bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figures from Ribosomal Protein Rpl22 Controls the Dissemination of T-cell Lymphoma
Authors: Rao Shuyun , Cai Kathy Q. , Stadanlick Jason E. , Greenberg-Kushnir Noa , Solanki-Patel Nehal , Lee Sang-Yun , Fahl Shawn P. , Testa Joseph R. , Wiest David L.
Published: April 2023

This file contains supplementary figures 1-4. Supplementary Figure 1 provides supporting information for the effects of Rpl22 loss on thymic cellularity and supports Figure 1. Supplementary Figure 2 describes the phenotypes of periperhal T lineage cells, both normal and transformed, in Rpl22-sufficient and Rpl22-deficient mice. It supports the data in Figure 3. Supplementary Figure 3 depicts the maturation of single positive thymocytes in MyrAkt Tg Rpl22-deficient mice, revealing that maturation is not impaired. These data support Figure 5. Supplementary figure 4 depicts the effect of Rpl22 mutation on expression of KLF2 and S1PR1 in human T-ALL. It supports the data in Figure 6.
Supplementary Table S3 from miR-146b-5p within BCR-ABL1–Positive Microvesicles Promotes Leukemic Transformation of Hematopoietic Cells
Authors: Zhang Hong-Mei , Li Qing , Zhu Xiaojian , Liu Wei , Hu Hui , Liu Teng , Cheng Fanjun , You Yong , Zhong Zhaodong , Zou Ping , Li Qiubai , Chen Zhichao , Guo An-Yuan
Published: April 2023

Supplementary Table S3. GO enrichment for DEGs in three stages
Supplementary figure legends 1-6 from CK2α' Drives Lung Cancer Metastasis by Targeting BRMS1 Nuclear Export and Degradation
Authors: Liu Yuan , Amin Elianna B. , Mayo Marty W. , Chudgar Neel P. , Bucciarelli Peter R. , Kadota Kyuichi , Adusumilli Prasad S. , Jones David R.
Published: April 2023

Legends for Supplementary Figures S1-S6.
Supplementary Figure 8 from Galectin-3 Cleavage Alters Bone Remodeling: Different Outcomes in Breast and Prostate Cancer Skeletal Metastasis
Authors: Nakajima Kosei , Kho Dhong Hyo , Yanagawa Takashi , Harazono Yosuke , Hogan Victor , Chen Wei , Ali-Fehmi Rouba , Mehra Rohit , Raz Avraham
Published: April 2023

Cancer patient's IgG does not recognize CRD of Gal-3.
Supplemental Figure Legends from Aberrant Notch Signaling in the Bone Marrow Microenvironment of Acute Lymphoid Leukemia Suppresses Osteoblast-Mediated Support of Hematopoietic Niche Function
Authors: Wang Weihuan , Zimmerman Grant , Huang Xiaoran , Yu Shuiliang , Myers Jay , Wang Yiwei , Moreton Stephen , Nthale Joseph , Awadallah Amad , Beck Rose , Xin Wei , Wald David , Huang Alex Y. , Zhou Lan
Published: April 2023

Supplemental Figure Legends
Supplementary Figure 4 from Galectin-3 Cleavage Alters Bone Remodeling: Different Outcomes in Breast and Prostate Cancer Skeletal Metastasis
Authors: Nakajima Kosei , Kho Dhong Hyo , Yanagawa Takashi , Harazono Yosuke , Hogan Victor , Chen Wei , Ali-Fehmi Rouba , Mehra Rohit , Raz Avraham
Published: April 2023

Created customized anti-CRD antibody recognizes CRD of Gal-3.
Supplementary Methods and Figure Legends from STAT3 Establishes an Immunosuppressive Microenvironment during the Early Stages of Breast Carcinogenesis to Promote Tumor Growth and Metastasis
Authors: Jones Laura M. , Broz Miranda L. , Ranger Jill J. , Ozcelik John , Ahn Ryuhjin , Zuo Dongmei , Ursini-Siegel Josie , Hallett Michael T. , Krummel Matthew , Muller William J.
Published: April 2023

Supplementary Methods and Figure Legends
Supplementary Figure S5 from Macrophage Infiltration and Alternative Activation during Wound Healing Promote MEK1-Induced Skin Carcinogenesis
Authors: Weber Christine , Telerman Stephanie B. , Reimer Andreas S. , Sequeira Ines , Liakath-Ali Kifayathullah , Arwert Esther N. , Watt Fiona M.
Published: April 2023

Arginase expression analysis
Supplementary Figure S8 from Comprehensive Ex Vivo Transposon Mutagenesis Identifies Genes That Promote Growth Factor Independence and Leukemogenesis
Authors: Guo Yabin , Updegraff Barrett L. , Park Sunho , Durakoglugil Deniz , Cruz Victoria H. , Maddux Sarah , Hwang Tae Hyun , O'Donnell Kathryn A.
Published: April 2023

Expression of pooled CIS genes in Ba/F3 cells.
Supplementary Figure S2 from Macrophage Infiltration and Alternative Activation during Wound Healing Promote MEK1-Induced Skin Carcinogenesis
Authors: Weber Christine , Telerman Stephanie B. , Reimer Andreas S. , Sequeira Ines , Liakath-Ali Kifayathullah , Arwert Esther N. , Watt Fiona M.
Published: April 2023

Manual quantification of CD11b+F4/80+ and F4/80+ cells in the dermis of InvEE and WT skin during different wound healing time points and in unwounded skin
Supplementary Figure S5 from Comprehensive Ex Vivo Transposon Mutagenesis Identifies Genes That Promote Growth Factor Independence and Leukemogenesis
Authors: Guo Yabin , Updegraff Barrett L. , Park Sunho , Durakoglugil Deniz , Cruz Victoria H. , Maddux Sarah , Hwang Tae Hyun , O'Donnell Kathryn A.
Published: April 2023

Expression of individual CIS genes are associated with survival of AML patients.
Supplementary Figure S3 from Comprehensive Ex Vivo Transposon Mutagenesis Identifies Genes That Promote Growth Factor Independence and Leukemogenesis
Authors: Guo Yabin , Updegraff Barrett L. , Park Sunho , Durakoglugil Deniz , Cruz Victoria H. , Maddux Sarah , Hwang Tae Hyun , O'Donnell Kathryn A.
Published: April 2023

Consensus clustering analysis of 4898 CIS genes in human AML and expression of CIS genes in high-risk and low-risk ALL patient subgroups.
Supplementary Figure S2 from Comprehensive Ex Vivo Transposon Mutagenesis Identifies Genes That Promote Growth Factor Independence and Leukemogenesis
Authors: Guo Yabin , Updegraff Barrett L. , Park Sunho , Durakoglugil Deniz , Cruz Victoria H. , Maddux Sarah , Hwang Tae Hyun , O'Donnell Kathryn A.
Published: April 2023

Relevance to human leukemia and pathway analysis of CIS genes.
Supplementary Figure S13 from Comprehensive Ex Vivo Transposon Mutagenesis Identifies Genes That Promote Growth Factor Independence and Leukemogenesis
Authors: Guo Yabin , Updegraff Barrett L. , Park Sunho , Durakoglugil Deniz , Cruz Victoria H. , Maddux Sarah , Hwang Tae Hyun , O'Donnell Kathryn A.
Published: April 2023

CRISPR/Cas9-mediated inhibition of USP32 reduces proliferation in vitro and prolongs survival in vivo.
Supplementary Figure S12 from Comprehensive Ex Vivo Transposon Mutagenesis Identifies Genes That Promote Growth Factor Independence and Leukemogenesis
Authors: Guo Yabin , Updegraff Barrett L. , Park Sunho , Durakoglugil Deniz , Cruz Victoria H. , Maddux Sarah , Hwang Tae Hyun , O'Donnell Kathryn A.
Published: April 2023

Analysis of myeloid and lymphoid lineage markers in tumors.
Supplementary Dataset S1 from Comprehensive Ex Vivo Transposon Mutagenesis Identifies Genes That Promote Growth Factor Independence and Leukemogenesis
Authors: Guo Yabin , Updegraff Barrett L. , Park Sunho , Durakoglugil Deniz , Cruz Victoria H. , Maddux Sarah , Hwang Tae Hyun , O'Donnell Kathryn A.
Published: April 2023

All CIS genes identified in the comprehensive Ba/F3 mutagenesis screen.
Supplementary Table 3 from Antagonizing Integrin β3 Increases Immunosuppression in Cancer
Authors: Su Xinming , Esser Alison K. , Amend Sarah R. , Xiang Jingyu , Xu Yalin , Ross Michael H. , Fox Gregory C. , Kobayashi Takayuki , Steri Veronica , Roomp Kirsten , Fontana Francesca , Hurchla Michelle A. , Knolhoff Brett L. , Meyer Melissa A. , Morgan Elizabeth A. , Tomasson Julia C. , Novack Joshua S. , Zou Wei , Faccio Roberta , Novack Deborah V. , Robinson Stephen D. , Teitelbaum Steven L. , DeNardo David G. , Schneider Jochen G. , Weilbaecher Katherine N.
Published: April 2023

Antibody list for FACS
Supplementary Figure 7 from Antagonizing Integrin β3 Increases Immunosuppression in Cancer
Authors: Su Xinming , Esser Alison K. , Amend Sarah R. , Xiang Jingyu , Xu Yalin , Ross Michael H. , Fox Gregory C. , Kobayashi Takayuki , Steri Veronica , Roomp Kirsten , Fontana Francesca , Hurchla Michelle A. , Knolhoff Brett L. , Meyer Melissa A. , Morgan Elizabeth A. , Tomasson Julia C. , Novack Joshua S. , Zou Wei , Faccio Roberta , Novack Deborah V. , Robinson Stephen D. , Teitelbaum Steven L. , DeNardo David G. , Schneider Jochen G. , Weilbaecher Katherine N.
Published: April 2023

Integrin beta3 regulates STAT6 signaling
Supplementary Figure 1 from Myeloid-Derived Suppressor Cells Endow Stem-like Qualities to Breast Cancer Cells through IL6/STAT3 and NO/NOTCH Cross-talk Signaling
Authors: Peng Dongjun , Tanikawa Takashi , Li Wei , Zhao Lili , Vatan Linda , Szeliga Wojciech , Wan Shanshan , Wei Shuang , Wang Yin , Liu Yan , Staroslawska Elzbieta , Szubstarski Franciszek , Rolinski Jacek , Grywalska Ewelina , Stanisławek Andrzej , Polkowski Wojciech , Kurylcio Andrzej , Kleer Celina , Chang Alfred E. , Wicha Max , Sabel Michael , Zou Weiping , Kryczek Ilona
Published: April 2023

MDSC phenotype and suppressor activity
Supplementary Table 2 from An Anti-EGFR IgA That Displays Improved Pharmacokinetics and Myeloid Effector Cell Engagement In Vivo
Authors: Lohse Stefan , Meyer Saskia , Meulenbroek Laura A.P.M. , Jansen J.H. Marco , Nederend Maaike , Kretschmer Anna , Klausz Katja , Möginger Uwe , Derer Stefanie , Rösner Thies , Kellner Christian , Schewe Denis , Sondermann Peter , Tiwari Sanjay , Kolarich Daniel , Peipp Matthias , Leusen Jeanette H.W. , Valerius Thomas
Published: April 2023

N-glycan structures of 225-IgA2-wt and 225-IgA2.0 identified by PGC-LC ESI MS/MS.
Supplementary figure 3 from Abscopal Effects of Radiotherapy Are Enhanced by Combined Immunostimulatory mAbs and Are Dependent on CD8 T Cells and Crosspriming
Authors: Rodriguez-Ruiz María E. , Rodriguez Inmaculada , Garasa Saray , Barbes Benigno , Solorzano Jose Luis , Perez-Gracia Jose Luis , Labiano Sara , Sanmamed Miguel F. , Azpilikueta Arantza , Bolaños Elixabet , Sanchez-Paulete Alfonso R. , Aznar M. Angela , Rouzaut Ana , Schalper Kurt A. , Jure-Kunkel Maria , Melero Ignacio
Published: April 2023

Radiotherapy reduced the density and absolute numbers of CD4+, CD8+ and CD25+FOXP3+ T cells and Myeloid-derived suppressor cells both in the irradiated and non-irradiated lesions.
Supplementary Table S1 from A Heritable Missense Polymorphism in CDKN2A Confers Strong Risk of Childhood Acute Lymphoblastic Leukemia and Is Preferentially Selected during Clonal Evolution
Authors: Walsh Kyle M. , de Smith Adam J. , Hansen Helen M. , Smirnov Ivan V. , Gonseth Semira , Endicott Alyson A. , Xiao Jianqiao , Rice Terri , Fu Cecilia H. , McCoy Lucie S. , Lachance Daniel H. , Eckel-Passow Jeanette E. , Wiencke John K. , Jenkins Robert B. , Wrensch Margaret R. , Ma Xiaomei , Metayer Catherine , Wiemels Joseph L.
Published: April 2023

Subject characteristics of cases and controls undergoing genetic association analyses from the California Childhood Leukemia Study, The Children's Oncology Group, The Wellcome Trust Consortium, the GENEVA Melanoma Study, The University of California, San Francisco Adult Glioma Study, The Mayo Clinic glioma study, and the CGEMS PanScan pancreatic cancer case-control study.
Supplementary Figure 2 from Distinct Subtypes of Gastric Cancer Defined by Molecular Characterization Include Novel Mutational Signatures with Prognostic Capability
Authors: Li Xiangchun , Wu William K.K. , Xing Rui , Wong Sunny H. , Liu Yuexin , Fang Xiaodong , Zhang Yanlin , Wang Mengyao , Wang Jiaqian , Li Lin , Zhou Yong , Tang Senwei , Peng Shaoliang , Qiu Kunlong , Chen Longyun , Chen Kexin , Yang Huanming , Zhang Wei , Chan Matthew T.V. , Lu Youyong , Sung Joseph J.Y. , Yu Jun
Published: April 2023

Fig. S2: Prognostic significance of C1/2.
Supplemental Table S2 from Osteogenic Potential of Mesenchymal Stromal Cells Contributes to Primary Myelofibrosis
Authors: Martinaud Christophe , Desterke Christophe , Konopacki Johanna , Pieri Lisa , Torossian Frédéric , Golub Rachel , Schmutz Sandrine , Anginot Adrienne , Guerton Bernadette , Rochet Nathalie , Albanese Patricia , Henault Emilie , Pierre-Louis Olivier , Souraud Jean-Baptiste , de Revel Thierry , Dupriez Brigitte , Ianotto Jean-Christophe , Bourgeade Marie-Françoise , Vannucchi Alessandro M. , Lataillade Jean-Jacques , Le Bousse-Kerdilès Marie-Caroline
Published: April 2023

Hematopoiesis support by MSCs in LTBMC BFU-E, CFU-G, CFU-M and CFU-GM by PMF (n=3) and healthy donors (HD, n=3) expressed as number of colonies for 104 bone marrow mononuclear cells.
Supplemental Table from GON4L Drives Cancer Growth through a YY1–Androgen Receptor–CD24 Axis
Authors: Agarwal Neeraj , Dancik Garrett M. , Goodspeed Andrew , Costello James C. , Owens Charles , Duex Jason E. , Theodorescu Dan
Published: April 2023

The table shows qRT-PCR data for the knockdown of candidate genes in different bladder cancer cell lines transduced with shRNA containing lentivirus.
Supplementary table 1 from A Preclinical Model of Chronic Alcohol Consumption Reveals Increased Metastatic Seeding of Colon Cancer Cells in the Liver
Authors: Im Hwi-Jin , Kim Hyeong-Geug , Lee Jin-Seok , Kim Hyo-Seon , Cho Jung-Hyo , Jo Il-Joo , Park Sung-Joo , Son Chang-Gue
Published: April 2023

Serum biochemistry data and hepatic lipid profiles
Supplemental Figure 3 dNICD in Brat-RNAi brain localizes in nucleus. from Drosophila Brat and Human Ortholog TRIM3 Maintain Stem Cell Equilibrium and Suppress Brain Tumorigenesis by Attenuating Notch Nuclear Transport
Authors: Mukherjee Subhas , Tucker-Burden Carol , Zhang Changming , Moberg Kenneth , Read Renee , Hadjipanayis Costas , Brat Daniel J.
Published: April 2023

(A) Cytosolic extraction of brat-RNAi (bratIR) Drosophila brains shows higher levels of NICD compared to the control brain. (B) Nuclear extract also shows higher NICD in brat-RNAi compared to control suggesting increased NICD nuclear transport. (C) Densitometric quantification of nuclear NICD.
Supplementary methods from The Small Molecule IMR-1 Inhibits the Notch Transcriptional Activation Complex to Suppress Tumorigenesis
Authors: Astudillo Luisana , Da Silva Thiago G. , Wang Zhiqiang , Han Xiaoqing , Jin Ke , VanWye Jeffrey , Zhu Xiaoxia , Weaver Kelly , Oashi Taiji , Lopes Pedro E.M. , Orton Darren , Neitzel Leif R. , Lee Ethan , Landgraf Ralf , Robbins David J. , MacKerell Alexander D. , Capobianco Anthony J.
Published: April 2023

Explanation of experimental details for additional methods.
Supplemental Figure 3 from Cyclin A1 and P450 Aromatase Promote Metastatic Homing and Growth of Stem-like Prostate Cancer Cells in the Bone Marrow
Authors: Miftakhova Regina , Hedblom Andreas , Semenas Julius , Robinson Brian , Simoulis Athanasios , Malm Johan , Rizvanov Albert , Heery David M. , Mongan Nigel P. , Maitland Norman J. , Allegrucci Cinzia , Persson Jenny L.
Published: April 2023

Evaluate bone marrow metastasis initiated by PC3M cells via intracardiac injection of tumor cells into mice.
Supplemental Materials and Mehods from Notch4 Signaling Induces a Mesenchymal–Epithelial–like Transition in Melanoma Cells to Suppress Malignant Behaviors
Authors: Bonyadi Rad Ehsan , Hammerlindl Heinz , Wels Christian , Popper Ulrich , Ravindran Menon Dinoop , Breiteneder Heimo , Kitzwoegerer Melitta , Hafner Christine , Herlyn Meenhard , Bergler Helmut , Schaider Helmut
Published: April 2023

Supplemental Materials and Methods used to create Supplemental Figures only in addition to Materials and Methods listed in the main manuscript
Supplemental Figure 1 from JPO2/CDCA7L and LEDGF/p75 Are Novel Mediators of PI3K/AKT Signaling and Aggressive Phenotypes in Medulloblastoma
Authors: Chan Tiffany Sin Yu , Hawkins Cynthia , Krieger Jonathan R. , McGlade C. Jane , Huang Annie
Published: April 2023

JPO2 has limited effects on MB cell proliferation
Supplemental Figure 6: Analysis of spleens from APCMin mice. from HuR Small-Molecule Inhibitor Elicits Differential Effects in Adenomatosis Polyposis and Colorectal Carcinogenesis
Authors: Lang Michaela , Berry David , Passecker Katharina , Mesteri Ildiko , Bhuju Sabin , Ebner Florian , Sedlyarov Vitaly , Evstatiev Rayko , Dammann Kyle , Loy Alexander , Kuzyk Orest , Kovarik Pavel , Khare Vineeta , Beibel Martin , Roma Guglielmo , Meisner-Kober Nicole , Gasche Christoph
Published: April 2023

MS-444 restores splenic lymphoid follicles and decreases spleen weight in APCMin mice.
Supplementary Figures S1-S7 from Merlin/NF2 Suppresses Pancreatic Tumor Growth and Metastasis by Attenuating the FOXM1-Mediated Wnt/β-Catenin Signaling
Authors: Quan Ming , Cui Jiujie , Xia Tian , Jia Zhiliang , Xie Dacheng , Wei Daoyan , Huang Suyun , Huang Qian , Zheng Shaojiang , Xie Keping
Published: April 2023

Expression of Merlin in PDA tissues (S1); Effect of methylation on Merlin expression in PDA cell lines (S2); Restored expression and knockdown of Merlin in PDA cells (S3); Merlin suppressed PDA cell migration and invasion in vitro (S4); Merlin did not affect the expression levels of β-catenin and FOXM1 mRNA (S5); PAK1 mediated the suppressor function of Merlin on Wnt/β-catenin signaling (S6); Mechanisms underlying a reduced expression of Merlin in pancreatic cancer cells (S7).
Supplementary Tables 1 through 4 from An Immune-Inflammation Gene Expression Signature in Prostate Tumors of Smokers
Authors: Prueitt Robyn L. , Wallace Tiffany A. , Glynn Sharon A. , Yi Ming , Tang Wei , Luo Jun , Dorsey Tiffany H. , Stagliano Katherine E. , Gillespie John W. , Hudson Robert S. , Terunuma Atsushi , Shoe Jennifer L. , Haines Diana C. , Yfantis Harris G. , Han Misop , Martin Damali N. , Jordan Symone V. , Borin James F. , Naslund Michael J. , Alexander Richard B. , Stephens Robert M. , Loffredo Christopher A. , Lee Dong H. , Putluri Nagireddy , Sreekumar Arun , Hurwitz Arthur A. , Ambs Stefan
Published: April 2023

Supplementary Table S1: Clinical characteristics of the study population by smoking status. Supplementary Table S2: Immunoglobulin expression in prostate tumors by smoking status of the patients. Supplementary Table S3: Genes differently expressed between current and never smokers in prostate tumors. Supplementary Table S4: Genes differently expressed between current and never/past smokers in 67 prostate tumors.
Supplementary Table S1 from Src Inhibition Blocks c-Myc Translation and Glucose Metabolism to Prevent the Development of Breast Cancer
Authors: Jain Shalini , Wang Xiao , Chang Chia-Chi , Ibarra-Drendall Catherine , Wang Hai , Zhang Qingling , Brady Samuel W. , Li Ping , Zhao Hong , Dobbs Jessica , Kyrish Matt , Tkaczyk Tomasz S. , Ambrose Adrian , Sistrunk Christopher , Arun Banu K. , Richards-Kortum Rebecca , Jia Wei , Seewaldt Victoria L. , Yu Dihua
Published: April 2023

RPPA data showing fold changes in transcriptional regulator expressions in saracatinib treated 10A.B2 cells over vehicle control.
Supplementary Methods and References from Src Inhibition Blocks c-Myc Translation and Glucose Metabolism to Prevent the Development of Breast Cancer
Authors: Jain Shalini , Wang Xiao , Chang Chia-Chi , Ibarra-Drendall Catherine , Wang Hai , Zhang Qingling , Brady Samuel W. , Li Ping , Zhao Hong , Dobbs Jessica , Kyrish Matt , Tkaczyk Tomasz S. , Ambrose Adrian , Sistrunk Christopher , Arun Banu K. , Richards-Kortum Rebecca , Jia Wei , Seewaldt Victoria L. , Yu Dihua
Published: April 2023

Description of additional methods and procedures used in the study. Also includes Supplementary References.
Supplementary Methods from An Immune-Inflammation Gene Expression Signature in Prostate Tumors of Smokers
Authors: Prueitt Robyn L. , Wallace Tiffany A. , Glynn Sharon A. , Yi Ming , Tang Wei , Luo Jun , Dorsey Tiffany H. , Stagliano Katherine E. , Gillespie John W. , Hudson Robert S. , Terunuma Atsushi , Shoe Jennifer L. , Haines Diana C. , Yfantis Harris G. , Han Misop , Martin Damali N. , Jordan Symone V. , Borin James F. , Naslund Michael J. , Alexander Richard B. , Stephens Robert M. , Loffredo Christopher A. , Lee Dong H. , Putluri Nagireddy , Sreekumar Arun , Hurwitz Arthur A. , Ambs Stefan
Published: April 2023

Supplementary Methods
Supplementary Figure 4 from Checkpoint Antibodies but not T Cell–Recruiting Diabodies Effectively Synergize with TIL-Inducing γ-Irradiation
Authors: Hettich Michael , Lahoti Jayashree , Prasad Shruthi , Niedermann Gabriele
Published: April 2023

Kinetics of TIL influx and remaining tumor cells after hRT treatment of large tumors.
Supplementary Figure 2 from Checkpoint Antibodies but not T Cell–Recruiting Diabodies Effectively Synergize with TIL-Inducing γ-Irradiation
Authors: Hettich Michael , Lahoti Jayashree , Prasad Shruthi , Niedermann Gabriele
Published: April 2023

PD-1 and PD-L1 expression on cytotoxic T cells and tumor cells.
Supplementary Table S3 from Identification of MYC-Dependent Transcriptional Programs in Oncogene-Addicted Liver Tumors
Authors: Kress Theresia R. , Pellanda Paola , Pellegrinet Luca , Bianchi Valerio , Nicoli Paola , Doni Mirko , Recordati Camilla , Bianchi Salvatore , Rotta Luca , Capra Thelma , Ravà Micol , Verrecchia Alessandro , Radaelli Enrico , Littlewood Trevor D. , Evan Gerard I. , Amati Bruno
Published: April 2023

MycVD-sensitive genes.
Supplementary Methods and References from Identification of MYC-Dependent Transcriptional Programs in Oncogene-Addicted Liver Tumors
Authors: Kress Theresia R. , Pellanda Paola , Pellegrinet Luca , Bianchi Valerio , Nicoli Paola , Doni Mirko , Recordati Camilla , Bianchi Salvatore , Rotta Luca , Capra Thelma , Ravà Micol , Verrecchia Alessandro , Radaelli Enrico , Littlewood Trevor D. , Evan Gerard I. , Amati Bruno
Published: April 2023

Description of additional methods and procedures used in the study. Also includes Supplementary References.
Supplementary Table S3 from Integrated Classification of Prostate Cancer Reveals a Novel Luminal Subtype with Poor Outcome
Authors: You Sungyong , Knudsen Beatrice S. , Erho Nicholas , Alshalalfa Mohammed , Takhar Mandeep , Al-deen Ashab Hussam , Davicioni Elai , Karnes R. Jeffrey , Klein Eric A. , Den Robert B. , Ross Ashley E. , Schaeffer Edward M. , Garraway Isla P. , Kim Jayoung , Freeman Michael R.
Published: April 2023

The genes in the collection of pathway signatures used in this study.
Supplementary Table S2 from Neural Cell Adhesion Protein CNTN1 Promotes the Metastatic Progression of Prostate Cancer
Authors: Yan Judy , Ojo Diane , Kapoor Anil , Lin Xiaozeng , Pinthus Jehonathan H. , Aziz Tariq , Bismar Tarek A. , Wei Fengxiang , Wong Nicholas , De Melo Jason , Cutz Jean-Claude , Major Pierre , Wood Geoffrey , Peng Hao , Tang Damu
Published: April 2023

Affymetrix gene expression changes for CNTN1 overexpression and knockdown cell lines
Supplementary Figure S5 from Nestin Mediates Hedgehog Pathway Tumorigenesis
Authors: Li Peng , Lee Eric H. , Du Fang , Gordon Renata E. , Yuelling Larra W. , Liu Yongqiang , Ng Jessica M.Y. , Zhang Hao , Wu Jinhua , Korshunov Andrey , Pfister Stefan M. , Curran Tom , Yang Zeng-jie
Published: April 2023

Proliferation and Hh signaling in MB cells at 24hrs after Nestin depletion
Supplementary Figure 3 from Neural Cell Adhesion Protein CNTN1 Promotes the Metastatic Progression of Prostate Cancer
Authors: Yan Judy , Ojo Diane , Kapoor Anil , Lin Xiaozeng , Pinthus Jehonathan H. , Aziz Tariq , Bismar Tarek A. , Wei Fengxiang , Wong Nicholas , De Melo Jason , Cutz Jean-Claude , Major Pierre , Wood Geoffrey , Peng Hao , Tang Damu
Published: April 2023

The impact of CNTN1 on PC tumorigenesis.
Supplementary Figure S1 from Nestin Mediates Hedgehog Pathway Tumorigenesis
Authors: Li Peng , Lee Eric H. , Du Fang , Gordon Renata E. , Yuelling Larra W. , Liu Yongqiang , Ng Jessica M.Y. , Zhang Hao , Wu Jinhua , Korshunov Andrey , Pfister Stefan M. , Curran Tom , Yang Zeng-jie
Published: April 2023

Nestin expression in Hh type MB
Supplementary Figure 1 from Neural Cell Adhesion Protein CNTN1 Promotes the Metastatic Progression of Prostate Cancer
Authors: Yan Judy , Ojo Diane , Kapoor Anil , Lin Xiaozeng , Pinthus Jehonathan H. , Aziz Tariq , Bismar Tarek A. , Wei Fengxiang , Wong Nicholas , De Melo Jason , Cutz Jean-Claude , Major Pierre , Wood Geoffrey , Peng Hao , Tang Damu
Published: April 2023

Characterization of PC3 cells cultured under serum free PCSC culturing conditions.
Supplementary Methods and References from Multiregion Whole-Exome Sequencing Uncovers the Genetic Evolution and Mutational Heterogeneity of Early-Stage Metastatic Melanoma
Authors: Harbst Katja , Lauss Martin , Cirenajwis Helena , Isaksson Karolin , Rosengren Frida , Törngren Therese , Kvist Anders , Johansson Maria C. , Vallon-Christersson Johan , Baldetorp Bo , Borg Åke , Olsson Håkan , Ingvar Christian , Carneiro Ana , Jönsson Göran
Published: April 2023

Description of additional methods and procedures used in the study. Also includes Supplementary References.
Supplementary Figures S1-S15 from Multiregion Whole-Exome Sequencing Uncovers the Genetic Evolution and Mutational Heterogeneity of Early-Stage Metastatic Melanoma
Authors: Harbst Katja , Lauss Martin , Cirenajwis Helena , Isaksson Karolin , Rosengren Frida , Törngren Therese , Kvist Anders , Johansson Maria C. , Vallon-Christersson Johan , Baldetorp Bo , Borg Åke , Olsson Håkan , Ingvar Christian , Carneiro Ana , Jönsson Göran
Published: April 2023

Overview of the study workflow (S1); Hematoxylin & eosin stainings of samples in the study (S2); FACS ploidy histogram of Mm1702 (S3); Mutation-plots demonstrating the subclonality analysis in different regions of tumor Mm1641 (S4); Mutation-plots demonstrating the subclonality analysis in different regions of tumors Mm1641, Mm1702 and Mm1749 (S5); Mutation-plots demonstrating the subclonality analysis in different regions of tumor Mm1749 (S6); Mutation-plots demonstrating the subclonality analysis in different regions of tumors Mm1749, Mm1765 and Mm1767 (S7); Mutation-plots demonstrating the subclonality analysis in different regions of tumors Mm1767, Mm1772 and Mm1837 (S8); Correlations of trunk and non-trunk mutations to signatures from Alexandrov et al Nature 2013 (S9); Difference in expression levels between tumor regions harboring non-trunk mutations and those missing the corresponding mutations (S10); Correlation plots between DNA and RNA VAF in individual regions in tumors Mm1641 and Mm1702 (S11); Correlation plots between DNA and RNA VAF in individual regions in tumors Mm1702, Mm1742 and Mm1749 (S12); Correlation plots between DNA and RNA VAF in individual regions in tumors Mm1749 and Mm1765 (S13); Correlation plots between DNA and RNA VAF in individual regions in tumors Mm1767 and Mm1772 (S14); Correlation plots between DNA and RNA VAF in individual regions in tumor Mm1837 (S15).
159930_1_supp_0_d72rhn.doc from Multiregion Whole-Exome Sequencing Uncovers the Genetic Evolution and Mutational Heterogeneity of Early-Stage Metastatic Melanoma
Authors: Harbst Katja , Lauss Martin , Cirenajwis Helena , Isaksson Karolin , Rosengren Frida , Törngren Therese , Kvist Anders , Johansson Maria C. , Vallon-Christersson Johan , Baldetorp Bo , Borg Åke , Olsson Håkan , Ingvar Christian , Carneiro Ana , Jönsson Göran
Published: April 2023

159930_1_supp_0_d72rhn.doc from Multiregion Whole-Exome Sequencing Uncovers the Genetic Evolution and Mutational Heterogeneity of Early-Stage Metastatic Melanoma
Supplementary Table S1 from Oncogenic Functions of Gli1 in Pancreatic Adenocarcinoma Are Supported by Its PRMT1-Mediated Methylation
Authors: Wang Yan , Hsu Jung-Mao , Kang Ya'an , Wei Yongkun , Lee Pei-Chih , Chang Shing-Jyh , Hsu Yi-Hsin , Hsu Jennifer L. , Wang Hung-Ling , Chang Wei-Chao , Li Chia-Wei , Liao Hsin-Wei , Chang Shih-Shin , Xia Weiya , Ko How-Wen , Chou Chao-Kai , Fleming Jason B. , Wang Huamin , Hwang Rosa F. , Chen Yue , Qin Jun , Hung Mien-Chie
Published: April 2023

Gli1-binding proteins identified through mass spectrum.
Supplementary Table 5 from Landscape of Combination Immunotherapy and Targeted Therapy to Improve Cancer Management
Authors: Colli Leandro M. , Machiela Mitchell J. , Zhang Han , Myers Timothy A. , Jessop Lea , Delattre Olivier , Yu Kai , Chanock Stephen J.
Published: April 2023

Conditional logistic regression results for {greater than or equal to}192 NsM and gene mutations comparing Stage I and II to III and IV
Supplementary Table 4 from Landscape of Combination Immunotherapy and Targeted Therapy to Improve Cancer Management
Authors: Colli Leandro M. , Machiela Mitchell J. , Zhang Han , Myers Timothy A. , Jessop Lea , Delattre Olivier , Yu Kai , Chanock Stephen J.
Published: April 2023

Conditional logistic regression results for {greater than or equal to}192 NsM and gene mutations using ICGC and TP Samples
Supplementary Figures and Tables from NOTCH1 Signaling Regulates Self-Renewal and Platinum Chemoresistance of Cancer Stem–like Cells in Human Non–Small Cell Lung Cancer
Authors: Zhang Yun , Xu Wei , Guo Huiqin , Zhang Yanmei , He Yuexi , Lee Sau Har , Song Xin , Li Xiaoyan , Guo Yongqing , Zhao Yunlong , Ding Cheng , Ning Fei , Ma Yuanyuan , Lei Qun-Ying , Hu Xiaoyu , Li Shengnan , Guo Wei
Published: April 2023

This file contains 8 Supplementary Figures and 5 Supplementary Tables: Supplementary Figure S1 showed supplementary data regarding specimen processing and development of PD-SFA, which were related to Figure 1. Supplementary Figure S2 showed validation of the reported LCSC markers CD166 and CD133. Supplementary Figure S3 showed supplementary data regarding identification and characterization of novel LCSCs in vitro, which were related to Figure 4. Supplementary Figure S4 showed supplementary data regarding serial orthotopic xenograft assays to determine tumorigenic and self-renewal activity of LCSCs, which were related to Figure 4. Supplementary Figure S5 showed supplementary data regarding LCSC chemoresistance, which were related to Figure 5. Supplementary Figure S6 showed supplementary data regarding expression of stemness and LCSC-associated genes in LCSCs. Supplementary Figure S7 showed supplementary data regarding the role of NOTCH1 in LCSC self-renewal, which were related to Figure 6. Supplementary Figure S8 showed supplementary data regarding the role of NOTCH1 in LCSC platinum resistance, which were related to Figure 6. Supplementary Table S1 presented clinical information, mutational status, sphere-forming and LCSC frequencies associated with tumors. Supplementary Table S2 presented antibody information. Supplementary Table S3 presented RT-PCR primers. Supplementary Table S4 presented shRNA target sequences. Supplementary Table s5 presented primers for mutational analysis.
Supplementary Tables from Inhibiting Mitochondrial DNA Ligase IIIα Activates Caspase 1–Dependent Apoptosis in Cancer Cells
Authors: Sallmyr Annahita , Matsumoto Yoshihiro , Roginskaya Vera , Van Houten Bennett , Tomkinson Alan E.
Published: April 2023

Suppl. Table 1: IC50 values for the DNA Ligase inhibitor L67 for three cancer cells lines, a telomerase-immortalized fibroblast and the Rho minus derivatives of each of the cell lines; Suppl. Table 2: DNA sequences of primers used for amplification of specific fragments and nuclear and mitochondrial DNA using the polymerase chain reaction; Suppl. Table 3: Reaction conditions used to specific fragments and nuclear and mitochondrial DNA by the polymerase chain reaction
Supplementary Figure S2 from Preclinical Efficacy of the Auristatin-Based Antibody–Drug Conjugate BAY 1187982 for the Treatment of FGFR2-Positive Solid Tumors
Authors: Sommer Anette , Kopitz Charlotte , Schatz Christoph A. , Nising Carl F. , Mahlert Christoph , Lerchen Hans-Georg , Stelte-Ludwig Beatrix , Hammer Stefanie , Greven Simone , Schuhmacher Joachim , Braun Manuela , Zierz Ruprecht , Wittemer-Rump Sabine , Harrenga Axel , Dittmer Frank , Reetz Frank , Apeler Heiner , Jautelat Rolf , Huynh Hung , Ziegelbauer Karl , Kreft Bertolt
Published: April 2023

The anti-tumor efficacy of different FGFR2-ADC BAY 1187982 treatment schedules on MFM-223 human TNBC mouse model.
Supplementary Tables from Personalized Management of Pancreatic Ductal Adenocarcinoma Patients through Computational Modeling
Authors: Yamamoto Kimiyo N. , Yachida Shinichi , Nakamura Akira , Niida Atsushi , Oshima Minoru , De Subhajyoti , Rosati Lauren M. , Herman Joseph M. , Iacobuzio-Donahue Christine A. , Haeno Hiroshi
Published: April 2023

Supplementary Tables.Supplementary Table 1. Genetic alterations in CDKN2A, TP53, and SMAD4 drive metastasis in PDAC.Supplementary Table 2. Summary of Patient Cohorts.Supplementary Table 3. The concordance between immunohistochemistry and genetic sequencing in CDKN2A, TP53, and SMAD4 in PDAC.
Supplementary Table 1- Incidence of lung metastases in D2A1-d & parental D2A1 cells from Inflammation Triggers Zeb1-Dependent Escape from Tumor Latency
Authors: De Cock Jasmine M. , Shibue Tsukasa , Dongre Anushka , Keckesova Zuzana , Reinhardt Ferenc , Weinberg Robert A.
Published: April 2023

Summary of incidence of metastasis formation at limiting dilutions in D2A1-d and parental D2A1 cells
Supplementary Figure S4 from Metastatic Progression of Prostate Cancer Is Mediated by Autonomous Binding of Galectin-4-O-Glycan to Cancer Cells
Authors: Tsai Chin-Hsien , Tzeng Sheue-Fen , Chao Tai-Kuang , Tsai Chia-Yun , Yang Yu-Chih , Lee Ming-Ting , Hwang Jiuan-Jiuan , Chou Yu-Ching , Tsai Mong-Hsun , Cha Tai-Lung , Hsiao Pei-Wen
Published: April 2023

Galectin-4 expression regulates the induction of EMT-related genes and cell invasion in 22Rv1-M3 cells.
Supporting figures 1 through 7 and tables 1 through 3 from Targeting BRK-Positive Breast Cancers with Small-Molecule Kinase Inhibitors
Authors: Jiang Jie , Gui Fu , He Zhixiang , Li Li , Li Yunzhan , Li Shunying , Wu Xinrui , Deng Zhou , Sun Xihuan , Huang Xiaoxing , Huang Wei , Han Shang , Zhang Ting , Wang Zheng , Jiao Bo , Song Siyang , Wang Hongrui , Chen Lanfen , Zhou Dawang , Liu Qiang , Ren Ruibao , Zhang Jianming , Deng Xianming
Published: April 2023

Supplemental Figure S1. The chemical structure of compound 4f. Supplemental Figure S2, related to Figure 2. XMU-MP-2 induces apoptosis in BRK Ba/F3 cells without affecting the survival of the parental Ba/F3 cells. Supplemental Figure S3, related to Figure 3. XMU-MP-2 induces differential apoptosis in different BRK mutants transformed Ba/F3. Supplemental Figure S4, related to Figure 5. BRK knockdown inhibits the proliferation of BRK-positive breast cancer cell line BT-474. Supplemental Figure S5, related to Figure 5. Depletion of EGFR or HER2 didn't sufficiently attenuate the inhibitory activity of XMU-MP-2 in BT-474 cells. Supplemental Figure S6, related to Figure 6. XMU-MP-2 induces apoptosis in BRK and BRK Y447F-driven tumors in vivo. Supplemental Figure S7, related to Figure 6. XMU-MP-2 induces BRK- and BRK Y447F-driven tumor apoptosis. Supplemental Figure S8, related to Figure 6. The gatekeeper mutant T264M overrides the inhibition of XMU-MP-2 in the BRK T264M Ba/F3 xenograft model. Supplemental Figure S9, related to Figure 7. Profiling BRK expression in MCF7 and MCF7-TR cells. Table S1: IC50s of XMU-MP-2 on a panel of 28 Tyrosine Kinases transformed Ba/F3 cells. Table S2: Antiproliferative activity of XMU-MP-2 against a panel of human breast cancer and non-tumorigenic cell lines. Table S3: The list of primer sequences.
Supplementary tables. from Pancreatic Cancer Progression Relies upon Mutant p53-Induced Oncogenic Signaling Mediated by NOP14
Authors: Du Yongxing , Liu Ziwen , You Lei , Hou Pengjiao , Ren Xiaoxia , Jiao Tao , Zhao Wenjing , Li Zongze , Shu Hong , Liu Changzheng , Zhao Yupei
Published: April 2023

6 tables referenced in this manuscript is shown as supplementary files. Table S1. Characterization of 20 aired of PDAC patients. Table S2. Sequences of miRNAs and U6 snRNA primers. Table S3. Primer sequences of protein-coding genes. Table S4. NOP14 expression in primary PDAC and metastases. Table S5. Whole transcriptome RNA-sequencing data. Table S6. Comparison of NOP14 expression levels with clinico-pathological features in patients with pancreatic cancer.
Supplementary Figures from MCAM Mediates Chemoresistance in Small-Cell Lung Cancer via the PI3K/AKT/SOX2 Signaling Pathway
Authors: Tripathi Satyendra C. , Fahrmann Johannes F. , Celiktas Muge , Aguilar Mitzi , Marini Kieren D. , Jolly Mohit K. , Katayama Hiroyuki , Wang Hong , Murage Eunice N. , Dennison Jennifer B. , Watkins D. Neil , Levine Herbert , Ostrin Edwin J. , Taguchi Ayumu , Hanash Samir M.
Published: April 2023

Supplementary Figure 1: Increased MCAM expression in SCLC; Supplementary Figure 2: Chemoresistant cells showed mesenchymal like features; Supplementary Figure 3: MCAM knockdown in SCLC chemoresistant cells; Supplementary Figure 4; Effect of MCAM knockdown on chemoresistant cells; Supplementary Figure 5: Effect of MCAM overexpression in SCLC cells
Table S3. from Posttranscriptional Upregulation of IDH1 by HuR Establishes a Powerful Survival Phenotype in Pancreatic Cancer Cells
Authors: Zarei Mahsa , Lal Shruti , Parker Seth J. , Nevler Avinoam , Vaziri-Gohar Ali , Dukleska Katerina , Mambelli-Lisboa Nicole C. , Moffat Cynthia , Blanco Fernando F. , Chand Saswati N. , Jimbo Masaya , Cozzitorto Joseph A. , Jiang Wei , Yeo Charles J. , Londin Eric R. , Seifert Erin L. , Metallo Christian M. , Brody Jonathan R. , Winter Jordan M.
Published: April 2023

Table S3.FPKM values for all genes identified through RNA-sequencing
Supplementary Table S2 from Castration Resistance in Prostate Cancer Is Mediated by the Kinase NEK6
Authors: Choudhury Atish D. , Schinzel Anna C. , Cotter Maura B. , Lis Rosina T. , Labella Katherine , Lock Ying Jie , Izzo Francesca , Guney Isil , Bowden Michaela , Li Yvonne Y. , Patel Jinal , Hartman Emily , Carr Steven A. , Schenone Monica , Jaffe Jacob D. , Kantoff Philip W. , Hammerman Peter S. , Hahn William C.
Published: April 2023

AR staining of transgene-mediated androgen-independent LHSR-AR xenografts.
Supplementary Table S1 from Castration Resistance in Prostate Cancer Is Mediated by the Kinase NEK6
Authors: Choudhury Atish D. , Schinzel Anna C. , Cotter Maura B. , Lis Rosina T. , Labella Katherine , Lock Ying Jie , Izzo Francesca , Guney Isil , Bowden Michaela , Li Yvonne Y. , Patel Jinal , Hartman Emily , Carr Steven A. , Schenone Monica , Jaffe Jacob D. , Kantoff Philip W. , Hammerman Peter S. , Hahn William C.
Published: April 2023

Results of in vivo screen for genes conferring androgen independence, and of in vivo validation.
Supplementary Methods from Castration Resistance in Prostate Cancer Is Mediated by the Kinase NEK6
Authors: Choudhury Atish D. , Schinzel Anna C. , Cotter Maura B. , Lis Rosina T. , Labella Katherine , Lock Ying Jie , Izzo Francesca , Guney Isil , Bowden Michaela , Li Yvonne Y. , Patel Jinal , Hartman Emily , Carr Steven A. , Schenone Monica , Jaffe Jacob D. , Kantoff Philip W. , Hammerman Peter S. , Hahn William C.
Published: April 2023

Description of additional methods and procedures used in the study.
Supplementary Figure Legends from Dual Targeting of Insulin Receptor and KIT in Imatinib-Resistant Gastrointestinal Stromal Tumors
Authors: Chen Weicai , Kuang Ye , Qiu Hai-Bo , Cao Zhifa , Tu Yuqing , Sheng Qing , Eilers Grant , He Quan , Li Hai-Long , Zhu Meijun , Wang Yuexiang , Zhang Rongqing , Wu Yeqing , Meng Fanguo , Fletcher Jonathan A. , Ou Wen-Bin
Published: April 2023

This file contains legends for figures supplied as supplementary data. Immunoblot evaluations of EGFR and phospho-EGFR in GIST cell lines and non-small cell lung cancer cell lines (A549 and PC-9). Actin stain is a loading control. Coordinated inhibition of IR and KIT has additive effect on cell viability in imatinib-resistant GIST430, as compared to either intervention alone, but not in imatinib-sensitive GIST882.
Supplementary material from Exercise-Induced Catecholamines Activate the Hippo Tumor Suppressor Pathway to Reduce Risks of Breast Cancer Development
Authors: Dethlefsen Christine , Hansen Louise S. , Lillelund Christian , Andersen Christina , Gehl Julie , Christensen Jesper F. , Pedersen Bente K. , Hojman Pernille
Published: April 2023

Supplementery method section describing the standard molecular methods, as well as 5 supplementary figures, including Fig. S1 on exercise response in helathy women, Fig. S2 on breast cancer cell viability after stimulation with epinephrine/norepinphrine, Fig. S3 on Hippo signaling after stimulation with epinephrine/norepinehprine, Fig. S4 on Hippo signaling after stimulation with exercise-conditioned serum, and Fig. S5 on the effect on wheel running of physiological adaptations.
Figure S5 from Nicotinic Acid Phosphoribosyltransferase Regulates Cancer Cell Metabolism, Susceptibility to NAMPT Inhibitors, and DNA Repair
Authors: Piacente Francesco , Caffa Irene , Ravera Silvia , Sociali Giovanna , Passalacqua Mario , Vellone Valerio G. , Becherini Pamela , Reverberi Daniele , Monacelli Fiammetta , Ballestrero Alberto , Odetti Patrizio , Cagnetta Antonia , Cea Michele , Nahimana Aimable , Duchosal Michel , Bruzzone Santina , Nencioni Alessio
Published: April 2023

Figure S5 shows that 2-HNA inhibits NAPRT enzymatic activity and increases glycolysis in OVCAR-5 cells.
Figure S2 from Nicotinic Acid Phosphoribosyltransferase Regulates Cancer Cell Metabolism, Susceptibility to NAMPT Inhibitors, and DNA Repair
Authors: Piacente Francesco , Caffa Irene , Ravera Silvia , Sociali Giovanna , Passalacqua Mario , Vellone Valerio G. , Becherini Pamela , Reverberi Daniele , Monacelli Fiammetta , Ballestrero Alberto , Odetti Patrizio , Cagnetta Antonia , Cea Michele , Nahimana Aimable , Duchosal Michel , Bruzzone Santina , Nencioni Alessio
Published: April 2023

Figure S2 shows that NAPRT silencing does not induce compensatory NAMPT upregulation in cancer cells.
Supplementary Figures from Super-Enhancers Promote Transcriptional Dysregulation in Nasopharyngeal Carcinoma
Authors: Yuan Jiang , Jiang Yan-Yi , Mayakonda Anand , Huang Moli , Ding Ling-Wen , Lin Han , Yu Fenggang , Lu Yanan , Loh Thomas Kwok Seng , Chow Marilynn , Savage Samantha , Tyner Jeffrey W. , Lin De-Chen , Koeffler H. Phillip
Published: April 2023

Supplementary Figure 1. Distribution of putative targets of the top-ranked small molecules Supplementary Figure 2. CDK7 silencing significantly inhibited cells growth Supplementary Figure 3. Cell viability assay of C666-1 cells treated with THZ1 Supplementary Figure 4. Cell-cycle arrested at G2/M stage in C666-1 and HK1 cells treated with THZ1 Supplementary Figure 5. Cell viability (A) and apoptosis assay (B) showing the effects of THZ1 treatment in PNHNC Supplementary Figure 6. THZ1 potently suppressed xenografts growth and lung metastasis of NPC cells in NOD/SCID mice Supplementary Figure 7. THZ1 exhibited prominent anti-NPC activity in NOD/SCID mice Supplementary Figure 8. THZ1 inhibited RNAPII-mediated transcription in NPC Supplementary Figure 9. Representative SE-associated genes in NPC and PNHNC Supplementary Figure 10. Gene Ontology enrichment analysis of SE-associated genes in PNHNC cell
Supplmental Figures and Legends from ATOH1 Promotes Leptomeningeal Dissemination and Metastasis of Sonic Hedgehog Subgroup Medulloblastomas
Authors: Grausam Katie B. , Dooyema Samuel D.R. , Bihannic Laure , Premathilake Hasitha , Morrissy A. Sorana , Forget Antoine , Schaefer Amanda M. , Gundelach Justin H. , Macura Slobodan , Maher Diane M. , Wang Xin , Heglin Alex H. , Ge Xijin , Zeng Erliang , Puget Stephanie , Chandrasekar Indra , Surendran Kameswaran , Bram Richard J. , Schüller Ulrich , Talyor Michael D. , Ayrault Olivier , Zhao Haotian
Published: April 2023

This file provides illustration of supplemental experimental results and explanation of data presented. Supplemental Figure 1 Analysis of gene expression in CAG-A1Z transgenic mice. Supplemental Figure 2 Normal cerebellar development in Atoh1 transgenic animals. Supplemental Figure 3 Atoh1 over-expression enhances MB development and metastasis along the spinal cord in Ptch1+/- mice. Supplemental Figure 4 ATOH1-driven MB development and metastasis. Supplemental Figure 5 Analysis of gene expression in SHH MB from different mouse strains. Supplemental Figure 6 ATOH1-driven development and metastasis in AAP and LAP mice. Supplemental Figure 7 Analysis of gene expression in human MB. Supplemental Figure 8 Analysis of gene expression in MB from MAP animals.
Supplemental table 3 from ATOH1 Promotes Leptomeningeal Dissemination and Metastasis of Sonic Hedgehog Subgroup Medulloblastomas
Authors: Grausam Katie B. , Dooyema Samuel D.R. , Bihannic Laure , Premathilake Hasitha , Morrissy A. Sorana , Forget Antoine , Schaefer Amanda M. , Gundelach Justin H. , Macura Slobodan , Maher Diane M. , Wang Xin , Heglin Alex H. , Ge Xijin , Zeng Erliang , Puget Stephanie , Chandrasekar Indra , Surendran Kameswaran , Bram Richard J. , Schüller Ulrich , Talyor Michael D. , Ayrault Olivier , Zhao Haotian
Published: April 2023

This table provide supplemental information on the results of ChIP-seq and gene expression analyses of primary and spinal metastatic tumors in MAP mice.
Supplemental Table 2: Copy level of interstitial genes from Retention of Interstitial Genes between TMPRSS2 and ERG Is Associated with Low-Risk Prostate Cancer
Authors: Murphy Stephen J. , Kosari Farhad , Karnes R. Jeffrey , Nasir Aqsa , Johnson Sarah H. , Gaitatzes Athanasios G. , Smadbeck James B. , Rangel Laureano J. , Vasmatzis George , Cheville John C.
Published: April 2023

Coverage level for each gene located between TMPRSS2 and ERG.
Supplemental Figures 2 to 4 from Retention of Interstitial Genes between TMPRSS2 and ERG Is Associated with Low-Risk Prostate Cancer
Authors: Murphy Stephen J. , Kosari Farhad , Karnes R. Jeffrey , Nasir Aqsa , Johnson Sarah H. , Gaitatzes Athanasios G. , Smadbeck James B. , Rangel Laureano J. , Vasmatzis George , Cheville John C.
Published: April 2023

Supplemental Figure 2 presents genome coverage plots for four example cases illustrating complex rearrangements between chromosomes (A-D) plus a schematic of the complex TMPRSS2-ERG rearrangement in PR084. Supplemental Figure 3 illustrates the number of breakpoints from genomic rearrangements hitting chromosome 21q. Supplemental Figure 4 illustrates survival analysis from data from Fraser et al 2017 comparing non-indolent prostate cancers with TMPRSS2-ERG fusions with interstitial deletion or retention.
Supplemental Figure 2 from KLF6 Suppresses Metastasis of Clear Cell Renal Cell Carcinoma via Transcriptional Repression of E2F1
Authors: Gao Yu , Li Hongzhao , Ma Xin , Fan Yang , Ni Dong , Zhang Yu , Huang Qingbo , Liu Kan , Li Xintao , Wang Lei , Gu Liangyou , Yao Yuanxin , Ai Qing , Du Qingshan , Song Erlin , Zhang Xu
Published: April 2023

The ranking ï¬,ow chart of the differentiated genes on the data set
Supplementary Figure S1. from Cancer-Associated Fibroblasts Share Characteristics and Protumorigenic Activity with Mesenchymal Stromal Cells
Authors: Borriello Lucia , Nakata Rie , Sheard Michael A. , Fernandez G. Esteban , Sposto Richard , Malvar Jemily , Blavier Laurence , Shimada Hiroyuki , Asgharzadeh Shahab , Seeger Robert C. , DeClerck Yves A.
Published: April 2023

Characterization of CAF-MSC and BM-MSC isolated from different patients.