bluuebunny/crossref_metadata_2025 huggingface dataset:
Case Report: A Fatal Case of Latent Melioidosis Activated by COVID-19
Authors: Gulati Uday , Nanduri Ananya C. , Juneja Prateek , Kaufman David , Elrod Mindy G. , Kolton Cari B. , Gee Jay E. , Garafalo Kristen , Blaney David D.
Published: February 2022

Melioidosis, endemic in Southeast Asia and Northern Australia, is an uncommon but frequently fatal opportunistic infection caused by the Gram-negative saprophyte Burkholderia pseudomallei. We describe the first reported case of activation of latent melioidosis concurrent with COVID-19-associated lymphopenia and neutropenia in the setting of poorly controlled diabetes. A 43-year-old HIV-positive, diabetic man presented to the emergency department with persistent chills and progressive dyspnea. He was admitted for hypoxia. Chest X-ray showed bilateral parenchymal infiltrates suspicious for COVID-19. Shortly after admission, he became acutely encephalopathic, had a generalized seizure, and was transferred to the intensive care unit after intubation. Further workup showed severe neutropenia and lymphopenia. The patient received empiric antimicrobial coverage and was found to be severe acute respiratory syndrome coronavirus 2 positive. He deteriorated rapidly with refractory shock and persistent hypoxemia, and died 40 hours after admission. Blood cultures and sputum cultures obtained via bronchoalveolar lavage returned positive for Burkholderia pseudomallei. Given confirmed compliance with antiretrovirals, stable CD4 counts, and no recent foreign travel, the patient likely contracted the B. pseudomallei infection from travel to Southeast Asia many years prior and only became symptomatic after succumbing to severe acute respiratory syndrome coronavirus 2 infection. This case highlights the importance of considering activation of latent opportunistic infections by COVID-19 in immunocompromised patients.
Advanced Introduction to Law and Psychology
Authors: Tyler Tom R.
Published: February 2022

Leading scholar Tom R. Tyler provides a timely and engaging introduction to the field of law and psychology. This Advanced Introduction outlines the main areas of research, their relevance to law and the way that psychological findings have shaped – or failed to shape – the corresponding areas of law. Key features include focus on the relevance of psychological theories to topics in law, emphasis on the institutional realities within which law functions and discussion of the problems of bringing research findings into the legal system.
The Impact of Oil Prices on Inflation and GDP in Sri Lanka: An Econometrics Approach using Eviews
Authors: Jayarathna R.M.G.S
Published: February 2022

The study seeks to measure the influence of world oil prices on inflation and GDP in Sri Lanka using monthly data from 2000M01 to 2020M12. All variables are integrated in the same order and satisfy the precondition of the Johansen cointegration test, according to the Augmented Dickey Fuller unit root, Philips and Perron unit root, and Correlogram tests. There is a long-run association between oil price, inflation, and GDP, according to the Johansen cointegration test. Then, using Vector Error Correction Model (VECM), it was discovered that while there is a long-run causal relationship between oil prices and inflation, there is no short-run causal association. There is also a long-run causality from oil prices to GDP, but no short-run connection. Inflation granger causes GPD, and oil price granger causes inflation rate, according to the Granger causality test. The results of a variance decomposition analysis revealed that oil price shocks have little impact on inflation fluctuations, both in the short and long run. In the short run, an increase in oil prices will not have much of an impact on GDP fluctuations, but in the long run, an increase in oil prices will have a significant impact on GDP fluctuations.
A Review on Hill Climbing Optimization Methodology
Authors: Sathiyaraj Chinnasamy , Ramachandran M , Amudha M , Kurinjimalar Ramu
Published: February 2022

The activity of walking through hilly country for pleasure. He is an avid athlete and loves mountain walking. Mountaineering is a terrifying quest used for mathematical optimization problems in the field of artificial intelligence. Given a large input and a good horistic function, it tries to find a good enough solution to the problem. The mountaineering algorithm consists of three parts, where the global maximum or optimal solution cannot be reached: the local maximum, the ridge and the plateau. The trek is not complete or optimal, the time complex of O (∞) but the space complex of O (b). There is no special processing data system as mountaineering rejects old nodes. Trekking in the Alps or other high mountains. This is not an efficient method. This does not apply to problems where the value of the horticultural function suddenly decreases while the solution is in view. First-choice trekking enables balanced trekking by randomly creating heirs until something better than the current situation develops. Whenever this is a good strategy there are many (e.g., thousands) heirs in a state. So the first preferred mountain climbing is a special type Random mountain climbing. Description. This is a robust mountaineering algorithm. A person is initiated approximately. When the individual reaches a local optimal state a new solution is created approximately and mountaineering begins again. The best first search is a traversal technique, which checks which node is the most reliable and decides which node to visit next by checking it. To this end, it uses the appraisal function to determine travel. Climbing is used to describe traditional ‘siege’ techniques, where you will climb the mountain several times before being driven to the summit. Albinism, on the other hand, focuses on 'fast and light' climbs. Free climbing was created to describe any style of climbing that is not AIDS related. ... In free climbing, the climber moves the wall under their own force without the use of any special gear (except for the climbing shoes) to help them move upwards. Climbers can only survive for a short time in the 'death zone' at 8000 m and above, where there are numerous challenges. Deep cracks, avalanches, cliffs and snowflakes make the high form of trekking a very dangerous endeavor. Caldwell and George's son use headlamps to illuminate their way, climbing at night when the temperature is cold - meaning their hands sweat less and there is more friction between their rubber shoes and granite. According to the author, climbing mountains is a very difficult task for people and they enjoy crossing obstacles. Mountaineering is neither complete nor optimal, the time complex of O (∞) but the space complex of O (b). There is no special processing data system as mountaineering rejects old nodes
Statistička analiza kretanja broja novih članova obveznih mirovinskih fondova i uplata doprinosa u drugi stup mirovinskog osiguranja u Republici Hrvatskoj (2011. – 2020.)
Authors: Dajak Tamara , Papić Milan , Vudrić Nenad
Published: February 2022

Mirovinski fondovi predstavljaju značajne institucionalne investitore u Republici Hrvatskoj, kojima investicijski potencijal kontinuirano raste. U posljednjih desetak godina udio
njihove imovine u ukupnoj imovini financijskog sustava porastao je s nešto manje od 5 %
na 17 %, dok imovina obveznih mirovinskih fondova čini oko 27 % hrvatskog BDP-a. Članstvo u obveznim mirovinskim fondovima obvezno je za zaposlene osobe mlađe od 40 godina, a sredstva koja se izdvajaju na temelju doprinosa za mirovinsko osiguranje iznose 20
% bruto plaće zaposlenika. Ta se sredstva izdvajaju tako da se 15 % izdvaja u prvi stup obveznog mirovinskog osiguranja na temelju generacijske solidarnosti (MIO I), a 5 % u drugi
stup obveznog mirovinskog osiguranja na temelju individualne kapitalizirane štednje (MIO
II). U ovome radu napravljena je statistička analiza kretanja broja članova u obveznim mirovinskim fondovima (OMF) kao i dinamika uplata doprinosa za mirovinsko osiguranje na
temelju individualne kapitalizirane štednje u drugi stup mirovinskog osiguranja (MIO II) u
RH za razdoblje od 2011. do 2020., kao i međusobni odnos i utjecaj promatranih varijabli.
Sive zone kod odgovornosti za štetu nastalu naletom vozila na divljač
Authors: Ćesić Zlatko , Šutić Milan
Published: February 2022

Porast broja motornih vozila i sve veća mreža prometnica neminovno za sobom povlače
porast šteta nastalih naletom vozila na divljač. Postojeće normativno uređenje lovoovlaštenike ab initio stavlja u kudikamo bolji procesnopravni i materijalnopravni položaj nego što
je to bilo posrijedi kod zakonskih rješenja koja su prethodila sada vrijedećem, a vozače, argumentum a contrario, u nepovoljniji i zahtjevniji procesnopravni i materijalnopravni položaj. Zakonodavac brojne sive zone prepušta sudovima koji bi u takvim okolnostima trebali
tumačiti nejasne odredbe i popunjavati pravne praznine. U ovome radu autori su nastojali
utvrditi koje su to sive zone izvanugovorne odgovornosti za štetu nastalu naletom vozila
na divljač i predložiti moguća normativna rješenja de lege ferenda za njihovo otklanjanje.
Gypsies and Travellers in Housing
Authors: Smith David M. , Greenfields Margaret
Published: February 2022

This is the first published research from the UK to address the neglected topic of the increasing settlement of gypsies and travellers in conventional housing. It highlights the complex and emergent tensions and dynamics inherent when policy and popular discourse combine to frame ethnic populations within a narrative of movement.
An Economic Analysis of PM Kisan Scheme in Ri-Bhoi District of Meghalaya State
Authors: Choudhury Anju
Published: February 2022

"The PM Kisan scheme enables to support the financial needs of all land holding farmers in order to purchase various inputs timely and ensure proper crop health and adequate yields. Keeping this in view, a study was conducted to analyse the economics of PM Kisan scheme for the 2020-21 Kharif season in Ri-Bhoi district of Meghalaya. Primary data on cost and returns of the paddy crop (main crop) were collected by interviewing the farmers through personal visits with the help of an especially structured and pre-tested schedule. From the cost and returns calculated, it was found that there was an increase of 2.14 per cent, 4.74 per cent and 8.71 per cent on the cost of cultivation, gross returns and net returns, respectively for beneficiaries than that of the non-beneficiaries in Kharif 2020-21. This shows farmer distress has reduced to extent and beneficiary farmers are willing to spend more for better returns. From the study it can be concluded that the beneficiary farmers are somewhat benefited from the PM-Kisan scheme"
Penerapan Metode Smart Dalam Menentukan Mata Kuliah Terfavorit Pada Kampus Merdeka Di STIKOM Tunas Bangsa
Authors: Fachrur Rozy Muhammad , Sudahri Damanik Irfan , Syahputra Saragih Ilham
Published: February 2022

Saat ini kreativitas dan inovasi menjadi kata kunci penting untuk memastikan pembangunan Indonesia yang berkelanjutan. Para mahasiswa yang saat ini belajar di Perguruan Tinggi, harus disiapkan menjadi pembelajar sejati yang terampil, lentur dan ulet. Kebijakan Merdeka Belajar – Kampus Merdeka yang diluncurkan oleh Menteri Pendidikan dan Kebudayaan merupakan kerangka untuk menyiapkan mahasiswa menjadi sarjana yang tangguh, relevan dengan kebutuhan zaman, dan siap menjadi pemimpin dengan semangat kebangsaan yang tinggi. Proses pengambilan data diperoleh dengan cara membagikan kuisioner dan observasi secara langsung.Dengan variable jumlah SKS, peluang pekerjaan, dan alasan mahasiswa dalam mengambil mata kuliah pada kampus merdeka. Hasil penelitian ini berupa mata kuliah yang akan diambil berdasarkan mata kuliah yang ada pada Kampus Merdeka di STIKOM Tunas Bangsa.
Pengembangan Teknologi E-Marketplace Jasa Penjahit di KOTIM dengan Metode SMART dan Location Based Services
Authors: Atiaini Cicilia Elfrida , Mustaqiem Mustaqiem , Minarni Minarni
Published: February 2022

The rapid development of technology can make things easier, faster and more comfortable. The use of technology itself does not only benefit one party but also all parties, indirectly we must follow technological developments so that we can be superior to others. And with the virtual world created because of the development of internet technology, it is what indirectly creates a separate market or trading platform which is now commonly referred to as an e-marketplace. As the market in its conventional sense, which is a place where sellers and buyers meet directly, while in e-marketplaces, sellers and buyers meet in cyberspace and are not limited by space or time. This research was conducted using the SMART method and Location Based Services. Data collection techniques were carried out by means of observation and literature study. From the results of the research on the Development of E-Marketplace Technology for Tailor Services in Kotim with the SMART method and Location Based Services, this is an e-marketplace for tailor services for tailor service providers to market or sell their services in the Kotim area, the program created can be used for tailor service users. in finding a tailor's location, and the program created can also be used for tailor service users in determining which tailor to choose based on several assessments of the existing tailor criteria
Penerapan Data Mining Dalam Pengelompokan Data Member Card Mitra10 Untuk Meningkatkan Rewards Terhadap Konsumen dengan Metode Fuzzy Subtractive Clustering
Authors: Wibowo Yudi
Published: February 2022

Data clustering of Mitra10 member card, it is only based on the payment day by customer. And the total point only based on 0,25% calcutation of each payment. This is not so efficient knowing that there are so many ungrouping data that can be use for increase the rewards to the customer. In order to clustering the data of member card total point, it need a method of data clustering. The method election really affecting the result of data clustering. After all of the member card Mitra10 data transformed to the number form, then the datas can be grouping to fuzzy subtractive clustering algorythm. The data need to divided to some cluster : Select the amount of the cluster. In this research the data will be divided to 3 cluster. Select the center point of each cluster and fisrt center point selected randomly to generate main center point of each cluster. One data will be part of one cluster that has the smallest distance from the center cluster. Example for the first data, smallest distance get by cluster 1, so that the first data will be member of cluster 1. And so for the second data , smallest distance in cluster 3, so it will be member of cluster 3. In this iteration, center point of each cluster does not changed and there is no moving data to another cluster. Cluster 1 result: Has center  (1,413, 1,195, 1,695) cluster 1 dominated by the bronze group. Cluster 2 result: Has center (2,658, 1,219, 1,585) cluster 2 dominated by the silver group. Cluster 3 result: Has center (4, 1,8, 3) cluster 3 dominated by the silver group
How do Climate Change, Environmental Degradation and Economic Growth affect CropsProduction in Pakistan?
Authors: Chaudhry Imran Sharif , Aslam Abdul Rehman , Farooq Fatima , Faheem Muhammad
Published: February 2022

Climate change has become one of the most imperative problems of this century. Climate change is a grave global threat, and Pakistan has been ranked eighth on the list of countries most vulnerable to climate change by the German watch Global Climate Risk Index. The increasing amount of carbon dioxide (CO2), the foremost contributor to environmental degradation, seems to provoke this problem. Agriculture-based economies have always been dependent on the vagaries of nature and climate. Present study analyses the climate change,  environmental degradation, input index and economic growth impact on crops production in Pakistanfrom 1977 to 2016. Our study employsAuto Regressive Distributed Lag Model (ARDL) to check the long run association among the variables. The results shows that positive association among climate change and crops production in the longrun.On the behalf of results policymakers must drive attention to adopt advanced cultivation processes using farming practice through international research institutions' assistance to further improve crops production in Pakistan.
Pengendalian Kualitas Pengolahan Kulit Uptd Kota Padang Panjang Menggunakan Metode Six-Sigma
Authors: Farid Mohammad , Yulius Henny , Irsan Irsan , Susriyati Susriyati , Maulana Bobby
Published: February 2022

Pengendalian kualitas merupakan langkah penting yang dilakukan untuk meminimalisasi produk cacat. Setiap perusahaan baik jasa maupun manukfaktur berusaha agar kualitas produknya tetap terjaga. Salah satunya adalah pada UPTD pengolahan kulit Kota Padang Panjang yang bergerak dalam bidang jasa pengolahan kulit. Berdasarkan hasil survei lapangan, maka didapatkan adanya kecacatan yang terjadi selama proses pengolahan kulit seperti kulit robek dan lainnya. Penyebab Defect pada proses pengolahan kulit dipengaruhi oleh beberapa faktor seperti: manusia, material, lingkungan dan mesin. Tujuan dari dilakukannya penelitian ini adalah untuk menerapkan pengendalian kualitas dengan menggunakan metode Six Sigma dan mengidentifikasi faktor apasaja yang menyebabkan timbulnya Defect pada proses pengolahan kulit dengan menggunakan pendekatan Six Sigma. Pendekatan Six Sigma dilakukan dengan merumuskan Define, Measure, Analyze, Improve, Control (DMAIC) yang terjadi pada perusahaan. Berdasarkan pengolahan, maka didapatkan nilai Sigma pada proses pengolahan kulit tahun 2018 yaitu 3,086  3.0 dengan nilai DPMO 56398.10 unit untuk sejuta produksi. Nilai ini berada pada level 3 Sigma artinya perusahaan perlu meningkatkan kualitas proses pengoalahan kulit untuk mencapai Zero Defect.
The Effect of Non-Price Policies on Household Tobacco Consumption Among the Filipino Youth in City of Manila
Authors: Marcelino Jillianne O. , Janelle D. Waje Thea , R. Cabauatan Ronaldo
Published: February 2022

Tobacco consumption, including cigarette smoking, has a significant and increasing global public health burden.
Despite recent declines in incidence, its adverse effects on human health increases the risk of several cancers. This
study explained the non-price strategies that directly influence smokers' intake and initiation and the problem of
long-term tobacco exposure by second-hand smokers and those affected by the media or their environment. Higher
cigarette taxes and tighter regulations and enforcements, restricting who can purchase tobacco products, are
prevention examples that equate to the cessation process. The research contributed to the area of study regarding
the optimal control on tobacco use since it examined the findings of the performed survey to understand the
influence of non-price strategies such as graphic health warnings on the young smoking intention. To substantiate
the relationship between non-price policies and tobacco usage, it explores the purposively selected participants for
the study, Filipino male or female youth smokers and non-smokers with an age qualification between 15 and 30
years old. The study illustrates that to promulgate awareness regarding the risks of vicious substance intake, the
government must implement substantial compliance and aversion through specific indicators from this research
model.
Keywords: Youth, tobacco consumption, cessation, risk aversion, illness, health warnings, tobacco policies,
smoking
Dark triad, risk propensity and interpersonal relationship satisfaction in clients with substance use disorder
Authors: Irfan Rida , Latif Sara , Noor Naheed
Published: February 2022

Abstract
Objective: To examine the relationship of drug addicts with personality triad, risk propensity and interpersonal relationship satisfaction.
Methods: The correlational study was conducted from September 2019 to February 2020 in different hospitals of Lahore, Pakistan, and comprised male drug addicts aged 18-30 years. Data was collected using the Dark Triad of Personalityscale, the Risk Propensity Scale and the Interpersonal Relationship Satisfaction Scale. Data was analysed using SPSS 21.
Results: There were 100 men with a mean age of 25.03+/-3.82 years.
Conclusion: Dark triad and risk propensity significantly predicted interpersonal relationship satisfaction, while narcissism did not predict interpersonal relationship satisfaction.
Key Words: Dark triad, Risk propensity, Interpersonal relationship satisfaction, Drug addicts.
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Comparing the effects of muscle energy technique and mulligan mobilization with movements on pain, range of motion, and disability in adhesive capsulitis
Authors: Razzaq Ayesha , Nadeem Rana Dilawaiz , Muhammad Akhtar  , Ghazanfar Mariam , Aslam Naeem , Nawaz Sadia
Published: February 2022

Objective: To compare the effect of muscle energy technique and Mulligan mobilisation with movement on pain, range of motion and disability in patients of adhesive capsulitis.
Methods: The single-blind, randomised controlled study was conducted at the Physiotherapy Department of Mayo Hospital, Lahore, Pakistan, from July to December, 2018, and comprised patients of either gender aged 30-70 years with adhesive capsulitis stage 2. The subjects were randomised using the lottery method into Mulligan mobilisation with movement group A, and the muscle energy technique grouo B. Conventional treatment, including hot packs and exercises like pulley rope exercise, wall climbing, and shoulder wheel, were part of both the groups. Each technique was applied five times per set, 2 sets per session 3 days a week for three weeks. Baseline and post-intervention readings were recorded for pain, range of motion and disability Using numeric pain rating scale, goniometer, and shoulder pain and disability index. Data was analysed using SPSS 23.
Results: Of the 70 individuals assessed, 64(91.4%) were included; 32(50%) in each of the two groups. The mean age in group A was 49.93±6.69 years, while in group B it was 49.17±8.92 years. Group A showed significantly better result compared to group B (p<0.05).
Conclusion: Muscle energy technique and Mulligan mobilisation with movement were both found to be effective, but the latter was significantly better compared to the former.
Clinical Trial Number: IRCT20200611047734N2 (https://www.irct.ir/trial/48851)
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Sitagliptin, a promising DPP-4 inhibitor for prevention of acute graft versus host disease
Authors: Jaffry Asra Arshad , Iflah Ansari  , Zainab Rauf
Published: February 2022

Madam, allogeneic hematopoietic stem cell transplant (HSCT) remains a life altering cure to exceptionally challenging diseases ranging from hematologic malignancies to primary immunodeficiencies and blood cancers. One of its adversities includes graft versus host disease (GVHD), a lethal immunologically mediated condition wherein the donor's T-cells attack the host's tissues. The presentation can be classified as acute or chronic. Acute GVHD is divided into four grades. Despite current prophylaxis, including a combination of calcineurin inhibitor with either methotrexate or sirolimus, the incidence of grade-II or higher GVHD is between 30% to 80%, with grade-IV GVHD approaching mortality rates up to 90%.1
A recent phase II trial by Farag et al. addresses the issue by introducing a novel combination of sitagliptin – a specific DPP-4 inhibitor used to manage type 2 diabetes in adults – along with tacrolimus and sirolimus for prevention of GVHD.2 Using the new blend, an overall marked reduction in the risks of grade-II to IV (5%) and grade-III to IV (3%) acute GVHD was shown, compared to previous studies using only sirolimus and tacrolimus.3 Moreover, no adverse effects were associated with the drug during the period of study.
Advancements in the field of HSCTs are particularly crucial in developing countries such as Pakistan. The high prevalence of consanguineous marriages and insufficient genetic counselling make the country especially vulnerable to diseases like thalassemia, bone marrow failure syndromes and immunodeficiency states. Up to 9000 children require transplantation each year due to the high prevalence of beta- thalassemia major.4 The situation is further complicated by limited resources and few stem cell transplant centres, which are limited to major cities.
Although HSCT efficiently treats numerous life-threatening conditions, only 719 patients underwent HSCT till mid-2017 cumulatively in Pakistan.4 In accordance with the aforementioned factors, the number of transplants performed heavily outnumbers their demand, making it essential to tackle a complication as deadly as acute GVHD. In a 2005 study conducted in Rawalpindi by Hashmi et al., the overall incidence of acute GVHD grade-II to IV after standard immunosuppressive therapy was 44.2%.5 While the results were comparable to other studies, the high f morbidity and mortality rates necessitates alternate treatment courses.
Sitagliptin, a locally manufactured, cost-effective drug, will be an appropriate choice of medication in Pakistan where average income amounts to a meagre US$1000 per year.4 However, randomized trials are needed to further investigate its role in the prevention of acute GVHD.
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An infrequent case of adult nasopharynx rhabdomyosarcoma with bony involvement: a case report
Authors: Tabe Rasool  , Salma Salman  , Faiza Ghuman  , Afshan Siddiqui  , Salman Niaz Ahmed  , Maria Akhtar
Published: February 2022

Rhabdomyosarcoma is a rare and highly aggressive malignancy arising from the striated skeletal muscle fibre. It is commonly a childhood tumour and rarely seen in adults. The most predominant part commonly involved is head and neck. We are reporting a rare case of a 54 year old adult male with Rhabdomyosarcoma of nasopharynx with a non specific presentation of weight loss for past four months, fever, a perianal abscess and backache since 10 days.
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Anthropologie et justice
Authors: Dupret Baudoin , Benalioua Mariam
Published: February 2022

Dans les travaux d’anthropologie portant sur la justice, les questions de la domination, des inégalités et des discriminations de genre ont focalisé l’attention. Privilégiant une approche critique plutôt que descriptive, cette focalisation a  entraîné la marginalisation de l’étude du fonctionnement ordinaire et concret de la justice. L’engouement pour la méthode ethnographique, voire praxéologique, permet d'entrevoir une inflexion de cette tendance.
Work Process and Hazard Analysis in Small-scale Gold Mining in Northern Philippines
Authors: Leung Ana Marie R. , Lu Jinky Leilanie
Published: February 2022

Introduction. Small-scale mining (SSM) is mining by individuals, groups, families, or cooperatives with minimal or no mechanization, often in the market's informal (illegal) sector. According to the Mines and Geosciences Bureau (MGB) in the Philippines, the gross production value of small-scale mining as of the 1st to 3rd quarter of 2020 was 0.5 billion pesos (1.05 billion USD).

Objectives. This study investigated the work process in small-scale mining in the northern part of the Philippines. It documented the occupational hazards that small-scale gold miners are exposed to in each of the work processes.

Methods. The target population is a community in the northern Philippines where the majority of the males are engaged in small-scale gold mining. This qualitative study used work observation and hazards analysis tools to investigate small-scale miners' work processes and hazard exposures.

Results. The most widely employed mining technique in the target community is dog-hole mining consisting of several sub-processes: tunneling, ball milling, and gravity concentration, cyanide leaching, and smelting. The occupational hazards identified were noise exposure from the dynamite blast, temperature extremes, and exposure to dust from dynamite blasting. The small-scale miners were subjected to prolonged crouching and bending, handling tools, and carrying heavy sacks filled with mineral ores. The miners resorted to improvised protective equipment such as wearing sleeveless shirts and drinking water for temperature extremes, distancing themselves from the mining blasts during dynamite blasting, and intermittently used carts with manual handling to transport ores packed in sacks. In the ball milling and gravity concentration process, machine-related accidents such as cuts from the crusher were observed. In cyanide leaching, which uses massive amounts of cyanide, the most prevalent hazards were heat, dust, and chemicals such as cyanide fumes. The risks included smoke from burning ore and coal and exposure to borax and nitric acid fumes in the smelting process.

Conclusion. This study documented the work process in small-scale gold mining and the hazard exposures in this type of informal industry. It is suggested that the local and national governments implement intervention programs for occupational health and safety measures, and social security nets are provided for the small-scale miners in Itogon, Benguet.
Analysis of Transport and Vehicular Crash Cases Using the Online National Electronic Injury Surveillance System (ONEISS) from 2010 to 2019
Authors: Lu Jinky Leilanie , Herbosa Teodoro J. , Lu Sophia Francesca
Published: February 2022

Introduction. Around 1.35 million people die due to road traffic accidents yearly. In the Philippines, there is an increasing trend of mortality and morbidity caused by road crashes.

Objective. The objective of the study is to show the epidemiology of transport and vehicular crash (TVC) cases in the Philippines using the Department of Health (DOH) Online National Electronic Injury Surveillance System (ONEISS) from 2010 to 2019.

Methods. We used data from ONEISS, a web-based system to electronically capture injury-related data from health facilities, store data in a centralized and secure location, process and consolidate data, and transform this data into meaningful information. For Transport and Vehicular Crash cases, risk factors such as drug use, alcohol use, mobile phone use, seatbelt, and helmet use are included. There are also data on vehicle type, place of crash, and activity. Descriptive and inferential statistics were computed to explore and analyze the ONEISS dataset, particularly the epidemiology of transport and vehicular crashes (TVC).

Results. There were a total of 296,760/894,989 (31%) patients admitted due to transport and vehicular crash (TVC) based on the 10-year data from ONEISS (2010–2019). There was an increasing trend in the number of transport/ vehicular crashes (TVC) during this period, with an average increase of 25.58% cases per year. Most victims were drivers (45.6%), males (72.5%), and from the younger age group (0-30 years old). Fatal crashes were observed to occur from 6:00 pm to 5:00 am while most accidents occurred during leisure activities (32.5%). The highest reported contributing factor was drunk driving (n = 25,537). There was observed low compliance on the use of vehicular safety equipment. The most common types of injuries for the TVC victims were abrasions, contusions, burns, and concussions while the vehicle most involved in TVC was the motorcycle. Motorcycle use was found to be associated with worse emergency room (ER) outcomes (p <.0001) and the highest injury types such as multiple injuries, abrasion, avulsion and burn. Alcohol use was also significantly associated with multiple injuries, abrasion, avulsion, burn, open fracture, open wound, and amputation (p < 0.05).

Conclusion. The trend of road traffic vehicular crashes affecting mainly the younger population has economic repercussions. Motorcycles are also most involved in crashes, hence, the need for motorcycle safety laws in the country. There is also a need to strengthen current laws and legislation governing road safety and to focus on structuring a systematic post-crash response for both the local government and hospitals throughout the Philippines.
Effects of Dicamba Herbicide on Tubercularia ulmea Canker Development
Authors: Jackson Marcus B. , Stack Robert W.
Published: February 2022

Dicamba (3,6-dichloro-o-anisic acid) herbicide was applied to the roots of potted Siberian elm(Ulmus pumila)and Russian-olive(Elaeagnus angustifolia)trees in a greenhouse. Five herbicide concentrations were used: equivalent to rates of 0 (0), 93 (1/12), 140 (1/8), 280 (1/4), and 1,121 (1) g/ha (lb/ac) active ingredient. Two weeks after herbicide application, each tree was inoculated with a single isolate of the canker-causing fungusTubercularia ulmea. The experiment was repeated using two differentT.ulmeaisolates. Leaf cupping, a symptom of dicamba exposure, was evident two to three weeks after herbicide application. Symptoms occurred at rates of 140 g/ha (1/ 8 lb/ac) and above in the Siberian elms and the 1,121 g/ha (1 lb/ac) rate in the Russian-olives. All fourT.ulmeaisolates caused cankers, with canker size differences between fungal isolates and between tree species. None of the herbicide treatments increased or decreasedT.ulmeacanker size.
O FAUSTO NAS AMÉRICAS: MEFISTÓFELES E LEGBA NA ENCRUZILHADA
Authors: Roque Isabel Rebelo
Published: February 2022

O texto parte da figura mítica do Fausto, cuja origem histórica teria se dado na Alemanha, e percorre brevemente suas reverberações na própria Alemanha e em outros países europeus, como a Inglaterra e a França. Nessa cartografia de origem, serão caracterizadas algumas das mutações do Fausto em sua pactuação com Mefistófeles, das primeiras narrativas moralistas até a inserção na modernidade e a atualização do mito em novas incorporações e linguagens. Faremos uso do conceito de tecido fáustico, de Jerusa Pires Ferreira, para então acompanharmos o tema fáustico até as Américas. Nesse recorte, o foco estará na investigação de um certo Fausto potencialmente presente na América do Norte, mais exatamente no sul-sudeste dos Estados Unidos, onde nasceu o blues. Para tratarmos do surgimento do blues, porém, não temos como deixar de fora os chamados “mitos da encruzilhada”, trazidos da África Ocidental pelos negros escravizados.
“E FOI ASSIM QUE EU E A ESCURIDÃO FICAMOS AMIGAS” UMA HISTÓRIA EM FORMATO DE POEMA PARA PAIS E MÃES E FILHOS(AS) LEREM JUNTOS
Authors: Fontana Drum Marluci
Published: February 2022

E se um livro pudesse acalantar o coração de uma criança que tem medo do escuro? E se esse livro contasse uma história em formato de poema e não só convencesse os pequenos que o receio é comum e que até os adultos o sentem em certos momentos, mas também os encantasse com os versos rimados a cada virar de página? É dessa forma que Leandro Roque de Oliveira, o Emicida, rapper, cantor, letrista, compositor e autor da obra “E foi assim que eu e a escuridão ficamos amigas” brinca com a imaginação e conta uma bela história em forma de poesia.
METAFICÇÃO HISTORIOGRÁFICA E GÊNERO: UMA LEITURA DE CARTA À RAINHA LOUCA, DE MARIA VALÉRIA REZENDE
Authors: Costa Cindy Conceição Oliveira , Lopes Sebastião Alves Teixeira
Published: February 2022

Este artigo objetiva analisar aspectos ligados aos estudos de metaficção historiográfica e gênero no romance Carta à rainha louca (2019), de forma a examinar, através da protagonista-escritora, uma visão feminina do Brasil do século XVIII. Apoiamo-nos nas teorias de Hutcheon (1991; 1984), Kause (2010), Scott (1995), Santos (2020), Del Priore (1994), entre outras. Como se sabe, a História foi por muito tempo narrada fundamentalmente sob uma perspectiva europeia, branca e masculina, portanto, a metaficção historiográfica, ao se voltar para a História, encara-a de modo diferente, através de perspectivas ex-cêntricas, como a de uma mulher enclausurada e tida como louca, conforme apresentado no romance em apreço.
Pizotifen for the treatment of migraine. A systematic review and meta-analysis
Authors: Fragoso Yara Dadalti , Lopes Giullia C. Mangas , Santos Giovanna Marcilio , Carturan Paula , Martimbianco Ana Luiza C.
Published: February 2022

Introduction Pizotifen is an oral drug developed many years ago for the prophylaxis of migraine. Trials on pizotifen are decades old, and there has never been a systematic review and meta-analyses of data from these clinical studies. Methods This is a systematic review and meta-analyses on pizotifen's efficacy and safety for prophylactic migraine treatment. We considered for inclusion only randomized clinical trials (RCTs). A comprehensive electronic search was performed without language, date or publication status restrictions in the formal electronic databases, clinical trial registration platforms and grey literature. Results There were eight RCTs of pizotifen compared either to placebo or to other drugs. Very low certainty of evidence showed that pizotifen seems to be superior to placebo regarding clinical symptoms improvement (Relative risk [RR] 6.00; 95% Confidence interval [CI] 1.63 to 22.03; p = 0.007), but not inferior to naproxen, flunarizine, valproate or clonidine. Weight gain was the most frequent adverse event of pizotifen but there was no difference with placebo (RR 1.92; 95% CI 0.30 to 12.38; 2 RCTs; 142 participants; I2 = 67%; p = 0.49). Conclusion The RCTs of pizotifen were decades old. It is a safe and potentially efficacious inexpensive drug that deserves a better designed, modern clinical trial before being dismissed as an option for migraine therapy. PROSPERO Register: CRD42020194347.
Analysis of the prevalence of headaches subtypes in a specialized outpatient clinic in a municipality in medium-sized Minas Gerais
Authors: Ribeiro Estephanie Veronese , Rodrigues Gustavo Alvarenga , Araujo e Costa José Rafael , Pereira Julia Rodrigues , Assis Junior Marcelo Rodrigues , Jurno Mauro
Published: February 2022

Objective
To evaluate the prevalence of different subtypes of headaches in a tertiary referral clinic for headache care in the city of Barbacena.
Methods
A retrospective and descriptive cross-sectional cohort study that evaluated the medical records of 130 patients previously seen by a neurologist in January 2020 to March 2021 in the headache clinic.
Results
The mean age of patients was 42.5 years, most of them female (83.07%). Primary headaches were the most common, with migraine found in 73% of cases and tension-type headache (TTH) in 17%. Among secondary headaches, the most common subtype was headache attributed to a substance or its suppression (11%), followed by cases such as headache due to cranial neuralgia and central causes of facial pain (3%) and headache attributed to trauma or head and/or cervical injury (3%). All cases in which there was an association of diagnoses of headache subtypes were found in patients with migraine (100%).
Conclusion
This study defines the prevalence of headaches in a specialized outpatient clinic, confirming literature data that show migraine as the most common headache.
Migraine cure: a patients' perspective
Authors: Peres Mario Fernando Prieto , Serafim Alexandre , Oliveira Arão Belitardo de , Mercante Juliane Prieto Peres
Published: February 2022

Objective
To conduct a web-based survey concerning patient’s perspective in the migraine cure.
Material and Methods
A total of 1,102 patients fitting the International Classification of Headache Disorders (ICHD-3) migraine criteria, seeking medical care at the Brain Research Institute at Albert Einstein Hospital in Sao Paulo, Brazil, from January to December 2015, participated in the survey. The online-based survey was accessed via the institute’s website and consisted of demographic data, a description of migraine symptoms, diagnosis and treatment, and the patient’s opinion of migraine cure and which treatment they would consider taking.
Results
Migraine intensity was significantly higher in female participants than male participants. Chronic migraine tended to affect female participants more than male participants. There was a significant difference in the rate of migraine cure belief between patients with episodic and chronic migraine.
Conclusion
Some points that were important to migraineurs have been identified in this study. Ultimately, the findings of this study may facilitate the migraine treatment decision process, by providing a better understanding of patients’ perspectives and beliefs, thus creating a more friendly communication between migraineurs and care providers and hopefully, improving the quality of life of patients.
Red Ear Syndrome and migraine: case report and review of this peculiar association
Authors: Borri Juiliana , Silva Junior Hilton Mariano da
Published: February 2022

Introduction: The "Red Ear Syndrome" (RES) is a rare condition (about 100 cases were published in 25 years). It is characterized by episodes of hyperemia of the ear associated with burning pain. Although the association of this syndrome and primary headaches is contemplated in literature, its etiology and treatments are still poorly defined.

The aim of this paper is to report a case of RES related to migraine and possible pathophysiologic mechanisms.

Case Report: A 31-year-old woman presented with stabbing pain and marked erythema and edema of the right ear accompanied by burning and local hyperhidrosis. These attacks lasted 2 hours on average, and either occurred spontaneously or were associated with migraine without aura. The only means of relief during the attacks was cooling the local with ice.

Extensive laboratory-chemical, microbiological, ear-nose-throat, clinical and neurological examinations, magnetic resonance of the brain and cervical spine were unremarkable.

Conclusion: Uncertainty about the etiology of this syndrome is an obstacle to treatment. The frequent relationship between RES and migraine suggests that is necessary to investigate the syndrome in migraineurs. Furthermore, new reports about this disorder are important to increase the knowledge of physicians, to reduce the delay in diagnosis and suffering of patients.
Association of migraine and stress on academic performance (Abstract)
Authors: Bezerra Francimar Nipo
Published: February 2022

Abstract: Thesis (Doctorate in Neurosciences). Postgraduation in Neuropsychiatry and Behavioral Sciences. Federal University of Pernambuco, Recife, Brazil. 2018. 147 f. Supervisor: Prof. Dr. Marcelo Moraes Valença.
A associação da dor cervical crônica e migrânea influência no desempenho do teste de resistência cervical?
Authors: Rodrigues Amanda , Bragato Marcela Mendes , Florencio Lidiane Lima , Bigal Luisa , Bigal Marcelo , Bevilaqua-Grossi Débora
Published: February 2022

Introdução
O relato da dor cervical nos pacientes com migrânea pode contribuir negativamente para o aumento das crises de cefaleia e severidade da alodínia cutânea, com impacto nas atividades de vida diária.
 
Objetivo
Verificar se o desempenho de mulheres com migrânea durante o teste de resistência muscular cervical é afetado pelo diagnóstico clínico de migrânea e/ou dor cervical, pelo relato de dor de cabeça e/ou pescoço ou ambos os componentes.
 
Métodos
100 mulheres estratificadas por diagnóstico (migrânea, dor cervical, ambas e nenhuma) e pela dor autorreferida (com ou sem cefaleia e/ou dor cervical) realizaram o teste de resistência muscular cervical. As participantes foram questionadas se tiveram dor no pescoço e /ou cabeça.  Foi realizado teste T de Welch e o teste McNemar.
 
Resultados
Para o diagnóstico, os dados revelaram que durante o teste de resistência em flexão, os pacientes com migrânea e dor cervical apresentaram menor resistência quando comparados ao controle (p<0,05). Durante a extensão, os grupos de dor cervical com ou sem migrânea tiveram tempo de sustentação menor que o grupo controle (p <0,05). Na estratificação quanto ao relato de dor durante o teste em flexão e extensão, os dados mostraram que aqueles que relataram cefaleia, sustentaram por menos tempo do que aqueles sem cefaleia. Resultados semelhantes foram observados ao comparar aqueles com dor de cabeça e pescoço e sem dor durante o teste (p <0,05).
 
Conclusão
O diagnóstico clínico não foi  único fator decisivo para o desempenho da resistência muscular cervical. A presença do relato de cefaleia associada ou não à dor no pescoço após o teste também limitou a atividade. Portanto, há um componente de sensibilização central que proporciona a alteração no desempenho, porém ainda não é possível determinar se é o fator que atua diretamente no baixo desempenho de migranosas.
Comportamento alimentar e hábitos de vida de universitários com migrânea na pandemia da COVID-19
Authors: Silva Hellen Maria Santos da , Sousa Nathalia Herculano de , Pires Acássia Benjamim Leal , Araujo Ana Patrícia Pascoal Queiroz de , Sousa Maria da Glória Canto de , Santos Alcylene Carla de Jesus dos , Leite Luana de Oliveira
Published: February 2022

Introdução

A migrânea é um tipo de cefaleia de origem multifatorial e é considerada uma doença incapacitante. A pandemia da COVID-19 provocou alterações nos hábitos de vida e padrão alimentar da população, que são importantes gatilhos para as crises migranosas. 

 

Objetivo

Avaliar o impacto das mudanças no estilo de vida e alimentação impostas pela pandemia da COVID-19 quanto à ocorrência de enxaqueca em universitários.

 

Material e Métodos

Estudo transversal, retrospectivo, com abordagem descritiva, realizado com acadêmicos de uma universidade de Salvador, Bahia, no período de 12/2020 a 06/2021. Os universitários foram convocados por meio do aplicativo Whatsapp® e, posteriormente, direcionados via link para acesso ao termo de consentimento livre e esclarecido, que foi preenchido, assim como o questionário, via aplicativo de gerenciamento de pesquisa. Esta pesquisa foi aprovada pelo Comitê de Ética em Pesquisa, sob parecer no 4.351.573. Os dados foram analisados por meio de estatística descritiva. Resultados e Discussões: Amostra constituída por 83 indivíduos, 89,2% mulheres, 45,8% sedentários, 51,8% relataram aumento de peso nos últimos meses e 59% têm dificuldade para conciliar o sono. Antes da pandemia, 7,3% relataram 7-14 dias de enxaqueca por mês e, após, identificou-se aumento para 24,1%. Além disso, 36,1% dos acadêmicos associaram algum alimento às crises de enxaqueca, sendo os gatilhos mais comuns: café (20,5%), chocolate (14,5%), embutidos (12%), bebidas alcóolicas (9,6%) e açúcar (6%). Diante dos resultados, percebe-se que a pandemia implicou no aumento do número de dias com enxaqueca por mês, o que pode estar associado às alterações alimentares, à disfunção do sono potencializada pela crise sanitária, aumento de peso nos últimos meses, assim como devido à prevalência de sedentarismo observada.

 

Conclusões

As mudanças no estilo de vida e no comportamento alimentar ocasionadas pela pandemia da COVID-19 repercutiu no aumento de dias com enxaqueca por mês em universitários.