bluuebunny/crossref_metadata_2025 huggingface dataset:
The effectiveness of α1-blockers on uroflowmetry results in patients with Benign Prostatic Hyperplasia (BPH)
Authors: Pramana Ida Bagus Putra , Nyoman Gede Prayudi  , Tirtayasa Pande Made Wisnu , Yudiana I Wayan , Santosa Kadek Budi , Duarsa I Gede Wirya Kusuma
Published: August 2024

Background: The incidence of benign prostatic hyperplasia (BPH) increases in patients aged over 50 years. Currently, α1-blocker drugs are routinely prescribed to patients with BPH. One of the evaluations that is often used to assess the success of a patient's treatment with medication is a uroflowmetry examination. This study aimed to assess the effectiveness of administering α1-blockers on uroflowmetry results, specifically Q-max, voided volume, and post-void residual volume (PVR).
Methods: This prospective observational cohort study involves patients with BPH who received α1-blocker therapy at one hospital. The uroflowmetry data analyzed includes the Q-max value, voided volume, and PVR, measured before and after one, two, and three months of treatment. The data were analyzed using SPSS version 21.0.
Results: From the results, it was found that there was a significant improvement in Q max, voided volume (VV), and post-void residual volume (PVR) before treatment compared to 1 month after treatment and 3 months after treatment, specifically Qmax 8.86±1.87 ml/sec vs. 11.14±1.97 ml/sec vs. 14.02±1.75 ml/sec (p < 0.05), voided volume 142.45±20.42ml vs. 175.51±32.54 ml vs. 204.33±15.88 ml/sec (p < 0.05), PVR 60.95±13.63 ml vs. 50.92±12.32ml vs. 33.76±14.99 ml (p < 0.05).
Conclusion: Administering α1-blocker drugs to patients with benign prostatic hyperplasia significantly improves Q-max, voided volume, and PVR within one month of treatment, with maximum results observed after three months.
Fear not
Authors: Baliber-Duallo Rheamy
Published: August 2024

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The Neurotheology of Contemporary Spirituality
Authors: Nenadalová Jana , Geertz Armin W
Published: August 2024

The Varieties of Spiritual Experience: 21st Century Research and Perspectives, by David B. Yaden and Andrew B. Newberg. Oxford: Oxford University Press, 2022. x + 430 pages, £26.49. ISBN: 9780190665678
Pemaknaan Kembali QS. Al-Hasyr :18 sebagai Tujuan Pendidikan Islam yang Adaptif dalam Menyongsong Generasi Khairu Ummah
Authors: Fathur Rahman  , Ahmad Yusam Thobroni  , Abdillah Theofany Farozdaq
Published: August 2024

Q.S Al Hasyr : 18 adalah salah satu surat yang membahas tentang ketaqwaan kita kepada Allah serta perbuatan kita di masa lalu dan bagaimana kita memperbaikinya di masa yang akan datang, pemaknaan ayat ini bisa berlaku dalam segala bidang, khususnya di dalam dunia pendidikan Islam. Tujuan dari penelitian ini adalah untuk mengetahui pemaknaan kembali Q.S Al Hasyr : 18 tentang tujuan pendidikan Islam yang adaptif dalam rangka menyongsong generasi Khairu Ummah. Metode yang di gunakan dalam penelitian ini yaitu metode penelitian kepustakaan (Library Research) dengan menggunakan pendekatan metode tematik (metode tafsir maudhui), hasil dari penelitian ini adalah bahwasanya mayoritas beberapa mufassirin berpendapat di dalam Q.S Al Hasyr : 18 menerangkan tentang Konsep perencanaan, pengorganisasian, evaluasi dan tujuan di dalam dunia pendidikan. Selain itu juga menerangkan tentang bagaimana menjadi manusia yang bertaqwa dan bermuhasabah dari masa lalunya agar menjadi manusia yang Khairu Ummah.
Prinsip Manajemen Pendidikan Islam
Authors: Sahudi
Published: August 2024

Penelitian ini bertujuan mendeskripsikan dan menganalisis 1) prinsip Manajemen Pendidikan Islam, sepuluh ciri/indikator iman dan akhlak, 2) prinsip Manajemen Pendidikan Islam (studi hadits sepuluh indikator iman dan akhlak), 3) penerapan sepuluh ciri/ indikator iman dan akhlak dalam Manajemen Pendidikan Islam.
Metode penelitian berbasis kepustakaan, dengan tahapan penelitian 1) mengumpulkan bahan penelitian, 2) membaca bahan kepustakaan, 3) membuat catatan penelitian, 4) mengolah catatan penelitian, dan 5) membuat kesimpulan. Studi hadits yang diterapkan dalam penelitian ini adalah menampilkan  1) sepuluh teks hadits dan sanad hadits yang berhubungan dengan sepuluh indikator iman dan akhlak, 2) terjemah hadits, 3) biografi singkat sanad/ perawi hadits, 4) analisa hadits, dan 5) implementasi hadits dalam Manajemen Pendidikan Islam.
Adapun subyek penelitian dalam artikel ini adalah studi hadits sepuluh indikator iman dan akhlak sebagai salah satu prinsip Manajemen Pendidikan Islam.
Hasil utama penelitian adalah 1) sepuluh indikator iman dan akhlak merupakan prinsip dasar dan utama dalam menjalankan Manajemen Pendidikan Islam 2) dalam kajian hadits, sepuluh indikator iman dan akhlak telah dipesankan oleh Rasulullah SAW kepada para sahabat dan umatnya. Semua menjadi dasar untuk mewujudkan kehidupan yang harmoni, terkhusus dalam menjalankan Manajemen Pendidikan Islam, 3) dalam Manajemen Pendidikan Islam, sepuluh indikator iman dan akhlak merupakan konsep-konsep yang memegang peran penting dalam membentuk sikap dan perilaku siswa yang positif. Oleh karena itu, penerapannya harus dilakukan secara bersama-sama oleh stake holder.
Acehnese Language Addressing System: A Sociolinguistic Study in Indrapuri, Aceh Besar
Authors: Yanti Nurlayli , Helmi Rahil , Payana Wita Dwi
Published: August 2024

This research aims to analyze the sociolinguistic aspects of the system of addressing terms in Acehnese in Indrapuri District, Aceh Besar. This study focuses on the complexity of language and variations in how to greet each other in AL, with an emphasis on social and linguistic aspects. In this study, the complexity referred to is the complexity or variations found in a particular language in an area. This research uses descriptive qualitative research, where the focus of the research is on exploring the social situation that will be studied thoroughly. The population used was native AL speakers, consisting of 15 respondents who lived in Indrapuri District, Aceh Besar Regency. The selected respondents spread across six villages, including Ulee Ue, Mon Alue, Cureh, Groet Baro, Seulangai, and Seuramoe. The respondent selection technique used purposive sampling, with the condition that the informant had intact speech organs, including complete teeth, and had lived in the Indrapuri area for more than ten years. The research instrument used was a questionnaire list of addressing terms that had been formulated. Data was collected through two methods: observation and questionnaire distribution to each respondent. The data is classified based on types and factors. The results of this research show that there are six types of addressing terms, including kinship terms, non-kinship terms, religious terms, occupational terms, pronouns, and proper names. Factors that create variations in addressing terms in AL include politeness, gender, family lineage (noble status), marital status, religion, and social status.
Dynamics and implications of ROS in marine systems
Authors:   ,   Massachusetts Institute of Technology, Taenzer lina ,   Woods Hole Oceanographic Institution
Published: August 2024

The reactive oxygen species (ROS), superoxide and hydrogen peroxide, play critical roles across diverse marine ecosystems, influencing redox chemistry and organismal health. The distribution and concentration of these compounds in the oceans may serve as important controls for various biogeochemical cycles. The contrasting physiological nature of ROS, serving as both integral compounds for cellular processes such as signaling and growth while inducing oxidative cell damage at elevated concentrations, has made interpretation of their roles in organismal and ecosystem health challenging. Despite the potential for these ROS to provide unique insights into the intricate interactions occurring at the interface between life and its surrounding environment, critical gaps in our understanding of these compounds in marine systems exist. In this thesis I explored two aspects of marine ROS. The first part is focused on advancing our understanding of the distribution of superoxide in the sea. As part of a multidisciplinary team, I developed a submersible chemiluminescent sensor (SOLARIS) capable of measuring ROS in situ to ocean depths greater than 4,000 meters. With the use of SOLARIS, I discovered that a broad diversity of sponges and corals are local hotspots of superoxide at depth. Then, I studied the distribution of superoxide in the stratified water column of the Baltic Sea and found large subsurface maxima in the aphotic zone. In the second part of this thesis, I probed the use of hydrogen peroxide as a monitoring agent of organismal health. I measured hydrogen peroxide and bromoform production by two seaweed species exposed to different stressors. An analysis of these signals suggests that hydrogen peroxide could serve as a non-invasive chemical signature for stress in seaweed meadows and farms. Lastly, I characterized hydrogen peroxide associated with different coral species during a Stony Coral Tissue Loss Disease transmission experiment. I determined that hydrogen peroxide does not predict infection before lesions are visible, thus hindering its utility as an early-stage signature of disease within corals. Altogether, this thesis extends our perspective on the distribution and controls on ROS in various marine systems and provides a baseline for using ROS dynamics to monitor organismal health.
The response of the pepper with and without Me1 gene to Mi-1.2-virulent Meloidogyne incognita (Kofoid & White,1919) (Tylenchida: Meloidogynidae) isolates
Authors: Aksan Ahmet Kaan , Özalp Tevfik , Devran Zübeyir
Published: August 2024

Root-knot nematodes are important organisms that infect vegetables. Due to the intense use of Mi-1.2, virulent populations that break resistance have become widespread and have become an important factor limiting the use of this gene. Me1 resistance gene on pepper provides resistance against Meloidogyne arenaria (Neal, 1889) Chitwood, 1949 Meloidogyne incognita (Kofoid & White,1919) Chitwood, 1949 and Meloidogyne javanica (Treub, 1885) Chitwood, 1949 (Tylenchida: Meloidogynidae) species. However, there is limited information on the effectiveness of the Me1 gene against Mi-1.2 virulent populations. Therefore, it is important to know the reaction of pepper cultivars carrying the Me1 resistance gene against Mi-1.2 virulent populations. In this study, the response of resistant pepper cultivar MT-01 F1 (bearing Me1) and susceptible pepper cultivar Safran F1 against both Mi-1.2 natural virulent M. incognita isolates and Mi-1.2 selected virulent M. incognita isolate was investigated under controlled conditions. This study was conducted in Akdeniz University Faculty of Agriculture Department of Plant Protection Nematology Laboratory in 2021. All isolates caused many egg masses and galls on the resistant tomato cultivar Seval F1 as expected, and the susceptible pepper cultivar Safran F1. Five isolates were found to cause egg masses and gall formation, while the V3 isolate did not multiply on the resistant pepper cultivar MT-01 F1. The results showed that pepper cultivars carrying the Me1 gene exhibited different responses against Mi-1.2 virulent isolates.
The COVID-19 Pandemic and Family Economic Well-being: Evidence from the Survey of Consumer Finances
Authors: Goodman Sarena , Li Gina , Moore Kevin , Volz Alice Henriques
Published: August 2024

The COVID-19 pandemic caused severe disruptions to the U.S. labor market and economic activity. We establish connections between family experiences of the pandemic, their income under normal conditions, and their later economic well-being using the 2022 Survey of Consumer Finances. By their interview, one-third of families experienced net employment declines, one-third had teleworked, and one-fifth had significant COVID-19-related health events. These experiences strongly reflected families’ positions in the income distribution, with lower-income families bearing the brunt. They also tightly predict income and wealth after the initial disruptions, signifying that the pandemic economy likely amplified pre-pandemic differences and fostered new divides.
Inframarginal Borrowers and the Mortgage Payment Channel of Monetary Policy
Authors: Ringo Daniel
Published: August 2024

Despite the widespread use of fixed-rate mortgages in the United States, I show that monetary policy is effectively passed through to aggregate outstanding mortgage debt service. Using credit bureau, lender, and servicer data on mortgage payments and originations and exogenous monetary policy shocks, I estimate a mortgage rate semi-elasticity of payments over 10. Inframarginal borrowers---households whose choice to buy a home or refinance does not depend on the particular monetary policy decision under consideration---are the most important conduit, explaining over half of the pass-through. Consistently large flows of inframarginal borrowing relative to the stock of outstanding debt account for the strength of this channel. Households with adjustable-rate mortgages and marginal refinancers, the focus of much of the literature on monetary policy's effect on mortgage borrowers, each explain about 20 percent of the pass-through. I show the mortgage payment channel induces a lag in the operation of policy, as the cumulative effects on debt service build over time in response to persistent shocks to longer-term rates. Estimated magnitudes suggest that mortgage payments are a primary channel by which monetary policy affects consumption.
An Expansion Of Liberty
Authors: Scott Gavin
Published: August 2024

This primary source analysis examines the relationship between church and state in early American society from the point of view of the anonymous pamphlet, The Freeman’s Remonstrance Against an Ecclesiastical Establishment, being some remarks On a Late Pamphlet, Entitled The Necessity OfAn Established Church In Any State; By A Freeman Of Virginia. written in 1777. The Freeman uses many ideas from the American Revolution such as American unity, the expansion of liberty, and expansion ofequality to argue for disestablishment. This topic is important because of the ever-evolving debate over church and state in the United States.  
Association between sub-cortical beetles, mites, and ophiostomatoid fungi on trees in South African Afromontane forests
Authors: Musvuugwa Tendai , Dreyer Leanne , Roets Francois
Published: August 2024

Sub-cortical beetles and mites contribute to tree mortality by creating wounds and by spreading potential pathogens. Here we elucidate associations between sub-cortical beetles, mites, and ophiostomatoid fungi from trees in Afromontane forests in South Africa. Bark and wood samples were collected from native tree species and exotic Pinus radiata and Acacia mearnsii that showed signs of sub-cortical beetle activity, or from wounds on storm-damaged trees. Ophiostomatoid fungi, a group that contains numerous tree pathogens, were isolated from beetles that emerged from samples, their galleries, phoretic mites on these beetles, and from wounds and wound-associated mites. Fungal isolates were identified using multiple DNA markers. Twenty sub-cortical beetle, 22 mite and 16 ophiostomatoid fungal species were recovered from only a few native and exotic host tree species. Three fungal species are likely undescribed despite increased focus on this ecologically and economically important group worldwide. Significantly, some mites and fungi were isolated from native and non-native hosts. Wound-associated fungi and mites were less host-specific than sub-cortical beetle-associated taxa. We highlight the rich and still unexplored symbioses between sub-cortical beetles, mites, and ophiostomatoid fungi in Afromontane forests and provide a foundation for future studies on the ecology of these important organisms.
An Integrative Machine Learning Approach in Detecting Gene Networks Predicting Liver Cancer Incidence and Survival
Authors: Stephan  , Murshalina  , Md Tamzid Islam  , Mihaela Sardiu  , Yanming Li
Published: August 2024

Introduction. Liver cancer (LC) is one of the most common types of cancer and the third largest cause of cancer-related deaths globally. Although there is no known cause of LC, the disease has some associated risk factors. Studies have also linked genetic mutations to LC. Patients who receive early diagnosis have a five-year relative survival rate of ~36%, whereas ~3% for late diagnoses.Methods. In this study, we employed a novel machine learning technique called netLDA which initially identified predictive strong DE genes and used as them hubs genes to identify coregulating genes that may only exhibit marginally weak DE effects. The detected genes form predictive gene networks (PGNs), which are used to make predictions.Results. Our study detected previously identified LC occurrence susceptibility strong genes; GPC3, STMN1 and TCF19. Potential biomarker genes for LC occurrence such as MT1E and PLVAP were detected as co-regulating weak genes. In our one-year survival study, SPP1 and ADH4 were detected as strong genes whilst MFAP4 was identified as novel co-regulating weak gene. The PGNs achieved an AUC of about 1.00 in our case-control study and 0.77 in our one-year survival study. Some of the detected genes overlapped with some significant LC related pathways to provide additional layers of biological significance.Conclusions. With our study, the identified predictive genes can propel studies into understanding the underlying mechanisms for LC development and prognosis. These identified biomarker genes can be used as new therapeutic targets by industries in the development of new drugs for LC.
Erken Okuryazarlık Eğitim Programı’nın 60-69 Aylık Çocukların Erken Okuryazarlık Becerilerine Etkisinin İncelenmesi
Authors: Ertekin Betül Dilşad , Çamlıbel Çakmak Özlem
Published: August 2024

Bu araştırmada, araştırma kapsamında geliştirilen Erken Okuryazarlık Eğitim Programı’nın 60-69 aylık çocukların erken okuryazarlık becerileri üzerindeki etkisinin incelenmesi amaçlanmıştır. Çalışma grubu 12 deney, 12 kontrol grubu olmak üzere toplam 24 çocuktan oluşmaktadır. Araştırmada ön test- son test kontrol gruplu yarı deneysel desen kullanılmıştır. Veri toplama aracı olarak "Erken Okuryazarlık Becerilerini Değerlendirme Aracı" kullanılmıştır. Erken Okuryazarlık Eğitim Programı deney grubundaki çocuklara araştırmacı tarafından haftada beş gün olmak üzere dört hafta boyunca yaklaşık 40 dakikalık etkinlikler şeklinde uygulanmıştır. Kontrol grubunda yer alan çocuklar ise öğretmen tarafından verilen eğitime devam etmiştir. Eğitim programının tamamlanmasının ardından hem deney hem kontrol grubuna son testler uygulanmıştır. Araştırmadan elde edilen bulgulara göre, ön test sonuçları arasında anlamlı bir farklılık görülmeyen deney ve kontrol grubunun son test sonuçları arasında anlamlı bir farklılık görülmüştür. Deney grubunun sesbilgisel farkındalık, yazı farkındalığı, öyküyü anlama, görselleri eşleştirme ve yazı yazma öncesi beceriler alt testlerinin tamamında ön test ve son test sonuçları arasında anlamlı bir farklılık görülürken; kontrol grubunun yalnızca yazı yazma öncesi beceriler alt testinde anlamlı bir farklılık görülmüştür. Kalıcılık testi sonuçlarına göre deney grubunda elde edilen sonuçların en az üç hafta kalıcılık gösterdiği görülmüştür.
Özel Öğrenme Güçlüğü Olan Öğrencilerin Matematik Problemi Çözme Becerilerinde Şemaya Dayalı Öğretim Stratejisinin Etkililiği
Authors: Şen Sena Gülsüm , Yıkmış Ahmet
Published: August 2024

Matematik problemi çözme becerilerinin öğretimi, okul müfredatının en kritik yönlerinden birini temsil etmektedir. Özel öğrenme güçlüğü olan öğrenciler, okul nüfusunun %5 ila %15' inde görülmekte ve farklı davranış çeşitlilikleriyle kendini göstermektedir. Öğrencilerin matematik problemi çözerken yaşadıkları zorluklar değişebilmekte ve bu durum, genel müfredatta normal akranlarıyla rekabet etme yeteneklerini negatif yönde etkileyebilmektedir. Özel öğrenme güçlüğü olan öğrencilerin görülme oranının yüksek olması ve uygun öğretim yöntemleri uygulanmadığı zaman olumsuz etkilerin yaşam boyu gözlemlenebileceği riski göz önüne alındığında, riskleri en aza indirmek ve koruyucu faktörleri en üst düzeye çıkarmak için uzman kişiler tarafından verilen etkili önleme, değerlendirme ve öğretim sistemlerinin oluşturulması önemli görülmektedir. Bu bağlamda çalışmada, özel öğrenme güçlüğü yaşayan öğrencilere yönelik olarak geliştirilen animasyonla desteklenen şemaya dayalı bir stratejinin, matematik problemlerini çözme üzerindeki etkisini belirlemek amaçlanmıştır. Araştırmada, tek denekli araştırma yöntemlerinden "Denekler Arası Yoklama Denemeli Çoklu Yoklama Modeli" kullanılmış ve üç öğrenci yer almıştır. Ulaşılan sonuçlara göre, öğrencilerin matematik problemlerini çözme becerileri ile animasyonla sunulan şemaya dayalı strateji arasında işlevsel bir ilişki bulunmaktadır. Ek olarak, animasyonla desteklenen şemaya dayalı öğretim stratejisinin, öğrencilerin matematik problemi çözme becerilerini öğretim sonrasında 5, 10 ve 15 gün boyunca sürdürdükleri bir süreçte etkili olduğu tespit edilmiştir. Elde edilen verilere dayanarak, bu stratejinin uygulanmasıyla öğrencilerin matematik becerilerindeki gelişimin uzun vadeli etkilerini değerlendirmek ve ileri araştırmalara yönelik potansiyel alanları belirlemek amacıyla çeşitli öneriler üzerinde tartışılmıştır.
7. Sınıf Sosyal Bilgiler Ders Kitabının Çokkültürlülük Bağlamında İncelenmesi
Authors: Doğan Mustafa , Ablak Selman , Akcan Ceylan
Published: August 2024

: Bu araştırmada 7. sınıf sosyal bilgiler ders kitabında yer alan çokkültürlülük konuları ele alınmıştır. Araştırma nitel araştırma yöntemlerinden biri olan doküman analizi ile gerçekleştirilmiştir. Araştırma materyali olarak 2023-2024 eğitim öğretim yılında Ekoyay Yayınevi tarafından 7. sınıflar için yayımlanan ders kitabı kullanılmıştır. 7. sınıf ders kitabında yer alan çok kültürlülük konuları içerik analiziyle incelenerek “Farklı Kültürleri Tanımaya Yönelik Farkındalık, Farklı Kültürlerin Bir Arada Yaşaması, İnsan Hak ve Özgürlükleri Bağlamında Çok Kültürlülük” temaları oluşturulmuştur. Bu temalar kendi içinde alt temalara göre sıralanmış, frekans ve yüzde değerleriyle gösterilerek tablo hâlinde sunulmuştur. Farklı kültürleri tanımaya yönelik farkındalık teması altında ‘Farklı Kültürler Arası Etkileşim’, Farklı kültürlerin bir arada yaşaması teması altında ‘Dini Hoşgörü’, İnsan hak ve özgürlükleri bağlamında çok kültürlülük teması altında ise ‘Düşünce Özgürlüğü’ alt temasının ilk sırada yer aldığı sonucuna ulaşılmıştır. Yapılan bu çalışmanın çokkültürlülük kavramına ilişkin farkındalık düzeyinin artmasına, sosyal bilgiler öğretiminde kullanılan ders kitaplarında çok kültürlülük gibi temel insan hak ve özgürlükleriyle ilgili güncel konulara daha fazla yer verilmesine katkı sunması beklenmektedir.
Örgün Eğitim Programlarının Deprem Eğitimi Açısından İncelenmesi
Authors: Can Esra , Çapuk Suat
Published: August 2024

Bu çalışmada, örgün eğitim programlarının deprem eğitimi açısından incelenerek mevcut durumun ortaya çıkarılması amaçlanmaktadır. Araştırmada nitel araştırma yöntemlerinden doküman analizi kullanılmıştır. Örgün eğitimde yer alan öğretim programlarının tamamı incelenmiş ve deprem eğitimine yönelik kazanımların yer aldığı Hayat Bilgisi, Sosyal Bilgiler, Fen Bilimleri, Afet Bilinci, Şehrimiz, İngilizce, Fizik ve Coğrafya derslerine ait öğretim programları ve ders kitapları örneklem olarak seçilmiştir. Öğretim programları ve ders kitaplarında deprem eğitimine yönelik kazanım ve içeriklerin analizinde betimsel analiz kullanılmıştır. Araştırmanın bulgularına göre deprem eğitimi ile ilişkili 37 kazanım tespit edilmiştir. Ders kitaplarında deprem eğitimi ile ilişkili içeriklerin afet ve acil durum yönetiminin aşamalarına göre analizi sonucunda en fazla zarar azaltma ve önleme ile hazırlık aşamasına yönelik içeriklerin yer aldığı, müdahale ve iyileştirme aşamasından çok az bahsedildiği görülmüştür. Kazanımların taksonomik sınıflandırılması incelendiğinde 37 kazanımın tamamının bilişsel alanda yer aldığı tespit edilmiştir. Deprem eğitimi ile ilişkili kazanımların bilişsel alanın daha çok alt düzey basamaklarında bulunduğu, üst düzey basamaklarda çok az kazanımın yer aldığı sonucuna varılmıştır. Eğitim Programlarında deprem eğitimine yönelik içeriklere yer verilmesi için önerilerde bulunulmuştur.
Тонкослойная хроматография метилированных производных алкилбензолсульфонатов натрия в анализе воды методом ГХ-МС
Authors: Никонова Алёна Александровна , Рохина Елена Филипповна , Глызина Ольга Юрьевна , Дылгерова Светлана Дамбаевна , Чиндявская Анна Николаевна , Рохин Александр Валерьевич , Пройдаков Алексей Гаврилович
Published: August 2024

Алкилбензолсульфонаты натрия (АБС) являются наиболее распространенными анионными синтетическими поверхностно-активными веществами (АСПАВ) и загрязнителями вод, способными вызывать как острое так и хроническое токсическое воздействие на гидробионты. Cелективное определение алкилбензолсульфонатов натрия как отдельного класса АСПАВ в сложных природных матрицах возможно методом газовой хроматографии с масс-спектрометрическим детектированием (ГХ-МС) в форме метиловых эфиров алкилбензолсульфокислот (МЭ АБСК). С целью очистки экстрактов и концентрирования аналитов изучено поведение АБС и МЭ АБСК в условиях восходящей высокоэффективной тонкослойной хроматографии (ТСХ) с использованием пластин «Kieselgel 60 F254» и «Sorbfil». В качестве подвижной фазы предложено использование смеси растворителей н-гексан : метанол в соотношении 23 : 1 (по объему). В указанных условиях алкилбензолсульфонаты натрия остаются на линии старта, в то время как их производные (МЭ АБСК), полученные метилированием триметилортоформиатом в присутствии трифторуксусной кислоты (выход η=98%), образуют зоны, характеризующиеся значениями коэффициентов удерживания Rf = 0.62 и Rf = 0.71 на пластинах «Kieselgel 60 F254» и «Sorbfil» соответственно. Повторяемость оценки значений Rf охарактеризована среднеквадратичным отклонением 6.1 и 5.9% соответственно (n=16). Отмечена полнота экстракции (95.0-100.0%) аналитов с пластин методом нисходящей ТСХ ацетонитрилом. Показана применимость метода ТСХ для концентрирования аналитов и доочистки экстрактов на примере реальных проб воды. С помощью метода ГХ-МС с ионизацией электронным ударом найдены концентрации алкилбензолсульфонатов натрия в воде, отобранной в южной котловине озера Байкал с глубины 400 м (0.24±0.02 мкг/дм3) и в воде, полученной при таянии снега, отобранного со льда р. Крестовка в месте впадении ее в оз. Байкал в районе пос. Листвянка (31.1±1.0 мкг/дм3).
Диффузионная и химическая кинетика адсорбции метиленового голубого на кремнеземах, допированных ионами железа (III)
Authors: Титов Евгений Николаевич , Смальченко Дмитрий Евгеньевич , Лебедева Ольга Евгеньевна
Published: August 2024

Кремнеземы находят широкое применение в катализе, адсорбции, хроматографии. В последнее десятилетие растет их использование в медицине, однако для обеспечения биосовместимости необходимо модифицирование кремнеземов, простейшим вариантом которого является допирование катионами железа. В статье представлено исследование сорбционных характеристик кремнеземов, допированных катионами железа. Целью исследования являлась оценка влияния допирования ионами железа на кинетику адсорбции кремнеземами модельного сорбата метиленового голубого. Допированные кремнеземы синтезированы алкоксидным золь-гель методом при рН=1.5 и рН=5.0 с введением катионов железа в реакционную смесь в ходе гидролиза тетраэтоксисилана. Содержание железа в образцах составило 1.5, 2.3 и 3.8 атомных процентов. По результатам рентгенофазового анализа все образцы рентгеноаморфны. По форме изотерм низкотемпературной адсорбции азота все образцы отнесены к микропористым. Площадь удельной поверхности образцов и общий объем пор несколько снижаются с ростом содержания железа в образцах. Адсорбция метиленового голубого производилась при температуре 25, 30 и 35°С. Кинетические кривые адсорбции проанализированы при помощи моделей диффузионной кинетики: модели Бойда (внешнедиффузионный процесс) и модели Морриса-Вебера (внутридиффузионный процесс). Также данные кинетических исследований были проанализированы с использованием кинетических моделей псевдопервого порядка (модель Лагергрена) и псевдовторого порядка (модель Хо и Маккея). Установлено, что все образцы характеризуются смешаннодиффузионным течением сорбционного процесса. Кинетику адсорбции адекватно описывает модель псевдовторого порядка.
Collection and shipment of specimen for single-nuclei RNA sequencing (snRNA-Seq) v1
Authors: Robinson Laura
Published: August 2024

These samples are part of the JAX-Sen project in the SenNet Consortium. Here we provide details on specimen collection and shipment to the Robson laboratory at The Jackson Laboratory for Genomic Medicine (JAX-GM) in Farmington, CT for its processing for single-nuclei RNA-sequencing (snRNA-seq).
Preparation of qPCR standards for AAV titering v1
Authors: Marongiu Roberta , Unda Santiago , G. Kaplitt Michael
Published: August 2024

qPCR standards for AAV tittering document annex to protocol "AAV Purification Protocol with Iodixanol gradient"
PFF seeding in iPSC-derived cortical neurons v1
Authors: Lam Isabel , Ndayisaba Alain , Khurana Vikram
Published: August 2024

PFF seeding in iPSC-derived cortical neurons_reformatted
Applications of Information Systems within Supply Chain Management
Authors: Hattar Issa Zayed
Published: August 2024

Information system (IS) is the advent of technology which has helped many sectors of business in earning greater revenue and becoming sustainable in the long-term approach. Information systems are also strengthening the supply chain management (SCM) and the global context for better delivery in meeting consumer demands and generating profits. The study mainly highlights the internet applications which are applicable within the supply chain and the information sharing as well as communicational improvement which has been implemented to the SCM. Additionally, the information system has also enhanced the consumer service, reduction of cost during procurement, and accessibility to worldwide market in the supply chain.
COVID-19 impact in sourcing in Global Value Chains
Authors: Dienes Balázs Bence , Qorri Dejsi , Felföldi János
Published: August 2024

This study explores the impact of COVID-19 on Global Value Chains (GVCs) using the Eurostat dataset, focusing on trade barriers and the difficulty of sourcing raw materials or intermediate goods from local and international suppliers. Using a contingency table grouped by country, we can see how raw material constraints and COVID-19’s GVCs affect many countries. The study uses Chi-square test to determine if these factors have a significant association. The data imply that foreign sourcing presents less challenges for suppliers than domestic sourcing, stressing the need of examining the consumer behaviour under uncertainties to develop GVCs resilience. The findings show a statistically significant link between barriers related to raw material and the effect level of COVID-19 in global value chains across all countries analysed. Suggesting that it is unlikely to have happened by random chance alone, highlighting the importance of addressing trade barriers and adapting to the impact of COVID-19 within global value chains.
Ecosystem Model on Adaptive MOOC in Higher Education
Authors: Alwi Ahmad Chafid , Priyanto Priyanto , Dwiningrum Siti Irene Astuti , Nurlaily Akhsin , Raharjo Amrih Setyo
Published: August 2024

This research aims to develop an adaptive MOOC ecosystem in universities. This study involved development research using the 4-D model, which consists of defining, designing, developing, and disseminating. The results indicate that in developing a MOOC ecosystem, it is necessary to conduct an in-depth analysis of users to find out what structures are needed. The context of MOOCs by companies is undoubtedly different from that of universities. As an educational institution, its stakeholders involve university leaders and researchers from lecturers. In the initial design, it is necessary to test user characteristics so that the MOOC system can make decisions on learning recommendations. We involved metacognitive testing and categorize so that users can learn to the fullest. In its application, validity tests were performed on experts to assess the product from development and on users. The test results showed excellent results. This ecosystem has also been disseminated to users and received a very good response. Moreover, several universities in Indonesia have the status of PTN-BH, which demands financial independence, so MOOC can be one of the breakthroughs to acquire income generation. Keywords: adaptive MOOC, MOOC ecosystem, higher education
Implementasi artificial bee colony pada mix fleet vehicle routing problem (MFVRP) untuk optimalisasi pendistribusian produk
Authors: Wulandari Elis Dwi , Satyananda Darmawan
Published: August 2024

Mix Fleet Vehicle Routing Problem (MFVRP) merupakan bagian dari permasalahan Capacitated Vehicle Routing Problem. Tujuan utama dari MFVRP adalah meminimalisasi jarak tempuh dan banyak kendaraan dengan memperhatikan setiap kendaraan yang memiliki kapasitas berbeda. Artificial Bee Colony merupakan algoritma yang didasarkan kecerdasan berkelompok dari lebah dalam mencari sumber makanan. Terdapat tiga bagian dalam kelompok lebah yaitu Lebah Pekerja (Employed), Lebah Penjaga (Onlooker) dan Lebah Pengintai (Scout). Implementasi Algoritma Artificial Bee Colony untuk memudahkan menyelesaikan permasalahan MFVRP menggunakan Borland Delphi 7.
Algoritma genetika pada split delivery vehicle routing problem (SDVRP) dan implementasinya
Authors: Rahayuningsih Farid Tri , Wahyuningsih Sapti , Yasin Mohamad
Published: August 2024

Split Delivery Vehicle Routing Problem (SDVRP) yaitu perluasan VRP dengan tiap customer dapat dilayani lebih dari satu kali yang dikarenakan jumlah permintaan customer sama besar atau lebih besar dengan kapasitas dari kendaraan dan dilayani dengan kendaraan yang berbeda untuk meminimalkan biaya pendistribusian. Algoritma genetika adalah suatu jenis struktur pencarian nilai optimal berdasarkan peniruan proses evolusi biologi. Algoritma genetika pada SDVRP terdiri dari enam langkah, yaitu teknik pengkodean, pembangkitan populasi awal, pembentukan rute berdasarkan kendala kapasitas, perhitungan nilai fitness kemudian seleksi pindah silang dengan metode Partial-Mapped Crossover (PMX) dan mutasi. Untuk mempermudah dalam menyelesaikan SDVRP dengan algoritma genetika maka direpresentasikan dalam program komputer menggunakan Borland Delphi 7. Meskipun program sangat membantu mempermudah dalam menghitung jarak minimum pada permasalahan pendistribusian, namun program ini memiliki kelemahan yaitu lama proses perhitungan dipengaruhi oleh banyak populasi dan maksimum generasi yang diberikan.
Implementasi kurva kaplan-meier dan regresi lognormal terhadap lama pengobatan pasien diabetes mellitus dan faktor-faktor yang mempengaruhinya ( Studi Kasus di RSI Malang Unisma )
Authors: Rohmawati Ruly , Permadi Hendro
Published: August 2024

Penelitian ini bertujuan menganalisa hasil kurva Kaplan-Meier untuk faktor dugaan yang mempengaruhi lama pengobatan pasien diabetes mellitus, serta memperoleh model regresi Lognormal dan mengetahui faktor yang paling berpengaruh terhadap lama pengobatan pasien diabetes mellitus di RSI Malang Unisma. Hasil kurva Kaplan-Meier menunjukkan bahwa pada kurva survival, cum survival semakin rendah seiring dengan semakin lamanya pengobatan pasien yang berarti bahwa semakin lama pengobatan pasien, maka peluang kondisi pasien membaik semakin kecil. Sedangkan dari kurva hazard dapat dilihat bahwa cum hazard semakin tinggi seiring dengan semakin lamanya pengobatan pasien yang berarti bahwa semakin lama pengobatan pasien, maka peluang pasien menjalani pengobatan semakin besar. Sedangkan dari metode regresi Lognormal diperoleh model regresi  dengan faktor yang mempengaruhi lama pengobatan pasien diabetes mellitus  adalah , yaitu kadar glukosa pasien diabetes mellitus.
Islamic Aesthetic Philosophy in Arabic Calligraphy
Authors: Kholili Hasib
Published: August 2024

This article describes the aesthetic value of Arabic calligraphy or khat. This study of khat art's aesthetic value aims to reveal the model and philosophy of Arabic calligraphy as an Islamic work of art. The analysis in this article employed descriptive methods and two approaches, notably philosophical and historical. The model and philosophy of a work of Islamic art are influenced by the aqliyyah influence of an artist, according to the analysis. Because religious values influence an artist's perspective, his artwork contains an aesthetic philosophy that is also religious. For example, since the arrival of the muballigh from Arabia, the emergence of Islamic arts in the archipelago has been inextricably linked to the process and development of Islamization activities. The propagators of Islam use art and da'wah in their work. In a nutshell, physical and metaphysical beauty are both present in Arabic calligraphy. Physical beauty is pursued in the creation of calligraphy that has smooth and pleasing forms to the eye. The art form of calligraphy contains metaphysical beauty in the form of beautiful and good messages. These messages can be in the form of instruction (ta'limiyyah) or simply facts about da'wah.
جهود الشيخ الحاج محمد الأمين الكانمي البرنوي في تطوير الخط العربي في السودان الغربي
Authors: الدكتور زكريا محمد عبدالله
Published: August 2024

This modest brief research is about: The efforts of Sheikh Al-Hajj Muhammad Al-Amin Al-Kanimi Al-Barnawi in developing Arabic calligraphy in Western Sudan. The researcher chose this topic for many purposes, including: (1) The desire to raise the status of the Arabic language. (2) To highlight the effective attempt that Sheikh Muhammad Al-Amin Al-Kanimi was able to make in the field of Arabic calligraphy. (3) The researcher's longing to study Nigeria's Arabic productions. (4) Encouragement to try to trace the traces of that sheikh. As for the purposes of the research, there are: (1) Expanding the knowledge and intellectual level in the field of Nigerian Arabic calligraphy. (2) Shedding light on Sheikh Muhammad Al-Amin Al-Kanmi’s interest in the Arabic language in Nigeria in particular, and in West Africa in general. Then the research will follow the descriptive approach so as to follow the efforts of Al-Kanmi and express it in a quantitative and qualitative manner, to clarify the characteristics features, and to analyze the data and reach conclusions. The research obtained the following results: (1) Sheikh Muhammad Al-Amin Al-Kanmi was born in the year: one thousand seven hundred and seventy six (1776 AD), and he grew up in a house of knowledge, under the care of his father. Al-Kanimi learned the knowledge of Qur’an from his father (Muhammad Lenga), and the principles of Arabic and Islamic education, then continued to travel to different cities, including: Jerusalem, Mecca, Medina, Fez, Egypt, Tripoli, Qairawan, Tlemcen, and others. He learned the Islamic knowledge and language from its distinguished scholars so that he could navigate many types of knowledge and arts. (2) Al-Hajj Muhammad Al-Amin Al-Kanmi is one of the prominent figures of Arabic calligraphy who made a great contribution to the revitalization and development of Arabic calligraphy in the country of Nigeria, where he was able to impose many poems for various puposes, as well as editing vauablelettershe sent to the leader of Sokoto jihad (Sheikh Othman bin Muhammad Fodio), and the correspondences that he was able to carry out between him and the neighboring countries, and those between him and the King of England.
تعليم فن الخط في منظمة جمعية الخطاط بمعهد منبع العلوم بتا-بتا الإسلامي باميكاسان مادورا
Authors: Ali Makki  , Ahmad Fauzun Karim  , Utari Dwi Mayasari
Published: August 2024

Sheikh Shams Al-Din Al-Afkani held that the calligraphy was a single letter in its place and how it was formulated in a written composition or written in a written form. Of the importance of calligraphy: Calligraphy is not limited to the skill of drawing and writing alone, but it is related to spiritual insight. Calligraphy pleads to protect the heart, speech, ideas, and behavior of society. In learning precious social values ​​of following, imitation, competence, obedience, orderliness, benefit, and appreciating the production of others. Despite the great importance of calligraphy, unfortunately, its study and education is neglected and most people do not care about it. As well as the widespread research does not deal with much research and depth. This research presents to the readers to reveal the process of teaching calligraphy in the Calligrapher Association at the Institute of the Source of Sciences Pta-Pta Bamikasan Madura as a contribution to increasing the wealth of scientific research on the art of teaching calligraphy and its advantages and shortcomings. The researcher used for this research the approach of scientific research is qualitative research with the type of case study. The three methods of data collection are interview, observation and documentation. This scientific research has reached the conclusions that teaching the art of calligraphy in it takes place in three stages: pre-education, implementation of education, and evaluation of education. As for the advantages, most of them are dispensed for a long time and it is cheaper for the others. The shortcomings, including the lack of puberty to the maximum and perfection.
Experiencia de atención a mujeres víctimas de violencia en Consultorios Rosa. Cali, Colombia
Authors: Estrada Duque Yivi Yohana , Otálvaro Marin Liliana
Published: August 2024

Objective: To describe the care process received by women victims of gender violence in intimate partner relationships through the strategy of the Consultorios Rosa (hillside health networkESE and north health network ESE) in Cali during the period 2020 – 2022.
Methods: Was carried out qualitative research of a phenomenological type from the study on women victims of intimate partner violence. Through the development of semi-structured interviews, the experiences of health care in the pink office strategy, which operates in the primary care centers in Cali, Colombia, were analyzed.
Results: The violence against women in couple relationships was caused by multiple violent expressions that affect emotional, mental, and physical health and exposure to femicide. The Consultorios Rosa strategy represents an opportunity for women to make the initial recovery and can address the situation experienced and give it new meaning; however, the strategy is susceptible to improvements that restore women's rights in the health sector.
Conclusions: Women continue to be victims of psychological, emotional, physical, economic, and sexual abuse, experiencing violent situations in their relationships; all violent expressions affect their health, well-being, and life, evidencing emotional, mental, and physical consequences. Therefore, it continues to be a priority public health problem to intervene. Public health strategies play a crucial role in the recovery of women victims of violence. However, their scope is underestimated if the interventions are not accompanied by timely access to justice. Interdisciplinary and interinstitutional care is necessary to provide comprehensive services to women victims of violence from the health sector.
Quemados con pólvora durante la temporada decembrina: Efecto de la ley 670-2001 en Cali-Colombia
Authors: Tejeda-Puentes Doris Stella , Hernández Carrillo Mauricio , Londoño Oscar
Published: August 2024

Introducción: Las lesiones por pólvora generan altos costos socioeconómicos y daños ambientales. Se presenta un análisis, después de quince años de la emisión de una política nacional para evitar las lesiones por esta causa.
Objetivo: Describir el comportamiento de las lesiones relacionadas con el uso de pólvora durante las festividades decembrinas en Santiago de Cali-Colombia durante el período 2002-2016.
Métodos: Estudio descriptivo retrospectivo. Utilizando bases de datos secundarias del Observatorio Social y del SIVIGILA, se caracterizaron los casos de quemados por pólvora en la ciudad.
Resultados: Se identificaron 655 lesionados por pólvora en época decembrina, el 83% de los lesionados son hombres, el 43% menores de edad, siendo el grupo de 10 a 14 años el más afectado, se alcanzó una importante disminución en el grupo de la primera infancia. Las partes más afectadas fueron miembros superiores y cabeza.
Conclusión: La política ha tenido un impacto positivo para proteger a la primera infancia. Se recomienda una mayor difusión de la norma en el período pre decembrino y un fomento de la educación con enfoque de género, dirigida a la comunidad educativa (escolares, docentes y padres de familia) para incidir en costumbres patriarcales como el uso de pólvora para celebrar y en la disminución de quemados en otros menores de edad a fin de aumentar el impacto de la normatividad existente.
Die interkontinentale Reise als Selbstfindungsprozess in Herzogs Höhenflüge von Wolfgang Sréter
Authors: Majkiewicz Anna
Published: August 2024

Mobilität als gegenwärtiges Phänomen und ihre komplexen Auswirkungen werden von jüngsten AutorInnen literarisiert und ästhetisiert. Dadurch beteiligt sich die neueste Literatur aktiv an Debatten um Identitätskonzepte und Werte, die conditio humana erläutern. Die Antworten auf die Fragen, wo sich heute der Mensch in der Welt platziert und wie sich der Sinn seiner Existenz definieren lässt, werden anhand der (Krimi-nal-)Road-Story Herzogs Höhenflüge von einem deutsch-ungarischen Autor Wolfgang Sréter gesucht. Im weiteren wird auch die Rolle der Reise im analysierten Roman erklärt.
„Ein Я konnte ich mir nicht denken.“ Dimensionen des Liminalen in Sasha Marianna Salzmanns Roman Außer sich
Authors: Jaglewicz Magda
Published: August 2024

Der Beitrag analysiert das Konzept der Liminalität sowie dessen Bedeutung und Funktion in Sasha Marianna Salzmanns Roman Außer sich. Liminalität als ein Zustand des Dazwischenseins spielt eine entscheidende Rolle in diesem Text, in dem die Figuren verschiedene – sowohl physische als auch metaphorische – Grenzen und Schwellen überschreiten. Zu den Dimensionen des Liminalen gehören in Außer sich nationale und geschlechtliche Identitäten, physische Räume sowie postmemoriale Praktiken. Liminalität weist dabei ein transformatives Potenzial auf. Die Verortung der Figuren sowie ihres Selbst im Liminalen ermöglicht es Salzmann, konventionelle Vorstellungen von Identität, Zugehörigkeit und gesellschaftlichen Normen in Frage zu stellen. Wegen der starken Verankerung feststehender Zuschreibungen im Kollektivbewusstsein wird andererseits deutlich, dass liminale Erfahrungen sowohl Orientierungslosigkeit als auch das Gefühl der Prekarität der eigenen Identität zur Folge haben.
Virtual Reality and Gamification in Hospitality Education at Front Desk
Authors: Asmak Ismail Nurul Halimatul , B. Awwad Samer A. , Thinakaran Rajermani , Quah Wei Boon , Muniandy Mohana
Published: August 2024

Virtual reality (VR) is recognized as an intelligent and digital technology that has impacted numerous sectors and environments. VR in the classroom acts like a digital tool for the students and the teachers to achieve educational goals as it enhances understanding, critical thinking, visualization levels, and problem-solving skills. In addition, gamification as a motivational factor is integrated with VR. This study investigates the usage of VR and gamification in hospitality educational environment mainly at the front desk. This is to be beneficial to an individual's knowledge and abilities, which should be prioritized in the future, and that earlier experience should be given credit for future employability and education quality.