bluuebunny/crossref_metadata_2025 huggingface dataset:
CHILDREN AND THEIR PARENTS IN THE STRESS SITUATION OF THE COVID-19 PANDEMIC (RESULTS OF A COHORT STUDY IN THE VOLOGDA REGION)
Authors: Shmatova Yulia E. Shmatova , Razvarina Irina N.
Published: November 2022

Early in the COVID-19 pandemic, UNICEF warned that the mental well-being of children and adolescents could be severely affected. And their parents are also, according to scientists, a group of increased risk of adverse outcomes of the outbreak of a new coronavirus infection. This study presents selective results of the cohort monitoring “Studying the conditions for the formation of a healthy generation in the Vologda Oblast”, conducted by the Vologda Scientific Center of the Russian Academy of Sciences. The information base is the results of a survey of 364 mothers of children from three cohorts born in 2004, 2014 and 2020. (aged 1, 7 and 17). The problems and experiences faced by the families of children and adolescents during the pandemic are considered. Results: children, according to parents, most easily endured the situation of the spread of a new coronavirus infection. However, schoolchildren's mothers note in their children an increase in the level of fear for the health of loved ones, the emergence of problems with distance learning, a decrease in physical activity, excessive passion for gadgets, an increase in body weight, and a deterioration in physical and mental health. Parents of first-graders became the group at increased risk of developing adverse psychological outcomes of the pandemic. They were more likely than other parents to face economic problems, experienced anxiety and depressive symptoms, feelings of guilt towards children due to insufficient time and attention, their family members began to quarrel more often. Despite the severity of the condition, their behavior was dominated by constructive coping actions in a difficult life situation. The most protected in psycho-emotional and economic terms were the parents of children of the first year of life. Health, education and social policy professionals, governmental and non-governmental organizations have an important role to play in mitigating the psychosocial negative impacts of COVID-19 on children and adolescents and their parents.
SATISFACTION WITH THE EDUCATIONAL PROCESS AS A FACTOR OF PROTEST ATTITUDES OF STUDENT YOUTH
Authors: Shrayber Angelina N. , Artjukhina Valentina A.
Published: November 2022

Education is the main area of youth employment. It can be the main source of personal and group discontent. Analyzing the content of protest sentiments of students as their reaction to the ongoing events in the field of education, it is possible to predict and prevent protest behavior, as well as assess the quality of the educational environment. The empirical study included the collection and analysis of data obtained through questionnaires (n=608), in-depth interviews (n=12) and focus groups (n=10). The study identified the main indicators of satisfaction with the educational process of students, their attitude to distance learning, as well as problems that can provoke protest mood.
Por uma escuta da infância: inclusão escolar e as demandas pós-pandemia
Authors: Menezes Eliana , Schwertner Suzana Feldens , Hattge Morgana Domênica Hattge
Published: November 2022

Há aproximadamente dezessete meses vive-se os efeitos da pandemia de COVID-19 nas mais diferentes dimensões da vida social, dentre elas, a educacional. Nesse cenário, com o objetivo de discutir práticas de inclusão e exclusão produzidas no contexto do ensino remoto, propõe-se uma problematização sobre os efeitos dessas práticas nos processos de escolarização da infância que retorna à escola. Diante das limitações operadas pelo/no ensino remoto, debate-se a intensificação das práticas de responsabilização individual dos alunos com relação às dificuldades de aprendizagem por eles vivenciadas como consequência desse período de afastamento da escola. Questões que convidam a pensar sobre como a escola se reorganiza para possibilitar que tais dificuldades sejam minimizadas nortearam os tópicos que constituem o texto, cuja finalização foi construída a partir da defesa da potência da escola quando resiste ao imperativo da norma e atenta para a singularidade que constitui cada vida que a habita.
A escola em tempos de pandemia sob o olhar de professores em formação inicial: vivências e desafios
Authors: Lopes Rodrigo Oliveira , Mesquita Priscylla Jordania Pereira de , Lüdke Everton
Published: November 2022

Este artigo reflete sobre a escola em tempos de pandemia sob a óptica de professores em formação inicial, com base nas vivências destes sujeitos durante o Estágio Curricular Supervisionado em um Curso de Química Licenciatura. Adotando como problema de pesquisa:  quais as vivências e percepções de professores em formação inicial sobre a escola em tempos de Ensino Remoto Emergencial (ERE)? Foram analisados os relatórios de 11 estagiários por meio da Análise Textual Discursiva de Moraes e Galiazzi (2016), resultando em cinco categorias: a inserção do estagiário na escola, dificuldades dos estudantes sobre tecnologia, dificuldades de aprendizagem, questões emocionais docentes e desafios da prática docente. Foi possível reconhecer problemas de articulação entre as diferentes instâncias que regulam as atividades escolares e que os estudantes e suas famílias por vezes têm compreensões equivocadas sobre o ERE. Indicando a necessidade de reflexões sobre o atual momento envolvendo todos os agentes do ambiente escolar.
Formação contínua de professores e as (des)articulações com a escola de educação básica
Authors: Costa Elisangela André da Silva , Silva Maria do Socorro Lopes da , Costa Eisenhower Souza
Published: November 2022

O presente estudo toma como objetivo de investigação a formação contínua de professores. Parte da problematização do atual contexto, em que a docência e os processos formativos são cada vez mais atravessados por princípios neoliberais, que imprimem nas políticas educacionais a lógica da produtividade, performatividade e competitividade. Metodologicamente pautada na abordagem qualitativa, a investigação utilizou como estratégia de aproximação coma realidade uma entrevista narrativa, realizada junto a um professor que atua em turmas de ensino fundamental e médio no município de Horizonte-Ceará. Foi estabelecido como objetivo geral refletir sobre as articulações que se estabelecem entre a formação contínua e os desafios vividos pelos professores no exercício de sua profissão no contexto da educação básica.  Os resultados apontaram que mesmo atravessada pelas tensões e contradições presentes na sociedade contemporânea, a formação contínua pode se estabelecer como espaço de diálogo e de valorização da docência e da escola pública.
Educação e Tecnologia: perspectivas para diálogos em torno da educação para a emancipação
Authors: Almeida Antônio Charles Santiago de , Basniak Maria Ivete , Vidal Rafael Gemin
Published: November 2022

Este ensaio teórico, alicerçado em Adorno (2010), Bourdieu (2014) e Vieira Pinto (2005), admite que educação, política e tecnologia possuem uma relação quase simbiótica. A partir desses três autores, é apresentada uma discussão teórica sobre como as tecnologias, neste contexto, podem contribuir para a emancipação política de indivíduos que, quase sempre, não dispõem de uma herança de cultura. Bourdieu (2014) apresenta-nos os impedimentos de assegurar uma educação que seja justa para todos, pois, para ele, a escola é o lugar da desigualdade social. Por outro lado, Adorno (2010) discute que é preciso formar para a emancipação política, ou seja, para evitar o barbarismo cotidiano. A partir desse contexto de reprodução das estruturas dominantes, bem como de formar indivíduos participantes críticos, e de acordo com Vieira Pinto (2005), defendemos a  tese de que a apropriação da tecnologia pode configurar-se como instrumento de superação das desigualdades sociais e do encurtamento das distâncias entre os capitais de cultura.
IMPLEMENTATION OF ABILITY GROUPING IN CLASS MANAGEMENT IN MADRASAH DINIYAH RAUDHATUL MUBTADIIN KRAPYAK
Authors: Isnaini Rohmatun Lukluk , Nurmalita Aulia Haz
Published: November 2022

Placing students in classes that are not following their competencies has caused many problems, such us in the process of learning activities will be hampered. Ability grouping is one solution for grouping classes that are differentiated according to students' abilities. Thus, this research aims to determine how to implement ability grouping at Madrasa Diniyyah Raudhatul Mubtadiin Krapyak Yogyakarta. This research is descriptive qualitative research. The data collection techniques used were interviews, observations, and documentation studies. The informants consisted of 10 people: the head of the madrasa, three teachers, three guardians of students, and three students. The data obtained were analyzed through the transcript, coding, comparing and contrasting processes, and data interpretation. In achieving the validity of the data, triangulation of methods and sources is used. The results showed that 1) Ability grouping in Madrasah Diniyyah was carried out with three stages of tests, reading test, writing test and memorization test. 2) The positive impacts are high self-confidence, feeling more comfortable, a spirit of competition, and making it easier for teachers to deliver the material. Then, the negative impact is feeling inferior when in elementary class. 3) Supporting factors include support for the guardians of students, for students, and adequate infrastructure.
Parental Involvement in Children’s Initial Literacy Learning in Primary Schools in Mungwi District, Zambia
Authors: Kasakula Maureen
Published: November 2022

Abstract
This study sought to establish what primary schools were doing to ensure that there was parental involvement in children’s literacy learning. A qualitative design methodology was utilized, and data was collected through interviews, document analysis, and focus group discussions. The study found that parental involvement in children’s initial literacy learning in many schools was only achieved through the strategies put in place by some cooperating partners working with the schools such as Read to Succeed, a nongovernmental organization supported by the United States Agency for International Development (USAID). The strategies put in place by these partners enabled teachers and parents to work together so that parents were able to actively get involved in their children’s initial literacy learning. The study recommends that teacher education seriously consider including components on parental involvement in the college literacy syllabus to enhance teachers’ involvement of parents in children’s initial literacy learning in primary schools. The study further recommends that parental involvement in children’s literacy learning should be embedded in the school curriculum to enhance the commitment of teachers and school administrators.
 
Key Words: parental involvement, initial literacy, learning, primary schools, children
Introduction
Authors: Coronel-Molina Serafín M.
Published: November 2022

The International Journal of Literacy, Culture, and Language Education (IJLCLE) is an open-source, peer-reviewed international journal dedicated to publishing research in the field of literacy, culture, and language education from multi-, inter-, and transdisciplinary perspectives. Its mission is to promote the academic exchange of ideas and dissemination of research among scholars and researchers from diverse fields of study worldwide. Authors are invited to submit manuscripts describing scholarly research on a wide range of topics related to language, literacy, and culture in education. Theoretical and conceptual studies, empirical and applied research using qualitative and/or quantitative methodologies, critical papers, special issues, and book reviews are all invited. Contributions from a host of disciplines such as sociolinguistics, sociology of language, psycholinguistics, educational linguistics, applied linguistics, linguistic anthropology, raciolinguistics, literacy studies, cultural studies, language and gender studies, language and political economy, media and technology, language education, teacher education, educational policy, semiotics, pragmatics, language policy and planning, language revitalization, and linguistic landscapes are very welcome. The intended audience of IJLCLE is researchers, scholars, educators, and graduate students from around the world.
Refugees in Canada
Authors: Lynch-Kimery Melody
Published: November 2022

Humans are on the move. As refugees are forced and flow over borders due to war, violence, upheaval, and opportunity, the value of their language and professional experience is constantly questioned and often dismissed. Past and present research holds that learning a new home country's language is the critical component in refugee adjustment, success, and connection (Chiswick & Miller, 1995; Kosyakova et al., 2022). Much attention is focused on providing basic language training to refugees as a path to self-sufficiency, but there is little focus on language training for specific professions of expertise to help refugees retain and contribute to highly skilled professions. With Refugees in Canada: On the Loss of Social and Cultural Capital, Ricento fills a void by examining the need to recognize the capital that refugees bring and the pressing demand to refocus the language curriculum to better support and promote professional transitions.
Vowel Sounds in Hnaring Lutuv
Authors: Bohnert Amanda , Berkson Kelly , Par Sui Hnem
Published: November 2022

This squib presents a basic overview of the vowel sounds in Hnaring Lutuv.
A PHENOMENOLOGY OF FINANCIAL REPORT OF POLITICAL PARTIES IN BANTEN PROVINCE
Authors: Simanjuntak Dahnil Anzar
Published: November 2022

Political Parties propose their politician to the society for voted. They produce decision maker in legislative in particular. They had significant role in budgeting activities for public interest. Thus, transparency and accountability are absolutely needed, and the instrument of them, only couldprovide by accountancy. Political actor has significant role for made parties financial statement, based on those understanding, these research used phenomenology method, for answer how financial report made by political parties via their politicians, and what about with their perspectives about accountability and transparency. Transparency and accountability not as major goal for political parties. Political Parties in the it was clearly, the reason for made financial statement was not cause effort for creating public transparency and accountability in Banten Province, but more as reason for avoided from punishment, refer to the KPU Rule. This research reveal, political parties of financial statement made on as formality without substances for presenting accountability andtransparency, there was found a conclusion that political parties in Banten Province have a very low rates of accountability and transparency.
ANALYSIS OF RELATIONSHIP AMONG STAKEHOLDER PRESSURES, ENVIRONMENTAL MANAGEMENT ACCOUNTING USE, STRATEGY, AND INNOVATION: AN EMPIRICAL EVIDENCE FROM INDONESIA
Authors: Jayanti Arum Dwi , Mutmainah Siti
Published: November 2022

As an increased awareness of a global issue regarding the environmental impact of business activity; this study aims to examine the relationship among stakeholder pressures, environmental management accounting use, strategy, and innovation. This study is performed by conducting the survey to management accountants and environmental managers of companies in Indonesia. The convenience sampling technique was used and resulted in 34% response rate. The hypothesis testing was conducted by using Structural Equation Modeling (SEM) with SmartPLS 2.0 software. The results are: (1) the stakeholder pressures have a positive effect on EMA use, (2) the prospector strategy has no positive effect on EMA use, (3) EMA use has a positive effect on process innovation, but not with product innovation, (4) the prospector strategy has a positive effect on process innovation as well as on product innovation
DETERMINAN MANAJEMEN PAJAK PERUSAHAAN: UKURAN PERUSAHAAN, PENDANAAN UTANG, PROFITABILITAS, INTENSITAS ASET TETAP DAN MEKANISME TATA KELOLA
Authors: Pratiwi Umi
Published: November 2022

This study aims to examine financial (firm size, leverage, profitability, capital intensity) and non-financial factors (independent commissioners, audit committees, managerial ownership, institutional ownership as corporate governance mechanisms) on corporate tax management in manufacturing firms listed on the Indonesian Stock Exchange 2016-2017. The population of this research is 151 manufacturing firms. The sample measurement method is purposive sampling to obtain 36 sample firms with 72 observations according to the observation period. Data is analyzed with multiple regression analysis methods. The results of this research indicate that profitability, capital intensity, independent commissioners and audit committees influence the corporate tax management partially.  Meanwhile, firm size, leverage, managerial and institutional ownership have no influence on tax management. In general, corporate tax management can be indicated from the financial and non-financial factors.
HUBUNGAN INTELLECTUAL CAPITAL DENGAN KINERJA PERUSAHAAN
Authors: Saputra Achmad Arya Hudiyono
Published: November 2022

This study examines the relationship between intellectual capital and firm perfomance. This study is to prove that intellectual capital can be considered by management as a factor in improving frim performance. The population in this study are all those listed on the Indonesia Stock Exchange during the period 2014 to 2018 that has meet the criteria that have been determined. In this study, intellectual capital measured by using value added intellectual coefficient (VAIC™) method. The results suggest that the intellectual capital has a positive association with firm performance proxied with ROA and Tobin’s Q, implying that the intellectual capital help firm to increase it’s performance. This study supports the argument of resource based theory that if the intellectual capital can be managed properly by the firm, intellectual capital will increase competitive advantage for the firm and also can increase their performance.
KEPATUHAN PAJAK PELAKU UMKM DENGAN MODERASI KEADILAN PAJAK SEBUAH PENDEKATAN STRUKTURAL
Authors: Hardiningsih Pancawati , Srimindarti Ceacilia , Sutrisno Catur Ragil
Published: November 2022

The problem of low tax compliance is an ongoing problem in the taxation field. This conditionis very ironic with the growth rate of the number of businesses in Indonesia. This study aims toempirically examine the effect of understanding tax, service quality, and tax rates on taxcompliance. This study also examines tax justice as a moderating variable. The population inthis study is the UMKM taxpayer in the city of Semarang as many as 145 MSMEs in the 6 KPPPratama areas of the city of Semarang. The sample selection technique uses conveniencesampling method and obtained 110 MSMEs. Data were analyzed using the Smart Partial LeastSquare technique. The results showed that tax understanding, service quality and tax ratesaffect taxpayer compliance. While tax justice does not moderate the tax rates on taxcompliance. This research is able to explain that awareness of taxpayers starts to grow theimportance of paying taxes, therefore the government must improve public facilities andequitable development for the benefit of the community properly and correctly throughincreasing more intensive education at MSMEs.
CORPORATE GOVERNANCE, UKURAN PERUSAHAAN, LEVERAGE DAN REAL ERNINGS MANAGEMENT
Authors: Adi Yohana Epifani Kartika , Kusumaningtyas Metta
Published: November 2022

Investors always use various information to get maximum profit in investing activities. This study aims to examine the effect of corporate governance, firm size and leverage on real earnings management. Corporate governance is proxied by institutional ownership, the proportion of the independent board of commissioners, and the number of audit committee meetings. The sample of this research is 90 consumer goods industry companies listed on the Indonesia Stock Exchange, which were selected using a purposive sampling method during the 2014-2018 research period. The analysis technique used is multiple linear regression. The results of the study conclude that institutional ownership, the proportion of the independent board of commissioners and the number of audit committee meetings have no effect on real earnings management. However, firm size and leverage have a positive effect on real earnings management.
Devouring One´s Own Tail Autopoiesis in Perspective
Authors: Kolman Vojtěch , Murár Tomáš , Voldřichová Beránková Eva , Jirsa Jakub , Halík Tomáš , Lehečková Eva , Klír Tomáš , Petříček Miroslav , Procházka Martin , Slačálek Ondřej , Starý Jiří , Šebek Josef , Šlerka Josef , Vojvodík Josef
Published: November 2022

Inspired by Niklas Luhmann’s theories on social systems, this book examines the concept of autopoiesis, or self-creation, as it relates to society and culture. Approaching the concept from a variety of fields—philosophy, philology, aesthetics, linguistics, archaeology, and religious and media studies—the contributors present the products of humanity as self-referential, self-sustaining, and self-creating systems. Through four sections, the book addresses the philosophical concept of autopoiesis and its relations to creativity, destruction, and self-organization; autopoiesis in literature and art history; autopoiesis in religion; and autopoiesis in historiography, cognitive linguistics, and social media. Whether exploring Hegel’s theory of knowledge or the viral spread of conspiracy theories on the internet, the authors concentrate on the ouroboros-like nature of their subjects in the ways they feed off of themselves.
24/7 workflow for bloodstream infection diagnostics in microbiology laboratories: the first step to improve clinical management
Authors: Chirio David , Demonchy Elisa , Le Marechal Marion , Gaudart Alice , Lotte Romain , Carles Michel , Ruimy Raymond
Published: November 2022

Objectives

We aimed to evaluate the impact of an uninterrupted workflow regarding blood cultures on turnaround time and antibiotic prescription.

Methods

Monomicrobial episodes of bacteremia were retrospectively evaluated before and after a continuous 24/7 workflow was implemented in our clinical microbiology laboratory (pre- and post-intervention periods; PREIP and POSTIP). Primary outcome was the time from specimen collection to the first change in antibiotic therapy. Secondary outcomes included the time from specimen collection to effective antibiotic therapy and to antibiotic susceptibility testing results (or turnaround time), as well as hospital length of stay and all-cause mortality at 30 days.

Results

A total of 548 episodes of bacteremia were included in the final analysis. There was no difference in PREIP and POSTIP regarding patient characteristics and causative bacteria. In POSTIP, the mean time to the first change in antibiotic therapy was reduced by 10.4 h (p<0.001). The time to effective antibiotic therapy and the turnaround time were respectively reduced by 4.8 h (p<0.001) and 5.1 h (p=0.006) in POSTIP. There was no difference in mean hospital length of stay or mortality between the two groups.

Conclusions

Around the clock processing of blood cultures allows for a reduction in turnaround time, which in turn reduces the delay until effective antibiotic therapy prescription.
Preanalytical stability of SARS-CoV-2 anti-nucleocapsid antibodies
Authors: Niedrist Tobias , Kriegl Lisa , Zurl Christoph J. , Schmidt Felix , Perkmann-Nagele Nicole , Mucher Patrick , Repl Manuela , Flieder Ines , Radakovics Astrid , Sieghart Daniela , Radner Helga , Aletaha Daniel , Binder Christoph J. , Gülly Christian , Krause Robert , Herrmann Markus , Wagner Oswald F. , Perkmann Thomas , Haslacher Helmuth
Published: November 2022

Objectives

Anti-nucleocapsid (NC) antibodies are produced in response to SARS-CoV-2 infection. Therefore, they are well suited for the detection of a previous infection. Especially in the case of seroprevalence studies or during the evaluation of a novel in-vitro diagnostic test, samples have been stored at <−70 °C (short- and long-term) or 2–10 °C (short-term) before analysis. This study aimed to assess the impact of different storage conditions relevant to routine biobanking on anti-NC antibodies.

Methods

The preanalytical impact of short-term storage (84 [58–98] days) on <−70 °C and for 14 days at 2–10 °C was evaluated using samples from 111 donors of the MedUni Vienna Biobank. Long-term effects (443 [409–468] days) were assessed using 208 samples from Biobank Graz and 49 samples from Biobank Vienna. Anti-Nucleocapsid antibodies were measured employing electrochemiluminescence assays (Roche Anti-SARS-CoV-2).

Results

After short-term storage, the observed changes did not exceed the extent that could be explained by analytical variability. In contrast, results after long-term storage were approximately 20% higher and seemed to increase with storage duration. This effect was independent of the biobank from which the samples were obtained. Accordingly, the sensitivity increased from 92.6 to 95.3% (p=0.008). However, comparisons with data from Anti-Spike protein assays, where these deviations were not apparent, suggest that this deviation could also be explained by the analytical variability of the qualitative Anti-NC assay.

Conclusions

Results from anti-NC antibodies are stable during short-term storage at <−70 °C and 2–10 °C. After long-term storage, a slight increase in sensitivity could not be ruled out.
Hispanic-American dialectology in the 16th century. Penetration of Americanisms in Nicolas Monardes’ Historia Medicinal
Authors: Cáceres-Lorenzo María-Teresa
Published: November 2022

Historia medicinal (1565–1574) is an educational work that sought to promote knowledge of American phytotherapy for academic and economic purposes. This educational aim was accomplished after its publishing success in Spain and other European countries. Our objective is to examine the American words Nicolas Monardes chose and assess the degree of penetration of Native American loanwords and Americanised hispanicisms which have become fully incorporated into current American Spanish. The degree of penetration is measured through the variables with which they appear in the text (loanwords, number of appearances with or without explanation, used in medicine, medical term). 93 words were analysed using quantitative methodology and different degrees of penetration were detected. These terms included Native American loanwords, mediaeval medical hispanicisms, Spanish words created to describe American reality and neologisms that were widespread in the 16th century.
Postposed topic specification across the Sahara. An areal phenomenon
Authors: Lafkioui Mena B.
Published: November 2022

In the present study, I argue that post-posed topic specification (PTS) across the Sahara is an areal phenomenon and that in the case of Southern Tamazight (i.e., Tuareg & Zenaga) it is an innovation generated by pattern replication. On the other hand, the required matter for PTS formation in Southern Tamazight is generally provided by Tamazight itself by means of system-internal developments involving the following predominant grammaticalisation track, that is, [*modality markers > topic specifiers]. I also show that full convergence has taken place in these Southern Tamazight languages, which has affected their linguistic typology on the morphological, syntactic, and pragmatic level. Moreover, the study accounts for the significance of the functional parameter of contrast in the development of these topic specifiers and hence confirms the importance of system-based factors in language change.
Luxemburger Wirtshausnamen
Authors: Krier Fernande
Published: November 2022

This study deals with a rarely discussed lexicological and semantic issue, Luxemburgish names of inns. I was astonished by their large number and their diversification. In the Middle Ages, many people could not read, therefore an inn was indicated by a sign, for instance that of a raven that gave it its name. The name of the inn could give its situation in the village in order to help foreigners to find their way, for instance “At the market”. I examine historical relations, too, like “way of the Romans” and, on the other hand, names of animals, such as “At the raven”. Last not least I have discovered funny names like “kitchen of the devil” and original names, for instance ”Why not?” or “The peppercorn”. I don’t neither forget a very old house name, “Plutoshaff”, founded in the eighteenth century by Franz Plutot, a personality of the village.
Construction of mercury ion fluorescence system in water samples and art materials and fluorescence detection method for rhodamine B derivatives
Authors: Wang Zhankun , Hu Yanqiu , Zhou Xiaoxuan , Lv Yuguang
Published: November 2022

At present, the research on fluorescent molecular probe has become a hot topic in the field of environmental science, chemical materials, medicine, and other fields. Therefore, the detection of industrial mercury-containing wastewater (Hg2+) is of great significance. In this article, the fluorescent probe is used to detect mercury ions, and when compared with the traditional detection method, the fluorescent probe has the advantage of operation such as the effect of simplicity is evident. The experiments first synthesized rhodamine B derivatives and then the synthesized rhodamine B derivative fluorescent molecular probes were constructed and used to detect the mercury ions in water sample and oil paints. It was demonstrated that rhodamine B-derived probes have been constructed by UV and fluorescence spectroscopy. The different metal ions and rhodamine B-derived fluorescent molecular probes were compounded, resulting in the appearance of fluorescence peak centered at 583 nm only after the addition of metallic mercury ions with almost no response from other ions. The mercury ion rhodamine B derivative is more responsive to metallic mercury ions.
HOXA10 enhances cell proliferation and suppresses apoptosis in esophageal cancer via activating p38/ERK signaling pathway
Authors: Jiang Lifeng , Yang Qixian
Published: November 2022

Esophageal cancer (EC) is an extremely aggressive malignant tumor. Homeobox A10 (HOXA10) is highly expressed and plays an important role in a variety of tumors. However, the function of HOXA10 in EC remains unclear. In this study, HOXA10 was observed to highly express in EC tissues and cells. Interestingly, the CCK-8 assay, flow cytometry, and colony formation assay confirmed that overexpression of HOXA10 promoted proliferation and suppressed cell apoptosis in EC cells. More importantly, the western blot assay indicated that the phosphorylation levels of ERK and p38 were elevated in EC cells overexpressed HOXA10, indicating that overexpression of HOXA10 activated p38/ERK signaling pathway in EC cells. These findings concluded that HOXA10 aggravated EC progression via activating p38/ERK signaling pathway, providing a potential therapeutic target for EC.
Ideophones in Arusa Maasai: Syntax, morphology, and phonetics
Authors: Karani Michael , Andrason Alexander
Published: November 2022

The present article is dedicated to the syntax, morphology, and phonetics of ideophones in Arusa Maasai. After examining the compliance of 69 ideophonic lexemes with the typologically driven prototype of an ideophone, the authors conclude that Arusa ideophones may range from canonical to non-canonical even within a single language module. When syntax, morphology, and phonetics are considered jointly, holophrastic and asyntagmatic ideophones are more canonical than ideophones used as verbal modifiers and parts of complex predicates, which are, in turn, more canonical than predicative ideophones. The extent of canonicity is inversely correlated with the systematicity and integration of ideophones in sentence grammar and their diffusion into other lexical classes: predicative ideophones have been fully incorporated into the category of verbs; for ideophones employed as verbal modifiers, a comparable incorporation into the category of adverbs has not been completed; for all the other types, especially holophrastic and asyntagmatic, ideophones still maintain their categorical individuality. Overall, ideophones constitute an “old” category in Arusa, one that is well advanced on its grammaticalization cline.
In vitro evaluation of 2-pyrazoline derivatives as DPP-4 inhibitors
Authors: Temel Halide Edip , Altıntop Mehlika Dilek , Sever Belgin , Özdemir Ahmet , Akalın Çiftçi Gülşen
Published: November 2022

Objectives

In this study, the synthesis of three pyrazoline derivatives and the evaluation of their inhibitory effects on dipeptidyl peptidase (DPP-4) were aimed.

Methods

Pyrazoline-based compounds (1–3) were obtained via the reaction of 1-(2-furyl)-3-(1,3-benzodioxol-5-yl)-2-propen-1-one with 4-substituted phenylhydrazine hydrochloride. The DPP-4 inhibitory effects of compounds 1–3 were determined with a fluorometric assay using Gly-Pro-aminomethylcoumarin as the fluorogenic substrate. The cytotoxicity of compounds 1–3 on L929 mouse fibroblast (healthy) cell line was evaluated using MTT assay.

Results

1-(4-Methylsulfonylphenyl)-3-(2-furyl)-5-(1,3-benzodioxol-5-yl)-2-pyrazoline (2) exhibited the highest DPP-4 inhibitory activity (IC50=5.75 ± 0.35 µM). Moreover, compound 2 exerted no significant cytotoxicity against L929 cells (IC50=34.33 ± 7.09 µM).

Conclusions

Target compounds exhibited moderate DPP-4 inhibitory activity and compound 2 was identified as the most active compound.
Study structure and optical properties of Ag2Se, Ag2Se0.8Te0.2 and Ag2Se0.8S0.2 thin films
Authors:   Department of Physics, College of Education for Pure Science / Ibn Al-Haitham, University of Baghdad, Baghdad, Iraq, Ali Hiba M. , Khudayer I. H. ,   Department of Physics, College of Education for Pure Science / Ibn Al-Haitham, University of Baghdad, Baghdad, Iraq
Published: November 2022

Silver sulfide and the thin films Ag2Se0.8Te0.2 and Ag2Se0.8S0.2 created by the thermal evaporation process on glass with a thickness of 350 nm were examined for their structural and optical properties. These films were made at a temperature of 300 K. According to the X-ray diffraction investigation, the films are polycrystalline and have an initial orthorhombic phase. Using X-ray diffraction research, the crystallization orientations of Ag2Se and Ag2Se0.8Te0.2 & Ag2Se0.8S0.2 (23.304, 49.91) were discovered (XRD). As (Ag2Se and Ag2Se0.8Te0.2 & Ag2Se0.8S0.2) absorption coefficient fell from (470-774) nm, the optical band gap increased (2.15 & 2 & 2.25eV). For instance, the characteristics of thin films made of Ag2Se0.8Te0.2 and Ag2Se0.8S0.2 and silver sulfide have been studied.
Time required for commitment to T cell proliferation depends on TCR affinity and cytokine response
Authors: Wu Liang‐zhe , Balyan Renu , Brzostek Joanna , Zhao Xiang , Gascoigne Nicholas R J
Published: November 2022

T cell activation and effector functions are determined by the affinity of the interaction between T cell receptor (TCR) and its antigenic peptide MHC (pMHC) ligand. A better understanding of the quantitative aspects of TCR‐pMHC affinity‐dependent T cell activation is critical for the development of new immunotherapeutic strategies. However, the role of TCR‐pMHC affinity in regulating the kinetics of CD8+ T cell commitment to proliferation and differentiation is unknown. Here, we show that the stronger the TCR‐pMHC affinity, the shorter the time of T cell‐APC co‐culture required to commit CD8+ T cells to proliferation. The time threshold for T cell cytokine production is much lower than that for cell proliferation. There is a strong correlation between affinity‐dependent differences in AKT phosphorylation and T cell proliferation. The cytokine IL‐15 increases the poor proliferation of T cells stimulated with low affinity pMHC, suggesting that pro‐inflammatory cytokines can override the affinity‐dependent features of T cell proliferation.
Doctors, teach your adrenal insufficiency patients well: provide them with a European Emergency Card!
Authors: Beun Johan G , Burman Pia , Kämpe Olle , Husebye Eystein S , Hahner Stephanie , Kristensen Jette , Noordzij Alida , Dahlqvist Per
Published: November 2022

Adrenal insufficiency is a life-threatening condition requiring chronic glucocorticoid replacement therapy, as well as stress adaptation to prevent adrenal crises. To increase patients’ self-sustainability, education on how to tackle an adrenal crisis is crucial. All patients should carry the European Emergency Card.
Надтверді матеріали для оборонної промисловості та повоєнного розвитку України
Authors: Бочечка Олександр Олександрович
Published: November 2022

У доповіді наведено найбільш важливі й актуальні результати фундаментальних і прикладних досліджень, проведених в Інституті надтвердих матеріалів ім. В.М. Бакуля НАН України, завдяки яким в Україні створено науково-технічну базу для розроблення сучасних технологій та обладнання з надтвердих матеріалів, що дає можливість значно підвищити якість і продуктивність виготовлення інструментів та деталей, зокрема для військової техніки.
Національне відродження України у повоєнний період
Authors: Зеленько Галина Іванівна
Published: November 2022

У доповіді зазначено, що з початком повномасштабного російського воєнного вторгнення в Україні відбулося істотне прискорення процесів націєтворення. Те, на що раніше потрібні були десятиліття, зараз змінюється за місяці чи навіть тижні. Підкреслено, що Українська держава виявилася значно міцнішою, ніж здавалося, а національна стійкість, як показала війна, ґрунтується насамперед на здатності суспільства до самоорганізації. Саме суспільна самоорганізація і має стати основою повоєнного відновлення України.
Про роботу установ Північно-Східного наукового центру НАН України і МОН України, які розташовані у районах проведення активних бойових дій
Authors: Семиноженко Володимир Петрович
Published: November 2022

Доповідь і виступи в її обговоренні присвячено підсумкам робочого візиту президента НАН України академіка НАН України А.Г. Загороднього та віцепрезидента НАН України, в.о. головного вченого секретаря НАН України академіка НАН України В.Л. Богданова, які 18—19 серпня 2022 р. відвідали установи Північно-Східного наукового центру НАН України і МОН України у Харкові та ознайомилися з умовами їхньої роботи під час активних воєнних дій на території міста та області.
Інноваційний підхід до національної стійкості України: стратегія випередження загроз
Authors: Андрущенко Віктор Петрович
Published: November 2022

Національна доповідь, підготовлена колективом фахівців Секції суспільних і гуманітарних наук НАН України, є спробою в сучасних геополітичних умовах обґрунтувати концепцію національної стійкості (резильєнтності) як стійкості цивілізаційної суб’єктності країни, визначити її стратегію забезпечення збалансованості розвитку та успішної протидії і випередження зовнішніх та внутрішніх загроз, у тому числі гібридних. Досліджено питання взаємодії національної стійкості й національної безпеки держави, поставлено проблему інституційного забезпечення стратегії національної стійкості.
КОМП’ЮТЕРНЕ МОДЕЛЮВАННЯ ПОВЕДІНКИ КУСКОВО-ОДНОРІДНИХ ПЛАСТИН З ДВОМА КРУГОВИМИ ТА ЕЛІПТИЧНИМИ ОТВОРАМИ
Authors: Гарт Е.Л. , Поцелуйко Є.О.
Published: November 2022

Проведено комп’ютерне моделювання поведінки тонких пружних кусково-однорідних прямокутних пластин з двома центрально розташованими круговими та еліптичними отворами за дії одновісного розтягувального навантаження. Із застосуванням методу скінченних елементів досліджено вплив механічних і геометричних параметрів центральної вставки з іншого матеріалу, конфігурації та розташування отворів на концентрацію напружень навколо них. Здійснено порівняльний аналіз отриманих результатів щодо зниження концентрації напружень з результатами для відповідних однорідних пластин.
МАТЕМАТИЧНЕ МОДЕЛЮВАННЯ ВПЛИВУ ТЕМПЕРАТУРНОГО РЕЖИМУ НА ЕФЕКТИВНІСТЬ СОНЯЧНОЇ ПАНЕЛІ
Authors: Захаров Д.В. , Книш Л.І.
Published: November 2022

Побудовано стаціонарну 2D математичну модель, що описує перенос енергії в монокристалічній кремнієвій сонячній панелі. Апроксимовані експериментальні дані температурної залежності коефіцієнта корисної дії сонячної панелі були введені в рівняння як джерельний член. Вплив умов навколишнього середовища враховувався в нелінійних граничних умовах моделі. Розроблено ітераційний числовий алгоритм, на основі якого отримано двовимірне поле температур в кремнієвій сонячній панелі. Проведено порівняння середньої ефективності сонячної панелі для двох випадків: з урахуванням залежності коефіцієнту корисної дії від температури та при постійному значенні коефіцієнта корисної дії. Отримані дані можуть використовуватись при проєктуванні  сонячних панелей та оптимізації їх роботи.
ПЛОСКА ДЕФОРМАЦІЯ П’ЄЗОЕЛЕКТРИЧНОГО БІМАТЕРІАЛУ З ДВОМА ЕЛЕКТРОПРОНИКНИМИ ТРІЩИНАМИ НА МЕЖІ ПОДІЛУ РІЗНИХ КОМПОНЕНТ
Authors: Костенко М.В. , Сіліч-Балгабаєва В.Б. , Шевельова А.Є. , Лобода В.В.
Published: November 2022

Вивчається взаємодія двох електропроникних тріщин довільної довжини на межі поділу п’єзоелектричних матеріалів. Проблема зведена до задачі лінійного спряження. Знайдено її точний аналітичний розв’язок. Отримані представлення механічних та електричних компонент на берегах тріщин та на частинах інтерфейсу поза тріщинами. Знайдені коефіцієнти інтенсивності напружень та швидкості звільнення енергії для всіх вершин тріщин. Досліджена залежність вказаних факторів від довжини тріщин та відстані між ними
ПРЯМОКУТНА ПЛАСТИНКА З БОКОВИМИ ВИТОЧКАМИ В УМОВАХ ПОВЗУЧОСТІ
Authors: Панин К.В. , Чіквана С.
Published: November 2022

Розглядається усталена повзучість прямокутної пластинки з боковими виточками. Запропоновано числовий алгоритм розв’язання цієї граничної задачі. Він базується на застосуванні методу скінченних елементів і варіанту теорії старіння (Работнова). З урахуванням подібності ізохронних кривих повзучості матеріалу пластинки гранична задача теорії повзучості зведена до задачі в рамках деформаційної теорії пластичності для певного моменту часу. Лінеаризація рівнянь деформаційної теорії пластичності досягається за допомогою методу змінних параметрів пружності. На кожному кроці методу змінних параметрів пружності застосовується метод скінченних елементів. Як базовий для даного методу обраний ізопараметричний чотирикутний скінченний елемент. Отримані картини напружено-деформованого стану пластинки для різних моментів часу.
ЛОКАЛІЗОВАНІ ТА НЕЛОКАЛЬНІ ФОРМИ КОЛИВАНЬ ДВОХ ПОВ’ЯЗАНИХ МАЯТНИКІВ
Authors: Сурганова Ю.Е. , Міхлін Ю. В. , Кирилова Н.О.
Published: November 2022

Розглянуто форми коливань системи, що складається з двох маятників, пов'язаних пружною пружиною, причому маси цих маятників істотно розрізняються. Локалізовані і нелокальні (пов'язані) форми коливань отримано за допомогою методу малого параметра. Числове моделювання, що включає побудову фазових портретів і траєкторій в конфігураційному просторі, дозволяє оцінити стійкість отриманих форм коливань.
ВЗАЄМОДІЯ МІЖФАЗНИХ ТРІЩИН З РІЗНИМИ ЕЛЕКТРИЧНИМИ ТА МАГНІТНИМИ УМОВАМИ НА ЇХ БЕРЕГАХ У П’ЄЗОЕЛЕКТРОМАГНІТНОМУ КОМПОЗИТІ
Authors: Шевельова Н.В. , Ходанен Т.В.
Published: November 2022

Розглядається плоска деформація двох спаяних п’єзоелектромагнітних півпросторів з двома тріщинами на межі поділу матеріалів. Вважається, що одна з тріщин є електромагнітопровідною, а інша електромагнітопроникною. На нескінченності прикладені рівномірно розподілене антиплоске зсувне механічне навантаження та електричне і магнітне поля. Проблема зведена до задач лінійного спряження для кусково-аналітичних функцій, для яких отримано точні аналітичні розв’язки. На їх основі одержано аналітичні вирази для напружень, електричного та магнітного полів на межі поділу матеріалів поза тріщинами, а також розкриття тріщин і стрибки електричного і магнітного зміщень при переході через тріщини. Для різних довжин тріщин, відстаней між ними та різних значень механічного, електричного та магнітного навантажень наведено чисельну ілюстрацію одержаних результатів.Отримані результати представлено в графічній формі.
Desafíos y oportunidades en una metrópolis contraurbanizada. Movilidad regional en tiempos de COVID-19
Authors: Boccolini Sara María
Published: November 2022

En un territorio metropolitano profundamente desigual, las estrategias de movilidad cotidiana permiten desarrollar redes de asistencia y apoyo interpersonales, y acceder a recursos/servicios estratégicos para asegurar una adecuada calidad de vida. Según esta premisa, se exploró el aumento en la vulnerabilidad socioeconómica/sanitaria y los conflictos que emergieron de las restricciones a la movilidad para la contención y prevención de contagios de COVID-19 en la Región Metropolitana de Córdoba (Argentina) durante 2020.
Se analizaron estadísticas, estudios técnicos y testimonios en la prensa para caracterizar la estructura socio-funcional regional, sus patrones de movilidad cotidiana y cómo estos se transformaron debido a esas restricciones. Finalmente, se caracterizó su impacto en la calidad de vida de las personas.
Los resultados muestran que las contradicciones entre estas restricciones y los patrones de movilidad cotidiana (estructurados por la contraurbanización y la movilidad cotidiana pendular que caracterizan la región) agravan situaciones de vulnerabilidad existentes y crean nuevas situaciones de riesgo que afectan a toda la población, pero sobre todo a los grupos más empobrecidos, a jóvenes y a mujeres. Esto afirma la importancia de incorporar la movilidad cotidiana regional en el desarrollo de políticas sanitarias efectivas, sostenibles e inclusivas.
COVID-19 y digitalización en contextos de pobreza urbana
Authors: Verón Eduardo Francisco , Grinberg Silvia Mariela
Published: November 2022

La pandemia del COVID-19 produjo importantes cambios en los modos de vida de la población, entre ellos las formas en que se desarrolla la reproducción diaria de las familias. En este artículo describimos los cambios que produjo la pandemia en el desarrollo de estrategias de subsistencia de la población que habita en contextos de extrema pobreza urbana en la Región Metropolitana de Buenos Aires. A través de trabajo en campo de largo plazo y de la obtención de datos de modo digital, nos ocupamos de indagar cómo en los barrios más empobrecidos se desarrollaron nuevos circuitos para el desarrollo de las actividades de subsistencia en el mundo digital, y cómo la vida urbana en estos espacios se mudó al espacio de la virtualidad. En el presente artículo, a través de Verónica, vecina de uno de esos barrios, nos adentramos en las dinámicas de la vida barrial y en su reproducción diaria, asociada a la recolección y reciclaje de residuos, el consumo y la venta en ferias populares. Después nos ocupamos del desarrollo digital de estos procesos en 2020, a medida que la cuarentena desarticulaba las dinámicas presenciales.
PENDAMPINGAN PEMBUATAN KRAN LESS CONTACT UNTUK MENGURANGI PENYEBARAN COVID-19 DI MASJID FATHUL JANNAH
Authors: Supiyati Supiyati , Yuliza Elfi , Ekawita Riska
Published: November 2022

Fasilitas umum tempat wudhu dan mencuci tangan di Masjid Fathul Jannah masih menggunakan kran biasa, padahal banyak jamaah menggunakan fasilitas mencuci tangan ini, yang dimungkinkan akan menjadi tempat penularan covid-19. Tujuan dari kegiatan ini adalah  memberikan edukasi cara penggunaan fasilitas cuci tangan/ wudhu yang tepat pada jamaah untuk mencegah penularan covid-19, memberikan pengetahuan dan keterampilan serta pendampingan pada pengurus masjid Fathul Jannah mengenai teknologi sederhana cara merangkai dan membuat program sistem kran less contact, beserta instalasinya. Metode dalam kegiatan pengabdian pada masyarakat ini adalah pelatihan dan pendampingan. Hasil kegiatan menunjukan bahwa kegiatan pengabdian pada masyarakat dapat dilaksanakan dengan baik dan lancar. Berdasarka free test dan post test yang telah dilakukan terjadi peningkatan pengetahuan para peserta 95%.  Peserta dengan didampingi tim pengabdi sudah berhasil merangkai dan memogram dua set kran less contact . Peserta juga telah berhasil memasang instalasi  kran less contact di masjid Fathul Jannah dan sudah dapat digunakan oleh jamaah masjid untuk cuci tangan dan wudhu tanpa menyentuh kran, sehingga usaha untuk mengurangi penyebaran covid-19 telah berhasil dilaksanakan.