bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary figure legends from Breast Tumor Kinase (Brk/PTK6) Is Induced by HIF, Glucocorticoid Receptor, and PELP1-Mediated Stress Signaling in Triple-Negative Breast Cancer
Authors: Regan Anderson Tarah M. , Ma Shi Hong , Raj Ganesh V. , Cidlowski John A. , Helle Taylor M. , Knutson Todd P. , Krutilina Raisa I. , Seagroves Tiffany N. , Lange Carol A.
Published: April 2023

Figure legends for supplementary figures 1 and 2.
Supplementary Figure 1 from Breast Tumor Kinase (Brk/PTK6) Is Induced by HIF, Glucocorticoid Receptor, and PELP1-Mediated Stress Signaling in Triple-Negative Breast Cancer
Authors: Regan Anderson Tarah M. , Ma Shi Hong , Raj Ganesh V. , Cidlowski John A. , Helle Taylor M. , Knutson Todd P. , Krutilina Raisa I. , Seagroves Tiffany N. , Lange Carol A.
Published: April 2023

Dex regulation of Brk mRNA and protein in TNBC cell lines and explants.
Supplementary Figure Legends from Rho GTPase Transcriptome Analysis Reveals Oncogenic Roles for Rho GTPase-Activating Proteins in Basal-like Breast Cancers
Authors: Lawson Campbell D. , Fan Cheng , Mitin Natalia , Baker Nicole M. , George Samuel D. , Graham David M. , Perou Charles M. , Burridge Keith , Der Channing J. , Rossman Kent L.
Published: April 2023

Figure Legends for Supplementary Figures S1-S4
Supplementary Table 1 from Gender-Specific Molecular and Clinical Features Underlie Malignant Pleural Mesothelioma
Authors: De Rienzo Assunta , Archer Michael A. , Yeap Beow Y. , Dao Nhien , Sciaranghella Daniele , Sideris Antonios C. , Zheng Yifan , Holman Alexander G. , Wang Yaoyu E. , Dal Cin Paola S. , Fletcher Jonathan A. , Rubio Renee , Croft Larry , Quackenbush John , Sugarbaker Peter E. , Munir Kiara J. , Battilana Jesse R. , Gustafson Corinne E. , Chirieac Lucian R. , Ching Soo Meng , Wong James , Tay Liang Chung , Rudd Stephen , Hercus Robert , Sugarbaker David J. , Richards William G. , Bueno Raphael
Published: April 2023

Whole genome sequencing data analysis of 10 MPM tumor and matched DNA generated by Complete Genomics platform
Supplementary Figures: Lack of p53 Augments Anti-Tumor Functions in Cytolytic T Cells from Lack of p53 Augments Antitumor Functions in Cytolytic T Cells
Authors: Banerjee Anirban , Thyagarajan Krishnamurthy , Chatterjee Shilpak , Chakraborty Paramita , Kesarwani Pravin , Soloshchenko Myroslawa , Al-Hommrani Mazen , Andrijauskaite Kristina , Moxley Kelly , Janakiraman Harinarayanan , Scheffel Matthew J. , Helke Kristi , Armenson Kent , Palanisamy Viswanathan , Rubinstein Mark P. , Mayer Elizabeth-Garrett , Cole David J. , Paulos Chrystal M. , Voelkel-Johnson Christina , Nishimura Michael I. , Mehrotra Shikhar
Published: April 2023

Details for comparative characterization of phenotype and anti-tumor function between the p53-KO vs. WT T cells are included.
Supplementary Figure 2 from Inhibition of MUC1-C Suppresses MYC Expression and Attenuates Malignant Growth in KRAS Mutant Lung Adenocarcinomas
Authors: Bouillez Audrey , Rajabi Hasan , Pitroda Sean , Jin Caining , Alam Maroof , Kharbanda Akriti , Tagde Ashujit , Wong Kwok-Kin , Kufe Donald
Published: April 2023

Effects of targeting MUC1-C in non-KRAS mutant NSCLC cells.
Supplementary Figure 1 from Inhibition of MUC1-C Suppresses MYC Expression and Attenuates Malignant Growth in KRAS Mutant Lung Adenocarcinomas
Authors: Bouillez Audrey , Rajabi Hasan , Pitroda Sean , Jin Caining , Alam Maroof , Kharbanda Akriti , Tagde Ashujit , Wong Kwok-Kin , Kufe Donald
Published: April 2023

Silencing MUC1-C suppresses MYC levels.
Supplementary Table S4 from Ovarian Cancers Harboring Inactivating Mutations in CDK12 Display a Distinct Genomic Instability Pattern Characterized by Large Tandem Duplications
Authors: Popova Tatiana , Manié Elodie , Boeva Valentina , Battistella Aude , Goundiam Oumou , Smith Nicholas K. , Mueller Christopher R. , Raynal Virginie , Mariani Odette , Sastre-Garau Xavier , Stern Marc-Henri
Published: April 2023

The list of genes differentially expressed in CDK12 inactivated tumors (raw p-values are shown)
Supplementary Figure S8 from miR-1298 Inhibits Mutant KRAS-Driven Tumor Growth by Repressing FAK and LAMB3
Authors: Zhou Ying , Dang Jason , Chang Kung-Yen , Yau Edwin , Aza-Blanc Pedro , Moscat Jorge , Rana Tariq M.
Published: April 2023

LAMA3 and LAMC2 Expression Do Not Predict Survival of NSCLC Patients with Tumors Expressing a KRAS Gene Signature.
Supplementary Figures from Ovarian Cancers Harboring Inactivating Mutations in CDK12 Display a Distinct Genomic Instability Pattern Characterized by Large Tandem Duplications
Authors: Popova Tatiana , Manié Elodie , Boeva Valentina , Battistella Aude , Goundiam Oumou , Smith Nicholas K. , Mueller Christopher R. , Raynal Virginie , Mariani Odette , Sastre-Garau Xavier , Stern Marc-Henri
Published: April 2023

22 Supplementary Figures: CDK12 mutations detected in TCGA (S1-2) and in-house (S3) tumors; TDs in CDK12-mutated tumors (S4); Microhomology at the breakpoints and the size of TDs in CDK12-mutated tumors (S5); Copy number alteration profiles of eaPEO14 and PEO14 samples (S6); CDK12 mutation in PD3722a sample (S7); TDs in 25 TCGA cases with WGS (S8); Tumors with frequent TDs in the TCGA cohorts (S9); TD-plus phenotype in breast and prostate cancers (S10); GC content and mutation rate in TDs (S11); Recurrence analysis of TDs (S12); Replication time and CTCF binding sites at TDs (S13). TDs and gene loci (S14); Genomic signatures of HRD and CDK12 TD-plus phenotype (S15); Copy number profiles in tumors with CDK12 TD-plus phenotype (S16); CDK12 mutated tumors and mesenchymal subtype (S17); Molecular features of tumors with CDK12 TD plus phenotype (S18); Genes correlated to CDK12 (S19); Expression of ATM and CSTF3 and RPRD1A in a CDK12 context (S20); Alteration profiles of SKOV3 cell line (S21); The size of microhomology at the breakpoint junctions (S22).
Supplementary Figure S3 from miR-1298 Inhibits Mutant KRAS-Driven Tumor Growth by Repressing FAK and LAMB3
Authors: Zhou Ying , Dang Jason , Chang Kung-Yen , Yau Edwin , Aza-Blanc Pedro , Moscat Jorge , Rana Tariq M.
Published: April 2023

miR-1298 expression is lower in KRASMUT NSCLC cell lines but not dependent on mutant KRAS expression.
Supplementary Figures S1-S7 from Tissue Factor Induced by Epithelial–Mesenchymal Transition Triggers a Procoagulant State That Drives Metastasis of Circulating Tumor Cells
Authors: Bourcy Morgane , Suarez-Carmona Meggy , Lambert Justine , Francart Marie-Emilie , Schroeder Hélène , Delierneux Céline , Skrypek Nicolas , Thompson Erik W. , Jérusalem Guy , Berx Geert , Thiry Marc , Blacher Silvia , Hollier Brett G. , Noël Agnès , Oury Cécile , Polette Myriam , Gilles Christine
Published: April 2023

Supplementary Figure S1: Optimization of the triple immunostaining on different cell lines with known status of cytokeratins, TF and vimentin expression. Supplementary Figure S2: TF expression and pro-coagulant activity of EMT inducible cell lines. Supplementary Figure S3: Impact of TF blocking antibody on coagulant activity. Supplementary Figure S4: Regulation of TF by EMT transcription factors. Supplementary Figure S5: Induction of TF after de novo expression of Snail in MDA-MB-468. Supplementary Figure S6: Validation of TF shRNA. Supplementary Figure S7: Presence of fibrin fibers around lung colonizing MDA-MB-231 cells as revealed by transmission electron microscopy.
Supplementary Figure S4 from Small-Molecule Prodigiosin Restores p53 Tumor Suppressor Activity in Chemoresistant Colorectal Cancer Stem Cells via c-Jun-Mediated ΔNp73 Inhibition and p73 Activation
Authors: Prabhu Varun V. , Hong Bo , Allen Joshua E. , Zhang Shengliang , Lulla Amriti R. , Dicker David T. , El-Deiry Wafik S.
Published: April 2023

Prodigiosin-mediated anti-CRCSC effect involves p53 pathway restoration via p73.
Supplementary Figure S2 from Small-Molecule Prodigiosin Restores p53 Tumor Suppressor Activity in Chemoresistant Colorectal Cancer Stem Cells via c-Jun-Mediated ΔNp73 Inhibition and p73 Activation
Authors: Prabhu Varun V. , Hong Bo , Allen Joshua E. , Zhang Shengliang , Lulla Amriti R. , Dicker David T. , El-Deiry Wafik S.
Published: April 2023

Prodigiosin targets CRCSC self-renewal in vivo.
Supplementary Figures 1 through 5 from EGF816 Exerts Anticancer Effects in Non–Small Cell Lung Cancer by Irreversibly and Selectively Targeting Primary and Acquired Activating Mutations in the EGF Receptor
Authors: Jia Yong , Juarez Jose , Li Jie , Manuia Mari , Niederst Matthew J. , Tompkins Celin , Timple Noelito , Vaillancourt Mei-Ting , Pferdekamper AnneMarie Culazzo , Lockerman Elizabeth L. , Li Chun , Anderson Jennifer , Costa Carlotta , Liao Debbie , Murphy Eric , DiDonato Michael , Bursulaya Badry , Lelais Gerald , Barretina Jordi , McNeill Matthew , Epple Robert , Marsilje Thomas H. , Pathan Nuzhat , Engelman Jeffrey A. , Michellys Pierre-Yves , McNamara Peter , Harris Jennifer , Bender Steven , Kasibhatla Shailaja
Published: April 2023

This file shows the Supplementary figures. Figure S1 shows the chemical structure of EGF816 and its binding to EGFR T790M mutant. Figure S2 shows the tolerability of EGF816 in the in vivo xenograft models. Figure S3 shows the in vivo PK and PD after a single dose of EGF816. Figure S4 shows the selectivity profile of EGF816 in the kinome tree. Figure S5 shows the morphology of EGF816 resistance clones.
Supplementary Table I and II from PRC2 Epigenetically Silences Th1-Type Chemokines to Suppress Effector T-Cell Trafficking in Colon Cancer
Authors: Nagarsheth Nisha , Peng Dongjun , Kryczek Ilona , Wu Ke , Li Wei , Zhao Ende , Zhao Lili , Wei Shuang , Frankel Timothy , Vatan Linda , Szeliga Wojciech , Dou Yali , Owens Scott , Marquez Victor , Tao Kaixiong , Huang Emina , Wang Guobin , Zou Weiping
Published: April 2023

This is Supplementary Tables I and II Table 1: RT-PCR primers and ChIP primers Table 2: shRNA Sequences
Figure S2 from PRC2 Epigenetically Silences Th1-Type Chemokines to Suppress Effector T-Cell Trafficking in Colon Cancer
Authors: Nagarsheth Nisha , Peng Dongjun , Kryczek Ilona , Wu Ke , Li Wei , Zhao Ende , Zhao Lili , Wei Shuang , Frankel Timothy , Vatan Linda , Szeliga Wojciech , Dou Yali , Owens Scott , Marquez Victor , Tao Kaixiong , Huang Emina , Wang Guobin , Zou Weiping
Published: April 2023

Figure S2: Effects of H3K27me3 on Th1-type chemokine production in colon cancer cells
Supplementary Table 3 from A Small-Molecule Antagonist of the β-Catenin/TCF4 Interaction Blocks the Self-Renewal of Cancer Stem Cells and Suppresses Tumorigenesis
Authors: Fang Liang , Zhu Qionghua , Neuenschwander Martin , Specker Edgar , Wulf-Goldenberg Annika , Weis William I. , von Kries Jens P. , Birchmeier Walter
Published: April 2023

Table S3. Gene function clustering using the DAVID bioinformatics resources. Table S1. Gene function clustering using the DAVID bioinformatics resources.
Figure S1 from PRC2 Epigenetically Silences Th1-Type Chemokines to Suppress Effector T-Cell Trafficking in Colon Cancer
Authors: Nagarsheth Nisha , Peng Dongjun , Kryczek Ilona , Wu Ke , Li Wei , Zhao Ende , Zhao Lili , Wei Shuang , Frankel Timothy , Vatan Linda , Szeliga Wojciech , Dou Yali , Owens Scott , Marquez Victor , Tao Kaixiong , Huang Emina , Wang Guobin , Zou Weiping
Published: April 2023

Figure S1: Effects of the PRC2 complex on the IFNï�§-mediated Th1-type chemokine production in colon cancer cells
Supplementary Figure 3 from SIGMAR1 Regulates Membrane Electrical Activity in Response to Extracellular Matrix Stimulation to Drive Cancer Cell Invasiveness
Authors: Crottès David , Rapetti-Mauss Raphael , Alcaraz-Perez Francisca , Tichet Mélanie , Gariano Giuseppina , Martial Sonia , Guizouarn Hélène , Pellissier Bernard , Loubat Agnès , Popa Alexandra , Paquet Agnès , Presta Marco , Tartare-Deckert Sophie , Cayuela Maria Luisa , Martin Patrick , Borgese Franck , Soriani Olivier
Published: April 2023

Control experiments showing specificity of PLA assay between hERG and β1 integrin
Supplementary Figure 1 from SIGMAR1 Regulates Membrane Electrical Activity in Response to Extracellular Matrix Stimulation to Drive Cancer Cell Invasiveness
Authors: Crottès David , Rapetti-Mauss Raphael , Alcaraz-Perez Francisca , Tichet Mélanie , Gariano Giuseppina , Martial Sonia , Guizouarn Hélène , Pellissier Bernard , Loubat Agnès , Popa Alexandra , Paquet Agnès , Presta Marco , Tartare-Deckert Sophie , Cayuela Maria Luisa , Martin Patrick , Borgese Franck , Soriani Olivier
Published: April 2023

FDM induces a stable increase in hERG current in a Sig1R-dependent manner but does not alter channel maturation
Supplementary Table S3 from Loss of TGFβ Receptor Type 2 Expression Impairs Estrogen Response and Confers Tamoxifen Resistance
Authors: Busch Susann , Sims Andrew H. , Stål Olle , Fernö Mårten , Landberg Göran
Published: April 2023

Multivariate analysis of recurrence-free survival regarding prognostic information of SMAD2 phosphorylation.
Supplementary Figure Legends from Identification of the Cell-Intrinsic and -Extrinsic Pathways Downstream of EGFR and IFNγ That Induce PD-L1 Expression in Head and Neck Cancer
Authors: Concha-Benavente Fernando , Srivastava Raghvendra M. , Trivedi Sumita , Lei Yu , Chandran Uma , Seethala Raja R. , Freeman Gordon J. , Ferris Robert L.
Published: April 2023

Supplementary Figure Legends
Supplementary Figure S3 from SSBP1 Suppresses TGFβ-Driven Epithelial-to-Mesenchymal Transition and Metastasis in Triple-Negative Breast Cancer by Regulating Mitochondrial Retrograde Signaling
Authors: Jiang Hong-Lin , Sun He-Fen , Gao Shui-Ping , Li Liang-Dong , Huang Sheng , Hu Xin , Liu Sheng , Wu Jiong , Shao Zhi-Ming , Jin Wei
Published: April 2023

(A) The relative mtDNA content was analyzed by real-time PCR amplification of mtDNA encoded COX I and nuclear encoded GAPDH. (B) Statistical data of mitochondrial ROS generation in the indicated cells. (C) Western blot analysis of p-SMAD3 and SMAD3 expression in the indicated cells. (D) The migration abilities of indicated cell line were evaluated by Transwell assays in vitro. *** P < 0.005 compared with control. (E) Left: Control and CCCP-treated (20 μM for 2 h) MDA-MB-231 and MDA-MB-231shSSBP1 cells were incubated with or without added FK506 (10 nM). Total cellular protein fractions were subjected to western blot analysis using indicated antibodies. Right: Total cellular protein fractions of MDA-MB-231 cells transfected with CnA and treated with or without FK506 analyzed by western blot analysis using indicated antibodies. (F) Control and CCCP-treated (20 μM for 2 h) MDA-MB-231 and MDA-MB-231shSSBP1 cells were incubated with or without added FK506 (10 nM). Nuclear protein fractions were subjected to western blot analysis using indicated antibodies. (G) Western blot analysis of E-cadherin and Fibronectin expression in the indicated cells.
supplemental materials and methods from Calcium-Sensing Receptor Promotes Breast Cancer by Stimulating Intracrine Actions of Parathyroid Hormone–Related Protein
Authors: Kim Wonnam , Takyar Farzin M. , Swan Karena , Jeong Jaekwang , VanHouten Joshua , Sullivan Catherine , Dann Pamela , Yu Herbert , Fiaschi-Taesch Nathalie , Chang Wenhan , Wysolmerski John
Published: April 2023

supplemental materials and methods
Supplementary Table 1 from NFAT1 Directly Regulates IL8 and MMP3 to Promote Melanoma Tumor Growth and Metastasis
Authors: Shoshan Einav , Braeuer Russell R. , Kamiya Takafumi , Mobley Aaron K. , Huang Li , Vasquez Mayra E. , Velazquez-Torres Guermarie , Chakravarti Nitin , Ivan Cristina , Prieto Victor , Villares Gabriel J. , Bar-Eli Menashe
Published: April 2023

Top potential genes downregulated after silencing NFAT1
supplemental figures from Calcium-Sensing Receptor Promotes Breast Cancer by Stimulating Intracrine Actions of Parathyroid Hormone–Related Protein
Authors: Kim Wonnam , Takyar Farzin M. , Swan Karena , Jeong Jaekwang , VanHouten Joshua , Sullivan Catherine , Dann Pamela , Yu Herbert , Fiaschi-Taesch Nathalie , Chang Wenhan , Wysolmerski John
Published: April 2023

Supplemental Figure 1. A&B) Whole mount preparations of mammary glands from 9-week-old virgin CaSR; Supplemental Figure 2. A) Representative immunoblot showing total cdk2 levels in BT474 cells {plus minus} NPS2143 or control, CaSRKD, and PTHrPKD BT474 cells at different calcium concentrations; Supplemental Figure 3. A) Representative TUNEL staining in control MDA-MB-231.1833 cells {plus minus} NPS2143, and CaSRKD and PTHrPKD MDA-MB-231.1833 cells at different calcium concentrations; Supplemental Figure 4. A) Representative immunoblot for AIF in cytoplasmic or nuclear extracts from cells cultured from control MMTV-PyMT tumors {plus minus} NPS2143 and exposed to 5mM extracellular calcium; Supplemental Figure 5. BrdU incorporation in CaSRKD (A) or PTHrPKD (B) MDA-MB-231.1833 cells {plus minus} 10nM or 100nM PTHrP.
supplemental figure legends from Calcium-Sensing Receptor Promotes Breast Cancer by Stimulating Intracrine Actions of Parathyroid Hormone–Related Protein
Authors: Kim Wonnam , Takyar Farzin M. , Swan Karena , Jeong Jaekwang , VanHouten Joshua , Sullivan Catherine , Dann Pamela , Yu Herbert , Fiaschi-Taesch Nathalie , Chang Wenhan , Wysolmerski John
Published: April 2023

supplemental figure legends
Supplementary Table S4 from Hemolytic E. coli Promotes Colonic Tumorigenesis in Females
Authors: Jin Ye , Tang Senwei , Li Weilin , Ng Siew Chien , Chan Michael W.Y. , Sung Joseph J.Y. , Yu Jun
Published: April 2023

Primers used in this study
Supplementary Materials and Methods and Supplementary Figures 1 through 5 from Acidosis Acts through HSP90 in a PHD/VHL-Independent Manner to Promote HIF Function and Stem Cell Maintenance in Glioma
Authors: Filatova Alina , Seidel Sascha , Böğürcü Nuray , Gräf Sabine , Garvalov Boyan K. , Acker Till
Published: April 2023

Supplementary Information including: Supplementary Materials and Methods Supplementary References Supplementary Figure S1: Expression of HIF and HIF target genes in cells exposed to varying O2, CO2 and glucose levels. Supplementary Figure S2: Acidosis enhances the CSC phenotype. Supplementary Figure S3: Silencing of HIF1/2 by siRNA. Supplementary Figure S4: HSP90 inactivation by a dominant negative form of HSP90 reduces HIF levels and inhibits tumor growth. Supplementary Figure S5: Loss of HSP90 increases survival and reduces intratumoral HIF levels.
Supplementary Materials and Methods from Hemolytic E. coli Promotes Colonic Tumorigenesis in Females
Authors: Jin Ye , Tang Senwei , Li Weilin , Ng Siew Chien , Chan Michael W.Y. , Sung Joseph J.Y. , Yu Jun
Published: April 2023

Supplementary Materials and Methods
Supplementary Figure S2 from Hemolytic E. coli Promotes Colonic Tumorigenesis in Females
Authors: Jin Ye , Tang Senwei , Li Weilin , Ng Siew Chien , Chan Michael W.Y. , Sung Joseph J.Y. , Yu Jun
Published: April 2023

Verification of computational E. coli typing based on fimH mutation patterns. (A) Estimation of the factorization rank r in nonnegative matrix factorization (NMF). NMF analysis using 4 as the factorization rank r revealed that fimH could be classified into four types. (B) Consensus sequence of each type of fimH. Consensus sequences were illustrated by WebLogo using stacks of symbols. The size of symbols indicates the relative frequency of each base at that position.
Supplementary Figure S1 from Hemolytic E. coli Promotes Colonic Tumorigenesis in Females
Authors: Jin Ye , Tang Senwei , Li Weilin , Ng Siew Chien , Chan Michael W.Y. , Sung Joseph J.Y. , Yu Jun
Published: April 2023

E. coli typing based on fimH mutation patterns of fecal E. coli isolates. (A) Cluster analysis of single-nucleotide polymorphisms (SNP) of 711 fimH sequences. At the bottom of the figure are point mutations and their positions relative to the start codon of fimH. Red color represents that the mutations occur; blue color represents that the mutations do not occur. The horizontal box indicates the mutation pattern of type1-fimH. The vertical box indicates SNPs that are specific to type1-fimH and absent from the other types of fimH. (B) Distribution of the four types of E. coli in different subject groups. Each column represents a subject; each row represents fimH types of randomly selected fecal E. coli isolates. Color scheme: purple, type 1; blue, type 2, orange, type 3, green, type 4. (C) Percentage of subjects positive with each type of E. coli in different subject groups. H, the healthy subjects serving as controls; AD, patients with adenoma; CRC, patients with colorectal cancer. ***P < 0.001.
CAN-15-1348R-Supplementary materials and methods from Injury-Driven Stiffening of the Dermis Expedites Skin Carcinoma Progression
Authors: Mittapalli Venugopal R. , Madl Josef , Löffek Stefanie , Kiritsi Dimitra , Kern Johannes S. , Römer Winfried , Nyström Alexander , Bruckner-Tuderman Leena
Published: April 2023

Supplementary Materials and Methods
CAN-15-1348R-Supplementary Figure-S5 from Injury-Driven Stiffening of the Dermis Expedites Skin Carcinoma Progression
Authors: Mittapalli Venugopal R. , Madl Josef , Löffek Stefanie , Kiritsi Dimitra , Kern Johannes S. , Römer Winfried , Nyström Alexander , Bruckner-Tuderman Leena
Published: April 2023

Bar graph and immunofluorescence stainings
CAN-15-1348R-Supplementary Figure-S4 from Injury-Driven Stiffening of the Dermis Expedites Skin Carcinoma Progression
Authors: Mittapalli Venugopal R. , Madl Josef , Löffek Stefanie , Kiritsi Dimitra , Kern Johannes S. , Römer Winfried , Nyström Alexander , Bruckner-Tuderman Leena
Published: April 2023

Immunofluorescence stainings
Supplementary Table S4 from Comprehensive Ex Vivo Transposon Mutagenesis Identifies Genes That Promote Growth Factor Independence and Leukemogenesis
Authors: Guo Yabin , Updegraff Barrett L. , Park Sunho , Durakoglugil Deniz , Cruz Victoria H. , Maddux Sarah , Hwang Tae Hyun , O'Donnell Kathryn A.
Published: April 2023

Quantitative real-time PCR primer sequences.
CAN-15-1348R-Supplementary Figure-S1 from Injury-Driven Stiffening of the Dermis Expedites Skin Carcinoma Progression
Authors: Mittapalli Venugopal R. , Madl Josef , Löffek Stefanie , Kiritsi Dimitra , Kern Johannes S. , Römer Winfried , Nyström Alexander , Bruckner-Tuderman Leena
Published: April 2023

Bar graph showing qPCR quantification
Supplementary Table S2 from Comprehensive Ex Vivo Transposon Mutagenesis Identifies Genes That Promote Growth Factor Independence and Leukemogenesis
Authors: Guo Yabin , Updegraff Barrett L. , Park Sunho , Durakoglugil Deniz , Cruz Victoria H. , Maddux Sarah , Hwang Tae Hyun , O'Donnell Kathryn A.
Published: April 2023

CIS gene orthologues that are altered in ALL.
Supplementary Table S1 from Comprehensive Ex Vivo Transposon Mutagenesis Identifies Genes That Promote Growth Factor Independence and Leukemogenesis
Authors: Guo Yabin , Updegraff Barrett L. , Park Sunho , Durakoglugil Deniz , Cruz Victoria H. , Maddux Sarah , Hwang Tae Hyun , O'Donnell Kathryn A.
Published: April 2023

CIS gene orthologues that are altered in AML.
Supplementary Figure S6 from Macrophage Infiltration and Alternative Activation during Wound Healing Promote MEK1-Induced Skin Carcinogenesis
Authors: Weber Christine , Telerman Stephanie B. , Reimer Andreas S. , Sequeira Ines , Liakath-Ali Kifayathullah , Arwert Esther N. , Watt Fiona M.
Published: April 2023

Keratinocyte proliferation in PU.1-YFPxInvEE (InvEE) and PU.1-YFPxWT (WT) skin.
Supplementary Figure 5 from miR-34a Silences c-SRC to Attenuate Tumor Growth in Triple-Negative Breast Cancer
Authors: Adams Brian D. , Wali Vikram B. , Cheng Christopher J. , Inukai Sachi , Booth Carmen J. , Agarwal Seema , Rimm David L. , Győrffy Balázs , Santarpia Libero , Pusztai Lajos , Saltzman W. Mark , Slack Frank J.
Published: April 2023

Figure S5, Related to Figure 6. A, Assessment of SRC mRNA levels in MDA-MB-231 SRC-ORF, EMPTY-ORF, or parental cell lines. Data is normalized in RPL19 levels. B, Crystal violet staining assays on day 5 post-transfection confirms the ability of c-SRC to rescue miR-34a-induced anti-tumor growth. C-D, Examples of Pearson correlation analysis indicating MDA-MB-231 cells were not similar to BT-549 and MDA-MB-436 cells, and therefore were not included in the initial K-Means clustering analysis (results shown in D). E, The fold knockdown by miR-34a as compared to the miR-Scr treatments of the indicated genes in Clusters 1-3 in both BT-549 and MDA-MB-436 cells using a 2-fold change cut-off. None of the genes in Cluster 4 were downregulated by miR-34a (data not shown). F, Schematic of the KEGG pathway (hsa04510: Focal Adhesion) with miR-34a downregulated genes highlighted in red. G-H, Represents further analysis of the miR-34a gene signature in breast cancer. G, Indicates correlation analyses of miR-34a target genes in TNBC patients from Metabric data. H, Confirmation of prognostic importance of mIR-34a gene signature using a PROGgeneV2 algorithm on the TCGA data set.
Supplementary Figure S10 from Mutational Landscape and Antiproliferative Functions of ELF Transcription Factors in Human Cancer
Authors: Ando Mizuo , Kawazu Masahito , Ueno Toshihide , Koinuma Daizo , Ando Koji , Koya Junji , Kataoka Keisuke , Yasuda Takahiko , Yamaguchi Hiroyuki , Fukumura Kazutaka , Yamato Azusa , Soda Manabu , Sai Eirin , Yamashita Yoshihiro , Asakage Takahiro , Miyazaki Yasushi , Kurokawa Mineo , Miyazono Kohei , Nimer Stephen D. , Yamasoba Tatsuya , Mano Hiroyuki
Published: April 2023

Confirmation of ChIP-seq data for ELF4 binding sites by PCR analysis.
Supplementary Figure S1 from Mutational Landscape and Antiproliferative Functions of ELF Transcription Factors in Human Cancer
Authors: Ando Mizuo , Kawazu Masahito , Ueno Toshihide , Koinuma Daizo , Ando Koji , Koya Junji , Kataoka Keisuke , Yasuda Takahiko , Yamaguchi Hiroyuki , Fukumura Kazutaka , Yamato Azusa , Soda Manabu , Sai Eirin , Yamashita Yoshihiro , Asakage Takahiro , Miyazaki Yasushi , Kurokawa Mineo , Miyazono Kohei , Nimer Stephen D. , Yamasoba Tatsuya , Mano Hiroyuki
Published: April 2023

Expression level of ELF4 in trasient transfection assays
Supplementary Figure S1 from STAT3/IRF1 Pathway Activation Sensitizes Cervical Cancer Cells to Chemotherapeutic Drugs
Authors: Walch-Rückheim Barbara , Pahne-Zeppenfeld Jennifer , Fischbach Jil , Wickenhauser Claudia , Horn Lars Christian , Tharun Lars , Büttner Reinhard , Mallmann Peter , Stern Peter , Kim Yoo-Jin , Bohle Rainer Maria , Rübe Christian , Ströder Russalina , Juhasz-Böss Ingolf , Solomayer Erich-Franz , Smola Sigrun
Published: April 2023

79 human FFPE SCC were stained with anti-pTyr705-STAT3 Ab.
Supplementary Table S4 from HBXIP and LSD1 Scaffolded by lncRNA Hotair Mediate Transcriptional Activation by c-Myc
Authors: Li Yinghui , Wang Zhen , Shi Hui , Li Hang , Li Leilei , Fang Runping , Cai Xiaoli , Liu Bowen , Zhang Xiaodong , Ye Lihong
Published: April 2023

The common target genes of HBXIP and c-Myc.
Supplementary Table S3 from HBXIP and LSD1 Scaffolded by lncRNA Hotair Mediate Transcriptional Activation by c-Myc
Authors: Li Yinghui , Wang Zhen , Shi Hui , Li Hang , Li Leilei , Fang Runping , Cai Xiaoli , Liu Bowen , Zhang Xiaodong , Ye Lihong
Published: April 2023

The antibodies used in this study.
Supplementary Materials and Methods, Supplementary Figures 1 through 8, and Supplementary Tables 1 through 6 from Recurrent MLK4 Loss-of-Function Mutations Suppress JNK Signaling to Promote Colon Tumorigenesis
Authors: Marusiak Anna A. , Stephenson Natalie L. , Baik Hayeon , Trotter Eleanor W. , Li Yaoyong , Blyth Karen , Mason Susan , Chapman Phil , Puto Lorena A. , Read Jon A. , Brassington Claire , Pollard Hannah K. , Phillips Chris , Green Isabelle , Overman Ross , Collier Matthew , Testoni Ewelina , Miller Crispin J. , Hunter Tony , Sansom Owen J. , Brognard John
Published: April 2023

Supplementary methods. Figure S1. (related to Fig. 1A-F) Analysis of mutations of MLK4 and MLK1 present in CRC cells. Figure S2 (related to Fig. 2 and 3) Structural analysis of MLK4 mutants. Figure S3 (related to Fig. 2 and 3) Structural analysis of the effects of movements in the glycine rich motif. Figure S4 (related to Fig. 2 and 3) Structural changes within the C-spine and R-spine of MLK4 following loss-of-function mutations. Figure S5 (related to Fig. 4) Reintroduction of MLK4-WT decreases cell viability in LoVo cell line. Figure S6 (related to Fig. 4 and 6) Expression of MLK4 LOF mutants in CRC cells shows no phenotypic effects. Figure S7 (related to Fig. 4 and 6) Expression of MLK4-WT mutants in HCT116 cells shows no phenotypic effects. Figure S8 (related to Fig. 6) Associations between colon cancer patients with MLK4 mutations and expression levels of Cdk inhibitors. Table S1 (related to Fig. 1E) Characteristics of HCT15 and HT115 cell lines. Table S2 (related to Fig. 6A) Differential expression of genes in HCT15 reconstituted with MLK4-WT. Table S3 (related to Fig. 6A) Differential expression of genes in HT115 reconstituted with MLK4-WT. Table S4 (related to Fig. S7F) Differential expression of genes in HCT15 reconstituted with MLK4-Y330H. Table S5 (related to Fig. S7G) Differential expression of genes in HT115 reconstituted with MLK4-E314K. Table S6 (related to Fig. 1F) Crystal and refinement data.
Supplementary materials and methods from Neuropilin-2 Regulates Endosome Maturation and EGFR Trafficking to Support Cancer Cell Pathobiology
Authors: Dutta Samikshan , Roy Sohini , Polavaram Navatha S. , Stanton Marissa J. , Zhang Heyu , Bhola Tanvi , Hönscheid Pia , Donohue Terrence M. , Band Hamid , Batra Surinder K. , Muders Michael H. , Datta Kaustubh
Published: April 2023

Supplementary materials and methods
Supplementary Fig 4 from Neuropilin-2 Regulates Endosome Maturation and EGFR Trafficking to Support Cancer Cell Pathobiology
Authors: Dutta Samikshan , Roy Sohini , Polavaram Navatha S. , Stanton Marissa J. , Zhang Heyu , Bhola Tanvi , Hönscheid Pia , Donohue Terrence M. , Band Hamid , Batra Surinder K. , Muders Michael H. , Datta Kaustubh
Published: April 2023

Analysis of early and late endosomal proteins
Supplementary Fig 1 from Neuropilin-2 Regulates Endosome Maturation and EGFR Trafficking to Support Cancer Cell Pathobiology
Authors: Dutta Samikshan , Roy Sohini , Polavaram Navatha S. , Stanton Marissa J. , Zhang Heyu , Bhola Tanvi , Hönscheid Pia , Donohue Terrence M. , Band Hamid , Batra Surinder K. , Muders Michael H. , Datta Kaustubh
Published: April 2023

The depletion of NRP2 inhibits Rab switch that lead to an accumulation of immature autophagosome and early endosome
Supplemental figures from Multinucleation and Mesenchymal-to-Epithelial Transition Alleviate Resistance to Combined Cabazitaxel and Antiandrogen Therapy in Advanced Prostate Cancer
Authors: Martin Sarah K. , Pu Hong , Penticuff Justin C. , Cao Zheng , Horbinski Craig , Kyprianou Natasha
Published: April 2023

Supplemental Figures 1-7. Supplemental Figure 1: This figure shows the results of the dose response of human prostate cancer lines to antiandrogen (Enzalutamide) and Docetaxel (1st line taxane chemotherapy) as single agents and in combination treatment. It also describes the effect of AR variants on prostate cancer cell migration. Supplemental Figure 2: This figures describes the findings on the combined effect of Cabazitaxel ( 2nd line taxane chemotherapy) and Enzalutamie (antiandrogen) on AR expression, cellular localization and transcriptional activity ( target gene expression) in androgen-sensitive prostate cancer cells, VCaP. Supplemental Figure 3: This figure shows the results from confocal microscopy analysis on the cellular localization of AR variants, tubulin expression and nuclear presence in Cabazitaxel-resistant prostate cancer cells. Supplemental Figure 4: This Figure indicates the effect of Cabazitaxel treatment on kinesin protein and mRNA expression in androgen-responsive prostate cancer cells VCaP. Supplemental Figure 5: This Figure shows the results from immunofluorescence for detection of centrosomal amplification (pericentrin) in CRPC 22Rv1 cells after Cabazitaxel and antiandrogen treatment. Supplemental Figure 6: This Figure schematically summarizes the therapeutic regimen/dosing for in vivo treatment of pre-clinical transgenic model of prostate cancer with Cabazitaxel and antiandrogens and the consequences of treatment on body weight. Supplementary Figure 7: This Figure schematically describes the therapeutic dosing regimen of Cabazitaxel treatment in prostate cancer human xenograft model (22Rv1 castration resistant prostate cancer) in vivo. It also provides information on the antitumor effect of treatment on tumor growth and body weight of mice.
Supplementary Figure Legends from Peptide–Drug Conjugate GnRH–Sunitinib Targets Angiogenesis Selectively at the Site of Action to Inhibit Tumor Growth
Authors: Argyros Orestis , Karampelas Theodoros , Asvos Xenophon , Varela Aimilia , Sayyad Nisar , Papakyriakou Athanasios , Davos Constantinos H. , Tzakos Andreas G. , Fokas Demosthenes , Tamvakopoulos Constantin
Published: April 2023

Supplementary figure legends for supplementary figures 1-6
Supplemental Figure 3 from Dietary Microbes Modulate Transgenerational Cancer Risk
Authors: Poutahidis Theofilos , Varian Bernard J. , Levkovich Tatiana , Lakritz Jessica R. , Mirabal Sheyla , Kwok Caitlin , Ibrahim Yassin M. , Kearney Sean M. , Chatzigiagkos Antonis , Alm Eric J. , Erdman Susan E.
Published: April 2023

L. reuteri dietary enrichment protects the F1 progeny of NWD-fed mothers from transgenerational cancer. Pulmonary adenocarcinoma, hepatocellular carcinoma and mesenteric lymph node lymphoma in the children of mothers consuming NWD are shown in the left column. Compare with normal lung, liver and mesenteric lymph node histology from mice of similar descend that were also treated with L. reuteri.
Supplementary Materials and Methods, Legends for Supplementary Figures from Decreased Expression of Fructose-1,6-bisphosphatase Associates with Glucose Metabolism and Tumor Progression in Hepatocellular Carcinoma
Authors: Hirata Hidenari , Sugimachi Keishi , Komatsu Hisateru , Ueda Masami , Masuda Takaaki , Uchi Ryutaro , Sakimura Shotaro , Nambara Sho , Saito Tomoko , Shinden Yoshiaki , Iguchi Tomohiro , Eguchi Hidetoshi , Ito Shuhei , Terashima Kotaro , Sakamoto Katsumi , Hirakawa Masakazu , Honda Hiroshi , Mimori Koshi
Published: April 2023

Supplementary Materials and Methods, and Legends for Supplementary Figures.
Supplemental Table S3 from JARID1D Is a Suppressor and Prognostic Marker of Prostate Cancer Invasion and Metastasis
Authors: Li Na , Dhar Shilpa S. , Chen Tsai-Yu , Kan Pu-Yeh , Wei Yongkun , Kim Jae-Hwan , Chan Chia-Hsin , Lin Hui-Kuan , Hung Mien-Chie , Lee Min Gyu
Published: April 2023

Top 150 genes up-regulated by JARID1D knockdown in DU145 cells.
Supplementary Figure S3 from Decreased Expression of Fructose-1,6-bisphosphatase Associates with Glucose Metabolism and Tumor Progression in Hepatocellular Carcinoma
Authors: Hirata Hidenari , Sugimachi Keishi , Komatsu Hisateru , Ueda Masami , Masuda Takaaki , Uchi Ryutaro , Sakimura Shotaro , Nambara Sho , Saito Tomoko , Shinden Yoshiaki , Iguchi Tomohiro , Eguchi Hidetoshi , Ito Shuhei , Terashima Kotaro , Sakamoto Katsumi , Hirakawa Masakazu , Honda Hiroshi , Mimori Koshi
Published: April 2023

The expression levels of genes specific to gluconeogenesis in HCC cases.
Supplementary Figure S1 from Decreased Expression of Fructose-1,6-bisphosphatase Associates with Glucose Metabolism and Tumor Progression in Hepatocellular Carcinoma
Authors: Hirata Hidenari , Sugimachi Keishi , Komatsu Hisateru , Ueda Masami , Masuda Takaaki , Uchi Ryutaro , Sakimura Shotaro , Nambara Sho , Saito Tomoko , Shinden Yoshiaki , Iguchi Tomohiro , Eguchi Hidetoshi , Ito Shuhei , Terashima Kotaro , Sakamoto Katsumi , Hirakawa Masakazu , Honda Hiroshi , Mimori Koshi
Published: April 2023

Isotopomer distribution analysis using [U-13C]glucose in HuH7 cells with or without ectopic FBP1 expression.
Table S2 from Non–Small Cell Lung Cancer Cells Acquire Resistance to the ALK Inhibitor Alectinib by Activating Alternative Receptor Tyrosine Kinases
Authors: Isozaki Hideko , Ichihara Eiki , Takigawa Nagio , Ohashi Kadoaki , Ochi Nobuaki , Yasugi Masayuki , Ninomiya Takashi , Yamane Hiromichi , Hotta Katsuyuki , Sakai Katsuya , Matsumoto Kunio , Hosokawa Shinobu , Bessho Akihiro , Sendo Toshiaki , Tanimoto Mitsune , Kiura Katsuyuki
Published: April 2023

Probe and primer
Suppl. Figure 4 from Non–Small Cell Lung Cancer Cells Acquire Resistance to the ALK Inhibitor Alectinib by Activating Alternative Receptor Tyrosine Kinases
Authors: Isozaki Hideko , Ichihara Eiki , Takigawa Nagio , Ohashi Kadoaki , Ochi Nobuaki , Yasugi Masayuki , Ninomiya Takashi , Yamane Hiromichi , Hotta Katsuyuki , Sakai Katsuya , Matsumoto Kunio , Hosokawa Shinobu , Bessho Akihiro , Sendo Toshiaki , Tanimoto Mitsune , Kiura Katsuyuki
Published: April 2023

Characteristics of the ABC-11/CHR and ABC-11/CHR clones
Suppl. Figure 3 from Non–Small Cell Lung Cancer Cells Acquire Resistance to the ALK Inhibitor Alectinib by Activating Alternative Receptor Tyrosine Kinases
Authors: Isozaki Hideko , Ichihara Eiki , Takigawa Nagio , Ohashi Kadoaki , Ochi Nobuaki , Yasugi Masayuki , Ninomiya Takashi , Yamane Hiromichi , Hotta Katsuyuki , Sakai Katsuya , Matsumoto Kunio , Hosokawa Shinobu , Bessho Akihiro , Sendo Toshiaki , Tanimoto Mitsune , Kiura Katsuyuki
Published: April 2023

Characteristics of the H2228 and H2228/CHR clones
Supplementary Table 1, Supplementary Figures 1 through 9, and Supplementary Materials and Methods from Radiation-Induced Loss of Salivary Gland Function Is Driven by Cellular Senescence and Prevented by IL6 Modulation
Authors: Marmary Yitzhak , Adar Revital , Gaska Svetlana , Wygoda Annette , Maly Alexander , Cohen Jonathan , Eliashar Ron , Mizrachi Lina , Orfaig-Geva Carmit , Baum Bruce J. , Rose-John Stefan , Galun Eithan , Axelrod Jonathan H.
Published: April 2023

Supplementary Table S1 - Patient Characteristics Supplementary Fig. S1 - IR-induced morphology and inflammatory responses Supplementary Fig. S2 - Apoptosis following IR Supplementary Fig. S3 - Morphology, Aquaporin and ??H2AX in Acini following IR Supplementary Fig. S4 - IL-6 is crucial for persistence of DDR Supplementary Fig. S5 - IL-6 infusion induces IL-6 upregulation. Supplementary Fig. S6 - IL-6 and HIL-6 pretreatment reduces persistent DDR Supplementary Fig. S7 - IL-6 pretreatment accelerates DNA damage repair Supplementary Fig. S8 - IL-6 deficiency does not affect DDR Supplementary Fig. S9 - HIL-6 pretreatment does not affect distal tumor radiotherapy Supplementary Figure Legends Supplementary Materials and Methods
Supplementary Table S2 from Hypoxia-Induced Epithelial-to-Mesenchymal Transition in Hepatocellular Carcinoma Induces an Immunosuppressive Tumor Microenvironment to Promote Metastasis
Authors: Ye Long-Yun , Chen Wei , Bai Xue-Li , Xu Xing-Yuan , Zhang Qi , Xia Xue-Feng , Sun Xu , Li Guo-Gang , Hu Qi-Da , Fu Qi-Han , Liang Ting-Bo
Published: April 2023

Univariate and multivariate analysis of factors associated with survival in HCC patients.
Supplemental Material from Decoding Intratumoral Heterogeneity of Breast Cancer by Multiparametric In Vivo Imaging: A Translational Study
Authors: Schmitz Jennifer , Schwab Julian , Schwenck Johannes , Chen Qian , Quintanilla-Martinez Leticia , Hahn Markus , Wietek Beate , Schwenzer Nina , Staebler Annette , Kohlhofer Ursula , Aina Olulanu H. , Hubbard Neil E. , Reischl Gerald , Borowsky Alexander D. , Brucker Sara , Nikolaou Konstantin , la Fougère Christian , Cardiff Robert D. , Pichler Bernd J. , Schmid Andreas M.
Published: April 2023

More detailed description of ex-vivo procedures of mouse tumor samples
Supplementary Figure S6 from Hypoxia-Induced Epithelial-to-Mesenchymal Transition in Hepatocellular Carcinoma Induces an Immunosuppressive Tumor Microenvironment to Promote Metastasis
Authors: Ye Long-Yun , Chen Wei , Bai Xue-Li , Xu Xing-Yuan , Zhang Qi , Xia Xue-Feng , Sun Xu , Li Guo-Gang , Hu Qi-Da , Fu Qi-Han , Liang Ting-Bo
Published: April 2023

Representative images of the different pathological scores for CCL20 and HIF-1α used in our scoring system for HCC.
Supplemental Figure Legend from Decoding Intratumoral Heterogeneity of Breast Cancer by Multiparametric In Vivo Imaging: A Translational Study
Authors: Schmitz Jennifer , Schwab Julian , Schwenck Johannes , Chen Qian , Quintanilla-Martinez Leticia , Hahn Markus , Wietek Beate , Schwenzer Nina , Staebler Annette , Kohlhofer Ursula , Aina Olulanu H. , Hubbard Neil E. , Reischl Gerald , Borowsky Alexander D. , Brucker Sara , Nikolaou Konstantin , la Fougère Christian , Cardiff Robert D. , Pichler Bernd J. , Schmid Andreas M.
Published: April 2023

Detailed description of mean and max value analysis of ADC and [18F]FDG data of tumors of tg(PyV-mT) mice.
Supplementary Figure S5 from Hypoxia-Induced Epithelial-to-Mesenchymal Transition in Hepatocellular Carcinoma Induces an Immunosuppressive Tumor Microenvironment to Promote Metastasis
Authors: Ye Long-Yun , Chen Wei , Bai Xue-Li , Xu Xing-Yuan , Zhang Qi , Xia Xue-Feng , Sun Xu , Li Guo-Gang , Hu Qi-Da , Fu Qi-Han , Liang Ting-Bo
Published: April 2023

CCL20 expression is not associated with IDO expression in the normal liver and tumor without PVTT groups.
Supplementary Figures 1-10 from Cdx2 Expression and Intestinal Metaplasia Induced by H. pylori Infection of Gastric Cells Is Regulated by NOD1-Mediated Innate Immune Responses
Authors: Asano Naoki , Imatani Akira , Watanabe Tomohiro , Fushiya Jun , Kondo Yutaka , Jin Xiaoyi , Ara Nobuyuki , Uno Kaname , Iijima Katsunori , Koike Tomoyuki , Strober Warren , Shimosegawa Tooru
Published: April 2023

Supplementary Figure 1. Cdx2 expression in human gastric epithelial cell lines. Supplementary Figure 2. The expression of Cdx2 was enhanced by H. pylori infection in gastric epithelial cell. Supplementary Figure 3. Scheme of the Cdx2 prmoter-luciferase reporter plasmids used in this study. Supplementary Figure 4. BAY11-7082 inhibits NF-κB activation. Supplementary Figure 5. NOD1 siRNA reduced the expression of NOD1. Supplementary Figure 6. Cdx2 and MUC2 expression in GSM06 cells. Supplementary Figure 7. Pretreatment with iE-DAP reduces H. pylori infection-induced Cdx2 expression. Supplementary Figure 8. iE-DAP alone does not alter Cdx2 expression. Supplementary Figure 9. Inflammatory scores of the stomach did not differ between NOD1-intact and NOD1-deficient mice. Supplementary Figure 10. TNF-α was induced in the stomachs of H. pylori-infected mice.
Supplementary Materials and Methods from Formation of Renal Cysts and Tumors in Vhl/Trp53-Deficient Mice Requires HIF1α and HIF2α
Authors: Schönenberger Désirée , Harlander Sabine , Rajski Michal , Jacobs Robert A. , Lundby Anne-Kristine , Adlesic Mojca , Hejhal Tomas , Wild Peter J. , Lundby Carsten , Frew Ian J.
Published: April 2023

Additional information related to antibodies, oligonucleotides, metabolic assays and respirometry.
Supplemental Figure Legends from Molecular Pathology of Patient Tumors, Patient-Derived Xenografts, and Cancer Cell Lines
Authors: Guo Sheng , Qian Wubin , Cai Jie , Zhang Likun , Wery Jean-Pierre , Li Qi-Xiang
Published: April 2023

Supplemental Figure Legends
Figure S3 from Molecular Pathology of Patient Tumors, Patient-Derived Xenografts, and Cancer Cell Lines
Authors: Guo Sheng , Qian Wubin , Cai Jie , Zhang Likun , Wery Jean-Pierre , Li Qi-Xiang
Published: April 2023

Figure S3. Immunohistochemistry (IHC) staining for confirmation of tumor types.
Supplementary Figure S8 from Oncogenic Mutation of AIMP2/p38 Inhibits Its Tumor-Suppressive Interaction with Smurf2
Authors: Kim Dae Gyu , Lee Jin Young , Lee Ji-Hyun , Cho Ha Yeon , Kang Beom Sik , Jang Song-Yee , Kim Myung Hee , Guo Min , Han Jung Min , Kim Seong-Jin , Kim Sunghoon
Published: April 2023

Multiple sequence alignment of metazoan AIMP2.
Supplementary Figure S6 from Oncogenic Mutation of AIMP2/p38 Inhibits Its Tumor-Suppressive Interaction with Smurf2
Authors: Kim Dae Gyu , Lee Jin Young , Lee Ji-Hyun , Cho Ha Yeon , Kang Beom Sik , Jang Song-Yee , Kim Myung Hee , Guo Min , Han Jung Min , Kim Seong-Jin , Kim Sunghoon
Published: April 2023

Functional significance of TGF-β1-induced phosphorylation of AIMP2.
Supplementary Figure S7 from MIF Maintains the Tumorigenic Capacity of Brain Tumor–Initiating Cells by Directly Inhibiting p53
Authors: Fukaya Raita , Ohta Shigeki , Yaguchi Tomonori , Matsuzaki Yumi , Sugihara Eiji , Okano Hideyuki , Saya Hideyuki , Kawakami Yutaka , Kawase Takeshi , Yoshida Kazunari , Toda Masahiro
Published: April 2023

Schematic model of MIF function in two different types of glioma cells containing wild-type or mutant P53.
Supplemental Figure 5 from Nucleolin Promotes Heat Shock–Associated Translation of VEGF-D to Promote Tumor Lymphangiogenesis
Authors: Morfoisse Florent , Tatin Florence , Hantelys Fransky , Adoue Aurelien , Helfer Anne-Catherine , Cassant-Sourdy Stephanie , Pujol Françoise , Gomez-Brouchet Anne , Ligat Laetitia , Lopez Frederic , Pyronnet Stephane , Courty Jose , Guillermet-Guibert Julie , Marzi Stefano , Schneider Robert J. , Prats Anne-Catherine , Garmy-Susini Barbara H.
Published: April 2023

Figure S5. VEGF-D 5'UTR mRNA exhibits two structural forms that allow the binding of different proteins
Figure S5 from Nutritional Stress Induced by Tryptophan-Degrading Enzymes Results in ATF4-Dependent Reprogramming of the Amino Acid Transporter Profile in Tumor Cells
Authors: Timosenko Elina , Ghadbane Hemza , Silk Jonathan D. , Shepherd Dawn , Gileadi Uzi , Howson Lauren J. , Laynes Robert , Zhao Qi , Strausberg Robert L. , Olsen Lars R. , Taylor Stephen , Buffa Francesca M. , Boyd Richard , Cerundolo Vincenzo
Published: April 2023

Characterization of mTOR pathway activation, tryptophan transport and WARS expression in primary human T cells under activation/tryptophan deprivation conditions.
Figure S1 from Nutritional Stress Induced by Tryptophan-Degrading Enzymes Results in ATF4-Dependent Reprogramming of the Amino Acid Transporter Profile in Tumor Cells
Authors: Timosenko Elina , Ghadbane Hemza , Silk Jonathan D. , Shepherd Dawn , Gileadi Uzi , Howson Lauren J. , Laynes Robert , Zhao Qi , Strausberg Robert L. , Olsen Lars R. , Taylor Stephen , Buffa Francesca M. , Boyd Richard , Cerundolo Vincenzo
Published: April 2023

Tryptophan network MetaCore analysis and SLC1A5 isoform genomic organization.
Supplementary Table S2: from Cancer Therapy Directed by Comprehensive Genomic Profiling: A Single Center Study
Authors: Wheler Jennifer J. , Janku Filip , Naing Aung , Li Yali , Stephen Bettzy , Zinner Ralph , Subbiah Vivek , Fu Siqing , Karp Daniel , Falchook Gerald S. , Tsimberidou Apostolia M. , Piha-Paul Sarina , Anderson Roosevelt , Ke Danxia , Miller Vincent , Yelensky Roman , Lee J. Jack , Hong David S. , Kurzrock Razelle
Published: April 2023

Matched-direct versus matched-indirect therapy: Definitions of exploratory analyses based on targeta impact
Supplementary Figure S5 from The CARMA3–Bcl10–MALT1 Signalosome Drives NFκB Activation and Promotes Aggressiveness in Angiotensin II Receptor–Positive Breast Cancer
Authors: Ekambaram Prasanna , Lee Jia-Ying (Lloyd) , Hubel Nathaniel E. , Hu Dong , Yerneni Saigopalakrishna , Campbell Phil G. , Pollock Netanya , Klei Linda R. , Concel Vincent J. , Delekta Phillip C. , Chinnaiyan Arul M. , Tomlins Scott A. , Rhodes Daniel R. , Priedigkeit Nolan , Lee Adrian V. , Oesterreich Steffi , McAllister-Lucas Linda M. , Lucas Peter C.
Published: April 2023

Role of Bcl10 in mediating cell migration and invasion of additional AGTR1+ breast cancer cell lines (Hs578T and Hs606T).
Table S2 from Noninvasive In Vivo Imaging and Biologic Characterization of Thyroid Tumors by ImmunoPET Targeting of Galectin-3
Authors: D'Alessandria Calogero , Braesch-Andersen Sten , Bejo Kristel , Reder Sybille , Blechert Birgit , Schwaiger Markus , Bartolazzi Armando
Published: April 2023

Biodistribution analysis of 89Zr-labelled anti-Gal3 mAb in three different animal models.
Supplemental Figure Legends from Noninvasive In Vivo Imaging and Biologic Characterization of Thyroid Tumors by ImmunoPET Targeting of Galectin-3
Authors: D'Alessandria Calogero , Braesch-Andersen Sten , Bejo Kristel , Reder Sybille , Blechert Birgit , Schwaiger Markus , Bartolazzi Armando
Published: April 2023

Legends for Supplementary Figures S1-S2.