bluuebunny/crossref_metadata_2025 huggingface dataset:
SYSTEMATIC MAPPING STUDY: ANALISIS MANAJEMEN PERUBAHAN PADA PERUSAHAAN KELUARGA
Authors: Alfatiha Raja Ainaya
Published: July 2022

Penelitian ini bertujuan untuk melakukan pemetaan penelitian dengan topik pembahasan manajemen perubahan (change management) pada  perusahaan keluarga (family business). Penelitian ini meliputi pembahasan tentang fokus penelitian, metode dan tipe penelitian, dan tren publikasi berdasarkan Negara dan waktu. Penelitian ini menggunakan metode penelitian kualitatif menggunakan Systematic Mapping Study (SMS) untuk melihat perkembangan penelitian. Pencarian data menggunakan database scopus dan science direct dengan hasil 29 artikel. Berdasarkan hasil pemetaan menunjukkan bahwa fokus penelitian yang paling sering dibahas adalah corporate governance, entrepreneurial, firm capability, dan organizational development. Metode penelitian yang banyak digunakan adalah kualitatif yaitu 20 artikel (69.0%). Paper type yang dominan digunakan adalah kategori evaluation research yaitu 14 artikel (48.3%). Tren publikasi negara yang banyak melakukan penelitian adalah Italy yaitu 4 artikel (13.8%) dan puncak publikasi berada di tahun 2021 dengan jumlah 7 artikel (24.1%). Sehingga hasil dari penelitian ini dapat memberikan gambaran dan peluang dalam mengeksplorasi topik penelitian baru terkait manajemen perubahan dan perusahaan keluarga
MENGAJAR EKONOMI MIKRO BERBASIS WIRAUSAHA EKONOMI KERAKYATAN DAN LOCAL WISDOM: BAGAIMANA?
Authors: Prakoso Albrian Fiky , Haryono Agung , Hermanto Febrika Yogie
Published: July 2022

Pembelajaran ekonomi mikro di perguruan tinggi menjadi mata kuliah yang sulit bagi sebagian besar mahasiswa di Indonesia. Rendahnya pemahaman mata kuliah ekonomi mikro ini juga menjadikan mahasiswa tidak menyukainya. Banyak upaya telah dilakukan untuk membuat pembelajaran ekonomi mikro menjadi lebih menarik, namun tidak mudah melakukannya. Penelitian ini mencoba menawarkan cara mengajarkan ekonomi mikro di perguruan tinggi dengan mengaitkan perwujudan wirausaha ekonomi kerakyatan dan local wisdom yang ada di Indonesia agar lebih menarik bagi mahasiswa. Jenis penelitian ini termasuk dalam jenis penelitian litelature review. Populasi terdiri dari 24 artikel yang terbit di jurnal internasional. Sampel diambil secara purposive. Terpilih 5 artikel yang diambil berdasarkan materi yang dibahas dalam perkuliahan yaitu teori harga dan struktur pasar. Hasil yang didapatkan berdasarkan artikel yang dirujuk adalah mengajar ekonomi agar lebih menarik dan mudah diterima oleh siswa dengan mengaitkan kehidupan mahasiswa sehari-hari. Implikasi terpentingnya yaitu mahasiswa tidak salah lagi dalam menebak kurva permintaan karena telah dikaitkan dengan budaya Indonesia jika meminta suatu barang dengan tangan kanan.
Sistem Pemantau Kualitas Udara Bebasis Wireless NetworkK
Authors: Juwito Arif Febriansyah , Sanjaya Aji , Atabiq Fauzun , Putra Irwanto Zarma , Gozali M. Syafei , Eko M. Prihadi , Toar Handri , Fitriyah Qoriatul , Hasnira Hasnira
Published: July 2022

Sistem pemantau kuliatitas udara via web berbasis wireless network didesign sebagai sebuah jaringan telekomunikasi yang terkait secara nirkabel. Untuk mengetahui nilai dari kualitas udara di suatu wilayah yang ditetapkan secara real, maka perlu membangun sebuah sistem pemantauan kualitas udara. Pada penelitian ini akan digambarkan suatu rancang bangun dari sistem pemantau kualitas udara dengan memanfaatkan arduino yang dapat di akses melalui website. Perangkat ini dirancang dengan menggunakan arduino, sensor MQ7, hosting apache offline dan perangkat Wi-Fi ESP8266. Implementasi dari pengoperasian perangakat arduino yang digabungkan dengan ESP8266 ini dimaksudkan untuk memberikan pengaturan dalam mengatasi masalah pengumpulan data ataupun pemantauan kondisi lingkungan yang sulit dijangkau, dengan perangkat yang portable dengan sistemyang lebih dinamis, dan dapat diakses melalui website sehingga dapat mengakses infromasi data pembacaan sensor dari jarak jauh secara real.
Data Classification and Access Control in Indonesia One Map Policy Geoportal
Authors: Purwanto Bayu
Published: July 2022

Indonesia has a data access policy on one map policy geoportal. Users at each level of government have different access rights to data. The President has full rights to view and downloads the data, while the governor or regent can only see certain attributes and download only its region on the same data. Data in one map policy geoportal must be able to facilitate the differences in access rights. The one map policy geoportal uses a service query system to facilitate the classification of access to process view data. In the process of downloading data geoportal using database queries. The choice of download data through the database is based on the results of the test download data from the database and service. These results indicate that downloading data through the database is faster than downloading data through a service.
Application of Generalized Additive Model for Identification of Potential Fishing Zones Using Aqua and Terra MODIS Imagery Data
Authors: Sasmito Bandi , Bashit Nurhadi , Arinda Bella Riskyta , Sukmono Abdi
Published: July 2022

Remote sensing applications can provide information on oceanographic conditions for identification of potential fishing zones by combining statistical approaches. Determination of fish catch zones needs to be studied on the relationship between oceanographic parameters and fish catches to improve the efficiency and effectiveness of fishing operations by fishermen. Based on this, identification of potential fishing zones needs to examine the relationship between fish catches and oceanographic parameters using the Generalized Additive Model (GAM) in the Java Sea. GAM analysis was carried out using fish catch data as response variables and oceanographic parameters such as sea surface temperature (SST) and chlorophyll-a image processing results from MODIS, SSS from CMES, and Depth data as predictor variables. The selection of the best model is determined by the highest percentage of CDE and the lowest AIC. GAM modeling results show that 60.3% of fish catches in the Java Sea are influenced by oceanographic factors and 39.7% by other factors. The oceanographic parameter that has the most influence on fish catches is the concentration of chlorophyll-a. GAM modeling results show that fish in the Java Sea tend to be found in sea that have chlorophyll-a concentrations of 0.2 mg/m3 – 0.5 mg/m3, SST 280C – 310C, salinity 31.8 PSU – 33 PSU, and a depth of 20 m. – 50 meters. Potential fishing zones were identified based on the results of the GAM modeling analysis. Potential fishing zones in the Java Sea from March 2021 to June 2021 have varying spatial distributions. The results of the most fishing potential zones were found on June 3, 2021, which were distributed the most in the sea around Pulau Laut, in the southern part of the island of Borneo, and the north on the island of Madura.
Mengukur Akuntabilitas Dana Bantuan Operasional Sekolah
Authors: Sopian Sopian , Asqolani Asqolani
Published: July 2022

Penyelenggaraan pendidikan dasar merupakan kewajiban pemerintah untuk mencerdaskan kehidupan bangsa. Kewajiban tersebut diwujudkan dalam bentuk penyediaan dana pendidikan melalui bantuan operasional sekolah (BOS) kepada semua sekolah tingkat SD dan SMP. Untuk mencegah penyalahgunaan dana BOS diperlukan keterbukaan dan akuntabilitas. Riset ini bertujuan menguji pengaruh kompetensi, fungsi manajemen sekolah dan teknologi informasi terhadap akuntabilitas  pengelolaan dana BOS. Pengujian pengaruh didasari oleh teori strewardship, teori stakeholders dan teori legitimasi. Riset ini menggunakan metode kuantitatif dengan alat bantu analisis Partial Least Squares Structural Equation Modelling (PLS SEM). Hasil penelitian menyimpulkan bahwa kompetensi, fungsi manajemen sekolah dan teknologi informasi baik secara partial maupun secara simultan mempengaruhi secara signifikan akuntabilitas pengelolaan dana BOS. Hasil riset ini dapat dipergunakan oleh Dinas Pendidikan Kota Tangerang Selatan untuk memperkuat kompetensi bendahara sekolah, meningkatkan partisipasi manajemen sekolah dan masyarakat serta mengoptimalkan penggunaan teknologi informasi untuk mendukung pengelolaan dana BOS yang transparan dan akuntabel.

 

Kata kunci: Akuntabilitas, Dana BOS, Kompetensi, Manajemen Sekolah, Teknologi Informasi
Anthropometric and Physical Data of Children in Football
Authors: Martiri Altin
Published: July 2022

Football is one of the most played and complex sports in the world, where players need technical, tactical and physical skills to succeed. Although its popularity compares to other sports at any age level, there is a lack of information on the technical, physiological and conditioning aspects of children players. Therefore, the purpose of this study was to investigate the physical, muscular performance and speed of 12-year-old football players. Eighty-two footballers who were actively participating in the Albanian Children’s Championship participated in the study. Batteries for fitness testing: Standard height, body weight and calculated body mass index (BMI), speed (30m sprint), vertical jump, and rated lower body muscle strength (vertical jump) were the tests selected for to measure. Data were subjected to statistical analysis using the ANOVA method. Identifying the physical and physiological characteristics of football players provides insight into the physical and physiological qualities that are important to becoming a team member and playing successfully. The most important issue for the coach and football player is to determine the improvement of physical fitness through a well-modeled training programmer. Although anthropometric and physiological profiling is best seen as an objective tool for monitoring young player, physiological data may not be the only predictor of competitive success in football. On the other side, heritage in related physiological standards is an important prerequisite for success in football. Physiological standards play a crucial role in the selection of football talent.
Hydration and Physical Activity
Authors: Knap Bojan
Published: July 2022

The importance of water homeostasis is extremely important. Maintaining hydration, the state of preserving body water within its optimal homeostatic range, is essential to sustain life. Water is an essential nutrient and contributes 50-70% of total body mass. An assessment of hydration during physical activity can prevent dehydration, which impairs physical and cognitive performance. A 2% body mass loss is a recognized threshold beyond which exercise dehydration impairs exercise performance. Liquid needs for recreational sports and physical activity are individual and are rarely higher than 500ml of hypotonic fluid per hour. If fluid requirements are low, concentrated sports drinks (providing energy intake) can help sustain exercise performance. Overhydration could be dangerous and can result in hyponatremia. Individual evaluation of water needs is important. In warm environmental conditions, an individual nutrition and hydration plan is crucial for the health and optimal performance and using existing recommendations in clinical sports nutrition to prevent over - and dehydration.
Status of the Exercise Habits for Health in Turkish Population: A General Review of the Turkish National Publications
Authors: Subak Erdem 
Published: July 2022

The number of studies on the positive effects of exercise on health is increasing day by day. The data show that 31.1% of adults in the world’s population are physically inactive. It has been shown that 51.6% of the American population meet aerobic activity suggestions, 29.3% fulfill muscle-strengthening recommendations and 20.6% meet both. In Turkey, many types of research related to this field have been published in national publications. This study aims to compile research on exercise and health, published in national journals in Turkey. Thus, this study will provide an overview of studies on health and exercise in Turkey. Besides, in this study, the levels of exercise habits of people living, working, or studying in various cities of Turkey have been reviewed.
INCLUSÃO ESCOLAR: UM ESTUDO DO PROCESSO DE ATENÇÃO PROFISSIONAL PARA CRIANÇAS COM DIFICULDADE DE APRENDIZAGEM NO ENSINO FUNDAMENTAL I DE UMA ESCOLA DO MUNICÍPIO DE SÃO PAULO
Authors: DE OLIVEIRA CLÁUDIA MARIA DE OLIVEIRA
Published: July 2022

Esta pesquisa insere – se no eixo temático educação inclusiva e equipe multidisciplinar relacionados ao processo de atenção profissional no ambiente educacional da criança com dificuldade de aprendizagem. Objetivo desta pesquisa é analisar as concepções, tensões, conflitos e perspectivas no processo de inclusão escolar por meio de uma equipe especializada no município de São Paulo visando os efeitos do trabalho entre a clínica e a escola. Este estudo baseou-se em uma pesquisa com professores, pais e profissionais da saúde de crianças encaminhadas pelas escolas que solicitavam auxilio no processo de inclusão escolar. O método utilizado foi um estudo descritivo e qualitativo com enfoque epistemológico interpretativo com questionário e análise documental. Foram entrevistadas 12 pessoas, sendo pais, profissionais da área da saúde e professores que acompanhavam 4 crianças com dificuldades de aprendizagem e estavam inseridas no processo de inclusão escolar de uma escola no município de São Paulo. Os resultados obtidos mostram que os profissionais de apoio são apontados como alternativas favoráveis ao processo de inclusão tendo em vista que a junção da saúde e educação oferece maiores oportunidades educacionais para os alunos por meio de um trabalho coletivo. Percebe- se que os profissionais em equipe multidisciplinar são apontados como alternativas favoráveis ao processo de inclusão tendo em vista a junção da saúde e educação oferecendo maiores oportunidades educacionais para todos os alunos. Conclui- se que a atuação de uma equipe multidisciplinar em clínicas por meio de parceria pode contribuir para a construção de escolas mais inclusivas.
Induction of Labor According to Medical Indications: A Critical Evaluation through a Prospective Study
Authors: Monari Francesca , Pellegrini Rosamaria , Menichini Daniela , Spelta Eleonora , Tarozzi Giulia , Grandi Giovanni , Facchinetti Fabio
Published: July 2022

Background: The induction of labor (IOL) is a common obstetric intervention, steadily increasing (one out four pregnancies) in the last years. This procedure should be considered only when there is a medical indication, and when the benefits outweigh the maternal and/or fetal risks of waiting for spontaneous onset of labor. Therefore, this study aims to compare the efficacy of the IOL in terms of induction to delivery time, mode of delivery, and neonatal well-being among different evidence-based and non-evidence-based indications. Methods: This prospective study was conducted at the University Hospital of Modena, between January and December 2020. We included singleton pregnant women undergoing IOL, at the term. Intrauterine deaths, small for gestational age fetuses <5th centile as well women with hypertensive disorders were excluded. Women have been subdivided into 3 groups based on the indication to IOL: premature rupture of membranes (PROM), post-date pregnancy (>41 weeks + 3 days), and non-evidence-based indications (NEBI). The primary outcome is the time occurring between IOL and delivery (TIME), analyzing separately by parity. Moreover, mode of delivery and neonatal well-being were evaluated. Results: A total of 585 women underwent IOL in the study period. Overall, the median TIME between IOL and delivery was 19 hours, and the mean cesarean section CS rate was 15.5% (91/585). Pregnancies induced for postdate and non-evidence-based indications registered respectively a significantly higher mean time (p< 0.001), compared with women induced for PROM. This occurred both in nulliparous and multiparous women. Moreover, at multivariate analysis, the IOL TIME ≥24 hours was significantly influenced by Bishop score (p = 0.000) and NEBI (p = 0.02) in nulliparous and by gestational age (p = 0.000) and NEBI (p = 0.02) in multiparous. Moreover, CS rate was significantly influenced by Bishop score (p = 0.003) in nulliparous and by gestational age (p = 0.01) in multiparous. Finally, neonatal intensive care unit (NICU) admission resulted significantly influenced only by gestational age (p = 0.002) in multiparous. Conclusions: Our study confirms that IOL in non-evidence-based indications, leads to an increase in induction to delivery time comparing with women induced for PROM, both in nulliparous and multiparous women, thus it should be justified and carefully evaluated. Further randomized controlled trials (RCT) conducted in European/Italian settings are needed to determine the perinatal outcomes of IOL in non-evidence-based indications.
Safety and Appropriateness in the Management of the Treatment Pathway of Pregnant Women with Gestational Diabetes
Authors: Fornasier Giulia , Candido Riccardo , Zamagni Giulia , Trojniak Marta Paulina , Brunato Barbara , Specogna Erika , Agus Sandra , Rossi Paola , Arbo Anna
Published: July 2022

Gestational diabetes (GDM) is quite common during pregnancy, and its prevalence is rising because of the increased overweight and obesity rates. In patients with GDM, proper glycemic control, adherence to a suitable diet and antidiabetic treatments can reduce the likelihood of maternal-neonatal complications. For this reason, this study aims to assess the therapy adherence of pregnant women with GDM. Treatment adherence was assessed by both glucometer and diabetologist’s analysis reported in the electronic medical record. Cohen’s Kappa was used to assess the agreement between the two classifications. Moreover, a multivariate logistic regression analysis was performed to identify potential risk factors for non-adherence to treatment. Overall, 287 patients were enrolled, and 271 were available for follow-up. Low concordance between the glucometer and the diabetologist’s analysis was found, mainly due to the complexity of patients with GDM. Indeed, 46% of patients were classified as not adherent due to glucometer results and 42% based on medical assessment. This study highlights the importance of monitoring patients with gestational diabetes to assess and increase adherence to therapy properly.
Efficacy of Intermittent Theta-Burst Stimulation and Transcranial Direct Current Stimulation in Treatment of Post-Stroke Cognitive Impairment
Authors: Chu Minmin , Zhang Youmei , Chen Jianer , Chen Weihai , Hong Zhenmei , Zhang Yue , Yu Hong , Zhang Feilan , Ye Xiancong , Li Jingjing , Yang Yun
Published: July 2022

Background: The efficacy of intermittent theta-burst stimulation (iTBS) and transcranial direct current stimulation (tDCS) combined with cognitive training in the treatment of post-stroke cognitive impairment (PSCI) requires further investigation. Methods: We randomly assigned 60 patients with PSCI to receive iTBS (n = 21), tDCS (n = 19), or cognitive training alone (n = 20). Cognitive function was evaluated by the Loewenstein Occupational Therapy Cognitive Assessment (LOTCA), and the performance of activities of daily living (ADL) was assessed with the modified Barthel Index (MBI). Of these patients, 14 participated in the functional near-infrared spectroscopy (fNIRS) measurement. Results: After six weeks of treatment, cognitive function improved in all three groups of PSCI patients. Compared with patients receiving only cognitive training, the cognitive function of patients in the iTBS combined with cognitive training (p = 0.003) and tDCS combined with cognitive training groups (p = 0.006) showed greater improvement. The cognitive improvement from tDCS was related to the activation of the frontopolar cortex (FPC), while the improvement of cognition by iTBS was based on the activation of the stimulation site (the dorsolateral prefrontal cortex) and some distant regions. Conclusions: Both iTBS and tDCS in addition to cognitive training appear to improve cognitive function and quality of life of patients with PSCI, compared to cognitive training alone. tDCS improved cognitive function by improving the patient’s valuation, motivation, and decision-making substructures, while iTBS improved patients’ assessment and decision-making abilities, improving cognitive control and, ultimately, overall cognitive function.
Outlines to Initiate Epilepsy Surgery in Low- and Middle-Income Countries
Authors: Bäuerle Peter , Schneider Ulf , Holtkamp Martin , Gloveli Tengis , Dugladze Tamar
Published: July 2022

Surgery is an essential treatment option for patients with drug-resistant epilepsy. While most epilepsy patients worldwide live in low- and middle-income countries (LMIC), most of these countries do not have epilepsy surgery, and those that do have surgical epilepsy services lack capacities. The rapidly growing population in LMIC further widens the gap between the number of patients who can potentially benefit from surgery and those who can actually receive it. This makes the initiation of new surgical epilepsy centers in those countries an urgent issue. Epilepsy surgery is feasible in LMIC, even in resource-poor settings, but lack of local expertise is a major obstacle to the introduction of new surgical services. Importantly, expertise deficits can be compensated by collaborating with a well-established epilepsy center for knowledge transfer, skill building and mentoring. Such projects need to be organized in a multidisciplinary team, should focus on the given circumstances, and should use technologies and personnel that are reasonably available and can function sustainably. Local cultural factors and improvement of patients’ quality of life are further spotlights reflected by an increasing number of studies. As a general outline for a new surgical epilepsy program in LMIC, it is recommended to initially focus on patients with mesial temporal lobe epilepsy due to hippocampal sclerosis or other well defined pathologies. These constellations have an excellent surgical outcome in terms of seizure control, can be diagnosed by non-invasive methods, and can be reliably identified even under low-resource conditions. Moreover, surgery can be performed with a highly standardized approach and at reasonable costs, and the vast majority of patients will benefit from surgical intervention. The range of services can then be gradually expanded, depending on growing expertise, local needs, prospects and constraints. Although the introduction of surgical epilepsy services in LMIC can face several challenges, none of them should be a permanent barrier for further establishments.
Sleep Deprivation Increases the Anesthetic Potency of Sevoflurane Regardless of Duration
Authors: Qian Hao , Zhou Qiao , Cui Nanxue , Zhang Shihai
Published: July 2022

Background: Sleep deprivation reduced the time to induce anesthesia by propofol and isoflurane and prolonged the time to recovery. However, it is unknown whether sleep deprivation affects the potency of inhaled anesthetics. In this study, the effect of sleep deprivation on sevoflurane anesthetic potency was explored. Methods: Ten animals received the following behavioral interventions in turn (ad libitum activity, 24 h sleep deprivation, 48 h sleep deprivation, 72 h sleep deprivation). After each behavioral intervention, the 50% effective dose for loss of righting reflex (LORR ED50) was determined to evaluate the potency of sevoflurane in inducing unconsciousness in mice. Repeated-measures analysis of variance was used to compare our behavioral interventions statistically, post hoc multiple comparisons were made using the Bonferroni test. Results: Sleep deprivation decreased the sevoflurane LORR ED50 significantly (p = 0.0003). However, the effect of duration of sleep deprivation on LORR ED50 was not statistically significant (p > 0.9999). Conclusions: Sleep deprivation can increase the anesthetic potency of sevoflurane regardless of duration of sleep deprivation.
Current Prostheses for Transcatheter Heart Valve Replacement: A Technical and Clinical Review
Authors: Rudziński Piotr Nikodem , Mach Markus , Gross Christoph , Russo Marco , Werner Paul , Coti Iuliana , Scherzer Sabine , Andreas Martin
Published: July 2022

Transcatheter aortic valve replacement (TAVR) has become a cornerstone in today’s treatment of aortic stenosis. Modern transcatheter prostheses are continuously evolving and each one features different design traits. In this review, the authors provide insight in the technical differences of current prostheses and TAVR related clinical decision pathways, preferably useful for the beginners but also for advanced operators. Additionally, procedural considerations and comparative outcomes of the prostheses are discussed. In doing so, the authors aim to facilitate the choice of the ideal transcatheter valve procedure for each individual.
The Use of a Handheld Ultrasound Device to Guide the Axillary Vein Access during Pacemaker and Cardioverter-Defibrillator Implantation. A Feasibility Study
Authors: Sassone Biagio , Simeti Giuseppe , Virzì Santo , Pasanisi Giovanni , Muser Daniele
Published: July 2022

Background: Although ultrasound guidance for axillary vein (AV) access (USGAVA) has been described as a reliable technique for cardiac implantable electronic device (CIED) implantation, no data is available on the use of handheld ultrasound devices (HUD) in such a setting. Objective: We investigated the feasibility of using a HUD for USGAVA in patients referred to our Institution for CIED implantation. Methods: The procedure details of 80 consecutive patients undergoing USGAVA (Group-1) from June 2020 to June 2021 were prospectively collected and compared to those of an age and sex-matched cohort of 91 patients (Group-2) who had undergone AV access with the traditional venipuncture guided by fluoroscopic landmarks. Results: The two groups were comparable for the success rate of venous access (92.5% versus 93.4%, p = 0.82), complication rate (1.3% versus 0.9%, p = 1.0), and procedure time (71 ± 32 min versus 70 ± 29 min, p = 0.9). However, Group-2 had a longer X-ray exposure time (7.6 ± 8.4 min versus 5.7 ± 7.3 min, p = 0.03). In Group-1, the univariate logistic regression analysis demonstrated that the AV diameter was associated with successful USGAVA (odds ratio = 3.34, 95% confidence interval 1.47–7.59, p < 0.01), with a 3-fold increase of probability of success per each 1 mm increase in the AV diameter. Conclusions: USGAVA using a HUD for CIED implantation is a feasible, effective, and safe technique; moreover, it saves X-ray exposure time without lengthening the implant procedure time.
The state of health as a factor affecting the work activity of working elderly people
Authors: Anishchenko Elena B. , Trankovskaya Lidiya V. , Vazhenina Antonina A. , Tarasenko Galina A.
Published: July 2022

Currently, there is an increase in the number of elderly residents in the world community. The researchers note the progressive aging of the working population long with the existing unfavorable demographic trends and a number of socio-economic changes. Thus, many countries have made a push to increase the level of employment among people of the "third age". In addition, many states have raised the official retirement age for both men and women. However, economic measures, primarily raising the official retirement age, will be successful only if employees are able to perform labor functions productively and maintain their physical and mental health at the stage before retirement. The analytical review presents an analysis of modern foreign and domestic literature, where scientists publish works devoted to the study of the degree of influence of health indicators on the labor activity of working elderly people. Scientists have identified the main factors affecting the performance of an elderly person with the help of studies conducted in different countries. At the same time, the elderly have an increase in acute and(or) chronic diseases, which adversely affects their level of performance. Whereas physical and social activity significantly contributes to reducing the incidence of persons of the "third age".
Life expectancy of coal miners with an established diagnosis of occupational diseases
Authors: Tikhonova Galina I. , Piktushanskaya Tatyana E. , Gorchakova Tatyana Yu. , Serebryakov Pavel V.
Published: July 2022

Introduction. It is known that workers employed in harmful and dangerous working conditions initially have better health characteristics compared to the population as a result of medical and professional selection. Harmful production factors cause significant damage to health and can lead to the formation of occupational diseases. Preventive medical and rehabilitation care for patients with occupational pathology, combined with social and economic support measures, contributes to maintaining health and increasing life expectancy. It is important to understand how medical and social assistance to patients compensates for the damage caused to the health of workers by harmful working conditions. The study aims to compare the life expectancy of coal miners with an established diagnosis of occupational disease (OD) and the male population of the same region. Materials and methods. The researchers formed a cohort of coal miners in the Rostov region based on the materials of the database of the State Medical Institution of the Rostov region "Medical and Rehabilitation Center No. 2". All surveyed coal miners have established occupational diseases in different years. The observation period was 26 years from 01.01.1990 to 31.12.2015. Of the total cohort at the end of the observation period, 1,898 people were alive, 8082 people died. The experts examined the working conditions of miners, the average age of registration of the OD, depending on the nosological form. The researchers have conducted a comparative assessment of their life expectancy and the life expectancy of the male population of the same region, calculated from mortality tables. Results. The calculation of the average life expectancy of miners showed that its value in subgroups with different forms of OD differed significantly depending on the diagnosis: from 58.7 to 68.2 years. A comparative analysis of the life expectancy of coal miners with an established diagnosis of OD and in population control revealed a lower life expectancy of miners. The smallest differences in life expectancy we have noted in those miners who have a diagnosis of pneumoconiosis. Their life compared to the men of the Rostov region was shorter by less than a year. At the same time, miners with a diagnosis of occupational bronchitis lived 5.3 years less and with a diagnosis of vibration disease - 4.8 years compared to the population control. Conclusion. The study showed that coal miners diagnosed with occupational diseases have a lower average life expectancy than in the population, despite the "healthy worker effect", which we have as a result of medical selection and self-selection of persons to work in contact with harmful production factors. The lower life expectancy of workers with a diagnosis of occupational diseases we trace both in total for all diseases, and for individual forms of OD. Ethics. The authors have conducted the study in compliance with Ethical standards.
Physiological Response and Physical Quality of Cihateup Duck Meat Given Natural Isotonic in Dry Maintenance System
Authors: Frasiska N. , Riyadi R. A. , Rahayu N.
Published: July 2022

This study aims to determine the effect of giving natural isotonic and determine which level is the most optimal for the physiological response and physical quality of Cihateup Duck meat. This study used an in vivo experimental method and a completely randomized design (CRD) with a treatment consisting of 4 treatments and 5 replications. The remedies in this study were the addition of celery extract as much as 25 mg, 50 mg, and 75 mg, as well as lime juice as much as 2%, 3%, and 4%. The results based on analysis of variance showed that the treatment had a significant effect on the pH value of the meat (P<0.05), but did not affect heart rate, rectal temperature, and cooking loss (P>0.05). The addition of 25mg celery extract and 2% lime juice is the optimal level.
Effects of the use of Fermented Gamal Leaf Flour as a Concentrate Substitute on Performance of the Landrace Breeding Pigs
Authors: Nguru D. A. , Telupere F. M. S. , Wielawa E. D.
Published: July 2022

This study aimed to evaluate the effect of fermented gamal leaf flour as a substitute for concentrate in the basal ration on the performance of landrace crossbreed pigs. The materials used in this study were 16 landrace crossbred male pigs at the starter phase aged 1–2 months, with an average of 7.56 kg and KV of 40.68%. The design was a randomized block design with four treatments and four replications. The treatments were R0: basal ration + 100 concentrate without fermented gamal leaf meal (FGLF), R1: basal ration + 90% concentrate + FGLF 10%, R2: basal ration + 80% concentrate + FGLF 20%, R3: basal ration + 70% concentrate + 30% FGLF. The results of variance showed that the use of fermented gamal leaf flour (FGLF) as a substitute for concentrate in the basal ration of landrace crossbreed pigs had no significant effect (P>0.05) on performance. This study concluded that using fermented gamal leaf flour as a substitute for concentrate in basal rations in landrace crossbreed pigs gave relatively the same results up to 30%.
Management of St. Croix Sheep and Garut Sheep Genetic Resources in Sheep Formation
Authors: Adiati U. , Rusdiana S.
Published: July 2022

This study aimed to determine the management of the genetic resources of St. Croix sheep and Garut sheep in the formation of sheep clumps and their physiological conditions. The study was conducted at the Livestock Research Institute on Jalan Raya Pajajaran Bogor, West Java, in 2019. Ex-situ collection materials and characterization of St. Croix sheep and Garut sheep were as many as 250 heads; sheep breeding was carried out in groups; one male married 5-10 heads. The rams were left in the mating group for two oestrus cycles (34 days). Primary data and secondary data were analyzed descriptively and quantitatively. The results were obtained in the germplasm research of St. Croix with an average mating body weight of 23.45 ± 4.08 kg and Garut sheep of 26.20 ±  4.92 kg. The average birth weight of St. Croix sheep was 2.26+0.35 kg, and Garut sheep was 2.05± 0.47kg. The establishment of the St. Croix and Garut sheep have high genetic quality, production, and reproductive characteristics, but each has a different productivity level. The study of germplasm preservation of sheep was carried out to increase the population of St. Croix sheep and pure Garut sheep so that the maximum target population of >200 sheep was achieved to meet the demand for seeds as animal food.
Basic principles and applications of animal cell culture in pharmaceutical sciences
Authors: Srisongkram Tarapong
Published: July 2022

Animal cell cultures are very large fields of research with bringing up various opportunities for novel drug discoveries. Most biologic analogs (i.e., biologics drugs, vaccines especially inactivated vaccines, or subunit vaccines, monoclonal antibodies, and recombinant proteins) are manufactured by using animal cell culture techniques. Thus, in this paper, the basic principle and applications of animal cell cultures are reviewed for the next-generation pharmacists to keep up with today's innovations in drug discoveries and healthcare perspectives. This paper covered 4 basic types of animal cell cultures (i.e., organ culture, primary cell culture, cell lines, organotypic cell culture), and their applications in the pharmaceuticals industries. Moreover, this paper covered the uses of three-dimensional cell cultures in the therapeutic approach as well.
Differential expression of KCTD15 in cancers of the breast.
Authors: Mamoor Shahan
Published: July 2022

Breast cancer affects women at relatively high frequency (1). We mined published microarray datasets (2, 3) to determine in an unbiased fashion and at the level of the transcriptome genes most differentially expressed in the primary tumors of patients with early-onset breast cancer. We found significant differential expression of the gene encoding potassium channel tetramerization domain-containing 15, KCTD15, when comparing primary tumors of the breast to the tissue of origin, the normal breast: in women aged 45 and younger, and women aged 70 and higher. KCTD15 was also differentially expressed in the brain metastases of patients with brain metastatic breast cancer. KCTD15 mRNA was present at significantly higher quantities in tumors of the breast as compared to normal breast tissue. Analysis of human survival data revealed that expression of KCTD15 in primary tumors of the breast was correlated with overall survival in patients with basal, luminal B and HER2+ subtype breast cancer, demonstrating a relationship between primary tumor expression of a differentially expressed gene and patient survival outcomes influenced by PAM50 molecular subtype. KCTD15 may be of relevance to initiation, maintenance or progression of cancers of the female breast.
Perilaku Keausan Karet Ban Komersial terhadap Baja Ringan dalam Kering, Basah, dan 3,5% NaCl Lingkungan Korosif
Authors: Maulana Zidhan Akbar
Published: July 2022

Kinerja tribologi dari karet ban yang digunakan secara komersial dievaluasi pada kondisi ambien di bawah lingkungan korosif kering, basah, dan 3,5% NaCl. Alat pin-on-disc digunakan untuk percobaan. Beban yang diterapkan 2.5N pada kecepatan geser 0,246 ms-1 jarak mulai dari 75m-2650m adalah digunakan untuk penelitian ini [1]. Untuk keausan poligonal ban truk / bus dan mobil dan menjelaskan mekanisme generasi keausan poligonal yang disebabkan oleh mode getaran alami pertama ban dalam arah vertikal[2]. sifat mekanik dan studi morfologi untuk meningkatkan kinerja mekanik barang karet [3]. Metode yang digunakan adalah Penyerapan air menginduksi sifat tribologi yang lebih baik dengan mengubah sifat permukaan tribopair[4]
Monte-Carlo Policy-Tree Decision Making
Authors: Haggenmiller Acshi , Olson Edwin
Published: July 2022

In this paper, we propose Monte-Carlo Policy-Tree Decision Making (MCPTDM), an uncertainty-aware framework for high-variance planning problems with multiple dynamic agents. Planning when surrounded by multiple uncertain dynamic agents is hard because we cannot be certain of either the initial states or the future actions of those agents, leading to an exponential explosion in possible futures. Many important real-world problems, such as autonomous driving, fit this model. To address these difficulties, we combine Multi-policy Decision Making (MPDM) and Monte Carlo tree search (MCTS) and perform policy tree search with marginal action cost (MAC) estimation and repeated belief particles. We first design a synthetic experiment to evaluate these novel improvements in isolation. Then we evaluate the complete framework in a self-driving car simulation experiment and compare it against MPDM and Efficient Uncertainty-aware Decision Making (EUDM) methods. We release our complete source code for replicating our experiments and results.
Differential expression of cullin 9 in cancers of the breast.
Authors: Mamoor Shahan
Published: July 2022

Breast cancer affects women at relatively high frequency (1). We mined published microarray datasets (2, 3) to determine in an unbiased fashion and at the level of the transcriptome genes most differentially expressed in the primary tumors of patients with early-onset breast cancer. We found significant differential expression of the gene encoding cullin 9, CUL9, when comparing primary tumors of the breast to the tissue of origin, the normal breast: in women aged 45 and younger, and women aged 70 and higher. CUL9 was also differentially expressed in the brain metastases of patients with brain metastatic breast cancer. CUL9 mRNA was present at significantly higher quantities in tumors of the breast as compared to normal breast tissue. Analysis of human survival data revealed that expression of CUL9 in primary tumors of the breast was correlated with recurrence-free survival in patients with basal, luminal B, HER2+ and normal-like subtype breast cancer, demonstrating a relationship between primary tumor expression of a differentially expressed gene and patient survival outcomes influenced by PAM50 molecular subtype. CUL9 may be of relevance to initiation, maintenance or progression of cancers of the female breast.
Concomitant and productive genital infections by HSV-2 and HPV in two young women: a case report
Authors: Uysal Ilkay Basak , Boue Vanina , Murall Carmen Lia , Graf Christelle , Selinger Christian , Hirtz Christophe , Bernat Claire , Ravel Jacques , Reynes Jacques , Bonneau Marine , Rahmoun Massilva , Segondy Michel , Boulle Nathalie , Grasset Sophie , Groc Soraya , Waterboer Tim , Tribout Vincent , Bravo Ignacio G , Burrel Sonia , Foulongne Vincent , Alizon Samuel , Tessandier Nicolas
Published: July 2022

Human papillomaviruses (HPVs), the most oncogenic virus known to humans, are often associated with Herpes Simplex Virus-2 (HSV-2) infections. The involvement of the latter in cervical cancer is controversial but its long-term infections might modulate the mucosal microenvironment in a way that favors carcinogenesis. We know little about coinfections between HSV-2 and HPVs, and studying the immunological and microbiological dynamics in the early stages of these infections may help identify or rule out potential interactions. We report two cases of concomitant productive, although asymptomatic, HSV-2 and HPV infections in young women (aged 20 and 25). The women were followed up for approximately a year, with clinical visits every two months and weekly self-samples. We performed quantitative analyses of their HSV-2 and HPV viral loads, immunological responses (IgG and IgM antibodies and local cytokines expression profiles), vaginal microbiota composition, as well as demographic and behavior data. We detect interactions between virus loads, immune response, and the vaginal microbiota, which improve our understanding of HSV-2 and HPVs' coinfections and calls for further investigation with larger cohorts.
KEBERMANFAATAN TEKNOLOGI SISTEM INFORMASI PADA DUNIA PENDIDIKAN DI INDONESIA
Authors: Tarigan Rangga Satya
Published: July 2022

Pemanfaatan Teknologi informasi dan Komunikasi (TIK) di bidang layananadministrasi akademik pada perguruan tinggi menjadi suatu kebutuhan, bukan hanyasekedar martabat atau lifestyle manajemen pendidikan tinggi terkini. tetapi padaimplementasi-nya, banyak hambatan yang ditemui perguruan tinggi dalam menerapkanTIK dalam proses pengelolaan kelembagaan ini baik faktor teknis juga non teknis Penguatan tata kelola, akuntabilitas serta gambaran publik forum pendidikantinggi akan bermuara pada meningkatnya kinerja lembaga pendidikan tinggi serta kualitasproduk. Kebijakan ini akan bermakna manakala dikaitkan menggunakan upayapemenuhan layanan manajemen lembaga pendidikan yang bermutu, program pengajaranyang bermutu, fasilitas pendidikan yang bermutu, serta staf pendidikan yang bermutujuga. Terkait dengan konteks kekinian, pemanfaatan TIK dalam aplikasi kebijakanpenguatan tata kelola, akuntabilitas, serta gambaran publik forum pendidikan tinggi,implementasi sistem informasi pada pelayanan manajemen pendidikan tinggi sudah tentumampu dikatakan sangat tepat. Efektivitas implementasi TIK dalam pengelolaan perguruan tinggi perlu mendapatperhatian yang lebih mengingat kiprahnya yang relatif sentral dalam proses pengambilankeputusan manajerial ataupun keputusan-keputusan lainnya. buat menaikkan efektivitasimplementasi ini, yang kentara akan berpengaruh pada efektivitas pencapaianpenyelenggaraan pendidikan yang dilaksanakan forum, maka faktor-faktor yangberpengaruh pada efektivitas implementasi TIK pada pengelolaan kelembagaan,khususnya pada hal administrasi akademik perlu diteliti lebih lanjut. Ini ditujukan supayaproses manajemen akademik di perguruan tinggi sebagai lebih efektif serta efisien sebagaiakibatnya bisa menunjang pencapaian kinerja tinggi asal forum
Empirical Support for a Dual Process Model of the P-Factor: Interaction Effects Between Preschool Executive Control and Preschool Negative Emotionality on General Psychopathology
Authors: Phillips Eric , Brock Rebecca L , James Tiffany , Nelson Jennifer M , Espy Kimberly Andrews , Nelson Timothy
Published: July 2022

Recent work indicates that a general factor, often referred to as the p-factor, underlies nearly all forms of psychopathology. Although the criterion validity and utility of this general factor has been well supported, questions remain about the substantive meaning of the p-factor. The purpose of the present longitudinal study was to empirically test the hypothesis that the p-factor reflects dysregulation arising from a combination of high dispositional negative emotionality and low executive control. The current study examined preschool executive control, measured using a battery of nine developmentally appropriate executive control tasks, as a moderator of the association between preschool negative emotionality and both concurrent and subsequent levels of general psychopathology in preschool and elementary school using a community sample (N= 497). Latent moderated structural equation models demonstrated that preschool executive control significantly moderated the associations between preschool negative emotionality and general psychopathology both in preschool and approximately five years later in elementary school. These results suggest that the general factor of psychopathology may reflect dysregulation arising from a tendency to experience high negative affect, without sufficient executive control to effectively down-regulate that affect. This work has important implications for identifying transdiagnostic targets for prevention and intervention efforts, as well as furthering understanding of the substantive meaning and construct validity of the general factor of psychopathology.
In the eye of the beholder: Social traits predict motor simulation during social gaze
Authors: Prinsen Jellina , Alaerts Kaat
Published: July 2022

Previous research has robustly demonstrated that mutual eye contact between actor and observer promotes the simulation of perceived actions into the observer’s own motor system, which in turn facilitates successful social perception and communication. The socially relevant connotation embedded in eye contact may however be different for individuals with differing social traits. Here, we examined how normal (i.e. non-clinical) variability in self-reported social responsiveness/autistic traits, social anxiety and interpersonal relationship style (secure, avoidant or anxious attachment) influences neural motor simulation during action observation in different gaze conditions. To do so, we analyzed an existing dataset involving 124 adult participants (age range: 18-35 years) who underwent transcranial magnetic stimulation (TMS) while observing an actor performing simple hand actions and simultaneously engaging in mutual eye contact or gazing away from the observer. Motor evoked potential (MEP) amplitudes were adopted as an index of motor resonance. Regression-based analyses highlighted the role of social responsiveness and secure attachment in shaping motor resonance, indicating that socially responsive motor resonance during dyadic gaze (i.e., MEPdirect > MEPaverted) was only observed in participants displaying high levels of these traits. Furthermore, a clustering analysis identified three distinct subgroups of participants with unique social trait profiles, showing a clear differentiation in motor resonant patterns upon different gaze cues that is in accordance with a recent neurobiological framework of attachment. Together, results demonstrate that motor resonance within a given social interaction may serve as a sensitive tracker of socio-interactive engagement, which allows to capture subclinical inter-individual variation in relevant social traits.