bluuebunny/crossref_metadata_2025 huggingface dataset:
Materiales didácticos de filosofía helenística
Authors: García Peña Ignacio , García Castillo Pablo
Published: November 2020

En esta obra se recogen materiales muy diversos, que pretenden servir de complemento a la docencia de las asignaturas relacionadas con la filosofía helenística. El trabajo, fruto de un Proyecto de Innovación y Mejora Docente, supone la continuación de los Materiales didácticos de Historia de la Filosofía Antigua, conservando su estructura en lo fundamental: indicando objetivos y actividades y ofreciendo selecciones de textos, comentarios, definiciones de términos y repertorios bibliográficos. Empleamos la expresión «filosofía helenística» en un sentido más historiográfico que histórico, pues incluimos las escuelas de los denominados socráticos menores, cronológicamente anteriores a Aristóteles, y no separamos lo helenístico de lo romano. Antes bien, el hilo conductor de la obra lo conforman las distintas corrientes y escuelas, que en esta época se configuran y desarrollan de manera muy definida. Se trata, en cualquier caso, de un periodo fructífero e interesantísimo en la historia de la filosofía, cuya comprensión se pretende facilitar gracias al conjunto de herramientas que aquí se recogen.
Characterization of Burkholderia pseudomallei from spontaneous melioidosis in a Bornean orangutan
Authors: Testamenti Vincentius Arca , Surya Maryati , Saepuloh Uus , Iskandriati Diah , Tandang Maryos Vigouri , Kristina Lia , Wahyudi Aris Tri , Sajuthi Dondin , Santi Vivi Dwi , Patispathika Fiet Hayu , Wahyu Muhtadin , Nurcahyo Anton , Pamungkas Joko
Published: November 2020

Background and Aim: Melioidosis is a potentially fatal disease affecting humans and a wide range of animal species; it is often underdiagnosed and underreported in veterinary medicine in Indonesia. This study aimed to characterize morphological and molecular features of Burkholderia pseudomallei, the causative agent of melioidosis which caused the death of a Bornean orangutan.

Materials and Methods: Pulmonary abscess samples were cultured on several types of media, including Ashdown agar, Ashdown broth, and MacConkey agar. Type three secretion system orf 2 real-time polymerase chain reaction (PCR) and latex agglutination tests were performed to identify the bacteria. Morphological characteristics were compared to all previously published morphotypes. Subsequently, the bacteria were characterized by multilocus sequence typing (MLST) and Yersinia-like flagellum/Burkholderia thailandensis-like flagellum and chemotaxis PCR. The results of the genotyping were afterward compared to all genotypes from Southeast Asia.

Results: Multiple morphotypes of B. pseudomallei were perceived during the growth on Ashdown agar. Furthermore, it was identified by MLST that the Type I and Type II morphotypes observed in this study were clones of a single ST, ST54, which is predominantly found in humans and the environment in Malaysia and Thailand, although a very limited number of reports was published in association with animals. Moreover, the E-BURST analysis showed that the ST is grouped together with isolates from Southeast Asian countries, including Malaysia, Thailand, Singapore, and Cambodia. ST54 was predicted to be the founding genotype of several STs from those regions.

Conclusion: B. pseudomallei ST54 that caused the death of a Bornean orangutan has a distant genetic relationship with other STs which were previously reported in Indonesia, implying a vast genetic diversity in Indonesia that has not been discovered yet.
Effect of low oxygen tension on transcriptional factor OCT4 and SOX2 expression in New Zealand rabbit bone marrow-derived mesenchymal stem cells
Authors: Safitri Erma
Published: November 2020

Background and Aim: Octamer-binding transcription factor 4 (OCT4) and sex-determining region Y-box 2 (SOX2) are transcription factors whose functions are essential to maintain the pluripotency of embryonic stem cells. The purpose of this study was to derive stem cells for in vitro culture and to maintain their viability and pluripotency, with the goal to obtain a cell line for transplantation in patients with degenerative diseases or injuries. This research focused on examining the effect of low oxygen tension on the ability of bone marrow-derived mesenchymal stem cells (BM-MSCs) to express OCT4 and SOX2 in vitro.

Materials and Methods: BM-MSCs were obtained from femurs of 2000 to 3000 g New Zealand male rabbits. BM-MSCs were divided into three groups to test different culture conditions: A control group under hyperoxia condition (21% O2) and two treatment groups with low oxygen tension (1% and 3% O2). We characterized the BM-MSCs using flow cytometric measurement of cluster differentiation 44 (CD44) and cluster differentiation 90 (CD90) expression. The expression of OCT4 and SOX2 was measured by immunofluorescence staining after 48 h of incubation in chambers with normal or low oxygen tension with controlled internal atmosphere consisting of 95% N2, 5% CO2, and 1% O2 (T1) and 3% O2 (T2). We considered OCT4 and SOX2 as two markers of pluripotency induction. All immunofluorescence data were subjected to a post hoc normality Tukey's honestly significant difference test; all differences with p<5% were considered significant.

Results: BM-MSCs were positive for CD44 and CD90 expression after isolation. Oxygen tension culture conditions of 1% and 3% O2 led to OCT4 and SOX2 expression on culture days 2 and 4 (p<0.05), respectively, as compared to the hyperoxia condition (21% O2).

Conclusion: Based on the OCT4 and SOX2 immunofluorescence data, we conclude that the stem cells were pluripotent at low O2 tension (at 1% O2 on day 2 and at 3% O2 on day 4), whereas under 21% O2 the OCT4 and SOX2 were not expressed.
QUALIMETRIC ANALYSIS OF MISTAKEN ACTIONS OF THE CLIMBER DURING THE PASSING OF THE COMPETITIVE ROUTE
Authors: Kotchenko Juri Vasilievich
Published: November 2020

The article presents the results of studies devoted to the analysis of erroneous actionsof the climber at the time of passing the competitive route. During the three competitive seasonsof 2016–2018 the performances of women at major international tournaments in the disciplineof difficulty climbing were studied (n = 631). Studies have revealed the main errors made duringthe climbing, to classify them, to determine the signs of controlled and uncontrolled errors. It wasestablished that the controlled errors do not have a noticeable direct impact on the result, but havea negative impact on the main spatial and temporal characteristics of climbing.A fundamentally new method of quantitative assessment of technical and tactical errors hasbeen developed, based on the use of the time factor of erroneous actions. Calculations made usingthe new method that the average error rate for champions is 0.28 points, for prize-winners is 0.40,and for athletes taking a place below the 20th is 1.6 points. During the analysis of the collected data,the of connection with the result of the performance R = 0.81 was established and the nature of thedependence of this relationship was determined.The regression model is constructed, which allows to calculate the standard error value dependingon the length of the passed section and determine its location in the overall of the competitive process.The knowledge of the error value makes it possible to conduct a complete analysis of the sportsperformance, the lost part of the competitive as a result of the error and adjust the training processin order to minimize erroneous actions.
Some considerations on the use of space sound absorbers with next-generation materials reflecting COVID situations in Japan: additional sound absorption for post-pandemic challenges in indoor acoustic environments
Authors: Sakagami Kimihiro , Okuzono Takeshi
Published: November 2020

In this study, we first point out the possible acoustic problems associated with the post-pandemic operation of built environments. In particular, we focus on the problem of acoustic deficiency due to the lack of absorption. This deficiency, which is likely to be encountered in most enclosed spaces in a range of establishments, is due to the reduced number of audience members or users of the space as a result of social distancing. As one of the promising solutions to this problem, we introduce a sound absorption technique using three-dimensional (3D) space sound absorbers developed through our recent research projects. Significantly, the type of sound absorber proposed herein is made of materials that are especially suited to hygiene considerations. The materials are microperforated panels (MPPs) and permeable membranes (PMs), both of which are easily washable and sanitised. Furthermore, we point out that 3D-MPP or PM space absorbers possess the additional value of aesthetic designability.
Teachers as researchers: Reflecting on the challenges of research–practice partnerships between school and university in Chile
Authors: Guerrero-Hernández Gonzalo R. , Fernández-Ugalde Rocío A.
Published: November 2020

Teachers have tended to be underestimated as experts of their own practice and relegated to a technical role. In this context, action research appears as a form to legitimate teachers as active agents and producers of educational knowledge. This article aims to examine how a collaborative research–practice partnership between schools and universities in Chile fosters teachers’ role as researchers. It adopts a qualitative methodology based on thematic analysis of data collected from questionnaires and focus groups. In particular, it reports perceptions of in-service teacher researchers who conducted research projects between 2016 and 2017 as a part of a researcher–practitioner partnership strategy implemented by a university in Chile. The findings suggest that the partnerships were highly valued among teachers because the partnerships allowed them to develop pedagogical reflection towards the improvement of their practices and required particular awareness and recognition of roles and the relationships between practical and theoretical knowledge. Finally, possibilities for strengthening teachers’ role as researchers and collaborative research are presented at the end of the article.
A microestrutura de um dicionário semibilíngue como ferramenta para a aprendizagem de alemão como língua estrangeira
Authors: Domladovac Silva Carolina , De Almeida Azevedo Murakawa Clotilde
Published: November 2020

RESUMO: O presente artigo tem por objetivo analisar os componentes da microestrutura do Wahrig: dicionário semibilíngue para brasileiros - alemão (2011), a fim de verificar sua contribuição para a aprendizagem de língua estrangeira. Por meio da recolha de unidades lexicais relativas ao domínio da farmácia, bem como de seus respectivos verbetes, e consequentemente de sua microestrutura, pretende-se constatar tanto as características lexicográficas e/ ou terminográficas, quanto as características pedagógicas e/ ou didáticas do dicionário em questão. Fundamenta-se nas teorias da Lexicografia Pedagógica (DURAN, 2004; DURAN; XATARA, 2007), que busca atender às necessidades dos aprendizes de idiomas, e da Metalexicografia Pedagógica (DURAN; XATARA, 2006), cujo desenvolvimento é necessário para a adequação dos dicionários à especificidade e ao nível de conhecimento dos alunos de língua estrangeira. Por meio da análise de verbetes recolhidos com base em um tema cotidiano de uso, isto é, útil a aprendizes/ profissionais de diferentes níveis, pretende-se ainda reconhecer as características que possam contribuir ou não para a elaboração de um dicionário pedagógico.

PALAVRAS-CHAVE: Lexicografia Pedagógica. Metalexicografia Pedagógica. Dicionário semibilíngue. Definição.
Foreword
Authors: Guth Sarah
Published: November 2020

This collection of case studies could not come at a more auspicious time, and not only because of the global pandemic that is affecting all of our lives. Virtual exchange is often presented as an innovative approach to teaching and learning across cultures, but inherent in the word ‘innovative’ is the concept of something being ‘new’. As a practice, as well as a focus of research, different forms of virtual exchange have been around for over three decades. What is perhaps ‘new’ is the exponential growth of the field in the past five years, and the coming together of a community of practitioners, researchers, and funders who now place their different models under the umbrella term of ‘virtual exchange’.
Introduction
Authors: Helm Francesca , Beaven Ana
Published: November 2020

This volume brings together a series of case studies which illustrate how VE projects have been developed and implemented in a range of different settings. Most of the case studies presented were developed in the context of the Erasmus+VE project (2018-2020), a pilot project funded by the European Commission. The aims of the project are to offer young people in Europe and in Southern Mediterranean countries opportunities to engage in a meaningful cross-cultural experience, as part of their formal or non-formal education.
Virtual exchange: Romania and Hungary 100 years later
Authors: Cioltan-Drăghiciu Andra , Stanciu Daniela
Published: November 2020

The aim of this Virtual Exchange (VE) project was to bring together students from the Andrássy Gyula German speaking university (AUB) in Budapest, Hungary, and Lucian Blaga University in Sibiu (LBUS), Romania, in order for them to get to know their neighbors and reflect on the way the end of WWI is remembered 100 years later. In this case study, we discuss the way we conceived the three iterations of the VE (2018-2020), the challenges we faced on different levels, as well as the value of this teaching method for the academic field of history.
Task-enhanced virtual exchange between University of Sfax, Tunisia, and Hacettepe University, Turkey
Authors: Moalla Asma , Abid Nadia , Balaman Ufuk
Published: November 2020

This chapter presents a case study of an online task-enhanced Virtual Exchange (VE) project that involved 19 English students at Hacettepe University, Turkey, and 19 students of English at Sfax University, Tunisia. The objective behind the VE was to provide students with opportunities for intercultural and interactional development through the performance of collaborative intercultural tasks. At the end of the project, students’ performances were assessed and graded, and the project was evaluated by Tunisian students, by means of narratives. The case study concludes with recommendations to be taken into consideration for future VE projects.
Nauczyciel akademicki – pomiędzy autonomią, zaangażowaniem i nihilizmem
Authors: Kwieciński Zbigniew
Published: November 2020

Contemporary culture offers and constantly enriches many models of life, values, and consumption incentives. Pedagogy is also pluralistic today, rich in currents and trends. Teachers, including academics, face the unavoidable and constant choice between getting involved in the work with students and detachment and autonomy, or rather encouraging young people to choose their own identity and orientation, because all choices are equal. It is necessary to seek a common minimum of formal and material goals of upbringing. One of such formal purposes is that of independent judgment, i.e. the autonomy and the ability to think critically. Human is inseparable from the material; there is a dispute, however, about the components of this category. Recognition of the equality of all cultural discourses leads to nihilism with all its consequences.
O racjonalności dydaktyki jako przedmiotu nauczania i jako subdyscypliny pedagogicznej
Authors: Mieszalski Stefan
Published: November 2020

Within pedagogical sciences, didactics appears in at least two forms: as a subject taught in higher education and as one of branches of pedagogy. That is why in the field of didactics there is more than one type of rationality; they vary with respect to different purposes of two forms of didactics mentioned above. The main purpose of the article is to analyze some issues related to rationality present in both forms of didactics. In the context of the subject taught in universities, several issues are discussed, e.g. the issue of relationships between structure of didactic content and structure of teacher activities during the teaching process. With respect to didactics as one of the branches of pedagogy, Karl R. Popper’s standpoint is used to discuss the problem of asymmetrical relationships between verification and invalidation of prepositions in the field of didactics.
Comparing Engineering Properties of Small Diameter Pressuremeter Tests to Clegg Impact Hammer Tests in Cemented Coquina Base and Sandy Subgrades
Authors: Cosentino Paul J. , Misilo III Thaddeus J.
Published: November 2020

A comprehensive field testing program was undertaken to show that the small diameter pressuremeter (SDPMT) produces engineering data that compare well with the existing literature and Clegg Impact Hammer data. SDPMT tests were conducted using two SDPMT probe lengths (15- and 30-cm or 6- and 12-inch) and inflation techniques (incremental injection and continuous injection). Incremental tests required about 5 to 10 minutes to complete while continuous tests were completed within 1 minute. This device was successfully used in the drive pin hole used for nuclear density testing. Following a preliminary SDPMT equipment validation, 156 SDPMT tests and 96 Clegg Impact Hammer tests were performed in three sandy pavement subgrades and a cemented coquina base rock at four locations in Brevard County, Florida. SDPMT at-rest, initial stiffness, and limit pressures were evaluated using five statistical models. Good to excellent correlations were developed between the stiffness and limit pressure. Regression coefficients (R2) as high as 0.98 were found from SDPMT tests with incremental injection using the longer probe, indicating that these two variables are correlated. Comparisons between SDPMT stiffness and strength parameters and Clegg Impact Values (CIV) also produced strong correlations, with R2 values ranging from 0.75 to 0.90, indicating that CIVs are correlated to SDPMT strength and stiffness. These results indicate that SDPMT tests produce reliable strength and stiffness parameters in sandy subgrades and cemented coquina base materials common in Brevard County, Florida.
Oscillation-Based Connectivity Architecture Is Dominated by an Intrinsic Spatial Organization, Not Cognitive State or Frequency
Authors: Mostame Parham , Sadaghiani Sepideh
Published: November 2020

Functional connectivity of neural oscillations (oscillation-based FC) is thought to afford dynamic information exchange across task-relevant neural ensembles. Although oscillation-based FC is classically defined relative to a prestimulus baseline, giving rise to rapid, context-dependent changes in individual connections, studies of distributed spatial patterns show that oscillation-based FC is omnipresent, occurring even in the absence of explicit cognitive demands. Thus, the issue of whether oscillation-based FC is primarily shaped by cognitive state or is intrinsic in nature remains open. Accordingly, we sought to reconcile these observations by interrogating the ECoG recordings of 18 presurgical human patients (8 females) for state dependence of oscillation-based FC in five canonical frequency bands across an array of six task states. FC analysis of phase and amplitude coupling revealed a highly similar, largely state-invariant (i.e., intrinsic) spatial component across cognitive states. This spatial organization was shared across all frequency bands. Crucially, however, each band also exhibited temporally independent FC dynamics capable of supporting frequency-specific information exchange. In conclusion, the spatial organization of oscillation-based FC is largely stable over cognitive states (i.e., primarily intrinsic in nature) and shared across frequency bands. Together, our findings converge with previous observations of spatially invariant patterns of FC derived from extremely slow and aperiodic fluctuations in fMRI signals. Our observations indicate that “background” FC should be accounted for in conceptual frameworks of oscillation-based FC targeting task-related changes.

SIGNIFICANCE STATEMENTA fundamental property of neural activity is that it is periodic, enabling functional connectivity (FC) between distant regions through coupling of their oscillations. According to task-based studies, such oscillation-based FC is rapid and malleable to meet cognitive task demands. Studying distributed FC patterns instead of FC in a few individual connections, we found that oscillation-based FC is largely stable across various cognitive states and shares a common layout across oscillation frequencies. This stable spatial organization of FC in fast oscillatory brain signals parallels the known stability of fMRI-based intrinsic FC architecture. Despite the observed spatial state and frequency invariance, FC of individual connections was temporally independent between frequency bands, suggesting a putative mechanism for malleable frequency-specific FC to support cognitive tasks.
Manifestaciones Pedagógicas en los procesos de Formación Deportiva
Authors: Parra Klusmann Lina Marcela
Published: November 2020

El deporte y su práctica hacen parte de la cultura de un pueblo. A diario, las noticias sobre aspectos positivos y negativos del deporte hacen que este cobre un interés particular en la población en general. Las escuelas de formación deportiva se caracterizan por permitir el ingreso progresivo de los niños y jóvenes al deporte a través de unas etapas, fases o niveles; es decir, el niño que ingresa al deporte pasará por diferentes momentos de aprendizaje que le permitirán avanzar en una posible vida deportiva. En ese sentido, podría afirmarse que existe un proceso pedagógico. Pero es necesario preguntarse qué es un proceso pedagógico, cómo se puede evidenciar y qué manifestaciones pueden dar cuenta de la existencia de la pedagogía. A partir de lo anterior, La presente investigación busca develar las manifestaciones pedagógicas presentes en los procesos de las escuelas de formación deportiva del Instituto Municipal de Recreación y Deporte (imrd) de Chía, Colombia, de modo que haga posible la identificación de un marco de enseñanza-aprendizaje, en un espacio de educación extracurricular como lo es el deporte. Al realizar la investigación en un contexto natural, esta presenta una metodología de enfoque cualitativo de alcance descriptivo-interpretativo, con una perspectiva hermenéutica, al buscar el significado en las evidencias de las manifestaciones pedagógicas en las escuelas de formación deportiva del imrd.
Ciencia abierta y COVID 19
Authors: Camilo Alejandro Corchuelo Rodriguez
Published: November 2020

Curso para padres de Familia USTA – “ROCCA SECCA” - Módulo de herramientas para la investigación y la innovación: Descubrimientos de la ciencia, COVID 19, qué enfrentamos perspectiva y prospectiva desarrollada por la Dirección de Investigación e Innovación.
Effect of extractives on the physicochemical properties of biomass pellets: Comparison of pellets from extracted and non-extracted sycamore leaves
Authors: Liu Jianbiao , Cheng Weidong , Jiang Xuya , Khan Muhammad Usman , Zhang Qingfa , Cai Hongzhen
Published: November 2020

Physicochemical properties of biomass pellets were compared following their preparation from extracted and non-extracted sycamore leaves. The goal was to achieve high-quality biomass pellets. Batches of pellets were prepared at different moisture contents and pressure. The properties, including pellet density, diametric compressive strength, and combustion performance, were analyzed. Pellets produced from extracted leaves had higher pellet density (between 1125 and 1250 kg·m-3) compared to those made from non-extracted leaves. In addition, data of the combustion experiment showed more weight loss in extracted leaves’ pellets and a higher burning rate (9.54%·min-1) than that of non-extracted leaves’ pellets (8.47%·min-1). Also, the pellets made from extracted leaves could be ignited and burned easily compared to non-extracted leaves. However, the diametric compressive strength was not always higher in extracted leaves’ pellets compared to non-extracted. In general, it was concluded that extraction could increase the pellet density and improve combustion performance but did not fit the purpose to increase the diametric compressive strength. The analysis and conclusions can provide a reference for the production of high-quality biomass pellets.
Various Experimental factors behind the Missing Elements in PIXE Spectrum of Charnockite Matrix
Authors: Avupati A.V.S. Satyanarayana , M. Jagannadha Rao M. Jagannadha Rao
Published: November 2020

In the chemical characterization of charnokite is well investigated by using PIXE and other analytical techniques, but PIXE not given information about some of elements completely, because every technique including PIXE has proper limitations. To obtain the complete geochemical explanation of matrix charnockite composition, the experimental factors behind missing elements in PIXE at 3 MeV techniques with comparison must known and hence are used for the analysis of matrix compositions related to the earth materials like charnockite. In this study, the results obtained from PIXE compared with other analytical techniques and experimental factors of PIXE are discussed. By investigating the geochemical nature of complex charnockite material, the experimental factors which are related to the missing elements in this study of wide range of elements obtained from PIXE spectrum through the previous analytical techniques have been discussed.
Care of Pediatric Solid Organ Transplant Recipients: An Overview for Primary Care Providers
Authors: Katz Daphna T. , Torres Nicole S. , Chatani Brandon , Gonzalez Ivan A. , Chandar Jayanthi , Miloh Tamir , Rusconi Paolo , Garcia Jennifer
Published: November 2020

As the number of living pediatric solid organ transplant (SOT) recipients continues to grow, there is an increased likelihood that primary care providers (PCPs) will encounter pediatric SOT recipients in their practices. In addition, as end-stage organ failure is replaced with chronic medical conditions in transplant recipients, there is a need for a comprehensive approach to their management. PCPs can significantly enhance the care of immunosuppressed hosts by advising parents of safety considerations and avoiding adverse drug interactions. Together with subspecialty providers, PCPs are responsible for ensuring that appropriate vaccinations are given and can play an important role in the diagnosis of infections. Through early recognition of rejection and posttransplant complications, PCPs can minimize morbidity. Growth and development can be optimized through frequent assessments and timely referrals. Adherence to immunosuppressive regimens can be greatly improved through reinforcement at every encounter, particularly among adolescents. PCPs can also improve long-term outcomes by easing the transition of pediatric SOT recipients to adult providers. Although guidelines exist for the primary care management of adult SOT recipients, comprehensive guidance is lacking for pediatric providers. In this evidence-based overview, we outline the main issues affecting pediatric SOT recipients and provide guidance for PCPs regarding their management from the first encounter after the transplant to the main challenges that arise in childhood and adolescence. Overall, PCPs can and should use their expertise and serve as an additional layer of support in conjunction with the transplant center for families that are caring for a pediatric SOT recipient.
RESEARCHES ON BEHAVIOUR OF REGULATION WORKS LOCATED IN MORPHOLOGICALLY UNSTABLE RIVER BEDS
Authors: Sion Paul Vivian , Luca Mihail , Logigan Ilie , Avram Mihaela
Published: November 2020

The paper deals with the behaviour of geotextile regulation works on the dynamic action of floods in erodable river beds. Geotextiles have become an important component in the structure of river bed regulation and shore protection works. The dynamic action of floods, through liquid and solid flows, influences the stability and the resistance in time of geotextile constructions. The studies and researches were carried out on a sector of Moldova River between Soci and Pildeşti localities, on the territory of Iaşi and Neamţ counties. The researchers analysed the behaviour of geo-bagss made of polyester bags filled with local materials (generally sand and gravel) used for bottom sills, routing dikes and shore protection elements. The research results indicate a differentiated behaviour of geo-bagss according to their location (in water or on shore) and water action (dynamic or static). Water dynamic action has caused significant degradation of geo-bagss from bottom sills and routing dikes structures located in the river bed. Geo-bagss have low resistance to the alluvial material action (stone, trees) transported in the river bed during floods. The research highlighted the proper behaviour of geo-bagss during the river bed erosion phenomenon, when they moved and ensured the continuity of the bottom sills and their performance.
TOWARDS AN AUTOMATIC METEOROLOGICAL FORECAST VERIFICATION SYSTEM FOR THE STATE HYDROMETEOROLOGICAL SERVICE, REPUBLIC OF MOLDOVA
Authors: Pomaga Raluca , Birsan Marius-Victor , Rosca Ghennadii , Dabija Tatiana
Published: November 2020

This paper presents a user-friendly application developed for assessing the quality of the meteorological forecasts issued by the Moldavian State Hydrometeorological Service (SHS). The scores are calculated using a method developed at Meteo Romania (National Meteorological Administration), which has been running operationally since 1996. The meteorological elements evaluated in this verification system are cloud cover, wind speed, fog, glazed frost, hail, frost, minimum and maximum air temperature, as well as the appearance, shape, distribution and intensity of precipitation. The automatic weather forecasting verification system is based on two graphical interfaces, both of them having a specific role in simplifying the user interaction with the database where the information is stored. This work was realized within the World Bank project "Development of a standardized verification mechanism and QMS for the Moldova SHS".
NOx AND O3 VARIABILITY AND ITS RELATION WITH WEATHER CONDITIONS IN IAȘI CITY
Authors: AMIHĂESEI Vlad-Alexandru , SFÎCĂ Lucian , APOSTOL Liviu , LEAHU Alina
Published: November 2020

The paper presents the temporal variability of surface ozone (O3) and its precursors (oxides of nitrogen - NOx) from January 2012 to December 2015. In the same time, this study is aimed to explore the influence of the weather elements on these two major atmospheric pollutants in the area of Iași city. The maximum record of nitrogen oxides reached during the 4 analyzed years was 1200 μ/m-3 on October 27, 2015, a period of the year when atmospheric stability prevails. During the warm season (considered from May to September) the highest concentration of ozone was recorded at 155 μ/m-3. The winds direction from SSE or NNW and the winds speed greater than 2 m/s can significantly increase the concentration of the O3 and NOx respectively. Also, the stable atmospheric conditions can increase especially the concentration of the nitrogen dioxides. The statistical results illustrate a strong Pearson's correlation of surface ozone with solar radiation/maximum air temperature (r >0.5). The correlations were strongest during the summer months. Using the composite method, between warm season and cold season a difference of the pollutants concentration greater than 30 units for NOx was observed. Synoptic conditions associated with high pollution are also described.
PATTERNS OF URBAN FIRE OCCURENCE IN IASI CITY (ROMANIA)
Authors: Bulai Anca – Teodora , Rosu Lucian , Banica Alexandru
Published: November 2020

Fire incidents are a problem of major importance for cities, as they affect the lives of a large population and produce significant material damages. Assessing the temporal and spatial distribution of fires is an important stage in order to efficiently manage this issue. Using a comprehensive database for a five year period, the present study tries to identify certain patterns and specificities by analyzing the occurrence of urban fires, grouped by their main causes and damages, at different time scale and integrating the information from street level to urban district and, finally, at city level.
The spatial distribution of the number of fires follows the center-periphery model, overlapping the neighborhoods with multiple functions (residential, administrative and cultural). The industrial area also concentrates a bigger number of fires, these brownfields being used by homeless population which make use of garbage as fire material. Applying the location quotient was an opportunity to highlight cross-scale the concentration of fires and revealed that the neighborhoods located at the periphery are more vulnerable to fires. The results can be used for further, more comprehensive studies of urban fire risk assessment and can also became the basis for (re)configuring the emergency services, in particular, and urban planning, in general.
THE HAIL FALLS AT THE MOLDAVIA LEVEL AND THE IMPORTANCE OF THE HAIL SUPPRESSION UNIT "MOLDOVA 1" IAȘI
Authors: Axinte Aurel-Dănuț
Published: November 2020

Moldavia, by its location at the contact between temperate-continental climate and that with excessive influences, is characterized by extreme weather events. Such weather's manifestations during of warm period of the year drive at generate of storms, which allow the hail's formation. Based on this study, for the studied area, of importance is the western air mass movements (47.1%), followed by those from northwestern (13.4%). Also, very important are the south air-mass movements (10.8%), all of these in the cyclonic pattern. So, the higher dimensions of the hail (15 to 30 mm in diameter) were recorded on western or northwestern air-mass movements. Also, in these types of air-mass movements can be distinguished the higher speed of the convective clouds, speeds what can reach even 60 to 80 km/h especially at the contact areas between mountains and low lands from surroundings. At the regional level, regarding suppress hail falls, is operative Hail Suppress Unit "Moldova 1" Iasi. This program has proven its efficiency for the protected area of Cotnari (Iasi County), respectively, that of Husi (Vaslui County). Therefore, for Cotnari Protected Area as a result of the hail falls from June 23rd, 2017, the active operations into the atmosphere have proven themselves efficiency. As a result, after a few minutes from the cloud's entrance into the active intervention area, the seeding of the convective cells with the anti-hail rockets' aid, the dimensions of the hail have descended very much in the high reflectivity area of the convective cells. In the future, it's desired to spread this program at the regional and national level and continuing of the researchers in this field to proves the utility of this program and, eventually, enacting other hail suppress technologies, such aviation or ground-based seeding methods. The last process is ideal for rain' augmentation from orographic clouds.
ANALYSIS OF LAND USE CHANGES AND THEIR INFLUENCE ON SOIL FEATURES. CASE STUDY: SECAȘ VILLAGE, TIMIȘ COUNTY (ROMANIA)
Authors: Copăcean Loredana , Zisu Ionut , Mazăre Valentina , Cojocariu Luminiţa
Published: November 2020

The soil, regarded as a natural resource, but also as a determinant element of the living standards of rural communities, manly agricultural, may be influenced, directly and indirectly, by the modality of land organizing and use. Starting from this consideration, through this study, the spatial and temporal evolution of land use is being pursued, particularly that of forest areas and wooded grasslands. The goal is to notice the changes that have occurred over a 30-year period and the manner how these changes are reflected on the soil features. The researches presented in this paper have been taking place in the north-eastern hilly area of Timiş County, that area having entirely a rural character. For realizing this study satellite images, topographical and cadastral maps, from different time periods, national and international databases, data from specialty literature were used. To all these we should add direct observations in the field, topographic surveys and information collected from local authorities. The processing of cartographic materials and data and scientific information has been realized with Geographical Information Systems specific applications. The obtained result has been expressed in the form of thematic maps, in graphic form or as statistical analysis. At the level of the analyzed area, the obvious changes in the land use, registered over time, are caused by a number of factors, such as: the organization form, from communist to capitalist policies, leaving agricultural land as fallow ground, reduction in livestock, changing land use etc. All these changes have caused the extension of the wooded grasslands, reduction of arable land, installing inferior forest vegetation in qualitative and quantitative terms etc. As a result, the soil, one of the most important natural resources, is degraded qualitatively, underexploited, and on the other hand, its role as a direct and indirect food producer for local communities is significantly reduced.
IDENTIFICATION OF DROUGHT EXTENT BASED ON VCI USING SENTINEL DATA: A CASE STUDY OF THE EASTERN OF IAŞI COUNTY
Authors: Macarof Paul , Statescu Florian , Birlica Cristian Iulian , Gherasim Paul
Published: November 2020

In this study was analyzed zones affected by drought using Vegetation Condition Index (VCI), that is based on Normalized Difference Vegetation Index (NDVI). This fact, drought, is one of the most wide -spread and least understood natural phenomena. In this paper was used remote sensing (RS) data, kindly provided by The European Space Agency (ESA), namely Sentinel-2 (S-2) Multispectral Instrument (MSI) and wellkonwn images Landsat 8 Operational Land Imager (OLI). The RS images was processed in SNAP and ArcMap. Study Area, was considered the eastern of Iasi county. The main purpose of paper was to investigating if Sentinel images can be used for VCI analysis.
DISTRIBUTION OF CLOUDINESS ON THE CENTRAL PLATEAU OF MOLDAVIA
Authors: Tiron Mihăiţă
Published: November 2020

The distribution of cloudiness on the Central Plateau of Moldavia is almost similar with that of other hilly areas of Romania, although the mentioned area are located in the east of Romania, where continental influences are present. In the Central Moldovan Plateau. The values of the cloudiness are higher than in the south-eastern areas of Romania, due to specific conditions. In winter the values are raised by the lower temperatures, sometimes generated by the presence of the Euro-Asian Anticyclone and by the high frequency of the thermal inversions. In addition, there is an intensification of the passages of Mediterranean cyclones, often above the anticyclonic cold air. At the end of spring and in the first half of summer, the western circulation intensifies, to the north of the Carpathians, as it enters the studied area. The Central Plateau of Moldavia is a relatively high area, located in the front of the predominant north-western local circulation, a fact that produces slight orographic convection in the case of north component circulations. The annual average of cloudiness is heavily influenced by the genesis of stratiform clouds. The multiannual regime shows decreases of the values. The annual regime is similar for entire Central Plateau of Moldova. In the Central Plateau of Moldavia, both the total and low cloudiness recorded has the highest average in December and the lowest average in August. Total hourly cloudiness recorded two main classes of values between 4-6, with presence in the months of warm semester and 6-8 tenths, characteristic of the cold semester. The low cloudiness presents, in the territory, small differencies for the annual averages and higher differencies than the total cloudiness regime. Diurnal, the low cloudiness exceeds 6 tenths only in the mornings of December, in Vaslui and values below 2 tenths occur only on the nights of June, July, August and September in whole area. The values in the territory are similar, only in the high areas we can see a slight increase in the number of clear sky days, with a corresponding decrease in the number of cloudy and covered days.
THE TECHNOLOGICAL WATER NITROGEN COMPOUNDS DYNAMICS IN THE EXPERIMENTAL PONDS, INLET AND OUTLET CHANNELS
Authors: Petrea Ștefan-Mihai , Mogodan Alina , Metaxa Isabelle , Platon Cătălin , Costache Mioara , Simionov Ira-Adeline
Published: November 2020

This study aims to identify proper solutions that can improve the sustainability of cyprinids pond aquaculture in terms of nitrogen releases to the environment. Therefore, two experimental variants, based on polyculture, respectively integrated multi-trophic aquaculture (IMTA) concept were tested, as follows: PCP – polyculture of common carp (CC) + grass carp (GC) + bighead carp (BC) + silver carp (SC); CP-PP – net divided pond with CC monoculture in CP part and CC+GC+BC+SC polyculture in PP part. In order to determine the nitrogen accumulation at the pond level, samples of water, sediments, fish meat and reed were analyzed. The results indicate that the highest nitrogen compounds concentrations in pond water were registered at CP part of CP-PP pond. However, the nitrogen concentration in pond effluents was significant higher in case of CP-PP pond, compared with PCP pond. The nitrogen compounds concentration of sediments registered the highest values in the ponds outlet area. Also, CP-PP pond recorded higher nitrogen concentration in sediments, compared with PCP pond. The CC registered the highest nitrogen compounds concentration in case of PP pond area, followed by CP pond area and PCP pond. Not significant correlation was found between reed and pond water/ fish meat/ sediments in terms of nitrogen compounds concentration. It can be concluded that the CP-PP pond feeding management, together with the tested technical solution (pond dividing) generated better water conditioning performances.
CONSIDERATION ON THE ATMOSPHERIC PRECIPITATIONS IN THE CENTRAL PLATEAU OF MOLDAVIA
Authors: Mihăiță Tiron
Published: November 2020

Atmospheric precipitation represents one of the important climatic parameters that characterize the individuality of the climate of the regions, by its decisive influence on the climatic characteristics, but also on the geographic landscape. Therefore, this parameter is important from a theoretical point of view, but also a practical importance through the direct impact and the modifications that they bring to the activity of some important fields such as agriculture, transport, construction, tourism etc. In the present paper is intended to contribute to the scientific knowledge of this important climatic element in the Central Moldavian Plateau. The average of thew annual, semestrial and monthly precipitation quantities from the Central Moldovan Plateau were analyzed. The average annual values of the atmospheric precipitation in the Central Moldavian Plateau are slightly lower than in other regions of Romania (except for the Iași Coast), due to the continental influence, which is also manifested by the high percentage of the average precipitation in the warm semester and by summer. June is the month with the highest average amounts of rainfall, and February (isolated January), the month with the smallest average quantities.
Clinical application of polymorphic variants of the genes ESR1 and CYP2D6*4 in patients with breast and endometrial cancer
Authors:   Cherkasy Regional Oncology Dispensary, Ukraine, Paliychuk O.V. , Polishchuk L.Z. ,   R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology NAS of Ukraine, Kyiv, Rossokha Z.I. ,   SI Reference-centre for molecular diagnostic MH of Ukraine, Kyiv
Published: November 2020

The objective: determining gene polymorphism features ERS1, CYP2D6 in patients with breast cancer (RHZ) and endometrial cancer (EC) and the impact assessment studied genetic characteristics compared to receptor status (immunohistochemical determination of expression levels of ER, PR) tumors and the results of the treatment. Patients and methods. article presents the results of complex clinical, morphological, clinical-genealogical, and molecular-genetic examination of 28 females: 19 patients with breast cancer (BC), 9 patients with endometrial cancer (EC), including 5 patients with primary-multiple tumors (PMT) with and without tumor pathology aggregation in families. Results. The It was determined that in patients’ families malignant tumors of breast, uterine body and/or ovaries prevail that corresponds to Lynch type II syndrome (family cancer syndrome). Molecular-genetic examination of genomic DNA of peripheral blood and histological sections for the presence of SNPs of ESR and CYP2D6*4 genes comparing with the results of immunohistochemical study of tumors for receptors ER and PR status have not found associations between these characteristics; although among EC patients the occurrence of genotypes 397ТТ and 351АА was significantly higher comparing with BC patients (55.55% and 10.5% for genotype 397ТТ,and 15.8% for genotype 351АА, respectively). At the same time the patients with BC and primary-multiple tumors (PMT) of female reproductive system organs (FRSO) that carried mutations in BRCA1 in all the cases demonstrated positive ER and PR receptor status and adverse combinations of polymorphous variants of the genes ESR1 (397СС, 397ТС) and CYP2D6*4 (1846G, 1846GA), suggesting combined effect of these factors on the development of malignant neoplasias of FRSO in families with positive family cancer history. In BC patients, receiving standard hormone therapy with tamoxifen, those, who had genotype 1846GG of the gene CYP2D6*4, in 3 patients (15.8%) of 19 (100%) patients disease recurrence was diagnosed. Conclusion. The obtained results allow clinical use of the assessment of polymorphism frequency of the genes ESR1 and CYP2D6*4 for selection of individual hormone therapy regimens schemes for BC patients, to increase efficacy of dispensary observation after finishing of special therapy for such patients, and also personalization of complex and combined treatment regimens. Key words: breast cancer, endometrial cancer, family cancer syndrome, single nucleotide polymorphisms (SNPs) of the genes ESR1, CYP2D6*4.
The cytologic conclusion in accordance a terminology system The Bethesda system 2014: what’s new?
Authors:   Medical laboratory Synevo, Rykovа O.V. , Bogomaz T.P. ,   Medical laboratory Synevo
Published: November 2020

The paper presents the principles of the conclusions Pap test in accordance with the terminology system Bethesda, 2014, and their correlation with other classifications cytological findings. Key words: cervical cancer, cervical screening, traditional cytology, liquid-based cytology, PAP-test, The Bethesda system.