bluuebunny/crossref_metadata_2025 huggingface dataset:
Virus-Specific T-Cell Therapy for Viral Infections of the Central Nervous System: A Review
Authors: Lambert Nicolas , El Moussaoui Majdouline , Baron Frédéric , Maquet Pierre , Darcis Gilles
Published: July 2023

Opportunistic viral infections of the central nervous system represent a significant cause of morbidity and mortality among an increasing number of immunocompromised patients. Since antiviral treatments are usually poorly effective, the prognosis generally relies on the ability to achieve timely immune reconstitution. Hence, strategies aimed at reinvigorating antiviral immune activity have recently emerged. Among these, virus-specific T-cells are increasingly perceived as a principled and valuable tool to treat opportunistic viral infections. Here we briefly discuss how to develop and select virus-specific T-cells, then review their main indications in central nervous system infections, including progressive multifocal leukoencephalopathy, CMV infection, and adenovirus infection. We also discuss their potential interest in the treatment of progressive multiple sclerosis, or EBV-associated central nervous system inflammatory disease. We finish with the key future milestones of this promising treatment strategy.
Impact of Alteplase on Mortality in Critically Ill Patients with COVID-19 and Pulmonary Embolism
Authors: Oliynyk Oleksandr Valentynovych , Rorat Marta , Solyarik Serhij Oleksandrovych , Lukianchuk Vitaliy Andrijovych , Dubrov Serhij Oleksandrovych , Guryanov Vitaliy Hrygorovych , Oliynyk Yanina Volodymyrivna , Yaroslavskaya Svitlana Mykolaivna , Szalast Roman , Barg Wojciech
Published: July 2023

COVID-19 is an independent risk factor for pulmonary embolism (PE). Little is known about alteplase therapy in this patient group. A retrospective study analyzed 74 patients with PE and acute respiratory distress syndrome (ARDS) due to COVID-19 who were hospitalized in the intensive care unit in 2021. Patients with or without confirmed right heart thrombi (RHT) were treated with unfractionated heparin or alteplase. The mortality rate in patients with RHT treated with heparin was 100% compared to 37.9% and 55.2% in those treated with alteplase without RHT and alteplase with RHT, respectively. The risk of death in the alteplase group increased with delayed thrombolysis (p = 0.009, odds ratio (OR) = 1.73 95% CI (confidence interval) 1.14–2.62), increased D-dimer concentration (p = 0.02, OR = 1.43 95% CI 1.06–1.93), and decreased PaO2/FiO2 ratio (p = 0.001, OR = 0.56 95% CI 0.41–0.78). The receiver operating characteristic method determined that a 1-day delay in thrombolytic treatment, D-dimer concentration >5.844 mg/L, and PaO2/FiO2 <144 mmHg predicted a fatal outcome. The risk of death in patients with severe COVID-19 with ARDS and PE increases with higher D-dimer levels, decreased PaO2/FiO2, and delayed thrombolytic treatment. Thrombolysis seems to be treatment of choice in severe COVID-19 with PE and RHT. It should be carried out as soon as possible after the diagnosis is established.
Adjuvanted Fusion Protein Vaccine Induces Durable Immunity to Onchocerca volvulus in Mice and Non-Human Primates
Authors: Ryan Nathan M. , Hess Jessica A. , Robertson Erica J. , Tricoche Nancy , Turner Cheri , Davis Jenn , Petrovsky Nikolai , Ferguson Melissa , Rinaldi William J. , Wong Valerie M. , Shimada Ayako , Zhan Bin , Bottazzi Maria Elena , Makepeace Benjamin L. , Gray Sean A. , Carter Darrick , Lustigman Sara , Abraham David
Published: July 2023

Onchocerciasis remains a debilitating neglected tropical disease. Due to the many challenges of current control methods, an effective vaccine against the causative agent Onchocerca volvulus is urgently needed. Mice and cynomolgus macaque non-human primates (NHPs) were immunized with a vaccine consisting of a fusion of two O. volvulus protein antigens, Ov-103 and Ov-RAL-2 (Ov-FUS-1), and three different adjuvants: Advax-CpG, alum, and AlT4. All vaccine formulations induced high antigen-specific IgG titers in both mice and NHPs. Challenging mice with O. volvulus L3 contained within subcutaneous diffusion chambers demonstrated that Ov-FUS-1/Advax-CpG-immunized animals developed protective immunity, durable for at least 11 weeks. Passive transfer of sera, collected at several time points, from both mice and NHPs immunized with Ov-FUS-1/Advax-CpG transferred protection to naïve mice. These results demonstrate that Ov-FUS-1 with the adjuvant Advax-CpG induces durable protective immunity against O. volvulus in mice and NHPs that is mediated by vaccine-induced humoral factors.
Associations between COVID-19 Vaccination and Behavioural Intention to Receive Seasonal Influenza Vaccination among Chinese Older Adults: A Population-Based Random Telephone Survey
Authors: Liang Xue , Li Jiming , Fang Yuan , Zhang Qingpeng , Wong Martin C. S. , Yu Fuk-yuen , Ye Danhua , Chan Paul Shing-fong , Kawuki Joseph , Chen Siyu , Mo Phoenix K. H. , Wang Zixin
Published: July 2023

During the Coronavirus Disease 2019 (COVID-19) pandemic, seasonal influenza remained a significant health threat for older adults. Seasonal influenza vaccination (SIV) is highly effective and safe for older adults. This study investigated the associations of COVID-19 vaccination, perceptions related to COVID-19 and SIV, with the behavioural intention to receive SIV among older adults in Hong Kong, China. A random telephone survey was conducted among 440 community-dwelling Hong Kong residents aged 65 years or above, between November 2021 and January 2022. Among the participants, 55.7% intended to receive SIV in the next year. After adjustment for significant background characteristics, concern about whether SIV and COVID-19 vaccination would negatively affect each other was associated with a lower intention to receive SIV, while a perceived higher risk of co-infection with COVID-19 and seasonal influenza was positively associated with the dependent variable. In addition, the perceived severe consequences of seasonal influenza, perceived benefits of SIV, received cues to action from doctors and participants’ family members or friends, and the perception that more older people would receive SIV was associated with a higher behavioural intention. Future programmes promoting SIV among older adults should modify perceptions related to COVID-19 vaccination and SIV at the same time.
Synthesis of Ag-OMS Catalyst for Sunlight-Assisted Photodegradation of Crystal Violet Dye
Authors: Saeed Muhammad , Pecho Renzon Daniel Cosme , Panchal Sandeep , Alhag Sadeq K. , Al-Shuraym Laila A. , Al Syaad Khalid M. , Bhutta Usman Hanif
Published: July 2023

The contamination of water with organic pollutants, such as dyes, has become a serious threat to the environment. Therefore, the development of a cost-effective, eco-friendly, proficient, and visible-light-driven catalyst for the treatment of organic dye-contaminated wastewater has been a burning issue recently. Photocatalysis is suggested as a potential treatment technique for the eradication of organic pollutants. The 1D tunnel-structured manganese oxide octahedral molecular sieve (OMS) is a suitable substance to be tested as a visible-light-driven photocatalyst for the degradation of organic contaminants. However, the fast recombination of photoinduced charges (h+/e−) limits its photocatalytic application. The development of heterojunctions between OMS and other metals, such as Ag, is a suitable technique for improving the photocatalytic performance of OMS. In this study, Ag-OMS with plasmon-enhanced photocatalytic activity is reported for the photodegradation of crystal violet dye. Manganese oxide OMS was prepared by an acidic precipitation method using potassium permanganate, manganese acetate, and nitric acid as precursor materials. Ag nanoparticles were deposited on OMS using leaf extracts of Calotropis gigantea. The deposition of Ag enhanced the photocatalytic performance of OMS from 68 to 95%. The effects of Ag contents, catalyst dosage, and concentration of crystal violet dye on catalytic performance were explored as well. Approximately 100, 95, and 75% photodegradation of 50, 100, and 150 mg/L crystal violet dye was observed in 90, 120, and 120 min in the presence of 10% Ag-OMS, respectively. Excellent photocatalytic performance, low dose utilization, and reusability proved that Ag-OMS might have practical environmental applications.
The Vital Roles of Parent Material in Driving Soil Substrates and Heavy Metals Availability in Arid Alkaline Regions: A Case Study from Egypt
Authors: Alnaimy Manal , Elrys Ahmed , Zelenakova Martina , Pietrucha-Urbanik Katarzyna , Merwad Abdel-Rahman
Published: July 2023

Despite studies focusing on soil substrates (carbon and nitrogen) and heavy metal availability, the impact of diversified parent materials in arid alkaline regions has received little attention. To reveal the influence of parent material, we investigated four different parent materials: fluvio-marine, Nile alluvial, lacustrine, and aeolian deposits. We assessed the effect of soil parent materials through selected soil physical and chemical properties, such as clay content, bulk density, pH, and available phosphorus (AP). The Tukey HSD test (SPSS ver. 23) was used to assess the soils derived from these different sediments. Using the R “glmulti” package, we examined this effect in a model of mixed-effects meta-regression. The sum of Akaike weights for models that contained each element was used to estimate the importance of each factor. The average contents of soil organic carbon (SOC) and total N in alluvial deposits were greater (p < 0.001) than those of marine, aeolian, and lacustrine deposits. A multivariate analysis in arid regions revealed that parent material, soil pH, and the availability of P had the greatest effects on SOC concentration, whereas clay content, available P, soil pH, parent material, and bulk density had the greatest effects on soil total nitrogen. The average content of Fe in the aeolian deposits was greater (p < 0.001) than those of marine, alluvial, and lacustrine deposits, without any significant differences between the latter two deposits. We found that the highest average contents of zinc (Zn), manganese (Mn), and copper (Cu) were recorded in alluvial deposits, with significant differences between other deposits. Soil parent material was the major factor impacting soil iron (Fe) content, along with clay content and soil pH. However, soil bulk density was the most important factor controlling soil Zn and Mn contents, while SOC drove Cu content. This study will help in developing a more accurate model of the dynamics of soil substrates and availability of heavy metals by considering readily available variables, such as parent materials, soil pH, soil bulk density, and clay content.
Spatiotemporal Characterization of Drought Magnitude, Severity, and Return Period at Various Time Scales in the Hyderabad Karnataka Region of India
Authors: Patil Rahul , Polisgowdar Basavaraj Shivanagouda , Rathod Santosha , Bandumula Nirmala , Mustac Ivan , Srinivasa Reddy Gejjela Venkataravanappa , Wali Vijaya , Satishkumar Umapathy , Rao Satyanarayana , Kumar Anil , Ondrasek Gabrijel
Published: July 2023

Global climate change is anticipated to have a profound impact on drought occurrences, leading to detrimental consequences for the environment, socioeconomic relations, and ecosystem services. In order to evaluate the extent of drought impact, a comprehensive study was conducted in the Hyderabad–Karnataka region, India. Precipitation data from 31 stations spanning a 50-year period (1967–2017) were analyzed using the standardized precipitation index (SPI) based on gamma distribution. The findings reveal that approximately 15% of the assessed years of experienced drought conditions, with a range of influence between 41% and 76% under SPI_3, and between 43% and 72% under SPI_6. Examining the timescale magnitude frequency provided insights into variations in the severity of drought events across different locations and timescales. Notably, the Ballari (−8.77), Chitapur (−8.22), and Aland (−7.40) regions exhibited the most significant magnitudes of drought events for SPI_3 with a 5-year return period. The heightened risk of recurrent droughts in the study area emphasizes the necessity of integrating SPI in decision-making processes, as such integration can markedly contribute to the development of reliable and sustainable long-term water management strategies at regional and national levels.
Frequency Analysis of Hydrological Data for Urban Floods—Review of Traditional Methods and Recent Developments, Especially an Introduction of Japanese Proper Methods
Authors: Mizuki Chiharu , Kuzuha Yasuhisa
Published: July 2023

Frequency analysis has long been an important theme of hydrology research. Although meteorological techniques (physical approaches) such as radar nowcasting, remote sensing, and forecasting heavy rainfall events using meteorological simulation models are quite effective for urban disaster prevention, statistical and stochastic theories that include frequency analysis, which are usually used in flood control plans, are also valuable for flood control plans for disaster prevention. Master plans for flood control projects in urban areas often use the concept of T-year hydrological values with a T-year return period. A flood control target is a “landside area that is safe against heavy rainfall or floods with a return period of T years”. This review emphasizes discussions of parameter estimation of stochastic models and selection of optimal statistical models, which include evaluation of goodness-of-fit techniques of statistical models. Based on those results, the authors criticize Japanese standard procedures recommended by the central government. Consistency between parameter estimation and evaluation of goodness-of-fit is necessary. From this perspective, we recommend using the maximum likelihood method and AIC, both of which are related to Kullback–Leibler divergence. If one prefers using SLSC, we recommend not SLSC itself but SLSC’s non-exceedance probability. One important purpose of this review is the introduction of well-used Japanese methods. Because some techniques that are slightly different from the international standard have been used for many years in Japan, we introduce those in the review article.
Channel Gradient as a Factor in the Distribution of Beaver Dams and Ponds on Small Rivers: A Case Study in the Northern Extremity of the Volga Upland, the East European Plain
Authors: Sharifullin Aidar G. , Gusarov Artyom V. , Lavrova Olga A. , Beylich Achim A.
Published: July 2023

A very noticeable increase in the beaver population (mainly the Eurasian beaver (Castor fiber L.)) in the East European Plain since the end of the 20th century through reintroduction contributed to the emergence of a large number of beaver dams and ponds, which resulted in the transformation of the channels and the hydrological regime of small rivers. In this paper, for the first time in the Middle Volga region, regularities in the distribution of beaver dams and ponds on small rivers were revealed based on a topographic survey of the river channel, regulated by beaver activity in recent decades. The materials of the paper were obtained during field (geodetic) work in August and September of 2022 in the valleys of two small rivers typical for the north of the Volga Upland, Morkváshinka River (16.6 km) and Morkváshka River (7.8 km), with subsequent statistical processing. According to the results obtained, all the dams we encountered were located in the sections of their channels with relatively small (up to 1%) and medium (1–3%) average gradients. In the upper reaches of the rivers, the expansion of beaver activity is limited to the large gradients of their channels. Along the entire length, there is an alternation of sectors with a “natural” (not regulated by beavers) channel and a cascade of beaver ponds. Drained (at the time of the survey) sectors without dams, as well as those with preserved and destroyed dams, were also identified on the Morkváshinka River. On the whole, 26–48% of the length of the studied rivers has been transformed by beaver activity. The average number of dams per kilometer of the watercourse is 3.7–5.1. The most favorable channel gradients for beaver activity are 3.6–16.6 m/km, or 0.36–1.66%. The average gradient of the channel, above which no beaver dams and related ponds were found in these rivers, is 30 m/km, or 3%. An increase in the channel gradient upstream of the rivers is reflected in the size of beaver dams and ponds. The beaver dams and ponds are slightly larger in the sections of the rivers with a relatively small average gradient than in the sections with a medium average gradient of the channel.
Perancangan Stadion Sepak Bola Di Kabupten Garut Melalui Pendekatan Estetika Struktur
Authors: Rikhardi Andre
Published: July 2023

Kabupaten Garut merupakan Kabupaten di Provinsi Jawa Barat yang saat ini sedang berkembang. Dalam perkembangannya Kabupaten Garut membutuhkan fasilitas olahraga berupa stadion sepak bola yang dapat mengakomodasi kegiatan masyarakat dan juga sebagai home base dari tim Persatuan Sepakbola Indonesia Garut (disingkat PERSIGAR) yang saat ini bermain di divisi 3 Liga Indonesia. Tidak memiliki fasilitas stadion sepak bola yang layak menurut FIFA dan PSSI, sehingga membuat tim Persigar tidak dapat naik ke divisi selanjutnya. Untuk itu perlu adanya perancangan stadion sepak bola yang tidak hanya menjadi sarana olah raga namun juga sebagai sarana rekreasi masyarakat. Perancangan Stadion Sepak Bola dengan tema Estetika Struktur yang dimana rancangan stadion menerapkan sistem struktur membran sebagai penutup atap dan skins yang dipadukan dengan mega kolom beton precast yang membentuk kujang. Rancangan stadion sepak bola ini difokuskan pada desain yang di hasilkan melalui estetika struktur dari sistem struktur membrane tersebut.
Fasilitas Akomodasi Bagi Wisatawan Pantai Pangandaran Dengan Pendekatan Sense Of Place Yang Diaplikasikan Pada Bentuk Bangunan
Authors: Puspitasari Chintia
Published: July 2023

Kabupaten Pangandaran di Jawa Barat merupakan wilayah yang memiliiki potensi pariwisata yang terkenal dan juga ramai dikunjungi oleh para wisatawan baik lokal maupun internasional. Salah satu daya Tarik wisata yang paling digemari adalah pantai Pangandaran karena didukung dengan potensi alam yang unik serta adanya objek wisata lain di sekitarnya. Seperti, diantaranya adalah kawasan hutan lindung, penangkaran rusa, Batu Hiu, green canyon, pasir putih, dan sebagainya. Selain itu terdapat kegiatan tahunan yang sudah menjadi tradisi lokal memberikan daya tarik tersendiri, seperti festival layang-layang, upacara adat, hajat laut, sajen makanan laut, yang dapat menciptakan suasana keakraban keluarga. Potensi seperti ini seyogya nya didukung oleh pengembangan sarana rekreasi karena kebutuhan sarana tersebut diperlukan guna mewadahi perkembangan dan tingginya tingkat kedatangan para wisatawan, berdasarkan isu tersebut maka perlu disediakannya sebuah wadah yaitu berupa bangunan akomodasi seperti hotel resort, yang diharapkan dengan adanya bangunan hotel resort bisa menampung kegiatan wisatawan untuk rekreasi dan relaksasi di pantai Pangandaran. Fasilitas yang dirancang diharapkan dapat meningkatkan nilai ekonomi, mewadahi kebutuhan wisatawan dan meningkatkan citra sebuah kota
Penerapan Pleasure Pada Pusat Perbelanjaan Di Cianjur
Authors: Mutaqin Ahmad Fauzi
Published: July 2023

Pusat perbelanjaan, merupakan fasilitas untuk memenuhi kebutuhan hidup masyarakat. Pusat perbelanjaan kini semakin berkembang, sehingga kegiatan berbelanja dapat dipadukan dengan kegiatan pleasure, seperti berfoto, menonton, bermain dan sebagainya. Cianjur belum memiliki sebuah pusat perbelanjaan/shopping mall yang memfasilitasi kegiatan berbelanja hedonic maupun utilitarian, khususnya pada kegiatan pleasure. Maka jika fasilitas dan desain yang menarik tersebut sudah terpenuhi, akan membuat pusat perbelanjaan lebih ramai dikunjungi, khususnya bagi pusat perbelanjaan di Cianjur, yang belum memiliki seluruh fasilitas dan desain tersebut. Tujuan penulisan ini yaitu bagaimana penerapan/aplikasi pleasure pada desain perancangan fasilitas shopping mall di Cianjur. Metode pengumpulan data yaitu kualitatif dengan mengkaji berbagai jurnal sejenis. Penelitian menghasilkan penerapan/aplikasi Pleasure terhadap shopping mall di Cianjur, berupa fasilitas high tension and low tension, yaitu fasilitas hiburan dan entertainment seperti bioskop, foodcourt, arena bermain, karaoke, playground, lalu low tension, berbelanja, adanya ruang bersantai, foto sdutio, taman dalam ruangan dan rooftop.
KRITERIA RUANG YANG MAMPU MEMBERIKAN EDUKASI SAMPAH BAGI GENERASI MASA DEPAN
Authors: Ansori Isa , Dewiyanti Dhini
Published: July 2023

Sampah menjadi permasalahan utama bagi kota-kota di seluruh penjuru dunia karena kesulitan dalam hal pembuangan akhirnya. Ketiadaan lahan menjadi sebuah polemik berkepanjangan karena melibatkan berbagai macam isu seperti: lingkungan, sosial, psikologis, ekonomi, politik dan sebagainya. Permasalahan sampah harus diminimalisir sejak dini melalui edukasi mengenai sampah dan pengelolaannya. Edukasi dapat dilakukan melalui wadah bangunan yang mampu memberikan pengetahuan kepada masyarakat. Paper ini membahas pencarian kriteria ruang yang mampu memberikan edukasi mengenai sampah. Pencarian dilakukan melalui metode konten analisis berdasarkan studi literatur mengenai bangunan pengolahan sampah di luar. Hasil dari penelitian adalah mengenai gagasan ruang yang menstimuli terjadinya keingin-tahuan seseorang untuk bertindak.  Penelitian diharapkan dapat memberikan sebuah gagasan ide rancangan arsitektur mengenai bagunan pengelolaan sampah.
PENERAPAN HEALING ENVIRONMENT PADA RUANG LANDSCAPE PUSAT REHABILITASI SOSIAL ANAK KORBAN KEKERASAN
Authors: Ramadhanty Dea Maitsya , Natalia Tri Widianti
Published: July 2023

Anak adalah amanah serta aset bangsa yang akan memelihara, memperjuangkan, menjaga dan mempertahankan kekayaan bangsa. Kondisi jasmani serta rohani anak perlu dijaga agar mereka dapat tumbuh dan berkembang serta mendapatkan hak-haknya. Namun, kekerasan pada anak menjadi fenomena yang terus terjadi dan tidak berakhir. Kasus serta korbannya selalu meningkat setiap tahunnya. Kurangnya lingkungan yang mendukung penyembuhan di pusat rehabilitasi membuat rehabilitasi terhadap anak kurang optimal. Oleh karena itu diperlukan lingkungan bagi korban kekerasan pada anak untuk membantu proses penyembuhan fisik dan psikologi melalui pendekatan tema healing environment. Lingkungan menjadi salah satu hal yang amat berperan penting   di   dalam   proses   rehabilitasi   dan   terciptanya   kesehatan   jiwa   manusia. Perancangan sebuah lingkungan cukup mempengaruhi kecepatan pemulihan pengguna. Lingkungan alam memiliki efek positif bagi kesehatan terutama kesehatan mental. Ekspresi desain dan kesehatan dalam lansekap dapat ditemukan dalam adanya taman penyembuhan atau healing garden, yaitu taman yang dengan cara berbeda dapat mempengaruhi pengunjung secara positif. Metoda penelitian ini menggunakan metoda kualitatif yang berfokus pada studi literatur serta jurnal penelitian teori sejenis. Hasil dari penelitian ini adalah menerapkan healing environment pada ruang landscape pusat rehabilitasi melalui aspek ruang luar sebagai lingkungan penyembuhan.
PENGGUNAAN RAMMED EARTH SEBAGAI SOLUSI MATERIAL RAMAH LINGKUNGAN
Authors: Naufal Maulana Farras , Abioso Wanita Subadra
Published: July 2023

Rammed Earth mempunyai sejarah yang cukup panjang dan dianggap berhasil. Banyak bangunan-bangunan bersejarah yang bahkan sudah diakui sebagai warisan dunia menggunakan Rammed Earth sehingga dianggap sebagai alternatif baru dan juga inovasi yang sukses. Kekuatan yang dimilikinya menjadikan bangunan memiliki umur yang panjang. Teknik pembuatannya yang terbilang kuno namun dinilai berkelanjutan dan ramah lingkungan sehingga menjadi solusi dalam perkembangan pembangunan yang semakin pesat mengingat kondisi saat ini bumi harus diperhatikan sebaik mungkin dengan lebih melihat sustainabilitynya. Rammed Earth sendiri diklasifikasikan secara general menjadi Rammed Earth stabil dan tidak stabil berdasar bahan pengikat yang digunakan. Karakteristiknya yang dinilai ramah lingkungan cukup menarik untuk dipelajari sehingga penelitian ini diharapkan dapat memberikan gagasan dan jawaban dalam segala hal yang terkait seputar perancangan dan Rammed Earth itu sendiri.
PERENCANAAN RUANG KOMUNAL PADA AREA RETAIL STASIUN GARUT KOTA
Authors: Nur Syauqi Imam Dzaki , Abioso Wanita Subadra
Published: July 2023

Stasiun Garut Kota yang terletak di Kecamatan Garut Kota merupakan salah satu stasiun yang direaktivasi sebagai pusat kegiatan kawasan yang berorientasi pada transportasi publik. Belum adanya area retail di kawasan stasiun menjadi salah satu masalah perancangan. Mengingat lokasinya berada di dalam kawasan stasiun, penataan area retail perlu diperhatikan agar terciptanya ruang komunal yang mampu mewadahi aktivitas pengunjung retail tanpa mengganggu aktivitas pengunjung stasiun. Metode yang dilakukan dalam penelitian ini yaitu metode kualitatif dengan mengkaji beberapa jurnal terkait. Hasil dari penelitian ini berupa desain perencanaan ruang komunal pada area retail Stasiun Garut Kota. Desain yang terbentuk merupakan hasil penggabungan prinsip perencanaan ruang komunal serta prinsip perencanaan retail.
STUDI PEMETAAN ZONA PEDAGANG PASAR CICADAS BANDUNG
Authors: - Syadriyansyah
Published: July 2023

Pasar tradisional yang baik, mampu memperlihatkan sebuah wajah kota karena pada lokasi itulah, terjadi perbauran masyarakat yang berlangsung secara alamiah. Namun kenyataan di Indonesia, wajah pasar tradisional yang ada, sebagian besar justru memperlihatkan suasana yang memperlihatkan kekumuhan kawasan, disertai dengan bau dan pemandangan pedagang kaki lima yang mengurangi nilai estetis. Kondisi tersebut terkadang diperparah dengan tingkat kemacetan pada area pasar. Diperlukan sebuah solusi dalam hal peremajaan pasar dengan mengikutsertakan pedagang kaki lima yang sebaiknya juga diberi tempat layak. Penelitian ini merupakan sebuah studi pemetaan terhadap kelompok pedagang kaki lima yang terdapat di sepanjang Jalan Cicadas, Bandung. Melalui metoda pengamatan, pencatatan dan penggambaran lokasi yang dilakukan selama beberapa hari, didapatkan hasil berupa zona-zona kelompok pedagang Pasar Cicadas.
STUDI PENERAPAN WAYFINDING PADA ARSITEKTUR
Authors: Azis Fareish Abdul , Dewiyanti Dhini , Imaniar Laili Nur
Published: July 2023

Wayfinding dalam dunia arsitektur merupakan hal yang sangat dibutuhkan. Pengguna bangunan harus memiliki orientasi yang jelas mengenai posisi dan arah tujuannya sehingga akan merasa nyaman. Kehilangan orientasi bagi pengguna bangunan akan berdampak pada timbulnya rasa stress. Paper ini merupakan sebuah studi untuk pencarian pengertian mengenai wayfinding dan bagaimana penerapannya dalam desain bangunan. Studi dilakukan melalui kajian sejumlah pustaka. Signage menjadi cara untuk mengaplikasikan wayfinding. Bentuk signage bisa berupa piktogram, grafik visual, maupun papan penunjuk arah atau informasi. Hasil telaah mengenai wayfinding dapat menjadi arahan bagi desain yang akan dirancang dengan menggunakan tema wayfinding sebagai pendekatannya.
PERANCANGAN CONVENTION CENTRE DI GEDEBAGE DENGAN TEMA ESTETIKA DALAM STRUKTUR
Authors: Firdaus Ivan , Harapan Andi
Published: July 2023

Kegiatan konvensi merupakan salah satu kegiatan yang sangat berguna untuk meningkatkan perekonomian dan kemajuan suatu kota. Gedung konvensi merupakan salah satu wadah kegiatan pertemuan, yang juga dapat berfungsi untuk meningkatkan kepercayaan dunia terhadap Indonesia sebagai salah satu destinasi kegiatan Meeting, Incentive, Convention and Exhibition (MICE). Tujuan perancangan adalah untuk menghadirkan bangunan berbentang lebar dengan isu estetika struktur. Metode pendekatan dilakukan melalui 3 (tiga) tahap: kajian teori, tinjauan lapangan dan pemodelan desain. Hasil dari pendekatan desain adalah berupa rancangan yang memiliki nilai estetika, sesuai dengan peraturan setempat dan juga memenuhi kaidah untuk fungsi sebagai gedung konvensi.
RONA FISIK RUANG SOSIAL PENGUNJUNG MASJID AL HASANAH BANDUNG PASCA PANDEMI
Authors: Lestari Salsadilla Mutiara , Natalia Tri Widianti , Dewiyanti Dhini , Aditya Nova Chandra
Published: July 2023

Masjid Al Hasanah merupakan masjid jami yang sering digunakan oleh masyarakat muslim sekitar Sadang Serang, Kota Bandung. Masjid ini dijadikan tempat untuk ibadah terutama sholat jumat, kegiatan pengajian, dan kegiatan sosial. Semenjak pandemi Covid 19 fasilitas masjid terkena dampak dikarenakan pembatasan kunjungan sehingga efektifitas ruang pada masjid berkurang. Tujuan dari penelitian ini adalah untuk mengetahui rona fisik ruangan masjid terutama pada ruang sosial masjid pasca pandemi dengan melakukan pengamatan terhadap ruang-ruang sosial yang ada pada Masjid Jami Al Hasanah yang berpengaruh terhadap perilaku seseorang di dalamnya. Hasil penelitian yang didapat bahwa ruang sosial pada Masjid Al Hasanah dapat memberikan peran penting dalam berinteraksi setelah melaksanakan ibadah dan kegiatan yang dilakukan didalamnya, sehingga ruang sosial pada Masjid Jami Al Hasanah ini dapat menjadi ruang untuk menampung kegiatan bersosialisasi dan berinteraksi atau tempat dilakukannya kegiatan sosial yang nyaman.
DEFINISI KONSEP KREATIF DALAM PERANCANGAN DIGITAL CREATIVE CENTER
Authors: Fitri Cici Nabila , Dewiyanti Dhini , Irmansyah Firman
Published: July 2023

Creative center merupakan sarana untuk menyalurkan dan meningkatkan kreativitas masyarakat. Pada era digitalisasi saat ini, industri kreatif mulai bergeser ke arah digital, terlihat semakin banyak pelaku industri kreatif dalam bidang digital. Namun karena industri ini terbilang baru di Indonesia, sehingga beberapa fasilitas yang tersedia belum sesuai. Dibutuhkan ruang publik yang dapat dijadikan sebagai tempat pelatihan dan pengembangan industri digital kreatif salah satu solusinya yaitu dengan menyediakan digital creative center. Penelitian bertujuan untuk memahami konsep ruang yang sesuai dengan kebutuhan pelaku kreatif digital. Metode dilakukan melalui kajian pustaka dan wawancara terhadap komunitas digital kreatif. Hasil analisis mengungkapkan kesimpulan mengenai: 1) Fasilitas yang sesuai bagi pelaku digital creative; 2) kriteria ruangan yang memenuhi kebutuhan pelaku digital creative; 3) Desain bangunan yang dapat meningkatkan kreativitas.
PERENCANAAN LEMBAGA PEMASYARAKATAN WANITA YANG HUMANIS
Authors: Zen Qony Sya'bany , Dewiyanti Dhini , Aditya Nova Chandra
Published: July 2023

Perubahan istilah penjara menjadi lembaga pemasyarakatan bertujuan agar warga binaan yang sedang berada di dalamnya, dapat dihargai sebagai manusia dan kelak menjadi manusia yang lebih baik. Guna menunjang kegiatan membina, diperlukan fasilitas Lembaga Pemasyarakatan (Lapas) yang dapat mendukung kebutuhan kegiatan. Tujuan penulisan naskah ini adalah untuk memperlihatkan sebuah proses pencarian studi guna mendapatkan pemahaman mengenai konsep humanis yang dapat diterapkan pada perancangan lapas, khususnya lapasnya perempuan. Melalui kajian pustaka berupa pemahaman terhadap gambar-gambar yang diperoleh melalui pencarian secara daring, dilakukan kegiatan memilah dan memilih informasi yang berkaitan dengan lapas yang humanis. Hasil studi memperoleh pemahaman mengenai gambaran sebuah lapas dalam penyediaan fasilitas yang dianggap dapat memanusiakan manusia, dalam hal ini adalah para warga binaan.
DESAIN RUANG TERAPI WICARA ANAK PENYANDANG AUTISME
Authors: Hidayat Syarip , Natalia Tri Widianti
Published: July 2023

Autism atau autisme merupakan istilah yang pertama kali dipopulerkan pada tahun 1943 oleh Leo Kanner, seorang psikiater dari John Hopkins University. Dikutip dari CNN Indonesia (2017) peningkatan pesat jumlah penyandang autisme tidak diimbangi dengan peningkatan pengadaan fasilitas-fasilitas yang memadai bagi para penyandang autisme. Salah satu bahan pertimbangan perencanaan dan perancangan ruang yang dapat menciptakan lingkungan yang nyaman dan ramah terhadap anak penyandang autisme yaitu aspek pemilihan material yang tepat. Tujuan penulisan jurnal ini adalah untuk mengetahui kriteria ruang terapi wicara untuk anak penyandang autisme dengan metode penelitian korelasi karena berisi penjelasan aspek-aspek ruang yang berpengaruh terhadap daya dukung komunikasi anak penyandang autisme.
PENERAPAN TEMA CULTURE AND ART PADA MUSEUM AGUNG BUNG KARNO DI NITI MANDALA RENON
Authors: Permana Alvika , Martana Salmon Priaji
Published: July 2023

Museum Agung Bung Karno yang bearada di Niti Mandala Renon merupakan museum Sukarno satu– satunya yang berada di kota Denpasar Bali. Museum ini berukuran kurang lebih 400meter persegi. Museum ini merupakan museum swasta atau milik pribadi. Dengan dimensi ruang yang terbatas, museum ini bisa dikatakan tidak memenuhi standar, dilihat dari tidak adanya lahan parkir untuk kendaraan roda empat pada bangunan Agung Bung Karno juga belum memenuhi standar bangunan bagi bangunan museum. Karena luas lahan bangunan pada bangunan museum ini terlalu kecil dan tidak seimbang dengan banyaknya benda koleksi yang berada di dalamnya hal ini pula yang membuat bagian dalam museum ini terasaa semerawut dan banyak barang barang yang bertumpukan di lantai. Dari faktor tersebut bangunan museum Agung Bung Karno ini perlu di lakukan perancangan ulang yang sesuai dengan fungsinya yaitu museum.
ANALISIS FASILITAS PARKIR PADA POLIKLINIK RSHS DAN POLIKLINIK HALMAHERA
Authors: Farhannisa Amilia Najma , Natalia Tri Widianti
Published: July 2023

Parkir merupakan salah satu aspek yang tidak bisa lepas dari kebutuhan transportasi. Permasalahan yang seringkali terjadi di Indonesia adalah pada ketidaktersediaan jumlah parkir yang memadai pada bangunan-bangunan publik. Akibatnya kendaraan memarkirnya pada badan jalan yang berdampak pada kemacetan lalu lintas. Fasilitas kesehatan merupakan salah satu bangunan publik yang terlihat seringkali menyebabkan kemacetan lalu lintas di sekitarnya akibat parkir yang tidak mencukupi. Dalam penelitian ini, metode yang digunakan adalah metode kualitatif dan analisis deskriptif dengan mengkaji standar parkir yang ada, melakukan observasi (studi banding), dan menganalisis data. Tujuan dari penelitian ini adalah untuk mengetahui kesesuaian fasilitas pada Poliklinik RSHS dan Poliklnik Halmahera dengan standar-standar yang ada. Hasil dari penelitian ini menyatakan bahwa kedua poliklinik memiliki nilai rata-rata 83% yang artinya hampir sepenuhnya sesuai dengan standar. Meskipun masih ada beberapa standar yang belum sesuai, namun konflik yang timbul dinilai masih tidak terlalu berdampak signifikan.
The Impact of Pediatric CKD on Educational and Employment Outcomes
Authors: Harshman Lyndsay A. , Ward Ryan C. , Matheson Matthew B. , Dawson Anne , Kogon Amy J. , Lande Marc B. , Molitor Stephen J. , Johnson Rebecca J. , Wilson Camille , Warady Bradley A. , Furth Susan L. , Hooper Stephen R.
Published: July 2023

Key Points

This study evaluates educational and employment outcomes in patients with pediatric kidney disease and assesses predictors of educational attainment and employment in young adulthood.

Despite high rates of high school graduation, nearly 20% of patients with CKD are unemployed or receiving disability at long-term follow-up.

Background

Pediatric patients with CKD are at risk for neurocognitive deficits and academic underachievement. This population may be at risk for lower educational attainment and higher rates of unemployment; however, published data have focused on patients with advanced CKD and exist in isolation from assessment of neurocognition and kidney function.

Methods

Data from the CKD in Children (CKiD) cohort study were used to characterize educational attainment and employment status in young adults with CKD. We used ratings of executive function as a predictor of future educational attainment and employment status. Linear regression models predicted the highest grade level completed. Logistic regression models predicted unemployment.

Results

A total of 296 CKiD participants aged 18 years or older had available educational data. In total, 220 of 296 had employment data. By age 22 years, 97% had completed high school and 48% completed 2+ years of college. Among those reporting employment status, 58% were part-time or full-time employed, 22% were nonworking students, and 20% were unemployed and/or receiving disability. In adjusted models, lower kidney function (P = 0.02), worse executive function (P = 0.02), and poor performance on achievement testing (P = 0.004) predicted lower grade level completed relative to expectation for age.

Conclusions

CKiD study patients appear to have a better high school graduation rates (97%) than the adjusted national high school graduation rate (86%). Conversely, roughly 20% of participants were unemployed or receiving disability at study follow-up. Tailored interventions may benefit patients with CKD with lower kidney function and/or executive function deficits to optimize educational/employment outcomes in adulthood.
Deep Learning on Electrocardiograms for Prediction of In-hospital Intradialytic Hypotension in Patients with ESKD
Authors: Vaid Akhil , Takkavatakarn Kullaya , Divers Jasmin , Charytan David M. , Chan Lili , Nadkarni Girish N.
Published: July 2023

Key Points

Intradialytic hypotension is common in patients who are on hemodialysis.

We applied deep learning techniques to ECGs to predict patients at risk of IDH. The performance of the model was good with an AUC of 0.763 and AUPRC of 0.35.
Farmers and Health Care Reform: A Challenge and Opportunity for Extension
Authors: Inwood Shoshanah , Braun Bonnie , Knudson Alana , Parker Jason
Published: July 2023

The Affordable Care Act (ACA) presents both opportunities and challenges for farmers. There is a great deal of variation in how states are implementing the ACA, which creates confusion for individuals and businesses trying to understand and evaluate health insurance options. To assist farmers and farm workers with navigating ACA reforms, Extension can work across program areas and leverage their network of farm technical assistance providers and non-profits to enhance outreach and program efforts. Extension tax schools and wider adoption of the Smart Choice Health Insurance - Farm Families can expand the portfolio of tools available for working with farmers.
The Systematic Screening and Assessment Method: An Introduction and Application
Authors: Downey Laura , Peterson Donna , LeMenestrel Suzanne , Leatherman JoAnne
Published: July 2023

The Systematic Screening and Assessment method (SSA) could be a useful approach to identifying Extension programs being implemented, to describing the nature of those programs, and to highlighting those that have proven effective. After a general discussion of SSA, we provide an application of SSA as recently used to identify 4-H Healthy Living programs with evidence of improving diet; physical activity; and alcohol, tobacco, and other drug use prevention outcomes. Our goal is to increase awareness about SSA and to demonstrate that it can be used to expand the knowledge and reach of Extension programs with evidence of impact.
IT Workforce Development: A Family and Consumer Sciences Community Capacity Model
Authors: Meszaros Peggy , Kimbrell Monica , Swenson Andrea
Published: July 2023

This article examines Extension professionals building community capacity in 10 counties across five Appalachian states in response to the talent crisis in the United States information technology (IT) workforce. The goal has been to transfer IT knowledge and create a supportive environment to foster interest in IT careers among underserved girls in Appalachian communities. The project, funded by the National Science Foundation, incorporates the example of Family and Consumer Sciences agents modeling the structure of Extension. Extension professionals can use this model to pioneer workforce development and community change initiatives.
Developing a Mobile Extension Course for Youth Livestock Producers
Authors: Weitzenkamp Deborah , Dam Karna , Chichester Lindsay
Published: July 2023

The 4-H Livestock Quality Assurance course is a mobile Extension course for youth and youth leaders. In 3 years of implementation, over 6,600 participants from 16 states have learned about good production practices for animal agriculture through the innovative online Nebraska Livestock Quality Assurance course. By evaluating the needs of our youth and capitalizing upon content area experts from across the state, we are able to provide the best content to all youth, 24X7.
Can an Immersion in Wellness Camp Influence Youth Health Behaviors?
Authors: Olsen Elizabeth , Litchfield Ruth , Foster Randal , Foster Lorraine , Campbell Christina
Published: July 2023

Summer 4-H camps present an untapped opportunity for advancement of mission mandates. The project reported here immersed campers in healthy living experiential learning. The goal was to improve selfefficacy and health behaviors related to nutrition and physical activity. Data was collected from enrolled campers through multiple survey tools. A total of 74 campers completed baseline surveys during summer 2012; 6-month follow-up rate was 72%. Camp improved intervention campers' nutrition knowledge (p<0.10) and home food environment (p<0.05). Results suggest experiential learning/immersion opportunities in nutrition, culinary, and gardening may encourage positive health behaviors and influence the home food environment.
What Is Your Library Worth? Extension Uses Public Value Workshops in Communities
Authors: Haskell Jane , Morse George
Published: July 2023

Public libraries are seeing flat or reduced funding even as demands for new services are increasing. Facing an identical problem, Extension developed a program to identify the indirect benefits to non-participants of Extension programs in order to encourage their public funding support. This educational approach was customized to public libraries and piloted with 15 libraries. Evaluations demonstrated that the approach was popular and effective in changing local practices. Strategies are shared for customizing Extension's public value program so that any public program can articulate short private and public value statements.
Early Detection Rapid Response Program Targets New Noxious Weed Species in Washington State
Authors: Andreas Jennifer , Halpern Alison , Descamp Wendy , Miller Timothy
Published: July 2023

Early detection, rapid response is a critical component of invasive plant management. It can be challenging, however, to detect new invaders before they become established if landowners cannot identify species of concern. In order to increase awareness, eye-catching postcards were developed in Washington State as part of a noxious weed educational campaign. Plant identification, potential impacts, and current distributions are provided in a simple format for easy information consumption. Postcards are distributed across the state at various venues, thereby increasing the general public's exposure to little known but high risk species.
Using Ripple Effect Mapping to Evaluate Program Impact: Choosing or Combining the Methods That Work Best for You
Authors: Emery Mary , Higgins Lorie , Chazdon Scott , Hansen Debra
Published: July 2023

A mind mapping approach to evaluation called Ripple Effects Mapping (REM) has been developed and used by a number of Extension faculty across the country recently. This article describes three approaches to REM, as well as key differences and similarities. The authors, each from different land-grant institutions, believe REM is an effective way to document direct and indirect impacts of community development programs while providing an opportunity for reflection and inspiration to program participants.
Injecting Extension into the American Zeitgeist
Authors: Stafne Eric
Published: July 2023

Extension is a product of times past and needs to be updated and upgraded for today's world. "Zeitgeist" is a German term that encompasses the moral, cultural, and intellectual climate that exists within a certain time and place. Defining how this relates to Extension is not easy. Extension should examine popular culture and realize that story-driven and relatable visual media, such as television and film, are what capture the public interest. Extension must tap into that to assimilate with the younger demographics. Ultimately, we in Extension are responsible for telling and being the heroes of our own story.
Opportunities for Extension: Linking Health Insurance and Farm Viability
Authors: Inwood Shoshanah
Published: July 2023

Extension has a crucial role to play in educating Americans about their new choices under the Patient Protection and Affordable Care Act (ACA). Health insurance is a cross-cutting issue that touches on multiple Extension program areas. This article draws on national survey research and interviews with farmers at the rural-urban-interface conducted prior to the ACA to consider the potential influence of the ACA on the food and agriculture sector and the role of both Agriculture and Consumer and Family Science Extension programing in assisting farmers with ACA reforms.
Determining Extension's Role in Controversial Issues: Content, Process, Neither, or Both?
Authors: Georlich Dan , Walker Martha
Published: July 2023

Controversial issues offer Extension faculty opportunities to facilitate community dialogue and apply conflict resolution strategies to help communities achieve higher ground. Handled appropriately, the long-term benefits to the community, the Extension organization, and the faculty member of facilitating public issues outweigh the costs. This article explores Extension's place in facilitating public issues dialogue and provides an initial first step in the decision-making process regarding what Extension's role should be. An approach is proposed that can help faculty decide whether to respond to an issue with content, process, or a more comprehensive approach
Building Sustainability in Gas- and Oil-Producing Communities
Authors: Romich Eric , Ellzey Nancy , Moss Myra , Bond Cindy , Civittolo David
Published: July 2023

Extension can play a significant role in addressing the rapid development and associated impacts that can occur in oil- and gas- producing communities. Through quantitative longitudinal analysis and research-based sustainable planning, Extension can assist rural communities in Ohio to be better equipped to maximize resources, manage change, and make informed decisions affecting their residents. This article provides a framework for an effective program focused on shale development planning and offers a context for massive change taking place in rural communities across the nation.
Using Evaluation to Guide and Validate Improvements to the Utah Master Naturalist Program
Authors: Casanova Mark
Published: July 2023

Integrating evaluation into an Extension program offers multiple opportunities to understand program success through achieving program goals and objectives, delivering programming using the most effective techniques, and refining program audiences. It is less common that evaluation is used to guide and validate the effectiveness of program revision. Early evaluation results from Utah Master Naturalist Watersheds classes were used to make specific, targeted program revisions, and significant increases in recent evaluation results validated that the revisions were successful. Using evaluation in this way conserves time, effort, and resources, and helps achieve a high level of program success expected from Extension professionals.
Hands-On Training Emphasized in the Oregon Master Beekeeper Program
Authors: Breece Carolyn , Sagili Ramesh
Published: July 2023

Honey bee colony declines have garnered immense public interest, and consequently there is a significant demand for the dissemination of apicultural information. The Oregon Master Beekeeper Program was developed in response to this increased interest in bees and beekeeping and a demand for a credible educational program for new beekeepers. The program focuses on hands-on training by matching students with volunteer mentors. Upon completion of the beginning (Apprentice) level, trained students may enroll in the advanced (Journey) level. This program has gained popularity and strives to educate beekeepers to promote sustainable beekeeping in the Pacific Northwest.