bluuebunny/crossref_metadata_2025 huggingface dataset:
A Review of Black Soldier Fly (Hermetia illucens) as a Potential Alternative Protein Source in Broiler Diets
Authors: Ahmed Ibrar , İnal Fatma , Riaz Roshan , Ahsan Umair , Kuter Eren , Ali Usman
Published: February 2023

Since per capita global meat utilization is predicted to increase to 40% from 2019 to 2050, global use of cultivable land in livestock, poultry, and feed production is 30%. Use of alternative protein sources as animal feed can be a solution to minimize cropland usage in conventional feed production. Commonly used protein sources in animal diets like soybean meal and fish meal are facing challenges of high demand, but the current production might not fulfill their dire need. To overcome this issue, the discovery of alternative protein sources is the need of the hour, insect meals like black soldier fly (BSF) are one of these alternative protein sources. These flies are non-infectious, bite-less, can convert the variant types of organic waste (food wastes, animal and human excreta) proficiently into rich profile biomass with reduced harmful bacteria count and do not serve as a vector in disease transmission. Based on the substrate used, the BSF larvae protein, fat and ash contents vary from 37 to 63%, 7 to 39% and 9 to 28% on dry matter basis, respectively. Previous studies have reported using BSF and its by-products as alternative protein sources in broiler diets with partial or complete replacement of conventional protein sources. In this review, a brief introduction to insect meal, BSF origin, life cycle, nutritional profile, influences on growth performance, carcass characteristics, fatty acid profile of meat, biochemical properties of blood, gut morphology and microbiota of the caecum along with its influence on laying performance of layers has been discussed in detail. Studies have concluded the partial replacement of conventional protein sources with BSF is possible, whereas complete replacement may cause poor performance due to reduced digestibility up to 62% attributable to chitin content (9.6%). Further studies to corroborate the effect of dietary BSF on growth performance, carcass characteristics, fatty acid profile of meat, and gut morphology and caecum microbiota are required to standardize the inclusion levels in feeds for higher performance of poultry.
Rumen protozoa population and carbohydrate-digesting enzymes in sheep fed a diet supplemented with hydrolysable tannins
Authors: Majewska Małgorzata Paulina , Miltko Renata , Bełżecki Grzegorz , Kędzierska Aneta , Kowalik Barbara
Published: February 2023

The aim of the study was to compare the effect of adding different sources of hydrolysable tannins to the sheep diet on protozoa population and carbohydrate digestion in the rumen. The study was performed in 3 Polish Lowland ewes fistulated to the rumen in a 3 × 3 Latin square design. Control sheep (CON) received (g/d): meadow hay (600), barley meal (300), soybean meal (100) and vitamin-mineral premix (20). Sheep from the experimental groups were additionally administered 12.6 g/kg DM oak bark extract (OAK) and 3.91 g/kg DM tannic acid (TAN ). The net consumption of tannins was approx. 0.4% DM for both additives. Regarding the count of protozoa, a significant interaction between diet and sampling time was documented for all ciliates (P<0.01), with a significant effect of both factors when considered separately. Experimental diets reduced the number of total protozoa and Entodinium spp. (before feeding, 2 and 4 h after feeding; P<0.01), while increasing the abundance of Isotricha spp. population (4 h after feeding; P<0.01) in the rumen. Interestingly, the count of Ophryoscolex spp. after feeding the TAN diet increased before feeding and 2 h after feeding in comparison to the CON and OAK groups, respectively, and subsequently decreased compared to the CON diet (4 and 8 h after feeding, P<0.01). A significant interaction between the diet and sampling time was observed for xylanolytic activity (P<0.01) in the rumen, with a significant effect of sampling time, which decreased its activity in CON (after feeding) and OAK sheep (2 h after feeding; P<0.01). For amylolytic activity (P<0.10), there was a trend towards a significant interaction between experimental factors, with a significant effect on both diet and sampling time. Detailed analysis showed that the TAN diet significantly reduced amylolytic activity 2 h after feeding compared to the CON group (P<0.05). In conclusion, the TAN diet significantly reduced the number of total protozoa and Entodinium spp., which consequently reduced amylolytic activity in the rumen, without any significant effect on pH and carbohydrate fermentation in the rumen.
Frequency of ABH secretor status: a cross-sectional study in Lagos, Southwestern Nigeria
Authors: Fakorede Samson T. , Salami Sulaimon A. , Adekoya Khalid O. , Oboh Bola
Published: February 2023

The mucosa contains soluble antigens of the ABO blood group system. Secretor status as a trait has been linked to a variety of clinical diseases and is determined by the individual’s fucosyltransferase 2 (FUT2) allele. The distribution of secretor status in relation to ABO blood group phenotypes varies from region to region, with medicolegal significance. There is a dearth of information on the secretor status of the studied population. The aim of the present study was to evaluate the secretor status of the ABH in a Nigerian population. To achieve this, fresh saliva samples (~5 ml) were collected from 325 (181 males and 144 females) apparently healthy individuals in the urban city of Lagos. Secretor status was determined by haemagglutination inhibition test with the saliva samples of participants. Results showed that 85% of the participants were secretors and 15% were non-secretors with no statistically significant differences (p>0.05) between male and female gender. The frequencies of the Secretor, Se and Non-secretor, se genes were 0.543 and 0.457, respectively while the frequencies of the SeSe, Sese, and sese genotypes were 0.294, 0.496, and 0.209, respectively. The participants’ ABO blood group distributions were 65.5% group O, 16.6% group A, 15.1% group B, and 2.8% group AB. The incidence of secretors across blood group was 89% in group O, 85% in A, 79% in B and 67% in AB. However, there were no statistically significant variations in secretor status and ABO blood group (p>0.05). In conclusion, the study shows that there are more secretors than non-secretors, and the ability to secrete the ABH antigens are independent of ABO blood of individuals.
O cuidado profissional no contexto do HIV/AIDS em diferentes regiões do Brasil
Authors: Cristina de Oliveira Denize , Munhen de Pontes Ana Paula , Yta Machado Yndira , Frutuoso Antunes Rômulo , Laporte Almeida de Souza Camila , Spindola Thelma , Benemérita Alves Vilela Alba , Maria da Silva Abrão Fatima
Published: February 2023

Objetivo: Discutir as representações sociais do cuidado profissional às pessoas que vivem com HIV entre profissionais de saúde no Brasil. Materiais e Método: Estudo exploratório, descritivo, com abordagem quanti-qualitativa, fundamentado na Teoria das Representações Sociais, proposta por Serge Moscovici, utilizando a abordagem estrutural. Estudo realizado com 648 profissionais de saúde que atuavam em serviços de referência para Aids, nas cinco regiões brasileiras: região norte, nordeste, centro oeste, sudeste e sul. A coleta de dados foi realizada com questionário de evocações livres ao termo indutor “Cuidado à pessoa com HIV/Aids” e de caracterização sociodemográfica. A análise dos dados foi realizada com estatística descritiva e análise estrutural prototípica das representações sociais. Resultados: No grupo total de profissionais observou-se uma representação social positiva, que concebe o cuidado à pessoa com HIV a partir de práticas educativas, de humanização, orientadas tecnicamente e de apoio afetivas, institucionalmente inseridas e presentes no conhecimento científico sobre o cuidado à saúde. As representações sociais do cuidado de saúde nas diversas regiões geográficas brasileiras estão voltadas para a promoção da adesão ao tratamento, através da educação em saúde e de estratégias relacionais, impactando na morbimortalidade deste grupo. Conclusão: Os cognemas constitutivos dessa representação expressam as dimensões conceitual, afetiva e atitudinal reveladoras do cuidado humanizado e tecnicamente orientado, sem especificidade ao HIV em nível central.
Pengaruh Leverage, Profitabilitas, dan Kebijakan Dividen terhadap Nilai Perusahaan
Authors: Tandrio Gleen , Handoyo Sarwo Edy
Published: February 2023

Penelitian ini bertujuan untuk menjelaskan pengaruh dari leverage, profitabilitas, dan kebijakan dividen terhadap nilai perusahaan perbankan yang terdaftar di Bursa Efek Indonesia pada tahun 2017-2020. Jumlah sampel yang digunakan dalam penelitian ini adalah sebanyak 12 perusahaan, yang ditentukan menggunakan purposive sampling. Data dianalisis menggunakan model fixed effect dengan menggunakan perangkat lunak Eviews 12. Hasil penelitian ini menunjukkan bahwa leverage (DER) berpengaruh secara negatif dan signifikan terhadap nilai perusahaan, profitabilitas (ROE) berpengaruh secara positif dan signifikan terhadap nilai perusahaan, dan kebijakan dividen (DPR) berpengaruh secara positif namun tidak signifikan terhadap nilai perusahaan.

 

This study aims to explain the effect of leverage, profitability, and dividend policy on banking companies listed on Indonesia Stock Exchange in 2017-2020. The number of samples used in this study were 12 companies, which were determined using purposive sampling. Data analysis uses a fixed effect model using Eviews 12 software. The results of this study indicate that leverage (DER) has a negative and a significant effect on firm value, profitability (ROE) has a positive and significant effect on firm value, and dividend policy (DPR) has a positive but not significant effect on firm value.
Pengaruh Orientasi Kewirausahaan dan Inovasi terhadap Kinerja Usaha pada UMKM Batik Semarang
Authors: Kusnadi Felix Reinaldo , Utama Louis
Published: February 2023

Penelitian ini dilakukan untuk mengetahui apakah Orientasi Kewirausahaan dan Inovasi memiliki pengaruh terhadap Kinerja Usaha pada UMKM industri batik. Populasi dalam penelitian ini adalah UMKM industri batik di Semarang, Jawa Tengah. Jumlah sampel dalam penelitian ini adalah sebanyak 110 pemilik UMKM batik di Semarang, Jawa Tengah dan semua data sampel yang diperoleh dinyatakan valid dan reliabel. Teknik pengambilan sampel yang digunakan yaitu non probability sampling dengan metode pengambilan sampel purposive sampling. Pengumpulan data yang dilakukan adalah dengan menggunakan kuesioner berskala Likert. Desain penelitian yang diterapkan dalam penelitian adalah desain konklusif kausal. Metode analisis data dilakukan dengan melalui program Software Smart Partial Least Square (PLS) versi 3.0. Secara keseluruhan hasil dari penelitian ini adalah Orientasi Kewirausahaan memiliki pengaruh terhadap Kinerja Usaha pada UMKM industri batik di Semarang dan Inovasi memiliki pengaruh terhadap Kinerja Usaha pada UMKM industri batik di Semarang.

 

This research was conducted to find out whether Entrepreneurial Orientation and Innovation has an influence on Business Performance in the batik industry MSMEs. The population in this study is the batik industry MSMEs in Semarang, Central Java. The number of samples in this study were 110 batik MSME owners in Semarang, Central Java and all sample data obtained were declared valid and reliable. The sampling technique used is non-probability sampling with purposive sampling method. Data collection was carried out using a Likert scale questionnaire. The research design applied in the study is a causal conclusive design. The data analysis method was carried out using the Smart Partial Least Square (PLS) Software version 3.0. The results of this study are that Entrepreneurial Orientation has an influence on Business Performance in the batik industry MSMEs in Semarang and Innovation has an influence on Business Performance in the batik industry MSMEs in Semarang.
Factors Influencing Firm Value Case Study: In Manufacturing Companies
Authors: Handayani Umi Hanik , Andriasari Widi Savitri
Published: February 2023

Abstrak Penelitian ini bertujuan untuk menguji pengaruh Struktur Modal, Kinerja Keuangan dan Laba Bersih terhadap nilai perusahaan pada perusahaan manufaktur indeks saham syariah yang terdaftar di Bursa Efek Indonesia. Data Penelitian bersumber dari laporan keuangan perusahaan manufaktur indeks saham syariah yang terdaftar di Bursa Efek Indonesia. Sampel dalam pengujian sebanyak 31 perusahaan dengan menggunakan teknik purposive sampling. Penelitian ini menggunakan teknik analisis regresi linier berganda. Hasil pengujian menunjukkan bahwa struktur modal dan kinerja keuangan berpengaruh positif dan signifikan terhadap nilai perusahaan. Sedangkan laba bersih berpengaruh positif namun tidak signifikan terhadap nilai perusahaan. Secara simultan terdapat pengaruh semua variabel bebas terhadap Nilai Perusahaan manufaktur indeks saham syariah yang terdaftar di Bursa Efek Indonesia Abstract This study aims to examine the effect of Capital Structure, Financial Performance and Net Income on firm value in manufacturing companies listed on the Indonesian Stock Exchange. The research data is sourced from the financial reports of manufacturing companies listed on the Indonesian Stock Exchange. The samples in the test were 31 companies using a purposive sampling technique.This study uses multiple linear regression analysis techniques. The test results show that capital structure and financial performance have a positive and significant effect on firm value. While net income has a positive but not significant effect on firm value. Simultaneously, there is the influence of all independent variables on the value of manufacturing companies in the Islamic stock index listed on the Indonesia Stock Exchange
Effectiveness of Islamic Economic Contribution Post Pandemic
Authors: Lubis Delima Sari , Zein Aliman Syahuri , Mutiah Nur , Siregar Nurul Qosimah , Nabila Walidah Izzah
Published: February 2023

Abstrak Pandemi virus corona-19 memberikan dampak negatif bagi perekonomian global, termasuk Indonesia. Pertumbuhan ekonomi Indonesia diprediksi minus 0,4%. Penerapan physical distancing telah mengurangi aktivitas ekonomi masyarakat sehingga terjadi penurunan penawaran agregat yang berdampak pada penurunan produksi. Dari sisi penawaran dan permintaan, Work From Home berdampak pada penurunan Permintaan Agregat, sehingga produksi menurun. Hal itu akan semakin merusak kelancaran mekanisme pasar. Ketika sektor ekonomi riil terganggu, krisis akan dirasakan secara merata oleh seluruh lapisan masyarakat, sehingga berdampak pada sektor keuangan. Kajian ini bertujuan untuk mengidentifikasi kontribusi filantropi ekonomi Islam yang tepat dalam menghadapi pandemi. Penelitian ini merupakan penelitian kualitatif dengan menggunakan studi literatur. Riset menyimpulkan bahwa ada beberapa kontribusi filantropi ekonomi Islam yang efektif dalam mengatasi pandemi. Kontribusi tersebut pertama, optimalisasi penerapan keuangan sosial (penyaluran dana ZIS, pengembangan infrastruktur berbasis wakaf, pembinaan dan pendampingan UMKM melalui pinjaman qardhulhasan). Kedua, pengembangan teknologi keuangan syariah bagi pelaku pasar online agar sesuai dengan ketentuan syariah Abstract The corona virus pandemic-19 had a negative impact on the global economy, including Indonesia. Indonesia's economic growth is predicted to be minus 0.4%. The application of physical distancing has reduced people's economic activity, resulting in a decrease in aggregate supply, which has an impact on decreasing production. From a supply and demand perspective, Work From Home results in a decrease in the Aggregate Demand, so that production decreases. This study aims to identify the appropriate contribution of Islamic economic philanthropy in the face of a pandemic. The research concludes that there are several contributions from Islamic economic philanthropy that are effective in overcoming the pandemic. These contributions are first, optimization of the application of social finance (distribution of ZIS funds, development of waqf-based infrastructure, guidance and assistance to SMME through qardhulhasan loans). Second, the development of Islamic financial technology for online market players to comply with sharia regulations.
Lexicographic Epic: To the 100th Anniversary of the Institute of Linguistic Research of the Russian Academy of Sciences
Authors: Nikitin O. V.
Published: February 2023

The report analyzes the anniversary collection of scientific articles “History, theory and Practice of Academic Lexicography” dedicated to the 100th anniversary of the establishment of the Institute of Linguistic Research of the Russian Academy of Sciences and the 90th anniversary of the Lexicographic sector. The work determines the place of scentific problems in the history of linguistics, and notes the main directions of the Institute’s activities and their connection with the cultural and historical tradition of A. A. Shakhmatov, V. M. Istrin, L. V. Shcherba, etc. The article indicates priority works of St. Petersburg school of academic lexicography and their role in the formation of the tradition of Russian science of the 20th – 21st centuries, and emphasizes the relevance of modern developments of scientists in the field of historical lexicography, the creation of explanatory and dialect dictionaries. The review highlights the actualization of the theory and practice of dictionary activity for the creation of multi-volume reference sources, new card files, and typological research in the field of lexicography as an obvious advantage of the collection of articles.
Horse Gait Terms in Turkic Languages of Siberia (Compared to Mongolic Languages)
Authors: Diachkovskiy F. N. , Tazranova A. R. , Bayarsaykhan B. , Trofimova S. M. , Popova N. I.
Published: February 2023

Purpose. Russian and foreign linguists studied the influence of Turkic languages on the grammatical and lexical composition of Mongolic languages. Material from monuments and modern living languages of Siberia shed light on the role of the early Turkic and Mongolic language in the development of the modern linguistic landscape of the region, specifying its place in the Altai linguistic family from a cultural perspective. Horse is a sacred animal for all Turkic and Mongolic speaking nomads that take an important place in their economy and culture, with all its characteristics being featured in the lexicon of the languages under comparison. Researchers also examined a wide range of Mongolian words reflecting various sex- and age-specific terms for livestock and its color as well as keeping and pasturing practices, pasture characteristics, livestock economy, etc. The lexicon characterizing horse movement in Turkic and Mongolic languages has not been the subject of comparative analysis in modern Turkic studies. Thus, the paper describes and analyzes the lexico-semantic group of words that represent the terms for the pattern of natural movement of horse in Turkic and Mongolic languages.

Results. To achieve the research objectives we used the synchronous descriptive, comparative, contrastive-typological, and where possible comparative-historical methods. The study defined the structure and semantics of linguistic units, revealing considerably more similarities than differences in the plane of expression in both Turkic languages of Siberia and Mongolic layers of vocabulary.

Conclusion. Yakut demonstrates both the Turkic and Mongolic layers, which is characteristic of all languages under comparison. Also, there are later borrowings from Buryat, e.g. the verbs denoting ‘amble’.
Concerning the Landscape in A. P. Chekhov’s Short Story “Ionych”
Authors: Dolzhenkov P. N. , Jin Tianhao
Published: February 2023

Purpose. The article discusses the connection between the landscape descriptions in the short story and its content.

Results. The landscapes, together with Delvig’s elegy and the reference to Pisemsky’s novel A Thousand Souls, partly anticipate the content of the story and give the reader an opportunity to expect beforehand that Ionych’s love for Kotik will fade, and the protagonist of the story will end on a downward slope. The contraposition of the sublime, the poetic and the prosaic everyday matters is the common theme of the whole short story Ionych. This contraposition is set up in the beginning of the story in the description of the garden. The landscape descriptions also echo the themes of the story and introduce some of them. The inscription over the cemetery gate introduces the theme of moral judgment against the protagonist.

Conclusion. The nature in the story turns out to be ambivalent: it promises “a quiet, beautiful, eternal life” and at the same time threatens with the mute desperation of nothingness. This ambivalence can be found in other works by Chekhov, too. Besides this, the cemetery landscape introduces into the story the theme of temporality of everything on earth. The landscape of the cemetery at night also has the combination of sex and death present in it. This Freudist combination can be found in the writer’s other works, too.
Diagnosis of Leprosy: Current Updates and Future Directions
Authors: Bathula Savitha , Khurana Ananta , Singh Itu
Published: February 2023

Leprosy is a chronic infectious granulomatous disorder caused by Mycobacterium leprae, chiefly affecting skin and peripheral nerves. It is the only known bacteria to infect nerves. Clinical diagnosis of leprosy is made when any of the three cardinal signs defined by the World Health Organisation is present. However, leprosy has varied presentations necessitating laboratory diagnostic methods for diagnosis as well as treatment initiation and monitoring. Slit-skin smears and histopathology form the basic diagnostics of maximum utility, while neurological studies, cytology and imaging have significant specific roles. Novel molecular and serological tests are of value in the diagnosis of early, indeterminate, and paucibacillary leprosy, and for screening of asymptomatic contacts. Molecular methods have in addition found an important place in diagnosis of drug resistance in leprosy.
Temperature Dependence of the Relative Rates of Chlorination and Hydrolysis of N2O5 in NaCl-Water Solutions.
Authors: Kregel Steven J. , Derrah Thomas F. , Moon SeokJin , Limmer David T. , Nathanson Gilbert M. , Bertram Timothy H.
Published: February 2023

We have measured the temperature dependence of the ClNO2 product yield in competition with hydrolysis following N2O5 uptake to aqueous NaCl solutions. For NaCl-D2O solutions spanning 0.0054 M to 0.21 M, the ClNO2 product yield decreases on average by only 43 % from 5 to 25 C. Less reproducible measurements at 0.54 M and 2.4 M NaCl also fall within this range. The ratio of the rate constants for chlorination and hydrolysis of N2O5 in D2O is determined on average to be 1150±90 at 25 C up to 0.21 M NaCl, favoring chlorination. This ratio is observed to decrease significantly at the two highest concentrations. An Arrhenius analysis reveals that the activation energy for hydrolysis is just 3.0±1.5 kJ/mol larger than for chlorination up to 0.21 M, indicating that Cl- and D2O attack on N2O5 have similar energetic barriers despite the differences in charge and complexity of these reactants. In combination with the measured pre-exponential ratio favoring chlorination of {300\ }_{-200}^{+400}, we conclude that the strong preference of N2O5 to undergo chlorination over hydrolysis is driven by dynamic and entropic, rather than enthalpic, factors. Molecular dynamics simulations elucidate the distinct solvation between strongly hydrated Cl- and the hydrophobically solvated N2O5. Combining this molecular picture with the Arrhenius analysis implicates the role of water in mediating interactions between such distinctly solvated species and suggests a role for diffusion limitations on the chlorination reaction.
Copper-Phosphido Catalysis: Enantioselective Coupling of Phosphines and Cyclopropenes
Authors: Daniel Brian S. , Hou Xintong , Corio Stephanie A. , Weissman Lindsey M. , Dong Vy M. , Hirschi Jennifer S. , Nie Shaozhen
Published: February 2023

We describe a copper-catalyst that promotes the addition of phosphines to cyclopropenes at ambient temperature. A range of cyclopropylphosphines bearing different steric and electronic properties can now be accessed in high yields and enantioselectivities. A combined experimental and theoretical mechanistic study supports insertion of a Cu(I)-phosphido intermediate into the strained olefin. Density functional theory calculations reveal migratory insertion as the stereodetermining step of the pathway, with final product formation occurring via a syn-protodemetalation. Enrichment of phosphorus stereocenters is demonstrated via a DyKAT process.
Evolution of Multicomponent [Pd2ABCD] Cages
Authors: Wu Kai , Benchimol Elie , Baksi Ananya , Clever Guido
Published: February 2023

Synthetic supramolecules, inspired by biological hosts, catalysts and machines, promise to find application in sustainable synthesis, separation, energy conversion and medicine. However, the implementation of multiple functionalities within distinct self- assembled structures still poses considerable challenges. In particular metal-mediated assemblies are difficult to form from multiple chemically different building blocks without falling into narcissistic self-sorting or a statistical mess. Here we report a systematic series of integratively self-assembled heteroleptic cages in which two square-planar PdII cations are bridged by four chemically different bis-pyridyl ligands A, B, C and D via a collection of synergistic effects to form a single isomer of lantern-shaped cage [Pd2ABCD] as exclusive product. This ultimate self-sorting goal, forming just one out of 55 possible structures, is reached under full thermodynamic control and can be realized progressively (by combining heteroleptic progenitors such as [Pd2A2C2] with [Pd2B2D2]), directly from ligands and PdII cations, or most impressively by mixing all four corresponding homoleptic cages. Structural and mechanistic details were comprehensively examined by NMR and mass spectrometry and nine single crystal X-ray structures. The rational design of complex multicomponent assemblies, formed in high yield under thermodynamic control, allows to incorporate different chemical moieties in a modular approach and advance the application level of functional nanosystems.
Interfacial Electromigration for Accelerated Reactions and Small-Volume Analysis
Authors: Edwards Madison , Freitas Dallas , Hirtzel Erin , White Nicholas , Wang Hongying , Sun Yuxiang , Yan Xin
Published: February 2023

Microdroplets have recently emerged as a unique form of a chemical reactor that has gained significant attention due to the interfacial chemistry that produces dramatic reaction acceleration. In this work, we have developed a strategy that allows a thin film to be delivered directly to the interface by electromigration in a theta capillary. Additional acceleration was observed due to reactants being transferred to the interface in electro-oxidative C-H/N-H coupling of phenothiazine with N, N’-dimethylaniline, and short-lived intermediates were captured in the radical radical coupling of DMA. Importantly, we applied the combination of electromigration and interfacial microreactor for in-situ extraction of lipids from small-volume plasma samples and accelerated electro-epoxidation of unsaturated lipids to determine the double bond positional isomers in the small-volume serum. The unique feature of electromigration of thin film to the interface and accelerated interfacial reactions holds great potential in small-volume sample analysis for disease diagnosis and prevention.
Venciendo los desafíos para la inclusión de mujeres en STEM
Authors: Dávila Guillermo , Guzmán Indira , Quintanilla Claudia , Maciel Cristiano
Published: February 2023

Los cambios disruptivos en organizaciones y sociedades originados en áreas como la tecnología, economía y medioambiente desafían la flexibilidad de empresas e instituciones. En este contexto, se ha incrementado la demanda por profesionales e investigadores especialmente en áreas como STEM. La falta de investigadores y profesionales en STEM es un problema, en particular en los países latinoamericanos. En ese sentido, la inclusión de mujeres en STEM ha sido catalogada como un desafío clave y, en consecuencia, se ha convertido en un tópico que viene recibiendo creciente atención por parte de académicos y líderes políticos. Existen diversos proyectos en curso (como el Proyecto ELLAS, financiado por el International Development Research Centre, Canadá) que vienen trabajando en distintas iniciativas para cerrar las brechas de género existentes en STEM. En el presente panel, discutiremos las principales barreras existentes en Latinoamérica para la inclusión de mujeres en este campo. Además, abordaremos iniciativas y buenas prácticas que han servido para mitigar algunas de esas barreras; y, finalmente, analizaremos la aplicabilidad de estas medidas exitosas en contextos como el peruano.
SER0 Tawa Pukllay: sistema educativo remoto online/offline
Authors: Guzmán Jiménez Rosario , Escotto Córdova Eduardo Alejandro , Saldívar Álvaro , Prem Dhavit
Published: February 2023

La recuperación del conocimiento matemático inca a través del método Tawa Pukllay es un recurso de la alternancia semiótica que facilita el aprendizaje de la aritmética básica. Paralelamente, la educación rural presenta muchos retos que se han puesto de manifiesto en la pandemia del COVID-19. El sistema online/offline fue una respuesta concreta para que, a través de un juego serio con una interfaz bilingüe (quechua y español) en tablets, sea posible la continuidad de estudio y aprendizaje de la aritmética básica en niños de zonas rurales de una comunidad andina del Perú. SER0 Tawa Pukllay estimuló la iniciación de los niños en el manejo de dispositivos electrónicos manteniendo su identidad, reforzando la lingüística quechua, la cosmovisión andina, así como su autonomía. Esto permitió el autoaprendizaje y motivación para superar los retos planteados en su proceso de aprendizaje de lectura de números y operaciones aritméticas, soportado en un enfoque pedagógico lúdico y el desarrollo de su pensamiento matemático.
Algoritmos supervisados de machine learning para determinar la ubicación de dispositivos wifi
Authors: More Sánchez Javier
Published: February 2023

El presente artículo tiene como objetivo elegir, bajo un determinado escenario, el mejor algoritmo supervisado de machine learning para localizar un terminal que soporte wifi. Se usa un dataset que cuenta con 2000 registros de Received Signal Strength Indicator (RSSI), obtenidos de 7 puntos de acceso (AP), los cuales se cargan en 8 algoritmos supervisados de machine learning. Luego se elige el algoritmo que realiza la predicción más precisa, incluso cuando se cuenta con un menor número de AP. La mayor precisión se logra con el algoritmo naive Bayes, tanto para el caso de 7 AP (99 % de precisión) como para cuando se cuenta con un número menor de AP. Asimismo, se observa que los algoritmos basados en redes neuronales presentan el peor rendimiento. Finalmente, se proponen trabajos futuros para continuar con la investigación sobre el tema de localización de dispositivos wifi en interiores.
Revisión de algoritmos de detección de malware ofuscado basados en machine learning
Authors: Villarroel Enriquez Erly Galia
Published: February 2023

Los desarrolladores de malware cada vez evolucionan más sus técnicas para lograr atacar efectivamente el sistema, una de estas técnicas es la ofuscación de código que dificulta la detección de malware en los mecanismos tradicionales que utilizan los antivirus actuales. Ante ello se propone la revisión de artículos relacionados a detección de malware ofuscado con machine learning para elegir las mejores técnicas de análisis de este tipo de malware y emplear los mejores algoritmos para una futura experimentación con los mismos.
Aberrant association of chromatin with nuclear periphery induced by Rif1 leads to mitotic defect
Authors: Kanoh Yutaka , Ueno Masaru , Hayano Motoshi , Kudo Satomi , Masai Hisao
Published: February 2023

The architecture and nuclear location of chromosomes affect chromatin events. Rif1, a crucial regulator of replication timing, recognizes G-quadruplex and inhibits origin firing over the 50–100-kb segment in fission yeast,Schizosaccharomyces pombe, leading us to postulate that Rif1 may generate chromatin higher order structures inhibitory for initiation. However, the effects of Rif1 on chromatin localization in nuclei have not been known. We show here that Rif1 overexpression causes growth inhibition and eventually, cell death in fission yeast. Chromatin-binding activity of Rif1, but not recruitment of phosphatase PP1, is required for growth inhibition. Overexpression of a PP1-binding site mutant of Rif1 does not delay the S-phase, but still causes cell death, indicating that cell death is caused not by S-phase problems but by issues in other phases of the cell cycle, most likely the M-phase. Indeed, Rif1 overexpression generates cells with unequally segregated chromosomes. Rif1 overexpression relocates chromatin near nuclear periphery in a manner dependent on its chromatin-binding ability, and this correlates with growth inhibition. Thus, coordinated progression of S- and M-phases may require regulated Rif1-mediated chromatin association with the nuclear periphery.
SRSF7 and SRSF3 depend on RNA sequencing motifs and secondary structures to regulate Microprocessor
Authors: Le Minh Ngoc , Nguyen Trung Duc , Nguyen Tuan Anh
Published: February 2023

Human Microprocessor cleaves pri-miRNAs to initiate miRNA biogenesis. The accuracy and efficiency of Microprocessor cleavage ensure appropriate miRNA sequence and expression and thus its proper gene regulation. However, Microprocessor cleaves many pri-miRNAs incorrectly, so it requires assistance from many cofactors. For example, SRSF3 enhances Microprocessor cleavage by interacting with the CNNC motif in pri-miRNAs. However, whether SRSF3 can function with other motifs and/or requires the motifs in a certain secondary structure is unknown. In addition, the function of SRSF7 (a paralog of SRSF3) in miRNA biogenesis still needs to be discovered. Here, we demonstrated that SRSF7 could stimulate Microprocessor cleavage. In addition, by conducting high-throughput pri-miRNA cleavage assays for Microprocessor and SRSF7 or SRSF3, we demonstrated that SRSF7 and SRSF3 function with the CRC and CNNC motifs, adopting certain secondary structures. In addition, SRSF7 and SRSF3 affect the Microprocessor cleavage sites in human cells. Our findings demonstrate the roles of SRSF7 in miRNA biogenesis and provide a comprehensive view of the molecular mechanism of SRSF7 and SRSF3 in enhancing Microprocessor cleavage.
Endosymbionts that threaten commercially raised and wild bumble bees (Bombus spp.)
Authors: Figueroa Laura , Sadd Ben , Tripodi Amber , Strange James , Colla Sheila , Adams Laurie , Duennes Michelle , Evans Elaine , Lehmann David , Moylett Heather , Richardson Leif , Smith James , Smith Tamara , Spevak Edward , Inouye David W.
Published: February 2023

Bumble bees (Bombus spp.) are important pollinators for both wild and agriculturally managed plants. We give an overview of what is known about the diverse community of internal potentially deleterious bumble bee symbionts, including viruses, bacteria, protozoans, fungi, and nematodes, as well as methods for their detection, quantification, and control. We also provide information on assessment of risk for select bumble bee symbionts and highlight key knowledge gaps. This information is crucial for ongoing efforts to establish parasite-free programs for future commerce in bumble bees for crop pollination, and to mitigate the problems with pathogen spillover to wild populations.
Development of Brief Alcohol and Cannabis Motives Measures: Psychometric Evaluation Using Expert Feedback and Longitudinal Methods
Authors: Bartel Sara , Sherry Simon , Mahu Ioan , Stewart Sherry
Published: February 2023

Objective: Alcohol and cannabis use motives are often studied as contributors to risky substance use patterns. While various measures for capturing such motives exist, most contain 20+ items, which render their inclusion in certain research designs (e.g., daily diary) or with certain populations (e.g., polysubstance users) unfeasible. We sought to generate and validate six-item measures of cannabis and alcohol motives from existing measures, the Marijuana Motives Measure (MMM) and the Modified Drinking Motives Questionnaire-Revised (MDMQ-R). Methods: In Study 1, items were generated, feedback from 33 content-domain experts was obtained, and item revisions were made. In Study 2, the finalized brief cannabis and alcohol motives measures, along with the MMM, MDMQ-R, and substance-related measures, were administered to 176 emerging adult cannabis and alcohol users (71.6% female) at two timepoints, two months apart. Participants were recruited through a participant pool. Results: Study 1 experts indicated satisfactory ratings of face and content validity. Expert feedback was used to revise three items. Study 2 results suggest test-retest reliabilities for the single-item forms (r = .34 to .60) were similar to those obtained with full motives measures (r = .39 to .67). Validity was acceptable-to-excellent in that brief and full-length measures were significantly intercorrelated (r = .40 to .83). The brief and full-length measures had similar concurrent and predictive relationships for cannabis and alcohol quantity x frequency (coping-with-anxiety for cannabis and enhancement for alcohol) and problems (coping-with-depression), respectively. Conclusions: The brief measures represent psychometrically-sound measures of cannabis and alcohol use motives with substantially less participant burden than the MMM and MDMQ-R.
O ESTUÁRIO DO RIO POTENGI, PASSADO E PRESENTE: CARTA DE ZONEAMENTO ARQUEOLÓGICO SUBAQUÁTICO DO SÉCULO XVII
Authors: Noemi França Miranda Anne , Airon Silva Roberto
Published: February 2023

This article is the result of the final course work entitled “In the waters of the Potengi River: Underwater Archaeological Zoning Chart (17th century)” presented to the undergraduate course in History at the Federal University of Rio Grande do Norte. The Potengi River, also known in the 16th and 17th centuries as Pottiou, Rio Grande, Puttigi, Potiji, among others, was already known as a favorable space for navigation, as evidenced by cartographies, iconography and accounts of french, portuguese and dutch travelers from the century 16th and 17th. Using an interdisciplinary approach between History and Archaeology, this article aims to present the areas of underwater archaeological potential in the Potengi River estuary from the 17th century, taking into account the disturbances of the archaeological context over the years, finally presenting the archaeological zoning chart of the area, an important tool for the management of the municipal underwater archaeological heritage.
Eosinophilic pustular folliculitis in a 90-year-old patient
Authors: Cichoń Mikołaj , Wańczyk-Dręczewska Beata , Placek Waldemar , Biernat Wojciech , Potocka Wiktoria , Owczarczyk-Saczonek Agnieszka
Published: February 2023

Introduction

Eosinophilic pustular folliculitis (EPF), sometimes called Ofuji disease, is a chronic skin disorder of unknown etiology which develops predominantly in elderly man. Clinically it usually presents as itching centrifugally extending papulopustular rash.

Aim

To present a case of EPF and to raise dermatologists’ awareness of this this dermatosis when dealing with patients who are in higher risk of EPF occurrence.

Case study

A 90-year-old man presented to the dermatology clinic due to the itching rash that had been present for 3 months. Physical examination of the patient revealed red-brown papulopustules covering trunk and extremities, most severe on the frontal part of thighs. Other possible causative agents of the symptoms were excluded. Histopathological results together with clinical symptoms led us to the final diagnosis of classic EPF.

Results and discussion

EPF is challenging to diagnose. The disease is very rare, especially in Europe, and clinical and/or histological appearance may mimic other dermatological conditions. The most commonly affected areas are face, back and trunk. EPF is usually classified into three main subtypes: classic, infantile and immunosuppression-associated. There are many viable therapeutic algorithms for the treatment of EPF.

Conclusions

Eosinophilic pustular folliculitis should be considered in differential diagnosis of pruritic follicular papulopustular rash affecting elderly men. Histopathological results play a crucial role in the making of final diagnosis.
Influencia de la potencia de depósito en la morfología de películas delgadas de óxidos de molibdeno depositadas por el método de sputtering.
Authors: Mora-Leyva A. N. , Alfaro Cruz M. R. , Torres-Martínez Leticia M.
Published: February 2023

En este trabajo se presenta la influencia de la potencia en el depósito por sputtering en la morfología de películas delgadasde óxidos de molibdeno. Las películas fueron depositadas variando la potencia de depósito en 10, 20, 30, 40 y 50 W, endonde los espesores de las películas fueron de 46, 72, 218, 222 y 226 nm respectivamente. Las películas de óxido demolibdeno tienen una contribución de diferentes fases de los óxidos de molibdeno como MoO2 (tetragonal yortorrómbica), MoO3 (ortorrómbica) y el Mo30 (cúbica). La variación en la potencia de depósito permite el crecimientopreferencial de ciertos planos cristalinos de los óxidos de molibdeno. Las películas a bajas potencias presentaron unasuperficie homogénea con la aparición de algunos precipitados. Mientras que las películas depositadas con una potenciamayor presentaron una morfología en forma de barras orientadas en diferentes direcciones. El índice de refracción de laspelículas con una morfología de barras es mayor que el índice de refracción de las películas depositadas a una menorpotencia. Lo que confirma que el paso de la luz a través de la superficie es mucho mas lento para las películas depositadasa potencias mayores de 30 W que para las películas depositadas a 10 y 20 W.
Pertanggunggugatan PT. ASDP Terhadap Penumpang Yang Tidak Tercatat Identitasnya Saat Terjadi Kecelakan Kapal Ferry
Authors: Hidayat Anwar , Sudiarto Sudiarto
Published: February 2023

Pada angkutan penyeberangan menggunakan ferry, seringkali identitas penumpang tidak tercatat di tiket. Beberapa penumpang bahkan tidak memiliki tiket. Penelitian ini bertujuan untuk mengetahui akuntabilitas PT. ASDP pada penumpang yang tidak tercatat identitasnya pada kecelakaan penyeberangan. Manfaat kajian diharapkan dapat menjawab keraguan atas isu terkait pencatatan calon penumpang angkutan laut. Penelitian dilakukan dengan menggunakan metode normatif. Hasil penelitian mengungkapkan adanya ketidaksesuaian antara peraturan dengan kejadian sebenarnya dalam pencatatan penumpang. Setiap penumpang harus memiliki tiket sesuai identitasnya untuk membuktikan perjanjian pengangkutan dan jaminan asuransi Jasa Raharja.
Analisis Hukum Terhadap Penyelewengan Dana Nasabah (FRAUD) Berdasarkan Prinsip Kepercayaan
Authors: Savitri Nurchalizah Yasmine , Setiawan Yudhi
Published: February 2023

Tujuan dari penelitian ini adalah untuk mengetahui hubungan antara perbuatan penyelewengan dana nasabah (fraud) dengan prinsip kepercayaan dan untuk mengetahui perlindungan hukum bagi nasabah atas tindakan fraud. Sedangkan manfaat dari penelitian ini diharapkan dapat memberikan masukan pada semua pihak yang membutuhkan pengetahuan terkait dengan permasalahan yang diteliti. Metode yang digunakan adalah penelitian normatif dengan menggunakan bahan hukum primer, sekunder, dan tersier. Hasil dari penelitian ini menyebutkan bahwa prinsip kepercayaan itu sangat penting bagi keberlangsungan suatu lembaga perbankan, yang mana jika tidak ada kepercayaan dari masyarakat, bank tidak dapat melaksanakan kegiatan usahanya untuk itu bank harus senantiasa menjaga kepercayaan nasabah dengan menjaga kesehatan banknya serta memberikan perlindungan baik secara preventif maupun represif kepada nasabah agar mereka merasa aman dan nyaman bertransaksi di bank yang bersangkutan.
Perlindungan Hukum Bagi Konsumen Terhadap Perdagangan Barang Rekondisi Elektronik Di Kota Mataram
Authors: Pendi Pendi , Sutrisno Budi
Published: February 2023

Tujuan penelitian adalah untuk mengetahui perlindungan hukum bagi konsumen terhadap perdagangan barang rekondisi elektronik di Kota Mataram dan untuk mengetahui tanggung Jawab pelakuusaha terhadap perdagangan barang rekondisi elektronik di Kota Mataram. Jenis penelitian adalah normatif-empiris dengan pedekatan perundang-undangan, konseptual, dan Sosiologis. Berdasarkan hasil penelitian. Perlindungan hukum bagi konsumen terhadap perdagangan barang rekondisi elektronik di Kota Mataram, terlihat bahwa masalah kenyamanan, keamanan, dan keselamatan konsumen merupakan hal yang paling pokok dan utama dalam perlindungan konsumen. Tanggung Jawab pelaku usaha terhadap perdagangan barang rekondisi elektronik di Kota Mataram berdasarkan Undang-Undang Nomor 8 tahun 1999 tentang Perlindungan Konsumen yaitu konsumen memperoleh kompensasi ganti rugi atas kerugian yang dialaminya karena barang yang diterima tidak sesuai sebagaimana mestinya dengan memberikan ganti rugi berupa pengembalian uang atau penggantian barang yang sejenis/sesuai harga.
ANALISIS PENERAPAN KONSEP ERGONOMI UNTUK MENDESAIN MESIN POTONG KULIT KERANG MUTIARA
Authors: Joniarta I Wayan , Wijana Made , Chatur Adi W.A. I G.A.K. , Bawa Susana I Gede , Suartika I Made
Published: February 2023

The application of the concept of ergonomics is carried out on seashell craft work facilities because the work facilities used are not in accordance with the principles and norms of ergonomics feasibility. The research objective is the redesign of cutting machines and work chairs based on various kinds of information related to human factors which include designing tools and work facilities that are more effective, safe, comfortable, healthy, and efficient (ENASE). Some of the ergonomic parameters that are used as references include aspects of anthropometry, human physical performance, effectiveness-efficiency, work productivity, and the subjectivity of complaints of body pain as a result of inappropriate positions and workloads. In this study, 1 unit of circular model of shell cutting machine was designed and 1 unit of chair / seat. With anthropometric measurements of employees and through ergonomic calculations using the 5th percentile, the dimensions of the work table (cutting table) were obtained, the size of the table height was 87, 9 cm long table 110 cm and table width 64.3 cm. Then the dimensions of the chair are also obtained as follows: seat base height 32.7 cm Chair base length 70.6 cm Chair base width 32.1 cm chair back height 56.8 cm cm, seat back width 44.5 cm After applying the principles of ergonomics, based on the results of the Nordic Body Map questionnaire, it was found that the application of ergonomic principles to work tools for clam shell workers resulted in a 128% decrease in musculoskeletal complaints. In addition to this, it also resulted in a decrease in fatigue levels of 103%. . This shows that the application of ergonomic principles has a positive impact on employees