bluuebunny/crossref_metadata_2025 huggingface dataset:
A rapid tick exposure test for monitoring acaricide resistance in Rhipicephalus sanguineus sensu lato ticks on dogs
Authors: Jongejan Frans , Berger Laura , Papadopoulos Elias , Reck José , Ferreira Priscila Teixeira , Scott Fabio Barbour , de Avelar Barbara Rauta , Guimarães Brena Gava , Correia Thais Ribeiro , Hulsebos Iris , Petersen Alita , Klafke Guilherme
Published: September 2024

Background

Brown dog ticks (Rhipicephalus sanguineus sensu lato) are vectors of pathogens adversely affecting the health of dogs in many regions of the world. The three-host life cycle of R. sanguineus s.l., with all stages feeding on dogs, can lead to an uncontrolled build-up of large tick populations if not controlled by acaricides. However, frequent tick control on dogs using acaricides has led to the emergence of resistance to permethrin and fipronil. Currently, the larval packet test (LPT) is the standard tick resistance test, which is laborious, requires laboratory facilities, and takes at least 6 weeks before larvae derived from engorged female ticks can be tested. Our novel approach is to expose semi-engorged adult ticks to acaricides immediately after removing them from dogs, obtaining results within 24 h.

Methods

Adult ticks from three laboratory colonies of R. sanguineus s.l. were tested in RaTexT®, a rapid tick exposure test in which ticks were confined to small compartments and exposed to an acaricide-impregnated, specially designed matrix. Resistance was confirmed by testing larvae derived from the same laboratory colonies using the LPT. RaTexT® was also used to determine the susceptibility of R. sanguineus acaricides in dog shelters.

Results

RaTexT® detected resistance to permethrin in adult R. sanguineus s.l. ticks from two Brazilian laboratory colonies compared to a susceptible laboratory strain originating in Greece. Resistance was confirmed by LPT testing of larvae from the same colonies with resistance factors between 2.2 and 3.1. All laboratory strains were susceptible to fipronil. A suspected case of fipronil resistance at a dog shelter in Caxias do Sul, Brazil, was resolved within 24 h by testing adult ticks in RaTexT® and could be attributed to improper treatment.

Conclusions

RaTexT® is a valuable tool for monitoring the development of resistance to synthetic pyrethroids or phenylpyrazoles in tick-infested dogs.

Graphical Abstract
Methotrexate-induced leukoencephalopathy presenting as acute-onset limb weakness in a child: a case report
Authors: Pathiraja Hashan , de Abrew Gayathri , de Silva Linushika , Fernando Sanjaya , Randeny Shobhavi , Mettananda Sachith
Published: September 2024

Background

Methotrexate is an essential medicine used to treat childhood malignancies including acute lymphoblastic leukemia. Neurotoxicity manifesting as leukoencephalopathy is an important adverse effect of methotrexate. Methotrexate-induced leukoencephalopathy classically demonstrates sub-acute-onset neurological manifestations that include learning disability, progressive dementia, drowsiness, seizures, ataxia, and hemiparesis. These are rare in children and are generally reported following intrathecal or intravenous use of methotrexate. In contrast, acute onset neurotoxicity with oral use of methotrexate is very rare. We report a 10-year-old boy presenting with acute onset limb weakness and neurological signs due to methotrexate-induced leukoencephalopathy following oral methotrexate.

Case presentation

A 10-year-old Sri Lankan boy presented with fever and headache for 5 days and difficulty in walking for 2 days. He was unable to stand unaided on admission, and his parents complained of repetitive, involuntary extension movements involving the right upper limb. He is a child diagnosed with acute lymphoblastic leukemia who was on treatment for a relapse with daily oral dexamethasone and mercaptopurine, weekly oral methotrexate and folinic acid, and once every two weeks intrathecal vincristine.

On examination, he had dystonic movements of the right upper limb and hypotonia and reduced muscle power (grade 3/5) of the left upper and lower limbs proximally and distally. The muscle power of the right side was grade 4 (out of 5). Tendon reflexes were diminished in all four limbs, and the plantar response was flexor bilaterally. The child had dysmetria and intension tremors on both sides.

T2-weighted magnetic resonance imaging of the brain revealed symmetrical high signal intensities with diffusion restriction involving bilateral putamen, subcortical areas, and deep white matter, suggesting treatment-related neurotoxicity due to methotrexate-induced leukoencephalopathy. Oral methotrexate was discontinued. He showed gradual improvement in limb weakness and other neurological signs following treatment with intravenous folinic acid, aminophylline, dexamethasone, and oral dextromethorphan.

Conclusion

This case report describes a patient with rapidly progressing methotrexate-induced leukoencephalopathy following oral methotrexate. It highlights that the risk of neurotoxicity persists even with the oral use of methotrexate; therefore, the prescribers should be vigilant of this uncommon side effect.
Metagenomic analyses of a consortium for the bioremediation of hydrocarbons polluted soils
Authors: Pandolfo Emiliana , Durán-Wendt David , Martínez-Cuesta Ruben , Montoya Mónica , Carrera-Ruiz Laura , Vazquez-Arias David , Blanco-Romero Esther , Garrido-Sanz Daniel , Redondo-Nieto Miguel , Martin Marta , Rivilla Rafael
Published: September 2024

A bacterial consortium was isolated from a soil in Noblejas (Toledo, Spain) with a long history of mixed hydrocarbons pollution, by enrichment cultivation. Serial cultures of hydrocarbons polluted soil samples were grown in a minimal medium using diesel (1 mL/L) as the sole carbon and energy source. The bacterial composition of the Noblejas Consortium (NC) was determined by sequencing 16S rRNA gene amplicon libraries. The consortium contained around 50 amplicon sequence variants (ASVs) and the major populations belonged to the genera Pseudomonas, Enterobacter, Delftia, Stenotrophomonas, Achromobacter, Acinetobacter, Novosphingobium, Allorhizobium-Neorhizobium-Rhizobium, Ochrobactrum and Luteibacter. All other genera were below 1%. Metagenomic analysis of NC has shown a high abundance of genes encoding enzymes implicated in aliphatic and (poly) aromatic hydrocarbons degradation, and almost all pathways for hydrocarbon degradation are represented. Metagenomic analysis has also allowed the construction of metagenome assembled genomes (MAGs) for the major players of NC. Metatranscriptomic analysis has shown that several of the ASVs are implicated in hydrocarbon degradation, being Pseudomonas, Acinetobacter and Delftia the most active populations.
How control and eradication of BVDV at farm level influences the occurrence of calf diseases and antimicrobial usage during the first six months of calf rearing
Authors: Dobos Attila , Dobos Vilmos , Kiss István
Published: September 2024

Background

Bovine viral diarrhoea (BVD) is one of the major cattle diseases causing economic losses worldwide. Nowadays the disease manifests mainly as virus-induced immunosuppression and early embryonic death, impacting overall herd performance and contributing to increased antibiotic usage in calf rearing.

Methods

In our study we investigated the effect of rapid BVDV control measures on calf diseases and antimicrobial usage after weaning on a large industrial dairy farm. Persistently infected (PI) animals were identified and removed from the herd within a short period of time, and all susceptible animals were vaccinated against BVDV. Recorded herd parameters and AB usage were monitored retrospectively and compared with data collected after starting the BVD control program.

Results and discussion

The programme began in January 2023 with identifying and eliminating PI animals from the farm. Twenty-one PI animals were found by using RT-qPCR testing of blood sera out of the 1571 animals tested (1.33%). Subsequent testing (January and December 2023) identified further 28 PI animals amongst the 542 calves tested shortly after birth, and all were instantly removed from the farm. In parallel with the BVDV eradication measures, AB usage dropped by more than 50% compared to previous years. Calf mortality also decreased from 7.45 to 4.38% as the control program progressed. Correspondingly, both the number of respiratory and diarrhoea cases decreased dramatically on the farm while the eradication measures were in place.

Conclusion

Our study clearly demonstrated the positive effects of BVDV eradication on the improvement of calf health and importantly, a reduction of AB usage, contributing to the One Health perspective of farm animal production.
Effectiveness of interventions for informal caregivers of people with end-stage chronic illness: a systematic review
Authors: McGuigan K. , Laurente G. , Christie A. , Carswell C. , Moran C. , Yaqoob M. M. , Bolton S. , Mullan R. , Rej S. , Gilbert P. , McKeaveney C. , McVeigh C. , Tierney C. , Reid J. , Walsh I. , Forbes T. , Noble H.
Published: September 2024

Background

People living with advanced, non-malignant chronic conditions often have extensive and complex care needs. Informal or family caregivers often provide the care and support needed by those with advanced chronic conditions at home. These informal caregivers experience many challenges associated with their caring role, which can impact their own wellbeing. Whilst there is growing evidence around the impact on carers, guidance on support for informal caregivers of patients with advanced, non-malignant, chronic conditions is lacking, with little evidence available on effective psychosocial carer interventions. This systematic review explored existing interventions for caregivers of those with advanced, non-malignant, chronic illness, in order to assess the effectiveness of these interventions in improving psychosocial outcomes.

Methods

Electronic databases, Medline, CINAHL, EMBASE, and PsycINFO, were searched up to the end of March 2023. Studies meeting the inclusion criteria, focusing on interventions to improve psychosocial outcomes, such as depression, anxiety, quality of life, and caregiver burden, in this cohort of caregivers were included. Data were extracted regarding study setting, design, methods, intervention components, and outcomes. Risk of bias and quality assessment were conducted.

Results

A total of 5281 articles were screened, ultimately identifying 12 studies for inclusion, reported in 13 publications. A narrative synthesis revealed mixed results. Psychosocial interventions resulted in more significant improvements in psychosocial outcomes than psychoeducational or support interventions, with interventions for carer-patient dyads also reflecting more positive outcomes for caregivers. Evidence-based interventions, guided by an appropriate theoretical model, were reportedly more effective in improving caregiver outcomes. Differences in outcomes were related to intervention development, design, delivery, and outcome assessment.

Conclusions

This review, to our knowledge, is the first to explore the effectiveness of interventions in improving psychosocial outcomes for caregivers of those with advanced, non-malignant, chronic conditions. The review highlights the need for more robust, sufficiently powered, high-quality trials of evidence-based interventions for caregivers of people with advanced chronic illness. Optimal intervention duration and frequency of sessions are unclear and need further exploration.
Experiences and perceptions of patients with cancer receiving home-based chemotherapy: a qualitative systematic review protocol
Authors: Witwaranukool Porawan , Phonyiam Ratchanok , Wu Yanni , Kynoch kathryn
Published: September 2024

Background

Home-based chemotherapy (HBC) has emerged as a standard option for treating various types of cancer, primarily to decrease the waiting time for treatment. As HBC gains more recognition, ongoing research is delving into the experiences of patients with cancer who receive chemotherapy in a home setting or chemotherapy closer to home. Understanding these experiences is vital for the use of chemotherapy delivery outside the traditional hospital environments. This review aims to synthesize and critically appraise qualitative studies that investigate the experience and perspectives of patients with cancer who received parenteral chemotherapy administration in home settings. Findings will be used to develop evidence-based policies to support home-based care models.

Methods

This review will follow JBI methods for systematic reviews of qualitative evidence. The databases for searching will include MEDLINE (PubMed), CINAHL (EBSCOhost), PsycINFO (EBSCOhost), ProQuest Health and Medical Collection, two Chinese databases, CNKI and Wanfang, and one Thai database, ThaiJO. Studies published in English, Chinese, and Thai will be considered for inclusion. Two reviewers will independently undertake study selection, data extraction, and critical appraisal of the methodological quality of studies. The synthesized findings will be assessed using the ConQual approach.

Discussion

The synthesis of qualitative studies on this topic will provide insights into the nuanced and varied experiences of patients receiving chemotherapy within the comfort of their homes. The review will also provide evidence-based recommendations to policymakers and healthcare administrators, to support the implementation of HBC for patients.

Systematic review registration

Systematic review registration: PROSPERO CRD42024500476.
Temporal dynamics of leaf area index and land surface temperature correlation using Sentinel-2 and Landsat OLI data
Authors: Ahmed Ali Yasin , Ali Abebe Mohammed , Ahmed Nurhussen
Published: September 2024

Background

Understanding the complex relationship between vegetation dynamics and land surface temperature (LST) is crucial for comprehending ecosystem functioning, climate change impacts, and sustainable land management. Hence, this study conducts a temporal analysis of leaf area index (LAI) and LST data derived from Sentinel-2 and Landsat Operational Land Imagery (OLI) in the Mille River Basin, a tropical region in Ethiopia. LAI data were generated using Sentinel-2 imagery processed with the Sentinel Application Platform (SNAP) toolbox, an open-access earth observation analysis tool, while Landsat OLI collection 2 level 2 data were utilized for precise LST retrieval. The Mann–Kendall test was used to detect trends in the time series data.

Results

The trends in the mean LAI were statistically significant at P values of 0.05 and 0.10 for the annual and seasonal trends, respectively. The mean LST trends were insignificant throughout the study period except for the summer season, for which the P value was 0.07. The correlation between the LAI and LST was weak (R2 = 0.36) during the crop-growing seasons (summer and spring) but moderate in winter (R2 = 0.46) and autumn (R2 = 0.41).

Conclusion

The findings of this research clarify the complex relationships between variations in surface temperature and vegetation growth patterns, providing insight into the environmental mechanisms driving the dynamics of localized ecosystems. The study underscores the implications of these findings for informed decision-making in sustainable land management, biodiversity conservation, and climate change mitigation strategies.
Zero-crosstalk silicon photonic refractive index sensor with subwavelength gratings
Authors: Ahmed Syed Z. , Hasan Mehedi , Kim Kyungtae , Kim Sangsik
Published: September 2024

Silicon photonic index sensors have received significant attention for label-free bio and gas-sensing applications, offering cost-effective and scalable solutions. Here, we introduce an ultra-compact silicon photonic refractive index sensor that leverages zero-crosstalk singularity responses enabled by subwavelength gratings. The subwavelength gratings are precisely engineered to achieve an anisotropic perturbation-led zero-crosstalk, resulting in a single transmission dip singularity in the spectrum that is independent of device length. The sensor is optimized for the transverse magnetic mode operation, where the subwavelength gratings are arranged perpendicular to the propagation direction to support a leaky-like mode and maximize the evanescent field interaction with the analyte space. Experimental results demonstrate a high wavelength sensitivity of − 410 nm/RIU and an intensity sensitivity of 395 dB/RIU, with a compact device footprint of approximately 82.8 μm2. Distinct from other resonant and interferometric sensors, our approach provides an FSR-free single-dip spectral response on a small device footprint, overcoming common challenges faced by traditional sensors, such as signal/phase ambiguity, sensitivity fading, limited detection range, and the necessity for large device footprints. This makes our sensor ideal for simplified intensity interrogation. The proposed sensor holds promise for a range of on-chip refractive index sensing applications, from gas to biochemical detection, representing a significant step towards efficient and miniaturized photonic sensing solutions.

Graphical Abstract
Repurposing metabolic regulators: antidiabetic drugs as anticancer agents
Authors: Dhas Yogita , Biswas Nupur , M.R. Divyalakshmi , Jones Lawrence D. , Ashili Shashaanka
Published: September 2024

Drug repurposing in cancer taps into the capabilities of existing drugs, initially designed for other ailments, as potential cancer treatments. It offers several advantages over traditional drug discovery, including reduced costs, reduced development timelines, and a lower risk of adverse effects. However, not all drug classes align seamlessly with a patient's condition or long-term usage. Hence, repurposing of chronically used drugs presents a more attractive option. On the other hand, metabolic reprogramming being an important hallmark of cancer paves the metabolic regulators as possible cancer therapeutics. This review emphasizes the importance and offers current insights into the repurposing of antidiabetic drugs, including metformin, sulfonylureas, sodium-glucose cotransporter 2 (SGLT2) inhibitors, dipeptidyl peptidase 4 (DPP-4) inhibitors, glucagon-like peptide-1 receptor agonists (GLP-1RAs), thiazolidinediones (TZD), and α-glucosidase inhibitors, against various types of cancers. Antidiabetic drugs, regulating metabolic pathways have gained considerable attention in cancer research. The literature reveals a complex relationship between antidiabetic drugs and cancer risk. Among the antidiabetic drugs, metformin may possess anti-cancer properties, potentially reducing cancer cell proliferation, inducing apoptosis, and enhancing cancer cell sensitivity to chemotherapy. However, other antidiabetic drugs have revealed heterogeneous responses. Sulfonylureas and TZDs have not demonstrated consistent anti-cancer activity, while SGLT2 inhibitors and DPP-4 inhibitors have shown some potential benefits. GLP-1RAs have raised concerns due to possible associations with an increased risk of certain cancers. This review highlights that further research is warranted to elucidate the mechanisms underlying the potential anti-cancer effects of these drugs and to establish their efficacy and safety in clinical settings.
Effect of CLX training adjunct to PNF and conventional physiotherapy on pain and balance in patients with chronic lower back pain: A randomised clinical trial protocol
Authors: Tikhile Priya , Patil Deepali
Published: September 2024

Lower back pain that has lasted longer than 12 weeks is referred to as chronic lower back pain (CLBP). Lumbar extensor deterioration is a typical characteristic of CLBP. Muscular degeneration could impact proprioception along with reducing strength and endurance, which would further exacerbate concerns about balance. Along with force-matching ability, lower back muscles working together is frequently compromised in CLBP patients. The prime goals of bodily workout in administration of long-lasting lower back ache are advance muscular strength and flexibility, to re-establish injured tissues and to contribute easy engaging in daily tasks. Proprioceptive sense is reduced in CLBP patients due to mechanical alterations in their musculature. Hence, in order to develop an efficient management plan, it is crucial for patients and physiotherapists to understand the alterations that result from the shift in trunk muscular endurance in people with CLBP and how they impact the functional level. Outlined here is a proposed study aiming to evaluate the effectiveness of consecutive loop TheraBand (CLX) adjunct to proprioceptive neuromuscular facilitation (PNF) and conventional physiotherapy exercises on subjects with CLBP in a two-arm parallel superiority randomized clinical trial in reducing pain and enhancing balance. The participants will be split into two groups for equal allocation, after which the intervention CLX adjunct to PNF will be provided to one group and conventional physiotherapy exercises will be provided for another group for six weeks, a total of six days a week, for 50 minutes per day. After six weeks of intervention, the results will be assessed for pain and balance. The implementation of this physiotherapy technique in treatment could occur if the study’s hypothesis is successful in CLBP. Additionally, it will aid in lowering the incapacity in activities of daily living in those recovering from lower back pain.

CTRI registration number: CTRI/2023/05/052851
Methods of a Sixteenth-Century Actor-Director: Lope de Rueda’s Performance-Based Approach to Adaptation
Authors: Thomas Alex J. H.
Published: September 2024

Abstract: Despite the derivative plotlines, crude characterizations, and prioritization of performance over posterity for which scholars have criticized his Cuatro comedias , Lope de Rueda (1505?–65?) received great acclaim among contemporaries. To reconcile this disconnect between abiding popular acclaim in the late sixteenth century and critical dismissals in literary histories, this article draws new attention to his practices as actor-director, where Rueda was the impresario at the helm of a successful itinerant troupe. In particular, analysis here illuminates one key artistic practice, proposing that the structural changes made to Rueda’s Italian sources reveal methods that enabled consistently popular performances. By examining Rueda’s Medora (adapted from Gigio Artemio Giancarli’s La zingana ) and Los engañados (from the Accademici Intronati di Siena’s Gl’Ingannati ), I argue that Rueda consciously simplified imbroglios and handed control of plotlines to the servants for whose portrayal he was famed. His plays, then, were crafted to enable his direction of temporary cast members onstage during performance. A comparison of these adaptations with one intended for amateurs, the Comedia de Sepúlveda (from Girolamo Parabosco’s Il Viluppo ), reveals such changes to be specific to the professional actor-director.
Marvelous Dualities in Juan Ruiz de Alarcón’s El semejante a sí mismo
Authors: Estrada José
Published: September 2024

Abstract: An examination of the layered, dual meanings of the term maravilla in El semejante a sí mismo shows the hand of Juan Ruiz de Alarcón navigating his own criollo identity. The double meanings of maravilla reflect a conflict between the inclination to adopt the dominant views and rhetoric of the Spanish Empire and the counterbalancing impulse to undermine this colonial agenda. This article observes this tension in two examples. The first is the discourse of the “Desagüe de Huehuetoca,” a marvel of engineering designed to regulate water flow in Mexico City, which I interpret as a kind of cabinet of wonders. The second source of strain emerges from the disguise assumed by the protagonist of El semejante a sí mismo , which I examine in metatheatrical terms. Another reflection of the overarching tension between validating and resisting imperialism comes to light in the way Ruiz de Alarcón, describing wonders of the world, contends with the literary legacy of his formidable predecessor, adapting and reframing key motifs from Lope de Vega’s La octava maravilla , which celebrated the building of the Escorial palace, likening it to a biblical wonder, the Temple of Salomon.
El gran teatro del mundo de Calderón de la Barca: Ortodoxia y textos prohibidos
Authors: Matzkevich Hernán
Published: September 2024

Abstract: This article examines the connections of El gran teatro del mundo with heterodox intellectual traditions that the Spanish Inquisition targeted for scrutiny or censorship. While many critics have considered El gran teatro del mundo a prominent example of Calderón de la Barca’s Catholic orthodoxy, this study ponders discursive elements that link the auto sacramental to Neoplatonic natural philosophy. Indeed, this work reveals elements that connect it to the intellectual world associated with early modern natural philosophy, such as its implicit conception of matter ( magia naturalis ), the divinization of space, and the anthropomorphization of the world. Close scrutiny of Calderón de la Barca’s drama reveals elements that connect it to Kabbalistic traditions, particularly the anthropomorphization of space which links with the Kabbalistic notion of Adam-Kadmon . Having explored these connections to intellectual currents outside the realm of Catholic orthodoxy, the article concludes by examining textual strategies Calderón de la Barca deployed to allay potential accusations of heresy.
Calderón, Spinoza y los afectos en escena
Authors: Ribes Clara Monzó
Published: September 2024

Abstract: Pedro Calderón de la Barca and the philosopher Baruch Spinoza manifested, each in their own way, that profound interest in the intricacies of the human being that was so characteristic of early modern mentalities. The playwright and philosopher each delved into the exploration of passions and affections, construed as being in constant conflict with reason. These pages analyze the common ties between Spinoza’s Ethics and some of the touchstones of Calderon’s dramatic corpus, including La vida es sueño , El médico de su honra , La dama duende , and El mágico prodigioso. The correspondences between Spinoza and Calderón will help us understand conceptions of emotions in early modernity, whether in scientific inquiry or in literature and theater. In this sense, Calderonian characters present striking examples of complex psyches whose twists and turns are physically translated. Their actions, gestures, and speeches also reveal a relentless pursuit of recognition from a rational point of view.
The Wisdom, Unbound, of Szilvia Szmuk-Tanenbaum: On Collaboration, Comedias Sueltas , and Other Scholarly Enterprises
Authors: Hernández Julia C.
Published: September 2024

Abstract: Szilvia Szmuk-Tanenbaum, lifelong bibliophile and the creator of the Comedias Suelta USA website, welcomed Associate Editor Julia Hernández into her book-filled Upper East Side apartment in New York City. In their conversation, Szmuk-Tanenbaum discussed her journey as a scholar and librarian; her inspiration for developing online bibliographic databases; her service to the Bulletin of the Comediantes as the compiler of its annual bibliography from 1987–2002; and her passion for intergenerational, interdisciplinary scholarly collaborations, through coauthorship of articles and financial support for emerging scholars.
Irrigating Blood: Plato on the Circulatory System, the Cosmos, and Elemental Motion
Authors: C Ampbell Douglas R.
Published: September 2024

abstract: This article concerns the so-called irrigation system in the Timaeus ’s biology (77a–81e), which replenishes our body’s tissues with resources from food delivered as blood. I argue that this system functions mainly by the natural like-to-like motion of the elements and that the circulation of blood is an important case study of Plato’s physics. We are forced to revise the view that the elements attract their like. Instead, similar elements merely tend to coalesce with each other in virtue of their tactile features as the atomists describe. The notion of attraction is replaced with this notion of mere coalescence. I begin by outlining how blood is made from food. I then argue that an understanding of health and disease compels us to read Plato as if he were an atomist and to abandon the popular scholarly interpretations according to which the elements attract each other.
Ockham on the Puzzle of Prophecy and Future Contingency
Authors: Soler César Reigosa
Published: September 2024

abstract: Are these claims compatible: the future is contingent, and yet prophecies reveal the future? William of Ockham argues that they are in Tractatus de praedestinatione (q.1, d.8) and in the Fourth Quodlibet (q.4). But his two solutions to the puzzle of how prophecy and future contingency can be reconciled face significant objections that seem to undermine Ockham’s theory of future contingents. In this paper, I argue that the relevant objections lose their force once Ockham’s views on prophecy are properly understood. In the first part of the paper, I closely examine the puzzle as well as Ockham’s solutions and the objections raised against him. In the second part, I counter the objections while offering an original interpretation of Ockham’s semantics of what I call “prophecies of choice.”
Wolff on Substance, Power, and Force
Authors: Hamid Nabeel
Published: September 2024

abstract: This paper argues that Wolff’s rejection of Leibnizian monads is rooted in a disagreement concerning the general notion of substance. Briefly, whereas Leibniz defines substance in terms of activity, Wolff retains a broadly scholastic and Cartesian conception of substance as that which per se subsists and sustains accidents. One consequence of this difference is that it leads Wolff to interpret Leibniz’s concept of a constantly striving force as denoting a feature of substance separate from its static powers, and not as their replacement. For Wolff, powers are essential possibilities of acting in subjects suited for independent existence. Force is a further ingredient that provides a reason for the contingent operation of powers. Unlike Leibniz, Wolff conceives force narrowly as a principle of actuality, which he calls the “nature” of substance, as distinct from its principle of possibility, or essence.
Ryle’s Debt to Pragmatism and Margaret Macdonald
Authors: Misak Cheryl
Published: September 2024

abstract: In this essay, I argue that Gilbert Ryle’s 1949 The Concept of Mind owes much to the little-known work of Margaret Macdonald. In 1937, Macdonald presented to Ryle her expansion of the pragmatist ideas she found in C. S. Peirce and F. P. Ramsey: (1) beliefs are dispositions; (2) there is a distinction between knowledge how and knowledge that ; and (3) laws are inference tickets or rules with which we meet the future. It is my contention that Ryle drew on, without acknowledgment, Macdonald’s presentation of these pillars of the pragmatist position. This argument will not only bring the superb analytic philosopher Margaret Macdonald back into the light where she belongs, but will also elaborate the important insights of pragmatism about generalizations, hypotheses, and causal laws, all of which remain influential.
Stop the Presses! Publishing Chinese Character Simplification, 1935–1936
Authors: Weng Jeffrey
Published: September 2024

abstract: Simplified Chinese characters ( jiantizi ) were first implemented as official policy under the Nationalist government of the Republic of China in late 1935. Less than four months later, in early 1936, the policy was rescinded. Existing historiography emphasizes the role of conservative political opposition in simplification's demise. However, the practical difficulties of simplification must also be considered. While promulgating simplification, the government also mandated the use of new phonetic annotations ( zhuyin fuhao ) in pedagogical publications. These two simultaneous demands on publishing companies imposed costs that neither the industry nor the government was willing to bear. Based on previously overlooked archival documents, along with examinations of the financial positions of the leading publishing firms and the national budget of China at the time, I argue that simplification's failure should be attributed not only to political opposition but also to the material and economic constraints on the companies responsible for its implementation. 摘要: 1935 年國民政府實施漢字簡化政策，但旋即撤消。歷史學家迄今強調政治力對此政策導致的影響，而忽略物質因素。當時政府要求全國教育出版物需標明注音，致使印刷成本爆增。本文將根據官方檔案和出版業財務數據，論證漢字簡化政策的失敗除因政治因素，經濟面受限為另一主因。
An Oral Reading of the Golden Rule and its Significance for Matthew 7:12
Authors: Draper Jonathan A.
Published: September 2024

Abstract: It has been argued that oral theory can provide “an alternative to the tradition/redaction cul-de-sac” (Botha 2012, xv) but, if so, can texts produced orally be re-oralized? John Miles Foley (1995) has argued that it can, and his theoretical framework and methodology is explored by testing them using the Golden Rule in Matt 7:12 as an exemplar. Using Foley’s determination of the performance arena by careful “triangulation and following the chain of interlocking metonomy” in all the examples of the Golden Rules available to me I read the text of Matthew in this oral register to “key ourselves into the performance arena” through the signals and gaps it provides. The key binary metonym for this particular triangulation is found in “walking two ways” and this in turn relates to the master myth of ‘covenantal nomism’, the entry of Israel into the Land and the terms required by God, namely Torah. The consistent role of the Golden Rule in the oral tradition is that of a Summary of the Torah. The negative form of the Rule is normative, but the positive form found in Matthew presents a new “dialect” found only in the Christian tradition.
Daniel’s Seventy Weeks in Luke 1–2: Allusion or Illusion? Fulfilment or Prefiguration?
Authors: MacPherson Anthony
Published: September 2024

Abstract: In the early 20th century, Eric Burrows (1940) and René Laurentin (1957) made the argument that Luke 1–2 features a 490-day period which is a deliberate allusion to Dan 9’s seventy weeks prophecy. This view has received some support but suffered its most significant pushback when Raymond Brown in 1977 dismissed it in his major work on the infancy narratives of Matthew and Luke. Brown’s criticisms have influenced later commentators (e.g., Bock 1994). This may account for the tentativeness of support, if it is mentioned at all, in contemporary Lucan commentaries. This article will first revisit the earlier view of Burrows and Laurentin and will offer a general defence of their basic position against Brown’s objections. However, limitations and problems in their position are recognised and discussed, and a new modified understanding of Luke’s allusion to Daniel’s seventy weeks will be advanced. It will be argued that Luke is not seeking to indicate that Daniel’s seventy weeks are being fulfilled in the birth of Jesus. Rather, Luke is showing that a complementary 490-day period in the infancy of John and Jesus prefigures their future work, and this parallels Daniel’s seventy-week prophecy. Luke either designs or discerns in the infancy of John and Jesus a miniaturised Daniel-like 490-day period which is also a prefiguration of the future of John and Jesus. The result is that Luke’s 490 days helps prepare the reader for the fulfilment in history of Daniel’s seventy-week prophecy in Luke 3–4.
Shifting the Focus in New Testament Studies: Theatrical Spaces and Spaces for God-Praise Singing Among First-Century Christ Followers
Authors: van der Bank Annelie
Published: September 2024

Abstract: The recent theatrical turn in theology has produced fruitful conversations between drama as art form and theology aimed at present-life living, and now also for historical theological research aimed at enhancing current knowledge of religious practices of the first-century Christ movement. If the twenty-first-century critical spectator focuses on the sounds and not only on the silences that emanate from the distant stage, there are many interesting phenomena to view, such as the various spaces in which Christ-following communities practised their religious singing. The power of God-praise singing is widely recognised, as well as the ambiguities about the practice, because of the scarcity of evidence for the religious singing practices of the first-century Christ followers. One way in which some of the static can be tuned out, is to consider various spaces in which Christ followers performed their faith. Contemporary notions about theatrical spaces are useful to construct common relational structures to connect with the liturgical singing of the ancient Christian communities, because theatrical spaces shape and are shaped by various factors, in the same manner in which the Christ movement shaped and was shaped by its world.
The “Strong” and the “Weak” in Romans 14: 1–15:13 and Covid-19-Related Tensions in Christian Congregations: The Prospects and Perils of Relating Current Concerns to Sacred Scripture
Authors: Stenschke Christoph
Published: September 2024

Abstract: This essay probes whether (and how) deep differences of opinion concerning the Covid-19 pandemic and the governmental measures set in place to fight it can be related to Paul’s instructions in Romans 14:1–15:8 where he refers to severe conflicts within the Roman congregations. The article describes the nature of the controversy in Romans 14–15 and how it relates to the current socio-cultural context of inner-congregational disputes in the wake of the Covid-19 pandemic. This is followed by a discussion of the hermeneutical challenges of relating Romans 14:1–15:13 to some aspects of the Covid-19 pandemic. Further sections relate text and context, address neglected aspects in Romans 14:1–15:13 and the need for additional perspectives. The article discusses in detail the hermeneutical challenges involved in applying this ancient text to the current situation where the contended issues concern not only “opinions” but also established medical facts.
The Encroachment of the Digital: The Novel in 2023
Authors: Cloonan William
Published: September 2024

abstract: This article provides a selective overview of the novel in 2023. In addition, through references to the technical and editorial changes currently affecting Livres Hebdo , France's leading book publishing trade journal, the essay considers ways in which the increasing emphasis given to online publishing is influencing the development of the contemporary business of literature.
The Year in Poetry 2023: Communities
Authors: Julio Maryann De
Published: September 2024

abstract: The year 2023 marked the fortieth anniversary of the Marché de la Poésie, held every June, in Paris, with editors, poets, and readers gathered for readings, book deals, and other activities. Many of the works discussed in this year's article represent communities of poets assembled in person or on the page, from Caribbean poets to poet-translators. Community is a theme in the works that examine the collective aspects of language or the many kinds of poems that unite us, "poèmes-rencontres," as James Sacré puts it in Une fin d'après-midi continuée.
Bloc-notes culturel 2023: Au cœur de l'âge identitaire
Authors: Dalle Matthieu
Published: September 2024

abstract: Année de la contestation et du désordre, 2023 est marquée par le passage dans la douleur de réformes législatives sur les retraites et sur l'immigration et par de violentes émeutes qui, au début de l'été, touchent l'ensemble du pays. Elles font suite à la mort d'un jeune homme d'origine maghrébine tué par un policier lors d'un contrôle routier. Comme l'attestent également les débats sur l'interdiction de l'abaya à l'école et la polarisation des prises de position au sujet du conflit israélo-palestinien, la société française continue d'être parcourue de profondes fractures culturelles et identitaires qui fragilisent le vivre ensemble républicain.
Le sport français : Exploring a New Facet of French Culture
Authors: Sturm Jessica L.
Published: September 2024

abstract: From pick-up games in the park or neighborhood to the fervor that accompanies the FIFA World Cup tournaments, sports are a significant part of modern life. However, sports are not immediately associated with France, despite the country's excellent record of performance in international competitions, not to mention hosting the premier international cycling event and one of four Grand Slam tennis tournaments. I present an intermediate-advanced college-level culture class I created and taught, using sports as a cultural and historical lens into French society and giving students an opportunity to communicate in French about the global phenomenon that is sports. Abstract: Des matchs informels dans les parcs ou dans les quartiers, à la ferveur qui accompagne la Coupe du Monde de la FIFA, le sport est important dans la vie moderne. Néanmoins, on n'associe pas toujours le sport avec la France, en dépit d'excellentes performances françaises dans les compétitions internationales, et qu'elle est l'hôte du Tour de France et du tournoi de Roland-Garros. Je présente un cours universitaire de culture française, niveau intermédiaire/avancé, que j'ai créé et enseigné. Ce cours emploie le sport comme angle culturel et historique de la société française et donne aux étudiants l'occasion de s'exprimer en français au sujet de ce phénomène global.
Le séisme de la sensualité dans l'œuvre de Kettly Mars: De l'aliénation du corps par l'histoire à la sexualité comme menace à la hiérarchie sociale
Authors: Choquet Isabelle
Published: September 2024

abstract: Les corps des personnages de Kettly Mars sont des champs de bataille reflétant les forces en conflit de la société haïtienne. L'héritage colonial qui a engendré une stratification sociale rigide manifeste son emprise sur leur sexualité, ce qui cause des dégâts psychiques et des maux sociaux. Ces œuvres montrent aussi que le corps peut devenir catalyseur de changements quand les personnages revendiquent une autre place que celle que l'histoire et la société leur assignent en imposant leur propre récit pour se définir et se sortir de l'héritage colonial. Abstract: In Kettly Mars' novels, bodies are battlefields reflecting social tensions in Haiti. The colonial legacy has created a rigid social stratification which dictates each person's place depending on their socio-economic milieu. Mars depicts a fragmented society where many characters lose their sexual agency, which provokes psychological disorders. On the other hand, other characters use their bodies to transgress boundaries and claim a place other than the one assigned to them by society. They impose their own narrative to define themselves and free themselves from the colonial legacy. Their sexual agency has the revolutionary potential to threaten social hierarchy.
RF photonic interference mitigation system using silicon nitride ring resonator network
Authors: Marpaung David , Eijkel Maarten , Braamhaar Redlef , van der Slot Peter
Published: September 2024

We experimentally demonstrate a novel RF interference mitigation technique using a network of low-loss silicon nitride ring resonators. The rings are used for complex (phase and amplitude) line-by-line shaping of higher-order sidebands from an electro-optic modulator to discriminate large and small RF signal input, thereby achieving strong (30 dB) mitigation of a large signal and virtually no mitigation for small signals.
Scientometric mapping of the trends, impact, and thematic evolution of scientific production on ehrlichiosis in veterinary medicine
Authors: Espinoza-Carhuancho Fran , Medina Julia , Mauricio-Vilchez Cesar , Galarza-Valencia Diego , Mendoza Roman , Pacheco-Mendoza Josmel , Mayta-Tovalino Frank
Published: September 2024

Background and Aim: This study focuses on the scientific output of ehrlichiosis, a tick-borne disease that affects a variety of animal species, including dogs, cats, and livestock. Therefore, this study aimed to perform a scientometric mapping of the trends, impact, and thematic evolution of scientific production on ehrlichiosis in veterinary medicine.

Materials and Methods: The study design was descriptive and observational, with a quantitative scientometric approach. This study was based on Scopus data collection and analysis from 2018 to 2023. A literature search was conducted on February 12, 2024, and a total of 200 documents were found, of which 177 were articles, 15 book chapters, and eight reviews. A specific search formula was used to obtain documents. The documents were analyzed using SciVal and Bibliometrix in R Studio, focusing on four key metrics: Scholarly Output, View Count, Field-Weighted Citation Impact, and Citation Count.

Results: This bibliometric study covered the period from 2018 to 2023 and analyzed 200 papers from 84 different sources. The average number of citations was 3595 and the mean age was 3.17 years. A total of 1874 keywords and 1085 authors were identified, with an average of 6.25 co-authors per paper. International co-authorship was present in 23% of the papers. The papers were distributed as articles (177), book chapters (15), and reviews (8).

Conclusion: The combination of these metrics enabled a more complete and accurate assessment of research performance. A total of 1874 keywords and 1085 authors were identified. The thematic evolution from “canine ehrlichiosis” and “Ehrlichia canis” to “dog” and “canine” was observed. Bradford’s and Lotka’s laws were confirmed, with some sources and authors generating most publications.

Keywords: bibliometrix, ehrlichiosis, scientometric.
Genetic characterization of low-pathogenic avian influenza subtypes H10N6 and H10N7 from free-grazing ducks in Thailand
Authors: Boonyapisitsopa Supanat , Chaiyawong Supassama , Charoenkul Kamonpan , Udom Kitikhun , Chamsai Ekkapat , Jairak Waleemas , Tunterak Wikanda , Bunpapong Napawan , Amonsin Alongkorn
Published: September 2024

Background and Aim: Free-grazing duck (FGD) raising is a unique domestic duck production system that is widely practiced in several Asian countries, including Thailand. FGD is a significant reservoir for influenza A viruses (IAVs). In this study, we genetically characterized IAV-H10N6 and IAV-H10N7 isolated from avian influenza surveillance in FGDs in Thailand.

Materials and Methods: We collected 640 swab samples from 29 FGD flocks located in 6 provinces of Thailand. IAVs were isolated from swab samples using egg inoculation. Hemagglutination test-positive samples were then subjected to IAV detection. Viral RNA was subjected to IAV detection using real-time reverse-transcription polymerase chain reaction (rRT-PCR) specific to matrix (M) gene. IAV subtypes were identified using the RT-PCR assay specific to all hemagglutinin and neuraminidase subtypes. Whole-genome sequencing of IAVs was performed to genetically characterize IAV-H10N6 and IAV-H10N7.

Results: Our results showed that 41 (6.41%) samples tested positive for IAV using rRT-PCR specific to the M gene. Among these, only two IAVs were subtypes as IAV-H10N6 and IAV-H10N7 and were subjected to whole-genome sequencing. IAV-H10N6 and IAV-H10N7 belonged to the Eurasian lineage and did not show any evidence of reassortment from the North American lineage. The viruses exhibited low-pathogenic characteristics and preferred binding to avian-type receptors. Genetic analysis revealed no mutations in PB2 and M genes, unlike human IAV-H10N3 and IAV-H10N8, which exhibited increased virulence in mammals.

Conclusion: IAV-H10N6 and IAV-H10N7 viruses have less potential as zoonotic viruses. However, IAV in FGDs should be monitored for novel reassortant or zoonotic viruses. This study provides information on the genetic characteristics and diversity of IAV-H10N6 and IAV-H10N7 that are circulated in FGDs in Thailand.

Keywords: free-grazing ducks, genetic characterization, H10N6, H10N7, influenza A virus.