bluuebunny/crossref_metadata_2025 huggingface dataset:
Talasemi Majör Hastalarında MRG ile Kardiyak Demir Yükü Ölçümü, Demir Yükünün Kardiyak Fonksiyonlara Etkisinin Değerlendirilmesi ve Doku Doppleri ile Karşılaştırılması
Authors: Güzelbey Tevfik , Gürses Bengi , Sarsılmaz Aysegül , Karasu Ebru , Özveren Olcay , Aydın Yusuf Sinan
Published: April 2024

Amaç: Talasemi majör (TM) hastalarında, düzenli kan transfüzyonları nedeniyle demir birikimi görülmektedir. TM hastalarında morbidite ve mortalitenin en sık nedeni artan demir birikimine bağlı gelişen kardiyak komplikasyonlardır. Kardiyak demir birikimi manyetik rezonans görüntüleme (MRG) ile doğru bir şekilde ölçülebilmektedir. Ancak 3 Tesla (3T) MRG ile gerçekleştirilmiş yeterince çalışma bulunmamaktadır. Bu çalışmanın amacı, kardiyak demir birikimini 3T MRG cihazında T2* relaksasyon tekniği ile ölçmek ve kardiyak T2* değerleri ile karaciğer T2* değerlerinin, serum ferritin seviyesinin, ekokardiyografi ve kardiyak MRG (KMRG)’de sistolik ve diyastolik fonksiyonları değerlendirmek için ölçülen parametrelerin ilişkisini araştırmaktır.
Yöntem: 21 TM hastasına (13 kadın, 8 erkek; ortalama yaş 29,3±7,6) ve 11 sağlıklı gönüllüye (5 kadın, 6 erkek; ortalama yaş 32,4±5,9) kardiyoloji departmanı tarafından transtorasik ekokardiyografi (TTE) yapıldı. TTE’den sonra bir hafta içerisinde kardiyak ve karaciğer demir yükünü değerlendirmek için 3T MRG cihazında 16 ekolu T2* gradiyent Turbo Field Echo (TFE) sekansı kullanıldı. Kardiyak fonksiyonları değerlendirmek amacı ile 2D-Balanced (steady-state free precession)-TFE sekansı ile kısa aks sine görüntüler alındı.
Bulgular: 21 TM hastasının 6’sında kardiyak T2* değeri 12 msn altında ölçüldü. Kardiyak demir birikimi olan ve olmayan TM hastalarında karaciğer T2* değeri, serum ferritin düzeyi, TTE ve MRG’de sistolik ve diyastolik fonksiyonların değerlendirilmesinde kullanılan parametreler arasında anlamlı fark saptanmadı (p>0,05). Ayrıca kardiyak T2* değeri ile ölçülen diğer tüm parametreler arasında anlamlı korelasyon ilişkisi bulunmadı (p>0,05). Serum ferritin düzeyi ile karaciğer T2* değeri arasında orta düzeyde negatif korelasyon saptandı (r = -0,663). TTE’de sistolik veya diyastolik disfonksiyon lehine bulgu bulunmadı.
Sonuç: Kardiyak demir yükünü öngörmede TTE ve KMRG’de ölçülen parametrelerin, serum ferritin düzeyinin ve karaciğer T2* değerinin yeri bulunmamaktadır. TM hastalarının kardiyak demir birikimi ve birikime yönelik şelasyon tedavisi takibinde kardiyak T2* değeri kullanılmalıdır.
Determination of the Knowledge Level of Surgical Intensive Care Nurses in Medical Device Induced Pressure Injury
Authors: Katran Hamdiye Banu , Er Ayşe , Akbulut Berfin , Yıldırım Emek Can , Küser Kübra Melisa , Yıldırım Marziya , Koyuncuoğlu Filiz
Published: April 2024

Aim: The purpose of this study was to measure the level of knowledge and attitudes of nurses in surgical intensive care units (ICUs) about medical device-induced pressure injury.
Method: The cross-sectional study was conducted with 227 surgical intensive care nurses in Turkey between November 2022 and June 2023. “Nurse Introduction Form” and “Pressure Ulcer Knowledge Level Assessment Tool Scale” were used as data collection tools. Since the scale score averages did not comply with normal distribution, Mann Whitney U and Kruskal Wallis tests were used in the statistical analysis of the data.
Results: It was found that the majority of participants (n=227) were in the age range of 26-33 years (n=115), and 66.1% (n=113) had been working in the ICU for 1-5 years. 51.5% (n=117) of the participants reported having received training in medical device-related pressure injury. In the pressure ulcer knowledge level assessment tool, the mean of the "prevention of pressure ulcers" sub-dimension (mean: 4.74) was found to be the highest, while the total knowledge level score was 14.87±5.6 and it was found that the nurses had a moderate level of knowledge.
Conclusion: The findings of the study indicated that nurses' knowledge of medical device-related pressure injuries was inadequate, but that their knowledge of pressure injury prevention increased with increasing levels of education.
Türkiye’deki Bebek ve Devam Formülleri ile Ek Gıdaların Etiket Bilgilerinin Değerlendirilmesi
Authors: Bayram Hatice Merve , Öztürkcan S. Arda
Published: April 2024

Amaç: Bu çalışmanın amacı piyasada satılan bebek ve devam formülleri ile ek gıdaların etiketlerinde belirtilen besin içeriklerini değerlendirmektir. Ayrıca bebek formülleri ile anne sütü, besin değerleri açısından karşılaştırılmıştır.
Yöntem: Bu çalışma kesitsel bir çalışma olup, İstanbul’da yer alan marketlerde bulunan bebek ve devam formülleri ile ek gıdaların içerik bilgileri çalışmaya dahil edilmiştir.
Bulgular: Çalışmaya toplam 11 farklı markadan 18 çeşit bebek formülü, 10 farklı markadan 17 çeşit devam formülü 1, 11 farklı markadan 25 çeşit devam formülü 2 ve 11 farklı markadan 79 çeşit ek gıda (%48.1’i tahıl bazlı, %51.9’u tahıl bazlı olmayan) dahil edilmiştir. Bebek formüllerinin %11.1’i, laktoz ve %10.0’ı toplam yağa göre; devam formüllerinin ise %48.0’ı kolin, %14.3’ü folik asit ve %4.8’i protein açısından düşük olarak sınıflandırılmıştır. Tahıl bazlı ek gıdaların %100’ü B1 vitamini ve %100’ü sodyum, %97.4’ü yağ, %94.7’si protein ve %73.9’u C vitamini açısından; tahıl bazlı olmayan ek gıdaların ise %100’ü A vitamini ve %80.5’i protein açısından düşük olarak sınıflandırılmıştır. Olgun anne sütünde bebek formüllerine göre enerji, toplam yağ ve B12 vitamini daha yüksek olup istatistiksel olarak anlamlı bir fark saptanmıştır (p<0.05).
Sonuç: Bebek ve devam formülleri ile ek gıdaların besin içeriklerinin tebliğlere göre genelinin uygun olduğu saptanmıştır. Bununla birlikte devam formüllerinin özellikle kolin ve folik asit açısından, ek gıdaların ise protein, B1 vitamini ve A vitamini açısından iyileştirilmesi faydalı olacaktır.
The Radical Left and the Movement in Australia against the First Gulf War, 1990–91: Anti-Imperialism at the End of the Cold War
Authors: Smith Evan
Published: April 2024

The Gulf War in 1990–91 came at the end of the Cold War and at a time when the Left across the globe was reassessing itself as the Soviet Bloc collapsed. In this period of flux, the Australian Radical Left had also experienced a series of debates about its configuration, with several different attempts at unity, as well as reconsiderations about the relationship between the extra-parliamentary Left, the trade unions and the Australian Labor Party. After Saddam Hussein’s Iraq invaded Kuwait in August 1990 and several Western powers, led by the USA and Britain, sought to intervene, Bob Hawke’s Labor government supported the coalition against Iraq. A movement against Western intervention in the Gulf and Australia’s involvement in the coalition was built, including sections of the Labor Left, the trade unions, the peace movement, students and the organisations of the Far Left. Most looked back to the decade-long movement against the Vietnam War for the framework for the anti-war campaign, but the Left, in all its guises, had faded in influence since the 1970s. This article will look at how the movement against the First Gulf War developed between August 1990 and March 1991 and how it reflected a fractured and weakened Left in Australia in the dying days of the Cold War.
LIVABILITY AND FUTURES STUDIES OF WORN-OUT URBAN TEXTURES: SCENARIO ANALYSIS FOR EVALUATING THE LIVABILITY SYSTEM AND ACHIEVING SUSTAINABILITY
Authors: Hashemkhani Zolfani Sarfaraz , Hedayatnezhad Kashi Seyed Mostafa , Antuchevičienė Jurgita
Published: April 2024

Urban worn-out textures, due to their ancient and historically valuable physical structures, exhibit low adaptability to urban developments and advancements. Tehran, as a city with a rich historical background, also boasts considerable worn-out textures. Due to economic, geographical, and political conditions, a large population resides in these textures. In this regard, the present research aims to investigate the livability status of residents, identify key indicators, and design scenarios in the worn-out textures of Tehran city. This paper proposes a new approach to MicMac that promotes driving forces to scenarios. The results indicate that the livability of residents in worn-out textures of Tehran city, particularly in central regions, is in undesirable conditions. Furthermore, the analysis of the MicMac matrix showed that housing prices, residents’ income, investment, and an increase in economic activities, as well as the role of urban management, are driving forces that have a vital impact on the livability of residents in worn-out textures. These driving forces have depicted three scenarios for the livability of worn-out textures in Tehran city until the year 2032.
Planet Hunters TESS. V. A Planetary System Around a Binary Star, Including a Mini-Neptune in the Habitable Zone
Authors: Eisner Nora L. , Grunblatt Samuel K. , Barragán Oscar , Faridani Thea H. , Lintott Chris , Aigrain Suzanne , Johnston Cole , Mason Ian R. , Stassun Keivan G. , Bedell Megan , Boyle Andrew W. , Ciardi David R. , Clark Catherine A. , Hebrard Guillaume , Hogg David W. , Howell Steve B. , Klein Baptiste , Llama Joe , Winn Joshua N. , Zhao Lily L. , Murphy Joseph M. Akana , Beard Corey , Brinkman Casey L. , Chontos Ashley , Cortes-Zuleta Pia , Delfosse Xavier , Giacalone Steven , Gilbert Emily A. , Heidari Neda , Holcomb Rae , Jenkins Jon M. , Kiefer Flavien , Lubin Jack , Martioli Eder , Polanski Alex S. , Saunders Nicholas , Seager Sara , Shporer Avi , Tyler Dakotah , Van Zandt Judah , Alhassan Safaa , Amratlal Daval J. , Antonel Lais I. , Bentzen Simon L. S. , Bosch Milton K. D , Bundy David , Chitsiga Itayi , Delaunay Jérôme F. , Doisy Xavier , Ferstenou Richard , Fynø Mark , Geary James M. , Haynaly Gerry , Hermes Pete , Huten Marc , Lee Sam , Metcalfe Paul , Pennell Garry J. , Puszkarska Joanna , Schäfer Thomas , Stiller Lisa , Tanner Christopher , Tarr Allan , Wilkinson Andrew
Published: April 2024

We report on the discovery and validation of a transiting long-period mini-Neptune orbiting a bright (V = 9.0 mag) G dwarf (TOI 4633; R = 1.05 R
⊙, M = 1.10 M
⊙). The planet was identified in data from the Transiting Exoplanet Survey Satellite by citizen scientists taking part in the Planet Hunters TESS project. Modelling of the transit events yields an orbital period of 271.9445 ± 0.0040 days and radius of 3.2 ± 0.20 R
⊕. The Earth-like orbital period and an incident flux of

1.56

−
0.16

+
0.20

F
⊕ places it in the optimistic habitable zone around the star. Doppler spectroscopy of the system allowed us to place an upper mass limit on the transiting planet and revealed a non-transiting planet candidate in the system with a period of 34.15 ± 0.15 days. Furthermore, the combination of archival data dating back to 1905 with new high angular resolution imaging revealed a stellar companion orbiting the primary star with an orbital period of around 230 yr and an eccentricity of about 0.9. The long period of the transiting planet, combined with the high eccentricity and close approach of the companion star makes this a valuable system for testing the formation and stability of planets in binary systems.
The Atacama Cosmology Telescope: Mitigating the Impact of Extragalactic Foregrounds for the DR6 Cosmic Microwave Background Lensing Analysis
Authors: MacCrann Niall , Sherwin Blake D. , Qu Frank J. , Namikawa Toshiya , Madhavacheril Mathew S. , Abril-Cabezas Irene , An Rui , Austermann Jason E. , Battaglia Nicholas , Battistelli Elia S. , Beall James A. , Bolliet Boris , Bond J. Richard , Cai Hongbo , Calabrese Erminia , Coulton William R. , Darwish Omar , Duff Shannon M. , Duivenvoorden Adriaan J. , Dunkley Jo , Farren Gerrit S. , Ferraro Simone , Golec Joseph E. , Guan Yilun , Han Dongwon , Hervías-Caimapo Carlos , Hill J. Colin , Hilton Matt , Hložek Renée , Hubmayr Johannes , Kim Joshua , Li Zack , Kosowsky Arthur , Louis Thibaut , McMahon Jeff , A. Marques Gabriela , Moodley Kavilan , Naess Sigurd , Niemack Michael D. , Page Lyman , Partridge Bruce , Schaan Emmanuel , Sehgal Neelima , Sifón Cristóbal , Wollack Edward J. , Salatino Maria , Ullom Joel N. , Van Lanen Jeff , Van Engelen Alexander , Wenzl Lukas
Published: April 2024

We investigate the impact and mitigation of extragalactic foregrounds for the cosmic microwave background (CMB) lensing power spectrum analysis of Atacama Cosmology Telescope (ACT) data release 6 (DR6) data. Two independent microwave sky simulations are used to test a range of mitigation strategies. We demonstrate that finding and then subtracting point sources, finding and then subtracting models of clusters, and using a profile bias-hardened lensing estimator together reduce the fractional biases to well below statistical uncertainties, with the inferred lensing amplitude, A
lens, biased by less than 0.2σ. We also show that another method where a model for the cosmic infrared background (CIB) contribution is deprojected and high-frequency data from Planck is included has similar performance. Other frequency-cleaned options do not perform as well, either incurring a large noise cost or resulting in biased recovery of the lensing spectrum. In addition to these simulation-based tests, we also present null tests on the ACT DR6 data for sensitivity of our lensing spectrum estimation to differences in foreground levels between the two ACT frequencies used, while nulling the CMB lensing signal. These tests pass whether the nulling is performed at the map or bandpower level. The CIB-deprojected measurement performed on the DR6 data is consistent with our baseline measurement, implying that contamination from the CIB is unlikely to significantly bias the DR6 lensing spectrum. This collection of tests gives confidence that the ACT DR6 lensing measurements and cosmological constraints presented in companion papers to this work are robust to extragalactic foregrounds.
Gas-dynamical Mass Measurements of the Supermassive Black Holes in the Early-type Galaxies NGC 4786 and NGC 5193 from ALMA and HST Observations*
Authors: Kabasares Kyle M. , Cohn Jonathan H. , Barth Aaron J. , Boizelle Benjamin D. , Davidson Jared R. , Sy Janelle M. , Flores-Velázquez Jeysen , Delgado Andrade Silvana C. , Buote David A. , Walsh Jonelle L. , Baker Andrew J. , Darling Jeremy , Ho Luis C.
Published: April 2024

We present molecular gas-dynamical mass measurements of the central black holes in the giant elliptical galaxies NGC 4786 and NGC 5193, based on CO (2−1) observations from the Atacama Large Millimeter/submillimeter Array (ALMA) and Hubble Space Telescope near-infrared imaging. The central region in each galaxy contains a circumnuclear disk that exhibits orderly rotation with projected line-of-sight velocities of ∼270 km s−1. We build gas-dynamical models for the rotating disk in each galaxy and fit them directly to the ALMA data cubes. At 0.″31 resolution, the ALMA observations do not fully resolve the black hole sphere of influence (SOI), and neither galaxy exhibits a central rise in rotation speed, indicating that emission from deep within the SOI is not detected. As a result, our models do not tightly constrain the central black hole mass in either galaxy, but they prefer the presence of a central massive object in both galaxies. We measure the black hole mass to be

(

M

BH

/

10

8

M

⊙

)
=
5.0
±
0.2

[
1
σ

statistical
]

−
1.3

+
1.4

[
systematic
]

in NGC 4786 and

(

M

BH

/

10

8

M

⊙

)
=
1.4
±
0.03

[
1
σ

statistical

]

−
0.1

+
1.5

[
systematic
]

in NGC 5193. The largest component of each measurement’s error budget is from the systematic uncertainty associated with the extinction correction in the host galaxy models. This underscores the importance of assessing the impact of dust attenuation on the inferred M
BH.
Dissipative Dark Matter on FIRE. II. Observational Signatures and Constraints from Local Dwarf Galaxies
Authors: Shen Xuejian , Hopkins Philip F. , Necib Lina , Jiang Fangzhou , Boylan-Kolchin Michael , Wetzel Andrew
Published: April 2024

We analyze the first cosmological baryonic zoom-in simulations of galaxies in dissipative self-interacting dark matter (dSIDM). The simulations utilize the FIRE-2 galaxy formation physics with the inclusion of dissipative dark matter self-interactions modeled as a constant fractional energy dissipation (f
diss = 0.75). In this paper, we examine the properties of dwarf galaxies with M
* ∼ 105–109
M
⊙ in both isolation and within Milky Way–mass hosts. For isolated dwarfs, we find more compact galaxy sizes and promotion of disk formation in dSIDM with (σ/m) ≤ 1 cm2 g−1. On the contrary, models with (σ/m) = 10 cm2 g−1 produce puffier stellar distributions that are in tension with the observed size–mass relation. In addition, owing to the steeper central density profiles, the subkiloparsec circular velocities of isolated dwarfs when (σ/m) ≥ 0.1 cm2 g−1 are enhanced by about a factor of 2, which are still consistent with the kinematic measurements of Local Group dwarfs but in tension with the H i rotation curves of more massive field dwarfs. Meanwhile, for satellites of Milky Way–mass hosts, the median circular velocity profiles are marginally affected by dSIDM physics, but dSIDM may help promote the structural diversity of dwarf satellites. The number of satellites is slightly enhanced in dSIDM, but the differences are small compared with the large host-to-host variations. In conclusion, the dSIDM models with (σ/m) ≳ 0.1 cm2 g−1, f
diss = 0.75 are in tension in massive dwarfs (M
halo ∼ 1011
M
⊙) due to circular velocity constraints. However, models with lower effective cross sections (at this halo mass/velocity scale) are still viable and can produce nontrivial observable signatures.
Spatial Variations and Breaks in the Optical–Near-infrared Spectra of the Pulsar and Pulsar Wind Nebula in Supernova Remnant 0540–69.3
Authors: Tenhu L. , Larsson J. , Sollerman J. , Lundqvist P. , Spyromilio J. , Lyman J. D. , Olofsson G.
Published: April 2024

The supernova remnant (SNR) 0540–69.3, twin of the Crab Nebula, offers an excellent opportunity to study the continuum emission from a young pulsar and pulsar wind nebula (PWN). We present observations taken with the Very Large Telescope instruments MUSE and X-shooter in the wavelength range 3000–25000 Å, which allow us to study spatial variations of the optical spectra, along with the first near-infrared (NIR) spectrum of the source. We model the optical spectra with a power law (PL) F

ν
∝ ν
−α
and find clear spatial variations (including a torus–jet structure) in the spectral index across the PWN. Generally, we find spectral hardening toward the outer parts, from α ∼ 1.1 to ∼0.1, which may indicate particle reacceleration by the PWN shock at the inner edge of the ejecta or alternatively time variability of the pulsar wind. The optical–NIR spectrum of the PWN is best described by a broken PL, confirming that several breaks are needed to model the full spectral energy distribution of the PWN, and suggesting the presence of more than one particle population. Finally, subtracting the PWN contribution from the pulsar spectrum we find that the spectrum is best described with a broken-PL model with a flat and a positive spectral index, in contrast to the Crab pulsar that has a negative spectral index and no break in the optical. This might imply that pulsar differences propagate to the PWN spectra.
Spectroscopic Observations of the Solar Corona during the 2017 August 21 Total Solar Eclipse: Comparison of Spectral Line Widths and Doppler Shifts between Open and Closed Magnetic Structures
Authors: Zhu 朱 Yingjie 英杰 , Habbal Shadia R. , Ding Adalbert , Yamashiro Bryan , Landi Enrico , Boe Benjamin , Constantinou Sage , Nassir Michael
Published: April 2024

The spectroscopic observations presented here were acquired during the 2017 August 21 total solar eclipse (TSE) with a three-channel partially multiplexed imaging spectrometer operating at extremely high orders (>50). The 4 R
⊙ extent of the slit in the north–south direction scanned the corona starting from the central meridian out to approximately 1.0 R
⊙ off the east limb throughout totality. The line widths and Doppler shifts of the Fe x (637.4 nm) and Fe xiv (530.3 nm) emission lines, characteristic of 1.1 × 106 K and 1.8 × 106 K electron temperatures, respectively, varied across the different coronal structures intercepted by the slit. Fe xiv was the dominant emission in the closed fields of an active region and the base of a streamer, with relatively constant 20–30 km s−1 line widths independent of the height. In contrast, Fe x emission exhibited broader (>40 km s−1) line widths in open fields, which increased with height, in particular in the polar coronal hole. Inferences of line widths and Doppler shifts were consistent with extreme ultraviolet (EUV) observations from the Hinode/EUV Imaging Spectrograph, as well as with the near-infrared Fe xiii 1074 nm line observed by Coronal Multichannel Polarimeter. The differences in the spectral line widths between distinct coronal structures are interpreted as an indication of the predominance of wave heating in open structures versus localized heating in closed structures. This study underscores the unparalleled advantages and the enormous potential of TSE spectroscopy in measuring line widths simultaneously in open and closed fields at high altitudes, with minimal exposure times, stray light levels, and instrumental widths.
Analysis of BMR Tilt from AutoTAB Catalog: Hinting toward the Thin Flux Tube Model?
Authors: Sreedevi Anu , Jha Bibhuti Kumar , Karak Bidya Binay , Banerjee Dipankar
Published: April 2024

One of the intriguing mechanisms of the Sun is the formation of bipolar magnetic regions (BMRs) in the solar convection zone (CZ), which are observed as regions of concentrated magnetic fields of opposite polarity on the photosphere. These BMRs are tilted with respect to the equatorial line, which statistically increases with latitude. The thin flux tube model, employing the rise of magnetically buoyant flux loops and their twist by Coriolis force, is a popular paradigm for explaining the formation of tilted BMRs. In this study, we assess the validity of the thin flux tube model by analyzing the tracked BMR data obtained through the Automatic Tracking Algorithm for BMRs. Our observations reveal that the tracked BMRs exhibit the expected collective behaviors. We find that the polarity separation of BMRs increases over their normalized lifetime, supporting the assumption of a rising flux tube from the CZ. Moreover, we observe an increasing trend of the tilt with the flux of the BMR, suggesting that rising flux tubes associated with lower flux regions are primarily influenced by drag force and Coriolis force, while in higher flux regions, magnetic buoyancy dominates. Furthermore, we observe Joy’s law dependence for emerging BMRs from their first detection, indicating that at least a portion of the tilt observed in BMRs can be attributed to the Coriolis force. Notably, lower flux regions exhibit a higher amount of fluctuations associated with their tilt measurement compared to stronger flux regions, suggesting that lower flux regions are more susceptible to turbulent convection.
A Narrow Uniform Core with a Wide Structured Wing: Modeling the TeV and Multiwavelength Afterglows of GRB 221009A
Authors: Zheng Jian-He , Wang Xiang-Yu , Liu Ruo-Yu , Zhang Bing
Published: April 2024

The TeV afterglow of the BOAT GRB 221009A was interpreted as arising from a narrow jet, while the radio-to-X-ray afterglows were interpreted as arising from a wide structured jet. However, there is no model explaining the TeV and lower-energy multiwavelength afterglows simultaneously. We here investigate a two-component jet model, including a narrow uniform core with a wide structured wing, to explain both the multiwavelength afterglows that last up to 100 days. We find that to explain the early TeV afterglow with the inverse-Compton process, we need a circumburst density higher than ≳0.1 cm−3, while the radio afterglow and the H.E.S.S. upper limit combine to constrain the density to be lower at larger radii. Thus, a decreasing density profile with radius is favored. Considering that the rising TeV light curve during the afterglow onset favors a constant-density medium, we invoke a stratified density profile, including a constant-density profile at small radii and a wind density profile at large radii. We find that the two-component jet model with such a stratified density profile can explain the TeV, X-ray, and optical afterglows of GRB 221009A, although the radio fluxes exceed the observed ones by a factor of 2 at later epochs. The discrepancy in the radio afterglow could be resolved by invoking some nonstandard assumption about the microphysics of afterglow shocks. The total kinetic energy of the two components in our model is ≲1052 erg, significantly smaller than that in the single structured jet models.
Determining Cosmological-model-independent H
0 with Gravitationally Lensed Supernova Refsdal
Authors: Li Xiaolei , Liao Kai
Published: April 2024

The reappearance of supernova Refsdal with detailed modeling of the lens cluster allows us to measure the time-delay distance, which serves as a powerful tool to determine the Hubble constant (H
0). We give a cosmological-model-independent method to estimate H
0 through Gaussian process regression, using time-delay measurements from this lensed supernova in combination with supernova data from the Pantheon+ sample. Using eight mass models for the lens cluster, we infer

H

0

=

64.2

−
4.3

+
4.4

km

s

−
1

Mpc

−
1

, and using two cluster models most consistent with the observations, we infer

H

0

=

66.3

−
3.6

+
3.8

km

s

−
1

Mpc

−
1

. Our estimates of the value of H
0 are in 1σ agreement with the results assuming a flat ΛCDM model and the uncertainties are comparable. Our constraint results on H
0 from the eight lens models and the two lens models indicate 2σ and 1.8σ tensions with that estimated by Supernova H0 for the Equation of State, respectively. However, our median values of H
0 from the two sets of lens models show good consistency with H
0 inferred from Planck cosmic microwave background observations assuming a ΛCDM model within 1σ. We also find that our results for H
0 indicate 2σ deviations and 1.7σ deviations from the constraint results of H
0 using six time-delay quasars by H0LiCOW with the same analysis method.
Repair of type II paraesophageal hernia with Nissen fundoplication in a patient with von Willebrand disease and spondylolisthesis – a clinical case report
Authors: Fibiger Grzegorz , Glądys Kinga , Fibiger Wojciech , Pasternak Artur , Szura Mirosław
Published: April 2024

Hiatal hernias continue to be fairly common in clinical practice. However, the variety of different symptoms presented by patients may hinder establishing the ultimate diagnosis. Nevertheless, currently, the diagnosis of hiatal hernia can be easily established, based on barium swallow radiography. We would like to present a clinical case report of a patient with complex medical history, including von Willebrand disease, degenerative spinal disease, and chronic sinusitis, who was finally diagnosed with hiatal hernia and treated with a standard laparoscopic Nissen fundoplication. Our case focuses on the significance of comorbidities on patients’ symptoms, which sometimes may mislead the therapeutic process.
A rare clinical case of extra-gastrointestinal stromal pancreatic tumor
Authors: Shabunin Alexey , Bagatelia Zurab , Tavobilov Mikhail , Dolidze David , Andreytsev Igor , Sheviakova Tatiana , Ivanova Nataliya , Foshina Anna , Chibukhchyan Zarui , Covantsev Serghei
Published: April 2024

Extra-gastrointestinal stromal tumors arising from the pancreas are extremely rare. To date, just over 30 cases have been described in the world literature. A clinical observation of a 67-year-old patient with dull epigastric pain and a large cystic solid neoplasm instrumentally identified as an extra-gastrointestinal stromal tumor of the head of the pancreas is presented. The volume of surgical intervention consisted of pancreatogastroduodenectomy and right-sided hemicolectomy, since tumor invasion into the transverse mesocolon was detected intraoperatively. The final diagnosis of extra-gastrointestinal stromal sarcoma of the head of the pancreas with invasion into the mesocolon pT4N0M0, stage IIIb was made on the basis of histopathology and immunohistochemistry results.

Extra-gastrointestinal stromal pancreatic tumors require careful differential diagnosis with other large abdominal masses. Timely diagnosis and use of modern treatment algorithms make it possible to avoid further disease progression.
Complications due to ultrasound transthoracic cutting biopsy of peripheral pulmonary lesions and lesions in the chest wall and mediastinum
Authors: Argirov Dimcho , Yavorov Boyko , Aleksiev Vladimir , Chapkunov Anastas , Shterev Filip , Kartev Stanislav , Uchikov Petar , Vazhev Zaprin
Published: April 2024

Introduction: Evaluation of patients with peripheral lung lesions and lesions of the chest wall and mediastinum is challenging. The nature of the lesion identified by imaging studies can be determined by histological evaluation of biopsies. An important place in this direction is the ever-increasing popularity among thoracic surgeons of the transthoracic biopsy with a cutting needle under ultrasound control (US-TTCNB).

Aim: This article aims to outline potential complications that may arise from transthoracic incisional biopsy performed under ultrasound guidance, along with a percentage reduction algorithm and treatment approaches.

Materials and methods: The present study is based on 264 patients with CT-detected peripheral lesions of the lung, chest wall, and the mediastinum performed in the Department of Thoracic Surgery of Kaspela University Hospital in Plovdiv over a period of 2 years (January 2020 – December 2021).

Results: Complications were found in 11 (4.17%) patients.

Conclusion: Our established biopsy technique achieves a sufficient amount of biopsy material with a low rate of post-biopsy complications.
Prognostic models of drug-induced neutralizing antibody formation in patients with rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis treated with TNF-α blockersockers
Authors: Kraev Krasimir , Hristov Bozhidar , Uchikov Petar , Kraeva Mariya , Geneva-Popova Mariela , Popova Stanislava , Basheva-Kraeva Yordanka , Stoyanova Nina S. , Mitkova-Hristova Vesela
Published: April 2024

Aim: This study aimed to construct prognostic mathematical models utilizing multifactorial regression analysis to assess the risk of developing drug-induced neutralizing antibodies in patients with rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis treated with tumor necrosis factor alpha blockers.

Materials and methods: ﻿Over a four-year period, we enrolled 213 patients in this study and divided them into three groups: the rheumatoid arthritis group (n=121), the ankylosing spondylitis group (n=50), and the psoriatic arthritis group (n=42). The study included also a group of healthy controls consisting of 31 healthy subjects who matched the patient groups in age, sex, body mass index, and conditions typical for rheumatology patients. Prognostic mathematical models based on statistically significant factors determined through univariate correlation and regression analyses incorporated patient medical history and serological and immunological data.

Results: The study encompassed all 213 patients and 31 healthy controls. Data analysis was conducted at 12 and 24 months after commencing treatment. During this follow-up, the patients exhibited the highest percentage of antidrug antibodies. At 6 months, 6.57% of patients had confirmed neutralizing antibodies, which increased to 12.69% at 12 months and 17.72% at 24 months. Multivariate logistic regression analysis revealed that factors such as age over 55 years, excess weight, smoking, and absence of methotrexate treatment at a dose less than 7.5 mg per week had the highest predictive value.

Conclusions: Investigating clinical and biological markers with predictive value for individual patients’ therapeutic responses is a complex task. This complexity arises from the interplay of at least three distinct parameters: the patient’s disease state, drug bioavailability, and pathophysiological changes within the patient’s body, all of which are influenced by various factors.
La patrie et la guerre
Authors: Chanet Jean-François
Published: April 2024

Jean-Jacques Becker a été un lecteur et un commentateur inépuisable de L’Armée nouvelle de Jean Jaurès, depuis ses travaux consacrés à l’opinion publique française au début de la Première Guerre mondiale. L’exposé des motifs de la loi, devenu ouvrage théorique, permettait à Jean-Jacques Becker de présenter la pensée de Jaurès sur l’organisation de la défense en cas de guerre. Mais cette contribution montre aussi que ses recherches l’ont constamment amené à contextualiser l’œuvre jaurésienne, dans un spectre d’opinions d’une grande diversité. Cette connaissance intime de l’œuvre rend plus précieuse encore l’édition que Jean-Jacques Becker a préparée pour l’édition du 13 e volume des Œuvres publiées aux éditions Fayard en 2012.
Jean-Jacques Becker : pour une histoire culturelle et politique des gauches
Authors: Jousse Emmanuel
Published: April 2024

Historien des gauches, Jean-Jacques Becker l’a été dans le prolongement d’un engagement politique aux côtés des communistes, dans le contexte de la Deuxième Guerre mondiale et de la Résistance. Le lien entre l’expérience du témoin et le regard de l’historien a été essentiel pour poser des problèmes historiques sur le militantisme, l’organisation, et les cultures politiques. Dans le prolongement d’une histoire politique en renouvellement depuis les années 1980, Jean-Jacques Becker s’est attaché, jusqu’à la publication de l’ Histoire des gauches en France , à écrire cette histoire des gauches sous le signe d’une histoire culturelle du politique.
Jean-Jacques Becker, directeur de recherches
Authors: Thénault Sylvie , Jousse Emmanuel
Published: April 2024

Jean-Jacques Becker, tout au long de son parcours intellectuel, a été un passeur, à la fois enseignant et directeur de recherches. Cet entretien revient sur ce rôle essentiel, quoique rendu invisible par le constant refus de Jean-Jacques Becker de s’instituer comme le maître à penser d’une génération.
Les soins palliatifs à la lumière de la théorie du caring
Authors: Saouma Nehmé Mona
Published: April 2024

Les valeurs humanistes des soins et l’approche relationnelle au cœur du caring concordent avec les valeurs véhiculées en soins palliatifs. Cette étude propose de comprendre la pratique du caring en soins palliatifs auprès de patients en fin de vie. Le cadre repose sur la Théorie du Human Caring de Watson (1979). Une étude qualitative a été réalisée. Les données ont été collectées auprès de l’infirmière spécialisée, l’infirmière-chef et les infirmières en oncologie (n = 9), par des entrevues individuelles, l’observation directe non participante et le journal de bord. L’analyse des données a permis de mettre en lumière une réalité substantielle de la pratique infirmière du caring en soins palliatifs à travers la compassion, la présence, le respect et l’écoute active, tout en plaçant la personne au cœur du soin. Ainsi, l’approche de caring est considérée comme une solution intéressante pour une pratique professionnelle optimale en soins palliatifs.
Entre soin et théâtre, l’art en partage : la création « Paroles et parole »
Authors: Métrailler Al-Sayeg Jocelyne
Published: April 2024

« Paroles et parole » est une petite forme théâtrale itinérante, réalisée à la suite de la rencontre d’Olivia Seigne, comédienne et metteure en scène et Jocelyne Métrailler al-Sayegh, infirmière spécialisée en soins palliatifs. Cette création souhaite offrir un espace de rencontres entre patient·e·s et professionnel·le·s pour permettre une meilleure connaissance et compréhension mutuelle et peut-être même permettre, de part et d’autre, des prises de conscience. Cette pièce interroge la place du langage dans le soin et met en évidence l’importance de l’écoute, de l’attitude corporelle et du choix des mots dans la construction de la relation thérapeutique.
Le potentiel du design thinking pour les politiques publiques : Développer les capacités créatives pour co-construire la ville inclusive avec les personnes âgées
Authors: Castro-Gonçalves Luciana , Josion-Portail Margaret , Zadra-Veil Cathy
Published: April 2024

L’adaptation des villes au vieillissement constitue un défi majeur pour les politiques publiques bottom-up . Dans ce cadre, cette recherche s’intéresse aux adaptations des méthodes de design thinking (DT) pour permettre la participation des citoyens âgés aux dispositifs de co-construction des innovations urbaines. L’analyse de trois ateliers de créativité montre comment les facteurs liés à la préparation des ateliers (appui sur des acteurs tiers, adoption d’une configuration intergénérationnelle, sensibilisation des participants âgés quant au rôle qu’ils peuvent jouer dans la génération de solutions) et à l’atteinte des finalités du processus créatif participent au développement des capacités créatives des personnes âgées. Les résultats sont discutés sous l’angle des apports à la littérature sur le DT et sur la participation des publics vulnérables au processus créatif. Codes JEL : R580, H750, O360, O350
Une Amérique en « guerre incivile »
Authors: Mélandri Pierre
Published: April 2024

Dans les années 1950, les différences entre républicains et démocrates semblaient se résumer à celles entre « bonnet blanc et blanc bonnet ». Aujourd’hui, elles les entraînent dans une « guerre incivile » sur presque tous les sujets. Le « grand chambardement » des sixties et les retombées de la mondialisation néolibérale se sont conjugués avec l’évolution du système électoral et du paysage médiatique pour creuser un fossé entre les deux grands partis politiques. Un fossé que l’élection de Donald Trump en 2016 n’a fait qu’approfondir et que, jusqu’à présent, Joe Biden n’a pas réussi à vraiment réduire .
Les États-Unis, fer de lance de l’économie mondiale
Authors: Bensaidani Anis , Baudchon Hélène
Published: April 2024

Globalement, l’économie américaine se porte bien : la croissance perdure malgré le choc inflationniste et le resserrement monétaire massif engagé pour le juguler. Le taux de chômage se situe à un niveau historiquement bas. Grace à l’hégémonie du dollar et à leur leadership dans les nouvelles technologies, les États-Unis restent le fer de lance de l’économie mondiale. Certains points faibles persistent toutefois, au premier rang desquels figurent les déséquilibres extérieurs et budgétaires et les inégalités socio-spatiales. La recherche d’un renouveau industriel s’accompagne d’un retour au protectionnisme, tandis que l’essor du secteur pétrolier contrecarre les mesures en faveur de la décarbonation .
La grande stratégie américaine vers l’Asie et l’Indo-Pacifique : un bilan contrasté
Authors: Burdy Jean-Paul
Published: April 2024

En 2011, le président Obama annonce un « pivot stratégique vers l’Asie » afin de maintenir le leadership de la puissance américaine dans une région au poids économique croissant, et face à une Chine qui devient un rival systémique. Du « pivot asiatique », les États-Unis passent ensuite au « rééquilibrage stratégique » en Indo-Pacifique. Au terme des présidences Obama, Trump et Biden, et à la veille d’une présidentielle américaine décisive, le 5 novembre 2024, le bilan de cette grande stratégie apparaît pour le moins contrasté .
Development of a Collaborative Online International Learning (COIL) Activity
Authors: Young Judith A. , Draucker Claire Burke , Fairley-Murdoch Marianne , Lillie Matthew
Published: April 2024

Global mobility has made global health a priority within nursing curricula and health care organizations. A collaborative online learning activity could promote international perspectives of health care delivery. Including a collaborative online international learning activity in continuing education for practicing nurses is a viable strategy that is consistent with the internationalization at home movement. Use of a qualitative descriptive evaluation approach when teaching prelicen-sure nursing students and educating practicing nurses provides effective international collaboration, promotes a global mindset, and provides an exemplar for professional development specialists to teach practicing nurses.

[
J Contin Educ Nurs.
2024;55(5):220–223.]
Analysis of the linearly extrapolated BDF2 fully discrete Modular Grad-div stabilization method for the micropolar Navier-Stokes equations
Authors: Zhang Yunzhang , Yong Xinghui
Published: April 2024

We investigate a fully discrete modular grad-div (MGD) stabilization algorithm for solving the incompressible micropolar Navier-Stokes equations (IMNSE) model, which couples the incompressible Navier-Stokes equations and the angular momentum equation together. The mixed finite element (FE) method is applied for the spatial discretization. The time discretization is based on the BDF2 implicit scheme for the linear terms and the two-step linearly extrapolated scheme for the convective terms. The considered algorithm constitutes two steps, which involve a post-processing step for linear velocity. First, we decouple the fully coupled IMNSE model into two smaller sub-physics problems at each time step (one is for the linear velocity and pressure, the other is for the angular velocity), which reduces the size of the linear systems to be solved and allows for parallel computing of the two sub-physics problems. Then, in the post-processing step, we only need to solve a symmetrical positive determined grad-div system of linear velocity at each time step, which does not increase the computational complexity by much. However, the post-processing step can improve the solution quality of linear velocity. Moreover, we obtain unconditional stability, and error estimates of the linear velocity and angular velocity. Finally, several numerical experiments involving three-dimensional and two-dimensional settings are used to validate the theoretical findings and demonstrate the benefits of the modular grad-div (MGD) stabilization algorithm.
Diversité des pierres dans la construction grecque antique : une approche géologique et statistique appliquée à des sites archéologiques du Golfe de Corinthe, Grèce
Authors: Vals Marilou de , Moretti Isabelle
Published: April 2024

Cette étude est une comparaison de l’usage de la pierre dans 34 sites archéologiques de la région du Golfe de Corinthe (Grèce), en activité entre le vie et le ier siècle avant J.-C. Dans chaque site, le nombre de faciès et les proportions de chacun ont été obtenus. On observe une faible diversité de pierre (4-5) avec une prépondérance des faciès locaux et régionaux, très largement majoritaires en volume. Cependant, le site de Delphes apparait comme une exception : 13 faciès allochtones représentent presque 50 % du volume total. Ces premiers résultats montrent l’intérêt d’une approche quantitative, à pondérer avec les données historiques et la géologie locale.
Participatory Intervention in Eliminating Harmful Traditional Practices
Authors: Tella Didunloluwa O.
Published: April 2024

Concerning female genital mutilation practice in Africa, much of the abolition approach has focused on mass-mediated approaches: heavy reliance on mass campaigns and enlightenment programs in the affected communities. However, little or no attention has been given to the cultural adherents/perpetrators of this practice. Thus, in order to achieve a pragmatic and sustainable outcome regarding this practice, this chapter intends to broaden the theoretical discourse (democratic participant theory), seeking to highlight participatory interventions to put an end to this harmful traditional practice in selected African countries (Nigeria and South Africa). Primarily, it intends to explore the concept of participation and dialogue by incorporating the concerted effort of all stakeholders, particularly that of the cultural adherents/perpetrators of this practice. Thus, in order to achieve a colossal decline in female genital mutilation in Africa, active participation/involvement of cultural adherents is pertinent.
Advanced Shut-Down / Start-Up Analysis for Gas Hydrate Prevention in Subsea Production Systems
Authors: Dalla L. F. R. , Zerpa L. E. , Koh C. A.
Published: April 2024

This study introduces an advanced method for enhancing the post-processing of transient multiphase flow simulations, explicitly addressing the determination of Cool-Down Time (CDT), the time that the production system takes to reach the hydrate region, which is crucial for managing gas hydrate flow assurance issues in offshore production systems. The post-processing functions that have been developed analyze the subcooling independently for gas, oil, and water phases, estimating the subcooling evolution over time for each phase. The effect of different shut-in types on the CDT and subcooling evolution is also discussed. Finally, the method was applied to two typical subsea satellite production tiebacks, providing several insights into gas hydrate potential risks in the system during transient operations. A reliable and detailed analysis of the subcooling evolution and cool-down time enables the design of hydrate-safe operations of subsea production systems.
Application Models of New Technologies for Autonomous Inspection and Operation of Subsea Systems
Authors: Sewald B. F. , Britto A. J. R. , Bastos M. X. , Silva. R. P. , Fagundes H. C.
Published: April 2024

The subsea inspection plays a primary role in the integrity management of subsea assets. A wide variety of equipment, such as wet Christmas Trees (XMT), Pipes, Umbilical's, Mooring Lines and Manifolds are periodically inspected. The inspection frequency depends on the type of equipment and the boundary conditions applied to them, being usually based on the risk associated within the operation of the subsea assets.

The subsea system integrity management plan consists of activities such as visual inspections, functional test of safety valves, measurement of electrochemical potential, measurement of Pipe thickness and pressure tightness test of safety valves. These operations have been traditionally carried out by RSV vessels (ROV Support Vessel), which require around 40 people on board and up to 10m3/day of diesel. In a context of great demand for reducing POB (People on Board), and so the human exposure to risk, and also the urgency for GHG (Green House Gases) emission reduction, the market has been pushed to develop new inspection technologies.

The field operator, strategically aligned with this vision, has been supporting, through R&D projects, the development of the AUV for their challenging scenarios.