bluuebunny/crossref_metadata_2025 huggingface dataset:
The Impacts of Eco-Tourism and Agrotourism Based on Plant Variety Protection to Sustain Biological Diversity and Green Economic Growth in Indonesia
Authors: Wartini Sri , Alfaqiih Abdurrahman , Riswandi Budi Agus , Park Jihyun
Published: December 2022

Ecotourism and agrotourism have contributed to green economic development as well as to the development of plant variety protection. Agrotourism is a form of commercial enterprise that links agricultural production and/or processing with tourism to attract visitors to a farm or other agricultural businesses for recreation, entertainment, or education for visitors and to generate income for the farm or the business owner. Ecotourism encompasses nature-based activities that increase visitor appreciation and understanding of natural and cultural values. In order to encourage the community and business owners to participate in eco-tourism and agrotourism, it is imperative to protect plant variety as one of the regimes of intellectual property rights. The aim of the research is to analyze the impacts of ecotourism and agrotourism based on plant variety protection contributing to the sustainability of biodiversity and green economic growth in Indonesia comprehensively. This research is normative juridical research by employing conceptual and statutory approaches. The result of the research found that enhancing ecotourism and agrotourism based on plant variety protection can sustain and enrich biodiversity achieving green economic growth in Indonesia. However, there are some achievements and challenges that have to be addressed, such as the harmonization of the regulations, encouragement of the community and business owner participation in ecotourism and agrotourism by creating a new variety of plants to enhance biodiversity to achieve green economy development in Indonesia.
EVIDENCE IN THE INTERNATIONAL CRIMINAL COURT – THE ROLE OF FORENSIC EXPERTS: THE UKRAINIAN CONTEXT
Authors: Kaluzhna Oksana
Published: December 2022

Background: Ukraine faced unprecedented challenges for to the national justice system and the possibility of using international justice to bring the Russian Federation military, officers,and officials to justice after the full-scale invasion of Ukraine by the Russian Federation on 24 February 24, 2022. Since In March 2022, the ICC Prosecutor has started an investigation of into war crimes in Ukraine. In addition, joint investigative groups are carrying out activities. Cooperation between pre-trial investigation bodies of Ukraine through the Prosecutor General of Ukraine with and the International Criminal Court has been established. Therefore, the research of into possible problems in the criminal procedure of prosecution for war crimes is one of the priority areas for Ukrainian law enforcement practice and legal science.
Methods: The present article is devoted to the peculiarities of the ICC international criminal justice, in particular the ICC jurisdiction in the territory of Ukraine (Ukraine has not ratified the ІСС Rome Statute), the ICC model of administration of justice, the rules of admissibility of evidence, the status of experts, and the features of expert involvement during ICC trials.
Results and Conclusions: The authors found that several provisions of the joint Order of the Ministry of Internal Affairs of Ukraine, the Ministry of Health of Ukraine, and the Office of the Prosecutor General ‘On approval of the Procedure for interaction between bodies and units of the National Police of Ukraine, health care institutions and the bodies of the Prosecutor’s Office of Ukraine in establishing the fact of the death of a person during martial law on the territory of Ukraine’ dated 9 March 2022 do not correspond to the Code of Criminal Procedure of Ukraine. The authors emphasise that the erroneous provisions of this bylaw could serve as a legal basis for avoiding criminal responsibility for war crimes.
UNAMENDABLE PROVISIONS OF THE CONSTITUTION AND THE TERRITORIAL INTEGRITY OF UKRAINE
Authors: Berchenko Hryhorii , Slinko Tetiana , Horai Oleh
Published: December 2022

Background: Unamendable constitutional provisions arose with the appearance of the first constitutions in the USA and Norway, but did not become widespread. The unamendability of a republican form of government, included in the Constitution of France in 1885, continued this tradition. Such provisions became more widespread after the Second World War. Countries that gained independence began to include a mention of territorial integrity in such provisions. Ukraine belongs to such countries (the Constitution of 1996). Since 2014, Ukraine has faced encroachment on its territorial integrity by an aggressor state − its eastern neighbor. Given these circumstances, the study of the nature and meaning of unamendable provisions of a constitution has particular relevance. Methods: The following methods were used in the work to research the main approaches to the unamendable provisions of the constitution. The system-structural method was useful when providing a structural characterisation of the concept of unamendable provisions, as well as its varieties, establishing a relationship with other concepts (multilevel constitutional design). The logical-legal method made it possible to discover the positions of scientists regarding an optimal list of unamendable provisions, the possible violation of such provisions in the situation of a constitutional revolution, and the positions of the Constitutional Court of Ukraine regarding the protection of territorial integrity in Ukraine. The comparative method was used to study the experience of foreign countries. Results and Conclusions: The paper analysed the legal consequences of violation of territorial integrity, concluding that military aggression, occupation and unacknowledged annexation of part of Ukrainian territory by Russia is not a reason to refuse territorial integrity as an unamendable provision of the Constitution of Ukraine. On the contrary, the protection of this provision should be strengthened.
Pengaruh Korosi Tulangan Secara Alami pada Balok Beton Bertulang Terhadap Kuat Lentur dan Geser
Authors: Mulyadi Anggi Ahmad , Walujodjati Eko
Published: December 2022

Dalam pengaplikasian di lapangan, beton sering digunakan sebagai elemen struktur, salah satunya sering dibuat balok beton yang dikombinasikan dengan tulangan baja. Balok beton bertulang peranannya cukup besar untuk menahan beban, terutama beban lentur dan geser. Balok Beton yang memiliki kemampuan menahan gaya lentur dan geser secara maksimal .Bahan-bahan penyusun beton bertulangnya yaitu khususnya tulangan baja, banyak mengalami korosi sebelum digunakan, akibat penyimpanan yang tidak baik .Pengkorosian tulangan dilakukan ditempat terbuka terkena cahaya matahari,air hujan,suhu dan kelembaban selama 4 bulan. Selanjutnya dilaksanakan pengujian kuat tekan beton dengan umur 28 hari rata- rata 17,78 MPa,kuat tarik tulangan tidak korosi  8 (ø) 530.12 mpa,tulangan  korosi  8 (ø) 517.52 mpa ,tulangan tidak korosi  10 (ø) 586.84 mpa,tulangan korosi  10 (ø) 569.00 mpa. Balok beton dengan tulangan korosi beban puncak rata -rata pada alat uji lebih tinggi 55,4 KN dari balok beton dengan tulangan tidak korosi 44,6 KN. Nilai momen kuat lentur rata -rata balok tulangan korosi adalah 4,85 KNm dan nilai momen kuat lentur rata -rata balok tulangan tidak korosi adalah 3,90 KNm ,nilai tegangan balok tulangan korosi rata - rata  adalah 6,92 MPa, dan untuk balok tulangan tidak korosi adalah 5.53 MPa. Untuk nilai geser balok beton bertulang tidak korosi lebih besar dari pada balok beton bertulang korosi. Balok beton dengan tulangan tidak korosi lebih besar 90,15 KN dari pada balok beton dengan tulangan  korosi  88,33 KN.
Pengaruh Korosi Tulangan Terhadap Panjang Penyaluran pada Beton
Authors: Anjani Widianti Sri , Walujodjati Eko
Published: December 2022

Beton bertulang merupakan dua bahan yang terdiri dari baja tulangan dan beton yang digunakan secara bersama. Tulangan baja harus mempunyai tegangan rekat yang sama dengan komponen beton yang mengelilinginya sehingga antara kedua bahan harus ada kuat lekat. Tulangan yang dipakai harus dalam keadaan baik dan tidak terkorosi. Tujuan penelitian ini yaitu untuk mengetahui perbandingan nilai kuat lekat berdasarkan panjang penyaluran antara tulangan korosi dan tulangan tidak korosi menggunakan baja tulangan diameter 10 mm dengan tulangan polos. Metode yang dipakai dalam penelitian ini yaitu metode eksperimental (percobaan) yang dilaksanakan di Laboratorium Teknik Sipil. Pengkorosikan tulangan dilakukan dengan cara laju korosi pada temperatur udara terbuka dimana tulangan di posisikan menerima udara bebas. Pada penelitian ini menggunakan 9 sampel benda uji menggunakan tulangan korosi, dan 9 sampel benda uji menggunakan tulangan tidak korosi. Pengujian kuat lekat dilakukan dengan cara uji pull-out test, dimana baja tulangan ditarik keluar (pull out) sampai terjadi slip atau sampai timbul retak pada beton. Tegangan lekat rata-rata tulangan korosi dengan panjang penyaluran 150 mm sebesar 3,808 Mpa sedangkan tulangan tidak korosi 4,137 Mpa. Tegangan lekat rata-rata tulangan korosi dengan panjang penyaluran 100 mm sebesar 3,66 Mpa sedangkan tulangan tidak korosi 4,222 Mpa. Tegangan lekat rata-rata tulangan korosi dengan panjang penyaluran 50 mm sebesar 7,363 Mpa sedangkan tulangan tidak korosi 6,684 Mpa. Pada tulangan korosi terjadi penurunan panjang penyaluran dari 150  mm ke 100 mm namun terjadi peningkatan pada 50 mm. Sedangkan tulangan tidak korosi terjadi peningkatan panjang penyaluran dari 150 mm, 100 mm, hingga 50 mm.
Analisis Hidrologi Perencanaan Embung Bratayudha
Authors: Rustini Ai , Permana Sulwan
Published: December 2022

Kabupaten Garut merupakan salah satu daerah yang berada di Provinsi Jawa Barat yang beriklim tropis basah, hal ini menyebabkan curah hujannya cukup tinggi sehingga terdapat beberapa lokasi yang sering mengalami luapan air yang tinggi atau biasa disebut banjir. Pembangunan embung merupakan langkah yang bisa diambil dalam penanganan banjir yang terjadi di salah satu daerah di Garut yaitu Jl. Bratayudha. Tujuan dari penelitian ini yaitu menentukan tipe embung yang cocok dengan tempat perencanaan serta menetukan kapasitas tampungan embung tersebut dengan menggunakan metode perhitungan analisis hidrologi yang meliputi hujan rencana dengan menggunakan Distribusi Normal, Log Normal 2 dan 3 parameter, Gumbel tipe I dan Log Pearson tipe III. Volume embung ditentukan dengan luasan genangan embung berdasarkan elevasi data kontur pada peta topografi. Tahap terakhir adalah menentukan material konstruksi. Hasil perencanaan Embung Bratayudha mempunyai luas 6480 m² dengan volume maksimum 15.552 m³ dan elevasi maksimum 40,4 + m. Untuk tubuh embung direncanakan berupa dinding turap batu kali yang dilapisi oleh bahan kedap air dan dikombinasikan dengan  beton bertulang. Embung Bratayudha ini diharapkan dapat memenuhi kebutuhan pengairan lahan pertanian warga. Selain itu, letak embung yang berada pada level muka tanah yang tinggi dan pemandangan alam yang elok, diharapkan dapat menjadi obyek pariwisata baru di Kabupaten Garut.
Clinical Significance of Torsion Measured by Fundus Photography in Children
Authors: Lee Seungheon , Choi Mi Young
Published: December 2022

Purpose: To investigate the clinical significance of ocular torsion in children by analyzing the associated ophthalmic diseases.Methods: Fundus images were used to detect ocular torsion in one or both eyes of 83 children aged 2-12 years at a pediatric ophthalmology clinic. In cases with ocular torsion, associated ophthalmic diseases, including strabismus, amblyopia, and refractive errors, were investigated.Results: Among the 83 patients, 59 (71.2%) and 45 (54.2%) had strabismus and refractive errors, respectively. Six had amblyopia (five patients with refractive amblyopia and one with strabismus), while six patients (7.2%) had no strabismus, refractive errors, or amblyopia. The extorsion group included 80 eyes in 59 patients, while the intorsion group included 26 eyes in 22 patients. Two patients were in the mixed cyclotorsion group with extorsion in one eye and intorsion in the other eye. There were no differences in the frequencies of exotropia and esotropia based on the torsion type (p = 0.209). The torsion angles in the exotropia and esotropia groups were -16.35 ± 5.20 and -12.71 ± 3.16, respectively (p = 0.002).Conclusions: Children with ocular torsion on fundus photography had a high prevalence of strabismus. Extorsion was more frequent than intorsion with a greater extorsion angle in exotropia than in esotropia.
Epithelial Myoepithelial Carcinoma of the Hard Palate: A Case Report with a Review of the Literature
Authors: Palaniappan Ravisankar , Chandran Jayanthi , Purushothaman Damodarakumaran , Nandhagopal Vijayaraghavan
Published: December 2022

Background: Epithelial myoepithelial carcinoma (EMC) is a rare biphasic tumour of the salivary gland with two cell types of inner ductal cells and outer layer of clear cells. In the literature, there are only a few reports of EMC originating from the hard palate. Case report: A 58-year-old female presented to the authors’ institution with partially submucosal lesion in the posterior aspect of the hard palate on the left side for 1 month. Biopsy was suggestive of a multinodular tumour with round to oval cells and a moderate number of pale eosinophilic to clear cytoplasm and round to oval, centrally to eccentrically placed, mildly pleomorphic vesicular nuclei suggestive of EMC of the hard palate. Immunohistochemically, cytokeratin (CK 5/6) showed strong cytoplasmic positivity highlighting the luminal epithelial cells. The myoepithelial cells showed strong nuclear positivity for p63 and cytoplasmic positivity for calponin. The patient underwent surgical resection of the tumour with a local flap cover and split skin graft and all the margins were negative in the final histopathological examination with erosion of the underlying bone. The patient was kept under observation and has been free of the disease for the past 12 months. Conclusion: Diagnosis of EMC is rare and is to be kept as a differential diagnosis during the evaluation of minor salivary gland tumours of palate.
Investigasi Energi Termal pada Mesin Diesel Tipe SULZER ZAV 40S dengan Bahan Bakar Marine Fuel Oil (MFO)
Authors: Marcelina Marcelina , Khairi Syahrul , Kurniawan Eddy , P Yolanda Kristina Desideria
Published: December 2022

Studi enegi termal yang dihasilkan oleh mesin diesel tipe Sulzer ZAV 40S  menggunakan bahan bakar Marine Fuel Oil (MFO) dapat mempengaruhi proses pembakaran mesin karena adanya perubahan energi bahan kimia bahan bakar menjadi kerja internal. Energi panas yang dihasilkan di dalam mesin diesel dimana proses penyalaannya saat piston mendekati titik mati kemudian dilanjutkan oleh adanya bahan bakar yaitu MFO. Bahan bakar tersebut akan disemprotkan melalui nozel ke dalam ruang bakar. Hal ini akan terjadi proses pembakaran sempurna dimana komposisi massa udara dan bahan bakar di dalam silinder akan menimbulkan panas karena suhu yang tinggi. Hasil perhitungan yang kebutuhan bahan bakar dan udara untuk menghasilkan nilai energi (Q) dari mesin diesel ini adalah 808,33 Kcal dan dayanya (Ni) sebesar 4.602,09 PK dalam setiap detik sedangkan massa MGO sebanyak 5 Kg dan udara sebesar 130 Kg dalam setiap menit untuk putaran 500 rpm secara kontinyu.
Simulasi Model Evakuasi Bencana Kebakaran Pemukiman Pesisir
Authors: Sandana Aprilla Warlisia
Published: December 2022

The poor setting out of coastal settlements had very high vulnerability of the fire hazard. The limited access caused difficulties in evacuating the community (agents) when fire was accured. The communities as agents in a group interaction activities due to the environment had evacuation path and other support systems to find the fastest way out. This research had designed a simulation model of community movement during a fire disaster in the coastal settlement. The case study of this research was defined in the dense coastal settlement area of Pasar ​​Batu Tarakan, North Kalimantan. The community evacuation simulation used the Agent Based Modeling (ABM) utilized NetLogo software. The survey was conducted by considering the condition of main route that can be accessed. The modeling had 3 simulation scenarios were based on the number of agents movement who left the fire site. The double linear regression had been utilized to analyze the variable correlation. The results showed a scenario 3 had the largest people number who passed out the exit way. The selection of the path was based on the distance and route width on the number of people save had very significant correlation (R2 = 98,34%).
Perencanaan Bahan Baku OM-Chips Untuk Produk Film G2 Menggunakan Metode Peramalan Dan Metode EOQ
Authors: Efendi Murzid , Juhara Sutresna , Khamaludin Khamaludin
Published: December 2022

PT. INDONESIA TOYOBO FILM SOLUTIONS merupakan industri yang memproduksi plastik lembaran / Film jenis PET. Pada perusahaan ini mengalami penumpukan bahan baku jenis OM-Chips untuk produk Film G2. Pada penelitian akan menerapkan Metode Peramalan Moving Average dan Exponential Smoothing, dan untuk perencanaan bahan bakunya menggunakan Metode Economic Order Quantity. Apakah metode EOQ ini mampu ongkos persediaan bahan baku tersebut sehingga dapat meminimalkan ongkos persediaan bahan baku juga dapat diketahui hasilnya nanti. Untuk peramalan didapatkan hasil bahwa metode peramalan Moving Average 2 bulanan memiliki nilai MAD = 19,5 dan MAPE = 13,58. Untuk biaya persediaan perusahaan pada periode Agustus 2020-Juli 2021 tanpa menggunakan metode EOQ yaitu sebesar Rp. 45,499,623. Dan setelah menggunakan metode EOQ pada periode Agustus 2020-Juli 2021 didapatkan hasil biaya persediaan sebesar Rp. 36,252,000. Terjadi penurunan biaya persediaan pada periode Agustus 2020-Juli 2021 sebesar 11.31%. Sedangkan untuk persediaan bahan baku untuk periode yang akan datang Agustus 2021-Juli 2022 menggunakan metode EOQ untuk jumlah pembelian ekonomis setiap kali pesan yaitu sebesar 93.81 Ton, dengan frekuensi pembelian sebanyak 19 kali. Dan untuk persediaan pangaman (Safety Stock) sebesar 41.44 Ton dengan nilai Re-Order Point yaitu sebesar 246.78. Dari hasil perhitungan tersebut didapatkan untuk biaya persediaan periode Agustus 2021-Juli 2022 sebesar Rp. 28,141,500.
Ultrastructural Characteristics of Axodendritic and Axosomatic Synapses in the Orbitofrontal Cortex of White Laboratory Rats Associated with Low-Protein Food after Acute Sound Exposure
Authors: Sultanly M. E.
Published: December 2022

This paper investigates the state of axodendritic (ADS) and axosomatic (ASS) synapses in orbitofrontal cortex (OFC) layers I-IV of adult white laboratory rats associated with balanced and low-protein food after acute sound exposure. Experiments were performed on 64 white non-linear sexually mature laboratory male rats weighing 180–230 g (eight intact, 56 experimental). After a continuous call with an intensity of 120 db for 120 seconds, 56 rats were divided into two groups: those receiving balanced (control – 28) and low-protein food (basic – 28). Each of these two groups was divided into two subgroups: stress-resistant (12 animals in each) and stress-unstable animals (16 animals in each). Water intake was unlimited. The animals were removed from the experiment on the 10th, 20th, 30th, and 40th day after sound exposure. Along with histological and immunohistochemical analysis, the samples of OFC layers I–IV were studied by transmission electron microscopy. Electron microscopic changes in the structure of ADS and ASS were found in all OFC layers. Violations of the fine structure of both the presynaptic and postsynaptic poles were noted. The maximum severity of ultrastructural changes was observed in the ADS of the surface (I, molecular), outer granular (II), pyramidal (III), and inner granular (IV) OFC layers. ASS disorganization was noted mainly in contacts, the postsynaptic pole of which was formed by the bodies of small pyramidal neurons of layer III, as well as pyramidal and stellate neurons of layer IV of the OFC. During all periods of observation, violations of fine organization were most pronounced in stress-unstable animals of the main experimental group, especially on the 10th and 20th day after exposure. Acute sound exposure initiates disturbances in the fine organization of axodendritic and axosomatic synapses in OFC layers I–IV of white laboratory rats. Focal destruction of a part of the noted synapses in rats with a low-protein diet after acute auditory stress is irreversible.
Interpretation of NSDD and Restrike in Capacitive Current Switching Test on Medium Voltage Vacuum Circuit Breaker
Authors: Venkateswarlu G. , Agarwal Yugal , Takkher M. S. , Wadhwani M. K. , Mehra B. M.
Published: December 2022

Capacitor banks are installed in an increasing number to control power quality issues and improving the power factor tocounteract the reactive power in the transmission and distribution networks. Due to load fluctuations switching of capacitorbanks is a typical phenomenon. Capacitor bank is normally having concentrated capacitance in contrast with distributedcapacitance. It generally draws more current than unloaded cableor line in practical cases up to several hundred amperes.Hence, switching of capacitor bank causes a very high rate of rise of transient recovery voltage across circuit breakercontacts. This scenario can be simulated in testing laboratories by a voltage source connected to a circuit breaker whichagain is connected to a large capacitance in terms of IEC called capacitive current switching test. Non-sustained disruptivedischarge (NSDD) is a voltage breakdown after the vacuum circuit-breaker open the fault current which will not cause therecovery of power frequency current. Restrike is different from NSDD, the recovery of power frequency current betweenthe contacts will make the breaker failed. It’s not easy to show the distinction between NSDD and restrike during some typetests. The paper presents the study of performance evaluation of the circuit breaker during the capacitor current switchingduties. A statistical analysis of failure of circuit breaker during capacitor current switching tests are included in the paperto help the manufacturers & utilities, so that the care can be taken for trouble free services. The paper also discusses thechanges made in the IEC 62271 – 100, Amendment1:2012 for conducting the capacitive current switching tests.
Protection — Evolution, Technologies and Trends
Authors: Shah Vijay
Published: December 2022

Industrial growth with increased automation has made electricity as the key resource for the modern society. Electricpower in today’s context has assumed importance as necessity of life next to food, shelter and clothes. This also impliesthat all elements of entire chain of power generation, transmission and distribution needs to offer fail safe performanceat all instance of time, and in case of any unforeseen faults, are required not only to provide effective protection to powersystem elements and isolate the fault but also ensure continuity of electric supply for rest of network, by ensuring veryminimal region/loads over faulted section remains without power. Power system protection hence remains one of the mostcomplex discipline in electrical engineering. Protective relays are the decision-making devices in the protection scheme.These relays have undergone, through more than a century, important changes in their architecture, functionalities andtechnologies. In this paper, after giving insight on the evolution of protective relays from onset of electrical energy tocurrent deployment, emerging trends are also touched upon. Specific emphasis on very recent deployment of CentralizedProtection and Control solution is then described. Finally, future trends are also highlighted at the end.
Effect of Roof Height on Internal Arc Testing of Switchgear Panels
Authors: Chennu Rajaramamohanarao , Reddy S. Sudhakara , Awasthi Anupam , Maroti Gurudev T. , Kumar S. Arun , Sreeram V.
Published: December 2022

The market requirements for Medium Voltage (MV) metal enclosed switchgear are getting more and more stringent. Bothbuilding costs as well as the level of the transmitted and distributed electrical power have increased rapidly over the recentyears and are expected to continue to rise. This means that switchgear manufacturers must bring more and more compactand powerful systems on the market, while being simultaneously as cost effective as possible. Internal Arc Classification(IAC) of switchgear according to IEC and IEEE standards is one of the most important requirements to guaranteesafety in case of internal arc faults. Internal arcs cause a sudden pressure rise in electrical installations. This leads to anextreme pressure stress acting on switchgear compartments and switchgear rooms and could cause collapse of buildingsThis paper describes few important design rules and innovations, which were necessary to achieve best results duringinternal arc tests. Furthermore it demonstrates the effect of roof height during the internal arc test with the important casestudies. Finally the best solution to eliminate the roof effect is also proposed.
Characteristics of the HGI Fractions of the Indian Coal Blended with Imported Coals
Authors: Arunkumar K. H. , Saravanan V.
Published: December 2022

The blends of a high ash Indian coal with three coals of different foreign origins -Australia, Russia and Indonesia weresubjected to HGI testing as per ASTM D 409 and the resulted fractions obtained in the coarser and finer portions of ASTM200 mesh (75 microns) were assessed for their characteristics in respect of proximate and ultimate parameters, alphaquartz and combustion reactivity. The similar studies were also carried out for the parent coals. HGI values were foundadditive in case of Indian-Indonesian coal blends and the same was found non-additive in respect of Indian-Russian andIndian-Australian coal blends. Considerable variation in properties was observed in the coarser and finer fractions of theASTM 200 mesh for parent Indian and Indonesian coals compared to parent Australian and Russian coals. This indicatesthe disproportion of the coals and coal blends particles during the sieving process after subjecting to HGI test. The variationof alpha quartz content in the coarser and finer fractions indicate that there is a segregation of free minerals in the coarserand finer fractions. The conversion plots obtained through TGA for the coarser and finer fractions indicate that there is nomaceral segregation.
PENGARUH MASSAGE PUNGGUNG TERHADAP KELANCARAN ASI PADA IBU POSTPARTUM DENGAN SECTIO CAESAR
Authors: Putra Farhandika , Rukayah Siti
Published: December 2022

Mothers who give birth with SC are 3 times more likely to experience obstacles in the breastfeeding process than normal births. WHO establishes a 5-15% SC delivery indicator for each country, if it does not match the indications SC surgery can increase the risk of morbidity and mortality in the mother and baby. One of the efforts to stimulate the hormone prolactin and oxytociny which is very instrumental in the smoothness of ASI is back massage. The aim of this study was to determine the effect of back massage on the smoothness of breast milk in postpartum mothers with SC. This study was a quasi-experimental method with a pretest and posttest without control group design. The sample in this study were 11 patients with accidental sampling technique. An instrument used is the smoothness of ASI queationnaire sheet.  The results of this study there before do back massage to smoothness of ASI. were (100%) respondents experiencing non-smooth breastfeeding and after do back massage to smoothness of ASI. were (88.1%) respondents experienced smooth breastfeeding, the result of this study was wicoxon signed rank test obtained p value of 0.004 (<0.05). The conclusion of this study, that there was an effect of back massage on the smoothness of breast milk in postpartum mothers with SC. It was suggested

Ibu-ibu yang melahirkan dengan SC beresiko 3 kali lebih besar untuk mengalami hambatan dalam proses menyusui dibandingkan lahir normal. WHO menetapkan indikator persalinan SC 5-15% untuk setiap negara, jika tidak sesuai indikasi operasi SC dapat meningkatkan resiko morbiditas dan mortalitas pada ibu dan bayi. Salah satu usaha untuk merangsang hormon prolaktin dan oksitosinyang sangat berperan dalam kelancaran ASI adalah massage punggung. Tujuan penelitian ini untuk mengetahui pengaruh massage punggung terhadap kelancaran ASI pada ibu postpartum dengan SC. Penelitian ini menggunakan metode quasi-experimental dengan rancangan pretest dan posttest without control group design. Sampel dalam penelitian ini adalah11 pasien dengan teknik pengambilan sampelaccidental sampling. Instrumen dalam penelitian ini yaitu kuesioner kelancaran ASI. Hasil penelitian ini sebelum dilakukan massage punggung responden yang mengalami ASI tidak lancar sebanyak (100%) dan setelah dilakukan massage punggung responden ysng mengalami ASI lancar sebanyak (81,8%). Hasil uji wicoxon signed rank test didapatkan nilai P value 0,004(<0,05) H0 ditolak Ha diterima. Kesimpulan dari penelitian ini adalah ada pengaruh massage punggung terhadap kelancaran ASI pada ibu postpartum dengan SC. Disarankan kepada responden untuk rutin melakukan massage punggung untuk meningkatkan kelancaran ASI.
PERILAKU CARING PERAWAT DI RUANG RAWAT INAP DI RUMAH SAKIT SUAKA INSAN BANJARMASIN 2020
Authors: Chrisnawati Chrisnawati , Lima Maria Cardoso , Trihandini Bernadeta , Maratning Anastasia
Published: December 2022

Latar Belakang: Pada era globalisasi, tuntutan masyarakat terhadap pelayanan kesehatan yang memadai semakin meningkat dan memacu rumah sakit untuk memberikan layanan terbaik agar tidak dimarginalkan oleh masyarakat. Caring sebagai dasar dan sentral dalam praktek keperawatan. Manfaat Caring sangat penting dalam pemberian pelayanan keperawatan yang didasari oleh perilaku caring perawat mampu meningkatkan kualitas pelayanan kesehatan.Transpersonal caring mengakui kesatuan dalam hidup dan hubungan-hubungan yang terdapat dalam lingkaran caring yang konsentrik dari individu, pada orang lain, pada masyarakat, pada dunia, pada bumi dan pada alam semesta. Tujuan: Untuk mengetahui “Bagaimana Gambaran Perilaku Caring Perawat di Ruang Rawat Inap di Rumah Sakit Suaka Insan Banjarmasin Tahun 2020”. Metode : Penelitian ini menggunakan metode deskriptif kuantitatif. Sampelnya adalah seluruh pasien yang berjumlah 95 responden .Alat ukur berupa kuesioner.Analisa univariat dengan distribusi frekuensi.Teknik sampling dengan Purposive sampling. Hasil : Berdasarkan hasil penelitian diperoleh (1) Karakteristik responden berdasarkan jenis kelamin mayoritas adalah perempuan  (52,6 %), (2)  berdasarkan usia mayoritas usia 31-50 tahun (41 %), (3) berdasarkan tingkat pendidikan adalah mayoritas SMA (49,4 %), (4) berdasarkan rasa hormat adalah baik (62%), (5) berdasarkan kehadiran adalah baik (62%), (6) berdasarkan hubungan yang positif adalah baik (79%), (7) berdasarkan memiliki pengetahuan dan ketrampilan yang professional adalah baik (85%), (8) berdasarkan perhatian dengan pengalaman orang lain adalah baik ( 94 %), (9) berdsarkan keseluruhan  kategori adalah baik (71%). Kesimpulan : Gambaran Perilaku Caring Perawat di Ruang Rawat Inap di Rumah Sakit Suaka Insan Banjarmasin 2020 adalah baik (71%) dan diharapkan perawat dapat mempertahankan dan meningkatkan kualitas pelayanan dalam perilaku caring.
PENGALAMAN PERAWAT YANG PERNAH TERKONFIRMASI COVID-19 DI RSUD SULTAN SURIANSYAH
Authors: Sundari Sri , Harun Lukman
Published: December 2022

Latar Belakang: Tingginya angka kejadian COVID-19 yang menyebabkan menjadi pandemi untuk seluruh dunia, bahkan Indonesia, Kalimantan Selatan menyumbang angka yang cukup besar terkait penyakit COVID-19, yaitu salah satunya adalah tenaga kesehatan, salah satunya adalah perawat, perawat adalah orang yang semakin banyak berinteraksi dengan pasien di Rumah Sakit, sehingga perawat juga lumayan banyak yang telah terinfeksi atau terkonfirmasi COVID-19. Tujuan: memperoleh gambaran tentang pengalaman perawat yang pernah terkonfirmasi COVID-19 di RSUD Sultan Suriansyah.

Metode: yang digunakan dalam penelitian ini adalah metode kualitatif dengan desain fenomenologi. Pengumpulan data dilakukan dengan wawancara mendalam pada sepuluh orang partisipan. Pengumpulan data dilakukan dengan wawancara mendalam pada sepuluh orang perawat yang pernah terkonfirmasi COVID-19 di RSUD Sultan Suriansyah. Analisis data menggunakan teknik Collaizzi’s. Hasil: yaitu: (1) pemahaman tentang COVID-19; (2) tanda gejala COVID-19 (3) proses penularan COVID-19; (4) Penetapan Diagnosa Terkonfirmasi COVID-19; (5) respon tubuh setelah tahu terkonfirmasi COVID-19; (6) Tindakan setelah tahu terkonfirmasi COVID-19; (7) Harapan setelah dinyatakan sembuh.

Kesimpulan: Penglaman perawat dalam penelitian ini adalah penyakit akibat virus corona yang mnegenai sistem pernafasan, pencernaan, gangguan rasa nyaman dan sistem imun tubuh manusia yang cepat sekali menularkan kepada orang lain sehingga menuntut kita untuk menjaga protokol kesehatan. Supaya lebih meperhatikan protokol kesehatan baik di rumah maupun di rumah sakit.
Hubungan Health Locus of Control Terhadap Tingkat Kepatuhan Kontrol Glikemik Pada Pasien Diabetes Melitus Tipe 2 di Puskesmas Terminal Banjarmasin
Authors: Manto Onieqie Ayu Dhea , Naim Rico , Tjomiadi Cynthia Eka Fayuning
Published: December 2022

Latar Belakang: Diabetes melitus adalah salah satu penyakit kronis yang disebabkan karena pankreas tidak dapat menghasilkan insulin yang cukup untuk tubuh. Salah satu pilar pengobatan diabetes melitus adalah kontrol glikemik dengan health locus of control yang jarang disadari dalam proses pengendalian. Tujuan: Mengetahui hubungan antara health locus of control terhadap tingkat kepatuhan kontrol glikemik pada pasien diabetes melitus tipe 2 di Puskesmas Terminal Banjarmasin. Metode: Penelitian ini menggunakan metode kuantitatif dan menggunakan pendekatan studi cross sectional. Jumlah sampel sebanyak 73 orang dengan teknik purposive sampling. Hasil: Hasil uji korelasi Spearman’s rho dengan α = 0,05. Dari hasil uji statistik Spearman’s rho didapatkan nilai signifikan 0,198 > 0,05 menunjukkan tidak ada hubungan antara health locus of control terhadap tingkat kepatuhan kontrol glikemik. Kesimpulan: Kepatuhan tidak hanya di pengaruhi oleh health locus of control tetapi juga dipengaruhi oleh faktor lain seperti pemberian obat-obatan, pola diet, aktivitas fisik ataupun foot care (perawatan kaki)
Targeted in vitro gene silencing of E2 and nsP1 genes of chikungunya virus by biocompatible zeolitic imidazolate framework
Authors: Tagore Rajarshee , Alagarasu Kalichamy , Patil Poonam , Pyreddy Suneela , Polash Shakil Ahmed , Kakade Mahadeo , Shukla Ravi , Parashar Deepti
Published: December 2022

Chikungunya fever caused by the mosquito-transmitted chikungunya virus (CHIKV) is a major public health concern in tropical, sub-tropical and temperate climatic regions. The lack of any licensed vaccine or antiviral agents against CHIKV warrants the development of effective antiviral therapies. Small interfering RNA (siRNA) mediated gene silencing of CHIKV structural and non-structural genes serves as a potential antiviral strategy. The therapeutic efficiency of siRNA can be improved by using an efficient delivery system. Metal-organic framework biocomposits have demonstrated an exceptional capability in protecting and efficiently delivering nucleic acids into cells. In the present study, carbonated ZIF called ZIF-C has been utilized to deliver siRNAs targeted against E2 and nsP1 genes of CHIKV to achieve a reduction in viral replication and infectivity. Cellular transfection studies of E2 and nsP1 genes targeting free siRNAs and ZIF-C encapsulated siRNAs in CHIKV infected Vero CCL-81 cells were performed. Our results reveal a significant reduction of infectious virus titre, viral RNA levels and percent of infected cells in cultures transfected with ZIF-C encapsulated siRNA compared to cells transfected with free siRNA. The results suggest that delivery of siRNA through ZIF-C enhances the antiviral activity of CHIKV E2 and nsP1 genes directed siRNAs.
Efficacy and safety of stem cell therapy in cerebral palsy: A systematic review and meta-analysis
Authors: Qu Jiayang , Zhou Lin , Zhang Hao , Han Dongmiao , Luo Yaolin , Chen Junming , Li Lincai , Zou Zhengwei , He Zhengyi , Zhang Minhong , Ye Junsong
Published: December 2022

Aim: Although the efficacy and safety of stem cell therapy for cerebral palsy has been demonstrated in previous studies, the number of studies is limited and the treatment protocols of these studies lack consistency. Therefore, we included all relevant studies to date to explore factors that might influence the effectiveness of treatment based on the determination of safety and efficacy.

Methods: The data source includes PubMed/Medline, Web of Science, EMBASE, Cochrane Library, from inception to 2 January 2022. Literature was screened according to the PICOS principle, followed by literature quality evaluation to assess the risk of bias. Finally, the outcome indicators of each study were extracted for combined analysis.

Results: 9 studies were included in the current analysis. The results of the pooled analysis showed that the improvements in both primary and secondary indicators except for Bayley Scales of Infant and Toddler Development were more skewed towards stem cell therapy than the control group. In the subgroup analysis, the results showed that stem cell therapy significantly increased Gross Motor Function Measure (GMFM) scores of 3, 6, and 12 months. Besides, improvements in GMFM scores were more skewed toward umbilical cord mesenchymal stem cells, low dose, and intrathecal injection. Importantly, there was no significant difference in the adverse events (RR = 1.13; 95% CI = [0.90, 1.42]) between the stem cell group and the control group.

Conclusion: The results suggested that stem cell therapy for cerebral palsy was safe and effective. Although the subgroup analysis results presented guiding significance in the selection of clinical protocols for stem cell therapy, high-quality RCTs validations are still needed.
A semi-active control system in coupled buildings with base-isolation and magnetorheological dampers using an adaptive neuro-fuzzy inference system
Authors: Tai Wei Chun , Ikenaga Masahiro
Published: December 2022

Connecting two buildings has been proved as an effective method of structural control for alleviating seismic responses. Researchers have proposed that two adjacent buildings through supplemental energy dissipating devices to mitigate the buildings’ responses. Numerous researchers have proposed various methods: active, passive, and semi-active control strategies. In Japan, some applications of coupled buildings control have been successfully implemented by utilizing passive and active control technology. Magnetorheological (MR) dampers have been identified as semi-active devices that can be used to reduce the vibration of the seismic structures during various types of ground motions. They can offer the adaptability of active devices, stability, and reliability of passive devices. Nevertheless, one of the difficulties in application of the MR dampers is the development of the appropriate control algorithms. Accordingly, this study presents the implementation of the adaptive neuro-fuzzy inference system (ANFIS) controller for earthquake hazard mitigation under coupled buildings control system with base-isolated building connecting to the free wall by MR dampers. The ANFIS whose training data is based on the Linear Quadratic Regulator (LQR) method is conducted to modify the parameters of the fuzzy logic controller and optimize the fuzzy rules. The performance of MR dampers is evaluated under seismic response. It is compared under four methods, including passive-off, passive-on, and two semi-active control strategies: ANFIS and LQR. Besides, various types of feedback of the ANFIS operated as two-input single output feedback system are investigated to assess the performance of the developed control scheme for structural vibration control. The numerical simulation results show that the proposed semi-active control system consisting of coupled buildings system and MR dampers by utilizing ANFIS can be effective in mitigating seismic responses of structures.
The Lipopolysaccharide-Sensing Caspase(s)-4/11 Are Activated in Cirrhosis and Are Causally Associated With Progression to Multi-Organ Injury
Authors: Soffientini Ugo , Beaton Nigel , Baweja Sukriti , Weiss Emmanuel , Bihari Chhagan , Habtesion Abeba , Patel Vishal , Paradis Valerie , Sharma Archana , Luong Tu Vinh , Hall Andrew , Nadar Aida , Sarin Shiv , Chokshi Shilpa , Williams Roger , Py Benedicte , Moreau Richard , Jalan Rajiv , Mehta Gautam
Published: December 2022

Graphical Abstract

Model of caspase-4/11 activation in cirrhosis. Gut-derived bacterial LPS (1) enters the portal circulation after translocation across the gut epithelium and is internalized by hepatocytes. Cytoplasmic LPS is recognized by caspase-4/11 (2), which undergoes self-activation upon ligand binding. The activity of caspase-4/11 is enhanced by endoplasmic reticulum stress (3), which occurs in fibrosis/cirrhosis, leading to “sensitization” of this pathway. Active caspase-4/11 cleaves the dimeric protein Gasdermin D (GSDMD) (4), and freeing the N-terminal domain to migrate to the plasma membrane and form GSDMD N-terminal octameric pores (5). GSDMD pores insert themselves into the plasma membrane, allowing the deregulated passage of molecules and causing cell swelling and membrane rupture, eventually resulting in pyroptotic cell death (6).
Autophagy in glaucoma pathogenesis: Therapeutic potential and future perspectives
Authors: Li Min , Gao Zhao-Lin , Zhang Quan-Peng , Luo Ai-Xiang , Xu Wei-Ye , Duan Tian-Qi , Wen Xu-Peng , Zhang Ru-Qi , Zeng Ru , Huang Ju-Fang
Published: December 2022

Glaucoma is a common blinding eye disease characterized by progressive loss of retinal ganglion cells (RGCs) and their axons, progressive loss of visual field, and optic nerve atrophy. Autophagy plays a pivotal role in the pathophysiology of glaucoma and is closely related to its pathogenesis. Targeting autophagy and blocking the apoptosis of RGCs provides emerging guidance for the treatment of glaucoma. Here, we provide a systematic review of the mechanisms and targets of interventions related to autophagy in glaucoma and discuss the outlook of emerging ideas, techniques, and multidisciplinary combinations to provide a new basis for further research and the prevention of glaucomatous visual impairment.
Identification of novel immune-related targets mediating disease progression in acute pancreatitis
Authors: Liu Qiang , Li Lingyun , Xu Dongchao , Zhu Jianpeng , Huang Zhicheng , Yang Jianfeng , Cheng Sile , Gu Ye , Zheng Liyun , Zhang Xiaofeng , Shen Hongzhang
Published: December 2022

Introduction

Acute pancreatitis (AP) is an inflammatory disease with very poor outcomes. However, the order of induction and coordinated interactions of systemic inflammatory response syndrome (SIRS) and compensatory anti-inflammatory response syndrome (CARS) and the potential mechanisms in AP are still unclear.

Methods

An integrative analysis was performed based on transcripts of blood from patients with different severity levels of AP (GSE194331), as well as impaired lung (GSE151572), liver (GSE151927) and pancreas (GSE65146) samples from an AP experimental model to identify inflammatory signals and immune response-associated susceptibility genes. An AP animal model was established in wild-type (WT) mice and Tlr2-deficient mice by repeated intraperitoneal injection of cerulein. Serum lipase and amylase, pancreas impairment and neutrophil infiltration were evaluated to assess the effects of Tlr2 in vivo.

Results

The numbers of anti-inflammatory response-related cells, such as M2 macrophages (P = 3.2 × 10–3), were increased with worsening AP progression, while the numbers of pro-inflammatory response-related cells, such as neutrophils (P = 3.0 × 10–8), also increased. Then, 10 immune-related AP susceptibility genes (SOSC3, ITGAM, CAMP, FPR1, IL1R1, TLR2, S100A8/9, HK3 and MMP9) were identified. Finally, compared with WT mice, Tlr2-deficient mice exhibited not only significantly reduced serum lipase and amylase levels after cerulein induction but also alleviated pancreatic inflammation and neutrophil accumulation.

Discussion

In summary, we discovered SIRS and CARS were stimulated in parallel, not activated consecutively. In addition, among the novel susceptibility genes, TLR2might be a novel therapeutic target that mediates dysregulation of inflammatory responses during AP progression.
Spatial capture-recapture and LiDAR-derived vegetation metrics reveal high densities of ocelots on Texas ranchlands
Authors: Lombardi Jason V. , Sergeyev Maksim , Tewes Michael E. , Schofield Landon R. , Wilkins R. Neal
Published: December 2022

Reliable estimates of population density and size are crucial to wildlife conservation, particularly in the context of the Endangered Species Act. In the United States, ocelots (Leopardus pardalis pardalis) were listed as endangered in 1982, and to date, only one population density estimate has been reported in Texas. In this study, we integrated vegetation metrics derived from LiDAR and spatial capture-recapture models to discern factors of ocelot encounter rates and estimated localized population estimates on private ranchlands in coastal southern Texas. From September 2020 to May 2021, we conducted a camera trap study across 42 camera stations on the East Foundation’s El Sauz Ranch, which was positioned within a larger region of highly suitable woody and herbaceous cover for ocelots. We observed a high density of ocelots (17.6 ocelots/100 km2) and a population size of 36.3 ocelots (95% CI: 26.1–58.6) with the 206.25 km2 state space area of habitat. The encounter probability of ocelots increased with greater canopy cover at 1-2 m height and decreasing proximity to woody cover. These results suggest that the incorporation of LiDAR-derived vegetative canopy metrics allowed us to understand where ocelots are likely to be detected, which may aid in current and future population monitoring efforts. These population estimates reflect the first spatially explicit and most recent estimates in a portion of the northernmost population of ocelots in southern Texas. This study further demonstrates the importance of private working lands for the recovery of ocelots in Texas.