bluuebunny/crossref_metadata_2025 huggingface dataset:
AVALIAÇÃO DE UM INSTRUMENTO DE CONTROLE QUANTITATIVO DA PARTICIPAÇÃO DISCENTE NA PRÁXIS PEDAGÓGICA EM EDUCAÇÃO FÍSICA: UM RELATO DE EXPERIÊNCIA
Authors: DE LUCENA ADRIANO ROBSON NOGUEIRA
Published: January 2024

Introdução: As peculiaridades de se avaliar a participação dos alunos nas aulas de Educação Física tem se mostrado um desafio constante. Registrar e controlar as variáveis de participação nas aulas práticas se torna burocrático e cansativo considerando que avaliar individualmente 40 a 50 alunos de forma precisa e objetiva é tarefa árdua. Objetivo: O presente estudo objetivou avaliar um instrumento digital criado para fazer a gestão e avaliação da participação do estudante nas aulas práticas. Métodos: O estudo se caracteriza como relato de experiência de campo documental, sendo os dados de frequência às aulas coletados e registradas de forma agregada em duas turmas de 2º ano do ensino médio integrado em uma escola da rede federal de ensino, sem ocorrer a identificação de nenhum participante, contendo um total amostral de 75 alunos, sendo 37 do sexo masculino e 38 do sexo feminino, em aulas práticas da disciplina. Foi utilizada uma planilha desenvolvida no software “Excel” para os registros das variáveis de participação. Utilizou-se para análise estatística descritiva comparativa o teste “t” de Student para amostras independentes. Resultados: Quando comparadas as amostras, ocorreram diferenças significativas entre os bimestres (p<0,05), porém não houve diferenças significativas entre as turmas, evidenciando um aumento na participação dos alunos entre os bimestres. Conclusão: o instrumento se mostrou eficaz em registrar e avaliar quantitativamente turmas e variáveis diferentes, podendo ser aplicado como forma de gerir a participação dos alunos nas aulas práticas.
NOS BASTIDORES DA BOLA: DISCUSSÕES SOBRE GÊNERO E REPRESENTATIVIDADE DA MULHER NO FUTSAL
Authors: DOS SANTOS GREZIENE , SOUZA DE PAULA KAREN , UCHOA ISABEL
Published: January 2024

Introdução: A Educação Física e o esporte, hoje, são campos férteis para discussões de gênero, porém, os mesmos carecem de estudos que abordem especificamente as relações de preconceitos que ainda são recorrentes nos esportes. Situações de preconceito ou discriminação são evidentes na prática do futsal, por exemplo - levando assim ao estudo acerca da abordagem entre as relações de gênero no futsal. Objetivo: o objetivo do presente artigo é analisar as relações de gênero presentes na trajetória de mulheres treinadoras de futsal feminino, buscando compreender quais discursos de interdição as rodeiam. Métodos: Optou-se, como método de pesquisa - pela entrevista do tipo semientruturada que combina questões fechadas e com questões abertas, dando a oportunidade à participação mais ampla das entrevistadas. Resultados: Dentre a população de mulheres ouvidas, cerca de 74% alegam que já foram vítimas de discursos misóginos ou machistas no trabalho, e quando perguntadas se elas se sentem amparadas ou protegidas pela instituição pelo qual prestam seu trabalho como treinadoras, a maior parcela (78%) afirmam que não. Conclusão: A baixa representatividade das mulheres em cargos de gerência no esporte é consideravelmente analisada, hoje – devido à predominância dos homens ocupando funções de treinadores, ratificando a característica generificada do esporte e sua reprodução de estereótipos sociais sobre os lugares ocupados por homens e mulheres.
A QUALIDADE DE VIDA ASSEGURADA PELA EDUCAÇÃO FÍSICA E PELO EXERCÍCIO FÍSICO
Authors: BEZERRA ALANA SIMÕES , SANTOS VICTOR JAY TAVARES DOS , NASCIMENTO MARCOS ANTONIO MEDEIRO DO
Published: January 2024

Introdução: Está prevista na Constituição da República Federativa do Brasil, na Declaração Universal dos Direitos do Homem, que é dever do estado promover as condições para que a população tenha acesso à saúde e à qualidade de vida. Objetivo: Analisar como os efeitos da educação física e do exercício físico corroboram para assegurar a qualidade de vida dos praticantes do exercício físico. Métodos: Trata-se de uma pesquisa de campo, com abordagem quantitativa, a qual está relacionada em um primeiro momento, à análise das leis e das normas que regulam a educação física no Brasil, na busca de compreender a forma como o exercício físico promove a qualidade de vida dos praticantes de musculação e como ela está prevista na legislação brasileira. Para avaliação da qualidade de vida foi utilizado o questionário SF-6D. participaram 30 praticantes do exercício físico. Resultados: A qualidade de vida dos 30 (trinta) participantes distribuíram-se na forma que segue: 03 (três) indivíduos inseridos na casa 0,85 a 0,86; 17 (dezessete) indivíduos representados na faixa de 0,9 a 0,95; 10 (dez) indivíduos incluídos na faixa de 0,95 a 1 na escala standart gamble. Verifica-se que quanto mais o resultado se aproxima de 1 melhor será a qualidade de vida do avaliado. Conclusão: comprovou-se que os praticantes do exercício físico atingiram um indicativo de qualidade de vida muito próxima do nível máximo da escala utilizada pelo questionário SF-6D, fato que corrobora com a assertiva de que o exercício físico promove uma melhora na qualidade de vida.
NEUROCIÊNCIA NA EDUCAÇÃO FÍSICA: ATIVIDADE CEREBRAL DE ESCOLARES DE RONDÔNIA
Authors: Biet de Sousa Geovane , Da Silva Giovanna Eduarda , Araújo Justiniano Arthur Franclin , Prado Ferreira Imanuel , De Oliveira Neto João Bernardino , Teixeira de Pinho Silvia , Rocha Calomeni Maurício
Published: January 2024

Introdução: é um consenso que os exercícios físicos induzem mudanças neuroplásticas que estão associadas a melhorias de funções cognitivas. Objetivo: o presente estudo objetivou traçar um perfil da atividade cerebral de escolares por meio dos registros de eletroencefalografia (EEG) dos traçados das ondas cerebrais e relacionar às variáveis executoras: memória de trabalho, atenção concentrada e velocidade de processamento mental. Métodos: a amostra foi composta por 23 escolares de 10 a 12 anos de idade pertencentes a uma escola pública da cidade de Porto Velho - Rondônia. Utilizou-se a EEG para revelar mudanças no estado cerebral. Para o teste de atenção concentrada foi utilizado o teste de grade, para o teste de memória foi utilizado o DigitSpan e para analisar a velocidade de processamento mental foi utilizado o teste de tempo de reação de dupla escolha. Resultados: os resultados mostraram que nas faixas de frequência Delta e Theta foram registradas as maiores atividades em milivolts durante o repouso. Os testes de memória de trabalho tiveram a média de 4 números na ordem correta. Referente ao teste de atenção concentrada a média foi 9 pontos. Por fim, o tempo médio que os alunos reagiram ao estímulo foi de 384 milissegundos. Conclusão: a correlação positiva indica que provavelmente ocorreu um aumento da atividade Alfa, produzindo um aumento nos escores do teste de atenção concentrada. A correlação negativa indica que um aumento na atividade Beta 1 na área F7 provavelmente promoveu uma diminuição do tempo de reação motora, o que significa um aumento na velocidade de processamento mental.
EFEITO PÓS-EXERCÍCIO RESISTIDO SOBRE A PRESSÃO ARTERIAL DE MULHERES ADULTAS HIPERTENSAS
Authors: Maia Divanalmi Ferreira , Luis Pessoa de Farias Álvaro , Antônio Medeiros do Nascimento Marcos , Souto Filho José Morais , Alves da Costa Rosa Maria , Nonato de Lima Daiane
Published: January 2024

RESUMO

 

O estudo objetivou verificar o efeito agudo do exercício resistido sobre a pressão arterial (PA) de mulheres adultas hipertensas. Método: Cinco mulheres com idade entre 40 e 50 anos, experientes em treinamento resistido (TR), foram submetidas ao teste de 1 repetição máxima (1RM) em quatro exercícios. Após 48 horas da realização dos testes de 1RM, foram realizadas as sessões de TR em dois dias não consecutivos: 1° dia as duas mulheres e no 2º dia as três mulheres realizaram os quatro exercícios propostos em três séries de 20 repetições com carga entre 40 e 60% para 1RM, 40 segundos de intervalo entre as séries e 1min entre os exercícios. A PA foi aferida pelo pesquisador após 5 minutos de repouso pré - TR e 20 min pós – TR. Resultados: Foi encontrada alteração significativa na PA após utilização do protocolo. Ocorrendo assim uma diminuição significativa tanto na PA sistólica quanto na PA diastólica pós 20 minutos da realização do TR. Conclusão: O presente estudo demonstrou que o TR com carga entre 40 e 60% da máxima provoca queda significativa tanto PA sistólica quanto na PA diastólica quando aferidas 20 minutos após o término da sessão de exercícios. A pesquisa será de importante contribuição, pois ainda existem poucos estudos científicos que relacionam os reais benefícios do exercício resistido sobre a PA de adultos hipertensos.

Palavras-chave: Treinamento resistido. Pressão arterial. Efeito agudo.
TREINAMENTO DE FORÇA PARA IDOSOS NO TRATAMENTO A SARCOPENIA
Authors: FARIAS ÁLVARO LUIS PESSOA DE , Nascimento Marcos Antônio Medeiros do , Souto Filho José Morais , Alves da Costa Rosa Maria , Nonato de Lima Daiane , Ferreira Maia Divanalmi
Published: January 2024

Através do desenvolvimento natural do corpo, o processo de envelhecimento chega à todos os indivíduos, sejam estes praticantes ou não de atividade física e o processo sarcopênico vem junto, de forma inerente ao envelhecimento. Visando compreender e fomentar o debate acerca do impacto da atividade física, mais precisamente do treinamento de força, na contenção dos avanços da sarcopenia para idosos, é que se deu esta pesquisa. Dito isto, o estudo se concentrou na análise literária e comparativa entre artigos selecionados que contemplassem descritores relacionados ao envelhecimento, sarcopenia e treinamento de força e que considerasse exclusivamente esta prática física na análise responsiva de idosos contra o avanço sarcopênico. Através do comparativo entre artigos e das análises feitas, tornou-se possível afirmar que a prática do treinamento de força para idosos tem inúmeros benefícios, dentre eles, a melhora na musculatura, na densidade óssea, na coordenação motora, assim como qualidade de vida. Entretanto, vale reiterar que, para que se torne possível a implementação desta prática para a população idosa faz-se necessário um conhecimento específico que os profissionais de educação física dispõem.

Palavras-chave: Envelhecimento. Treinamento de foça. Sarcopenia. Profissional da Educação Física.
O USO DA FONOFORESE EM DOENÇAS DO SISTEMA MUSCULOSQUELÉTICO
Authors: Cunha Hortêncio Marco Antônio
Published: January 2024

Introdução:  O uso  do ultrassom (US) em diferentes aplicações na área da saúde  tem ganhado destaque, devido ao fato do US poder ser usado como fonte de energia para a ocorrência de reações químicas. O US apresenta diferentes formas de uso, nas mais variadas frequências, sendo que na área da fisioterapia seu uso ocorre nas frequências de 1 e 3 MHz. Na fisioterapia, o ultrassom terapêutico consiste na utilização do aparelho para efeitos térmicos na região que necessita de tratamento: redução da dor, redução de espasmos musculares, aumento da extensibilidade tecidual e melhora do fluxo sanguíneo local.    A fonoforese é uma técnica que facilita a penetração cutânea através da energia ultrassônica na desorganização da estrutura lipídica da epiderme, utilizando como meio de contato entre o cabeçote do aparelho e a pele com medicamento.  O objetivo do presente estudo é investigar e  evidenciar o efeito da utilização da fonoforese em alterações musculoesqueléticas.   Métodos: Resultados:dos resultados e desfechos dos estudos escolhidos, observou-se que a maioria desses estudos utiliza desfechos semelhantes. Como resultado, em síntese, a maioria dos estudos concluiu que o uso da fonoforese foi eficaz para os desfechos avaliados, em curto prazo, e principalmente que esse tratamento foi eficaz, facilitando a redução da inflamação e da dor e das alterações musculoesqueléticas. Conclusão: Todos os estudos demonstraram efeito positivo da fonoforese no alívio da dor, redução da rigidez articular, melhora da capacidade funcional e função física nos distúrbios musculoesqueléticos.

Palavras-chave: Ultrassom terapêutico, fisioterapia, fonoforese,sistema musculoesquelético.
"CIVIL IDENTITY" OF YOUTH IN THE CONDITIONS OF INDEPENDENT KYRGYZSTAN
Authors:   Kyrgyz State University named after I.Arabaev, Nusubalieva Eliza
Published: January 2024

This article reveals issues related to civic identity. In a social context, the civic identity of young people is an important factor for social development. The quality of civic identity affects the quality of social practices and social development. In conditions of social change, civic identity can take on various forms, which can affect the socialization of young people and, accordingly, their ability to accept the values of this society. In a stable society, issues of civic identity are not as acute as in Kyrgyzstan, which is characterized by high mobility, instability and variability of social reality. Kyrgyzstan is facing the problem of preserving its identity as a system that is reproduced and oriented both towards integration into the world community and the preservation of its unique values and goals. Social development is based on certain patterns that serve as the basis for identifying new generations with society in its main sociocultural dimensions.
Challenging issues of implementing enhanced recovery after surgery programs in South Korea
Authors: Yoon Soo-Hyuk , Lee Ho-Jin
Published: January 2024

This review discusses the challenges of implementing enhanced recovery after surgery (ERAS) programs in South Korea. ERAS is a patient-centered perioperative care approach that aims to improve postoperative recovery by minimizing surgical stress and complications. While ERAS has demonstrated significant benefits, its successful implementation faces various barriers such as a lack of manpower and policy support, poor communication and collaboration among perioperative members, resistance to shifting away from outdated practices, and patient-specific risk factors. This review emphasizes the importance of understanding these factors to tailor effective strategies for successful ERAS implementation in South Korea’s unique healthcare setting. In this review, we aim to shed light on the current status of ERAS in South Korea and identify key barriers. We hope to encourage Korean anesthesiologists to take a leading role in adopting the ERAS program as the standard for perioperative care. Ultimately, our goal is to improve the surgical outcomes of patients using this proactive approach.
Territorialización, territorialidades y geografías del extractivismo ilícito en la región de Ucayali en Perú
Authors: Soberón-Garrido Ricardo
Published: January 2024

El objetivo del presente artículo es doble. Por un lado, mostrar los impactos de la presencia del narcotráfico en la región de Ucayali, para revelar una situación que, salvo ocasiones muy raras, no está actualmente en las agendas públicas, entre las prioridades políticas y económicas, en los debates parlamentarios y en las decisiones jurisdiccionales. Por otro lado, hacer una propuesta directa y efectiva para resolver los viejos y los más recientes dilemas que representa el narcotráfico de cocaína y sus derivados, sus causas y consecuencias para los pueblos indígenas que habitan la Amazonía peruana. Se toma el caso de Ucayali, una región estratégica ubicada en la Amazonía central peruana. La investigación se nutre del análisis y el contraste entre la información oficial del Estado peruano, aquella que proviene de organismos internacionales, así como de las propias organizaciones indígenas y de entidades privadas que trabajan en dicha región. Como conclusión, se identifica un orden de acciones que el Estado peruano debe ejecutar en la región de Ucayali para cerrar las brechas sociales históricas que se encuentran en la base del territorio donde se ha asentado el narcotráfico.
COTTIDAE FISH OF WESTERN KAMCHATKA SHELF, THE CURRENT STATE OF THEIR FISHING AND PROCESSING
Authors:   Kamchatka Branch of the Russian Federal Research Institute of Fisheries and Oceanography (KamchatNIRO), Matveev A.A , Terentiev D.A. ,   Kamchatka Branch of the Russian Federal Research Institute of Fisheries and Oceanography (KamchatNIRO)
Published: January 2024

The work is devoted to the long-term monitoring of Cottidae fishing which inhabit the shelf off the western coast of Kamchatka (Sea of Okhotsk). According to the results of marine scientific expeditions carried out in different seasons of the year the estimates of the catch (by-catch) of gobies by fishing gear are given. The proportion of fish that is not taken into account in official statistics in bottom longline fishing is estimated. Possible prospects and directions of use of the studied objects of fishing are shown.
Translingual practice in remote EFL tertiary education: How multilingual speakers create translanguaging spaces
Authors: Umam Akhmad Hairul , Sugiharto Setiono , Manara Christine
Published: January 2024

Published studies on translingual practice in the pedagogical realms have burgeoned in the current literature, generating important insights into how communication has become dynamic and fluid. However, these studies have focused almost exclusively on face-to-face, in-person interactions. As COVID-19, which hit all domains of life (including education) worldwide, has compelled schools to conduct remote learning interaction, it will be more revealing to pursue further how translingual practice is enacted in a virtual classroom. Drawing on the notion of translingual perspective (Canagarajah, 2013), this study investigated how English as a Foreign Language (EFL) teachers and learners at tertiary education created a translingual space in their interactions by deploying specific negotiation strategies and various multimodal resources in a digital learning platform. Employing a netnography method and interactive model (Miles Huberman, 1994), this study employed virtual observation, surveys, and interviews as the sources of data. The study has revealed the complexity of translingual practices in EFL remote learning interactions that occurred naturally in different parts of teaching-learning activities. The use of verbal, semiotic, and multimodality resources as negotiation strategies for meaning-making plays essential roles in facilitating fluid and dynamic interactions. Pedagogically, the interaction in EFL remote learning has been found to be more multilaterally engaging.
MOOC as a technology-focused TPD for EFL teachers in Indonesia
Authors: Jati Anuncius Gumawang
Published: January 2024

This study examines participants’ expectations, perception of the learning experience, and factors contributing to satisfaction with the MOOC of a technology-focused TPD program, a professional development initiative focused on enhancing English teachers’ technology integration skills. It was participated by 200 EFL teachers in Indonesia. They were engaged in the program components such as MOOC modules, Classroom Ideas, and Community of Practice (CoP). A mixed-methods approach combined pre- and post-MOOC surveys for quantitative data collection and thematic analysis of interview data to gain deeper insights into participants’ responses. The findings indicated high participant expectations, reflecting initial interest and commitment to the program. The participants demonstrated dedication to learning and acquiring new knowledge and skills, highlighting the potential impact on learning outcomes. However, time management and internet connectivity challebges posed barriers to translating learning into practice. The CoP component was also highlighted for improvement to support the learning process better. These findings contributed to teacher professional development by offering insights for program designers and policymakers. Aligning the program with participants’ needs, providing ongoing support, and fostering collaboration could enhance the effectiveness of the MOOC of technology-focused program and promote the professional growth of English language teachers in Indonesia.
Gene Expression, Growth Performance and Body Composition of Labeo rohita Fingerlings Fed on Polyphenols Supplement
Authors: Hussain Syed Makhdoom , Jamil Muniba , Ali Shafaqat , Shahzad Muhammad Mudassar , Hussain Majid , Ahmad Nisar , Riaz Danish
Published: January 2024

The aim of this research was to investigate the impacts of polyphenols-supplemented diet on growth, body composition and gene expressions of insulin-like growth factor (IGF) and growth hormone (GH) in Labeo rohita fingerlings fed canola meal-based diets. Two plant extracts; Salvadora persica and Salvadora oleoides were used to assess the efficacy of L. rohita. Twelve test diets, including control (no supplementation) and supplemented with S. persica, S. oleoidesand their mixture at the levels of 200, 400 and 800 mg/kg, were formulated. The gene expression of IGFs and GH was observed to be regulated significantly (p< 0.05) in the liver tissue of fingerlings when fed with supplemented diet. The highest expression of GH was observed at 200 mg/kg mixture diet. The results of growth performance showed that maximum weight gain% (215%) and SGR (1.63) was recorded at 200 mg/kg mixture diet. The results of carcass analysis showed that they were significantly (p< 0.05) influenced by supplemented diet when compared with control diet. As growth performance is under genetic control, the synthesis and release of IGF are stimulated by binding of GH to receptors present in the liver. Conclusively, the results showed that rohu fingerlings shown the best results of growth performance, body composition and gene expression of IGF and GH, when fed on mixture of S. persica and S. oleoides at 200 mg/kg.
Sedimentological Analysis of Thin-Bedded Sequence of Eastern Part of West Crocker Formation, Northwest Sabah, Malaysia
Authors: Mohd Radzir Nurul Afifah , Arshad Athifah , Ali Che Aziz , Mohamed Kamal Roslan
Published: January 2024

It has been suggested that the eastern part of the West Crocker Formation is the slope to the inner fan of a deep-water system. Detailed sedimentological examination of eight outcrops of this formation in this study identified four types of facies: interbedded sandstone and mudstone facies (F1), chaotic facies (F2), and mudstone facies (F3). The immature textures and deformations with rolled-over sandstone block deposits occur as infers due to the presence of an angle of loose sediments, while the repeated thinly bedded sandstones and mudstones were recognized as levee-channel complexes. The overbank was identified as thick mudstone deposits. The sandstone deposits are synonymous with strong energy carried by the head of the turbidity current, while the fine to very fine sediment grains are typical of sediments that are carried by the body and tail of turbidity current and may deposited far away from the first deposition of sand. All the characteristics presence in the environment of slope are to the inner fan of a deep-water system with deformed structures. This deformed slope is believed to be part of a late Eocene accretionary complex formed during the Sabah orogeny.
Production of Gamma Aminobutyric Acid (GABA)- MISO Using Candida parapsilosis Isolated from a Commercial Soy Sauce MOROMI
Authors: Chong Shin Yee , Ilham Zul , Mohd Zaini Nurul Aqilah , Abd Rahim Muhamad Hafiz , Siva Raseetha , Raposo António , Alarifi Sehad N , Lani Mohd Nizam , Wan-Mohtar Wan Abd Al Qadr Imad
Published: January 2024

A newly identified yeast, Candida parapsilosisstrain KBC (CPSKBC) was tested for its GABA-producing potential in miso fermentation and consumer acceptability towards the GABA-miso was evaluated through sensory analysis. Three different formulations were used over one month to make the GABA-miso: formulation 1 (F1) used soybeans, rice koji, and miso starter; formulation 2 (F2) used soybeans, rice koji, and CPSKBC suspension; and formula 3 (F3) used soybeans, rice koji, miso starter, and CPSKBC suspension. High Performance Liquid Chromatography (HPLC) was used to measure the gamma-aminobutyric acid (GABA) concentration of the miso produced. F3 produced the highest GABA (36.73 mg/L), followed by F2 (34.54 mg/L) and F1 (28.42 mg/L). Sensory evaluation was conducted with 60 panelists using a 9-point hedonic scale. For all the sensory attributes evaluated (appearance, color, odor, taste and overall acceptability), the results showed no significant differences (p >0.05) between groups of miso (F1, F2, and F3) and commercial miso (C1). We can conclude that our products (F1, F2, and F3) matched with commercially produced miso in the market. This study demonstrated that CPSKBC was able to produce GABA-miso (F2 and F3) which is acceptable to the consumer.
Synthesis, Antimalarial Activities of Secondary Amine-Substituted Eugenol Compounds Against Plasmodium falciparum and in silico Molecular Docking Analysis
Authors: Syahri Jufrizal , Hilma Rahmiwati , Nurlaili Nurlaili , Sari Meidita Kemala , Frimayanti Neni , Ali Amatul Hamizah , Latip Jalifah
Published: January 2024

Multi-resistance cases with antimalarial drugs had been developed in over the years. One of the ways of developing antimalarial drugs is to focus on searching for the potential antifolate inhibitors against Plasmodium sp. from synthetic or natural products. The aims of this research was to synthesis secondary amine-substituted eugenol compounds through the Mannich reaction for antimalarial evaluation using Plasmodium falciparum 3D7. The compounds were also evaluated on Plasmodium falciparum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) as a protein target and the compounds’ drug-likeness properties were determined. Five secondary amine-substituted eugenol compounds (1a-e) were synthesized via substitution of the secondary amine i.e., pyrrolidine, piperidine, methyl piperidine, and morpholine in the eugenol structures. The plasmodium lactate dehydrogenase assay (pLDH) showed that 1a and 1c had good antimalarial effects against P. falciparum 3D7 with the IC50s values of 0.89 mM and 0.62 mM, respectively. The molecular docking analysis showed that 1a and 1c had perfect interaction with PfDHFR-TS (PDB ID: 1J3I) with strong hydrogen bond interactions occurring with PfDHFR-TS protein. The eugenol derivatives 1a and 1c exerted CDOCKER binding energies of -6.1407 and -6.6536 kcal/mol, respectively. Based on this research, it was found that PfDHFR-TS is a plausible protein target for the synthesized secondary amine-substituted eugenol in P. falciparum infection. The substitution of a secondary amine group for eugenol significantly enhanced the antimalarial properties of the compounds. Thus, eugenol derivatives are potential compounds to be pursued to combat folate resistance in malarial infection.
Relationship Between Obesity and Infertility among Women with Polycystic Ovarian Syndrome Treated at The National Population and Family Development Board (NPFDB) Malaysia
Authors: Husin Hasnoorina , Mohd Yussof Mohd Azizuddin , Hamid Asmah , Ishak Ismarulyusda , Budin Siti Balkis
Published: January 2024

Polycystic ovarian syndrome (PCOS) is a metabolic dysfunction and is closely related to infertility in women. Obesity has an impact on the clinical manifestations of PCOS. This study was designed to determine the relationship between obesity and infertility among women with PCOS treated at the National Population and Family Development Board (NPFDB) Malaysia. This is a cross-sectional study with a simple random sampling technique involving infertile women attending NPFDB Subfertility Clinic, Kuala Lumpur, Malaysia, from January 2018 to December 2019. Clinical and menstrual history were recorded, and subjects underwent physical examination by a medical doctor. Subjects were diagnosed with PCOS based on Rotterdam criteria, and blood was taken for reproductive hormone, blood glucose, cholesterol, and triglyceride determination. A total of 179 infertile women completed the study, and 84 (47%) were diagnosed with PCOS. Results showed a significant increase in follicle-stimulating hormone (FSH) levels along with a significant reduction in progesterone level (p<0.05) in PCOS women compared to non-PCOS women. A total of 44% of PCOS women were found to be obese, and they exhibited significantly higher blood pressure and triglyceride level but lower high-density lipoprotein (HDL) level (p<0.05). Chi-square (χ2) showed PCOS women who are obese are more likely to experience ovulatory dysfunction, as evidenced by oligo- and amenorrhea, compared to non-obese women with PCOS. In addition, they were also presented with significantly higher testosterone levels (p<0.05) and reduced progesterone levels compared to non-obese PCOS women. This study showed that PCOS women with obesity had more prominent ovulatory dysfunction and reproductive hormonal imbalance than non-obese PCOS women. These findings suggest that PCOS women with obesity are more prone to develop infertility.
Zerumbone: A Potent Emerging Phytochemical with Anticancer Therapeutic Potential
Authors: Ahmad Jamil Nur Aqilah Huda , Hoongli Sylvia Chong , Abdullah Nurul Akmaryanti , Mohamad Zakuan Noraina , Abdul Hamid Hafizah , Mehat Muhammad Zulfadli , Cheema Manraj Singh , Md Hashim Nur Fariesha
Published: January 2024

Breast cancer is a prevalent cause of global mortality, characterised by abnormal cell growth within the breast. These cells can spread to distant sites in the body through metastasis and one of the mechanisms that breast cancer cells use to metastasise is via invadopodia formation. Accumulated evidence has explained pathways that may contribute to the breast cancer cells metastasis including the ERK, SMAD-3, STAT3 and NF-κB pathways. The hypoxic conditions within tumours enhance their metastatic ability through HIF-1α upregulation. Despite advanced treatments including chemotherapy and radiotherapy, these approaches are expensive and sometimes lack efficacy. Zerumbone, a compound extracted from Zingiber zerumbet, is known for its anti-cancer properties. It counteracts cancer cell metastasis by reducing cell migration, invasion, and proliferation by acting upon multiple signalling pathways. This review recapitulates the metastasis of breast cancer and its biomarkers. In addition, our review will also explore the impact of zerumbone, therapeutic roles and its mechanism of action in reducing breast cancer metastasis.
The Potential Place of Tabii in Global Competition: What Do Story Structures Tell Us?
Authors: ÇELİK Kemal
Published: January 2024

This article focuses on TRT's (Turkish Radio and Television Corporation) digital platform called "Tabii," which was launched in 2023. Tabii is a platform constructed with state support during a time when it is becoming progressively challenging to individually counter global content monopolies such as Netflix and Disney. Tabii embraces a kind of eastern tradition and internalizes the values of Turkish Islamic thought under the slogan of "stories that unite us." With this approach, Tabii seeks to challenge the previously established and dominant digital platforms or create an alternative space. It is evident that such an endeavor is quite challenging.

In this research, focusing on loglines and story structures, the themes and character depth of the series are evaluated. For the purpose of sampling, the 10 most-watched series on the Tabii platform were selected, and their story structures and themes were subjected to structural analysis. In conclusion of this analysis, while Tabii's targeted broadcasting approach and advocated human values are deemed significant, the narrative sentences and story structures employed for their conveyance have been found to be weak. Hence, this article highlights the importance of Tabii platform in the context of communication and content creation in the digital world, emphasizing the potential for conveying their messages more effectively with stronger story structures.
Changing Gatekeepers in the New Media Age: An Analysis of Internet Newspapers and Twitter
Authors: HASANÇEBİ Elif , YILMAZ Adem
Published: January 2024

The study aims to reveal the relationship between the user, who has the role of "secondary gatekeeper" with social media, and online newspapers. Thus, this study provides information about the secondary gatekeeping role by helping us understand the relationship between online newspapers, social media and secondary gatekeepers. Thus, this study helps us to understand the relationship between online newspapers, social media and secondary gatekeepers and provides information about the role of secondary gatekeeping. In the study, the news published by media organizations that carry out journalistic activities on Twitter, a social media platform, and the rate and nature of the interaction given to this news by users were examined using qualitative research methods. Therefore, it includes findings that will help to determine the popularity of the news published by online newspapers on Twitter, the topics to which they direct interest, and what kind of reactions are generated by the users. The sample of the study consists of the news published on Twitter between 5-9 December 2022 by internet newspapers such as Aykırı, Ensonhaber, GZT and Pusholder, which actively publish on Twitter in Turkey. Numerical values related to the research findings are presented in frequency and percentage tables and graphs. According to the research findings, it has been determined that Twitter users influence online newspapers in the news publishing process and thus assume a secondary threshold watchdog role.
CONCEPT “ANTIQUITY” IN THE DRAMATIC WORKS OF LESIA UKRAINKA
Authors:   National Air University, Kyiv, Ukraine, Prysiazhniuk Olga M.
Published: January 2024

The article is devoted to the study of the conceptualization of their own and general nominations with the value of antiquity in Lesia Ukrainka drama “Iphigenium in Tavrid” and “Orgy”. Scientific results complement the linguistic categories of linguosophical categories “Concept”, “Conceptual Picture of the World” and “Language Picture of the World”. The linguistic picture of the world is seen as a formal means of expression of a specific ethnos. The concept is understood as a system of concepts, united by a general integrated seven, which is a complex of semi-seven and books and their relationships. The article is studied by anthroponyms, toponyms, ethnons with antiquity value through the prism of the author’s style of Ukrainian poets Lesia Ukrainka. It has been established that the set of nominations for the designation of antiquity recorded in Lesia Ukrainka’s drama “Iphigenya in Tavriya” and “Orgy”, forms a conceptual system of antiquity, which has a clear paradigmatic structure, namely: 1) Lexical and grammatical discharge → 2) Lexical -mantic group → 3) Lexical-semantic subgroup. The concept of “antiquity” is formed from its own and common nominations. General names presented by ethnons, ons are represented by anthroponyms and toponyms. Receiving inventory allowed to allocate 38 nominations with the integral seven “antique”. The conducted research indicates a significant advantage of ancient Greek nominations over Latin (only 6 nominations of Latin origin and significance – in contrast to 32 Greek nominations). The concept of “antiquity” as a set of nominations with the value of antiquity recorded in Lesia Ukrainka drama “Iphigenium in Tavriya” and “Orgy”, expresses the language picture of Ukrainians leading the motive of Byzantine on the territorial, political and similar “ego”.
Imaging Upper-Mantle Anisotropy with Transdimensional Bayesian Monte Carlo Sampling
Authors: Del Piccolo Gianmarco , VanderBeek Brandon P. , Faccenda Manuele , Morelli Andrea , Byrnes Joseph S.
Published: January 2024

Underdetermination is a condition affecting all problems in seismic imaging. It manifests mainly in the nonuniqueness of the models inferred from the data. This condition is exacerbated if simplifying hypotheses like isotropy are discarded in favor of more realistic anisotropic models that, although supported by seismological evidence, require more free parameters. Investigating the connections between underdetermination and anisotropy requires the implementation of solvers which explore the whole family of possibilities behind nonuniqueness and allow for more informed conclusions about the interpretation of the seismic models. Because these aspects cannot be investigated using traditional iterative linearized inversion schemes with regularization constraints that collapse the infinite possible models into a unique solution, we explore the application of transdimensional Bayesian Monte Carlo sampling to address the consequences of underdetermination in anisotropic seismic imaging. We show how teleseismic waves of P and S phases can constrain upper-mantle anisotropy and the amount of additional information these data provide in terms of uncertainty and trade-offs among multiple fields.
Operational Earthquake Forecasting in Japan: A Study of Municipal Government Planning for an Earthquake Advisory or Warning in the Nankai Region
Authors: Goltz James D. , Yamori Katsuya , Nakayachi Kazuya , Shiroshita Hideyuki , Sugiyama Takashi , Matsubara Yu
Published: January 2024

A team of social scientists from the United States and Japan has conducted a study exploring the extent to which municipal governments in Japan have developed plans for response to an operational earthquake forecast from the Japan Meteorological Agency (JMA), indicating that seismic activity in the Nankai trough region has elevated the short-term probability that a major earthquake may occur. Employing both survey research and in-depth interviews, the team explored various aspects of the history and science behind the alerting system, guidance from the national government of Japan, and planning by local jurisdictions for a possible future Nankai trough major earthquake. The survey included questions regarding planning actions included in response plans for receipt of “special earthquake warning information” as well as questions regarding challenges in the planning process, expectations that an earthquake would follow the issuance of an alert, and whether planning would reduce the number of fatalities and injuries. We also conducted in-depth interviews that explored the scientific basis for the alerting system and asked working disaster managers in the Nankai region what they had done to plan and the reasons for not planning if plans had not been developed. We received 469 responses from a total of 736 jurisdictions that comprise the Nankai region—a response rate of 63.7%. We conducted a total of 17 in-depth interviews. In general, we found that a majority of jurisdictions have response plans for receipt of an alert from the JMA; however, the plans lacked a number of planning elements considered important from a disaster management perspective. In addition, many smaller jurisdictions lacked the staffing, resources, and guidance to form comprehensive response plans. Our report identifies both the strengths and weaknesses of existing plans, and outlines a program for improving planning in the region.
Intraoperative maternal complications of the caesarean section: a cross-sectional study at the Provincial general hospital of Kananga in Democratic Republic of Congo
Authors: Kayembe Antoine Tshimbundu , Biakutuele Beya Trésor , Molere Mikando Clovis
Published: January 2024

Background: The maternal complications of caesarean section make it considered a riskier route of delivery than the vaginal route. The caesarean patient in fact combines the risks of giving birth and those of abdominal surgery. The intraoperative complications can compromise the vital prognosis and the obstetrical and functional future of the parturient. The aim of our study was to determine the epidemiological, clinical and therapeutic profile of intraoperative maternal complications of cesarean section at the Provincial General Hospital of Kananga from January 1, 2014 to December 31, 2020.
Methods: This cross-sectional study is performed on a series of cases from the medical files of caesarean patients who suffered from intraoperative complications of caesarean section and based on non-probabilistic sampling of suitability for case selection. Our sample is constituted of 361 cases of intraoperative complications of caesarean section.
Results: The frequency of intraoperative complications of caesareans is of 25.87% with an annual average of 51.60 (SD 5.62) cases per year, the average age of patients is 27.39 years, primiparous are the most affected with 27.44%, preoperative haemorrhages are the intraoperative complications most encountered in 74.94%, surgical repair is the most established treatment in 56.00% of cases, the maternal death rate due to intraoperative complications of caesareans is 0.32% of live births.
Conclusions: Intraoperative complications of caesarean section constitute a public health problem. Our results can serve as a basis for in-depth studies on the intraoperative complications of caesarean section in order to lower the risks associated with its practice in our environment.
The utility of colposcopy in detecting relapse after treatment of gynaecological malignancies
Authors: Joseph Anu N. , Sreedharan Sabarinath Panthrandil , Davis Nila Theresa
Published: January 2024

Background: Vaginal bleeding is the most common symptom of vault relapse in gynecological cancers. This symptom may be overlooked or attributed to other causes, such as atrophy, infection, or post-radiation changes. Colposcopy allows direct magnified visualization of vaginal mucosa and abnormal vasculature though its role in detecting relapse is unclear.
Methods: It is a retrospective observational study of 31 patients who were referred for colposcopy and biopsy with complaints of abnormal vaginal bleeding during follow up of endometrial or cervical cancer.
Results: Among 31 patients, 19 patients were diagnosed to have primary cervical cancer and 12 endometrial cancers. Primary treatment was surgery alone (n=10, 32.2%), chemo-radiation alone (n=4, 12.9%) and both (n=17, 54.8%). Abnormal colposcopic findings were atropic features (n=21, 67.7%), radiation changes (n=8, 25.8%), erosion (n=9, 29.0%), acetowhite areas (n=9, 29.0%), abnormal vessels (n=8, 25.8%) and iodine staining abnormality (n=16, 51.6%). According to Swede scoring system, 77.1% (n=24) were normal or low grade lesions, 22.6% (n=7) were high grade lesions.  Total of 6 recurrence cases identified out of which 5 cases had high grade (Swede score >7) and one had low grade (Swede score 5-7) colposcopic features. On taking Swede score cut off of 5 or more, the sensitivity of colposcopy in detecting vault recurrence is 100%, specificity 96%, positive likelihood ratio of 25%and negative likelihood ratio of 0%. Overall the accuracy of colposcopy in detecting relapse was 96.8%.
Conclusions: In our experience colposcopy is worth in detecting the cause of abnormal vaginal bleeding after treatment for endometrial and cervical cancer. Swede score is a good measure to decide on taking biopsy among these patients. Furthermore, larger studies are needed for better clarification.
Assessment of prevalence and risk factors of pre-eclampsia and eclampsia in tertiary care hospital
Authors: Tandur Anoop N. , Kuriakose Ashni , Laldinpuia Samuel K. , G. R. Nataraj , K. Lokeshwari
Published: January 2024

Background: Pre-eclampsia and eclampsia are two conditions in which high blood pressure essentially complicates pregnancy by causing oedema and/or albuminuria. The present study was undertaken among pregnant women to determine the prevalence of pre-eclampsia and eclampsia as well as to assess the association between risk factors and pre-eclampsia, risk factors and eclampsia and to determine the complications of pre-eclampsia and eclampsia.
Method: A prospective observational study was conducted over a period of six months at obstetrics inpatient department of Basaveshwara Medical college and hospital, Chitradurga.
Results: Total of 583 pregnant women who visited the inpatient department were enrolled, out of which study showed that the prevalence of pre-eclampsia was 91 (15.67%) and eclampsia was 54 (9.26%). A statistically varied significance level of p=0.00001 to 0.05 for risk factors such as age, primigravida, birth interval, pre-existing disease, placental abnormalities, multiple pregnancy, past history, proteinuria were found to be associated with pre-eclampsia and eclampsia. The complications such as pre-term birth, neonatal death HELLP syndrome (hemolysis, elevated liver enzymes, and low platelets), Foetal growth restriction were found. Out of which pre-term birth was the most observed complication in both pre-eclampsia and eclampsia.
Conclusions: Considering the significant association between the risk factors and pre-eclampsia, eclampsia from the study we conclude that early diagnosis is essential. Lack of antenatal care, limited access to medical facility and lack of resources have influenced in late diagnosis in our set up. As evidenced by study proper awareness should be provided to the pregnant women.
Fetomaternal outcome in patients with eclampsia: study in a territory care hospital in Bangladesh
Authors: Sultana Rebeka , Mondal Elaboti , Islam Robiul , Biswash Palash Kumar
Published: January 2024

Background: Eclampsia, a severe complication of preeclampsia, poses significant risks to both the mother and the fetus. Understanding the specific factors influencing these outcomes in the context of Bangladesh is crucial for improving maternal and neonatal healthcare in the region.
Methods: A retrospective cohort study was conducted at department of gynaecology and obstetrics, Jashore Medical College Hospital, Jashore, Bangladesh reviewing medical records of 155 patients diagnosed with eclampsia over a January 2020 to December 2020. Data on maternal age, gestational age, clinical presentation, management strategies, and fetal outcomes were collected and analyzed.
Results: Preliminary findings suggest that maternal age, gestational age at onset, and timely interventions play crucial roles in determining the fetomaternal outcomes in eclampsia cases. Maternal mortality rates, neonatal morbidity, and mortality rates were assessed in relation to these factors. Additionally, the study investigates the impact of various management approaches, including antihypertensive medications, and magnesium sulfate therapy on these outcomes.
Conclusions: Eclampsia continues to pose significant risks to both mothers and infants in Bangladesh. Inadequate antenatal care appears to contribute to the severity of cases. The high rate of emergency cesarean sections underscores the need for vigilant monitoring of high-risk pregnancies. Efforts to improve antenatal care utilization and implement timely interventions are crucial to mitigate the adverse fetomaternal outcomes associated with eclampsia in this setting. Further prospective studies are warranted to explore preventive strategies and optimize management protocols for better outcomes.
Neonatal birth weight as a predictor of mode of delivery in singleton term pregnancies at a tertiary level maternity hospital in Urban Mumbai
Authors: Upadhyay Dishant , Palve Tushar , Fatemi Sakina , Raza Sameen
Published: January 2024

Background: Mode of delivery is determined by a variety of feto-maternal factors like fetal presentation, maternal age, parity as well as environmental factors such as place of residence, quality of ANC care etc. Aim was to assess if neonatal birth wight (NBW) affected the mode of delivery at a tertiary level maternity hospital in urban Mumbai.
Methods: Ours was an observational study having cross sectional design, utilizing data retrieved from hospital records, conducted at Cama and Albless Hospital in Mumbai over 3 months- July 2023 -September 2023. Data regarding maternal parity, age, mode of delivery and neonatal birth weight was compiled in Microsoft Excel 2017 from hospital records after taking Ethics Committee permission for the same.
Results: In n=104 live viable term singleton pregnancies observed over 3 months LSCS rate of 25.96% was observed, higher Neonatal birth weight (NBW) was associated with caesarean delivery. 89% of the underweight neonates (<2.5kg) delivered vaginally while 100% of the macrocosmic neonates (>4kg) were delivered by LSCS. Maternal age correlated positively with neonatal weight and parity. Neonatal sex was not associated with mode of delivery or NBW.
Conclusions: Mode of delivery is affected by NBW, but not by maternal age or neonatal sex.  Mode of delivery in first pregnancy significantly determines mode of delivery in subsequent pregnancies.