bluuebunny/crossref_metadata_2025 huggingface dataset:
PENGARUH PEMBERIAN TOPIKAL EKSTRAK KOLAGEN KULIT IKAN LELE SANGKURIANG (CLARIAS GARIEPINUS VAR) TERHADAP TNF-Α DAN JUMLAH FIBROBLAST PADA LUKA BAKAR DERAJAT DUA TIKUS WISTAR
Authors: . Aisyah , Mufarikoh Zainatul , Andini Ary
Published: November 2018

ABSTRACTBackground: Collagen has vital role on healing process of burn injuries, mainly in connective tissue.Collagen triggers fibroblast proliferation, support to form new granulation tissue and epithelium aroundwound. Wound treatment through collagen extract of Sangkuriang catfish skin can increase healing process.It stimulates humidity on level II burn injuries and encourage re-epithelization, proliferation and cellmigration also increases growth. Methods: This is an experimental studies using 4 groups of RattusNorvegicus (Wistar strain). All of the group get a burn injuries in their back skin. Control group 1 (K1) wastreated by lidocaine for three days and control group 2 (K2) for ten days. Whereas treatment group 1 (P1) getlidocaine and collagen extract from Sangkuriang cat fish for 3 days and treatment group 2 (P2) for 10 days.Result: Number of fibroblast/field of view on treatment group showed significantly increased comparedcontrol groups on the 3rd days (P=0,046) and the 10th (P=0,004). Percentage of TNF-α on level II-burninjuries in wistar rats showed significant difference. Percentage of TNF-α lower than treatment group andshowed significant lowering level compared control groups on the10th (P=0,022). Conclusion: Increasing offiroblast number and lowering level of TNF-α significantly showed collagen extract of Sangkuriang cat fishskin accelerate wound healing process.
PENGARUH PEMBERIAN VITAMIN C, VITAMIN E, DAN KROMIUM (CR3+) TERHADAP KADAR INSULIN TIKUS WISTAR YANG DIINDUKSI ALOKSAN
Authors: Mutiarani Anugrah Linda
Published: November 2018

Objective: To analyze the effect of vitamin C, vitamin E, and chromium (Cr3+) on insulin levels Wistar ratswere induced alloxan.Materials and Methods: This study is an experimental laboratory. Using rats typeWistar strain Rattus novergicus for 6 weeks with a number of 20 head. The independent variables consist of 5treatment groups namely normal diet, normal diet + 1 g/hr chromium, normal diet + 2 mg/day of vitamin C,normal diet + 0.5 mg/day of vitamin E, normal diet + 1 g/hr chromium + 2 mg/day of vitamin C + 0.5mg/day of vitamin E. The dependent variable is the level of insulin. To know the differences of eachtreatment used statistical tests One Way ANOVA, followed by Tukey HSD Post Hoc test withp<0.05.Results: There were significant differences in insulin levels (p<0.05) in the control group, 1, 2, and 4.But in the control group and the group 3 there are no significant differences in insulin levels (p=0.145).Conclusion: Delivery of chromium (treatment 1), vitamin C (treatment 2), and a mixture of chromium,vitamin C, vitamin E (treatment 4) effect on insulin levels, while administration of vitamin E (treatment 3)alone had no effect on insulin levels
HUBUNGAN ANTARA KADAR TROPONIN DENGAN KEJADIAN MAJOR ADVERSE CARDIOVASCULAR EVENTS PADA PASIEN SINDROM KORONER AKUT DI RSI JEMURSARI SURABAYA
Authors: Kusumawati Elsa , Firdaus Abraham Ahmad Ali , Putra Reza Hery Mahendra
Published: November 2018

Abstrak: Sindroma Koroner Akut (SKA) memiliki variabilitas yang cukup besar dalam risiko outcome dan mortalitas. Major Adverse Cardiovascular Events (MACE) adalah hasil akhir SKA yangdidefinisikan sebagai aritmia, syok kardiogenik, gagal jantung, dan kematian. Troponin adalah protein spesifik yang berasal dari otot jantung, di mana fungsinya adalah regulasi kontraksi otot jantung.Kejadian MACE sering ditemukan pada pasien SKA meskipun pasien telah menjalani perawatanintensif. Dengan demikian, dibutuhkan prediksi awal yang besar untuk mengetahui risiko MACEpada penderita SKA, dalam hal ini berupa troponin. Penelitian ini bertujuan untuk mengetahuikadar troponin yang meningkat, sehingga dapat lebih berhati-hati mencegah kejadian MACE padapasien SKA. Cross-sectional pada pasien SKA yang dirawat di RSI Jemursari Surabaya pada bulanJanuari 2014–Desember 2016. Pengambilan sampel dengan teknik consecutive sampling, sebanyak68 orang. Data dianalisis dengan uji chi-square. Penderita laki-laki lebih banyak dibandingkan denganpenderita perempuan. Kelompok usia terbanyak yang menderita SKA adalah 56-65 tahun, denganrentang usia 35-85 dan rerata usia 59, 45±11,447 tahun. Hasil penelitian ini menunjukkan bahwaterdapat korelasi antara peningkatan troponin dengan kejadian Major Adverse Cardiovascular Events(MACE) pada pasien sindrom koroner akut dan nilai signifikansi p<0,002. Hasil Odss Ratio (OR)pada pasien SKA dengan peningkatan troponin sebesar 6,5 (IK 95% 2,112-20,282) p<0,002. Adakorelasi antara peningkatan kadar troponin dengan kejadian Major Adverse Cardiovascular Events(MACE) pada pasien dengan sindrom koroner akut.
EPILEPSI POST TRAUMA DENGAN GEJALA PSIKOTIK
Authors: Irfana Lailiy
Published: November 2018

Abstrak: Data WHO menunjukkan epilepsi menyerang 1% penduduk dunia. Angka kejadian epilepsimasih tinggi terutama di negara berkembang yaitu mencapai 114 per 100.000 penduduk per tahun.2 Padakelompok dewasa muda, epilepsi dapat terjadi salah satunya disebabkan oleh trauma kepala.3 Kasus inimelaporkan penderita laki-laki usia 24 tahun dengan keluhan kejang yang disertai dengan gejala psikotik.Didapatkan riwayat pasien kejang pertama kali dua bulan setelah mengalami trauma kepala yaitu padatahun 2003. Saat itu pasien mengalami cedera otak berat dan dari CT scan kepala didapatkan perdarahandi otak. Dua bulan setelah trauma kepala itu pasien mengalami kejang berulang disertai keluhan yangdominan adalah marah-marah hingga pernah sampai mau membunuh orang. Dari analisis EEGmenunjukkan hasil epilepsi lobus frontotemporal. Setelah pasien mendapatkan pengobatan phenytoindan risperidone, kejang mulai terkontrol. Namun bila tidak minum obat pasien kejang lagi. Hal inidialami oleh pasien hingga saat kasus ini dilaporkan, yaitu sepuluh tahun post trauma.
Pengaruh Kebutuhan Gizi Terhadap Perubahan Berat Badan Ibu Hamil di Desa Petis RT 02 RW 02 Kecamatan Duduk Sampeyan Kabupaten Gresik
Authors: Setiyowati Eppy , Emilyati Desi
Published: November 2018

Pregnancy caused by changes in body weight of pregnant women, which is not significantly impact on the growth of the fetus in the womb, experiencing anemia and low birth weight. The purpose of this study analyzed the nutritional needs of pregnant mothers to changes in maternal and fetal body weight in the Village District of RW 02 Petis Duduk Sampeyan Gresik. Analytical study design with cross sectional study design. The population is all pregnant women in the village of RT 02 RW 02 Petis Sitting Sampeyan District of Gresik by 33 people. Sampling sampling techniques with simple random sampling. The instrument uses observation. This variable is the nutritional needs of pregnant women and changes in maternal and fetal body weight. Data were analyzed with the Mann-Whitney test with α = 0.05. The result showed the majority (66.7%) of respondents need good nutrition. As well as the vast majority (66.7%) of respondents normal weight. It can be concluded that there is influence the nutritional needs of pregnant mothers to changes in maternal and fetal body weight in the Village District of RW 02 Petis Sitting Sampeyan Gresik. More nurses can improve the promotion program to improve maternal and fetal body weight through promotion and education in local communities about the importance of maternal and fetal weight
HUBUNGAN TINGKAT PENGETAHUAN DENGAN KEPATUHAN PENGGUNAAN ALAT PELINDUNG DIRI (APD) PADA PEKERJA MEKANIK DI AREA WORKSHOP PT. XYZ KOTA SURABAYA
Authors: Ayu Friska , R Muslikha Nourma , Sunaryo Merry
Published: November 2018

Along with the rapid development of industry encourages the increasing use of machinery, work equipment in the process of produsi with accompanied the application of techniques and technology from various levels in all sector. This means that there maybe a high risk of accidents due to work and also an increase in the amount of intensity of hazard sources in the workplace. Using of Personal Protective Equipment (PPE) is the final stage of hazard control, although the use of PPE will be maximized if other controls such as elimination, substitution, enginee was already applied. This research was conducted at PT.XYZ which is one of the companies engaged in the delivery of goods through sea lanes located in Tanjung Perak, Surabaya by using analytical observational method with a cross sectional study design with a total sample of 38 people. The characteristics of the respondents and the level of compliance with the use of PPE were obtained from interviews with mechanical workers in the workshop area. From the results of interviews conducted, as many as 24 mechanical workers obedient in using PPE and 14 others are not obedient in using PPE. The result of statistical test using chi square test shows that there is correlation between knowledge level (p = 0,002) with level of compliance of PPE usage on mechanical worker in workshop area. Advisable for workers to further improve compliance and self-awareness in using personal protective equipment (APD) while working or while in the work environment because its relates to the personal health and safety of workers. For the company should be more firm in supervising the worker in this case about the habit of using personal protective equipment in accordance with the policy set.
GAMBARAN POLA MAKAN TERHADAP STATUS GIZI SISWA DI SD PUTRA INDONESIA SURABAYA
Authors: Sunaryo Merry
Published: November 2018

Nutrition problems faced by the Indonesian nation has become more complete with many nutritional problems in children. Basic Health Research Data (RISKESDAS) in 2010 shows that Indonesia nutritional status of children aged 6-18 years as much as 35.4% is very short, as many as 66.6% are classified as short, as many as 4.6% are very thin as 9.1%, As much as 22.1% and as much as 13.1% belong to the fat. This research is an observational research and descriptive research with cross sectional design and by using quantitative approach. The sample in this research is the students of grade 4, 5, and 6 SD Putra Indonesia. The number of samples is 93 students which the total sampling method, the use of this method because the population number is not more than 100 people. The results obtained most of the diet respondents in general that most do not do breakfast, do not bring food supplies to school and like snack at school. Based on the results of assessment of nutritional status obtained information that the nutritional status of respondents based on BMI assessment If the calculated number of students with abnormal weight that is equal to 58.1%. Participants who had BMI assessment with normal weight category were 39 people (41.9%). Therefore, it is known that most students have an abnormal BMI. Generally, it takes considerable extra attention for parents and teachers to be able to monitor children in the intake of nutrition and healthy eating patterns. In order to improve the nutritional status of children who are now in its infancy.
EFEKTIFITAS PENAMBAHAN SERBUK KUNYIT TERHADAP BILANGAN PEROKSIDA DAN BILANGAN ASAM MINYAK GORENG BEKAS PAKAI
Authors: Mardiyah Siti
Published: November 2018

Used cooking oil is leftover cooking oil from food frying processes that have been used repeatedly. This resulted in increased high free radical and fatty acid content which can be harmful to health. One attempt to reduce oil damage is with the addition of antioxidants. Curcumin is an antioxidant contained in turmeric. Curcumin is an antioxidant phenol which have many double bonds that can capture free radicals, which can slow down the increase in the peroxide and acid number of used cooking oil. The purpose of this study was to determine the effect of turmeric powder on levels of acid number. This type of research is experimental by the number of samples in each treatment and as many as 16 samples. Formulation of the problem of this study is whether there is the effect of turmeric powder on levels of acid value on used cooking oil. The examination results on the levels of acid number of used cooking oil shows the average levels of the acid number of used cooking oil which without the provision of turmeric powder is as high as 0,641, while the one with the provision of turmeric powder is as high as 0,349. Statistical analysis by t test showed the effect of turmeric powder on levels of acid value on used cooking oil with value of p (sig) = 0.000 which is less than 0.05. Therefore, the turmeric powder can inhibit the decrease of acid number on used cooking oil so that the oil quality is maintained.
ANALISIS STATUS GIZI TERHADAP TINGKAT KELELAHAN KERJA PADA PEKERJA DIVISI KAPAL PERANG PT.PAL INDONESIA (PERSERO)
Authors: Adriansyah Agus Aan , Imanniyah Tri Asih , Handayani Handayani
Published: November 2018

Tenaga kerja yang bekerja di area lingkungan kerja yang panas dengan jangka waktu lama dapatmempengaruhi kesehatan dan kelelahan kerja serta penurunan daya otot. Kelelahan kerja dapatdisebabkan salah satunya adalah status gizi pekerja. Jika tenaga memiliki status gizi kurus danmendapatkan beban kerja berat serta melakukan banyak aktivitas fisik yang menimbulkan keringat,maka seseorang tersebut mudah mengalami kelelahan kerja. Meningkatnya kelelahan kerjamemberikan peluang terjadinya kecelakaan kerja dalam industri. Penelitian ini bertujuanmenganalisis status gizi terhadap tingkat kelelahan kerja. Penelitian ini menggunakan desainobservasional analitik dengan pendekatan studi cross sectional. Populasi pada penelitian inimerupakan pekerja Divisi kapal perang PT. PAL Indonesia (Persero) sebanyak 80 pekerja. Sampelyang digunakan sebesar 67 pekerja dengan teknik pengambilan sampel menggunakan simple randomsampling. Pengumpulan data dilakukan dengan menggunakan kuesioner dan pengukuran IndeksMasa Tubuh (IMT). Analisis data menggunakan uji regresi logistik binery. Hasil penelitian

menunjukkan sebagian besar pekerja memiliki status gizi kurus (53,7%) dan mengalami tingkatkelelahan kerja kategori sedang (52,2%). Nilai signifikansi dari status gizi terhadap tingkat kelelahankerja sebesar 0,011 (p.value <0,05). Hal ini menunjukkan terdapat pengaruh yang signifikan antarastatus gizi terhadap tingkat kelelahan kerja pada pekerja Divisi Kapal Perang PT.PAL Indonesia(Persro). Kesimpulan dari penelitian ini adalah pekerja yang memiliki status gizi kurus cenderungmengalami tingkat kelelahan kerja tinggi. Perusahaan maupun pekerja diharapkan dapatmemperhatikan makanan yang dikonsumsi sesuai dengan kebutuhan kalori tubuh, agar selamabekerja tidak mengalami kelelahan kerja.
Teacher’s Opinion Regarding Potential use and Misuse of Teachers’ Evaluation in Undergraduate Dental Education
Authors: Amin Md Shoheilul , Khan Ismail , Talukder Md Humayun Kabir , Ansary Jamil Ahsan
Published: November 2018

Teachers' evaluation in our country is yet to be started. But in many countries of the world it has been adopted a long time ago. It not only affects the teaching process but also motivate teachers for self-development. It is a series of activities and actions that are interconnected and relate to a specific purpose. In the last two decades, the importance of teaching evaluation has been emphasized in higher education. Many medical and dental schools have searched for ways to effectively and constructively evaluate performances of their faculty members. This cross-sectional descriptive study conducted among the teachers of public & private dental colleges adopting convenience sampling. Study revealed that teacher evaluation can improve teacher's teaching ability (94.1%), it can be used to assessing training need of the teacher (94.1%), it can protect students from incompetent teachers (91.2%), it can be used for promoting teachers (91.2%), it can also help to monitor the performances of teacher by administrators (88.2%), The most common sources of evaluation data have been students, peers, and teachers themselves. Teacher evaluation is often designed to serve two purposes- to measure teacher competence and to foster professional development and growth. A teacher evaluation system give teachers useful feedback on classroom needs, the opportunity to learn new teaching techniques, and counsel from principals and other teachers on how to make changes in their classrooms. The goal of any effective evaluation process must be growth of good teacher.Bangladesh Journal of Medical Education Vol.9(2) 2018: 24-26
Evaluation of antimicrobial resistance pattern of uropathogens in a tertiary care hospital in Dhaka city, Bangladesh
Authors: Nahar Azizun , Hasnat Shahed , Akhter Hasina , Begum Nilufar
Published: November 2018

Urinary tract infection (UTI) is one of the most common bacterial infections seen in developing countries like Bangladesh. This study is, therefore, designed to determine the bacterial uropathogens and their antibiotic resistance pattern among patients with complaints of UTIs in Dhaka city. This study was carried out in the laboratory of the Department of Microbiology, Bangladesh Medical College, Dhaka, Bangladesh from January to June 2015. A total of 2541 urine samples were collected in sterile containers from suspected urinary tract infected cases. A specimen was considered positive for UTI if an organism was cultured at a concentration of ≥105CFU/ml or when an organism was cultured at a concentration of 104CFU/ml and >5 pus cells per high power field. Antimicrobial susceptibility testing of the isolated bacterial species was performed by disc diffusion method following the National Committee for Clinical laboratory Standards (NCCLS) guidelines. A total of 303 (11.92%) bacterial uropathogens were isolated from 2541 urine samples. Among the 303 isolates, majority of the isolates 197 (65.02%) were from females. Both the age groups up to 18 years and above 18 years the highest prevalence was found in females 34(11.22%) and 163 (53.79%) respectively. Most predominant organism was Escherichia coli 262(86.46%)followed by Pseudomonas 12(3.96%), Enterococci 12(3.96%), Klebsiella11(3.63%). Escherichiacoli showed very high resistance to amoxycillin 95.41%, cefradin 90.45%, nalidixic acid and Klebsiella to amoxycillin 90.90%, nitrofurantoin 90.90%. Again Pseudomonas was highly resistant to cefuroxime 100%, cefexime 100%and ceftriaxone 83.33%. Enterococci were found highly resistance to cefexime 91.66%, cloxacillin 83.33%, and erythromycin 83.33%.Due to wide scale resistance of the drugs used to treat UTI, choice of drugs in the treatment of UTI is quite narrow. In country like ours awareness for prevention of UTI should be encouraged among the community level as it affects all age groups.South East Asia Journal of Public Health Vol.7(2) 2017: 12-18
Expectations of adolescents to receive reproductive health information and services from health service system: A qualitative study in Bangladesh
Authors: Yunus Samiha , Sharmin Sabrina , Huq Nafisa Lira , Haseen Fariha , Imam Md Ali , Nahar Quamrun
Published: November 2018

Adolescents, aged 10-19 years, constitute one fifth of Bangladesh's total population of 158 million. Similar to adolescents elsewhere, Bangladeshi adolescents also have special sexual and reproductive health (SRH) information and service needs; however, these needs are not adequately addressed by the existing health service system. The present study was conducted to identify adolescents’ expectations of and preferences for receiving SRH information and services. This qualitative study was conducted in six purposively selected areas of Bangladesh using 20 Key Informant Interviews (KII) during September-November 2012. Key informants aged between 15 to 19 years were leaders of youth organizations or class monitors in school. Informants were unmarried and married, males and females, and from rural and urban areas. This study identified that there is a strong need for SRH services for adolescents. Irrespective of their residence and gender, adolescents preferred health service providers to be qualified medical doctors, who are experienced, well-trained and polite. Availability of doctors, maintaining privacy and treatment through counseling were mentioned as their priorities. Both urban and rural adolescents recommended establishing adolescent friendly environment in every government and NGO health service facility. They also asked for gender specific service provider for female and male adolescents. Urban adolescents expressed the need for school health program with provision of school health clinics. On the other hand, rural adolescents recommended for community health workers to raise awareness on adolescent sexual and reproductive health (ASRH) issues with parents and families. The adolescents also expected to receive SRH information through mass media, school curriculum, and booklets on adolescent SRH, and peer educator. Addressing the expectations of adolescents will open a new skylight to policy makers to design highly accessible health services for adolescents in BangladeshSouth East Asia Journal of Public Health Vol.7(2) 2017: 19-26
Aripiprazole is effective in hyperprolactinemia secondary to use of Fluphenazine
Authors: Shah Smit , Shah Pooja , Salaria Salman , Salaria Osman
Published: November 2018

Aripiprazole is drug that acts as a partial agonist at D2 and 5-HT1A receptors and antagonist at 5-HT2A receptor. It modulates the neurotransmission over activity on the dopaminergic mesolimbic pathway which is responsible for positive symptoms of Schizophrenia. Dopamine antagonism is the mechanism of action of first generation antipsychotics. In this paper we discuss an interesting case in which Aripiprazole was effective in decreasing Prolactin levels which was elevated secondary to previous Fluphenazine use.South East Asia Journal of Public Health Vol.7(2) 2017: 40-42
Public Health: Emerging and Re-emerging Issues
Authors: Majumder Md Anwarul Azim , Kabir Russell , Rahman Sayeeda
Published: November 2018

Abstract not availableSouth East Asia Journal of Public Health Vol.7(2) 2017: 43
Conference proceedings Section-3: 5th Public Health Foundation day & International Conference with Health Fair 2017
Authors: Majumder Md Anwarul Azim
Published: November 2018

Abstract not availableSouth East Asia Journal of Public Health Vol.7(2) 2017: 69-116
Isolation and Characterization of Hypolipidemic Compound from Cajanus cajan
Authors: Habib M Anwar , Anisuzzaman ASM , Barman RK , Gafur M Abdul , Haque M Tofazzal
Published: November 2018

The study was carried out to identify the compound responsible for hypolipidemic and hypoglycemic effects of Cajanus cajan (redgram). The methanol extract of redgram seeds was found to decrease fasting blood glucose and lipid profile (p<0.001) on streptozotocin-induced mice compared to control. This activity- guided fraction led to the isolation of a compound, substituted benzene containing polyhydroxy functions fused with lactone (CCA3) by analysis of 1H and 13C-NMR data. Biological studies of the isolated compound possessed prominent hypolipidemic activity. Although a number of hypoglycemic compounds are reported, yet not any hypolipidemic compound from redgram. The compound CCA3 seems to be the first report on hypolipidemic activity from methanol extract of redgram.

TAJ 2011; 24(1): 6-10
Intussusception Secondary to Isolated Heterotopic Pancreas of Meckel’s Diverticulum
Authors: Nowshad A , Shahid SMA , Islam SS , Mostaque A
Published: November 2018

Intussusception in the pediatric age group is usually idiopathic in origin, and in a small number of patients ranging from 2% to 12%, a pathological lesion as a leading point is identifiable. Of the variety of pathologcial lesions identified as leading points for intussusception, Meckel’s diverticulum is the most common but very rarely, isolated heterotopic pancreas is found within it.This is a case report of intussusception in an infant caused by an isolated heterotopic pancreas of the Meckel’s diverticulum. The literature on the subject is also reviewed.

TAJ 2011; 24(1): 16-20
Role of Lumbar Puncture for First Simple Febrile Seizure Among Children 6 to 18 Months of Age
Authors: Haque M Sanaul , Yeasmin Shahida , Dutta Poly , Kumar PK Chandan , Kundu Pijush Kumar
Published: November 2018

Introduction: Fever with seizure is a common childhood emergency. This may be due to febrile seizure or CNS infection like meningitis. Febrile seizure makes up the most common convulsive event in children 6 months to 5 years of age. Despite the commonness of this clinical problem, the need for routine lumbar puncture following a first simple febrile seizure below 18 months of age to exclude meningitis continues to be debated.Objectives: To evaluate the role of lumbar puncture for first simple febrile seizure among children 6 to 18 months of age and to determine the causes of fever of the patient presented with fever with simple seizure in this age group.Methodology: This cross-sectional type of descriptive study was conducted at Paediatric department of Rajshahi Medical College from January 2013 to December 2014.A total of 73 children ages 6 months to 18 months with first simple febrile seizure were enrolled by purposive sampling technique. Lumbar puncture was performed in all patients to evaluate occult meningitis.Results: A total of 73 children ages 6 months to 18 months with first simple febrile seizure were included in the study. 37% (n = 27) were < 12 months of age and 63% (n = 46) were ≥12 months of age with a mean age 13±3.575 months. 43.8% of our study population had family history of febrile seizure. CSF findings of all children > 12 months of age group 63% (n = 46) were normal but in case of age group <12 months, out of 37% (n = 27) cases, only one case showed abnormal CSF finding.Conclusion: It is concluded that lumbar puncture following first simple febrile seizure without any other features of meningitis may be done in children < 12 months of age.TAJ 2011; 24(2): 65-69
Laparoscopic Orchiopexy for the Nonpalpable Testis : 3 Years Experience
Authors: Ali M Nowshad , Khatun M Rokeya , Shahid SMA , Ahmed M , Das Chinmoy Kanti
Published: November 2018

We evaluated the safety and efficacy of laparoscopic orchiopexy to manage a nonpalpable intra-abdominal testis and studied the outcomes. We report our 3 years experience.Patients and methods Laparoscopic Orchiopexy was performed on 28 children (32 testicular units) for non-palpable intra-abdominal testis between 2010 and 2012. We retrospectively reviewed the medical records. The mean age was 3.4 years (range, 2.5 -11 years). Of the 28 patients, 18 (64.28 %) were on the right, 6 (21.44%) were on the left and 4 (14.28%) of bilateral. The mean follow-up period was 14.8 months (range, 3-36 months). Testicular viability and orchiopexed positioning were evaluated within 1 month and beyond 3 months.Results  Thirty one testes were descended successfully by laparoscopy. The average operative time was 41.5 ± 3.8 min. Primary laparoscopic orchiopexy done in 26 testes.Three of unilateral and 2 of bilateral testicular units underwent one -stage Fowler-Stephens Orchiopexy. One patient needs laparoscopic orchiectomy. At follow-up (mean 14.8 months), one testis atrophied and need orchiectomy. Testicular survival rate was 96.77% (30/31) and all of the testes maintained an adequate size. Twenty six (86.66%) are in an acceptable scrotal position and 4 testes (13.33%) are mid to high in the scrotum without atrophy. There was no recurrent inguinal hernia.Conclusions  Laparoscopic orchiopexy is successful for a nonpalpable intra-abdominal testis with a high testicular survival rate. The low incidence of complications and high success rate underscore the feasibility of this procedure. It is our procedure of choice for the treatment of nonpalpable testis.TAJ 2011; 24(2): 70-75
Bevacizumab in Neoadjuvant Treatment of Patients with Liver Metastases from Colorectal Carcinoma
Authors: Uddin Dayem , Khan MMR , Rahman ASMM , Habib Shafayat , Sultana Shakera
Published: November 2018

Liver metastases are the leading cause of death in patients with colorectal cancer Despite advances in chemotherapy, surgical resection of hepatic metastases is still considered the only curative treatment the majority of patients have inoperable disease at presentation. Perioperative chemotherapy is the most successful way for improved selection of patients for resection. The aim of the study was to demonstrate if and to what extent does bevacizumab, introduced in chemotherapy, increase response rates, and development of liver metastases. Our study included 25 patients who were divided in two groups. The experimental group included patients who were treated with bevacizumab plus chemotherapy and the control group included patients who were treated with chemotherapy only. The comparison showed that the patients who were treated with bevacizumab became candidates for resection of liver metastases in higher percentage (85%:52%). On the otherhand distribution of patients regarding the development of metastases resulted in statistically significant difference. Ratio between the patients with good response from the experimental and the control group was 67%:39%. Ratio of patients with stable disease was 26%:48%, and of patients with progressive disease, it was 7%:3%. The estimate of margin after resection was statistically insignificant.TAJ 2011; 24(2): 101-105
Role of Bolus Dose of Fentanyl (4μgm/kg) in Attenuating Presser Response of Laryngoscope and Tracheal Intubation
Authors: Azad AK , Taher SMA , Raihan Jamil , Zahid M Abu , Alam M Intekhab
Published: November 2018

Fentanyl is an opoid drug. It is effective in controlling pain during intra operative period. It was also observed thermodynamically state intra operatively. Hence it was planned to attenuating the hypertensive and tachycardiac response to laryngoscopey and trachel intubation by using bolus dose of Fentanyl (4μgm /kg).TAJ 2011; 24(2): 124-127
Comparative Study of Hicrome Agar Medium with Conventional Culture System for the Isolation of Uropathogens
Authors: Nahar S Gul , Hasan M Bulbul , Khatun Mst Rokeya , Ali M Nawshad
Published: November 2018

Objective: The present study was done to compare the performance of chromogenic agar medium and conventional culture media for the isolation and presumptive identification of uropathogen.Methodology: A total 300 sample were collected from Rajshahi Medical College Hospital, Bangladesh during January to June, 2008. Urine samples of the suspected UTI cases, showing pus cells >5/HPF on microscopic examination were included for urine culture simultaneously onto 2 conventional media (Blood agar and MacConkey agar) and chromogenic agar medium (HiCrome UTI agar medium). Results: Culture yielded 139 (46.33%) bacterial growth among them, 133 (44.33%) showed single organism and remaining 06 (2.00%) showed mixed growth of two organisms in different combinations. It is evident from the present study that both HiCrome UTI agar and Blood agar (BA) media supported growth of all 145 bacteria, while MacConkey (MAC) agar yielded 133(91.72%) bacterial growths. The rate of presumptive identification of the isolates was found significantly higher (97.24%) on HiCrome UTI agar when compared with the MacConkey agar (80.68%) and Blood agar (27.58%) media. Out of 91 E. coli isolated, 88(96.70%) could be identified differentially on HiCrome UTI agar medium in contrast to 85(93.40%) on MacConkey agar and only 06(06.59%) on Blood agar. Again, all 06 (100%) of the isolate-pairs of mixed growth were identified distinctly on HiCrome UTI agar, whereas both Blood agar and MacConkey agar media could revealed only 01(16.66%) of the polymicrobial growth.Conclusion: HiCrome UTI agar medium has been documented for its very high yielding rate, rapid presumptive identification of both single and polymicrobial growths with greater precision and avoidance of biochemical tests for further identification of uropathogens. Thus it can be recommended as primary urine culture medium to be used by the clinical microbiology laboratories.TAJ 2011; 24(2): 128-135
Quality Assurance in Medical Education
Authors: Haque M Zahirul
Published: November 2018

Abstract not availableTAJ 2012; 25: i
Association Between Diabetes Mellitus and Secretor (ABH) Status
Authors: Alam MM Ul , Islam Monwarul , Khan MMR , Rahman MK
Published: November 2018

Five hundred and seventy seven patients with diabetes mellitus showed ABO blood group frequencies closely similar those expected from the controls. Four hundred and eleven patients with diabetes mellitus showed frequencies of secretion and non-secretion of the ABH (O) substances in the saliva closely similar to those expected from the controls. three hundred and two patients with diabetes mellitus gave MN blood groups frequencies very similar to those expected from the controls.TAJ 2012; 25: 38-41
Balanced Anesthesia VS General Anesthesia for Upper Abdominal Surgery-A Comparative Study of Outcome
Authors: Zahid M Abu , Alam Intekhab , Haque AKM Tanvirul , Sultana Sharmin , Taher SMA , Azad AK , Raihan Jamil
Published: November 2018

This is a prospective randomized clinical study was done in the dept. of Rajshahi Medical College Hospital & in different Clinics in Rajshahi city from August 2013 to December 2014 to evaluate the outcome of patient undergoing upper abdominal surgery such as cholecystectomy, cholidocholithotomy, Nephrolithotomy, Gastrojejunestomy, Splenectomy, Hysterectomy, LUCS, Appendisectomy etc. by balanced anesthesia. This is also a comparative study of patient undergoing upper abdominal surgery either by balanced anesthesia or by general anesthesia. For this study 80 patients of upper abdominal surgery were randomly selected in two groups (Each group contain 40 patients) Group 'A' Patient received balanced anesthesia & group 'B' Patient received general anesthesia. Then these patient were monitored during per-operative & post operative period to evaluate its outcome. After completion of operation we have seen that those patent received balanced anesthesia had better outcome than general anesthesia undergoing upper abdominal surgery.TAJ 2012; 25: 47-54
Chromogenic Agar Medium : A Versatile Tool for the Diagnosis of UTI
Authors: Nahar S Gul , Hasan M Bulbul , Khatun Mst Rokeya , Ali M Nawshad , Mohanta DK
Published: November 2018

Objective: The present study was done on Chromogenic agar media to identify uropathogens more efficiently by its characteristic colony colour for each of the organism.Methodology: A total 300 sample were collected from Rajshahi Medical College Hospital, Bangladesh. Urine samples of the suspected UTI cases, showing pus cells >5/HPF on microscopic examination were included for urine culture simultaneously onto Chromogenic agar media, Blood agar and MacConkey agar media.Results: Culture yielded 139 (46.33%) bacterial growth among them, 133 (44.33%) showed single organism and remaining 06 (2.00%) showed mixed growth of two organisms in different combinations. It is evident from the present study that both Chromogenic agar media and Blood agar (BA) media supported growth of all 145 bacteria, while MacConkey (MAC) agar yielded 133(91.72%) bacterial growths. The rate of presumptive identification of the isolates was found significantly higher (97.24%) on Chromogenic agar media when compared with the MacConkey agar (80.68%) and Blood agar (27.58%) media. Out of 91 E. coli isolated, 88(96.70%) could be identified differentially on Chromogenic agar media in contrast to 85(93.40%) on MacConkey agar and only 06(06.59%) on Blood agar. Again, all 06 (100%) of the isolate-pairs of mixed growth were identified distinctly on Chromogenic agar media, whereas both Blood agar and MacConkey agar media could revealed only 01(16.66%) of the polymicrobial growth.Conclusion: Chromogenic agar media has been documented for its very high yielding rate, rapid presumptive identification of both single and polymicrobial growths with greater precision and avoidance of biochemical tests for further identification of uropathogens. Thus it can be recommended as primary urine culture medium to be used by the clinical microbiology laboratories.TAJ 2012; 25: 64-71
A Case of Kikuchi’s Disease Presenting with Fever and Lymphadenopathy
Authors: Khan MMR , Rahman MK , Basak PM , Khanam K , Pal BK , Islam MJ , Khan FA , Newaz MM , Das HS
Published: November 2018

Kikuchi’s disease is a rare, benign, self-limiting disorder, characterized clinically by fever and regional lymphadenopathy. Histopathologic features of lymph nodes in Kikuchi’s disease are characteristic and permit differentiation of this benign condition from lymphomas, systemic lupus erythematosus and infectious lymphadenopathies. We report a female patient presenting with fever and tender cervical lymphadenopathy. An excisional biopsy of the lymph node reveale lymphadenitis, consistent with Kikuchi’s disease.TAJ 2012; 25: 81-83
Right Ventricular Myocardial Infarction as an Independent Predictor of Prognosis in Acute Inferior Myocardial Infarction
Authors: Huda Nazmul , Sayeed Zahidus , Ekram ARMS , Khan MMR , Rahman MK
Published: November 2018

Background: Acute inferior myocardial Infarction frequently involves the right ventricle and associated with significant morbidity and mortality. We hypothesized that right ventricular involvement may affect the prognosis of patients with inferior myocardial infarctions.Methodology: In 100 consecutive patients admitted to the hospital with acute inferior myocardial infarction, we assessed the incidence and prognostic factors for in-hospital outcome. RVMI (Right ventricular myocardial infarction) was diagnosed by ≥1mm ST elevation in lead V4R in right sided electrocardiogram.Result: RVMI was found in 31(31%) of patients of acute inferior myocardial infarctions. Major complications as hypotension and cardiogenic shock occurred in 96.7% and 64.5% patients respectively and in-hospital mortality was 41.9%. Whereas major complications as hypotension and cardiogenic shock occurred in 10.1% and 2.8% patients respectively and in hospital mortality was 2.8% of patients without right ventricular infarction among the inferior myocardial infarction. Multiple logistic regression analysis showed right ventricular infarction to be independent of and superior to all other clinical variables available on admission for the prediction of in hospital mortality (relative risk 88.37 percent, 95% confidence interval 7.33 to 1064.80; p=0.000) and major complications as hypotension (relative risk 394.22, 95% confidence interval 32.04 to 4849.07; p=0.000) and cardiogenic shock (relative risk 272.36, 95% confidence interval, 16.38 to 4526.35; p=0.000).Conclusion: RVMI commonly occurs in inferior myocardial infarction. It is a strong and independent predictor of major complications and in-hospital mortality. Early detection and appropriate monitoring can reduce its high mortality rate.TAJ 2013; 26: 8-13
Role of Antibiotic in Treatment of Bronchiolitis
Authors: Das HS , Hossain MA , Basak PM , Sarker BC , Saha CK , Pal BK , Jahan KI
Published: November 2018

Background: Acute bronchiolitis is a viral respiratory illness of infants and young children. It is characterized by coryzal symptoms followed by rapid onset of cough, wheeze, fever, tachypnea, chest recession and crepitation with radiological evidence of hyperinflation. Bronchiolitis occurs in first 2 years of age and is usually caused by respiratory syncytial virus. Objective: To find out the effectiveness of antibiotic in treatment of bronchiolitis.Methods: It was a randomized controlled trial carried out in Department of Paediatrics, Rajshahi Medical College Hospital, Rajshahi. 200 acute bronchiohtis patient admitted into paediatric ward of Rajshahi Medical College Hospital who fulfill inclusion criteria. Then relevant history and physical examination findings were recorded in data sheet. The even numbered patient was selected as control group and odd numbered patients as intervention group. The control group was receive supportive management and intervention group was receive lnj. Ceftriaxone 75mg/kg/day in for 5 days along with supportive management.Results: This study it was observed that bronchiolitis was more common in male. The age for peak incidence (75%) of bronchiolitis was 2-6 months. About 59% children presented with fever and all of them recovered from fever quickly before leaving hospital. At the time of admission 43% children had feeding difficulty, which improved steadily and similarly in both the groups. For days hours after admission 16% of antibiotic group and 15% of without antibiotic group had similar chest indrawing. Cough was the most common starting symptoms. None of the cases showed cyanosis and at the time of admission total 91% children had SpO2 <95%, after 4 days of admission 33%of antibiotic group and 14% of without antibiotic group still had SpO2 <95% but during discharge none of them had hypoxia. After 4 days of admission 17% of antibiotic group and 14% of without antibiotic group had crepitation and 6 days after discharge 1(1%) child of without antibiotic group and 2(2%) from antibiotic group still had crepitation. It was observed that hypertranslucency in 74% and hyperinflation in 64% in cases.Conclusion: This study shows antibiotics have no role in acute bronchiolitis management. Further multicenter study with larger sample size is recommended.TAJ 2013; 26: 43-47
Parotid Tumour Surgery- Personal Experience of 30 Cases
Authors: Islam MB , Ahmed I , Mortuza MG , Sayeed MA , Khanam K , Das Chinmoy Kanti
Published: November 2018

Parotid gland is the most common site for salivery gland neoplasm. Most of the parotid tumours are benign and are commonly pleomorphic adenoma. Parotid tumours usually present with painless slow growing lobulated masses but may be associated with pain and paresis of the facial nerve if it is malignant. However it is difficult to differentiate clinically between benign and low grade malignant tumours. We studied thirty (30) patients with parotid gland tumours during Jan/2012 to April/2016 in dept. of surgery, Rajshahi Medical College Hospital. Twenty eight (28) were pleomorphic adenoma and two (2) were mucoepidermoid carcinoma. Superficial parotidectomy done in twenty five (25) patients and total parotidectomy done in five (5) patients. In all patients facial nerve dissection and preservation were performed safely without the facilities of nerve stimulator. Two years post operative follow up was satisfactory with no residual effect. This study highlights some of the important aspects in the management of the parotid gland tumours.TAJ 2013; 26: 57-60
Perception and Practice of Hand-washing among Children in Rural Area of Rajshahi
Authors: Haque Md Jawadul , Das Chinmoy Kanti , Ara Rowsan , Amin Md Nurul , Alam Md Entekhab Ul , Begum Shahana , Rashid Md Abdur , Das Tapash Ranjan
Published: November 2018

This cross-sectional type of descriptive study was undertaken to assess the awareness and practice of hand-washing among children in three villages of Puthia Upazila, Rajshahi District, Bangladesh. A total of 1152 children aged 5 – 18 years old were purposively selected from the study area. Majority (96%) of them was students of primary or secondary grade. A few were involved in business, farming, service and others. Face to face interview was conducted with the help of a semi structured questionnaire on the variables of interest. Nearly half (49.5%) of the respondents was 11-15 years and the rest >15 years old. Male-female distribution was almost equal. Fathers of the children were service-holder (18.7%), businessman (28.6%), farmer (26.1%) and day-laborer/rickshaw puller (26.5%). Nearly 60% of respondents belonged to poor family having monthly income Taka < 10000. Majority (97.1%) of the respondents was aware of the importance of hand washing and 75% perceived that diseases could be prevented through hand washing. More than 90% of the respondents were used to using soap and water for washing hands and over 80% washed hands regularly. Over three-quarters (77.8%) were accustomed to washing hands in school before tiffin. Most (81.8%) of the respondents used sanitary latrine for defecation. The use of soap-water for washing hands after defecation was significantly higher in older children (> 12 years) than that in younger children (≤ 12 years) (p = 0.020). The use of soap water for washing hands after defecation tends to be associated with children’s grade of education with higher tendency being observed in children of secondary and higher secondary school (p < 0.001). Children belonging to higher family income were more cautious in using soap/antiseptics (p < 0.001). The study concluded that perception and practice of hand-washing is appreciably high among rural children. However, older children, children studying in secondary grade and belonged to families with higher monthly income were more cautious about hand-washing.TAJ 2013; 26: 82-91
Carcinoma of Stomach diagnosed by Trans abdominal Sonography and guided FNAC where Endoscopy was not conclusive–Three case reports.
Authors: Shah KZ , Begum N , Badruddoza SM , Ahmed P , Hossaon M
Published: November 2018

Tranabdominal sonography along with USG guided FNAC can effectively evaluate the case of gastric carcinoma; while conventional endoscopy of upper gastrointestinal tract or Barium meal X-ray may not diagnose that case coclusively. Moreover, tranabdominal sonography is comparatively more cost effective and has also no radiation effect. From this perspective, this study highlights three case reports where endoscopy of upper gastrointestinal tract could not conclude the diagnosis but tranabdominal sonography along with USG guided FNAC could delineate the condition conclusively-which were later confirmed by histopathological examination.TAJ 2013; 26: 98-102
Serum Magnesium Level among the Patients Admitted with Acute Stroke in a Tertiary care Hospital
Authors: Hossain Md Firoj , Hasan MN , Uddin SM , Masum AA , Basak PM
Published: November 2018

Magnesium deficiency was shown to trigger vasoconstriction and enhance vascular endothelial injury, thus promoting the development and progression of atherosclerosis. We hereby intended to investigate serum magnesium in the early stage of acute stroke and to evaluate the relationship between serum magnesium concentration and the development of neurological deficits. This is a descriptive type of cross sectional study was carried out in department of medicine, Comilla Medical College Hospital from June 2013 to December 2013. Fifty admitted acute stroke patients were randomly chosen for this study who fulfills inclusion criteria. The serum magnesium concentrations were measured by photometric colorimetric end point method on admission. Out of 50 acute stroke patients 30 (60%) were male and 20 (40%) were female. The mean age is 66.44 (SD ±14.8) years with male predominance. Most of the patients 30 (60%) belongs to above 60 years and 36 (72%) patients had hypomagnesaemia and 14 (28%) had normal serum magnesium level. Serum magnesium level more low in ischemic stroke (56%) . The mean serum magnesium level was 1.59 (SD ±0.37) mg/dl in all stroke patient and 1.47 (SD ±0.32) mg/dl in ischemic stroke patient was and was 1.83 (SD ±0.34) mg/dl in hemorrhagic stroke patients. Among 33 ischemic stroke patients mostly 17 (34%) patients had serum magnesium level between 1.0-1.4 mg/dl and in hemorrhagic stroke patients maximum 05 (10%) serum magnessium level was in between 1.5-1.8 mg/dl (P-value 0.0017 HS). In our study most of the patients with acute stroke were improved with marked residual disability were [19 (38.0%)], improved with minimal residual disability were [08 (16%)], improved without residual disability [04 (08%)] and death [03 (6%)] having hypomagnesaemia compared to the patients who have normal serum magnesium level with maximum improvement with minimal residual disability were [10 (20.0%)], improved without residual disability were [06 (12%)], improved with marked residual disability and death were [0 (0%)]. Gross clinical outcome disability of acute stroke patients was worse who had hypomagnesaemia (P-value 0.001 significant). Magnesium levels are significantly decreased in acute stroke; both in ischemic stroke patients as well as in patients of hemorrhagic. Patients with low serum magnesium level in acute stroke associated with worse clinical outcome.TAJ 2014; 27(1): 50-56