bluuebunny/crossref_metadata_2025 huggingface dataset:
FILSAFAT STOISISME DAPAT MELAHIRKAN PERASAAN SKEPTIS PADA HAL BAIK YANG AKAN TERJADI
Authors: MASTORY BAGUS , SYUKUR MUHAMMAD
Published: January 2025

Stoicism, a philosophy developed by Zeno and later advanced by thinkers such as Epictetus, Seneca, and Marcus Aurelius, emphasizes the importance of self-control, virtue, and the acceptance of life's inherent realities. Central to Stoic philosophy is the belief that true happiness arises from our ability to regulate our reactions and attitudes toward external events, which are often beyond our control. Consequently, Stoicism fosters a sense of skepticism regarding the expectation of positive outcomes, given that all aspects of life are inherently uncertain and transient. This skepticism, however, should not be conflated with pessimism; rather, it serves as a mental preparation to embrace all possible outcomes without attachment to a specific result. By emphasizing the acceptance of uncertainty and prioritizing virtue as the ultimate aim, Stoicism teaches detachment from expectations of favorable circumstances and encourages a focus on managing emotions and responses. In this framework, skepticism functions as a tool to mitigate disappointment, preserve inner tranquility, and diminish reliance on external conditions that may disrupt life's equilibrium.
ABSTRAKFilsafat Stoisisme, yang dikembangkan oleh Zeno dan dipopulerkan oleh filsuf-filsuf seperti Epictetus, Seneca, dan Marcus Aurelius, menekankan pentingnya pengendalian diri, kebajikan, dan penerimaan terhadap kenyataan hidup. Salah satu prinsip utama Stoisisme adalah keyakinan bahwa kebahagiaan sejati bergantung pada kemampuan kita untuk mengelola reaksi dan sikap terhadap peristiwa eksternal, yang sering kali berada di luar kendali kita. Sebagai konsekuensinya, Stoisisme dapat melahirkan perasaan skeptis terhadap harapan akan hal baik yang akan terjadi, karena segala sesuatu dalam hidup dianggap tidak pasti dan sementara. Skeptisisme ini bukan berarti pesimisme, tetapi lebih kepada persiapan mental untuk menerima segala kemungkinan tanpa bergantung pada hasil yang diinginkan. Dengan menekankan penerimaan terhadap ketidakpastian dan fokus pada kebajikan sebagai tujuan utama, Stoisisme mengajarkan bahwa kita sebaiknya tidak terlalu terikat pada ekspektasi terhadap hal-hal baik, melainkan lebih pada bagaimana kita mengelola perasaan dan respons kita terhadapnya. Dalam konteks ini, skeptisisme menjadi alat untuk mengurangi kekecewaan dan menjaga kedamaian batin, menjauhkan kita dari ketergantungan pada hasil eksternal yang dapat mengganggu keseimbangan hidup.
REPRESENTASI PERSONAL INTEGRITY FRONT OFFICE DALAM TUGAS HUMAS UNIVERSITAS NUSA NIPA
Authors: MEAK APOLLONIA WINELCI DUA , BASTIAN MAYELUS DORI , SEDU VIKTOR ARIESTYAN
Published: January 2025

The task of public relations has an important role in every institution because the task of public relations or public relations is one of the strategies in shaping the image of the institution, whether it is a positive image or a negative image. In forming the image of an institution, public relations usually has extensive relationships, which requires personal integrity. This research aims to find out how front office personal integrity is represented in Nusa Nipa University's public relations duties and find out the obstacles to Nusa Nipa University's front office services. This research uses a qualitative descriptive approach. Data was collected by interviews and observations. The results of this research show that there is a problem found in the front office of the Nusa Nipa University Rectorate, namely that the front office has not received special training regarding personal integrity, apart from that there is only one front office staff, so they experience problems if quite a lot of guests come at the same time. From these problems it can be concluded that the personal integrity of front office staff plays a very important role in creating a positive image of the institution, especially in direct interactions with the public, lecturers, students and guests.
ABSTRAKTugas public relations atau humas memiliki peranan penting dalam setiap lembaga karena tugas public relations menjadi salah satu strategi dalam membentuk citra lembaga baik itu citra positif maupun citra negatif. Dalam membentuk citra suatu lembaga, humas biasanya memiliki relasi yang luas untuk itu diperlukan personal integrity. Penelitian ini bertujuan untuk mengetahui bagaimana representasi personal integrity front office dalam tugas humas Universitas Nusa Nipa dan mengetahui hambatan-hambatan pelayanan front office Universitas Nusa Nipa. Penelitian ini menggunakan pendekatan deskriptif kualitatif. Data dikumpulkan dengan wawancara dan observasi. Hasil penelitian ini menunjukan adanya permasalahan yang ditemukan dalam front office Rektorat Universitas Nusa Nipa ialah front office belum mendapatkan pelatihan khusus terkait personal integrity, selain itu staf front office hanya satu orang sehingga mengalami kendala jika tamu yang datang cukup banyak dalam waktu yang bersamaan. Dari permasalahan tersebut dapat disimpulkan bahwa personal integrity staf front office memegang peranan yang sangat penting dalam menciptakan citra positif institusi, khususnya dalam interaksi langsung dengan publik, dosen, mahasiswa dan tamu.
IMPLEMENTASI KURIKULUM MERDEKA MELALUI PEMBELAJARAN BERBASIS PROYEK PADA SEKOLAH PENGGERAK SMPIT AL FITYAN BOARDING SCHOOL BOGOR
Authors: SOPIA SOPIA
Published: January 2025

This study aims to explore the implementation of the Freedom Curriculum through Project-Based Learning (PjBL) at SMPIT Al Fityan Boarding School Bogor. Using a descriptive qualitative approach with a case study design, the research investigates implementation strategies, pedagogical impacts, and student learning experience transformation. Data collection methods include in-depth interviews, participatory observation, and documentation studies involving school principals, teachers, and students. Research results demonstrate that the Freedom Curriculum implementation through PjBL can generate a fundamental transformation in the educational process, developing students' holistic competencies including critical thinking, creativity, collaboration, and learning independence. The study produces a practical model of curriculum implementation that is flexible, student-centered, and responsive to contemporary educational dynamics. The findings provide theoretical and practical contributions in developing innovative pedagogical models aligned with the spirit of learning freedom.
ABSTRAKPenelitian ini bertujuan mengeksplorasi implementasi Kurikulum Merdeka melalui Pembelajaran Berbasis Proyek (PjBL) di SMPIT Al Fityan Boarding School Bogor. Menggunakan pendekatan kualitatif deskriptif dengan desain studi kasus, penelitian menginvestigasi strategi implementasi, dampak pedagogis, dan transformasi pengalaman belajar siswa. Metode pengumpulan data mencakup wawancara mendalam, observasi partisipatif, dan studi dokumentasi dengan melibatkan kepala sekolah, guru, dan siswa. Hasil penelitian menunjukkan bahwa implementasi Kurikulum Merdeka melalui PjBL mampu menghasilkan transformasi fundamental dalam proses pendidikan, mengembangkan kompetensi holistik siswa meliputi kemampuan berpikir kritis, kreativitas, kolaborasi, dan kemandirian belajar. Penelitian menghasilkan model praktis implementasi kurikulum yang fleksibel, berpusat pada siswa, dan responsif terhadap dinamika pendidikan kontemporer. Temuan memberikan kontribusi teoritis dan praktis dalam pengembangan model pedagogis inovatif yang sejalan dengan semangat merdeka belajar.
Combining the U-Net model and a Multi-textRG algorithm for fine SAR ice-water classification
Authors: Sun Yan , Wang Shaoyin , Cheng Xiao , Li Teng , Liu Chong , Ye Yufang , Zhao Xi
Published: January 2025

Abstract. Synthetic Aperture Radar (SAR)-based sea ice classification faces challenges due to the similarity among surfaces such as wind-driven open water (OW), smooth thin ice, and melted ice surfaces. Previous algorithms combine pixel-based and region-based machine learning methods or statistical classifiers, yet struggle with hardly improved accuracy arrested by the fuzzy surfaces and limited manual labels. In this study, we propose an automated algorithm framework by combining the semantic segmentation of ice regions and the multi-stage detection of ice pixels to produce high-accuracy and high-resolution ice-water classification data. Firstly, we used the U-Net convolutional neural networks model with the well processed GCOM-W1 AMSR2 36.5 GHz H polarization, Sentinel-1 SAR EW dual-polarization data, and CIS/DMI ice chart labels as data inputs to train and perform semantic segmentation of major ice distribution regions with near-100 % accuracy. Subsequently, within the U-Net semantically segmented ice region, we redesigned the GLCM textures and the HV/HH polarization ratio of Sentinel-1 SAR images to create a combined texture, which served as the basis for the Multi-textRG algorithm to employ multi-stage region growing for retrieving ice pixel details. We validated the SAR classification results on Landsat-8 and Sentinel-2 optical data yielding an overall accuracy (OA) of 84.9 %, a low false negative (FN) of 4.24 % indicating underestimated low backscatter ice surfaces, and a higher false positive (FP) of 10.8 % reflecting their resolution difference along ice edges. Through detailed analyses and discussions of classification results under the similar ice and water conditions mentioned at the beginning, we anticipate that the proposed algorithm framework successfully addresses accurate ice-water classification across all seasons and enhances the labelling process for ice pixel samples.
Leveraging a time-series event separation method to disentangle time-varying hydrologic controls on streamflow – application to wildfire-affected catchments
Authors: Canham Haley A. , Lane Belize , Phillips Colin B. , Murphy Brendan P.
Published: January 2025

Abstract. Increasing watershed disturbance regimes, such as from wildfire, are a growing concern for natural resource managers. However, the influence of watershed disturbances on event-scale rainfall–runoff patterns has proved challenging to disentangle from other hydrologic controls. To better isolate watershed disturbance effects, this study evaluates the influence of several time-varying hydrologic controls on event-scale rainfall–runoff patterns, including water year type, seasonality, and antecedent precipitation. To accomplish this, we developed the Rainfall–Runoff Event Detection and Identification (RREDI) toolkit, an automated time-series event separation and attribution algorithm that overcomes several limitations of existing techniques. The RREDI toolkit was used to generate a dataset of 5042 rainfall–runoff events from nine western US watersheds. By analyzing this large dataset, water year type and season were identified as significant controls on rainfall–runoff patterns, whereas antecedent moisture was pinpointed as a limited control. Specific effects of wildfire disturbance on runoff response were then demonstrated for two burned watersheds by first grouping rainfall–runoff events based on identified hydrologic controls, such as wet versus dry water year types. The role of water year type and season should be considered in future hydrologic analysis to better isolate the increasing and changing effects of wildfires on streamflow. The RREDI toolkit could be readily applied to investigate the influence of other hydrologic controls and watershed disturbances on rainfall–runoff patterns.
Brief communication: Training of AI-based nowcasting models for rainfall early warning should take into account user requirements
Authors: Ayzel Georgy , Heistermann Maik
Published: January 2025

Abstract. In the field of precipitation nowcasting, deep learning (DL) has emerged as an alternative to conventional tracking and extrapolation techniques. However, DL struggles to adequately predict heavy precipitation, which is essential in early warning. By taking into account specific user requirements, though, we can simplify the training task and boost predictive skill. As an example, we predict the cumulative precipitation of the next hour (instead of 5 min increments) and the exceedance of thresholds (instead of numerical values). A dialogue between developers and users should identify the requirements to a nowcast and how to consider these in model training.
Economic Determinants of Stock Market Volatility in Pakistan: Exploring the Moderating Impact of Political Stability
Authors: Masih Zahid , Irshad Hira
Published: January 2025

The study examines the effect of the variable’s inflation, global oil price index price, and foreign remittances on stock market volatility represented through movement in the KSE 100 index, focusing on political stability as a moderator. The empirical evidence suggests that inflation and the global oil price index reflect insignificant direct influence on the stock market volatility. However, their influence becomes significant in the presence of political stability. Political stability increases investor confidence, reduces risk perception, and mitigates the risk of macroeconomic shocks that lead to reduced stock market volatility. The findings emphasized the critical role of governance in fostering the resilience of the financial market, especially for emerging economies like Pakistan. Future studies could probe further into the sectoral dynamics and consider other alternative variables as moderators, such as institutional quality, to provide detailed insight into the behaviors of stock market performance in developing economies tend to exhibit. These findings have many implications for policymakers, emphasizing governance reforms, stabilization policies of the macroeconomy, and diversification of markets to ensure the financial sector's stability.
Peningkatan Pemahaman dan Keterampilan Perilaku Hidup Bersih dan Sehat (PHBS) pada Siswa Kelas IV SDN Petoran
Authors: Wijayanti Wijayanti , Wianti Sri , Febriyanti Karina
Published: January 2025

Introduction: The practice of Clean and Healthy Lifestyle Behavior (PHBS) among elementary school students still requires attention due to their limited understanding and skills in maintaining personal hygiene, which increases their health risks. Objective: The purpose of this community service was to provide PHBS education to grade IV students at SDN Petoran, Surakarta, using lecture, direct demonstration, and audiovisual media methods. Method: This public service was conducted by engaging 50 students, employing a combination of lectures, direct demonstrations, and audiovisual media to promote PHBS. A pretest and posttest evaluation was conducted to assess the impact of the intervention on the students' understanding and practices. Result: The evaluation results showed a significant improvement in the students' understanding and practices of PHBS, particularly in activities such as handwashing and tooth brushing, which they now perform independently. Paired t-test analysis supported these findings, confirming that the demonstration approach was effective in fostering sustainable healthy habits. Conclusion: This activity is expected to contribute to national efforts to raise health awareness in primary education settings and has the potential to provide long-term health benefits for children.
Cegah dan Kendalikan Hipertensi dengan Tepat untuk Hidup Lebih Lama
Authors: Afiatun Nisa Salsa Zahra , Puadah Farha Tsamrotul , Amalia Keila Rahma , Wati Dewi Neng Mirna , Monika Dhea , J K Ridho Boodie , Reiza Putri Syakila Syalsa , Aprilia Cici , Heryani Heni
Published: January 2025

Introduction: Non-communicable diseases (NCDs) are a major global health threat, contributing to over 36 million deaths annually. Hypertension, a key NCD, is associated with poor health outcomes, including reduced quality of life and increased mortality. This community service is carried out with a prevention strategy as an effort to overcome problems through health education. Health education is not only useful in increasing knowledge but has the potential to change a person's behavior in the long run. Objective: The purpose of this service was to increase public knowledge about hypertension prevention and management to encourage healthy lifestyle practices that reduce the prevalence of hypertension. Method: This public service was conducted at Madrasah At-Thohariyah, Kampung Salaksa, Tasikmalaya, Indonesia, on December 8, 2024. The activities included pre-test and post-test assessments, lectures, discussions, and leaflet distribution to educate participants on hypertension, its risks, and prevention methods. Result: A significant increase in participants' knowledge was evaluated through pre-test and post-test with the percentage of individuals in the good knowledge category increasing from 37.5% (pre-test) to 68.75% (post-test). This increase in knowledge demonstrates the effectiveness of the combination of lectures and leaflets in delivering health education. The positive impact arising from the implementation of community service is clear evidence of the success and achievement of goals. Conclusion: Community education on hypertension through engaging and accessible methods can effectively enhance public awareness and promote behavior changes to prevent and control hypertension.
Cegah Stunting melalui Pendidikan Gizi dan Pelatihan Penyusunan Menu Gizi Seimbang bagi Ibu Balita dan Kader Posyandu
Authors: Kosnayani Ai Sri , Susilowati Prima Endang , Fikrinisa Rizka
Published: January 2025

Introduction: The prevalence of stunting in West Java Province based on data from the 2021 Indonesian Nutritional Status Survey (SSGI) reached 24.5%, above the national average stunting rate of 24.4% and stunting cases in Tasikmalaya City in 2022 were at 14.58% or 6,243. One of the risk factors for stunting is a lack of nutritional intake, especially animal protein. The mother's parenting pattern in providing food is influenced by the mother's knowledge of balanced nutrition rich in animal protein. Providing nutritional counseling using leaflets is expected to increase the mother's knowledge which will lead to a decrease in stunting.
Objective: Reducing the incidence of stunting in toddlers in Kota Baru Village, Cibeureum District, Tasikmalaya City by providing nutritional education using counseling methods assisted by leaflets on balanced nutrition rich in animal protein for mothers of toddlers and integrated health post cadres.
Method: This public service was conducted by providing nutritional education using counseling methods assisted by leaflets regarding balanced nutrition rich in animal protein for mothers of toddlers and integrated health post cadres. Result: there is an increase in the knowledge of mothers of toddlers regarding balanced nutrition rich in animal protein where the first measurement with an average knowledge score of 9.74 and the second measurement with an average knowledge score of 12.43. The p value = 0.000 indicates a significant difference between the average pre and post test values. Conclusion: Providing nutritional counseling assisted by leaflets about balanced nutrition high in animal protein is effective in increasing mothers' knowledge about balanced nutrition rich in animal protein for toddlers.
Comparative effectiveness of microsurgery and endoscopic surgery in lumbar disc herniation: A systematic review and meta-analysis
Authors: Arifin Jainal , Gani Karina Sylvana , Kennedy Dave
Published: January 2025

Lumbar disc herniation, a common degenerative disc disease, adversely affects quality of life and often necessitates surgical intervention. Microsurgery and endoscopic surgery have emerged as alternatives to traditional open surgery, offering reduced pain and shorter recovery times. The aim of this study was to compare the outcomes of microsurgery and endoscopic surgery for lumbar disc herniation, evaluating effectiveness, safety, and patient-reported outcomes. A systematic search was conducted across six databases (EBSCOhost, OVID, ScienceDirect, Scopus, PubMed, and Cochrane) using terms related to lumbar disc herniation, spine injury, minimally invasive biportal endoscopic spine surgery, and conventional microscopic discectomy. The risk of bias was assessed using the Newcastle-Ottawa Scale (NOS), and a random-effects meta-analysis calculated mean differences (MD) and 95% confidence intervals (CI). Among the 267 studies screened, two studies met the inclusion criteria for a meta-analysis assessing the functional outcomes and safety of microsurgery and endoscopic surgery in patients with spinal disorders. The meta-analysis indicated that patients who received microscopic surgery had no significant difference in terms of operation time (MD: 3.48; 95%CI: -14.74 –21.70; p=0.71; I²=90%), postoperative drainage (MD: 16.28; 95%CI: -2.33–34.89; p=0.09; I²=47%), postoperative length of stay (MD: -1.26; 95%CI: -2.52–0.00; p=0.05; I²=77%), and postoperative C-reactive protein (CRP) levels (MD: -13.49; 95%CI: -36.85–9.87; p=0.26; I²= 97%) compared to those treated with endoscopic surgery. In conclusion, microscopic surgery and endoscopic surgery yield similar outcomes in terms of operation time, postoperative drainage, postoperative length of stay, and postoperative CRP levels. Therefore, the choice of techniques should be guided by patient-specific factors, surgeon expertise, and the facilities available at the healthcare center.
KOMPAK: Translation, cross-cultural adaptation, and validation of an instrument for assessing interprofessional collaboration between pharmacists and physicians in Indonesia
Authors: Amin Irnawati H. , Massi Muhammad N. , Wahyudin Elly , Bahar Muhammad A. , Hadju Veni , Niamuzisilawati Eva , Munawwaroh Makiyatul , Utami Ikrimah N. , Ardiansyah Akhmad , Alkaff Sylmina D. , Arifin Bustanul
Published: January 2025

Interprofessional collaboration is crucial for addressing the complexity of health problems, requiring contributions from various professions to enhance healthcare quality, improve patient satisfaction, and achieve better clinical outcomes. The aim of this study was to develop and validate the physicians and pharmacists collaborative practice instrument, known as KOMPAK (Kolaborasi Medis Persepsi Apoteker dan Dokter/Medical Collaboration: Perceptions of Pharmacists and Physicians) for use in Indonesia. A cross-sectional study was conducted across the western, central, and eastern rigors of Indonesia, targeting physicians and pharmacists. The study included translation (forward and backward), cross-cultural adaptation (with 30 participants), and validation using confirmatory factor analysis (CFA) among 315 physicians and 315 pharmacists. The present study found no significant changes emerged during the translation and adaptation phases. In the validation phase, the CFA results for the physician instrument indicated a Comparative Fit Index (CFI) of 0.94 (>0.92), Tucker-Lewis Index (TLI) of 0.93 (>0.92), Root Mean Squared Error of Approximation (RMSEA) of 0.055 (<0.07), Standardized Root Mean Residual (SRMR) of 0.07 (<0.08), and Cronbach’s Alpha reliability of 0.88. The pharmacist instrument yielded similar results with a CFI of 0.94 (>0.92), TLI of 0.93 (>0.92), RMSEA of 0.06 (<0.07), SRMR of 0.05 (<0.08), and Cronbach’s Alpha reliability of 0.83. The final instrument consists of 24 items. In conclusion, the KOMPAK instrument demonstrated validity and reliability, supporting its use for measuring interprofessional collaboration between physicians and pharmacists in Indonesia.
Occupational risk factors related to musculoskeletal disorders among Praewa silk weavers in the Northeast region, Thailand
Authors: Yota Wuttichai , Neubert Manida S. , Kaewdok Teeraphun
Published: January 2025

Praewa silk weavers are subject to numerous occupational risk factors that contribute to musculoskeletal disorders (MSDs), primarily due to inadequate occupational safety measures, limited access to health services, and substandard working conditions. The aim of this study was to assess the prevalence rate and determinants of MSDs among Praewa silk weavers. A cross-sectional study employing a convenience sampling method was conducted, involving 198 Praewa silk weavers from four provinces in the Northeast region of Thailand. Data collection was facilitated through a two-part research tool. The first part included a questionnaire assessment using demographic information, workplace conditions, and self-reported MSDs. The second part involved an ergonomic risk assessment using rapid upper limb assessment (RULA) and hand activity level (HAL). Descriptive statistics and multiple logistic regression analyses were conducted to determine the prevalence and associated factors of MSDs among participants. The findings revealed that the prevalence rates of MSDs in the past 7 days and 12 months were 68.68% and 96.46%, respectively. The highest prevalence rates of MSDs (over 60.00%) were observed in the wrists, fingers, and neck, with similar trends reported in both the past 7 days and 12 months. Key factors associated with MSDs over the past 12 months included low hand strength test results (adjusted odds ratio (AOR)=2.09; 95%CI: 0.44–11.05), quite low hand strength test results (AOR=2.49; 95%CI: 0.29–21.15), weaving experience of 21–30 years (AOR=1.07; 95%CI: 0.20–5.64), age between 31–40 years  (AOR=2.63; 95%CI: 0.49–13.91), age above 41 years (AOR=1.13; 95%CI: 1.08–1.19), RULA level 4 (AOR=3.62; 95%CI: 0.66–19.96), and HAL score exceeding 0.78 (AOR=0.63; 95%CI: 0.80–0.98) were significantly associated with MSDs during the past 12 months. This study highlights the high prevalence of MSDs among Praewa silk weavers, attributed to occupational risk factors such as low hand strength, high hand activity level, extensive weaving experience, and poor working posture. The weaving process itself is a significant contributor to these disorders. In conclusion, ergonomics interventions aimed at preventing MSDs, including postural training, injury prevention programs, and re-designed pull-cloth devices, are recommended to mitigate these risks.
Exploring factors contributing to falls in home-dwelling older adults: A cross-sectional study in Northeastern Thailand
Authors: Boonkhao Laksanee , Choochouy Nattagorn , Rattanachaikunsopon Pongsak , Laosupap Kitti , Saenrueang Thitima , Labcom Chiraporn , Chakhamrun Nittaya , Boonsang Arun , Butsorn Aree
Published: January 2025

Falls are the most common accidents among older adults in home settings. Older adults experience falls due to several risk factors. In 2005, Thailand became an aging society, with projections indicating that by 2021, older adults would represent the majority of the population, and by 2035, approximately 30 percent of the population would be older adults. Approximately 3 million fall episodes transpire among older adults each year in Thailand, leading to almost 60,000 hospitalizations. The aim of this study was to examine the factors associated with falls among older adults in northeastern Thailand, hypothesizing that characteristics such as cognitive capacity, visual acuity, hearing acuity, balance ability, and mobility are associated with fall risk in this population. A cross-sectional analytical study involved 264 older adults aged 60 years or older using a questionnaire and a battery of tests that assessed the participants’ cognitive capacity, eyesight proficiency, hearing ability, balancing ability, and mobility. The variables that exhibited a statistically significant association (p<0.05) were employed in a binary logistic regression analysis. The results revealed that falls among home-living older adults were significantly associated with sex, family size, congenital issues, and mobility. Older adults who were female and had a large family, congenital disorders, or mobility impairments were at a higher risk of falls, which emphasizes the need for personalized prevention strategies. It is recommended to adopt a proactive healthcare strategy to prevent falls and ensure safe living conditions. Interventions aimed at improving balance, mobility, and mental health, as well as encouraging an active lifestyle, may reduce the risk of falls among older adults living in the community. The findings may aid private and government agencies in developing effective fall prevention programs for older adults living at home.
Impact of Antibodies Against the Zinc Transporter 8 (ZnT8) on the Morphotic Elements of Peripheral Blood - Preliminary Report.
Authors:   Clinical Department of Haematology, Haematological Oncology and Internal Medicine, Regional Hospital in Opole, Faculty of Medicine, University of Opole, Opole, Poland., Tubek Sławomir
Published: January 2025

The variability in the expression of the gene for the zinc
membrane transporter ZnT8 in leukocytes - on the one hand,
and the presence of antibodies against this transporter,
at a level of 5-6% in the adult population over 30 years of
age, on the other - raises the question of the biological and
clinical significance of the potential coincidence of these
phenomena.
Material and method: It was decided to retrospectively
evaluate the relationship between the presence of the
serum anti-ZnT8 antibodies (ZnT8Ab) and the parameters of
complete blood counts.
Within the period 06/2023 - 04/2024 - 216 ZnT8Ab
determinations were performed, mainly in patients in the
diabetology department (in patients with type 2 diabetes), of
which 15 patients were higher or equal to 10 RU/ml - which
represented 7% of the study group of patients.
Results: On the basis of the available data, it can be
concluded that the high ZnT8Ab values could be linked
to an increased susceptibility to haemolysis, haemolytic
anaemia and changes in other morphotic parameters of
the peripheral blood - a tendency to lower lymphocyte and
platelet levels. That is, the presence of ZnT8Ab could be one
of the factors leading to thrombocytopenia and impaired
cellular immunity. The retrospective analysis of the data
presented here - suggests that high ZnT8Ab values may
result in a greater tendency for changes in blood morphotic
elements - including erythrocyte, platelet and leukocyte
counts (including neutrocytes and lymphocytes) - in the
directions observed in the aforementioned analyses. The
decrease in platelet count was accompanied by an increase in
platelet anisocytosis, while the decrease in leukocytes involved
both neutrocytes and lymphocytes. Generally, all quantitative
blood count parameters studied showed declining trends.
Conclusions: Generally, in the current study, all quantitative
blood morphotic parameters tested tended to decrease with
the increasing levels of ZnT8Ab.
Defining coordinates of the transdisciplinary framework
Authors:   Ion Creangă Pedagogical State University, APREOTESEI Maria Diana
Published: January 2025

Interdisciplinarity and transdisciplinarity are two of the four arrows of one and the same bow: that of knowledge.The complex and integrated nature of problems such as globalization, migration, interculturality, environmental protection, information explosion, poverty, conflicts, etc. claims a transdisciplinary approach.
Psychological interventions in reducing loneliness in the elderly: effectiveness of the training program
Authors:   Ion Creangă Pedagogical State University, DIȚĂ Iris Ionelia
Published: January 2025

In the context of an aging population, loneliness among the elderly has emerged as a major public health concern, with significant negative effects on both mental and physical health. Older adults frequently face post-retirement stress, depression due to the loss of loved ones, and anxiety driven by material and health-related uncertainties. These factors not only exacerbate chronic psychological disorders but also contribute to increased social isolation and a decline in quality of life. The literature highlights a significant correlation between loneliness, socio-demographic variables, and various negative emotional states, such as anxiety, depression, and stress, while also underscoring the considerable impact on personality and quality of life. This study presents a psychological intervention program designed to reduce loneliness among the elderly, based on a multidimensional approach that integrates cognitive-behavioral techniques, rational-emotive therapy, reminiscence therapy, and art therapy. The program was tested on a sample of 24 elderly individuals, randomly assigned to experimental and control groups. The results, obtained through a comparative experimental design, demonstrate a significant reduction in depression, anxiety, and stress among participants in the intervention group, emphasizing the importance of implementing such programs to improve the quality of life for the elderly.
Pedagogical experiences of valuing ict in continuous training of evaluation competence of teaching staff
Authors:   Ion Creangă Pedagogical State University, CHINDRIS Claudiu
Published: January 2025

The praxiological foundation of the e-education system of the continuous training of the teaching staff from the perspective of developing professional competence is in accordance with European and national policies and aims at: • ensuring the freedom and rights to choose from of continuous e-learning training from the perspective of life long education; • training developing digital competence stipulated in the Education Code; • streamlining the educational and management process through the use of ICTȘ • ensuring the compatibility of the education in the Republic of Moldova with the European modern era through adaptation to ,,e-European information society for all „strategy”; • conceptualizing social development based on an innovative, open, competitive education, changing the techno- logical equipment infrastructure of both continuous education centres, as well as the institutions providing such services, which also become service providers with the use of also become service providers with the use of ITC.
Characterization and synthetic biology elements of nonmodel bacteria, Acetobacteraceae
Authors: Gao Yanmei ,   Province Hefei National Laboratory for Physical Sciences at the Microscale, University of Science and Technology of China, Hefei 230026, China
Published: January 2025

Acetobacteraceae has garnered significant attention because of its unique properties and the broad applications of the bacterial cellulose it produces. However, unlike model strains, Acetobacteraceae have few synthetic biology applications because they are difficult to manipulate genetically and have insufficient genetic regulatory elements, among other factors. To address this limitation, this study characterized the fundamental properties and synthetic biology elements of three commonly used bacterial cellulose-producing strains. First, the basic characteristics of the three strains, including their cellulose film production ability, division time, antibiotic susceptibility, and plasmid features, were analyzed. Two inducible promoters (pTrc and pLux101) were subsequently characterized within the three strains. The inducibility of the pTrc promoter was relatively low across the three strains (induction ratio: 1.98–6.39), whereas the pLux101 promoter demonstrated a significantly greater level of inducibility within the three strains (induction ratio: 87.28–216.71). Finally, through gene knockout experiments, this study identified four genes essential for bacterial cellulose film production in the genome of the Gluconacetobacter hansenii ATCC 5358 strain. This study not only enriches the library of synthetic biology elements in nonmodel strains, but also lays the foundation for the synthetic biology applications of Acetobacteraceae.
Remote electron effects and π-π interactions of α-diimine nickel complexes
Authors: Wang Yizhan , He Hailong , Peng Dan ,   Hefei National Research Center for Physical Sciences at the Microscale, CAS Key Laboratory of Soft Matter Chemistry, Department of Polymer Science and Engineering, University of Science and Technology of China, Hefei 230026, China
Published: January 2025

The seminal report of α-diimine palladium and nickel catalysts in 1995 represented a major breakthrough in the preparation of functionalized polyolefin materials. Owing to the high abundance and low cost of nickel, nickel-based catalysts have great application prospects in the industrialization process of olefin coordination polymerization. In this work, various N-aryl substituents with different electronic effects were synthesized and introduced into α-diimine ligands. The as-prepared α-diimine nickel catalysts showed high polymerization activity (0.9×107–3.0×107 g·mol−1·h−1) in ethylene polymerization, generating polyethylene products with adjustable molecular weights (Mn values: 7.4×104–146.9×104 g·mol−1) and branching densities (31/1000 C–68/1000 C). The resulting polyethylene products showed excellent mechanical properties, with high tensile strength (up to 25.0 MPa) and high strain at break values (up to 3890%). The copolymerization of ethylene and polar monomers can also be achieved by these nicekel complexes, ultimately preparing functionalized polyolefins.
A novel missense mutation in QRICH2 causes male infertility due to multiple morphological abnormalities of the sperm flagella
Authors: Raza Yousaf , Zhang Huan , Zubair Muhammad , Hussain Ansar , Ahmad Nisar , Chen Min , Yang Gang , Abbas Musavir , Abbas Tanveer , Shoaib Muhammad , Mustafa Ghulam , Ali Imtiaz , Uddin Meftah , Fan Suixing , Shah Wasim , Shi Qinghua ,   Center for Reproduction and Genetics, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, Biomedical Sciences and Health Laboratory of Anhui Province, Institute of Health and Medicine, Hefei Comprehensive National Science Center, University of Science and Technology of China, Hefei 230027, China
Published: January 2025

Multiple morphological abnormalities of the sperm flagella (MMAF) are characterized by bent, irregular, short, coiled, and absent flagella. MMAF is caused by a variety of genes, some of which have been identified. However, the underlying genetic factors responsible for the majority of MMAF cases are still largely unknown. The glutamine-rich 2 (QRICH2) gene plays an essential role in the development of sperm flagella by regulating the expression of essential sperm flagellar biogenesis-associated proteins, and genetic variants of QRICH2 have been identified as the primary cause of MMAF in humans and mice. Here, we recruited a Pakistani consanguineous family to identify the genetic variant causing infertility in patients with MMAF. Whole-exome sequencing and Sanger sequencing were conducted to identify potentially pathogenic variants causing MMAF in infertile patients. Hematoxylin and eosin (HE) staining was performed to analyze sperm morphology. Quantitative polymerase chain reaction, western blot, and immunofluorescence staining analyses were conducted to observe the expression of QRICH2 in spermatozoa. A novel homozygous missense variant (c.4618C>T) in QRICH2 was identified in the affected patients. Morphological analysis of spermatozoa revealed the MMAF phenotype in infertile patients. qPCR revealed a significant reduction in the level of sperm QRICH2 mRNA, and immunofluorescence staining revealed a lack of sperm QRICH2 expression. Additionally, patients harboring a homozygous QRICH2 mutation presented reduced expression of outer dense fiber 2 (ODF2) in sperm, whereas sperm expression of A-kinase anchor protein 4 (AKAP4) was normal. These findings expand our understanding of the genetic causes of MMAF-associated male infertility and emphasize the importance of genetic counseling.
Enhanced photocatalytic CO2 reduction performance in Ni-doped perovskite nanocrystals controlled by magnetic fields
Authors: Zhang Zhiwen , Zhang Haoran , Zhou Huang , Zhang Yu , Wu Yuen ,   Key Laboratory of Precision and Intelligent Chemistry, School of Chemistry and Materials Science, University of Science and Technology of China, Hefei 230026, China,   Deep Space Exploration Laboratory, University of Science and Technology of China, Hefei 230026, China
Published: January 2025

In recent years, magnetic fields have been widely applied in catalysis to increase the performance of electrocatalysis, photocatalysis, and thermocatalysis through an important noncontact way. This work demonstrated that doping CsPbCl3 halide perovskite nanocrystals with nickel ions (Ni2+) and applying an external magnetic field can significantly enhance the performance of the photocatalytic carbon dioxide reduction reaction (CO2RR). Compared with its counterpart, Ni-doped CsPbCl3 exhibits a sixfold increase in CO2RR efficiency under a 500 mT magnetic field. Insights into the mechanism of this enhancement effect were obtained through photogenerated current density measurements and X-ray magnetic circular dichroism. The results illustrate that the significant enhancement in catalytic performance by the magnetic field is attributed to the synergistic effects of magnetic element doping and the external magnetic field, leading to reduced electron‒hole recombination and extended carrier lifetimes. This study provides an effective strategy for enhancing the efficiency of the photocatalytic CO2RR by manipulating spin-polarized electrons in photocatalytic semiconductors via a noncontact external magnetic field.
Unusual Stroke Presentations: A Review of Reported Cases
Authors: Alabdulmohsen Dalal Mahmoud
Published: January 2025

Stroke is a major cause of death and disability, primarily due to ischemic events. While common symptoms are well-known, stroke can present atypically, making diagnosis difficult. Early recognition of these uncommon presentations is crucial, as delays in diagnosis can lead to permanent damage or death, highlighting the importance of thorough evaluation in emergency situations. This study explores the challenges of recognizing stroke with atypical initial manifestations. A literature review of case reports revealed that stroke patients may present with atypical complaints, including acute hearing loss, isolated ptosis, continuous cough, foreign-body sensation in the throat, sleep disturbance, chest pain, limb pain, foot drop, psychosis, and others. These unusual presentations can misdirect the diagnostic process, leading to delayed stroke diagnosis and potentially serious consequences. By examining these cases, the importance of maintaining a high index of suspicion for stroke is emphasized, even in the absence of classic neurological signs. Early recognition and timely intervention, supported by thorough neurological assessments and appropriate imaging, are essential for improving patient outcomes and reducing neurological damage.

Key words: Stroke, Stroke chameleons, Diagnostic challenges, Neurology review
Pobaltské štáty v 20. storočí a ich cesta k nezávislosti
Authors: Daniš Martin
Published: January 2025

The aim of the work is to analyze historical development of the Baltic states in 20th century and their road to independence. During the 20th century the Baltic states (Estonia, Latvia and Lithuania) went through various developments and were part of various state entities in the mentioned period. Due to their geographical location, the Baltic states are located between Germany and Russia, that is, states that were direct participants in the 1st and 2nd world wars, and their mutual military clash also took place on the territory of the Baltic states. With the exception of a short period in the 1920s and 1930s, the Baltic states were occupied by Germany or Russia. However, the effort of the Baltic States was to gain independence, which was achieved only after the collapse of the Soviet Union in 1991. However, after the collapse of the Soviet Union, the Baltic States continued to face the efforts of the Russian Federation, whose efforts were to ensure continued influence on their territory By analyzing individual periods of the historical development of the Baltic states, it was found that the efforts of the Russian Federation to maintain influence over the Baltic states were not successful due to the pro-Western orientation of the Baltic states and their legitimate ambition to become members of the European Union and NATO.
Paradigmy vedecko-pedagogickej činnosti v oblasti sociológie vojny, armády a bezpečnosti
Authors: Martinská Mária , Matis Jozef
Published: January 2025

The article contains a brief analysis of the development of scientific and pedagogical activities of associate professor Jozef Matis who celebrates his 70th birthday this year. Until 2018, he was the head of the Department of Social Sciences and Languages of the Armed Forces Academy of General Milan Rastislav Štefánik in Liptovský Mikuláš. His scientific and pedagogical activities are focused on sociology of security, war and the army, with an emphasis on the processes of shaping a security manager in general and a military professional in particular from a sociological and andragogical point of view.
Biện pháp quản lý hoạt động tự đánh giá trong kiểm định chất lượng giáo dục của các trường tiểu học huyện Cần Giuộc, tỉnh Long An
Authors: Phan Trọng Nam , Ngô Trần Nghĩa
Published: January 2025

Hoạt động tự đánh giá trong kiểm định chất lượng giáo dục là thành phần quan trọng giúp đảm bảo và nâng cao chất lượng giáo dục tại các trường tiểu học. Bài báo phân tích thực trạng quản lý hoạt động tự đánh giá tại các trường tiểu học huyện Cần Giuộc, tỉnh Long An, bao gồm nhận thức của cán bộ quản lý và giáo viên, quy trình thực hiện, cùng các yếu tố ảnh hưởng. Kết quả nghiên cứu chỉ ra nhiều hạn chế, như: một bộ phận cán bộ quản lý và giáo viên chưa nhận thức đầy đủ về mục tiêu, nội dung và quy trình tự đánh giá; chưa phát huy tốt sức mạnh tập thể trong nhà trường; lập kế hoạch và phân bổ nguồn lực còn thiếu đồng bộ; cơ sở vật chất và thiết bị dạy học chưa đáp ứng nhu cầu; quan hệ giữa nhà trường, gia đình và xã hội còn lỏng lẻo; công tác chuyên môn kiểm định chưa sâu, dẫn đến đánh giá tiêu chí chưa đảm bảo quy trình.Bài báo đề xuất 5 biện pháp quản lý để khắc phục các hạn chế này: Nâng cao nhận thức cho cán bộ quản lý và giáo viên về vai trò, mục tiêu và nội dung tự đánh giá; Thực hiện thường xuyên và hiệu quả các nội dung tự đánh giá, bám sát các tiêu chuẩn; Chỉ đạo chặt chẽ việc đánh giá các tiêu chí, đảm bảo tính chính xác và phù hợp; Huy động sức mạnh tập thể trong nhà trường để tạo sự đồng thuận và phối hợp; Tận dụng hiệu quả các nguồn lực từ bên ngoài nhằm cải thiện cơ sở vật chất và điều kiện phục vụ hoạt động tự đánh giá. Những biện pháp này hướng đến việc nâng cao hiệu quả tự đánh giá, cải tiến và phát triển chất lượng giáo dục, góp phần thực hiện thành công mục tiêu đổi mới giáo dục toàn diện tại địa phương.
Transforming Marfan Syndrome Diagnosis with AI and Federated Learning
Authors:   Department of Computing, Glasgow Caledonian University, Glasgow G4 0BA, Scotland., Upadrista Venkatesh
Published: January 2025

Marfan Syndrome is a genetic disorder affecting connective tissue, leading to severe cardiovascular, skeletal, and ocular complications.
The Role of Beta Adrenergic Receptor on Epinephrine induced Metastasis in Breast Cancer
Authors:   Institute of Queen Elizabeth Hospital Birmingham, Birmingham, United Kingdom., Hassan Ali
Published: January 2025

I am writing this letter to bring your concern on The role of beta adrenergic receptor on epinephrine induced metastasis in breast cancer.
Projekt naukowy „Ciągłość i zmiana. Sto lat rozwoju polskiej wsi” realizowany przez Instytut Rozwoju Wsi i Rolnictwa PAN – informacja i zaproszenie
Authors: Wilkin Jerzy
Published: January 2025

Inspiracją do podjęcia się przygotowania wszechstronnej syntezy naukowej ewolucji wsi i rolnictwa w Polsce, jej mechanizmów, prawidłowości i efektów, analizowanych w długiej perspektywie czasowej, jest przypadająca w 2018 r. stuletnia rocznica odzyskania przez nasz kraj niepodległości po okresie zaborów. Wspomniane stulecie jest dla badaczy społecznych fascynującym okresem zmian we wszystkich dziedzinach życia, w tym fundamentalnych przemian systemowych. Wieś i rolnictwo odegrały w tych przemianach bardzo ważną rolę. Tytułowy projekt naukowy ma charakter interdyscyplinarny, integrujący dorobek ekonomii, socjologii, demografii, historii, politologii, geografii i innych nauk.