bluuebunny/crossref_metadata_2025 huggingface dataset:
Hubungan Sistem Informasi Manajemen Kepegawaian (SIMPEG) Dengan Kualitas Pelayanan Administrasi Kepegawaian
Authors: Karina Karina , Ibrahim Tatang , Dian Dian
Published: July 2023

Personnel management information system (SIMPEG) is a system used to store employee data, one of the institutions that has implemented a personnel management information system (SIMPEG) as a system for storing employee data and facilitating services is the Office of the Ministry of Religion of West Bandung Regency. This study aims to find out: 1) how is the personnel management information system (SIMPEG) at the office of the Ministry of Religion of West Bandung Regency, 2) how is the quality of personnel administration services at the office of the Ministry of Religion of West Bandung Regency, 3) how is the relationship between the personnel management information system (SIMPEG) with the quality of personnel administration services at the office of the Ministry of Religion of West Bandung Regency. This research is descriptive, using a quantitative approach, the type of correlation. The data collection technique used is a questionnaire questionnaire. Then the data analysis techniques in this research are instrument test (validity and reliability), partial indicator analysis test, prerequisite test (normality and linearity test), and correlation test. Based on the results of the questionnaire distribution, the variable category x (SIMPEG) includes high qualifications with an average score of 4,54. Based on the results of the questionnaire distribution, the variable y (quality of personnel administration services) includes high qualifications with an average value of 4,41. The relationship between the personnel management information system (SIMPEG) and the quality of personnel administration services based on correlation testing, the results obtained from the correlation coefficient of 0,674 This shows that the relationship between the personnel management information system variable and the quality of personnel administration services, the strength level is at 0,674, so it can be interpreted these results are in the category 0.60 – 0.79, it can be interpreted that between these variables have a strong relationship.
Pengaruh Tata Ruang Kantor terhadap Kinerja Guru di Madrasah Pembangunan
Authors: Yuniarti Dwika , Waruwu Nurdelima , SAM Mu'arif
Published: July 2023

This study aims to determine the effect of office layout on teacher performance at Madrasah Pembangunan UIN Jakarta. This type of research is quantitative with a linear regression analysis approach. This study uses probability sampling where the population is MP UIN Jakarta teachers. Of the total 165 sample teachers used in this study were 63 teachers from all levels with specifications, 34 MI teachers, 19 MTs teachers, and 10 MA teachers. The research instrument was a questionnaire, document study, and interviews. The questionnaire was used as the main data collection which was distributed to the research subjects, while document study and interviews were used as complementary techniques to obtain data. The research result states that there is a significant influence between the influence of office layout on teacher performance at MP UIN Jakarta. This can be seen from the data processing results of the calculation of SPSS ver 23, through statistical testing of the T-test. The results of the T-test value are 6.140 and T-table is 1.999 with a significance of 0.000. Using the test criteria T-count T-table and if the significance α (0.05), then H0 is rejected, then in the calculation of the coefficient of determination it is known that the effect of office layout on teacher performance at MP UIN Jakarta is 38.2% while the remaining 61.8% is influenced by other factors not examined. However, it can be suggested for a madrasah to pay more attention to the arrangement and area of office space for the freedom of teachers to move. As well as paying attention to what needs are needed by teachers to improve the quality and performance of their teaching.
Manajemen Pengembangan Kurikulum Berbasis Pesantren
Authors: Nurkholis Nurkholis , Santosa Achadi Budi
Published: July 2023

The educational curriculum at Islamic boarding schools has an important contribution as an effort to develop an education system based on local wisdom. The development of the Islamic boarding school curriculum is expected to be able to provide a distinctive color in the dynamics of national education. This qualitative research uses a narrative literature review approach that originates from various manuscripts that discuss education, especially Islamic boarding schools. Data collection techniques were carried out through document review and confirmed through random observations at several sample pesantren. Data analysis used inductive techniques, starting with grouping data according to the theme, giving meaning to each part, and then summarizing descriptively. The results of the study show that the development of the Islamic boarding school curriculum still maintains a distinctive style, even though it is realized that the classical education model is difficult not to be influenced by modern education. Humanistic education is carried out as an effort to help students find their potential, so that they can develop naturally. Reconstruction of the curriculum is needed to realize social learning objectives, so that students are ready to live in society. This curriculum emphasizes the principles of cooperation and mutual respect in the learning process, so that a conducive learning atmosphere is created.
Análise bibliométrica da temática objetivos de desenvolvimento sustentável (ODS) no campo das ciências sociais aplicadas
Authors: Lima Anderson Antônio , Ribeiro Thiago de Luca Santana
Published: July 2023

Apesar da relevância da temática e dos impactos dos objetivos de desenvolvimento sustentável em todas as nações, a literatura não apresenta elementos que possibilitem identificar como o fluxo de pesquisa evoluiu ao longo do tempo, entender a evolução das pesquisas sobre a temática podem gerar novos insights e fornecer novas maneiras de implantar objetivos de desenvolvimento sustentável, neste sentido este estudo trata-se de uma análise bibliométrica que visa identificar como o domínio de conhecimento sobre objetivos de desenvolvimento sustentável surgiu e evoluiu no campo de ciências sociais. Trata-se de um estudo revisional, elaborado por meio de uma análise bibliométrica, esta técnica permite o mapeamento do surgimento e evolução de um campo científico, inclusive possibilita identificar os autores mais citados/influentes, instituições dos autores, redes de cooperação entre autores, recorrência de palavras chaves e estudos fronteiriços sobre um determinado tema (Zupic & Cater, 2015). A análise bibliométrica realizada possibilitou identificar por meio do mapa de cocitação a estrutura intelectual que norteia a evolução dos estudos sobre objetivos de desenvolvimento sustentáveis no campo de ciências sociais aplicadas. Esta técnica possibilitou a identificação de sete clusters, o cluster mais importante investigou a interpelação entre os 17 objetivos de desenvolvimento sustentáveis ODS. O mapa de pareamento bibliográfico realizado identificou sete clusters de estudos sobre responsabilidade social corporativa no campo de ciências sociais aplicadas.
 
Palavras-Chave: Análise Bibliométrica, Objetivos de Desenvolvimento Sustentável; Ciências Sociais Aplicadas
Determinação do pKa do indicador ácido-base Azul de Bromotimol
Authors: Andrade João Carlos de
Published: July 2023

As constantes de dissociação de ácidos fracos (ou seus valores de pKa) são parâmetros físico-químicos amplamente utilizados em diversas áreas de pesquisa e de interesse em vários ramos da ciência. Eles indicam a extensão da ionização de grupos ácidos em moléculas em diferentes valores de pH e desempenham um papel particularmente fundamental em estudos de procedimentos analíticos. Eles também encontram aplicação em muitos processos químicos e bioquímicos e podem ser considerados um fator chave para entender (e quantificar) fenômenos químicos associados à atividade biológica. Vários métodos instrumentais já foram utilizados para determinar os valores de pKa de ácidos fracos, mas a espectrofotometria UV-Visível, associada ou não a estratégias quimiométricas, é de longe a técnica mais simples, direta e que envolve os menores custos. A determinação espectrofotométrica do pKa de um indicador ácido-base é um experimento amplamente utilizado em laboratórios de ensino, pois são empregadas apenas soluções de fácil preparo, vidrarias de uso geral e equipamentos básicos de laboratório (como balanças, medidores de pH e espectrofotômetros). Este artigo detalha um procedimento simples, frequentemente utilizado para a determinação espectrofotométrica do pKa de indicadores ácido-base em laboratório de ensino, em que o indicador utilizado foi o azul de bromotimol e os dados experimentais foram obtidos por alunos de graduação durante uma aula de laboratório, sob a supervisão do autor. Os resultados concordam com os encontrados na literatura.
Hexagonal Boron Nitride Nanoparticles Prevent Neurodegeneration in Septic Rat Brain
Authors: ÇAKIR GÜNDOĞDU Ayşe , KAR Fatih
Published: July 2023

Sepsis, which develops with the triggering of an uncontrolled inflammatory response, causes multiple organ damage and dysfunction. Neuroinflammation occurring in sepsis causes varying degrees of deterioration in the central nervous system. Hexagonal boron nitride (h-BN) nanoparticles composed of boron and nitrogen have potential biomedical applications and are well tolerated by animals. Research has indicated that h-BN nanoparticles exhibit antioxidative characteristics. Although the anti-inflammatory properties of the boron present in them, the effectiveness of h-BN nanoparticles on systemic inflammation or neuroinflammation is unknown. Thus, the aim of this research was to investigate the potential protective benefits of h-BN nanoparticles against inflammation induced by lipopolysaccharide (LPS) in rat brains. An intraperitoneal 5 mg/kg dose of LPS was used to induce sepsis in Sprague Dawley rats. h-BN nanoparticles were given at 50 μg/kg and 100 μg/kg concentrations 24 h before LPS injection. To assess the prophylactic effect of h-BN nanoparticles in sepsis-induced neurodegeneration, besides measuring pro-inflammatory, oxidative stress, and apoptosis markers in brain tissues, the cerebral cortex and hippocampus were also examined histopathologically. Our ELISA results show that h-BN nanoparticles inhibit inflammation in the brain as evidenced by the reduction in LPS-induced increase in tumor necrosis factor-alpha (TNF-α) and interleukin-1 beta (IL-1β) levels. h-BN nanoparticles diminished the oxidative stress index and lowered cytochrome c and caspase-3 levels, components of the intrinsic apoptotic pathway. Our histopathological analyzes demonstrated that neuronal and neuroglial damage in the cerebral cortex and hippocampus was also prevented by the treatment of h-BN nanoparticles. These results implicated that h-BN nanoparticles could have a neuroprotective effect against sepsis-induced neurodegeneration through their anti-inflammatory, antioxidant, and anti-apoptotic properties.
Support from the government for SMEs in South Africa
Authors: Ramasimu Ntsieni , Majadibodu Morengwa Jacobeth , Ladzani Watson
Published: July 2023

This study intended to investigate how the Lephalale Local Municipality's small and medium companies (SMEs) are hampered by a lack of government support. This study also aims to demonstrate how SMEs face difficulties in surviving as a result of problems in the business environment. Consequently, the government of South Africa has programs to assist SMEs. The growth of SMEs is important for advancing innovation, wealth distribution, and employment. The majority of SMEs launch and maintain their businesses with their own money. By using a qualitative research approach and semi-structured in-person, phone, and email interviews to collect data, the goals of this study were met. There were 318 registered SMEs in the area. Using purposive sampling methods, data from operational enterprises with a lifespan of 0 to 5 years were gathered. Atlas TI 8 was used to evaluate the data. The primary conclusions of this study show that (i) small and medium-sized enterprises (SMEs) find it difficult to maintain their operations because they lack access to capital and business equipment. This fails if SMEs are not given the proper support. Because they lack the resources to compete with big companies, SMEs find it challenging. (ii) Small and medium-sized enterprises (SMEs) should think about enrolling in bookkeeping training and sending their staff to business training in order to network for the survival of the company. In order to assist SMEs in fulfilling the requirements for maintaining their enterprises, this study advises the government to examine present standards. With the right assistance, SMEs can create business plans and maintain operations, which will result in the creation of jobs, particularly for local communities. The government ought to think about mentoring and overseeing sponsored SMEs.
The state of crowdfunding in Africa and its potential impact: a literature review
Authors: Ismaila Bouba
Published: July 2023

The purpose of this review is to shed light on the current state of crowdfunding and its possible effects on African communities. The goal of this article is to give a narrative overview of how crowdfunding has evolved, along with trends, challenges, and potential effects on African communities. Despite recent advancements in the usage of mobile technology on the continent, the growth of crowdfunding based on internet platforms has been quite gradual. According to research, the success of crowdsourcing initiatives in Africa depends on a hybrid strategy that involves the "offline" network of backers. The majority of research concluded that the biggest barriers to the growth of crowdfunding in Africa were a lack of knowledge and trust in public institutions, lax laws protecting the rights of backers and ensuring transparency, as well as technology (internet connection). Also mentioned was the possibility that significant cultural aspects of offline crowdfunding, if taken into consideration, would make it easier for African business owners to adopt the practice. It has lagged behind other continents in the use of crowdfunding to raise money for small businesses or individuals, which could also help with financial inclusion in Africa, either directly for individuals or by sponsoring small enterprises. It is necessary to have a regulatory framework that promotes technological advancement while also reducing crime and fraud. Additionally, establishing platforms based on continents and creating synergies with existing financial actors would raise awareness, boost confidence, and whet interest in using them.
A deductive reflection on the modus operandi used to commit bank-associated robbery in South Africa
Authors: Thobane Mahlogonolo
Published: July 2023

In comparison to more common crimes like robbery of cash-in-transit, the idea of bank-related robbery—also known as "associated robbery"—has received very little attention. Even though the crime of bank-associated robbery has seen a large rise in instances and related losses, there is still little to no scientific research on the topic. Therefore, the purpose of this study is to investigate and characterize the modus operandi (MO) employed in bank-related robberies, a crime phenomenon that appears to be specific to South Africa. Eleven participants who are subject matter experts (SMEs) on the topic participated in in-depth qualitative interviews to learn more about the phenomena. According to the report, bank-related robberies fall into two primary categories: robberies that occur before cash deposits and those that occur after cash withdrawals. The police do not categorize bank-related robberies in the same way that the banking industry does, which is the biggest obstacle to preventative efforts. In order to address the aforementioned issue, this study adds to the body of knowledge on the subject in order to inform prevention initiatives. The results also show that carrying a lot of cash increases the risk of becoming a victim of crime for bank customers. Therefore, it is advised that bank customers carry the least amount of cash possible on them to make themselves less appealing to robbers.
The role of financial literacy on the growth outreach of South African microfinance institutions
Authors: Kuchena Emmanuel , Makoni Patricia Lindelwa
Published: July 2023

With the increased emphasis on financial inclusion by developing countries, the emergence, impact and sustainability of microfinance institutions (MFIs) is considered topical. This paper assesses the influence that financial literacy has on the growth outreach of MFIs, from a South African context. Using an online questionnaire, we collected data from 44 respondents, representing various MFIs in Limpopo, South Africa. In addition, interviews were conducted with four subjects from the regulatory body, MFSA. We applied panel data fixed effects regression, with binary logit component to measure relationships and effects of the variables under study. According to the results, there was strong consensus that financial literacy of MFI clients, proxied by loan portfolio education, and financial budgeting and investment training offered to MFI clients, improves overall MFI growth outreach, and MFI sustainability in the long run. The contribution of this paper is that, since microfinance institutions by mandate, pursue socio-economic goals, many are not geared towards being financially sustainable. However, with the drying up of grants, donor funds, subsidies and other capital injections into MFIs, it is important for them to implement alternative measures to ensure that their borrowers meet their repayment obligations timeously, hence improving institutional growth and sustainability.
Determinants of smartphones adoption and use at Kenya Airport Police Unit, Kenya
Authors: Sila Benedict M. , Mutuku Morrisson Kaunda
Published: July 2023

The Kenya Airport Police Unit has started using smartphones to deter crime, but there are still reservations about their potential impact on policing. The study sought to identify the factors that influence police officers' adoption and use of smart phone applications for crime prevention. The police officers assigned to the Kenya Airport Police Unit (1382) were the study's target group. For this study, a sample of 274 police officers was selected using a simple random sampling approach. The study was guided by the Mobile Technology Acceptance Model (M-TAM), which discovered that smartphones were useful instruments for crime prevention. Police officers discovered that programs such as Facebook, WhatsApp, Twitter, emails, and short text messages helped to prevent crime. The study suggests that tailored police smart phone applications be developed, as well as officer capacity training, to improve their utilization and help to crime prevention efforts.
The impact of inflation on firm value moderated by earnings quality in Indonesia
Authors: Isma Nisrin Naziha , Sutrisno T  , Rahman Aulia Fuad
Published: July 2023

This study examines the effect of inflation on firm value in Indonesia and uses earnings quality to moderate inflation’s effect on firm value. The aim of this study is to discuss whether earnings quality can weaken the effect of inflation on firm value. The sample of this study is consumer firm listed on the Indonesia Stock Exchange (IDX) from 2016-2021 with a total of 696 firm-years. Using EViews 9 as a statistical software to test the hypothesis, the results show that inflation harms the firm value, and also proved that earnings quality can weaken the effect of inflation’s negative effect on firm value. The findings provide insight that earnings quality can be a solution to reduce the effect of inflation on firm value. Overall, the findings support the previous studies that suggest inflation is an external factor that affects the firm value and can be solved by maintaining the quality of earnings.
Exploring the predictive factors of gen Z readiness for entrepreneurship
Authors: Soelaiman Lydiawati , Selamat Frangky , Puspitowati Ida
Published: July 2023

As one of the essential elements of the country's current economic development, Indonesia's government still supports entrepreneurial endeavors. Young entrepreneurs can only be developed with the help of universities. Students' entrepreneurial attitudes are anticipated to be shaped through the practical entrepreneurship program. As a foundation for student preparation to engage in entrepreneurial activity, this study investigates entrepreneurial intention. Students' entrepreneurial intents in Jakarta will be compared to three factors, including attitudes, subjective norms, and perceived behavioral control, that are based on the Theory Planned of Behavior. Purposive sampling was used to sample 120 students. Through the use of partial least squares structural equation modeling (PLS-SEM), variance-based SEM was employed to analyze the data. All variables are reliable and legitimate, according to the test results. The study's key conclusions show that while subjective norms have a minimal impact on entrepreneurial intention, attitude and perceived behavioral control have a positive and considerable impact. Entrepreneurial intent is also recognized to have a favorable and significant impact on readiness to launch a firm. The study's findings could be incorporated into entrepreneurship curricula at colleges to help the government's attempts to accomplish development objectives through entrepreneurial endeavors.
Ludwig Klages, Deep Ecology and the Concept of Friluftsliv in Nordic Countries
Authors: Belukhin N.
Published: July 2023

The article provides a brief overview of the views of philosophers Ludvig Klages, Arne Næss and Villy Sørensen, whose works revolved around the relationship between man and the environment. The article then proceeds to compare their philosophical ideas with the popular concept of friluftsliv which closely intertwines with the lifestyle as well as regional and national identity of Nordic countries. It is revealed that the common ground of both the philosophical constructions of deep ecology and the practice of friluftsliv is the close emotional connection between humanity and nature as its original environment. The analysis of development strategies of friluftsliv in Denmark, Norway and Sweden highlights the potential of friluftsliv phenomenon to be a conduit for fostering wide public solidarity on the ‘green’ agenda and promoting ecological consciousness and eco-citizenship in Nordic countries, which also corresponds to the idea of aesthetic, beautiful actions as formulated by Arne Næss. The conclusion is made that the systematically implemented practice of friluftsliv in Northern Europe can serve as an example of overcoming the conflict between radical environmental alarmism and skepticism and of making environmental care a part of everyday life and national consciousness. The article also notes the threat of right-wing radicalism and right-wing extremism employing the environmental rhetoric in order to increase their popularity among the younger generation. Despite local environmental initiatives conducted under the auspices of such organizations, their ‘green’ rhetoric primarily serves to reinforce their more traditional agenda of restricting immigration and eliminating ‘foreign and hostile’ elements from Nordic society. The conclusion emphasizes the broad potential for the study of national ecological cultures and identities, which could complement and broaden the existing research on the ‘green’ parties and mass environmental movements.
PinX1 Alleviates Atherosclerosis by Inhibiting MMP-9 Expression and p66shc-Mediated Oxidative Stress
Authors: Yao Yang , Zhang Qiaoling , Song Hongxia , Zhang Yukun
Published: July 2023

Atherosclerosis (AS) is an age-related disease. Mitochondria and telomere links have been considered to play important roles in AS. PinX1 is a potent and highly conserved endogenous telomerase inhibitor. However, the role of pinX1 in AS and its role in oxidative stress have not been reported. In order to investigate the role of pinX1 in AS, we established a classical AS mice model in the present work and increased pinX1 protein expression using pinX1 overexpression adeno-virus by tail vein injection. Then, red-oil O and HE staining were employed to evaluate the severity of AS. Serum lipid profile and oxidative stress were also detected by using its specific chemical testing kit. The results indicated that high-fat diet (HFD) markedly decreased pinX1 and increased p66shc protein expression, whereas overexpression of pinX1 protein expression in mice produced the opposite results. In addition, pinX1 significantly minimized plaque area and alleviated the abnormal serum lipid profile. By using Western blot and Biochemical assay kits, overexpression of pinX1 decreased p66shc and MMP-9 protein expression and reduced oxidative stress. This study showed pinX1 can inhibit p66shc, MMP-9, and related oxidative stress, pinX1 may be considered as a new candidate target for the treatment of AS.
Modified inertial-type subgradient extragradient methods for variational inequalities and fixed points of finite Bregman relatively nonexpansive and demicontractive mappings
Authors: Wang Cong-Shan , Ceng Lu-Chuan , Li Bing , Cao Sheng-Long , Hu Hui-Ying , Liang Yun-Shui
Published: July 2023

In this paper, we design two inertial-type subgradient extragradient algorithms with line-search process for solving the pseudomonotone variational inequality problems (VIPs) and common fixed-point problem (CFPP) of finite Bregman relatively nonexpansive mapping and a Bregman relatively demicontractive mapping in p-uniformly convex and uniformly smooth Banach spaces, which are more general than Hilbert spaces. Under mild conditions, we derive weak and strong convergence of the suggested algorithms to a common solution of the VIPs and CFPP, respectively. Additionally, an illustrated example is furnished to back up the feasibility and implementability of our proposed methods.
Theoretical Prediction of the Anti-Icing Activity of Two-Dimensional Ice I
Authors: Liu Si-Cheng , Liu Xiao-Yan , Li Yi-Ning , Guo Qing , Yu Xiang-Ting , YIn Yi , Jing Hao-Ze , Zhang Peng
Published: July 2023

Two-dimensional (2D) ice I is an atomic-level ice that is composed of two interlocked atom-ic layers saturated with hydrogen bonds. It has recently been experimentally observed but its properties have yet to be clarified. Accordingly, we theoretically studied the hydrophobic properties of 2D ice I. On the contrary, simulation of a hydrogen fluoride molecule on a 2D ice surface manifested that it destroyed the 2d ice structure and connected new hydrogen bonds with water molecules. Investigations of the interfacial effect between 2D and three-dimensional (3D) ice films indicated that the network structure of 2D ice was not de-stroyed by a 3D ice surface, as the former was saturated with hydrogen bonds. However, the surface of 3D ice reorganized to form as many hydrogen bonds as possible. Thus, the 2D ice film was hydrophobic and inhibited the growth of 3D ice. This shows that if 2D ice can be produced on an industrial scale, it could be used as an anti-3D-icing agent under low tem-perature.
Effect of Chest Physiotherapy with Threshold Valve in Hospitalized Adults with COVID-19 Pneumonia
Authors: Estela Julia , Sánchez Emilio José , Mateu Georgina , Fernandez Elena , Robert Eva , Pozo Silvia , Noray Mariona , Oliva Joan Carles , Caballero Fernanda , Luján Manel
Published: July 2023

Background: COVID-19 pneumonia caused by SARS-Cov-2 virus induces alveolar collapse and hypoxia that may become severe. The aim of the study is to analyze the effects of chest physiotherapy using a threshold valve in patients with acute respiratory failure due to COVID-19 pneumonia. Methods; Retrospective observational study, in hospitalized patients from March to May 2020. Breathing exercises were performed with a threshold valve of 10 cmH2O. Fraction of inspired oxygen, oxygen saturation, heart rate, respiratory rate and dyspnea were collected before and after the first session and at the end of the 5th day of chest physiotherapy treatment. Results: The final sample included 125 patients. Significant differences (p<0.01) were found in the pre-post intervention SpO2/FiO2 ratio (250±88.4 vs 275.6±97.5, p<0.001), reaching 354.4±110.2 after 5 days of therapy (p<0.001 with respect to baseline). Mean baseline respiratory, heart rate and level of dyspnea measure by the Borg scale did not change during the technique performance. In patient maneuvers with FiO2>0.4, the SaO2/FiO2 ratio increase was higher than in patients with milder severity (46.85 ± 77.69, p<0.01). Conclusions: Chest physiotherapy with a 10 cmH2O threshold valve is a safe and tolerated intervention with short-term improvement in oxygenation in patients with COVID-19 pneumonia.
The Methods of Determining Temporal Direction Based on Asymmetric Information of Optical Disk for Optimal Fovea Detection
Authors: Wibawa Helmie Arif , Sumiharto Raden , Harjoko Agus , Sasongko Muhammad Bayu
Published: July 2023

Accurate localization of the fovea in fundus images is essential for diagnosing retinal diseases. Existing methods often require extensive data and complex processes to achieve high accuracy, posing challenges for practical implementation. In this paper, we propose an effective and efficient approach for fovea detection using simple image processing operations and a geometric approach based on the optical disc's position. A key contribution of this study is the successful determination of the temporal direction by leveraging readable asymmetries related to the optical disc and its surroundings. We discuss three methods based on asymmetry conditions, including blood vessel distribution, cup disc inclination, and optic disc location ratio, for detecting the temporal direction. This enables precise determination of the optimal foveal region of interest (ROI). Through this optimized fovea region, fovea detection is achieved using straightforward morphological and image processing operations. Extensive testing on popular datasets (DRIVE, DiaretDB1, and Messidor) demonstrates outstanding accuracy of 99.04% and a rapid execution time of 0.251 seconds per image. The utilization of asymmetrical conditions for temporal direction detection provides a significant advantage, offering high accuracy and efficiency while competing with existing methods.
Study on Low Thermal-Conductivity of PVDF@SiAG/PET Membranes for Direct Contact Membrane Distillation Application
Authors: Xiang Jun , Wang Sitong , Chen Nailin , Wen Xintao , Tian Guiying , Zhang Lei , Cheng Penggao , Zhang Jianping , Tang Na
Published: July 2023

in order to enhance the separation performance and to reduce the heat loss of the transmembrane for membrane distillation, the thermal efficiency and hydrophobicity of the membrane distillation should be simultaneously enhanced. In this work, a PVDF/PET hydrophobic/hydrophilic membrane is prepared by non-solvent phase inducing method. Nanosized silica aerogel (SiAG) with high porosity is added to the composite membranes. The modifying effects and operating conditions on permeate flux and thermal efficiency in direct contact membrane distillation (DCMD) are investigated. Furthermore, the latent heat of vaporization and the heat transfer across the membranes are compared for SiAG addition, which indicates that the composite PVDF@SiAG/PET membranes display a great potential for distillation-separation application with high heat efficiency.
Short Review on Gender Studies in Central Asia
Authors: Rasulov Ikhtiyor , Juraev Zuhriddin
Published: July 2023

This advanced scholarly article examines gender equality, human rights, and women’s rights in Uzbekistan, focusing on domestic violence and women's leadership. It explores their relevance to the region and their connections to global human rights discussions and social justice theories. The first section addresses the widespread problem of domestic violence in Central Asia, emphasizing the need for comprehensive understanding and effective measures. The second section assesses women's progress in achieving gender equality and leadership positions in the Uzbek workplace, identifying research gaps and the impact of recent reforms. The study employs an observational approach, integrating raw data and social media information to analyze gender equality and research. Findings and recommendations draw from global human rights debates and social justice theories, contributing to future research on gender issues in Central Asia. Overall, this article offers a comprehensive analysis, contextualizing the issues within local and global perspectives and contributing to the dialogue on gender equality in a cultural context.
Functional Enhancement and Characterization of an Electrophysiological Mapping Electrode Probe with Carbonic, Directional Macrocontacts
Authors: Popa Radu Cristian , Serban Cosmin Andrei , Barborica Andrei , Zagrean Ana-Maria , Buiu Octavian , Dumbravescu Niculae , Paslaru Alexandru Catalin , Obreja Cosmin , Pachiu Cristina , Stoian Marius , Marculescu Catalin , Radoi Antonio , Vulpe Silviu , Ion Marian
Published: July 2023

Electrophysiological mapping (EM) using acute electrode probes is a common procedure performed during functional neurosurgery. Due to their constructive specificities, the EM probes are lagging in innovative enhancements. This work addressed complementing a clinically employed EM probe with carbonic and circumferentially segmented macrocontacts that are operable both for neurophysiological sensing ("recording") of local field potentials (LFP), and for test stimulation. The paper illustrates in-depth the development, that is based on direct writing of functional materials. The unconventional fabrication processes were optimized on planar geometry and then transferred to the cylindrically thin probe body. We report and discuss on the constructive concept and architecture of the probe, characteristics of the electrochemical interface deduced from voltammetry and chronopotentiometry, and the results of in vitro and in vivo recording and pulse stimulation tests. Two and three directional macrocontacts were added on probes having shanks of 550 and 770 m diameters and 10-23 cm lengths. The graphitic material presents a ~2.7 V-wide, almost symmetric water electrolysis window, and an ultra-capacitive charge transfer. When tested with 150 s biphasic current pulses, the interfacial polarization stayed safely away from the water window for pulse amplitudes up to 9 mA (135 C/cm2). The in vivo experiments on adult rat models confirmed the high-quality sensing of LFPs. Additionally, the in vivo-prevailing increase of the electrode impedance and overpotential are discussed and modeled by an ionic mobility-reducing spongiform structure; this restricted diffusion model gives new applicative insight into the in vivo-uprisen stimulation overpotential.
Study on Co-pyrolysis of Coal and Biomass and Process Simulation Optimization
Authors: Wang Biao , Liu Na , Wang Shanshan , Li Xiaoxian , Li Rui , Wu Yulong
Published: July 2023

In the end, this paper analyzed the economy from the investment in plant construction, raw material collection, product production and product sales. The resulting products include pyrolytic carbon, pyrolytic oil, pyrolysis gas. The results showed that when the treatment scale was 1 ton h−1, the pyrolysis plants with three loading modes will always be in a state of loss during the 20-year running time. When the processing scale was 9 ton h−1, the pyrolysis plant can be profitable in the first year. In the sensitivity analysis, the influence of three pyrolysis products on the total return on investment was explored. The results showed that the price change of pyrolysis oil has the greatest influence on the total return on investment (Total ROI) under the three loading methods, The price change of pyrolysis gas has minimal impact on the Total ROI. This study provides basic data and basis for the commercialization of coal-biomass co-pyrolysis technology and investment in plant construction.
Dual Token Blockchains
Authors: Dimitri Nicola
Published: July 2023

It is standard for blockchain platforms to issue native tokens, currencies, that users must own to operate within the platform. Some blockchains however decided to issue two tokens, a dual system, one typically for governance and the other for implementing functions on the blockchain, such as executing transactions or smart contracts. Therefore, the two tokens are used for different activities. Typically, owning the governance tokens gives right to receive the other token for free, as a reward for participating to the blockchain decision-making process. However, both tokens can also be traded on some exchange nodes, which means that platform functions could be implemented even without owning governance tokens. In the paper we discuss some economic fundamentals of dual-token blockchain platforms. In particular, we investigate the market relative attractiveness of the two tokens by introducing some simple numerical indicators, based on prices, traded and circulating monetary quantities. Such indicators, which are meant to reflect the platform view on the tokens’ market desirability, could be computed in real time and used to support the platform’s policy making.
Association of polymorphic variants of CYP2C19, P2RY12, ITGB3, ITGA2 and eNOS3 genes with high residual platelet reactivity while taking clopidogrel and acetylsalicylic acid at different terms of myocardial infarction
Authors: Pronko T. P. , Snezhitskiy V. A. , Stepuro T. L. , Kapytski A. V.
Published: July 2023

Aim.Study of the association of polymorphic variants of CYP2C19 (G681A), P2RY12 (H1/H2), ITGB3 (T1565C), ITGA2 (C807T), eNOS3 (T786C) genes with high residual platelet reactivity (HRPR) to clopidogrel and acetylsalicylic acid (ASA) at different terms of myocardial infarction (MI).

Material and methods. The study included 400 patients with MI aged 31-74 years, 317 (79,3%) men and 83 (20,7%) women. Platelet aggregation performed on days 1-2, 12-14 and 28-30 of MI, and genotyping by the polymerase chain reaction were analyzed using the STATISTICA 10.0 program.

Results.Differences were found in ADP-test 1-3 depending on the CYP2C19 (G681A) polymorphism, ADP-test 1 depending on the P2RY12 (H1/H2) polymorphism, ADP-test 2 depending on the ITGB3 (T1565C) polymorphism, ASPI-test 1 depending on the eNOS (T786C) polymorphism. The risk of HRPR to clopidogrel is higher in 681A CYP2C19 allele carriers compared to the G681 carriers throughout the entire observation period: initially odds ratio (OR) of 1,8 (1,14-2,88), p=0,012, on days 12-14 of MI, OR of 1,7 (1,08-2,68), p=0,023 and on days 28-30 of MI, OR of 2,3 (1,42-3,81), p=0,0008. The risk of HRPR to clopidogrel is higher in AA CYP2C19 genotype carriers compared to GG genotype carriers, on days 1-2 of MI (OR 6,5 (1,16-36,4), p=0,033), on days 28-30 of MI (OR 7,8 (1,26-48,0), p=0,027). The risk of HRPR to clopidogrel on days 1-2 of MI is higher in H2 P2RY12 locus carriers compared to H1 locus carriers (OR 1,5 (1,02-2,22), p=0,039). The risk of HRPR to ASA on days 1-2 of MI is higher in the 786C eNOS3 allele carriers compared to T786 allele carriers (OR 1,4 (1,02-1,96), p=0,036). Carriers of haplotypes of minor alleles of CYP2C19 + ITGA2 + P2RY12 + eNOS genes (OR 3,9 (1,13-13,65), p=0,032) and CYP2C19 + ITGA2 + eNOS genes (OR 5,1 (1,7214,96), p=0,0032) have higher risk of HRPR to dual antiplatelet therapy (DAPT) on days 28-30 of MI compared to the rest of patients.

Conclusion.The association of HRPR to clopidogrel with the CYP2C19 (G681A) polymorphism was found during the entire observation period, with the P2RY12 (H1/H2) polymorphism on days 1-2 of MI, with the ITGB3 (T1565C) polymorphism on days 10-12 of MI. The association of HRPR to ASA with eNOS (T786C) polymorphism was found on days 1-2 of MI. Minor allele haplotypes of the CYP2C19 + ITGA2 + P2RY12 + eNOS genes and CYP2C19 + ITGA2 + eNOS genes were associated with a higher risk of developing HRPR to DAPT on days 28-30 of MI.
Management of Bilateral Synchronous Knee Prosthetic Joint Infection in a Patient with Infected Heart Transplant
Authors: Jeong Seongho , Yang Ally , Rubin Lee E. , Arsoy Diren
Published: July 2023

Case:

A 74-year-old man presented with septic shock with infection of his heart transplant and bilateral prosthetic knee joints simultaneously. He underwent bilateral knee resection arthroplasties with placement of articulating spacers. At 3-year follow-up, the patient was alive and ambulating independently.

Conclusion:

This case represents the first report of bilateral hematogenous prosthetic knee infections associated with concomitant enterococcal endocarditis of a heart transplant treated successfully and definitively with radical debridement and placement of articulating spacer with regular implants.
Representaciones autoficcionales de Federico Fellini y de Marcello Mastroianni en la filmografía de Federico Fellini
Authors: Sabater Cuevas Pablo
Published: July 2023

El artículo introduce al fenómeno de la autodiégesis como instrumento para el estudio de la autoficción desde el personaje representado en la pantalla. Se focaliza en la filmografía de Federico Fellini y en las actuaciones que el mismo director realizó mediante su propia presencia. Igualmente se abordan las representaciones presentadas por el actor Marcello Mastroianni. Este análisis presenta una metodología con herramientas de análisis propias, originales y eficaces que se centran, por una parte, en la revisión bibliográfica de la biografía de ambos sujetos, el director y el actor, y en la documentación relativa a la elaboración de las diferentes películas objeto de estudio. Por otra parte, se analizan y se comparan los personajes mostrados en las distintas películas para encontrar semejanzas y diferencias entre ellos. Posteriormente se comparan conjuntamente todos los datos con el fin de establecer conclusiones. Los resultados muestran que Fellini se expone en su filmografía a través de su propia presencia mediante personajes centrados en el ámbito laboral. El ámbito íntimo, personal y privado es delegado a los personajes interpretados por Mastroianni. Además se certifica la utilidad del análisis de la actividad de otros departamentos de producción de la película para el estudio de la autoficción.
Instagram sin filtros
Authors: López Iglesias Matías , Martín-Sánchez Dario , Fernández Rodríguez Silvia
Published: July 2023

La manipulación fotográfica es un hecho normalizado, sobre todo por los más jóvenes. La era digital y el desarrollo de nuevas tecnologías han llevado a la implementación en los teléfonos móviles de cámaras integradas y nuevas aplicaciones. Entre estas aplicaciones se encuentran las redes sociales, que han cambiado los usos sociales de la fotografía y convirtiéndose en un medio de comunicación influyente en la sociedad. Este es el caso de la aplicación Instagram, que presenta un gran impacto respecto a la manipulación fotográfica. Se realiza un análisis de tres casos de fotografías manipuladas digitalmente. Demostrando que la manipulación excesiva de fotografías en perfiles de Instagram afecta de forma negativa en los usuarios que consumen esta red social. La información es recogida a través de una encuesta con una muestra compuesta por 70 personas de diversas edades. Este estudio tiene el objetivo de conocer las opiniones de los usuarios sobre la manipulación de la imagen en redes sociales y comprobar la relación que tiene el uso de Instagram y la salud de dichos usuarios. Como conclusiones se observa que, la mitad de los encuestados modifican sus fotografías, pero dos de cada tres se posicionan en contra de dicha manipulación.
Peningkatan Efektivitas Belajar-Mengajar Taman Pendidikan Al-Qur’an (TPA) di Desa Pagerejo
Authors: Ardhyantama Vit , Nurhayati Nurhayati , Erviana Lina , Widalestari Annisa , Syuri Aprilia , Pidialesta Kingkin , Krisnawati Krisnawati , Luhur Satrio Budi
Published: July 2023

Agama dan pendidikan merupakan satu keterkaitan yang tidak bisa dipisahkan, terutama pada pendidikan usia Sekolah Dasar (SD). Kegiatan ini dilaksanakan untuk menumbuhkan dan membangun jiwa islami pada anak usia dasar melalui pembelajaran agama di TPQ. Berdasarkan hal tersebut, tujuan dari kegiatan ini adalah untuk memaparkan: (1) metode pembelajaran yang digunakan di TPQ Nur Falaq (2) efektivitas pembelajaran Iqro’ maupun Al-Quran di TPQ Nur Falaq (3) faktor pendukung untuk perkembangan TPQ Nur Falaq (4) kontribusi yang diberikan untuk TPQ Nur Falaq melalui kegiatan ini. Waktu pelaksanaannya selama 2 hari, yakni pada Hari Sabtu, 9 Januari 2023 dan Minggu, 10 Januari 2023. Hasil dari pengabdian tersebut (1) metode yang kami terapkan adalah metode Integratif, Observasi, Ceramah, diskusi, Game/kuis, (2) Efektifitas dalam pembelajaran TPA masih dalam tahap berlanjut disertai dengan pembaruan-pembaharuan metode dalam pembelajaran di TPA, (3) faktor pendukung dalam pembelajarn TPA adanya tempat pembelajaran yang luas, bersih, nyaman serta didukuknya dengan media pembelajaran, (4) kontribusi yang kami berikan berupa proses pembelajaran dalam TPA yang menyenangkan dan kreatif menjadikan belajar para santri senang untuk mempelajarai agama Islam khususnya dalam membaca iqra dan Al-Qur’an serta dengan meceritakan kisah-kisah inspiratif para Nabi diharapkan dapat menambah semangat mereka dalam memperdalam Ilmu Agama.
Factors influencing HPV vaccine implementation in South Asia: A scoping review protocol
Authors: Rajkhowa Priyobrat , Pundir Prachi , Dsouza Sherize Merlin , Patil Divya Sussana , Narayanan Prakash , Brand Helmut
Published: July 2023

Introduction The human papillomavirus vaccine (HPV) is an effective investment in lessening the likelihood of contracting cervical cancer, lower healthcare costs, and reducing disability and death. However, low-income and lower-middle-income nations face multiple challenges in implementing the human papillomavirus vaccine at scale. Implementation of human papillomavirus vaccination for eliminating cervical cancer necessitates investigating the factors that impact the health system of these nations. Hence, this review will map the evidence on factors influencing the scaling up of human papillomavirus vaccination in South Asia. Methods The proposed scoping review will follow the steps given by “Arksey and O'Malley and Levac et al”. The search approach will follow McGowan et al. (2016) 's evidence-based manual for Peer Analysis of Electronic Search Strategies (PRESS 2015) for systematic searches”. Using a comprehensive search, the literature from 2006 onward will be identified from PubMed, CINAHL, EMBASE, Web of Science, and Scopus. The search strategy will include terms relating to the HPV vaccine and implementation. A predefined criterion for the inclusion and exclusion of studies will be adopted by three review authors independently to determine the eligible studies. The results will be narratively synthesized and examined in addition to being quantitatively presented to provide an outline. The review will be presented per the “Preferred Reporting Items for Systematic Reviews and Meta-analyses extension for scoping review (PRISMA-ScR)” guidelines. Conclusions/Discussion The evaluation is anticipated to map the barriers and enablers influencing the rollout of the human papillomavirus vaccine. Lessons learned from the South Asian countries where the vaccine has been implemented may contribute to aiding the implementation of the vaccine in India in an effective manner. Scoping review registration: The protocol was prospectively registered on the “open science framework”. The registration DOI is 10.17605/OSF.IO/QEWG3