bluuebunny/crossref_metadata_2025 huggingface dataset:
Biden Administration Africa Policy: the first results
Authors: Parkhomenko Valentin
Published: November 2023

The article analyzes the program settings and the implementation of the Biden administration's foreign policy course with regard to Sub-Saharan African states in the political, military, and economic fields. (2021-2023).The author also considers the main directions of this policy, the State Department's assessments of the overall situation and the development of the last events on the African continent.
Gender stereotype as a Linguistic Factor of society system Arrangement
Authors:   Saratov State University, Moisova O.B.
Published: November 2023

The article is devoted to the problem which lies at the basis of the linguistic and semantic continuum factor - social gender stereotype and its influence on speech-and-thought activities and gender-role identification of men and women.
Specific Features of French speech Regionalization in France. Part I
Authors:   Saratov State University, Klokov V.T.
Published: November 2023

The article discusses theoretical and research problems of the national language differentiation illustrated by regional variants of French in France.
Belâğat Açısından Karşılaştırmalı Okuma Denemesi: Bakara Sûresinde Rızık Kelimesinin Kullanıldığı Âyetler Örneği
Authors: BAYER İsmail , HACIMÜFTÜOĞLU Esra
Published: November 2023

Din, çevre, gelenek, ihtiyaç ve karakter insanın beslenme alışkanlıklarının çerçevesini belirler. Bu bağlamda Kur’an beslenme konusuna özel bir önem hasreder. İlgili alanın öne çıkan kelimelerinden biri rızıktır. Rızık, Allah'ın canlılara faydalanmaları için verdiği şeylerdir. Geniş anlamıyla çocuklar, eş, eylem, bilgi, hikmet bu kapsamda değerlendirilebilir. Bu çalışmada, içinde rızık kelimesi geçen Bakara suresi ayetleri dil-belagat bakış açısıyla incelenerek konunun ayrıntılı verilerine ulaşılmak hedeflenmiştir. Her dilde bulunan ancak Arap dilinin karakteristiği gereği daha da özel hâle gelen cümleleri oluşturan kelimeler, kelimelerin formları, cümlenin dizgisi, ifade yolları ve üslup anlamın belirlenmesinde önemlidir. Çalışmada esas alınan belagat nüktelerinin tespitinde öncelikle karşılaştırma yöntemi uygulanmaya çalışılmıştır. Bu yöntemde ayetler, cümle ve kelimeler, bağlantılı diğer ayet ve muhtemel/kurgusal cümlelerle farklı dilsel boyutlarda karşılaştırılarak aralarındaki farklar belirlenmiş; daha sonra çıkarılan sonuçlar ilgili metin üzerinde uygulanarak sağlaması test edilmiştir. Kur’an üslûbunda yer alan her dil yapısına dikkat etmek ve anlam görevini araştırmak Kur’an’ı anlamak için elzemdir. Bu tarz okumada dil unsurlarının varlığı kadar, yokluğu da dikkate alınmalı ve anlamın belirlenmesinde etkin olarak kullanılmalıdır. Kur’an’da geçen kelimeler sadece zikredilmemekte; varlığı-yokluğu, birlikte kullanıldığı kelimelerin yapısı ve metnin bütünü, verilmek istenen mesajın önemli ve farklı bir yönünü oluşturmaktadır. Bu makalede belirtilen yöntem çerçevesinde Bakara suresinde içinde rızık kelimesinin geçtiği on ayet incelenmiştir. Uygulama şekilleri, belirtilen yöntemin anlaşılması için belli oranda örnekler sunmaktadır. Rızık kavramıyla ilgili genel toplum hayatına yansıyan yönüyle çeşitli veriler elde edilmiştir. Gıdalarda aranan temel özellikler sağlıklı, lezzetli ve hem bizatihi hem de edinim yolu olarak helâl olmalarıdır. İnsan bünyesinin gıdalardan hoşlanması çeşitli etkenlere göre farklılık gösterebilir. Ancak gıdayla ilgili getirilen yasaklamalar, makul, bilimsel veya itikadi gerekçelere dayanır. Konunun ahlaki ve felsefi boyutları, söz konusu gerekçelerin arka planında daima mevcuttur. İnsana tevdi edilen görevlerden biri de, dünyada kendisine tanınan imkân ve kabiliyetler çerçevesinde rızkı elde etme ve varsa sorumlu oldukları kişilere, canlılara ve diğer ihtiyaç sahiplerine dağıtmasıdır. Rızkın varlık sebebini dikkate alarak faydalanmak, edinim yolunun yasal ve ahlâkî olmasını gözetmek imanın gereğidir. Meşru yoldan edinim, edindiklerini paylaşım ve dağıtım işi, öncelikle vicdan duygusuyla ilişkilidir. Bundan dolayı hayvanlara, bitkilere, diğer insanlara rızık olarak verilen şeylere tasallut etmek imanın doğasında bulunmamaktadır. Bu açıdan infak, rızk kavramının anlaşılmasında önemli bir rol oynamaktadır. Kur’an insanın rızkın dağıtımında âdil ve cömert bir tutum sergilemesi isteğini güçlü bir şekilde belirtmektedir.
''Wirtualizacja'' urzędów samorządowych w Polsce
Authors: Stachowiak Zbigniew
Published: November 2023

The purpose of this article is to find out if a local government in Poland can work virtually. The author of this article made a review of a local government structure and tasks and e-government projects in Poland. He also made some remarks about Business Continuity Plans in it.
U progu przełomu politycznego w obradach Sejmu Wielkiego w początkach drugiej połowy roku 1790
Authors: Szczygielski Wojciech
Published: November 2023

In 1790 there was a political breakthrough in the debates of the Great Seym. It was marked by: a crisis of social trust in the Potocki family, the gentry’s support for the king, taking over the initiative to draft the constitution by Stanisław August. From the very beginning of 1790 the Potocki family were more and more often accused of oligarchic tendencies and an attempt to seize the control of the country for their own benefit. On the other hand, joining the Polish-Prussian alliance by Stanisław August (March 1790) made the king more and more popular both in the Seym and in the provinces. The king, having definitely rejected the pro-Russian orientation, started to be perceived by the landed gentry as a much more reliable advocate for the democracy of the gentry than the Puławy party. A special role in the breakthrough mentioned above and in taking over the con- stitutional initiative by the king was played by the elite of the gentry who wanted to shape the Commonwealth following the model of the leading free states of the contemporary world.
The article looks at the parliamentary sessions that were held in August 1790. It is during these sessions that for the first time the gentry presented, as strongly as never before, their critical attitude towards the Potocki family showing at the same time their support for the king. The August parliamentary sessions became the announcement of the political breakthrough in the seym debates which was about to happen. This breakthrough came in the first half of September 1790 when Stanisław August received the right of nomination for the highest offices, contrary to the initial intention of Ignacy Potocki (session from 13th September 1790).
The Relationship among Caring Climate, Burnout and Exercise Passion of University Taekwondo athletes
Authors:   The World Society of Taekwondo Culture, Kim Su Yeon , Choi Yeon Ho
Published: November 2023

The purpose of this study was to investigate causal relationship among caring climate, burnout and exercise passion of university Taekwondo athletes. For this purpose, a sample of 300 drawn out of the university Taekwondo athletes from NAVER platform. Data acquired from 24 university Taekwondo athletes were excluded due to inconsistency in their responses. Therefore, the data of 276 people was used for a final analysis. For the collected data, descriptive statistics, confirmatory factor analysis, correlation analysis, and structural equation analysis were performed using jamovi 1.1 and AMOS 23.0 programs. The following results. First, the caring climate has a negative(-) effect on burnout. second, the caring climate has a positive(+) effect on harmonious passion. Third, the caring climate has a positive(+) effect on obsessive passion. Fourth, the burnout has a no effect on harmonious passion. Fifth, the caring climate has a positive(+) effect on obsessive passion.
The students mathematics motivation scale: a measure of intrinsic, extrinsic, and perceptions of mathematics
Authors: Nurkarim Arfi Wahyu , Qonita Wilda , Monterroza David
Published: November 2023

Students' mathematical motivation is an important factor in understanding mathematics. Many studies have shown that students who have high motivation to learn mathematics, get better achievement than students who have low motivation. However, research that provides instruments to measure the mathematics motivation scale is still rare. This research aims to: (1) Describe the process of developing the Student Mathematics Motivation Scale (SMMS) instrument, (2) Describe the results of developing the Student Mathematics Motivation Scale (SMMS) instrument. This research model uses survey research with mixed methods. The research subjects were Junior High School students in MTs. 2 Nurul Islam, Mojokerto, Indonesia. This research produced 19 questions containing 3 main indicators, they are intrinsic goals, extrinsic goals, and perceptions of mathematics. The validity test results show a very good level of validity, as well as a high category of reliability (α = 0.817). Therefore, this instrument is very good for measuring students’ mathematics motivation scale.
Evaluation and Physical Stability Effervescent Powder of Okra Leaves Extract (Abelmoschus esculentus) as an Antidiabetic Supplement
Authors: Aditama Agnis Pondineka Ria , Ramadhani Alfi Nur , Falahi Asa , Rashati Dewi
Published: November 2023

Diabetes Mellitus (DM) is a disease characterized by hyperglycemia, and the most frequently encountered is type 2, which requires oral anti-diabetic therapy. Economic and socio-cultural factors also influence people in choosing alternative medicine. Okra (Abelmoschus esculentus (L.) Moench) is a medicinal plant containing the active substances flavonoids, α-cellulose, and hemicellulose in its leaves which have anti-diabetic properties, especially type 2 DM. This research aims to make a formula and determine the physical stability of the anti-diabetic supplement preparations in the form of effervescent powder from okra leaves extract. The method used is to make okra leaves extract effervescent powder in 3 formulations with a combination percentage of acid (tartaric and citric acid) and base (sodium bicarbonate) F1 = 27.87%: 26.8%, F2 = 26.05%: 28, 62%, F3 = 24.22%: 30.45%. The preparation evaluation includes organoleptic tests, flow rate, water content, effervescence time, pH, and hedonics for 1 and 14 days of storage at cool temperatures (8-15°C), room temperature (15-30°C), and warm temperature (30-40°C). The results showed that variations in acid-base concentration affected organoleptic, physical properties (taste), flow rate, water content, effervescence time, and pH. F3 shows the best formula and is the formula that respondents like most based on texture, color, flavor, and taste parameters. A cool temperature (8-15°C) shows the best stability because of its physical stability.
Network Pharmacology Analysis of Cananga odorata as a Treatment for Anxiety Disorders
Authors: Maretha Tri Luthfiana , Jamil Ahmad Shobrun , Rofida Siti , Muchlisin M Artabah
Published: November 2023

Anxiety disorder is a psychological disorder associated with the existence of mental disorders and experiencing constant anxiety. In C. odorata, part of the flower has the potential as a sedative for the nervous system and for dealing with anxiety. The study aims to analyze the potential compound content in Cananga odorata for treating anxiety disorders with In silico-based pharmacological network analysis. CO compound data from the KNApSAck database, Absorption, Distribution, Metabolism, and Excretion (ADME) screening using SwissADME, predicted target proteins using Swiss Target Prediction, GeneCards, Venny, String DB pharmacological network analysis, Visualization with Cytoscape version 3.10.0, and Way2drug. The results of the pharmacological tissue analysis of the compound content in C. odorata obtained 45 compounds, and 18 known active components meet the criteria of Absorption, Distribution, Metabolism, and Excretion (ADME) that correspond to the drug compounder (Drug Likeness/DL). Based on the pathway that correlates with anxiety disorder therapy are the neurotransmitter systems like serotonin receptors and dopamine receptors. The known therapeutic target proteins are HTR1A, HTR2A, SLC6A4, NR3C1, MAOA, DRD4, HSP90AA1, JUN, ten active compounds associated with C. odorata namely Anonaine, (+)-Reticuline, linalool, (-)-Coreximine, Micheline A, (-)-Ushinsunine beta-N-oxide, 4-Terpineol, alpha-Terpeneol, Sampangine, Anaxagoreine. Based on the results of research, C. odorata is potentially a treatment for anxiety disorder.
The Therapeutic Role of Olea europaea in Alcohol Dependence Base in Network Pharmacology Analysis
Authors: Awwaluddin Faiznanda , Jamil Ahmad Shobrun , Rofida Siti , Muchlisin M Artabah
Published: November 2023

Alcohol dependence is a state of alcohol becoming a vital part of the life of a person who consumes it; when discontinued, it can lead to a wide range of physical and mental health disorders as well as a decrease in life productivity in people with alcohol dependence. Olea Europaea (OE) is a plant capable of treating alcohol dependence. The method used in silico-based pharmacological grid analysis to determine the ability of the OE compound to treat alcohol dependence. EO compound data is obtained from the KnapSack database, absorption, distribution, metabolism, and excretion (ADME) screening using SwissADME, target protein prediction using SwissTargetPrediction, Gene cards, venny, pharmacological grid analysis with String-DB, visualization with Cytoscape 3.10.0. Results are obtained from 63 OE compounds, and 17 have ADME criteria matching the drug compounder (Drug Likeness/DL). The pathways that correlate with therapy are dopamine receptors, dopamine transporter, serotonin receptor, gamma-aminobutyric acid receptor, and toll-like receptors for known therapeutic target proteins: OPRM1, DRD2, ALDH2, ADH1B, ADH1A, ADH1C, ADH4, ADH7, SLC6A3, CNR1, POMC, ARRB2, and NCS1. Compounds associated with alcohol dependency therapy include Hexanal, Nonadienal, Octanal, 3-Hexenal, 3-Methyl-butanal, Methyl nominate, Cinchonidine, cinchonine, (9S)-10,11-Dihydrocinchonan-9-ol, Oleuropeic acid, Butyl acetate, cis-3-hexenyl acetate, and (S)-2,3-Epoxysqualene. Based on the findings, OE is a potential drug candidate for alcohol dependence.
A Network Pharmacology of Camellia sinensis (Green Tea)
Authors: Wahyuni Sri , Jamil Ahmad Shobrun , Muchlisin M Artabah
Published: November 2023

Network pharmacology focuses on the therapeutic concept of one-target-one-drug to network-target-components to combat complex diseases. This research uses bioinformatics and high-throughput screening methods to facilitate the prediction of various drug target networks based on the establishment of biological models and becomes more important in uncovering the underlying mechanisms of drug action. Tea (Camelia sinensis) is one of the most ancient and popular therapeutic drinks consumed throughout the world and prepared as a drink that can have many health effects. This research aims to determine the pharmacological network analysis of C. sinensis. The list of C. sinensis secondary metabolite compounds was obtained from the Dr. database Duke. Protein predictions associated with C. sinensis were obtained from SwissTargetPrediction. Pharmacological network analysis was performed with StringDB and KEGG enrichment. From the search results, 57 compounds were obtained. From network pharmacology analysis, 15 biomolecular pathways were obtained that were closely related to secondary metabolite compounds in C. sinensis. From the results of further analysis, it was found that C. sinensis has a role in the treatment of hypertension, cancer, and anti-inflammation.
Ecological Vitality and Posthuman Ethical Vision: Yann Martel’s Life of Pi
Authors:   The Korean Society For Teaching English Literature, Lee Chung-Hee
Published: November 2023

This paper aims to reexamine anthropocentric attitudes toward the non-human world and the commodification of nature driven by human self-centeredness. It also seeks to propose an affirmative posthuman ethics in Yann Martel’s Life of Pi. This novel illustrates how the castaway Pi undergoes a transformation, acquiring posthuman subjectivity as he escapes the grip of anthropocentrism and moves toward interconnectedness with both humans and non-humans while surviving in the Pacific Ocean with the Bengal tiger, Richard Parker. Pi’s experience of unity with nature signifies his growing understanding of the interdependent realities involving nature, the environment and animals. From the perspective of vitalist materialism, Pi comes to realize that he is an integral part of coexistence and coevolution within his relationship with nature and the non-human world. His subjectivity is oriented toward a sense of belonging to the universe. This novel not only prompts a shift in humanity’s environmental consciousness toward a postanthropocentric perspective but also encourages a harmonious balances between humans and non-humans. It suggests a vitalist posthuman ethics for a sustainable future. The relationality between humans and non-humans does not entail a return to exclusive privilege but rather points toward the interconnected facets of vitalist materialism. Pi’s transformation into a relational self with the non-human world invites readers to participate in the process of ‘becoming’ within generative environments and to pursue coevolution within vitalistic self-organizing assemblages.
Strengthening social work services in the health sectors of Low- and Middle-Income Countries: Taking lessons from social work actions/inactions in Covid-19 response in Nigeria
Authors: Agwu Prince
Published: November 2023

The social work profession is growing in many low- and middle-income countries (LMICs). In Nigeria, the profession recently got backed by an act of law, yet with persisting grey areas about its roles and responsibilities in the health sector, as well as many other sectors. The relegation of social work in containing Covid-19, and generally in Nigeria’s health sector, is largely lamented by published studies. As similar countries to Nigeria face this same challenge, there is a need to reflect on the limited roles of social work in health and what can be done to address this. A global agenda in the ‘Health in All Policies’ (HiAP) aligns with the need to consolidate social care and justice in healthcare. This commentary, through a review of literature and contextual experience, recommends a tripartite approach (union, community presence, and documented protocol), in scaling up social work presence in contexts where they struggle for identity
Intraspecific homofelisonyms
Authors: Ostroverkhaia Irina V.
Published: November 2023

The work presents an attempt to fill the gap in the study of intraspecific homonymy in felisonymy. The current research is aimed at determining the specifics of intraspecific homofelisonyms on a modern synchronous section of felisonymic material. The empirical base is made up of felisonyms (proper names of domestic cats; from Latin felis ‘cat’) obtained through a survey of respondents and continuous sampling from the Internet resources. A descriptive method and quantitative calculations are used to analyse the research base. Homonymy in felisonymy turns out to be quite a representative phenomenon. It manifests itself at the intraspecific level through numerous homooppositions, formed at the nomination stage, and includes homonymous felisonyms, which are determined by various nomination motives. The non-closed nature of the motivational base of intraspecific homofelisonyms is shown. The motivational base can be expanded due to additional nomination motives determined by the nominator’s preferences and felisonymic creativity. The specific features of intraspecific homofelisonyms are revealed. Being a felisonymic fragment of the nominator’s linguistic world picture, homofelisonyms represent in a concentrated form the onomastic features of felisonyms in general, namely: the principles underlying the naming process; possible formation by metaphorical and metonymic models; felisonymisation processes; derivational features of felisonyms; the difference between the namesake and homonymous felisonyms. The novelty of the present research appears to be an introduction of a certain layer of felisonymic units into scientific circulation and the presentation of their onomastic characteristics. The practical significance of the research is determined by the possibility of using its materials and conclusions in the development of zoonymy in general and felisonymy in particular, as well as in school and university teaching. Further prospects lie in the study of homonymous shortened felisonyms, which are derivative forms of the main proper names of domestic cats, which formed the empirical base of the current research.
Didactic potential of authentic advertising texts in Russian as a foreign language classes
Authors: Terskikh Marina V. , Zaytseva Olga A.
Published: November 2023

The didactic potential of the texts of modern commercial advertising in Russian as a foreign language classes is studied. In the theoretical part of study, the authors turned to the foreign experience of considering authentic materials as a means of developing communicative competence in teaching foreign languages. Approaches to the concept of authentic materials, the principles of their selection and algorithms of application in pedagogical practice are systematized. The advertising text is considered both as a means of improving linguistic competence and as a tool for integrating cultural components into the learning process, the advantages and disadvantages of advertising texts in terms of their linguo-methodological function are identified, and criteria for selecting promotional materials for classes in Russian as a foreign language are formulated. As a practical material, an algorithm for working with advertising texts at different levels of Russian language proficiency is presented, sample tasks are proposed for use in Russian as a foreign language classes in accordance with the three classical stages of working with text: preparatory (pre-demonstration), cognitive (demonstration) and reinforcing (post-demonstration). In the work, such research methods as the descriptive-analytical method, the method of systematization and classification, the design method, as well as the communicative method of teaching a foreign language are used.
“Galchonok” magazine as a space for children’s creativity
Authors: Lashcheva Anna S.
Published: November 2023

Introduction. The forms of work with readers’ creativity in pre-revolutionary children’s publications were not very diverse – the children’s literary and art magazine “Galchonok” (1911–1913) became an exception in this regard, providing readers with the opportunity to participate in the magazine’s creative projects. The purpose of the study is to analyze the editorial strategy of the Galchonok journal in terms of working with children's creativity. Innovative forms and principles of organizing and activating the creative activity of readers are examined, and the features of the communicative behavior of the editorial staff are simultaneously identified.
Materials and methods. The contents of the “Mailbox” section have been analyzed. Conclusions about the creative attitudes of the editors are made on the basis of essays about art published in the magazine, articles and notes with practical creative advice. The forms of publication of readers’ works, creative competitions and joint projects, as well as editorial comments to them, are considered in detail.
Result and Discussion. Public feedback on the works sent by readers and the playful communicative behavior of the editors contributed to the formation on the pages of “Galchonok” of a cross-cutting narrative dedicated to the creative activity of readers. It was extrapolated to other materials of the magazine, ensuring the interaction of fictional plots with appeals to the real activity of readers. At the same time, the organization of this activity was based not only on competitions for the best works, but also on projects in which the works of readers were given formality and conceptualization of a collective work.
Conclusion. The participation of readers in the creation of magazine materials led to the formation of a specific creative environment based on the principles of communication and play. The findings can add to the consideration of the continuity between the pre-revolutionary and Soviet stages of the development of children’s journalism in terms of interaction with the creativity of readers.
Russia vs Europe: N.Y. Danilevsky’s version. Possibilities of modern media interpretation
Authors: Ilchenko Sergey N.
Published: November 2023

The relevance of N.Y. Danilevsky’s work “Russia and Europe” is analyzed, which presents a study of the relations of these two subjects of history and geopolitics. The context of the analysis is both the tradition of Russian philosophical thought and journalism, and the media practice of the media in our time. The relevance of this issue is obvious today due to the dramatic geopolitical circumstances caused by the confrontation between Russia and the collective West in possible spheres of international relations: from military and informational to cultural and media. We consider the ontology of such relations on the example of cultural content and comes to the conclusion about the possibility and importance of introducing the theoretical premises of the Russian philosopher into the practice of modern domestic media. In his opinion, the current producers of domestic on-screen TV content are missing activation opportunities, relying mainly on up-to-date information and not delving, with rare exceptions, into the historical prerequisites for the emergence of antagonism between Russia and the West, Russia and Ukraine. Meanwhile, as the domestic experience of using historical ideologies shows, their actualization in the dominant public discourse, such a factor can play a decisive role in correcting mass consciousness in the direction of greater stabilization on the basis of distinct self-identification of citizens, which is based on a patriotic idea.
Reception of academic web texts: experimental study
Authors: Beloedova Anna V. , Dubrovskaya Tatyana V. , Kozhemyakin Evgeny A. , Tyazhlov Yan I.
Published: November 2023

The results of an experimental study are discussed, the purpose of which is to determine the general and specific principles of the reception of a academic text posted on the Internet, taking into account a group of communicative and technological factors, including the possibility of using interactive elements that control attention and perception of the text (affordances), and the use of extralinguistic material elements. Through a combination of methods – oculographic research, user experience analysis (UX-observation) and semi-structured interview – the data were obtained indicating the areas of attention and the structure of reading scientific Internet articles by users, as well as tactics of interacting with the text and understanding its content, depending on the presence or absence of affordances. The readers of scientific texts have academic affiliations and different experience of interacting with scientific materials. The authors come to the conclusion that it is necessary to take into account two groups of data in the course of studying the reception of a academic text: visual fixation on a text element / behavioral reaction to it and verbal representation of a text element during an interview. The paper draws preliminary inferences about how the readers perceive scientific Internet articles depending on the technological organization of the context. In conclusion, the requirements are offered for the organization of the main stage of the study.
Features of network video content naming
Authors: Sterlikov Dmitry A.
Published: November 2023

The active development of new media and the growth of their influence on the traditional media provokes interest in this sector on the part of researchers. And in connection with the activation of the consumption of audiovisual information, the video blogging sector is attracting more and more attention. The latter develops in a highly competitive environment. A blogger faces a difficult task – to win the attention of the audience in competition with other bloggers, platforms and reality. One of the means of solving this problem is naming. The name of the video content is able to attract an audience to it and promote the channel. The study analyzes the methods and techniques, which are used by the most popular video bloggers of Russian-speaking sector of the Internet in the field of naming. The conditions for the primary attraction of attention, as well as the means of emotional impact that bloggers use most often, are given.
The role of regional media in urban community development
Authors: Klemenova Elena N. , Fedoseeva Natalia I.
Published: November 2023

The relevance and novelty of the research are due to the insufficient study of the urban content phenomenon published on the pages of regional mass media. The purpose of the research is to determine the role of regional publications in urban community development, their involvement in the communicative space of urban environment. The empirical research material for the work is Rostov region mass media, including representatives of regional, district, city and corporate publications, as well as urban content produced by them. For the research, 7 periodicals are selected and 1550 publications of an urban nature are analyzed. The leading method of this research is a qualitative and quantitative analysis of the urban content of Rostov region press. The research formulates the conclusions that all the considered types of regional publications occupy an important place in the existing processes of urban media communication. The study also revealed that among the publications of the Rostov region, the regional media demonstrate unconditional involvement in the process of urban community development. More effective than other types of publications, they cover the problems of urbanization at different levels and influence the formation of public opinion, decision-making aimed at sustainable development of cities and the region as a whole.
Rare damage to the tendons of the posterior thigh muscle group. Clinical case
Authors: Mironov A. V. , Mironov V. S. , Shalin V. V.
Published: November 2023

Introduction. Hamstring tendon injury is a rare high-energy injury.

The aim of the work is to demonstrate a rare clinical case of simultaneous damage to the distal tendon of the semimembranous muscle and the distal tendon of the biceps femoris.

Object and methods. The patient is 55 years old, fell on the ice and sat in the "splits" position. Immediately after the injury, there was a sharp pain, the absence of active flexion of the right shin. She was treated conservatively. However, the pronounced pain syndrome and the lack of active movements forced the patient to do an MRI and consult a traumatologist.

Results and discussion. After performing an MRI and examination by a traumatologist, damage to the distal tendons of the semi-webbed and biceps femoral muscles was diagnosed. Surgical interventions were performed – tendon suture and tenodesis. Immobilization with a sharshnir splint with a bending angle of 80 degrees. After immobilization, a dosed extension of the knee joint with a hinge system with a frequency of 5 degrees per day was performed for 6 weeks. After carrying out a full complex of medical rehabilitation using physiotherapy and the Arthromot apparatus, the volume of movements is 0/0/180.

Conclusion. Early surgical treatment and competent rehabilitation measures allow you to fully restore the lost functions. Even with such rare injuries.
The complexities of complex treatment of a patient with widespread destructive pulmonary tuberculosis against the background of severe pulmonary bullous dystrophy after exogenous exposure to fine particles of coal dust in the anamnesis
Authors: Tarasov R. V. , Lepekha L. N. , Sadovnikova S. S. , Krasnikova E. V. , Barkova D. S. , Chesalina Ya. O. , Bagirov M. A.
Published: November 2023

An observation from practice is given – a staged surgical treatment of a patient with widespread destructive pulmonary tuberculosis with preXDR MBT against the background of severe bullous lung dystrophy after prolonged exogenous exposure to fine particles of coal dust in the anamnesis. Patient M., 42 years old, smoker, has been working as a loader at a railway station since the age of 20, unloading wagons with bags of coal at high temperatures without using personal protective equipment. He was ill with pulmonary tuberculosis 12 years ago, the original form: infiltrative tuberculosis of the upper lobe of the right lung in the phase of decay and insemination. He was treated with positive dynamics, was removed from the register 10 years ago, the real changes were revealed during a routine examination when applying for a vertebral hernia. According to computed tomography of the chest organs, a picture of fibrous-cavernous tuberculosis of the right lung with a system of polymorphic caverns with multiple foci of dropout in the left lung against the background of pronounced emphysema of both lungs was noted upon admission. He was admitted to the clinic with complaints of shortness of breath at rest (mMRC 3). The patient was selected therapy based on sensitivity data and individual intolerance. The patient underwent EC installation at the mouth of the upper lobe bronchus on the right, successfully, then at the mouth of the bronchus B6, the blocker was coughed up. Against the background of treatment, tuberculomas formed in the left lung. S1-2 resection of the left lung was performed. The patient suffered SARS CoV-2. After that, spontaneous pneumothorax occurred on the left, and therefore the pleural cavity was drained. Against the background of the lack of dynamics, a month after drainage, the patient was taken for revision of the left pleural cavity with suturing of defects, partial pleurectomy and decortication of the left lung. After 3 months, the patient had a bronchoblocker removed from the mouth of the ULB on the right and a combined resection of the right lung (upper lobectomy with S6) was performed, after which, in order to reduce the right hemithorax and reduce the overstretch of the right lung, thoracoplasty was performed with resection of the I-IV ribs on the right. Histological examination confirmed pulmonary tuberculosis against the background of exogenous exposure to fine particles of coal dust (by the type of hypersensitive pneumonitis of chronic course). As a result of treatment, the patient's symptoms of shortness of breath (mMRC 1) decreased, the patient was steadfastly abaculated and returned to a normal lifestyle.
Orolingual angioedema as a complication of systemic thrombolytic therapy with recombinant tissue plasminogen activator
Authors: Kovaleva E. A. , Korigova Kh. V. , Vyshlova A. I. , Shevchenko E. V. , Akhmatkhanova L. Kh.-B. , Ramazanov G. R. , Aliev I. S.
Published: November 2023

Orolingual angioedema is a rare, but extremely dangerous complication of systemic thrombolytic therapy with recombinant tissue plasminogen activator, the incidence of which reaches 2.2-5.1 %. Orolingual angioedema is a life-threatening condition, as it can lead to airway obstruction and asphyxia. An analysis of a clinical case of orolingual angioedema as a complication of systemic thrombolytic therapy using a recombinant tissue plasminogen activator is presented, risk factors for its development and treatment methods are presented. Orolingual angioedema is a rare life-threatening complication of systemic thrombolytic therapy with recombinant tissue plasminogen activator. It is necessary to assess the severity of edema every 30-60 minutes after systemic thrombolytic therapy in order not to miss the moment of escalation of the process. For the treatment of orolingual angioedema, antihistamines, glucocorticosteroids and adrenaline are used, in case of progressive edema and impaired airway patency, emergency tracheal intubation is performed, followed by artificial ventilation of the lungs.
Bonuszahlungen an Manager : Gerechtigkeitsurteile und betriebliche Folgewirkungen
Authors: Struck Olaf , Dütsch Matthias , Gückelhorn Cathrin , Hay Sabrina , Stephan Gesine
Published: November 2023

Gut 50% der Beschäftigten beurteilen Bonuszahlungen an Geschäftsführer in ihrem Unternehmen als ungerecht. Dies zeigt eine neue repräsentative Befragung, die diesem Aufsatz zugrunde liegt. Ziel der Befragung ist es zu ermitteln, welches die Ursachen dafür sind, dass Bonuszahlungen als gerecht oder als ungerecht beurteilt werden. Zudem wurde gefragt, ob und unter welchen Bedingungen Bonuszahlungen zu (negativen) innerbetrieblichen Folgewirkungen, wie etwa Kooperationsverweigerung mit der Geschäftsführung oder Verringerung der Arbeitsmotivation, führt? Verdeutlicht wird, insbesondere Verteilungskriterien wie die Höhe der Bonuszahlungen und Kriterien der Beitragsgerechtigkeit beeinflussen die Gerechtigkeitsurteile und die innerbetrieblich beobachteten Folgewirkungen, nicht jedoch Merkmale der sogenannten Verfahrensgerechtigkeit wie Informiertheit oder Mitwirkungsmöglichkeiten.
EFFECT OF POST MORTEM INTERVAL TOWARD Β-TRYPTASE AND CHYMASE EXPRESSION OF ANAPHYLACTIC HEART MAST CELLS
Authors: Susilo Imam , Putra Bilqisthi Ari , Yudianto Ahmad
Published: November 2023

Background: The effects of post mortem interval on tryptase levels are unclear and have been challenging to quantify due to limited and at times contradictory research. Purpose: Analyze the effects of Post Mortem Interval (PMI) due to anaphylactic shock on the expression of β-tryptase and mast cell chymase in the heart organ. Method: This type of research was an experimental study with a randomized block design (RBD) with the same subjects and a time series for 24 hours, using 5 (five) rabbits. The measurement of β-tryptase and chymase expression was based on immunohistochemical IRS (immunoreactive score) in the heart organs of rabbits experiencing anaphylactic shock sensitization and induction of anaphylactic shock using ovalbumin. Result: Based on the results of statistical tests using univariate analysis, there was a relationship between the length of death (post mortem interval) and the expression of mast cells β-Tryptase and cardiac chymase (p-value = 0.006) and chymase (p-value = 0.002) with (p-value <0.05). The effective test time with β-tryptase markers using cardiac organs was prone to long death time of 0 - 15 hours. The effective check-up time with chymase markers using the heart organ was at a long time of death of 9 hours. Conclusion: The results of the study showed that tryptase and chymase could be used as markers of anaphylactic shock.
Comparative Reproducibility Analysis of Thoracic Aorta Morphometric Parameters According to Computed Tomography and Magnetic Resonance Angiography
Authors: Varlamova Yu. V. , Saushkin V. V. , Ryumshina N. I. , Panfilov D. S. , Kozlov B. N. , Sazonova S. I.
Published: November 2023

Objective: to compare intra- and inter-operator reproducibility of thoracic aorta (ThAo) morphometric parameters, calculated by multislice computed tomography (MSCT) and magnetic resonance imaging (MRI).

Material and methods. The prospective study included 20 patients with ascending aorta (AAo) dilatation (≥45 mm). All patients underwent MSCT- and MRI-angiography in electrocardiogram-gated mode. Mean diameter (Dmean) and cross-sectional area (CSA) were measured at different ThAo levels in the systole and diastole along the inner contour of the vessel. All measurements were performed by two radiologists. Each of them took measurements twice at an interval of at least 1 month. The reproducibility of repeated measurements was studied using intraclass correlation coefficient.

 Results. The analysis of the systolic frame revealed significant differences between the methodsfor measuring Dmean (MRI: 42.5 (41.0–47.8) mm; MSCT: 37.7 (34.7–40.3) mm; p = 0.003) and CSA at the level of the sinotubular junction (MRI: 14.8 (12.7–17.9) cm2; MSCT: 11.4 (10.3–13.3) cm2; p = 0.009), AAo CSA(MRI: 17.6 (14.6–20.8) cm2; MSCT: 19.6 (16.7–21.5) cm2; p = 0.035) and Dmean at the level proximal to left subclavian artery (LSA) (MRI: 31.5 (31.0–34.0) mm; MSCT: 31.7 (27.3–32.9) mm; p = 0.041). For the diastolic frame, significant differences between the methods were observed when measuring AAo CSA (MRI: 17.0 (14.5–19.7) cm2; MSCT: 19.7 (15.3–21.8) cm2; p = 0.025), Dmean (MRI: 30.5 (29.3–32.8) mm; MSCT: 29.8 (27.1–31.3) mm; p = 0.05) and CSA at the level proximal to LSA (MRI: 7.5 (6.9–7.9) cm2; MSCT: 7.4 (5.9–7.8) cm2; p = 0.007), as well as CSA at the left atrium level (MRI: 4.9 (4.2–5.0) cm2; MSCT: 5.1 (4.67–5.5) cm2; p = 0.042). For MSCT-angiography, good intra- and inter-operator reproducibility of measurements at all ThAo levels was obtained. For MRI-angiography, there was a strong intra- and interoperator variability in determining Dmean and CSA at the levels of aortic arch and descending aorta.

Conclusion. Aortic cross-sectional area showed the best intra- and inter-operator reproducibility and comparability of measurements between MSCT- and MRI-angiography
Experience in Using Breast Single-Photon Emission Computed Tomography with 99mTc-MIBI
Authors: Shevkina S. P. , Zhestovskaya S. I. , Vyazmin V. V. , Shumilina N. Yu.
Published: November 2023

Objective: evaluation of the results of single-photon emission computed tomography (SPECT) with technetium-99m-methoxyisobutylisonitrile (99mTc-MIBI) in women with breast masses according to mammography (MMG) and ultrasound (US) examination in comparison with the results of morphology analysis.

Material and methods. SPECT with 99mTc-MIBI was performed in 11 women aged from 30 to 63 years (median age 40 [33.5; 46.5]) with BI-RADS (Breast Imaging Reporting and Data System) categories 4 or 5 mammary masses according to bilateral MMG and US diagnostics. Two patients underwent repeated SPECT and US to analyze the primary tumor response to neoadjuvant chemotherapy.

Results. With a multimodal approach to the diagnosis of breast tumors, including MMG and US, 11 pathological masses were identified. SPECT made it possible to find an additional mass that had not been previously visualized. All 12 masses were subsequently verified morphologically. With benign changes, hyperfixation of 99mTc-MIBI was not observed. SPECT allowed to assess the accumulation of the radiopharmaceutical in metastatically affected lymph nodes. However, the most sensitive method for detecting the axillary lymph node lesions is US. According to the results of repeated SPECT in 2 patients, no radiopharmaceutical accumulation was noted in mammary gland masses after two courses of neoadjuvant chemotherapy, but according to the histological examination, the tumor response was different: I and IV degrees of pathomorphosis according to G.A. Lavnikova

Conclusion. The experience of using mammary SPECT with 99mTc-MIBI confirms an increase in the accuracy of radiologic diagnosis of newly identified breast cancer, expands the possibilities of examination in cases of ambiguous MMG and US data, as well as the contraindications or patient’s refusal from magnetic resonance imaging.
To Help the Practitioner: Imaging of Ovarian Masses According to the O-RADS MRI Ovarian Malignancy Categorical Risk Scale
Authors: Aksenova S. P. , Nudnov N. V. , Slanskaya A. V. , Solodkiy V. A.
Published: November 2023

Objective: to study the informativity of the Ovarian-Adnexal Imaging-Reporting-Data System Magnetic Resonance Imaging (O-RADS MRI) in detection of ovarian cancer in the practice of a radiologist.

Material and methods. The study included 271 women who underwent pelvic magnetic resonance imaging (MRI) in the period from August to November, 2021. Two radiologists with 6-year (Researcher 1) and 2-year (Researcher 2) experience retrospectively analyzed MR images, in which all ovarian masses were evaluated according to O-RADS MRI categorical risk scale from 0 to 5. The analysis of true positive, true negative, false positive and false negative rates according to MRI data compared to the reference data (histology or 1-year follow-up) was performed.

Results. O-RADS MRI categorial risk scale had high diagnostic performance for the characterization of adnexal lesions (sensitivity 87.5% and 87.5%, specificity 97.84% and 96.75%, area under curve (AUC) 0.991 and 0.986 for Researchers 1 and 2, respectively), as well as good interreader agreement (Cohen’s kappa coefficient 0,83). Researchers’ mistakes were analyzed, as well as controversial issues of categorial affiliation of ovarian masses that caused false positive and false negative results. Visual aids for ovarian MRI in accordance with O-RADS MRI classification were made for quick orientation in the system to simplify creating the radiology report.

Conclusion. O-RADS MRI categorial risk scale proved to be a reliable working tool for the communication between radiologist and gynecologist-oncologist. However, the question of categorial affiliation of a number of nosological names that are not reflected in O-RADS MRI and require further study continues to be debated.
Mapping IgA Epitope and Cross‐Reactivity between Severe Acute Respiratory Syndrome–Associated Coronavirus and DENV
Authors: De-Simone Salvatore Giovanni , Napoleão-Pêgo Paloma , Lechuga Guilherme Curty , Carvalho Joao P.R.S. , Monteiro Maria Eduarda , Morel Carlos Medicis , Provance David William
Published: November 2023

Background: The newly introduced COVID-19 vaccines have reduced disease severity and hospitalizations. However, they do not significantly prevent infection or transmission. In the same context, measuring IgM and IgG antibody levels is important, but it doesn't provide information about the status of the mucosal immune response. This article describes a comprehensive mapping of IgA epitopes of the S protein, its cross-reactivity, and the development of an ELISA-peptide assay. Methods: IgA epitope mapping was conducted using Spot-synthesis and sera from RT-qPCR COVID-19-positive patients. Specific and cross-reacting epitopes were identified, and an evolutionary analysis from the early Wuhan strain to the Omicron variant was performed using bioinformatics tools and a microarray of peptides. The selected epitopes were chemically synthesized and evaluated using ELISA-IgA. Results: 40 IgA epitopes were identified, with 23 in S1 and 17 in the S2 subunit. Among these, at least 23 epitopes showed cross-reactivity with DENV and other organisms and 24 with other associated coronaviruses. Three MAP4 polypeptides were validated by ELISA, demonstrating a sensitivity of 90-99.96% and a specificity of 100%. Among the six IgA-RBD epitopes, only the SC/18 epitope of the Omicron variants (BA.2 and BA.2.12.1) presented a single IgA epitope. Conclusions: This research unveiled the IgA epitome of the S protein and identified many epitopes that exhibit cross-reactivity with DENV and other coronaviruses. The S protein of variants from Wuhan to Omicron retains many conserved IgA epitopes, except for one epitope (#SCov/18). The cross-reactivity with DENV suggests limitations in using the whole S protein or the S1/S2/RBD segment for IgA serological diagnostic tests for COVID-19. The expression of these identified specific epitopes as diagnostic biomarkers could facilitate monitoring mucosal immunity to COVID-19, potentially leading to more accurate diagnoses and alternative mucosal vaccines.