bluuebunny/crossref_metadata_2025 huggingface dataset:
IDENTIFIKASI KRITERIA PRASYARAT GREEN BUILDING PADA GEDUNG LABORATORIUM TERPADU PENDUKUNG BLOK MASELA
Authors: Tehuayo Susiana Aprilia , Buyang Chirsty Gery , Sangadji Fauzan A
Published: November 2023

Abstrak

Permasalahan lingkungan khususnya pemanasan global menjadi topik permasalahan yang mencuat akhir-akhir ini. Oleh karena itu perlu adanya pembangunan dengan berkonsep green building yang dapat mengurangi atau menghilangkan dampak negatif terhadap lingkungan, dengan menggunakan lebih sedikit air, energi atau sumber daya alam, serta memiliki dampak positif terhadap lingkungan dengan menghasilkan energi sendiri. Pada gedung Laboratorium Terpadu Pendukung Blok Masela Universitas Pattimura Ambon dirancang dengan menggunakan konsep green building sehingga perlu adanya identifikasi secara menyeluruh untuk memaksimalkan persentase penerapannya. Tujuan dari penelitian ini untuk mengidentifikasi apakah gedung Laboratorium Terpadu Pendukung Blok Masela Universitas Pattimura Ambon sesuai dengan kriteria prasyarat yang ditentukan GBCI. Metode yang digunakan dalam penelitian ini adalah analisis deskriptif yang didapat melalui pengumpulan data primer dan sekunder. Data primer berupa observasi lapangan, pengukuran dan wawancara, serta melakukan analisis data dengan menggunakan chek list, sementara data sekunder berupa pengumpulan data site plan beserta data-data lain yang tidak ditemukan pada pengambilan data primer. Setelah dilakukan penelitian, hasil akhir menunjukan bahwa gedung Laboratorium Terpadu Pendukung Blok Masela Universitas Pattimura Ambon memenuhi 6 (enam) prasyarat kelayakan bagunan diantaranya, tersedia luasan gedung sebesar 12.200 m2, adanya kepemilikan rencana UKL/UPL, fungsi gedung sesuai dengan peruntukan lahan berdasarkan RT/RW setempat, kesesuaian gedung sesuai dengan standar keselamatan untuk kebakaran, kesesuaian gedung sesuai dengan standar aksesibilitas difabel dan kesesuaian gedung sesuai standarisasi bangunan tahan gempa.

 

 

Kata kunci: Pemanasan global, green building, Laboratorium Terpadu.
PERENCANAAN FASILITAS PELABUHAN KAMARIAN UNTUK MENUNJANG PELAYARAN RAKYAT ANTAR-PULAU DI PROVINSI MALUKU
Authors: Kakerisa Izak R , Berhitu Pieter Th , Mandaku Hanok
Published: November 2023

Pengembangan Pelabuhan Kamarian di Provinsi Maluku sangat penting guna menunjang eksistensi pelayaran rakyat antar-pulau. Namun, pengembangannya membutuhkan investasi dan dukungan informasi tentang arahan pengembangan dan kapasitas setiap fasilitas agar sesuai dengan kebutuhan. Oleh sebab itu, perencanaan yang komprehensif sangat penting dilakukan. Penelitian ini bertujuan untuk menganalisis tingkat pertumbuhan muatan dan kebutuhan fasilitas serta mendesain lay-out Pelabuhan Kamarian. Metode yang digunakan adalah regresi linear untuk peramalan pertumbuhan muatan, standart pelayanan pelabuhan untuk analisis kebutuhan fasilitas dan activity relationship chart (ARC) untuk mendesain tata letak pelabuhan. Hasil penelitian memperlihatkan bahwa untuk 5 tahun mendatang tingkat pertumbuhan muatan mencapai 5,5%/tahun untuk penumpang, 1,2%/tahun untuk kendaraan R-2 dan 1,3%/tahun untuk barang. Berdasarkan data tersebut, dengan beroperasinya 2 unit kapal, maka diperkirakan pada tahun 2026 masing-masing kapal akan mengangkut 47 orang penumpang pergi (LF = 1,56), 38 orang penumpang datang (LF = 1,26), 1 unit motor (LF = 0,33), dan 3,8 ton barang (LF = 7,59). Kondisi tersebut membutuhkan adanya fasilitas dermaga berukuran 32,5 x 1,5 meter; gedung terminal seluas 206 m2; dan areal parkir seluas 96,0 m2. Sedangkan lay-out pelabuhan didesain dengan pendekatan activity relationship chart. Pengembangan Pelabuhan Kamarian diharapkan dapat menunjang pelayaran rakyat antar-pulau di Provinsi Maluku.
Knowledge, Attitudes, and Practices on Ethics in Biomedical Animal Research in Mexico
Authors: Heredia-Antúnez Anayántzin , Galarde-López Miguela , Téllez-Ballesteros Elizabetha , Vanda-Cantón Beatriz
Published: November 2023

The most widely accepted ethical concept for the mitigation of harm to animals used in biomedical research is known as the 3Rs, which refer to replacement, reduction, and refinement. The aim of our study was to determine the ethical and regulatory criteria that researchers in Mexico
consider when developing their animal research protocols and that members of the ethics committees use when they evaluate and approve these protocols. We circulated a survey to 300 individuals from different research institutions and received responses from 179 researchers and members of ethics
committees on questions related to their knowledge, attitudes, and practices toward the use of animals in research based on the 3Rs. The responses obtained indicate that the respondents were aware of the 3R concept, and they claim to apply these principles. However, the responses revealed
resistance to using alternatives for research, testing, and teaching (66%). Nineteen percent of the researchers reported that their institutions do not have an integrated Institutional Animal Care and Use Committee (IACUC). Around 80% of respondents were aware of Mexican regulations. The knowledge
and application of the 3Rs by researchers and members of the IACUC is a fundamental concept in animal research. Such knowledge contributes the use of ethical standards, attitudes, and practices relevant to the use of animals in research.
Fruchtlose Suche nach einem Common Ground?
Authors: Crepaldi Gianluca
Published: November 2023

Der Beitrag rekapituliert die wiederkehrende Debatte um Vielheit und/oder Einheit in der Psychoanalyse, die als fruchtlos kritisiert wird, weil sie keine nennenswerten Ergebnisse liefern konnte und die psychoanalytische Gemeinschaft von innen schwächt. Anstelle einer Fortsetzung der Suche nach dem Common Ground, argumentiert der Autor für die Akzeptanz irreduzibler Pluralität in der Psychoanalyse des 21. Jahrhunderts, welche anhand der Ausdifferenzierung der postfreudianischen Triebtheorien exemplarisch dargestellt wird. Auswege aus lähmenden Pluralismus-Diskussionen findet der Autor in einer die psychoanalytische Pluralität begleitenden, »konnektionistischen« Konzeptforschung, die einen festen Platz im psychoanalytischen Diskurs einnehmen soll. Konzeptforschung hat zudem hohe praktische Relevanz, da die Ausbildung konzeptueller Kompetenz unerlässlich für eine erfolgreiche Anwendung der Psychoanalyse in unterschiedlichen Handlungsfeldern ist.
Perspektiven einer systemischen Sonderpädagogik psychodynamischer Prägung
Authors: Willmann Marc
Published: November 2023

Psychodynamisches und systemisches Denken sind in der Pädagogik und Sonderpädagogik etabliert. Woran es in der fachwissenschaftlichen Rezeption indes mangelt, ist eine Zusammenführung und Integration der Theorieperspektiven. Ein solcher Versuch wird in den vorliegenden Ausführungen unternommen. Vor dem Hintergrund des Modells multiperspektivischer Fallarbeit in der Sonderpädagogik wird das fruchtbare Ergänzungsverhältnis verdeutlicht, in dem zwei Differenzlinien (Systemebene versus Innen/Außen-Differenz) betrachtet werden. Im Ergebnis wird für einen eklektischen Standpunkt in der (Sonder-)Pädagogik plädiert, von dem aus sich Systemtheorie und Psychoanalyse als relevante Referenztheorien für die Erziehung und Bildung erweisen.
Las aptitudes del embrión. Propuestas neoplatónicas del tratado Ad Gaurum
Authors: Zamora Calvo José María
Published: November 2023

Para explicar de qué modo el embrión recibe el alma, el autor del tratado epistolar Ad Gaurum, probablemente Porfirio, aplica a la noción de “aptitud” (ἐπιτηδειότης) un nuevo enfoque que, desde la metafísica neoplatónica, redefine la noción aristotélica de “en potencia”. En el momento del parto, se implanta en el embrión que es apto para recibirla un alma animal, que le dota de sensación e impulso y que le permite un movimiento local.
Method of planning data processing tasks in distributed systems with limited information about available resources
Authors: Kozyriev Andrii , Shubin Ihor
Published: November 2023

In today's digital landscape, distributed data processing systems (DDPs) are becoming increasingly critical to efficiently process, analyze, and manage large volumes of data. These systems are often used in commercial, scientific and social domains to process complex data in real-time or batch mode. One of the key components of such systems is task scheduling, which is an extremely complex process, particularly when information about resource requirements is not complete or accurate. The subject of research are algorithms, methods and approaches used for scheduling tasks between nodes in distributed systems. The purpose of the study is to create an optimized method of task planning in the RSOD with limited availability of information about available resources. The task of the research: to analyze the limitations of modern methods for scheduling tasks in distributed data processing systems (DDS); optimize the method of scheduling tasks based on metadata between RSOD nodes, based on the methodology of searching for nearest neighbors using the method of localized hashing and the algebra of finite predicates; develop the architecture of the software solution and its implementation based on the optimized method; test the algorithm on the example of a video decoding task. The following methods were used: statistical algorithms and techniques such as classification and cluster analysis were used to predict resource requirements, and visualization techniques assisted in the analysis and interpretation of results. As a result of the work: the limitations of modern methods for the distribution of tasks in distributed data processing systems (DDPs) were analyzed; an optimized method of task planning based on metadata in RSOD was created, based on the methodology of searching for nearest neighbors using the method of localized hashing and the algebra of finite predicates; the processes in the modified nearest neighbor search algorithm are detailed; the architecture of the software solution was developed, which integrates an optimized method of task planning based on metadata and resource allocation; validation of the software solution was carried out with the help of a practical scenario – the use of the created algorithm in the planning task for decoding video information. The conclusions of this study confirmed that the proposed method, based on the methodology of localized hashing and the use of finite redicate algebra, is effective even with insufficient or limited information about resource needs. This highlights the possibility of using dynamic scheduling strategies to adapt to changing load conditions and resource availability.
Methods of automation and interpretation of the quality educational tests in distributed virtual learning systems
Authors: Shubin Ihor , Liashyk Volodymyr
Published: November 2023

The subject matter of the article is the development of mathematical and algorithmic support for intellectual tools, which allows you to conduct continuous control of the knowledge of students (subjects of study) objectively and comprehensively. The goal of the work is to create methods for assessing the quality of educational tests and automating such processes. The following tasks were solved in the article: formation of a testing model in a distributed virtual learning environment and a validity assessment model based on the content of sets of test tasks. The following methods used are – algebra of finite predicates and operations, methods of mathematical statistics and methods of intellectual data analysis. The following results were obtained – the principles of intellectual analysis of the value of reliability coefficients, validity coefficients, discriminability coefficient, the difficulty index of the task of assessing the knowledge of subjects of training are formulated. Conclusions: the application of methods of formalization of test evaluation, analysis of software requirements, software development confirm the need to introduce quantitative methods of assessing students' knowledge into educational practice. The introduction of quantitative methods involves the correct setting of control goals, the selection of the measurement object and the selection of measurement tools. The use of pedagogical tests contributes to the effective implementation of all control functions and corresponds to its main principles for solving the problem of assessing the quality of tests, based on distributed virtual learning models and analysis methods. A test example of calculations was developed, with the help of which the efficiency of the proposed methods was researched.
Steganographic method of acoustic information protection in critical applications systems
Authors: Mozhaiev Oleksandr , Gnusov Yurii , Manzhai Oleksandr , Strukov Volodymyr , Nosov Vitalii , Radchenko Valery , Yenhalychev Serhii
Published: November 2023

The subject of the study is the process of protecting acoustic information in critical computer systems to ensure the required level of system security. The purpose of the article is to study the method of protecting acoustic information in critical computer systems by means of masking to ensure the impossibility of unauthorized access to the system. The paper outlines the following tasks: to analyze the software and hardware masking of speech; to study the masking of speech messages in order to introduce unrecognizability; to consider the features of speech message compression; to investigate methods of covert transmission of acoustic information. The results of the work, which were obtained using mathematical methods of information transformation in computer systems, are potentially possible methods of masking speech messages to ensure the impossibility of unauthorized access to the system. The analysis of the functioning of the proposed methods made it possible to formulate specific conclusions. The research has shown that the use of direct expansion of the spectrum of discrete signals for steganographic purposes helps to covertly embed information messages in still images. The task of extracting a message on the receiving side of a steganography system is equivalent to the task of detecting information from a mixture of a useful signal and an interference in a broadband communication system.  The research revealed certain disadvantages of steganographic systems with an expanded spectrum of discrete signals: the probability of correct extraction of embedded data depends on the amount of distortion introduced, which depends on the provided bandwidth of the steganographic channel. Further research is desirable to analyze the possible use of methods for synthesizing large ensembles of quasi-orthogonal discrete signals with improved ensemble, structural, and correlation properties to ensure higher security of acoustic channels in computer systems for critical applications.
Model of elemental data flow distribution in the internet of things supporting fog platform
Authors: Rezanov Bohdan , Kuchuk Heorhii
Published: November 2023

The subject of the research is models and methods for optimizing resource and task management in the fog computing environment of the Internet of Things (IoT). The increasing number of connected devices and the volumes of data collected in IoT networks make it essential to improve management systems that ensure the optimal distribution of tasks and resources. Fog computing addresses this challenge by distributing computational tasks closer to data sources and end-users. The goal of this work is to enhance the efficiency of fog computing technologies to achieve optimal task and resource allocation in IoT networks. The main tasks of this work are as follows. Firstly, considering the diverse requirements of computational resources and tasks in IoT, reviewing existing methods and developments in the field is necessary. Secondly, it is essential to investigate and compare clustering methods, particularly DBSCAN and C-Means, for effective resource management. The DBSCAN clustering method enables efficient task distribution based on their location, while the C-Means method allows grouping resources based on their characteristics. The final task involves developing a mathematical model that considers input parameters such as system response, cluster resource requirements, data proximity to processing, etc. This model will enable the analysis of potential scenarios and decision-making regarding the optimal distribution of tasks and resources in the IoT environment. Conclusion. This research aims to solve the urgent problem of managing resources and tasks in the fog IoT environment. A review of existing methods and developments in resource and task management in IoT is conducted. DBSCAN and C-Means clustering methods are compared to determine their effectiveness in resource management. A set-theoretic model is developed that considers various parameters for making optimal decisions on the distribution of tasks and resources. It is established that the use of clustering methods and the developed model help to improve system performance and ensure more efficient use of fog computing resources in the IoT environment.
A model for forecasting the volume of the entertainment services market under non-determinative conditions
Authors: Dovgopol Nina , Peresada Olena , Pribylnova Inna
Published: November 2023

The subject matter of the article is the theoretical-methodical and applied principles of modelling and forecasting indicators of the market volume of entertainment services. The goal of the work is to find a mechanism that will allow determining the volume of subscribers, taking into account exogenous variables, especially during socially unstable situations, such as a pandemic, war, cataclysms, etc. The following tasks are solved in the article: formation of criteria for companies for which the created mechanism is planned to be applied; review of basic autoregression models; determination of factors that should serve as an external influence when predicting the number of subscribers; creation of a multi-criteria choice problem; conducting experiments according to the proposed methodology to test the proposed hypotheses and systematize the obtained results. The following methods are used: analytical and inductive methods for forming factors of external influence and description of target companies; expert evaluation method for determining the most influential external indicators; experimental method, statistical methods of processing time series and methods of multi-criteria evaluation to determine the most effective autoregression model. The following results were obtained: the factors of external influence were formed: As external variables, it was decided to choose: the dynamics of the incidence of coronavirus, the rate of change in the global gross domestic product, the change in the S&P500 index, and the news from the world's largest news agencies converted into numerical form; a set of criteria for comparing models was created, saving forecasting time, accuracy, the possibility of taking into account external influence and the specificity of taking it into account; it was determined that the most accurate model is autoregression of the moving average, which at the same time is the most effective model given the created problem of multi-criteria selection; the similarity of the obtained results of experiments with global and domestic research is established. Conclusions: the use of analytical and inductive methods in combination with an experimental approach made it possible to obtain an effective (with an accuracy of more than 95%) mechanism for forecasting the market volume of companies that operate in the film industry and have a signature pricing model. The obtained result will allow players with a smaller market volume not to lose their audience due to the instability of the external environment, and, accordingly, will stimulate the development of the industry in general.
The conceptual model of digital historical quantorium: Methods of designing the additional educational environment for teaching History
Authors: Belyaev Dmitriy Anatolevich , Frolova Nataliya Alekseevna , Terletskiy Aleksey Sergeevich
Published: November 2023

The aim of the research is to model the architecture of the educational environment of the digital historical quantorium. Based on the dynamics of the emergence and the experience of profiling quantoriums, the article identifies their characteristic subject specialization. The possibility of creating a historical quantorium as a special educational space relevant to modern technoculture is considered. The scientific novelty of the work lies in identifying three educational clusters of the digital historical quantorium – video gaming, virtual reality, and augmented reality. Specific screen-digital educational activities are also modelled and serve as forms of teaching various aspects of History. The research resulted in the formation of a conceptual technological understanding of the possible clusters of the digital historical quantorium. Besides, a methodological toolkit for working in this educational environment was outlined, which can complement and update modern practices and approaches to the study of History.
Linguistic representation of the features of national mentality in a comparative aspect (Russian-German parallels)
Authors: Bojkova Irina Borissovna
Published: November 2023

The aim of the research is to investigate whether the lexicon of the Russian language reflects a national trait, as perceived by Europeans, of a natural inclination of Russians towards subordination. The paper conducts a comparative lexico-semantic analysis of the main expressions denoting the situation of subordination in Russian and German. The analysis aims to identify similarities and differences in semantic features, as well as the denotative potential of the selected lexemes. The results show that the idea of subordination is more deeply ingrained in the semantics of German lexemes than in that of Russian lexemes. The interpretation of the comparative results draws on the principles of linguoculturology, imagology and the contemporary theory of archetypes. Taking these principles into account leads to the preliminary conclusion that the common European opinion about the natural inclination of Russians towards subordination is a false stereotype. The research is novel in that it is the first to examine from a comparative perspective the linguistic representation of a national stereotype that reflects the perception of a nation from an external perspective rather than self-perception. The work is the first to provide evidence that linguistic data does not correspond to the stereotype. Scientific novelty lies also in the fact that the proposed approach expands the scope of research in linguoculturology, which has traditionally focused on the linguistic representation of cultural concepts rather than national mentality.
A Re-evaluation and Analysis of CPJ V 638 and Its Implications for Understanding Social Relationships in the Roman Empire, and the Roman-Jewish Relationship in Particular
Authors: Olshanetsky Haggai
Published: November 2023

The ostracon O.Ka.La. Inv. 228, recently added to the CPJ, received little attention, even though this ostracon may offer unique perspectives on social relationships in Roman-Egypt, particularly Roman-Jewish ones. In the ostracon, the Jews’ bread rations had to be replaced with wheat, possibly due to Passover. The current article shows that there are two other options, although only one is equally as probable as the Passover one. This other option emphasizes unique procedures implemented by the Roman army to allow Jews to keep their religious practices. It also raises the possibility that the bread stamps used by the Roman army to prevent theft also enabled minorities to easily serve while keeping their religious practices. The article stresses the importance of this ostracon and the implications it has on our understanding of Roman-Jewish relationships and the Roman attitude towards minorities, in general, throughout the Principate.
Multifocality as an adverse histopathological factor in papillary thyroid carcinoma
Authors: Dinets A. , Gorobeiko M. , Pysmenna Y. , Lovin A. , Abdalla K. , Hoperia V.
Published: November 2023

Papillary thyroid carcinoma (PTC) is characterized by various clinical and pathomorphological features, such as metastases to the locoregional lymph nodes and radioiodine resistance. It could also be diagnosed as a microcarcinoma coexisting with other benign thyroid pathologies or as multifocal growth. Of these, multifocality in PTC is considered an unfavourable pathomorphological feature. However, the research findings are controversial.
Objective — to investigate and evaluate the clinical and pathohistological features of multifocal PTC (mPTC) in comparison with unifocal (single nodule) PTC.
Materials and methods. Among the patients who underwent operative treatment at the clinical bases of the Department of Surgery, Institute of Biology, and Medicine at Taras Shevchenko National University of Kyiv, 91 were diagnosed with PTC and were included in the study.
Results. Out of the 91 patients, 31 (34%) had mPTC and 60 (66%) had PTC. Bilateral mPTC was diagnosed in 23 (74%) patients, which is in line with other studies. It is also worth mentioning, that 5 (16%) patients were diagnosed with multifocal growth only at the stage of histopathology section, without preoperative or intraoperative evidence of multifocality. A significantly higher frequency of locoregional metastasis was found in the mPTC group in 17 (55%) patients as compared to 18 (30%) patients with PTC (p=0.025). Lateral neck dissection was performed in 13 (42%) patients with mPTC, and in 13 (22%) patients with PTC (р=0.0525). Frozen section pathology was performed in 17 (24 patients with mPTC, and in 4 (10%) patients with PTC (р >0,05).
Conclusions. A higher frequency of locoregional metastasis and a higher propensity for performing a lateral neck dissection are both indicators of a higher biological aggressiveness of the carcinoma in PTC multifocal growth.
Optimisation of the blood supply at the flap donor site through the application of cutaneous negative pressure
Authors: Badiul P. O. , Sliesarenko S. V. , Rudenko O. I.
Published: November 2023

At present, perforator flaps are a very popular technique in reconstructive surgery. However, in spite of the fact that perforator flaps provide favourable aesthetic results, their use is often related to complications in the form of transplanted tissue perfusion disorders.
Objective —  to investigate the possibility of optimising the blood supply at the flap donor site through the application of cutaneous negative pressure (NP).
Materials and methods. The study was carried out from 2019 to 2021. A single‑arm clinical trial consisted of 20 individuals who presented with deep wound defects requiring flap coverage. A dynamic thermography study was conducted to examine the chosen donor site before and after dressing with NP.
Results. The temperature measurements obtained from the two selected warm perforator points and the point in the cool area between perforators prior to the application of NP showed a steady downward trend in temperature. Specifically, the temperature in the cool area was observed to be lower by an average of –1.89 °С and –2.12 °С as compared to warm points. The application of local NP had an impact on trend analysis of skin temperature, which demonstrated a significant decrease in the differences between values seen in the cool and warm areas. This effect was already noted after the first day of the NP system application, as evidenced by the everyday data collection. The «levelling» of temperature curves was associated with temperature rises both in the cool area and at the perforator exit points.
Conclusions. The findings obtained from thermography analysis suggest that the application of NP has the potential to enhance blood circulation in the intended donor area. Therefore, it is plausible to discuss the possibility of improved microcirculation in the skin and the beneficial effect of local cutaneous NP application on the state of anastomoses between perforators.
The Effectiveness of Applying Professional Competencies of Senior Age Group Specialists in the Transition to Industry 4.0
Authors: Mashina Ekaterina , Orlova Lyubov
Published: November 2023

The article is devoted to discussing the issues of improving the efficiency of using senior age group specialists’ competencies in the conditions of innovative economic development while transiting to Industry 4.0. The paper analyses the causes of senior age group workers’ vulnerability conditions associated with the subjective characteristics of their age group and leading to various manifestations of age discrimination in the open labour market. One of the main causes for such vulnerability is a deliberately underestimated assessment of their own competencies, which forces senior age group specialists to accept job invitations that do not correspond to their qualifications. The reasons for the systematic underestimation of their self-esteem are the constant feeling of external pressure from younger colleagues and management, as well as the inability to conduct an independent objective assessment of their own position in the labour market. Based on analysing foreign experience of successful integration of senior age group specialists’ competencies into the innovative economy, the paper states the proposals for forming a comprehensive solution to such a problem, taking into account the domestic labour market realities. At the same time, one of the necessary areas of work is creating information solutions that allow specialists to correctly assess their position in the labour market, one of which, built by the authors and based on the precedent analysis, is described in sufficient detail in the work.
Approaches to Enterprise Information Infrastructure Management Based on Integrating Quality Models and Software Design
Authors: Mikityuk Tatyana , Kocyuba Igor'
Published: November 2023

The article discusses approaches to forming and managing the enterprise’s information infrastructure. The choice of approaches to the information infrastructure formation and management should be based on a comprehensive analysis of the organization’s needs, its goals and resources, and should be adapted to the organization’s specific conditions and requirements. It is noted that the successful management of an enterprise’s information infrastructure doesn’t only require the right approach, but also competence and experience in the field of IT management. Regardless of the chosen approach, the efficiency of the infrastructure depends on using modern technologies and management methods, as well as taking into account the specifics of the company’s activities. To ensure the management process effectiveness, it is necessary to apply modern tools and methods, such as management process automation, data monitoring and analysis, risk management and information security. The article discusses various approaches to managing the enterprise’s information infrastructure, such as the ITIL standard, COBIT and SWEBOK. It is stated that an effective solution for enterprises is an individual approach that allows considering various quality models and KPIs. The importance of using modern technologies and methods of information infrastructure management to improve the efficiency of business processes, to ensure information security and confidentiality, as well as to reduce the cost of its processing and storage is emphasized.
TECNOLOGIAS DIGITAIS DE ENSINO-APRENDIZAGEM PARA EQUIPES DE SAÚDE SOBRE DELIRIUM EM IDOSOS HOSPITALIZADOS: REVISÃO INTEGRATIVA
Authors: Tamanini Dorigon Alícia , Amaral Longhi Fabiana , Aroni Patricia , Fernanda Carvalho Barreto Maynara , Wanderley de Barros Silva Maria Eduarda , Fernandez Lourenço Haddad Maria do Carmo
Published: November 2023

Objetivo: Identificar as evidências científicas disponíveis na literatura sobre as tecnologias digitais de ensino-aprendizagem para profissionais de saúde sobre o delirium em idosos hospitalizados. Método: Revisão integrativa realizada nas bases de dados US Nacional Library of Medicine (PubMed), Web of Science (WOS), Cumulative Index to Nursing & Allied Health Literature (CINAHL), Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS), Embase e Scopus. Foram incluídos os artigos publicados em periódicos científicos sem determinação do período de publicação e excluídos artigos não disponíveis na íntegra, teses, dissertações, resumos de congresso, anais e editoriais. Resultados: A amostra desta revisão foi constituída por quatro artigos, publicados entre os anos de 2015 e 2020, sendo a maioria dos autores enfermeiros. A tecnologia digital utilizada em três estudos foi o e-learning e, em um, uma palestra interativa com utilização do Power Point®. Considerações finais: Observou-se a necessidade de realizar mais pesquisas direcionadas a esse tema, uma vez que as tecnologias educacionais surtiram efeito positivo no conhecimento da equipe de saúde sobre o delirium no idoso hospitalizado e, consequentemente, no cuidado ao paciente.
SEGURANÇA DO PACIENTE NA TERAPIA MEDICAMENTOSA DE ADULTOS E IDOSOS NO AMBIENTE HOSPITALAR: REVISÃO INTEGRATIVA
Authors: MUNIZ EMELLEN , De Carvalho e Lemos Goulart Maithê , Eugenio Ana Caroliny , Vieira Pereira Ávila Fernanda Maria , Garcia Bezerra Góes Fernanda , Cerqueira Santos Santana da Silva Aline
Published: November 2023

Objetivo: analisar a literatura científica acerca da segurança do paciente e os erros na terapia medicamentosa em adultos e idosos internados no ambiente hospitalar. Método: revisão integrativa da literatura, entre 2018 e 2023, em seis diferentes recursos informacionais. Foram realizadas combinações com os descritores “Adulto”, “Idoso”, “Erros de medicação” e “Segurança do Paciente”. Resultados: foram analisados 22 artigos que atenderam aos critérios de inclusão. Os estudos demonstram que os principais erros de medicação estão relacionados ao preparo e administração de medicamentos. As principais metodologias para promoção da segurança do paciente e prevenção dos erros utilizaram tecnologias como consulta de bulas por QRcode e prescrições eletrônicas. Conclusão: as tecnologias possibilitam a adoção de medidas eficazes para prevenir os erros e garantir a segurança do paciente, destacando a responsabilidade dos profissionais de saúde na implementação de estratégias que garantam uma terapia medicamentosa segura e eficaz para o paciente adulto e idoso.
Palavras-chave: Adulto; Idoso; Erros de medicação; Segurança do paciente.
Changes of erythrocytes, hemoglobin and erythrocyte indices in cats with enterocolitis of unknown etiology
Authors: Karpenko L. , Bakhta A. , Pogodaeva P. , Bokhan P.
Published: November 2023

Purpose: Study red blood parameters in a group of cats with enterocolitis of unknown etiology using standard hematological research methods.

Materials and methods. During the study, standard methods of hematological analysis were used: erythrocyte counting was performed in a Goryaev chamber using whole blood diluted with isotonic sodium chloride solution 200 times, counting was carried out using a light-optical microscope Miromed-2 var. 3-20 inf. lens x8, eyepiece x10; the amount of hemoglobin was determined by the colorimetric method, diluting whole blood 200 times with a solution of 0,04 % ammonia on a Microlab-540 device; hematocrit value was determined by centrifugation using a Vilitek DSC-100MH-2 hematocrit centrifuge; the reaction to the erythrocyte sedimentation rate was performed in Panchenkov pipettes; erythrocyte indices and blood color index were calculated using generally accepted formulas.

Results. Thanks to the data obtained, we concluded that disruption of enzymatic processes, deterioration of absorption in the intestine and imbalance of symbiont microflora caused by enterocolitis can lead to the development of anemic conditions, manifested by changes in red blood parameters.
Synchronization of the reproductive cycle is bright for the regulation of lambing
Authors: Khusnetdinova N. , Iolchiev B.
Published: November 2023

Purpose: to study the effect of the duration of the use of progesterone for synchronization of the sexual cycle and the elaboration of the Dorper breed in the reproduction season.

Materials and methods. The object of the study was bright (n = 43) of the Dorper breed. Yarok was synchronized by the introduction of pessaries with progesterone (sidr) and injection on the day of removal of the CIDR of a chorionic gonadotropin of horses (HCH) in a dosage of 500 ME. Sheep were divided into three groups: I group (n = 13) – for 9 days a CIDR with progesterone (CIDR® OVIS, Zoetis, Madrid, Spain) was introduced for 9 days; Group II (n = 9) – CIDR was introduced for 11 days; Group III (n = 21) – CIDR was introduced for 13 days. In all three groups on the day of removal of the pessary, intramuscular injection of the HCL 500 IU is made. Upon completion of synchronization, observations of the signs of estrus were observed within 72 hours. Jacket was judged by the beginning of the estrus, when the state of immobility and the allowance of the ram of the ram was recorded. The duration of estrus was measured from the moment of the first intercourse until the sheep began to reject the male.

Results. The average interval between the removal of the pessary and the beginning of estrus in three groups was: in the first group – 38,7±5,1 hours; in the second group – 34,6±5,8 hours; In the third group – 52,4±4,4 hours. The minimum time from the extraction of CIDR to the beginning of the estrus was installed in the first group – after 12 hours, the maximum time was recorded in the third group – 96 hours.

Conclusion. The reliable effect of progesterone containing a gestagen drug on the reproductive indicators of the fierce, mainly at the beginning of the estrus, has been demonstrated. The most optimal is the use of CIDR with a constant rate of progesterone release by 9-11 days, since these groups have a 100% reaction to hormonal treatment.
Comprehensive Analysis of Regulated Cell Death in Intracranial Aneurysms
Authors: Zhu Jianyu , Wang Zhicheng , Li Jiebo , Kang Dezhi
Published: November 2023

Background: Abnormalities in regulated cell death (RCD) are involved in multiple diseases. However, the role of RCD in intracranial aneurysms (IA) remains unknown. The aim of this study was to explore different RCD processes in the pathogenesis of IA. Methods: Four microarray datasets (GSE75436, GSE54083, GSE13353, GSE15629) and one RNA sequencing (RNA-seq) dataset (GSE122897) were extracted from the Gene Expression Omnibus (GEO) database. The microarray datasets were merged to form the training set, while the RNA-seq dataset was used as the validation set. Differentially expressed genes (DEGs), gene set enrichment analysis (GSEA), and gene set variation analysis (GSVA) were used to investigate the role of different types of RCD, including apoptosis, necroptosis, autophagy, ferroptosis and pyroptosis in the formation of IA. A novel cell death classification system for IA was established using an unsupervised consensus clustering algorithm based on cell death signature genes. Differences in functional enrichment, cell death-related regulators, and immune infiltration between two cell death clusters were evaluated. Finally, predictive genes were identified using the least absolute shrinkage and selection operator (LASSO) regression, random forest and logistic regression, allowing a prediction model to be constructed for IA rupture. Results: Multiple RCD processes were significantly activated in IAs compared to controls. A total of 33 signature genes related to cell death were identified. The IA samples were divided into two clusters based on the cell death signature. The cell death-high subtype had a relatively higher rate of rupture, and higher enrichment levels for multiple cell death processes and several signal transduction and immune-related pathways. Immune infiltration analysis showed that cell death scores were correlated with multiple immune cell types, including macrophages, mast cells, T cells and B cells. A six-gene prediction model was constructed to predict rupture. The area under curves (AUCs) for predicting rupture in the training and validation cohorts were 0.924 and 0.855, respectively. Conclusions: Comprehensively analysis of RCD in IA and found that multiple RCD types are likely to be involved in IA formation and rupture. These cell death processes were correlated with inflammation and immunity. We present novel insights into the mechanism of IA pathogenesis that should help to guide further research.
Association of Accelerometer-Measured Sedentary Time and Physical Activity with Arterial Stiffness and Vascular Aging in the General Spanish Population, Analyzed by Sex
Authors: Gómez-Sánchez Leticia , Gómez-Sánchez Marta , Rodríguez-Sánchez Emiliano , Lugones-Sánchez Cristina , Tamayo-Morales Olaya , Gonzalez-Sánchez Susana , de Cabo-Laso Angela , García-Ortiz Luis , Gómez-Marcos Manuel A. , the EVA Investigators on behalf of
Published: November 2023

Background: In this study we analyzed the association between physical activity and sedentary lifestyle with vascular aging in Spanish populations aged 35–75 years. Methods: A cross-sectional study was developed, in which 501 subjects aged 35–75 years were recruited. Physical activity and sedentary time were measured with an accelerometer (Actigraph GTX3) for a week. We measured carotid–femoral pulse wave velocity (cfPWV) by a Sphygmo Cor® device and carotid intima-media thickness (cIMT) by ultrasound (Sonosite Micromax®). The vascular aging index (VAI) was calculated as described in the literature. Vascular aging was defined considering the 25th and 75th percentiles by age and sex of cfPWV and VAI, presence of vascular injury, type-2 diabetes mellitus or arterial hypertension. Individuals were classified into three groups: healthy, normal, and early vascular aging. Results: The mean age of the sample was 55.90 ± 14.24 years, 50% being women. Total physical activity was negatively associated with cfPWV (β = –0.454) and VAI (β = –1.845). Similarly, the number of steps per day obtained a negative association with cfPWV (β = –0.052) and VAI (β = –0.216), while sedentary time showed a positive association with cfPWV (β = 0.028) and VAI (β = 0.117). In the analysis by sex, the results showed similar values. The odds ratio (OR) of total physical activity of subjects classified as early vascular aging (EVA) with regarding those classified as healthy vascular aging (HVA) was 0.521 (95% confidence interval [CI] 0.317 to 0.856) for cfPWV, and 0.565 (95% CI 0.324 to 0.986) for VAI. In terms of the number of steps per day, the OR was 0.931 (95% CI 0.875 to 0.992) for cfPWV and 0.916 (95% CI 0.847 to 0.990) for VAI and for sedentary time the OR was 1.042 (95% CI 1.011 to 1.073) for cfPWV and 1.037 (95% CI 1.003 to 1.072) for VAI. The OR of subjects classified as vigorous physical activity was 0.196 (95% CI 0.041 to 0.941) using cfPWV and 0.161 (95% CI 0.032 to 0.820) using VAI. In the analysis by sex, the results showed an association in men when cfPWV was used and an association in women when VAI was used to define vascular aging. Conclusions: The results of this study indicate that the more time spent performing physical activity and the less sedentary time, the lower the arterial stiffness and the probability of developing early vascular aging. Clinical Trial Registration: The study was registered in ClinicalTrials.gov (number: NCT02623894).
Correlation Analysis of Gensini Score in Diabetic Patients with Coronary Heart Disease
Authors: Qi Jinyue , Wang Yunzhe , Liu Zhiyu , Yu Fengyi , Tang Junnan , Zhang Jinying
Published: November 2023

Background: Assessment of risk factors is essential for clinical diagnosis and prevention in patients with both diabetes mellitus (DM) and coronary heart disease (CHD). In the present study we investigated correlation of the Gensini score with the incidence of major adverse cardiac and cerebrovascular events (MACCEs) in patients with DM and CHD. Methods: A total of 802 DM patients with CHD admitted to the First Affiliated Hospital of Zhengzhou University and who met the inclusion criteria were enrolled in the study. The median follow-up time for these patients was 3000 days (range 382.5–3000). Receiver operating characteristic (ROC) curves for the Gensini score were generated and the area under the curve (AUC) was calculated. Patients were divided into two groups based on the Gensini score cut-off value. Univariate and multivariate Cox proportional hazard regression analysis was used to identify the risk factors associated with MACCEs. The incidence of MACCEs in the two groups was compared using Kaplan-Meier analysis. Results: The AUC of the ROC curve was 0.675. The maximum Youden’s index was 0.248 at a Gensini score cut-off value of 74.8605. This gave a sensitivity and specificity for the prediction of MACCE of 68.8% and 56%, respectively. A high Gensini score was a risk factor for MACCEs, and the incidence of MACCEs was significantly greater in the high Gensini score group compared to the low Gensini score group. Conclusions: A high Gensini score is a risk factor for patients with DM and CHD and is associated with a high incidence of MACCEs. Clinical Trial Registration: The details of study design are registered on http://www.chictr.org.cn (identifier: ChiCTR-2200055450).
Alexander Elenkin — the founder of cryptogamic botany in Russia
Authors: Andreev M. P. , Potemkin А. D.
Published: November 2023

Alexander Alexandrovich Elenkin is considered as the founder of the Russian lichenological school and one of the founders of other areas of cryptogamic botany in Russia — algology, mycology, phytopathology, and bryology. Elenkin was born 150 years ago in Warsaw, but almost all his life since 1898 he worked at the Botanical Institute in St. Petersburg. Elenkin has created the Cryptogamic Herbarium, in the walls of which brilliant scientists, specialists in various fields of cryptogamic botany grew up under his leadership. The life of the talented and enthusiastic scientist, teacher and organizer, who devoted himself entirely to science, was not easy, especially at the end, and tragically ended in 1942 in Kazan.
The heritage and bibliography of A. A. Elenkin
Authors: Potemkin A. D. , Itsyk T. V. , Makeeva E. K.
Published: November 2023

A. A. Elenkin’s contribution to the development of botany in Russia is multifaceted: as a scientist, organizer, editor, and popularizer of science. The most important aspect of Eleinkin’s heritage is the establishment of the foundations for the development of cryptogamic botany in Russia. The presented bibliography of 472 publications, including 201 critical reviews at the end of the list, is based on a generalization of previously published bibliographies, a detailed list of works by A. A. Elenkin until January 1, 1939, various publications and reprints. The titles and references to most publications have been verified from primary sources. Elenkin published 17 monographs with a volume of almost 5 000 pages, 87 works on algae and algology, 96 on lichens and lichenology, 55 publications on fungi and phytopathology, and 16 on mosses, 18 popular scientific publications, including 6 monographs, 1 article on microbiology, 1 on entomology. The article provides a complete bibliography of A. A. Elenkin and selected thematic lists in electronic supplements.