bluuebunny/crossref_metadata_2025 huggingface dataset:
Photodynamic therapy of intradermal metastatic breast cancer (literature review)
Authors: Rakhimzhanova R. I. , Shanazarov N. A. , Turzhanova D. E.
Published: October 2019

In recent years, an increase in the incidence of breast cancer has been observed throughout the world, and in 20% of cases, with the development of intradermal metastases. The possibilities of surgical and radiation treatment of intradermal breast metastases are quite limited, and the effectiveness of polychemotherapy using standard regimens does not exceed 22–27%, while the period of remission, in general, is only 2–3 months. Photodynamic therapy (PDT) is a promising treatment for intradermal metastases of breast cancer. The experience of using PDT in this nosology is quite limited, but the results show its high efficiency and safety. Thus, several Russian studies are devoted to assessing the effectiveness of PDT of intradermal breast metastases with Photolon, a chlorin series photosensitizer. According to the authors, the therapeutic effect was achieved in 85–97% of patients (the percentage of patients with full and partial effect was 73–85%). Studies on the effectiveness of PDT in patients with the same nosology using the Photosens photosensitizer show a slightly lower effectiveness – the therapeutic effect was achieved in 81.8% of cases, while the proportion of patients with full and partial effect was only about 50%. Several studies have been carried out abroad on models of metastatic breast cancer using new photosensitizers (e.g. sodium sinoporphyrin) and new combined PDT regimens (e.g. adjuvant PDT with fluorouracil or Capecitabine). The obtained results demonstrate the promise of new approaches: PDT with sodium sinoporphyrin inhibited the growth of both the tumor itself and its metastases; the use of adjuvant regimens led to an increase in the tumor cells differentiation in the animal model, the cessation of tumor and metastatic foci growth.
Effectiveness of photodynamic therapy of a patient with early central lung cancer and cystic fibrosis
Authors: Borzenko E. S. , Reshetov I. V. , Fatyanova A. S. , Ogdanskaya K. V. , Gafarov M. M. , Romanko Yu. S.
Published: October 2019

The authors describe a clinical observation with full clinical effect after multi-course photodynamic therapy of a patient with central lung cancer and cystic fibrosis using Photoditazine. Photoditazine was administered intravenously at a dose of 0.8 mg/kg 2 hours before the irradiation session. Irradiation parameters: power density – 150 mW/cm2, energy density – 200 J/cm2. In total, 3 courses of photodynamic therapy were performed. As a result of the treatment, a complete regression of the tumor was noted. The patient has been under dynamic observation for 2 years after treatment, no relapse was observed.
Effects of VSTEP on Students’ Learning Motivation at VNU-Hanoi
Authors: Thuy Nga Nguyen , Lan Nguyen Thuy
Published: October 2019

Assessment has played important role in teaching and learning process. The use of the Vietnamese Standardise Test of English Proficiency (VSTEP) to assess the learning outcome of English for all VNU students has created challenges for learners, lectures and manager. This survey study is carried out to examine the effects of VSTEP to 751 students of VNU Hanoi. The findings show that VSTEP has significant impact on students’ learning motivation; however, students are not fully trust that the current English programs could help them achieve the learning target. Besides, a number of students base on the rumor to justify the difficult level of the test and they do not pay much care about the content and format of the test. This study also proposes recommendations to increase the positive effects of the test to enhance the effectiveness of the teaching and learning process.
Application of near critical behavior of equilibrium ratios to phase equilibrium calculations
Authors: Nichita Dan Vladimir , Broseta Daniel , Montel François
Published: October 2019

We examine the asymptotic behavior of the equilibrium ratios (Ki) near the convergence locus in the pressure-temperature plane. When the Equation of State (EoS) is analytical, which is the case of most EoS of engineering purpose, Ki tends towards unity or, equivalently, its logarithm lnKi tends to zero, according to a power ½ of the distance to this locus. As a consequence, if lnKi is expressed as a linear combination of pure component parameters with coefficients only depending on mixture phase properties (i.e., reduction parameters), these coefficients obey a similar power law. Deviations from the ½ power law are thus fairly limited for lnKi and for the reduction parameters (at least in the negative flash window between the convergence locus and the phase boundaries), which can be exploited to speed up flash calculations and for quickly determining approximate saturation points and convergence pressures and temperatures. The chosen examples are representative synthetic and natural hydrocarbon mixtures, as well as various injection gas-hydrocarbon systems.
Management of patients with congenital epidermolysis bullosa
Authors: Karamova A. E. , Albanova V. I. , Monchakovskaya E. S.
Published: October 2019

Congenital epidermolysis bullosa (EB) is a clinically and genetically heterogeneous group of hereditary skin diseases characterized by the formation of blisters and/or erosions in response to minimal trauma. Etiopathogenetic methods for treating the disease are undergoing various stages of clinical research; therefore, external therapy implying caring for affected and non-affected skin remains to be the main treatment method. Such a therapy aims to reduce the healing period of erosive and ulcerative skin defects, thus improving the overall quality of patients’ life. This review sets out to provide clinical recommendations for the management of EB patients developed by different groups of experts, which generalize methods for treating EB patients, main principles of external therapy and relieving subjective sensations, as well as to describe specific situations entailing this pathology.
Studying of the interleukin-36γ expression level in the skin of patients with plaque psoriasis
Authors: Pashkin A. Yu. , Zhukov A. S. , Khairutdinov V. R. , Belousova I. E. , Samtsov A. V. , Garabagiou A. V.
Published: October 2019

Currently, it has been established that the cytokines of the IL-36 family occupy a significant place in the initiation and regulation of the inflammatory process in psoriasis.

Objective: studying the expression level of IL-36γ cytokines in the skin of patients with plaque psoriasis.

Material and methods. Skin biopsy specimens of 31 patients with plaque psoriasis were studied. The comparison group consisted of 20 biopsy samples of the skin of patients with lichen simplex, discoid eczema, lichen planus, mycosis fungoides (plaque stage). As a control group studied the skin bioptates of 10 healthy people. An immunohistochemical study of the skin was carried out using anti-IL-36γ antibodies.

Results. An increase in the relative expression area of IL-36γ in the affected skin of patients with plaque psoriasis (7.4 %) was found, compared with the unaffected areas (0.10 %) and the control group (0 %). The expression of IL-36γ in the skin of patients with psoriasis in the progressive period (8.85 %) was 1.42 times higher than in the stationary period of the disease (6.2 %). A strong direct relationship was revealed (r = 0.71) between the level of IL-36γ expression in the affected skin and the value of the PASI index, a moderate direct relationship between the level of IL-36γ expression and epidermal thickness (r = 0.34). In the affected skin of psoriasis patients, expressed expression of IL-36γ was observed in the upper layers of the epidermis, patients of the comparison group (discoid eczema, lichen simplex, lichen planus, mycosis fungoides) were weak or moderate, in the unaffected areas of the skin of patients with psoriasis and healthy people — weak or absent.

Findings. It was found that the expression of IL-36γ in the skin of patients with plaque psoriasis is significantly higher than with other skin diseases. The data obtained allow us to consider this cytokine as a possible diagnostic marker and use it in the differential diagnosis.
Dermatoscopy in the diagnosis of pigmented nevi
Authors: Bakulev A. L. , Konopatskova O. M. , Stanchina Yu. V.
Published: October 2019

The high incidence of melanoma and unsatisfactory results of its treatment in some cases make the issue of timely diagnostics of pre-melanoma skin pathology, in particular the identification of pre-melanoma pigmented nevi, of great importance and can be used for choice an adequate tactics of treatment. The purpose of the study was to evaluate the informativeness of dermatoscopy in cases of patients with pigmented nevi of skin as a part of melanoma prevention. 168 patients with pigmented nevi were screened. All nevi were photographed with a digital camera SONY Cyber-Shot DSC-H3, first in normal mode with the capture of the localization zone of the tumor and its surrounding tissues, and then in macro mode (“Zoom 10”). To confirm the clinical diagnosis, additional characteristics of the pigment formation on the skin, the manual immersion dermatoscopy, was used using the contact non-polarized HEINE mini 3000 LED dermatoscope. Evaluation of images was carried out using the diagnostic algorithm ABCD and ABCD-E. Our findings suggest that the clinical diagnostic algorithm used by us for detecting signs of the activation of a pigmented nevi is highly informative — the sensitivity is 97.6 %. Performing immersion dermatoscopy allows to increase the informativeness of the clinical and instrumental examination at the preoperative stage up to 98.2 %, which is comparable with the data obtained at the stage of urgent cytological examination: the method sensitivityis 98.2 %.
Fulminant acne. Modern solution of the problem
Authors: Drozhdina M. B.
Published: October 2019

Modern ideas about the etiological factors underlying a rare, serious illness — fulminant acne, the influence of genetic and exposure factors on the formation of the disease, and the pathogenesis of this form of acne are described. The main pathogenetic factors affecting the debut and course of fulminant acne were identified: Cutibacterium and the microbiome of the skin as a whole; sebum overproduction of sebum with the direct participation of dihydrotestosterone, progesterone, insulin-like growth factor-1; features of innate immunity, follicular hyperkeratosis. The clinic, complications and optimal therapeutic tactics at the present stage are described. A clinical case with a successful therapeutic outcome is presented.
Dermatovenereologic health care delivery management in the Russian Federation. Results of 2018
Authors: Kubanov A. A. , Bogdanova E. V.
Published: October 2019

The paper presents the analysis of resources and the results of work of dermatovenereologic healthcare organizations in 2018. The dynamics of incidence of sexually transmitted infections, and the dynamics of prevalence of skin disorders in the Russian Federation is described.
Analisis Kemampuan Berpikir Logis Matematis Siswa SMP Kelas VII dalam Memecahkan Masalah Matematika Ditinjau dari Gaya Belajar
Authors: Fitriyah Desi Melatul , Indrawatiningsih Nonik , Khoiri Miftahul
Published: October 2019

Kemampuan berpikir logis memiliki peran penting dalam pemecahan dan pembelajaran konsep matematika dan untuk meningkatkan hasil belajar. Penelitian ini adalah penelitian kualitatif deskriptif yang bertujuan untuk mendeskripsikan kemampuan berpikir logis siswa kelas VII dalam memecahkan masalah matematika yang ditinjau dari gaya belajar pada pokok bahasan aritmatika sosial. Subjek dalam penelitian ini berjumlah 3 siswa dengan siswa bergaya belajar visual, auditori dan kenestetik. Pengumpulan data menggunakan angket gaya belajar, tes kemampuan berpikir logis, wawancara dan dokumentasi. Berdasarkan hasil penelitian, subjek bergaya belajar visual memiliki kemampuan berpikir logis yaitu pada tahap klasifikasi, tahap menghubungkan, tahap menghitung dan tahap menarik kesimpulan. Subjek bergaya belajar auditori memiliki kemampuan berpikir logis yaitu pada tahap klasifikasi, tahap menghubungkan, tahap menghitung dan tahap menarik kesimpulan. Sedangkan subjek bergaya belajar kinestetik memiliki kemampuan berpikir logis yaitu pada tahap klasifikasi, tahap menghubungkan dan tahap menarik kesimpulan.

 

The ability to think logically has a vital role in solving and learning mathematical concepts, its to improve learning outcomes. This research is descriptive qualitative research that aims to describe the ability of students to think logically in class VII in solving mathematical problems in terms of learning styles on the subject of social arithmetic. The subjects in this study amounted to 3 students with students learning styles visual, auditory, and kinesthetic. Data collection uses learning style questionnaires, logical thinking skills tests, interviews, and documentation. The results of the study show that three stages of the logical thinking ability with visual learning style subject, namely the connecting stage, the counting stage, and the conclusion drawing stage. Auditory learning style subjects can think logically that is at the classification stage, the connecting stage, the counting stage, and the conclusion drawing stage. Whereas the kinesthetic learning style subject can think logically, that is at the classification stage, the connecting stage, and the conclusion drawing stage.
Upaya Meningkatkan Keaktifan dan pemahaman Konsep Gaya Magnet Melalui Modul Kartun Berbasis Experiental Learning
Authors: Megariyani Krismayana , Mursidik Elly’s Mersina , Listiani Ivayuni
Published: October 2019

Penelitian ini bertujuan untuk upaya meningkatkan keaktifan dan pemahaman konsep gaya magnet melalui modul kartun berbasis experiential learning pada siswa kelas VI. Penelitian dilakukan pada bulan April 2019 di SDN Gelanglor, Kecamatan Sukorejo, Kabupaten Ponorogo. Jenis penelitian ini adalah penelitian tindakan kelas yang terdiri dari tiga siklus yaitu siklus 1, siklus II dan siklus III. Penelitian ini dilakukan enam kali pertemuan dengan materi gaya magnet.Subjek penelitian adalah peserta didik kelas VI dengan jumlah peserta didik 29 orang. Teknik pengumpulan data dengan cara observasi dan tes. Hasil menujukkan keaktifan dan pemahaman konsep melalui penerapan modul  kartun berbasis experiential learning meningkat dengan sangat baik. Prosentase peningkatan keaktifan 100% dengan nilai rata-rata keaktifan 93,10 dan pemahaman konsep mencapai 100% dengan nilai rata-rata pemahaman konsep 92,76. Sehingga bisa dilihat kelebihan penerapan modul kartun berbasis experiential learning adalah menjadikan peserta didik lebih aktif, kekurangan dari modul ini adalah membutuhkan waktu yang sangat lama untuk menyiapkan materi pembelajaran yang akan diajarkan.

 

This study aims to improve the activity and understanding of the concept of magnetic force through cartoon modules based on experiential learning in class VI students. The study was conducted in April 2019 at SDN Gelanglor, Sukorejo District, Ponorogo Regency. This type of research is a class action research consisting of three cycles, namely cycle 1, cycle II and cycle III. This study was conducted six times with magnetic force material. Subjects were class VI students with 29 students. Data collection techniques by observation and tests. The results showed activeness and understanding of the concept through the application of experiential learning-based cartoon modules improved very well. The percentage increase of 100% activeness with an average value of 93.10 activeness and understanding of the concept reached 100% with an average value of 92.76 concept understanding. So that it can be seen that the advantages of the application of cartoon modules based on experiential learning is to make students more active, the disadvantage of this module is that it takes a very long time to prepare learning material to be taught.
Pengembangan E-Modul Berbasis Kontekstual pada Materi Program Linear Kelas XI
Authors: Afrianti Reny Eka Nur , Qohar Abd.
Published: October 2019

Penelitian ini bertujuan untuk mengembangkan modul berbasis elektronik (E-Modul) pada materi program linier dengan menggunakan masalah yang kontekstual. E-Modul yang dikembangkan merupakan modul berbasis android. Respoden penelitian ini adalah siswa kelas XI SMA Negeri 1 Talun. Media dikembangkan dalam tiga tahap. Tahap pertama adalah tahap analisis produk yang dikembangkan yaitu terdiri dari analisis concept, design, dan collecting materials. Tahap kedua adalah tahap mengembangkan produk awal yaitu terdiri dari pembuatan power point yang kemudian di-upload dalam program web to apk. Saat pengembangan produk gambar dan animasi yang dipilih disesuaikan dengan usia siswa sekolah menengah agar konsep mudah dipahami siswa. Produk dibuat dengan mengangkat cerita kontekstual dalam kehidupan sehari-hari yang dipahami siswa sekolah menengah. Tahap ketiga adalah uji coba produk yang terdiri dari uji ahli dan uji coba skala kecil. Uji ahli terdiri dari validasi media dan validasi materi. Hasil menunjukkan bahwa media pembelajaran E-Modul yang dikembangkan valid dan praktis. Nilai kevalidan yang diperoleh yaitu nilainya 3,2.

 

This study aims to develop electronic-based modules (E-Modules) in linear program material using contextual problems. The developed e-module is an android-based module. The respondents of this study were students of class XI of SMA Negeri 1 Talun. The media developed in three stages. The first stage is the product analysis stage, which is developed, which consists of the analysis of concepts, design, and collecting materials. The second stage is the stage of developing the initial product, which consists of making powerpoints that are then uploaded on the web to an application program. When developing selected drawing and animation products, it is adjusted to the age of secondary school students so that the concepts are easily understood by students. Products are made by bringing up contextual stories in everyday life that are understood by middle school students. The third stage is product trials consisting of expert trials and small scale trials. Expert tests consist of media validation and material validation. The results show that the E-Module learning media developed are valid and practical. The validity value obtained is 3.2.
Kemampuan Spasial dalam Pengkonstruksian Jaring-Jaring Kubus dan Balok
Authors: Wulandari Shinta
Published: October 2019

Jaring-jaring dapat membantu siswa membuat konsep hubungan antara objek dua dimensi dan tiga dimensi. Namun masih ada ketidakakuratan dalam menyusun jaring-jaring yang disebabkan oleh kemampuan spasial yang lemah. Tujuan dari penelitian ini adalah untuk menggambarkan kemampuan spasial siswa dalam membangun jaring-jaring kubus dan balok. Subjek penelitian adalah empat puluh siswa Sekolah Dasar kelas lima. Dari empat puluh siswa dipilih dua siswa untk diwawancara lebih mendalam terkait penyelesaian tugas jaring-jaring kubus dan balok. Hasil penelitian menunjukkan bahwa dalam menyelesaikan tugas penyusunan jaring-jaring kubus dan balok, subjek menunjukkan kelemahan dalam kemampuan orientasi spasial dan visualisasi spasial. Kelemahan pada orientasi spasial terlihat pada kemampuan subjek untuk melihat objek dari sudut pandang tertentu yaitu dalam mengenali dua jaring-jaring yang kongruen tetapi dianggap tidak kongruen. Sedangkan kelemahan visualisasi spasial nampak pada saat subjek yang tidak dapat membayangkan bahwa jaring-jaring dapat dilipat menjadi kubus dan balok.

 

Nets can help students conceptualize the relationship between two-dimensional and three-dimensional objects. But there are still inaccuracies in composing the webs caused by weak spatial ability. The purpose of this study is to describe the spatial ability of students in constructing cube and beam webs. The research subjects were forty-fifth-grade elementary school students. Of the forty students, two students were chosen to be interviewed more deeply related to the completion of the task of the cube nets and the beam. The results showed that in completing the task of arranging cube and beam nets, the subject showed weaknesses in the ability of spatial orientation and spatial visualization. Weaknesses in spatial orientation are seen in the subject's ability to see objects from a certain point of view, namely in recognizing two nets that are congruent but considered incongruent while the weaknesses of spatial visualization are seen when subjects cannot imagine that the webs can be folded into cubes and blocks.
Analisis Kesalahan dalam Menyelesaikan Masalah Segi empat Ditinjau dari Perkembangan Kognitif
Authors: Setiawan Doni Indra , Widodo Sri Adi
Published: October 2019

Penelitian ini bertujuan untuk mendeskripsikan kesalahan yang dilakukan siswa dalam menyelesaikan masalah segi empat pada fase konkret, dan fase transisi. Penelitian ini menggunakan penelitian kualitatif deskritptif dengan subjek penelitian sebanyak 4 subjek yang diambil berdasarkan purposive sampling. Teknik pengumpulan data menggunakan tes. Teknik analisis data menggunakan model yang dikembangkan oleh Miles dan Huberman yaitu reduksi data, penyajian data, dan menarik kesimpulan/verifikasi data. Kesalahan yang sering dilakukan siswa fase konkret yaitu siswa salah dalam menggambar bangun yang diceritakan soal, salah dalam menentukan rumus dan tidak menuliskan rencana penyelesaian, salah melakukan prosedur penyelesaian dan tidak menggunakan rumus secara semestinya, serta tidak melakukan pemeriksaan kembali jawaban. Kesalahan yang sering dilakukan siswa fase transisi yaitu siswa salah dalam menggambarkan bangun yang diceritakan dalam soal, salah dalam menuliskan rumus yang perlu digunakan, pada tahap melaksanakan rencana tidak terjadi kesalahan, serta tidak melakukan pemeriksaan kembali jawaban.

 

This study aims to describe the mistakes made by students in solving rectangular problems in the concrete phase and the transition phase. This study uses descriptive qualitative research with four research subjects taken based on purposive sampling. Data collection techniques using the test. Data analysis techniques using a model developed by Miles and Huberman, namely data reduction, data presentation, and concluding/verification of data. Students often made mistakes. In the concrete phase, students making drawings that are told about problems.  Errors in determining formulas and not writing completion plans, error when doing completion procedures and not using formulas properly, and not re-checking answers. In the transition phase, students who are wrong in describing the shapes told in the problem. Errors in writing the formula that needs to be used, at the stage of carrying out the plan there is no error, and not re-checking the answers.
Penerapan Model Discovery Learning pada Materi Pemanasan Global untuk Meningkatkan Keterampilan Berpikir Kritis Peserta Didik
Authors: Haryanti Novita , Widodo Antonius Tri , Arfiani Yuni
Published: October 2019

Penelitian ini bertujuan untuk mengetahui peningkatan keterampilan berpikir kritis peserta didik dengan menggunakan model discovery learning pada materi pemanasan global. Penelitian ini dilakukan pada kelas VII di SMP Negeri 2 Taman Pemalang tahun pelajaran 2018/2019. Pengambilan sampel penelitian menggunakan teknik multi stage random sampling dengan mengambil dua kelas dari populasi untuk kelas kontrol dan kelas eksperimen. Pengumpulan data menggunakan metode tes dengan soal uraian. Hasil penelitian menunjukkan bahwa kelas eksperimen yang menggunakan model discovery learning keterampilan berpikir kritis yang di diperoleh peserta didik meningkat. Hal ini ditunjukkan dari pada kenaikan persentase peserta didik yang mulanya 100% pada kategori kurang kritis menjadi 4% pada kategori sangat kritis, 56% kritis, 36% cukup kritis dan 4% kurang kritis.

 

This study aims to determine the increase in students' critical thinking skills by using discovery learning models on global warming material. This research was conducted in class VII at Taman Pemalang State Middle School 2 in the 2018/2019 academic year. Sampling research uses a multi-stage random sampling technique by taking two classes from the population for the control class and the experimental class. Data collection using test. The results showed that the experimental class that used the discovery learning model of critical thinking skills gained by students increased. This is shown from the increase in the percentage of students who initially 100% in the less critical category to 4% in the very critical category, 56% critical, 36% quite critical, and 4% less critical.
Upaya Peningkatan Hasil Belajar dalam Pembelajaran IPA Materi Gaya Magnet dengan Model Inquiry Berbantuan LKS pada Peserta Didik Kelas V SD
Authors: Fitriani Deasy Nur , Setiyadi Dwi , Listiani Ivayuni
Published: October 2019

Berdasarkan hasil observasi awal peneliti di kelas V SD Negeri Tawangrejo 05 Kecamatan Gemarang Kabupaten Madiun menunjukkan masih rendahnya hasil belajar peserta pada mata pelajaran IPA. Penelitian ini bertujuan untuk meningkatkan hasil belajar peserta didik pada mata pelajaran IPA materi gaya magnet dengan menggunakan model inquiry berbantuan LKS. Metode penelitian ini menggunakan metode penelitian tindakan kelas. Prosedur penelitian tindakan kelas ini berbentuk siklus. Dimana setiap siklus terdiri dari lima tahap yaitu perencanaan, pelaksanaan tindakan, observasi, refleksi dan rekomendasi. Teknik pengumpulan data pada penelitian ini yaitu melalui observasi dan tes. Pengumpulan data ini menggunakan instrument berupa lembar observasi keaktifan dan keterampilan peserta didik selama proses pembelajaran berlangsung, sedangkan untuk mengetahui hasil belajar dari peserta didik digunakan tes. Hasil penelitian ini menunjukkan adanya peningkatan hasil belajar peserta didik dari siklus I ke siklus II yaitu pada skor keaktifan peserta didik meningkat sejumlah 21,42%, skor keterampilan peserta didik sejumlah 14,28%, dan tes hasil belajar peserta didik sejumlah 28,57%. Berdasarkan hasil penelitian dan pembahasan, maka dapat disimpulkan bahwa model inquiry dengan berbantuan LKS mampu meningkatkan hasil belajar peserta didik pada mata pelajaran IPA materi gaya magnet.

 

Based on the results of preliminary observations of researchers in class V SD Negeri Tawangrejo 05 Gemarang District, Madiun shows the low learning outcomes of participants in natural science subjects. This study aims to improve student learning outcomes in science subjects' magnetic force material by using the LKS-assisted inquiry model. This research method uses classroom action research methods. This class action research procedure is in the form of a cycle. The cycle consists of five stages, namely planning, implementing action, observation, reflection, and recommendations. Data collection techniques in this study are through observation and tests. This data collection uses an instrument in the form of an observation sheet of activeness and skills of students during the learning process, while to know the learning outcomes of students using a test. The results of this study indicate an increase in student learning outcomes from cycle I to cycle II, namely the student activity score increased by 21.42%, student skills scores by 14.28%, and student learning outcomes test amounted to 28.57 %. Based on the results of research and discussion, it can be concluded that the inquiry model with LKS-assisted learning can improve student learning outcomes in science subjects' magnetic force material.
Peningkatan Creative Thinking Skill Peserta Didik melalui Model Cooperative Learning Berbantu Peta Konsep pada Tema Pencemaran Lingkungan
Authors: Mukarrom Lailil , Widiyanto Bayu , Arfiani Yuni
Published: October 2019

Penelitian ini bertujuan mengetahui peningkatan creative thinking skill peserta didik antara penerapan model cooperative learning berbantu peta konsep dengan penerapan model cooperative learning tanpa peta konsep pada tema pencemaran lingkungan. Penelitian ini dilakukan pada peserta didik kelas VII di SMP Negeri 8 Pemalang. Desain penelitian ini adalah pretest-postest control group design. Teknik pengambilan sampel yang digunakan adalah purposive sampling. Pengujian penelitian ini menggunakan uji paired sample t-test. Instrumen yang digunakan yaitu soal pretest dan postest berbentuk uraian dengan 7 soal,  lembar observasi dan lembar penilaian hasil tugas mandiri peserta didik.  Hasil penelitian menunjukkan ada peningkatan yang signifikan dengan nilai signifikansi pada kelas eksperimen sebesar 0,016<0,05 dan pada kelas kontrol sebesar 0,013<0,05 antara penerapan model cooperative learning berbantu peta konsep dan model cooperative learning tanpa peta konsep untuk meningkatkan creative thinking skill peserta didik pada tema pencemaran lingkungan.

 

This study aims to determine the improvement of students' creative thinking skills between the application of cooperative learning models assisted with concept maps and the implementation of cooperative learning models without concept maps on the theme of environmental pollution. This research was conducted on grade VII students at SMP Negeri 8 Pemalang. The design of this study was the pretest-posttest control group design. The sampling technique used was purposive sampling. The testing of this study used a paired sample t-test. The instrument used was a matter of pretest and posttest in the form of a description with seven questions, an observation sheet, and an assessment sheet of students' independent assignment results. The results showed a significant increase with a significance value in the experimental class of 0.016 <0.05 and in the control class of 0.013 <0.05 between the application of cooperative learning models assisted with concept maps and cooperative learning models without concept maps to improve participants' creative thinking skills students on the theme of environmental pollution.
Implementasi Concept Mapping Bervisi SETS Untuk Memberdayakan Kemampuan Berpikir Kritis
Authors: Khasanah Ismiyatun , Fatkhurrohman M. Aji , Kusuma Mobinta
Published: October 2019

Penelitian ini bertujuan untuk mengetahui bahwa metode concept mapping bervisi SETS dapat meningkatkan kemampuan berpikir kritis peserta didik. Penelitian ini menggunakan pendekatan kuantitatif dan jenis penelitian ini adalah penelitian eksperimen. Desain penelitian yang digunakan adalah pretest and postest group design. Peta konsep yang digunakan dalam bentuk fill in mapp sehingga peserta didik diminta untuk melengkapi peta konsep yang telah disediakan. Penelitian ini di analisis menggunakan uji t. Hasil yang diperoleh dari analisis data pretest dan postest menggunakan uji t bahwa terdapat perbedaan antara hasil pretest dan postest dengan nilai signifikansi 0,00 < 0,05. Sehingga hipotesis pada penelitian dapat diketahui bahwa ditolak dan diterima.  ditolak karena hasil uji t menyatakan bahwa ada perbedaan hasil pada pretest dan postest dengan nilai postest lebih tinggi dari pada nilai pretest sehingga hipotesis yang dapat diterima  yaitu ada peningkatan hasil belajar dan berpikir kritis peserta didik melalui metode concept mapping bervisi SETS.

 

This study aims to determine that the SETS vision concept mapping method can improve students' critical thinking skills. This study uses a quantitative approach and this type of research is experimental research. The research design used was the pretest and post-test group design. The concept map used in the fill-in app form so that students are asked to complete the concept map that has been provided. This study was analyzed using t-test. The results obtained from the pretest and post-test data analysis used the t-test that there were differences between the results of the pretest and post-test with a significance value of 0.00 <0.05. So that the hypothesis in the study can be seen that rejected and accepted. rejected because the results of the t-test state that there are differences in the results at the pretest and post-test with the post-test value higher than the pretest value so that the accepted hypothesis is that there is an increase in students' learning and critical thinking through SETS vision concept mapping method.
Formulasi Ekastrak Kulit Buah Naga Merah (Hylocereus polyrhizus) Sebagai Pewarna Alami Dalam Sediaan Lipstik
Authors: Yulyuswarni Yulyuswarni
Published: October 2019

Hasil pengawasan yang dilakukan oleh BPOM selama bulan Januari-Juni tahun 2016 menemukan 43 item kosmetika mengandung bahan berbahayaantara lain merkuri, hidrokuinon, asam retinoat, deksametason, klindamisin, serta bahan pewarna merah K3 dan merah K10. Kosmetika yang mengandung bahan pewarna berbahaya beberapa diantaranya adalah lipstik. Penggunaan zat warna berbahaya dalam sediaan lipstik sendiri dapat menjadi pemicu masalah kesehatan khususnya pada kulit. Salah satu alternatif yang bisa dilakukan adalah dengan menggunakan pearna alami dalam sediaan lipstik. Kulit buah naga merah (Hylocereus polyrhizus) merupakan tanaman yang mengandung pigmen warna betalain yang bisa dimanfaatkan sebagai pewarna alami dalam formulasi sediaan lipstik). Penelitian ini bertujuan untuk membuat sediaan lipstik menggunakan ekstrak kulit buah naga merah (Hylocereus polyrhizus) sebagai pewarna alami dengan konsentrasi 17.5 %, 20%, 22,5% dan 25%, dan mengetahui mutu sediaan lipstik berupa organoleptis, homogenitas, pH, titik lebur, daya lekat, iritasi serta kesukaan panelis. Penelitian yang dilakukan bersifat eksperimental kualitatif dengan menganalisis hasil evaluasi sediaan lipstik dengan cara membandingkan data yang diperoleh dengan persyaratan sediaan lipstik dan ANAVA. Hasil penelitian menunjukkan bahwa sediaan lipstik ekstrak kulit buah naga merah (Hylocereus polyrhizus) dengan variasi konsentrasi memiliki peningkatan warna yaitu dari cokelat muda menjadi cokelat tua, berbau khas, dan memiliki konsistensi setengah padat cenderung keras. Seluruh formula tidak homogen, memiliki pH antara 5.3-6,1. Titik lebur  530C-55.30C, perbedaan titik lebur berbeda secara bermakna antara F0 dengan F3 dan F4, kemudian F1 dengan F2, F3, dan F4. Seluruh formula memiliki daya lekat yang kurang baik dan tidak menyebabkan iritasi. Uji kesukaan tidak dilakukan karena tidak ada formula yang memenuhi semua syarat mutu sediaan lipstik
Efektivitas Ekstrak Batang Pisang Kepok (Musa x paradisiaca Linn.) Terhadap Pertumbuhan Bakteri Streptococcus pyogenes.
Authors: MARHAMAH MARHAMAH , Putri Indah Wahyuni
Published: October 2019

Batang pisang memiliki kandungan antibakteri yaitu tanin, flavonoid, alkaloid, steroid. Berdasarkan penelitian yang dilakukan Marhamah (2014) tentang resistensi bakteri Gram positif salah satunya yaitu Streptococcus. sp didapatkan hasil 100% Streptococcus sp resisten terhadap antibiotik gentamisin, amoksilin, dan cefadroxile. Streptococcus pyogenes merupakan bakteri Gram positif penyebab utama faringitis, kasus faringitis di dunia sebesar 616 juta/ tahun, di Indonesia terjadi pada anak-anak sebesar 18%. Penelitian ini bertujuan untuk mengetahui efektivitas ekstrak batang pisang kepok (Musa x paradisiaca L.) dalam menghambat pertumbuhan bakteri Streptococcus pyogenes. Penelitian ini bersifat eksperimental dengan rancangan penelitian Rancangan Acak Lengkap (RAL). Variabel bebas yaitu ekstrak batang pisang kepok  dengan konsentrasi 10%, 20%,30%, 40%, 50%, 60%, 70%, 80%, 90%, 100% dan variabel terikat yaitu pertumbuhan bakteri Streptococcus pyogenes. Metode dalam pemeriksaan adalah difusi  Kirby-bauer. Penelitian dilakukan di laboratorium Bakteriologi Jurusan Analis Kesehatan Poltekkkes Tanjungkarang pada bulan Maret-Mei 2017. Analisa data  adalah One-way Anova dan dilanjutkan dengan uji BNT. Hasil analisa data p=0.000 (p< 0.05)  artinya, ekstrak batang pisang kepok dapat menghambat pertumbuhan bakteri Streptococcus pyogene, pada konsentrasi 50%-100% dengan diameter zona sebesar 6,71-9,45 mm.
EFEKTIVITAS EKSTRAK BUNGA CENGKEH (Eugenia aromatica) TERHADAP PERTUMBUHAN BAKTERI Staphylococcus aureus
Authors: HUDA MISBAHUL , Djayasinga Rodhiansyah , NINGSIH DEVI SULISTIA
Published: October 2019

Staphylococcus aureus  menyebakan  infeksi kulit (bisul, impetigo, furunkel, infeksi luka), infeksi pernapasan (pneumonia, abses paru), Invasif (septikemia, abses dalam, sindrom syok toksik), traktus gastrointestinal, dan infeksi terkait alat. Salah satu tanaman tradisional yang sering digunakan sebagai obat tradisional adalah bunga cengkeh. Kandunga senyawa antibakteri di dalam bunga cengkeh yaitu flavonoid, tannin, alkoloid, dan euganol.  Jenis penelitian yang dilakukan adalah experimental dengan rancangan penelitian acak lengkap (RAL). Variabel bebasnya adalah ekstrak bunga cengkeh (Eugenia aromatica)  dengan konsentrasi 10%, 20%, 30%, 40%, 50%, 60%, 70%, 80%, 90%, dan 100% dan variabel terikatnya adalah uji daya hampat pertumbuhan bakteri Staphylococcus aureus. Tempat penelitian dilakukan di Laboratorium Bakteriologi Jurusan Analis Kesehatan  Poltekkes Tanjung karang pada bulan April – Juni. Hasil penelitian menunjukkan bahwa ekstrak bunga cengkeh konsentrasi 10% sampai dengan 100% mampu menghambat pertumbuhan bakteri Staphylococcus aureu. Konsentrasi terendah dari ekstrak bunga cengkeh (Eugenia aromatica) yang dapat menghambat adalah konsentrasi 10% dengan rerata 15,87 mm.dan konnsentrasi tertinggi ekstrak bunga cengkeh (Eugenia aromatica) konsentrasi 100% didapatan  rerata 21,40. Sedangkan ekstrak bunga cengkeh pada konsentrasi 70% dengan rerata 19,16 mm sudah efektif menghambat pertumbuhan bakteri apabila dibandingkan dengan kontrol positif antibiotik amikasin dengan rerata 18,8 mm.
O profundo e sua expressão: a relação entre filosofia e mística em Bergson/La profondeur et son expression: les relations entre philosophie et mystique chez Bergson
Authors: Ferreira Rildo Da Luz
Published: October 2019

Nosso estudo não consistirá unicamente no exame do pensamento religioso de Bergson. E também não será uma reflexão específica sobre sua filosofia da natureza ou ainda sobre sua filosofia da ciência. Nosso objetivo se situa na junção das ideias bergsonianas sobre o natural e o sobrenatural, sobre o filosófico e o religioso, sobre a ciência e a metafísica. Mas tal empreitada corre um grande risco: o de justapor, em um primeiro momento, estes diferentes campos de reflexão para, em um segundo momento, tentar reuni-los. O élan vital nos parece o caminho mais seguro para nos proteger deste risco. Uma vez que ele está na intersecção de diferentes ordens do pensamento de Bergson, ele não favorece apenas sua articulação, ele o demanda. Consequentemente, é do ponto de vista interno à filosofia da natureza que aparece a questão religiosa em Bergson. Tal é a hipótese que formulamos.Resumé:  Notre étude ne consistera pas uniquement en l’examen de la pensée religieuse chez Bergson. Elle ne será pas non plus une réflexion spécifique sur sa philosophie de la nature ou encore sur sa philosophie des sciences. L’objet de notre recherche se situe à la jonction des idées bergsoniennes sur le religieux, sur la science et la métaphysique. Mais une telle enterprise court un risque majeur, celui de juxtaposer, dans un premier temps, ces différentes champs réflexifs pour, dans un deuxième moment, tenter de les reunir. L’élan vital nous apparaît le moyen le plus certain de prevenir ce risque. Parce qu’il est à l’intersection des différents ordres de la pensée de Bergson, il ne favorise pas seulement leur articulation, il l’exige. Par conséquent, c’est d’um point de vue interne à la philosophie de la nature elle-même que se pose la question religieuse chez Bergson. Telle est l’hypothèse que nous formulons. Mots-clés: durée, intuition, élan vital, mystique
METHODOLOGY OF RESEARCH OF PUBLISHING BUSINESS HISTORY
Authors: Shpak Victor
Published: October 2019

This article is devoted to analysis of the modern methods and methodology of research of publishing business history.
The urgency of research is that the printed word is crucial in development of the independent Ukraine. It forms a socio-political thought, affects the mentality of the Ukrainian people, its spiritual life and revival of historical traditions and development of economy. The necessity of developing the chosen theme is also amplified due to the absence of a special study in the national science, which would include comprehensive system analysis of publishing business, combining all the interrelated components of publishing process. The methodological basis of the proposed research is the main principles of historicism and scientific objectivity, the main methods of scientific and historical knowledge, modern conceptual approaches to study phenomenon of small business in the context of publishing activities. This means the whole of general scientific and special methods and approaches, which can be divided into three main groups: methods of obtaining and accumulation of information; methods of generalization; methods that can explain the results and draw conclusions.The study of the object of analysis is impossible without a digression into the past and clarifying its roots. Consequently the author made an attempt to generalize methodological basis of research based on the main principles of historicism and scientific objectivity, the fundamental provisions of both domestic and individual foreign historical, philosophical and political concepts on the laws and certain specific features of formation and development of publishing. It is concluded that applying general scientific and special methods and approaches makes it possible to trace the main stages and trends in development of publishing business, to clarify its specificity, its role and place at different stages of its development. It is possible to carry out the research tasks as to a systematic and complex analysis of the state of small publishing business, its impact on development of civil society through formation of middle class and comprehensive democratization of all public and state institutions based on empirical and theoretical methods of research.
Cost Implications for an In-House University Timetabling System
Authors: Raseonyana Wame , Anderson George , Nkgau Tallman
Published: October 2019

This paper reports on a study on the examination timetabling problem faced in universities, focusing on the problem as it exists at the University of Botswana (UB). Examination timetabling is well researched and many different algorithms have been used in an attempt to produce timetable solutions that meet various objectives of institutions as well as theoretical objectives. Our research tries to produce an optimal examination timetable, which takes into consideration constraints imposed by users of timetables in UB as well as best-practice constraints found in the literature. Most African universities have financial constraints that make cost-effective solutions that take advantage of readily available research results and frameworks critical to their survival and strategic goals. In our paper, we analyse the cost implications of in-house development of an examination scheduling system solution that will produce improved schedules and reduce costs. We take into account the cost of software tools and frameworks we have employed as well as the cost of getting data and actual software engineering of a timetabling solution. Our results suggest that the benefits of this approach are great, since the cost is low while the quality of resulting timetables is good.
Dimensions of perceived risk of mobile banking apps: An empirical investigation of South African retail banking customers.
Authors: Thusi Philile , Maduku Daniel K.
Published: October 2019

Banking transactions carried out in the uncertain conditions of mobile commerce involve high

levels of perceived risk and require substantial levels of trust. Therefore, gaining customer trust and reducing the influence of risk is imperative to developing and nurturing long-lasting and strong relationship between customers and retail banks. However, limited research is currently investigating the effects of overall perceived risk and trust on retail banking customers use of mobile commerce, particularly from the perspective of emerging African economies. This study investigates the effects of perceived risk and institution-based trust on the use of mobile banking apps among South African retail bank customers. The model was tested using responses obtained from 352 users of the mobile banking services of the five major retail banks (ABSA, Capitec, FNB, Nedbank, and Standard Bank) in South Africa. The findings of this study suggest that institution- based trust has a significant positive influence on use behaviour of mobile banking apps. Furthermore, perceived risk has a significant negative influence on use behaviour; and, lastly, institution-based trust is found to have a significant negative influence on perceived risk.
Mr. The Task and Ministry of Peacemaking in Mindanao: Understanding a Peacemaker’s Recipe for Peace
Authors: Asiones Noel G.
Published: October 2019

At a time when the role of religion in reducing global conflicts and the authority of its leaders are being questioned, studies that would link religion and conflict may fill in a gap in knowledge. To address this gap, this study seeks to gain an understanding of Orlando Cardinal Quevedo’s task and ministry of peacemaking in the long-running conflict in the Southern Mindanao region. Given the recent signing of the Bangsa Moro Organic Law as the highly expected solid basis for a peaceful and prosperous Mindanao, it is timely to look back and pay closer attention to the key role that he played as a peace advocate. To achieve this end, it organized and conducted a content analysis of his writings and interviews about peace and its imperatives. Findings show that his words, firmly rooted in the conflict’s historical past and yet open to the realities of the present, encompassed and helped disclose his practical wisdom, consensus-driven approach, and Catholic perspectives of its underlying issues and challenges. The lessons and insights that are uncovered from his writings may serve as a grounded recipe for those who would follow in his footsteps to learn and re-appropriated in a hopefully not an unending task and ministry of peacemaking in today’s world.
W: SPATIAL WEIGHT MATRIX DIVERSITY AND ITS IMPACT ON SPATIAL ANALYSIS RESULTS
Authors: Mackova Simona
Published: October 2019

Spatial econometrics presents irreplaceable tool for regional analysis. Omitting additional information about geographical location of observed units could neglect some important influences. The spatial weight matrix W determining neighbourhood relations and degree of influence between observed units belongs to the main components of spatial analysis. Various specification approaches of this non-stochastic matrix could be applied. There is a commonly held belief that spatial regression models are sensitive to spatial weight structure. Some analytics consider it as a myth and points out incorrect interpretation of the model coefficients or misspecified models. Does it really matter what kind of specification is used? This contribution brings an empirical example of several approaches to neighbourhood specification and compares obtained results. According to findings of this analysis, especially spillover effects are incomparable. That confirms unequal performance of spatial structures. The W matrix should be built carefully at the beginning of each spatial analysis task.