bluuebunny/crossref_metadata_2025 huggingface dataset:
Fire in lichen-rich subarctic tundra changes carbon and nitrogen cycling between ecosystem compartments but has minor effects on stocks
Authors: Heim Ramona Julia , Yurtaev Andrey , Bucharova Anna , Heim Wieland , Kutskir Valeriya , Knorr Klaus-Holger , Lampei Christian , Pechkin Alexandr , Schilling Dora , Sulkarnaev Farid , Hölzel Norbert
Published: December 2021

Abstract. Fires are predicted to increase in Arctic regions due to ongoing climate change. Tundra fires can alter carbon and nutrient cycling and release a substantial amount of greenhouse gases with global consequences. Yet, the long-term effects of tundra fires on carbon (C) and nitrogen (N) stocks and cycling are still unclear. Here we used a space-for-time approach to investigate the long-term fire effects on C and N stocks and cycling in soil and aboveground living biomass. We collected data from three large fire scars (> 44, 28 and 12 years old) and corresponding control areas and used linear mixed-effects models in a Bayesian framework to analyse how the stocks and cycling were influenced by fire. We found that tundra fires did not affect total C and N stocks because a major part of the stocks was located belowground in soils, which were largely unaltered by fire. However, fire had a strong effect on stocks in the aboveground vegetation, mainly due to the reduction of the lichen layer. Fire reduced N concentrations in graminoids and herbs on the younger fire scars, which affected respective C / N ratios and indicated an increased post-fire competition between vascular plants. Aboveground plant biomass was depleted in 13C in all three fire scars. This could be related to a lower 13C abundance in CO2 in the ambient air because of increased post-fire decomposition, providing a source of 13C-depleted CO2. In soil, the relative abundance of 13C changed with time after fire because of the combined effects of microbial decomposition and plant-related fractionation processes. Our results indicate that in lichen-rich subarctic tundra ecosystems, the contribution of fires to the release of additional carbon to the atmosphere might be relatively small as soil stocks appear to be resilient.
Terrestrial records of glacial terminations V and IV and insights on deglacial mechanisms
Authors: Marra Fabrizio , Pereira Alison , Jicha Brian , Nomade Sebastien , Biddittu Italo , Florindo Fabio , Muttoni Giovanni , Niespolo Elizabeth , Renne Paul , Scao Vincent
Published: December 2021

Abstract. 40Ar/39Ar geochronology constraints to aggradational phases and grainsize variations show that the sedimentary filling of the Liri fluvial-lacustrine basin (central Italy) recorded the occurrence of deglaciation events associated with global meltwater pulses. Integrating these data with those from the Tiber River catchment basin, we find a precise match between the ages of gravel deposition and the occurrence of moderate sea-level rise events which anticipate those more marked during the glacial termination V and IV in the Red Sea relative sea level curve. Such correspondence suggests that gravel deposition is facilitated by melting of Apennine mountain range glaciers, which provide the water transport energy and a surplus of clastic input to the rivers draining the mountain regions and flowing into the Tyrrhenian Sea. Therefore, the thick gravel beds intercalated in the sedimentary filling of the catchment basins of the major rivers in central Italy may be regarded as an equivalent proxy of large deglaciation events, similar to the ice-rafted debris in northern Atlantic. Consistent with this hypothesis, we also show the close correspondence between the occurrence of particularly mild (warmer) minima of the mean summer insolation at 65° N and these early aggradational phases, as well as with other anomalous early sea-level rises occurred 750 ka and 540 ka at the onset of glacial termination VIII and VI, and 40 ka at the onset of the so-called Heinrich events.
River network and hydro-geomorphology parametrization for global river routing modelling at 1/12° resolution
Authors: Munier Simon , Decharme Bertrand
Published: December 2021

Abstract. Global scale river routing models (RRMs) are commonly used in a variety of studies, including studies on the impact of climate change on extreme flows (floods and droughts), water resources monitoring or large scale flood forecasting. Over the last two decades, the increasing number of observational datasets, mainly from satellite missions, and the increasing computing capacities, have allowed better performances of RRMs, namely by increasing their spatial resolution. The spatial resolution of a RRM corresponds to the spatial resolution of its river network, which provides flow direction of all grid cells. River networks may be derived at various spatial resolution by upscaling high resolution hydrography data. This paper presents a new global scale river network at 1/12° derived from the MERIT-Hydro dataset. The river network is generated automatically using an adaptation of the Hierarchical Dominant River Tracing (DRT) algorithm, and its quality is assessed over the 70 largest basins of the world. Although this new river network may be used for a variety of hydrology-related studies, it is here provided with a set of hydro-geomorphological parameters at the same spatial resolution. These parameters are derived during the generation of the river network and are based on the same high resolution dataset, so that the consistency between the river network and the parameters is ensured. The set of parameters includes a description of river stretches (length, slope, width, roughness, bankfull depth), floodplains (roughness, sub-grid topography) and aquifers (transmissivity, porosity, sub-grid topography). The new river network and parameters are assessed by comparing the performances of two global scale simulations with the CTRIP model, one with the current spatial resolution (1/2°) and the other with the new spatial resolution (1/12°). It is shown that CTRIP at 1/12° overall outperforms CTRIP at 1/2°, demonstrating the added value of the spatial resolution increase. The new river network and the consistent hydro-geomorphology parameters may be useful for the scientific community, especially for hydrology and hydro-geology modelling, water resources monitoring or climate studies.
MagIC v5.10: a two-dimensional message-passing interface (MPI) distribution for pseudo-spectral magnetohydrodynamics simulations in spherical geometry
Authors: Lago Rafael , Gastine Thomas , Dannert Tilman , Rampp Markus , Wicht Johannes
Published: December 2021

Abstract. We discuss two parallelization schemes for MagIC, an open-source, high-performance, pseudo-spectral code for the numerical solution of the magnetohydrodynamics equations in a rotating spherical shell. MagIC calculates the non-linear terms on a numerical grid in spherical coordinates, while the time step updates are performed on radial grid points with a spherical harmonic representation of the lateral directions. Several transforms are required to switch between the different representations. The established hybrid parallelization of MagIC uses message-passing interface (MPI) distribution in radius and relies on existing fast spherical transforms using OpenMP. Our new two-dimensional MPI decomposition implementation also distributes the latitudes or the azimuthal wavenumbers across the available MPI tasks and compute cores. We discuss several non-trivial algorithmic optimizations and the different data distribution layouts employed by our scheme. In particular, the two-dimensional distribution data layout yields a code that strongly scales well beyond the limit of the current one-dimensional distribution. We also show that the two-dimensional distribution implementation, although not yet fully optimized, can already be faster than the existing finely optimized hybrid parallelization when using many thousands of CPU cores. Our analysis indicates that the two-dimensional distribution variant can be further optimized to also surpass the performance of the one-dimensional distribution for a few thousand cores.
Generation and fate of basal meltwater during winter, western Greenland Ice Sheet
Authors: Harper Joel , Meierbachtol Toby , Humphrey Neil , Saito Jun , Stansberry Aidan
Published: December 2021

Abstract. Basal sliding in the ablation zone of the Greenland Ice Sheet is
closely associated with water from surface melt introduced to the bed in
summer, yet melting of basal ice also generates subglacial water year-round.
Assessments of basal melt rely on modeling with results strongly dependent
upon assumptions with poor observational constraints. Here we use surface and
borehole measurements to investigate the generation and fate of basal
meltwater in the ablation zone of Isunnguata Sermia basin, western
Greenland. The observational data are used to constrain estimates of the
heat and water balances, providing insights into subglacial hydrology during
the winter months when surface melt is minimal or nonexistent. Despite
relatively slow ice flow speeds during winter, the basal meltwater
generation from sliding friction remains manyfold greater than that due to
geothermal heat flux. A steady acceleration of ice flow over the winter
period at our borehole sites can cause the rate of basal water generation to
increase by up to 20 %. Borehole measurements show high but steady basal
water pressure rather than monotonically increasing pressure. Ice and
groundwater sinks for water do not likely have sufficient capacity to
accommodate the meltwater generated in winter. Analysis of basal cavity
dynamics suggests that cavity opening associated with flow acceleration
likely accommodates only a portion of the basal meltwater, implying that a
residual is routed to the terminus through a poorly connected drainage
system. A forcing from cavity expansion at high pressure may explain
observations of winter acceleration in western Greenland.
Experimental results of wake steering using fixed angles
Authors: Fleming Paul , Sinner Michael , Young Tom , Lannic Marine , King Jennifer , Simley Eric , Doekemeijer Bart
Published: December 2021

Abstract. In this article, the authors present a test of wake steering at a commercial wind farm. A single fixed yaw offset, rather than an optimized offset schedule, is alternately applied to an upstream wind turbine, and the effect on downstream turbines is analyzed. This experimental design allows for comparison with engineering wake models independent of the controller's ability to track a varying offset and correctly measure wind direction. Additionally, by applying the same offset in beneficial and detrimental conditions, we are able to collect important data for assessing second-order wake model predictions. Results of the article from collected data show good agreement with the FLOw Redirection and Induction in Steady State (FLORIS) engineering model and offer support for the asymmetry of wake steering predicted by newer models, such as the Gauss–curl hybrid model.
How Alberta Education’s First Nations, Metis, and Inuit Policy Framework influence students attitudes towards the Indigenous Peoples of Canada.
Authors: Prete Tiffany
Published: December 2021

For decades, Indigenous education in Canada has implemented policies that provide a more culturally relevant curriculum for Indigenous students. It is thought that such a curriculum will improve morale and academic success in Indigenous students. Despite these efforts, a gap still exists between Indigenous students and their counterparts. Little attention has been given to the role that race and racism plays in the lives of Indigenous students. This study examines whether a need exists for race and racism to be addressed in the public school system. Using an Indigenous research methodology, a survey was administered to elicit non-Indigenous attitudes towards the Indigenous peoples of Canada. It was found that in the absence of an antiracist education, nonIndigenous students held negative perceptions of Indigenous peoples, as well as lacked an understanding of racism and its significance.
UPAYA PENINGKATAN KOMPETENSI GURU DALAM MENYUSUN SILABUS DAN RPP MELALUI SUPERVISI AKADEMIK YANG BERKELANJUTAN DI SMP NEGERI 3 MUARA BUNGO
Authors: Arief Marief
Published: December 2021

Seorang guru diharuskan melakukan perencanaan, pelaksanaan dan evaluasi pembelajaran. Demikian pula yang terjadi dengan proses belajar mengajar di sekolah yang harus memiliki perencanaan. Penelitian ini meliputi lima unsur yaitu; membuat program tahunan, membuat silabus, membuat program semester, membuat RPP, serta membuat program ulangan atau evaluasi. Penelitian ini bertujuan untuk melakukan upaya peningkatan kompetensi guru di SMP Negeri 3 Bungo serta melihat sejauh mana langkah supervisi akademik kepala sekolah dapat meningkatkan kompetensi guru dalam penyusunan silabus dan Rencana Pelaksanaan Pembelajaran. Berdasarkan hasil analisa pada tahun pelajaran 2018/2019 di SMP Negeri 3 Bungo muncul permasalahan rendahnya guru yang membuat perencanaan pembelajaran khususnya penyusunan silabus dan RPP.
Palavra saúde: podcasts, linguística cognitiva, saúde e ecologia humana
Authors: Machado Alex Sander Dias , Arruda Natalia Lemos , Cunha Gustavo Augusto Santos da
Published: December 2021

Inovações no âmbito de promoção à saúde devem buscar ações de educação e comunicação em saúde.  A neurolinguística é a parte da ciência que estuda a elaboração cerebral da linguagem. A memória musical funciona a partir da ativação de áreas como o hipocampo, que se relaciona com resgates de conhecimentos aprendidos. O projeto Palavra Saúde baseia-se nesse processo associativo e reúne textos orientados pela linguística cognitiva a partir de verbetes do dia a dia e música, conectando educação em saúde com memórias do indivíduo. A utilização de mini-programas em Podcasts foi a ferramenta mais viável no contexto pandêmico e a divulgação em rádios e plataformas musicais digitais garantiram o alcance do projeto. Durante 2020, 10 mini-programas foram criados e divulgados. O objetivo foi alcançado, conectando o novo conhecimento e uma memória afetiva, podendo-se concluir um ganho no âmbito da promoção da saúde entre os ouvintes e habitantes do Vale do Jequitinhonha.
TRABALHO ARTÍSTICO INFANTOJUVENIL
Authors: Magalhães Stephanie Carvalho
Published: December 2021

O presente estudo possui o escopo de analisar o trabalho artístico infantojuvenil, buscando compreender suas origens e as legislações que solidificam sua constitucionalidade no Ordenamento Jurídico Brasileiro e nos diplomas internacionais. Dessa forma, o objetivo dessa pesquisa será examinar a finalidade das atividades exercidas pelos infantes e compreender o enquadramento dessa relação jurídica na seara trabalhista, em virtude das inúmeras controvérsias doutrinárias - em que se reverberem as distinções entre trabalho e atividade artística -, e também a previsão constitucional acerca do tema. A metodologia utilizada na confecção da pesquisa foi a hipotético-dedutiva através da qual, realizou-se o levantamento de hipóteses, posteriormente testadas, e que, por meio de suas construções lógicas, puderam deslindar a questão proposta.
Моделирование взаимодействия углеродных нанотрубок с атомами водорода
Authors: Улжаев У.Б. , Алябьев Д.В. , Ядгаров И.Д. , Халилов У.Б.
Published: December 2021

Методами молекулярной. динамики (ReaxFF, LAMMPS) проведены модельные эксперименты по рассеянию атомов водорода поверхностью углеродной нанотрубки (температура нанотрубки – 300 К, 600 К). В частности, наблюдаются процессы адсорбции, инкапсуляции рассеиваемых атомов. Показано, что характер протекающих процессов зависит как от энергии рассеиваемых атомов, так и от температуры нанотрубки. Кроме того, процессы адсорбции и инкапсуляции зависят от количества водорода, поступающего в нанотрубку, и угла падения. Показано, что при энергии атомов водорода 50 эВ, атомы в основном адсорбируются поверхностью нанотрубки, а при энергии 90 эВ лишь часть атомов водорода адсорбируется поверхностью нанотрубки, другая часть атомoв адсорбируется внутри нанотрубки.
Investigating University Students’ Perceptions About Two Different Cases of Foreign Language Courses
Authors: İLHAN Elif , ZERENAY Ceyda
Published: December 2021

This study investigates university students’ perceptions of two different cases of foreign language courses conducted in L1&L2 and in only L2. This qualitative study was conducted as a multiple case study. The data were obtained via a semi structured and analysed through content analysis. The study mainly revealed the students had overwhelmingly positive feelings about the courses in only L2 as in the second case. They explained some (dis)advantages about both cases of the courses in terms of efficiency, contribution to their vocabulary/grammar knowledge and listening /speaking skills. The frequency levels of both advantages and disadvantages regarding both cases stated by the students were so close. Based on the findings, it can be suggested that a student-teacher driven policy should be implemented to assist the process in using L1 appropriately and necessarily based on the students’ perceptions and preferences.
Positive Characteristics in Primary School Teachers: The Interactive Roles of Psychological Capital and Mindfulness in Teaching
Authors: ASLAN GÖRDESLİ Meltem , AYDIN SÜNBÜL Zeynep
Published: December 2021

The reinforcing effects of positive characteristics in maintaining teachers’ and students’ psychological health have been well documented. However, there has been very little research into the determinants of what constitutes positive characteristics among teachers. Neither the full role played by mindfulness nor the psychological capital of teachers with positive characteristics remains unknown. This study marks the beginning of an investigation into such an issue. The sample of the study involved the participation of 374 teachers. In Model 1, the mediating role of psychological capital was tested in the relationship between mindfulness in teaching and teacher positivity. Meanwhile, in Model 2, the mediating role of mindfulness in teaching was tested in the relationship between psychological capital and positive teacher characteristics. In Model 1, the standardised path coefficients between the variables were not found to be statistically significant, thus prompting the test of a second structural model. The results showed that mindfulness in teaching appeared to constitute a full mediator in the relationship between psychological capital and positive characteristics among primary school teachers.
Links Between Disadvantage and Educational Achievement in a Low-income Urban Setting in Bangalore, India
Authors: CHATTERJEE Arshia , BURNS Stephanie
Published: December 2021

This study focused on the experiences that contributed to the academic achievement of students in disadvantaged settings in India. In India, young people in disadvantaged neighbourhoods are at higher risk of underachievement and dropping out of school. However, some of them achieve highly despite their adverse circumstances and experience. Through interviews with 12 high achievers and their school principal, this study explored the perceived factors that contributed to their academic achievement. Data were analyzed using interpretative phenomenological analysis, and findings indicate a combination of protective factors at different levels – individual, family, school, and community – that contribute to resilience and achievement. The supportive relationships that these adolescents have at the different levels contribute to their achievement directly and indirectly. The findings are discussed in relation to theory with future considerations for Indian-centred research that can inform interventions in disadvantaged and low-income urban communities.
Bisphosphonate-induced osteonecrosis of the jaws: a literature review
Authors: Teófilo Nayane de Andrade , Denardin Caio , Da Silva Thiago Quirino Mota , Margute Túlio Garcia , Rossato Andrei Rabenschlag , Maione Max Soares , Margute Tiago Garcia , Dos Santos Igor Fonseca
Published: December 2021

Bisphosphonates are widely used, whether in osteoporosis or malignant bone disorders. Therefore, it is necessary that there is sufficient knowledge about the adverse effects of this drug, especially in relation to Osteonecrosis of the Jaws Developed by Bisphosphonates, which is a pathology generated in the gnathic bones. So, the following question was asked in the research problem: What is the current situation regarding the use of bisphosphonates and the onset of osteonecrosis of the jaw? Searches were carried out on digital library websites in search of articles and research in books by renowned authors. Inclusion and exclusion criteria for articles found were defined. The verification of each article was carried out so that it could have perspective and follow-up on the subject discussed. The following databases were used: PUBMED, BIREME and LILACS, and SCIELO between the years 2007 to 2019. It was concluded then that Bisphosphonates play a very important role as a cause of osteonecrosis of the jaws, where the prognosis will be worse if the patient is treated with intravenous rather than oral types.
Effectiveness of Neem Oil Upon Pediculosis
Authors: Issac Lincy
Published: December 2021

Background: It is widely accepted that the school environment favors in the spread of the infestation simply be- cause it affords opportunity for continual close contact of children. So the investigator motivated to try out neem oil application and to see its effect in children with pediculosis. Neem oil is available locally, is of low cost and effective for treating head lice. Objective: To test whether the neem oil is effective in the treatment of pediculosis among school children. Methods: An experimental research approach with true experimental design was used. The present study was conducted in the Don Bosco Beatitudes Orphanage, Vyasarpady, for control group and Dazzling Stone Orphanage for experimental group, Kundrathur. The sample size was 60 and was selected through simple random sampling method, 30 were assigned to control group and 30 were assigned to experimental group. The investigator used a demographic variable proforma, degree of pediculosis, observational checklist on signs and symptoms of pediculosis, and interview schedule on knowledge regarding prevention of pediculosis and a rating scale on the level of satisfaction on application of neem oil. Results In control group, there was no significant difference in the degree of pediculosis before neem oil application (M=2.70, SD=0.450) and after neem oil application (M=2.73, SD=0.450). In contrast, in the experimental group, degree of pediculosis was decreased (M=0.70, SD=0.466) when compared to the degree of pediculosis before neem oil application (M=2.73, SD=0.450). The difference was found to be statistically significant at p< 0.001 degree of pediculosis and it can be attributed to the effectiveness of neem oil application. Most of the children (73.3%) were highly satisfied and only a significant percentage of children (26.7%) were satisfied with the neem oil application in the experimental group. Conclusion: It is possible to reduce pediculosis by the application of neem oil among school children.
A Descriptive Study to Assess the Mental Health Literacy among the Nursing Students (18-20 Years of) in the Selected College at Puducherry
Authors: S. Suvitha , E. Rama , T. Raviranjan , K. Ranjini
Published: December 2021

A descriptive study to assess the Mental Health Literacy among the Nursing students (18-20 years of) in the selected college at Puducherry. The objectives of the study was to assess the mental health literacy among the Nursing students. The research approach selected for the study was quantitative research approach and descriptive research design. The study was conducted at MTPG&RIHS at Puducherry. Total 100 B.Sc. Nursing Students who completed the subject mental health nursing were selected based on Non-probability convenient sampling. The researcher used standardized tool, Mental Health Literacy Scale (MHLS) data collection. The findings of the study revealed that 82% of samples had moderate level of knowledge on Mental Health Literacy, 18% of samples had adequate knowledge about Mental Health Literacy and none of the samples had inadequate knowledge regarding Mental Health Literacy. Regarding knowledge, out of 100 samples, 82% of subjects are belongs to moderate knowledge about Mental Health Literacy and Mental illness. Remaining 18% had adequate knowledge about Mental Health Literacy and Mental Illness none of the samples had inadequate knowledge about the Mental Health Literacy and Mental Illness.
Phát triển kỹ năng giải quyết vấn đề cho sinh viên năm thứ nhất Trường Đại học Tiền Giang thông qua học phần Pháp luật đại cương
Authors: Nguyễn Thị Khuyến
Published: December 2021

Pháp luật đại cương là học phần bắt buộc đối với sinh viên năm thứ nhất ở các trường đại học. Học phần trang bị cho sinh viên các kiến thức về nhà nước, pháp luật và một số quy định cơ bản của một số ngành luật trong hệ thống pháp luật Việt Nam. Để đạt kết quả tốt trong học phần, sinh viên phải có kỹ năng giải quyết vấn đề. Vậy, kỹ năng giải quyết vấn đề là gì; các nguyên nhân nào ảnh hưởng đến kỹ năng giải quyết vấn đề của sinh viên; thực trạng kỹ năng giải quyết vấn đề của sinh viên năm thứ nhất Trường Đại học Tiền Giang như thế nào; để phát triển kỹ năng giải quyết vấn đề của sinh viên năm thứ nhất thông qua học phần Pháp luật đại cương thì cần có các biện pháp nào; đó là những nội dung chính tác giả muốn chia sẻ trong bài viết này.
Ứng dụng công nghệ blockchain trong cách mạng hóa ngành công nghiệp quản lý nhân sự
Authors: Nguyễn Quốc Khánh , Tô Thị Thanh Hà
Published: December 2021

Cuộc cách mạng công nghiệp lần thứ tư (4IR) đã và đang tạo ra những thay đổi đột phá đối với mô hình kinh doanh, dự đoán các động lực chính của sự chuyển đổi sẽ có tác động sâu sắc đến bối cảnh công việc trong tương lai, từ tạo việc làm đến chuyển đổi vị trí, từ tăng năng suất lao động đến mở rộng khoảng cách kỹ năng,... Dịch Covid -19 càng chứng minh điều đó rõ nét hơn bao giờ hết. Nhằm tìm hiểu phản ứng của các doanh nghiệp, làm thế nào để chuyển đổi nhân sự và làm thế nào để ngăn chặn sự thiếu hụt tài năng trong việc làm. Trên cơ sở phân tích thực trạng và xu thế, bài viết đặt ra một số thách thức và gợi ý một số cơ hội nhằm giúp doanh nghiệp đánh giá lợi ích và gánh nặng của 4IR, có một cái nhìn về động lực của thay đổi đang diễn ra và tìm được những biện pháp để ổn định các kỹ năng,…
Özel Sağlık Bakım Gereksinimi Olan Çocukların Ebeveynlerine Yönelik Eğitim Programlarının Önemi
Authors: ÇIRLAK Ahu , KILIÇARSLAN TÖRÜNER Ebru
Published: December 2021

Günümüzde teknolojinin gelişimi ile doğum komplikasyonu gelişen ve hayatta kalan bebekler genetik geçişli hastalıklar, beslenme, çevre değişikliklerinin neden olduğu kronik hastalıklar gibi gelişen durumlar sonrası özel sağlık bakım gereksinimi doğan çocuklar artış göstermektedir. Bu alanda sayının artması çocukların bakım gereksinimini dolayısı ile ebeveynlerin bakım yükünü de arttırmaktadır. Bu süreçlerde ebeveyn stresini azaltmak, çocuğun uygun ve doğru bakımı almasını sağlamak, çocuk ve ebeveynin yaşam kalitesini arttırmak, ebeveyn çocuk ilişkisini güçlendirmek ve sağlık bakım giderlerini azaltmak amacıyla ebeveynlere yönelik sistemli eğitim programları uygulanmalıdır.
Semptomatik Rotator Kaf Tendinopatili Bireylerde Dinamik Bantın Akromiohumeral Mesafe, Omuz Propriosepsiyonu ve Eklem Hareket Açıklığı Üzerindeki Akut Etkisinin Araştırılması
Authors: KOÇ Meltem , AYDOĞMUŞ Hüseyin , DİNÇ ELİBOL Funda , OSKAY Deran , BAYAR Kılıçhan
Published: December 2021

Giriş: Dinamik bant 2009 yılında kas-iskelet sistemi fizyoterapisti Ryan Kendrick tarafından geliştirilen, dört yönde ve %200'den fazla esneme özeliği olan elastik terapötik bir banttır. Tedavide nörofizyolojik etkisinin yanı sıra güçlü biomekanik etkisi bulunmaktadır. Amaç: Bu araştırmanın amacı, semptomatik rotator kaf tendinopatili (RKT) bireylerde semptomatik omuza uygulanan dinamik bantın akromiohumeral mesafe, omuz eklem hareket açıklığı ve propriosepsiyon üzerindeki akut etkisini araştırmaktı. Yöntem: Çalışmaya RKT’li, yaşları 34-65 arasında değişen ve yaş ortalamaları 54.35±8.04 olan 17 birey dahil edildi. Akromiohumeral mesafe (AHM) Ultrason cihazı ile omuz nötral ve 60° abduksiyon pozisyonunda değerlendirildi. Omuz eklemi propriosepsiyon duyusu dijital inklinometre ile aktif repozisyon testi kullanılarak 30° ve 60° omuz fleksiyon açılarında değerlendirildi. Omuz ağrısız ve tam eklem hareket açıklığı (fleksiyon, abduksiyon, internal ve external rotasyon) standart gonyometre ile değerlendirildi. Bütün değerlendirmeler bantlama öncesi ve sonrası (30 dakika) olmak üzere 2 kez tekrar edildi. Karşılaştırmalarda normal dağılım gösteren veriler için eşleştirilmiş t testi, normal dağılım göstermeyen veriler için Wilcoxon testi kullanıldı. Bulgular: Bantlama öncesi ve sonrası AHM nötral (0°) ve 60º abduksiyon ölçümlerinde istatistiksel olarak anlamlı fark vardı (p
Ipertiroidismo e tiroidite autoimmune in età evolutiva
Authors: Pellegrin Maria Chiara , Occhipinti Alessandro , Bossini Benedetta , Norbedo Stefania , faleschini Elena , Barbi Egidio , Bizzarri Carla , Tornese Gianluca
Published: December 2021

Hyperthyroidism is a rare clinical entity in paediatric age. In most cases the etiology is autoimmune and goiter represents the typical presentation. Ophthalmopathy is rare and can precede the diagnosis of autoimmune hyperthyroidism. Thyrotoxicosis caused by the hyperthyroid phase of Hashimoto’s thyroiditis must be carefully distinguished from Graves’ disease (GD), since the first condition has a better prognosis for spontaneous remission. Three treatment options are currently available for the management of paediatric GD. First-line therapy is antithyroid drugs, while thyroidectomy and radioiodine are considered on relapse. A lower remission rate and a higher risk of adverse events are observed after the first course of methimazole in childhood with respect to adulthood. Children and adolescents may require a prolonged antithyroid treatment, but an overall consensus regarding the optimal regimen is lacking.
The cost-effectiveness of investments made in the treatment of nervous system disorders in HIV patients in Brazil
Authors: Martins Marcos Vinicius Teixeira , Brito Veronica Perius de , Oliveira Stefan Vilges de
Published: December 2021

Introduction: Neurological manifestations in patients with the human immunodeficiency virus (HIV) occur from contamination to advanced levels of immunosuppression. In approximately 15% of cases, neurological complications are observed as initial manifestations and in about 85%, central nervous system involvement is detected. Objectives: Analyze the cost-effectiveness of investments made in the treatment of nervous system disorders in HIV patients in Brazil. Methodology: Epidemiological study with data from the Sistema de Informações Hospitalares do Ministério da Saúde, between 2011 and 2020 in Brazil. Results: There were 16665 hospitalizations, with an average stay of 17.74 (±2.71) days, an average cost of R$ 1473.70 (±142.88) and a mortality rate of 14.23% (±2.23). The average costs, length of stay and mortality rate from 2011 to 2014 were R$ 1291.11 (±97.51), 18.83 (±0.52) days and 15.20% (±1.83). Between 2017 and 2020, R$ 1599.61 (±56.79), 16.85 (±0.62) days and 12.09% (±1.39). By region, there are 29.77% (±0.69), 11.60% (±0.49), 29.37% (±0.69), 19.57% (±0.60), 9.70% (±0.44) of the treatments in the North, Northeast, Southeast, South and Midwest, respectively. The average investment was higher in the Northeast, R$ 1754.26 (±76.54), and lower in the Midwest, R$ 1335.16 (±49.23). For these sites, mortality rates were 17.38% (±1.21) and 13.92% (±0.87), with mean stays of 21.90 (±2.30) and 13.81 (±1.86) days, respectively. Conclusions: There was an increase in investments, a reduction in the mortality rate and average stay over the period. In addition, significant disparities were noted when comparing national regions, a fact that may be associated with deficiencies in infrastructure.
Integrative review, XIII Paulista Congress of Neurology, May 2021; São Paulo (SP). Efficacy of cannabidiol in improving the quality of life of Parkinson´s Patient; ITPAC-Palmas (TO); 2021
Authors: Souza Ellen Lelis de , Silva Marianna Tonaco , Fonseca Marianne Morais de Pinho da , Miranda Wanderson Stewart Parreira
Published: December 2021

Introduction: Parkinson’s disease (PD) is a neurodegenerative disease, caused by an imbalance between the inhibitory action of dopamine and the excitatory action of acetylcholine due to dopamine restriction, characterized by motor and non-motor symptoms. The phytocannabinoid cannabidiol (CBD) may be effective for the treatment of symptoms in PD, offering better quality of life. Objectives: To verify the evidence for the efficacy of cannabidiol in the treatment of patients with PD about the improvement of quality of life. To analyze its applicability in controlling involuntary movements in PD patients. Methods: A search in the databases LILACS, BIREME, SCIELO, SCIENCE, EBSCO, PUBMED, using the bibliographic research method, and by means of integrative review. The descriptor cannabidiol was associated with the words: therapeutic use, parkinsonism, and quality of life. The selection included articles published between 2000 and 2020, in Portuguese, English and German languages. Results: Therapeutic effects of cannabidiol were promising in PD, such as neuroprotective action, reduction of motor symptoms, cognitive and quality of life improvement with few relevant adverse effects. Among the 16 articles, 8 demonstrate an improvement in symptoms and the others cite improvement in psychiatric and cognitive symptoms, thus reflecting that cannabidiol is a promising for quality of life improvement. Conclusion: Although cannabidiol has shown efficacy in the therapy of Parkinson’s patients in clinical and preclinical studies, there is still a need for further studies and investigations on the therapeutic effects of this compound. Thus, cannabidiol may become a first choice treatment for PD, promote patients and families a better living with the disease, and positive reflexes.
Lambert-Eaton Myasthenic Syndrome in Brazil: a single center experience
Authors: Pinto Icaro França Navarro , Pinto Wladimir Bocca Vieira de Rezende , Farias Igor Braga , Badia Bruno de Mattos Lombardi , Costa Gustavo Carvalho , Marin Carolina Maria , Jorge Ana Carolina Souza , Souto Emília Correa , Serrano Paulo de Lima , Machado Roberta Ismael Lacerda , Bezerra Márcio Luiz Escorcio , Oliveira Acary Souza Bulle , Souza Paulo Victor Sgobbi
Published: December 2021

Introduction: Lambert-Eaton Myasthenic Syndrome (LEMS) is an ultrarare autoimmune disorder of neuromuscular junction characterized by proximal muscle weakness, arreflexia and autonomic dysfunction due to presynaptic dysfunction caused by autoantibodies against the P/Q-type voltagegated calcium channel with diminished release of acetylcholine. LEMS can occurs as a primary autoimmune disorder or as paraneoplastic disorder with more than half of LEMS cases associated with small cell lung cancer. Objectives: The main objective of this study is described clinical, epidemiological, serological, and neurophysiological findings of a Brazilian cohort with definitive diagnosis of Lambert-Eaton Myasthenic Syndrome (LEMS). Results We identified eight patients with definitive LEMS with a 2:1 male/ female prevalence, all present with proximal muscle weakness with lower limb predominance and the most common autonomic dysfunction were xeropthalmia in 100% of patients, orthostatic hypotension presented in 6 of 9 patients and erectile dysfunction in all male patients. Conclusions: LEMS should always be suspected in patients with proximal muscle weakness associated with autonomic dysfunction and in this Brazilian cohort most cases were seronegative and do not have correlation with small-cell lung cancer in contrast with the current knowledge of disease.
Oculogyric Crisis in a patient with PURA Syndrome
Authors: Pinto Icaro França Navarro , Pinto Wladimir Bocca Vieira de Rezende , Farias Igor Braga , Badia Bruno de Mattos Lombardi , Costa Gustavo Carvalho , Marin Carolina Maria , Jorge Ana Carolina Souza , Souto Emília Correa , Serrano Paulo de Lima , Machado Roberta Ismael Lacerda , Oliveira Acary Souza Bulle , Souza Paulo Victor Sgobbi
Published: December 2021

Context: PURA syndrome is a neurodevelopmental disorder characterized by neonatal hypotonia, delayed psychomotor development, early-onset feeding difficulties and an epileptic encephalopathy. Case Report: A 3-month-old Brazilian boy presented with severe neonatal hypotonia associated with feeding difficulties due to serious dysphagia requiring nasoenteral tube feeding. Excessive drowsiness, poor social interaction and repetitive episodes of involuntary abnormal upward eye movements and ocular version with short duration were also reported by parents. Neurological examination revealed severe axial and upper limb hypotonia, orofacial dyskinetic movements and episodes of abnormal eye movements with upward ocular deviation with less than 30 seconds in duration compatible with oculogyric crisis. It was performed Whole-Exome sequencing and it was identified a new pathogenic variant in PURA gene that establisehd the final diagnosis of PURA Syndrome or Autosomal Dominant Mental Retardation type 31, MDR 31 (OMIM #616158). Conclusions: PURA Syndrome emerges as one of the major differential diagnoses of neonatal hypotonia and in addition, we can consider the early manifestation of oculogyric crisis as a phenotypic expansion of the syndrome, making its diagnosis even more challenging, since epileptic encephalopathies and neurotransmitter deficiency-related diseases present with a similar clinical course.
Overview of hospital admissions for migraine and other cephalic pain syndromes in Brazil and regions, 2015 to 2019
Authors: França Nathália Moreira de Almeida , Bonfim Bárbara Araújo , Almeida Mateus Ribeiro de , Avena Kátia de Miranda
Published: December 2021

INTRODUCTION: Headache is defined as a pain in the cephalic segment, and is the fourth cause of demand for emergency care. In Brazil, 98% of women and 95% of men will suffer some episode during their lives. It causes physical, social, labor, and economic damage, and is the third leading cause of years lived with disability. Thus, it is relevant to investigate hospital admissions for migraine and other cephalic pain syndromes. OBJECTIVES: To analyze hospital morbidity due to migraine and other cephalic pain syndromes in Brazil between 2015 and 2019. METHODS: Epidemiological, retrospective, descriptive study, carried out through the Hospital Information System (DATASUS). Variables: sex, ethnicity, age, hospital stay, costs and deaths. RESULTS: Registered 49,508 hospitalizations for migraine and other cephalic pain syndromes from 2015-2019; predominantly women (65.7%), between 20-39 years (37.3%), 40-59 years (29.4%), which occurred mainly in the Southeast (33.1%) and South (23.6%) regions. The average cost per hospitalization was R$ 421.50. The mean hospital stay was 3.9 days, ranging from 3.1 days in the South to 4.8 days in the Northeast, with no differences between genders. There were 384 deaths, of which 56.3% were women. CONCLUSION: The morbidity profile due to cephalic pain syndromes is composed of women, aged 20-39 years, living in the Southeast region. It is important to intensify investments in prevention, diagnosis and treatment, seeking to reduce hospitalizations, the impact on the health system and to improve the patient’s quality of life.
Opsoclonus-myoclonus syndrome in pedriatic patient from Campo Grande (MS): case report
Authors: Espindola Mylena Delamare , Souza Thaynara Maria Maran de , Boaventura Gabriel Loureiro Seleghim , Maldonado Maria José Martins
Published: December 2021

Context: Opsoclonys-myoclonus syndrome (OMS) is a rare neurologic disorder characterized by acute or chronic subcortical myoclonus and cerebellar ataxia at 6 months to 3 years-old children with rates of incidence expressed as 0.18 per 1.000.000 person- year. With nonspecific physiopathology, the only definitive finding is an elevated lymphocyte and positive B-cells count on the cerebrospinal fluid (≥11 cels/mm³) along with 50 to 93% cases reported from the National Pedriatric Myoclun Center (1989-2013) presenting oligoclonal bands. The diagnosis is established by clinical evaluation with exclusion criteria based on the presence of structural central nervous system damage and the aggressive treatment includes immunomodulatory therapy for behavior and cognitive stabilization. Case report: This paper aims to describe a case of a 1-year-old premature pediatrician patient presenting OMS in the absence of fetus distress due to pre- eclampsia condition with long-term hospitalization. After hypotonia, psychomotor agitation and vomit episodes, the patient was referred to Campo Grande (MS) where worsened to globus myoclonus, opsoclonus and nystagmus after 25 days of hospitalization, symptomatology responsive to Propranolol 10mg a day with regression of the clinical and neurological condition. Conclusion:Although OMS is a rare condition with variable prognosis, children appear to respond to pharmacological and non-pharmacological treatment improving the quality of life.
Possible association of stroke with higher whole blood viscosity: study in a high altitude (Cusco 3399 masl)
Authors: Saldaña Charles Huamani , Solis Franklin Miranda- , Montalvo Víctor Oré , Bayona William , Perez Carlos , Acuña Juan Carlos , Córdova Golda , Pacheco Luis , Antonio Dario
Published: December 2021

Background. Risk factors for stroke have been extensively studied, however, few studies have been carried out in high-altitude cities. Objectives. To evaluate the difference in blood viscosity, using direct methods, in stroke patients versus patients without stroke to discover any possible association. Design and setting. A cross-sectional study was carried out in the city of Cusco, Peru (3399 m.a.s.l). Methods: Participants included stroke patients with less than three days of illness and controls without stroke. Viscosity levels were measured in all patients using a cone-plate viscometer. Blood viscosity was evaluated at 10, 20, 30 and 40 revolutions per minute (RPM) because blood is considered a nonNewtonian fluid. Plasma viscosity was evaluated at 100RPM. All viscosity units are expressed as means standard deviations (SD) in centipoises (cP). Results: A total of 204 patients were included (61 cases/143 controls). The mean age was 67.5 (SD:15.9), and 88 (43%) were women. The means of blood viscosity for 10, 20, 30RPM in the stroke cases were 5.85cP (SD:1.21), 5.22cP (SD:1.09), and 4.91cP (SD:1.02), and 4.81cP (SD:1.02) respectively. For the controls were of 5.57cP (SD:1.19), 4.89cP (SD:4.85), 4.63cP (SD:0.97), 4.56cP (SD:0.95), respectively. All measured means were tested with significant differences (p <0.01). Plasma viscosities were 1.43cP (SD:0.17) for the stroke cases and 1.49cP (SD:0.23) for controls (p=0.05). Conclusions: This study found that blood viscosity is 0.3cP higher in stroke patients. This suggests that blood viscosity could play a role in the etiology. The results presented are preliminary and the study is still under development.
Brain Ischemia associated with COVID-19 and PFO - Case Report
Authors: Brandão André Iglesias , Vasconcelos Luiz Paulo Bastos , Silva Carolina de Almeida e , Valente Raul de Barros , Silva Danilo Jorge da , Costa Pedro Ivo Machado Campos de Araujo , Silva Matheus Henrique Freitas , Pinto Ygor Torres , Mascarenhas André Lustosa , Paixão Lorena Cândida Ferreira , Carli Gabriela de Paula , Pires Leopoldo Antônio
Published: December 2021

Context: COVID19 has better known respiratory impacts than cardiovascular1 and high D-dimer as the most significant coagulation parameter2 . Otherwise, paradoxical embolism due to Patent Foramen Ovale (PFO) and Ischaemic Cerebral Vascular Accident (iCVA) mechanisms associated are poorly documented3, 4 . We aimed to report an associated case of iCVA and PFO and highlight COVID19 hypercoagulability triggering thromboembolisms. Case report: CTT, 76y, female, hypertensive, former-smoker was hospitalized with right-hemiplegia, transcortical aphasia, dysarthria by iCVA and evolved with headache, odynophagia, fever, chills. RT-PCR-SARS-Cov2: positive; chestCT: 25% bilateral pulmonary involvement, ground-glass opacities. 8days later, was transferred to ICU-COVID-HU-UFJF; D-dimer=827. In 30days, went to ward with O2-dependent pulmonary sequelae; CT-angiography excluded Pulmonary Thromboembolism. Searched iCVA mechanism, ECO detected PFO=2.8mm and Interatrial Septum aneurysm. Prescribed anticoagulants. Subsequently, presented right-clonus, further previous RankinScale=5. Requested brain-MRI pointed lobar hemorrhage with mass effect in recent iCVA’s territory (left-Middle Cerebral Artery). After 10days, a head-CT evidenced partial resorption and reduced mass effect. Patient was discharged taking rivaroxabana. Conclusions: Retrospectively, we suspected that COVID19 hypercoagulability triggered Deep Vein Thrombosis and the consequent PFO paradoxical embolism, which caused iCVA. Therefore, vascular pathologies in COVID19 deserve further studies. Treatment for secondary prevention in iCVA by PFO is uncertain3 .
SleepUp, a Digital Therapeutics Platform for Insomnia
Authors: Pires Gabriel Natan , Sousa Ksdy Maiara Moura , Maganete Thábita , Redondo Paula Villena , Bonaldi Renata Redondo
Published: December 2021

Background: Cognitive-Behavioral Therapy for Insomnia (CBTi) is the gold-standard treatment for chronic insomnia. Although effective, CBTi is not easily accessible due to a shortage of specialized professionals and high treatment costs. Online CBTi (CBTi-O) has been proposed as a more accessible and affordable treatment option. CBTi and CBTi-O are equally effective, and some apps have already been approved by regulatory agencies in USA (Somryst™) and UK (Sleepio™). Objetives: SleepUp is a digital therapeutics solution for insomnia, intended to provide evidence-based treatment in an easily accessible format. Methods: The treatment program is based on CBTi-O, composed by seven therapeutic modules (sleep hygiene, relaxation and meditation, psychoeducation, stimulus control, cognitive restructuring, sleep restriction and paradoxical intention). Users are monitored with a sleep log and validated questionnaires assessing insomnia symptoms, sleepiness, sleep quality and sleep hygiene. Additional therapy modules are included, encompassing mindfulness and other meditation techniques. For refractory cases or for those with comorbidities, remote appointments with medical doctors and psychologists specialized in sleep medicine are available. Results: SleepUp is an early-stage startup and its solutions for sleep and insomnia are being constantly developed and improved. The app is already available in Brazil and USA, both for Android™ and IOS™ devices. Preliminary results demonstrate that the treatment is effective, reducing insomnia symptoms in 28%, (n=1700), improving sleep hygiene scores in 32% (n=100) and increasing sleep efficiency in 16% (n=2500). Conclusion: SleepUp aims at providing a more accessible alternative to the treatment of insomnia, based on CBTI-O, an effective and safe therapeutic approach.