bluuebunny/crossref_metadata_2025 huggingface dataset:
Spectroscopic and electrochemical investigation of mixed – ligand transition metal complexes with 2N-salicylidine-5-(p-nitrophenyl)-1, 3, 4-thiadiazole and 5, 5’-Me2bipy in aqueous medium
Authors: Srivastava Ashish Kumar , Rai Archana
Published: May 2023

Herein we reported the spectroscopic and electrochemical investigation of four transition metal complexes viz. VO(II), Co(II), Ni(II) and Cu(II) of 2N-salicylidine-5-(p-nitrophenyl)-1, 3, 4-thiadiazole Schiff base ligand (L) and 5,5’-dimethyl-2,2’-bipyridine (Me2bipy) in the aqueous (1: 1: 1 molar ratio) medium. Transition metal complexes were characterized by microanalysis, FT-IR, electronic absorption and mass spectroscopy. Electrochemistry of transition metal complexes was studied in aqueous medium by using cyclic voltammetry (CV) at glassy carbon working electrode (GCE) versus Ag/AgCl. The reduction potential of the VO (II) and Cu (II) becomes more negative with increasing scan rate while Co (II) and Ni (II) positive show easier reduction.
Novel carboxamide and carbohydrazide functionalized pyridopyrimidine derivatives and their anticancer activity
Authors: Dasari Raghu , Gali Srinivas , Vaddiraju Namrata
Published: May 2023

A series of novel carboxamide and carbohydrazide functionalized pyridopyrimidine derivatives was prepared starting from 6-methyl/ethyl-2-oxo-4-(trifluoromethyl)-1,2-dihydropyridine-3-carbonitrile 1. Compound 1 on reaction with sulphuric acid gave compound 2. Compound 2 on reaction with chloroacetamide followed by reaction with EMME coupling and further cyclization gave compound 5. Compound 5 on reaction with hydrazine hydrate produced hydrazide derivatives 6. Compound 6 on reaction with diverse substituted aromatic aldehyde gave Schiff’s base derivatives 7a-j. Ester derivatives 5 on reaction with different aliphatic amine gave carboxamide derivatives 8a-f. All the final 7a-j and 8a-f compounds were evaluated for anti cancer activity against four human cancer cell lines such as HeLa - Cervical cancer (CCL-2), COLO 205- Colon cancer (CCL-222); HepG2- Liver cancer (HB-8065), MCF7 - Breast cancer (HTB-22) and promising compounds 7e, 7h and 7j have been identified.
Composite SiO2:PbCrO4 catalyst as an efficient heterogeneous catalyst for one pot four component synthesis of 1H-pyrazolo [1, 2-b] phthalazine-5, 10-dione derivatives
Authors: Borhade Ashok , Shelke Yogita , Tope Dipak
Published: May 2023

An efficient one pot four component 1H-pyrazolo [1,2-b] phthalazine-5,10-dione derivatives was synthesized by using benzaldehyde, phthalic anhydride, hydrazine hydrate and malononitrile in presence of SiO2 composite PbCrO4 as a catalyst. The composite SiO2:PbCrO4 catalyst was prepared by using hydrothermal process. The XRD, TEM and BET measurement techniques were used for characterization of catalyst. The present method offers several advantages such as use of an inexpensive catalyst, high product yield, short reaction time, mild reaction condition and reusability of the catalyst.
Carbon Dioxide Radical Anion by Photoinduced Equilibration between Formate Salts and [11C, 13C, 14C]CO2 : Application to Carbon Isotope Radiolabeling
Authors: Malandain Augustin , Molins Maxime , Hauwelle Alexandre , Talbot Alex , Loreau Olivier , D'Anfray Timothée , Goutal Sébastien , Tournier Nicolas , Taran Frédéric , Caillé Fabien , Audisio Davide
Published: May 2023

The need for carbon-labeled radiotracers is increasingly higher in drug discovery and development (carbon-14, -, t1/2 = 5730 years) as well as in PET, for in vivo molecular imaging applications (carbon-11, +, t1/2 = 20.4 min). However, the structural diversity of radiotracers is still systematically driven by the narrow available labeled sources and methodologies. In this context, the emergence of carbon dioxide radical anion chemistry might set forth potential unexplored opportunities. Based on a dynamic isotopic equilibration between formate salts and [13C, 14C, 11C]CO2, C-labeled radical anion CO2●- could be accessed under extremely mild conditions within seconds. This methodology was successfully applied to hydro-carboxylation and bis-carboxylation reactions in late-stage carbon isotope labeling of pharmaceutically relevant compounds. The relevance of the method in applied radiochemistry was showcased by the whole-body PET biodistribution profile of [11C]oxaprozin in mouse.
Impact of Hydrogen Concentration for CO2 reduction on PdHx
Authors: Ai Changzhi , Chang Jinhyun , Tygesen Alexander , Vegge Tejs , Hansen Heine Anton
Published: May 2023

Pd hydride has shown much better electrochemical CO2 reduction reaction (CO2RR) performance compared to metal Pd implying that H in the PdHx surface plays a vital role in affecting the performance. Some experiments show phase transformation from metal Pd to PdHx via in-situ X-ray diffraction and electrochemical method. However, studying the stable atomic structures and reaction mechanisms at different H concentrations is experimentally very difficult. Most previous experimental and com- putational studies only focus on the comparison of CO2RR performance of pure metal Pd (0% H concentration) and Pure PdH (100% H concentration). However, there is also no systematical theoretical study about the H concentration effect of PdHx (from 0% to 100%) on CO2RR and the hydrogen evolution reaction (HER), and the atomic structure of the active substoichiometric PdHx catalyst have not been identi- fied. Based on density functional theory (DFT) calculations, active learning cluster expansion equipped with Monte Carlo simulated annealing is carried out to search for stable PdHx(111) surface configurations in this work. We identify 12 stable PdHx(111) configurations from the converged DFT convex hull and theoretically investigate the evolution of the H concentration of the stable structures as a function of applied potential. After automatically finding unique adsorption sites and calculating the binding energies of adsorbates, we analyze their free energy diagram, activity volcano and selectivity toward CO and H2. Finally, we identify the atomic structure of the PdHx phase most likely to produce syngas. It’s activity can be attributed to the fact that H segregation breaks the linear relation between COOH and CO adsorbates.
Enhancing Metabolite Coverage in MALDI-MSI using Laser Post-Ionisation (MALDI-2).
Authors: Mckinnon Jayden , Milioli Heloisa , Purcell Carley , Chaffer Christine , Wadie Bishoy , Alexandrov Theodore , Mitchell Todd , Ellis Shane
Published: May 2023

Matrix-assisted laser desorption/ionisation mass spectrometry imaging (MALDI-MSI) of metabolites can reveal how metabolism is altered throughout heterogeneous tissues. Here MALDI-MSI has been coupled with laser post-ionsiation (MALDI-2) and applied to the MSI of metabolites for the first time. Using mouse kidney and tumour-bearing liver tissue, MALDI-2 significantly improved metabolite coverage and the detection sensitivity of many metabolites. This approach provides a significant advancement for metabolite MSI, enabling the metabolic environment of tissues to be imaged at increased levels of detail.
Reductive Arylation of Nitroarenes with Chloroarenes: Re-ducing Conditions Enable New Reactivity from Palladium Catalysts
Authors: Akana-Schneider Brett , Weix Daniel
Published: May 2023

Palladium-catalyzed C–N bond forming reactions are a key tool in modern synthetic organic chemistry. Despite advances in catalyst design enabling the use of a variety of aryl (pseudo)halides, the neces-sary aniline coupling partner is often synthesized in a discrete reduc-tion step from a nitroarene. An ideal synthetic sequence would avoid the necessity of this step while maintaining the reliable reactivity of palladium catalysis. Herein we describe how reducing conditions enable new chemical steps and reactivity from well-studied palladium catalysts, resulting in a new, useful transformation: the reductive arylation of nitroarenes with chloroarenes to form diarylamines. Mechanistic experiments suggest that under reducing conditions, BrettPhos-palladium complexes catalyze the dual N-arylation of typi-cally inert azoarenes—generated via the in situ reduction of ni-troarenes—via two distinct mechanisms. Initial N-arylation proceeds via a novel association-reductive palladation sequence followed by reductive elimination to yield an intermediate 1,1,2-triarylhydrazine. Arylation of this intermediate by the same catalyst via a traditional amine arylation sequence forms a transient tetraarylhydrazine, un-locking reductive N–N bond cleavage to liberate the desired product. The resulting reaction allows for the synthesis of diarylamines bearing a variety of synthetically valuable functionalities and heteroaryl cores in high yield.
ANALISIS TRANSFORMASI SPASIAL DI WILAYAH URBAN FRINGE KOTA SURAKARTA
Authors: Pamungkas Muhammad Rizal Fernandita , Tamara Anindya Putri
Published: May 2023

Perubahan guna lahan merupakan fenomena yang terjadi akibat dari perkembangan kota yang sangat cepat. Wilayah yang mengalami perubahan guna lahan akibat dari perkembangan kota yakni wilayah pinggiran kota (urban fringe). Kota Surakarta sebagai salah satu pusat aktivitas utama di Provinsi Jawa Tengah mengalami perkembangan kota yang signifikan. Terjadinya perubahan guna lahan di wilayah urban fringe Kota Surakarta memberikan dampak secara struktur keruangan perkotaan Surakarta yakni meningkatnya alih fungsi lahan pertanian menjadi lahan terbangun. Penelitian ini bertujuan untuk mengetahui transformasi spasial di wilayah urban fringe Kota Surakarta. Penelitian ini menggunakan metode penginderaan jauh berdasarkan citra satelit landsat 8 OLI dengan dzetzaka tools dan klasifikasi random forest. Hasil dari penelitian ini menunjukkan dalam jangka waktu 5 tahun (2013-2018) terjadi peningkatan luasan sebesar 3.284 ha lahan terbangun dan hilangnya lahan pertanian seluas 4.004 ha. Proyeksi terhadap data luasan lahan terbangun pada tahun 2013-2018 dapat menunjukkan bahwa pada tahun 2023 diprediksi akan terjadi peningkatan lahan terbangun sebesar 720 ha. Faktor aksesibilitas mempengaruhi transformasi spasial di wilayah urban fringe Kota Surakarta. Perubahan guna lahan paling signifikan terjadi di wilayah sekitar jaringan jalan utama.
Komparasi Karakteristik Gel Dari Daun Cincau Hijau Segar Dengan Gel Dari Bubuk Daun Cincau Hijau (Cyclea Barbata Miers)
Authors: Saputri Dinda Rahmayanti , Rohadi Rohadi , Fitriana Ika
Published: May 2023

Daun cincau hijau yang telah dipanen mudah rusak. Bubuk daun cincau didapatkan dari hasil pengeringan dan pengecilan ukuran. Penelitian ini bertujuan untuk mengetahui perbedaan pada karakteristik fisik (rendemen, sineresis, tekstur, warna, kecepatan pembentukan gel), karakteristik kimia (pH, kadar air, kadar abu, dan serat kasar) dan sensoris gel dari daun cincau hijau segar dengan gel dari bubuk daun cincau hijau (Cyclea barbata Miers). Penelitian dilakukan di Laboratorium Rekayasa Proses Pengolahan Pangan dan Laboratorium Kimia dan Biokimia Pangan Universitas Semarang pada bulan Juni 2022. Rancangan percobaan menggunakan Rancangan Acak Lengkap (RAL), 2 perlakuan, 10 ulangan dan dianalisis dengan independent sample T-Test. Kesimpulan menunjukkan nilai signifikansi kadar air, kadar abu, sineresis, pH, kecepatan pembentukan gel, springiness, sensoris warna maupun spektrofotometri, aroma, rasa dan kekokohan gel dari daun cincau hijau segar dengan gel dari bubuk daun cincau hijau (Cyclea barbata Miers) kurang dari 0,05 (Sig. 2-tailed) yang artinya ada perbedaan yang signifikan. Sedangkan pada rendemen, serat kasar, hardness dan gumminess menunjukan nilai signifikansi lebih dari 0,05 (Sig. 2-tailed) yang artinya tidak terdapat perbedaan yang signifikan.
Multi-material 3D printing for percutaneous surgical drains
Authors:   , Hawkins Isabelle
Published: May 2023

A Percutaneous drain is a medical catheter used by Interventional radiologists to drain abscesses or cysts within the human body. The purpose of drainage is to reduce the need for open surgery, decreasing infections and recovery time. Percutaneous drains were initially designed for irrigation, not drainage; a contributing factor to the current 50% procedural fail rate. Alongside; clogging, kinking and infection.

The focus of the project is to mitigate failure with a fundamental redesign of the percutaneous drain, utilising a multidisciplinary research team from various organisations that work in conjunction to address this Issue.

This thesis, while a component of a more significant study, asks the question, ‘how can design research and multi-material 3D printing, provide innovative insights to improve the clinical performance of percutaneous drains?’

Three elements of the overall drainage procedure are focused on; the efficiency of the drains drainage, the insertion and removal procedure, and simulated anatomy models to provide context to each design. These are explored using multi-material 3D printing as a design tool to investigate new geometries, material combinations and dynamic qualities. Multi-material 3D printing is a design enabler which produces fast and accurate prototypes to explore ideas and communicate intentions to the research team.  

The overall aim of this thesis project is to work alongside healthcare professionals cohesively, to develop novel drainage catheter prototypes. This aim will be achieved by utilising multi-material 3D printing for communication, discussion, rapid prototyping, and development. The primary outputs are innovative designs concepts for percutaneous drains, in the form of CAD files and 3D printed prototypes; while the written thesis documents research outcomes, outputs and process 
The transformation from e-government to e-land administration in Türkiye: A SWOT-based assessment analysis
Authors: PAK Derya Nur Bolat , KIRTILOĞLU Osman Sami , KAYALIK Mert , POLAT Zeynel Abidin
Published: May 2023

The advantage of the developing information and communication technology in terms of both time and cost in service delivery has accelerated the use of these technologies in public administration. With this change, the concept of e-government has taken its place in the literature and has begun to be used in different fields (such as health, safety, tax, education) in many countries. Land management is one of these areas. The Land Registry and Cadastre Directorate and many other public institutions have started to provide many services through e-government within the scope of land management. Thus, the foundations of the transition to e-land administration began to be laid. This study aims to determine the necessary strategies for transition to e-land administration considering the role of the e-government platform in the provision of public services relating to land management in Turkey. Therefore, the current e-service structure related pertaining to land management has been analyzed with the SWOT technique. Thus, the strengths and weaknesses of the existing structure system were revealed. Besides, the opportunities and threats faced by this structure were identified. As a result of the analysis, various suggestions were made for the institutional policies that should be implemented in the transition to e-land administration.
Sztuki plastyczne w naiwnych teoriach uczniów edukacji wczesnoszkolnej
Authors: Sobierańska Dorota , Szyller Aleksandra
Published: May 2023

From the earliest years, thanks to the interpretation of the observed events and on the basis of social and cultural messages, children have been independently building naive theories of the world referring to concepts from the visual arts fi eld. This article presents the results of my own research. The subject of it was based on third-graders’ statements from Warsaw primary schools concerning the interpretation and description of the term ‘visual arts’. Focus interviews were used to collect qualitative data.

According to the research, students’ attempts to defi ne concepts from the visual arts fi eld are very rich and detailed. Most of the naive theories can be realised by the children who have them and can be made present in the form of their verbal and non-verbal statements. Therefore, the youngest children should be involved in discussions on extended cultural topics, of which they can be fullyfl edged participants.
Sztuka mała czy wielka? Refleksje nad twórczością dziecka
Authors: Suświłło Małgorzata
Published: May 2023

This paper primarily aims to present, both theoretically and empirically, the art of children at the early education stage. In the first part of the paper I present theoretical foundations and exemplary studies of the creativity of children aged 4–9. In the empirical part I present results of the study of plastic and literary art of third-graders (age 9–10), undertaken under infl uence of music. In the study the method of observation and analysis of products were applied. The results show that children’s creativity bears features of an intellectual activity and it is saturated with children’s experiences, which is demonstrated by the adequate titles of their literary and plastic art works as well as by the descriptions of the music flow.
Wczesna edukacja i opieka nad dzieckiem jako wyzwanie dla polityki społecznej z perspektywy Unii Europejskiej
Authors: Subocz Elżbieta
Published: May 2023

For two decades we have been observing a lot of interest in the issues of early childhood education and child care in the European Union. Child well-being is seen as an investment in the future of Europe. The article is an attempt to answer the following questions: what are the EU’s views in the field of early childhood education and care? What activities does the European Union take to improve the availability and quality of early childhood education and care for the youngest generation in the Member States? How do the Member States implement the EU’s recommendations?
Theoretical and methodological foundations for the implementation of projects for the interaction of the production sector of the penitentiary system with representatives of the business community
Authors: Malukhov Beslan
Published: May 2023

The article presents the results of a study of the theoretical and methodological foundations for the implementation of projects for the interaction of the production sector of the penal system with representatives of the business community. Analyzed and summarized the specific features of public-private partnership in the production sector of the penitentiary system.
Caracterización agroclimática del cultivo de Agave tequilana Weber en la barranca del Río Santiago
Authors: Tena-Meza Martín Pedro , Navarro-Cerrillo Rafael M. , Villavicencio-García Raymundo , Contreras-Rodriguez Sergio Honorio
Published: May 2023

En sus inicios la producción de tequila utilizó diferentes especies de agaves, con el tiempo el Agave tequilana Weber se consolidó como especie única por presentar mejores características para su cultivo y producción de azúcares. La Barranca del Río Santiago es considerada como el lugar de origen de la planta de Agave tequilana y del proceso de elaboración de la bebida que hoy se conoce con el nombre tequila. A partir de lo declarado por la Organización de las Naciones Unidas para la Educación la Ciencia y la Cultura, el paisaje agavero y las antiguas instalaciones industriales de tequila como patrimonio cultural de la humanidad. La caracterización espacial y temporal de la información climatológica y edáfica disponible para una región en particular permite comprender el tipo de manejo que los agricultores practican sobre sus cultivos, evaluar sus restricciones y posibles efectos en la producción y en el medio ambiente. El objetivo de este trabajo fue conocer las condiciones ambientales bajo las cuales se distribuyen las plantaciones actuales y potenciales del cultivo de A. tequilana en el Cañón del Río Santiago y de manera específica la parte que incluye el paisaje agavero. Se detectó que en la barranca más de 50% de las plantaciones de agave se localizaron en terrenos escarpados sin prácticas de conservación de suelo lo que provoca su pérdida y contaminación con agroquímicos al ecosistema barranqueño, considerado como un atractivo natural a conservar dentro del paisaje agavero.
A MISSIO DEI COMO UMA ABORDAGEM NEOPARADIGMÁTICA DA MISSÃO
Authors: Lucas Felgas Teófilo
Published: May 2023

O presente artigo tem por finalidade conceituar, reflectir e analisar a realidade missionária, na tentativa de compreender sua natureza, propósito e também o seu lugar na Igreja. Perceber em que medida o colapso colonial, a globalização e a pós-modernidade mergulharam a atividade missionária numa crise. Partindo do pressuposto de que o pecado destruiu ou descaracterizou parte da criação, a missão de Deus no mundo vem a ser o antídoto para o processo de restauração. Neste caso, a missão percorre um caminho desafiador, na busca de uma prática missionária bíblica e contextualizada, e assim cooperar com Deus no cumprimento dos seus propósitos eternos.
A MISSIO DEI COMO FUNDAMENTO PRIMORDIAL NO RESGATE DA IDENTIDADE CULTURAL AFRICANA
Authors: Epalanga Abraão Jorge
Published: May 2023

Atualmente, intensifica em África o movimento que se propõe resgatar a identidade cultural africana. O Cristianismo tem sido apresentado como o maior vilão no processo de domínio e ocidentalização do continente e aos poucos as igrejas cristãs africanas ganham o rótulo de serem as principais impulsionadoras para a concretização deste processo e a maior instituição que permite e facilita a neocolonização. Diante desta realidade, o presente artigo visa esclarecer que historicamente o Cristianismo não foi uma religião alienante para nenhum povo ao redor do mundo, entretanto, alguns homens e mulheres com motivações dúbias, foram usados para subjugar e dominar nacionais por conta de suas escolhas e métodos particulares. Com este artigo pretendemos encontrar possibilidades para um caminho melhor que leve ao resgate da identidade cultural africana a partir da compreensão do conceito da missio Dei.
Conceptualización Contemporánea de los Juegos y Deportes Alternativos
Authors: Calle Olga , Antúnez Antonio , Ibáñez Sergio José , Feu Sebastián
Published: May 2023

Este capítulo tiene como objetivo contribuir a la definición actual de los Juegos y Deportes Alternativos. La existencia de una multitud de prácticas que engloba a esta tendencia deportiva, su vertiginosa evolución, así como la ausencia de una definición clara y consensuada de los mismos por parte de los estudios especializados, suscita una problemática en torno a su actual conceptualización. Los Juegos y Deportes Alternativos se han conformado a lo largo del tiempo como un movimiento social que engloba un repertorio variado de actividades físico-deportivas no habituales y en continua transformación donde prima lo lúdico sobre el componente competitivo. Por otra parte, han hecho de la innovación en el uso de materiales una seña de identidad. La idea que sirve de hilo conductor a los Juegos y Deportes Alternativos sería la conjunción de valores que llevan implícitos como la igualdad, la cooperación, diversión, la comunicación, la relación, el juego limpio, etc. Estas prácticas se constituyen como algo más que deportes, se sustentan en principios éticos deseables en una sociedad del futuro, promoviendo nuevas oportunidades educativas de actividad física y de diversión, con la capacidad de transformar las sesiones de Educación Física en actividades verdaderamente innovadoras, respecto a los contenidos, sus posibilidades metodológicas y la propia práctica.
Por uma pedagogia do esporte adaptado: pensando os esportes coletivos de invasão para a pessoa com deficiência
Authors: Venditti Júnior Rubens , Campos Luis Felipe Castelli Correia de , Rocha Cristian Eduardo Luarte , Santos Luiz Gustavo Teixeira Fabricio dos , Pena Luís Gustavo de Souza
Published: May 2023

Em razão do destaque que o esporte e os JEC’s possuem como parte das temáticas desenvolvidas pela EF, este texto tem como objetivo identificar referenciais teóricos que tratem desses conteúdos e do processo de ensino deles, podendo servir como referencial a profissionais de EF que atuam ou atuarão na escola como mediadores do processo de ensino e aprendizagem dos JEC’s no ambiente inclusivo e adaptado ao indivíduo com deficiência. Neste contexto, e a partir das perspectivas apontadas pela PE, que surge dentre as Ciências do Esporte contemporâneas, como alternativa metodológica na abordagem do esporte e dos jogos coletivos de invasão, propomos atividades e esportes adaptados ao público PCD, atuando com base em três referenciais: técnico-tático; socioeducativo e histórico-cultural. Conclui-se que quando adequadamente desenvolvidos em contextos inclusivos, respeitando as individualidades dos alunos e com foco na formação completa dos mesmos, o esporte adaptado e os JEC's contribuem para a evolução dos aspectos físicos, motores, afetivos e sociais de crianças e adolescentes com deficiência.
Why Do We Learn English? Investigating the First Year Students’ Motives to Learn English in Aceh
Authors: Nurbaiti Nurbaiti , Yusuf Yunisrina Qismullah , Muslem Asnawi , Inayah Nurul
Published: May 2023

Integrative and instrumental motivation both play crucial roles in language learning, so it is crucial for teachers to determine which students' motivations are predominant in a classroom. The motivation of first-year students to learn English was examined in this study. It involved 77 first-year students from the Department of English Education at Universitas Syiah Kuala in Banda Aceh, 56 of whom were females and 21 of whom were males. The research tool utilized to gather the data was a questionnaire. The Attitude/Motivation Test Battery served as its model. The acquired data were analyzed using the Statistical Package for Social Science version 23. The results demonstrated that instrumental motivation's mean score (M=44.18) is higher than integrative motivation's (M=43.38). However, there was little difference (at 0.92 percent ). Therefore, it can be said that these students were driven by both integrative and instrumental motivations. Both of these types of motivations are closely related, and they both function as learning objectives with a lot of value. They benefit by way of the students’ learning outcomes as they become more proficient and successful in the target language.
How Ready Can You Be? Profiling Indonesian Teacher’s Preparedness for an Online Teacher Professional Development Program
Authors: Isharyanti Neny , Dewi Finita , Jati Anuncius Gumawang
Published: May 2023

Online teacher professional development has shown benefits in enhancing and improving teacher competences in providing classroom experiences which eventually may improve student academic achievements (de Kramer et. al, 2012). In designing an effective online teacher professional development, a need analysis needs to be conducted to successfully meet the teachers’ needs and design a program that is based on the teachers’ contexts and the complexities of teachers’ teaching practices. The article reports on the results of the need analysis conducted via survey and focus group discussions to 1544 teachers across Indonesia with the aim to design an online teacher professional development delivered via a Massive Online Open Course (MOOC). The results of the need analysis show that the MOOC needs to be designed carefully in terms of the technical requirements, content, and delivery of the MOOC.
Review of resveratrol for the management of hyperlipidemia and survey
Authors: Ayona N. Shelton  , LaNisha T. Potts Alvina C. Okafor  , Bisrat Hailemeskel
Published: May 2023

The goal of this paper is to conduct a literature search to determine the beneficial use of resveratrol in the management of hyperlipidemia. Based on the literature results obtained, a survey questionnaire was developed with the secondary goal of conducting a knowledge and opinion survey among pharmacy students. Data was then analyzed via SPSS software. A total of 45 students participated in the study. There were more females than males (N=27, 64.3%) and the majority were between the ages of 24-26 years old (N=17; 40.5%). More than half lived outside of the Washington, DC, Maryland, and Virginia area (N=27, 57.1%), and have a BA/BS degree (N=34, 81%). The knowledge-based questions were scored, and the average number of correct responses was 58.74%. This reveals that only about half of the respondents were familiar with the beneficial use of resveratrol in lowering serum lipids. However, results also show that although survey participants may be a little familiar with resveratrol, 61.91% of them are least likely to recommend it to family and friends. Some significant values presented during the survey were discussed. Based on this study, it may be advisable to incorporate dietary supplement modules earlier in the didactic portion of the pharmacy curriculum. A larger study that also includes participants from other healthcare professions is necessary.
Part-1: 5X Definitions of hydrogen and renewable energy latex and their importance
Authors: Ravi S. Gonella  , Pratik N. Rao
Published: May 2023

Hydrogen, the emerging zero carbon spectrum fuel that gears residential, commercial and industrial capacities across the world chasing COP 27 to NetZero. It is therefore essential to promulgate the awareness to societies and harness the Greenhouse emissions (GHG) from conventional sources. The hydrogen & renewable energies are breve raged to 40% by 2040 giving protection to Climate & environment that are susceptible to nature. In this paper are highlighted few definitions to beginners who shall revitalize the fuels and technologies of today and tomorrow.
Modification and performance evaluation of the NCAM motorized coconut dehusking machine
Authors: Raheem Olatunji Jimoh  , Mathew Kadiri Bello  , Lois Omolola Abiodun  , Jelili Aremu Oyedokun  , Nurudeen Olabanji Oladipo  , Olusola Adetola Ogunjirin
Published: May 2023

NCAM motorized coconut dehusking machine was tested for its performance. The objective of the test is to optimize the dehusking performance of the machine. Different sizes of coconut fruits were fed into the machine and the time taken for each fruit to be dehusked was noted. A total number of 60 matured Badagry coconuts from Lagos State, Nigeria were dehusked with the machine. The performance evaluation shows that the efficiency of the machine was 90.1% while the average capacity is 122 coconuts per hour. The percentage number of distorted and broken coconuts was 10% and 0% respectively. Hence, the machine is suitable and recommended for small, medium and large scale coconut processors.
Assessment of different brands of diclofenac tablets: An evaluation utilizing uv spectroscopy and disintegration test methods
Authors: Ebiere Dode  , Samuel Jacob Bunu  , Onyinpere Rita Garando
Published: May 2023

Diclofenac is a non-steroidal anti-inflammatory drug (NSAID), that blocks the cyclooxygenase-1 (COX-1) and COX-2 enzymes to inhibit the prostaglandins production. It is available as a salt in the form of potassium, sodium, or epolamine. They are typically administered orally, intravenously, intramuscularly, transdermally, or rectally. Diclofenac is one of the most widely used NSAIDs in Nigeria, and due to the increase in adulterated and subpar medications in the market, it needs to be properly quantified. In this study, the weight uniformity test, disintegration, and ultraviolet (UV) spectroscopy were used to assess five different brands of diclofenac potassium labeled DIC 1 – DIC 5. Analytical balance was used to measure each weight and conduct the weight uniformity test. Using a disintegration apparatus and 0.1 N hydrochloric acid as the medium, a disintegration test was conducted. The UV spectroscopy includes the use of a UV spectrophotometer and the concentration range of 10 – 50 µg/ml was prepared using pure sample and methanol as solvents and scanned between wavelength 220 – 400 nm. The various brands with concentrations of 20 µg/ml were prepared and scanned. The weight uniformity test was passed by all the brands. One brand failed the disintegration test, but one brand did not disintegrate because it was enteric coated. Three brands passed the test. All brands, except for DIC 2, had percentage purity within the stipulated range for chemical analysis.
ASISTENSI MENGAJAR “ENGLISH FOR FUN” DI KECAMATAN LEIHITU, LEIHITU BARAT, DAN LEITIMUR SELATAN
Authors: Tanasale Inggrit O , Retraubun Aditya Samuel , Mantulameten Wenny E
Published: May 2023

The basic and main secondary education are the foundations to teaching English for students. It is, however, inevitable that the geographical factor or a region highly affects the access to sufficient education and infrastructure in terms of teching English. As a response to this necessity, the Teaching Assistance Program, English for Fun, was designed to strengthen the capacities of English teachers. The program focuses on learning vocabularies from descriptive text. The undertaken approach was through Total Physical Response (TPR) methods with songs, games, and pictures. During the implementation at several schools, the students enjoyed these activities. In the end, these activities gave input to the teaching materials made by the team.
“Ilha das Lágrimas”
Authors: RABELO Milena Pereira , BULHÕES Larissa Figueiredo Salmen Seixlack
Published: May 2023

O presente texto analisa o caráter social da construção das identidades de gênero e sexuais, e como o pensamento hegemônico cria padrões para a sociedade e limita as vivências das pessoas. Dentro dessas limitações analisamos a masculinidade hegemônica que determina que para ser um “homem de verdade” é preciso ser e agir dentro de um modelo, e assim, com ajuda de Connell (2013), Finco (2010;2012), Louro (2000), Miskolci (2012), Santos (2020) e Saffioti (2012), buscamos compreender as consequências deste pensamento conservador, pautado no binarismo de gênero masculino/feminino, dentro das instituições de ensino, tendo em vista as crianças e, mais especificamente,  os meninos e suas subjetividades. Por fim, trazemos como possibilidade de prática pedagógica o livro infantil Ilha das Lágrimas, que busca por masculinidades positivas e revela que é possível meninos e homens sentirem e expressarem suas emoções e seus sentimentos.
[Recebido: 30 set. 2021 – Aceito: 28 out. 2021]
Analisis Faktor-Faktor Yang Mempengaruhi Keterlambatan Proyek Apartemen Opus Bay Balmoral Batam
Authors: Iswanda Dyo , Hudori Mahfuz
Published: May 2023

Currently construction projects in Batam City in the field of foundations are increasing rapidly. This is a factor of success and economic growth in Batam City. The city of Batam has shown several towering construction buildings. Tall buildings are very easy to find in Batam City today. The increasing construction of high-rise buildings in Batam City must also be in line with the increase in the success of the project so that construction projects must be completed according to the specified schedule, the right budget, such as making a budget plan, and the expected final results. This study aims to identify the factors that cause delays in the Opus Bay Balmoral project in Batam City. Collecting data in this study used a survey method with a questionnaire instrument and direct interviews with respondents. Data were analyzed using the Relative Score Index method to obtain information on the dominant factors causing delays in the Opus Bay Balmoral development project in Batam City. The research results obtained, there are three factors which indicate that the factors causing the delay in the Opus Bay Balmoral project are: weather factors, design factors, and location factors. These three factors have relative index scores of 0.791, 0.508, and 0.505. Because these three factors have a Relative Index value of > 0.5, with a value for the design factor itself of 0.508, for the weather factor of 0.719 and a location factor of 0.505.
Az el nem ért és az elmért szavazók, a „bizonytalan” nem szavazók. 2022 esete a kétezres évek felől
Authors: Tardos Róbert
Published: May 2023

A 2022-es országgyűlési választás eredményei egy széles szavazóközönség számára sokkszerűen cáfoltak rá a közvélemény-kutatási előrejelzések zöme által keltett várakozásokra. A tanulmány a szerepet játszó mérési problémákat próbálja felfejteni a mintavételi és nem mintavételi hibák egymással összefonódó szövedékéből. Analóg eseteket is felidézve a kétezres évekből, a korabeli kutatások tapasztalatait másodlagos elemzésekkel kiegészítve von le aktuális tanulságokat a 2021–22-es kampányidőszak szituációjára vonatkozóan. Ennek során a véleménynyilvánítás egy háromelemű (perzisztens, alulmondó, felülmondó) tipológiájának a felelevenítése is kiemelt szerepet kap. A torzításoknak a mintalefedéstől a szavazási készség és a pártpreferenciák félrebecsléséig terjedő spektruma alapján a tanulmány egy összegző modellsémával és a feltételezett hibáknak az egyes politikai oldalakat érintő mérlegével zárul, a lehetséges fejlesztési irányokat és azok gazdasági és politikai feltételeit, strukturális korlátait is érintve.
Kesempurnaan Suluk Dan Adab Para Murid
Authors: Valentina Adinda Febriani
Published: May 2023

Here I will discuss about the perfection of mysticism and etiquette of the students. The first thing I will discuss is about Suluk, then in the Suluk chapter I will explain about the meaning of Suluk, the types and then the obligations of students in carrying out the exercises. Then I will explain about "what is the perfection of mysticism?" and lastly I will explain about the manners of the students. Well, the manners of these disciples include: adab to Allah, etiquette to Murshid, adab to oneself and the last adab to relatives or friends who are commonly called ikhwan
Coping Stress Dalam Perspektif Al Qur’an
Authors: Darwati Yuli
Published: May 2023

Dalam kehidupan sehari-hari tentu kita pernah mengalami stres, yang mendorong kita untuk melakukan coping stres supaya kita tidak terjebak dan terpuruk karenanya. Kajian coping stres mendapat perhatian yang besar dalam psikologi. Kajian ini menfokuskan diri pada upaya mengkaji stres dan coping stres dalam perspektif al Qur’an, sebagai rujukan utama umat Islam. Tulisan ini bermaksud untuk mengetahui pandangan Al Qur’an tentang stres, emosi negatif yang menyertai stres, sumber stres, dan mengetahui bagaimana  coping stres menurut al Qur’an, sebagai upaya untuk memperoleh kehidupan yang lebih baik. Penelitian ini dilakukan dengan metode penelitian kualitatif. Sumber data adalah al Qur’an beserta tafsirnya serta hasil telaah para ahli terkait dengan stres dan coping stres. Hasil  penelitian menjukkan bahwa : 1) Al Qur’an memandang stres sebagai cobaan dan ujian dari  Allah SWT ;2) Gejala stres seperti munculnya emosi negatif takut, sedih dan marah dilukiskan Allah dalam surat Al –Ambiya yat 140,  Abasa ayat 33-37, surat Yusuf ayat 84-86, At –Taubah ayat 92, Al-A’raf ayat 150 dan Thoha ayat 92-94. 3) Ada banyak sumber stres yaitu : pertama musibah. Hal ini dijelaskan Allah SWT dalam surat At-taghabun ayat 11, Asy Syura ayat 30 dan Ar-Rum ayat 41. Kedua, Penyakit hati dijelaskan dalam surat Al Baqarah ayat 10, Al-A’raf ayat 179. Ketiga Berprasangka buruk kepada Allah, dijelaskan dalam surat Al Fajr ayat 15-17 dan surat Al Fath ayat 12. Kempat berprasangka buruk kepada orang lain dijelaskan oleh Allah dalam surat Al Hujurat ayat 12.: 4)Allah SWT dalam al Qur’an juga memberikan tuntunan bagaimana mengatasi stres (coping stres), yaitu dengan ikhlas, sabar, zikir, tobat, shalat, dan berpikir positif dan optimis. Pertama, ikhlas dijelaskan dalam Al Qur’an dalam surat At Taubah ayat 91. Kedua, Sabar dijelaskan dalam  Al qur’an asurat Al Baqarah ayat 153 dan Al Baqarah ayat 155-157. Ketiga, zikir dijelaskan dalam Al Qur’an dalam surat Al Baqarah ayat 152, Surat Thoha ayat 130, dan Surat Ar Ra’d ayat 28.  Kempat, Tobat, dijelaskan dalam surat Az-Zumar ayat 53, An Nisa’ ayat 48. Kelima, berpikir positif dan optimis dijelaskan dalam Al qur’an Surat Al-Insyirah ayat 5-6 dan Al Tawbah ayat 51. Keenam shalat, dijelaskan dalam Al Qur’an Surat Al baqarah ayat 153 dan Surat Ghafir ayat 60.
Aplikasi Nilai-Nilai Tasawuf Untuk Meningkatkan Etos Kerja Islami
Authors: Novianti Ika , Fitriah Lailatul
Published: May 2023

Etos kerja merupakan salah satu hal yang fundamental dalam suatu organisasi. Dalam hal ini efektivitas organisasi dapat didorong oleh etos kerja yang kuat dari kinerja kelompok sehingga dalam suatu perusahaan memang diharapkan memiliki karyawan-karyawan yang unggul baik secara hard skill maupun soft skill.  Pada kajian etos kerja islami, ada beberapa hal yang dibutuhkan manusia dalam membentuk etos kerja. Tujuan riset ini adalah mengetahui nilai-nilai tasawuf dalam penerapannya sebagai landasan untuk meningkatkan etos kerja. Metode penelitian menggunakan kualitatif yang bersifat studi pustaka (library research) yang menggunakan buku-buku dan literatur-literatur lainnya sebagai objek yang utama. Pada penelitian kualitatif, perlu dilakukan analisis deskriptif. Metode analisis deskriptif memberikan gambaran dan keterangan yang secara jelas, objektif, sistematis, analitis dan kritis mengenai nilai-nilai etos kerja yang terdapat dalam kitab Ihyā` Ulūmu ad-Dīn. Hasil yang diperoleh bahwa terdapat komponen-komponen dalam tasawuf yang sesuai dalam kajian etos kerja diantaranya adalah al-raja’ (optimisme), istiqomah, sabar, ikhlas, ridho, qana’ah, syukur. Komponen-komponen ini menjadi pondasi utama untuk memahami penerapan konsep etos kerja dalam dunia kerja sehingga manusia tidak hanya bertujuan mencari nafkah tetapi juga mensyukuri nikmat berupa rizqi dari Allah SWT serta berikhtiar tanpa kenal lelah guna mengharap ridho Allah SWT.
Religiusitas Satri Pondok Pesantren Al-Mahrusiyah
Authors: Anfira Rizki Firdausi , Afandi Nur Aziz , Sayekti Fatma Puri
Published: May 2023

Tujuan dalam penelitian ini adalah untuk mengetahui tingkat religiusitas santri di pondok pesantren Al Mahrusiyah Lirboyo Kediri. Penelitian ini adalah penelitian kuantitatif dengan analisis deskriptif. Populasi dari penelitian ini adalah santri dewasa di pondok pesantren Al- Mahrusiyah. Penelitian ini mengguankan metode non-probability sampling dengan teknik sampling purposive atau dengan tidak memberikan peluang yang sama bagi anggota populasi. Jumlah subjek dalam penelitian ini adalah 49 orang. Analisis data dengan menggunakan teknik analisis statistik persentase. Hasil dari penelitian ini menunjukkan bahwa santri Al-Mahrusiyah memiliki tingkat religiusitas yang tinggi dengan jumlah presentase 81,3% dan kategori sedang dengan presentase sebesar 18,36%. Perkembangan religiusitas santri di Pondok Pesantren Al- Al-Mahrusiyah didukung oleh lingkungan santri berasal dan kegiatan-kegiatan pondok baik kegiatan-kegiatan harian, mingguan dan tahunan.
Kajian Struktur Modal Sub Sektor Kosmetik dan Keperluan Rumah Tangga Periode 2015-2020
Authors: Pratiwi Anggi Saktiya , Giovanni Axel
Published: May 2023

Organizations can improve quality by managing their capital structure. The capital structure is the ratio of the level of current liabilities and ownership of capital. This study aims to provide empirical data on the form of capital subsector cosmetics and household indexed in the Indonesia Stock Exchange. This observation uses descriptive statistical methods represented by the calculation of debt-to-equity ratio (DER). Sampling is carried out using purposeful sampling methods protected by six institutional standards. As a result, we found that the calculation of the total liabilities of the enterprise varies with a deviation from the trend of 87.64. Further research is expected to add variable factors that affect the capital structure of the organization.
Kemampuan Financial Technology Dalam Menjangkau UMKM Serta Peluang dan Tantangan Perkembangannya di Indonesia
Authors: Ratundima Alinsia Tabita , Kudu Yonski Umbu , Anakonda Adwan Umbu , Kelen Lusianus Heronimus Sinyo
Published: May 2023

Teknologi keuangan merupakan bentuk inovasi layanan keuangan yang dipadukan dengan menggunakan teknologi. Teknologi keuangan memberikan kemudahan bagi pengguna dalam mengkases salah satunya yaitu pelaku UMKM. Perkembagan teknologi keuangan juga tidak jauh dari peluang dan tantangan yang dihadapi. Tujuan penulisan artikel ini yaitu untuk mengetahui kemampuan teknologi keuangan dalam menjangkau UMKM serta peluang dan tantangan perkembangannya di Indonesia. Sehingga di peroleh bahwa dalam menjangkau mitranya seperti UMKM, teknologi keuangan menggunakan peluang dimana pelaku UMKM sulit dalam memperoleh pengaksesan kreditnya yang di sebabkan oleh minimnya informasi mengenai profil UMKM serta belum terpenuhinya persyaratan manajemen risiko. Adanya hambatan ini membuat peluang bagi teknologi keuangan (fintech) dengan memberikan kemudahan pembiayaan bagi pelaku UMKM. Teknologi keuangan hadir dengan menawarkan model bisnis seperti P2P lending, dompet digital, financial planer dan lainnya. Peluang dan tantangan perkembangannya di Indonesia adalah peluang : Adanya kesempatan yang di berikan OJK bagi pelaku teknologi keuangan untuk mendaftarkan diri di Ojk dan Akses yang mudah dan cepat serta tantangan : Beberapa teknologi keuangan yang belum terdaftar di OJK dan Kurangnya literasi mengenai teknologi keuangan di tengah masyarakat sehingga tingkat kepercayaan masyarakat akan teknologi keuangan masih rendah.
PENGUKURAN KINERJA PEMERINTAH DAERAH DENGAN MENGGUNAKAN PRINSIP VALUE FOR MONEY PADA DINAS PUPR KABUPATEN ACEH BARAT
Authors: Wati Hawala Linda , Putri Cut Mega
Published: May 2023

The problems examined in this study are the Budget Realization Report, reports on changes in Over budget Balance, Balance Sheet, Operational Reports, Changes in Equity Reports, Notes to Financial Statements. In the accountability of this report it was concluded that the PUPR Office of West Aceh District. In its development, the public sector budget system has become a multifunctional policy instrument that is used as a tool to achieve organizational goals. APBD is a regional government financial work plan that will be used as a basis for carrying out development in the region. In preparing, discussing, determining and supervising the implementation of the budget, it is not enough just to look at the size of the budget, but the output must also be produced economically, efficiently and effectively for the development of the region. In this study, the authors wish to analyze the performance of the West Aceh district government by using the principle of value for money which is based on three economic ratios, the ratio of efficiency and ratio of effectiveness. The results of the study show that the performance of the West Aceh District government for the 2020-2021 period as a whole is not good.
17 OBJETIVOS Y UN MAPA. Una aproximación a los ODS desde el patrimonio
Authors: López Sabater Angela , García López de Andújar Vanesa , Portolés Górriz Angel
Published: May 2023

Introducción: Reconocida la importancia de los Objetivos de Desarrollo Sostenible (ODS) para mejorar la vida de las personas y partiendo de una visión holística que incorpora el patrimonio cultural y natural como herramientas clave que contribuyen a su consecución desde la escala territorial, el programa de Extensión Universitaria de la Universidad Jaume I (PEU-UJI) está desarrollando un proyecto centrado en las personas y su labor para poner en valor la cultura, el patrimonio, el arte y el desarrollo social. El proyecto, denominado “17 objetivos y un mapa”, busca aproximar los ODS a las comunidades locales con las que trabaja.
Método: Durante los años 2021 y 2022 se llevó a cabo la fase 1 de este gran proyecto en la que, utilizando herramientas específicamente diseñadas, las comunidades implicadas tomaron conciencia de la importancia de las acciones sostenibles para transformar el futuro. En este proceso se revisaron procesos bajo la perspectiva de los ODS y se compartieron reflexiones, experiencias y buenas prácticas, contribuyendo al aprendizaje mutuo.
Resultados: Los resultados obtenidos en esta primera fase permitieron a los participantes reestructurar algunos aspectos de sus proyectos en beneficio de un futuro más sostenible, crear sinergias, y establecer objetivos específicos relacionados con los ODS, que les permitan medir su impacto de manera más efectiva.
Conclusiones: La fase 1 del proyecto supuso un punto de partida para trabajar de manera pionera en el campo de los ODS desde una perspectiva patrimonial, identificando oportunidades de colaboración entre organizaciones y ampliando el alcance y el impacto de sus actividades.