bluuebunny/crossref_metadata_2025 huggingface dataset:
Kegiatan sebagai Pembicara dalam Seminar Merajut Nusantara “Kemampuan Digital yang Dicari Saat ini”
Authors: TIUAJ Yanto
Published: September 2024

This community service activity aimed to provide insight and knowledge regarding digital skills needed in the future for the participants. There were three speakers who presented various topics related to digital skills in demand today. In the digital era, it requires people who have adequate relevant digital skills. Based on presentation, 7 digital skills in demand today are social media skills, the ability to optimize SEM (Search Engine Marketing), data analytics, content marketing, social selling, mobile marketing skills and the ability to create or modify video content. In this digital era, creativity, innovation and adaptability are needed so that individuals are able to compete and to be successful.
Prebiotic Activity of Plants from Cucurbitaceae Family and In Vitro Fermentation by Gut Microbiota
Authors: Ab Azid Saffanah Mohd , Wichienchot Santad , Wan Ishak Wan Rosli , Safuan Sabreena
Published: September 2024

This study aims to examine the effect of Freeze-Dried Pumpkin Powder (FDPP), Freeze-Dried Winter Melon Powder (FDWMP), Freeze-Dried Rock Melon Powder (FDRMP), inulin, and D glucose on prebiotic activity score by in vitro fermentation. We also elucidate the changes in bacterial populations through batch culture fermentation using fecal samples from 5 healthy volunteers and In vitro fecal fermentation using batch culture and analyses of Short-Chain Fatty Acids (SCFAs). The growth of Bifidobacterium has significantly increased from 0 (8.90±0.05 log10 cells/mL) and 72h (8.83±0.14 log10 cells/mL) for D glucose and FDWMP (8.75±0.07 log10 cells/mL (0h) and 8.87±0.12 log10 cells/mL (72h)). However, the increase in population was not significant for inulin (9.15±0.06 log10 cells/mL), FDPP (9.04±0.12 log10 cells/mL), and FDRMP (8.67±0.08 log10 cells/mL). The number of Lactobacili significantly increased at 6h for FDPP (9.11±0.07 log10 cells/mL) and 24h for FDWMP (8.88±0.07 log10 cells/mL) and FDRMP (8.80±0.09 log10 cells/mL). Acetic acid was detected in all samples, and the concentration increased in all vessels at any given time except for the FDWMP fermentation, which decreased after 0h and increased after 6h. Overall, FDWMP has increased the probiotic growth of L. plantarum TISTR 1465 and exhibit the highest prebiotic index. As a result, it is suggested that the FDWMP be potentially used as a healthy raw material in developing varieties of functional prebiotic food products.
A rare presentation of labial porokeratosis: An innovative approach yielding exceptional esthetic results
Authors: Bhingradia Yogesh M. , Farista Arshi , Solanki Vikas Ganesh , Mehra Mriganka
Published: September 2024

Porokeratosis (PK) is a rare genodermatosis characterized by abnormal keratinization, resulting in crateriform lesions with central atrophy and distinct ridge-like borders. We present an unusual case of isolated labial PK in a 50-year-old female without oral mucosal involvement. The patient underwent successful treatment with CO2 laser ablation, resulting in complete resolution without recurrence during a 9-month follow-up period.
Optimizing surgical technique in microvascular decompression for hemifacial spasm – Results from a surgical series with contemporary use of neuronavigation and intraoperative neuromonitoring
Authors: Battistelli Marco , Izzo Alessandro , D’Ercole Manuela , D’Alessandris Quintino Giorgio , Di Domenico Michele , Ioannoni Eleonora , Gelormini Camilla , Martinelli Renata , Valeri Federico , Grilli Fulvio , Montano Nicola
Published: September 2024

Background:

Microvascular decompression (MVD) through a retrosigmoid approach is considered the treatment of choice in cases of hemifacial spasm (HFS) due to neurovascular conflict (NVC). Despite the widespread of neuronavigation and intraoperative neuromonitoring (IONM) techniques in neurosurgery, their contemporary application in MVD for HFS has been only anecdotally reported.

Methods:

Here, we report the results of MVD performed with a combination of neuronavigation and IONM, including lateral spread response (LSR) in 20 HFS patients. HFS clinical outcome and different surgical-related factors, such as craniotomy size, surgical duration, mastoid air cell (MAC) opening, postoperative cerebral spinal fluid (CSF) leakage, sinus injury, and other complications occurrence, and the length of hospitalization (LOS) were studied.

Results:

Postoperatively, residual spasm persisted only in two patients, but at the latest follow-up (FU) (mean: 12.5 ± 8.98 months), all patients had resolution of symptoms. The mean surgical duration was 103.35 ± 19.36 min, and the mean LOS was 2.21 ± 1.12 days. Craniotomy resulted in 4.21 ± 1.21 cm2in size. Opening of MAC happened in two cases, whereas no cases of CSF leak were reported as well as no other complications postoperatively and during FU.

Conclusion:

MVD for HFS is an elective procedure, and for this reason, surgery should integrate all technologies to ensure safety and efficacy. The disappearance of LSR is a crucial factor for identifying the vessel responsible for NVC and for achieving long-term resolution of HFS symptoms. Simultaneously, the benefits of using neuronavigation, including the ability to customize the craniotomy, contribute to reduce the possibility of complications.
THE GENERALIZATION OF THE LOGISTICAL EQUATIONS TO ACCOUNT OF THE INITIAL VELOCITY
Authors: Кудин В.Н.
Published: September 2024

Анализируются принципиальные особенности решений в связи с изменениями параметров логистического уравнения с нулевым слагаемым. Отмечается расширение диапазона решений, которые позволяют подробнее исследовать устойчивость развития численности населения регионов европейской части Российской Федерации.

The principle particularities of the solutions are analysed in connection with change parameter logistic equations with zero composed. It is noted expansion of the range of the equations, which allow in detail to research stability of the development to number of the population European partial region to Russian Federation.
POSSIBLE PARAMETERS OF NEUTRON SOURCE BASED ON TOKAMAK WITH TRITIUM OPERATION IN A DEUTERIUM PLASMA
Authors: ЧИРКОВ А.Ю. , ФЕДЮНИН Д.Е.
Published: September 2024

Рассматривается возможность использования D–D-реакции в плазме токамака для генерации нейтронов. Оценивается эффективность соответствующей гибридной системы «синтез-деление», использующей тритий, производимый в D–D-реакции в плазме. При этом отпадает необходимость производить тритий в бланкете и, возможно, увеличивается производство делящегося ядерного топлива на один нейтрон. Показано, что в токамаке с аспектным соотношением А = 2 коэффициент усиления в дейтериевой плазме может достигать Q ~ 0,3. Рассматриваются два варианта топливного цикла гибридной системы. В первом случае весь нарабатываемый тритий сжигается в катализированном D–D-цикле в токамаке с A = 2. Во втором варианте сжигается только 50 % трития, а 50 % – используются в токамаке относительно небольших размеров с А = 3, работающем на D–T-топливе.

The possibility of using the D–D reaction in a tokamak plasma to generate neutrons is considered. The efficiency is evaluated for the corresponding hybrid fusion–fission system using tritium produced in the D–D reaction in plasma. In such a system, there is no need to produce tritium in a blanket and, possibly, the production of fissile nuclear fuel per neutron increases. It is shown that in a tokamak with an aspect ratio A = 2, the gain in a deuterium plasma can reach Q ~ 0.3. Two versions of the hybrid system fuel cycle are considered. In the fi rst case, all the accumulated tritium is burned in the catalyzed D–D cycle in the tokamak with A = 2. In the second version, only 50% of tritium is burned, and 50% is used in the relatively small tokakamak with D–T fuel.
THE EMERGENCE OF THE THEORY OF THE GAMMA-FUNCTION IN THE RESEARCH OF L. EULER
Authors: Игнатушина И.В.
Published: September 2024

Настоящая статья посвящена творчеству Леонарда Эйлера по теории специальных функций. Помимо его опубликованных сочинений, в которых затронуты вопросы теории Г-функции, к исследованию были привлечены переписка Эйлера с учеными и неопубликованные материалы из его записных книжек, касающиеся этой теории. Это дает возможность проследить ход мысли великого ученого при разработке математической теории и выяснить, когда и при решении каких задач Эйлер пришел к понятию Г-функции.

The article deals with the reform taking place in the national high school of XX–beginning of XXI centuries. By analyzing changes in the national high school, the author identifi es in its history since 1917 of nine periods and describes the features of each of them.
HISTORY OF THE GREAT FAMILY: GENEALOGY OF THE NOBELS DYNASTY
Authors: Тютюнник В.М.
Published: September 2024

Чрезвычайно противоречивая и загадочная личность Альфреда Бернхарда Нобеля, покрытая секретами деятельность Нобелевских комитетов и награждающих организаций по присуждению Нобелевских премий, резко меняющиеся по своей сути официальные и неофициальные оценки А. Нобеля и Нобелевских премий, в том числе и в печати (что значительно повышает интерес к ним), рассеянность информации по различным источникам, особенно в интернете, а главное – масса ошибок и путаницы с пятью Нобелевскими премиями и одной мемориальной, четырьмя братьями Нобелями, их отцом и другими известными родственниками, датами – вот та серия причин, которые побудили автора восстановить генеалогию великого семейства и снабдить её жизнеописаниями каждого Нобеля и наукометрическими данными. Детально описана генеалогия И. Нобеля, Р. Нобеля, Л. Нобеля, А.Б. Нобеля, К. Нобеля и их семей.

Extremely controversial and enigmatic personality of Alfred Bernhard Nobel, coated secrets activities of Nobel Committees and Awarding organizations for Nobel Prize Awards, dramatically changing fundamentally formal and informal evaluation of A. Nobel and Nobel prizes, including in print (which signifi cantly increases the interest in them), the diffusion of information on the various sources, especially online, and most importantly are the mass of errors and confusion with fi ve Nobel prizes and one Memorial prize, with four Nobel brothers, their father and other relatives, dates there are the series of reasons which prompted the author to recover the great family genealogy and implement its biographies of each Nobels and scientometrics data. Genealogies of I. Nobel, R. Nobel, L. Nobel, A.B. Nobel, K. Nobel and their families are described in detail.
A.V. Ossovsky and the "new music"
Authors: Смирнов В.В.
Published: September 2024

В статье раскрывается малоизвестный аспект деятельности выдающегося отечественного исследователя А.В. Оссовского – активная поддержка современного музыкального процесса в дореволюционные годы. В статьях 1894–1912 гг. критик идет навстречу новой западноевропейской музыке – творениям Дебюсси, Равеля, Р. Штрауса, Малера – и в то же время вписывает русскую музыку в общеевропейский контекст. Подобный интегрированный подход свидетельствует о подлинном историзме мышления Оссовского – качестве, сформировавшемся уже в начале его многолетнего творческого пути.

This article is devoted to little known aspect of activity of outstanding Russian researcher A.V. Ossovsky – to an active support of the modern musical process in the pre-Revolution years. In his articles from 1894 to 1912 the critic goes towards the new music of West Europe – to compositions by Debussy, Ravel, R. Strauss, Mahler, meanwhile placing the Russian music into the European context. Such integrated approach witnesses the real historicism of Ossovsky’s way of thinking, which trait being formed already in the beginning of his perennial creative path.
Aesthetic paradigms of integral serialism
Authors: Окунева Е.Г.
Published: September 2024

Сериализм – важнейший феномен, обусловивший переворот в музыкальном сознании середины ХХ века. В этот период теоретические размышления композиторов были неотделимы от их художественной практики. На основе теоретических работ и музыкальных сочинений Булеза, Штокхаузена, Кшенека, Гуйвартса, Адорно, Ноно и др. в статье выстроена эстетическая концепция сериализма, которая способствовала изменению музыкальной картины мира. Среди ключевых принципов сериализма автор выделяет: девальвацию антропоцентризма, отказ от автономного произведения искусства, материальное мышление, эстетику tabula rasa, установку на эксперимент, новый взгляд на творческий процесс, онтологическую программность, антисубъективизм, научно-ориентированный взгляд на мир, теоретизацию композиторской практики. Для музыки второй половины ХХ века концепция сериализма приобрела эпохальное значение. Сериальное мышление оказало существенное влияние на дальнейшие поиски композиторов в области музыкального языка.

Integral serialism is the most important phenomenon that caused a revolution in the musical consciousness in the middle of the XX century. During this period, the theoretical refl ections of the composers were inseparable from their art practice. Based on theoretical writings and musical compositions of Boulez, Stockhausen, Krenek, Goeyvaerts, Adorno, Nono, and others in the article builds up the aesthetic concept of integral serialism, which promoted a change of a musical picture of the world. As key principles, the author considers the devaluation of anthropocentrism, the refusal of an autonomous work of art, the material thinking, the aesthetics of tabula rasa, orientation to experiment, a new view of creative process, ontology program, antisubjectivity, scientific view of the world, the theorization of composing practice. For music of the second half of the twentieth century, the concept of integral serialism acquired epoch-making signifi cance. Serial thinking has had a signifi cant impact on further researches of composers in the field of music language.
Plot 510A “Cinderella” in the Russian Tradition: Folklore Tale and Literary Influence
Authors: Добровольская В.Е.
Published: September 2024

В статье рассматриваются особенности реализации сюжетного типа СУС 510А «Золушка» в русской сказочной традиции. Анализ имеющихся в нашем распоряжении фольклорных текстов показал, что мы можем выделить в корпусе текстов три группы. К первой относятся сказки, соответствующие в большей или меньшей степени сюжетной схеме 510 и не испытывающие очевидного литературного влияния. Вторую группу составляют произведения, в той или иной степени испытавшие влияние сказки либо Ш. Перро, либо братьев Гримм. Наконец, третья группа формируется из текстов, представляющих собой контаминацию типов СУС 511 и 510А, а также 409. В ряде случаев мы можем говорить и о влиянии на данные тексты литературы и иноэтничных традиций. Таким образом, русская сказочная традиция применительно к сюжетному типу СУС 510А практически не испытывает влияния литературы, но сюжет открыт для контаминаций с другими сюжетными типами и в то же время может существовать самостоятельно.

This paper examines how plot type 510A, “Cinderella”, functions in the Russian fairy tale tradition. An analysis of the texts at our disposal shows that we can distinguish three groups in the corpus of texts. The first includes fairy tales that correspond to a greater or lesser extent to the plot scheme 510 and do not have an obvious literary influence. The second group consists of texts representing fairy tales that have been influenced to some degree by the fairy tales of Charles Perrault or the Brothers Grimm. Finally, the third group consists of texts representing contamination of types SUS 511 and 510A, as well as 409. In some cases, we can also talk about the influence of written texts and non-Russian ethnic traditions on these texts. Analysis of the texts shows that the Russian fairy tale tradition in relation to the SUS 510A plot type is practically free of literary influence, although it is open to contamination by other plot types and at the same time can also exist independently.
Between Lubki and Folklore: On the Textology of Comic “Wedding Decrees”
Authors: Крашенинникова Ю.А.
Published: September 2024

Настоящая работа посвящена свадебным указам — текстам свадебного обряда, зафиксированным в двух граничащих друг с другом локальных традициях России — Ростовском уезде Ярославской губернии и Переславль-Залесском уезде Владимирской губернии, преимущественно в последней трети XIX — первой трети XX в. Проанализированы тематика, отдельные «типовые элементы» указов, выявлены формулы и устойчивые выражения, заимствованные указами из шуточных «Росписей о приданом», описаны некоторые механизмы усвоения указами лубочного и фольклорного репертуара. Набор тем шуточных «Росписей о приданом» объясняется ориентированностью этих текстов на невесту. Создатели свадебных указов, сохранив ориентацию на невесту (пародийная характеристика приданого и хозяйственных навыков девушки), обратили более пристальное внимание на жениха. Сопоставительный анализ демонстрирует мозаичность и формульность текстовой фактуры свадебных указов, художественно-стилистическое сходство с произведениями демократической сатиры, лубка, фольклора. Взяв за основу «Роспись о приданом» (отдельные темы и принципы построения текста, на что справедливо указала Е. Э. Бломквист), создатели указов, ориентируясь на круг актуальных для обрядовой ситуации тем, привлекали свадебные приговоры, корильные песни, рождественские славления, малые жанры, небывальщины; весьма много текстовых схождений указов и произведений народного театра (сценки ряженых, сатирические драмы, пьесы кукольного театра).

The present work is devoted to wedding decrees  — comic texts recited during wedding rituals  — from two neighboring local Russian traditions: from the Rostov district in Yaroslavl Province and from the Pereslavl-Zalessky district of Vladimir Province. The texts were documented mainly in the last third of the nineteenth and first third of the twentieth centuries. The author analyzes the themes and typical elements of wedding decrees; reveals the formulas and phrases that were borrowed from humorous “Dowry Lists”; and describes some their mechanisms of adapting the lubok and folklore repertoire. Dowry lists are oriented on the bride; wedding decrees, while retaining some focus on the bride (giving a parodic characterization of the dowry and the bride’s economic skills), pay even closer attention to the groom. Comparative analysis of wedding decrees demonstrates their mosaic quality and use of formulas, as well as their stylistic similarities to works of democratic satire, lubki, and folklore. While taking dowry lists as the starting point (as E. E. Blomkvist demonstrated, analyzing their themes and constructive principles), the creators of wedding decrees make use of a range of themes relevant to the ritual situation, including material from wedding speeches (prigovory), “koril” songs, Christmas liturgical songs, small genres, and short comic “nebyval’shchiny”; there are also many textual similarities between wedding decrees and works of folk theater (including mummer skits, satirical dramas, and puppet theater).
On the History of Collecting Byliny in the Simbirsk Province
Authors: Иванова Т.Г.
Published: September 2024

В статье обозревается история записи былин в Симбирской губернии. Записи песенного эпоса в этом регионе делались только в XIX в. Большой вклад в собирание былин внесли представители семьи Языковых (Александр Михайлович и Петр Михайлович), владевшие имениями Языково, Станичное и Головино (конец 1830-х  — 1840-е гг.). В с. Усть-Урень и Александровка былины зафиксировал П.В. Шейн (вторая половина 1850-х гг.). Предметом специального внимания является история сел, сохранивших былинное знание. Симбирская былинная традиция — это поздний региональный извод: все селения Симбирского края, в которых записывались былины, были основаны не ранее середины XVII в. Социальный статус селений гораздо более разнообразный, чем крестьянские деревни Русского Севера, не знавшие крепостничества. В Симбирской губернии былины записывались в городах (Симбирск, Сызрань). Основание ряда поселений служивыми казаками позволяет предположить, что первопоселенцы приносили с собой во вновь осваиваемые места песенный эпос. По всей вероятности, песенно-эпическое знание несли с собой и крестьяне, переводимые помещиками на новые пожалованные им земли. Особо подчеркнем, что в Симбирской губернии, в отличие от Русского Севера, былина пелась в крепостной деревне (Языково, Усть-Урень, Александровка, Станичное, Головино). Как следует из истории симбирских сел, многие из них были старообрядческими (Ярыкла, Головино).

This article reviews the history of transcribing epics (byliny) in Simbirsk Province. In this region writing down byliny was first done in the nineteenth century. Alexander Mikhailovich and Peter Mikhailovich Yazykov, who owned the estates of Yazykovo, Stanichnoye and Golovino in the late 1830s — 1840s, made a great contribution to their collection. In the second half of the 1850s, P. V. Shein recorded byliny from Ust-Uren and Aleksandrovka. The history of settlements that preserved the performance of byliny is a subject of special interest. The Simbirsk epic tradition was a late regional development: all of the villages of the Simbirsk region in which byliny were recorded were founded no earlier than the middle of the seventeenth century. The social composition of these villages was much more diverse than the peasant villages of the Russian North, which had not known serfdom. In Simbirsk Province, epics were written down in cities (Simbirsk and Syzran). A number of settlements founded by Cossacks in service suggests that settlers brought song epics with them to their new homes. In all probability, serfs who were transferred by their owners to lands they had been granted also brought the tradition with them. We should note that in Simbirsk province, unlike in the Russian North, byliny were sung in serf villages (Yazykovo, Ust-Uren, Alexandrovka, Stanichnoye and Golovino). As we learn from the history of Simbirsk settlements, many of them were populated by Old Believers (like Yarykla and Golovino).
Startsev Corner: On the Border of Regions and at the Intersection of Legends
Authors: Шеваренкова Ю.М.
Published: September 2024

Базой исследования служат материалы фольклорных экспедиций ННГУ им. Н.И. Лобачевского в Сеченовский район Нижегородской области и Большеигнатовский район Республики Мордовия. Объект исследования  — почитаемый у русских и мордвы природный комплекс Старцев Угол, расположенный на нижегородской стороне, у границы с Мордовией. Легендарная основа комплекса — образ утраченного монастыря, материальными заместителями которого выступает триада: холм  + родники + камни. Цель исследования  — определить пространственную и семантическую структуру комплекса, статус и роль его природных единиц, закрепившиеся за ними ритуальные практики, обозначить сюжетный фонд местных легенд. Первичным пластом местных нарративов являются предания об Иване Грозном как основателе монастыря и Емельяне Пугачеве как его разрушителе. Образ бывшего монастыря стал основой нарративов о его провале/сожжении/погребении. Версия о провале базируется на представлении о сокрытии монастыря под землей и его подземной жизни, включает традиционные мотивы «вестей» из-под земли, соотносится с идеей будущего «выхода» церкви из-под земли. Версия уничтожения монахов позволяет рассматривать Старцев Угол как могилу. Пространственную структуру урочища образуют холм, пять источников и группа камней. Посещение урочища носит медицинский и поминальный характер. Расположение урочища на месте исконных мордовских земель позволяет предполагать наличие здесь утраченного археологического объекта — мордовского поминального кургана.

This article is based on materials collected by folklore expeditions from the Lobachevsky State University to the revered natural complex of Startsev Ugol, located on the border of the Nizhny Novgorod region and Mordovia. The legendary basis of the complex is as a lost monastery, the material remnants of which are the triad of hill + springs + stones. The study attempts to determine the spatial and semantic structure of the complex; the status, role and ritual practices connected with its natural components; and to describe the plot fund of local legends. The primary layer of these narratives is a legend about Ivan Grozniy as the founder of the monastery and Emelyan Pugachev as its destroyer. The image of the one-time monastery constitutes the basis for narratives about its failure, burning, or burial. The version about its failure is based on the idea of hiding the monastery underground and its life there; the story includes traditional motifs of “news” from underground and correlates with the idea of the church’s future “exit” from underground. The version about the killing of its monks suggests the image of Startsev Ugol as a grave. Startsev Ugol’s spatial structure is formed by a hill, five springs and a group of stones. People visit Startsev Ugol for medical nature and memorial reasons. The location of the tract on the site of ancestral Mordovian lands suggests the presence here of a lost archaeological site — possibly a Mordovian funeral mound.
The Great Martyr Panteleimon: Heavenly Healer and “Punisher with Thunder and Lightning”
Authors: Некрылова А.Ф.
Published: September 2024

В статье речь идет о народном восприятии популярного христианского святого великомученика Пантелеймона. На основное — житийное — осмысление святого как целителя, небесного покровителя всех болеющих, а также лекарей наложилось представление о Пантелеймоне как о грозном святом, который может наслать грозу с молниями и ливнями, что приводило к гибели урожая. Фольклорным именованиям святого (Паликопна, Палий) способствовала не только дата празднования святого (время сильных летних гроз), но и законы народной этимологии. Приводятся примеры обращения к святому в заговорах, а также обрядовые действия, долженствующие умилостивить святого, выступить его в качестве заступника, целителя и одновременно карающей силы.

This article deals with the perception of the popular Christian saint Panteleimon the Great Martyr. The main hagiographical understanding of the saint as a healer, the heavenly patron of sick people as well as healers, was overlaid with the idea of Panteleimon as a powerful saint who could send a thunderstorm with lightning and showers, which could lead to the destruction of the harvest. Folkloric names of the saint (Palikopa, Paliy) not only contributed to the date of the saint’s celebration during the time of summer thunderstorms, but also suggested their popular etymology. The article cites appeals to the saint in zagovory (charms), as well as ritual actions aimed to propitiate the saint, appealing to him as intercessor, healer, and — at the same time — as a punishing force.
The Birth of Nationalism from Rural Landscape
Authors: Tyas Agnes Siwi Purwaning
Published: September 2024

This paper aims to explore the significance of portraying space in narrating the independence war struggle of Indonesians people from the perspectives of film studies. In the absence of war documentaries, Japanese made newsreels produced by Nippon Eigasha Djawa or Japan Motion Picture Indonesian branch can present alternative images to discuss the war struggle. When filming the people, attention was also given to the portrayals of the space, which tend to receives less sufficient attention from the public. Nonetheless, it plays a vital role in offering a fresh viewpoint on how rural areas transform into battlefields. The study employs analysis of both visual and textual texts inside the news-documentary films to discuss three points pertaining to rural landscapes: (1) the representations of space in the films (2) the forms of interaction between space and society, and (3) the forms of activities taking place in the space in regards to independent struggle and nation founding.
Nanoplastic-induced Disruption of DPPC and Palmitic Acid Monolayers: Implications for Membrane Integrity
Authors: Proma Shamma Jabeen , Biswas Biswajit , Allen Heather C.
Published: September 2024

Nanoplastics are generated from the fragmentation of microplastics under various environmental conditions in the atmosphere. These tiny pollutants are widespread and can enter the human body through the air we breathe and the food and water we consume. Understanding how nanoplastics interact with different membrane lipids is paramount to discerning the kind of threat they pose in terms of lung alveolar destabilization, impaired cell communication, cell wall disruption, diminished nutrient delivery, and neurotoxicity. In this research, we examined the interaction of polystyrene nanoplastics with palmitic acid and phosphatidylcholine at the air-aqueous interface to identify individual lipid response. Employing a comprehensive experimental approach that includes infrared-reflection absorption spectroscopy (IRRAS), Langmuir isotherms and Brewster angle microscopy (BAM), we investigated chemical and physical changes of lipid monolayer systems with nanoplastics dispersed within the water solution phase. Increasing concentration of the polystyrene nanoplastics in the solution phase led to enhanced interfacial activity; the nanoplastics were observed to incorporate into the monolayer driven by lipid adsorption/complexation to the nanoplastics. The findings in this research aid in understanding the physical mechanisms through which nanoplastics may alter and impact biophysical interfaces.
Expedited SARS-CoV-2 main protease inhibitor discovery through modular ‘direct-to-biology’ screening
Authors: Wilders Harry , Biggs George , Rowe Sam , Cawood Emma E. , Rendina Alan R. , Grant Emma K. , Pettinger Jonathan , Fallon David J. , Skehel Mark , House David , Tomkinson Nicholas C. O. , Bush Jacob T.
Published: September 2024

Reactive fragment (RF) screening has emerged as an efficient method for ligand discovery across the proteome, irrespective of a target’s perceived tractability. To date, however, the efficiency of subsequent optimisation campaigns has largely been low-throughput, constrained by the need for synthesis and purification of target compounds. We report a high-throughput platform for ‘direct-to-biology’ (D2B) screening of cysteine-targeting chloroacetamide RFs, wherein synthesis is performed in 384-well plates allowing direct assessment in downstream biological assays without purification. Here, the developed platform was used to optimise inhibitors of SARS-CoV-2 main protease (MPro), an established drug target for the treatment of COVID-19. An initial RF hit was developed into a series of potent inhibitors, and further exploration using D2B screening enabled a ‘switch’ to a reversible inhibitor series. This example of ligand discovery for MPro illustrates the acceleration that D2B chemistry can offer for optimising RFs towards covalent inhibitor candidates, as well as providing future impetus to explore the evolution of RFs into non-covalent ligands.
TOWARDS OPTIMAL PROJECT MANAGEMENT: INFLUENCE OF MONITORING AND EVALUATION PRACTICES ON PROJECT OUTCOMES IN HIV SERVICE PROVISION IN KENYA
Authors: Jacinta Mutie Mwikali , Wambugu Lydia , Nyonje Raphael , Kikwatha Reuben
Published: September 2024

Objective: Quality healthcare service provision is crucial for achieving Sustainable Development Goal 3 on universal health and well-being. However, a noticeable gap exists in the literature regarding the essential role of Monitoring and Evaluation (M&E) practices in planning, data collection, reporting, and results dissemination of Human Immunodeficiency Virus (HIV) services. The objective was to investigate extent to which the perceptions of healthcare workers influence on M&E practices.
 
Theoretical Framework: The program theory was applied as it provides a framework for planning, implementation, and evaluation of interventions by identifying the pathways through which these outcomes are achieved. A retrospective cross-sectional survey design was used as it leverages complementary methodologies. The high consensus levels highlighted the universality of this perspective within the healthcare community. A moderate positive correlation and a significant relationship between the two variables was observed. Theoretically, it showed how the perceived contribution of M&E offers a conceptual framework for analyzing and evaluating interventions toward project effectiveness.
 
Results and Discussion: Variations in healthcare infrastructure, resources, and patient demographics across regions could influence the applicability of the results. The practical, methodological and theoretical implications of this research provide insights into how the results can be applied.
 
Research Implications: This study contributes to the literature through practical contributions by identifying progress and challenges throughout the healthcare system to provide.
 
Originality/Value: The relevance and value of this research are evidenced by guiding stakeholders, project managers and implementers in improving their M&E systems, allowing for better resource mobilization, and planning, by documenting and replicating successful interventions.
E Rere Ana Te Wai O Waikato He Piko He Taniwha, He Piko He Taniwha
Authors:   , Muru-Lanning Henry
Published: September 2024

The Waikato River is a significant cultural and historical water body for Waikato Māori, who view it as a Tūpuna (ancestor), a taonga (treasure), and the embodiment of the mana (authority) and mauri (life force) of Waikato Māori communities. However, since European settlement in the early 19th century, the River’s mauri has been depleted by various human activities such as: land clearance for agriculture, wetland drainage, and land privatisation. This degradation has resulted in restricted access to the River’s edge, wetlands, and culturally significant sites. This has cut peoples’ connections to the awa (river) and landscape, therefore resulting in a weakened sense of mauri, mana and hauora (well-being) for the River and everything which whakapapa (relate as kin) to it. The site selected for this study sits on a bend of the River. It has many important tribal landmarks on and around it - and had Māori settlement on it prior to settler-government confiscation of the land in the 1870s. Adding to the depleted mauri and hauora of this landscape is that the land is now all held in individualised parcels used for lifestyle blocks and is prone to serious flooding.

Currently there is a lack of research surrounding mauri in landscape architecture, with most literature regarding mauri through a social studies, legislature, and scientific lens. There are restoration projects, and some landscape architecture designs in New Zealand which deal with mauri, but these projects mainly aim at restoring mauri through re-introducing/ creating habitat for native and taonga species, through symbolism and through community engagement. There is little discussion on the socio-experience surrounding mauri.

My proposal seeks to rethink and recreate a settlement on the banks of the Waikato River that will improve mauri and reconnect all people especially members of my Whānau/Iwi, with their whenua and the River. I will do this by reasserting the mana of the River which will include: 1) establishing new places, spaces and homes for people; 2) creating new habitats for flora and fauna; and 3) re-reconnecting people with the River by creating a new eco-settlement with public spaces and wetlands. These features will weave the settlement together figuratively and literally. By integrating Maatauranga Māori (Māori knowledge) with landscape architecture, the research and proposed design aims to improve water quality, enhance ecological biodiversity, reduce flooding and emphasise the cultural and spiritual significance of the River. Importantly, my proposal will enhance the mauri of the River by reclaiming its flood plain, and creating a sense of connection between all living and non-living things located at the site.
Worrying increase in the risk of vertical transmission of syphilis in Croatia, 2020 to 2024
Authors: Nemeth Blažić Tatjana , Krajcar Nina , Kosanović Ličina Mirjana Lana , Ljubas Dominik , Mardh Otilia , Božičević Ivana
Published: September 2024

Four infants potentially exposed to syphilis infection in utero, meeting World Health Organization surveillance criteria of congenital syphilis (CS), were diagnosed in Croatia between September 2020 and January 2024. We conducted a retrospective analysis of epidemiological, clinical and laboratory data of these cases to assess compliance with surveillance case definitions. As only one confirmed CS case has been reported in Croatia in over 2 decades, these reports signal an increased risk of syphilis vertical transmission and warrant strengthening antenatal screening.
Proposta de reorganização de layout em uma microempresa familiar do ramo de restaurantes: uma aplicação do diagrama de espaguete com o software Edrawmax
Authors: Cardoso Ingrid Machado , Pojo Daniel Maia , Martins Harley dos Santos
Published: September 2024

Este artigo discute a importância de organizar o espaço físico em uma microempresa para melhorar os processos de trabalho. Destaca-se que isso é relevante não apenas para grandes indústrias, mas também para pequenos negócios, como restaurantes. Com base em pesquisas anteriores, foram selecionadas ferramentas apropriadas para diagnosticar os problemas de layout. O software Edrawmax, em conjunto com o diagrama de espaguete, foi utilizado para analisar os processos, identificar a problemática e propor melhorias para mitigar os problemas identificados. A partir desse diagnóstico, foram elaboradas ações direcionadas para soluções práticas, com o objetivo de promover um melhor desenvolvimento das atividades. Observou-se que essas medidas resultaram em uma redução significativa de aproximadamente 62,86% na distância percorrida durante o processo de preparo de todas as refeições. Para orientar as ações necessárias para a reorganização do layout, foi adotada a ferramenta 5W2H, que oferece uma abordagem sistemática e eficaz para auxiliar nesse processo. Essa ferramenta ajuda a responder a questões-chave que proporciona um plano claro e detalhado para melhorar os processos de trabalho na microempresa.
Manual de Intervenção Motora no TEA
Authors: Mendonça Eliana da Silva Coelho , Costa Robson Antonio Tavares
Published: September 2024

Este videobook foi desenvolvido com o objetivo de enriquecer e incentivar a prática de atividades motoras para crianças e adolescentes diagnosticados com Transtorno do Espectro Autista (TEA). Reconhecendo a importância do desenvolvimento motor na qualidade de vida e no progresso terapêutico desses jovens, o videobook oferece uma abordagem abrangente e prática.

A obra é estruturada em torno das três principais categorias de habilidades motoras essenciais para o desenvolvimento funcional e social: habilidades manipulativas, habilidades locomotoras e habilidades estabilizadoras. Cada categoria é explorada de forma detalhada, com sugestões práticas e atividades adaptadas às necessidades e capacidades dos indivíduos com TEA.

Habilidades Manipulativas: Estas atividades envolvem o controle e a coordenação dos movimentos das mãos e dos dedos, essenciais para tarefas diárias e para o desenvolvimento da destreza manual.

Habilidades Locomotoras: Estas atividades incluem movimentos fundamentais como correr, saltar e caminhar, que são cruciais para a mobilidade e para a interação com o ambiente.

Habilidades Estabilizadoras: Estas atividades visam o fortalecimento do equilíbrio e da postura, fundamentais para a realização de tarefas de forma segura e eficiente.

O videobook é projetado para fornecer um recurso valioso tanto para profissionais, como terapeutas e educadores, quanto para familiares, oferecendo orientações claras e estratégias eficazes para a implementação das atividades motoras. Através de uma abordagem sistemática e bem fundamentada, o material busca não apenas promover o desenvolvimento motor, mas também fomentar a autonomia e a inclusão social dos jovens com TEA.

Ao combinar teoria e prática, este videobook representa uma ferramenta indispensável para aqueles que buscam apoiar o desenvolvimento motor de crianças e adolescentes com TEA, proporcionando-lhes oportunidades para crescer e prosperar em um ambiente de aprendizado e apoio contínuo.
Elitization: Mainsprings of Elite Social Control of Local Politics in Cameroon
Authors: Bombela Jean Daniel Bombela
Published: September 2024

Abstract: In Cameroon, development priorities and the need to ensure social peace have led to the emergence of elites as social relays for community grievances within the state apparatus. The legitimacy of their role entails the conversion of political and administrative positions into resources. Based on data collected from a field survey, this article shows how those who gain access to the status of state nobility build their legitimacy. It postulates that political-administrative promotion is not enough to transform an individual into an elite: he must build his elitism. That is why I put forward the hypothesis of elitization, understood as a process of conjunctural legitimization of elite status.
Implicit and explicit forms of memory among children with high-functioning autism spectrum disorder
Authors: Sangeetha S R  , Patteswari Duraisamy  , Meghana A R  , Swetha Sivakumar
Published: September 2024

The purpose of this study is to investigate children with high-functioning autism spectrum disorder and their implicit and explicit memory capacities to develop personalized educational and rehabilitative programs. Children with high-functioning ASD have much less explicit memory, but their implicit memory is still mostly intact, according to the research. The study highlights how employing verbal materials for encoding and other memory support can improve performance. Moreover, it emphasizes how critical it is to recognize and treat episodic memory problems in children with ASD, opening the door to more successful interventions catered to their requirements. By identifying the distinctive memory traits of children with high-functioning autism spectrum disorders, the study's implications are critical for improving cognitive performance in this population.
Strategic management in emerging markets: Challenges and opportunities
Authors: Obianuju Clement Onwuzulike  , Munachi Ijeoma Ononiwu  , Kazeem Shitu
Published: September 2024

This study examines the intricacies of strategic management within emerging markets, focusing on the challenges, opportunities, and strategic frameworks essential for success. Through a comprehensive literature review and analysis of case studies, the study explores how businesses can navigate the unique environments of emerging markets, characterized by dynamic growth, institutional voids, and diverse cultural landscapes. Key findings highlight that while emerging markets present significant challenges, such as political instability, economic volatility, and resource constraints, they also offer substantial opportunities for growth, innovation, and market expansion. Strategic tools like SWOT analysis, PESTEL analysis, and the Resource-Based View have proven effective in addressing these challenges, while trends such as digital transformation, sustainability, and the rise of emerging market multinationals are poised to shape the future of strategic management in these regions. The study provides practical recommendations for practitioners, emphasizing the importance of flexibility, innovation, and local adaptation. For policymakers, the study suggests a focus on strengthening institutional frameworks and supporting sustainable business practices to create a more conducive environment for businesses. In conclusion, this research offers valuable insights and recommendations for businesses seeking to capitalize on the opportunities within emerging markets, highlighting the need for continued exploration of evolving trends such as digitalization and sustainability to ensure the relevance and effectiveness of strategic management practices in the increasingly globalized economy.
Addressing Supply Chain Inefficiencies to Enhance Competitive Advantage in Low-Cost Carriers (LCCs) through Risk Identification and Benchmarking Applied to Air Australasia’s Operational Model
Authors: Babatunde Olusola Awotiwon  , Joy Onma Enyejo  , Fadekemi Rukayat Adedoyin Owolabi  , Idayat Ninilola Ololade Babalola  , Toyosi Motilola Olola
Published: September 2024

This study examines the issues in Air Australasia’s supply chain operations as a leading low cost carrier (LCC) in the market. It delves into the inefficiencies within the airlines supply chain that affect its operational efficiency and competitiveness. The goal of this research is to pinpoint key areas of inefficiency and suggest strategies for enhancing the airlines operational effectiveness and competitive edge. The study’s population includes individuals engaged in managing the airlines supply chain like supply chain managers and logistics coordinators among others. A group of 25 participants was purposefully selected to gain a thorough understanding of how the airline manages its supply chain processes. The research uses a blend of qualitative and quantitative methods and Data was gathered through organized interviews surveys and by examining internal documents such, as financial reports and operational records. The researchers looked closely at the data to find common themes and used statistical techniques to analyze the quantitative data for patterns and relationships between variables. Their discoveries pointed out weaknesses in procurement processes and logistics coordination as well as issues with risk control. They provided recommendations on how Air Australasia could enhance its edge by implementing stronger risk assessment strategies and align its supply chain operations with industry norms for better performance and sustainability over time. The research adds to our knowledge of how supply chains work in the low cost carrier (LCC) industry and offers advice for businesses looking to improve their operations efficiently. These suggestions focus on streamlining supply chain operations and improving customer satisfaction to help Air Australasia stay competitive in the LCC market.
Innovative design solutions for social housing: Addressing the needs of youth in Urban Nigeria
Authors: Andikan Udofot Umana  , Baalah Matthew Patrick Garba  , Abayomi Ologun  , Johnson Segun Olu  , Muritala Omeiza Umar
Published: September 2024

This study explores the development of youth-centric social housing in Nigeria, addressing the critical need for innovative and sustainable housing solutions tailored to the nation's growing youth population. The purpose of this study is to analyze the multifaceted challenges associated with housing development, including economic, technological and environmental considerations, and to propose strategies that can enhance the affordability, sustainability, and resilience of youth-centric housing projects. Employing a comprehensive review of relevant literature and case studies, the study examines key implementation strategies, stakeholder engagement practices, and policy frameworks that can support the successful deployment of such housing initiatives.
The main findings of this study emphasize the importance of integrating renewable energy technologies, smart housing systems, and circular economy principles into housing designs to reduce costs and environmental impact. The study also highlights the necessity of robust IT governance, forensic accounting and legal frameworks to ensure transparency, security, and compliance in housing projects. The socioeconomic impacts of youth-centric housing are also analyzed, revealing significant potential for enhancing economic opportunities, promoting social cohesion and fostering environmental sustainability.
In conclusion, the study affirms that a holistic approach is required to address the housing needs of Nigeria’s youth, combining technological innovation, strong governance, and active stakeholder engagement. The study recommends that policymakers and stakeholders prioritize the development of integrated strategies that leverage financial technology, renewable energy, and smart technologies, while ensuring robust governance and legal compliance. These efforts are essential for creating sustainable, resilient and inclusive communities that can meet the evolving needs of Nigeria's youth, thereby contributing to the nation's long-term development goals.