bluuebunny/crossref_metadata_2025 huggingface dataset:
A Study on Optimal Compensation Design for Meteorological Satellites in the Presence of Periodic Disturbance
Authors: Xu Shijie , Cui Naigang , Fan Youhua , Guan Yingzi
Published: July 2018

Periodic disturbance may cause serious effects on the attitude of meteorological satellites, and the attenuation of periodic disturbance is required. In this paper, a fundamental study on the optimal design of constant compensations against known-law periodic disturbance for meteorological satellites is investigated. An analytical solution for the relationship between the frequency and amplitude ratios and the response of a typical second-order vibration system is firstly derived. The compensation and disturbance torques are determined according to practical engineering. The criteria for designing the optimal compensations are based on the analytical and simulation results. Then, the criteria are applied to a flexible spacecraft actuated by constant control torque in the presence of sustained periodic disturbance. The optimal compensation torque parameters for spacecraft are acquired based on former criteria. The compensate effectiveness of the optimal compensation torque is provided and compared with results of other selections in the frequency and amplitude ratio domain. Numerical simulation results and experimental results clearly demonstrate the good performance of proposed criteria. This work provides a significant reference for the vibration attenuation of meteorological satellites in the present of periodic disturbance.
Using Adverse Weather Data in Social Media to Assist with City-Level Traffic Situation Awareness and Alerting
Authors: Lu Hao , Zhu Yifan , Shi Kaize , Lv Yisheng , Shi Pengfei , Niu Zhendong
Published: July 2018

Traffic situation awareness and alerting assisted by adverse weather conditions contributes to improve traffic safety, disaster coping mechanisms, and route planning for government agencies, business sectors, and individual travelers. However, at the city level, the physical sensor-generated data are partly held by different transportation and meteorological departments, which causes problems of “isolated information” for data fusion. Furthermore, it makes traffic situation awareness and estimation challenging and ineffective. In this paper, we leverage the power of crowdsourcing knowledge in social media and propose a novel way to forecast and generate alerts for city-level traffic incidents based on a social approach rather than traditional physical approaches. Specifically, we first collect adverse weather topics and reports of traffic incidents from social media. Then, we extract temporal, spatial, and meteorological features as well as labeled traffic reaction values corresponding to the social media “heat” for each city. Afterwards, the regression and alerting model is proposed to estimate the city-level traffic situation and give the suggestion of warning levels. The experiments show that the proposed model equipped with gcForest achieves the best root mean square error (RMSE) and mean absolute percentage error (MAPE) score on the social traffic incidents test dataset. Moreover, we consider the news report as an objective measurement to flexibly validate the feasibility of proposed model from social cyberspace to physical space. Finally, a prototype system was deployed and applied to government agencies to provide an intuitive visualization solution as well as decision support assistance.
Development and Application of a Hot-Dry-Windy Index (HDW) Climatology
Authors: McDonald Jessica M. , Srock Alan F. , Charney Joseph J.
Published: July 2018

In this paper, we describe and analyze a climatology of the Hot-Dry-Windy Index (HDW), with the goal of providing fire-weather forecasters with information about the daily and seasonal variability of the index. The 30-year climatology (1981–2010) was produced using the Climate Forecast System Reanalysis (CFSR) for the contiguous United States, using percentiles to show seasonal and geographical variations of HDW contained within the climatology. The method for producing this climatology is documented and the application of the climatology to historical fire events is discussed. We show that the HDW climatology provides insight into near-surface climatic conditions that can be used to identify temperature and humidity trends that correspond to climate classification systems. Furthermore, when used in conjunction with daily traces of HDW values, users can follow trends in HDW and compare those trends with historical values at a given location. More usefully, this climatology adds value to HDW forecasts; by combining the CFSR climatology and a Global Ensemble Forecast System (GEFS) ensemble history and forecast, we can produce a single product that provides seasonal, climatological, and short-term context to help determine the appropriate fire-management response to a given HDW value.
The Efficacy of Transcranial Current Stimulation Techniques to Modulate Resting-State EEG, to Affect Vigilance and to Promote Sleepiness
Authors: Annarumma Ludovica , D’Atri Aurora , Alfonsi Valentina , De Gennaro Luigi
Published: July 2018

Transcranial Current Stimulations (tCSs) are non-invasive brain stimulation techniques which modulate cortical excitability and spontaneous brain activity by the application of weak electric currents through the scalp, in a safe, economic, and well-tolerated manner. The direction of the cortical effects mainly depend on the polarity and the waveform of the applied current. The aim of the present work is to provide a broad overview of recent studies in which tCS has been applied to modulate sleepiness, sleep, and vigilance, evaluating the efficacy of different stimulation techniques and protocols. In recent years, there has been renewed interest in these stimulations and their ability to affect arousal and sleep dynamics. Furthermore, we critically review works that, by means of stimulating sleep/vigilance patterns, in the sense of enhancing or disrupting them, intended to ameliorate several clinical conditions. The examined literature shows the efficacy of tCSs in modulating sleep and arousal pattern, likely acting on the top-down pathway of sleep regulation. Finally, we discuss the potential application in clinical settings of this neuromodulatory technique as a therapeutic tool for pathological conditions characterized by alterations in sleep and arousal domains and for sleep disorders per se.
Clarification of Active Sites at Interfaces between Silica Support and Nickel Active Components for Carbon Monoxide Methanation
Authors: Zhang Mengjuan , Li Panpan , Tian Zhiqun , Zhu Mingyuan , Wang Fu , Li Jiangbing , Dai Bin , Yu Feng , Qiu Hengshan , Gao Hongwei
Published: July 2018

Identification of active site is critical for developing advanced heterogeneous catalysis. Here, a nickel/silica (Ni/SiO2) catalyst was prepared through an ammonia-evaporation method for CO methanation. The as-obtained Ni/SiO2 catalyst shows a CO conversion of 96.74% and a methane selectivity of 93.58% at 623 K with a weight hourly space velocity of 25,000 mL·g−1·h−1. After 150 h of continuous testing, the CO conversion still retains 96%, which indicates a high catalyst stability and long life. An in situ vacuum transmission infrared spectrum demonstrates that the main active sites locate at the interface between the metal Ni and the SiO2 at a wave number at 2060 cm−1 for the first time. The interesting discovery of the active site may offer a new insight for design and synthesis of methanation catalysts.
Pediatric Intestinal Failure Review
Authors: Mangalat Nisha , Teckman Jeffrey
Published: July 2018

The term, ‘intestinal failure’, signifies the inability of the body to meet the digestive, absorptive and nutritive needs of the body. As such, these individuals require parenteral nutrition (PN) for survival. The subsequent nutritional, medical and surgical facets to the care are complex. Improved care has resulted in decreased need for intestinal transplantation. This review will examine the unique etiologies and management strategies in pediatric patients with intestinal failure.
Molecular Synchronization Enhances Molecular Interactions: An Explanatory Note of Pressure Effects
Authors: Numata Munenori , Kanzaki Chisako
Published: July 2018

In this study, we investigated a unique aspect of the supramolecular polymerization of tetrakis (4-sulfonatophenyl) porphyrin (TPPS), a self-assembling porphyrin, under non-equilibrium conditions by subtracting the effects of back-pressure on its polymerization. We focused on the enhanced self-assembly abilities of TPPS under a process of rapid proton diffusion in a microflow channel. Rapid protonation caused synchronization of many sets of protonation/deprotonation equilibria on the molecular scale, leading to the production of many sets of growing suparmolecular spices. Pressure effects in the microflow channel, which could potentially promote self-assembly of TPPS, were negligible, becoming predominant only when the system was in the synchronized state.
Turbulence through the Spyglass of Bilocal Kinetics
Authors: Chliamovitch Gregor , Thorimbert Yann
Published: July 2018

In two recent papers we introduced a generalization of Boltzmann’s assumption of molecular chaos based on a criterion of maximum entropy, which allowed setting up a bilocal version of Boltzmann’s kinetic equation. The present paper aims to investigate how the essentially non-local character of turbulent flows can be addressed through this bilocal kinetic description, instead of the more standard approach through the local Euler/Navier–Stokes equation. Balance equations appropriate to this kinetic scheme are derived and closed so as to provide bilocal hydrodynamical equations at the non-viscous order. These equations essentially consist of two copies of the usual local equations, but coupled through a bilocal pressure tensor. Interestingly, our formalism automatically produces a closed transport equation for this coupling term.
Response to Noise Emitted by Wind Farms in People Living in Nearby Areas
Authors: Pawlaczyk-Łuszczyńska Małgorzata , Zaborowski Kamil , Dudarewicz Adam , Zamojska-Daniszewska Małgorzata , Waszkowska Małgorzata
Published: July 2018

The aim of this study was to evaluate the perception and annoyance of noise from wind turbines in populated areas of Poland. A questionnaire inquiry was carried out among 517 subjects, aged 18–88, living within 204–1726 m from the nearest wind turbine. For areas where respondents lived, A-weighted sound pressure levels (SPLs) were calculated as the sum of the contributions from the wind power plants in the specific area. It has been shown that the wind turbine noise at the calculated A-weighted SPL of 33–50 dB was perceived as annoying or highly annoying by 46% and 28% of respondents, respectively. Moreover, 34% and 18% of them said that they were annoyed or highly annoyed indoors, respectively. The perception of high annoyance was associated with the A-weighted sound pressure level or the distance from the nearest wind turbine, general attitude to wind farms, noise sensitivity and terrain shape (annoyance outdoors) or road-traffic intensity (annoyance indoors). About 48–66% of variance in noise annoyance rating might be explained by the aforesaid factors. It was estimated that at the distance of 1000 m the wind turbine noise might be perceived as highly annoying outdoors by 43% and 2% of people with negative and positive attitude towards wind turbines, respectively. There was no significant association between noise level (or distance) and various health and well-being aspects. However, all variables measuring health and well-being aspects, including stress symptoms, were positively associated with annoyance related to wind turbine noise.
Functional Characterization and Structure-Guided Mutational Analysis of the Transsulfuration Enzyme Cystathionine γ-Lyase from Toxoplasma gondii
Authors: Maresi Elena , Janson Giacomo , Fruncillo Silvia , Paiardini Alessandro , Vallone Rosario , Dominici Paola , Astegno Alessandra
Published: July 2018

Sulfur-containing amino acids play essential roles in many organisms. The protozoan parasite Toxoplasma gondii includes the genes for cystathionine β-synthase and cystathionine γ-lyase (TgCGL), as well as for cysteine synthase, which are crucial enzymes of the transsulfuration and de novo pathways for cysteine biosynthesis, respectively. These enzymes are specifically expressed in the oocyst stage of T. gondii. However, their functionality has not been investigated. Herein, we expressed and characterized the putative CGL from T. gondii. Recombinant TgCGL almost exclusively catalyses the α,γ-hydrolysis of l-cystathionine to form l-cysteine and displays marginal reactivity toward l-cysteine. Structure-guided homology modelling revealed two striking amino acid differences between the human and parasite CGL active-sites (Glu59 and Ser340 in human to Ser77 and Asn360 in toxoplasma). Mutation of Asn360 to Ser demonstrated the importance of this residue in modulating the specificity for the catalysis of α,β- versus α,γ-elimination of l-cystathionine. Replacement of Ser77 by Glu completely abolished activity towards l-cystathionine. Our results suggest that CGL is an important functional enzyme in T. gondii, likely implying that the reverse transsulfuration pathway is operative in the parasite; we also probed the roles of active-site architecture and substrate binding conformations as determinants of reaction specificity in transsulfuration enzymes.
An Efficient Task Autonomous Planning Method for Small Satellites
Authors: Long Jun , Li Cong , Zhu Lei , Chen Shilong , Liu Junfeng
Published: July 2018

Existing on-board planning systems do not apply to small satellites with limited onboard computer capacity and on-board resources. This study aims to investigate the problem of autonomous task planning for small satellites. Based on the analysis of the problem and its constraints, a model of task autonomous planning was implemented. According to the long-cycle task planning requirements, a framework of rolling planning was proposed, including a rolling window and planning unit in the solution, and we proposed an improved genetic algorithm (IGA) for rolling planning. This algorithm categorized each individual based on the compliance of individuals with a time partial order constraint and resource constraint, and designed an appropriate crossover operator and mutation operator for each type of individual. The experimental result showed that the framework and algorithm can not only respond quickly to observation tasks, but can produce effective planning programs to ensure the successful completion of observation tasks.
A Modified Catenary Model with Application to the Analysis and Design of Retrofit Cables for Progressive Collapse
Authors: Deputy Leven T. , Zeinali Yasha , Story Brett A.
Published: July 2018

Progressive collapse, the extensive or complete collapse of a structure resulting from the failure of one or a small number of structural components, has become a focus of research efforts and design considerations following events occurring at the Ronan Point apartment building in London, the Murrah Federal Building in Oklahoma City, and the World Trade Center in New York City. A principle research and design area for progressive collapse investigates the behavior of structural frames when column support is removed. The mechanism that results from loss of column support in structural frames characteristically involves beams that are unable to provide sufficient flexural resistance. Cable retrofit is one method to enhance existing frames and supplement or replace the post-mechanism beam load resistance with straight-legged catenary resistance after a column removal. The cables are located linearly along the beam geometry and are affixed at beam supports. This paper investigates both static and dynamic behavior of the catenary action of retrofit cables, which include both the linear and nonlinear material behavior of the cable material. Moreover, a simplified model serves as the basis for retrofit cable design is presented. Finite element modeling and experimentation in this paper verify and validate the applicability of the model. Finally, a framework for developing a procedure for retrofit cable design is presented.
Research on Grain Refinement Mechanism of 6061 Aluminum Alloy Processed by Combined SPD Methods of ECAP and MAC
Authors: Zhang Zhenwei , Wang Junli , Zhang Qinglong , Zhang Supeng , Shi Qingnan , Qi Huarong
Published: July 2018

Equal channel angular pressing (ECAP) and multi-axial compression deformation (MAC) are severe plastic deformation (SPD) processes that produce bulk nanostructured materials with ultrafine grains. The grains could be observably refined by multi-pass of ECAP and MAC. This research proposed new routes of cyclic equal channel compression (CECC), which combines ECAP and MAC to increase the mechanical properties of 6061 aluminum alloy. The tests, which are conducted through electron backscattered diffraction (EBSD) and transmission electron microscope (TEM), were performed on the grain size, recrystallization distribution, misorientation distributions, dislocations, and secondary phase distributions of CECC-processed 6061 aluminum alloys on the purpose of exploring the mechanism of grain refinement. MEM is the short form for the CECC processing route of MAC + ECAP + MAC, which is one ECAP pass between two MAC passes. The tests results showed that the average grain size could reach to as much as 1.1 μm after two MEM deformation circles named MEM-MEM, with the non-annealing average grain size being 21 μm and recrystallization annealed average grain size being 28 μm. The dislocation cells, which could be transformed into sub-grains with the increase of the strain, were formed by the slip and the accumulation of dislocations. The secondary phase was Mg2Si, which could prevent the refined grains from growing up again by pinning at the grain boundaries. Above all, the dislocation proliferation and secondary phases will both lead to the grain refinement.
The Phase Evolution and Physical Properties of Binary Copper Oxide Thin Films Prepared by Reactive Magnetron Sputtering
Authors: Zheng Weifeng , Chen Yue , Peng Xihong , Zhong Kehua , Lin Yingbin , Huang Zhigao
Published: July 2018

P-type binary copper oxide semiconductor films for various O2 flow rates and total pressures (Pt) were prepared using the reactive magnetron sputtering method. Their morphologies and structures were detected by X-ray diffraction, Raman spectrometry, and SEM. A phase diagram with Cu2O, Cu4O3, CuO, and their mixture was established. Moreover, based on Kelvin Probe Force Microscopy (KPFM) and conductive AFM (C-AFM), by measuring the contact potential difference (VCPD) and the field emission property, the work function and the carrier concentration were obtained, which can be used to distinguish the different types of copper oxide states. The band gaps of the Cu2O, Cu4O3, and CuO thin films were observed to be (2.51 ± 0.02) eV, (1.65 ± 0.1) eV, and (1.42 ± 0.01) eV, respectively. The resistivities of Cu2O, Cu4O3, and CuO thin films are (3.7 ± 0.3) × 103 Ω·cm, (1.1 ± 0.3) × 103 Ω·cm, and (1.6 ± 6) × 101 Ω·cm, respectively. All the measured results above are consistent.
Speciation of Ruthenium(III) Chloro Complexes in Hydrochloric Acid Solutions and Their Extraction Characteristics with an Amide-Containing Amine Compound
Authors: Suzuki Tomoya , Ogata Takeshi , Tanaka Mikiya , Kobayashi Tohru , Shiwaku Hideaki , Yaita Tsuyoshi , Narita Hirokazu
Published: July 2018

The refining of platinum group metals is based mainly on solvent extraction methods, whereas Ru is selectively recovered by distillation as RuO4. Replacement of distillation by extraction is expected to simplify the purification process. To develop an effective extraction system for Ru, we analyzed the Ru species in HCl with ultraviolet-visible (UV-Vis) and Ru K-edge extended X-ray absorption fine structure (EXAFS) spectroscopies, and we examined the properties of Ru extracted with N-2-ethylhexyl-bis(N-di-2-ethylhexyl-ethylamide) amine (EHBAA) and trioctylamine (TOA). EXAFS and UV-Vis spectra of Ru in HCl solutions revealed that the predominant Ru species in 0.5–10 M HCl solutions changed from [RuCl4(H2O)2]− to [RuCl6]3− with the HCl concentration. The extraction percentages (E%) of Ru in the EHBAA system increased with increasing HCl concentration, reached 80% at [HCl] = 5 M, and decreased at higher HCl concentrations; the corresponding E% for TOA were low. EXAFS analysis of the extracted complex indicated that the Ru3+ had 5 Cl− and 1 H2O in its inner coordination sphere. The similarity of the dependence on HCl concentrations of the E% in the EHBAA system and the distribution profile of [RuCl5(H2O)]2− on [RuCln(H2O)6−n]3−n suggested that the EHBAA extracted the pentachlorido species.
Strain Rate Dependence of Material Strength in AA5xxx Series Aluminum Alloys and Evaluation of Their Constitutive Equation
Authors: Yamada Hiroyuki , Kami Tsuyoshi , Mori Ryota , Kudo Tomoyuki , Okada Minemitsu
Published: July 2018

The effect of strain rate on the mechanical properties of AA5xxx series aluminum alloys containing solute Mg atoms (AA5005, AA5021, AA5082 and AA5182) and pure aluminum (A1070) was investigated within a wide strain rate range of 1.0 × 10−4 to 1.0 × 103 s−1 at room temperature. The A1070 exhibited a positive strain rate dependence of material strength at the investigated strain rates. However, the AA5xxx series aluminum alloys primarily exhibited the negative strain rate dependence of material strength and serration caused by the Portevin-Le Chatelier effect on the Mg content and strain rate. As a result of using the material constitutive equation for the negative strain rate dependence, it was found that the flow stress may change in the dynamic strain rate range. However, it was found that the strain rate dependence of material strength differed in the AA5082 and the AA5182 alloys. It would be caused by less solute Mg of the Al phase in the AA5182 alloy than in the AA5082 alloy, because more Mg2Si compounds precipitated on Mn bearing particles as precipitation sites in the AA5182 alloy.
Interaction Mechanism between Molybdenite and Kaolinite in Gypsum Solution Using Kerosene as the Flotation Collector
Authors: Sun Liqing , Cao Yijun , Liao Yinfei , Ma Zilong
Published: July 2018

This paper aims to understand the fundamental interaction mechanism between molybdenite and kaolinite in gypsum solution using kerosene as collector. Micro-flotation tests were conducted to study the effect of gypsum solution on the flotation performance of mixed −74 μm molybdenite and −10 μm kaolinite mineral. The results showed that the recovery of molybdenite decreased from 86% to 74% while the gypsum solution concentration increased from 0 to 800 mg/L, indicating the detrimental effect of kaolinite on molybdenite flotation could be enhanced by gypsum solution. This is mainly caused by the slime coating of kaolinite on molybdenite through dissolved calcium ion of gypsum solution. In order to confirm the slime coating phenomenon, zeta potential distribution, scanning electron microscopy (SEM) and atomic force microscopy (AFM) measurements were used to investigate interaction characteristics and mechanisms. The zeta potential distribution results revealed that mixed samples had the value between signal molybdenite and kaolinite samples in gypsum solution, which proved the coating phenomenon of kaolinite on molybdenite. Moreover, the coating phenomenon was becoming more and more obvious with the gypsum solution concentration. The coating phenomenon of kaolinite on molybdenite surface was also directly observed from SEM results. The AFM results provided further evidence for the possibility of slime coating, as the adhesion force increased with the gypsum solution concentration, which means the aggregates of molybdenite and kaolinite were becoming more stable.
What the Diffuse Layer (DL) Reveals in Non-Linear SFG Spectroscopy
Authors: Pezzotti Simone , Galimberti Daria , Shen Y. , Gaigeot Marie-Pierre
Published: July 2018

Following our recent work [Phys. Chem. Chem. Phys. 20:5190–99 (2018)] that provided the means to unambigously define and extract the three water regions at any charged interface (solid–liquid and air–liquid alike), denoted the BIL (Binding Interfacial Layer), DL (Diffuse Layer) and Bulk, and how to calculate their associated non-linear Sum Frequency Generation Spectroscopy (SFG) χ2(ω) spectroscopic contributions from Density Functional Theory (DFT)-based ab initio molecular dynamics simulations (DFT-MD/AIMD), we show here that the χDL2(ω) signal arising from the DL water region carries a wealth of essential information on the microscopic and macroscopic properties of interfaces. We show that the χDL2(ω) signal carries information on the surface potential and surface charge, the isoelectric point, EDL (Electric Double Layer) formation, and the relationship between a nominal electrolyte solution pH and surface hydroxylation state. This work is based on DFT-MD/AIMD simulations on a (0001) α–quartz–water interface and on the air–water interface, with various surface quartz hydroxylation states and various electrolyte concentrations. The conclusions drawn make use of the interplay between experiments and simulations. Most of the properties listed above can now be extracted from experimental χDL2(ω) alone with the protocols given in this work, or by making use of the interplay between experiments and simulations, as described in this work.
Physicochemical Properties of Lutein-Loaded Microcapsules and Their Uptake via Caco-2 Monolayers
Authors: Zhao Tong , Liu Fuguo , Duan Xiang , Xiao Chunxia , Liu Xuebo
Published: July 2018

Lutein is one of the most important carotenoids that can be utilized in foods as a natural pigment and nutraceutical ingredient to improve eye health. However, its utilization is limited due to its poor solubility. Chemically, the highly unsaturated structure of lutein makes it extremely susceptible to light, oxygen, heat, and pro-oxidants and therefore easily oxidized, decomposed or dissociated. In this study, we aimed to imbed natural lutein to improve its storage stability and enhance its water dispersibility. As two commonly studied water-soluble and water-insoluble food-grade surfactants, sodium caseinate (NaCas) and lecithin were chosen as the wall materials, and lutein-loaded lecithin microcapsules and NaCas microcapsules were prepared, the results revealed the lutein-loaded NaCas microcapsules not only exhibited better dispersibility and stability than those of lutein-loaded lecithin microcapsules, but also were more stable when stored at 4 °C, 25 °C, 37 °C. Moreover, the lutein-loaded NaCas microcapsules were more easily absorbed by the intestinal Caco-2 cells than natural lutein. Considering the dispersibility, stability and cell absorption effect, the NaCas-based microparticle is a potential carrier for lutein.
Adherence to the Mediterranean Diet and Serum Adiponectin Levels in Pregnancy: Results from a Cohort Study in Normal Weight Caucasian Women
Authors: Spadafranca Angela , Piuri Gabriele , Bulfoni Camilla , Liguori Isabel , Battezzati Alberto , Bertoli Simona , Speciani Attilio F. , Ferrazzi Enrico
Published: July 2018

The Mediterranean Diet (MedDiet) is significantly associated with anti-inflammatory effects and a favorable health outcome. During pregnancy, both inflammatory changes and oxidative balance are essential for a successful outcome, while an unbalanced inflammatory response can be a key mediator of obstetrical syndromes. The aim of this study is to investigate the adherence to MedDiet during pregnancy in the 1st and in the 3rd trimester, and to test whether the adherence was associated with serum adiponectin levels. The study was carried out on 99 normal weight Caucasian women. The adherence to MedDiet was measured by a 13-point Mediterranean scale. The whole sample scored 7.2 ± 1.5, with no difference between first and third trimester (p = 0.7). Critical points were: fruit < 3 servings/day in 77% of the sample, beans < 3 times/week in 89%, fish < 2 times/week in 69%, and nut weekly intake < 30 g in 75%. The serum adiponectin levels significantly decreased from the first to the third trimester (−16% ± 4%, p = 0.008), which confirms a low-grade inflammatory condition associated with advancing gestational age. The women who were in the highest tertile of the adherence to MedDiet had a lower percentage decrease, as compared with those in the lowest tertile (10% ± 11% vs. −34% ± 3%, p = 0.01). Even if in pregnancy the adiponectin levels are strongly influenced by the low-grade inflammation, the adherence to MedDiet may modulate this state.
Polygonum multiflorum Extract Exerts Antioxidative Effects and Increases Life Span and Stress Resistance in the Model Organism Caenorhabditis elegans via DAF-16 and SIR-2.1
Authors: Saier Christina , Büchter Christian , Koch Karoline , Wätjen Wim
Published: July 2018

Extracts of the Chinese plant Polygonum multiflorum (PME) are used for medicinal purposes as well as food supplement due to anti-aging effects. Despite of the common use of these food supplements, experimental data on physiological effects of PME and its underlying molecular mechanisms in vivo are limited. We used the model organism Caenorhabditis elegans to analyze anti-aging-effects of PME in vivo (life span, lipofuscin accumulation, oxidative stress resistance, thermal stress resistance) as well as the molecular signaling pathways involved. The effects of PME were examined in wildtype animals and mutants defective in the sirtuin-homologue SIR-2.1 (VC199) and the FOXO-homologue DAF-16 (CF1038). PME possesses antioxidative effects in vivo and increases oxidative stress resistance of the nematodes. While the accumulation of lipofuscin is only slightly decreased, PME causes a significant elongation (18.6%) of mean life span. DAF-16 is essential for the reduction of thermally induced ROS accumulation, while the resistance against paraquat-induced oxidative stress is dependent on SIR-2.1. For the extension of the life span, both DAF-16 and SIR-2.1 are needed. We demonstrate that PME exerts protective effects in C. elegans via modulation of distinct intracellular pathways.
Exploring Touch in Physical Education Practicum in a Touchy Latin Culture
Authors: Varea Valeria , González-Calvo Gustavo , Martínez-Álvarez Lucio
Published: July 2018

The decrease in touch has been explored in recent literature in relation to child protection discourses and no touch policies and it has been suggested that Physical Education (PE) has been weakened by the lack of touch. Significantly, the issue of touch has remained largely unexplored in Latin societies, which are characterised by an amplified tactile approach to people and comparatively little personal space. This paper examines how a group of pre-service PE teachers in Spain responded to, acted and negotiated touch with primary school students. It draws on data generated from body journals and the concepts of risk society, surveillance and moral panic. The findings indicate that touching school students is still common practice in Spain and was considered something positive. The influence of other individuals and certain spaces was also noted by participants, who felt more surveilled and distressed on particular occasions and some of them strategically introduced touch with students in a progressive manner. The results of the study invite us to reflect on the possibility of doing more harm than good by presenting topics about touch to pre-service teachers and how pre-service teacher educators may need to provide PE students with proper resources and understandings to successfully negotiate touch with school students.
Economic Valuation of Cultural Heritage: Application of Travel Cost Method to the National Museum and Research Center of Altamira
Authors: Torres-Ortega Saúl , Pérez-Álvarez Rubén , Díaz-Simal Pedro , De Luis-Ruiz Julio Manuel , Piña-García Felipe
Published: July 2018

The economic assessment of non-marketed resources (i.e., cultural heritage) can be developed with stated or revealed preference methods. Travel cost method (TCM) is based on the demand theory and assumes that the demand for a recreational site is inversely related to the travel costs that a certain visitor must face to enjoy it. Its application requires data about the tourist’s origin. This work aims to analyze the economic value of the National Museum and Research Center of Altamira, which was created to research, conserve, and broadcast the Cave of Altamira (UNESCO World Heritage Site since 1985). It includes an accurate replica known as the “Neocave”. Two different TCM approaches have been applied to obtain the demand curve of the museum, which is a powerful tool that helps to assess past and future investments. It has also provided the annual economic value estimate of the National Museum and Research Center of Altamira, which varies between 4.75 and 8.00 million € per year.
Assessment of Air Pollution from Household Solid Waste Open Burning in Thailand
Authors: Pansuk Jirataya , Junpen Agapol , Garivait Savitri
Published: July 2018

The purpose of this study was to assess household solid waste management in areas governed by local administrative organizations (LAOs). The obtained results would be used to assess the amount of air pollution emitted from household solid waste open burning. A survey was employed, through the use of questionnaires, to collect data from a random sample of 4300 households residing in areas governed by 96 LAOs. According to the results, it was evident that a total of 26.17 Mt of solid waste were generated per year, of which 6.39 Mt/year was not collected by the LAOs and was eliminated by households. Moreover, the percentage of waste burned on or outside the households’ property was 53.7%, or an equivalent of 3.43 Mt/year of solid waste burned in open areas. In addition, it was found that 0.66 Mt/year of solid waste collected by the LAOs was burned in open areas and was not eliminated properly. Hence, the total amount of solid waste from these two sources was 4.09 Mt/year, which resulted in the emissions of carbon dioxide equivalent, carbon monoxide, sulfur dioxide, nitric oxide, and particulate matter of 1247.3 kt/year, 103.0 kt/year, 1.2 kt/year, 7.4 kt/year, and 19.6 kt/year, respectively.
Behind the Scenarios: World View, Ideologies, Philosophies. An Analysis of Hidden Determinants and Acceptance Obstacles Illustrated by the ALARM Scenarios
Authors: Spangenberg Joachim H.
Published: July 2018

In situations of uncertainty, scenarios serve as input for scientifically informed decision making. However, past experience shows that not all scenarios are treated equally and we hypothesise that only those based on a world view shared by scientists and decision makers are perceived as credible and receive full attention of the respective group of decision makers. While intuitively plausible, this hypothesis has not been analysed by quantitative correlation analyses, so instead of drawing on quantitative data the paper analyses the archetypical scenarios developed in the ALARM project to substantiate the plausibility by a comparative analysis of world views, value systems and policy orientations. Shock scenarios are identified as a means to explore the possibility space of future developments beyond the linear developments models and most scenario storylines suggest. The analysis shows that the typical scenarios are based on mutually exclusive assumptions. In conclusion, a comparison of storylines and empirical data can reveal misperceptions and the need to rethink world views as a necessary step to open up to new challenges. Deeply held beliefs will make this transition unlikely to happen without severe crises, if not dedicated efforts to explicate the role of world views for scenarios and policies are undertaken.
Switchable Interfaces: Redox Monolayers on Si(100) by Electrochemical Trapping of Alcohol Nucleophiles
Authors: Zhang Long , Espíndola Ruth , Noble Benjamin , Gonçales Vinicius , Wallace Gordon , Darwish Nadim , Coote Michelle , Ciampi Simone
Published: July 2018

Organic electrosynthesis is going through its renaissance but its scope in surface science as a tool to introduce specific molecular signatures at an electrode/electrolyte interface is under explored. Here, we have investigated an electrochemical approach to generate in situ surface-tethered and highly-reactive carbocations. We have covalently attached an alkoxyamine derivative on an Si(100) electrode and used an anodic bias stimulus to trigger its fragmentation into a diffusive nitroxide (TEMPO) and a surface-confined carbocation. As a proof-of-principle we have used this reactive intermediate to trap a nucleophile dissolved in the electrolyte. The nucleophile was ferrocenemethanol and its presence and surface concentration after its reaction with the carbocation were assessed by cyclic voltammetry. The work expands the repertoire of available electrosynthetic methods and could in principle lay the foundation for a new form of electrochemical lithography.
Characterisation of the Virome of Tonsils from Conventional Pigs and from Specific Pathogen-Free Pigs
Authors: Blomström Anne-Lie , Ye Xingyu , Fossum Caroline , Wallgren Per , Berg Mikael
Published: July 2018

Porcine respiratory disease is a multifactorial disease that can be influenced by a number of different microorganisms, as well as by non-infectious factors such as the management and environment of the animals. It is generally believed that the interaction between different infectious agents plays an important role in regard to respiratory diseases. Therefore, we used high-throughput sequencing combined with viral metagenomics to characterise the viral community of tonsil samples from pigs coming from a conventional herd with lesions in the respiratory tract at slaughter. In parallel, samples from specific pathogen-free pigs were also analysed. This study showed a variable co-infection rate in the different pigs. The differences were not seen at the group level but in individual pigs. Some viruses such as adenoviruses and certain picornaviruses could be found in most pigs, while others such as different parvoviruses and anelloviruses were only identified in a few pigs. In addition, the complete coding region of porcine parvovirus 7 was obtained, as were the complete genomes of two teschoviruses. The results from this study will aid in elucidating which viruses are circulating in both healthy pigs and in pigs associated with respiratory illness. This knowledge is needed for future investigations into the role of viral-viral interactions in relation to disease development.
There Is Always Another Way! Cytomegalovirus’ Multifaceted Dissemination Schemes
Authors: Jackson Joseph W. , Sparer Tim
Published: July 2018

Human cytomegalovirus (HCMV) is a β-herpes virus that is a significant pathogen within immune compromised populations. HCMV morbidity is induced through viral dissemination and inflammation. Typically, viral dissemination is thought to follow Fenner’s hypothesis where virus replicates at the site of infection, followed by replication in the draining lymph nodes, and eventually replicating within blood filtering organs. Although CMVs somewhat follow Fenner’s hypothesis, they deviate from it by spreading primarily through innate immune cells as opposed to cell-free virus. Also, in vivo CMVs infect new cells via cell-to-cell spread and disseminate directly to secondary organs through novel mechanisms. We review the historic and recent literature pointing to CMV’s direct dissemination to secondary organs and the genes that it has evolved for increasing its ability to disseminate. We also highlight aspects of CMV infection for studying viral dissemination when using in vivo animal models.
Comparison of Different In Situ Hybridization Techniques for the Detection of Various RNA and DNA Viruses
Authors: Pfankuche Vanessa M. , Hahn Kerstin , Bodewes Rogier , Hansmann Florian , Habierski André , Haverkamp Ann-Kathrin , Pfaender Stephanie , Walter Stephanie , Baechlein Christine , Postel Alexander , Steinmann Eike , Becher Paul , Osterhaus Albert , Baumgärtner Wolfgang , Puff Christina
Published: July 2018

In situ hybridization (ISH) is a technique to determine potential correlations between viruses and lesions. The aim of the study was to compare ISH techniques for the detection of various viruses in different tissues. Tested RNA viruses include atypical porcine pestivirus (APPV) in the cerebellum of pigs, equine and bovine hepacivirus (EqHV, BovHepV) in the liver of horses and cattle, respectively, and Schmallenberg virus (SBV) in the cerebrum of goats. Examined DNA viruses comprise canine bocavirus 2 (CBoV-2) in the intestine of dogs, porcine bocavirus (PBoV) in the spinal cord of pigs and porcine circovirus 2 (PCV-2) in cerebrum, lymph node, and lung of pigs. ISH with self-designed digoxigenin-labelled RNA probes revealed a positive signal for SBV, CBoV-2, and PCV-2, whereas it was lacking for APPV, BovHepV, EqHV, and PBoV. Commercially produced digoxigenin-labelled DNA probes detected CBoV-2 and PCV-2, but failed to detect PBoV. ISH with a commercially available fluorescent ISH (FISH)-RNA probe mix identified nucleic acids of all tested viruses. The detection rate and the cell-associated positive area using the FISH-RNA probe mix was highest compared to the results using other probes and protocols, representing a major benefit of this method. Nevertheless, there are differences in costs and procedure time.
Assessing the Hydrodynamic Response of the Mar Menor Lagoon to Dredging Inlets Interventions through Numerical Modelling
Authors: García-Oliva Miriam , Pérez-Ruzafa Ángel , Umgiesser Georg , McKiver William , Ghezzo Michol , De Pascalis Francesca , Marcos Concepción
Published: July 2018

The Mar Menor lagoon has been subjected to high anthropogenic pressures. Among them, in the early 1970s, dredging and enlargement of one of the inlets to make a navigable channel has had strong consequences on the hydrology, ecology, and fisheries of the lagoon. In recent years, changes in agricultural practices have induced an eutrophication process, leading to loss of water quality. As a solution, some management proposals have included dredging of the inlets in order to increase the water renewal. However, these proposals did not take into account the negative effects of previous experiences nor the consequences on environmental conditions of the lagoon and therefore on biological processes. The purpose of this work is to assess the effect that proposed mitigation measures, could have on the hydrodynamic conditions and discuss its possible ecological consequences. A three-dimensional (3D) numerical model has been used to simulate the lagoon under different dredging scenarios, covering different dredging depths and extensions. The simulated current fields and fluxes through the inlets, as well as water renewal times have been compared for the different scenarios. It is found that some of the considered scenarios take the system beyond the threshold of sustainability, where the modified current dynamics could affect sediment transport, beach dynamics and fishing capacities in a significant way. Water exchange with the Mediterranean is also strongly affected, with consequences for species connectivity, and a homogenization of the water renewal times that could lead to loss of ecosystem heterogeneity and structural complexity. The study demonstrates the utility of numerical models as effective tools for the management of coastal areas.
Effect of Green Roof Configuration and Hydrological Variables on Runoff Water Quantity and Quality
Authors: Ferrans Pascual , Rey Carlos Vicente , Pérez Gabriel , Rodríguez Juan Pablo , Díaz-Granados Mario
Published: July 2018

Green roofs (GRs) are a feasible solution for mitigating increased runoff volumes in urban areas. Though many studies have focused their analysis on the quantity and quality of GR runoff, with respect to the relevance of specific site conditions in GR performance, the information gathered for the tropical Andes is not sufficient. This study assessed the hydrological performance and runoff water quality of 12 green roof modular systems located at the Universidad de los Andes campus (Bogotá, Colombia). Based on 223 rainfall events spanning a 3-year period, average rainfall retention was 85% (coefficient of variation = 29%). t-tests, the Welch Test, multiple linear regressions, and correlation analysis were performed in order to assess the potential effect of air temperature, substrate type, vegetation cover, relative humidity, antecedent dry weather period (ADWP), rainfall duration, and rainfall maximum intensity. In some cases, GR design variables (i.e., substrate type and vegetation cover) were found to be significant for describing rainfall retention efficiencies and, depending on the GR type, some hydrological variables were also correlated with rainfall retention. Rainfall and GR runoff from 12 rainfall events were also monitored for total Kjeldahl nitrogen (TKN), nitrates, nitrites, ammonia, total phosphorus (TP), phosphates, pH, total dissolved solids (TDS), total suspended solids (TSS), color, turbidity, biological oxygen demand (BOD), chemical oxygen demand (COD), total coliforms, metals (i.e., zinc, copper, nickel, lead, selenium, aluminum, barium, boron, calcium, strontium, iron, lithium, magnesium, manganese, potassium, sodium), and polyaromatic hydrocarbons (PAHs). The results obtained confirmed that GR systems have the ability to neutralize pH, but are a source of the rest of the aforementioned parameters, excluding PAHs (with concentrations below detection limits), ammonia, TSS, selenium and lithium, where differences with control cases (rainfall and plastic panel runoff) were not statistically significant. Substrate type, event size, and rainfall regime are relevant variables for explaining runoff water quality.
Avec ou sans les proches : la IIe légion Parthique et l’entourage des soldats durant les expéditions de la première moitié du IIIe siècle
Authors: Faure Patrice
Published: July 2018

Of the epitaphs of Legio II Parthica, a hundred or so give us a unique occasion to identify the soldiers’ close relations and social connections in the ordinary camp of Albano, Italy, and the winter quarters of Apamea, Syria. Taking the sources’ limits and distortions in consideration, the study shows that families and civilians were far more present in Albano than in Apamea, although not completely absent from the last one. Different reasons can explain the choices of legionaries to move with or without their families and servants. Also, a specific expeditionary context explains the necessity to adapt social and cultural behaviours and that closer relationships grew between soldiers.
A pyridinium/anilinium [2]catenane that operates as an acid–base driven optical switch
Authors: Vella Sarah J , Loeb Stephen J
Published: July 2018

A two-station [2]catenane containing a large macrocycle with two different recognition sites, one bis(pyridinium)ethane and one benzylanilinium, as well as a smaller DB24C8 ring was synthesized and characterized. 1H NMR spectroscopy showed that the DB24C8 ring can shuttle between the two recognition sites depending on the protonation state of the larger macrocycle. When the aniline group is neutral, the DB24C8 ring resides solely at the bis(pyridinium)ethane site, while addition of acid forms a charged benzylanilinium site. The DB24C8 then shuttles between the two charged recognition sites with occupancy favoring the bis(pyridinium)ethane site by a ratio of 4:1. The unprotonated [2]catenane has a deep yellow/orange color when the DB24C8 ring resides solely at the bis(pyridinium)ethane site and changes to colorless when the crown ether is shuttling (i.e., circumrotating) back and forth between the two recognition sites thus optically signalling the onset of the shuttling dynamics.