bluuebunny/crossref_metadata_2025 huggingface dataset:
Model Pembelajaran Rally Coach untuk Meningkatkan Kemampuan Berpikir Analitis, Keterampilan Komunikasi Matematis, dan Penguasaan Konsep Matematika Siswa [RALLY COACH LEARNING MODEL TO IMPROVE STUDENTS' ANALYTICAL THINKING ABILITY, MATHEMATICAL COMMUNICATION SKILLS, AND MASTERY OF MATHEMATICAL CONCEPTS]
Authors: Harianja Joko Krismanto
Published: January 2024

The aim of this research is to determine the differences in analytical thinking, mathematical communication skill and the conceptual mastery between the 7th-grade students who implement the rally coach learning model and those students who do not in the classroom. This research was conducted with nineteen participants for each class. This is a quantitative research using the weak experiment method with a static-group pre-test and post-test design. The instruments used were rubrics and test questions that had been tested for their validity and reliability. The n-gain value obtained was then tested to determine the differences between the two classes using the Mann-Whitney test. Analytical thinking hypothesis test results show the acquisition of the asymp. sig (2-tailed) = 0.005; mathematical communication skill with the asymp. sig (2-tailed) = 0,000; hypothesis testing of the post-test results of the conceptual mastery with the asymp. sig (2-tailed) = 0.002 and the n-gain test obtained the asymp. sig (2-tailed)iT which is less than 0.05. From the results of these tests, it can be concluded that there are differences in the students’ analytical thinking, mathematical communication skill and the conceptual mastery in the control and experimental classes.
Prawnicy tylko dla Żydów. Konsulenci z okręgu Wyższego Sądu Krajowego w Katowicach
Authors: Graczyk Konrad
Published: January 2024

The article is devoted to the issue of consultants, an institution introduced in the Third Reich to represent Jews in legal matters. Some of the Jewish lawyers excluded from the German bar became consultants. The article presents the legal regulation, the reasons for its issuance and its effects. Based on the personal files of three consultants from the district of the Higher National Court in Katowice, the procedure of admitting them and the conditions of their activity were presented. On the basis of court files, the manner in which they conducted their work in criminal cases was analyzed and assessed.

A significant amount of anti-Jewish legislation was passed in Germany after Hitler seized power. Some of the newly introduced regulation also targetted lawyers of Jewish origin, whose professional activities were hindered, and eventually banned. In 1938 Jews were definitively removed from the German bar. At the same time, it was ensured that Jews would be provided with legal assistance and represented by consultants, i.e. lawyers of Jewish origin. There were clearly fewer consultants than Jewish lawyers (several in the districts in which individual higher national courts operated). Their admission was discretionary. According to sparse findings in the literature, consultants were treated adequately by the German courts and were not hindered in their access to court files, contact with clients or the possibility of submitting lawsuits. Three examined cases of consultants from the district of the Higher National Court in Katowice indicate that they enjoyed similar freedoms while performing their functions in the courts, as described in the literature. In their daily activities, however, they had to struggle with difficulties of an administrative or factual nature, which were a manifestation of discrimination and bans against Jews. Based on these three cases, it could be concluded that they were admitted to consular activity due to positive opinions among the population, the judiciary and the Gestapo, as well as their patriotic attitude during the First World War and during the Silesian Uprisings. Their exemplary professional conduct, war decorations, and even injuries sustained on the front of the Great War did not prevent the consultants from sharing the tragic fate of European Jews.
Cranberry supplementation improves physiological markers of performance in trained runners
Authors: Parenteau Francis , Puglia Veronica Furno , Roberts Mary , Comtois Alain Steve , Bergdahl Andreas
Published: January 2024

[Purpose] Cranberries have the highest polyphenol and antioxidant capacity among fruits and vegetables and may protect against exercise-induced free radical production, consequently improving performance. This study aimed to investigate the effect of polyphenol-rich cranberry extract (CE) on time-trial performance and lactate response following exercise.[Methods] A total of 14 trained runners were tested at i) baseline, ii) 2 h following an acute CE dose (0.7 g/kg of body mass), and iii) 4 weeks after daily supplement consumption (0.3 g/kg of body mass). At each time point, runners performed a 1500-m race followed by a 400-m race where the live vastus lateralis oxygenation changes were determined by near-infrared spectroscopy and blood lactate was measured at rest and 1 and 3 min after each trial. The Shapiro-Wilk test and repeated-measures analysis of variance were used to establish significance (P <0.05).[Results] Cranberry supplementation over 28 d improved aerobic performance during the 1500-m time trial, whereas the acute dose had no effect. More specifically, muscle reoxygenation rates were significantly faster after 28 d compared to baseline (P = 0.04; η² = 0.29), and a trend towards slower deoxygenation rate was observed (P = 0.13; η² = 0.20). Chronic CE consumption also buffered the post-exercise lactate response for the 400-m race (P = 0.01; η² = 0.27), while no effects were seen for the longer race.[Conclusion] Our results suggest that cranberry supplementation may have ergogenic effects, as it improves physiological markers of performance during short- and long-distance running.
Probiotics Addition Potential to Increase Body Weight, Feed Consumption and Feed Conversion on Pre-Layer Laying Hens
Authors: Sukmawati Lailatul Jannah  , Mirni Lamid  , Mohammad Sukmanadi  , Mohammad Anam Al Arif  , Sri Hidanah  , Sri Chusniati
Published: January 2024

Probiotics are all forms of microbial cell preparations or components of microbial cells that have a beneficial effect on the health and life of the host. Some feed additives such as the Antibiotic Growth Promoter (AGP) hormone have been banned. Therefore, nowadays, probiotics are often used as additives to replace antibiotics. The probiotics that are widely used are lactic acid bacteria because they can increase the efficiency of digestion and absorption of nutrients. The purpose of this study was to determine the effect of giving probiotics a combination of Bacillus coagulans and Bacillus subtilis with doses of 2 ml, 4 ml, and 6 ml/head/day orally on weight gain, feed consumption, and decreased feed conversion of laying hens. This study was conducted for 2 weeks using pre layer chickens aged 21 weeks to 23 weeks old as many as 24 chickens, randomized into 4 treatments with 6 replications with P0 as control, P1 = 2 ml, P2 = 4 ml, and P3 = 6 ml. The probiotic used is a combination of probiotics Bacillus coagulans and Bacillus subtilis with a concentration of 1x107 CFU/ml in liquid.
Effectiveness of the California Mastitis Test (CMT), Reductase Test, and Alcohol Test for Dairy Cows Subclinical Mastitis Detection
Authors: Eriza Rosalina Rochmah  , Dadik Raharjo  , Sri Hidanah  , Mustofa Helmi Effendi  , Adiana Mutamsari Witaningrum  , Sunaryo Hadi Warsito
Published: January 2024

Mastitis is an inflammation of the mammary glands caused by pathogenic bacteria Mastitis divided into 2 types, clinical mastitis which has symptoms of swelling and changes in the shape of the mammary gland, while subclinical mastitis does not indicate clear symptoms. Subclinical mastitis is a very high case in Indonesia, around 97-98%, while clinical mastitis is 2-3%. Effectiveness of the california mastitis test (CMT), reductase test and alcohol test to detect subclinical mastitis in dairy cattle. The number of samples taken was 60 samples of fresh dairy milk from 15 cattles in Medowo Village as much as 50 ml for each sample. The results showed that the test was very effective in identifying subclinical mastitis in dairy cattle. 15% positive results were obtained for subclinical mastitis using CMT, 10% of the milk quality was not good during the reductase test and 18.33% positive with the alcohol test from a total of 60 samples obtained.
Black Soldier Fly (Hermetia illucens) Maggot Flour as Concentrate Substitution on Broiler Chickens Feed Consumption, Body Weight Gain and Feed Conversion Ratio
Authors: Magdalena Eki Pertiwi  , Sri Hidanah  , Nove Hidajati  , Mirni Lamid  , Widya Paramita Lokapirnasari  , Sunaryo Hadi Warsito
Published: January 2024

This study aims to determine the effect of concentrate substitution with maggot Black Soldier Fly (Hermetia illucens) flour on feed consumption, body weight gain and feed conversion ratio of broiler chickens. This study was an experimental study with a completely randomized design (CRD) with 5 treatment and 4 replications. The material uses broiler chickens age four weeks as many as 20 tails, the feed used is concentrate from the PT. Charoen Pokphand Indonesia, maggot BSF flour, corn and bran. The feed treatment with the addition of maggot BSF flour consisted of P0 (feed without maggot BSF flour), P1 (2% addition of maggot BSF flour), P2 (4% addition of maggot BSF flour), P3 (6% addition of maggot BSF flour), and P4 (8% addition of maggot BSF flour). From the study results obtained the mean and standard deviation of feed consumption, body weight gain and feed conversion of broiler chickens. Analisys of Variance (ANOVA) showed that the subtitution of concentrate with maggot flour from black soldier flies had no significated effect (p>0.05) on the feed consumption, body weight gain and feed conversion ratio of broiler chickens.
Moringa oleifera Flour Fermentation as Feed Additive on Egg Quality in Mojosari Ducks with Different Storage Period
Authors: Rahmaniar Larasati  , Sri Hidanah  , Muchammad Yunus  , Widya Paramita Lokapirnasari  , Emy Koestanti Sabdoningrum  , Mohammad Anam Al Arif
Published: January 2024

Eggs are widely consumed by Indonesian people. High market demand will cause breeders to increase egg productivity and quality. Moringa oleifera leaves addition to the feed could increase egg production. Moringa leaf flour has high crude fiber, so it needs to be fermented. Fermentation aims to reduce crude fiber and increase crude protein. This study aims to determine the effect of using fermented Moringa leaf flour on the egg yolk index of the Haugh Unit and the color of the Mojosari's duck egg yolk with different shelf life. 60 ducks divided into four treatment groups, namely P0 without fermented Moringa leaf flour addition, P1 with 0.5% Moringa leaf flour fermentation, P2 with 1% Moringa leaf flour fermentation, and P3 with 1.5%. Moringa leaf flour fermentation. The results showed that the addition of 1.5% fermented Moringa leaf flour (P3) gave the highest average value for the egg yolk index, Haugh Unit, and egg yolk color with different storage period. Providing fermented Moringa oleifera leaf flour at 1.5% as a feed additive had the highest influence on increasing the egg yolk index, haugh unit value, and egg yolk color of mojosari ducks with different storage period.
Pola Makan, Aktivitas Fisik dan Obesitas pada Pekerja Urban di Indonesia
Authors: Rosmiati Risti , Haryana Nila Reswari , Firmansyah Hardi , Purba Rasita
Published: January 2024

Latar Belakang: Meningkatnya prevalensi obesitas menjadi masalah kesehatan masyarakat yang signifikan di Indonesia, terutama di kalangan pekerja urban yang sering menjalani gaya hidup sedentari dan menerapkan pola makan yang kurang baik.
Tujuan: menganalisis hubungan antara pola makan, tingkat aktivitas fisik, dan obesitas pada pekerja urban di Indonesia.
Metode: Pola makan utama dianalisis menggunakan Principal Component Analysis dari 17 item Food Frequency Questionnaire (FFQ) yang diisi oleh pekerja urban dalam Indonesian Family Life Survey (IFLS) wave 5. Aktivitas fisik dinilai berdasarkan International Physical Activity Questionnaire (IPAQ). Tinggi dan berat badan diukur untuk mengetahui status gizi berdasarkan Indeks Massa Tubuh (IMT). Hubungan antara pola makan, tingkat aktivitas fisik, dan obesitas dianalisis menggunakan analisis regresi logistik, disesuaikan dengan variabel perancu potensial.
Hasil: Sebanyak 10.806 pekerja urban berpartisipasi dalam penelitian ini. Empat pola makan utama diidentifikasi: pola makan tradisional Indonesia yang ditandai dengan konsumsi nasi, sayuran, dan ikan; pola makan Western yang ditandai dengan tingginya asupan makanan olahan dan minuman manis; pola makan modern yang ditandai dengan konsumsi mi instan, gorengan, dan telur; dan pola makan prudent yang ditandai dengan konsumsi buah dan sayuran. Partisipan yang mengikuti pola makan Western berisiko mengalami obesitas yang lebih tinggi, sedangkan mereka yang mengikuti pola makan prudent menunjukkan risiko obesitas yang lebih rendah. Selain itu, aktivitas fisik yang tidak memadai berisiko mengalami obesitas yang lebih tinggi.
Kesimpulan: Penerapan pola makan Western dan aktivitas fisik yang kurang merupakan faktor risiko independen untuk obesitas pada pekerja urban di Indonesia.
The Associations Between Social Media Use with Eating Behavior, Physical Activity, and Nutrition Status among Adolescents in DKI Jakarta
Authors: Amalia Salsabila Nur Idzhni , Octaria Yessi Crosita , Maryusman Taufik , Imrar Iin Fatmawati
Published: January 2024

Background: Increased adolescent social media use can lead to lower physical activity. In addition, the growth of marketing of unhealthy foods and drinks is inevitable. In short, excessive social media use may negatively impact nutrition problems, eating behavior, and physical activities.
Objectives: This study aimed to determine the relationship between patterns of social media use and nutrition status, eating behavior, and physical activity among adolescents in DKI Jakarta.
Methods: The study was cross-sectional and involved 187 students from public high schools in Jakarta. Data was collected using the Food Frequency Questionnaire (FFQ), the International Physical Activity Questionnaire (IPAQ), the use of social media questionnaire, and an anthropometric assessment to measure body mass index for age. The statistical analysis used was the chi-square test.
Results: No significant association were found between the frequency and duration of social media use and nutrition status. The type of exposure to social media content does not show a significant relationship with nutrition status, eating behavior, and physical activity. However, there were significant associations between frequency (p=0.022) and duration (p=0.003) of social media use and eating behavior. Likewise, there was a significant relationship between frequency (p=0.021) and duration (p=0.005) of social media use with physical activity.
Conclusions: Duration and frequency of social media use are associated with riskier eating patterns and lower adolescent physical activity. Therefore, nutrition education in adolescents should also include topics on social media use.
Hubungan Status Gizi, Kebiasaan Sarapan, dan Durasi Tidur Terhadap Produktivitas Pekerja PT. Sejahtera Buana Trada Sunter
Authors: Wiguna Akhsan Fikri , Stefani Megah
Published: January 2024

Latar Belakang: Produktivitas di Indonesia selama 25 tahun terakhir terus mengalami peningkatan sebanyak 3,1% per tahunnya. Sumber daya manusia memiliki peranan yang penting untuk mendukung hal tersebut, yang mana perlu memiliki sumber daya manusia yang bermutu dan berkualitas tinggi.
Tujuan: Tujuan penelitian ini adalah untuk menganalisis hubungan antara status gizi, kebiasaan sarapan dan durasi tidur terhadap produktivitas pekerja
Metode: Subjek penelitian ini berjumlah  39 pekerja dan  dilakukan pada bulan April-Juli  2022. Desain penelitian ini adalah cross sectional dengan penarikan subjek secara purposive sampling.. Kriteria inklusi pada penelitian ini adalah subjek merupakan karyawan PT Sejahtera Buana Trada, subjek berusia 18-55 tahun, bersedia menjadi subjek penelitian, subjek minimal sudah 1 tahun bekerja. Kriteria eksklusi pada subjek dalam penelitian ini adalah subjek yang dalam keadaan puasa untuk menganalisis konsumsi pangan Analisis data menggunakan uji chi-square. Data yang digunakan untuk penelitian ini adalah data primer dan data skunder.
Hasil: Hasil penelitian menunjukkan  mayoritas pekerja di PT. Sejahtera Buana Trada Sunter (71,8%) memiliki produktivitas yang tinggi, hal ini menunjukkan bahwa produktivitas pekerja tergolong  baik.  Terdapat hubungan antara status gizi dengan produktivitas pekerja dengan nilai p=0,002 (p<0,05). Terdapat hubungan antara kebiasaan sarapan dengan produktivitas dengan nilai p=0,003 (p<0,05). Terdapat hubungan antara durasi tidur dengan produktivitas pekerja dengan nilai p=0,004 (p<0,05).
Kesimpulan: Kesimpulan penelitian ini terdapat hubungan antara status gizi, kebiasaan sarapan, dan durasi tidur terhdap produktivitas pekerja PT. Sejahtera Buana Trada Sunter.
Hubungan Kepatuhan Konsumsi TTD, Asupan Zat Gizi, dan Status Gizi Terhadap Kejadian Anemia pada Remaja Putri Di SMPN 1 Gunungsari
Authors: Abby Sekarmirah Octila , Arini Firlia Ayu , Sufyan Dian Luthfiana , Ilmi Ibnu Malkan Bakhrul
Published: January 2024

Latar Belakang: Remaja putri merupakan kelompok yang rentan anemia karena berada pada fase 2nd growth spurt dan mengalami menstruasi setiap bulan. Anemia pada remaja putri dapat memberikan dampak yang merugikan. Peningkatan prevalensi anemia dapat dicegah dan diturunkan dengan suplementasi TTD pada kelompok wanita usia subur (WUS), termasuk remaja putri.
Tujuan: Penelitian ini bertujuan untuk mengetahui hubungan kepatuhan konsumsi TTD, asupan zat gizi, dan status gizi dengan kejadian anemia pada remaja putri di SMPN 1 Gunungsari.
Metode: Penelitian ini menggunakan desain cross sectional. Pengambilan sampel dilakukan dengan teknik stratified random sampling. Data dikumpulkan melalui pemeriksaan Hb, formulir SQ-FFQ, dan pemeriksaan antropometri. Analisis hubungan menggunakan uji Chi-Square dan Fisher’s Exact.
Hasil: Hasil penelitian ini menunjukkan terdapat hubungan antara kepatuhan konsumsi TTD (p = 0,002), asupan protein (p = 0,034), dan zat besi (p = 0,046) dengan kejadian anemia dan tidak terdapat hubungan antara asupan vitamin C (p = 0,139), inhibitor zat besi (p = 0,183), dan status gizi (p = 1,000) dengan kejadian anemia pada remaja putri di SMPN 1 Gunungsari.
Kesimpulan: Kesimpulan dari penelitian ini adalah terdapat hubungan antara kepatuhan konsumsi TTD, asupan protein dan zat besi dengan kejadian anemia, serta tidak ada hubungan antara asupan vitamin C, inhibitor zat besi, dan status gizi dengan kejadian anemia.
 
Kata kunci: Anemia, Asupan Zat Gizi, Remaja Putri, Status Gizi, Tablet Tambah Darah
Indeks Massa Tubuh (IMT) Sebagai Prediktor Hipertensi: Perbandingan Standar WHO dan Asia-Pasifik
Authors: Mulyasari Indri , Afiatna Puji , Maryanto Sugeng , Aryani Aisyah Nur
Published: January 2024

Latar Belakang: IMT yang tinggi berhubungan dengan kenaikan tekanan darah. Klasifikasi IMT dari Asia-Pasifik memiliki cut-off yang lebih rendah untuk overweight dan obesitas dibandingkan standar WHO.
Tujuan: Mengetahui sensitivitas IMT WHO dan Asia-Pasifik dalam memprediksi hipertensi
Metode: Penelitian ini adalah penelitian diagnostik. Populasi penelitian adalah tenaga kerja wanita di perusahaan garmen usia 19-54 tahun. Jumlah sampel 180 orang yang diambil menggunakan teknik simple random sampling. Sensitivitas IMT dianalisis menggunakan Receiver-operating Characteristic (ROC).
Hasil: Sampel yang mengalami gizi lebih berdasar kriteria WHO adalah 30.6% dan 87.8% menurut kriteria Asia-Pasifik. Prevalensi hipertensi sebanyak 85% dan tidak hipertensi 15%. IMT sangat baik untuk memprediksi hipertensi dengan Area Under Curve (AUC) 95.5%. IMT WHO dan Asia-Pasifik berhubungan dengan Kejadian Hipertensi (p<0.001, r=0.278, r= 0.450). IMT Asia-Pasifik memiliki sensitivitas lebih baik dibanding IMT WHO (Se=95.4%, Se=35.9%).
Kesimpulan: IMT Asia-Pasifik lebih sesuai digunakan untuk memprediksi hipertensi dibandingkan IMT WHO pada wanita dewasa Indonesia.
 
Kata kunci: Hipertensi, Indeks Massa Tubuh, Sensitivitas
Hubungan Tingkat Pendidikan dengan Tingkat Ketertarikan Masyarakat terhadap Pelayanan Gizi berbasis Gen di Indonesia
Authors: Listiyana Fani , Aji Arif Sabta , Sari Sintha Dewi Purnama , Irwanti Winda , Wulandari Fatma Annisa , Khouridhiya Mumtaz , Surendran Shelini
Published: January 2024

Latar Belakang: Penyakit Tidak Menular (PTM) merupakan salah satu penyebab kematian di dunia yang terus meningkat setiap tahunnya. Perkembangan ilmu Nutrigenetik dan pelayanan gizi berbasis gen memiliki peran dalam mencegah terjadinya PTM, tetapi masih banyak masyarakat yang tidak mengetahuinya.
Tujuan: Untuk mengidentifikasi hubungan antara tingkat pendidikan dengan tingkat ketertarikan masyarakat terhadap pelayanan gizi berbasis gen di Indonesia.
Metode: Desain penelitian cross-sectional dilakukan secara online menggunakan Qualtrics Survey pada Mei-Juni 2023 di DKI Jakarta, Jawa Barat, Jawa Tengah, Jawa Timur, dan DI Yogyakarta menggunakan teknik cluster sampling. Kuesioner sosiodemografi dan ketertarikan dibuat dan telah diuji validitas dan reliabilitasnya. Data statistik penelitian ini menggunakan uji chi-square.
Hasil: Masyarakat memiliki tingkat ketertarikan yang tinggi terhadap adanya pelayanan gizi berbasisi gen di Indonesia (92,3%). Mayoritas responden setuju bahwa mereka akan menyarankan keluarga mereka untuk melakukan tes nutrigenetik (89,7%). Mereka setuju bahwa pelayanan gizi berbasis gen akan memberikan banyak manfaat bagi mereka (97,5%), serta sebagian besar responden menyatakan bersedia mengeluarkan biaya lebih untuk mendapatkan pelayanan gizi berbasis gen (62,4%). Sebagian besar responden tertarik melakukan tes nutrigenetik untuk mengetahui apakah mereka memiliki risiko penyakit atau tidak (95,9%). Namun, tidak terdapat hubungan antara tingkat pendidikan dengan tingkat ketertarikan masyarakat terhadap pelayanan gizi berbasis gen di Indonesia (p=0,134, OR:0,551, CI=95% (0,27 – 1,11)).
Kesimpulan: Tinggi atau rendahnya pendidikan masyarakat Indonesia tidak berhubungan dengan ketertarikan terhadap pelayanan gizi berbasis gen. Tetapi, masyarakat tertarik dan setuju pelayanan gizi berbasis gen dapat memberikan banyak manfaat terutama untuk pencegahan PTM.
Gambaran Pengetahuan Masyarakat Terhadap Pelayanan Gizi Berbasis Gen Dalam Pencegahan Penyakit Tidak Menular di Indonesia
Authors: Wulandari Fatma Annisa , Aji Arif Sabta , Afifah Effatul , Paramashanti Bunga Astria , Listiyana Fani , Khouridhiya Mumtaz , Surendran Shelini
Published: January 2024

Latar Belakang: Penyakit Tidak Menular (PTM) merupakan masalah kesehatan utama di Indonesia dengan prevalensi yang terus meningkat setiap tahunnya. Perkembangan teknologi seperti layanan gizi berbasis gen dapat menjadi salah satu upaya alternatif dalam pencegahan PTM di masa kini dan masa depan.
Tujuan: Penelitian ini bertujuan untuk menilai gambaran pengetahuan masyarakat Indonesia saat ini tentang pelayanan gizi berbasis gen sebagai pencegahan PTM.
Metode: Penelitian ini merupakan penelitian fenomenologi kualitatif dilakukan di lima provinsi di Indonesia. Wawancara mendalam dilakukan dengan sepuluh informan yang dipilih dengan menggunakan teknik snowball sampling. Penelitian ini berfokus pada tema-tema seperti pengetahuan tentang layanan gizi berbasis gen, pengetahuan genetik, dan pemeriksaan gizi berbasis gen sebagai pencegahan PTM. Analisis tematik dilakukan dengan menggunakan NVivo v.14.
Hasil: Masyarakat memiliki pemahaman baik tentang definisi genetika dan sifat-sifat yang diturunkan. Namun, mereka tidak mengerti tentang terminologi genetika. Mayoritas masyarakat Indonesia memiliki pengetahuan yang kurang tentang pelayanan gizi berbasis gen, tetapi mereka mengakui manfaatnya dalam mendeteksi penyakit dan mengatur pola makan. Mereka juga mengetahui bahwa biaya pemeriksaan ini mahal dan khawatir akan implikasi potensial dari deteksi risiko penyakit. Para peserta memahami bahwa PTM bukanlah penyakit menular dan dapat dicegah melalui intervensi gizi berbasis gen. Minat terhadap layanan gizi berbasis gen cukup tinggi, namun biaya dan ketersediaan fasilitas menjadi hambatan utama. Kesimpulan: Masyarakat Indonesia masih memiliki pengetahuan yang kurang tentang genetika, pelayanan gizi berbasis gen dan pengujian genetik. Namun, mereka memahami bahwa layanan gizi berbasis genetik penting untuk pencegahan dini PTM, menentukan pola diet dan gaya hidup.
Hubungan Asupan Energi, Preferensi Makan, Pengaruh Teman Sebaya, dan Pendidikan Orang Tua dengan Kejadian Gizi Lebih Remaja di Depok
Authors: Nurbaiti Krisanti , Marjan Avliya Quratul , Maryusman Taufik , Octaria Yessi Crosita
Published: January 2024

Latar Belakang: Gizi lebih pada remaja Indonesia merupakan masalah gizi yang meningkat beberapa tahun terakhir dari 7,3% menjadi 13,5%. Faktor-faktor yang berkontribusi pada peningkatan status gizi diantaranya yaitu pola makan, gaya hidup, dan sosial ekonomi. Gizi lebih dapat menimbulkan komplikasi masalah kesehatan seperti penyakit tidak menular.
Tujuan: Menganalisis hubungan asupan energi, preferensi makan, pengaruh teman sebaya, dan pendidikan orang tua dengan kejadian gizi lebih remaja di Depok.
Metode: Penelitian ini menggunakan pendekatan observasional dengan desain cross-sectional. Teknik stratified random sampling digunakan untuk mengumpulkan sampel dari Sekolah Menengah Atas (SMA) terpilih di Depok sebanyak 108 siswa. Status gizi didapatkan dari pengukuran Berat Badan (BB) dan Tinggi Badan (TB) menggunakan Indeks Massa Tubuh berdasarkan Usia (IMT/U), asupan energi dengan wawancara Food Recall 2x24 jam, preferensi makan menggunakan Food and Beverage Preference Questionnaire (FBPQ), pengaruh teman sebaya menggunakan Peer Influence Scale (PIS), dan pendidikan orang tua dengan pengisian kuesioner. Analisis hubungan dilakukan dengan uji Chi-Square dan Fisher Exact.
Hasil: Analisis bivariat menunjukkan asupan energi (p=0,030), preferensi makan (p=0,019), dan pengaruh teman sebaya (p=0,006) terdapat hubungan dengan kejadian gizi lebih. Pendidikan orang tua (ayah, p=0,365; ibu, p=0,103) tidak terdapat hubungan dengan kejadian gizi lebih.
Kesimpulan: Faktor individu remaja memiliki hubungan signifikan dengan kejadian gizi lebih. Remaja perlu memperhatikan intake energi, mengembangkan preferensi makan sehat, dan manfaatkan teman sebaya untuk mengadopsi perilaku makan yang baik agar terhindar dari kejadian gizi lebih.
The Effect of Flexitarian Diet on Waist Circumference and Sagittal Abdominal Diameter (SAD) in Obese Female Students
Authors: Akifah Adzro’ul , Dieny Fillah Fithra , Nuryanto Nuryanto , Noer Etika Ratna , Tsani A. Fahmy Arif
Published: January 2024

Latar Belakang: Obesitas sentral menyebabkan berbagai penyakit. Lemak perut dikaitkan dengan gangguan metabolisme. Intervensi diet yang menargetkan lemak perut dilaporkan memiliki manfaat kesehatan. Pola makan nabati diketahui bermanfaat dalam mengurangi lemak perut.
Tujuan: Penelitian ini bertujuan untuk melihat pengaruh diet flexitarian terhadap lemak perut melalui lingkar pinggang dan diameter sagital perut (SAD).
Metode: Penelitian ini menggunakan quasi eksperimen dengan desain pre-post test control group design. Jumlah subjek penelitian adalah 21 siswi obesitas berusia 19-25 tahun di Semarang. Subyek dipilih dengan menggunakan metode consecutive sampling dan dibagi menjadi kelompok perlakuan dan kelompok kontrol. Kelompok perlakuan diberikan edukasi dan diet fleksibel selama 4 minggu, sedangkan kelompok kontrol diberikan edukasi. Data antropometri diambil sebelum dan sesudah intervensi. Analisis statistik dilakukan dengan uji-t berpasangan, uji-t independen, Mann Whitney, dan ANCOVA.
Hasil: Asupan antar kelompok selama intervensi yang menunjukkan perbedaan statistik adalah energi, lemak, dan serat. SAD antara kelompok perlakuan (-1,2±0,6cm) dan kelompok kontrol (0,2±1,5cm) menunjukkan perbedaan yang bermakna (p=0,010). Tidak ada perbedaan bermakna lingkar pinggang antar kelompok, namun penurunan pada kelompok perlakuan lebih besar (-6,6±5,5cm). Aktivitas fisik tidak mempengaruhi perubahan SAD (p=0,210), sedangkan perlakuan diet mempengaruhi perubahan SAD (p=0,010).
Kesimpulan: Perubahan SAD menunjukkan perbedaan yang signifikan antara kelompok setelah intervensi. Perubahan lingkar pinggang tidak signifikan antar kelompok, namun penurunan lebih besar pada kelompok perlakuan.
Relationship between the Frequency of Formula Feeding and the Use of Milk Bottle Size with the Nutritional Status of Infants Aged 0-24 Months at Puskesmas Merdeka, Bogor City
Authors: Anwar Khoirul , Salsabilla Alya , Syah Muh. Nur Hasan
Published: January 2024

Latar Belakang: Bayi (usia 0-12 bulan) merupakan salah satu fase usia yang rentan terjadi masalah gizi jika  asupan makan bayi yang diberikan kurang tepat.
Tujuan: Menganalisis hubungan antara frekuensi konsumsi susu formula dan penggunaan ukuran botol susu dengan status gizi bayi berusia 0-24 bulan.
Metode: Penelitian dilakukan secara kuantitatif deskriptif dengan desain Cross Sectional Study. Responden penelitian adalah ibu yang memiliki anak berusia 0-24 bulan yang bersedia dan aktif datang ke posyandu. Responden berjumlah 66 orang yang selanjutnya dibagi menjadi kelompok yang memberikan susu formula dengan frekuensi 1-4 botol dan >4 botol per hari serta penggunaan ukuran botol ≤180 ml dan >180 ml per hari. Responden dipilih secara purposive sampling. Uji statistic menggunakan mann withney untuk megetahui perbedaan kedua kelompok sampel. Selain itu, data juga diuji dengan menggunakan uji rank spearman untuk uji hubungan.
Hasil: Terdapat hubungan signifikan antara frekuensi pemberian susu formula dengan indeks pertumbuhan BB/PB atau BB/TB (P=0,005; R=0,338). Terdapat hubungan signifikan antara penggunaan ukuran botol susu formula dengan indeks pertumbuhan PB/U atau TB/U (P=0,021; R=0,283), BB/PB atau BB/TB (P=0,023; R=0,280) serta IMT/U (P=0,004; R=0,353).
Kesimpulan: Terdapat perbedaan status gizi pada penggunaan ukuran botol susu 1-4 botol per hari dan >4 botol per hari. Status Gizi bayi dengan Indeks pertumbuhan BB/PB atau BB/TB menunjukkan hasil yang signifikan mengarah ke obesitas pada bayi yang diberikan susu formula >4 botol per hari.
Kata kunci: Bayi Usia 0-24 bulan, Perilaku Ibu, Status Gizi, Susu Formula
Peran Corporate Social Responsibility PT Pertamina Patra Niaga Fuel Terminal Boyolali dalam Pemberdayaan Keluarga Nelayan Waduk Kedung Omboh
Authors: Alfiyansyah Afiarta Akbar
Published: January 2024

Program Berdikari di Fuel Terminal Boyolali telah dilaksanakan sejak tahun 2017 dengan sasaran ibu-ibu rumah tangga dan para pemuda-pemudi untuk dapat memiliki usaha. Pada tahun 2022 ini meluaskan program ke Desa Sarimulyo Kecamatan Kemusu dengan sasaran perempuan nelayan waduk kedungombo. Permasalahan masyarakat nelayan yakni minimnya pengetahuan dalam pengelolaan ikan, sehingga ikan hasil tangkap langsung dijual ke tengkulak yang mengakibatkan harga ikan tidak menentu. Hal ini kemudian membuat PT Pertamina Patra Niaga Fuel Terminal Boyolali melakukan pendampingan dengan membentuk kelompok perempuan nelayan jajanan iwak (JAWAK). Program ini sebagai wujud tanggung jawab perusahaan dengan melakukan pemberdayaan perempuan nelayan guna meningkatkan kapasitas dan memandirikan keluarga nelayan dengan mengurangi tingkat ketergantungan ekonomi terhadap tengkulak. Penelitian ini bertujuan untuk melihat peran program CSR dalam memberdayakan perempuan nelayan. Metode yang digunakan dalam penelitian ini yakni kualitatif dengan pengambilan data secara purposive sampling kepada aktor kunci, melakukan observasi dan studi literasi. Hasil penelitian ini yakni terdapat peran yang sangat besar dari kegiatan CSR FT Boyolali dalam mengurangi tingkat ketergantungan keluarga nelayan waduk dengan tengkulak. Peran tersebut meningkatkan nilai ekonomi ikan dengan kelompok Jawak  menghasilkan produk turunan seperti ikan asap, kripik ikan dan lainnya.

Kata kunci: Peran, CSR, Nelayan, Waduk Kedungomboh, Tengkulak
Systematic review on the centrocentral anastomosis technique for the surgical treatment of traumatic neuromas
Authors: de Ruiter Godard C.W.
Published: January 2024

Aim: Centrocentral anastomosis (CCA) can be applied in the treatment of painful neuromas, by connecting nerve ends or fascicles after neuroma resection, with or without an interposed nerve graft. While this technique was developed directly after the introduction of microsurgical techniques, it is currently not frequently applied in neuroma treatment.

Methods: In this article, the literature on CCA was systematically reviewed, both for clinical and experimental studies. Specific attention was paid to the different surgical techniques, potential applications, and pathophysiologic mechanisms that might explain how CCA can prevent neuroma formation.

Results: A total of 15 articles were found on this subject, 11 clinical and 4 experimental studies. In clinical studies, CCA was mostly applied for neuroma treatment following amputation of fingers and lower limbs. In experimental studies, different combinations of nerve connections and grafts were investigated in the rat sciatic nerve model. Pain reduction in the clinical studies overall was good to excellent, but only in two studies control groups were used. Results from experimental studies showed that the use of an interposed graft was beneficial by entrapment of axons inside the graft.

Conclusion: Although CCA has shown promising results for neuroma treatment, there are only a few case series to date, one cohort and one randomized study, and in the latter two, no graft was used. More research is needed to investigate the outcome of CCA, especially for the option of an interposed nerve graft. This investigation should involve comparisons with alternative techniques, utilization of standardized outcome measures, and, preferably, inclusion of longer follow-up periods.
Current understanding of the genetics of thoracic aortic disease
Authors: Levy Lauren E. , Zak Megan , Glotzbach Jason P.
Published: January 2024

Thoracic aortic dissection is a feared, highly lethal condition most commonly developing from aneurysmal dilation of the thoracic aorta. Elective prophylactic replacement of thoracic aortic aneurysms dramatically mitigates this risk. However, diagnosis of a thoracic aortic aneurysm can be challenging. Thoracic aortic disease - horacic aortic aneurysm and dissection (TAAD) - can be sporadic or heritable. Patients with syndromic heritable TAAD present with classic phenotype and clinical features correlating to their disease. In contrast, patients with non-syndromic heritable disease are harder to diagnose due to their lack of defining uniform phenotypes. Recent advances in genomics have begun to elucidate the genetic underpinnings of non-syndromic TAAD (ns-TAAD) for better understanding this complex disease and improve diagnosis and management. Herein, we review the foundation of knowledge in ns-TAAD heritability and key research studies identifying gene mutations in vascular smooth muscle cells, the extracellular matrix, and TGF-beta signaling present in ns-TAAD. We summarize the current guidelines for the diagnosis, screening, and surgical management of ns-TAAD including recommendations for genetic testing of high-risk individuals. Finally, we highlight areas of future research that will continue to advance our understanding of the complex genetic and epigenetic factors in TAAD.
Characterisation of Intra-tumoural Subregions Heterogeneity and Tumour Grade Prediction using CT Scan Images: An In-depth Radiomics Features Machine Learning Analysis of Clear Cell Renal Cell Carcinoma
Authors: Alhussaini Abeer J. , Steele J. Douglas , Jawli Adel , Nabi Ghulam
Published: January 2024

Background: Renal cancers are among the top ten causes of cancer specific mortality; of which the ccRCC subtype is responsible for most of the cases. Grading of ccRCC is important in determining the tumour aggressiveness and clinical management. Objectives: To predict the WHO/ISUP grade of ccRCC pre-operatively and characterise the heterogeneity of tumour subregions using radiomics and ML models including comparison with pre-operative biopsy determined grading in a subgroup. Methods: Data was obtained from multiple institutions across two countries from 391 patients with pathologically proven ccRCC. For analysis, the data were separated into 4 cohorts. Cohort 1 and 2 were data from the respective institutions from the two countries, cohort 3 was the combined data and cohort 4 data was a subset of cohort 1 where both biopsy and subsequent histology from resection (partial or total nephrectomy) was available. 3D image segmentation was done to derive a voxel of interest (VOI) mask. Radiomic features were then extracted from the contrast enhanced images and the data normalised. Correlation coefficients and XGBoost model were used to reduce the dimensionality of the features. Thereafter, 11 ML algorithms were implemented for the purpose of predicting the grade of ccRCC and characterising heterogeneity of subregions in the tumours; Results: For cohort 1, 50% tumor core and 25% tumor periphery exhibited best performance with an average AUC of 77.91% and 78.64% respectively. 50% tumor core had the highest performance in cohort 2 and cohort 3 with an average AUC of 87.64% and 76.91% respectively. Cohort 4 with 25% periphery showed an AUC of 95% and 80% for grade prediction using internal and external validation respectively while biopsy histology had an AUC of 31% for the prediction with final grade of resection histology as a reference standard; Conclusion: Radiomic signatures combined with ML have the potential to predict the WHO/ISUP grade of ccRCC with superior performance compared to pre-operative biopsy. Moreover, tumour subregions contain useful information that should be analysed independently when determining tumour grade. It is therefore possible to distinguish the grade of ccRCC pre-operatively to improve patient care and management.
Multi-Spectral Band-Aware Generation of Satellite Images Across Domains Using Generative Adversarial Networks and Contrastive Learning
Authors: Mahara Arpan , Rishe Naphtali
Published: January 2024

Generative models have recently gained popularity in Remote Sensing, offering substantial benefits for interpreting and utilizing satellite imagery across diverse applications such as climate monitoring, urban planning, and wildfire detection. These models are particularly adept at addressing the challenges posed by satellite images, which often exhibit domain variability due to seasonal changes, sensor characteristics, and especially variations in spectral bands. Such variability can significantly impact model performance across various tasks. In response to these challenges, our work introduces a novel approach that harnesses the capabilities of Generative Adversarial Networks (GANs), augmented with Contrastive Learning, to generate target domain images that account for multi-spectral band variations effectively. By maximizing mutual information between corresponding patches and leveraging the power of GANs, our model aims to generate realistic-looking images across different multi-spectral domains. We present a comparative analysis of our model against other well-established generative models, demonstrating its efficacy in generating high-quality satellite images while effectively managing domain variations inherent to multi-spectral diversity.
Investigation of Molecular Compounds in Kumquat (Fortunella spp.) Peel via Raman Spectroscopy
Authors: Yildirim Humeyra , Tulum Isil , Erol Ayse , Sarcan Fahrettin
Published: January 2024

In this study, Raman spectroscopy is employed to investigate the chemical compounds of kumquat peels and compared that of orange. Kumquat is a citrus fruit belonging to the genus Fortunella in family Rutaceae. It is observed that kumquat peel has 3 main Raman active characteristic vibration modes specified to carotenoids, which is dominated by β-carotene at 1007, 1158 and 1526 cm-1, as it is well known for orange. The carotenoid distribution within the cross-section of kumquat is also investigated. The carotenoid-related Raman vibration modes are relatively stronger on the peel of kumquat, which is an important finding especially for the fruits that can be eaten with its peel. Our results pave the way to take an attention for the importance of kumquat as being a fruit that can be grown up in different climates compared to orange, which grow in warm climates.
Comparison of LIRADS 5 Image Guided Core Biopsy Derived From Formalin Fixed and Frozen Tissue Cores for Radiogenomics and Radioproteomics Analysis in Well, Moderate and Poorly Differentiated Hepatocellular Carcinoma
Authors: Simonian Margaret , Lu David sk , Whitelegge Julian P , Cohn Whitaker , Ahuja Preeti , Hsu William , Raman Steven
Published: January 2024

The aim of this pilot study is to evaluate and compare the quality of the genomics and proteomics data obtained from paired formalin fixed paraffin embedded (FFPE) and frozen (FF) tissue percutaneous core biopsies of LIRADS 5 hepatocellular carcinoma (HCC) of varying histological grade. The preliminary data identified differentially expressed proteins and genes in poor, moderate and well differentiated HCC biopsies, with a greater efficacy in fresh frozen samples.
Effect of Fermentation Time and Blending Ratio on Microbial Dynamics, Nutritional Quality and Sensory Acceptability of Shameta: A Traditional Cereal-Based Fermented Porridge for Lactating Mothers in Ethiopia
Authors: Kitessa Daniel Asfaw , Bacha Ketema , Tola Yetenayet B. , Murimi Mary
Published: January 2024

Ethiopia is one of the countries with the highest level of malnourishment of lactating mothers in sub-Saharan Africa. However, different communities produced different foods solely for lactating mothers. "Shameta" is one of the cereal-based fermented cultural foods exclusively produced for lactating mothers with the perception that it would support the health, strength, and recovery of mothers. This study investigated the effects of fermentation time and blending ratio on the nutritional quality of "Shameta." Three levels of blending ratio of ingredients (Maize-Barley-Fava bean) and three levels of fermentation times were laid down in a completely randomized design (CRD). The study showed that lactic acid bacteria were the dominant group, followed by yeasts. Notably, the ingredient formulation ratio of Maize-Barley-Fava bean (81:5:5) in all fermentation times (8, 10, and 12 days) results in the highest LAB dominance with the highest crude fat (13.23 g/100g) content. However, the highest crude protein (16.56 g/100g) and mineral contents were observed in a ratio mix of 66:10:15 fermented for 12 days. The nutritional quality of culturally prepared Shameta can be improved by optimizing fermentation time and ingredient compositions for better recovery, strength, and health of lactating mothers.
Hypoxia-Induced Pulmonary Injury—Adrenergic Blockade Attenuates Nitrosative Stress and Inflammation but Not Pulmonary Edema
Authors: Riha Isabel , Salameh Aida , Hoschke Annekathrin , Raffort Coralie , Koedel Julia , Rassler Beate
Published: January 2024

Hypoxia can induce pulmonary edema (PE) and inflammation. Furthermore, hypoxia depresses left ventricular (LV) inotropy despite sympathetic activation. Here, we investigated the role of nitrosative stress and cardiovascular dysfunction in hypoxic lung injury. Additionally, we studied effects of adrenergic blockade (AB) on hypoxia-induced pulmonary injury. Eighty-six female rats were exposed for 72 h to normoxia or normobaric hypoxia and received infusions with NaCl, prazosin, propranolol or prazosin-propranolol combination. We evaluated hemodynamic function and performed histological and immunohistochemical analyses of the lung. Hypoxia significantly depressed LV but not right ventricular (RV) inotropic and lusitropic functions. AB significantly decreased LV function both in normoxia and hypoxia. AB effects on RV were weaker. Hypoxic rats showed signs of moderate PE and inflammation. This was accompanied by elevated levels of tumor necrosis factor (TNF)  and nitrotyrosine, a marker of nitrosative stress in the lungs. In hypoxia, all types of AB significantly reduced both TNF and nitrotyrosine to normoxic levels. However, AB did not attenuate PE. Results suggest that hypoxia-induced sympathetic activation contributes to inflammation and nitrosative stress in the lungs but not to PE. We suggest that AB in hypoxia aggravates hypoxia-induced inotropic LV dysfunction and backlog into pulmonary circulation, thus promoting PE.
Transpiration Dynamics of Esparto Grass (Stipa tenacissima L.) in Semi-Arid Mediterranean Climate: Unraveling the Impacts of Soil Water, Pine Competence, and Bush Maturity
Authors: Pérez-Anta Iván , Rubio Eva , López-Serrano Francisco Ramón , Garcés Diego , Andrés Manuela , Picazo Marta , Chebbi Wafa , Arquero Rocío , García-Morote Francisco Antonio
Published: January 2024

Stipa tenacissima (S. tenacissima), or esparto, is a perennial tussock grass that coexists with Pinus halepensis (P. halepensis) in semi-arid mediterranean woodlands. This research was carried out to explore diurnal transpiration at leaf level in esparto grass under different levels of pine-esparto competition and in contrasting environmental conditions of soil water. The measurements were spanned from the summer 2020 to spring 2021. The relationship between transpiration and competence was conducted in open and closed P. halepensis stands and taken into account the type of leave (green, senescent) and the maturity of the esparto grass. We observed a higher control of transpiration in green leaves, and correlations between transpiration and soil water were noted exclusively in this type of leaf. Our results substantiated a significant impact of pine competitors on transpiration of esparto grass, particularly during seasons characterized by high water-demand scenarios: the summer drought period and the commencement of the growing and flowering period (spring). Furthermore, our findings confirmed a greater response to transpiration in mature bushes compared to young ones under severe water stress, denoting higher adaptation to drought as esparto ages. Our results may have important implications for the dynamics and management of these semi-arid mixed woodlands, as well as the planning of reforestation programs aimed at restoring esparto grass steppes.
Parenchymal Cavitations in Pulmonary Tuberculosis: Comparison between Lung Ultrasound, Chest X-ray and Computed Tomography
Authors: Cozzi Diletta , Bartolucci Maurizio , Giannelli Federico , Cavigli Edoardo , Campolmi Irene , Rinaldi Francesca , Miele Vittorio
Published: January 2024

This article aims to detect lung cavitations using lung ultrasound (LUS) in a cohort of patients with pulmonary tuberculosis (TB) and correlate the findings with chest computed tomography (CT) and chest x-ray (CXR) to obtain LUS diagnostic sensitivity. Patients with suspected TB were enrolled after being evaluated with CXR and chest CT. A blinded radiologist performed LUS within 3 days after the admission at the Infectious Diseases Department. Finally, 82 patients were enrolled in the study. BAL confirmed TB in 58/82 (71%). Chest CT showed pulmonary cavitations in 38/82 (43.6%; 32 TB patients and 6 non-TB ones), LUS in 15/82 (18.3%; 11 TB patients and 4 non-TB ones) and CXR in 27/82 (33%; 23 TB patients and 4 non-TB ones). Patients with multiple cavitations were 12 detected at CT and only 1 at LUS. LUS sensitivity was 39.5%, specificity 100%, PPV 100%, NPV 65.7%. CXR sensitivity was 68.4% and specificity 97.8%. No false positive cases were found. LUS sensitivity is rather low as many cavitated consolidations do not reach the pleural surface. Aerated cavitations could be detected with LUS with relative confidence, highlighting a thin air-crescent sign towards the pleural surface within a hypoechoic area of consolidation, easily distinguishable from dynamic or static air-bronchogram.