bluuebunny/crossref_metadata_2025 huggingface dataset:
Clinical characteristics and assessment of risk factors in patients with influenza A-induced severe pneumonia after the prevalence of SARS-CoV-2
Authors: Ma Yujie , Gao Qiang
Published: April 2024

Purpose

The aim of this study is to describe the novel epidemiological and clinical characteristics of influenza A-induced severe pneumonia occurring after the prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and to further assess its potential risk factors for mortality.

Methods

We retrospectively studied the consecutive case series of 30 patients with confirmed influenza A-induced severe pneumonia treated in the intensive care unit at Dazhou Central Hospital in Sichuan, China, from March 1 to April 30, 2023. Logistic regression was used to analyze the independent risk factors, and receiver operating characteristic (ROC) curves were applied to evaluate the predictive efficacy of associated risk factors for mortality.

Results

The mortality rate was 33.3% in this study. Independent risk factors for mortality of patients were acute respiratory distress syndrome (ARDS) (p = 0.044) and septic shock (p = 0.012). ROC statistics for ARDS and septic shock to predict mortality in patients with influenza A-induced severe pneumonia demonstrated an area under the curve of 0.800 (sensitivity 80.0%, specificity 80.0%) and 0.825 (sensitivity 70.0%, specificity 95.0%), respectively.

Conclusion

ARDS and septic shock were the independent risk factors for mortality in patients with influenza A-induced severe pneumonia following the end of the SARS-CoV-2 pandemic. But high level of next generation sequencing reads Aspergillus coinfection, and comorbidities did not increase death risk of the study population.
Extreme Return Spillover Between the WTI, the VIX, and Six Latin American Stock Markets: A Quantile Connectedness Approach
Authors: Kruel Maximiliano , Ceretta Paulo Sergio
Published: April 2024

This study examined extreme return spillovers and connectedness between crude oil (West Texas Intermediate), the Volatility Uncertainty Index (VIX), S&P 500, and six Latin American stock markets, namely, Argentina, Brazil, Chile, Colombia, Mexico, and Peru, using quantile connectedness. This approach allowed for a nuanced investigation of connectedness and added to the understanding the integration between these markets. The results indicated that the S&P 500 market was a full sender of spillover in the whole sample of the quantiles, when, to the contrary, the oil market was the highest receiver. The total spillovers were more intense during extreme quantiles, with swings between transmission and reception for VIX, Colombia, Mexico, and Peru. In addition, when the market turned to operate during bullish conditions, the VIX became a strong sender of spillover. Furthermore, an intense spillover was observed only in the lower and upper quantiles, and the spillover was sharper for the extreme upper quantile.
Bone-artefact production in late Neolithic central China: evidence from Pingliangtai
Authors: Pei Xiaochen , Cao Yanpeng , Yang Yidi , Liew Chun Mun , Zhang Chi , Qin Ling , Deng Zhenhua , Zhu Shuzheng , Chen Yan , Zhao Hao , Ning Chao , Hudson Mark J. , Zhang Ying , Zhang Hai
Published: April 2024

As an important component of prehistoric subsistence, an understanding of bone-working is essential for interpreting the evolution of early complex societies, yet worked bones are rarely systematically collected in China. Here, the authors apply multiple analytical methods to worked bones from the Longshan site of Pingliangtai, in central China, showing that Neolithic bone-working in this area, with cervid as the main raw material, was mature but localised, household-based and self-sufficient. The introduction of cattle in the Late Neolithic precipitated a shift in bone-working traditions but it was only later, in the Bronze Age, that cattle bones were utilised in a specialised fashion and dedicated bone-working industries emerged in urban centres.
Utilization of time-driven activity-based costing and process simulation in cost management of organization
Authors: Halaska Michal , Sperka Roman
Published: April 2024

The deployment of information and communication technologies in organizations is on the rise. Many organizations consider the application of technologies to be a crucial key to improve their processes. However, traditional costing systems are not suitable for cost estimation of business processes due to the use of volume-based cost drivers, which are often not adequate for the structure of today’s organizations. In this research, we present an overview of how the TDABC (time-driven activity-based costing) model can be combined with process mining and business process simulation for cost estimation of such processes. The objective of this paper is to use the cost dimension as a major attribute for the potential implementation of robotic process automation (RPA) in companies. However, information and communication technologies could be considered in general. We demonstrate our approach in a case study that takes advantage of a real-life event log containing transactional data representing the loan application process in an insurance company. The event log is analyzed and processed using process mining techniques. Based on the preprocessing, a simulation model representing the original loan application process is designed. The designed simulation model is then used for simulation of partial and full implementation of RPA through separate scenarios. Then, we add the cost dimension to the simulation by enriching the event log with cost data based on a formalized cost model. We show that even though partial implementation of RPA might not deliver significant increase in efficiency in the process, it might still represent significant cost savings.
Farklı Mikrohibrit Kompozitlerin Renk Stabilitesi ve Translüsensi Parametresi Açısından Karşılaştırılması: in Vitro Çalışma
Authors: Turan Yeşim , Senirkentli Güler Burcu , Sonkaya Ezgi , Ciftci Volkan , Çakmak Eda
Published: April 2024

Amaç: Bu in vitro çalışmada farklı mikrohibrid kompozitlerin distile su veya kahvede bekletildikten sonra renk stabilitelerinin ve translüsensi parametrelerinin (TP) karşılaştırılması amaçlanmıştır.
Gereç ve Yöntem: Üç farklı mikrohibrit kompozit rezin materyalden [G-eanial Anterior (GC, Japonya), Filtek Z250 (3M, ABD), yeni geliştirilen Üniversal Kompozit (Dolgunn-Himg, Türkiye)] her gruptan 20 adet ve toplamda 60 adet disk olacak şekilde örnekler oluşturuldu. Örneklerin yarısı distile suda diğer yarısı hazır kahve içeren kaplarda bekletildi. Renk stabilitesini değerlendirmek için başlangıç, 1. ve 4. hafta sonunda; TP için ise başlangıç ve 4. hafta sonunda bir spektrofotometre ile ölçümler yapıldı. Ortalama L*,a*, b* renk değişim değerleri CIEDE2000 renk formülüne (ΔE00) uygulandı. Renk parametresi için; renk değişim değerleri (ΔE) ve TP için; translüsensi değişim değerleri (ΔTP) hesaplandı. Verilerin analizinde tekrarlı ölçümlerde iki yönlü varyans analizi kullanılmıştır. Küresellik varsayımı Mauchly’nin W testi ile değerlendirilmiştir. Çoklu karşılaştırmalarda LSD testi kullanılmıştır (p<0.05).
Bulgular: Kompozit rezin örneklerde 1 ve 4 hafta kahvede bekletme sonrası anlamlı düzeyde renk değişimi (ΔE: 3.45-7.93) gözlendi. En yüksek renk değişimi Dolgunn kompozit grubunda (p<0.001; p=0,001) saptandı. Kahve ve kontrol grubunda yer alan kompozitlerin TP değerlerinde farklılık gözlenmedi (F=1,821 p=0,181; F=0,191 p=0,828).
Sonuç: Çalışmada, restoratif materyallerin renk stabilitesinde içerik ve kompozisyonu gibi yapısal özelliklerinin renklenmeye neden olan içeriklere maruz kalmaları durumunda önemli bir bileşen olduğu, ancak optik özellikleri belirleyen translüsensi parametresinde anlamlı değişikliğine neden olmadığı gözlenmiştir.
Eksentrik Kayıtlar ile Artikülatör Programlama: Olgu Sunumu
Authors: Türkay Taner , Güven Mehmet Fatih , Demir Necla , Yöndem İsa
Published: April 2024

Protetik tedavide amaç ideal bir protez tasarlayıp üretmektir. İdeal bir protez kişisel olarak estetik, fonksiyon ve fonetik açıdan gereksinimleri karşılamalıdır. Doğru bir teşhis ve tedavi planlaması ise bu süreçte kilit rol oynamaktadır. Dental protezlerin estetik ve fonksiyonları oklüzal düzlemin sagittal ve frontal düzleme göre oryantasyonundan etkilenmektedir. Oklüzal düzlemin transferi için yüz arkı (facebow) yararlı olabilir. Yüz arkı kullanımının yararı sıklıkla sorgulanmış olmasına rağmen, günümüzde hem analog ve hem de dijital iş akışlarında, maksiller modelin yüze oryantasyonunda ve maksillo-mandibuler ilişkinin sağlanmasında gerekliliğini korumaktadır. Dijital iş akışlarında, tomografiden elde edilen 3D görüntü, çene hareketi takip cihazı ve optik yüz tarayıcısı kullanılarak bu ilişkilerin transferini sağlamak mümkündür. Ancak her sistem buna uygun değildir. Uygun olmayan sistemlerde bu transferin analog olarak tam ayarlanabilen bir artikülatörde yapılması ve dijital ortama taşınması gerekir.
Bu olgu sunumunda; tam dişsiz üst çene ve alt çene Kennedy Class I dişsizlik olgusunun tam ayarlanabilen artikülatörün eksentrik kayıtlar ile programlanarak yapılmış tedavisi anlatıldı.
Transferencia del conocimiento, una estrategia para el control de riesgos laborales: Revisión bibliográfica
Authors: Flórez Balvin Dayana , Ramírez Reyes María Ingrid , Losada Guitiérrez Joel
Published: April 2024

El presente artículo se centra en una revisión bibliográfica de la transferencia del conocimiento, resaltando la importancia de preservar el capital intelectual del talento humano, unido al objetivo de proporcionar ambientes de trabajo seguros y saludables para los colaboradores, quienes se consideran los actores fundamentales que activan los procesos administrativos y operativos hacia la construcción continua de saberes y experiencias en el contexto de la organización. A partir de estas referencias bibliográficas se procede a realizar un análisis y discusión sobre las posiciones de los autores, para presentar de manera convincente el valor que agrega la transferencia del conocimiento al control de los riesgos laborales, con resultados sostenibles y de permanencia en el tiempo, lo que contribuirá a la minimización de pérdidas humanas y materiales, y representará un nivel importante de efectividad en los procesos de seguridad y salud en el trabajo.
The Acquisition of Adjective Agreement by Bilingual Children
Authors: Stepšys Jonas
Published: April 2024

While studies on the acquisition of adjective agreement in the Lithuanian language are scarce, some research indicates that children face challenges in understanding morphosyntactic relationships, leading to errors in the use of adjectives and nouns in agreement. Consequently, children may switch less common inflections to more common ones, select declension paradigms based on analogy to other words, and exhibit errors in the grammatical category of gender. The present study investigates adjective agreement in bilingual children. Thirty-five bilingual children residing outside Lithuania completed a task based on a corpus of children’s and child-directed speech. The experimental task aimed to capture the diversity of adjective and noun paradigms. Test choices included, alongside the correct one, a paradigm error (a different paradigm inflection), a number error (a different number in the target paradigm), and a gender error (a different gender in the target paradigm). Results reveal that bilingual children encounter the most difficulty with agreement due to inflectional diversity, involving changes in inflection from unproductive to productive paradigms and copying noun inflections. Agreement errors in gender and number are also associated with paradigm diversity.
Outcomes of ECAP-controlled closed-loop spinal cord stimulation therapy in JAPAN: how to increase patient satisfaction with spinal cord stimulation
Authors: Maeda Hiroyuki , Maeda Mutsuhiro , Maeda Takahiro
Published: April 2024

Objective: Orthopedic surgeons commonly encounter patients with low back pain and leg pain. Despite conservative treatment, which may involve the use of weak opioids or NSAIDs, some patients do not experience improvement and may require increased dosages, contributing to concerns about opioid overuse overseas. Spinal cord stimulation (SCS) therapy, which can be trialed without surgical intervention, offers a potential treatment option. We evaluated Inceptiv (Medtronic), a generator that allows new stimulation settings using evoked compound action potentials (ECAPs)-controlled Closed-Loop technology. Methods: We evaluated six patients (four females, two males) who underwent implantation of the Inceptiv generator for SCS therapy. The average walking time (seconds) during a 2.1-meter walk and pain assessment using the Numerical Rating Scale (NRS) were conducted. Patient satisfaction was assessed using a 5-point scale: very satisfied (5), somewhat satisfied (4), neutral (3), somewhat dissatisfied (2), very dissatisfied. (1). Results: The average walking time improved from 11.8 seconds to 6.6 seconds, and the NRS score decreased from 7.6 to 4.2. Patient satisfaction was high, with four patients being very satisfied (5), one somewhat satisfied (4), and one neutral (3). Discussion: SCS therapy with Closed-Loop technology using the Inceptiv generator offers the potential to adjust electrical stimulation to minimize discomfort in daily activities and provide pain relief. It is considered a new treatment option for patients with common orthopedic conditions such as thoracolumbar compression fractures and lumbar spinal stenosis who suffer from chronic refractory pain in routine clinical practice.
OPTIMIZATION POSSIBILITIES IN BULGARIAN LOCAL TAXATION
Authors: Mutafov E.
Published: April 2024

The main goal of this article is to review and analyze the potential of local taxes in terms of increasing revenue to municipalities in Bulgaria. The analysis of local taxation covers a period of 4 years (2018-2021) and it is focused on two directions: to evaluate the collection level of local taxes and to indicate the degree of importance of local taxes compared to the revenues in the municipal budget. In order to guarantee proper information processing, the following methods are used: analysis and synthesis; grouping, systematization, classification, and structural analysis. Results and conclusions are providing information about the local taxes status and the need for change in the local policies in certain municipalities depending on their size and collection levels. The results will have a local impact on the evaluation of missed opportunities to the local budget's revenue capacity and the possibilities to increase their results.
Antimicrobial resistance patterns and virulence gene profiles of Salmonella enteritidis and Salmonella typhimurium recovered from patients with gastroenteritis in three cities of Iran
Authors: Sharahi Javad Yasbolaghi , Hashemi Ali , Javad Mousavi Seyyed Mohammad , Pournajaf Abazar , Bidhendi Soheila Moradi
Published: April 2024

This study evaluated distribution of virulence factors and antibiotic resistance in clinical isolates of Salmonella enteritidis and Salmonella typhimurium in three cities of Iran. Altogether 48 S. enteritidis and S. typhimurium isolates were collected from patients at certain Iranian hospitals between May 2018 and September 2021. Antimicrobial susceptibility testing was performed by disk diffusion and broth microdilution methods. The presence of antibiotic-resistance genes (blaTEM,blaSHV,blaCTX-M,blaNDM,strA, strB, aadA1, tetA, tetB, floR, sul1, sul2, dfrA), integrons (classe 1 and 2), and virulence-associated genes (invA, stn, sopB, spvC, rck, phoPQ) was investigated by PCR and sequencing. Antimicrobial agents like trimethoprim-sulfamethoxazole and imipenem represent highly efficient agents with 97% susceptibility. S. enteritidis and S. typhimurium exhibited high resistance to ciprofloxacin (n = 20, 71.43%) and ceftazidime (n = 9, 45%), respectively. Overall, 3 (6.25%), 13 (27.08%), and 6 (12.5%) isolates were divided into strong, moderate, and weak biofilm producers, respectively. Moreover, blaCTX-M,blaTEM, blaSHV, sul1, sul2, tetA, tetB, floR, strA, and strB resistant genes were detected in 10 (20.8%), 5 (10.4%), 1 (2.08%), 7 (14.58%), 1 (2.08%), 3 (6.25%), 2 (4.1%), 1 (2.08%), 2 (4.1%), 2 (4.1%), respectively. Furthermore, 7 (14.58%) strains had classe 1 integron. All tested S. enteritidis strains had invA and sopB, and all S. typhimurium strains had invA and phoPQ. However, spvC remained undetected in all isolates. Extensive surveillance and efficient control measures against infection help to stop the upsurge of various antibiotic-resistant isolates.
A new goodness-of-fit test for the inverse Gaussian distribution
Authors: Alızadeh Noughabi Hadi , Shafaei Noughabi Mohammad
Published: April 2024

The Inverse Gaussian (IG) distribution is widely used in practice and therefore an important issue is to develop a powerful goodness-of-fit test (GOF) for this distribution. In this article, we propose and examine a new GOF test for the IG distribution based on a new estimate of Kullback-Leibler (KL) information. The properties of the test statistic are presented. In order to compute the proposed test statistic, parameters of the IG distribution are estimated by maximum likelihood estimators, which are simple explicit estimators. Critical values and the actual sizes of the proposed test are obtained. Through a simulation study, power values of the proposed test are compared with some prominent existing tests. Finally, two illustrative examples are presented and analyzed.
Self-control and self-monitoring behaviour of gifted learners in the mathematical problem-solving process: A case study
Authors: Yazgan-Sağ Gönül , Argün Ziya
Published: April 2024

In the study reported on here we used a qualitative case study design to examine the self-control and self-monitoring behaviour of gifted learners in problem-solving processes. We selected 3 gifted secondary learners using the purposeful sampling method. For the study, each learner completed 10 individual problem-solving sessions. A think-aloud protocol as well as observations and interviews were used in each problem-solving session. The gifted learners displayed various and intertwined self-control and self-monitoring behaviour to read, understand, and solve the problems, and to find and verify the answer. They also displayed this behaviour much more frequently in problems that required using visual drawings and/or had long texts. The gifted learners left or adapted self-control behaviour when the behaviour did not work for solving mathematical problems. They made decisions regarding self-control behaviour by means of the self-monitoring process. The participants presented insistent, quick, flexible, and fluent actions for both self-control and self-monitoring processes. Based on our findings, we propose a portrait of gifted learners’ self-regulative behaviour in the mathematical problem-solving process.
Effects of coagulant bath temperature toward separation performance and antifouling properties of PVDF/CA membranes for filtration of dyes
Authors: Reza Muhammad , Rahmayani Ratu Fazlia Inda , Radiman Cynthia Linaya
Published: April 2024

Phase inversion is used to prepare poly(vinylidene fluoride) (PVDF) microfiltration membranes by combining it with the hydrophilic polymer additive cellulose acetate (CA). For the filtration of methylene blue (MB) and acid yellow 17 (AY17), the effects of coagulant bath temperature (CBT) on the separation performance and antifouling properties are thoroughly investigated. SEM analysis shows that the membrane at higher CBT has a larger pore diameter than at lower CBT, resulting in differences in membrane surface hydrophilicity. It is found that the increase in surface hydrophilicity causes the permeability of PVDF/CA membranes to be higher at higher CBT than at lower CBT. Rejection values above 90% indicate that the membranes are more effective for MB separation at both lower and higher CBT. Otherwise, lower CBT provides better AC rejection than higher CBT. The Flux Recovery Ratio, which is higher at higher CBT, remains in the 75–95% range at lower CBT. As a result, lower CBT is better for membrane fouling resistance than higher CBT. In addition, the fouling observed at lower CBT is similar to the fouling observed at higher CBT, but lower CBT has a higher percentage of reversible fouling than higher CBT. The membranes with more reversible fouling are therefore easier to clean using the backwashing process. As a result, PVDF/CA membranes manufactured at lower CBT have better separation performance and antifouling characteristics than those manufactured at higher CBT.
Effect of carbon black from Ageratina adenophora and various other carbon anode plate additives on the performance of lead acid batteries
Authors: Ravi Subban , Vignesh Baskaran , Meimoorthy Nagarajan , Kumar Bharathamani Dhanus , Sathishkumar Lakshmanan , Mohankumar Nagarajan , Kannapiran Nagarajan
Published: April 2024

The incorporation of carbon materials in batteries serves to enhance its performance by improving conductivity, achieving uniform active material distribution, increasing capacity, mitigating sulfation, extending cycle life, and considering potential environmental benefits. Even though several possible mechanisms were reported, how exactly carbon works is not fully understood. In the present study a new form of carbon black was prepared from Ageratina adenophora (CBAa) and investigated for its impact on the electrical conductivity of the negative active material in 2 V lead acid cell. The performance was compared with other commercially available carbons like Graphite PG-10, Carbon N550, Carbon N330 and Carbon Vulcan. The carbon was characterised by XRD, SEM and grain size analysis. The initial capacity of the cell was consistently higher and remained stable at 4.6 W∙h; in the life cycle analysis, the cells showed 290 cycles. The post-life cycle test analysis showed that only a white layer on multiple plates indicating the onset of sulfation and there is no corrosion. The performance of the CBAa prepared in the present work was found to be better when compared with the commercially available carbons.
CNT thin films based on epoxy mixtures: fabrication, electrical characteristics
Authors: Yumalin Timur , Salikhov Timur , Mahato Biltu , Shiverskii Alexey , Abaimov Sergey , Salikhov Renat
Published: April 2024

The simple scaling of silicon transistors no longer ensures the advantages of high energy efficiency, driving research into nanotechnologies beyond silicon. Specifically, digital circuits based on carbon nanotube (CNT) field-effect transistors promise significant advantages in energy efficiency. However, the inability to perfectly control internal nanoscale defects and the variability of carbon nanotubes hinder the realization of very large-scale integrated systems. In this study, we investigated a novel method for fabricating transistors based on carbon nanotubes (CNTs) using epoxy mixtures, obtained the electrical properties of the transistors, and compared their microstructure and composition via the scanning electron microscopy. The carrier mobility on epoxy-based transistors was 28.87 cm²/V∙s, and the transistor switching frequency was 2.2 MHz. The samples exhibited electrical and physical stability over an extended period of time. The use of carbon nanotubes in epoxy resin as a conducting layer for transistors opens significant prospects in the field of electronics. The CNT-epoxy mixture technology allows for more flexible and rapid fabrication of thin-film transistors compared to classical methods. However, it is not appropriate to speak of a complete replacement; in this study, we present an alternative method for producing thin-film transistors, which may be of interest for specific purposes.
MEMBRANA DE NANOCELULOSE COM FATOR DE CRESCIMENTO DO ENDOTÉLIO VASCULAR (VEGF): FUTURO NA CICATRIZAÇÃO DE QUEIMADURAS PROFUNDAS?
Authors: Carvalho Nerlan Tadeu Gonçalves de , Tabushi Fernando , Malafaia Osvaldo , Possiedi Rafael Dib , Manso Jose Eduardo Ferreira
Published: April 2024

Introdução: Queimaduras são lesões causadas por diversos agentes que promovem a destruição da pele podendo chegar à exposição de tecidos mais profundos. Para melhor uso desta variedade de opções de seu tratamento é importante conhecer-se suas causas, extensão e métodos de tratamento.
Objetivo: Atualizar o uso de membranas de nanocelulose, fator de crescimento do endotélio vascular e outros complementos na cicatrização de queimaduras.
Método: Revisão feita com material e análise  selecionados a partir de pesquisa em plataformas virtuais (SciELO, Google Scholar, Biblioteca Virtual em Saúde, Pubmed e Scopus) por meio dos descritores: “proteínas da membrana bacteriana; fator de crescimento do endotélio vascular; VEGFR; curativos biológicos; curativos” e seus equivalentes em inglês “bacterial outer membrane proteins; vascular endothelial growth fator; dressing; VEGFR; biological dressings” com busca AND ou OR, considerando o título e/ou resumo. Após, foi feita leitura na íntegra dos artigos.
Resultado: Foram incluídos 45 artigos.
Conclusão: Embora sejam necessárias mais pesquisas, estudos já publicados evidenciam que o enriquecimento das membranas de nanocelulose com alguns aditivos como o Fator de Crescimento do Endotélio Vascular VEGF) e incorporação de sensores que possam monitorar as condições das feridas resultará em curativos altamente eficazes. Considerando o avanço tecnológico para produzir membranas de baixo custo, associado à inteligência artificial e os esforços dos pesquisadores, em breve o benefício à saúde pública será evidente.
LncRNA LINC01278 Regulates the Prognosis and Related Mechanisms of Gastric Cancer by Targeting miR-129-5p
Authors: Wang Zhenhua , Liu Liyan , Li Zhengliang , Liu Xiaojing , Wang Jundong , Wang Jiaxi , Jiang Guoxiang , Yu Haizhou
Published: April 2024

Gastric cancer, a prevalent malady within the digestive tract, has a complex pathological mechanism and numerous patients. The regulation of gastric cancer process by long non-coding RNA (lncRNA) presented new prospects for the study of its molecular mechanism and the treatment of patients. The abnormal expressed genes in gastric cancer were screened by GSE193109 dataset. The correlation between LINC01278 and the likelihood of survival in patients suffering from gastric cancer was investigated by Kaplan-Meier survival curve and multivariate Cox analysis. LINC01278 in gastric cancer tissue samples and cells was verified via RT-qPCR. The cell counting kit-8 (CCK-8) and transwell assay were selected to detect the growth activity of gastric cancer cells. The association between LINC01278 and miR-129-5p was validated through luciferase reporter assay and RNA-binding protein immunoprecipitation (RIP) assay. Correlation analysis of clinical features revealed an association between LINC01278 and the prognosis in gastric cancer patients. LINC01278 was actively expressed in gastric cancer, which exerts a tumor-promoting effect. Silencing LINC01278 suppressed the biological function of tumor cells through spongiform miR-129-5p. LINC01278 has the potential to serve as a novel biomarker, offering new avenues of research for the prognosis and treatment of gastric cancer.
Increasing the effectiveness of ‘Power Electronics’ classes using a supplementary web-based virtual laboratory setup to impart CDIO skills
Authors:   Department of Electrical and Electronics Engineering, Thiagarajar College of Engineering, Madurai 625 015, India, D Dr. Kavitha , J Manoj Kumar ,   Department of Electrical and Electronics Engineering, Thiagarajar College of Engineering, Madurai 625 015, India, Mu Suriya ,   Department of Electrical and Electronics Engineering, Thiagarajar College of Engineering, Madurai 625 015, India, D Dr. Anitha ,   Department of Applied Mathematics and Computational Science, Thiagarajar College of Engineering, Madurai 625 015, India
Published: April 2024

Abstract: Power electronics is an engineering field dealing with the control and conversion of electrical energy. Many institutions are using CDIO (Conceive/Design/Implement/Operate) framework for their curricular planning and outcome-based assessment which demands huge self-learning. A virtual laboratory is an online platform allowing users to conduct simulations in a digital environment to improve self-learning. In this work, a virtual laboratory which provides an interactive platform for students to learn and experiment with power electronics circuits and devices, without the need for physical equipment is developed. The laboratory consists of a web-based interface that simulates the behaviour of different power electronics circuits. Learners can select different components and parameters to build and test circuits, and observe the results in real-time. The virtual laboratory also provides access to various measurement tools to analyse the behaviour of the circuits. The virtual laboratory has been designed to provide a user-friendly and intuitive interface, with detailed instructions and feedback to support students' learning. The laboratory has been integrated into a power electronics course. Feedback is collected through surveys from a total of 75 students including open ended questions and Likert responses. The learning of two set of students with and without using virtual lab before doing physical experimentation are assessed using a descriptive test. CDIO components analysis is done with the results of Mini projects developed by the students. The results indicate that the virtual laboratory provides a valuable and engaging learning experience and improves learning. Keywords: Virtual laboratory, Online, Simulation, Experimentation, Power Electronics, Analysis, Education
Effectiveness of Crossword Puzzle as a Revision tool in technical education with Pre-test and post-test Analysis.
Authors:   Lecturer, Department of Automobile Engineering, KESs Rajarambapu Institute of Technology, Rajaramnagar, Shivaji University Kolhapur, Maharashtra, India., Sargar Rajendra S. , Desai Pravin A. ,   Lecturer, Department of Automobile Engineering, KESs Rajarambapu Institute of Technology, Rajaramnagar, Shivaji University Kolhapur, Maharashtra, India.
Published: April 2024

Abstract— The main focus of this paper was to check the effectiveness of the Crossword Puzzle as a revision tool in technical education. This activity was implemented on a total of 70 students with 2nd year and 3rd year diplomas in automobile engineering. Pre-test and post-test analysis models are used to check the effectiveness of the Crossword Puzzle as a revision tool. The majority of students enjoyed this activity and responded to feedback questions in agreed and strongly agreed notes. Pre-test, post-test, and student feedback were conducted using Online Moodle software. Data collected were analyzed using MATLAB. Percentage improvement after every activity was calculated and found that student performance improved for both courses and all 11 units. The range of % improvement is from 10.92% in TMM unit-3 to 92.37% in ATS unit-1. Therefore, the Crossword Puzzle revision tool is recommended to be used in other courses in engineering education. Keywords— Active Learning; Crossword Puzzle; Improvement; Revision; Student Learning,
Project based learning and Proctored online assessment in Lab courses to enhance CDIO Skills – A case study of Microcontroller laboratory course
Authors:   Department of Electrical and Electronics Engineering, Thiagarajar College of Engineering, Madurai 625 015, India, D Dr. Kavitha , D Dr. Anitha ,   Department of Applied Mathematics and Computational Science, Thiagarajar College of Engineering, Madurai 625015, India, P.S Dr. Manoharan ,   Department of Electrical and Electronics Engineering, Thiagarajar College of Engineering, Madurai 625 015, India
Published: April 2024

Abstract: CDIO(Conceive/Design/Implement/Operate) is an educational framework for engineering programs that aims to produce graduates possessing all- rounded set of skills and competencies. The laboratory courses plays important role in inculcating CDIO skills. This proposal explains an attempt conducted in a Microcontroller laboratory course which uses proctored online theoretical assessment and project-based learning in lab course. Thus, a blend of group and individual activities are inserted during the conduct of lab. It is proposed to give one project relating the concepts of the course and to conduct at least two online theoretical assessments, one at the end of first cycle of experiments and second at the end of second cycle experiments. A representative list of project titles is provided to the students. Assessment questions include all the aspects such as background theory of the experiments, conduction of experiments, observation, calculations and inferences. Three research questions are formulated and addressed. It is found from the assessment results that these projects and assessments results in the better understanding of the concepts in the experiments. On the other hand, these assessments helps teachers to analyze the difficulty faced by the students in understanding the theory back ground of the laboratory experiment and plan accordingly. The results are strengthened using statistical tests. Keywords: CDIO, PBL, online assessment, lab courses, Microcontroller
Storytelling with Data as an Active Learning Tool for C++ Programming
Authors:   Mechanical Engineering Department, RIT, Rajaramnagar, Islampur 415414, India., Chavan Pruthviraj C. , Patil Ajinkya K. ,   Mechanical Engineering Department, RIT, Rajaramnagar, Islampur 415414, India., Waghmare Chandan A. ,   Mechanical Engineering Department, RIT, Rajaramnagar, Islampur 415414, India., Patil Sharad D. ,   Mechanical Engineering Department, RIT, Rajaramnagar, Islampur 415414, India., Chate Ganesh R. ,   Mechanical Engineering Department, KLS Gogte Institute of Technology, Belagvi 590008, India.
Published: April 2024

Abstract— This study examines how second-year mechanical engineering students are taught C++ programming using the active learning strategy "Storytelling with Data. Teaching a programming language to mechanical students in their second year was difficult, especially for the direct second-year students who were not familiar with C++ programming. " 50% of students struggled on the post-unit test using previous techniques. The new method required students to write topic-based descriptions that included justifications, programs, charts, and graphics. These were turned into videos using mobile devices, and app.yoodli.ai was used to assess them for linguistic elements such as weaker words, filter words, inclusiveness, voice quality, and grammar. According to analysis, 80% of the students scored between 12 and 17 out of 20 on the quiz. To determine the statistical significance, a paired t-test can be used. The p-value (0.01844) is smaller than the set significance level (0.05). As a result, you can reject the null hypothesis. This shows that there is a statistically significant difference in student performance before and after utilizing the "Storytelling with Data" approach. Feedback emphasized the method's beneficial effects on participation, group cooperation, and conceptual understanding. This study shows how "Storytelling with Data" can improve C++ programming instruction, address issues, and promote interactive learning, which improves academic performance and comprehension. Keywords— Storytelling; Computer programming; Pedagogy; Learning environment, Teaching practices.
Innovative Pedagogical Approaches for Diverse Learning Styles and Student-Centric Learning
Authors:   Vidyavardhaka College o Engineering, Mysuru, Dixit Arun C , B Harshavardhan ,   The National Institute of Engineering, Mysuru, B C Ashok ,   Vidyavardhaka College o Engineering, Mysuru, M A Sriraj ,   Vidyavardhaka College o Engineering, Mysuru, K N Prakasha ,   Vidyavardhaka College o Engineering, Mysuru
Published: April 2024

Abstract— Amidst the aftermath of the COVID-19 pandemic, the landscape of education in India has undergone a profound transformation. Traditional methods of teaching and learning, once the bedrock of our educational system, now find themselves met with skepticism from both students and educational institutions. In response to this paradigm shift, this paper delves into the pressing need for a comprehensive overhaul of pedagogical methodologies within the context of engineering education in India. It emphasizes the pivotal role of education and pedagogy, advocating for a departure from conventional models towards a more learner-centric and adaptable framework, tailored to the nuances of the Indian education landscape. In this context, the paper sheds light on the intrinsic value of understanding diverse learning styles, particularly within the backdrop of a digitally driven era. The profound impact of digital platforms on modern education in India is explored, underscoring their potential to revolutionize and enhance the learning experience for Indian students. The paper further examines unconventional techniques that challenge the norms of education as conventionally understood, recognizing their potential to bridge the gap between students' expectations and institutional methodologies. Within the discourse of this paper, special attention is accorded to three distinctive non-conventional pedagogical approaches: 'Cyberhunt', 'Keyword Concept' and ‘Role Switch Teaching’. These methodologies are scrutinized as quintessential examples of innovative strategies that can foster an intuitive and engaging learning environment within Indian classrooms. 'Cyberhunt' immerses students in experiential learning by assigning them virtual quests that mirror real-world challenges, thereby nurturing critical thinking and problem- solving skills tailored to the Indian context. Similarly, the 'Keyword Concept' approach capitalizes on cognitive associations to enhance memory retention and conceptual understanding, catering to the unique learning styles often found in India. Further, the innovative ‘Role Switch’ teaching methodology, which involves assigning students diverse roles in course delivery, was successfully implemented to further enrich the learning experience in the context of control engineering course. Keywords— Need for Change; Learning Style; Cyber hunt; Keyword Concept
The Digital Generation: An Analysis of the Seminal Impact of Internet Usage on Children
Authors:   Bharati Vidyapeeth’s Institute of Management Studies & Research, Navi Mumbai, University of Mumbai, India, Shukla Dr. Manisha , Waghmode Dr. Manisha ,   Bharati Vidyapeeth’s Institute of Management Studies & Research, Navi Mumbai, University of Mumbai, India, Bhosale Yogini ,   Rajarambapu Institute of Technology, Maharashtra, India
Published: April 2024

Abstract — The increased use of smart devices is causing a movement away from traditional learning methods and towards online learning approaches. Concerns have been expressed concerning the harmful impact of increased internet usage among children on a variety of factors, including health, social activities, outdoor participation, academic performance, and behavior. The purpose of this study is to look into how children's internet use affects their academic achievement, outdoor activities, social interactions, behavior, and health. This study presents a model to show the potential correlations between children's internet usage, academic performance, outdoor activities, social interactions, behavior, and health. The study intends to create links and comprehend the total influence of internet usage on children by analyzing these characteristics. A questionnaire with closed-ended questions was used as a survey strategy to collect data for the study. In and around Navi Mumbai, India, 502 responses were collected from parents of school-aged children aged 6 to 12 years. A random sample method was used in the survey research design, and information was gathered using a pre-structured questionnaire.The information gathered was coded and entered into SPSS 20 for analysis. To analyses the data, descriptive statistics and the Chi Square test were used, and conclusions were drawn based on the results. A significant correlation was discovered between children's internet usage, academic achievement, outdoor activities, social interactions, behavior, and health, according to the research. The study's model successfully establishes probable correlations between these factors, and statistical tests confirm these linkages further. Finally, the growing popularity of online learning methods, fueled by the rising use of smart devices, has sparked concerns regarding the influence of internet consumption on children. This study looks into the consequences of internet use on several elements of children's lives. The study proposed model aids in understanding the connections between internet usage, academic performance, outdoor activities, social interactions, behavior, and health. The statistical study supports the probable correlations between these variables, providing important insights into the implications of children's internet usage in the digital age. Keywords— Internet, Internet Usage, Academic Performance, Outdoor Activities, Social Relationship, Behavior, Health.
Financial Stability Implications of CBDC
Authors: Carapella Francesca , Chang Jin-Wook , Infante Sebastian , Leistra Melissa , Lubis Arazi , Vardoulakis Alexandros P.
Published: April 2024

A Central Bank Digital Currency (CBDC) is a form of digital money that is denominated in the national unit of account, constitutes a direct liability of the central bank, and can be distinguished from other central bank liabilities. We examine the positive and negative implications for financial stability of a CBDC under different design options. We base our analysis on the lessons derived from historical case studies as well as on analytical frameworks useful to characterize the mechanisms through which a CBDC can affect financial stability. We further discuss various policy tools that can be employed to mitigate financial stability risks.
Geographical Ways of Settling Cross-Border Disputes in Central Asia
Authors:   Gulistan State University, Nigmatov A. N.
Published: April 2024

The article discusses geographical ways of settling cross-border disputes in Central Asia and Afghanistan through the phased implementation of 5 interrelated measures. Many years of experience and participation in international regional projects enabled the author to propose consistently implemented geographical measures, providing for the creation of a working group to develop and adopt a concept, roadmap, educational courses, training and retraining programs for relevant personnel, the formation of an interregional "Central Asian Geographical Society". The geographical society can be entrusted with the functions of assessing, monitoring and forecasting interregional problems in the field of nature — society — human activity in certain geosystems. The article also reveals the mechanisms of implementation of geographical methods for the effective settlement of cross-border problems of sustainable development.
Impact of Blasting on the Occurrence of Technogenic-Tectonic Earthquakes in the Southern Ural
Authors:   Orenburg Federal Research Center of the Ural Branch of RAS, Belov V. S. , Nesterenko M. Yu. ,   Orenburg Federal Research Center of the Ural Branch of RAS, Galeeva E. R. ,   Orenburg State University
Published: April 2024

The study identified problems associated with seismic processes occurring on the territory of the Southern Ural. Peculiarities of the structure of the Earth’s crust in the Eastern Orenburg region were briefly analyzed. The seismic activity of the studied area was assessed. The analysis revealed possible causes of seismic events. The influence of man-made impacts on the geodynamic activity of the upper part of the Earth’s crust of the studied territory was described. Based on the research, the most active tectonic structures of the Eastern Orenburg region were identified for further study of geodynamic processes in order to prevent their negative impact.
James White y la organización de la Iglesia Adventista del Séptimo Día
Authors: Torres Kevin E.
Published: April 2024

James fue la persona que estuvo “detrás del desarrollo y forma final del modelo de organización adventista del séptimo día”. Su aporte consistió en lo siguiente: (1) Acabar con los prejuicios en contra de la organización previo a 1860, (2) ser el primero en proponer la organización de la Iglesia, (3) convocar la sesión administrativa de 1860, (4) insistir por la legalidad de la Casa Publicadora e instituciones, (5) recomendar la elección de un nombre adecuado que refleje las características distintivas, (6) establecer la 1ra conferencia y (7) adelantar el congreso de 1863 e insistir en el establecimiento de la Asociación General.
Fernando Stahl, los indígenas y los sucesos de Queñuani
Authors: Rivera Moisés
Published: April 2024

Existía una educación denigrante en el altiplano peruano a inicios del siglo XX, añadido a esto, unas condiciones insalubres, siendo la principal causa de esto, la opresión de un triunvirato nefasto: el clero, el gamonal y la autoridad. Sin embargo, la educación en el altiplano pudo florecer gracias al trabajo pionero de Manuel Z. Camacho y, posteriormente, el matrimonio Stalh. Ellos pudieron abrir escuelas en lugares muy peligrosos como Queñuani, creando un legado educativo imborrable.
John H. Kellogg y el sendero de la disidencia
Authors: Jiménez Esli C.
Published: April 2024

El principal propósito es responder a la siguiente pregunta: ¿cuáles fueron las razones de su desfraternización? El autor estudia: (1) el impacto de sus enseñanzas en la Iglesia Adventista del Séptimo Día (IASD), y (2) los resultados que contrajo su posición. La investigación argumenta que, el concepto bíblico de que el cuerpo del cristiano es el “templo del Espíritu Santo” (1 Corintios 6:19), fue llevado por Kellogg hasta rematar en un tipo de panteísmo que postulaba que Dios residía personalmente en todas las cosas vivientes. Tristemente, debido a su inasistencia a la iglesia, la falta en la devolución de diezmos y ofrendas, y el rechazo al don profético de Ellen White. El 10 de noviembre de 1907 fue desfraternizado de la IASD.
El capítulo olvidado de Daniel
Authors: Heredia Jean P.
Published: April 2024

De las cuatro profecías daniélicas, la última (Dn 10-12) resulta ser menos familiar que sus antecesoras (Dn 2, 7, 8). Más aún, de forma específica, el capítulo 10, cuyo contenido calza como perfecta introducción a Daniel 11, llega a ser menos popular todavía, ya sea entre la variedad de estudios académicos como en la amplia gama de sermones eclesiásticos. El objetivo del presente artículo es considerar cuáles han sido, y son, los factores de su poca popularidad.
Biografía de Poncio Pilato
Authors: Rafael Samuel
Published: April 2024

¿Quién fue Poncio Pilato? Se habla poco de él y de su vida antes y después de ser gobernador. Él es conocido por su intervención en el juicio a Jesús, sin la cual habría sido sólo una nota al pie. En el juicio, influyó mucho el trastorno de personalidad narcisista y antisocial, actuando de forma egoísta y no a favor de Jesús, como se percibe a través de una lectura descuidada de la historia. Intentó, astutamente, contraatacar y finalmente vencer a los representantes judíos. Sin embargo, la balanza no se inclinó a su favor.
The World and the Church
Authors: Ricra Samuel E.
Published: April 2024

Este estudio centra su atención en las diferentes crisis por las que la sociedad atraviesa hoy para proponer la reacción que el cristiano debe tener ante cada diferente catástrofe. Primero, se buscará entender con más profundidad los acontecimientos presentados en Mateo 24 a la luz de la secuencia profética del libro de Daniel, específicamente los capítulos dos, siete y once. Segundo, se intentará mostrar cómo el análisis realizado puede ayudar a que el al creyente se prepare a fin de afrontar los tiempos del fin. Finalmente, se brindará una serie de consejos para la vida práctica del creyente.
Liderazgo transformacional y su conexión con el liderazgo bíblico
Authors: Quispe Ninahuaman Helbert Sixto
Published: April 2024

El propósito del estudio es describir los conceptos básicos del liderazgo transformacional y sus cuatro dimensiones, tal como han sido desarrollas por diferentes autores. Esta descripción es comparada con los conceptos bíblicos del liderazgo y analizar si estas dos propuestas sobre liderazgo son compatibles y hasta qué punto estos se relacionan.