bluuebunny/crossref_metadata_2025 huggingface dataset:
Developing a Digital Twin and Digital Thread Framework for an ‘Industry 4.0’ Shipyard
Authors: Pang Toh Yen , Pelaez Restrepo Juan D. , Cheng Ben , Yasin Alim , Lim Hailey , Miletic Miro
Published: December 2020

This paper provides an overview of the current state-of-the-art digital twin and digital thread technology in industrial operations. Both are transformational technologies that have the advantage of improving the efficiency of current design and manufacturing. Digital twin is an important element of the Industry 4.0 digitalization process; however, the huge amount of data that are generated and collected by digital twin offer challenges in handling, processing and storage. The paper aims to report on the development of a new framework that combines the digital twin and digital thread for better data management in order to drive innovation, improve the production process and performance, and to ensure continuity and traceability of information. The digital twin/thread framework incorporated behavior simulation and physical control components, in which these two components rely on the connectivity between the twin and thread for information flow and exchange to drive innovation. The twin/thread framework encompasses specifications that include organizational architecture layout, security, user access, cloud computing set-up, and hardware and software requirements. It is envisaged that the framework will be applicable to enhancing optimization of operational processes and traceability of information in the physical world, especially in Industry Shipyard 4.0.
Exploration of Financial Management Operation of Political and Non-Political Student Organization:a Basis for Propose Policy Development
Authors: DIAZ ROWELL , De Leon Clarizza , Vitug Edgelly , Linsangan Lester
Published: December 2020

: A strong financialtransaction is an important factor in organizational triumph and sustainability, and it is elucidated in the revised student handbook of the University that can be found on page 96 rules 1 to 5. This study assessed the registered students organizations' profile in terms of its type, registration, years of establishment, functions, and designations of student leaders and advisers. The financial practices or internal control system manages their organizational finances and the problems encountered by the student organizations and eventually proposed a manual of operation for students and youth organization's internal control system. This research used the descriptive design with the aid of questionnaire; data gathering through quota sampling from 57 student leaders and advisers of different student organizations of NEUST. Findings showed that most organizations had their constitution and by-laws but kept only as files and renewal requirements. Some provisions were not known to the officers, mostly were registered more than five years in operation; however, in terms of functions of officers and advisers, the results showed that some functions were not done by the officers who supposed to do it like the auditors who serve as treasurers also, the PRO as the record keeper and the presidents who handled finances and collections and as well as disbursements of funds. Generally, the organizations' financial activities were deemed to be "good", especially budgeting and cash receipt, due to the implementation of "no collection and no tuition fee policy". The researchers concluded that the absence of the proper internal control systems and manual of operation and lack of proper transfer of financial records from the previous sets of officers were the serious problems that should be addressed. Moreover, the student organizations' internal control system could still be improved if there is proper training and supervision in accounting operation.
Cryopreservation for Tree Species with Recalcitrant Seeds: the Avocado Case
Authors: O'Brien Chris , Hiti-Bandaralage Jayeni , Folgado Raquel , Hayward Alice , Lahmeyer Sean , Folsom Jim , Mitter Neena
Published: December 2020

Recent developments in the cryopreservation space has increased the trend in germplasm collections established through cryopreserved in vitro material. Cryopreservation of recalcitrant seeds through embryos and embryonic axes, is not uncommon. Tropical and sub-tropical plants are not acclimated to the cold season, therefore have no in-built natural resilience to the cold. Also, larger seeds from trees, such as avocado (Persea americana Mill.), mango (Mangifera indica) and durian (Durio zibethinus L.) are sensitive to desiccation, chilling and freezing stress, making them unsuitable for seed banking or cryopreservation. Alternatively, as seeds do not carry the same genetic make-up as the mother plant, especially in the context of woody rainforest species of which the cross-pollination is dominant; seed conservation does not serve the purpose of germplasm preservation. Other plant material and methods are needed for these plants to be successfully stored in liquid nitrogen (LN). One such method commonly used is shoot-tip cryopreservation which ensures the clonal fidelity of germplasm. There are many problems when using shoot tips of tropical recalcitrant-seeded species. These include: 1) the toxic effects of cryoprotective agents towards structural integrity; 2) optimum developmental stage for success and 3) oxidative stress associated with excision injury leading to necrosis triggering cell death and hindering regeneration for the shoot tips in culture. A pre-requisite for any cryopreservation system is the availability of an established tissue culture regeneration platform. This review will outline conservation strategies for avocado with special emphasis on attempts and improvements made in the cryopreservation space for storing this horticulturally important crop ‘avocado’ at ultra-low temperatures.
The Optimizing Background Infusion Mode Decreases Intravenous Patient-Controlled Analgesic Volume Compared to Fixed-Rate Background Infusion in Patients Undergoing Laparoscopic Cholecystectomy: A Prospective, Randomized, Controlled, Double-Blind Study
Authors: Jung Ki Tae , So Keum Young , Kim Seung Un , Kim Sang Hun
Published: December 2020

Background and objectives: Traditional intravenous, patient-controlled analgesia (PCA) uses a fixed-rate continuous background infusion mode. However, some patients suffer from inadequate analgesia or opioid-related adverse effects due to the biphasic pattern of postoperative pain. Therefore, we investigated the postoperative analgesic efficacy of PCA using an optimizing background infusion mode (OBIM), where the background injection rate varies depending on the patient's bolus demand. Materials and Methods: We prospectively enrolled 204 patients who underwent laparoscopic cholecystectomy in a randomized, controlled, double-blind study. Patients were allocated into either the optimizing (group OBIM) or the traditional background infusion group (group TBIM). The numeric rating scale (NRS) score for pain was evaluated at admission to and discharge from the recovery room, as well as at the 6th, 24th, and 48th postoperative hours. Data of bolus demand count, total infused volume, and background infusion rate was downloaded from the PCA device at 30-min intervals until the 48th postoperative hour. Results: The NRS score was not significantly different between groups throughout the postoperative period (P = 0.621), decreasing with time in both groups (P < 0.001). The bolus demand count was not significantly different between groups throughout (P = 0.756). The mean cumulative infused PCA volume was lower in group OBIM [84.0 (95% confidence interval: 78.9−89.1) mL) than in group TBIM [102 (97.8−106.0) mL] (P < 0.001). The background infusion rate was significantly different between groups throughout (P < 0.001); it was higher in group OBIM than in group TBIM before the 12th postoperative hour, and lower from the 18th to the 48th postoperative hours. Conclusions: The OBIM combined with bolus dosing is useful in that it reduces the cumulative PCA volume compared to the TBIM combined with bolus dosing, while yielding comparable postoperative analgesia and bolus demand in patients undergoing laparoscopic cholecystectomy.
Exfoliation Energy as a Descriptor of MXenes Synthesizability and Surface Chemical Activity
Authors: Dolz Daniel , Morales-García Ángel , Viñes Francesc , Illas Francesc
Published: December 2020

MXenes are two-dimensional nanomaterials isolated from MAX phases by the selective extraction of the A component —a p-block element. The MAX phase exfoliation energy, Eexf, is regarded as a chemical descriptor of the MXene synthesizability. Here we show, by density functional theory estimations of the Eexf values for 486 different MAX phases, that Eexf decreases i) when MAX is a nitride, ii) when going along a d series of the metal M component, iii) when going down a group of the p-block A element, as well as iv) when having thicker MXene phases. Furthermore, Eexf is found to bias, even to govern, the surface chemical activity, as evaluated here on the CO2 adsorption strength, so that more unstable MXenes, displaying larger Eexf values, display a stronger attachment of species upon.
Intelligent Cyber-Attack Detection and Classification for Network-based Intrusion Detection Systems
Authors: Oliveira Nuno , Praça Isabel , Maia Eva , Sousa Orlando
Published: December 2020

With the latest advances in information and communication technologies, greater amounts of sensitive user and corporate information are constantly shared across the network making it susceptible to an attack that can compromise data confidentiality, integrity and availability. Intrusion Detection Systems (IDS) are important security mechanisms that can perform a timely detection of malicious events through the inspection of network traffic or host-based logs. Throughout the years, many machine learning techniques have proven to be successful at conducting anomaly detection but only a few considered the sequential nature of data. This work proposes a sequential approach and evaluates the performance of a Random Forest (RF), a Multi-Layer Perceptron (MLP) and a Long-Short Term Memory (LSTM) on the CIDDS-001 dataset. The resulting performance measures of this particular approach are compared with the ones obtained from a more traditional one, that only considers individual flow information, in order to determine which methodology best suits the concerned scenario. The experimental outcomes lead to believe that anomaly detection can be better addressed from a sequential perspective and that the LSTM is a very reliable model for acquiring sequential patterns in network traffic data, achieving an accuracy of 99.94% and a f1-score of 91.66%.
Perceptions of Students Toward Digital Transformation in University Teaching
Authors: Díaz-Noguera María Dolores , Hervás-Gómez Carlos , Guijarro-Cordobés Olga , Domínguez-González María de los Ángeles
Published: December 2020

The management of a cultural change in higher education is becoming necessary and unavoidable: changes in teaching, changes in research and changes in governance. Digital transformation is an essential part of many countries’ modernisation agendas. The aim of this non-experimental, descriptive, survey-based study was to explore the perceptions of university students toward the digital transformation that took place in university teaching as a consequence of COVID-19. The specific objectives proposed were to: a) analyse the perceptions of students toward digital transformation in university teaching; b) determine the valuation of students about the digital transformation that occurred in university teaching as a result of COVID-19; and c) explore the resources (hardware-software), professional collaboration, digital pedagogy and student empowerment (motivation) with respect to digital education and the recent changes in university teaching due to the pandemic. The results show that a large number of items are positively correlated. In conclusion, further research should delve into motivation, collaboration, reflective experience sharing, self-learning and initiatives that promote the development of competences in future teachers.
The Research on the Relation between PSD of Park Green Space and Attention Restoration in Dense Urban Areas
Authors: Zhu Zhixian , Wang Weijue , Chen Qibing
Published: December 2020

Research shows that stress, a common problem in dense cities, can be relieved in the natural environment. As great significance has been attached to the urban environment and public health in the society, this paper aims to study the relation and interaction between the perceived sensory dimension of urban park green space, attention restoration and state empathy. Therefore, we conducted an on-site questionnaire survey in four typical parks in Chengdu in terms of age, sex, daily stress, frequency of access in parks and other basic information of the respondents. The main part consists of perceived dimension, state empathy and attention restoration. The software SPSS24.0 is applied to the test of the validity and reliability of the PSD Scale, and then the important correlation between the perceived sensory dimensions in the parks and visitors' attention restoration is analyzed through multiple linear regression. Finally, the moderation effect of state empathy is tested by PROCESS. The findings show that (1) only seven dimensions in the PSD Scale are effective; (2) Serene and Refuge in the perceived sensory dimensions have significant effect on the restorative components of attention. (3) Except the dimensions of Rich in Species and Refuge, empathy enhanced the moderation effect in the interaction between the other five dimensions the Perceived Restorative Scale(PRS), especially in the interaction between the dimension Social and PRS. However, this study needs to be further explored to provide scientific basis and design strategy guidance for the research on the restoration potential of urban park green space in high-density urban areas.
The First 40 Million Years of Jurassic Planktonic Foraminifera
Authors: Gradstein Felix , Waskowska Anna , Glinskikh Larisa
Published: December 2020

We provide a biochronology of Jurassic planktonic foramininfera, using first order linkage to ammonite and nannofossil stratigraphy and geochronology. This enigmatic and understudied group of microfossils occurred from middle Toarcian through Tithonian time, from ~180 to ~143 Ma; its origin is unknown. There are three genera: Globuligerina, Conoglobigerina and Petaloglobigerina. The genus Globuligerina, with a smooth to pustulose test surface texture appeared in Toarcian (late Early Jurassic) and Conoglobigerina, with a rough reticulate test surface texture in Oxfordian (early Late Jurassic) time. The genus Petaloglobigerina, with a petaloid last whorl and one or more twisted and claviform chambers evolved in early Kimmeridgian time from Globuligerina balakhmatovae. We recognize stratigraphic events from eleven species across four evolutionary lineages, calibrated to Geologic Time Scale 2020. A dramatic faunal change over, which is not well documented led to the survival of only one taxon, most likely Gobuligerina oxfordiana in the Tithonian. During the Berriasian several new taxa appeared.
Hydrocephalus Revisited: New Insights Into Dynamics of Neurofluids on Macro- and Microscales
Authors: Ludwig Hans , Bock Christoph , Gärtner Jutta , Schiller Stina , Frahm Jens , Dreha-Kulaczewski Steffi
Published: December 2020

New experimental and clinical findings question the historic view of hydrocephalus and its 100-year-old classification. In particular, real-time MRI evaluation of CSF flow and detailed insights into brain water regulation on the molecular scale indicate the existence of at least three main mechanisms that determine the dynamics of neurofluids. (i) Inspiration is a major driving force (ii) Adequate filling of brain ventricles by balanced cerebrospinal fluid upsurge is sensed by cilia (iii) The perivascular glial network connects the ependymal surface to the pericapillary Virchow-Robin spaces. Hitherto, these aspects have not been considered a common physiologic framework improving knowledge and therapy for severe disorders of normal-pressure and post-haemorrhagic hydrocephalus, spontaneous intracranial hypotension and spaceflight disease.
How Big is My Carbon Footprint? Understanding Young People's Engagement with Climate Change Education
Authors: Ross Helen , Rudd Jennifer A. , Skains R. Lyle , Horry Ruth
Published: December 2020

This paper presents a new engagement model for climate change education (CCE) as a result of analysing interactive digital narratives (IDNs) created during the You and CO2 Climate Change Education Programme. Young people aged 13-15 from two schools in Wales participated in three workshops, which culminated in students producing IDNs about climate change using Twine storytelling software. An inductive, grounded-theory approach informed by Bourdieusien principles of habitus and value was used to explore students’ responses to the Programme. Stage 1 coding identified ‘Core Themes’ and located student responses along tri-axial continua showing engagement, agency, and power. Stage 2 coding combined ‘Core Themes’ to build upon Cantell’s 2019 Bicycle Model of Climate Change Education to create a new ‘Holistic Engagement Model for Climate Change Education and Action’ (HEMCCEA), where learners’ journeys towards full engagement with and understanding of CCE and action could be traced. Barriers to students’ engagement with and understanding of CCE were identified through Bourdieusien analysis of responses. Results show that engagement was related to children’s views on their capacity to effect change on individual, local and governmental level. The HEMCCEA provides a model for adjusting CCE curricula to accommodate young people’s varying cultures and views.
Rapid Prototyping of Virtual Reality Cognitive Exercises in a Tele–Rehabilitation Context
Authors: Perri Damiano , Fortunelli Martina , Simonetti Marco , Magni Riccardo , Carloni Jessica , Gervasi Osvaldo
Published: December 2020

In recent years, the need to contain healthcare costs due to the growing public debt of many countries, combined with the need to reduce costly travel by patients unable to move autonomously, have captured the attention of public administrators towards tele-rehabilitation. This trend has been consolidated overwhelmingly following the Covid-19 pandemic, which has made it precarious, difficult and even dangerous for patients to access hospital facilities. We present a platform devoted to the rapid prototyping of Virtual Reality based, cognitive tele-rehabilitation exercises. Patients who experienced injury or pathology need to practice a continuous training in order to recover functional abilities, and the therapist need to monitor the outcomes of such practices. The Virtual Reality exercises are designed on Unity 3D to empower the therapist to set up personalised exercises in a easy way, enabling the patient to receive personalized stimuli, which are crucial for a positive outcome of the practice. Furthermore, the reaction speed of the system is of fundamental importance, as the temporal evolution of the scene must proceed parallel to the patient’s movements, to ensure an effective and efficient therapeutic response. So, we optimized the Virtual Reality application in order to make the loading phase and the startup phase as fast as possible and we have tested the results obtained with many devices: in particular computers and smartphones with different operating systems and hardware. The implemented platform integrates in Nu!Reha system®, a tele-rehabilitation set of services that helps patients to recover cognitive and functional capabilities.
The Effect of Air Quality and Weather on the Chinese Stock: Evidence from Shenzhen Stock Exchange
Authors: Jiang Zhuhua , Gupta Rangan , Subramaniam Sowmya , Yoon Seong-Min
Published: December 2020

We investigate the impact of air quality and weather on the equity returns of the Shenzhen Exchange. To capture the air quality and weather effects, we use dummy variables created by employing a moving average and moving standard deviation. The important results are as follows. First, in the whole sample period (2005–2019), we find that high air pollution and extremely high temperature have significant and negative influence on the equity returns. In the sub-period I (2005–2012), the 11-day model and 31-day model show that high air pollution have significant and negative impacts on the Shenzhen stock returns. Second, the results of the quantile regression show that high air pollution have significant and negative effects during bullish market phase, and extremely high temperature have significant and negative effects during bearish market phase. This implies that the air quality and weather effects are asymmetric. Third, the weather effect of the abnormal temperature on the stock returns is greater in severe bearish market. Whereas the effect of the air pollution on the stock returns is greater in the bullish market. Fourth, the least squares method underestimates the air quality and weather effects compared to the quantile regression method, suggesting that the quantile regression method is more suitable in analyzing these effects in a very volatile emerging market such as the Shenzhen stock market.
Implementing Nature Based Solutions in Rural Landscapes; Barriers Experienced in the PHUSICOS Project
Authors: Solheim Anders , Capobianco Vittoria , Oen Amy , Kalsnes Bjørn , Wullf-Knutsen Turid , Olsen Mari , Del Seppia Nicola , Arauzo Idoia , Garcia Balaguer Eva , Strout James Michael
Published: December 2020

Nature Based Solutions (NBS) are becoming increasingly important in both the EU and individual countries' political agendas, as a sustainable means to reduce the risk posed by hydrometeorological hazards. However, as the use of NBS is increasing, a number of barriers regarding their practical implementation also becomes apparent. A number of review studies have summarized and classified barriers, mainly in urban settings. PHUSICOS is a H2020 Innovation Action to demonstrate the use of NBS in rural and mountain landscapes. Large scale demonstrator case sites with several sub-projects are established in Italy, Norway and in the French and Spanish Pyrenees. The present paper describes the project's NBS measures, and their experienced barriers, some of which have resulted in full cancellation of the planned interventions. Many of the barriers experienced in rural settings have the same root causes as the ones described from urban areas, and the main barrier-creating mechanisms are institutional factors, resistance among stakeholders and technical and economic issues. The key element, however, is lack of knowledge about the ability of NBS to deliver a series of co-benefits in addition to their risk-reducing effects, and that long-term thinking is required to see the effect of many of these co-benefits.
Therapy optimization for chronic cervicitis associated with opportunistic pathogens
Authors:   Omsk State Medical University, Omsk, Russian Federation, Polyanskaya I.B. , Savelyeva I.V. ,   Omsk State Medical University, Omsk, Russian Federation, Kochkina O.N. ,   Clinical Maternity Hospital №6, Omsk, Russian Federation, Pavilova I.N. ,   Clinical Maternity Hospital №6, Omsk, Russian Federation, Gimp M.V. ,   Clinical Maternity Hospital №6, Omsk, Russian Federation, Potyakina C.C. ,   Clinical Maternity Hospital №6, Omsk, Russian Federation, Grigorian R.A. ,   Clinical Maternity Hospital №6, Omsk, Russian Federation
Published: December 2020

Objective. To assess the effectiveness of chronic cervicitis treatment with the combined antimicrobial medication Vagiferon, vaginal suppositories. Patients and methods. This paper presents the study results of the topical therapy effectiveness in 76 patients of reproductive age (28 ± 3 years) with chronic cervicitis. The medication Vagiferon was administered vaginally, one suppository once daily for 10 days. The criteria for the treatment effectiveness were the disappearance of clinical disease manifestations and normalization of laboratory parameters. Results. The clinical and laboratory therapy effectiveness was 86.8%. Eradication of Gardnerella vaginalis and E. Coli was observed, the number of white blood cells in the smear was on average 13 in the field of view. Ineffectiveness or insufficient effectiveness of the therapy was recorded in 13.2%. No serious side effects were registered in the assessment of the medication safety and tolerability. Conclusion. High effectiveness of the combined antimicrobial medication Vagiferon in the treatment of chronic cervicitis was shown, which allows us to prevent recurrence of the inflammatory process and reduce the risk of epithelial dysplasia in patients with chronic cervicitis. Keywords: colposcopy, cervical pathology, reproductive age, cervicitis, therapy, Vagiferon
Impact of focused ultrasound energy during magnetic resonance imaging-guided ablation of uterine fibroids on endometrial receptivity in patients of reproductive age
Authors:   Ural Research Institute of Maternity and Infant Care, Yekaterinburg, Russian Federation, Melkozerova O.A. , Shchedrina I.D. ,   Ural Research Institute of Maternity and Infant Care, Yekaterinburg, Russian Federation;, Grishkina А.А. ,   Ural Research Institute of Maternity and Infant Care, Yekaterinburg, Russian Federation;, Chistyakova G.N. ,   Ural Research Institute of Maternity and Infant Care, Yekaterinburg, Russian Federation;, Bragina E.E. ,   M.V.Lomonosov Moscow State University, Moscow, Russian Federation
Published: December 2020

Objective. To study the impact of the energy of focused ultrasonic waves during focused ultrasound ablation of uterine fibroids guided by magnetic resonance imaging (MRI-FUS) on the parameters of endometrial receptivity. Patients and methods. A prospective cohort study of 67 reproductive-age women suffering from uterine fibroids. The treatment group comprised 32 patients, who underwent treatment for a uterine fibroid by MRI-FUS ablation. The comparison group consisted of 35 women, who underwent laparoscopic myomectomy. The control group included 28 fertile healthy women. The endometrial tissue obtained with the use of pipelle biopsy pipelle biopsia on the 20–22th day of the cycle was examined by the method of light and scanning electron microscopy before and three months after treatment. Results. The ultrastructural parameters of endometrial receptivity in patients with uterine fibroids were characterised by a phase delay in the pinopode development rates (88.57 vs. 21.42% in control; р < 0.05), a high incidence of tight junctions (34.29 vs. 7.14% in control; р = 0.021) and atypical cells of the microenvironment (54.29 vs. 7.14%; р = 0.005). No significant changes in the pinopode development rates were noted after myomectomy, the incidence of their asynchronous development significantly decreased (54,29 vs. 20.00%; р = 0.011). No significant changes in the pinopode development rates were noted after MRI-FUS ablation of uterine fibroids either, conversely, a significant increase of their asynchronous development was established (50.00 vs. 14.28%; р = 0.021) as well as a higher number of heteromorphic secretory cells (53.33 vs. 5.88%; р = 0.002) in the endometrium. Conclusion. The use of non-invasive methods of treatment of uterine fibroids in patients who are planning a pregnancy should be well grounded and take into consideration the character and causes of previous reproductive failures. Key words: magnetic resonance imaging, uterine fibroids, myomectomy, pinopodes, focussed ultrasound ablation, endometrium
Assessment of the effectiveness of physiotherapeutic methods for management of early menopause disorders
Authors:   National Medical Research Centre for Rehabilitation and Balneology, Moscow, Russian Federation, Kotenko N.V. , Barashkov G.N. ,   National Medical Research Centre for Rehabilitation and Balneology, Moscow, Russian Federation, Salamadina G.E. ,   National Medical Research Centre for Rehabilitation and Balneology, Moscow, Russian Federation, Borisevich О.О. ,   National Medical Research Centre for Rehabilitation and Balneology, Moscow, Russian Federation
Published: December 2020

Objective. Assessment of the effectiveness of pelotherapy in combination with phytoaromatic baths in women during menopause transition. Patients and methods. We examined 26 women aged 52 ± 2.4 years. All women with vegetative-vascular manifestations of the climacteric syndrome were randomly assigned to 2 groups for comparison: group 1 – 12 patients, who received full-body “rapa” baths, inhalation phytoaromatherapy with a complex composition including phytoestrogens; group 2 – 14 patients, who received pelotherapy with applications of Saki lake mud on the «panty» zone and hydrodynamic phytoaromatic baths with a complex composition including phytoestrogens. Results. After therapy, a significant improvement of the parameters of climacteric disorders was noted in group 2. Severe disorders were practically absent in the second group – 2% (65 ± 6.1 scores), whereas mild changes prevailed – 64% (18 ± 5.3 scores). Changes in the microcirculation parameter were found, which increased by 19%, an increased contribution of endothelial oscillations to the total flux motion level, an increase of the amplitude of neurogenic and myogenic oscillations, a decrease of respiratory rates on average from 9.2 to 5.51 perf. units. In the first group, no significant changes were recorded. Conclusion. The use of pelotherapy in combination with hydrodynamic phytoaromatic baths permits to improve the parameters of microcirculation, venous and lymph output, trophism and oxygenation of tissues, and also ensures an adaptogenic effect. Key words: balneothaerpy, menopause transition, pelotherapy, rehabilitation
Influence of normal vaginal microbiota on papillomavirua infection
Authors:   Orenburg State Medical University, Orenburg, Russian Federation, Oleynik V.V. , Kremleva Е.А. ,   Orenburg State Medical University, Orenburg, Russian Federation, Sgibnev А.V. ,   Orenburg State Medical University, Orenburg, Russian Federation
Published: December 2020

Objective. To study the influence of normal vaginal microbiota on papillomavirus (HPV) infection. Patients and methods. We examined 160 women with HPV infection. We assessed the state of normal flora, the presence of sexually transmitted infections (STIs), and the HPV elimination rate. The correlation of living, apoptotic and necrotic epithelial cells depending on the levels of lactobacilli in native and stress-influenced specimens was studied in 140 HPV-positive and 20 HPV-negative patients. Results. We have found a stronger relation between HPV viral load and deficiency of lactobacilli (r = 0.498; р = 0.021) than between the former and the presence of STIs (r = 0.121; р = 0.072). High baseline levels of vaginal lactobacilli increase the likelihood of HPV elimination. Normal levels of lactobacilli enhance the survival of noninfected epithelial cells and reduce the levels of infected ones, which ensures a predominantly apoptotic form of cell death. HPV enhances the survival of infected cells and shifts the cell death structure toward necrosis. Conclusion. Lactobacilli counteract the influence of HPV on the vital conditions of vaginal epithelial cells. This accounts for better outcomes of HPV infection in patients with normal levels of flora. Key words: apoptosis, human papillomavirus, vagina, lactobacilli, cervix, epithelial cells
Use of endocervical trophoblasts in noninvasive prenatal testing for common aneuploidies
Authors:   N.P.Bochkov Research Centre for Medical Genetics, Moscow, Russian Federation, Musatova E.V. , Kapustina M.V. ,   Moscow Regional Research Institute of Obstetrics and Gynaecology, Moscow, Russian Federation, Minzhenkova M.E. ,   N.P.Bochkov Research Centre for Medical Genetics, Moscow, Russian Federation, Markova Zh.G. ,   N.P.Bochkov Research Centre for Medical Genetics, Moscow, Russian Federation, Tarlycheva A.A. ,   N.P.Bochkov Research Centre for Medical Genetics, Moscow, Russian Federation, Shilova N.V. ,   N.P.Bochkov Research Centre for Medical Genetics, Moscow, Russian Federation
Published: December 2020

The article presents an experience of isolation of trophoblast cells from cervical samples of pregnant women and demonstrates a possibility of determining aneuploid cells in cervical samples using FISH analysis. Objective. To study methods of effective isolation and reliable detection of trophoblasts for genetic pathology analysis. Patients and methods. The participants of the study were three pregnant women, who according to the findings of the combined first trimester screening test were referred to the group with a high risk for fetal aneuploidy. The terms of gestation varied from 12 to 14 wks. Immunocytochemical detection of trophoblast cells was performed with FITC-labelled HLA-G antibodies. FISH was performed with the use of locus-specific DNA probes on chromosomes 13/21 and a DNA probe on chromosome 18 centromere. The chromosome set of a fetus was verified by the results of standard cytogenetic analysis of semi-direct chromosome preparations from cytotrophoblast cells obtained by chorionic villi biopsy. Results. HLA-G-positive cells were found in all examined cytological specimens. FISH analysis with the use of DNA probes on chronomomes, whose trisomies are compatible with live birth, detected aneuploid cells in all three cases. Conclusion. The use of cervical trophoblasts for noninvasive collection of information about the genetic status of the developing fetus at present needs further study of effective and reliable methods of their isolation, detection and analysis. Key words: aneuploidy, throphoblast cells, NIPT, prenatal diagnosis, HLA-G
PENGEMBANGAN BAHAN AJAR BERBASIS HASIL RISET LAPANGAN PADA GURU-GURU SOSIOLOGI DAN ANTROPOLOGI SMA SE-SURAKARTA
Authors: Zuhri Saifuddin , Nurhadi Nurhadi , Trinugraha Yosafat Hermawan , Rahman Abdul , Pranawa Sigit , Nurcahyono Okta Hadi , Pudyastuti Septina Galih
Published: December 2020

Untuk meningkatkan kemampuan guru sosiologi di Kota Surakarta dalam hal pemanfataan teknologi pembelajaran serta pengembangan bahan ajar bagi peningkatan kualitas proses pembelajaran, grup riset Habitus mengadakan kegiatan pelatihan pengembangan bahan ajar berbasis hasil penelitian riset lapangan yang dilaksanakan pada hari selasa 28 Juli 2020 melalui pertemuan daring. Pelaksanaan kegiatan diisi dengan penyampaian materi terkait dengan Blended Leaning System dan Pengembangan bahan ajar berbasis penelitian. Dari hasil penelitian Riset Group kemudian dijadikan media dan sumber belajar baik secara visual maupun audio visual dengan sistem digital. Hasil dari pertemuan ini adanya luaran yang berupa website riset dari program studi pendidikan sosiologi antropologi FKIP UNS yang berisi hasil-hasil penelitian dari dosen dan mahasiswa serta video pembelajaran yang bisa dimanfaatkan sebagai bahan ajar bagi guru-guru sosiologi di Kota Surakarta.
 

Kata Kunci: bahan ajar, sosiologi, antropologi, dan hasil riset
Support Related to Schools and School Well-Being: Self Esteem as Mediator
Authors: Alwi Muhammmad Ahkam , Suminar Dewi Retno , Nawangsari Nur Ainy Fardana
Published: December 2020

School well-being is hope for students, they can survive in school. However, many students experience low levels of school well-being which has an impact on students' psychological and academic outcomes. The purpose of this study was to determine social support related to schools that can affect school well-being in high school students in Surabaya. The approach of this research is quantitative correlational study. Data collection using self-report questionnaires to measure school well-being, support related to schools, and self-esteem. Participants were 220 high school students. Path analysis procedures were performed to address the hypothesis.  The results found that the teacher's social support and friend social are related to direct and indirect school well-being mediated self-esteem. This study suggests that students can improve their well-being with support related to schools and self-esteem. Policymakers in schools, mainly school principals and teachers, can improve school well-being for students Limitations and implications of the findings are discussed for future research.

 

 

 
Information System of International Conference Management Based on Web
Authors: Sidiq Ahmad , Sujana Yudianto , Budianto Aris
Published: December 2020

Technological advances can be utilized to make information dissemination faster and more efficient. One example of the use of technology as a medium of information and management in the implementation of the conference is an information management system based on WEB. Based on the observations that have been conducted, found various problems, among others for the preparation of activity data reports, data participants, and so forth, actually already utilizing information technology, but still less effective. So many weaknesses that appear like; less effective and efficient in data processing, the time required for the preparation of reports long enough and the risk of error becomes large. Then from the side of presence also still printed manually. In addition, all the participants who register will be placed certificates, although the participants are not present in the conference, this happens because of the organizers difficult to sort out which participants are present and not present. In this article presented the feasibility test results of the conference management information system developed. Testing is performed on system experts, substance experts,   and users. Expert testing system using the instrument referring to ISO 9126 get 93% percentage. Expert testing of substance using instrument referring to ISO 9126 get 86% percentage.   While testing of users using the instruments that refer to ISO 9126 aspects of functionality gets an average percentage of 88.2%.
The Influence of Computer Literacy and The Use of The Website to Student’s Motivation in The Job Search Among Vocational Education Students
Authors: Anggun Dyah , Sucipto Taufiq Lilo Adi , Maryono Dwi
Published: December 2020

The objective of research were to find out (1) the influence of computer literacy toward student’s interest in looking for jobs; (2) the influence of website usage as media information toward student’s interest in looking for jobs; (3) The influence of computer literacy and intensity of website usage as media information toward student’s interest in looking for jobs of class XII vocational school at wonogiri district in academic year of 2015/2016.The research used quantitative approach with survey methods.The research used cluster random sampling with result 165 students in 3 district as the samples. Data were collected by questionnaire methods and documentation. The data analysis techniques used to test the hypothesis weresimple regression and multiple regression analysis.The result of this research as follow (1) there were positive and significant influence of computer literacy toward student’s interest in looking for jobs, with correlation coefficient (r) to 0,249 and thitung>ttabel (3,289>1,97); (2) there were a positive and significant influence of website usage as media information toward student’s interest in looking for jobs, with correlation coefficient (r) to 0,316 and thitung>ttabel (4,250>1,97); (3) there were positive and significant influence of computer literacy and intensity of website usage as media information toward student’s interest in looking for jobs of class XII vocational school at wonogiri district in academic year of 2015/2016, with correlation coefficient (r) to 0,361 and Fhitung>Ftabel (12,164>3,05). The magnitude of the influence of computer literacy and intensity of website usage as media information toward student’s interest in looking for jobs simultaneously obtained from the calculation of the R-square of 13%.
Development of Module and Augmented Reality Based Android Aplication Computer Assembly For Vocational High School Student
Authors: Maulana Muhammad Ardan , Sujana Yudianto , Budianto Aris
Published: December 2020

Based on observation in class X TKJ SMK Negeri 1 Sawit. Students had some problem when learning computer assembly. That happens because lack of equipment and learning media. They need a learning media that can be used to study computer assembly not only inside a school but outside as well. We propose to solve that problem with developing a new learning media that can help students learn independently. We develop a module and android based augmented reality application called ARRAKOM . when ARRAKOM detect a marker in the module. It can display a 3-dimensional model in real time. Learning media is created using ADDIE consist of Analysis, Design, Development, Implementation, and Evaluation. In the development stage, we are using an incremental model and created 2 prototypes of ARRAKOM. In result of the feasibility test, Arrakom gets measured with a Likert scale from expert media get percentage 75% very good, 25% good, 0% bad, 0% very bad. for expert material get percentage 57% very good, 43% good, 0% bad, 0% very bad. And from user get percentage 47% very good, 43% good, 3% bad and 0% very bad.
Implementation of Scratch Application to Improve Learning Outcomes and Student Motivation on Basic Programming Subjects
Authors: Permatasari Luthfi , Yuana Rosihan Ari , Maryono Dwi
Published: December 2020

This study aims to improve learning outcomes and student motivation on Basic Programming Learning by utilizing the Scratch application. Research begins with identifying problems that occur in the classroom. Then designed an action to overcome it in an action cycle. In this study giving of the action takes place in two cycles. Each cycle consists of planning, implementation, observation, and reflection. In cycle 1, learning is implemented using problem-based learning model, while in cycle 2 using project-based learning. The technique of data collection is done through comprehension test, observation of learning activity, assignment of portfolio, and interview to students and related teacher. Data analysis was done using quantitative and qualitative interactive analysis techniques. The results showed that the use of Scratch application can improve learning outcomes and student motivation. This is indicated by the percentage of the student’s learning outcomes completeness by 25.7% in pre-cycle, 71.4% in cycle 1, and 94.3% in cycle 2. While the percentage of student motivation is 40.3% in pre-cycle, 75.1% in cycle 1, and 83.9% on cycle 2.
Context-aware Smart Home Berbasis Internet of Things :	Tinjauan Pustaka
Authors: Chaizara Rezza Fariszal Hisyam , Budiyanto Cucuk
Published: December 2020

Setiap orang menginginkan keamanan dan kenyamanan di rumahnya, sebab keamanan dan kenyamanan hal yang sangat penting. Untuk itu diperlukan sebuah sistem keamanan untuk menjaga kenyamanan rumah dari tindakan pencurian, kebakaran, ataupun bahaya lainya yang dapat mengganggu keamanan dan kenyamanan rumah tersebut. Context Aware Smart Home merupakan istilah bagi smart home yang mempunyai kecerdasan untuk melakukan otomasi perangkat rumah berdasarkan konteks dari penghuni tersebut. Paper ini bertujuan mengevaluasi dua fitur utama smart home yaitu remote access dan home automation untuk menunjang context aware smart home systems. Artikel ini disusun dengan menerapkan metode analisis kritis terhadap literatur yang dipublikasikan sejak 2006 hingga 2018 dalam jurnal maupun prosiding berbahasa Indonesia dan Inggris. Sebagai tindak lanjut penelitian di masa depan, artikel ini mengusulkan dikembangkannya rancangan sistem smart home berbasis Internet of Things yang menjadi solusi menjaga keamanan dan kenyamanan rumah. Berbagai fitur perancangan ini mempertimbangkan kapabilitas Wemos sebagai pengontrol utama sistem context-aware smart home.

Kata Kunci : Context-aware smart home, Internet of Thing
PENGARUH PENDEKATAN DISCOVERY LEARNING TERHADAP KEAKTIFAN DAN HASIL BELAJAR PESERTA DIDIK KELAS X SMK NEGERI 1 KARANGANYAR DALAM OPERASI PERHITUNGAN MATEMATIKA
Authors: Attaufiq Yugo
Published: December 2020

A This classroom action research was conducted in Class X Multimedia 4 with a total of 35 students. The objectives to be achieved in this study were to determine the process of implementing learning in increasing the activeness of class X students of SMK Negeri 1 Karanganyar in applying mathematical calculation operations. Increasing the activeness of implementing mathematical calculation operations for class X students of SMK Negeri 1 Karanganyar after participating in learning with the Discovery Learning model. Improved learning outcomes of class X SMK Negeri 1 Karanganyar after participating in learning with the Discovery Learning model. The technique used in this research is to make structured observations / observations in CAR-based learning activities. From the research that has been carried out, the results of the observations indicate that 22 out of 30 students (74%) seem to be active in the learning process. The scores of students resulting from the written test evaluation were only 7 students (24%) who still had not reached the KKM (minimum completeness criteria).
The impact of armed conflict on economic performance and enterprise value in the country
Authors:   Moscow City Pedagogical University, Frolov Yury , Bosenko Timur ,   Moscow City Pedagogical University
Published: December 2020

The intensity of armed conflicts has peaked in the past 30 years over the past two centuries. The problems of war emergence affect not only social indicators, but also economic and legal aspects of existence of enterprises within the framework of unstable situation in the country. Even in such a difficult time, enterprises at various levels are trying to develop despite the falling economic and social indicators of the local economy. Over time, in places where local armed conflicts have turned into frozen ones (e.g. Transnistria, Gaza Strip, Syria), enterprises have learned to exist in unstable conditions, forming new strategies and reactions to events. Before the World War II, researchers did not question that there was a connection between the decline in the economic performance of enterprises and the conduct of war or armed conflict in a country. However, the number of studies on this issue is small, which makes this paper relevant in the process of studying the issue. The analysis of experience of functioning of business in conditions of war can be useful for thec enterprises of various industries. The purpose of the paper consists in research of influence of local armed conflicts on cost of the enterprises in the country.
Relation of technology and urbanization with electricity consumption in Kazakhstan
Authors:   Kazakh-German University, Tleppayev Arsen , Zeinolla Saule ,   Academy of Public Administration under the President of the Republic of Kazakhstan
Published: December 2020

We analyze the impact of social, economic and technical factors on power consumption in Kazakhstan. The work uses time series cointegration equation with the Granger causality test for data 1993-2019. The results show that urbanization, income levels and technology levels affect electricity consumption in the long term. Urbanization and economic growth have a strong impact on growth in electricity consumption. In the article, the influence of growth of digital technologies use which can have bi-directional influence on the energy consumption is analyzed. In the long term, the development of digital technologies in Kazakhstan reduces the need for electricity through the use of energy-saving measures. Digitalization should stimulate the efficiency of energy systems by optimizing consumption and metering, reducing losses, generating with the lowest costs and emissions, etc.