bluuebunny/crossref_metadata_2025 huggingface dataset:
PREFERENSI KARYAWAN TERHADAP RUANG BEKERJA DI RUMAH TINGGAL SELAMA MASA PANDEMI BERDASARKAN KEPRIBADIAN MYERS-BRIGGS TYPE INDICATOR (MBTI)
Authors: Mudzakir Yogi , Nimpuno Wibisono Bagus
Published: February 2022

Work from home (WFH) merupakan kegiatan bekerja yang dilakukan dari rumah, kegiatan tersebut bukan merupakan hal baru pada masa revolusi industri 4.0 dan sudah dilakukan sejak tahun 1980an, saat internet telah ditemukan. Namun, kegiatan tersebut massif dilakukan pada saat pandemik covid-19 yang merebak pada tahun 2020 diseluruh dunia. Di Indonesia, kegiatan WFH dilakukan oleh beberapa perusahaan merujuk pada peraturan pemerintah terhadap pengendalian penularan virus. Karyawan dituntut untuk beradaptasi dengan lingkungan bekerja yang baru, yaitu rumah tinggal. Bekerja dari rumah berpotensi menimbulkan gangguan terhadap kesehatan mental, diantara stress hingga depresi, sehingga untuk mengurangi dampak yang ditimbulkan akibat aktifitas bekerja dari rumah, diperlukan sebuah pendekatan dalam perancangan rumah tinggal untuk memenuhi kebutuhan aktifitas bekerja di rumah. Perancangan tersebut disusun berdasarkan pendekatan kepribadian Myers-Briggs Type Indicator (MBTI) karena setiap individu memiliki keunikan karakter yang berpengaruh terhadap efisiensi, efektifitas kerja dan kesehatan mental. Data diperoleh dari kuesioner terbuka dengan pendekatan visual/gambar. Hasil akhir yang diperoleh dari penelitian ini adalah pola layout ruang bekerja yang diinginkan berdasarkan kepribadian MBTI dari hasil analisis isi. Work from home (WFH) is a work activity that is carried out from home, this activity has been carried out for a long time since the industrial revolution 4.0 began, specifically in the 1980s, when the internet was invented. However, this activity was carried out massively at the time of the Covid-19 pandemic that broke out in 2020 around the world. In Indonesia, WFH activities are carried out by several companies referring to government regulations on controlling virus transmission. Employees are required to adapt to a new work environment, namely a home. Working from home has the potential to cause mental health problems, ranging from stress to depression, so to reduce the impact of working from home, an approach is needed in residential design to meet the needs of working at home activities. The design is based on the Myers-Briggs Type Indicator (MBTI) personality approach because each individual has a unique character that affects work efficiency, effectiveness and mental health. Data obtained from open questionnaires with a visual / image approach. The final result obtained from this research is the desired workspace layout pattern based on the MBTI personality from the results of the content analysis.
An insight in recurrent colon cancer: determining its risk factors and mechanisms to better assess and prevent this complication based on a case report
Authors: Mseddi Mohamed Ali
Published: February 2022

The goal of the surgery is to eradicate the cancerous process without
compromising patient’s autonomy. Not leaving a residual tumour-spot that
will offer a niche for local tumour recurrence is the surgeon’s
obsession. We highlight the mechanisms and risk factors to elaborate
preventive and therapeutic means to combat this complication.
Reducing Inequality in the People’s Republic of China through Tax and Fiscal Reforms
Authors: Peschel Dominik
Published: February 2022

Taking into account recent changes to the tax system and fiscal relations, the paper offers policy recommendations to reduce inequality by strengthening redistribution mechanisms.
Salt stress tolerance potential of selected rice cultivars of Pakistan
Authors: Tawab Faiza , Ahmad Afaq , Nasim Adnan , Tawab Saleha , Munir Iqbal
Published: February 2022

Ten local rice varieties (Sarshar, Pakhal, Sada Hayat, Jajai-77, NIR-9,
RI-DR-92, JP-5, Shaheen Basmati, Shadab-31 and TN-1) were evaluated for
salinity stress (0, 50, 75 and 100 mM of NaCl) tolerance at seedling stage,
in Completely Randomized Design (CRD). On an average the root length, shoot
length and the relative growth rate of all rice varieties decreased linearly
with increased levels of salinity. Based on the individual results of all
the parameters studied, Pakhal was found to be the most salt tolerant
variety. The germination rate of the varieties RI-DR-92 and TN-1 was better
at higher levels of salinity (75 and 100 mM NaCl) among all the tested
varieties. While, considerable reduction in germination rate was recorded
for Jajai-77. The varieties RI-DR-92 and TN-1 that were more affected
showing more reduction in shoot length (4.2 cm and 4.4 cm), root length (2.9
and 3.2 cm) and relative growth rate (0.22 and 0.14 g/gday), grown at 75 and
100 mM NaCl respectively. The variety Pakhal showed less reduction in shoot
length (1.5 and 2.7 cm), root length (0.95 and 1.0 cm) and relative growth
rate (0.073 and 0.075 g/gday), grown at 75 and 100 mM NaCl, respectively as
compared to control. However, according to Stress Susceptibility Index
(SSI), TN-1 was observed to be the most tolerant and Jajai-77 was the most
susceptible variety to salt stress. The most tolerant rice varieties
differentiated in the current study could be used to produce higher yields
under saline conditions.
Neighborhood Socioeconomic Environment and Risk of Type 2 Diabetes: Associations and Mediation Through Food Environment Pathways in Three Independent Study Samples
Authors: Thorpe Lorna E. , Adhikari Samrachana , Lopez Priscilla , Kanchi Rania , McClure Leslie A. , Hirsch Annemarie G. , Howell Carrie R. , Zhu Aowen , Alemi Farrokh , Rummo Pasquale , Ogburn Elizabeth L. , Algur Yasemin , Nordberg Cara M. , Poulsen Melissa N. , Long Leann , Carson April P. , DeSilva Shanika A. , Meeker Melissa , Schwartz Brian S. , Lee David C. , Siegel Karen R. , Imperatore Giuseppina , Elbel Brian
Published: February 2022

OBJECTIVE

We examined whether relative availability of fast-food restaurants and supermarkets mediates the association between worse neighborhood socioeconomic conditions and risk of developing type 2 diabetes (T2D).

RESEARCH DESIGN AND METHODS

As part of the Diabetes Location, Environmental Attributes, and Disparities Network, three academic institutions used harmonized environmental data sources and analytic methods in three distinct study samples: 1) the Veterans Administration Diabetes Risk (VADR) cohort, a national administrative cohort of 4.1 million diabetes-free veterans developed using electronic health records (EHRs); 2) Reasons for Geographic and Racial Differences in Stroke (REGARDS), a longitudinal, epidemiologic cohort with Stroke Belt region oversampling (N = 11,208); and 3) Geisinger/Johns Hopkins University (G/JHU), an EHR-based, nested case-control study of 15,888 patients with new-onset T2D and of matched control participants in Pennsylvania. A census tract–level measure of neighborhood socioeconomic environment (NSEE) was developed as a community type-specific z-score sum. Baseline food-environment mediators included percentages of 1) fast-food restaurants and 2) food retail establishments that are supermarkets. Natural direct and indirect mediating effects were modeled; results were stratified across four community types: higher-density urban, lower-density urban, suburban/small town, and rural.

RESULTS

Across studies, worse NSEE was associated with higher T2D risk. In VADR, relative availability of fast-food restaurants and supermarkets was positively and negatively associated with T2D, respectively, whereas associations in REGARDS and G/JHU geographies were mixed. Mediation results suggested that little to none of the NSEE–diabetes associations were mediated through food-environment pathways.

CONCLUSIONS

Worse neighborhood socioeconomic conditions were associated with higher T2D risk, yet associations are likely not mediated through food-environment pathways.
Prolonged Glycemic Adaptation Following Transition From a Low- to High-Carbohydrate Diet: A Randomized Controlled Feeding Trial
Authors: Jansen Lisa T , Yang Nianlan , Wong Julia MW , Mehta Tapan S , Allison David B , Ludwig David S , Ebbeling Cara B
Published: February 2022

Objective:
Consuming ≥150 g/d
carbohydrate is recommended for 3 days before an oral glucose tolerance test
(OGTT) for diabetes diagnosis. To evaluate this recommendation, time courses of
glycemic changes following transition from a very-low-carbohydrate (VLC) to
high-carbohydrate (HC) diet were assessed by continuous glucose monitoring
(CGM).

Research
Design and Methods: After
achieving 15±3% weight loss on the run-in VLC
diet, participants (18-50 years; BMI: ≥27 kg/m2) were randomly
assigned for 10 weeks to 3 isoenergetic diets: VLC (5% carbohydrate, 77% fat), HC-Starch
(57%, 25%; with 20% refined grains), or HC-Sugar (57%, 25%; with 20% sugar). CGM
was done throughout the trial (n=64) and OGTT at start and end (n=41). All food
was prepared in a metabolic kitchen and consumed under observation.

Results:
 Glucose metrics
continued to decline after week 1 in HC-Starch and HC‑Sugar (p<0.05), but
not VLC. From weeks 2-5, fasting and 2-hr glucose (mmol/L per week) decreased in
HC-Starch (fasting: -0.10, p=0.001; 2-hr: -0.10, p=0.04). From weeks 6-9, 2-hr
glucose decreased in HC-Starch (-0.07, p=0.01), and fasting and 2-hr glucose
decreased in HC‑Sugar (fasting: -0.09, p=0.001; 2-hr: -0.09, p=0.003). The
number of participants with abnormal glucose tolerance by OGTT remained 10 (of
16) in VLC at start and end but decreased from 17 to 9 (of 25) in both HC
groups.

Conclusions:
Physiological adaptation
from a low- to high-carbohydrate diet may require many weeks, with implications
for the accuracy of diabetes tests, interpretation of macronutrient trials, and
risks of periodic planned deviations from a VLC diet.
Neighborhood Socioeconomic Environment and Risk of Type 2 Diabetes: Associations and Mediation Through Food Environment Pathways in Three Independent Study Samples
Authors: Thorpe Lorna E. , Adhikari Samrachana , Lopez Priscilla , Kanchi Rania , McClure Leslie A. , Hirsch Annemarie G. , Howell Carrie R. , Zhu Aowen , Alemi Farrokh , Rummo Pasquale , Ogburn Elizabeth L. , Algur Yasemin , Nordberg Cara M. , Poulsen Melissa N. , Long Leann , Carson April P. , DeSilva Shanika A. , Meeker Melissa , Schwartz Brian S. , Lee David C. , Siegel Karen R. , Imperatore Giuseppina , Elbel Brian
Published: February 2022

OBJECTIVES.
We examined whether relative availability of fast-food restaurants and
supermarkets mediates the association between worse neighborhood socioeconomic
conditions and risk of developing type-2 diabetes (T2D).

RESEARCH
DESIGN AND METHODS. As part of the Diabetes Location, Environmental Attributes, and Disparities (LEAD) Network, three academic institutions used
harmonized environmental data sources and analytic methods in three distinct
study samples: (1) the Veterans Administration Diabetes Risk (VADR) cohort, a
national administrative cohort of 4.1 million diabetes-free veterans developed
using electronic health records (EHRs); (2) REGARDS, a longitudinal
epidemiologic cohort with Stroke Belt region oversampling (n=11,208); and (3) Geisinger/Johns
Hopkins University (G/JHU), an EHR-based nested case-control study of 15,888
new-onset T2D cases with matched controls in Pennsylvania. A census tract-level
measure of neighborhood socioeconomic environment (NSEE) was developed as a
community type-specific z-score sum. Baseline food environment mediators
included percentage of: (1) restaurants that are fast-food, and (2) food retail
establishments that are supermarkets. Natural direct and indirect mediating
effects were modeled; results were stratified across four community types (higher
density urban, lower density urban, suburban/small town, rural).

RESULTS.
Across studies, worse NSEE was associated with higher T2D risk. In VADR, relative
availability of fast-food restaurants and supermarkets were positively and
negatively associated with T2D, respectively, whereas associations in REGARDS
and G/JHU geographies were mixed. Mediation results suggested that little to none
of the NSEE-diabetes associations were mediated through food environment
pathways.

CONCLUSIONS.
Worse neighborhood socioeconomic conditions were associated with higher T2D
risk, yet associations are likely not mediated through food environment pathways.
Osteocalcin and Risks of Incident Diabetes and Diabetic Kidney Disease: A 4.6-Year Prospective Cohort Study
Authors: Ye Xiaoqi , Yu Rong , Jiang Fusong , Hou Xuhong , Wei Li , Bao Yuqian , Jia Weiping
Published: February 2022

Objective

We aimed to examine the
relationship between osteocalcin (OC) and the risk of incident diabetes, as
well as investigate for the first time the relationship between OC and the risk
of incident diabetic kidney disease (DKD).

Research Design and
Methods

5396 participants without diabetes (referred to as
non-diabetes subcohort) and 1174 participants with diabetes and normal kidney
function (diabetes subcohort) at baseline were prospectively followed up. The
logistic regression and modified Poisson regression models were used to
estimate the relative risk (RR) of baseline OC levels with incident
diabetes and DKD.

Results

During a mean 4.6-year follow-up period, 296 cases of incident
diabetes and 184 cases of incident DKD were identified. In the non-diabetes
subpopulation, higher OC levels were linearly associated with a decreased risk
of diabetes (RR for one unit increase of loge transformed OC, 0.51
[95% CI, 0.35 to 0.76]; RR for the highest quartile versus the lowest quartile,
0.65 [95% CI, 0.44 to 0.95], P for trend <0.05). In the diabetes subpopulation,
OC levels were linearly inversely associated with incident DKD (RR for one unit
increase of loge transformed OC, 0.49 [95% CI, 0.33 to 0.74]; RR for
the highest quartile versus the lowest quartile, 0.56 [95% CI, 0.38 to 0.83] P
for trend <0.05), even independent of baseline eGFR and UACR. No significant
interactions between OC and different subgroups on incident diabetes or DKD
were observed.

Conclusions

Lower
OC levels were associated with an increased risk of incident diabetes and DKD.
Correlación entre los subfactores que conforman la variable apoyo para un sistema de gestión de calidad en una institución educativa
Authors: Sotelo Asef Jesús Guillermo , López Domínguez Sergio Iván , Carreón Gallegos Ernesto , Figueroa González Ernesto Geovani
Published: February 2022

Para este estudio el objetivo fue conocer la correlación entre los subfactores que integran los requisitos de apoyo (variable Apoyo) en una institución educativa de nivel superior del estado de Durango, México, y determinar qué relaciones existen entre estos. Los subfactores derivan de los siguientes factores: Recursos, Competencia, Toma de conciencia, Comunicación e Información documentada, todos contenidos en la norma ISO 9001:2015, capítulo siete, “Apoyo o requisitos de apoyo para un sistema de gestión de la calidad”, de la Organización Internacional de Normalización (ISO, por sus siglas en inglés). La ruta metodológica que se siguió para cumplir con el objetivo fue a través de un diseño no experimental, de enfoque cuantitativo, con análisis de correlación, descriptivo y de corte transversal. Se aplicó un instrumento, cuyo alfa de Cronbach fue de 0.974, a 400 trabajadores de una institución de educación superior. Entre los resultados, se encontraron 66 (100 %) correlaciones entre los subfactores, y 11 (16.7 %) de ellas arrojaron una buena y significativa correlación. Finalmente, se concluye que estas 11 buenas relaciones generan certeza en los requisitos de apoyo y cumplen con los requisitos de apoyo para un sistema de gestión de calidad.
Effects of fly ash, slag pozzolans, and polycarboxylate on mechanical properties of concretes and economical evaluation
Authors: Ahmadi E. , Zandi Y. , Vetr M. , Yazdi H.
Published: February 2022

In this research, steel furnace slag, fly ash and new synthesized polycarboxylate was used to replace cement in concrete composition. Concrete was made in three grades of 400, 450 and 500 using steel furnace slag, fly ash and polymer with different percentages of dry weight. Also, the amount of water to cement was selected as one of the effective parameters in concrete strength and production costs. The results showed that slag percent had a positive effect on improving samples strength. Also, increasing the percentage of polycarboxylate and decreasing the amount of water per cement ratio increased the strength of concretes. Finally, by examining the effect of several parameters on the strength of concrete, an economic evaluation was performed to manage the cost of increasing the strength of concrete. The results also indicated that with increasing percentage of resistance, the amount of costs increased in all three grades: 400, 450 and 500.
Comparison of Warming Efficiency of Greenhouse Solar Dryer with Four Distinct Design Implementations
Authors: Bhushan Mrigank , Murchikar Prof. Ashish
Published: February 2022

Drying is a technique for transferring warmth from a source to a product while also removing moisture from the product in a limited space. When using sun drying, the heat required for drying is primarily provided by solar energy. In this paper we have discussed about the fundamentals of different types of green house solar dryer, and to develop new design of solar dryer that would maximize warming efficiency. The main goal of this research is to run a computational fluid dynamics analysis on a previous model to analyze the influence of the highest warming within the greenhouse solar dryer.
Leisure Boredom Affects Gaming Disorder on Emerging Adult Smartphone Users
Authors: Yuwono Mario Rizky , Virlia Stefani
Published: February 2022

The risk of gaming disorder is not only limited to hardcore gaming style, but is also found in the increasingly popular casual gaming style. This study aims to test how leisure boredom affects gaming disorder in emerging adult smartphone users. A quantitative approach with correlational design was used in the study. The criteria of the respondents were individuals aged 18-25 years, who played games on their smartphones at least once a day and resided in Surabaya, Indonesia. A total of 175 respondents participated in this research. Modified version of the Leisure Boredom Scale (LBS) and the Internet Gaming Disorder - 20 Test (IGD-20 Test) were utilized to collect data. The data was analyzed using simple linear regression. The results indicated that leisure boredom may predict the tendency of gaming disorder in emerging adult smartphone users. The conflict aspect in gaming disorder was found to be the most affected by leisure boredom, whereas the mood modification aspect was found to be the only aspect not affected by leisure boredom.

Risiko akan kelainan bermain game tidak hanya terbatas pada gaya bermain intensif (hardcore gaming), namun juga pada gaya bermain santai (casual gaming) yang semakin populer. Studi ini bertujuan untuk menguji pengaruh rasa bosan di waktu luang terhadap kelainan bermain game pada pengguna smartphone dewasa muda. Pendekatan kuantitatif dengan desain korelasional telah digunakan dalam studi ini. Responden memiliki kriteria berusia 18-25 tahun yang bermain game di smartphone minimal satu kali dalam sehari dan berdomisili di Surabaya, Indonesia. Terdapat 175 responden yang bersedia mengikuti studi ini. Alat ukur Leisure Boredom Scale (LBS) dan Internet Gaming Disorder - 20 Test (IGD-20 Test) yang dimodifikasi telah digunakan untuk mengumpulkan data. Data dianalisis menggunakan regresi linear sederhana. Hasil menunjukkan bahwa rasa bosan di waktu luang memprediksi kecenderungan kelainan bermain game pada pengguna smartphone dewasa muda. Aspek conflict ditemukan sebagai aspek yang paling dipengaruhi rasa bosan di waktu luang sedangkan aspek mood modification ditemukan tidak dipengaruhi rasa bosan di waktu luang.
Guidelines on Conducting Online Experiments with Repeated Measures and Using Smartphone Applications
Authors: Permatasari Intan , Susianto Harry
Published: February 2022

In Indonesia, online research is typically conducted using survey design. Data collection is conducted by distributing links to questionnaires through social media. Compared to surveys, online experimental research, especially ones that utilize mobile applications and require repeated measures, are very rarely implemented. This is thought to be caused by the lack of experience among researchers of psychology in creating and managing online research platforms or smartphone applications. This article aims to guide researchers on conducting online experiments with repeated measures, integrated with additional smartphone applications that are available for free.

Di Indonesia penelitian secara daring umumnya dilakukan menggunakan desain survei. Pengumpulan datanya dilakukan dengan cara menyebarkan tautan kuesioner melalui media sosial. Dibandingkan survei, penelitian eksperimen daring, terlebih lagi yang menggunakan aplikasi ponsel dan membutuhkan pengukuran multipel sangat jarang dilakukan. Penyebabnya diduga karena peneliti psikologi umumnya belum terbiasa membuat serta mengelola platform penelitian daring atau aplikasi ponsel. Artikel ini bertujuan memberikan panduan melakukan eksperimen daring dengan pengukuran multipel (repeated measures) yang mengintegrasikan tambahan aplikasi ponsel yang bisa dilakukan secara gratis.
Leveraging the synergy between antimicrobial stewardship and infection prevention and control in fighting antimicrobial resistance
Authors: Sartelli Massimo
Published: February 2022

The COVID-19 pandemic had a great impact on the understanding of both antimicrobial stewardship (AS) and infection prevention and control (IPC). During the COVID-19 pandemic, the collaboration between AS and IPC has mitigated the shortcomings experienced by health systems around the world, enhancing the performance of both, reinforcing the synergy between them, and increasing their preparedness in fighting antimicrobial resistance. In planning the post-pandemic era, health systems worldwide should invest in reinforcing the synergy between AS and IPC highlighted during the pandemic.
Nitrogen gross balance in farms specialised in plant production in selected regions of Poland
Authors: KUPIEC JERZY , ZDANOWSKA AGNIESZKA , ZBIERSKA JANINA , WOŹNIAK ALEKSANDRA
Published: February 2022

The aim of the performed investigations was to evaluate nitrogen management in farms specialising in plant production situated in the following voivodeships: Wielkopolskie, Dolnośląskie, Opolskie and Mazowieckie. The analysed data were derived from 31 individual farms specialising in plant production situated in various regions and covered the period of 2004–2006. Farms from Wielkopolska and Dolny Śląsk were situated in nitrate vulnerable zones (NVZ’s). The nitrogen balance in farms located in NVZ’s, on average, amounted to 12.5 kg N ha-1 of agricultural land (AL). In the case of farms situated in Opolskie voivodeship, a significant deficit of this element was observed amounting to -63.3 kg N ha-1 of AL. Farmers from Raszyn commune in Mazowieckie voivodeship posed a potential hazard to the environment managing nitrogen resources in an irrational way. The nitrogen balance there exceeded the Code of Good Agricultural Practice (COGAP) recommended standard of 30 kg N ha-1 of AL reaching the level of about 50 kg N ha-1 of AL.
Tree height and species composition of young forest stands fifteen years after the large-scale wind disturbance in Tatra National Park
Authors: Šebeň Vladimír , Konôpka Bohdan
Published: February 2022

In November 2004, the windstorm Alžbeta damaged over 12 thousand ha of forests in the High Tatra Mts. It was the largest wind disaster in the modern forestry history of Slovakia. The process of forest regeneration at the post-disturbance area has to be monitored together with the effectiveness of implemented forestry measures. Therefore, we focused on tree measurements at 90 monitoring plots (MP) in 1 × 1 km net placed in the post-disturbance area in the Tatra National Park. We recorded tree species, number of trees (density) and tree heights. Besides that, stem diameters of trees with breast height diameter over 7 cm were measured. The field work was performed in the growing season of 2019, i.e. about 15 years after the wind disturbance. In total, 20 tree species, 15 broadleaves and 5 coniferous ones, were recorded at MP. The most frequent (28.9% of all trees) species was Norway spruce followed by silver birch (18.6%), rowan (16.9%) and goat willow (15.2%). Four species, i.e. European larch, wild cherry, grey alder and common alder contributed to the total number of trees between 1.8 and 4.8% each. Share of all other species together was about 5%. Tree height frequency was left-sided for the whole sampling set (all species together), as well as for individual species. Most of young trees were less than 1m high, but some of them exceeded 10 m. Further, tree density of over 100 individuals per are (100 m2) was found at 1/3 of all MPs. As many as 25% of MPs were characterized with tree densities between 61 and 90 individuals. At 23% of MPs, the number of trees was up to 30 individuals per are, and 20% of MPs had between 31 and 60 small trees per are. The results suggested that the post-disturbance forest stands in the High Tatras would be more resistant to wind storms and very probably also to bark beetles after reaching maturity than those, which were destructed and declined at the beginning of 21st century.
Degradación oxidativa por reacciones fotocalíticas: una alternativa para la mitigación de SARS-CoV-2
Authors: Lara Castro Miguel , Bautista Bautista Yessica , Woo García Rosa María , Bonilla Hernández Ana Carem
Published: February 2022

La fotocatálisis es una reacción química inducida por la absorción de un material sólido, o fotocatalizador. La excitación del sólido desencadena dos reacciones que conducen a la formación casi instantánea de radicales hidroxilos y aniones superóxido (llamadas especies reactivas de oxígeno; ROS). Los ROS producen daño oxidativo en diversos microorganismos incluyendo al virus SARS-CoV2, favoreciendo la desintegración de la conformación proteica de la cápside, cambios en la permeabilidad y daños de la membrana del virión que finalmente conduce a rotura del ADN, sin la oportunidad de reparación. Incluso, la reacción fotocatalítica causa la degradación oxidativa contra materiales peligrosos orgánicos y/o inorgánicos en el aire para convertirlos en sustancias no dañinas como agua o dióxido de carbono.
PENGARUH PERPUTARAN PIUTANG DAN PERPUTARAN PERSEDIAAN TERHADAP PROFITABILITAS
Authors: Friyanto Friyanto , Masrifah Fa’issa Barokatin , Saifuddin Saifuddin
Published: February 2022

Tujuan dalam penelitian ini, meliputi: untuk mengetahui dan menganalisis pengaruh perputaran piutang dan perputaran persediaan secara parsial terhadap profitabilitas pada perusahaan sub sektor makanan dan minuman yang terdaftar di Bursa Efek Indonesia periode tahun 2016-2020. Dan juga untuk mengetahui dan menganalisis pengaruh perputaran piutang dan perputaran persediaan secara simultan terhadap profitabilitas pada perusahaan sub sektor makanan dan minuman yang terdaftar di Bursa Efek Indonesia periode tahun 2016-2020.

Sampel dalam penelitian ini adalah laporan keuangan pada 9 (Sembilan) perusahaan sub sektor makanan dan minuman yang terdaftar pada Bursa Efek Indonesia periode 2016-2020 yang berjumlah 45 laporan keuangan yang dipilih menggunakan tehnik purposive sampling. Data yang digunakan adalah data sekunder yang diambil dari data www.idx.co.id. Penelitian ini menggunakan metode kuantitatif dengan tehnik analisis regresi berganda yang dibantu dengan menggunakan program aplikasi SPSS (Statistical Product and Service Solution) versi 20.

Hasil uji t yang pertama terbukti bahwa hipotesis secara parsial tidak berpengaruh terhadap variabel independen yaitu variabel perputaran piutang terhadap profitabilitas tidak terbukti kebenarannya. Sedangkan hasil uji t yang kedua terbukti bahwa hipotesis secara parsial berpengaruh terhadap variabel independen yaitu perputaran persediaan terhadap profitabilitas terbukti berpengaruh. Dan hasil analisis regresi dari uji F menunjukkan bahwa secara simultan atau bersama-sama terdapat pengaruh antara variabel perputaran piutang dan perputaran persediaan berpengaruh terhadap profitabilitas pada perusahaan sub sektor makanan dan minuman yang terdaftar di Bursa Efek Indonesia.
Procedural Drift: An Underappreciated Element of Clinical Treatment Fidelity
Authors: Cook Chad E. , Beneciuk Jason M. , George Steven Z.
Published: February 2022

Synopsis

Procedural fidelity involves delivering the correct guideline-supported treatment choice, in its designed manner, over the full care episode of the patient. Procedural drift is a subcomponent of procedural fidelity that involves performing the right treatment the right way initially, then drifting toward suboptimal treatment over time. Procedural drift occurs most often when providing intricate, patient-centered interventions that require attention to subtle nuances that potentially maximize their effectiveness. Drift comes from the belief that subtle nuances do not matter, or from a lack of motivation or incentive to maintain high fidelity. Strategies to reduce drift in practice include investment in early, high-quality training; using checklists and manuals when providing an intervention; using risk-adjusted patient data as a checks-and-balances system; and incorporating measures of drift in the practitioner's annual review. J Orthop Sports Phys Ther 2022;52(2):63–66. doi:10.2519/jospt.2022.10961
The incidence and risk factors of thromboembolism in patients with traumatic spine fractures in a tertiary care hospital
Authors: Eissa Abdullah T. , Alanagari Abdulaziz , Alrowaili Fahed , Aleissa Sami
Published: February 2022

Objectives:

Traumatic spine injuries may lead to devastating outcomes. One of the most common causes of death in these patients is thromboembolism, more with those who have risk factors. This study aimed to find out the incidence and associated risk factors of thromboembolism in traumatic spine fractures.

Methods:

This retrospective cohort study included all adult patients with traumatic spine fractures from 2007 to 2014 in King Abdulaziz Medical City in Riyadh. Significant differences in the occurrence of deep vein thrombosis (DVT) or pulmonary embolism (PE) in traumatic spinal fractures were looked for.

Results:

Out of 1128 patients with spine fractures, thromboembolism occurred in 73 (6.5%). In cervical spine fractures, DVT showed statistically significant association with the hospital length of stay, intensive care unit (ICU) length of stay, Glasgow Coma Scale (GCS), and motor vehicle accidents. On the other hand, PE was significantly associated with low GCS and longer ICU and hospital stays. In patients with lumbar fractures, DVT was highly correlated with longer hospital stay and ICU length of stay, low GCS, and severe injury severity score, while PE was highly correlated with high weight and longer hospital and ICU stay. Nevertheless, thoracic spine fractures victims have no significant association with any studied factors.

Conclusion:

The incidence of thromboembolism was 6.5% in patients with spine fractures. A longer hospital and ICU stay were the main factors that were correlated with increased risk of thromboembolism in cervical and lumbar traumatic spine fractures. However, thoracic spine fractures had no association with any studied factors.
Human Discomfort Index as a measure of biometeorological parameters influencing population: A study over selected cities of Andhra Pradesh
Authors: Chandu Kavitha , Akasapu Dharma Raju , Samudrala Venkata Jagannadha Kumar
Published: February 2022

The climate of a place influences human lives. The variations of meteorological parameters occur in space and time. While humans adapt to a particular environment, the variations in local weather to a greater degree of intensity can have far-reaching implications on the health and comfort of a specific place’s habitat. These variations that have a bearing on human health and comfort are assayed using specific indices known as Human Discomfort Indices (HDI). In this study, the authors attempted to analyze the biometeorological influences over the cities of Andhra Pradesh during the recent years 2011-2019 using the well-known Thom’s Human Discomfort Index (HDI).
Assessment and development of air quality forecasting models by the combination of PCA and ANN at metropolis Kolkata, India
Authors: Roy Abhisek , Sarkar Biswajit , Debsarkar Anupam , Dutta Amit , Chakrabarty Shibnath
Published: February 2022

PM10, PM2.5, SO2, NO2, Pb, As and Ni were monitored at Jadavpur, Kolkata over the time span of October 2016 to March 2017. The air quality of the study area was assessed in terms of air quality index (AQI) which is calculated on the assessed concentration of the pollutants. The result of the study showed significant seasonal variance and the ambient air of the study area is highly polluted in terms of particulate matters, NO2 and metallic pollutants. AQI study reveals that PM2.5 was found responsible for this degraded air quality of Kolkata. Principal component analysis (PCA) was used to identify possible contributors i.e. i) construction work, windblown dust, road dust and earth crust (variance- 28.98%); ii) automobile exhaust (variance- 20.47%); iii) brake wear source, road dust and tire wear (variance- 18.07%) of air pollution in the study area. Multiple linear regression (MLR) and feedforward backpropagation artificial neural network (FFBPANN) were used in combination with PCA to predict the future PM2.5 concentrations. Several performance indexes were used to assess the degree of accuracy and the magnitude of error in the model predicted values. Overall performance index establishes the fact that PCA-FFBP-ANN model most accurately predicts the future PM2.5 concentrations.
Green synthesis of benzaldehydes by the selective oxidation o benzyl alcohols using hexacyanoferrate (III) and bromate under phase transfer catalysis
Authors: Bashpa P. , Bijudas K.
Published: February 2022

The selective oxidation of benzyl alcohols and substituted benzyl alcohols was carried out in greener solvents like ethyl acetate and toluene by hexacyanoferrate (III) and bromate ions under phase transfer catalysis. Various phase transfer catalysts like tetrabutylphosphonium bromide, tetrabutylammonium bromide, tetrabutylammonium hydrogen sulphate, cetyltrimethylammonium bromide and tricaprylmethylmmonium chloride were used. A pinch of sodium tungstate dihydrate is added as a co-catalyst when bromate is used an oxidant and hexacyanoferrate (III) is used in presence of mineral acids. The products obtained were precipitated as their 2,4- dinitrophenylhydrazone, purified, weighed and the yield was found to be > 90 %. The products were recrystallized in ethanol and analyzed by melting point and by various spectral techniques. It was proved that corresponding benzaldehydes were formed and there was no further oxidation to corresponding acids. All the catalysts were found effective in bringing out the reaction but based on yield and ease of reaction, the order of reactivity is tricaprylmethylammonium chloride > tetrabutylphosphonium bromide > tetrabutylammonium bromide > tetrabutylammonium hydrogen sulphate > cetyltrimethylammonium bromide. The selective oxidation of benzyl alcohols is very difficult to proceed in organic solvents without the aid of a phase transfer catalyst. Yield of products is found to be slightly more in ethyl acetate than that in toluene due to difference in polarity.
PERMAINAN TRADISIONAL BAGI ANAK USIA DINI DI KALIMANTAN BARAT
Authors: Lukmanulhakim Lukmanulhakim
Published: February 2022

Wealth owned by the people of West Kalimantan (Kalbar) is a potential that needs to be maintained and developed, one of which is the wealth of traditional games. The focus of this research is to conduct an inventory of traditional games for early childhood in Kalbar. This study uses a qualitative approach. This research activity is located in Kalbar. The source of this research is the community consisting of: Community Leaders of Kalbar, Communities, children, parents. The research methods used were in-depth interviews, observation; and documentation studies. Analysis of qualitative research data through three stages that are mutually integrated, namely: reduction, display and verification. This study concludes that traditional Kalbar games have potential for early childhood development, namely Gasing, Jajak Sisir, Ukau, Jangkak Tempurung, Lantak/leletop, Tabak Oka/Dengkak, Jangko, Stabbing Rusak, Galah Kepung/Galasin, and Tapok Beleg/Canned. (1) The types of games found in the ten traditional games are divided into two types. namely solitary play and cooperative play. (2) The characteristics of the traditional games found are the cultural heritage of the Kalbar’s people. (3) The game is identical to the use of natural materials as a medium. (4) Each game has its own rules of play. (5) Traditional games have development potential for early childhood. Keywords: Traditional Games, Early Childhood, West Kalimantan AbstrakKekayaan yang dimiliki oleh masyarakat Kalimantan Barat (Kalbar) merupakan potensi yang perlu dijaga serta dikembangkan, salah satunya kekayaan permainan tradisional. Fokus penelitian ini adalah melakukan inventarisasi permainan tradisioanl bagi anak usia dini di Kalbar. Penelitian ini menggunakan pendekatan kualitatif. Kegiatan penelitian ini berlokasi di Kalbar. Sumber dari penelitian ini adalah masyarakat yang terdiri dari: Tokoh Masyarakat Kalbar, Komunitas-komunitas, Federasi Olahraga Rakyat Masyarakat Indonesia (FORMI), anak-anak, para orang tua. Metode penelitian yang digunakan adalah wawancara mendalam, observasi; dan studi dokumentasi. Analisis data penelitian kualitatif melalui tiga tahapan yang saling terintegrasi, yakni: reduction, display dan verification. Penelitian ini menyimpulkan bahwa permainan tradisional Kalbar menjadi potensi bagi pengembangan anak usia dini yaitu Gasing, Jajak Sisir, Ukau, Jangkak Tempurung, Lantak/ leletop, Tabak Oka/ Dengkak, Jangko, Tikam Rusak, Galah Kepung/ Galasin, dan Tapok Beleg/ Kaleng. (1) Jenis-jenis permainan yang ditemukan dalam sepuluh permainan tradisonal terbagi dalam dua jenis. yaitu solitary play dan cooperative play. (2) Karakteristik permainan tardisional yang ditemukan merupakan warisan budaya masyarakat Kalbar. (3) Permainan identik dengan pemanfataan bahan alam sebagai medianya. (4) Setiap permainan memiliki aturan bermainnya masing-masing. (5) Permainan tradisional memiliki potensi pengembangan bagi anak usia dini.
Bonding character, electron delocalization, and aromaticity of cyclo[18]carbon (C18) precursors, C18-(CO)n (n = 6, 4, and 2): Focusing on the effect of -CO groups
Authors: Wang Xia , Liu Zeyu , Yan Xiufen , Lu Tian , Xiong Weiwei
Published: February 2022

Although the unique cyclo[18]carbon (C18) realized by recent experiments has been greatly concerned, it has so far remained elusive. In contrast, its precursors C18-(CO)n (n = 6, 4, and 2), which can be separated stably, are of more practical significance. In this paper, the bonding character, electron delocalization, and aromaticity of the C18-(CO)n (n = 6, 4, and 2) with out-of-plane and in-plane dual π systems (πout and πin) perpendicular to each other are studied by combining quantum chemical calculations and wavefunction analyses. These cyclocarbon oxides exhibit alternating long and short C-C bonds and extensive electron delocalization, and a significant diatropic induced ring current under the action of external magnetic field is therefore observed, which reveals the aromatic characteristic in the molecules. The global electron delocalization and significant influence of the number of intramolecular carbonyl (-CO) on the two sets of π conjugated systems have been focused on, and the essential reason for the distinct difference in the overall aromaticity of the molecules was also clarified. It seems that the substituent -CO groups hinders the electron delocalization of the πin system but has relatively small effect on the πout system, resulting in the molecules with less -CO group showing greater aromaticity.
Thermodynamic and structural insights into the repurposing of drugs that bind to SARS-CoV-2 main protease
Authors: Wan Shunzhou , Bhati Agastya , Wade Alex , Alfe Dario , Coveney Peter
Published: February 2022

Although researchers have been working tirelessly since the COVID-19 outbreak, there is yet no effective drug found to directly treat the disease. Given the slow pace and substantial costs of new drug discovery and development, repurposing of existing drugs for the ongoing disease becomes an attractive proposition. In a recent study, a high-throughput x-ray crystallographic screen has been performed for the drugs which have been approved or are in clinical trials. 37 compounds have been identified from drug libraries, which bind to the SARS-CoV-2 main protease (3CLpro). In the current study, we use molecular dynamics simulation and an ensemble-based free energy approach, namely, enhanced sampling of molecular dynamics with approximation of continuum solvent (ESMACS), to investigate a subset of the aforementioned compounds. The drugs studied here are highly diverse, interacting with different binding sites and/or subsites of 3CLpro. ESMACS gives precise and reproducible free energy predictions, which agree well with experimental measurement. Our study also provides detailed energetic insight into the nature of drug−protein binding, which would shed light on the design and discovery of potential drugs.
Wide-field Surface-Enhanced Coherent Anti-Stokes Raman Scattering Microscopy
Authors: Zong Cheng , Cheng Ran , Chen Fukai , Lin Peng , Zhang Meng , Chen Zhicong , Yang Chen , Cheng Ji-Xin
Published: February 2022

Surface-enhanced Raman scattering (SERS) spectroscopy has been used extensively to study biology, chemistry, and materials. However, a point-by-point SERS mapping is time-consuming, taking minutes to hours for large-scale imaging. Here, we report a wide-field surface-enhanced coherent anti-Stokes Raman scattering (WISE-CARS) microscopy for monitoring nanotags in live cells and label-free detection of metabolic molecules. The WISE-CARS microscope achieves an imaging speed as fast as 120 frames per second for a large field of view of 130 microns X 130 microns. By spectral focusing of femtosecond lasers, a hyperspectral WISE-CARS stack of 120 frames can be acquired with a spectral resolution of 10 cm-1, where over 1 million Raman spectra are parallelly recorded within 0.5 seconds. As applications, we demonstrate time-lapse, 3D WISE-CARS imaging of nanotags in live cells as well as label-free detection of adenine released from S. aureus.
A SARS-CoV-2 aptasensor based on electrochemical impedance spectroscopy and low-cost gold electrode substrates.
Authors: Lasserre Perrine , Balansethupathy Banushan , Vezza Vincent J. , Butterworth Adrian , MacDonald Alexander , Blair Ewen O. , McAteer Liam , Hannah Stuart , Ward Andrew C. , Hoskisson Paul A. , Longmuir Alistair , Setford Steven J. , Farmer Eoghan C. W. , Murphy Michael E. , Flynn Harriet , Corrigan Damion K.
Published: February 2022

SARS-CoV-2 diagnostic practices broadly involve either qPCR based nucleic amplification or lateral flow assays (LFAs). qPCR based techniques suffer from the disadvantage of requiring thermal cycling (difficult to implement for low-cost field use) leading to limitation on sample to answer time, the potential to amplify viral RNA sequences after a person is no longer infectious and being reagent intense. LFA performance is restricted by qualitative or semi-quantitative readouts, limits on sensitivity and poor reproducibility. Electrochemical biosensors, and particularly glucose test strips, present an appealing platform for development of biosensing solutions for SARS-CoV-2 as they can be multiplexed and implemented at very low cost at point of use with high sensitivity and quantitative digital readout. This work reports the successful raising of an Opti-mer sequence for the spike protein of SARS-CoV-2 and then development of an impedimetric biosensor which utilises thin film gold sensors on low-cost laminate substrates from home blood glucose monitoring. Clinically relevant detection levels for SARS-CoV-2 are achieved in a simple, label-free measurement format using sample incubation times of 15 minutes. The biosensor developed here is compatible with mass manufacture, is sensitive and low-cost CE marked readout instruments already exist. These findings pave the way to a low cost and mass manufacturable test with the potential to overcome the limitations associated with current technologies.
A fast alternative to the galvanostatic intermittent titration technique
Authors: Chien Yu-Chuan , Liu Haidong , Menon Ashok S. , Brant William R. , Brandell Daniel , Lacey Matthew J.
Published: February 2022

The galvanostatic intermittent titration technique (GITT) has been regarded as the go-to method for determining the diffusion coefficients of Li-ions in insertion electrode materials at various states of charge (SoC). However, the method is time-consuming. In this work, the intermittent current interruption (ICI) method is demonstrated to provide comparably accurate measurements of diffusion coefficients with a drastically reduced experimental time. Theoretically, it is derived from Fick’s laws that the ICI method renders essentially the same information as GITT. Experimentally, both GITT and ICI are then compared side-by-side in a three-electrode half-cell of LiNi0.8Mn0.1Co0.1O2 (NMC811). It is shown that the results from both methods match where the assumption of semi-infinite diffusion applies. Moreover, the benefit of the non-disruptive ICI method to operando characterization methods is demonstrated via correlation of changes in the continuously monitored diffusion coefficient of Li+ in NMC811 to structural changes in the material by operando X-ray diffraction (XRD).
Structure-Activity-Relationship and Bioactivity of Neurotrophic trans-Banglene
Authors: Gohil Khyati , Kazmi M. Zain , Williams Florence
Published: February 2022

Neurotrophic small molecule natural products are functional analogs of signaling proteins called neurotrophins, which cause a pro-growth, pro-survival, or pro-differentiation response in neuronal cells. While these phenotypic responses are desirable to combat neurodegenerative disease progression, the pharmacokinetic properties of neurotrophins present challenges to their administration. Therefore, neurotrophic small molecules such as the cis- and trans-banglenes offer attractive alternatives. We describe the synthesis and testing of banglene derivatives and establish a structure-activity response for the banglene family. We demonstrate that (–) trans-banglene is the primarily active enantiomer, and that select modifications on the cyclohexene ring of trans-banglene do not significantly impair its bioactivity. Finally, we demonstrate that (–) trans-banglene potentiation of NGF induced neuritogenesis is unaffected by the presence of these Erk1/2, Akt and Pkc inhibitors. Our structure-activity results also suggest that (–) trans-banglene neurotrophic activity and its potentiation of NGF activity might be distinct unassociated processes.
Simultaneous simulation and optimization of multiple dividing wall columns
Authors: Seidel Tobias , Ränger Lena-Marie , Grützner Thomas , Bortz Michael
Published: February 2022

In this work we present a new approach that we use to simulate and optimize multiple dividing wall columns at the same time. Instead of considering all model equations as constraints and all process variables as optimization variables in a large and highly nonlinear optimization problem we only incorporate a subset of the model equations as constraints and a subset of the process variables as optimization variables. The remaining process variables are calculated from this subset by a robust and fast calculation procedure. This calculation procedure also ensures that the remaining model equations are satisfied. A comparison with the commercial process simulator Aspen Plus shows that with the new approach multiple dividing wall columns can be optimized more stable and better solutions are found. Moreover the time needed to find an optimal design decreases significantly.