bluuebunny/crossref_metadata_2025 huggingface dataset:
Experience in Teaching Science in Virtual Environment
Authors: Tibola Leandro Rosniak , Herpich Fabrício , Silva Patricia Fernanda da , Tarouco Liane Margarida Rockenbach
Published: May 2019

Labs are needed in science education, and schools usually lack appropriate conditions to provide active learning activities with experience. In schools, the lack of labs for science education is usual. The new technologies of 3D virtual worlds allow the user, through immersive virtual worlds, or metaverses, to experience situations similar to those possible in a real environment. A solution to the lack of labs is the virtual labs, which consist of virtual representations that reproduce the environment of a real lab. These are applications based on simulations, offering computational representations of reality. The simulation of concrete and real situations gives the student the opportunity to experiment, actively participating in the learning process by performing experiments that would otherwise not be possible due to safety issues (possible damage to students or the environment) or economy (cost of components involved and derived from the creation and operation of the lab). These virtual labs can be implemented on personal computers that exist in schools or even in the student's home. Users can work in the virtual lab, through their avatars, using experiments provided there, as well as acting collaboratively.
Economic Feasibility Study for The Installation of a Cogeneration System in A Timber Industry of Lages-Sc
Authors: Vargas Scharles Roberto , Rocca Graciela Alessandra Dela , Branco Nathielle Waldrigues , Wolf José Adelir , Ferreira Fernanda Cristina Silva
Published: May 2019

This research thematic is the Economic Viability Study, in order to implement a cogeneration system, in a logging company, located in the Santa Catarina highland plateau region. Thus, reducing its production cost, since much of it is due electricity purchase. Data collection of both production, consumption and expenses with electricity purchase and billing were carried out together with the company. Descriptive method was used, with case study. For the economic analysis, both net present value (NPV), internal rate of return (IRR) and payback period were used. With this information and crossing the data, the economic viability for this project became evident, as it can be visualized throughout of this article.
Quality of Work Life in Higher Education Institutions
Authors: Krauze Boone Daniele , Pitwak Rossoni Estela , Simão Rogério , São Pedro Filho Flávio de , Piacentini Marcos Tadeu Simões , Piacentini Alexandre Leonardo Simões
Published: May 2019

The quality of work life, whether in the public or private institution, aims to promote well-being for employees, so that they can perform their activities satisfied and motivated, thus contributing to an excellent organizational performance. This study is a review of the literature on the quality of life at work, in which approaches and applications were sought from public servants, especially from Higher Education Institutions. For that, bibliographic research was carried out, with an exploratory and descriptive character, with a qualitative approach and deductive method. The collection of data in front of the compiled and localized scientific works focused on the identification of existing models, among which Walton was considered the most adequate and therefore, with higher utility for the future study of deepening in an application with public servants of Higher education institutions. This model includes a structured questionnaire with eight criteria: social relevance of work life, use of skills, working conditions, social integration in the organization, work, and total living space and constitutionalism, fair and adequate compensation and opportunity for growth. It is understood that new research applied in this sense, help the managers of the HEIs studied in the decision making aimed at promoting improvements to the Quality of Life at Work.
Intrepid Teacher Abroad
Authors: Cotner Teresa
Published: May 2019

This study describes development of teacher knowledge through a short term, early field experience, for preservice teachers who taught place-based art lessons in a community-center in Japan. Eight U.S. undergraduate, pre-credential students participated in this study. The author of this paper, a participant observer, collected and examined pre- and post-questionnaire responses, participant observation field notes, photographs, and one three-years-after reflection, through constant comparison, thematic analysis, and explanatory case study.  This study found no negative outcomes for preservice teachers. Findings from this study concur with a growing body of literature that explores how a short term, international, early field experience can foster the development of teacher knowledge, including pedagogy, subject matter, students and environmental context, and further suggest that short term, international, early field experiences teaching place-based art can foster professional achievement.
Knowledge of the population of the northern state of Espírito Santo and Northeast of the state of Minas Gerais on Herpes Viruses and Perspectives of Care of Dentistry
Authors: Souza Julianna Godoi de , Silva Wanessa Soares Luiz , Nunes Marcus Antonius Da Costa , Guisso Luana Frigulha , Abreu Juscélio Clemente de , Rezende Bruno Augusto de , Freitas Kenia Roberta Reuter de , Amorim Patrícia Brandão , Ricardo Eci Fernandes , Gomes Eugênio Maria , Silva Daniel Rodrigues
Published: May 2019

This study aimed to measure the level of knowledge of HZV in northern municipalities in the state of Espirito Santo and Northeast of Minas Gerais in order to analyze and compare the variables investigated on the herpes virus. Specifically aims to understand the perception of this population about the forms of contagion, activating factors of the virus and the mechanism of access to information. Therefore, we carried out a literature review and research linked to it through the study method of approach to the case. In selected areas, individuals from 10 cities in the North of the Holy Spirit and Northeast of Minas Gerais, participated answering structured questionnaire. The results showed that a significant percentage have little information or complete ignorance about the disease, modes of transmission and its consequences for health. Much of the sample is unaware of the importance of the dentist to provide information and to treat cold sores, in addition to a lack of health services have been observed to provide information about the disease, its clinical signs and prevention, through educational activities for the population and 19% of the population has herpes labialis. Thus, it is concluded that most educational measures should be carried out, understanding that the greater the knowledge, the lower the infection rates, leading individuals to prevent and to treat when detected the expression of pathogenic signals. in addition to a lack of health services have been observed to provide information about the disease, its clinical signs and prevention, through educational activities for the population and 19% of the population has herpes labialis. Thus, it is concluded that most educational measures should be carried out, understanding that the greater the knowledge, the lower the infection rates, leading individuals to prevent and to treat when detected the expression of pathogenic signals. in addition to a lack of health services have been observed to provide information about the disease, its clinical signs and prevention, through educational activities for the population and 19% of the population has herpes labialis. Thus, it is concluded that most educational measures should be carried out, understanding that the greater the knowledge, the lower the infection rates, leading individuals to prevent and to treat when detected the expression of pathogenic signals.
Investigation of The DGs Effect on The Coordination Between Protective Elements in Distribution Network
Authors: Reda Abdallah , Farahat M. , Abdelgawad Amal F. , Taha A.T.M
Published: May 2019

Addition of Distributed Generators (DGs) to the electric network have more advantages to the network. It improves the voltage profile and the power flow in the network. In the last decade, DGs is used in power system, especially the distribution system. Coordination study for protective devices must be performed on the distribution network with DGs to reach selectivity with minimum clearance time of fault. Due to DG insertion to the electric system, the short circuit level is changed and coordination between protective elements should be done. This paper presents a technique to avoid the miscoordination problem between protective devices due to the impact of DG units insertion without any additional costs. The proposed technique depend on activating and updating the setting of network relays to achieve correct coordination. Also, it doesn't need any additional costs or any additional equipement to be installed in the electric network. This paper make studies on a real radial system of power transformer with its feeders of a 66kV utility substation before and after adding DGs. ETAP software is used to simulate the network under study.
HOME-WORK MANAGEMENT AND SOCIAL BEHAVIOUR DEVELOPMENT
Authors: Ugwuzor Miebi
Published: May 2019

Persons who work for firms together with their family members make up the society in which corporate entities operate. The traditional African society enjoyed relative peace and tranquility as well as a relatively low crime rate. However, the current apparently perturbing exhibition of undesirable behaviours in the Nigerian society calls for intervention by responsible corporate citizens to look into the social and emotional malaise and retool their internal policies and programmes to counteract any external threat such a menace may pose. This paper is a workplace approach to mitigating contemporary socio-behavioural ills through the management of Home-role and Work- role balance of employees for the socio-behavioural wellbeing of the society. It is an attempt at triggering new capacities in firms towards rethinking their Corporate Social Responsibility stance by embarking on viable workplace grown solutions to societal challenges and for the country to have a renewed hope for socio-cultural regeneration.
COLLECTIVE INTELLIGENCE (CROWDSOURCING) ON THE INTERNET
Authors: Jannuzzi Celeste Aida , Falsarella Orandi Mina , Oliveira Larissa Moraes de
Published: May 2019

The present work proposes to investigate the practice of collective intelligence (crowdsourcing) on the Internet by scientific institutions that develop or not sustainable actions, in order to characterize their use of the virtual environment in the process of knowledge generation for their own benefit. This is an empirical analysis based on a survey of data on the Internet, aiming to identify websites whose hosting organizations adopt collective intelligence practices to achieve their objectives in the generation of knowledge, necessarily of a scientific nature and/or related to sustainable development. As a result, it was possible to identify the adoption of this practice by several organizations, in which their level of dependence on the virtual environment as well as the virtual environment’s contribution to the accomplishment of their projects are observed.
FORMAÇÃO CONTEXTUALIZADA E CRIATIVA DE PROFESSORES DE MATEMÁTICA EM UMA ATIVIDADE DIDÁTICA NA DISCIPLINA DE FÍSICA I
Authors: OLIVEIRA MARGARETH SANTORO BAPTISTA DE , NASCIMENTO MARIA DA GLÓRIA FERNANDES DO , JÚNIOR AMADEU ALBINO
Published: May 2019

A docência atual exige a excelência dos profissionais educadores. Isso requer uma formação na qual, tão importante quanto o que se ensina, é como se ensina. Sendo assim, a formação dos licenciandos é responsabilidade das diferentes disciplinas que integram o currículo de cada curso. O professor formador é responsável por organizar atividades nas quais sejam apresentadas tarefas com potencial para desenvolver habilidades docentes. Configura-se dessa forma, a proposição do presente trabalho que é descrever o desenvolvimento de uma atividade da disciplina Física I, na licenciatura de Matemática – a elaboração de um plano de aula diferenciada contextualizado pela Cinemática ou Dinâmica. A metodologia efetivou-se em perspectiva dialógica, compartilhada e reflexiva no intento de ampliar a capacidade produtiva, contextualizada e criativa dos futuros professores. O percurso foi desenvolvido em quatro etapas consecutivas: motivação, atividades teóricas com a modelagem, produção de um plano de aula e reflexão e reorganização dos planos. Ao final da reflexão e do replanejamento, foi perceptível que os futuros professores (a partir de suas explicitações) entenderam a necessidade de saberes que possibilitem novas formas de ensinar e aprender. Os saberes a ensinar de Matemática, por fornecerem ferramentas para descrever fenômenos; os de Física, por apresentar e discutirem situações; e, dialeticamente, nortearem a utilização de ferramentas matemáticas. É indubitável que a satisfação das demandas surgidas durante o processo não foi total. Isso, longe de ser visto de forma negativa, pode ser motivação para a concepção identitária dos futuros professores como agentes ativos de seu processo de formação e desenvolvimento.
İnsanlarda kene ile bulaşan hastalık etkenleri ve Türkiye’deki mevcut durumu
Authors: AYDIN Mehmet Fatih , COŞKUN Ayşe
Published: April 2019

Vektörler ve vektörler ile bulaşan hastalık etkenleri önemli problemlere
neden olurlar. Keneler memeli, kuş ve sürüngenler gibi pek çok canlının kanıyla
beslenen vektörlerdir. Keneler kan emmeleri esnasında 200 kadar virüs, bakteri,
riketsiya, spiroket, protozoon ve helmint türlerini nakledebilirler. Kenelerin
insanlara naklettiği başlıca hastalık etkenleri; Kırım-Kongo kanamalı ateşi
virusu, kene kaynaklı ensefalit virusu, Powassan ensefalit virusu, Kyasanur
orman hastalık virusu, Colorado kene ateşi virusu, Babesia spp., Borrelia
burgdorferi sensu lato, Francisella
tularensis, Anaplasma phagocytophilum, Ehrlichia
chaffeensis ve Rickettsia rickettsii’dir. İnsanlara kenelerle bulaşan mikrobiyal
hastalık etkenleri; oluşturduğu hastalık, vektör, epidemiyoloji, belirtiler,
tanı ve tedavi bakımından bu derlemede özetlenmiş ve Türkiye’deki mevcut durumu
sunulmuştur.
Body Mass Index, Blood Pressure and Serum Cortisol Level as Stress Index in Symptomatic HIV/AIDS Male Subjects on Antiretroviral Therapy Negative to Malaria Parasite in Nnewi, Anambra State, Nigeria
Authors: P Ezeugwunne I , C Ogbodo E , A Analike R , J Onuora I , N Obi-Ezeani C , C Ugwu M , K Amah U , O Okezie A , C Onyenkwe C , E Ahaneku J
Published: April 2019

Background: HIV infection is a risk factor for a variety of endocrine problems. Objectives: This study investigated the body mass index (BMI), Systolic blood pressure (SBP), Diastolic blood pressure (DBP) and serum cortisol level as stress factor/index symptomatic HIV/AIDS male subjects on ART who are negative to malaria parasite in Nnewi, Anambra State, Nigeria. Methods: A total of 274 adult male participants aged between 18 and 60 (42 ±13) years were randomly recruited at the Voluntary Counseling and Testing (VCT) Centre in Nnamdi Azikiwe University Teaching Hospital and grouped based on WHO criteria for staging HIV into symptomatic HIV (stage 11) infected male participants on ART (A: n=69), Symptomatic HIV subjects not on ART (B: n= 69), Asymptomatic HIV positive subjects (C: n= 68) and HIV seronegative subjects (D: n= 68). Blood samples were collected from the participants for the determination of HIV status by immunochromatography and HIV confirmation by Western Blot. Enzyme-Linked Immunosorbent Assay (ELISA) was used to assay for cortisol level. Results: The results showed a significantly increased BMI and decreased mean serum cortisol level in HIV/AIDS seropositive participants on ART than in those, not on ART (p<0.05). Also, the BMI and mean serum cortisol level were significantly decreased and increased respectively in  HIV/AIDS seropositive participants not on ART than in Asymptomatic HIV positive subjects and control respectively (p<0.05). However, the mean SBP and DBP did not differ significantly between the groups studied (p>0.05). Conclusion: This study revealed a decreased stress index in HIV/AIDS subjects on ART with hypercortisolism and lower BMI in symptomatic HIV participants, not on ART.

Keywords: HIV; AIDS; Malaria uninfected male subjects; Cortisol; Blood pressure; Antiretroviral therapy.
Prevalence of Musculoskeletal Disorders in Workers In An Industry in Ahmednagar District, Maharashtra.
Authors: Chordiya Sneha , Nikhade Nitin
Published: April 2019

Introduction: Musculoskeletal disorders are a major public health problem in industrialized and developing countries. The present study was aimed to find out the prevalence of acute and chronic WMSD’s in Industrial workers. Methodology: This cross-sectional observational study was carried out in 60 workers of the Adon Block department workers of the electrical & automation industry, Ahmednagar. Pre-structured occupational Performa was filled by asking questions in the worker’s local language. The Nordic pain Questionnaire was filled by asking the subjects to mark the sites of pain on body chart paper. The risk factors for work-related musculoskeletal problems were assessed by the working posture of workers and repetitive movements in industrial set up. The data collected were interpreted and analyzed. Results: In the present study, 60 workers were selected, of which a number of females were 39 (65%) while males were 21 (35%). The Neck (20.2%) followed by the shoulder (14.9%), elbow (14.4%) and knee (14.4%) were most commonly involved. There was a statistically significant variation in the number of workers involved according to the posture (sitting vs standing) and part of the MSK system involved. Conclusion: The WMSD’s are common in Adon block department workers. The involvement of neck, shoulder, lower back and arm was common in sitting position, while the involvement of upper back, elbow and knee were common in standing position. The disorders are commonly seen in workers irrespective of their duration of work and gender.

Keywords: Musculoskeletal disorders; Industry Workers; Nordic pain Questionnaire; Ahmednagar.
Evaluation of Effect of Melatonin on Hematological Parameters in Patients of Periodontitis
Authors: Marawar Anagha , Marawar Pramod , H Nandal D , Kunkulol Rahul , Narwane Sandeep
Published: April 2019

Introduction: Considering the immunity enhancing property of melatonin, a study on the evaluation of the effect of melatonin on the hematological parameters in patients suffering from Periodontitis.  Methods: This study was conducted in the Department of Periodontics, Rural Dental College, Loni. Patients of chronic Periodontitis, of age between 18 to 65 years of either gender ready to give informed consent to participate in the study were included. Postoperative patients, patients having night duties, drivers and those using heavy machinery, pregnant women, lactating mothers, patients with any clinically significant systemic disease and patients on any other drugs were excluded from the study. Patients were divided into two Groups. Group B received scaling and root planning (SRP) and melatonin 3 mg per day were compared to Group A which received SRP only. The Total Leukocyte count, Differential Leukocyte count and Erythrocyte sedimentation rate of each patient was studied at a baseline, 1st (30 days) visit, 2nd (60 days) visit and 3rd (90 days) visit. Results: Both the groups consisted of 80 subjects each. Group A consisted of 71.25% male and 28.75% female patients. There were 56.25% male and 43.75% female patients in Group B. With respect to visit 3, the TLC was statistically lower in Group B. The neutrophil count of Group B was significantly lower during visit 3 as compared to Group A. The lymphocyte count of Group B was significantly lower than that of Group A during the visit 1, and also significantly higher during visit 3 on comparison with Group A. There was no statistically significant difference in the groups with respect to eosinophil and basophil count. The Monocyte count of Group B was statistically lower when compared to that of Group A. There was no statistically significant difference between ESR of Group A & Group B.  Conclusions: It can be concluded that melatonin has a positive effect on TLC and differential count of patients of periodontitis, conferring a new facet to the management of periodontitis and an attempt to impede the disease progression.

Keywords: Melatonin; Hematological parameters; Periodontitis; Total Leukocyte count; Differential Leukocyte count; Erythrocyte sedimentation rate; Scaling and Root Planning.
Effectiveness of Surgical Management of Ankle Fractures in Attaining the Stability of Ankle
Authors: L Ramesh , L Kiran Kumar , M Rakesh Chandra
Published: April 2019

Introduction: Ankle injuries comprise a major group of lower limb trauma. Many of these injuries can be treated by manipulative reduction and conservative treatment and some of these yield satisfactory results, so present study was undertaken to know the effectiveness of surgical management of ankle fractures. Method: 42 surgically treated displaced fractures are included and studied in detail of age, sex, occupation, type of fracture, mode of injury, type of treatment, Clinical evidence of fracture union, Radiological evidence of fracture union, Relation of talus in the ankle mortise, Range of mobility of the ankle, Residual disability and pain, Ability to walk and time of return to duty and complications were noted. Result:  42 cases were surgically treated, most of the patients were operated on an emergency basis within 24 hours of injury. Based on the mechanism of injury Pronation- External Rotation (30.9%) and Based on Ao Classification Type B - B2 (53.3%) were the major type of fractures. In the majority of cases, Malleolar screws type of implants used.  In overall the final status of patients is good (ability to walk).  Conclusion: Displaced ankle fractures need accurate open reduction and internal fixation and postoperative immobilization for 6 weeks. This will suffice to get good results. Post-operative rigid immobilization and protected weight bearing for 12 weeks is minimal to achieve good union followed by physiotherapy to restore the maximum range of movements

Keywords: Ankle Fractures; Surgical management, Stability; Effectiveness.
ANALISE DA CADEIA DE VALOR DA SOJA NO ESTADO DO TOCANTINS
Authors: Alves Erisvaldo Oliveira , Oliveira Nilton Marques de
Published: April 2019

This paper aims to analyze the soybean value chain characteristics in the state of Tocantins, Brazil. The Economic Base Theory was the theoretical input, and the Global Value Chain was the methodology used. The main findings suggest that soybean is the main culture in the agribusiness of Tocantins and its production is for the global marketplace; there is no value aggregation. It was observed that a large share of public funding goes for the business agriculture, and these characteristics aren’t in accordance to the family-based agriculture standard. It is appropriate to add value to the product and to use the North-South Railway in a rational way, thus, providing competitiveness to the chain.
TURISMO, GESTÃO HOTELEIRA E O DESENVOLVIMENTO SOCIOECONÔMICO NOS PAÍSES EM DESENVOLVIMENTO: MUNICIPIO DE INHAMBANE, MOÇAMBIQUE
Authors: Alcobia Orlando Miguel Pestana
Published: April 2019

This article aims to analyze the hotel units’ operational practices in Inhambane, assesses their socio-economic impacts into the local community and proposes hotel operations qualitative measures to promote sustainable socio-economic development. Follow the Quivy and Campenhoudt methodological model for social sciences and has the hotel units and their workers as objects of study. Presents the following dimensions: hotel operations multiplier effect, the employability quality generated by them, their contribution to the welfare infrastructures and their environmental policies. Remarks that the implemented hotel development model is based on a neoliberal matrix, mostly in result of foreign or multinational investments, not guaranteeing a significant multiplier effect in the local economy, its job offer quality is often precarious, unable to have a significant contribution to the local "welfare" infrastructures improvement and sometimes producing undesirable environmental costs. Concludes that it is pressing to rethink the whole model of tourism development in Inhambane, retaining in its territory the economic benefits of the touristic activities and transforming the local community in its main beneficiary.
Performance Analysis of Three Phase Two Quadrant Controlled Converter for DC Load Applications
Authors: Siddharthan S. T. , Ayyappa O. R. Sai , Kumar K. Karthik
Published: April 2019

This paper provides the operation and analysis of three phase two quadrant controlled converter. In this paper, the converter is being checked with varying the duty cycle for two different loads R and RL. The Power factor, Total Harmonic Distortion (THD) and efficiency are better for very low duty cycle which is the same for RL load. This analysis estimates THD and power factor at various conditions. The FFT analysis is done to find the harmonic content present in the input current waveform. This analysis is done using MATLAB software.
Poor and Disliking Subjects in Relation to Residence - A Case Study on High School Students
Authors: Podila Sankara Pitchaiah , Sultana Nazia
Published: April 2019

Liking and Disliking towards a subject is a common feature among the high school students. Some students feel easy about some subjects and tough about some other. The response was taken from 2743 students, studying 8th to 10th classes (Rural: 869 and Urban: 1874) in Government High schools of Guntur District, Andhra Pradesh. The study found that High percent of rural students are Poor in almost all the subjects, except Natural Science compared to the urban students. In both cases, Telugu subject is easy for them. High percent of rural students disliking all the subjects compared to the urban.
PENGEMBANGAN MEDIA PEMBELAJARAN E-COMIC DALAM PEMBELAJARAN MATEMATIKA
Authors: Siregar Nuriza , Suherman Suherman , Masykur Rubhan , Ningtias Rahma Sari
Published: April 2019

This article intends to develop mathematics learning media in the form of e-Comic in mathematics teaching and learning. The method of this research was eight stages developing from Borg and Gall which has been modified by Sugiyono. Instrument of this research was validation questionnaire and feedback questionnaire for students. Technique of data analysis used descriptive quantitative and descriptive qualitative. To test the effectiveness, the researcher implied and used t test. The result shows that media of learning in the form of e-Comic mathematics on the arithmetic subject was eligible. It was obtained from validator. While, the effectiveness of media was obtained from the results of the post-test t-test of students with the results obtained 14.333 and  2.109 so that. It can be defined that the class which was taught by implementing and using e Comic media was better that the conventional class. In conclusion, the developed media can be used as a medium of learning mathematics and it is applicable in mathematics teaching and learning.   Artikel ini memiliki tujuan untuk mengembangkan media pembelajaran matematika berupa e-Comic dalam pembelajaran matematika. Metode penelitian yang digunakan adalah 8 tahap metode pengembangan dari borg and gall yang sudah dimodifikasi oleh Sugiyono. Instrument yang digunakan adalah angket validasi dan angket respon peserta didik. Teknik analisis data yang digunakan adalah deskriptif kuantitatif dan deskriptif kualitatif. Uji yang digunakan untuk melihat keefektifan media adalah uji t. hasil penelitian ini adalah sebuah media pembelajaan berupa e-Comicmatematika pada pokok bahasan aritmetik dengan kriteria kelayakan yang didapat dari validator sangat layak, kemenarikan yang didiapat dari peserta didik sangat menarik. Sedangakan keefektifan media didapatkan dari hasil uji t post-test peserta didik dengan hasil perhitungan diperoleh  dan  sehingga  dalam arti kelas yang medapat kemampuan pemecahan masalah  perlakuan pembelajaran media e-Comicmatematika lebih baik (efektif) dari pada kelas yang mendapat perlakuan metode ceramah (tidak menggunakan media pembelajaran). Berdasarkan semua ini dapat disimpulkan bahwa media yang dikembangkan dapat digunakan sebagai media pembelajaran matematika.
CONSIDERAÇÕES ACERCA DO PROCESSO DE CONSTITUIÇÃO DA NOÇÃO DE SUJEITO
Authors: Fernandes Pedro
Published: May 2019

O presente artigo aborda alguns aspectos teóricos do processo de constituição da noção de sujeito. Partindo de uma breve exposição da concepção mítica, avança pela busca do conhecimento de si, enfatizando as contribuições de Sócrates e Platão e, sobretudo, de Aristóteles, para quem o sujeito (hypokeimenon) é entendido como aquilo de que se fala ou ao que se atribuem qualidades ou determinações, ou aquilo ao qual inerem qualidades ou determinações, ou seja, uma espécie de substrato. Por fim, apresenta-se como a noção de sujeito, na longa tradição em que as traduções e interpretações foram se amalgamando, tornou-se ‘princípio da denominação do sujeito pela ação’ e, na modernidade, a substituição do sujeito de ação (agente) pelo sujeito do conhecimento.
Tuberculosis pulmonar en edad pediátrica
Authors: Lucín Yagual Teresa Anabel , Yuz Humanante Yadira Elizabeth , Villacreses Parrales Carlos David , Cáceres Manzano Veronica Paulina
Published: April 2019

La infección por Mycobacterium tuberculosis en menores de 15 años tiene un comportamiento epidemiológico y clínico diferente al del adulto. Se presenta el caso de tuberculosis infantil, menor de 13 años de edad masculino que ingresa a la unidad hospitalaria inestable con pronóstico reservado con cuadro de insuficiencia respiratoria y desnutrición proteico calórica, se realiza baciloscopia que resulta negativa, una segunda prueba GeneXpert que resulta positiva; permanece en UCI aislado por 44 días, recibió múltiples esquemas de antibiótico incluido el antifïmico, evoluciona desfavorablemente a las terapéuticas aplicadas, fallece de paro cardiorespiratorio. Tenía antecedentes familiares, madre tratada por 10 años de tuberculosis pulmonar, hermano del menor presento derrame pleural hace 9 años, sin diagnóstico de TB, la abuela materna con antecedentes de TB. Con lo presentado se evidencia la importancia de establecer las medidas necesarias para optimizar el diagnóstico precoz y adecuado de las distintas formas clínicas de tuberculosis en niños
Caracterización de la infección por el virus de la inmunodeficiencia humana en el Hospital Hermanos Ameinjeiras, 2002 - 2007
Authors: Velázquez Lores Lourdes María , Andrade Tacuri Grey Marilú , Triana Santana Gabriela Gricel , Ayala Briones Joselyn Aideé
Published: April 2019

La infección por el virus de la inmunodeficiencia humana es una epidemia mundial que afecta a más de 40 millones de personas en todo el planeta, con un alto índice de morbilidad y mortalidad por enfermedades oportunistas asociadas a estadios avanzados de la enfermedad. En Cuba la incidencia de esta infección es de 9.9 x 100000 habitantes y la prevalencia de 0.09%, siendo los registros más bajos del área del Caribe.

Se realizó un estudio retrospectivo, observacional y descriptivo para conocer las característica clínicas y epidemiológicas del grupo de pacientes diagnosticados con el virus de la inmunodeficiencia humana entre los años 2002 al 2007 en el hospital Hermanos Amejjeiras.

Se diagnosticaron en el centro 80 casos que fueron confirmados en el laboratorio de referencia (LISIDA), 58 de forma ambulatoria y 22 ingresados. En el año 2007 se diagnosticaron el 25% de los pacientes de la muestra, siendo el periodo de mayor número de casos. Los elementos epidemiológicos de mayor importancia fueron: el sexo masculino y la procedencia de la Ciudad de la Habana. Los sín- tomas clínicos más frecuentes fueron: linfadenopatías (58.3%), pérdida de peso (58.3%), astenia (50%) y diarreas (41.3%). Se diagnosticaron 9 pacientes con retrovirosis aguda, 9 en estadio SIDA y 4 como hallazgo en periodo de portador asintomático.

Las enfermedades relacionadas con SIDA que se diagnosticaron en esta serie fueron: La tuberculosis pulmonar (2 casos), el síndrome de desgaste por VIH (2 casos), Linfoma no Hodgkin de alto grado tipo Burkitt (1 caso), candidiasis dise- minada (1 caso), Neumonía por Pneumocistys carinii (2 casos) y toxoplasmosis cerebral (1 casos).
Frecuencia de Macrosomía Neonatal en mujeres embarazadas con Diabetes Gestacional en el Hospital Vicente Corral Moscoso. Cuenca Ecuador, en el periodo 2009-2014
Authors: Cobos Juana Karina , Rodas Mosquera Juan Enrique , Carrión Crespo Johana Carolina
Published: April 2019

El objetivo de esta investigación consideró determinar la frecuencia de macrosomía neonatal en mujeres embarazadas con diagnóstico de Diabetes Gestacional en el Hospital Vicente Corral Moscoso en el periodo 2009-2014. El tipo de estudio fue cuantitativo, descriptivo y retrospectivo realizado en base a revisión de 106 historias clínicas, se procesó la información con Microsoft Excel 2010, se obtuvieron frecuencias y porcentajes y se elaboraron tablas simples y gráficos. Los resultados evidenciaron que la edad materna predominante fue mayor de 30 años (39%), en edad gestacional el 58% se encontró entre las 42 o más semanas, el 75% de los productos  presentaron tendencia a la macrosomía con valores iguales o mayores a 3999 gramos al nacer, en el sexo neonatal entre hombres y mujeres se encontró un porcentaje de 53% y 47% respectivamente, hubieron 90 partos vaginales (85%) y 16 cesáreas (15%) según el peso materno el 30% se encontró en el grupo de 81 a 90 Kg y el 13% en más de 91 Kg Conclusión: Las tres cuartas partes de embarazadas con Diabetes Gestacional del grupo de estudio tuvieron productos con macrosomía fetal
The H19/let-7 feedback loop contributes to developmental dysplasia and dislocation of the hip
Authors: Ning B. , Jin R. , Wang D. , Sun J.
Published: April 2019

Developmental dysplasia and dislocation of the hip (DDH) is the most common type of lower limb deformity in pediatric orthopedics. The mechanism of the signaling pathway has been studied in depth. However, the role of epigenetic regulation, such as lncRNA, is still far from clear. In this study, we successfully established a rat model of DDH and demonstrated that H19 was down-regulated in the development of DDH. Further, we constructed H19 knockdown (KD) and overexpression chondrocytes. H19 KD suppressed the proliferation of normal chondrocytes, while overexpression of H19 promoted cell proliferation of DDH chondrocytes. Finally, we revealed that H19 bound to let-7 and inhibited its function, acting as a competing endogenous RNA. Down-regulation of H19 is closely associated with DDH progression and H19 is an important epigenetic factor that regulates the proliferation of chondrocytes. H19 may thus be a potential clinical marker for DDH diagnosis and treatment.
Participation of opioid receptors in the cytoprotective effect of chronic normobaric hypoxia
Authors: Naryzhnaya N.V. , Khaliulin I. , Lishmanov Y.B. , Suleiman M.S. , Tsibulnikov S.Y. , Kolar F. , Maslov L.N.
Published: April 2019

We studied the role of the delta, micro, and kappa opioid receptor (OR) subtypes in the cardioprotective effect of chronic continuous normobaric hypoxia (CNH) in the model of acuteanoxia-reoxygenation of isolated cardiomyocytes. Adaptation of rats to CNH was performed by their exposure to atmosphere containing 12% of O(2) for 21 days. Anoxia-reoxygenation of cardiomyocytes isolated from normoxiccontrol rats caused the death of 51 % of cells and lactate dehydrogenase (LDH) release. Adaptation of rats to CNH resulted in the anoxia/reoxygenation-induced cardiomyocyte death of only 38 %, and reduced the LDH release by 25 %. Pre-incubation of the cells with either the non-selective OR (opioid receptor) blocker naloxone (300 nM/l), the delta OR antagonist TIPP(psi) (30 nM/l), the selective delta(2) OR antagonist naltriben (1 nM/l) or the micro OR antagonist CTAP (100 nM/l) for 25 minutes before anoxia abolished the reduction of cell death and LDH release afforded by CNH. The antagonist of delta(1) OR BNTX (1 nM/l) or the kappa OR antagonist nor-binaltorphimine (3 nM/l) did not influence the cytoprotective effects of CNH. Taken together, the cytoprotective effect of CNH is associated with the activation of the delta(2) and micro OR localized on cardiomyocytes.
Gastrointestinal Non-Motor Dysfunction in Parkinson’s Disease Model Rats with 6-hydroxydopamine
Authors: Feng Xiao-Yan , Yan Jing-Ting , Zhang Xiao-Li , Zhu Jin-Xia
Published: April 2019

Parkinson's disease (PD) is a neurodegenerative disease with a progressive loss of mesencephalic dopaminergic neurons of the substantia nigra (SN). To further evaluate its pathophysiology, accurate animal models are needed. The current study aims to verify the impact of a 6-hydroxydopamine (6-OHDA) bilateral microinjection into the SN on gastrointestinal symptoms in rats and confirm that the 6-OHDA rat model is an appropriate tool to investigate the mechanisms of Parkinsonian GI disorders. Immunohistochemistry, digital X-ray imaging, short-circuit current, FITC-dextran permeability and ultra-performance liquid chromatography tandem mass spectrometry were used in this study. The results indicated that the dopaminergic neurons in SN and fibres in the striatum were markedly reduced in 6-OHDA rats. The 6-OHDA rats manifested reductions in occupancy in a rotarod test and increases in daily food debris but no difference in body mass or daily consumption. Compared with control rats, faecal pellets and their contents were significantly decreased, whereas gastric emptying and intestinal transport were delayed in 6-OHDA rats. The increased in vivo FITC-dextran permeability and decreased intestinal transepithelial resistance in the model suggest attenuated barrier function in the digestive tract in the PD model. Moreover, inflammatory factors in the plasma showed that pro-inflammatory factors IL-1β and IL-8 were significantly increased in 6-OHDA rats. Collectively, these findings indicate that the model is an interesting experimental tool to investigate the mechanisms involved in the progression of gastrointestinal dysfunction in PD.
The absence of sympathoexcitation during the development of hypertension in Cyp1a1 Ren-2 transgenic rats
Authors: Zicha J. , Hojná J. , Kopkan L. , Červenka L. , Vaněčková I.
Published: April 2019

The insertion of mouse renin gene (Ren-2) into the genome of normotensive rats causes a spontaneous rise of blood pressure (BP), leading to an angiotensin II (Ang II)-dependent form of hypertension in transgenic (mRen-2)27 rats (TGR). However, enhanced sympathetic BP component was demonstrated in heterozygous TGR aged 20 weeks. In the present study we used another model, i.e. Cyp1a1-Ren-2 transgenic rats (iTGR) in which hypertension can be induced by natural xenobiotic indole-3 carbinol (I3C) added to the diet. We investigated whether the development of high blood pressure (BP) in 5-month-old iTGR animals fed I3C diet for 10 days is solely due to enhanced Ang II-dependent vasoconstriction or whether enhanced sympathetic vasoconstriction also participates in BP maintenance in this form of hypertension. Using acute sequential blockade of renin-angiotensin system (RAS), sympathetic nervous system (SNS) and NO synthase (NOS) we have demonstrated that the observed gradual increase of BP in iTGR fed I3C diet was entirely due to the augmentation of Ang II-dependent BP component without significant changes of sympathetic BP component. Thus, the hypertension in iTGR resembles to that of homozygous TGR in which high BP was entirely dependent on Ang II-dependent vasoconstriction. Moreover, our measurements of acute BP response to Rho kinase inhibitor fasudil in animals subjected to a combined blockade of RAS, SNS and NOS indicated the attenuation of basal calcium sensitization in both iTGR and homozygous TGR.
THE EFFECTS OF DIET, PHYSICAL ACTIVITY AND SOCIAL FACTORS ON STRESS PERCEIVED BY STUDENTS
Authors: Vizbaraitė Daiva , Morkūnaitė Raminta
Published: April 2019

Backgroud. General health status of students is becoming worse due to an intensive lifestyle: a difficult job or
study routine, improper diet, and low physical activity (Poteliūnienė, 2010). One of the common problems among
students is stress. Stressful situations on a daily basis have been found to be associated with a worse physical
and psychological status, harmful habits or personal relationships with friends (Dusselier, Dunn, Wang, Shelley, &
Whalen, 2005; Leppink, Odlaug, Lust, Christenson, & Grant, 2016).
Methods. According to the following questionnaires, dietary habits and some social peculiarities (Grabauskas,
Zaborskis, Klumbienė, Petkevičienė, & Žemaitienė, 2004), physical activity (Aadahl & JØrgensen, 2003) and
perceived stress (Konduri, Gupchup, Borrego, & Worley-Louis, 2006) by female and male students were determined.
The data obtained were processed using mathematical statistical methods. The relationships between qualitative
determinants were evaluated by chi square (χ 2 ) criterion. A value at p < .05 was considered significant. Statistical
analysis was performed using SPSS (version 17.0) (Statistical Package for Social Science 17.0 for Windows)
statistical software package.
Results. Male students (54.2%) who were following a dietary regime reported experiencing low level of stress,
and those students (45.2%) who were not having a dietary regime perceived moderate level of stress. Married female
students (80%) responded that they experienced low level of stress, moderate level of stress was indicated by 72.7%
of females living with a partner and 40% of females who had a boyfriend, and 38.5% of single females reported
having high level of stress.
Conclusions. Male students who were following a dietary regimen reported experiencing lower level of stress,
and those students who were not having a dietary regimen responded that they perceived moderate level of stress.
A dietary regimen and perceived stress did not differ among female students. Different levels of physical activity
were not associated with stress experienced by female and male students (p > .05). Married female students did not
perceive high level of stress; moderate level was reported by females living with a partner; high level of stress – by
single students. Marital status and perceived stress did not differ in male students.
Four Narratives and a Baby: An Adoption Reunion Story
Authors: Wilson Harris Helen , Hale Jennifer R , Oldham Beth , Powell Caitlin
Published: April 2019

In 1992, a 19-year-old single mother of one made the decision to place her second child, a newborn, for adoption. This qualitative exploration of adoption issues is written, in part, in first person by the authors: the birthmother, the daughter she raised, the daughter she placed, and the adoptive mother. The article explores adoption reunion, adoption literature, and a scriptural adoption narrative for themes and for recommendations. The authors address negative stereotypes around adoption, the common theme of loss in all parties, and the potential for healing in reunion through life stage changes, including marriage and the next generation. This is a unique opportunity to hear the multiple voices of adoption in one narrative.
Ziver Paşa-zâde Yusuf Bahâeddin’in Torunu İçin Yazdığı Mensur Bir Mersiye: Sünûsî-i Asgar
Authors: KAYAOKAY İlyas
Published: April 2019

Bu çalışmada Türk edebiyatında
türüne ve konusuna çok fazla rastlanılmayan mensur bir mersiyenin tanıtımı yapılacaktır.
Söz konusu Sünûsî-i Asgar adlı mensur mersiye, meşhur Ziver Paşa’nın oğlu Yusuf
Bahâeddin tarafından küçük yaşta ölen torunu için yazılmıştır. Eser, torununun ölüm
tarihi olan 1329/1914 yılında kaleme alınmış ve bir yıl sonra da Matbaa-i Osmaniye’de
bastırılmıştır. 14 sayfalık bu eserin son kısmında, çaprazlama nazım şekliyle
yazılmış yedi dörtlükten oluşan manzum bir mersiye de kayıtlıdır. Eserdeki
ifadelerden anlaşıldığına göre; Sünûsî, Yusuf Bahâeddin’in kızının çocuğudur ve
iki yahut üç yaşında iken ağır bir soğuk algınlığı neticesinde hastalanarak
vefat etmiştir. Yusuf Bahâeddin’in sade, anlaşılır ve samimi bir dille çektiği ıztırabı
dile getiren bu mensur mersiye, Âkif Paşa’nın torunu için yazdığı mersiyeden
sonra yazılmış bu sahadaki ikinci mersiye olması yönüyle önemli bir metindir.
Eserde Sünûsî’nin teyzesi kızı Betül ile birlikte çektirmiş olduğu bir fotoğrafının
yer alması, eseri ilginç kılan bir diğer özelliktir. Makalemizde edebiyat
tarihlerinde anılmayan bu eserin tanıtımı ve Arap harflerinden Latin alfabesine
aktarımı yapılacaktır.
Sergüzeştnâmeden Hatırata Geçiş Eseri: Mihnet-Keşân
Authors: BABACAN İsrafil
Published: April 2019

Klâsik Türk Edebiyatı’nda gerçekçi anlatıma sahip
hatıra esaslı türlere ve anlatım biçimlerine çok sık rastlanmadığı bir
gerçektir. Aslında bütün Doğu ve İslam edebiyatlarında durum bundan farksızdır.
Söz konusu yoksunluğun İslam kültüründeki temel nedeni, birey ile bireye ait
dünyevî rabıtaların dile getirilmesinin din ve tasavvufça hoş
karşılanmamasıdır. Ayrıca yüzyıllarca eleştiriye kapalı siyasal ve sosyal yapı
içinde yaşamak da önemli bir etkendir. Fakat modern manada olmasa da
tezkireler, geleneksel tarih, vekâyinâme, gazavatnâme, seyahatnâme ve benzeri
türden eserlerde, dağınık ama önemli anılara rastlamak mümkündür. Klâsik Türk şiirinde geleneksel türlere nispetle
daha gerçekçi anlatıma sahip sergüzeştnâmeler, genellikle mesnevî nazım
şekliyle manzum kaleme alınan edebî ürünlerdir. XV. yüzyıldan XIX. yüzyıla
kadar kesintisiz biçimde vücuda getirilen bu türden eserlerde, göreceli bir
realizm ön plandadır. Ancak bu durum, XIX. asır edebiyatımızda Batılılaşma ile
birlikte ortaya çıkan pozitivist gerçeklilikle mukayese edilemez. Bununla birlikte, XIX. yüzyılın başında siyasî
nedenlerle İstanbul’dan Keşan’a sürülen Keçecizâde İzzet Molla’nın (ö. 1829)
yaklaşık bir yıl süren sürgün hayatı sırasında, 1823-1824 yılları arasında
kaleme aldığı Mihnet-Keşân adlı mesnevisi, dikkat çekici bazı yenilikler
içerir. Eserde şekil açısından geleneksel mesnevilerde görülmeyen çeşitli
niteliklerle birlikte, gerçekçi tasvirler, kronolojik olay örgüleri, realist
zaman-mekân-şahıs dizini, modern hikâyeleri andıran dönüşlülük ve psikolojik
tahlilden hareketle oluşturulan anlatım tarzı, onu aynı dönemde kaleme alınan
mesnevilerden tür ve şekil açısından farklı kılar.

Bu farklılıklar, Mihnet-Keşân’ı, edebiyatımızda
hatırat türünün öncüsü sayılabilecek bir niteliğe taşımıştır. Biz çalışmamızda
Mihnet-Keşân’ı, bir yönüyle klâsik mesnevî olması açısından Divan şiiri
araştırmaları yöntemleriyle ve başka bir bakışla modern hatırat nitelikleri
taşıması dolayısıyla yeni metotlarla inceleyeceğiz. İnceleme sonunda, söz
konusu eserin, modern hatırat türünün edebiyatımızda ortaya çıkışına nasıl
öncülük ettiğini açıklığa kavuşturmaya çalışacağız.
Şeyh Murtaza Sükûtî Baba Divanı ve Nüshaları
Authors: KARAYİĞİT Atiye Buket
Published: April 2019

Murtaza Sükutî Baba, Üsküplü
mutasavvıf bir şairdir. Şiirlerini herhangi bir sanat kaygısı gütmeksizin bir
araç olarak kullanmıştır. Divanı, bilinen tek eseridir. Şiirlerini sade bir Türkçeyle
kaleme alan Sükutî, hem aruz hem de hece ölçüsünü kullanmıştır. Divandaki şiirlerin
dini-tasavvufi bir anlayışla kaleme alındığı görülmektedir. Sa’diyye tarikatına mensup
olan Sükutî’nin divanı, 2011 yılında Nurgül Özcan tarafından yüksek lisans tezi
olarak yayımlanmıştır. Metin ve inceleme olarak yayımlanan bu çalışmada Özcan,
divanın aslının Almanya’da “Tübinger depot der Staatsbibliothek”te bulunduğu
kaydeder.

Suat Yaman (S.Y.) nüshası ile
Almanya (A.) nüshasının farklı nüshalar olduğu tezinden hareketle bu çalışma
yapılmıştır. Bu makalede önce Sükutî’nin hayatı ve edebi kişiliğinden
bahsedilecek, her iki nüshadan da belli ölçüde söz edildikten sonra dil ve üslup
özelliklerine kısaca değinilecektir. Çalışmada asıl amaç Sükutî divanının S.Y.
nüshasının genel bir resmini çizmektir. Bu amaçla ilgili nüshadan çeşitli örnekler
verilecek, açıklamalar yapılacaktır.