bluuebunny/crossref_metadata_2025 huggingface dataset:
Estimating the response time of a data-intensive computing environment
Authors: Gorbunova Anastasiya , Vishnevsky Vladimir
Published: September 2022

Introduction: The amount of digital data is constantly growing as well as the need for its storage and processing for various purposes. To conduct data analysis, high-performance computing environments associated with parallelization methods, and, accordingly, data-intensive applications are used. The lack of quality tools for evaluating the effectiveness of the process of parallel data processing or tasks leads to excessive allocation of resources. Purpose: To develop mathematical models of data-intensive computing environments and methods for their performance analysis, i.e., for estimating the average system response time based on the data on system performance at the level of subtask solving. Results: We present a mathematical model of a parallel computing system in the form of a queueing system with parallel query processing on various architectures, including non-Poisson input flow and non-exponential service times. As a method for analyzing the average response time, we use a combination of simulation modeling with one of the machine learning methods (artificial neural networks). The effectiveness of the method is confirmed by numerical experiments and depends neither on the type of input flow, nor on the type of distribution of query service times, nor on the number of servers in the nodes of the system. The approximation error of the average response time does not exceed 10%, which makes it possible to optimize the generally accepted resource allocation, significantly reducing the amount of the resources. Practical relevance: The presented models and the method of their analysis can be used for efficient planning and allocation of resources for data-intensive systems.
Search for EEG signal patterns in simulating phobic anxiety disorder situations in a VR environment
Authors: Tychkov Alexander , Chernyhov Denis , Churakov Petr , Yuldashev Zafar , Bofanova Natalia , Alimuradov Alan , Gorbunov Valeriy , Zolotarev Raslan , Nikitin Mihail
Published: September 2022

Introduction: Effective and prompt formulation of diagnostic conclusions about the presence of anxiety-phobic disorders requires the improvement of existing and the development of new methods for diagnosing and treating patients, including the use of virtual reality technology. Purpose: To analyze a reaction of an individual to a stimulus that triggers a fear response to virtual reality scenes (height exposure). To identify electroencephalographic (EEG) signal markers related to the level of anxiety and virtual reality environment susceptibility of an individual. Methods: A group of nine conditionally healthy males aged 23 to 26 years old who reported neither history of somatic symptoms nor organic brain disorders was formed to conduct the research. The immersion into virtual reality was accompanied by the registration of EEG signals and subsequent completion of a self-assessment questionnaire by the subjects. Results: The state of rest (a reference value) and the state of high emotional stress experience (at the height of a skyscraper) in the virtual reality environment were compared. The results obtained allow to make a conclusion that the simulated situation of being at a height causes a decrease in the indices of alpha, theta, beta rhythms, and an increase in the delta rhythm index of the EEG signal relative to the state of rest in various subjects, regardless of the intensity of fear manifestation. Practical relevance: The conducted research is among the pioneering studies in assessing the effect of virtual reality technologies on human phobic anxiety state. Some objective electrophysiological markers related to the level of anxiety were determined to confirm the presence of patterns in the functional state of the cerebral cortex with a sense of anxiety in individuals immersed in a virtual reality environment.
Features of Hymnographic Work in the 16th Century: Sources of Hymns to St. Alexander Svirsky
Authors: Островский Павел Валентинович
Published: September 2022

Статья посвящена рассмотрению источников и принципов построения текстов службы прп. Александру Свирскому, написанной в середине XVI в. одним неизвестным гимнографом. Кто он, компилятор или песнотворец, труд которого заслуживает внимания? В статье для каждого элемента службы указываются выявленные источники. Ф. Г. Спасский устанавливает три источника, к которым обращался автор при составлении службы св. Александру Свирскому. Это службы прп. Афанасию Афонскому, прп. Сергию Радонежскому и прп. Варлааму Хутынскому. В ходе более детального изучения текста нам удалось выявить ещё 13 источников. Поскольку св. Александр прославлен в чине преподобного, гимнограф обращается только к службам в честь преподобных. Также в статье подробно описываются способы составления песнопений. Первый способ - заимствование, выделяется прямое и адаптированное заимствование. Второй способ - дополнения заимствованного текста авторскими вставками. Третий способ - «нанизывание бус». Четвёртый способ - создание сложных конструкций из разных текстов. Пятый способ - использование только отдельных выражений и мотивов источника. Статья подводит к выводу о том, что за очевидной на первый взгляд компиляцией скрывается не механическое соединение текстов, а сложная и заслуживающая внимания работа гимнографа.

The article is devoted to the consideration of the sources and principles of constructing the texts of the service of St. Alexander Svirsky, written in the middle of the 16th century by one unknown hymnographer. Who is he, a compiler or a songwriter whose work deserves attention? The article identifies identified sources for each element of service, and details how the chants are composed. The first way is borrowing, direct and adapted borrowing is highlighted. The second way is to supplement the borrowed text with author’s inserts. The third way is «threading beads». The fourth way is to create complex constructions from different texts. The fifth way is to use only certain expressions or motives of the source. The article concludes that the compilation-based work of a hymnographer is complex and noteworthy.
Biblical Allusions about Human in the F. I. Tyutchev Poetry
Authors: Палий Сергей Александрович
Published: September 2022

В данной статье рассмотрены аллюзии Ф. И. Тютчева к Библии, касающиеся таких тем, как любовь в браке, любовь к друзьям, ответственность за служение перед людьми, образы порочности людей, необходимого обращения к Богу, смирения, покаяния. Автор анализирует фрагменты лирики Тютчева с опорой на труды исследователей творчества поэта и толкования библейских отрывков, которые являются маркерами отсылок, и приходит к выводу, что нравственное учение в поэзии мысли Фёдора Ивановича раскрывается во многих ярких образах в соответствии с учением Православной Церкви. Таким образом, поэт выполняет свою высшую миссию человека творчества: возвещает людям в доступной для них форме истины христианства и побуждает их к духовному деланию.

F. I. Tyutchev’s allusions to the Bible, concerning such topics as love in marriage, love for friends, responsibility for serving before people, images of people’s depravity, the necessary appeal to God, humility, and repentance are discussed in this article. The author analyzes fragments of Tyutchev’s lyrics based on the works of researchers of the poet’s work and the interpretation of biblical passages, which are markers of references, and concludes that the moral teaching in the poetry of Fyodor Ivanovich’s thought is revealed in many vivid images in accordance with the teachings of the Orthodox Church. Thus, the poet fulfills his highest mission of a person of creativity: he proclaims to people the truths of Christianity in an accessible form for them and encourages them to spiritual work.
Saudi Arabia. New challenges to the kingdom
Authors: Vasiliev Alexey
Published: September 2022

The deployment of armed forces of the US and its allies on the territory of Saudi Arabia in 1990 and their war against Iraq in 1991 strengthened American dominance in the region and at the same time revealed previously concealed internal contradictions in Saudi society. A divide between the pro-monarchy and anti-Saudi movements became evident. It resulted in an ideological struggle between former allies - the Wahhabis and the Muslim Brothers - inside and outside the kingdom. The Islamist discourse of the Brothers and Sahwa movement (a sort of hybrid of Wahhabism and Muslim Brotherhood ideology) manifested itself in questioning the legitimacy of the Saudi rule and promoting a general anti-American attitude. Those contradictions gave birth to Al-Qaeda, which declared a global jihad against the West and the monarchies of the Persian Gulf.
The September 11, 2001 attacks in New York gave Washington an excuse to invade Afghanistan and then, after a successful blitzkrieg there, encouraged the US to begin a war in Iraq under the fake pretext of Iraqi plans to develop all kinds of weapons of mass destruction. Consequences for the Saudi government included the strengthening of Sunni - Shiite contradictions inside the kingdom and in the region as well as an explosion of terrorism inside Saudi Arabia.
After the establishment of the Shiite majority government in Iraq, the Sunni - Shiite contradictions have turned into a cold war between Saudi Arabia and Iran. This situation aggravated the instability in the Middle East and precluded potential compromises.
Stability analysis of laminated beams with Kelvin–Voigt damping and strong time delay
Authors: Nonato C.A. , Raposo C.A. , Feng B. , Ramos A.J.A.
Published: September 2022

In this paper we consider a model of laminated beams combining viscoelastic damping and strong time-delayed damping. The global well-posedness is proved by using the theory of semigroups of linear operators. We prove the lack of exponential stability when the speed wave propagations are not equal. In fact, we show in this situation, that the system goes to zero polynomially with rate [Formula: see text]. On the other hand, by constructing some suitable multipliers, we establish that the energy decays exponentially provided the equal-speed wave propagations hold.
Detect – Debunk – Communicate: Combating Misinformation with More Realistic NLP
Authors: Gurevych Iryna
Published: September 2022

Dealing with misinformation is a grand challenge of the information society directed at equipping computer users with effective tools for identifying and debunking misinformation. Current Natural Language Processing (NLP) including fact-checking research fails to meet the requirements of real-life scenarios. In this talk, we show why previous work on fact-checking has not yet led to truly useful tools for managing misinformation, and discuss our ongoing work on more realistic solutions. NLP systems are expensive in terms of financial cost, computation, and manpower needed to create data for the learning process. With that in mind, we are pursuing research on detection of emerging misinformation topics to focus human attention on the most harmful, novel examples. We further compare the capabilities of automatic, NLP-based approaches to what human fact checkers actually do, uncovering critical research directions for the future. To edify false beliefs, we are collaborating with cognitive scientists and psychologists to automatically detect and respond to attitudes of vaccine hesitancy, encouraging anti-vaxxers to change their minds with effective communication strategies.
Abstract Argumentation with Conditional Preferences
Authors: Bernreiter Michael , Dvořák Wolfgang , Woltran Stefan
Published: September 2022

In this paper, we study conditional preferences in abstract argumentation by introducing a new generalization of Dung-style argumentation frameworks (AFs) called Conditional Preference-based AFs (CPAFs). Each subset of arguments in a CPAF can be associated with its own preference relation. This generalizes existing approaches for preference-handling in abstract argumentation, and allows us to reason about conditional preferences in a general way. We conduct a principle-based analysis of CPAFs and compare them to related generalizations of AFs. Specifically, we highlight similarities and differences to Modgil’s Extended AFs and show that our formalism can capture Value-based AFs.
How Complex Is the Strong Admissibility Semantics for Abstract Dialectical Frameworks?
Authors: Keshavarzi Zafarghandi Atefeh , Dvořák Wolfgang , Verbrugge Rineke , Verheij Bart
Published: September 2022

Abstract dialectical frameworks (ADFs) have been introduced as a formalism for modeling and evaluating argumentation allowing general logical satisfaction conditions. Different criteria used to settle the acceptance of arguments are called semantics. Semantics of ADFs have so far mainly been defined based on the concept of admissibility. Recently, the notion of strong admissibility has been introduced for ADFs. In the current work we study the computational complexity of the following reasoning tasks under strong admissibility semantics. We address 1. the credulous/skeptical decision problem; 2. the verification problem; 3. the strong justification problem; and 4. the problem of finding a smallest witness of strong justification of a queried argument.
Just a Matter of Perspective
Authors: König Matthias , Rapberger Anna , Ulbricht Markus
Published: September 2022

Many structured argumentation approaches proceed by constructing a Dung-style argumentation framework (AF) corresponding to a given knowledge base. While a main strength of AFs is their simplicity, instantiating a knowledge base oftentimes requires exponentially many arguments or additional functions in order to establish the connection. In this paper we make use of more expressive argumentation formalisms. We provide several novel translations by utilizing claim-augmented AFs (CAFs) and AFs with collective attacks (SETAFs). We use these frameworks to translate assumption-based argumentation (ABA) frameworks as well as logic programs (LPs) into the realm of graph-based argumentation.
Fluidised bed agglomeration of strawberry powder mix obtained for spray drying
Authors: Castaño-Pelaez Hader , Cortés Rodríguez Misael , Gil Jesús , López Gloria , Ortega-Toro Rodrigo
Published: September 2022

BACKGROUND:

The microencapsulation process using spray drying (SD) represents an effective alternative in protecting the active components present in strawberries. However, microcapsules of strawberry powder mixtures present problems of instantanisation and flowability; an aspect that can be solved by agglomeration of the particles.

OBJECTIVE:

The aim of this study was to evaluate the influence of the fluidised bed agglomeration process on the flow, instantaneity and antioxidant properties of strawberry powder obtained by SD.

METHODS:

The response surface methodology (RSM) was used with a centred composite central design (α=1), considering the factors: fluidisation air temperature (50-70°C), time (30-50 min) and atomisation air pressure of the binder agent (1-2 bar).

RESULTS:

An increase in particle size was observed in the agglomeration process; the agglomerated particles showed a decrease in wetting time, the agglomerates of strawberry powder mixtures presented excellent instantanisation and fluidity, solving the problems identified in the microcapsules obtained by SD.

CONCLUSIONS:

Although the moisture and aw levels were increased in the agglomeration process, the values are within the microbiological and physicochemical food safety range; moreover, there was no effect on the phenol content and antioxidant capacity. The experimental optimisation achieved desirability of 68.4%, the optimum conditions being 70°C, 30 min and 1 bar.
Tratamento da infeção por Helicobacter pylori nos cuidados de saúde primários: um trabalho de melhoria da qualidade
Authors:   USF Atlântico Norte, Cabral Estela , Costa Ângela ,   USF Senhora de Vagos, Oliveira Dinamene ,   UCSP Águeda V, Lopes Maria João ,   USF Leme, Garcia W. Sofia ,   UCSP Anadia III
Published: September 2022

Introdução: Vários regimes de antibioterapia têm sido propostos para tratamento da infeção por Helicobater pylori (Hp) e a escolha de terapêutica adequada deve basear-se nas resistências locais aos antibióticos, com recurso a terapia quádrupla. Pretende-se com este trabalho melhorar a qualidade da prescrição para tratamento das infeções por Hp, de acordo com a NOC, recomendações clínicas mais recentes e perfis de resistência em Portugal. Materiais e Métodos: Este é um trabalho de melhoria de qualidade técnico-científica com dois momentos de avaliação interna, em cinco unidades da Zona Centro. Foram considerados todos os utentes com diagnóstico de infeção por Hp num período de três meses antes e após uma breve intervenção sobre as orientações mais atuais no tratamento do Hp. Os dados foram recolhidos do MIM@UF® e SClínico® e tratados em Microsoft Excel® 2016. Resultados: Na avaliação obtiveram-se 68 utentes com diagnóstico positivo para Hp. Destes, 65 receberam tratamento para um total de 46% (n=30) com tratamento adequado. No período pós-intervenção foram avaliados 65 utentes com diagnóstico de infeção por Hp. Destes, 62 receberam tratamento para um total de 71% (n=44) com tratamento adequado. Discussão: A intervenção traduziu-se numa melhoria da escolha de terapêutica de primeira linha. Houve uma diminuição na escolha da terapêutica tripla, assim como no erro de prescrição. Conclusão: Este trabalho evidencia como a intervenção formativa junto dos médicos poderá contribuir para a melhoria da qualidade da prescrição para tratamento da infeção por Hp.
O estranho desaparecimento do dispositivo intrauterino de cobre: relato de caso
Authors:   USF do Minho, ACES Cávado I, Gonçalves Ana Rita Moreira Coutinho , Oliveira Ana Catarina Dias ,   USF do Minho, ACES Cávado I, Domingues Inês Gonçalo ,   USF do Minho, ACES Cávado I, Ferreira Carina ,   USF do Minho, ACES Cávado I, Caetano José Rui Seabra ,   USF do Minho, ACES Cávado I, Fonte António Pedro ,   USF do Minho, ACES Cávado I, Machado Helena ,   USF do Minho, ACES Cávado I
Published: September 2022

Introdução: Este caso descreve um dos efeitos adversos possíveis da contraceção intrauterina, nomeadamente do dispositivo intrauterino de cobre (Cu-DIU), e explora o procedimento a realizar no âmbito dos cuidados de saúde primários (CSP). Descrição do caso: Em outubro de 2019, a utente optou por Cu-DIU e realizou uma ecografia pré-procedimento (sem alterações). Em fevereiro de 2020 foi colocado um Cu-DIU nos CSP, o que ocorreu sem intercorrências; pediu-se ecografia de controlo. Devido ao contexto pandémico, a utente não a realizou e manteve método de barreira. Em março de 2021, a ecografia realizada não identificou o Cu-DIU. A utente negou perceção de expulsão do dispositivo ou outros sintomas. Na observação não foram detetados os fios do Cu-DIU, pelo que se solicitou radiografia abdominal. Realizada em abril de 2021, esta mostrava o dispositivo “na zona média da escavação pélvica, em posição oblíqua de perfil”. Uma nova ecografia ginecológica identificou o DIU na “escavação pélvica, em topografia extrauterina, lateralizado à esquerda do útero”. A utente foi encaminhada para consulta hospitalar urgente e notificou-se a ocorrência à Unidade de Vigilância de Produtos de Saúde (UVPS), da Direção de Produtos de Saúde (DPS) do INFARMED. Em consulta de ginecologia, em junho de 2021, a utente ficou inscrita para laparoscopia para remoção de Cu-DIU e salpingectomia bilateral para contraceção definitiva. Comentário: Este caso alerta para a importância da avaliação ecográfica, após colocação de dispositivos intrauterinos, para confirmação da sua localização e garantia, por um lado, da eficácia do método e, por outro, da rápida deteção de complicações. Pretendeu-se ainda fazer uma breve revisão do procedimento a adotar em casos semelhantes: realização de exame físico e exames complementares de diagnóstico, participação às autoridades competentes e referenciação precoce à ginecologia para a rápida resolução da situação.
2021 European guidelines on cardiovascular disease prevention: what is the news?
Authors:   Instituto de Investigaciones Biomédicas Sant Pau, Brotons Carlos
Published: September 2022

2021 European guidelines on cardiovascular disease prevention: what is the news?
Sisters Are Doing It for Each Other
Authors: Herbison Victoria
Published: September 2022

Shakespeare’s play, The Taming of the Shrew, has faced harsh criticism for its sexist portrayal of women and depictions of abuse. Yet, modern adaptations of the play continue to be produced. Gil Junger’s 1999 teen romantic comedy adaptation of The Taming of the Shrew, titled 10 Things I Hate About You, appears to challenge the play’s problematic themes by developing the relationship between sisters Katherine and Bianca beyond the play’s strict, sexist notion that the ideal woman should be obedient and submissive to their husband. In doing so, the film enfranchises the sisters beyond the play’s binary characterization of women as good or bad. Instead turning them into more complex and human characters. Though the film also introduces Kat and Bianca as rebellious and obedient respectively, scenes in which the sisters discuss their romantic relationships as well as address and resolve their own conflicts allow them complex character development as both women and sisters. As such, the film subverts the play’s gender binaries by prioritizing the development of a loving relationship between sisters in favour of heterosexual romance, thus suggesting that sisterhood is a theme worth contemplation and exploration. The characterizations of Kat and Bianca in 10 Things I Hate About You encourages its audience to reject sexist and limiting understandings of women as depicted in The Taming of the Shrew by illustrating the complexities of young women and idealizing the support and love found within sisterhood.
Promises Made or Promises Kept?
Authors: Selinger Matthew James
Published: September 2022

Reverberating effects of the Indian Residential School system's legacy continue to threaten Indigenous languages. In establishing the Truth and Reconciliation Commission (TRC), all levels of Canadian governments and civil society received 94 ‘Calls to Action’ in coming to terms with Canada’s colonial past and rooted inequities. Some of these Calls stress the need to revive and preserve Indigenous languages. Statistics prove the existence of this decline. Government commissions and Indigenous governing bodies warn of the implications of neglecting this unique crisis facing Indigenous communities nationwide. With the introduction of the Indigenous Languages Act in 2016, the federal government appears ready to commit to the TRC’s recommendations on Indigenous language revitalization. However, what this research finds are that Canadian provincial and federal governments have much room for improvement. This paper assesses the details of legislation and compares inconsistencies with promises made and the results of government inaction. Therefore, contrary to Canada’s optimism, the steps it takes to revitalize Indigenous languages are inadequate and require significant rethinking to prove truly effective.
Winding Routes and Precarious Switchbacks
Authors: Krug-MacLeod Alana Michelle
Published: September 2022

Silk Road developments increased interconnectivity through trade, but little is written about the resulting effect on food diversity. I used three methodologically, geographically and temporally diverse studies examining aspects of food during the Silk Road period to identify key factors affecting botanical and dietary food diversification in Central Asia during the first millennium. Archaeological and historical data from a study of Tashbulak (800-1100) revealed narrowing of genetic diversity accompanying cultivation, but also broadening of food options through trade and human interventions that created new plant varieties. A comparative study of the medieval period (500-1300) using human remains and published isotopic (δ13C and δ15N) records of urban and non-urban consumers in the Turkmenistan-Uzbekistan-Kazakhstan region showed the Silk Road fostered greater overall food diversity than occurred in the Iron Age and early first millennium (1300 BCE- 600 CE). It also showed that, although during the medieval period enhanced trade opportunities facilitated a food-diversity trend, the positive movement was eroded by urban, insular agricultural communities with reified social structures. Foodways analysis of recipe books revealed that during the Mongol period (1200-1400), multi-cultural interaction enhanced dietary diversity, whereas changing power dynamics, tradition, and sense of place countered the trend. The Silk Road was not a unilinear path toward dietary diversity, but rather, a series of winding routes beset with potentially precarious switchbacks. Travelling back along the first millennium Silk Road uncovers critical turning points that can inform global food diversity approaches in the 21st century.
A consolidação do patriarcado no Brasil: a origem das desigualdades entre homens e mulheres
Authors: Andrade Letícia Ésther de
Published: September 2022

Nos primórdios da sociedade, as populações eram nômades e a descendência era atribuída somente às mães. Com a passagem do nomadismo para o sedentarismo, as populações descobriram a participação masculina na reprodução. Posteriormente, surgiu a cultura de entregar os bens dos homens falecidos para seus descendentes e, para que isto fosse possível, os homens passaram a exigir de suas esposas fidelidade. Ao restringir a mulher no âmbito doméstico, garantindo sua fidelidade para fins de descendência patrimonial, também se passa a exigir da mulher habilidades próprias e específicas para este ambiente. Esse processo promoveu a mudança da sociedade matriarcal para a sociedade patriarcal e, por consequência, a desigualdade entre os gêneros. Tendo em vista este cenário, o presente artigo, tem como questão norteadora: De que forma o patriarcado interferiu no processo de desigualdade entre homens e mulheres brasileiros? Para responder a essa pergunta, foi realizada uma revisão teórica, apresentando, inicialmente, uma explicação de como o patriarcado surgiu no mundo; posteriormente, como a cultura patriarcal foi trazida para o Brasil, tendo como objetivo compreender como se deu o processo de desigualdades entre homens e mulheres brasileiras. A partir dos resultados, concluímos que essa cultura baseada em desigualdade foi trazida para o Brasil no período colonial, sendo reproduzida de geração em geração. Nessa relação desigual entre homens e mulheres, a mulher deixou em segundo plano seus desejos e sonhos, cabendo a ela um papel social restrito, abaixo dos homens.
Chagas disease / COVID-19 comorbidity. An advantage to chagasic patients?
Authors:   Investigaciones Parasitológicas “J.F. Torrealba”, Facultad de Ciencias, Universidad de Los Andes, Mérida, 5101, Venezuela, Anez Néstor Oswaldo , Crisante Gladys , Salmen Siham , Paredes Cesar , Parada Henry ,   Instituto de Inmunología, Facultad de Medicina, Universidad de Los Andes, Mérida,  5101, Venezuela,   Hospital Central de Sabaneta, Ministerio de Salud, Barinas, Venezuela,   Unidad de Car- diología, Hospital “Luis Razetti”, Ministerio de Salud, Barinas, Venezuela
Published: September 2022

Introduction. Chagas’s disease a neglected and debilitating tropical illness, caused by Trypanosoma cruzi-infection, afflicts millions of people in most Latin-American countries. In the same region, frequent and severe viral infection cases have been reported due to SARS-CoV-2, the causative agent of COVID-19, deemed as the worst global pandemic in the 21st century. Objective. To investigate the Chagas disease-COVID-19-relationship, and the comorbidity effect on chagasic patients living in communities where SARS-CoV-2 have circulated during the last two years causing severe cases and deaths. Material and methods. Randomly selected chagasic patients (N=50) from rural localities of western Venezuela, where COVID-19 has occurred, were evaluated in order to know whether they had suffered SARS-CoV-2- infection. COVID-infected chagasic patients were clinically compared with non-chagasic individuals (N=22) who had suffered the viruses in the same localities. Results. SARS-CoV-2-infection caused significantly less aggressive effects in chagasic patients than in non-chagasic patients, evidenced by the short-lasting scarce mild symptoms and the attenuated clinical profile (p<0.05), without further complications. Comparison revealed COVID-19 detection in 10% of chagasic patients, showing all of them mild clinical pattern and few symptoms, while non-chagasic COVID-infected control individuals, showed 45% and 13% severe and fatal cases, respectively. Conclusion. Chagasic patients suffering from COVID-19 comorbidity seem to express a robust immune response (Th1/Th2/Th17), which associated with anti-T. cruzi-glycoproteins circulating antibodies, directed to certain SARS-CoV-2glycoproteins (membrane/spike), may induce a short lasting and milder clinical profile. More investigations in populations where Chagas disease is endemic, is recommended.
Physical and Mental Health Problems in Post-COVID Patients
Authors:   Astana Medical University, Orazbekova Zhanar , Orazova Galiya ,   Astana Medical University
Published: September 2022

This review analyzed the results of 8 meta-analyses and systematic reviews that assessed the quality of life of patients who have had COVID-19.In patients with acute COVID-19 who were in intensive care units, quality of life is significantly lower than in patients with a long course of coronovirus infection. Decreases in HRQoL in COVID-19 survivors are most commonly associated with long-term manifestations of the disease, such as fatigue, shortness of breath, anosmia, sleep disturbances, and worsen mental health.There are significant differences in HRQoL among COVID-19 survivors based on gender, age, disease severity, and study country. COVID-19 affects the HRQoL of women, patients with severe comorbidities, and patients over the age of 60, especially in patients from low-income countries. The long-term impact of COVID-19 on patients' HRQoL is still in the early stages of investigation.The results of this review led us to conclude that the EQ-5D-5L is an effective tool for assessing HRQoL in post-COVID-19 patients.Key words: coronovirus infection, COVID-19, health-related quality of life, post-coronavirus disease.
Health Indicators of the Population of Khromtau District of Aktobe Region
Authors:   Khromtau central district hospital, Rybakova Vera , Berdesheva Gulshara ,   West Kazakhstan State Medical University named after M. Ospanov
Published: September 2022

The study presents the dynamics and characteristics of demographic indicators, as well as health indicators of the population of the Khromtau district of the Aktobe region in the period 2019-2020, in the aspect of studying the impact on the statistical indicators of the SARS-COVID-19 pandemic.The purpose of the study was to assess the territorial features of primary health care indicators in Khromtau district of Aktobe region for 2021-2020.Research methods included elements of descriptive statistics. The general demographic indicators, the results of screening studies, the performance indicators of the Disease Management Program, the dynamics of morbidity and mortality rates of the population due to socially determined and monitored diseases were analyzed.Results. In 2020, there is a decrease in primary morbidity by 29.4% (8 807.5 0/0000 (2019 – 12 447.10/0000 )). Primary morbidity in the district decreased due to the child population – 10 703.70/0000 (2019 year - 21 533.70/0000 ).This can be explained in general by a decrease in the number of people seeking medical care for chronic diseases during the pandemic. However, the mortality figures for individual nosologies show an increase in rates, which in turn may also be due to late seeking medical attention Mortality from tuberculosis in 2020 was 1.60/0000 (2019 - 1.30/0000 ), from diseases of the circulatory system - 28.50/0000 (2019 - 15.30/0000 ), from diseases of the gastrointestinal tract for 2020 - 39.50/0000 (2019 - 15.30/0000 ); from diseases of the urinary system for 2020 - 37.30/0000 (2019 - 32.80/0000 ); as a result of injuries and accidents for 21.90/0000 (2019 - 6.60/0000 ).Conclusions. Despite the decrease in primary morbidity, there has been an increase in mortality, which most likely represents the consequences of the pandemic, including the restriction of the population's access to medical care, and in the future, primary health care efforts should be directed to active prevention and detection of chronic diseases.Keywords: primary health care, population health indicators, socially significant diseases, morbidity, mortality.
Human Resource Development in Managing the Creative Economy during the COVID-19 Pandemic in the Community of Tafure and Sulamadaha Village, Ternate City
Authors: Nurlaila Nurlaila
Published: September 2022

This study aims to provide an in-depth overview of the application of the creative economy during the COVID-19 pandemic to increase economic income. Human Management Resources in an organization are not just administrative but lead to developing the potential of human resources to be creative and innovative. A creative economy is an economic concept combining something with an element of creativity by combining ideas, ideas, and knowledge from human resources as a production factor. The condition of the COVID-19  pandemic is very unsettling for the community. Therefore it requires skills and the desire of business actors to develop a creative economy. The research uses a descriptive qualitative approach with respondents, samples from the Tafure community and the Sulamadaha community, respectively, as many as four people who have a business with key informants from the local community who have had a business for 8 and 10 years. Retrieval data in the form of observations and interviews with eight people consisting of 6 field informants and two key informants. The data collection technique uses triangulation in which researchers compare information from the field with information and data from informants, both field informants and key informants, with conditions in the local area. Research data analysis is inductive; some data and information are obtained and then developed into a hypothesis. The COVID-19 pandemic has made the economic life of a business very impactful on people’s financial income. Tafure community business actors have implemented creative economy human resource development through participation in education and training activities.
EFEITOS DA FOTOBIOMODULAÇÃO ASSOCIADO AO EXERCÍCIO FÍSICO NA SAÚDE E DESEMPENHO HUMANO
Authors: Pereira De Brito Alcides , Mendes Rodrigues Eliane
Published: September 2022

Os mecanismos da fotobiomodulação (FBM) são baseados na promoção de adenosina trifosfato (ATP) mitocondrial, aumentando o fornecimento de energia, promovendo uma recuperação mais eficaz dos tecidos e tem sido indicado para tratar lesões musculares, melhorar a recuperação muscular após o exercício, mostrando melhores resultados do que os métodos convencionais. Objetivo do presente estudo foi analisar o efeito da FBM associado ao exercício físico em relação a saúde e desempenho humano. Este estudo trata-se de uma revisão bibliográfica integrativa e baseia-se em citações de trabalhos anteriormente publicados sobre FBM associado ao exercício físico, com o intuito de descrever a literatura em um questionamento científico qualitativo sobre o tema. Foram integralizados nos critérios da pesquisa 18 estudos pesquisados com utilizações de artigos científicos e dissertações nos bancos de dados como Scielo, Lilacs e Pubmed com uso de palavras-chaves: fotobiomodulação, terapia de luz de baixo nível, exercício físico, saúde. A análise dos estudos sobre FBM associado ao exercício físico na saúde e desempenho humano é um assunto que vem despertando um crescente interesse na comunidade científica, existindo fatores primordiais que podem ser desenvolvidos com a FBM associado ao exercício físico e utilizados dentro da reabilitação e desempenho com vertentes para adaptações neuromusculares como ativação e potência muscular e melhoras morfológicas. Dessa maneira, a partir da classificação, seleção e leitura de trabalhos científicos, evidenciou-se que a FBM associado ao exercício físico é mais uma alternativa capaz de proporcionar alterações significativas no desempenho e saúde humana.
Harnessing Monocytes for a Liposomal Rosiglitazone-Mediated Anti-Inflammatory Effect
Authors: Shvindelman Osnat , Nordling-David Mirjam M. , Grad Etty , Golomb Gershon
Published: September 2022

Rosiglitazone, an anti-diabetic drug used for treating type Ⅱ diabetes mellitus with known anti-inflammatory properties, was withdrawn from the European market. The United States Food and Drug Administration has restricted its use due to its severe cardiovascular adverse effects. We hypothesized that rosiglitazone could be repurposed to provide safe anti-inflammatory therapy. By encapsulating the drug in liposomes internalized preferentially by circulating monocytes, monocytes’ inhibition can be achieved while avoiding the inherent systemic side effects. Rosig-litazone was loaded into empty liposomes by an active loading method. The formulation (LipRosi) was developed with desirable physicochemical properties promoting preferential monocyte internalization via membrane surface negative charge. Appropriate physicochemical properties include nano-size, low polydispersity index (PDI), high drug loading capacity, high encapsulation yield, and shelf-life stability. Further, these liposomes exhibited time- and con-centration-dependent uptake in a murine monocyte/macrophage cell line (RAW264.7). In addi-tion, LipRosi was found to be significantly more effective in depleting monocytes than drug-free liposomes and free drugs in solution. A cytotoxic effect on smooth muscle cells was only ob-served at the highest concentration examined and after an extended exposure time. In vivo stud-ies in rats demonstrated a time-dependent uptake by intact circulating white blood cells (WBC), primarily monocytes. Administration of 20 mg/kg LipRosi, injected on two consecutive days, achieved a therapeutic window of monocyte depletion after 24 hr. Of note, only a dismal dispo-sition of the formulation was detected in the heart. Since monocytes play a central role in the progression of inflammatory related-disorders, LipRosi could be found therapeutic for multiple disorders.
Higher Values in Bangka Belitung Folklore and Its Contemporer Context
Authors: Asyraf Suryadin  , Tien Rostini  , Diana Anggraeni  , Nanda Saputra
Published: September 2022

This research finds out how far the noble values are contained in the Bangka Belitung folklores. These values are the result of the human mind reflection which will indirectly be revealed in folklore. Through the analysis of the noble value's description of each folklore, then it is simply sorted and observed which values are the most prominent. Qualitatively, there are 28 types of noble values with a total of 103 occurrences of noble values from the combination of the five Bangka Belitung folklores. The more dominant noble values are 20 social values, 11 hard work values, 10 compassion values, religious values, 8 culture and caring values. As for honesty and tenacity, they have 4 values. The noble values contained in the Bangka Folklore is relevant in the current state of individualism. The spirit of social care, hard work, compassion, and religious values persists in rural communities in Bangka Belitung.
Postoperative Outcome of Laparoscopic Appendicectomy- A Study of 100 Cases
Authors: Rashid Md Shoeb Ur , Begum Muslema , Chhanda Chhamita Sultana , Parveen Farzana , Daud AKM , Das Aparna
Published: September 2022

Background : An elegant, reliable procedure that can be easily performed is laparoscopic appendicectomy (LA). In patients with undiagnosed abdominal pain requiring more diagnostic investigations, as well as in patients with perforated appendicitis with or without intra-abdominal abscess, this procedure remain useful and safe.
Objective : To evaluate the postoperative outcome and complication in laparoscopic appendicectomy.
Methods : This prospective observational study was conducted at Rezia Taleb Hospital, Dhaka in Bangladesh. Total 100 cases were included in this study during the period of January 2018 to December 2019. Total 100 admitted uncomplicated acute appendicitis patients who underwent LA were enrolled in this study. Diagnosis is based on patient history (symptoms) and physical examination with an elevation of neutrophilic leukocytosis and raised CRP. In this study inclusion criteria of the cases were- Age <40 years, Alvarado Score 7 or more, Uncomplicated appendicitis, patients who underwent LA for appendicitis, both sexes. Exclusion criteria were - Incidental LA, patients with significant co-morbid medical conditions, patient unwilling to incorporate with the protocol, patients with psychiatric illness, and who lost to follow-up.
Results : Out of 100 patients, most of them 63(63%) were in age group <20 years. The mean age was 21.70±6.21 years. Majority 77(77%) were male and 23(23%) were female and male: female ratio was 3.3:1. Among the 100 respondents, majority 95(95%) presented with migratory right iliac fossa pain and 5 (5%) had early postoperative complication. Majority 95(95%) patient’s pain control occurred within1-2 days with NSAID. Out of 95 Uncomplicated patients; Length of Hospital stay was 1-2 days in 90(94.7%) and 3-4 days in 5(5.3%) cases.
Conclusion : This study showed that laparoscopic appendicectomy had found to be associated with shorter hospital stay, decreased postoperative pain and wound infection.
Northern International Medical College Journal Vol. 12 No.1 July 2020, Page 486-488
Capacidades dinámicas generadoras de valor agregado en las empresas agroindustriales de la provincia de El Oro.
Authors: Bustamante-Jumbo Silvana , Castillo-Cruz Genesis , Pacheco-Molina Andrés , Mora-Sanchez Norman
Published: September 2022

Las capacidades dinámicas en la actualidad permiten a las empresas adaptarse a las nuevas condiciones del mercado, por lo tanto, el presente trabajo tiene por objetivo establecer las capacidades dinámicas que conllevan a las empresas agroindustriales a generar valor agregado para potencializar el negocio y el crecimiento sostenible. La metodología aplicada es de enfoque cualitativo, por el método inductivo deductivo, donde se analizaron datos provenientes de seis empresas agroindustriales de la provincia de El Oro, donde se examinaron las variables capacidades dinámicas y valor agregado. Entre los principales hallazgos, se obtuvo como capacidad dinámica generadora de valor agregado a la de innovación, que al implementarla el principal aspecto que se consiguió fue el incremento de la productividad; en cuanto al beneficio que generó fue la reducción de la incertidumbre en la comercialización de los productos y detección de nuevas oportunidades en el mercado, además entre los factores que potencializaron la comercialización fueron: la calidad, precio y la gestión ambiental; de lo anteriormente expuesto, se concluyó que la CD de innovación a más de generar valor agregado ayudó al desarrollo económico y productivo de las organizaciones, puesto que al innovar facilita la generación de estrategias y ventajas competitivas.

Palabras Claves:

Capacidades dinámicas, empresas agroindustriales, valor agregado, innovación
El teletrabajo como tendencia de contratación post pandemia, ventajas y desventajas
Authors: Becerra-Sarmiento María , Revelo-Oña Renato
Published: September 2022

El propósito de esta investigación es determinar si las ventajas y desventajas del teletrabajo pueden incidir para que se convierta en una tendencia de contratación. Método. La investigación fue inductiva para analizar el teletrabajo y correlacional porque se analizó el teletrabajo ante la modalidad presencial; se aplicó una encuesta a 88 empresas públicas, privadas y Ongs, en las 4 regiones del Ecuador.  Resultados. Las mujeres superan en teletrabajo a los hombres; sin embargo, a los hombres les gustaría el teletrabajo más que a las mujeres; las empresas de servicios y comerciales aplicaron teletrabajo a más del 50% de sus colaboradores; las ventajas y desventajas del teletrabajo son iguales a nivel mundial. Discusión y conclusiones. En América Latina no existen normativas ni políticas claras para el teletrabajo, lo que genera desventajas que no son solucionadas por nadie.  Las empresas públicas, personas con niños pequeños, con discapacidad o quienes tengan trabajos distantes, son candidatos para ser teletrabajadores.  El teletrabajo es la nueva tendencia de contratación del siglo 21 que proporciona ahorro y efectividad, pero para tener éxito es necesario que sea aceptada o solicitada por el colaborador, más no impuesta por la empresa.
KAJIAN STILISTIKA KUMPULAN PUISI "EMBUSAN ANGINMU" KARYA ENNY HIDAJATI
Authors: Sari Rida Sariq , Hidajati Enny
Published: September 2022

Abstract : Enny Hidajati is a lecturer and poet from Palembang. Enny was brn in Ngawi , East Java, on August, 26 1971. Enny has her own style (stylistic) which is very beaulful from the point of view of life. The collectionof poem studied is entitled “Embusan Anginmu” the problem studied in this study is how thestylistic styleof thecollectionof poems “Embusan Anginmu” is and how the leical, rhyming and figurative elements are. Therefore, this study aims to reveal the stylistic stylein the collection of poems “Embusan Anginmu”. This research is a library research using descriptive method. Theresearcher will eamine the poems in Enny’s poetry collection entitled “Embusan Anginmu” to determine the  theme of each poem, then they will be grouped according to the predetermined theme. After than the researcher will choose one of each poem that has been determined according to their respectivethemes. Then the researcher will determine the elements in each poem, namely lexical elements, rhyme and figure of speech.

 

Keywords:Poem, Stylistic, LexicalElemen, Rhime, Figure, Of Speech, Embusan Anginmu, Enny Hidajati, Learning

 

Abstrak : Enny Hidajati merupakan seorang dosen sekaligus penyair yang berasal dari Palembang. Enny lahir di Ngawi Jawa Timur, pada tanggal 26 Agustus 1971. Enny memiliki gaya bahasa (stilistika) tersendiri yang sangat indah dalam sudut pandang kehidupan. Kumpulan puisi yang diteliti berjudul “Embusan Anginmu” masalah yang dikaji dalam penelitian ini adalah bagaimana gaya stilistika kumpulan puisi “Embusan Anginmu” dan bagaimana unsur leksikal, rima dan majasnya. Oleh karena itu,   penelitian ini bertujuan untuk mengungkap gaya stilistika dalam kumpulan puisi tersebut dan menentukan unsur leksikal, rima dan majas yang ada di dalam kumpulan puisi “Embusan Anginmu”. Penelitian ini berjenis penelitian perpustakaan dengan menggunakan metode deskripstif. Peneliti akan meneliti pisi-puisi yang ada didalam buku kumpulan puisi Enny yang berjudul “Embusan Anginmu”untuk menentukan tema pada tiap puisi, kemudian akan dikelompokkan sesuai dengan tema yang sudah ditentukan. Setelah itu peneliti akan memilih satu dari setiap puisi yang sudah ditentukan sesuai dengan temanya masing-masing. Kemudian peneliti akan menentukan unsur-unsur pada setiap puisi yakni unsur leksikal, rima dan majas.

 

Kata kunci: Puisi, Gaya Stlistika, Unsur Leksikal, Rima, Majas, Embusan Anginmu, Enny Hidajati,