bluuebunny/crossref_metadata_2025 huggingface dataset:
Phonological idiosyncrasies of the Southern Sorsogon dialect in Bulan, Philippines
Authors:   University of Negros Occidental-Recoletos, Philippines, San Jose Dominic Bryan S. , A. Pilar John Gerald
Published: August 2023

This research sought to examine the Southern Sorsogon (Sso) dialect's distinctive phonetic features in Bulan, Philippines. In the urban and rural communities of Bulan in the province of Sorsogon, six native speakers were specifically selected based on the selection criteria. The qualitative text analysis approach used in this study was based on the transcripts of in-person interviews and other contacts between the researchers and native speakers. The Sso dialect's segmental sounds and phonological characteristics were examined to unravel its phonetic characteristics. The results showed that there were four vowels with unique vowel lengths [a], [i], [u], [ʊ], fourteen consonants [b], [p], [m], [d], [t], [s], [n], [r], [l], [g], [k], [ŋ], [ʔ], [h], and two semiconsonants [w], [y]. Sounds like voiced alveolar-fricative [z], labiodental [v], [f], interdental [ð], [θ], palatal-fricative [Ʒ], [ƒ], post alveolar fricative consonant [sh], and palatal-affricate [ʤ], [tʃ] were non-existent in the Sso dialect. Other features detected were the gliding consonants, the widespread use of /r/ for further plurality, the suffix /-on/ for comparative, superlative, or exaggerations, and lexical variations for emphatic expressions and even angry registers. Although this study contributes to the documentation, preservation, and enrichment of the Sso dialect for its future in machine translation, further investigations are recommended to confirm the findings.
Representing Gandhi: A Study of Mahatma Gandhi as a Character in Selected Novels from Colonial and Post-Colonial Times
Authors:   Academic Content Researcher and Writer, Inventive Gentech Solutions, LLP: Kolkata, Gupta Mainak
Published: August 2023

The 1930s saw the rise of Mahatma Gandhi as the frontline leader of India’s struggle against the British imperialists, and it was also a decade when the Indian novel in English came of age, with the publication of Mulk Raj Anand’s Untouchable, R.K. Narayan’s Swami and Friends and Raja Rao’s Kanthapura within a few years of each other. The English novel in India grew as a consequence of the English education introduced by the British, and it was used as a weapon against the imperialists by a bunch of young men who were primarily educated abroad, with an aim to use a universal language that addressed all Indians all over the world. Gandhi, unsurprisingly, became a great source of inspiration for these writers. Gandhi has been a subject of literature and other forms of art to this day, but the portrayal of the ‘Great-soul’ (as Tagore called Gandhi) has gone through a change since the pre-independence days. This essay analyses the change in the portrayal of Gandhi by close-reading four novels, Untouchable (1935) and Kanthapura (1938) from the colonised period, and Waiting for the Mahatma (1955) and Dhorai Charit Manas (1950) from the post-independence era. The essay shows how the portrayal of Gandhi and Gandhism went through a change in the novels from the colonial period to post-colonial times, as the reverence and deification of Gandhi that was so prevalent in the novels of the colonial time gave way to a more humane portrayal of the most influential leader of India’s freedom struggle.
Types of Code-switching among Young Adults with Bilingualism
Authors:   Department of Audiology & Speech Language Pathology, SRM Medical College Hospital & Research Centre, SRM Institute of Science and Technology, Chennai-603203, Tamil Nadu, S Ruba , S Prabhu , Samayan Kala
Published: August 2023

The present study aimed to analyse and compare various forms of code-switching among adult male and female Tamil-English bilinguals. This research involved thirty bilingual (Tamil and English) adults between the ages of 18 and 25. Each participant was given an updated version of the cookie-theft picture and asked to describe it in Tamil. The various kinds of code-switching, such as tag switching, intra-sentential switching, and inter-sentential switching, were identified through the data analysis. Results indicated that language switching occurs more frequently between phrases and that female participants exhibit code-switching significantly higher than male participants, particularly in tag switching. The study findings can help linguists and speech-language pathologists understand the various types of code-switching employed by Tamil-English bilinguals. However, a larger population needs to be studied for further investigation.
Zoneamento e avaliação da severidade das estiagens entre os anos de 1961 até 2019 na Bacia Hidrográfica do Rio São Francisco com base em valores do Índice de Precipitação Padronizado
Authors: Silva Ana Carine , Fabio Farias Pereira
Published: August 2023

Esta pesquisa buscou determinar a severidade das estiagens na Bacia Hidrográfica do Rio São Francisco, bem como mapear as áreas de estiagens, e determinar se as áreas com estiagens mais severas estão distribuídas ao longo da Bacia ou se estão concentradas em um único ponto. Para a determinação da severidade das secas foi utilizado o Índice de Precipitação Padronizado (SPI). Foram utilizados os dados de precipitação das estações pluviométricas, do banco de dados do Instituto Nacional de Meteorologia (INMET). Para a realização do cálculo do índice de estiagem, foi utilizado um software de linguagem de programação. Os resultados desta pesquisa mostraram que embora a região do Alto São Francisco possua valores elevados de precipitação acumulada, ela se destaca quanto ao SPI3, secas de curto prazo, de forma contrária no Baixo São Francisco, que mostrou menores incidências de secas de curto prazo. De modo que as secas de longa duração, relacionadas ao SPI 12 e SPI24 foram observadas no Submédio e Médio São Francisco. Através da Análise de Cluster foi verificada a existência de similaridade entres postos pluviométricos alocados dentro de regiões distintas da bacia quando observadas nos parâmetros das variáveis da seca.
Teria Habermas recorrido a uma suposição dworkiana equivocada em die zukunft der menschlichen natur?
Authors: Feldhaus Charles
Published: August 2023

.
New Pyrrolopyrimidines as LRRK2 Inhibitors for Treating Parkinson's Disease
Authors: De Surya K.
Published: August 2023

:

This patent describes the novel pyrroloppyrimidine compounds as LRRK2 kinase
inhibitors. The patent includes the synthesis of compounds, compositions containing
them and their use in the treatment of or prevention of diseases associated with LRRK2
kinase activity, such as Parkinson's disease, Alzheimer's disease, and amyotrophic lateral
sclerosis (ALS).
Identifying Oxidative Stress-Related Genes (OSRGs) as Potential Target
for Treating Periodontitis Based on Bioinformatics Analysis
Authors: Zhou Wei , Zhang Pengfei , li Hao
Published: August 2023

Background:

Periodontitis (PD) is a multifactorial inflammatory disease that is closely
associated with periodontopathic bacteria. Numerous studies have demonstrated oxidative stress
(OS) contributes to inflammation and is a prime factor in the development of PD. It is imperative
to explore the function of newly discovered hub genes associated with OS in the advancement of
PD, thereby identifying potential targets for therapeutic intervention.

Objectives:

The goal of the current study was to identify the oxidative-stress-related genes (OSRGs)
associated with periodontitis (PD) development using an integrated bioinformatics method.

Methods:

DEGs from GEO gene-expression data were identified using the "limma" package. We
obtained OSRGs from GeneCards and utilized a Venn diagram to uncover differentially expressed
OSRGs (DEOSRGs). After receiving the DEOSRGs, we employed Gene Ontology (GO), Kyoto
Encyclopaedia of Genes and Genomes (KEGG), and protein-protein interaction (PPI) analytical
tools to examine their possible functions and pathways in PD. Receiver operating characteristic
(ROC) curves screened for hub genes of PD. RT-qPCR and western blot analysis were used to detect
DEOSRG expression in mouse ligature-induced periodontitis gingival tissues.

Results:

The investigation identified 273 OSRGs. Based on PPI analysis, we recognized 20
OSRGs as hub genes. GO and KEGG enrichment analysis indicated that these hub genes were predominantly
enriched in leukocyte migration, lymphocyte proliferation, and humoral immune response,
and associated with leukocyte trans-endothelial migration, cytokine-cytokine receptor interaction,
and NF-κB signaling pathway. Following ROC analysis, VCAM1, ITGAM, FCGR3A,
IL1A, PECAM1, and VCAM1were identified as PD prognostic gene. RT-qPCR and western blot
analyses confirmed that the expression ITGAM, FCGR3A, and PECAM1 were significantly
elevated in the gingival tissues obtained from mice.

Conclusion:

This investigation revealed that ITGAM, FCGR3A, and PECAM1 may have a crucial
function in the advancement of PD.
Towards the Integrative Theory of Alzheimer’s Disease: Linking Molecular
Mechanisms of Neurotoxicity, Beta-amyloid Biomarkers, and the Diagnosis
Authors: Molkov Yaroslav I. , Zaretskaia Maria V. , Zaretsky Dmitry V.
Published: August 2023

Introduction:

A major gap in amyloid-centric theories of Alzheimer’s disease (AD) is that
even though amyloid fibrils per se are not toxic in vitro, the diagnosis of AD clearly correlates with the
density of beta-amyloid (Aβ) deposits. Based on our proposed amyloid degradation toxicity hypothesis,
we developed a mathematical model explaining this discrepancy. It suggests that cytotoxicity depends
on the cellular uptake of soluble Aβ rather than on the presence of amyloid aggregates. The dynamics
of soluble beta-amyloid in the cerebrospinal fluid (CSF) and the density of Aβ deposits is described
using a system of differential equations. In the model, cytotoxic damage is proportional to the
cellular uptake of Aβ, while the probability of an AD diagnosis is defined by the Aβ cytotoxicity accumulated
over the duration of the disease. After uptake, Aβ is concentrated intralysosomally, promoting
the formation of fibrillation seeds inside cells. These seeds cannot be digested and are either accumulated
intracellularly or exocytosed. Aβ starts aggregating on the extracellular seeds and, therefore,
decreases in concentration in the interstitial fluid. The dependence of both Aβ toxicity and aggregation
on the same process−cellular uptake of Aβ−explains the correlation between AD diagnosis and the
density of amyloid aggregates in the brain.

Methods:

We tested the model using clinical data obtained from the Alzheimer’s Disease Neuroimaging
Initiative (ADNI), which included records of beta-amyloid concentration in the cerebrospinal fluid
(CSF-Aβ42) and the density of beta-amyloid deposits measured using positron emission tomography
(PET). The model predicts the probability of AD diagnosis as a function of CSF-Aβ42 and PET and
fits the experimental data at the 95% confidence level.

Results:

Our study shows that existing clinical data allows for the inference of kinetic parameters describing
beta-amyloid turnover and disease progression. Each combination of CSF-Aβ42 and PET values
can be used to calculate the individual’s cellular uptake rate, the effective disease duration, and the
accumulated toxicity. We show that natural limitations on these parameters explain the characteristic
distribution of the clinical dataset for these two biomarkers in the population.

Conclusion:

The resulting mathematical model interprets the positive correlation between the density
of Aβ deposits and the probability of an AD diagnosis without assuming any cytotoxicity of the aggregated
beta-amyloid. To the best of our knowledge, this model is the first to mechanistically explain the
negative correlation between the concentration of Aβ42 in the CSF and the probability of an AD diagnosis.
Finally, based on the amyloid degradation toxicity hypothesis and the insights provided by
mathematical modeling, we propose new pathophysiology-relevant biomarkers to diagnose and predict
AD.
One-pot Multicomponent Reaction: An Efficient Synthesis of
4-(Het)Aryl-substituted Pyrazolo-quinolinones
Authors: Beker Hüseyin Kerim , Kaban Şeniz
Published: August 2023

Introduction:

Pyrazolo-quinolinones (PQs) are a versatile class of Organic chemistry and it was found that they have very advanced functionally promising as selective compounds due to their scaffold and demonstrated low toxicity and considerable clinical promise. Moreover, these compounds have an important role in different applications such as analytical reagents, technical, pharmaceutical development, and biological markers. So, we aimed to synthesize and characterize new 4-(Het)aryl-substituted Pyrazole-quinolinones.

Methods:

Synthesis of One-Pot Multicomponent Reaction was carried out with the reaction of 5-amino-3-methyl-1H-pyrazole 1a, and 5-amino-3-phenyl-1H-pyrazole 1b and dimedone 2 with some (het)aryl aldehydes 3 using ethanol. Characterizations such as the linear structures and the regiospecificity of the reactions were determined by using NMR, GC-MS, IR, and UV measurements.

Conclusion:

This research will be very useful for all methods and procedures using multi-one-point reactions which are very popular in the synthesis of heterocyclic systems for pyrazole- quinoline skeleton synthesis.
Anti-inflammatory Alkaloids Targeting IL-1 against Respiratory Viral Infections: A Special Insight into Drug Development against SARS-CoV-2
Authors: Batool Salma , Asim Laiba , Zhang Jin , Qureshi Fawad Raffaq , Saleem Rahman Shah Zaib
Published: August 2023

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is one of the deadliest
viruses among respiratory viruses which resulted in COVID-19 pandemic. The virus gets transmitted
by the nasal route and moves down to the trachea, bronchi, and then to the lungs. Once replicated inside
the alveolar cells, the SARS-CoV-2 makes the membrane of the alveolar sac porous, which causes
the leaking of plasma from surrounding blood vessels into the alveolar sac leading to its buildup. This
process results in the production of pro-inflammatory cytokines like interleukin-1β (IL-1β) and Tumor
necrosis factor-α (TNF-α) by the helper T-cells at the site of the infection, causing difficulty in breathing.
Plant-based alkaloids can be promising to treat viral infections. Plants have contributed to drug
development against viruses like Herpes simplex virus (HSV), Human immunodeficiency virus (HIV),
Hepatitis B virus (HBV), and viruses that cause respiratory diseases in humans. Plant alkaloids, either
in the form of extract, infusion, or powder, have shown potential in treating viral diseases mainly by
targeting the replication of viruses. Alkaloids like Tetrandrine, Oxymatrine, and Berberine have been
shown to have a positive role in mediating pro-inflammatory cytokines like IL-1. These alkaloids thus
inactivate the nuclear factor kappa-B (NF-kB) pathway, inhibiting the expression of its targeted genes,
IL-1β and TNF-α. This inactivation of NF-kB results in reduced levels of IL-1 and TNF-α, and consequently
reduced inflammation, decreasing the stress on the immune cells and increasing the ability of
the patient to fight the infection. Despite vaccine development for SARS-CoV-2, the virus is continuously
evolving into new varieties, posing a threat to humans and it is necessary to develop effective
drug discovery programs. Natural products can pave the way in this regard. This review can contribute
towards safer drug development against SARS-CoV-2, combating the threat of the ever-emerging variants
of this virus.
An updated Review on Flaxseed Mucilage (Linum Usitatissimum) Extraction Methods and its Food Applications
Authors: Wal Ankita , Wal Pranay , Gupta Arpit , Morris Srishti , Sahu Kantrol Kumar
Published: August 2023

Flaxseed (Linum usitatissimum) has become well recognised as a health food due to its richness in various bioactive substances & nutrients such as lignans, fibres, oil, mucilage, fatty acids, carbohydrates, proteins, micronutrients, and peptides. These elements endow flaxseed with a wide range of beneficial properties that allow it to be used as nutritional supplements or as ingredients in functional beverages and in the food industry. In this review, the nutritional value of flaxseed (Linum usitatissimum) along with its mucilage extraction methods and food applications are described. A comprehensive analysis of the literature search was conducted. A number of databases have been searched using the common terms “Flaxseed”, “Lignans”, “Linum usitatissimum”, “Phytochemicals”, “Food”, and “Functional claim” using PubMed and Google Scholar as search engines. The content was based on information from publications like Springer nature, Hindawi, Elsevier, MDPI, Bentham science, Taylor and Francis, etc. In this review paper we have done an exhaustive analysis of more than 80 review articles, research papers, comprehensive reviews, and case studies published between 1984-2023.
Flaxseed has a nutritional makeup that can be good for your health. Many people remain unaware of the possible numerous medical advantages of flaxseed and its uses in food preparation. Flaxseed is the finest food source for lignans and linolenic acid. The potential for it to serve as a source of soluble fibre, anti-oxidants, and protein of excellent quality is also very high. As a result, it is suggested to use flaxseed as a dietary supplement in whole or ground form.
One of the possible oil seeds is flax, which is rich in nutrients and has a number of health advantages. It's interesting to note that the fibre, lignans, & omega-3 fatty acids found in flax seeds are mostly responsible for their health advantages. Due to its low saturated fat, high Poly-unsaturated fatty acids (PUFA), and phytosterol content, consumption of this oil seed could reduce total as well as Low-density-lipoprotein (LDL) cholesterol. Flax seeds are processed to make their nutrients more bioavailable.
Machine Learning Algorithms Identify Target Genes and the Molecular
Mechanism of Matrine against Diffuse Large B-cell Lymphoma
Authors: Zhu Yidong , Ning Zhongping , Li Ximing , Lin Zhikang
Published: August 2023

Background:

Diffuse large B-cell lymphoma (DLBCL) is the most common type
of non-Hodgkin's lymphoma worldwide. Novel treatment strategies are still needed for this
disease.

Objective:

The present study aimed to systematically explore the potential targets and molecular
mechanisms of matrine in the treatment of DLBCL.

Methods:

Potential matrine targets were collected from multiple platforms. Microarray data and
clinical characteristics of DLBCL were downloaded from publicly available database. Differential
expression analysis and weighted gene co-expression network analysis (WGCNA) were applied to
identify the hub genes of DLBCL using R software. Then, the shared target genes between
matrine and DLBCL were identified as the potential targets of matrine against DLBCL. The least
absolute shrinkage and selection operator (LASSO) algorithm was used to determine the final
core target genes, which were further verified by molecular docking simulation and receiver operating
characteristic (ROC) curve analysis. Functional analysis was also performed to elucidate the
potential mechanisms.

Results:

A total of 222 matrine target genes and 1269 DLBCL hub genes were obtained through
multiple databases and machine learning algorithms. From the nine shared target genes of matrine
and DLBCL, five final core target genes, including CTSL, NR1H2, PDPK1, MDM2, and JAK3,
were identified. Molecular docking showed that the binding of matrine to the core genes was stable.
ROC curves also suggested close associations between the core genes and DLBCL. Additionally,
functional analysis showed that the therapeutic effect of matrine against DLBCL may be
related to the PI3K-Akt signaling pathway.

Conclusion:

Matrine may target five genes and the PI3K-Akt signaling pathway in DLBCL treatment.
Replacement Dose for Overt Hypothyroidism Induced by Programmed
Cell Death Protein 1 Antibodies May Be Higher than Recommended
Authors: Zhang Qian , Zhang Yao , Zhu Huijuan , Liu Kuanzhi , Lou Pingping , Kong Peixuan , Su Lei , Wang Shuchang
Published: August 2023

Background:

The present recommendations, consensus, or guidelines for the replacement
dosage for hypothyroidism induced by programmed cell death protein 1 (PD-1) therapy are
not uniform, and there are very few special clinical trials that have examined the replacement dosage
for it.

Objectives:

This article illustrates the clinical characteristics of hypothyroidism induced by PD-1
antibodies (Abs) and reports the recommended replacement dosage for hypothyroidism.

Methods:

Eighteen patients with overt primary hypothyroidism induced by PD-1 Abs (group 1)
were selected from 655 patients with different tumor types. Retrospective analysis was performed
on patients in group 1 and 18 patients with natural courses of overt primary hypothyroidism who
were age- and sex-matched with the patients in group 1 (group 2). The replacement dosages required
for the patients in the two groups were compared.

Results:

Thyroid dysfunction occurred in group 1 after approximately 3.0 ± 1.4 cycles of PD-1
therapy (1-6 stages), with a median time of 61.5 days. The median time of onset of hypothyroidism
among all patients was 87.5 days (30-240 days). Most of the patients with hypothyroidism were
asymptomatic, and the onset of hypothyroidism was independent of age, sex, TPOAb, TgAb and
TSH in group 1 (P>0.05). The average replacement dosage for patients in group 1 was 1.8 ± 0.6
μg/kg/d (0.6-3.2 μg/kg/d). Multiple linear regression analysis showed that sex, age, TPOAb, TgAb
and TSH were not correlated with drug dosage.

Conclusion:

It seemed that the average maintenance dosage of levothyroxine might need to be 1.8
μg/kg/day for patients with overt hypothyroidism induced by PD-1 Abs.
In-situ Gelling Platform for Ocular Drug Delivery System: A New Paradigm
Authors: Shadab Sumbul , Alam Md. Aftab , Sharma Pramod Kumar , Paliwal Deepika
Published: August 2023

One of the most promising novel drug delivery systems is an In-situ gel, which uses a
unique 'Sol to Gel' conversion to help with the slow and steady release of pharmaceuticals. An insitu
gel system enters the body as a solution but transforms into a gel once it encounters the
body's internal environment. Traditional methods of ocular drug delivery, such as suspensions,
eye drops, and ointments, have a number of drawbacks. These include lacrimation, obscured vision,
and, most importantly, rapid precorneal clearance. As a result, many innovative methods
have been created in order to address these shortcomings. In-situ gel, minidisc, ocusert, nanosuspension,
collagen shield, nanoparticulate, system, niosomes, ocular iontophoresis, liposome, ocular
film, dendrimers, and other methods are among them. Ocular medication delivery systems
have come a long way recently, and one of the most recent innovations is In-situ ocular gel. The
polymers (natural, semisynthetic, or synthetic) that make up the In-situ ocular gel system's delivery
vehicle have the unique feature of a sol-gel transition when subjected to the effect of a biological
stimulus, such as a change in temperature, pH, or ions. Physical appearance, clarity, pH, gelling
ability, isotonicity evaluation, sterility, viscosity, In vitro drug release, and irritancy tests are
all investigated in In-situ ocular gels.
WITHDRAWN: A Densification Prediction Model of Selective Laser Melting Based on BP Neural Network
Authors: Qian Bin , Pan Lu , Wang Yaqin , Liu Xinyu , Jiang Hua , Wang Liang
Published: August 2023

Since the authors are not responding to the editor’s requests to fulfill the editorial requirement, therefore, the article has been
withdrawn.

Bentham Science apologizes to the readers of the journal for any inconvenience this may have caused.

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Deep SLRT: The Development of Deep Learning based Multilingual and Multimodal Sign Language Recognition and Translation Framework
Authors: Balasubramanian Natarajan , Rajasekar Elakkiya
Published: August 2023

Developing deep neural models for continuous recognition of sign gestures
and generation of sign videos from spoken sentences is still challenging and requires
much investigation in earlier studies. Although the recent approaches provide plausible
solutions for these tasks, they still fail to perform well in handling continuous sentences
and visual quality aspects. The recent advancements in deep learning techniques
envisioned new milestones in handling such complex tasks and producing impressive
results. This paper proposes novel approaches to develop a deep neural framework for
recognizing multilingual sign datasets and multimodal sign gestures. In addition to that,
the proposed model generates sign gesture videos from spoken sentences. In the first
fold, it deals with the sign gesture recognition tasks using a hybrid CNN-LSTM
algorithm. The second fold uses the hybrid NMT-GAN techniques to produce high quality sign gesture videos. The proposed model has been evaluated using different
quality metrics. We also compared the proposed model performance qualitatively using
different benchmark sign language datasets. The proposed model achieves 98%
classification accuracy and improved video quality in sign language recognition and
video generation tasks.
Knowledge Graphs for Explaination of Black-Box Recommender System
Authors: Gupta Mayank , Saini Poonam
Published: August 2023

Machine learning models, particularly black-box, make powerful decisions
and recommendations. However, these models lack transparency and hence cannot be
explained directly. The respective decisions need explanation with the help of
techniques to gain users' trust and ensure the correct interpretation of a particular
recommendation. Nowadays, Knowledge graphs (K-graph) has been recognized as a
powerful tool to generate explanations for the predictions or decisions of black-box
models. The explainability of the machine learning models enhances transparency
between the user and the model. Further, this could result in better decision support
systems, improvised recommender systems, and optimal predictive models.
Unfortunately, while these black box devices have no detail on the reasons behind their
forecasts, they lack clarity. White box structures, on the other hand, will quickly
produce interpretations due to their existence. The chapter presents an exhaustive
review and step-by-step description for using knowledge graphs in generating
explanations for black-box recommender systems, which further helps in generating
more persuasive and personalized explanations for the recommended items. We also
implement a case study on the MovieLens dataset and WikiData using K-graph to
generate accurate explanations.
Digital marketing strategy for business services
Authors: Murti Aji Kresno , Endrawati Titin , Kurniawan Muhammad Sani , Sutjiatmo Bayu Prabowo , Wicaksono A. R. Arie
Published: August 2023

This study delves into the significance of digital marketing strategies for business services, specifically within the financial services sector. Using a literature research method to examine the marketing challenges of the financial service companies under investigation, which leads to the formulation of new digital marketing strategies. The recommended digital marketing strategy centers on social media marketing, search engine optimization, and email marketing, with an emphasis on personalization and robust customer engagement. Findings underscore the essential role of digital marketing, especially in the competitive financial services industry. Anticipated outcomes encompass heightened customer engagement, increased brand awareness, and amplified revenue generation. The study highlights challenges like skilled personnel requirements and data privacy concerns, along with the importance of gauging digital marketing effectiveness. By offering practical insights, the research equips business services firms to cultivate and implement effective digital marketing strategies. Ultimately, this study underscores the paramountcy of digital marketing strategies in business services and presents a pragmatic framework for their integration.
Determination of Pollutant Index (PI) for Assessing the Quality of Groundwater in the Area of Sidoarjo Mud (LUSI) Sidoarjo, East Java, Indonesia
Authors:   Tomsk Polytechnic University, Adiyaksa Ilham Putra , Savichev Oleg G. ,   Tomsk Polytechnic University
Published: August 2023

Sidoarjo mud (well known as LUSI) have been occurred since 2006 in Sidoarjo, East Java, Indonesia and gives many impacts to many aspects, as well as environment and water quality condition. One of the major concerns is water quality problem, especially in this current situation in 2022 since clean water still needed by local people and groundwater is the main water source for many local people in this area. Our previous study has carried out to assess the ecological and geochemical conditions of groundwater in the area around Sidoarjo mud in 2022. In this study, by using Pollutant Index (PI) calculation, the water quality classification will be determined from several samples and parameters in various places, including Tanggulangin, and Porong, Sidoarjo, East Java. From the calculation result, based on Pollution Index (PI) value, water in Tanggulangin is categorized as good water (clean water), while water in Porong is categorized as good water (clean) as well for sample B3, and the rest is categorized as lightly polluted water with sample B5 as the most contaminated. Groundwater in the area near to Sidoarjo mud is contaminated by NO2-, Mn, and Hg.
Analiza struktury oferowania rozkładowych linii lotniczych w krajach Europy Środkowej Część pierwsza
Authors: Serafin Marek
Published: August 2023

Okres postpandemiczny jest szczególnie ważny dla europejskiego rynku lotniczego. Możemy obserwować nowe trendy zmian, które będą go kształtowały przez kolejnych wiele lat. Widzimy już wyraźnie, że region Europy Środkowej ma swoją specyfikę, odróżniającą go od Europy Zachodniej. W przypadku naszego kraju analizowanie sytuacji i prognozowanie przyszłości jest szczególnie ważne, gdyż podejmowane są obecnie decyzje dotyczące ogromnych inwestycji infrastrukturalnych. Struktura liczby oferowanych przez rozkładowe linie lotnicze foteli oraz zmiany w niej zachodzące są bardzo dobrymi indykatorami strategii przewoźników lotniczych, najważniejszych uczestników gry rynkowej. Słowa kluczowe: oferowanie, przewoźnicy sieciowi, tanie linie, trendy zmian
Rewitalizacja w polityce rozwoju województwa mazowieckiego na tle uwarunkowań krajowych i unijnych – doświadczenia i perspektywy
Authors: Kucharska Agata , Piwowarczyk Dariusz
Published: August 2023

W artykule przeanalizowano prowadzoną od blisko 25 lat politykę rozwoju województwa w zakresie rewitalizacji, wyrażoną w dokumentach strategicznych i planistycznych poziomu regionalnego, w kontekście zmieniających się uwarunkowań krajowych i unijnej polityki spójności. Ponadto zbadano rolę Samorządu Województwa Mazowieckiego we wdrażaniu środków unijnych na działania rewitalizacyjne w ramach Zintegrowanego Programu Operacyjnego Rozwoju Regionalnego 2004–2006 oraz dwóch edycji Regionalnego programu operacyjnego województwa mazowieckiego: 2007–2013 i 2014–2020. Przedstawiono również zestawienie środków Europejskiego Funduszu Rozwoju Regionalnego wydatkowanych na projekty rewitalizacyjne w ramach powyższych programów. Dodatkowo przeanalizowano działania komplementarne i uzupełniające do rewitalizacji na obszarach wiejskich w zakresie odnowy wsi, wdrażane przez samorząd województwa w ramach programów krajowych: Sektorowego Programu Operacyjnego – Restrukturyzacja i modernizacja sektora żywnościowego i rozwój obszarów wiejskich 2004–2006 oraz dwóch edycji Programu Rozwoju Obszarów Wiejskich: 2007–2013 i 2014–2020. Słowa kluczowe: rewitalizacja, polityka rozwoju, województwo mazowieckie, regionalne programy operacyjne, dofinansowanie UE
Modern Low-Magnitude Earthquake Swarms of the Gakkel Mid-Oceanic Ridge, Arctic Ocean
Authors: Morozov Aleksey , Vaganova Natalia , Starkov Ivan , Mikhaylova Yana
Published: August 2023

Earthquakes at mid-ocean ridges (MOR) reflect the active magmatic and tectonic processes that form new oceanic crust. Active spreading processes of ultraslow ridges, with spreading rates of less than 20 mm/yr, are still poorly understood compared to the MOR in the Atlantic and Pacific oceans, with spreading rates of more than 25 mm/yr. Thanks to the installation of stationary seismic stations in the 21st century on the Arctic archipelagos of Franz Josef Land and Severnaya Zemlya, it became possible to record and study low-magnitude grouping earthquakes within the Gakkel Ridge, including swarm sequences of earthquakes. This article presents the first results of registration, location and study of swarm sequences of low-magnitude earthquakes within the Gakkel Ridge for the period from 2012 to 2022. It is shown that swarm sequences are recorded to a greater extent in the western volcanic and eastern volcanic segments of the ridge, while no such sequences were found within the central amagmatic segment. The structure formation of this part of the ridge is dominated by tectonic rather than magmatic and metamorphic processes. Two large swarm of low-magnitude earthquakes that occurred in the eastern volcanic segment of the ridge are considered in detail.
Colonial Struggle-Revolt of Adivasis against Corporate Policies and It’s Invisibility in Modern Global Fictions of Indian English Literature
Authors: Madavi Dr. Manoj Shankarrao
Published: August 2023

The treatment to the adivasi community in Postcolonial Indian English fiction lacks in many grounds. Tribal historical revolts, encroachments of British rule into tribal territories, grabbing lands of the tribals, exploitation of tribal women, cruel landlords, deforestation and degradation of tribal environmental values do not find realistic representation in Indian English fictions. In Gita Mehta's The River Sutra, tribal are shown as the worshipper of Narmada River and performing some ritual on the bank of River Narmada, but tribal religious concerns are not so much the limited and full of superstitions. They consider land, forest and water as godly gift to them. In fact these natural objects are itself Godlike for them but when British power and landlords took the illegal entry in their territories, they protested against them and became the epitome of valor and martyrdom in the history. This research article tries to examine the bias attitude of mainstreams literature writing regarding the adivasi heritage and glorious tradition of revolt and sacrifice.
La neutralidad en los análisis sociohistóricos de los sistemas sociales humanos
Authors: Díaz Miguel Pedro
Published: August 2023

En el presente artículo se considera que la ciencia es realizada dentro de determinados sistemas sociales y que estos pueden imprimir algún matiz particular a los análisis. Tener presente la posibilidad de dichos inconvenientes, analizados desde el prisma teórico de la Sociología del conocimiento, puede facilitar la objetividad de los estudios que se lleven a cabo. No obstante, se estima que la ciencia y su método siguen siendo la mejor forma de analizar los sistemas sociales generados por los humanos.
Monitoreo a largo plazo de yaguareté (Panthera onca) en la Reserva Natural de la Defensa Puerto Península, Argentina, un área clave para esta especie
Authors: Gantchoff Mariela , Lodeiro Ocampo Nicolás , Nigro Norberto Angel , Martínez Guillermo D. , Musto Eduardo E. , Faifer Luis M. , Hultgren Mauro
Published: August 2023

La Reserva Natural de la Defensa Puerto Península, en el departamento Iguazú, provincia de Misiones, Argentina, alberga alrededor de 8,800 hectáreas de ambientes de Selva Paranaense o Bosque Atlántico del Alto Paraná en buen estado de conservación. Entre 2016 y 2022, mediante un monitoreo sostenido con cámaras trampa, documentamos al menos 15 individuos de yaguareté (tres hembras, ocho machos y cuatro de sexo no identificado), residentes y transeúntes. El 40% de los individuos fue registrado también en áreas protegidas vecinas en Argentina y Brasil. Sugerimos que se trata de un sitio de alta importancia para la conservación de la especie que ya ha perdido casi el 70% de su superficie original. A pesar de no ser de gran tamaño, esta reserva natural parece ser clave para la conectividad a nivel paisaje del yaguareté. Es necesario garantizar su permanencia a largo plazo y evitar nuevas pérdidas de territorio.
High Speed Network Design for Health Care Application Services via Cloud based Services
Authors: R L Hemanth Kumar , N Varsha , Nagaraja G S
Published: August 2023

Abstract: This paper presents a design for high-speed networks for healthcare application activities and services via cloud-based services using Cisco Packet Tracer. The design includes a network topology that incorporates various healthcare applications such as telemedicine, electronic health records, medical imaging, and remote patient monitoring. We utilize Cisco Packet Tracer to simulate the network and evaluate its performance under different traffic loads and network conditions. The proposed network design takes into account key factors such as low latency, high throughput, and reliability, and includes techniques such as traffic engineering, QoS, and load balancing to optimize network performance. Our aim is to provide a practical implementation of high-speed networks for healthcare services using Cisco Packet Tracer, and to help healthcare organizations make informed decisions about network design for their cloud-based healthcare services.
The Effect of Classes Using the Math Story Program on Mathematical Creativity and Mathematical Interest
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, An Jong Su
Published: August 2023

Objectives This study was to enhance mathematical creativity and mathematical interest through the Math story program suitable for first-year high school classes. First, the purpose of this study based on the necessity of the above research is to create an environment to apply the Math story program. Second, the Math Stroy program was designed and applied. Third, it is to enhance students' mathematical creativity and mathematical interest by applying educational activities related to the Math story program activities to school classrooms.
Methods The researcher was working at 00 High School located in 00 Metropolitan City. The study was conducted on 56 students in two classes in the first grade of this school. Two classes were selected based on the results of the midterm exam in the second semester of the first grade. Class 1 was divided into experimental classes and class 1 was divided into control classes. The study period was from October 11 to December 12, 2022, and 13 classes were conducted for about 2 months. The experimental class (32 students) was taught using the Math story program, and the control class (32 students) was taught focusing on traditional textbooks and teacher guidance books. The experimental class and the control class conducted different learning activities, but the learning content and guidance content were taught at the same level.
Results In this study, the following results were obtained. First, in this study, the learning contents for each unit were first set and classes were conducted using the Math story program. By applying this to the class, mathematical creativity and mathematical interest could be enhanced. Second, classes using the Math story program were more effective in mathematical creativity and mathematical interest compared to traditional textbooks and teacher guidance-oriented classes for students in the upper, middle, and lower ranks. Third, in classes using the Math story program, low-ranking students, who have usually been ignored in math classes, also became interested in the class, showing improvement in mathematical creativity and mathematical interest.
Conclusions In conclusion, the experimental class taught using the Math story program was more effective in mathematical creativity and mathematical interest than the control class.
Research Trends in Mentoring Programs for Nursing Students in Korea
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Park cho-long
Published: August 2023

Objectives The purpose of this study is to identify effective mentoring program composition, methods, and strategies by analyzing research trends on mentoring programs applied to nursing students in Korea.
Methods Literature collection was searched in 5 domestic electronic databases (National Assembly Library, RISS, DBpia, KISS, NDSL). There is no limit to the year of the thesis publication, (‘mentoring’ OR ‘mentoring program’ OR ‘mentorship’) AND (‘nursing student’ OR ‘nursing college student’ OR ‘student nurse’) researcher searched and refined. As a result, a total of 75 articles were searched, and 10 articles that met the selection criteria were analyzed.
Results The papers analyzed were 10 papers in domestic academic journals, 7 papers (70%) included in Korean Citation Index (KCI), and 3 papers (30%) in KCI candidate papers. The study design consisted of 9 quantitative studies (90%) and 1 mixed study (10%). The composition of the mentoring program varied according to the purpose, and the main variables and application effects of the mentoring program were career development, major satisfaction, improved adaptation to college life, clinical performance ability, self-esteem, self-confidence in nursing practice, and self-leadership. It has been shown to have a positive effect on adaptation, development, and ego.
Conclusions This study identifies the research trends of mentoring programs for nursing students in Korea, identifies the characteristics of mentoring programs, key variables, and application effects, thereby identifying the need for periodic retraining and application, the main aspects to be considered when evaluating the effectiveness of mentees and mentors, and more. Furthermore, it provides insight into future research directions for the development of effective mentoring program methods and strategies tailored to the era of the 4th industrial revolution centered on learners.
Studi Komparatif Sikap Ta’dzim Santri Antara Dayah Tradisional dan Modern di Aceh
Authors: Alimuddin
Published: August 2023

This research is motivated by the decline in morals and the increasingly rare attitude of respect for students to their teachers who are suspected of current public education institutions failing to shape the morals of their students. However, on the other hand, dayah educational institutions are still consistently producing generations of knowledge and noble character, one of which is respect. Furthermore, glorify (ta'dzim) to (parents, teachers, etc.). However, each of the traditional and modern dayahs has its way of instilling the moral values/ta'dzim attitude, and this is because the two have different learning systems/patterns. The purpose of this study was to describe the form of teaching and practice of santri ta'dzim attitudes in traditional and modern dayahs and the similarities and differences between the two. This research was conducted by field study using the descriptive qualitative method with data collection techniques in literature study, interviews, observation and documentation. The results showed that the teaching/ method of fostering ta'dzim attitudes at the Thalibul Huda and Modern Darul 'Ulum YPUI Banda Aceh schools by using reading books, lectures, advice and guidance methods, while in practice, in both dayahs they had a ta'dzim attitude to the teachers (Tengku/ustadz). or the leader of the dayah in the form of speaking or conveying something politely and courteously. In daily activities, when the teacher explains the lesson or speaks, the students listen and do not argue or show an attitude that does not please the teacher.
Pengembangan Karakter Siswa Melalui Kegiatan Ekstrakurikuler di SLTA Kota Banda Aceh
Authors: Munzahri
Published: August 2023

Extracurricular activities are learning activities that are held outside of class hours which are arranged with the need for knowledge, development, guidance and habituation of students to have basic supporting knowledge. The purpose of this study was to determine the implementation of character development through religious extracurricular activities and to determine the supporting and inhibiting factors of character development through religious extracurricular activities in Banda Aceh City Senior High School. This research was conducted with a field study using a qualitative descriptive method. Data collection techniques were carried out through interviews and documentation. From the research conducted by the researcher, the results obtained are that the implementation of character development through religious extracurricular activities held by the Banda Aceh City Senior High School is praying together and reading yasin, zuhur prayer obligatory in congregation, reading and writing program of the Qur'an, activities Islamic holidays, sharing Friday programs. The supporting factors for character development through religious extracurricular activities include support from teachers and school principals as well as enthusiasm from school residents, and adequate facilities and infrastructure, while obstacles in these activities of course exist such as there are still some students who do not take part in these activities and also some facilities. inadequate infrastructure if there are larger activities such as isra' mi'raj and the commemoration of the Prophet's birthday.
Relevansi Teori Multiple Intellegences dengan Undang-Undang Sistem Pendidikan Nasional Tahun 2003
Authors: Almunadi Mufrih , Azhar Azhar
Published: August 2023

Howard Gardner's idea about the existence of multiple intelligences or multiple intelligences which he outlined in his book "Frames of Mind" has changed the perspective of many people in studying human intelligence. To recognize and develop all the intelligences possessed by each student which varies greatly and all combinations of these intelligences the state has an important role to play, including in formulating various policies in education laws. However, in Indonesia, there are still many teachers who often do not provide opportunities and opportunities for their students to develop their multiple intelligences through suitable learning strategies and methods. One of the factors that may underlie this is the absence of mention of the theory of multiple intelligences in the Indonesian National Education System Law or the 2003 National Education System Law. In this study the authors wish to examine the relevance of the theory of multiple intelligences to the 2003 National Education System Law. This research is a qualitative research that can be categorized as library research. The results of this study explain that there is some relevance between the theory of multiple intelligences and the 2003 National Education System Law.