bluuebunny/crossref_metadata_2025 huggingface dataset:
Laser microdissection system based on structured light modulation dual cutting mode and negative pressure adsorption collection
Authors: Zhou Bocong , Huang Caihong , Yi Dingrong
Published: August 2024

Laser microdissection technology is favored by biomedical researchers for its ability to rapidly and accurately isolate target cells and tissues. However, the precision cutting capabilities of existing laser microdissection systems are hindered by limitations in overall mechanical movement accuracy, resulting in suboptimal cutting quality. Additionally, the use of current laser microdissection systems for target acquisition may lead to tissue burns and reduced acquisition rates due to inherent flaws in the capture methods. To address these challenges and achieve precise and efficient separation and capture of cellular tissues, we integrated a digital micromirror device (DMD) into the existing system optics to modulate spatial light. This allows the system to not only implement the traditional point scanning cutting method but also utilize the projection cutting method.We have successfully cut various patterns on commonly used laser microdissection materials such as PET films and mouse tissues. Under projection cutting mode, we were able to achieve precise cutting of special shapes with a diameter of 7.5 micrometers in a single pass, which improved cutting precision and efficiency. Furthermore, we employed a negative pressure adsorption method to efficiently collect target substances. This approach not only resulted in a single-pass capture rate exceeding 90% for targets of different sizes but also enabled simultaneous capture of multiple targets, overcoming the limitations of traditional single-target capture and enhancing target capture efficiency, and avoiding potential tissue damage from lasers.In summary, the integration of the digital micromirror device into laser microdissection systems significantly enhances cutting precision and efficiency, overcoming limitations of traditional systems. This advancement demonstrates the accuracy and effectiveness of laser microdissection systems in isolating and capturing biological tissues, highlighting their potential in medical applications.
Cross-sectional study of self-reported pain related to temporomandibular disorders and emotional state of medical school faculty and students: Post-COVID-19 pandemic
Authors: Galhardo Alessandra Pucci Mantelli , Andrade Pâmela Ramos , Andrade Luciana Paes de , Cury Mariluce Anache Anbar , Mukai Marcio Katsuyoshi , Baracat Edmund Chada , Soares Jr. José Maria
Published: August 2024

The social isolation imposed by the COVID-19 pandemic interrupted in-person activities, which were immediately followed by adaptations to ensure, for example, the continuity of teaching. This generated emotional impacts on the academic community. Emotional states may trigger or emphasize conditions such as temporomandibular dysfunction (TMD), causing pain and limiting masticatory function. This study aimed to compare the students and the faculty of a medical school first in terms of the TMD-caused pain they experienced during social isolation and reported two months later, according to their recollections, using the TMD-Pain Screener questionnaire. The second basis for comparison was the emotional state generated by social isolation and its connection with TMD symptoms assessed through the Depression, Anxiety and Stress Scale (DASS-21), which considers perceptions at the time of data collection. Both questionnaires were responded to in May 2022 after the end of social isolation. The data were analyzed by the IBM-SPSS software for Windows 22.0 with a 5% level of significance. The results show that the self-reported TMD symptoms were more widespread (p = 0.002) and intense (p = 0.013) among students than among faculty and that all of the former’s DASS-21 domains (depression, anxiety, and stress) were also more strongly evident (p<0.05). Only anxiety was more significant among the faculty (p = 0.027). Both groups pointed to social isolation as an aggravating factor of the symptoms (p<0.05). The conclusion is that the self-reported TMD-caused pain and all DASS-21 domains as experienced during social isolation were stronger and more prevalent among students than among faculty, and that only anxiety was statistically significant among faculty. Also, the emotional states resulting from social isolation may have aggravated TMD-caused pain in both groups.
Unpacking Galvanic Vestibular Stimulation using simulations and relating current flow to reported motions: Comparison across common and specialized electrode placements
Authors: Truong Dennis Q. , Thomas Chris , Ira Sanjidah , Valter Yishai , Clark Torin K. , Datta Abhishek
Published: August 2024

Background

Galvanic Vestibular Stimulation (GVS) is a non-invasive electrical stimulation technique that is typically used to probe the vestibular system. When using direct current or very low frequency sine, GVS causes postural sway or perception of illusory (virtual) motions. GVS is commonly delivered using two electrodes placed at the mastoids, however, placements involving additional electrodes / locations have been employed. Our objective was to systematically evaluate all known GVS electrode placements, compare induced current flow, and how it relates to the archetypal sway and virtual motions. The ultimate goal is to help users in having a better understanding of the effects of different placements.

Methods

We simulated seven GVS electrode placements with same total injected current using an ultra-high resolution model. Induced electric field (EF) patterns at the cortical and the level of vestibular organs (left and right) were determined. A range of current flow metrics including potential factors such as inter-electrode separation, percentage of current entering the cranial cavity, and symmetricity were calculated. Finally, we relate current flow to reported GVS motions.

Results

As expected, current flow patterns are electrode placement specific. Placements with two electrodes generally result in higher EF magnitude. Placements with four electrodes result in lower percentage of current entering the cranial cavity. Symmetric placements do not result in similar EF values in the left and the right organs respectively- highlighting inherent anatomical asymmetry of the human head. Asymmetric placements were found to induce as much as ~3-fold higher EF in one organ over the other. The percentage of current entering the cranial cavity varies between ~15% and ~40% depending on the placement.

Conclusions

We expect our study to advance understanding of GVS and provide insight on probable mechanism of action of a certain electrode placement choice. The dataset generated across several metrics will support hypothesis testing relating empirical outcomes to current flow patterns. Further, the differences in current flow will guide stimulation strategy (what placement and how much scalp current to use) and facilitate a quantitatively informed rational / optimal decision.
Advancing 7T perfusion imaging by pulsed arterial spin labeling: Using a parallel transmit coil for enhanced labeling robustness and temporal SNR
Authors: Oliveira Ícaro Agenor Ferreira , Schnabel Robin , van Osch Matthias J. P. , Zwaag Wietske van der , Hirschler Lydiane
Published: August 2024

Non-invasive perfusion imaging by Arterial spin labeling (ASL) can be advantageous at Ultra-high field (UHF) MRI, since the image SNR and the T1 relaxation time both increase with the static field. However, ASL implementation, especially at 7T, is not trivial. Especially for ASL, UHF MRI comes with many challenges, mainly due to B1+ inhomogeneities. This study aimed to investigate the effects of different transmit coil configurations on perfusion-weighted imaging at 7T using a flow-sensitive alternating inversion recovery (FAIR) technique with time-resolved frequency offset corrected inversion (TR-FOCI) pulses for labeling and background suppression. We conducted a performance comparison between a parallel transmit (pTx) system equipped with 32 receive (Rx) and 8 transmit (Tx) channels and a standard setup with 32Rx and 2Tx channels. Our findings demonstrate that the pTx system, characterized by a more homogeneous B1 transmit field, resulted in a significantly higher contrast-to-noise ratio, temporal signal-to-noise ratio, and lower coefficient of variance (CoV) than the standard 2Tx setup. Additionally, both setups demonstrated comparable capabilities for functional mapping of the hand region in the motor cortex, achieving reliable results within a short acquisition time of approximately 5 minutes.
Corynebacterium pseudotuberculosis: Whole genome sequencing reveals unforeseen and relevant genetic diversity in this pathogen
Authors: Hiller Ekkehard , Hörz Verena , Sting Reinhard
Published: August 2024

Corynebacterium pseudotuberculosis (CPS) is an important bacterial animal pathogen. CPS causes chronic, debilitating and currently incurable infectious diseases affecting a wide range of livestock and wild herbivores including camelids worldwide. Belonging to the Corynebacterium diphtheriae complex, this pathogen can also infect humans. The classical characterization of CPS is typically based on the testing of nitrate reductase activity, separating the two biovars Equi and Ovis. However, more refined resolutions are required to unravel routes of infection. This was realized in our study by generating and analyzing whole genome sequencing (WGS) data. Using newly created core genome multilocus sequence typing (cgMLST) profiles we were the first to discover isolates grouping in a cluster adjacent to clusters formed by CPS biovar Equi isolates. This novel cluster includes CPS isolates from alpacas, llamas, camels and dromedaries, which are characterized by a lack of nitrate reductase activity as encountered in biovar Ovis. This is of special interest for molecular epidemiology. Nevertheless, these isolates bear the genes of the nitrate locus, which are characteristic of biovar Equi isolates. However, sequence analysis of the genes narG and narH of the nitrate locus revealed indels leading to frameshifts and inactivity of the enzymes involved in nitrate reduction. Interestingly, one CPS isolate originating from another lama with an insertion in the MFS transporter (narT) is adjacent to a cluster formed by ovine CPS isolates biovar Equi. Based on this knowledge, the combination of biochemical and PCR based molecular biological nitrate reductase detection can be used for a fast and uncomplicated classification of isolates in routine diagnostics in order to check the origin of camelid CPS isolates. Further analysis revealed that partial sequencing of the ABC transporter substrate binding protein (CP258_RS07935) is a powerful tool to assign the biovars and the novel genomovar.
The impact of AR online shopping experience on customer purchase intention: An empirical study based on the TAM model
Authors: Guo Chunrong , Zhang Xiaodong
Published: August 2024

Augmented Reality (AR) offers a rich business format, convenient applications, great industrial potential, and strong commercial benefits. The integration of AR technology with online shopping has brought tremendous changes to e-commerce. The Technology Acceptance Model (TAM) is a mature model for assessing consumer acceptance of new technologies, and applying it to evaluate the impact of AR online shopping experiences on consumer purchase intention is an urgently needed area of research. Firstly, the typical applications of AR in online shopping were reviewed, and the connotations and experiences of AR online shopping were summarized. Secondly, using the five types of AR online shopping experiences as antecedent variables, and perceived ease of use and perceived usefulness as intermediate variables, a theoretical model was constructed to explore the impact of AR online shopping experiences on customer purchase intentions, followed by an empirical study. Finally, suggestions were proposed for optimizing the online shopping experience to enhance purchase intentions. The article expands the application scenarios of the Technology Acceptance Model and enriches the theory of consumer behavior in Metaverse e-commerce.
A tanulói jóllét, vagyis az adaptivitás fokozása a meglepetés, nyitottság, érdeklődés és kíváncsiság dinamikus rendszerében
Authors: Túri Krisztina
Published: August 2024

A tanulói jóllét, vagyis az adaptivitás fokozása a meglepetés, nyitottság, érdeklődés és kíváncsiság dinamikus rendszerében. A legfrissebb kognitív, pozitív pszichológiai és interperszonális idegtudományi kutatások értelmezésében a kíváncsiság, a kreativitással és kollaboratív tanulással együtt elősegíti az egyén integrált állapotát, amely katalizátora az interperszonális és intraperszonális növekedésnek, motivációnak és jóllétnek.
A tanulmány célkitűzése, hogy bemutassa és részletezze az integrációs folyam, mint jóllét terének komponenseit. Arra is keresi a választ, hogy a meglepetés, nyitottság, érdeklődés és kíváncsiság milyen relációban állnak egymással, milyen értelmezések húzódnak meg a fogalmak mögött és dinamikus rendszerük milyen és mekkora jelentőséggel bír az egyén integrációjában.
A tanulmány tárgyalja Hidi & Renninger Érdeklődés Fejlődésének Négy-Fázisú, illetve az Önszabályozás Érdeklődés-Motivációs modelljeit. Kitér a kíváncsiság tipológiájára, úgy, mint perceptuális, episztemikus, specifikus és diverzív kíváncsiságra. A kíváncsiság értelemzési keretében igyekszik áttekinteni a kíváncsiság és Proximális Tanulási Terület kapcsolódási pontjait, az információs rés fogalmát, valamint az I- és D-típusú kíváncsiságnak osztályozását és dinamikáját.
A gyakorlati tanulásszervezés területén az önszabályozási stratégiákat illetően tárgyalja Ryan and Deci Organizmikus Integrációs Elmélet modelljét. Mindemellett pedig hathatós eszköztárat kínál a kíváncsiság felkeltésére és fenntartására.
Óvodapedagógusok véleménye a technológiai területhez kapcsolódó képességek fejlesztéséről az óvodában
Authors: Bálint-Svella Éva , Zsoldos-Marchiș Iuliana
Published: August 2024

Az óvodáskor a formális oktatás azon szakasza, mely a kulcskompetenciák megalapozásáért felelős. A jelenleg Romániában érvényben lévő „Koragyermekkori nevelés curriculuma” a kulcskompetenciák közé sorolja a digitális kompetenciákat, de nem részletezi, hogyan és milyen tartalmakkal lehet ezeket fejleszteni az óvodában. A szakirodalom kihangsúlyozza, hogy ezeket a kompetenciákat lehet és szükséges már óvodás kortól fejleszteni. A jelen kutatás az óvodapedagógusok véleményét és tapasztalatait mutatja be a technológiai ismeretek bevezetéséről az óvodába, különös hangsúlyt fektetve az algoritmikus és számítógépes gondolkodás fejlesztésére. A kutatás eszköze egy online, a szerzők által kidolgozott kérdőív, mely zárt és nyitott kérdéseket is tartalmaz. A kérdőívet 115 óvodapedagógus töltötte ki. Az eredmények azt mutatják, hogy az óvodapedagógusok nem tartják nagyon fontosnak a technológiai ismeretek bevezetését az óvodában és a válaszadók kevesebb mint fele próbált ilyen ismereteket bevinni a tevékenységekbe. Az algoritmikus gondolkodás fejlesztését az óvópedagógusok 91%-a tartja fontosnak és háromnegyede látja megvalósulni a különböző óvodai tevékenységek során. Azonban a a padlórobotok programozását csak a válaszadók 6%-a említette és csak egyharmada hallott a padlórobotokról. A technológiai kompetenciák és az algoritmikus gondolkodás fejlesztésére vonatkozóan a fő akadályozó tényező az óvodapedagógusok nem megfelelő félkészültsége, szükség lenne ilyen irányú képzésekre.
Nuevos registros de especies exóticas en el centro de Argentina
Authors: Juárez Martín
Published: August 2024

Resumen: Se presentan nuevas citas documentadas para tres especies exóticas en el centro de Argentina: Cotula coronopifolia L. (Asteraceae) y Lycopsis arvensis L. (Boraginaceae) en el sur de la provincia de Santa Fe, y Spergularia marina (L.) Besser (Caryophyllaceae) en el sur de la provincia de Córdoba, ampliando el rango de distribución respectivo de cada una, y constituyéndose en taxones novedosos para las floras provinciales respectivas.
Estrategia de Extensión público-privada para mejorar la sustentabilidad de la producción lechera en empresas familiares
Authors: Gimenez Gustavo Daniel , Frana Bisang Emanuel Adrián , Sgubin Valeria Gisel , Bassi Andrés Zenón , Biga Pablo , Marini Pablo Roberto
Published: August 2024

La producción lechera se basa en empresas familiares, donde el productor es responsable de la gestión, aunque no realice el ordeño propiamente dicho. La complejidad del sistema en sus interacciones internas y con su entorno aporta causas para la disminución anual del número de lecherías; por ello requiere que los productores lecheros adquieran diversidad de competencias para abordar una problemática heterogénea. El objetivo fue aplicar una estrategia de extensión público-privada, para abordar aspectos condicionantes para la sustentabilidad de la lechería. Se trabajó a partir de octubre de 2019 en 15 lecherías de la cuenca sur de Santa Fe, situada en la región pampeana argentina, un área de clima templado bajo régimen monzónico de precipitaciones. Las condiciones edáficas presentan suelos con horizontes argílicos, texturas francas y contenido medio de materia orgánica. Se adoptó una estrategia de investigación-acción participativa, relevando los problemas presentes en la muestra; a partir de grillas para priorizarlos, se determinó un cronograma de abordaje. Esta metodología permitió organizar contenidos, abordar los conflictos cotidianos que afectan al productor y proponer líneas de trabajo sobre una variedad de medios, herramientas, audiencias y capacitadores. El resultado fue la creación de una red en la que interactuaron investigación-extensión-productor. Entrenada en el abordaje de problemas variados y comunes en las empresas lecheras, se articularon herramientas (escuela de oficios y reentrenamientos, Ateneo de jóvenes) y medios (capacitaciones presenciales y virtuales, teóricas y prácticas, comunicaciones a través de redes sociales, visitas). Esta estrategia de aplicación factible depende de la participación y compromiso por parte del productor y sus colaboradores, la posterior aplicación práctica de los conocimientos aprendidos y la constante actualización de temas demandados. Si es aprehendida, puede ser una estrategia de apoyo para las lecherías regionales.
Geografía de la interculturalidad crítica en la educación
Authors: Cea Jesús Martín
Published: August 2024

El artículo busca profundizar conceptualmente la relación entre tres elementos fundamentales: migración norte-sur, interculturalidad crítica y educación. Para ello se utiliza una metodología que permita, por un lado, problematizar el dinamismo existente entre estos agentes y la territorialidad física y abstracta que abordan; entendiendo por esto la integración en un marco jurídico y espacial. Y, por otro lado, evidenciar por qué existen grados de desigualdad en el acceso educativo de los diversos grupos migrantes y nacionales, revisar qué factores configuran esta desigualdad y responder a cómo los distintos tipos de financiamiento educativo –municipal/publico, particular subvencionado y particular– están relacionados cuantitativamente con el nivel socioeconómico del grupo migrante. Para ello, se emplea una técnica de análisis histórico que demuestra de fondo el funcionamiento de políticas de Estado que, en diversos periodos, han demostrado una lógica separatista, eurocéntrica y homogeneizante.
REVITALIZING DIGITAL-BASED BASIC EDUCATION IN AN EFFORT TO STRENGTHEN STUDENTS' CRITICAL AND CREATIVE THINKING IN THE PANCASILA STUDENT PROFILE PROGRAM AT MADRASAH IBTIDAIYAH
Authors: Noptario  , Ade Tinofa Nelva , Khoirotun Nisa Ani , Abdullah Faisal , Nazri bin Nordin Ts. Saiful
Published: August 2024

In the digital era, basic education needs to be revitalized to be renewable and in line with the times. One of the efforts that can be made is to utilize digital technology in learning. The Pancasila student profile program is project-based and can stimulate students to think critically and creatively. However, conventional learning is still found, so it is important to revitalize learning to provide novelty and improve learning. This study aims to reveal revitalization in basic education from conventional to digital-based learning to increase students' critical and creative thinking. This research uses a qualitative research approach with a Field Research research method. Data collection techniques in this study used interviews. Interviews were conducted with the principal, class teachers, and students. Research sources were selected through a purposive sampling technique. The data analysis technique used in this study uses thematic analysis theory to understand the data, compile codes, and look for themes. The location of this research is SDN Wijilan Kulonprogo Yogyakarta. Revitalization of digital-based learning is carried out by providing training to teachers, preparing supporting facilities and infrastructure and controlling and evaluating. Conventional learning needs to be revitalized because it only focuses on the teacher and makes students less active in learning, so the term digitization in learning emerged. Digitalization in learning can positively impact and make students think critically and creatively because it has advantages such as learning being more varied, students being more active in participating in learning, helping students improve their technological skills, and diverse learning resources. Teachers in the Pancasila student profile program strongly feel these advantages, as they can make students think critically and creatively.
THE USE OF FORMATIVE EVALUATION IN THE DEVELOPMENT OF SPATIAL BUILDINGS FOR ELEMENTARY SCHOOL STUDENTS BASED ON AUGMENTED REALITY
Authors: Sapta Andy , Nisa Uliya Khoirun
Published: August 2024

Learning media for elementary school students is an important tool that has developed in line with technological advances. Therefore, this study aims to evaluate learning media development on building space materials using Augmented Reality (AR) technology. Formative evaluation consists of initial analysis and stages. In addition, this study used 15 SDIT students, Alam Nurul Islam and Yogyakarta. The questionnaires distributed were related to the respondents' attitudes and responses. The results showed that students reacted positively to the development of AR learning media, and validation from experts obtained a feasibility percentage of 85.34% with valid criteria. Meanwhile, student responses expressed a sense of pleasure when the teacher explained the use of AR learning media. Mathematics material is easy to understand because geometry objects are realized as 3D objects through AR learning media. In addition, students are more active in learning by using AR learning media.
Estereotipos de género como predictores de sexismo hostil y benevolente en hombres y mujeres heterosexuales
Authors: Ávila Toscano Jose Hernando , De La Rosa Ibáñez Gisell , Hernández Chang Emilio Ariel , Navarro Barreto Abigail , Blanquicet Genes Rosaura
Published: August 2024

Los estereotipos de género asignan rasgos a hombres y mujeres generando segregación social y se relacionan con actitudes sexistas, que subvaloran la mujer mediante hostilidad manifiesta o aparente benevolencia. Los objetivos de este estudio fueron identificar estereotipos de género y manifestaciones de Sexismo Hostil y Benevolente en hombres y mujeres heterosexuales, y determinar si las creencias estereotípicas junto con las características demográficas predicen el tipo de sexismo. Mediante diseño transversal predictivo se evaluó a 475 personas (62.3% mujeres, 33.7% hombres), cumpliendo el análisis con la muestra general y con hombres y mujeres por separado usando modelos de regresión lineal. Se identificaron dos formas estereotípicas, a) Rasgos y características de superioridad masculina, b) Dominancia masculina; ambas predicen el Sexismo Benevolente, pero los estereotipos superioridad masculina demuestran mayor explicación de la variable (R2=.39, f2=.63>.35, 1-?=1.0), que los basados en dominancia del varón (R2=14, f2=.16>.15, 1-?=1.0). El Sexismo Hostil también es predicho por el primer grupo de estereotipos (R2= 41, f2=.69, 1-?=1.0). Entre los hombres, ambos estereotipos predicen las formas sexistas y en las mujeres el efecto de estereotipos de dominación masculina es reducido. Los estereotipos que asumen superioridad de los hombres (independencia, inteligencia, liderazgo, etc.) son los principales predictores de actitudes sexistas.
Alteraciones afectivo-comportamentales, acoso escolar y rendimiento académico en una población pediátrica: Salud mental y experiencia escolar
Authors: Agudelo Hernández Felipe , Guapacha Montoya Marcela , Delgado Reyes Andrés Camilo
Published: August 2024

Objetivo: Describir las alteraciones afectivas y comportamentales relacionadas con la experiencia escolar en población estudiantil de colegios públicos en Caldas-Colombia. Materiales y métodos: Estudio descriptivo, observacional de corte transversal, en individuos entre los 4 y 17 años. Se realizó durante el segundo semestre del año 2018 en 17 colegios públicos de las ciudades de Manizales y Aranzazu, en el departamento de Caldas, Colombia. Con el instrumento Child Behavior Checklist 4-18 (CBCL/4-18), se realizó medición de alteraciones afectivo-comportamentales, y la experiencia escolar se determinó con el rendimiento académico, el acoso escolar y el tiempo de juego. Resultados: La muestra estuvo constituida por 1533 niños. Se encontró que el 18,2% de los niños tenía problemas académicos, un 15,3% asistía a clases especiales y un 28.9% repitieron cursos; se evidenció que los niños que hacen menos tareas tiene una media de percentil más alta en comparación con los niños que hacen más o igual las tareas, siendo esta relación estadísticamente significativa con p menor de 0.05. En las asignaturas que mostraron peor rendimiento fueron matemáticas y lenguaje, además se encontró una relación estadísticamente significativa entre el rendimiento académico en las asignaturas principales y las alteraciones en los dominios de CBCL. Los percentiles para los síndromes del CBCL son mayores en los niños con acoso escolar. Conclusiones: Se encontró una importante frecuencia de síntomas internalizantes y externalizantes en la población estudiantil, además de alteraciones en la experiencia escolar, evidenciando asociaciones entre estas entidades.
FEZÂ’İL-İ BEYTÜ’L-MUKADDES’TE YER ALAN BAZI HALK İNANIŞLARINA DAİR SÖYLEMLER
Authors: Kara Serdal
Published: August 2024

Çalışmamız 17. yüzyılda Hıfzî tarafından kaleme alınan Fezâ’il-i Beytü’l-Mukaddes adlı eserde yer alan bazı halk inanışlarına dair söylemler üzerinedir. İncelemeye esas aldığımız Fezâ’il-i Beytü’l-Mukaddes’te yer alan halk inanışlarına dair söylemlerin din, kültür, coğrafya ve zamana bağlı olarak yeniden şekillendiği görülmektedir. Bu söylemlerden dünyanın şekli, duruşu ve mesafesine dair söylemlerin daha çok mitolojik unsurlar taşıdığı, ancak dünyanın sonuna dair söylemlerin dinsel olduğu görülebilmektedir. Pınar, ırmak, rüzgâr gibi dünya yaşamının vazgeçilmezi olan kaynakların oluşumları yarı mitolojik yarı dinsel yaklaşımla açıklanırken bazı kaynak suların beslenme şekli sadece dinsel söylemle açıklanmaktadır. Ayrıca bazı dinsel inançlardan dilsel söylemler geliştirilirken bazı nesnelerin tespit edilen zıt özelliklerinden de söylem geliştirilmektedir. Çalışmamızda ilk olarak Fezâ’il-i Beytü’l-Mukaddes hakkında kısa bir bilgi verilmekte daha sonra metinde tespit edilen halk inanışları ve bunlara dair yaklaşımlarımız yer almaktadır. Son olarak elde ettiğimiz bulguların değerlendirildiği Sonuç bölümüne yer verilmektedir.
TRT TÜRK HALK MÜZİĞİ REPERTUVARINDA YER ALAN OYUN HAVASI FORMUNDAKİ ESERLERİN BAĞLAMA İCRASI İÇİN ETÜT OLARAK DEĞERLENDİRİLMESİ
Authors: Güler Emirhan
Published: August 2024

Türk halk müziği, köklü tarihsel geçmişi, müzikal zenginliği ve geniş repertuarıyla, önemli bir müzik türü olarak kabul edilmektedir. Zengin repertuvar ve müzikal yapısı gerek teorik anlamda müziği öğrenmek isteyenlere gerek icracılara zengin bir kaynak olmaktadır. Bağlama da bu zengin kaynaktan oldukça faydalanmaktadır. Bu araştırma, TRT Türk halk müziği repertuvarı oyun havası formundaki eserlerden bağlama için etüt üretme üzerine odaklanmaktadır. Nitel araştırma yöntemleriyle yürütülen bu çalışmada, doküman analizi modeli kullanılmıştır. Araştırmada TRT Türk halk müziği repertuvarı 27 sıra numaralı Cirit Havası adlı eser örnek olarak alınmıştır. Bu eserden toplam 5 motiften 7 adet etüt türetilmiştir. Bu etütler, bağlama icrasını öğrenmek isteyenlerin parmak pozisyonlarını, yöresel tavırları, temel icra tekniklerini (süsleme, legato, vb.), hızlı ve teknik çalmayı geliştirmeyi amaçlamaktadır. Araştırmanın sonucunda, parmak baskısı, Ankara tavrının gelişimi, çeşitli pozisyon kombinasyonları, süsleme, legato (çarpma, çekme) tekniklerinin gelişimi, hızlı ve teknik çalmanın gelişimine yönelik etütler üretilmiştir.
ÖĞRETMEN ADAYLARINA YÖNELİK ÜST-DÜZEY DÜŞÜNME BECERİLERİ DEĞERLENDİRME ÖLÇEĞİ’NİN TÜRKÇEYE UYARLANMASI
Authors: Kaya Suat , Kurt Abdülkadir , Safalı Serdar , Balı Onur
Published: August 2024

Bu çalışmada Üst Düzey Düşünme Becerileri Değerlendirme Ölçeği’nin Türkiye koşullarında geçerlik ve güvenirliğinin incelenmesi amaçlanmıştır. Ölçeğin uyarlama sürecinde ileri çeviri yöntemi kullanılmıştır. Tarama yöntemi ile gerçekleştirilen bu çalışmanın örneklemini 819 öğretmen adayı oluşturmuştur. Veriler hem yüz yüze hem de çevrimiçi bir form kullanılarak toplanmıştır. Elde edilen veriler, SPSS 21.0 ve AMOS 21 programlarından yararlanılarak, açımlayıcı faktör analizi ve doğrulayıcı faktör analizi ile analiz edilmiştir. Araştırma sonucunda, öğretmen adaylarının üst-düzey düşünme becerilerini ölçmek için kullanılabilecek geçerli ve güvenilir bir ölçme aracı elde edilmiştir. Özgün ölçek, 4 faktör ve bu faktörlere ait 14 alt boyuttan oluşurken, Türkçe’ye uyarlama çalışması 4 faktörle sonuçlanmıştır. Bu bağlamda, gelecekteki çalışmaların daha büyük ve daha heterojen bir örneklemi kapsayacak şekilde planlanması önerilmiştir.
The commuting graph of a solvable 𝐴-group
Authors: Carleton Rachel , Lewis Mark L.
Published: August 2024

Let 𝐺 be a finite group.
Recall that an 𝐴-group is a group whose Sylow subgroups are all abelian.
In this paper, we investigate the upper bound on the diameter of the commuting graph of a solvable 𝐴-group.
Assuming that the commuting graph is connected, we show when the derived length of 𝐺 is 2, the diameter of the commuting graph will be at most 4.
In the general case, we show that the diameter of the commuting graph will be at most 6.
In both cases, examples are provided to show that the upper bound of the commuting graph cannot be improved.
Effects of E-learning Technologies on Librarians’ Sustainable Competence Development and Smart Library Services: Empirical Evidence from 244 Universities’ Librarians
Authors: Shahzad Khurram , Ahmad Khan Shakeel
Published: August 2024

The purpose of the study was to identify the effects of e-learning technologies on librarians’ sustainable competence development and smart library services. This study used a quantitative research design for addressing the objectives. The population consisted of librarians from the public and private sector universities (n = 244) of Pakistan. The data were analyzed by using Smart PLS. E-learning technologies was the independent variable while sustainable competence development and smart library services were dependent variables that further consisted of various constructs and items. A significant impact of e-learning technologies was found on all the sub-constructs of sustainable competence development and smart library services. Findings revealed that e-learning technologies turn librarians into skilled assets and innovative sustainable smart library services are implemented.
Constructing a prognostic model for colon cancer patients on basis of coagulation genes enriched in cancer-associated fibroblasts to guide personalized immunotherapy
Authors: Gao Rui , Zhou Qing , Hu Shangshang , Qin Jian , Xiao Qianni , Pan Yuqin , Sun Huiling , Chen Xiaoxiang
Published: August 2024

Objectives

Colon cancer is a global health challenge. This research is designed to build a prognostic model that can personalize the guidance of immunotherapy among colon cancer patients.

Methods

Coagulation-associated prognostic genes which were subsequently integrated into a Least Absolute Shrinkage and Selection Operator algorithm for constructing a prognostic model were identified with the univariate Cox analyses. The potential of coagulation-related risk score (CRRS) in prognosis and immunotherapy outcomes was rigorously assessed. Finally, the cellular origin of genes in the CRRS model was explored with single-cell RNA-seq data, and the biological functions of core genes were further confirmed by cell function experiments.

Results

Our findings showed the CRRS model usefully classified patients into high-risk and low-risk groups. High-risk patients exhibited worse total survival. A nomogram was subsequently devised, enabling quantitative survival prediction by incorporating CRRS, age, sex, and TNM stage. Moreover, the CRRS model predicted the extent of cancer-associated fibroblasts (CAFs) infiltration. The analysis further indicated diminished immune responsiveness in high-risk patients, and single-cell data analysis pinpointed TIMP1+ CAF as a potential contributor to cancer progression.

Conclusions

The CRRS model can be adopted as a prognostic device for colon cancer patients and low-risk patients are more suitable for treatment with immune checkpoint inhibitors. TIMP1 secreted by CAF can promote the malignant progression of colon cancer.
The case of the disappearing energy: potential energies in concentration gradients
Authors: Hansen Lee D. , Woodfield Brian F. , Tolley H. Dennis
Published: August 2024

This paper reviews observations on processes involving concentration gradients to show that (1) Concentration gradients can do external work during discharge if the system is arranged in a manner that requires it. (2) Work has to be done on the system (i.e. energy has to be added) to create a concentration gradient. (3) Concentration gradients can spontaneously discharge with no change in energy except interaction energy. These three observations are significant since, together, these observations demonstrate an apparent violation of the law of conservation of energy which is resolved by proposing that a probability field is a common element for all concentration gradients. This paper thus introduces two new concepts into thermodynamics: (1) Many spontaneous processes occur because of an increase in probability, not because of a decrease in the energy state of the system. (2) Concentration gradients coincide with a probability field and a constraint-dependent and temperature-dependent potential energy.
A sawtooth constitutive model describing strain hardening and multiple cracking of ECC under uniaxial tension
Authors: Li Lingyu , Chen Hongkang , Yu Hongfa , Ma Haiyan , Fan Haotian , Chen Xiaoqing , Gao Yuning
Published: August 2024

By collecting engineered cementitious composite (ECC) uniaxial tensile experimental research data, aiming at the multiple cracking characteristics of the strain hardening stage of the ECC stress–strain curve, a theoretical model describing the constitutive relationship of the ECC uniaxial tensile stress–strain – the multiple cracking sawtooth model – is proposed. Several model parameters were obtained with the fitting analysis of many ECC uniaxial tensile stress–strain curves. The application conditions and influencing factors of the three-order multi-crack “sawtooth” model of polyvinyl alcohol (PVA)-ECC and polyethylene (PE)-ECC and the four-order multi-crack “sawtooth” model of PVA-ECC are studied. The result shows that the higher the fiber reinforcement index, the better the tensile properties of ECC. The fiber reinforcement index is linearly correlated with the initial crack stress and ultimate tensile stress of PVA-ECC and with the ultimate tensile stress and ultimate tensile strain of PE-ECC. The characteristic points of PVA-ECC in the multi-crack cracking stage are as follows: the greater the initial cracking strain, the smaller the ultimate tensile strain, showing an exponential correlation; The greater the initial cracking stress is, the greater the ultimate tensile stress is, and the two are linearly correlated.
The Symbolic Significance of the Sacrifice of Thanksgiving
Authors: Him Ko Ming
Published: August 2024

According to Leviticus 7:12–15, the sacrifice of thanksgiving involved three kinds of unleavened bread (Lev 7:12), and prohibited anyone from leaving any of its flesh until morning (Lev 7:15). This article proposes that this dual requirement was intended to provide a symbolic link to the Passover meal (Exod 12:8–10), which acknowledged God’s salvation of his people from bondage and slavery. This symbolic significance is confirmed through an examination of the use of the term »the sacrifice of thanksgiving« in the Psalter, in which the thanksgiving offering usually serves as a response to God’s rescue from distress and as an expression of praise for God’s salvation. This comparison aids our understanding of the symbolic significance of the thanksgiving offering in relation to the remembrance of the Exodus event.
JAVIER MILEI AND MANAGERIAL POPULISM IN ARGENTINA: “THE SUCCESSFUL ENTREPRENEUR AS A SOCIAL BENEFACTOR”
Authors: Del Pino Díaz David
Published: August 2024

Introduction: Javier Milei, leader of La Libertad Avanza (LLA), has become the first president in history to define himself as a liberal libertarian. Mieli’s leadership is marked by his media projection as a political outsider capable of creating an antagonistic divide between the virtuous people and the corrupt establishment. This study aims to identify and analyze the characteristics of the phenomenon known as managerial populism in the Argentine president, Javier Milei, based on three significant interventions: 1)his first speech as President of Argentina on December 10, 2023; 2) the speech delivered at the World Economic Forum in Davos on January 17, 2024; and 3) the address at the Conservative Political Action Conference (CPAC) in Washington on February 25, 2024. Methodology: A qualitative approach will be undertaken using Critical Discourse Analysis (CDA). This methodology Will allow us to move beyond a formalistic study of language, connecting our discourse analysis with the growing phenomenon of managerial populism. Results: At this point, we will demonstrate the three pillars upon which Milei’s managerial populism rests: a) the construction of a virtuous people in opposition to the parasitic establishment; b) the notion that social justice is neither just nor social; and c) the defense of free-market capitalism, identifying entrepreneurs as social benefactors. Conclusions: This study demonstrates that Milei’s political objective is the construction of a popular ideology based on entrepreneurial elements, positioning the economic entrepreneur as a social benefactor.
DUDUNEY, Gavin; HOCHLY, Nicky; PEGRUM, Mark. Letramentos digitais.
Authors: Jeimes de Oliveira Paiva Francisco , Maria Pereira Lima Ana
Published: August 2024

Entre poucas obras, no campo dos estudos das linguagens e das tecnologias no Brasil, o livro Letramentos digitais - traduzido pelo editor Marcos Marcionilo – traz inúmeras contribuições para a aprendizagem linguística mediada por novas habilidades e novas estratégias de como se trabalhar pedagogicamente não só os conceitos-chave das teorias, mas também a aplicação/integração de pressupostos teóricos às práticas de ensino de línguas e tecnologias atualmente; conectando professores e alunos, possibilitando-os não apenas assimilar os aportes teóricos mencionados, fazer com que os professores, sobretudo da educação básica possam se apropriar de uma taxonomia e de uma explanação reflexiva acerca dos letramentos digitais.
CLEC5A Promotes Neuronal Pyroptosis in Rat Spinal Cord Injury Models by Interacting with TREM1 and Elevating NLRC4 Expression
Authors: Tan Yonghong , Wang Qiong , Guo Yubing , Zhang Na , Xu Yingyi , Bai Xue , Liu Jianhua , Bi Xiaobao
Published: August 2024

Pyroptosis, an inflammatory programmed cell death, has recently been found to play an important role in spinal cord injury (SCI). C-type lectin domain family 5 member A (CLEC5A), triggering receptor expressed on myeloid cells 1 (TREM1), and NLR-family CARD-containing protein 4 (NLRC4) have been reported to be associated with neuronal pyroptosis, but few studies have clarified their functions and regulatory mechanisms in SCI. In this study, CLEC5A, TREM1, and NLRC4 were highly expressed in lidocaine-induced SCI rat models, and their knockdown alleviated lidocaine-induced SCI. The elevation of pyroptosis-related indicators LDH, ASC, GSDMD-N, IL-18, caspase-1, and IL-1β levels in SCI rats was attenuated after silencing of CLEC5A, TREM1, or NLRC4. Lidocaine-induced decrease in cell viability and the elevation in cell death were partly reversed after CLEC5A, TREM1, or NLRC4 silencing. Lidocaine-mediated effects on the levels of LDH, ASC, GSDMD-N, IL-18, caspase-1, and IL-1β in lidocaine-induced PC12 cells were weakened by downregulating CLEC5A, TREM1, or NLRC4. CLEC5A could interact with TREM1 to mediate NLRC4 expression, thus accelerating neuronal pyroptosis, ultimately leading to SCI exacerbation. In conclusions, CLEC5A interacted with TREM1 to increase NLRC4 expression, thus promoting neuronal pyroptosis in rat SCI models, providing new insights into the role of neuronal pyroptosis in SCI.
The Courage to Ask: Primary Formation of Civic Capacity and the Transformation of Civic Engagement
Authors: Meyers Peter Alexander
Published: August 2024

Report on The Civic Inquirer’s experimental collaboration at Riverside School in Princeton, New Jersey, to test civic inquiry as an integrating factor in the elementary curriculum, together with theoretical groundwork for a revised conception of “civic engagement.” To engage with the entire report, please see the Supplementary Materials.
Un análisis sintáctico de las irregularidades flexivas en futuro y condicional
Authors: Fábregas Antonio
Published: August 2024

El objetivo de este trabajo es el de explicar las irregularidades flexivas en futuro y condicional a través de un análisis nanosintáctico en el que la irregularidad surge de la rivalidad entre exponentes que compiten para materializar el mismo espacio sintáctico. El análisis propone que los verbos irregulares en estas formas almacenan un exponente que lexicaliza parte del material funcional del área del modo; estos exponentes, cuando están presentes, se usan también en modo imperativo, lo cual explica que los verbos irregulares en imperativo también lo sean en futuro y condicional.
Examination of the Relationship Between Stress Coping and Problem Solving Skills of Physical Education Teachers
Authors: Denktaş Mehmet , Gözen İlhan , Şimşek Şeyma Elif , Çufadar Nizamettin Ulaş
Published: August 2024

This study aimed to investigate the relationship between coping with stress and problem-solving abilities among physical education teachers. The research sample comprised 64 female and 89 male physical education teachers, totaling 153 individuals, employed in schools under the Ministry of National Education in Mardin. Data collection instruments included a personal information form developed by the researcher, the Coping with Stress Scale developed by Türküm (2002), and the Problem Solving Inventory developed by Heppner and Peterson (1982) and adapted into Turkish by Şahin, Şahin, and Heppner (1993). Statistical analyses involved testing for variance and homogeneity, employing independent t-tests for pairwise comparisons, One-Way ANOVA for multiple comparisons, and conducting Correlate analysis to determine relationships. Results revealed no significant differences in mean scores for coping with stress or problem-solving skills among physical education teachers based on gender, school type, or years of service in the profession. However, a positive low-level relationship was identified between the coping with stress scores and problem-solving scores of the physical education teachers. In summary, the study revealed notably high mean scores for both coping with stress and problem-solving skills among physical education teachers, suggesting their adeptness at managing stressors and addressing challenges effectively. Additionally, it is postulated that physical education teachers who exhibit effective stress coping mechanisms are also proficient in resolving encountered problems.
Trump vs Biden: Análisis de sentimientos de las publicaciones en español realizada en Twitter en tres Estados de la Unión en las Elecciones Presidenciales del 2020
Authors: Del Castillo Collazo Nelson , Macías Herrera Rosa María
Published: August 2024

Las tecnologías digitales han cobrado gran relevancia dentro de la vida política en los Estados Unidos de América, un ejemplo es el uso de la red social Twitter en las elecciones presidenciales que se realizaron en noviembre del 2020 en ese país. El objetivo del presente trabajo es realizar el análisis de las publicaciones en Twitter de los individuos que publicaron en español en los Estados de la Florida, California y Texas relacionado con los candidatos Donald Trump y Joe Biden y describir el comportamiento de estos hacia los candidatos en las semanas previas a las elecciones presidenciales del 2020. Se muestra, entre otros aspectos, la variación de la carga sentimental diaria en el periodo estudiado. Para el presente trabajo se tomaron los tweets publicados entre los días 7 de septiembre del 2020 y el 2 de noviembre del mismo a˜no. Se obtuvieron resultados que indican el predominio de sentimientos positivos hacia el presidente Donald Trump en los Estados de la Florida y Texas mientras que en el Estado de California el predominio es hacia el candidato Joe Biden. Se hace una valoración del sentimiento de los individuos que publicaron en Twitter relacionados con las fórmulas vicepresidenciales de ambos candidatos.
Determining Payback Period and Comparing Two Small-Scale Vertical Axis Wind Turbines Installed at the Top of Residential Buildings
Authors: Saleh Yousif Abed Saleh , Austin Miguel Chen , Carpino Cristina , Turhan Cihan
Published: August 2024

In recent years, residential buildings have seen a notable increase in energy consumption. To address this, it is crucial for researchers to invest in renewable energy technologies, aiming to develop highly sustainable and nearly-zero energy buildings. Many countries are started to commit to this goal, seeking to phase out fossil fuels due to their harmful environmental effects. Wind energy stands out as a promising renewable resource, especially in areas with strong wind patterns. This study focuses on a case in Karaburun, Izmir province, Türkiye, where annual wind speeds range from 6 to 8 m/s and evaluates the performance of two types of small-scale Vertical Axis Wind Turbines (VAWTs) in reducing energy consumption in a three-story residential building, along with associated costs. Utilizing advanced simulation tools like ANSYS Fluent and DesignBuilder Software, the study examines Ice-Wind VAWTs and Savonius VAWTs. The findings reveal that installing 15 Ice-Wind VAWTs on the building's roof can reduce energy consumption by approximately 22.5%, with each turbine costing about $2000 and a payback period of around 14.57 years. Conversely, using 15 Savonius VAWTs can reduce energy consumption by 36%, with each turbine costing about $2300 and a payback period of around 8.93 years. These results indicate that the Savonius turbine offers a faster return on investment compared to the Ice-Wind turbine under the specified conditions. Overall, this study highlights the significant benefits and cost implications of integrating renewable energy solutions like VAWTs into residential buildings.