bluuebunny/crossref_metadata_2025 huggingface dataset:
An Updated Review of Clostridium difficile Treatment in Pediatrics
Authors: Campbell Christopher T. , Poisson Margaret Oates , Hand Elizabeth Oates
Published: April 2019

Clostridium difficile infection (CDI) continues to have clinical and economic impact across all health care settings. Pediatrics accounts for a small percentage of worldwide infection; however, screening and diagnosis are confounded by asymptomatic colonization in young infants. Metronidazole and oral vancomycin have historically been the agents used to manage CDI in both pediatrics and adults. Newer agents and alternative therapies, such as fecal microbiota transplantation, may offer additional benefit. Recent guidelines updates from the Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America separate pediatric and adult recommendations for epidemiology, diagnosis, and treatment. This review will discuss the risk factors, management, prevention, and updated guideline recommendations for CDI in the pediatric population.
Mobilni marketing - savršen komunikacioni kanal zasnovan na interaktivnosti i dozvoli
Authors: Stanić Milenko
Published: April 2019

Mobilni marketing je segment digitalnogmarketinga nastao ekspanzijom mobilnih tehnologija ipodrazumjeva upotrebu mobilnih telefona kao glavnoginteraktivnog komunikacionog kanala ponuđača i potrošača.Ovaj vid marketinga dobija na značaju usljed brze penetracijemobilnih telefona u društvu . Omogućava stalnu komunikaciju sapotrošačima, bez prostornih i vremenskih ograničenja. Brojne sutehnike na kojima je baziran ovaj medij. Cilj ovog rada jeupoznavanje domaće javnosti sa tehnikama mobilnogmarketinga i podsticanje marketinških agencija na većuupotrebu ovog najbrže rastućeg instrumenta savremenihkomunikacija.
Mobilni marketing u službi animiranja publike
Authors: Stanić Milenko , Pirić Damir
Published: April 2019

Savremene marketinške strategije uumjetnosti na prvo mjesto stavljaju umjetnika1 i njegovumjetnički proizvod. Za razliku od standardnog,komercijalnog pristupa, u kojem se proizvod kreira naosnovu potreba potrošača, vrhunsko umjetničko djelo,nastalo iz umjetnikove potrebe, traži svoje «potrošače -publiku». Javnost koja traga za vrhunskim umjetničkimčinom i spremna je da plati za njegovu konzumaciju, kadadođe u kontakt sa tim umjetnilkim činom postaje publikakojoj se svaka kulturna institucija, koja želi da održi nivoadministrativne, umjetničke i tehničke ponude, obraća uzpomoć savremenih alata mobilnog marketinga.
Razvoj i uticaj elektronskog poslovanja na poboljšanje usluga u bankarskom sektoru
Authors: Stanišić Snježana
Published: April 2019

Prilagođavajući se novim izazovima i okolnostimabankarstvo prolazi kroz značajne promjene. Da bi prilagodileponudu proizvoda i usluga kroz nove kanale distribucije bankekoriste nove savremene informacione tehnologije. Proizvodi iusluge banke, su uz pomoć mobilnog bankarstva koji klijentimaomogućava svakodnevnu komunikaciju sa bankom, posebankanal elektronskog bankarstva. Brojne su prednosti koje donosiprimjena informacionih tehnologija u oblasti bankarstva kao štosu smanjenje troškova, povećanje efikasnosti, inovativnost.Nasuprot prednosti javljaju se i nedostaci koji se prvenstvenoogledaju u obezbjeđivanju sigurnosti podataka o klijentima. Ibanke pored klijenata snose rizik mobilnog bankarstva. Zbogzloupotrebe, zaštite na internetu, nedostatka privatnosti, bankemoraju definisati strategiju za rješavanje problema u primjenisavremenih informacionih tehnologija u ovoj oblasti.
Segmentirana zaštita korisničkih podataka u modernim poslovnim sistemima
Authors: Ristić Nenad , Jevremović Aleksandar , Jokić Stevo , Simeunović Nataša
Published: April 2019

U ovom radu analiziraju se postojeća i predlaže se novorešenje problema vezanog za zaštitu korisničkih podatakamodernih poslovnih sistema. Nova metoda se zasnovana naupotrebi složenih i slučajnih dodatnih vrednosti priindividualnom generisanju heš vrednosti za lozinku koju je uneokorisnik kao i upotreba segmentnog hešovanja za šifrovanjelozinke uz standardnu metodu hešovanja SHA512. Lozinka senakon šifrovanja deli u dva dela i delovi se čuvaju u dve zasebnebaze podataka koje se nalaze na različitim platformama.
The Properties Defining Teaching Materials for English Language Courses for IT Students in Serbia
Authors: Dabić Tijana , Adamović Saša
Published: April 2019

The results presented in this paper are a part of amuch more complex mix-method research on the needs of ITstudents in ELT. The paper reports on the properties definingthe teaching materials suitable for IT students in ELT in tertiaryeducation. Since English language is an essential tool for ITstudents to gain professional knowledge and to grow intocompetent individuals in their field, a rather different approachshould be utilised in order to fully assess and question their needsin ELT. The paper discusses on the properties of teachingmaterials for IT students within the framework of Englishlanguage courses for IT students that has been defined by theresearch. The authors want to define teaching materials suitablefor IT students for mainly two reasons: to help the ones withinsufficient language knowledge to reach the satisfying one and toequip the IT students for the target situations in Englishlanguage that they may find themselves in during studies andupon finding a job. The results presented in this paper can bevaluable for all ESP teachers, especially the ones teaching to thestudents at technical faculties.
eHealth adoption and use among healthcare professionals in a tertiary hospital in Sub-Saharan Africa: a Qmethodology study
Authors: Ladan Muhammad Awwal , Wharrad Heather , Windle Richard
Published: April 2019

Background

The aim of the study was to explore the viewpoints of healthcare professionals (HCPs) on the adoption and use of eHealth in clinical practice in sub-Saharan Africa (SSA). Information and communication technologies (ICTs) including eHealth provide HCPs the opportunity to provide quality healthcare to their patients while also improving their own clinical practices. Despite this, previous research has identified these technologies have their associated challenges when adopting them for clinical practice. But more research is needed to identify how these eHealth resources influence clinical practice. In addition, there is still little information about adoption and use of these technologies by HCPs inclinical practice in Sub-Saharan Africa.

Method

An exploratory descriptive design was adopted for this study. Thirty-six (36) HCPs (18 nurses and 18 physicians) working in the clinical area in a tertiary health institution in SSA participated in this study. Using Qmethodology, study participants rank-ordered forty-six statementsin relation to their adoption and use of eHealth within their clinical practice.This was analysed using by-person factor analysis and complemented with audio-taped interviews.

Results

The analysis yielded four factors i.e., distinct viewpoints the HCPs hold about adoption and use of eHealth within their clinical practice. These factors include: “Patient-focused eHealth advocates” who use the eHealth because they are motivated by patients and their families preferences; “Task-focused eHealth advocates” use eHealth because it helps them complete clinical tasks; “Traditionalistic-pragmatists” recognise contributions eHealth makes in clinical practice but separate from their routine clinical activities; and the “Tech-focused eHealth advocates” who use the eHealth because they are motivated by the technology itself.

Conclusion

The study shows the equivocal viewpoints that HCPs have about eHealth within their clinical practice. This, in addition to adding to existing literature, will help policymakers/decision makers to consider HCPs views about these technologies prior to implementing an eHealth resource.
Tree Species Diversity of Ikogosi Warm Spring and Arinta Waterfall Watersheds, Nigeria: Implication for Sustainable Ecotourism
Authors: Olujobi O. J. , Adeleke O. B. , Orimaye J. O.
Published: April 2019

An in-depth knowledge of the richness, diversity and species composition of plant community is vital for providing information for planning and sustainable utilization. This study assesses the diversity of tree species of Ikogosi warm spring and Arinta waterfall watersheds in Ekiti State, Nigeria. Direct observation and vegetation assessment were used for data collection in two hectares (ha) of land divided into four plots of 50 m by 50 m in each of the two study sites (Ikogosi warm spring and Arinta waterfall). Two plots were diagonally selected within each hectare. All living trees of basal diameter ≥10 cm were identified and classified into families. Shannon-Weiner diversity index, species evenness, relative density (RD), relative dominance (RD0) and importance value index (IVI) were used to assess and compare tree species diversity and abundance. Sorenson’s coefficient was used to compare sites for overlapping of similarity. The results revealed that seventy eight (78) species and 25 families were recorded in both watersheds with family Malvaceae having the highest species density (15). Malacantha alnifolia (5) and Voacanga africana (5) were the species most frequently encountered. Species diversity indices revealed vegetation with very high tree species diversity and abundance in the two study sites. Species evenness value revealed even distribution in Arinta waterfall than in Ikogosi warm spring. Diameter and height distribution of trees at the two watersheds indicates a forest structure that is immature and still expanding. Anthocleista vogelii, has the highest value of RD0 (15.63) and IVI (10.6) respectively. The study revealed that some species such as Anthonotha macrophylla, Aningeria robusta, Bridelia atroviridis, among others are threatened and endangered. Consequently, it was recommended that management strategies should be put in place to improve status of the watersheds while conservation efforts should be stepped up for species with rarity index value to prevent them from going into extinction.
Plant Regeneration via Somatic Embryogenesis in Solanum nigrum L. (Black nightshade) (Solanaceae)
Authors: Sharada Durgam , Krishna Porandla Sai , Swamy Nanna Rama
Published: April 2019

Aim: To study the effect of various plant growth regulators (PGRs) for induction of somatic embryogenesis and plantlet formation from cotyledon and leaflet explants in S. nigrum (night shade) an important medicinal plant used in treatment of digestive problems and skin infections.

Place and Duration of Study: Department of Biotechnology, Kakatiya university, Warangal. Telangana, India, 3 years.

Methodology: Cotyledon (0.8 cm2) and leaflet explants (0.8-1.0 cm2) from 3 week and 4 week old were cultured on MS medium supplemented with 30 g/L sucrose along with different concentrations of 0.5 mg/L BAP+NAA (0.5 – 6.0 mg/L) .

Results: Maximum percentage of somatic embryogenesis was observed in cotyledon(89%) and leaf (98%)  explants on MS medium augmented with  0.5mg/L BAP in combination with  2.0 mg/L NAA whereas the highest number of somatic embryos per explant (86 ± 0.19) was formed in leaflet explant.

Conclusion: Somatic embryogenesis was induced from both cotyledon and leaf explants. Since it is threatened and medicinally important species S. nigrum, the present protocol can be used for its conservation and genetic transformation experiments.
Impact of Green Manure and Consortium Biofertilizer on Amylolytic Bacterial Population and Their Activities in Maize Rhizospheric Soil
Authors: Kaur Jaspreet , Gosal S. K. , Walia S. S. , Kaur Jupinder
Published: April 2019

Microbial population and their activities in soil are important measure of soil biological activities as well as its health. The present study was conducted to access the impact of application of green manure and cellulose degrading bacterial consortium on the soil amylolytic bacterial population and amylase activity in rhizosphere of maize crop in field conditions. Soil amylolytic bacteria and amylase activity exhibited significant changes in response to application of consortium biofertilizer. The highest population of amylolytic bacteria was recorded during vegetative stage of maize crop in treatment T8 with 100%N + green manure+ consortium biofertilizer. Amylolytic population was found to be significantly higher in treatments having inorganic N + consortium biofertilizers as compared to control treatment. Soil amylase activity was significantly influenced by organic manure and vegetative growth stage. Highest amylase activity was recorded in treatment T8, whereas minimum activity was recorded in control (inorganic) treatment. Application of consortium biofertilizers significantly increased the amylase activity over treatments having solitary application of inorganic fertilizers. The results suggested that application of consortium biofertilizers on green manure boosted the colonisation and activities of amylolytic bacteria which directly influenced the available carbon pool as well as soil health.
A Review of Methods for Removal of Contaminants in Used Lubricating Oil
Authors: Boadu K. O. , Joel O. F. , Essumang D. K. , Evbuomwan B. O.
Published: April 2019

Management and disposing of used lubricating oil (ULO) poses deleterious effects to air, land and water pollution. These contaminants not only causes environmental problems, they also have bio-accumulation effects on living organisms, reduces the inhabitants lifespan as a result of the diseases spread, poisoning and fouling of catalyst as well as corrode processing equipment. The contaminants removal in used lubricating oil is a major step to avoid pollution as discussed thoroughly by many researchers in literature. In addition, to curbing pollution, another advantage is converting waste to wealth. This review paper presents insight into various methods for removal of contaminants in used lubricating oil. The advantages and drawbacks of each method were earmarked for further study.
Comparison of Phytochemical, Iron Chelating, and Free Radical Scavenging Activity of Fresh Ribes Nigrum (Black Currant) and Nutraceutical C24/7
Authors: Carole Nweze Chibuzor , Olajide Rasaq Nurudeen , Grace Akawu
Published: April 2019

Background: Black currant (Ribes nigrum L. Grossulariceae) promotes good health. A lot of researches have been carried out on common fruits but little attention is given to indigenous fruits such as Ribes nigrum which promotes good health with its high content of phytochemicals that influences its antioxidant activity in neutralizing free radicals as well as its iron chelating property.

Aim of this Study: To compare the phytochemical composition, iron-chelating and the free radical scavenging activity of fresh Ribes nigrum and Nutraceutical C24/7.

Place and Duration of Study: Department of Biochemistry and Molecular Biology, Nasarawa State University, Keffi, Nasarawa State, Nigeria between June 2017 and January 2019.

Methodology: Fleshy parts of fresh Ribes nigrum fruit was homogenized using an electrical blender and was macerated with70% ethanol (Sigma Aldrich, 99.8%) for 72 hours and then filtered. The filtrate was condensed using a rotary evaporator and the extract was stored at 4°C. Preliminary phytochemical screening was carried out on the extract and the nutraceutical C24/7 caplets using standard procedures and the identified phytochemicals: saponins, tannins, alkaloids and steroids were quantitatively estimated. Iron chelating and total antioxidant activity assay was conducted using the DPPH radical scavenging and spectrophotometric methods respectively on the extract and the nutraceutical C24/7. Values were analyzed using One way analysis of Variance (ANOVA).Values of P<0.05 were considered significant.

Results and Conclusion: The findings of this study show that the hydro-ethanol extract of Ribes nigrum contains a large amount of flavonoids, saponins tannins, alkaloids and steroids compounds and exhibits iron chelating and high antioxidant (free radical scavenging) activity compared to nutraceutical-C24/7 caplets.
Spatial Assessment of Land Surface Temperature and Emissivity in the Tropical Littoral City of Port Harcourt, Nigeria
Authors: Nwaerema P. , Vincent Ojeh N. , Amadou C. , Morrison Atuma, I.
Published: April 2019

The study examined Land Surface Temperature (LST) and Land Surface Emissivity (LSE) in a tropical coastal city of Port Harcourt and its environs. Satellite remote sensing of multiple-wavelength origin was employed to derive data from the Landsat Enhance Thematic Mapper (ETM+). Statistical mean and range were used to show pattern of LST and LSE. The study established the relationship and characteristics of land use land cover, built-up area and influence of population on land surfaces. With population of over 3,095,342 persons occupying surface area of approximately 458,28 Km2, rapid vegetal and water body lost have put the city area under pressure of 4.7°C heat bias at the interval of 15 years. From rural fringes to the city center, LST varies with 9.3°C in wet season and 4.8°C in the dry season. During the dry season, LSE is severe in the southern part of the city contributed by water bodies, more vegetal cover and urban pavement materials. Emissivity in the wet season varied with 0.0136 and 0.0006 during the dry season but differs with 0.0165 between the two seasons. One critical finding is that LSE decreases from the rural fringes to the city center and LST increases from the rural fringes to the city center. It is recommended that urban greening at the city center should be practiced and the rural fringes should be explored by decongesting activities at the city center to the outskirts in order to ameliorate the effects of urban heat bias without further delay.
Insecticide Susceptibility Profile of Malaria Vector Populations from the Coastal and Mainland Areas of Akwa Ibom State, Nigeria
Authors: Atting I. A. , Ekpo N. D. , Akpan M. E. , Bassey B. E. , Asuquo M. J. , Usip L. P. E. , Inyama P. U. , Samdi L. M.
Published: April 2019

Development of resistance by different malaria vector populations to insecticides has become a big threat to malaria vector elimination. This study evaluated the susceptibility of Anopheles mosquito populations in Akwa Ibom State, Nigeria to permethrin (0.75%), deltamethrin (0.5%), lambdacyhalothrin (0.5%), alphacypermethrin (0.75%), Dichlorodiphenyltrichloethane (DDT), propoxur, bendiocarb and pirimiphosmethylin in World Health Organization (WHO) test tubes following standard protocols. The mosquitoes were obtained as aquatic forms and reared under laboratory conditions to adults. The adults were subjected to WHO susceptibility bioassays following standard procedures. Malaria vectors across the study sites were resistant to permethrin, deltamethrin, lambdacyhalothrin and alphacypermethrin insecticides. Full susceptibility to propoxur and bendiocarb was recorded across the sites. Full susceptibility to pirimiphosmethyl was recorded in populations from three sites. Nevertheless, population of the malaria vectors collected from Oron was resistant to pirimiphosmethyl. KDT50 and KDT95 estimated for each insecticide using a log-time probit model revealed that knockdown was more rapid for deltamethrin, lambdacyhalothrin, alphacypermethrin, propoxur, bendiocarb and pirimiphosmethyl than for DDT and permethrin  across the study sites. Morphological identification of all the mosquito samples used revealed that they were female Anopheles gambiae s.l. Sustained susceptibility of malaria vectors to pyrethriod is necessary for successful malaria control with insecticide treated nets and Indoor Residual Spraying (IRS). Emergence of focal points with insecticide resistance gives serious concern especially with the scale-up in distribution of pyrethriod treated nets to these areas. This may increase selection pressures due to overexposure. Further study to identify the exact resistance mechanism(s) of malaria vectors from these sites is recommended.
Biochemical Assessment of the Liver in SCD in a Tertiary Hospital in South-South, Nigeria
Authors: Akaba Kingsley , Enang Ofem , Bassey Bassey Okon , Babatope Oluwakorede , Riman Omolabake
Published: April 2019

Background: Sickle cell disease (SCD) is often associated with liver disease. The constant state of haemolysis, multiple blood transfusion, viral hepatitis, hepatic sinusoidal congestion, haemosiderosis and cholestasis, are all conditions which may eventually evolve into liver disease. Sickle cell disease is a heterogeneous group of disorders that is usually associated with an autosomal recessive structural haemoglobin disorder. Biochemical abnormalities have been associated with SCD and it is usually more pronounced in vaso occlusive crises; an acute bone crisis and common painful complication of SCD, than in steady state.

Aim: The aim of the study was to assess some biochemical parameters in relation to SCD patients in our environment with a view to improving the monitoring and management of these patients. 

Methodology: The study was a comparative hospital based research carried out at the University of Calabar Teaching Hospital (UCTH), Calabar, South-South Nigeria. Liver function tests were carried out on 60 SCA both in steady state and in crisis and also on 50 apparently healthy adults.  The data collected were analyzed using statistical data for social sciences (SPSS) Version 22 for windows. Pearson linear correlation and simple inferential statistical methods were employed for data analysis, a P ≤ 0.05 was considered to be statistically significant.

Result: The serum concentrations of AST, ALT, ALP, LDH, Total and conjugated bilirubin were seen to be elevated in VOC compared to in steady state and with the apparently healthy control group. The AST/ALT ratio was also observed to be elevated in VOC as compared with the steady state and the control. Significant product moment correlation was observed in the biochemical parameters both in steady state and in VOC.

Conclusion: The findings of this study revealed marked changes in the biochemical parameters of the liver in VOC than in steady state. It will be recommended that routine evaluation and proper interpretation of liver enzymes is paramount in early detection of liver pathology in SCD.
Impacts of Meteorological Attributes on Agronomic Characteristics of Sunflower Cultivated in the Cerrado
Authors: Faria Dayana Aparecida de , Pallaoro Dryelle Sifuentes , Ferrari Murilo , Borba Filho Aloisio Brigido , De Abreu Joadil Gonçalves , Camili Elisangela Clarete , Avelino Anne Caroline Dallabrida , Sales Kyron Cabral , Júnior José Holanda Campelo , Carvalho Claudio Guilherme Portela de
Published: April 2019

The sunflower has adaptation for cultivation in Brazilian conditions and the main product is the oil extracted from the seeds. This study aimed to verify the impacts of meteorological attributes on agronomic characteristics of sunflower genotypes cultivated as a second crop, in Mato Grosso, Brazil. The experimental design was randomized complete block design (RCBD), cultivating the two sunflower genotypes, M734 and Hélio, in three years (2009, 2011, 2012) with four replications. The agronomic characteristics evaluated were: plant height, capitulum diameter, weight of a thousand achenes, yield of achenes, oil content and oil yield. Then, water deficit and the maximum crop yield are estimated for correlation analysis between meteorological attributes and agronomic characteristics. In both genotypes studied there was a very strong correlation between plant height with evapotranspiration (r=0.99*) and very strong negative correlation (r=-0.99*) with water deficit. For mass of a thousand achenes, there was a very strong negative correlation with the maximum (r=-0.98*) and minimum (r=-0.96*) temperatures, and with evapotranspiration (r=-0.98*) in the Helio 358. In addition, effect of the water deficit on the oil yield (r=-0.98*) was verified for the same genotype. Very strong negative correlation was found between maximum temperature and oil content (r=-0.96*) in genotype M734. In sunflower cultivation in Mato Grosso, Brazil, water deficit reduces plant height, capitulum diameter and oil yield. The oil content of the achenes reduces when the maximum temperature increases, during the cultivation. For those reasons, the use of sunflower genotypes with shorter cycles and the earlier sowing could benefit the crop developing, by suiting the management, to avoid unfavorable climatic conditions that can cause reduction in production parameters.
On the Application of Coefficient of Anisotropy as an Index of Groundwater Potential in a Typical Basement Complex of Ado Ekiti, Southwest, Nigeria
Authors: Olayinka A. I. , Oyedele E. A. A.
Published: April 2019

This paper examines the application of the Dar Zarrouk parameter, the Coefficient of Anisotropy to Groundwater Potential Evaluation in a typical Basement Complex Terrain of Ado-Ekiti Southwest, Nigeria. A regional Geoelectric Depth sounding was carried out across the metropolis using the Schlumberger electrode array. Resistivity-depth image in terms of layer thickness and resistivity was used to compute the Coefficients of Anisotropy for the VES locations occupied. Thematic maps of the geoelectric parameters were generated using the Concept of Geographical Information System (GIS). Comparative Map Analysis revealed that a range of 1.3 to 1.6 Anisotropy values was observed across the zones characterized by thick overburden, Weathered Basement Thickness in excess of 25m, low weathered basement resistivity, fractured bedrock and basement depressions in the study area. Anisotropy values ranging from 1.8 to 2.8 were observed across the basement ridges and zones characterized by thin overburden, Weathered Basement Thickness of generally less than 15m and Weathered Basement resistivity greater than 1500 Ω-m with least groundwater potential. The regions of Anisotropy values ranging from 1.3 to 1.6 are demarcated as high groundwater potential zones. Areas characterized by higher Anisotropy values can be associated with low porosity and permeability with less hydro geological appeal.
PENGARUH PERCEIVED SERVICE QUALITY TERHADAP REPURCHASE DAN CUSTOMER SATISFACTION SEBAGAI VARIABEL INTERVENING PADA FAST FOOD RESTAURANT DI SURABAYA
Authors: Saintz Jocellynne
Published: April 2019

The purpose of this research aims to analyze the effects of Perceived Service Quality towards Repurchase with Customer Satisfaction as an intervening variabel  inFast food restaurant. This research was conducted by distributing questionnaires to 100 respondents who were customers of Fast food restaurants who had made transactions in the last six month. This research use the Perceived service quality (X1) variable with the indicators Reliability, Responsiveness, Assurance, Empathy, Tangible, Customer satisfaction variable (Y1) with the indicators Fulfillment, Pleasure, Ambivalance, Repurchase variable (Z1) with the indicators Interest, Pleasure-based value, Sign value, Risk Pribability, dan Risk. The results show: (1) Perceived service quality influence significantly effect customer satisfaction; (2) Perceived service quality affect significantly effect repurchase; (3) customer satisfaction has a significant impact on repurchase
ANALISIS PENGARUH FASHION INVOLVEMENT TERHADAP IMPULSE BUYING MELALUI HEDONIC VALUE DI H&M STORE PAKUWON MALL SURABAYA
Authors: Natalie A. Angela , Japarianto Edwin
Published: April 2019

Penelitian ini bertujuan untuk mengetahui pengaruh dari Fashion Involvement terhadap Impulse Buying melalui Hedonic Value yang dilakukan oleh konsumen fashion di H & M Store Pakuwon Mall Surabaya. Penelitian ini dilaksanakan dengan menyebarkan kuesioner kepada 100 responden pelanggan H & M di Pakuwon Mall Surabaya.Teknik analisa yang digunakan adalah teknik analisis kuantitatif dengan metode path analisis. Hasil penelitian ini menunjukan bahwa fashion involvement berpengaruh secara positif dan signifikan terhadap hedonic value, fashion involvement berpengaruh secara positif dan signifikan terhadap impulse buying, dan hedonic value berpengaruh secara berpengaruh secara positif dan signifikan terhadap impulse buying, serta menunjukan bahwa hedonic value sebagai variable intervening tidak berhasil memediasi hubungan antara fashion involvement dan impulse buying.
Regulation of the unfolded protein response in yeast by oxidative stress
Authors: Guerra‐Moreno Angel , Ang Jessie , Welsch Hendrik , Jochem Marco , Hanna John
Published: April 2019

In the unfolded protein response (UPR), Ire1 activates Hac1 to coordinate the transcription of hundreds of genes to mitigate ER stress. Recent work in Caenorhabditis elegans suggests that oxidative stress inhibits this canonical Ire1 signalling pathway, activating instead an antioxidant stress response. We sought to determine whether this novel mode of UPR function also existed in yeast, where Ire1 has been best characterized. We show that the yeast UPR is also subject to inhibition by oxidative stress. Inhibition is mediated by a single evolutionarily conserved cysteine, and affects both luminal and membrane pathways of Ire1 activation. In yeast, Ire1 appears dispensable for resistance to oxidative stress and, therefore, the physiological significance of this pathway remains to be demonstrated.
Non‐Oxidative Enzymatic (De)Carboxylation of (Hetero)Aromatics and Acrylic Acid Derivatives
Authors: Payer Stefan E. , Faber Kurt , Glueck Silvia M.
Published: April 2019

The utilization of carbon dioxide as a C1‐building block for the production of valuable chemicals has recently attracted much interest. Whereas chemical CO2 fixation is dominated by C−O and C−N bond forming reactions, the development of novel concepts for the carboxylation of C‐nucleophiles, which leads to the formation of carboxylic acids, is highly desired. Beside transition metal catalysis, biocatalysis has emerged as an attractive method for the highly regioselective (de)carboxylation of electron‐rich (hetero)aromatics, which has been recently further expanded to include conjugated α,β‐unsaturated (acrylic) acid derivatives. Depending on the type of substrate, different classes of enzymes have been explored for (i) the ortho‐carboxylation of phenols catalyzed by metal‐dependent ortho‐benzoic acid decarboxylases and (ii) the side‐chain carboxylation of para‐hydroxystyrenes mediated by metal‐independent phenolic acid decarboxylases. Just recently, the portfolio of bio‐carboxylation reactions was complemented by (iii) the para‐carboxylation of phenols and the decarboxylation of electron‐rich heterocyclic and acrylic acid derivatives mediated by prenylated FMN‐dependent decarboxylases, which is the main focus of this review. Bio(de)carboxylation processes proceed under physiological reaction conditions employing bicarbonate or (pressurized) CO2 when running in the energetically uphill carboxylation direction. Aiming to facilitate the application of these enzymes in preparative‐scale biotransformations, their catalytic mechanism and substrate scope are analyzed in this review.

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Effect of pore geometry on nanoconfined water transport behavior
Authors: Sun Zheng , Wu Keliu , Shi Juntai , Zhang Tao , Feng Dong , Wang Suran , Liu Wenyuan , Mao Shaowen , Li Xiangfang
Published: April 2019

Different pore shapes correspond to different interaction strengths between pore surface and molecules, which will result in discrepancy of nanoconfined water transport capacity. In this article, complex nanoscale pore shapes are represented by ellipses, which possess an excellent shape‐variation physical property, that is, ellipses can gradually transition from circles to slit‐like cross‐sections by manipulating aspect ratio from 1 to maxima. Moreover, capturing water slip phenomenon and spatially variation of water viscosity, an analytical model for water transport capacity through elliptical nanopores is developed. Results show that (a) water slip effect plays a limited positive role at hydrophilic environment and a strong positive role at hydrophobic environment; (b) nanopores with more flat geometry feature will possess smaller enhance factor at hydrophilic environment; (c) spatially viscosity distribution is a negative factor when contact angle is lower than about 130° and turns to a positive factor when contact angle is higher than about 130°.
Water influences how seed production responds to conspecific and heterospecific pollen
Authors: Recart Wilnelia , Ottoson Brittany , Campbell Diane R.
Published: April 2019

Premise

Outcrossing species depend on pollen from conspecific individuals that may not be exposed to the same abiotic conditions as maternal plants. Additionally, many flowers receive heterospecific pollen, which can also influence seed production. Studies aimed to understand how abiotic conditions influence seed production tend to focus on maternal conditions and leave unexplored the effect of abiotic conditions experienced by pollen donors. We tested how water availability to pollen donors, both conspecific and heterospecific, influenced the seed production of recipient plants exposed to different water availability regimes.

Methods

In a greenhouse setting we manipulated the water availability (low‐ or high‐water treatment) to potted recipient plants (Phacelia parryi), to conspecific pollen donors, and to heterospecific pollen donors (Brassica nigra). We hand pollinated recipient plants with different pollen mixes that represented all combinations of conspecific pollen mixed with heterospecific pollen. From these hand pollinations we determined the amount of pollen that was transferred, pollen volume, pollen shape, and seed production.

Results

Higher water availability to conspecific pollen donors led to higher seed production. Under low water availability to heterospecific pollen donors, seed production was unaffected by recipient or conspecific pollen donor treatment. Under high water availability to heterospecific pollen donors, seed production was highest when conspecific pollen donors and pollen recipients also received the high‐water treatment.

Conclusions

Environmental conditions of pollen donors can influence the seed production of maternal plants. These results illustrate potential impacts of environmental heterogeneity on post‐pollination events that lead to seed production and thus impact a pollinator's contribution to plant fitness.
Workforce Support for Urban After‐School Programs: Turning Obstacles into Opportunities
Authors: Frazier Stacy L. , Chou Tommy , Ouellette Rachel R. , Helseth Sarah A. , Kashem Erin R. , Cromer Kelly D.
Published: April 2019

Highlights

Resource and workforce challenges impede adoption of evidence‐based practice in after‐school programs.

Academic–community partnerships inform recommendations that align with individual program goals.

We describe a three‐tiered approach to workforce support with online, workshop, and on‐site components.

Content prioritizes mental health kernels: emotion regulation, communication, and problem‐solving.

Support leverages teachable moments inherent to recreation and harnesses staff talent and expertise.
Variations in epiphyseal fusion and persistence of the epiphyseal line in the appendicular skeleton of two identified modern (19th–20th c.) adult Portuguese and Italian samples
Authors: Belcastro Maria Giovanna , Pietrobelli Annalisa , Rastelli Elisa , Iannuzzi Vincenzo , Toselli Stefania , Mariotti Valentina
Published: April 2019

Objectives

The aim of this work is to study age, sex, and population variations in epiphyseal fusion and persistence of the epiphyseal line in the appendicular skeleton of two identified modern (19th–20th c.) adult skeletal samples, using a specifically designed macroscopic scoring method. The use of epiphyseal closure and persistence of the epiphyseal line as an adult‐age marker is also discussed.

Materials and methods

This study examined 981 adult skeletons of both sexes from two identified modern (20th c.) skeletal samples from the Sassari Collection (Museum of Anthropology, University of Bologna, Italy) and the Colecção de Esqueletos Identificados (Museum of Anthropology, University of Coimbra, Portugal). Our scoring method considers a five‐degree scale, from nonfusion (Degree 0) to complete fusion (Degree 4). In addition, the persistence of the epiphyseal line, a feature that is not commonly collected during routine anthropological analyses, is taken into account here as Degree 3.

Results

Intra‐ and interobserver errors of 1.2% and 5.2%, respectively, were found, suggesting a good reproducibility of this scoring method. Some sites show variable degrees of epiphyseal fusion still in adult skeletons (e.g., secondary center of ossification of the clavicle, iliac crest, ischial tuberosity, distal epiphysis of the radius and ulna).

Conclusions

Population differences have been observed, showing a delay in the complete epiphyseal closure for the Sassari sample compared to the Coimbra sample. Degree 3 seems to be a good adult‐age indicator for individuals less than 35‐year‐old.
Large Second Harmonic Generation (SHG) Effect and High Laser‐Induced Damage Threshold (LIDT) Observed Coexisting in Gallium Selenide
Authors: Guo Sheng‐Ping , Cheng Xiyue , Sun Zong‐Dong , Chi Yang , Liu Bin‐Wen , Jiang Xiao‐Ming , Li Shu‐Fang , Xue Huai‐Guo , Deng Shuiquan , Duppel Viola , Köhler Jürgen , Guo Guo‐Cong
Published: April 2019

A big challenge for nonlinear optical (NLO) materials is the application in high power lasers, which needs the simultaneous occurrence of large second harmonic generation (SHG) and high laser induced damage threshold (LIDT). Herein we report the preparation of a new Ga2Se3 phase, which shows the SHG intensities of around 2.3 times and the LIDT of around 16.7 times those of AgGaS2 (AGS), respectively. In addition, its IR transparent window ca. 0.59–25 μm is also significantly wider than that of AGS (ca. 0.48–≈11.4 μm). The occurrence of the strong SHG responses and good phase‐matching indicate that the structure of the new Ga2Se3 phase can only be non‐centrosymmetric and have a lower symmetry than the cubic γ‐phase. The observed excellent SHG and phase‐matching properties are consistent with our diffraction experiments and can be well explained by using the orthorhombic models obtained through our high throughput simulations.
A facile route to prepare homogeneous silicone resin doped with titanium
Authors: Chen Jianjun , Fu Zien , Huang Hengchao , Chen Zhonghua , Zeng Xingrong
Published: April 2019

A facile route was introduced to prepare homogeneous silicone resin doped with titanium hybrid with high refractive index (RI). Specifically, the hybrids were obtained from the transesterification of hydroxyl‐phenyl‐vinyl silicone resin and titanium isopropoxide under anhydrous conditions. The structures of hybrid silicone and their corresponding intermediates (hydroxyl‐phenyl‐vinyl silicone) were characterized by nuclear magnetic resonance spectroscopy (1H NMR, 29Si NMR) as well as Fourier transform infrared spectroscopy (FTIR). The hybrids had a transmittance of more than 88% ranging from 450 nm to 800 nm, a high RI of 1.585, and a lower water vapor permeability of 3.58 g /m2.24h. Results from FTIR showed intensity of Ti‐O‐Si bond in hybrid decrease with extended the storage time, but the properties of cured hybrids including optical, mechanical, and gas permeability were not influenced. Compared to chips encapsulated with pure silicone, the luminous efficiency of the chips encapsulated with hybrids was improved from 138.6 lm/W to 156.4 lm/W. The thermal shock and hygrothermal aging test also demonstrated the hybrids had a wide range application in light‐emitting diode (LED) packaging. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019, 136, 47834.
Projection of fossil fuel demands in Vietnam to 2050 and climate change implications
Authors: Tran Quang Minh
Published: April 2019

Over the past decade, Vietnam has emerged as one of the world's fastest growing economies. Fossil fuel use, which is a dominant energy source and vital for economic growth, have been increasing considerably. Undoubtedly, the projection of fossil fuel demand is essential for a better understanding of energy needs, fuel mix, and Vietnam's strategic development. This paper provides an outlook for coal, oil, and gas demand in Vietnam to 2050. The projection is based on the calibrated results from a hybrid model (that combines a GTAP‐ R version for resources, and a micro simulation approach) and an energy database. Under the baseline scenario (business as usual), from 2018 to 2050, the demand for coal, oil products, and gas are expected to increase by a factor of 2.47‐fold, 2.14‐fold, and 1.67‐fold, respectively. Emissions are also projected to increase. Because fossil fuels are the dominant source of carbon emissions in Vietnam, it follows, going forward, that an effective fuel‐mix strategy that encourages the development of renewables and energy efficiency is essential.
A non randomized mentalization intervention for parents of children with autism
Authors: Enav Yael , Erhard‐Weiss Dana , Kopelman Mirit , Samson Andrea C. , Mehta Smriti , Gross James J. , Hardan Antonio Y.
Published: April 2019

Parents of children diagnosed with autism spectrum disorder (ASD) report higher levels of stress and other negative affective states than parents of typically developing children. One important resource in managing these heightened levels of negative affect is emotion regulation, which in turn depends upon the ability to recognize and understand one's own and others' mental states (referred to as mentalization or reflective functioning). In this study, parents of children with ASD either participated in a mentalization‐based group intervention (N = 36) or a delayed treatment (N = 28). Compared to delayed treatment participants, parents in the mentalization‐based group had increases in reflective functioning and in the belief that emotions can change. Moreover, they reported decreased behavioral and emotional symptoms in their children, and greater parental self‐efficacy. These preliminary findings support previous studies, which have shown that mentalization‐based interventions for parents lead to positive outcomes, and suggest that these findings may apply to a diverse population of parents such as those of children with broader autism phenotype or children with different neurological disorders. Further studies to evaluate the effects of the intervention are recommended. Autism Res 2019, 12: 1077–1086. © 2019 International Society for Autism Research, Wiley Periodicals, Inc.

Lay Summary

In this study, parents of children with ASD participated in a group intervention designed to increase their awareness of mental states (their own and their children's) and to enhance their emotion regulation. Compared to delayed treatment parents, those in the intervention group showed increased awareness of developmental states, and reported increased belief that emotions can change and decreased levels of behavioral and emotional symptoms in their children.
Colonic dilation and altered ex vivo gastrointestinal motility in the neuroligin‐3 knockout mouse
Authors: Leembruggen Anita J. L. , Balasuriya Gayathri K. , Zhang Jinghong , Schokman Shana , Swiderski Kristy , Bornstein Joel C. , Nithianantharajah Jess , Hill‐Yardin Elisa L.
Published: April 2019

Gastrointestinal (GI) dysfunction is commonly reported by people diagnosed with autism spectrum disorder (ASD; autism) but the cause is unknown. Mutations in genes encoding synaptic proteins including Neuroligin‐3 are associated with autism. Mice lacking Neuroligin‐3 (Nlgn3−/−) have altered brain function, but whether the enteric nervous system (ENS) is altered remains unknown. We assessed for changes in GI structure and function in Nlgn3−/− mice. We found no significant morphological differences in villus height or crypt depth in the jejunum or colon between wildtype (WT) and Nlgn3−/− mice. To determine whether deletion of Nlgn3 affects enteric neurons, we stained for neural markers in the myenteric plexus. Nlgn3−/− mice had similar numbers of neurons expressing the pan‐neuronal marker Hu in the jejunum, proximal mid, and distal colon regions. We also found no differences in the number of neuronal nitric oxide synthase (nNOS+) or calretinin (CalR+) motor neurons and interneurons between WT and Nlgn3−/− mice. We used ex vivo video imaging analysis to assess colonic motility under baseline conditions and observed faster colonic migrating motor complexes (CMMCs) and an increased colonic diameter in Nlgn3−/− mice, although CMMC frequency was unchanged. At baseline, CMMCs were faster in Nlgn3−/− mice compared to WT. Although the numbers of neuronal subsets are conserved in Nlgn3−/− mice, these findings suggest that Neuroligin‐3 modulates inhibitory neural pathways in the ENS and may contribute to mechanisms underlying GI disorders in autism. Autism Res 2020, 13: 691–701. © 2019 The Authors. Autism Research published by International Society for Autism Research published byWiley Periodicals, Inc.

Lay Summary

People with autism commonly experience gut problems. Many gene mutations associated with autism affect neuronal activity. We studied mice in which the autism‐associated Neuroligin‐3 gene is deleted to determine whether this impacts gut neuronal numbers or motility. We found that although mutant mice had similar gut structure and numbers of neurons in all gut regions examined, they had distended colons and faster colonic muscle contractions. Further work is needed to understand how Neuroligin‐3 affects neuron connectivity in the gastrointestinal tract.
Three to four years outcomes of the absorb bioresorbable vascular scaffold versus second‐generation drug‐eluting stent: A meta‐analysis
Authors: Goel Sunny , Pasam Ravi Teja , Chava Srilekha , Sharma Abhishek , Malik Bilal Ahmad , Ayzenberg Sergey , Frankel Robert , Shani Jacob , Gidwani Umesh
Published: April 2019

Objective

This meta‐analysis sought to evaluate the outcomes of absorb bioresorbable vascular scaffolds (BVS) compared with second‐generation drug‐eluting stents (DES) after 3 years, the approximate time of complete polymer bioresorption.

Background

BVS were found to be inferior to second‐generation DES in early and mid‐term outcomes with a higher rate of target vessel myocardial infarction (TV‐MI) and device thrombosis (DT). Improper implantation techniques and incomplete bioresorption of the poly‐l‐lactide (PLLA) polymer were sighted as possible reasons.

Methods

We conducted an electronic database search for all randomized control trials that compared absorb BVS to second‐generation DES and reported outcomes of interest after 3 years of absorb BVS implantation. Assuming interstudy heterogeneity, a random‐effects analysis was conducted with odds ratio as the effect size of choice to compare the event rates between the two groups.

Results

A total of four studies (n = 3,245, BVS = 2075, DES = 1,170) were included in the final analysis. Pooled analysis revealed that there was no difference between absorb BVS and second‐generation DES with respect to target lesion failure (TLF) (OR = 1.23, 95% CI = 0.73–2.07, p = 0.44), TV‐MI (OR = 1.03, 95% CI = 0.42–2.53, p = 0.95), target lesion revascularization (TLR) (OR = 1.61, 95% CI = 0.77–3.33, p = 0.20) and definite/probable DT (OR = 0.71, 95% CI = 0.10–5.07, p = 0.74). Also, there was no difference in cardiac mortality (OR = 0.66, 95% CI = 0.22–1.94, p = 0.45).

Conclusions

Between 3 and 4 years of follow‐up, patients receiving absorb BVS did not have significantly different outcomes, in terms of TLF, TV‐MI, TLR, DT, and cardiac mortality, compared to DES.