bluuebunny/crossref_metadata_2025 huggingface dataset:
Arbeitsschutz „im Huckepack“ – ein alternatives Konzept zur Ansprache von Unternehmen auf Sicherheits- und Gesundheitsthemen. Teil II: Erprobung in einer Maßnahme für Kleinunternehmen
Authors:   Hochschule der Wirtschaft für Management, Mannheim, Zimber Andreas , Horchler Julika ,   Hochschule der Wirtschaft für Management, Mannheim, Weiser Imke ,   Hochschule der Wirtschaft für Management, Mannheim, Gregersen Sabine ,   Berufsgenossenschaft für Gesundheitsdienst und Wohlfahrtspflege (BGW), Hamburg, Prüße Martin ,   BG Holz und Metall, Hannover, Schmitt-Howe Britta ,   Bundesanstalt für Arbeitsschutz und Arbeitsmedizin (BAuA), Berlin, Pietrzyk Ulrike ,   Arbeitsgruppe Wissen-Denken-Handeln, Technische Universität Dresden, Cosmar Marlen ,   Institut für Arbeit und Gesundheit der DGUV, Berlin
Published: September 2023

Occupational safety “piggybacked” – an alternative concept for addressing companies with safety and health issues. Part II: Implementation in a measure for small businesses Background: Entrepreneurs in small businesses represent a challenging but also underestimated target group for occupational safety and health (OSH) prevention activities. Objective: Referring to the article published in ASU 6/2023 on the theoretical foundation of the “piggyback method”, an alternative concept for addressing small business owners on OSH issues is being developed and implemented. Method: OSH issues were linked by content to topics preferred by the target group and presented according to the principles of second-order conditioning. The interactive events were marketed by two chambers and evaluated by an online survey with a random sample of n = 40. Results: The procedure and implementation were rated positively overall by the participants. The OSH issues (target stimulus) were rated as just as relevant as the lack of skilled workers and self-care (context stimuli). Conclusions: The results speak for the usefulness of the “piggyback method” for OSH prevention activities. However, the results are not sufficient as a proof of effectiveness; this requires further practical tests and evaluations. Keywords: occupational safety and health – small businesses – entrepreneurs – evaluation
Berufliche Wiedereingliederung nach COVID-19 aus Sicht der gesetzlichen Unfallversicherung
Authors:   Abteilung Arbeitsmedizin, Gefahrstoffe, Gesundheitswissenschaften (AGG), Berufsgenossenschaft für Gesundheitsdienst und Wohlfahrtspflege (BGW), Hamburg, Nienhaus Albert
Published: September 2023

Die gesetzliche Unfallversicherung (GUV) hat den Auftrag, zur Verhütung von Arbeits- und Wegeunfällen sowie Berufskrankheiten beizutragen. Nach einem Unfall oder nach der Entstehung einer Berufskrankheit ist es Aufgabe der GUV, mit allen geeigneten Mitteln die Gesundheit und Leistungsfähigkeit der betroffenen Person wiederherzustellen oder, falls das nicht möglich ist, den bestmöglichen Zustand durch entsprechende medizinische Behandlung einschließlich Rehamaßnahmen anzustreben. Dabei ist es das Ziel, eine möglichst ungehinderte oder, falls das nicht möglich ist, eine möglichst gute berufliche und soziale Teilhabe zu erreichen. Geregelt ist dies im Sozialgesetzbuch (SGB) VII sowie, bezogen auf die Teilhabe, im SGB IX.
Chancen erschließen: Die wichtige Rolle der beruflichen Rehabilitation bei der Fachkräftesicherung
Authors:   Bundesagentur für Arbeit, Nürnberg, Scherm Beate
Published: September 2023

Der Beitrag soll einen kurzen Einblick in das komplexe System der beruflichen Rehabilitation allgemein und in der Bundesagentur für Arbeit (BA) im Besonderen geben. Dabei sollen überblicksartig die Beratungs- und Dienstleistungsangebote der BA, aber auch einige Herausforderungen vorgestellt werden. Denn: Ein inklusiver Arbeitsmarkt bleibt das wichtigste Fundament für eine inklusive Gesellschaft.
ZİRKONYA GÜNCEL JENERASYONLARI: KLİNİK İPUÇLARI
Authors: DENİZ Diler , AKTAŞ Güliz
Published: September 2023

Tam seramik restorasyonlar yıllardır diş hekimleri tarafından güvenle tercih edilen restorasyon çeşitlerindendir. Ancak hastaların seans sayısı ve süresinin kısalması ile birlikte artan estetik beklentisi, diş hekimliğinde dijital teknoloji kullanımının önemini artırmıştır. Güncel klinik uygulamalarda dijital diş hekimliğinin kullanımıyla birlikte, monolitik tam seramik restorasyonlara yönelim her geçen gün hızlanmaktadır. Bu talebe karşılık, üretici firmalar da içeriği ve özellikleri geliştirilmiş yeni materyalleri dental markete sunmaktadır. Özellikle yüksek estetik ve aynı zamanda mekanik dayanıklılığa sahip materyaller geliştirilmeye devam etmektedir. Zirkonya restorasyonlar yıllardır yüksek kırılma dayanım ve biyouyumluluk özellikleri nedeniyle tercih edilse de porselen-zirkonya bağlantısının zayıf olması (potansiyel chipping riski) ve nispeten düşük estetik (translusensi ve ışık geçirgenliği) özellikleri nedeniyle geliştirilmeye en açık restorasyon materyallerindendir. Zirkonyanın bu dezavantajlarını ortadan kaldırmak ve avantajlarından faydalanabilmek amacıyla üreticiler, zirkonyanın içyapısında değişiklikler yaparak monolitik kullanıma uygun hale getirmişlerdir. Ancak güncel kullanımda çok çeşitli monolitik zirkonya blokların bulunması, klinisyenin uygun materyal seçiminde zorluklar oluşturmaktadır. Bu derlemenin amacı klinisyenlere rehber olacak şekilde güncel monolitik zirkonya materyalinin sınıflandırmasını yapmaktır.
O envolvimento parental durante a pandemia covid-19: Perceções e crenças dos pais em Portugal
Authors: Almeida Ana Patrícia , Pacheco Patrícia
Published: September 2023

O papel dos pais na educação dos filhos é crucial para o sucesso educativo das crianças e tem benefícios para todos os intervenientes (pais, professores, profissionais, crianças).O contexto atual da pandemia covid-19 mudou a forma como os pais se envolvem e participam na escola, revelando uma diversidade de práticas. Estas são orientadas pelas perceções e crenças que os pais têm sobre a sua participação e sobre as suas competências, bem como pelas vantagens e obstáculos que atribuem ao seu envolvimento. Assim sendo, procurou-se com o estudo que aqui se apresenta: 1) Caracterizar as perceções dos pais sobre o seu envolvimento na escola durante a pandemia covid-19, nomeadamente na fase de distanciamento social e de ensino remoto de emergência; 2) Identificar os benefícios e obstáculos sobre o seu envolvimento e a relação escola/família; 3) Caracterizar as crenças de autoeficácia dos pais portugueses sobre o seu papel na fase dedistanciamento social e de ensino remoto de emergência. Neste estudo participaram 106 pais de crianças a frequentar os 1º e 2º ciclos do Ensino Básico. Para a recolha de dados foi utilizado um questionário com 29 questões. De forma global, os resultados indicaram que: os pais referem uma diversidade de obstáculos que remetem para barreiras pragmáticas, culturais e psicológicas; as novas tecnologias foram essenciais para a comunicação escola/famílias; houve uma diversidade de respostas a nível da gestão do tempo das tarefas escolares e familiares; assim mesmo, a maioria dos pais referiu a existência de desgaste emocional e social, realçando o afastamento dos amigos e outros familiares.
La inclusión de estudiantes indígenas y sus resultados escolares: percepción docente
Authors: Meléndez Grijalva Perla , Carrera Hernández Celia , Madrigal Luna Josefina , Lara García Yolanda Isaura
Published: September 2023

El estudio ofrece los resultados de una investigación de tipo fenomenológico que tuvo como propósito indagar las experiencias y percepciones de 70 profesoras y profesores frente a grupo en la ciudad de Chihuahua, sobre la inclusión y los resultados escolares de estudiantes indígenas, así como la pertinencia que tienen desde sus experiencias, para atenderles mediante el Nuevo Modelo Educativo en México. Se utilizó cuestionario, entrevista y grupo focal, donde se triangularon los datos, teniendo como resultados que las principales dificultades que enfrentan estudiantes indígenas son la comunicación, contenidos no significativos, problemas emocionales y dificultad para socializar. Así mismo, los profesores y profesoras manifiestan dificultades pedagógicas, organizativas e institucionales, necesidades de formación y actualización, sintiéndose ajenos a las reformas educativas; de esta forma, se observa bajas expectativas hacia esta población estudiantil. Finalmente, se concluye que las actuales políticas educativas sustentadas en inclusión social y multiculturalismo son insuficientes, los resultados escolares siguen siendo los más bajos y se mantienen estereotipos negativos y prejuicios hacia los estudiantes indígenas.
Evaluación de temas controversiales. El caso chileno de la ocupación de la Araucanía
Authors: Llancavil Llancavil Daniel , Montanares Vargas Elizabeth , González-Marilicán Matías , Vásquez Leyton Gabriela
Published: September 2023

La finalidad de este artículo de investigación es analizar las prácticas evaluativas del profesorado de Historia, Geografía y Ciencias Sociales, de la Región de la Araucanía, al evaluar la ocupación del territorio como tema controversial. Dicha temática es atingente, puesto que su tratamiento contribuye a la formación de estudiantes y profesores abiertos al diálogo y dispuestos a construir puentes que acerquen posiciones entre los diversos actores de este territorio, de modo contribuir a la paz social en la región. Este estudio se enmarca en una metodología de carácter cualitativa y descriptiva, bajo un diseño de estudio de caso instrumental. Para el análisis de datos, obtenidos de las entrevistas a 23 profesores de la región y la revisión de sus herramientas de evaluación, se agrupó la información en categorías y subcategorías con sus correspondientes evidencias. De esta forma, los resultados de este estudio evidencian que el profesorado utiliza, como estrategias de evaluación, el trabajo con fuentes, la investigación, la exposición oral y escrita, así como el debate. Además, que los conocimientos y habilidades evaluados corresponden a las establecidas por el currículo escolar y que otros saberes a evaluar emergen del contexto educativo donde se emplaza esta investigación. Finalmente, los hallazgos nos permiten sostener que los docentes de este estudio comienzan a incorporar prácticas evaluativas innovadoras y centradas en el aprendizaje de los estudiantes.
Role of BA and IAA on regeneration and shoot proliferation in vitro of three strawberry (Fragaria x ananassa Duch.) varieties
Authors: Gonzales-Arteaga Javier J. , Rodríguez-Layza Juan , Romero-Rivas Ladislao C. , Párraga-Quintanilla Adelmo , Olivera-Soto Julio A.
Published: September 2023

The objective was to determine the response of three strawberrry varieties (Fragaria x ananassa Duch.) to the aplication of two plant growth regulators: indol acetic acid (IAA) and 6-Benzyl aminopurine (BAP) added to Murashige & Skoog médium in strawberry micropropagation. The complete randomized block design was used and three strawberry varieties ‘Aromas’, ‘Albion’ and ‘Camarosa’ were considered as trials. MS medium for shoot regeneration in initial stage was supplemented with BAP 0.5 mgL-1 and IAA 0.6 mgL-1. Shoot proliferation MS medium was supplemented with BAP 0.5 mgL-1 in multiplication stage and MS medium hormone free was used for rooting induction. It was determined that after 32 days of cultivation the combination of IAA and BAP significantly affected shoot regeneration of apical shoot tips of three strawberry varieties. The greatest effect was caused on ‘Camarosa’. In addition, results on shoot multiplication using BAP indicated that ‘Albion’ performed better in shoot proliferation in terms of shoots per explants reaching 2.51 compared to ‘Camarosa’ and ‘Aromas’ with significant differences. However rooting medium with no growth regulators improves root development with best response of ‘Camarosa’ root length reaching 4.76 cm.
Technological and sensory characteristics of sweet biscuits with the addition of tocosh flour (Solarium tuberosum) and tarwi flour (Lupinus mutabilis)
Authors: Quineche-Adrian Ursula Susana , Paucar-Menacho Luz Maria
Published: September 2023

The objective of this study was to determine the technological and sensory characteristics of sweet biscuits with the addition of tocosh flour and tarwi flour. For which a rotational compound central design (DCCR) 22 was used, giving a total of 11 formulations (4 factorial, 4 axial and 3 central points) where the independent variables were X1 = Tocosh flour and X2 = Tarwi flour with additions of X1 from 2% to 8% and X2 from 2% to 6% replacing the percentage of wheat flour in the base formulation. The results show that the F5 (2% X1 and 4% X2) is the one that presented the highest value in its sensory evaluation. Likewise, it presented a higher percentage of protein (8.48%) in relation to the biscuit without substitution (8.25%). The best formulation was determined by multiple response optimization (desirability), obtaining an optimal sponge cake with 3.22% X1 and 4.55% X2 replacement of wheat flour, resulting in a sponge cake with moisture (23.99 ± 0.16%), protein (8.65 ± 0.18%), fat (6.42 ± 0.70%), ashes (0.51 ± 0.08%), total dietary fiber (6.30 ± 1.70%) and carbohydrates (54.80 ± 1.44%).
О возможности автоматизированной оценки видеоинтервью по лицевым экспрессиям
Authors:   Московский государственный университет им. М. В. Ломоносова, Москва, Россия, Гусев Алексей , Баев Михаил ,   Санкт-Петербург, Россия, Мачужак Анастасия ,   Группа НЛМК, Москва, Россия, Подрезова Александра ,   Группа НЛМК, Москва, Россия
Published: September 2023

Цель исследования — обосновать возможность использования лицевых экспрессий для автоматизированного и дистанционного анализа видеоинтервью для оценки персонала. Дизайн исследования предполагает сопоставление разработанных авторами показателей мимической активности для оценки кадрового видеоинтервью с соответствующими оценками специалистов по управлению персоналом. Общая методология исследования основана на возможности перехода от измерения мимической активности к анализу эмоционального поведения человека и далее — от анализа эмоций к пониманию смыслов, от понимания смыслов к оценке личности сотрудника, отвечающего на вопросы интервью. Частная методология основана на разработанном М. С. Баевым и А. Н. Гусевым прямом подходе к анализу двигательных единиц системы кодирования лицевых движений по видеозаписи и использовании их для оценки эмоционального состояния человека. Сотрудники крупных российских компаний (413 мужчин и 242 женщины, средний возраст = 42,6 года) дистанционно проходили стандартизированное видеоинтервью, включавшее от шести до 16 вопросов. Результаты. Для анализа было отобрано 4038 видеозаписей. Анализ мимической активности выполнялся с помощью ПО ЭмоРадар WR 5.0 путём выделения отдельных двигательных единиц, базовых эмоций и паттернов мимической активности. На основании критериев, предложенных специалистами по управлению персоналом, были разработаны шесть правил автоматического анализа мимической активности респондентов на основании появления на видеозаписи паттернов двигательных единиц, характеризующих поведение респондента при ответе на вопрос интервью как соответствующее / несоответствующее ожиданию эксперта. Для сравнительного анализа отобрано 60 видеозаписей, которые были оценены шестью экспертами по шкалам: включённость, стресс, уверенность, лёгкость, активность, сила. Полученные результаты свидетельствуют о хорошем соответствии итогов автоматизированной классификации видеозаписей на основе анализа мимической активности респондентов и оценок экспертов по шкалам. Значение для практики. Таким образом, подтверждена возможность практического использования разработанной нами оригинальной технологии автоматического анализа мимической активности и построенного на её основе алгоритма оценивания дистанционно записанных ответов респондентов на вопросы кадрового видеоинтервью, что расширяет методические возможностей специалистов по управлению персоналом при работе с большими объёмами видеоинтервью.
Методика трансформации кадрового потенциала научно-исследовательского института машиностроительного предприятия
Authors:   Университет науки и технологий МИСИС, Москва, Россия, Митенков Алексей , Тихонова-Быкодорова Ирина ,   Университет науки и технологий МИСИС, Москва, Россия
Published: September 2023

Цель. В научно-практической статье авторами апробируется методика трансформации кадрового потенциала научного-исследовательского коллектива крупного промышленного предприятия с многолетней историей и уникальной конструкторско-технологической экспертизой. Методология. В рамках работы раскрыты основные подходы и этапы по организации проекта трансформации кадрового потенциала. В ходе стратификации были сформированы три группы сотрудников для анализа и построения унифицированных принципов дальнейшей трансформации. В состав дорожной карты проекта были включены три крупных этапа: 1) персональная диагностика — оценка кадрового потенциала сотрудников НИИ; 2) треки — определение кадровых треков ключевых сотрудников НИИ и групп; 3) мотивация — разработка системы мотивации сотрудников НИИ, включающая программу развития и обучения и общую программу внедрения ценностей. Авторами приведён ряд новшеств в практических подходах к работе и формированию потенциала коллективов научных и конструкторских групп специалистов крупных предприятий машиностроительного сегмента Российской промышленности. Ценность результатов. Задача долгосрочного повышения производительности труда научно-конструкторских работников промышленного машиностроительного предприятия нетривиальна в силу двух аспектов: высокой экспертности труда специалистов (причём ряд из них обладает уникальными знаниями и компетенциями) и сложности в объективном измерении реального результата труда (НИОКР, чертёж, расчёт, конструкторское решение). Разработанная авторами методика организационной трансформации может быть использована другими участниками отрасли, как надёжный инструмент последовательного совершенствования кадрового потенциала на предприятиях машиностроения в части сотрудников научных и конструкторских подразделений с целью повышения производительности их труда и вовлечённости как в краткосрочной, так и в долгосрочной перспективе.
Психическая саморегуляция как ресурс сохранения профессионального здоровья
Authors:   Санкт-Петербургский государственный университет,  Санкт-Петербург, Россия, Гофман Ольга , Банаян Алексанжра ,   Научно-исследовательский институт физической культуры,  Санкт-Петербург, Россия
Published: September 2023

Тема сохранения профессионального здоровья на разных этапах профессионализации крайне актуальна, особенно в процессе обучения и подготовки к трудовой деятельности, когда механизмы заботы о себе только формируются. В статье представлены результаты исследования психофизиологического состояния учащихся и их способности к психической саморегуляции. Цель исследования: изучить особенности психической саморегуляции будущих педагогов в сфере физической культуры и спорта на основе сравнения объективных и субъективных показателей. Дизайн исследования. Выборка включала 104 студента в возрасте 17–20 лет различной спортивной квалификации. Методы исследования: метод газоразрядной визуализации, метод кожно-гальванической реакции и батарея психологических тестов. Выводы. 1. Благоприятные значения психофизиологического состояния определены только у 3% студентов, у 53% — средние, и у 44% — неблагоприятные; выявлены высокие показатели психического напряжения (Фон 8,27 ± 6,97, МкСим), низкая выраженность навыка психической саморегуляции. 2. Выявлено рассогласование значений аппаратной диагностики и результатов психологического тестирования, что свидетельствует о неумении учащихся корректно определять своё психическое состояние и неспособность им управлять. 3. Выявлено девять барьеров здорового поведения, возникновение которых связано с такими индивидуально-психологическими особенностями, как психическая саморегуляция и представления о себе. Обнаружена позитивная динамика изменения субъективных представлений о состоянии собственного здоровья в целом в различных временных локусах. 4. Качество психофизиологического состояния имеет непосредственную связь с состоянием здоровья в целом, представлениями о барьерах здорового поведения, выбором проактивных стратегий совладания (прежде всего, «самоконтроль»), самооценкой текущего состояния и способностей к расслаблению или активации. 5. Определены предикторы психофизиологического состояния: представление о состоянии здоровья в целом, психическом здоровье в настоящем, стратегии совладания «самоконтроль» и «конфронтация», уровень информированности о здоровье и сформированное в прошлом представление о собственном состоянии здоровья. Таким образом, гипотеза исследования о том, что будущие педагоги физической культуры, занимающиеся спортом, обладают хорошо выраженной способностью дифференцировать своё психоэмоциональное состояние и умеют управлять им в заданный период времени не подтвердилась. Практическая значимость. Даны рекомендации по формированию навыка психической саморегуляции.
NOCA (Ischemia with Non-Obstructive Coronary Arteries) e MINOCA (Myocardial Infarction with Non-Obstructive Coronary Arteries) Il ruolo della risonanza magnetica cardiaca
Authors: Vinco Giulia
Published: September 2023

Una percentuale non trascurabile di pazienti sottoposti a studio coronarografico, sia in condizioni elettive che in regime di urgenza, dimostrano coronarie normali o assenza di coronaropatia ostruttiva. Questo riscontro ha portato negli ultimi anni al riconoscimento di due condizioni: l’ischemia in assenza di malattia ostruttiva coronarica (INOCA), che trova una base patogenetica nella disfunzione coronarica microvascolare o nell’angina vasospastica; e l’infarto miocardico a coronarie indenni (MINOCA), una diagnosi operativa che include molteplici possibili meccanismi patogenetici. Le attuali linee guida indicano l’importanza di una corretta identificazione di queste due entità spesso trascurate, tramite un approccio standardizzato che include l’imaging multimodale, portando a chiarire l’eziologia sottostante e quindi il corretto trattamento. In questo contesto il ruolo della risonanza magnetica cardiaca (RMC) appare cruciale ed è indicata in tutti i pazienti con MINOCA, in assenza di una evidente causa sottostante. La RMC riveste un ruolo primario nella conferma diagnostica e nella diagnosi differenziale: è difatti in grado di identificare la causa sottostante nell’87% dei pazienti con MINOCA grazie alla caratterizzazione tissutale tramite late gadolinium enhancement (LGE). Anche nei pazienti con INOCA la RM cardiaca è molto utile in quanto permette di valutare la presenza di ischemia miocardica e disfunzione coronarica microvascolare.
Cardiopatia ischemica senza aterosclerosi coronarica ostruttiva. Ci dobbiamo stupire? Riflessioni su INOCA (Ischemia with Non-Obstructive Coronary Arteries) e MINOCA (Myocardial Infarction with Non-Obstructive Coronary Arteries)
Authors: Orsini Enrico
Published: September 2023

Le sindromi miocardiche ischemiche rappresentano un gruppo di patologie cardiache sostenute da cause molteplici e con una espressione clinica estremamente variabile, che condividono un unico elemento comune: l’ischemia miocardica. L’ostruzione aterosclerotica delle arterie coronariche, anche se costituisce una causa importante di ischemia, non è sufficiente a spiegare globalmente la sindrome ischemica, sia nelle forme croniche, sia nelle forme acute. Molti meccanismi funzionali, di natura macrovascolare, microvascolare e non vascolare concorrono in misura variabile alla patogenesi della sindrome. Fra i pazienti con sindromi miocardiche ischemiche croniche, INOCA (Ischemia with Non-Obstructive Coronary Arteries) ha una prevalenza del 33% nei maschi e del 65% nelle femmine. MINOCA (Myocardial Infarction with Non-Obstructive Coronary Arteries) rappresenta il 5-15% di tutte le forme di infarto miocardico acuto. I pazienti con INOCA e MINOCA costituiscono una sfida diagnostica e terapeutica per il cardiologo in quanto spesso non ricevono una diagnosi e sono sottotrattati. Le indagini diagnostiche per accertare i meccanismi ischemici individuali sono essenziali, allo scopo di istituire un trattamento personalizzato. La sovrapposizione fra coronaropatia ostruttiva con i meccanismi alla base di INOCA/MINOCA può condurre a trattare inutilmente stenosi coronariche funzionalmente non ischemizzanti, contribuendo alla persistenza/ricorrenza dei sintomi e alla cattiva qualità di vita di questi pazienti.
Recent Issues and Regulatory Requirements of Data Integrity in Pharmaceutical Industry
Authors:   The Pharmaceutical Society Of Korea, Choi Woung , Kim Min , Na Dong Hee
Published: September 2023

Pharmaceutical manufacturers are responsible for providing safe and effective high-quality products to patients and consumers by assuring that decisions on production and distribution of products are based on accurate, reliable, truthful, and complete data. Nevertheless, in recent years, regulatory authorities have increasingly observed good manufacturing practice (GMP) violations related to data integrity during GMP inspections. This is problematic since ensuring data integrity is a mandatory requirement to assure the safety, efficacy, and quality of drug products. The breaches in data integrity found during inspections have set off the need to publish more detailed guidance documents that describe more clearly the regulatory expectations in GMP-related systems. With new awareness derived from recent regulatory restrictions, industry uses state-of-the-art technology to improve processes and establish systems for detection and mitigation of gaps that affect data integrity in paper and computerized systems. Recently issued guidances by regulatory agencies emphasize the importance of good laboratory and manufacturing documentation practices. The main purpose of regulatory requirements remains confident in the quality and integrity of the data generated to ensure patient safety and product quality. This review summarizes data integrity guidances and risk assessment that facilitate firms to develop robust data integrity management system with both manual processes with paper records and computerized systems.
Analysis of Medical and Pharmaceutical Expenses for Lung Cancer Before and After the Introduction of Immunotherapy
Authors:   The Pharmaceutical Society Of Korea, Jeon Seongmi , Park Mi-Hai
Published: September 2023

Lung cancer has been the leading cause of cancer-related deaths in Korea and is considered one of the world’s most costly cancer to treat. Novel insights into the molecular biology of lung cancer discovered in recent years have facilitated the use of targeted therapy and immunotherapy, arousing concerns over the financial burden of patients due to high healthcare costs. Using HIRA-NPS (Health Insurance Review & Assessment Service-National Patient Sample) database from 2015 to 2020, we analyzed lung cancer patients’ both medical and pharmaceutical expenditures. This study focused on targeted therapies and immunotherapies and compared these expenditures before and after the introduction of immunotherapy. In our analysis, the number of patients prescribed targeted drugs and immunotherapies for lung cancer continues to increase yearly, and consequentially pharmaceutical expenses are also on the rise. An interrupted time series analysis showed pharmaceutical expenditures for lung cancer increased immediately after the introduction of immunotherapy and have continued to increase since then, while total medical expenses, medical and pharmaceutical expenses per patient have not shown any further increase after the immediate increase. The number of patients in immunotherapy has increased but there is little change in drug prices, such as drug price cuts or the entry of more expensive drugs, so the spending per patient has not consistently increased.
Exploring COVID-19 Arabic Humorous Comments in Social Media: Linguistic Analysis of Facebook Comments Using the General Theory of Verbal Humor
Authors: Alkaraki Sulaiman M. , Maros Marlyna , Alias Norhayati Binti
Published: September 2023

This paper investigates the Arabic verbal humorous comments pertaining to COVID-19 on social media. The main objectives of the paper are to identify the distinct categories that are highlighted in those comments disseminated between March and September 2020, on the AlMamlaka and Roya Jordanian Facebook accounts. Additionally, the study examines the claim of Attardo and Raskins's (1991) that the "target" is an optional Knowledge Resource in the General Theory of Verbal Humor. The research design employed in this study is descriptive qualitative. The researchers conducted a thematic analysis to analyze 15 comments, applying the General Theory of Verbal Humor of Attardo and Raskin (1991). The analysis revealed eight emerging categories: governmental, gender, COVID-19, lockdown, behavior, conspiracy, geographical, and facemask jokes. The study found that humorous comments conform to the six Knowledge Resources of the General Theory of Verbal Humor. The most prominent logical mechanism used in the comments was irony and sarcasm, enabling Jordanians to shed light on hidden issues to express their reactions and feelings. The study also found that identifying the target in a humorous comment is crucial in determining the various categories of humorous comments. The research opens avenues for further exploration into the utilization and interpretation of humor in diverse cultural settings, during other natural disasters, and its impact on understanding humorous content.
SUPERVISI AKADEMIK UNTUK MENINGKATKAN KOMPETENSI GURU SDN SANTAKA KECAMATAN CIMANGGUNG DALAM MELAKSANAKAN STANDAR PROSES TAHUN PELAJARAN 2018/2019
Authors: Karwati Wawat
Published: September 2023

Supervisi merupakan salah satu kompetensi yang harus dimiliki oleh kepala sekolah dalam menjamin kualitas proses pendidikan dan pembelajaran di sekolah. Kenyataan di lapangan menunjukan kompetensi guru dalam melaksanakan standar proses belum sepenuhnya memuaskan. Supervisi akademik yang dilaksanakan dengan objektif dan transparan dapat dijadikan solusi terhadap permasalahan tersebut. Hasil penelitian menunjukan bahwa kemampuan guru dalam melaksanakn standar proses meningkat signifikan antara siklus 1 dan siklus 2. Di samping itu, guru juga memperlihatkan respon positif terhadap kegiatan supervise akademik. Supervise is one of several competencies that should be mastered by principals to guarantee the quality of educational and teaching learning process. In fact, in the real situation, teachres’ competencies in doing the standard of process, have not been satisfying enough. Academical supervision that is carried out objectively and trasparantly can be a solution to the problem. The research result showed that teachers’ competencies in doing the standard of process increased significantly between cycle 1 and cycle 2. Besides, teachers showed positive response to the academical supervision.
ANALISIS BUKU: KEUTUHAN TAHAPAN PEMBELAJARAN IPA DENGAN PENDEKATAN SAINTIFIK PADA BUKU SISWA SEKOLAH DASAR KURIKULUM 2013
Authors: Limiansih Kintan
Published: September 2023

This study aimed to know the integrity of the learning stages with a scientific approach in the book of elementary school students curriculum specialized in the field of IPA 2013. Analysis of the book is based on the importance of a scientific approach to development, the importance of books as learning guides, and previous research gaps. This research is a descriptive research in which researchers describe the activities in the book according to the facts. The books that analyzed are primary student books grade 1, 2, 3, 4 and 5. Analyses were performed by using the instrument of accession rubric analysis that has been processed by researchers. From the analysis, obtained information that, there are no activites in science which apply the learning stages with the full scientific approach intact (5 stages). So this book must be repaired by the goverment ant teacher. Besides that, teachers need to do additional activities in order to maximize learning with scientific approach.
Pengembangan Pembelajaran Seni Musik di Sekolah Dasar Melalui Pelatihan Notasi Ritmik Tuwagapat
Authors: Magistra Ari Arasy , Jumhana Nana , Robandi Babang , Giwangsa Sendi Fauzi , Rahmawati Evi , Murron Faisal Saddam , Amalia Elsa
Published: September 2023

This research aims to train teachers in reading and writing notation, therefore tuwagapat notation is given and made with the hope that it can solve problems that arise in learning music in elementary schools, especially on notation material This training uses a qualitative descriptive method. Based on the results of the research and discussion that has been done, it can be concluded that the Tuwagapat Training can improve the ability to write and read rhythmic notation as an alternative in developing easy and fun music learning. The results were 80% of the training participants getting the very good category and 20% in the good category in the aspect of reading  rhythmic notation while in the aspect of writing  rhythmic notation there were 70% of the training participants got the very good category and 30% is in the good category.
Penggunaan Media Benda Asli untuk Meningkatkan Prestasi Belajar Matematika Siswa SD
Authors: Soelastri Ida
Published: September 2023

During mathematics learning, the real world is only used as a place to apply concepts. Students have difficulty learning mathematics in class. As a result, students do not appreciate or understand mathematical concepts and have difficulty applying mathematics in everyday life. This study aims to determine how the use of real object media can improve student achievement in learning mathematics in elementary school. The method used is a qualitative method with a Class Action Research (CAR) design. The instruments used include observation sheets, tests, questionnaires and attitude scales. Based on the research and discussion results, it can be concluded that the improvement of student achievement in Mathematics subject on the subject of spatial construction through the use of Original Objects media.
La fritura de los alimentos: pérdida y ganancia de nutrientes en los alimentos fritos
Authors: Suaterna Hurtado Adriana Cecilia
Published: September 2023

La fritura es uno de los métodos de cocción más simples. Consiste en calentar aceite o grasa comestible entre 160 y 180°C e introducir el alimento para su cocción. Este método se caracteriza por formar una “costra” en la superficie del alimento y generar un sabor característico, agradable. Durante la fritura se presentan cambios en la composición nutricional de los alimentos, estos dependen del tipo de grasa, de las características propias del alimento, del tiempo, la temperatura y demás condiciones del proceso. Entre los cambios que más comúnmente se presentan está el aumento en el contenido de la grasa total o disminución, en el caso de los alimentos ricos en ésta con una tendencia similar al aceite o grasa utilizado. Con relación al contenido de vitaminas y minerales, las pérdidas de estos componentes son menores cuando se compara el método de fritura con otros métodos de cocción, debido a la rapidez del proceso. Durante el proceso de fritura también ocurren cambios indeseables como la formación de oxiesteroles por oxidación del colesterol cuando se fríen alimentos de origen animal o en grasa animal, y formación de acrilamidas, ambos compuestos relacionados con el aumento del riesgo de enfermedades crónicas no transmisibles como las cardiovasculares y el cáncer.
Gobernanza comunitaria de sistemas de agua potable rural en un contexto altamente privatizado:
Authors: Boso Gaspar Àlex , Millán María Fernanda , Sánchez Galvis Luz Karime
Published: September 2023

El artículo examina la gobernanza comunitaria de sistemas de agua potable rural en La Araucanía, en el sur de Chile. Mediante diversas técnicas de investigación social entre las que se incluyen entrevistas semiestructuradas, observación participante y el análisis de redes sociales, se obtuvieron resultados que señalan el capital social y la patrimonialización del recurso como principales mecanismos generadores de cooperación comunitaria que facilita la subsistencia del sistema. En un contexto de alta privatización, el estudio identifica la enajenación de los derechos del agua y algunas características de grupo, como la carencia de habilidades sociotécnicas, como principales factores que obstaculizan la pervivencia del sistema.
The Right to Universal Accessibility
Authors: De Asís Roig Rafael
Published: September 2023

This paper presents universal accessibility from a human rights perspective. This approach provides a comprehensive view of universal accessibility, which can be considered as a specific right or as part of the essential content of any right. Despite its self-evident justification, this right is not legally recognized.
THE INFLUENCE OF INDIVIDUAL OCCLUSIVE CAPS ON THE BALANCE FUNCTION OF ATHLETICS-ROWERS
Authors:   National University of Ukraine on physical education and sport, Pastuhova Victoria , Zinchenko S. ,   National University of Ukraine on physical education and sport
Published: September 2023

The purpose of this study was to evaluate the sensorimotor coordination of movements of highly qualified rowers against the background of the application of an individual occlusive hard mouth guard. The study of the balance function was carried out with the help of a stabilographic analyzer before the application of the mouth guard, after one month and after 4 months. To assess vestibular stability, classical parameters that have a stable connection with the physiological processes of the statokinetic function were used. During the study, an increase in the balance function quality indicator was observed, which indicates an improvement in the work of the stabilizer muscles of the athletes' body, as well as their proprioceptive sensitivity, which is reflected in a 12 % increase in quality of the equilibrium function in the Romberg test with eyes closed. An increase in the level of development of coordination abilities was noted, in particular, the ability to maintain static and dynamic balance. A decrease in the average speed of the center of pressure movement during the research confirmed the positive dynamics in the functional state of the stabilizer muscles of the athletes' body and the improvement of their coordination abilities. A similar positive trend is observed in the dynamics of other indicators (coefficient of sharp change in the direction of vector movement, spread of the center of pressure in the front-back and transverse directions, the area of the confidence interval of the ellipse). Thus, the use of individual occlusive caps makes it possible to improve the balance indicators of the athlete's body during competitive exercises.
Gebe Kadınların Koronavirüse İlişkin Korkularının Doğum Öncesi Bağlanmaları ile İlişkisi
Authors: BALTACI Nazlı , KOÇ Emine , ODABAŞOĞLU Emel
Published: September 2023

Amaç: Bu çalışma gebelerin COVID-19’a ilişkin korku ve doğum öncesi bağlanma düzeylerini ve bunlar arasındaki ilişkiyi belirlemeyi amaçlamaktadır.

Yöntem: Tanımlayıcı tipte olan araştırma, Türkiye’nin Karadeniz Bölgesi’nde bulunan bir hastanenin Doğum ve Kadın Hastalıkları Poliklinikleri’ne başvuran 210 sağlıklı gebe ile yapılmıştır. Veriler “Gebe Tanılama Formu”, “Covid-19 Korkusu Ölçeği (KKÖ)” ve " Doğum Öncesi Anne Bağlanma Ölçeği (DÖABÖ)" ile toplanmıştır.

Bulgular: Gebelerin KKÖ puan ortalaması 19,39±6,82 ve DÖABÖ puan ortalaması 74,57±8,31 idi. Gebelerin salgın sürecinde gebelik takibi/bakımı için hastaneye gelmeye korkması ve kendisinin/bebeğinin sağlığından endişelenmesi ile KKÖ puanları arasında fark istatistiksel olarak anlamlıydı (sırasıyla p=0,012; p=0,001). Gebelerin gebeliğini planlaması/istemesi ve gebelik izlemi/bakımı için düzenli olarak sağlık kurumuna gelmesi ile DÖABÖ puanları arasındaki fark da istatistiksel olarak anlamlıydı (sırasıyla p=0,032; p=0,003). Gebelerin KKÖ ile bağlanmaya harcanan zaman alt boyutu arasında çok zayıf düzeyde pozitif yönlü anlamlı bir ilişki bulundu (r=0,192, p=0,005).

Sonuç: Araştırmada gebelerin COVID-19’a ilişkin korkuları arttıkça doğum öncesi bağlanmaya harcadığı zamanın arttığı ortaya çıkmıştır.
Selçuk Üniversitesi Tıp Fakültesi Eğitim Yönlendiricilerinin ve Öğrencilerinin Probleme Dayalı Öğrenme Uygulamasına İlişkin Geri Bildirimlerinin Değerlendirilmesi
Authors: MAÇİN Salih , SAMADZADE Rugıyya , AYDOĞAN Senanur
Published: September 2023

Amaç: Probleme Dayalı Öğrenim, bir senaryo temelinde saptanan sağlık sorunlarının çözümlenmesine yönelik çalışma sürecinde önceki bilgilerin kullanılması ve öğrencilerin gereksinim duydukları konuların belirlenmesi, öğrenilmesi ve tartışılması temeline dayanan aktif eğitim yöntemidir. Bu çalışmanın amacı, Probleme Dayalı Öğrenim oturumlarına katılan dönem 1, 2 ve 3 öğrencileri ile eğitim yönlendiricilerinin Probleme Dayalı Öğrenim süreci ile ilgili görüş ve önerilerini değerlendirmektir.

Yöntem: Bu amaçla eğitim yönlendiricilerine 4 Liketten (toplam 20 madde) ve açık uçlu değerlendirmelerden oluşan “Probleme Dayalı Öğrenim Süreci Geri Bildirim Formu”, Tıp fakültesi öğrencilerine ise “Probleme Dayalı Öğrenim Oturumları Öğrenci Geri Bildirim Formu” dağıtılmıştır.

Bulgular: Eğitim yönlendiricileri en yüksek puanı yönlendirici bilgi notu liketinde “Senaryodaki sorulara ilişkin açıklamalar ve/veya hatırlatmalar Probleme Dayalı Öğrenim sürecini yönlendirmede yararlı olmuştur” maddesine (%71,8) vermiştir. En düşük puan ise senaryo liketinde “Öğrenciyi, bilgiyi değişik öğrenme kaynaklarından araştırmaya teşvik etmiştir” maddesi almıştır (%30,8). Geri bildirimler sonucunda öğrenciler, en yüksek puanı eğitim kategorisinde “Yönlendirici etkili geri bildirimler vermekteydi” (%98,2) sorusuna sağlamışlardır. En düşük puan “Senaryo ilgi çekiciydi” (%71,2) sorusuyla senaryo kategorisinde olmuştur.

Sonuç: Çalışma verilerine göre eğitim yönlendiricileri ve öğrencilerden Probleme Dayalı Öğrenimle ilişkili olumlu yönde geri bildirimler alınmıştır. Bu geri bildirimler göz önünde bulundurularak öğrenim hedefleri ile uyumlu senaryolarla Probleme Dayalı Öğrenim oturumlarının geliştirilmesi düşünülmektedir.
Key virtualization technologies and approaches to its integration into the architecture of infrastructure solutions
Authors: Смирнов И.О.
Published: September 2023

В работе проведен анализ существующих технологий виртуализации, подходов к ее интеграции в архитектуру инфраструктурных решений. Выполнено сравнение достоинств и недостатков различных типов виртуализации, в удобном графическом виде перечислены преимущества и недостатки каждого из них, выделены основные факторы различия между виртуализацией, симуляцией и эмуляцией. В статье делается вывод, что разделение одной физической машины на несколько виртуальных машин позволяет максимально эффективно использовать доступные ресурсы вычислительных систем, снизить затраты и повысить эффективность работы.

The article analyzes the existing virtualization technologies, the basic types of virtualization and approaches to its integration into the architecture of infrastructure solutions. The advantages and disadvantages of different types of virtualization are compared and presented in a convenient graphical form, the main differences between virtualization, simulation and emulation are highlighted. The article makes a conclusion that the division of one physical machine into several virtual machines allows the most effective use of available resources of computer systems, reduce costs and increase the efficiency of work.
Evaluation of the efficiency of inflicting damage to a group air target without taking into account the enemy’s counteraction
Authors: Аюш К.Х. , Баланян С.Т. , Белоножкин В.В. , Верницкий Е.В.
Published: September 2023

Определены значения вероятности нанесения ущерба элементам групповой воздушной цели в существующих условиях и с использованием модернизированного метода Т. Саати, учитывающего ранжирование важности элементов данной воздушной цели. Произведен расчет потребного наряда управляемых авиационных ракет класса «воздух – воздух», необходимого для нанесения ущерба групповой воздушной цели. Произведена оценка эффективности использования метода, учитывающего ранжирование важности элементов групповой воздушной цели, где в качестве критерия эффективности использовалось математическое ожидание количества уничтоженных важных элементов групповой воздушной цели.

The article determines the values of the probability of causing damage to the elements of a group air target under existing conditions and using the modernized T. Saaty’s method, which takes into account the ranking of the importance of the elements of a given air target. The authors make a calculation of the required outfit of guided air-to-air missiles necessary for causing damage to a group air target. The article evaluates the efficiency of the applied method, which takes into account the ranking of the importance of elements of a group air target. As an efficiency criterion, there were used a mathematical expectation of the number of destroyed important elements of a group air target.
SQ HDM Sublingual Immunotherapy Tablet for the Treatment of HDM Allergic Rhinitis and Asthma Improves Subjective Sleepiness and Insomnia: An Exploratory Analysis of the Real-life CARIOCA Study
Authors: Jaffuel D , Serrano E , Leroyer C , Chartier A , Demoly P
Published: September 2023

Background: Knowledge of the effectiveness of house dust mite (HDM) sublingual immunotherapy (SLIT) in allergic rhinitis (AR) and asthma-associated sleep disorders remains incomplete. A noninterventional study was conducted to assess the effect of the standardized quality (SQ) HDM SLIT tablet on safety and symptoms in adults with respiratory allergies caused by HDM. The study also assessed the status of insomnia and daytime sleepiness in patients with AR and/or asthma-associated sleep disorders treated with the SQ HDM SLIT tablet. Methods: This was a 12-month multicenter, longitudinal, and prospective study. Participants started the SQ HDM SLIT tablet for moderateto-severe HDM-induced AR that was persistent despite the use of symptom-relieving medication or HDM-induced asthma-associated sleep disorders that were not well controlled with inhaled corticosteroids and were associated with mild-to-severe HDM-induced AR. Sleep symptoms were measured using the Insomnia Severity Index (ISI) questionnaire and the Epworth Sleepiness Scale (ESS). Results: A total of 1526 adult patients were enrolled, and 1483 were eventually included in the analysis. At baseline, 41.5% of patients reported sleep disorders; of these, 77.0% had insomnia and 28.9% experienced excessive daytime sleepiness. Insomnia was significantly more frequent among patients with uncontrolled AR (83.1%) than among those with controlled AR (52.6%) (P<.0001). Over time, 48.3% and 59.7% of patients, respectively, reported an improvement greater than the minimal clinically important difference in the ISI and ESS scales. Conclusion: In patients with HDM-induced AR and/or asthma-associated sleep disorders, an improvement in subjective insomnia and sleepiness was observed after 1 year of treatment with the SQ HDM SLIT tablet in a real-life setting.
Modeling Tri-Model Data With a New Skew Logistic Distribution
Authors: Pathak Dimpal , Hazarika Partha Jyoti , Chakraborty Subrata , Das Jondeep , Hamedani G.  G.
Published: September 2023

This paper considers a new family of the trimodal skew logistic distributions. Some properties of this distribution, including moments, moments generating function, entropy, maximum likelihood estimates of parameters and some other properties, are presented. A simulation study is conducted to examine the performance of the parameters. Numerical optimization is carried out via two real-life datasets. Results show that the new distribution is better ﬁtted in terms of these datasets among logistic, skew logistic and alpha skew logistic distributions based on the value of AIC and BIC.