bluuebunny/crossref_metadata_2025 huggingface dataset:
Milestone Developments and New Perspectives of Nano/Nanocrystal Light Emitting Diodes
Authors: Singh Jyoti , P. Borane Niteen , Boddula Rajamouli
Published: December 2022

Light emitting diode (LED) is a one type of p/n junction semiconductor device which is used in less energy consumption for numerous lighting functions. Because of their high performance and long existence, their eye-catching application is getting increasing numbers in recent times. LEDs are nowadays defined as using the “ultimate light bulb”. In a previous couple of years, its efficiency has been multiplied through converting it to nano size. This new light-emitting has a nano-pixel structure and it affords high-resolution performance and the geometry of the pixel is cylindrical or conical form. Due to the fact that the previous few years, a few impurity-doped nanocrystal LEDs are varying a good deal in trend. Its performance is very excessive and consumes a smaller amount of voltage. Its monochromatic behavior and indicator excellent are shown publicly demanded in the market and in this work, it’s covered evaluations of the fundamental’s standards of LEDs and the specific mixed metallic and nanocrystal shape of emitters. In addition, it covers the upcoming challenges that the current trend is working to resolve to get efficient materials to fulfill the future energy crisis.
Effect of Educational Intervention Based on PRECEDE Model on Improving Menstrual Health Behaviors Among Female Students
Authors: Rezaei Mohammadali , Solaimani Laleh , Mohammadinia Neda
Published: December 2022

Background: Poor menstrual health is a risk factor for genital infections and infertility. It may affect family health and the community’s future. Objectives: This study aimed to determine the effect of educational intervention based on the PRECEDE model on improving menstrual health behaviors among female students. Methods: This quasi-experimental study was conducted on 130 first-grade high school female students and their mothers randomly selected from six schools and divided into intervention and control groups. Three two-hour educational sessions were conducted for the students and their mothers in the intervention group based on the pretest results. Data were collected immediately and three months after the educational sessions using a questionnaire with confirmed validity and reliability. Data were analyzed using SPSS v. 21 with repeated-measures ANOVA and t-test. The significance level was considered at 0.05. Results: The educational intervention based on the PRECEDE model increased the mean scores of predisposing, enabling, and reinforcing factors in the intervention group and finally increased the mean score of health behavior immediately (24.1 ± 4.62, P < 0.001) and three months after the intervention (22.84 ± 4.04, P = 0.02) compared to before intervention (19.68 ± 5.48). Conclusions: The results showed a change in factors affecting behavior (predisposing, enabling, and reinforcing factors). The PRECEDE model changed the menstrual health behaviors among the students.
Eros et autobiographie. Ecrire le désir dans les Mémoires d'outre-tombe de Chateaubriand
Authors: Conner Tom
Published: December 2022

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Vom Ideologiebetrieb zur Buch GmbH - Bemerkungen zur Veränderung der Verlagslandschaft in der ehemaligen DDR
Authors: Landin Per
Published: December 2022

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Normandie, terre des Vikings
Authors: Renaud Jean
Published: December 2022

Les Vikings assaillirent l'Europe et le mirent à feu et sang. La Neustrie ne fut évidemment pas épargnée mais, ce qui allait faire l'originalité de la future Normandie, c'est qu'après l'avoir ravagée, les Scandinaves la relevèrent de ses ruines et en firent une puissante province, ancrée sur un double héritage, norrois et franc.
Linguistique contrastive et traductologie
Authors: Eriksson Olof
Published: December 2022

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Aspects of Contemporary American Drama
Authors: Whitley John S.
Published: December 2022

Contemporary Drama
Die Welt als Schlachthaus. Zum Schaffen des Dichters Heiner Müller. Eine Einführung
Authors: Bernhardt Rüdiger
Published: December 2022

Das Drama der Gegenwart
Deux fables de Jean de La Fontaine
Authors: Hedberg Johannes
Published: December 2022

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"El meollo de la tragedia es la esperanza". Entrevista a Antonio Buero Vallejo.
Authors: Åman Kerstin
Published: December 2022

Teatro contemporáneo
Literary History in Literature: An Aspect of the Contemporary Novel
Authors: Hotho-Jackson Sabine
Published: December 2022

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USO DE MÉTODOS ANTICONCEPTIVOS EN ADOLESCENTES DE LA UNIDAD EDUCATIVA BRUNO RACUA DEL MUNICIPIO PORVENIR GESTIÓN 2019
Authors: Roque Callisaya Melany , Llanos  Fajardo Ercilia
Published: December 2022

La anticoncepción en adolescentes constituye uno de los pilares fundamentales para prevenir las consecuencias de la actividad sexual sin protección. El objetivo del presente trabajo es determinar los conocimientos y uso de metodos anticonceptivos en adolescentes de 5° y 6° de Secundaria de la Unidad Educativa Bruno Racua, en la localidad de porvenir, en el departamento de Pando - Bolivia. La investigacion tiene un enfoque cuantitativo de tipo tranversal, descriptivo, con una muetsra de 75 estudiantes, la herramienta utilizada para la recolección de datos fue una encuesta anónima de 14 preguntas. Como resultados, se pudo evidenciar que, 49 % de los adolescentes conoce más de tres anticonceptivos, siendo el condón masculino, los inyectables y la píldora los mas mencionados. De este porcentaje, 37% ya iniciaron una vida sexual activa y solo 25,3% utiliza algun métodos anticonceptivos para evitar embarazos no deseados y las infecciones de transmisión sexual. Una vez realizada la recoleccion y analizados los datos, como forma de mitigar esta situacion, todos los estudiantes recibieron información hacerca del tema en cuestion, tanto por los docentes como por el personal de salud
CARACTERIZACIÓN DE BROTE EPIDÉMICO DE MALARIA POR PLASMODIUM FALCIPARUM EN LA COMUNIDAD DE BUENA VISTA, MUNICIPIO SANTOS MERCADO DE PANDO - BOLIVIA JUNIO 2019
Authors: Crispín Flores Eleuterio
Published: December 2022

El Plasmodium Falciparum es responsable de la forma más grave de la Malaria, trasmitida por los mosquitos anopheles que son frecuentes en la región Amazónica, el objetivo del estudio es caracterizar el brote epidemiológico de malaria por Plasmodium Falciparum en la comunidad de Buena Vista del municipio de Santos Mercado del departamento de Pando-Bolivia en el mes de junio del 2019, los Métodos empleados en el estudio observacional, descriptivo y de corte transversal de pacientes con diagnóstico clínico, laboratorial y epidemiológico por malaria P. Falciparum, en la comunidad de Buena Vista del Municipio de Santos Mercado frontera Bolivia-Brasil. Se realizó entrevistas, revisión de fichas epidemiológicas, reporte de casos e informes de actividades, los Resultados en el estudio, se identificaron 17 casos de malaria por P. Falciparum diagnosticados con prueba rápida y confirmados por gota gruesa, en conclusión, se presentó un número de casos de malaria por P. Falciparum de manera inusual, en una localidad y en un periodo de tiempo. La curva epidemiológica nos permitió describir el número de casos por unidad de tiempo, y definir el 31 de mayo del 2019 como el momento de la exposición
TRANSMISIÓN VERTICAL INTRAUTERINA DEL VIRUS SARS-COV-2 EN LA CIUDAD DE COBIJA GESTIÓN 2020
Authors: Roca Carpio Rutnel
Published: December 2022

La enfermedad de la Covid - 19, es sin duda, una de las crisis sanitarias más grandes de los últimos tiempos; la problemática es más alarmante cuando se da en personas vulnerables, pues las gestantes son un grupo minoritario del total de los casos confirmados y solo se han hecho reducidos estudios al respecto. La investigación tiene como objetivo, Determinar la incidencia de transmisión vertical intrauterina del Virus SARS- CoV- 2 en neonatos internados en el Hospital Covid – 19 Hernán Messuti Ribera de la Ciudad de Cobija, durante el tercer trimestre de la gestión 2020. Dentro de la metodología aplicada se realizó un estudio descriptivo, prospectivo con enfoque cuantitativo y transversal. La Población estuvo constituido por 20 recién nacidos de madres con Covid - 19 Positivo, que estuvieron internadas en el nosocomio. Según los resultados obtenidos el 95% de los neonatos nacieron por cesárea, estos en su mayoría Pre - Término; por otro lado, de acuerdo al tipo de muestra realizada, a un 60% se les tomó la muestra RT-PCR, mediante hisopado nasofaríngeo entre las 16 y 36 horas de vida, un 40% fue tomado a través de las pruebas rápidas; en relación a la incidencia de transmisión vertical, dos recién nacidas (gemelas) asintomáticas dieron positivo para Covid - 19 a través de las pruebas rápidas, las mismas fueron tomadas en el día 8 de nacimiento y no así como dice la normativa, por tanto esta al ser una prueba con valor predictivo reducido es imposible tener evidencia científica que haya existido transmisión vertical
MULTIGROUP ANALYSIS (MGA): PERAN GENDER PADA KUALITAS AUDIT MELALUI ANALISIS VARIABEL KOMPETENSI DAN INDEPENDENSI AUDITOR
Authors: Unkriswina Admin , Astakoni I Made Purba , Nursiani Ni Putu , Utami Ni Made Satya , Sapta I Ketut Setia
Published: December 2022

This study has several objectives: 1) to find out and analyze the effect of auditor competence on audit quality, 2) to know and analyze the effect of auditor independence on audit quality, 3) to know and analyze the role of gender as a moderating effect on the influence of auditor competence on audit quality, 4) to find out and analyze the role of gender as a moderating effect on auditor independence on audit quality. This research was conducted at several Public Accounting Firms (KAP) in Denpasar City with the research subjects being all auditors. The populations in this study were all auditors in the city of Denpasar, amounting to 112 people. Determination of the sample is done by purposive method, so that the numbers of samples selected are 53 auditors. Data collection techniques used were interviews with questionnaires with multiple choices closed. In this study data analysis uses the Partial Least Square (PLS) approach. The results showed that the overall strength of the model was stated to be very good. Hypothesis 1, which states that auditor competence has a significant positive effect on audit quality, can be accepted, Hypothesis 2, which states that auditor independence has a significant positive effect on audit quality, can be accepted. Through multi-group analysis it is stated that gender is able to be a moderating variable on the effect of auditor competence on quality an audit. Whereas gender testing as a moderating variable on the effect of auditor independence on audit quality has not been tested.
COMPARISON ANALYSIS OF INCOME ON ORGANIC VEGETABLE AND INORGANIC VEGETABLES IN AMBON ISLAND
Authors: Leatemia Ester Dorina , Luhukay Johanna M
Published: December 2022

Increasing agricultural production by using chemical fertilizers and pesticides continuously and exceeding the threshold for use will cause new problems for health and the surrounding environment. Organic vegetable farming has been started because people are becoming aware of the dangers of using chemical pesticides. This study aims to describe the characteristics of organic and inorganic vegetable farming, describe the marketing of organic and inorganic vegetables and analyze the comparison of organic and inorganic vegetable farming income on Ambon Island. The method used in sampling is the census method. The results showed that implementation of organic and inorganic vegetable farming in Telaga Kodok Hamlet and Waiheru Village there were differences in vegetable cultivation both in land preparation and processing, seeding, fertilization, and controlling plant pest organisms (OPT). Most farmers (80%) sell organic vegetables to distributors (modern retail markets) when compared to selling vegetables to consumers (20%). The reason farmers sell organic vegetables to distributors (modern retail markets) is they are partners. Farmers in Waiheru Village sell their inorganic vegetable products to retailers (73.32%) when compared to being sold to collectors (13.34 percent) and sold directly to consumers (13.34 percent). The income of organic vegetable farmers is higher (Rp. 2,338,580.29) when compared to the income of inorganic vegetable farmers (Rp. 1,292,187.84). This is due to the difference in the selling price of organic vegetables and inorganic vegetables, and the production costs incurred by organic vegetable farmers are smaller than those of inorganic vegetable farmers.

Keywords: income, marketing, organic vegetables, inorganic vegetables
STRATEGI BAURAN PEMASARAN KERAJINAN TENUN IKAT DI KELURAHAN MAULIRU KECAMATAN KAMBERA KABUPATEN SUMBA TIMUR
Authors: Punju Apri Kaita , Adindarena Vindya Donna
Published: December 2022

Penelitian ini bertujuan untuk mendeskripsikan strategi bauran pemasaran kerajinan tenun ikat yang ada di Kelurahan Mauliru Kecamatan Kambera. Informan penelitian ini adalah pemilik usaha tenun ikat di Kelurahan Mauliru sebanyak 12 orang. Teknik analisis data yang digunakan adalah deskriptif kualitatif. Hasil penelitian menyimpulkan bahwa: (1) Produk berupa kain tenun ikat yang ada di Kelurahan Mauliru dengan indikator produk yaitu keberagaman produk, jaminan dan kualitas. Dari segi keragaman produk bahwa sebagian besar tenun yang dibuat jenis yaitu kain dengan pewarna alam dan kain dengan pewarna wantek, sedangkan jenis kain sebagian besar membuat kain kawuru dan kain kombo, motif yang dibuat diantaranya kuda, ayam, rusa, bunga, naga, dan ana mahang. Dari segi kualitas pewarnanya pakai pewarna alam benang diberi dari toko motifnya berupa gambar ayam dan kuda, sedangkan segi jaminan daya tahannya kuat dan tahan lama. (2) Indikator dari variabel harga adalah penetapan harga yang sesuai dengan kualitas produk dan terjangkau, dimana harga kain tenun ikat pada penenun di Kelurahan Mauliru dalam menentukan harga pertama adalah jenis kain, yang berikutnya pewarnanya alam atau wantek, motifnya yaitu gambar dan tingkat kesulitan dari gambar atau motif tersebut. (3) Indikator tempat yaitu mudah dijangkau, pusat keramaian dan aman, dimana sebagian besar pemilik usaha menjual hasil produknya berupa kain dijual di rumah dan tentu saja di pasar Inpres Matawai sebagai pusat keramaian dan mudah dijangkau sehingga produknya relatif banyak yang laku terjual. (4) Indikator dari promosi yaitu memposting pada media sosial HP, dan dari mulut ke mulut (word of mouth), hal ini sesuai temuan bahwa sebagian besar pemilik usaha dalam menjual hasil produknya selain dijual secara langsung juga dari mulut ke mulut. Selain itu juga melalui media sosial handphone berupa Facebook (Fb) dan WhatsApp (WA).
PENGARUH PAD DAN BELANJA MODAL TERHADAP PDRB KABUPATEN DI PULAU SUMBA TAHUN 2015 - 2020
Authors: Ama Defresto Risman Tamu , Renggo Yuniarti Reny
Published: December 2022

Penelitian ini bertujuan untuk mengetahui pengaruh PAD, Belanja Modal terhadap Produk Domestik Regional Bruto Kabupaten di Pulau Sumba Tahun 2020.  Teknik pengumpulan data dengan menggunakan data sekunder yaitu dari website resmi Badan Pusat Statistik Provinsi NTT. teknik analisis data yang digunakan adalah Teknik Regresi Data Panel dengan pengujian Uji Statistik yaitu Uji R-Square,Uji Simultan dan Uji Parsial. Hasil penelitian menunjukkan bahwa PAD berpengaruh positif tidak signifikan terhadap Produk Domestik Regional Bruto dan Belanja Modal berpengaruh positif signifikan terhadap Produk Domestik Regional Bruto
Pemanfaatan Daun Kemangi (Ocimum Bassilicum L) Terhadap Penurunan Kadar Asam Urat
Authors: Sukeksi Andri , Nuroini Fitri
Published: December 2022

Pendahuluan: Asam urat merupakan hasil akhir metabolisme zat purin yang berfungsi sebagai antioksidan dan membersihkan radikal bebas pada serum. Pengobatan hiperurisemia dapat diatasi dengan cara menghambat aktivitas xantin oksidase menggunakan allopurinol namun dapat menyebabkan beberapa efek samping, sehingga perlu pengobatan alternatif menggunakan kemangi (Ocimum bassilicum L) karena mengandung flavonoid yang dapat menghambat aktivitas xantin oksidase sehingga pembentukkan asam urat menjadi terhambat. Tujuan: Tujuan penelitian adalah mengetahui pengaruh ekstrak kemangi terhadap kadar asam urat. Metode: Jenis penelitian adalah eksperimental dengan rancangan pre and post test design. Sampel penelitian yaitu 6 kelompok Mus musculus dengan kriteria jantan berumur 2-3 bulan dan berat badan 20-30 gram. Kelompok perlakuan diberi ekstrak kemangi dosis 36,4 mg/kgBB, 72,8 mg/kgBB dan 145,6 mg/kgBB. Pengukuran kadar asam urat dengan metode POCT menggunakan alat Multicheck Easy Touch GCU. Hasil: Hasil penelitian menunjukkan kelompok P3 dosis 145,6 mg/kgBB mampu menurunkan kadar asam urat dengan persentase penurunan sebesar 92,06% yang artinya sama efeknya dengan allopurinol dosis 10 mg/kgBB. Kelompok P2 dosis 72,8 mg/kg dan P1 dosis 36,4 mg/kgBB mampu menurunkan kadar asam urat sebesar 55,55% dan 19,04%. Uji Kruskal Wallis menunjukkan ada pengaruh ekstrak kemangi terhadap penurunan kadar asam urat. Kesimpulan: Berdasarkan hasil penelitian dan analisis data yang telah dilakukan, dapat disimpulkan bahwa ada pengaruh ekstrak daun kemangi (Ocimum bassilicum L) untuk menurunkan kadar asam urat darah Mus musculus pada kondisi hiperurisemia
Meningkatnya hasil belajar siswa di lingkungan Global Islamic Boarding School dengan menggunakan PCK dan HOTS
Authors: Amanda Dhea , Karlina Ni Wayan
Published: December 2022

Dalam melaksanakan  pembelajaran seorang pendidik sering mengalami kesulitan dalam menggunakan metode dan model yang sesuai dengan situasi kelas. Era persaingan global saat ini menuntut adanya suatu pembelajaran yang bermutu untuk memberikan fasilitas bagi anak didik dalam mengembangkan kecakapan, keterampilan dan kemampuan sebagai modal untuk menghadapi tantangan di kehidupan global. Dengan pendidik menggunakan cara pedagogical Content knowledge dan High Order Thingking Skills mendapatkan keuntungan baik untuk guru maupun siswa, serta menerapkan literasi numerasi pendidik mampu meningkatkan kompentensi siswa dalam belajar. Hasil pretest  yang di lakukan di Global Islamic Boarding School yaitu 49,0 meningkat  nilai post-test menjadi 57,04 . Sedangkan Numerasi yaitu dari 30,12 meningkat menjadi 49,58. Dengan adanya peningkatan nilai dari siswa, pendidik mampu meningkatkan cara agar siswa mampu menerima materi dengan baik serta mudah dipahami.
Abstract. In carrying out learning an educator often has difficulty in using methods and models that are appropriate to the classroom situation. The current era of global competition demands quality learning to provide facilities for students to develop skills, and abilities as capital to face the challenges of global life. With educators using pedagogical Content knowledge and High Order Thinking Skills, they get benefits for both teachers and students, and applying numeracy literacy educators are able to improve student competence in learning. The results of the pretest conducted at the Global Islamic Boarding School, which was 49.0, increased the post-test score to 57.04. Meanwhile, the Numeration from 30.12 increased to 49.58. With an increase in the value of students, educators are able to improve the way that students are able to receive material well and easily accessible.
Hasil belajar dan keterampilan berpikir kritis peserta didik menggunakan LKPD-elektronik konsep virus
Authors: Adawiyah Rabiatul , Zaini Muhammad , Ajizah Aulia
Published: December 2022

Hasil belajar kognitif dan keterampilan berpikir kritis peserta didik harus ditingkatkan oleh lembaga pendidikan pada masa pandemi COVID-19. Kegiatan pembelajaran yang dilaksanakan secara online perlu diintegrasikan dengan kecenderungan berpikir kritis. Penelitian ini bertujuan untuk menganalisis pengaruh penggunaan LKPD-Elektronik terhadap hasil belajar kognitif produk dan kognitif proses pada konsep virus, dan pengaruhnya terhadap peningkatan keterampilan berpikir kritis. Penelitian hasil belajar kognitif produk dan kognitif proses menggunakan penelitian quasi eskperiment dengan teknik purposive sampling, sedangkan keterampilan berpikir kritis menggunakan kelas perlakuan dan kontrol. Teknik analisis data hasil belajar menggunakan analisis kovarian dianalisis dengan uji Statistical Product and Service Solutions (Program SPSS 22). Data keterampilan berpikir kritis dianalisis melalui teknik deskriptif dengan penskoran kategorisasi. Hasil penelitian menunjukkan LKPD-Elektronik berpengaruh signifikan terhadap hasil belajar kognitif produk dan kognitif proses dengan signifikansi  0,000, dan aspek keterampilan berpikir kritis dengan rata-rata kategori baik. Keterampilan berpikir kritis bermanfaat bagi peserta didik memahami materi pelajaran dan menempatkan diri dalam kehidupan sehari-hari.
Abstract. Educational institutions must improve cognitive learning outcomes and students' critical thinking skills during the COVID-19 pandemic. Learning activities carried out online need to be integrated with critical thinking tendencies. This study aims to analyze the effect of electronic worksheets on product cognitive learning outcomes and cognitive processes on the concept of viruses and their effect on increasing critical thinking skills. The research on product cognitive learning outcomes and cognitive processes used a quasi-experimental study with a purposive sampling technique, while critical thinking skills used treatment and control classes. The data analysis technique for learning outcomes uses covariance analysis through the Statistical Product and Service Solutions test (SPSS 22 Program). Critical thinking skills data are analyzed with descriptive techniques with categorization scoring. The results showed that LKPD-Electronic significantly affected product cognitive learning outcomes and cognitive processes with a significance of 0.000, and aspects of critical thinking skills with an average of good categories. Critical thinking skills are helpful for students to understand the subject matter and place themselves in everyday life.
Couples who Collaborate: Chana and Larry Stiefel
Authors: Sableski Mary-Kate
Published: December 2022

Chana and Larry Stiefel are new to publishing as a couple but bring with them a wealth of diverse experiences. Chana has written and published more than thirty books for children. She writes both fiction and nonfiction, ranging in topics from avocadoes to zombies. Recently, Let Liberty Rise (2021) was named a Bank Street Best Book for Children (ages 5–9) and received a starred review in School Library Journal. Her forthcoming book, The Tower of Life: How Yaffa Eliach Rebuilt her Town in Stories and Photographs (2022) is a Junior Library Guild Gold Standard Selection, and received a starred review from School Library Journal.
President’s Address: Celebrating Effective Practices
Authors: Koester Amy
Published: December 2022

In a conversation recently with members of the Association of Children’s Museums (ACM), we discussed our associations, our members, and the work we do for our communities. We talked about how we share the great examples of programs and services that different members offer in their unique settings.I immediately connected to the terminology that ACM uses—“effective practices.” This is an intentional alternative to “best practices,” which implies practices that have been formally evaluated in some way—rigorously tested, evidence-based practices that are “best” in their area.
Public Awareness and Advocacy Committee: Making the Invisible Visible: EDI Is More Than a Buzzword
Authors: Aspiazu Alex
Published: December 2022

Antiracism and antidiscrimination work requires all of us to try our hardest to question and dismantle systems of inequality that have been in place for so long that we don’t notice them in the day to day. The key is to make any invisible hardships that we notice visible, especially if we are not in the group affected by them, and begin the work of rectifying those imbalances. This is at the heart of EDI—which stands for equity, diversity, and inclusion initiatives and practices.
Out of Many, One: Practicing Defensive Librarianship
Authors: Walters Jayne
Published: December 2022

Fifty-two books in Utah’s Alpine School District. Forty-three books in Oklahoma. Thirty books in Kansas. Four hundred sixty five books in Pennsylvania’s Central York School District; 204 books in Florida; 713 books in Texas, with 435 bans in North East Independent School District. Eight hundred books in Texas legislator Matt Krause’s list of books for investigation. The list goes on, the numbers go up, almost all exclusively targeting books by and about people of color and members of the LGBTQIA+ community.While censorship has long been an issue for libraries, this past year has brought a record number of ban requests across the nation—more than fifteen hundred tracked by PEN America between July 2021 and March 2022. Libraries are also becoming sites for protest—against Drag Queen Story Times, appearances by BIPoC and queer authors, Rainbow Clubs for teens, and other inclusive programming.
Analysis of genetic diversity in two plantations of Pinus caribaea var. hondurensis
Authors: Schmid Patricia Griselda , Garcia Martin Nahuel , Gauchat Maria Elena , Scherer Rafael , Reis Hugo Daniel , Gallo Leonardo , Poltri Susana Noemi Marcucci
Published: December 2022

Forest tree breeding activities in plantations with exotic species implies several instances of material selection where genetic variation can be affected. The objective of the work was to verify the genetic variability present in two plantations of Pinus caribaea var. hondurensis by microsatellite markers, initially designed for Pinus taeda fluorescent-labeled. Thus, 299 individuals were analyzed using eight polymorphic microsatellite markers. The results indicate that both plantations have adequate levels of genetic diversity that are representative of the Pinus genus. Through the Bayesian method, it was possible to detect two different population genetic structures (K = 2) between both plantations analyzed. In conclusion, this study suggests that microsatellites markers are useful tools to monitor genetic variation in genetic breeding programs. The genetic diversity estimated in both plantations is similar and typical for Pinus plantations, and as expected, there was a slight decrease in genetic variability in the commercial plantation in comparation with the base plantation.
Existe dormência física em sementes de Psidium cattleianum Sabine?
Authors: Lopes Betel Cavalcante , Sá Alexandra Cristina , Corrêa Bruno Jan , Dambros Vanessa Giseli , Oliveira Luciana Magda de
Published: December 2022

Objetivou-se com o trabalho avaliar a presença de dormência física em sementes de Psidium cattleianum (araçá), obtidas de frutos de diferentes estádios de maturação. Os frutos foram coletados em 15 plantas matrizes no município de Lages-SC e classificados, de acordo com a tabela de cores de Munsell, em vermelho amarelado (5YR5/7), vermelho (10R5/6) e vermelho escuro (10R3/6). Após o beneficiamento, com auxílio de peneira e água corrente, as sementes dos frutos das três colorações foram avaliadas quanto: teor de água, massa seca, primeira contagem de germinação, germinação, plântulas anormais, sementes mortas, primeira contagem de emergência, emergência, dias para iniciar a emergência, índice de velocidade de emergência, curva de embebição em água e embebição em azul de metileno. Os teores de água estavam em 22,02; 23,53 e 23,08% para as sementes das colorações 1, 2 e 3, respectivamente. Não houve diferença significativa entre as sementes dos frutos das três colorações para todas as variáveis analisadas, exceto para o índice de velocidade de emergência, em que sementes de frutos da coloração 2 demonstraram-se mais vigorosas em relação às sementes das demais colorações. O processo de embebição em água foi caracterizado por uma curva trifásica, com início da protrusão radicular em 275, 323, 323 horas, para sementes de frutos de colorações 1, 2 e 3, respectivamente. Observou-se entrada do azul de metileno nas sementes já no primeiro dia, com absorção completa em 371 h (16 dias). Com base nos resultados obtidos, verifica-se que as sementes das três colorações do fruto já estavam na maturidade fisiológica, com resultados semelhantes em relação à massa seca. Conclui-se que sementes maduras de Psidium cattleianum Sabine não possuem dormência física, independente da coloração dos frutos estudados.
A influência da palmeira-leque-da-china na regeneração da Floresta Ombrófila Densa Montana na Serra da Cantareira, SP
Authors: Mangolini Tânia Girão , Arzolla Frederico Alexandre Roccia Dal Pozzo
Published: December 2022

A Floresta Ombrófila Densa Montana pertence ao domínio da Mata Atlântica, um importante hotspot de biodiversidade. No Brasil, a maioria dos casos de invasões biológicas deve-se a plantas terrestres, sendo essa formação vegetal a que apresenta o maior número de ocorrências. Nesse contexto está o Parque Estadual da Cantareira (PEC), em São Paulo. O PEC abriga um remanescente que apresenta focos de invasão por espécies exóticas, entre elas Livistona chinensis (N.J.Jacquin) R.Brown ex Mart., a palmeira-leque-da-China. Devido ao potencial de invasão dessa espécie, foi conduzido um estudo florístico-fitossociológico sobre o efeito de inibição da regeneração natural do componente arbóreo por indivíduos jovens de Livistona chinensis, com alturas de 3 e 6 m. Para cada palmeira, foram instaladas 8 parcelas de 1 x 1 m, distribuídas dentro de quatro quadrantes, tendo a estipe da palmeira ao centro, de forma que metade das parcelas ficaram localizadas embaixo da copa e metade ao redor. Na análise foram considerados os espécimes arbóreos e de palmeiras com altura ≥ 20 cm e com Perímetro à Altura do Peito (PAP) ≤ 15 cm. Os resultados apontaram uma drástica redução do número de indivíduos regenerantes (28,95% e 29,85% dos indivíduos amostrados) e da riqueza de espécies (16,13% e 8,33% das espécies) ocorrendo sob a projeção das copas dessas palmeiras em comparação com o entorno (71,05% e 70,15% dos indivíduos e 61,29% e 58,33% das espécies, respectivamente). O estudo mostrou o efeito de inibição de indivíduos jovens dessa espécie sobre a regeneração florestal no PEC, ao reduzir substancialmente a riqueza de espécies e a abundância de indivíduos arbóreos sob a projeção das suas copas, possivelmente por servirem de anteparo e causarem o sombreamento excessivo do local.
A Practical Stress Analysis Procedure for Marine Propellers Using Curved Finite Elements
Authors: Atkinson P.
Published: December 2022

The paper concerns the development of techniques which take full advantage of the capabilities of curved finite elements as applied to the problem of stress analysis of marine propellers. The advantages of the proposed techniques are discussed in regard to data generation, analysis and presentation, analysis and presentation results. Hypothetical and conventional propeller forms are analyzed in order to verify and show capabilities of the proposed techniques.
Wyrd TV: Folklore, folk horror and hauntology in British 1970s Television
Authors:   , Rodgers Diane
Published: December 2022

This thesis combines the disciplines of folklore studies and screen studies to examine the on-screen representation of folklore and contemporary legend in 1970s British television texts. Using original interviews with creators of film and television (older participants having worked in the 1970s and younger participants working in present-day media) alongside archive material, the thesis draws out influential examples from the study period that affected those making film and television today. This thesis makes an original contribution to knowledge by employing the notion of mass-mediated ostension, as an approach unique to folklore studies, to examine the cultural context of 1970s British television drama and account for the impact on audiences of unsettling, supernatural and extra-terrestrial stories. The importance of children’s television in this era is also emphasised. This study considers the emergence of folk horror and its resurgence in the post-2000 period, particularly in the work of Generation X creatives, and sets out defining characteristics of ‘hauntological’ and ‘wyrd’ texts. Programme-makers’ reproduction and reinterpretation of folklore and contemporary legend are situated as central to the way such texts are made to seem plausible for an audience. The work of Nigel Kneale is highlighted as having been especially influential in this regard. Screen studies analysis is applied to paradigmatic examples of television programmes (notably Quatermass, 1979, and Children of the Stones, 1977) to assess formal methods and techniques used to represent folkloric and contemporary-legend motifs. In conclusion, this thesis reflects upon the continuing influence of 1970s folkloric television texts: how this remains manifest in British media and how it shapes the communication of folklore and the future of the folk-horror genre itself.
Incentivos y riesgos fiscales y laborales de las Sociedades Cooperativas de Producción en México
Authors: Carmona López Antonio Maximino , Ruíz Martínez Alfredo , Ramos Soto Ana Luz
Published: December 2022

El objetivo del presente trabajo de investigación es analizar los incentivos fiscales y el financiamiento público destinado al fomento de las Sociedades Cooperativas de Producción en México, así como la participación de las cooperativas en actividades que puedan representar transgresiones a las leyes fiscales y laborales de nuestro país. Los resultados muestran que la crisis económica de la década de los ochenta del siglo pasado obligó al cambio del modelo económico y las cooperativas fueron relegadas de las políticas públicas. La relación con el Estado se fracturó nuevamente en el año del 2013 cuando se imputaron a las empresas cooperativas la realización de operaciones fraudulentas para omitir el pago de contribuciones federales, como consecuencia, se eliminaron los regímenes especiales de tributación y se redujo el financiamiento público. Sin embargo, la información publicada por las autoridades administrativas del país no aporta evidencias empíricas para asegurar que en los últimos 11 años las organizaciones cooperativas constituyan un factor de riesgo para la hacienda pública federal y la estabilidad laboral de los trabajadores. La presente investigación aplica un enfoque mixto, lo que significa la combinación de métodos y técnicas de las investigaciones del tipo cuantitativo y cualitativo. En el primer caso se recurre al método hipotético deductivo y en el segundo a la teoría fundamentada y a la triangulación hermenéutica. Los datos provienen de la página electrónica de las agencias gubernamentales y la consulta directa al instituto responsable de proporcionar la información pública a los ciudadanos.
La nueva reserva de contratos públicos de servicios sociales, culturales y sanitarios en España a cooperativas de trabajo asociado, sociedades laborales y asociaciones
Authors: Comet-Herrera David
Published: December 2022

Las actuales normativas europea y española reguladoras de los procedimientos de contratación pública han ampliado la posibilidad de reservar la gestión de determinados servicios públicos, de carácter cultural, social y sanitario, a entidades sin ánimo de lucro o con estructuras más democráticas y distributivas, yendo más allá de la reserva existente en legislaciones anteriores dirigida a empresas de inserción y centros especiales de empleo. A través del análisis jurídico de la normativa estatal reguladora de varios tipos de entidades de Economía Social, en concreto de cooperativas de trabajo, sociedades laborales y asociaciones, este estudio demuestra que los requisitos exigidos a los licitadores que deseen concursar en los contratos reservados a través de la Disposición Adicional 48ª de la Ley 9/2017, de 8 de noviembre, de Contratos del Sector Público, son cumplidos por estas y, por consiguiente, debería de facilitarse su participación en este tipo de procesos.
A ação mímica: princípios e poéticas da mímica corporal dramática de Étienne Decroux
Authors: Mascarenhas George
Published: December 2022

O que é mímica corporal dramática? Quais os seus princípios e fundamentos técnicos? Qual a sua aplicabilidade em projetos artísticos contemporâneos? Para discutir essas e outras questões, o livro apresenta alguns aspectos históricos, técnicos e poéticos dessa arte e aborda as controvertidas afirmações acerca das restrições de sua aplicação na contemporaneidade. A obra pretende fornecer um guia de estudos prático-teóricos para os interessados na Mímica Corporal Dramática de Étienne Decroux, como elemento complementar à prática nas salas de ensaio e no exercício cotidiano de artistas da cena.
Metagenomics analysis of the effects of Agaricus bisporus mycelia on microbial diversity and CAZymes in compost
Authors: Chang Wanqiu , Feng Weilin , Yang Yang , Shen Yingyue , Song Tingting , Li Yu , Cai Weiming
Published: December 2022

Agaricus bisporus growth alters the lignocellulosic composition and structure of compost. However, it is difficult to differentiate the enzyme activities of A. bisporus mycelia from the wider microbial community owing to the complication of completely speareting the mycelia from compost cultures. Macrogenomics analysis was employed in this study to examine the fermentation substrate of A. bisporus before and after mycelial growth, and the molecular mechanism of substrate utilization by A. bisporus mycelia was elucidated from the perspective of microbial communities and CAZymes in the substrate. The results showed that the relative abundance of A. bisporus mycelia increased by 77.57-fold after mycelial colonization, the laccase content was significantly increased and the lignin content was significantly decreased. Analysis of the CAZymes showed that AA10 family was extremely differentiated. Laccase-producing strains associated with AA10 family were mostly bacteria belonging to Thermobifida and Thermostaphylospora, suggesting that these bacteria may play a synergistic role in lignin decomposition along with A. bisporus mycelia. These findings provide preliminary evidence for the molecular mechanism of compost utilization by A. bisporus mycelia and offer a reference for the development and utilization of strains related to lignocellulose degradation.
Avionics Architecture Design for Military Unmanned Aerial Vehicles
Authors: Shim Jae Ick , Choi Jae Won , Kim Yong Tae , Yoo Dong Wan , Yang Kook Bo , Ha Hyun Seok , Kim Sang Jin , Lee Seung Yul , Jung Sang Jun
Published: December 2022

This paper describes the design of the avionics architecture for military unmanned aerial vehicles considering the airworthiness requirements for the first time. This design considers the redundancy in the system data bus and the power system and the data link system to meet the system safety requirements of the airworthiness requirements of military UAVs. This avionics architecture design has been verified through the system integration test and the flight test after manufacturing the UAV.
Association Between Metastatic Melanoma Response to Checkpoint Inhibitor Therapy and Tumor-Infiltrating Lymphocyte Classification on Primary Cutaneous Melanoma Biopsies
Authors: Stephens Michael R. , Aderbigbe Oyinade , Xu Wei , Karakousis Giorgos C. , Ming Michael E. , Chu Emily Y.
Published: December 2022

This cohort study examines the association between tumor-infiltrating lymphocyte classification and disease progression among patients with metastatic primary cutaneous melanoma receiving checkpoint inhibitor therapy.
Intensively Pruritic Annular Papules on the Extremities of a Middle-aged Woman
Authors: Wang Yanan , Zeng Yueping
Published: December 2022

A woman in her 50s presented with a 3-month history of intensively pruritic papules rapidly spreading on her extremities. What is your diagnosis?
Characteristics and Treatment Rate of Patients With Hepatitis C Virus Infection in the Direct-Acting Antiviral Era and During the COVID-19 Pandemic in the United States
Authors: Nguyen Vy H. , Kam Leslie , Yeo Yee Hui , Huang Daniel Q. , Henry Linda , Cheung Ramsey , Nguyen Mindie H.
Published: December 2022

Importance

Clinical data on hepatitis C virus (HCV) treatment rates in the United States are sparse.

Objective

To evaluate HCV treatment rates in the era of direct-acting antivirals (DAAs).

Design, Setting, and Participants

This retrospective cohort study used data from the deidentified Optum Cliniformatics Data Mart Database (2014-2021) on patients with HCV in the DAA and COVID-19 eras. The database includes patients with private health insurance in the US.

Main Outcomes and Measures

The treatment rate and changes over time were assessed with adjusted log-binomial regression, and factors associated with treatment were examined using multivariable logistic regression.

Results

A total of 133 348 patients with HCV (79 567 [59.7%] men; mean [SD] age, 59.7 [12.3] years; 4448 [3.3%] Asian, 24 662 [18.5%] Black, and 74 750 [56.1%] White individuals) were included; 38 180 (26.8%) had HCV RNA data, and of those, 20 277 (53.1%) had positive HCV RNA. Overall, 13 214 patients with positive HCV RNA tests (65.2%) received DAA treatment; 6456 of 6634 patients treated with DAAs (97.3%) achieved sustained virologic response. After adjusting for age, sex, and race and ethnicity, the treatment rate in 2018 was 0.5 times greater than the rate in 2014 (adjusted prevalence ratio, 1.50; 95% CI, 1.42-1.59) but declined after 2018, decreasing from 64.8% to 61.2%, and especially after 2019, when it decreased to less than 60% (P < .001). The number of patients with viremic HCV identified in between April 2020 and March 2021 also decreased to 496 from 2761 and 3258 in the preceding 2 years. Receiving care from a gastroenterologist or infectious disease specialist with advanced care practitioner (ie, nurse practitioner, physician assistant, or clinical nurse specialist) was independently associated with greater odds of DAA treatment (adjusted odds ratio [aOR], 1.64; 95% CI, 1.07-1.50). Patients with decompensated cirrhosis and/or hepatocellular carcinoma (HCC) were 31% less likely to receive treatment compared with those without (aOR, 0.69; 95% CI, 0.54-0.90).

Conclusions and Relevance

In this cohort study, less than two-thirds of insured patients with viremic HCV received DAA treatment, with declines in both the treatment rate and the number of viremic HCV diagnoses since 2019 and especially during the COVID-19 pandemic. Further efforts are needed to increase HCV diagnosis and treatment, especially for those with cirrhosis and HCC. An urgent call for nationwide actions to improve access to DAA treatment, community outreach programs, and specialists through referral pipelines is needed in the United States to stay on track to meet the World Health Organization goal of reducing the burden of viral hepatitis with the eventual goal to eliminate viral hepatitis.
Psychedelic Drug Legislative Reform and Legalization in the US
Authors: Siegel Joshua S. , Daily James E. , Perry Demetrius A. , Nicol Ginger E.
Published: December 2022

Importance

Psychedelic drugs are becoming accessible in the US through a patchwork of state legislative reforms. This shift necessitates consensus on treatment models, education and guidance for health care professionals, and planning for implementation and regulation.

Objective

To assess trends in psychedelics legislative reform and legalization in the US to provide guidance to health care professionals, policy makers, and the public.

Evidence Review

Data were compiled from legislative databases (BillTrack50, LexisNexis, and Ballotpedia) from January 1, 2019, to September 28, 2022. Legislation was identified by searching for terms related to psychedelics (eg, psilocybin, MDMA, peyote, mescaline, ibogaine, LSD, ayahuasca, and DMT). Bills were coded by an attorney along 2 axes: which psychedelic drugs would be affected and in what ways (eg, decriminalization, funding for medical research, and right to try). To explore drivers and rates of legislative reform, data were compared with other state indices including 2020 presidential voting margins and marijuana legislative reform.

Findings

Twenty-five states have considered 74 bills (69 legislative initiatives, 5 ballot measures); 10 bills were enacted, and 32 were still active. The number of psychedelic reform bills introduced during each calendar year increased steadily from 5 in 2019 to 6 in 2020, 27 in 2021, and 36 in 2022. Nearly all bills specified psilocybin (67 [90%]), and many also included MDMA (3,4-methylenedioxy-methamphetamine; 27 [36%]). While bills varied in their framework, most (43 [58%]) proposed decriminalization, of which few delineated medical oversight (10 of 43 [23%]) or training and/or licensure requirements (15 of 43 [35%]). In general, bills contained less regulatory guidance than the enacted Oregon Measure 109. While early legislative efforts occurred in liberal states, the margin between liberal and conservative states has decreased over time (although the difference was not significant), suggesting that psychedelic drug reform is becoming a bipartisan issue. In addition, an analytic model based on marijuana legalization projected that a majority of states will legalize psychedelics by 2034 to 2037.

Conclusions and Relevance

Legislative reform for psychedelic drugs has been proceeding in a rapid, patchwork fashion in the US. Further consideration should be given to key health care issues such as establishing (1) standards for drugs procured outside the medical establishment, (2) licensure criteria for prescribers and therapists, (3) clinical and billing infrastructure, (4) potential contraindications, and (5) use in special populations like youths, older adults, and pregnant individuals.
Brain proteome‐wide association study linking‐genes in multiple sclerosis pathogenesis
Authors: Jia Tingting , Ma Yanni , Qin Fengqin , Han Feng , Zhang Chengcheng
Published: December 2022

Objectives

To identify genes that confer MS risk via the alteration of cis‐regulated protein abundance and verify their aberrant expression in human brain.

Methods

Utilizing a two‐stage proteome‐wide association study (PWAS) design, MS GWAS data (N = 41,505) was respectively integrated with two distinct human brain proteomes from the dorsolateral prefrontal cortex, including ROSMAP (N = 376) in the discovery stage and Banner (N = 152) in the confirmation stage. In the following, Bayesian colocalization analysis was conducted for GWAS and protein quantitative trait loci signals to prioritize candidate genes. Differential expression analysis was then used to verify the dysregulation of risk genes in white matter and gray matter for evidence at the transcription level.

Results

A total of 51 genes whose protein abundance had association with the MS risk were identified, of which 18 genes overlapped in the discovery and confirmation PWAS. Bayesian colocalization indicated six causal genes with genetic risk variants for the MS risk. The differential expression analysis of SHMT1 (PFDR = 4.82 × 10−2), FAM120B (PFDR = 8.13 × 10−4) in white matter and ICA1L (PFDR = 3.44 × 10−2) in gray matter confirmed the dysregulation at the transcription level. Further investigation of expression found SHMT1 significantly up‐regulated in white matter lesion, and FAM120B up‐regulated in both white matter lesion and normal appearing white matter. ICA1L was down‐regulated in both gray matter lesion and normal appearing gray matter.

Interpretation

Dysregulation of SHMT1, FAM120B and ICA1L may confer MS risk. Our findings shed new light on the pathogenesis of MS and prioritized promising targets for future therapy research.