bluuebunny/crossref_metadata_2025 huggingface dataset:
Hydrodynamics of Direct Contact Condensation Process in Desuperheater
Authors: Ghazwani Hassan A. , Khan Afrasyab , Taranenko Pavel Alexanrovich , Sinitsin Vladimir Vladimirovich , Ghazwani Mofareh H. H. , Alnujaie Ali H. , Sanaullah Khairuddin , Ullah Atta , Rigit Andrew R. H.
Published: September 2022

Due to global environmental conditions, the focus of household heating has shifted from fossil fuels towards environmentally friendly and renewable energy sources. Desuperheaters have attracted attention as a domestic provision involving steam-induced direct contact condensation (DCC)to warm the water. The present study is an attempt to investigate the hydrodynamics in the desuperheater vessel experimentally, namely, when the pressurized pulsating steam is injected into the vessel, where the steam jet interacts co-currently with the slow-moving water. Flow visualization showed a circulation region when the pulsating steam was injected into the slow-moving water, and the peaked vorticity corresponded to the steam injection duration of 10–60 s. Sevenhot film anemometers (HFAs) were traversed axially and radially to determine the velocity fluctuations at 0–20 cm from the steam’s nozzle exit. Vortical structures indicated the entrainment of the steam with the surrounding moving water. The circulation regions were thus exhibited in relation to the steam’s injection durations as well as the downstream axial distances of 2 and 15 cm from the nozzle exit, which showed that the core local circulation at 2 cm downstream of the nozzle exit lost 75–79% of its circulation at 15 cm downstream of the nozzle exit.
An Insight into the Impacts of Memory, Selling Price and Displayed Stock on a Retailer’s Decision in an Inventory Management Problem
Authors: Rahaman Mostafijur , Abdulaal Reda M. S. , Bafail Omer A. , Das Manojit , Alam Shariful , Mondal Sankar Prasad
Published: September 2022

The present paper aims to demonstrate the combined impact of memory, selling price, and exhibited stock on a retailer’s decision to maximizing the profit. Exhibited stock endorses demand and low selling prices are also helpful for creating demand. The proposed mathematical model considers demand as a linear function of selling price and displayed inventory. This work utilized fractional calculus to design a memory-based decision-making environment. Following the analytical theory, an algorithm was designed, and by using the Mathematica software, we produced the numerical optimization results. Firstly, the work shows that memory negatively influences the retailer’s goal of maximum profit, which is the most important consequence of the numerical result. Secondly, raising the selling price will maximize the profit though the selling price, and demand will be negatively correlated. Finally, compared to the selling price, the influence of the visible stock is slightly lessened. The theoretical and numerical results ultimately imply that there can be no shortage and memory restrictions, leading to the highest average profit. The recommended approach may be used in retailing scenarios for small start-up businesses when a warehouse is required for continuous supply, but a showroom is not a top concern.
Existence of Mild Solutions for Hilfer Fractional Neutral Integro-Differential Inclusions via Almost Sectorial Operators
Authors: Varun Bose Chandra Bose Sindhu , Udhayakumar Ramalingam
Published: September 2022

This manuscript focuses on the existence of a mild solution Hilfer fractional neutral integro-differential inclusion with almost sectorial operator. By applying the facts related to fractional calculus, semigroup, and Martelli’s fixed point theorem, we prove the primary results. In addition, the application is provided to demonstrate how the major results might be applied.
Fullerenol C60(OH)36 Protects the Antioxidant Enzymes in Human Erythrocytes against Oxidative Damage Induced by High-Energy Electrons
Authors: Grebowski Jacek , Kazmierska-Grebowska Paulina , Cichon Natalia , Konarska Anna , Wolszczak Marian , Litwinienko Grzegorz
Published: September 2022

Ionizing radiation (IR) can pass through the human body easily, potentially causing severe damage to all biocomponents, which is associated with increasing oxidative stress. IR is employed in radiotherapy; however, in order to increase safety, it is necessary to minimize side effects through the use of radioprotectors. Water-soluble derivatives of fullerene exhibit antiradical and antioxidant properties, and these compounds are regarded as potential candidates for radioprotectors. We examined the ability of fullerenol C60(OH)36 to protect human erythrocytes, including the protection of the erythrocytal antioxidant system against high-energy electrons. Human erythrocytes irradiated with high-energy [6 MeV] electrons were treated with C60(OH)36 (150 µg/mL), incubated and haemolyzed. The radioprotective properties of fullerenol were determined by examining the antioxidant enzymes activity in the hemolysate, the concentration of -SH groups, as well as by determining erythrocyte microviscosity. The irradiation of erythrocytes (650 and 1300 Gy) reduces the number of thiol groups; however, an attenuation of this harmful effect is observed (p < 0.05) in the presence of C60(OH)36. Although no significant effect of fullerenol was recorded on catalase activity, which was preserved in both control and test samples, a more active protection of other enzymes was evident. An irradiation-induced decrease in the activity of glutathione peroxidase and glutathione reductase became an increase in the activity of those two enzymes in samples irradiated in the presence of C60(OH)36 (p < 0.05 and p < 0.05, respectively). The fourth studied enzyme, glutathione transferase, decreased (p < 0.05) its activity in the irradiated hemolysate treated with C60(OH)36, thus, indicating a lower level of ROS in the system. However, the interaction of fullerenol with the active centre of the enzyme cannot be excluded. We also noticed that radiation caused a dose-dependent decrease in the erythrocyte microviscosity, and the presence of C60(OH)36 reduced this effect (p < 0.05). Overall, we point to the radioprotective effect of C60(OH)36 manifested as the protection of the antioxidant enzymes of human erythrocytes against IR-induced damage, which has not been the subject of intense research so far.
Cardiac Toxicity Associated with Immune Checkpoint Inhibitors: A Systematic Review
Authors: Cozma Angela , Sporis Nicolae Dan , Lazar Andrada Luciana , Buruiana Andrei , Ganea Andreea Maria , Malinescu Toma Vlad , Berechet Bianca Mihaela , Fodor Adriana , Sitar-Taut Adela Viviana , Vlad Vasile Calin , Negrean Vasile , Orasan Olga Hilda
Published: September 2022

Immune checkpoint inhibitors (ICIs) are an important advancement in the field of cancer treatment, significantly improving the survival of patients with a series of advanced malignancies, like melanoma, non-small cell lung cancer (NSCLC), hepatocellular carcinoma (HCC), renal cell carcinoma (RCC), and Hodgkin lymphoma. ICIs act upon T lymphocytes and antigen-presenting cells, targeting programmed cell death protein 1 (PD1), programmed cell death protein ligand 1 (PD-L1), and cytotoxic T-lymphocyte antigen 4 (CTLA-4), breaking the immune tolerance of the T cells against malignant cells and enhancing the body’s own immune response. A variety of cardiac-adverse effects are associated with ICI-based treatment, including pericarditis, arrhythmias, cardiomyopathy, and acute coronary syndrome, with myocarditis being the most studied due to its often-unexpected onset and severity. Overall, Myocarditis is rare but presents an immune-related adverse event (irAE) that has a high fatality rate. Considering the rising number of oncological patients treated with ICIs and the severity of their potential adverse effects, a good understanding and continuous investigation of cardiac irAEs is of the utmost importance. This systematic review aimed to revise recent publications (between 2016–2022) on ICI-induced cardiac toxicities and highlight the therapeutical approach and evolution in the selected cases.
Copper(II) Etioporphyrinate as a Promising Photoluminescent and Electroluminescent Temperature Sensor
Authors: Chernyadyev Andrey Yu. , Aleksandrov Alexey E. , Lypenko Dmitry A. , Tsivadze Aslan Yu.
Published: September 2022

Luminescent temperature sensors are of great interest because they allow remote determination of temperature in transparent media, such as living tissues, as well as on scattering or transparent surfaces of materials. This study analyzes the luminescent properties of copper(II) etioporphyrinate (Cu-EtioP) in a polystyrene film upon variation of temperature from −195 °C to +65 °C in a cryostat. It is shown that the ratio of intensities of phosphorescence transitions in the red spectral region of such a material varies significantly, that is, the material has thermosensory properties. The phosphorescence decay curves of copper(II) etioporphyrinate in a polystyrene film are analyzed. The quantum yield of phosphorescence of copper(II) etioporphyrinate determined by the absolute method was 3.15%. It was also found that the electroluminescence (EL) spectra of copper(II) etioporphyrinate in a poly(9-vinylcarbazole) (PVK) matrix demonstrated a similar change in the spectra in the temperature range −3 °C to +80 °C. That is, copper(II) etioporphyrinate can also be used as a luminescent temperature sensor as part of an active OLED layer.
Spontaneous Transformation of Biomedical Polymeric Silver Salt into a Nanocomposite: Physical–Chemical and Antimicrobial Properties Dramatically Depend on the Initial Preparation State
Authors: Abzaeva Klavdia A. , Sukhov Boris G. , Khutsishvili Spartak S. , Tarabukina Elena B. , Zelenkov Lev E. , Nevezhina Anna V. , Fadeeva Tat’yana V.
Published: September 2022

An antimicrobial polyacrylic silver salt (freshly prepared, stored for one year and model-aged) was studied by physical–chemical techniques for nanoparticle detection. In all cases, this salt represents a composite of radical-enriched macromolecules and silver(0) nanoparticles. As time passed, the initial small spherical nanoparticles were converted into larger non-spherical silver nanoparticles. The initial highly water-soluble antimicrobial solid nanocomposite almost loses its solubility in water and cannot be used as an antimicrobial agent. Unlike insoluble solid silver polyacrylate, its freshly prepared aqueous solution retains a liquid-phase consistency after one year as well as pronounced antimicrobial properties. The mechanism of these spontaneous and model-simulated processes was proposed. These results have attracted attention for officinal biomedicinal silver salts as complex radical-enriched nanocomposite substances; they also indicate contrasting effects of silver polymeric salt storing in solid and solution forms that dramatically influence antimicrobial activity.
The Efficacy and Biopharmaceutical Properties of a Fixed-Dose Combination of Disulfiram and Benzyl Benzoate
Authors: Lajarin-Reinares Maria , Martinez-Esteve Elia , Pena-Rodríguez Eloy , Cañellas-Santos Mariona , Bulut Sanja , Karabelas Kostas , Clauss Adam , Nieto Carles , Mallandrich Mireia , Fernandez-Campos Francisco
Published: September 2022

Scabies and hair lice are parasitic diseases that affect human skin and hair, respectively. The incidence and resistances of these infections are increasing. Tenutex® (disulfiram and benzyl benzoate emulsion) is an alternative to standard insecticides to avoid resistances. The aim of the work is to evaluate the transdermal absorption and the in vitro efficacy against scabies and hair lice after different exposition times. Dermatomed human skin was used to assess the dermal absorption using a validated High Performance Liquid Chromatography (HPLC) method. HEK001 keratinocytes were used to evaluate the cytotoxicity of benzyl benzoate. Only benzyl benzoate was able to cross the skin, but it did not show cytotoxicity at any of the tested concentrations. The product efficacy was tested on Psoroptes ovis after direct contact and after administration on sheep skin explants at different contact times. Permethrin/malathion-resistant strains of Pediculus humanis capitis adults and eggs were directly exposed to Tenutex, and the vitality and hatchability, respectively, were evaluated. The anti-scabies study demonstrated that exposure for 6 or 24 h completely eradicated the parasite. The pediculicidal activity of Tenutex exhibited superior efficacy than standard treatment on resistant lice. The positive results obtained suggest that Tenutex® is a good treatment option, especially in drug resistance situations.
Dosage Compensation in Drosophila: Its Canonical and Non-Canonical Mechanisms
Authors: Shevelyov Yuri Y. , Ulianov Sergey V. , Gelfand Mikhail S. , Belyakin Stepan N. , Razin Sergey V.
Published: September 2022

Dosage compensation equalizes gene expression in a single male X chromosome with that in the pairs of autosomes and female X chromosomes. In the fruit fly Drosophila, canonical dosage compensation is implemented by the male-specific lethal (MSL) complex functioning in all male somatic cells. This complex contains acetyl transferase males absent on the first (MOF), which performs H4K16 hyperacetylation specifically in the male X chromosome, thus facilitating transcription of the X-linked genes. However, accumulating evidence points to an existence of additional, non-canonical dosage compensation mechanisms operating in somatic and germline cells. In this review, we discuss current advances in the understanding of both canonical and non-canonical mechanisms of dosage compensation in Drosophila.
Ultrasonic-Assisted Synthesis of Benzofuran Appended Oxadiazole Molecules as Tyrosinase Inhibitors: Mechanistic Approach through Enzyme Inhibition, Molecular Docking, Chemoinformatics, ADMET and Drug-Likeness Studies
Authors: Irfan Ali , Zahoor Ameer Fawad , Kamal Shagufta , Hassan Mubashir , Kloczkowski Andrzej
Published: September 2022

Furan-oxadiazole structural hybrids belong to the most promising and biologically active classes of oxygen and nitrogen containing five member heterocycles which have expanded therapeutic scope and potential in the fields of pharmacology, medicinal chemistry and pharmaceutics. A novel series 5a–j of benzofuran-oxadiazole molecules incorporating S-alkylated amide linkage have been synthesized using ultrasonic irradiation and screened for bacterial tyrosinase inhibition activity. Most of the synthesized furan-oxadiazole structural motifs exhibited significant tyrosinase inhibition activity in the micromolar range, with one of the derivatives being more potent than the standard drug ascorbic acid. Among the tested compounds, the scaffold 5a displayed more tyrosinase inhibition efficacy IC50 (11 ± 0.25 μM) than the ascorbic acid IC50 (11.5 ± 0.1 μM). Compounds 5b, 5c and 5d efficiently inhibited bacterial tyrosinase with IC50 values in the range of 12.4 ± 0.0–15.5 ± 0.0 μM. The 2-fluorophenylacetamide containing furan-oxadiazole compound 5a may be considered as a potential lead for tyrosinase inhibition with lesser side effects as a skin whitening and malignant melanoma anticancer agent.
Bile Salt Hydrolases with Extended Substrate Specificity Confer a High Level of Resistance to Bile Toxicity on Atopobiaceae Bacteria
Authors: Morinaga Kana , Kusada Hiroyuki , Tamaki Hideyuki
Published: September 2022

The bile resistance of intestinal bacteria is among the key factors responsible for their successful colonization of and survival in the mammalian gastrointestinal tract. In this study, we demonstrated that lactate-producing Atopobiaceae bacteria (Leptogranulimonas caecicola TOC12T and Granulimonas faecalis OPF53T) isolated from mouse intestine showed high resistance to mammalian bile extracts, due to significant bile salt hydrolase (BSH) activity. We further succeeded in isolating BSH proteins (designated LcBSH and GfBSH) from L. caecicola TOC12T and G. faecalis OPF53T, respectively, and characterized their enzymatic features. Interestingly, recombinant LcBSH and GfBSH proteins exhibited BSH activity against 12 conjugated bile salts, indicating that LcBSH and GfBSH have much broader substrate specificity than the previously identified BSHs from lactic acid bacteria, which are generally known to hydrolyze six bile salt isomers. Phylogenetic analysis showed that LcBSH and GfBSH had no affinities with any known BSH subgroup and constituted a new BSH subgroup in the phylogeny. In summary, we discovered functional BSHs with broad substrate specificity from Atopobiaceae bacteria and demonstrated that these BSH enzymes confer bile resistance to L. caecicola TOC12T and G. faecalis OPF53T.
Investigation of TLR2 and TLR4 Polymorphisms and Sepsis Susceptibility: Computational and Experimental Approaches
Authors: Behairy Mohammed Y. , Abdelrahman Ali A. , Toraih Eman A. , Ibrahim Emad El-Deen A. , Azab Marwa M. , Sayed Anwar A. , Hashem Hany R.
Published: September 2022

Toll-like receptors (TLR) play an eminent role in the regulation of immune responses to invading pathogens during sepsis. TLR genetic variants might influence individual susceptibility to developing sepsis. The current study aimed to investigate the association of genetic polymorphisms of the TLR2 and TLR4 with the risk of developing sepsis with both a pilot study and in silico tools. Different in silico tools were used to predict the impact of our SNPs on protein structure, stability, and function. Furthermore, in our prospective study, all patients matching the inclusion criteria in the intensive care units (ICU) were included and followed up, and DNA samples were genotyped using real-time polymerase chain reaction (RT-PCR) technology. There was a significant association between TLR2 Arg753Gln polymorphisms and sepsis under the over-dominant model (p = 0.043). In contrast, we did not find a significant difference with the TLR4 Asp299Gly polymorphism with sepsis. However, there was a significant association between TLR4 Asp299Gly polymorphisms and Acinetobacter baumannii infection which is quite a virulent organism in ICU (p = 0.001) and post-surgical cohorts (p = 0.033). Our results conclude that the TLR2 genotype may be a risk factor for sepsis in adult patients.
Effect of the Synthesis Conditions of MIL-100(Fe) on Its Catalytic Properties and Stability under Reaction Conditions
Authors: Delgado-Marín José J. , Narciso Javier , Ramos-Fernández Enrique V.
Published: September 2022

MIL-100(Fe) is a metal–organic framework (MOF) characterized by the presence of Lewis acid and Fe(II/III) redox sites. In this work, different synthesis methods for the preparation of MIL-100(Fe) are studied. Depending on the source of fluorine, different phases can be obtained: MIL-100(Fe) and an Fe trimesate with unknown structure which we call Fe(BTC). These materials were characterized using numerous techniques and applied in the reaction of CO2 cycloaddition with epichlorohydrin, a reaction catalyzed by Lewis acid sites. It was observed that samples with more Fe(BTC) phase were more active in the reaction. However, all samples, under reaction conditions, transformed into a less active phase.
A Tunable Hyperspectral Imager for Detection and Quantification of Marine Biofouling on Coated Surfaces
Authors: Santos Joaquim , Pedersen Morten Lysdahlgaard , Ulusoy Burak , Weinell Claus Erik , Pedersen Henrik Chresten , Petersen Paul Michael , Dam-Johansen Kim , Pedersen Christian
Published: September 2022

Fouling control coatings (FCCs) are used to prevent the accumulation of marine biofouling on, e.g., ship hulls, which causes increased fuel consumption and the global spread of non-indigenous species. The standards for performance evaluations of FCCs rely on visual inspections, which induce a degree of subjectivity. The use of RGB images for objective evaluations has already received interest from several authors, but the limited acquired information restricts detailed analyses class-wise. This study demonstrates that hyperspectral imaging (HSI) expands the specificity of biofouling assessments of FCCs by capturing distinguishing spectral features. We developed a staring-type hyperspectral imager using a liquid crystal tunable filter as the wavelength selective element. A novel light-emitting diode illumination system with high and uniform irradiance was designed to compensate for the low-filter transmittance. A spectral library was created from reflectance-calibrated optical signatures of representative biofouling species and coated panels. We trained a neural network on the annotated library to assign a class to each pixel. The model was evaluated on an artificially generated target, and global accuracy of 95% was estimated. The classifier was tested on coated panels (exposed at the CoaST Maritime Test Centre) with visible intergrown biofouling. The segmentation results were used to determine the coverage percentage per class. Although a detailed taxonomic description might be complex due to spectral similarities among groups, these results demonstrate the feasibility of HSI for repeatable and quantifiable biofouling detection on coated surfaces.
Blind Quality Prediction for View Synthesis Based on Heterogeneous Distortion Perception
Authors: Shi Haozhi , Wang Lanmei , Wang Guibao
Published: September 2022

The quality of synthesized images directly affects the practical application of virtual view synthesis technology, which typically uses a depth-image-based rendering (DIBR) algorithm to generate a new viewpoint based on texture and depth images. Current view synthesis quality metrics commonly evaluate the quality of DIBR-synthesized images, where the DIBR process is computationally expensive and time-consuming. In addition, the existing view synthesis quality metrics cannot achieve robustness due to the shallow hand-crafted features. To avoid the complicated DIBR process and learn more efficient features, this paper presents a blind quality prediction model for view synthesis based on HEterogeneous DIstortion Perception, dubbed HEDIP, which predicts the image quality of view synthesis from texture and depth images. Specifically, the texture and depth images are first fused based on discrete cosine transform to simulate the distortion of view synthesis images, and then the spatial and gradient domain features are extracted in a Two-Channel Convolutional Neural Network (TCCNN). Finally, a fully connected layer maps the extracted features to a quality score. Notably, the ground-truth score of the source image cannot effectively represent the labels of each image patch during training due to the presence of local distortions in view synthesis image. So, we design a Heterogeneous Distortion Perception (HDP) module to provide effective training labels for each image patch. Experiments show that with the help of the HDP module, the proposed model can effectively predict the quality of view synthesis. Experimental results demonstrate the effectiveness of the proposed model.
A Prediction Model of Defecation Based on BP Neural Network and Bowel Sound Signal Features
Authors: Zhang Tie , Huang Zequan , Zou Yanbiao , Zhao Jun , Ke Yuwei
Published: September 2022

(1) Background: Incontinence and its complications pose great difficulties in the care of the disabled. Currently, invasive incontinence monitoring methods are too invasive, expensive, and bulky to be widely used. Compared with previous methods, bowel sound monitoring is the most commonly used non-invasive monitoring method for intestinal diseases and may even provide clinical support for doctors. (2) Methods: This paper proposes a method based on the features of bowel sound signals, which uses a BP classification neural network to predict bowel defecation and realizes a non-invasive collection of physiological signals. Firstly, according to the physiological function of human defecation, bowel sound signals were selected for monitoring and analysis before defecation, and a portable non-invasive bowel sound collection system was built. Then, the detector algorithm based on iterative kurtosis and the signal processing method based on Kalman filter was used to process the signal to remove the aliasing noise in the bowel sound signal, and feature extraction was carried out in the time domain, frequency domain, and time–frequency domain. Finally, BP neural network was selected to build a classification training method for the features of bowel sound signals. (3) Results: Experimental results based on real data sets show that the proposed method can converge to a stable state and achieve a prediction accuracy of 88.71% in 232 records, which is better than other classification methods. (4) Conclusions: The result indicates that the proposed method could provide a high-precision defecation prediction result for patients with fecal incontinence, so as to prepare for defecation in advance.
Mobile Forensics: Repeatable and Non-Repeatable Technical Assessments
Authors: Cuomo Raffaele , D’Agostino Davide , Ianulardo Mario
Published: September 2022

This paper presents several scenarios where digital evidence can be collected from mobile devices, their legal value keeping untouched. The paper describes a robust methodology for mobile forensics developed through on-field experiences directly gained by the authors over the last 10 years and many real court cases. The results show that mobile forensics, digital analysis of smartphone Android or iOS can be obtained in two ways: on the one hand, data extraction must follow the best practice of the repeatability procedure; on the other hand, the extraction of the data must follow the best practice of the non-repeatability procedure. The laboratory study of the two methods for extracting digital data from mobile phones, for use as evidence in court trials, has shown that the same evidence can be obtained even when the procedure of unavailability of file mining activities has been adopted. Indeed, thanks to laboratory tests, the existence of multiple files frequently and continuously subjected to changes generated by the presence of several hashes found at forensic extractions conducted in very short moments of time (sometimes not exceeding 15 min) has been proven. If, on the other hand, the examination of a device is entrusted to a judicial police officer in order to conduct a forensic analysis to acquire data produced and managed by the user (such as images, audio, video, documents, SMS, MMS, chat conversations, address book content, etc.) we have sufficient grounds to believe that such examination can be organized according to the system of repeatable technical assessments.
Sub-Surface Defect Depth Approximation in Cold Infrared Thermography
Authors: Doshvarpassand Siavash , Wang Xiangyu
Published: September 2022

Detection and characterisation of hidden corrosion are considered challenging yet crucial activities in many sensitive industrial plants where preventing the loss of containment or structural reliability are paramount. In the last two decades, infrared (IR) thermography has proved to be a reliable means for inspection of corrosion or other sub-surface anomalies in low to mid thickness metallic mediums. The foundation of using IR thermography for defect detection and characterisation is based on active thermography. In this method of inspection, an external excitation source is deployed for the purpose of stimulating thermal evolutions inside objects. The presence of sub-surface defects disrupts the evolution of electromagnetic pulse inside an object. The reflection of altered pulse at the surface can be recorded through thermal camera in the form of temperature anomalies. Through authors’ previous works, cold thermography has shown that it can be a viable defect detection alternative to the most commonly used means of active thermography, known as heating. In the current work, the characterisation of defect dimensions, i.e., depth and diameter, has been explored. A simple analytical model for thermal contrast over defect is used in order to approximate the defect depth and diameter. This is achieved by comparing the similarities of the model and the experimental contrast time-series. A method of time-series similarity measurement known as dynamic time wrapping (DTW) is used to score the similarity between a pair of model and experiment time-series. The final outcome of the proposed experimental setup has revealed that there is a good potential to predict the metal loss of up to 50% in mid-thickness substrate even by deploying a less accurate nonradiometric thermal device and no advanced image processing.
An Infrastructure for Enabling Dynamic Fault Tolerance in Highly-Reliable Adaptive Distributed Embedded Systems Based on Switched Ethernet
Authors: Ballesteros Alberto , Barranco Manuel , Proenza Julián , Almeida Luís , Pozo Francisco , Palmer-Rodríguez Pere
Published: September 2022

Distributed Embedded Systems (DESs) carrying out critical tasks must be highly reliable and hard in real-time. Moreover, to operate in dynamic operational contexts in an effective and efficient manner, they must also be adaptive. Adaptivity is particularly interesting from a dependability perspective, as it can be used to develop dynamic fault tolerance mechanisms, which, in combination with static ones, make it possible to provide better and more efficient fault tolerance. However, constructing a DES with such complexity presents many challenges. This is because all the mechanisms that support fault tolerance, real-time, and adaptivity must be designed to operate in a coordinated manner. This paper presents the Dynamic Fault Tolerance for Flexible Time-Triggered Ethernet (DFT4FTT), a self-reconfigurable infrastructure for implementing highly reliable adaptive DES. Here, we describe the design of its hardware and software architecture and the main set of mechanisms, with a focus on fault tolerance.
Sárgaréz lemez lézeres vágása
Authors: Fábián Enikő Réka , Czigány Bence
Published: September 2022

A rézötvözetek lézeres vágása kihívást jelent ezen anyagokon a lézerfény jelentős visszaverődése miatt. A CO 2 lézeres vágás paramétereinek hatástanulmányát sárgaréz lemezeken végeztük. A technológiai beállí- tások változtatásainak eredményéül kapott vágási rések tanulmányozása alapján választottuk ki a legmeg- felelőbb beállításokat. A 2,5 mm vastagságú sárgaréz lemezen a legszebb vágási felületet grafittal bevont felületnél kaptuk, amikor a fókuszfolt helyzete 0,8 mm-re volt a lemezfelület alatt, a lézerteljesítmény 2500 W, az impulzusfrekvencia 200 Hz és a haladási sebesség 1400 mm/min volt. Az alkalmazott munkagáz minden esetben nitrogén volt.
Mátrixanyagukban erősített, kerámia gömbhéjjal töltött szintaktikus fémhabok
Authors: Maróti János Endre , Szovák Benedek , Orbulov Imre Norbert
Published: September 2022

A szintaktikus fémhabok olyan cellás szerkezetű anyagok, amelyekben a mátrixanyag fém, és ebben a befog- laló anyagban találhatóak töltőanyag bejuttatásával kialakított cellák. Ezek az anyagok kis sűrűségük mellett jó törőszilárdsággal és energiaelnyelő képességgel rendelkeznek. Ezen tulajdonságok javítását céloztuk meg a kutatás során kerámia erősítőanyag mátrixanyagba való bejuttatásával. A kísérletek során C795 alumí- nium-oxid kerámia gömbhéj töltőanyag és kerámia erősítőanyag keveréke közé infiltráltunk A356 alumí- niumötvözet (7Si-0,3Mg) olvadékot. A gyártást kisnyomásos infiltrációs öntéssel végeztük. Több eltérő erő- sítőanyagot vizsgáltunk, három eltérő szemcseméretű alumínium-oxidot és egy típusú szilícium-karbidot. A mintákat hőkezeltük, majd szabványos zömítővizsgálatnak vetettük alá. A mérések során kapott eredmé- nyeket az erősítetlen minták eredményeivel hasonlítottuk össze.
Túlmaródás hatásának vizsgálata színes maratás során
Authors: Renkó József Bálint , Szabó Péter János
Published: September 2022

A metallográfiában használatos színes maratás során a vizsgált szövetszerkezet folyamatos, ciklikus színvál- tozáson megy keresztül. Ez a színváltozás egy folyamatos fényintenzitás-vesztéssel jár együtt. Ha a maratást nem állítjuk meg időben, a szemcsék túlmaródnak. Ennek hatására a szövetszerkezet egyes elemeinek elkü- löníthetősége nagymértékben romlik, ami jelentős információvesztéssel járhat. Munkánk során azt vizsgál- tuk, hogyan lehet meghatározni a túlmaródás pillanatát az egyes szemcsékre vonatkoztatva. A maratás in-si- tu megfigyelése közben a kiindulási állapotra normált lumineszcenciában mérve meghatároztuk, mikortól tekinthető egy szemcse túlmartnak.
Gestión de riesgos de desastres y su influencia en la conciencia ambiental del Perú
Authors: Sifuentes Palomino Nora Patricia , Sifuentes Palomino Lucía Mercedes , Sifuentes Palomino Jesús Manuel , Ortiz Arias Rigoberto Carlos
Published: September 2022

La gestión riesgo y la educación ambiental es un área transdiciplinaria y actualmente le compete a los campos políticos, económicos y socioculturales mundiales. Esta investigación tuvo como propósito determinar la incidencia entre la gestión de riesgos de desastre y la conciencia ambiental en la I.E. José María Eguren Barranco, 2021, diseñando un estudio tipo básico correspondiente a un diseño no experimental de nivel correlacional causal de corte transeccional, aplicado a una población censal de 80 docentes. En esta investigación se utilizó dos instrumentos para medir las variables que se validaron por expertos, los resultados se procesaron en pruebas estadísticas del chi-cuadrado de cada componente, permitiéndonos así al ser el p-valor <0,05 demuestra la dependencia entre la variable independiente con la dependiente y dimensiones, de acuerdo al índice del pseudo cuadrado de Nagelkerke 0,333 y al p valor de 0,000.se ha demostrado que la variable gestión de riesgo presenta sobre la variable conciencia ambiental una dependencia de 33,3%. Se concluye que la gestión de riesgos influye de forma media y baja en las dimensiones de la investigación.
Estilos parentales y disciplina escolar en estudiantes del Perú
Authors: Espinoza Ibarra Carmen Patricia , Espinoza Ibarra Percy Elmer , Espinoza Ibarra Haydee Jenny , Llerena Espinoza Greyssi Lizette
Published: September 2022

La familia ha constituido el núcleo del desarrollo de cada sociedad y su rol en cuanto a la crianza de los hijos es vital para el desarrollo de los mismos, como buenos ciudadanos. El propósito de la investigación fue analizar la relación entre disciplina escolar y estilos parentales para ahondar en las particularidades del contexto estudiantil peruano. Se empleó el método hipotético – deductivo, ya que se partió de la observación. La población fue tomada como unidad de análisis y la muestra conformada por 136 alumnos del primero de secundaria del colegio José Abelardo Quiñonez Gonzales de Los Olivos. Los resultados condujeron que hay una relación considerable de 60.4% entre las variables disciplina escolar y estilos parentales.
DESEMPEÑO ESTACIONAL DEL ROSAL EN LA GENERACIÓN DE BROTES BASALES CON REGULADORES DE CRECIMIENTO
Authors: Gómora-Rasso Janet , Mejía-Carranza Jaime , Alvarado-Navarro Rafael , Ramírez-Gerardo Marithza G. , Ramírez-Dávila José F.
Published: September 2022

El cultivo de rosa de corte (Rosa spp.) en México destaca entre las actividades que más recursos económicos crea en el sector florícola. En la producción comercial de rosa, la generación de brotes basales por planta (BPP) de tipo productivo, que dan origen a tallos florales, se ve limitada por factores fisiológicos y ambientales, que aumentan BPP inferiores cortos denominados ‘ciegos’. El objetivo de la presente investigación fue evaluar el efecto de diferentes reguladores de crecimiento y un suplemento nutricional en el número y calidad de brotes basales de rosa durante las cuatro estaciones del año. El experimento se estableció en invernadero con 696 plantas de rosa cultivar Samourai bajo un diseño de bloques completos al azar con arreglo en parcelas divididas. Se aplicaron arriba del punto de injerto cinco tratamientos a base de citocininas (C), giberelinas (G), auxinas (A), complejo C + G + A (CGA), nitrógeno-calcio (NCa) y un testigo (T). Se contabilizaron las plantas con brotes basales (PCB) y BPP totales, productivos y ciegos y se analizaron mediante análisis de varianza, comparación de medias y correlaciones de Pearson. Hubo diferencias significativas (P ≤ 0.05) en PCB y la comparación de medias (Tukey, P ≤ 0.05) determinó que el tratamiento A de invierno promovió el mayor valor. La interacción estación × tratamiento fue altamente significativa (P ≤ 0.01), destacando un incremento de 50 % en PCB promedio de A, C, G, CGA y NCa con respecto a T en invierno, comparado con las demás estaciones, cuyo valor fue próximo a cero. Hubo diferencias significativas (P ≤ 0.05) en BPP productivos, ciegos y totales, con valores mayores de A en invierno para las tres categorías. En la proporción BPP productivos/BPP ciegos, CGA fue el mejor. Se concluye que CGA disminuye BPP ciegos y aumenta BPP productivos con influencia en un mayor número de tallos florales.
VARIACIÓN GENÉTICA ALTITUDINAL DE LA MORFOLOGÍA DE PLÁNTULAS DE Enterolobium cyclocarpum EN OAXACA, MÉXICO
Authors: Velasco-García Mario Valerio , Quino-Pascual Karen , Viveros-Viveros Héctor , Sánchez-Viveros Gabriela , Sáenz-Romero Cuauhtémoc , Hernández-Hernández María Luisa , Pineda-Posadas Jorge Alberto , Galán-Larrea Rolando
Published: September 2022

Enterolobium cyclocarpum (Jacq.) Griseb. es un árbol que se usa en programas de reforestación y restauración ecológica; sin embargo, se desconoce la variación altitudinal de la morfología de las plántulas, la cual puede ser un indicador de la adaptación de la especie a las condiciones ambientales de los sitios donde se puede establecer de manera exitosa. Los objetivos de este estudio fueron evaluar la variación morfológica de plántulas de E. cyclocarpum y determinar su relación con la altitud y con variables climáticas del sitio de origen de la semilla. Once variables morfológicas de plántulas de 10 procedencias se evaluaron en vivero. Diferencias significativas (P ≤ 0.05) entre procedencias se detectaron en nueve variables. En promedio, la aportación de las procedencias a la varianza total fue de 5.08 %. La asociación entre la altura de las plántulas con los grados día del sitio de origen fue negativa, lo mismo entre el ancho de las hojas verdaderas con la temperatura mínima y grados día > 5 °C del sitio de las procedencias. La altura y el diámetro a la altura de hipocótilo de las plántulas tuvieron asociación lineal positiva con la elevación del sitio de origen (R2 = 0.55, P = 0.0136; R2 = 0.41, P = 0.0456, respectivamente). Las semillas procedentes de mayor altitud originan plántulas de mayor tamaño, lo que se puede deber a una repuesta adaptativa de la especie o a efectos maternos relacionados con el tamaño de las semillas.
Diﬀerent response criteria to cardiac resynchronization therapy in patients with congestive heart failure
Authors: Soldatova A. M. , Kuznetsov V. A. , Malishevskaya D. S. , Malishevskii L. M. , Enina T. N. , Gorbatenko E. A.
Published: September 2022

Aim. To investigate the agreement among diﬀerent response criteria to cardiac resynchronization therapy (CRT) and long-term mortality in patients with congestive heart failure (CHF).

Methods. The study enrolled 141 patients (men 77.3%; women 22.7%) with CHF (65.2% ischemic and 34.8% non-ischemic etiology). Mean age was 58.6 [53.0;66.0] years. All patients had NYHA II-IV, left ventricular ejection fraction (LVEF) ≤35%; QRS ≥130 мs and/or left bundle branch block. Mean follow-up period was 45.0±34.2 months. Response to CRT was deﬁned according to dynamics of NYHA functional class, LVEF, and left-ventricular end-systolic volume (LVESV).

Results. Moderate agreement was found among LVEF and LVESV (Cohen’s k coeﬃcient 0.591±0.068) while we did not ﬁnd the agreement among echocardiographic criteria and NYHA. Long-term mortality had moderate negative correlation with LVESV (r=-0.486; p

Conclusion. Agreement between diﬀerent criteria to deﬁne response to CRT is poor. The strongest correlation with long-term mortality was found for LVESV. This inconsistency among diﬀerent response criteria severely limits the ability to generalize results over multiple CRT studies.
Image resolution enhancement via sparse interpolation on wavelet domain
Authors: Chavez Román , Ponomaryow Volodymyr , Castro Fernando
Published: September 2022

The image processing algorithms collectively known as super-resolution (SR) have proven effective in producing high-quality imagery from low-resolution (LR) images. This paper focuses on a novel image resolution enhancement method employing the wavelet domain techniques. In order to preserve more edge information, additional edge extraction step is proposed employing high-frequency (HF) sub-band images - low-high (LH), high-low (HL), and high-high (HH) - via the Discrete Wavelet Transform (DWT). In the designed procedure, the LR image is used in the sparse interpolation for the resolution-enhancement obtaining low-low (LL) sub- band. Additionally, all sub-bands (LL, LH, HL and HH) are performed via the Lanczos interpolation. Finally, the estimated sub-band images are used to form the new high-resolution (HR) image using the inverse DWT (IDWT). Experimental results on real data sets have confirmed the effectiveness of the proposed framework in terms of objective criteria as well as in subjective perception.
Una aproximación al poemario Ángel en el País del Águila (1954) de Ángel Martínez Baigorri: génesis, estructura y temas
Authors: Mata Indurain Carlos
Published: September 2022

Este trabajo analiza el poemario Ángel en el País del Águila de Ángel Martínez Baigorri (1899-1971). Publicado por primera vez en España (1954), más tarde quedaría recogido en el volumen Poesías completas I, en edición de Emilio del Río (1999). Se estudia su génesis (durante la estancia del poeta en Estados Unidos, entre agosto de 1946 y finales de 1947), su estructura (externa e interna) y los temas (además de la descripción de algunas ciudades estadounidenses como Nueva Orleans y Nueva York, el tema nuclear es la lucha del Ángel –‘el mundo del espíritu’– por entrar dentro del Águila –‘el mundo material’– e insuflarle nueva y más alta vida).
Contribución al estudio de la Piptadenia Cebil Gris
Authors:   , Zelada Fidel
Published: September 2022

Cuando elegí por tema de tesis la investigación del Cebil, pensé sacar el mayor provecho posible, agotando, por decir así, la materia de estudio que me ofrecía. Pensé también que, al proceder de esa manera, cumplía con un deber impuesto por la importancia de la profesión elegida, como guiado por el interés de presentaros un trabajo completo y provechoso. Nunca, como en este momento de prueba trascendental, he envidiado las grandes dotes intelectuales, que se destacan con caracteres propios, en provecho de las aspiraciones justas de renombre y de los beneficios generales que reporta. Pero si nos está vedado superar nuestros alcances, nos es permitido poner a prueba la voluntad que dignifica y nos consagra por entero al trabajo. En consecuencia, ofrezco a vuestra consideración y beneplácito este trabajo que llamo: Contribución al estudio de la Piptadenia Cebil, que es el resultado de mis conocimientos y dedicación, vigorizados por esa voluntad compañera inseparable de mis esfuerzos de estudiante. El estudio que os presento abarca: la descripción botánica, descripción histológica de la corteza, composición química de los taninos, evaluación del tanino, descripción de diferentes métodos de valoración y la clasificación, el análisis inmediato, el de las cenizas de la corteza y el de la goma exudada por el Cebil. No me ha sido posible estudiar la materia colorante, ni la naturaleza química del tanino y resinas que posee y acaso algún principio activo; pero obligóme a emprenderlo oportunamente, de modo de poner a prueba que vuestras lecciones y consejos siguen practicándose.
Aprendizajes significativos en la formación de terapeutas familiares de la Universidad Católica Luis Amigó
Authors: Herrera Rivera Ovidio , Bedoya Cardona Ledy Maryory
Published: September 2022

Formar-se cómo terapeuta familiar induce a pensar en procesos de intervención con las familias, pero también consigo mismo. En este sentido, el objetivo del estudio se centró en identificar aprendizajes significativos desde el ser, hacer y saber de terapeutas en formación, durante el curso de entrenamiento, adscrito a la Especialización en Terapia Familiar de la Universidad Católica Luis Amigó. En sintonía con estos intereses, la investigación fue de corte cualitativo, al habilitar contextos interpretativos de experiencias vinculadas al proceso formativo; al respecto, la organización, sistematización y análisis de información estuvo mediada por el método de análisis de contenido (AC); metodología que busca trascender lo subjetivo a procesos de objetivación, mediante el uso de técnicas e instrumentos, como la entrevista a profundidad. Acorde con los resultados, se encontró que los aprendizajes de los estudiantes están estrechamente vinculados con el ser, hacer y saber, como meta-aprendizajes para la vida. El estudio concluye que el proceso de formación de terapeutas familiares induce ineludiblemente a una perspectiva holística de la realidad personal, familiar y social, que conjuga aprendizajes significativos, vistos como puntos de partida para confrontar y evaluar procesos de transformación, mediatizados por la autoreflexividad y la confrontación personal y familiar, que van más allá de las teorías formativas.
 
Palabras clave: Aprendizaje, aprendizajes significativos, formación en terapia familiar, terapia familiar.
Niveles de percepción de estrés en época de COVID-19, a causa de la virtualidad, en estudiantes universitarios, Barranquilla-Colombia
Authors: Castro-Vásquez Leyn , Bedoya Valencia Daniel , Estrada-Matallana Laura
Published: September 2022

Con el fin de establecer la percepción de estrés en estudiantes de primer semestre de la Universidad Metropolitana-Barranquilla, se utilizó un cuestionario Likert como instrumento de recolección de datos, estructurado con 27 interrogantes sobre estresores relacionados con las clases virtuales, donde el estudiante, según su percepción, debía responder a niveles de estrés: Normal, Leve, Moderado y Severo. Obteniéndose que los estresores con mayores niveles de percepción fueron el exceso de actividades académicas, la red inestable de internet y la interrupción en el fluido eléctrico; también, se observó que el nivel de percepción estrés severo fue ligeramente mayor en las mujeres, comparado con los hombres; se encontró, además, que algunos programas académicos presentan mayor nivel de percepción de estrés, lo cual se explicaría por la cantidad de mujeres matriculadas en los programas, y como se dijo anteriormente, los niveles de percepción de estrés en las mujeres son más altos, comparados con los hombres. Por otra parte, el nivel de estrés percibido no mostró dependencia de la edad (p: 0,1471). Por último, se proponen estrategias para reducir los niveles de estrés, que pueden ser implementadas en la Universidad Metropolitana y en otras instituciones educativas.
التحقق من صدق اختبار رمي كرة السلة لقياس القوة العضلية للجزء العلوي من الجسم عند تلاميذ المدارس الابتدائية الجزائرية
Authors: Belhaidas Mohammed Besseddik  , Dahoune Oumri  , Benkhaled Elhadj
Published: September 2022

الهدف من دراستنا هو التحقق من صدق اختبار رمي كرة السلة لتقييم القوة العضلية للجزء العلوي من الجسم لأطفال المدارس الابتدائية ، ولهذا الغرض استخدمنا المنهج الوصفي بالأسلوب المسحي على عينة مكونة من 65 تلميذ من المدرسة الابتدائية (33 ذكور ، 32 اناث)، متوسط العمر 8،75 سنة، الانحراف المعياري 1.47 سنة تم اختيارها عشوائيًا، ولجمع البيانات استخدمنا شريط قياس مرنًا و ميزان (لقياس الطول والوزن على التوالي) من أجل اخذ القياسات الانثروبومترية، واختبار رمي كرة السلة واختبار قبضة اليد (اختبار محكي) لقياس القوة العضلية للجزء العلوي من الجسم. بعد جمع البيانات ومعالجتها إحصائيًا، نستنتج أن اختبار رمي كرة السلة هو مقياس صادق في قياس القوة العضلية للجزء العلوي من الجسم لأطفال المدارس الابتدائية ويتأثر قليلاً بمؤشر كتلة الجسم. على هذا الأساس، أوصت الدراسة بالتحقق من موضوعية و ثبات هذا الاختبار على عينات مختلفة و من ثم تضمينه في بطاريات اختبار اللياقة البدنية المرتبطة بالصحة.