bluuebunny/crossref_metadata_2025 huggingface dataset:
Preparation of nano‐zinc oxide/EPDM composites with both good thermal conductivity and mechanical properties
Authors: Wang Zhenhua , Lu Yonglai , Liu Jun , Dang Zhimin , Zhang Liqun , Wang Weimin
Published: October 2010

In this article, nano‐zinc oxide (ZnO) filled ethylene propylene diene monomer (EPDM) composites are prepared, and the mechanical (static and dynamic) properties and thermal conductivity are investigated respectively, which are further compared with the traditional reinforcing fillers, such as carbon black and nano‐silica. Furthermore, influence of in‐situ modification (mixing operation assisted by silane at high temperature for a certain time) with the silane‐coupling agent Bis‐(3‐thiethoxy silylpropyl)‐tetrasufide (Si69) on the nano‐ZnO filled composites is as well investigated. The results indicate that this novel reinforcing filler nano‐ZnO can not only perform well in reinforcing EPDM but can also improve the thermal conductivity significantly. In‐situ modification with Si69 can enhance the interfacial interaction between nano‐ZnO particles and rubber matrix remarkably, and therefore contribute to the better dispersion of filler. As a result, the mechanical properties and the dynamic heat build‐up of the nano‐ZnO filled composites are improved obviously by in‐situ modification, without influencing the thermal conductivity. In comparison with traditioanl reinforcing fillers, in‐situ modified nano‐ZnO filled composites exhibit the excellent performance in both mechanical (static and dynamic) properties and better thermal conductivity. In general, our work indicates that nano‐ZnO, as the novel thermal conductive reinforcing filler, is suitable to prepare elastomer products serving in dynamic conditions, with the longer expected service life. © 2010 Wiley Periodicals, Inc. J Appl Polym Sci, 2011
Peas starch‐based film coatings for site‐specific drug delivery to the colon
Authors: Karrout Y. , Neut C. , Wils D. , Siepmann F. , Deremaux L. , Flament M. P. , Dubreuil L. , Desreumaux P. , Siepmann J.
Published: October 2010

Peas starch : ethylcellulose‐based film coatings are proposed allowing for site‐specific drug delivery to the colon of inflammatory bowel disease patients. The film coatings are poorly permeable for 5‐aminosalicylic acid in media simulating the contents of the stomach and small intestine. Thus, they can minimize premature drug release in the upper gastrointestinal tract and subsequent absorption into the blood stream. However, once the colon is reached, drug release sets on and is time controlled. This can be attributed to the partial degradation of the peas starch by enzymes secreted by bacteria, which are preferentially present in the colon. Thus, the drug is released at the site of action, which is likely to minimize undesired side effects in the healthy part of the human body and to optimize the therapeutic efficacy of the treatment. A blend ratio of 1 : 4 peas starch : ethylcellulose and a coating level of 15% (w/w) seem to be optimal for pellet coating. Importantly, the polymeric films can be expected to withstand the mechanical stress encountered in vivo because of the motility of the stomach and small intestine. Furthermore, the systems are long‐term stable: drug release from coated pellets remains unaltered during 1‐year open storage. © 2010 Wiley Periodicals, Inc. J Appl Polym Sci, 2011
Immunonutrition in gastrointestinal surgery
Authors: Cerantola Y , Hübner M , Grass F , Demartines N , Schäfer M
Published: October 2010

Background

Patients undergoing major gastrointestinal surgery are at increased risk of developing complications. The use of immunonutrition (IN) in such patients is not widespread because the available data are heterogeneous, and some show contradictory results with regard to complications, mortality and length of hospital stay.

Methods

Randomized controlled trials (RCTs) published between January 1985 and September 2009 that assessed the clinical impact of perioperative enteral IN in major gastrointestinal elective surgery were included in a meta-analysis.

Results

Twenty-one RCTs enrolling a total of 2730 patients were included in the meta-analysis. Twelve were considered as high-quality studies. The included studies showed significant heterogeneity with respect to patients, control groups, timing and duration of IN, which limited group analysis. IN significantly reduced overall complications when used before surgery (odds ratio (OR) 0·48, 95 per cent confidence interval (c.i.) 0·34 to 0·69), both before and after operation (OR 0·39, 0·28 to 0·54) or after surgery (OR 0·46, 0·25 to 0·84). For these three timings of IN administration, ORs of postoperative infection were 0·36 (0·24 to 0·56), 0·41 (0·28 to 0·58) and 0·53 (0·40 to 0·71) respectively. Use of IN led to a shorter hospital stay: mean difference − 2·12 (95 per cent c.i. − 2·97 to − 1·26) days. Beneficial effects of IN were confirmed when low-quality trials were excluded. Perioperative IN had no influence on mortality (OR 0·90, 0·46 to 1·76).

Conclusion

Perioperative enteral IN decreases morbidity and hospital stay but not mortality after major gastrointestinal surgery; its routine use can be recommended.
Physiological assessment of renal artery stenosis: Comparisons of resting with hyperemic renal pressure measurements
Authors: Kapoor Nikhil , Fahsah Ibrahim , Karim Rehan , Jevans Anthony J. , Leesar Massoud A.
Published: October 2010

Objectives: We compared resting and hyperemic pressure gradients induced by intrarenal papaverine for the assessment of renal artery stenosis (RAS). We also investigated the incidence of the QT interval prolongation and ventricular arrhythmias. Background: In the coronary circulation, maximal hyperemia is essential in determining the significance of a stenosis. In the renal circulation, the role of maximal hyperemia for the assessment of RAS has not been established. Methods: In 55 patients with RAS (67 RAS), resting Pd/Pa ratio (the ratio between distal renal pressure to the aortic pressure), renal fractional flow reserve (FFR), and resting and hyperemic systolic gradients (RSG and HSG, respectively) were measured with a pressure guidewire. In a subset of 16 patients, renal vein renin activity (RVRA) was measured. Results: HSG was significantly greater than RSG (20 ± 14 mm Hg vs. 9.0 ± 13 mm Hg, respectively; P < 0.001). Renal FFR was significantly lower than baseline Pd/Pa ratio (0.91 ± 0.06 vs. 0.94 ± 0.06 vs. respectively; P < 0.001). RVRA increased from 50 ± 66% at rest to 122 ± 112% at hyperemia, P < 0.01. At HSG of 21 mm Hg or renal FFR of 0.90, RVRA increased markedly (120%), but RVRA increased modestly (18%) when RSG was 16 mm Hg or resting Pd/Pa ratio was 0.93. The corrected QT intervals at baseline vs. hyperemia were not significantly different (433 ± 26 vs. 436 ± 25 msec, respectively; P = NS); no episodes of ventricular arrhythmias were noted. Conclusions: Renin production, an index of renal ischemia, was markedly greater at hyperemia than at rest, suggesting that RAS, with either an HSG of 21 mm Hg or a renal FFR of 0.90, can be considered a hemodynamically significant stenosis. Intrarenal papaverine neither prolonged the QT interval nor induced ventricular arrhythmias and the safety of which will need to be corroborated in a large study. © 2010 Wiley‐Liss, Inc.
Figulla PFO occluder versus Amplatzer PFO occluder for percutaneous closure of patent foramen ovale
Authors: Saguner Ardan M. , Wahl Andreas , Praz Fabien , de Marchi Stefano F. , Mattle Heinrich P. , Cook Stéphane , Windecker Stephan , Meier Bernhard
Published: October 2010

Background: Percutaneous closure of patent foramen ovale (PFO) has been shown safe and feasible using several devices. The Occlutech Figulla single layer PFO Occluder (FPO) constitutes an alternative to the Amplatzer PFO Occluder (APFO). Objectives: We report our experience with both devices in a single‐center case–control study. Methods: Twenty patients undergoing percutaneous PFO closure using an FPO for secondary prevention of paradoxical embolism or diving were blindly matched with 20 patients receiving an APFO during the same time period. Contrast transesophageal echocardiography (TEE) was performed 6 months after device implantation to assess for residual shunting and device‐associated thrombus. Results: Patient baseline characteristics were well matched by study design. Procedural success was 95% with FPO vs. 100% for APFO (P = 1.0), with 3 (15%) peri‐procedural complications with FPO vs. none with APFO (P = 0.24). These comprised one asymptomatic device embolization in the descending aorta with percutaneous retrieval, one transient ischemic attacks, and one suspected device endocarditis. Contrast TEE at 6 months showed significantly more residual shunts in the FPO‐group (39% vs. 0%; P = 0.01). Two FPO patients with a moderate residual shunt underwent implantation of a second device (APFO 25 mm) vs. none in the APFO group (P = 0.48). No thrombi were observed in either group. During 1.7 ± 0.7 years of follow‐up, no death or recurrent embolic event occurred. Conclusions: According to this single‐center case–control study, PFO closure with the FPO appears less efficacious than with the APFO. © 2010 Wiley‐Liss, Inc.
Overview and Industrial Assessment of Synthesis Strategies towards Zeolites with Mesopores
Authors: Chal Robin , Gérardin Corine , Bulut Metin , van Donk Sander
Published: October 2010

With the necessity for the refining industry to treat heavier feedstocks, there is a clear demand for improved zeolite materials displaying better accessible surface areas and higher pore volumes in order to capitalize on their effectiveness. To this end, over the last decade, there has been an intensification of research on the exploration of new routes to synthesize zeolite materials combining micropores with mesopores. Different synthesis strategies are used for their preparation (i.e., by structure breaking or so‐called ‘destructive’ pathways, or structure building or so‐called ‘constructive’ synthesis pathways). This Review discusses the variety of current synthesis strategies, while emphasizing the strengths and weaknesses of the different routes regarding material characteristics; health, safety, and environment aspects; and synthesis costs.
Catalytic Transformation of Ethanol with Silicalite‐1: Influence of Pretreatments and Conditions on Activity and Selectivity
Authors: Della Pina Cristina , Falletta Ermelinda , Gervasini Antonella , Teles J. Henrique , Rossi Michele
Published: October 2010

Silicalite‐1 undergoes a reversible cycle of acid activation and base deactivation when employed as a catalyst for the vapor‐phase dehydration of ethanol at 230–300 °C. In particular, a pretreatment with aqueous HCl strongly promotes the production of diethyl ether at lower temperatures (230–270 °C) or ethene at higher temperature (300 °C). The activated catalyst becomes completely inactive upon addition of aqueous potassium acetate, whereas the catalytic effect is restored by repeating the acid treatment. Moreover, the reversible exchange of H+ with K+, introduced as KCl salt, in HCl‐activated silicalite causes the suppression of the catalytic activity. Several analytical techniques, as the acidic sites characterization, surface area‐porosity determination and electron microscopy images were unable to display surface modifications responsible for the important catalytic effect induced by HCl treatment. It is proposed that HCl treatment allows the formation of protonated and neutral chemical groups, such as SiOSi surface bridges, behaving as active sites for ethanol dehydration. On the surface of the catalyst, K+ competes with H+ and strongly inhibits alcohol dehydration.
Integrating Replication‐Based Selection Strategies in Dynamic Covalent Systems
Authors: del Amo Vicente , Philp Douglas
Published: October 2010

In the past 15 years, the chemistry of reversible covalent bond formation (dynamic covalent chemistry (DCC)) has been exploited to engineer networks of interconverting compounds known as dynamic combinatorial libraries (DCLs). Classically, the distribution of library components is governed by their relative free energies, and so, processes that manipulate the free energy landscape of the DCL can influence the distribution of library members. Within the same time frame, the design and implementation of molecules capable of copying themselves—so‐called replicators—has emerged from the field of template‐directed synthesis. Harnessing the nonlinear kinetics inherent in replicator behavior offers an attractive strategy for amplification of a target structure within a DCL and, hence, engendering high levels of selectivity within that library. The instructional nature of replicating templates also renders the combination of replication and DCC a potential vehicle for developing complex reaction networks; a prerequisite for the development of the emerging field of systems chemistry. This Concept article explores the role of kinetically and thermodynamically controlled processes within different DCC frameworks. The effects of embedding a replicating system within these DCC frameworks is explored and the consequences of the different topologies of the reaction network for amplification and selectivity within DCLs is highlighted.
Sb2S3 with Various Nanostructures: Controllable Synthesis, Formation Mechanism, and Electrochemical Performance toward Lithium Storage
Authors: Ma Jianmin , Duan Xiaochuan , Lian Jiabiao , Kim Tongil , Peng Peng , Liu Xiaodi , Liu Zhifang , Li Haobo , Zheng Wenjun
Published: October 2010

The size‐ and shape‐controlled synthesis of Sb2S3 nanostructures has been successfully realized by a facile hydrothermal route. A range of dimensional nanostructures, such as one‐dimensional nanorods, two‐dimensional nanowire bundles, three dimensional sheaf‐like superstructures, dumbbell‐shaped superstructures, and urchin‐like microspheres, could be obtained through introducing different organic complex reagents or ionic liquids to the reaction system. The formation mechanisms of various Sb2S3 nanostructures have been rationally proposed based on the crystal structure and the nature of the complex reagents and the ionic liquid. The effects of experimental parameters on the final product are also discussed in detail. In addition, electrochemical measurements demonstrate that the as‐synthesized Sb2S3 nanostructures have higher initial Li intercalation capacity and excellent cyclic performances, which indicates that the as‐synthesized Sb2S3 nanostructures could have potential applications in commercial batteries.
Metal–Molecule–Metal Junctions in Langmuir–Blodgett Films Using a New Linker: Trimethylsilane
Authors: Pera Gorka , Martín Santiago , Ballesteros Luz M. , Hope Adam J. , Low Paul J. , Nichols Richard J. , Cea Pilar
Published: October 2010

Herein trimethylsilane (TMS) is demonstrated to be an efficient binding group suitable for construction of metal–molecule–metal (M–mol–M′) junctions, in which one of the metal contacts is an atomically flat gold surface and the other a scanning tunnelling microscopy (STM) tip. The molecular component of the M–mol–M′ devices is an oligomeric phenylene ethynylene (OPE) derivative Me3Si CC{C6H4CC}2C6H4NH2, featuring both Me3SiCC and NH2 metal contacting groups. This compound can be assembled into Langmuir–Blodgett (LB) films on Ausubstrates by surface binding through the amine groups. Alternatively, low coverage (sub‐monolayer) films are formed by adsorption from solution. In the case of condensed monolayers top electrical contacts are formed to STM tips through the TMS end group. In low coverage films, single molecular bridges can be formed between the gold surface and a gold STM tip. The similarity in the I–V response of a one‐layer LB film and the single molecule conductance experiments reveals several points of critical importance to the design of molecular components for use in the construction of M–mol–M′ junctions. Firstly, the presence of neighbouring π systems does not have a significant effect on the conductance of the M–mol–M′ junction. Secondly, in the STM configuration, intermolecular electron hopping does not significantly enhance the junction transport characteristics. Thirdly, the symmetric behaviour of the I–V curves obtained, despite the different metal–molecule contacts, indicates that the molecule is simply an amphiphilic electron‐donating wire and not a molecular diode with strong rectifying characteristics. Finally, the conductance values obtained from the amine/TMS‐contacted OPE described here are of the same order of magnitude as thiol anchored OPEs, making them attractive alternatives to the more conventionally used thiol‐contacting chemistry for OPE molecular wires.
New Iridium Catalysts for the Efficient Alkylation of Anilines by Alcohols under Mild Conditions
Authors: Michlik Stefan , Kempe Rhett
Published: October 2010

The synthesis of eight new iridium complexes containing anionic P,N ligands is described. These complexes have been investigated as catalysts for amine alkylation reactions, resulting in a highly active catalyst for the selective monoalkylation of anilines with primary alcohols, under mild reaction conditions. Nearly quantitative conversion was observed at 70 °C with a catalyst loading as low as 0.05 mol % iridium.
Unexpected Hydrobromic Acid‐Catalyzed CC Bond‐Forming Reactions and Facile Synthesis of Coumarins and Benzofurans Based on Ketene Dithioacetals
Authors: Yuan Hongjuan , Wang Mang , Liu Yingjie , Wang Lili , Liu Jun , Liu Qun
Published: October 2010

Hydrobromic acid was found to be a unique catalyst in CC bond‐forming reactions with ketene dithioacetals. Distinctly different from other acids (including Lewis and Brønsted acids), the remarkable catalytic performance of hydrobromic acid in catalytic amounts was observed in the “acid”‐catalyzed reactions of readily available functionalized ketene dithioacetals 1 with various electrophiles. Under the catalysis of 0.1 equivalents of hydrobromic acid, the reaction of 1 with carbonyl compounds 2 a–l gave polyfunctionalized penta‐1,4‐dienes 3 or conjugated dienes 4 in good to excellent yields. The reaction tolerated a broad range of substituents on both the ketene dithioacetals 1 and the carbonyl compounds 2. Application of this efficient CC bond‐forming method generated coumarins 5 and benzofurans 7 under mild, metal‐free conditions by hydrobromic acid‐catalyzed reactions of 1 with salicylaldehydes 2 m–o and p‐quinones 6 a–d, respectively. A new reactive species, a sulfur‐stabilized carbonium ylide, formed depending on the nature of the counterion, and this was proposed as the key intermediate in the unique catalysis of hydrobromic acid.
ChemInform Abstract: Polymorphism of Eu8In3 and the Solid Solution (CaxEu1‐x)8In3.
Authors: Gaebler Frank , Niewa Rainer
Published: October 2010

The new compounds Eu8In3 and Ca4Eu4In3 belonging to the title solid solution are characterized by single crystal XRD.
ChemInform Abstract: Structural Studies of the Disorder and Phase Transitions in the Double Perovskite Sr2YTaO6.
Authors: Zhou Qingdi , Kennedy Brendan J. , Avdeev Maxim
Published: October 2010

The evolution of the crystal structure of the title compound is monitored from room temperature to 1250 °C by powder neutron and synchrotron XRD.
ChemInform Abstract: Li4Ca3Si2N6 and Li4Sr3Si2N6 — Quaternary Lithium Nitridosilicates with Isolated [Si2N6]10‐ Ions.
Authors: Pagano Sandro , Lupart Saskia , Schmiechen Sebastian , Schnick Wolfgang
Published: October 2010

Single crystals of the isotypic nitridosilicates of title are synthesized by reaction of strontium or calcium with Si(NH)2 and excess Li3N (sealed tantalum tube, 900 °C, 48 h).
ChemInform Abstract: BaGa2Pn2 (Pn: P, As): New Semiconducting Phosphides and Arsenides with Layered Structures.
Authors: He Hua , Stearrett Ryan , Nowak Edmund R. , Bobev Svilen
Published: October 2010

The title compounds are prepared from the elements using an excess of Ga as flux (Ba:Ga:As,P = 1:10:2, 960 °C, alumina crucible in a sealed silica tube, 20 h).
ChemInform Abstract: Synthesis, Crystal Structure and Optical Investigation of the New Phosphates: Na7Mg13Ln(PO4)12 (Ln: La, Eu).
Authors: Jerbi Hasna , Hidouri Mourad , Glorieux Benoit , Darriet Jacques , Garcia Alain , Jubera Veronique , Amara Mongi Ben
Published: October 2010

Single crystals of the new title compounds are prepared by reaction of Na2CO3, MgCO3, Ln2O3 (Ln: La, Eu), and NH4H2PO4 using Na2MoO4 as a flux (Pt crucible, 1273 K, 2 h).
ChemInform Abstract: Synthesis and Crystal Structures of K2SnAs2 and a New Modification of NaAs.
Authors: Burtzlaff Susanne , Holynska Malgorzata , Dehnen Stefanie
Published: October 2010

The solid state reactions of Sn and As with potassium and sodium result in the formation of the new ternary Zintl compound (IV) and a new modification of the binary Zintl phase NaAs (VI) besides the known Na10Sn2As6 as the main product.
ChemInform Abstract: The Crystal Structure of Bi2W6Br18 and a New Synthesis of W6Br12.
Authors: Stroebele Markus , Meyer H.‐Juergen
Published: October 2010

The new compound Bi2W6Br18 is synthesized from mixtures of WBr6 and elementary Bi (silica tube, 350 °C, 48 h).
ChemInform Abstract: Mixed Valence Tungsten (IV,V) Compounds with Layered Structures. Part 3. Synthesis and Crystal Structure of Ag1‐x[W2O2Cl6] and Investigations on the Ag+ Ion Mobility.
Authors: Beck Johannes , Hoffbauer Wilfried , Kusterer Christian , Schieweling Marcel
Published: October 2010

Title compounds with x = 0, 0.38, and 0.82 are synthesized either by reaction of WOCl3 with AgCl in the presence of a small amount of WCl6 (510→700 K, 40 d), or by reaction of WOCl4 with metallic Ag (690 K, 7 d).
ChemInform Abstract: Chemoselective Catalysis with Organosoluble Lewis Acidic Polyoxotungstates.
Authors: Dupre Nathalie , Remy Pauline , Micoine Kevin , Boglio Cecile , Thorimbert Serge , Lacote Emmanuel , Hasenknopf Bernold , Malacria Max
Published: October 2010

New organosoluble polyoxometalates are shown to catalyze a series of Mannich [→ (III), (V), (VII)], aza‐Diels—Alder [→ (IX), (XI)], Mukaiyama‐type aldol [→ (XIV)], aminal [→ (XVI)], and three‐component Mannich reactions [→ (XVIII)].
ChemInform Abstract: Palladium‐Catalyzed Arylative Ring‐Opening Reactions of Norbornenols: Entry to Highly Substituted Cyclohexenes, Quinolines, and Tetrahydroquinolines.
Authors: Waibel Michael , Cramer Nicolai
Published: October 2010

Norbornene‐derived tertiary alcohols undergo the title reaction with aryl or vinyl halides and triflates to afford tetrasubstituted cyclohexenes with excellent regio‐ and diastereoselectivities.
ChemInform Abstract: Catalytic Asymmetric Reductive Amination of α‐Branched Ketones.
Authors: Wakchaure Vijay N. , Zhou Jian , Hoffmann Sebastian , List Benjamin
Published: October 2010

An efficient diastereo‐ and enantioselective synthesis of 2‐substituted cis‐cyclohexylamines, e.g. (III) involves organocatalytic dynamic kinetic resolution of α‐branched cyclohexanones.
ChemInform Abstract: Lewis Base Catalyzed Mukaiyama—Aldol Reaction of Trimethylsilyl Enolates with Aldehydes.
Authors: Zhang Xingxian , Shi Junchen , Hu Shenghui
Published: October 2010

A unique catalytic reactivity of alkoxymagnesium iodide as Lewis base in the Mukaiyama‐aldol condensation under mild reaction condition is established.
ChemInform Abstract: Synthesis of Some New Pyridones, Fused Pyrimidines, and Fused 1,2,4‐Triazines
Authors: Mohamed Mahmoud A.
Published: October 2010

via cyclocondensation reactions of salt (I) with hydrazides, amino‐substituted azoles and azole diazonium salts, respectively
ChemInform Abstract: Rapid Synthesis of Functionalized Indenes, Triazoles, and Glucocorticoid Receptor Modulators by Sequential Multicatalysis Cascade Reactions.
Authors: Ramachary Dhevalapally B. , Mondal Rumpa , Venkaiah Chintalapudi
Published: October 2010

The iminium activation of aldehydes, the self‐activation of olefins, and the simultaneous activation of metal ion alkynes are combined in a cascade sequence, constituting a new carbocyclization method to furnish indenes through a Conia‐ene reaction, and a new heterocyclization method to furnish 1,2,3‐triazoles through [3+2] cycloaddition.
ChemInform Abstract: β‐Fluoroamphetamines via the Stereoselective Synthesis of Benzylic Fluorides.
Authors: Cresswell Alexander J. , Davies Stephen G. , Lee James A. , Roberts Paul M. , Russell Angela J. , Thomson James E. , Tyte Melloney J.
Published: October 2010

Ring opening reaction of a variety of racemic and a chiral epoxide (I) is carried out in the presence of BF3·Et2O to afford syn‐fluorohydrins as major products.
ChemInform Abstract: MgBr2‐Mediated Opening of 2,3‐Three Membered Heterocyclic Amines.
Authors: Righi Giuliana , Ciambrone Simona , Esuperanzi Evelina , Montini Francesca , Pelagalli Romina
Published: October 2010

The regio‐ and stereo controlled opening of 2,3‐epoxy amines and 2,3‐aziridine amines by MgBr2 is studied.
ChemInform Abstract: Efficient Copper‐Catalyzed N‐Arylations of Nitrogen‐Containing Heterocycles and Aliphatic Amines in Water.
Authors: Li Xufeng , Yang Daoshan , Jiang Yuyang , Fu Hua
Published: October 2010

A simple and efficient, copper‐catalyzed method for the N‐arylation of nitrogen‐containing heterocycles and aliphatic amines is presented.
ChemInform Abstract: Amination of Aliphatic Alcohols and Diols with an Iridium Pincer Catalyst.
Authors: Andrushko Natalia , Andrushko Vasyl , Roose Peter , Moonen Kristof , Boerner Armin
Published: October 2010

Several aliphatic alcohols including those bearing functional groups are transformed to the corresponding amines by reaction with primary or secondary amines in the presence of catalyst IPA.
ChemInform Abstract: Room‐Temperature Highly Efficient Suzuki—Miyaura Reactions in Water in the Presence of Stilbazo.
Authors: Peng Yi‐Yuan , Liu Jinbiao , Lei Xiaoli , Yin Zenlan
Published: October 2010

The thirty‐six examples of the title reaction demonstrate the high functional group tolerance of the presented protocol.
ChemInform Abstract: Cross‐Coupling Reactions Through the Intramolecular Activation of Alkyl(triorgano)silanes.
Authors: Nakao Yoshiaki , Takeda Masahide , Matsumoto Takuya , Hiyama Tamejiro
Published: October 2010

A palladium/copper‐catalyzed transfer of both primary or secondary alkyl groups from [2‐(2‐hydroxyprop‐2‐yl)phenyl]‐substituted trialkylsilanes to aryl and alkenyl bromides or chlorides in the presence of K3PO4 as mild activator is reported to give a variety of alkylated arenes.
ChemInform Abstract: Ligand‐Free Palladium‐Catalyzed Mizoroki—Heck‐Type Reaction of Arylboronic Acids and Alkenes Using Silver Cation.
Authors: Song Eunjin , Park Jinhyung , Oh Il‐Kwon , Jung Hyun Min , Lee Sunwoo
Published: October 2010

Optimum reaction conditions are examined for the palladium‐catalyzed Mizoroki—Heck‐type reaction of arylboronic acids with alkenes in the presence of AgOAc.
ChemInform Abstract: Rhodium‐Catalyzed Pauson—Khand‐Type Reaction Using Alcohol as a Source of Carbon Monoxide.
Authors: Park Ji Hoon , Cho Yoonhee , Chung Young Keun
Published: October 2010

A new version of an auto‐tandem catalytic intramolecular Pauson—Khand‐type reaction is developed.
ChemInform Abstract: Copper‐Catalyzed Amination of Alkenyl Halides: Efficient Method for the Synthesis of Enamines.
Authors: Wang Yuxing , Liao Qian , Xi Chanjuan
Published: October 2010

Alkenyl iodides and bromides and a variety of secondary amines are applied to afford the desired enamines with good yields and selectivity.
ChemInform Abstract: Bi2O3‐Catalyzed Oxidation of Aldehydes with t‐BuOOH.
Authors: Malik Payal , Chakraborty Debashis
Published: October 2010

The inexpensive catalytic method, which needs neither ligands nor additives, allows the high‐yielding oxidation of aliphatic and aromatic aldehydes within a reasonable time.
ChemInform Abstract: Mild and Efficient Deoxygenation of Sulfoxides to Sulfides Using HfCl4/KBH4 System.
Authors: Zhang Jianghua , Gao Xinqin , Zhang Chengyi , Zhang Cheng , Luan Jiming , Zhao Defeng
Published: October 2010

Sulfoxides are conveniently reduced to sulfides with potassium borohydride in the presence of 1 equiv.
ChemInform Abstract: Palladium Acetate Catalyzed Oxidative Aromatization of Methylenecyclopropanes.
Authors: Jiang Min , Wei Yin , Shi Min
Published: October 2010

Isopropenylbiaryl derivatives are formed under palladium catalysis through dehydrogenated rearrangement of alkenes (I).
ChemInform Abstract: Ligand‐Free Suzuki—Miyaura Reactions in PEG 300.
Authors: Silva Aires da Conceicao , Senra Jaqueline Dias , Aguiar Lucia C. S. , Simas Alessandro B. C. , de Souza Andrea Luzia F. , Malta Luiz Fernando Brum , Antunes O. A. C.
Published: October 2010

Optimized reaction conditions afford biaryl compounds (III) in high yields.
ChemInform Abstract: Water‐Promoted Unprecedented Chemoselective Nucleophilic Substitution Reactions of 1,4‐Quinones with Oxygen Nucleophiles in Aqueous Micelles.
Authors: Tandon Vishnu K. , Maurya Hardesh K.
Published: October 2010

The reaction of halogenated benzo‐ and naphthoquinones proceeds in water in the presence of SDS to give mono‐ or disubstituted products.
ChemInform Abstract: A Simple Quick Route to Fullerene Amino Acid Derivatives.
Authors: Strom T. Amanda , Barron Andrew R.
Published: October 2010

Several novel fullerene amino acid derivatives, e.g. compounds (III) and (IV), are prepared and readily separated with flash chromatography.
ChemInform Abstract: Rhodium‐Catalyzed Hydroformylation of N‐(2‐Propenyl)‐β‐lactams as a Key Step in the Synthesis of Functionalized N‐[4‐(2‐Oxoazetidin‐1‐yl)but‐1‐enyl]acetamides.
Authors: Dekeukeleire Stijn , D'hooghe Matthias , Mueller Christian , Vogt Dieter , De Kimpe Norbert
Published: October 2010

Biologically relevant functionalized N‐[4‐(2‐oxoazetidin‐1‐yl)but‐1‐enyl]acetamides are synthesized starting from N‐(2‐propenyl)‐β‐lactams in a two‐step procedure.
ChemInform Abstract: Lewis Acid Catalyzed Reactions of Methylenecyclopropylcarbinols with Acetals for the Construction of 3‐Oxabicyclo[3.1.0]hexane Derivatives.
Authors: Shao Li‐Xiong , Shi Min
Published: October 2010

The reaction is catalyzed by the fluorinated Sc(OPf)3 and proceeds with high selectivity.
ChemInform Abstract: Acid‐Catalyzed or Radical‐Promoted Allylic Substitution of 2‐Methylene‐2,3‐dihydrobenzofuran‐3‐ols with Thiol Derivatives: A Novel and Expedient Synthesis of 2‐(Thiomethyl)benzofurans.
Authors: Gabriele Bartolo , Mancuso Raffaella , Salerno Giuseppe
Published: October 2010

Readily available 2‐methylene‐2,3‐dihydrobenzofuran‐3‐ols are smoothly converted into 2‐thiomethylbenzofurans by acid‐catalyzed or radical‐promoted allylic substitution with thiol derivatives under mild conditions.
ChemInform Abstract: Diastereoselective Syntheses of Functionalized Five‐Membered Carbocycles and Heterocycles by a SmI2‐Promoted Intramolecular Coupling of Bromoalkynes and α,β‐Unsaturated Esters.
Authors: Takahashi Kazunori , Honda Toshio
Published: October 2010

The use of HFIP as a proton source and HMPA as a co‐solvent is crucial to obtain the heterocyclic products in high yields.
ChemInform Abstract: Gold Catalyzed Cycloisomerization Reactions of 2‐Tosylaminophenylprop‐1‐yn‐3‐ols as a Versatile Approach for Indole Synthesis.
Authors: Kothandaraman Prasath , Rao Weidong , Foo Shi Jia , Chan Philip Wai Hong
Published: October 2010

A wide range of 2,3‐disubstituted indoles is readily formed by cycloisomerization of o‐aminophenylpropynols, e.g. (V) or (VII), in the presence of a Au(I)—Ag(I)—HMPA catalyst system.
ChemInform Abstract: Efficient Alkylation Methods for the Synthesis of Hybrid Fluorocarbon—Hydrocarbon Tetrazoles as Potential Fluorinated Surfactants.
Authors: Huang Yangen , Read Roger W. , Wang Xiaobei
Published: October 2010

The present new base‐catalyzed, direct alkylation of 5‐alkylated tetrazoles (I) with fluorinated iodide (II), fluorinated alcohol (V), and fluorinated triflate (VI) provides access to two new classes of fluorinated tetrazoles.
ChemInform Abstract: Diselenide‐ and Disulfide‐Mediated Synthesis of Isocoumarins.
Authors: Shahzad Sohail A. , Venin Claire , Wirth Thomas
Published: October 2010

A diselenide‐ or disulfide‐catalyzed approach to the synthesis of isocoumarins is developed by employing hypervalent iodine reagents under very mild reaction conditions.
ChemInform Abstract: Diastereoselective Synthesis of Nicotine Derivatives via 1,3‐Dipolar Cycloaddition Reactions.
Authors: Ghandi Mehdi , Taheri Abuzar , Abbasi Alireza
Published: October 2010

Nicotine derivatives (IV) are obtained via a one‐pot three‐component 1,3‐dipolar cycloaddition reaction of the Knoevenagel adducts (II) of aromatic aldehydes and malononitrile with an azomethine ylide, generated in situ from pyridinecarbaldehyde (I) and sarcosine (III).
ChemInform Abstract: Quinolone Analogues. Part 10. Synthesis of Antimalarial Quinolones Having Pyridyl Moiety in N1‐Side Chain.
Authors: Kurasawa Yoshihisa , Yoshida Kiminari , Yamazaki Naoki , Kaji Eisuke , Sasaki Kenji , Hiwasa Yoshiko , Tsukamoto Akiko , Ito Hideyuki
Published: October 2010

Among the new title compounds the diester (IIIb) shows weak antimalarial activity against Plasmodium falciparum.
ChemInform Abstract: Regiospecific Three‐Component Access to Fluorescent 2,4‐Disubstituted Quinolines via One‐Pot Coupling‐Addition‐Cyclocondensation‐Sulfur Extrusion Sequence.
Authors: Rotzoll Sven , Willy Benjamin , Schoenhaber Jan , Rominger Frank , Mueller Thomas J. J.
Published: October 2010

A versatile and regiospecific microwave‐assisted one‐pot three‐component synthesis of 2,4‐di‐ and 2,4,7‐trisubstituted quinolines by a consecutive, microwave‐assisted one‐pot three‐component coupling—cyclocondensation—sulfur extrusion sequence is described.
ChemInform Abstract: Intramolecular Substitution Reactions Involving π‐Nucleophiles and N‐Acyliminium Cations Generated from Azetidin‐2‐ones.
Authors: Grzeszczyk Barbara , Szechner Barbara , Furman Bartlomiej , Chmielewski Marek
Published: October 2010

The formation of carbapenams is not observed in the present reactions.
ChemInform Abstract: Solvent‐Free Synthesis of Monastrol Derivatives Catalyzed by NaHSO4.
Authors: Cheng Qingfang , Wang Qifa , Xu Xingyou , Ruan Mingjie , Yao Hailun , Yang Xujie
Published: October 2010

An environmentally friendly three‐ component Biginelli cyclocondensation is used for the synthesis of monastrol derivatives which are an interesting class of compounds in cancer research.Depending on the combination of the three components products of type (IV) or (VII) are obtained.
ChemInform Abstract: Mild and Efficient Oxidative Aromatization of 4‐Substituted‐1,4‐dihydropyrimidines Using (Diacetoxyiodo)benzene.
Authors: Karade Nandkishor N. , Gampawar Sumit V. , Tale Nilesh P. , Kedar Sanjay B.
Published: October 2010

(Diacetoxyiodo)benzene is used as a transition metal free and safe oxidizing agent of 4‐substituted 1,4‐dihydropyrimidines to give the corresponding pyrimidines.
ChemInform Abstract: Synthesis and Pharmacological Screening of Derivatives of Isoxazolo[4,3‐d]pyrimidine and Isoxazolo[4,5‐d]pyrimidine.
Authors: Wagner Edwin , Al‐Kadasi Kamal , Becan Lilianna , Sawka‐Dobrowolska Wanda
Published: October 2010

Compounds (IIIc), (Va) and (XIVb) exhibit interesting activity in the panel 62 tumor cell lines, but chiefly on the renal cancer line UO‐31.
ChemInform Abstract: An Efficient One‐Pot Three‐Component Synthesis of 4‐Phenylhexahydro‐1H‐pyrano[2,3‐d]pyrimidin‐2(8aH)‐one Derivatives.
Authors: Vuppalapati Srinivasu V. N. , Lingaiah Rajashekar Bantu , Kantevari Srinivas
Published: October 2010

The reaction between aromatic aldehydes, dihydropyran and urea leads to diastereomerically pure products.
ChemInform Abstract: NbCl5 as an Efficient Catalyst for Rapid Synthesis of Quinoxaline Derivatives.
Authors: Hou Jun‐Tao , Liu Yong‐Hui , Zhang Zhan‐Hui
Published: October 2010

Key advantages of the title method are simplicity of operation, short reaction times, and good substrate generality.
ChemInform Abstract: MoO2Cl2(dmf)2‐Catalyzed Domino Reactions of ω‐Nitro Alkenes to 3,4‐Dihydro‐2H‐1,4‐benzothiazines and Other Heterocycles.
Authors: Malakar Chandi C. , Merisor Elena , Conrad Juergen , Beifuss Uwe
Published: October 2010

The optimized procedure affords the N‐heterocycles highly selectively.
ChemInform Abstract: A Facile and Efficient Synthesis of Arylsulfonamido‐Substituted 1,5‐Benzodiazepines and N‐[2‐(3‐Benzoylthioureido)aryl]‐3‐oxobutanamide Derivatives.
Authors: Alizadeh Abdolali , Zohreh Nasrin
Published: October 2010

The reaction of 1,2‐diamine (I), diketene (II) and arylsulfonyl isocyanate (III) or benzoylisothiocyanate (V) leads to the formation of the corresponding title compounds.
ChemInform Abstract: Synthesis of Crown Compounds Containing a 1,3,4‐Oxadiazole Moiety: Microwave‐Assisted Synthesis.
Authors: Outirite Moha , Lebrini Mounim , Lagrenee Michel , Bentiss Fouad
Published: October 2010

Contrary to the microwave‐assisted method no reaction product is obtained under conventional heating.
ChemInform Abstract: Synthesis and Bio‐Activity of Alkyl/Aryl [2‐(1,2,4,5‐Tetrahydro‐3‐sulfanylene/selenylene naphtha[1,8][1,5,3]diazaphosphocin‐3‐yl)methyl amino acid esters].
Authors: Reddy S. Subba , Rao V. K. , Sankar A. U. Ravi , Raju C. N.
Published: October 2010

The synthesis of the eight‐membered phosphorus heterocyclic compounds (VI) and (VIII) is accomplished in three steps involving the cyclization of diaminonaphthalene (I) with tris(bromomethyl)phosphine (II), conversion of the naphthodiazaphosphocine (III) (no yield given) to the corresponding sulfide (IV) and selenide (VII), and reaction of the latter compounds with amino acid esters (V).
ChemInform Abstract: A Cleistanthane Diterpene from a Marine‐Derived Fusarium Species under Submerged Fermentation.
Authors: Shiono Yoshihito , Ogata Kota , Koseki Takuya , Murayama Tetsuya , Funakoshi Takayuki
Published: October 2010

Isolation and structure determination of 14‐epi‐zythiostromic acid B (I) are described.
ChemInform Abstract: A New Limonoid from Trichilia connaroides
Authors: Geng Zhao‐Liang , Fang Xin , Di Ying‐Tong , Zhang Qiang , Shen Yue‐Mao , Hao Xiao‐Jiang
Published: October 2010

structure and in vitro cytotoxicity of trichiliton (I)
ChemInform Abstract: Novel C‐Aryl Glucoside SGLT2 Inhibitors as Potential Antidiabetic Agents: Pyridazinylmethylphenyl Glucoside Congeners.
Authors: Lee Jinhwa , et al. et al.
Published: October 2010

Among a variety of pyridazines the derivatives (I) show the best in vitro inhibition against SGLT2 (sodium‐dependent glucose cotransporter).
ChemInform Abstract: A Rapid Entry to C‐Prenylcarbazoles: Total Synthesis of Clausamine C—D (IVb), (IIIc), Clausevatine D (IVa) and Clausine F (IIIb).
Authors: Jana Amit Kumar , Mal Dipakranjan
Published: October 2010

A Claisen rearrangement, the selective removal of a methoxycarbonyl group and an unusual oxidative cyclization are the key steps of the title syntheses.
ChemInform Abstract: Synthesis of 5‐(3‐Indolyl)oxazole Natural Products. Structure Revision of Almazole D.
Authors: Miyake Fumiko , Hashimoto Michinao , Tonsiengsom Sorasaree , Yakushijin Kenichi , Horne David A.
Published: October 2010

Use of β‐oxytryptophan ester (I) in the synthesis of title indolyloxazole natural products leads to revision of the structure of antibiotic almazole D as compound (IV).
ChemInform Abstract: Organocatalytic Michael Addition of Aldehydes to Protected 2‐Amino‐1‐nitroethenes: The Practical Syntheses of Oseltamivir (Tamiflu) and Substituted 3‐Aminopyrrolidines.
Authors: Zhu Shaolin , Yu Shouyun , Wang You , Ma Dawei
Published: October 2010

N‐Protected nitroenamines undergo organocatalytic stereoselective Michael reaction towards aliphatic aldehydes to afford β‐amino‐γ‐nitroaldehydes in good yields and stereoselectivities.
ChemInform Abstract: 8‐THP‐DHI Analogues as Potent Type I Dual TIE‐2/VEGF‐R2 Receptor Tyrosine Kinase Inhibitors.
Authors: Hudkins Robert L , et al. et al.
Published: October 2010

A series of 17 title compounds of type (I) are prepared by conventional procedures.
ChemInform Abstract: Vanadium Oxide Aerogels: Nanostructured Materials for Enhanced Energy Storage
Authors: Augustyn Veronica , Dunn Bruce
Published: October 2010

Review: 45 refs.
ChemInform Abstract: Oxygen Reduction and Transportation Mechanisms in Solid Oxide Fuel Cell Cathodes
Authors: Li Yihong , Gemmen Randall , Liu Xingbo
Published: October 2010

Review: 83 refs.
ChemInform Abstract: Magnetic Properties of Filled Skutterudites
Authors: Sato H. , Sugawara H. , Aoki Y. , Harima H.
Published: October 2010

Review: 337 refs.
ChemInform Abstract: Active Sites in Fe/ZSM‐5 Zeolite
Authors: Yang Gang , Guan Jing , Zhou Lijun , Han Xiuwen , Bao Xinhe
Published: October 2010

Review: 54 refs.
ChemInform Abstract: An Iron Step Towards N2 Fixation
Authors: Field Leslie D.
Published: October 2010

Review: 10 refs.
ChemInform Abstract: Hybrid Materials Through Linkage of Chalcogenide Tetrahedral Clusters
Authors: Vaqueiro Paz
Published: October 2010

Review: 65 refs.
ChemInform Abstract: Recent Developments on Chiral P,S‐Type Ligands and Their Applications in Asymmetric Catalysis
Authors: Lam Fuk Loi , Kwong Fuk Yee , Chan Albert S. C.
Published: October 2010

Review: 78 refs.
ChemInform Abstract: Dialkyl Acetone‐1,3‐dicarboxylates and Their Mono‐ and Bis(dimethylamino)methylidene Derivatives in the Synthesis of Heterocyclic Systems
Authors: Stanovnik Branko , Groselj Uros
Published: October 2010

Review: about 100 refs.
ChemInform Abstract: Pd‐Catalyzed Carbonylations: Versatile Technolgy for Discovery and Process Chemists
Authors: Grigg Ronald , Mutton Simon P.
Published: October 2010

Review: 210 refs.
ChemInform Abstract: Folding and Self‐Assembly of Aromatic and Aliphatic Urea Oligomers: Towards Connecting Structure and Function
Authors: Fischer Lucile , Guichard Gilles
Published: October 2010

Review: 186 refs.
ChemInform Abstract: Nanocarbonic Transparent Conductive Films
Authors: Roth Siegmar , Park Hye Jin
Published: October 2010

Review: 51 refs.
ChemInform Abstract: Water/Alcohol Soluble Conjugated Polymers as Highly Efficient Electron Transporting/Injection Layer in Optoelectronic Devices
Authors: Huang Fei , Wu Hongbin , Cao Yong
Published: October 2010

Review: 135 refs.
ChemInform Abstract: Chiral Conducting Polymers
Authors: Kane‐Maguire Leon A. P. , Wallace Gordon G.
Published: October 2010

Review: 153 refs.
ChemInform Abstract: Electroactive Materials for Organic Electronics: Preparation Strategies, Structural Aspects and Characterization Techniques
Authors: Pron Adam , Gawrys Pawel , Zagorska Malgorzata , Djurado David , Demadrille Renaud
Published: October 2010

Review: ca. 450 refs.
ChemInform Abstract: Organic Crystals: Properties, Devices, Functionalization and Bridges to Bio‐Molecules
Authors: Brooks James S.
Published: October 2010

Review: 155 refs.
ChemInform Abstract: Pseudolaric Acids: Isolation, Bioactivity and Synthetic Studies
Authors: Chiu Pauline , Leung Lai To , Ko Ben C. B.
Published: October 2010

Review: 127 refs.
ChemInform Abstract: Applications and Trends in Electrochemiluminescence
Authors: Hu Lianzhe , Xu Guobao
Published: October 2010

Review: 322 refs.
ChemInform Abstract: Charge‐Transfer Interactions in Organic Functional Materials
Authors: Lin Hsin‐Chieh , Jin Bih‐Yaw
Published: October 2010

Review: 130 refs.
ChemInform Abstract: The Impact of Oxacarbenium Ion Conformers on the Stereochemical Outcome of Glycosylation
Authors: Walvoort Marthe T. C. , Dinkelaar Jasper , van den Bos Leendert J. , Lodder Gerrit , Overkleeft Herman S. , Codee Jeroen D. C. , van der Marel Gijsbert A.
Published: October 2010

Review: 101 refs.
ChemInform Abstract: Isokinetic Relationships in Unimolecular Heterolysis. Mechanism of Ionization of Covalent Bond
Authors: Dvorko G. F. , Ponomarev N. E. , Ponomareva E. A.
Published: October 2010

Review: 91 refs.
ChemInform Abstract: Targeted Metabolomics for Biomarker Discovery
Authors: Griffiths William J. , Koal Therese , Wang Yuqin , Kohl Matthias , Enot David P. , Deigner Hans‐Peter
Published: October 2010

Review: 194 refs.
Perspectives for a Resource Efficient Industrialized Society
Authors: Köglmeier M. , Faulstich M. , Mocker M. , Leipprand A.
Published: October 2010

Neben den allseits diskutierten endlichen Energierohstoffen rücken derzeit die ebenso knappen metallischen und mineralischen Rohstoffe verstärkt in den Fokus von Wirtschaft, Politik und Forschung. Die geforderte Steigerung der Rohstoff‐ und Materialeffizienz kann prinzipiell auf allen Ebenen der Wertschöpfungskette erfolgen. Eine systematische Analyse liefert sowohl Ansatzpunkte beim Rohstoffabbau und der Grundstoffproduktion, welche allerdings nur begrenztes Potenzial zur Materialeinsparung besitzen, als auch auf den Ebenen der Güterproduktion und Güternutzung sowie der Abfallwirtschaft. Diese letztgenannten Wertschöpfungsstufen stellen den weitaus größeren Hebel dar. Allerdings erfordern konkrete Maßnahmen wie materialeffizientes Design, optimierte Produktionsprozesse, Leasing‐Modelle oder Urban‐Mining eine möglichst international abgestimmte, integrierte Politik und eine spürbare Veränderung im Nutzerverhalten.
Crushed recycled glass as a filter medium and comparison with silica sand
Authors: Soyer Elif , Akgiray Ömer , Eldem Nursen Öz , Saatçı Ahmet Mete
Published: October 2010

The objective of this work was to evaluate crushed recycled glass as a medium for rapid filtration. In the first part of this work, physical and hydraulic characteristics of the glass medium were studied. In the second part, pilot scale inline filtration experiments were carried out using raw waters from three different water sources. Two physically identical filter columns were operated in parallel in all the experiments. One filter contained a silica sand medium that is widely used in Turkey, whereas the other filter contained crushed recycled glass. Experiments were repeated five times as follows: (i) Without the use of a coagulant, (ii–iii) with 5 mg/L and 10 mg/L of alum, and (iv–v) with 5 mg/L and 10 mg/L of ferric chloride. Turbidity, particle counts, and head losses were measured and compared as functions of time. The following were observed: (1) Provided that a coagulant was used, the filter containing crushed glass produced effluent turbidities and particle counts similar to those obtained with the sand filter. (2) The crushed glass medium generated both a smaller clean‐bed head loss and smaller clogging head losses than those of the sand filter. It is concluded that crushed glass shows significant promise as an alternative to silica sand in rapid filtration.