bluuebunny/crossref_metadata_2025 huggingface dataset:
PERAN KELOMPOK TANI DALAM MENINGKATKAN PENDAPATAN PETANI PADI SAWAH DI DESA BANTAYAN KECAMATAN LUWUK TIMUR
Authors: Anggo Hardi ,   Program Studi Agribisnis Fakultas Pertanian Universitas Tompotika Luwuk, Djamaluddin Ismail , Yatim Hertasning ,   Program Studi Agribisnis Fakultas Pertanian Universitas Tompotika Luwuk,   Program Studi Agroteknologi Fakultas Pertanian Universitas Tompotika Luwuk
Published: July 2024

Paddy rice is one of the most widely consumed staple foods around the world including the Banggai Regency area. Thus, the role of farmers is very important in farming to maintain the availability of food. Apart from that, the income of farmers is also important in determining the level of welfare of these rice farmers. Thus, this study aims to determine the role of farmer groups and determine the income of paddy rice farmers in Bantayan Village, East Luwuk District, Banggai Regency. The research was conducted from June to August 2023 in Bantayan Village, East Luwuk District, Banggai Regency. The determination of this location was done deliberately with the consideration that Bantayan Village is one of the rice-producing villages. This research uses Likert scale and income analysis methods. The results obtained, namely, the role of farmer groups in disseminating information obtained (73.14%), the provision of facilities and means of production (70.9%), planning activities (75.5%), the application of five farming technologies (70.9%), and cooperation with KUD institutions (88%), which means all the activities of rice paddy farmer groups in the village of Bantayan District East Luwuk classified as very active and high category. In addition, based on the analysis of income from the total income of farmers in Bantayan Village, East Luwuk Subdistrict obtained from the reduction between total revenue (TR) of IDR. 28,656,000 and total costs (TC) of IDR. 2,441,229, then the income (π) = TR - TC is IDR. 26,214,771. thus, rice paddy farming can still be continued to be cultivated because the amount of income obtained is quite high and profitable.
Parameter Estimation using Integral Equations
Authors: Lemaire François , Roussel Louis
Published: July 2024

We investigate the interest of using nonlinear integral equations insteadof nonlinear differential equations in a modelisation context.In particular, we perform parameter estimation on an academic exampleusing different input-output differential and integral equations.
Maple Conference 2023 Mathematical Art and Creative Works Exhibit
Authors: May John
Published: July 2024

The report from the curator on the third Maple Art and Creative Works Exhibit that took place as part of the 2023 Maple Conference.
A Short History of Maple Through a Biography of Stefan Vorkoetter
Authors: DeMarco Paul
Published: July 2024

For three decades at Maplesoft, Stefan Vorkoetter held many roles including being the main kernel developer.   This article walks through some of the early history of the company and the Maple project, highlighting Stefan’s involvement.
Perovskite Type Lanthanum Oxide and Graphene Oxide (LaFeO3-GO) Composite as (Low Overpotential) ORR Catalyst for Low and High Temperature Fuel Cells
Authors: Irfan Muhammad , Jamil Irum , Ahmad Fawad , Alamri Hatem , Buzdar Summi , Ali Sakina
Published: July 2024

Due to depletion of fossil fuel and their environmental effect, renewable resources are the prime interest in which fuel cell technology competes with fossil fuels but their ORR at cathode restrict its efficiency. Perovskite type orthorhombic structure of LaFeO3 incorporated GO has ability to use as catalyst in low and high temperature fuel cells having non-agglomerated particles in nanometers range (20- 100), high temperature stability, low overpotential of about 0.6V, ECSA of about 13.22 m2g-1 and current density of about 0.012 mAcm-1. Results open further research directions in supercapacitors, batteries, biological fuel cells, and applications which requires high temperature stability.
Research on Residential Interior Design and Energy Saving Optimization with Sustainable Low-carbon Development
Authors: Wang An , Wang Juanfen
Published: July 2024

The escalating crisis of global warming, driven by the emission of greenhouse gases, poses a formidable challenge for humanity as a whole. Notably, the construction industry contributes significantly to the global greenhouse gas inventory. Consequently, prioritizing low-carbon construction assumes paramount importance in mitigating the pervasive impact of the greenhouse effect on a global scale. Such an endeavor stands as a crucial safeguard for ensuring the sustainable development of human civilization. Therefore, from the perspective of low- carbon building design optimization research is an important part of low-carbon building. From the perspective of architectural design, this paper summarizes that low-carbon building design should pay attention to following aspects: reasonable use of natural lighting and natural ventilation, reduce the carbon emission value of building use stage; Taking the transformation project of the former engineering Institute of Southeast University as an example, this paper probes into the effect of design optimization on reducing carbon emissions, and quantitatively studies the relationship between the design optimization of lighting, ventilation and envelope structure materials and the reduction of building carbon emissions. The Angle selection of roof skylight is studied from the Angle of day- lighting optimization, the size and position of facade opening and the strategy of natural ventilation path are studied from the Angle of ventilation optimization. The indoor ventilation further reduces the refrigeration energy consumption, which is 22.1% less than before the renovation, and the roof reduces the heat gain by 22%-32%.e.
Microbial Quality of Water Used as Drinking Sources in Urban and Rural Households of Gujarat, India: A Cross-Sectional Study
Authors: Lakhani Sucheta , Shah Neil , Bhalodia Nidhi
Published: July 2024

INTRODUCTION: Globally nearly 2 billion people have no access to safely managed drinking water services and over 1.7 billion lack adequate or basic sanitation facilities. India is a growing and developing nation and the quality of ground water and drinking water needs to be regularly monitored. There are several diseases in India that spread due to contaminated water. Annually about 37.7 million Indians are affected by waterborne diseases.
AIMS AND OBJECTIVES: This research has been undertaken with the Aim and Intent to study, test, assess, evaluate and understand the aspects of Microbial quality of water used as drinking sources in urban and rural households.
MATERIAL AND METHODS: The 40 numbers of drinking water samples were collected.20 water samples from the urban area of Vadodara city and 20 water samples from the rural areas on outskirts of Vadodara city. Multiple Tube Fermentation Technique was used for detecting presence of coliforms. The free residual Chlorine was measured by use of Chloroscope equipment
RESULTS: A total of about 17 water samples (11 rural samples of untreated water and 06 urban samples of treated water) showed a higher MPN. The growth of E. coli which indicates the fecal contamination rate was noted in 09 water samples which is about 22.50% (09 water samples - 06 rural samples and 03 urban samples). The absence of fecal streptococci, E. coli and total coliforms was found in only 6 samples which is about 15.00%.
CONCLUSION: Pathogens, coliforms and other microorganisms were found in water samples collected from both urban as well as rural areas. It is now important to educate and bring awareness among local people about quality of their water source, the importance of clean surrounding near water source, boiling of drinking water to eliminate contamination.

Key words: Fecal coliforms, E. coli, Chloroscope
A Pre-Experimental Study to Assess the Effectiveness of Information Booklet on Knowledge Regarding Growth and Development of Infants Among Parents at Selected Rural Area, Udaipur, Rajasthan
Authors: Pujari Sonika , Pujar Jitendra , Kumawat Harish Kumar
Published: July 2024

Background: Infancy is a critical stage marked by rapid physical and cognitive changes. Development involves the emergence of new abilities and capacities, progressing through stages of maturity. Caregivers' understanding of growth and development aids in anticipating and addressing children's needs, detecting deviations from the norm, and facilitating early intervention for developmental issues. Therefore, present study aimed to assess impact of an information booklet on infant growth and development among parents.
Method: This study utilized a quantitative, pre-experimental design to gauge the impact of an information booklet on infant growth and development among parents in Bedwas, Udaipur. The sample comprised 60 parents of children under five from the selected rural area, chosen via non-probability purposive sampling. Data collection involved socio-demographic information and a structured knowledge questionnaire, with analysis conducted using descriptive and inferential statistics.
Results: The pre-test showed that 56.7% had poor knowledge, while 43.3% had average knowledge. In the post-test, 68.3% demonstrated good knowledge, while 31.7% had average knowledge. Mean pre-test knowledge score was 11.20±2.98, and mean post-test score was 21.52±2.50, with a significant mean difference of 10.32 (t=21.29, df=59, p=0.001). The information booklet effectively improved knowledge on infant growth and development. Demographic variables did not show significant associations with knowledge levels among parents.
Conclusion: The study concluded that the information booklet effectively enhanced parents' knowledge on infant growth and development. Understanding these changes prepares caregivers to actively guide early learning, crucial for later development. The findings emphasize the importance of educating mothers on nutrition and infant growth. Implementing educational programs can further enhance mothers' understanding of nutrition's role in infant development.

Key words: Knowledge, Parents, Infants, developmental milestone, Information Booklet
Prototype Development of Offloading Knee Brace for Management of Knee Osteoarthritis: A Case Study
Authors: Swami Pinki , Saharawat Sakshi
Published: July 2024

Background: Osteoarthritis (OA) of the knee is a degenerative joint condition characterized by the gradual deterioration of the cartilage in the knee joint commonly affecting the medial compartment of knee joint due to the increased load bearing during various activities. As the cartilage diminishes, the bones in the medial compartment may start rubbing against each other, causing discomfort, pain, stiffness in the joints, reduced range of motion, quadriceps muscle weakness, joint instability which may cause a feeling of wobbliness or unsteadiness, making it more difficult for individuals to maintain balance and stability during movement and changes in proprioception. Different types of knee orthosis can be beneficial in the management of OA. The currently available knee orthoses are useful for offloading the medial compartment of the knee, but are highly expensive, unaffordable for most people in developing nations like India. Hence the study aims to develop an effective intervention that does not involve surgery or pharmaceuticals, providing alternatives for those who may prefer or cannot undergo more invasive treatments. A new offloading knee brace was developed at Indian Spinal Injuries Centre, which was designed appropriately providing potential to reduce symptoms, improve joint function, improve balance and enhance overall well-being. The developed new offloading knee brace is an economical solution for the patients as well as the findings of the study will help the orthotist to have an option for an appropriate knee brace for successful treatment of person with medial knee osteoarthritis.
Objective: To develop a light weight and cost – effective offloading knee brace to assess the effects on balance and strength in patients suffering from medial osteoarthritis.
Study design: Case report
Significance: Unfortunately, the braces available are costly and unaffordable for Indian population, therefore the attempt was made to reduce the cost of the brace and the spiral design in new offloading brace resolve the balancing issues and improve the muscle strength of knee osteoarthritis.
Method: A 45-year-old male with osteo knee arthritis of medial compartment of grade 2 (mild) was assessed and pre – test reading for balance and strength was done. The subject was then provided with new offloading knee brace for a period of 1 week, post – test for balance and strength was recorded.
Result: The result shows a significant improvement in five – time sit to stand test, stair climb test, 6 - minute walk test, timed up and go test and lift and carry test thereby indicating improvement in balance and strength after the use of the brace.
Conclusion: The offloading knee brace was effective in improving the balance and strength in person with medial knee osteoarthritis.

Key words: Osteoarthritis, Balance, Strength, Knee orthosis, Offloading knee brace.
Técnicas avanzadas de superficies: Segunda entrega
Authors: Armendáriz Mireles Eddie Nahúm , Rocha Rangel Enrique
Published: July 2024

El propósito del presente proyecto editorial académico se enfoca en la técnica de diseño por superficies de productos mediante prácticas guiadas paso a paso, con una temática en técnicas de desarrollo de patrones a partir de varias metodologías de desarrollo. En cada capítulo se albergan temáticas de las líneas de investigación de los autores, desarrollo de productos, la aplicación de materiales y la bioinspiración en la naturaleza para resolver problemas cotidianos de la sociedad. Las ventajas de diseñar con superficies es que, al no poseer espesor, no es necesario preocuparse por el volumen de la pieza. Esto nos facilita el trabajo, ya que únicamente debemos preocuparnos por la forma externa de nuestra pieza y no por su interior. Posteriormente, a la pieza se les puede dar volumen, convertirla así en un sólido y poder manufacturar el producto. Los diseños de multicuerpos y superficies son aquellos que nos darán el mejor resultado para solucionar o definir modelados. El diseño a través de superficies se reduce a operaciones muy básicas, se puede conseguir resultados adecuados y de alta gama en complejidad, ergonomía y anatomía. Finalmente, se tiene la certeza que madurará en los conocimientos y el dominio de superficies como una herramienta de un innovador, desarrollador y diseñador e ingeniero, pues son fundamentales hoy en día, ya que estas temáticas fortalecerán las creaciones futuras de cada ojo creativo. “El diseño es donde la ciencia y el arte se equilibran”.
Cinco Orientações para o Ensino das Ciências. A Dimensão CTS no Cruzamento da Didática e de Políticas Educativas Internacionais
Authors: Mendes Alcina , Martins Isabel
Published: July 2024

A investigação em educação em ciências tem produzido conhecimento que permite compreender os problemas e fundamentar decisões de ensino das ciências. Algumas organizações internacionais (como UE, OCDE e UNESCO) também têm emitido documentos reguladores de políticas globais de ensino das ciências, assumindo que a qualidade da educação científica é uma condição de prosperidade económica e social dos estados. Neste estudo procedeu-se à revisão sistemática de documentos de natureza académica e de natureza política, relativos ao ensino das ciências, visando identificar quais os seus pontos de convergência. Apurou-se o referencial Cinco Orientações para o Ensino das Ciências, que identifica aspetos-chave a priorizar no ensino das ciências e na formação de professores. Verificou-se que as orientações de ensino das ciências de cariz CTS permanecem um campo didático promissor e atual do ponto de vista académico e político.
Práticas Integradas de Educação em Ciências. Um Programa de Formação Contínua para Professores com Cariz CTS
Authors: Rodrigues Ana , João Patrícia
Published: July 2024

O estudo que se apresenta teve como principal finalidade conceber, implementar e avaliar um programa de formação contínua para professores do 1.º Ciclo do Ensino Básico na área da Educação em Ciências. Este programa de formação visou a promoção de competências de planificação, implementação e avaliação de práticas integradas de educação formal e não- formal em ciências com enfoque CTS. O estudo contou com a participação de 12 professores- formandos da Escola Ciência Viva de Vila Nova da Barquinha, a única escola do 1.º Ciclo em Portugal que tem nas suas instalações um Centro Integrado de Educação em Ciências. Como técnicas de recolha de dados optou-se pelo inquérito por questionário, observação participante e compilação documental. Os dados foram analisados com recurso à técnica de análise de conteúdo através de um sistema categorial misto. A análise dos dados aponta para o facto dos professores-formandos terem desenvolvido diversas aprendizagens, nomeadamente a nível: das orientações de Educação em Ciências; da gestão dos processos de ensino e de aprendizagem das ciências; e da avaliação das aprendizagens das crianças. Este estudo aponta assim no sentido de que o programa de formação desenvolvido foi potenciador do desenvolvimento profissional dos professores-formandos, em particular, no que respeita a um incremento e melhoria das suas práticas integradas de educação formal e não-formal em ciências.
A rare presentation of hyperthyroidism: T3 thyrotoxicosis related to bilateral pitting edema of the leg
Authors: Kang Jieun ,   Internal Medicine Department, Bethesda Medical Centre Kampala, Uganda., Frederick Nelson Nakawagala ,   Internal Medicine Department, Bethesda Medical Centre Kampala, Uganda.
Published: July 2024

Thyrotoxicosis is a clinical state of inappropriately high levels of circulating thyroid hormones (T3 and/or T4) in the body from any cause. In the literature, bilateral pretibial pitting edema in hyperthyroidism cases has been reported in a few case reports. We report a case of T3 Thyrotoxicosis who had leg swelling for three weeks and whose finding regressed rapidly with treatment. Diffuse, bilateral pitting pretibial edema, which may occur due to many etiologies, should also be considered in the differential diagnosis of hyperthyroidism.
Central nervous system vasculitis secondary to sarcoidosis presenting with hemorrhagic stroke
Authors: Roçi Ermir ,   Neurovascular Service, “Mother Teresa” University Medical Center, Tirana, Albania., Dodaj Stela , Enesi Eugen , Vyshka Gentian ,   Neurovascular Service, “Mother Teresa” University Medical Center, Tirana, Albania.,   Department of Neuroradiology, University of Medicine in Tirana, Albania.,   Biomedical and Experimental Department, University of Medicine in Tirana, Albania.
Published: July 2024

A sixty-two year old woman, under treatment since five years for lung sarcoidosis, presented in the ER of our facility with severe thunderclap headache and hypertensive crisis. The ongoing corticoid therapy (twenty milligrams of oral prednisolone daily), well tolerated before, was discontinued and the patient underwent an unenhanced brain CT scan.
Construction of an Area-wide Management System for Transboundary Pest: The Case of Global Coordination and Its Implications for China
Authors: Fan Yang
Published: July 2024

Transboundary pests have posed a serious threat to food security in recent years, with outbreaks and rapid spread all over the world. For this reason, global transboundary pest management has made some progress with the support of the Food and Agriculture Organization of the United Nations (FAO). However, unresolved issues remain, such as the lack of relevant incentive and constraint rules, availability and long-term effectiveness of the technology to be improved, and lack of funds and financing mechanisms. Therefore, at the global level, relevant incentives and constraint mechanisms, increasing aid to developing countries, and the formulation of long-term global area-wide pest management programs should be developed. Furthermore, China's domestic area-wide pest management system and farmland ecological diversity should be developed to alleviate the dilemma of global cooperative transboundary pest control caused by common-pool resources.
Future Prospects and Recent Advancements in Machine Learning for Assessing the Service Life and Durability of Reinforced Concrete Buildings
Authors: Reena Kumari
Published: July 2024

For necessary action to be taken in a timely and economical way, accurate service-life forecast of buildings is essential. But the oversimplified assumptions of the traditional prediction models result in approximations that are not correct. The capacity of “machine learning” to overcome the shortcomings of traditional future models is reviewed in this research. This can be attributed to its capacity to represent the intricate physical and chemical dynamics of the degradation mechanism. The study also summarizes other studies that suggested “machine learning” may be used to support the assessment of reinforced concrete building durability. Comprehensive discussion is also held regarding the benefits of using machine learning to evaluate the service life and durability of “reinforced concrete” buildings. It is becoming easier to apply “machine learning for durability and service-life” evaluation thanks to the growing trend of wireless sensors gathering an increasing amount of in-service data. In light of the most recent developments and the state of the art in this particular field, the presentation ends by suggesting future directions.
Inverse Double Domination in Graphs
Authors: Vinodh Kumar A. R.
Published: July 2024

A vertex set  is a double – dominating set, if each vertex  is adjacent to at least two vertices in . The minimum cardinality of a double dominating set of G, denoted by  is called the double domination number of G.
A double dominating set S of a graph  is an inverse double dominating set, if  contains a double dominating set say of . Then  is called an inverse double dominating set. The inverse double domination number  of  is the minimum cardinality of an inverse double dominating set.
In this paper, we obtain exact value of  for some standard graphs and also, we establish some general results on this parameters.
DOI: https://doi.org/10.52783/tjjpt.v45.i03.7347
Sr. Kojirō Mizuno: Primer japonés en el caribe y pionero de la inmigración nipona en Colombia
Authors: Hernández Movilla Daniela
Published: July 2024

"Es entonces cuando en 1915, el Sr. Kojirō Mizuno llegó en barco a la biodiversa Colombia, convirtiéndose así en el primer japonés en llegar al caribe colombiano y el segundo nipón del cual se tenga registro de ingreso al país. Mizuno arribó al imponente muelle de Puerto Colombia, el primer puerto marítimo del país y el quinto más grande del mundo para entonces. El muelle era la entrada de diversos inmigrantes al Atlántico, por lo cual se le atribuye a Barranquilla el sobrenombre de “La puerta de oro”. Desde allí, cuenta mi tío abuelo, el Sr. Hermes Torres Mizuno, con la manera descomplicada y característica de los costeños de hablar, que mi tatarabuelo se trasladó durante 5 días montado en un burro, el cual era un medio de transporte muy común, para llegar a Usiacurí. Comprobó que las aguas curativas no eran un mito fantasioso, sino que los pozos de agua sulfhídricas tenían las propiedades medicinales que lograron aliviar todos sus síntomas estomacales. "
The Phenomenon of Collectible Design: the European and Russian Experience
Authors: Шевчук А.А.
Published: July 2024

Функционализм и рационализм, как базовые проектные качества дизайна, в современном обществе «эмоционального капитализма» перестали отвечать актуальным потребительским запросам. Дизайн в современном мире стремится решить более нематериальные вопросы, связанные с эмоциональной, интуитивной парадигмой восприятия мира, используя художественные ресурсы. На стыке искусства и дизайна возникает и формируется новое русло дизайна — коллекционный дизайн. Как новое, только обретающее форму, но уже востребованное явление, коллекционный дизайн требует изучения, выявления характерных особенностей и принципов проектирования. Данное исследование — это попытка в первом приближении осмыслить природу данного феномена, понять, какое место он занимает в индустрии, и спрогнозировать его развитие в эволюционных процессах дизайна.

Design has long ceased to be only an effective functional solution to a problem, and is more and more often perceived as art. In the modern world design seeks to solve intangible issues relating to the emotional and intuitive part of the perception of the world through artistic means. At this intersection of art and design, collectible design is emerging and developing as a new line of design that is just beginning to acquire a formulated, generally accepted and understandable form. A new phenomenon in the industry and already much sought after, collectible design needs to be researched. By identifying its defining characteristics and principles of design, we can gain a better understanding of its nature as a phenomenon and its role within the industry.
Computer Adaptive vs. Non-adaptive Medical Progress Testing: Feasibility, Test Performance, and Student Experiences
Authors: Van Wijk Elise V. , Donkers Jeroen , De Laat Peter C. J. , Meiboom Ariadne A. , Jacobs Bram , Ravesloot Jan Hindrik , Tio René A. , Van Der Vleuten Cees P. M. , Langers Alexandra M. J. , Bremers Andre J. A.
Published: July 2024

Background: Computerized adaptive testing tailors test items to students’ abilities by adapting difficulty level. This more efficient, and reliable assessment form may provide advantages over a conventional medical progress test (PT). Prior to our study, a direct comparison of students’ performance on a computer adaptive progress test (CA-PT) and a conventional PT, which is crucial for nationwide implementation of the CA-PT, was missing. Therefore, we assessed the correlation between CA-PT and conventional PT test performance and explored the feasibility and student experiences of CA-PT in a large medical cohort.
Methods: In this cross-over study medical students (n = 1432) of three Dutch medical schools participated in both a conventional PT and CA-PT. They were stratified to start with either a conventional PT or CA-PT to determine test performance. Student motivation, engagement and experiences were assessed by questionnaires in students from seven Dutch medical schools. Parallel-forms reliability was assessed using the Pearson correlation coefficient.
Results: A strong correlation was found (0.834) between conventional PT and CA-PT test performance. The CA-PT was administered without system performance issues and was completed in a median time of 83 minutes (67–102 minutes). Questionnaire response rate was 31.7% (526/1658). Despite a higher experienced difficulty, most students reported persistence, adequate task management and good focus during the CA-PT.
Conclusions: CA-PT provides a reliable estimation of students’ ability level in less time than a conventional non-adaptive PT and is feasible in students throughout the entire medical curriculum. Despite the strong correlation between PT scores, students found the CA-PT more challenging.
Antioxidant activities of an iridoid-rich beverage containing noni juice, cornelian cherries, and olive extract in vitro and in human volunteers
Authors: Brett J. West  , Shixin Deng
Published: July 2024

Plant-based foods are dietary sources of antioxidant compounds that are helpful in preventing or alleviating oxidative stress. Iridoids are a class of secondary plant metabolites with antioxidant activities. An iridoid-rich beverage, Tahitian Noni® Max (Max), that contains Morinda citrifolia (noni) juice, Cornus mas (cornelian cherry) fruit purée, and Olea europaea (olive) extract was evaluated for antioxidant activity in vitro and in healthy nonsmoking young adult volunteers. Iridoid analyses were also performed via high performance liquid chromatography (HPLC) with samples of Max to confirm the presence of deacetylasperulosidic acid, asperulosidic acid, scandoside, loganic acid, and oleuropein. The oxygen radical absorbance capacity (ORAC) assay results reveal that Max possesses notable antioxidant potential, with four times more in vitro antioxidant potential than pasteurized blood orange juice. In the human trial, all participants in the Max group experienced increases in erythrocyte and plasma antioxidant activities within 40 minutes of ingestion. Further, the average erythrocyte antioxidant activity of this group increased approximately 28 times more, and just over 49 times more for average plasma antioxidant activity, than those in a blood orange juice control group (P < 0.001). The findings of the current study indicates that Max is a significant dietary source of iridoids and improves the antioxidant activity of components of the blood within 40 minutes of ingestion.
Asma Islahında Son Gelişmeler ve Güncel Metotlar
Authors: Bozkuş Şeyma , Bozkuş Mücahid
Published: July 2024

Asma (Vitis vinifera subsp. vinifera), dünya genelinde en yaygın ve ekonomik olarak yetiştiriciliği yapılan çok yıllık meyve türlerinden biridir. Asma ürünlerinin insan sağlığı üzerindeki olumlu etkilerinin bilinmesiyle, dünyadaki bağ alanlarında istikrarlı bir artış görülmüştür. Değişen çevresel koşullar ve pazar talepleri doğrultusunda yıllar içinde değişen bağcılık sektöründe yeni çeşitlerin geliştirilmesiyle üzümün pazardaki sürdürülebilirliği sağlanmıştır. Bu bağlamda, biyoteknoloji ve genetik mühendisliği alanındaki gelişmeler üzüm verimliliğini ve kalitesini arttırmada etkili bir araç olarak ortaya çıkmıştır. Genetik biliminin sağlamış olduğu metotları klasik asma ıslahı sürecine dâhil etmek, meyve kalitesinin arttırılması, biyotik ve abiyotik stres şartlarına karşı dayanıklı asma türlerinin daha hızlı geliştirilmesine olanak sağlamaktadır. Bu derlemenin amacı, asma ıslahında geçmişten günümüze kadar olan süreçler ve kullanılan önemli metotlar ile ilgili bir perspektif sunmak ve yeni teknolojilerin asma genetiğinin iyileştirilmesi potansiyeli hakkında bilgi vermektir.
Quel enseignement de l’informatique à l’école primaire en France ? Réflexions sur 40 ans de développements
Authors: Baron Georges-Louis
Published: July 2024

Ce texte présente d’abord une brève analyse de l’introduction et de la diffusion de l’informatique en tant qu'objet d'enseignement à l’école primaire depuis le début des années 1980. Il décrit un parcours lent et marqué de changements d’orientations, l’informatique étant considérée par l’institution scolaire selon les moments plutôt comme mode de pensée ou comme ensemble d’outils. Si une discipline informatique de second degré a été instituée en France en 2020, l’autorité pédagogique ne semble actuellement pas disposée à renforcer ses instructions relatives à la prise en compte de l’informatique comme objet de connaissance et de culture à l’école primaire. Dans un second temps, on présente des points de repère sur la constitution d’une communauté francophone de recherche sur la didactique de l’informatique ainsi que des réflexions sur ce que peut apporter la recherche participative en termes de problématisation de la question de l’informatique à l’école primaire.
МЕТАБОЛИЗМДІК СИНДРОМЫ БАР АДАМДАРДА ТАМАҚТАНУ ТӘРТІБІ МЕН ӨМІР САЛТЫ БҰЗЫЛЫСТАРЫНЫҢ РӨЛІ (ӘДЕБИ ШОЛУ)
Authors: Турманбаева А.А. , Нускабаева Г.О. , Садыкова К.Ж. , Саруаров Е.Г. , Неметова Д.Б. , Айдарбекова Д.Н.
Published: July 2024

Қазіргі таңда медицинада метаболизмдік синдром өзекті мәселе болып қала береді және ол жыл сайын жасару тенденциясында. Дүниежүзілік денсаулық сақтау ұйымының сарапшылары метаболизмдік синдромды «ХХІ ғасырдың пандемиясы» деп сипаттады. Метаболизмдік синдром — ересек популяциялар арасында таралуы жоғары және бүкіл әлем бойынша қоғамдық денсаулық сақтау жүйелері үшін жоғары шығындары бар кардиометаболикалық қауіп факторларының бірі.ДДҰ деректері бойынша ересек популяцияда МС жиілігі 20-40% құрайды, ал келесі 20 жылда ол 50% артуы мүмкін. Mетаболизмдік синдромның жоғары жиілікте таралуына байланысты оны ерте анықтауасқынулардыуақтылы алдын алуды үшін үлкен маңызға ие. Зерттеудің мақсаты: метаболизмдік синдромның дамуындағы тамақтану бұзылыстарының, өмір салтының рөлін зерттеу үшін әдебиеттерге шолу жасау. Іздеу стратегиясы. Әдебиеттерді шолу барысында PubMed, Medline, Google Scholar, Embase, Web of Science ғылыми дерекқорларынан 2018 жылдан 2024 жылға дейін жарияланған мақалалар талданды. Іздеу үшін «метаболикалық синдром», «семіздік», «гиподинамия», «тамақтану тәртібі», «тамақтану режимі», «салауатты өмір салты» кілт сөздері қолданылды. Ғылыми мақалаларға талдау жасау барысындаметаболизмдіксиндромы бар адамдардың тамақтану тәртібі және өмір салты бұзылыстарының байланысы бар екендігі анықталды. Метаболизмдік синдромның (MС) анықтамасы оның әмбебап критерийлерін белгілеудегі қиындықтарға байланысты жылдар бойы бірнеше өзгерістерге ұшырады. Аталған синдроммен тығыз байланысты асқынулары жүрек-қан тамырлары аурулары және 2 типті қант диабеті болғантықтан,реттелетін факторлар ретінде тамақтану тәртібі мен өмір салтын модификациялау арқылы метаболиздік синдромы бар науқастарды жеке ерекшеліктерге бағытталған персонализацияланғантактика және асқынуларын алдын алу өзіндік септігін тигізеді.
ANALYSIS OF ANTIBIOTIC CONSUMPTION IN THE NATIONAL CENTER OF CHILDREN’S REHABILITATION FOR 2019- 2020 IN THE CONDITIONS OF THE COVID-19 PANDEMIC
Authors: Makalkina L.G. , Shakenov M.Zh. , Ihambaeva A.N. , Seikenova Zh.A. , Abdrakhmanova U.Sh. , Kusainova K.K. , Aldiyarova N.T.
Published: July 2024

The COVID-19 pandemic has posed a major challenge for all humanity and health systems in all countries. Excessive and unjustified use of antibiotics is one of the most important factors in the development of antibiotic resistance. Objective of the study: to identify the dynamics of antibiotic consumption in a children’s rehabilitation center during the COVID-19 pandemic for 2019-2020 and to identify factors affecting the incidence of infectious diseases and the consumption of antibiotics. Research methods: the calculation of antibiotic consumption was carried out according to the ATC / DDD methodology of the WHO Collaborating Center for Drug Statistics Methodology using the WHO database [4] to assign the ATC index and DDD values of drugs Results: The total consumption of antibacterial agents for systemic use (group J01) showed a decrease in DBD in 2020 compared to 2019 by 40% and amounted to 39.29 DBD in 2019 and 28.04 DBD in 2020. When assessing dynamic consumption antibiotics on arrival, we have identified a downward trend in antibiotic consumption after the introduction of strict quarantine measures at the Center. That, combined with data for 2020 on a decrease in the number of patients who were prescribed antibiotics and a decrease in the number of antibiotics per patient, showed the high effectiveness of restrictive measures at the Center related to the COVID-19 pandemic. Conclusions: the results of the study of antibiotic consumption for 2019-2020. according to the ATC / DDD methodology, it revealed an overall decrease in consumption in 2020 compared to 2019 by 40%, which is a positive result of the strict quarantine measures and an increase in the justification for prescribing antibiotics at the Center during the COVID-19 pandemic.
STRUCTURAL AND FUNCTIONAL CHANGES IN ANIMAL ORGANS UNDER THE ACTION OF THE COMPONENT «SILYBUM MARIANUM (L.) Gaertn.» IN OBESITY
Authors: Yessimsiitova Z.B. , Tileshova M.T. , Kozhamzharova A.S. , Yeltay G.Е. , Yestemirova G.A. , Yerkinbek U.Y. , Mombekov S.E.
Published: July 2024

To date, despite the huge success in the creation of synthetic drugs, a large number of medicinal preparations approved for use in scientific medicine include the active substances of higher plants. Medicinal plants are little studied and are a source for studying their use as a remedy. The use of any drug without knowledge of all its pharmacological effects is unacceptable. For modern medicine and pharmacy, the search for drugs with hepatoprotective activity still does not lose its relevance. This article presents information regarding the efficacy and safety of the use of silymarin in patients with acute toxic, including drug-induced, and chronic liver damage. In this regard, there is a need to study the currently available information on the composition, pharmacokinetics, mechanisms of action of Silybum marianum (L.) Gaertn., as well as its effectiveness in common diseases. The results of studies and systematic reviews of the use of silymarin in acute and chronic liver damage of toxic and infectious pathology indicate the high efficiency and safety of this drug in case of poisoning by toxic substances. At the same time, the question of the use of this plant as a dietary supplement remains not fully understood. At present, the dynamics of regeneration processes under physiological conditions, with injuries and various pathologies of tissues, has been quite fully studied and described. However, the regenerative processes at the cellular and subcellular level in obesity remain insufficiently studied, which makes it possible to describe in more detail the essence of regenerative processes, the ability to develop new methods for preserving the vital organ for the body, such as the liver and kidneys.
ШИНИРОВАНИЕ АКРОМИАЛЬНО-КЛЮЧИЧНОГО СУСТАВА ПРИ ЕГО ПОВРЕЖДЕНИЯХ (ОБЗОР ЛИТЕРАТУРЫ)
Authors: Молдакулов Ж.М. , Халходжаев М.К.
Published: July 2024

Лечение повреждений акромиально-ключичного сустава остается актуальной проблемой современной травматологии и ортопедии. В настоящее время для шинирование данного сустава специалисты широко используют различные импланты. Однако несмотря на известные преимущества, им присущи ряд недостатков. В этой связи перспективные исследования позволяют совершенствовать импланты для фиксации сустава при его повреждениях. Цель данной работы является изучение преимущества метода шинирования акромиально-ключичного сустава различными имплантами с использованием базы данных Scopus, PubMed, Google Scholar, Lilacs и Cuiden. Материалы и методы. В статье приведен анализ литературных источников, индексируемых в базах данных Scopus, PubMed, Google Scholar, Lilacs и Cuiden, посвященных исследованию метода шинирования акромиально-ключичного сустава различными имплантами. Результаты. В данном обзоре мы структурировали литературы, посвещенные для шинирования акромиальноключичного сустава, основываясь на их преимущаства и фиксационные свойства. Выводы. Анализ литературных источников, индексируемых в базах данных Scopus, PubMed, Google Scholar, Lilacs и Cuiden, посвящённые исследованию метода шинирования акромиально-ключичного сустава различными имплантами позволил установить как их приемущества, так и недостатки, а также необходимость проведения перспективных исследовании для дальнейшей оптимизации фиксационных свойств имплантов.
КӘДІМГІ ҮРКЕГҮЛ (FILIPENDULA VULGARIS М.) ЭКСТРАКТЫНЫҢ ХИМИЯЛЫҚ ҚҰРАМЫН ТАЛДАУ
Authors: ЖАНДАБАЕВА М.А. , ЖАҢАБАЙҚЫЗЫ С. , РАГАНИНА К.Т. , РЫСБЕК Ә.Ғ. , САРҚЫТБЕКОВА А.Қ.
Published: July 2024

Қазіргі таңда еліміздің фармацевтикалық нарығын дамыту мақсатында отандық өнімдердің сапасы мен санын арттыру жұмыстары үзіліссіз атқарылуда. Табиғи шикізат өнімдерінен, соның ішінде дәрілік өсімдік шикізаттарын фармацияда қолдану, қойылған міндеттерді атқарады. Соның бірі, кәдімгі үркегүл өсімдік шикізаты – ҚР таулы аймақтарында кеңінен таралған, халық медицинасында белгілі, көптеген фармакологиялық әсерге ие өсімдік. Мақалада ультрадыбыстық және құйынды экстракциялау әдістерімен алынған кәдімгі үркегүлдің (Filipendula vulgaris М.) қою экстрактысын алудың технологиялық параметрлері келтірілген; қою экстракттың компоненттік құрамы анықталған. Масс-спектрометриялық детекторы бар газ хроматографиясы әдісімен химиялық құрамына талдау барасынды ультрадыбыс экстракция әдісімен алынған экстракт құрамында фенолдық қосылыстардың пайыздық мөлшері (28 %) құйынды әдісімен алынған экстрактқа қарағанда жоғары болды (21 %). Фенолды қосылыстардың ең көп пайыздық мөлшері фенол (10,65%), гидрохинон (4,7%), 2-метоксифенол (1,41%), β-Dглюкопиранозид, метил (5,31%), салицил спирті (0,77%) ультрадыбысты экстракция әдісі арқылы алынған экстракттың құрамынан анықталды. Химиялық қосылыстардың фармакологиялық әсері анықталып, тиімді экстракция әдісі таңдап алынды. Нәтижелер осы өсімдікті ғылыми зерттеуге, жаңа дәрілік зат жасау үшін фенолды қосылыстардың мөлшері мен тиімді экстракты әдісін пайдалануға негіз болады.
РАСТЕНИЕ ПАРНОЛИСТНИК ОБЫКНОВЕННЫЙ (ZYGOPHYLLUM FABAGO L.) — КАК ИСТОЧНИК БИОЛОГИЧЕСКИ АКТИВНЫХ ВЕЩЕСТВ
Authors: Остемиркызы Д. , Капсалямова Э.Н. , Устенова Г.О. , Гемеджиева Н.Г. , Конаш Н.Е. , Жумабаев Н.Н.
Published: July 2024

Растение Парнолистник обыкновенный (Zygophyllum fabago L.), также известное как каперсы стручковые, является источником множества биологически активных веществ. В данном исследовании мы оцениваем его потенциал в качестве природного источника биологически активных соединений. В данном исследований проведен литературный обзор на растение парнолистника обыкновенного. В результате исследований обнаружены наличие различных классов биологически активных веществ, включая флавоноиды, фенольные соединения и сапонины. Исследователями изучены антиоксидантная активность парнолистника обыкновенного. В результатах исследований установлены, что парнолистник обыкновенный, обладает высокой антимикробной активностью, что может привести к потенциальным преимуществам для здоровья человека. Кроме того, растение было исследовано на наличие противогрибковой активности по отношению к грибам Candida albicans. Интересно отметить, что парнолистник обыкновенный, проявил хорошую противогрибковую активность, что может открыть новые перспективы для разработки лекарственных препаратов. Таким образом, исследование подтверждает, что парнолистник обыкновенный представляет собой перспективный источник биологически активных веществ, которые могут иметь потенциальные преимущества в различных областях медицины и фармакологии.
"Adapting Small-Scale Fiber Production to the 21st Century: Maine’s Evolving Strategies"
Authors: Welcomer Stephanie , Reynolds Mikayla
Published: July 2024

This study, funded by the US Small Business Administration, aims to better understand the operational, strategic, and economic dimensions of Maine’s fiber producers’ businesses. Fiber producers are those raising animal-based fiber, including sheep, alpacas, rabbits, and goats. The producer focus of this paper highlights the responses from the 27 fiber producers and their insights into the realities of Maine’s fiber sector.
The obesity treatment in adolescents inside their family environment
Authors: Olympia Smyrnioti  , Flora Bacopoulou  , Afroditi Zartaloudi  , Pantelis Perdikaris
Published: July 2024

Obesity in adolescence is emerging as a serious health problem since the rates of obese adolescents are rapidly increasing. In this important issue, the factors primarily responsible for obesity relate to the diet and physical fitness of young people, in addition to biochemical/genetic factors that contribute to the development of obesity. Incorrect dietary choices and, in general, the adoption of an unhealthy lifestyle start very early, with the family playing a pivotal role. The already high number of obese adolescents has a negative impact on their lives and society in general. One category of measures/interventions that could be taken to prevent childhood obesity is related to the family environment. Therefore, this thesis will study the existing literature in order to understand what obesity is, the factors that contribute to its occurrence and the ways in which the family can influence the behavior of adolescents and be a means of treating obesity (behavior, diet, physical activity, sleep, etc.). A review of the literature was conducted, using authoritative health databases (PubMed and Scopus), to identify published articles on family interventions that contribute to the treatment of adolescent obesity. The systematic review showed that the family holds considerable influence over its members, which, when dysfunctional, can lead to the acquisition of excess weight in its members. Intervention programs within the family environment showed a positive effect on weight loss in adolescents. The involvement of all the family members in these programs (parents and teenagers), not just teenagers, had even more positive results. Intervention programs targeting the family are able to change the daily habits of family members, resulting in adolescents acquiring healthy eating habits and increasing their physical activity, leading to the loss and/or maintenance of normal weight.
Assessment of the effects of physiological development of cocoa (Theobroma cacao l.) explant on somatic embryogenesis
Authors: Folasade Elisbeth Mapayi  , Adenike Anne Muyiwa  , Olutayo Olalekan Adenuga  , Olayinka Olufemi Olaniyi  , Funlayo Abigail Adepoju  , Chinyere Florence Odey
Published: July 2024

Cocoa trees have shown a high degree of segregation for many traits when propagated by seeds. Somatic embryogenesis is an efficient in vitro propagation method which allows the production of several embryos capable of generating plants similar to the initial one from somatic tissues. The use of cocoa floral parts has been reported for regeneration of elite cocoa genotypes. This research is targeted in evaluating the effect of physiological development of the explants (staminode) and its response to two different cytokinase (kinetin and BAP) on embryogenesis. The experiment was laid in factorials with three replications in CRD. Three different physiological ages of the explant were examined: 1 week old (unopened, about 3-4 mm in length),2 weeks old (unopened, about 5-/6 mm in length) and 3 weeks old (unopened; matured flowers). Staminode was studied and explants were initiated for callus induction on Primary Callus Growth medium. The following data were scored for: Explants Induction Percentage, Percentage of callus induced and Percentage of Embryogenic callus. Results showed the interactions among the genotypes, hormones and the physiological age of the explants were significantly different at 0.05% probability level. Explants at 3 and 2 weeks respectively had higher efficiency for embryogenesis while the average performance was observed for explants at a week. Also, BAP recorded higher frequency 80% for embryogenesis compared to kinetin 70% under the present study. Physiological age of explants and the choice of callus development hormone have been found to play significant role in the embryogenesis of cocoa genotypes examined.
FEASIBILITY AND OUTCOMES OF DELAYED CORD CLAMPING IN PRETERM NEWBORNS
Authors: ZIA N , WASIMULLAH . , NAZIR S , TOFAIL S
Published: July 2024

babies, and it offers higher chances of the survival of preterm infants. Objectives: The study aims to find the feasibility and outcomes of delayed cord clamping in preterm infants. Methods: This prospective observational study was conducted at Indus Hospital Karachi from January 2023 to December 2023. Data include 180 pre-term infants in the study. The study consisted of preterm infants born at gestational ages ranging from 28 to 34 weeks, admitted to the NICU within the first 24 hours of life. Infants with no congenital anomalies or significant perinatal complications requiring immediate medical intervention were included in the study. Clinical and demographic data were collected prospectively from medical records and direct observations. Results: Data were collected from 180 preterm infants. The mean gestational age in the DCC group was 31.01±2.00 weeks, and in the ICC group was 31.89± 1.78 weeks. Mean birth weight was 1500±300g and 1500±200g in the DCC and ICC groups, respectively. The mean maternal age was 28.09±4.1 years in DCC and 28.01±4.34 years in the ICC group. In the study, delayed cord clamping (DCC) demonstrated a high feasibility level, with 85% adherence to the DCC protocol among the 90 enrolled infants. Most infants adhered to the recommended duration, with a mean clamping time of 45 seconds, falling within the target range of 30 to 60 seconds. Conclusion: It is concluded that delayed cord clamping (DCC) appears feasible and offers potential benefits in improving short-term outcomes for preterm infants in the neonatal intensive care unit (NICU).