bluuebunny/crossref_metadata_2025 huggingface dataset:
Methods of evaluating code generators
Authors:   State University of Information and Communication Technologies, Kyiv, Mykolayenko V. O.
Published: April 2024

In the ever-evolving landscape of software development, code generators have emerged as vital instruments, fostering innovation and efficiency. These automated maestros translate abstract requirements into functional code, significantly reducing development time and bridging gaps across varied programming environments. This article categorizes code generators based on their operational domain, input specificity, and the nature of the output they produce, unraveling a diverse spectrum from foundational scaffolding creators to sophisticated, language-specific assistants. Selecting an apt code generator is pivotal to the success of a project. To assist developers in this critical choice, the article presents an evaluation method that weighs essential factors such as adaptability, efficiency, and ease of integration with existing systems. This systematic approach ensures the selection of a tool that not only meets immediate project needs but also supports future scalability and complexity. The discussion extends beyond functionality to explore the transformative role of code generators. By automating routine coding tasks, they allow developers to focus on more creative aspects of software design, enhancing code quality and fostering a culture of innovation. The generators thus become indispensable allies in the creative process of software development. In essence, the article advocates for an informed selection of code generators, viewing them as cornerstones for modern coding practices. The proposed evaluation method serves as a strategic framework, empowering developers to navigate the myriad of options and align their choice with both current requirements and future aspirations. It is an invitation to embrace the synergy between human creativity and machine precision, crafting code that is both efficient and elegant.
NLR IN URINE: PROGNOSTIC MARKER FOR RECURRENT INFLAMMATORY URINARY TRACT CONDITIONS
Authors:   Tyumen State Medical University, Tyumen, Russia, Berdichevsky Vadim B. , Gutrova Elena I. ,   Tyumen State Medical University, Tyumen, Russia, Sapozhenkova Ekaterina V. ,   Tyumen State Medical University, Tyumen, Russia, Pavlova Irina V. ,   Medical and Sanitary Unit "Neftyanik", Tyumen, Russia, Gonyaev Artem R. ,   Clinical Hospital "Mother and Child", Tyumen, Russia, Boldyrev Alexei L. ,   Regional Clinical Hospital No. 2, Tyumen, Russia, Krasnousova Oksana V. ,   Regional Clinical Hospital No. 1, Tyumen, Russia, Rasulov Farkhod R. ,   Tyumen State Medical University, Tyumen, Russia
Published: April 2024

Аim. The study aims to evaluate the clinical significance of the indicator of nonspecific and specific protection (NLR) in urine as an accessible and objective marker of the type, cause, and possible outcome of recurrent inflammatory diseases of the urinary tract. Materials and Methods. The study included patients with recurrent urinary tract inflammation of various origins. A comparative study of routine laboratory indicators of the ratio of neutrophils and lymphocytes, immune markers of inflammation in urine, and the results of immunohistochemical studies of biopsies of the bladder mucosa was performed. Results. The index of the ratio of cells of nonspecific and specific protection in urine significantly correlates with indicators of phenotyping of T-lymphocytes, the concentration of interleukins in urine, and the composition of cells of the mucous membrane of the bladder with the expression of antigens. Conclusion. The index of the ratio of cells of nonspecific and specific protection (NLR) in urine can be recommended as an additional prognostic marker not only of the type and cause but also of the possible outcome of recurrent inflammatory urological diseases.
PREDICTING NEONATAL PNEUMONIA IN PREGNANT WOMEN WITH NEW CORONAVIRUS INFECTION
Authors:   Novosibirsk City Clinical Perinatal Center, Novosibirsk, Russia, Borovaya Svetlana Yu. , Yakimova Anna V. ,   Novosibirsk State Medical University, Novosibirsk, Russia, Mudrov Viktor A. ,   Chita State Medical Academy, Chita, Russia, Pozdnyakov Ivan M. ,   Novosibirsk State Medical University, Novosibirsk, Russia
Published: April 2024

Introduction. Pregnancy profoundly impacts the immune system, yet the influence of gestational age at COVID-19 contraction and its implications for perinatal outcomes remain uncertain. Aim. This study aimed to evaluate the effects of COVID-19 contracted at various gestational stages on pregnancy and perinatal outcomes. Materials and Methods. Retrospective analysis of medical records from 113 mother-newborn pairs, including COVID-19-positive pregnant women, was conducted at the clinical sites of the Department of Obstetrics and Gynecology of the Novosibirsk State Medical University from 2021 to 2022. The sample was categorized into three study groups based on gestational age at COVID-19 contraction, with a control group of COVID-19-negative pregnant women. Results. Findings revealed a higher incidence of mild COVID-19 in Group 1, while Groups 2 and 3 exhibited a moderate course (p=0.03). Additionally, Groups 2 and 3 demonstrated a higher prevalence of pneumonia (p=0.03) and antibiotic therapy (p=0.02). Complications such as preeclampsia (p=0.002), oligohydramnios (p<0.001), and fetal growth restriction (p=0.02) were more frequent in patients with COVID-19 during pregnancy. Furthermore, fetal distress was more common in study groups 1 and 2 (p=0.002). Neural network analysis allowed for the prediction of pneumonia in newborns with 98.2% accuracy based on factors such as gestational age at COVID-19 contraction, disease severity, presence of oligohydramnios and fetal growth retardation, meconium amniotic fluid, and delivery date. Conclusions. In conclusion, COVID-19 contraction before 34 weeks of gestation often complicates pregnancy, leading to placental insufficiency, preeclampsia, and gestational diabetes mellitus, thereby increasing the risk of early delivery and the birth of low-birth-weight children with reduced adaptive capabilities. The development of pneumonia in these newborns exacerbates their condition, often resulting in perinatal losses. Utilizing a neural network for pneumonia prediction may potentially mitigate perinatal losses.
Combining Ontology and Large Language Models to Identify Recurring Machine Failures in Free-Text Fields
Authors: Bengtsson Marcus , D’Cruze Ricky Stanley , Ahmed Mobyen Uddin , Sakao Tomohiko , Funk Peter , Sohlberg Rickard
Published: April 2024

Companies must enhance total maintenance effectiveness to stay competitive, focusing on both digitalization and basic maintenance procedures. Digitalization offers technologies for data-driven decision-making, but many maintenance decisions still lack a factual basis. Prioritizing efficiency and effectiveness require analyzing equipment history, facilitated by using Computerized Maintenance Management Systems (CMMS). However, CMMS data often contains unstructured free-text, leading to manual analysis, which is resource-intensive and reactive, focusing on short time periods and specific equipment. Two approaches are available to solve the issue: minimizing free-text entries or using advanced methods for processing them. Free-text allows detailed descriptions but may lack completeness, while structured reporting aids automated analysis but may limit fault description richness. As knowledge and experience are vital assets for companies this research uses a hybrid approach by combining Natural Language Processing with domain specific ontology and Large Language Models to extract information from free-text entries, enabling the possibility of real-time analysis e.g., identifying recurring failure and knowledge sharing across global sites.
Multi-Variate Analysis of Laser Powder Bed Fusion with 90-μm Layer Thickness of Ni-Based Superalloy Haynes 282
Authors: Swaminathan Kameshwaran , Ali Saadat , Olsson Jonas , Raza Tahira , Harlin Peter , Andersson Joel
Published: April 2024

Laser powder bed fusion (PBF-LB) processing of Haynes 282 using a layer thickness of 90-μm is studied for process capability and feasibility for increased productivity. To optimize the build rate while producing metallurgically sound parts, the effect of laser parameters on the resulting melt pool dimensions and porosity are analyzed. In a previous study, individual parameters such as laser power, scan speed and hatch distance and combination have been studied. In this study, three levels of hatch distance have been investigated while varying power and speed to same extent at all three (3) hatch distance. Similarly, the highest power level has been studied for the effect of speed and hatch distance. The melt pool dimensions, and porosity were measured in the plane parallel to the build direction. Comparison of measured responses with individual parameters provides partial trends of melt pool dimensions and porosity. It was observed that high power and/or low speed and low hatch distance increase the melt pool dimensions and reduce porosity until keyhole mode is reached. Variation of two parameters while keeping the third parameter constant was found to affect porosity due to the transition from lack of fusion type defects to keyhole porosities. The presence of dominant type of defect is identified using average feret ratio, which is the ratio of maximum length to minimum length across parallel surfaces inside a defect. It is found successful to use the combination study of process parameters and resultant type of defects to map the process to achieve minimal defects is identified for 90-μm layer thickness, through the combination study of process parameters and the resultant type of defects.
Augmented Reality Smart Glasses for Industry: How to Choose the Right Glasses
Authors: Danielsson Oscar , Ettehad Melina , Syberfeldt Anna
Published: April 2024

Augmented reality smart glasses (ARSG) have been available as a commercial product since 2015. Many potential usage areas have been identified, including industrial use. The needs from industry have evolved, with more emphasis being put on sustainability. While ARSG can help improve efficiency and sustainability, there are also similarly associated costs to their implementation and use. This paper aims to present a process for how to choose ARSG for specific use cases as assembly operator support while considering the sustainability of their implementation. A narrative review of the literature was made to identify the current understanding of the environmental impact of ARSG, as well as what has been considered in regards to ARSG being integrated into a manufacturing environment. The analysis of the literature resulted in a proposed decision process. The decision process serves as a baseline for how to guide the decision of whether ARSG could be a suitable solution and, if so, what aspects to consider in the choosing of the ARSG model. Future work includes collaboration with industry to further improve the decision process based on empirical input.
VR Interaction for Efficient Virtual Manufacturing: Mini Map for Multi-User VR Navigation Platform
Authors: Cao Huizhong , Söderlund Henrik , Despeisse Mélanie , Garcia Rivera Francisco , Johansson Björn
Published: April 2024

Over the past decade, the value and potential of VR applications in manufacturing have gained significant attention in accordance with the rise of Industry 4.0 and beyond. Its efficacy in layout planning, virtual design reviews, and operator training has been well-established in previous studies. However, many functional requirements and interaction parameters of VR for manufacturing remain ambiguously defined. One area awaiting exploration is spatial recognition and learning, crucial for understanding navigation within the virtual manufacturing system and processing spatial data. This is particularly vital in multi-user VR applications where participants’ spatial awareness in the virtual realm significantly influences the efficiency of meetings and design reviews. This paper investigates the interaction parameters of multi-user VR, focusing on interactive positioning maps for virtual factory layout planning and exploring the user interaction design of digital maps as navigation aid. A literature study was conducted in order to establish frequently used technics and interactive maps from the VR gaming industry. Multiple demonstrators of different interactive maps provide a comprehensive A/B test which were implemented into a VR multi-user platform using the Unity game engine. Five different prototypes of interactive maps were tested, evaluated and graded by the 20 participants and 40 validated data streams collected. The most efficient interaction design of interactive maps is thus analyzed and discussed in the study.
Availability and Need for Climate Footprint and Resilience Data from Suppliers in Automotive Supply Chains
Authors: Kurdve Martin , Fransson Kristin , Jonsson Patrik
Published: April 2024

This paper explores the challenges and opportunities of managing supply chain data for environmental sustainability and resilience in the automotive and vehicle manufacturing industry. It presents empirics from measuring and improving the climate footprint, based on data from interviews and workshops with original equipment manufacturers (OEMs) and suppliers, and compares concepts of resilience of supply chains. The paper focuses on the early phases of supply chain interaction, such as supplier selection and request for quota, when specific product data is often unavailable or estimated. It discusses the trade-offs and conflicts between the needs and availability of climate footprint and related supplier data, such as localization, energy supply, material supply and transportation. It also highlights the importance of data regarding recycled contents, materials, and energy in the supply chain. The paper is connected to projects funded by the EU and Vinnova that aim to enhance the competitive sustainability and resilience of the industry.
Comparative study of dose for different fluence of neutron
Authors:   L.N. Gumilyov Eurasian National University, Zhumadilov Kassym , Amangeldina Alima ,   L.N. Gumilyov Eurasian National University, Stepanenko Valerii ,   A. Tsyb Medical Radiological Research Center – Branch of the National Medical Research Radiological Center of the Ministry of Health of the Russian Federation, Hoshi Masaharu
Published: April 2024

The comparative study aims to investigate the dose received by materials exposed to different fluence of neutron radiation. The research is significant in the field of nuclear energy and radiation protection, as neutron radiation is one of the most common types of radiation produced by nuclear reactions. In this study, various materials are exposed to different fluence of neutron radiation, and the dose received by each material was measured using dosimeters. The results showed that the dose received by the materials increased with increasing fluence of neutron radiation. Furthermore, the study found that the dose-response relationship different between different materials, highlighting the importance of material selection in radiation protection. The study concludes that a better understanding of the dose-response relationship for different materials can help in the development of more effective radiation shielding materials and improve radiation safety in various applications.
Das Hegemonie-Projekt der sogenannten Clankriminalität
Authors: Struck Jens
Published: April 2024

Im vorliegenden Beitrag wird der Diskurs um sogenannte Clankriminalität vor dem Hintergrund der Diskurstheorie von Laclau respektive Laclau und Mouffe als hegemoniales Projekt betrachtet. Im Rahmen einer Analyse von Interviewdaten von Personen, denen Expertise zugeschrieben wird oder die vermeintlich mit dem Phänomen zu tun haben, wird erläutert, inwiefern und inwieweit der sicherheitsbehördliche Spezialdiskurs sich universalisieren konnte. Der Begriff Clan fungiert im Rahmen dieses hegemonialen Projekts als leerer Signifikant, der in seiner Bedeutung über- und in seinem tatsächlichen Sinngehalt unterdeterminiert ist. Indem diskursive Dislokationen aufgezeigt werden, wird darüber hinaus veranschaulicht, dass der Diskurs zu sogenannter Clankriminalität jedoch niemals vollständig geschlossen und dauerhaft fixiert sein kann.
Research on Anatomical Types and Variations of Lung Segment Bronchi Based on Artificial Intelligence 3D Reconstruction Technology
Authors: Qiao Gaofeng , Zhang Yunzeng , Shen Changming , Li Xiaofeng , Pan Yuling
Published: April 2024

Aims: To investigate the anatomic type and variation of segmental bronchus based on artificial intelligence 3D reconstruction technology. Methods: The image data of 200 patients who underwent thin-layer enhanced chest CT examination in the Department of Thoracic Surgery of Shandong Public Health Clinical Center from December 2021 to December 2022 were selected. The bronchi and blood vessels of the affected side of the lung were reconstructed according to the CT scanning data of the patients, and the anatomic types and anatomic variations of the bronchi of each lung segment on the affected side were observed and statistically analyzed. Results: There were basically four anatomical types of the right superior lobar bronchus, of which the three branching subtypes B1, B2 and B3 are the most common anatomical types. There are two types of right middle lobe bronchus, of which the B4 and B5 subtypes are the most common anatomic types. For the left lung, 4 types of segmental bronchus were found and (B1+2a+b, B1+2c), (B3a, B3b+c) was the most common anatomical type. Two types of bronchus were found in the left superior lobe of the lung. Type B4 and type B5 were the most common anatomical types. In addition, there were 3 types of bronchi in the dorsal segment of the left inferior lobe, and 3 types in the anterior, external and posterior basal segment bronchi of the left inferior lobe, among which B8, B9+B10 (57.6%) were the most common. Conclusion: The anatomical types of segmental and subsegmental bronchus are complex and varied, and there may be rare anatomical variations. Therefore, before performing relevant operations, it is necessary to be familiar with the relevant operations and the branch types of corresponding bronchus in advance to ensure the smooth operation.
Persistent Inflammation, Immunosuppression, and Catabolism Syndrome in Sepsis
Authors: Zhang Heng , Zhou Fachun
Published: April 2024

Sepsis is a life-threatening organ dysfunction resulting from a dysregulated host response to infection. Early recognition and appropriate management improve in-hospital mortality in patients with sepsis. However, many patients progress to chronic critical illness (CCI). Persistent inflammation, immunosuppression, and catabolic syndrome (PICS), a new phenotype of CCI, is characterized by chronic low-grade inflammation, host immunosuppression, and catabolic-dominant weight loss. Due to the complexity of the pathophysiologic mechanisms of PICS, there is no effective treatment available. The aim of this review is to increase understanding of the pathophysiological mechanisms of PICS in sepsis, to summarize the diagnostic criteria and potential treatments for PICS, and to help clinicians adopt more comprehensive measures to improve the long-term prognosis of patients with PICS.
Research Progress on the Relationship between Matrix Metalloproteinases and Preterm Birth
Authors: Yu Qianmei , Xu Hongbin
Published: April 2024

Premature birth is the main cause of death in children under the age of 5, and exploring the causes of premature birth has always been a hot research topic. Among them, matrix metalloproteinases (MMPS) have been confirmed to have a certain correlation with premature birth. This article summarizes the correlation between matrix metalloproteinases and preterm birth both domestically and internationally, in order to provide reference for subsequent research.
Diagnostic and prognostic value of NT-proBNP in patients with non-alcoholic fatty liver disease and acute decompensated heart failure
Authors: Misan I.A. , Arisheva O.S. , Garmash I.V. , Galochkin S. , Khutsishvili N. , Kobalava Zh.D.
Published: April 2024

To study N-terminal pro-brain natriuretic peptide (NTproBNP) levels in patients with non-alcoholic fatty liver disease (NAFLD) and acute decompensated heart failure (ADHF) and to evaluate its impact on clinical outcomes.
Uncovering the Unexpected: Rare Case of a Typical Presentation of Parathyroid Adenoma
Authors:   JSS Medical College, Mysore, India, S Aggarwal. , V Lakshman Sai ,   JSS Medical College, Mysore, India, P Pereira ,   JSS Medical College, Mysore, India, S Avarabeel ,   JSS Medical College, Mysore, India
Published: April 2024

Abstract: The incidence of primary hyperparathyroidism in India is 2.5/1000 individuals. Primary hyperparathyroidism can be caused by a non-cancerous parathyroid adenoma, hyperplasia, or, rarely, parathyroid carcinoma. Most of these patients have few or no symptoms. A correct diagnosis can be reached through clinical settings, biochemical and radiological tests, and final confirmation by histopathology of the specimen. In our case, a 75-year-old male patient with an atypical presentation of hypercalcemia presented to the hospital with complaints of nausea since 1.5 months, loss of appetite and fatigue, loss of weight, decreased sleep, and breathlessness (Grade NYHA-2) since one month, for which further evaluation was done and led to the diagnosis of primary hyperthyroidism secondary to a parathyroid adenoma. This atypical presentation of hypercalcemia and the approach in which the diagnosis was made make this case truly unique in the elderly population. Keywords: Parathyroid adenoma, atypical presentation, elderly population
Los intrusos
Authors:   Universidad de Guadalajara, Mancilla Sánchez Alma Rosa
Published: April 2024

Esta colección de relatos recuerda a las plumas clásicas del horror gótico. De identidad polifacética, se inserta en la tradición mexicana desde las narrativas de lo extraño, nutrida con las aportaciones de grandes autoras como Amparo Dávila o Guadalupe Dueñas. En estos ocho cuentos, los personajes —especialmente las mujeres, protagonistas en la mayoría de los casos— deben atravesar pesadillas y sortear ataques donde se desdibujan los límites de lo real, al tiempo que se amplía un camino oscuro y lleno de terrores cotidianos, pero también fantásticos.
Especies carismáticas
Authors:   Universidad de Guadalajara, Rosales Velázquez Aldo
Published: April 2024

Los personajes que habitan los cuentos de Aldo Rosales Velázquez presentan una familiaridad irrebatible con el lector: cada historia, por demás convencional, es una que bien podría sucederle a cualquiera. En los relatos que conforman Especies carismáticas, en los que la presencia de los animales es fundamental —desde aquellos que nos acompañan de manera cotidiana hasta los menos comunes, incluso “incómodos”—, es evidente una gran habilidad para evocar emociones complejas y contradictorias, como la nostalgia y la ternura, además de un innegable dominio de la sorpresa, los finales abiertos y la potencia visual para describir acciones, lugares e incluso pensamientos. Una prosa limpia que no se repite, de metáforas, comparaciones y símiles precisos hacen posible que cada texto, de cualidades interpretativas infinitas, se renueve y multiplique en significados tras cada nueva lectura.
Rancangan Pengukuran Kinerja Perusahaan Dengan Metode Balanced Scorecard Pada CV. Angkasa Raya Teluk Kuantan
Authors: Vivaldie Tasya , Ibrahim Mariaty
Published: April 2024

This study aims to assess performance using the balanced scorecard method across various perspectives: financial, customer, internal business processes, and growth and learning. The research employs a quantitative approach with primary and secondary data sources, involving 40 respondents from CV Angkasa Raya Teluk Kuantan employees, selected through accidental sampling. Data analysis, including validity and reliability tests, is conducted using SPSS 25. The findings indicate that (1) the financial perspective for CV Angkasa Raya Teluk Kuantan is generally positive, (2) the customer perspective reveals the company's ability to achieve customer satisfaction, (3) the internal business process perspective reflects favorable results in the areas of innovation, operations, and after-sales service, and (4) the growth and learning perspective suggests satisfactory employee satisfaction and effective training programs. The study provides a comprehensive assessment of performance measurement using the balanced scorecard method, offering insights into the company's strengths across various dimensions.
Analysis of the Effect of Accounting Information Systems on the Accuracy and Reliability of Financial Statements at Shipping Industry Companies in Surabaya
Authors: Tumbelaka Gracesheila Florencia , Eltivia Nurafni , Riwajanti Nur Indah
Published: April 2024

In the contemporary economic landscape, the indispensability of computerized systems, particularly Accounting Information Systems (AIS), is paramount for effective economic activities. This research addresses the knowledge gap surrounding the impact of AIS on the accuracy and reliability of financial statements in the shipping industry companies in Surabaya, Indonesia. The study employs a causal research design with an associative and quantitative approach, involving 57 participants related to AIS in the shipping industry. Utilizing the Integrative Framework of AIS by Romney and Steinbart (2015) and the Financial Reporting Credibility Theory by Dechow and Dichev (2002), the research aims to provide a comprehensive understanding of the relationship between AIS, accuracy, and reliability of financial statements. The findings reveal a positive correlation between AIS implementation and the quality of financial statements, emphasizing the need for effective AIS integration to enhance financial reporting in Surabaya's shipping industry. These results contribute valuable insights for practitioners, researchers, and management in optimizing AIS to support business sustainability and stakeholder confidence amidst dynamic market changes.
Pengaruh Kesadaran Wajib Pajak, Pengetahuan Pajak Bumi dan Bangunan Terhadap Kepatuhan Masyarakat dalam Membayar Pajak Bumi dan Bangunan di Desa Pasirtanjung
Authors: Nuriasilva Siti Gina
Published: April 2024

Sebagian besar pendapatan yang dipakai oleh negara untuk mendukung bisnis, menjalankan pemerintahan, dan membangun infrastruktur publik diperoleh dari pajak. Meskipun pajak bumi dan bangunan (PBB) dianggap sebagai sumber pendanaan yang potensial bagi negara, proses pengumpulannya merupakan tantangan tersendiri bagi pemerintah. Salah satu penyebab utamanya adalah rendahnya kesadaran, pengetahuan, dan kepatuhan wajib pajak. Dikarenakan itu, tujuan dari penelitian ini yaitu untuk mengevaluasi apakah penduduk Desa Pasirtanjung mematuhi kewajiban membayar PBB sesuai kesadaran mereka. Penelitian ini berfokus pada pendidikan dan kesadaran wajib pajak terhadap pajak bumi dan bangunan. Sampel penelitian terdiri dari 96 wajib pajak di Desa Pasirtanjung yang dipilih secara acak. Data yang dikumpulkan adalah data kuantitatif berupa skor atau peringkat tanggapan dari kuesioner. Informasi primer dikumpulkan melalui interaksi langsung, seperti wawancara, survei, dan analisis statistik. Analisis data menggunakan pengujian hipotesis, analisis regresi berganda, dan pengujian hipotesis standar. Hasil riset menunjukkan adanya hubungan positif diantara kesadaran wajib pajak dan tingkat kepatuhan wajib pajak di Desa Pasirtanjung. Secara spesifik, semakin tingginya kesadaran wajib pajak terhadap kewajiban membayar PBB, semakin tinggi juga tingkat kepatuhan wajib pajak. Demikian pula, pengetahuan masyarakat, khususnya wajib pajak, juga memiliki dampak positif terhadap kepatuhan mereka terhadap hukum perpajakan. Semakin tinggi pemahaman masyarakat tentang perpajakan, semakin tinggi tingkat kepatuhan wajib pajak Desa Pasirtanjung
Pengaruh Penetapan Harga, Kelompok Referensi dan Gaya Hidup Terhadap Keputusan Pembelian (Studi Kasus Pada Candu Kopi di Jalan Bangau Sakti Pekanbaru)
Authors: Azira Rana , Fadli Mashur
Published: April 2024

Penelitian ini ditujukan guna mengetahui pengaruh penetapan harga, kelompok referensi dan gaya hidup terhadap keputusan pembelian (Studi Kasus Pada Candu Kopi Jalan Bangau Sakti, Pekanbaru). Persaingan yang begitu banyak sekarang ini, maka setiap perusahaan perlu menyusun strategi pemasaran. Perusahaan akan berusaha mempertahankan konsumen sebelum direbut oleh perusahaan lain yang menawarkan produk serupa. Untuk mempertahankan konsumen yang ada, setiap perusahaan tentunya mempunyai strategi pemasaran yang berbeda dengan kompetitornya dengan harapan agar perusahaan tersebut dapat bertahan dan memiliki keunggulan dibandingkan produk pesaing di pasaran. Jika perusahaan ingin memenangkan persaingan, maka kuncinya adalah berupaya untuk mempengaruhi keputusan pembelian. Kini model bisnis telah berubah yang awalnya berorientasi pasar, sekarang menjadi berorientasi konsumen, yang mengharuskan perusahaan memenangkan persaingan dengan mempertahankan konsumen. Melihat hal tersebut menuntut perusahaan untuk mengetahui berbagai keperluan serta harapan konsumen serta mengetahui sikap saat mengambil keputusan pembelian. Memahami perilaku konsumen ialah faktor penting bagi setiap perusahaan untuk mempengaruhi kemauan pembeli ketika melakukan pembelian produk yang dijual serta dibutuhkannya. Begitupula dalam situasi peningkatkan penjualan, perusahaan perlu membuat strategi yang sesuai supaya bisa memberi pengaruh konsumen saat melaksanakan pengambilan keputusan pembelian. Keputusan pembeli ketika melakukan pembelian produk bisa saja terjadi karena pengaruh lingkungan yang ada, salah satunya bermula dari kebiasaan atau gaya hidup masyarakat. Adapun metode penelitian yang dipakai ialah statistik deskriptif dan kuantitatif menggunakan model penelitian explanatory research. Kemudian untuk sampel yang dipakai sejumlah 98 responden yang ditetapkan memakai purposive sampling serta memakai kuesioner sebagai instrumen pengumpul data. Hasil penelitian ini mengungkapkan penetapan harga menghadirkan pengaruh terhadap keputusan pembelian, kelompok referensi menghadirkan pengaruh terhadap keputusan pembelian, gaya hidup menghadirkan pengaruh terhadap keputusan pembelian dan penetapan, kelompok referensi , gaya hidup menghadirkan pengaruh terhadap keputuan pembelian pada Candu Kopi Pekanbaru.
Pengaruh Pelatihan Dan Pengembangan Sumber Daya Manusia Terhadap Kinerja Karyawan Pada PT. PLN Icon Plus SBU Pekanbaru
Authors: Azizah Duta Rahmathul , Karneli Okta
Published: April 2024

Sumber daya manusia merupakan elemen kritis dalam kesuksesan dan pertumbuhan dalam suatu perusahaan. Sumber daya manusia dengan segala fungsinya yang esensial merupakan aset penting dan tak tergantikan yang menjadi pendorong pertumbuhan dan kesuksesan perusahaan dalam menghadapi tantangan dunia bisnis modern yang semakin kompleks.Penelitian ini dilaksanakan pada PT. PLN Icon Plus SBU Pekanbaru. Tujuan penelitian yakni guna memahami pengaruh pelatihan dan pengembangan sumber daya manusia terhadap kinerja karaywan di PT. PLN Icon Plus SBU Pekanbaru. Pelatihan dan pengembangan sumber daya manusia menjadi variabel independent sedangkan Kinerja karyawan menjadi variabel dependent. Permasalahan pada penelitian ini yakni kinerja karyawan yang tidak mengalami perkembangan signifikan dan cenderung stagnan selama beberapa tahun terakhir. Sampel dalam penelitian ini ditetapkan sejumlah 86 responden dari 109 populasi  diukur dengan memanfaatkan rumus Slovin. Jenis penelitian ini adalah penelitian kuantitatif dengan menggunakan teknik pengumpulan data kusioner atau angket.Data yang didapati dari hasil kuesioner yang disebarkan memanfaatkan teknik simple random sampling yang berikutnya diolah guna selanjutnya dikaji dengan program SPSS 24. Pada hasil pengujian yang dilaksanakan memperlihatkan pelatihan memiliki pengaruh terhadap kinerja karyawan, dimana thitung = 8.209 > ttabel 1.988 serta sig 0.000 < 0.05, selanjutnya pengembangan sumber daya manusia mempunyai pengaruh terhadap kinerja karyawan, dimana thitung = 7.643 > ttabel 1.988 serta sig 0.000 < 0.05, serta pelatihan dan pengembangan sumber daya manusia terhadap kinerja karyawan, dengan fhitung 37.159 > ftabel 3.11, serta sig 0.000 < 0.05.
The Influence of Workload Aad Perceived Behavioural Control on Performance Through Motivation in Satlantas Members Kampar Police
Authors: Norawati Suarni , Syamra Rahmad
Published: April 2024

Satlantas is one of the implementing units at the Kampar Police with the main task of providing services, educational guidance to the community regarding traffic regulations. Therefore, the performance of members of the Kampar Police Traffic Unit needs to be improved and it is necessary to know the factors that influence this performance. This research aims to determine the influence of workload and perceived behaviour control on member motivation and performance, as well as to see the influence of workload and perceived behaviour control through motivation on member performance. The sample for this research was 135 respondents with Smart PLS data analysis. The study reveal that Workload and perceived behavior control were found to have an empirically demonstrated significant impact on work motivation. Workload was also found to have a significant impact on performance, although perceived behavior control variables did not show a significant impact on performance. The study's findings also indicated that motivation had a significant impact on performance, and that workload and perceived behavior control influence performance through the work motivation of Kampar Police Traffic Unit members.
Pengaruh Kedisiplinan, Keselamatan dan Kesehatan Kerja Terhadap Produktivitas KerjaKaryawan Pada PT JMS Batam
Authors: Zega Otinia , Nainggolan Nora Pitri
Published: April 2024

The purpose of this study is to anayze the influence of work discipline, safety and heath partialy and simultaneously on the work of employees of PT. JMS Batam. This study uses a quantitative approach. The population in this study is al employees in Burret PA in 2022 at PT. JMS Batam has 160 employees. Determining the number of samples using saturated samples from the entire population and the sampling technique using incidenta sampling so that the number of questionnaires returned was 120 questionnaires, thus the sample used in this study totaed 120 samples. This study shows conclusively that: (1) Work discipline partialy has a significant effect on employee work productivity, with a t count of 8.216 > 1.980 from t table and obtains a significance vaue of 0.00 <0.05. (2) Occupationa safety and heath partialy have a significant effect on employee work productivity, with a t count of 5.995 > 1.980 from t table and obtain a significance vaue of 0.00 <0.05. (3) Work discipline, occupationa safety and heath simultaneously have a significant effect on employee work productivity, with a caculated f vaue of 103.291 > 3.09 from ftable and obtain a significance vaue of 0.00 <0.05. (4) The magnitude of the influence of work discipline, occupationa safety and heath on the work productivity of employees of PT. JMS Batam by 0.764 or 76.4%. and the remaining 23.6% is explained by other variables outside this research model.
Effects of mindfulness training on cognition and wellbeing in healthy older adults
Authors: Mallya Sasha , Fiocco Alexandra
Published: April 2024

Adults over the age of 65 years are now the fastest growing segment of the Canadian population. Although individual differences exist, aging is commonly associated with impairments in executive function and episodic memory. Previous studies have shown that mindfulness-based stress reduction (MBSR) can improve cognitive function in healthy younger adults, but no studies have yet examined this effect in older adults. The present study investigated the effectiveness of MBSR on improving executive function and episodic memory in older adult as well as its effectiveness in improving perceived stress and well-being. Ninety-seven healthy older adults were randomly assigned to either MBSR (n = 57) or an active control group (n = 40). It was hypothesized that compared with the control group, the MBSR group would display significant improvements in measures of executive function, episodic memory, mindfulness, mood, self-esteem, and quality of life. No clinically meaningful changes were found on any variable. In light of these results, the value of MBSR for this population is discussed.

 
A systematic review of existing peripheral biomarkers of cognitive aging: Is there enough evidence for biomarker proxies in behavioral modification interventions?
Authors: Fiocco Alexandra , Krieger Laura , D'Amico Danielle , Parrott Matthew D. , Laurin Danielle , Gaudreau Pierrette , Greenwood Carol , Ferland Guylaine
Published: April 2024

Peripheral biomarkers have shown significant value in predicting brain health and may serve as a useful proxy measurement in the assessment of evidence-based lifestyle behavior modification programs, including physical activity and nutrition programs, that aim to maintain cognitive function in late life. The aim of this systematic review was to elucidate which peripheral biomarkers are robustly associated with cognitive function among relatively healthy non-demented older adults. Following the standards for systematic reviews (PICO, PRIMSA), and employing MEDLINE and Scopus search engines, 222 articles were included in the review. Based on the review of biomarker proxies of cognitive health, it is recommended that a comprehensive biomarker panel, or biomarker signature, be developed as a clinical end point for behavior modification trials aimed at enhancing cognitive function in late life. The biomarker signature should take a multisystemic approach, including lipid, immune/inflammatory, and metabolic biomarkers in the biological signature index of cognitive health.

 
In Defense of Immoralism
Authors: Herbert Claire Bronwen
Published: April 2024

This paper investigates whether an ethical flaw in an artwork can be an aesthetic merit. I explore two versions of immoralism from Eaton and Kieran. I will defend the immoralist claim that artworks containing rough heroes are ethically flawed. I will then argue that an indirect connection between an ethical flaw and aesthetic merit is sufficient for immoralism, so long as it is a necessary connection. On this understanding of immoralism, I will argue that Eaton and Kieran are both successful in showing that an ethical flaw in an artwork can make it aesthetically better.
Investigation and response to an outbreak of Neisseria meningitidis serogroup Y ST-1466 urogenital infections, Australia
Authors: Lahra MM , Latham NH , Templeton DJ , Read P , Carmody C , Ryder N , Ellis SE , Madden EF , Parasuraman A , Wells J , Sheppeard V , Armstrong BH , Holland J , Pendle S , Sherry N , Leong L , Selvey CE , Van Hal SJ
Published: April 2024

In 2023, an increased number of urogenital and anorectal infections with Neisseria meningitis serogroup Y (MenY) were reported in New South Wales (NSW). Whole genome sequencing (WGS) found a common sequence type (ST-1466), with limited sequence diversity. Confirmed outbreak cases were NSW residents with a N. meningitidis isolate matching the cluster sequence type; probable cases were NSW residents with MenY isolated from a urogenital or anorectal site from 1 July 2023 without WGS testing. Of the 41 cases, most were men (n = 27), of whom six reported recent contact with women in sex work. Five cases were men who have sex with men and two were women in sex work. Laboratory alerts regarding the outbreak were sent to all Australian jurisdictions through the laboratories in the National Neisseria Network. Two additional states identified urogenital MenY ST-1466 infections detected in late 2023. Genomic analysis showed all MenY ST-1466 sequences were interspersed, indicative of a multi-jurisdictional outbreak. The incidence of these infections remains unknown, due to varied testing and reporting practices both within and across jurisdictions. Isolates causing invasive meningococcal disease (IMD) in Australia are typed, and there has been no MenY ST-1466 IMD recorded in Australia to end of March 2024. Concerns remain regarding the risk of IMD, given the similarity of these sequences with a MenY ST-1466 IMD strain causing a concurrent outbreak in the United States of America.
A severe case of swimmer’s itch in Victoria, Australia with bullous eruption
Authors: Sangiorgio Michael , Liu Karen , Lau Lachlan , Krones Charlotte , Tramontana Adrian , Molton James , Nirenberg Alex
Published: April 2024

Cutaneous schistosomiasis (swimmer’s itch) is an itchy maculopapular rash that follows skin penetration by cercariae of nonhuman schistosomes, during fresh or brackish water exposure. It is typically a mild skin reaction that settles in one to three weeks. Here we describe a case of severe swimmer’s itch acquired in Victoria, Australia, with widespread bullous lesions on water-exposed areas of skin. This case presented a diagnostic challenge and is unique given the severity of the reaction and the geographic occurrence; the condition rarely causes bullae, and to date has been reported only in more northern latitudes of Australia. With climate change trends, swimmer’s itch is likely to become increasingly prevalent in more temperate regions, illustrating the importance of clinician awareness of this condition.
Dr. Humberto Fernández Morán
Authors: Oñate Omaira
Published: April 2024

Humberto Avelino Fernández Morán Villalobos (1924- 1999) fue doctor en medicina, científico, investigador biofísico y docente.  Nacido en Venezuela, Maracaibo Estado Zulia, el 18 de febrero de 1924.  Este año 2024 se cumplen los primeros 100 años de su nacimiento. Hijo de Luis Fernández Morán y Elena Villalobos.  Comparte su formación académica y vida personal entre su patria Venezuela, EEUU y Europa.  Muere en Estocolmo Suecia, el 17 de marzo de 1999, producto de una neurisma cerebral. [1] [3] Es un venezolano extraordinario, un científico grande, inventor del bisturí o cuchilla de diamante, instrumento para la ultra microtomia, corte ultrafino de materiales biológicos y metálicos que permitió observar estructuras subcelulares, invención que ha impactado significativamente campos médicos y científicos mundiales, de aplicación en la cirugía oftálmica   y de alta precisión, hasta con muestras de rocas lunares. Profesor e investigador en la Universidad Central de Venezuela y en Universidades de Estados Unidos y Suecia. Investigador en la NASA para el proyecto APOLO en el análisis de las rocas lunares. [5] [7].
Entrevista a Katya S. Romeleroux, directora del Laboratorio de Botánica Sistemática. Pontificia Universidad Católica de Ecuador
Authors: Berbey Álvarez Aránzazu
Published: April 2024

La Dra. Romoleroux es una docente, investigadora y científica ecuatoriana. Profesora principal a tiempo completo en la Escuela de Ciencias Biológicas de la Pontificia Universidad Católica del Ecuador y ha sido curadora y directora del Herbario QCA, además es directora del Laboratorio de Botánica Sistemática de la PUCE. Es miembro de la Academia de Ciencias de América Latina, de la Asociación Latinoamericana de Botánica, de la Sociedad de Curadores de Herbarios y miembro fundador de la Academia de Ciencias del Ecuador. Ganó una primera beca en el año 1989, para estudiar Biología Tropical y Recursos Naturales en la Universidad de Aarhus (Dinamarca), donde obtuvo su Ph.D. con otra beca de la Agencia Danesa de Desarrollo Internacional. En el 2002 realizó un posdoctorado en la Universidad Ludwig Maximilian de Múnich (Alemania) con una beca de la Fundación Alexander von Humboldt y en el 2022 ganó otra beca de corta estadía de la Fundación Alexander von Humboldt en la misma universidad.
Klarhet för allmänheten
Authors: Bjelkmark Östlund Wilma , Forssell Alice , Lövgren Olofsson Kajsa
Published: April 2024

Vi är tre studenter som läser vår sista termin på programmet Språk, Litteratur och Medier på Linköpings Universitet. Denna blogg är en del av vår medieutbildning.
Advances in fecal microbiota transplantation for the treatment of diabetes mellitus
Authors: Zhang Juan , Wang Honggang , Liu Ying , Shi Min , Zhang Minna , Zhang Hong , Chen Juan
Published: April 2024

Diabetes mellitus (DM) refers to a group of chronic diseases with global prevalence, characterized by persistent hyperglycemia resulting from various etiologies. DM can harm various organ systems and lead to acute or chronic complications, which severely endanger human well-being. Traditional treatment mainly involves controlling blood sugar levels through replacement therapy with drugs and insulin; however, some patients still find a satisfactory curative effect difficult to achieve. Extensive research has demonstrated a close correlation between enteric dysbacteriosis and the pathogenesis of various types of DM, paving the way for novel therapeutic approaches targeting the gut microbiota to manage DM. Fecal microbiota transplantation (FMT), a method for re-establishing the intestinal microbiome balance, offers new possibilities for treating diabetes. This article provides a comprehensive review of the correlation between DM and the gut microbiota, as well as the current advancements in FMT treatment for DM, using FMT as an illustrative example. This study aims to offer novel perspectives and establish a theoretical foundation for the clinical diagnosis and management of DM.
Comparison of infection and complication rates associated with transvenous vs. subcutaneous defibrillators in patients with stage 4 chronic kidney disease: a multicenter long-term retrospective follow-up
Authors: Schiedat Fabian , Meuterodt Benjamin , Prull Magnus , Aweimer Assem , Gotzmann Michael , O’Connor Stephen , Perings Christian , Korth Johannes , Lawo Thomas , El-Battrawy Ibrahim , Hanefeld Christoph , Mügge Andreas , Kloppe Axel
Published: April 2024

Background

Patients with progressive chronic kidney disease (CKD) are at higher risk of infections and complications from cardiac implantable electronic devices (CIED). In patients with a primary or secondary prophylactic indication, implantable cardiac defibrillators (ICD) can prevent sudden cardiac deaths (SCD). We retrospectively compared transvenous-ICD (TV-ICD) and intermuscularly implanted subcutaneous-ICD (S-ICD) associated infections and complication rates together with hospitalizations in recipients with stage 4 kidney disease.

Methods

We retrospectively analyzed 70 patients from six German centers with stage 4 CKD who received either a prophylactic TV-ICD with a single right ventricular lead, 49 patients, or a S-ICD, 21 patients. Follow-Ups (FU) were performed bi-annually.

Results

The TV-ICD patients were significantly older. This group had more patients with a history of atrial arrhythmias and more were prescribed anti-arrhythmic medication compared with the S-ICD group. There were no significant differences for other baseline characteristics. The median and interquartile range of FU durations were 55.2 (57.6–69.3) months. During FU, patients with a TV-ICD system experienced significantly more device associated infections (n = 8, 16.3% vs. n = 0; p < 0.05), device-associated complications (n = 13, 26.5% vs. n = 1, 4.8%; p < 0.05) and device associated hospitalizations (n = 10, 20.4% vs. n = 1, 4.8%; p < 0.05).

Conclusion

In this long-term FU of patients with stage 4 CKD and an indication for a prophylactic ICD, the S-ICD was associated with significantly fewer device associated infections, complications and hospitalizations compared with TV-ICDs.