bluuebunny/crossref_metadata_2025 huggingface dataset:
A Review on Key Innovation Challenges for Smart City Initiatives
Authors: José Rui , Rodrigues Helena
Published: January 2024

Smart city initiatives are being promoted across the world to address major urban challenges, and they all share a common belief in the transformative power of digital technologies. However, the pace of innovation in smart cities seems to be much slower than the rapid and profoundly disruptive transformations brought about by digital innovation in many other domains. To develop new insights about the main causes behind this relatively modest success, this study provides a Systematic Literature Review (SLR) on the connection between major smart city challenges and the essential properties of digital innovation. The review involved the qualitative analysis of 44 research papers reporting on smart city innovation practices and outcomes. The results characterize five major challenge categories for smart city innovation: Strategic vision; Organizational Capabilities and Agility; Technology Domestication; Ecosystem Development; and Transboundary Innovation. This study also explores the connections between these challenges and concrete digital innovation practices in smart city initiatives. The main conclusion is that current innovation practices in smart cities are not properly aligned with what the research literature commonly describes as core properties of digital innovation and that this might be a major cause behind the limited progress in smart city initiatives.
Modified Social Group Optimization to Solve the Problem of Economic Emission Dispatch with the Incorporation of Wind Power
Authors: Secui Dinu Calin , Hora Cristina , Bendea Codruta , Secui Monica Liana , Bendea Gabriel , Dan Florin Ciprian
Published: January 2024

Economic dispatch, emission dispatch, or their combination (EcD, EmD, EED) are essential issues in power systems optimization that focus on optimizing the efficient and sustainable use of energy resources to meet power demand. A new algorithm is proposed in this article to solve the dispatch problems with/without considering wind units. It is based on the Social Group Optimization (SGO) algorithm, but some features related to the selection and update of heuristics used to generate new solutions are changed. By applying the highly disruptive polynomial operator (HDP) and by generating sequences of random and chaotic numbers, the perturbation of the vectors composing the heuristics is achieved in our Modified Social Group Optimization (MSGO). Its effectiveness was investigated in 10-unit and 40-unit power systems, considering valve-point effects, transmission line losses, and inclusion of wind-based sources, implemented in four case studies. The results obtained for the 10-unit system indicate a very good MSGO performance, in terms of cost and emissions. The average cost reduction of MSGO compared to SGO is 368.1 $/h, 416.7 $/h, and 525.0 $/h for the 40-unit systems. The inclusion of wind units leads to 10% reduction in cost and 45% in emissions. Our modifications to MSGO lead to better convergence and higher-quality solutions than SGO or other competing algorithms.
Advancements and Applications of Life Cycle Assessment in Slope Treatment: A Comprehensive Review
Authors: Yao Yongsheng , Xu Peiyi , Li Jue , Hu Hengwu , Qi Qun
Published: January 2024

Life cycle assessment (LCA) plays an increasingly important role in environmental management, particularly in promoting energy and carbon-conscious practices across various disciplines. This review provides an overview of the latest innovations and potential benefits of integrating LCA into ecological slope treatment strategies. This study explores new developments in LCA methodology and its application to slope treatment, aiming to improve the integration of infrastructure development and environmental stewardship. Through an extensive review of over 120 peer-reviewed journal articles and a critical analysis of the intersection of LCA with slope treatment, this paper identifies innovative techniques that have the potential to significantly reduce the environmental impact of slope management. The review emphasizes advanced LCA practices that quantify and mitigate carbon emissions throughout the life cycle stages of slope treatments. Key findings demonstrate that LCA enhances the methodological rigor in assessing ecosystem services and impacts, and reveals new strategies that emphasize the importance of ecological considerations in infrastructure projects. Future research directions focus on refining LCA data acquisition and promoting a standardized knowledge base to support precision in ecological impact assessments. In conclusion, the adoption of LCA in slope treatment is imperative for aligning industry practices with global sustainability targets, emphasizing the importance of integrating uncertainty analysis and long-term impact assessments to bolster the credibility of LCA outcomes.
Scenario Simulation and Driving Force Analysis of Ecosystem Service Values Based on Land Use/Cover in the Tumen River Basin, China
Authors: Ding Richen , Li Yuchen , Zhao Chunzi , Chen Jingping , Zhu Weihong
Published: January 2024

Key ecological function areas play a crucial role in safeguarding and rehabilitating ecosystems and mitigating regional ecological degradation. Unraveling the interconnectedness between land use/cover (LULC) transformation and the ecosystem service value (ESV) in these regions is of profound importance for sustainable development. In this paper, the LULC response in the Tumen River Basin (TRB) to an assessment of ESV from 2000 to 2020 was explored. An advanced equivalent factor that incorporates both biomass and socioeconomic factors was used to evaluate the ESV of the TRB. Taking the potential impact of factors such as temperature (TEM), precipitation (PRE), normalized difference vegetation index (NDVI), digital elevation model (DEM), soil organic matter content (SOMC), and human activity intensity of land surface (HAILS) into account, the patch-generating land use simulation model (PLUS) was used to simulate and predict the spatial evolution of the ESV under different land resource management strategies in 2030. The results indicate an increasing trend in the total ESV in the study area from 2000 to 2020, with forested land accounting for nearly 94% of the total ESV for the TRB. HAILS, DEM, and NDVI were identified as the main factors affecting the spatial differentiation of ESV. A negative correlation (−0.65) was found between ESV and the landscape shape ndex (LSI), indicating that more irregularly shaped landscapes have a lower ESV. Positive correlations were observed between the Shannon’s Diversity Index (SHDI) (0.72) and the Aggregation Index (AI) (0.60), suggesting that more diverse and interconnected landscapes have a higher ESV. The PLUS simulation results provide valuable data-based support for achieving planning objectives under different land resource management strategies. Specifically, these findings can serve as a reference for the integrated planning of land resources and environmental protection, promoting the sustainable development of ecological functional areas along the northeast border of China.
Does the National Carbon Emissions Trading Market Promote Corporate Environmental Protection Investment? Evidence from China
Authors: Yang Xiao , Jia Wen , Wang Kedan , Peng Geng
Published: January 2024

China launched the National Carbon Emissions Trading Market (NCETM) in July 2021, heralding the first nationwide implementation of carbon emissions trading since the 2011 pilot scheme in China. The NCETM serves as a vital policy instrument that employs market mechanisms to regulate and mitigate greenhouse gas emissions. Thus, this study aims to examine how the NCETM in China, as an environmental regulatory policy, impacts environmental protection investment (EPI) made by enterprises. Specifically, the research seeks to address three key questions: (1) Does the NCETM have an impact on corporate EPI? (2) What are the mechanisms underlying the effect of the NCETM on corporate EPI? (3) Additionally, does the impact of the NCETM on corporate EPI vary with the location of the firms? By utilizing financial data from listed firms from 2018 to 2022 and employing the difference-in-differences (DID) model, the empirical results suggest that: (1) NCETM significantly stimulates the increase in EPI by firms. (2) The NCETM promotes environmental investment by inducing higher R&D expenditures. (3) The effects of NCETM on firms’ EPI vary across regions, with the policy only being effective for firms in non-pilot regions that did not engage in the carbon emissions trading market prior to NCETM. This study provides empirical evidence for the microeconomic effects of the NCETM and a useful reference for the implementation of carbon emissions trading policies.
Impact and Mechanisms of Digital Inclusive Finance in Relation to Farmland Transfer: Evidence from China
Authors: Xu Ziqin , Niu Hui , Wei Yuxuan , Wu Yiping , Yu Yang
Published: January 2024

Land use efficiency is primarily limited by the fragmentation of land management. China’s fragmented farmland poses a significant threat to the country’s food security and rural revitalization. Therefore, promoting land transfer to establish large-scale operations is a significant solution. With digital technology’s advancements, digital inclusive finance (DIF) has permeated rural regions to provide financial assistance for farmers’ livelihood and rural development. However, it remains unclear if and how DIF can incentivize land transfer. Therefore, this paper aims to establish an econometric model to analyze the impact of digital inclusive finance on land transfer. Additionally, a chain mediation effect model is established to analyze how DIF affects land transfer through an exploration of the mechanisms of farmers’ livelihood capital and the use of digital information. Therefore, the findings from the analysis of data from 3165 farmers demonstrate that DIF has the potential to notably facilitate land transfer and work through the chain mediation channel. Moreover, the impact of DIF on land transfer is even more pronounced in economically developed regions. Consequently, this paper’s results hold the potential to inform policy making by offering insight into three viable paths—digital inclusive financial support, livelihood capital, and digital information—as means to promote land transfer.
Geospatial Tools and Remote Sensing Strategies for Timely Humanitarian Response: A Case Study on Drought Monitoring in Eswatini
Authors: Munyaka Jean-Claude Baraka , Chenal Jérôme , Mabaso Sizwe , Tfwala Samkele Sikhulile , Mandal Anil Kumar
Published: January 2024

This article explores the escalating impact of natural disasters, particularly droughts, in the Southern African Development Community (SADC), with a specific focus on Eswatini. Over the last century, approximately 63 million people in SADC countries have been affected by droughts, leading to challenges in agriculture, livestock losses, and severe food and water shortages. Despite being the smallest SADC nation, the Kingdom of Eswatini faces disproportionate consequences due to its susceptibility to climate variability, particularly drought. The inadequacy and unreliability of rainfall have resulted in a drastic reduction in food production, with maize, a staple crop, experiencing a 70% decline. This adverse trend, spanning three decades, has heightened the vulnerability of farmers to climatic shocks, hindering sustainable agricultural development and impeding poverty alleviation efforts. To address the growing threat of drought in the kingdom, a comprehensive approach is imperative, involving coordinated plans and the development of swift humanitarian relief strategies. This study utilized remote sensing technologies to monitor drought and assess its repercussions, evaluating the impact on agricultural production. Additionally, geospatial tools, including Open Route Service (ORS) and Near Neighbor Analysis algorithms, were employed to optimize humanitarian supply chain logistics. Results from the analysis, including Vegetation Health Index (VHI) fluctuations and drought severity mapping, reveal that 1990 was the year the kingdom was most severely hit by drought. This study also found that smallholder farmers practicing rainfed agriculture in vulnerable regions, such as the lower Middleveld and western Lowveld, suffered the severe socioeconomic consequences of agricultural drought, including income loss, food insecurity, and migration patterns. Through this integrated approach, decision makers can engage in targeted interventions, focusing on farming areas needing irrigation infrastructures or populated areas requiring a coordinated humanitarian response amidst climate variability.
A Framework for Assessing Hydrochars from Hydrothermal Carbonisation of Agrowaste with the Use of MCDA: Application with the Hierarchical SMAA-PROMETHEE Method
Authors: Isigonis Panagiotis , Corrente Salvatore , Vakalis Stergios
Published: January 2024

Large amounts of hydrochar have been produced during the last decade by various hydrothermal carbonisation (HTC) processes. While the products of HTC seem to have widespread acceptance as valuable and efficient materials with advantages in their energy and environmental applications, which include soil improvement, heavy metal recovery, and many more, a comprehensive framework for the assessment of the different hydrochars based on their characteristics is missing. In this study, a framework for the assessment of hydrochars is proposed with the utilisation of Multi-Criteria Decision-Aiding (MCDA) methodologies. A hierarchical structure of independent criteria is established on a comprehensive level including three lines of evidence (LoE), i.e., Environmental, Economic, and Social LoE, which further include the assessment criteria. Hierarchical-SMAA-PROMETHEE is proposed as the most suitable MCDA methodology to be applied for assessing hydrochars based on the proposed framework. A case study is performed to demonstrate the utility of the framework and the advantages it offers to analysts and decision-makers. Hierarchical-SMAA-PROMETHEE is a non-compensatory method that enables exploring the decision problem on more than one level (comprehensive vs. LoE) and includes robust recommendations on the preference model and the elicitation of weights.
Photocatalytic Removal of Metronidazole Antibiotics from Water Using Novel Ag-N-SnO2 Nanohybrid Material
Authors: Shuvo Md. Shahriar Hossain , Putul Rupna Akther , Hossain Khandker Saadat , Masum Shah Md. , Molla Md. Ashraful Islam
Published: January 2024

In this study, we employed a straightforward synthetic approach using the sol-gel method to fabricate a novel photocatalyst, Ag and N co-doped SnO2 (Ag-N-SnO2). The synthesized photocatalysts underwent characterization through various techniques including XRD, FTIR, FESEM-EDS, TEM, UV-vis DRS, BET, and XPS. The UV-vis DRS results confirmed a reduction in the bandgap energy of Ag-N-SnO2, leading to enhanced absorption of visible light. Additionally, TEM data demonstrated a smaller particle size for Ag-N-SnO2, and BET analysis revealed a significant increase in surface area compared to SnO2.The efficiency of the Ag-N-SnO2 photocatalyst in degrading metronidazole (MNZ) under natural sunlight surpassed that of SnO2. Under optimal conditions (Ag-N-SnO2 concentration of 0.4 g/L, MNZ concentration of 10 mg/L, pH 9, and 120 min of operation), the highest MNZ photocatalytic removal reached 97.03%. The reaction kinetics followed pseudo-first-order kinetics with a rate constant of 0.026 min−1. Investigation into the mineralization of MNZ indicated a substantial decrease in total organic carbon (TOC) values, reaching around 56% in 3 h of sunlight exposure. To elucidate the photocatalytic degradation mechanism of MNZ with Ag-N-SnO2, a scavenger test was employed which revealed the dominant role of •O2–. The results demonstrated the reusability of Ag-N-SnO2 for up to four cycles, highlighting its cost-effectiveness and environmental friendliness as a photocatalyst.
Rehabilitation of Urban Beaches on the Mediterranean Coast in Valencia (Spain) Observed by Remote Sensing
Authors: Molner Juan Víctor , Pérez-González Rebeca , Soria Juan M.
Published: January 2024

Beaches, as ecosystems of high ecosocial and biodiversity importance, are threatened by human activities such as city development and port construction. This study used satellite imagery (Landsat 5, Landsat 8, and Sentinel-2) to detect a significant reduction of 70% in the beach areas of El Saler and La Garrofera (Valencia, Spain) from 170 ha in the 1990s to 43 ha in the year 2022. This process has occurred in parallel with the successive expansion of the Port of Valencia, a modifying agent of marine sedimentation in the region. In addition, encouraging results have been observed in the rehabilitation efforts in different periods. The latest work in the autumn of 2023 has improved the beach area to 112 ha. In this context, remote sensing emerges as an essential tool to monitor these ecosystems, which are important for both human welfare and biodiversity conservation, as well as to allow for monitoring during ecological restoration.
Elucidating the Molecular Determinants of the Binding Modes of a Third-Generation HIV-1 Integrase Strand Transfer Inhibitor: The Importance of Side Chain and Solvent Reorganization
Authors: Sun Qinfang , Biswas Avik , Lyumkis Dmitry , Levy Ronald , Deng Nanjie
Published: January 2024

The first- and second-generation clinically used HIV-1 integrase (IN) strand transfer inhibitors (INSTIs) are key components of antiretroviral therapy (ART), which work by blocking the integration step in the HIV-1 replication cycle that is catalyzed by a nucleoprotein assembly called an intasome. However, resistance to even the latest clinically used INSTIs is beginning to emerge. Developmental third-generation INSTIs, based on naphthyridine scaffolds, are promising candidates to combat drug-resistant viral variants. Among these novel INSTIs, compound 4f exhibits two distinct conformations when binding with intasomes from HIV-1 and the closely related prototype foamy virus (PFV) despite the high structural similarity of their INSTI binding pockets. The molecular mechanism and the key active site residues responsible for these differing binding modes in closely related intasomes remain elusive. To unravel the molecular determinants governing the two distinct binding modes, we applied a novel molecular dynamics-based free energy method that utilizes alchemical pathways to overcome the sampling challenges associated with transitioning between the two bound conformations of ligand 4f within the crowded environments of the INSTI binding pockets in these intasomes. The calculated conformational free energies successfully recapitulate the experimentally observed binding mode preferences in the two viral intasomes. Analysis of the simulated structures suggests that the observed binding mode preferences are caused by amino acid residue differences in both the front and the central catalytic sub-pocket of the INSTI binding site in HIV-1 and PFV. Additional free energy calculations on mutants of HIV-1 and PFV revealed that while both sub-pockets contribute to binding mode selection, the central sub-pocket plays a more important role. These results highlight the importance of both side chain and solvent reorganization, as well as the conformational entropy in determining the ligand binding mode, and will help inform the development of more effective INSTIs for combatting drug-resistant viral variants.
Invasive Bacterial Infections of the Musculoskeletal and Central Nervous System during Pig Rearing: Detection Frequencies of Different Pathogens and Specific Streptococcus suis Genotypes
Authors: Bornemann Ninette Natascha , Mayer Leonie , Lacouture Sonia , Gottschalk Marcelo , Baums Christoph Georg , Strutzberg-Minder Katrin
Published: January 2024

Locomotor and central nervous system disorders occur during pig rearing, but there is no systematic recording of the different causative agents in Germany. Joint and meningeal swabs, kidneys, lungs, and eight different lymph nodes per pig were cultured, and isolated pathogens were identified using polymerase chain reactions (PCRs). The cps and pathotype of Streptococcus suis (S. suis) isolates were determined using multiplex-PCR. S. suis was the most important pathogen in the infected joints (70.8%) and meningeal swabs (85.4%) and was most frequently detected in both sites in suckling and weaning piglets. To elucidate the possible portal of entry of S. suis, eight different lymph nodes from 201 pigs were examined in a prospective study. S. suis was detected in all examined lymph nodes (n = 1569), including the mesenteric lymph nodes (15.8%; n = 121/765), with cps 9 (37.2%; n = 147) and cps 2 (24.3%; n = 96) being the most dominating cps types. In piglets with a systemic S. suis infection, different lymph nodes are frequently infected with the invasive S. suis strain, which does not help clarify the portal of entry for S. suis.
Exploring the Current Status and Future Potential of Robot, Artificial Intelligence, and Service Automation in the Indonesian Tourism Industry
Authors: Asmoro Agung Yoga , Butler Gareth , Szili Gerti
Published: January 2024

This paper examines the current state and potential future applications of robots, artificial intelligence, and service automation (RAISA) in the hospitality, travel, and tourism industry, with a focus on Indonesia. The study utilizes a comprehensive review of literature and empirical data, including case studies, industry reports, and scholarly articles, to gather relevant information. The findings reveal that while the implementation of RAISA in the Indonesian tourism industry is still in its introductory stage, advancements in RAISA technology and decreasing costs make it increasingly viable for substituting human labor in repetitive and high-risk tasks. However, it is important to consider that not all service processes are suitable for automation or delegation to robots. The decision to automate or retain human labor depends on factors such as economic efficiency, customer satisfaction, company competitiveness, and other internal and external considerations. This research contributes to the existing literature by addressing the specific context of Indonesia and providing insights into the current state and potential future applications of RAISA in the hospitality, travel, and tourism industry. It highlights the scarcity of research in this area and emphasizes the need for further investigation, particularly in areas such as the economic rationale of service automation, the readiness of businesses to adopt RAISA, stakeholder attitudes towards service robots, the impact of RAISA on service quality and company competitiveness, and the ethical considerations associated with its implementation. The findings of this study offer valuable insights for industry practitioners, policymakers, and researchers aiming to understand the benefits, challenges, and implications of integrating RAISA in the Indonesian tourism industry.
The Experiences of Graduates Who Transferred to a Bachelor of Science in Nursing Program at a College
Authors:   Korean Society of Nursing Research, Kim Ji Mee , Park Keum Sook , Kim Young Hee , Jeong Young Ju
Published: January 2024

Purpose : The purpose of this study was to understand and describe the experiences of graduates of the bachelor’s transfer system with a college nursing program. Methods : Focus group interviews were conducted with 13 participants who had graduated from the bachelor’s degree transfer program with the college nursing department. Interview were conducted in two groups, and were recorded and transcribed after obtaining consent from the participants, and the collected data were analyzed with a qualitative content analysis. Results : Fourteen categories emerged from the four main themes of (1) choice motivation: a big chance in my life, an attractive job recognized by self and others; (2) thoughts on nursing: patient care in clinical settings, various roles, jobs that require knowledge in the humanities and in-depth knowledge; (3-1) major courses (curriculum): inconvenient to complete general education courses, burdensome to complete major courses, difficulty getting into relationships and adapting to school life; (3-2) major courses (school and departmental support): unstable academic management, inadequate transfer student scholarship system, difficulty in sharing pre-information about academics; and (4) opinions on system improvement: operation of an independent undergraduate transfer system and recognizing the need for systematic student guidance. Conclusion : Findings of this study, based on the experiences of bachelor’s degree transfer students with a college nursing program, indicate a need to explore various educational strategies and directions for the efficient operation of such transfer programs.
The Effects of Maternal Nursing Practice Using Case-Based Extended Reality (XR) Content Programs
Authors:   Korean Society of Nursing Research, Kwak Keun Hye , Park Sun Jung
Published: January 2024

Purpose : The purpose of this study is to assess the effectiveness of using case-based Extended Reality content programs developed for nursing college students in maternal nursing practice. Methods : This was a quasi-experimental study that used two groups and a pretest-posttest design, with 30 nursing students in both the experimental and control groups. Data were collected from 3rd of July to 11th of Aug. The educational program was configured in four stages over four weeks. An after- program post-test was conducted for one week. Results : Statistically significant differences were observed in the experimental group's pre and post-results for practice confidence, practice immersion, and practice satisfaction. Significant differences were found in scores for practice confidence, practice immersion, and practice satisfaction between the experimental and control groups. Conclusion : Case-based Extended Reality content programs were found to be effective for nursing college students in terms of practice confidence, practice immersion, and practice satisfaction. It is expected that this study will serve as fundamental material for the development of various case-based extended reality content education programs.
Content Analysis of Nurses' Perceptions of Work-Life Balance
Authors:   Korean Society of Nursing Research, Ko Ga Yeon , Choi Ji Hyun , Park Sang Yong , Bae So Hyun
Published: January 2024

Purpose : This study aimed to provide foundational insights into various issues related to work-life balance by analyzing interview data on how nurses perceive this concept. Methods : Conducted as a descriptive exploratory research, data were collected from 80 nurses in Seoul and Gyeonggi Province from August 1 to September 20, 2023. Results : Applying content analysis, the study identified four domains, twelve categories, and twenty-two meaningful statements, shedding light on nurses' perceptions of work-life balance. Conclusion : This research contributes to understanding nurses' awareness of work-life balance and can serve as foundational data for improving hospital organizational culture to enhance nurses' work-life balance.
Dor osteomuscular relacionada ao trabalho e sua influência na qualidade de vida de professores que atuam na comunidade de Itacoanzinho no município do Acará-PA
Authors: Da Silva Patrick Silva , De Almeida Isabelle Marcele Alves , Gonçalves Jamile Thayane da Silva , Duarte Lorena de Amorim , França Iranete Corpes Oliveira , Do Couto Mayra Hermínia Simões Hamad Farias , Mendes Thaynara Cordeiro , Da Fonseca Ramilly Benaion
Published: January 2024

OBJETIVO: Analisar se a dor osteomuscular relacionada ao trabalho influenciará a qualidade de vida de professores que atuam na comunidade de Itacoanzinho no município do Acará- Pará. MÉTODOS: Estudo transversal, do tipo observacional, desenvolvido em agosto de 2022. Foram avaliados 18 professores, com idades de 24 a 65 anos. Utilizou-se o Questionário Nórdico de Sintomas Osteomusculares para avaliar a presença de dor; e para classificar a percepção e medição da dor, a Escala Multidimensional de Avaliação de Dor; além do questionário de Estado de Saúde, o SF-36 para avaliar a qualidade de vida. RESULTADOS: A prevalência de dores osteomusculares nos últimos 12 meses foi de 100% e de 66,7% nos últimos 7 dias entre os entrevistados. Constatou-se que 83,3% dos participantes, relataram mais de um local com queixas álgicas nos últimos 12 meses.  Ademais, os domínios que avaliaram a qualidade de vida dos participantes variaram em bom (2 domínios), regular (4 domínios) e ruim (2 domínios). CONCLUSÃO: Apenas o domínio Capacidade Funcional apresentou correlação negativa forte com a intensidade da dor, de maneira que, quanto maior o nível de dor osteomuscular, menor será a Capacidade Funcional dos professores, repercutindo de forma negativa na qualidade de vida desses profissionais.
Púrpura Trombocitopênica Trombótica - aspectos epidemiológicos, fisiopatológicos e manejo terapêutico
Authors: Da Silva Lorena Alves , Borges Lucas Paniago , Lima Nathália Sisconetto , De Faria Thaís Guimarães , Resende Thiago
Published: January 2024

A Púrpura Trombocitopênica Trombótica (PTT) é um distúrbio hematológico raro, caracterizado pela formação de microtrombos que levam a complicações graves como anemia hemolítica, febre, trombocitopenia, disfunção renal e neurológica. A PTT pode ser imunomediada ou congênita, sendo a primeira responsável pela maioria dos casos. A fisiopatologia envolve a deficiência da protease ADAMTS13, levando à formação de trombos disseminados. Nesse sentido, a ausência ou diminuição da protease ADAMTS13 é a principal causa da doença, resultando na acumulação de grandes multímeros de fator de Von Willebrand. A PTT, embora infrequente, apresenta alta taxa de mortalidade sem tratamento adequado. A doença afeta principalmente adultos, com incidência aumentando após os 40 anos, sendo mais prevalente em mulheres. O diagnóstico é desafiador devido à sobreposição de sintomas com outras condições e inclui a avaliação da atividade do ADAMTS13, com um sistema de pontuação chamado PLASMIC usado como ferramenta de triagem. O tratamento inicial consiste em plasmaférese e corticoides, seguido por rituximabe em casos refratários. A esplenectomia e o caplacizumabe são considerados em situações mais graves. Apesar dos avanços no tratamento, a PTT ainda apresenta desafios, com a necessidade de acompanhamento contínuo para prevenção de recaídas. As complicações agudas e crônicas, como isquemia mesentérica, infarto do miocárdio e alterações cognitivas, contribuem para a morbimortalidade associada à doença. O acompanhamento regular da atividade do ADAMTS13 é fundamental para a gestão a longo prazo.
Atendimento inicial ao paciente politraumatizado
Authors: De Oliveira Marina Targino , Nogueira Waléria Bastos de Andrade Gomes , Cavalcanti Lorena Ferreira , Nóbrega Katia Simone de Araújo , Costa Marcos Antônio Jeronimo , Cavalcanti Tânia Regina Ferreira , Moreira Luzia Sandra Moura , Andrade Smalyanna Sgren da Costa
Published: January 2024

Um paciente Politraumatizado é caracterizado por apresentar lesões em dois ou mais sistemas, sendo necessário que pelo menos uma, ou uma combinação dessas lesões, represente um risco vital. O atendimento inicial aos pacientes vítima de traumas requer agilidade e habilidade por meio de uma equipe altamente capacitada, onde a abordagem seja efetiva, diminuindo os riscos de uma possível evolução ao óbito do paciente. O sistema ATLS (Advanced Trauma Life of Support) tem o intuito de esquematizar e padronizar a abordagem inicial ao paciente e é utilizado como um protocolo nos atendimentos de emergência. O presente estudo tem como objetivo avaliar os conceitos atuais relacionados às abordagens clinicas associadas ao atendimento inicial do paciente politraumatizado. Trata-se de uma revisão integrativa com a seguinte questão norteadora do estudo: O que vem sendo produzido sobre a atendimento inicial ao paciente politraumatizado nos últimos 5 anos? A pesquisa foi realizada a partir do portal da BVS (Biblioteca Virtual de Saúde), nas seguintes bases de dados: LILACS (Literatura Latino-americana e do Caribe em Ciências Sociais e da Saúde); BDENF (Banco de Dados de Enfermagem), MEDLINE (Medical Literature Analysis and Retrieval System on-line) e também na SCIELO (Scientific Eletronic Library Online). Essa busca foi realizada no período de setembro e Outubro de 2021 utilizando a terminologia em saúde consultada nos Descritores em Ciências da Saúde (DeCS/Bireme): Traumatismo Múltiplo, Emergência em Enfermagem, Cuidados de Suporte Avançado de Vida no Trauma.
Fechamento de diastema entre incisivos centrais com aparelho ortodôntico: relato de caso
Authors: Lopes Filho Hibernon , Ferreira Sarah Girlayne Soares Bomfim , Silva Taís Mikaelly Santos , E Silva Laryssa Firmino de Lima , De Araújo Letícia Maia , Dos Santos Juliana Pereira , Romão Dayse Andrade , Rodrigues Raphaela Farias
Published: January 2024

Diastema é considerado como um espaço entre dois dentes na arcada dentária superior ou inferior, sendo mais frequente na região superior entre os incisivos centrais, afetando a estética e trazendo incomodo ao paciente. É comum e normal apenas durante o período de dentição decídua, onde os diastemas são fisiológicos chamados de espaços primatas, e na dentição mista que logo após desaparece, sendo sua etiologia multifatorial. O objetivo desse trabalho é relatar um caso clinico de uma paciente com diastema entre os incisivos centrais superior, onde se optou realizar o fechamento de diastema por meio do tratamento ortodôntico com aparelho parcial fixo.
Abordagens farmacológicas para a prevenção de recaídas em Depressão
Authors: Carvalho Anna Lecticia Martins de Araujo , Lima Camila Costa da Guerra , Guirra Alexandre Nascimento , Duarte Neto Jarbas Gomes , Guirra Ellen Haiany Nascimento , De Franca Weudson Cabral , Calçada Marcela Nunes , Kato Ana Beatriz Doufem , Martins Bruna Menezes , Da Costa Karina Araújo Martins , Leal Maria Paula Barcelos Hundertmark , Gomes Maria Fernanda de Almeida , Guedes Eduarda Silva , Wagner Pedro Bodart , Carneiro Amanda Martins , Araruna Pedro Nogueira , Braga Maurilio Camacho , Bastos Júlia Câmara Caldeira , Matos Amanda Sousa , Gontijo Danton Dornelas , Borges Filho Gilson Mariano , Melo Kedson Mateus da Silva Milhomem , Magalhães Rodrigo Viana , Segundo Grimaldo Carlos Ferreira Carvalho , Giroto Caroline Prado
Published: January 2024

As abordagens farmacológicas para a prevenção de recaídas em depressão desempenham um papel crucial na gestão contínua do transtorno. A personalização do tratamento, monitoramento atento e colaboração entre profissionais de saúde mental são elementos essenciais para otimizar os resultados e melhorar a qualidade de vida dos pacientes que enfrentam esse desafio persistente. Este estudo teve como objetivo avaliar o papel das abordagens farmacológica para a prevenção de recaídas em depressão. Para isso, se realizou uma revisão sistemática da literatura, utilizando as bases de dados Scielo, Lilacs e Medline. Com a análise qualitativa dos resultados, concluiu-se que as intervenções farmacológicas desempenham um papel significativo no cuidado mental, proporcionando benefícios em diversas situações. Contudo, o limite reside na necessidade de abordar cuidadosamente os desafios associados a essas intervenções e reconhecer a diversidade de respostas individuais à terapia farmacológica.
O uso do remifentanil em sedação venosa para broncofibroscopia: um relato de caso
Authors: Lima Junior Ari Antônio Stein , Costa Carolina Seith Casotti , Da Penha Neto Jocelym Rodrigues , Força Lucas Ferreira
Published: January 2024

A broncoscopia flexível continua sendo padrão-ouro para inúmeras intervenções diagnósticas e terapêuticas em patologias pulmonares. Diante disso, uma sedação apropriada, individualizando cada perfil de paciente, visando conforto ao paciente, associado à manutenção hemodinâmica e recuperação rápida, pode ajudar o broncoscopista e facilitar o exame. Neste cenário, foi descrito um caso incomum do uso do remifentanil como única medicação endovenosa em infusão contínua, levando em consideração a sua farmacologia e propriedade conservadora de drive respiratório em quantidades tituladas.
Application of some Plant Extracts as Biocolorants for Leather During Finishing Process
Authors: Mirzamuratova Roza , Bayramoğlu Eser Eke , Kaldybayev Rashid
Published: January 2024

In this research, chrome-tanned bovine crust leathers were dyed during the finishing process using plant extracts: walnut shell (Juglans regia), oak bark (Quercus cortex), and onion peel (Allium cepa). In this study, the standard recipe applied by the factory was used in the leather finishing process. For this recipe, various plant extracts were used instead of pigments, and groups that did not contain pigment and any dyestuff were formed as the control groups.
After these processes, color measurement analyzes were performed on Konica Minolta CM 3600d spectrophotometer. In order to investigate the effects of walnut shell (Juglans regia), oak bark (Quercus cortex), and onion peel (Allium cepa) on the other performance properties of leather, dry and wet rub fastness test according to standard method TS EN ISO 11640 (2001) was performed. The results of the study were statistically evaluated using the NCSS method (Number Cruncher Statistical System). As a result of the study, it was noticed that, depending on the extract, different colors were obtained. It was found that the dry and wet fastness of leathers treated with plant extracts improved.
LIFE EXPECTANCY FOR THE REGIONS OF THE NORTHWESTERN FEDERAL DISTRICT. PART 1: DYNAMICS OF LIFE EXPECTANCY AT OLDER AGES
Authors: Сафарова Г.Л. , Сафарова А.А.
Published: January 2024

При исследовании процесса старения населения значительное внимание неизменно уделяют смертности и ее обобщающей характеристике — ожидаемой продолжительности жизни (ОПЖ). Проанализирована динамика ОПЖ мужчин и женщин в старших возрастах в регионах, входящих в состав Северо-Западного федерального округа. Показано, что во всех рассмотренных регионах во всех рассмотренных старших возрастах в начале периода реформ ОПЖ снижалась, затем с начала 2000-х гг. она росла до 2019 г., после чего снизилась. Установлено, что в характере динамики ОПЖ в старших возрастах нет принципиальных различий между мужским и женским населениями, но имеет место значительный разрыв в величине ОПЖ. Показано, что в динамике ОПЖ в старших возрастах нет принципиальных различий между рассмотренными регионами. При этом наибольшее снижение ОПЖ у населения старших возрастов после 2019 г. произошло именно в тех регионах, где наблюдался наибольший рост ОПЖ в период с начала 2000-х до 2019 г. Как относительный рост, так и относительная убыль ОПЖ с возрастом увеличиваются и для мужчин, и для женщин.

When studying the process of population ageing, much attention is invariably paid to mortality and its generalizing characteristic, life expectancy (LE). The dynamics of LE of men and women at older ages in the regions of the North-Western Federal District has been analyzed. It is shown that in all the regions considered, in all considered older ages, life expectancy decreased at the beginning of the reform period, then from the beginning of the 2000s it grew until 2019, after which it decreased. It has been shown that there are no principal differences between the male and female populations in the character of the dynamics of LE at older ages, but there is a significant gap in the value of life expectancy at older ages between them. It is shown that there are no fundamental differences in the dynamics of life expectancy at older ages between the regions considered. The largest decrease in LE at older ages after 2019 took place just in those regions where the largest increase in LE was observed in the period from the beginning of the 2000s to 2019. Both the relative increase and the relative decrease in life expectancy rise with age for both men and women.
The Impact of Housing Supply Through Housing Construction Projects on Nearby Apartment Prices : Focusing on the Case of Heukseok3 Development Area and the Vicinity
Authors:   Korea Real Estate Research Institute, Bae Yeong Gon , Kang Chang Deok
Published: January 2024

Seoul City continues to promote urban development projects to respond to the increasing housing demand due to continued population growth and urbanization. Furthermore, it is establishing related support policies. This study analyzes the impact of housing supply through redevelopment projects, especially on apartment resale prices in the vicinity and provides insights for relevant policy development. Accordingly, the Heukseok 3 redevelopment area was selected as the target site, and apartment complexes within 500 m, 1 km, and 1.5 km of the target site were established as the treatment group, control group 1, and control group 2, respectively, with a total of 10,300 cases in 14 apartment complexes. The analysis used the difference-in-differences method and multilevel modeling. The results obtained at various stages of the project implementation indicated that the prices of the surrounding apartments decreased during the association establishment and completion approval stages, whereas price increases were observed during the project design and property management and disposal planning phases. Moreover, the extent of price increases and decreases varied with distance from the Heukseok 3 zone oriented to the policy. Through this study, we confirmed the impact of housing supply through redevelopment projects in neighboring areas. These findings can serve as valuable evidence for future housing policy development.
Analysis of Practicing Domestic Trends in Continuity between Preschool and Elementary Education
Authors:   Korean Society for  Holistic Convergence Education, Kim Ho , Jang Won Ho
Published: January 2024

This study was conducted to examine the domestic practicing trends of continuity between preschool and elementary education, and to confirm what future tasks will be for leum education in the future. The subjects of this study are 56 cases of continuity between preschool and elementary education practices for young children, and supporting teachers and parents on continuity between preschool and elementary education. In this study, the text presented in the analysis data was examined using the content analysis method, and then the frequency by category was calculated and cases were analyzed. As a result of the study, first, “continuity between preschool and elementary education practices through curriculum implementation” was the most common with 66 times, and relatively the least with 0 training for childcare teachers, 0 conference for childcare teachers, and 1 conference for parents. Second, in terms of curriculum implementation, continuity between preschool and elementary education provides an opportunity for young children to explore elementary schools on their own, but most of them are one-time experience activities, and literacy and learning were also emphasized from the perspective of learning readiness. In terms of strengthening teachers and parents' capabilities, continuity between preschool and elementary education focuses on understanding the curriculum, and the conference was primarily centered on kindergarten teachers or was conducted as a one-time meeting between parents before and after school. In terms of creating an educational environment, continuity between preschool and elementary education formed a common space and a play space in the classroom of the first grade of elementary school and opened a new integrated school, but there were few attempts to link it with existing private kindergartens and daycare centers. Through the results, the study suggests the implementation of continuity between preschool and elementary education that reflects the subjectivity of young children, and the discovery of cases of continuity between preschool and elementary education that utilize community resources and support various young children's characteristics.
A study to explore the operation of School-Based Enterprise Support Project from the perspective of Resource Dependence theory
Authors:   Korean Society for  Holistic Convergence Education, Tschang Young-Ho , Jang Deok-Ho
Published: January 2024

The purpose of this study is to identify the problems of the School-Based Enterprise system and diagnose the causes and patterns of resource-dependence of School-Based Enterprise support projects in terms of organizational theory. To this ends, three rounds of FGI were conducted with field stakeholders (professors, practitioners) who have operated school-based enterprises and participated in support projects and experts who have conducted related research.
The results showed that the regulatory laws and systems underlying the establishment and operation of school-based enterprise hindered its stable operation. In addition, the goals set for the organization were higher than the capacity of the organization, which caused considerable burden on school-based enterprises. In addition, the school-based enterprise support project provided essential resources for the operation of the organization, but the performance indicators and selection and evaluation methods added to the burden of school-based enterprises. Overall the above factors hindered the activities of school-based enterprises preventing them from achieving internal organizational innovation and organizational growth as a unique enterprise.
Based on the results of the study, it was suggested that regulatory reform of the school-based enterprise system should be carried out to realize the transformation of entrepreneurial universities and achievement of university innovation and that performance indicators should be improved and step-by-step support should be provided to prevent the problem of resource dependence in higher education financial support projects.
Exploration and Recommendations for Teacher Training Approaches in Integrating Technology into Physical Education Classes
Authors:   Korean Society for  Holistic Convergence Education, Lee Je-Haeng , Baek Jun-Hyung
Published: January 2024

The purpose of this study is to identify the reasons behind the slow adoption of technology in physical education(PE) and to suggest strategies to prepare PE teachers who can integrate technology into PE class. To achieve this, the study utilizes theories from teacher beliefs and decision-making research to analyze these underlying reasons and introduces a new framework called C.O.P.S. The C.O.P.S. framework is developed based on decision-making research and is aimed at facilitating the adoption of technology. In order to effectively promote PE teacher’s technology adoption, an understanding of the fundamental reasons why they may hesitate to embrace technology and the challenges they may face during the adoption process is necessary. The C.O.P.S. framework proposed in this paper can provide crucial guidance and principles for concretely shaping and designing technology adoption plans.