bluuebunny/crossref_metadata_2025 huggingface dataset:
Modern technologies in the formation of quality and consumer properties of flour confectionery
Authors:   Department of Commodity Science and Goods Examination, International Institute of Economics and Linguistics, Irkutsk State University, Svyatkina L.I. , Andrukhova V.Ya. ,   Department of Commodity Science and Goods Examination, International Institute of Economics and Linguistics, Irkutsk State University
Published: July 2022

The consumer preferences in the city of Irkutsk regarding flour confectionery products have been identified. When choosing cookies, the majority of respondents start from the product composition and price. Based on organoleptic and physico-chemical analysis, it was found that the studied samples of oatmeal cookies meet the requirements of GOST 24901-2014. However, the regulatory framework for solving the problem of identifying the ingredients declared in the recipe is lagging behind. A formulation for a new flour confectionery product has been developed. It is a butter chocolate sandwich cookie with a layer of marshmallows and a filling of strawberry jam. The new cookie type can compete with analogues due to a lower energy value and useful properties.
On the requirements of the technical regulation of the Customs Union 015/2011 “On the Safety of Grain” for the identification of grain
Authors:   Plekhanov Russian University of Economics, Oshmarina A.G. , Agapkin A.M. ,   Plekhanov Russian University of Economics
Published: July 2022

Grain and its processed products are an integral part of economic development and stable and safe functioning of the food market. It is necessary to supply high-quality grain for sale, in respect of which the manufacturer must comply with all the requirements of the current legislation of the Russian Federation. The state controls the quality according to Technical Regulations of the Customs Union 015/2011 “On the safety of grain”, which establishes mandatory requirements for grain and procedures related to grain and processed products for their circulation on the territory of the EAEU Customs Unio
A Practical Guide to Genetic Testing for Kidney Disorders of Unknown Etiology
Authors: Aron Abraham W. , Dahl Neera K. , Besse Whitney
Published: July 2022

Genetic testing is increasingly used in the workup and diagnosis of kidney disease and kidney-related disorders of undetermined cause. Out-of-pocket costs for clinical genetic testing have become affordable, and logistical hurdles overcome. The interest in genetic testing may stem from the need to make or confirm a diagnosis, guide management, or the patient’s desire to have a more informed explanation or prognosis. This poses a challenge for providers who do not have formal training in the selection, interpretation, and limitations of genetic tests. In this manuscript, we provide detailed discussion of relevant cases in which clinical genetic testing using a kidney gene panel was applied. The cases demonstrate identification of pathogenic variants for monogenic diseases—contrasting them from genetic risk alleles—and bring up diagnostic limitations and diagnostic utility of these tests in nephrology. This review aims to guide clinicians in formulating pretest conversations with their patients, interpreting genetic variant nomenclature, and considering follow-up investigations. Although providers are gaining experience, there is still risk of testing causing more anxiety than benefit. However, with provider education and support, clinical genetic testing applied to otherwise unexplained kidney-related disorders will increasingly serve as a valuable diagnostic tool with the potential to reshape how we consider and treat many kidney-related diagnoses.
Expanding Effective Behavioral Health Literacy Programs to Address Farm Stress
Authors: Eschbach Cheryl , Cuthbertson Courtney , Shelle Gwyn , Bates Ronald
Published: July 2022

Attention to stress and mental health among agricultural producers has increased over recent years, and Cooperative Extension has been active in offering educational workshops and resources to agricultural audiences. This article describes the process and effectiveness of expanding two (university) Extension farm stress management programs to Cooperative Extension in other states through a national Farm Stress Management Summit. The two-day training Summit provided deeper knowledge about farm stress issues and prepared Extension professionals to offer behavioral health programs in their own communities and respective states. Evaluation findings highlight effective aspects of the Summit and next steps.
Synthesis, Characterization and Antimicrobial Activity of N-Pyridin-3-yl-benzenesulfonamide
Authors: Ijuomah A.O. , Ike D.C. , Obi M.C.
Published: July 2022

This study describes a simple one-pot synthesis of N-pyridin-3-yl-benzenesulfonamide and its antimicrobial activity. The reaction of benzene sulfonyl chloride with 3-aminopyridine in the presence of aqueous Na2CO3 and HCl as a scavenger furnished the sulfonamide in 93.3% yield. The structure of the synthesized compound was established using the spectral data obtained from FTIR, 1HNMR and 13CNMR). All spectrometric spectrum bands and peaks obtained were sulfonamide-related. The antibacterial test carried out against Gram-positive bacterium (Staphylococcus aureus) and Gram-negative bacteria (Salmonella typhi and Eschericha coli) tested upon at concentrations 150, 100, 50 and 25 mg/ml revealed that the synthesized N-pyridin-3yl-benzenesulfonamide possesses great antimicrobial activity.
Work between Creation and Re-creation
Authors: STEENSMA DOUWE J.
Published: July 2022

This Article Develops Biblical Notions About Work. People Expect Happi- Ness From Working Hard, And Many Achieve That Goal. However, Some Suffer From Stress-related Complaints And Burnout, And Some Occupa- Tions Also Contribute To The Global Ecological Crisis. However, Many People Also Seek To Regain The Meaningfulness Of Work For Their Fellow Human Beings, Society, And The Environment. Theology Can Speak To The Issue Of Work With Its Two Faces. Work Should Be Seen From The Perspec- Tives Of Creation And Re-creation. It Has Not Only Instrumental Value (regarding Livelihood, Character Formation, Exercise In Moderation, And Care For Creation) But Also Inherent Value. This Notion Is Essential For Regaining Joy In Work. KEYWORDS: Work, Labor, Creation, Re-creation, Vita Activa, Creation Mandate, Vocation
In Memoriam, In Whan Kim (1946–2021)
Authors: Lillback Peter A.
Published: July 2022

It Is With Sadness, Yet In The Hope Of Christ’s Resurrection, That We Announce The Death Of One Of Unio Cum Christo’s Editorial Board Members, Dr. In Whan Kim (1946–2021).We Extend Our Sympathies To His Family, Colleagues, And Friends.
Dr. Kim Served At Chongshin Universi- Ty And Seminary And More Recently As President Of Daeshin University And Seminary, Gyeongsan, South Korea. Ordained In The Presbyterian Church In America In 1981, He Served As A Pastor In The United States And Korea. A Trained Old Testament Scholar, He Wrote Many Books And Articles In Korean And English. He Completed His PhD Dissertation, “An Analysis And Evaluation Of The Tithe Practice Of The Korean Protestant Church From The Perspective Of The Biblical Tithe Law,” At The University Of Wales In 2000. A Philanthropist, He Was Awarded The Recognition Of Education By The President Of The Republic Of Korea (2011). He Was Active In Several International Societies, In Particular The World Reformed Fellowship. (For More Information, See “Dr. In Whan Kim (In Memoriam),” Https://wrf.global/about/board-of-directors.) KEYWORDS:
Rendimiento Empresarial, Resilencia e Innovación en PYMES
Authors: Demuner-Flores María del Rosario , Saavedra-García María Luisa , Cortés Castillo María del Rosario
Published: July 2022

El objetivo fue evaluar las relaciones resiliencia - innovación – rendimiento empresarial, y estudiar el efecto mediador de la innovación. Se desarrolló el método de estructuras estructurales con mínimos cuadrados parciales (PLS-SEM), para probar las hipótesis. Los datos fueron recolectados de 93 restaurantes mexicanos (PYME). Los resultados validan que la resiliencia y la innovación ejercen influencia positiva en el rendimiento empresarial, la resiliencia influye en la innovación y se comprobó la mediación de la innovación. El modelo explicó la existencia de prácticas de innovación que intensificaron el efecto de la resiliencia en el rendimiento. La originalidad consiste en mostrar la resiliencia como la gran oportunidad de las PYME para responder proactivamente durante y después de la crisis. Los principales demostraron la importancia de involucrar actividades de alto nivel en las PYME para mejorar sus posibilidades de éxito. Limitaciones: Tamaño muestral minimizado al contrastar con estudios similares y encontrar correspondencia; utilizar una técnica estadística exploratoria, que abrió la posibilidad de utilizar próximamente estructuras estructurales (covarianzas) incluyendo el aprendizaje como otra capacidad dinámica mediadora.
Modelo Predictivo de Predisposición y Compromiso Organizacional.
Authors: Nava-Soto Mariana Ivonne , García-Uribe Emmanuel Francisco , Patricia Ramos-Rubio Patricia
Published: July 2022

El objetivo del presente trabajo es validar un modelo de predisposición y compromiso organizacional a partir de la teoría de Cohen (2007). El método empleado fue la técnica multivariada de Cuadrados Mínimos Parciales (PLS-SEM) en una muestra de 184 empleados de la industria maquiladora en Cd. Juárez. Como resultado se encontró evidencia de que la predisposición instrumental y normativa tienen un efecto directo, positivo y significativo sobre el compromiso afectivo e instrumental. La relevancia de este hallazgo radica en la aportación del sustento empírico a la teoría de dos dimensiones propuesta por Cohen (2007) y su originalidad reside en la inclusión de las teorías del comportamiento planeado (TCP) y de acción razonada (TAR) para estudiar la predisposición para el compromiso. Como limitaciones,
Análisis Discriminante de las Capacidades de Absorción y la Competitividad
Authors: Carrazco-Escalante José Crisóforo , Rojas-Rodríguez Isaac Shamir , Rossetti-López Sergio Ramón
Published: July 2022

El objetivo del trabajo es aplicar el análisis discriminante para evaluar las Capacidades de Absorción del Conocimiento (CapAb) y su impacto en la competitividad de las granjas camaronícolas en Ahome, Sinaloa. Como método se aplicaron herramientas propias del análisis discriminante a los datos obtenidos de la aplicación de una encuesta aplicada a 58 empresas dedicadas al cultivo de camarón a través de una perspectiva cualitativa, descriptiva y cuantitativa. Como resultados se obtuvo evidencia empírica con un fuerte respaldo teórico que las CapAb ejercen influencia en la competitividad empresarial, teniendo como variables de mayor influencia en la discriminación de grupos de competitividad media-baja y competitividad alta, a la Capacidad de; Absorción, Asimilación, Transformación, Explotación y el tamaño de la empresa. Su originalidad radica en aportar hallazgos referentes a la importancia de ciertas CapAb para un sector específico, la cual a su vez es una de las limitaciones del trabajo.
Pasión Empresarial, Capacidad de Adaptación y Orientación Estratégica
Authors: Montiel-Campos Héctor
Published: July 2022

El objetivo de este estudio es explorar la relación entre la pasión empresarial por desarrollar y la orientación estratégica basada en oportunidades considerando la alerta empresarial como variable mediadora y la capacidad de adaptación como variable moderadora. Se recopilaron datos de 137 pequeñas empresas de la región sur de México entre agosto y noviembre de 2019, los cuales fueron analizados con un método de mediación moderada. Los resultados muestran que la alerta empresarial media parcialmente la relación entre la pasión empresarial y la orientación estratégica. Los hallazgos también indican que los efectos indirectos de la pasión empresarial sobre la orientación estratégica a través de la alerta empresarial son moderados por la capacidad de adaptación. La originalidad de este estudio contribuye a la literatura sobre emprendimiento y estrategia al demostrar que la relación entre la pasión empresarial y la orientación estratégica puede entenderse mejor cuando se incluyen variables mediadoras y moderadoras adecuadas teniendo en consideración las limitaciones que esto conlleva.
Gestión financiera y desempeño en MiPyMes Colombianas y Mexicanas
Authors: Mayett-Moreno Yesica¿ , Zuluaga-Muñoz Guillermo , Guerrero-cabarcas mauricio javier
Published: July 2022

La escasa utilización de indicadores clave de desempeño financiero en Mipymes latinoamericanas reduce su competitividad. Objetivo: dimensionar el grado de utilización de criterios financieros y no financieros. Método: se encuestaron por conveniencia 74 dueños de Mipymes colombianas y mexicanas (2018, 2020); la prueba no paramétrica de la mediana contrastó diferencias. Resultados y hallazgos: Para emprender los mexicanos realizan pocos estudios técnicos, financieros o de mercado e invierten mayor tiempo en tramitar licencias sanitarias y seguro social. El conocimiento sobre tasas de interés y rendimiento en acciones fueron similares en ambos países. En financiación, recurren a fondos internos más que a bancos por las altas tasas de interés. La aprobación de crédito fue menor en Colombia, considerando el acceso a financiación un obstáculo. Originalidad: Primer estudio sobre la escasa utilización de indicadores financieros clave en Mipymes urbanas Bogotá-Puebla. e Limitaciones: estudio exploratorio, tamaño de la muestra reducido y muestreo no aleatorio.
Gestión financiera y desempeño en MiPyMes Colombianas y Mexicanas
Authors: Mayett-Moreno Yesica , Zuluaga-Muñoz Guillermo , guerrero-cabarcas mauricio javier
Published: July 2022

La escasa utilización de indicadores clave de desempeño financiero en Mipymes latinoamericanas reduce su competitividad. Objetivo: dimensionar el grado de utilización de criterios financieros y no financieros. Método: se encuestaron por conveniencia 74 dueños de Mipymes colombianas y mexicanas (2018, 2020); la prueba no paramétrica de la mediana contrastó diferencias. Resultados y hallazgos: Para emprender los mexicanos realizan pocos estudios técnicos, financieros o de mercado e invierten mayor tiempo en tramitar licencias sanitarias y seguro social. El conocimiento sobre tasas de interés y rendimiento en acciones fueron similares en ambos países. En financiación, recurren a fondos internos más que a bancos por las altas tasas de interés. La aprobación de crédito fue menor en Colombia, considerando el acceso a financiación un obstáculo. Originalidad: Primer estudio sobre la escasa utilización de indicadores financieros clave en Mipymes urbanas Bogotá-Puebla. e Limitaciones: estudio exploratorio, tamaño de la muestra reducido y muestreo no aleatorio.
Pengaruh Penambahan Tepung Biji Nangka (Artocarpus heterophyllus Lamk.) sebagai Substitusi Tepung Tapioka terhadap Mutu Bakso Daging Ayam
Authors: Hasnita Hasnita , Husain Halimah , Jusniar Jusniar
Published: July 2022

ABSTRAKPenelitian ini bertujuan untuk mengetahui pengaruh penambahan tepung biji nangka sebagai substitusi tepung tapioka terhadap mutu bakso daging ayam. Jenis penelitian ini merupakan penelitian eksperimen meliputi preparasi sampel, perendaman, pengeringan, pengayakan, uji mutu tepung, pembuatan bakso daging ayam dan uji mutu bakso daging ayam. Mutu bakso daging ayam yang dimaksud pada penelitian ini dilihat dari aspek kimia meliputi kadar air, kadar abu, kadar ptotein, kadar lemak dan uji organoleptik meliputi warna, aroma, rasa dan tekstur. Pembuatan bakso daging ayam menggunakan perbandingan 1 : 2 (tepung : daging ayam) dimana tepung yang digunakan bervariasi yaitu a (100% tepung tapioka : 100 gram daging ayam), b (50% tepung tapioka : 50% tepung biji nangka : 100 gram daging ayam) dan c (100% tepung biji nangka : 100 gram daging ayam). Hasil analisis aspek kimia bakso daging ayam tepung biji nangka sebagai substitusi tepung tapioka yaitu kadar air 64,69%, kadar abu 1,24%, kadar protein 8,34%, kadar lemak 0,39% dan uji organoleptiknya yaitu warna 3,00, aroma 2,87, rasa 2,81 dan tekstur 3,12.Kata Kunci : Artocarpus heterophyllus Lamk, Tepung Biji Nangka, Bakso Daging Ayam, Uji Organoleptik ABSTRACTThis research aimed to determine the effect of jackfruit seed flour addition as tapioka flour substituted to the quality of chicken meatballs. This research was an experimental research consisted of several stage include sample preparation, maseration, drying, sieving, flour quality test, chicken meatballs production and chicken meatballs quality test. Quality of chicken meatballs referred to the chemical aspect include water content, ash content, ptotein content, fat content and organoleptic test include color, aroma, flavor and texture. Chicken meatballs was produced using a ratio of 1: 2 (flour: chicken), where the flour used vary namely a (100% of tapioca flour : 100 grams of chicken meat), b (50% tapioca flour : 50% jackfruit seeds flour : 100 grams of chicken meat) and c (100% jackfruit seed flour : 100 grams chicken meat). The chemical aspect analysis result of chicken meatball using jackfruit seed flour as tapioka flour substituted showed that the water content of 64.69%, ash content of 1.24%, protein content of 8.34%, fat content of 0.39% and the organoleptic test is 3,00 of color, 2,87 of aroma, 2,81 of flavor and 3,12 of texture.Keywords: Artocarpus heterophyllus Lamk, Jackfruit Seed Flour, Chicken Meatballs, Organoleptic Test.
Pengaruh pH terhadap Massa Kristal Tunggal Kalsium Tartrat Tetrahidrat (CaTT) dari Limbah Cangkang Telur Ayam dengan Metode Gel Metasilikat
Authors: Ahmad Angriyani , Putri Suriati Eka , Syahrir Muhammad
Published: July 2022

ABSTRAKPenelitian ini bertujuan untuk menentukan pengaruh pH awal gel terhadap massa kristal tunggal kalsium tartrat tetrahidrat dari cangkang telur ayam dengan metode gel metasilikat. Serbuk cangkang telur ayam yang telah dikalsinasi memiliki kandungan CaO sebesar 99,53%. Serbuk CaO dari cangkang telur ayam yang direaksikan dengan asam klorida (HCl) 1,5 M menghasilkan kalsium klorida (CaCl2). Kalsium klorida selanjutnya digunakan sebagai larutan supernatan dalam sintesis kristal tunggal kalsium tartrat tetrahidrat (CaTT). Natrium silikat (Na2SiO3) yang direaksikan dengan asam tartrat (C4H6O6) membentuk gel metasilikat dengan variasi pH awal gel (pH 3,50; 4,00; 4,50; 5,00 dan 5,50). Supernatan CaCl2 berdifusi ke dalam gel dan membentuk kristal CaTT berwarna kuning bening yang tidak larut dalam akuades. pH awal gel berpengaruh pada massa kristal CaTT dimana pada pH rendah 3,50 dan 4,00 menghasilkan kristal dengan massa rata-rata 0,1722 g dan 0,2191 g, pada pH 4,50 sebesar 0,3003 g dan pada pH 5,00 dan 5,50 massa kristal yang dihasilkan berturut turut yaitu 0,2289 g dan 0,2116 g. Karakterisasi kristal hasil sintesis menggunakan XRD membuktikan bahwa kristal hasil sintesis adalah kristal CaTT tunggal dengan sistem kristal ortorombik.Kata kunci: Cangkang telur ayam, gel metasilikat, kalsium tartrat tetrahidrat ABSTRACTThis study aims to determine the effect of the initial pH of the gel on the single crystal mass of calcium tartrate tetrahydrate from chicken egg shell using the metasilicate gel method. The calcined chicken egg shell powder has a CaO content of 99.53%. CaO powder from chicken egg shells reacted with 1.5 M hydrochloric acid (HCl) produced calcium chloride (CaCl2). Calcium chloride is then used as a supernatant solution in the synthesis of single crystals of calcium tartrate tetrahydrate (CaTT). Sodium silicate (Na2SiO3) reacted with tartaric acid (C4H6O6) formed a metasilicate gel with a variation of the initial pH of the gel (pH 3.50; 4.00; 4.50; 5.00 and 5.50). The CaCl2 supernatant diffuses into the gel and forms clear yellow CaTT crystals which are insoluble in distilled water. The initial pH of the gel affected the crystal mass of CaTT where at low pH 3,50 and 4,00 produced crystals with an average mass of  0,1722 g and 0,2191 g, at pH 4,50 of 0,3003 g and at pH 5,00 and  5,50 crystal masses produced were 0,2289 g and 0,2116 g, respectively. Characterization of crystals synthesized using XRD proves that the synthesized crystals are single CaTT crystals with orthorhombic crystal systems.Keywords: Chicken egg shell, metasilicate gel, calcium tartrate tetrahydrate
Isolasi dan Identifikasi Senyawa Metabolit Sekunder Ekstrak Kloroform Daun Sawo Manila (Manilkara zapota)
Authors: Perdana Rini , Salempa Pince , Side Sumiati
Published: July 2022

ABSTRAKPenelitian ini adalah penelitian eksplorasi yang bertujuan untuk mengisolasi dan identifikasi senyawa metabolit sekunder yang terdapat dalam ekstrak kloroform daun Manilkara zapota. yang berasal dari Kecamatan Tempe Kabupaten Wajo Sulawesi Selatan. Isolasi dilakukan dalam beberapa tahap yaitu maserasi, partisi dengan kloroform, fraksinasi, uji kemurnian dan identifikasi. Hasil penelitian diperoleh isolat murni berupa serbuk berwarna putih dengan titik leleh 140-142oC. Hasil uji dengan pereaksi Liebermann-Buchard mengalami perubahan warna dari bening menjadi hijau menunjukkan positif steroid. Isolat diidentifikasi dengan menganalisis spektrum infra merah yang menunjukkan bilangan gelombang (cm-1) yakni: 3442,94 (-OH terikat); 2947,23 dan 2873,94 (-CH alifatik); 1732,08 (C=O karboksilat); 1249,87 dan 1026,13 (C-O alkohol). Berdasarkan hasil analisis dan penelusuran literature adalah senyawa golongan steroid.Kata kunci : Isolasi, M. zapota, Steroid. ABSTRACTThis is an exploratory research that aims to isolate and identify secondary metabolite compound contained in cloroform Extract of Manilkara zapota leaves from Tempe, Wajo, South Sulawesi. The isolation was done through several stages: maceration, partition with cloroform, fractionation, purity testing, and identification. The extract was found to contain white powder of pure isolate with a melting point of 140-142oC. The test result using Liebermann-Buchard reagent exhibited a shift of color from transparent into green, therefore it can be categorized as a positive steroid. The isolate was identified by analyzing the infra red spectrum which showed wave numbers (cm-1) of: 3442.94 (-OH bond); 2947.23 and 2873.94 (-CH aliphatic); 1732.08 (C=O carboxylate); 1249.87 and 1026.13 (C-O alcohol). Based on the analysis, literature search the isolate is considered as steroid compound.Keywords : Isolation, M. zapota, Steroid.
Isolasi dan Identifikasi Senyawa Steroid Ekstrak N-Heksana Daun Sawo Manila (Manilkara zapota)
Authors: Dilla Ida Ratna , Danial Muhammad , Herawati Netti
Published: July 2022

ABSTRAKPenelitian ini adalah penelitian eksplorasi yang bertujuan untuk mengisolasi senyawa metabolitsekunder yang terdapat dalam ekstrak n-heksana daun M Zapota yang berasal dari Kec.Tempe Kab. Wajo. Isolasi dilakukan dalam beberapa tahap yaitu maserasi, partisi dengan n-heksana, fraksinasi,uji kemurnian dan identifikasi. Hasil penelitian diperoleh isolate murni berupa Kristal jarum berwarna putih bening. Hasil uji dengan pereaksi Liebermann-Buchard membentuk cincin biru menunjukkan positif steroid. Isolat diidentifikasi dengan menganalisis spektrum inframerah yang menunjukkan bilangan gelombang (cm-1) yakni: 1055,25 (C-O);1462,04 dan 1375,25 (CH2 dan CH3),1651,07 (C=C); 2965,87 (C-H);3437,15 (OH alkohol) Berdasarkan hasil analisis dan penelusuran literature, senyawa metabolit sekunder yang didapatkan  adalah senyawa golongan steroid.Kata kunci : Isolasi, M. zapota, Steroid. ABSTRACTThis study is exploratory research that aim to isolate the secondary  metabolite compound contained in the n-hexane extract of leaves of Manilkara Zapota from Kec Tempe.Kab. Wajo. Isolation is done in several stages, maceration, partitioning with n-hexane, fractionation, purity testing and identification. The test result with the Liebermann-Buchard reagent to form a blue ring indicated a positive steroid. Isolate was identified by analyzing the infrared spectrum which showed the wave number (cm-1) are: : 1055,25 (C-O);1462,04 and 1375,25 (CH2 and CH3),1651,07 (C=C); 2965,87 (C-H);3437,15 (OH alkohol. Based on the analysis and literature searchthat isolateis steroid compound.Keywords : Isolation, M. zapota, Steroid.
Studi Kandungan Senyawa Metabolit Sekunder beberapa Ekstrak Tai Anging (Usnea sp.) dan Uji Bioaktivitasnya terhadap (Candida albicans)
Authors: Utami Nurul , Auliah Army , Dini Iwan
Published: July 2022

ABSTRAKPenelitian ini merupakan penelitian eksperimen yang bertujuan mengetahui kandungan seyawa metabolit sekunder yang terdapat pada ekstrak kloroform, etil asetat, dan methanol dari tumbuhan tai anging (Usnea sp.) dan uji bio aktivitasnya sebagai anti jamur Candida albicans yang merupakan jamur penyebab penyakit Candidiasis. Metode penelitian yang dilakukan meliputi maserasi, uji golongan, KLT, dan uji bioaktivitas antijamur. Hasil uji golongan ekstrak kloroform mengindikasikan mengandung senyawa golongan flavanoid dan ekstrak etil asetat mengandung senyawa golongan alkaloid dan flavanoid serta ekstrak methanol mengandung senyawa golongan steroid, alkaloid dan flavanoid. Berdasarkan hasil uji bioaktivitas antijamur, ekstrak kloroform memiliki potensi yang paling besar sebagai antijamur, dengan rata-rata diameter hambat 15,284 mm terhadap Candida albicans pada konsentrasi 5% (m/v).Kata kunci :Tai anging, Usnea sp., Candida albicans, Candidiasis ABSTRACTThis study is an experiment research that aimed to know the content of secondary metabolites compound in extract of chloroform, ethyl acetate and methanol from  taianging plants (Usnea sp.) And test the of bioactivity as antifungal Candida albicans is thats caused candidiasis. The method of include maceration, phytochemical test, TLC and antifungal bioactivity test. The result indicate compound containing chloroform extract group and the ethyl acetate extract flavanoid compounds containing alkaloids and flavonoids, and the methanol extract contains compounds steroids, alkaloids and flavonoids. The result indicated flavonoid compound of  extract, alkaloid and flavonoid compound of ethyl acetate extract, and steroid, alkaloid  and  flavonoid compound of methanol extract. Based on antifungal bioactivity, test chloroform extract was  greatest  as an antifungal, with average diameter of 15,284 mm inhibition against Candida albicans at a concentration of 5% (m/v).Keywords: Tai anging, Usnea sp., Candida albicans, Candidiasis
Changes in the activity of metalloprotease ADAMTS13 antigen von Willebrand factor in patients with acute coronary syndrome
Authors: Koloskov A. V. , Mangushlo A. A. , Beliaeva E. L. , Philippova O. I. , Chernova E. V. , Shenderov S. V. , Marchenko V. N.
Published: July 2022

Introduction. Currently, considerable attention is being given to the study of the interaction of the von Willebrand factor (vWF) and its specific regulator of metalloprotease ADAMTS13 in various clinical conditions accompanied by the development of thrombosis.

Aim — to assess the change in the activity of ADAMTS13 metalloprotease and vWF factor antigen in patients with acute coronary syndrome during the first five days after the onset of an anginal attack.

Patients and methods: The study included 90 patients aged 42 to 86 years (Me — 61.5 y.o.) hospitalized with a diagnosis of acute coronary syndrome. Of these, 69 were men (Me — 59 y.o.) and 21 women (Me — 63 y.o.). All patients were tested for ADAMTS13 activity, ADAMTS13 antigen, and vWF antigen. Blood samples for the study were obtained upon admission to the hospital (arterial and venous blood), as well as 24, 72 and 120 hours after hospitalization (venous blood).

Results. It was found that at all points of the study, in patients without coronary artery thrombosis, the average value of the ADAMTS13 activity indicator was significantly higher compared to the group of patients with coronary artery thrombosis. At the same time, there were no statistically significant differences in the average values of the ADAMTS13 antigen between the compared groups of patients. The mean value of vWF antigen in patients with coronary artery thrombosis was significantly higher compared to that of patients without coronary artery thrombosis.

Conclusion. An increase in ADAMTS13 activity was noted more often in patients with acute coronary syndrome without coronary artery thrombosis than in patients with coronary artery thrombosis, which may indicate the antithrombotic effect of ADAMTS13 metalloprotease. No differences were found in ADAMTS13 antigen levels when comparing the study groups of patients, which indicates a greater significance for the anticoagulant activity of the functional characteristics of ADAMTS13. Significantly higher levels of the vWF antigen in patients with coronary artery thrombosis were due to the response to ischemic myocardial injury and stress but were not the primary cause of the thrombotic event.
Thrombosis in patients with hereditary fibrinogen deficiency
Authors: Yakovleva E. V. , Salomashkina V. V. , Surin V. L. , Selivanova D. S. , Lavrova P. S. , Gorgidze L. A. , Soboleva N. P. , Zozulya N. I.
Published: July 2022

Introduction. In most cases, in patients with hereditary fibrinogen deficiency, clinical manifestations are represented by bleeding of varying intensity and localization. However, the clinical picture of hereditary fibrinogen deficiency can also be represented by thrombosis.

Aim — to characterize the detected mutations in fibrinogen genes and to analyze prothrombotic factors in patients with hereditary hypofibrinogenemia and thrombosis.

Materials and methods. Forty-nine patients with hereditary hypofibrinogenemia were observed, of which 46 patients had no history of thrombosis and 3 patients had a confirmed history of thrombosis. These 3 patients made up the study group.

Results. Heterozygous mutations were found in all 3 patients in the fibrinogen gamma chain gene (FGG), one of them had a previously undescribed deletion g.2653_2684+211del, p.(Asp167Glufs*2), which removes 32 terminal nucleotides of the fifth exon of the FGG gene and leads to the formation of a stop codon in place of amino acid 168. In two other patients, there were missense mutations c.1140T>A, p.(Cys365Ser) and c.1114A>T, p.(Asp356Val), which can determine the thrombogenic properties of the altered protein structure of fibrinogen. Other prothrombotic factors were also identified: genetic polymorphisms of low thrombotic risk, surgery, taking combined oral contraceptives.

Conclusion. Hereditary fibrinogen deficiency does not play a protective role in relation to the development of thrombosis and may cause the development of thrombosis, which is associated with its multifunctional role in the hemostasis system. The pathogenesis of thrombosis in patients with hereditary hypofibrinogenemia is multifactorial and may be associated with the characteristics of the main protein defect and the coexistence of hereditary and acquired thrombotic risk factors (surgical interventions, taking combined oral contraceptives, etc.).
Measures of social support for blood donors during the formation of the donor movement in the USSR
Authors: Serebryany R. S. , Kamelskikh D. V.
Published: July 2022

Introduction. The period of formation of the donor community in the USSR fell on the 30–40s of the twentieth century. The first measures to organize the donor community were of a spontaneous nature. However, beginning in the 1930’s, with the support of the state and public organizations in the USSR, on the eve of the war, a mass donor community arose based on the ideology of the time and system of motivations.

Aim — to reconstruct the measures of social support for blood donors, which contributed to the formation of the donor community in the USSR and to identify the role of the state in organizing the donor community in the USSR.

Main findings. To conduct the study, a set of methods was used, including the study and generalization of experience based on archival sources, monographic description, and narrative analysis. A number of archival materials are introduced into scientific circulation for the first time. Decrees of the Council of People’s Commissars of the RSFSR, issued in the 30–40s of the 20th century, which formed the basis of the legal framework for organizing social support for donors, are given. This article is devoted to the emergence and development of the donor community in the USSR. A number of measures of social support for blood donors are described, which are characteristic of various stages in the development of the donor community (“attracting and retaining” donors in the 1930s, “survival” of donors at the beginning of the Great Patriotic War, and their “encouragement” at the final stage of the Great Patriotic War). Measures of social support for blood donors, which arose in the pre-war period, proved their effectiveness (attracting about 5.5 million people into the ranks of donors, from whom 1.7 million liters of blood were harvested) during the Great Patriotic War, and with some changes, maintain their relevance today.
Thermophysical properties of molten Ga2O3 by using the electrostatic levitation furnace in the International Space Station
Authors: Yoshida Kenji , Kumagai Hirohiko , Yamane Takayoshi , Hayashi Atsushi , Koyama Chihiro , Oda Hirohisa , Ito Tsuyoshi , Ishikawa Takehiko
Published: July 2022

We measured the thermophysical properties of molten gallium oxide (Ga2O3) in a contamination-free and microgravity environment by using the electrostatic levitation furnace in the International Space Station. The density of molten Ga2O3 was obtained over a wide temperature range of 2001–2174 K including the undercooled state and found to be expressed as 5004.8–0.4478(T − T
m) (kg m−3), where T
m, the melting point, is 2066 K. Measurements of its viscosity and surface tension were also performed by using the drop oscillation method and these values were found to be 337.0 (10−3 N m−1) and 13.6 (10−3 Pa·s) at 2228 K, respectively.
Application of NLP and Machine Learning for Mental Health Improvement
Authors:   M. Tech Student, Department of Data Science and Business Systems, SRM Institute of Science and Technology, Chennai (Tamil Nadu), India., Borah Trinayan , Kumar S. Ganesh ,   Professor, Department of Data Science and Business Systems, SRM Institute of Science and Technology, Chennai (Tamil Nadu), India.
Published: July 2022

Humans' most powerful tool is their mental wellness. Individuals' well-being can be impacted by poor mental health. This paper focuses on a smart technical solution to the problem of mental health issues detection related to the stress, sadness, depression, anxiety etc. which if not handled efficiently may further lead to a severe problem. The paper deals with the designing of an automated smart system using social media posts, that will help mental health experts to successfully identify and understand about the mental health condition of social media users. That can be done based on text analysis of rich social media resources such as Reddit, Twitter posts. The implementation of the system is done using Natural Language Processing (NLP) methods, machine learning and deep learning algorithms. The models are trained using a prepared dataset of social media postings. With this automated system the mental health experts can able to detect the stress or some other emotions of social media uses in a very earlier as well as faster way. The proposed system can predict five emotional categories: 'Happy', 'Angry', 'Surprise', 'Sad', 'Fear' based on machine learning (Logistic Regression, Random Forest, SVM), deep learning Long Short-Term Memory (LSTM) and BERT transfer learning algorithms. All the applied algorithms are evaluated using confusion matrix, the highest accuracy and f1 score achieved is more than 90%, which is better than the existing human emotion detection systems.
Measurement and Analysis of Vector Network Analyzer
Authors:   Department of Electronics & Communication Engineering, G. Pulla Reddy Engineering College (A) Kurnool, (Andhra Pradesh), India., Thilagam J.Salai Thillai , Vittal Dr. M.V.R. ,   Department of Electronics & Communication Engineering, G. Pulla Reddy Engineering College (A) Kurnool, (Andhra Pradesh), India., Khan Dr. G.Amjad ,   Department of Electronics & Communication Engineering, G. Pulla Reddy Engineering College (A) Kurnool, (Andhra Pradesh), India., Reddy B.Siva ,   Department of Electronics & Communication Engineering, G. Pulla Reddy Engineering College (A) Kurnool, (Andhra Pradesh), India.
Published: July 2022

One of the main instrument used in the microwave communication laboratory is analyzer. Particularly, network analyzer, which is used for testing the RF components. Here in this paper the vector network analyzer design study and measurement analysis is discussed. The introduction to Vector Network Analyzer (VNA), working, types, blocks, function, measurements and specifications are presented as revisiting the technologies. As a DUT, a fractal antenna is connected to VNA and its results are presented.
User Interface and AI Navigation System for Autonomous Vehicle
Authors:   M.Tech Student, Department of Mechanical Engineering, MIT ADT University, Pune (Maharashtra), India., Satav Aalhad , Patel Nishigandha ,   Assistant Professor, Department of Mechanical Engineering, MIT ADT University, Pune (Maharashtra), India.
Published: July 2022

The issue of vehicle accidents due to human error and behavior (rash driving, drink and drive, etc.) is on rising resulting into fatality and economical loss. In order to overcome these issues, the autonomous vehicle is being explored as a probable solution. Driver will be replaced by AI based autonomous system; The main objective is to convert the manual operated EV into autonomous vehicle. The project work is divided into three main parts i.e., Control System for Vehicle Control, AI (Artificial Intelligence) and UI (User Interface). The main objective of User Interface is to give information regarding vehicles health i.e. battery remaining, charging time, distance to be covered, etc. AI will be use as decision making system or we can say brain of the autonomous vehicle. System Control or Vehicle Control System is to control the vehicle’s steering, acceleration and braking system with the help of PID controller while the vehicle is being operated in autonomous mode. The main purpose is to make an autonomous EV for the passengers to go to their selected destination with a single click by selecting destination on display (UI). So the vehicle control is responsible for the vehicle’s steering i.e., at what desired angle the vehicle need to turn, during acceleration the factors that are considered are; at what speed the vehicle needs to move in an straight path or during a turn and the braking system is operated with the help of LIDAR where if it detects an object at what distance it needs to apply the brakes and when to release the brakes. All the factors and conditions required in developing the autonomous vehicle will be considered, as use cases to improve the accuracy of autonomous vehicle, resulting into achieving desired objective of safe travel.
Intelligent Deployment Strategy for Heterogeneous Nodes to Increase the Network Lifetime of Wireless Sensor Networks
Authors:   Ph.D. (Pursing), Sriram Chandra Bhanja Deo University, Baripada (Odisha), India., Dora Sidhartha Sankar , Swain Dr. P.K. ,   Assistant Professor, Department of Computer Application, North Orissa University, India.
Published: July 2022

The applications of wireless sensor networks are increased day by day for different applications. Heterogeneous wireless sensor networks offer limitless possibilities because to their expandable capabilities, such as diverse computing power and sensing range, but they also represent significant issues due to the scarcity of energy, which is typically non-renewable. The node deployment, coverage area, connectivity, power depletion and network life time are major issues in wireless sensor networks. We have deployed heterogeneous sensor nodes on the basis of energy to design a heterogeneous network model and applied intelligent node deployment techniques by using metaheuristic algorithms such as genetic algorithm (GA) and particle swarm optimization (PSO) algorithm to minimize the power depletion of sensor nodes for enhancing network life time using multi-hop transmission in this paper. The benefits of heterogeneity have been revealed by our experimental findings.
NUTUKIMO HIPOVENTILIACIJOS SINDROMAS: SAMPRATA, EPIDEMIOLOGIJA, KLINIKINIS PASIREIŠKIMAS IR DIAGNOSTIKA
Authors: Ulvidaitė Šarūnė
Published: July 2022

Nutukimo hipoventiliacijos sindromas yra kvėpavimo sistemos sutrikimas, kuriam būdinga požymių triada: nu­tukimas (kūno masės indeksas ≥ 30 kg/m2), kvėpavimo sutrikimas miegant bei hiperkapnija ir hipoksemija, ku­rios nustatomos dieną arterinio kraujo dujų tyrime. Nu­tukimo hipoventiliacijos sindromo paplitimas pasaulyje svyruoja nuo 0,15 iki 0,3 proc. ir, laikui bėgant, jo papli­timo tendencija gali didėti dėl vis didėjančio nutukimo paplitimo visame pasaulyje. Nutukimo hipoventiliacijos sindromui būdingi įvairūs simptomai: knarkimas, apnėja miego metu, prasta miego kokybė, rytinis galvos skaus­mas, mieguistumas dieną. Dažniausiai diagnozuojamas tik penkiasdešimties ar šešiasdešimties metų pacientams. Dėl to vienas iš svarbiausių NHS valdymo elementų yra ankstyvoji diagnostika. Nutukimo hipoventiliacijos sin­dromas diagnozuojamas remiantis šiam sindromui bū­dingais diagnostikos kriterijais, o auksiniu diagnostikos standartu laikomas arterinio kraujo dujų tyrimas. Šia literatūros apžvalga siekiama pateikti nutukimo hipoven­tiliacijos sampratą, epidemiologiją, klinikinį sindromo pasireiškimą bei pagrindinius diagnostikos metodus. Tikslas – atlikti mokslinių šaltinių, analizuojančių nu­tukimo hiperventiliacijos sindromo sampratą, epidemio­logiją ir pasireiškimą sisteminę analizę, bei apibendrinti pagrindinius diagnostikos metodus.
KASOS VĖŽIO GYDYMO STRATEGIJOS
Authors: Mažeikaitė Morta
Published: July 2022

Europos šalyse ir Jungtinėse Amerikos Valstijose mirš­tamumas nuo kasos vėžio užima ketvirtą vietą tarp visų onkologinių ligų. Sergančiųjų kasos vėžiu 5 metų išgy­venamumas vidutiniškai siekia apie 5-10 procentų. Dau­geliu atvejų ši liga aptinkama jau vėlyvose stadijose, tad chirurginis gydymas tėra galimas vos 15-20 proc. paci­entų. Nustačius rezektabilų kasos vėžį, rekomenduojama gydymą pradėti skiriant neoadjuvantinę chemoterapiją, atlikti naviko rezekciją, po operacinio gydymo taikyti adjuvantinę chemoterapiją. Potencialiai rezektabilius navikus siūloma gydyti chemoterapijos preparatais. Nau­jausi šaltiniai nurodo, jog gydymas chemoradioterapija pasižymi teigiamu klinikiniu atsaku, ypač tais atvejais, jei navikas kontaktuoja su didžiosiomis arterijomis. Lo­kaliai išplitusio kasos vėžio gydymo planas sudaromas skiriant chemoterapijos kursą, po kurio, įvertinus klini­kinį atsaką, galima papildomai skirti chemoradioterapinį gydymą. Ligos stadijai pažengus, išsivysčius metastatinei ligai, priklausomai nuo pacientų būklės, jiems taikytinas paliatyvusis gydymas arba įvairaus agresyvumo chemo­preparatai.
Peningkatan Pemahaman Konsep Siswa Kelas V dengan Pemanfaatan Media Pembelajaran Geogebra
Authors: Hakim Luqmanul , Markhamah Markhamah , Sutama Sutama
Published: July 2022

The purpose of this research is to create a learning media for the concept of geogebra to improve students' mathematical understanding of the material of spatial structure. The things tested in this study were validity, practicality, and effectiveness. This research method is R&D with a 4-D model, namely defining, designing, developing and distributing. However, in this study only up to the development stage. Based on the research that has been done, the result is that the average score of media experts is 3.6, material experts are 3.6, which means the results are very good. Furthermore, the practicality score obtained from the teacher's response questionnaire is 89,93% and the student's is 78,67%. Furthermore, the results of the effectiveness of learning media get 90% of students who get complete learning using geogebra learning media.
Konsep Akhlak Bagi Peserta Didik dalam Pendidikan Agama Islam Menurut Ibnu Al-Qayyim Al-Jauziyyah
Authors: Fadilla Ananda Octavianie , Rukajat Ajat , Ramdhani Khalid
Published: July 2022

Various phenomena related to the lack of morals and morals among students are currently a decline in the cultural changes brought by the western world to the Muslim community, especially among students, therefore researchers will examine a discussion related to research on the work of bnu Qayyim Al- Jauziyah who is one of the previous scholars who focused on studies and discussions in the field of morality. On the basis of scientific studies. The purpose of this study was to find out the scope of the concept of morality for students in the aspect of the study of Islamic Religious Education which was taken from the author of Ibn Al-Qayyim Al-Jauziyyah by using exemplary and habituation methods so that the formation of good morals for students. The method used in this research is the writer takes the library research method using a qualitative approach taken from various theories and experts in their fields with literary data collection techniques. The results in this study discuss the moral concept of students in the review of Islamic Religious Education and the opinion of the Islamic scholar of moral science Ibn Al-Qayyim Al-Jauziyyah who discusses the good and bad behavior of a person in aspects of his life by getting used to the cultivation of good moral behavior to students which has been carried out since their age is still small by applying the way of example and habituation. The role of both parents, and support from the environmental community and school will determine the results of the formation of good and bad behavior in the morals of students.
Pembinaan Akhlak Siswa melalui Kegiatan Pembinaan Keagamaan di Sekolah Menengah Pertama Negeri 31 Padang
Authors: Illahi Fahira Murni , Satria Rengga
Published: July 2022

The purpose of this study is to find out how moral development is carried out through religious development activities at SMP Negeri 31 Padang and the supporting and inhibiting factors. Religious development activities consist of TPQ, Tahfiz, and Weekly Wirid activities. The research method uses a qualitative method with a descriptive approach. The data in the study were collected through observation, interviews and documentation. The data analysis technique was carried out using the Miles and Huberman model with the flow of data reduction, data presentation, and drawing conclusions. The results showed that moral development through TPQ activities was carried out through habituation, motivation, and advice activities. Meanwhile, moral development through Tahfiz activities is carried out through exemplary activities, invitations, and motivations. As well as moral development through weekly wirid activities, namely in the form of giving stories, reprimands and punishments, and habituation to students. The supporting factors in this religious development activity are facilities and infrastructure, good cooperation between teachers and leaders, and the wishes of students. While the inhibiting factors are the influence of friends, outside activities, and the Covid-19 situation.