bluuebunny/crossref_metadata_2025 huggingface dataset:
Study on discriminant method of rock type for porous carbonate reservoirs based on Bayesian theory
Authors: Fang Xinxin , Feng Hong
Published: September 2021

Rock typing is an extremely critical step in the estimation of carbonate reservoir quality and reserves in the Middle East. In order to recognize the rock types of carbonate reservoirs in the Mishrif Formation better, classify the reservoirs accurately, and establish the permeability model in line with the study area precisely, it is necessary to study the recognition method conforming to the actual situation of the study area. The practice shows that the current recognition methods based on capillary pressure curve, flow unit and NMR logging data can effectively distinguish rock types, but a large number of accurate experimental data are required, which can only be applied in a few cored well, however, cannot be applied in the whole oil field. In this study, based on core, thin section, logging data, the sedimentary characteristics of carbonate reservoir, logging response of four rock types as well as porosity and permeability characteristics of Mishrif Formation in W are comprehensively studied. Based on Bayesian stepwise discriminant theory in multivariate statistics, the Bayesian discrimination model based on conventional logging data is established. The examining results showed that, compared with the description of logging and coring, the accuracy of Bayesian discriminant model and cross confirmation rate have achieved more than 80% for the original sample. Reliability verification showed that the matching degree of the rock type recognized in the non-cored well with the core and mud logging was as high as 90%, which matched the depositional environment of the entire region. The study results confirm the validity and generalizability of the Bayesian method to identify and predict rock types, which can be applied to the entire Middle East region to solve the problem of the lack of core data to accurately evaluate the quality of non-cored wells and accurately predict production, meeting the needs of actual reservoir evaluation and production development in the Middle East.
Relative risk of functional dyspepsia in patients with sleep disturbance: a population-based cohort study
Authors: Su Hsu-Han , Sung Fung-Chang , Kao Kai-Liang , Chen Shu-Chin , Lin Chen-Ju , Wu Shu-I , Lin Cheng-Li , Stewart Robert , Chen Yi-Shin
Published: September 2021

Increased prevalence of sleep disorders has been found in patients with functional dyspepsia; however, direction of causality remains unclear. Our aim was to compare the risk of incident functional dyspepsia between patients with and without sleep disturbance from a large population-based sample. Utilizing a nation-wide health insurance administrative dataset, we assembled an 11-year historic cohort study to compare subsequent incidence of diagnosed functional dyspepsia between adult patients with any diagnosis of sleep disturbance and age- and gender-matched controls. Hazard ratios adjusted for other relevant comorbidities and medications were calculated using Cox regression models. 45,310 patients with sleep disorder and 90,620 controls were compared. Patients with sleep apnea had a 3.3-fold (95% confidence interval: 2.82 ~ 3.89) increased hazard of functional dyspepsia compared with controls. This increased risk persisted regardless of previously diagnosed depression coexisted. Sleep disturbance was associated with an increased risk of subsequent functional dyspepsia. Potential mechanisms are discussed.
Simulation studies on electrical characteristics of silicon nanowire feedback field-effect transistors with interface trap charges
Authors: Yang Yejin , Park Young-Soo , Son Jaemin , Cho Kyoungah , Kim Sangsig
Published: September 2021

In this study, we examine the electrical characteristics of silicon nanowire feedback field-effect transistors (FBFETs) with interface trap charges between the channel and gate oxide. The band diagram, I–V characteristics, memory window, and operation were analyzed using a commercial technology computer-aided design simulation. In an n-channel FBFET, the memory window narrows (widens) from 5.47 to 3.59 V (9.24 V), as the density of the positive (negative) trap charges increases. In contrast, in the p-channel FBFET, the memory window widens (narrows) from 5.38 to 7.38 V (4.18 V), as the density of the positive (negative) trap charges increases. Moreover, we investigate the difference in the output drain current based on the interface trap charges during the memory operation.
DEVOLUTION—A method for phylogenetic reconstruction of aneuploid cancers based on multiregional genotyping data
Authors: Andersson Natalie , Chattopadhyay Subhayan , Valind Anders , Karlsson Jenny , Gisselsson David
Published: September 2021

Phylogenetic reconstruction of cancer cell populations remains challenging. There is a particular lack of tools that deconvolve clones based on copy number aberration analyses of multiple tumor biopsies separated in time and space from the same patient. This has hampered investigations of tumors rich in aneuploidy but few point mutations, as in many childhood cancers and high-risk adult cancer. Here, we present DEVOLUTION, an algorithm for subclonal deconvolution followed by phylogenetic reconstruction from bulk genotyping data. It integrates copy number and sequencing information across multiple tumor regions throughout the inference process, provided that the mutated clone fraction for each mutation is known. We validate DEVOLUTION on data from 56 pediatric tumors comprising 253 tumor biopsies and show a robust performance on simulations of bulk genotyping data. We also benchmark DEVOLUTION to similar bioinformatic tools using an external dataset. DEVOLUTION holds the potential to facilitate insights into the development, progression, and response to treatment, particularly in tumors with high burden of chromosomal copy number alterations.
Size and profile of skyrmions in skyrmion crystals
Authors: Wu Haitao , Hu Xuchong , Jing Keyu , Wang X. R.
Published: September 2021

Size is a fundamental quantity of magnetic skyrmions. A magnetic skyrmion can be a local circular object and in an isolated form. A skyrmion can also coexist with a group of its siblings in a condensed phase. Each skyrmion in a condensed phase takes a stripe shape at low skyrmion density and a circular shape at high skyrmion density. Skyrmions at high density form a skyrmion crystal (SkX). So far, skyrmion size in an SkX has not been seriously studied. Here, by using a generic chiral magnetic film, it is found that skyrmion size in an SkX has a different parameter dependence as those for isolated skyrmions and stripes. A size formula and a good spin profile for skyrmions in SkXs are proposed. These findings have important implications in searching for stable smaller skyrmions at the room temperature.
Interrogating cardiac muscle cell mechanobiology on stiffness gradient hydrogels
Authors: Chin Ian L. , Hool Livia , Choi Yu Suk
Published: September 2021

Mechanobiology of H9C2 cells and neonatal cardiomyocytes mapped using stiffness gradient hydrogels with a range of extracellular matrix coatings, revealing stiffness-driven trends in cell morphology, YAP and MRTF-A expression.
Hydroxy acid-functionalized ionic liquids as green alternatives for the efficient catalytic conversion of epoxides to cyclic carbonates under solvent and co-catalyst-free conditions
Authors: Yue Shuang , Qu Hongliu , Song Xinxin , Zang Shuliang , Deng Guichun
Published: September 2021

Environmentally friendly synthesis route of carbonates from CO2 and epoxides catalysed by novel hydroxy acid ionic liquids under metal/halogen/cocatalyst/solvent-free conditions.
Molecular mechanism of enhancing the immune effect of the Newcastle disease virus vaccine in broilers fed with Bacillus cereus PAS38
Authors: Li Wanqiang , Li Jianzhen , He Nianjia , Dai Xixi , Wang Zhenhua , Wang Yufei , Ni Xueqin , Zeng Dong , Zhang Dongmei , Zeng Yan , Pan Kangcheng
Published: September 2021

The aim of this study was to explore the molecular mechanism of enhancing the immune effect of the Newcastle disease virus (NDV) vaccine in broilers fed with Bacillus cereus PAS38.
Functionalized silica nanoplatform as a bimodal contrast agent for MRI and optical imaging
Authors: Garifo Sarah , Stanicki Dimitri , Boutry Sébastien , Larbanoix Lionel , Ternad Indiana , Muller Robert N. , Laurent Sophie
Published: September 2021

The preparation of an efficient bimodal single probe for magnetic resonance (MRI) and optical imaging (OI) is reported.
Catalyst-controlled switchable [4 + 1], [4 + 3] and [3 + 2] domino reactions of azadienes and MBH carbonates: diverse synthesis of benzothiophene fused derivatives
Authors: Zeng Wenlei , Yu Aimin , Meng Xiangtai
Published: September 2021

Catalyst-controlled switchable [4 + 1], [4 + 3], and [3 + 2] domino reactions between azadienes bearing a benzothiophene moiety and isatin-derived MBH carbonates were developed.
Composite clusters: Co5.7Ni2.3W12O42(OH)4@fluoro-graphdiyne as a stable electrode for sustained electrochemical oxygen evolution under high current conditions
Authors: Sun Hao , Xu Xiaomei , Jing Chaojun , Shang Wenhui , Wang Yongchun , Zeng Muling , Jia Zhiyu
Published: September 2021

A composite cluster [Co5.7Ni2.3W12O42(OH)4@FGDY] exhibited high performance for the electrochemical oxygen evolution reaction with low potentials at high current density and long stability.
Theoretical evaluation of the performance of IRMOFs and M-MOF-74 in the formation of 5-fluorouracil@MOF
Authors: Rodrigues Nailton M. , Martins João B. L.
Published: September 2021

Drug delivery systems are a viable resource to be used in medical treatments that tend to be very aggressive to patients, increasing the bioavailability.
Discovery of 8-prenylnaringenin from hop (Humulus lupulusL.) as a potent monoacylglycerol lipase inhibitor for treatments of neuroinflammation and Alzheimer's disease
Authors: Tung Min-Che , Fung Kit-Man , Hsu Hsin-Mie , Tseng Tien-Sheng
Published: September 2021

Discovery of natural product inhibitors against human monoacylglycerol lipase by pharmacophore-based drug screening, LibDock molecular docking andin vitrobiochemical examinations.
First-principles study of Mn3 adsorbed on Au(111) and Cu(111) surfaces
Authors: Hernández-Vázquez E. E. , López-Moreno S. , Munoz F. , Ricardo-Chavez J. L. , Morán-López J. L.
Published: September 2021

Adsorption energy difference of Mn trimer on Au(111) and Cu(111) surfaces as a function of the magnetic state configuration. Where, the lowest energy state is the AFΔ one.
Electrospinning preparation and near-infrared absorption properties of a silica/cesium tungsten bronze micro–nano fiber membrane
Authors: Song Yilong , Zhao Fang , Li Zhizun , Cheng Zhaogang , Wan Hongjing
Published: September 2021

A silica/cesium tungsten bronze composite fiber membrane with good near-infrared shielding performance is prepared by electrostatic spinning, and can be used for solar heat insulation.
Topological signatures and stability of hexagonal close packing and Barlow stackings
Authors: Osang Georg , Edelsbrunner Herbert , Saadatfar Mohammad
Published: September 2021

3D rendering of the experimental packing obtained via X-ray CT. A cut-out section shows the bulk crystallisation and partially crystallised regions.
Enhanced ionic transport in ferroelectric polymer fiber mats
Authors: Sultana Ayesha , Alam Md. Mehebub , Fabiano Simone , Crispin Xavier , Zhao Dan
Published: September 2021

The electrospun induced ferroelectric β-phase in a polymer mats is proven to enhance the ionic conductivity. This finding enables the demonstration of the first ionic thermistor and could inspire the development of solid-state electrolytes.
Insights into the electronic structure of Fe penta-coordinated complexes. Spectroscopic examination and electrochemical analysis for the oxygen reduction and oxygen evolution reactions
Authors: Loyola César Zúñiga , Abarca Gabriel , Ureta-Zañartu Soledad , Aliaga Carolina , Zagal Jose H. , Sougrati Moulay Tahar , Jaouen Frédéric , Orellana Walter , Tasca Federico
Published: September 2021

Fe penta-coordinated complexes are exceptionally good electrocatalysts for the oxygen reduction and evolution reactions. Spectroscopical and electrochemical studies show the reasons.
Suppression of dendritic lithium-metal growth through concentrated dual-salt electrolyte and its accurate prediction
Authors: Vu Tai Thai , Kim Byung Gon , Kim Jung Ho , Moon Janghyuk
Published: September 2021

The utilization of lithium (Li) Metal is highly desirable, because it is the most attractive anode for high-energy Li batteries, even if there are problems with the unpredictable phenomena of dendritic Li growth during repeated plating-stripping.
A synopsis of progressive transition in precursor inks development for metal halide perovskites-based photovoltaic technology
Authors: Thi Kim Cuc Mai , Atourki Lahoucine , Ouafi Mouad , Hashmi Syed Ghufran
Published: September 2021

Precursor inks development contributed significantly to rapid escalations in solar-to-electrical conversion efficiencies of peorvskite solar cell technology.
High-throughput screening of TMOCl cathode materials based on the full-cell system for chloride-ion batteries
Authors: Wu Mengqi , Lv Xiaohuan , Wang Jianglong , Wang Ruining , Shi Xingqiang , Zhang Hu , Jin Chendong , Wei Yingjin , Lian Ruqian
Published: September 2021

Discharge of the Li–CoOCl full-cell system and the Cl− migration path in CoOCl.
Performance and durability of anion exchange membrane water electrolyzers using down-selected polymer electrolytes
Authors: Motz Andrew R. , Li Dongguo , Keane Alex , Manriquez Luis Delfin , Park Eun Joo , Maurya Sandip , Chung Hoon , Fujimoto Cy , Jeon Jongyeob , Pagels Michael K. , Bae Chulsung , Ayers Katherine E. , Kim Yu Seung
Published: September 2021

We investigated how chemical structure and physical properties of polymer electrolytes affect performance and durability of anion exchange membrane water electrolyzers.
A high-performance cathode for potassium-ion batteries based on uniform P3-type K0.5Mn0.8Co0.1Ni0.1O2porous microcuboids
Authors: Duan Liping , Xu Yifan , Zhang Zhuangzhuang , Xu Jingyi , Liao Jiaying , Xu Jianzhi , Sun Yingying , He Yanan , Zhou Xiaosi
Published: September 2021

Uniform P3-type K0.5Mn0.8Co0.1Ni0.1O2porous microcuboids are prepared by a low-cost ethanol mediated coprecipitation strategy, exhibiting improved potassium storage properties.
Reducing the leakage current for a CsPbBr3 detector via asymmetric area electrodes and heterostructures
Authors: Ruan YingFeng , Guo Pengju , Zheng Zhiping , Fu Qiuyun , Zhou Rongda , Chen Hualin , Wang Geng , Luo Wei
Published: September 2021

As a typical representative of all-inorganic lead halide perovskites, cesium lead bromine (CsPbBr3) has been regarded as the workhorse of next-generation room temperature X-ray detectors in recent years.
Epitaxial growth of β-Ga2O3 (−201) thin film on four-fold symmetry CeO2 (001) substrate for heterogeneous integrations
Authors: Tang Xiao , Li Kuang-Hui , Liao Che-Hao , Zheng Dongxing , Liu Chen , Lin Rongyu , Xiao Na , Krishna Shibin , Tauboada Jose , Li Xiaohang
Published: September 2021

High quality (−201) orientated β-Ga2O3 thin films are obtained on four-fold symmetric cubic phase CeO2 (001) substrates and are fabricated into photodetectors with excellent photoelectrical performance.
High-quality two-dimensional tellurium flakes grown by high-temperature vapor deposition
Authors: Huang Baoquan , Lei Zehong , Cao Xuanhao , Wei Aixiang , Tao Lili , Yang Yibin , Liu Jun , Zheng Zhaoqiang , Zhao Yu
Published: September 2021

Large-area and high-quality 2D Te flakes were synthesized by high-temperature vapor deposition using In2Te3 powder as source. The thin Te flakes exhibit low electrical resistivity, high hole mobility and ultrahigh photoresponsivity in visible range.
A thermally robust and optically transparent infrared selective emitter for compatible camouflage
Authors: Zhang Lei , Wang Jun , Lou Jing , Zhu Ying , Gui Boheng , Feng Mingde , Wang Jiafu , Qu Shaobo
Published: September 2021

The proposed ITO/ZnS/ITO/ZnS composite film is simple in geometry, functional in use, but complex in mechanism, which may promote its pratical application in infrared-visible compatible camouflage.
Comprehensive Raman study of orthorhombic κ/ε-Ga2O3and the impact of rotational domains
Authors: Janzen Benjamin M. , Mazzolini Piero , Gillen Roland , Peltason Vivien F. S. , Grote Linus P. , Maultzsch Janina , Fornari Roberto , Bierwagen Oliver , Wagner Markus R.
Published: September 2021

The Raman-active phonon modes of orthorhombic gallium oxide (κ/ε-Ga2O3) are investigated by combination of polarized micro-Raman spectroscopy and density functional perturbation theory (DFPT) calculations.
Modelling and analysis of half‐/full‐bridge hybrid MMC when riding through DC‐side pole‐to‐ground fault
Authors: He Zhen , Hu Jiabing , Lin Lei , Zeng Pingliang
Published: September 2021

In a modular multilevel converter‐based high‐voltage direct current (MMC‐HVDC) system, the dc fault ride through (FRT) control is an effective way to deal with a dc‐side pole‐to‐ground (PTG) fault. However, the setting of FRT duration brings potential hazards: 1) MMC will face the risk of “secondary short circuit” if FRT duration is short; 2) ac grid may have power angle stability issue if FRT duration is long. To avoid these hazards and provide theoretical guidance for the FRT duration setting, transient behaviour of dc fault current during the PTG FRT stage is explored in this work. Firstly, challenges of the transient analysis are summarised as non‐linearity and high‐order issues. In light of this, numerical and Hilbert‐Huang Transformation methods are introduced to evaluate the non‐linearity issue. It is found that the path of MMC from dc current to dc internal voltage is weakly non‐linear. Hence, a linear transient model is built to analyse the dc fault current. By participation factor analysis, the order of the proposed model is further reduced, so that an analytical expression of the dc fault current is approximately derived. Based on the analytical expression, regularities and mechanism of dc fault current are fully revealed. Application of the transient analysis to the setting of FRT duration is elaborated in detail. Finally, the PSCAD/EMTDC simulation verifies the validity of the proposed model and analytical expression.
LMI‐based passivation of LTI systems with application to marine structures
Authors: Faedo Nicolás , Peña‐Sanchez Yerai , Carapellese Fabio , Mattiazzo Giuliana , Ringwood John V.
Published: September 2021

Due to the inherent relevance of passive (physically representative) models for control, state‐estimation, and motion simulation in the field of marine systems, in this paper, an optimisation‐based approach to passivation of linear time‐invariant (LTI) systems is proposed with application to physically consistent dynamical modelling of marine structures. In particular, the presented strategy is based upon the introduction of a suitably designed perturbation, computed via minimisation of a linear objective subject to a specific set of linear matrix inequalities (LMIs). The performance of the passivation technique is showcased in terms of two case studies: An offshore platform, with a frequency‐domain response computed by means of hydrodynamic codes, and a 1:20 scale wave energy converter (WEC), is characterised in terms of real experimental data.
An embedded discontinuous Galerkin method for the Oseen equations
Authors: Han Yongbin , Hou Yanren
Published: September 2021

In this paper, thea priorierror estimates of an embedded discontinuous Galerkin method for the Oseen equations are presented. It is proved that the velocity error in theL2(Ω) norm, has an optimal error bound with convergence orderk + 1, where the constants are dependent on the Reynolds number (orν−1), in the diffusion-dominated regime, and in the convection-dominated regime, it has a Reynolds-robust error bound with quasi-optimal convergence orderk + 1/2. Here,kis the polynomial order of the velocity space. In addition, we also prove an optimal error estimate for the pressure. Finally, we carry out some numerical experiments to corroborate our analytical results.
Features of the concept of happiness representation in PR discourse
Authors: Minyar-Beloroucheva Alla Petrovna , Sergienko Polina Igorevna , Vishnyakova Olga Dmitrievna , Vishnyakova Elizaveta Alexandrova , Knyazhinskaya Elena Viktorovna
Published: September 2021

The article deals with the concept of HAPPINESS in Public Relation discourse (PR discourse). The concept of HAPPINESS refers to one of the most important components of the linguistic worldview of each nation. Analysis of lexical units that verbalize the concept of HAPPINESS through the prism of PR discourse allows us to identify the linguistic features that create images contributing to the promotion of various ideas of PR campaigns especially dealing with food promotion. The desire to be happy is inherent in every person as an integral part of his or her nature. The persons’ ideas concerning happiness are included in the life system of their values and express their attitude to the world. The problem of human happiness has long been the most important issue of philosophy but presently of some transdisciplinary areas, PR campaigns included. The conducted study shows that happiness as the supreme good, as the possible and achievable state of human existence, is one of the main concerns of PR discourse. At present the interest in the concept of happiness and how to achieve it is of primary importance for PR councilors, responsible for the goodwill of their companies in the long run. Both at its associative level and linguistically it is achieved by means of connotatively loaded lexical units denoting taste and strong emotions, necessary for the empirical construction of happiness.
The phenomenon of happiness in the Muslim tradition
Authors: Senyutkina Olga Nikolaevna
Published: September 2021

The need for research in the field of the designated problems is determined by the changing circumstances of the life of modern society on a global scale. In recent years, interfaith interactions in the world have not inspired optimism on improving intercultural contacts (one can mention the rejection of the policy of multiculturalism in Western Europe, terrorist attacks in France and other places, conflicts in the Middle East, etc.). The modern world demonstrates a blatant misunderstanding of others by social communities and the increasing conflict nature of the social environment. Hence the importance of academic developments of a humanistic nature. The author’s goal is to show the general and specific understanding of the phenomenon of happiness in Muslim culture. The Muslim tradition sees the happiness of a Muslim in a deep faith in Allah and adherence to a behavioral model, the example of which is the Prophet Muhammad. It is in the observance of Sharia law that lies the foundation of stability in the life of the global ummah (Muslim community) itself, as well as its relations with the outside world. The work methods for this paper were, first of all, a content analysis of Muslim texts, a review of the historiography of the problem of understanding of happiness by Muslims, as well as direct contact with the Nizhny Novgorod Muslim Tatars during field studies expressed in in-depth interviews (1995–2000). The novelty of the work lies in the choice of the Muslim discourse of understanding happiness as the object of the author’s consideration. As a result of the study, the author comes to confirm the idea that knowledge about the worldview attitudes of other cultures can help relieve tension in human communications at different levels. The data stated above are a confirmation of the Qur’anic tradition of finding means for peaceful communication between different ethnicities, as well as the works of Muslim scholars aimed at establishing good neighbor relationships in strengthening intercultural communication.
The level of aspiration as an indicator of a person’s desire for financial well-being
Authors: Shneyder Lidiya Berngardovna , Egorov Ilia Vladimirovich , Kozintseva Polina Alexandrovna
Published: September 2021

The mobility of the modern world generates interest not only in innovative technologies but also in workers themselves, the assessment of their level of aspiration. Consequently, the level of aspiration falls into the zone of research interest and should be considered as a significant factor of human practical activity. It can be studied through diagnostic procedures aimed at identifying the structural and content components free of the professional subject orientation. This corresponds to the study of the level of aspiration on the material of aspiration for financial well-being. The conducted empirical study explores the characteristics of the level of ambition including a focus on the goal, monetary motivation, professional preferences, assessment of personal resources and capabilities. The study sample consists of 42 budgetary workers at the average age of 35. The overall direction and purpose of the empirical study are associated with revealing the characteristics of the level of ambition and its interrelation with Homo faber’s desires and expectations, motivational and personal characteristics, value orientations, and focus on the goal. The primary research method is a written questionnaire (a survey). Goal orientations are found to be quite strongly expressed in the studied sample, the respondents have developed self-respect and are not inclined to shift the blame to external circumstances but lack ambition. It is revealed that a budgetary worker desires financial well-being and high income and does not mind getting rich but is not ready to change themselves and compromise the established norms of a stable life. The level of aspiration is found to be “split”: the set objective goals are low compared to higher ones kept to oneself.
Reflexive positioning approach to the study of felicity and representations of happiness in the digital era
Authors: Kovaleva Natalia B. , Minaev Vitaliy R. , Zueva Anna V. , Novozhilova Lyubov
Published: September 2021

The article is devoted to the analysis of perceptions of what it means to be happy among modern Russians. The main focus of the study is to identify the level of subjective well-being of the respondents in association with their worldview ideas about happiness and the image of the world in representatives of different age groups. The paper gives a brief overview of the main studies of felicity, the concept of happiness, and subjective well-being. Based on the theoretical analysis of conceptual developments concerning the stages of development of moral consciousness, the value and meaning component of the image of the world, and the factors of subjective well-being, several models of happiness are constructed based on the results of content analysis and reflexive positioning analysis of the respondents’ reflections. The research targets also include the ratio of the scales of subjective well-being (SW) and subjective happiness (SH) or felicity and the nature of subjective satisfaction depending on the value-semantic model of ideas about happiness and the established image of the world. The study uses the methods of theoretical analysis and conceptual modeling, content analysis, and reflexive positional analysis of the text, a questionnaire including the scales of SW, SH, reflection on happiness, and the author’s value-meaning diagnostic complex. The noteworthy results substantiating the novelty of the study show that: 1) The level of the subjective happiness scale is higher than the SB scale and shows a more positive orientation; 2) The respondents with the religious and existential models of happiness were the happiest based on the scales of subjective well-being and subjective happiness; the respondents with the consumer model of happiness were the least happy. Two new opportunities emerge from the point of further research prospects and the practice of psychological counseling and psychotherapy. First, there is an opportunity to diagnose the presence and nature of an intra-personal conflict in the presence of a notable gap between the values on the SW and SH scales. Second, it is possible to identify the reasons for deficits and the direction of development based on reflexive positioning analysis of free reflections on happiness.
Features of emotional burnout syndrome in government employees
Authors: Maltseva Tatyana Vyacheslavna , Sumina Ekaterina Anatolyevna , Gorach Nikolai Nikolaevich , Khmelev Sergey Alexandrovich , Kovrova Vera Gennadievna
Published: September 2021

The problem of the onset, formation, and development of the phenomenon of emotional burnout is relevant in the study of any profession and is an important component for the professional activity of government employees in the Russian Federation. To explore the features of emotional burnout syndrome development in government employees and develop psychological recommendations for its prevention. Psychological testing of government employees and comparative analysis of the obtained results by groups; statistical processing of the obtained results. The study uses the method for diagnosing the emotional burnout level by V.V. Boyko. The experimental groups in the study are formed by 35 government employees who used to hold managerial positions (over 10 years of experience in civil service). The results of the study broaden the understanding of the place of emotional burnout syndrome in the professional activity of government employees. The features and mechanisms lying at the basis of the emergence and development of emotional burnout syndrome in civil servants are described. Ensuring government employees’ effectiveness in their duties calls for conducting a set of measures to reduce emotional burnout: optimization of the organization of activities, a favorable social and psychological climate in the team, and organized work of the psychological service. In the process of selection and training of government employees, it appears reasonable to pay attention to the individual characteristics preventing professional deformation and promote the development of the personal ability to withstand stressors (self-efficacy, confidence in the level of one’s professionalism, developed success goals; tolerance for difficulties and unpredictable situations; self-respect, an adequate level of self-esteem; resilience, the ability to manage professional affairs; the development of individual strategies for coping with stress, etc.).
The Reform of Blended Courses for Software Project Management
Authors: Li Liping , Wang Na
Published: September 2021

Blended teaching is a teaching method integrating classroom teaching and online learning. Based on OBE (Outcome-based education), this paper proposes some reform ideas for blended teaching by software project management curriculum. Project driven, flipped classroom, vivid animations, MOOC video and cases study etc. are adopted to improve the self-study ability and team work of students. Although it takes more time to study, it gain high praise and enhance the teaching quality.
Analyse des besoins en éducation thérapeutique de jeunes porteurs de déficience visuelle suivis dans un dispositif d’accompagnement adapté
Authors: Geisler Donatile , Clement Céline , Citarelli Florian
Published: September 2021

Tandis que le taux de chômage des personnes porteuses de handicap est plus élevé que celui de la population générale, des études récentes sur l’orientation professionnelle des personnes porteuses de handicap visuel ont montré l’importance de bien se connaître pour mieux comprendre et expliquer sa pathologie en milieu scolaire et professionnel, alors même que ce besoin ne semble pas perçu à l’adolescence. Ainsi, l’objectif du présent travail de recherche est de préciser les connaissances et besoins perçus en éducation thérapeutique des jeunes présentant une déficience visuelle. Pour ce faire une méthodologie qualitative est proposée en croisant les regards de jeunes adultes sortis des dispositifs d’accompagnements et de parents de jeunes porteurs de déficience visuelle. Ce sont sept jeunes adultes et quatre parents qui ont été interrogés. Les résultats montrent des besoins en éducation thérapeutique, la plupart émergeant a posteriori sur plusieurs thématiques, partagées entre jeunes adultes et parents.
Percutaneous CT Guided Vertebral Biopsy: Anatomy and Technical Considerations
Authors: Gala Kunal Bharat , Shetty Nitin S. , Janu Amit Kumar , Shetty Neeraj , Kulkarni Suyash S.
Published: September 2021

In this review article, the authors discuss the anatomy and technical aspects of CT-guided biopsy of vertebral lesions. CT guidance is highly useful for vertebral biopsies, as the anatomy of the spine is complex and varies widely across the levels. Prebiopsy imaging should be reviewed and later correlated with the final histopathological diagnosis. The majority of the spine biopsies are performed under local anesthesia, except those in critical locations and pediatric age groups. The biopsy sample is sent for histopathological analysis and/or microbiological analysis depending on the indications. It is preferable to use a coaxial system for biopsies, so multiple cores can be obtained with a single needle puncture, thus minimizing the negative yield and complications. Complications after image-guided percutaneous biopsy are rare and can be managed easily.
N-Butyl Cyanoacrylate Embolization in Management of Iatrogenic Renal Hemorrhages—Single-Center Study Evaluating Safety and Efficacy
Authors: Narkhede Amey , Yadav Ajit Kumar , Gupta Arun
Published: September 2021

Objectives The aim of the study was to evaluate the efficacy of endovascular N-butyl cyanoacrylate (NBCA)/glue embolization alone in the management of iatrogenic renal injuries and its effect on renal function.

Methods Thirty-one patients who presented with significant iatrogenic renal injuries over a time period ranging from June 2013 to June 2018 were evaluated. The clinical features, lab parameters, and imaging findings were recorded. The embolizing agent used was exclusively NBCA. The success rate was calculated along with the effect of glue embolization on kidney in the form of postembolization ischemia and change in the serum creatinine levels in immediate pre- and postembolization period. The time between the iatrogenic injury and angioembolization as well as the time from angioembolization to discharge was also calculated. Recurrence was evaluated at 1 and 6 months follow-up.

Results NBCA embolization showed 100% technical and clinical success in our study and no recurrence was noted at follow-up. Glue was also able to achieve complete embolization in patients with coagulopathy (n = 14, 45.1%). Percentage area deficit of normal renal blush in the postembolization check angiogram varied from 4 to 15.7% with a mean deficit of 7.65%. No significant difference in the serum creatinine was noted in immediate postembolization period.

Conclusions We conclude that glue is an effective embolizing agent for management of iatrogenic renal injuries even in coagulopathy patients with minimal area of parenchymal loss, no significant effect on renal functions, and no recurrence on 6 months follow-up.
Optimizing Fluid Resuscitation and Preventing Fluid Overload in Patients with Septic Shock
Authors: Ravi Chandni , Johnson Daniel W.
Published: September 2021

Intravenous fluid administration remains an important component in the care of patients with septic shock. A common error in the treatment of septic shock is the use of excessive fluid in an effort to overcome both hypovolemia and vasoplegia. While fluids are necessary to help correct the intravascular depletion, vasopressors should be concomitantly administered to address vasoplegia. Excessive fluid administration is associated with worse outcomes in septic shock, so great care should be taken when deciding how much fluid to give these vulnerable patients. Simple or strict “recipes” which mandate an exact amount of fluid to administer, even when weight based, are not associated with better outcomes and therefore should be avoided. Determining the correct amount of fluid requires the clinician to repeatedly assess and consider multiple variables, including the fluid deficit, organ dysfunction, tolerance of additional fluid, and overall trajectory of the shock state. Dynamic indices, often involving the interaction between the cardiovascular and respiratory systems, appear to be superior to traditional static indices such as central venous pressure for assessing fluid responsiveness. Point-of-care ultrasound offers the bedside clinician a multitude of applications which are useful in determining fluid administration in septic shock. In summary, prevention of fluid overload in septic shock patients is extremely important, and requires the careful attention of the entire critical care team.
Clinical Spectrum of TGM6-Related Movement Disorders: A New Report with a Pooled Analysis of 48 Patients
Authors: Sharawat Indar Kumar , Panda Prateek Kumar , Bhunia Niladri Sekhar , Dawman Lesa
Published: September 2021

Background Spinocerebellar ataxias (SCAs) are a diverse group of progressive neurodegenerative disorders. Until now, more than 20 genes have been implicated to be associated with this phenotype and TGM6 is one of these genes, associated with spinocerebellar ataxia-35 (SCA-35). The majority of disease-causing variants in the TGM6 gene predominantly have been reported from China and Taiwan and the association with Parkinson's disease (PD) have also been reported recently.

Methods We report the first Indian case with SCA-35 in a 16-year-old-boy with atypical age of onset at 9 years, prominent extrapyramidal features, intellectual disability, and a novel missense mutation in the TGM6 gene. We also reviewed and collated all previously published cases with pathogenic TGM6 variants.

Results Including the index case, 54 cases were identified from 10 relevant articles in literature and 48 cases had adequate clinical details to be included in the pooled analysis. Around two-thirds of reported cases had SCA-35 phenotype, with cerebellar atrophy. Onset in the majority of cases was the fourth decade of life onwards. A proportion of SCA-35 cases also had spasmodic torticollis, impaired proprioception, extrapyramidal features, and myoclonic jerks. The patients with PD had often early-onset milder symptoms, slower progression, and favorable response to levodopa/carbidopa. One patient each presented with episodic ataxia and dystonic tremor of the upper limb. Most of the cases had missense mutations, without any definite hotspot or genotype–phenotype correlation.

Conclusions TGM6 mutation should be suspected in patients with SCA like presentation, especially when it is accompanied by extrapyramidal features, spasmodic torticollis, impaired proprioception, or myoclonus.
The Triad of Cognition, Language, and Communication in Traumatic Brain Injury: A Correlational Study
Authors: Darshini Jeevendra Kumar , Afsar Mohammed , Vandana Valiyaparambath Purushothaman , Shukla Dhaval , Rajeswaran Jamuna
Published: September 2021

Objectives Traumatic brain injury (TBI) is associated with deficits in cognition, language, and communication along with physical and psychosocial consequences. This study aimed at evaluating the association between cognition, language, and communication in a cohort of patients with TBI in southern India using standardized language specific assessment tools.

Materials and Methods The present correlational study included 30 patients with TBI of any severity, that is, mild, moderate, and severe within the postinjury period of 6 to 36 months. Comprehensive evaluation of cognition, language, and communication was done using National Institute of Mental Health and Neurosciences Neuropsychology Battery, Indian adapted versions of Western Aphasia Battery and La Trobe Communication Questionnaire (LCQ) respectively.

Data Analysis Measures of descriptive statistics, that is, mean, median, percentages, and frequencies, were used. Raw scores, that is, aphasia quotient (AQ), and subdomain scores for LCQ, that is, LCQ-quality, quantity, relation, manner, and cognition, were calculated. Composite scores for the three neuropsychological domains, that is, attention and processing speed, executive function, learning and memory, were evaluated. Partial correlation was computed for identifying the association between the three variables by controlling for age, education, duration, and severity of injury.

Results A significant correlation was found between AQ and measures of attention and executive functioning and all measures of LCQ except LCQ-manner. Further, a significant correlation was found between executive functioning and LCQ-total, LCQ-quantity, and LCQ cognition. No correlation was found between measures of attention and memory with communication.

Conclusion A good language and executive functioning are associated with better communication abilities in patients with TBI thus emphasizing on the importance of a multidisciplinary team for the management of cognitive-communication impairments following a TBI.
Estimating Bleeding Risk in Patients with Cancer-Associated Thrombosis: Evaluation of Existing Risk Scores and Development of a New Risk Score
Authors: de Winter Maria A. , Dorresteijn Jannick A. N. , Ageno Walter , Ay Cihan , Beyer-Westendorf Jan , Coppens Michiel , Klok Frederikus A. , Moustafa Farès , Riva Nicoletta , Ruiz Artacho Pedro C. , Vanassche Thomas , Nijkeuter Mathilde
Published: September 2021

Background Bleeding risk is highly relevant for treatment decisions in cancer-associated thrombosis (CAT). Several risk scores exist, but have never been validated in patients with CAT and are not recommended for practice.

Objectives To compare methods of estimating clinically relevant (major and clinically relevant nonmajor) bleeding risk in patients with CAT: (1) existing risk scores for bleeding in venous thromboembolism, (2) pragmatic classification based on cancer type, and (3) new prediction model.

Methods In a posthoc analysis of the Hokusai VTE Cancer study, a randomized trial comparing edoxaban with dalteparin for treatment of CAT, seven bleeding risk scores were externally validated (ACCP-VTE, HAS-BLED, Hokusai, Kuijer, Martinez, RIETE, and VTE-BLEED). The predictive performance of these scores was compared with a pragmatic classification based on cancer type (gastrointestinal; genitourinary; other) and a newly derived competing risk-adjusted prediction model based on clinical predictors for clinically relevant bleeding within 6 months after CAT diagnosis with nonbleeding-related mortality as the competing event (“CAT-BLEED”).

Results Data of 1,046 patients (149 events) were analyzed. Predictive performance of existing risk scores was poor to moderate (C-statistics: 0.50–0.57; poor calibration). Internal validation of the pragmatic classification and “CAT-BLEED” showed moderate performance (respective C-statistics: 0.61; 95% confidence interval [CI]: 0.56–0.66, and 0.63; 95% CI 0.58–0.68; good calibration).

Conclusion Existing risk scores for bleeding perform poorly after CAT. Pragmatic classification based on cancer type provides marginally better estimates of clinically relevant bleeding risk. Further improvement may be achieved with “CAT-BLEED,” but this requires external validation in practice-based settings and with other DOACs and its clinical usefulness is yet to be demonstrated.
Selective Hemorrhoidal Dearterialization with High Mucopexy in the Surgical Treatment of Hemorrhoidal Disease
Authors: Rotta Carlos Mateus , Drago Stephanie , Sousa Afonso Henrique da Silva e , Martinez Carlos Augusto Real , Bernardino Marjorie Cristina da Cruz
Published: September 2021

The doppler-guided transanal hemorrhoidal dearterialization technique associated with mucopexy is a noninvasive surgical option used to treat hemorrhoidal disease (HD).

Objective To compare and analyze the results using a variation of the doppler-guided transanal hemorrhoidal dearterialization technique with the technique of selective hemorrhoidal dearterialization with high mucopexy in the treatment of HD.

Method A total of 292 patients who underwent surgical treatment for grade II, III and IV HD from March 2012 to December 2017 were studied. From this total, 110 (37.6%) patients underwent a conventional doppler-guided transanal hemorrhoidal dearterialization with mucopexy (CD), and 182 (62.3%) underwent selective hemorrhoidal dearterialization with high mucopexy (SHeLF). In the group of patients undergoing CD, 4 patients (3.64%) had grade II HD, 82 (74.55%) grade III, and 24 (21.82%) grade IV. In the group submitted to SHeLF, 18 (9.89%) patients had grade II HD, 86 (47.25%) had grade III, and 65 (35.71%) had grade IV. The same surgeon operated all patients under spinal anesthesia. In patients undergoing CD, six arterial branches have been dearterialized, while in patients undergoing SHeLF, the hemorrhoidary nipples submitted to a dearterialization were selected (from 1 to 5) by intraoperative evaluation followed by high rectal mucopexy. In the postoperative period, the following parameters were evaluated: pain, tenesmus, bleeding, and recurrence.

Moderate results to severe pain was a postoperative complaint reported by 13 (11.82%) patients undergoing CD, and by 19 (10.44%) undergoing SHeLF. Intense tenesmus was reported by 26 (23.64%) patients undergoing CD and by 7 (3.85%) undergoing SHeLF. Three patients (2.73%) undergoing CD and 1 (0.55%) undergoing SHeLF evolved with postoperative bleeding. One patient (0.55%) in the group undergoing CD required surgical review of hemostasis. Six patients (5.45%) who underwent CD and 8 (4.39%) who underwent SHeLF were reoperated due to disease recurrence.

Conclusion Comparing statistics, patients undergoing the SHeLF technique have less postoperative pain, tenesmus and postoperative bleeding when compared with CD.
Cultural macroevolution of musical instruments in South America
Authors: Aguirre-Fernández Gabriel , Barbieri Chiara , Graff Anna , Pérez de Arce José , Moreno Hyram , Sánchez-Villagra Marcelo R.
Published: September 2021

Musical instruments provide material evidence to study the diversity and technical innovation of music in space and time. We employed a cultural evolutionary perspective to analyse organological data and their relation to language groups and population history in South America, a unique and complex geographic area for human evolution. The ethnological and archaeological native musical instrument record, documented in three newly assembled continental databases, reveals exceptionally high diversity of wind instruments. We explored similarities in the collection of instruments for each population, considering geographic patterns and focusing on groupings associated with language families. A network analysis of panpipe organological features illustrates four regional/cultural clusters: two in the Tropical Forest and two in the Andes. Twenty-five percent of the instruments in the standard organological classification are present in the archaeological, but not in the ethnographic record, suggesting extinction events. Most recent extinctions can be traced back to European contact, causing a reduction in indigenous cultural diversity.