bluuebunny/crossref_metadata_2025 huggingface dataset:
Le paradoxe, figure de la mémoire littéraire féminine de la Saint-Barthélemy. Marguerite de Valois, Charlotte Arbaleste et Renée Burlamacchi
Authors: Trotot Caroline
Published: December 2024

Marguerite de Valois, Charlotte Arbaleste et Renée Burlamacchi ont raconté la manière dont elles avaient vécu l’événement de la Saint-Barthélemy. Elles occupent évidemment des places différentes puisque la première des mémorialistes est une catholique qui appartient à la famille royale et assiste au massacre des Princes dans le Louvre tandis que les deux autres sont protestantes et vivent l’événement dans la ville. Pourtant les trois autrices usent de la figure du paradoxe pour donner forme à leur expérience. Cette figure leur permet de rendre intelligible un événement reposant sur de si fortes contradictions. Les trois autrices font ainsi apparaître leur conscience historique et dessinent également leur place. Renée Burlamacchi, enfant cachée témoigne discrètement pour des personnages populaires et révèle un talent de narratrice rarement souligné. Charlotte Arbaleste donne forme littéraire à la résistance à la « perplexité » et consent comme Abraham au sacrifice de sa fille plutôt que d’abjurer mais décide également d’agir. Marguerite de Valois apprend à manier l’ironie pour résister et dessine d’elle une figure qui s’oppose à celle de son frère Charles IX dans leur rapport avec Catherine de Médicis. Toutes donnent ainsi forme à leur conscience individuelle et nous permettent de comprendre des aspects du massacre de la Saint-Barthélemy concernant les victimes silencieuses.
La juste vengeance de Dieu et du roi. La Saint-Barthélemy comme argument en faveur de la violence religieuse dans les libelles catholiques zélés (1585-1629)
Authors: Goderniaux Alexandre
Published: December 2024

À travers une sélection de libelles publiés par les catholiques zélés durant trois séquences correspondant à autant de pics des conflits interconfessionnels français, cet article propose, d’une part, de reconstituer les stratégies présidant à l’exploitation de la mémoire de la Saint-Barthélemy à des fins d’argumentation et de positionnement politique et religieux, notamment en révélant quelles analogies sont effectuées entre cet événement et le contexte dans lequel paraissent les textes le mentionnant. D’autre part, faisant la part belle aux pratiques discursives, il montre comment le déploiement de telles stratégies a eu pour conséquence le façonnage de plusieurs interprétations a posteriori des événements de 1572, envisageant successivement son attribution à Charles IX, sa lecture comme la preuve d’une bénédiction divine, et enfin l’exploitation de la combinaison de ces deux motifs afin de légitimer la Saint-Barthélemy, voire de suggérer la prise d’initiatives comparables. À travers ce double questionnement, l’article montre que la Saint-Barthélemy a été considérée par les libellistes comme un épisode historique commun, exploitable, comme bien d’autres, à titre d’exemplum permettant d’effectuer des revendications politiques au présent grâce à des analogies avec le passé. Il révèle ensuite que l’instrumentalisation de sa mémoire permet de définir les catholiques zélés par un double rejet de l’édit de Nantes (tant en matière d’oubli que de cohabitation pacifique). Enfin, il montre que les conflits politiques et religieux du début du XVIIe siècle ont été pensés en liens étroits avec ceux des décennies précédentes, et invite les chercheurs à eux aussi les envisager comme tels.
Nouvelles de la nuit de la Saint-Barthélemy en Russie : choc à la cour d’Ivan IV
Authors: Chichkine Vladimir , Ryabov Sergey
Published: December 2024

L’article se propose d’étudier la réception des événements de la nuit de la Saint-Barthélemy en France et l’usage de cette nouvelle par le tsar russe Ivan IV le Terrible à partir de sa correspondance diplomatique. La réaction du tsar doit se comprendre dans le contexte de l’affirmation de l’État russe sur l’échiquier politique européen et surtout, plus précisément, dans celui de la concurrence pour le trône polonais. La condamnation de ce « massacre des Innocents » n’empêche pas pour autant le tsar de construire, ultérieurement, une relation épistolaire avec le duc Henri d’Anjou puis le roi Henri III.
Bartholomisirungen. Johann Fischart, l’atelier de Bernhard Jobin et les guerres civiles françaises (Strasbourg, 1575-1590)
Authors: Kammerer Elsa
Published: December 2024

Les guerres civiles de religion françaises ont suscité de très nombreuses réactions en terres d’Empire : pamphlets, feuilles volantes et journaux des deux bords y ont été traduits, édités et diffusés, en particulier dans l’atelier strasbourgeois de Bernhard Jobin. C’est là que paraît aussi, en 1575, augmentée en 1582, puis encore en 1590, la Geschichtklitterung de Johann Fischart, première transposition en langue étrangère du Gargantua de Rabelais. L’article contribue à l’exploration de deux chantiers encore en friches : il s’agit d’abord de renouveler l’interprétation de la Geschichtklitterung en évaluant mieux la manière dont Fischart y intègre des éléments de l’histoire française contemporaine ; il s’agit ensuite de mettre au jour un document méconnu de la réception, en terres d’Empire, de ces guerres, et en particulier de la Saint Barthélemy (que Fischart intègre à la langue allemande en créant le substantif Bartholomisirung), et de contribuer ainsi à une meilleure connaissance de la lecture, de l’interprétation et de l’utilisation qui en a été faite dans l’espace germanophone, y compris dans la littérature fictionnelle.
Voltaire et quelques « nuances » sur le massacre de la Saint-Barthélemy
Authors: Maira Daniele
Published: December 2024

Voltaire affirme que la « couleur dominante » du massacre peut être aperçue, mais que les « nuances » sont plus difficiles à cerner. Cet article se propose ainsi d’esquisser les quelques nuances restantes : l’importance symbolique de l’anniversaire du massacre, l’intérêt constant et cohérent que Voltaire nourrit pour cette page barbare de l’histoire, les effets de lexicalisation et, enfin, la sélection des victimes héroïques dans La Henriade. Le massacre des protestants n’évoque pas un passé lointain et oublié, mais un passé récent que la mémoire réactive régulièrement ; un lieu, un nom ou une journée suffisent pour raccourcir l’écart temporel et pour établir une continuité avec ce passé. La Saint-Barthélemy ou le récit de la Saint-Barthélemy est à l’origine de plusieurs scénographies auctoriales, en tant qu’historien, mémorialiste ou aède.
Le balcon de Charles IX, une scène légendaire entre histoire et littérature
Authors: Julian Thibaut
Published: December 2024

Image d’Épinal, la légende du roi Charles IX tirant depuis le Louvre sur son peuple durant la nuit de la Saint-Barthélemy s’est implantée dans l’historiographie et les œuvres littéraires françaises qui se sont emparées de l’événement dès la fin du XVIe siècle, notamment chez Agrippa d’Aubigné et Brantôme. Mézeray ou Bossuet la relaient au XVIIe. Mais c’est surtout aux XVIIIe et XIXe siècles qu’elle a rencontré un franc succès, en particulier grâce à Voltaire et aux pièces de théâtre critiquant le despotisme et le fanatisme religieux, selon une intention idéologique variable accentuée aux abords de la Révolution. Or en s’implantant massivement dans les représentations de la société postrévolutionnaire, de Mérimée à Zola en passant par Balzac, Michelet, Dumas et Flaubert, la légende, passée au crible de la critique, s’est émoussée à mesure que le spectre de la monarchie s’éloignait. Croisant des sources historiennes, des essais et des œuvres littéraires de fiction (roman, théâtre ou poésie), cette étude trace l’archéologie de la légende et l’interpénétration de son usage au fil des siècles, jusqu’au « grand partage » entre l’histoire-science et les œuvres d’imagination au seuil de la Troisième République. Il s’agit de retracer de manière synthétique l’évolution des usages de cette « scène du balcon », présentant Charles IX comme « méchant sans énergie » ou criminel pervers, donnant le spectacle scandaleux d’un roi déloyal, voire d’une institution monarchique éclaboussée du sang de la Nation.
Mémoire et actualité d’un massacre : la Saint-Barthélemy sous les plumes huguenotes du XVIIIe siècle
Authors: Bost Hubert
Published: December 2024

Cet article étudie les conditions dans lesquelles, au milieu du XVIIIe siècle, le massacre de la Saint-Barthélemy est réapparu dans les écrits des protestants français. Dans Le Patriote françois et impartial (1751), le pasteur Antoine Court réplique à l’évêque d’Agen qui s’est prononcé contre la tolérance des huguenots. Ce Patriote inspire trois autres textes : L’Accord parfait de la nature, de la raison, de la révélation et de la politique (1753), le Mémoire théologique et politique au sujet des mariages clandestins des protestants de France (1755) et la Lettre d’un patriote sur la tolérance civile des protestants de France (1756). Cet ensemble provoque les réactions de l’abbé Novi de Caveirac : un Mémoire politico-critique (1756) et une Apologie de Louis XIV et de son conseil sur la Révocation de l’édit de Nantes… avec une dissertation sur la journée de la S. Barthelemy (1758). Caveirac est à son tour attaqué par le pasteur de La Broue dans L’Esprit de Jésus-Christ sur la tolérance (1760), et Court de Gébelin y fait écho dans la Bibliothèque des Sciences et des arts. Ces derniers s’interrogent sur les raisons pour lesquelles un auteur catholique a entrepris de justifier la révocation de l’édit de Nantes et la Saint-Barthélemy. Ils discutent l’argumentaire historique de Caveirac, mais aussi le décalage stupéfiant entre son discours et les valeurs du « siècle éclairé » sous Louis XV. À ce corpus principal s’ajoutent des allusions à la Saint-Barthélemy faites par La Beaumelle dans L’Asiatique tolérant (1748), les références que La Beaumelle y fait en 1762 dans La Calomnie confondue écrite à l’occasion de l’affaire Calas, puis dans sa « Requête des protestants français au roi » de 1763, et Court de Gébelin dans ses Toulousaines (1763).
La Saint-Barthélemy dans la tourmente de l’affaire Dreyfus
Authors: Lestringant Frank
Published: December 2024

On s’interroge sur le caractère périodique de la Saint-Barthélemy, dont l’onde se propage de siècle en siècle, pour envisager l’un de ses retours les plus célèbres, celui qui s’est produit au déclin du XIXe siècle, au temps de l’affaire Dreyfus, non pas une véritable Saint-Barthélemy, mais son fantasme, rêve dément ou cauchemar insistant, présent aussi bien dans la bouche des antidreyfusards que des dreyfusards de la première heure. Ce rebond de l’affaire Dreyfus éclate en janvier 1898, avec le « J’accuse... » d’Émile Zola, suscitant dans le camp adverse un déferlement de haine. On a dit que l’affaire Dreyfus était l’acte de baptême des intellectuels en France. L’appartenance à une minorité religieuse a catalysé la prise de conscience. Le constat est évident pour les intellectuels d’origine juive, mais aussi pour les protestants, minorité intellectuelle alors toute-puissante dans les premiers âges de la république. Nationalistes et antidreyfusards stigmatisent de concert les deux minorités religieuses, rendues responsables de tous les malheurs de la France.
La Commune de Paris, Saint-Barthélemy du XIXe siècle dans les mémoires des Communards
Authors: Fix Florence
Published: December 2024

Les Communards écrivains ou journalistes après leur amnistie en 1880 mettent leur plume au service d’une rectification de l’histoire officielle et d’un récit de la répression, s’inscrivant dans ce que Jules Vallès nomme en exergue de L’Insurgé (1886) « la grande fédération des douleurs ». Il s’agit autant de justifier l’action politique a posteriori, de prétendre présenter des documents et des témoignages inédits que d’affirmer sa condition d’auteur, se distinguant des prisonniers de droit commun envoyés avec eux au bagne.Dans ces écrits, la Saint-Barthélemy est utilisée comme métaphore et comme emblème de la lutte fratricide absolue, du bain de sang outrancier. Au risque du raccourci et de l’équivalence hâtive (Thiers et Charles IX, le Louvre et les Tuileries) les mémoires des Communards multiplient les analogies, nous permettant de considérer la construction de l’événement, mais aussi la conception de l’historiographie ainsi en jeu. Le régime de l’anecdote et de la comparaison rapproche 1572 et 1871 pour éloigner 1793.
Push, Overload, and Exhaustion
Authors: Guo Zhiyin , Liu Ying , Gao Jing , Adams Matthew James , Kalinowska-Żeleźnik Anna
Published: December 2024

This paper studies college students' perspectives on social media discourse surrounding major international events and the effects on their psychological state and information-seeking behaviors. Through empirical research, this paper describes and analyzes the influences of “information push” from important international affairs, its inconsistent information quality, and excessive peer-to-peer sharing on users' emotional exhaustion and resistance to future social media engagement. Frequent push notifications cause interruptions that engender exhaustion. This paper identifies the “neglect” and “shielding” behaviors that can then result. Building on stressors previously identified in information overload on social media, this research furthers understanding of their interconnections. This paper develops a model that links social overload and system features with exhaustion, psychological resistance, social media discontinuation, and burnout. Corresponding countermeasures are put forward with proposed utility for social media users and the platforms themselves.
An Application of Machine Learning Models in Detecting Vietnamese Fake News
Authors: Le Thuan Ngoc , Nguyen Kim Ba Thien , Tan Vu Khanh Ngo
Published: December 2024

Nowadays, with the development of the Internet, publishing and sharing news has become very easy, and anyone can do it. Along with the increasing amount of information on the internet, besides official information, fake news continues to rise and spreads quickly across the network. Fake news has become a major societal problem, negatively impacting all aspects of economic, cultural, and social life. How to prevent the spread of fake news online is an urgent issue today. To help readers recognize whether news is trustworthy, this paper proposes using natural language processing techniques and machine learning models to detect fake news in posts on the social network Facebook in the Vietnamese language. After the training process, the resulting model can predict whether the news is real or fake. The model's evaluation results are presented according to popular machine learning metrics, and the best-performing model on the dataset used in this paper is the Light Gradient Boosting Algorithm – LGBM – with an accuracy of 88.21% compared to other models used in this paper.
Teacher Candidates' Perspectives on the Integration of Digital Tools in Teacher Training Programs
Authors: Yang-Heim Gui Ying Annie , Lin Xi
Published: December 2024

Digital tools are crucial in modern education for improving teaching practices and student engagement. While technology enhances learning, many teacher candidates still struggle to effectively integrate it into their teaching (Habibi et al., 2023). For instance, Seesaw is a widely used digital platform in K-12 classrooms but seldom explored in higher education. This study explores teacher candidates' views on integrating Seesaw into their learning processes, revealing benefits and challenges. The study is guided by Puentedura's (2010, 2014) SAMR model as a framework to evaluate and discuss the findings of integrating Seesaw in a literacy methods course. The study's insights aim to help teacher candidates, teachers, and educators enhance Seesaw's integration into teaching and learning. The goal is to ensure Seesaw enhances traditional teaching methods, meets learner needs, and maximizes the benefits of technology in higher education.
Management guidelines for pregnant women living with epilepsy: An integrative literature review
Authors: Birbal Sumeshni , Oosthuizen Frasia
Published: December 2024

Background: Epilepsy affects more than 50 million people worldwide, with a significant number of safety-related concerns arising in pregnant women. Precise management needs to include a vast array of stepwise protocols; however, no studies have been conducted to compare current South African guidelines to international norms.Aim: The aim of this integrative literature review was to identify discrepancies, if any, in the current protocols for treating pregnant women with epilepsy within the public sector of South Africa when measured against global standards.Method: An integrative literature review was conducted using the Whittemore and Knafl method. The following databases and search engines were used: PubMed, EBSCOhost, Science Direct, Medscape, African Journals Online, Cochrane Library, Google scholar, Google and MedlinePlus. The study included qualitative literature from all levels of evidence from 2006 to 2023. The data were evaluated using the PRISMA flow chart and analysed using the Cooper method. On completion of critical appraisal, 22 articles met the inclusion criteria and were analysed thematically.Results: The review identified several areas that can be enhanced to improve patient management and outcomes such as therapeutic drug monitoring and targeted dosing, folic acid supplementation, the use of antepartum vitamin K, high-resolution ultrasounds, elimination of sodium valproate in women of childbearing potential, monotherapy and endorsing frequent obstetrician visits.Conclusion: The study validated many differences between guidelines used in South Africa and internationally. Some of the prominent findings included areas focused on patient medication, screening, physician visits and pharmacovigilance.Contribution: The findings can be used to enhance and provide evidence-based recommendations in the areas that are not well developed within the current guidelines.
Revascularization of an acute right coronary artery long flap dissection with “Prolapsing knuckle wire technique”
Authors: Das Debasish , Mohanty Satyapriya , Kumar Abhinav , Banerjee Anindya , Deb Pranjit , Pramanik Subash
Published: December 2024

We present a rare case of revascularization of right coronary artery long flap dissection with novel prolapsing knuckle wire technique as the wire was repeatedly entering into the large medial dissection flap rendering the forward advancement of the wire impossible to cross the lesion. We negotiated the wire gently into the bottom of the dissection flap and pushed the wire gently so that the wire will ascend up and form a U loop inside the dissection flap. Further gentle advancement of the wire prolapsed the wire tip into the main lumen mimicking the fact that the dissection flap vomited out the wire into the main lumen. Keeping the tip of the wire in the main lumen, gentle pulling of the wire straightened the U loop, wire came out of the false lumen and gentle forward push with torque keeping the tip of the wire facing toward the lateral side the wire negotiated the microchannel present laterally and the lesion was crossed, predilated and successful coronary intervention was accomplished with Thrombolysis in Myocardial Infarction (TIMI) III flow. Our case is an interesting technique of guide wire negotiation in the presence of large dissection flap in acute coronary syndrome. Our case is also a rare illustration of a large spontaneous coronary dissection in an alcoholic.
Survival of a young male patient with catastrophic acute left main coronary artery occlusion and cardiogenic shock
Authors: Rao Lagaputi Rama , Nallapaneni Silpa Chowdari , Parvathaneni Naga Sri Haritha , Baig Akif Ahamad , Sahu Bikash
Published: December 2024

Total occlusion of the left main coronary artery (LMCA) is a rare but highly lethal event in acute coronary syndrome. It can lead to extensive myocardial infarction and hemodynamic instability. Despite advancements in percutaneous coronary intervention (PCI), mortality remains high. A 35-year-old male presented with chest pain, dyspnea, and hemodynamic instability. Diagnostic workup revealed LMCA thrombotic occlusion with extensive myocardial involvement and cardiogenic shock (CS). Prompt intervention, including thrombus aspiration, angioplasty, and hemodynamic support with intra-aortic balloon pump and venoarterial extracorporeal membrane oxygenation, was initiated. The patient’s condition gradually improved with comprehensive management, including pharmacotherapy and intensive care support. LMCA occlusion presents challenges due to its extensive myocardial distribution and high mortality rates, particularly when complicated by CS. PCI combined with circulatory support is crucial for restoring perfusion and improving outcomes. Achieving optimal flow and providing postprocedural care significantly impact patient prognosis. Rapid diagnosis and intervention are critical in LMCA occlusion with CS. A multidisciplinary approach incorporating advanced circulatory support and timely revascularization are the keys in improving patient outcomes. Comprehensive postprocedural care is essential for ensuring successful recovery and survival.
Utility of measurement of left ventricular global longitudinal strain by two-dimensional speckle-tracking echocardiography to predict cardiovascular events in patients with left ventricular systolic dysfunction: A pilot study
Authors: Malani Susheel Kumar , Nalawade Digvijay , Chigulapalli Sridevi , Kanitkar Shubhangi , Jadhav Ajitkumar , Gandhi Madhura
Published: December 2024

Introduction:

This pilot study explores whether left ventricular global longitudinal strain (LV GLS), measured by two-dimensional (2D) speckle-tracking echocardiography (STE), can predict cardiovascular events in patients with left ventricular systolic dysfunction (LVSD), including those with ischemic and nonischemic dilated cardiomyopathy, postvalve surgery, and chemotherapy recipients, compared to traditional parameters such as left ventricular ejection fraction (LVEF) and wall motion score index (WMSI).

Materials and Methods:

This retrospective study included 45 patients from a tertiary care center, with global longitudinal strain measurements taken between July 2022 and October 2023. Echocardiographic data, including LV-GLS, LVEF, and WMSI, were collected, alongside monitoring for cardiovascular events such as heart failure hospitalizations, cardiac mortality, and all-cause mortality.

Results:

In a study involving 45 patients (mean age: 57.9 years, 31.1% females), 17.8% experienced events. Patients with events exhibited significantly lower LV GLS values (P = 0.002), reduced LVEF (P = 0.002), and higher WMSI (P = 0.001). Mortality was higher in patients with LVEF <30% (62.5% vs. 18.9%, P = 0.026). Receiver operating characteristic analysis showed a significant area under the curves (AUCs) for LV GLS (0.846) and WMSI (0.860), while LVEF had a lower AUC (0.140). These findings suggest LV GLS and WMSI are valuable indicators for diagnosis and risk assessment, although more extensive studies are needed for validation.

Conclusions:

In this pilot study, LV GLS assessed through 2D STE shows promise as an effective predictor of cardiovascular events in LVSD, potentially surpassing traditional parameters. Further research and large samples are needed to validate its use in larger cohorts, offering a valuable addition to risk assessment in these patients.
Investigation of the effects of copper hydroxide (Cu(OH)2) nanopesticide on female and male populations of a wild-type and non-target model organism, Drosophila melanogaster Oregon-R, by in vivo longevity test
Authors: Uysal Handan
Published: December 2024

Copper hydroxide (a type of fungicide) is an innovative nanopesticide used in vineyard, olive and citrus cultivated copper-containing soils. However, nanopesticides, which replace traditional pesticides, can affect non-target organisms (vertebrates or invertebrates) as well as target organisms. This situation is an important risk factor, especially in terms of biodiversity. In this study, in vivo longevity testing was applied to male and female populations of Drosophila melanogaster Oregon-R to investigate whether there is such a risk. With the chronic application of Cu(OH)2 nanopesticide at different doses (10, 20, 40 and 80 ppm), it was observed that both maximum and average lifespan decreased in both populations compared to the control group (p
Pyrazoline compounds containing different groups: Design, synthesis and comprehensive molecular docking studies
Authors: Yalazan Halise , Koç Damla , Fandakli Seda , Tüzün Burak , Kantekin Halit
Published: December 2024

In the presented study, a series of methoxylated pyrazoline compounds containing amine (Py1-NH2 and Py2-NH2), tosyl (Py1-Ts and Py2-Ts), and nitrile (Py1-CN and Py2-CN) group were synthesized The structures of these compounds were clarified (by MS, FT-IR, and NMR analysis) through the use of mass spectral (spectrometer), FT-IR (spectrophotometer), and NMR (spectrometer) data. In order to examine the chemical properties of methoxylated pyrazoline derivatives theoretically, calculations were performed on the B3LYP, HF, and M06-2x methods using the 6-31++g(d,p) basis set. In addition, molecular docking calculations were performed to examine the interactions of methoxylated pyrazoline derivatives against cancer proteins. Afterwards, ADME/T was performed to examine the effects of methoxylated pyrazoline derivatives as drugs on human metabolism. According to the Gaussian calculations, the Py1-NH2 molecule is typically more active than other molecules. However, after the molecular docking calculations, the compounds' effects on cancer proteins were examined, and it was discovered that the Py1-NH2 molecule had more activity overall than the others. Following a comprehensive examination of the compounds' interactions with cancer proteins, the ADME properties of the molecules were examined. According to this analysis, it would not be detrimental to use the chemicals as drugs for human metabolism.
The potential use of Epilobium hirsutum L. in phytoremediation of zinc and an efficient method for in vitro propagation
Authors: Akanıl Bingöl Nüket , Akın Betül , Erdaş Nergiz
Published: December 2024

This study aimed to evaluate the capacity of Epilobium hirsutum L. (Onagraceae), a wetland plant, to accumulate and tolerate zinc (Zn) and its in vitro propagation potential. Root-shoot length, fresh weight, pigment, and protein content were analyzed in the plants grown in different Zn concentrations, including 0, 10, 20, 30, 40, 50, 75, 100,150, and 200 mg Zn/L. In the seedlings grown at 50 and 75 mg Zn/L concentrations, a reduction in the relative root length, shoot length, and fresh weight was detected. It was found that there was a negative correlation between pigment and protein contents of E. hirsutum and increased Zn concentrations of solutions. On the other hand, it was determined that a considerable amount of Zn was accumulated by E. hirsutum in its roots (10 598 mg Zn/kg DW). In tissue culture experiments, it was found that MS medium was effective for the germination of the plant (97%). When the growth parameters of plants grown in different concentrations of Gibberellic acid were evaluated, the highest growth parameters were obtained at 50 mg/L. It has been concluded that the most successful mediums on shoot development were 1.0BAP/1.0NAA and 1.0BAP/1.0IBA. The highest number of shoots per explant was 1.0BAP/1.0NAA (3.96). The longest root length was also determined on medium with 1.0BAP/1.0IBA (0.28 cm). Regenerated shoots were transferred to different concentrations of root mediums. It was concluded that MS medium with 1.0IBA has been superior for root formation compared to other hormone concentrations.
Investigation of the effects of lycorine and galanthamine extracted from Galanthus elwesii on viral and parasitic targets: An in-silico analysis and DFT Study
Authors: Gül Melek , Batı Ay Ebru
Published: December 2024

In this study, Density Functional Theory (DFT), ADME property analysis, and molecular docking simulations were employed to evaluate the electronic structure, antiviral potential, and antiparasitic effects of lycorine and galanthamine, two alkaloids extracted from Galanthus elwesii. We conducted a comprehensive study to assess the antiviral and antiparasitic potential of lycorine and galanthamine, two alkaloids whose biosynthetic production was significantly increased by zinc supplementation. DFT calculations revealed that lycorine has a lower Egap than galanthamine, suggesting higher reactivity and lower stability, enhancing its potential as a drug candidate. Pharmacokinetic profiling indicated that galanthamine (TPSA: 41.93 Å², logP: 0.797) has a lower total polar surface area (TPSA) and higher lipophilicity (logP) compared to lycorine (TPSA: 62.16 Å², logP: -0.268), indicating that galanthamine may possess superior absorption and permeability characteristics. ADME analysis also identified galanthamine with a lower AMES toxicity score, implying reduced mutagenic risk. A total of nine target proteins, representing viral and parasitic diseases Zika virus, malaria, leishmaniasis, and dengue, were chosen for molecular docking. Molecular docking studies demonstrated that lycorine exhibited superior binding interactions (-8.76 kcal/mol), particularly against Leishmania, and displayed stronger binding affinity across all selected target proteins. Despite galanthamine's lower toxicity profile, lycorine’s enhanced reactivity and stronger binding properties suggest its higher efficacy as a therapeutic candidate based on DFT and molecular docking results, while galanthamine shows potential based on its favorable ADME profile.
Destrukcija kao stimulans za nove oblike kreativnosti: Umjetnost i kultura u vrijeme opsade Sarajeva / Destruction as a Catalyst for New Forms of Creativity: Art and Culture During the Siege of Sarajevo
Authors: Mandić Asja
Published: December 2024

Through insight into the cultural events that marked the period of the siege of Sarajevo (1992-1995), which were a phenomenon not only because of the number of events held and the unprecedented attendance, but also due to their improvised creativity and innovation, the question arises as to how the city continued to live, not only in the face of the negation of everything that made it urban, but also in maintaining civilizational values. The art events enabled its citizens an escape from the everyday life of the siege, but also created places where social space was produced, places that revived the notion of the city as a place of meeting, social interaction and communication. Their emancipatory character in social, even political aspect, is being observed through the Foucault’s concept of “other places” or heterotopias, as well as through the creation of micro communities that played a significant part in revitalization of social body as well as humanizing the reality of war.
Slučajevi Vistilije i Emilije Lepide, primjeri prožimanja seksa i visoke politike u ranom Principatu / The Examples of Interweaving Sex and nd High Politics in the Early Principate - The Cases of Vistilia and Emilia Lepida
Authors: Mesihović Salmedin
Published: December 2024

During the reign of princeps Tiberius, 19th and 20th year AD. two judicial cases took place: “case Vistilia” and “case Aemilia Lepida”. The basic charge of both cases was sexual misconduct and adultery. The accused women belonged to the high Roman elite. Vistilia tried to evade the adultery law by losing her status as a matron and enrolling in prostitutes. The Senate prevented this by passing a corresponding law prohibiting women from knightly families from engaging in prostitution. Aemilia Lepida was attacked by her jealous ex-husband, and in addition to adultery, she was also accused of a number of other crimes. This process attracted considerable public attention in Rome, and the princeps himself was actively involved in it. Tiberius supported Qurinius, the accused’s ex-husband. Aemilia Lepida was defended by her brother, and she also had significant support from women from roman elite. However, during the process, her adultery was proven. Both women were punished by exile from Rome.
COVID-19 Döneminde 0-6 Yaş Çocukların Ev Kazası Geçirme Durumu ve Annelerin Aldıkları Güvenlik Önlemleri
Authors: Sökün Ayaz Demet , Yıldız Suzan
Published: December 2024

Amaç: Bu çalışma COVID-19 döneminde 0-6 yaş çocukların ev kazası geçirme durumları ve annelerin aldıkları güvenlik önlemlerinin değerlendirilmesini amaçlamıştır.
Gereç ve Yöntem: Kesitsel-tanımlayıcı tipteki bu çalışma 01.06.2022-31.08.2022 tarihleri arasında İstanbul ili Esenler ilçesinde yaşayan, 0-6 yaş çocuğu olan ve araştırmaya katılmayı kabul eden 113 anne ile yürütülmüştür. Veriler, Google Formlar aracılığıyla oluşturulan link ile internet ortamında elde edilmiştir. Verilerin toplanmasında, kişisel bilgi formu ve 0– 6 Yaş Çocuklarda Annenin Ev Kazalarına Yönelik Güvenlik Önlemlerini Tanılama Ölçeği kullanılmıştır.
Bulgular: Katılımcıların yaş ortalaması 35.1 ± 5.4 idi. COVID-19 döneminde çocukların %77.9’unun ev kazası geçirdiği ve en sık düşmenin (%46.6) yaşandığı belirlendi. Annelerin ev kazaları güvenlik önlemleri tanılama ölçeği puan ortalamasının orta düzeyin altında (96.0 ± 27.8) olduğu belirlendi. Pandemi döneminde lise mezunu, geliri giderinden az, çocuk sayısı 4 ve üzeri olan, erkek çocuğa sahip ve kendilerine ait odası olan çocukların anneleri ile ev kazaları konusunda eğitim almayan annelerin ölçek puanları anlamlı derecede daha yüksek çıktı (p
Investigation of the Postpartum Depression Levels at the 6th Postpartum Week of Mothers Who Gave Birth in One of the Eastern Provinces of Türkiye
Authors: Eminov Ayşe , Eminov Elmin , Ertem Gül
Published: December 2024

Aim: The aim of this study is to investigate postpartum depression (PPD) levels in postpartum women living in rural areas.
Material and Method: The study was carried out between 10.11.2022 and 10.11.2023 at a Training and Research Hospital in Ağrı province. The study was designed as a cross-sectional study and was conducted with 337 participants. In the study, the Data Collection Form and the Edinburgh Postpartum Depression Scale (EPDS) were used.
Results: In the study, the mean Edinburgh Postpartum Depression Scale (EPDS) score was found to be 11.51 ± 4.77 (min-max: 1-25). Age groups, place of residence, income and expense status, educational status, spouse's education status and mother's employment status, planned pregnancy status, number of pregnancies, number of stillbirths/miscarriages, postpartum weight, violence during pregnancy and presence of social support, starting work after birth. It was determined that there was a relationship between the time of birth, the time of holding the baby after birth, complications developing in the baby and the mother, and the scale score averages (p
Effectiveness of Different Exercise Approaches for Individuals with Chronic Low Back Pain Providing Primary Care to Multiple Sclerosis Patients
Authors: Karakaya Selin , Genç Hazal
Published: December 2024

Aim: Multiple Sclerosis (MS) need help with personal care due to symptoms like weakness, stiffness, and fatigue. Chronic low back pain often affects primary caregivers of MS patients. Our study aims to assess exercise efficacy in caregivers with chronic low back pain caring for MS patients.
Material and Method: Forty-one participants with low back pain for 12 weeks who were primary caregivers of MS patients were randomly divided into Pilates (n=20) and home exercise program (n=21). Visual Analogue Scale, Algometer, Oswestry Disability Index, Bakas Caregiver Outcome Scale, fingertip-to-floor test, 30-second sit-stand test and Beck Anxiety Inventory parameters were used on the participants. Assessments were conducted both prior to initiating treatment and following six weeks of exercise intervention.
Results: As a result of the applied treatment program, for both groups in the evaluation results; pain tolerance(p=0.001), bakas score (p=0.00), functionality (p=0.00) and anxiety (p=0.00) were also found to be improved. However, there was no statistically significant difference between the two groups when the groups were compared (p≥0.005).
Conclusion: Pilates exercise and the McKenzie home exercise program were shown to improve patients' pain and pain tolerance, functioning and anxiety. Moreover, these results underscore the importance of considering the individual preferences and needs of caregivers with chronic low back pain when making clinical treatment plans.
Yetişkin Bireylerde Eko-Anksiyetenin Sürdürülebilir Besin Tüketim Davranışları ile İlişkisi
Authors: Memiç İnan Cansu , Şarahman Kahraman Ceren
Published: December 2024

Amaç: Kesitsel olarak planlanan bu çalışmanın amacı yetişkin bireylerde eko-anksiyetenin sürdürülebilir besin tüketim davranışları ile ilişkisinin belirlenmesidir.
Gereç ve Yöntem: Çalışma verileri anket formu kullanılarak online platformlar aracılığı ile toplanmıştır. Anket formunda; genel bilgiler, Eko-Anksiyete Ölçeği ve Sürdürülebilir Besin Tüketim Davranışları Ölçeği yer almaktadır.
Bulgular: Çalışmaya katılan 432 bireyin %82.4’ü kadın olup ortalama yaş 31.9 ± 13.0 yıldır. Daha genç yaştaki bireylerde, öğrencilerde ve asgari ücretin altında gelire sahip olanlarda eko-anksiyetenin daha yüksek olduğu belirlenmiştir (p
The Curiosity Effect with Barnum Effect on the Tendency of Tarot Divination Addiction in Tarot Lovers in Semarang
Authors: Astuti Puji , Virgonita Mulya
Published: December 2024

This research aims to test and analyze the influence of curiosity and the Barnum effect on the tendency of tarot prediction addiction among tarot lovers in Semarng . This research is a correlational research carried out in Semarang from November 2023 to April 2024. The population of this research is tarot divination lovers in Semarang, where the population size is unknown with 92 research subjects. Samples were taken using snowball sampling technique. Data was collected by questionnaire. The dependent variable in this research is the tendency to get addicted to tarot predictions, while the independent variable is curiosity. Data analysis was carried out with SmartPLS 4.The results of the research show that (1) there is an insignificant influence of curiosity on the tendency to become addicted to tarot divination; (2) there is no significant influence of the Barnum effect on the tendency to become addicted to tarot predictions; (3) there is a significant influence of curiosity on the Barnum effect; (4) there is an insignificant influence of curiosity on the tendency to become addicted to tarot divination through the Barnum effect. The influence/contribution of the curiosity variables , Barnum effect on the tendency to become addicted to tarot predictions is 73%, while the other 26.2% is influenced by other variables outside this research
Determinan Financial Distress: A Study on The Property and Real Estate Sector in The Indonesia Stock Exchange
Authors: Marcella Rini , Utami Wiwik
Published: December 2024

The property and real estate sector plays a crucial role in the Indonesian economy but faces significant risks of financial distress. This study aims to identify the determinants of financial distress within this sector, focusing on companies listed on the Indonesia Stock Exchange between 2018 and 2022. The research examines the effects of profitability, liquidity, leverage, interest rates, and inflation on financial distress. Using a quantitative approach, this study applies statistical techniques and regression analysis to secondary data from various property and real estate companies. The findings reveal that: (i) profitability has a negative impact on financial distress, indicating that lower profitability increases the likelihood of financial difficulties; (ii) liquidity also shows a negative relationship with financial distress, meaning reduced liquidity elevates financial risk; (iii) leverage negatively influences financial distress, suggesting that higher debt levels exacerbate financial instability; (iv) rising interest rates contribute to financial distress by increasing borrowing costs, thereby straining company resources; and (v) inflation worsens financial distress by eroding purchasing power and dampening property demand. This study provides valuable insights for stakeholders, including investors and policymakers, to enhance their understanding of financial risk management in the property and real estate sector. The novelty of this research lies in its specific focus on a critical period and sector within the Indonesian economic landscape, addressing key areas of concern for financial stability
Waste Management of Innovation Production Through The Printing Block Printing Plate Workshop Using The Design Thinking Approach
Authors: Hafildah Nora , Widiatmoko Soewardikoen Didit , Azhar Hanif , Nur Hadiansyah Mahendra
Published: December 2024

The waste problem in Indonesia is a problem that has not been resolved to date; this hurts the surrounding environment, one of which is 23.3 million tonnes annually produced from 202 districts or cities, of which only 15 are appropriately managed. 6 million tons annually. Therefore, it is necessary to process plastic waste to minimize the accumulation of plastic waste and its impact on the environment (Amanullah. G, 2023). Olah Plastic is one of the MSMEs located in Bandung that processes plastic waste into products. However, Olah Plastic has a problem in the form of remaining unprocessed production waste, so product innovation is needed that can minimize production waste and activities that can increase public knowledge about processing. plastic waste. The results of this research are block printing plates made from the remaining waste from Olah Plastic production, where the printing plates will be used as media in workshops to increase public awareness regarding the negative impact of plastic waste on the environment, which still has selling value
The Impact of Traffic Congestion on the Mental Health of Civil Servants: A Case Study of Ministry of Transportation Employees in the Greater Jakarta Area
Authors: Fitria Brilianti Dani , Rokhim Abdul , Basuki Ahmad
Published: December 2024

This study aims to investigate the psychological effects of prolonged traffic congestion on civil servants working in the Ministry of Transportation in the Greater Jakarta Area. As one of the most densely populated regions in Indonesia, Greater Jakarta experiences severe daily traffic, which has the potential to exacerbate mental health issues. The research employed a quantitative approach through a structured survey distributed to 102 respondents. The respondents were classified into three categories of mental health disorders: high, moderate, and low, based on validated psychological scales. The results indicated that 51.20% of respondents experienced severe mental health disorders, while 39.21% reported moderate disorders, and 8.82% exhibited mild symptoms. Emotional regulation difficulties, anxiety, and mood disturbances were significantly related to traffic exposure. The study recommends implementing flexible work arrangements, improving public transportation infrastructure, and providing mental health support programs to mitigate the adverse effects of traffic congestion on civil servants. These findings highlight the need for urgent policy interventions to promote the well-being of public servants in urban settings, particularly those affected by chronic congestion.
Innovation In Patchwork Waste Processing Using Fabric Manipulating Techniques And Design Thinking Approach
Authors: Madani Aisyiyah Wulan , Widiatmoko Soewardikoen Didit , Azhar Hanif , Nurhadiansyah Mahendra
Published: December 2024

Fashion waste is a global concern due to its large production volume. Therefore, waste management is a major concern in the industry to reduce negative impacts on the environment. The case study in this study is on a garment factory on Jalan Tamim. The waste produced by this garment needs to be considered in environmental management on Jalan Tamim Bandung. It highlights the urgency of implementing more sustainable production practice innovations by utilizing fabric scraps. The design approach method is used to provide a deep understanding of the problem's urgency that can produce design solutions with the Design Thinking stages, namely, emphasizing, defining, ideating, prototyping, and testing. The design results are expected to be an alternative strategy for utilizing fabric scraps in the context of sustainable fashion using fabric manipulation techniques
GENTRIFICAÇÃO E NECROPOLÍTICA: uma observação dos processos de violência e ocupação da cidade do contexto no bairro São Pedro em Chapecó - SC
Authors: Cerutti Saulo , Renk Arlene Anélia
Published: December 2024

A análise dos conflitos e das violências de determinada sociedade não pode ser destacada dos fenômenos criadores, fazendo com que a identidade coletiva e a historicidade da estrutura comunal sejam parte integrante das dinâmicas sociais. O estudo das violências entre crianças e adolescentes no Município de Chapecó foi o fato gerador da análise dos processos de criminalização e do fenômeno urbanismo social e da qualificação ambiental como instrumentos de gestão social direcionando a investigação para o Bairro São Pedro em Chapecó, tanto pelo contexto histórico-formativo quanto pelo preconceito instalado pela estigmatização criminal. Por meio de levantamentos bibliográficos, que possibilitaram a compreensão da formação histórica da comunidade, em etnografias e publicações jornalísticas sobre o campo de estudo, aliado às percepções de membros das forças policiais, estabelecemos como objetivo da pesquisa compreender o tecido em que se desenvolvem as relações de violência, vulnerabilidade e ocupação espacial nas conexões entre o direito à cidade e a gestão social por parte do Estado e da exploração econômica. Notamos uma tendência necropolítica na atuação do Estado e da iniciativa privada — em especial com a atividade especulativa imobiliária — no controle das violências, com um processo consequente de gentrificação, não resolvendo as condições de vulnerabilidade da comunidade atingida, mas realocando habitações carentes e ampliando os processos de segregação para novas fronteiras de vulnerabilidade.
QUEM PARTICIPA DO JOGO DA BRANQUITUDE? Do perigo ao privilégio amarelo
Authors: Komino Aline Chima , Yamamoto Gabriel do Carmo , Ichikawa Elisa Yoshie
Published: December 2024

Partindo de uma revisão histórica, neste ensaio, propomos uma reflexão sobre o conceito de amarelitude, defendendo a ideia de que é essencial incluir a amarelitude na análise do racismo estrutural, para compreender a complexa relação racial no Brasil. Primeiro, voltamos na história, citando alguns pontos importantes da imigração chinesa, sul-coreana e japonesa. Em seguida, trazemos os significados e simbologias do que seria o perigo amarelo, ao mesmo tempo em que questionamos a construção do estereótipo de uma minoria modelo. Por fim, articulamos essas transformações na narrativa histórica para debater esse não-lugar ocupado pelas pessoas amarelas dentro do jogo da branquitude. Esperamos, com este manuscrito, contribuir para uma maior compreensão das relações raciais, despertando uma maior conscientização racial por parte das pessoas na sociedade brasileira.