bluuebunny/crossref_metadata_2025 huggingface dataset:
An innovative curriculum development experience: Emergency Medical Dispatch role in the Healthcare Transformation Vision of Saudi Arabia
Authors: Alsofayan Yousef , Almakhalas Kharsan , Alabdali Abdullah , Arafat Mohammed , Aljerian Nawfal , Cluntun Ameera , Alshammari Waad , Alharthi Salman , Alhajjaj Fahad , Alowais Jalal , Alsolamy Sami , Mzahim Bandr , Sabbagh Abdulrahman
Published: February 2024

Background
Healthcare medical dispatch systems play a fundamental role in the daily operations of prehospital services. This includes facilitating the interpretation of various dispatch-related systems, receiving incident calls, categorizing cases, guiding proper resources deployment, and providing proper instructions before the arrival of healthcare providers. Considering the Kingdom of Saudi Arabia's (KSA's) health sector transformation plan as part of Vision 2030, developing an Emergency Medical Dispatch (EMD) Program as part of essential prehospital services will allow rapid and competent healthcare delivery. In this study, our purpose is to describe the curriculum development of the EMD Program to improve the training of dispatchers and to share the experience in the interest of better prehospital dispatch systems.
Methods
A selected group of education experts and academics in emergency medical services dispatch were assigned to develop an EMD curriculum over six months. This study aims to describe the approach followed in developing an innovative EMD Program to share the experience and ultimately standardize dispatch-related training programs. The data of this study was collected by reviewing approved documents of the EMD Program including program curriculum, syllabus, logbook, and exam blueprint after approval letters were received from the Health Academy, Saudi Commission for Health Specialties.
Results
The development of the EMD program utilized a consecutive mixed approach starting with a competency-based with backward design method to ensure the achievement of targeted outcomes followed by the Kern Six-step curriculum development model, namely: (1) problem identification and general need assessment; (2) targeted need assessment; (3) goals and objectives; (4) educational strategies; (5) implementation; and (6) evaluation and feedback. This resulted in four comprehensive modules and seventeen competencies in interpreting various dispatch systems, prioritizing incidents, deploying proper resources, and providing pre-arrival instructions throughout the fourteen-week EMD Program.
Conclusion
As part of the health sector transformation plan in KSA, EMD services play a fundamental role in the daily operations of prehospital healthcare services. Developing an EMD Program with a consecutive mixed approach might improve the current operations of EMD services.
Blueprints for resilience: Middle East/North Africa countries' disaster risk reduction education through experts' eyes
Authors: Dinar Hisham , Hummadi Hosam , Alonayzan Deema , Alharbi Lojain
Published: February 2024

Abstract
Background:
All the existing frameworks of Health-Emergency Disaster Risk Management have put great emphasis on the use of educational strategies to be used as a mean of disaster risk reduction (DRR). Thus, this study was conducted to formulate experts' consensus on DRR educational strategies for Middle East/North Africa (MENA) countries.
Methods:
A Delphi study on expert's opinion for DRR educational strategies was carried out through surveys in two consecutive rounds through convenient sampling technique.
Results:
A total of 60 responses were included in this study. Most of the participants were Saudi nationals, physicians (36.7% vs. 33.3% in round 1 and round 2, respectively), and males (73.3%) with experience in disaster management (56.7%) of 5-10 years (60% vs. 53.3% in round 1 and round 2, respectively). Around 80% participants suggested that graduate health professional education should be through problem based learning (PBL) approach (36.7%) (P-value = 0.007). Universal Design for Learning (UDL) framework implementation required provision of multiple means of engagement as priority (P-value = 0.007). Best learning situation category was institution based (60%) with best approach for DRR learning as planned scheduled learning (P-value = 0.000). It was found that best learning situations were lectures and small group sessions (73.3% each) (P-value = 0.165) that were delivered through learning management system (90%) (P-value = 0.103), while the major stakeholders that should be involved in national DRR educational planning were Ministry of Health (90%) (P-value = 0.881).
Conclusion:
Experts have consensus opinion on DRR Educational strategies in MENA countries.
Airway Management with Tracheal Stents -Ventrain® System: Report of Two Cases
Authors:   FEA Anestesiología y Reanimación. Sección Anestesiología Torácica y Neumológica, Hospital Universitario Son Espases, Palma de Mallorca, Spain, Jiménez Paulo A Cano , Fernández M Gallego ,   MIR Anestesiología y Reanimación Hospital Universitario Son Espases, Palma de Mallorca, Spain, Brogi L ,   FEA Anestesiología y Reanimación, Director Unidad de simulación. Hospital Universitario Son Espases, Palma de Mallorca, Spain, Fernández F Barturen
Published: February 2024

In our case experience with the use of VENTRAIN system and the reconstruction of 3D images and videos, they would constitute an alternative in the management of oxygenation, ventilation and isolation of the air route when performing this procedure
Integration of Mapping Malnutrition Cases in Toddlers Based on Geographic Information System With Media Communication Information Education in Health
Authors: Wiryawan I Gede , Perwiraningrum Dhyani Ayu , Hudori Huda Ahmad
Published: February 2024

In this study, the stunting case incidence mapping system has been further developed, and its integration with Communication, Information, and Education (KIE) media in the health sector. This study aims to increase knowledge about the world of health, especially related to stunting, through the integration of KIE media into data visualization of stunting cases. The results of developing this system integration include a fairly good level of acceptance from the community, as evidenced by the results of User Acceptance Testing (UAT) carried out on health workers and mothers with children under five. Functional testing of the system has also been completed with the conclusion that several features need to be improved. UAT testing obtained results worth 87%, and from functionality testing a success rate reached 90%, but all improvements have been completed. Future studies that can be carried out are to implement this integrated system more widely.
E-Advertorial Design using the Addie Model as a Marketing and Health Promotion Strategy
Authors: Susindra Yoswenita , Ayu Dessya Putri , Widyawati Agatha , Kartika Ria Chandra
Published: February 2024

Teaching factory Nutrition Care Center (NCC) is a nutrition service center for the wider community in health consultations, but so far patients only come from internal campuses. NCC has experienced a decline in the number of visits every months. The decrease in the number of visits to NCC may be caused by many things, and one of them caused by the marketing strategy. NCC needs to introduce its products by using effective messages such as e-advertorials. E-advertorials are more effective in creating brand awareness than other advertisements. The aim of this research is to design an EAdvertorial as a marketing and health promotion strategy to introduce NCC service products to the general public and increase patient visits. The research method uses a qualitative approach with descriptive qualitative research type. The design study was research and development. Data collected by questionnaire, interview, and literature study. The development of E-Advertorial uses ADDIE model. The results of the validation assessment score is 90.8%, which means this media is suitable for publication. The feasibility test assessment score is 80%, which means the E-Advertorial media is very good. E-advertorials can be used as a eligible promotional medium that is interesting, informative and easily accessible.
Optimizing Nutrition Care Management at Nutrition Care Center (NCC)
Authors: Wijayanti Rossalina , Dewi Riskha Dora Candra , Farlida Sustin , Nuraini Novita
Published: February 2024

In nutrition care services, the creation and storage of medical records at the Nutrition Care Center (NCC) are still relatively simple and paper-based or manual. Additionally, management challenges, in the form of system constraints, are one of the obstacles to healthcare management at NCC. Therefore, there is a need for optimizing healthcare management at NCC. The aim of this study is to optimize nutrition care management at the NCC clinic through the use of EMR (Electronic Medical Records) facilitated by QR Codes and the implementation of a Whatsapp Bot. The results indicate that optimizing Nutrition Care Management through the Implementation of EMR with QR Codes and Whatsapp Bot simplifies nutritionists' access to previous client allergy and therapy history in one view and facilitates clients in accessing their medical record number without a physical card. This research has also designed a system that can be used both through web and mobile platforms
The Nutrition Counseling Improve Volleyball Athelets Knowledge
Authors: Permadi M Rizal , Purnasari Galih , Renamastika Stephani Nesya
Published: February 2024

The dietary intake of athletes is crucial for attaining peak performance, sustaining physical fitness, preventing the risk of injury, and speeding post-competition recovery. A prevalent issue among athletes is insufficient food consumption relative to their nutritional requirements, resulting from a limited understanding of proper dietary practises. The objective of this study is to increase athletes' understanding of dietary consumption through the provision of nutritional guidance to athletes. The study was conducted on ten volleyball atheletes who were in the process of training for the PORPROV (Pekan Olahraga Provinsi) Jawa Timur VIII tournament in 2023. This research used the pre-experimental design method . The research design uses one group pre-test post-test design. The data collected includes body weight, height, food intake and nutritional knowledge of athletes. The analysis used a one sample t-test to see the athletes' food intake and knowledge before and after being given nutritional counseling. The results of this study were a significant increase in athletes' knowledge and energy intake (p <0.05), the average athlete knowledge score before nutritional counseling was 52.5 and after nutritional counseling it was 74.5. The mean energy consumption before to receiving nutritional counselling was 1794.6 kilocalories (kcal), while after receiving nutritional counselling, it increased to 2141.8 kcal. Providing nutrition counselling to volleyball athletes can improve their understanding of dietary requirements and improve their food consumption, finally leading to optimal performance. The government should provide nutritional counseling services for athletes
Hospimeal: Website Based Nutrition Care Process Digitalization
Authors: Restuti Arisanty Nursetia , Jannah Miftahul , Iqbal Muhammad
Published: February 2024

The nutrition Care Process (NCP) is a systematic approach or standard to provide comprehensive nutritional care for patients or clients. NCP consists of 4 interrelated steps, namely nutrition assessment, nutrition diagnosis, nutrition intervention, nutrition monitoring and nutrition evaluation. Implementation of NCP in many health services facilities face some barriers because of using manual NCP, such as human error, time-consuming, and incomplete documentation. Digitalization of NCP has proven to be beneficial in terms of efficiency of time and provision of electronic data to improve patient services. This study aimed to develop Hospimeal as a website-based Nutrition Care Process (NCP). The development of the web-based NCP application carried out in this study used the waterfall method. The stages of the waterfall method are need analysis, study of literature and data retrieval, system requirements, system planning, system implementation and testing, digitalization of NCP management in website. Digitalization of Standardized Nutrition Care Process (NCP) management can be developed in the form of a website called Hospimeal. This website provides nutritional care to patients/clients starting from nutrition assessment, nutrition diagnosis, nutrition intervention, nutrition monitoring, and nutrition evaluation. The Hospimeal website can be operated by the relevant nutritionist/dietitian. At the beginning of the display there is a Login menu which can be used by nutrition-ists/dietitians to enter the website
Barriers and facilitators of adherence to tuberculosis treatment in children and adolescents
Authors: Santos Marina , Costa Bruna , Rodrigues Maria Clara , Cardoso Claudete
Published: February 2024

Introduction: Tuberculosis (TB), an infectious and contagious disease, requires prolonged treatment and usually affects socially vulnerable patients, which increases the risk of abandonment during its course. Children and adolescents are susceptible to this infection, requiring adequate treatment for a favorable clinical outcome. It is known that adherence to TB treatment is the main obstacle to cure the disease, and it is important to know the factors that could influence this adherence. The aim of this review is to analyze the factors that interfere with adherence to TB treatment in children and adolescents. Metodology: This systematic literature review was conducted by searching the descriptors Tuberculosis (OR Tuberculosis) AND Adherence (OR Adhesion) in the PubMed, Scielo and Lilacs databases. Articles about the adherence of children and adolescents to TB treatment were included. Duplicates were excluded. The selection of articles for review was conducted in the following steps: analysis of titles, reading of abstracts and full articles. At the end of the selection, 28 articles were reviewed. Results: The main barriers to adherence to TB treatment were: prolonged treatment time, adverse effects, caregivers lack of knowledge about the disease and latent infection and socioeconomic status. The main facilitators were: shorter treatment, directly observed, financial support and advice from patients and caregivers. HIV-TB co-infection can increase adherence due to routine medication intake, or decrease due to the increase in adverse effects. Conclusion: The acknowledgement of the facilitators and barriers to adherence allows directing the necessary efforts to promote best response to TB treatment.
PENGARUH ENTERPRISE RISK MANAGEMENT, PROFITABILITAS DAN KEPEMILIKAN MANAGERIAL TERHADAP NILAI PERUSAHAAN ASURANSI DI BURSA EFEK INDONESIA
Authors: Ismanto Juli , Rosini Iin , Nofryanti
Published: February 2024

This study aims to determine the impact of corporate risk management disclosure, profitability, and managerial ownership on firm value. Secondary data comes from the financial statements of insurance companies listed on the IDX between 2016 and 2021. Sixteen companies were used as research objects for six years of observation, resulting in 96 observations. This study used panel data regression analysis using Eviews12 data processing as the mechanism. The research findings show that enterprise risk management and managerial ownership do not affect firm value. On the other hand, profitability proxied by ROA has a significant and negative influence on firm value. Therefore, it can be concluded that profitability significantly affects firm value, with a negative coefficient indicating that low ROA means declining profits, reduced competitiveness, inadequate capital, and future business turmoil.
FAKTOR TEKNOLOGI TERHADAP ADOPSI BIG DATA PADA ERA TRANSFORMASI DIGITAL
Authors: Ratnasari Mega Ayu , Hasnawati
Published: February 2024

This study aims to analyze the influence of technological factors on the adoption of big data analytics in the digital transformation era. The population in this study are companies in Indonesia, especially those in Jabodetabek that have adopted big data in their operational systems. The sample in this study was 205 respondents using a purposive sample method. The type of data in this study is primary data in the form of a questionnaire survey. Data were analyzed using multiple regression techniques using SPSS ver 25. The study results show that relative advantage, compatibility, and complexity positively affect companies' interest in adopting big data. But security negatively affects companies' interest in adopting big data.
ANALYSIS OF THE FINANCIAL PERFORMANCE OF ORIGINAL LOCAL GOVERNMENT REVENUE OF KLATEN
Authors: Rachmansih Bernadetha Kurnia Dewi , Asrihapsari Andi
Published: February 2024

This study aims to discover the financial performance of the Original Local Government Revenue (Indonesian: Pendapatan Asli Daerah, abbreviated PAD) of the Klaten Regency Local Government from 2018 to 2022. This study is quantitative and descriptive. Data analysis was performed using the independence ratio, effectiveness ratio, and contribution ratio. The results show the financial performance of the PAD of the Klaten Regency is very low. It is seen from the regional financial independence ratio from 2018 to 2022 that has a percentage of 17.57% with the pattern of instructive relationships. The PAD effectiveness ratio from 2018 to 2022 shows very effective criteria because the revenue exceeds 100% with a percentage of 115.11%. The PAD contribution ratio from 2018 to 2022 shows moderate criteria because it has a percentage of 25.00%. In addition, there are still several obstacles to increasing PAD experienced by the Klaten Regency Local Government. Based on the results of this study, the researchers give some recommendations, namely optimizing sources of PAD that have not been developed well, digitizing the payment system, promoting Local Government Owned Enterprises directly to the public through social media, and putting efforts to minimize obstacles to increasing PAD.
Some mechanisms of formation of intrapersonal and interpersonal conflicts related to the personality characteristics of the Dominant and Subordinate person in the parental family
Authors: Sennitskaya Elena Vladimirovna
Published: February 2024

The object of the study is the patterns of formation of intrapersonal and interpersonal conflicts, which are the result of the desire to rise above the Dominant family member and not live life as a subordinate family member. The conflicts arising in the process of realizing the following desires were analyzed: 1) to realize a dream that the Dominant could not realize; 2) to possess the skills and qualities of people in relation to whom the Dominant felt feelings of delight, respect, admiration, awe, envy; 3) to do what the Dominant was afraid of (or do something that could frighten the Dominant); 4) not to fall into the category of people that the Dominant considered "weaklings"; 5) to do something that could cause impotent rage (panic) in the Dominant; 6) to have such skills or qualities that the Dominant was proud of, took credit for; 7) to have those skills and qualities that the person possessed, who has managed to rise above the Dominant One in some way; 8) marry a person who will help realize the above desires, etc.n This work is a qualitative study of a structured interview, which was previously the subject of a quantitative study published earlier. The detailed answers of the subjects were classified according to the types of conflicts described in them. The novelty lies in the fact that on the basis of these basic aspirations, a number of private needs have been identified, the inability to satisfy which leads to intrapersonal and interpersonal conflicts. A cognitive distortion has been revealed regarding the "helplessness" and "inoffensiveness" of people of the same sex as the Subordinate. The following personality structure is proposed: 1) ideas about what is "strong" behavior (based on the child's observation of the Dominant behavior, which ensures success in the eyes of a Subordinate); 2) ideas about what is "weak" behavior (based on observation of the Subordinate's behavior, which, from the child's point of view, makes him a slave) 3) ideas about "strong" and "weak", "decent" and "unworthy" behavior that exist in society. It is assumed that the driving force of personality development is the resolution of contradictions found by the child between these three elements.
İndirimli Orana Tabi Konut Teslimlerinde KDV İade Süreci ve VEDOP Uygulaması
Authors: ÖS Mehmet
Published: February 2024

Bu çalışmanın amacı, Türkiye’de indirimli orana tabi konut teslimlerine ilişkin KDV iade sürecini Vergi Daireleri Tam Otomasyon Projesi (VEDOP) kapsamında incelemektir. İkamet amaçlı konut olarak imal edilen yapıların tesliminde indirimli KDV oranının teknolojik dönüşümler sonucunda dijital ortamda uygulama süreçleri açıklanmaktadır. Bu bağlamda TÜİK 2024 yılı konut satış verileri kullanılmıştır. Bu veriler ile 150 m2 kullanım alanına sahip konutların üretilen konutlar içerisindeki payı mukayese edilmiştir. Bu konutların imalatında oluşan maliyetlerin büyük bir kısmı genel KDV oranına tabidir. Bu durumda, konut imalatında oluşan maliyetlerinin KDV oranı, konutların KDV oranından yüksek olması durumu ortaya çıkmaktadır. Böylece, inşaat firmalarınca yüklenilen KDV’nin indirim yoluyla giderilememe sorunu ortaya çıkmaktadır. Günümüzde teknolojik gelişmeler ile KDV iade süreçleri çözümlenmektedir. KDV iade süreçlerinin dijital ortamda gerçekleşmesinin vergi kayıp ve kaçaklarının önüne geçilmesi noktasında önemli olduğu düşünülmektedir. Ayrıca, dijitalleşme ile birlikte gerçek satış değeri ile tapu değeri arasında oluşabilecek matrah farklarının da önüne geçilmiş olacaktır. Sonuç olarak dijitalleşme ile indirimli orana tabi konut teslimlerinde KDV iade süreçlerinin daha yalın vergi kayıplarının önlenmesine katkı sunulması açısından yararlı olacağı düşünülmektedir.
Análise de sobrevivência em idosos com Covid-19
Authors: Leite Maria Amanda Pereira , Leal Natalia Pessoa da Rocha , Nova Felícia Augusta de Lima Vila , Pereira Renata Rabelo , Farias Rayane de Almeida , Monteiro Edilene Araújo , Bittencourt Greicy Kelly Gouveia Dias , Pontes Maria de Lourdes de Farias
Published: February 2024

Objetivos: Caracterizar os casos da covid-19 em idosos paraibanos, no primeiro ano da pandemia; calcular a probabilidade de sobrevivência. Métodos: Pesquisa epidemiológica, descritiva e retrospectiva, realizada com dados secundários provenientes do e-SUS Notifica, coletados na Gerência de Vigilância Epidemiológica da Secretaria de Estado da Saúde da Paraíba. Foram incluídos nesse estudo os 26.924 casos da covid-19 em idosos, notificados no período de fevereiro de 2020 a fevereiro de 2021. Resultados: Mulheres foram mais afetadas, pardos constituíram maioria, houve prevalência das doenças cardiovasculares e diabetes. Indivíduos nas faixas etárias mais avançadas apresentaram mais chances de falecer; ser do sexo masculino aumentou em 34% o risco de óbito; ser da raça/cor parda aumentou em 43%. A probabilidade de sobrevivência estimada foi de 98,3% em até 30 dias de sintomas, 97,6% em 60 dias e 96,5% em 120 dias. Conclusão: Foi possível identificar o perfil epidemiológico dos idosos acometidos pela covid-19, contudo, reforça-se a necessidade do estabelecimento de ações que visam a mitigação do vírus nesse público.
A importância do pré-natal odontológico na rede pública de saúde em Manaus, AM
Authors: Castro Leticia Gadelha de , Barreto Victoria Luene Ramos , Santos Vittoria Palmira de Souza , Meira Gabriela de Figueiredo , Sá Juliana Lopes de
Published: February 2024

Objetivo: Verificar a influência das condições bucais em gestantes que realizaram o pré-natal no Sistema Único de Saúde (SUS), por meio de Unidades Básicas de Saúde (UBS) de Manaus-Am, Brasil. Métodos: A metodologia utilizada foi de estudo observacional transversal com gestantes de 18 a 40 anos de idade em UBS de Manaus-Am, Brasil, avaliando as variáveis clínicas de acordo com a metodologia previamente descrita pela OMS. Resultados: Durante o pré-natal, é necessário que a gestante obtenha informações sobre a importância da saúde bucal, pois pode ocorrer o surgimento de alterações bucais características da gestação, e com isso, a necessidade de cuidados intensificados acerca da alimentação e higiene bucal, e a necessidade de cuidados profissionais redobrados. Dentre as condições bucais avaliadas estão a cárie dentária e sangramento gengival. Conclusão: Foi avaliado o nível de conhecimento das gestantes sobre saúde bucal através de um questionário sobre saúde bucal na gravidez. Durante o estudo conseguimos evidenciar os problemas bucais que essas mulheres apresentavam e a necessidade de intensificar os cuidados realizados pelas equipes multidisciplinares.
Tecnologia aplicada à saúde: perspectivas para o climatério
Authors: Oliveira Amaraline de Souza , Pinto Diego dos Santos , Trindade Gabriela Miranda , Silva Júlliam Kéthelem Teodoro da , Elias Lílian Salomão , Bastos Cristiane Perácio
Published: February 2024

Objetivo: Revisar sobre a importância da tecnologia aplicada no campo da saúde e suas perspectivas para o Climatério. Revisão bibliográfica: A tecnologia aplicada à saúde por meio de dispositivos móveis - Saúde Móvel - ganhou espaço nos últimos anos pela facilidade de acesso, trazendo benefícios como informações seguras, monitoramento do paciente e criar uma interatividade entre este e o profissional de saúde de maneira não presencial. O Climatério é um importante período na vida da mulher que demanda de uma atenção específica por parte dos serviços de saúde e as ferramentas tecnológicas possuem diversos recursos para ampliar essa assistência, visto que há uma deficiência de informações e de tecnologias aplicadas ao Climatério. Considerações finais: O Climatério representa um marco na vida da mulher, caracterizado pelo final da fase reprodutiva. Entretanto, pode estar relacionado a prejuízo na saúde física e psicossocial. Embora a utilização das tecnologias em saúde seja uma realidade em muitas áreas, ainda é discreta quando se trata de Climatério. É preciso investir em ambientes voltados para a educação em saúde no Climatério pois a utilização de recursos tecnológicos como os aplicativos móveis garantem um ambiente informativo, de fácil acesso, seguro e cientificamente estruturado para auxiliá-las durante o processo da senescência ovariana.
Avaliação dos fatores que interferem na adesão das mulheres ao exame de papanicolau
Authors: Nascimento Ana Carolina Florenço , Assis Danielle Gonçalves de , Souza Gabriela Matos de , Souza Manuela Rodrigues Pires de , Cunha Maria Eduarda Uliane Sihle , Uwada Thaís Miki
Published: February 2024

Objetivo: Estabelecer quais são os fatores que interferem positiva e negativamente na adesão das mulheres ao exame de Papanicolau. Métodos: Trata-se de um estudo quali-quantitativo do tipo transversal, conduzido com 233 mulheres, a partir de um questionário socioeconômico composto por 9 questões e outro de avaliação de conhecimento, composto por 5 questões. Sendo assim, foram aceitas respostas de mulheres de 25 a 65 anos, residentes no estado de São Paulo, que já tinham praticado relação sexual e que não possuíam diagnóstico prévio de Câncer de Colo de Útero. Resultados: Das mulheres que declararam importância na realização do exame de Papanicolau, 98,7% o realizaram, enquanto, entre as que não acreditam ser importante, a taxa foi de 0%. Mulheres que possuíam alguma religião, foram associadas positivamente a realização do exame preventivo. Os fatores que não interferiram na realização do exame por não haver associação estatística significativa foram: renda salarial e escolaridade. Conclusão: Conclui-se que os fatores associados positivamente à adesão ao exame de Papanicolau, são: conhecimento sobre sua importância e possuir alguma religião.
Mortalidade por doenças infecciosas e parasitárias no Nordeste do Brasil de 2000 a 2019: estudo ecológico de série temporal
Authors: Silva Wady Wendler Soares Veras e , Rocha Maria Izabel Félix , Silva Filho Francisco Artur e , Mello Gustavo Wilson de Sousa , Matos Ludmilla Karen Brandão Lima de , Teixeira Kelly Sivocy Sampaio , Barros Filho Bartholomeu Araújo , Almeida Buana Carvalho de , Ferreira Antônio Hosmylton Carvalho
Published: February 2024

Objetivo: Analisar o perfil sociodemográfico e a tendência temporal da mortalidade por doenças infecciosas e parasitárias no Nordeste brasileiro de 2000 a 2019.  Métodos: Estudo descritivo de séries temporais, que utilizou o banco de dados do Sistema de Informação sobre Mortalidade no período de 2000 a 2019. Foram empregadas técnicas de análise de padrão temporal e regressão pelo método Joinpoint. Os resultados foram considerados estatisticamente significantes quando p ≤ 0,05. Resultados: Na região, foram registrados 260.192 óbitos por doenças infecciosas e parasitárias no período, correspondendo a uma taxa média de mortalidade de 24,4 óbitos por 100 mil habitantes. Houve tendência de crescimento significativo da mortalidade por esta causa no período de 2010 a 2019 (Variação percentual anual= 1,51%; IC95%: 0,70 – 2,40; p<0,001) Conclusão: Houve um crescimento na mortalidade por doenças infecciosas e parasitárias no período estudado, com maior número de casos entre pessoas do sexo masculino, idosos, pardos, solteiros e com nenhuma escolaridade.
Alterações auditivas em adolescentes e adultos jovens expostos a ruídos de lazer
Authors: Andrade Beatriz Raposo , Pereira Renata Lúcia Aparecida Queiroz , Gewehr Nayra , Rabelo Yasmim da Rocha , Gonçalves Josyane Borges da Silva
Published: February 2024

Objetivo: Avaliar a prevalência de alterações auditivas em adolescentes e adultos jovens expostos à ruídos de lazer.  Métodos: É uma revisão integrativa da literatura com uso das bases de dados PUBMED, SCIELO e LILACS. Utilizado os seguintes descritores “Perda auditiva  induzida por ruído” OR “Zumbido”  OR “Ruído”, associado  (AND) aos descritores “Adolescente”, “AND” “Adulto jovem” nos idiomas inglês e português. Assim, identificou-se 800 artigos, após seleção de artigos grátis e completos restaram 158, que foram reduzidos a 8 artigos após a aplicação dos critérios de inclusão e exclusão, análise dos títulos e resumos, 4 artigos selecionados por busca manual foram inclusos na amostra, tendo em vista sua relevância, totalizando 12 artigos. Resultados: Após análise dos estudos, verificamos que os instrumentos de avaliação foram muito variados, zumbido foi a queixa mais prevalente relacionada à exposição à ruídos de lazer e não houve uma relação entre a exposição à ruídos de lazer e perda auditiva permanente. Considerações finais: Considera-se que alterações temporárias no limiar auditivo devem ser valorizadas e o acompanhamento a longo prazo desses indivíduos se faz necessário, para o monitoramento de alterações auditivas permanentes ou precoces.
O uso dos Anticoagulantes Orais de Ação Direta (DOACs) como terapia anticoagulante na COVID-19
Authors: Sousa Eduardo Macedo , Ferreira Neto Gustavo Elias , Lobo Henrique Moura , Naves Icaro Gabriel , Menezes Junior Antônio da Silva
Published: February 2024

Objetivo: Identificar os efeitos da utilização dos Anticoagulantes Orais de Ação Direta (DOACs) na infecção pelo SARS-CoV-2 como terapia anticoagulante no curso da doença. Métodos: trata-se de um estudo do tipo revisão integrativa, no qual utilizaram-se as bases de dados: Medical Literature Analysis and Retrievel System Online (MEDLINE/PubMed), Literatura Latino-americana e do Caribe em Ciências da Saúde (LILACS), Índice Bibliográfico Espanhol em Ciências da saúde (IBECS) e Scientific Electronic Library Online (SciELO), com os seguintes descritores, em ciências da saúde (DEcS): ”(Covid OR long Covid OR post Covid OR Post-Acute COVID-19 Syndrome) AND Factor Xa Inhibitors”. Utilizou-se como pergunta norteadora: os DOACs podem ser usados de forma segura no contexto da infecção pela COVID-19 como terapia anticoagulante? Resultados: A amostra final foi composta por 15 artigos os quais evidenciaram efeitos adversos bem como resultados otimistas a respeito do uso de DOACs na COVID-19. Considerações finais: DOACs parecem ser vantajosos a nível ambulatorial, porém restam dúvidas quanto às possíveis interações medicamentosas indesejáveis.
Relação da doença inflamatória pélvica com o uso de dispositivos intrauterinos
Authors: Rodrigues Isadora Borges , Ramalho Beatriz Vieira , Aranha Júlia Cavalcante , Zanuso Gabrielli , Gonçalves Itamar Magalhães
Published: February 2024

Objetivo: Elucidar a relação entre o uso de Dispositivo Intrauterino (DIU) e a Doença Inflamatória Pélvica (DIP). Métodos: Trata-se de uma revisão integrativa, realizada a partir de um levantamento bibliográfico nas bases de dados LILACS e PUBMED, considerando estudos em língua portuguesa e inglesa, correspondentes ao período de 2017 a 2022. Para seleção dos estudos foram aplicados os critérios de inclusão e exclusão, além de se observar as metodologias aplicadas e os resultados alcançados pelos autores. Resultados: Dos 1515 artigos encontrados, apenas 43 foram elegíveis para leitura completa, que, uma vez realizada, classificou somente 6 artigos para uma análise minuciosa. Considerações finais: A relação entre o DIU e a DIP é pouco prevalente, com relatos raros, na ordem de 3%. A maioria dos ginecologistas prescreve com segurança o dispositivo para nulíparas, sugerindo que, com a devida orientação e acompanhamento médico adequado, os benefícios do seu uso superam o risco da DIP.
Custos das hospitalizações de pacientes com pneumonia
Authors: Lima Francisco Wallison Barbosa de , Targino Bruna Cristina Cardoso Martins , Barroso Lysrayane Kerullen David , Sampaio Renata Sousa , Oliveira Thais Barbosa de , Targino Luciano Pereira , Fonteles Marta Maria de França
Published: February 2024

Objetivo: Descrever os custos das internações por pneumonia no Ceará no período de janeiro a dezembro de 2021 após estabilização dos casos da COVID-19. Métodos: Trata-se de um estudo do tipo custo-consequência, ecológico, de tendência temporal, a partir de dados secundários dos custos de hospitalização por pneumonia no Brasil, por unidade federativa e por região brasileira, notificados no período de janeiro a dezembro de 2021 no SIH/SUS, disponível no sítio eletrônico do DATASUS, via Tabnet. Resultados: Foram notificados 167 casos de pneumonia, em 2021, sendo o CID J-18 o mais prevalente. No segundo semestre, se destacou por obter mais notificações com 63,27%. Os pacientes com faixa etária entre 60 e acima de 80 anos representam a maior quantidade de notificações com 76 casos, e 131 casos caracterizam aqueles que ficaram internados com tempo de até 7 dias, ademais os custos totais com a hospitalização dos pacientes chegaram a R$ 14.164.371,00, com um custo médio por paciente de R$ 2.000.818,00.  Conclusão: Conclui-se que há necessidade de que a gestão de custos associado ao impacto se torne rotina entre os gestores de saúde, a fim de reduzir custos e racionalizar o uso deste.
Diagnóstico e tratamento de hérnia inguinal em atletas
Authors: Machado Melicio Henrique de Almeida , Machado João Felipe de Almeida , Pereira Neto Raimundo , Oliveira Neto Jorge Maurilio Ferreira de , Lima Arthur Vinícius Almeida , Santos Daniel Oliveira , Souza João Gabriel Dourado Oliveira , Farias Edkayo Cezar Fonseca de , Ferreira Filho Ecliê Santos , Figueiredo Maria Bernadete Galrão de Almeida
Published: February 2024

Objetivo: Avaliar particularidades do diagnóstico e do tratamento das hérnias inguinais (HI) em atletas. Método: Trata-se de uma revisão integrativa realizada através das bases PMC, BVS, Acervo+ Index Base, LILACS e SciELO, através dos descritores associados ao operador booleano “AND”, de forma que fosse ampliado os resultados. Resultados: No total, identificou-se 721 artigos nas bases selecionadas, desses 56 foram submetidos a leitura do resumo, dos quais 30 foram selecionados para leitura integral. Após isso, restaram 9 artigos para compor a base de dados dessa revisão. Constatou-se que a HI verdadeira é um dos diagnósticos de exclusão de pubalgia de atleta, nessa revisão a maioria dos estudos constataram um número importante de atletas acometidos por essa doença com queixa de dor na virilha. Seu diagnóstico é realizado, no geral, com anamnese e exame físico, podendo ser complementado com exames de imagem, pois a HI pode estar clinicamente ausente. O tratamento cirúrgico foi resolutivo para queixa dolorosa, permitindo retorno dos atletas as atividades. Considerações finais: A hérnia inguinal verdadeira pode estar presente nos pacientes com pubalgia do atleta. Essa queixa deve ser investigada nesses pacientes, e quando identificada, a correção cirúrgica se mostra eficaz para melhora dos sintomas álgicos.
Potencialidades e desafios no empreendedorismo empresarial da enfermagem
Authors: Mendonça Fernanda Santiago Santos , Haddad Maria do Carmo Fernandez Lourenço , Dadalt Patrícia Aroni , Neves Igor Fernando
Published: February 2024

Objetivo: Identificar na literatura cientifica as potencialidades e desafios do empreendedorismo empresarial na enfermagem. Métodos: Revisão integrativa elaborada conforme o acrônimo População, Conteúdo e Contexto (PCC) realizada em julho de 2023 em oito bases de dados, a partir dos descritores empreendedorismo, empreendedores, enfermagem, entrepreneurship, entrepreneurs, nursing, nurse. Foram incluídos artigos disponíveis na íntegra relacionados ao objetivo do estudo, que apresentassem como população o enfermeiro empreendedor, publicados em qualquer idioma e como critérios de exclusão artigos de revisão, teses e dissertações, resultando em 16 artigos finais. A análise dos dados ocorreu pelo processamento no software Iramuteq®. Resultados:  Formaram-se em três classes finais que representaram as potencialidades e os desafios para o empreendedorismo empresarial na enfermagem: ética e seu potencial empreendedor; desafios do enfermeiro empreendedor na administração dos seus negócios e inovação e empreendedorismo na enfermagem. Considerações finais: durante o processo empreendedor na enfermagem ocorrem potencialidades e desafios, portanto há necessidade de se inovar, criar, pensar estrategicamente, reconhecendo também quando o empreendimento não está dando mais retorno financeiro.
ANTIOXIDANTS, BIOCHEMICAL, AND HEMATOLOGICAL PARAMETERS CHANGE IN WORKERS OCCUPATIONALLY EXPOSED TO RADON INHALATION AT CERTAIN CONSTRUCTION MATERIAL INDUSTRIES IN ERBIL, IRAQ
Authors: Othman Sardar Q. , Mohammed Sarbaz I. , Ahmed Ali H.
Published: February 2024

This study examined the effects of radon on the endogenous antioxidants, biochemical, and hematological parameters of workers in Erbil, Iraqi Kurdistan. This was carried out to ascertain how radon affects the health of those who work in certain factories producing building materials. The case study group consisted of 70 workers, who were then divided into seven subgroups (gypsum, cement plant, lightweight block, marble, red brick 1, crushed stone, and concrete block 2), while the control group consisted of 20 healthy volunteers. The total antioxidant capacity (TAC), levels of carcinoembryonic antigen (CEA), superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPX), the complete blood count (CBC), and liver function tests were evaluated. The statistical analysis revealed that the antioxidant activities and CEA levels between the case study group and the control group differed significantly. Also, antioxidant enzyme activities and indoor radon concentration, the annual effective dosage, were found to be highly significantly correlated by Pearson and Spearman analyses in the case study group. Additionally, the results demonstrated a substantial correlation in the data between the levels of CEA biomarkers and radon (r=0.478, p˂0.000). The present results showed that radon concentration increased alanine aminotransferase (ALT) activity in a radon concentration-dependent manner (r=0.263 and p ˂0.05). The aspartate aminotransferase (AST), alkaline phosphatase (ALP), and total bilirubin activities, on the other hand, were not significantly affected by radon. The most significantly influenced CBC parameter was the low white blood cells (WBC) in the case study group compared to the controls. Low platelet count (PLT) was the second-highest problematic metric. The other CBC values, however, did not significantly differ between the research group and the control group. This study offers a preliminary image of the endogenous antioxidant systems in employees, especially to show a connection between radon and the occurrence of cancer among workers in Iraq Kurdistan Region.
Pinched Tube Method for Gas Sample Transfers
Authors: Farooq Muhammad Umer , Thorn Jr. Robert P. , Gillespie Andrew K. , Lin Cuikun , Duncan Robert V.
Published: February 2024

When transferring small volumes of gas samples between laboratories, cold welded, pinched copper tubes offer an inexpensive and convenient solution. In this paper, we outline the preparation, loading, transfer, and analysis methods used in a multi-campus, collaborative study under the United States Department of Energy. This gas transfer method has been utilized on samples from novel nuclear reactions, where the presence of low-mass gas isotopes is often used as an indicator of a successful reaction. Low-mass isotopic gas analysis requires careful preparation and handling to mitigate contamination, primarily resulting from air intrusion. The pinched tubes were found to be hermetic until punctured using a saddle valve prior to gas analysis with an analytical instrument. The integrity of this transfer method was proven using a Fourier Transform Ion Cyclotron Resonance (FT-ICR) mass spectrometer. We also discuss hermiticity measurements during the tube puncturing process.
Artificial Metalloenzyme Catalyzed Enantioselective Carboamination of Alkenes
Authors: Yu Kun , Tachibana Ryo , Rumo Corentin , Igareta Nico , Ward Thomas
Published: February 2024

Relying on ubiquitous alkenes, carboamination reactions enable the difunctionalization of the double bond by the concurrent formation of a C–N and a C–C single bond. In the past years, several groups have reported on elegant strategies for the carboamination of alkenes relying on homogeneous catalysts or enzymes. Herein, we report on an artificial metalloenzyme for the enantioselective carboamination of dihydrofuran. Genetic optimization, combined with a Bayesian optimization of catalytic performance, afforded the disubstituted tetrahydrofuran product in up to 22 TON and 85% ee. X-ray analysis of the evolved artificial carboaminase shed light on critical amino acid residues that affect catalytic performance.
Iron-Catalyzed Aza-Annulative π-Extension with Alkynes via C–H Activation using an Oxidative Auxiliary
Authors: Zhang Yan , Fukuma Shota , Shang Rui , Nakamura Eiichi
Published: February 2024

Abstract: Aza-annulative π-extension (AAPE) reactions offer a potent pathway to create novel donor-acceptor conjugated materials by integrating an imine moiety into the conjugated system, serving as an electron-accepting unit. However, the affinity of late-transition metals for conjugated π-systems, coupled with their elevated cost, has posed significant challenges, restricting efficient AAPE reactions on straightforward C–H substrates for developing conjugated new materials. In this study, we unveil an iron-catalyzed C–H activation methodology, facilitating AAPE with diverse internal alkynes and employing oxime ether as both a self-oxidizing auxiliary and nitrogen source, derived seamlessly from accessible carbonyl compounds. The AAPE reaction was enabled by using trisphosphine as a ligand, and isobutyl aluminum(III) catecholate as a base. By using the reaction, we discovered an aza-oxa[5]helicene from dixanthone as a potential circularly polarized luminescence material and two narrow-band-emissive molecules from easily accessible pentacene-6,13-dione and quinacridone, which emit blue and yellow light with high color purity and high fluorescence quantum yield. These findings emphasize the potential of iron-catalyzed C–H activation in expanding the range of donor-acceptor-type conjugated materials for organic electronics.
Factors influencing the sexual drive of Russian women of reproductive age in the digital age
Authors: Fedorova Anna I. , Kazakova Anna V. , Chechko Svetlana M. , Kozupitsa Gennadiy S. , Dufinets Irina E.
Published: February 2024

Aim. To assess the impact of age, number of sexual partners, having children, family income, and time spent with a smartphone or computer on the sexual drive of women of reproductive age in the era of information technology.
Materials and methods. A study of the sexual drive of 79 women aged 18–35 in family (partner) relationships was conducted. The well-established international Female Sexual Function Index was used. Respondents also answered questions about some aspects of personality and social status. The results were evaluated using the methods of mathematical statistics: descriptive statistics, correlation, determination, and logit-regression analyses.
Results. The intensity of sexual drive correlates with a woman's age, the number of sexual partners, and the family income. There was no correlation between the level of a woman's sexual drive and having children and the time women and their partners spend with computers and smartphones.
Menopause and premature ovarian insufficiency in rheumatic diseases: A review
Authors: Panevin Taras S. , Ledina Antonina V. , Zotkin Evgeniy G
Published: February 2024

Premature ovarian insufficiency (POI) is a clinical syndrome defined as loss of ovarian function before the age of 40 years. Among the causes of POI are genetic, metabolic disorders, as well as infectious or iatrogenic factors, but in some cases the exact cause cannot be established. Given the possible association of ovarian failure with autoimmune disorders, as well as the detection of antibodies to normal ovarian tissue in the serum of patients with POI, it is assumed that an autoimmune mechanism is a significant cause of the syndrome. Taking into account the relationship between POI and autoimmune diseases, it seems relevant to address the issues of mutual influence of the ovarian function of women with POI and rheumatic diseases (in particular, systemic lupus erythematosus, rheumatoid arthritis and systemic scleroderma), which is presented in this review. Hormone replacement therapy may be recommended for women with POI to improve their quality of life.
Keywords: premature ovarian insufficiency, menopause, anti-ovarian antibodies, systemic lupus erythematosus, rheumatoid arthritis, systemic scleroderma, rheumatic diseases, hormone replacement therapy.