bluuebunny/crossref_metadata_2025 huggingface dataset:
Um estudo sobre a construção da identidade docente
Authors: Cruz Clériston Jesus da
Published: September 2021

O presente artigo tem por objetivo discutir alguns dos fatores que auxiliam na construção da identidade docente. Tais fatores se encontram nos trilhos sócio-históricos, profissionais e cognitivos da sociedade, formando e reformando a práxis educativa num processo de constante transformação e evolução. Para mais, o artigo busca compreender como os diferentes fatores interferem nas identidades dos profissionais que se encontram nas salas de aulas, de tal modo que suas práticas sejam alteradas ao decorrer de suas vidas profissionais. Como embasamento teórico, foram utilizados os estudos de Freire (2011), Ciampa (1984), Dubar (1997), Hall (2005), Bauman (2005), entre outros, que dizem respeito à construção da identidade. Logo, conclui-se que a cultura, a moral e a ética, estabelecidas em uma sociedade, na qual o sujeito está inserido, inferem nas identidades dos indivíduos. De igual modo, a globalização em comunhão com a economia, também contribuem para esse formar e reformar da identidade docente.
O ensino colaborativo como possibilidade para a promoção de práticas pedagógicas em um contexto educacional inclusivo.
Authors: Souza Betina Weber de , König Franciele Rusch , Bridi Fabiane Romano de Souza
Published: September 2021

O presente texto configura-se como um relato de experiência, e emerge de ações pedagógicas pertinentes à educação inclusiva desenvolvidas na educação básica.  Tem como objetivo relatar experiências teórico-práticas de ensino colaborativo por meio do Programa Institucional de Bolsas de Iniciação à Docência-PIBID/Educação Especial, com ênfase nos anos finais do ensino fundamental. A experiência que fomenta o escrito derivou-se da colaboração de uma bolsista pibidiana, acadêmica de educação especial, com docentes de uma escola da rede pública de ensino, contemplando parceria no planejamento, desenvolvimento das propostas e avaliação, característica central do ensino colaborativo. Destaca-se a potência da proposta desenvolvida como alternativa para a qualificação das possibilidades de escolarização e aprendizagem de todos os estudantes, favorecendo a disponibilização de estratégias e recursos do Atendimento Educacional Especializado no contexto da sala de aula. Ainda, oferece subsídios teórico-práticos para a formação docente inicial, continuada, e em serviço, contribuindo para o desenvolvimento de práticas pedagógicas articuladas e pertinentes a um cenário educacional inclusivo.sivo.
Pensamiento tríadico y su relación con variables sociodemográficas de los estudiantes de Administración de Empresas
Authors: Lemus Quintero Jennifer Andrea
Published: September 2021

El objetivo de este documento es realizar análisis del pensamiento tríadico y su relación con variables sociodemográficas de los estudiantes de Administración de Empresas de la Universidad Francisco de Paula Santander Ocaña - UFPSO. La investigación partió de la aplicación de la prueba metodológica de Waldemar De Gregori e indagación de características sociodemográficas de la población estudiada. Los resultados conseguidos permitieron concluir que los estudiantes de Administración de Empresas de la UFPSO presentan una proporcionalidad en los tres tipos de mente a pesar de las diferentes condiciones sociales y demográficas en las que se encuentran. No obstante, también se pudo apreciar que, levemente, hay estudiantes bastante emocionales y buenos generando ideas, pero poco arriesgados en la ejecución de la acción.
Gestión e innovación para los artesanos de Cuetzalan Puebla
Authors: Gamboa Gochis Ana Luisa , Osorio Moranchel Helder
Published: September 2021

El Banco Internacional de Desarrollo en 2013 refirió tres aspectos, la creatividad, artes y cultura como materia prima; los derechos de propiedad intelectual, en particular con los derechos de autor, y; inserción directa en la cadena de valor. Es necesario fortalecer la identidad de los pueblos indígenas quienes aportan a la economía local, nacional e internacional en particular el estado de Puebla, México donde la actual gestión municipal 2018-2021 fomenta a la artesanía textil de bordado a mano, telar de cintura y fibra de jonote como producto de su creación.

Desde la coordinación de fomento al artesano generan interacción con ellos para fortalecer su actividad económica considerada como la tercera de importancia del lugar, la gestión y la innovación como variables de estudio serán analizados.

Es una investigación en curso, de tipo mixto por conveniencia donde se aplicó una prueba piloto a 40 artesanos para evaluar la influencia de la gestión en la innovación en el desarrollo del artesano para la elaboración de sus artesanías textiles en Cuetzalan Puebla, con los primeros resultados se identifica la edad, género, educación, tipo de organización y las primeras evidencias de las dimensiones donde se genera relación.
Implementation of a 3.5 kW resistive load bank for a single-cylinder diesel engine test bench
Authors: Duarte Forero Jorge Eliécer , Celis Quintero Miguel , Hernandez Acosta Gabriel
Published: September 2021

This article presents the implementation of a 3.5 kW resistive load bank applied to a four-stroke single-cylinder diesel engine test bench that operates with an alternator.   With this experimental test bench, it is possible to perform mechanical, thermodynamic, and polluting emissions studies in compression-ignited or induced internal combustion engines.   Applying the quantitative research methodology, the design of the electric charging system is carried out. Power control circuits and safety elements are designed for the load back. CAD software is used to design the structure and casing considering anthropometric measurements. Also, finite element analysis (FEA) is incorporated to verify the structural and thermal design criteria.   he implementation of an electrical and instrumentation acceleration system for sensing power and torque in low-displacement engines showed a measurement error of less than 1%. Similarly, the FEA allowed to quantify the maximum efforts and guarantee a safety factor above 5.   With the characterization of the implemented sensors, a correlation coefficient of up to 99.97% was achieved. The power measurement displayed an error lower than 3%, which leads to a high characterization capacity of any thermal machine with equal power or less than the designed one.
Analysis of the microstructural influence by laser cutting velocity
Authors: Rodríguez Baracaldo Rodolfo , López Camargo Mónica , Martin-Buitrago Aldemar
Published: September 2021

This research evaluates the influence of the CO2 laser cutting velocity in the heat-affected zone in a low- carbon steel. The control of laser cutting parameters is essential to ensure that the properties required in the material have not been affected, and avoid additional grinding processes on the cut surfaces. Morphologic, mechanic and microstructural tests were used to prove the influence of cutting process and its velocity on heat-affected zone. Transformation from ferritic into pearlitic structure and reduction in grain size were analyzed. Also, was evaluated a rise in hardness due to phase transformation. Better cutting conditions were evidenced in samples using a cutting velocity of 80 mm/s because the mean hardness obtained allow infer a good relation of properties and a smaller heat affected zone.
Experimental study of the characteristic curves of 0.5 HP radial pump with constant speed
Authors: Ibarra Bolaños Germán Alejandro , Arboleda Mena Jorge Mario , López Gustavo , Rojas Yohan
Published: September 2021

Radial (centrifugal) pumps are commonly used in industry and represent 22% of total consumption of the energy worldwide. The understanding of their operating conditions is important for a proper selection and use, specifically at the Best Efficient Point (BEP). This study analyzed the variation of the operating conditions of a common, small pump when the flow is regulated with a control valve at the pump discharge, keeping the rotational speed constant. The system consists in a closed loop using a turbine meter programmed in Arduino for flowrate measurement. The electric power and energy consumption were provided by an electronic Wattmeter, and the pressure at the suction/discharge of the pump was taken from Bourdon gauges. The minimum submergence of the pump intake was calculated with the Standard ANSI-HI-9.8 and the Bourdon gauges selection followed the recommendations of the Standard ASME B40.100-1998. All the measurements are part of the Energy equation for the pump-motor system (monoblock unit), whose H-Q curve is compared to manufacturer’s curve with reasonable agreement that served as validation. The electric power curve is the evidence that the flow regulation method is unappropriated because the power consumption increases as the flow is regulated. At the end, the efficiency curve of the motor-pump unit was presented, with a maximum value of 12%. The shock and recirculation losses are present, but the electrical losses are evidenced through excessive heating. The test bench will have a better pump and a variable frequency drive for further studies.
Diseño y manufactura de un dispositivo protector para codos, utilizando material polimérico flexible con alta resistencia mecánica, mediante la manufactura aditiva en 3D
Authors: Hernandez Reina Sara Alejandra , Casas Quintero Alvaro Nicolas , Aperador Chaparro Willian Arnulfo
Published: September 2021

En este artículo se presentan los resultados de la caracterización del material obtenido en impresión 3D compuesto por poliuretano termoplástico, en donde se seleccionó este material ya que fue el más adecuado para la fabricación de un dispositivo que absorba y disperse la energía. Adicionalmente, se adecuo a una chaqueta que con el propósito de usarlo en la disciplina de ciclismo. En el diseño se tuvo en cuenta diferentes tallas a medida del usuario y un proporcionado ajuste al codo, en donde se recibe la mayor energía de impacto. Se determinó la resiliencia del material polimérico a los que se les vario la estructura interna de relleno, dejando como variable fija la densidad de rellenado. El tipo de estructura interna del material con mayor energía almacenada antes de la deformación plástica fue el poliuretano termoplástico con rellenado cúbico, con el software ANSYS se determinó el comportamiento a comprensión y a tensión de la estructura
Fluorescent Probe for Simultaneous Detection of Human Serum Albumin and Sulfur Dioxide: A Theoretical Analysis
Authors: jia ang , huang he , zuo zhong-fu , liu xuezheng , Peng Yongjin
Published: September 2021

A small molecule probe for simultaneous detection of HSA and SO2 via
their distinct fluorescent signals was designed recently. This effective
tool provided a significant boost in understand underlying mechanism of
synergistic action between SO2 and HSA in disease. The structure and
fluorescent character of this probe molecule were studied under density
functional theory in this work. The different stable conformations of
probe C23 were found through theoretical method which explained the no
experimental fluorescent character of the probe itself. The electron
excitation analysis indicated the charge transfer process in the
restricted C23 (binding to the hydrophobic cavity of HSA) and CS (C23
reaction with SO2) when the molecules were under optical excitation. The
theoretical results could be helpful for understanding the electronical
properties in the probe and providing the insights for designing new
probe molecules.
The Exact Evaluation of Basic Two-Center Coulomb Integrals Appearing in Intermolecular Electrostatic Interaction Energy in Molecular Coordinate System
Authors: Çopuroğlu Ebru , Mamedov Bahtiyar
Published: September 2021

We proposed a general and effective approach for accurate calculating
method of the electron-electron, nuclear-electron and nuclear-nuclear
Coulomb electrostatic interaction energies. It is well known that
electron-electron, nuclear-electron and nuclear-nuclear Coulomb
electrostatic interaction energies reduced to basic two-center Coulomb
integrals. The analytical calculation of electrostatic interaction
energies with respect to basic two-center Coulomb integrals over Slater
type orbitals (STOs) in molecular coordinate systems allows us the
routine evaluation of molecular structures and related properties. In
this study we have introduced a new full analytical algorithm for
calculation of the basic two-center Coulomb integrals over STOs by using
Guseinov’s auxiliary functions especially interactions between
electrons. The auxiliary functions has been calculated by using the
exact recurrence relations which developed by Guseinov. The new approach
is successfully tested on earlier published studies data and can be
recommended for evaluation of related problems in atomic and molecular
physics.
Comparing Measurements of Intracardiac Echocardiography and Other Periprocedural Imaging of the Left Atrial Appendage For Percutaneous Occlusion
Authors: he changjian , Qian Liu , You Ling , Wang Lianxia , Yin Hongning , Li Ling , Song Denghao , Zhang Yan , Jing Weilin , Zheng huixin , zhang yuanyuan , Xie Rui
Published: September 2021

Background: Intracardiac echocardiography (ICE) has recently been used
as a safe and feasible imaging to guide left atrial appendage occlusion
(LAAO). However, there is no good comparison of the correlation of left
atrial appendage (LAA) measurements between ICE, transesophageal
echocardiography (TEE), cardiac computed tomography angiography (CCTA)
and fluoroscopy. Methods: We compared the correlation between ICE and
CCTA, TEE, fluoroscopy on two key LAA measurements of each patient: (1)
Lambre measured the landing zone and orifice; (2) Watchman measured the
ostium and depth. Results: In this study, the success rate of operation
was 100%, and no major adverse events occurred. For Lambre landing
zone, mean measurements were 22.5±4.0mm with ICE, 23.5 ±4.5mm CCTA,
22.0±4.5mm TEE, 21.5±4.4mm fluoroscopy (P < 0.001). R values
0.78 ICE/CCTA, 0.85 ICE/TEE, 0.81 ICE / fluoroscopy; For Lambre orifice,
mean measurements were 29.1±4.0mm with ICE, 31.0±3.9mm CCTA, 25.6±4.6mm
TEE and 28.9±3.9mm fluoroscopy (P < 0.001). R values 0.68
ICE/CCTA, 0.76 ICE/TEE, and 0.75 ICE/fluoroscopy. For Watchman ostium,
mean measurements were 22.7±3.2mm with ICE, 23.9±3.2mm CCTA, 21.9±3.1mm
TEE, and 21.6±3.0mm fluoroscopy (P<0.001). R values 0.69
ICE/CCTA, 0.85 ICE/TEE, and 0.71 ICE/fluoroscopy; For Watchman depth,
mean measurements were 22.1±3.1mm with ICE, 24.8±4.1mm CCTA, 23.7±2.9mm
TEE, and 21.1±3.3mm fluoroscopy (P=0.002). R values 0.31 ICE/CCTA, 0.67
ICE/TEE, and 0.41 ICE/fluoroscopy. Conclusion: ICE from LA can be a safe
and efficacious imaging option to guide LAAO, and ICE has good
correlation with CCTA, TEE and fluoroscopy.
TWISTED DWARF1 regulates Arabidopsis stamen development by differential activation of ABCB-mediated auxin transport
Authors: Liu Jie , Ghelli Roberta , Cardarelli Maura , Geisler Markus
Published: September 2021

Despite clear evidence that a local accumulation of auxin is likewise
critical for floral organ initiation than for vegetative tissues, much
less is known about the molecular key players that regulate
auxin-controlled flower development. Here, by an analysis of
physiological and morphological parameters and by a spatial and temporal
dissection of auxin fluxes and expression of key players of
ABCB-mediated auxin transport in the Arabidopsis flower, we demonstrate
a crucial role for the FKBP42, TWISTED DWARF1 (TWD1), in the regulation
of flower development. Our analyses revealed that TWD1 promotes flower
shape and number, stamen elongation, pollen maturation, nectary
functionality and seed development. Most of the described developmental
defects in twd1 are shared with the abcb1 abcb19 mutant, which can be
attributed to the fact that TWD1 as a described ABCB chaperon is a
positive regulator of ABCB1 and ABCB19-mediated auxin transport. We
predict an overall housekeeping function for ABCB1 during earlier
stages, while ABCB19 seems to be responsible for the key event of rapid
elongation at later stages of stamen development. Our data indicate that
TWD1 controls flower development by differential activation of
ABCB-mediated auxin transport.
“Extra!” Using the Newsvendor Model to Optimize War Reserve Storage
Authors: Pak Minou , Peeples Joshua , Klamo Joseph
Published: September 2021

The United States Marine Corps (USMC) Installation and Logistics Command requested a study for determining appropriate inventory levels of war reserve materiel to meet future operational needs under surge demands in uncertain environments. This study sought to explore a potential approach by using the common newsvendor model, but modified for a military scenario. The authors’ novel version of this core concept considers the purchase and storage costs of an item and proposes an intangible cost function to capture the consequences of a shortage. Further, they show a sample application of the model using a ubiquitous military item—the BA-5590/U battery. The output of the model provides USMC with a new tool to optimize inventory levels of a given item of interest, depending on scenario inputs.
Aligning Program Management Competencies to Industry Standards
Authors: Karnes Jonathan , Mortlock Robert
Published: September 2021

The 2020 National Defense Authorization Act mandated that acquisition career fields realign their certification requirements to be based on the nationally recognized standards of an accredited third party. This study offers recommendations for improving the DoD program management (PM) training standards by providing traceability between the DoD PM competencies and the Project Management Institute (PMI)’s standards for project, program, and portfolio management. The study elaborates on the extent of alignment, finding that 96% of the DoD PM competency elements align to PMI standards. Areas of misalignment identify opportunities to augment DoD PM training and highlight areas where DoD PM training deviates from industry standards.
"Extra!" Using the Newsvendor Model to Optimize War Reserve Storage
Authors: Pak MAJ Minou , Peeples MAJ Joshua L. , Klamo Joseph T.
Published: September 2021

The United States Marine Corps (USMC) Installation and Logistics Command requested a study for determining appropriate inventory levels of war reserve materiel to meet future operational needs under surge demands in uncertain environments. This study sought to explore a potential approach by using the common newsvendor model, but modified for a military scenario. The authors’ novel version of this core concept considers the purchase and storage costs of an item and proposes an intangible cost function to capture the consequences of a shortage. Further, they show a sample application of the model using a ubiquitous military item—the BA-5590/U battery. The output of the model provides USMC with a new tool to optimize inventory levels of a given item of interest, depending on scenario inputs.
Strength of eccentrically tensioned reinforced concrete structures with small eccentricities by normal sections
Authors: Dmytrenko Yevhen , Yakovenko Ihor , Fesenko Oleg
Published: September 2021

It is implemented the method of normal rectangular sections slab (shell) reinforced concrete elements strength calculating with flat eccentric tensile strength using the deformation m ethod. The results of the calculation are analyzed for the case of eccentric tension with small eccentricities with varying next parameters: the height of the cross section and the reinforcement coefficient. It is investigated the character of diagrams condition change of section “N – ?c(1)” at gradual change of the stress-strain state from eccentric to the central tension. It is revealed that when the eccentricity of external forces decreases, the compressed zone of concrete decreases until its complete disappearance, and at rather small values of eccentricities of force application the balance between external and internal forces cannot be found by the method of current norms. An equilibrium is found between internal and external forces only at a two-digit diagram of the distribution of relative longitudinal deformations (in the case of a compressed zone). Variants of the given problem decision without considerable loss of calculations accuracy are offered, the most expedient of which is transition to algorithm of calculation by a method of limiting efforts. It was accepted as the basic in the previous building norms. The results of numerical calculations performed in the software complex “Lira-CAD” and the corresponding mathematical modeling confirmed the rationality and allowable accuracy of further calculations by this method.
Operation and maintenance financial feasibility analysis of centralized domestic wastewater treatment system (case study: Palembang City Sewerage Project)
Authors: Estu Larap K. , Susanti Betty , Hadinata Febrian
Published: September 2021

Budget needed for operation and maintenance of centralized domestic wastewater management in Indonesia is often overlooked. This results in fail systems, high idle capacity, and abandoned assets. While the economic feasibility often used as the basis for centralized domestic wastewater infrastructure construction, the financial feasibility often shown a different result. The construction phase will be feasible according the analysis, while the operation and maintenance phase will have a different result. As unsolicited projects, the operation and maintenance of sewerage in Indonesia always have budget difficulties, thus needed scenario to resolve the matter. In this study, cost and revenue variable will be analyzed to determine the feasibility value based on NPV, BCR, and IRR calculations. The revenue comes from user charge tariffs on household and commercials connections, and cost variable consists of: chemical usage cost; sludge disposal cost; personnel wage cost; fuel and electricity cost; spare-part replacement cost. The analysis will determine whether both household connection and commercials connection in the sewerage system have positive results. Should negative results emerged, follow up analysis added to elevate the results consists of following scenarios: sensitivity analysis for tariffs adjustment; sensitivity analysis adding grant as option; sensitivity analysis adding loan as option. While analysis of base tariffs shown negative results on NPV, BCR, and IRR calculation, the follow up analysis shown significant changes thus the results is desirable.
Removal of Meropenem by using Lemna minor
Authors: Saad Noora , Al-Dulaimi Samara
Published: September 2021

In this paper we presented a case study about the removal of a pharmaceutical contamination (in this case Meropenem) from the environment using organic natural substance (in this case study is Lemna minor). The study proved the efficiency of the used material to remove the contamination of three specific contamination levels of Meropenem. The experimental testing proved the concept, the effect on two vital measures (the chemical oxygen demand – COD, and the root length), which showed improvement in both measures. The degradation mechanism was proven to be not arbitrary by testing the degradation behavior measured practically to four kinetic models. The practical work was found to fit perfectly with the Grau second order model as the simulation work included in the paper shows. Based on this study it can be proven that the dangerous chemicals resulted from the residue of a pharmaceutical substances can be removed efficiently using a totally natural environmental friendly material.
A new chain of inequalities involving the Toader-Qi, logarithmic and exponential means
Authors: Yang Zhen-Hang , Tian Jing-Feng
Published: September 2021

In this paper, we establish an interesting chain of sharp inequalities involving Toader-Qi mean, exponential mean, logarithmic mean, arithmetic mean and geometric mean. This greatly improves some existing results.
Commutative von Neumann regular rings are 1-Gröbner
Authors: Petrovic Zoran , Roslavcev Maja
Published: September 2021

Let R be a commutative von Neumann regular ring. We show that every finitely
generated ideal I in the ring of polynomials R[X] has a strong Gr?bner
basis. We prove this result using only the defining property of a von
Neumann regular ring.
Anterior Skull Base Tumors and Surgery
Authors: Fastenberg Judd H. , Nyquist Gurston G. , Barton Blair M.
Published: September 2021

Anterior skull base surgery requires intimate knowledge of a highly complex anatomic region containing critical neurovascular structures. A wide array of pathologies can occur along the anterior cranial base, including meningiomas, esthesioneuroblastomas, pituitary adenomas, craniopharyngiomas, chondrosarcomas, and chordomas. Advancements in endoscopic sinus surgery have allowed many of these tumors to be effectively treated via an endoscopic endonasal technique. This approach obviates the need for large incisions causing cosmetic deformity, improves magnification of the surgical field, and offers a direct path to lesions thus avoiding retraction of structures such as the brain and nerves. Surgeons must understand the limitations of endoscopic techniques and consider open or combined open and endoscopic approaches when appropriate. Reconstructive anterior skull base techniques vary depending on the size and location of defects, along with factors such as intracranial pressure and patient co-morbidities. Large skull base defects require multilayer reconstruction that include a watertight primary dural repair with either synthetic or autologous tissue, followed by local vascularized tissue flaps.

This review contains 8 figures, 2 videos, 4 tables and 33 references
Key words: Anterior skull base, meningioma, esthesioneuroblastoma, chordoma, pituitary, CSF leak, nasosptal flap, dural repair, expanded endonasal approaches, endoscopic surgery
Kidney Outcomes Associated With SGLT2 Inhibitors Versus Other Glucose-Lowering Drugs in Real-world Clinical Practice: The Japan Chronic Kidney Disease Database
Authors: Nagasu Hajime , Yano Yuichiro , Kanegae Hiroshi , Heerspink Hiddo J.L. , Nangaku Masaomi , Hirakawa Yosuke , Sugawara Yuka , Nakagawa Naoki , Tani Yuji , Wada Jun , Sugiyama Hitoshi , Tsuruya Kazuhiko , Nakano Toshiaki , Maruyama Shoichi , Wada Takashi , Yamagata Kunihiro , Narita Ichiei , Tamura Kouichi , Yanagita Motoko , Terada Yoshio , Shigematsu Takashi , Sofue Tadashi , Ito Takafumi , Okada Hirokazu , Nakashima Naoki , Kataoka Hiromi , Ohe Kazuhiko , Okada Mihoko , Itano Seiji , Nishiyama Akira , Kanda Eiichiro , Ueki Kohjiro , Kashihara Naoki
Published: September 2021

Objective: Randomized
controlled trials have shown kidney protective effects of sodium glucose
transporter 2 (SGLT2) inhibitors, and clinical practice databases have
suggested that these effects translate to clinical practice. However, long-term
efficacy as well as whether the presence or absence of proteinuria and the rate
of estimated glomerular filtration rates (eGFR) decline prior to SGLT2
inhibitors initiation modifies treatment efficacy among type 2 diabetes
mellitus (T2DM) and chronic kidney disease (CKD) patients is unknown.

Research Design and Methods: Using the Japan Chronic Kidney Disease Database (J-CKD-DB), a
nationwide multicenter CKD registry, we developed propensity scores for SGLT2
inhibitor initiation, with 1:1 matching with patients who were initiated on
other glucose-lowering drugs. The primary outcome included rate of eGFR
decline, and the secondary outcomes included a composite outcome of 50% eGFR
decline or end-stage kidney disease.

Results: At
baseline, mean age at initiation of the SGLT2 inhibitor (n=1,033) or other
glucose-lowering drug (n=1,033) was 64.4 years; mean eGFR was 68.1 mL/min per
1.73 m²; and proteinuria was apparent in 578 (28.0%) of included patients.
During follow-up, SGLT2 inhibitor initiation was associated with reduced eGFR
decline (difference in slope for SGLT2 inhibitors vs other drugs 0.75
mL/min/1.73 m² per year (0.51 to 1.00). During a mean follow-up of 24 months, 103
composite kidney outcomes occurred: 30 (14 events
per 1,000 patient-years) among the SGLT2 inhibitors group and 73 (36 events per
1,000 patient-years) among the other drugs group (hazard ratio 0.40, 95% CI 0.26
to 0.61). The benefit provided by SGLT2 inhibitors was consistent irrespective
of proteinuria and rate of eGFR decline before initiating SGLT2 inhibitors (pheterogeneity
≥0.35).

Conclusions: The benefits of SGLT2 inhibitors on kidney function
as observed in clinical trials translate to patients treated in clinical
practice with no evidence that the effects are modified by the underlying rate
of kidney function decline or the presence of proteinuria.
Modelo de enseñanza para adopción de tecnología de automatización en sistemas irrigados para pequeños agricultores
Authors: Tangarife-Escobar Hector , Pedraza-Tunjo Sebastián , Cárdenas-Miranda Camila
Published: September 2021

El presente estudio pretende mostrar un modelo de adopción tecnológica intuitiva para el manejo operativo de sistemas irrigados autónomos, dirigido a agricultores. En general, con la migración de personas del campo a la ciudad, se presenta una disminución significativa de la mano de obra, circunstancias que demandan mejorar los rendimientos de los procesos, sin embargo, una de las principales problemáticas está relacionada con la baja adopción de tecnología, dada por la oposición que ejerce el agricultor al cambio, esto es, respecto a las formas convencionales de realizar las actividades agrícolas. Es así como esta iniciativa pretende optimizar el trabajo agrícola al incentivar al agricultor en la apropiación y el uso de la tecnología. El estudio se desarrolló por parte del Centro de Biotecnología Agropecuaria (CBA) del SENA. Se realizó una revisión del estado del arte para evaluar de manera detallada los antecedentes asociados con la apropiación de la tecnología en el área agropecuaria. Posteriormente, se diseñó una interfaz gráfica sobre una pantalla táctil que se controla mediante la programación de un controlador lógico programable (PLC) y, finalmente, se llevaron a cabo pruebas de funcionamiento en campo con posibles agricultores que desconocen las nuevas tecnologías para la agricultura. A partir del estudio, se obtuvo que el modelo facilita la forma de aprendizaje y entendimiento de la tecnología de los sistemas irrigados. En un 89 % de aceptación los agricultores reconocen que los sistemas de irrigación automáticos facilitan las tareas y disminuyen los tiempos sobre el cultivo, promoviendo de manera progresiva la confianza del agricultor de base en los sistemas de riego con diferentes grados de autonomía. El modelo de enseñanza facilita los primeros pasos en el uso de tecnología y apropiación de esta, lo que demuestra ser un aporte significativo en las labores agrícolas.
El efecto de la covid-19 en la impartición de cursos de matemáticas: evidencia experimental en una macrouniversidad de México
Authors: Alvarado Lagunas Elías , Morales Ramírez Dionicio , Ortiz Rodríguez Jeyle
Published: September 2021

Este artículo se centra en analizar los efectos que ha generado la pandemia por la covid-19 en la impartición de los cursos de matemáticas en la Universidad Autónoma de Nuevo León (UANL), máxima casa de estudios del norte de México. Para tal fin, se aplicó una encuesta en línea a 748 educandos de licenciatura en el segundo trimestre del año 2020. Con la información recabada se empleó un modelo Tobit censurado por la derecha, el cual permitió cuantificar el rendimiento académico de los estudiantes antes y durante el confinamiento en sus cursos o asignaturas de matemáticas en esta macrouniversidad. Entre los principales resultados se encuentra que la aplicación de software y plataformas digitales en la impartición de los cursos de matemáticas durante la contingencia sanitaria incrementa la eficiencia de los educandos en la solución y culminación de los ejercicios y los laboratorios, encargados por los docentes, en 23.2 %, mientras que el tiempo promedio para llevarlos a cabo es de 25.4 y 50.8 minutos, respectivamente.
Course review horay and critical thinking skills: the effective teaching model for students’ grammar competence in remote EFL classrooms
Authors: Zuhriyah Mukminatus , Fajarina Maskhurin
Published: September 2021

Since the COVID-19 pandemic, EFL lecturers need to be creative in handling their remote teaching. However, scarce studies investigated the use of course review horay (CRH) and students’ critical thinking skills (CTS) in remote EFL classrooms especially in grammar classes. The study aimed to explore whether or not CRH was more effective than explanation model to teach grammar and the students having high CTS had better grammar competence than those of low CTS. This experimental study employed a 2x2 factorial design. The population was the second semester students of non-English departments in a private university in East Java, Indonesia. The sample was four groups comprising of two groups (high and low CTS) in the experimental class and two groups (high and low CTS) in the control class. To categorize them into high and low CTS, an Indonesian argumentative essay writing test was used. After six meetings of treatment, the students did the grammar test. The grammar scores were, then, analyzed using ANOVA and TUKEY tests. The results indicated that CRH was more effective and the students with high CTS possessed better grammar competence. The present study implies that CRH and CTS created a joyful learning atmosphere in remote grammar teaching.
EFL teacher educators’ experiences in teaching critical reading: evidence from Indonesia
Authors: Yunus Muhammad , Ubaidillah M. Faruq
Published: September 2021

While extensive studies have explored issues of teaching critical reading in English as a foreign language (EFL) classes, there is a paucity of research that examines teacher educators’ conceptions of teaching critical reading in the EFL contexts. To fill the gap, this phenomenological study probes into EFL teacher educators’ experiences in teaching critical reading. It specifically looks at teacher educators’ conceptions of teaching critical reading and how their teaching practices contribute to the development of students’ critical reading skills. Data were generated through in-depth interviews with nine teacher educators in a private university in Malang, Indonesia. Findings suggest that the teacher educators’ conceptions of teaching critical reading, as geared by their lived experiences, involve basic conceptions of teaching critical reading, teaching critical reading from a philosophical lens, and critical thinking empowerment in reading classes. The study also documents that teaching critical reading encompasses higher order thinking skills enacted in the process of reading. Practically, the study’s findings call for the enactment of pedagogic trainings for teacher educators in order to construe their basic tenets of teaching critical reading, the philosophies behind such a teaching practice, and the empowered learning activities in the reading classes.
Changes to intraocular pressure and systemic blood pressure in dogs during moderate treadmill exercise - a short communication
Authors:   Department of Experimental and Clinical Medicine, University of Catanzaro, Italy, Ragusa Monica , Pugliese Michela , Alibrandi Angela , Niutta Pietro P. , De Majo Massimo , La Maestra Rocky , Passantino Annamaria
Published: September 2021

Physical exercise in humans induces changes in intraocular pressure, relating to the type and intensity of the workload. The purpose of the present study was to evaluate the variations in intraocular pressure and arterial blood pressure in dogs that underwent physical exercise on a treadmill. Thirty dogs were submitted to physical exercise consisting of walking (15 minutes), trotting (20 minutes), and walking (10 minutes). The intraocular pressure, blood pressure and pulse rate were recorded for each dog before starting the treadmill exercise, immediately after it ended, and after 20 minutes of passive recovery. Two-way repeated analysis of variance measurement showed the significant effect of treadmill exercise (P≤0.01) on intraocular pressure, pulse rate and diastolic blood pressure. No significant changes were observed to systolic blood pressure. Intraocular pressure and diastolic blood pressure decreased significantly during the passive recovery, and were strongly related. The pulse rate was significantly lower during the passive recovery. Although the mechanism determining the reduction in intraocular pressure during exercise remains not fully understood, our results suggest that it is strongly related to variations in arterial blood pressure.
The effect of complex herbal extract and methotrexate on suppressing adjuvant arthritis in rats
Authors:   Department of Biomodels, State Research Institute Centre for Innovative Medicine, Vilnius, Lithuania, Bradūnaitė Rūta , Leonavičienė Laima , Akramas Laimis , Vasiliauskas Audrius , Dumalakienė Irena , Vilienė Rita , Jonauskienė Irena , Mackiewicz Zygmunt , Leonavičiūtė - Klimantavičienė Miglė
Published: September 2021

The present study evaluated the therapeutic benefits of complex herbal preparation named CBMDS, consisting of turmeric (Curcuma longa), Boswellia (Boswellia serrata), Methylsulphonylmethane, Devil’s Claw (Harpagophytum procumbens) and Silymarin, using it in combination with methotrexate, in order to suppress adjuvant arthritis in rats, and to attenuate methotrexate-induced liver damage. Adjuvant arthritis was induced in 28 rats by a single subplantar injection of complete Freund’s adjuvant (0.1 mL) into the left hind paw. The animals were divided into four groups (with seven animals in each). Group I received CBMDS, Group II - CBMDS in combination with methotrexate, and Group III just methotrexate. The treatment lasted from day 0 to day 17 (CBMDS was given daily except weekends in a dose of 160 mg/kg, methotrexate - 2 mg/kg once a week). Group IV was the control group. Clinical (body weight, hind paw volume, erythrocyte sedimentation rate, leukocyte count), biochemical (serum pro-/antioxidant activity markers), immunological (serum interleukin levels) and histological changes in joint and liver tissues were evaluated. CBMDS significantly alleviated arthritis and reduced hepatic damage, which was more evident in the methotrexate group. The combined treatment also markedly reduced arthritic symptoms and levels of malondialdehyde. Antioxidant activity was significantly higher in treated Groups I and II. CBMDS and its combination with methotrexate promoted anti-arthritic action, reduced histological changes in the joint tissues, and minimized methotrexate-induced liver toxicity.
Pathomorphological evaluation of hepatobiliary lesions in dogs and cats of Ankara region
Authors:   Department of Pathology, Faculty of Veterinary Medicine, Ankara University, Ankara, Turkey, Abou Monsef Yanad , Kutsal Osman
Published: September 2021

The objective of this study was to investigate pathological disorders of the hepatobiliary system in dogs and cats in Ankara using pathomorphological methods, and to determine the types and frequency of the observed lesions. Furthermore, we aimed to evaluate hepatic reparation as a reaction of the liver to injury with different hepatobiliary lesions using immunohistochemical methods. Livers obtained from 56 cats and 74 dogs submitted for post-mortem investigation were examined macroscopically and microscopically. Samples with hepatic fibrosis were stained immunohistochemically with an α-SMA antibody. Lesions were found in 98% of the livers of the examined dogs and cats. The most common histopathological diagnoses were hepatitis (39.28%), hepatocellular lipidosis (16.07%), and cholangitis/cholangiohepatitis (14.28%) in cats. In dogs they were hepatitis (28.38%), passive congestion (25.68%) and proliferative lesions (21.62%). For some hepatobiliary lesions, breed, age and gender predispositions were observed. Immunohistochemically, the α-SMA antibody positively stained parenchymal, portal and septal myofibroblasts. A positive correlation was verified between immunohistochemical α-SMA scores and histochemical fibrosis scores. This is the first study in Turkey documenting both the incidence of hepatobiliary lesions among feline and canine species, and their pathomorphological features. In terms of reparation, the major role of the hepatic myofibroblasts in liver fibrosis was observed. There were variations in the intensity and location of positively stained cells according to the type of lesion. The conclusion of this research indicates the need to pay attention to certain hepatic lesions in dogs and cats, and provides a reference standard for further clinical and histopathological studies.
Effects of a radio frequency electromagnetic field on honey bee larvae (Apis mellifera) differ in relation to the experimental study design
Authors:   Department of Physiology and Radiobiology, Faculty of Veterinary Medicine, University of Zagreb, Zagreb, Croatia, Vilić Marinko , Žura Žaja Ivona , Tkalec Mirta , Štambuk Anamaria , Šrut Maja , Klobučar Goran , Malarić Krešimir , Tucak Perica , Pašić Selim , Tlak Gajger Ivana
Published: September 2021

Exposure to radiofrequency electromagnetic fields (RF-EMF) at the operating frequencies of different communication devices can cause various biological effects. However, there is a lack of studies on the oxidative stress response and genotoxicity in the honey bee (Apis mellifera) after exposure to RF-EMF. In this study, we investigated the oxidative stress and DNA damage in honey bee larvae situated in waxcomb cells, exposed to modulated RF-EMF 23 Vm-1. The glutathione S-transferase activity decreased, whereas the catalase activity increased significantly in the honey bee larvae upon RF-EMF exposure. Superoxide dismutase activity, the level of lipid peroxidation, and DNA damage were not statistically altered in exposed honey bee larvae when compared to the control group. These results suggest that the biological effects of modulated RF-EMF in honey bee larvae depend on the exposure design.
如何看待政府在疫病中的干預？自由至上主義的道德困境
Authors: ZHANG Ellen Y.
Published: September 2021

LANGUAGE NOTE | Document text in Chinese; abstract also in English.

在「自由至上主義」(Libertarianism)的政治哲學詞典中，「政府干預」(state interference)或「政府父權主義」(state paternalism)基本上是一個貶義詞，因為政府意味著官僚、腐敗、無效率，意味著對公民個體自由的干預和限制。然而，自2020年以來在全球範圍內爆發和流行的新冠疫情，讓一貫反政府干預、堅持「小政府」原則的自由至上派的學者倍受挑戰。 面對疫情的肆虐，許多人認為政府的干預（如封城、鎖國、宵禁、隔離、邊控等措施的實行）是必要的。本文探討自由至上主義的自由觀在疫病中所面臨的道德兩難以及政府應在公共衛生管理中扮演的角色。作者指出，雖然自由至上主義的一些有關自由的理念在現實生活中顯得過於教條和不切實際，但從另一個角度看，當我們一再倒向政府的力量以抗擊疫情之時， 我們更需要自由至上主義對我們的提醒，以防政府利用疫情不斷擴大自身的權力範圍，最終傷害每個人的自由權利。

For Libertarians, state interference or state paternalism has a pejorative meaning given that government often implies bureaucracy, corruption, and inefficiency. However, such a view has faced significant resistance since the outbreak of the Covid-19 pandemic. For the sake of public health, many people now believe that we must accept much greater governmental intervention in our lives and that it is morally permissible and necessary to have public policies such as lockdowns, mandatory social distancing, border restrictions, and mandatory vaccination. Is it true that “there are no libertarians in a pandemic”? This paper explores the role of the government and the meaning of individual liberty in the face of the current public health crisis. The author contends that the Libertarian views of civil liberty and self-ownership should be taken more seriously as the government obtains more power and a host of extraordinary interventions are being implemented during the pandemic.
The use of distance learning technologies in a pedagogical university: a comparative analysis of students’ attitude in 2020-2021
Authors: Basov Igor Ivanovich , Karapkova Olesya Grigorievna , Khlopkova Viktoria Mikhailovna , Shnaider Vladimir Gennadievich
Published: September 2021

The article provides the analysis of modern trends in the development of higher pedagogical education and the influence of digitalization on the educational process in a pedagogical university. The issue of the formation of information and communication competencies of students and teaching staff in the context of digitalization is considered as well as the attitude of students towards distance and blended forms of study. The experience of implementing distance and blended learning at the Faculty of History of the Armavir State Pedagogical University in is analyzed basing on surveys carried out in 2020-2021.The results shown here serve to show us the importance and place of distance education, post-pandemic.
Prerequisites for self-determination and the sovereignty of Tuva (Russia) in 1921
Authors: Baksheev Andrey Ivanovich , Novikov Pavel Alexandrovich , Mongush Alla Lospanovna , Saaya Saida Vladimirovna , Shepeleva Julia Sergeevna , Rakhinsky Dmitry Vladimirovich
Published: September 2021

The article analyzes the prerequisites of self-determination and sovereignty of Tuva in 1921. Briefly, the general context of events is revealed, the main episodes and key personalities are listed. Using historical-genetic, comparative-historical and problem-chronological methods, the positions of Mongolia and Soviet Russia and their relationship on the status of Tuva, the organization and convocation of the All-Tuva Constituent Khural, which proclaimed the independence of Tuva, as well as the consequences of the declaration of independence of Tuva, were reconstructed. The role of the authorized representative of the Sibrevkom in Uryanhai I.G. Safyanov in this process is shown. In conclusion, the authors conclude that the emergence of a sovereign Tuva state was made possible both due to the contradictory political situation in Asia and due to the role of I.G. Safyanov in history. Since 1921, Tuva began to live and develop in the political and economic conditions created by the Constituent Khural.
Research of the system of formation of professional competence of future managers of physical culture
Authors: Prystupa Yevhen , Kryshtanovych Svitlana , Pasko Olha , Prudka Liudmyla , Matiienko Tetyana
Published: September 2021

The main purpose of the study is to analyze the effectiveness of the system of formation of professional competence of future managers of physical culture and sports. Recently, much attention has been paid to reforming the education system in the country. The existing system of training qualified personnel for the sphere of physical culture and sports does not correspond to the modern needs of society. In this regard, the training of sports managers and the formation of their professional competence is of particular importance. The actual aspects of the definition and diagnosis of professional competence are confirmed by a number of international educational research programs, proactive scientific developments on this topic. The result of the study is to determine the main aspects of the effectiveness of the system of forming the professional competence of future managers of physical culture and sports.
Alkol Tüketiminin Osmanlı Kamusal Hayatında Yarattığı Sorunlar: İkinci Meşrutiyet Dönemi ve Sonrasından Örnekler
Authors: ARSLAN Fatih
Published: September 2021

Kullanıldığında insanlara bir süreliğine sarhoşluk hali veren alkol, tarihsel süreç içerisinde pek çok medeniyet tarafından bilinmiş ve tüketilmiştir. Bilinçsiz ve kontrol dışı kullanıldığında çeşitli problemlere neden olan alkol, Osmanlı Devleti sınırları içerisinde de bazı sosyo-ekonomik sıkıntılara sebebiyet vermiştir. Bu sıkıntılar kamusal hayata da sirayet etmiş ve devletin çeşitli kurumlarında görev yapan memurlar içki yüzünden bazı asayiş ihlallerine neden olmuştur. Devletin okulundaki öğrenciden ordusundaki askere, karakolundaki polisten bahriyesindeki nefere kadar pek çok kamu çalışanı alkolün tesiriyle olaylara karışmış ve işledikleri suçlardan ötürü cezalandırılmıştır. Bu makalede birtakım örneklerle, Osmanlı devletinde görev yapan memurların, aldıkları alkolün etkisiyle birlikte çıkardığı asayiş olayları anlatılarak bunun sonucunda karşılaştıkları sorunlar ile çektikleri cezalara değinilmiştir.