bluuebunny/crossref_metadata_2025 huggingface dataset:
INFORMATION NEEDS FULFILLMENT OF K-POP FANS THROUGH THE USE OF LYSN SOCIAL MEDIA
Authors: Laiyenes Jesslyn , Utami Lusia Savitri Setyo
Published: October 2023

Technology development eases the process for humans to fulfill information needs by giving birth to new media. One form of new media is social media. Nowadays, to meet humans' information needs, we can use many social media, one of them is Lysn. Lysn is a social media that only provides information about K-Pop. This research aims to describe the fulfilment of K-Pop fans' information needs through the use of Lysn, uses several supporting theories: mass communications, new media, social media, uses and gratifications theory, information needs, and fandom. This research uses a qualitative approach with a case study method. Research data were obtained from observation, in-depth interviews with four informants, documentation, and literature study. This research shows that K-Pop fans get the fulfilment of their information needs through Lysn. Information obtained from Lysn has succeeded in meeting the five needs of audiences in media. In addition, K-Pop fans also expressed their satisfaction with the information obtained from Lysn. Lysn's presence positively impacts the K-Pop fandom because it provides a fun experience and information that cannot be found in other media.
PARENTAL INVOLVEMENT: TEACHERS’ PERCEPTIONS AND THEIR ROLE IN TEACHER WELL-BEING
Authors: Pramanik Ratih , Heng Pamela Hendra , Tiatri Sri
Published: October 2023

The online learning process at the Kindergarten education level prevents direct interaction between teachers and children. The pattern of collaboration between parents and teachers to support the learning process has also changed. However, parental involvement in children's education is not always according to the teacher's expectations. Parental involvement is the participation of parents in the process of their children's educational experience. Teachers can perceive barriers to parental involvement in their children's education. This study aims to examine the role of teachers' perceptions of the barriers to parental involvement on the well-being of Kindergarten teachers. This study uses a non-experimental quantitative method, with purposive sampling technique to find participants who are willing to provide the information needed. The study sample numbered  67 Kindergarten teachers in Tangerang, who are actively teaching during the COVID-19 pandemic. The results show that teachers' perceptions of barriers to parental involvement have a significant role in the well-being of Kindergarten teachers, meaning that if teachers perceive barriers to parental involvement, teacher well-being is affected.
EXPLORING THE SOCIAL CAPITAL ELEMENTS IN PANCASILA
Authors: Walukow Devy Stany , Tirza Juliana , Ratnaya I Gede
Published: October 2023

The difference in the definition of social capital is a matter of academic debate. The six elements of social capital, namely network, interaction, trust, solidarity, tolerance, and norms, will be used as a measuring tool for assessing social capital in Pancasila. This paper uses a literature study to examine BPUPKI's efforts to find solutions for living together and ratify Pancasila as the ideal foundation and establish Pancasila as the constitutional law. Pancasila June 1, 1945, as the ideal foundation contains values, born from the feel and awareness of living together, while Pancasila August 18, 1945, as the constitutional law to the regulations that are binding and coercive as one country. Pancasila was born from agreement and consensus, where the role of fundamental Islamic groups agreed to Pancasila as the basis of the state because of humility for the sake of the country. This process shows the strength of Pancasila as social capital which contains six elements of social capital. But the element of trust has not been able to form social bonds that run well and in the long term. In fact, the belief element is the strength of Pancasila as social capital because religious teachings are about good and bad, as well as "taboo" beliefs about what can and should not be violated as a local genius.
THE RELATIONSHIP BETWEEN OPTIMISM AND SUBJECTIVE WELL-BEING OF YOUNG ADULTS IN THE CONTEXT OF COVID-19 PANDEMIC
Authors: Katim Hanisya Rahmasari , Satiadarma Monty P. , Wati Linda
Published: October 2023

The goal of this study is to test the relationship between optimism and subjective well-being of young adults in the context of COVID-19 pandemic. Throughout the COVID-19 pandemic, numerous studies showed that people’s subjective well-being level have reduced, especially in young adults. This study took one of the factors affecting subjective well-being, optimism as a predictor of people’s subjective well-being throughout the COVID-19 pandemic. Subjective well-being is an individual’s cognitive and affective evaluation of their lives. Optimism is an individual’s positive attitude of their lives and their future. This study involved 338 young adults. The measuring instruments used in this study are: 1) The Revised Life Orientation Test (LOT-R) adapted from Fadjri; 2) The Positive Affect Negative Affect Schedule (PANAS) and Satisfaction with Life Scale (SWLS) are both adapted from the Research and Measurement Department Faculty of Psychology, Universitas Tarumanagara. The analysis result using Pearson correlation technique, with r (338) = 0.251, p = 0.00 (< 0.05) showed that there was a significant and positive correlation between optimism and subjective well-being. This study also found that between the components of optimism and subjective well-being had a significant relationship between the two variables.
THE RELATIONSHIP BETWEEN SOCIAL SUPPORT AND ADJUSTMENT ON FRESH GRADUATES WHO WORK DURING PANDEMIC
Authors: Istari Salsha , Satiadarma Monty P. , Wati Linda
Published: October 2023

Amid the Covid-19 pandemic, this condition requires all levels of society to adapt to the current situation, including fresh graduate students who are also required to adapt to the current conditions. This study aims to determine the relationship between social support and adjustment to fresh graduate students who have just worked during the covid-19 pandemic. The study involved 115 fresh graduates who had just worked during the covid-19 pandemic for at least 6 months, consisting of 42 men and 73 women. Social support variables were measured using the Multidimensional Scale of Perceived Social Support (MSPSS) and self-adjustment variables were measured using The Weinberger Adjustment Inventory. The results of data analysis using the Spearman correlation test technique between social support and adjustment, obtained r (115) = 0.0202, p = 0.031 (< 0.05). The results of the correlation of these two variables indicate that there is a positive and significant relationship between social support and self-adjustment.
The Importance of COSO Framework Compliance in Information Technology Auditing and Enterprise Resource Management
Authors: Oluwaseun Oladeji Olaniyi  , Dagogo Sopriala Omubo
Published: October 2023

This article examines the significance of the COSO framework in managing risks and establishing effective control environments for organizations' IT systems. It delves into the five essential components of both the COSO frameworks for internal control and enterprise resource management. Furthermore, it outlines the principles that define each of the COSO frameworks for internal control and enterprise resource management components and elaborates on their impact on the COSO framework objectives. The authors also shed light on the paramount concerns of an auditor during an IT audit. In conclusion, the article provides several recommendations for integrating COSO framework compliance into an organization's information technology plan. This articles a valuable resource for auditors, administrators, and management seeking to develop an IT strategy that aligns with their business strategy and safeguards their information systems and data.
Effectiveness of Technical Vocational Education and Training (TVET) on Self-Employed Youths for Sustainable Skills Empowerment in a Knowledge-Based Economy in Lagos State, Nigeria
Authors: Dr. Ogunbote Shefiu  , Dr. Dawodu Rasheed Adegbenro  , Dr. Okeowo Rebbeca Oyenike  , Adewuyi Babajide Adetunji
Published: October 2023

Nigeria today is in a depressed economy because the tool that is needed to revamp the economy is being looked down upon, meaning the government of today has lukewarm attitudes towards Technical Vocational Education and Training (TVET), not taking note that the development of any nation is based in her economic, industrial and technological advancement. The study investigates the effectiveness of Technical Vocational Education and Training (TVET) on self-employed youths for sustainable skills empowerment in a knowledge-based economy in Lagos State. The study adopted a descriptive survey method. The population of the study was 60 students (30 undergraduates and 30 postgraduates, respectively). 60 questionnaire items were used, but 58 were retrieved, comprising 32 undergraduate and 26 postgraduate students. One research question and one hypothesis guided the study. The paper identifies the effectiveness of TVET and factors that inhibit its relevance on self-employed youths for sustainable skills empowerment in a knowledge-based economy. The study concluded, among others, that government and other stakeholders must provide an enabling environment for quality instructional delivery and TVET should be given utmost priority, having in mind the future consequences and the task ahead for sustainable youth skill empowerment in a knowledge-based economy, among others.
Evaluation of Computational Analysis for Stiffened Slab Using Finite Strip Method
Authors: V. Ike  , I. S. Akosubo  , V. T. Ibeabuchi
Published: October 2023

A rectangular slab stiffened by ribs oriented perpendicular to the support of the slab as structurally equivalent to an orthotropic plate has been analyzed using the finite strip method. The analytic formulation was obtained from the governing equation of motion of the plate using the classical plate theory to an arbitrary boundary and initial condition. The stiffness formulation from total internal energy was considered. The force-displacement equation technique by applying stiffness and uniformly distributed loading was used to obtain the modal solution and hence, displacement at an arbitrary point of the plate for the assumed harmonic function. Approximate stresses following the displacement are also obtained. The comparative solution of the equilibrium differential equation is obtained by means of convergent series expansions of levy plates and the application of Timoshenko and Woinowsky-Krieger averaging of bending rigidity, utilizing suitable orthogonal displacement functions. A computer procedure based on the finite strip method is given through the application of numerical examples, which shows that the procedure provides good results, especially with low discretization and computational effort.
An Appraisal of Legal and Institutional Framework Regulating Tax Collection in Nigeria
Authors: Agwor Charles I.G.  , Chinwe Bekwele Wami
Published: October 2023

This research focused on exploring the regulatory framework governing tax collection in Nigeria, with a specific emphasis on the legal and institutional aspects. The analysis involved examining the relevant provisions of the Constitution of the Federal Republic of Nigeria 1999 (as amended) related to taxes and associated matters. Key statutes that regulate taxes and taxation were also scrutinized, including the Federal Inland Revenue Service (Establishment) Act, the Personal Income Tax Act, the Companies Income Tax Act, the Capital Gains Tax Act, the Value Added Tax Act, the Stamp Duties Act, and the Taxes and Levies (approved List) Act. Furthermore, the study investigated the governmental agencies responsible for tax collection and administration, such as the Federal Inland Revenue Service (FIRS), the Joint Tax Board (JTB), the Federal Board Inland Revenue (FBIR), States Board of Internal Revenue (SBIR), Local Government Revenue Committees, and Joint State Revenue Committees. The research paper was concluded by providing a summary of the findings.
Public Investment in Social Services and Income Inequality in Nigeria
Authors: Sigah, Donny Marclary Ayibazuomuno  , Yousuo Purumaziba John O.
Published: October 2023

This study contributes to the body of knowledge by investigating the dynamic effects of public social services investment on income inequality in Nigeria. The motivation for this study is the controversy surrounding the effectiveness of public spending on social services in promoting economic development in developing economies. Thus, this study followed an ex-post factor research design by obtaining annual time series data from the CBN Statistical Bulletin and the National Bureau of Statistics, which were analysed with the application of the autoregressive distributed lag (ARDL) model. Evidence of mixed integration was established from the unit root test results. The series was also found to be co-integrated at the significance level of 5 percent. It was established from the findings that public spending on social services significantly reduced income inequality in the long run. This finding explains the effectiveness of social services spending in income redistribution in the long term. The results also showed that public expenditure on economic services reduced income inequality in the short run. However, total public expenditure, as a percentage of the GDP, has a negative but insignificant effect on income inequality in the long run. This finding casts doubt on the effectiveness of total public expenditure in addressing the problem of income inequality in Nigeria. Given the findings, this paper recommends that policymakers should provide a sustainable path for increased public investments in social services to the required vehicle for equitable income distribution in Nigeria.
Determinants of Inventory Holdings in Listed Brewery Firms in Nigeria
Authors: Nnado Ifeanyi Celestine  , Ugwu Collins Chukwuma
Published: October 2023

The study empirically assessed the firm-specific and macro-economic factors influencing investments in inventories in quoted firms of the Nigerian Brewery sub-sector. This became imperative as these firms are the only ones that have not divested to much more conducive nearby economies such as Ghana, South Africa, Egypt, etc. It adopted the ex post facto research design as secondary data were used. It spanned an 11-year period (i.e., 2011 to 2021). Diagnostic tests carried out indicated the absence of both unit roots and heteroskedasticity. Panel least squares regression analysis (Prais-Winsten regression, correlated panels corrected standard errors) showcased the statistical relevance of these associations. Except for inflation (a macroeconomic variable), the remaining predictors exerted very strong influences on investment in inventories to total sales. Brewery firms' profits are highly influenced by such macro-economic variables as interest and exchange rates, given that bulk of raw materials are sourced from overseas. Given a negative relationship between the cash conversion cycle, firms should always try to limit the time between sales and collection of advanced credits to enhance investment in inventories and earnings. Managers should manage their working capital in more efficient ways by reducing the number of days inventories are held to an optimal level in order to enhance their profitability as well as create value for their shareholders.
Women’s Entrepreneurial Competencies and Economic Development: A Review of Literature
Authors: John-Eke, Ebere Chika  , Gabriel, Justin Mgbechi Odinioha
Published: October 2023

The success or failure of entrepreneurs has so much to do with the economic development, growth or lack of it in any nation. As a review paper, relevant scholarly views were put to the rigorous test of thoughts and comparisons. The key observations and extrapolations revealed that women entrepreneurs contribute significantly to Nigerian economic development through wealth creation, poverty eradication, employment generation, and basic family support, among others. Several challenges were also observed as delimiting the potential of women entrepreneurs in Nigeria, especially the issues of gender inequality, lack of access to finance, inability to gain stakeholders' confidence, technological illiteracy and decrepit infrastructure, among others. The paper concluded that entrepreneurship remains the shortest road to economic liberation for any nation and efforts must be put in place to develop and harness its tenets for the benefit of all, male and female alike. Drawing from the avalanche of reviews, we, therefore, recommend that:

Government should create more enablers for women entrepreneurs, ranging from training, improved financing, favourable policies and direct supervisory support,

Women entrepreneurs should personally upscale their basic business management skills, increase their self-efficacy and boldly take opportunities like their male counterparts or even more.
Strategic Flexibility and Employee Productivity of Quoted Pharmaceutical Companies in Nigeria
Authors: Adeleke, Adedeji Abraham  , Ajike, Emmanuel Ogbonna  , Nwankwere, Idowu Aderonke  , Bamidele, Ayodeji Gbenga
Published: October 2023

The global pharmaceutical industry is becoming increasingly prone to disruptions and economic fluctuations. In Nigeria, available records showed that pharmaceutical companies are plagued with poor employee productivity in the face of increasing competition and changes in the business environment. This study investigated the effect of strategic flexibility on employee productivity of quoted pharmaceutical companies in Nigeria.

The survey research design was adopted for the study. The research population consisted of 642 management and senior staff employees of the six quoted pharmaceutical companies in Nigeria. The study adopted total enumeration in soliciting responses from the sample population using an adapted and well-structured questionnaire. The data collected from respondents were analyzed using both descriptive and inferential (PLS-SEM) statistics.

Findings showed that strategic flexibility (coordination flexibility, futurity, reactive flexibility, resource flexibility) has a positive significant effect on employee productivity of quoted pharmaceutical companies in Nigeria. The study concluded that strategic flexibility does have a positive impact on employee productivity of quoted pharmaceutical firms in Nigeria and recommended that management of the pharmaceutical companies should pay more attention to resource flexibility, coordination flexibility, reactive flexibility and futurity in their bid to enhance employee productivity.
The Role of Intrapreneurship in Growing SMEs: A Narrative Review
Authors: Ioana Alexandra Onea
Published: October 2023

Nowadays, innovation is of the utmost importance for organizations because it facilitates the path towards competitive advantage and economic growth. This is particularly true for small and medium enterprises, meaning companies that have limited financial support and resources. Entrepreneurship is a concept frequently associated with innovation as it involves ambitious individuals willing to outpace their comfort zone and take risks. However, intrapreneurship is another concept that, although similar to entrepreneurship, embodies several differences, which are important while considering the connection with innovation. Intrapreneurship or corporate entrepreneurship is a term that is progressively associated with innovation. It refers to individuals who are motivated to drive transformation and are willing to change the status quo. The purpose of this paper is to depict the current level of knowledge regarding the impact of intrapreneurship on innovation and to understand the major trends with reference to the existing theory. Therefore, we have conducted a narrative literature review to obtain an in-depth understanding of the research topic and provide recommendations for managers and practitioners who activate in small and medium enterprises. The findings show that intrapreneurship has a positive effect on innovation and individual traits, and the organizational environment has an extensive influence on intrapreneurial behavior.
Soft Skills Training Program as a Moderator on the Relationship between Entrepreneurial Orientation and Channel Performance
Authors: Dr. Loo Yew Liang
Published: October 2023

This study focuses on soft skills training program whereby soft skills refer to a person's ability to relate with others as well as with one's own self (Nayak, 2014). Soft skills are often studied and discussed compared to hard skills of an individual to resolve some technical problem or liaise with intellectual challenges based on their knowledge and ability. The purpose of this paper is to explore the moderating effects of soft skills training program on the relationship between entrepreneurial orientation (proactiveness, innovativeness, and risk-taking) and channel performance. Soft skills training programs can have a positive impact on entrepreneurship and help to increase channel performance in a number of ways. The methodology of the study was guided most generally by positivist research in using precise, objective measures and is usually associated with quantitative data (Cavana, Delahaye, & Sekaran, 2000). A sample of 320 top-ranked MLM sales agents across the Multi-Level Marketing (MLM) industry in Malaysia was selected to participate in this structured questionnaire. Hierarchical regression analysis is used to test the moderating effect of soft skills training program on the relationship between entrepreneurial orientation and channel performance. The findings showed that soft skills training program moderates each of these relationships, which are proactiveness and innovativeness, whereas risk-taking showed the negative impact on channel performance with a moderator effect. This study gives new exploration in MLM industry of Malaysia whereby soft skills training program as a moderator delivers some significant relationship between entrepreneurial orientation and channel performance.
Role of Employability and Life Skills in Securing and Retaining Livelihood Opportunities
Authors: Dennis Gichobi Muchiri
Published: October 2023

In today's workplace, a blend of both hard and soft skills is needed for employees to succeed, even though the latter remains overlooked. Hard skills are the job-specific abilities that workers need to perform their duties, while soft skills are the personal qualities they need to thrive in the world of work. This study postulates that learning institutions have overly inclined towards hard skills at the expense of soft 'employability' skills, thereby making those seeking to secure or progress in their jobs learn the hard way their need for such skills. The objectives were:

To study the most important factors that organizations consider while hiring or promoting workers,

To observe the common employability and life skills that employers consider while making hiring/promotion decisions, and

To assess the extent to which employability and life skills are important in securing and maintaining livelihood opportunities.

With the research seeking to answer the 'what' question rather than the 'how' or 'why,' a descriptive research design was adopted to complement an inductive reasoning approach. A mixed methodology was used to collect quantitative and qualitative data from 284 respondents from 24 counties in Kenya out of 47, who represented more than 10 sectors. The results show that employability skills constitute the main factor of consideration while hiring/promoting workers. The common employability skills include communication, time management, a positive attitude, teamwork, and decision-making. Without these soft skills, workers struggle to secure and maintain jobs at the strategic, business, and operation levels of an organization.
Effects of Short Story Reading on EFL Narrative Writing
Authors: Bui Thanh Minh Quang
Published: October 2023

This study examined the effects of short story reading on the improvement of grammar and global quality in EFL narrative writing. In addition, it also explored learners' attitudes toward short story reading on narrative writing performance. The 7-week study was carried out at a university in Mekong Delta, Vietnam, with 50 EFL learners at the pre-intermediate level. Participants were chosen and divided into an experimental group with the intervention of short story reading and a control group with course book reading. Two types of research instruments were used to collect quantitative data, including tests and survey questionnaires. Results showed that short story reading had positive effects on the improvement of grammar and global quality in EFL narrative writing. Moreover, the findings also showed the positive attitudes of EFL learners toward short story reading on narrative writing performance.
Assessing the Pedagogical Content Knowledge of Social Studies Teachers in Schools within the Accra Metropolis
Authors: Oti Richard  , Issaka Rafiu
Published: October 2023

This study assesses the pedagogical content knowledge of Senior High School Social Studies teachers in the Accra Metropolis, Ghana. A sample size of 86 teachers was chosen using a multi-stage (purposive, convenience) sampling approach. Questionnaires and semi-structured interview guides were the primary data-gathering tools. The study's findings revealed that a substantial number of teachers met the minimum academic qualification for teaching social studies at the Senior High School level in Ghana, with the majority of teachers holding a B. Ed/BA in Social Studies. Again, the majority of instructors believed that their academic experience influenced their social studies teaching. The study recommends that the Ghana Education Service should only recruit teachers with the required academic background in social studies to teach the subject. Also, the teachers without the required academic background should be taken through in-service training to provide them with the appropriate social studies Pedagogical Content Knowledge.
Seasonal Changes of N-Alkanes in Water and Suspended Particulate Matter from Cross River Estuary, South-east Nigeria
Authors: Patience Y. Nkom  , Inyang O. Oyo-Ita  , Samuel U. Ugim  , Orok E. Oyo-Ita
Published: October 2023

Several studies worldwide have attributed the seasonal variation in aromatic compound levels to changes in riverine discharges and rainfall, yet similar correspondence with n-alkanes distributions is scarcely undertaken. Assessment of the behavior of n-alkanes in water and suspended particulate matter from Cross River estuary, South-South Nigeria, with depth in reaction to anthropogenic pressure/hydrological cycles and their source contributions were carried out by gas chromatography–flame ionization detector. Higher mean levels of n-alkanes in water and suspended particulate matter were recorded in the wet season than in the dry season, linked to the effects of higher wet precipitation and surface run-off as well as proximity to point sources where anthropogenic activities were at the peak of the rainy season. Evaluation of diagnostic indices values such as long-chain hydrocarbon/short-chain hydrocarbon, terrestrial aquatic ratio, carbon preference index, carbon maximum, proxy aquatic ratio, n-alkanes/C16 and unresolved complex mixture as well as multi-variate statistics [eg. Multiple linear regression and principal component analysis] revealed that vascular plant/wood combustion predominated with moderate-to-minor contributions from macrophytes, degraded oil, petrochemicals and algae/photosynthetic bacteria. Changes in hydrological parameters, including suspended sediment concentration, temperature, salinity, and anthropogenic pressure, influenced n-alkanes distribution in the estuary.
Iperu U’komanto: Árvore da Vida
Authors: Silva Maria Georgina dos Santos Pinho e
Published: October 2023

Três irmãos, um animal e uma árvore que produz diferentes tipos de frutos. A história gira em torno do lendário Makunaima, que compõe o mundo indígena de maneira criativa, sobrenatural e real. As aventuras de Makunaima estão no livro Iperu U’komanto: mito indígena, ilustrado pela artista plástica Carmen Silva, que enrique esta primeira edição com o carinho de quem faz uma obra de arte com devoção. As filigranas de vozes que repercutem na história vêm do lavrado, dos antepassados que transcendem gerações, demonstrando a riqueza da cultura indígena.
Titanium dioxide Ag NP enhanced solid solar cell electrodes for favourable efficiency
Authors: Njoroge David K.
Published: October 2023

Population growth leads to a heightened demand for working potential to support modern commercial and residential evolutions. Available conventional energy sources, however, cause environmental pollution and severe health problems like global warming. The current energy sources also face challenges due to factors like global warming that make hydro-generated energy production even more difficult due to droughts. Therefore, alternative energy options need to be explored. The study in question aimed to find a cost-effective and environmentally friendly energy source by fabricating a solar cell that uses titanium dioxide and potassium iodate (mixed in carbon) layers in a solidified structure. TiO2 was chosen due to its photo-generating properties and synthetic steadiness over a spread acidity/basicity neutrality. The iodine/iodide complex was used to replenish the photo-excited electrons while graphite facilitated their migration. The researchers varied the ingredients capacities for the separate electrodes keeping the rest unvaried for improved (I-V) terminal parameters. Deduction from the research established that the (0.4:0.3:0.17:0.01) TiO2/CX:I2:KI proportions resulted in the optimum charge range generation. The inclusion of potassium iodate (KI) improved iodine solvability and facilitated even dispersal in graphite, which was maintained at 0.01 g in all cells. The absorber and receptive layer thicknesses of 2.00 mm and 1.00 mm respectively generated the best 0.979 V open-circuit voltage (Voc) and 12.037 μA short-circuit current (Isc) results. Favorable (10.46%) efficiency (η) and (0.64) fill factor (FF) were derived. Conducting transparent glass was suggested for improving the linkage to the external circuit and models of reducing air pockets in the solid TiO2 photovoltaic devices could further enhance their performance.
Analisis Faktor-Faktor Yang Mempengaruhi Konsumsi Daging Ayam Ras Di Kecamatan Teluk Ambon Kota Ambon
Authors: Matatula M J , Kewilaa A
Published: October 2023

Increasing people's welfare is in line with increasing consumption of broiler meat as a source of animal protein. Improving a person's quality of life has implications for a selective attitude in choosing the quality and quantity of food consumed. This study aims to analyze the factors that influence the consumption of purebred chicken in Teluk Ambon District. The research location was determined purposively, namely deliberately in the market located in Teluk Ambon District, namely Pasar Rumah Tiga and Pasar Wayame. The basis for location considerations is that the people around the market have varied occupational professions and have heterogeneous levels of education. The research sample was drawn using the accidental sampling method, namely taking samples of respondents who are consumers who happen to shop for chicken meat. Respondents were taken as many as 60 people. To analyze the factors that influence the amount of consumption of chicken meat analyzed using multiple linear regression analysis method. The research results show that the price of chicken meat, the price of chicken eggs, the price of fish, the level of education, dependants, tastes, and income together have a significant influence on the amount of consumption of chicken meat. Partially, the variable price of chicken meat, the number of family dependents, income tastes have a significant effect on the amount of chicken meat consumption, while the price of chicken eggs, the price of fish, and the level of education have no significant effect on the amount of chicken meat consumption.
The Potential of Natural Stabilizer of Uwi Starch to Improve The Quality of Set Yoghurt Goats Milk during Self Life
Authors: Usman N A , Riffiandi N
Published: October 2023

Processing goat's milk into yoghurt products can reduce the distinctive aroma of 'prengus' by adding a starter that will break down lactose into lactic acid and switch the milk smell into a distinctive odour of yoghurt. It will also increase the consumption of goat's milk with higher nutritional value and extend the shelf life. This study aims to determine the potential of the natural stabilizer of uwi starch in improving the quality of set yoghurt goat's milk during its shelf-life. This study was conducted in experimental used CRD with four treatments (P1: 0-day storage, P2: 2 days storage, P3: 4 days storage, P4: 6 days storage) and five replications. Analysis of variance used to determine the potential of the natural stabilizer of uwi starch on total lactic acid bacteria, viscosity, and water content set yoghurt goat's milk. And then, Honestly Significant Difference was used to know the difference between the treatments. The results showed that the treatment adding a natural stabilizer of uwi starch was significantly different (P<0.05) in total lactic acid bacteria during storage and had no significant effect (P>0.05) on viscosity and water content during storage
Relationships Between Common Preseason Screening Measures and Dance-Related Injuries in Preprofessional Ballet Dancers
Authors: Critchley Meghan L. , Bonfield Stephan , Ferber Reed , Pasanen Kati , Kenny Sarah J.
Published: October 2023

OBJECTIVE: To examine modifiable and nonmodifiable factors for associations with dance-related injury among preprofessional ballet dancers over 5 academic years.

DESIGN: Prospective cohort study.

METHODS: Full-time preprofessional ballet dancers (n = 452; 399 female; median age [range], 15 years [11-21]) participated across 5 academic years at a vocational school. Participants completed baseline screening and online weekly injury questionnaires including dance exposure (hours/week). Zero-inflated Poisson regression models were used to examine associations between potential risk factors measured at baseline and self-reported dance-related injury.

RESULTS: In count model coefficients, left one leg standing score (log coefficient estimate, −0.249 [95% CI: −0.478, −0.02]; P = .033) and right unipedal dynamic balance time (log coefficient estimate, −0.0294 [95% CI: −0.048, −0.01]; P>.001) carried a protective effect with increased years of training when adjusted for Athletic Coping Skills Inventory (ACSI) score. A significant association was found for left unipedal dynamic balance time and dance-related injury (log coefficient estimate, 0.013 [95% CI: 0.000, 0.026]; P = .045) when adjusted for years of training and ACSI score. There were no significant associations between dance-related injury and ankle and hip range of motion, active straight leg raise, or Y Balance Test measures.

CONCLUSION: When adjusted for years of previous dance training and psychological coping skills, there was a significant association between limb-specific lumbopelvic control and dynamic balance tasks, as well as self-reported dance-related injury in preprofessional ballet. J Orthop Sports Phys Ther 2023;53(11):703-711. Epub 3 October 2023. doi:10.2519/jospt.2023.11835
Perbandingan Efisiensi Inhibitor Organik dan Anorganik pada Penurunan Laju Korosi Material Radiator
Authors: Hastuti Kurnia , Argak Dwi Wandana  , Yulianto Dody , Dedikarni  , Rahman Jhonni , Anwar Irwan
Published: October 2023

Radiator adalah suatu sistem atau komponen yang berfungsi utuk menjaga supaya temperatur mesin dalam kondisi ideal. Inhibitor anorganik telah terbukti dapat menurunkan laju korosi namun memiliki efek negatif karena materialnya yang tidak ramah lingkungan dan bersifat racun. Berdasarkan hal tersebut maka penggunaan inhibitor anorganik perlu dibatasi. Pada penelitian ini akan dibandingkan efisiensi inhibitor organik dan anorganik dalam menurunkan laju korosi. Inhibitor anorganik yang digunakan adalah Natrium Kromat (Na2CrO4) dengan konsentrasi 0,5%, 0,7%, dan 0,9%. Sedangkan inhibitor organik adalah Minyak Biji Kapas dengan variasi konsentrasi yaitu 25%, 30% dan 35% dalam  waktu perendaman 21 hari dalam setiap inhibitor. Selanjutnya akan diuji ketahanan korosinya dengan media air biasa. Hasil pengujian  laju korosi  natrium kromat terendah pada konsentrasi 0,9% dengan nilai 0,0815 mm/y (0,628%) dengan waktu 21 hari. Laju korosi terendah pada konsentrasi 25% dengan nilai 0,1614 mm/y (0,273%). Penelitian ini menunjukan efisiensi perbandingan terbaik masih di lihat pada inhibitor anorganik natrium kromat, setaiap konsentrasi laju korosi semakin rendah.
The Analysis Static of Chassis Robot Arm as Design Modification Induction Melting Furnace Machine Using FEA Method
Authors: Eka Bima Saputra  , Ahmad Zohari  , Andriansyah  , Wahyu Bambang Sulistyo
Published: October 2023

Induction furnace is a metal melting furnace that uses heater. The high temperatures can cause work accidents if not carefully. The cause of work accidents, especially machines is had mistake when initially machine designed. An alternative solution is to make improvements the machine. The researcher made a robot arm design that functions to transfer melting products and reduce work accidents like being exposed to melted metal. The researcher’s purpose is to analyze the design static of  robot arm as modification induction melting furnace machine. The method is to study previous research literature related to static simulation. Researchers use the SolidWork premium 2018 software which consists of stress (von mises), displacement, and FOS (factor of safety) calculations. Based on the static simulation results, it can be concluded that the highest values ​​of simulated stress (von mises) at 5N, 10N, and 15N loads were 13.926Mpa, 27.728Mpa, and 41.531Mpa which categorized as feasible because they were below yield strength value of 64.205Mpa. Simulation displacement, the design experienced the most significant deformation at 15N load with value of 0.337 mm. The FOS (factor of safety) value each loading were 4.610; 2.315; and 1.474 which fulfills the static load safety requirement 1.25.
Discovery of small molecule modulators targeting β-catenin interactions using molecular docking and molecular dynamics strategy
Authors: Veerappapillai Shanthi , Hussain Aman
Published: October 2023

The rapid activation of signaling pathways is the primary factor responsible for the progression of serious malignancies. Particularly, overexpression of β-catenin is one of the preventative oncogenic biomarkers that is widely present in many tumor types. Therefore, we have designed an integrated pharmacophore strategy to discover the potential inhibitor against β-catenin. Primarily, the ligand-, energy-optimized and the receptor cavity-based pharmacophore hypothesis AAHHR, ADR and ANNNRRR were constructed to screen the active molecules from the database. In order to improve the screening efficacy, the resultant molecules were scrutinized by integrating the results obtained through docking and MM/GBSA calculations. Further, the common hit molecules were subjected to a pharmacokinetic and toxicity study which resulted in two potent β-catenin inhibitors: BAS03014832 and BAS01077671. The existence of thiazole and pyrazole moiety is responsible for the anti-neoplastic activity of these molecules. Finally, a deep neural network technique was used to assess the inhibitory action of these compounds across 66 colorectal cancer cell lines. Overall, the results of our study portray a pathway for the experimental biologist in developing selective β-catenin inhibitors.
Molecular modeling study combined with deep learning approach for the identification of potent β-catenin inhibitors
Authors: Veerappapillai Shanthi , Tandon Shikhar
Published: October 2023

β-catenin is a propitious target for various cancer drugs for inhibiting tumour cell proliferation and differentiation. Even though several inhibitors have been discovered for β-catenin but its selectivity towards β-catenin and TCF-4 interactions is a major challenge. Hence, the expedition for identifying a selective drug for β-catenin inhibition against cancer will have immense potential and favour. The present study aims to scrutinise compounds that can impede β-catenin overexpression in cancer using an integrated pharmacophore and in silico docking-based screening of 28,007 molecules from the ZINC repository. The analysis yielded the top two compounds, namely ZINC000016051423 and ZINC000028564770, with better docking scores of -4.007 kcal/mol and -6.547 kcal/mol at the β-catenin binding pocket. Moreover, their free energy scores were -40.882 and -53.989 kcal/mol with favourable drug-likeness characteristics. Eventually, both hits exhibited better inhibitory activity against 66 colorectal cell lines using the PaccMann algorithm. In conclusion, our findings suggest that the lead compounds may serve as a possible β-catenin inhibitor during the treatment of cancer, though further experimental study is needed to evaluate the compound’s efficacy.
Screening Streptomyces secondary metabolites against non-small cell lung cancer using computational approaches
Authors: Vijayasarathy Sampath Kumar , Akila Swaminathan , Rangasamy Nithin Pranao Senthilkumar , Veerappapillai Shanthi
Published: October 2023

Secondary metabolites from bacterial sources are being seen as alternatives to identify new medicines for various disease conditions. Streptomyces is known to be a warehouse of secondary metabolites and is a promising source to be looked for the discovery and development of new anti-tumorigenic agents. Such identifications could alleviate the issue of lung cancer that takes over 2 million lives a year. In the current study, we have screened secondary metabolites from Streptomyces for their potential to act as drugs for non-small cell lung cancer. The metabolites were identified for their ability to inhibit RET protein. Gene fusion partners cause alteration to the RET protein that causes the cancer condition. The metabolites identified were based on docking, pharmacokinetics, toxicity and pass prediction. 16 metabolites from 13 different species of Streptomyces showed binding affinity to the target protein. Among the metabolites, melanin was the one that had strongest evident to act as a drug candidate for non-small cell lung cancer therapeutics.
Exploring the antibacterial effects of Ocimum sanctum (O. sanctum) silver nanoparticles
Authors: Reshma K. , Rahul Amin Sheikh , Jemima Aashmi P.L. , Vishnudas D. , Danie Kingsley J.
Published: October 2023

The current study was undertaken to provide sustainable solutions to Erythromycin-resistant bacterial strains. Silver nanoparticles were produced using an environmentally friendly green synthesis process using Ocimum sanctum leaf extract. The synthesized Ocimum sanctum leaf extract silver nanoparticles were then examined using a variety of methods. In the UV-Vis spectrophotometer, the peak was observed at 398nm. Scanning electron microscopy (SEM) revealed the size of the nanoparticles to be between 24-44nm. The crystalline size of AgNPs was determined to be 12.02nm by X-ray diffraction (XRD) and Fourier transform infrared (FTIR) spectroscopy revealed the presence of functional groups like alcohols, phenols and carbonyl groups which provide better interaction and stability of the nanoparticles. Bioactive compounds of Ocimum sanctum leaves were found to be effective against both Gram-positive and Gram-negative bacterial strains as nanoparticles which is evident by having no inhibition against Bacillus Subtilis and E. coli in lower concentrations of 30μl and 50μl. On the other hand, Ocimum sanctum leaf extract AgNPs had a positive dose-dependent inhibition against all the strains. The Ocimum sanctum silver nanoparticles were effective against E. coli (Gram-negative), Staphylococcus aureus (1.9cm), Streptococcus mutans (1.7cm) and Bacillus Subtilis (Gram-positive). Thus, Ocimum sanctum Silver Nanoparticle-based drug delivery has proven to be an effective anti-bacterial treatment worth exploring specifically against Erythromycin-resistant strains.
Streptomyces sp. VITGV156 (MCC 4965), a quinoline producing Streptomyces
Authors: Hussain Amjad , Godwin Christopher J.
Published: October 2023

The genus Streptomyces is renowned for its ability to synthesize a wide range of secondary metabolites, encompassing antimicrobial, anticancer, antiviral, antioxidant, immunosuppressant and antimalarial properties. In this study, we focused on Streptomyces sp. VITGV156 to explore its potential in producing quinoline, a secondary metabolite, leveraging the species' extensive biosynthetic gene repertoire. The complete genome of Streptomyces sp. VITGV156 was sequenced using Illumina technology and NextSeq. Genome analysis unveiled 29 Biosynthetic Gene Clusters (BGCs), including 7 PKS (Polyketide Synthases) and 5 terpenes, responsible for secondary metabolite production. The crude extract of VITGV156 was subjected to GC-MS analysis, revealing the presence of 30 distinct compounds, 15 of which exhibited antimicrobial activity. Notably, quinoline carboxylic acid was detected at a retention time of 17.628 min. Given the promising antimicrobial activity displayed by the crude extract of Streptomyces sp. VITGV156, further investigations are planned to gain deeper insights into its secondary metabolites.
Biodegradation of LDPE (low density polyethylene) using bacterial strain
Authors: Suresh Anushree , Sharma Jayati , Kumar Aardra V. , Raj Amal , Abraham Jayanthi
Published: October 2023

The applications of polyethylene are enormous and they are popular because of their relatively low cost, lack of difficulty in manufacture, adaptability and durability. In the past decade, the increase in the utilization of plastics and the accumulation of polyethylene in the environment all around the globe has drawn the attention of environmentalists and scientists. The plastic materials are commonly derived from petrochemicals extracted from coal and natural gas. They are produced in a wide range in synthetic, semi synthetic organic polymers. The degradation of LDPE film was determined by residual dry weight loss of the LDPE films. The potent strain showed 42.5% degradation ability in 90 d. Degradation of LDPE results in the breakdown of the polymer backbone chain producing CO2 which was checked by gravimetric analysis. Enzyme kinetic studies showed the production of three ligninolytic extracellular enzymes- lignin, laccase and manganese peroxidase by bacterial strain AJ01 in LDPE degradation. Degradation of LDPE strips followed first order kinetics model with a rate constant (R2) of 0.9783 d-1. Estimation of protein from post treated LDPE using bacterial isolate showed a total concentration of 0.440mg/0.1mL and 0.703mg/0.2mL. LDPE degradation was confirmed by using analytical techniques such as SEM which showed changes in the surface topology of LDPE strips and FTIR analysis showed changes in complex chemical structure of LDPE post 90 d of degradation using microorganisms thereby reducing carbonyl index (CI) value.
Altered Circadian Rhythm of genes involved in Human Senescence: An Interactome Analysis
Authors: Aich Adrija , Kumar Ashish , Thirumurugan Kavitha
Published: October 2023

Genes related to human senescence were explored to find their interaction with Circadian rhythm using Cytoscape. Upregulated genes were analyzed for functional enrichment. In Cytohubba, top 10 ranking genes were scored for attributes like MCC, degree etc. TP53 was identified as a top-ranking gene in these attributes. The cancer network was retrieved in Network analyzer of Cytohubba and merged with TP53 network. The merged network was queried for ‘cisplatin’ using STICH in Cytoscape. Enrichment analysis of cisplatin bound TP53 network showed GO process cellular response to abiotic stimulus, negative regulation of telomere capping, replicative senescence, regulation of reactive oxygen species and cellular senescence.