bluuebunny/crossref_metadata_2025 huggingface dataset:
SPECIES COMPOSITION OF PHYTOPLANKTON OF THE BLAGODATNOYE LAKE (ITURUP ISLAND, KURIL ISLANDS, RUSSIA)
Authors:   Federal Scientific Center of the East Asia Terrestrial Biodiversity, Far East Branch of the Russian Academy of Sciences, Vladivostok, 690022, Russia, Nikulina T.V. , Motylkova I.V. ,   Sakhalin Branch of “Russian Federal Research Institute of Fisheries and Oceanography” (SakhNIRO), 196 Komsomolskaya Street, Yuzhno- Sakhalinsk, 693023, Russia
Published: June 2023

Algological studies conducted in June–August 2021 on the lagoon Blagodatnoye Lake (Iturup Island) and showed a high diversity of species composition of cyanobacteria and algae (274 species and intraspecifi c taxa from eight divisions: Cyanobacteria, Miozoa, Bacillariophyta, Chlorophyta, Charophyta, Criptista, Ochrophyta, Euglenozoa). Diatoms make up a signifi cant share in the formation of algofl ora (73,2 % of the total number of species). Complexes of dominant species in lake plankton are represented by cyanobacteria and diatoms: Aulacoseira granulata and it’s variation A. granulata var. angustissima Aphanizomenon fl os-aquae (August). The maximum values of quantitative indicators of the main dominants reached: N = 1323,3 thousand cells/l, B = 685,5 mg/l for Asterionella formosa, and N = 3646 thousand cells/l, B = 4579,4 mg/l for Aulacoseira granulata. The ecological and geographical characteristics of the algal fl ora of Blagodatnoe Lake were carried out: benthic species (48,2 % of the total number of taxa), indiff erent to salinity change (68,6 %), alkaliphilic (42,3 %), cosmopolitan (70,1 %) species were predominance, and oligosaprobionts and betamesosaprobionts were 35,4 and 33,9 %, respectively.
TAXONOMIC SIGNIFICANCE OF MORPHOLOGICAL CHARACTERS OF DIAMESA TSUTSUII TOKUNAGA (DIPTERA, CHIRONOMIDAE, DIAMESINAE)
Authors:   Federal Scientific Center of the East Asia Terrestrial Biodiversity, Far East Branch of the Russian Academy of Sciences, Vladivostok, 690022, Russia, Sayenko E.M. , Makarchenko E.A. ,   Federal Scientific Center of the East Asia Terrestrial Biodiversity, Far Eastern Branch of the Russian Academy of Sciences, Vladivostok 690022, Russia
Published: June 2023

Collection of larvae and male imago of Diamesa tsutsuii (Tokunaga, 1936) (Diamesinae, Chironomidae, Diptera) from a few localities of Sakhalin Island and Primorye stored in the Laboratory of Freshwater Hydrobiology FSCEATB FEB RAS (Vladivostok) is under discussion. A comparison of conchological features with the purpose to check the validity of taxonomic characters is made.
THE MAYFLIES (INSECTA, EPHEMEROPTERA) OF THE NORTH OF THE FAR EAST OF RUSSIA
Authors:   Federal Scientific Center of the East Asia Terrestrial Biodiversity, Far East Branch of the Russian Academy of Sciences, Vladivostok, 690022, Russia, Khamenkova E.V. ,   Institute of Biological Problems of the North FEB RAS, 18 Portovaya St., Magadan,685000, Russia
Published: June 2023

Based on the literature and original data, a review of the fauna of mayflies (Ephemeroptera) of the North of the Russian Far East is given. To date, the faunistic list of mayfl ies in the region includes 72 species from 23 genera and 8 families. In the watercourses of the Magadan Region, 52 species are recorded, Chukotka Autonomous District – 27, the north of the Khabarovsk territory (a part of Okhotsk north of the Tugur River in the south and the Okhota River in the north) – 57, and Kamchatka – 37 species. Within local faunas, species with the Eastern Palearctic type of distribution prevail in all regions of the North of the Far East, reaching a maximum in north of the Khabarovsk Territory (54 %). The species richness of mayfl ies revealed for the North of the Far East is much less than in the watercourses and reservoirs of the south of the Far East and Eastern Siberia (bass of Lake Baikal), but quite comparable with the fauna of adjacent territories and other northern European countries.
Óbitos por Beribéri no Brasil, 1996 a 2020
Authors: Santos João Vitor de Oliveira Fernandes , Branco Maria dos Remédios Freitas Carvalho , Maximino Flávio Donalwan Sá , Santos Thiago de Sousa , Dias Júnior José de Jesus , Soeiro Vanessa Moreira da Silva , Frota Maria Tereza Borges Araújo , Oliveira Bruno Luciano Carneiro Alves de , Santos Alcione Miranda dos , Padilha Estela Maura
Published: June 2023

Objetivo: Descrever os óbitos por beribéri no Brasil de 1996 a 2020. Métodos: Estudo descritivo dos óbitos por beribéri no país, registrados no Sistema de Informação sobre Mortalidade (SIM), de 1996 a 2020. Resultados: Encontrou-se 352 óbitos por beribéri no SIM, tendo sido excluídos dois registros devido à ausência de informação do município de residência. Houve registro de óbitos em 25 unidades federativas (UF), com predomínio em São Paulo (72; 20,6%), Minas Gerais (54; 15,4%) e Rio Grande do Sul (40; 11,4%). Foram registrados ao menos um óbito em 241 (4,3%) municípios com maior frequência em São Paulo (20; 5,7%), Salvador (16; 4,5%), Belo Horizonte (13; 3,7%), Imperatriz (13; 3,7%), Rio de Janeiro (12; 3,4%) e Porto Alegre (12; 3,4%). Conclusão: Os registros demonstram que o beribéri ocorre a nível nacional e deveria ser, portanto, incluído como doença de notificação compulsória, evitando a subnotificação e o sub-registro. Observou-se um aumento no registro de óbitos entre 2017 e 2020, em virtude da crise econômica e do crescimento da fome e da pobreza, acentuada pela pandemia da COVID-19.
Propriedades terapêuticas das plantas medicinais nas doenças cardiovasculares
Authors: Baratieri Jamili Laís , Badke Marcio Rossato , Mendes Nathália Bordin , Oliveira Gabriela , Cordeiro Pedro Henrique , Cogo Silvana Bastos , Schimith Maria Denise
Published: June 2023

Objetivo: analisar as evidências científicas acerca das plantas medicinais que possuem propriedades terapêuticas em patologias que acometem o sistema cardiovascular. Métodos: revisão integrativa de literatura realizada nas bases de dados MEDLINE e LILACS via BVS e MTCI nas Américas, com artigos publicados entre 2000 e janeiro de 2023. Foram utilizados os descritores controlados “plantas medicinais” AND “doenças cardiovasculares” e encontrados 406 estudos. Após aplicado os critérios de exclusão e inclusão, o corpus final é composto por nove estudos. Resultados: as seguintes plantas foram sinalizadas benéficas para doenças cardiovasculares: Nelumbo nucifera Gaertn, Citrus aurantifolia, Rhammus alaternus, Centaurium erythrea. As evidências apontaram para efeitos cardioprotetores sobre o diabetes, dislipidemia, hipertensão e obesidade. As plantas mais citadas para o tratamento de dislipidemia foram o Zingiber officinale, Allium sativum e Cynara cardunculus var. scolymus, para o diabetes o Cuminum Cyminum, para a hipertensão a Macrotyloma uniflorum Verdc, Hibiscus sabdariffa e Citrus limon, e para a obesidade a Azadirachta indica A. Jus.  Considerações finais: os estudos demonstraram evidências científicas favoráveis a partir de extratos de plantas medicinais, bem como, para a formulação de novas drogas. Portanto, há necessidade de novos estudos que explorem os potenciais terapêuticos das plantas medicinais na sua forma in natura.
Innover dans l'enseignement de la natation
Authors: Fayaubost Régis , Roche Lionel , Rolland Cathy , Maire Sébastien
Published: June 2023

Notre contribution rend compte d’une innovation développée dans le cadre de l’enseignement de la natation en EPS. En effet, afin de lutter contre les appréhensions relatives au milieu aquatique qui peuvent constituer un frein à l’acquisition du savoir-nager, nous avons développé une approche reposant sur trois étapes : 1) douche et contenants, 2) outils pour le ciblage des phobogènes et 3) masques de réalité virtuelle (RV) et vidéo 360°. La principale innovation de la démarche d’enseignement que nous présentons ici repose sur une entrée par la sphère émotionnelle et le recours à des vidéos 360° tournées sous l’eau et visionnées par les élèves grâce à un casque de réalité virtuelle. A l’issue de cette démarche, les élèves ressentent une appréhension moins élevée. Ils ont aussi pu acquérir les premiers indices perceptifs sous l’eau et des connaissances liées à l'environnement aquatique.
Principled blended learning materials for language acquisition
Authors: Tomlinson Brian
Published: June 2023

(Invited Expert Article) This paper focuses on how the development of principled blended learning materials can facilitate the acquisition of an L2. By materials development I mean the design, production, and utilisation of anything intended to facilitate language acquisition. This could be a story, a listening activity, a debate, a photo, a video, a board game, a communication task, a blog, a discovery task, an advertisement, an e-mail or even a sequence of questions. By principled I mean informed by what we know from research and observation about what best facilitates language acquisition. By blended learning I mean learning which makes use of both face to face and a distance modes to facilitate language acquisition. And by the acquisition of an L2 I mean the gradual development of the ability to communicate effectively in a second or foreign language. To help learners achieve language acquisition I am advocating the principled design and use of blended learning materials. I am also specifying what I think are the four most important principles of language acquisition and for each one deriving and exemplifying principles and procedures of materials development.
STRUKTUR ANATOMI DAN SIFAT FISIK KAYU JATI (Tectona grandis L.f.) UNGGUL NUSANTARA TRUBUSAN PADA UMUR 8 TAHUN
Authors: Susdiyanti Tun , Meiganati Kustin Bintani , Lidiawati Ina , Abiksak Angraini
Published: June 2023

Teak (Tectona grandis L.f.) Unggul Nusantara is a superior seed yield and tissue culture propagation that was first developed in the laboratory and a good quality mother plant. This research aims to find out the characteristic of Anatomical Structure and Physical Properties of Jati Wood (Tectona grandis L.f.) Unggul Nusantara Copies at the age of 8 years. The study was carried out for approximately 6 months between May and October 2021. Anatomical structure data collection was made of triangle shape with latitude, tangential, and radial. Afterwards, the result of these observations are tabulated and analyzed descriptively and the Physical Properties of Copies Jati Unggul Nusantara Wood were carried out with reference to on British Standard (BS) 373:1957. It taken from one tree and then divided again into three segments, the tip, middle, and base with a thickness of 20 cm. Afterwards, divided again into five parts with a size of 3 cm x 3 cm x 3 cm for 3 parameters. Observations of anatomical structures, namely pore or vessel diameter 100-200 m, vessel frequency or pores 6 per mm2, the width of the radius is 96m and the frequency of the radius is 4-5 pieces / mm. Its physical properties are Fresh Water Content 52.30% while Air Dry Water Content 32.69%, Density 1.20 gr/cm3, Tangential Shrinkage 0.44%, Radial Shrinkage 0.42%, with an average T/R ratio 1.04%.Keywords: Anatomical Structure, Copies Wood, Physical Properties, Tectona grandis L.f.AbstrakJati (Tectona grandis L.f.) Unggul Nusantara merupakan bibit unggul hasil dan perbanyakan kultur jaringan yang dikembangkan pertama kali di Laboratorium dan tanaman induk yang berkualitas baik. Penelitian ini dilaksanakan di Laboratorium Universitas Nusa Bangsa, Bogor dan Pusat Standardisasi Instrumen Pengelolaan Hutan Berkelanjutan Gunung Batu, Bogor. Penelitian dilaksanakan selama kurang lebih 6 bulan antara bulan Mei sampai bulan Oktober 2021. Pengambilan data Struktur Anatomi dibuat dalam bentuk segitiga dengan bagian Lintang, Tangensial dan Radial lalu hasil pengamatan ditabulasi dan dianalisis secara deskriptif, dan Sifat Fisik Kayu Trubusan Jati Unggul Nusantara dilakukan dengan mengacu pada British Standard 373:1957. Diambil dari 1 pohon kedalam tiga segmen ujung, tengah, dan pangkal dengan ketebalan 20 cm, kemudian menjadi lima bagian dengan ukuran 3 cm x 3 cm x 3 cm untuk 3 parameter dan diberikan 3x ulangan untuk 3 parameter. Hasil pengamatan Struktur Anatomi yaitu Diameter pori atau pembuluh 100 – 200 μm, Frekuensi pembuluh atau pori 6 per mm2, Lebar jari – jari 96 μm dan Frekuensi jari – jari berjumlah 4 – 5 buah/mm. Sifat Fisiknya yaitu Kadar Air Segar 52,30 % sedangkan Kadar Air Kering udara 32,69 %, Kerapatan 1,20 gr/cm3, Penyusutan Tangensial 0,44 %, Penyusutan Radial 0,42 %, dengan rata – rata T/R rasio 1,04 %. Kata kunci: Struktur Anatomi, Kayu Trubusan, Sifat Fisik, Tectona grandis L.f
PEMANFAATAN TUMBUHAN DALAM ACARA ADAT OLEH MASYARAKAT SUKU GAYO DI DESA PENOSAN SEPAKAT KECAMATAN BLANGJERANGO KABUPATEN GAYO LUES, ACEH
Authors: Handayani Triaty , Ridwan Ridwan
Published: June 2023

Masyarakat suku gayo memiliki hubungan erat dengan alam dan lingkungan. Masyarakat memanfaatkan berbagai tumbuhan yang ada di sekitar dalam tradisi adat yang telah turun temurun dari para leluhur. Penelitian ini bertujuan untuk mengetahui spesies tumbuhan yang dimanfaatkan oleh masyarakat dalam upacara adat serta menjadi sumber tertulis bagi masyarakat terutama para generasi. Pengumpulan data dilakukan dengan survei lapangan, dokumentasi dan wawancara mendalam (in deft interview) dengan para tokoh adat, tokoh agama, tokoh orang tua dan tokoh masyarakat. Masyarakat mengenal tumbuhan adat yang digunakan dengan Dun kayu kul dan Dun kayu ucak, yang terdiri dari beberapa spesies tumbuhan dan beberapa upacara adat yang memiliki makna yang dipercaya oleh masyarakat suku Gayo. Jenis tumbuhan adat yang dimanfaatkan tidak bisa digantikan dengan jenis tumbuhan lain karena akan menghilangkan makna dan kesakralan pelaksanaan upacara adat.
Protonation Process of Porous Silica Cluster Surface using Molecular Dynamics Method
Authors: Alfaridzi Raihan , Nugroho Bintoro Siswo , Rosandi Yudi
Published: June 2023

Using molecular dynamic simulation, we developed an algorithm to protonate the surface of an amorphous porous silica grain particle model and study its effect. In this work, the silica grain model can be used to study cosmic dust coagulation. The surface of the silica cluster was protonated by placing H atoms on oxygen atoms having only a single bond, namely, the non-bridging oxygens. The H atoms are placed opposite the Si–O bond with a distance of around 1 Å to form silanol (Si–O–H) group termination on the silica surface. The angular conformation of the silanol was optimized by relaxing the surface at low temperature. We evaluated the number of silanol groups, the angular distribution of the Si-O-H bond, and the average distance between Si-O particles using the radial distribution function (RDF). The result of the study shows that minimizing the energy of the silica surface changes the angular distribution of the silanol from 180° to about 110° and between 140°-160°. However, the average distance between Si-O particles remains at 1 Å, which demonstrates the correctness of the atomic interaction model. The addition of protons on the silica surface is an essential factor in the simulation of cosmic dust collision since the modification of the surface chemistry may alter the contact surface energy, thus changing the probability of particle coagulation.
Melt and Solution Processability of PBS-DLS Copolymers Modified with PEG using 3D Printing and Electrospinning
Authors: Zarei Moein , Żwir Marek J. , Wiśniewska Ewa , Michalkiewicz Beata , El Fray Miroslawa
Published: June 2023

Fabrication of complex structures usually requires a combination of different advanced manufacturing techniques at different length scales. In this work, we discuss the structure-properties relationship of recently developed biodegradable poly(butylene succinate-dilinoleic succinate) (PBS-DLS) copolymers modified with hydrophilic poly(ethylene glycol) (PEG) towards their processibility via 3D printing and electrospinning. Notably, filaments suitable for 3D printing with 1.75mm in diameter were fabricated directly from the reactor after the synthesis of copolymers through extruding polymer melt into a water bath thus overcoming the post-processing. Two series of copolymers containing 60 wt% and 70 wt% of hard PBS content were synthesized using magnesium-titanium butoxide as heterometallic catalyst. Differential scanning calorimetry indicated biphasic morphology with low glass transition temperature and high melting point, which were dependent from the PBS hard segments content. Crystallized copolymers exhibited distinct spherulitic morphology, but presence of crystallites has no adverse effect on warping or delamination of subsequent layers during 3D printing. Furthermore, these copolymers demonstrated also easy processability through electrospinning, yielding uniform nanofibers with diameters ranging from 400 to 600 nm. The addition of 5 wt% PEG to copolymers with higher hard segments content (70 wt%) increased the elasticity up to 830% and improved hydrophilicity of the copolymers. Overall, these findings together with the excellent cell viability of new materials highlight their potential for different applications, including biomedical sector.
Lethal weapon IL: a nano-copper/tetraalkylphosphonium ionic liq-uid composite material with potent antibacterial activity
Authors: Banerjee Abhinandan , Aremu Bukola R. , Dehghandokht Sima , Salama Rayan , Zhou Hao , Lackie Sharon , Seifi Moutasem , Kennepohl Pierre , Trant John
Published: June 2023

Ionic liquid (IL) based composite materials have shown great promise as antimicrobial coatings, owing to their inherent germicidal properties, as well as their ability to stabilize metal nanoparticles (NPs), which may serve as a secondary antimicrobial reservoir. Here, we show that tetraalkylphosphonium ILs (TAPILs) on their own can annihilate pathogens by interfering with their cell membranes; however, the nature of the alkyl substituents on the central P atom and the nature of the anion play decisive roles in determining their antimicrobial activities. Con-comitantly, TAPILs can stabilize copper nanoparticles (Cu NPs) generated directly within the IL matrices without the addition of any second-ary stabilizers. The composites thus generated were thoroughly characterized and shown to be far more lethal to E. coli than just the TAPILs. The antibacterial effect demonstrated by the composite created from P[6,6,6,8]Cl (TAPIL-2) was orders of magnitude more lethal to microbes in comparison with P[6,6,6,8]Cl or copper nanoparticles alone. Neither the parent TAPIL-2 nor composite-2 were compromised by ambient storage conditions over a period of months with regards to their bactericidal effects. The composite with the best performance (composite-2) also proved to be effective against a panel of selected microbes. SEM studies were conducted to image E. coli after exposure to the TAPILs or composite-2; with the latter, only bacterial debris were noticed post-exposure, indicating total bacterial annihilation. The killing kinetic assay and regression analyses for time-dependent bactericidal activity of composite-2 against E. coli and S. aureus demonstrated increase in log re-duction values over time, indicating the effectiveness of composite-2 in reducing the viable cell counts for both bacterial strains. Finally, Cu K-edge XANES was used to investigate the fate of Cu NPs within the composites, revealing oxidative disintegration of the Cu NPs within the TAPIL matrices over time, releasing charged copper ions and/or small copper clusters which interfere with the integrity and the permeability of E. coli cell membranes, inducing cell death. This was confirmed by SEM of bacterial preparations before and after exposure to both the TAPILs themselves as well as to the composites. Exposing E. coli to composite-2 causes complete cellular destruction, leaving behind cellular debris as the only visible organic matter. Thus, these TAPIL-based composites containing ‘ion reservoir’ metal NPs are potent antimicrobial materials, deserving additional research.
Open Source Antibiotics - Simple Diarylimidazoles are Potent Against Methicillin Resistant Staphylococcus Aureus
Authors: Klug Dana , Tse Edwin , Silva Daniel , Cao Yafeng , Charman Susan , Chauhan Jyoti , Crighton Elly , Dichiara Maria , Drake Chris , Drewry David , Emery Flavio , Ferrins Lori , Graves Lee , Hopkins Emily , Kresina Thomas , Lorente-Macias Alvaro , Perry Ben , Phipps Richard , Quiroga Bruno , Quotadamo Antonio , Sabatino Giada , Sama Anthony , Schaetzlein Andreas , Simpson Quillon , Steele Jonathan , Shanu-Wilson Julia , Sjö Peter , Stapleton Paul , Swain Chris , Vaideanu Alexandra , Xie Huanxu , Zuercher William , Todd Matthew
Published: June 2023

Antimicrobial resistance (AMR) is widely acknowledged as one of the most serious public health threats facing the world, yet the private sector finds it challenging to generate much-needed medicines. As an alternative discovery approach, a small array of diarylimidazoles was screened against the ESKAPE pathogens (https://en.wikipedia.org/wiki/ESKAPE) and the results made publicly available through the Open Source Antibiotics (OSA) consortium (https://github.com/opensourceantibiotics). Of the 18 compounds tested (at 32 μg/mL), 15 showed >90% growth inhibition activity against MRSA alone. In the subsequent hit-to-lead optimization of this chemotype, 147 new heterocyclic compounds containing the diarylimidazole and other core motifs were synthesized, tested against MRSA and structure-activity relationships identified. While potent, these compounds have moderate to high intrinsic clearance and some associated toxicity. The best overall balance of parameters was found with OSA_975, a compound with good potency, solubility and reduced intrinsic clearance in rat hepatocytes. We have progressed towards the knowledge of the molecular target of these phenotypically active compounds, with proteomic techniques suggesting TGFRB1 is potentially involved in the mechanism of action. Further development of these compounds towards antimicrobial medicines is available to anyone under the licensing terms of the project.
FASTDock: A Pipeline for Allosteric Drug Discovery
Authors: Ahmed Furyal , Brooks Charles
Published: June 2023

Allostery is involved in innumerable biological processes and plays a fundamental role in human disease. Thus, exploration of allosteric modulation is crucial for research on biological mechanisms and in the development of novel therapeutics. Development of small molecule allosteric effectors can be used as tools to probe biological mechanisms of interest. One of the main limitations in targeting allosteric sites, however, is the difficulty in uncovering them for specific receptors. Furthermore, upon discovery of novel allosteric modulation, early lead generation is made more difficult as compared to orthosteric sites, because there is likely no information about the types of molecules that can bind at the site. In the work described here, we present a novel drug discovery pipeline, FASTDock, which allows one to uncover ligandable sites, as well as small-molecules that target the given site, without requiring pre-existing knowledge of ligands that can bind in the targeted site. By using a hierarchical screening strategy, this method has the potential to enable high throughput screens of an exceptionally large database of targeted ligand space.
Electronic structures of nickel(II)-bis(indanyloxazoline)-dihalide catalysts: Understanding ligand field contributions that promote C(sp2)–C(sp3) cross-coupling
Authors: McNicholas Brendon , Tong Z. Jaron , Bím Daniel , Turro Raymond , Kazmierczak Nathanael , Chalupský Jakub , Reisman Sarah , Hadt Ryan
Published: June 2023

NiII(IB) dihalide [IB = (3aR,3a'R,8aS,8a'S)-2,2'-(cyclopropane-1,1-diyl)bis(3a,8a-dihydro-8H-indeno[1,2-d]-oxazole)] complexes are representative of a growing class of first-row transition metal catalysts for the enantioselective reductive cross-coupling of C(sp2) and C(sp3) electrophiles. Recent mechanistic studies highlight the complexity of these ground state cross-couplings, but also illuminate new reactivity pathways stemming from one-electron redox and their significant sensitivities to reaction conditions. For the first time, a diverse array of spectroscopic methods coupled to electrochemistry has been applied to NiII-based pre-catalysts to evaluate specific ligand field effects governing key Ni-based redox potentials. We also experimentally demonstrate DMA solvent coordination to catalytically-relevant Ni complexes. Coordination is shown to favorably influence key redox-based reaction steps and prevent other deleterious Ni-based equilibria. Combined with electronic structure calculations, we further provide a direct correlation between reaction intermediate frontier molecular orbital energies and cross-coupling yields. Considerations developed herein demonstrate the use of synergic spectroscopic and electrochemical methods to provide concepts for catalyst ligand design and rationalization of reaction condition optimization.
Exploring Propane/Propylene Separation through Molecular Dynamics Simulations of Flexible Metal-Organic Framework Models
Authors: Suyetin Mikhail
Published: June 2023

Propylene is a vital component for the petrochemical industry. The overwhelming majority of the studies is focused on propylene/propane separation. Nevertheless, as the ultimate goal is to obtain propylene as the end product, propylene-selective MOFs necessitate a demanding and complex desorption process, which consumes a substantial amount of energy and involves intricate operations. Consequently, having an adsorbent that preferentially adsorbs propane instead would be more advantageous. This approach would enable the production of high-purity propylene in a single step and lead to significant reductions in energy consumption and the quantity of adsorbent required. The Computation-Ready Experimental Metal-Organic Framework (CoRE MOF) 2019 database is utilized for the computational screening of flexible MOFs using molecular dynamics simulations to identify materials with strong potential for separating propane/propylene via self-diffusion. This screening process is the first to fully consider the impact of framework flexibility on the discovery of guest self-diffusion coefficients. The study underscores the significance of accounting for framework flexibility in investigations of gas molecules transport in MOFs, showcases the potential of using data-driven approaches to identify high-performance materials, and suggests methods for enhancing the predictive capabilities of screening workflows. The top 5 MOFs from the CoRE MOF database for propane and propylene separation at a temperature of 298 K are identified. It is observed that the presence of carbonyl groups greatly enhances the separation properties between propane and propylene. Subsequently, a machine learning approach is utilized to develop a model and uncover important features. The machine learning model's predicted values for self-diffusion are reasonably consistent with the data obtained from molecular dynamics simulations.
Unlocking Tertiary Acids for Metallaphotoredox C(sp2)-C(sp3) Decarboxylative Cross-Couplings
Authors: Guo Junqing , Norris Derek , Ramirez Antonio , Sloane Jack L. , Simmons Eric M. , Ganley Jacob M. , Oderinde Martins S. , Dhar T. G. Murali , Davies Geraint H. M. , Sherwood Trevor C.
Published: June 2023

Dual nickel photoredox catalysis conditions have been developed for the decarboxylative cross-coupling of aryl halides and carboxylic acids containing fully substituted alpha carbons, a valuable but challenging substrate class for C(sp2)–C(sp3) bond-forming reactions. High-throughput experimentation identified Ni(TMHD)2 as the optimal precatalyst for this reaction in contrast to the nickel-bipyridyl complexes typically employed in decarboxylative couplings, which predominantly furnished undesired C–O products. Computational work provides insight into the potential mechanistic underpinnings for the C–C vs. C–O selectivity for the nickel-diketonate complex.
High-Throughput Automated Exploration of Phase Growth Behaviors in Quasi-2D Formamidinium Metal Halide Perovskites
Authors: Yang Jonghee , Lawrie Benjamin J. , Kalinin Sergei V. , Ahmadi Mahshid
Published: June 2023

Quasi-two-dimensional (2D) metal halide perovskites (MHPs) are an emerging material platform for sustainable functional optoelectronics, however the uncontrollable, broad phase distribution remains a critical challenge for applications. This is because the basic principles for controlling multiple phases in quasi-2D MHPs remain poorly understood, due to the rapid crystallization kinetics during the conventional thin-film fabrication process. Herein, a high-throughput automated synthesis-characterization-analysis workflow is implemented to accelerate material exploration in formamidinium (FA)-based quasi-2D MHP compositional space, revealing the early-stage phase growth kinetics which fundamentally determines the phase distributions. We observe that the prominent n=2 2D phase restricts the growth kinetics of 3D-like phases – α-FAPbI3 MHPs where the spacers are coordinated to the surface. δ-FAPbI3 phase further inhibits the growth of 3D-like phases. It is found that thermal annealing is a critical step for proper phase growth, although it can lead to the emergence of unwanted local PbI2 crystallites. Additionally, fundamental insights into the precursor chemistry associated with spacer-solvent interaction that determines the morphologies and microstructures of quasi-2D MHP films are demonstrated. Our high-throughput study provides comprehensive insights into the fundamental principles in quasi-2D MHP phase control and enables new control of the functionalities of complex materials systems for sustainable device applications.
Los 5 pilares del análisis económico del derecho en la era post COVID
Authors: Martín Coronado José Manuel
Published: June 2023

El presente artículo propone 5 pilares necesarios para hacer un real Análisis Económico del Derecho — AED: la narrativa jurídico-económica, los diagramas de causalidad, las ecuaciones matemáticas, los gráficos en planos cartesianos y el uso y/o análisis de datos. Mientras que muchos abogados se resisten en reconocer la importancia de estos 5 pilares, los economistas se separan entre quienes los usan total o parcialmente y quienes no. El enfoque cuantitativo es el corazón de todo análisis económico, y el AED no es la excepción.
Una mirada a la identificación de las competencias directivas
Authors: Hernández Magaña Jacqueline , Padilla Aguilar Daimeé , Piñero Rodríguez Narciso Abel
Published: June 2023

La investigación que se presenta tuvo como objetivo identificar las competencias directivas aplicando el modelo de evaluación de desempeño en empresas de alta tecnología. Este modelo se basa en un estudio cuantitativo y cualitativo. El método cualitativo permite profundizar en la percepción de los trabajadores y su valoración sobre la gestión de dirección en la empresa. En cuanto al método cuantitativo, este contribuye al análisis de los datos derivado de las herramientas empleadas, respaldadas por el resultado del desempeño anual de los directivos, encuestas a los trabajadores a las que se les aplica la clasificación de las competencias directivas de los expertos, y encuestas sobre la calidad directiva a ambos segmentos, directivos y trabajadores. Los resultados muestran una proporción entre las tres competencias directivas: las estratégicas, las internas de la organización y las de eficacia personal; tienen prevalencia las competencias estratégicas.
Análisis del desempeño de la red de agua potable en Salina Cruz, México
Authors: Ponce Martínez Adriana Eneida , Martínez Mendoza Eduardo , Ríos Esperanza Rafael
Published: June 2023

El objetivo del presente trabajo fue evaluar el desempeño de una red de distribución de agua potable. Los datos se obtuvieron por medio del personal del sistema de aguas del municipio en estudio. Se emplearon métricas de capacidad Six Sigma para evaluar su desempeño mediante la simulación con el software EPANET. De acuerdo con los resultados, el sistema estudiado no cumple con los requerimientos de los usuarios. El desabastecimiento de agua no se debe a la falta de extracción, sino a las pérdidas que ocurren en el sistema, que pueden alcanzar hasta el 43 %. Se comparó el desempeño actual con el obtenido al inducir cambio en la simulación. El desempeño de la red puede ser mejorado con cambios en algunas condiciones de bombeo, distribución; además, la red requiere revisión y mantenimiento para evitar la pérdida de agua. Incrementar la extracción ocultaría el problema de desperdicio y generaría sobreexplotación de los pozos.
Business ecosystems for sustainability: why and how firms and public partners share ecosystem leadership?
Authors:   Grenoble Ecole de Management, Vernay Anne-Lorène , Sebi Carine , Moratal-Ferrando Nuria ,   Nantes Université
Published: June 2023

Systemic innovation that aims to tackle complex societal problems require multiple actors to coordinate their efforts and materialize through business ecosystems for sustainability (BMfS). BMfS aim to combine both market and environmental logics. We discuss what their distinctive characteristics and analyze how they influence the difficulties ecosystem leader encounter to be able to manage ecosystem coordination problems. This paper aims to discuss the importance of public actors in helping overcoming these coordination challenges by helping access bottleneck resources. It identifies a number of roles public actors can play and discusses the need to implement a hybrid leadership between public and private actors to enable the emergence and growth of business ecosystems for sustainability.
Alternative Design Theories and the Temporal Nature of Top-Down Entrepreneurial Ecosystem Support Processes: Implications for Resource-Constrained Emerging Ecosystems in Transition
Authors:   University of London, Schiller Victor
Published: June 2023

Entrepreneurial Ecosystem (EE) research has explored bottom-up ecosystems that spontaneously appear then develop over time and top-down formed ecosystems deliberately established through organizational sponsorship designed to enable productive entrepreneurship. Despite the crucial role organizational sponsorship plays in entrepreneurial support activities, prior research has overlooked the critical design methods used to formulate the strategy and temporal dynamic factors required to establish and operate top-down emerging resource-constrained ecosystems. Specifically, in the year leading up to initial ecosystem launch, which design methods are used to determine entrepreneur support activities and timing, then what is modified during the first year of operation? Approaching top-down established ecosystems as operating entities and building on current EE theory along with a range of design theories, this study examines relevant literature with a focus on initial and ongoing operating strategy formulation. The findings argue that effectuation principles can be used to design emerging top-down ecosystems better and proposes a new fourth, temporal effectuation means principle to explain support activity introduction timing and sequencing. By doing so, this paper offers evidence and theoretical elaboration for an extended version of the effectuation concept to build emerging entrepreneurial ecosystems in uncertain resource-constrained locations. These findings could be particularly relevant to inner-city, migrant-based, remote, transition economies or economically/demographically declining regions with a desire to promote entrepreneurship.
Sustainable business models for renewable energy communities and their ecosystem
Authors:   Mondragon Unibertsitatea, Ibarra Dorleta , Igartua Juan Ignacio , Mendoza Joan Manuel F.
Published: June 2023

Renewable energy communities (REC) are key to the sustainable energy transition. However, sustainable business models (SBM) and ecosystems must be developed to ensure the growth and flourishing of REC. This paper presents 16 SBM patterns around the REC ecosystem, describing their sustainability benefits and contribution to sustainable development.
Sufficiency-based Circular Business Models: An established retailers’ perspective
Authors:   ISC Paris, Beulque Rémi , Micheaux Helen ,   AgroParisTech, Ntsondé Joël ,   ISTEC, Aggeri Franck ,   Mines ParisTech, Steux Chloé ,   EPF
Published: June 2023

Taking on the much-criticized concepts of green growth, bioeconomy, or efficiency, both sufficiency and, in certain circumstances, the circular economy, are presented as potential new paradigms that can play a central role in a transition towards a stronger sustainability and enable humanity to stay within planetary boundaries (Alexander, 2012; Bocken and Short, 2020; Jackson, 2005; Raworth, 2017). While businesses have a role to play in the transition, scholars point to the need for more disruptive, sufficiency-based circular business models that focus on slowing material and value loops, but are traditionally less understood practitioners and more difficult to implement in practice (Bocken and Short, 2016; Walker et al., 2021). In this context, this ongoing work focuses on the following research question: how and to which extent can sufficiency-based circular strategies transform established retailers business models? Through a combination of action research and case studies, we aim at providing useful insights to practitioners and the nascent academic literature on the topic (Jungell-Michelsson and Heikkurinen, 2022). Following the foundational article by Niessen and Bocken (2021), we identify new sufficiency-based circular practices that contribute to enrich the business for sufficiency framework. Through concrete examples, we also show that sufficiency-based business models can scale up, and describe some of the associated processes. On a less optimistic note, we highlight some limitations of the observed ongoing upscaling processes, amongst which stand the limited number of retailers that started such a process, the limited contributions of these new practices to overall value creation and capture at the firm level, and clear evidence of rebound effects.
Microfranchises as an innovative approach for empowerment of vulnerable entrepreneurs in post-conflict Colombia
Authors:   EICEA-Universidad de la Sabana, Pérez-Morón James , Thoene Ulf , Alonso Roberto García
Published: June 2023

This article discusses the potential of microfranchises as an inclusive, scalable, and sustainable business model to help vulnerable groups, such as women, ex-combatants, and indigenous people, overcome poverty and unemployment in Latin America. The authors argue that social entrepreneurship, which focuses on creating social value rather than profit, can play a meaningful role in incorporating the social component of assisting and empowering the poor. However, external and internal barriers to the scalability of business models still remain challenging. The authors suggest that more initiatives should value the bottom of the pyramid (BOP) as entrepreneurs and co-inventors, adapting to each country's conditions while generating economic, social, and environmental benefits. The paper examines microfranchises for vulnerable groups in Latin America and how microfranchises can scale to provide a higher impact on society. The authors argue that microfranchising is aligned with BOP 2.0 and 3.0, which focuses on the co-creation of products and services and the entrepreneurial activity of businesses in the BOP. The article highlights the importance of context in the adaptability of entrepreneurs in BOP 3.0 and the positive correlation between the spatial distribution of the microfranchising and the growth of its network of interest groups in the BOP 3.0.
Outline of a Degrowth Business Model Framework
Authors:   Hanze University of Applied Sciences, Dommerholt Egbert
Published: June 2023

For future generations to meet their needs, and to close the global inequality gap, we need to degrow. That is we need to reduce resource and energy consumption to bring the economy back into balance with the living world in a way that reduces inequality and improves human well-being (Hickel, 2020a,b). This transition has consequences for business, because instead of boosting sales companies need to encourage consumers to make do with less, avoiding build in obsolescence, extending product lives to slow disposal and replacement, focusing on satisfying ‘needs’ rather than ‘wants’ and reducing overall resource consumption through conscious changes in sales and marketing techniques, new revenue models and innovative technology solutions (Bocken & Short, 2016). Overall, we can say that companies have to rethink their business models, therefore I specifically aim to answer the following research question: what could a degrowth business model framework look like? Degrowth business models (DGMs) are supposed to serve the dual aim of (1) obeying planetary boundaries whilst simultaneously (2) contributing to reducing inequality and increasing well-being. That is companies need to develop value propositions that, on the one hand contribute to absolutely reducing resource and energy consumption, and on the other are aimed at production of protected needs (Di Giulio & Defila, 2021). Since degrowth is considered an authentic and legitimate interpretation of sustainable development, SDGs 12-16 can serve as proxies for obeying planetary boundaries, whilst the remaining SDGs (minus SDG8.1 -economic growth) can be regarded as proxies for well-being and reducing inequality.
Sustainability orientation in conventional start-ups
Authors:   University of Applied Sciences and Arts Northwestern Switzerland, Milow Uta
Published: June 2023

Sustainable entrepreneurship research often evaluates start-ups that pursue a sustainability goal as a main aspect in their business model or at least follow an ethical motivation. In this study so called conventional start-ups will be examined that do not have this special sustainability focus or ethical motivation as a core of their business model. The question is if and in which areas these numerous start-ups contribute to sustainability in our economy and how this contribution could be improved. Therefore, the sustainability orientation and previous experience in sustainability management of the founding teams was examined. Secondly, the types of ecological and social contributions and their extend were explored. 26 start-ups were interviewed with a semi-structured interview guide. In this explorative study, the interview transcripts were qualitatively analyzed. Many teams claim to have a sustainability-oriented mindset. The experience in managing sustainability issues in previous jobs or projects is low, though. Overall, ecological and social issues play a minor role in the analyzed conventional start-ups' founding processes, and if, they mostly contribute to areas that are easy to implement. The focus of the start-ups was to first enter the market and gain revenue and include sustainability aspects later. As start-ups would have the chance to include sustainability improvements more easily at an early stage, though, support should be developed that offers training and best practice for conventional start-ups. The generally positive attitude of the interviewees towards sustainability is promising. Future research could further explore sustainability contribution patterns of conventional business models to make support more effective.
The Circular Wood KPI-framework
Authors:   Amsterdam University of Applied Sciences, Schoen Tony , Malé-Alemany Marta , Mulder Maarten , Schouten Nico ,   Metabolic
Published: June 2023

Wood is an increasingly demanded renewable resource and an important raw material for construction and materials. Demands are rising, with a growing attention for re-use and upcycling. This opens opportunities for new business models, empowered by the use of digital design and technologies. A KPI-framework has thus been developed to assess the impact of waste wood upcycling, to provide new business perspectives. It is conceived as a tool to enable circular businesses to select the most appropriate circular wood applications for their portfolio. The framework currently consists of eight indicators addressing circularity, environment, society and economics. This paper presents these indicators and shares insights for further development and enhancement of the framework.
Uncovering the meaning of “new business models” and “multiple value creation”
Authors:   Saxion University of Applied Sciences, Koers-Stuiver D.M. , Kamm M.A.A. , Schöller K.
Published: June 2023

This extended abstract reports the research design and preliminary findings of our exploratory mapping review on the research presented at the New Business Model Conference (NBMC). We describe the rationale for an exploratory mapping review, our supervised and unsupervised approach (text mining, topic modeling, Latent Dirichlet allocation (LDA), Latent Semantic Analysis (LSA)) to analyzing the conference proceedings, the preliminary findings, and our next steps. This study aims to examine the used definition, conceptualization, and contextualization of “ new business models”  and “ value creation” within the presented research to understand recent research development better, identify emerging trends, assess the conference’s predictive value based previous research, and draw lessons for the field's future. Our analyses will help to show how words evolve and relate to each other, which helps us look back, reflect, look forward, and predict, which can serve as a stepping stone to conducting a more rigorous systematic literature review and will result in a better understanding of the definitions and conceptualization regarding “ new business models”  and “ multiple value creation”  as well as their linkages In addition, we hope to gain insights from and align the interdisciplinary contributions to new business model research and multiple value creation, identify areas of overlap, and determine the need for theoretical and practical synthesis.
EMOTION RECOGNITION FOR MENTAL HEALTH PREDICTION USING AI TECHNIQUES: AN OVERVIEW
Authors:   Department of Computer Science A.P.S. University Rewa(M.P.), India, Singh Sonali
Published: June 2023

Human facial expressions are a mirror of human thoughts, feelings and human mental states. Facial Emotion Recognition (FER) can provide a social advantage. It's like a form of silent communication. Emotion recognition technology will help to automatically detect the patient's emotions during illness and avoid external acts such as suicide, mental disorders or mental health problems. If we understand all the signs of emotions, we can solve many problems for human beings. Emotion recognition and detection is also useful for healthcare. Through emotional state recognition, we can get information about patients. Recognizing a patient's emotions for a specific disease using artificial intelligence techniques is a challenging task. This article presents recognition, detection and methods for mental health patients. Using artificial intelligence techniques with an emotion detection library and matching emotions to mental health. This article uses an emotional scale to show that there is a link between negative emotions and mental health problems. In this paper, she provided a comprehensive review of AI-based FER methodology, including datasets, feature extraction techniques, algorithms, and recent breakthroughs with their applications in facial expression recognition. In the future, all aspects of FER for different ages would significantly influence the health research community.