bluuebunny/crossref_metadata_2025 huggingface dataset:
The Trajectory of Haptoglobin in Haemolysis, Inflammation and Transfusion Reaction
Authors:   Rivers State University, Department of Medical Laboratory Science, Faculty of Science, Ihua Nnenna , Moore-Igwe BW ,   Rivers State University, Department of Medical Laboratory Science, Faculty of Science, Echonwere-Uwikor BE ,   Rivers State University, Department of Medical Laboratory Science, Faculty of Science
Published: April 2024

Introduction: Haptoglobin is an acute-phase α2-glycoprotein produced in the liver with the major biological function of binding free haemoglobin with very high affinity to prevent the loss of iron following hemolysis. Haptoglobin has an anti-inflammatory property and is raised during inflammation whereas, low level is associated with haemolysis. Transfusion is linked with haemolysis thereby increasing the level of free haemoglobin due to anti-haptoglobin and storage effect. Studies have revealed interplay of haptoglobin in haemolysis, inflammation and transfusion reaction although, the underlying mechanism is not well understood. Besides, its utilization as a diagnostic biomarker and therapeutic advantage have not been well explored hence, this study. Method: In this review 20 primary studies from various electronic databases such as Google scholar, Semantic scholar and PubMed were obtained on the basis that they were focused on haptoglobin, haptoglobin in haemolysis, inflammation and transfusion. This was made possible by the use of Boolean function. Results: Haptoglobin, is measured in blood due to its complex formation with hemoglobin, forming a protective non-covalent complex with CD63 as receptor. The finding from this review shows that, haptoglobin plays a crucial role in scavenging surplus hemoglobin, iron and heme in haemolysis with antioxidant function and immunomodulatory effect in transfusion reactions. The concept of the trajectory of haptoglobin explored the multi-dimensional course of this acute phase scavenger protein in the course of clinical conditions of haemolysis, inflammation and transfusion reaction. The review confirmed specific roles of haptoglobin such as physiologic-antioxidant, prognostic, diagnostic biomarker, immunologic and therapeutic. Additionally, an inverse relationship exists between haptoglobin and haemolysis as well as transfusion reaction consequent to hypohaptogloinaemia whereas, direct relationship exists with inflammation resulting to hyperhaptoglobinaemia observed in those clinical conditions respectively. Haptoglobin synthesis is elevated by the liver in response to inflammation, countering oxidative damage and inflammation by neutralizing free hemoglobin. When there is an immunological mismatch, haemolytic transfusion reactions can occur and transfusion of prolonged stored blood potentiate same effect. Conclusion: The role of haptoglobin cannot be overemphasized. Based on the widespread roles and clinical relevance of haptoglobin, it is vital that haptoglobin be utilized
Selected Indicators of Immunothrombosis in Apparently Healthy Nigerian Women of Different Reproductive Status
Authors:   Department of Haematology and Blood Transfusion Science, University of Calabar, Calabar., Akwiwu EC , Esedeke CE ,   Department of Haematology and Blood Transfusion Science, University of Calabar, Calabar., Ndukwe GU ,   Department of Haematology and Blood Transfusion Science, University of Calabar, Calabar., Egbe SB ,   Department of Haematology, University of Calabar Teaching Hospital, Calabar., Abunimye D ,   Department of Haematology, University of Calabar Teaching Hospital, Calabar., Akpotuzor JO ,   Department of Haematology, University of Calabar Teaching Hospital, Calabar.
Published: April 2024

Introduction: Women are considered to be vulnerable with regards to immunothrombotic conditions. Exploring this bidirectional susceptibility across the different female reproductive phases is important for effective maternal healthcare delivery. This study assessed selected indicators of immunothrombosis between premenopausal and postmenopausal women. Methods: Equal numbers of premenopausal and postmenopausal women totaling one hundred were recruited for this comparative study. Blood sample was collected from each participant into appropriate sample bottles. Blood cell counts were carried out by haemocytometry and microscopic blood film reading. Standard manual methods were also employed for prothrombin time, activated partial thromboplastin time and relative plasma viscosity tests, while blood cell ratios were calculated. Results are expressed as Mean ±SD following student t-test analysis of data on SPSS version 22.0. Statistical significance was drawn at a p≤ 0.05. Results: The eosinophils count (0.42±0.31x109/l), monocyte count (0.05±0.05x109/l) and platelets count (150.04±46.88x109/l) were significantly higher in premenopausal women than postmenopausal women (0.29±0.27x109/l, 0.03±0.03x109/l and 132.62±38.37x109/l respectively), while a significantly higher value was observed in the relative plasma viscosity of postmenopausal women (1.74±0.17mPa/s) than the premenopausal women (1.59±0.10mPa/s). The two derived indicators of inflammation (NLR) and thrombosis (PLR) correlated positively in both premenopausal (r=0.397, p=0.004) and postmenopausal (r=0.293, p=0.039) women. Conclusion: Immune and thrombotic parameters are largely comparable in apparently healthy adult females irrespective of their reproductive phase. However, eosinophil, monocyte and platelet counts were observed to be significantly higher in premenopausal women compared to postmenopausal women.
Pre-transfusion compatibility tests in Malagasy sickle cell patients
Authors:   Laboratoire de la Direction Centrale du Service de Santé Militaire, Ampahibe, Batavisoaniatsy EE , Razafinarivo AH ,   Laboratoire de Biologie Médicale, CHU Andohatapenaka, Antananarivo., Tsatoromila FAM ,   Centre Régional de Transfusion Sanguine de la Région d’Analamanga., Randriamanantany ZA ,   Direction de la Transfusion Sanguine, Ministère de la Santé Publique, Antananarivo
Published: April 2024

Introduction: Blood transfusion is a key component of sickle cell disease management. However, iterative transfusions of labile blood products for sickle cell patients increase the risk of anti-erythrocyte alloimmunization. It is usual to perform pre-transfusion compatibility tests in order to check ABO compatibility and to detect the possible existence of irregular antibodies in patients against the donor's antigens. Methods: This is a prospective and descriptive study dealing with pre-transfusion compatibility tests over a 3-month period, from September 2018 to November 2018, at the Regional Blood Transfusion Centre (CRTS) of Analamanga Region, the capital of Madagascar. Results: We included 33 out of 113 patients during the study period. Compatibility test was positive in 21.21%, of all tested samples. Major and minor compatibility tests were positive alone respectively in 6.25% and 12.50%. And both were positive in 3.12%. The self-test was positive in 3.03% with a positive direct antiglobulin test. Positive compatibility tests were more frequent in patients who received more than two transfusions. Compatible blood bag for the patient was found after testing 2 donor pockets in 27.27% of cases, and after testing 3 pockets in 3.03%. Conclusion: Pre-transfusion compatibility tests are essential and have to be performed systematically on each blood bag before any transfusion. They are used to identify the presence of alloantibodies and provide compatible blood products to patients.
Pendampingan Penyusunan Rencana Komunikasi Strategis GPIB Marga Mulya Yogyakarta sebagai Tempat Ibadah Ramah Wisata
Authors: Angretnowati Yuseptia , Fariszy Revta , Rahmawati Keny , Lusye Karolus Meike
Published: April 2024

Melalui kehadiran gereja di ruang publik yang lebih inklusif diharapkan gereja mengalami berbagai konsekuensi positif.  Harapan tersebut tidak hanya mengenai upaya menyuburkan toleransi keberagaman, akan tetapi secara internal dapat berdampak bagi pengembangan sosial, ekonomi, dan budaya bahkan citra positif bagi suatu daerah. Program pengabdian kepada masyarakat ini bertujuan untuk mendampingi GPIB Marga Mulya, Yogyakarta menyusun rencana komunikasi strategis program transformasi gereja menjadi destinasi ramah wisata. Penyusunan rencana komunikasi strategis ini berfokus pada upaya mensistematisasi langkah-langkah komunikatif apa saja yang perlu dilakukan GPIB Marga Mulya. Upaya sistematis tersebut diperlukan untuk mengkoordinasi sumber daya yang dimiliki serta menyusun tindakan komunikatif yang berarti untuk merangkul kembali strakeholder penting, baik itu pemerintah maupun masyarakat untuk menyiapkan gereja ramah wisata. Adapun metode yang digunakan untuk membuat rencana komunikasi strategis GPIB Marga Mulya menuju gereja ramah wisata yang inklusif dan terhubung adalah studi pustaka, wawancara, focus grup discussion, observasi, dan konsultasi pendapat ahli. Setelah berbagai tahap pengumpulan data dilakukan, tim abdimas merumuskan dokumen rencana komunikasi strategis yang akan dimanfaatkan Ketua Majelis Jemaat (KMJ) gereja untuk dikomunikasikan kebijakan ini pada rapat program kegiatan di tingkat majelis jemaat. Selanjutnya hasil dari dokumen rencana strategis ini nantinya juga akan dimanfaatkan untuk menyusun beberapa langkah strategis untuk menjalin komunikasi di level eksternal.
Desa Maju Berbasis Teknologi Informasi Geospasial Melalui Pemetaan Informasi Utilitas Bangunan Lengkap
Authors: Yudanegara Rizky Ahmad , Nurhayati Misfallah , Rahadianto Muhammad Ario Eko , Nugraha Akbar Wahyu , Perdana Redho Surya
Published: April 2024

Dalam menghadapi tantangan era globalisasi, desa berperan krusial dalam mendorong pembangunan yang berkelanjutan. Penelitian ini fokus pada pembangunan berkelanjutan di Desa Karang Anyar, Kecamatan Jati Agung, dengan fokus pada pemetaan informasi utilitas bangunan sebagai alat untuk mendukung perencanaan dan manajemen desa. Studi ini menggunakan metode plotting koordinat sederhana dengan aplikasi Mobile Topographer dan pengumpulan data survei melalui kuesioner untuk mengidentifikasi dan mendokumentasikan lokasi serta fungsi bangunan. Peta yang dihasilkan memvisualisasikan distribusi infrastruktur dan sumber daya desa, termasuk fasilitas umum dan sosial, yang kritis bagi kehidupan komunitas. Hasil pemetaan di Dusun II A menunjukkan potensi untuk pengoptimalan penggunaan lahan dan perbaikan infrastruktur desa. Sosialisasi peta dan pelibatan komunitas dalam pengumpulan data menyediakan wawasan yang lebih dalam tentang kebutuhan dan prioritas desa, memfasilitasi pengambilan keputusan yang didasarkan pada partisipasi masyarakat. Penelitian ini menawarkan bukti pentingnya infrastruktur utilitas dalam pembangunan pedesaan dan menegaskan pentingnya teknologi informasi geospasial dalam pemetaan untuk keberlanjutan dan inovasi desa. Implementasi peta ini diharapkan akan meningkatkan kualitas hidup, mendorong pembangunan ekonomi, dan mendukung kebijakan pembangunan yang berkelanjutan dan responsif di Desa Karang Anyar.
Enfoque sobre la Seguridad Ciudadana
Authors: Moncayo Gallegos Paco
Published: April 2024

To face security program in the urban area, it is necessary to know precisely the phenomena of violence and crime in their different expressions, theoretical approaches and risk factors. It is also important and necessary to analyze the paradigm of citizen security and the main theories, policies and strategies that derive from it and have been proven successful, in order to reach conclusions that are useful for those responsible for this service that, properly exercised, by the public power and society, contribute significantly to the achievement of the objectives of sustainable development.
The Relational Workplace: How Relational Intelligence Grows Diverse, Equitable, and Inclusive Cultures of Connection by Saliha Bava and Mark Greene
Authors: Principe Julio
Published: April 2024

This book by Saliha Bava and Mark Greene is necessary and timely. It invites us to open new spaces for conversation in the family, social and business worlds, using simple language, friendly graphics and inspiring examples.
ปัจจัยที่มีความสัมพันธ์กับผลสัมฤทธิ์ทางการเรียนวิชาวิทยาศาสตร์ของนักเรียนชั้นมัธยมศึกษาปีที่ 3
Authors: อินสำราญ สุธารส , ศรีหาเศษ กมลทิพย์ , ทิพยกุลไพโรจน์ ดารุณี
Published: April 2024

ภูมิหลังและวัตถุประสงค์: การเรียนรู้วิทยาศาสตร์มีความสำคัญต่อนักเรียนเนื่องจากเป็นวิชาที่ช่วยให้นักเรียนมีความคิดสร้างสรรค์ คิดอย่างมีเหตุผล คิดอย่างเป็นระบบและมีแบบแผน สามารถวิเคราะห์ปัญหาหรือสถานการณ์ได้อย่างถี่ถ้วน แต่ทั้งนี้ผลสัมฤทธิ์ทางการเรียนวิทยาศาสตร์มีอิทธิพลมาจากหลายปัจจัย ดังนั้น เพื่อให้ได้สารสนเทศที่นำไปใช้ในการวางแผนจัดการเรียนรู้วิชาวิทยาศาสตร์ และใช้เป็นแนวทางแก้ไขที่จะทำให้ผู้เรียนสามารถพัฒนาผลสัมฤทธิ์ทางเรียนวิชาวิทยาศาสตร์ได้เต็มตามศักยภาพจึงนำมาสู่การวิจัยในครั้งนี้ที่มีวัตถุประสงค์เพื่อ 1) ศึกษาปัจจัยที่มีความสัมพันธ์กับผลสัมฤทธิ์ทางการเรียนวิชาวิทยาศาสตร์ของนักเรียนชั้นมัธยมศึกษาปีที่ 3 และ 2) สร้างสมการทำนายผลสัมฤทธิ์ทางการเรียนวิชาวิทยาศาสตร์ของนักเรียนชั้นมัธยมศึกษาปีที่ 3
ระเบียบวิธีการวิจัย: กลุ่มตัวอย่าง คือนักเรียนชั้นมัธยมศึกษาปีที่ 3 จำนวน 498 คน ซึ่งได้มาจากการสุ่มตัวอย่างแบบหลายขั้นตอน เก็บรวบรวมข้อมูลด้วยแบบสอบถาม วิเคราะห์ข้อมูลโดยใช้การวิเคราะห์การถดถอยพหุ
ผลการวิจัย: 1) สัมประสิทธิ์สหสัมพันธ์ (R) ระหว่างตัวแปรตาม คือ ผลสัมฤทธิ์ทางการเรียนวิชาวิทยาศาสตร์ กับตัวแปรอิสระ คือ เพศ ความรู้พื้นฐานเดิมทางวิทยาศาสตร์ เจตคติทางการเรียนวิทยาศาสตร์ การรับรู้ความสามารถทางวิทยาศาสตร์ การสนับสนุนจากครู การสนับสนุนทางการเรียนวิทยาศาสตร์จากผู้ปกครอง การสนับสนุนจากเพื่อนในการเรียนวิทยาศาสตร์ บรรยากาศในการเรียน ความรับผิดชอบทางการเรียนวิทยาศาสตร์ เท่ากับ 0.92 โดยชุดตัวแปรอิสระสามารถอธิบายความแปรปรวนในตัวแปรตาม (R2) ได้ร้อยละ 84.30 และ 2) ตัวแปรอิสระที่มีความสัมพันธ์กับผลสัมฤทธิ์ทางการเรียนวิชาวิทยาศาสตร์มากที่สุด คือ ความรู้พื้นฐานเดิมทางวิทยาศาสตร์ (b=0.90) รองลงมา คือ เจตคติทางการเรียนวิทยาศาสตร์ (b=0.10) การสนับสนุนจากครู (b=0.07) บรรยากาศในการเรียน (b=0.06) และเพศ (b=0.05) ตามลำดับ โดยสมการทำนายปัจจัยที่มีความสัมพันธ์กับผลสัมฤทธิ์ทางการเรียนวิชาวิทยาศาสตร์ของนักเรียนชั้นมัธยมศึกษาปีที่ 3 โดยการคัดเลือกตัวแปรเข้าสู่สมการ แบบ Enter พบว่า สัมประสิทธิ์ถดถอย (b) ของ เพศ ความรู้พื้นฐานเดิมทางวิทยาศาสตร์ เจตคติทางวิทยาศาสตร์ การสนับสนุนจากครู และบรรยากาศในการเรียน มีนัยสำคัญทางสถิติที่ระดับ .05 สมการทำนายในรูปของสมการคะแนนดิบ คือ
        =   38.54 + 0.96เพศ*+11.58ความรู้พื้นฐานเดิมทางวิทยาศาสตร์*
             +1.65เจตคติทางการเรียนวิทยาศาสตร์*-1.21การสนับสนุนจากครู*–0.90บรรยากาศในการเรียน*
สรุปผล: ผลการวิจัยเผยให้เห็นความสัมพันธ์ที่แข็งแกร่งระหว่างผลสัมฤทธิ์ทางการเรียนทางวิทยาศาสตร์และชุดตัวแปรอิสระที่มีอิทธิพลซึ่งอธิบายส่วนสำคัญของความแปรปรวนโดยรวม ความรู้พื้นฐานทางวิทยาศาสตร์ถือเป็นปัจจัยที่สำคัญที่สุด ตามมาด้วยทัศนคติการเรียนรู้วิทยาศาสตร์เชิงบวก การสนับสนุนจากครู บรรยากาศการเรียนและเพศ การค้นพบนี้ให้ข้อมูลเชิงลึกที่มีคุณค่าเกี่ยวกับปัจจัยกำหนดความสำเร็จทางวิชาการในวิชาวิทยาศาสตร์ของนักเรียนชั้นมัธยมศึกษาปีที่ 3 โดยเน้นถึงความสำคัญของความรู้พื้นฐานและทัศนคติเชิงบวกต่อการเรียนรู้
Integrating Practical Skills Into Multimodal Transportation Education In Indonesia
Authors: Markus Yando  , Larsen Barasa  , Marudut Bernadtua Simanjuntak
Published: April 2024

This research explores the integration of practical skills into multimodal transportation education in Indonesia. Through qualitative analysis of 50 Indonesian cadets, the study examines the balance between theoretical knowledge and practical application, the effectiveness of current educational practices, and recommendations for improvement. The findings reveal a strong consensus among cadets on the importance of practical skills alongside theoretical knowledge. While some practical training is provided, there is a need for more hands-on experiences and industry exposure. Recommendations include revising curricula to include more practical exercises and case studies, strengthening industry partnerships, enhancing instructor skills, integrating soft skills development, and promoting lifelong learning. These recommendations aim to better prepare students for the demands of the transportation industry and enhance their employability. By implementing these recommendations, educational institutions can bridge the gap between theory and practice, ultimately improving the quality and relevance of transportation education in Indonesia.
Analisis Gaya Bahasa Dalam Lirik Lagu “Palestina Tercinta” Karya Shoutul Harokah (Kajian Stilistika)
Authors: Riza Fauzan  , Heri Isnaini
Published: April 2024

The results of this paper examine the use of language styles in the lyrics of the song Palestine Beloved by Shoutul Harokah through stylistic studies. The language of this song's lyrics is an expression of the writer's emotions which is manifested in the form of song lyrics or words. The method used is a qualitative descriptive method. The qualitative descriptive method is research that uses a post-positivist philosophical basis. The aim of this research is to interpret or describe the use of language styles in the lyrics of the song Palestine Beloved. The results of the research that has been carried out show that the use of language styles in this song mostly uses personification language styles, apart from that there is also the use of anadiplosis and synecdoche language styles.
Role of intravenous iron therapy for management of perioperative anaemia: A narrative review
Authors: Thilanka Iddagoda Mayura , Etherton-Beer Christopher , Flicker Leon
Published: April 2024

Anaemia is a frequent problem in surgical patients, and the commonest cause is iron deficiency. There is no agreement among perioperative clinicians on the utility of intravenous (IV) iron therapy in surgical patients. In this study, publications in Medline, Web of Science, and Embase databases, along with major perioperative guidelines up until 2022 were searched using specific key words, and relevant papers that investigated IV iron therapy in the perioperative settings were screened out. Management of perioperative anaemia is comprehensively discussed in major guidelines. However, the diagnosis and management of iron deficiency is not as straightforward as those for anaemia. Iron metabolism is a complex process. IV iron supplementation remains the treatment choice for perioperative iron deficiency; however, it has limited and conflicting evidence of benefits in surgical patients. IV iron replacement, as a part of patient blood management, has shown benefit in perioperative anaemia.
Comparative Analysis of Credit Risk Management Practices: A Study of Domestic and Joint Venture Commercial Banks in Nepal
Authors:   MBA Scholar, Apex College, Mid-Baneshwor, Kathmandu, Nepal, Bist Roshani
Published: April 2024

The capital adequacy ratio, credit to deposit ratio, bank size, leverage ratio, loan loss provision, and non-performing loans were assessed for determining the relationships within domestic and joint venture commercial banks in Nepal. Using secondary data from 10 commercial banks spanning 2006/09 to 2019/20, totaling 140 observations, the study employs descriptive and regression analyses. Data sources include NRB's Banking and Financial Statistics, annual supervision reports, and selected banks' annual reports. HBL has the highest average non-performing loan (2.56%), while NIC Asia has the lowest (0.23%). SCBL exhibits the highest average capital adequacy ratio (15.92%), and SBL leads in credit to deposit ratio (86.85%). EBL tops in bank size (Rs 85,327 million), and MBL in leverage ratio (19.39%). HBL records the highest loan loss provision ratio (1.49%), with NBL at the lowest (0.32%). Descriptive statistics reveal the mean non-performing loan for domestic banks (1.12%), joint venture banks (1.22%), and overall banks (1.17%). The correlation analysis indicates negative correlations between capital adequacy ratio, bank size, credit to deposit ratio, leverage ratio, and loan loss provision with non-performing loans. Regression results underscore the significance of leverage ratio and loan loss provision in impacting non-performing loans for overall banks, while domestic banks find significance only in loan loss provision. Joint venture banks show significance in leverage ratio and loan loss provision. Keywords: Credit risk, Commercial banks, Nepalese banking sector, Leverage ratio, Loan loss provision, Capital adequacy ratio, Descriptive analysis, Regression analysis.
Delivering Agile Marketing Projects: A View from Practice
Authors:   Research Fellow, INPD, Blackthorn House, Appley Bridge, Greater Manchester, United Kingdom, Blair Garry , Betts Peter ,   Consultant, Manchester, United Kingdom, Conway Tony ,   Tutor, Open University, Milton Keynes, United Kingdom, Hyde Margaret ,   Assessor, INPD, Blackthorn House, Appley Bridge, Greater Manchester, United Kingdom, Pagano Rosane ,   Principal Lecturer, Manchester Metropolitan University, Manchester, United Kingdom
Published: April 2024

Successful marketing projects are vital to most organisations to ensure their survival. The paper advocates an 'agile approach' in creating effective marketing initiatives. It underscores the necessity of clearly defined objectives and internal efficiency, addressing power issues for optimal resource allocation. Brand definition, understanding the customer base through profiling, and implementing a differentiated, segmented approach are crucial aspects. The paper recommends data gathering for analysis and leveraging technology to support these projects, all encapsulated within the 'agile approach.' The research methodology involved a survey of literature, complemented by a semi-structured group interview with experienced UK-based marketing professionals. Inductive analysis was applied to the gathered data, extracting principal themes. The outcome of this research proposes a framework for delivering 'Agile marketing projects' based on a project management 'learning' model. This structured approach contributes valuable insights for organizations seeking success in their marketing endeavors. Keywords: Marketing project, Agile approach, SMART objectives, Brand definition, Customer focus, Market segmentation, Leveraging technology
Digital Marketing and Corporate Social Responsibility on Brand Building: A Study of Daraz
Authors:   MBA Scholar, Apex College, Kathmandu, Nepal, Dhakal Shreena , Dhungana Kishore
Published: April 2024

This research aims to investigate the relationship between digital marketing, corporate social responsibility (CSR), and their combined impact on brand building, with a specific focus on Daraz. The research is characterized as quantitative in nature. SPSS software facilitated data analysis, encompassing respondent profiling, descriptive analysis, and correlation and regression calculations. Correlation analysis revealed a significantly positive relationship among all independent variables (social media marketing, promotional activities, social disclosure, environmental disclosure) and the dependent variable (brand building). Hypotheses were formulated to assess the significance of these relationships. Results indicated that promotional activities and environmental disclosure significantly impact brand building. However, multi-collinearity issues hindered the testing of hypotheses related to social media marketing and social disclosure. Despite contributing valuable insights, this research has limitations. The focus on only four variables may overlook other factors influencing brand building. Additionally, the sample size is confined to respondents with internet access, limiting the generalizability of the results to the broader population. These considerations underscore the need for caution when interpreting and applying the findings beyond the scope of this study. Keywords: Digital marketing, Corporate social responsibility, Brand building, Promotional activities, Environmental disclosure.
Total Quality Management and its Relevance in Nepalese Hotel Industry
Authors:   Ph.D. Scholar ,Tribhuvan University, Kathmandu, Nepal, Shah Bijaya Bikram
Published: April 2024

Total Quality Management (TQM) has emerged as a comprehensive organizational management approach, emphasizing continuous improvement to enhance product and service quality. This study aims to investigate the impact of Total Quality Management (TQM) practices on service quality in the hospitality sector of Nepal. Additionally, it seeks to explore how service quality, influenced by TQM practices, affects customer satisfaction in Nepalese hotels. The research focuses on employees in the Nepalese hospitality sector, utilizing a research population of 358 individuals through convenience sampling. Structural Equation Modeling (SEM) is employed as the analytical tool to assess the relationships between TQM practices, service quality, and customer satisfaction. The findings reveal that management support and commitment, quality planning, and continuous improvement significantly contribute to enhancing service quality in hospitality management within the Nepalese context. Furthermore, the study establishes a significant positive influence of service quality on customer satisfaction in Nepalese hotels. This research underscores the relevance of TQM practices in elevating service quality and subsequently impacting customer satisfaction in the burgeoning Nepalese hotel sector. Understanding these dynamics holds strategic importance for industry practitioners and policymakers. Keywords: Hospitality management, Customer satisfaction, Total quality management, Hotel sector, Nepalese.
İESU – İŞLETME VE YÖNETİM BİLİMLERİ FAKÜLTESİ SOSYAL BİLİMLER ARAŞTIRMALARI DERGİSİ (ieSBAD)’NDE YAYINLANAN MAKALELERİN BİBLİYOMETRİK ANALİZİ
Authors: Oran İbrahim Bora , Kantarcı Hakan , Gökmen Ahmet Münir
Published: April 2024

Bu çalışmada, yılda iki kez yayınlanan ve açık erişimli, hakemli, elektronik bir dergi olan İstanbul Esenyurt Üniversitesi İşletme ve Yönetim Bilimler Fakültesi Sosyal Bilimler Araştırmaları Dergisi (ieSBAD)’nin bibliyometrik analizi yapılmaktadır. 2021 yılında kurulan derginin, Haziran-2021 ve Aralık-2023 yılları arasında yayınlanan altı sayıda basılmış makalelerin bibliyometrik açıdan incelenmesi amaçlanmıştır. Bu çalışmada, önce betimleme yöntemi ile bibliyometrik analiz tanıtımı yapılmış, sonra literatürden konu ile ilgili örnekler verilerek bibliyometrik analizin önemi güçlendirilmiş, son olarak elde edilen bulgulara bağlı olarak dergi performansının yükseltilmesine yönelik öneriler geliştirilmesi hedeflenmiştir. Bu çerçevede, belirlenen dönemde dergide yayınlanan makalelerin bibliyometrik kriterlere göre değerlendirilmesi yapılmıştır. Dergide yayınlanan makalelerin yazarlarının mensup olduğu kurumlar arasında başta İstanbul Esenyurt Üniversitesi, Yeni Yüzyıl Üniversitesi ve İstanbul Üniversitesi yer almaktadır. Makalelere yapılan atıflarda, ilk sırada dergiler olmak üzere kitap veya kitap bölümleri ve akademik tezler, internet kaynakları ve bilimsel kongre bildirileri olmak üzere diğer yayınlar bulunmaktadır. Performansı kısa sürede artış trendi gösteren derginin, geleceğe yönelik olarak etki faktörünü yükseltme ve tarandığı endeks düzeyi hedeflerine ulaşmada, en doğru öngörülerin belirlenmesine çalışılmıştır.
Efectos de la neguentropía educativa sobre los desafíos de inclusión en la escuela rural
Authors: Vásquez Rangel Jhovana Alexandra
Published: April 2024

El artículo es producto del ejercicio reflexivo de una investigación que aborda las dinámicas escolares relacionadas con la exclusión y abandono de las trayectorias educativas, con el objetivo de diseñar una ruta metodológica desde una perspectiva multidimensional basada en el pensamiento complejo que permita la culminación de las trayectorias educativas modificando los procesos internos e incorporando estrategias de comprensión de la educación integral. La metodología de tipo mixto parte de la selección de categorías exógenas y endógenas para estudiar los datos históricos e información obtenida con instrumentos cualitativos, de forma que se identificaran los desafíos a que son sometidos un grupo de estudiantes con alta repitencia, desertores, resilientes y probables reprobados en una escuela rural colombiana con altos índices de exclusión. El análisis identifica factores recurrentes en la disminución del progreso académico, así como la necesidad de autorreflexión del papel de profesores y estudiantes. Se concluye con la necesidad de sustitución de las prácticas pasivas – neguentropicas por una visión humanista compleja que aboga por una educación inclusiva que mitigue la desigualdad, destacando el diálogo y la empatía como herramientas efectivas para abordar la problemática de la inclusión escolar.
Chatgpt-Based Didactic Strategies To Improve Students’ English Language Reading And Writing Skills
Authors: Sosa Daza Erick Paúl , Macías Angulo Fernanda del Rocío , Ramírez Lozada Haydeé
Published: April 2024

Teachers have the responsibility to seek new strategies, to innovate, and to select the best technological tools to increase student’s motivation and the proper functioning of learning English. At the present time, artificial intelligence has become a reality; it is no longer something to be dreamt of, but instead something to be used in our daily life. A.I., more specifically, ChatGPT, which is a tool to learn knowledge of all sorts or areas, that can be used by teachers and students to improve their learning, and the different processes that this conveys. The objective of this investigation was to design strategies based on ChatGPT to improve senior high school students’ English language reading and writing skills in Esmeraldas, 2023. The investigation was carried out with a mixed approach, form by a qualitative part and quantitative one. Along with, the methods of analysis and synthesis, hermeneutics, descriptive statistics, inductive, and deductive method. The scope of this research was descriptive, and the design was no experimental. The Population of Study was formed by 60 English teachers from different institutions in Esmeraldas.
Innovative Didactic Activities to Develop Senior High School Students´ English Speaking Skills
Authors: Mosquera Molina Karla Jackeline , Núñez Gutiérrez Irina Katiuska , Ramírez Lozada Haydeé
Published: April 2024

Didactic activities are used by teachers to achieve meaningful learning and to enhance and develop skills in foreign language learners. To overcome the language problems detected at Luis Vargas Torres School in Esmeraldas City, this research aimed as the main objective to analyze the contribution of some innovative didactic activities using technology to develop the students’ communicative speaking skills. The study was designed as a mixed type, with a descriptive approach, and was carried out from December 11, 2023, to January 19, 2024. The sample was composed of 24 students in their third year of Senior High school. The techniques used were a pre-test, a post-test, and a documentary study to design the activities to use during the research. The results of the pre-test showed that 50% of the sample did not pass the test because of problems with fluency, accuracy in pronunciation and grammar, and comprehension; but after the activities using technology, the post-test showed language improvements in most of the students. The technological tools used were the Internet, with worksheet pages and videos, YouTube, and smartphones with the WhatsApp and Messenger applications, all of which respond to TELL (Technology Enhanced Language Learning). It is concluded that the activities designed proved that they cater to social interaction purposes and serve as oral reinforcement of language fluency, accuracy, and course content since they helped to consolidate previous pieces of knowledge that were not fully mastered.
Caracterización de Residuos Plásticos Generados en la Provincia de Orellana-Ecuador
Authors: Peñafiel-Arcos Pedro , Orejuela-Romero Jennifer , Barahona Marcos , Guaicha Lema Diana , Jungal Cárdenas Nilda
Published: April 2024

La generación excesiva de residuos plásticos impide el manejo adecuado de los mismos en cada una de las etapas de la Gestión Integral de los Residuos Sólidos (GIRS) municipales. Este estudio se enfocó en caracterizar los residuos plásticos en los cantones Francisco de Orellana, La Joya de los Sachas y Loreto, provincia de Orellana, utilizando la Norma Técnica Ecuatoriana INEN 2634:2012. Se llevaron a cabo visitas de campo para recopilar datos y se emplearon métodos como la separación manual para la clasificación de los residuos plásticos codificados. Además, se propusieron tres alternativas que fueron evaluadas en términos ambientales, sociales, técnicos, institucionales/legales y económicos. Los resultados revelaron la generación diaria de residuos plásticos codificados por cantones, destacando al Polietileno de tereftalato (PET) como el principal contribuyente con 3322,82 kilogramos, seguido por el Polietileno de alta densidad (HDPE) con 2273 kilogramos y el Polipropileno (PP) con 1758,43 kilogramos. Estos hallazgos subrayan la falta de un control efectivo en el GIRS, resaltando la necesidad de proporcionar condiciones adecuadas para los recicladores base, con el objetivo de fomentar la valorización y aprovechamiento de los residuos plásticos según la propuesta presentada.
Sources of drug information
Authors: Rix Iben , Heerfordt Ida Marie , Cramer Allan , Horwitz Henrik , Olsen Rasmus Huan
Published: April 2024

Modern healthcare requires clinicians to navigate through complex drug treatments. This review offers an overview of sources of drug information which can be used for general medication prescription and for challenging patient populations. Key considerations for pregnant or breastfeeding patients, those with renal impairment, and those with liver dysfunction are discussed. We also touch on adverse drug reactions and drug interactions. Finally, information about services from independent regional drug information centers, that can be used by clinicians, are provided.
Ketersediaan ruang terbuka hijau di Kota Denpasar dan strategi pengelolaannya
Authors: Indrawati Mei , Sudiana A.A. Ketut , Sumantra I.K
Published: April 2024

Green open space (GOS) plays a very important role in realizing a sustainable city and has a balance of ecological and psychological functions for urban communities. Green open space (GOS) can be divided into two categories, namely public GOS and private GOS, but only public GOS can still be controlled directly by the government. Until now, there has been no study regarding the use of public green open spaces in Denpasar City. The aim of this research is to identify the availability of public green open space in Denpasar City, analyze the implications of using public green open space in Denpasar City, and formulate strategies and policies for managing public green open space in Denpasar City. Data collection techniques in this research were interviews and questionnaires. The data analysis techniques in this research are qualitative and quantitative descriptive analysis techniques to determine the availability of public GOS, SWOT analysis for the use of public RTH, and Analytical Hierarchy Process (AHP) to determine management strategies and policies. The availability of public green open space in 2011 was recorded at 2,341.48, or 18.32 percent. The availability of public green open space in 2019 was recorded at 1,572,990 hectares, or 12.49 percent. The difference between 2011 and 2019 was 768,490 ha, or 5.83 percent. The minimum area of public green open space in accordance with the regulations, namely 20 percent, was 1.68 percent in 2011 data and 7.51 percent in 2019 data. The implementation of the utilization of Denpasar City Public Green Open Space (GOS) based on the results of the analysis that has been carried out does not comply with the standards of Minister of Home Affairs Regulation Number 1 of 2007 concerning Arrangement of Green Open Space in Urban Areas and Minister of Public Works Regulation Number 5 of 2008 concerning Guidelines for Providing and Utilizing Green Open Space in Urban Areas. Management still needs to be improved both in terms of handling, security, and maintenance as well as maintaining the availability of existing public open space.
Analisis Minat Belajar Mata Pelajaran IPAS Kelas V SDN Gili Barat
Authors: Revolusi Befa Damai , Mardiyana Isna Ida , Pritasari Ade Cyntia
Published: April 2024

This research aims to determine students' interest in learning in science and science subjects at SDN Gili Barat. This study was conducted at Gili Barat State Elementary School which is located on Jalan Tanjungan, in the Kamal District area, Bangkalan Regency, East Java Province. The research method used is descriptive qualitative. The subjects studied were students in the VA class at SDN Gili Barat with a total of 17 male students and 8 female students. The techniques used are observation, questionnaires and documentation. These VA class students fall into the high class category. The results of the questionnaire stated that Gili Barat Elementary School students liked science and science lessons. The average percentage for each aspect related to preferred activities is 72%, based on conceptual understanding 69%, and based on psychomotor activities 68.8%. Overall, the average response to all aspects measured in the questionnaire shows that students' interest in learning related to science subjects is 69.9%.
Contractual Freedom and Restrictions Included Therein in The Saudi Civil Transactions Law
Authors: Awwad Ahmed Mohammed
Published: April 2024

The Saudi Civil Transactions Law-2023 (SCT Law-2023) was issued with the aim of expanding contractual freedom in a manner that keeps pace with the evolution witnessed by the Kingdom of Saudi Arabia (KSA) in all fields and the required flexibility in concluding contracts. The article aims to assess the status of the SCT Law-2023 on the issue of contractual freedom, by representing its manifestations and restrictions contained therein, by relying on the descriptive and analytical methodologies of the law provisions, and addressing the concept of contractual freedom in comparative law and Islamic Fiqh, where it is concluded that the SCT Law-2023 has a moderate status of the autonomy of the will principle. The main point is that the person’s freedom is to contract or not, the freedom to express his will and the obligation or liability to implement the contract. On the other hand, it does not let the will dictate so it is dominated by the establishment of legal relations, and determine their effects without regard to public interest. This means that the guarantee of contractual freedom does not imply immunity from restrictions required by public interests and stability of dealings.
A Convergent Study on The Impact of a Calligraphy Extracurricular Program on Nursing Students’ Career Decision Making Self-Efficacy and Self-Leadership
Authors: Ko Heesun , Lee Hyunjung
Published: April 2024

This study was a single-group pre-post survey carried out to analyze the effects of a calligraphy extracurricular program on nursing students' career decision making self-efficacy (CDMSE) and self-leadership. The subjects of this study were 230 second-year nursing students. The collected data were analyzed using SPSS WIN 25.0 program for descriptive statistics, paired t-test, one-way ANOVA, and Pearson correlation coefficient. After the calligraphy extracurricular program, CDMSE (t=7.20, p<.001) and self-leadership (t=6.80, p<.001) both advanced, and there was a significant difference in all detailed item. As a result of analyzing CDMSE and self-leadership, it was found that there was a strong correlation both before (r=.81, p<.001) and after (r=.85, p<.001) the program. As a result of this study, the effectiveness of the calligraphy extracurricular program was verified, and it is believed that the desire for aesthetic experience can be satisfied. University education should continue to provide students with a variety of opportunities to improve their capabilities in various ways by organizing a variety of helpful extracurricular programs.
Research on Urban Land Suitability Evaluation Based on GIS—A Case Study of Xi'an City
Authors: Ni Botao , Wei Shiyu
Published: April 2024

The evaluation of urban land suitability plays a crucial role in urban planning and land management. Taking Xi'an City as a case study, this research, based on ArcGIS software, conducted an in-depth study and evaluation of urban land suitability by comprehensively considering factors such as terrain, land use status, and DEM elevation data. By collecting and analyzing a large amount of spatial data, a set of urban land suitability evaluation models was established. With the functionality of ArcGIS software, spatial analysis and data processing were carried out to generate spatial distribution maps of urban land suitability. The research results indicate that land suitability is influenced by various factors, including terrain features, land use status, and elevation. Therefore, when formulating urban planning and land use policies, it is essential to consider these factors comprehensively to promote sustainable urban development and rational resource utilization. In future urban development, it is necessary to combine the influencing factors of urban land to develop more scientifically sound urban planning, aiming to achieve optimized spatial layout of cities and efficient resource utilization.
Agile Human Resources: Memanfaatkan Agilitas untuk Mendorong Kesuksesan Organisasi
Authors: Waruwu Eliyunus
Published: April 2024

Tujuan dari penelitian ini adalah untuk mengevaluasi seberapa efektif implementasi Agile HR dalam perusahaan dan mengidentifikasi faktor-faktor yang berpengaruh terhadap keberhasilannya. Penelitian ini mengadopsi metode kualitatif deskriptif, dengan fokus pada studi literatur untuk melakukan analisis. Agile HR, yang menawarkan pendekatan adaptif dan responsif dalam menghadapi lingkungan bisnis yang dinamis, telah dibuktikan efektif dalam meningkatkan performa organisasi. Keuntungan utama dari Agile HR mencakup peningkatan fleksibilitas, kecepatan, dan kemampuan adaptasi organisasi. Dengan menerapkan prinsip-prinsip Agile dalam fungsi Sumber Daya Manusia, organisasi dapat memperoleh efisiensi, fleksibilitas, dan adaptabilitas yang lebih tinggi, yang penting untuk kesuksesan jangka panjang dalam kompetisi global. Selain itu, Agile HR mengusulkan pendekatan yang lebih fleksibel dalam manajemen kinerja, dengan penekanan pada umpan balik kontinu. Pengembangan kemampuan dan pelatihan karyawan juga merupakan area fokus dalam Agile HR, serta pembangunan budaya kerja yang mendukung kolaborasi dan inovasi sebagai elemen penting.
EBBON OF REIMS AND THE TURNING POINT IN MEDIEVAL ART
Authors:   University of Bucharest, LUNG ECATERINA
Published: April 2024

The whole life of Ebbon, church hierarch, missionary, man of letters and 9th century politician, points without a doubt to a character who was never satisfied with what he had, what he knew or what he achieved. We intend to show to what extent this personal insatisfaction with his lot played a role în finding new ways of visual expression which marked the transition from antique models towards a new, middle ages esthetics.
THE SCHOOL SYSTEM, A FACTOR OF EMANCIPATION, ASSIMILATION AND DISCRIMINATION OF JEWS IN ROMANIA
Authors:   University of Bucharest, GUDIN CRISTINA
Published: April 2024

The present study aims to capture some of the aspects of the relationship between Romanians and Jews, the targeted field being that of education. The school system, an area on which there have been extensive disputes over time, has been used in turn by participants in the training process as a tool for assimilation, discrimination and emancipation. During the period of consolidation of national consciousness, the majority gave shape to the desire to eliminate differences and opened public schools for minorities in order to assimilate them faster. Subsequently, finding shortcomings in the application of the principle of compulsory primary education among Romanians and the overrepresentation of Jews in the public sector, the latter were restricted access to free schooling. The introduction of restrictive provisions for other levels of education was the expression of the radicalization of Romanian society, especially in the twentieth century. On the other hand, these discriminatory measures boosted the opening and development of Jewish schools, and thus the emancipation of the Jewish population.
Unveiling the antimalarial properties of Terminalia ivorensis (A. Chev) stem bark aqueous extract: In vivo efficacy testing and in silico predictions
Authors: Tchatat Tali Mariscal Brice , Madiesse Kemgne Eugenie Aimée , Jiatsa Mbouna Cedric Derick , Tsakem Nangap Marius Jaures , Youbi Kamche Aubin , Hassan Souleyman , Tchouankeu Jean Claude , Boyom Fabrice Fekam
Published: April 2024

Due to the spreading resistance to antimalarial drugs, new therapeutics are urgently needed, preferably with novel modes of action. Extracts from Terminalia ivorensis have previously been shown to possess activity in vitro against multidrug-resistant and drug-sensitive strains of Plasmodium falciparum. However, to the best of our knowledge, no scientific study has been published describing the antimalarial potential of these extracts through in vivo efficacy testing. This study aimed to determine the safety and antimalarial efficacy of the T. ivorensis stem bark aqueous extract (TiH2O) in a mouse model using the OECD 423 protocol and the suppressive and curative murine malaria models, and to predict in silico the pharmacokinetic properties and drug-likeness of two major phytochemical constituents. The in vivo antimalarial efficacy was assessed using the P. berghei NK65-infected mice. The TiH2O treatment impact on biochemical parameters was measured using established standard procedures. The pharmacokinetics prediction was achieved through the pkCSM predictor and Swiss ADME. The TiH2O extract was nontoxic in BALB/c mice at a lethal dose of 50 (LD50) > 2000 mg/kg. The TiH2O extract displayed strong antimalarial efficacy with 100% parasitemia suppression at 200 mg/kg b.w. after 4 days of treatment while its oral administration at 400 mg/kg b.w. in the curative model significantly decreased P. berghei parasitemia by 94.07% with a median efficacy dose (ED50) of 96.80 mg/kg. The administration of TiH2O extract restored the histological parameters disrupted by P. berghei, and the transaminase (ALT and AST) activity, creatinine, and bilirubin levels significantly decreased compared to the negative control mice. In silico explorations showed that the main constituents leucodelphidin (leucodelphinidin) and ellagic acid of the TiH2O extract have drug-like properties, thus indicating that T. ivorensis might constitute a promising source of antimalarial chemical entities with good pharmacokinetics and drug-like properties. The results obtained further corroborated the preliminary in vitro antiplasmodial studies of T. ivorensis stem bark aqueous extract. The metabolome of TiH2O extract should be further profiled in the prospects of characterizing novel natural product scaffolds to support antimalarial drug discovery.
Pérdidas y desperdicios de alimentos en un mercado de la ciudad de Santiago de Cuba
Authors: Rizo Mustelier Miriela , Vuelta Lorenzo Daniel Rafael
Published: April 2024

The issue of food losses is very important in efforts to fight hunger, increase incomes and improve food security in the poorest countries of the world. Food losses affect the food security of the poor, food quality and safety, economic development and the environment. The research was conducted in the state agricultural market “La Vallita”, located on Garzón Avenue in the city of Santiago de Cuba, from September 2018 to April 2019. The purpose of this research is to determine the causes of the losses of agricultural products develop a strategy to reduce losses and waste of food for internal use of the market to raise the standard of service and finally quantify economically the losses and waste of food during the investigation period to implement measures that reduce the same. The losses and waste of food occur mainly due to failures in the productive system.