bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figures 1 - 13 from SIRT1 Limits the Function and Fate of Myeloid-Derived Suppressor Cells in Tumors by Orchestrating HIF-1α–Dependent Glycolysis
Authors: Liu Guangwei , Bi Yujing , Shen Bo , Yang Hui , Zhang Yan , Wang Xiao , Liu Huanrong , Lu Yun , Liao Jiongbo , Chen Xi , Chu Yiwei
Published: March 2023

PDF file - 436K, Fig.S1. MDSC polarizing differentiation condition alters glycolytic activity. Fig.S2.MDSC SIRT1 expansions in spleen and tumor of SIRT1KO and WT-bearing tumor mice. Fig.S3.SIRT1 deficiency MDSCs showed normal cell death and proliferation. Fig.S4.SIRT1 is required for MDSC polarization. Fig.S5.Characterization of surface marker of bone marrow-derived MDSCs. Fig.S6.SIRT1 intrinsicly controls the function and differentiation of tumor MDSCs. Fig.S7.The potentiating killing activity of SIRT1-/- MDSCs is associated with the higher glycolytic activity. Fig.S8.CD115+ monocytic MDSC effects in tumor killing. Fig.S9.SIRT1 deficiency from MDSCs could not alter the activation of NF-κB signaling after LPS treatment. Fig.S10.SIRT1-dependent MDSC glycolytic activity changes are associated with mTOR-HIF1α pathway. Fig.S11.SIRT-HIF axis directs the function and fate of MDSC associated with glycolytic activity. Fig.S12.SIRT-HIF axis potentiates glycolytic activity and tumor killing ability. Fig.S13.SIRT1 masters MDSC function and fate in tumor through mTOR/HIF1α dependent glycolytic pathway.
Supplementary Methods from VISTA Regulates the Development of Protective Antitumor Immunity
Authors: Le Mercier Isabelle , Chen Wenna , Lines Janet L. , Day Maria , Li Jiannan , Sergent Petra , Noelle Randolph J. , Wang Li
Published: March 2023

PDF file - 90K, Description of additional methods and procedures used in the study.
Supplementary Table 2 from Survival in Patients with High-Risk Prostate Cancer Is Predicted by miR-221, Which Regulates Proliferation, Apoptosis, and Invasion of Prostate Cancer Cells by Inhibiting IRF2 and SOCS3
Authors: Kneitz Burkhard , Krebs Markus , Kalogirou Charis , Schubert Maria , Joniau Steven , van Poppel Hein , Lerut Evelyne , Kneitz Susanne , Scholz Claus Jürgen , Ströbel Philipp , Gessler Manfred , Riedmiller Hubertus , Spahn Martin
Published: March 2023

XLSX file - 90K, List of up and downregulated genes.
Supplementary Figure 6 from VISTA Regulates the Development of Protective Antitumor Immunity
Authors: Le Mercier Isabelle , Chen Wenna , Lines Janet L. , Day Maria , Li Jiannan , Sergent Petra , Noelle Randolph J. , Wang Li
Published: March 2023

PDF file - Better long-term survival was achieved with a prime-boost vaccine regime when treating 7-day B16-BL6 melanoma in combination with VISTA mab (13F3).
Supplementary Figure 2 from VISTA Regulates the Development of Protective Antitumor Immunity
Authors: Le Mercier Isabelle , Chen Wenna , Lines Janet L. , Day Maria , Li Jiannan , Sergent Petra , Noelle Randolph J. , Wang Li
Published: March 2023

PDF file - 7K, VISTA mab did not directly alter the proliferation and apoptosis of tumor cells.
Supplementary Figure 1 from Survival in Patients with High-Risk Prostate Cancer Is Predicted by miR-221, Which Regulates Proliferation, Apoptosis, and Invasion of Prostate Cancer Cells by Inhibiting IRF2 and SOCS3
Authors: Kneitz Burkhard , Krebs Markus , Kalogirou Charis , Schubert Maria , Joniau Steven , van Poppel Hein , Lerut Evelyne , Kneitz Susanne , Scholz Claus Jürgen , Ströbel Philipp , Gessler Manfred , Riedmiller Hubertus , Spahn Martin
Published: March 2023

PDF file - 27K, Flow charts demonstrating the patient selection.
Supplementary Figure 6 from Metastatic Consequences of Immune Escape from NK Cell Cytotoxicity by Human Breast Cancer Stem Cells
Authors: Wang Bin , Wang Qiang , Wang Zhe , Jiang Jun , Yu Shi-Cang , Ping Yi-Fang , Yang Jing , Xu Sen-Lin , Ye Xian-Zong , Xu Chuan , Yang Lang , Qian Cheng , Wang Ji Ming , Cui You-Hong , Zhang Xia , Bian Xiu-Wu
Published: March 2023

Suppression of MICA/B by overexpressing miR-20a in BCSCs.
Supplementary Figure 4 from Metastatic Consequences of Immune Escape from NK Cell Cytotoxicity by Human Breast Cancer Stem Cells
Authors: Wang Bin , Wang Qiang , Wang Zhe , Jiang Jun , Yu Shi-Cang , Ping Yi-Fang , Yang Jing , Xu Sen-Lin , Ye Xian-Zong , Xu Chuan , Yang Lang , Qian Cheng , Wang Ji Ming , Cui You-Hong , Zhang Xia , Bian Xiu-Wu
Published: March 2023

Differential expression of the ligands for NK cell inhibitory and stimulatory receptor by BCSCs or non-BCSCs.
Supplementary Figure 4 from FANCJ Localization by Mismatch Repair Is Vital to Maintain Genomic Integrity after UV Irradiation
Authors: Guillemette Shawna , Branagan Amy , Peng Min , Dhruva Aashana , Schärer Orlando D. , Cantor Sharon B.
Published: March 2023

PDF file - 68K, Supplemental Figure 4. FANCJ and MMR function in a common pathway for RPA phosphorylation and 6-4 Photoproduct elimination, but not for gap repair.
Supplementary Figure Legend from GPR56 Inhibits Melanoma Growth by Internalizing and Degrading Its Ligand TG2
Authors: Yang Liquan , Friedland Scott , Corson Nancy , Xu Lei
Published: March 2023

PDF file - 55K
Supplementary Figure 1 from FANCJ Localization by Mismatch Repair Is Vital to Maintain Genomic Integrity after UV Irradiation
Authors: Guillemette Shawna , Branagan Amy , Peng Min , Dhruva Aashana , Schärer Orlando D. , Cantor Sharon B.
Published: March 2023

PDF file - 151K, Supplemental Figure 1. FANCJ is recruited to sites of UV-induced damage in an NER dependent manner
Supplementary Figure 6 from GPR56 Inhibits Melanoma Growth by Internalizing and Degrading Its Ligand TG2
Authors: Yang Liquan , Friedland Scott , Corson Nancy , Xu Lei
Published: March 2023

PDF file - 404K, This figure shows that TG2 internalization is similarly regulated by GPR56 in WM115 cells.
Supplementary Figure 8 from Inhibition of miR-17 and miR-20a by Oridonin Triggers Apoptosis and Reverses Chemoresistance by Derepressing BIM-S
Authors: Weng Hengyou , Huang Huilin , Dong Bowen , Zhao Panpan , Zhou Hui , Qu Lianghu
Published: March 2023

PDF file - 41KB, Oridonin sensitizes leukemia cells to VP-16.
Supplementary Figure 5 from GPR56 Inhibits Melanoma Growth by Internalizing and Degrading Its Ligand TG2
Authors: Yang Liquan , Friedland Scott , Corson Nancy , Xu Lei
Published: March 2023

PDF file - 211K, This figure shows that the cytosolic fraction of TG2 is not affected by GPR56 expression.
Supplementary Figure 7 from Inhibition of miR-17 and miR-20a by Oridonin Triggers Apoptosis and Reverses Chemoresistance by Derepressing BIM-S
Authors: Weng Hengyou , Huang Huilin , Dong Bowen , Zhao Panpan , Zhou Hui , Qu Lianghu
Published: March 2023

PDF file - 21KB, Oridonin has no synergic effect with Ara-C.
Supplementary Figure 6 from Inhibition of miR-17 and miR-20a by Oridonin Triggers Apoptosis and Reverses Chemoresistance by Derepressing BIM-S
Authors: Weng Hengyou , Huang Huilin , Dong Bowen , Zhao Panpan , Zhou Hui , Qu Lianghu
Published: March 2023

PDF file - 45KB, Inhibition of miR-17 or miR-20a has little effect on the sensitivity of K562 to Ara-C.
Supplementary Figure 2 from GPR56 Inhibits Melanoma Growth by Internalizing and Degrading Its Ligand TG2
Authors: Yang Liquan , Friedland Scott , Corson Nancy , Xu Lei
Published: March 2023

PDF file - 439K, This figure contains grow curves of various cell lines used in the manuscript.
Supplementary Figure 1 from GPR56 Inhibits Melanoma Growth by Internalizing and Degrading Its Ligand TG2
Authors: Yang Liquan , Friedland Scott , Corson Nancy , Xu Lei
Published: March 2023

PDF file - 160K, This figure illustrates the direct binding between GPR56 an human TG2.
Supplementary Table 3 from High Fidelity Patient-Derived Xenografts for Accelerating Prostate Cancer Discovery and Drug Development
Authors: Lin Dong , Wyatt Alexander W. , Xue Hui , Wang Yuwei , Dong Xin , Haegert Anne , Wu Rebecca , Brahmbhatt Sonal , Mo Fan , Jong Lina , Bell Robert H. , Anderson Shawn , Hurtado-Coll Antonio , Fazli Ladan , Sharma Manju , Beltran Himisha , Rubin Mark , Cox Michael , Gout Peter W. , Morris James , Goldenberg Larry , Volik Stanislav V. , Gleave Martin E. , Collins Colin C. , Wang Yuzhuo
Published: March 2023

XLSX file - 12K, Supplementary Table 3: Clinical information of grafted cases.
Supplementary Figure 5 from Inducible Nitric Oxide Synthase Drives mTOR Pathway Activation and Proliferation of Human Melanoma by Reversible Nitrosylation of TSC2
Authors: Lopez-Rivera Esther , Jayaraman Padmini , Parikh Falguni , Davies Michael A. , Ekmekcioglu Suhendan , Izadmehr Sudeh , Milton Denái R. , Chipuk Jerry E. , Grimm Elizabeth A. , Estrada Yeriel , Aguirre-Ghiso Julio , Sikora Andrew G.
Published: March 2023

PDF file - 135K, A375 melanoma cells were exposed for 6 hours or 24 Hours to ODQ (3 uM, 10 uM), or the vehicle control dimethylsulfoxide (DMSO). mTOR pathway activation was analyzed by 4EBP1 and p-S6RP western blot. Signals were quantified by densitometry, and the ratio of activated p-4EBP1 and p-S6RP was calculated, normalized against total protein (lower panel). ODQ even at extended time point (24 hours) and high dose (10 uM) had little effect on mTOR pathway activation.
Supplementary Figure 3 from Inducible Nitric Oxide Synthase Drives mTOR Pathway Activation and Proliferation of Human Melanoma by Reversible Nitrosylation of TSC2
Authors: Lopez-Rivera Esther , Jayaraman Padmini , Parikh Falguni , Davies Michael A. , Ekmekcioglu Suhendan , Izadmehr Sudeh , Milton Denái R. , Chipuk Jerry E. , Grimm Elizabeth A. , Estrada Yeriel , Aguirre-Ghiso Julio , Sikora Andrew G.
Published: March 2023

PDF file - 77K, A375 cells were cultured with the indicated concentrations of the NO donor S-nitroso-acetyl-penicillamine (SNAP), or the NO scavenger PTIO for 16 Hours prior to harvest and preparation of protein lysates.. Biotin switch assay was performed as described in Figure 6, and immunoblotting for BCL-2 and AKT performed after streptavidin pull-down to determine nitrosylated levels of these proteins.
Supplementary Figure 2 from Inducible Nitric Oxide Synthase Drives mTOR Pathway Activation and Proliferation of Human Melanoma by Reversible Nitrosylation of TSC2
Authors: Lopez-Rivera Esther , Jayaraman Padmini , Parikh Falguni , Davies Michael A. , Ekmekcioglu Suhendan , Izadmehr Sudeh , Milton Denái R. , Chipuk Jerry E. , Grimm Elizabeth A. , Estrada Yeriel , Aguirre-Ghiso Julio , Sikora Andrew G.
Published: March 2023

PDF file - 76K, In MT-RET-1 mouse melanoma cell line we transient trafected with with siRNA-iNOS human, after 48 hours MT-RET-1 mouse cell lysate were subjected to SDS-PAGE and western blot analysis for iNOS, and actin as a loading control.
Supplementary Figure S1 from Whole-Genome Sequencing of Asian Lung Cancers: Second-Hand Smoke Unlikely to Be Responsible for Higher Incidence of Lung Cancer among Asian Never-Smokers
Authors: Krishnan Vidhya G. , Ebert Philip J. , Ting Jason C. , Lim Elaine , Wong Swee-Seong , Teo Audrey S.M. , Yue Yong G. , Chua Hui-Hoon , Ma Xiwen , Loh Gary S.L. , Lin Yuhao , Tan Joanna H.J. , Yu Kun , Zhang Shenli , Reinhard Christoph , Tan Daniel S.W. , Peters Brock A. , Lincoln Stephen E. , Ballinger Dennis G. , Laramie Jason M. , Nilsen Geoffrey B. , Barber Thomas D. , Tan Patrick , Hillmer Axel M. , Ng Pauline C.
Published: March 2023

Validation of mutation signatures based on somatic variants, identified via RNA sequencing, among 83 Korean lung adenocarcinoma patients (47 smokers and 36 never-smokers) in another study [28].
Supplementary Figure 6 from Potassium Channel KCNA1 Modulates Oncogene-Induced Senescence and Transformation
Authors: Lallet-Daher Hélène , Wiel Clotilde , Gitenay Delphine , Navaratnam Naveenan , Augert Arnaud , Le Calvé Benjamin , Verbeke Stéphanie , Carling David , Aubert Sébastien , Vindrieux David , Bernard David
Published: March 2023

PDF - 83KB, PKA activation favors escape from OIS hallmarks.
Supplementary Figure 3 from Potassium Channel KCNA1 Modulates Oncogene-Induced Senescence and Transformation
Authors: Lallet-Daher Hélène , Wiel Clotilde , Gitenay Delphine , Navaratnam Naveenan , Augert Arnaud , Le Calvé Benjamin , Verbeke Stéphanie , Carling David , Aubert Sébastien , Vindrieux David , Bernard David
Published: March 2023

PDF - 151KB, KCNA1 knockdown and KCNA1 mutant S446E promote OIS escape.
Supplementary Figure 6 from NDY1/KDM2B Functions as a Master Regulator of Polycomb Complexes and Controls Self-Renewal of Breast Cancer Stem Cells
Authors: Kottakis Filippos , Foltopoulou Parthena , Sanidas Ioannis , Keller Patricia , Wronski Ania , Dake Benjamin T. , Ezell Scott A. , Shen Zhu , Naber Stephen P. , Hinds Philip W. , McNiel Elizabeth , Kuperwasser Charlotte , Tsichlis Philip N.
Published: March 2023

PDF file - 59KB, The knockdown of NDY1/KDM2B suppresses the activity of the Wnt pathway, despite the upregulation of Wnt1.
Supplementary Figure S2 from HMGB1 Enhances Immune Suppression by Facilitating the Differentiation and Suppressive Activity of Myeloid-Derived Suppressor Cells
Authors: Parker Katherine H. , Sinha Pratima , Horn Lucas A. , Clements Virginia K. , Yang Huan , Li Jianhua , Tracey Kevin J. , Ostrand-Rosenberg Suzanne
Published: March 2023

Supplementary Figure S2. Treatment with ethyl pyruvate does not alter arginase or iNOS expression or induce MDSC apoptosis as compared to control-treated MDSC.
Supplementary Methods from HIC1 Silencing in Triple-Negative Breast Cancer Drives Progression through Misregulation of LCN2
Authors: Cheng Guangcun , Sun Xueqing , Wang Jinglong , Xiao Gang , Wang Xiumin , Fan Xuemei , Zu Lidong , Hao Mingang , Qu Qing , Mao Yan , Xue Yunjing , Wang Jianhua
Published: March 2023

PDF file - 228K
Supplementary Figure 8 from HIC1 Silencing in Triple-Negative Breast Cancer Drives Progression through Misregulation of LCN2
Authors: Cheng Guangcun , Sun Xueqing , Wang Jinglong , Xiao Gang , Wang Xiumin , Fan Xuemei , Zu Lidong , Hao Mingang , Qu Qing , Mao Yan , Xue Yunjing , Wang Jianhua
Published: March 2023

PDF file - 344K, Endogenous HIC1 knockdown promotes cell migration and invasion in MCF-10A cells.
Video S1 from The NADH Oxidase ENOX1, a Critical Mediator of Endothelial Cell Radiosensitization, Is Crucial for Vascular Development
Authors: Venkateswaran Amudhan , Sekhar Konjeti R. , Levic Daniel S. , Melville David B. , Clark Travis A. , Rybski Witold M. , Walsh Alexandra J. , Skala Melissa C. , Crooks Peter A. , Knapik Ela W. , Freeman Michael L.
Published: March 2023

Video S1 MOV file 4944K, circulation in control morphant
Supplementary Table 2 from Acquired Expression of NFATc1 Downregulates E-Cadherin and Promotes Cancer Cell Invasion
Authors: Oikawa Tsukasa , Nakamura Atsuko , Onishi Nobuyuki , Yamada Taketo , Matsuo Koichi , Saya Hideyuki
Published: March 2023

XLS file, 30K, List of a primer pair used for ChIP assay.
DataSet S1 from The NADH Oxidase ENOX1, a Critical Mediator of Endothelial Cell Radiosensitization, Is Crucial for Vascular Development
Authors: Venkateswaran Amudhan , Sekhar Konjeti R. , Levic Daniel S. , Melville David B. , Clark Travis A. , Rybski Witold M. , Walsh Alexandra J. , Skala Melissa C. , Crooks Peter A. , Knapik Ela W. , Freeman Michael L.
Published: March 2023

XLSX file 150K, Genes that exhibit a 2 fold or greater change in expression - P less than 0.05
Data Supplement from Osteopontin Shapes Immunosuppression in the Metastatic Niche
Authors: Sangaletti Sabina , Tripodo Claudio , Sandri Sara , Torselli Ilaria , Vitali Caterina , Ratti Chiara , Botti Laura , Burocchi Alessia , Porcasi Rossana , Tomirotti Andrea , Colombo Mario P. , Chiodoni Claudia
Published: March 2023

Supplemental Figure 3. Immunostaining for STAT3 phosphorylation in lungs from WT and Spp1-/- tumor bearing mice.
Supplementary Figure 4 from RAE1 Ligands for the NKG2D Receptor Are Regulated by STING-Dependent DNA Sensor Pathways in Lymphoma
Authors: Lam Adeline R. , Le Bert Nina , Ho Samantha S.W. , Shen Yu J. , Tang Melissa L.F. , Xiong Gordon M. , Croxford J. Ludovic , Koo Christine X. , Ishii Ken J. , Akira Shizuo , Raulet David H. , Gasser Stephan
Published: March 2023

PDF file - 400K, Specificity control of cytosolic DNA stainings.
Supplementary Figure 2 from RAE1 Ligands for the NKG2D Receptor Are Regulated by STING-Dependent DNA Sensor Pathways in Lymphoma
Authors: Lam Adeline R. , Le Bert Nina , Ho Samantha S.W. , Shen Yu J. , Tang Melissa L.F. , Xiong Gordon M. , Croxford J. Ludovic , Koo Christine X. , Ishii Ken J. , Akira Shizuo , Raulet David H. , Gasser Stephan
Published: March 2023

PDF file - 155K, Phosphorylation of TBK1S172 in response to DNA damage.
Supplementary Figure 3 from CRR9/CLPTM1L Regulates Cell Survival Signaling and Is Required for Ras Transformation and Lung Tumorigenesis
Authors: James Michael A. , Vikis Haris G. , Tate Everett , Rymaszewski Amy L. , You Ming
Published: March 2023

PDF file - 219K, eQTL for CLPTM1L in adipose collected from 856 healthy female twins of the MuTHER resource.
Supplementary Figure 2 from CRR9/CLPTM1L Regulates Cell Survival Signaling and Is Required for Ras Transformation and Lung Tumorigenesis
Authors: James Michael A. , Vikis Haris G. , Tate Everett , Rymaszewski Amy L. , You Ming
Published: March 2023

PDF file - 82K, Waterfall plot of relative CLPTM1L expression.
Supplementary Materials and Methods, Figure Legends from Curative Properties of Noninternalizing Antibody–Drug Conjugates Based on Maytansinoids
Authors: Perrino Elena , Steiner Martina , Krall Nikolaus , Bernardes Gonçalo J.L. , Pretto Francesca , Casi Giulio , Neri Dario
Published: March 2023

PDF file - 162KB
Supplementary Tables 1 - 2 from A Systems Biology Approach Identifies Effective Tumor–Stroma Common Targets for Oral Squamous Cell Carcinoma
Authors: Meng Wenxia , Wu Yun , He Xin , Liu Chuanxia , Gao Qinghong , Ge Lin , Wu Lanyan , Liu Ying , Guo Yiqing , Li Xiaoyu , Liu Yurong , Chen Sixiu , Kong Xiangli , Liang Zhi , Zhou Hongmei
Published: March 2023

PDF file - 102K, Immunostaining of SPP1 in the 127 OSCC tissues in TG2: correlation with clinicopathological parameters (S1); Functional annotation of SPP1Net (S2).
Supplementary Figure 1 from Universal Marker and Detection Tool for Human Sarcoma Circulating Tumor Cells
Authors: Satelli Arun , Mitra Abhisek , Cutrera Jeffry J. , Devarie Marcos , Xia Xueqing , Ingram Davis R. , Dibra Denada , Somaiah Neeta , Torres Keila E. , Ravi Vinod , Ludwig Joseph A. , Kleinerman Eugenie S. , Li Shulin
Published: March 2023

PDF file - 3630KB, Detection of cell surface vimentin using western blotting, flow cytometry. Determination of specificity and sensitivity of 84-1 antibody.
Supplementary Figure Legends from YAP-Induced Resistance of Cancer Cells to Antitubulin Drugs Is Modulated by a Hippo-Independent Pathway
Authors: Zhao Yulei , Khanal Prem , Savage Paul , She Yi-Min , Cyr Terry D. , Yang Xiaolong
Published: March 2023

PDF file - 69KB
Supplementary Figure Legends from Androgen Receptor Splice Variants Determine Taxane Sensitivity in Prostate Cancer
Authors: Thadani-Mulero Maria , Portella Luigi , Sun Shihua , Sung Matthew , Matov Alexandre , Vessella Robert L. , Corey Eva , Nanus David M. , Plymate Stephen R. , Giannakakou Paraskevi
Published: March 2023

PDF file - 50KB
Supplementary Figure 2 from Androgen Receptor Splice Variants Determine Taxane Sensitivity in Prostate Cancer
Authors: Thadani-Mulero Maria , Portella Luigi , Sun Shihua , Sung Matthew , Matov Alexandre , Vessella Robert L. , Corey Eva , Nanus David M. , Plymate Stephen R. , Giannakakou Paraskevi
Published: March 2023

PDF file - 152KB, Antibody detection of AR in M12 series.
Supplementary Figure 1 from Androgen Receptor Splice Variants Determine Taxane Sensitivity in Prostate Cancer
Authors: Thadani-Mulero Maria , Portella Luigi , Sun Shihua , Sung Matthew , Matov Alexandre , Vessella Robert L. , Corey Eva , Nanus David M. , Plymate Stephen R. , Giannakakou Paraskevi
Published: March 2023

PDF file - 112KB, Microtubule co-sedimentation assay in a different cell line confirms that the C-ter of AR mediates association with microtubules.
Supplementary Figure Legend from Adenosine-to-Inosine RNA Editing Mediated by ADARs in Esophageal Squamous Cell Carcinoma
Authors: Qin Yan-Ru , Qiao Jun-Jing , Chan Tim Hon Man , Zhu Ying-Hui , Li Fang-Fang , Liu Haibo , Fei Jing , Li Yan , Guan Xin-Yuan , Chen Leilei
Published: March 2023

PDF file - 145K
Supplementary Table 1 from A Mechanism of Hypoxia-Mediated Escape from Adaptive Immunity in Cancer Cells
Authors: Barsoum Ivraym B. , Smallwood Chelsea A. , Siemens D. Robert , Graham Charles H.
Published: March 2023

PDF file - 106K, Supplementary Table 1: Statistical analysis (two-way ANOVA) of results of cytolytic assays.
Supplementary Figures 1 - 4 from A Mechanism of Hypoxia-Mediated Escape from Adaptive Immunity in Cancer Cells
Authors: Barsoum Ivraym B. , Smallwood Chelsea A. , Siemens D. Robert , Graham Charles H.
Published: March 2023

PDF file - 432K, Supplementary figures 1-2: HIF-1alpha-dependent up-regulation of PD-L1 expression in various tumour cell lines and co-localization of HIF-1alpha and PD-L1 in subcutaneous 4T1 tumours. Supplementary figure 3: Non-specific cytolytic activity of mouse CTLs against B16-F10 cells and total cytolytic activity (specific and non-specific) of mouse CTLs against B16-OVA cells. Supplementary figure 4: Effect of hypoxia and transfection with PD-L1 siRNA on PD-L1 protein levels in B16-OVA cells as well as effect of nitroglycerin therapy on the orthotopic growth of 4T1 tumours.
Supplementary Figure 3 from Adenosine-to-Inosine RNA Editing Mediated by ADARs in Esophageal Squamous Cell Carcinoma
Authors: Qin Yan-Ru , Qiao Jun-Jing , Chan Tim Hon Man , Zhu Ying-Hui , Li Fang-Fang , Liu Haibo , Fei Jing , Li Yan , Guan Xin-Yuan , Chen Leilei
Published: March 2023

PDF file - 759K, The total mRNA levels of AZIN1 (left panel) and FLNB (right panel) in 69 matched pairs of ESCC and NT specimens in Cohort 1 (Paired Student's t test).
Supplemental Figure Legends from Adenosine-to-Inosine RNA Editing Mediated by ADARs in Esophageal Squamous Cell Carcinoma
Authors: Qin Yan-Ru , Qiao Jun-Jing , Chan Tim Hon Man , Zhu Ying-Hui , Li Fang-Fang , Liu Haibo , Fei Jing , Li Yan , Guan Xin-Yuan , Chen Leilei
Published: March 2023

Legend for Supplemental Figures S1-S4
Supplementary Figure 9 from β-Catenin Inhibitor ICAT Modulates the Invasive Motility of Melanoma Cells
Authors: Domingues Mélanie J. , Rambow Florian , Job Bastien , Papon Laura , Liu Wanguo , Larue Lionel , Bonaventure Jacky
Published: March 2023

PDF file - 218K, Un-cropped immunoblot images. Original images used to generate panels in Figures 6, 7, S3 and S5.
SSupplementary Tables 1 - 2 from Adenosine-to-Inosine RNA Editing Mediated by ADARs in Esophageal Squamous Cell Carcinoma
Authors: Qin Yan-Ru , Qiao Jun-Jing , Chan Tim Hon Man , Zhu Ying-Hui , Li Fang-Fang , Liu Haibo , Fei Jing , Li Yan , Guan Xin-Yuan , Chen Leilei
Published: March 2023

PDF file - 75K, IHC scores of ADAR1 in 136 matched pairs of primary ESCCs and (NT) tissues (S1); The positive correlation between the tumoral overexpression of ADAR1 and tumoral genomic amplification of ADAR1 (S2).
Supplementary Figure Legends from Activation of the Glutamate Receptor GRM1 Enhances Angiogenic Signaling to Drive Melanoma Progression
Authors: Wen Yu , Li Jiadong , Koo Jasmine , Shin Seung-Shick , Lin Yong , Jeong Byeong-Seon , Mehnert Janice M. , Chen Suzie , Cohen-Sola Karine A. , Goydos James S.
Published: March 2023

PDF file - 42KB
Supplementary Figure 4 from β-Catenin Inhibitor ICAT Modulates the Invasive Motility of Melanoma Cells
Authors: Domingues Mélanie J. , Rambow Florian , Job Bastien , Papon Laura , Liu Wanguo , Larue Lionel , Bonaventure Jacky
Published: March 2023

PDF file - 234K, Stable exogenous ICAT expression increases Lu1205 and Mel501 cell lines migration.
Supplementary Figure 1 from β-Catenin Inhibitor ICAT Modulates the Invasive Motility of Melanoma Cells
Authors: Domingues Mélanie J. , Rambow Florian , Job Bastien , Papon Laura , Liu Wanguo , Larue Lionel , Bonaventure Jacky
Published: March 2023

PDF file - 129K, IF staining of ICAT and b-catenin in melanoma cells.
Data Supplement from Heparanase Cooperates with Ras to Drive Breast and Skin Tumorigenesis
Authors: Boyango Ilanit , Barash Uri , Naroditsky Inna , Li Jin-Ping , Hammond Edward , Ilan Neta , Vlodavsky Israel
Published: March 2023

Supplementary Figure Legends
Data Supplement from Heparanase Cooperates with Ras to Drive Breast and Skin Tumorigenesis
Authors: Boyango Ilanit , Barash Uri , Naroditsky Inna , Li Jin-Ping , Hammond Edward , Ilan Neta , Vlodavsky Israel
Published: March 2023

Supplementary Figure 2: Over-expression of heparanase/8C in MCF10AT1 cells.
Data Supplement from Heparanase Cooperates with Ras to Drive Breast and Skin Tumorigenesis
Authors: Boyango Ilanit , Barash Uri , Naroditsky Inna , Li Jin-Ping , Hammond Edward , Ilan Neta , Vlodavsky Israel
Published: March 2023

Supplementary Figure 5: Histological evaluation.
Data Supplement from Heparanase Cooperates with Ras to Drive Breast and Skin Tumorigenesis
Authors: Boyango Ilanit , Barash Uri , Naroditsky Inna , Li Jin-Ping , Hammond Edward , Ilan Neta , Vlodavsky Israel
Published: March 2023

Supplementary Figure 6: Decreased tumor development by Hpa-Tg mice treated with PG545, a heparanase inhibitor.
Supplementary FIgure S6 from ASC-J9 Suppresses Renal Cell Carcinoma Progression by Targeting an Androgen Receptor–Dependent HIF2α/VEGF Signaling Pathway
Authors: He Dalin , Li Lei , Zhu Guodong , Liang Liang , Guan Zhenfeng , Chang Luke , Chen Yuan , Yeh Shuyuan , Chang Chawnshang
Published: March 2023

Figure. S6. VHL inhibit HIF-2a and VEGF expression independent AR.
Supplementary FIgure S3 from ASC-J9 Suppresses Renal Cell Carcinoma Progression by Targeting an Androgen Receptor–Dependent HIF2α/VEGF Signaling Pathway
Authors: He Dalin , Li Lei , Zhu Guodong , Liang Liang , Guan Zhenfeng , Chang Luke , Chen Yuan , Yeh Shuyuan , Chang Chawnshang
Published: March 2023

Figure. S3. RCC cell proliferative ability were determined by BrdU incorporation assay.
Supplementary Table 4 from CD44v8-10 Is a Cancer-Specific Marker for Gastric Cancer Stem Cells
Authors: Lau Wen Min , Teng Eileen , Chong Hui Shan , Lopez Kirsten Anne Pagaduan , Tay Amy Yuh Ling , Salto-Tellez Manuel , Shabbir Asim , So Jimmy Bok Yan , Chan Shing Leng
Published: March 2023

PDF file - 20KB, Supplementary Table S4 shows p53 mutation status and proportion of CD44+ cells in gastric tumor xenografts.
Supplementary Table 3 from CD44v8-10 Is a Cancer-Specific Marker for Gastric Cancer Stem Cells
Authors: Lau Wen Min , Teng Eileen , Chong Hui Shan , Lopez Kirsten Anne Pagaduan , Tay Amy Yuh Ling , Salto-Tellez Manuel , Shabbir Asim , So Jimmy Bok Yan , Chan Shing Leng
Published: March 2023

PDF file - 24KB, Supplementary Table S3 shows effects of CD44 variant over-expression and knockdown on tumor initiation potential.
Supplementary Figure Legend from NUAK2 Amplification Coupled with PTEN Deficiency Promotes Melanoma Development via CDK Activation
Authors: Namiki Takeshi , Yaguchi Tomonori , Nakamura Kenta , Valencia Julio C. , Coelho Sergio G. , Yin Lanlan , Kawaguchi Masakazu , Vieira Wilfred D. , Kaneko Yasuhiko , Tanemura Atsushi , Katayama Ichiro , Yokozeki Hiroo , Kawakami Yutaka , Hearing Vincent J.
Published: March 2023

Supplementary Figure Legend
Supplementary Figure Legends from CD44v8-10 Is a Cancer-Specific Marker for Gastric Cancer Stem Cells
Authors: Lau Wen Min , Teng Eileen , Chong Hui Shan , Lopez Kirsten Anne Pagaduan , Tay Amy Yuh Ling , Salto-Tellez Manuel , Shabbir Asim , So Jimmy Bok Yan , Chan Shing Leng
Published: March 2023

PDF file - 33KB
Supplementary Figure 4 from CD44v8-10 Is a Cancer-Specific Marker for Gastric Cancer Stem Cells
Authors: Lau Wen Min , Teng Eileen , Chong Hui Shan , Lopez Kirsten Anne Pagaduan , Tay Amy Yuh Ling , Salto-Tellez Manuel , Shabbir Asim , So Jimmy Bok Yan , Chan Shing Leng
Published: March 2023

PDF file - 93KB, Supplementary Figure S4 shows gating strategy for sorting of CD44 depleted TMK1 cells for tumor initiation assay and xenograft tumors formed.
Supplementary Data 4 from Circadian Regulation of mTOR by the Ubiquitin Pathway in Renal Cell Carcinoma
Authors: Okazaki Hiroyuki , Matsunaga Naoya , Fujioka Takashi , Okazaki Fumiyasu , Akagawa Yui , Tsurudome Yuuya , Ono Mayumi , Kuwano Michihiko , Koyanagi Satoru , Ohdo Shigehiro
Published: March 2023

PDF file - 188K, Temporal expression profiles of mTOR and Fbxw7 in BALB/c mice livers.
Supplementary Data 3 from Circadian Regulation of mTOR by the Ubiquitin Pathway in Renal Cell Carcinoma
Authors: Okazaki Hiroyuki , Matsunaga Naoya , Fujioka Takashi , Okazaki Fumiyasu , Akagawa Yui , Tsurudome Yuuya , Ono Mayumi , Kuwano Michihiko , Koyanagi Satoru , Ohdo Shigehiro
Published: March 2023

PDF file - 117K, Schematic representation of the mouse Fbxw7 promoter.
Supplementary Data 1 from Circadian Regulation of mTOR by the Ubiquitin Pathway in Renal Cell Carcinoma
Authors: Okazaki Hiroyuki , Matsunaga Naoya , Fujioka Takashi , Okazaki Fumiyasu , Akagawa Yui , Tsurudome Yuuya , Ono Mayumi , Kuwano Michihiko , Koyanagi Satoru , Ohdo Shigehiro
Published: March 2023

PDF file - 56K, Comparison of mTOR activity between normal footpads and RenCa tumor tissue.
Supplementary Figure 9 from IL-17A Produced by γδ T Cells Promotes Tumor Growth in Hepatocellular Carcinoma
Authors: Ma Shoubao , Cheng Qiao , Cai Yifeng , Gong Huanle , Wu Yan , Yu Xiao , Shi Liyun , Wu Depei , Dong Chen , Liu Haiyan
Published: March 2023

PDF file - 133KB, Proposed mechanism by which IL-17A suppresses anti-tumor immune responses and promotes tumor growth in HCC.
Supplementary Table 8 from Proteogenomic Analysis Reveals Unanticipated Adaptations of Colorectal Tumor Cells to Deficiencies in DNA Mismatch Repair
Authors: Halvey Patrick J. , Wang Xiaojing , Wang Jing , Bhat Ajaz A. , Dhawan Punita , Li Ming , Zhang Bing , Liebler Daniel C. , Slebos Robbert J.C.
Published: March 2023

PDF file - 1496K, RKO versus other cell lines.
Supplementary Table 3 from Proteogenomic Analysis Reveals Unanticipated Adaptations of Colorectal Tumor Cells to Deficiencies in DNA Mismatch Repair
Authors: Halvey Patrick J. , Wang Xiaojing , Wang Jing , Bhat Ajaz A. , Dhawan Punita , Li Ming , Zhang Bing , Liebler Daniel C. , Slebos Robbert J.C.
Published: March 2023

PDF file - 857K, Standard search spectral table.
Supplementary Figures 1 - 7 from Targeting PARP-1 Allosteric Regulation Offers Therapeutic Potential against Cancer
Authors: Steffen Jamin D. , Tholey Renee M. , Langelier Marie-France , Planck Jamie L. , Schiewer Matthew J. , Lal Shruti , Bildzukewicz Nikolai A. , Yeo Charles J. , Knudsen Karen E. , Brody Jonathan R. , Pascal John M.
Published: March 2023

PDF file - 318K, Figure S1. DNA binding affinity of full-length PARP-1 and various domain combinations. Figure S2. DNA binding affinities of deltaZn2 PARP-1 variants. Figure S3. Cell viability dose response curves of MIA PaCa-2 cells treated with non-platinum based agents. Figure S4. DNA binding affinities for mutants of 1-366deltaZn2. Figure S5. Confirmation of genomic incorporation of the plasmids. Figure S6. Western blot analysis for PARP-1 in the AR reporter assay. Figure S7. Validation of protein concentration by SDS-PAGE gel analysis.
Supplementary Table 2 from A Sequence Polymorphism in miR-608 Predicts Recurrence after Radiotherapy for Nasopharyngeal Carcinoma
Authors: Zheng Jian , Deng Jieqiong , Xiao Mang , Yang Lei , Zhang Liyuan , You Yonghe , Hu Min , Li Na , Wu Hongchun , Li Wei , Lu Jiachun , Zhou Yifeng
Published: March 2023

PDF file - 79K, Sequence of primers using real time RT-PCR analysis.
Supplementary Figure 2 from A Sequence Polymorphism in miR-608 Predicts Recurrence after Radiotherapy for Nasopharyngeal Carcinoma
Authors: Zheng Jian , Deng Jieqiong , Xiao Mang , Yang Lei , Zhang Liyuan , You Yonghe , Hu Min , Li Na , Wu Hongchun , Li Wei , Lu Jiachun , Zhou Yifeng
Published: March 2023

PDF file - 1764K, Kaplan-Meier OS curves of patients with NPC receiving radiotherapy by genotypes of miRNA-608 rs4919510C>G.
Supplementary Methods, Figure Legend, Tables 1 - 5 from Overexpression of the Transcription Factor MEF2D in Hepatocellular Carcinoma Sustains Malignant Character by Suppressing G2–M Transition Genes
Authors: Ma Leina , Liu Jia , Liu Limei , Duan Guangjie , Wang Qingliang , Xu Yanmin , Xia Feng , Shan Juanjuan , Shen Junjie , Yang Zhi , Bie Ping , Cui Youhong , Bian Xiu-Wu , Prieto Jesus , Avila Matías A. , Qian Cheng
Published: March 2023

PDF file - 229K, Supplementary Table S1. Correlation of clinical features of the HCC patients and MEF2D expression analyzed by immunohistochemistry Supplementary Table S2. Correlation of pathological features of the HCC patients and MEF2Dexpression analyzed by immunohistochemistry Supplementary Table S3. Information of predicted MEF2 binding sites in the promoters of RPRM, CDKN1A, GADD45Aand GADD45B Supplementary Table S4. Lentiviruses and adenoviruses used in this study Supplementary Table S5. Sequences of primers used for qRT-PCR
Supplementary Methods from Novel Mechanistic Insights into Ectodomain Shedding of EGFR Ligands Amphiregulin and TGF-α: Impact on Gastrointestinal Cancers Driven by Secondary Bile Acids
Authors: Nagathihalli Nagaraj S. , Beesetty Yugandhar , Lee Wooin , Washington M. Kay , Chen Xi , Lockhart A. Craig , Merchant Nipun B.
Published: March 2023

PDF file - 107KB
Supplementary Figure 4 from Overexpression of the Transcription Factor MEF2D in Hepatocellular Carcinoma Sustains Malignant Character by Suppressing G2–M Transition Genes
Authors: Ma Leina , Liu Jia , Liu Limei , Duan Guangjie , Wang Qingliang , Xu Yanmin , Xia Feng , Shan Juanjuan , Shen Junjie , Yang Zhi , Bie Ping , Cui Youhong , Bian Xiu-Wu , Prieto Jesus , Avila Matías A. , Qian Cheng
Published: March 2023

PDF file - 102K, Supplementary Figures S4: A series of constructs containing that luciferase expression was driven by promoters of RPRM, CDKN1A,GADD45A andGADD45B.
Supplementary Figure 3 from Overexpression of the Transcription Factor MEF2D in Hepatocellular Carcinoma Sustains Malignant Character by Suppressing G2–M Transition Genes
Authors: Ma Leina , Liu Jia , Liu Limei , Duan Guangjie , Wang Qingliang , Xu Yanmin , Xia Feng , Shan Juanjuan , Shen Junjie , Yang Zhi , Bie Ping , Cui Youhong , Bian Xiu-Wu , Prieto Jesus , Avila Matías A. , Qian Cheng
Published: March 2023

PDF file - 150K, Supplementary Figures S3: The enriched biological processes or molecular pathways presented by genes significantly affected by MEF2D downregulation in Huh7 cells.
Supplementary Figure 7 from Novel Mechanistic Insights into Ectodomain Shedding of EGFR Ligands Amphiregulin and TGF-α: Impact on Gastrointestinal Cancers Driven by Secondary Bile Acids
Authors: Nagathihalli Nagaraj S. , Beesetty Yugandhar , Lee Wooin , Washington M. Kay , Chen Xi , Lockhart A. Craig , Merchant Nipun B.
Published: March 2023

PDF file - 119KB, AREG inhibition decreases cell proliferation, migration and invasion in CRC and PDAC.
Supplementary Figure 6 from Novel Mechanistic Insights into Ectodomain Shedding of EGFR Ligands Amphiregulin and TGF-α: Impact on Gastrointestinal Cancers Driven by Secondary Bile Acids
Authors: Nagathihalli Nagaraj S. , Beesetty Yugandhar , Lee Wooin , Washington M. Kay , Chen Xi , Lockhart A. Craig , Merchant Nipun B.
Published: March 2023

PDF file - 68KB, DCA-mediated Src and EGFR-dependent cell cycle regulation.
Supplementary Figure S7 from 5-Lipoxygenase Is a Candidate Target for Therapeutic Management of Stem Cell–like Cells in Acute Myeloid Leukemia
Authors: Roos Jessica , Oancea Claudia , Heinssmann Maria , Khan Dilawar , Held Hannelore , Kahnt Astrid S. , Capelo Ricardo , la Buscató Estel , Proschak Ewgenij , Puccetti Elena , Steinhilber Dieter , Fleming Ingrid , Maier Thorsten J. , Ruthardt Martin
Published: March 2023

This figure depicts an additional IF analysis on NB4 cells showing the interactioin between b-catenin and 5-LO upon threatment with CJ13,610
Supplementary Figure S6 from 5-Lipoxygenase Is a Candidate Target for Therapeutic Management of Stem Cell–like Cells in Acute Myeloid Leukemia
Authors: Roos Jessica , Oancea Claudia , Heinssmann Maria , Khan Dilawar , Held Hannelore , Kahnt Astrid S. , Capelo Ricardo , la Buscató Estel , Proschak Ewgenij , Puccetti Elena , Steinhilber Dieter , Fleming Ingrid , Maier Thorsten J. , Ruthardt Martin
Published: March 2023

Laser scan confocal analysis of 5-LO and RARα protein localization in U937-PR9 cells.
Supplementary Figure 3 from Novel Mechanistic Insights into Ectodomain Shedding of EGFR Ligands Amphiregulin and TGF-α: Impact on Gastrointestinal Cancers Driven by Secondary Bile Acids
Authors: Nagathihalli Nagaraj S. , Beesetty Yugandhar , Lee Wooin , Washington M. Kay , Chen Xi , Lockhart A. Craig , Merchant Nipun B.
Published: March 2023

PDF file - 98KB, Src and EGFR are involved in the AREG and TGF-alpha dependent cell cycle regulation through EGFR signaling.
Supplementary Figure 1 from Novel Mechanistic Insights into Ectodomain Shedding of EGFR Ligands Amphiregulin and TGF-α: Impact on Gastrointestinal Cancers Driven by Secondary Bile Acids
Authors: Nagathihalli Nagaraj S. , Beesetty Yugandhar , Lee Wooin , Washington M. Kay , Chen Xi , Lockhart A. Craig , Merchant Nipun B.
Published: March 2023

PDF file - 92KB, AREG and TGF-alpha mRNA expression.
Supplementary Figures 1 - 5, Table 1 from COX-2 Drives Metastatic Breast Cells from Brain Lesions into the Cerebrospinal Fluid and Systemic Circulation
Authors: Allen Joshua E. , Patel Akshal S. , Prabhu Varun V. , Dicker David T. , Sheehan Jonas M. , Glantz Michael J. , El-Deiry Wafik S.
Published: March 2023

PDF file - 338KB, Figure S1. COX-2 is overexpressed in MDA-MB-231 cells. Figure S2. Celecoxib inhibits the invasion and migration capacity of breast cancer cells in vitro. Figure S3. Celecoxib inhibits the migration of breast cancer cells into the cerebrospinal fluid. Figure S4. Enumerating human breast cancer cells in mouse blood using the CellSearch system. Figure S5. Changes in CTC and CSFTC counts as a function of changes in neurological or systemic clinical symptoms of disease. Table S1. Receptor status of enrolled breast cancer patients.
Supplementary Table 1 from Cyclin E1 Deregulation Occurs Early in Secretory Cell Transformation to Promote Formation of Fallopian Tube–Derived High-Grade Serous Ovarian Cancers
Authors: Karst Alison M. , Jones Paul M. , Vena Natalie , Ligon Azra H. , Liu Joyce F. , Hirsch Michelle S. , Etemadmoghadam Dariush , Bowtell David D.L. , Drapkin Ronny
Published: March 2023

PDF file - 60K, Antibody conditions used for immunohistochemistry, Western blot, and immunofluorescent staining.
Supplementary Figure 7 from The CXCL7/CXCR1/2 Axis Is a Key Driver in the Growth of Clear Cell Renal Cell Carcinoma
Authors: Grépin Renaud , Guyot Mélanie , Giuliano Sandy , Boncompagni Marina , Ambrosetti Damien , Chamorey Emmanuel , Scoazec Jean-Yves , Negrier Sylvie , Simonnet Hélène , Pagès Gilles
Published: March 2023

PDF file - 42K, SB225002 increased IL-1B-dependent CXCL7 expression.
Supplementary Figure 6 from The CXCL7/CXCR1/2 Axis Is a Key Driver in the Growth of Clear Cell Renal Cell Carcinoma
Authors: Grépin Renaud , Guyot Mélanie , Giuliano Sandy , Boncompagni Marina , Ambrosetti Damien , Chamorey Emmanuel , Scoazec Jean-Yves , Negrier Sylvie , Simonnet Hélène , Pagès Gilles
Published: March 2023

PDF file - 387K, SB225002 decreased the number of blood vessels.
Supplementary Table 2 from Glioblastoma Cell Enrichment Is Critical for Analysis of Phosphorylated Drug Targets and Proteomic–Genomic Correlations
Authors: Mueller Claudius , deCarvalho Ana C. , Mikkelsen Tom , Lehman Norman L. , Calvert Valerie , Espina Virginia , Liotta Lance A. , Petricoin Emanuel F.
Published: March 2023

XLSX file - 17K, Antibody Information.
Supplementary Figure 4 from The CXCL7/CXCR1/2 Axis Is a Key Driver in the Growth of Clear Cell Renal Cell Carcinoma
Authors: Grépin Renaud , Guyot Mélanie , Giuliano Sandy , Boncompagni Marina , Ambrosetti Damien , Chamorey Emmanuel , Scoazec Jean-Yves , Negrier Sylvie , Simonnet Hélène , Pagès Gilles
Published: March 2023

PDF file - 268K, SB225002 inhibits proliferation and induces apoptosis of human microvascular endothelial cells (HMVEC).
Supplementary Table 1 from Glioblastoma Cell Enrichment Is Critical for Analysis of Phosphorylated Drug Targets and Proteomic–Genomic Correlations
Authors: Mueller Claudius , deCarvalho Ana C. , Mikkelsen Tom , Lehman Norman L. , Calvert Valerie , Espina Virginia , Liotta Lance A. , Petricoin Emanuel F.
Published: March 2023

XLSX file - 12K, Tumor Sample Information.
Supplementary Figure 2 from Glioblastoma Cell Enrichment Is Critical for Analysis of Phosphorylated Drug Targets and Proteomic–Genomic Correlations
Authors: Mueller Claudius , deCarvalho Ana C. , Mikkelsen Tom , Lehman Norman L. , Calvert Valerie , Espina Virginia , Liotta Lance A. , Petricoin Emanuel F.
Published: March 2023

PDF file - 129K, Schematic of potential protein sources and contribution to overall signal from tissue analysis.
Supplementary Figure 2 from The CXCL7/CXCR1/2 Axis Is a Key Driver in the Growth of Clear Cell Renal Cell Carcinoma
Authors: Grépin Renaud , Guyot Mélanie , Giuliano Sandy , Boncompagni Marina , Ambrosetti Damien , Chamorey Emmanuel , Scoazec Jean-Yves , Negrier Sylvie , Simonnet Hélène , Pagès Gilles
Published: March 2023

PDF file - 83K, Anti-CXCL7 antibodies have no effect on the blood vessel network.
Supplementary Figure 1 from The CXCL7/CXCR1/2 Axis Is a Key Driver in the Growth of Clear Cell Renal Cell Carcinoma
Authors: Grépin Renaud , Guyot Mélanie , Giuliano Sandy , Boncompagni Marina , Ambrosetti Damien , Chamorey Emmanuel , Scoazec Jean-Yves , Negrier Sylvie , Simonnet Hélène , Pagès Gilles
Published: March 2023

PDF file - 73K, CXCL7 antibodies inhibit tumor growth of two other independent models of ccRCC.
Supplementary Figure 1 from Slug Promotes Survival during Metastasis through Suppression of Puma-Mediated Apoptosis
Authors: Kim Seaho , Yao Jiahong , Suyama Kimita , Qian Xia , Qian Bin-Zhi , Bandyopadhyay Sanmay , Loudig Olivier , De Leon-Rodriguez Carlos , Zhou Zhen Ni , Segall Jeffrey , Macian Fernando , Norton Larry , Hazan Rachel B.
Published: March 2023

PDF file - 145KB, Supplementary Fig. S1. Slug does not affect EMT in PyMT-N-cad tumors.
Supplementary Figure Legends from Detection of Brain Tumor Cells in the Peripheral Blood by a Telomerase Promoter-Based Assay
Authors: MacArthur Kelly M. , Kao Gary D. , Chandrasekaran Sanjay , Alonso-Basanta Michelle , Chapman Christina , Lustig Robert A. , Wileyto E. Paul , Hahn Stephen M. , Dorsey Jay F.
Published: March 2023

PDF file - 73KB
Supplementary Figure 3 from PPARα Activation Can Help Prevent and Treat Non–Small Cell Lung Cancer
Authors: Skrypnyk Nataliya , Chen Xiwu , Hu Wen , Su Yan , Mont Stacey , Yang Shilin , Gangadhariah Mahesha , Wei Shouzuo , Falck John R. , Jat Jawahar Lal , Zent Roy , Capdevila Jorge H. , Pozzi Ambra
Published: March 2023

PDF file - 40K, Treatment of athymic mice orthotopically injected with human GFP-A549 cells with Bezafibrate.
Supplementary Figure 2 from PPARα Activation Can Help Prevent and Treat Non–Small Cell Lung Cancer
Authors: Skrypnyk Nataliya , Chen Xiwu , Hu Wen , Su Yan , Mont Stacey , Yang Shilin , Gangadhariah Mahesha , Wei Shouzuo , Falck John R. , Jat Jawahar Lal , Zent Roy , Capdevila Jorge H. , Pozzi Ambra
Published: March 2023

PDF file - 99K, Analysis of human GFP-A549 NSCLC tumor cells.
Supplementary Figure 4 from Detection of Brain Tumor Cells in the Peripheral Blood by a Telomerase Promoter-Based Assay
Authors: MacArthur Kelly M. , Kao Gary D. , Chandrasekaran Sanjay , Alonso-Basanta Michelle , Chapman Christina , Lustig Robert A. , Wileyto E. Paul , Hahn Stephen M. , Dorsey Jay F.
Published: March 2023

PDF file - 61KB, Supplementary Figure 4. Detection of EGFR-expressing CTCs from a patient with EGFR over-expressing high grade glioma.
Supplementary Materials and Methods, Figure Legends from miR-30-5p Functions as a Tumor Suppressor and Novel Therapeutic Tool by Targeting the Oncogenic Wnt/β-Catenin/BCL9 Pathway
Authors: Zhao Jian-Jun , Lin Jianhong , Zhu Di , Wang Xujun , Brooks Daniel , Chen Ming , Chu Zhang-Bo , Takada Kohichi , Ciccarelli Bryan , Admin Samir , Tao Jianguo , Tai Yu-Tzu , Treon Steven , Pinkus Geraldine , Kuo Winston Patrick , Hideshima Teru , Bouxsein Mary , Munshi Nikhil , Anderson Kenneth , Carrasco Ruben
Published: March 2023

PDF file - 141KB
Supplementary Figure 3 from miR-30-5p Functions as a Tumor Suppressor and Novel Therapeutic Tool by Targeting the Oncogenic Wnt/β-Catenin/BCL9 Pathway
Authors: Zhao Jian-Jun , Lin Jianhong , Zhu Di , Wang Xujun , Brooks Daniel , Chen Ming , Chu Zhang-Bo , Takada Kohichi , Ciccarelli Bryan , Admin Samir , Tao Jianguo , Tai Yu-Tzu , Treon Steven , Pinkus Geraldine , Kuo Winston Patrick , Hideshima Teru , Bouxsein Mary , Munshi Nikhil , Anderson Kenneth , Carrasco Ruben
Published: March 2023

PDF file - 1392KB, BMSCs decrease miR-30s levels, and enforced expression of miR-30s inhibits CAM-DR in MM cells.
Supplementary Figure 2 from miR-30-5p Functions as a Tumor Suppressor and Novel Therapeutic Tool by Targeting the Oncogenic Wnt/β-Catenin/BCL9 Pathway
Authors: Zhao Jian-Jun , Lin Jianhong , Zhu Di , Wang Xujun , Brooks Daniel , Chen Ming , Chu Zhang-Bo , Takada Kohichi , Ciccarelli Bryan , Admin Samir , Tao Jianguo , Tai Yu-Tzu , Treon Steven , Pinkus Geraldine , Kuo Winston Patrick , Hideshima Teru , Bouxsein Mary , Munshi Nikhil , Anderson Kenneth , Carrasco Ruben
Published: March 2023

PDF file - 1007KB, Knockdown expression of miR-30s enhances BCL9 expression in MM cells.
Supplementary Figures 1 - 6 from Collagen Signaling Enhances Tumor Progression after Anti-VEGF Therapy in a Murine Model of Pancreatic Ductal Adenocarcinoma
Authors: Aguilera Kristina Y. , Rivera Lee B. , Hur Hoon , Carbon Juliet G. , Toombs Jason E. , Goldstein Courtney D. , Dellinger Michael T. , Castrillon Diego H. , Brekken Rolf A.
Published: March 2023

PDF file - 2694K, Supplementary Figure 1: Characterization of tumor growth in KIC mice (LSL-KrasG12D; Cdkn2alox/lox; p48Cre). Supplementary Figure 2: Liver metastatic burden in KIC mice. Supplementary Figure 3: Level of hypoxia, collagen I, Hif1alpha, and Hexokinase II in tumors from mice treated with mcr84 or mcr84 plus Gem. Supplementary Figure 4: Anti-TGFbeta inhibits mcr84-induced collagen deposition. Supplementary Figure 5: PDA cells express collagen receptors and Sparc. Supplementary Figure 6: Peak1 activation by collagen is sensitive to Ddr1 blockade.
Data Supplement from High-Throughput Time-Resolved FRET Reveals Akt/PKB Activation as a Poor Prognostic Marker in Breast Cancer
Authors: Veeriah Selvaraju , Leboucher Pierre , de Naurois Julien , Jethwa Nirmal , Nye Emma , Bunting Tamara , Stone Richard , Stamp Gordon , Calleja Véronique , Jeffrey Stefanie S. , Parker Peter J. , Larijani Banafshé
Published: March 2023

Supplementary Figure 6: Distribution of Akt activation revealed by amplified FRET for all breast carcinoma patients (ER-/ER+).
Data Supplement from High-Throughput Time-Resolved FRET Reveals Akt/PKB Activation as a Poor Prognostic Marker in Breast Cancer
Authors: Veeriah Selvaraju , Leboucher Pierre , de Naurois Julien , Jethwa Nirmal , Nye Emma , Bunting Tamara , Stone Richard , Stamp Gordon , Calleja Véronique , Jeffrey Stefanie S. , Parker Peter J. , Larijani Banafshé
Published: March 2023

Supplementary Figure 7: Quantification of endogenous pAkt (pT308) in fixed FFPE human normal and tumor breast tissue using amplified FRET.
Supplementary Figures 1 - 4 from Transient Ablation of Regulatory T cells Improves Antitumor Immunity in Colitis-Associated Colon Cancer
Authors: Pastille Eva , Bardini Katrin , Fleissner Diana , Adamczyk Alexandra , Frede Annika , Wadwa Munisch , von Smolinski Dorthe , Kasper Stefan , Sparwasser Tim , Gruber Achim D. , Schuler Martin , Sakaguchi Shimon , Roers Axel , Müller Werner , Hansen Wiebke , Buer Jan , Westendorf Astrid M.
Published: March 2023

PDF file - 149K, Suppl. Figure 1. The induction of colitis-associated colon cancer alters the expression of GARP, CD103 and CTLA-4 on T cells and regulatory T cells. Suppl. Figure 2. Increased percentages of regulatory T cells in the peripheral blood of patients with colon cancer. Suppl. Figure 3. Impact of DT treatment on the distribution of Tregs and adaptive immunity in DEREG mice. Suppl. Figure 4. Impact of DT treatment on the distribution of Tregs in DEREG mice.