bluuebunny/crossref_metadata_2025 huggingface dataset:
Liberating Community-based Research: Rescuing Gramsci’s Legacy of Organic Intellectuals
Authors: Sousa José Wellington
Published: December 2022

This article aims to provoke a discussion around conceiving community members as community-based research facilitators and leaders of their own process of change. It argues this is possible by rescuing Gramsci’s legacy of organic intellectuals that is present in community-based research literature, particularly under the participatory research rubric. However, this perspective has been overshadowed by a strong emphasis on community-based research (CBR) as a collaborative research approach rather than a people’s approach for knowledge production that leads to social transformation. Furthermore, such a view of community-based research is fruitful within an adult education and social movement learning framework. In a sense, social movements provide an environment that facilitates critical consciousness and the formation of organic intellectuals and in which communities and academics learn to better engage in partnership for community-led social change. In this context, CBR is still a collaborative approach, but one led primarily by organic intellectuals.
“How are we in the world”: Teaching, Writing and Radical Generosity
Authors: Caldwell Lynn , Leung Carrianne
Published: December 2022

In the following exchange, Lynn Caldwell (member of the Engaged Scholar Journal Advisory Board, professor of theological ethics at St. Andrew’s College and sessional lecturer in Educational Foundations, Women’s and Gender Studies, at the University of Saskatchewan), and Carrianne Leung, Assistant Professor in creative writing, at the University of Guelph and writer of fiction, discuss radical generosity in the context of teaching in the Fine Arts. They remind us of how as engaged scholars, we carefully nurture generosity of thought, relations, and sharing in our work. They take that ethic one step further to show how radical generosity in the classroom rewards us with a well-informed society, and community of educators, activists, and change-makers.
The Origin of Isnad in Orientalist Perspective: Critical Study of Michael Cook’s Thought
Authors: Ghifari Muhammad , Zakiyah Ulfah
Published: December 2022

This article review Michael Cook’s thoughts on the early history of the use of isnad. Michael Cook disagrees with the opinions of the hadith scholars who said that the system of isnad only exists in Islam and is not found in other religions. Michael Cook believes that Islam is not the only sole owner of the isnad system. Long before Islam came the system of isnad had been used by previous religions, that is, it had been used by Jews in transmitting Mishnah. Even Michael Cook concluded that Islam had plagiarized the Jewish isnad system. The Islamic isnad system is very closely related to the Jewish isnad system which both have similarities and similarities in many ways. Therefore, Michael Cook believes that the Islamic isnad is a plagiarism of the Jewish isnad system. In this paper, the author explores Cook’s idea which generates two problems, namely what and how are the fundamental ideas (main points) of Michael Cook related to the initial use of isnad? And the second, how is the methodological foundation of Jews in carrying out criticism of isnad? In this study, the authors used a type of qualitative research, or what is known as library research. By using two data sources, namely primary data and secondary data.
Analisis Makna Kawā’ib dalam Al-Qur’an (Kajian Semantik Toshihiko Izutsu)
Authors: Monica Salma , Dasuki Akhmad , Faridatunnisa Nor
Published: December 2022

The term kawā'ib is mentioned once in the Koran in surah al-Nabā 'verse 33. The term kawā'ib in al-Qur'an and the translation means plump girls. This "plump" translation gives the impression that the Koran uses a vulgar connotation. The purpose of this study is an effort to express the meaning of the term kawā'ib in the al-Qur'an with the semantic approach of Toshihiko Izutsu. This type of research includes library research. To obtain a more precise meaning, the data obtained were interpreted using descriptive analysis and analytic induction. The theory used is the semantics of Toshihiko Izutsu. The principle of Izutsu semantic analysis is to analyze the basic meaning, relational meaning, historical meaning, and weltanschauung. This study resulted in the conclusion that the basic meaning analysis, term kawā'ib in Arabic grammatical is taken from the root word "ka'b" which means something that rises or stands out. The term kawā'ib is the plural of the word "kā'ib" which means a virgin girl with plump breasts. Then the term kawā'ib has a relational meaning: synonyms and antonyms such as al-unṡā, al-nisā`, imra'ah, niswah, hūr, al-fatā, al-rijāl and al-dzakar. In the analysis of historical meaning, the term kawā'ib has the meaning of prominent breasts or plump and virgin breasts. And weltanschauung term "kawā'ib" is a figure of youth in each individual.
Dialektika Islam dan Budaya Lokal dalam Tradisi Batamat al-Qur’an Urang Banjar
Authors: Saputra Riza
Published: December 2022

Batamat al-Qur'an is one of several important rituals in the life of Urang Banjar. The Banjarese people commonly perceive Batamat al-Qur'an as a meaningful celebration for their generation, it shows a successful aspect of mastering the holy book al-Qur'an. However, some of the previous local values or pre-Islamic traditions still colorize the process of Batamat al-Qur'an. The previous local value is considered to have positive impacts in Batamat al-Qur’an tradition. The findings of this study, which used a qualitative-descriptive approach, show that the dialectic between the Islamic religion and local culture raises a new meaning and a new contribution form in the life of the Banjarese people. Although Batamat al-Qur'an is a ritual that emphasizes the personal responsibility of Muslims to their God, this tradition has become a ritual that concerns with social aspect wherein the community, residents, and families involve together in Batamat al-Qur'an process.
An Ethnographic Review on the Reception of Sangir Community in Solok Selatan to Giving Alms
Authors: Syafruddin Syafruddin , Hasan Nursalman
Published: December 2022

This article describes the date of the existence of an economic pillar in a community or ethnic group that is part of the culture in welfare. The economic pillars are zakat, infaq, and sadaqah (alms). In its development, it has its own existence and different practices, such as that of the Sangir community, which understands alms to be true, giving, and appreciating. Forms of practice such as; first, on normal days which can be seen from the number of weekly receipts of the Sangir mosque which reaches millions of rupiah, secondly on major Islamic holidays such as Ramadan and Eid al-Adha, and thirdly at certain moments such as the Malapeh tradition which is carried out during the hundred days and julo-julo custom at the time of walimah. The existence and persistence of this cannot be separated from the knowledge possessed by the Sangir community, as well as the role of religious and traditional leaders in cultural settings. The variety of alms receptions that have become part of the pattern of people's lives certainly has an influence, both on the environment and for the ethnic community itself.
Al-Qur’an sebagai Basis Aktivitas Pendidikan: Kontribusi Tafsir Surat Luqman karya K.H. Abdulchalim Iskandar
Authors: Rohmana Jajang A
Published: December 2022

This article focuses on the issue of education in the Qur’anic commentary which is practiced into educational activities. The object of the study is a Sundanese book, Tafsir Surat Luqman (1955) by K.H. Abdulchalim Iskandar (1887-1962), a national hero from Majalengka. This Sundanese pegon book is a Qur’anic commentary of Sūrah Luqmān/31. Abdulchalim comments this sūrah and served the commentary as the basis for his educational activities from the colonial period to the Sukarno era. He founded some educational institutions such as Madjlisoel ‘Ilmi, Madrasah Jam’ijjat I’anat al-Muta’allimin, Madrasah Persjarikatan Oelama and Santi Asromo. Through Fairclough’s critical discourse analysis approach, this study confirms that Abdulchalim’s commentary of the Qur’an cannot be separated from his educational activities through the educational institution. His aim is how the indigenous people get a good education so that they have noble character and self-employed. This commentary of Surah Luqman is an example of how the verses of the Qur’an can be an inspiration in developing activities through the formation of educational institutions. It is a real practice of a national hero in practicing the Qur’anic verses bring into the reality.
Digitalisasi Hadis Ala Pusat Kajian Hadis (PKH): Distribusi, Ciri, dan Kontribusi dalam Kajian Hadis Indonesia
Authors: Suryadilaga Muhammad Alfatih , Qudsy Saifuddin Zuhri , Mustautina Inayatul
Published: December 2022

PKH is a pesantren which is famous for digitizing hadith, which has unique characteristics and designs that make it different from other pesantren. By using interpretative approach, this study showed that through variety of hadith, creativity can be enjoyed by the wider community. At least through the PKH’s url that not only gives the hadith emphasis but also general science, digital products that can be enjoyed as well as highly enlightening videos from various religious teachers who are highly trusted both from within and outside the country. Students who conduct training at PKH are also able to make applications through Android, namely thematic design and others such as pdf books which can be enjoyed in general. This phenomenon is a natural phenomenon in the technological era and they are hadith experts capable of displaying traditions to be readable in society at large. Student works can be blessed at the playstore on the cellphone with the PKH keyword or Hadith Study Center.
Cities and water: A fluvial and environmental analysis of Espinharas River in Patos city, Paraíba State
Authors: Silva Emmanoel Marques da , Carvalho Gabriel Lincoln Lopes , Silva Paulo Roberto de Oliveira , Silveira José Augusto Ribeiro da , Canova César Renato
Published: December 2022

The urbanization process over the last 70 years has provided cities with a distance from their relationship with the natural elements that comprise their surroundings and urban formation. Highlights include urban rivers that have mainly been deteriorated and forgotten by the population. Rivers have always been linked to the history and development of cities, but this relationship has led to conflicts over the years, starting a process of degradation that has culminated in deteriorating the relationship between rivers and cities. Based on this, the present work aims to analyze the fluvial and environmental conditions of a stretch of the Espinharas River in Patos city, Paraíba State, pointing out its weaknesses and potential. Based on the results obtained, a framework is proposed with guidelines capable of establishing this connection between the urban and natural environment, based on a tripod formed by the integration of the river with the city, recovery of its waters, and raising the population´s awareness of the importance from the river to the local quality of life. The research uses the hypothetical-deductive method, and its methodological steps are performed in three phases: the first is the literature review; the second, diagnosing the stretch of the river under analysis; and the last step addresses the construction of the framework of the guidelines. Finally, an understanding of the current situation of the stretch of the Espinharas River under analysis and the hypothetical effects of applying all selected guidelines is obtained, thus contributing to the qualification of relationship between the river and cities.
Systematic Review of Literature Applied to the Jesuit Landscape of the Municipality of Uruguaiana, RS
Authors: Morari Mariana Nicorena , Weiss Raquel , Pippi Luis Guilherme Aita
Published: December 2022

The Jesuit missions were of fundamental importance during the colonization period, with the proposal to catechize and protect the local indigenous from the slavery imposed by the Bandeirantes. The Jesuit priests developed a system of reductions, villages that had urban and rural structures, to self-support, helping each other in times of need. The Yapeyú Smelter, located on land now belonging to Argentina, would have been the most populous of the reductions and had the largest Jesuit cattle ranch, located on the opposite bank of the Uruguay River, in what is now Brazilian territory, the municipality of Uruguaiana/RS. Through the structure of their ranch, the Jesuits created their own landscape, which possibly would have influenced the formation of the local identity, with cattle raising still being the main economic base of the municipality. The article aimed to understand the state of art referring to scientific research on the Jesuit landscape in Uruguaiana or even in Rio Grande do Sul. For this, the systematic literature review method was used, which, through protocols for the development of the research, gathered materials that were grouped and evaluated, through bibliometric analysis.
High dose Levothyroxine in combination with transcranial magnetic stimulation for the treatment of severe resistant subthreshold rapid cycling bipolar disorder; A case report
Authors: Andy Zamar , Ashma Mohamed , Christos Kouimtsidis
Published: December 2022

Bipolar Disorder (BD) is a common psychiatric condition. There is an overall agreement across treatment guidelines of BD type I and BD type II however, there is far less certainty regarding the treatment of subthreshold presentations including Rapid Cycling Bipolar Disorder. We present a patient with treatment-resistant rapid cycling Bipolar Disorder type I who deteriorated on Ketamine treatment but reached full remission with repetitive Transcranial magnetic stimulation, High Dose Levothyroxine, Lurasidone and Lithium Carbonate. This case highlights the previously demonstrated safety and effectiveness of the combined protocol of High Dose Levothyroxine and Transcranial Magnetic Stimulation for this population.
Schistosome DNA Isolation and Colorimetric LAMP protocol for the detection of Schistosomiasis v1
Authors: Owusu-Frimpong Isaac
Published: December 2022

Schistosomiasis keeps devastating the world despite many measures put in place by control programs. Molecular diagnostics has played a significant role in the detection and monitoring of the treatment of the disease. Loop-medicated isothermal amplification has been developed with increased sensitivity and specificity to help the diagnosis of schistosomiasis. This protocol aids the successful isolation of schistosome DNA from urine and stool using Quick-DNA Miniprep kits (ZymoResearch, USA) with slight modification. Progressively, specific-specific Schisto-LAMP assay has been developed from the cytochrome c oxidase subunit 1 (COX1) gene of the schistosome mitochondrial genome. In addition, to effectively detect successful amplification, a laboratory-based colorimetric buffer which is pH dependent, was used. The neutral red dye changes from pale yellow to pink when positive and to a deep yellow color if negative. This protocol spells out the performance of two LAMP assays to detect S. haematobium and S. mansoni in urine and stool, respectively.
Aureococcus anophagefferens Virus (AaV)/Floreovirus quantuckensis viral particle count by SYBR Green staining and flow cytometry (CytoFLEX S Flow Cytometer Beckman Coulter) v1
Authors: E. Chase Emily
Published: December 2022

A method for obtaining viral particle counts of Aureococcus anophagefferens virus (AaV)/Floreovirus quantuckensis on a Beckman Coulter CytoFLEX S Flow Cytometry System (CytExpert software) using SYBR gold staining. Adapted from a protocol originally produced by Dr. Samantha Coy for PBCV-1, which was derived from Brussaard 2004; and *Brussaard et al. 2010. Brussaard CP. Optimization of procedures for counting viruses by flow cytometry. Appl Environ Microbiol. 2004 Mar;70(3):1506-13. doi: 10.1128/AEM.70.3.1506-1513.2004. PMID: 15006772; PMCID: PMC368280. Brussaard, C. P. D., J. P. Payet, C. Winter, and M. G. Weinbauer. 2010. Chapter 11: Quantification of aquatic viruses by flow cytometry. Manual of Aquatic Viral Ecology. Waco, TX:American Society of Limnology and Oceanography. doi:10.4319/mave.2010.978-0-9845591-0-7 *includes a published protocols.io: dx.doi.org/10.17504/protocols.io.dpj5km
The Incipient Formation of the Internal Dynamics of a Uniformly Moving Polaron in a Polynucleotide Chain Subjected To a Constant Electric Field
Authors: Korshunova A.N. , Lakhno V.D.
Published: December 2022

In this paper we consider the incipient formation of the internal dynamics of a uniformly moving polaron in a polynucleotide chain subjected to a constant electric field. The calculations performed show that Bloch oscillations arising in the course of the polaron oscillatory motion along the chain do not completely disappear when the polaron's motion along the chain becomes uniform. When the polaron moves uniformly along the chain, Bloch oscillations are also observed, although in a slightly different form. It is shown that the shape of the electron density distribution in a polaron during its stationary motion in a constant electric field takes an explicit structure. In this case, such characteristics of Bloch oscillations as the period of Bloch oscillations and the maximum Bloch amplitude demonstrate low-density components of the polaron.
Comparative Dynamics Analysis of Simple Mathematical Models of the Plankton Communities Considering Various Types of Response Function
Authors: Neverova G.P. , Zhdanova O.L.
Published: December 2022

The paper proposes a two-component discrete-time model of the plankton community, taking into account features of the development and interaction of phytoplankton and zooplankton. To describe the interaction between these species and to compare the system dynamics, we use the following set of response functions: type II and III Holling function and the Arditi–Ginzburg response function, each of which describes trophic interactions between phytoplankton and zooplankton. An analytical and numerical study of the model proposed is made. The analysis shows that the variation of trophic functions does not change the dynamic behavior of the model fundamentally. The stability loss of nontrivial fixed point corresponding to the coexistence of phytoplankton and zooplankton can occur through a cascade of period-doubling bifurcations and according to the Neimark–Saker scenario, which allows us to observe the appearance of long-period oscillations representing the alternation of peaks and reduction in the number of species as a result of the predator-prey interaction. As well, the model has multistability areas, where a variation in initial conditions with the unchanged values of all model parameters can result in a shift of the current dynamic mode. Each of the models is shown to demonstrate conditional coexistence when a variation of the current community structure can lead to the extinction of the entire community or its part. Considering the characteristics of the species composition, the model with the type II Holling function seems a more suitable for describing the dynamics of the plankton community. Such a system is consistent with the idea that phytoplankton is a fast variable and predator dynamics is slow; thus, long-period fluctuations occur at high phytoplankton growth rates and low zooplankton ones. The model with the Arditi–Ginzburg functional response demonstrates quasi-periodic fluctuations in a narrow parametric aria with a high predator growth rate and low prey growth rate. The quasi-periodic dynamics regions in the model with the Holling type III functional response correspond to the conception of fast and slow variables, however in this case, the stability of the system increases, and the Neimark-Sacker bifurcation occurs even at a higher growth rate of zooplankton.
Protein content in the above-ground parts of some wild-growing legume species of the Far East and Eastern Siberia
Authors:   N.I. Vavilov All-Russian Institute of Plant Genetic Resources, Burlyaeva M.O. , Solovyeva A.E. ,   N.I. Vavilov All-Russian Institute of Plant Genetic Resources, Sabitov Andrei Sh. ,   N.I. Vavilov All-Russian Institute of Plant Genetic Resources, Chebukin Pavel A. ,   Primorsky Fruit and Berry Experimental Station – a branch of Federal State Budgetary Scientific Institution “Federal Scientific Center of Agricultural Biotechnology of the Far East named after A.K. Chaika”, Perchuk I.N. ,   N.I. Vavilov All-Russian Institute of Plant Genetic Resources
Published: December 2022

The article presents data on the protein content in the above-ground parts of plants of 86 samples of 16 wild species of the legume family growing in natural habitats in the Far East and Eastern Siberia. The studied species were Lathyrus davidii, L. humilis, L. japonicus, L. komarovii, L. palustris, L. pilosus, L. pratensis, L. quinquenervius, Thermopsis lupinoides, Vicia amoena, V. baicalensis, V. ohwiana, V. pseudorobus, V. subrotunda, V. unijuga, V. venosa. As a result, a great diversity was revealed in terms of protein content in plants. The variability of this character reliably depended both on the belonging of the sample to a particular taxon and on its origin. The best protein content (> 20%) were found in the species: T. lupinoides, V. amoena, V. venosa and L. davidii and in populations – V. pseudorobus from China (> 26%), L. japonicus from Popov island and Khasansky district (> 25%), V. baicalensis from Irkutsk region (> 20%), L. pilosus from the Kamchatka Peninsula (20%).
New plants species for the Botanical Garden Garden-Institute FEB RAS and the Muravyev-Amursky Peninsula
Authors:   Botanical Garden-Institute FEB RAS, Nesterova Svetlana V.
Published: December 2022

Thirty-eight new species of vascular plants from 25 genera, 20 families were discovered on the forest territory of the Botanical Garden-Institute FEB RAS. The plants checklist includes seventeen new species that were not indicated on the Muravyev-Amursky Peninsula. Seven new genera for the botanical garden natural flora were identified. Among them, two genera are new for the Muravyev-Amursky Peninsula flora (Achudemia, Spuriopimpinella).
Biomorphological characteristics of weeds in Askizsky District (Republic of Khakasiya)
Authors:   Far Eastern Federal University, Sunchugasheva Larissa S. , Kalinkina Valentina A. ,   Botanical Garden-Institute FEB RAS
Published: December 2022

Biomorphological analysis of weed species of the flora of the Askizsky District are given. Using different approaches, the life forms of 103 species were characterized and the prevalence among weed species of taproot plants with an elongated erect type of shoot was revealed.
Lichenobiota of the Kytalyk National Park (Allaikhovsky District, Yakutia)
Authors:   St. Petersburg State University, Evdokimov G.S. , Konoreva Lyudmila A. ,   Botanical Garden-Institute FEB RAS,   Avrorin Polar-Alpine Botanical Garden-Institute KSC RAS,   Komarov Botanical Institute RAS, Chesnokov Sergei V. ,   Botanical Garden-Institute FEB RAS,   Komarov Botanical Institute RAS, Troeva Elena I. ,   Institute for Biological Problems of Cryolithozone SB RAS
Published: December 2022

The lichen biota of the Kytalyk National Park was studied for the first time ever. In total, 136 species of lichens and 1 lichenicolous fungus Sclerococcum deminutum were identified, among which 17 species were newly recorded for the Republic of Sakha (Yakutia). The data on new species distribution in the neighboring regions as well as in the studied area are given.
The current state of the collection of the genus Syringa in the Botanical Garden-Institute FEB RAS (Vladivostok): history of creation, taxonomic composition
Authors:   Botanical Garden-Institute FEB RAS, Pshennikova Lyudmila M. , Kolodin M.P. ,   Far Eastern Federal University
Published: December 2022

The article presents the history of the creation of the collection of lilacs and its taxonomic composition in the Botanical Garden-Institute FEB RAS. The collection fund is represented by two subgenera: Ligustrina and Syringa. The subgenus Syringa includes lilacs from 4 sections. The collection currently has 119 species, forms and varieties. A detailed description of new varieties is given. The modern collection of lilacs is represented by sufficient taxonomic diversity for conducting scientific researches.
Aspiring to Dutchness: Media Literacy, Integration, and Communication with Eritrean Status Holders
Authors: Van Kommer Rosanne , Hermes Joke
Published: December 2022

Based on 13 interviews with Eritrean status holders and professionals in Amsterdam this article explores how paying attention to media skills and media literacies may help gain a better understanding of what matters in exchanges between professionals and legal refugees in the mandatory Dutch integration process. Media literacy needs to be decolonised in order to do so. Starting as an inquiry into how professionals and their clients have different ideas of what constitutes “inclusive communication,” analysis of the interviews provides insight into how there is a need to (a) renegotiate citizenship away from the equation of neoliberal values with good citizenship and recognising needs and ambitions outside a neoliberal framework, (b) rethink components of formal and informal communication, and (c) reconceptualise media literacies beyond Western-oriented definitions. We propose that professionals and status holders need to understand how and when they (can) trust media and sources; how what we might call “open-mindedness to the media literacy of others” is a dialogic performative skill that is linked to contexts of time and place. It requires self-reflective approach to integration, and the identities of being a professional and an Eritrean stakeholder. Co-designing such media literacy training will bring reflexivity rather than the more generic term “competence” within the heart of both media literacy and inclusive communication.
Inclusive Media Education in the Diverse Classroom: A Participatory Action Research in Germany
Authors: Bozdağ Çiğdem
Published: December 2022

Media literacy has become a key concept for understanding how different citizens develop the capacity to participate in the mediatized society. One key question here is how media literacy education can support people of diverse backgrounds to have equal chances of benefiting from the media. Furthermore, as many schools are characterized by superdiversity, especially in bigger cities (Crul et al., 2013), there is also a need for research on media education and diversity. This article presents the findings of the research project INCLUDED, a participatory action research about media education in a secondary school in Germany. The project aims to analyse the everyday media use of young people with diverse cultural backgrounds living in a socio-economically disadvantaged neighbourhood and co-develop teaching modules on media literacy education integrating an intercultural perspective. The fieldwork of the project (January 2020–April 2021) included participatory observations (online and offline), teacher interviews, and focus groups with the students (13–15 years). The article will particularly focus on one teaching module that focused on TikTok and Instagram influencers. The students’ presentations in the classroom demonstrated how the diverse cultural backgrounds of the students also shaped the content that they consumed on social media. Analysing this teaching module as an example, this article discusses the benefits and challenges of designing a more inclusive and participatory approach to media education in the context of culturally diverse schools as an alternative to culture-blindness and over-emphasis of cultural differences.
Commentary
Authors: Годков И. М.
Published: December 2022

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Experience in the use of dendritic vaccines in the treatment of patients with recurrent gliomas
Authors: Rykov M. Yu. , Dolgopolov I. S.
Published: December 2022

Purpose of the study. To substantiate the expediency of cellular immunotherapy in the treatment of patients with relapses of high-grade gliomas and evaluate the safety of injecting allogeneic cells directly into the cerebrospinal fluid.

Materials and methods. Our study included 5 patients, median age 7,6 years (2–16). Three patients had anaplastic astrocytoma (AA) (1st recurrence – 1 patient, 2nd recurrence – 2 patients), 1 patient had glioblastoma multiforme (GBM) (3rd recurrence) and 1 had diffuse brainstem glioma (BSG). The median time to the first relapse was 12 months (4 to 16), to the second one was 5 months (1 to 8). The protocol of immunotherapy included combined administration of autologous dendritic cell-based vaccine (DV) and repeated intrathecal/intraventricular injections of donor allogenic immunocompetent cells (alloIC) for at least 2 years.

Results. Two of 3 patients with AA experienced a progression-free interval of 67 and 71 months One patient with 3rd GBM relapse is alive without any therapy 13.3 years after immunotherapy start. The median time of follow-up was 67 months with the 2‑years overall survival was 58 %. Two patients died from disease progression within 6 and 7 months from the start of immunotherapy. Over the period of treatment the patients received a median of 20 (8 to 60) alloIC injections and 18 (8 to 44) DV administrations. No serious side-effect was observed.

Conclusion. Immunotherapy could be an attractive option for treating patients with high-grade malignant gliomas irresponsible to conventional therapy and is worthy of further investigation.
Investigation of the antioxidant status and the number of double-stranded DNA breaks in models of brain tumor lesion by metastases of non-small cell lung cancer in vivo
Authors: Zaikina E. V. , Alliluev I. A. , Lazutin Yu. N. , Przhedetskiy Yu. V. , Shatova Yu. S. , Engibaryan M. A. , Komarova E. F. , Kharagezov D. A. , Galina A. V. , Kiblitskaya A. A. , Mindar M. V. , Kurbanova L. Z.
Published: December 2022

Purpose of the study. Evaluation of the antioxidant status and DNA damage in tissues of subcutaneous xenografts of non-small cell lung cancer and in peritumoral tissues created using the A549 and H1299 cell cultures.

Materials and methods. The study included 35 intact male Balb/c Nude immunodeficient mice. Cell lines A549 and H1299 were used as transplantable tumor biomaterial. A CDX model was created in accordance with the protocol for supratentorial injections (Ozawa T., James C. D., 2010) adapted for this experiment. Growth rates were controlled and intracranial xenografts were visualized using a high-resolution micro-CT system. The activity of catalase and superoxide dismutase was determined with non-denaturing electrophoresis in 8 % and 12 % polyacrylamide gel. The concentrations of sulfhydryl groups were determined according to Ellman. The DNA damage in lymphocytes was determined by the comet assay.

Results. The experiment resulted in the creation of models of brain tumors characterized by intracranial growth pattern in 100 %. The activity of catalase in the studied lysates of intracranial xenografts, peritumoral tissue and healthy tissues of tumor-bearing animals in all experimental groups increased statistically significantly relative to the healthy tissue of intact animals, and the greatest differences from the control were recorded in the group of animals with implanted H1299 culture at a concentration of 1 × 106 . Superoxide dismutase activity in the studied lysates of intracranial xenografts and peritumoral tissues statistically significantly increased compared to the control sample in all experimental groups. The highest increase in the SOD activity was observed in the tissues of intracranial xenografts with the highest tumor load, which amounted to 28.8 % and 32.9 % of the changes relative to the control sample. A statistically significant increase in the concentration of SH-groups relative to the control sample in tumor tissue lysates was revealed in all experimental groups, and the highest concentration (36.2 ± 0.47) was observed in the group of experimental animals with the highest tumor load. Percentage change in tail moment (DNA damage indicator) in groups O1, O2, O3 and O4 increased statistically significantly compared to the control sample by 55.8 %, 111.8 %, 97.3 % and 170 %, respectively.

Conclusions. The observed increase in the activity of the antioxidant defense system, accumulation of oxidative modifications of proteins, and an increase in DNA double-strand breaks in the tissues of intracranial xenografts of non-small cell lung cancer in vivo suggest that the created models reflect processes similar to those in tumors of human non-small cell lung cancer.
Possibilities of regulating the reaction of tissues of the implantation area with pyrimidine preparations after prosthetic repair of the hernia ring in the experiment
Authors: Lukoyanychev E. E. , Izmailov S. G. , Evsyukov D. A. , Nikolskij V. O. , Mironov A. A. , Panyushkin A. V.
Published: December 2022

Purpose of the study. Study of the possibilities of pharmacological regulation of local and systemic inflammatory response, stimulation of reparative regeneration in prosthetic repair of abdominal wall hernias.

Materials and methods. The experiment was carried out on 92 rats of both sexes of a pure line, divided into 4 groups. Group I (control) received only 1 ml of 0.9 % sodium chloride solution. Group II – hydroxyethyldimethyldihydropyrimidine 21 mg/day. Group III – potassium orotate 10.5 mg/day. Group IV – methyluracil 14 mg/day. Under anesthesia a mesh implant 4 × 2 cm was placed in the layer between the hypodermis and the superficial fascia. Animals were withdrawn from the experiment on days 5 (n = 52) and 14 days (n = 40). The site of implantation for histomorphometric studies captured the dermis, hypodermis, implant layer, fascia, and muscle. The preparation and staining of the preparations were carried out with hematoxylin-eosin and by Mallory.

Results. 1. On the 5th day after the operation group II (hydroxyethyldimethyldihydropyrimidine) was characterized by pronounced neovasculogenesis (p = 0.002, U-test) and more active processes of formation and maturation of connective tissue (p = 0.024, U-test) with a low immune response to a foreign body (p = 0.044, U- test). III (potassium orotate) and IV groups (methyluracil) were characterized by a pronounced decrease in the inflammatory response with a simultaneous increase in tissue edema (p < 0.001, U-test), slowing down the formation and maturation of connective tissue (p = 0.016, U-test). 2. On the 14th day after the operation, group II (hydroxyethyldimethyldihydropyrimidine) was characterized an increase in the area of neovasculogenesis by 208.0 % (p < 0.001, U -criterion), a decrease in the volume of fluid accumulations by 63.4 % (p < 0.001, U-criterion), an increase in the processes of formation and maturation of connective tissue, mainly due to an increase in the number of fibrocytes by 333.3 % (p < 0.001, U-criterion). The parameters of the immune response to a foreign body had significant differences (p < 0.001, U-test).

Conclusion. The use of potassium orotate and methyluracil reduces the inflammatory response in the tissues of the implantation area, however, it is associated with the appearance of liquid components and with a decrease in the formation of connective tissue cells. The use of hydroxyethyldimethyldihydropyrimidine is devoid of the above disadvantages, it is characterized by the predominance of regeneration and neovasculogenesis processes, which allows it to be used as a pharmacological support drug for prosthetic hernioplasty.
Who Is This Godot? The Academy of Certified Archivists and Graduate Archival Education
Authors: Todd-Diaz Ashley , Poole Alex H.
Published: December 2022

Since the 1936 founding of the Society of American Archivists, the archival field has struggled with the challenges inhering in professionalization, namely the merits or demerits of institutional or individual accreditation or certification. In 1989, SAA helped establish the Academy of Certified Archivists (ACA), which confers individual certification by written examination. In 1993, ACA modified its bylaws to require graduate education to be eligible for the exam. But, although a relationship clearly exists between certification and education, scholars have not explored, much less profited from, the insights of archival educators. This qualitative case study uses semistructured interviews with thirty-three tenure-track or tenured faculty program directors from graduate archival programs across North America to understand how educators perceive and address certification. Findings reveal that educators are ambivalent about certification, its relationship to graduate education, and its vocational value. The authors discuss the implications of these findings and offer suggestions for research and practice.
A Survey on the Communication Protocols and Security in Cognitive Radio Networks
Authors: Meghanathan Natarajan
Published: December 2022

A cognitive radio (CR) is a radio that can change its transmission parameters based on the perceived availability of the spectrum bands in its operating environment. CRs support dynamic spectrum access and can facilitate a secondary unlicensed user to efficiently utilize the available underutilized spectrum allocated to the primary licensed users. A cognitive radio network (CRN) is composed of both the secondary users with CR-enabled radios and the primary users whose radios need not be CR-enabled. Most of the active research conducted in the area of CRNs has been so far focused on spectrum sensing, allocation and sharing. There is no comprehensive review paper available on the strategies for medium access control (MAC), routing and transport layer protocols, and the appropriate representative solutions for CRNs. In this paper, we provide an exhaustive analysis of the various techniques/mechanisms that have been proposed in the literature for communication protocols (at the MAC, routing and transport layers), in the context of a CRN, as well as discuss in detail several security attacks that could be launched on CRNs and the countermeasure solutions that have been proposed to avoid or mitigate them. This paper would serve as a good comprehensive review and analysis of the strategies for MAC, routing and transport protocols and security issues for CRNs as well as would lay a strong foundation for someone to further delve onto any particular aspect in greater depth.
Robust Sampling Clock Recovery Algorithm for Wideband Networking Waveform of SDR
Authors: Zeeshan Muhammad , Khan Shoab Ahmed
Published: December 2022

A novel technique for sampling clock recovery in a wideband networking waveform of a software defined radio is proposed. Sampling clock recovery is very important in wideband networking radio operation as it directly affects the Medium Access adaptive time slot switching rate. The proposed Sampling clock recovery algorithm consists of three stages. In the first stage, Sampling Clock Offset (SCO) is estimated at chip level. In the second stage, the SCO estimates are post-filtered to improve the tracking performance. We present a new post-filtering method namely Steady-State State-Space Recursive Least Squares with Adaptive Memory (S4RLSWAM). For the third stage of SCO compensation, a feedforward Lagrange interpolation based algorithm is proposed. Real-time hardware results have been presented to demonstrate the effectiveness of the proposed algorithms and architecture for systems requiring high data throughput. It is shown that both the proposed algorithms achieve better performance as compared to existing algorithms.
Evaluation MCDM Multi-disjoint Paths Selection Algorithms Using Fuzzy-Copeland Ranking Method
Authors: Naderi Hamid , Shahosseini Hadi , Jafari Amir
Published: December 2022

To increase the Internet's reliability and to have greater control over traffic transmission, reliable path selection is important and Multipath routing is promising technique that are used in the communication networks. Finding reliable end-end paths and backup can increase network performance. So, using proper decision metrics and algorithm should be used to paths and backup selection phase in these networks. For this goal, in this paper selecting a more reliable multi disjoint paths is addressed as a multi-criteria decision making (MCDM) problem and availability factor is defined and calculated based on network histories. For decision algorithm, a new fuzzy evaluation method is proposed to rank these multi disjoint paths selection algorithms and it is compared with bandwidth based, TOPSIS, FuzzyTOPSIS and AHP methods as candidate techniques to select more appropriate global disjoint paths in the IP/MPLS networks with packet loss, delay and availability parameters as decision making metrics. The proposed method combines fuzzy theory and Copeland method to evaluate the rank of each proposed method base on bandwidth, delay and new defined availability metric of selected end to end paths. Simulation results show that this method selects more reliable backup paths with better bandwidth in compared with others and can be used to path selection in IP/MPLS networks.
Lateral Pre-crash Sensing and Avoidance in Emotion Enabled Cognitive Agent based Vehicle-2-Vehicle Communication System
Authors: Riaz Faisal , Shah Syed Ismail , Raees Muhammad , Shafi Imran , Iqbal Arslan
Published: December 2022

A novel inter-vehicle communication system based on emotion enabled cognitive (EEC) agent has been anticipated as an intelligent solution to evade the road catastrophe due to hasty decisions by drivers. An input stimulus is processed in human brain using a short route and a long route during any emergency situation. The proposed EEC agent, mounted inside a vehicle, acts like a human brain and is stirred by short route information processing mechanism of human brain in fear condition. The results are acquired for the decisions made by the proposed approach through the EEC agent using short route and human drivers using long route during urgent situations. A pre crash sensing and avoidance algorithm has been proposed as well to mitigate the lateral or side by side collision using EEC agent.  Experimental findings reveal that by commencing emotions with cognition, and using formulated L-PCSA algorithm, lateral collisions chances can be sensed and avoided to secure the valued lives of passengers. It has been pragmatic that the new approach is very effectual and useful in shunning the lateral road collisions.
An Enhanced Entropy Approach to Detect and Prevent DDoS in Cloud Environment
Authors: Jeyanthi N , Iyengar N.Ch.S.N , Kumar P C Mogan , A Kannammal
Published: December 2022

Distributed Denial of Service (DDoS) attack launched in Cloud computing environment resulted in loss of sensitive information, Data corruption and even rarely lead to service shutdown. Entropy based DDoS mitigation approach analyzes the heuristic data and acts dynamically according to the traffic behavior to effectively segregate the characteristics of incoming traffic. Heuristic data helps in detecting the traffic condition to mitigate the flooding attack. Then, the traffic data is analyzed to distinguish legitimate and attack characteristics. An additional Trust mechanism has been deployed to differentiate legitimate and aggressive legitimate users. Hence, Goodput of Datacenter has been improved by detecting and mitigating the incoming traffic threats at each stage. Simulation results proved that the Enhanced Entropy approach behaves better at DDoS attack prone zones. Profit analysis also proved that the proposed mechanism is deployable at Datacenter for attack mitigation and resource protection which eventually results in beneficial service at slenderized revenue
A Secure Method for Authenticity Verification of Handwritten Signatures Through Digital Image Processing and Artificial Neural Networks
Authors: Franco Deivison Pinheiro , Barboza Felipe Dantas , Cardoso Nágila Magalhães
Published: December 2022

This paper aims to propose a method to do authenticity verification of handwritten signatures based on the use of digital image processing and artificial neural networks techniques through the backpropagation learning algorithm with 500 and 901 approaches, in order to optimize this verification process and act as a decision support tool, in an automated way. The results showed an average percentage error of 20% in the first and of 5.83% in the second, while the performance of a trained professional for that has an average error of 6.67%. Thus, we could observe the efficiency of the proposed method, as well as the difference and evolution of approaches through the relevance of the results.
Design and Implementation of ID Based MANET Autoconfiguration Protocol
Authors: Khalid Shahrukh , Mahboob Athar
Published: December 2022

Auto-configuration protocols are used for assignment of unique IP addresses to nodes in Mobile ad hoc networks. Without the assignment of unique IP addresses, service provisioning between the nodes is not possible. Such protocols use various heuristics to ensure the uniqueness in IP address assignment; such aspects increase the overall complexity in MANET system design. Moreover the overriding role of IP address as an ID in Application layer and Locator in routing space is a bottleneck in future wireless network (FWN) design. Contemporary FWN research is focusing on ID/Locator split concept designs. In this paper we propose an ID/Locator based architecture for MANETs which also solves               auto-configuration requirements for MANETs. Our proposed architecture is an adaptation from available ID/Locator split concepts for infrastructure oriented networks for usage in MANET context. The designed protocol uses identifiers for node identification, node discovery and traffic flow between end points. The protocol support provision for running contemporary IP oriented services. We have also verified various use cases of our proposed protocol through Linux based implementation.
Decoding of Block Codes by using Genetic Algorithms and Permutations Set
Authors: Nouh Said , Chana Idriss , Belkasmi Mostafa
Published: December 2022

Recently Genetic algorithms are successfully used for decoding some classes of error correcting codes. For decoding a linear block code C, these genetic algorithms computes a permutation p of the code generator matrix depending of the received word. Our main contribution in this paper is to choose the permutation p from the automorphism group of C. This choice allows reducing the complexity of re-encoding in the decoding steps when C is cyclic and also to generalize the proposed genetic decoding algorithm for binary nonlinear block codes like the Kerdock codes. In this paper, an efficient stop criterion is proposed and it reduces considerably the decoding complexity of our algorithm. The simulation results of the proposed decoder, over the AWGN channel, show that it reaches the error correcting performances of its competitors. The study of the complexity shows that the proposed decoder is less complex than its competitors that are based also on genetic algorithms.