bluuebunny/crossref_metadata_2025 huggingface dataset:
“Em mangas de camisa”
Authors: Tin Emerson
Published: July 2018

Resumo: O objetivo deste artigo é, a partir de exemplos extraídos da correspondência de quatro escritores brasileiros do século XX (Monteiro Lobato, Mário de Andrade, Graciliano Ramos e Fernando Sabino), proceder ao levantamento de algumas considerações esparsas sobre o ato de escrever cartas, que compreendem não só comentários sobre a materialidade do ato em si (por exemplo, o papel ou a tinta empregados, o uso da máquina de escrever), mas também sobre as possibilidades e impossibilidades proporcionadas pelo próprio gênero epistolar (a ideia da carta como uma “conversa por escrito”, os lugares-comuns e as limitações do gênero). Pretende-se, assim, entender como a escrita de cartas se construiu ao longo do século passado, a despeito da praticamente inexistente produção de obras teóricas para a orientação da escrita de cartas, ao contrário do que se viu nos séculos anteriores.Palavras-chave: cartas brasileiras; século XX; correspondência; escrita de cartas; epistolografia.Abstract:The aim of this article is, by drawing on the correspondence exchanged among four Brazilian writers of the twentieth century (Monteiro Lobato, Mário de Andrade, Graciliano Ramos and Fernando Sabino), to survey some scant considerations about the act of writing letters, which include not only comments on the materiality of the act itself (e.g. the paper or ink employed and the use of the typewriter), but also on the possibilities and impossibilities provided by the epistolary genre (the idea of the letter as a “written conversation”, the commonplaces and limitations of the genre). It is intended, therefore, to understand how the writing of letters was built during the last century, in spite of the nearly nonexistent production of theoretical works for the analysis of letter writing, in contrast to what was seen in the previous centuries.Keywords: Brazilian letters of the twentieth century; correspondence; letter writing; epistolography.
Obras involuntárias, olhares extemporâneos (edições de correspondência de escritores brasileiros em 2017)
Authors: Moraes Marcos Antonio de
Published: July 2018

Resenha do livro Obras involuntárias, olhares extemporâneos (edições de correspondência de escritores brasileiros em 2017)
An observational study of the outcome between early excision and resurfacing of deep thermal burns with the results of traditional dressing at a tertiary care center
Authors: Nathani Neeraj , Pal Lalmani , Kumar Yogesh , Siddiqui Md. Qamar
Published: July 2018

Background: Patients hospitalized with burn wounds face special challenges. Host, environmental, and organism factors increase burn patient risk of developing infection and may prolong the course of infection, once acquired. Host immune, circulatory, and respiratory systems are often compromised. Most admitted burn patients have third-degree or full-thickness burns, requiring granulation and/or grafting for acceptable repair. The zone of necrosis surrounding the burned tissue may continue to expand for up to 48 hours after injury, enlarging and deepening the path for pathogen invasion. Hospital environments may contain resistant strains of pathogenic organisms. Many studies have proved early excision and grafting of burn to be the better modality of treatment when compared with other methods like conservative dressing with antibiotics etc. This study was conducted to observe that early excision is better in patients having burn surface area less than 30% when compared to conservative dressing.Methods: This is an observational study of 60 patients out of which 30 received early resection and remaining 30 were treated with conservative dressing by antibiotics and other topical ointments.Results: In this study, observation was made that early resection of burns involving less than 30% body surface area has better outcomes in various parameters than conservative dressing and this has been statistically proven.Conclusions: This study concludes that early excision and resurfacing of deep burns is beneficial than the traditional dressing of burn wounds and saves time, resources and also gives a better outcome.
MULHERES NA POLÍTICA: HISTÓRIAS DE PROTAGONISMO FEMININO NA AMAZÔNIA E A LUTA CONTRA O PRECONCEITO DE GÊNERO NAS INSTÂNCIAS DE PODER POLÍTICO
Authors: Souza Michelle Rabelo
Published: July 2018

As mulheres brasileiras conquistaram o direito ao voto em 1932, tendo sua consolidação em 1934.  Somente em 1995, com a provação da Lei 9.100, de 29 de setembro, obtiveram a garantia de cota de 20% de gênero nas chapas das candidaturas. Após dois anos, em 1997, foi aprovada a Lei 9.504, passando a cota para 30%. No entanto, em qualquer aspecto avaliado, a conclusão é sempre a mesma,  houve ganhos, mas em ritmo muito inferior ao desejado. Há pelo menos duas suposições a serem consideradas sobre esta problemática. A primeira está relacionada com o sistema político de cotas brasileiro que é extremamente conservador em relação às mulheres, de face androcêntrica e machista. A outra suposição está vinculada à situação das mulheres dentro dos partidos políticos, as quais possuem posição de coadjuvantes, assumindo um papel subalternizado, na medida em que não ascendem ao cargo de presidente de seus partidos. Diante desse quadro de desigualdade, o presente estudo tem como objetivo descrever o protagonismo político de quatro mulheres junto ao parlamento brasileiro. Para atingirmos os objetivos aqui propostos, realizamos entrevistas semiestruturada a quatro mulheres (duas ex-parlamentares e duas parlamentares) para sabermos sobre a atuação política de cada uma junto ao parlamento. Dos múltiplos resultados apresentados pelo estudo, conclui-se que a mulher na Amazônia tem uma longa história de participação política e que independente das diferentes décadas de atuação, foram capazes de enfrentar todas as formas de preconceito dentro dos partidos políticos e da própria casa parlamentar para se firmarem enquanto parlamentares.
POLÍTICAS DE FORMAÇÃO CONTINUADA EM SERVIÇO: PERCEPÇÃO DE PROFESSORES EM ESTAGIO PROBATÓRIO
Authors: Pereira Rosimeri da Silva , Trindade Izoni Souza
Published: July 2018

O artigo trata do olhar docente sobre formação continuada vinculada ao processo de EstágioProbatório, tendo como referência o Programa de Formação de Profissionais da EducaçãoPública (PFPEP) instalado na rede estadual de ensino amazonense. O estudo se ampara nametodologia qualitativa tendo por base a observação de entrevistas desenvolvidas em 5 escolassediadas num dos municípios do Estado do Amazonas. A investigação apresenta como eixo oconjunto de legislação Estadual e Federal, as prerrogativas do Conselho Nacional de Educação,o Programa de Formação Continuada em curso e finalmente a percepção do professorado.Conclui-se que embora tal Política tenha como ponto de partida a ideologia da melhoria dequalidade do ensino por meio do monitoramento e formação dos profissionais da educação, hálimites em ralação ao curso de formação continuada em pauta bem como às condições objetivasde funcionamento das escolas públicas como um todo.
COMPETÊNCIAS NA FORMAÇÃO DE PROFESSORES: DA LDB À BNCC
Authors: Maquiné Gilmara Oliveira , Azevedo Rosa Oliveira Marins
Published: July 2018

Este artigo elenca aspectos das competências na formação de professores encontrados desde a Lei de Diretrizes Bases da Educação (LDB) até a Base Nacional Comum Curricular (BNCC). O objetivo é evidenciar as competências em documentos que norteiam a educação no Brasil e os reflexos destas publicações na formação docente. A investigação foi conduzida na disciplina Fundamentos para a Formação de Professores no Ensino Tecnológico do Mestrado Profissional em Ensino Tecnológico do Instituto Federal de Educação, Ciência e Tecnologia do Amazonas. Está organizado em três seções, além da introdução e das considerações finais. A primeira seção apresenta conceituações de competências identificadas nas literaturas; a segunda destaca os aspectos de competências identificados na LDB; a terceira aponta as características de competências na BNCC. Os resultados do estudo indicam que existe uma tendência na discussão de competências para a formação de professores que requer a necessidade de discussão aprofundada sobre a temática, em particular, considerando a publicação da BNCC.
PERLINDUNGAN HUKUM TERHADAP HAK ASASI ANAK YANG MENJADI KORBAN KEKERASAN
Authors: Azkia Zuraidah , Is Muhamad Sadi
Published: July 2018

Child rights are an integral part of human rights so that the government must develop the obligation to protect, fulfill and respect the rights of children especially the rights of children who are victims of violence, because violence against children especially in Indonesia is increasing recently. Therefore, the form of legal protection against the rights of children who are victims of violence can be given in a repressive form that is done in a systematic way, through a series of programs, stimulation, training, education, prayer guidance, games and can also be provided through legal aid called advocacy and child protection laws. While the concept of legal protection of child rights in the future must do law reform of child protection system in Indonesia with the aim to give justice, certainty and benefit to children in Indonesia in particular so as to protect and guarantee the rights of children who become victims violence. In order for child protection law in Indonesia in the future to be able to really give protection to child rights which become victims of violence, then child protection law must be free from humanity principle based on human rights.
PROBLEMATIKA PENGELOLAAN TANAH WAKAF PRODUKTIF BERBASIS MASJID
Authors: Rochmiyatun Siti
Published: July 2018

Waqf is one of the most highly recommended worship in the teachings of Islam, to be used by someone as a means of distributing gift by Allah SWT to him. The practice of waqf is of great value to socio-economic, cultural life. Management of Waqf land productively mosques in Palembang City has been implemented, but in general most mosques still do not manage Waqf land mosque productively. The problematic for managing the Waqf land of a mosque productively are, 1. The legal substance (AIW substance of Waqf land) may impede implementation; 2. Understanding of some Nazhir/ Mosque management on the management of productive Waqf land is still low; 3. The general understanding of the community about the management of productive Waqf land is still low; 4. The ability of Nazhir/ Managers to manage and develop productive enterprises is still low; 5. Community culture does not encourage the implementation of productive waqf land management; 6. Community law culture is a legal awareness to implement the law, especially regarding the management and development of Waqf land productively low. Efforts that can be done to overcome the problematic is the Office of the Ministry of Religious Affairs and BWI, BWI Representative of South Sumatra should increase the socialization and comprehensive training of productive waqf management to mosque nazhir and the community around the mosque.
POLA REKRUTMEN POLITIK BERDASARKAN IDEOLOGI PARTAI POLITIK DALAM SISTEM KETATANEGARAAN INDONESIA
Authors: Suhaimi Else
Published: July 2018

Political recruitment is a process of selecting and selecting a person or several members of the community to occupy and exercise certain political roles as cadres of political parties, legislators, as president and vice president and as regional head. In the Indonesian state system, this political recruitment is left to political parties. The rise of political parties as a result of freedom of association and assembly on the one hand is a reflection of democracy but on the other hand the large number of political parties will give rise to increasingly tight competition between political parties. The increasing competition makes political actors easily trapped in political pragmatism. Political pragmatism as a short-term orientation of political actors to win political competition is power. Power as the ultimate goal of the political competition. Political pragmatism has had a significant impact on the formation of pragmatic recruitment patterns. The pattern of pragmatic recruitment has spawned many problems, especially issues related to the quality of recruitment results. One of them is that many of the political elites are facing legal problems such as corruption and so on. Under these conditions emerged initiatives to present a systematic and structured pattern of political recruitment. One of the indications is that political recruitment is based on the ideology of political parties. The ideology of a political party is broadly divided into recruitment based on Islamic ideology (religion) and other ideologies such as nationalism. the closer the party ideology to the party recruitment pattern will result in quality recruitment and visionary cadres. on the contrary, the further distance the party ideology with the party recruitment pattern will result in a pragmatic recruitment. The results of recruitment have a close relationship with the quality of products produced, especially product legislation.

 

Kata Kunci : pola rekrutmen, partai politik, sistem ketatanegaraan
ASIMILASI ISLAM DENGAN BUDAYA LOKAL DI NUSANTARA
Authors: Mukhlishin Ahmad , Jamil Muhammad , Maba Aprezo Pardodi
Published: July 2018

Islam as a religion that is present in all tribes in the archipelago as a value system that integrates with the local culture, so this is often seen by people outside the tribe with Islam Minangkabau, Javanese Islam, and so on. The accumulation of cultures with various intercourses called multiculturalism. But the great possibility both can play an important role in shaping a new culture, because there is a dialogue between the orders of religious values ​​that become the idealism of a religion with local cultural values. As a system of knowledge, religion is a belief system that is full of moral teachings and guidance of life must be studied, examined and then practiced by man in his life. In this case religion provides clues about the "good and bad that are inappropriate and inappropriate" and the "right and inappropriate". Religious values ​​can form and develop human behavior in their daily lives. It is therefore not difficult to understand that having a common symbol is the most effective way to strengthen unity among religious followers. This is because the meaning of these symbols deviates far from the intellectual definitions so that the symbol's ability to unite is greater, whereas the intellectual definition causes division. Symbols can be shared because they are based on feelings that are not formulated too tightly. That is why Islam has historically come to various parts of the archipelago with a relatively peaceful atmosphere with almost no tension and conflict. Islam can easily be accepted by society as a religion that brings peace, even though at that time people have been religious and have their own belief in animism, dynamism, Hinduism and Buddhism. The spread of Islam causes the emergence of Islamic patterns and variants that have uniqueness and uniqueness. It must be realized that the existence of Islam in Indonesia is never single.
Rios Urbanos: O Caso do Rio Icaraí – Niterói/RJ
Authors: Holzer Rainer , Araujo Eloisa Carvalho de
Published: July 2018

Este trabalho teve como objetivo analisar a variabilidade espacial e temporal do Índice de Estado Trófico (IET) em sete pontos de amostragem e em diferentes sub-bacias do rio Verruga, localizado entre os municípios de Vitória da Conquista e Itambé, região sudoeste da Bahia, durante o período de dez meses de monitoramento, em escala de tempo mensal. A determinação da concentração de fósforo total na água foi feita de acordo com as recomendações da APHA (2005). Com base nos resultados obtidos, conclui-se que as águas do rio Verruga apresentam estado hipereutrófico.
Levantamento dos processos intervenientes na concentração de material particulado no município de Campos dos Goytacazes/RJ
Authors: Faria Fernanda Do Nascimento , Barbosa Kargean Vianna , Ribeiro Osmane Pessanha
Published: July 2018

Foram analisados os dados de monitoramento do ar da região de Campos dos Goytacazes/RJ referentes aos anos de 2012, 2013 e 2015, a partir da coleta de valores de massa do material particulado suspenso, através dos amostradores de grande volume (Hi-Vol) do INEA – Instituto Estadual do Ambiente, e se discriminaram aqueles fatores consideravelmente influentes: fluxo de veículos automotores; incremento populacional; ocorrência de queimadas em canaviais; e ainda fatores climatológicos (índices de precipitações obtidos por meio do INMET – Instituto Nacional de Meteorologia). Foi efetuado tratamento estatístico para observações de tendências e preenchimento de eventuais ausências de dados. Verificou-se que o regime de chuvas exerceu importante papel no assentamento do particulado em suspensão, estabelecendo uma razão inversamente proporcional. O aumento da população no município, associado ao aumento de veículos circulantes, significa maior quantidade de material particulado emitido e disperso pelo efeito de turbulência dos automóveis. Também foram alocados espacialmente os focos e períodos preferenciais de queimadas, percebendo-se que há influências sobre as concentrações de material particulado suspensos no ar. Notou-se ainda diferenças entre os valores encontrados entre os dois pontos de coleta, isso possivelmente devido às influências e peculiaridades locais.
Raising Awareness and Addressing Elder Abuse in the LGBT Community: An Intergenerational Arts Project
Authors: Robson Claire , Gutman Gloria , Marchbank Jen , Blair Kelsey
Published: July 2018

This paper reports on a collaborative digital arts project conducted with LGBT youth and seniors in Vancouver, British Columbia, Canada, funded by the B.C. Council to Reduce Elder Abuse and conducted by faculty members and a doctoral student from Simon Fraser University. In the project, youth and seniors worked together to produce the first Canadian materials on LGBT elder abuse—three digital videos and five informational posters. We report on the methods used to produce and disseminate the materials, and as we reflect on the project’s outcomes, we consider both the challenges and potential of digital literacies in this context.
“Um carro a menos”: análise sobre a atuação do movimento cicloativista na disputa sobre a política de mobilidade urbana de Porto Alegre
Authors: Oliveira Danielle Soares Pires de , Silva Marcelo Kunrath
Published: July 2018

Abordando a relação entre os movimentos sociais e as políticas públicas, o artigo analisa a atuação do movimento cicloativista na sua tentativa de incidir na política de mobilidade urbana de Porto Alegre. A questão de pesquisa que orienta a argumentação desenvolvida é: como as redes heterogêneas que conformam os movimentos sociais se estruturam e se transformam, ao longo do tempo, a partir de sua atuação (ou tentativa de atuação) nos diferentes fluxos que constituem o processo de construção das políticas públicas? A análise se baseia em entrevistas com cicloativistas e atores da burocracia estatal envolvidos com a política de mobilidade urbana, além de pesquisa documental.
A ambivalência do pensamento de José Leite Lopes sobre Desenvolvimento em “Ciência e Libertação”
Authors: Peron Alcides Eduardo dos Reis , Furlan Tildo
Published: July 2018

Dotado de uma exuberante biografia, José Leite Lopes viveu e protagonizou o processo de institucionalização da ciência no Brasil e nos países latino-americanos. Assim, o objetivo desse artigo é realizar uma breve investigação acerca do pensamento em Ciência, Tecnologia e Sociedade desenvolvido pelo físico, atentando para o momento em que as suas observações se aproximam das realizadas pelo PLACTS (Pensamento Latino Americano em Ciência, Tecnologia e Sociedade). Para tanto, exploraremos as principais características do PLACTS, destacando a essência do pensamento de Leite Lopes. A partir disso, nos debruçaremos sobre as perspectivas de Celso Furtado acerca do desenvolvimento subordinado e subdesenvolvimento para analisarmos as posições de Leite Lopes.
Securing Security in Education: The Role of Public Theology and a Case Study in Global Jihadism
Authors: Lovat Terence
Published: July 2018

The article mounts an argument for public theology as an appropriate if not vital adjunct to contemporary education’s addressing of security issues in light of current world events with indisputable religious and arguably quasi-theological foundations. It will briefly expound on the history of thought that has marginalized theology as a public discipline and then move to justify the counter view that the discipline, at least in the form of public theology, has potential to address matters of such public concern in a unique and helpful way. The article will culminate with an exploration of Global Jihadism as a case study that illustrates the usefulness of public theology in understanding it better and so allowing for a response with potential to be more informed and security-assured than is commonly effected.
Pengembangan Permainan Tebak Soal Dalam Power Point Untuk Meningkatkan Pengetahuan Kognitif Mahasiswa Mata Kuliah Pendidikan PKN Sd Program Studi PGSD STKIP Bina Insan Mandiri
Authors: Prameswari Noviardani Kartika
Published: July 2018

This study aims to develop the learning game of PKN elementary education courses of fun learning materials in the 2nd semester students. The use of guessing games through power points in learning can motivate students to high learning spirit. Using the game guess the problem in the group can know the cognitive learning outcomes of students when students are doing the game is accompanied by lecturers. This research is a device development research that used in game in the form of guess problem while test result of learning in the form of pretest and postest. Subjects in this study were 2nd semester students with 36 students. The result of survey documentation study during one semester shows that 2 semester students STKIP Bina Insan Mandiri still lack in critical thinking and innovative in following learning. This is because the giving strategy and teaching method belom maximally. Monotonous learning in the classroom becomes one of the factors of non-success in teaching and learning activities in the classroom. Thus in the course of education PKN SD fun learning materials will be given a game that can make students the spirit in following the learning in the classroom.
Implementasi Group Investigation Dengan Pendekatan Problem Based Learning untuk Meningkatkan Kemampuan Hasil Belajar Mahasiswa
Authors: Prastyaningtyas Efa Wahyu , Widiawati Hestin Sri
Published: July 2018

The learning approach used by a lecturer should be able to keep up with the times (innovative). Accounting system is a course that must be taken by students of economic education. Achievement of learning to be achieved in this course is students are able to analyze, compile and design the accounting system at the company. Based on the results of interviews and observations made during the learning process took place, obtained the results are still many students who do not pay attention to the explanation of the lecturer. This resulted in low learning outcomes, with 55% showing that 35 students did not meet the Minimum Exhaustiveness Criteria (KKM). In this study used approach to learning that refers to the approach of group investigation and problem-based learning with the aim of improving the ability of students to analyze and provide student solutions in the process of learning accounting system so as to improve learning outcomes. This study uses a classroom action research type. The data analysis of this research is descriptive quantitative. The result of the research shows that the approach of study which refers to group investigation and problem based learning approach can improve student learning outcomes from cycle 1 to cycle II in the problem orientation stage until the presentation of the final result.
Media Pembelajaran 5m Meretas Kendala Guru Dalam Membentuk Karakter Siswa ”Thumb Generation” Berakhlak Mulia
Authors: Tjasmadi Maria Patricia
Published: July 2018

The general discription that comes when hearing the words of Student Thumb Generation (STG) is;  technology literate student, high curiosity, multi-tasking, creative and innovative, and responsive to change. In addition to these positive things, there is a negative side that is quite apprehensive and will impact on everyday life and association. In general, STG tends to be selfish, narcissistic, and intolerant.If the above advantages can be combined with noble character, the competency standard of the graduates specified in the Regulation of the Minister of Education and Culture No. 54 of 2013 on the qualification of graduate ability that includes attitude, knowledge, and skills can be realized. Given the attitude dimension in accordance with the Minister Regulation above, the writer will explain about the utilization of 5M learning media that can motivate STG at elementary school education level to build behavior that reflect the attitude of the faithful, noble, knowledgeable, confident, and responsible in interacting effectively with the social and natural environment in the home, school, and playground. 5M learning media can be obtained easily and can be adapted to the depth of teaching materials, because in general the raw materials of this media can be obtained around the life of students. Through the empowerment of this media, STG can interact well so that noble character can be build.
Menumbuhkan Karakter Peserta Didik melalui Pendidikan Multikultural Pada Pembelajaran Seni Budaya
Authors: Pradana Rizal Wahyu Bagas
Published: July 2018

In this era of globalization, education art and culture have an important role in the formation of the character of students. Therefore, it needs a learning-based multicultural art and culture as solutions in tackling the problem in the characters of adult learners. This is important as part of an effort to prevent menangulangi and radicalism, separatism, ethnic conflict to religion, and in an effort to cultivate an attitude of heterogeneity, plurality, appreciate cultural diversity and love of the motherland. In the study of art and culture-based multicultural education there are three aspects in it, the third aspect of this is that later will be able to successful multicultural education. In the absence of these three aspects is very unlikely to achieve the multicultural learning, the third aspect is the aesthetics, appreciation, and humanization. The existence of these three aspects will make it easier to maximize the development of the realm kognititf, psychomotor, affective and student as solution character education through multicultural education.
Pengaruh Kompetensi Guru Shadow Terhadap Indikator Penilaian Pada Sekolah Inklusi MI Terpadu Ar-Roihan
Authors: Sari Melisa Wahyu Fandyan , Rahmah Tities Hijratur
Published: July 2018

This study aims to "know the effect of teacher shadow competence on indicator value ", formulation of the problem "how the effect of teacher shadow competence on indicator value ". Inclusion schools are public schools that combine regular students with ABK students. In general, teacher competence is divided into four, namely competence: 1) pedagogy, personality, social and professional. But for shadow teachers there are additional competencies that should be mastered that is performative competence. Requirements for teachers to master performative competence are to understand and understand the circumstances surrounding the environment, plan goals and strategies, transmit positive values to the environment, create message intelligence. The assessment of shadow teachers at MIT Ar-Roihan has the name of the indicator value, consisting of eight aspects of the assessment, namely: 1) making learning tools, 2) learning implementation, 3) learning evaluation, 4) reporting learning outcomes, 5) attitudes, 6) making media, 7) additional tasks, and 8) special achievements. This research is a correlational quantitative research, location at MIT Ar-Roihan Lawang, Malang Regency. The sample of the research used total sampling technique with 37 teachers. Data analysis using linear regression technique. From the results, obtained correlation coefficient value R = 0,596 and included medium category. From the table "ANOVA", obtained Regression value is 0.000 and <0,05 then concluded "There is a significant influence between teacher shadow competence (X) on indicator value (Y)".
Using Facebook Comments in Teaching Writing Skill
Authors: Ramadhani Pungky
Published: July 2018

In learning a language, writing is considered as the most difficult skill to be mastered by the students. They should pay attention on the writing components to produce a good writing. This becomes a challenge for the teachers. The teachers should create a new atmosphere of teaching writing. In this case, the existence of media is needed. Facebook was found to be the most popular social media site used by students. There a lot of features provided by Facebook. One of the features is Facebook comments. In this research, the researcher will use Facebook comments in Facebook group as the media to teach writing skill.
41AG9 and 41AG10: Ancestral Caddo Sites on Percella Creek in the Angelina River Basin in East Texas
Authors: Perttula Timothy
Published: July 2018

Both 41AG9 (ET-609) and 41AG10 (ET-610) were identified and recorded by Gus E. Arnold in late 1939-early 1940 under the auspices of the very successful WPA University of Texas archaeological survey of East Texas; they are only ca. 400 m apart. The sites are on elevated alluvial landforms in the Percella Creek valley; Percella Creek is an eastward-flowing tributary to the Angelina River, and joins the river about 3 km to the east of the sites (Figure 1).

During Arnold’s archaeological survey, he collected substantial numbers of ceramic vessel sherds from both sites, and the sites were in plowed fields with good surface visibility. 41AG9 was estimated to cover ca. 1.5 acres, and had midden deposits, as well as disturbed remnants of Caddo burial features. Midden deposits and remnants of possible disturbed Caddo burial features were also noted at 41AG10, and the core of the site covered a ca. 60 x 60 m area (ca. 0.9 acres).
Report on Magnetic Gradient Survey at Three Caddo Sites in East Texas
Authors: McKinnon Duncan
Published: July 2018

The use of magnetic gradient at Caddo sites located throughout the Caddo people’s ancestral lands within the current areas of east Texas, southwest Arkansas, northeast Louisiana, and eastern Oklahoma has been very successful in the elucidation and mapping of the distributional characteristics of buried cultural features. January 2016 surveys conducted at three Caddo sites in East Texas (41CE475, 41CE476, and 41CE477) add to this growing corpus of remote sensing spatial data. The survey work was conducted in order to assess the nature of sub-surface preservation in different environmental and historical contexts and map the distribution of geophysical anomalies attributed to Caddo occupations. The following article presents results and preliminary interpretations.
IMPACT OF BEDAQUILINE ON THE EFFICIENCY OF COMPREHENSIVE THERAPY OF RESPIRATORY TUBERCULOSIS
Authors: Kondakova M. N. , Khabirov V. V. , Zhemkov V. F. , Shpakovskaya L. R. , Daynovets A. V. , Elkin A. V.
Published: July 2018

The objective of the study:to evaluate the possibility to enhance the clinical efficiency of treatment of pulmonary tuberculosis patients by adding bedaquiline to the fifth chemotherapy regimen.

Subjects and methods. The presented results were obtained through dynamic follow-up and treatment of 68 respiratory tuberculosis patients, treated in St. Petersburg TB Dispensary from 2014 to 2016.

Results. The clinical improvement manifested through relief of intoxication symptoms, normalization of blood count, reduction of infiltrate changes and healing of destruction. In a number of cases, relief of intoxication symptoms with reduction of bacillary excretion massiveness, infiltration and cavity sizes allowed preparing patients for the next stage of treatment – surgery.
Beta momentum strategy after extreme market movements
Authors: Zhao Xin , Li Mingsheng , Liu Liuling
Published: July 2018

The authors adopt an event study method and empirically investigate the performance of a beta momentum strategy (long in past winners of small beta and short in past losers of large beta) after extreme market movements in 20 countries. The researchers find that the beta momentum strategy yields material abnormal returns after controlling for return factors of size (SMB), book-to-market (HML) and momentum (UMD). The results are consistent for both extreme market UP days or DOWN days and regardless of whether the extreme market movements are identified by three percent or two percent cut-off points. In addition, the results based on the beta momentum strategy are more consistent than those of conventional momentum and betting against beta (BAB) strategies over different test windows from (0, +1) days to (0, +90). Finally, the abnormal returns based on momentum, BAB, and our beta momentum strategies are statistically insignificant for the Asian and Australian subsamples, whereas the results are significant for the European and North American samples.
The prospects for using bemiparin in prophylaxis and treatment of thromboses in oncology
Authors: Somonova O. V. , Elizarova A. L. , Nesterova Yu. A. , Borisenko N. N. , Kornyushenko U. A.
Published: July 2018

Oncological patients have a high risk of thrombotic complications, which worsen the outcomes of antitumor treatment and is one of the leading causes of death. Low molecular weight heparins are the main drugs for the prevention and treatment of thrombotic complications in cancer patients. Zibor (bemiparin) is a second-generation low-molecular-weight heparin (LMWH) that has the lowest molecular weight (3600 Dalton), a half-life increased to 5.3 hours and the highest anti-Factor Xa activity ratio (8:1). In clinical trials, bemiparin has demonstrated high efficacy and safety for prophylaxis and treatment of thromboembolic complications.
The use of regorafenib in patients with disseminated gastrointestinal stromal tumours. A review of the literature. A clinical case
Authors: Filonenko D. A. , Petukhova S. V. , Khatkova E. I. , Vorontsova K. A. , Chichikov E. I. , Medvedeva B. M. , Zhukova L. G.
Published: July 2018

The survival of patients even with disseminated disease reached 7–8 years after introduction of imatinib and sunitinib for the treatment of gastrointestinal stromal tumours (GIST) into everyday clinical practice. These drugs efficacy is largely determined by the presence and any mutations of C-KIT and PDGFR genes. It was established that new mutations appear in most tumours against the background of tyrosine kinase inhibitors therapy, which causes the development of secondary resistance and the progression of the disease in most cases. The search for opportunities to overcome the newly developed or initially existing resistance caused by different gene mutations continues to be of vital importance. One of such drugs is regorafenib, which has demonstrated antitumour activity against progression on imatinib and/or sunitinib. The paper reviews the studies of the efficacy of regoraphanib in patients with disseminated GIST, taking into account the presence and any mutations of C-KIT and PDGFR genes, and presents a description of their own clinical case of prolonged use of the drug in a patient who have received earlier both imatinib and sunitinib.
Case report of the rapid achievement of sustained and long-term remission resulting from the use of ramucirumab plus paclitaxel in the second-line treatment of a patient with disseminated gastric adenocarcinoma
Authors: Titova T. A. , Besova N. S. , Gorbunova V. A. , Kuvshinov Yu. P. , Filatov A. A. , Ketsba A. F. , Fedenko A. A.
Published: July 2018

Ramucirumab is a monoclonal antibody targeting vascular endothelial growth factor receptor 2. In two randomised clinical trials Ramucirumab either alone or in combination with paclitaxel has been found to be safe and effective for patients with previously treated advanced gastric cancer. One of the serious adverse events associated with ramucirumab is bleeding.

We report the case of a 56-year-old man with advanced gastric cancer located at the gastroesophageal junction with liver, pulmonary and multiple lymph node metastases, plevritis was treated with a paclitaxel plus Ramucirumab regimen. We demonstrate a case of a cardioesophageal junction bleeding due to the high efficiency of treatment. He was successfully treated with by applying only hemostatical therapy, but after stop the bleeding chemotherapy was not reintroduced. The partial response was maintained for approximately 10 months. The patient died on 28 November 2017.

Chemotherapy with best supportive care for metastatic gastric cancer shown the improvement the performance status, help keep the cancer under control and help relieve symptoms during the time.
A new way of concentrating the cellular material of exudates
Authors: Leonov M. G. , Novik V. I. , Belyaeva S. A. , Ershova Ya. H.-B. , Selifonova Zh. P.
Published: July 2018

Objective. Improve the method for concentrating the cellular material of serous cavities exudates for cytological investigation.

Materials and methods. The optimal time of accumulation of cell samples in effusion liquids was determined on the basis of the sedimentation method using a dropping funnel by examining 28 samples of exudates (pleural and abdominal) obtained from 24 patients with ovarian cancer. The two methods for concentrating the cellular material of exudate were compared: the method using a dropping funnel and the method using a cylinder.

Results. It was found that the 60-minute exposure time was optimal in using a dropping funnel to concentrate the cellular material of exudates.

Conclusion. Using a dropping funnel to concentrate the cellular material of the exudates is optimal. In this case, the investigational preparations contain a sufficient amount of cellular material for the cytological study and the cell complexes are larger than those in using the cylinder.
Basal cell cancer treatment. Therapeutic experience with vismodegib therapy
Authors: Petenko N. N. , Demidov L. V.
Published: July 2018

Most patients with basal cell cancer (BCC) can be cured if timely diagnosed. However approximately 1,3% of BCCs may develop into locally-advanced and sometimes even metastatic disease when local treatment options are limited and systemic therapy is warranted. Vismodegib was the first drug which demonstrated efficacy for the treatment of locally-advanced and metastatic BCC, inhibiting pathologically active Sonic Hedgehog (SHh) signaling pathway in tumor cells and preventing their uncontrolled proliferation.
The prospects for cisplatin and nab-paclitaxel combination therapy in patients with pre-treated triple-negative breast cancer. Description of the clinical case.
Authors: Zhukova L. G. , Bardovskaya K. S. , Lubennikova E. V. , Suslova I. R.
Published: July 2018

Molecular and biological features of triple negative breast cancer (TN BC) determine the limited possibilities of systemic therapy and, as a consequence, the more aggressive course of the disease. Taxanes are one of the most effective chemotherapies used in breast cancer therapy. The special form of paclitaxel nab-paclitaxel makes it possible to obtain an objective and a subjective effect, which is especially important in the pre-treated patients. In addition, the drug has a favourable safety profile and a well-controlled toxicity.

The article contains a review of the literature on the prospects for the use of nab-paclitaxel in breast cancer, especially in its triple negative version, and a description of the clinical case of therapy with a combination of cisplatin and nab-paclitaxel in a young patient with BRCA-1-associated TN breastcancer.
Radium-223 for the treatment of patients with castration-resistant prostate cancer with bone metastases
Authors: Kaprin A. D. , Kostin A. A. , Vorobyev N. V. , Popov S. V.
Published: July 2018

The development of resistance to endocrine therapy and the tumor progression in patients with prostate cancer are associated with an unfavourable prognosis. The article presents a review of clinical trials of efficacy and safety, as well as the experience in using radioisotope radium-223 chloride in clinical practice in patients with castration-resistant prostate cancer with bone metastases without visceral metastases. It was shown that radium-223 chloride therapy in this category of patients leads to an increase in overall survival and time to the development of bone complications, and is characterized by good tolerability.
A Walk in Nature: Sesquiterpene Lactones as Multi-Target Agents Involved in Inflammatory Pathways
Authors: Coricello Adriana , Adams James D. , Lien Eric J. , Nguyen Christopher , Perri Filomena , Williams Travis J. , Aiello Francesca
Published: July 2018

Inflammatory states are among the most common and most treated medical conditions.
Inflammation comes along with swelling, pain and uneasiness in using the affected
area. Inflammation is not always a simple symptom; more often is part of a defensive response
of the body to an external threat or is a sign that the damaged tissue has not healed yet
and needs to rest. The management of the pain associated with an inflammatory state could be
a tricky task. In fact, most remedies simply quench the pain, leaving the inflammatory state
unaltered. This review focuses on sesquiterpene lactones, a class of natural compounds, that
represents a future promise in the treatment of inflammation. Sesquiterpene lactones are efficient
inhibitors of multiple targets of the inflammatory process. Their natural sources are often
ancient remedies with relevant traditional uses in folk medicines. This work also aims to
elucidate how these compounds may represent the starting material for the development of
new anti-inflammatory drugs.
Potent Chitin Synthase Inhibitors from Plants
Authors: Vijayakumar Amrutha , Madhavan Ajith , Bose Chinchu , Nanjan Pandurangan , Kokkal Sindhu S. , Veedu Archana P. , Prasad Megha , Pal Sanjay , Nair Bipin G.
Published: July 2018

Background:

Chitin is the main component of fungal, protozoan and helminth cell wall. They help to maintain the structural and functional characteristics of these organisms. The chitin wall is dynamic and is repaired, rearranged and synthesized as the cells develop. Active synthesis can be noticed during cytokinesis, laying of primary septum, maintenance of lateral cell wall integrity and hyphal tip growth. Chitin synthesis involves coordinated action of two enzymes namely, chitin synthase (that lays new cell wall) and chitinase (that removes the older ones). Since chitin synthase is conserved in different eukaryotic microorganisms that can be a ‘soft target’ for inhibition with small molecules. When chitin synthase is inhibited, it leads to the loss of viability of cells owing to the self- disruption of the cell wall by existing chitinase.

Methods:

In the described study, small molecules from plant sources were screened for their ability to interfere with hyphal tip growth, by employing Hyphal Tip Burst assay (HTB). Aspergillus niger was used as the model organism. The specific role of these small molecules in interfering with chitin synthesis was established with an in-vitro method. The enzyme required was isolated from Aspergillus niger and its activity was deduced through a novel method involving non-radioactively labelled substrate. The activity of the potential lead molecules were also checked against Candida albicans and Caenorhabditis elegans. The latter was adopted as a surrogate for the pathogenic helminths as it shares similarity with regard to cell wall structure and biochemistry. Moreover, it is widely studied and the methodologies are well established.

Results:

Out of the 11 compounds and extracts screened, 8 were found to be prospective. They were also found to be effective against Candida albicans and Caenorhabditis elegans.

Conclusion:

Purified Methyl Ethyl Ketone (MEK) Fraction1 (F1) of Coconut (Cocos nucifera) Shell Extract (COSE) was found to be more effective against Candida albicans with an IC50 value of 3.04 μg/mL and on L4 stage of Caenorhabditis elegans with an IC50 of 77.8 μg/mL.
Predictive Factors for Successful High Myopia Treatment Using High-Frequency Laser-In-Situ Keratomileusis
Authors: Artini Widya , B. Riyanto Setyo , Hutauruk Johan A. , D. Gondhowiardjo Tjahjono , Kekalih Aria
Published: July 2018

Aim:

To evaluate the predictive factors of LASIK procedure for high myopia with or without astigmatism using a combination of high-frequency femtosecond-assisted LASIK followed by an excimer laser.

Methods:

This study was a retrospective interventional case series study to evaluate myopic eyes undergoing high platform LASIK with FEMTO LDV Z2 intervention, followed by WaveLight®EX500 excimer laser machine. Subjects were divided into 2 groups: high myopia (SE of -6.01 to -9.00 D) and very high myopia (SE of -9.01 D or higher). Myopic eyes (Spherical Equivalent/SE) less than –13 D were included in this study. Visual Acuity (VA) was evaluated 1 day and 60 days after the procedure. Predictive factors, such as age, degree of sphere, degree of astigmatism, keratometric reading and axial length were analyzed to detect any influences affecting the final VA results.

Results:

A total of 316 myopia eyes underwent intervention, mean age: 25.3±3.8 years. Target treatment was achieved in 96.1% of patients with high myopia and 69.9% of patients with very high myopia. High degree of sphere and astigmatism constitutes an important factor influencing final VA.

Conclusion:

Modern machines provide a more promising efficacy and success of LASIK procedure in high myopia: important predictive factors were a high degree of sphere and astigmatism for achieving the optimal final outcome.
The Use of Psychoactive Substances and Illegal Drugs in the Albanian Society
Authors: Matua Linda , Muharremi Guido , Petrela Elizana , Koçibelli Mirnela , Vyshka Gentian , Xhemali Bledar
Published: July 2018

Background:

To create a representative picture of the prevalence and the total number of
drug users in Albania from 2012 to 2016, and compare those numbers to previous years with other
available data.

Methods:

The required data for the conductance of this study was collected from three different
fronts, namely The Institute of Forensic Medicine (IFM), Clinical Toxicology and Addictions Service,
University Hospital "Mother Theresa" Tirana (CTS) and Methadone Maintenance Treatment
Centers. The study targets all individuals who have consumed at least once abusive drugs and psychotropic
substances during the period 2012-2016 in the Republic of Albania. A total of 7050 reported
cases over the given period were reviewed.

Results:

Overall, Cannabis Sativa was the highest consumed drug, present in 62.58% of the cases.
Other substances with a noticeable prevalence of use were heroin (15.02%) and cocaine (5.1%). It
was found out that there were 36 drug-related deaths from 2012 to 2016. During this period of time,
only 9 individuals resulted positive for Sexually Transmitted Infections (STI), of which, one positive
for Hepatitis C and the remaining 8 positives for HIV. About 25% of drug users in Albania belong
to the young subgroup of the population (13-32 years old).

Conclusion:

Overall, taking into consideration all three databases, the number of drug users has significantly
increased. There are more officially reported drug users today compared to 2012,
however, different trends are observed during different periods. Youngsters are more eager and
tempted to use and experiment more with safer and less harmful drugs like cannabis, meanwhile, as
age increases, there is a tendency to shift towards more potent and dangerous drugs. Prevention and
reducing the prevalence of use of psychoactive drugs is one of the main goals of public health.