bluuebunny/crossref_metadata_2025 huggingface dataset:
A Psychometric Analysis of the Student Version of the Perceptions of	Inclusion Questionnaire (PIQ)
Authors: Zurbriggen Carmen L. A. , Venetz Martin , Schwab Susanne , Hessels Marco G. P.
Published: December 2017

Abstract. The German version of the Perception of Inclusion Questionnaire (PIQ), which is used to assess students’ emotional inclusion, social inclusion, and academic self-concept, was analyzed with the multi-unidimensional graded response model (GRM) and investigated for differential item functioning (DIF) between students with and without learning difficulties (LD). The PIQ was administered to 823 primary school students in Switzerland ( Mage = 11.94, SD = 1.01 years), of which 190 were classified as having LD. Results show that the PIQ is a reliable instrument for assessing students’ perceptions of their inclusion at school, especially in the lower ranges of the scales. No bias was detected for any items of the PIQ’s three scales in relation to the exogenous variable LD, with the exception of one item that showed a minor deviation.
Emotional Perception and Distortion Correlates With Rorschach Cognitive and Interpersonal Variables
Authors: Miguel Fabiano Koich , Amaro Marcia Caroline Portela , Huss Eduardo Yudi , Zuanazzi Ana Carolina
Published: December 2017

Abstract. Although emotional intelligence is frequently measured with performance tasks, they are often correlated with self-report measures of personality. The present research compared the scores of two performance tests: the Rorschach Inkblot Method for personality (scored using R-PAS), and the Computerized Test of Primary Emotions Perception for emotional perception and understanding, branches of emotional intelligence. Participants were 93 Brazilian people, including undergraduates and psychiatric outpatients. Significant correlations were found, ranging from .20 to .37. The results indicate that the ability to perceive emotional expressions in people’s faces is related to empathy and interest in human interaction, attention to details, integrative thinking, and complex cognitive processing. Distortion in emotional perception, that is perceiving emotions that were not present, correlated with thought and perception disturbances.
Longitudinal Associations Among Psychological Issues and Problematic	Use of Smartphones
Authors: Kim Jung-Hyun
Published: December 2017

Abstract. One of the critical limitations of previous research on the association between problematic use of media and psychological factors is that the proposed causality between them is mostly based on cross-sectional data. Responding to this limitation, the present study investigated longitudinal causality associations among loneliness, problematic use of smartphones, face-to-face interaction, smartphone-mediated communication, and need for social assurance with cross-lagged panel models. The results suggest that loneliness leads to problematic use of smartphones, which reduces face-to-face interaction while increasing need for social assurance. However, need for social assurance fueled by excessive smartphone use is usually not gratified, and eventually leads to greater loneliness.
Weight of Water Dropped by Hurricane Harvey Flexed Earth’s Crust
Authors: Montanari Shaena
Published: December 2017

The precipitation that fell during the storm depressed the ground in parts of Texas, Louisiana, Arkansas, and Mississippi by as much as 1.8 centimeters in some places.
Threatened Sea Turtles in Hawaii Losing Ground to Rising Oceans
Authors: Fox Alex
Published: December 2017

By midcentury, the Hawaiian green sea turtle could lose nesting beaches of increasing importance on Oahu, the most populous island in the chain.
Unforeseen swimming and gliding mode of an insect gut symbiont, Burkholderia sp. RPE64, with wrapping of the flagella around its cell body
Authors: Kinosita Yoshiaki , Kikuchi Yoshitomo , Mikami Nagisa , Nakane Daisuke , Nishizaka Takayuki
Published: December 2017

A bean bug symbiont, Burkholderia sp. RPE64, selectively colonizes the gut crypts by flagella-mediated motility: however, the mechanism for this colonization remains unclear. Here, to obtain clues to this mechanism, we characterized the swimming motility of the Burkholderia symbiont under an advanced optical microscope. High-speed imaging of cells enabled the detection of turn events with up to 5-ms temporal resolution, indicating that cells showed reversal motions (θ ~ 180°) with rapid changes in speed by a factor of 3.6. Remarkably, staining of the flagellar filaments with a fluorescent dye Cy3 revealed that the flagellar filaments wrap around the cell body with a motion like that of a ribbon streamer in rhythmic gymnastics. A motility assay with total internal reflection fluorescence microscopy revealed that the left-handed flagellum wound around the cell body and propelled it forward by its clockwise rotation. We also detected periodic-fluorescent signals of flagella on the glass surface, suggesting that flagella possibly contacted the solid surface directly and produced a gliding-like motion driven by flagellar rotation. Finally, the wrapping motion was also observed in a symbiotic bacterium of the bobtail squid, Aliivibrio fischeri, suggesting that this motility mode may contribute to migration on the mucus-filled narrow passage connecting to the symbiotic organ.
Schizophrenia-risk and urban birth are associated with proteomic changes in neonatal dried blood spots
Authors: Cooper Jason D. , Ozcan Sureyya , Gardner Renee M. , Rustogi Nitin , Wicks Susanne , van Rees Geertje F. , Leweke F. Markus , Dalman Christina , Karlsson Håkan , Bahn Sabine
Published: December 2017

In the present study, we tested whether there were proteomic differences in blood between schizophrenia patients after the initial onset of the disorder and controls; and whether those differences were also present at birth among neonates who later developed schizophrenia compared to those without a psychiatric admission. We used multiple reaction monitoring mass spectrometry to quantify 77 proteins (147 peptides) in serum samples from 60 first-onset drug-naive schizophrenia patients and 77 controls, and 96 proteins (152 peptides) in 892 newborn blood-spot (NBS) samples collected between 1975 and 1985. Both serum and NBS studies showed significant alterations in protein levels. Serum results revealed that Haptoglobin and Plasma protease C1 inhibitor were significantly upregulated in first-onset schizophrenia patients (correctedP < 0.05). Alpha-2-antiplasmin, Complement C4-A and Antithrombin-III were increased in first-onset schizophrenia patients (uncorrectedP-values 0.041, 0.036 and 0.013, respectively) and also increased in newborn babies who later develop schizophrenia (P-values 0.0058, 0.013 and 0.044, respectively). We also tested whether protein abundance at birth was associated with exposure to an urban environment during pregnancy and found highly significant proteomic differences at birth between urban and rural environments. The prediction model for urbanicity had excellent predictive performance in both discovery (area under the receiver operating characteristic curve (AUC) = 0.90) and validation (AUC = 0.89) sample sets. We hope that future biomarker studies based on stored NBS samples will identify prognostic disease indicators and targets for preventive measures for neurodevelopmental conditions, particularly those with onset during early childhood, such as autism spectrum disorder.
Schizophrenia and depression, two poles of endocannabinoid system deregulation
Authors: Rodríguez-Muñoz María , Sánchez-Blázquez Pilar , Callado Luis F. , Meana J. Javier , Garzón-Niño Javier
Published: December 2017

The activity of certain G protein-coupled receptors (GPCRs) and of glutamate N-Methyl-D-aspartate receptors (NMDARs) is altered in both schizophrenia and depression. Using postmortem prefrontal cortex samples from subjects with schizophrenia or depression, we observed a series of opposite changes in the expression of signaling proteins that have been implicated in the cross-talk between GPCRs and NMDARs. Thus, the levels of HINT1 proteins and NMDAR NR1 subunits carrying the C1 cytosolic segment were increased in depressives and decreased in schizophrenics, respect to matched controls. The differences in NR1 C1 subunits were compensated for via altered expression of NR1 subunits lacking the C1 segment; thus, the total number of NR1 subunits was comparable among the three groups. GPCRs influence the function of NR1 C1-containing NMDARs via PKC/Src, and thus, the association of mu-opioid and dopamine 2 receptors with NR1 C1 subunits was augmented in depressives and decreased in schizophrenics. However, the association of cannabinoid 1 receptors (CB1Rs) with NR1 C1 remained nearly constant. Endocannabinoids, via CB1Rs, control the presence of NR1 C1 subunits in the neural membrane. Thus, an altered endocannabinoid system may contribute to the pathophysiology of schizophrenia and depression by modifying the HINT1-NR1 C1/GPCR ratio, thereby altering GPCR-NMDAR cross-regulation.
Catalytic asymmetric synthesis of a nitrogen heterocycle through stereocontrolled direct photoreaction from electronically excited state
Authors: Huang Xiaoqiang , Li Xinyao , Xie Xiulan , Harms Klaus , Riedel Radostan , Meggers Eric
Published: December 2017

The reactivity of photoexcited molecules has been extensively studied for decades but until today direct bond-forming reactions of such excited states in a catalytic and asymmetric fashion are restricted to the synthesis of cyclobutanes via [2 + 2] photocycloadditions. Herein, we demonstrate a previously elusive visible-light-induced catalytic asymmetric [2 + 3] photocycloaddition of alkenes with vinyl azides. A wide range of complex 1-pyrrolines are obtained as single diastereoisomers and with up to >99% enantiomeric excess using a simple reaction setup and mild reaction conditions. The reaction is proposed to proceed through the photoexcitation of a complex out of chiral rhodium catalyst coordinated to α,β-unsaturated N-acylpyrazole substrates. All reactive intermediates remain bound to the catalysts thereby providing a robust catalytic scheme (no exclusion of air necessary) with excellent stereocontrol. This work expands the scope of stereocontrolled bond-forming reactions of photoexcited intermediates by providing catalytic asymmetric access to a key nitrogen heterocycle in organic chemistry.
Circadian clock regulates hepatic polyploidy by modulating Mkp1-Erk1/2 signaling pathway
Authors: Chao Hsu-Wen , Doi Masao , Fustin Jean-Michel , Chen Huatao , Murase Kimihiko , Maeda Yuki , Hayashi Hida , Tanaka Rina , Sugawa Maho , Mizukuchi Naoki , Yamaguchi Yoshiaki , Yasunaga Jun-ichirou , Matsuoka Masao , Sakai Mashito , Matsumoto Michihiro , Hamada Shinshichi , Okamura Hitoshi
Published: December 2017

Liver metabolism undergoes robust circadian oscillations in gene expression and enzymatic activity essential for liver homeostasis, but whether the circadian clock controls homeostatic self-renewal of hepatocytes is unknown. Here we show that hepatocyte polyploidization is markedly accelerated around the central vein, the site of permanent cell self-renewal, in mice deficient in circadian Period genes. In these mice, a massive accumulation of hyperpolyploid mononuclear and binuclear hepatocytes occurs due to impaired mitogen-activated protein kinase phosphatase 1 (Mkp1)-mediated circadian modulation of the extracellular signal-regulated kinase (Erk1/2) activity. Time-lapse imaging of hepatocytes suggests that the reduced activity of Erk1/2 in the midbody during cytokinesis results in abscission failure, leading to polyploidization. Manipulation of Mkp1 phosphatase activity is sufficient to change the ploidy level of hepatocytes. These data provide clear evidence that the Period genes not only orchestrate dynamic changes in metabolic activity, but also regulate homeostatic self-renewal of hepatocytes through Mkp1-Erk1/2 signaling pathway.
A conserved ankyrin repeat-containing protein regulates conoid stability, motility and cell invasion in Toxoplasma gondii
Authors: Long Shaojun , Anthony Bryan , Drewry Lisa L. , Sibley L. David
Published: December 2017

Apicomplexan parasites are typified by an apical complex that contains a unique microtubule-organizing center (MTOC) that organizes the cytoskeleton. In apicomplexan parasites such as Toxoplasma gondii, the apical complex includes a spiral cap of tubulin-rich fibers called the conoid. Although described ultrastructurally, the composition and functions of the conoid are largely unknown. Here, we localize 11 previously undescribed apical proteins in T. gondii and identify an essential component named conoid protein hub 1 (CPH1), which is conserved in apicomplexan parasites. CPH1 contains ankyrin repeats that are required for structural integrity of the conoid, parasite motility, and host cell invasion. Proximity labeling and protein interaction network analysis reveal that CPH1 functions as a hub linking key motor and structural proteins that contain intrinsically disordered regions and coiled coil domains. Our findings highlight the importance of essential protein hubs in controlling biological networks of MTOCs in early-branching protozoan parasites.
Leukocyte-Associated Immunoglobulin-like Receptor-1 is regulated in human myocardial infarction but its absence does not affect infarct size in mice
Authors: Ellenbroek Guilielmus H. J. M. , de Haan Judith J. , van Klarenbosch Bas R. , Brans Maike A. D. , van de Weg Sander M. , Smeets Mirjam B. , de Jong Sanne , Arslan Fatih , Timmers Leo , Goumans Marie-José T. H. , Hoefer Imo E. , Doevendans Pieter A. , Pasterkamp Gerard , Meyaard Linde , de Jager Saskia C. A.
Published: December 2017

Heart failure after myocardial infarction (MI) depends on infarct size and adverse left ventricular (LV) remodelling, both influenced by the inflammatory response. Leukocyte-associated immunoglobulin-like receptor 1 (LAIR-1) is an inhibitory receptor of ITAM-dependent cell activation, present on almost all immune cells. We investigated regulation of LAIR-1 leukocyte expression after MI in patients and hypothesized that its absence in a mouse model of MI would increase infarct size and adverse remodelling. In patients, LAIR-1 expression was increased 3 days compared to 6 weeks after MI on circulating monocytes (24.8 ± 5.3 vs. 21.2 ± 5.1 MFI, p = 0.008) and neutrophils (12.9 ± 4.7 vs. 10.6 ± 3.1 MFI, p = 0.046). In WT and LAIR-1−/− mice, infarct size after ischemia-reperfusion injury was comparable (37.0 ± 14.5 in WT vs. 39.4 ± 12.2% of the area at risk in LAIR-1−/−, p = 0.63). Remodelling after permanent left coronary artery ligation did not differ between WT and LAIR-1−/− mice (end-diastolic volume 133.3 ± 19.3 vs. 132.1 ± 27.9 μL, p = 0.91 and end-systolic volume 112.1 ± 22.2 vs. 106.9 ± 33.5 μL, p = 0.68). Similarly, no differences were observed in inflammatory cell influx or fibrosis. In conclusion, LAIR-1 expression on monocytes and neutrophils is increased in the acute phase after MI in patients, but the absence of LAIR-1 in mice does not influence infarct size, inflammation, fibrosis or adverse cardiac remodelling.
An updated reconstruction of basaltic crust emplacement in Tyrrhenian sea, Italy
Authors: Savelli Carlo , Ligi Marco
Published: December 2017

Basaltic crust is present in the oceans and marginal seas. Oceanic accretion from inception to ending may be usefully recognized in small basin setting like the Tyrrhenian. Alternating episodes of strong and moderate extensional tectonics characterized the small Tyrrhenian opening. Hyperextension (drifting) of late-Miocene and latemost Pliocene age was followed by Pliocene and Late Quaternary moderate extension (rifting). Early hyperextension (~7.5–6.3 Ma) acted in the submerged margin of Hercynian Sardinia. Sardinia offshore, E-directed low-angle faults were accompanied by MORB-like volcanism of non linear shape in the shallow Vavilov plain - inherited segment of alpine-age orogen. Late hyperextension (~1.9–1.7 Ma) acted along the central N-S lineament of Vavilov plain, former metamorphic core complex. At the lineament northern side, E-dipping detachment faulting exposed serpentinized peridotite. At the other side, Vavilov volcano was faulted and its east flank tilted westwards. At the same time, volcanism with affinity to transitional MORB induced opening of Marsili basin. The drift episodes were characterized by absence or scarcity of volcanic activity on the conjugated emerged margins. The rift episodes (respectively ~5–1.9 Ma, and ~1/0.8 Ma-Recent) saw growth of major north-south trending volcanoes in bathyal area as intense volcanic activity developed on the continental margins.
Functional characterization and discovery of modulators of SbMATE, the agronomically important aluminium tolerance transporter from Sorghum bicolor
Authors: Doshi Rupak , McGrath Aaron P. , Piñeros Miguel , Szewczyk Paul , Garza Denisse M. , Kochian Leon V. , Chang Geoffrey
Published: December 2017

About 50% of the world’s arable land is strongly acidic (pH ≤ 5). The low pH solubilizes root-toxic ionic aluminium (Al3+) species from clay minerals, driving the evolution of counteractive adaptations in cultivated crops. The food crop Sorghum bicolor upregulates the membrane-embedded transporter protein SbMATE in its roots. SbMATE mediates efflux of the anionic form of the organic acid, citrate, into the soil rhizosphere, chelating Al3+ ions and thereby imparting Al-resistance based on excluding Al+3 from the growing root tip. Here, we use electrophysiological, radiolabeled, and fluorescence-based transport assays in two heterologous expression systems to establish a broad substrate recognition profile of SbMATE, showing the proton and/or sodium-driven transport of 14C-citrate anion, as well as the organic monovalent cation, ethidium, but not its divalent analog, propidium. We further complement our transport assays by measuring substrate binding to detergent-purified SbMATE protein. Finally, we use the purified membrane protein as an antigen to discover native conformation-binding and transport function-altering nanobodies using an animal-free, mRNA/cDNA display technology. Our results demonstrate the utility of using Pichia pastoris as an efficient eukaryotic host to express large quantities of functional plant transporter proteins. The nanobody discovery approach is applicable to other non-immunogenic plant proteins.
High-Temperature Requirement A1 (Htra1) - A Novel Regulator of Canonical Wnt Signaling
Authors: Globus Oriane , Evron Tamar , Caspi Michal , Siman-Tov Ronen , Rosin-Arbesfeld Rina
Published: December 2017

Different cancer types as well as many other diseases are caused by aberrant activation of the canonical Wnt signal transduction pathway, and it is especially implicated in the development and progression of colorectal cancer (CRC). The main effector protein of the canonical Wnt signaling cascade is β-catenin, which binds to the T- cell factor/lymphoid enhancer factor (TCF/LEF) and triggers the activation of Wnt target genes. Here, we identify the serine protease High-Temperature Requirement A1 (HTRA1) as a novel component of the canonical Wnt pathway. We show that the HTRA1 protein inhibits the Wnt/β-catenin signaling, in both paracrine and autocrine manners, and affects the expression of several Wnt target genes. Moreover, HTRA1 forms a complex with β-catenin and reduces the proliferation rates of cells. Taken together, our findings indicate that HTRA1 functions as a novel suppressor of the canonical Wnt signaling pathway.
Identification and expression of CAMTA genes in Populus trichocarpa under biotic and abiotic stress
Authors: Wei Ming , Xu Xuemei , Li Chenghao
Published: December 2017

The calmodulin-binding transcription activators (CAMTAs) transcription factor family plays an important role in normal plant growth and development, as well as in biotic and abiotic stress resistance. In this study, we identified seven CAMTA genes across the whole genome of Populus trichocarpa and analyzed the expression patterns of PtCAMTAs in the root and leaf tissues. Promoter cis-element analysis indicated that most CAMTA genes contained stress- or phytohormone-related cis-elements. Quantitative real-time reverse transcription-PCR (qRT-PCR) indicated indicated that PtCAMTAs were induced by mannitol, NaCl, cold stress, pathogenic infection with A. alternata, and phytohormone treatments with abscisic acid, salicylic acid, and methyl jasmonate. We analyzed the expression of homologous genes between P. trichocarpa and P. ussuriensis and alternative splicing forms of PtCAMTA genes under cold stress. We also performed a network interaction analysis for PtCAMTA proteins to predict their interactions and associations. The results of the present study serve as a basis for future functional studies on the Populus CAMTA family.
Thermoluminescence of coral skeletons: a high-sensitivity proxy of diagenetic alteration of aragonite
Authors: Takada Noriyuki , Suzuki Atsushi , Ishii Hiroshi , Hironaka Katsuyuki , Hironiwa Takayuki
Published: December 2017

Diagenetic alteration of aragonite coral skeletons causes changes in their chemical and isotopic compositions. Such altered coral samples are unsuitable for age dating or paleoclimate reconstructions. Recently developed microanalysis techniques have elucidated secondary aragonite precipitation and calcite overgrowth on primary aragonitic coral skeletons, but an effective screening method for bulk samples is still desirable. Although powder X-ray diffraction (XRD) analysis is widely used for this purpose, its detection limit for calcite (1–2% at best) is not sufficient to detect very small amounts of diagenetic calcite. Here, we propose that thermoluminescence (TL) spectra can be used to detect the presence of tiny amounts of secondary calcite in coral skeletons. We used a TL spectrometer with a Fourier-transform detector to detect the calcite component in TL spectra of powdered skeletons of modern and fossil corals (from 127 ka and 3.5 Ma) in which calcite was not detectable by XRD. The key element is manganese, because the TL emission efficiency and the partition coefficient of Mn are greater for calcite than for aragonite. As a result, the calcite spectral component becomes evident. Thus, the TL spectroscopic technique is a highly sensitive tool for screening fossil corals for diagenetic alteration.
New Types of Experiments Reveal that a Neuron Functions as Multiple Independent Threshold Units
Authors: Sardi Shira , Vardi Roni , Sheinin Anton , Goldental Amir , Kanter Ido
Published: December 2017

Neurons are the computational elements that compose the brain and their fundamental principles of activity are known for decades. According to the long-lasting computational scheme, each neuron sums the incoming electrical signals via its dendrites and when the membrane potential reaches a certain threshold the neuron typically generates a spike to its axon. Here we present three types of experiments, using neuronal cultures, indicating that each neuron functions as a collection of independent threshold units. The neuron is anisotropically activated following the origin of the arriving signals to the membrane, via its dendritic trees. The first type of experiments demonstrates that a single neuron’s spike waveform typically varies as a function of the stimulation location. The second type reveals that spatial summation is absent for extracellular stimulations from different directions. The third type indicates that spatial summation and subtraction are not achieved when combining intra- and extra- cellular stimulations, as well as for nonlocal time interference, where the precise timings of the stimulations are irrelevant. Results call to re-examine neuronal functionalities beyond the traditional framework, and the advanced computational capabilities and dynamical properties of such complex systems.
Identification of a CARM1 Inhibitor with Potent In Vitro and In Vivo Activity in Preclinical Models of Multiple Myeloma
Authors: Drew Allison E. , Moradei Oscar , Jacques Suzanne L. , Rioux Nathalie , Boriack-Sjodin Ann P. , Allain Christina , Scott Margaret Porter , Jin Lei , Raimondi Alejandra , Handler Jessica L. , Ott Heidi M. , Kruger Ryan G. , McCabe Michael T. , Sneeringer Christopher , Riera Thomas , Shapiro Gideon , Waters Nigel J. , Mitchell Lorna H. , Duncan Kenneth W. , Moyer Mikel P. , Copeland Robert A. , Smith Jesse , Chesworth Richard , Ribich Scott A.
Published: December 2017

CARM1 is an arginine methyltransferase with diverse histone and non-histone substrates implicated in the regulation of cellular processes including transcriptional co-activation and RNA processing. CARM1 overexpression has been reported in multiple cancer types and has been shown to modulate oncogenic pathways in in vitro studies. Detailed understanding of the mechanism of action of CARM1 in oncogenesis has been limited by a lack of selective tool compounds, particularly for in vivo studies. We describe the identification and characterization of, to our knowledge, the first potent and selective inhibitor of CARM1 that exhibits anti-proliferative effects both in vitro and in vivo and, to our knowledge, the first demonstration of a role for CARM1 in multiple myeloma (MM). EZM2302 (GSK3359088) is an inhibitor of CARM1 enzymatic activity in biochemical assays (IC50 = 6 nM) with broad selectivity against other histone methyltransferases. Treatment of MM cell lines with EZM2302 leads to inhibition of PABP1 and SMB methylation and cell stasis with IC50 values in the nanomolar range. Oral dosing of EZM2302 demonstrates dose-dependent in vivo CARM1 inhibition and anti-tumor activity in an MM xenograft model. EZM2302 is a validated chemical probe suitable for further understanding the biological role CARM1 plays in cancer and other diseases.
New tests, new tools: mobile and connected technologies in advancing psychiatric diagnosis
Authors: Roberts Laura Weiss , Chan Steven , Torous John
Published: December 2017

Mental health is an area of growing interest in the digital health space. Mobile and connected technologies offer new tools that can potentially aid in both the diagnostic and interventional aspects of psychiatric care. To understand the potential of these digital tools in psychiatry, this paper offers an overview of the development, current research, clinical use cases, and next steps necessary to realize the potential of digital health in mental health. Focusing on smartphones’ and wearable sensors’ ability to advance clinical data collection via multiple domains: self-report, behavioral, and physiological, we explore opportunities and challenges in translating these technologies into clinical care tools that can advance how we understand and approach mental illness.
Copper(i) complexes based on ligand systems with two different binding sites: synthesis, structures and reaction with O2
Authors: Li S. T. , Braun-Cula B. , Hoof S. , Limberg C.
Published: December 2017

Ligands with two different binding sites were synthesized and their dicopper(i) complexes were shown to activate O2in 1 : 1 reactions to provide reactive bis(μ-oxido) intermediates.
Reaction of tin(iv) phthalocyanine dichloride with decamethylmetallocenes (M = CrII and CoII). Strong magnetic coupling of spins in (Cp*2Co+){SnIVCl2(Pc˙3−)}˙−·2C6H4Cl2
Authors: Konarev Dmitri V. , Troyanov Sergey I. , Shestakov Alexander F. , Yudanova Evgeniya I. , Otsuka Akihiro , Yamochi Hideki , Kitagawa Hiroshi , Lyubovskaya Rimma N.
Published: December 2017

Decamethylmetallocenes form complexes (Cp*2Co+){SnIVCl2(Pc˙3−)}˙−·2C6H4Cl2 (1) and {(Cp*CrCl2)(SnIVCl(Pc2−))}·C6H4Cl2 (2) whose structures and properties are discussed.
Facile synthesis and color-tunable properties of monodisperse β-NaYF4:Ln3+ (Ln = Eu, Tb, Tm, Sm, Ho) microtubes
Authors: Yang Junfeng , Song Lina , Wang Xiaoxue , Dong Jianchao , Gan Shucai , Zou Lianchun
Published: December 2017

In this study, monodisperse and uniform β-NaYF4 hexagonal microtubes were successfully synthesized via a simple hydrothermal method without any organic surfactants, employing Y(OH)CO3 colloid spheres as precursors.
Accelerated atomic-scale exploration of phase evolution in compositionally complex materials
Authors: Li Y. J. , Savan A. , Kostka A. , Stein H. S. , Ludwig A.
Published: December 2017

Combining nanoscale-tip arrays with combinatorial thin film deposition and processing as well as direct atomic-scale characterization (APT and TEM) enables accelerated exploration of the temperature- and environment-dependent phase evolution in multinary materials systems.
Towards magnetic responsive chalcogenides for efficient separation in water treatment: facile synthesis of magnetically layered chalcogenide Fe3O4/KMS-1 composite adsorbents and their zinc removal application in water
Authors: Li Jian-Rong , Xu Lei , Fu Ming-Lai , Wang Yun-Xia , Xiao Hang
Published: December 2017

A novel easily separated magnetic chalcogenide based composite, Fe3O4/KMS-1, was successfully synthesized under vigorous stirring of a mixture in ethanol solution.
Highly sensitive, durable and stretchable plastic strain sensors using sandwich structures of PEDOT:PSS and an elastomer
Authors: Fan Xi , Wang Naixiang , Wang Jinzhao , Xu Bingang , Yan Feng
Published: December 2017

A stretchable plastic strain sensor was fabricated, showing high sensitivity and a broad strain-sensing region with good durability.
Freezing temperature controlled deep eutectic solvent dispersive liquid–liquid microextraction based on solidification of floating organic droplets for rapid determination of benzoylureas residual in water samples with assistance of metallic salt
Authors: Yang Miyi , Hong Kun , Li Xiaoqiang , Ge Fangji , Tang Yuqing
Published: December 2017

A hydrophobic deep eutectic solvent worked as an extractant to extract benzoylureas with assistance of FeCl3 contained dispersive-demulsified solvent.
Synthesis of pH-responsive nanocomposites of gold nanoparticles and graphene oxide and their applications in SERS and catalysis
Authors: Yao Aihua , Fu Qingge , Xu Ling , Xu Yan , Jiang Wenqi , Wang Deping
Published: December 2017

Au NPs–GO nanocomposites, synthesized by decorating Au NPs onto P4VP-grafted GO sheets, displayed pH-dependent catalytic activity towards the reduction of 4-nitrophenol, and selective SERS detection of negatively-charged dye molecules.
Rapid and facile synthesis of hierarchically mesoporous TiO2–B with enhanced reversible capacity and rate capability
Authors: Liu Yubin , Guo Minghuang , Liu Zhenwei , Wei Qiaohua , Wei Mingdeng
Published: December 2017

A rapid and facile synthetic route has been developed to fabricate hierarchically mesoporous TiO2–B, which is composed of nanoparticles and exhibits enhanced reversible capacity and rate capability in lithium ion batteries.
Sensing mechanism of ethanol and acetone at room temperature by SnO2 nano-columns synthesized by aerosol routes: theoretical calculations compared to experimental results
Authors: Abokifa Ahmed A. , Haddad Kelsey , Fortner John , Lo Cynthia S. , Biswas Pratim
Published: December 2017

A useful feedback loop: insights from theoretical calculations are used for rational design of nanosensors and for elucidating surface interactions.
Preparing Future SLPs for the Clinical World of Cultural-Linguistic Diversity
Authors: Quach Wendy , Tsai Pei-Tzu
Published: December 2017

Language use in the United States has become increasingly diverse. One in five U.S. residents speaks a language other than English at home, with over 350 languages spoken in the nation. There is a clear need for speech-language pathologists (SLPs) who are culturally and linguistically competent to serve this diverse population. We designed a specialized graduate training program, Project Tapestry, funded by the U.S. Department of Education, to meet this need in our community. The project includes workshops on cultures, languages, and counseling for graduate students to work with clients and families with diverse backgrounds. Students also learn about collaborating with interpreters and translators. Project Tapestry prepares future SLPs with the knowledge to diagnose linguistic differences and disorders, sensitivity and awareness to identify cultural differences, and skills to communicate and implement clinical plans that consider cultural-linguistic differences. We will discuss preliminary outcomes of the project.
SEFDM over satellite systems with advanced interference cancellation
Authors: Ghannam Hedaia , Darwazeh Izzat
Published: December 2017

For high data rates satellite systems, where multiple carriers are frequency division multiplexed with a slight overlap, the overall spectral efficiency is limited. This work applies highly overlapped carriers for satellite broadcast and broadband scenarios to achieve higher spectral efficiency. Spectrally efficient frequency division multiplexing (SEFDM) compresses subcarrier spacing to increase the spectral efficiency at the expense of orthogonality violation. SEFDM systems performance degrades compared to orthogonal signals, unless efficient interference cancellation is used. Turbo equalisation with interference cancellation is implemented to improve receiver performance for variable coding, compression and modulation/constellation proposals that may be applied in satellite communications settings. Such parameters may be set to satisfy pre‐defined spectral efficiency values for a given quality index or associated application. Assuming low‐density parity check coded data, the work proposes two approaches to receiver design: a simple matched filter approach and an approach utilising an iterative interference cancellation structure specially designed for SEFDM. Mathematical models and simulations studies are presented indicating promising gains to be achieved for SEFDM transmission with advanced transceiver architectures at the cost of increased complexity at the receiver.
Minimum steady corona inception voltage calculation method under rain condition
Authors: Hu Qin , He Gaohui , Shu Lichun , Jiang Xingliang , Liu Yanqing , Li Yongfu , Peng Huadong , Wu Weiwei
Published: December 2017

As the most common precipitation form, rain‐lead corona problems are inevitably faced by designers of transmission lines. Through long‐term observations of corona inception process under rain conditions by ultraviolet camera, a definition of minimum steady corona inception voltage is presented, which is more useful for practical application. To predict the minimum steady corona inception voltage, water droplet deformation model of smooth conductor is promoted based on the principle of minimising energy in this publication, which takes the influence of electric field force into consideration. Critical breakdown voltage and corresponding critical geometric dimensions of specific water droplet are calculated through the deformation model. The accuracy of the presented deformation model is proved to be >95%, by verification tests performed in a corona cage. Corona discharge model presented in the previous work is adopted to predict the water droplet corona inception voltage of given geometric dimensions. Finally, through the calculation results of both models, the defined minimum steady corona inception voltage of smooth conductor is calculated when there exist rain droplets on conductor lower surface. Also, the calculation error of minimum steady corona inception voltage is ∼8.0% when compared with the validation experiments.
Minimum switching losses for solving distribution NR problem with distributed generation
Authors: Badran Ola , Mokhlis Hazlie , Mekhilef Saad , Dahalan Wardiah , Jallad Jafar
Published: December 2017

Power losses in a distribution system are commonly minimised via optimal network reconfiguration (NR). Previously, research on NR was focused on planning, where the final configuration reporting the lowest power losses being the main goal. However, power losses during switching operations from the original state to the optimal state of configuration were not considered. This study discusses the optimal switching path for minimising power losses when reconfiguring a network. The simultaneous optimal NR and distributed generation (DG) output was also proposed. The proposed methodology involves: (i) optimal NR and DG output simultaneously and (ii) optimal switching path to convert the network from the initial configuration to the final configuration obtained from (i). The selected optimisation technique in this study is the firefly algorithm. The proposed method was tested using IEEE 33‐bus, 69‐bus, and 118‐bus radial distribution networks, while also accounting for static and dynamic loads. The results confirmed the effectiveness of the proposed method in determining the optimal path of switching operations, as well as the optimal network configuration and optimal output of DG units.
Low‐frequency harmonic resonance analysis and suppression method of modular multilevel converter
Authors: Yue Yufei , Xu Qianming , Shuai Zhikang , He Zhixing , Guo Peng , Li Yan , Luo An , Shen John
Published: December 2017

Modular multilevel converters (MMCs) become increasingly attractive in high‐voltage dc (HVDC) transmission systems. However, the internal poorly damped characteristic can easily lead to low‐frequency harmonic resonance, affecting the stability of MMC. In this study, the equivalent model of MMC is established to reveal the low‐frequency harmonic resonance, including intrinsic harmonic resonance and potential harmonic resonance. To suppress the harmonic resonance, a circulating current suppressing method based on active damping is proposed to improve the internal damped characteristic. In order to enhance the control effectiveness, the circulating current reference is modified through a dual feedback closed‐loop control involving arm voltages and currents as well as the power feedforward loop in the proposed suppression strategy. Proper parameters are designed to apply the reasonable damping characteristic of MMC. Finally, the proposed method is implemented and verified with an MMC‐HVDC system in the RT‐LAB simulator platform.
Miniaturised ISM band HMSIW band‐pass filter loaded with wide U slot
Authors: Sandhya Ramalingam , Habiba Hyder Ali Umma
Published: December 2017

In this study, two half‐mode substrate integrated waveguide (HMSIW) filters are proposed by introducing wide U slot in the conventional SIW (substrate integrated waveguide) structure. In the first case, lower ISM (industrial, scientific and medical radio) band HMSIW filter is designed by extending the centre stub, thereby controlling the resonant frequency and bandwidth. In the second case, higher ISM band HMSIW filter is designed by shorting the extended stub using via. These filters are having a compact core size of 26 mm × 11 mm and work at 2.4 and, 5.8 GHz with a fractional bandwidth of 4.0 and 2.6%, respectively. The filter is fabricated with a single layer standard printed circuit board process. The measured results are good and in agreement with simulated results. The band‐pass filter structure has the advantage of low insertion loss, good return loss, sharp side band rejection and compact size.
Nitrogen‐doped hollow carbon spheres as a support for the synthesis of multifunctional composites
Authors: Yang Jiayi , Miao Teng , Zhang Zhuo , Qian Zhenhua , Zheng Jing , Asiri Abdullah M. , Marwani Hadi M. , Xu Jingli , Zhang Min
Published: December 2017

This work develops an extended Stöber method to obtain SiO2@polydopamine with a one‐pot process. Such composites can be further processed to obtain hollow N‐doped carbon capsules (HNCSs). More importantly, the HNCSs can be used as templates to synthesise HNCSs@Fe3O4 and HNCSs@MnO2 composites, which greatly widened the application of HNCSs.
Material optimization for nonlinearly elastic planar beams
Authors: Hornung Peter , Rumpf Martin , Simon Stefan
Published: December 2017

We consider the problem of an optimal distribution of soft and hard material for nonlinearly elastic planar beams. We prove that under constant vertical load the optimal distribution involves no microstructure and is ordered, and we provide numerical simulations confirming and extending this observation.
Palliative Embolization for Refractory Bleeding
Authors: Niekamp Andrew , Sheth Rahul , Kuban Joshua , Avritscher Rony , Ganguli Suvranu
Published: December 2017

Bleeding is a common and often challenging complication of malignancy. Etiologies of hemorrhage in this patient population vary, and bleeding may present as an acute, life-threatening emergency or a chronic, low-volume blood loss. For patients with advanced malignancies, interventions to manage bleeding must be balanced by the patient's life expectancy and quality of life. As such, minimally invasive procedures such as transarterial embolization are useful therapeutic options in appropriately selected patients. There is a rich history of palliative transarterial embolization for refractory bleeding in cancer patients. This technique was first applied in the 1970s and has since become an established treatment tool for malignancy-related bleeding throughout the body. While the preponderance of published data comprised case reports and small retrospective studies, the use of embolization continues to expand as experience grows and techniques are refined. In this review, we summarize the literature and provide our perspective on embolization for refractory bleeding in cancer patients.
Sportverletzungen beim Hund – Häufige Probleme unserer
Hundesportler
Authors: Neumann Stephan
Published: December 2017

Hundesport erfreut sich zunehmender Beliebtheit. Doch die steigende Zahl sportlicher
Aktivitäten impliziert auch die Zunahme assoziierter Verletzungen. Im Beitrag sollen
beispielhaft einige Verletzungsrisiken, deren Diagnostik und Therapie vorgestellt
werden.
Risiken umschiffen
Authors: Ehrengruber Maximilian , Wurm Claudius
Published: December 2017

Risikokompass „Heute wurden Instrumente in einem falschen Container verpackt und keinem ist es aufgefallen.“ Kommen Ihnen solche oder
ähnliche Aussagen bekannt vor? Im OP und in der Medizinprodukteaufbereitung lauern zahlreiche Risiken, die es zu verhindern gilt. Unsere
Autoren haben deshalb eine Methode entwickelt, mit der das Risikomanagement für alle Mitarbeiter verständlich und leicht anwendbar ist: den
Risikokompass.
Sichere Begleitung für Siebe
Authors: Stark Uwe
Published: December 2017

Leihsiebe In der täglichen OP-Praxis, insbesondere in der Orthopädie und Unfallchirurgie, sind sie nicht mehr wegzudenken: Leihsiebe.
Damit alle Beteiligten den Überblick behalten, hat unser Autor einen internen Begleitschein für Leihsiebe und -implantate entwickelt, der
die Dokumentation erleichtert und ein strukturiertes und transparentes Vorgehen ermöglicht.
Standardisierte Medizin – der Weg in die Zukunft
Authors: Solcher Bertram
Published: December 2017

Digitalisierung Medizin 4.0 oder Robotermedizin – wie immer man die technisch unterstützten Arbeitsprozesse nennt, sie sorgen für
Skepsis. Dabei birgt der Trend großes Potenzial für Kliniken, außerdem setzt Digitalisierung dort an, wo es niemandem weh tut.
Vom Bildarchiv zum Informationspool
Authors: Kucera Martin
Published: December 2017

PACS-Systeme Die zunehmende Digitalisierung im Krankenhaus produziert immer mehr Bilder, Videos und elektronische Dokumente. Um dieser
Datenflut Herr zu werden, braucht es eine IT-Strategie. Die Anbieter setzten bei ihren PACS-Systemen auf größtmögliche Flexibilität.
Schuleingangsuntersuchung bei Seiteneinsteigenden – was kann, was soll sie leisten? Ein Diskussionsbeitrag auf Grundlage der Daten aus dem Gesundheitsamt Frankfurt am Main 2006–2016
Authors: Karathana Maria , Krackhardt Bernhard , Schade Manuela , Heudorf Ursel
Published: December 2017

Fragestellung Die Untersuchung der Schulanfänger ist eine der wesentlichen Aufgaben der Kinder- und Jugendärztlichen Dienste der Gesundheitsämter. Während in allen Bundesländern die Untersuchung aller Erstklässler vor Schuleintritt gesetzlich klar festgeschrieben ist, ist die Situation für Seiteneinsteigende, d.h. Kinder im schulpflichtigen Alter, die aus dem Ausland in eine Gemeinde zuziehen und dort eingeschult werden, in den meisten Schulgesetzen nicht eindeutig geregelt. In dem Beitrag werden die Erfahrungen aus den Seiteneinsteigenden-Untersuchungen in Frankfurt am Main geschildert.

Methode Alle aus dem Ausland nach Frankfurt zugezogenen Kinder im schulpflichtigen Alter werden im Gesundheitsamt untersucht. Diese Untersuchung umfasst eine mithilfe von Dolmetschern durchgeführte standardisierte fragebogengestützte Anamnese inkl. Durchsicht des ggf. vorhandenen Impfbuchs (Anamnesebögen sind in verschiedenen Sprachen vorhanden), einen Seh- und Hörtest sowie eine körperliche Untersuchung. Kinder über 15 Jahren, die aus Hochprävalenzländern für eine Tuberkulose kommen, wurden geröntgt (Röntgen-Thorax).

Ergebnisse Von 2006 bis Ende 2016 wurden insgesamt 8245 Kinder- und Jugendliche untersucht. Auffälligkeiten im Hörscreening wiesen 4% der Untersuchten auf, im Sehscreening 22% – mit steigender Tendenz in den letzten Jahren. Bei zwei Drittel der Kinder blieb der Impfstatus unbekannt, ein Viertel der Kinder war ausreichend gegen Tetanus, Diphtherie, Polio und Pertussis geimpft, 19,5% waren gegen Masern immun (geimpft oder durchgemachte Erkrankung). Bei der körperlichen Untersuchung dominierten Erkrankungen der Atemwege, des Herzens und des Kreislaufs mit insgesamt 4% vor den Muskel-Skeletterkrankungen mit 3%. Läusebefall wurde bei 1,7% der Kinder festgestellt. Bei 0,7% der 2171 geröntgten Kinder wurde ein auffälliger Lungenbefund ermittelt, in keinem einzigen Fall eine Tuberkulose.

Schlussfolgerung Fokus der Seiteneinsteigenden-Untersuchung ist ein schulbezogener Gesundheitsstatus. Auf Grundlage der Erfahrungen aus Frankfurt am Main ist festzustellen, dass die Untersuchung der aus anderen Ländern zugezogenen Seiteneinsteigenden sinnvoll erscheint, insbesondere das Seh- und Hörscreening, die körperliche Untersuchung und die Überprüfung des Impfstatus, ggf. mit Schließung der Impflücken. Demgegenüber erscheint eine ausführliche Entwicklungsdiagnostik bei den unmittelbar schulpflichtigen Kindern und damit bei fehlenden Fördermöglichkeiten vor Schulbeginn nicht vordringlich.
Neuraltherapie in Gynäkologie und Geburtshilfe
Authors: Bernert Klaus-Dieter
Published: December 2017

Die Neuraltherapie stellt ein Bindeglied zwischen Schul- und Komplementärmedizin dar. Die Behandlung mit Lokalanästhetika zielt darauf, sog.
Störfelder zu beseitigen und die körpereigene Regulationsfähigkeit wiederherzustellen.

Am Beispiel von Beschwerden in Schwangerschaft, Wochenbett und Gynäkologie werden bewährte Injektionstechniken und deren mögliche Erfolge
anhand von Fällen aus der Praxis des Autors vorgestellt.
Photoemission and photoionization time delays and rates
Authors: Gallmann L. , Jordan I. , Wörner H. J. , Castiglioni L. , Hengsberger M. , Osterwalder J. , Arrell C. A. , Chergui M. , Liberatore E. , Rothlisberger U. , Keller U.
Published: December 2017

Ionization and, in particular, ionization through the interaction with light play an important role in fundamental processes in physics, chemistry, and biology. In recent years, we have seen tremendous advances in our ability to measure the dynamics of photo-induced ionization in various systems in the gas, liquid, or solid phase. In this review, we will define the parameters used for quantifying these dynamics. We give a brief overview of some of the most important ionization processes and how to resolve the associated time delays and rates. With regard to time delays, we ask the question: how long does it take to remove an electron from an atom, molecule, or solid? With regard to rates, we ask the question: how many electrons are emitted in a given unit of time? We present state-of-the-art results on ionization and photoemission time delays and rates. Our review starts with the simplest physical systems: the attosecond dynamics of single-photon and tunnel ionization of atoms in the gas phase. We then extend the discussion to molecular gases and ionization of liquid targets. Finally, we present the measurements of ionization delays in femto- and attosecond photoemission from the solid–vacuum interface.