bluuebunny/crossref_metadata_2025 huggingface dataset:
Assessment of the representation of Antarctic Bottom Water properties in the ECCO2 reanalysis
Authors: Azaneu M. , Kerr R. , Mata M. M.
Published: November 2014

Abstract. We analyzed the ability of the Estimating the Circulation and Climate of the Ocean – Phase II (ECCO2) reanalysis to represent the hydrographic properties and variability of Antarctic Bottom Water (AABW) in the Southern Ocean. We used a 20-year (1992–2011) observational database to perform comparisons of hydrographic properties and reanalysis output for the same time period. Four case studies based on current meter data and the AABW volume transport estimates previously reported in the literature were also evaluated. The opening and maintenance of an oceanic polynya in the Weddell Sea sector is observed after 2004 in the reanalysis product. Moreover, intense deep water production due to deep convection occurs, which leads to a scenario in which the Weddell Sea is flooded with AABW. For this reason, our analyses focused on the period that was identified as more reliable (1992–2004). The main Southern Ocean oceanographic features, as well as the characteristic shape of the regional potential temperature–salinity (θ–S) diagrams, are coincident with observations. However, the reanalysis output produces surface waters that are generally denser than observations due to the reproduction of waters that are generally saltier than expected, which probably resulted from the strong seasonality of sea ice concentrations. Bottom waters are warmer and less dense, while intermediate waters are statistically closest to the observations. The differences in bottom water properties are partially due to the inability of the reanalysis to properly reproduce the formation and export of dense waters from the shelf and the consequent absence of the densest AABW variety for most of the analyzed period. Despite differences in the absolute values, the upper AABW limit (γn ≥ 28.27 kg m−3) and AABW occupied area estimates are coincident with the observations in the World Ocean Circulation Experiment (WOCE) repeat sections SR2 and SR4. Moreover, the AABW volume export and current velocity variability are correlated with the observed time series in the most important region of dense water export (i.e., the Weddell Sea). Despite the consistency in terms of variability, the absolute volume transport and velocity estimates are underrepresented in all cases.
Biofeedback and Integrative Medicine in the Pain Clinic Setting
Authors: Willmarth Eric , Davis Fred , Fitzgerald Kevin
Published: November 2014

Formal pain management clinics have now existed for more than 30 years and from the beginning have incorporated integrative approaches to assist patients suffering from chronic pain conditions. This article will describe the development of these programs and the role that biofeedback and other psychosocial interventions have played in this development. Case vignettes and interviews are used to demonstrate the value of integrating biofeedback and other integrative health practices into a formal pain management practice.
Fall 2014 Special Issue: The Integration of Biofeedback and Neurofeedback into Comprehensive Treatment Programs
Authors: Moss Donald
Published: November 2014

The photo on the cover of this special issue shows multidisciplinary treatment at the Cleveland Clinic Children's Hospital for Rehabilitation. A physical therapist is guiding a patient through a stretching maneuver, while the biofeedback practitioner monitors and supports the patient's self-regulation using HRV biofeedback. (Our thanks to the Cleveland Clinic Children's Hospital for Rehabilitation for the photograph.)
Perioperative and Anesthetic Management of Complete Tracheal Rupture in One Dog and One Cat
Authors: Morath Ute , Gendron Karine , Revés Nuria Vizcaíno , Adami Chiara
Published: November 2014

The authors describe two animals (one dog and one cat) that were presented with severe respiratory distress after trauma. Computerized tomographic imaging under general anesthesia revealed, in both cases, complete tracheal transection. Hypoxic episodes during anesthesia were relieved by keeping the endotracheal tube (ETT) positioned in the cranial part of the transected trachea and by allowing spontaneous breathing. Surgical preparation was performed quickly, and patients were kept in a sternal position to improve ventilation and oxygenation, and were only turned into dorsal recumbency shortly before surgical incision. A sterile ETT was guided into the distal part of the transected trachea by the surgeon, at which point mechanical ventilation was started. Both animals were successfully discharged from hospital a few days after surgery. Rapid and well-coordinated teamwork seemed to contribute to the good outcome. Precise planning and communication between anesthetists, surgeons, and technicians, as well as a quick course of action prior to correct ETT positioning helped to overcome critical phases.
The Successful Use of Negative-Pressure Wound Therapy in Two Cases of Canine Necrotizing Fasciitis
Authors: Maguire Patrick , Azagrar Joseph M. , Carb Allan , Lesser Arnold
Published: November 2014

A 5 mo old female Akita and a 1 yr, 5 mo old male German shorthaired pointer were both evaluated for soft-tissue lesions characterized by rapidly expanding edema, erythema, and pain. Ultrasound was utilized to locate and sample fluid accumulations, and β-hemolytic Streptococcus was isolated from the wounds. Development of systemic symptoms including fever, tachycardia, and tachypnea as well as a lack of response to medical management prompted surgical intervention in both cases. During surgical exploration and debridement, disruption of intermuscular tissue planes was appreciated and necrotizing fasciitis (NF) was suspected. Negative-pressure wound therapy systems utilizing 120 mm Hg of continual negative pressure were applied to wounds for 5 and 4 days for the Akita and German shorthaired pointer, respectively. Resolution of infection was achieved and although the lesions were associated with limbs, amputation was avoided. In both cases, the results of histopathology were consistent with NF. NF is recognized as a rapidly progressive infection associated with high rates of morbidity and mortality. Timely use of negative-pressure wound therapy appears to be a viable management tool to accompany surgical debridement, appropriate antibiotics, and analgesics.
Efecto de la intensidad de corte y actividad fotosintética en el crecimiento de grama (Paspalum notatum Flüggé) en el trópico seco centroamericano (Mesas de Moropotente, Nicaragua)
Authors: Velásquez Meza Karen Elizabeth , Bartolomé Fillelab Jordi , López Benavideza Kenny
Published: November 2014

El trópico seco Centroamericano es un hábitat que está en peligro, y parte de él son las pasturas naturalizadas que cubren la mayor parte de las áreas, representadas en un 46% del total (18.4 millones de hectáreas), siendo uno de los usos de la tierra más importantes (Kaimowitz D.1996) de pastoreo y son la base de la producción bovina en el ámbito regional. El objetivo de este trabajo es determinar el efecto de diferentes intensidades de corte y la actividad fotosintética, en el crecimiento del Paspalum notatum Flüggé. Teniendo como resultados que la intensidad de corte que produce mayor crecimiento del Paspalum notatum es la intensidad media, mostrando así que la frecuencia e intensidad de corte y la radiación fotosintética, se ve reflejado en el crecimiento del mismo. DOI: http://dx.doi.org/10.5377/farem.v0i11.1603 Revista Científica de FAREM-Estelí No.11 2014: 39-46
Evaluación del desarrollo y crecimiento de Enterolobium cyclocarpum, Maclura tinctoria en condiciones controladas, Estelí -Nicaragua
Authors: Hernández Olivas Mariela Lisbeth , Montalván Calderón Beneyda Leticia , Flores Briones Ana María , Urrutia Rodríguez Josué Tomas , López Benavides Kenny
Published: November 2014

A pesar de la creciente importancia que tienen los árboles del trópico seco, para la conservación de la biodiversidad, se conoce poco sobre la dinámica de su comportamiento, tales como: su adaptación frente a diferentes cambios del clima. Con el objetivo de aportar al conocimiento de las dinámicas de su comportamiento frente a estos cambios y obtener información sobre las condiciones en las que pueden desarrollarse estas especies. Se evaluó en la Estación Experimental para el estudio del trópico seco “El Limón”, el comportamiento en crecimiento y desarrollo de plántulas de las especies Maclura tinctoria y Enterolobium cyclocarpum; sometidas a diferentes dosis de agua y grados de temperatura, contribuyendo así a su recuperación y conservación.Se utilizó un diseño de bloques completamente al azar, haciendo una adaptación de la investigación realizada por Díaz. E (2010). Los datos obtenidos se analizaron utilizando la prueba de varianza no paramétrica de Kruskal- Wallis. Ninguno de los tratamientos de humedad aplicados en plántulas de Maclura tinctoria mostraron influencia significativa en diámetro al cuello de la raíz y altura, de igual forma ocurrió en altura de E. cyclocarpum, sin embargo en diámetro al cuello de la raíz mostraron diferencias significativas en el tratamiento de Cc más 50%. Las plántulas de ambas especies expuestas a temperatura ambiente (21.7 °C), mostraron diferencia significativa en diámetro al cuello de la raíz; y en altura presentaron diferencia las de M. tinctoria expuestas a 25.7 °C, y en E. cyclocarpum fueron las expuestas a 30 °C. Ambas especies se adaptan a cambios de temperatura y humedad, siendo recomendada en programas de reforestación. DOI: http://dx.doi.org/10.5377/farem.v0i11.1606 Revista Científica de FAREM-Estelí No.11 2014: 69-80
Efectos post – incendio en bosques de pino del trópico seco de Nicaragua
Authors: Velásquez Benavides Luis Miguel , López Benavides Kenny
Published: November 2014

La investigación se realizó en la Reserva Natural Serranías de Dipilto y Jalapa. Con el objetivo de evaluar los efectos post-incendio en la riqueza y cobertura de herbáceas y leñosas, en bosque de pino. Se determinaron tres intensidades de incendio: alta, media, baja y un control (área no incendiada); mediante la cicatriz dejada por el fuego en los fustes de los árboles de pino. Se establecieron parcelas circulares de 314.16 m2, donde se cuantificó la riqueza y cobertura de especies en tres estratos de la vegetación: arbóreo, arbustivo y herbáceo. En la alta intensidad se encontraron 22 especies en total. Mientras que en la media y baja intensidad se registraron de 18 especies. En el área no incendiada, se encontraron 12 especies. Es evidente que la mayor riqueza de especies se observó en la alta intensidad, lo cual se debe a la activación de los mecanismos de rebrote y bancos de semilla. El aumento de la cobertura de especies herbáceas y leñosas es directamente proporcional a las intensidades del incendio, la cual está vinculada a la riqueza de especies. DOI: http://dx.doi.org/10.5377/farem.v0i11.1608 Revista Científica de FAREM-Estelí No.11 2014: 91-101
ABORDAGENS TEÓRICAS SOBRE A SAÚDE DO TRABALHADOR DE ENFERMAGEM: REVISÃO INTEGRATIVA
Authors: Novatzki Forte Elaine Cristina , Trombetta Ana Paula , Pires Denise Elvira Pires , Gelbcke Francine Lima , Lino Murielk Motta
Published: November 2014

Revisão integrativa com o objetivo de identificar as abordagens teóricas referidas por autores de estudos atuais sobre a saúde do trabalhador de enfermagem. A busca das publicações entre 2008 e 2012 ocorreu em três bases de dados, utilizando-se os descritores saúde do trabalhador e enfermagem. A amostra constituiu-se de 18 artigos. Dentre os artigos excluídos, por não conterem a abordagem teórica explicitada, encontraramse estudos quantitativos, estudos transversais e de coorte. Os estudos selecionados possuem características semelhantes, relacionadas à subjetividade do trabalhador e as formas de organização do trabalho. As abordagens teóricas enriquecem a discussão sobre prazer e sofrimento no trabalho de enfermagem, ofertando um leque de possibilidades de interpretação para as situações vivenciadas pelos trabalhadores, e que independentemente da teoria adotada, os estudos corroboram entre si, no sentido de enriquecer o debate acerca da temática, alguns levantando situações emergentes, outros fornecendo subsídios para a melhoria das condições de trabalho.
Nutrient solution requirements of representatives of the Penicillium clavigerum section
Authors: Piskorz B. , Fiema J.
Published: November 2014

It appeared that the species from the Penicillium clavigerum section require for optimum growth a nutrient solotion composed of: 0,2g NaCl; 0,2g MgSO4-7H2O; 0,1g CaCl2; 0,87g KH2PO4; 0,14g K2HPO4; 4,05mg ZnSO4-7H2O;4,43mg MnSO4-4H2O; 0,5mg FeSO4-4H2O, the presence of vitamins from the group B and of organic N being essential.
New locality of Ischnoderma corrugis in Poland
Authors: Gumińska Barbara
Published: November 2014

A new locality of the species Ischnoderma corrugis (Fr.) Domań et Orlicz in Poland is resported. It is the second locality of in this country. The first one was reported by Wojewoda in the Ojców National Park. In1070 the fungus was found in Pieniny National Park. Several specimens were growing at the base of dead fir trees in a beech forest - Fagetum carpaticum.
Rare and new Laboulbeniales from Poland. II
Authors: Majewski Tomasz
Published: November 2014

A new genus Fanniomycea gen. nov., with a typical species Fananiomyces ceratophorus (Whisler) comb. nov., differing from the genus Stigmatomyces by a sympodially branehed antheridial appendage. Stigmatomyces pedunculatus sp. n. on Leptocera sp. and Stigmatomyces trianguliapicalis sp. n. on Parydra fossarum have been described and the first stands of S. hydrelliae Th. and S. scaptomyzae Th. in Europe are given.
Studies on the blue-staining fungi of pine wood
Authors: Strzelczyk A. , Lamprecht A.
Published: November 2014

The aim of this was were to examine associations of bule-staining fungi which occur on pine wood to determine the interactions between fungi and to check the suscebility of these fungi to commonly used fungieides. The stron antagonism of members of the Trichoderma genus against the blue-staining fungi was demonstrated, Members of genera Pullularia, Hormiscium and Hormodendrum were strongy inhibited by stains of Trichoderma Ophiostoma strains were less susceptible to inhibition by this antagonist.
Fungi living on halophilic plants. II
Authors: Hołownia Irena
Published: November 2014

Uromyces saliorniae (DC.) de Bary and Uromyces sparsus (Kunze et Schmidt) Lev. are species seldom reported from the territory of Europe. From Poland so far only U. sparsus was reported (Busko): in 1964 it was found on a second site in Mątwy near Inowrocław, Uromyces salicorniae was found for the time in Poland in Kołobrzeg in 1966.
Rare and new Laboulbeniales from Poland. IV
Authors: Majewski Tomasz
Published: November 2014

In the fourth of a series of papers dealing with Laboulbeniales in Poland descriptions of two new species: Autophagomyces falcatus sp.n. on Cryptophagus pilosus and Euphoriomyces octotemni sp.n. on Octotemnus globriculus are given The remaining seven species mentioned in the paper are new for Poland and one of them (Rhachomyces speluncalis) was observed for the first time in Europe.
Mycoflora of the trees and shrubs in the yew reservation Wierzchlas
Authors: Weber-Czerwińska Ewelina
Published: November 2014

The author has collected 50 species of fungi. As a result the full life cycle has been studied in 3 species, 28 species occurred only in the conidial stage and 16 species only in the generative stage.
Contribution to the knowledge of rust fungi in the Lublin region
Authors: Romaszewska-Sałata Joanna
Published: November 2014

Rust Fungi (Uredinales), 138 species, collected during the period 196901972 in the Lublin region are reported inthe paper. The most interesting exemples of the species are: Melamsora euphorbiae-gerardianae Puccinia abrotani, P. aromatica, P. crysanthemi, P. cnici-oleracei, P. mili-effusi, Thecopsora galii and Uromyces pallidus. These fungi have been found only in few places in Poland.
Lichenum - nova species in Insulis Canariensibus inventa - The new species of lichen from Canary Islands
Authors: Bystrek Jan
Published: November 2014

The new species Alectoria glauca Stizbgr. from Canary Island is deseribed.
Mycoflora of the forests near Żegiestów and Muszyna in the Beskid Sądecki Mountains
Authors: Lisiewska Maria , Tortić Milica , Szmid Marian
Published: November 2014

During the mycological course in the second part of September 1974, 151 species of macromycetes were collected. They were found mainly in the associations Tilio-Carpinetum and Luzulo-Fagetum in the Beskid Sądecki Mts. (southern Poland). Some of them are rare and noteworthy.
Plant rotation as a means of controlling wilt disease of Lupinus luteus L. on the basis of mycological investigations
Authors: Truszkowska Wanda
Published: November 2014

Having observed in 1969 an epidemic of Fusarium wilt disease of lupin, the communities of fungi occurring in a given cultivated soil were examined. In the years 1970-72, the numbers of the Fusarium oxysporum f.sp. lupini population were found to change, in the others under the influence of lupin having been cultivated in the following crop rotations : 1) rye, potatoes, oats or 2) rye, maize, oats. Provoking changes in the qualitative and quantitative composition of the fungal populations in cultivated soil by means of different cultivated plants, with the aim of altering the conditions of the pathogen, should be practised in order to protect the lupin crops against Fusariuni wilt disease.
Some notes on rare representatives of the Mucorales
Authors: Zadara Maria
Published: November 2014

4 rare specimens of Mucorales are discussed: Mvcotypha microspora, Syncephalis nodosa, Chaetostylum venustellum and Coemansia thaxteri.
New species of parasitic fungi occurring on mites (Acarina)
Authors: Majewski Tomasz , Wiśniewski Jezry
Published: November 2014

The authors describe three new fungi, external parasites of mites occurring in galleries of bark beetles: Thaxteriola moseri, Acariniola subbasalipunctata and A. basalipunctata. The last two have been included in a new genus Acariniola, differing from other representatives of the group Thaxteriolae by a smaller number of cells constituting the thallus (only two) and a penetration pore separated from the foot.
Attempts to eliminate Oidiodendron minus Barron from the substrate of Agaricus cultures
Authors: Rudnicka-Jezierska Wanda , Rutkowska Ewa
Published: November 2014

Among fungi which destroy Agaricus mycelium Oidiodendron maius Barron turned out to be most dangerous. Several simple experiments aimed at limiting its expansion were performed.
Studies on certain aspects of seed-borne fungi. VI. Fungi associated with different cultivars of wheat (Triticum aestivum L.)
Authors: Pandey K. K.
Published: November 2014

Fungi associated with eight cultivars of wheat have been investigated. Twenty seven species were isolated from external and internal surface of all the wheat (Triticum aestivum L.) cultivars respectively. Out of five dominant and subdominant fungi anly Aspergillus terreus and Alternaria tenuis were able to colonize internally. The culture filtrates of test fungi reduced the germination of all wheat varieties up to different degrees.
A contribution to an investigation of nitrogen metabolism of some thermophilic and thermophilous soil fungi
Authors: Gładoch Maria
Published: November 2014

The author has examined the assimilation of nitrogen on the basis of different sources of nitrogen and the secretion of nitrite to the substrate by some soil fungi. The following species of thermophilic and thermophilous fungi have been investigated: Malbranchea pulchella Saccardo et Penzig var. sulfurea Miehe, Humicola lanuginosa (Griffon et Maublanc) Bunce. Sporotrichum thermophile Apinis, Thielavia sepedonium Emmons, Paecilomyces varioti Bainier, Aspergillus fumigatus Fresenius, A. terreus Thom.
Security Cameras Help Monitor Critical Water Facilities
Authors: Givler Suzanne
Published: November 2014

Protecting drinking water facilities is crucial to emergency preparedness. A pilot program at one utility involved extensive setup but grew over time and successfully monitored activity at remote locations. Staff availability to review footage was limited. However, the versatility and extent of camera coverage support the utility's operational and security readiness for unforeseen events.
A Federated Registration System for Artificial Intelligence in Health
Authors: Pencina Michael J. , McCall Jonathan , Economou-Zavlanos Nicoleta J.
Published: August 2024

This Viewpoint discusses a suggested framework of local registries to record and track all health artificial intelligence technologies used in clinical care, with the goal of providing transparency on these technologies and helping speed adoption while also protecting patient well-being.
Extent of Drug Patents With Terminal Disclaimers and Obviousness-Type Double Patenting Rejections
Authors: Tu S. Sean , Kesselheim Aaron S. , Chao Bernard
Published: August 2024

This study evaluates the frequency of terminal disclaimers filed by drug patent holders to obviate obviousness-type double patenting rejections associated with drug patent thickets.
It Is Time for Medicare to Cover Driving Safety Assessments
Authors: Daffner Kirk R. , O’Connor Margaret
Published: August 2024

This Viewpoint advocates for Medicare coverage of driving assessments for older individuals.
Functional loss of ERBB receptor feedback inhibitor 1 (MIG6) promotes glioblastoma tumorigenesis by aberrant activation of epidermal growth factor receptor (EGFR)
Authors: Yi Sang Ah , Cho Daseul , Kim Sujin , Kim Hyunjin , Choi Myung Kyung , Choi Hee Seong , Shin Sukjin , Yun Sujin , Lim Ahjin , Jeong Jae Kyun , Yoon Da Eun , Cha Hye Ji , Kim Kyoungmi , Han Jeung‐Whan , Cho Hyun‐Soo , Cho Jeonghee
Published: August 2024

Dysregulation of epidermal growth factor receptor (EGFR) is one of the most common mechanisms associated with the pathogenesis of various cancers. Mitogen‐inducible gene 6 [MIG6; also known as ERBB receptor feedback inhibitor 1 (ERRFI1)], identified as a feedback inhibitor of EGFR, negatively regulates EGFR by directly inhibiting its kinase activity and facilitating its internalization, subsequently leading to degradation. Despite its proposed role as an EGFR‐dependent tumor suppressor, the functional consequences and clinical relevance in cancer etiology remain incompletely understood. Here, we identify that the stoichiometric balance between MIG6 and EGFR is crucial in promoting EGFR‐dependent oncogenic growth in various experimental model systems. In addition, a subset of ERRFI1 (the official gene symbol of MIG6) mutations exhibit impaired ability to suppress the enzymatic activation of EGFR at multiple levels. In summary, our data suggest that decreased or loss of MIG6 activity can lead to abnormal activation of EGFR, potentially contributing to cellular transformation. We propose that the mutation status of ERRFI1 and the expression levels of MIG6 can serve as additional biomarkers for guiding EGFR‐targeted cancer therapies, including glioblastoma.
An Intelligent Cockpit Tailored Carpet for Human‐Vehicle Interaction Enhancement and Driving Intention Recognition
Authors: Lu Xiao , Gong Yifei , Zhang Haodong , Tan Haiqiu , Zheng Qiwei , Xu Liang , Jin Tao , Li Long , Zhang Quan , Yue Tao , Xie Shaorong
Published: August 2024

In the realm of intelligent cockpits, the predominant emphasis on enhancing driving safety and comfort through human‐vehicle interaction and driving behavior monitoring has conventionally centered on the upper body of the driver. Regrettably, the wealth of information inherent in the lower half of the driver's body, particularly the feet, tends to be systematically underestimated by researchers. A specialized intelligent carpet tailored for automotive cockpits that integrates sponge‐based triboelectric sensor to monitor driver's foot movement is proposed. The intelligent carpet contains two areas, namely the human‐vehicle interaction sensing area and the driving intention monitoring area. With the human‐vehicle interaction sensing area, the driver can interact with the vehicle through the left foot, resulting in reducing the occupation of visual resources and hand load. Furthermore, the driving intention monitoring area supported by the right foot can effectively identify driver's intentions and driver's behaviors, which are essential to trajectory prediction, optimal path planning, and driving safety. It is demonstrated that an intelligent carpet is potentially useful for human‐vehicle interaction, and transportation optimization and accident prevention.
Pseudohalide Anion Passivation for Aqueous‐Stable Pure Red Perovskite Nanocrystals
Authors: Meng Xian , Chen Jie , Liu Yanxiong , Wang Longjie , Zhou Qian , Ma Xiurong , Kong Chuipeng , Shi Yonggang , Zheng Liyan , Cao Qiue
Published: August 2024

Recently emerging perovskite nanocrystals (PNCs) have drawn considerable attention due to the superior optoelectronic performances. However, the terrible stability of red emissive PNCs (r‐PNCs) limits their broader application in aqueous media. Despite various encapsulation methods are proposed, the preparation of aqueous r‐PNCs with facile operation and excellent durability is still challenging. Herein, aqueous green emissive PNCs (g‐PNCs) by employing water as an external stimulus to treat oleyamine‐capped CsPbBr3 PNCs are synthesized initially, and then aqueous‐stable pure red emissive PNCs by anion‐exchange reaction and subsequently thiocyanate (SCN‐) passivation treatment (SCN‐r‐PNCs) are prepared. The obtained aqueous‐stable SCN‐r‐PNCs display high brightness, outstanding stability, and extended photoluminescence lifetime. Moreover, by combining aqueous r‐PNCs and portable smartphones, a fluorescence chemosensor for the detection of aqueous SCN− ions is constructed, which exhibits simple operation, high sensitivity, high selectivity, low detection limit, and visualized sensing. This work not only provides a new and facile strategy to prepare aqueous‐stable red emissive PNCs, but also further extends the application of red emissive PNCs in aqueous‐based fields.
Trailblazing 3D MOFs Featuring 1,2,4‐Dinitrimino Triazole: Redefining Energetic Materials and Iodine Encapsulation
Authors: Jujam Manojkumar , Rajak Richa , Dharavath Srinivas
Published: August 2024

The quest for high‐performance energetic materials for defense and aerospace has intensified, focusing on balancing energy output and safety. This study presents the synthesis of 3D energetic metal‐organic frameworks (EMOFs) [Na3(DNT)(H2O)]n (Na‐MOF), [K2(DNT)2(H2O)]n (K‐MOF), and [Cs2(DNT)]n (Cs‐MOF) using 1,2,4‐dinitrimino triazole (DNT) through a hydrothermal process. The synthesized EMOFs are characterized using infrared spectroscopy, powder X‐ray diffraction, scanning electron microscopy (SEM), elemental analysis, and thermogravimetric analysis and differential scanning calorimetry, and structures confirmed via single‐crystal X‐ray diffraction, revealing 3D frameworks with crystal densities of 2.15, 2.16, and 2.86 g cm−3, respectively. Among them, Na‐MOF exhibits excellent detonation performance (VOD = 8900 m s−1, DP = 26.21 GPa), high thermal stability (Td = 369 °C), and insensitivity to impact and friction (IS = 40 J, FS = 360 N). K‐MOF displays balanced energetic and mechanical properties, while Cs‐MOF, though moderate in energetic performance, shows significant potential in pyrotechnic applications, producing a bright red flame. Intermolecular interactions are analyzed through Hirshfeld surface, 2D fingerprint, and SEM analyses, enhancing the understanding of particle size and morphology. Na‐MOF also demonstrates high iodine encapsulation capacity, positioning it as a potential replacement for traditional materials like RDX and heat‐resistant explosives such as HNS, with comparability to PYX.
Fusible and Radiopaque Microspheres for Embolization
Authors: Li Jing , Xu Jingyi , Wang Yunpeng , Chen Yue , Ding Yuanyuan , Gao Wenxia , Tan Yexiong , Ge Naijian , Chen Yibin , Ge Shennian , Yang Qi , He Bin , Ye Xueting
Published: August 2024

In this work, fusible microspheres loaded with radiopaque agents as an embolic agent for transcatheter arterial embolization (TAE) are developed. A poly(ethylene glycol) (PEG) and poly(ε‐caprolactone) (PCL) multi‐block copolymer basing polyurethane (PCEU) is synthesized and fabricated into blank microspheres (BMs). The microspheres are elastic in compression test. A clinical contrast agent lipiodol is encapsulated in the microspheres to receive fusible radiopaque microspheres (FRMs). The sizes of FRMs are uniform and range from 142.2 to 343.1 µm. The encapsulated lipiodol acts as the plasticizer to reduce the melting temperature point (Tm) of PECU microspheres, thus, leading to the fusion of microspheres to exhibit efficient embolization in vivo. The performance of FRMs is carried out on a rabbit ear embolization model. Serious ischemic necrosis is observed and the radiopacity of FRMs sustains much longer time than that of commercial contrast agent Loversol in vivo. The fusible and radiopaque microsphere is promising to be developed as an exciting embolic agent.
Transforming Commercial Polymers into Tough yet Switchable Adhesives by Trident Photoswitch Molecule Doping: Break Adhesion‐Switchability Paradox
Authors: Lin Ziwei , Feng Jie , Fang Long , Zhang Yang , Ran Qishan , Zhu Qikai , Yu Dingshan
Published: August 2024

Here, a trident molecule doping strategy is introduced to overcome both cohesion‐adhesion trade‐off and adhesion‐switchability conflict, transforming commercial polymers into tough yet photo‐switchable adhesives. The strategy involves initial rational design of new trident photoswitch molecules namely TAzo‐3 featuring azobenzene and hydroxy‐terminated alkyl chains involved rigid‐soft tri‐branch structure, and subsequent doping into commercial polycaprolactone (PCL) via simple blending. Unique design enables TAzo‐3 as a versatile dopant, not only regulating the internal and external supramolecular interaction to balance cohesion and interface adhesion for tough bonding, but also affording marked photothermal effect to facilitate rapid adhesive melting for great photo‐switchability. Thus, the optimal TAzo‐3‐doped PCL (TAzo‐3@P) displays markedly‐improved bonding performance on diverse substrates compared to linear azobenzene‐doped PCL and pure PCL. Impressively, TAzo‐3@P on polymethyl methacrylate (PMMA) attains large room‐temperature adhesion strength of 6.7 MPa – surpassing most reported adhesives and many commercial adhesives on PMMA, along with easy photo‐induced detachment with remarkable switch ratio of 2.09 × 105. Besides, TAzo‐3@P can also act as “permanent” adhesives for only adhesion, demonstrating excellent multi‐reusability, anti‐freezing and waterproof ability. Mechanism studies unveil that the switchable adhesion is closely linked with the dopant molecule structure while rigid‐soft coupled trident structures and hydroxy‐terminated alkyl chains are key factors.
Zero‐Biased Bionic Fingertip E‐Skin with Multimodal Tactile Perception and Artificial Intelligence for Augmented Touch Awareness
Authors: Guo Xinge , Sun Zhongda , Zhu Yao , Lee Chengkuo
Published: August 2024

Electronic skins (E‐Skins) are crucial for future robotics and wearable devices to interact with and perceive the real world. Prior research faces challenges in achieving comprehensive tactile perception and versatile functionality while keeping system simplicity for lack of multimodal sensing capability in a single sensor. Two kinds of tactile sensors, transient voltage artificial neuron (TVAN) and sustained potential artificial neuron (SPAN), featuring self‐generated zero‐biased signals are developed to realize synergistic sensing of multimodal information (vibration, material, texture, pressure, and temperature) in a single device instead of complex sensor arrays. Simultaneously, machine learning with feature fusion is applied to fully decode their output information and compensate for the inevitable instability of applied force, speed, etc, in real applications. Integrating TVAN and SPAN, the formed E‐Skin achieves holistic touch awareness in only a single unit. It can thoroughly perceive an object through a simple touch without strictly controlled testing conditions, realize the capability to discern surface roughness from 0.8 to 1600 µm, hardness from 6HA to 85HD, and correctly distinguish 16 objects with temperature variance from 0 to 80 °C. The E‐skin also features a simple and scalable fabrication process, which can be integrated into various devices for broad applications.
Local Dipole Modulation Toward High Fill Factor in Organic Solar Cells
Authors: Chen Zhihao , Xiao Yang , Yao Huifeng , Ren Junzhen , Zhang Tao , Qiao Jiawei , Zhu Shangqian , Lin Richen , Hao Xiaotao , Hou Jianhui
Published: August 2024

Dipole moment arrangement in organic semiconductors plays a critical role in affecting the intermolecular packing, determining optoelectronic properties and device performance. Here, to get the desired fill factor (FF) values in organic solar cells (OSCs), the local dipole of non‐fullerene acceptors (NFAs) is modulated by changing the molecular asymmetries. Two NFAs, AA‐1 and AA‐2 are designed and synthesized, which have different substitutions of alkyl and alkoxyl groups. The unidirectional asymmetry in AA‐2 creates distinct local dipoles, while the bidirectional asymmetry in AA‐1 mitigates dipole variation. Despite the minimal impact on monomolecular properties, the local dipole moment significantly influences terminal group packing modes in the film state. This, in turn, enhances the relative dielectric constant, prolongs exciton lifetime, and reduces sub‐bandgap defect states. Consequently, PBDB‐TF:AA‐2‐based OSCs achieve an exceptional FF of 0.830 and a power conversion efficiency (PCE) of 18.3%, with a ternary device reaching a PCE of 19.3%. This work highlights the potential of dipole modulation in material design to get ideal FF values for high‐performance OSCs.
Interaction of a caffeine overdose with clinical doses of contraceptive ethinyl estradiol in a young woman
Authors: Adachi Koichiro , Murata Maki , Inada Akiyoshi , Morimoto Takeyori , Shimizu Makiko , Beppu Satoru , Yamazaki Hiroshi
Published: August 2024

Aim

The overdose of caffeine, a cytochrome P450 1A2 probe, in young women has become a problem. The aim of this study was to evaluate possible drug interactions between intentionally overdosed caffeine (12 g) and oral contraceptive doses of ethinyl estradiol prescribed to a young woman in a suicide attempt.

Methods

The serum concentrations of caffeine in the patient and the time‐dependent ethinyl estradiol inhibition of caffeine oxidation in vitro were evaluated.

Results

The serum concentration of caffeine 4 h after overdose was 136 μg/mL; from the data obtained between 4 and 28 h after overdose, the half‐life was estimated to be 33 h, which is many times larger than the normal value. Prescribed ethinyl estradiol prolonged caffeine elimination in vivo and inhibited paraxanthine formation, as evidenced by the low serum concentrations. In human liver microsomes, ethinyl estradiol (50 nM) inhibited half of caffeine N3‐demethylation. Pre‐incubation of human liver microsomes with ethinyl estradiol resulted in a powerful time‐dependent inhibitory effect on caffeine N3‐demethylation in human liver microsomes.

Conclusion

These results suggest that a prescription history of contraceptives at clinical doses may have a strong effect on the pharmacokinetics of overdosed caffeine in young women, resulting in dangerous drug interactions.
Recent Advances in Geometric Phase Metasurfaces: Principles and Applications
Authors: Faraz Faizan , Tian Jie , Abbasi Taufeeq Ur Rehman , Zhu Weiren
Published: August 2024

The concept of geometric phase traversing numerous domains in physics and has been a continuous source of fascination and inspiration for researchers. Despite the extensive research surrounding geometric phase from decades, advances in technology continue to yield novel theories, innovative devices, and captivating applications, extending even to the realm of subwavelength scales. This review article provides a comprehensive exploration of geometric phase metasurfaces, delving into their design principles and categorizing them based on materials properties. In addition, multi‐fold and reconfigurable metasurfaces based on geometric principle are further explored with their unique capabilities and potential impact on a diverse range of applications, including beam steering, lensing, polarization conversion, and holographic imaging. By examining the state‐of‐the‐art in geometric phase metasurfaces, insights are aimed to offer into their current capabilities and limitations. Finally, the prospects and challenges are discussed that lie ahead for this promising field, paving the way for future advancements and innovations.
Fabrication of smart sunlight window using silver vanadate nanorods (β‐AgVO3) and its effect on phytochemical properties of several agricultural species
Authors: Bagiyan Majid , Zahedifar Mostafa , Sadeghi Ehsan , Dehghani Bidgoli Reza
Published: August 2024

Silver vanadate nanorods were synthesized for the first time via co‐precipitation, followed by ambient drying. X‐ray diffraction (XRD), energy dispersive X‐ray (EDX), and scanning electron microscope (SEM) analyses were utilized to investigate the structure and morphology of the nanorods. The results of these analyses confirmed the fabrication of silver vanadate nanorods. Then, to check the ability of these nanostructures to be used in the smart window, their optical properties, including the visible–ultraviolet absorption spectrum and photoluminescence (PL), were studied. The results showed that this nanostructure has maximum absorption and emission at wavelengths of 530 and 670 nm, respectively. Next, the new smart window was made with a layer of silver vanadate nanorods, and wheat, barley, millet, and beet were placed under this smart window to perform phytochemical tests. It was observed that silver vanadate nanorods could shift the green wavelength to higher wavelengths and efficiently improve the phytochemical properties of the mentioned plants.
Construction of carbon quantum dots/riboflavin fluorescent probe and its application in the detection of ciprofloxacin
Authors: Fu Mingjun , Lan Yuwei , Bao Wenbin , Li Guowei , Lu Haiqin , Zhou Liya , Lan Huan , Mo Xixian
Published: August 2024

The research outlined a novel approach for creating a sensitive and efficient ratio fluorescent probe for ciprofloxacin (CIP) detection. The method used the biomass materials passionfruit shell and diethylenetriamine as carbon and nitrogen sources, respectively, to prepare blue fluorescent carbon quantum dots (b‐CQDs) with an average size of 3.29 nm and a quantum yield of 19.6% by a hydrothermal method. The newly designed b‐CQDs/riboflavin ratio fluorescent probe demonstrates a distinct advantage for CIP monitoring, exhibiting a marked increase in fluorescence intensity at 445 nm upon interaction with CIP, while maintaining a stable intensity at 510 nm. In the water system, the I445 nm/I510 nm ratio of the fluorescent probe showed a significant linear relationship with CIP at the concentrations of 0–250 μmol·L−1, and the probe boasts a low detection limit of 0.86 μmol·L−1. The outstanding selectivity, broad detection range, low detection limits, and high quantum yield of the b‐CQDs highlight their significant potential in the development of advanced sensing probes for efficient detection of ciprofloxacin, offering promising insights for future sensor technology advancements.
The effect of SiO2 crystallization in enhancing the luminescence of Dy3+‐Sm3+ co‐doped glass ceramics for cool white light application
Authors: Monisha M. , Saravanan M. , Mazumder N. , Sayyed M. I. , Rashad M. , Kamath S. D.
Published: August 2024

The present work investigates the structural and luminescence behaviour of Dy3+‐Sm3+ co‐doped glass ceramics obtained through heat treatment of precursor glasses. The growth of SiO2 polycrystalline particles and evolution of these crystallites in the glass domain are witnessed via XRD and FESEM study. The presence of network vibrational bands, hydroxyl groups and the increased quantity of bridging oxygens (BOs) in glass ceramics are analysed through FTIR spectroscopy study. The absorption study (UV–Visible–NIR) showed the possible electronic transitions of Dy3+ and Sm3+ ions. The red shift in the absorption band edges and the lower bandgap values are obtained as a result of improved heat treatment in glass ceramics. Emission studies show the enhanced luminescence intensity of glass ceramics under 350 and 402 nm excitations. Decay measurement of glass ceramics showed the improved lifetimes of Dy3+ and Sm3+ ions to have appeared in microseconds (×10−6 s). The colour characteristics of glass ceramics analysed using CIE colour chromaticity diagram and correlated colour temperature (CCT) values suggest the neutral to cool white light emissions. Therefore, prepared glass ceramics with SiO2 polycrystalline phase are considered to be suitable materials in cool white LEDs applications.
Machine learning methods as auxiliary tool for effective mathematics teaching
Authors: Milićević Marina , Marinović Budimirka , Jeftić Ljerka
Published: August 2024

Seeing mathematics teaching as a very demanding and responsible process while having in mind the importance of mathematical knowledge for students of technical faculties, this paper aims to present heuristics for student classification according to their predicted mathematical success. Over the last few decades, the process of informatization of universities has resulted in new challenges universities are faced with. Due to the widespread use of educational databases, which opens new possibilities for educational data mining and analyses, machine learning algorithms have become a very popular tool for predicting students' academic performance. The decision tree algorithm is used in this paper for the classification and prediction of students' mathematical performance and it is trained on the data collected from the educational information system. The experimental results show that the model accuracy is 72% with an error rate of 0.28. The implementation of the Decision Tree Model to predict whether a student will pass, fail or be conditional in mathematical courses is important for both teachers and students, as well as for universities. Students' performance is one of the major keys in evaluating the quality of the teaching process, but also for evaluating the overall success of the university itself. As mathematics is considered a basic and important discipline, it is clear why predicting students' mathematical achievement is crucial for all levels of university organization.
Mechanical thrombectomy using neurovascular catheter from radial artery during acute myocardial infarction: A case report
Authors: Cacia Michele , Nesta Cristina , Pascale Vittorio , Vatrano Marco , Galiano Leone Giulia , De Luca Emilia , Ferraro Alessandro , Ciconte Vincenzo Antonio
Published: August 2024

Key Clinical Message

Coronary occlusion due to large thrombus is frequently encountered during ST‐elevation myocardial infarction (STEMI). Despite guidelines discourage this practice, often thrombus aspiration is necessary to reduce thrombotic burden and to prevent embolization. We report a case of mechanical thrombectomy with a Neurovascular Catheter from radial artery during inferior STEMI.
Lumbosacral epidural lymphoma: A case report and comprehensive review of literature
Authors: Eslami Masoud , Aledavoud Ali , Ilaghi Mehran , Ferdousie Vahid Tavakolian , Reihani‐Kermani Hamed
Published: August 2024

Key Clinical Message

Epidural lymphoma of the lumbosacral region is a rare condition that manifests with back pain and nonspecific neurological symptoms. Our case which was diagnosed with diffuse large B‐cell lymphoma, highlights the importance of recognizing early lymphoma symptoms to enable timely treatment and improved outcomes.

Lymphoma rarely presents in the lumbosacral epidural space. Initial presentations of lymphoma are of paramount importance in the timely diagnosis and management of the disease. We report a 42‐year‐old woman presented with 4 years of low back pain and progressive right lower extremity paresthesia. Lumbar MRI revealed an epidural soft tissue lesion compressing nerves at L4 to the coccyx. Laminectomy and tumor resection were performed. Pathologic findings confirmed diffuse large B‐cell lymphoma. We systematically reviewed the literature on lymphomas with lumbar epidural space involvement reported since 1990. Twenty‐four cases from 19 reports were identified. The mean age of lumbar epidural lymphoma cases was 39.5 ± 17.8 years, and 72% were male. The most common subtype was diffuse large B‐cell lymphoma, and common presentations included back pain, lower extremity neurological deficits, and bowel/bladder dysfunction. Overall, lymphomas presenting in the spine can pose diagnostic challenges owing to nonspecific initial symptoms. Our case highlights the importance of recognizing early lymphoma symptoms to enable timely treatment and improved outcomes.
Cationic or Neutral: Dependence of Photophysical Properties of Bis‐Alkynylphosphonium Pt(II) Complexes on Ancillary Ligand
Authors: Paderina Aleksandra , Sizova Anastasia , Grachova Elena
Published: August 2024

A series of D‐π‐A alkynylphosphonium salts with different linker between donor and acceptor groups was used to synthesize two series of trans‐bis‐alkynylphosphonium Pt(II) complexes with different ancillary ligands (triphenylphosphine, P series, and cyanide, CN series). The nature of the ancillary ligand manages the overall charge and emission properties of the complexes obtained. In addition, the variation of the linker in alkynylphosphonium ligands allows fine‐tuning the luminescence wavelength. Dicationic series P is unstable in solution under UV excitation, whereas in the solid state, these complexes are the first example of phosphorescent trans‐phosphine‐bis‐alkynyl Pt(II) compounds. Neutral series CN demonstrates bright emission in solution, including dual emission for 2CN complex with biphenyl linker in alkynylphosphonium ligand. However, in the solid state for the CN series drastic decrease in the emission quantum yield compared to the P series was observed. DFT calculations reveal the complicated emission nature for the both P and CN series with various contributions of 3ILCT, 3LLCT and 3MLCT states. However, in the naphthyl‐containing derivatives 3P and 3CN, the dominating 3LC character with some admixture of CT states is postulated.
Hereditary sensory autonomic neuropathy type VI in the age of genetic testing
Authors: Peringassery Sateesh Lekshmi , Chitamanni Pavani , Akinsanmi Danielle , Ghosh Suman , Pavlakis Steven G. , Reznikov Alexandra
Published: August 2024

Background

Hereditary sensory and autonomic neuropathy type VI (HSAN VI) is a rare recessive genetic disorder caused by mutations in the human dystonin (DST) gene. We report a novel homozygous alternate transcript mutation in the DST gene causing a severe neonatal form of HSAN VI.

Patient Description

This baby boy was born with severe hypotonia, respiratory distress, dysmorphic features, and bilateral club feet. Imaging, karyotyping, Prader–Willi assay, spinal muscular atrophy genetic panel and myotonic dystrophy genetic panel were all negative. A comprehensive neuropathy panel detected a homozygous pathogenic variant in the DST gene—alternate transcript NM_015546.4:c.1357G>A (p.Trp4525*). Nerve conduction studies revealed mixed axonal and demyelinating sensorimotor neuropathy, suggesting the possibility of motor involvement in severe forms of this rare condition. The infant ultimately developed sepsis and died from cardiorespiratory arrest. Neuropathological findings of focal and mild spinal nerve axonal degeneration were nonspecific.

Conclusion

Collective analysis of these patients would help to further characterize the spectrum of disease pathology and could provide insight into the neurophysiology and neuropathology of this rare condition.