bluuebunny/crossref_metadata_2025 huggingface dataset:
Proposta de implementação da sala de leitura: visando o desenvolvimento para a formação de cidadãos críticos
Authors: Lima Lysne Nôzenir de
Published: January 2018

Este trabalho é um recorte de um Projeto de uma Sala de Leitura que tem como objetivo a implementação da sala de leitura em uma escola pública de ensino fundamental do Estado de Roraima localizada na periferia de Boa Vista, por meio de um professor capacitado que deverá realizar atividades de leitura com estratégia para desenvolver a criatividade, o pensamento lógico, incentivo, interesse e hábito daleitura pelos educandos, em parceria com todos os professores, oportunizando assimo fortalecimento e integração no processo de ensino aprendizagem.
Educação, consciência de classe e estratégia revolucionária
Authors: Iasi Mauro
Published: January 2018

Baseado na exposição realizada na mesa de mesmo nome no V EBEM (Encontro Brasileiro deEducação e Marxismo) em abril de 2011, na Universidade Federal de Santa Catarina (UFSC). Publicado pela primeira vez na Revista Universidade e Sociedade, n 48, ano XXI, julho de 2011, ANDES, p. 122-130.
Uso de moedas de centavos de Real em uma discussão sobre densidade e empuxo
Authors: Souza Thalita Ferreira Menegassi de , Ribeiro Anderson Orzari
Published: January 2018

Qual a importância da densidade em nosso cotidiano? E o empuxo? Muitos alunos já se fizeram estas e outras perguntas, principalmente quando estes conceitos são apresentados sem qualquer relação com a realidade cotidiana. Neste artigo apresentamos uma possibilidade de trabalho interdisciplinar com os temas acima a partir de um experimento simples que possibilita a medida da relação entre a massa e o volume de diferentes moedas do Real, dinheiro oficial do Brasil. A proposta aqui discutida foi realizada com um grupo de alunos de um curso preparatório popular da cidade de Ribeirão Preto (SP), o CIMEAC – Conexão, e pode ser reproduzida por educadores em qualquer ambiente escolar do Brasil, sem a necessidade de uso de um laboratório de ciências. A partir da determinação da densidade do material, determinados pela análise gráfica dos dados obtidos, pode-se introduzir em sala de aula uma discussão sobre os conceitos teóricos e as aplicações práticas da Densidade e do Empuxo, mostrando ao aluno sua importância na produção e utilização de materiais e artefatos presentes em seu dia a dia.
Os cursos pré-vestibulares populares enquanto espaços educativos e de formação docente: algumas reflexões
Authors: Verrangia Douglas
Published: January 2018

O presente texto traz uma reflexão pautada na literatura e na experiência de trabalho em Cursinhos Pré-Vestibulares Populares, cursos preparatórios orientados a pessoas das camadas empobrecidas de nossa população. Trata-se de um relato de experiência e, ao mesmo tempo, ensaio teórico/prático no qual argumento no sentido de ampliar a compreensão, sobre o que entendo por relativo sucesso dos Cursos Pré-Vestibulares Populares (CPVP) em duas questões: enquanto espaço educativo para jovens e adultos de camadas empobrecidas da população; e enquanto espaço de formação inicial de professores(as). Como pano de fundo, procuro olhar para o que temdado certo nos espaços educativos criados pelos cursinhos populares, a fim de compreender falhas e apontar caminhos para a melhoria da educação formal pública, de onde vêm os sujeitos que, na busca por implementar seus projetos de vida, chegam a esses espaços de educação popular.
Temas, conceitos e processos em educação popular: uma discussão a partir das ciências sociais
Authors: Narita Felipe Ziotti
Published: January 2018

Este artigo discute proposições e possibilidades de entendimento da educação popular a partir de formulações teóricas do campo das ciências sociais. Trata-se de situar a discussão da educação popular no conjunto mais amplo de problemas lançados pelas ciências sociais, analisando as práticas educativas à luz de processos sociopolíticos, sobretudo, a partir de referenciais sociológicos e históricos (democratização política, cidadania, modernização). Por meio da exposição e da discussão de alguns dos conceitos e abordagens que vinculam a educação popular a temas mais amplos das ciências sociais, o texto argumenta que o entendimento da educação popular, para além das discussões curriculares e de conteúdo, deve ser teoricamente inserido na investigação dos próprios impasses sociais, políticos e econômicos que acompanham a América Latina nas últimas cinco décadas.
Effect of heat stress for specific period on juvenile traits, feed efficiency and some heat stress parameters in different genetic groups of broilers
Authors: Reddy B. L.N. , Rajaravindra K. S. , Rajkumar U. , Reddy M. R.
Published: January 2018

To evaluate the effect of heat stress an experiment was conducted in which one cross (PB-1X Naked neck), two pure lines ( PB-1 and Naked neck) and corresponding control populations were generated simultaneously on the same day.120 chicks in PB-1X Naked neck (Control 120), 91 chicks in Naked neck pure( Control 82) and 81 chicks in PB-1 pure ( Control 80)were generated. Temperatures were raised (up to 40°C) by providing the two halogen lamps in each of the heat stressed genetic groups from 4-6 weeks of age. Body weights were recorded at 0, 2,4, 6 and 7 weeks of age along with conformational traits like breast angle and shank length at 6 weeks of age. 2ml of blood was collected at 6weeks of age from all the 6 genetic groups (10 birds from each) to estimate the heat stress parameters. Feed efficiency was recorded at 6 weeks and 7 weeks of age. Significant differences were found for SOD, CAT, ALP and GPx between heat stressed and control genetic groups. Higher estimates were found in heat stressed genetic groups as compared to corresponding control groups. For juvenile body weights in stressful conditions there is significant difference between genetic groups. Lower juvenile body weights were recorded in heat stressed genetic groups as compared to control groups. Lower feed efficiency was recorded in heat stressed genetic groups as compared to corresponding control groups.
Genetic characterization of local goats of Karnataka by microsatellite marker analysis
Authors: Jayashree R. , Jayashankar M. R. , Nagaraja C. S. , Shrikrishna Isloor , Satyanarayana K.
Published: January 2018

The diversity status of local goats of Karnataka was studied by using microsatellite marker analysis. The genomic DNA from unrelated local goats were PCR- amplified with a panel of 23 microsatellite markers. Microsatellite PCR products were multiplexed and run on capillary based genetic analyser and the raw data obtained was analysed. Totally 158 alleles were observed and the number of alleles ranged from three (ILSTS005 and OarJMP29) to 13 (RM088). The number of effective alleles ranged from 2.25 (ILSTS005) to 8.40 (RM088) in all the 23 loci studied. The mean observed heterozygosity (Ho) was 0.4698±0.2214 [range 0 (ETH225) to 0.8462 (ILSTS034)] and the mean expected heterozygosity (He) was 0.7471± 0.1098 [range 0.5656 (ILSTS005) to 0.9138 (SRCRSP 8)] indicating the heterogenous nature of the local goat population of Karnataka.
Simultaneous selection model based evaluation of arsenic tolerance in black gram (Vigna mungo L.) using morphological parameters
Authors: Shamim M. Z. , Pandey Anjana
Published: January 2018

The evaluation of black gram under arsenic stress is important to identify the arsenic-tolerant genotypes for cultivation in arsenic affected soil and for crop improvement programs. Thirty-two black gram genotypes were received from Indian Institute of Pulses Research (IIPR) Kanpur, India was grown in sand and exposed to three arsenic toxicity levels (control, 150 and 300 µM NaAsO2). Root length, root weight, shoot length, shoot weight and total biomass of plants were recorded in the vegetative stage.The plants were grown in pots (45×30×20 cm)following CRD during Kharif 2014 and experiment was performed in three replications.The morphological characters of almost all genotypes were significantly decreased with increased concentration of arsenic in supplied nutrients, shoot length; root length was less affected, whereas shoot weight, root weight and total biomass were much decreased under arsenic stress condition. Selection of genotypes according to simultaneous selection index model suggests that genotypes IPU 99-176, IPU 25, IPU 2K 99-224 and IPU 99-3 are much successfully able to tolerate arsenic toxicity. The arsenic tolerance capacity of UH 82-14 and UPU 8335 were decreased with increasing concentration of NaAsO2 as compared to other genotypes. The genotypes IPU 99-235, UPU 8335, UH 82-14, LBG 623 and IPU 99-115 has very less capacity to cope arsenic toxicity. The genotypes IPU 99-176 and IPU 25 are appropriate for cultivation in arsenic affected soil as well as these genotypes may be much useful for hybridization program to develop the arsenic-tolerant heterotic cultivars. The root biomass and shoot biomass should be improved to develop arsenic tolerance in black gram. The ranking of genotypes based on multiple morphological parameters has great advantage on conventional methods under abiotic stress.
Studies on integrated Agro-Techniques approaches for yield maximization of pigeonpea [Cajanus Cajan (L.) Millsp.] in Mid-Hills of Tripura, India
Authors: De Biman , Ray Subrata , Das Partha , Hazari Sujoy
Published: January 2018

Pigeonpea is cultivated as a major source of protein for poor farmers with reduced yields. The low yield of pigeonpea is due to faulty agro techniques. The present investigation was conducted to see the effect of integrated agro-techniques on growth and growth attributes of pigeonpea and designed with block randomization having eight treatments viz., integrated nutrient management (INM), integrated weed management (IWM), integrated pest management (IPM) and its combos at AICRP experimental farm, College of Agriculture Tripura. Growth and yield attributes differed significantly due to integrated agro-techniques with poor weed population in IWM. The net come was highest in INM+IWM+IPM (Rs. 49243.85 and Rs. 47757.63). Results revealed that INM+IWM+IPM yielded higher followed by INM+IWM however each of them was statistically at par throughout the study. Economics led INM+IWM as best treatment than the combination of 3 agro-techniques, where additional price occurred.
RESISTENCIA AL CORTE DE MUROS DE HORMIGON ARMADO
Authors: Leyva L. Gilberto , Montaño Juan Carlos
Published: January 2018

Se analiza una serie de datos experimentales disponibles en la literatura sobre resistencia al corte de muros de hormigón armado, estudiándose el efecto de los principales parámetros que afectan esta resistencia. Utilizando el modelo que considera por separado las contribuciones Vs del refuerzo transversal y Vc del hormigón, se detectaron dos importantes efectos. En primer lugar, se determinó que el aporte Vs del refuerzo transversal alcanza solamente al 70% del valor establecido en la norma de diseño del ACI. En segundo lugar, se detectó claramente el efecto de degradación de la contribución del hormigón Vc, causada por la demanda de deformaciones no lineales y el consecuente daño asociado. A partir del estudio analítico del mecanismo de transferencia de corte a través de la cabeza de compresión del muro, y del análisis de los resultados experimentales, se ha desarrollado un modelo de resistencia al corte que incluye los efectos antes mencionados. Dados los datos experimentales disponibles, la demanda de deformaciones no lineales en flexión fue evaluada mediante la ductilidad de curvatura alcanzada al instante de la falla. La expresión obtenida mantiene la forma tradicional, incorporando el efecto de la demanda de ductilidad y del nivel de solicitación en flexión sobre la componente Vc.
MODELLING THE CYCLIC RESPONSE OF RC BEAM-COLUMN MEMBERS
Authors: Miramontes de León Diego , Merabet Omar , Reynouard Jean
Published: January 2018

La mayoría de los modelos cíclicos uniaxiales formulados en variables globales (M, φ) toman en cuenta varios fenómenos esenciales de las secciones de Concreto Reforzado. Sin embargo, a menudo se asumen descargas elásticas lineales. Esta suposición involucra una disipación nula deenergía para cargas cíclicas no alternantes, mientras que los resultados observados muestran degradación de resistencia y disipación de energía. Más aun, para cargas cíclicas alternantes como las sísmicas, la disipación de energía observada está relacionada con el comportamiento no lineal tanto en carga como en descarga. La falta de atención a este comportamiento producedeformaciones residuales más pequeñas y, en consecuencia, un comportamiento histerético diferente. Con el propósito de lograr una predicción más realista, se incluye un comportamiento de descarga bilineal a una ley cíclica. El trabajo está basado en un modelo previamente implementado en el programa de uso general CASTEM2000 del Comisariado Francés para la Energía Atómica (CEA). El modelo se caracteriza por una curva envolvente trilineal y un conjunto de reglas cíclicas.La pérdida de rigidez y la degradación de resistencia tanto en la rama scendente como en la descendete y el amortiguamiento histerético dependen directamente del nivel e historia de carga aplicada. Las ecuaciones de movimiento se resuelven por el método de Newmark centrado y las condiciones de borde se imponen por medio de los multiplicadores de Lagrange. En este trabajo sedescribe la estrategia de análisis no lineal usando los multiplicadores de Langrange y el modelo cíclico propuesto. Los resultados numéricos se han comparado en experimentos con varios miembros estructurales y sub-ensambles sujetos a diferentes condiciones de carga. La comparación muestra el interés del modelo modificado propuesto.
OBSERVACIONES SOBRE ALGUNOS CRITERIOS DE DISEÑO SÍSMICO DE EDIFICIOS CON MARCOS DE CONCRETO REFORZADO
Authors: Luna Arroyo Jose L , Tena Colunga Arturo
Published: January 2018

Se presenta un análisis de las disposiciones de las Normas Técnicas Complementarias para Diseño y Construcción de Estructuras de Concreto (NTCC-96) del Reglamento de construcciones para el Distrito Federal (RCDF-93) basado en una comparación con diferentes reglamentos internacionales, dicha comparación se enfoca en las disposiciones para marcos dúctiles y marcos no dúctiles contemplando las diferencias desde el punto de vista conceptual, numérico e intuitivo. Se toma como base de la comparación el reglamento del ACI 318-95, ya que la mayoría de los códigos se apoyan en sus especificaciones y se analizan los reglamentos resaltando las diferencias existentes con el código base. Se presentan las diferencias más relevantes entre los reglamentos internacionales y el RCDF-93. Las formulaciones y criterios exclusivos de las NTCC-96 parecen no estar apoyados suficientemente en investigaciones analíticas o experimentales. Se hace patente que algunas de ellas, pueden llegar a complicar y a hacer tedioso el proceso de diseño injustificadamente. Se comentan algunas modificaciones a las NTCC-96 que se incluyen en la Propuesta de las Normas Técnicas Complementarias para Diseño y Construcción de Estructuras de Concreto (NTCC-2001) actualmente en evaluación
RESPUESTA ACOPLADA DE TRASLACIÓN Y TORSIÓN DE ESTRUCTURAS ASIMÉTRICAS INCLUYENDO LA INTERACCIÓN CON EL SUELO
Authors: Suarez Martha , Avilés Javier
Published: January 2018

Considerando los efectos de interacción suelo-estructura, se estudia la respuesta acoplada de traslación y torsión de estructuras asimétricas desplantadas sobre un estrato de suelo ante excitación sísmica. El sistema investigado consiste en un oscilador simple torsionalmente acoplado con cimentación enterrada en un estrato blando sobre un semiespacio elástico, sometido a ondas SH condiferentes ángulos de incidencia. Se calculan soluciones numéricas para varias configuraciones del sistema, tomando como movimiento de control el gran temblor de Michoacán de 1985 registrado en tres sitios representativos de las zonas blanda y de transición en el Valle de México. Se evalúan la amplificación dinámica de la excentricidad y la relación entre las fuerzas cortantes acopladas y desacopladas, y se comparan con las actuales recomendaciones reglamentarias para estructuras de edificios (Normas Técnicas Complementarias para Diseño por Sismo del RCDF, Gaceta Oficial Del Distrito Federal, 1995). Se muestra que, al menos para comportamiento lineal de la estructura, lasespecificaciones de diseño por torsión pueden subestimar la máxima respuesta estructural cuando los efectos de interacción son de excepcional importancia, como sucede en la Ciudad de México.
MODELO DE UN GRADO DE LIBERTAD PARA EVALUAR LA CURVA CARGA LATERAL-DISTORSIÓN EN MUROS DE MAMPOSTERÍA CONFINADA
Authors: Sánchez Tizapa Sulpicio , Arroyo Matus Roberto , Jerez Sandra
Published: January 2018

Este artículo presenta un modelo simple para evaluar la curva de carga lateral-distorsión en ensayes de muros de mampostería confinada. El modelo propone sustituir la mampostería por un elemento resorte, cuyas propiedades mecánicas son obtenidas mediante pruebas en paneles de mamposteríasujetos a tensión diagonal. De esta manera, un muro de mampostería (integrado por castillos y mampostería) es modelado como un sistema equivalente de un grado de libertad con desplazamiento lateral, cuya respuesta es obtenida mediante un análisis estático no lineal, considerando exclusivamente deformaciones de cortante. La comparación con resultadosexperimentales obtenidos en México para muros y sistemas estructurales ensayados bajo carga cíclica lateral muestran la capacidad del modelo, que tiene aproximación aceptable hasta una distorsión igual a 0.45 % para muros elaborados con tabique rojo recocido y 0.35 % para muros elaborados con piezas de concreto. Ambos valores son mayores que el permisible definido en elReglamento del Distrito Federal. Adicionalmente, los resultados tienen una aproximación similar a la obtenida en modelos complejos de elemento finito, columna ancha y puntales de compresión
CONTROL DE ACELERACIONES DE ENTREPISO PARA SISTEMAS ESTRUCTURALES CON AISLAMIENTO SÍSMICO DE BASE
Authors: Zúñiga Cuevas Oscar , Terán Gilmore Amador
Published: January 2018

Se evalúa la respuesta sísmica de una serie de sistemas simples con aislamiento sísmico de base para entender el efecto que las propiedades estructurales de dichos sistemas y de su super-estructura tienen en las demandas de aceleración de entrepiso. Se supuso que los sistemas estructuralespermanecen elásticos y que la disipación de energía en el sistema de aislamiento puede modelarse como amortiguamiento viscoso. La diferencia entre los niveles de amortiguamiento de la superestructura y el sistema de aislamiento fue tomada en cuenta a través de un enfoque de amortiguamiento no-clásico. Para la evaluación de la respuesta dinámica de los sistemas seutilizaron movimientos del terreno registrados en sitios de suelo firme ubicados en la costa del Pacífico Mexicano. Una vez identificadas las propiedades estructurales que permiten el control de las demandas de aceleración de entrepiso, se discute el uso de un sistema equivalente de un grado de libertad para el diseño de sistemas estructurales de no más de cuatro niveles con aislamiento sísmico de base
INFLUENCIA DE CONTRAVENTEOS CONCÉNTRICOS EN CRUZ O CHEVRÓN EN EL COMPORTAMIENTO NO LINEAL DE MARCOS DÚCTILES DE CONCRETO REFORZADO
Authors: Godínez Domínguez Eber Alberto
Published: January 2018

Se presenta un estudio en que se evalúa, mediante análisis estáticos no lineales, la influencia de dos esquemas de contraventeo en el comportamiento estructural de marcos dúctiles de concreto reforzado, así como su impacto en algunos parámetros de diseño. Los marcos diseñados se encuentran en el intervalo de los cuatro a 20 niveles, contando con contraventeo metálico tipo chevrón y en cruz. De los resultados obtenidos, es posible concluir, que existe dependencia de los factores de reducción por sobrerresistencia (R) con el esquema de contraventeo considerado, por tal razón, se proponen expresiones para el cálculo de los factores R para cada caso. Asimismo, se propone un valor de distorsión para la revisión del estado límite de servicio independiente del esquema de contraventeo. Se muestra que la distorsión propuesta en las NTCS-04 para la revisión del estado límite de prevención de colapso es adecuada para ambos esquemas de contraventeo. También, se propone una expresión para la determinación del aporte mínimo de las columnas al cortante resistente del sistema ante carga lateral como función de la relación de esbeltez de la estructura, aplicable a las dos configuraciones de contraventeo estudiadas. Finalmente, del conjunto de resultados, se concluye que para los modelos de cuatro a 16 niveles, para ambas configuraciones de contraventeo, es posible obtener diseños con capacidades de deformación adecuadas que cumplan con un mecanismo de colapso cercano al esperado de columna fuerte-viga débil-contraviento más débil si se emplea la metodología de diseño por capacidad propuesta y las columnas aportan al menos el 50% del cortante resistente de entrepiso.Palabras Clave: marcos dúctiles contraventeados; contraventeo chevrón; contraventeo en cruz; marcos de concreto reforzado; diseño por capacidad; análisis estáticos no lineales
MODELACIÓN NO LINEAL DE MUROS DE MAMPOSTERÍA EMPLEANDO ELEMENTOS DE CONTACTO
Authors: Lizárraga José , Pérez Gavilán Juan José
Published: January 2018

Se presenta la modelación de muros de mampostería simple y confinada sometidos a carga axial y lateral con el método de los elementos finitos para obtener la envolvente de resistencia a corte. Se utilizan elementos de contacto en las juntas para tomar en cuenta el comportamiento no lineal en la mampostería. Se tomaron en cuenta los dos tipos de falla más comunes: la falla en tensión (Modo I) y la falla a cortante (Modo II); en ambos casos se consideró el ablandamiento. En el rango elástico, se corroboró la consistencia de los resultados obtenidos con el modelo de elementos de contacto con los producidos con un modelo detallado y un modelo homogeneizado. En el rango no lineal, se utilizó un modelo trilineal de la superficie de fluencia que no incluye una reducción de la resistencia por el esfuerzo normal, a diferencia del esquema propuesto por otros autores que si la toman en cuenta. El efecto de esta consideración se estudió mediante la comparación de los resultados obtenidos con el modelo propuesto y los resultados numéricos y experimentales reportados en la literatura. Se comentan las principales diferencias. Finalmente, se modela un muro confinado ensayado en el laboratorio para comparar la envolvente de resistencia a corte experimental con la obtenida numéricamente. Los resultados obtenidos son bastante similares.
Mesa Directiva
Authors: AC SOCIEDAD MEXICANA DE INGENIERÍA
Published: January 2018

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ESTUDIO DE PELIGRO SÍSMICO DE ECUADOR Y PROPUESTA DE ESPECTROS DE DISEÑO PARA LA CIUDAD DE CUENCA
Authors: Quinde Martínez Pablo David , Reinoso Angulo Eduardo
Published: January 2018

En este trabajo se presenta un estudio de peligro sísmico para el Ecuador. La falta de catálogos sísmicos completos, o en muchos casos la poca información relacionada al tema, hace que sea necesario un análisis probabilista de amenaza sísmica de manera que sea posible considerar las diferentes incertidumbres que se presentan en el proceso de cálculo. Esta metodología ha sido empleada en el presente trabajo para el estudio de peligro sísmico del Ecuador. Se debe partir de un catálogo que sea lo suficientemente depurado, homogéneo y completo, de manera que los parámetros sísmicos de las diferentes fuentes no presenten grandes desviaciones en sus resultados. Posteriormente, se estudiaron diferentes modelos de atenuación, los mismos que son necesarios para conocer las intensidades en cualquier punto de interés. En este estudio se obtienen resultados de peligro sísmico como curvas de peligro, espectros de peligro uniforme (EPU) y mapas de peligro sísmico, para diferentes periodos de retorno. Como aplicación de estos resultados, se obtienen espectros de diseño sísmico para la ciudad de Cuenca, partiendo de un estudio previo de efectos de sitio realizado por la Universidad de Cuenca en el año 2000.Palabras clave: peligro sísmico; catálogo sísmico; espectros de peligro uniforme; curvas de peligro símico; espectros de diseño; efectos de sitio
DETERMINACIÓN DE ESPECTROS DE RESPUESTA CONSIDERANDO DAÑO ACUMULADO E INTERACCIÓN SUELO-ESTRUCTURA
Authors: Rodríguez Castellanos Ali Abraham , Bojórquez Mora Edén , Reyes Salazar Alfredo , Avilés López Javier , Ruiz Gómez Sonia E.
Published: January 2018

En este trabajo se evaluó en primer lugar la ductilidad cíclica en sistemas de un grado de libertad con comportamiento no lineal que representan estructuras sismo-resistentes considerando el efecto de las demandas acumuladas de deformación plástica e interacción suelo-estructura (ISE). Adicionalmente, se trazaron espectros de respuesta de ductilidad máxima y cíclica constante considerando ISE. Para alcanzar los objetivos del presente estudio, varios sistemas simplificados se sometieron a movimientos sísmicos registrados en sitios de suelo blando de la Ciudad de México, donde se ha observado efecto importante de ISE y daño acumulado. Se demostró que las demandas acumuladas de deformación plástica pueden tener influencia considerable en el comportamiento sísmico reduciendo la capacidad de ductilidad de las edificaciones, y por otro lado incrementando las ordenadas espectrales de manera importante. Finalmente, el impacto de la ISE depende principalmente de la flexibilidad del suelo, y puede tener efectos benéficos tanto como perjudiciales dependiendo de la razón entre el periodo del sistema y del suelo, incrementando o reduciendo la respuesta de una estructura.
Musicalidade cênica ou cenicidade musical
Authors: Silva Carlos Alberto
Published: January 2018

Musicalidade cênica, ou cenicidade musical, como aqui apresentada, se referencia nas relações entre parâmetros acústicos e os demais componentes sintáticos da linguagem da encenação, a partir dos fundamentos da Rítmica, das proposições da vanguarda artística e dos primeiros encenadores do século XX. A proposição converge para a percepção da vocalidade no eixo da articulação de que música é movimento e movimento é música.
Prevalence of Mental Disorders and Addictions among the Homeless Population in the Greater Paris Area, France
Authors: Laporte Anne , Vandentorren Stéphanie , Détrez Marc-Antoine , Douay Caroline , Le Strat Yann , Le Mener Erwan , Chauvin Pierre
Published: January 2018

The Samenta study was conducted in 2009 in the Greater Paris area to estimate the prevalence of psychiatric disorders among the homeless. A cross-sectional survey was performed with a three-stage random sample of homeless people (n = 859), including users of day services, emergency shelters, hot meal distribution, long-term rehabilitation centres and social hotels. Information was collected by a lay interviewer, using the Mini International Neuropsychiatric Interview, and completed by a psychologist through an open clinical interview. In the end, a psychiatrist assessed the psychiatric diagnosis according to the ICD10. One third of the homeless in the Paris area had at least one severe psychiatric disorder: psychotic disorders (13%), anxiety disorders (12%) or severe mood disorders (7%). One in five was alcohol dependent and 18% were drug users. Homeless women had significantly higher prevalence of anxiety disorders and depression and men were more likely to suffer from psychotic disorders. Homeless people of French origin were at higher risk of SPD, as well as people who experienced various adverse life events before the age of 18 (running away, sexual violence, parental disputes, and/or addictions) and those who experienced homelessness for the first time before the age of 26. The prevalence rates of main psychiatric disorders within the homeless population of our study are consistent with those reported in other Western cities. Our results advocate for an improvement in detection, housing and care of psychiatric homeless.
Aligning Strategy with Sustainable Development Goals (SDGs): Process Scoping Diagram for Entrepreneurial Higher Education Institutions (HEIs)
Authors: Fleaca Elena , Fleaca Bogdan , Maiduc Sanda
Published: January 2018

The sustainable development of our world has gain particular attention of a wide range of decisional factors, civil society, business sector, and scientific community, seeing that the prosperity of people and society is possible with the aid of sustained and inclusive economic growth of all countries and regions. Educational environment has a decisive impact on changes in the way that societies are coping with national, regional, and global challenges and opportunities brought by sustainable development. Looking at the implications of HE on the progress of society, the paper addressed the lack of HE institutional capacity to integrate the principles and practices of sustainable development into all aspects of education and learning. The scope of research problem was bounded on the capability of HEI as organization and school to act as entrepreneurial university by combining the scope of its responsibility within the value chain through a practical and effective mechanism needed to align the strategy with sustainable development goals (SDGs). Embarking on the path of SDGs requires HEI to design, launch, implement, and customize specific processes architectures to govern the advance of sustainability approach. The authors applied the process scoping diagram to capture and conceptualize the educational model needed to guide the HEI through the process of change to embrace sustainability into organizational culture and daily operations. It has been used the SIPOC method (Supplier, Input, Process, Output, Customer) with Visio software tool to articulate processes relationships embedded in the educational model of HEI. The benefits relied on the organized view of the work processes needed to be performed to incorporate SDGs into the strategy of any entrepreneurial HEI. Finally, the authors shared their views on the scalability of the model which may be customized and harmonized in accordance with different HE circumstances and priorities. Implementing the proposed educational model requires long-term institutional commitment, transparency, continuous performance improvement, and communicating the strategy for SDGs and its achievements to wider stakeholders.
A Significance of MMP-1 in EGFR-TKI Resistant Lung Adenocarcinoma: A Potential of Therapeutic Target
Authors: Saito Ryoko , Miki Yasuhiro , Ishida Naoya , Inoue Chihiro , Kobayashi Masayuki , Hata Shuko , Yamada-Okabe Hisafumi , Okada Yoshinori , Sasano Hironobu
Published: January 2018

Lung adenocarcinoma with EGFR-TKI (epidermal growth factor receptor-tyrosine kinase inhibitor) resistance was reported to harbor higher ability of invasion and migration than those sensitive to EGFR-TKI, but the function of MMPs (matrix metalloproteinases) has not been explored in EGFR-TKI resistant lung adenocarcinoma. In this study, the correlation between immunohistochemical status of MMP-1 and clinicopathological factors were analyzed in 89 lung adenocarcinoma. We performed microarray, migration assay and invasion assay using EGFR-TKI sensitive cell lines and EGFR-TKI resistant cell lines. To clarify the mechanism of MMP-1 induction, we treated lung adenocarcinoma cells with EGF and rapamycin, performed phosphorylation antibody array and analyzed the correlation between MMP-1 expression and EGFR or mTOR (mammalian target of rapamycin) pathway. As a result, we firstly demonstrated that MMP-1 played an important role in migration and invasion abilities of EGFR-TKI resistant lung adenocarcinoma, and that mTOR pathway could be associated with an induction of MMP-1. We demonstrated the significant positive correlation between MMP-1 status in lung adenocarcinoma cells and the history of smoking, and the subtype of invasive mucinous adenocarcinoma. In conclusion, This study provides insights into the development of a possible alternative therapy manipulating MMP-1 and mTOR signaling pathway in EGFR-TKI resistant lung adenocarcinoma.
EDUCAÇÃO A DISTÂNCIA, TIC E FORMAÇÃO DE PROFESSORES DE PEDAGOGIA: UM ESTUDO DE CASO A PARTIR DA MÍDIA-EDUCAÇÃO
Authors: Sousa Galdino Rodrigues de , Borges Eliane Medeiros
Published: January 2018

O texto é um recorte de uma dissertação de mestrado que investiga a educação e as Tecnologias de Informação e Comunicação (TIC) nos documentos curriculares (PPC, Plano de Ensino, Matriz Curricular) do curso de Pedagogia a distância da Universidade Federal de Juiz de Fora (UFJF). Para isso, os dados foram coletados e organizados a partir da mídia-educação e de suas respectivas dimensões. A metodologia envolveu: i) pesquisa no site institucional do curso; ii) análise de conteúdo dos documentos estruturantes e dos componentes curriculares que tematizavam as TIC; iii) contato com os responsáveis institucionais pelo curso com o intuito de coletar mais informações referentes aos documentos estruturantes e suas possíveis relações com as TIC. A pesquisa mostrou que o curso de formação de professores estudado faz referências e prevê a educação para as TIC em seus documentos curriculares, principalmente por meio da oferta obrigatória de componentes curriculares, sobretudo nas dimensões Instrumental-operativa e Objeto de Estudo da mídia-educação.
DIÁLOGOS NA EDUCAÇÃO PÚBLICA POR MEIO DO RAP E DO JAZZ
Authors: Ferreira Tiago Lazzarin
Published: January 2018

O objetivo deste artigo é o de apresentar reflexões desenvolvidas a partir de uma pesquisa sobre a formação cultural (Bildung) e o engajamento estético de estudantes do ensino médio. As ideias de formação e de engajamento se basearam nas concepções filosóficas de Theodor Adorno e Vilém Flusser respectivamente. Essas reflexões teóricas subsidiaram a análise de campo de atividades educativas que envolveram a audição musical, debates sobre a avaliação estética de composições de rap e de jazz e a participação em práticas coletivas de improvisação. Com isso, pretendeu-se analisar aspectos formativos que emergiram do diálogo entre um professor de Sociologia com formação em Música e estudioso de jazz e estudantes que, em grande parte, são ouvintes de rap e engajados na cultura hip-hop, moradores das imediações do bairro de Heliópolis, na cidade de São Paulo.
Length-weight relationships and condition factor of Hyperopisus bebe (Lacepede, 1803) (Actinopterygii: Osteoglossiformes) in River Galma, Zaria, Kaduna State, Nigeria
Authors: Moise Matouke M.
Published: January 2018

The investigation of length-weight relationship and condition factor are very relevant indices to ascertain the health of fish in the water body. Length-weigh relationship and condition factor of Hyperopisus bebe (Lacepede, 1803) (Actinopterygii: Osteoglossiformes: Mormyridae) in River Galma, Zaria, Kaduna State, Nigeria, were assessed. The mean length and mean weigh in male and female were 26.703 cm +/- 0.51 cm and 25.32 cm +/- 0.898 cm; 158.2 g +/- 10.1 g and 95.91 g +/- 9.26 g, respectively. The exponent or growth pattern 'b' values for male and female were 2.009 and 2.176. The condition factor for male and female were 0.59 and 0.83, respectively. The negative allometric growth pattern and poor condition factor might be due to the poor water quality in the fish ecosystem and should be regarded with concern.
Recent Advances in the Development of Antimicrobial Peptides (AMPs): Attempts for Sustainable Medicine?
Authors: Kokel Anne , Torok Marianna
Published: January 2018

Background:

Since the first isolation of antimicrobial peptides (AMPs) they
have attracted extensive interest in medicinal chemistry. However, only a few AMP-based
drugs are currently available on the market. Despite their effectiveness, biodegradability,
and versatile mode of action that is less likely to induce resistance compared to conventional
antibiotics, AMPs suffer from major issues that need to be addressed to broaden
their use. Notably, AMPs can lack selectivity leading to side effects and cytotoxicity, and
also exhibit in vivo instability. Several strategies are being actively considered to overcome
the limitations that restrain the success of AMPs.

Methods:

In the current work, recent strategies reported for improving AMPs in the context
of drug design and delivery were surveyed, and also their possible impact on patients
and the environment was assessed.

Results:

As a major advantage AMPs possess an easily tunable skeleton offering opportunities
to improve their properties. Strategic structural modifications and the beneficial
properties of cyclic or branched AMPs in term of stability have been reported. The conjugation
of AMPs with nanoparticles has also been explored to increase their in vivo stability.
Other techniques such as the coupling of AMPs with specific antibodies aim to increase
the selectivity of the potential drug towards the target. These strategies were evaluated
for their effect on the environment highlighting green technologies.

Conclusion:

Although further research is needed taking into account both environmental
and human health consequences of novel AMPs, several of these compounds are promising
drug candidates for use in sustainable medicine.
The Role of Oestrogen Receptor Beta (ERβ) in the Aetiology and Treatment of Type 2 Diabetes Mellitus
Authors: Ofosu Wendy Amy , Mohamed Dahir , Corcoran Olivia , Ojo Opeolu Oyejide
Published: January 2018

Introduction:

Challenges facing the treatment of type 2 diabetes necessitate the search for agents which act via alternative pathways to provide better therapeutic outcomes. Recently, an increasing body of evidence implicates the activation of oestrogen receptors (ERα and ERβ) in the development and treatment of underlying conditions in type 2 diabetes. This article summarizes available evidence for the involvement of oestrogen receptors in insulin secretion, insulin resistance as well as glucose uptake and highlights the potential of ERβ as a therapeutic target.

Background:

Recent studies indicate an association between the activation of each of the isoforms of ER and recent findings indicate that ERβ shows promise as a potential target for antidiabetic drugs. In vitro and in vivo studies in receptor knockout mice indicate beneficial actions of selective agonists of ERβ receptor and underscore its therapeutic potential.

Conclusion:

Studies are needed to further elucidate the exact mechanism underlying the role of ERβ activation as a therapeutic approach in the management of type 2 diabetes.
Evaluation of a Gravity Flow Membrane Bioreactor for Treating Municipal Wastewater
Authors: Platten William E. , Campo Pablo , Suidan Makram T. , Venosa Albert D.
Published: January 2018

The biomass concentrator reactor (BCR), a gravity flow membrane bioreactor (MBR) design, was evaluated for use in treating a municipal wastewater stream. The BCR operates with less than 2.5 cm of pressure head and uses a 3 to 4 mm thick tortuous path membrane with pore size ranging from 18 to 28 μm to achieve solids separation. A two‐stage, aerobic/anoxic reactor was evaluated for the removal of chemical oxygen demand (COD), ammonia, total nitrogen, and solids separation. The reactor was fed 72 L/day, with a hydraulic retention time of 9.3 hours, and had a solids retention time of 20 days. The influent COD was reduced by 93%, whereas, influent ammonia was reduced below 0.1 mg/L and total nitrogen was reduced by 53.7%. A lack of readily biodegradable COD limited denitrification and thus total nitrogen removal. The reactor solids were retained completely in the reactor by the membrane for the duration of testing.
Understanding Cyber Time

Due to the vast number of high-profile cyber-attacks in 2017, cyber threats are now deeply present within the psyche of all industries and within our private lives. The response has been explosive, fueling rapid increases in technology spending, calls for increased regulation, in cyber workforce expansion and in insurance and risk management strategies. For any of these responses to be effective the math, specifically the impact and realities of time, must be studied very carefully. With hundreds of new attacks launched each minute, traditional technology management approaches are proving inadequate due to the simple fact that they cannot keep up with the pace of the adversaries. Cyber threats can be viewed (Preprint)
Authors: Perakslis Eric
Published: January 2018

BACKGROUND

There is an old expression in agriculture that the best time to plant a tree was 20 years ago. The second best time, is today. This is exactly where we find ourselves today with healthcare cyber security. The systems we use simply were not designed or built, nor are they currently managed, for the types of advanced persistent threats that face us. There are many ways that cyber security and cyber resilience can be approached and optimized but the most significant factor is time.
The majority of systems supporting critical healthcare missions were developed over the course of years, or even decades. Major revisions and new features are developed over the course of months and years. Fixes and updates are typically delivered monthly or as daily emergency releases. System operators extend the time to achieve these system improvements with testing and validation of systems, updates, and patches to ensure functionality and that no unintended consequences are being introduced. This extended lifecycle leaves critical missions lacking functionality and exposed to cyber risks on a continual basis. It is impossible for most organizations to stay up to speed with cyber defense.

OBJECTIVE

To relay the importance of building cyber strategies that understand and optimize the essential nature of cyber time.

METHODS

NA. Viewpoint piece

RESULTS

NA - viewpoint Piece

CONCLUSIONS

Cybersecurity varies greatly from most domains of risk management in that there is always a determined adversary actively executing an agenda that inevitably brings harm to targeted organizations. This adversary is moving at unprecedented speed and organizations must build and execute strategies that enable response and resiliency in real-time to meet this unprecedented level of persistent threat.
Clinical Cybersecurity Training Through Novel High Fidelity Simulations (Preprint)
Authors: Dameff Christian , Selzer Jordan , Fisher Jonathan , Killeen James , Tully Jeffrey
Published: January 2018

BACKGROUND

Cybersecurity risks in healthcare systems have traditionally been measured in data breaches of protected health information but compromised medical devices and critical medical infrastructure raises questions about the risks of disrupted patient care. The increasing prevalence of these connected medical devices and systems implies that these risks are growing.

OBJECTIVE

This paper details the development and execution of three novel high fidelity clinical simulations designed to teach clinicians to recognize, treat, and prevent patient harm from vulnerable medical devices.

METHODS

Clinical simulations were developed which incorporated patient care scenarios with hacked medical devices based on previously researched security vulnerabilities.

RESULTS

Clinician participants universally failed to recognize the etiology of their patient’s pathology as being the result of a compromised device.

CONCLUSIONS

Simulation can be a useful tool in educating clinicians in this new, critically important patient safety space.
Mid-gestational exposure to histone deacetylase inhibitor suberoylanilide hydroxamic acid influence cortical interneuron and astrocyte in mouse brain
Authors: Yuniarti Nunung , Juliandi Berry , Sanosaka Tsukasa , Nakashima Kinichi
Published: January 2018

Suberoylanilide hydroxamic acid (SAHA) has been reported preclinically to diffuse across the placenta and to be found in fetal plasma, suggesting that it can influence the fetus if taken by a pregnant cancer patient. In utero exposure of SAHA to mouse embryos during mid-gestation was found to perturb corticogenesis. However, the influence of in utero administration of SAHA to mouse embryos during mid-gestation on astrocyte, glial cell, and inhibitory neurons (interneurons) is yet to be reported. Pregnant dams were divided into control and SAHA groups and given methyl cellulose (as control) and SAHA orally once a day for 3 days during mid-gestation, starting from embryonic day (E)12 until E14. Astrocyte, interneuron, and behavior analyses were performed on the pups from postnatal day 7 until adulthood (3 months old). Brains were harvested and immunohistochemistry, Western Blot, and RT-PCR were performed on their cortex area. Transient exposure of SAHA to mouse embryos resulted in a decrease and increase in cortical astrocyte and interneuron, respectively. Meanwhile, adult SAHA mice displayed significantly increased anxiety, decreased memory, altered long-term cognitive functions, and reduced social interactions. Our study suggests that exposure to SAHA during prominent neurogenic periods might imbalance the normal excitatory:inhibitory neuron ratio required for the precise regulation of physiological functions in the brain.
Expression of haloacid dehalogenase gene and its molecular protein characterization from Klebsiella pneumoniae ITB1
Authors: Anggoro Ridani Rino , Ratnaningsih Enny
Published: January 2018

Organohalogen compounds are widely used industrially and agriculturally, as well as in households as flame retardants and refrigerants. However, these compounds can become significant pollutants through their accidental or deliberate release into the environment in large quantities. Dehalogenase is an enzyme with the potential to be used in the removal of organohalogen contaminants. A previous study successfully subcloned a 690 bp of haloacid dehalogenase gene (hakp1) from Klebsiella pneumoniae ITB1 into a pET-30a(+) expression system to achieve high enzyme productivity. IPTG was used as an inducer to express a pET-hakp1 recombinant clone in Escherichia coli BL21 (DE3). The molecular mass of the haloacid dehalogenase Hakp1 protein was 30 kDa as determined by SDS-PAGE. Zymogram analysis showed that this recombinant protein has dehalogenase activity as shown by the formation of AgCl white precipitate. A quantitative assay of haloacid dehalogenase Hakp1 gave a specific activity of 84.29 U/mg with the optimum temperature of 40°C at pH 9. Predicted three-dimensional structure of Hakp1 showed α/β motif folding which comprised of cap and core domain. The predicted active sites of Hakp1 were Asp8, Glu10, Leu22, Phe23, Trp90, Ser125, Ser126, Lys159, and Asp184 with Asp8, Glu10, Ser126, and Lys159 act as binding residue. This recombinant haloacid dehalogenase clone provides an alternative agent for effective bioremediation of organohalogen pollutants.