bluuebunny/crossref_metadata_2025 huggingface dataset:
Water-energy-food nexus in urban sustainable development: an agent-based model
Authors: Li Guijun , Wang YongSheng , Huang Daohan , Yang Hongtao
Published: November 2017

Purpose

The purpose of this paper is to study how to effectively allocate water, energy and food (WEF) resources in urban development.

Design/methodology/approach

An agent-based model combined with NetLogo simulation model has been used in this paper.

Findings

This paper proposes a framework for agent analysis in urban WEF consumption.

Research limitations/implications

Further discussions using empirical data are of great importance.

Practical implications

Apply to form the development model of the city in the future.

Originality/value

A new method of WEF management has been used at the city level.
Intelligent interaction based on holographic personalized portal
Authors: Huang Yadong , Chai Yueting , Liu Yi , Gu Xiang
Published: November 2017

Purpose

The purpose of this paper is to study the architecture of holographic personalized portal, user modeling, commodity modeling and intelligent interaction.

Design/methodology/approach

In this paper, the authors propose crowd-science industrial ecological system based on holographic personalized portal and its interaction. The holographic personality portal is based on holographic enterprises, commodities and consumers, and the personalized portal consists of accurate ontology, reliable supply, intelligent demand and smart cyberspace.

Findings

The personalized portal can realize the information acquisition, characteristic analysis and holographic presentation. Then, the intelligent interaction, e.g. demand decomposition, personalized search, personalized presentation and demand prediction, will be implemented within the personalized portal.

Originality/value

The authors believe that their work on intelligent interaction based on holographic personalized portal, which has been first proposed in this paper, is innovation focusing on the interaction between intelligence and convenience.
Dovetailing talent management and diversity management: the exclusion-inclusion paradox
Authors: Daubner-Siva Dagmar , Vinkenburg Claartje J. , Jansen Paul G.W.
Published: November 2017

Purpose

The purpose of this paper is to adopt a paradox lens for dovetailing the human resource management sub-domains of talent management (TM) and diversity management (DM), in the attempt to create closer alignment between the two.

Design/methodology/approach

The authors review paradox theory, TM and DM literatures and formulate a paradox that becomes apparent when considering TM and DM simultaneously.

Findings

The authors coin this tension as the “exclusion-inclusion paradox,” highlighting that TM and DM reflect contradictory, yet interrelated principles: organizations promote exclusion through a TM architecture that focuses on the identification and development of a few selected employees, while simultaneously, organizations promote inclusion, in the attempt to minimize existing inequalities for traditionally marginalized groups.

Practical implications

Once uncovered, the exclusion-inclusion paradox enables organizational actors to make choices on whether to respond actively or defensively to the paradox. The authors argue for active responses in order to work through the paradox.

Originality/value

This is the first paper adopting a paradox lens in order to interweave the DM literature with TM literature in the attempt to explain how DM and TM constitute contradicting yet interrelated principles.
Effect of Sterilants on Amplification and Detection of Target DNA from Bacillus cereus Spores
Authors: Robertson James M. , Anders Douglas L. , Basalyga Francene , Millar Julie , Slack Donia Palomo , Bever Robert
Published: November 2017

To conceal criminal activity of a bioterrorist or agroterrorist, the site of pathogen generation is often treated with sterilants to kill the organisms and remove evidence. As dead organisms cannot be analyzed by culture, this study examined whether DNA from sterilant‐treated Bacillus cereus spores was viable for amplification. The spores were exposed to five common sterilants: bleach, Sterilox®, oxidizer foam (L‐Gel), a peroxyacid (Actril®), and formaldehyde vapor. The spores were inoculated on typical surfaces found in offices and laboratories to test for environmental effects. It was found that the surface influenced the efficiency of recovery of the organisms. The DNA isolated from the recovered spores was successfully detected using RT‐qPCR for all treatments except for formaldehyde, by amplifying the phosphatidylinositol phospholipase C and sphingomyelinase genes. The results demonstrated that evidence from sites treated with sterilants can still provide information on the uncultured organism, using DNA amplification.
Adherence to a multifactorial fall prevention program following paramedic care: Predictors and impact on falls and health service use. Results from an RCT a priori subgroup analysis
Authors: Mikolaizak A Stefanie , Lord Stephen R , Tiedemann Anne , Simpson Paul , Caplan Gideon , Bendall Jason C , Howard Kirsten , Close Jacqueline
Published: November 2017

Objective

To identify predictors and impact of adherence to a multifactorial fall‐prevention program on falls and health service utilisation.

Methods

Randomised controlled trial with a priori subgroup analysis within intervention group according to adherence. Participants were community dwelling, (≥65 years), not transported to hospital following fall‐related paramedic care. The Attitudes to Falls‐Related Interventions Scale (AFRIS) was completed at baseline, adherence levels were measured (three‐point scale) at six months, and falls and health service utilisation were recorded for 12 months. Multivariate logistic regression and area under the curve were calculated with 95% confidence interval (CI).

Results

Attitudes to Falls‐Related Interventions Scale scores (n = 85) were independent of baseline characteristics. At six months, 39 (46%) participants reported full adherence. Independent predictors of adherence were positive AFRIS (OR 4.10, 95% CI 1.48–11.39) and receiving 3+ recommendations (OR 3.36, 95% CI 1.26–9.00). Adherers experienced fewer falls (IRR 0.53, 95% CI 0.45–0.80) and fall‐related health service use (emergency department presentations IRR 0.37, 95% CI 0.17–0.82) compared to non‐adherers.

Conclusion

Older adults who adhere to recommendations benefit, regardless of fall‐risk profile.
Antenatal influenza and pertussis vaccine uptake among Aboriginal mothers in Western Australia
Authors: Lotter Kennia , Regan Annette K. , Thomas Tyra , Effler Paul V. , Mak Donna B.
Published: November 2017

Background

Antenatal influenza and pertussis vaccination prevent serious disease in mothers and infants. Aboriginal individuals are at increased risk of infection yet little is known about vaccine coverage among Aboriginal mothers.

Aims

To estimate the uptake of influenza and pertussis vaccination among pregnant Aboriginal women in Western Australia and identify barriers and enablers to vaccination.

Materials and methods

Four hundred Aboriginal women, aged ≥18 years, who gave birth to a live infant between April and October 2015, were randomly selected and invited to participate in telephone interviews. Of the 387 women who did not decline, 178 had a functioning phone number and 100 completed the survey. Analyses were weighted by maternal residence.

Results

During pregnancy the majority of Aboriginal mothers were recommended influenza (66%; unweighted, 65/96 = 68%) and pertussis (65%; unweighted, 62/94 = 66%) vaccines, with 62% (unweighted, 56/94 = 56%) and 63% (unweighted, 60/93 = 65%) receiving the vaccinations, respectively. Almost all vaccinated women (98%) reported wanting to protect their baby as the reason for immunisation. Rural mothers were more likely than metropolitan mothers to have been vaccinated against influenza (odds ratio (OR) 4.1, 95% CI 1.7–10.2) and pertussis (OR 3.1, 95% CI 1.2–7.6). Recommendation by a healthcare provider was strongly associated with vaccine uptake (influenza: OR 15.6, 95% CI 4.9–49.5; pertussis: OR 13.3, 95% CI 4.6–38.0).

Conclusion

Vaccination uptake among Western Australian Aboriginal mothers is comparable with rates reported for non‐Aboriginal populations worldwide. Provider recommendation is the single most important factor associated with vaccination uptake, underlining the importance of integrating vaccination into routine antenatal care.
Florence robotic intracorporeal neobladder (FloRIN): a new reconfiguration strategy developed following the IDEAL guidelines
Authors: Minervini Andrea , Vanacore Davide , Vittori Gianni , Milanesi Martina , Tuccio Agostino , Siena Giampaolo , Campi Riccardo , Mari Andrea , Gavazzi Andrea , Carini Marco
Published: November 2017

Objective

To describe our step‐by‐step technique for robotic intracorporeal neobladder configuration, including the stages of conception, development and exploration of this surgical innovation, according to the Idea, Development, Exploration, Assessment, Long‐term follow‐up (IDEAL) Collaboration guidelines.

Patients and Methods

The Florence robotic intracorporeal neobladder (FloRIN) was performed employing the following main surgical steps: isolation of 50 cm of ileum; bowel anastomosis; urethro‐ileal anastomosis creating an asymmetrical ‘U’‐shape (30 cm distally and 20 cm proximally to anastomosis), ileum detubularisation; posterior wall reconfiguration as an ‘L’; bladder neck reconstruction; anterior folding of the posterior plate to reach the 12 o'clock position; uretero‐enteral ‘orthotopic’ bilateral anastomosis. The conception and development of the FloRIN followed the IDEAL guidelines recommended stages: Phase 1 (simulation) involved the neobladder robotic configuration using silicone models. Phase 2a (development) aimed to reproduce the configuration in an open fashion in one patient, and then in the first three robotic procedures. Phase 2b (exploration) consisted of the technique standardisation in 15 consecutive robotic approaches. Phase 2a and 2b included urodynamics and imaging assessment of the patients treated.

Results

From February 2016 to September 2017 FloRIN was performed in 18 patients. Comparing the first three (Phase 2a) with the subsequent 15 patients (Phase 2b), the median (interquartile range [IQR]) reconstruction operating time was 260 (220–340) vs 160 (150–210) min, respectively. Postoperative surgical complications occurred in four of the 18 patients (22.1%), including one surgical Clavien–Dindo Grade III and three Grade I, postoperative medical Clavien–Dindo Grade II complications occurred in three (16.7%) patients. On urodynamic examination (available in nine [50%] patients) the median (IQR) reservoir cystometric capacity, compliance, and post‐void residual were 240 (220–267) mL, 18 (12.5–19.8) mL/cmH2O, and 0 (0–50) mL, respectively. Ultrasonography showed no Grade ≥2 vesico‐ureteric reflux.

Conclusion

We describe the FloRIN configuration, showing its technical feasibility with acceptable time efficiency. The first cases studied had good reservoir capacity, low pressure with no reflux, and complete voiding.
Fishing‐down within populations harms seed dispersal mutualism
Authors: Costa‐Pereira Raul , Correa Sandra Bibiana , Galetti Mauro
Published: November 2017

Large fish are often the most effective seed dispersers, but they are also the preferred target for fisheries. We recently started to comprehend the detrimental impacts of the extirpation of large frugivorous fish species on natural forest regeneration, but we lack a general understanding of how intraspecific size‐selective harvest affects fish–fruit mutualism. Our literature review demonstrated that large individuals within populations positively affect diverse aspects of seed dispersal, from consuming a higher diversity of seeds to enhancing germination. Furthermore, we filled a research gap by studying how individual size variations within two small frugivorous fish species (<16 cm) affect seed dispersal in flooded savannas. Even within small‐bodied species, large individuals swallow a higher number of intact seeds, but not necessarily a higher proportion. Overall, our results demonstrate the disproportional role of large‐bodied individuals as key seed dispersers in flooded habitats. Consequently, fishing‐down within both large‐ and small‐bodied species can negatively affect seed dispersal and natural regeneration in overfished wetlands.
Late Holocene slip rate and average recurrence interval of great earthquakes on the Shangzhi segment of the Yilan‐Yitong Fault Zone, northeastern China: Constraints from paleo‐earthquakes and historical written records
Authors: Yu Zhongyuan , Zhang Peizhen , Min Wei , Wei Qinghai , Liu Yugang
Published: November 2017

The Yilan‐Yitong Fault Zone (YYFZ) is considered to be the key branch of the Tancheng‐Lujiang Fault Zone (TLFZ) in northeastern China. Although the Mesozoic and early Cenozoic deformation of the YYFZ has been studied intensively over the past century, few estimates of slip rate and recurrence interval of large earthquakes in the late Quaternary, which are the two most important parameters for understanding the potential seismic hazard of this crucial structure, were obtained. Based on integrated interpretations of high resolution satellite images and detailed geologic and geomorphic mapping, linear landforms were identified, including fault scarps and troughs, along the Shangzhi segment of the YYFZ, which exceeds 25 km in length. Synthesized results of trench excavations and differential GPS measurements of terrace surfaces indicate that two events (E1, E2) occurred along the Shangzhi segment during the late Holocene, which resulted in 3.2 ±0.1 m of total vertical co‐seismic displacement with clear features of thrust motion.14C dating of samples suggests that event E1 occurred between 440 ±30 years BP and 180 ±30 years BP and that event E2 occurred between 4 090 ±30 years BP and 3 880 ±30 years BP, which indicates that the minimum vertical slip rate of the Shangzhi segment of the YYFZ has been approximately 0.8 ±0.03 mm/year during the late Holocene. Constraints from paleo events and the slip rate suggest that the average recurrence interval of major earthquakes on the YYFZ is 3 800 ±200 years. Historical documents in Korea show that event E1 possibly corresponds to the earthquake that occurred in AD 1810 (the Qing Dynasty in Chinese history) in the Ningguta area, which had surface‐wave magnitude (Ms) of 6.8–7.5. Studies of kinematics show that the right‐lateral strike‐slip with a reverse component has been dominant along the YYFZ during the late Holocene.
Improving quality of fresh‐cut mango using polysaccharide‐based edible coatings
Authors: Salinas‐Roca Blanca , Guerreiro Ariadna , Welti‐Chanes Jorge , Antunes Maria D. C. , Martín‐Belloso Olga
Published: November 2017

This study was aimed at evaluating the effect of coatings with alginate (AL), pectin (PE), carboxymethyl cellulose (CMC) or chitosan (CH) on microbial stability, physicochemical attributes, total phenolics and carotenoids content, antioxidant capacity and sensory properties of fresh‐cut mango during 14 days at 4 ± 1 °C. Coated fresh‐cut mango kept microbial counts below 6 logs CFU g−1, being CH‐coated fresh‐cut mango those that exhibited the lowest microbial counts (1 log CFU g−1) along entire storage. AL, PE and CMC coatings maintained yellow colour of fresh‐cut mango throughout storage. AL and CH coatings, which have different monomers in their chain, improved the content of antioxidant compounds in fresh‐cut mango as related to uncoated. AL‐coated fresh‐cut mangoes were the toughest, among those coated, during 14 days. The highest consumer acceptance was achieved in AL (90.2%) coated fresh‐cut mango. CH would be the most suitable coating to extend the quality of fresh‐cut mango throughout storage.
Dissecting human ILC heterogeneity: more than just three subsets
Authors: Simoni Yannick , Newell Evan W.
Published: November 2017

Innate lymphoid cells (ILCs) have been divided into three distinct groups based on functional capacities, cytokine profiles and transcription factor expression. Studies performed mainly in mice have demonstrated the importance of ILCs in chronic inflammation, infection, allergy and cancer. In this review, we discuss the heterogeneity of human ILC and focus primarily on the taxonomy of human ILC cell subsets and their phenotypical and functional diversity. We summarize recent findings concerning the diversity of ILCs between and within the major subsets [natural killer (NK), ILC1, intra‐epithelial ILC1 (ieILC1), ILC2, ILC3, lymphoid tissues inducer (LTi) and ILC progenitor (ILCP)], as well as the abundance of each in human tissues. We also discuss the similarities observed between groups of cells in term of receptors expressed and cytokines produced, and how these relate to the pleiotropic properties of each subset.
Aluminum‐enhanced alkali diffusion from float glass to PVD‐sputtered silica thin films
Authors: Fonné Jean‐Thomas , Burov Ekaterina , Gouillart Emmanuelle , Grachev Sergey , Montigaud Hervé , Vandembroucq Damien
Published: November 2017

Interdiffusion processes between aluminum enriched PVD‐sputtered silica thin films and industrial float soda‐lime silicate glass substrates are quantitatively studied using SIMS analysis. Heat treatments are performed at temperatures close or above the glass transition temperature of the float glass. Aluminum doping of the film is shown to strongly increase the migration of alkali from the glass substrate to the silica thin film. In particular the final alkali content in the film exhibits a linear scaling with the aluminum concentration. An interdiffusion process is evidenced between bulk alkali ions and protons originating from a significant water content in the as‐deposited silica film. Experimental measurements of sodium concentration are shown to be consistent with a simple thermodynamic model based on the equilibration of the activity of sodium between the film and the glass substrate.
Protocol for a new concept of no‐prep ultrathin ceramic veneers
Authors: D'Arcangelo Camillo , Vadini Mirco , D'Amario Maurizio , Chiavaroli Zaccheo , De Angelis Francesco
Published: November 2017

Objectives

No‐prep veneers, although ideally considered the best option because of tooth structure maximum preservation, have been frequently criticized for some potential limitations including esthetic outcomes and periodontal complications.

Clinical considerations

A new protocol to optimize no‐prep veneers restorations is presented. A key point of the proposed technique is to identify optimal margins’ positions: margin is positioned in the point of maximum convexity of teeth, avoiding the over contouring of traditional no‐prep veneers.

Conclusion

The procedure can be appreciated for the marginal accuracy and the resulting aesthetic stability. The case reports show that properly managed no‐prep veneers can have biologically healthy and aesthetically pleasant tooth‐restoration transitions and emergence profiles.

Clinical Significance

High‐quality no‐prep veneers can be more challenging to realize than conventional veneers and the success seems to depend on a combination of good case selection, margins’ position, sound adhesive principles, clinical, and laboratory experience.
Reproductive biology of female striped marlin Kajikia audax in the western Pacific Ocean
Authors: Chang H.‐Y. , Sun C.‐L. , Yeh S.‐Z. , Chang Y.‐J. , Su N.‐J. , DiNardo G.
Published: November 2017

Length and mass data for 1260 (536 females, 683 males, 41 sex unknown) striped marlin Kajikia audax were collected at the fish markets of Tungkang, Singkang and Nanfangao from July 2004 to September 2010. Of these samples, 534 gonads (236 females and 298 males) ranging from 95 to 206 cm in eye‐to‐fork length (LEF) and 8 to 88 kg in round mass (MR), were collected. Chi‐square tests indicated sex ratios were homogeneous among months in 2004 and 2006–2008, but not in 2005, 2009 and 2010; and there were significant differences in sex ratio by size. The overall sex ratio (RS) differed significantly from the expected 0·5. Kajikia audax are sexually dimorphic and the proportions of females increased with size between 140 and 210 cm LEF. Reproductive activity was assessed using a gonado‐somatic index (IG), external appearance of the gonads and histological examination and results indicated that the spawning season occurred from April to August with a peak in June to July. Based on histological observations and the distribution of oocyte diameters, K. audax are multiple spawners and their oocytes develop asynchronously. The estimated length‐at‐50% maturity (LEF50) was c. 181 cm (c. 4·8 years of age) for females. The proportion of reproductively active females in the spawning season with ovaries containing postovulatory follicles (0·27) indicated that they spawned every 3·7 days on average. The hydrated oocyte method estimated mean ± S.D. batch fecundity (FB) to be 4·4 ± 2·02 million eggs; average relative fecundity was 53·6 ± 13·9 oocytes g−1 MR; and the average annual fecundity was 181·3 ± 48·3 million eggs. The parameters estimated in this study are key information for stock assessments of K. audax in the north‐western and central Pacific and will contribute to the conservation, management and sustainable yield of this species.
Feasibility of intraperitoneal placental‐derived mesenchymal stem cell injection in stomachs of diabetic mice
Authors: Park Jong Min , Lee Sang Hwan , Kim Kwang Il , Kim Won Hee , Cho Joo Young , Hahm Ki Baik , Hong Sung Pyo
Published: November 2017

Background and Aim

Diabetic gastropathy is associated with loss of interstitial cells of Cajal and autonomic neuropathy. Effective management for diabetic gastropathy is still unavailable. This study was aimed to confirm the pathogenetic changes in diabetic gastropathy and to examine the effect of treatment with placental‐derived mesenchymal stem cells (PDMSCs) in stomachs of animal models.

Methods

Fourteen non‐obese diabetic/ShiLtJ mice of 8 weeks were bled until week 30. Diabetes mellitus developed in 10 out of 14 mice, which all survived with insulin. The mice were grouped into three groups: nondiabetic group (n = 4), diabetic sham group (n = 5), and diabetic PDMSC group (n = 5) all of which were treated with intraperitoneal PDMSCs injection at week 30. All mice were killed at week 34, and the stomachs were examined by immunohistochemical stain with c‐kit and neuronal nitric oxide synthase antibodies.

Results

The number of c‐kit positive cells in stomach decreased significantly in the diabetic sham group compared with that in the nondiabetic group (21.2 ± 6.7 vs 88.0 ± 29.3, P = 0.006) but increased with PDMSC treatment (21.2 ± 6.7 vs 64.0 ± 15.1, P = 0.02). The positive rate of neuronal nitric oxide synthase in neural plexus was also significantly lower in the diabetic sham group than in the nondiabetic group (22.3% ± 18.5% vs 48.0% ± 22.7%, P = 0.003) but increased with PDMSC treatment (22.3% ± 18.5% vs 43.3% ± 20.5%, P = 0.03).

Conclusions

Interstitial cells of Cajal and neural plexus decreased in stomachs of mice with diabetes mellitus but were significantly repaired with intraperitoneal injection of PDMSC.
Giant intracranial arteriovenous malformation as the focus of epileptic seizures
Authors: Takayama Mio , Hara Kenji , Matsusue Aya , Waters Brian , Ikematsu Natsuki , Kashiwagi Masayuki , Kubo Shin‐ichi
Published: November 2017

A man in his late thirties was found in a supine position in the hallway of his house. He had been diagnosed with epilepsy at approximately 20 years old. Since stopping treatment, epileptic events occurred more frequently and his condition deteriorated in the past 2 years. Autopsy revealed that head injuries were found on the left side of his head. A fracture from the left parietal bone to the anterior cranial fossa was also detected. A subdural hemorrhage (hematoma) spanned a wide range. A subarachnoid hemorrhage was also identified in the left parietal region. His brain weighed 1603 g, was edematous, and showed right uncal herniation. In the right cerebral hemisphere, a thick, enlarged blood vessel ran from the sagittal sinus. An egg‐sized tumorous lesion of blood vessels was found on the bottom of the frontal lobe. This vascular lesion had formed between the sagittal sinus and right anterior cerebral artery. Pathologically, veins and arteries were found together, and, thus, this case was diagnosed as an arteriovenous malformation (AVM). No other pathological and toxicological findings were observed. Subdural hematoma, the cause of death, occurred from the fall to the floor. An epileptic seizure may have been the cause of the fall. AVM on his brain was considered to be the focal lesion of epileptic seizures.
Seronegative granulomatosis with polyangiitis presenting with multiple cranial nerve palsies
Authors: Lee Eunhye , Park Jynkyun , Choi Seung Hong , Park Sung‐Hye
Published: November 2017

Granulomatosis with polyangiitis (GPA), previously known as Wegener’s granulomatosis (WG), is a rare systemic disease characterized by necrotizing granulomas and vasculitis that usually presents in the respiratory tract and renal system. Here, we report a case of anti‐neutrophil cytoplasmic antibody (ANCA)‐negative GPA with diagnostic difficulties. Neurologic involvement in GPA is not uncommon, with up to 50% of patients manifesting with neurologic defects; however, it is usually a late event. This patient was a 50‐year‐old man whose first manifestation was multiple neurologic defects without respiratory or renal symptoms. Since multiple neurologic deficits were the first manifestation and there were no pulmonary or renal symptoms, our patient was treated for 1 year for suspected infectious or inflammatory diseases such as non‐tuberculous mycobacterial infection or immunoglobulin G4 (IgG4)‐related disease with brain involvement; however, his symptoms would wax and wane. Reanalysis of the laboratory findings including biopsies, finally revealed this case to be compatible with GPA. Here, we report a case of GPA, focusing on the diagnostic pitfalls.
Long‐term clinical and echocardiographic outcomes of Mitraclip therapy in patients nonresponders to cardiac resynchronization
Authors: Giaimo Valerio L. , Zappulla Paolo , Cirasa Arianna , Tempio Donatella , Sanfilippo Maria , Rapisarda Giulia , Trovato Danilo , Grazia Angelo Di , Liotta Claudio , Grasso Carmelo , Capodanno Davide , Tamburino Corrado , Calvi Valeria
Published: November 2017

Objectives

This study deals with clinical and echocardiographic outcomes in cardiac resynchronization therapy (CRT) nonresponders patients undergoing Mitraclip procedure.

Background

Functional mitral regurgitation (FMR) occurs in approximately one‐third of heart failure (HF) patients. Resynchronization therapy may correct FMR in patients with HF; however, significant FMR persists in 20–25% of CRT patients.

Methods

All patients included were previously treated with CRT for at least 6 months and remained classified as New York Heart Association (NYHA) functional class III or IV despite optimal medical therapy; the echocardiographic assessment showed lack of decrease of the left ventricular end‐systolic volume (LVESV) of at least 10% and residual moderate‐to‐severe or severe FMR. Clinical and echocardiographic follow‐up was scheduled at 1, 3, 6, and 12 months after Mitraclip implantation, and every 6 months thereafter.

Results

Thirty patients fulfilled inclusion criteria. Before Mitraclip implantation NYHA class was III in 83% and IV in 17% of patients; after CRT no patient experienced an improvement in FMR. There was a significant improvement in NYHA class from baseline to 6 months, which remained sustained at 12 and 24 months. The degree of FMR significantly improved from baseline to 6 months and from 6 to 12 months. There was left ventricle remodeling with significant reduction of LVESV and an increase of left ventricle ejection fraction at 6 and 12 months, while the opposite trend was noted between 12 and 24 months

Conclusion

Treatment of moderate to severe FMR in CRT nonresponder is feasible, safe, and reasonably effective in reducing cardiac symptoms.
Leukocyte adhesion defect‐I: rare primary immune deficiency
Authors: Tewari Nitesh , Mathur Vijay Prakash , Yadav Vikender Singh , Chaudhari Prabhat
Published: November 2017

Leukocyte adhesion defect I is a rare disorder (1:1,000,000) caused by diminished expression of CD‐18 β2 integrins on leukocytes leading to abnormal adhesion, migration, and chemotaxis. Clinical manifestations include delayed separation of umbilical cord, omphalitis, recurrent severe infections, impaired wound healing, persistent oral ulcers, and severe periodontitis in primary and permanent dentition.

A 5‐year‐old girl, second‐born child to parents with consanguinity, presented with pain and mobility of lower teeth. There was history of recurrent infections and multiple hospital admissions with CD18 level‐3% and frame shift mutation in ITGB2, on 21q22.3. There were scars on hands and feet. Oral examination revealed multiple missing teeth and periodontitis in primary dentition. Oral prophylaxis and palliative treatments were performed with periodic follow‐ups.

Interdisciplinary care is ubiquitous for patients with immune deficiencies. Early consultation with pediatric dentists and exploration of medical history is essential for diagnosis and treatment of rare diseases.
Actitudes sexistas y asunción de responsabilidad en agresores condenados por violencia de género.
Authors: Guerrero-Molina Mónica , Moreno-Manso Juan Manuel , Guerrero-Barona Eloísa , Cruz-Márquez Beatriz
Published: November 2017

La presente investigación analiza la atribución de responsabilidad y las actitudes sexistas de 129 agresores condenados por violencia de género. Se aplicó la Escala de Atribución de Responsabilidad y Minimización y el Inventario de Sexismo Ambivalente (ASI). Los resultados señalan que un porcentaje elevado de agresores tiende a asumir la responsabilidad por la violencia ejercida y no justifica la agresión. Asimismo, se ha constatado que los condenados no presentan un número elevado de actitudes sexistas. No obstante, las actitudes sexistas permiten predecir la minimización del daño por parte de los agresores. Las conclusiones redundan en la importancia de intervención con esta población, dada la eficacia de los programas en la asunción de responsabilidad y en la disminución de actitudes sexistas.
Calidad de vida, emociones negativas, autoeficacia y calidad del sueño en pacientes con dolor crónico: efectos de un programa de intervención psicológica
Authors: Van-der Hofstadt Román Carlos Javier , Leal Costa César , Alonso Gascón Miguel Raul , Rodríguez Marín Jesús
Published: November 2017

El dolor crónico es un problema de salud que afecta a entre el 10 y el 30% de la población. El objetivo del presente estudio consiste en evaluar la eficacia de un programa de intervención grupal en dolor crónico. Se realizó un estudio cuasi experimental. La muestra estuvo compuesta por 105 participantes de la Unidad de Dolor del Hospital General Universitario de Alicante. Se administró una batería de cuestionarios pre y post a la aplicación del programa. En el estudio se midió el nivel de dolor, la calidad de vida, ansiedad, depresión, atributos del sueño y autoeficacia. Se obtuvieron mejoras significativas en los niveles de ansiedad, depresión calidad de vida física, autoeficacia en todas sus dimensiones (control de síntomas, funcionamiento físico y control del dolor) y aspectos de los atributos del sueño, como cantidad y alteraciones del sueño. El programa protocolizado y realizado por profesionales entrenados es efectivo para disminuir la percepción del dolor, aumentar la calidad de vida en su componente físico, mejorar la autoeficacia y los atributos del sueño en pacientes con dolor crónico.
Envejecimiento en parálisis cerebral, un reto en investigación e innovación: revisión sistemática
Authors: González-Alonso María Yolanda , García-Moltó Amelia , Ovejero Bruna María Mercedes
Published: November 2017

Apenas existen iniciativas de investigación en el ámbito del envejecimiento activo y saludable de las personas con parálisis cerebral. Encontrar soluciones a este reto social requiere una red de excelencia en investigación que contribuya a vivir mejor a toda la sociedad. Se recopiló información sobre parálisis cerebral y envejecimiento concretamente sobre necesidades percibidas, calidad de vida y repercusión del envejecimiento en las personas con parálisis cerebral. Se revisaron los conceptos que constituyen el marco teórico para investigar. A continuación se analizó la literatura encontrada sobre el proceso de envejecimiento. Por último se recogieron atendiendo a los principios de igualdad de oportunidades, no discriminación y accesibilidad universal, líneas de actuación a tener en cuenta por los investigadores en el desarrollo de actividades innovadoras. Invertir en investigación e innovación es esencial para el futuro, es la manera de impulsar productos y servicios y así crear una sociedad mejor para todos los ciudadanos.
Investigaciones y comprensiones del conflicto armado en Colombia. Salud mental y familia
Authors: Venegas Luque Rocio , Gutierrez Velasco Alexandra , Caicedo Cardeñosa Maria Fernanda
Published: November 2017

El conflicto armado en Colombia se ha configurado en los últimos 50 años en una de las problemáticas sociales de mayor complejidad, que reta novedosas respuestas disciplinares. Este artículo revisa las investigaciones y comprensiones desarrolladas alrededor del tema en los últimos 15 años, focalizando el abordaje en salud mental y familia como categorías relevantes a la luz de los actos administrativos jurídicos y sociales , de reparación material y simbólica, a las víctimas en el contexto histórico de transición del conflicto Se analizaron 62 documentos entre artículos investigativos de carácter cuantitativo y cualitativo, revisiones teóricas y textos de experiencias profesionales, y proyectos; ubicados en bases de datos y medios electrónicos de índole académicos que abordan la temática. Se aprecia una creciente tendencia a reconocer la interrelación de diferentes dimensiones bío-psico-sociales inmersas en las evaluaciones e intervenciones; y sin embargo, se requiere generar indicadores útiles para los procesos de reparación integral, (para lo cual se encuentran significativas las categorías propuestas) y fortalecer los abordajes interdisciplinares.
A Detailed Study of the Effects of Biodiesel Addition and Exhaust Gas Recirculation on Diesel Engine PCCI Combustion, Performance and Emission Characteristics by KIVA–CHEMKIN Coupling
Authors: Zehni Alborz , Saray Rahim Khoshbakhti , Neshat Elahe
Published: November 2017

In this study, a numerical study is performed by KIVA–CHEMKIN code to investigate the effects of biodiesel addition and exhaust gas recirculation (EGR) on diesel engine premixed charge compression ignition (PCCI) combustion, performance, and emission characteristics. The studies are performed for neat diesel fuel and mixture of 10–40% biodiesel addition at 67%, 50%, and 40% EGR. For this purpose, a multichemistry surrogate mechanism using methyl decanoate (MD) and methyl-9-decenoate (MD9D) is used. The main innovation of this work is analyzing the chemical, thermodynamic, and dilution effects of biodiesel addition as well as different EGR ratios on PCCI combustion behavior. The results show that the main effect of EGR on PCCI combustion of biodiesel blend is related to the high temperature heat release (HTHR), and its effect on low temperature heat release (LTHR) is low. With increasing biodiesel addition, the role of the chemical effect is increased compared to the thermodynamic and dilution effects. Rate of production analysis (ROPA) indicate that for the different biodiesel ratios, the effect of reaction nC7H16 + HO2 = C7H15-2 + H2O2 is more effective on the start of combustion (SOC) compared to the other reactions. For a defined biodiesel addition, with decreasing EGR, total (unburned) hydrocarbon (THC) and CO are decreased, while NOx and indicated specific fuel consumption (ISFC) are increased.
Potential and Limitations of Dual Fuel Operation of High Speed Large Engines
Authors: Redtenbacher Christoph , Kiesling Constantin , Malin Maximilian , Wimmer Andreas , Pastor José V. , Pinotti Mattia
Published: November 2017

The aim of this paper is to identify and investigate the potential and limitations of diesel–gas combustion concepts for high speed large engines operated in gas mode with very small amounts of pilot fuel (<5% diesel fraction). Experimental tests were carried out on a flexible single cylinder research engine (displacement 6.24 dm3) equipped with a common rail system. Various engine configurations and operating parameters were varied and the effects on the combustion process were analyzed. The results presented in this paper include a comparison of the performance of the investigated dual fuel concept to those of a state-of-the-art monofuel gas engine and a state-of-the-art monofuel diesel engine. Evaluation reveals that certain limiting factors exist that prevent the dual fuel engine from performing as well as the superior gas engine. At the same NOx level of 1.3 g/kWh, the efficiency of the dual fuel engine is ≈3.5% pts. lower than that of the gas engine. This is caused by the weaker ignition performance of the injected pilot fuel compared to that of the gas scavenged prechamber of the gas engine. On the other hand, the dual fuel concept has the potential to compete with the diesel engine. The dual fuel engine can be operated at the efficiency level of the diesel engine yet with significantly lower NOx emissions (3.5 g/kWh and 6.3 g/kWh, respectively). Since the injection of pilot fuel is of major importance for flame initialization, and thus for the main combustion event of the dual fuel engine, optical investigations in a spray box, measurements of injection rates, and three-dimensional (3D) computational fluid dynamics (CFD) simulation were conducted to obtain even more detailed insight into these processes. A study on the influence of the diesel fraction shows that diminishing the diesel fraction from 3% to lower values has a significant impact on engine performance because of the effects of such a reduction on injection, ignition delay, and initial flame formation. The presented results illustrate which operating strategy is beneficial for engine performance in terms of low NOx emissions and high efficiency. Moreover, potential measures can be derived which allow for further optimization of the diesel–gas combustion process.
Budgets of Disturbances Energy for Nozzle Flows at Subsonic and Choked Regimes
Authors: Huet Maxime
Published: November 2017

The noise generated by the passage of acoustic and entropy perturbations through subsonic and choked nozzle flows is investigated numerically using an energetic approach. Low-order models are used to reproduce the experimental results of the hot acoustic test rig (HAT) of Deutsches Zentrum für Luft- und Raumfahrt (DLR), and energy budgets are performed to characterize the reflection, transmission, and dissipation of the fluctuations. Because acoustic and entropy perturbations are present in the flow in the general case, classical acoustic energy budgets cannot be used and the disturbances energy budgets proposed by Myers (1991, “Transport of Energy by Disturbances in Arbitrary Steady Flows,” J. Fluid Mech., 226, pp. 383–400.) are used instead. Numerical results are in very good agreement with the experiments in terms of acoustic transmission and reflection coefficients. The normal shock present in the diffuser for choked regimes is shown to attenuate the scattered acoustic fluctuations, either by pure dissipation effect or by converting a part of the acoustic energy into entropy fluctuations.
Formation of supramolecular protein structures on gold surfaces
Authors: Domigan Laura J. , Ashmead Helen , Dimartino Simone , Malmstrom Jenny , Grant Pearce F. , Blunt Matthew , Williams David E. , Gerrard Juliet A.
Published: November 2017

Recent research has highlighted the exciting possibilities enabled by the use of protein structures as nanocomponents to form functional nanodevices. To this end, control over protein–protein and protein–surface interactions is essential. In this study, the authors probe the interaction of human peroxiredoxin 3 with gold surfaces, a protein that has been previously identified as having potential use in nanotechnology. Analytical ultracentrifugation and transmission electron microscopy revealed the pH mediated assembly of protein toroids into tubular structures across a small pH range. Quartz crystal microbalance with dissipation measurements showed differences in absorbed protein mass when pH is switched from pH 8.0 to 7.2, in line with the formation of supramolecular structures observed in solution studies. Scanning tunneling microscopy under ambient conditions showed that these protein tubes form on surfaces in a concentration dependent manner, with a tendency for protein adsorption and supramolecular assembly at the edges of Au(111) terraces. Finally, self-assembled monolayer modification of Au surfaces was explored as a means to control the adsorption and orientation of pH triggered protein structures.
Coevaporation and structuring of titanium–aluminum alloy thin films
Authors: Lattner Eric , Seifert Marietta , Gemming Thomas , Heicke Steffen , Menzel Siegfried B.
Published: November 2017

Intermetallic phases of binary material systems, such as TiAl, Ti3Al, RuAl, and Ni3Al have special physical properties such as a high oxidation resistance and low creep at high temperatures and a mechanical stability over wide temperature ranges. Due to new fields of application, such phases became increasingly important in the last two decades. In general, alloys can be sputtered very easily and reproducible. In surface acoustic wave (SAW) technology and microelectronics, the lift-off structuring technique is a fundamental process in the production of structured thin (<500 nm) metallic electrodes especially for low-cost fabrication of interdigital transducers (IDT). However, the structuring by standard lift-off technology only results in high quality IDTs for evaporated and not for sputtered layers. In order to investigate the intermetallic phases of the binary Ti-Al material system for IDT fabrication for SAW technology, a modified evaporator system for the simultaneous deposition of the low (Al) and the high (Ti) melting materials is presented.
Effect of Mo on the thermal stability, oxidation resistance, and tribo-mechanical properties of arc evaporated Ti-Al-N coatings
Authors: Glatz Stefan A. , Moraes Vincent , Koller Christian M. , Riedl Helmut , Bolvardi Hamid , Kolozsvári Szilárd , Mayrhofer Paul H.
Published: November 2017

The general tendency in industrial machining and forming operations toward further reduced operation time and increased efficiency requires continuous improvements of protective coatings regarding their tribo-mechanical properties. Alloying arc evaporated Ti1-xAlxN with small amounts of molybdenum (Mo) has shown very promising results to further improve the tribological properties of the industrially widely used Ti-Al-N. Therefore, the authors study in detail the effect of Mo on the thermo-mechanical properties of Ti1-xAlxN coatings, as well as their wear behavior at elevated temperatures. First principle density functional theory (DFT) calculations are conducted for face-centered cubic c-Al1-yMoyN, c-Ti1-yMoyN, and c-Ti1-x-yAlxMoyN showing increasing energy of formation with increasing Mo incorporation for all structures investigated. However, the thereby (DFT) obtained/calculated lattice parameters for comparable compositions perfectly matches with those of the single-phase face-centered cubic structured c-Ti0.55Al0.42Mo0.03N, c-Ti0.53Al0.41Mo0.06N, and c-Ti0.50Al0.38Mo0.12N coatings studied. These coatings have an as deposited hardness of about 28 GPa, which can be maintained upon vacuum annealing up to Ta = 800 °C. At higher temperatures, their hardness decreases as the formation of the weaker w-AlN and Mo3Al phases occurs. In contrast to that, the abrasive wear of Mo-containing c-Ti1-x-yAlxMoyN during dry-sliding high temperature ball-on-disk tests (against 6 mm alumina balls at 700 °C) is significantly reduced to 1–2.0 × 10−6 mm3/N m, as compared to the Mo-free Ti0.56Al0.44N counterpart. This is the result of the presence of solid lubricant MoO3 phases in the wear tracks of the arc evaporated c-Ti1-x-yAlxMoyN coatings investigated—confirmed by a combined energy dispersive spectroscopy and x-ray photoelectron spectroscopy analysis. Based on their findings, the authors can conclude that the addition of up to 12 at.% Mo (of the metal fraction) to Ti0.56Al0.44N significantly improves their high temperature wear resistance by simultaneously keeping the outstanding coating characteristics of pure Ti1-xAlxN.
Detection of keyboard vibrations and effects on perceived piano quality
Authors: Fontana Federico , Papetti Stefano , Järveläinen Hanna , Avanzini Federico
Published: November 2017

Two experiments were conducted on an upright and a grand piano, both either producing string vibrations or conversely being silent after the initial keypress, while pianists were listening to the feedback from a synthesizer through insulating headphones. In a quality experiment, participants unaware of the silent mode were asked to play freely and then rate the instrument according to a set of attributes and general preference. Participants preferred the vibrating over the silent setup, and preference ratings were associated to auditory attributes of richness and naturalness in the low and middle ranges. Another experiment on the same setup measured the detection of vibrations at the keyboard, while pianists played notes and chords of varying dynamics and duration. Sensitivity to string vibrations was highest in the lowest register and gradually decreased up to note D5. After the percussive transient, the tactile stimuli exhibited spectral peaks of acceleration whose perceptibility was demonstrated by tests conducted in active touch conditions. The two experiments confirm that piano performers perceive vibratory cues of strings mediated by spectral and spatial summations occurring in the Pacinian system in their fingertips, and suggest that such cues play a role in the evaluation of quality of the musical instrument.
A time-domain model for seafloor scattering
Authors: Tang Dajun , Jackson Darrell
Published: November 2017

Bottom scattering is important for a number of underwater applications: it is a source of noise in target detection and a source of information for sediment classification and geoacoustic inversion. While current models can predict the effective interface scattering strength for layered sediments, these models cannot directly compute the ensemble averaged mean-square pressure. A model for bottom scattering due to a point source is introduced which provides a full-wave solution for mean-square scattered pressure as a function of time under first-order perturbation theory. Examples of backscatter time series from various types of seafloors will be shown, and the advantages and limitations of this model will be discussed.
Consistency and accountability: First steps in a quest for compromise between venue and community
Authors: Reuter Eric L.
Published: November 2017

This case study examines the first steps in reducing several years of tension between an active outdoor venue, with more than 60 performances each summer, and the surrounding community in a small coastal city in New Hampshire. Continuous sound level monitoring and realtime visual feedback provide means of achieving consistent (though somewhat arbitrary) sound levels throughout and across performances, thus eliminating a variable in the evaluation of impacts on the community. Sound level data, along with feedback from the community, will be used to develop mitigation strategies for future seasons. Details of the monitoring and feedback systems and lessons learned from the 2017 season will be shared.