bluuebunny/crossref_metadata_2025 huggingface dataset:
EDUCAÇÃO MERCADORIA? EMPRESARIAMENTO? DEFENSORES DA EDUCAÇÃO COMO DIREITO PÚBLICO, UNI-VOS!
Authors: Colares Anselmo , IMBIRIBA SOUSA COLARES MARIA LÍLIA
Published: October 2023

A educação como direito público que se consolidou a partir das lutas políticas da classe trabalhadora está seriamente ameaçada nesta fase do capitalismo financeiro. Como resultado de pesquisa bibliográfica demonstramos  que a grave crise estrutural somada aos problemas decorrentes da conjuntura de crise sanitária e política no Brasil levou à intensificação das investidas sobre a educação, entendida como mercadoria à disposição de grupos empresariais que controlam os processos de oferta de serviços e produtos, precarizando o trabalho e promovendo o desmonte de políticas públicas.
Palavras-chave: empresariamento na educação; financeirização; educação como mercadoria.
Penentuan Kandungan Etanol dalam Makanan dan Minuman Fermentasi Tradisional Menggunakan Metode Kromatografi Gas
Authors: Hermanto Dhony
Published: October 2023

Determination of alcohol content in food and beverage is needed for halal verification. Ethanol content in various food and beverage traditional products from fermentation was determined using the gas chromatography method with ethanol as standart and n-buthanol as internal standart. As comparison, measurement using alcohol meter were conducted. The GC measurement result were also compared with alcohol content printed on the packaging (value declared by the producer). The result showed that linear range in ethanol concentration was 1-10% with correlation coefficient (r) of  0.9984, indicated that GC has excellent linearity. Limit of detection was  0,5 ng, coefficient  variance (CV) was  ≤ 2%,  accuracy (K) was ≤ 5% and recovery was > 2%, indicated that  GC method has high sensitivity, accuracy, validity and recovery. Alcohol content in beer samples listed in the packaging was confirmed with GC measurement results. Anova test results showed  that the GC methods with  alcohol meter methods did not differ significantly so that the GC and alcohol meter methods can be used as a good alternative in determining the ethanol content in fermented foods and beverages as a support in halal verification.
Formulasi pasta gigi hidroksiapatit dari limbah tulang ikan tenggiri (Scomberomorus guttatus)
Authors: Hernawan Aldi dwi , Anggresani Lia , Meirista Indri
Published: October 2023

Provinsi Jambi memiliki 45% permasalahan gigi dan mulut. Permasalahan gigi dan mulut dapat dicegah dengan cara menyikat gigi dua kali sehari menggunakan pasta gigi. Pasta gigi diformulasikan menggunakan  hidroksiapatit (HAp) yang berasal dari limbah tulang ikan tenggiri yang memiliki unsur utama kalsium. Metode Tulang ikan tenggiri direndam dengan NaOH dan aseton. Selanjutnya dilakukan kalsinasi pada suhu 800°C hingga didapatkan bubuk CaO. Bubuk ini dianalisa dengan XRF untuk mendapatkan oksida logamnya. CaO direaksikan dengan (NH4)2HPO4 dengan mol Ca/P 1,67 kedua larutan dicampurkan dan dipanaskan 90°C selama 1 jam. pH diatur hingga 12 dengan menambahkan NaOH. Selanjutnya dilakukan kalsinasi pada suhu 900°C. Selanjutnya bubuk dianalisa XRD dan SEM. Hidroksiapatit (HAp) diformulasikan menjadi pasta gigi dengan konsentrasi 45%, 50% dan 55%. Pasta gigi dievaluasi organoleptis, homogenitas, ketinggian busa,daya sebar,pH serta hedonik. Hasil analisa XRF didapatkan senyawa CaO sebanyak 49,911 %. Hasil analisa XRD pada mol Ca/P 1.67 didapatkan senyawa hidroksiapatit (HAp) yang sesuai dengan standar ICSD No 96-900-1234. Semua pasta gigi yang diformulasikan memenuhi persyaratan pasta gigi yang baik. Hidroksiapatit (HAp) dapat diformulasikan menjadi pasta gigi dengan konsentrasi yang baik adalah 45%.
Changes in lactic acid bacteria and quality of gac yoghurt supplemented with carbohydrate sources during chilled storage
Authors: Kulsut Nirawan , Kapo Palita , Boonreang Supot , Panyoyai Naksit
Published: October 2023

Gac yoghurt is formulated by mixing gac juice with cow milk and probiotics to form a thick yellow fluid. The research objective was to study the effect of carbohydrate sources (inulin, honey, sucrose, fruit syrup, and sucrose) on lactic acid bacteria remaining after the chilled storage for 28 days. The gac yoghurt was analyzed with physicochemical and sensory characteristics. The experimental design was a Complete Randomized Design (CRD) with eight parameters (total soluble solids, pH, lactic acid content, syneresis, texture, colour, lactic acid bacteria survival, and sensory evaluation). The results showed that in the presence of honey, gac yoghurt had a higher lactic acid count than other treatments throughout 28 days of storage. The lactic acid growth was observed in the first two weeks, then it was almost constant in the third week and levelled off at the end of storage. The addition of carbohydrates resulted in a lower pH than a control. It increased total soluble solids, titratable acidity, and syneresis effect. Gac yoghurt with inulin enrichment kept for 28 days showed a firmer texture and lighter than the rest. However, sensory results showed that gac yoghurt with sucrose was the most preferred formulae based on the average Hedonic scores followed by the yoghurt fermented with honey, inulin, and fruit syrup, respectively.
Strategi Guru Dalam Menerapkan Kegiatan Literasi Digital di Sekolah Dasar Negeri 47/IV Kota Jambi
Authors: Wardani Riska , Budiono Hendra
Published: October 2023

Abstrak
Penelitian Ini bertujuan untuk mendeskripsikan strategi guru dalam menerapkan kegiatan literasi digital di sekolah dasar di kelas tinggi Sekolah Dasar Negeri 47/IV Kota Jambi.Penelitian ini dilaksanakan di Sekolah Dasar Negeri 47/IV Kota Jambi pada 01 September 2022. Penelitian ini menggunakan pendekatan kualitatif dengan jenis penelitian fenomenologi. Data dalam penelitian ini diperoleh melalui kegiatan observasi, wawancara dan dokumentasi.Hasil penelitian menunjukan bahwa strategi yang dilakukan oleh guru dalam menerapkan kegiatan literasi digital di kelas tinggi Sekolah Dasar Negeri 47/IV Kota Jambi siswa mendapatkan informasi yang valid. Dengan strategi yang telah digunakan oleh guru dapat meningkatkan keingintahuan, meningkatkan keberanian bertanya siswa.
Penerapan Model Pembelajaran Giving Question and Getting Answer untuk Meningkatkan Aktivitas Belajar Siswa PPKN di Kelas V Sekolah Dasar
Authors: Putri Wanda oktalia , Anderson Irzal , Doa Restuti Putri
Published: October 2023

Penerapan model pembelajaran yang kurang efektif dan inovatif dapat menyebabkan rendahnya aktivitas belajar siswa, sehingga diperlukan model pembelajaran yang mampu memotivasi siswa untuk meningkatkan aktivitas siswa dalam pembelajaran khususnya pada pembelajaran PPKn. Penelitian ini bertujuan untuk menganalisis aktivitas belajar  siswa  kelas  V semester  genap  setelah  diterapkannya  model  pembelajaran question and getting answer. Penelitian ini merupakan penelitian tindakan   kelas (PTK) yang dilaksanakan dalam dua Siklus. Subjek penelitian ini adalah seluruh siswa kelas V yang terdiri dari 25 orang siswa, sedangkan objek penelitian ini  adalah  hasil  keaktifan belajar siswa. Data hasil belajar siswa dikumpulkan  melalui  lembar observasi  pada  setiap  akhir  siklus.  Data yang telah dikumpulkan tersebut dianalisis dengan    menggunakan   analisis kuantitatif. Hasil penelitian ini menunjukkan peningkatan keaktifan belajar peserta didik terlihat dari hasil observasi pada siklus I keaktifan belajar peserta didik 55%. Meningkat pada siklus II menjadi 85,24% kategori sangat baik (A). Berdasarkan temuan hasil penelitian maka dapat disimpulkan tindakan yang diberikan melalui penerapan model pembelajaran Giving Question and Getting Answer berhasil dalam meningkatkan aktivitas belajar siswa di SDN 78/I Teluk Ketapang, Kecamatan Pemayung, Kabupaten Batanghari
PERSPECTIVE OF ENGLISH TEACHERS ON NATIONAL ASSESSMENT (MINIMUM COMPETENCY ASSESSMENT, SURVEY OF CHARACTER AND LEARNING ENVIRONMENT)
Authors: Zuri Tella  Amy Novera Afan
Published: October 2023

This research is aimed to discuss about perspective of English teachers on National assessment in term of minimum competency assessment, survey of character and survey of learning environment as three main components of National assessment. This qualitative research was using interview with five English teachers in Jambi Province as research participants. Pseudonym were used in this research to protect the privacy of research participants. Five participants will be identified as T1, T2, T3, T4 and T5. The results of this study indicated that only T1 had complete knowledge and comprehension about National assessment. Three of five English teachers (T2, T3 and T4) had knowledge and comprehension about the National assessment in general, but did not have specific knowledge and comprehension of the National assessment, while one of English teachers (T5) had no idea and did not understand at all related to knowledge and comprehension of the National assessment as a comprehensive evaluation program. All participants (T1, T2, T3, T4 and T5) have never attended seminar, training and any form of socialization about National assessment. It can be concluded that there is a lack of optimal socialization regarding the National assessment conducted by the government for English teachers and all parties in this evaluation program such as headmaster, teachers and student. It is causing all research participants (T1, T2, T3, T4 and T5) still do not have sufficient knowledge and comprehension of the National assessment and its implementation.
Metodologías para la sostenibilidad de los proyectos
Authors: Motta – Sanjuan Yesenia
Published: October 2023

Cuando se habla de proyectos hoy en día, también aparece un componente relevante para su gestión como lo es la sostenibilidad. Temática que agrupa diversos aspectos entre los que se encuentran las metodologías, mediciones y los modelos, los cuales dan paso a evaluar los procesos sostenibles que desarrolla todo líder de proyectos, por lo que suelen ser técnicas y herramientas complementarias que miden el impacto de los procesos dentro de las dimensiones social, económica y ambiental. Bajo este enfoque, es presentado este artículo de revisión, donde se trata de estudiar y analizar el mundo de los proyectos en atención a su desarrollo en el marco de la generación de valor dentro de un entorno globalizado y dinámico. Concretamente es puntualizada la gestión de proyectos en función del cumplimiento de los estándares de sostenibilidad basados en principios de responsabilidad social que reflejan la contribución de los mismos dentro del ejercicio de cooperatividad y desarrollo general del sistema. La idea entonces, es abordar la sostenibilidad desde la planificación, dirección y control de los proyectos, en donde se constituye como un elemento clave para la gestión apoyada en métodos.
ANALISIS PENDAPATAN DAN KELAYAKAN USAHATANI PADI SAWAH DI DESA SRITABAANG KECAMATAN BOLANO KABUPATEN PARIGI MOUTONG
Authors: Pertiwi Dewa Ayu Putu , Lamusa Arifuddin , Malik Shintami R.
Published: October 2023

Penelitian ini dilakukan  untuk mengetahui besarnya pendapatan dan tingkat kelayakan usahatani padi sawah di Desa Sritabaang. Penelitian ini dilakukan secara sengaja (purposive). Penentuan responden dilakukan dengan menggunakan metode sampel acak sederhana (Simple Random Sampling). Penentuan jumlah sample dalam penentuan ini menggunakan rumus slovin dengan jumlah sample yang di ambil sebanyak 28 KK dari 125 KK petani padi sawah dengan tingkat kesalahan sebesar 15%. Analisis yang digunakan dalam penelitian ini adalah analisis pendapatan (π) dan analisis kelayakan (R/C). Hasil analisis menunjukan bahwa rata-rata pendapatan petani responden di Desa Sritabaang selama satu kali musim tanam yaitu sebesar Rp. 20.086.039/1,34 ha/MT atau 14.997.576 ha/MT. Hasil analisis R/C yang di peroleh sebesar 1,93 yang artinya bahwa setiap pengeluaran sebesar Rp. 1 akan memperoleh penerimaan sebesar Rp. 1,93 dan hasil dari analisis tersebut juga menunjukan bahwa usahatani padi sawah di Desa Sritabaang layak untuk diusahakan.
Oral Immunotherapy for cashew nut and peanut allergy in children -- a retrospective single-center study
Authors: Breiding Maria , Soomann Maarja , Roth Michèle , Trück Johannes , Enders Felicitas Bellutti
Published: October 2023

Background Oral immunotherapy (OIT) is increasingly used for the
treatment of childhood food allergies, with limited data available on
cashew nut allergy OIT. This study investigated the safety and
feasibility of cashew nut OIT, comparing it with peanut OIT. Methods We
retrospectively analyzed cashew nut (n=24) and peanut (n=38) OIT cases
initiated between 2018 and 2022. Two different starting protocols were
used, and nut intake was then incrementally increased by 20-30% every
two weeks to reach a maintenance dose of 1 g of nut protein. After
consuming the maintenance dose regularly for 18-24 months, a second oral
food challenge was performed. Patients who passed this challenge were
considered desensitized. The safety of the therapy was evaluated based
on the frequency and severity of adverse reactions during the up-dosing
phase. Results Over the study period, 33% of cashew nut-allergic and
63% of peanut-allergic patients experienced mild to moderate side
effects. Severe reactions occurred in five peanut-allergic children with
high initial IgE levels. Six patients with peanut and none with cashew
nut OIT, were discontinued due to side effects. The mean duration to
reach the maintenance phase was longer for children with asthma or
another food allergy. Among children undergoing the second challenge,
desensitization was achieved in 88% of cashew nut and 69% of
peanut-allergic patients. Conclusion Cashew nut OIT had a low frequency
of adverse effects and was generally well tolerated. However, patient
characteristics influenced side effect risk and treatment duration,
emphasizing the need for individualized OIT plans.
Automatic monitoring of drug associated muscle adverse reaction in 102430 inpatients
Authors: Zhao Anqi , Guo Daihong , Zhu Man , Gao Ao , Li Peng , Fu An
Published: October 2023

OBJECTIVE: To analyze clinical characteristics, incidence, and
distribution of drug associated muscle adverse reaction (DAMAR) in real
world inpatients, to provide references for clinical medication use.
METHODS: Automated retrospective monitored inpatients from 2022-5-1 to
2023-4-30 to obtain information about patients’ adverse reactions and
analyze. RESULTS: There were 1106 DAMARs among 102430 hospitalizations,
with an incidence of 1.08%, in which 125 cases of rhabdomyolysis with
an incidence of 0.12%. 75% of the patients experienced muscle adverse
reactions within 5 days after medication, and the median value of
elevated CK was 420.4 IU/L. There was no significant correlation between
duration of surgery and the elevation of CK, while the surgical
procedure had an effect. Age, male sex, obesity, hypertension, hepatic
and renal insufficiency, anemia, and other underlying diseases were risk
factors. The 114 drugs involved were mainly nervous system drugs,
antiinfectives for systemic use and cardiovascular system drugs, with
levofloxacin, pregabalin and parecoxib being the drugs with the highest
number of cases. CONCLUSION: Attention should be paid to patients with
the above risk factors. Monitor creatine kinase and related indexes when
using myotoxic drugs, to avoid the occurrence of serious adverse
reactions, which may affect the patients’ quality of life.
Deinococcus wulumuqiensis R12 synthesized silver nanoparticles with peroxidase-like activity for synergistic antibacterial application
Authors: Liu Jingjia , Zhang Nan , Shen Bowen , Zhang Liling , Zhang Zhidong , Zhu Liying , Jiang Ling
Published: October 2023

The use of a combination of several antibacterial agents for therapy
holds great promise in reducing the dosage and side effects of these
agents, improving their efficiency, and inducing potential synergistic
therapeutic effects. Herein, R12-AgNPs were produced with the
supernatant of an ionizing radiation-tolerant bacterium Deinococcus
wulumuqiensis R12 by one-step under room temperature. The biosynthesized
AgNPs presented fascinating antibacterial activity and peroxidase-like
properties, which endowed it with the capability to catalyse the
decomposition of H2O2 to generate hydroxyl radical. After combination of
R12-AgNPs and H2O2, an excellent synergistic bacteriostatic activity was
observed for both E. coli and S. aureus, especially at low
concentrations. In addition, in vitro cytotoxicity tests showed
R12-AgNPs had good biocompatibility. Thus, this work presents a novel
antibacterial agent that exhibits favorable synergistic antibacterial
activity and low toxicity, without the use of antibiotics or a
complicated synthesis process.
The mass scale law of the Universe
Authors: Pellis Stergios
Published: October 2023

In this paper we will present a new mass scale law of the universe. First from the Dimensionless unification of the fundamental interactions we will find the formulas for the Planck mass. It will be presented as an extended mass relation for fundamental masses. Also we will find the expressions for the minimum mass and the mass of the observable universe.
Assessing the Regional Climate Response to Different Hengduan Mountains Geometries with a High-Resolution Regional Climate Model
Authors: Xiang Ruolan , Steger Christian Roland , Li Shuping , Pellissier Loïc , Sørland Silje Lund , Willett Sean , Schär Christoph
Published: October 2023

The Hengduan Mountains (HM) are located on the southeastern edge of the
Tibetan Plateau (TP) and feature high mountain ridges (>
6000 m a.s.l.) separated by deep valleys. The HM region also features an
exceptionally high biodiversity, believed to have emerged from the
topography interacting with the climate. To investigate the role of the
HM topography on regional climate, we conduct simulations with the
regional climate model COSMO at high horizontal resolutions (at
~12 km and a convection-permitting scale of
~4.4 km) for the present-day climate. We conduct one
control simulation with modern topography and two idealised experiments
with modified topography, inspired by past geological processes that
shaped the mountain range. In the first experiment, we reduce the HM’s
elevation by applying a spatially non-uniform scaling to the topography.
The results show that, following the uplift of the HM, the local rainy
season precipitation increases by ~25%. Precipitation
in Indochina and the Bay of Bengal (BoB) also intensifies. Additionally,
the cyclonic circulation in the BoB extends eastward, indicating an
intensification of the East Asian summer monsoon. In the second
experiment, we remove the deep valley by applying an envelope topography
to quantify the effects of terrain undulation with high amplitude and
frequency on climate. On the western flanks of the HM, precipitation
slightly increases, while the remaining fraction of the mountain range
experiences ~20% less precipitation. Simulations
suggest an overall positive feedback between precipitation, erosion, and
valley deepening for this region, which could have influenced the
diversification of local organisms.
Natural variability can mask forced permafrost response to stratospheric aerosol injection in the ARISE-SAI-1.5 simulations
Authors: Morrison Ariel Lena , Barnes Elizabeth A. , Hurrell James Wilson
Published: October 2023

Stratospheric aerosol injection (SAI has been proposed as a potential
method for mitigating risks and impacts associated with anthropogenic
climate change. One such risk is widespread permafrost thaw and
associated carbon release. While permafrost has been shown to stabilize
under different SAI scenarios, natural variability may lead to a wide
range of projected climate futures under SAI. Here we use the 10-member
ensemble from the ARISE-SAI-1.5 simulations to assess the spread in
projected active layer depth and permafrost temperature across boreal
permafrost soils and specifically in four peatland and Yedoma regions.
The forced response in active layer depth and permafrost temperature
quickly diverge between an SAI and non-SAI world, but individual
ensemble members overlap for several years following SAI deployment.
Projected permafrost variability may mask the forced response to SAI and
make it difficult to detect if and when SAI is stabilizing permafrost in
any single realization. We find that it may take more than a decade of
SAI deployment to detect the effects of SAI on permafrost temperature
and almost 30 years to detect its effects on active layer depth. Not
only does natural variability make it more difficult to detect SAI’s
influence, it could also affect the likelihood of reaching a permafrost
tipping point. In some realizations, SAI fails to prevent a tipping
point that is also reached in a non-SAI world. Our results underscore
the importance of accounting for natural variability in assessments of
SAI’s potential influence on the climate system.
The modeled seasonal cycles of land biosphere and ocean N2O fluxes and atmospheric N2O
Authors: Sun Qing , Joos Fortunat , Lienert Sebastian , Berthet Sarah , Carroll Dustin , Gong Cheng , Ito Akihiko , Jain Atul , Kou-Giesbrecht Sian , Landolfi Angela , Manizza Manfredi , Pan Naiqing , Prather Michael J. , Regnier Pierre , Resplandy Laure , Séférian Roland , Shi Hao , Suntharalingam Parvadha , Thompson Rona L. , Tian Hanqin , Vuichard Nicolas , Zaehle Sönke , Zhu Qing
Published: October 2023

Nitrous oxide (N2O) is a greenhouse gas and an ozone-depleting agent
with large and growing anthropogenic emissions. Previous studies
identified the influx of N2O-depleted air from the stratosphere to
partly cause the seasonality in tropospheric N2O (aN2O), but other
contributions remain unclear. Here we combine surface fluxes from eight
land and four ocean models from phase 2 of the Nitrogen/N2O Model
Intercomparison Project with tropospheric transport modeling to simulate
aN2O at the air sampling sites: Alert, Barrow, Ragged Point, Samoa,
Ascension Island, and Cape Grim for the modern and preindustrial
periods. Models show general agreement on the seasonal phasing of
zonal-average N2O fluxes for most sites, but, seasonal peak-to-peak
amplitudes differ severalfold across models. After transport, the
seasonal amplitude of surface aN2O ranges from 0.25 to 0.80 ppb
(interquartile ranges 21-52% of median) for land, 0.14 to 0.25 ppb
(19-42%) for ocean, and 0.13 to 0.76 ppb (26-52%) for combined flux
contributions. The observed range is 0.53 to 1.08 ppb. The stratospheric
contributions to aN2O, inferred by the difference between
surface-troposphere model and observations, show 36-126% larger
amplitudes and minima delayed by ~1 month compared to
Northern Hemisphere site observations. Our results demonstrate an
increasing importance of land fluxes for aN2O seasonality, with land
fluxes and their seasonal amplitude increasing since the preindustrial
era and are projected to grow under anthropogenic activities. In situ
aN2O observations and atmospheric transport-chemistry models will
provide opportunities for constraining terrestrial and oceanic biosphere
models, critical for projecting surface N2O sources under ongoing global
warming.
Looking beyond the surface: Muir Torre syndrome
Authors:   Department of Medicine, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand, Bagga Ekta , Innes David ,   Taranaki Pathology Services, New Plymouth, Taranaki, New Zealand, Leung Edmund ,   Department of Medicine, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand
Published: October 2023

Muir-Torre Syndrome (MTS) is associated with multiple visceral malignancies. Initial presentation may be a benign skin tumor mimicking a sebaceous cyst. This case report highlights the importance of early diagnosis, genetic testing, and multidisciplinary screening. A 67-year-old man was diagnosed with MTS following excision of a skin lesion (sebaceoma). He was declined both screening colonoscopy and genetic testing. Subsequently, advanced colon cancer was found following presentation with iron deficiency anemia, which ultimately led to palliation despite successful surgery. MTS can present insidiously with skin lesions clinically diagnosed as sebaceous cysts. Once MTS is suspected on histology, genetic testing and screening for MTS-related cancers is warranted. Better understanding of the genetic variants for MTS can aid in earlier diagnosis thus not dismissing the need for screening for MTS-related cancers.
Polycystic ovary syndrome due to the novel translocation 46XX t(2;9)(q21;p24)
Authors:   Neurology Department, Neurology & Neurophysiology Center, Vienna, Austria, Finsterer Josef
Published: October 2023

The etiology of polycystic ovary syndrome (PCOS) is not exactly known, but there are indications that genetic factors, exposure to androgen in early childhood, and obesity lead to a disruption of the hypothalamic-pituitary-ovarian axis and dysregulation of microRNAs. Chromosomal aberrations have rarely been described as a cause of PCOS. We present the case of a 20-year-old female diagnosed with PCOS at age 17 due to hyperandrogenism, obesity, polycystic ovaries, amenorrhoea, and emerging insulin resistance. A work-up for the cause of PCOS revealed a previously undescribed translocation 46XX t(2;9)(q21;p24). Alternative causes of PCOS were excluded. In addition, the patient had post-COVID syndrome. The patient was treated with contraceptive pills. PCOS can be caused by the translocation 46XX t(2;9)(q21;p24). The clinical manifestations of PCOS can be exacerbated by post-COVID syndrome.
Valproate-induced burning mouth syndrome in a male with fibromyalgia and bipolar spectrum disorder
Authors:   Department of Psychiatry, Unit of Psychiatric Disorders in Medical Complex Pathologies, University of Pisa, Pisa, Italy, Raia Accursio , Caruso Valerio ,   Department of Psychiatry, Unit of Psychiatric Disorders in Medical Complex Pathologies, University of Pisa, Pisa, Italy, Montalbano Clara ,   Department of Psychiatry, Unit of Psychiatric Disorders in Medical Complex Pathologies, University of Pisa, Pisa, Italy
Published: October 2023

Burning mouth syndrome is a chronic painful condition characterized by a subjective intraoral pain and burning sensations in the absence of an identifiable medical, dental, or psychiatric cause. Although the underlying etiology is currently unclear, an idiopathic (or primary) form and a secondary form to other conditions are formally recognized. However, as several authors have suggested, it might be of clinical utility to consider the existence of a third clinical entity, namely Drug-Induced Burning mouth syndrome, for its therapeutic implications. The latter has been reported with angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, antiretrovirals, anticoagulants, chemotherapy, and drugs commonly used in the treatment of neuropsychiatric disorders such as antidepressants, benzodiazepines, and antipsychotics. Regarding anticonvulsants a literature search found a previous case of Topiramate-Induced Burning mouth syndrome but no previous report of valproate-induced Burning mouth syndrome. Our case is, to date, the first case in the literature of Burning mouth syndrome onset following the administration of valproate to a patient suffering from fibromyalgia and bipolar spectrum disorder. Symptoms resolved completely when the drug was stopped, and the association between symptoms and drug was replicated after drug re-administration.
Solitary superficial angiomyxoma of the ear pinna: a diagnostic dilemma with a review of literature
Authors:   Department of Pathology, King George Medical University, Lucknow, India, Singh Anurag , Rawat Shalini ,   Department of Pathology, King George Medical University, Lucknow, India, Kumar Gulshan ,   Department of Pathology, King George Medical University, Lucknow, India
Published: October 2023

Superficial angiomyxoma is an extremely rare subcutaneously placed myxoid soft tissue neoplasm. There are few case reports with fine needle aspiration cytological and histopathological findings available for this tumor because of its rarity. Here, we describe a case of superficial angiomyxoma in a 24-year-old girl who had a solitary left ear pinna mass without a Carney's complex at the time of presentation or at the end of two years of follow-up next to the surgical removal of the tumor. The clinical, cytomorphological, and histological findings, together with the immunohistochemical markers, in a case of superficial angiomyxoma are described in this rare case report for the first time in the English literature.
Xanthogranulomatous epithelial tumor: a novel entity of uncertain biologic potential
Authors:   Division of Pathology, Cantonal Hospital Lucerne, Switzerland, Svantesson Teodor , van Oudenaarde Kim ,   Division of Radiology, Cantonal Hospital Lucerne, Switzerland, Fuchs Bruno ,   Division of Orthopedics, Cantonal Hospital Lucerne, Switzerland
Published: October 2023

Xanthogranulomatous epithelial tumor (XGET) is an extremely rare and recently described mesenchymal neoplasm characterized by a distinctive histological appearance and clinical presentation. This case report describes a unique case of XGET in a 66-year-old female patient who presented with a 5 cm mass in the dorsal distal left thigh. The clinical, radiological, and pathological findings, as well as the management and follow-up, are discussed.
Clinical significance of the living kidney donor profile index for predicting long-term posttransplant outcomes: results from the Korean Organ Transplantation Registry
Authors: Kim Jong Ho , Lee Sang Ho , Kim Jin Sug , Hwang Hyeon Seok , Ko Hyunmin , Jung Cheol-Woong , Kim Deok Gie , Kim Yeong Hoon , Yang Jaeseok , Ahn Curie , Jeong Kyung Hwan ,   the Korean Organ Transplantation Registry Study Group
Published: October 2023

Background: The usefulness of the living kidney donor profile index (LKDPI) has not been widely demonstrated; therefore, it requires verification before clinical application. We analyzed the LKDPI using data from the Korean Organ Transplantation Registry (KOTRY) to confirm whether the LKDPI can be used to predict the survival of allografts in living donor kidney transplantation (LDKT) patients in Korea. Methods: The study population was obtained from the KOTRY database. A total of 2,598 kidney recipients registered in the KOTRY database were enrolled between May 2014 and December 2020. Donor and recipient information was observed, and the LKDPI was measured. Results: Median LKDPI score was 15.5 with a follow-up duration of 33.7 ± 16.1 months. According to LKDPI scores (group 1, <0; group 2, 0–20; group 3, 20–40; and group 4, >40), LKDPI group 4 had significantly higher death-censored graft loss than LKDPI group 1 (hazard ratio [HR], 1.89; 95% confidence interval [CI], 1.06– 3.40; p = 0.03). When divided based on the cutoff value (LKDPI, 36.6), the high LKDPI group had higher graft loss than the low LKDPI group (HR, 2.14; 95% CI, 1.37–3.34; p < 0.001). When follow-up was repeated after transplantation, it was confirmed that the higher the LKDPI value was, the lower the average estimated glomerular filtration rate (p < 0.001). Conclusion: This study confirmed that LKDPI can serve as an independent predictor for assessing the risk of allograft failure and transplant outcomes in Korean LDKT patients.
Machine learning-based 2-year risk prediction tool in immunoglobulin A nephropathy
Authors: Kim Yujeong , Jhee Jong Hyun , Park Chan Min , Oh Donghwan , Lim Beom Jin , Choi Hoon Young , Yoon Dukyong , Park Hyeong Cheon
Published: October 2023

Background: This study aimed to develop a machine learning-based 2-year risk prediction model for early identification of patients with rapid progressive immunoglobulin A nephropathy (IgAN). We also assessed the model’s performance to predict the long-term kidney-related outcome of patients. Methods: A retrospective cohort of 1,301 patients with biopsy-proven IgAN from two tertiary hospitals was used to derive and externally validate a random forest-based prediction model predicting primary outcome (30% decline in estimated glomerular filtration rate from baseline or end-stage kidney disease requiring renal replacement therapy) and secondary outcome (improvement of proteinuria) within 2 years after kidney biopsy. Results: For the 2-year prediction of primary outcomes, precision, recall, area-under-the-curve, precision-recall-curve, F1, and Brier score were 0.259, 0.875, 0.771, 0.242, 0.400, and 0.309, respectively. The values for the secondary outcome were 0.904, 0.971, 0.694, 0.903, 0.955, and 0.113, respectively. From Shapley Additive exPlanations analysis, the most informative feature identifying both outcomes was baseline proteinuria. When Kaplan-Meier analysis for 10-year kidney outcome risk was performed with three groups by predicting probabilities derived from the 2-year primary outcome prediction model (low, moderate, and high), high (hazard ratio [HR], 13.00; 95% confidence interval [CI], 9.52–17.77) and moderate (HR, 12.90; 95% CI, 9.92–16.76) groups showed higher risks compared with the low group. From the 2-year secondary outcome prediction model, low (HR, 1.66; 95% CI, 1.42–1.95) and moderate (HR, 1.42; 95% CI, 0.99–2.03) groups were at greater risk for 10-year prognosis than the high group. Conclusion: Our machine learning-based 2-year risk prediction models for the progression of IgAN showed reliable performance and effectively predicted long-term kidney outcome.
Pengembangan Wayang Digital Untuk Menguatkan Karakter Cinta Budaya Daerah Pada Anak Usia Dini
Authors: Fahad Ainun Najib  , Nurbiana Dhieni  , Nurjannah
Published: October 2023

Budaya daerah memiliki kekayaan yang perlu diperhatikan dan ditangani secara cermat, terutama dalam memasuki perkembangan era globalisasi. Pentingnya keberadaan budaya daerah, karena unsur-unsur budaya dalam kenyataannya memberi andil yang sangat besar bagi pembentukan jati diri bangsa. Budaya yang sangat beragam di Indonesia dapat dijadikan media sebagai penyampaian pendidikan karakter kepada anak.

Globalisasi selain berpengaruh terhadap eksistensi budaya pertukaran informasi antar negara yang tidak terkontrol menyebabkan tergerusnya rasa cinta akan budaya sendiri, salah satunya yaitu kesenian wayang. Hal ini merupakan acaman dalam masa depan, oleh sebab itu harus ditanamkan karakter cinta budaya daerah kepada anak agar dapat mempertahankan dan mengenali budaya bangsa sendiri. Globalisasi harus dimanfaatkan kedalam budaya di Indonesia, dengan adanya globalisasi seharusnya kebudayaan di Indonesia lebih mudah diketahui dan diperkenalkan kepada generasi penerus, contohnya menggunakan kanal video online Youtube/Youtube Kids. Pengembangan digitalisasi akan menggunakan model ADDIE (1) Analize,(2) Design,(3) Development,(4) Implementation,(5) Evaluation.
The effect of corticosteroid use in septic shock on secondary infection frequency, microorganism species, morbidity, and mortality
Authors: Calili Duygu Kayar , Izdes Seval , Ozturk Levent
Published: October 2023

Aim: We aimed to examine the effect of corticosteroid treatment in vasopressor-refractory septic shock on secondary infections, microorganism species, survival, and length of hospital stay.

Material and methods: In this observational study, the records of 108 septic shock patients admitted to the intensive care unit (ICU) were reviewed. Patients were divided into two groups: the corticosteroid group (Group S, n=60) and the non-corticosteroid group (Group S-0, n=48). The results of three cultures [blood, endotracheal aspirate (eta), urine, wound] taken after ICU admission were recorded. The groups were compared in terms of demographic characteristics, culture growth rates and microorganisms, length of hospital stay, and survival rates.

Results: The hospital (p=0.043) and ICU stay (p=0.035) were longer in Group S. There was no significant difference between the groups in terms of survival (p>0.05). The growth rate of the first urine culture was significantly higher in Group S-0 than in Group S (p=0.018), but there was no difference in terms of microorganism species (p>0.05). There was no significant difference in growth rates and microorganism species in blood, eta and wound cultures (p>0.05), but increase in growth rates were observed in the 2nd and 3rd eta and, wound cultures compared to first culture in Group S (p<0.05).

Conclusion: There was no difference between the patients who received and did not receive corticosteroid treatment in septic shock in terms of culture growth rates, growing microorganism species and mortality; however, the frequency of growth in eta and wound cultures increased and the length of hospital stay was longer in patients who received corticosteroids.
Unraveling the interplay: Exploring the relationship between children's obesity, sleep disorders, depressive symptoms, and age dynamics
Authors: Orhan Kiliç Betül , Çakmak Eda
Published: October 2023

Objective: This study explores the relationships between sleep disorders, depressive symptoms, and obesity among children of different ages.

Material and methods: The data for this study were collected from 163 Turkish children aged 7 to 10 and 11 to 15 years (mean age=9.4, SD=1.9) who were attending well-child visits. Parents completed an online questionnaire on sociodemographic data, while children completed the Children Depression Inventory and The Children's Sleep Habits Questionnaire.

Results: The regression model for the 7-10 years group included sleep resistance, sleep onset delay, nighttime awakenings, and daytime sleepiness, and explained 33.8% of the variance in Children Depression Inventory scores (R2=0.338, F=9.779, p<0.001). For the 11-15 age group, the regression model included obesity status, Children's Sleep Habits Questionnaire scores, sleep onset delay, sleep-related anxiety, and sleep-disordered breathing, and explained 80.3% of the variance in Children Depression Inventory scores (R2=0.803, F=28.489, p<0.001).

Conclusion: Overall, the results of this study emphasize the significance of addressing sleep disorders, obesity, and depressive symptoms in children, particularly in adolescents, to promote better mental health outcomes.
Intracardiac foreign bodies: Diagnosis and management
Authors: Memmedov Valeh , Emrah Anar , Shahaliyev Ziya , Ibrahimov Javid
Published: October 2023

Introduction: As a result of gunshot wounds due to a bullet or shrapnel entering the system of arteries or veins, direct wounds of the heart or vascular structures, as well as embolisms may occur. After entering one of the systemic veins, the bullet or shrapnel can enter the right heart or the pulmonary artery. Shrapnel embolism is a rare condition, usually asymptomatic and is detected accidentally during routine examinations. Due to the fact that the intensity of occurrence of this type of cases is quite rare, it was decided to present such clinical cases.

Material and methods: This article reports about 3 patients with intracardiac foreign body. All 3 patients took part in the battles during the Second Karabakh War and were hospitalized as a result of shrapnel wounds received in different parts of the body. In each of the patients, the lesion area was different, but as a result of venous migration, the movement of a foreign body (metal fragment) in the heart cavity was noted. In two patients, the foreign body was removed by open surgery (connection to a heart-lung machine) due to the presence of symptoms, but one patient was under observation due to the absence of symptoms.

Results: Bullet or shrapnel embolism is a very rare complication of gunshot wounds, occurring in about 0.3% of cases. These emboli often cause antegrade migration into the arterial system. However, in about 20% of cases, migration into the venous system can also occur. Venous embolism often results in foreign body migration into the right heart or the pulmonary artery. The diagnosis in these cases is often established by chance, but in some cases, arrhythmias and valve defects can occur due to exposure to a foreign body. The identification of such cases depends on the symptoms. A foreign body can be removed by an open method, as well as by invasive methods. In some cases, it is possible to keep the foreign body under control when it does not cause any symptoms.

In the clinical cases we mentioned, we also mentioned the management of cases of foreign bodies entering the venous system from peripheral zones of penetration.
ANALYSIS OF URBAN TRANSFORMATIONS AND THEIR IMPACT ONTHE COLONIAL URBAN FABRIC IN DJELFA (ALGERIA) USING SPACE SYNTAX TECHNIQUE
Authors:   Ziane Achour University, Ahmed Brahim , Boudjemaa Khalfallah ,   Mohamed Boudiaf University
Published: October 2023

Introduction: The paper examines the urban transformations that Djelfa underwent over time, from its colonial inception to the present day, characterized by rapid demographic and urban growth as well as excessive consumption of urban space. Purpose of the study: We aimed to study the urban transformations of the city of Djelfa over time, provide a quantitative description of the urban and social characteristics that shape the built environment, and identify the city’s most integrated (easily accessible) and secluded areas. Methods: We utilized the spatial syntax technique to analyze the stages of city development, which is based on modeling city maps into axial maps and quantitatively measuring various factors such as connectivity and integration (Rn). Results: We obtained significant results notably that the historical city center still maintains its importance in terms of easy access, interconnected axes, and chess layout that facilitated its expansion. Additionally, residential neighborhoods, isolated from the rest of the city, emerged at certain periods. Restructuring operations, such as the opening of Mohamed Boudiaf Square in the city center, contributed to increasing connectivity with its neighboring axes.
Los presupuestos y la toma de decisiones
Authors: Luperdi Castañeda José Américo , Alzamora Carrión José Henry , Velasco Taipe Marco Antonio
Published: October 2023

El libro está preparado en función, desde el inicio, de analizar o identificar cada una de las técnicas presupuestales; después de la identificación nos va a permitir realizar la respectiva programación o cuantificación de las unidades sea la real, la apropiada dándonos la seguridad de que dicha determinación es la correcta; permitiendo de esta manera que los valores que vamos a considerar en los presupuestos sean una base fuente y segura de lograr alcanzar la meta propuesta; y hasta usar estos datos presupuestados en la toma de decisiones con la finalidad de tomar la decisión correcta a través de dicha evaluación denominada Control Presupuestario.
Meaning and philosophy of Bale beleq traditional house East Lombok
Authors: Septiana Elmi , Afandi Ahmad , Ilmiawan Ilmiawan , Herianto Agus
Published: October 2023

The Bale beleq traditional house of Jerowaru Village and Wakan Village is a historical heritage. This house is different from ordinary traditional houses because Bale beleq is occupied by people who are respected. In addition, there are also historical relics such as keris, swords, and many more. This research aims to examine information about the meaning and philosophy of the Bale beleq traditional house. This research was conducted in Jerowaru Village and Wakan Village. Eight respondents were interviewed. The research method used was the qualitative method. Data collection was done by using observation, interview, and documentation methods. The data analysis techniques are data collection, data reduction, data presentation, and conclusion drawing or verification. The results of the study found the history of the emergence of the Bale beleq traditional house, the meaning and philosophy of Bale beleq, and the values within Bale beleq. Currently, Bale beleq is used as a center for socio-cultural religious activities. One way to maintain and preserve traditional houses is to make the house a cultural heritage so that it does not erode with the time, and to make Bale beleq an educational and cultural tour site.
Experience in conducting tax amnesty in developing countries before the introduction of automatic exchange of tax information
Authors: Muzyka-Stefanchuk O. , Masyakin I.
Published: October 2023

The author provides a detailed overview of an article that examines tax amnesty programs within the framework of international tax initiatives like the BEPS Action Plan and the Common Reporting Standard (CRS). The article argues that the integration of these global initiatives and domestic tax amnesties has complex and far-reaching implications for taxpayer behavior, government revenue, and fiscal policy at large. The key themes of the article focus on global tax initiatives, the effectiveness of tax amnesties, the criteria for a successful amnesty program, and their ethical and social implications. The article underscores the transformative role of global frameworks like CRS and BEPS in tax enforcement, pointing to unprecedented levels of transparency and international cooperation. While the short-term revenue boosts from tax amnesties are acknowledged, the article argues that the long-term impacts of these programs on tax compliance and fiscal integrity are less certain. This makes the article’s detailed set of conditions for an effective tax amnesty program particularly valuable for policymakers. The ethical and social implications of tax amnesties are also explored, emphasizing that public trust is crucial for the success of these programs.

In terms of methodology, the article combines qualitative analysis with empirical data, such as the OECD survey conducted in 2015, to build its arguments. Its comprehensive approach integrates perspectives from economics, law, and political science, making the findings relevant for a broad audience.

In conclusion, the article is a significant contribution to the growing body of literature on tax policy and international cooperation. It offers a nuanced understanding of how domestic tax amnesties interact synergistically with global tax initiatives to impact compliance and revenue collection.
Sexual violence against a child: latency and ways to overcome
Authors: Vasylevich V. , Levchenko Yu.
Published: October 2023

The article analyzes the problems of sexual violence and violence against children in general, the detection of sexual violence against a child, the problems of the latency of these crimes, the causes and consequences of this phenomenon in society, possible ways to overcome this problem, and therefore reduce the number of violent crimes against children. The legislation of Ukraine provides for responsibility for committing any violent acts of a sexual nature against children: rape (Article 152 of the Criminal Code of Ukraine), sexual violence (Article 153 of the Criminal Code of Ukraine), coercion into sexual intercourse (Article 154 of the Criminal Code of Ukraine) , sexual intercourse with a person who has not reached the age of sixteen (Article 155 of the Criminal Code of Ukraine), corruption of minors (Article 156 of the Criminal Code of Ukraine), molestation of a child for sexual purposes (Article 156-1 of the Criminal Code of Ukraine), importation, production, sale and distribution of pornographic objects (Article 301 of the Criminal Code of Ukraine), obtaining access to child pornography, its purchase , storage, importation, transportation or other movement, manufacture, sale and distribution (art. 301-1), conducting a spectacular event of a sexual nature with the participation of a minor (art. 301-2), creating or maintaining places of debauchery and prostitution (art. 302 of the Criminal Code of Ukraine), pimping or involving a person in prostitution (Article 303 of the Criminal Code of Ukraine). According to the available data of the Ministry of Internal Affairs of Ukraine, the dynamics of committing violent crimes of a sexual nature is increasing from year to year. In order to effectively detect, investigate and counter these crimes, the state and individuals must rely on a theoretical foundation, which in turn must be developed by specialists-practitioners, police officers, psychologists, teachers, etc., which are understood to be on a legal basis, as well as on the psychological characteristics of children.

The fight against violent crimes of a sexual nature against children and the latency of these crimes will be effective under the condition of interaction and close cooperation of the state, society and the family.