bluuebunny/crossref_metadata_2025 huggingface dataset:
Implementação da Ferramenta MRP: Análise de uma Empresa Siderúrgica do Sul de Minas Gerais
Authors: Tobias Cristiane De Cássia , Rodrigues Roger Antônio , Silva Sheldon William , Portugal Júnior Pedro Dos Santos , Faria Thiago De Carvalho
Published: March 2019

O avanço tecnológico vivenciado pelas empresas nas últimas décadas tem revelado a necessidade de diferenciais em seus sistemas que as ajudem a desenvolver uma produção mais eficiente, ágil e que busque a redução de custo. Este trabalho analisa a implementação do sistema MRP em uma empresa siderúrgica de esquadrias de portas e janelas. O objetivo do estudo foi pesquisar os impactos desse sistema na função produção da empresa. Tal abordagem se faz necessária devido ao crescimento da organização e consequentemente ao surgimento de problemas com a programação e o controle de materiais, mão de obra e matéria prima. Este projeto fundamenta-se em uma revisão bibliográfica e posteriormente na construção de um estudo, observando a realidade da empresa. A análise demonstrou que a implementação tem direcionado a resultados positivos em termos de produtividade e eficiência dos processos. Durante a pesquisa verificou-se que a organização ainda enfrenta problemas com a estrutura de implementação no que tange à resistência de funcionários, subutilização do sistema e pelas características do produto. O estudo demonstrou que a utilização do sistema MRP tem influenciado no ganho da empresa, principalmente com a redução de estoques, lead time de produção e cumprimento dos prazos, com impacto direto na lucratividade da empresa. Palavras-chave: Implementação. Sistema MRP. Empresa Siderúrgica. AbstractTechnological advances experienced by companies in recent decades have revealed the need for differential in their systems that help them develop a more efficient, streamlined production and look for cost reduction. This paper analyzes the implementation of the MRP system in a steel company of door frames and windows. The objective of the study was to investigate the impact of this system on the production function of the company. Such an approach is necessary due to the growth of the organization and consequently the appearance of problems with the programming and control of materials, manpower and raw materials. This project is based on a literature review and subsequently the construction of a study looking at the reality of the company. The analysis showed that the implementation has had positive results in terms of productivity and process efficiency. During the research it was found that the organization still faces problems with the implementation structure regarding the resistance of the staff, system underutilization and the product characteristics. The study showed that the use of the MRP system has influenced the company´s profit, mainly by reducing inventories, production lead time and meeting deadlines, with direct impact on the company´s profitability. Keywords: Implementation. MRP System. Steel Company.
A Importância do Planejamento Estratégico nas Organizações
Authors: Caires Alan Felipe
Published: March 2019

O objetivo deste trabalho é demonstrar a importância do Planejamento Estratégico nas Organizações, destacando a Administração Estratégica como um planejamento eficiente e eficaz em uma organização dentro do conceito de clima de ambiente organizacional. Serão mostradas as prioridades que possuem o processo de implementação do planejamento estratégico através de uma administração, que procura esclarecer seus aspectos, missão, valores e visão de mercado, com o intuito de demonstrar através de opiniões de especialistas  como deve ser tratado o planejamento estratégico, atualmente, e qual o objetivo que o planejamento estratégico influenciará no futuro da organização, com a visão crítica e analítica da posição que o mercado atuará e a performance que a empresa irá atingir por meio da desenvoltura do planejamento estratégico aplicado. Palavras-chave: Planejamento. Administração Estratégica. Estratégia Empresarial. AbstractThe aim of this paper is to demonstrate the importance of strategic planning in the organizations, highlighting the strategic management and efficient and effective planning in an organization within the concept of organizational climate environment. Priorities will be shown that has the implementation process of strategic planning by an administration that seeks to clarify aspects, mission, values and vision of the market, aiming to demonstrate through expert opinions on how it should be dealt with planning today and what the strategic goal that strategic planning will influence the future of the organization, with a critical and analytical position that the market will act and the performance that the company will achieve through the   resourcefulness of strategic planning applied. Keywords: Planning. Strategic. Business Strategy.
Organização e Psicodinâmica do Trabalho: Diagnóstico dos Riscos Psicossociais dos Trabalhadores do Setor Administrativo de uma Multinacional em São Paulo
Authors: Pettan Lúcia Rodante Corsi , Saltorato Patrícia , Tessarini Geraldo , Sigahi Tiago Fonseca Albuquerque Cavalcanti
Published: March 2019

As dimensões psíquica e social da relação entre trabalhador e organização do trabalho interferem na percepção positiva ou negativa deste acerca do seu trabalho. Nesse sentido, este estudo objetivou diagnosticar os riscos psicossociais associados à organização do trabalho no setor administrativo de uma multinacional do interior paulista. Para tanto, a pesquisa empregou o modelo teórico-conceitual da Psicodinâmica do Trabalho, cuja investigação foi conduzida a partir de quatro dimensões, que envolvem a relação sujeito-trabalho-saúde: organização prescrita do trabalho, estilos de gestão, sofrimento patogênico e danos psicossociais. A metodologia envolveu a observação participante, a aplicação de questionário baseado no Protocolo de Avaliação dos Riscos Psicossociais no Trabalho (PROART) e a condução de entrevistas individuais abordando vivências e experiências dos trabalhadores. Foram identificados os mecanismos e expressões segundo os quais os trabalhadores percebem a concepção de suas tarefas, a organização do trabalho e os estilos de gestão. Os resultados também revelaram a ocorrência de sentimentos associados ao sofrimento no trabalho e de lacunas entre o trabalho prescrito e o real, assim como o desenvolvimento de mecanismos de defesa para enfrentar e resistir a este contexto. Palavras-chave: Organização do Trabalho. Psicodinâmica do Trabalho. Sofrimento no Trabalho. Estratégias Defensivas. AbstractThe psychic and social dimensions of the relationship on between worker and work organization interfere in the worker’s  positive or negative perception about his or her work. In this sense, the aim of this study was to diagnose the psychosocial risks associated with the work organization in the administrative sector in a multinational company located in São Paulo city, Brazil.  A theoretical-conceptual framework was drawn of the Work Psychodynamics, conducting the research based on four dimensions of the relation between individual, work, and health: prescribed  work organization, management styles, pathogenic suffering, and psychosocial damages. The adopted methodological strategies was the participant’s observation, application of a questionnaire based on the Protocol for the Evaluation of Psychosocial Risks at Work (PROART) and the conduction of individual interviews on issues related to the workers’ experiences. The mechanisms and expressions through which the workers perceive the conception of their tasks, the work organization and the management styles were identified. The results also revealed the occurrence of feelings associated with suffering at work and gaps between prescribed and actual work, as well as the development of defense mechanisms to confront and resist this context. Keywords: Work Organization. Work Psychodynamics. Suffering at work. Defensive Strategies.
Metodología para la evaluación de impacto de la extensión en la educación superior
Authors: Rincón Zapata Carolina , Pérez Cadavid Adriana
Published: March 2019

Las instituciones de educación superior (IES) desempeñan un papel fundamental en el desarrollo de estrategias orientadas a la trasformación social. El objetivo de este artículo es, proponer una metodología para la evaluación de las externalidades de las IES en la sociedad como efecto de intervenciones en sus grupos de interés desde su función de extensión y proyección social. La metodología fue, en primera instancia, descriptiva-documental para la descripción, análisis e interpretación de la naturaleza actual de las evaluaciones de impacto existentes; posteriormente, a partir de las categorías que determinan la transformación social, se plantearon las variables que podrán hacer parte de un modelo econométrico de regresión que corresponda a dichas categorías y que determina un índice de impacto. Se ofrece una propuesta en cuatro momentos: 1) identificar y construir las variables e indicadores para la medición del impacto, 2) determinar las fuentes y los instrumentos de recolección de información; 3) estimar el grupo de tratamiento y el grupo de control, y 4) recopilación y análisis de la información; al final se realiza una valoración para cada variable, donde se consideran los valores obtenidos por cada indicador, que además deberán ser ponderados.
An autopsy study of hematolymphoid malignancies
Authors: Waghmare Tejaswini P. , Prabhat Daksha P. , Keshan Pooja , Vaideeswar Pradeep
Published: March 2019

Background: Hematolymphoid malignancies (HLM) are primary cancers of blood, bone marrow and lymphoid organs associated with high mortality. Clinically undetected cases, diagnosed primarily at autopsy, are common.Methods: Cases of HLMs at autopsy performed in our hospital from 1st January 2009 to 30th June 2017 were analysed. Gross and microscopic findings at autopsy along with clinical parameters were studied. Special stains and immunohistochemistry (IHC) were performed wherever possible.Results: There were 49 cases of HLMs (0.98 %) among 4971 autopsies conducted during the study period, occurring predominantly in males (70 %). Fifteen (30.61 %) were primarily diagnosed at autopsy. There were 26 lymphomas and 19 leukemias; three patients had multiple myeloma and one patient had Langherhan cell histiocytosis. Non-Hodgkin’s lymphoma was the commonest (24 patients). Nine were diffuse large B-cell lymphoma; rare sub-types included angiotrophic lymphoma, post-renal lymphoproliferative disorder and hepatosplenic gamma-delta T-cell lymphoma. Among the 19 leukemias, majority were acute (13 cases) with seven cases of myeloid and six of lymphoid types. IHC was performed in 21 cases which aided the diagnosis. The commonest symptoms were fever (43%) and dyspnoea (37%). Splenomegaly (67%), hepatomegaly (61.2%) and lymphadenopathy (57.1%) were the most common autopsy findings. Infiltrations were seen in various organs; an acute myeloid leukemia (M6) had infiltration of the atrio-ventricular node.Conclusions: One-third cases in the present study were diagnosed at autopsy without any prior clinical suspicion thereby emphasizing on the relevance of autopsy in the current practice of pathology and further studies to improve accuracy of ante-mortem diagnosis.
Topical diltiazem versus topical glyceryl trinitrate in the treatment of chronic anal fissure: a prospective comparative study
Authors: S. Venkatesh , Kulkarni Srinivas B. , S. R. Kruthi
Published: March 2019

Background: Acute anal fissure (AAF) heals spontaneously with conservative line of treatment. Chronic anal fissure (CAF) needs either traditional surgical lateral sphicterotomy or chemical sphincterotomy with topical agents. The present study aims at the effectiveness of topical diltiazem (DTZ) cream over topical glyceryl trinitrate (GTN) ointment in the treatment of chronic anal fissure.Methods: A total of 100 patients with CAF were included in this comparative prospective study conducted in Rajarajeswari Medical College and Hospital Bengaluru from July 2017 to December 2018. Eligible patients were randomly assigned to one of the two treatment groups of 50 patients each and were advised to apply 2% DTZ cream or 0.2% GTN ointment by fingertip to the anal verge twice daily for 8 weeks. The results were analysed and compared on two weekly intervals to know the effectiveness of treatment. P value of <0.05 is considered to be significant.Results: Complete healing of the fissure occurred in 80% of the patients in DTZ group against 76% in the GTN group by the end of 6 weeks (p>0.05, statistically not significant). Mild headache was experienced by 14% of the patients in the DTZ group, while 46% of the cases in the GTN group reported about the same (p<0.05 statistically significant).Conclusions: Topical 2% DTZ appeared to be well tolerated and effective preferred first-line method of chemical sphincterotomy with less side effects for chronic anal fissure.
Study of serum HDL-cholesterol levels in sepsis patients and its prognostic significance
Authors: Gaddam Bhargav Kiran , Narayanan M.
Published: March 2019

Background: Sepsis is the second leading cause of mortality in the ICU. Despite advances in aggressive management, sepsis continues to have a high mortality rate, hence a prognostic marker is essential. Recently HDL-cholesterol was found to be have significant association between mortality and its levels. Hence, this study is being conducted to assess the association between sepsis and HDL-C levels.Methods: It is a prospective study conducted in MGMCRI involving 100 sepsis patients. Among them 66 people survived, and 34 people expired. Serum HDL-cholesterol levels and variables required for SOFA score are measured at two intervals, one during admission and on day 5 of admission. The correlation between SOFA scores and HDL-C levels were assessed.Results: Among non-survivors SOFA score was found to be high and low in the survived patients. Similarly, HDL-C values, were high in survived patients and low in dead patients. The correlation between SOFA scores and HDL in both survivors and non survivors, both at the time of admission and at day 5 were found to be statistically significantly correlated.Conclusions: This study proves the significant relationship between the HDL values and the SOFA scores. Hence, HDL-cholesterol levels can be used to measure the prognosis and therapeutic efficacy in cases of sepsis. Rising values of HDL cholesterol favour improvement in clinical condition and falling values imply worsening and there by providing a prognostic indicator.
Hydrogen Embrittlement and Diffusion in High Strength Low Alloyed Steels with Different Microstructures
Authors: Cabrini Marina , Sergio Lorenzi , Diego Pesenti Bucella , Tommaso Pastore Tommaso
Published: March 2019

The paper deals with the effect of microstructure on the hydrogen diffusion in traditional ferritic-pearlitic HSLA steels and new high strength steels, with tempered martensite microstructures or banded ferritic-bainitic-martensitic microstructures. Diffusivity was correlated to the hydrogen embrittlement resistance of steels, evaluated by means of slow strain rate tests. 
Cultura virtual e subjetividade na idade mídia: contemplações críticas com Joana Peixoto
Authors: Oliveira Evandro Salvador Alves , Miranda Neto Henrique Carivaldo de , Cunha Neto Júlio Henrique , Cecílio Sálua
Published: March 2019

A temática da cultura virtual e midiática presente nas discussões instauradas na academia traz pontos e contrapontos que oportunizam críticas e debates. Por um lado, desafiam consensos capazes de cristalizar e engessar ideias e ações, por outro, distorcem imagens tão bem desenhadas na história das telecomunicações. Nessa direção, o propósito dessa entrevista é trazer à tona algumas contemplações sobre as controvertidas relações entre educação e tecnologias na sociedade neoliberal e seus efeitos na produção de subjetividades. Para tanto, debruçamo-nos sobre esse campo de conhecimento, por meio de uma entrevista realizada com a pesquisadora brasileira, Joana Peixoto (J.P.), que se destaca no cenário nacional pelos legados e inúmeras contribuições registradas na área em que atua. Considerando a larga experiência como pesquisadora e docente na área da educação, apresentamos, de modo breve, um panorama da formação da entrevistada, bem como os interesses que possui. Joana Peixoto possui produção arbitrada e divulgada em periódicos qualificados com trabalhos científicos. Por essa razão pensamos ser muito relevantes as experiências constituídas pela Professora no terreno da formação de professores, assim como as relações com as mídias eletrônicas e tecnologias digitais.
Erişkin hastalarda kardiyopulmoner bypass sonrası gelişen akut böbrek hasarının erken tanısında neutrophil gelatinase-associated lipocalin ve sistatin C’nin önemi
Authors: YILDIZ Okan , ÇAPÇI Selim , ÜNLÜ Ahmet , ŞİMŞEK Baran , PAŞAOĞLU İlhan
Published: March 2019

Amaç:
Kardiyopulmoner bypass sonrası oluşan akut böbrek hasarı (CPB-ABH) mortalite ve
morbidite artışı ile ilişkilidir. Postoperatif dönemde ABH erken tanısını
sağlayacak biyobelirteçler tedavi başarısını artırabilir. Bu çalışmanın amacı neutrophil gelatinase-associated
lipocalin (NGAL) ve sistatin C (Cys C)
seviyelerini ölçmek ve erken biyobelirteç olarak doğruluk ve güvenilirliği test
etmektir.Gereç
ve Yöntemler: Çalışmamız CPB kullanılarak uygulanan
kalp cerrahisi sonrası ABH gelişen hastalarda kreatinin, NGAL ve Cys C
düzeylerini karşılaştıran prospektif gözlemsel bir çalışmadır. Kırk üç hasta
çalışmaya dâhil edildi. CPB'nin başlatılmasından sonra, önceden belirlenmiş iki
zaman noktasında (6 ve 24 saat) NGAL ve Cys C için kan örnekleri alındı.Bulgular:
AKIN sınıflamasına göre, 8 hasta (% 44) ABH gelişti, 35 (% 56) hastada ABH
gözlenmedi. Tüm parametreler için işletim karakteristiği eğrisi altında kalan
alan (AUCROC) hesaplandı. AUCROC değeri 6.saat NGAL için
0,81 (%95 CI:0,63-1,0 p=006) ve 24. Cys C. için 0,867 (95% CI: 0,00-1,00 p:
0,004) idi. Bu nedenle, 6. saat NGAL ve 24. saat Cys C değerleri ABH teşhisi
için tanısal değere sahiptir.

Sonuç:
Çalışmamıza göre, 6. saatte NGAL ve 24. saatte Cys C düzeyleri, CPB-ABH erken
teşhisi için güçlü bir tanısal değere sahiptir.
The royal blood. Polish descendants of Sigismund I the Old and Katarzyna Telniczanka in the old Polish times
Authors: Anusik Zbigniew
Published: March 2019

The research undertaken by the Author concentrates on Polish descendants of Regina, the elder of two daughters of King Sigismund I the Old and his long time mistress – Katarzyna Telniczanka. Until now, it was assumed that the last descendants of the king were his great-grandsons – Władysław Strasz of Białaczów and his sister Krystyna who lived in the first half of the 17th century. Thanks to the documents found by the Author, it was possible to establish that the mother of the above-mentioned Władysław and Krystyna – Urszula Strasz née Kreza, had a sister – Zofia, who married Baltazar Lutomirski. From her daughter, Zofia née Lutomirski 1st married Stanisław Trembiński (Trębiński), 2nd married Franciszek Szamowski, come all descendants of Sigismund I the Old and Katarzyna Telniczanka, both historical and living ones. The article presents a list of all the king’s descendants from the beginning of the 16th to the turn of the 18th and 19th century. In total, it was 114 people (58 men and 56 women). It is worth noting that until the end of the first quarter of the 17thcentury, the descendants of Sigismund I and Katarzyna Telniczanka were Calvinists. They were almost exclusively representatives of wealthy and middle-class nobles. There were no senators among them and only a few were land officers. Yet, the Author’s list of descendants of the penultimate Jagiellon on the Polish throne is by no means complete. In a few cases it was impossible to find a source that would confirm whether a married couple mentioned in the article had children. Many times the Author had to underline that the fate of a certain person is unknown to him. This stands a chance for further researchers to fill that gap.
‘Gazeta Warszawska’ on the Russo-Turkish War (the 1789 campaign)
Authors: Karkocha Małgorzata
Published: March 2019

The article presents a selected campaign of the Russo-Turkish War, which Turkey fought with Russia and its ally, Austria, in 1787–1792. The Author used the reports of „Gazeta Warszawska” – a leading information magazine, published in 1774–1793 under the editorial supervision of an ex-Jesuit, Father Stefan Łuskina, as the principal source of information. Throughout the entire conflict, Łuskin’s newspaper reported regularly (almost in every issue) on activities on the eastern front. The editor-in-chief was an advocate of pro-Russian position, which did affect the information provided by the publication. The news from the Eastern War published in „Gazeta Warszawska” was selected in such a way as to show the superiority of the Russian army over the Ottoman fleet and army and to prove that the opponents of the Tsaritsa opponents would be inevitably defeated.
St. Anne’s prebend in Małogoszcz in the mid-nineteenth century
Authors: Karkocha Małgorzata
Published: March 2019

-
Władylena Sokyrska, Widnostiny miż RSFRR i USRR (1919–1929 rr): administratiwno-teritorialnyj ta politiko-ekonomicznyj dyskurs, Wydawień Soczynskij М.М, Umań 2017, pp. 578 + unnumbered pages 2.
Authors: Srogosz Tadeusz
Published: March 2019

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Effect of Designed Teaching Protocol Regarding Patients' Safety after Cardiac Catheterization on Nurses' Performance and Patients’ Incidence of Vascular Complications
Authors: Ali Heba Abd Elkader , Ali Marwa Mosaad
Published: March 2019

Background: Vascular access-site complications are an important cause of morbidity and mortality, which is related mainly to vascular percutaneous intervention procedures and requires safe and standardized care policies, as well as qualified and skilled health provider to obtain good outcome of management. Aim of the study: to investigate the effect of designed teaching protocol regarding patients’ safety after cardiac catheterization on nurses’ performance and patients’ incidence of vascular complications. Aquasi-experimental design was used to conduct the current study in cardiac catheterization and coronary care units at Benha University Hospital during the period from beginning of April 2018 till beginning of October 2018. Subjects: A sample of convenience of 50 nurses who are willing to participate in the study, and patients who admitted for performing cardiac catheterization were 170 patients recruited according to the study formula based on the total number admitted to the study settings during 2017. Tools: Two tools were utilized for data collection, (Ι) Structured interviewing questionnaire for nurses, (II) Patients’ assessment sheet. Results: Showed that nurses’ level of knowledge and practice post implementing the designed teaching protocol was higher than pre implementation, with a significant correlation between nurses’ knowledge and practice(p= <0.001**), besides a lower incidence of complications among patients in intervention group than in control group . Conclusion: The designed teaching protocol was effective in improving nurses’ knowledge and practice, which were positively associated with each other and lower incidence of vascular complications among patients in the intervention group. Recommendation: The study suggested equipping cardiac catheterization unit with simple illustrated guidelines protocol covering percutaneous coronary intervention procedure practices knowledge pre/post cardiac catheterization.
Pengaruh Jarak Tanam dan Pemberian Dosis Pupuk Kandang Sapi Terhadap Peertumbuhan Bawang Merah (Allium ascalonicum.L)
Authors: JUWANDA MUHAMMAD
Published: March 2019

Penelitian ini bertujuan untuk upaya peningkatan produksi dan hasil budidaya tanaman bawang merah yang berwawasan lingkungan dengan pemanfaatan pupuk kandang sapi dan pengaturan jarak tanam.Penelitian dilaksanakan selama 8 bulan daribulan Januari sampai dengan Agustus 2015.Penelitian dilakukan di lahan sawah Brebes, Kabupaten Brebes, jenis tanah alluvial dengan ketinggian tempat kurang lebih 50 m dpl. Penelitian ini merupakan percobaan faktorial 4 x 3 dengan rancangan lingkungan adalah rancangan acak kelompok. Faktor pertama adalah Jarak Tanam : J1 =   20 cm x 20 cm, J2 =   20 cm x 15 cm, J3 =   20 cm x 10 cm. Faktor yang kedua adalah takaran pupuk kandang sapi yaitu K0  =  0ton/ha, K1  = 10 ton/ha, K2 = 20 ton/ha, K3 = 30 ton/ha. Data hasil pengamatan dianalisis dengan uji F untuk mengetahui keragamannya dan apabila ada perbedaan nyata dilanjutkan dengan DMRT dengan tingkat kesalahan 5%. Hasil penelitian menunjukkan bahwa hasil umbi segar dan kering bawang merah per hektar terbanyak diperoleh pada tanaman dengan perlakuan jarak tanam 20 x 15 cm dengan hasil 20,56 t/ha (umbi segar) dan 18,63 t/ha (umbi kering).Kata kunci : bawang merah, jarak tanam, pupuk kandang[U1]  sapi  [U1]pupuk kandang sapi
KARAKTER PERTUMBUHAN KACANG TANAH (Arachis hypogaea L.) DENGAN PEMANFAATAN KOMPOS LIMBAH BAGLOG JAMUR DAN KOTORAN DOMBA
Authors: Sobari Enceng , Fathurohman Ferdi , Hadi Muhammad Abdul
Published: March 2019

Penelitian ini bertujuan untuk mengetahui pengaruh pemberian kompos limbah baglog dan pupukkandang domba terhadap karakter pertumbuhan. Penelitian dilaksanakan pada bulan April sampai Juni 2018 diJalan Cagak Desa Tambakan, Kabupaten Subang, Jawa Barat. Penelitian menggunakan (RAK) faktorial dengantiga kali ulangan. Terdapat 2 faktor yang diteliti yaitu kompos limbah baglog jamur dan pupuk kandang domba.Dosis kompos limbah baglog jamur (K) terdiri dari: K0 = tanpa kompos baglog, K1 = kompos baglog 90 gtanaman-1, K0 = kompos baglog 120 g tanaman-1. Pupuk kandang domba (P) terdiri dari: P0 = tanpa pupukdomba, P1 = pupuk domba 90 g tanaman-1, P2 = pupuk domba 120 g tanaman-1. Pengamatan dilakukan terhadapkarakter pertumbuhan tanaman meliputi tinggi tanaman, jumlah daun, indeks luas daun dan bobot keringberangkasan tanaman. Hasil penelitian dosis kompos limbah baglog memberikan respon terbaik pada semuakarakter pertumbuhan dan t bobot kering berangkasan tanaman pada umur 5 MST, 10 MST. Perlakuan pupukkandang domba memberikan pengaruh paling baik pada umur 14 MST.Kata kunci: Arachis hypogaea L., baglog jamur, kacang tanah, karakter pertumbuhan, pupuk kandang dombaABSTRACTThe aim of this research is to know the effect of the compost made of baglog waste and lamb manure ongrowth character. This research was carried out in April to June 2018 in the Cagak Road Tambakan Village ofSubang on West Java. The study used a factorial (Randomized Group Design) with three times repeats. Thereare two factors that are baglog waste compost and lamb manure. Dose of compost baglog waste compost are ;K0 = without baglog waste compost, K1 = 90 g plant-1 baglog waste compost, K0 = 120 g plant-1 baglog wastecompost. Dose of lamb manure are; P0 = without lamb manure, P1 = 90 g plant-1 lamb manure, P2 = 120 gplant-1 lamb manure. Observations were made to the plant's vegetative characters i.e. plant height, number ofleaves, Leave Area Index and the dry weight of plant. The results of research on baglog waste compost dosesgave the best response to all growth characters and t-crop dry weight at age 5 MST, 10 MST. The treatment ofsheep manure had the best influence at the age of 14 MST.Key words: Arachis hypogaea L., mushroom baglog waste compost, peanut, growth character, manure of lamb
Glycosaminoglycan Derived from Field Cricket and Its Inhibition Activity of Diabetes Based on Anti-Oxidative Action
Authors: Ahn Mi Young , Kim Ban Ji , Kim Ha Jeong , Jin Jang Mi , Yoon Hyung Joo , Hwang Jae Sam , Lee Byung Moo
Published: March 2019

Field cricket (Gryllus bimaculatus) is newly emerged as an edible insect in several countries. Anti-inflammatory effect of glycosaminoglycan derived this cricket was not fully investigated on chronic disease animal model such as diabetic mouse. For potential therapeutic agents, anti-diabetic activities of field cricket glycosaminoglycan (GbG) was evaluated in diabetic mice based on their abilities to reduce glucose, ALT, AST, LDL-cholesterol, and BUN levels, compared with  dung beetle (Catharsius molossus) glycosaminoglycan (CaG) as a positive control glycosaminoglycan.  Db mice were orally administered for one month according to their groups: Db Hetero (normal), Db Homo (type-2 diabetic), CaG (5 mg/kg), GbG (5 mg/kg), and metformin (10 mg/kg). Blood glucose level was decreased after 1st week treatment with GbG. It also inhibited LDL-cholesterol and alkaline phosphatase levels. Regarding oxidative damage of diabetic state, levels of hepatocellular biomarkers levels and protein carbonyl content were reduced in db mice treated with GbG. Especially anti-oxidative activities of catalase, superoxide dismutase, and glutathione peroxidase were significantly increased in GbG treated group compared to those in the control. GbG was composed of heparin disaccharides and main N-glycan was identified as Hex9GlcNAc2 (m/z 1905.7) of with neutral mono-sugar mainly comprising of hexose, L (+) rhamnose by mass spectroscopy. These results from sero-biochemical, hepatocellular anti-oxidant assay in db mice data suggest cricket (G. bimaculatus) glycosaminoglycan might play a role in its anti-diabetic action.
Genetic Characterization of Thyroglobulin and Leptin Genes in Pasundan Cattle at West Java
Authors: Putra Widya Pintaka Bayu , Anwar Saiful , Said Syahruddin , Indarto Romanos Albert Adhitya , Wulandari Putri
Published: March 2019

The Thyroglobulin (TG) and Leptin (LEP) genes are two candidate genes that widely used for molecular selection to improve carcass traits in beef cattle. This research was carried out to identify the genetic characterization of TG and LEP genes from 47 heads of Pasundan cows at West Java using PCR-RFLP method. Research shows that TG gene of Pasundan cattle is monomorphic with C allele as the dominant allele (1.00). However, LEP gene of Pasundan cattle is polymorphic with C allele as the dominant allele (0.98) and T as the rare allele (0.02). The polymorphic informative content (PIC) and numberof effective allele (ne) values in the LEP gene in the animal studied were 0.04 and 1.04 respectively. It was concluded that TG/BstYI and LEP/Sau3AI gene in the present study can not be used as molecular selection in Pasundan cattle. These results are important as the basic information for preparing the molecular selection program in the future.
The Effect of Storage Time on the Total Lactic Acid Bacteria and Presence of Gram Positive and Negative Bacteria in Calf Starter Pellet Added with Fermented Cabbage Waste
Authors: Mukodiningsih Sri , Pujaningsih Retno Iswarin , Resniati Resniati , Astuti Andriyani
Published: March 2019

The aim of this research was to examine the microbiological quality of calf starter pellet added with fermented cabbage waste after stored for 0, 4, and 6 weeks. The materials used in this research consisted of cornmeal, rice bran, soybean meal, molasses, mineral mix, and fermented cabbage waste. This research used Completely Randomized Design with 4 treatments and 3 replications. The mixed calf starter pellet consisted of 100% calf starter and 6% of fermented cabbage waste, and then stored for 0 weeks (P0), 2 weeks (P1), 4 weeks (P2) and 6 weeks (P3). The observed microbial qualities were the total lactic acid bacteria and the presence of gram positive and negative bacteria in the mixed calf starters. The total lactic acid bacteria were analyzed descriptively, while the presence of gram bacteria was analyzed with analysis of variance followed with Duncan’s test. The result of this research showed that an increase in storage time would result in lower lactic acid bacteria population, while the gram-positive and negative bacteria was not significantly affected. The research concluded that 6-weeks stored calf starter pellet added with 6% of fermented cabbage waste could maintain its lactic acid and gram-positive bacteria population, while also reducing its gram-negative bacteria population as well.
Prevalence of Salmonella Spp. Bacteria Antibiotic Resistency Indigestion Tract in the Broiler Farms of Subang District
Authors: Walyani Septa , Purnawarman Trioso , Sudarnika Etih
Published: March 2019

This study is aimed to  estimate the prevalence of resistant Salmonella spp., determine the spread of bacterial resistance and investigate the serotypes of bacteria in the chicken’s digestion tract in the broiler farms in Subang District. As many as 74 farms were chosen, five poled caeca samples were taken from each farm and tested for isolation and identification of Salmonella spp. Salmonella isolates obtained were tested antimicrobial susceptibility against 8 antibiotics using the agar dilution method. The antibiotics were gentamycin, tetracycline, ciprofloxacin, nalidixic acid, ampicillin, chloramphenicol, trimethoprim, and sulfamethoxazole. The result showed that 8 out of 74 samples were positive for Salmonella. The prevalence of Salmonella spp. in the digestion tract was 10.8%; 95% confidence interval 3.7%-17.9%. Based on the serological test eight serotypes obtained were Salmonella enteritidis, Salmonella oslo, Salmonella narashino, Salmonella nakuru, and Salmonella nordufer. The result of antibiotic resistance test showed that from 8 Salmonella isolates obtained, 12.5% were found to be sensitive, 75% isolates were resistant to one or two antibiotics, and the remaining 12.5% isolates were resistant to more than two antibiotics; 95% confidence interval (0%-35.4%). The prevalence of resistant Salmonella spp. bacteria in chicken digestion tract in broiler farms in Subang District was high, so integrated control program to reduce antimicrobial resistance problem in broiler farm are greatly needed.
CBHP MPD Assisted Casing Drilling: A Novel MPD Solution Combining Two Drilling Technologies, Planned and Executed on Otherwise Not Drillable Multiple Directional Wells in North America
Authors: Nauduri Sagar , Parker Martyn , Nabiyev Akram , Sampley Eddy , Kirstein Lenord , Morris Jason , Wilkinson Matthew , Buckner Jason
Published: March 2019

A novel drilling solution, ‘Constant Bottomhole Pressure (CBHP) Managed Pressure Drilling (MPD) assisted Casing Drilling operation', was designed, planned and successfully executed for different operators on multiple directional wells in North America. These wells were otherwise not drillable either conventionally or with CBHP MPD using conventional drillpipe-BHA; and over the last few decades several operators tried and failed to reach the Target Depth (TD) on multiple occasions when drilling some of these formations.

One operator drilled in formations prone to severe faulting/fracturing and with very high permeability, while a different operator drilled through multiple weak zones interbedded with over-pressured and highly conductive regions. Both scenarios resulted in similar issues with fluid displacement, tripping/surge and swab, kicks and losses, running casing and cementing. The generic CBHP MPD solution with a conventional drillpipe-BHA even with ‘Anchor Point' CBHP MPD and its variations was not successful in either of these scenarios in drilling to the TD.

As demonstrated using case histories, the success in these projects was a result of combining two technologies – ‘CBHP MPD' and ‘Casing Drilling'. Pre-planning, understanding formation constraints, training, and having knowledgeable and experienced people involved, enabled safe and successful execution of CBHP MPD assisted Casing Drilling on these projects and helped CBHP MPD develop and reach new horizons.
Nitrogen Cap Drilling A Managed Pressure Drilling Alternative for Highly Fractured Carbonate Reservoir
Authors: Podust Alexey , Starkey Craig , Wood Jeff , Cameron Gareth
Published: March 2019

Nitrogen Cap Drilling (NCD) is a technique developed by Tengizchevroil (TCO) that enables drilling a highly fractured reservoir under conditions where more conventional pressurized mud cap drilling techniques are not viable. NCD is an extension of the closed hole circulating drilling (CHCD) technique (Ref SPE Paper # 79850) previously developed and used extensively by TCO for drilling a highly fractured carbonate reservoir where severe loss circulation is encountered and incurable.

CHCD is a pressurized mud cap drilling technique that relies on the ability to fill the well with a fluid density lighter than the reservoir pressure gradient in order to maintain communication with the reservoir pressure. Once the reservoir pressure gradient drops below the density of the lightest fluid available, the well will no longer support a full column of fluid to surface and an alternate drilling method must be employed.

TCO has developed NCD as a response to this operating reality in the Tengiz field. The NCD technique involves filling the annulus with a heavier than reservoir pressure gradient fluid once severe lost returns are encountered. The annulus fluid level does not reach the surface, and the resulting air gap is pressurized with nitrogen gas. This nitrogen "cap" is contained under the Rotating Control Device (RCD) which allows for maintaining pressure communication with the formation. Well status is continuously monitored by tracking the wellhead pressure and measuring the annulus fluid level. The bottom hole pressure is balanced by manipulating the composition of the annular fluid column and controlling the wellhead pressure.

In 2017, TCO conducted successful field trials and demonstrated that NCD is a viable technique to enable the continuation of the low reservoir pressure drilling program in Tengiz. TCO has since adopted NCD as the standard technique in wells where CHCD is not technically viable or operationally preferable. This paper will describe NCD technique development, equipment, procedures, operational implementation, and key learnings to date.
Influx Management Envelope: Limits Redefinition and Parametric Sensitivity Analysis Based on Data and Lessons Learned from Offshore Applications
Authors: Gabaldon Oscar , Gonzalez Romar A , Bacon William , Brand Patrick
Published: March 2019

The Influx Management Envelope (IME) assists in identifying influx conditions which could compromise the primary well barrier and fluid handling capacity on surface. IME boundaries are influenced by changes in parameters such as mud weight, wellbore depth and geometry, pump rate, surface pressure, etc. Thus, any changes to these parameters will change the acceptable influx volume and intensity for Dynamic Influx Management. It is, therefore, critical to understand how changes in each of these variables affect IME limits so that its validity can be established within parameter ranges, rather than only for discrete values.

This work presents an in-depth discussion of how IME limits are determined, with both detailed philosophical and practical guidance on methods to calculate the surface and subsurface limits. Recent deepwater applications of the IME are used to represent baselines for presenting methods of calculating IME limits, including a basic single bubble approach, through to the most robust approach of including transient, multiphase simulations. Parameter sensitivity analyses are performed to determine reasonable ranges for which an IME is valid, with the goal of understanding the required IME update frequency during operation.
Utilization of Managed Pressure Drilling in Deep High Pressure High Temperature Gas Wells
Authors: Moid Farrukh , Ghamdi Ahmed A. , Nutaifi AbdulRahman M. , Utaibi Abdullah A.
Published: March 2019

Drilling in high pressure high temperature (HPHT) deep gas reservoirs, with multiple shallow different pressure horizons, requires special techniques which include application of Managed Pressure Drilling (MPD), revising casing setting depths, improving casing strength, and refining mud design. This paper focuses on application of MPD in HPHT gas wells and also describes briefly other techniques which can improve drilling performance and reduce non-productive time.
Road to Success in MPD - Vaca Muerta Case History
Authors: Bulant Ezequiel , Gabaldon Oscar , Bedoya Jorge
Published: March 2019

Challenging drilling operations in the Vaca Muerta unconventional shale gas play have prompted operators to implement innovative drilling techniques to improve drillability and operational efficiency. Significant benefits have been reported by utilizing Managed Pressure Drilling (MPD), Underbalanced Drilling (UBD), and/or drilling with casing; however, challenges still exist, due to a variety of reasons. The heterogeneity found from field to field and within fields has resulted in wells with significant events, some resulting in loss of the well, even on the same pad where a previous well has been drilled uneventfully.

Arguably, the most successful non-conventional drilling technique being incrementally used in the area is MPD, often combined with UBD, particularly in gas wells. As with any new technology implementation, there is a learning curve which can be accelerated by translating learnings from successful experiences.

Three key components for a successful implementation on MPD are still building a collective experience in the Vaca Muerta play. Firstly, the equipment and associated technology is the key enabler for physically perform the operations safely and efficiently.

The second component is a ‘soft’ framework consisting of a robust layered approach including overarching standard policies, the MPD strategy for implementation in the specific project, conceptual and detailed procedures, and specific work instructions.

Lastly, the human component is a group of competent personnel, whom, at their specific responsibility level, understand the ‘soft’ framework, and knows how to operate the hardware to implement the technology so that objectives are met.

The potential of the technology is limited to the weakest of these three components. A strong combination of any two of them, not complemented by the third one, will most likely result in a partial success at best, if not a complete failure at worst.

The operator had recently three major events in wells being drilled with MPD, which resulted in the loss of the wells. After implementing a training program on MPD/UBD, which emphasized the human factor and understanding of the equipment, the ‘soft’ framework of strategy, procedures and project management, the safety and efficiency during operations has increased significantly. This resulted in a better handling of events related to bottom hole pressure control without a single well loss event to the date of writing this document, approximately nine months of continuous operations. The other mainstay of this process has been the flexibility to adapt the application of the methodology based on the well challenges encountered.
Applying complexity theory to model the operation of clinical trials in human communities
Authors: Berg Machteld van den , Ogutu Bernhards , Sewankambo Nelson K , Merten Sonja , Biller-Andorno Nikola , Tanner Marcel
Published: March 2019

Background

When a vaccine clinical trial enters a human community two independent systems merge into one system with various levels if interdependence. This system exhibits non-linearity and unpredictability, creating challenges for the research team. In this study we explore the researcher experience during clinical trials in human communities, through the lens of complexity theory.

Methods

We conducted in-depth interviews with a total of 11 researchers working on a phase III vaccine clinical trial in Kenya (Registry name: RTS,S ClinicalTrials.gov; Registry number: NCT00866619; Registry date: March 20, 2009). The interviews captured the researcher’s experience of working in a complex adaptive system and were analysed using thematic coding.

Results

Both human communities and clinical trials have the attributes characteristic of complex adaptive systems. Challenges researchers encountered working in this merged system include rumours, suspicion related to blood draws, and misconceptions. The researchers highlighted that a foundation of trust and open communication were foundational blocks to embrace the non-linearity of the system.

Conclusions

We have identified the key role that complexity theory plays in improving clinical trial design. The factors identified by our respondents, as seen through the lens of complexity theory, are integral to informing how clinical trial research can be tailored to the local social setting. Understanding the system (community and trial) as one allowed for the identification of patterns that influence the emergence of the system. This calls for clinical trial design to incorporate iterative practices to better equip research teams to adapt to the emerging behaviour of the system.
Outcome prediction in disorders of consciousness: the role of coma recovery scale revised
Authors: Lucca Lucia Francesca , Lofaro Danilo , Pignolo Loris , Leto Elio , Ursino Maria , Cortese Maria Daniela , Conforti Domenico , Tonin Paolo , cerasa antonio
Published: March 2019

Background: To evaluate the utility of the revised coma remission scale (CRS-r), together with other clinical variables, in predicting emergence from disorders of consciousness (DoC) during intensive rehabilitation care.
Method: Data were retrospectively extracted from the medical records of patients enrolled in a specialized intensive rehabilitation unit. 123 patients in a vegetative state (VS) and 57 in a minimally conscious state (MCS) were included and followed for a period of 8 weeks. Demographical and clinical factors were used as outcome measures. Univariate and multivariate Cox regression models were employed for examining potential predictors for clinical outcome along the time.
Results: VS and MCS groups were matched for demographical and clinical variables (i.e., age, aetiology, tracheostomy and route of feeding). Within 2 months after admission in intensive neurorehabilitation unit, 3.9% were dead, 35.5% had a full recovery of consciousness and 66.7% remained in VS or MCS. Multivariate analysis demonstrated that the best predictor of functional improvement was the CRS-r scores. In particular, patients with values greater than 12 at admission were those with a favourable likelihood of emergence from DoC.
Conclusions: Our study highlights the role of the CRS-r scores for predicting a short-term favorable outcome.
The internet and e-commerce diffusion in European countries (modeling at the example of Austria, Poland and Ukraine)
Authors: Zatonatska Tetiana , Dluhopolskyi Oleksandr , Chyrak Iryna , Kotys Nataliya
Published: March 2019

This article analyzes the influence of Internet and e-commerce diffusion in the development of European countries. Conclusions about the faster spread of Internet technologies in the modern world, especially in developing countries, due to the achievement of so-called “saturation points” by developed countries of the world (e-commerce markets in Ukraine and Poland are at the stage of formation and active growth) have been made. The purpose of this article is to construct an economic and mathematical toolkit for investigating the impact of the Internet and e-commerce on indicators of economic development of the country. The methods of scientific analysis, description and synthesis, modeling and statistical analysis are used in the research. Models of technologies diffusion have been considered, and as a basis, the distribution of the Internet in Poland, Austria and Ukraine is forecasted. Findings suggest that Internet technology spread has a significant impact on the development of e-commerce, and Internet development in different countries of the world. This study uses the classification of countries according to the World Bank Country Classification, which, since 2005, has ranked countries by GDP per capita into four groups:1) low-income;2) lower-middle-income;3) upper-middle-income;4) high-income.It has been found that the pace of Internet technology and broadband Internet access spread is a lot higher in low-income countries due to the later beginning of the diffusion process, while in the high-income countries, the peak of Internet development has passed and the technology spread has slowed down.