bluuebunny/crossref_metadata_2025 huggingface dataset:
Polymeric Nanogels for Theranostic Applications: A Mini-Review
Authors: Vijayan Vineeth M. , Vasudevan Pradipika Natamai , Thomas Vinoy
Published: July 2019

Theranostics is a recently emerging area in nanomedicine. Nanoparticles which can combine
both diagnostic and therapy in one single platform serve as theranostic agents. Some of the currently
explored nanoparticles are metallic nanoparticles, mesoporous silica nanoparticles, carbonbased
nanoparticles, and polymer nanogels. Polymeric nanogels are receiving considerable attention
due to their high biocompatibility and functional performance. The present review article briefly
summarizes the scopes and challenges of the state of art of using polymeric nanogels for theranostic
applications. Among the different polymer nanogels, a special emphasis is given to polymeric nanogels
with innate imaging potential.
Research on Gastric Cancer’s Drug-resistant Gene Regulatory Network Model
Authors: Li Zhi , Zhang Tianyue , Lei Haojie , Wei Liyan , Liu Yuanning , Shi Yadi , Li Shuyi , Shen Bowen , Guo Hao , Chen Zhangqian , Yi Xiaorong , Zhang Hao
Published: July 2019

Objective:

Based on bioinformatics, differentially expressed gene data of drug-resistance in
gastric cancer were analyzed, screened and mined through modeling and network modeling to find
valuable data associated with multi-drug resistance of gastric cancer.

Methods:

First, data sets were preprocessed from three aspects: data processing, data annotation
and classification, and functional clustering. Secondly, based on the preprocessed data, each
classified primary gene regulatory network was constructed by mining interactions among the
genes. This paper computed the values of each node in each classified primary gene regulatory
network and ranked these nodes according to their scores. On the basis of this, the appropriate core
node was selected and the corresponding core network was developed.

Results and Conclusion::

Finally, core network modules were analyzed, which were mined. After
the correlation analysis, the result showed that the constructed network module had 20 core genes.
This module contained valuable data associated with multi-drug resistance in gastric cancer.
Products of Dental Use Containing Copaiba Oil-resin: Technological Prospecting Based on Patents
Authors: Valadas Lidia Audrey Rocha , de Oliveira-Filho Rosueti Diógenes , de Oliveira Marcelo Bruno Lemos , de Mello Fiallos Ana Cristina , Lotif Mara Assef Leitão , de França Fonteles Marta Maria , Bandeira Mary Anne Medeiros
Published: July 2019

Background:

Copaiba oil-resin has been widely used and is especially found in
neotropical regions, for which several pharmacological activities have been documented over the
years. Prospective studies in intellectual property banks are important to increase competitiveness
and thus generate new products in various research areas.

Objective:

A prospective study was carried out on patents of products containing copaiba oil-resin
for dental use in intellectual property banks.

Methods:

The research was conducted with patent searches in six intellectual property banks of
the world. Relevant information about the invention in the patent document was collected, processed
and described.

Results:

The search found 9 patents using copaiba resin oil-resin in dental products. The National
Institute of Industrial Property (INPI-Brazil) had the highest number of deposits (5), followed by
Espacenet (2) and Free Patents (2). C. Langsdorffii was highlighted as the most widely used species
in the products and deposits of vehicles in formulations (3). All the patents in the search are
A61K code for medical, dental or hygienic purposes.

Conclusion:

Most of the found patents are related to the area of Microbiology, specifically with
application in Cariology. Brazil is represented by the INPI and presented the highest number of
patent applications when compared to other intellectual property banks.
A Comprehensive Analysis of Image Forensics Techniques: Challenges and Future Direction
Authors: Ansari Mohd D. , Rashid Ekbal , Skandha S. Siva , Gupta Suneet K.
Published: July 2019

Background:

Image forensics deal with the problem of authentication of pictures or
their origins. There are two types of forensics techniques namely active and passive. Passive forgery
is also known as blind forensics technique. In passive forgery, copy-move (cloning) image forensics
is most common forgery technique. In this approach, an object or region of a picture is copied
and positioned somewhere else in the same image. The active method used watermarking to
solve picture genuineness problem. It has limitations like human involvement or particularly
equipped cameras. To overwhelm these limitations, numerous passive authentication approaches
have been developed. Moreover, both approaches do not require any prior information about the
picture.

Objective:

The prime objective of this survey is to provide an inclusive summary as well as recent
advancement, challenges and future direction in image forensics. In today’s digital era, digital pictures
and videos are having a great impact on our life as well as society, as they became an important
source of information. Though earlier it was very difficult to doctor the picture, nowadays
digital pictures can be doctored easily with the help of editing tools and the internet. These practices
make pictures as well as videos genuineness deceptive.

Conclusion:

This paper presents the current state-of-the-art of passive (cloning) image forensics
techniques, challenges and future direction of this research domain. Furthermore, the major open
issues in developing a robust cloning image forensics detector with their performance are discussed.
Lastly, the available benchmark datasets are also discussed.
Effects of Ultraviolet Pretreatment on Pigment Printing of Cotton / Polyester Blend Fabric
Authors: Zolriasatein Ali A.
Published: July 2019

Introduction:

Pigments have become the largest colorant group for textile prints because
pigment printing is the oldest and cheapest method. Binders are used to fix pigments to the fibers by
adhesion. Pigment binders play a significant role in pigment printing because it encloses the pigment
particles and adheres to the fiber.

Objective:

In this study, cotton/polyester blend fabrics were treated with ultraviolet light (UVB) at an
air pressure of 1 atm to improve printability.

Methods:

To study the influence of pretreatment time, experiments were carried out at different exposure
times. Untreated and UV treated fabrics were analysed by Fourier-transform infrared spectroscopy
to investigate changes in the chemical composition of fabrics. It was observed that carbonyl
groups were formed on the surface of UV pretreated cotton fibers. Scanning Electron Microscopy
(SEM) was used to investigate the roughness and cracks on the treated fiber surface. Then, all UV
treated and untreated fabrics were screen printed with different kinds of pigments. The color strength
of the printed fabrics and fastness properties to washing and dry/wet rubbing were evaluated.

Results:

Experimental data showed that atmospheric UV pretreatment led to an increase in pigment
uptake. Moreover, UV pretreated fabrics had better dry and wet rubbing fastness compared with
untreated fabrics.

Conclusion:

The washing fastness of UV pretreated fabric showed no significant change and was
comparable with that of untreated fabric. The loss in tensile strength of UV pretreated fabrics was
greater than untreated samples.
Therapeutic Promises of Chlorogenic Acid with Special Emphasis on its Anti-Obesity Property
Authors: Kumar Rajnish , Sharma Anju , Iqbal Mohammed Shariq , Srivastava Janmejai K.
Published: July 2019

Background::

Chlorogenic acid (CGA) is a quinic acid conjugate of caffeic acid. It is an ester
formed between caffeic acid and the 3-hydroxyl of L-quinic acid. This polyphenol is naturally present
in substantial amount in the green coffee beans. Minor quantities of CGA are also reported in apples,
eggplant, blueberries, tomatoes, strawberries and potatoes. CGA is reported to be beneficial in hypertension,
hyperglycemia, antimicrobial, antitumor, memory enhancer, weight management etc. Further, it
is also reported to have anticancer, antioxidant and anti-inflammatory activities. Since the last decade,
CGA drew public attention for its widely recommended use as a medicine or natural food additive supplement
for the management of obesity.

Objective:

The current review explores the medicinal promises of CGA and emphasizes on its antiobese
property as reported by various scientific reports and publication.

Conclusion:

CGA shows promises as an antioxidant, glycemic control agent, anti-hypertensive, antiinflammatory,
antimicrobial, neuro-protective and anti-obesity agent. It primarily activates the AMPactivated
protein kinase, inhibits 3-hydroxy 3-methylglutaryl coenzyme-A reductase and strengthens the
activity of carnitine palmitoyltransferase to control the obesity.
The Reproduction Health Behavior of High School Teenagers in Semarang, Indonesia
Authors: Handayani Oktia Woro Kasmini , Wiranti Iin , Raharjo Bambang Budi , Nugroho Efa
Published: July 2019

Background:

It is recorded in Semarang that nearly 50% of the teenagers have conducted premarital sexual intercourse at the age 10-15 years. One of the efforts to prevent it is by reproduction health education at school to improve the teenagers’ knowledge and health behavior.

Objective:

The research objective is to find out the relation of school role in health education with reproduction health behavior on high school teenagers in Semarang.

Methods:

The research was conducted in 2017, which is a correlation description research with a quantitative approach. The population is all high school students in Semarang, i.e. 6620 students, the sample taking technique is by purposive sampling with 178 respondents. Questionnaire instruments were used to collect data on the role of schools and adolescent reproductive health behaviors. The questionnaire was tested for validity and reliability first. In addition, additional instruments such as APARQ are used, which are standard questionnaires for measuring physical activity and standard recall, so validity and reliability tests are not needed. Data was analysed using univariate, bivariate and multivariate with SPSS.

Results:

There was a significant role of school in the teenager’s reproduction health behavior (p-value 0.023), there was no significant effect of the dating status on the teenager reproduction health behavior with (p-value 0.693), there was a significant effect of teenager knowledge to teenager reproduction health behavior (p-value 0.012) and there was no significant relation between teenage physical activity and teenager reproduction health behavior in Semarang (p-value 0.370).

Conclusion:

The role of the school is directly related through knowledge to the reproduction health behavior where the policy and activity have the highest effect on knowledge. Moreover, age, dating status, and physical activity do not directly relate to the reproduction health behavior of high school teenagers in Semarang. Besides, result demonstrate that school has a high role in teenager knowledge compared to other variables in this research.
Cyclo(L-Pro-L-Tyr) from Streptomyces sp. 150: Exploiting in vitro Potential in Controlling Foodborne Pathogens and Phytopathogens
Authors: Rahman Atiqur , Siddiqui Shah A. , Rahman M. Oliur , Kang Sun C.
Published: July 2019

Background:

In the prokaryotic unicellular bacteria, Streptomyces species are the most frequent producers of bioactive secondary metabolites. Our continuous quest for new antibiotics from Actinomycetes genera put us forward for isolation of a strain Streptomyces sp. 150 from the soil samples collected at the Daegu University premises in Korea.

Objective:

The aims of this study was to isolate and identify bioactive compounds from the isolated microorganism and assess the efficacy of the compounds in controlling foodborne pathogens and phytopathogens.

Methods:

The isolated bacterium was characterized by the taxonomic analyses and a compound was isolated from the fermentation broth by applying different chromatographic techniques e.g. column chromatography, TLC and PTLC. The structure of the compound was established by UV, IR, 1H-NMR and 13C-NMR spectral data analyses. The antibacterial and antifungal efficacy of the compound was assessed by disc diffusion assay, poisoned food technique, MIC determination and SEM analysis.

Results:

Different chromatographic techniques resulted in isolation and purification of a secondary metabolite from the fermentation broth of Streptomyces sp. 150. The analyses of the spectroscopic data identified the compound as cyclo(L-Pro-L-Tyr). The compound exhibited potential efficacy in controlling all the seven foodborne pathogenic bacteria with corresponding inhibition zone and minimum inhibitory concentration (MIC) ranging from 15.1 to 20.1 mm and 15.6 to 62.5 μg/mL respectively, and tested phytopathogenic fungi with mycelium growth inhibition varying from 57.1 to 68.5% and MIC from 125 to 250 μg/mL. Moreover, in scanning electron microscopy, morphological changes in Listeria monocytogenes ATCC 19166 at MIC dose of compound was observed.

Conclusion:

This study demonstrated the possibility to use the compound cyclo(L-Pro-L-Tyr) in food and agrochemical industries to control foodborne pathogens and phytopathogens.
Comparison of Fluid Flow and Heat Transfer Through Metal Foams and Wire Mesh by Using CFD
Authors: Kotresha Banjara , Gnanasekaran Nagarajan
Published: July 2019

Background:

The unique structural characteristics of the metal foams, such as low density,
large surface area, ability to increase turbulence, and increased heat transfer efficiency, are the advantages
associated with thermal applications such as electronics cooling, refrigeration air conditioning,
etc. The porous metal foam structures are extensively used to enhance heat transfer.

Objective:

This paper discusses the numerical simulations of a vertical channel filled with metal foam
and wire mesh. The fluid flow and heat transfer phenomena of a wire mesh are compared with two
different types of metal foams. Metal foams are made of aluminium and copper while the wire mesh is
made of brass. The porosity of the metallic porous structures varies from 0.85 to 0.95.

Methods:

A Darcy extended Forchheirmer model is considered for solving fluid flow through the
porous media while the heat transfer through the porous media is predicted using local thermal
non-equilibrium model.

Results:

Initially, the results obtained using the proposed numerical procedures are compared with
experimental results available in the literature. The numerical simulations suggest that the pressure drop
increases as the velocity of the fluid increases and decreases as the porosity increases. The heat transfer
coefficient and Nusselt number are determined for both the metal foams and the wire mesh.

Conclusion:

The Nusselt number obtained for wire mesh shows almost 90% of the copper metal foam
in the same porosity range. The numerical results suggest that the brass wire mesh porous medium can
also be used for enhancement of heat transfer. In this article, patents have been discussed.
Marcadores de selección en cerdos Pampa Rocha: comparación con razas autóctonas de España y Portugal
Authors: Burgos Serrano Carmen , Llambí Dellacasa Silvia , Hidalgo Gracia Jorge , Montenegro Silva Maria , Arruga Laviña Victoria , López-Buesa Pascual
Published: July 2019

Objetivo. El análisis de marcadores de selección permite obtener datos de la vida evolutiva de una raza o línea y permite también evaluar la conveniencia o no de su uso en programas de mejora genética. Hemos evaluado SNPs en cuatro genes (IGF2, MC4R, PRKAG3 y PEPCK-C), que tienen importantes efectos fenotípicos, en cerdos de la raza Pampa Rocha, una raza criolla, y hemos comparado sus frecuencias alélicas con cerdos de diversas razas autóctonas y líneas de España y Portugal no sometidas a selección así como con jabalíes y cerdos de la raza Piétrain. Materiales y métodos. Los SNPs fueron analizados mediante diversa técnicas de RT-PCR. Resultados. Los resultados de los análisis muestran una similitud de frecuencias alélicas entre los cerdos de la raza Pampa Rocha y los cerdos autóctonos de la península ibérica sobre todo en el gen IGF2 y, en menor medida en el gen PEPCK-C. Sin embargo difieren considerablemente en el caso del marcador MC4R y, también en menor medida, en PRKAG3. En el trabajo se discute el uso potencial de los resultados obtenidos para orientar la selección genética de cerdos de la raza Pampa Rocha. Conclusiones. Nuestros resultados demuestran la peculiaridad de la raza Pampa Rocha con respecto a los marcadores estudiados.
Evaluación genética para características de peso en ganado Brahman comercial
Authors: Bedoya Ospina Christian Fernando , Alzate Ramirez Jovany Andrés , Ángel Cardona Juan Camilo , Escobar R Carlos Santiago , Calvo Cardona Samir Julián
Published: July 2019

Objetivo. Evaluar genéticamente las características de peso al nacimiento y peso al destete en una población de ganado Brahman comercial. Materiales y métodos. Se analizaron 1.015 registros de peso al nacimiento (PN) y peso al destete ajustado a los 270 días (PA270) de crías entre los años 2002 y 2014 pertenecientes a la hacienda La Envidia, ubicada en el municipio de Planeta Rica-Córdoba. Se utilizó un modelo animal bi-carácter que incluyó efectos fijos de sexo, mes, año y edad al destete, efecto genético aditivo y el efecto materno, estimando los parámetros genéticos con el software MTDF-REML. Resultados. Se encontró un promedio para PN de 29.62±3.13kg y coeficiente de variación (CV) del 10.6%. La media para PA270 fue de 216.713±26.97kg y CV 12.5%. Los estimados de heredabilidad directa fueron de 0.44±0.14 y 0.39±0.12 para PN y PA270, respectivamente. La heredabilidad materna fue de 0.09±0.092 y 0.42±0.087 para PN y PA270, respectivamente. La correlación genética y fenotípica estimada entre las características evaluadas fue de 0.11 y 0.13, respectivamente; con progreso genético por año para PN de -2.02 y 7.81kg para PA270. Conclusiones. Las estimaciones de heredabilidad indican la existencia de variabilidad genética aditiva directa, evidenciando la oportunidad de ganancia genética por medio de selección. Sin embargo, las características de peso al nacer y peso del destete presentan gran influencia del ambiente, por lo cual se debe poner especial atención al manejo y la nutrición de las hembras durante la gestación y de los terneros desde el nacimiento hasta el destete.
Equilibrio, cinética y termodinámica de la adsorción del colorante DB-86 sobre carbón activado de la cáscara de yuca
Authors: Castellar-Ortega Grey , Mendoza Colina Evert De  Jesus , Angulo Mercado Edgardo Ramon , Paula Pereira Zilena Alejandra , Rosso Bravo María Camila , Jaramillo Colpas Javier Enrique
Published: July 2019

Objetivo. Establecer mediante experimentos por lote la capacidad de remoción, la cinética y termodinámica de adsorción del carbón activado preparado a partir de la cáscara de yuca (Manihot esculenta) en la remoción del colorante azul directo 86. Materiales y métodos. La metodología experimental consistió en la preparación del carbón activado por activación química de la cáscara de yuca con H3PO4 y su posterior calcinación a 530°C. En la caracterización se determinaron las propiedades de textura mediante el índice de yodo e índice de azul de metileno, se cuantificaron los grupos funcionales orgánicos ácidos y básicos con el método Boehm. En el estudio por lote, el efecto de varios parámetros sobre la capacidad de adsorción fueron evaluados: el pH (2,4,8 y 10), la temperatura (25,30 y 40°C) y la concentración inicial de colorante (20,40,60,80 y 100 mg/L). Tanto las características fisicoquímicas como los ensayos de adsorción del carbón activado fueron comparadas con otro de marca comercial (CAM). Resultados. Los resultados de la caracterización indican que ambos carbones tienen una química de superficie heterogénea, de naturaleza ácida para el CAY y básica para el CAM. La máxima capacidad obtenida fue 6.1 mg/g para el CAY y de 3.7 mg/g para el CAM. Los cálculos termodinámicos indican que la remoción es espontánea y para ambos carbones la cinética se ajusta al modelo de pseudo segundo orden. Conclusión. El carbón activado obtenido a partir de la cáscara de yuca puede considerarse un adsorbente eficiente en la remoción de colorantes.
Hubungan antara Kebijaksanaan dengan Kepuasan Hidup pada Remaja
Authors: Raharja Belladina N , Indati Aisah
Published: July 2019

Adolescence is the transition from childhood to adulthood with all the changes in it. They have various needs that must be fulfilled to produce life satisfaction. If their needs were not fulfilled, they are vulnerable to vent through negative things. But there are also adolescents whose needs are not met and they still feel the satisfaction of life.This study was conducted to determine the positive relationship between wisdom with life satisfaction among adolescents. Participants in this study were 105 subject. The study hypothesized that there is a significant positive relationship between wisdom and life satisfaction among adolescents. The data on this study was obtained by using Likert scales for Three Dimensional Wisdom Scale and Brief Multidimensional Student’s Life Satisfaction Scale. Finding suggest a significant positive relationship between wisdom with life satisfaction among adolescents.
Efikasi Diri Akademik dan Resiliensi pada Siswa SMA Berasrama di Magelang
Authors: Oktaningrum Arista , Santhoso Fauzan Heru
Published: July 2019

This study aims to determine the relationship between academic self efficacy and resiliency of boarding-high school students in Magelang. The hypothesis of this research that there is a positive effect between two variables; academic self efficacy and resiliency. The subjects are 10th grader in X high school and totals of the subjects are 90 people. The measuring instruments used are Resilience Scale and Academic Self-efficacy Scale. The analysis of this study using simple regression analysis technique. The results can prove the initial hypothesis with R = 0.698; p = 0,000. Efficacy gives an effect of 48.7% on the increase resilience and other 51.3% influenced by other variables.
Kepemimpinan Transformasional Kepribadian Proaktif dan Desain Kerja sebagai Prediktor Perilaku Kerja Inovatif
Authors: Khasanah Iffah Fitri Nur , Himam Fathul
Published: July 2019

Every country needs innovation to support economic growth and prepare for the future of a better nation. This study aims to empirically examine transformational leadership, proactive personality, and work design in driving innovative work behavior. The hypothesis proposed is transformational leadership, proactive personality, and work design is a predictor of innovative work behavior in employees. This study used a quantitative survey approach. Methods of data collection in this study was done by spreading the scale to the subject of research. Data were analyzed using multiple regression technique. The results show that transformational leadership, proactive personality, and work design together improve employee innovation (F) = 58,032, R2 = 0,593).
Ngudari Reribet: Mulur-Mungkret dan Tatag Janda Muda Ditinggal Mati dalam Perspektif Ki Ageng Suryomentaram
Authors: Sumbodo Heru , Koentjoro Koentjoro
Published: July 2019

Widowhood is a major problem for women. This research intends to analyze phenomenologically the young widow is left behind in the perspective of Ki Ageng Suryomentaram. The aim of this study; First, deeply analyze the young widows left dead on mulur-mungkret according to Ki Ageng Suryomentaram perspective. Second, to analyze in depth tatag young widow left behind according to perspective Ki Ageng Suryomentaram. Criteria of the subject, first, women who became widows and have aged 30-45 years. Second, the subject is widow under 6 months. The results showed that, firstly, the self-regulation the developed subject is still largely on the mind and body. Both are done with the thought that his life improved, and followed by adding skills to support the independence of his life. The three subjects have not arrived at olah raos to place the problem more clearly and clearly. The three subjects have not really sumeleh (sincere). The steps taken to reduce reribet limited to out of problems, not yet to understand theirself.
Model Work Engagement Angkatan Kerja Generasi Millennial dengan Meaningful Work sebagai Mediator
Authors: Mulyati Rina , Himam Fathul , Riyono Bagus , Suhariadi Fendy
Published: July 2019

Key success for organization with millennial workforce to win the competitiveness on business industry in 4.0 era is having a compatible model of work engagement. In 2025, millennials will dominate up to 75% of the labour force. Therefore it is necessary to scientifically inquire deeper on this generation. This research adopted Job Demand Resources Model (JD-R) as theoretical framework. It specifically aimed to analyse the most suitable work engagement model among millennials who work at state owned companies. Predictor variables in this research were job crafting and meaningful work as mediator. This quantitative research (N=318) used scaling for data collection and Structural Equation Model (SEM) to test the data. This research found: 1) work engagement model fits for the millennial workforce, 2) job crafting has direct significant effect to work engagement, and 3) meaningful work plays as mediator between job crafting and work engagement.
Hubungan antara Kecerdasan Emosional, Stres Akademik, dan Kesejahteraan Subjektif pada Mahasiswa
Authors: Julika Sari , Setiyawati Diana
Published: July 2019

The objective of this study was to understand the relationship between academic stress, emotional intelligence, and subjective well-being in college student. Hypothesis for this study is academic stress and emotional intelligence can predict someone’s subjective well-being. This study utilized a quantitative survey method. Participants of this study were 132 college students from different majors who lived in Yogyakarta, men and women, with ages  varied from 18 to until 30s. Measurement tools that utilized in the study were academic stress, emotional intelligence scale, and student subjective well-being. Data was analyzed using regression analysis. Academic stress and emotional intelligence were found to predict someone’s subjective well being (F=9.862; p<0.001).
Adversity Quotient pada Pelaku Startup di Yogyakarta: Kegigihan di Tengah Masalah
Authors: Ibrahim Akbar Verezha Bintang , Sumaryono Sumaryono
Published: July 2019

The purpose of this research was to understand the adversity quotient among startup founders in Yogyakarta. Phenomenology was the approach and analyzed by Miles and Huberman interactive model. The data collection method in this research was semi-structured interview. Respondents in this study consisted of three startup founders with these criteria: 1) aged 18-24 years old, 2) age of startup at least 1 year, 3) based in Yogyakarta, 4) willing to be interviewed. This study found two forms of adversity quotient on startup founders: 1) coping strategies and 2) characters. Coping strategies encompassed immediate problem solving, having goals and visions, taking lessons from problems, and finding solutions. While the characters consisted of concepts such as responsibility, learning from experience, having strong principles, persistence, and optimism.
Peran Leader-Member Exchange (LMX) dan Occupational Stress untuk Memprediksi Intensi Turnover
Authors: Widyaningsih Ramadhan Ulfah , Saptoto Ridwan
Published: July 2019

The aim of this study was to examine the effect of leader-member exchange (LMX) and occupational stress to turnover intention on PT. Komatsu Indonesia’s employees. It was hypothesized that leader-member exchange (LMX) and occupational stress predict turnover intention together. The subjects of this study were 66 employees of PT. Komatsu Indonesia that had been working for at least 3 years. The data were obtained using turnover intention scale, LMX-MDM (Leader-Member Exchange-Multidimensional Dimension Measure) scale, and SDS (Stress Diagnostic Survey) scale. The data were analysed using multiple linear regression. Results showed that occupational stress significantly predicts turnover intention. The hypothesis was rejected because leader-member exchange (LMX) and occupational stress didn’t predict turnover intention together. The significancy level of occupational stress’s effect to turnover intention is 0.044 (p<0.05) and it explained 7.2% of turnover intention.
Access to Kidney Transplantation after a Failed First Kidney Transplant and Associations with Patient and Allograft Survival
Authors: Clark Stephanie , Kadatz Matthew , Gill Jagbir , Gill John S.
Published: July 2019

Background and objectives

Patients who have failed a transplant are at increased risk of repeat transplant failure. We determined access to transplantation and transplant outcomes in patients with and without a history of transplant failure.

Design, setting, participants, & measurements

In this observational study of national data, the proportion of waitlisted patients and deceased donor transplant recipients with transplant failure was determined before and after the new kidney allocation system. Among patients initiating maintenance dialysis between May 1995 and December 2014, the likelihood of deceased donor transplantation was determined in patients with (n=27,459) and without (n=1,426,677) a history of transplant failure. Among transplant recipients, allograft survival, the duration of additional kidney replacement therapy required within 10 years of transplantation, and the association of transplantation versus dialysis with mortality was determined in patients with and without a history of transplant failure.

Results

The proportion of waitlist candidates (mean 14%) and transplant recipients (mean 12%) with transplant failure did not increase after the new kidney allocation system. Among patients initiating maintenance dialysis, transplant-failure patients had a higher likelihood of transplantation (hazard ratio [HR], 1.16; 95% confidence interval [95% CI], 1.12 to 1.20; P<0.001). Among transplant recipients, transplant-failure patients had a higher likelihood of death-censored transplant failure (HR, 1.44; 95% CI, 1.34 to 1.54; P<0.001) and a greater need for additional kidney replacement therapy required within 10 years after transplantation (mean, 9.0; 95% CI, 5.4 to 12.6 versus mean, 2.1; 95% CI, 1.5 to 2.7 months). The association of transplantation versus dialysis with mortality was clinically similar in waitlisted patients with (HR, 0.32; 95% CI, 0.29 to 0.35; P<0.001) and without transplant failure (HR, 0.40; 95% CI, 0.39 to 0.41; P<0.001).

Conclusions

Transplant-failure patients initiating maintenance dialysis have a higher likelihood of transplantation than transplant-naïve patients. Despite inferior death-censored transplant survival, transplantation was associated with a similar reduction in the risk of death compared with treatment with dialysis in patients with and without a prior history of transplant failure.
La gestión de lo patológico:
Authors: Cavia Beatriz
Published: July 2019

In the last DSM-5 update, transsexuality is ruled out as a mental disorder and is amended to the concept of “gender dysphoria”. But what appears to be a concession to the process of depathologisation requested by different transsexual collectives continues to consolidate the medical protocols leading to the production and reproduction of a normative body within sexual differentiation. This category displacement, nonetheless, mobilises the assemblages of experts, doctors, legal and social professionals who shape the transsexual.From the bio-citizenship point of view, this re-definition places the emphasis on the mechanisms of the body’s production, both in the medical environment and in daily life. Throughout, the article unravels the different mechanisms and processes through which transsexuality is shaped as a personal space for managing the pathology, and its results can be extrapolated to some areas in which relationships with experts are being transformed. In this way, the body clocks – marked by hormones, surgical and identity modifications, collective links and care relationships – engender a scenario in which the distinction between pathology and normality interchange in turn.
Development of Agricultural Mechanization in China and Its Current Strategic Focus
Authors: Shuqi Sh. , Jiasheng W. , Dongwei W.
Published: July 2019

China's agricultural machinery development has gone through fi ve stages in its 100-year history: Germination stage of agricultural machinery development (1917-1949), Construction Stage of Modern Agricultural Machinery Industry System in China (1949-1979), System transformation Stage (1980-1995), Market-oriented stage (1996-2003), Rapid development stage (2004-2014). After the 12th Five-Year Plan, China's 13th Five-Year Plan has been going on for three years. Signifi cant Achievements in Agricultural Mechanization has also made in recent 10 years. Although Agricultural Mechanization in China has made considerable progress, there are still great gaps in agricultural mechanization level compared with developed countries. In order to further narrow the gap between China's agricultural mechanization and developed countries, enhance the scientifi c and technological innovation ability of agricultural machinery, strategic focus of agricultural mechanization have been presented in China. The development strategy of "three steps" is defi ned, that is, the strategic objectives of China's agricultural machinery science and technology innovation and agricultural mechanization development to 2025, 2035 and 2050. Two Development Principles which are full process mechanization and Comprehensive mechanization, and from 1.0 to 4.0 of China Agricultural machinery are emphasized in China.
Simulation and Numerical Analysis of Energy-and-Ecological Compatibility of Indoor Plant Lighting
Authors: Rakutko S. A. , Rakutko E. N.
Published: July 2019

To develop the theory and practice of operation procedures in a greenhouse, a mathematical model of indoor plant lighting is required. (Research purpose) Development of a simulation and analysis technique of energy-and-ecological compatibility of indoor plant lighting. (Materials and methods) The authors experimentally verifi ed the proposed technique for the indoor plant lighting of tomato seedlings grown under laboratory conditions with controlled environmental parameters. An irradiator consisting of a LED matrix with secondary optics and a driver was used. The photoperiod amounted to 16 hours. The experiment was completed for 46 days. The technique includes an analysis of the energy conversion effi ciency at various stages in the blocks of the artifi cial bioenergy system of indoor plant lighting (ABES): a source of electrical power; a radiation source; an optical part; spatial fl ow distribution; surface fl ow distribution; and a plant. The authors proposed formulas for calculating the energy consumption of each ABES unit. It was revealed that for the estimated values of the energy consumption of ABES blocks taken according to expert estimates, the total energy consumption accounts for 0.32-2.27 megajoule per one gramme of wet weight of a plant, i.e. diff ers by almost an order of magnitude, depending on the specifi c implementation of the lighting technology. It is shown that optimization cannot be limited by consistent selection of an option with the lowest value of energy consumption at each stage, but requires fi nding the optimal route on the graph of options. (Results and discussion) For the experimental conditions, the total energy consumption of ABES was 3.77 megajoule per one gramme of the wet weight of a plant. The low effi ciency was caused by the unsatisfactory effi ciency of the LED matrix and the low productivity of the plant photosynthesis. (Conclusions) The developed technique for modeling and analyzing the energy-and-ecological compatibility of indoor plant lighting allowed assessing possible energy saving at each stage of energy and substance conversion in indoor plant lighting. Theoretically, possible reduction of losses in the source of electrical power is 22 percent, in the optical part – 14 percent; in spatial fl ow distribution – 16 percent; in surface fl ow distribution – 10 percent. Possible increasing of the lighting source effi ciency depends on the achieved level of technology, which currently provides an output of 2.5 micromole per joule and more. To increase the productivity of indoor plant lighting, it is necessary to precisely match the parameters of the lighting mode and the requirements of plants.
Chronic Lymphocytic Leukemia Presenting as Irritative Lower Urinary Tract Symptoms and Non-Visible Hematuria: An Atypical Urology Presentation
Authors: Iqbal Muhammad , Jameel Basharat
Published: July 2019

Chronic lymphocytic leukemia (CLL) is an uncommon hematological disease affecting people with recurring infection and is associated with increased risk of progression to high-risk cancer. Bladder CLL is a rare disease hence prognosis and best treatment option is not clearly understood. CLL commonly affects middle-aged women. It presents as abdominal pain, urinary difficulty, fatigue and general symptoms like fever, weight loss and loss of appetite. Chemotherapy, surgery, and radiation is the mainstay of treatment. Prognosis depends on multiple factors including subtype, stage of lymphoma, the progression of the condition, response to treatment, and overall health of the patient. The risk of recurrence and progression to other cancer is very high in bladder CLL which necessitates a strict follow-up protocol. We present a case of an 87-years-old patient presenting with persistent non-visible hematuria and storage lower urinary tract symptoms. Hematuria workup leads to the diagnosis of CLL. Hematology multi-disciplinary team recommended follow up.
Pengaruh Rizobakteria Pemacu Tumbuh dan Toleran Kekeringan serta Kelimpahan dan Akitvitas Mikroba Tanah terhadap Tanaman Jagung (Zea mays L.)
Authors: KAPLI Hari , WAHYUDI Aris Tri , HUSEN Edi
Published: July 2019

Agricultural land in Indonesia was largely dominated by untapped potential land, almost of that potential land is dry land. Maize (Zea mays L.) is one of the staple crops that are known could be cultivated on dry land. Rizosphere has been known to containmicroorganisms that can improve the plant growth. In the previously study, we have screenedin vitro of rhizobacteria (6 isolates of Pseudomonas sp CRB and 7 isolates of Bacillus sp CR) as growth promoter of maize and drought tolerant. A total of 6 rhizobacterial formula were further applied in vivo in greenhouse to promote the growth of maize. In planta test on maize showed that formula CRB 19 and F3 (CR 83 + CRB 10) were the best formula that could enhance plant growth parameters under drought stress conditions. After that abundance and activities of microbe were analyzed by enumeration of total fungus, bacteria and actinomycetes, dehidrogease test, soil respiration test dan C-microbe test and those tests showed that formula CRB 19 and F3 (CR 83 + CRB 10) were the best formula.These formula could be recommended as inoculants of maize planted in dry land agriculture.

 

Keywords : drought tolerant,formulation, growth promoter, maize, rhizobacteria
Internal auditing’s organization and relationship to other governance functions
Authors: Eulerich Marc , Lenz Rainer
Published: July 2019

This study analyzes the integration of the internal audit function (IAF) into the organizational governance structure of nine different organizations and identifies best practices and organizational differences to improve the overall governance quality from the perspective of IAFs. The results of this qualitative study are based on 26 semi-structured interviews, which were conducted with Chief Auditing Executives and Internal Auditors of six listed companies and three organizations from the public/governmental sector. This study highlights factors to improve the relationship between the IAF and other assurance providers, such as the board of directors, the supervisory board in the two-tier-system, the audit committee, risk management or the external auditor. Based on the results, different common practices regarding potential ways of organizing and integrating the internal audit function into organizational governance are identified. The results contribute to the existing literature through a unique inside-view and extend the prior discussion about the benefits and challenges of internal auditors in different organizational (e.g. Roussy, 2015; Roussy & Perron, 2018). Nevertheless, the typical challenges of qualitative research can be found. All best practices provide an adequate benchmark, and support practitioners as well as scholars to better understand the current best practices of effectively working internal audit function. The study gives additional insights to the growing body of literature about the IAF and uses unique data from practitioners
Leaching kinetics of Cs+ and Co2+ under dynamic conditions
Authors: Dimovic Slavko , Nikezic Dusan , Sljivic-Ivanovic Marija , Jelic Ivana , Stanic Vojislav , Radenkovic Mirjana , Loncar Boris
Published: July 2019

The possibility of retaining Cs+ and Co2+ bound by immobilization processes in the cement matrix is defined as the subject of its investigation: the cement matrix formulation, the water/cement ratio, the amount of waste, and the porosity of such a structure. Implementing the standard leaching method by Hespe the possibility of comparing different authors' results was achieved. Diffusion and semi-empirical model were used to investigate the transport phenomenon in order to predict the leaching level for a long period of time. Leaching of Co2+ and Cs+ ions under dynamic conditions immobilized in the cement matrix dynamic conditions decreases with the increase of the sludge content, regarding porosity increase. The effects of the diffusion and surface washing are equalized, and the contribution of the matrix dissolution to the Cs+ and Co2+ transport in the cement porous media increases, on average, for one order of magnitude. The semi-empirical model gives a better approximation for Co2+ and Cs+ leaching process for the duration of the experiment while both models significantly approximate leaching results in dynamic conditions.
Lung Cancer–Related Mortality With Inhaled Insulin or a Comparator: Follow-Up Study of patients previously enrolled in Exubera Controlled Clinical Trials (FUSE) Final Results
Authors: Gatto Nicolle M. , Koralek Daniel O. , Bracken Michael B. , Duggan William T. , Lem Joanna , Klioze Sol , Koch Gary G. , Wise Robert A. , Cohen Roger B. , Jackson Neville C.
Published: July 2019

OBJECTIVE

The Follow-Up Study of patients previously enrolled in Exubera controlled clinical trials (FUSE) was designed to evaluate whether patients previously treated with Exubera (EXU; insulin human [rDNA origin], inhaled powder) in controlled clinical trials died because of incident primary lung cancer at a substantially higher rate than patients treated with a comparator.

RESEARCH DESIGN AND METHODS

FUSE is a hybrid, randomized, controlled trial/cohort study including participants of 17 prior EXU clinical trials. Pooled patient data from these trials were used, and the subset of patients enrolled in the follow-up cohort study was followed prospectively for 2 years in order to evaluate the incidence of fatal and nonfatal primary lung cancers and all-cause mortality.

RESULTS

There were 24,409 person-years (PY) of observation among 7,439 trial patients, with 4,017 PY (16.5%) from the period after the trials but before the prospective follow-up and 5,299 PY (21.7%) from the prospective follow-up. Just over half of the 2,631 patients (51.6%) in the prospective follow-up were randomized to EXU in the original trial. The incidence density ratio was 2.8 (95% CI 0.5, 28.5) for lung cancer–related mortality and 3.7 (95% CI 1.0, 20.7) for incident primary lung cancer. The hazard ratio for all-cause mortality was 0.81 (95% CI 0.60, 1.10).

CONCLUSIONS

These data cannot exclude an increased risk of lung cancer–related mortality associated with EXU use. If real, the absolute increased risk of lung cancer–related mortality was small (0.48 cases per 1,000 PY). For all-cause mortality—the most reliably measured end point with the clearest interpretation—EXU users did not experience an excess all-cause death rate (relative or absolute) compared with users of other diabetes treatments over the study period.
Thermal model based simulation of nanosecond pulsed laser irradiation of Ti6Al4V alloy
Authors: Sinha Sucharita
Published: July 2019

A thermal model based simulation of nanosecond laser irradiation of a Ti6Al4V alloy has been described. Material ablation rates per laser pulse for a laser fluence of up to 15 J/cm2 experimentally measured by the author have shown good agreement with results of the model calculations, duly validating the theoretical approach. Calculated ablation threshold is also in agreement with the experimental data on Ti6Al4V. Calculated maximum temperature reached by a laser irradiated Ti6Al4V target has been compared with an estimated thermodynamic critical temperature for titanium, indicating that for laser fluence below 20 J/cm2 target ablation occurred largely through normal boiling and vaporization. Following this, a simulation based approach allows selection of optimum laser parameters successfully avoiding the onset of explosive boiling in the case of Ti6Al4V targets. Maintaining laser fluence close to the ablation threshold ensures surface texturing of Ti6Al4V with minimum associated surface damage.
«Cartografía del limbo. Devenires literarios de La Habana a Buenos Aires», de Ángeles Mateo del Pino y Nieves Pascual Soler (eds.)
Authors: Romero Morales Yasmina
Published: July 2019

Reseña del libro de Ángeles Mateo del Pino y Nieves Pascual Soler (eds.), Cartografía del limbo. Devenires literarios de La Habana a Buenos Aires (Madrid, Editorial Verbum, 2017).