bluuebunny/crossref_metadata_2025 huggingface dataset:
Kocher-Langenbeck Approach in Prone Position
Authors: Shafiei Seyyed Hossein , Siavashi Babak , Mahdavi Farhad , Heshmati Mohammad , Sadeghi Mohammad Reza , Golbakhsh Mohammad Reza
Published: June 2020

Background: The posterior approach for acetabular fractures is the Kocher-Langenbeck (K-L) approach which is performed in lateral and prone positions. Lateral position is a familiar position for most orthopedic surgeons. Prone position yields multiple advantages compared to lateral position.
Methods: Between years 2016 and 2019, 18 patients with selected acetabular fractures in which the best decision was surgical fixation using K-L approach were studied. The surgical procedure was done using K-L approach with the patient in prone position and we used Matta scoring system to evaluate post-operative reduction quality.
Results: According to the Matta system, the anatomic reduction was observed in 13 patients (86.6%). Imperfect reduction was observed in 2 patients (13.3%), no patient had poor reduction. Avascular necrosis (AVN) of the femoral head was seen in one patient (6.6%) and no infectio and heterotopic ossification (HO) were noted.
Conclusions: The advantage of this approach in prone position is believed to be better exposure and greater access to the quadrilateral plate (QLP) and anterior column indirectly. One of the most important advantages is that in prone position, handling the reduction devices to indirectly reduce anterior column or QLP is much easier
Knowledge, attitudes, and practices surrounding COVID-19 among Sudan citizens during the pandemic: an online cross-sectional study
Authors: Altayb Mousa Khawla Nasr Aldeen , Saad Malaz Malik Yousif , Tayseer Bashir Abdelghafor Mohammed
Published: June 2020

Background: A number of protective and cautionary protocols have been adopted to control the rapid spread of COVID-19 in Sudan. People’s commitment to these protocols is affected by their knowledge, attitudes, and practices (KAP).
Objective: To measure the Sudanese population’s KAP in relation to COVID-19 during the pandemic.
Method: A web sample was enrolled with success via the authors’ relations with citizens and standard media in Khartoum, Sudan. A self-administered online KAP questionnaire was completed by the respondents.
Results: Among the study sample (n=2336),66.4% between 18 and 29 years old, 60.7% were ladies, 75.9% had a high school education, and 76.1% were Khartoum citizens.  The general correct rate of the knowledge questionnaire was 84.7%. The majority of the participants (94.8%) were ready to commit to the decision of staying at home. A large proportion of the participants (92%) frequently washed their hands or using antiseptic.
Conclusion: Health teaching programs geared to enhancing COVID-19 knowledge are useful for Sudan citizens fostering positive attitudes and disseminating knowledge relating to helpful practices. Due to the limited sample representativeness, we must be cautious when generalizing these findings.
Keywords: Knowledge, Attitude, Practice, COVID-19, Sudan.
Bactrim 'Roche' en el tratamiento de la cistitis
Authors: González Arizabaleta Danilo
Published: June 2020

Fueron tratadas 20 pacientes pertenecientes al sexo femenino con Cistitis comprobada por medios clínicos, paraclínicos y bajo visión directa por medio de la endoscopia urológica.Se utilizó un nuevo producto compuesto por la asociación de 80 mg. de Trimetoprim y 400 mg. de Sulfametoxazol (BACTRIM 'Roche'), suministrado por vía oral y en las dossi de dos tabletas tres veces al día por una semana. Los resultados fueron satisfactorios en el 95% de los casos, considerándose a las pacientes curadas al fin del tratamiento.Las pacientes fueron seleccionadas descartándose cualquier origen obstructivo.
Embarazo ectópico avanzado
Authors: Zabaleta Lombana Alberto
Published: June 2020

Hemos recopilado entre,1958 y 1974, trece casos de embarazo ectópico avanzado, atendidos en la Clínica Universitaria Maternidad Rafael Calvo de Cartagena.
Tratamiento de la Tricomoniasis. Evaluación comparativa entre Tinidazol y Metronidazol
Authors: Velasco Chiriboga Alvaro , Márquez Mariño Gustavo
Published: June 2020

Se hace un ensayo clínico comparativo del tratamiento para tricomoniasis con tinidazol y metronldazol, empleando los esquemas terapéuticos recomendados para cada una de estas sustancias. Se trataron 25 casos con tinidazol y 20 con metronidazol. Se obtuvo un 96% de curaciones con tinidazol y un 66.6% de curaciones en las pacientes tratadas con metronidazol. Al repetir el tratamiento los porcentajes se elevaron al 100% y 72.2%, respectivamente. Mientras que en el grupo del tinidazol la colaboración fue completa, en el de Imetranidazol se apreciaron rechazos y deserciones, razón por la cual se propone a tinidazol como la droga a emplear en campañas de erradicación. Ambas drogas resultaron inocuas a las dosis utilizadas.
El sufrimiento fetal agudo y los medicamentos útero-inhibidores
Authors: Karchmer K. Samuel , Shor Pinsker Velyl , Guevara Rubio Guillermo
Published: June 2020

El análisis de las metas de la obstetricia actual revela como uno de sus mayores logros en los últimos treinta años, la disminución impresionante de la mortalidad materna; sin embargo, la mortalidad perinatal ha permanecido sensiblemente estática en una cifra elevada si se le compara con otros grupos de edades, e inclusive hasta con épocas avanzadas de la vida.
Aborto séptico en el ICSS.
Authors: Velasco L. Germán
Published: June 2020

Un grupo de 29 pacientes de los servicios obstétricos del ICSS con abortos sépticos complicados, todos provocados, se manejan de acuerdo a criterios definidos. Diez casos con patología anexial, doce de peritonitis y siete septicemias cuya permanencia promedio fue de 13, 20 y 36 respectivamente, con un total de 575 días cuyo costo se estima en dos millones  de pesos. Sóol hubo una defunción. Se sugieren modificaciones a la clasificación del I.M.I. Se recomienda la intervención quirúrgica del foco séptico primario, recalcando la utilidad de la colpotomía; cada paciente requirió dos cirugías. Se verifica la bondad de la penicilina y se insiste en la combinación de antibióticos que se rotan cada 4 a 5 días, si es necesario. Las maniobras abortivas haitualmente practicadas por auxiliares de enfermería y comadronas, en casa de las pacientes, con un costo muy bajo utilizando sonda, a veces con alambre, dieron cuatro perforaciones uterinas y dos de sigmoide; el motivo conciente fue el económico, la soltería, la planificación familiar y el temor a perder el empleo. Se encontraron abortos clandestinos, temor a perder el empleo y salarios por debajo del mínimo legal.
Carcinoma de la vulva. - Análisis de 17 casos.
Authors: Jubiz H. Alfonso
Published: June 2020

Los tumores malignos de la vulva no se ven favorecidos paar su estudio porque su baja frecuencia le ha restado importancia en relación a los otros tumores del aparato genital femenino. Se acepta que el 3.4% de todos los canceres del aparato genital femenino corresponden a la vulva y es el tercero de los de la pelvis femenina.
Gemelos unidos simétricos (Siameses)
Authors: Pérez Agudelo Ernesto
Published: June 2020

Se reporta un caso de Gemelos Unidos Simétricos tipo Thoracopagus nacidos por parto vaginal. El diagnóstico se hizo al obstruirse el parto en el segundo período. El Monstruo Doble nació muerto y pesó 3.300 grs. es de sexo femenino. Nacieron en el I.M.I. de Bogotá productos de una madre de 17 años cuyo embarazo no fue controlado.Se hace un comentario acerca de la frecuencia, clasificación, embriogénesis, etiología, diagnóstico y tratamiento.
Efecto de la Desamino-Oxitocina Bucal sobre la contractilidad Uterina durante la Inducción del Parto
Authors: Rodríguez Aristarco , De Villamizar Mery , Cobo Edgard
Published: June 2020

Se estudian los efectos sobre el útero humano de la oxitócina sintética (DAO); la actividad uterina se mide por registros de presión íntra-amniótica. El estudio comprende 24 embarazadas normales a término con trabajo espontáneo como grupo de control, y 22 en quienes la inducción electiva tiene causas médicas, como grupo de control. Tabletas con 50 unidades de la droga aplicaron cada hora, en el surco gíngivo-labial.Se verificó aumento significativo de la actividad uterina después de la tercera tableta y el aumento se debe principalmente a la mayor intensidad de la contracción.La duración del primer período del parto fue más corta en el grupo experimental. No hubo diferencias en los recién nacidos de uno u otro grupo. Sin embargo, aconsejamos precaución en el manejo de la (DAO).
Tumores de Ovario gigantes asociados con embarazo
Authors: Hernández Romero Marco A. , Arzura Estrada Leonardo
Published: June 2020

Se hace la revisión de 3 casos interesantes de tumores ováricos asociados con embarazo, estudiados y tratados en el Instituto Materno Infantil de Bogotá. Dos de ellos fueron descubiertos durante el embarazo; uno con gestación a termino y el otro a las 14 semanas. El tercer caso se descubrió a los 20 días de puerperio. Fueron descritos como tecoma, quiste folicular y quiste del cuerpo lúteo respectivamente; todos gigantes, siendo los primeros que se diagnostican en el Instituto asociados a embarazo.Se indica además el tratamiento quirúrgico que se practicó en cada caso. Todos los controles posteriores fueron satisfactorios.
Remoción de cavidad abdominal de un dispositivo intrauterino por culdoscopia
Authors: Acosta Bendek Eduardo
Published: June 2020

Una de las complicaciones más serias de los dispositivos intrauterinos es la perforación uterina, la cual se inicia desde el momento de su inserción.
Papel de arginina-vasopresina (A.D.H.) en la regulación de la motilidad uterina durante la menstruación
Authors: Cobo Edgard , Cifuentes Rodrigo , De Villamizar Mery
Published: June 2020

En 27 mujeres normales, solicitaron la inserción de un dispositivo intrauterino anticonceptivo (DIU) a la Consulta Externa del HUV, se obtuvo aceptación voluntaria para estudiar las actividades uterina y antidiurética e inducir una diuresis acuosa durante la menstruación y en las 2 a 3 horas previas a la inserción del DIU. La diuresis acuosa, abtenida adm nistrando sobrecargas de agua por vía oral e intravenosa (20 ml/Kg. de peso corporal), produjo una inhibición simultánea de la alta contractilidad del útero menstrual y de la actividad antidiuréca. Este efecto se comunica por primera vez a la literatura médica.Estos resultados, así como los de otros estudios preliminares que discutimos en éste artículo, refuerzan claramente la hipótesis que plantea la participación de la vasopresina u hormona antid urética (ADH), en la regulación de la elevada contractilidad uterina característica de la menstruación.
Sección de Información
Authors: De Obstetricia y Ginecología Federación Colombiana
Published: June 2020

Simposio Internacional sobre ecología fetalCongreso internacional de Obstetricia y Ginecología Psiosomaticas en Roma.Programa Científico preliminarAactividades científicas del instituto Dexeus - Departamento de Obstetricia y Ginecología.
“The Wayfarer” (“The Pedlar”) by Hieronymus Bosch as an Archetypal Image of an ‘Other-Stranger’
Authors: Kisiel Przemysław
Published: June 2020

One of the most important contemporary experiences of European societies is undoubtedly the migration crisis. The resulting social fears of ‘strangers,’ which have been activated, show how important the archetypical ‘other-stranger’ pattern still is, and that it can be treated as an example of an ‘anthropological constant.’ The aim of the article is to try to look at the painting “The Wayfarer” by Hieronymus Bosch as an illustration of the archetypical ‘other-stranger’ pattern. It seems that such a reading of this work, rich in symbolic content, on the one hand perfectly justifies the thesis of the archetypical sources of contemporary attitudes towards ‘strangers’ and, on the other hand, allows one to better understand and explain the current reactions and behaviors of Europeans. This becomes particularly evident when juxtaposing the image of Hieronymus Bosch with the contemporary media images of migrants.
Separujące i ochronne funkcje izolacji. Narzędzia oswajania inności na przykładzie działalności artystyczno-edukacyjnej Teatru 21
Authors: Kalinowska Katarzyna , Rożdżyńska Kaja
Published: June 2020

Celem artykułu jest refleksja nad kierunkami pracy nad oswajaniem inności w działalności artystów i pedagogów teatru z kręgu Teatru 21. Przedstawiamy model integracji inności przez sztukę teatralną, który ma za zadanie zniesienie barier włączania i zerwanie społecznych „izolacji” oddziela­jących osoby z niepełnosprawnością od społeczeństwa. Jednocześnie ów model przewiduje nałożenie nowych form ochronnych, których główną funkcją jest asekuracja uczestników interakcji polegającej na kontakcie z Innym. W artykule omawiamy metody i narzędzia wykorzystywane w pracy edukacyjnej Teatru 21 oraz zastanawiamy się nad efektami ich zastosowania w procesach zmiany postaw wobec niepełnosprawności. Podstawą empiryczną artykułu są wnioski z badań przeprowadzonych podczas ewaluacji projektu O!Swój Teatru 21 w latach 2017–2018. Działalność artystyczna i edukacyjna Teatru 21, tworzonego w większości przez aktorów z zespołem Downa, koncentruje się na wspomaganiu proce­sów integracji społeczno-kulturowej osób z niepełnosprawnościami. Omawiany model oswajania inno­ści wypracowany przez środowisko Teatru ma jednak mocno uniwersalny rys i w naszej ocenie może zostać zaadaptowany do pracy z różnymi wymiarami inności.
Bilateral Carotid Body Paraganglioma
Authors: Warachit Wasita , Houngngam Natnicha , Snabboon Thiti
Published: June 2020

N/a.
Reply to a Comment about the Article Published in Acta Med Port 2020; Apr 27; doi:10.20344/amp.13928
Authors: Nogueira Paulo Jorge , De Araújo Nobre Miguel , Nicola Paulo Jorge , Furtado Cristina , Vaz Carneiro António
Published: June 2020

N/a.
Religiosity of pharmacy students of UIN Malang during COVID-19 pandemic
Authors: Syahrir Ach. , Rahem Abdul , Prayoga Adistiar
Published: June 2020

Coronavirus Disease (COVID-19) has become a global health problem since it was declared as a pandemic by the World Health Organization (WHO) as of March 11, 2020. Data from Johns Hopkins University (as of May 30, 2020) states that 5,930,096 cases confirmed in worldwide with a total fatality rate of 6 percent The prevention from COVID-19 transmission is to maintain the immunity. One way to maintain immunity is to maintain mental health by maintaining the religiosity factor. The development of technology and information causes information COVID-19 cases circulate quickly and massively. This condition can indirectly affect mental health and behavior change of affected entities. The student of the Faculty of Pharmacy, Maulana Malik Ibrahim State Islamic University (UIN Malang) is one of the affected entities of COVID-19. This study aims to determine the religiosity of the Faculty of Pharmacy students in facing COVID-19. The respondents of this study were 117 students of Pharmacy UIN Malang. The method used in this research is descriptive observational, with the aim to determine the religious practice or conditions of worship of students when facing an outbreak of COVID-19. The research instrument used in the form of a questionnaire related to the indicators and dimensions of the student religiosity that has been tested for validity and reliability.
Changing of cytokine status in acute period of tick-borne neuroinfections in children
Authors: Bedareva T. Yu. , Poponnikova T. V. , Galiyeva G. Yu. , Pinevich O. S. , Vakhrameyeva T. N.
Published: June 2020

Activity of cytokines of tick-borne infection of children was researched. Revealed low level of interferon-γ concentration testify about abnormality of cellular link immune protection and typical for focal forms of tick-borne encephalitis. Severe forms of disease run with background increase of interleukin-6 and interleukin10. Maximum increase of tumor necrosis factor-α was detected in cases of mixed-infections. Borreliosis infection flows with background domination of Th-2 over Th-1 type of immune response.
The use of psychodiagnostic methods in the process of psychocorrection cures of a patient with the disseminated sclerosis
Authors: Subbotin A. V. , Semyonov V. A. , Getmanenko I. M. , Korotkevitch N. A. , Arefiyeva Ye. G.
Published: June 2020

Psychodiagnostics has various evaluation methods of psychicprocesses, characteristics and mental conditions. It is important to define the actual emotional condition and learn whether a patient has the depressed disorder. This is especially important if to take into consideration the possibility of the psychoemotional disorders correction works. The aim of the given research is to select the methods to diagnose a man’s emotional sphere. The chief task of the research is to reveal the most efficient methods to define the changes in a patient’s condition after the psychocorrection work took place. As a result of the experiment we have found out that an anxiety, connected with the adaptation period to the diagnosis of disseminated sclerosis, can be easily cured. And this fact contributes to standardization of emotional estimation while perceiving a man his or her life. These results are confirmed by the hospital scale HADS that we have chosen to demonstrate the real indices changes. The present researches can be useful in a psychological assist at neurological department.
Morphologic functional characteristics in middle and elderly aged women with ischemic stroke
Authors: Kukhareva I. N. , Doronin B. M.
Published: June 2020

The morphologic functional characteristics in middle and elderly aged women with ischemic stroke were examined. It is shown that disease difficulty and disablement group definition may be explain by oestrogen deficit – one of risk factors.
Apoptosis cells and regulation factors in patients with multiple sclerosis
Authors: Vostryakova S. A. , Alifirova V. M. , Ivanova S. A.
Published: June 2020

Study process apoptosis cells in relaption and remittion in 91 patients with multiple sclerosis. Study apoptosis cells in patients with multiple sclerosis. Absolut apoptosis cells in remittion high.
Vital exhaustion and risk development of the stroke in general population men in 25–64 years old (epidemiological investigation of basis program WHO MONICA-psychosocial)
Authors: Gafarov V. V. , Gromova Ye. A. , Gafarova A. V. , Kabanov Yu. N. , Gagulin I. V.
Published: June 2020

Risk of the stroke in population men in 25–64 years old with vital exhaustion in the course of 14 years was examined. WHO-MONICA-psychosocial program are using. Workers and low education men has risk of the stroke more often. Risk of the stroke in the 25–64 years old men population associated with vital exhaustion.
Early and late results of surgical treatment of multifocal epilepsy
Authors: Kasumov V. R.
Published: June 2020

Studies of surgical outcomes in multifocal epilepsy patients showed them to depend on epileptic foci sites in two groups of the diseased according to J. Engel scale (1993): 92 early postoperative period patients (group 1), and 30 late one patients (group 2). Of 92 group 1 patients unilateral cortical epileptic foci were diagnosed in 62 (51.7%), bitemporal ones in 30 (20.0%) patients. Of 30 group 2 patients – unilateral cortical in 17 (42.5%), and bitemporal in 13 (32.5%) patients. In group 1 remission of the seizures and decrease of their frequency over 80.0% was achieved in 80.4% of the patients, in group 2 – decrease of seizure frequency over 50.0% in 67.7%, and recurrent seizures in 26.7% of the patients.
Cognitive disturbances at convalescents with the meningeal form tick-borne encephalitis and a mikst-infection
Authors: Nadezhdina M. V. , Fedchuk T. N. , Toporkova M. G. , Skulskaya N. I. , Mahnyova N. A.
Published: June 2020

The operative, long-term memory (Mendelevich V.D. technique, 1999) and attention (proof assay of Burdon) at 96 convalescents with the meningeal form tick-borne encephalitis (CTBE) and 23 – mikst-infection (CMI) three age groups in late regenerative (6–12 months) and remote (till 2 years) the periods is investigated operative. The greatest is taped message comprehension quality indicators of a long-term memory and parameters of proof assay of Burdon. In the remote period сognitive disturbances were taped at all convalescents, prevailed at CMI and in III age group. Obtained data can form a basis for an expert estimation of state of health CTBE and CMI and prove medicamental correction at a stage of a dispensary observation.
Diagnostics and treatment of traumatic brain injury in children
Authors: Kolmakov D. V.
Published: June 2020

In this work, we have analyzed 2 774 case records of children after traumatic brain injury for the period of 2003 to 2007 (based on materials of the Tomsk Municipal Children’s Hospital No. 4). The age structure and causes of a traumatic brain injury have been analyzed. Most often complaints of children coming to the hospital are revealed, as well as typical changes in the cerebral hemodynamics (from the data of по данным rheoencephalography) and some parameters characterizing the neurological status of patients immediately after the injury and six months later. Based on the analysis of case records and health status questionnaires of children having traumatic brain injury up to six months later, it is shown that parents of patients in some cases do not adhere doctor’s recommendations after leaving the hospital. The therapy of traumatic brain injury in children requires successive treatment in hospital and at home and development of simple and acceptable rehabilitation schemes for children.
Vegetative dysregulation in a groups with tumor of a brain and chronicle vessel encephalopathy patients
Authors: Tatarenko S. A. , Bein B. N.
Published: June 2020

The sympathetic skin response and the spectral analysis of the heart rate variability at 25 patients with a tumor of a brain, at 39 patients with chronicle vessel encephalopathy, and also at 30 healthy examinees with the help of a computer complex "VNS-spectrum" are investigated. Quantitative shifts and the sign differences significative of change of descending influences of the suprosegmental vegetative centers, with imbalance sympathetic both parasympathetic nervous systems and humoral the channel of the regulation, distinct from norms, and also patients differing between groups a tumoral and vascular pathology are established. Changes of separate parameters are supplemented with distinctions within the group correlation mutual relation between parameters of the spectral analysis variability an heart rhythm.
Epidemiology of patients with adenomas of pituitary in industrial city
Authors: Shakhvorost N. P. , Zhestikova M. G. , Meechkayeva V. I. , Dantsiger D. G. , Aikeena T. P. , Bryzgalina S. M.
Published: June 2020

Adenomas of pituitary (AP) make up about 10% of all intracranial tumours, which are met in practice of an endocrinologist or neurologist. As a rule AP are sporadically, however one must not consider them as an isolated disease. 52–62% of patients with hyperprolactinemia have AP. According to the data of. Federal Several of state statistics of the Russian Federation (2006) the amount of sick people with hyperprolactinemia among adult population can very from 214 thousand to 2 million people. About 80% make up young women at the age of 24–40 years old. 25% AP do not show superfluous hormonal secretion, they are clinically hormonally inactive, that embarrasses early diagnosis. In Novokuznetsk more than 50% of volumetrically brain formations make up AP. For last 10 years primary diseases AP has increased in 1.6 times. In Novokuznetsk there are factors increasing risk of forming of different neuroendocrinal diseases, high quantities of individual and population risks of oncologist pathology, deterioration of reproductive health, high levels of invalidism of population at able-towork age because of environment pollution and harmful work conditions. The examinations of expansion of AP disease at citizens of town Novokuznetsk show the necessity of introduction of register of dispensary for this category of sick people.
Signs of brain organic lesion in patients examined in the acute period of ixodic tick-borne borreliosis
Authors: Zheleznova I. O. , Balashov P. P. , Lepyokhin A. V.
Published: June 2020

Signs of organic lesion of brain have been studied in 85 patients in the acute period of tick-borne borreliosis. The analysis of results of clinical and clinical-psychopathological studies has revealed signs of brain organic lesion (BOL) in 100% cases. In the studied group, the moderate degree of BOL signs is most often (54%), mild cases are somewhat rarer (41%), and the pronounced degree is confidently rarer (5%). The degree of manifestation of signs of brain organic lesion depends on the age and the somatic-neurological burdened background of patients and influences the course of the acute and remote periods of ixodic tick-borne borreliosis.
Indices of neurodynamics of stress-reactivity in adolescent people with different types of coronary behavior
Authors: Kuvshinov D. Yu. , Tarasenko N. P.
Published: June 2020

The coronary behavior of type A is one of the risk factors for development of cardiovascular diseases, but its peculiarities in adolescent people is poorly studied. It is shown that representatives of type A have the higher level of stress-reactivity, higher excitability, lability of nervous processes, addiction to abstract thinking, that is, behavior of type A is characterized by particular psychophysiological reactivity. In people of coronary type A, the external behavioral strategy is likely connected with activation of psychic processes to the higher extent. In people of type B, stresses probably do not play a destructive role, but are a kind of stimulus improving neurodynamic indices.
Population appraisal of health and quality of medical aid as indexes of conducted modernization in public health service
Authors: Khlynin M. S.
Published: June 2020

Is determined that the population’s attitude to accessibility, quality of charge-free and paid medical services is depended on a financial status, state of health, availability of diseases and age. The paid medical service development will reduce the use of medical aid according to the compulsory medical insurance program that will allow to spend more resources on less wealthy groups of people. The expediency of health indexes monitoring, competitive relations development, motivation in public health service is proved to be necessary.
Main directions of prophylaxis of untimely mortality from cardiovascular diseases
Authors: Adamyan A. T. , Kladov S. Yu.
Published: June 2020

The mortality of Tomsk people aged from 15 to 74 from diseases of the blood circulation system have been studied for 1990—2001 and main risk factors have been determined. For the 12-year period, the mortality increased in all the main classes of causes of death. The analysis of differences in male and female mortality from individual causes of death shows that cardiovascular diseases and violent death in the active working age are major contributors to mortality differentiation depending on sex. Four risk factors can be separated: high arterial tension, high cholesterol level, smoking, and excessive alcohol consumption. They determine 87.5% in total mortality and 58.5% in the years of life with disability. Prophylaxis of mortality from circulatory diseases should be aimed, first of all, at these groups of factors.
Experience of participation of a private medical enterprise in the pilot project «Modernization of Health Service in Tomsk Region»
Authors: Zaviyalova G. N.
Published: June 2020

The activity of the medical enterprise Medsanchast' No. 3 within the pilot project «Modernization of Health Service in the Tomsk Region» in the form of integration in the obligatory medical insurance (OMI) system has been analyzed. Medsanchast' No. 3 has achieved significant progress in the work on the increase of its fraction if the OMI system. However, in the process of implementation of the pilot project, a critical financial situation took place due to age characteristics of new contingent and, as a consequence, payment for acute hospital aid. To solve this problem, it is necessary to revise the charge for urgent hospitalization and the order of population assignment to medical-prophylactic enterprises, thus creating equal conditions for private clinics, and to tighten control over cases of urgent hospitalization.
Characterization of migration flows in the Tomsk Region and their role in formation of the demographic situation
Authors: Kladov S. Yu. , Konobeyevskaya I. N. , Karpov R. S.
Published: June 2020

Starting from 1992, the demographic situation in the Tomsk Region is characterized by a decrease of the population. It is mostly affected by the natural migration of population. The tendency of increase (decrease) in the birth rate is mostly determined by the past period. Thus, from 2000, the stable growth of the birth rate is observed in the Tomsk Region mostly due to the high birth rate in the early 1980s. On the average, the influence of the past period becomes visible in birth-rate indices 23–25 years later.
The earlier vascular and tissues reactions of free axial flap after its replantation and under the eplirs influence
Authors: Malinovskaya I. S. , Sinichev D. N. , Semichev Ye. V. , Baranova Ye. N. , Baitinger V. F. , Logvinov S. V.
Published: June 2020

Reaction of the skin vessels and tissues after microsurgical replantation of the free axial groin flap (FAGF) under the influence of eplir was investigated. Studying of skins vascular bed on microanatomical preparations was spent by means of a technique of an intravascular injection of Gerots mass and histological preparations. After transplantation FAGF signs of developments of stagnation, augmentation of numerical density of vessels are observed; restoration of vascular communications begins about 14 days. After application of various forms of eplir germination of vessels in surrounding tissues is observed with 7 days, morphological changes of a vascular bed are less expressed. Application of various forms of an extract a silt sulphidic muds essentially improves processes of adaptation and integration of free axial flaps.
The role of family anamnesis investigation in antiphospholipid syndrome
Authors: Chapayeva N. N. , Trifonova M. A.
Published: June 2020

The investigation of 82 families of patients with antiphospholipid syndrome (APS) was performed. APS was diagnosed in 1st-degree relatives and woman more frequently. Minor features of APS were revealed in half of relatives, lupus anticoagulant (LA) — in a third of them. If person has APS in family anamnesis, minor features of APS or (and) LA, pre-APS can be diagnosed and primary prevention of thrombosis can be conducted.
The role of lysosomal cysteine proteases in tumor progression
Authors: Korovin M. S. , Novitsky V. V. , Vasiliyeva O. S.
Published: June 2020

Cysteine cathepsins have been known for a long time to play an important role in cancer progression. Here we summarize their impact to the hallmark processes of malignant growth such as cell proliferation, apoptosis, angiogenesis, invasion and metastasis. We discuss the molecular mechanisms where cysteine cathepsins are participating through the degradation of the extracellular matrix, initiation of the proteolytic cascade by activating serine proteases and urokinase plasminogen precursors. Moreover, in addition to the tumorigenic and pro-metastatic functions of lysosomal cysteine proteases in the cancer cells, cathepsins originating from cells of the tumour microenvironment has been shown to participate in the processes leading to the tumor progression and metastasis. Taken together, that data support the concept of cysteine cathepsins as promising molecular targets for cancer therapy.
Interaction between dislipidaemia, atherosclerosis of carotid artery and cognitive impairment in discirculatory encephalopathy
Authors: Vasilenko A. F. , Artyomova N. S. , Shamurov Yu. S.
Published: June 2020

107 patients with discirculatory encephalopathy were examined. The main syndromes of the disease were a mild cognitive impairment, vascular parkinsonism, pseudobulbar, ataxia. Сorrelations between level cholesterol, lipoproteids low density in the blood with extent of atherosclerosis in the carotid artery and cognitive functions were analysed. The presence of atherosclerotic plaques, not thicking of intima-media complex, correlates with changes of memory and attention.
Clinical-constitutional features in patients with vegetative dysfunction and emotional disturbance
Authors: Voropai N. G. , Doronina O. B.
Published: June 2020

Аutonomic dysfunction and psychic tension have both and several properties. Anthropometric measurements, research of vegetative tone and vegetative reactivity, research of neurological status were conducted.
The research of genes series polymorphisms of brain neurotransmitter system and of the opioid reception at narcotized persons
Authors: Сherepkova Ye. V. , Gribacheva I. A.
Published: June 2020

Alleles frequencies and polymorphisms genotypes frequencies of gene DRD4 (VNTR), gene DAT (VNTR), gene 5-HTT (VNTR and ID) and gene OPRM1 (SNP) were investigated at Russian males taking narcotic substances. It was determined that genotype 4/3 occurs only at persons taking narcotic substances, the most often occurring polymorphism of gene DRD4 is genotype 4/4 in all groups. It was detected that the polymorphism of gene DAT at narcotized persons is presented by the high enough part of genotypes 9/10 and 10/10, but in the rest of groups the distribution is the same. At narcotized persons and in the control group, the carriers’ part of genotype I/D of gene 5НТ2А is high. The genotype D/D occurs only at persons taking narcotic substances. The genotype10/10 of gene 5НТ2А occurs more often than in population group, which conforms to the literature data.
The aqueous interchange's condition in case of cerebrovascular pathology
Authors: Borodin Yu. I. , Pesin Ya. M. , Doronin B. M. , Omorov N. K.
Published: June 2020

When the cerebrovascular patology exists, the interstitial fluid decreases. Because of that the area of the brain decreases and the area of the ventricles increases.
Pituitary adenomas and their structure in a large industrial center (Novokuznetsk)
Authors: Shakhvorost N. P. , Zhestikova M. G. , Michkaeva V. I. , Dantsiger D. G. , Aikina T. P. , Bryzgalina S. M. , Minenkov V. A.
Published: June 2020

In 1992 Kemerovo region in the Russian Federation was first admitted as the area with an extraordinary ecological situation. Living in Kuzbass is factor of risk of forming of different endocrine diseases, deterioration of reproductive health, high quantities of individual and population risks of oncologist pathology, high levels of invalidism of population at able-to-work age because of environment pollution and harmful work conditions. The present study includes 299 sick people with confirmed diagnosis of adenomas of pituitary in the endocrine department of the town hospital № 1 for the period from 1995 to 2007 that is complete selection. Adenomas of pituitary are more often detected at people at active able- to-work age. Adenomas of pituitary are more often diagnosed at women 87,0%. The overwhelming majority of adenomas of pituitary (74,0%) is detected at the age of 20—50. Because of this disease 99 people (33,1%) have different degree of loss of their working ability. In the structure of adenomas prolactinomas dominate (53,5%), on the frequency of meeting hormonally inactive adenomas are on the second place (32,1%), somatotrophinomas are rarely met (in 11,7%) and the rarest ones at the population on Novokuznetsk are corticotrophinomas (in 2,7%). On dimensions of adenomas of pituitary microadenomas predominate — at 68,0% sick people. The relation microadenomas to macroadenomas is 17 : 22 at men and 187 : 73 at women.
Clinical features of supranuclear palsy
Authors: Valikova T. A. , Alifirova V. M. , Pugachenko N. V. , Tsyrenzhapova R. B. , Bichik A. B.
Published: June 2020

Progressive supranuclear palsy related to neurodegenerative diseases of the brain. In the pathological process involved, and stem structure. The disease manifests a combination of progressive akinetic-rigid syndrome and early development of postural instability leading to frequent falling. Observed supranuclear ophthalmoplegia, pseudobulbar syndrome and dementia of frontal. Arises at the age of 50—60, rapidly progressive, and untreatable protivoparkinsonicheskimi drugs. An clinical case of a patient 59 years old, with these magnetic resonance imaging of the brain.
Some aspects of the clinical picture and dynamics of the postwithdrawal period in opium addiction patients
Authors: Abetova A. A. , Meldekhanova M. T.
Published: June 2020

The psychopathological pattern of the postwithdrawal state in opium addiction patients is discussed. The pathological addiction to the drug in dependence of premorbid personality characteristics and the inverse dynamics are analyzed.
Application of ozone and plasmapheresis in complex treatment of uveitis
Authors: Chernyshyova A. D.
Published: June 2020

A new method of treatment of endogenous uveitis have been developed. The method is based on the application of metabolic plasmapheresis with ozonization of cellular weight. Comparative analysis of the treatment results of three groups of 179 patients (209 eyes) has revealed significant superiority of original modification of plasmapheresis. The effect of the presented method of treatment, in authors’ opinion, is caused by immunomodulating effect of plasmapheresis and ozonotherapy, bactericidal and antiviral effects of ozonotherapy. The paper also presents some sanogenetic mechanisms of a new method of treatment – a liquidation of T-cellular immunodeficiency, a decrease of level of circulating immune complexes and some others.
Scin cancer incidence rates in Krasnoyarsk Region
Authors: Pobilat A. Ye. , Arutyunyan G. A.
Published: June 2020

Scin neoplasms are among the most common oncological diseases with the prevalence of basalioma. The paper рresents statistical analysis of the data of skin cancer morbidity and mortality rates in Krasnoyarsk Region summarized for the period since 1999 until 2007. In structure of the skin cancer morbidity defines a share basalioma and squamous cell carcinoma.
Correlative intercoupling of histomorphometrical values of different heart parts in norm and with chronic heart failure
Authors: Kazakov V. A. , Gutor S. S. , Sukhodolo I. V. , Shipulin V. M. , Krivoschyokov Ye. V.
Published: June 2020

The objective of the given study was to assess statistic dependence of histomorphometrical values of left ventricle (LV) and right atrium (RA) auricle myocardial condition in normal hearts (17 cases) and in hearts with chronic heart failure (CHF) (21 cases). Statistic dependence between morphometrical parameters in LV, RA auricle as well as between these heart parts in both patients without cardiovascular pathology and in patients with CHF was found. In the latter group the amount of correlations decreases in left ventricle and increases between the parts (LV and RA) in comparison with the norm.
The study of structural mechanical properties of «Kartalin» ointment
Authors: Kartalov M. G. , Dmitruk S. Ye. , Dmitruk V. S. , Romanenko T. V.
Published: June 2020

In this article the structure-mechanical properties research results of «Kartalin» ointment are being cited. This ointment shows the evident treatment-preventive activity with occupational and combinational dermatosis. It has been ascertained that the «Kartalin» ointment, being under consideration, appears to be structural liquid with expressive non-Newtonian flow character that is having high viscosity (100—200 Pa/s) and high yield point (20—40 Pa) with the temperature of usage 30—40 °C, which provides long skin protection. The flow properties of the composition are sufficiently time stable, which enables good preparation quality maintenance during long-term storing.
Mechanisms for formation of postoperative adaptation in complex treatment of thyropathy
Authors: Galyan A. N. , Popov O. S. , Udut V. V.
Published: June 2020

Surgical thyropathy correction is inevitably accompanied by specific change s in hormonal status. We have analyzed the ada ptation mechan - isms and compensat ory and adaptive reactions responsible for the whole life-support system of organism. On the basis of a number of organism homeostats nonspecific mechanism s of resistant and tolerant realisation strategies of long-term adaptation were studied, suppositions were made on possible effective course of adaptation reactions in the conditions of healthy thyroidal issue transplantation and cellular therapy use.
Design of electronic documents management system for Center of Postgraduate Education. Stage I: describe of workflow
Authors: Kaverina I. S. , Brazovskaya N. G.
Published: June 2020

Preparatory works on Design of electronic documents management system for SSMU Center of Postgraduate Education (CPE) were conducted. Workflow which accompany educational process of CPE students using tabular and graphic methods of information representation were described.
Regenerative treatment of a chronic prostatitis at participants of confrontations
Authors: Zaitsev A. A. , Barabash L. V. , Levitsky E. F. , Kolmatsui I. A.
Published: June 2020

The purpose of research was development of methods complex consecutive physiobalneotherapy a chronic prostatitis at participants of local conflicts. 83 participants of confrontations in the age of 23—37, with the verified diagnosis of a chronic abacterial prostatitis with an accompanying syndrome of vegetative dysfunction of a various orientation and a degree of expressiveness are surveyed and treated. Schemes of stage-by-stage rehabilitation have been developed for correction of poststressful infringements with purpose of base complexes at the first stage of regenerative treatment with addition at the second stage (with 7—10 days of treatment) local procedures. The lead comparative analysis of efficiency of medical actions specifies expediency of application consecutive rate of medical rehabilitation of participants of confrontations with the diagnosis of a chronic prostatitis.
West syndrome: ethiology, management, long-term outcomes
Authors: Krayeva L. S. , Alifirova V. M. , Grebenyuk O. V.
Published: June 2020

The article is based on long-term observation of 27 patients with West syndrome, age of onset, etiology of symptomatic forms, neurological status, efficiency of hormone therapy and antiepileptic drugs.
Reality and perspective of instrumental diagnostics hemostasis system functional state in critical medicine
Authors: Shpisman M. N. , Tyutrin I. I. , Udut V. V. , Ripp Ye. G. , Sorokozsherdiyev V. O.
Published: June 2020

In article to discuss diagnostic value of blood aggregate regulation system (BARS) and complexity of diagnostics, particularly, in critical state.Advantages and disadvantages of instrumental diagnostics technique were analyzed: thromboelastographia and lowfrequency piezoelectric hemocoagulographia of whole blood. Estimates new next-generation instrumental method of research - lowfrequency contact conductometry. This method permits to evaluate role blood plasma, cells hemostasis factors and wall of vessels in critical state BARS dysfunction.
Faculty Training and Professional Retraining of Specialists of the Siberian State Medical University — 30 years
Authors: Ogorodova L. M. , Alifirova V. M. , Timoshina Ye. L.
Published: June 2020

The main stages of the development of the Postgraduate Formation in Siberian State Medical University are presented. In 2009 was performed 30 years since day of the opening of the Faculty of the Improvement Specialists. Were analysed main totals to activity of the faculty, its formation and development, perspective directions in training high-quality personnel for practical public health.
Calcium consumption by nursing mothers and children from risk groups on decreased mineral bone density in different age periods under conditions of the city of Tomsk
Authors: Kondratiyeva Ye. I. , Gaprindashvili Ye. G. , Barabash N. A. , Stankevich S. S. , Ryzhakova N. A. , Yankina G. N. , Shemyakina T. A.
Published: June 2020

We have studied the calcium consumption by nursing mothers and children from risk groups on decreased mineral bone density in different age periods under conditions of Tomsk. The calcium content in breast milk in the first six month of lactation was determined by the method of instrumental neutron-activation analysis. It has been found that the calcium consumption by the most nursing mothers corresponded to physiological norms. In the lactation dynamics, the calcium content in the breast milk decreased at the third month and increased at the sixth month of lactation. The average calcium consumption was (834,3 ± 132,3) mg in children aged of 1—3 and (959,0 ± 99,5) mg/day in children of 4—6 years old. Among schoolchildren, the average calcium consumption was (860,3 ± 98,2) mg/day in the age of 7—10 and (777,9 ± 59,3) mg/day in eth age of 11—18. It is 1,2—1,6 times lower than the recommended norm. In teenagers, the calcium deficit in food is more often compared to preschool children.
Prevalence, clinical and prognostic value of polymorphism of genes II, V factors of blood coagulation and methylenetetrahydrofolate reductase in patients with chronic kidney disease
Authors: Pavlenko O. A. , Kolosovskaya T. A. , Sibireva O. F. , Khitrinskaya Ye. Yu. , Grankina V. Yu. , Kalyuzhin V. V.
Published: June 2020

The aim of the investigation was to study the prevalence, clinical and prognostic values of polymorphism of genes II, V factors of blood coagulation and methylenetetrahydrofolate reductase in patients with chronic kidney disease. Examination was performed on 90 patients with diabetic nephropathy (DN) and 180 patients with chronic glomerulonephritis (CG). In addition to complete clinical and instrumental examination accepted in specialised clinic, with the help of polymerase chain reaction diagnostics of polymorphism of the referred above genes (samples of genomic DNA were obtained from peripheral blood leukocytes) was conducted. It was found that the protrombogenic mutations under investigation which are detected in patients with DN and CG more often than in healthy subjects are associated with development of hypercoagulation syndrome and higher risk of renal failure.
Quality of life: actual of problem and characteristics quality of life children with bronchial asthma
Authors: Timoshina Ye. L. , Dugarova S. B.
Published: June 2020

The review includes data and some results of studying the quality of life for patients with bronchial asthma from domestic and foreign literature.
Ultrasonographicpotencial in detection of Acute Appendicitis
Authors: Piskunov V. N. , Zavadovskaya V. D. , Zavyalova N. G.
Published: June 2020

On the grounds of ultrasonography of 275 patients with suspected Acute Appendicitis (AA) the diagnosis was confirmed in 63 (22,9%) cases, it was true-positive results; in 3 (1,1%) cases of non-confirmed AA ultrasound findings were regarded as false-positive results. True-negative results of examination were obtained in 194 cases (70,5%) and false-negative results — in 15 cases (5,5%). The presence of rarevascularity of interior wall and clear visualization of vessels in mesentery of vermiform appendix is typical for congestive appendicitis. When phlegmonous appendicitis there are numerous vascular branches in interior wall blood stream of appendix: they make a picture of color «crown» in horizontal section and color «stripe» in longitudinal section. Gangrenous appendicitis is attached to few color spots in those parts of appendix wall which are not destroyed yet. Vascular pattern in adjacent intestinal loops predominates over vascular pattern of vermiform appendix. In case of empyema vermiform appendix vascular pattern in the wall is detected only in mesentery area. Vascular pattern of appendix is not detected in cases of appendicular infiltrate and periappendicular abscess unlike vascular pattern of adjacent intestinal loops which is rather intensified. The sensitivity of ultrasonography in AA detection was 80,7%, specificity — 98,4%, and accuracy — 93,4%. High index of diagnostic effectiveness of the method was obtained because of adoption of combining B-mode with both Colour Doppler and Power Doppler methods.