bluuebunny/crossref_metadata_2025 huggingface dataset:
Dynamic changes of enhancer and super enhancer landscape in degenerated nucleus pulposus cells
Authors: Li Guowang , Kang Yuxiang , Feng Xiangling , Wang Guohua , Yuan Yue , Li Zhenhua , Du Lilong , Xu Baoshan
Published: April 2023

Inflammatory cascade and extracellular matrix remodeling have been identified as pivotal pathological factors in the progression of intervertebral disc degeneration (IDD), but the mechanisms underlying the aberrant activation of transcription during nucleus pulposus (NP) cell degeneration remain elusive. Super-enhancers (SEs) are large clusters of adjacent lone enhancers, which control expression modes of cellular fate and pathogenic genes. Here, we showed that SEs underwent tremendous remodeling during NP cell degeneration and that SE-related transcripts were most abundant in inflammatory cascade and extracellular matrix remodeling processes. Inhibition of cyclin-dependent kinase 7, a transcriptional kinase–mediated transcriptional initiation in trans-acting SE complex, constricted the transcription of inflammatory cascades, and extracellular matrix remodeling–related genes such asIL1βandMMP3in NP cells, meanwhile, also restrained the transcription ofMmp16,Tnfrsf21, andIl11ra1to retard IDD in rats. In summary, our findings clarify SEs control the transcription of genes associated with inflammatory cascade and extracellular matrix remodeling during NP cell degeneration and identify inhibition of the cyclin-dependent kinase 7, required for SE-mediated transcriptional activation, as a therapeutic option for IDD.
Development and validation of playful didactic resources for the prevention of accidents in childhood
Authors: Chagas da Costa Vânia , Queiroz do Nascimento Maria Eduarda , De Lima Nascimento Monique Maria , Rodrigues Alves da Silva Laryssa , Batista Ferreira e Pereira Emanuela , Bezerra de Melo Leão Deuzany
Published: April 2023

Objetivo: Desenvolver e validar recursos didáticos lúdicos para prevenção de acidentes comuns na infância para escolares de 4 e 5 anos da educação infantil. Métodos: Trata-se de um estudo de desenvolvimento e validação de recursos didáticos lúdicos, do tipo pesquisa metodológica, desenvolvida em duas etapas, sendo a primeira a construção de recursos didáticos lúdicos e a segunda etapa a validação do material por juízes especialistas. Resultados: Foram elaborados um roteiro de história, duas paródias, uma atividade ilustrada, um jogo e duas brincadeiras que abordaram temáticas de prevenção de acidentes comuns na infância, quedas e queimaduras, sendo posteriormente avaliados por onze juízes especialistas na área da saúde da criança e da educação infantil que classificaram os recursos didáticos lúdicos como ferramentas eficazes para uso em intervenções educativas com escolares da educação infantil para prevenção de acidentes comuns na infância. A média geral de todos os domínios avaliados mostrou 98% de concordância. Conclusão: Este estudo evidenciou a relevância da validação dos recursos didáticos lúdicos para serem utilizados em ações educativas planejadas com qualidade, propiciando às crianças o conhecimento sobre prevenção de acidentes comuns na infância.
Permanent education in nursing care in the maintenance of the central venous catheter of peripheral insertion
Authors: Silva Klebson Rodrigues da , Neves Lais Gabriela da Silva , Silva Luciane Fayal da , Silva Marcos José Risuenho Brito , Simor Alzinei
Published: April 2023

Objective: To report a continuing education activity on the maintenance of PICC developed by nurses and nursing students in an oncology hospital.  Methods: This is a study of the type of experience report based on Problematization following the five stages of the Maguerez Arch. In the observation, the use of PICC was verified in the hospital therapy protocol, and the complexity of its use was considered, focusing on the need for updating on care. For the theorization, a literature review was performed. In the fourth stage, a permanent education was defined as an approach with professionals. The activity occurred with the realization of a Quiz and explanation of the content with the didactic material produced. Results: Quiz questions and material targeted activity. The team demonstrated to know the answers, and it was up to the mediator to complement the subject. The activity has given way to the standardization of catheter procedures and care, in addition to the sharing of experience among professionals. Conclusion: In the use of PICC, improving care promotes the prevention of complications and effective care. The continuity of developing the theme is necessary, because the improvement of the professional needs to be continuous.
Early identification and initial treatment of sepsis by emergency nurses
Authors: Bezerra Nayara Kalila dos Santos , Silva Paulo Sérgio da , Maciel Jackeline da Costa , Carvalho Fabíola Christian Almeida de , Caldart Raquel Voges
Published: April 2023

Objetivo: Identificar o conhecimento dos enfermeiros atuantes no setor de emergência sobre a identificação e tratamento inicial da sepse. Métodos: Estudo descritivo, transversal, quantitativo, desenvolvido na emergência de um hospital público de Roraima, com 25 enfermeiros. Os dados sociodemográficos, ocupacionais e de conhecimento dos enfermeiros sobre sepse foram coletados por meio de um formulário estruturado online através do Google Forms e analisados utilizando-se estatística descritiva por meio do programa Statistical Package for the Social Sciences (SPSS) versão 20.0. Resultados: Dentre os participantes, 76,0% relataram não terem recebido treinamento sobre sepse e não possuírem conhecimento sobre a existência de protocolos de sepse na instituição. Quanto às questões específicas sobre sepse, 68,0% apresentaram conhecimento desatualizado sobre a definição atual e os sinais clínicos da sepse. O manejo inicial de sepse, tempo ideal para administrar a primeira dose do antibiótico e iniciar antibiótico de amplo espectro, foram as questões que obtiveram melhores percentuais de acerto, com 88,0% e 80,0%, respectivamente. Conclusão: Verificou-se que há lacunas no conhecimento dos enfermeiros da emergência sobre a identificação e o tratamento precoce da sepse, justificando a necessidade urgente de realização de capacitações e implantação de protocolos clínicos sobre o tema na instituição.
Evaluation of anthropometric indicators and food consumption in patients with type 2 diabetes mellitus
Authors: Araújo Rafael do Nascimento , Aguiar Antônio Henrique Braga Martins de , Azevedo Yuri Sandro de Lima , Cantanhede Lucas Antônio de Oliveira , Braga Lorena Carvalho , Silva Andréa Cristina Oliveira
Published: April 2023

Objective: To evaluate the anthropometric indicators and food consumption of people with Type 2 Diabetes Mellitus treated at a Basic Health Unit in the city of São Luís, Maranhão. Methods: This is a cross-sectional and descriptive study with a quantitative approach conducted with 36 patients who have Type 2 Diabetes Mellitus, treated at a Basic Health Unit in the capital city of Maranhão. Semi-structured forms were used to collect sociodemographic and anthropometric data, as well as related to eating habits. The analyses were performed using descriptive statistics, with data represented as mean, frequency and their respective standard deviations, in addition to Pearson's correlation test between the quantitative variables. Results: The sample was mostly represented by women (54.4%), older adults (59.6%), sedentary people (63.1%), who had high abdominal obesity (80.4%), ingested a low amount of fiber (93.5%) and consumed a large amount of protein (67.4%), saturated fat (69.6%) and sucrose (57.5%). Conclusion: Factors such as inadequate weight and unregulated eating habits can represent risks for glycemic control and contribute to worsening of Diabetes Mellitus.  
Descritores: Diabetes mellitus. Estado nutricional. Consumo de alimentos.
Health professionals' knowledge about patient safety: an integrative review
Authors: Abreu Ingrid Moura de , Avelino Fernanda Valéria Silva Dantas , Mendes Priscila Martins , Rocha Daniel de Macedo , Tavares Ana Paula Mousinho , Carvalho Igho Leonardo do Nascimento , Pierot Esteffany Vaz
Published: April 2023

Objective: To analyze, in the literature, health professionals' knowledge about patient safety. Methods: An integrative review with searches and selection in five electronic databases: MEDLINE, CINAHL, Web of Science, LILACS and BDENF, using controlled and non-controlled descriptors indexed in the DeCS and MESH vocabularies. Primary studies with no time or language restrictions were included, with exclusion of duplicates, editorials, theses and dissertations. For analysis and synthesis purposes, the level of evidence classification based on the Oxford Centre for Evidence-based Medicine recommendations and the descriptive methods was used. Results: Eleven articles with level of evidence 2C and developed in the national and international contexts were selected. The level of general knowledge about patient safety among health professionals was considered low, involving significant limitations in the understanding of concepts and definitions, as well as in the application of theoretical assumptions in the care practice. In the categories investigated, certain variation of this knowledge level was observed. Conclusion: There are important gaps in health professionals' knowledge about patient safety, with the subjects presenting low knowledge levels. Therefore, permanent education stands out as a strategy to promote improvements.
The mental health of Basic Health Unit nurses in times of pandemic
Authors: Alves Letícia Jacome , Barros Francisco Railson Bispo de , Cardoso Andrea dos Santos
Published: April 2023

Objective: To know the mental health of nursing professionals from a Basic Health Unit exclusively for patients with COVID-19 in the municipality of Boa Vista, Roraima. Methods: This is an exploratory and descriptive study, with a qualitative and quantitative approach, carried out with 19 nursing professionals. The data was collected between April and June 2022, using a semi-structured script of 21 mixed questions. The interviews were analyzed using Bardin's method and the quantitative variables were submitted to the Statistical Package for the Social Sciences (SPSS) version 23.0. Results: The issue of stressors that interfere with mental health, associated with work activity during the COVID-19 pandemic, became evident. These factors had as a consequence the prevalence of psychological alterations such as fear, insecurity, anxiety, and stress. Concerning the diagnoses of mental disorders, anxiety and depression were the ones that stood out. Physical activity, psychotherapy, and religion were the coping measures adopted by the professionals interviewed. Conclusion: During the pandemic and their work practice, the professionals in this study were exposed to various stressors, developed psychological pathologies, but sought to maintain some level of mental health.
Semioapp application validity for teaching skin semiology in older adults
Authors: Ribeiro Yonara Cristiane , Louro Thiago Quinellato , Barreto Ana Claudia Mateus , Gobatto Mariângela , Palermo Matheus Vidal Azevedo , Silva Carolina Vilela Santos da
Published: April 2023

Objetivo: Validar o conteúdo e aparência de um aplicativo voltado para o ensino do exame físico da pele da pessoa idosa na graduação em enfermagem. Método: Trata-se de uma pesquisa metodológica aplicada para validação de conteúdo do aplicativo Semioapp, que tem como tema o exame físico da pele da pessoa idosa. A mesma foi aprovada pelo Comitê de Ética em Pesquisa da Universidade Federal Fluminense, e participaram 27 juízes. Para análise dos dados, utilizaram-se a estatística descritiva e o cálculo do Índice de Validade de Conteúdo. Foram considerados validados os itens que obtiveram nas respostas índice de concordância entre os especialistas maior ou igual a 0,78. Resultados: Participaram 27 juízes, graduados em enfermagem, sendo que 14,8% eram doutores, 11,1%, mestres, 59,3%, especialistas e 14,8%, especializandos. O perfil sociodemográfico dos participantes demonstra que houve uma participação majoritária de 88,9% da figura feminina, enquanto que, na masculina, houve 11,1%. A média dos blocos avaliativos foi de 88,1%. Em relação ao segundo bloco, a média foi de 79%, e o terceiro bloco obteve média de 82,4%. O IVC-G total foi de 86%. Considerações finais: O objetivo foi alcançado, e o Semioapp, validado, pois obteve um resultado acima da média considerada aceitável nesta pesquisa.
Nursing care for acute coronary syndrome in an emergency care unit
Authors: Agostini dos Santos Thábata Larissa , Matos Eliane , Chiodelli Salum Nádia Maria , Da Silva de Souza Sabrina , Lins Pereira Cinthya Maria , Honório Locks Melissa Orlandi
Published: April 2023

Objetivo: Verificar a conduta do enfermeiro no atendimento ao paciente com síndrome coronariana aguda e identificar quais os cuidados de enfermagem realizados ao paciente em unidades de pronto atendimento. Métodos: Estudo qualitativo, exploratório, descritivo, organizado e guiado conforme o modelo de Design Instrucional Contextualizado, na etapa de análise. A coleta de dados ocorreu de janeiro a abril de 2019, em Unidade de Pronto Atendimento, por meio de entrevista semiestruturada com 19 enfermeiros de um município do litoral norte de Santa Catarina no sul do Brasil e os dados foram submetidos à análise temática. Resultados: Emergiram três categorias: “identificando sinais e sintomas da síndrome coronariana aguda”, “definindo as condutas” e “proposta de cuidados de enfermagem”. Os enfermeiros baseiam a avaliação nos sinais clínicos e sinais vitais e em suas experiências, destacam a realização do eletrocardiograma, restrição de esforço físico e preocupação com os cuidados realizados na sala de emergência até estabilização do caso, ou transferência para o hospital de referência. Conclusão: A conduta dos enfermeiros não segue um padrão de cuidados resultando na variação do atendimento. Foram propostos os cuidados e estes corroboram com a literatura e são primordiais no manejo aquedado da síndrome coronariana aguda na urgência e emergência.
Experience report of nursing students in a supervised curricular internship in the COVID-19 pandemic context
Authors: Barbosa Amanda Conrado Silva , Ferreira Hanna Cristina , Oliveira Liodany Rutherlem dos Santos , Nicácio Leticia Ferreira França , Oliveira Lucimar Borges de , Carmo Yasmin Chagas do , Pardini Rafaela Dias
Published: April 2023

Objective: To report Nursing students' experience during a curricular internship in a hospital environment in the COVID-19 pandemic context. Methods: This is an experience report, of a descriptive-reflective nature, about the experiences of four students attending the 9th semester of the Nursing course at a Public University from the state of Minas Gerais, during the Supervised Curricular Internship in a hospital environment in the COVID-19 pandemic context. Results: The initial practice in a hospital environment generated insecurity in the students, due to fear in the face of the current scenario of increased COVID-19 cases. The students experienced frustration in not providing dignified care to these patients and fear of contaminating themselves and being a means of spreading the virus to others. In addition, some students presented symptoms suggestive of mental distress. Conclusion: The leading role of the Nursing team was observed by the students when they witnessed, in their everyday lives, the set of actions provided for the assistance and care of patients aggravated by COVID-19. Despite the professionals' work overload and non-guarantee of rest between shifts, there was care continuity.
Family doctors’ perception of violence against women
Authors: Silva Joaquim José Marques da , Mesquita Eliana Mendes , Campelo Viriato
Published: April 2023

Objective: This study aimed to evaluate the perception of family doctors about violence against women. Methods: This is a cross-sectional study, developed with 158 doctors from the Family Health Strategy of Teresina/Piauí, from March to April 2019, through a questionnaire adapted from the Social Perception Indicator System of the Institute of Applied Economic Research. Results: The findings indicate that male doctors, specialists, with over 25 years of training and more than 60 years of age, have a perception of violence against women based on the patriarchal model, as a problem of an intimate nature and of blaming of the woman. Conclusion: Medical training is necessary to conduct a care practice for women in situations of violence, giving them a reception guided by the social health model.
Awareness of Radiation Dose and Incurred Risk Among Clinicians at a Tertiary Care Hospital in Bahrain
Authors: Khalifa Mazna Al , Alghanem Salah , Mohamad Abdulraoof AM
Published: April 2023

Background & Objectives: Literature has raised concern about the inadequate knowledge of radiation dose and risk among referring clinicians for radiological procedures. Therefore, we surveyed to assess the knowledge of radiation protection and dose assessment among clinicians. Methods: A cross-sectional web-based survey where the link was circulated to 87 clinicians who requested diagnostic radiological imaging. A validated questionnaire consisted of 20 multiple-choice questions divided into three sections, viz, demography, awareness of radiation risk, and knowledge of radiation dose, were asked to reply. Results: A total of 87 physicians from 15 different medical specialties were included in the analysis. Interns had the highest knowledge score in radiation protection (59.5%, P=0.198), while the dose assessment score was highest among radiologists (50.8%, P=0.013). The average knowledge of radiation protection was 43% ± 17%, and awareness of radiation dose was 30% ± 18%. Clinicians having experience >20 years were found with the least score (33.3%) of radiation protection knowledge, while those with <3 years of experience showed a better score (48%, P=0.064). Clinicians who claimed to be attending radiation protection courses regularly were found with better scores of knowledge (47.6%, P=0.340) and dose assessment (37%, P=0.161), although the difference was nonsignificant. Conclusion: The clinician’s knowledge of radiation protection and dose assessment is inadequate which could infer a propensity of the inappropriate use of radiation imaging. There is a substantial need for training/refresher courses to improve the knowledge of radiation dose and consequent risk in order to assure patient safety during radiological examinations. Keywords: Ionizing radiation, Radiation dose, Risk awareness, Radiological examination, Diagnostic imaging
Epithelioid Sarcoma of the Skull: A Differential Diagnostic Approach
Authors: Almasarei Hazem Muhammed , Saad Darine Helmy Amin , Tahoun Suad Muhammad Abu , Alsbahi Sufyan Sameer Sami , Shanbhag Nandan Maruti
Published: April 2023

Epithelioid sarcoma of the scalp as a primary site of origin is a rare occurrence a and has a broad differential diagnosis. The radiological features for each of the differential diagnoses are similar but sometimes can be very unique. The present case study provides relevance and significance in considering the possibility of primary epithelioid sarcoma while examining benign lumps with no skin ulceration or pain. The case report focuses on imaging features of epithelioid sarcoma while employing to describe the lesion using multimodality imaging in addition to Computer Tomography, early intervention in the form of complete excision of these tumours through surgery and primary repair when required. Adequate adjuvant treatment is needed following the excision, with the goal of preventing recurrences.
¿Piropo o Acoso Sexual Callejero? Un análisis jurídico con perspectiva de género
Authors: Valencia Duche Emilia Belén , Maldonado Ruiz Luis Mauricio
Published: April 2023

Mas de una mujer relata una experiencia donde uno o varios hombres se han dirigido a ellas expresándoles verbalmente o no verbal contenido sexual, sin que ellas lo permitan o lo reclamen, creando con ello la jerarquía poder sumisión. Esta situación la sociedad la ha venido aceptando, naturalizándola y normalizándola privando así a la mujer a vivir en un ambiente seguro, conociendo que todos tenemos derechos a vivir en un ambiente sano, el derecho a la vida, seguridad, derecho a la autonomía y a la libertad. El objetivo de este artículo es presentar la investigación sobre la afectación social de la mujer en espacios públicos que provoca el “piropo” o actos de naturaleza sexual hacia la mujer como un acoso sexual callejero. Con el propósito de identificar como maneja jurídicamente el Ecuador este tipo de vulneración de derechos de la mujer en referencia de otros países. Finalmente, se analiza y se estudia los posibles remedios legales para sancionar y retraer estos comportamientos contra la integridad de la mujer buscando así que sea tipificado el acoso sexual callejero.
El turismo como recurso generador de crecimiento y desarrollo económico
Authors: González Soriano Franklin Javier , Ortiz Choez Gustavo Guillermo , Morán Quijije Eduardo Erasmo
Published: April 2023

El turismo es uno de los sectores económicos con mayor crecimiento en el mundo. Se considera que la industria del turismo se encuentra entre la más grande del mercado, visto como un canal de desarrollo regional de acuerdo con la innovación de actividades en el ámbito económico y teniendo un impacto positivo en la generación de empleos, la balanza de pagos, renta bruta y la producción. Sin embargo, el turismo también puede tener un impacto negativo principalmente en el medio ambiente debido a su crecimiento, generando deterioro en el mismo. En tal sentido, el medio ambiente debe blindarse para lograr un crecimiento del turismo de manera controlado, principalmente en los sitios naturales y patrimonios culturales e históricos. De acuerdo con esto, se sabe que el turismo sostenible tiene tres aspectos interconectados: ambiental, sociocultural y económico. La sostenibilidad implica permanencia, por lo que el turismo sostenible incluye el uso óptimo de los recursos, incluida la diversidad biológica; minimización de impactos ecológicos, culturales, sociales; y la maximización de los beneficios para la conservación y las comunidades locales. En el presente documento se expone el desarrollo económico generado por el turismo, así como también, la relación que existe entre la empresa y la conservación del medio ambiente, tomando en cuenta las oportunidades de empleo y producción que se obtienen con un turismo controlado y sostenible.
Educación superior libre de discriminación direccionado a estudiantes del tercer nivel
Authors: Vásquez Aguilar Douglas Vicente , Llamuca Baque Gerardo David , Morales Román Guillermo Ernesto , Vélez Vélez Sandra Monserrate
Published: April 2023

La educación se ha reconocido en todo el mundo como un derecho universal, y como tal, debe ser garantizado por cada Estado. En la educación superior, la brecha en el acceso y trato hacia la diversidad de la población estudiantil, aún sigue siendo muy marcada. Ecuador no escapa de esta realidad, la diversidad en su población ha subido la barra en la extinción de mecanismos de exclusión en el área educativa. El objetivo de la presente revisión consiste en compendiar lo relacionado a la discriminación en la educación superior ecuatoriana, especialmente a los estudiantes de tercer nivel. Para lo cual se desarrollará la discriminación por razones de género, económicas y la legislación nacional en pro de la libre discriminación a los estudiantes de la educación superior. La investigación se realizó bajo una metodología de tipo documental bibliográfica, bajo la modalidad de revisión. De la revisión se desprende que Ecuador es un país con una desigualdad marcada en el acceso y el trato discriminatorio a los estudiantes de educación superior, especialmente por razones de género y económicas. No obstante, se han logrado grandes alcances en materia de legislación y programas que ofrecen nuevas formas de gestión que permitan o garanticen la igualdad y la no discriminación de los diferentes grupos que intentan acceder y permanecer en estas instituciones. Uno de estos cambios radicales para el tercer nivel de educación superior es el proceso de admisión a las universidades públicas y privadas del país para el presente año, el cual ya no se realizará a través de las pruebas nacionales como en los anteriores años, sino que ahora cada institución educativa tendrá su propio proceso de admisión. Quedando por parte del estado monitorear que todo ese procedimiento se enmarque en la transparencia, eficiencia y en la ética, por ende, que se cumplan con los criterios de igualdad y no discriminación. Igualmente, se espera que los instrumentos legales no solo queden en el papel, sino que se cumplan a favor de la inclusión educativa y en contra de la discriminación.
Tratamiento con células madres en neonatos
Authors: Bravo Neira Alyssa Geslenny , Ormaza Barreto Alvaro Moisés , Choles Ortega Leonela Katiuska , Guaigua López Silvia Marcela
Published: April 2023

A pesar de los avances en el cuidado del bebé prematuro, varias complicaciones graves que conducen a secuelas significativas siguen siendo un desafío clínico. Displasia broncopulmonar (DBP), complicaciones gastrointestinales y lesión neurológica aún afectan a un gran número de lactantes, lo que lleva no sólo a mortalidad y morbilidad en cuidados intensivos neonatales (UCIN), sino también a la reducción a largo plazo en la calidad de vida. La terapia con células madres ha surgido como un potencial enfoque prometedor terapéutico en el manejo de las complicaciones comunes de prematuridad. La metodología utilizada para el presente trabajo de investigación, se enmarca dentro de una revisión bibliográfica de tipo documental. La técnica para la recolección de datos está constituida por materiales electrónicos, estos últimos como Google Académico, PubMed, entre otros, apoyándose para ello en el uso de descriptores en ciencias de la salud o terminología MESH. La información aquí obtenida será revisada para su posterior análisis. Las terapias con células madres son el futuro de la medicina, sin embargo, su manejo es delicado, y por ello debe haber protocolos estandarizados para su aislamiento, manipulación, expansión in vitro y administración. Hay diferentes tipos de células madres que se extraen de la medula ósea, cordón umbilical, tejido adiposo, piel, entre otros. Las terapias para su utilización en neonatos siguen controvertidas por la falta de evidencias solidas que avalen su uso, para la certificación de su eficacia. La gran ventaja de las terapias de células madres es su poder de regeneración, por su capacidad de dar origen a otras células, y que puedan recuperar anatómica y funcionalmente tejidos, órganos y sistemas, que en la actualidad conducen a enfermedades crónicas, como las que se puede presentar en neonatos.
Estrés y satisfacción laboral en gestores de una empresa de cobranza en Guayaquil, Ecuador
Authors: Quinto Reyes Génesis Paulett , Merchán Espinoza Bryan Daniel , Bastidas Bolaños Cecilia María
Published: April 2023

El estrés y la satisfacción laboral son factores que en la actualidad está afectando a los trabajadores en las diferentes ramas profesionales o áreas laborales que hay en el país. Estos factores junto con los problemas políticos y económicos generan malestares psicofisiológicos a los colaboradores de las empresas, entre ellos las empresas de cobranza. Por lo tanto, es importante identificar las problemáticas que se encuentran dentro del call center para mejorar los resultados de los colaboradores. El objetivo de la investigación fue determinar la relación entre el estrés laboral y la satisfacción laboral en los gestores de una empresa de cobranza de la ciudad de Guayaquil. La investigación fue de tipo cuantitativa, con diseño no experimental, transversal y alcance correlacional. Los instrumentos empleados fueron el Cuestionario de Satisfacción Laboral (SL-SPC) y la Escala de Estrés Laboral (OIT-OMS). Los resultados obtenidos demostraron que los niveles de estrés laboral en la mayoría de los gestores son bajos y se presenta un nivel alto en relación con la satisfacción laboral, dichos resultados también nos demuestran que existen factores de estrés a nivel bajo- medio que se deben tomar en cuenta. Como conclusión se determina que existe una correlación inversamente proporcional y poco significativa entre las variables, a menor nivel de estrés es mayor el nivel de satisfacción laboral, permitiendo verificar que las dimensiones de estrés laboral tienen alguna relación con las de satisfacción laboral aceptando la hipótesis alternativa.
Procesos infecciosos periodontales de origen endodóntico
Authors: Angulo Quiñónez Leonardo Fabricio , Montesdeoca Suárez Cesar Augusto , Mejia Gallegos Cesar Gerardo , Zurita Blacio Solange Melina
Published: April 2023

El termino infección hace referencia a la existencia y proliferación de microorganismos en el cuerpo. Las infecciones periodontales comprenden un grupo de enfermedades que, establecidas en la encía y las estructuras de soporte del diente, han sido generadas por determinadas bacterias, generalmente, provenientes de la placa subgingival, aunque igualmente podrían intervenir factores predisponentes del hospedador y microbianos que influyen contribuyen en su patogénesis. Los procesos patológicos que se desencadenan desde el interior del diente, también pueden invadir el desmodonte, y es allí donde entonces se podría constituir los procesos infecciosos periodontales de origen endodóntico. El objeto de adelantar el presente estudio nace de lo antes expuesto, ya que, si bien parece raro la incidencia de estos casos, se considera importante aportar información actualizada que contribuya con la ampliación de los conocimientos útiles para un mejor desarrollo profesional. La metodología investigativa se enmarca en una revisión bibliográfica. En los resultados se desarrollan acepciones, causas, síntomas y factores de riesgo de estas patologías. En definitiva, es posible sostener que los procesos infecciosos periodontales de origen endodóntico están referidos a un grupo de afecciones arraigadas en el periodonto, causadas por agentes bacterianos usualmente provenientes de la placa bacteriana, aunque también pueden intervenir otros de origen microbianos o predisponentes del hospedador que repercuten en su patogénesis.
Síndrome de fricción femoral patelar (SFP)
Authors: Tinoco Vaca Nelson Omar , Aragón Herrera Stalin Gabriel , Beltrán Bastidas Carlos Andrés
Published: April 2023

El dolor referido a la cara anterior de la rodilla con los movimientos de flexión (síndrome femoropatelar) es, sin duda, la causa más frecuente de consulta por dolor de esta articulación en adultos jóvenes (entre los 18 y los 40 años de edad), independientemente de que practiquen o no alguna actividad deportiva. La presente investigación contiene información de revisión bibliográfica de tipo documental. La técnica para la recolección de datos está constituida por materiales impresos y electrónicos estos últimos como Google Académico, Scielo, PubMed, entre otros. La fisioterapia busca reestablecer la funcionalidad del miembro afectado, por ello los ejercicios deben programarse con una frecuencia que posibiliten el progreso constante, ya que la sintomatología de cada paciente puede ser diferente y por ello el tratamiento debe ser personalizado y diseñado exclusivamente para cada paciente. Las plantillas o soportes plantares mejoran en el corto plazo el síndrome femoropatelar, ya que sus efectos son similares a la fisioterapia, los mejores soportes son los fabricados a medida. En cuanto a la terapia farmacológica conservadora se encuentran los antinflamatorios no esteroides (AINES) en cuanto a manejo del dolor e inflamación de la zona afectada, sin embargo, la fisioterapia, así como los soportes plantares han arrojado mejores resultados.
Estimation of short-term settlements of MSW landfill materials using shear wave velocity
Authors: Kola Nagendra , Roy Debasis , Chakraborty Debarghya
Published: April 2023

Limited availability of simple yet adequately validated tools for estimating the deformation potential of municipal solid waste (MSW) material poses difficulty in planning and managing landfill operations. Estimation of settlement of MSW landfills has remained a challenge because of heterogeneity and time-varying mechanical behavior of MSW materials and difficulty of extracting representative samples and reconstituting them for laboratory testing. An empirical correlation is proposed here for estimating the short-term settlement of landfill materials. The relationship was developed by calibrating laboratory data from axial (1D) compression and consolidated drained triaxial tests against field-measured shear wave velocities from five landfill sites with varied waste compositions. The correlation was validated against three full scale load tests; one obtained in this research and two reported by others, and a field compaction study from a fourth landfill. Although the proposed correlation was more accurate than an alternative developed earlier, overall it underestimated settlements by about 12%. The proposed relationship could therefore provide a conservative guidance in MSW landfill design and operation.
Identifikasi Faktor yang Berpengaruh terhadap Penentuan Pemenang Lelang Jasa Konstruksi
Authors: Nurhayati Nurhayati , Agus Irzal
Published: April 2023

Pelaksanaan proyek konstruksi banyak melibatkan berbagai pihak dalam hal interaksi dan koordinasi. Agar keinginan pemilik dapat terealisasi maka pemilik akan memilih kontraktor yang berkualifikasi untuk melakukan pembangunan melalui sebuah proses pelelangan. Ada beberapa faktor yang berpengaruh untuk dapat memenangkan sebuah pelelangan. Penelitian ini bertujuan untuk mengetahui faktor-faktor yang mempengaruhi pemenang lelang jasa konstruksi pada proyek pemerintah Kabupaten Buton yang melingkupi tiga (3) proyek pada Dinas Pekerjaan Umum & Tata Ruang, Dinas Pendidikan serta Dinas Perhubungan. Objek penelitian dari ketiga dinas tersebut yaitu berupa proyek gedung. Kuisioner diberikan kepada para kontraktor kemudian data dianalisis menggunakan SPSS yaitu analisis regresi, uji model, uji F, uji T dan autokorelasi. Dari hasil analisis diperoleh tiga (3) faktor dominan yang mempengaruhi pemenang lelang jasa konstruksi yaitu pekerjaan yang disubkan (X2), hubungan baik antara owner dan kontraktor (X26) dan sistem komunikasi di proyek (X35).
Analisis Pemilihan Rute dengan Logika Fuzzy
Authors: Kartika Atikah , Nahdalina Nahdalina
Published: April 2023

Pelaku perjalanan memiliki persepsi yang berbeda dalam menentukan arah rute perjalanan. Tujuan dari penelitian ini memprediksi pemilihan rute berdasarkan rute tercepat dengan mempertimbangkan variabel waktu tempuh, kecepatan rata-rata, dan derajat kejenuhan jalan. Metode yang digunakan terdiri dari kombinasi pemilihan rute dan pembobotan rute. Pembobotan rute tersebut dihitung menggunakan logika fuzzy metode Mamdani dengan menghasilkan bobot yang paling rendah. Penelitian dilakukan di Kabupaten Bogor dengan 1 asal dan 3 tujuan yang dihubungkan oleh 25 ruas jalan dan 19 titik simpul. Analisis yang dilakukan terdiri dari 2 skenario. Hasil analisis menunjukan bahwa rute yang dihasilkan berdasarkan skenario 1 dan skenario 2 berbeda. Hasil skenario 1 menggunakan waktu tempuh dan DS untuk asal 1 ke tujuan 2 melalui simpul 1-10-11-7-5-6-9-2 dengan nilai pembobotan sebesar 0,186, asal 1 ke tujuan 3 melalui simpul 1-10-12-13-14-3 dengan hasil pembobotan sebesar 0,224, dan asal 1 ke tujuan 4 melalui simpul 1-10-12-15-16-18-19-4 dengan hasil pembobotan sebesar 0,291. Sedangkan hasil skenario 2 kecepatan rata-rata dan DS untuk asal 1 tujuan 2 melalui simpul  1-10-11-7-8-9-2 dengan hasil pembobotan sebesar 0,198, asal 1 tujuan 3 melalui simpul 1-5-6-9-8-13-14-3 dengan hasil pembobotan sebesar 0,222, dan asal 1 tujuan 4 melaui simpul 1-5-6-9-8-13-12-15-16-17-19-4 dengan hasil pembobotan sebesar 0,208. Tingkat validasi program mencapai 99,91%.
Studi Analitis dan Eksperimental Mekanisme Slip-Kritis Sambungan Struktural Baut Baja
Authors: Sulandari Noek , Pranata Yosafat Aji , Kristianto Anang
Published: April 2023

Letak geografis Indonesia menjadikan Indonesia sebagai negara yang rawan bencana gempa baik tektonik maupun vulkanik. Standar Nasional Indonesia (SNI) 1729:2015 mensyaratkan sambungan baut bangunan baja dengan tinggi lebih dari 38 m, harus menggunakan baut mutu tinggi (High Strength Bolt – HSB) dengan pra-tarik. Sambungan baut kencang pas (snug tight) dan sambungan baut dengan pra-tarik, secara kasat mata tidak berbeda. Perbedaan akan terjadi saat sambungan dibebani yaitu untuk sambungan dengan pra-tarik, slip antar pelat yang disambung sebagai akibat ukuran lubang baut yang lebih besar dari diameter baut baru akan terjadi saat kuat batas slip terlampaui. Penelitian ini bermaksud mengamati kekuatan dan perilaku sambungan baut dengan pra-tarik terhadap peningkatan beban. Analisis dilakukan menurut SNI 1729:2015, validasi data melalui uji eksperimental menggunakan benda uji pelat BJ37 yang dibebani aksial tarik konsentris. Sambungan menggunakan HSB-A325 M12, lubang standar dengan persiapan permukaan kelas A. Pemberian pra-tarik baut dengan cara putar mur (turn-of-nut). Hasil pengujian menunjukan kuat batas slip (Pslip) 37,998 kN, nilai ini 5,7% lebih tinggi dibanding hasil analitis sebesar 35,94 kN. Setelah tercapai kuat batas slip, sambungan tetap dapat menerima pembebanan dengan mekanisme pengalihan gaya tumpu dan mencapai kuat batas sambungan (Pu) sebesar 50,197 kN, yang berarti masih dapat menerima peningkatan beban 32% setelah slip terjadi. Putar mur (turn-of-nut) salah satu metode yang direkomendasikan SNI 1729:2015, merupakan cara yang cukup sederhana untuk pemberian pra-tarik karena tidak diperlukan alat khusus dan gaya pra-tarik minimum yang disyaratkan dapat dipenuhi dengan tercapainya Pslip hasil eksperimen tidak lebih rendah dibandingkan dengan hasil analisis
VERNADITE AS A METABOLIC PRODUCT OF MICROORGANISMS. MINERALOGICAL SPECIMENS FROM THE EARTH SCIENCE MUSEUM
Authors: Gromalova Natalya , Chekhovich Petr
Published: April 2023

Brief information is given about the samples of vernadite from the mineralogical collection of the Earth Science Museum, which were passed for display at the exhibition organized for the anniversary of V.I. Vernadsky. The history of the discovery and studying of vernadite and features of its chemism, modern concepts of its crystal structure, genesis as well as some practical applications are addressed. Attribution of the exhibition samples as vernadites is questionable due to the lack of information about their instrumental diagnostics.
RUSSIAN MICROBIOLOGISTS-NATURALISTS, CONTEMPORARIES AND INTERLOCUTORS OF V. I. VERNADSKY: ECHOES OF THEIR MEETINGS
Authors: Kolotilova Natalia
Published: April 2023

Brief information is given about several Russian microbiologists - naturalists whose names are found on the pages of V.I. Vernadsky’s diaries. Despite the variety of topics, their works always found hot reaction of V.I. Vernadsky. The knowledge of these materials helps one to understand the evolution of the scientists’ ideas, trends of the development of science.
“ANTI-MALTHUSIAN CONCEPTION, NOT A LIMITS TO GROWTH CONSTRUCT” (based on the proceedings of the International Conference at the Schiller Institute dedicated to V.I. Vernadsky)
Authors: Snakin Valeriy , Likhacheva Elena
Published: April 2023

The proceedings of the conference “The Physical Economy of the noösphere: Reviving the Heritage of Vladimir Vernadsky”, organized by the International Schiller Institute in honor of the 160th anniversary of Vladimir Vernadsky’s birth on 12 November, 2022, are presented. The participants stressed the great importance of Vernadsky’s doctrine in the development of modern civilization, from the standpoints of both strengthening international cooperation and the growth of productive forces. Some of the speakers noted the greater value of the anti-malthusian approach for humanity as compared to the construction of limits to growth
JOHN MAXWELL COETZEE’NİN İSA ÜÇLEMESİNDE MÜLTECİLİK VE TRAVMA
Authors: BARTAMAY Münevver
Published: April 2023

Mültecilik başlı başına bir travma olmakla birlikte, dönüşü zor bir durum olduğundan mültecilik travmasının üstesinden gelmek mülteci için neredeyse imkansız bir durumdur. Mültecinin memleketten ayrılmasını bebeğin anne rahminden ayrılmasına benzeten Salman Akhtar “sürgün”ün dilbilimsel olarak mülteciyle eş değer olmasının altını çizer. Bir yetişkin için mültecilik deneyimi önceki yaşantısının rahatlığına ya da zorluğuna göre etki bırakır; refah seviyesi yüksek bir hayatı terk etmek zorunda kalan birine mültecilik çok zor gelecektir. Buna bir de kamp hayatının çetrefilli deneyimi ilave edilirse depresyon yaşaması ve erken yaşlanması kaçınılmaz olur. Kişi, daha zor bir hayattan geçmişse ve iltica edilen ülkenin refahı daha yüksekse bu yeni bir hayat şansı da olabilir. Ancak bir grup var ki onlar için mültecilikte değişken refah ya da yoksulluk değildir; onlar için en önemli eksiklik anne-baba eksikliğidir: bu grup mülteci çocuklardır. Bu çalışmada savaşların neden olduğu travmalara maruz kalıp mülteci olmak durumunda kalan yetim bir çocuğun hikâyesi incelenecek ve mülteciliğin sebep olduğu travmadan sonuçlanan baş edilmesi zor durumlar irdelenecektir.
Product placement as an effective marketing tool
Authors:   https://www.elibrary.ru/item.asp?id=50436735, Иванова А.А.
Published: April 2023

In this study, the product placement technology is considered as a key marketing element of the modern market economic system. In the process of studying this phenomenon, the author comes to the conclusion that today product placement technology is a full-fledged, and often much more effective alternative to classical direct advertising. Nevertheless, at the moment in Russian marketing practice, this technology is often regarded by potential customers as a kind of secondary (compared again with direct advertising) a way of communicating with the target audience.
Enterprise reverse logistics management
Authors:   Российский университет кооперации, Рыжова И.О. , Смирнова А.В. ,   Российский университет транспорта, Мухина И.И. ,   Российский университет транспорта
Published: April 2023

The article considers the management of reverse flows on the example of LLC «Customer Opt», which operates under the brand UPMARKET (marketplace). The processes of moving cargo in the forward and reverse directions (return flows) are analyzed and conclusions are drawn about the need to select the most appropriate rolling stock to optimize the cost of transportation and build ring routes, through which it is possible to combine direct and reverse flows of goods in a single route
Promising tools for achieving the goals of regional economic policy
Authors:   Финансовый университет при Правительстве Российской Федерации, Никонорова А.В.
Published: April 2023

The article studies the main objectives of the national regional policy implementation with regard to modern realities. Goals and instruments that are able to achieve them become the subject for adjustment in accordance with changes in the external environment, trends in technology development, results of scientific and technological progress. New opportunities arise with the time, they bring more efficient and less resource-intensive solutions for the set goals and their corresponding tasks. All innovations should undergo additional analysis for their compliance with the interests of society and contribute to improving the lives of the population. The instruments for achieving goals are studied from the perspective of current trends in development of information technologies. The main instruments for implementing the goals of the regional economy are highlighted, special attention is paid to exploring solutions that are most promising in conditions of digitalization. Improvement of the instruments used for regional economy regulation contributes to the expansion of opportunities for economic growth of the region, increasing the level of manageability of economic systems, increasing the quality of life of the population, contributes to accelerating the pace of socio-economic development of the region. The actualization of methods for achieving the goals of the regional economy with regard to the modern results in scientific and technological progress, contributes to intensification in socio-economic development of the region, expands possibilities for influencing the factors that accelerate such development. Special attention is paid in the article to the study of the most efficient usage of the region’s resources.
Fungi on bean seeds obtained from growers in Isparta province
Authors: MERTOĞLU Şehnaz , HATAT KARACA Gürsel
Published: April 2023

The fungal load of seeds is among the factors related to seed quality. Seed-borne fungi can cause significant crop losses and may produce mycotoxins, which are harmful to human health. This study aimed to determine the seed-borne fungi of bean, which is among one of the most important crops cultivated in Isparta province. Seed samples from the 2015-2016 vegetation period, obtained from bean growers in Isparta province were used in this study. The fungal load of randomly selected 200 seeds were investigated by blotter and agar methods and prevalence and infestation rates of the fungi were determined. As a result, 41 species of fungi belonging to 26 genera were determined on 62 seed samples. The blotter method yielded 25 genera while 20 genera were determined by the agar method. Alternaria, Aspergillus, Cladosporium, Fusarium, Penicillium and Rhizopus species were the most common fungi found on almost all of the samples, for both methods. Infestation rates of these fungi were also high on bean seeds. Prevalence and infestation rates of the fungi were generally higher in the blotter method, except for Fusarium and Verticillium species that were determined on the seed samples in higher frequencies by the agar method. Absidia, Arthrinium, Epicoccum, Nigrospora, Scopulariopsis and Stachybotrys species were determined only by the blotter method, while Seimatosporium sp. was found by the agar method. Alternaria, Fusarium, Rhizoctonia, Stemphylium and Verticillium species are known as pathogenic fungi and may cause diseases on bean plants. Aspergillus and Penicillium species are saprobic fungi producing mycotoxins, so their presence on the seeds is also important.
Classical solution of a problem for a system of equations from mechanics with nonsmooth Cauchy conditions
Authors: Korzyuk V. I. , Rudzko J. V.
Published: April 2023

In this article, we study a mixed problem in a quarter-plane for one system of differential equations, which describes vibrations in the string from viscoelastic material, which corresponds to the Maxwell model. At the bottom of the boundary, we pose the Cauchy conditions, and one of them has a discontinuity of the first kind at one point. We set a smooth boundary condition on the lateral boundary. We derive the Klein – Gordon – Fock equation for one function of the studied system. We use the method of characteristics to build the classical solution as a solution of some integral equation. We prove the uniqueness and establish conditions under which a piecewise smooth solution exists. The Cauchy problem is considered the system’s second function. We determine the conditions under which the solution of the system has sufficient smoothness