bluuebunny/crossref_metadata_2025 huggingface dataset:
“However, he did not switch to walking”: the experience of a philosophical research of collective endurance running
Authors: Kannykin Stanislav Vladimirovich
Published: August 2021

The object of this research is the collective endurance running as a social phenomenon of the XX – XXI centuries. The subject of this research is the spiritual grounds of the person’s choice and the sociocultural components of the existence of collective endurance running viewed in their interrelation. The article leans on the scientific approach and general methodological principles of scientific study, dialectical method, as well as ideas and values of the concept of humanism. The author set the following tasks: determine the social grounds and factors of proliferation endurance running in contemporary history; explore the peculiarities of interaction between running locomotion and unconscious aspect of the personality of amateur athlete; explicate the impact of long-distance running upon metaphysical component of the spiritual world of a “running” person; outline the social needs fulfilled by cultivation and propaganda of the positive impact of long-distance running practices; determine the problematic field of the “philosophy of running”. The novelty of this work lies in description of the worldview foundations of running activity of the amateur long-distance runners. These foundations are viewed as the main reason for proliferation of endurance running in modern society, as well as the semantic core of the problematic field of the “philosophy of running”. The metaphysical component of mentality of the “running” person via a long running effort goes back to the transcendent beginning of its existence; amateur endurance running provides selection of the most effective adaptive skills; forms an autotelic personality oriented towards the mode of “being”, rather than “possessing”; serves as a component of environmental movements and charity campaigns, a form of socialization of people with impairments; has a powerful educational potential. Being the basis of most athletic movements, running can be viewed as the “initial cell” that determines the impact of sport practices upon the human mind and body, as well as the current stage of social development. In relation to a human, such impact can be described by the word “kalokagathia”, while in relation to society – by the terms “humanism” "and “democracy”.
The phenomenon of loneliness among senior citizens: subject of discussion
Authors: Akutina Svetlana Petrovna , Stolyarova Elena Valentinovna
Published: August 2021

The subject of this research is the phenomenon of loneliness among senior citizens. The goal lies in examination of the problems of loneliness among senior citizens. The article reviews such aspects as alienation from the society, feeling useless and helpless; gives the key characteristics of loneliness – assessment of social status, type of inferiority, type of temporal perspective, models of loneliness. The types of loneliness are divided into situational, chronic, recurrent, as well as emotional and social isolation. Research methodology employs the ideas of phenomenological, systemic, and activity approaches in the context of studying the problems of loneliness among senior citizens and effective ways of their solution. The survey revealed that senior citizens quite often feel lonely, which is reflected in the distorted interaction with other people, experiencing psychological problems, difficulties in self-organization, and the need for assistance of the social workers. The author empirically proves that the developed program “Young at Heart”, through creating hobby groups, helps senior citizens to feel needed in the society, improves their psychoemotional state, and allows overcoming loneliness. The article examines the theoretical approaches towards comprehension of the problem of loneliness among senior citizens. The author formulates the original definition of the concept of “loneliness” in the context of socio-psychological aspect, determines the causes of the phenomenon of loneliness among senior citizens within the framework of their interaction with society, develops a questionnaire aimed at studying the factors of socio-psychological loneliness of senior citizens, offers the ways for overcoming loneliness through active social life, such as  creation of the hobby group “Young at Heart”, which includes the three types of activity: leisure and creative-applied, health promotion,  and garden therapy. It is substantiated that maintenance of zest for living among senior citizens would be effective by creating a socially favorable, psychoemotional and health-preserving environment in the society.
The role of public and private initiatives in the development of public education in Minusinsk District of Yenisei Province in the late XIX – early XX centuries
Authors: Zlotnikova Svetlana Zlotnikova Gennad'evna
Published: August 2021

The subject of this research is public and private initiatives of the population in the development of public education in the Minusinsk District of Yenisei Province in the late XIX – early XX centuries. The goal consists in studying the role of public and private initiatives in the development of public education in the territory of Minusinsk District of Yenisei Province over the period under review. The article employs the cultural-historical and historical-geographical methods; historiographical framework is comprised of the materials of pre-revolutionary periodical press (the newspaper “Eastern Review”), statistical data of Reviews of Yenisei Province, archival documents of the Minusinsk State Archive, and published documentation. Special attention is given to charitable activity of such individuals as I. G. Gusev, V. A. Danilov, F. F. Devyatov, N. M. Martyanov, I. M. Sibiryakov, and others in the sphere of public education. The article reviews the role of the Board of Regents of Minusinsk Women's Professional Gymnasium and Minusinsk Society for the Monitoring of Elementary Education on the issue of literacy of the local population. The conclusion is made that the autonomous socially important activity of the representatives of merchantry and peasantry, as well as nongovernmental organizations, contributed to an increase in the number of schools, improvement of financial situation of educational institutions of Minusinsk District, and attraction competent pedagogues to the Siberian province.
Food supply service of the Russian army in the Seven Years' War (1756–1763)
Authors: Tkachenko Il'ya Yur'evich
Published: August 2021

This article discusses the events of the Seven Years' War from the perspective of supplying the troops of the Russian army with food and adapting it to the European military campaign. An overview is given to the key battles of the Seven Years' War, reflecting the nutrition of troops and activity of certain individuals on maintaining military capability of the army. The author also touches upon the fate of A. V. Suvorov and the beginning of his service as a supply officer, which left an imprint on his future career. The article is based mostly on archival materials of the Russian State Archive of the Ancient Acts, as well as literary sources of scientific nature. The article describes the time of the dawn of the absolutist Russian State, being a powerful international force. The history of food service on the example of the Seven Years’ War of 1756– 1763 is dedicated to the history of food supply of the Russian army and population throughout the Seven Years' War (1756–1763), the main type of supply changed depending on the financial situation of the state. The history of food service in Russia is one of the most remarkable pages in military history. Food service, which established with the advent of the Russian regular army, has been one of the main vectors of activity of the military department for centuries.
Assessment of the factors contributing to the formation of regional budget of the Khanty-Mansi Autonomous Okrug –Yugra
Authors: Muratova Svetlana Railovna , Bukanova Roza Gafarovna
Published: August 2021

The relevance of this research is substantiated by the currently growing role of financial relations in the formation and execution of budgets of the constituent entities of the Russian Federation. The formation and implementation of budgetary policy of the Russian Federation determines the economic and financial framework for functionality of the region and life of the society as a whole. The goal is to assess the factors contributing to the formation of regional budget of the Khanty-Mansi Autonomous Okrug – Yugra. The subject of this research is the revenues and expenditures of the budget of Khanty -Mansi Autonomous Okrug – Yugra. Practical importance of the conducted research lies in the obtained results that allow the regional budgets to choose the way for improving budget security. The information base is comprised of the scientific works of Russian and foreign authors, educational-methodological publications, materials of the scientific conferences dedicated to the formation of regional budgets, legislative and normative acts of the Russian Federation,, reference materials of the Federal State Statistics Service Of the Russian Federation. The main conclusion consists in determination of the factors influencing the regional budget of the Khanty-Mansi Autonomous Okrug – Yugra. The author's special contribution lies in evaluation of the specificity of formation of budget of the Khanty-Mansi Autonomous Okrug – Yugra, as well as the methods aimed at minimization of budget risks for solution of the regional budgetary problems. The formulated recommendations for increasing budget security would promote the innovative development and improvement of budgetary and tax relations of the regional budgets. The theoretical significance consists in advancement of the theory of regional economy. The acquired results can be applied in theoretical substantiation of the strategic tasks of managing regional budgets.
Adaptation of Iranian and Semitic loanwords in the Ancient Greek language: 'garden' / ' garden of Eden’ (on the example of the lexemes παράδεισος and a number of γάνος-γανναθ — (αλ)γοναιναθ)
Authors: Davydov Tycho , Gorshkov Andrey Ivanovich
Published: August 2021

The object of this research is the problems of functionality of Iranian and Semitic loanwords in the Ancient Greek language, while the subject is the lexemes παράδεισος, γάνος, γανναθ, (αλ)γοναιναθ. The authors meticulously examine such aspects of the topic as the morphological and phonetic assimilation of foreign language lexicon, nonobservance of phonotactics of the Greek language, impact of folk etymology upon the word form , absence of diacritics in conveying Semitic borrowings in the Greek language. Special attention is given  to the problems of etymologization, nuances of dictionary definitions throughout different periods: classical, Hellenistic, Hellenistic-Roman, Late Antique, and Byzantine. It is noted that over time, close ties with barbarian peoples affected the Greek language itself. The main conclusion consists in determination of the gradation of lexemes under review in accordance with the degree of their adaptation to the Greek phonetics and phonotactics, as well as morphology. The author's special contribution to this research consists in proving the results and conclusions of a range of previous studies, as well as in critical coverage of the controversial concepts. The novelty lies in the proposed etymology of the lexeme παράδεισος, and the new interpretation of its vocalism. The relevance of this work lies in involving rare lexicon, which previously has not received due attention within the existing scientific tradition.
LEARNING SKILLS FORMATION AMONG PRIMARY SCHOOL STUDENTS IN THE PROCESS OF NETWORK INTERACTION AT COMPUTER SCIENCE LESSONS
Authors:   Grammar School No. 9 (Krasnoyarsk, Russia), Potupchik E.G. , Simonova A.L. ,   KSPU named after V.P. Astafiev, Lomasko P.S. ,   KSPU named after V.P. Astafiev
Published: August 2021

Statement of the problem. This article discusses the problem of universal learning skills (ULS) assessment among primary schoolchildren in the process of network interaction during computer science lesson activities. The research problem is determined by the requirements of the modern information society and becomes especially relevant in the context of the transition to distance learning in connection with the Covid-19 pandemic in 2020. The purpose of the article is to give scientific grounds and description of the assessment means for identifying the ULS formation level among primary schoolchildren at computer science lessons in the process of network interaction. The research methodology is based on the analysis and synthesis of regulatory documents on primary school education, research works of Russian and foreign scientists on the problem of digital socialization of generation Z and the organization of distance learning in the context of the Covid-19 pandemic; analysis of research in the field of networking; analysis of research in the field of ULS diagnostics among students. Research results. We described a method for communicative and regulatory ULS assessment formed among primary schoolchildren of the fourth grade at computer science lessons during the stage of network interaction using Google cloud services. The proposed method based on the level model of network interaction among primary school students was tested in Gymnasium No. 9 in Krasnoyarsk and School No. 11 in Abakan from 2016 to 2019. In total, the study covered 120 students over three years. Conclusion. As a result of our study, we have come to the conclusion that organization of network interaction based on distributed groups in space according to the level model contributes to the ULS formation of the basic and advanced levels that is confirmed by the results of their assessment. The materials presented in the article can be used by both elementary school teachers and subject teachers at the level of primary school education, as well as by methodologists and school administration to assess the ULS among students.
METHODOLOGY FOR TEACHING AN INTERDISCIPLINARY COURSE IN ECOLOGY IN 5TH–9TH GRADES OF A SECONDARY SCHOOL
Authors:   Secondary School Nо. 45 (Novosibirsk, Russia), Robskikh E.A. , Makarova O.B. ,   Novosibirsk State Pedagogical University, Galkina E.A. ,   KSPU named after V.P. Astafiev
Published: August 2021

Statement of the problem. The relevance of the study is determined by the social order of modern society for the training of students who are able to quickly adapt to changing environment, apply the knowledge gained in practice, and be active in mastering educational material. All of this can be achieved with the help of interdisciplinary academic courses that contribute to the achievement of metadisciplinary results required by the Federal State Educational Standard of Basic General Education. The pedagogical experiment was aimed at testing and evaluating the effectiveness of this method. The purpose of the article is to develop a methodology for teaching an interdisciplinary course in Ecology in the 5th–9th grades of a secondary school and to experimentally prove its efficacy. The research methodology consists of the analysis and synthesis of normative legal documents in the field of basic general education, scientific works of foreign and Russian scientists, experience in teaching Ecology in the 5th–9th grades. Research results. An interdisciplinary academic course in Ecology for the 5th–9th grades was developed and tested, the indicators of qualitative and quantitative performance of students before and after studying the course were analyzed. Conclusion. The interdisciplinary academic course in Ecology for the 5th–9th grades includes elements of N.B. Shumakova’s interdisciplinary teaching methodology and the following integrated concepts: system, science, force, adaptation, and interconnection. The scientific novelty of the study lies in the proof that interdisciplinary interaction in a general education institution allows achieving meta-disciplinary educational results that increase the quality of academic performance.
FORMATION OF STUDENTS’ READINESS FOR INDEPENDENT WORK WITH A TEXT THROUGH DISTANCE EDUCATIONAL TECHNOLOGIES APPLIED IN TEACHING A FOREIGN LANGUAGE
Authors:   KSPU named after V.P. Astafiev, Yanova M.G. , Olentsova Yu.A. ,   Krasnoyarsk State Agrarian University
Published: August 2021

Statement of the problem. The article studies the problem of formation of students’ readiness for independent work when studying a foreign language. The article substantiates the necessity of using distance learning technologies for the effective organization of students’ independent work in foreign language classes. The article analyzes the work with a foreign text in the formation of students’ readiness for independent work through distance educational technologies. The purpose of the article is to identify methods and tools for step-by-step work on the text of a foreign language through distance educational technologies for the formation of students’ readiness for independent work. The methodology is based on the analysis and synthesis of the experience gained in science and practice of teaching a foreign language to students of various specializations. Research results. Based on the analysis of published scientific studies, the methods and tools of working with a text in a foreign language are identified. The choice of the methods and tools is determined by the purpose of the lesson, the type of text chosen for reading, and the stages of working with the text. A system of exercises for students’ independent work on the development of reading skills based on the electronic platform LMS Moodle is proposed. LMS Moodle has many tools for creating these exercises. One can select tools that correspond to the level of students’ training, the type of text and technical capabilities. Conclusion. The use of distance learning technologies in teaching a foreign language significantly increases the intensity of the educational process. It contributes to the formation of students’ readiness for independent work when learning a foreign language in general, and, in particular, when working with a text.
INDICATORS OF PSYCHOLOGICAL READINESS FOR MOTHERHOOD AND PSYCHOLOGICAL AND PEDAGOGICAL MEASURES FOR ITS FORMATION
Authors:   KSPU named after V.P. Astafiev, Lysenko O.F. , Safonova M.V. ,   KSPU named after V.P. Astafiev
Published: August 2021

Statement of the problem. The article presents an analysis and discussion of the results of diagnostic assessment among pregnant women, allowing us to draw conclusions on indicators of psychological preparedness for motherhood. The purpose the article is to outline the necessary areas of work with women on the way to the formation of the maternal sphere in ontogenesis. Materials and Methods. The research methodology consists of the concept of the formation of the “maternal need-motivation sphere” by G.G. Filippova, the theory of E.V. Matveeva about psychological readiness for motherhood, as well as the analysis and synthesis of studies on motherhood, psychological readiness for motherhood, questions of perinatal psychology, theory of psychological readiness for activity. The study involved 156 married pregnant women aged 25 to 35 with higher or secondary specialized education, with a pregnancy period of no less than 24 weeks. The following psychodiagnostic methods were applied: the projective drawing test “I and my child” by G.G. Filippova, the modified Dembo-Rubinstein scale by G.G. Filippova, test of the relationship of pregnant I.V. Dobryakov’s test on relationships for pregnant women, and the authors’ questionnaire for pregnant women. Research results. The diagnostic results indicate that 79,3 % of women examined are conditionally ready for motherhood, 15 % are not ready, and only 5,7 % of respondents can be considered psychologically ready for motherhood. The last group of women is characterized by unconditional acceptance of a child, themselves as a mother, and the situation of motherhood in general. The correlation and factor analysis of the obtained data made it possible to distinguish four groups of the most informative indicators of psychological readiness for motherhood in pregnant women: the peculiarities of the current situation of the woman, the mother-and-child system, family relations and the social and domestic situation. There are also widely presented factors that make it difficult to form a psychological readiness for motherhood: unfavorable experience of relationships with their own parents, difficulties in establishing emotional contact, lack of knowledge and experience in caring for children. There is a need to work with these aspects before pregnancy. Conclusions are drawn on the importance of comprehensive psychological and pedagogical support of a woman on the way to the formation of the maternal sphere of her personality in relation to genesis, which contributes to the development of psychological preparedness for motherhood.
Studying the Influence of Storage Conditions, 1-MCP, and Packaging Films on Quality of Sweet Dalilah Green and Red Stage Peppers (Capsicum annuum L.)
Authors:   San Luis Valley Research Center, Department of Horticulture and Landscape Architecture, Colorado State University, 0249 East County Road 9N Center, CO 81125, USA., Jayanty Sastry S. , Hamed Mansor , Bartolo Michael ,   Arkansas Valley Research Center, Department of Horticulture and Landscape Architecture Colorado State University, 27901 Co Rd 21, Rocky Ford, CO 81067, USA
Published: August 2021

Peppers are a popular fresh market commodity but have a limited shelf life. The present study evaluated the effects of storage time, packaging films, and 1-methylcyclopropene (1-MCP) on weight loss, firmness, respiration rate, ethylene production, ascorbic acid, antioxidant activity, and bioactive compounds of Sweet Delilah (Capsicum annuum). Four packaging films were tested in this study: polypropylene (P12F), laminated polynylon (30 NV), coextruded vacuum pouch (30 NVC), and polyethylene (P15G). Collectively, packaged peppers showed less weight loss than the control. When stored at the red stage, the firmness loss was 13 % in peppers that were treated with 1-MCP compared to 25% loss in the control samples. The most significant reduction in respiration rate in the red stage peppers was 0.88 ml kg-1 h-1 when packaged with 30NVC and 0.91 ml kg-1 h-1 when packaged with P15G, compared to 1.22 ml kg-1 h-1 for the control. The ranges of total phenolic and total flavonoid compounds were 3782 and 5090, respectively, in the green stage and 519 and 647 µg/g, respectively, in the green and red stages. When Sweet Delilah peppers that were treated with 1-MCP maintained higher levels of phenolic and flavonoid compounds than the control samples. Overall, the largest phenolic and flavonoid losses occurred from the control samples, while the smallest phenolic and flavonoid losses occurred from the packaged peppers. The highest ABTS activity was 150 µmol TE/g when packaged with P12G film, whereas the lowest ABTS activity was 143 µmol TE/g in the control samples in the red stage. Peppers packaged with 30NVC films retained higher ascorbic acid levels than peppers that were packaged with other films and the control samples. Keywords: Peppers, Phenolics, Flavonoids, Ascorbic acid, Antioxidant activity, Packaging.
Qualidade de vida, trabalho e apoio familiar de pessoas com fibromialgia
Authors: Mota Luana Maria Liborio da , Queiroz Mariane Silva , Castro Beatriz Tianeze de , Araújo Lorena Vieira Fernandez de , Leite Thais Oliveira , Balisa Bárbara Dielly Costa , Corrêa Shesllen Mikaelly Cruz , Oliveira Juliano Gusmão de , Correia Fernanda Sales Alves , Lessa Rosângela Souza
Published: August 2021

Objetivo: Avaliar a qualidade de vida, o trabalho e o apoio familiar em pessoas com fibromialgia. Métodos: Trata-se de um estudo de corte transversal, com abrodagem quantitativa, com 102 fibromiálgicos. A coleta de dados ocorreu por meio de um questionário online composto por perguntas sobre perfil sociodemográfico e apoio familiar e o Questionário sobre o Impacto da Fibromialgia (QIF). Os dados quantitativos foram oriundos da ferramenta Google Forms e salvo em tabela do Microsoft Excel ®. O estudo foi aprovado por Comitê de Ética em Pesquisa.  Resultados: Obteve-se dessa amostra um predomínio do sexo feminino 97,1%, 63,7% era pardo, 68,6% casado ou em união consensual/estável e 45,1% com escolaridade até o ensino médio. Quanto às atividades remuneradas 65,7% responderam estar trabalhando. Na avaliação global do QIF atingiram uma média de 75,70 ± 16,71 indicando elevado comprometimento da qualidade de vida. Conclusão: É preciso, então, atenção à saúde e ao bem-estar do fibromiálgico, compreensão familiar, empatia dos profissionais de saúde e novos estudos acerca da doença.
“Mucormycosis” and coronavirus disease 2019: An epidemic within the larger pandemic
Authors: Shukla Sangeeta , Gupta Manisha , Agarwal Neha , Shukla Rishi
Published: August 2021

India is passing through a significant impact of Wuhan origin coronavirus disease 2019 (COVID-19) pandemic in the second wave. Mucormycosis is emerging as a larger problem for our patients as compared to the first wave. Several plausible explanations have been put forth –but none has been proven as yet. We herein report eight cases of COVID-19-associated rhino-orbital mucormycosis diagnosed and managed at our center. We observed a higher risk among middle-aged men, with known or covert diabetes who received high-dose steroids and/or prolonged oxygen for COVID-19 management.
Riskli gebelerin doğum korkusu, emzirme özyeterlilik ve emzirme başarılarının belirlenmesi
Authors: INAN KIRMIZIGÜL Ebru , ŞAHİN Sevil , TUNCAY YILMAZ Semra , SAHİN Dilek
Published: August 2021

Amaç: Bu çalışmada, yüksek riskli gebelerin doğum korkusu, emzirme özyeterlilik ve emzirme başarısı arasındaki ilişkinin değerlendirilmesi amaçlanmıştır.
Gereç ve Yöntem: Kesitsel ve tanımlayıcı tipte yapılan çalışma Ankara’da bir eğitim araştırma hastanesinde Ocak-Kasım 2017 tarihleri arasında perinatoloji servisine doğum amaçlı yatan gebelere uygulanmıştır. 326 gebe ile çalışma tamamlanmıştır. Çalışmaya katılan tüm gebelerden yazılı ve sözlü onam alındıktan sonra, anket form (sosyo demografik, obstetrik, geçmiş emzirme deneyimi ve doğum eylemi süreciyle ilgili özellikler) yüzyüze doldurulmuştur. Doğum Korkusu Ölçeği (DKÖ), servikal dilatasyon 3cm (DKÖ-1), 6 cm (DKÖ-2) ve 9 cm iken (DKÖ-3), Emzirme Öz-Yeterlilik Ölçeği (EÖYÖ) ve Latch Emzirmeyi Değerlendirme ve Tanılama Ölçeği (LATCH) kullanılmıştır.
Bulgular: Çalışmaya katılan tüm gebelerde DKÖ puan ortalaması 37,92±6,87 olarak bulunmuştur. Herhangi bir işte çalışmayan, geliri giderinden düşük olan, kronik bir rahatsızlığı olan gebelerde DKÖ puan ortalaması daha yüksek bulunmuştur (p<0,05). Çalışmada DKÖ-1 puan ortalaması 43,40±8,28, DKÖ-2 puan ortalaması 37,49±7,89, DKÖ-3 puan ortalaması 32,87±8,69 olarak tesbit edilmiştir. Ölçümler arasında farkın istatistiksel olarak anlamlı olduğu bulunmuştur (p<0,001). Çalışmada DKÖ puan ortalaması ile EÖYÖ puan ortalaması arasında istatistiksel olarak anlamlı bir ilişkinin olmadığı (p=0,199, r=-0,071), LATCH puan ortalaması ile pozitif yönlü ilişkisinin olduğu (p<0,001, r=0,229) saptanmıştır.
Sonuç: Yüksek düzeyde doğum korkusu yaşayan annelerin emzirme başarılarının daha düşük olduğu tesbit edilmiştir. Bu kapsamda, doğum öncesi dönemde gebelerin doğuma hazırlık eğitimine katılarak; gebelik, doğum, postpartum dönem ve emzirme konularında destek alması önerilmektedir.
Lignin peroxidase: Optimization of media for higher productivity by single factor optimization method
Authors: Shukla Shruti , Padhiar Anjali
Published: August 2021

Lignin peroxidase belongs to ligninolytic enzyme group and is one of the industrial important enzymes as it has wide applications in different sectors. Lignin peroxidase is produced by submerged fermentation process which requires optimization of physical and chemical parameters to achieve higher activity and make the process cost effective. The present study aimed at the optimization of physical as well chemical parameters of production medium. The optimization includes physical parameter such as incubation time, inoculum size, temperature, pH, RPM (Rotation per minute) while chemical parameters include carbon source, nitrogen source and different mineral elements. Form the optimization study, it was observed that highest lignin peroxidase production was achieved after 72 hours of incubation at temperature 300C, pH 6 and RPM 120. Optimization of chemical parameters reveals that incorporation of sodium nitrite (9g/L) in the media gave significant increase in enzyme activity. It was found that the maximum productivity achieved after optimization was 2214 U/ml which was four times higher than process without optimized parameters.
String Analysis to identify the Activity of Gyrinops versteegii derived Lauric Acid against Breast Cancer
Authors: Hidayati Lisna , Ridwan Nur Fathurahman , Margiyanti Nova Eka , Ramadhani Anggia Noor , Wardana Taufik Adhi Prasetya , Nuringtyas Tri Rini
Published: August 2021

Understanding the interactions between cellular proteins and compounds from agarwood (Gyrinops versteegii) could lead to effective approaches for the diagnosis and treatment of breast cancer. In this study, we aimed to identify the interaction between lauric acid, a compound derived from agarwood (G. versteegii) and its target proteins using String database analysis. String analysis showed that lauric acid affects cellular proliferation through interactions with the Androgen Receptor (AR) and binds to Aldo-Keto Reductase (AKR1C3). Lauric acid also interacted with mitogen-activated protein kinase 1 (MAPK1) and other proteins such as matrix metalloprotein (MMP2), chemokine (CXCL8), B-cell lymphoma protein (BCL2). Retinoid Acid Receptor (RARG) and Androgen Receptor (AR) sub network are bridging system of regulation in breast cancer molecular process. These results show that lauric acid may interact with many proteins by AR sub network to increase apoptosis and reduce cancer cell proliferation. These results show that lauric acid may interact with many proteins to increase apoptosis and reduce cancer cell proliferation.
Analysis of growth kinetics and colony-forming unit efficiency of human dental pulp stem cells cultured in different media and supplements
Authors: Chethan Kumar , Shetty Shishir , Kurkalli Basan Gowda , Shetty Veena , Mohana Kumar Basavarajappa
Published: August 2021

Dental tissues are considered as ideal autologous sources of multipotent stem cells. Presently, human dental pulp stem cells (DPSCs) are largely being isolated and expanded in media containing fetal bovine serum (FBS). However, the use of FBS has limitations due to its animal origin. Therefore, the present study evaluated the morphology, proliferation rate, population doubling time (PDT) and colony-forming unit fibroblast (CFU-F) efficiency of DPSCs cultured in animal serum-containing medium (SCM) and serumfree medium (SFM) in addition to serum-free culture conditions by supplementing human blood-derivatives such as platelet lysate (PL), fresh frozen plasma (FFP) and umbilical cord blood serum (UCS) at 2.5%, 5% and 7.5% concentrations. Established DPSCs had spindle-shape during primary culture but acquired characteristic fibroblast-like features when cultured in PL, FFP and UCS. DPSCs in SCM, SFM and PL had significantly (P<0.05) higher proliferative potential than those in UCS and FFP and these observations were supported by PDT values. The CFU efficiency of DPSCs was confirmed in all culture conditions with a slightly varied clonogenic potential in blood-derived components. Based on the growth kinetics and CFU ability, it is concluded that PL could be considered as a suitable alternative to FBS for the ex vivo expansion of DPSCs.
Plants as Potential Antimycobacterial Agents and their various Screening Methods
Authors: Revathy Kalyanasundaram , Jerrine Joseph , Wilson Aruni
Published: August 2021

Tuberculosis (TB) remains a threat to the human health worldwide. It causes mortality and morbidity in malnutrition and immunodeficient persons. It is an airborne infection which spreads from human to human through coughing and sneezing. The resistance development and the drug related toxicities associated with the current antitubercular treatment often necessitate the researchers to develop a new candidate for the treatment of tuberculosis. The selection of a feasible and reproducible method for the screening of new bioactive compounds in a high throughput method is necessary to find a hit from the list of compounds. Plants are the rich source of bioactive compounds and found their wide application globally for their medicinal properties since ancient times. The change of an era from antibiotics to phytomedicines certainly minimizes the difficulty of drug resistance and drug related toxicities. This review highlights the screening methods for the development of candidates against M. tuberculosis to understand the potential of various plant species reported to be active against various mycobacterial strains.
Biological Activities of Plant Polysaccharides, Mechanism of Action and Biomedical Applications
Authors: Govindarajan S. , Ayesha Noor
Published: August 2021

Bioactive constituents of plants have received great attention in recent times due to their many pharmacological and therapeutic properties. Plant polysaccharides are one of the constituents which are found abundantly in nature and are involved in cell-cell communication, immune recognition and eliciting defense mechanisms against infection of pathogens. Bioactive plant polysaccharides have an advantage of non-toxicity and have various functions such as antioxidant, antidiabetic, anti-inflammatory, anticoagulant, antibacterial and anticancer activities. The biological activity of plant polysaccharides depends on their sugar composition, molecular size, distribution of functional groups, extraction, treatment procedures and chemical modifications. The main goal of this review is focused on the sources of plant polysaccharides, their biological activities and their mechanism of action. Moreover, this review has also focused on biomedical and pharmaceutical applications such as drug delivery, wound healing and tissue engineering.
A CRIANÇA E A TECNOLOGIA DIGITAL: BRINCANDO E APRENDENDO CIÊNCIAS NA EDUCAÇÃO INFANTIL
Authors: Brito Dayane Wellén Silva , Andrade Alexandra Nascimento de , Lobo Huanderson Barroso
Published: August 2021

O presente artigo tem como objetivo refletir sobre as possíveis articulações das tecnologias digitais na educação, destacando, nesta pesquisa, as mesas educacionais chamadas Mundo das Descobertas ao desenvolvimento das ciências com/por e para as crianças, pois elas são sujeitas de direitos, dotadas de inteligência, emoções e sentimentos; capazes de observar, registrar informações, argumentar, debater, fazer escolhas e expressar-se em diferentes linguagens. A escolha das mesas educacionais Mundo da Descoberta se deu por fazer parte de um projeto da Secretaria Municipal de Educação (SEMED /Manaus) aos Centros Municipais de Educação Infantil (CMEIs). O destaque aos conhecimentos das ciências foi uma decisão, mediante a uma votação das crianças pelo jogo “No tempo dos dinossauros”. A investigação realizada perpassou por uma pesquisa de abordagem qualitativa, através de uma intervenção pedagógica organizada mediante a uma sequência didática. O presente estudo abordou temáticas sobre as tecnologias digitais na educação e práticas pedagógicas envolvendo vivências/experiências e brincadeiras sobre curiosidades científicas de Paleontologia na Educação Infantil (EI), oportunizando as crianças explorarem algumas curiosidades sobre os Dinossauros. A pesquisa foi realizada em um CMEI, localizado na zona leste de Manaus, com crianças do 1º período. As atividades realizadas nas Mesas Educacionais possibilitaram às crianças a aproximação das tecnologias digitais e uma aprendizagem mais satisfatória, acompanhada de um processo de práticas pedagógicas que buscou envolver a linguagem científica e tecnológica digital.
UTILIZAÇÃO DE METODOLOGIAS ATIVAS APOIADAS EM TECNOLOGIAS DIGITAIS PARA O ENSINO DE QUÍMICA: UM RELATO DE EXPERIÊNCIA
Authors: Field´s Karla Amâncio Pinto , Ribeiro Katia Dias Ferreira , Souza Raquel Aparecida
Published: August 2021

O objetivo deste trabalho é apresentar os resultados de uma experiência desenvolvida no componente curricular Química aplicada a serviços de alimentação, do curso Superior de Tecnologia em Gastronomia do Instituto Federal de Brasília - campus Riacho Fundo, na qual foram utilizadas metodologias ativas apoiadas em tecnologias digitais. Escolhemos o relato de experiência para apresentar, discutir e analisar a vivência de uma professora, também autora deste trabalho, que pautou seu planejamento de aulas remotas em um curso de extensão. Os dados foram organizados em cinco experiências com metodologias ativas, a saber: storytelling; storytelling e resolução de problemas; ensino híbrido/sala de aula invertida; aprendizagem em pares; e aprendizagem maker. Os resultados dessa experiência apontam ter havido uma apropriação metodológica por parte da professora, o que é exemplificado pelo planejamento dos roteiros de aprendizagem, conforme proposto a partir das metodologias ativas experienciadas.
DESENVOLVIMENTO DE UMA SEQUÊNCIA DIDÁTICA INVESTIGATIVA SOBRE EDUCAÇÃO AMBIENTAL NA EDUCAÇÃO DE JOVENS E ADULTOS EM PONTES E LACERDA-MT
Authors: Cardoso Adriele Silva , Pedrotti-Mansilla Débora Eriléia
Published: August 2021

O presente estudo tem como objetivo analisar as contribuições da utilização de uma sequência didática investigativa na aprendizagem sobre Educação Ambiental no Ensino de Jovens e Adultos. O local da pesquisa foi o Centro de Educação de Jovens e Adultos 6 de Agosto, no município de Pontes e Lacerda-MT. A Educação Ambiental pode ser trabalhada em qualquer um dos componentes curriculares e não somente nos de Biologia, de Ciências Naturais ou de Geografia. A Educação de Jovens e Adultos veio para suprir o direito à educação de muitos cidadãos que, por diversos motivos, não conseguiram estudar quando mais novos. O ensino investigativo traz uma nova roupagem na metodologia de ensino porque o estudante é instigado a buscar respostas, fazendo, assim, que se interesse no conteúdo apresentado. Em uma sequência didática, o conteúdo segue uma ordem de atividades, que podem ser elaboradas conforme a complexidade do assunto em horas/aulas, sendo uma ótima opção para uso dos professores. A pesquisa teve abordagem qualitativa, com a perspectiva da pesquisa-ação-participativa. A participação dos estudantes em todo o processo da sequência didática foi muito significativa e com certeza levarão esses conhecimentos aos seus familiares e amigos. Ao final da aplicação, observamos que o desenvolvimento da sequência didática adequada à modalidade de jovens e adultos, com seus espaços de tempo diferenciados, propiciou condições para o estudo da Educação Ambiental de forma a garantir um vasto aprendizado aos estudantes.
Effect of solvent types on the antioxidant activity and total flavonoids of some Bangladeshi legumes
Authors: Hossain M.A. , Arafat M.Y. , Alam M. , Hossain M.M.
Published: August 2021

In this study, an attempt was made to estimate the antioxidant activity of some popular
Bangladeshi legumes by employing DPPH radical scavenging assay, total phenolic
content (TPC), and ferric reducing antioxidant assay (FRAP). The extraction efficiency
and total flavonoid content (TFC) of hyacinth bean (Lablab niger), kidney bean
(Phaseolus vulgaris), black gram (Vigna radiate), mung bean (Vigna mungo), and green
pea (Pisum sativam) by different solvents were also examined. Extraction was done using
80% acetone, ethanol, and methanol as solvent. The maximum and minimum DPPH
scavenging activity was shown by mung bean (27.67±1.53%) and Hyacinth bean
(4.33±1.53%), respectively using ethanol as solvent. The highest and lowest FRAP value
was recorded 89.60±0.80 μg AAE/mL for green pea and 35.11±1.39 μg AAE/mL for
mung bean, respectively with ethanol solvent. For TPC, green pea with ethanol solvent
showed the highest value (1045.92±21.30 mg GAE/100 g), and mung bean with ethanol
solvent exhibited the lowest value (415.92±1.44 mg GAE/100 g). For TFC, black gram
with ethanol solvent exhibited the highest value (342.21±3.05 mg QE/100 g), while mung
bean with acetone solvent exhibited the lowest value (77.38±0.80 mg QE/100 g).
The effect of hydrolyzate on amino acid levels in Nile tilapia (Oreochromis
niloticus)
Authors: Nuryanto  , Chasanah E. , Afifah D.N. , Sulchan M. , Martosuyono P. , Ilhsani K.
Published: August 2021

Fish is one of the most important foods in the human diet because of its high nutritional
quality. One of the potential local foodstuffs in Grobogan is Nile tilapia (Oreochromis
niloticus). Nile tilapia has a high nutrient content, especially protein. To obtain better
benefits from fish protein, it can be processed into fish protein hydrolysate (FPH)
products. Fish protein hydrolysates (FPH) which contain a mixture of small protein or
peptides and free amino acids are beneficial for children diet, in preventing and combating
malnutrition problems through readily absorbed essential amino acids. This study aimed to
analyze the amino acid profile of Nile tilapia and fish protein hydrolysate (FPH) from Nile
tilapia. The treatments included processing Nile tilapia into hydrolysate and analyse amino
acids of Nile tilapia before and after hydrolysate. The process of making FPH uses a local
microbial protease enzyme from Bacillus licheniformis. Amino acids composition was
analysed using an internal method developed by Saraswanti Indo Genetech laboratory (18-
5-17/MU/SMM-SIG, UPLC). Data were analysed using the paired t-test statistical test.
The results showed there were significant differences in the rate of all amino acid profiles
(p<0.05), except L-Aspartic Acid, L-Tyrosine and L-Histidine (p>0.05). From the
research, it can be concluded hydrolysate processing has an effect on the increase of Lglutamic acid and L-lysine amino acid.
ECOFEMINISMO: ANÁLISE DA MULHER COMO VETOR DE SUSTENTABILIDADE
Authors: Paz Flávia Piccinin , GUBERT MARCELO WORDELL
Published: August 2021

O artigo visa o estudo do empoderamento da mulher, na finalidade de que através do conhecimento da sua relação com o ambiente estas venham a desenvolver atividades de sustentabilidade. Com subsídio teórico em Ulrich Beck, e artigos científicos, através do método dedutivo, analisou o ecofeminismo, sua origem e correntes, propondo uma compreensão do princípio da precaução e da teoria do risco. Através do método hipotético-dedutivo, focalizou na análise do empoderamento da mulher como vetor de sustentabilidade. Concluiu que a mulher é meio natural de sustentabilidade, sendo real aplicação do princípio da precaução, agindo como meio de prevenção ao dano ambiental.
MULHERES NEGRAS E SUAS TRAJETÓRIAS EM BUSCA DA REPRESENTATIVIDADE
Authors: Duarte Marcela , Gonçalves Alves Stephani Renata
Published: August 2021

Este artigo debate a questão de gênero e raça, abordando a feminilidade e a negritude. O percurso adotado parte do contexto histórico, trazendo elementos que dão conta de explicar como construiu-se a imagem da mulher negra até hoje e seus estigmas. A invisibilidade frente a publicidade se faz importante para demonstrar que ainda que haja uma grande parcela de mulheres negras, elas encontram obstáculos em se ver contempladas pelas mídias. As garantias legais da não discriminação de gênero e raça somam a este trabalho demonstrando que legalmente já existem dispositivos que asseguram a igualdade, porém não alcançam a realidade.
O PODER JUDICIÁRIO NA ADMINISTRAÇÃO DE CONFLITOS FAMILIARES: IMPOSIÇÃO OU COMPOSIÇÃO?
Authors: THISEN GRACIELA FERNANDES , SPENGLER FABIANA MARION
Published: August 2021

A pesquisa analisará o Poder Judiciário que tradicionalmente lida com a litigiosidade frente aos mecanismos de solução de conflitos, em especial a mediação. Com isso, foi possível verificar se a mediação familiar aplicada no decorrer do processo judicial conseguiu romper ou não com o modelo tradicional, dogmático, normativo e formalista do Poder Judiciário ou, não passará de mais uma etapa processual. O método de abordagem da pesquisa será o dedutivo. Como método procedimental será utilizado o monográfico. Concluiu-se que, para que haja uma resposta efetiva às demandas sociais é necessário que haja a jurisconstrução, quebrando o paradigma tradicional.
ANÁLISE PRINCIPIOLÓGICA DA MEDIAÇÃO COMUNITÁRIA NA PERSPECTIVA DO PLURALISMO JURÍDICO
Authors: Lothammer Carlos Graziela Regina Munari , Vieira Rodrigues Sheila Rosane , Wolkmer Antonio Carlos
Published: August 2021

O problema do presente artigo consiste na análise dos princípios norteadores da Mediação Comunitária na perspectiva do Pluralismo Jurídico. Assim, o objetivo geral é identificar as corretas interpretações de cada princípio, apontando os que são essenciais e que dão suporte a Mediação Comunitária, permitindo que a prática do método seja efetivo. O presente estudo compreende dois momentos: no primeiro, abordou-se a Mediação Comunitária e seus aspectos conceituais e, em um segundo momento, buscou-se realizar uma análise principiológica. O método de abordagem utilizado foi o dedutivo, com a técnica de pesquisa bibliográfica.
CONSTITUCIONALIDADE DOS MEIOS DE EXPROPRIAÇÃO EXTRAJUDICIAL DA PROPRIEDADE DE BENS IMÓVEIS. POSSÍVEL ARBITRABILIDADE DO TEMA
Authors: Cunha Ricardo Henrique Alvarenga , Correia Rodrigo Rodrigues , Machado Lorruane Matuszewski
Published: August 2021

O objetivo deste trabalho é investigar a possibilidade de ampliação das opções de execução extrajudicial de bens imóveis no direito brasileiro, especialmente com o uso da arbitragem. O trabalho apresenta como resultado uma reflexão sobre a constitucionalidade da incorporação da expropriação extrajudicial de imóveis pelo juízo arbitral, tendo por objetivo contribuir para a desjudicialização de processos executórios em nosso ordenamento. Quanto ao método de investigação, o trabalho adotará os métodos dedutivo e hipotético dedutivo, cujo estudo será constituído a partir de pesquisa bibliográfica, de levantamento legislativo e jurisprudencial. A investigação bibliográfica se processará em livros e revistas sobre o tema.
RELEITURA DO PRINCÍPIO DA CAPACIDADE CONTRIBUTIVA SOB A PERSPECTIVA DO DIREITO TRIBUTÁRIO AMBIENTAL
Authors: Martins Joana D'Arc Dias
Published: August 2021

O artigo objetiva analisar o princípio da capacidade contributiva sob a ótica da tributação ambiental. Busca-se demonstrar que tratar a tributação ambiental com os mesmos critérios tradicionais destituiria esse instrumento de seu papel orientador e estimulador de condutas, bem como da possibilidade de utilizá-lo como mecanismo de proteção ambiental, razão pela qual esta pesquisa tem como escopo evidenciar que, havendo respeito ao mínimo existencial e ao não confisco, além de outros direitos fundamentais, o princípio pode ser mitigado, desde que passe pelo teste da idoneidade, proporcionalidade e adequação. Nesse estudo será utilizado o método dedutivo e a pesquisa bibliográfica.
A SUSTENTABILIDADE SOCIAL COMO PARÂMETRO DE SOLUÇÃO DE CONFLITOS ENTRE DIREITOS NAS CIDADES
Authors: Provin Alan Felipe
Published: August 2021

O presente estudo tem como objetivo evidenciar a sustentabilidade social como parâmetro de solução de conflitos entre direitos fundamentais nas cidades, em busca de um ideal sustentável, minimizando as desigualdades. Considerando que as cidades são aglutinadoras de conflitos, e os métodos tradicionais de solução de conflitos ignoram o lado social dos direitos, justifica-se a presente pesquisa pela possibilidade de contribuição aos estudos de solução de impasses fundamentais sob um novo olhar: o da sustentabilidade social. Concluiu-se pela possibilidade de aplicação desse instituto, em conjunto com o arcabouço normativo existente, fazendo-se uso de pesquisa bibliográfica e método indutivo.