bluuebunny/crossref_metadata_2025 huggingface dataset:
Clinical, Immunological and Inflammatory Characteristics among Mexican Children with Different Subtypes of Juvenile Idiopathic Arthritis: Exploring the Correlation between Anti-Cyclic Citrullinated Peptide (anti-CCP) and Rheumatoid Factor (RF)
Authors: Hernández-Huirache Hayde Guadalupe , Armenta-Medina Dagoberto , Rodea-Montero Edel Rafael
Published: February 2024

Introduction: Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic disease in childhood, affecting one to four of every 1000 children worldwide. It is characterized by joint inflammation lasting more than six weeks in children under 16 years. The aim of this study was to estimate the frequency of JIA subtypes in the Mexican patient population; compare clinical, immunological and inflammation markers by JIA subtype; and examine the correlation between these variables. Methods: We conducted a cross-sectional study of 50 patients with JIA (2–15 years). We estimated the frequency of each JIA subtype, assessed and compared the immunological characteristics (RF, ANA and anti-CCP) by JIA subtype at the time of diagnosis using Kruskal–Wallis or chi-square tests, and calculated Spearman correlation coefficients between the assessments. Results: Our analysis included 50 patients, 29 (58%) girls and 21 (42%) boys, aged at the time of diagnosis 10.56  ±  3.99 years. The frequencies of JIA subtypes were RF-seropositive polyarthritis (34%), RF-seronegative polyarthritis (28%), systemic arthritis (16%), oligoarthritis (14%) and arthritis-related enthesitis (8%). We found a significant association between sex and JIA subtype (p = 0.014). There was a significant difference in anti-CCP levels by JIA subtype (p < 0.001). We also detected positive correlations between RF and anti-CCP (r = 0.63, p < 0.001) and between age and anti-CCP (r = 0.29, p = 0.041). Conclusions: Our study suggests that the frequency of the polyarticular subtypes of JIA is higher in Mexican children compared to other populations. Our findings highlight the importance of considering the presence of anti-CCP and RF as important criteria when deciding on treatment for JIA patients as elevated levels of these antibodies may indicate early forms of adult rheumatoid arthritis.
Efficient Third Harmonic Generation from Magnetic Resonance in Low-Index Dielectric Nanopillars
Authors: Xie Rui , He Xiaobo , Wang Wenqiang , Zheng Liren , Shi Junjun
Published: February 2024

Boosting the harmonic generation of light in nanostructures through efficiently enhancing the light–matter interaction has received enormous attention and applications. Low-index dielectric nanoparticles, as one of the crucial members of nanophotonics, have not been successful in nonlinear enhancement due to weak Mie resonance and poor light confinement. Here, we designed efficient third harmonic generation (THG) in low-index dielectric nanopillars sandwiched by double layers of metal dressing (Au/polymer/Au), where the polymer offers essential nonlinear susceptibility. The resonance of the low-index nanopillars significantly enhanced the scattering and had a strong magnetic response that could boost the THG effect. We predict that the THG efficiency reaches up to 3 × 10−6 (six orders of enhancement) at a third harmonic wavelength of 300 nm. The efficient THG in low-index dielectric nanopillars may open the possibility for the development of a new type of efficient nonlinear coherent source.
Experimental Study on Partially Coherent Optical Coherent Detection
Authors: Liang Jingyuan , Mu Yi , Ke Xizheng , Han Meimiao
Published: February 2024

When coherent detection occurs, the polarization mismatch between signal light and local oscillator light can reduce the efficiency of coherent detection. This article combines the principle of optical mixers to derive the relationship between the polarization state and mixing efficiency of signal light and local oscillator light, and builds an experimental platform for the coherent detection of a partially coherent electromagnetic Gaussian Schell beam (EGSM). Polarization devices are used to regulate the polarization state of the signal EGSM light and local oscillator EGSM light, and different polarization states of the EGSM beams are generated. When the output power of the signal light is constant, the mixing efficiency is measured according to the output amplitude of the intermediate frequency signal. This experiment found that when the signal light is in a linearly polarized state and the local oscillator light is in a linearly polarized state, a circularly polarized state, or an elliptically polarized state, the amplitude of the intermediate frequency signal is 369.6 mv, 146.6 mv, or 92.1 mv, respectively. When the signal light is in a circularly polarized state, the amplitude of the intermediate frequency signal is 446.4 mv, 504.0 mv, or 159.2 mv, respectively. When the signal light is in an elliptical polarization state, the amplitude of the intermediate frequency signal is 94.4 mv, 124.0 mv, or 254.8 mv, respectively.
The Cooperation Regulation of Antioxidative System and Hormone Contents on Physiological Responses of Wedelia trilobata and Wedelia chinensis under Simulated Drought Environment
Authors: Huang Ping , Xu Zhiwei , He Weijie , Yang Hong , Li Bin , Ding Wendian , Lei Yuze , Abbas Adeel , Hameed Rashida , Wang Congyan , Sun Jianfan , Du Daolin
Published: February 2024

Drought-induced metabolic dysregulation significantly enhances the production of reactive oxygen species (ROS), which, in turn, exerts a substantial influence on the oxidation–reduction regulatory status of cells. These ROS, under conditions of drought stress, become highly reactive entities capable of targeting various plant organelles, metabolites, and molecules. Consequently, disruption affects a wide array of metabolic pathways and eventually leads to the demise of the cells. Given this understanding, this study aimed to investigate the effects of different drought stress levels on the growth and development of the invasive weed Wedelia trilobata and its co-responding native counterpart Wedelia chinensis. Both plants evolved their defense mechanisms to increase their antioxidants and hormone contents to detoxify ROS to avoid oxidative damage. Still, the chlorophyll content fluctuated and increased in a polyethylene-glycol-simulated drought. The proline content also rose in the plants, but W. chinensis showed a significant negative correlation between proline and malondialdehyde in different plant parts. Thus, W. trilobata and W. chinensis exhibited diverse or unlike endogenous hormone regulation patterns under drought conditions. Meanwhile, W. trilobata and W. chinensis pointedly increased the content of indole acetic acid and gibberellic acid in a different drought stress environment. A positive correlation was found between endogenous hormones in other plant parts, including in the roots and leaves. Both simulated and natural drought conditions exerted a significant influence on both plant species, with W. trilobata displaying superior adaptation characterized by enhanced growth, bolstered antioxidant defense mechanisms, and heightened hormonal activities.
Hydrogen Peroxide Promotes Tomato Leaf Senescence by Regulating Antioxidant System and Hydrogen Sulfide Metabolism
Authors: Yu Yue , Wang Siyue , Guo Wentong , Geng Meihui , Sun Ying , Li Wanjie , Yao Gaifang , Zhang Danfeng , Zhang Hua , Hu Kangdi
Published: February 2024

Hydrogen peroxide (H2O2) is relatively stable among ROS (reactive oxygen species) and could act as a signal in plant cells. In the present work, detached tomato leaves were treated with exogenous H2O2 at 10 mmol/L for 8 h to study the mechanism of how H2O2 regulates leaf senescence. The data indicated that H2O2 treatment significantly accelerated the degradation of chlorophyll and led to the upregulation of the expression of leaf senescence-related genes (NYC1, PAO, PPH, SGR1, SAG12 and SAG15) during leaf senescence. H2O2 treatment also induced the accumulation of H2O2 and malondialdehyde (MDA), decreased POD and SOD enzyme activities and inhibited H2S production by reducing the expression of LCD1/2 and DCD1/2. A correlation analysis indicated that H2O2 was significantly and negatively correlated with chlorophyll, the expression of leaf senescence−related genes, and LCD1/2 and DCD1/2. The principal component analysis (PCA) results show that H2S showed the highest load value followed by O2•−, H2O2, DCD1, SAG15, etc. Therefore, these findings provide a basis for studying the role of H2O2 in regulating detached tomato leaf senescence and demonstrated that H2O2 plays a positive role in the senescence of detached leaves by repressing antioxidant enzymes and H2S production.
Difference in Germination Traits between Congeneric Native and Exotic Species May Affect Invasion
Authors: Salomé-Díaz Julieta , Golubov Jordan , Eguiarte Luis E. , Búrquez Alberto
Published: February 2024

Germination traits are components of invasion potential, and comparing seed traits in sympatric native and invasive species can offer insights into the invasion process. We characterized seed germination traits and how they influenced the success of Eragrostis mexicana, a native species, and Eragrostis tenuifolia, an exotic species (Poaceae) in Mexico, in the context of their potential for biological invasion. Seeds from both species were collected from four sites in a natural protected area in Mexico City, and the germination of seeds of different ages was conducted in experiments at different temperatures. E. tenuifolia exhibited higher germination percentages than the native E. mexicana across all treatments. Seed age had differential effects, with older seeds of the native E. mexicana germinating better, while E. tenuifolia performed better with younger seeds. Temperature positively impacted germination for both species, although E. mexicana was limited at lower temperatures. Exotic E. tenuifolia can germinate over a wider temperature range with earlier germination rates, and generate a seed bank lasting several years, which may contribute to naturalization. The importance of germination traits in the context of invasive species establishment underscores the potential role of seed banks in facilitating biological invasions.
Enhancing Chitosan Fibers: A Dual Approach with Tripolyphosphate and Ursolic Acid
Authors: Hernández Vázquez César , Draczyński Zbigniew , Borkowski Dominik , Kaźmierczak Dorota
Published: February 2024

Chitosan, a well-established biomaterial known for its biocompatibility, biodegradability, and bioactivity, has been the focus of extensive research in recent years. This study explores the enhancement of chitosan fibers’ properties through wet impregnation with either ursolic acid (UA) or cross-linking with tripolyphosphate (TPP). In the first experiment, chitosan fibers were treated with UA, for varying immersion set points (1, 2, 4, 6, and 8 h). FTIR, SEM, and UV-Vis spectroscopy analyses demonstrated a chemical reaction between chitosan and UA, with stability reached after 2 h of immersion. Antibacterial testing revealed that chitosan fibers impregnated with UA exhibited significant antibacterial activity against Gram-positive bacteria, notably Staphylococcus aureus. The second experiment involved modifying chitosan fibers’ surfaces with a 1% w/v TPP solution for the same periods of time (1, 2, 4, 6, and 8 h). Subsequently, the investigation involved FTIR, SEM, and dynamometry analyses, which revealed successful cross-linking between chitosan and TPP ions, resulting in improved tensile strength after 2 h of immersion. This dual-approach study highlights the potential of chitosan fibers for diverse applications, from wound-healing dressings to antibacterial materials against Gram-positive bacteria.
Preparation and Properties of Gel Polymer Electrolytes with Li1.5Al0.5Ge1.5(PO4)3 and Li6.46La3Zr1.46Ta0.54O12 by UV Curing Process
Authors: Liang Xinghua , Hun Qiankun , Lan Lingxiao , Zhang Bing , Chen Zhikun , Wang Yujiang
Published: February 2024

Poly (vinylidene fluoride-co-hexafluoropropylene) (PVDF-HFP)-based gel polymer electrolytes (GPEs) are considered a promising electrolyte candidate for polymer lithium-ion batteries (LIBs) because of their free-standing shape, versatility, security, flexibility, lightweight, reliability, and so on. However, due to problems such as low ionic conductivity, PVDF-HFP can only be used on a small scale when used as a substrate alone. To overcome the above shortcomings, GPEs were designed and synthesized by a UV curing process by adding NASICON-type Li1.5Al0.5Ge1.5(PO4)3 (LAGP) and garnet-type Li6.46La3Zr1.46Ta0.54O12 (LLZTO) to PVDF-HFP. Experimentally, GPEs with 10% weight LLZTO in a PVDF-HFP matrix had an ionic conductivity of up to 3 × 10−4 S cm−1 at 25 °C. When assembled into LiFePO4/GPEs/Li batteries, a discharge-specific capacity of 81.5 mAh g−1 at a current density of 1 C and a capacity retention rate of 98.1% after 100 cycles at a current density of 0.2 C occurred. Therefore, GPEs added to LLZTO have a broad application prospect regarding rechargeable lithium-ion batteries.
Effects of Synthesis Parameters on Structure and Antimicrobial Properties of Bacterial Cellulose/Hydroxyapatite/TiO2 Polymer–Ceramic Composite Material
Authors: Sknepnek Aleksandra , Filipović Suzana , Pavlović Vladimir B. , Mirković Nemanja , Miletić Dunja , Gržetić Jelena , Mirković Miljana
Published: February 2024

Bacterial cellulose (BC) is a highly pure polysaccharide biopolymer that can be produced by various bacterial genera. Even though BC lacks functional properties, its porosity, three-dimensional network, and high specific surface area make it a suitable carrier for functional composite materials. In the present study, BC-producing bacteria were isolated from kombucha beverage and identified using a molecular method. Two sets of the BC hydrogels were produced in static conditions after four and seven days. Afterwards, two different synthesis pathways were applied for BC functionalization. The first method implied the incorporation of previously synthesized HAp/TiO2 nanocomposite using an immersion technique, while the second method included the functionalization of BC during the synthesis of HAp/TiO2 nanocomposite in the reaction mixture. The primary goal was to find the best method to obtain the functionalized material. Physicochemical and microstructural properties were analyzed by SEM, EDS, FTIR, and XRD methods. Further properties were examined by tensile test and thermogravimetric analysis, and antimicrobial activity was assessed by a total plate count assay. The results showed that HAp/TiO2 was successfully incorporated into the produced BC hydrogels using both methods. The applied methods of incorporation influenced the differences in morphology, phase distribution, mechanical and thermal properties, and antimicrobial activity against Staphylococcus aureus (ATCC 25923), Escherichia coli (ATCC 25922), Proteus mirabilis (ATCC 12453), and Candida albicans (ATCC 10231). Composite material can be recommended for further development and application in environments that are suitable for diseases spreading.
Advancing PetroChina’s Development Strategies for Low-Permeability Oil Reservoirs
Authors: Cao Jun , Hao Mingqiang , Chen Yujia , Li Baozhu , Liu Zhuo , Liu Yang , Xu Jinze
Published: February 2024

Based on PetroChina’s status and situation of low-permeability oil reservoir development, this paper analyzes the key common issues in the production capacity construction of new oilfields, the stable production of old oilfields, and enhanced oil recovery, and, in connection with the progress made in major development technologies and the results of major development tests for low-permeability oil reservoirs in recent years, puts forward the technical countermeasures and development directions. For optimizing the development of low-grade reserves, a comprehensive life-cycle development plan is essential, alongside experimenting with gas injection and energy supplementation in new fields. Addressing challenges in reservoir classification, multidisciplinary sweet spot prediction, and displacement–imbibition processes can significantly boost well productivity. In fine water flooding reservoirs, the focus should shift to resolving key technological challenges like dynamic heterogeneity characterization, and functional and nano-intelligent water flooding. For EOR, accelerating the application of carbon capture, utilization, and storage (CCUS) advancements, along with air injection thermal miscible flooding, and middle-phase microemulsion flooding, is crucial. This approach aims to substantially enhance recovery and establish a new model of integrated secondary and tertiary recovery methods.
The IADC Grief Questionnaire as a Brief Measure for Complicated Grief in Clinical Practice and Research: A Preliminary Study
Authors: D’Antoni Fabio , Lalla Claudio
Published: February 2024

IADC (induced after-death communication) therapy is a grief treatment developed by Botkin that is increasingly being acknowledged for its effectiveness in various countries worldwide. In clinical practice, professionals trained in IADC therapy employ a brief evaluation tool called the IADC Grief Questionnaire (IADC-GQ) to determine whether mourning can be disturbed or stopped, resulting in complicated grief. This preliminary research aimed to establish the psychometric properties of the IADC-GQ. The factor structure was analyzed in a sample consisting of 113 participants undergoing psychological treatment who had endured the loss of a loved one for a minimum of six months. The findings revealed a two-dimensional framework comprising two distinct factors: the “Clinical Score”, encompassing the most distressing elements of grief, and the “Continuing Bond” factor, which is associated with feelings of connection to the departed and thoughts regarding the existence of life after death. The IADC-GQ has the potential to be easily and quickly employed in both research and clinical settings. Moreover, it can qualitatively assist therapists during clinical interviews by highlighting the key areas where the grieving process may encounter obstacles.
Neuropsychological Insights into Coping Strategies: Integrating Theory and Practice in Clinical and Therapeutic Contexts
Authors: Theodoratou Maria , Argyrides Marios
Published: February 2024

The primary focus of this review is to rigorously explore the application and significance of coping strategies within the domains of clinical psychology and neuropsychology. These consist of a variety of techniques, behaviors, and cognitive interventions, and their critical role in reinforcing resilience and facilitating adaptive responses to stressors has been highlighted. This study explores the complex neuropsychological links between the brain’s stress pathways and the use of coping mechanisms. The neural aspects of stress, and how they can be influenced by adaptive strategies, are detailed, illustrating the profound impact that these coping mechanisms have at a neurobiological level. Delving into the neuropsychological underpinnings, this review will shed light on how stress response pathways in the brain interact with, and can be modulated by, various coping strategies. These mechanisms are particularly salient when addressing the multifaceted challenges that are faced by individuals with neuropsychological or mental health issues. While these strategies span a broad spectrum, from introspection and cognitive reframing to behavioral activation and social support seeking, their integration and application remain diverse within clinical contexts. This review endeavors to elucidate the theoretical underpinnings of these strategies, their empirical support, and their practical implications within therapeutic interventions. Furthermore, the intricate interplay between individualized coping techniques and structured therapeutic methodologies will be examined, emphasizing the potential for a holistic treatment paradigm, thereby enhancing therapeutic outcomes and fostering individual resilience.
Analysis of the Lipid Component and the Sterol Ester Fraction for the Detection of Soft Wheat in Durum Wheat Flour and Pasta
Authors: Naviglio Daniele , Perrone Angela , Varchetta Francesca , Trucillo Paolo , Montesano Domenico , Gallo Monica
Published: February 2024

Food adulteration consists of changing the original structure of a food, and so, by its definition, it is a process not admitted by law. Adulterations can not only have commercial consequences, but also hygienic and nutritional ones, and in some cases, they can cause a serious danger to public health. Therefore, it is of great interest to understand and identify the modifications that alter the original chemical composition of a food item (nutrition label). Among the food processing sectors, the pasta food chain is a fascinating production process, which finds its roots in a mixture of a few, simple ingredients; in particular, in its basic formulation to produce pasta, exclusively durum wheat mixed with water is used, while soft wheat and therefore the flour obtained from it are destined for bakeries and the confectionery industry. In this work, a procedure was developed that allows the detection of the possible presence of soft wheat in durum wheat-based products, both in the flour and after the pasta-making process. It is to point out that this adulteration is only commercial fraud and there are no consequences for people’s health. In detail, the method was based on the isolation of the lipid fraction of flours and pastas and using the gas chromatographic analysis of the sterol ester fraction, which were not altered during the pasta-making phase, because they have very high boiling points. Based on the evaluation of some specific ratios between sterol esters, it was possible to trace the percentage of soft wheat present in a mixture with durum wheat, both in flour products and pastas.
Investigation of LASSO Regression Method as a Correction Measurements’ Factor for Low-Cost Air Quality Sensors
Authors: Christakis Ioannis , Sarri Elena , Tsakiridis Odysseas , Stavrakas Ilias
Published: February 2024

Air quality is a subject of study, particularly in densely populated areas, as it has been shown to affect human health and the local ecosystem. In recent years, with the rapid development of technology, low-cost sensors have emerged, with many people interested in the quality of the air in their area turning to the procurement of such sensors as they are affordable. The reliability of measurements from low-cost sensors remains a question in the research community. In this paper, the determination of the correction factor of low-cost sensor measurements by applying the least absolute shrinkage and selection operator (LASSO) regression method is investigated. The results are promising, as following the application of the correction factor determined through LASSO regression the adjusted measurements exhibit a closer alignment with the reference measurements. This approach ensures that the measurements from low-cost sensors become more reliable and trustworthy.
A SWOT: Thematic Analysis of Pedagogical Practices at Inclusive School of Pakistan
Authors: Kamran Mahwish , Bano Nazia , Siddiqui Sohni
Published: February 2024

In Pakistan, where the subject of special/inclusive education is still taboo, there is a need to promote inclusivity in education. However, the journey begins at the grassroots level by accommodating children with disabilities in a mainstream setup at the primary level. This paper presents the findings of an exploratory research study conducted in an inclusive private primary school in Karachi, Pakistan. This case study research draws on the pedagogical practices of classroom teachers in a private primary inclusive school in Karachi where children with disabilities study alongside their peers who do not have special educational needs or disabilities. The research study aimed to explore the strengths, weaknesses, opportunities, and threat factors that could optimize the teaching and learning process of children with special educational needs (CWSN) or children with disabilities (CWD) in the context of an inclusive school located in Karachi, Pakistan. Through an analysis of 16 semi-structured interviews and multiple classroom and field observations, teachers’ understandings of their school’s institutional values and their pedagogical practices to accommodate children with disabilities and inclusion were explored. The interviews were transcribed and analyzed using a SWOT–thematic qualitative method. The results of the SWOT analysis indicate how an inclusive school caters to the strengths of CWD and provides them with opportunities to sustain themselves in an educational setup.
Editorial Introduction to Challenges of Teaching in Today’s Society: Factors Involved in Educational Quality
Authors: Sánchez-Cabrero Roberto , Mañoso-Pacheco Lidia
Published: February 2024

Contemporary Western societies coexist with diverse factors that continually redefine and transform them in response to the myriad social demands they face [...]
The Acute and Long-Term Effects of Olympic Karate Kata Training on Structural and Functional Changes in the Body Posture of Polish National Team Athletes
Authors: Gaweł Eliza , Zwierzchowska Anna
Published: February 2024

The aim of this study was to assess the acute and long-term effects of karate kata training on body posture (range of motion (ROM)) and musculoskeletal pain in elite karate athletes. Twelve kata athletes from the Polish national team participated in the study. A cross-sectional study protocol was used, with direct participatory observation (NMQ-7/6 questionnaire, spinal curvatures and spinal ROM testing, ROM of joints) and natural experiment (225 min of kata training) methods of assessment. Age and number of weekly kata sessions were found to correlate with ROM of the lumbar spine (R = (−0.6), p < 0.05). High increase in the prevalence of lumbar hypolordosis and posterior pelvic tilt was noted after karate training sessions. ROM of the inclination in the sagittal plane differed significantly between the first and second trials, by 10.0 degrees on average. Kata stances and their movement pattern seem to be related to the occurrence of disturbances in the ROM of the internal and external rotations of the hip joints and decreased depth of the lumbar lordosis, pelvic tilt, and their ROM. The locations of the long-term musculoskeletal complaints (NMQ-6) seem to result from compensatory changes that occur in the musculoskeletal structures as a result of elite-level kata training.
Cyclooxygenase-2 (COX-2) Expression in Equine Melanocytic Tumors
Authors: Pimenta José , Prada Justina , Pires Isabel , Cotovio Mário
Published: February 2024

Equine melanocytic tumors are common and have an unusual benign behavior with low invasiveness and metastatic rates. However, tumoral mass growth is usually a concern that can have life-threatening consequences. COX-2 is related to oncogenesis, promoting neoplastic cell proliferation, invasion, and metastasis. The aim of this study was to evaluate the immunohistochemical expression of COX-2 in equine melanocytic tumors. Through extension and intensity of labeling, 39 melanocytomas and 38 melanomas were evaluated. Of the malignant tumors, 13.2% were negative and 63.2% presented a low COX-2 expression. Only 6 malignant tumors presented >50% of labeled cells, 18 malignant and 8 benign had an expression between 21 and 50%, 8 malignant and 3 benign tumors had an expression between 6 and 20%, 1 malignant tumor had an expression between 1 and 5%, and 5 malignant and 28 benign tumors had no expression. Malignant tumors showed higher COX-2 expression than did benign tumors, with statistically significant differences. The low levels of COX-2 may be one of the molecular reasons for the presence of expansive mass growth instead of the invasive pattern of other species, which is related to high COX-2 levels.
Perspectives on SARS-CoV-2 Cases in Zoological Institutions
Authors: Nederlof Remco A. , de la Garza Melissa A. , Bakker Jaco
Published: February 2024

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in a zoological institution were initially reported in March 2020. Since then, at least 94 peer-reviewed cases have been reported in zoos worldwide. Among the affected animals, nonhuman primates, carnivores, and artiodactyls appear to be most susceptible to infection, with the Felidae family accounting for the largest number of reported cases. Clinical symptoms tend to be mild across taxa; although, certain species exhibit increased susceptibility to disease. A variety of diagnostic tools are available, allowing for initial diagnostics and for the monitoring of infectious risk. Whilst supportive therapy proves sufficient in most cases, monoclonal antibody therapy has emerged as a promising additional treatment option. Effective transmission of SARS-CoV-2 in some species raises concerns over potential spillover and the formation of reservoirs. The occurrence of SARS-CoV-2 in a variety of animal species may contribute to the emergence of variants of concern due to altered viral evolutionary constraints. Consequently, this review emphasizes the need for effective biosecurity measures and surveillance strategies to prevent and control SARS-CoV-2 infections in zoological institutions.
Flexibility Potential of Smart Charging Electric Trucks and Buses
Authors: Will Christian , Ocker Fabian
Published: February 2024

In addition to passenger vehicles, battery-electric trucks and buses could offer substantial flexibility to the energy system. Using a Bass diffusion model, we extrapolated the unidirectional charging needs and availability of trucks in five of eleven typical applications, as well as city buses, for Germany until 2040. Combined, these heavy-duty vehicles could provide up to 23 GW of down-regulating flexibility potential (i.e., in case of excess power supply) in 2040. The resulting revenues could contribute to reducing electricity costs for depot operators. These results illustrate the need to provide easy and automated market access to heavy-duty vehicle fleets.
Participación de los Medios Comunitarios y la Democratización de la Comunicación en Ecuador
Authors: Asimbaya Manguia Elizabeth
Published: February 2024

Este estudio tiene como objetivo analizar la participación de los medios comunitarios en Ecuador y su relevancia en el proceso de democratización de la comunicación en el contexto del concurso público de frecuencias y la Ley Orgánica de Comunicación. La investigación emplea una estrategia metodológica que combina la investigación documental con el trabajo de campo, y se realizan cuatro entrevistas semiestructuradas, seleccionadas de manera no aleatoria e intencionada, que se centran en cuatro temas fundamentales: los medios comunitarios, la Ley Orgánica de Comunicación, el Concurso de Público de Frecuencias (año 2016) y la democratización de la comunicación.

Los resultados revelan limitaciones significativas en el alcance del concurso en términos de participación y adjudicación de frecuencias a los medios comunitarios, lo cual afecta la democratización del espectro radioeléctrico. Factores jurídicos, procedimentales y políticos han contribuido a estos resultados. En conclusión, solo un 4% de las frecuencias ofertadas se asignaron a los medios comunitarios, muy por debajo del porcentaje del 34% establecido por la Ley Orgánica de Comunicación. Por otro lado, los medios privados han sido los más beneficiados, lo cual plantea interrogantes acerca de la verdadera existencia de un proceso de democratización de la comunicación en Ecuador.

Este análisis pone de manifiesto la necesidad de revisar y reformar los marcos legales y los procedimientos de asignación de frecuencias para garantizar una mayor participación y representación de los medios comunitarios. Además, se requiere una mayor transparencia y equidad en la distribución de las frecuencias, de manera que se promueva la diversidad y la pluralidad de voces en el espectro radioeléctrico. Estos resultados también evidencian la importancia de fortalecer los mecanismos de participación ciudadana y la promoción de espacios de diálogo y debate sobre la democratización de la comunicación en Ecuador.
Análisis del Impacto Ambiental del Complejo Deportivo del Sur Ramón Unamuno
Authors: Rizzo Adrián , Mayorga Jonathan , Veliz Jonaiker , Acevedo Luis
Published: February 2024

Este proyecto se ha realizado con el fin de conocer la problemática que existe en el complejo deportivo ubicado en la zona urbana de la ciudad de Guayaquil, además de poder brindar una solución a estas.
Farmer’s Income and Allocative Efficiency Analysis in Rice Production in Koto Tangah Subdistrict Padang City
Authors: Leovita Angelia
Published: February 2024

The low productivity of lowland rice (Oryza sativa L.) in Koto Tangah District is affecting farmers’ income. The objectives of this research were to analyze : (i) income from lowland rice cultivation, (ii) factors that influence rice production, and (iii) the efficiency of utilization of lowland rice production factors in Koto Tangah District. The method used in this research was quantitative, using probability sampling techniques with proportional random sampling method and 44 respondents were involved. The data analysis techniques used were income analysis, Cobb-Douglas production function, T-test (partial), F-test (simultaneous), coefficient of determination, and efficiency analysis. Based on the survey results, it was known that the total income from lowland rice cultivation in Koto Tangah District was IDR2,607,860.36/average land area/ MT, and lowland rice cultivation was possible with an R/C value of 1.21. The factors that influenced lowland rice production in Koto Tangah District were land area, seeds, and chemical fertilizers, which significantly affected production levels. In contrast, pesticides, labor within the family, and labor outside the family do not significantly affected lowland rice production in Koto Tangah District. Although production factors such as land area, seeds, fertilizers, pesticides, and family labor (TKDK) were still inefficient, non-family labor (TKLK) had almost reached an efficient level.
Evaluasi Keunggulan Relatif Pertanian Organik dan Non-Organik
Authors: Ibnu Muhammad
Published: February 2024

Para pendukung (supporter) mempromosikan berbagai keunggulan pertanian organik dalam menyediakan bahan pangan bagi umat manusia di bumi ini secara lebih berkelanjutan. Penelitian ini memiliki premis bahwa pertanian non-organik (yang rancu disebut sebagai pertanian konvensional) juga memiliki keunggulan relatif dibandingkan pertanian organik, sehingga argumen yang menyatakan bahwa seluruh pertanian non-organik perlu diubah menjadi pertanian organik adalah tidak tepat. Penelitian ini bertujuan membuktikan premis tersebut dengan mengevaluasi beberapa aspek kritis yang sering menjadi perdebatan, yaitu kebutuhan lahan, keanekaragaman hayati, kualitas air, degradasi lahan, analisis siklus lingkungan hidup, dan perubahan iklim. Penelitian ini bersifat kualitatif dan metode yang digunakan adalah tinjauan literatur terhadap 151 penelitian mengenai pertanian non-organik dan organik. Hasil penelitian menunjukkan bahwa pertanian non-organik memiliki keuntungan relatif dan dapat dilakukan secara berkelanjutan, sehingga dapat menghindari bahaya dan/atau kerusakan akibat mengejar produktivitas yang tinggi. Penelitian ini menyimpulkan bahwa manajemen yang baik tampaknya akan lebih menentukan bagaimana sifat dampak pertanian pada lingkungan. Manajemen pertanian yang baik akan lebih berkontribusi pada lingkungan dan umat manusia dibandingkan ideologi pertanian yang ekstrem, seperti intensif memanfaatkan bahan kimia (tetapi kurang bijaksana) atau tidak memanfaatkan bahan kimia sama sekali.
The applicability of welcome and humanization to the LGBT+ public in primary care: a survey on the qualification of healthcare professionals
Authors: De Melo Gleberton Oliveira , Nascimento Caique Yoshi Ishizuka , Silva Warlen Rezende , Motta Filho Pedro , Cartolano Giulia Guardia , Banzatto Sofia
Published: February 2024

The general objective of the present study was to analyze the applicability of the guidelines of the National Comprehensive Health Policy for Lesbians, Gays, Bisexuals, Transvestites and Transsexuals (PNSI LGBT+), in the Primary Care Units and Family Health Program agreed with the University of Ribeirão Preto (UNAERP) in the city of Ribeirão Preto. In view of the demands and peculiarities inherent to the LGBT+ public, and the importance of welcoming and humanizing, the study aimed to research the training of professionals in the Primary Care Units and the Family Health Program in serving the LGBT+ public. Professionals answered a questionnaire containing 8 questions in line with (PNSI LGBT). This study allowed the identification of the application of educational actions in the routines of health services aimed at promoting self-esteem among LGBT+ people, and the elimination of prejudice for sexual orientation.
Clinical Masks of Tularemia. Problematic Aspects of Diagnosis
Authors: Матиевская Н.В. , Виноградова Т.А. , Волосач О.С. , Данилевич Н.А. , Ярошенко А.Н. , Черняк Л.К. , Красько Ю.П. , Арцименя В.А. , Прокопович В.Г.
Published: February 2024

Заболеваемость туляремией регистрируется на территории Российской Федерации, Республики Беларусь, стран Евросоюза и ряда других. В последние годы отмечена тенденция к росту заболеваемости туляремией. Цель работы – представить клиническое наблюдение групповой вспышки туляремии у троих мужчин, находившихся в природном очаге данной инфекции. В работе представлена групповая вспышка, включавшая три лабораторно подтвержденных случая туляремии. В данных случаях у всех пациентов имели место лихорадка, выраженный регионарный лимфаденит, явления общей интоксикации, наличие первичного аффекта в области входных ворот, причем все случаи были связаны общим эпидемиологическим анамнезом. Однако ни в одном из представленных случаев правильный диагноз не был поставлен изначально. Первичные диагнозы звучали как «внегоспитальная пневмония», «вероятный случай COVID-19-инфекции», «лакунарная ангина», «инфекционный мононуклеоз», что повлекло назначение неэффективного лечения данного заболевания. Лишь тщательно собранный эпидемический анамнез, указавший на посещение всеми пациентами эндемичных по туляремии природных территорий, позволил найти правильное направление диагностического поиска и скорректировать терапию. Все это диктует необходимость повышения информированности медицинских специалистов о клинико-эпидемиологических особенностях туляремии для повышения качества оказания медицинской помощи пациентам с данной инфекцией.

Tularemia is registered on the territory of the Russian Federation, the Republic of Belarus, European Union countries and a number of others. In recent years, there has been a tendency towards an increase in the incidence of tularemia. Purpose of the study – to present a clinical observation of a group outbreak of tularemia in three men who were in an endemic area of tularemia. The paper presents a cluster outbreak that included three laboratory-confirmed cases of tularemia. In the presented cases, all patients had fever, severe regional lymphadenitis, symptoms of general intoxication, the presence of primary affect in the area of the entrance gate, and all cases were associated with a common epidemiological history. However, in none of the presented cases was the correct diagnosis made initially. The primary diagnoses were community-acquired pneumonia, a probable case of COVID-19 infection, lacunar tonsillitis, infectious mononucleosis, which led to the prescription of ineffective treatment for this disease. Only a carefully collected epidemiological history, which indicated that all patients had visited endemic areas for tularemia, made it possible to find the right direction of the diagnostic search and adjust the therapy. All this dictates the need to increase the awareness of medical specialists about the clinical and epidemiological features of tularemia in order to improve the quality of medical care for patients with this infection.
Study of Melatonin Levels in COVID-19 Associated Pneumonia
Authors: Карпович О.А. , Шишко В.И. , Шулика В.Р. , Анацко С.В.
Published: February 2024

В последнее время особый интерес представляет изучение мелатонина – гормона, который благодаря своим противовоспалительным, антиоксидантным и иммуностимулирующим эффектам может рассматриваться как вспомогательное средство как для лечения СOVID-19, так и для профилактики заболевания у лиц с высоким риском инфицирования SАRS-СoV-2. Таким образом, изучение уровня мелатонина у пациентов с СOVID-19-ассоциированной пневмонией, несомненно, представляется актуальной задачей, поскольку поможет оценить его роль в патогенезе и возможность использования в лечении СOVID-19.

Recently, of particular interest has been the study of melatonin, a hormone that, due to its anti-inflammatory, antioxidant and immune stimulating effects, can be considered as an adjuvant both for the treatment of COVID-19 and for the prevention of the disease in individuals at high risk of infection with SARS-CoV-2. Thus, studying the level of melatonin in patients with COVID-19 associated pneumonia undoubtedly appears to be an urgent task, since it will help evaluate its role in the pathogenesis and the possibility of use in the treatment of COVID-19.
Can IgE Level Influence the Ocular Surface Disease Index Score of Patients with Dry Eye Syndrome?
Authors: Ясим Д. , Аль-Рикаби М. , Фадил А.
Published: February 2024

Введение. Синдром сухого глаза (ССГ) – хроническое воспалительное заболевание поверхности глаза. Целью исследования было оценить роль иммуноглобулина IgE при ССГ. Методы. Проспективный сравнительный анализ проводился с октября 2022 г. по май 2023 г., в него было включено 100 случаев ССГ. Пациенты подвергались следующему обследованию: осмотр на щелевой лампе, бесконтактная тонометрия для измерения внутриглазного давления, исследование глазного дна с помощью офтальмологической асферической линзы 90D в качестве стандартного обследования наряду с опросником «Индекс поверхностного заболевания глаз» (OSDI). У них взяли 5 мл венозной крови для исследования. Использовался набор для иммуноферментного анализа IgE (Elecsys IgE II Immunoassay). Результаты. У большего процента пациентов (65%) был зарегистрирован показатель OSDI (2). Больший процент пациентов (90%) был выявлен с уровнем IgE (<150 МЕ). Наблюдалась значимая корреляция между индексом поверхностного заболевания глаз (OSDI) и возрастом пациента с ССГ (р<0,0001), ИМТ (р=0,008), концентрацией IgE (р=0,003). В группе с тяжелой формой CCГ уровень IgE был очень высоким у пациентов с тяжелой формой сухого глаза (90,05±83,4 МЕ) по сравнению с легкой и среднетяжелой степенью с высокой статистически значимой разницей (р=0,002). Выводы. Пациенты с ССГ имеют более высокие показатели индекса поверхностного заболевания глаз (OSDI). Сывороточные иммуноглобулины IgE находятся в обратной зависимости от ССГ.

Background. Dry eye syndrome (DES) is a chronic inflammatory disorder of the ocular surface. The study purposed to assess the roles of immunoglobulin IgE in DES. Methods. A prospective comparison study was carried out from October 2022 to May 2023, enrolled 100 cases of DES. Patients were subjected to the following examination; slit-lamp examination, non-contact tonometry to measure intraocular pressure, fundus examination with 90D as routine examination along with Ocular Surface Disease Index (OSDI) questionnaire. Blood had five ml of venous blood drawn from them. The kits used is IgE (Elecsys IgE II Immunoassay) kit. Results. The greater percentage of patients (65%) documented with OSDI score (2). The greater percentage of patients (90%) were figured with IgE level (<150 IU). There was a significant correlation between OSDI and dry eye patient’s age (p<0.0001), BMI (p=0.008), IgE concentration (p=0.003). In severe group of DES, the IgE level was very high in severely dry eye patients (90.05±83.4 IU) when compared with mild and moderate, with a high statistical significant difference (p=0.002). Conclusions. Patients with DES have higher OSDI scores. Serum immunoglobulins IgE negatively association with DES.
Normalisasi Teks Komentar Instagram Masyarakat Makassar Menggunakan Metode Levenshtein Distence
Authors: Bakhri Isra Andika , Tuhpatussania ST Tuhpatussania , Asfa Nurfajri , Patmawati Patmawati , Mubarak Muhammad Syaban
Published: February 2024

Pertumbuhan pengguna internet dan pengguna instagram di indonesia dapat menjadi peluang yang baik untuk menggali potensi yang dapat digunakan untuk media promosi, sentiment analysis, segmentasi costumer, mapping opinion, menangkap umpan balik (feedback) pelanggan untuk meningkatkan layanan jasa atau barang yang kita tawarkan. Di instagram sendiri banyak tersebar komentar-komentar yang sulit dipelajari oleh mesin dikarenakan banyaknya penggunaan leksikon bahasa gaul atau karena typo atau bisa dikarenakan penggunaan bahasa daerah secara parsial di tiap komentar. Hal inilah yang perlu dievaluasi dalam tahap pre-processing komentar, lebih tepatnya pada tahap normalisasi teks. Seperti di kota makassar misalkan komentar yang tersebar pada akun-akun terkenal di kota tersebut kadang menggabungkan kata baku bahasa indonesia, bahasa gaul indonesia, bahasa baku makassar dan bahasa gaul makassar. Hal inilah yang mendorong penulis untuk mencoba memecahkan masalah normalisasi teks untuk semua komentar ke bahasa baku indonesia agar mempermudah dalam hal pengolahan selanjutnya menggunakan metode levenshtein distence. Dalam hasil pengujian didapatkan masih kurang maksimal dalam normalisasi teks, penulis menduga dikarenakan kata gaul makassar yang ternyata memiliki imbuhan, penggalian morfologi kata yang tidak dilakukan serta belum menerapkan frasa detection untuk bahasa makassar.
PERANCANGAN SISTEM INFORMASI MANAJEMEN PROYEK BERBASIS WEBSITE MENGGUNAKAN CODEIGNITER PADA MATARAM WEB
Authors: Hambali Hambali , Samsumar Lalu Delsi , Wijayanto Panji
Published: February 2024

Manajemen Proyek merupakan sebuah software yang dirancang untuk membantu dalam memanajemen project yang ada pada Developer Mataram Web yang mampu mengatasi permasalahandan menyajikan informasi setiap divisi terhadap admin, Client Dan CEO, yang lebih baik dan terkomputerisasi. Dengan adanya sistem informasi manajemen proyek yang berbasis web sebagai media penghubung setiap divisi sehingga laporan atau perkembangan setiap project pada setiap divisi dapat ditampilkan di satu sistem yang dapat diakses oleh setiap divisi, client maupun CEO. Sistem informasi manajemen proyek berbasis web ini, dikembangkan menggunakan metode pengembangan waterfall, dibangun menggunakan bahasa pemrograman PHP (Framework CodeIgniter 4) dengan pola desain MVC (Model, View, Controller). Hasil dari penelitian ini adalah sistem informasi manajemen proyek berbasis web yang dapat diakses oleh empat level user yaitu admin, CEO, client, dan divisi.