bluuebunny/crossref_metadata_2025 huggingface dataset:
Gestational diabetes mellitus: outcomes of pregnancy and childbirth
Authors:   South Ural State Medical University, Chelyabinsk, Syundyukova E. G. , Medvedev B. I. ,   South Ural State Medical University, Chelyabinsk, Chulkov V. S. ,   South Ural State Medical University, Chelyabinsk, Ryabikina M. G. ,   South Ural State Medical University, Chelyabinsk, Tarasova L. B. ,   South Ural State Medical University, Chelyabinsk, Filippova N. A. ,   South Ural State Medical University, Chelyabinsk, Yakovleva Yu. A. ,   South Ural State Medical University, Chelyabinsk
Published: February 2022

Relevance. Gestational diabetes mellitus remains an important medical and social problem, which is determined by the high frequency of occurrence and the negative impact on the outcomes of pregnancy and the condition of the newborn, as well as the presence of long-term therapeutic consequences for the mother and progeny. The aim of the study was to study the features of the anamnesis, the course of pregnancy and perinatal outcomes in women with gestational diabetes mellitus compensated by diet therapy. Materials and methods. A retrospective study involved 30 pregnant women without carbohydrate metabolism disorders (group 1) and 30 patients with gestational diabetes mellitus compensated by diet therapy. The features of the somatic and obstetric-gynecological anamnesis, the outcomes of pregnancy and childbirth are analyzed. The statistical methods of the study were performed using the SPSS Statistica for Windows 17.0 software packages, the Mann-Whitney U test, Chi-square test, likelihood ratio, linear-linear relationship were used at the significance level of the criterion of 0.05. The results of the study. The somatic history of women with gestational diabetes mellitus is associated with the presence of overweight / obesity (40.0%) and allergic diseases (10.0%), obstetric and gynecological-cases of complicated childbirth (36.7%), often premature (13.3%), as well as cesarean section operations and the birth of low-weight children. Pregnancy against the background of carbohydrate disorders compensated by diet therapy is associated with an increase in the frequency of nausea and vomiting in the early stages (10.0%), edema of pregnant women (30.0%), placenta previa (13.3%), anemia (50.0%), urogenital infection (66.6%), cesarean section operations (40.0%). In newborns from mothers with carbohydrate disorders, an increase in growth-weight indicators was noted against the background of a violation of their functional characteristics. Conclusion. Optimization of the prognosis, early diagnosis and treatment of gestational diabetes mellitus is a necessary strategy to prevent adverse pregnancy outcomes for the mother and offspring.
The role of biochemical markers in predicting the outcome of ischemic stroke
Authors:   Tyumen State Medical University, Tyumen, Kicherova O. A. , Reikhert L. I. ,   Tyumen State Medical University, Tyumen, Skorikova V. G. ,   Regional treatment and rehabilitation center, Tyumen, Semeshko S. A. ,   Medical hospital “Neftyannik”, Tyumen
Published: February 2022

Despite significant advances in the treatment of ischemic stroke, which were achieved due to the implementation of the program to combat stroke, the mortality and disability rates in this pathology continue to remain high. The identification of biochemical markers of the unfavorable clinical course of cerebral infarction is quite urgent, since it can be a useful addition to the optimization of predicting the outcomes of acute cerebrovascular catastrophe and the effectiveness of thrombolytic therapy.
Treating bone pain syndrome of the patients with uncomplicated vertebral compression fractures during II and III stages of rehabilitation treatment
Authors:   Nizhnevartovsk city children’s polyclinic, Nizhnevartovsk, Burmatov N. A. , Sergeev K. S. ,   Tyumen State Medical University, Tyumen, Gerasimov A. A. ,   Ural State Medical University, Ekaterinburg, Kopylov S. A. ,   Omsk State Medical University, Omsk
Published: February 2022

The aim of this prospective study is to improve the results of treating type A1 and A2 uncomplicated vertebral compression fractures using intratissual electric stimulation (ITES) during II and III stages of rehabilitation treatment. Materials and Methods. The study analyses the use of intratissual electric stimulation (ITES) for treating bone pain syndrome of the patients with type A1 and A2 mono and bisegmental spinal fractures (according to Magerl classification) in a distant period. The whole population is 86 patients, aged from 45 to 65. In-patients were treated using vertebral column extension, some physical therapy and medication. The observation period lasted 12-36 months. It is the stage of control observation. The patients who complained of constant and reemerging pain syndrome were treated using intratissual electric stimulation (ITES). Immediate, short- and long-term outcome analysis was carried out. It is the final stage of the treatment. Clinical, neurotic and rehabilitation status of the patients is analized taking into account Sagittal balance parameters, the spinal canal condition and rehabilitation vectors with numerical ratings. The objective pain assessment was performed by measuring skin surface electric potential according to Gerasimov (1991). The quality of life was assessed using Oswestry Disability Index (ODI). Results. The analysis of morphometric characteristics pointed out changes in sacro-pelvic correlation (LSB), flattening of lumbar lordosis, stenosis of the spinal canal, post-traumatic changes and involution in lumbar and thoracic vertebrae. The control stage of the research revealed significant improvement of patients’ sacro-pelvic balance parameters, pain syndrome elimination and the improvement of the quality life. Conclusion. The pathogenetically substantiated method of treating adult or elderly patients with spinal traumas, the use of intratissual electric stimulation at the outpatient rehabilitation stage prove to be effective.
Analysis of regional features affecting the organization and provision of medical care in KHMAO-Ugra
Authors:   Khanty-Mansiysk State Medical Academy, Khanty-Mansiysk, Razumova T. V. , Zuyevskaya T. V. ,   Khanty-Mansiysk State Medical Academy, Khanty-Mansiysk, Pavlov P. I. ,   Regional Clinical Hospital, Khanty-Mansiysk, Zuyevsky V. P. ,   Khanty-Mansiysk State Medical Academy, Khanty-Mansiysk, Sadrieva E. V. ,   Khanty-Mansiysk State Medical Academy, Khanty-Mansiysk, Pryahina E. V. ,   Regional Clinical Hospital, Khanty-Mansiysk
Published: February 2022

Purpose of the study: assessment of the features of the geographical location, climatic conditions, economic development, demographic situation, affecting the organization of medical care in the Khanty-Mansi Autonomous Okrug-Yugra. Materials and research methods: statistical materials from the annual collection “Health of the population of the Khanty-Mansi Autonomous Okrug-Ugra and the activities of medical organizations” and data of statistical reporting on the incidence of the population from the “Medstat” program were used. The analysis used indicators such as population density, the proportion of small peoples of the North, the availability of medical care, the proportion of the able-bodied population, indicators of the economic development of the Khanty-Mansi Autonomous Okrug-Yugra. Results. The conditions for the organization and provision of medical care on the territory of the Khanty-Mansi Autonomous Okrug-Yugra are determined by the geographic location of the area, equated to the regions of the Far North, the difficult climatic conditions that negatively affect human health, a significant proportion of the visiting population, poorly adapted to the conditions of the North, a combination of developed urban agglomerations (with a developed healthcare infrastructure) and sparsely populated areas, a significant length of the territory of the Khanty-Mansi Autonomous Okrug-Yugra, problems of transport infrastructure and low transport accessibility of remote areas.The above determine the need for approaches in planning medical care that are not typical for the constituent entities of the Russian Federation (for example, the territory of the Central Federal District). These approaches require increased costs for organizing a network of medical institutions and resource and staffing of medical care to the population, which is quite feasible taking into account the economic situation of the Khanty-Mansi Autonomous Okrug-Yugra. Conclusion. Factors affecting the organization and provision of medical care, and the health of the population of the Khanty-Mansi Autonomous Okrug-Yugra, should be attributed to the harsh climatic conditions, environmental factors associated with the extraction of minerals (oil and gas). Climatogeographic and social conditions are a risk factor for alcoholization of the population, the presence of natural focal diseases. Features of the economic development of the Khanty-Mansi Autonomous Okrug-Yugra requires increased costs for organizing a network of medical organizations, resource and staffing.
The possibilities of normobaric interval hypoxic training in practical gynecology
Authors:   Tyumen State Medical University, Tyumen, Vinokurova E. A. , Baranov V. N. ,   Industrial University of Tyumen, Tyumen, Petrov D. I. ,   Tyumen State Medical University, Tyumen
Published: February 2022

The article discusses published sources of domestic and foreign studies concerning studies of the possibility of using normobaric interval hypoxic training in gynecological pathology.
Bronchial asthma in obese patients: literature review
Authors:   Tyumen State Medical University, Tyumen, Grakhova M. A. , Troshina I. A. ,   Tyumen State Medical University, Tyumen, Zinkevich M. E. ,   Tyumen State Medical University, Tyumen, Miasnikov M. E. ,   Tyumen State Medical University, Tyumen
Published: February 2022

Bronchial asthma (BA) is a widespread disease affecting up to 339 million people worldwide. Currently, a number of BA phenotypes are distinguished: asthma associated with obesity, allergic, non-allergic, asthma with late onset, and asthma with fixed bronchial obstruction. According to the World Health Organization, more than 30% of the world population is obese. According to GINA, the phenotype “BA with obesity” is characterized by a more severe development of the decease, low level of disease control, resistance to baseline therapy, frequent hospitalizations for exacerbations, and the comorbid pathology in patients. In this connection, personalized approach is required, with individual selection of therapy, which is often not effective enough, which entails the need for further study of the disease development and its pathogenesis factors. To date, the role of obesity in the mechanisms of formation of a more severe development of BA has been actively studied. It has been shown that many other factors such as oxidative stress, changes in vitamin D and periostine levels, changes in airway physiology due to obesity, sleep disorders and genetic predisposition can influence the development and/or exacerbation of dyspnea in obese patients.
Diagnostic value of laboratory tests for predicting the severity of COVID-19
Authors:   Tyumen State Medical University, Tyumen, Matveev I. A. , Matveeva T. A. ,   Regional Clinical Hospital No. 1, Tyumen
Published: February 2022

Aim. The study of laboratory deviations in homeostasis is one of the main ways to control the severity of the course of COVID-19 and its treatment. In this connection, the goal is set: based on a review of literary publications and our own research, to assess the results of various tests in critically ill patients and to determine their diagnostic accuracy in predicting the severity of COVID-19. Materials and methods. Analyzed 35 literary sources of information and the material of our own research on the diagnostic accuracy of tests in determining severe forms of the disease conducted in 46 patients with COVID-19. Results. The results of test studies in severe patients with COVID-19 showed, in most cases, lymphopenia, thrombocytopenia, an increase in CRP and d-dimer, and transaminase activity. Their ambiguity in assessing the severity and prognosis of the disease was noted. Their diagnostic accuracy in determining the prognosis of the development of severe forms of the disease has been relatively rarely studied. The most accurate results in assessing the prognosis of the severity of the course of COVID-19 were obtained in the study of CRP and test associations in various combinations and ratios. Conclusion. Our own study of lymphocytopenia, thrombocytopenia, d-dimer showed their low diagnostic quality in identifying severe patients with COVID-19. The sensitivity, specificity and predictive value of positive results were less than 50%. Exceeding these limits was obtained in the study of CRP, which determines its leading role in assessing the severity of the course of COVID-19. All tests in the studied values, except for CRP, did not have sufficient qualities to determine the severe condition of patients, which does not allow their use for self-testing of a severe course of infection. This requires the study of tests with values significantly higher than the norm. The use of test combinations, as well as their interconnection, made it possible, in a number of cases, with high diagnostic accuracy to predict the severe course of COVID-19, but this direction of studying the control of the course of infection requires further analysis.
The effect of metabolic syndrome on changes in the indicators of trace microelemental status and lipid peroxidation system in patients with psoriasis vulgaris
Authors:   Tyumen State Medical University, Tyumen, Gurbo O. P. , Frolova O. I. ,   Tyumen State Medical University, Tyumen, Kovkova G. Yu. ,   Tyumen State Medical University, Tyumen, Bogomazova M. A. ,   Tyumen State Medical University, Tyumen, Bystritskaya O. D. ,   Center for Vocational Education "ACCENT", Tyumen
Published: February 2022

Aim. To study the effect of metabolic syndrome on changes in the indicators of trace element status and lipid peroxidation system in patients with psoriasis vulgaris. Materials and methods. In the framework of this work, 80 patients were examined with a diagnosis of vulgar psoriasis (group I without metabolic syndrome, group II with metabolic syndrome). The study of the trace element status, the serum content of 25-OH hydroxycalciferol, alpha– tocopherol acetate, as well as the state of the lipid peroxidation system were carried out. Results. in patients with metabolic syndrome, were discovered: a decrease in the indicators of trace element status and vitamins, an increase in the overall oxidative capacity of the blood, an increase in the level of oxidative low-density lipoproteins, as well as a decrease in the overall antioxidant activity of the blood. Conclusion. The obtained data allows to develop recommendations for the management and treatment of patients with vulgar psoriasis by correcting the microelement status and vitamins, which will reduce the influence of metabolic syndrome on the course of the psoriatic process at an early stage.
In silico pharmacokinetics and toxic properties of peptide with anticoagulant activity isolated from peloid
Authors:   Tyumen State Medical University, Tyumen, Kalinin E. P.
Published: February 2022

Aim. The aim of study is determine the potential of pharmacological activity in in silico modeling of a peptide with a confirmed anticoagulant effect, isolated from peloid. Materials and methods. The object of the study was previously obtained information on the amino acid sequence of the peptide isolated from the sapropel of Lake Big Taraskul. Its amino acid sequence was standardized according to international classifications (FASTA, SMILES) and processed using software (ADMETlab 2.0). The results of mathematical modeling in silico were correlated with our own experimental data of testing the compound in vitro and in vivo. Results. The data obtained by modeling the parameters of pharmacological activity in silico indicate that this amino acid sequence requires optimization of the chemical structure in terms of excretion directions, metabolic pathways in the liver, solubility and stability in aqueous solutions.
Method of preparation of tissue samples of ichthyofauna for toxicological studies of the Haff disease
Authors:   Tyumen State Medical University, Tyumen, Kalinin E. P. , Glazunova L. A. ,   State Agrarian University of the Northern Trans-Urals, Tyumen
Published: February 2022

Aim. The purpose of this study is to develop a methodology for preparing tissue samples from representatives of fish from reservoirs with suspected cases of Haff disease to optimize the conduct of confirmatory biological samples using laboratory animals. Materials and methods. The object of the study was representatives of fish species typical for the affected water bodies (silver carp, Carassius gibelio), as well as control samples of fish that are not a source of the etiological factor of the disease from water bodies of the Tyumen region. To optimize the preparation of material for biological samples, extracts of muscle homogenates and a complex of fish internal organs were obtained using various solvents. The design of the study was developed taking into account the possibility of extracting target chemical compounds from fish tissues that cause the symptoms of “Gaff disease”, as well as preventing the negative effects of the extractants themselves on experimental animals. When preparing the samples of extracts, the peculiarities of the diet and the time of development of the symptoms of the disease in experimental animals were taken into account. Results. Extracts suitable for biological testing were obtained from tissues of experimental and control fish samples using extractants that differ in their physicochemical characteristics and in the spectrum of chemical compounds soluble in them. A proprietary technique has been developed to ensure the most complete extraction of toxic compounds. Conclusion. The most convenient, both from a technological and chemical point of view, is an extract obtained from a homogenate of the muscle tissue of fish caught in affected reservoirs, obtained using a volatile weakly polar aprotic extractant. His further research is aimed at identifying chemical compounds that are the etiological factor that causes the symptoms of Haff disease.
Features of the daily dynamics of some biochemical parameters in Wistar rats of different sexes at the age of 6 months
Authors:   A. P. Avtsyn Research Institute of Human Morphology, Moscow, Kirillov Yu. A. ,   Tyumen State Medical University, Tyumen, Chernov I. A. ,   Tyumen State Medical University, Tyumen, Kozlova M. A. ,   A. P. Avtsyn Research Institute of Human Morphology, Moscow, Makartseva L. A. ,   A. P. Avtsyn Research Institute of Human Morphology, Moscow, Areshidze D. A. ,   A. P. Avtsyn Research Institute of Human Morphology, Moscow
Published: February 2022

Aim. To investigate the features of circadian rhythms (CR) of some biochemical constants in male and female Wistar rats at the age of 6 months. Materials and methods. The work was performed on 80 rats of the outbred Wistar drain at the age of 6 months, with a body weight of 350 g. The animals were kept under a fixed light regime (light / dark – 10 / 14 hours with the light turned on at 8.00 and off at 18.00). According to the sex, the rats were divided into 2 equal groups of 40 animals each. Blood sampling for biochemical studies was carried out 4 times a day with an interval of 6 hours. The levels of total protein, albumin, alanine aminotransferase (ALT), aspartate aminotransferase (AST), total bilirubin, glucose were determined in blood plasma using an analyzer. Results. The features of the daily dynamics and characteristics of the CR of the studied parameters in animals of different sexes are established. Conclusion. The results obtained indicate the need to take into account the features of the chronostructure of heterosexual organisms in research and practical activities.
Express method for determining the concentration of active substances in solutions of disinfectants
Authors:   Tyumen State Medical University, Tyumen, Kuznetsova O. M. , Kondratova S. E. ,   Tyumen State Medical University, Tyumen, Marchenko A. N. ,   Tyumen State Medical University, Tyumen
Published: February 2022

Disinfectants are in demand for use in any industrial sector: medical institutions (disinfection of premises, medical equipment), the food industry (for the destruction of fat and protein contamination), agriculture, social facilities (schools, kindergartens, swimming pools). In the prevention of infections associated with the provision of medical care (hereinafter ISMP) in a medical organization, the correct preparation of working solutions of disinfectants is of no small importance. The main problem of prevention of the spread of ISMP in medical organizations is timely monitoring of the preservation of the concentration of active substances in working solutions of disinfectants (hereinafter RRDS). First of all, this is due to the emergence of resistance of microorganisms when using disinfectant solutions with low or high concentrations of active substances. This problem is currently relevant due to the lack of a reliable express method for determining the concentration of active substances in working solutions of disinfectants in medical organizations against the background of the current epidemiological situation. This article highlights the results of the study of the innovative method of rapid determination of the concentration of active substances in RRDS in relation to viral infections.
Assessment of dietary zinc intake during pregnancy as a manageable risk factor for obstetric complications
Authors:   Perm State Medical University named after academician E.A. Wagner, Perm, Olina A. A. , Sadykova G. K. ,   Perm State Medical University named after academician E.A. Wagner, Perm, Pirozhnikova N. M. ,   Perm State Medical University named after academician E.A. Wagner, Perm
Published: February 2022

Objective of the study: to determine the frequency of the spread of zinc deficiency among pregnant women in Perm based on the analysis of the diet and laboratory data. Materials and methods. The actual nutrition and the level of zinc in the blood plasma were assessed in 417 women in the first trimester of pregnancy. Results and its discussion. On average, pregnant women consume 5.9 ± 2.1 mg / day, while the minimum level was 11.5 mg / day, the maximum – 1.55 mg / day. The recommended intake level of more than 12.5 mg / day was not recorded in any woman. Further, the level of zinc in the blood serum was studied in all patients, according to which the average level was 12.6 ± 0.6 μmol / L (the norm is 10.4-16.4 μmol / L). Zinc deficiency was identified in 262 women (62.8%). Conclusions. The study found that 80% of pregnant women with food do not receive the recommended daily intake of zinc. One in five patients had risk factors that exacerbated low zinc intake. The study showed that the optimal prophylactic dose of daily intake is 25 mg of zinc. For the selection of therapeutic dosages, a preliminary determination of the level of zinc in the blood serum is required.
Complex assessment of stress testing among women of reproductive age with normal and body mass excess in conditions of preconception care
Authors:   Tyumen State Medical University, Tyumen, Railian A. L. ,   Clinical Hospital “Mother and child”, Tyumen, Tomilova E. A. ,   Tyumen State Medical University, Tyumen, Kolpakov V. V. ,   Tyumen State Medical University, Tyumen, Galieva G. D. ,   Tyumen State Medical University, Tyumen, Nikolaenko T. A. ,   Tyumen State Medical University, Tyumen
Published: February 2022

Relevance. The progressive development of new orientation in preventive medicine and obstetric practice – preconception and prenatal cares, requires the active development and implementation of effective comprehensive programs to optimize physical activity, increase the functional body capacity and dynamic control of blood pressure among women of reproductive age. Materials and methods. At the background of practical implementation for the algorithm of sequential increase in the level of physical activity (apps on Android and Apple platforms) by 1 percentile for 7 days during 5-7 weeks, stress testing by treadmill test according to the modified protocol (R. Bruce) was carried out among 133 patients 20-35 years old with normal body mass (70 women – group One) and body mass excess (63 women – group Two). The assessment is for the tolerability level, for dynamics of body mass and blood pressure by comparison with the source (original) data. Results. In comparison with initial data after preconception care using the author’s algorithm at the background of reaching the sub-maximal CCR (cardiac construction rate) on the treadmill test, unidirectional positive effects of increasing exercise tolerance in both groups were established, but with higher indicators of metabolic equivalent, maximum oxygen consumption chronotropic reserve and shorter recovery time among women with normal body mass by comparison with women with BMI. Conclusions. The reached level of tolerance to physical activity and weight loss were combined with the increase in the effectiveness of pregnancy among the with BMI up to 52,3%. A comparative analysis of the results for complex assessment of load testing in both groups allow for a consistent centile increase in the daily number of locomotions up to 10-12 weeks and an approximation of body weight to the upper limit of the regulatory corridor (75-90 cents) among women with BMI, taking into account their personal consent and under the control of the results of stress testing and blood pressure indicators.
Experience of high-risk pregnancy of patient that has uterine myoma with uterine artery embolization in anamnesis
Authors:   Tyumen State Medical University, Tyumen, Vinokurova E. А. , Kolomiets E. V. ,   Tyumen State Medical University, Tyumen, Gorodnicheva I. Y. ,   Tyumen State Medical University, Tyumen
Published: February 2022

The increase in the frequency of uterine fibroids among women planning pregnancy is an actual problem. This pathology is the most common benign tumor of the female reproductive system, leading to complications during pregnancy and childbirth. One of the methods of surgical treatment of uterine fibroids in a significant number of patients is myomectomy. Patients with a history of uterine fibroids and myomectomy require close observation and a balanced choice of delivery tactics. This article describes a clinical case of high-grade management of a patient with uterine fibroids after embolization of the uterine nodes and subsequent surgical removal of the subserous node of uterine fibroids.
Clinical case of venous trophic ulcer treatment
Authors:   Tyumen State Medical University, Tyumen, Komarova L. N. ,   Clinical Hospital «RZD-Medicine» Tyumen», Tyumen, Nabieva K. U. ,   Tyumen State Medical University, Tyumen
Published: February 2022

Introduction. Varicose veins of the lower extremities with clinical form C2 and higher (if we take into account the modern international classification) is a slowly progressive disease. It needs therapy, besause if untreated, some complications can develop, such as: trophic disorders (lipodermatosclerosis, skin hyperpigmentation, trophic ulcers), bleeding from varicose veins with minimal trauma, thrombotic complications (varicothrombophlebitis, deep vein thrombosis, pulmonary embolism). Materials and methods. This article presents a description of a clinical case of an aged patient with a trophic ulcer of the lower third of the left leg against the background of varicose veins of the lower extremities in the saphenous vein system and the presence of concomitant moderate iron deficiency anemia, ischemic heart disease and hypertension. Considering these factors, endovenous radiofrequency ablation of the great saphenous vein and micro-foam echosclerotherapy of incompetent perforating veins of the leg were performed. Results and discussion. Our clinical observation of an aged patient with moderate iron deficiency anemia, ischemic heart disease and hypertension is an example of effective treatment of trophic ulcers against the background of varicose veins of the lower extremities in the saphenous vein system. Without waiting for the complete compensation of the anemia, the patient was operated on with a minimally invasive method, which contributed to the rapid healing of the trophic ulcer. As a result, after 2 weeks, the trophic ulcer decreased by 2 times, and 1 month after surgery and a 14-day course of infusion vascular therapy, the ulcer completely healed. Conclusion. Thus, in patients with an open trophic ulcer, the elimination of reflux (vertical and / or horizontal) at the initial stage of treatment creates ideal conditions for the fastest healing of the ulcer. The combination of minimally invasive methods of treatment (radiofrequency ablation and micro-foam sclerotherapy) and vascular therapy promotes rapid healing of trophic ulcers, shortens the recovery time of the body against the background of comorbid pathology, and provides a good cosmetic effect.
A rare case in clinical practice – sporadic hemiplegic migraine
Authors:   Tyumen State Medical University, Tyumen, Levitina E. V. , Rakhmanina O. A. ,   Tyumen State Medical University, Tyumen, Khramova E. B. ,   Tyumen State Medical University, Tyumen, Hayretdinova D. M. ,   Regional Clinical Hospital No. 2, Tyumen, Mokina A. V. ,   Regional Clinical Hospital No. 2, Tyumen
Published: February 2022

The article describes the peculiarities of a rare disease – hemiplegic migraine in 3 patients (two boy aged 7 and 15 years old and a girls of 12 years). The family history of migraine was not burdened. Attack symptoms were almost identical: hemiparesis, dysphasia, headache The electroencephalograms, magnetic resonance imaging in all patients not presented signs brain dysfunction. The considered description increases the awareness of doctors on the issue, which is very rare in the practice of pediatrician and neurologist.
Pengaruh Pengembangan SDM Terhadap Efektiviitas Kerja Gutu Tk-Negeri Se Kota Bandung
Authors: Suparjo Ojo
Published: February 2022

Masalah yang diselidiki dalam penelitian ini adalah pengaruh pengembangan sdm terhadap efektivitas kerja guru tk-negeri se kota bandung diduga masih rendah, diduga pengembangan sdm faktornya yaitu, perbedaan kemampuan, kesempatan berprestasi, peluang pengembangan diri, kerja sama, dan perlakuan yang sama terhadap aspek kualitas, tepat kuantitas dan tepat waktu belum optimal, sehingga menimbulkan komitmen organisasi yang kurang efisien. Metode penelitian yang digunakan adalah metode survei melalui penelitian deskriftif analisis serta penelitian verifikatif yakni menggambarkan dan menjeleaskan fenomena kinerja guru dengan meneliti hubungan antara variabel penelitian melalui pengujian hipotesis teknik analisis kuantitatif dengan fath analisis digunakan untuk mengetahui besarnya pengaruh variabel bebas terhadap variabel terikat. Hasil pengolahan dan analisis data di ketahui bahwa ada pengaruh yang signifikan antara pelaksanaan aspek-aspek pengembangan sumberdaya manusia terhadap efektivitas kerja guru tk-n se-kota Bandung, artinya pelaksanaan pengembangan sdm dapat memberikan kontribusi bagi kinerja guru tk-n se kota Bandung. Kesimpulan dinyatakan sebagai berikut: pertama, tingkat pengembangan SDM oleh TK-n se kota Bandung termasuk dalam kategori baik, kedua, secara parsial dan simultan dimensi-dimensi pengembangan SDM berpengaruh positif dan signifikan, pengembangan sdm yang mempunyai pengaruh terbesar terhadap efektifitas kerja guru tk-n se kota Bandung.
Pengaruh Kompetensi dan Kompensasi Terhadap Kinerja Pegawai dengan Motivasi Sebagai Variabel Intervening dalam Masa Pandemi
Authors: Susanto Andreas , Hadiyati Ernani , Adi Setia Kohar
Published: February 2022

Latar Belakang : Kinerja yang buruk dipengaruhi  kompetensi, kompensasi dan motivasi. dan juga di pengaruhi oleh kondisi kinerja di masa pandemi. Tujuan : Tujuan dari penelitian ini untuk mengetahui pengaruh motivasi terhadap hubungan kompetensi dan kompensasi dengan kinerja Pegawai Pemerintah Non Pegawai Negeri (PPNPN)  di Kantor Pertanahan Kabupaten Malang dalam masa pandemi. Metode : Jenis penelitian adalah kuantitatif dengan pendekatan Explanatory research, teknik pengambilan sampling adalah sampling jenuh dengan jumlah subjek 76 pegawai dan teknik analisa data menggunakan PLS. Hasil : Hasil penelitian menunjukkan Kompetensi pegawai berpengaruh signifikan terhadap kinerja pegawai Kantor Pertanahan Kabupaten Malang non PNS. Kompensasi yang diberikan Kantor Pertanahan Kabupaten Malang kepada pegawai berpengaruh signifikan terhadap kinerja pegawai Kantor Pertanahan Kabupaten Malang non PNS. Kesimpulan : Motivasi sebagai variabel intervening berpengaruh signifikan antara kompensasi dengan kinerja pegawai Kantor Pertanahan Kabupaten Malang non PNS dimasa pandemi.
Self Assessment dalam Hukum Pajak
Authors: Hapsari Putri Pramudya Arlini , Wibisono Arief , Mustafa Marni
Published: February 2022

Latar Belakang : Indonesia telah beberapa kali mengubah sistem pemungutan pajak mulai dari official assessment sistem, semiself assessment sistem, withholding sistem sampai dengan self assessment sistem. Tujuan : Penelitian ini bertujuan untuk mengetahui bagaimana penerapan sistem self assessment kepada wajib pajak. Metode : Metode penelitian ini menggunakan yuridis normatif yiatu penelaahan bahan kepustakaan yang meliputi bahan hukum primer, bahan hukum sekunder dan bahan hukum tertier, baik berupa dokumen maupun peraturan perundang-undangan. Hasil : Hasil penelitian menunjukkan sistem self assessment yang diterapkan belum dapat mengubah wajib pajak dalam melakukan kegiatan perpajakan secara mandiri dan jujur. Kesimpulan : Undang-undang memberikan kepercayaan kepada wajib pajak dengan sistem self assessment, akan tetapi tidak diiringi dengan kesadaran hukum yang baik oleh wajib pajak. Pengawasan dan penerapan sanksi yang tidak maksimal mengakibatkan tingginya pelanggaran yang dilakukan wajib pajak.
Pertumbuhan dan Hasil Tanaman Terong dengan Penambahan Pupuk Kandang dan Arang Sekam pada Media Tanam
Authors: Bachtiar Musthafa Muhammad
Published: February 2022

Latar Belakang : Terong adalah komoditas hortikultura yang banyak diminati masyarakat. Penambahan bahan organik dalam bentuk pupuk kandang dan arang sekam menjadi alternatif perbaikan kondisi tanah untuk mendukung pertumbuhan tanaman terong. Tujuan : Tujuan penelitian ini adalah untuk mengetahui perbedaan pertumbuhan dan hasil tanaman terong yang dipengaruhi oleh penambahan pupuk kandang dan arang sekam pada media tanamnya. Metode : Penelitian dilakukan di Desa Bantarwuni Kecamatan Kembaran Kabupaten Banyumas dengan ketinggian 110 m dpl. Penelitian menggunakan rancangan acak kelompok lengkap (RAKL) dengan faktor penambahan bahan organik berupa, kontrol (P0), pupuk kandang (P1), dan campuran pupuk kandang dan arang sekam (P2). Data yang diperoleh dianalis menggunakan uji F pada tingkat kesalahan 5 %, jika menunjukkan hasil signifikan dilanjutkan dengan uji DMRT. Variabel yang diamati adalah tinggi tanaman, jumlah daun, jumlah bunga, jumlah buah, dan bobot buah. Hasil : Hasil penelitian menunjukkan bahwa penambahan bahan organik tidak mempengaruhi pertumbuhan tanaman, tetapi mempengaruhi hasil yang diperoleh. Penambahan bahan organik berupa pupuk kandang dan arang sekam memberikan pengaruh terbaik dengan jumlah buah dan bobot buah secara berturut-turut 6,78 buah dan 1,36 kg per tanaman. Kesimpulan : Pemberian bahan organik berupa pupuk kandang dan arang sekam memberikan pengaruh terbaik terhadap jumlah buah dan bobot buah secara berturut-turut 6,78 buah dan 1,36 kg per tanaman.
Analisis Pengetahuan, Sikap dan Perilaku Berisiko Tertular Human Immunodeficiency Virus/Acquired Immuno Deficiency Syndrome (Hiv/Aids)
Authors: Wahyuni Sri , Putriastuti Widya , Samiadji Imam
Published: February 2022

Latar Belakang : Human immunodeficiency virus (HIV) menargetkan sistem kekebalan tubuh dan melemahkan sistem pertahanan manusia terhadap infeksi dan beberapa jenis kanker. Ketika virus merusak fungsi sel-sel kekebalan, individu yang terinfeksi secara bertahap menjadi imunodefisiensi. Tujuan : Meningkatkan kerentanan terhadap berbagai infeksi, kanker, dan penyakit lain yang dapat dilawan oleh orang dengan sistem kekebalan tubuh yang sehat. Metode : Metode penelitian yang digunakan yaitu desain penelitian deskriptif. Penentuan responden menggunakan purposive sampling dan diperoleh sebanyak 89 responden. Pengumpulan data berupa pengisian kuesioner dan studi dokumentasi. Dalam penelitian ini telah dilakukan uji etik oleh Lembaga Etik STIKes Budi Luhur Cimahi. Hasil : Hasil penelitian menunjukkan bahwa dalam rumah tahanan negara kelas I Bandung Hampir setengahnya memiliki tingkat pengetahuan yang cukup dengan jumlah responden sebanyak 36 responden, Sebagian besar memiliki sikap mendukung untuk mencegah penularan HIV/AIDS dengan jumlah responden 54 responden, Sebagian besar memiliki berisiko tertular HIV/AIDS dengan jumlah responden 48 responden. Kesimpulan : Analisis tingkat Pengetahuan terhadap warga binaan hampir setengahnya memiliki tingkat pengetahuan yang cukup dengan jumlah responden sebanyak 36 responden.
Gambaran Pengetahuan Ibu Balita Tentang Penanganan Diare Berdasarkan Karakteristik
Authors: Purba Meriati , Simbolon Nagoklan , Br Limbeng Meydiana
Published: February 2022

Latar Belakang : Diare merupakan salah satu penyebab utama angka kematian anak dan morobiditas di dunia yang menyebabkan tubuh kehilangan cairan dan mengalami dehidrasi. World Health Organization (WHO) memperkirakan 4 milyar kasus diare terjadi di dunia dan 2,2 juta diantaranya meninggal, dan sebagian besar anak anak dibawah umur 5 tahun. Tujuan : Tujuan dari penelitian ini untuk mengetahui pengetahuan ibu yang memiliki balita berdasarkan usia, agama, suku, pendidikan, pekerjaan dan penghasilan di Puskesmas Talun Kenas tahun 2021. Metode : Deskriptif dengan teknik consecutive sampling dimana pengumpulan datanya dilakukan menggunakan kuesioner. Hasil : Didapatkan bahwa dari 84 responden menunjukkan usia responden yang proporsi berada pada usia 26-35 tahun sebanyak 53 responden (63.1%), agama responden yang proporsi tertinggi islam sebanyak 38 responden (45.2%), suku responden  yang proporsi tertinggi karo sebanyak 65 responden (77.4%), pendidikan responden yang proporsi tertinggi SMA sebanyak 38 responden (45.2%), pekerjaan responden yang proporsi tertinggi tak bekerja/IRT sebanyak 46 responden (54.8%), dan penghasilan responden yang proporsi tertinggi rendah sebanyak 68 responden (81.0%). Sebagian besar ibu balita berpengetahuan cukup sebanyak 36 responden (42.9%). Kesimpulan : karakteristik demografi dapat mempengaruhi pengetahuan ibu balita dalam penanganan diare. Dilihat dari itu di wilayah Puskesmas Talun Kenas lebih banyak berpengetahuan cukup.
EKSISTENSI RUMAH MENTERI KERAJAAN INDRAGIRI SEBAGAI CAGAR BUDAYA
Authors: Dwi Yulia Srikandi
Published: February 2022

Existence is defined as existence. Where the existence is meant is the influence of our presence orabsence. This existence needs to be “given” by other people to us, because the response from people around us proves that our existence is acknowledged. The issue of the need for the value of existence is very important, because it is a proof of work or performance in an environment. Thisstudy discusses (1) the process of the Indragiri Kingdom Minister’s House as a CulturalConservation; (2) Efforts made by the Government in Managing the House of the Minister of the Kingdom of Indragiri as a Cultural Conservation; (3) The existence of the House of the Minister of the Kingdom of Indragiri as a Cultural Conservation. This type of research is qualitative research with a descriptive method, namely describing the answers through observation, interviews from informants and documentation and literature study. The collection of sources was obtained from the Regional Library of Indragiri Hulu Regency, Prof.Suwardi Library, Soeman H.S Pekanbaru Regional Library. As well as conducting interviews with families as heirs, historical observers of Indragiri Hulu Regency, related agencies and the people of Indragiri Hulu Regency, especially in the vicinity of the Cultural Heritage building. The results of the study showthat the House of the Minister of Maritime Affairs of the Indragiri Kingdom still visits not only local people but also national and even international tourists such as Malaysia, although experiencing ups and downs.
PELESTARIAN NILAI-NILAIBUDAYA PADA KESENIAN KUDA LUMPING DI KECAMATAN TAMBUSAI UTARA
Authors: RAHMAWATI ILHAM
Published: February 2022

This research is based on cultural issues. The aims of this research are (1) How to describe the preservation of cultural values ​​in Kuda Lumping art in North Tambusai District. This research is a qualitative research with ethnographic method. The sampling technique in this research is using a proposive sampling technique-nonprobalistic. Data analysis techniques used in this research are data reduction, data presentation, and conclusion drawing. The results of the study show that in Kuda Lumping art there are cultural values ​​that can be used as guidelines and references in people's lives including religious values, mutual cooperation values, responsibility values, unity values, ethical values, solidarity values ​​(togetherness), and aesthetic values. (beauty).
A INFLUÊNCIA DO EXERCÍCIO FÍSICO NA VIDA DOS IDOSOS
Authors: Passos Ricardo Pablo , Carvalho Anderson dos Santos , Pereira Adriano de Almeida , Carvalho Alexandre Freitas de , Martelli Anderson , Lima Bráulio Nascimento , Martins Gustavo Celestino , Oliveira Heleise Faria dos Reis de , Oliveira José Ricardo Lourenço de , Almeida Klebson da Silva , Silio Luis Felipe , Rodrigues Marcelo Francisco , Maneschy Mariela de Santana , Guedes Uebister Igor Dos Santos , Cavaco Paulo Manuel Barreiro , Abdalla Pedro Pugliesi , Vilela Junior Guanis de Barros
Published: February 2022

O processo de envelhecimento é algo natural do ser humano sendo comum a perca de agilidade, equilíbrio e redução da disposição física acarretando uma dependência de suas atividades. Assim, este trabalho apresentou como objetivo retratar a possibilidade de minimizar o processo de dependência e garantir uma autonomia e qualidade de vida maior aos idosos por meio da disponibilização e realização de exercícios físicos. Como metodologia, foi realizada uma revisão de literatura retratando a influência do exercício fisico na vida dos idosos. Como resultado foi observado que um envelhecimento sem a prática de exercício físico e outros hábitos saudáveis a população não consegue atingir seus objetivos e metas, acarretando uma dependência das atividades da vida diária, sendo que a atividade física é de extrema importância para esse público favorecendo qualidade de vida.
Perancangan Huruf dan Media Pembelajaran Aksara Sunda
Authors: Firdaus Muhammad Iqbal , Mariani Cecil , Adityayoga
Published: February 2022

Tahun 2013 aksara Sunda resmi menjadi konten kurikulum muatan lokal bahasa Sunda. Aksara Sunda diajarkan mulai dari tingkat Sekolah Dasar, Sekolah Menengah Pertama hingga Sekolah Menengah Atas. Setiap tingkatan pendidikan memberi materi pembelajaran aksara Sunda yang berbeda; dimulai dari pengenalan karakter aksara Sunda sampai dengan penggunaannya ke dalam media digital lewat media komputer. Pembelajaran aksara Sunda saat ini masih terbatas pada buku paket yang membuat murid cepat jenuh. Untuk itu, diperlukan pengembangan metode pembelajaran yang baru. Salah satu yang perlu dikembangkan adalah penggunaan huruf digital. Tulisan ini menjelaskan proses perancangan aksara Sunda dalam bentuk digital dengan tujuan pembelajaran aksara Sunda di sekolah lebih efektif dan menarik bagi siswa.
Urban Dynamic: Inspirasi Kemacetan Tanah Abang Jakarta
Authors: Maulana Iqbal , Pramudyawardani Retno Andri , Rosalin Yanni
Published: February 2022

Perkembangan varian trend fashion dapat dikembangkan melalui kombinasi antara situasi dan kondisi yang ada pada suatu daerah atau kota. Situasi Pusat Perbelanjaan Tanah Abang memberikan suatu ide tersendiri dalam membuat koleksi busana. Penelitian ini menjelaskan bagaimana implementasi dari suasana kemacetan yang terjadi di Pasar Tanah Abang, Jakarta Pusat, ke dalam suatu koleksi busana. Metode penelitian yang digunakan adalah kualitatif deskriptif. Hasil dari penelitian adalah koleksi busana berjudul Urban Dynamic yang bergaya sporty dramatic dengan tampilan urban contemporary.
KOMPETENSI PEDAGOGIK GURU DALAM PEMBELAJARAN MATEMATIKA KELAS V DI SDI TERPADU NURUL ANSHAR PADA MASA PANDEMI COVID-19 TAHUN AJARAN 2020/2021 KABUPATEN SITUBONDO
Authors: Rofek Aenor
Published: February 2022

Penelitian ini dilatarbelakangi oleh mayoritas guru di SD Islam Terpadu Nurul Anshar dalam kompetensi pedagogik guru dalam pembelajaran matematika, kondisi ini sangat unik karena peneliti ingin mengetahui kompetensi pedagogik guru selama masa pandemi covid-19. Metode penelitian yang digunakan dalam skripsi ini menggunakan metode penelitian deskriptif kualitatif yaitu suatu penelitian yang bertujuan untuk mendeskripsikan atau menggambarkan fenomena-fenomena yang ada, baik dari fenomena alamiah maupun fenomena rekayasa manusia. Hasil penelitian yang telah peneliti lakukan tentang kompetensi pedagogik guru dalam pembelajaran matematika kelas V di SD Islam Terpadu Nurul Anshar pada masa pandemi covid-19 yaitu pada Kemampuan Menyelenggarakan pembelajaran yang mendidik. hal tersebut menyebabkan hasil belajar siswa kurang maksimal. Ada beberapa faktor yang menyebabkan guru kurang optimal dalam pembelajaran matematika yaitu kurangnya waktu dalam proses pemberian materi dan penggunakan media pembelajaran yang menarik karena pada pandemi seperti ini sekolah menerapkan pembelajaran dengan 2 sesi yaitu sesi pertama siswa dibagi menjadi 2 kelompok. pada mata pelajaran matematika harus memiliki banyak waktu dan tambahan pembelajaran agar hasil belajar siswa sesuai dengan tujuan pembelajaran.
Peramalan Jumlah Permintaan Produksi Menggunakan Jaringan Saraf Tiruan Algoritma Backpropagation
Authors: Thoriq Muhammad
Published: February 2022

Artificial Neural Network (ANN) technique has developed rapidly in the field of estimation. ANN can predict based on data on events and related factors that existed in the past. ANN has advantages in parallel computing in classifying patterns. ANN is also capable of self-regulating the data to be processed without requiring an explicit function specification. The advantage of using ANN is the elimination of complex analytical and numerical iterative computations. The ANN method that is often used in prediction case studies is the Backpropagation Algorithm. This algorithm has the ability to solve problems in the real world by building trained methods that show good performance on large data scales and are able to overcome complex pattern recognition. This study aims to predict the demand for salt optimally using the ANN Method with the Backprogation Algorithm at PT. Kurnia Garam Prosperous Padang City. This forecasting is needed because of the high cost of production with the large number of requests that occur to be more effective. Proper forecasting will be able to optimize production so that it can reduce the required production costs. The data processed is salt production data from 2016 to 2018 at PT. Kurnia Garam Prosperous. The momentum results obtained are 3-9-1 for dividing the data into 2, namely 24 training data and 12 test data. The optimal prediction result is 0.98946, so this research is very helpful in forecasting optimal and efficient production costs.