bluuebunny/crossref_metadata_2025 huggingface dataset:
Development and validation of a prognostic model for assessing long COVID risk following Omicron wave—a large population-based cohort study
Authors: Fang Lu-Cheng , Ming Xiao-Ping , Cai Wan-Yue , Hu Yi-Fan , Hao Bin , Wu Jiang-Hao , Tuohuti Aikebaier , Chen Xiong
Published: May 2024

Background

Long coronavirus disease (COVID) after COVID-19 infection is continuously threatening the health of people all over the world. Early prediction of the risk of Long COVID in hospitalized patients will help clinical management of COVID-19, but there is still no reliable and effective prediction model.

Methods

A total of 1905 hospitalized patients with COVID-19 infection were included in this study, and their Long COVID status was followed up 4–8 weeks after discharge. Univariable and multivariable logistic regression analysis were used to determine the risk factors for Long COVID. Patients were randomly divided into a training cohort (70%) and a validation cohort (30%), and factors for constructing the model were screened using Lasso regression in the training cohort. Visualize the Long COVID risk prediction model using nomogram. Evaluate the performance of the model in the training and validation cohort using the area under the curve (AUC), calibration curve, and decision curve analysis (DCA).

Results

A total of 657 patients (34.5%) reported that they had symptoms of long COVID. The most common symptoms were fatigue or muscle weakness (16.8%), followed by sleep difficulties (11.1%) and cough (9.5%). The risk prediction nomogram of age, diabetes, chronic kidney disease, vaccination status, procalcitonin, leukocytes, lymphocytes, interleukin-6 and D-dimer were included for early identification of high-risk patients with Long COVID. AUCs of the model in the training cohort and validation cohort are 0.762 and 0.713, respectively, demonstrating relatively high discrimination of the model. The calibration curve further substantiated the proximity of the nomogram’s predicted outcomes to the ideal curve, the consistency between the predicted outcomes and the actual outcomes, and the potential benefits for all patients as indicated by DCA. This observation was further validated in the validation cohort.

Conclusions

We established a nomogram model to predict the long COVID risk of hospitalized patients with COVID-19, and proved its relatively good predictive performance. This model is helpful for the clinical management of long COVID.
A survey of cancer patients’ interest in undertaking exercise to promote relaxation during radiotherapy for breast cancer and metastatic cancer
Authors: Moser Rebecca , Mayr Nina A. , Nano Jana , Behzadi Sophie T. , Kiesl Sophia , Combs Stephanie E. , Borm Kai J.
Published: May 2024

Background

Approximately 25–50% of patients undergoing radiotherapy (RT) experience psychological distress and anxiety, which can detrimentally affect both their quality of life and treatment outcomes. While previous research has demonstrated that relaxation exercises can enhance the tolerability of RT and alleviate associated stress and anxiety, the specific needs for such therapies in radiation oncology remain under-explored. This study aims to investigate the demand for and preferences toward relaxation exercises among radiotherapy patients, addressing a critical gap in patient-centered care.

Methods

A prospective pseudonymized survey study using a one-time paper-based questionnaire was conducted from 2022 to 2023 among patients undergoing curative-intent RT for breast cancer or patients undergoing palliative RT for bone metastases. Patients were asked in a 11-item questionnaire about their anxiety, pre-existing practice of relaxation exercises/interventions, their interest in relaxation exercises, and preferences on the type and format of instruction. Data were analyzed descriptively.

Results

100 patients (74 female and 26 male) responded, of whom 68 received curative-intent adjuvant RT and 32 palliative RT. Median age was 62 years. 78% of patients indicated a desire to be actively involved in their radiotherapy, but only 27% had used relaxation exercises prior to RT. 44.8% of both curatively and palliatively treated patients who wanted to be actively involved in their therapy desired to learn how to best relax. 56.4% of respondents were willing to spend extra time learning offered exercises.

Conclusion

The survey indicates that patients undergoing RT, both for curative or palliative intent, desire relaxation exercises to relieve stress and anxiety from RT. It is therefore important to assess the need for relaxation interventions in individual patients and to develop suitable programs or collaborate with other healthcare professionals to meet these needs.
How is postoperative pain after hip and knee replacement managed? An analysis of two large hospitals in Australia
Authors: Ferreira Giovanni E. , Patanwala Asad E. , Turton Hannah , Langford Aili V. , Harris Ian A. , Maher Chris G. , McLachlan Andrew J. , Glare Paul , Lin Chung-Wei Christine
Published: May 2024

Background

Multimodal analgesia regimens are recommended for the postoperative period after hip and knee replacement surgeries. However, there are no data on practice patterns for analgesic use in the immediate postoperative period after hip and knee replacements in Australia.

Objectives

To describe analgesic prescribing patterns in the inpatient postoperative phase for patients undergoing hip and knee replacement.

Methods

Retrospective study of electronic medical record data from two major hospitals in Sydney, Australia. We identified analgesic medication prescriptions for all patients aged 18 years and older who underwent hip or knee replacement surgery in 2019. We extracted data on pain medications prescribed while in the ward up until discharge. These were grouped into distinct categories based on the Anatomical Therapeutic Chemical classification. We described the frequency (%) of pain medications used by category and computed the average oral morphine equivalent daily dose (OMEDD) during hospitalisation.

Results

We identified 1282 surgeries in 1225 patients. Patients had a mean (SD) age of 69 (11.8) years; most (57.1%) were female. Over 99% of patients were prescribed opioid analgesics and paracetamol during their hospital stay. Most patients (61.4%) were managed with paracetamol and opioids only. The most common prescribed opioid was oxycodone (87.3% of patients). Only 19% of patients were prescribed nonsteroidal anti-inflammatories (NSAIDs). The median (IQR) average daily OMEDD was 50.2 mg (30.3–77.9).

Conclusion

We identified high use of opioids analgesics as the main strategies for pain control after hip and knee replacement in hospital. Other analgesics were much less frequently used, such as NSAIDs, and always in combination with opioids and paracetamol.
Under Armour – Use of personal protective equipment for simulated CPR of COVID-19 patients: an observational study
Authors: Kraus S. , Macherey R. , Rimkus L. , Tschudin-Sutter S. , Marsch S. , Sellmann Timur
Published: May 2024

Background

Personal protective equipment (PPE) protects healthcare workers and patients. Data on guideline compliance on how to dress (donning) or remove (doffing) PPE and the assistance among multiple participants (buddying) are limited. This study assesses the quality of donning, doffing, and buddying of PPE in a simulated medical emergency.

Method

Physicians handling a simulated cardiac arrest of a COVID-19 patient. Adjacent to the victim, PPE was available. The appropriateness of PPE choice was assessed by using video recordings, with each individual participant being analyzed from the beginning of the simulation scenario from two perspectives regarding the selection of items during donning and doffing, hygiene aspects, time, and team support (buddying). The primary outcome was the number of participants being appropriately protected, defined as both wearing (a) all PPE items provided, and (b) all PPE items correctly at the time of first patient contact (FPC). Secondary outcomes included the timing of participants being appropriately protected. Statistical analysis was performed using SPSS (version 28). Mann–Whitney test, chi-square test, and linear regression analysis were performed as appropriate.

Results

At first patient contact 21% (91/437) were correctly protected. One or more incorrect PPE items were found in 4% (19/437), whereas 61% (265/437) wore one or more PPE items incorrectly. In 14% (62/437), one or more PPE items were missing. The time interval between donning start and FPC was 66 (55–78) sec. Time to FPC was longer in correctly than in incorrectly protected participants 77 (66–87) vs. 64 (54–75) sec; p < 0.001) and decreased by 7 ± 2 s per PPE item omitted (P = 0.002). Correct doffing was observed in 192/345 (56%), while buddying occurred in 120 participants (27%), indicating that they either assisted other participants in some manner (verbally or physically) or received assistance themselves.

Conclusions

Our findings imply a need for education in correct and timely PPE donning and doffing. Donning PPE as intended delayed FPC. This and the influence of buddying needs further investigation (German study register number DRKS00023184).
A multi-country examination of the relationship between perfectionism and disordered eating: the indirect effect of obsessive beliefs and obsessive-compulsive symptoms
Authors: Fekih-Romdhane Feten , Pardini Susanna , Hallit Souheil , Novara Caterina , Brytek-Matera Anna
Published: May 2024

Background

Despite the extensive literature on the association between perfectionism and disordered eating (DE), only scant attention has been given to the underlying processes that may mediate this relationship. The present study aimed to contribute to existing literature by investigating the direct and indirect relations between perfectionism and DE through obsessive-compulsive disorder (OCD) symptoms and obsessive beliefs, among community adults from three different countries and cultural backgrounds (i.e. Poland, Italy and Lebanon).

Methods

This is a cross-sectional study that was carried-out among 977 community adults (77.1% females, mean age: 21.94 ± 3.14 years) using the snowball sampling technique.

Results

Obsessive-compulsive disorders (OCD) symptoms and obsessive beliefs had a partial indirect effect in the relationship between multidimensional perfectionism and disordered eating. Higher multidimensional perfectionism/obsessive beliefs were significantly associated with greater OCD symptoms and directly associated with higher DE scores. Finally, higher OCD symptoms were significantly linked to higher DE scores.

Conclusion

The preliminary results suggest that it would be helpful for clinicians to routinely include measures of perfectionism, OCD and obsessive beliefs when dealing with individuals who present DE problems. In addition, results hold promise for the combined use of perfectionism and OCD interventions as a potentially beneficial treatment option for DE concerns.
The effect of impulsive personality traits on prospective memory under different task importance conditions
Authors: Guo Yunfei , Gan Jiaqun , Li Yongxin
Published: May 2024

Background

Prospective memory (PM) refers to the ability to perform planned activities in the appropriate future situations. It needs to be planned in advance and processed through multiple stages such as encoding, retention, retrieval, and execution, which usually require more attention resources. Impulsivity trait individuals are usually characterized by lack of consideration, premature expression, excessive risk-taking and easy to make inappropriate reaction, so they are more likely to show disadvantages in PM. Nevertheless, increasing the importance of PM tasks can promote more adequate and effective cue encoding, and encourage individuals to devote attention to PM tasks, which may change the disadvantage of impulsivity individuals in PM performance.

Methods

In this study, the between-subjects design of 2 (trait type: high-impulsivity trait, low-impulsivity trait) ×2 (task importance: important, unimportant) was adopted in the experiment, the 2-back task was used for the ongoing task, and the focal cues were used for the PM task cues.

Results

The results showed that the PM accuracy of high-impulsivity trait individuals was lower than that of low-impulsivity trait individuals under the task unimportant condition, but there was no difference between the two traits groups under the task important condition.

Conclusions

The results of this study suggested that high-impulsivity trait individuals had a deficit in PM performance, but emphasizing the importance of PM tasks can compensate for their disadvantage in PM performance.
Prevalence of multiple micronutrient powders consumption and its determinants among 6- to 23-month-old children in East Africa: a mixed effect analysis using the recent population based cross sectional national health survey
Authors: Terefe Bewuketu , Chekole Bogale
Published: May 2024

Background

To address iron deficiency anemia, Multiple Micronutrient Powders (MMNPs) can be sprinkled onto any semisolid diet and given to young children. There is currently no data on actual MMNPs uptake by children; hence, the study’s goal was to investigate MMNPs and determinants among children aged 6–23 months in East Africa.

Methods

Data from the 2016–2022 East Africa demographic and health survey extracted from Kids Records (KR) files were used in this study. A total of 33,324 weighted 6- to 23-month-old child samples were included. For assessing model fitness and contrast, the intra-class correlation coefficient, median odds ratio, proportional change in variance, and deviance were used. A multilevel logistic regression model was applied to identify variables that may influence MMNPs intake. In the multivariable multilevel logistic regression analyses, variables were judged to be significantly linked with MMNPs intake if their p-values were < 0.05.

Results

In East Africa, the prevalence of MMNPs intake among infants aged 6–23 months was 6.45% (95% CI, 6.19%, 6.22%). Several factors were found to be significantly associated with MMNPs consumption. These factors include older maternal age (AOR = 1.23, 95% CI, 1.09, 1.39) and (AOR = 1.46, 95% CI, 1.23, 1.73), poorer (AOR = 0.73, 95% CI, 0.64, 0.84), middle (AOR = 0.75, 95% CI, 0.66, 0.86), richer (AOR = 0.61, 95% CI, 0.52, 0.71), and richest (AOR = 0.49, 95% CI, 0.41, 0.59) as compared to poorest, having employment status (AOR = 0.65, 95% CI, 0.59, 0.71), mass media exposure (AOR = 1.61, 95% CI, 1.35, 1.78), longer birth interval (AOR = 1.19, 95% CI, 1.28, 1.36), place of delivery (AOR = 1.46, 95% CI, 1.28,1.66), and mothers from rural areas (AOR = 0.71, 95% CI, 0.62,0.80).

Conclusions

Overall, MMNPs intake was lower than the national and international recommendations. Only seven out of every hundred children received MMNPs. Improving maternal preventive health care and supporting marginalized women will have a positive impact.
Translating Utopia
Authors: Turner Lindsay
Published: May 2024

This essay considers multiple forms of transatlantic translation in the work of the contemporary French poet-translator Stéphane Bouquet (b. 1968). Because Bouquet is an established translator of poets of the US New York School (Paul Blackburn, James Schuyler), Bouquet’s appearance in English marks a new stage of the New York School’s life and history—a crossing from English to French and back by which earlier forms of social, erotic, and political awareness are refracted through a different sensibility and an expanded global consciousness. Tracing the complexities of these crossings helps reframe translation not as a single one-way trajectory from source to target language but rather as a multiple and dynamic back-and-forth and a temporal opening to new possibilities akin to the version of queerness suggested by José Esteban Muñoz as “the work of not settling for the present, of asking and looking beyond the here and now.”
Afterword
Authors: Bhattacharyya Debjani
Published: May 2024

If one were to chart the momentous transformations that South Asia witnessed in the twentieth century, the sea and its coasts would be an essential cipher. The geopolitical, socio-legal, and economic transformations over the past century in South Asia are a seaborne phenomenon, among others. This backdrop often remains suppressed when sketching its contemporary history. As this afterword details, the special section “Port Environments in South Asia” shows that as ports and littoral societies receded from scholarly focus, the relationship among state, market, and the ocean intensified at these edge spaces. Without careful attention to the recomposition of this relationship over the twentieth century, it is difficult to make sense of the current geopolitical consolidation between India and China in the Indian Ocean. From coasts, brackish backwaters, and dynamic littorals, the essays in this themed section open new ways of understanding the reconstitution of power in Asian port environments in a climate-changed world.
What Makes a Natural Harbor?
Authors: Anusha Chandana
Published: May 2024

The Mundra Port on the Gulf of Kutch in western India is one of India's largest port projects today. This article takes the port-circulated narrative of the coast being a natural harbor as its starting point, to show how fresh water was central to official maritime projects until the early postcolonial period. Conserving mangroves and freshwater creeks was not antithetical to maritime ports but part of the same administrative project. Political and infrastructural shifts from the river to the tide naturalized the erasure of coastal fresh water and transformed the coast into a singularly tidal space, creating the conditions for the development of a large-scale, high-technology shipping port.
Struggles on the Supply Chain
Authors: Billeaux-Martinez Michael
Published: May 2024

In this entry the author discusses the concepts of structural and associational power and their relationship to the logistics sector. He argues that the emphasis on structural power that has generated so much interest in organizing the logistics sector on the left today ought to be tempered by a clarification of structural power as essentially a potential rather than already-actual power, and the notion of associational power promoted to a place of higher priority.
Two instability results in general relativity
Authors: Μοσχίδης Γεώργιος
Published: May 2024

Ένα θεμελιώδες ερώτημα που προκύπτει κατά τη μελέτη των εξισώσεων πεδίου του Einstein στη γενική σχετικότητα είναι αυτό της ευστάθειας των λύσεων κάτω από διαταραχές των αρχικών τους συνθηκών. Σε αυτή τη διατριβή, θα αποδείξουμε δύο αποτελέσματα σχετιζόμενα με φαινόμενα αστάθειας των εξισώσεων Einstein σε χωροχρόνους που ανήκουν σε δυο διακριτές γεωμετρικές κατηγορίες. Το πρώτο μέρος της διατριβής αφορά την κατηγορία των χρονικά αναλλοίωτων και ασυμπτωτικά επίπεδων χωροχρόνων· τέτοιοι χωροχρόνοι μοντελοποιούν την τελική κατάσταση της εξέλιξης απομονωμένων βαρυτικών συστημάτων. Το πρώτο αποτέλεσμα αυτής της διατριβής αποτελεί ένα θεώρημα αστάθειας για τις λύσεις της γραμμικής κυματοεξίσωσης (την οποία μπορεί να δει κανείς ως ένα απλοποιημένο γραμμικό μοντέλο των μη γραμμικών εξισώσεων Einstein) σε χωροχρόνους που διαθέτουν (μη κενή) εργοπεριοχή αλλά δεν έχουν ορίζοντα γεγονότων. Το αποτέλεσμα αυτό είχε διατυπωθεί ως εικασία από τον Friedman το 1978. Ως πόρισμα του θεωρήματος αυτού, αποδεικνύουμε ένα αποτέλεσμα αστάθειας για την εξέλιξη στον χρόνο ακουστικών διαταραχών του υδροδυναμικού στροβίλου, ένα φαινόμενο που μελετήθηκε για πρώτη φορά αριθμητικά από τους Oliveira-Cardoso-Crispino. Το δεύτερο μέρος της διατριβής αφορά την κατηγορία των ασυμπτωτικά anti-de Sitter χωροχρόνων. Οι χωροχρόνοι αυτοί προκύπτουν ως λύσεις των εξισώσεων Einstein με αρνητική κοσμολογική σταθερά και απαντώνται συχνά στη βιβλιογραφία της φυσικής υψηλών ενεργειών. Το 2006, οι Dafermos-Holzegel διατύπωσαν την εικασία ότι ο χωροχρόνος anti-de Sitter είναι ασταθής ως λύση των εξισώσεων Einstein στο κενό όταν επιβάλλονται ανακλαστικές συνοριακές συνθήκες στο άπειρο. Το δεύτερο αποτέλεσμα αυτής της διατριβής είναι η απόδειξη της αστάθειας του χωροχρόνου AdS για το σύστημα Einstein-null dust.
Systems Biology in ELIXIR: modelling in the spotlight
Authors: Martins dos Santos Vitor , Anton Mihail , Szomolay Barbara , Ostaszewski Marek , Arts Ilja , Benfeitas Rui , Dominguez Del Angel Victoria , Domínguez-Romero Elena , Ferk Polonca , Fey Dirk , Goble Carole , Golebiewski Martin , Gruden Kristina , Heil Katharina F. , Hermjakob Henning , Kahlem Pascal , Klapa Maria I. , Koehorst Jasper , Kolodkin Alexey , Kutmon Martina , Leskošek Brane , Moretti Sébastien , Müller Wolfgang , Pagni Marco , Rezen Tadeja , Rocha Miguel , Rozman Damjana , Šafránek David , T. Scott William , Sheriff Rahuman S. Malik , Suarez Diez Maria , Van Steen Kristel , Westerhoff Hans V , Wittig Ulrike , Wolstencroft Katherine , Zupanic Anze , Evelo Chris T. , Hancock John M.
Published: May 2024

In this white paper, we describe the founding of a new ELIXIR Community - the Systems Biology Community - and its proposed future contributions to both ELIXIR and the broader community of systems biologists in Europe and worldwide. The Community believes that the infrastructure aspects of systems biology - databases, (modelling) tools and standards development, as well as training and access to cloud infrastructure - are not only appropriate components of the ELIXIR infrastructure, but will prove key components of ELIXIR’s future support of advanced biological applications and personalised medicine. By way of a series of meetings, the Community identified seven key areas for its future activities, reflecting both future needs and previous and current activities within ELIXIR Platforms and Communities. These are: overcoming barriers to the wider uptake of systems biology; linking new and existing data to systems biology models; interoperability of systems biology resources; further development and embedding of systems medicine; provisioning of modelling as a service; building and coordinating capacity building and training resources; and supporting industrial embedding of systems biology. A set of objectives for the Community has been identified under four main headline areas: Standardisation and Interoperability, Technology, Capacity Building and Training, and Industrial Embedding. These are grouped into short-term (3-year), mid-term (6-year) and long-term (10-year) objectives.
Protocol for correlation of histological risk assessment/scoring system with a depth of invasion in oral squamous cell carcinoma
Authors: Sonone Archana , Hande Alka , Pakhale Aayushi , Gawande Madhuri , Patil Swati
Published: May 2024

Introduction The commonest type of cancer in the head and neck region is oral squamous cell carcinoma (OSCC) due to its high rates of occurrence and mortality. The early diagnosis of oral cancer gives better prognosis. Brandwein-Gensler criteria predict the early stage of OSCC cases with a high risk of locoregional recurrence. Objectives To correlate Brandwein-Gensler criteria and depth of invasion of OSCC with three-year survival. Methodology In the study, This study will include 80 random histopathologically-diagnosed cases of OSCC. hematoxylin-eosin (HE)-stained section slides will be used to evaluate, Brandwein and Gensler criteria by three histopathologists in a blinded manner. The depth of invasion assessment will be done from the basement-membrane (BM), in regions where the BM has been lost, as well as from an illustrative line connecting the BM from the neighbouring epithelium to the point of deepest tumour invasion in the connective-tissue stroma with the help of a research microscope (Leica-DMLB2) in resected tissue specimens of OSCC cases. Expected results The present study will find the correlation between Brandwein-Gensler criteria and depth of invasion in OSCC in order to evaluate the locoregional recurrence in OSCC cases. In high-risk OSCC cases, there may be an increased depth of invasion in resected tissues. Conclusions We hypothesized that the correlation between Brandwein-Gensler criteria and depth of invasion can be used as an independent predictor for locoregional recurrence in OSCC.
Pulmonary function in Thai patients with systemic sclerosis; a single center 6-year retrospective study
Authors: Pirompanich Pattarin , Sathitakorn Ornnicha , Sakulvorakitti Thitisak
Published: May 2024

Background Pulmonary involvement is a major cause of internal organ complication and the leading cause of death in patients with systemic sclerosis (SSc). This study aimed to demonstrate the characteristics of pulmonary function (PF) in Thai patients with SSc and the association between PF and body mass index (BMI) and anti-topoisomerase (anti-Scl70). Methods All patients diagnosed with SSc in our tertiary care teaching hospital database between 2016 and 2021 were reviewed and analyzed. Results Of 211 SSc patients, 128 patients who underwent the PF test were enrolled; 102 (79.7%) were female. The mean age was 54 years. The median BMI for all patients was 21.7 kg/m2. Regarding anti-Scl70, 10.9% of patients were positive, 7.8% were negative, and the status was unreported for 81.3%. The mean (SD) forced expiratory volume in one second (FEV1) forced vital capacity (FVC) ratio was 0.8 (0.1). The mean (SD) % predicted values of FEV1, FVC, and diffusing capacity of the lungs for carbon monoxide (DLCO) were 76.3 (16.3), 69.1 (15.8), and 75.5 (22.8), respectively. A restrictive spirometry pattern (RSP) was found in 78.8% of the patients. DLCO had a moderate positive linear correlation with FVC (r=0.50, p <0.001) and a moderate negative linear correlation with BMI (r=-0.36, p <0.001). However, there was no correlation between FVC and BMI. There was no statistical difference in demographic data or the presence of anti-Scl70 among patients with or without RSP. Conclusions RSP is common among Thai patients with SSc. However, the power of using demographic data and the presence of anti-Scl70 to determine the probability of pulmonary involvement remains limited.
Differential Expression of Immunohistochemical Markers in Ameloblastoma & Ameloblastic Carcinoma: A Systematic Review and Meta-analysis of observational studies
Authors: Mishra Saleena , Panda Swagatika , Mohanty Neeta , Mishra Swati , Gopinath Divya , Panda Saurav , Anil Sukumaran
Published: May 2024

Background Differentiating between ameloblastoma (AB) and ameloblastic carcinoma (AC) is difficult, especially when AB has atypical cytological characteristics or an uncommon clinical history. This systematic review and meta-analysis aimed to elucidate the differential expression of immunohistochemical markers between AB and AC. Methods We conducted a thorough search of PUBMED and SCOPUS according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines to identify cross-sectional studies that compared the expression of immunohistochemical markers in AB and AC. We used a random-effects model to analyze the risk ratios and their corresponding 95% confidence intervals (CIs). The quality of the included studies was assessed using the Newcastle-Ottawa scale. The Egger’s test was used to assess publication bias. Results In total, 301 articles were identified. After excluding irrelevant titles and abstracts, 86 articles were selected for full-text review. We categorized the 41 markers into proliferative and non-proliferative markers. Among non-proliferative markers, nuclear markers were differentially expressed in AB and AC. SOX2 was the only marker that significantly differentiated AB and AC, with an RR of -0.19 (CI 0.10-0.36, I2=0). Conclusion The current evidence suggests the significance of SOX2 in differentiating between AB and AC, warranting prospective confirmation in well-defined extensive studies. We highlight the paucity of high-quality replicated studies of other markers in this field. Collaborative efforts with standardized techniques are necessary to generate clinically useful immunohistochemical markers.
Perfil Competencial del Profesorado Andaluz en Seguridad Digital: Evaluación de la Protección de Datos y Privacidad de acuerdo con el Marco Común de Competencia Digital Ciudadana (DigComp) (Competency Profile of Andalusian Teachers in Digital Security: Evaluation of Data Protection and Privacy in accordance with the Common Framework of Digital Citizen Competence (DigComp))
Authors: Villén-Contreras Rafael , Agreda-Montoro Miriam , Rodríguez-Moreno Javier
Published: May 2024

La incorporación de dispositivos electrónicos conectados a la red presenta desafíos y riesgos en términos de seguridad digital. Este artículo presenta los hallazgos de una investigación enfocada en la evaluación de la competencia digital de los educadores en lo que respecta a la salvaguarda de datos personales, conforme al marco europeo DigComp 2.2. En el estudio tomaron parte 497 docentes del sistema educativo andaluz a través de un cuestionario validado por expertos sobre Competencia en Seguridad Digital. Este instrumento, de enfoque integral y dividido en cuatro dimensiones, se centra en la Dimensión "Protección de Datos Personales", abarcando 15 ítems. Este enfoque nos posibilita comprender el nivel competencial de los docentes durante su desempeño. Se observan disparidades significativas en la salvaguarda de datos personales asociadas a la edad, la antigüedad docente y las horas de formación, indicando que aquellos de mayor edad, antigüedad y mayor formación obtienen calificaciones más elevadas. En resumen, los docentes andaluces que participan en este estudio exhiben una disposición favorable a la seguridad para proteger sus datos personales, aunque presentan carencias asociadas al trato seguro y responsable de estos durante la navegación por la red.
Millennials vs Centennials: ¿diferentes formas de aprender? (Millennials vs Centennials: Different Ways of Learning?)
Authors: Sánchez-Caballé Anna , Cela-Ranilla José , Esteve-Mon Francesc
Published: May 2024

Este trabajo constituye un análisis comparativo enfocado en los patrones de aprendizaje adoptados por dos generaciones distintas de estudiantes: Millennials y Centennials. La noción de "patrones de aprendizaje" se centra en la organización que las personas emplean para acceder al conocimiento y abordar tanto tareas académicas como cotidianas. En la investigación han participado 315 estudiantes universitarios del ámbito educativo, quienes fueron sometidos a un análisis mediante la prueba U de Mann Whitney. Los resultados obtenidos revelan diferencias significativas entre ambas generaciones. En particular, los Millennials exhiben una mayor inclinación hacia la búsqueda y posesión de información detallada, contrastando con los Centennials, quienes presentan valores estadísticamente más elevados al emplear patrones asociados al trabajo autónomo. Esta disparidad sugiere que, en los últimos quince años, el estudiantado ha forjado enfoques de aprendizaje distintos, probablemente influenciados por diversos factores, tales como avances tecnológicos, cambios en el modelo educativo y situaciones derivadas de la pandemia. Este fenómeno plantea la necesidad imperante de reflexionar sobre la realidad social experimentada en estos últimos años y sobre cómo la acción docente debe adaptarse a estos cambios. Este estudio contribuye al entendimiento de estos cambios y brinda una base sólida para la toma de decisiones pedagógicas.
Forgetful Consumers and Consumption Tracking
Authors: Bao Ying , Landry Peter , Shi Mengze
Published: May 2024

We study the market consequences of advances in consumption tracking technologies—such as mobile banking apps that help consumers monitor their spending and avoid overdrawn accounts—using a two-period consumption model. In the model, consumers pay a penalty fee if they consume in both periods. In the second period, consumers may be forgetful of their first-period consumption, although the use of consumption tracking can remind them. According to our analysis, the availability of consumption tracking often helps consumers at the expense of the firm; such benefits may be direct, where consumers make use of the technology to avoid penalty fees, or indirect, where the mere availability of consumption tracking forces the firm to lower its penalty fee. If consumers are partially sophisticated regarding their forgetfulness, however, the availability of consumption tracking may instill a false sense of security in that consumers expect to use consumption tracking to avoid penalty fees but ultimately, decide not to bother, making them especially susceptible to penalty fees. In some cases, the availability of consumption tracking may actually compel a firm to impose a penalty fee that would not otherwise be viable, leading to higher profits and lower consumer surplus. As we show, this scenario is attained within an intermediate range of forgetfulness and at a level of (partial) sophistication for which consumers overestimate their demand for the technology.

This paper was accepted by Dmitri Kuksov, marketing.

Funding: M. Shi appreciates financial support from HKUST Yuk-Shee Chan Professorship Fund and China NSF [Grant 72272036].

Supplemental Material: The online appendix is available at https://doi.org/10.1287/mnsc.2023.00522 .
Group structure and diurnal behavior in a large colony of Mimon cozumelae in Yucatán, México.
Authors: Romo-Hernández Kinari , Ortega Jorge , Bolívar-Cimé Beatriz , MacSwiney G. M. Cristina
Published: May 2024

The Phyllostominae is a Neotropical subfamily of bats that include species considered sensitive to habitat disturbance, but that are the poorly known.  The Cozumelan Golden Bat, Mimon cozumelae, is a rare phyllostomine that inhabits forests and semi-deciduous tropical forests from central México to western Colombia.  This study describes for the first time, the social organization and diurnal behavior of M. cozumelae to provide basic information about the social relationships of this elusive species.  We captured and marked individuals inhabiting a cave in Yucatán, México in 2020 and 2021.  Observations were carried out filming its behavior inside the cave in two seasons, breeding (March-July) and non-breeding (August-January).  We constructed an ethogram and classified the observed behaviors into states and events in each season.  A total of 103 individuals (47 females and 56 males) of M. cozumelae were captured.  The sex ratio was not different from 1:1.  The size of the groups did not vary throughout the seasons.  The most frequent behaviors performed by M. cozumelae were resting, followed by flight, self-grooming, wing extension, and social grooming.  The group composition most common in both seasons was multi-male, ruling out the typical formation of harems in the breeding season for this species.  Copulation and maternal grooming were recorded for the first time in the reproductive season.  This bat exhibits social grooming, which in theoretical terms could categorize it as a species that forms societies.  This study contributes updated information regarding group size and composition, and especially diurnal behavior of M. cozumelae.  It is suggested that this work serves as a baseline to investigate its social systems (behavioral ecology) in depth, and when carrying out conservation plans for this species.
Rediscovery of Oryzomys fulgens: implications for the taxonomy of Oryzomys
Authors: González-Ruiz Noe , Ramírez-Pulido José , Jiménez-Gutiérrez Alan Roy , Arroyo-Cabrales Joaquín
Published: May 2024

The rodents belonging to the genus Oryzomys are among the most widely distributed groups inhabiting North America.  Currently, 13 species with continental, peninsular, or insular distributions are known.  However, this genus also faces significant conservation challenges, primarily due to climate change and other human-related activities.  One such enigmatic species is Oryzomys fulgens.  Its main challenge lies in the fact that it was originally described from an imprecise type locality, simply labeled as "Mexico." Fortunately, recent research has delimited its range to the Basin of México. Nonetheless, the lack of comparison between its holotype and other specimens of the genus in México has hindered the accurate assignment of its name to any known taxon, despite being one of the oldest names within the genus, O. fulgens has rarely been used since its original description.  During our research, we collected two specimens of O. fulgens from Xochimilco, México City, a remnant wetland situated within the Basin of México, nestled within one of the largest and most urbanized cities globally.   To properly assess its taxonomic status, we compared our specimens with the holotype of O. fulgens, as well as with other species from southern and western México.  The considerable morphological differences we observed in O. fulgens, coupled with its distinct and unique habitat as the sole species of the genus occupying temperate regions at high elevations, lead us to propose that it is indeed a distinct species, separate from O. mexicanus and O. albiventer.  Historically, its distribution was likely limited to the Basin of México. Today, O. fulgens faces serious conservation problems, mainly due to the restriction of its current distribution, as far as we know, confined to Xochimilco.  Although the ancestral agricultural system known as "chinampas" might provide an ideal environment for sustaining populations of this species, it remains under significant pressure from various human activities, predators, and competition with invasive species like the black rat.  Urgent conservation efforts are needed to safeguard the unique habitat of O. fulgens and protect this enigmatic species from further decline.
CRISPR-Cas9 Genome Editing Technology for Zoonotic Disease Control in Indonesia: A Comprehensive Review
Authors: Adnyana I Made Dwi Mertha , Eljatin Dwinka Syafira , Sudaryati Ni Luh Gede , Adiwinoto Ronald Pratama , Raza Syed Meesam , Da Cruz Zito Viegas
Published: May 2024

The increasing emergence of zoonotic diseases originating from vectors, rodents, mammals, and others has increased the potential for outbreaks of pandemics in the Indonesian territory. Although control and prevention have been implemented, these efforts have not yet revealed a bright spot; therefore, elaboration with advanced CRISPR-Cas9 technology is a way to accelerate efforts to control zoonotic diseases in Indonesia. However, there is limited literature on this topic. This review aims to comprehensively describe, identify, and summarize the application of CRISPR-Cas9 genome-editing technology in zoonotic disease control in Indonesia. Our findings show that CRISPR-Cas9 genome editing technology offers an innovative approach for zoonotic disease control by targeting disease vectors, modifying animal reservoirs, improving disease surveillance, enhancing vaccine development, and exploring traditional medicine candidates and immunotherapy. The high level of precision, efficiency, and versatility in targeting genomes capable of disrupting, damaging, and disrupting the disease transmission cycle in pathogens makes CRISPR-Cas9 highly effective. However, challenges such as off-target impacts, regulatory complexity, and ethical considerations must be overcome with inter- and multidisciplinary collaboration to promote transparency, equity, and public engagement throughout the process of implementing this technology in the field, especially in Indonesia.
Token graphs of Cayley graphs as lifts
Authors: Dalfó Cristina , Fiol Miquel Àngel , Pavlíková Sona , Sirán Jozef
Published: May 2024

This paper describes a general method for representing $k$-token graphs of Cayley graphs as lifts of voltage graphs. This allows us to construct line graphs of circulant graphs and Johnson graphs as lift graphs on cyclic groups. As an application of the method, we derive the spectra of the considered token graphs. The method can also be applied to dealing with other matrices, such as the Laplacian or the signless Laplacian, and to construct token digraphs of Cayley digraphs.
Effects of Personal Social Capital on the Isomorphism of Stricto Sensu Graduate Courses
Authors: Meier de Carvalho Albano Leandro , Popadiuk Silvio
Published: May 2024

This research investigates whether personal social capital influences institutional isomorphism. Two premises were considered: i) neo-institutional theory and institutional isomorphism provide tools for explaining the homogenization of practices and structures between organizations and ii) personal social capital in organizations contributes to institutional isomorphism. The study was developed in two aspects — one theoretical and the other empirical — which made it possible to corroborate the proposed hypothesis. Quantitative research methods were used in the empirical aspect, with a sample of 176 coordinators of stricto sensu postgraduate courses. Higher education institutions (HEIs) were evaluated in two facets: i) organizations subject to isomorphic phenomena, such as firms from other sectors, and ii) responsibility for the perpetuation of these processes, from the training of teachers (who will become masters of future managers) and the knowledge they generate. At the end of the research, it was confirmed that personal social capital has a positive effect on institutional isomorphism through the internal relations of the coordinators. The manifestations of coercive, normative, and mimetic isomorphisms in the HEIs were also identified.
An interview with BAOMS president Miss Daljit Dhariwal
Authors: Nortley M
Published: May 2024

Juggling parenthood, mentoring and a pioneering surgical career is not easy – Miss Daljit Dhariwal reflects on the challenges, joys and how it can be done.
Il saurano
Authors: Sidraschi Diego
Published: May 2024

The present contribution aims at depicting a sketch of Saurian, a Germanic variety spoken in Sauris/Zahre, in the Carnic Alps in Friuli Venezia Giulia. Firstly, the article will discuss the history of the settlement and the origin of the colonizers based on linguistic evidence. Secondly, the main focus will be the community’s multilingual repertoire and the laws and regulations which protect minority codes. Successively, the analysis will aim at outlining the linguistic characteristics of Saurian. In doing so, the attention will be on the synchronic description of the variety as it is attested today, with the addition of some diachronic considerations. The linguistic contact between Saurian and the liminal Romance varieties is a pivotal topic so long as it allows us to observe the multiple examples of interference in the linguistic system of the Saurian language, on all levels of linguistic analysis. Finally, the article will focus on the numerous initiatives for the maintenance and the revitalization of the Saurian language.
Il timavese
Authors: Zuin Francesco
Published: May 2024

The work aims to provide a description of the sociolinguistic and linguistic reality of the hamlet of Timau in the municipality of Paluzza. In contrast to the other villages of the Municipality, the population of Timau has been speaking for centuries, alongside Italian and Friulian, the Timavese code, a Carinthian based variety that nevertheless displays distinctive linguistic characteristics at all levels. In the paper we will present the origins of the village, the sociolinguistic position of Timavese in the community’s repertoire, the similarities and differences between Timavese and Carinthian and the corpus and status planning created for this variety after its recognition by the national law 482/1999 (“Norme in materia di tutela delle minoranze linguistiche storiche”), aimed at protecting the historical linguistic minorities recognized in the national territory.
Il sappadino
Authors: Caria Marco
Published: May 2024

This article focuses on the linguistic and sociolinguistic situation of Sappada – Plodn, a village in the Carnic Alps, which – just as the close Sauris and Timau – differs from the rest of its neighbouring villages as it is an ancient settlement of Austrian-Bavarian origin. In this essay, the author will provide an outline of Sappada’s historical origins and focus on a description of its peculiar Germanic dialect, which is still preserved and spoken by the local population. Then the initiatives to protect Sappada’s linguistic heritage will be illustrated from a sociolinguistic point of view, also in the light of the most important traditions that make the village a very important tourist attraction.
I testamenti dei cittadini romani d’Egitto tra storia sociale e prassi giuridica. Dal I secolo d.C. a Severo Alessandro
Authors: Colella Lucia Consuelo
Published: May 2024

Lucia Consuelo Colella offers both a critical edition and a historical and juridical analysis of the documentation for Roman testamentary practice in Egypt prior to the constitution of Alexander Severus, which authorized the use of the Greek language in drafting Roman wills. Before this measure, the Roman citizens in Egypt, most of whom spoke Greek, used drafts and translations in Greek, as can be seen from the surviving documents. The material analyzed here includes Roman wills which have survived on wax tablets or papyrus both in Latin and Greek. There are 26 wills, one of which is identified for the first time and two unpublished documents on testamentary dispositions. The critical edition of these documents also takes into account paratextual and linguistic aspects, for the first time in some cases. The new information that emerges forms the basis for an analysis of the socio-economic profile and the language skills of the testators, beneficiaries and witnesses in relation to the groups of Roman citizens in Egypt for whom we have information from other sources, as well as reflections on the representativity of the papyrological sources with regard to the proportion of soldiers and veterans among Roman citizens in the province prior to the Constitutio Antoniniana. In the light of new textual information, it is also possible to address the relationship between Roman law and local practice in the period before the constitution of Alexander Severus, also in terms of the extension of the privilege of the so-called testamentum militis.
El evangelio antropocénico según Anacristina Rossi
Authors: Botía Alejandro
Published: May 2024

RESUMEN: A partir de los cuentos "Abel" (2013), "La Incompleta" (2015) y "La esperada" (2019), de la escritora costarricense Anacristina Rossi, este artículo explora la manera en que esta trilogía narrativa reconfigura, desde la ciencia ficción, las nociones de identidad, naturaleza y sentido de lo humano. Con base en las teorías de la ecocrítica, la ecocrítica poscolonial y el ecofeminismo se analizan las estrategias discursivas con que Rossi interconecta las preocupaciones antropocénicas sobre la sostenibilidad de la civilización con la idea del fin del mundo y un nuevo génesis, a fin de desentrañar su crítica contra todos los sistemas de dominación: patriarcales, económicos, coloniales, raciales y de género, que imperan en la actualidad. Abstract: Based on the stories “Abel” (2013), “La incompleta” (2015) and “La esperada” (2019), by the Costa Rican writer Anacristina Rossi, this article explores the ways in which this narrative trilogy draws from science fiction to reconfigure the notions of identity, nature, and what it means to be human. Drawing on the theories of ecocriticism, postcolonial ecocriticism, and ecofeminism, Rossi's discursive strategies to interconnect anthropocenic concerns about the sustainability of civilization with the idea of the end of the world and a new genesis are analyzed to unravel her critique against all systems of domination that prevail today: patriarchal, economic, colonial, racial, and gendered.