bluuebunny/crossref_metadata_2025 huggingface dataset:
Prediction of Structure Activity Relationship (SAR) of Lactobacillus plantarum DA2 content for Cholesterol Reduction Treatment
Authors: Abdullah Dessy , Poddar Sandeep , Purnama Dewi Nadia , Teti Vani Ade
Published: February 2024

Cholesterol is a chemical that is naturally created by the liver but can also be present in animal-based meals like meat and milk. Cholesterol is required by the body for the formation of healthy cells, the production of several hormones, and the production of vitamin D. Although cholesterol is necessary for the body, high levels can be harmful to one's health, hence therapy to lower cholesterol levels using natural products or the aid of bacterial metabolism is required. Lactobacillus plantarum 2DA is a lactic acid bacterium that has potential as a probiotic, so further analysis is needed on its ability as a therapy to reduce cholesterol through a bioinformatics approach. The method used in this research is to search for bacterial secondary metabolites by studying literature from published journals. Each compound is then searched in the PubChem database for its canonical structure and isomeric SMILE (simplified molecular-input line-entry system) and secondary metabolites in bacteria from the literature study were analyzed for potential using WAY2DRUG PASS prediction (http://www.pharmaexpert. ru/passonline/predict.php) as a cholesterol-lowering treatment. The results of the study based on the prediction of the SAR Way2 Drug Pass Server seen in the Probability To Be Active (Pa) values obtained 0.45, 0.49 and 0.37 for anti-hypercholesterolemic, cholesterol antagonist and cholesterol oxidase inhibitors. From the results obtained, it can be recommended that Lactobacillus plantarum 2DA can be further researched in vivo for cholesterol-lowering therapy.
Pengaruh Variasi Waktu dan Kecepatan Pengadukan Terhadap Difusivitas dan Konstanta Reaksi Dengan Proses Ekstraksi Reaktif
Authors: Az Zahra Clarisa Hany , Mustikaningrum Mega , Sawali Fikrah Dian Indrawati , Mustika Pra Cipta Buana Wahyu
Published: February 2024

The world is experiencing a crisis of scarcity of diesel fuel sources. The B30 program is to develop energy sources by utilizing alternative energy sources to prevent petroleum shortages. This program also supports research, namely making biodiesel using non-edible raw materials. Apart from that, another benefit of this research is to determine the effect of time on the yield of biodiesel production, knowing the effect of stirring speed on the diffusivity constant and reaction speed constant of the reactive extraction process. Biodiesel production in this research uses a reactive extraction process. The raw materials used are mahogany seeds, the solvent is methanol, chloroform as a co-solvent, and KOH as a catalyst. This process uses a temperature of 65°C, reaction time of 40 and 80 minutes, and varying stirring speeds of 200 and 300 rpm. The effect of time with a variable stirring speed of 200 rpm the longer the resulting yield increases, while at a stirring speed of 300 rpm the resulting yield decreases. The yield obtained at 200 rpm stirring was 82.363% (40 minutes), 87.6366% (80 minutes), 84.7605% (40 minutes), and 78.7204 (80 minutes). For the methyl ester diffusion constant, the stirring speed of 200 rpm is 8,20 x 10-8 dm2/minute, while the stirring speed of 300 rpm is 8,17 x 10-8 dm2/minute. The reaction rate constant is 1.99 dm3/mol min.
Pengaruh Pre-Treatment Kimia dan Biologi Terhadap Produksi Biogas dari Kulit Kopi
Authors: Nury Dennis Farina , Luthfi Muhammad Zulfikar , Farohi Ahmad Rifqiyan , Widjaja Tri
Published: February 2024

Coffee, as a major commodity in Indonesia, produces a huge number of byproducts and residues during the processing process. Coffee wastes and byproducts produced during coffee berry processing are a major source of contamination and represent significant environmental challenges in the coffee production process. One promising alternative in utilizing coffee wastes is converting into energy source i.e, of biogas from coffee pulp. Coffee pulp has toxic components that act as a methane inhibitor; these type of biomass have a problem with the lignin degradation process, which binds cellulose and hemicellulose. The use of cow's rumen fluid for methane production from coffee pulp is still rare, particularly for rumen fluid. Chemical pretreatment was carried out using alkali-peroxide followed by rumen fluid pretreatment. The performance of biogas produced from coffee pulp (with and without pretreatment) using rumen fluid as an inoculum has been investigated. Biogas was produced in a semi-batch reactor with a working volume of 2 liters for 30 days. Removal lignin, SS, VFA, and biogas yield were measured. This study aims to determine the biogas production from coffee pulp using variation HRT 20 and 30 days. It can be concluded that chemical pretreatment of NaOH - H2O2 combination can reduce lignin up to 75.02%. The volume of biogas produced increased with chemical pretreatment and rumen fluid as compared to the substrate with only rumen pretreatment According to Gas Chromatography analysis, the methane gas obtained from chemical pretreatment and rumen with HRT 30 days is 47.93%, while the methane obtained from rumen pretreatment with HRT 30 days is 34.28%.
Advancing Hardware Security: A Review and Novel Design of Configurable Arbiter PUF with DCM-Induced Metastability for Enhanced Resource Efficiency and Unpredictability
Authors: Preetisudha Meher Lukram Dhanachandra Singh,
Published: February 2024

As the Internet of Things (IoT) and Blockchain technologies continue to assert their dominance in the technical landscape, the demand to enhance security measures becomes foremost. In this context, Physical Unclonable Functions (PUFs) are widely used hardware security primitives that can be used to solve a wide range of security issues. To support hardware security solutions, this paper presents an extensive overview and analysis of the existing Physical Unclonable Functions (PUFs) used as True Random Number Generators (TRNGs). Recognizing the shortcomings of current PUF designs, we propose a configurable Arbiter PUF design employing Digital Clock Manager (DCM)-induced metastability as an entropy source, presenting a robust solution for evolving hardware security. To mitigate the adverse consequences of metastability, the proposed Arbiter PUF includes a Carry Chain primitive with four Flip-Flop clones. Acknowledging the constantly evolving IoT and Blockchain environment, the suggested configurable Arbiter PUF is made to satisfy the highest security standards. By exploiting the inherent variations in FPGA technology, we aim to reduce system resource and area consumption, aligning with the efficiency criteria of modern applications. The system's performance is additionally enhanced by an on-chip post-processing based on DSP. Simulation results demonstrate successful implementation on a Xilinx Basys-3 FPGA board, offering a scalable and efficient solution. The generated sequences of the proposed PUF undergo rigorous testing, including National Institute of Standards and Technology (NIST) statistical tests for uniqueness, reliability, and randomness.  This holistic approach aims to improve the PUF's performance and security.
Kanser Tedavisinde Bakteri Destekli İlaç Taşıyıcı Sistemler
Authors: ÖZTÜRK Maide , BOZDAĞ PEHLİVAN Sibel
Published: February 2024

Kanser tedavisine yönelik terapötiklerin ve tedavi yaklaşımlarının geliştirilmesine rağmen hastalık dünya çapında önde gelen ölüm nedenlerinden biridir. Spesifite eksikliği, sitotoksisite ve çoklu ilaç direnci gibi sınırlamalar nedeniyle kemoterapi, radyasyon terapisi ve immünoterapi gibi kanser tedavileri ile henüz istenen düzeyde başarı elde edilememiştir. Bu nedenle yan etkilerin azaltılarak etkin bir tedavinin gerçekleştirilebilmesi için hedefe yönelik tedavilerin geliştirilmesi büyük önem taşımaktadır. Ancak kanser mikroçevresi, vaskülarizasyonu ve hipoksik bölgeleri ile hedeflendirme için birçok fizyolojik engele sahiptir. 1800’lü yıllardan günümüze kadar yapılan araştırmalar, bakterilerin bu fizyolojik engelleri aşarak kanser dokusuna seçici olduğunu göstermiştir. Bakterilerin doğal olarak tümör dokularını hedefleme ve dokuda birikme özelliklerine sahip olduğunun keşfedilmesiyle birlikte araştırmacılar, bakteri destekli ilaç taşıyıcı sistemler üzerine yoğunlaşmıştır. Bakterilerin hareketlilik, immün yanıt oluşturma ve kolay modifikasyon özelliğiyle konvansiyonel ilaç taşıyıcı sistemlerden daha üstün olduğu bildirilmiştir. Bu derlemede kanser tedavisine yönelik bakteri destekli ilaç taşıyıcı sistemler konusunda literatürde yer alan en güncel gelişmeler değerlendirilmiştir.
Recent Examples of eVTOL Aeroacoustics
Authors: Barakos George
Published: February 2024

This seminar presents recent work carried out at the CFD Laboratory of Glasgow on eVTOL. The seminar will present a method for eVTOL rotor blade optimisation based on harmonic balance CFD, and demonstrate its use. Examples from aeroacoustics computations will them be given covering propeller and prop-rotor noise.
Understanding complex materials using advanced electron microscopy
Authors: Kübel Christian
Published: February 2024

Electron microscopy has seen tremendous developments over the last couple years providing unprecedented possibilities in materials characterization at the nanometer and atomic scale. With the high spatial resolution and high beam currents available in aberration corrected (S)TEM, highly sensitive detectors for imaging and spectroscopy and fast readout speeds, new microscopy methods have been established, which enable advanced insights into materials, their 2D/3D structure and chemistry as well as some of their functional properties.
With this presentation, I want to provide an overview of the techniques and illustrate the information that can be obtained by transmission electron microscopy. Examples will include atomic resolution imaging and spectroscopy and different 4D-STEM approaches to understand structure and properties (electric, magnetic or mechanical) of oxide-based quantum materials, advanced aluminium alloys and metallic glasses.
La situación actual del derecho de filiación en España
Authors: Barber Cárcamo Roncesvalles
Published: February 2024

Este trabajo aborda el análisis de las cuestiones más pujantes del Derecho de filiación español en la actualidad, atendiendo a las últimas contribuciones doctrinales, la más reciente jurisprudencia y la reforma legislativa llevada a cabo por la reciente Ley 4/2023, de 28 de febrero, para la igualdad real y efectiva de las personas trans. Para ello, da cuenta breve de los antecedentes legislativos y sobre todo jurisprudenciales que explican la situación actual, ilustrativa del cambio vivido en las concepciones sociales. Para terminar, ofrece propuestas para la futura e inaplazable reforma legislativa del Derecho de filiación.
Sentencias, año 2022
Authors: Méndez Tomás Rosa
Published: February 2024

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Un imprevisto tra capo e collo: la sindrome di Lemierre
Authors: Gibellato Elisabetta , Petrela Sigi , Arosio Andrea , Peccatori Nicolò , Melzi Maria Luisa , Lazzerotti Alessandra , Biondi Andrea
Published: February 2024

A healthy 15-year-old boy was hospitalized due to the persistence of lateral cervical swelling associated with fever and worsening of headache. He underwent a neck and facial mass CT scan showing a thrombophlebitis of the internal jugular vein extended to the intracranial sinuses. The diagnosis of Lemierre syndrome (LS) was formalized with positive blood colture for Fusobacterium necrophorum. Intravenous antibiotic therapy associated with anticoagulant therapy was started with complete clinical recovery after 4 weeks of treatment. A close clinical-instrumental follow-up was set up. Lemierre syndrome is a thrombophlebitis of the internal jugular vein, that in this case was extended to the intracranial sinuses. It is a rare condition, secondary to the extension of an infectious process starting from the oropharynx. The clinical picture is characterized by high fever, persistent pharyngitis followed by sepsis, pneumo-nia or atypical laterocervical pain. Fusobacterium necrophorum, a gram-negative anaerobe bacteriu,, is the responsible pathogen in most of the cases (>90%). The antibiotic treatment is prolonged (at least 4-6 weeks); occasionally a parallel surgical approach is necessary. The start of anticoagulant thera-py for internal venous thrombosis associated with LS is still matter of debate.
Sintomi neurologici da causa insolita
Authors: Fiorenza Gianmarco , De Luca Lorenzo , Donnarumma Bernadette , Tranchese Sonia , Rezzuto Martina , Mosca Caterina , Ponte Giuliana , Liguori Laura , Acampora Emma , Tarallo Luigi
Published: February 2024

The case of a drowsy and tachycardic infant eventually diagnosed with cannabis intoxication is presented.
Un vomito insidioso
Authors: Tranchese Sonia , Fiorenza Gianmarco , Donnarumma Bernadette , De Luca Lorenzo , Coppola Daniela , Occhiati Luisa , Ponte Giuliana , Ciccarelli Gian Paolo , Acampora Emma , Tarallo luigi
Published: February 2024

The authors describe the case of a 7-year-old boy presenting with morning vomiting eventually diagnosed as idiopathic epilepsy of childhood.
Menometrorragia come causa di anemia grave
Authors: D'Agostin Martina
Published: February 2024

A diagnosis of anaemia due to menometrorrhagia was eventually made in an 11-year-old severely anaemic girl.
Specificity of Motor Contributions to Auditory Statistical Learning
Authors: Boeve Sam , Möttönen Riikka , Smalle Eleonore H.M.
Published: February 2024

Statistical learning is the ability to extract patterned information from continuous sensory signals. Recent evidence suggests that auditory-motor mechanisms play an important role in auditory statistical learning from speech signals. The question remains whether auditory-motor mechanisms support such learning generally or in a domain-specific manner. In Experiment 1, we tested the specificity of motor processes contributing to learning patterns from speech sequences. Participants either whispered or clapped their hands while listening to structured speech. In Experiment 2, we focused on auditory specificity, testing whether whispering equally affects learning patterns from speech and non-speech sequences. Finally, in Experiment 3, we examined whether learning patterns from speech and non-speech sequences are correlated. Whispering had a stronger effect than clapping on learning patterns from speech sequences in Experiment 1. Moreover, whispering impaired statistical learning more strongly from speech than non-speech sequences in Experiment 2. Interestingly, while participants in the non-speech tasks spontaneously synchronized their motor movements with the auditory stream more than participants in the speech tasks, the effect of the motor movements on learning was stronger in the speech domain. Finally, no correlation between speech and non-speech learning was observed. Overall, our findings support the idea that learning statistical patterns from speech versus non-speech relies on segregated mechanisms, and that the speech motor system contributes to auditory statistical learning in a highly specific manner.
Analisis Kualitatif Dan Kuantitatif Dokumen Rekam Medis Rawat Inap Sectio Caesarea: Literature Review
Authors: Resta Dwi Yuliani
Published: February 2024

Based on the 2018 Riskesdas data, it is stated that delivery is by means of action cesarean sectionreached 17.6%. This event is considered to exceed the standards set by WHO. The purpose of this study was to analyze qualitative and quantitative inpatient medical record documents cesarean section with review literature. The results of this study were based on a qualitative analysis of medical record documents on the 4 articles that were conductedreviews, based on qualitative analysis seen from a review of the completeness and consistency of diagnoses,reviews completeness and consistency of diagnostic records, reviews recording during care and treatment,reviews exists informed consent there are still many medical record documents that are not complete and consistent, one of the factors that influence this incompleteness is the level of awareness of health service workers who lack the importance of completing patient medical record documents. Meanwhile, based on quantitative analysis, from the 4 articles inreviewsthere is only 1 article that states its completeness reaches 100%. Reviews identification of incompleteness on the sex item, reviews authentication is found in the nurse's signature and full name, doctor's name and signature, reviewsreporting of incomplete filling in filling out the main and entry diagnoses and not attaching the results of laboratory examinations, where as on reviews records are in illegible writing in the case of doctors' and nurses' writings that are unclear or illegible, corrections in writing strokes that are not signed.

 

Keywords: qualitative analysis, quantitative analysis, sectio caesarea.
Gambaran Kecerdasan Emosional Dengan Gaya Manajemen Konflik Perawat
Authors: Pohan Novi Hanjani , Putri Dwi Helga  , Stevani J. Sinuhaji  , Cristin E. Manurung  , Rika Endah Nurhidayah
Published: February 2024

Conflict is a complex process that cannot be avoided. Conflict needs to be managed positively so that it has a good impact on the development of individuals and organizations. Conflict management is very important in solving problems in the workplace, especially for nurses. Conflict management has a close relationship with the emotional intelligence of nurses in building and maintaining cooperation in order to produce the desired resolution.

The purpose of this study was to determine the description of emotional intelligence with the conflict management style of nurses. The method used is a search for management style journals in nursing conflict with nurses' emotional intelligence, including designs, studies, samples, and research results of journals that are searched. The journals collected are the latest published journals and have been selected through Google Scholar, an international journal indexed by Sinta.

The results of the study show that there is a relationship between emotional intelligence and nurses' conflict management. Conflict and its management are motivated by many factors, therefore it is important to properly assess the influencing factors that are expected to have an impact on the conflict management approach used by nurses. So that nurses with high emotional intelligence are able to resolve conflicts and choose a good conflict management style.

Keywords : Inteligent emotional, style management, nurse’s conflict management
Penggunaan Metode Evaluasi Sistem Informasi Kesehatan di Indonesia: Literature Review
Authors: Chotimah Siti Noor , Nurvita Silvia , Natalia Dewi Viny
Published: February 2024

Evaluasi sistem dalam suatu Sistem Informasi Kesehatan (SIK) menjadi suatu proses untuk meminimalisir kesalahan informasi yang dihasilkan serta mengukur kepuasan pengguna. Evaluasi sistem dilakukan untuk maintenance di masa mendatang. Saat ini banyak metode yang dapat digunakan untuk melakukan evaluasi sistem, termasuk SIK. Kajian pustaka terkait metode evaluasi SIK telah banyak dilakukan. Penelitian ini bertujuan untuk mengetahui metode-metode evaluasi SIK yang diterapkan pada fasilitas pelayanan kesehatan di Indonesia. Jenis metode evaluasi SIK yang menjadi pembahasan dalam penelitian ini adalah metode Technology of Acceptance Model (TAM), End User Computing Satisfaction (EUCS), Task Technology Fit (TTF), dan Human Organizational Technology (HOT) Fit Model. Berdasarkan hasil penelitian, didapatkan pemilihan metode evaluasi bergantung dari sudut pandang evaluasi yang dilakukan. Sudut pandang tersebut diantaranya penekanan terhadap kepuasan pengguna, penerimaan pengguna, manusia (user), organisasi dan teknologi yang digunakan. Secara keseluruhan metode yang digunakan dalam penelitian dapat melakukan evaluasi. Perlu adanya pertimbangan sudut pandang pengguna sistem untuk hasil evaluasi sistem yang lebih baik di masa mendatang.
Nanomedicine for the Treatment of Lungs Cancer Its Challenges and Future Perspective-A Review
Authors: Hussain Izaz , Umam Abdul Hadi , Borah Lakhyajit , Papi Dakme , Nath Digbijoy , Bordoloi Tapoban , Gogoi Himanshu , Hoque Mohibul , Kalita Nihalini
Published: February 2024

A major public health concern with a global reach,lungs cancer necessitates cutting-edge techniques to treatment. Nanomedicine is a new technology that is currently being used to treat and diagnose lung cancer. This review examines the difficulties in using nano medicine to treat lung cancer and shows the promising directions for this rapidly developing field of study. The issues raised in this review cover a wide range of topics, such as medication delivery, targeted precision, toxicity, and legal obstacles. Approaches based on nanomedicine have the potential to get through these barriers thanks to improvements in drug delivery to lung cancer cell, a decrease in side effects, and increased therapeutic effectiveness. Additionally, this study explores the potential applications of nanomedicine for the treatment of lung cancer, highlighting the significance of cutting-edge technology including personalized medicine techniques,theranostic nanosystems, and targeted nanoparticles. These developments carry the possibility of individualized treatment plans, improved therapeutic results, and reduced side effects. Nanomedicine offers a multifaceted approach to address the challenges of lung cancer treatment, bringing new hope to patients and clinicians alike. By overcoming existing limitations and harnessing the potential of emerging technologies, nano medicine is poised to play a pivotal role in the future of lung cancer therapy. This review serves as a comprehensive overview of the field, shedding light on the path forward in the fight against lung cancer.
Gastro politika: politik bir araç olarak yemek
Authors: Üner Emir Hilmi
Published: February 2024

Ortak bir toplumsal ve kültürel değer olması nedeniyle yemek, tarih boyunca siyasi otoriteler tarafından çeşitli amaçlar doğrultusunda politik bir araç olarak kullanılmıştır. Yemeğin ortak bir kültürel değer olarak birleştirici gücü, toplumsal bütünlüğün sağlanmasında önemli bir işleve sahiptir. Yemek, toplumsal ve ulusal birliğin sağlanması için birleştirici bir unsur olabildiği gibi sınıflar arasındaki sınır ve farklılıkları koruyan ve vurgulayan ayrıştırıcı bir unsur olarak da karşımıza çıkmaktadır. Yemek aynı zamanda sembolik bir dil ve bir “yumuşak güç” olarak uluslararası ilişkilerde de büyük bir öneme sahiptir. Yemeğin bölgesel, ulusal ve uluslararası düzeyde bir kamu politikası aracı olarak kullanılması günümüzde “gastro politika” kavramıyla ifade edilmektedir. Gastro politika, özellikle 21. yüzyıldan itibaren hem kamu politikası uygulayıcıları hem de bu alanda çalışan akademisyenler için son derece önemli bir kavram haline gelmiştir. Bu dönemde gerçekleştirilen başarılı gastro politika örnekleri incelendiğinde ulusal ve uluslararası düzeyde önemli kazanımlar elde edildiği görülmektedir. Günümüz dünyasını büyük ölçüde şekillendiren küreselleşme, dijital devrim, savaş ve göç gibi gelişmeler neticesinde önemli gastro politika araçları olan gastro milliyetçilik ve gastro diplomasi, ulusal ve uluslararası düzeyde önemli politika araçları haline gelmiştir. Bu çalışmanın temel amacı gastro politika kavramının ve önemli tarihsel ve güncel gastro politika örneklerinin literatür taraması yöntemiyle incelenmesidir. Araştırmada ayrıca gastro diplomasi ve gastro milliyetçilik kavramları da ele alınmıştır.
NAVIGATING CHALLENGES IN ARABIC PEDAGOGY: INTERROGATING THE ROLE OF SCIENCE AND TECHNOLOGY
Authors: Aminullahi A. R.
Published: February 2024

Arabic plays a crucial role on the global stage, being deemed indispensable. Within the United Nations, three languages are officially recognised: Arabic, French, and English. However, unlike its counterparts, Arabic receives limited support from the Nigerian government. Despite being a subject offered at both Junior and Senior Secondary School levels, the approach to teaching Arabic needs enhancement to captivate and stimulate the learners' interest. This study delves into the traditional methods employed by Arabic teachers in the past, which have inadvertently discouraged students from selecting Arabic for their professional development. The paper explores how incorporating science and technology can serve as a remedy to make Arabic more appealing and interesting to students. Furthermore, the introduction of new ideas, innovations, techniques, and scientific and technological instructional materials is considered to be a potential solution for effective teaching and learning of Arabic literature
The Role of the Church in Low-Income Housing in Namibia
Authors: Khiba Ritta , Ntlhe Daphne
Published: February 2024

The paper examines the church's role in Namibia's low-income housing process. The study followed the qualitative method; data were drawn from journals, books, newspapers, and other relevant material. The article argues that the church in Namibia plays a positive role in low-income housing and promotes Sustainable Development Goals. The findings reveal that the church established a foundation for the current Shack Dwellers Federation of Namibia, an umbrella body of savings groups that address housing issues for low-income groups. The church plays a significant role by building houses for the poor, donating materials, and helping low-income communities alleviate poverty. The study supports participatory planning efforts in housing, highlighting that the church and faith-based organizations have a place in promoting Sustainable Development Goals, particularly goals 1, 2, and 11. It augments literature in religious studies, the built environment, and sustainable urban development by investigating the church's role in housing provision. In contrast, most studies focus on the church’s involvement in politics, culture, and socio-economic development. The study will benefit stakeholders who want to contribute towards goal 11 (Sustainable cities and communities). Additionally, the contribution will grow as the research serves as a novel contemporary reference for future studies in the same field.
Study of the replacement of the small aggregate by saw powder in sustainable concrete
Authors: De Carvalho Otávio Anacleto Mizael , Santos Gustavo Soares , de Matos Antônio Claret , Mendes Lourival Marin , Marotta Luiza Ignez Mollica , Clemente Guilherme Augusto Bertelli Fernandes , Lima Gilberto de Miranda
Published: February 2024

Nowadays, the construction industry has been thinking more and more about sustainability, seeking to make the technologies offered nowadays walk along with practices that have the least impact on the environment. The main purpose of this project was to evaluate the replacement of the small aggregate (sand) by the saw dust in a sustainable concrete. In this line of reasoning, cylindrical concrete proof bodies were carried out with different levels of substitution of the aggregate, 5%, 10%, 15% and 20%, in an attempt to analyze the effects caused by the sawdust on the properties of the concrete, and, in addition, to verify the new results of resistance of the concrete with substitution of the sand. The results of the compression resistance tests showed that concrete shafts with aggregate substitution content of 15% and 20% did not meet the requirements of NBR 8953 (ABNT, 2015), which considers a characteristic compressive strength of at least 20 MPa for concrete for structural purposes. With regard to workability, the results showed that besides conventional concrete, only the substitution traits of 5% and 10% showed good numbers, once again the other traits did not obtain the expected results for structural concrete. The results show that the smaller the substitution of the small aggregate by the sawdust is, the greater the resistance to the compression of the concrete. The same goes for the workability of concrete.
Sustainable rural development supported by beekeeping in Fernades Pinheiro, Paraná
Authors: Costa Jéssica , Mussio Carla Fernanda , Rickli Milayne Lopes , Ruiz Emilio Carlos Zilli , Garret Alexandre Techy de Almeida , Grespan Tiago , Nauiack Carlos Henrique Boscardin
Published: February 2024

The Association of Beekeepers and Meliponiculturists of Fernandes Pinheiro was founded on May 1, 2007, with the initial objective of uniting family farmers and local beekeeping and meliponiculture enthusiasts through associations. In addition to obtaining income through honey production, AMFEPI was concerned with the dissemination of bee species, aiming to repopulate the region, due to existing concerns about the extinction of bees and the resulting environmental consequences. Therefore, the aim of this manuscript is to analyze the process of gradual change and incorporation of the Beekeeping activity in the rural areas of the municipality of Fernandes Pinheiro, Paraná. During a period of ten years, Association of Beekeepers and Meliponicultors of Fernandes Pinheiro (AMFEPI) acted on several fronts promoting the incorporation of this activity, thus diversifying the income of the associated families. The beekeeping activity is based on the three pillars of sustainability: economic because it generates income, social because it uses family labor, involving mainly young people and women in the activity, and ecological because it depends on the maintenance and conservation of natural forests. The Central-South region of Paraná, where the municipality of Fernandes Pinheiro is located, has a vocation for the development of beekeeping activities, where the market in bee products is expanding. Herein we demonstrate that through the incorporation of beekeeping activities on their properties, family farmers associated with AMFEPI were able to diversify their income and, consequently, obtain an improvement in their living conditions, generating profit and innovation with socio-environmental concerns, indicating that beekeeping, in addition to Being a sustainable agricultural activity can bring income to the producer.
Teaching the Virtue of Kindness through Using Art Works
Authors: Sansom Dennis L.
Published: February 2024

Art works provide a unique and influential way to teach human virtues because they can place individuals (or particular artistic expressions) within the ambiguities, complexities, and forces of the human experience. I use four art works to teach about the virtue of kindness: Giotto di Bondonie's Scene 2: St. Francis Giving His Mantle to a Poor Man; Bishop Charles Francois in Victor Hugo's Les Misérables; Adam in William Shakespeare's As You Like It; and Sonya in Fyodor Dostoevsky's Crime and Punishment. In these four examples, we see necessary characteristics of being a kind person: supererogatory behavior, altruistic behavior, a display of the way the world ought to be, and the presence of a kind soul.
Living in the Moment is for Oysters
Authors: Sher George
Published: February 2024

The idea that we should simply live in the moment, and should not concern ourselves about the future or the past, has long been a staple of popular philosophy. In this paper, I first attempt to clarify the doctrine and then examine the case for accepting it. My conclusions are, first, that a number of its implications seem quite unpalatable; second, that the main advantages that living in the moment are said to yield are greatly overstated; and, third, that to live by any version of the doctrine that was not highly watered down would be to sacrifice much of what gives meaning to our lives.
“Quanto dovea parergli il dubio buono”: On Doubt, Fidelity Tests, and the Marriage Plot in Ariosto's Orlando furioso
Authors: Hicks-Bartlett Alani
Published: February 2024

In Ludovico Ariosto's Orlando furioso, the foundational marriage of Bradamante and Ruggiero is the crucial climax to which the entire epic directs itself, yet the text's management of the couple's union and preparation for their nuptials is highly ambiguous. More than extolling the strength and success of the marriage that grounds the dynastic union, the Furioso highlights instead numerous examples of amorous infidelity that insist upon the precarity of faith-based relationships. The emphasis given to the problematic fragility of spousal trust and the attendant failures of proof and “knowledge” illustrate the difficulties of believing the words and promises of others, for instance, which frequently creates an epistemological impasse or crisis for the individual who yearns—often vainly—for absolute certainty and unbreakable faith. Likewise, the concept of marital fidelity itself is also continually doubted, challenged, and essayed throughout the entire Furioso, as various episodes involving fidelity tests demonstrate. By examining fraught authorial assurances to bring readers to the successful union that begins the Este line alongside key fidelity tests that occur in the text prior to the momentous foundational marriage, this article explores the connection between the impediments that hinder the Estense union and Ariosto's scathing authorial commentary on the fragility of all faith-based relationships.
Nuove forme di associazionismo italiano in Brasile: un'indagine stilistica e linguistica in comunità online post Covid-19
Authors: Ferroni Roberta
Published: February 2024

Lo studio indaga nuove forme di aggregazione virtuale da parte di emigrati italiani vecchi e nuovi iscritti a due gruppi Facebook. Il corpus è costituito da scambi (neo)epistolari, prodotti nella fase post Covid-19, da italiani che risiedono in Brasile o che stanno progettando un trasferimento e con profili differenziati (nuclei familiari, studenti e ricercatori universitari, piccoli imprenditori, pensionati, turisti). L'analisi qualitativa ha permesso di analizzare le varietà linguistiche migratorie in uso nei due gruppi Facebook e con esse gli scopi e i valori che intendono veicolare.
PREDICTORS AND OUTCOMES OF NEONATAL SEPSIS IN TERTIARY CARE SETTING: A RETROSPECTIVE STUDY
Authors: ALI F , ADIL H , MANZOOR U , AZIZ N , IQBAL M
Published: February 2024

Neonatal sepsis represents a critical challenge in healthcare, particularly in tertiary care settings. A comprehensive understanding of the predictors and consequences is pivotal for enhancing clinical practice and patient outcomes. A retrospective study was conducted on a sample size of 120 neonates to explore the predictors and outcomes of neonatal sepsis. The analysis encompassed a wide range of variables, including maternal characteristics (e.g., age, religion, education), obstetric factors (e.g., PROM, UTI/STI history), neonatal demographics (e.g., age, sex, birth weight), healthcare facilities (e.g., place of delivery, length of stay), and clinical care parameters (e.g., invasive procedures, mode of delivery). Multivariate logistic regression was employed to identify relationships between these factors and sepsis outcomes. Maternal and obstetric factors showed significant correlations with neonatal sepsis. Neonatal characteristics revealed a mean age of 3.1 days, equal gender distribution, and a mean birth weight of 2.6 kg. Health facility indicators pointed to balanced utilization and transport means. Clinical care variables illustrated a balance in delivery modes and attendance. The logistic regression model (Nagelkerke R²: 0.52) identified specific coefficients indicating relationships between variables and sepsis. The mortality rate among neonates with sepsis was 27.8%, with an average stay of 15 days and 38.9% complications rate. The study provides valuable insights into the multifaceted nature of neonatal sepsis, emphasizing the importance of maternal and clinical care factors. The results underscore the necessity for early identification, targeted interventions, and comprehensive care strategies to reduce the incidence and adverse outcomes of neonatal sepsis in tertiary care settings.
THE IMPACT OF LIP FORM ON THE PERCEPTION OF THE IDEAL INCISAL DISPLAY AT REST
Authors: MUNAWAR MI , EJAZ M , YASEEN AZ , SHAH SA
Published: February 2024

The perception of an aesthetically pleasing smile involves a multitude of factors, among which the shape and form of the lips play a pivotal role. Understanding how lip morphology influences the perception of an ideal incisal display during rest is crucial in the realm of cosmetic dentistry and facial aesthetics. The basic aim of the study is to find the impact of lip form on the perception of the ideal incisal display at rest. A total of 214 participants were enrolled in this observational study, meeting the inclusion criteria of being 18 years or older and representing diverse racial backgrounds. Exclusion criteria comprised individuals with oral health conditions impacting lip posture, recent dental procedures influencing incisal display, and cognitive impairments hindering compliance with instructions. Demographic information, including age, gender, and racial background, was recorded for each participant. Incisal display measurements were obtained and documented by trained evaluators following established procedures to minimize potential bias or variations in assessments. Thirty-six modified images simulating varied levels of maxillary incisal shown across three distinct lip forms—straight, moderate, and high—were created from the initial photographs of 214 volunteers. The mean incisal show for the linear lip form was hypothetically calculated as 1.5 mm (SD = 0.3), 2.3 mm (SD = 0.4) for the moderate lip form, and 3.0 mm (SD = 0.5) for the high lip form. Statistical comparison using ANOVA revealed significant differences in mean incisal display among lip form categories (F(2,105) = 80.72, p < 0.001). It is concluded that there is a strong association between lip form, cultural influences, and preferences for incisal display, highlighting the intricate role of individual perceptions in shaping dental aesthetic preferences. This inclination towards varied incisal displays appears to resonate across both dental professionals and laypersons, remaining consistent irrespective of gender.
Histopathological and Immunological Effects of Nebivolol 5% Topical Cream in Mice Model of Imiquimod-Induced Psoriasis
Authors: Mahdi Zainab Azal , Hussain Anwer Mahmood , Alblesh Hasan Adnan
Published: February 2024

Background: Psoriasis is a chronic inflammatory skin condition that affects multiple systems. Topical therapy is one of the most important modalities in the treatment of this disease, and efforts are directed toward developing more effective topical therapies. Objective: To investigate the possible anti-psoriatic effect of Nebivolol 5% topical cream in mice based on observational, histopathological, and biochemical outcomes. Methods: Forty-five male Swiss Albino mice were divided into five groups; each group contained nine mice with shaved dorsal skin. Group I remained as the control group while the rest of the groups were induced psoriasis by Imiquimod (IMQ) for six consecutive days and underwent different interventions for each group for eight consecutive days, including administering Nebivolol 5% topical cream. The clinical, pathological and laboratory effects were then measured. Results: Topical nebivolol significantly reduced the inflammatory signs of the psoriatic lesions, and these findings were supported by the histopathological examination. Topical Nebivolol also significantly decreased IL-17 levels, as well as Tumor Necrosis Factor-alpha (TNF-α) levels and Vascular Endothelial Growth Factor (VEGF) levels, in comparison with the non-treated Imiquimod-induced psoriatic mice group. Conclusions: Nebivolol has a comparable anti-psoriatic effect to the effect of clobetasol due to its anti-inflammatory and antioxidant effects. It could be a promising future treatment for psoriasis as an alternative to steroids.
A Qualitative Study on E-Sports Players’ Leadership Perceptions Regarding Their Team Coaches
Authors: Keçeci Orçun , Çelik Veli Onur
Published: February 2024

Having emerged following the professionalization of digital gaming, e-sports has created its ecosystem and become a large-scale industry itself. Teams involved in this industry experience a social environment just like in other organizational structures. As e-sports is a relatively newer branch when compared to other sports branches, leadership in e-sports is not a commonly studied topic in the literature. Therefore, the aim of this study is to explore leadership perceptions of e-sports players in a comprehensive way. A team coach is often considered the leader in e-sports. The study was designed according to the principles of phenomenology, which is a qualitative research method. The semi-structured interview form developed by the researchers was used as the data collection instrument. The interviews were conducted with a group of e-sports players who met the predetermined criteria for participation in the study. The data was analyzed by using the content analysis method. First, the codes were determined, and later, the categories, and finally, the themes were identified out of these categories. Accordingly, it was found that leadership in e-sports is perceived under five themes: physical characteristics, personality traits, professional qualifications, technical skills, and management skills. Finally, it can be concluded that leadership in e-sports is quite similar to leadership in other traditional sports in many ways. However, the study showed that it has unique characteristics that need studying within the framework of the digital age and technological advancements.
Optoelectronic Transimpedance Converter Based on MOS Photovaricap for High Resistive Gas Sensors
Authors: Semerjyan B. O. , Kananov D. A. , Alexanyan M. S.
Published: February 2024

The gas detectors consist of two parts: metal-oxides gas sensor and transducer. The sensing material is made of a thin semiconductor layer. The transducer is responsible for converting the change in the several physical parameters of the thin sensitive layer into a measurable signal. Due to the high output resistance of high resistive gas sensors and the low input currents of amplifiers, electrometric cascades are employed, followed by the conversion of the gas sensors small direct current into an active current signal using a mechanical modulator (dynamic capacitor) to enhance sensitivity and stability. The aim of this research is to analyze the main characteristics of a novel type of dynamic capacitor that utilizes a surface metal-oxide-semiconductor (MOS) photovaricap (PV) as the regulating element when detecting signals from high resistive gas sensors. For the creation of surface MOS PVs, samples of p-Si with varying resistivity were chosen. A thin layer of SiO2 was deposited on these samples, onto which a translucent metallic electrode was applied. Modulation of the PV capacitance was achieved by illuminating it with a gallium arsenide LED. As a result, the capacitance of the PV is changed, producing a variable voltage across the load resistor, which was then amplified and recorded. It was observed that the settling time of the useful signal is determined by two factors. The first is the RC chain composed of the load resistance of the gas sensor and the input capacitance of the PV, and the second is slow relaxation phenomena in the structure of the MOS PV that lead to the screening of the induced charge. Characteristics of the MOS PV as a dynamic capacitor and the features of the photo capacitance as a semiconductor element, in turn, determine the transimpedance conversion coefficient. The conducted research showed that MOS PVs can be applied to register small DC currents and voltages from high resistive gas sensors. In this case, ordinary narrowband or wideband amplifiers with relatively low input resistance can be used instead of electrometric amplifiers with mechanical dynamic capacitors. The considered circuit has been experimentally tested with commercial resistors.
Nurturing, learning, and collaboration in medical education: An exploration of the Jigsaw teaching method
Authors: S Archana , Bahuleyan Biju , V Shilpa , K Sreeja , Babu Rose , Thomas Neenu , Davis Aruna , Shojan Tereesa
Published: February 2024

Background: Jigsaw is a cooperative teaching strategy used in education that promotes collaboration and group learning among students.

Aims and Objectives: The aim of the study was to assess the knowledge level of students following the Jigsaw teaching method and to analyze the student’s perspective regarding its design and implementation.

Materials and Methods: A cross-sectional study was conducted in 100 phase one MBBS students in October 2023. The students were randomly divided into 20 core groups with five students each and a case scenario with five sub-questions was shared. Then, each sub question was assigned to a member, and they were regrouped to form expert groups where the students interacted and discussed the respective sub topics. Later, the participants were back in the core groups where they applied their knowledge for peer teaching. Knowledge assessment both before and after the activity was done to determine the effectiveness of the method. Student perception survey was used to evaluate the design, implementation, and effectiveness of the Jigsaw teaching method in Physiology.

Results: The mean post-test scores were significantly higher than the mean pre-test scores (6.94 ± 1.84 vs. 4.75 ± 1.71, P < 0.001). About 94% of students agreed that Jigsaw teaching method provided better understanding of the topic and 95% of students opinionated that this was helpful in developing communication skills, positive peer relation, and leadership qualities.

Conclusion: Jigsaw is an effective teaching method which encourages active participation and teamwork among students to provide deeper understanding of the subject.
Fusiform “True” Posterior Communicating Artery Aneurysm with Basilar Artery Occlusion: A Case Report
Authors: Shah Ritu , Saraf Rashmi
Published: February 2024

Isolated posterior communicating artery (PCoA) aneurysms are rare, predominantly fusiform in morphology, and rarely present with subarachnoid hemorrhage. Endovascular management of this pathology is technically challenging due to extreme tortuosity, the artery course in the subarachnoid space, sharp angulations at PCoA junctions with the parent artery, and, at times, associations with either internal carotid artery or basilar artery occlusions. We present a case of a ruptured fusiform PCoA at the junction of middle and distal third with concomitant proximal basilar artery occlusion. The PCoA reforms the posterior circulation, making it a vital artery. Stent-assisted coiling was performed with extreme difficulty in achieving distal positioning of the stents in the basilar artery/posterior cerebral artery/distal PCoA due to artery tortuosity. There was technical difficulty in the stent deployment. After changing strategies to a larger diameter laser-cut stent, endovascular treatment could be performed. There were good angiographic and clinical outcomes with stable occlusion at 6-month-follow-up.
PRODUCTION ARRANGEMENTS FOR TEMPORARY AND PERMANENT CROPS IN THE MUNICIPALITIES OF SANTARÉM AND MOJUÍ DOS CAMPOS - PARÁ
Authors: Meira Hélio Sandre dos Anjos , Ramos Raimundo Sátiro dos Santos
Published: February 2024

In the northern region of Brazil, the municipalities of Santarém and Mojuí dos Campos have been experimenting with the transformation of a productive system formerly based on traditional family agriculture to large scale mechanized agriculture. A new agricultural frontier has established itself in the region, driven by favorable conditions of climate, topography, and low land cost, and since then has attracted an increasing number of grain farmers from various regions of the country. Thus, the objective of this article is to analyze the dynamics of the permanent and temporary crop production chains in the municipalities of Santarém and Mojuí dos Campos, in the western region of the state of Pará, as well as identify the main factors that interfere in this productive chain. For this purpose, quantitative data were collected from the IBGE System of Automatic Recovery (Sidra) and the information was collected in the database of Municipal Agricultural Production (PAM). We concluded with the present research that grain productivity in Santarém and Mojuí dos Campos shows itself to be growing in recent years due to the high prices of soybeans and corn in the international market.