bluuebunny/crossref_metadata_2025 huggingface dataset:
Interacciones digitales y desigualdad de género: Un estudio sobre el uso de Instagram entre alumnado universitario
Authors: Piñeiro-Otero Teresa , Martínez-Rolán Xabier
Published: December 2024

El presente estudio explora cómo las redes sociales, particularmente Instagram, se convierten en espacios donde se reproducen y amplifican las desigualdades de género y la violencia simbólica. Utilizando una metodología cualitativa basada en grupos de discusión, el estudio analiza las experiencias de alumnado universitario en entornos digitales. Los resultados revelan que Instagram actúa como un espacio hostil para las mujeres, quienes enfrentan altos niveles de acoso y presión para cumplir con estándares de belleza hegemónicos. Aunque Instagram se presenta como una plataforma de empoderamiento y autoexpresión, el presente estudio concluye que la autoexposición y la autoobjetivación perpetúan estructuras de poder patriarcales, que obligan a las mujeres a adaptarse a roles tradicionales de género. Las dinámicas digitales impulsadas por el anonimato y la ausencia de restricciones eficaces intensifican el riesgo para las mujeres, aumentan las interacciones no deseadas y la vulnerabilidad ante violencias digitales. La investigación sugiere la urgencia de una educación en igualdad que aborde la crítica a estas dinámicas para construir espacios digitales seguros.
Torres Guijarro, Soledad (coord.). (2024). Hackeamos o patriarcado. Unha análise do machismo dixital.
Authors: González Liste Ana
Published: December 2024

Hackeamos o patriarcado. Unha análise do machismo dixital reúne a máis de vinte investigadoras e investigadores e está coordinado por Soledad Torres Guijarro, profesora na Escola de Enxeñaría de Telecomunicación da Universidade de Vigo. O volume, publicado na colección Feminismos da Editorial Galaxia, recompila sete traballos de investigación relacionados co machismo na rede, catro dos cales foron desenvolvidos pola Cátedra de Feminismos 4.0 da Uvigo, co-financiada pola Deputación de Pontevedra sobre os modos en que se opera o machismo dixital na actualidade.
Pengaruh Pengelolaan SDM terhadap Inovasi Bagi Pelaku UMKM di Kota Makassar
Authors: Perwira Iwan , Hernita Hernita , Erwin Erwin , Efshaliany Putri Nurul , Saputra Saputra , Palisuri Palipada
Published: December 2024

Penelitian ini bertujuan untuk menganalisis pengaruh Pengelolaan Sumber Daya Manusia terhadap Tingkat Inovasi UMKM di Kota Makassar. Dengan menggunakan pendekatan penelitian kuantitatif, data dikumpulkan dari 100 responden melalui kuesioner terstruktur. Validitas dan reliabilitas Instrumen diuji menggunakan SPSS versi 23, memastikan akurasi dan konsistensi pengukuran. Temuan penelitian mengungkapkan bahwa Pengelolaan Sumber Daya Manusia mempunyai dampak positif dan pengaruh signifikan terhadap Inovasi Bagi Pelaku UMKM. Hasil analisis regresi menunjukkan bahwa koefisien regresi Pengelolaan Sumber Daya Manusia sebesar 0,562 dengan nilai signifikansi sebesar 0,000 (p < 0,05). Hal ini menunjukkan bahwa peningkatan kegiatan Pengeloalaan Sumber Daya Manusia dapat meningkatkan Inovasi Bagi Pelaku UMKM. Bahwa Koefisien beta sebesar 0,521 menunjukkan kekuatan pengaruh sedang. Hasil tersebut menggarisbawahi pentingnya bagi pelaku usaha UMKM untuk mengoptimalkan potensi lokal dalam menciptakan produk yang sesuai dengan kebutuhan dan preferensi konsumen sehingga tidak hanya mendorong kemajuan individu tetapi juga menciptakan lapangan kerja baru dan mendorong perputaran perekonomian di Makassar. Hal ini berkontribusi terhadap pertumbuhan ekonomi kota secara keseluruhan.  Penelitian ini memberikan kontribusi baik secara teoritis maupun praktis dengan menekankan Peran Pengelolaan Sumber Daya Manusia sebagai upaya peningkatan inovasi di era industri yang sangat kompetitif.
This research aims to analyze the influence of Human Resource Management on the Innovation Level of MSMEs in Makassar City. Using a quantitative research approach, data was collected from 100 respondents through a structured questionnaire. Instrument validity and reliability were tested using SPSS version 23, ensuring measurement accuracy and consistency. The results of the regression analysis show that the Human Resource Management regression coefficient is 0.562 with a significance value of 0.000 (p < 0.05). This shows that increasing Human Resource Management activities can increase innovation for Micro, Small, Medium and Enterprises (MSMEs) actors. That the beta coefficient of 0.521 indicates a moderate strength of influence. These results underline the importance for Micro, Small, Medium and Enterprises (MSMEs) business actors to optimize local potential in creating products that suit consumer needs and preferences so that they not only encourage individual progress but also create new jobs and encourage economic turnaround in Makassar.  This research makes contributions both theoretically and practically by emphasizing the role of Human Resource Management as an effort to increase innovation in a highly competitive industrial era.
Analisis Tingkat Kerusakan Bangunan Pada Gedung Utama SMPN Satap Raja
Authors: Saputra Anggi , Sudirman Sudirman , Fikri Muhammad
Published: December 2024

Penelitian ini bertujuan untuk mengetahui tingkat kerusakan yang terjadi pada bangunan gedung SMPN Satap Raja. Jenis penelitian yang akan digunakan adalah penelitian kuantitatif dengan observasi objek yang digunakan peneliti untuk mendapatkan data sebagai deskriptif permasalahan yang ada pada objek penelitian. Hasil penelitian menunjukkan persentase total kerusakan visual pada seluruh komponen bangunan SMPN Satap Raja tiap-tiap ruangan, yaitu. Kelas 7 sebesar 10,06 %, Kelas 8 sebesar 9,79 %, Kelas 9 sebesar 10,30%, Ruang Laboratorium sebesar 8,72%, Ruang Guru sebesar 0,65%, Ruang Kantor sebesar 0,44%, Ruang Tata Usaha sebesar 17,77% dan Ruang Perpustakaan sebesar 0,37%. Maka dapat disimpulkan Persentase tingkat kerusakan total pada seluruh komponen bangunan yaitu 8,41%, maka kategori kerusakan visual banguanan gedung utama SMPN Satap Raja merupakan kerusakan ringan. Yang mengkategorikan kondisi keseluruhan bangunan sebagai Kerusakan Ringan. Temuan ini menekankan pentingnya upaya pemeliharaan dan intervensi yang tepat waktu untuk memastikan keselamatan dan fungsionalitas bangunan, mengingat pentingnya peran bangunan ini dalam mendukung berbagai kegiatan di sekolah.
This research aims to determine the level of damage occurring to the building of SMPN Satap Raja. The type of research that will be used is quantitative research, such as object observation, which the researcher uses to obtain data as a descriptive account of the problems present in the research object. The research results show the total percentage of visual damage to all components of the SMPN Satap Raja building in each room, namely. Class 7 at 10.06%, Class 8 at 9.79%, Class 9 at 10.30%, Laboratory Room at 8.72%, Teacher's Room at 0.65%, Office Room at 0.44%, Administration Room at 17.77%, and Library Room at 0.37%. It can be concluded that the total damage percentage of all building components is 8.41%, thus the visual damage category of the main building of SMPN Satap Raja is classified as minor damage. Which categorizes the overall condition of the building as Minor Damage. These findings emphasize the importance of timely maintenance efforts and interventions to ensure the safety and functionality of the building, considering the significant role this building plays in supporting various activities at the school.
PENGARUH PENEMPATAN DAN LINGKUNGAN KERJA TERHADAP KINERJA PEGAWAI MELALUI ROTASI PADA PT PLN (PERSERO) UNIT PELAYANAN PELANGGAN PAREPARE
Authors: Syam Muhammad Nur , Abubakar Herminawati , Suriani Seri
Published: December 2024

Penelitian ini bertujuan untuk menganalisis pengaruh penempatan dan lingkungan kerja terhadap kinerja pegawai di PT PLN (Persero) Unit Pelayanan Pelanggan Parepare, dengan rotasi sebagai variabel intervening. Metode yang digunakan adalah desain penelitian asosiatif dan pendekatan kuantitatif, di mana data dikumpulkan melalui kuesioner, tinjauan pustaka, dan dokumentasi. Hasil penelitian menunjukkan bahwa lingkungan kerja memiliki pengaruh signifikan terhadap kinerja pegawai, sementara penempatan tidak memberikan pengaruh yang berarti ketika rotasi diikutsertakan sebagai faktor intervening. Temuan ini mengindikasikan perlunya kebijakan rotasi yang lebih baik dan lingkungan kerja yang mendukung, guna meningkatkan kinerja pegawai. Implikasi penelitian ini penting untuk manajemen dalam merumuskan strategi pengembangan sumber daya manusia yang lebih efektif.
This study aims to analyze the influence of placement and work environment on employee performance at PT PLN (Persero) Customer Service Unit Parepare, with rotation as an intervening variable. An associative research design and quantitative approach were employed, utilizing questionnaires, literature reviews, and documentation for data collection. The findings reveal that the work environment significantly impacts employee performance, while placement shows no substantial influence when rotation is considered an intervening factor. These results highlight the necessity for improved rotation policies and a supportive work environment to enhance employee performance. The implications of this research are vital for management in formulating more effective human resource development strategies.
PENGARUH KEPUASAN PELANGGAN DAN KUALITAS PELAYANAN TERHADAP KINERJA PERUSAHAAN PADA PT PLN (PERSERO) ULP MATTIROTASI
Authors: Basri Rifda , Said Miah , Yunus Muh. Kafrawi
Published: December 2024

Penelitian ini bertujuan untuk menganalisis pengaruh kepuasan pelanggan dan kualitas pelayanan terhadap kinerja perusahaan pada PT PLN (Persero) ULP Mattirotasi. Metode penelitian yang digunakan adalah metode kuantitatif dengan jenis korelasional. Populasi dalam penelitian ini adalah seluruh pelanggan PT PLN (Persero) ULP Mattirotasi di Kota Parepare, Sulawesi Selatan, yang berjumlah 60.111 pelanggan per 30 April 2024. Sampel penelitian ini sebanyak 100 pelanggan yang dipilih menggunakan teknik stratified random sampling untuk memastikan representasi yang seimbang dari berbagai jenis pelanggan. Hasil penelitian menunjukkan bahwa kepuasan pelanggan dan kualitas pelayanan secara signifikan mempengaruhi kinerja perusahaan. Kualitas pelayanan memiliki pengaruh yang lebih kuat dibandingkan dengan kepuasan pelanggan. Koefisien regresi untuk kualitas pelayanan adalah 0.798 dengan nilai t sebesar 12.037 dan nilai signifikansi <0.001, sedangkan koefisien regresi untuk kepuasan pelanggan adalah 0.192 dengan nilai t sebesar 2.848 dan nilai signifikansi 0.005. Dengan demikian, dapat disimpulkan bahwa peningkatan kualitas pelayanan dan kepuasan pelanggan merupakan faktor kunci dalam meningkatkan kinerja perusahaan. Penelitian ini memberikan rekomendasi bagi PT PLN (Persero) ULP Mattirotasi untuk fokus pada peningkatan kedua aspek ini guna mencapai kinerja yang optimal dan mempertahankan hubungan baik dengan pelanggan.
This study aims to analyze the effect of customer satisfaction and service quality on company performance at PT PLN (Persero) ULP Mattirotasi. The research method used is a quantitative method with a correlation type. The population in this study is all customers of PT PLN (Persero) ULP Mattirotasi in Parepare City, South Sulawesi, which totals 60,111 customers as of April 30, 2024. The sample of this study is 100 customers who are selected using stratified random sampling techniques to ensure a balanced representation of various types of customers. The results of the study show that customer satisfaction and service quality significantly affect the company's performance. Service quality has a stronger influence compared to customer satisfaction. The regression coefficient for service quality was 0.798 with a t-value of 12,037 and a significance value of <0.001, while the regression coefficient for customer satisfaction was 0.192 with a t-value of 2,848 and a significance value of 0.005. Thus, it can be concluded that improving service quality and customer satisfaction are key factors in improving company performance. This study provides recommendations for PT PLN (Persero) ULP Mattirotasi to focus on improving these two aspects to achieve optimal performance and maintain good relationships with customers.
Pengaruh Ukuran Perusahaan, Umur Perusahaan Dan Solvabilitas Terhadap Nilai Perusahaan Dengan Variabel Intervening Profitabilitas Pada Perusahaan Sektor Manufaktur Makanan Dan Minuman Yang Terdaftar Di Bursa Efek Indonesia Tahun 2017- 2021
Authors: Rahman Yudi , Fakhri  , Fauziannor  , Halimi M. Rizal
Published: December 2024

Tujuan dari penelitian ini adalah untuk mengetahui Pengaruh Ukuran Perusahaan, Umur Perusahaan dan Solvabilitas Terhadap Nilai Perusahaan dengan Variabel Intervening Profitabilitas pada Perusahaan Sektor Manufaktur Makanan dan Minuman yang terdaftar di Bursa Efek Indonesia  Tahun 2017- 2021. Jenis Penelitian ini adalah penelitian kausalitas kuantitatif Pendekatan kausalitas yaitu meneliti hubungan sebab-akibat antara dua variabel atau lebih. Penelitian kausal menjelaskan pengaruh perubahan variasi nilai dalam suatu variabel terhadap variasi nilai variabel lain. Teknik analisis data yang digunakan adalah menggunakan PLS (Partial Least Square) dengan bantuan Smart PLS Ver 3 For Windows. Hasil penelitian menunjukan bahwa Ukuran perusahaan tidak berpengaruh secara langsung dan signifikan terhadap Nilai Perusahaaan, Umur perusahaan tidak berpengaruh secara langsung dan signifikan terhadap Nilai Perusahaan, Solvabilitas berpengaruh secara langsung dan signifikan terhadap Nilai perusahaan, Ukuran perusahaan  tidak berpengaruh secara langsung dan tidak signifikan terhadap Profitabilitas, Umur perusahaan tidak berpengaruh secara langsung dan tidak signifikan terhadap Profitabiltas, Solvabilitas berpengaruh secara langsung dan signifikan terhadap Profitabilitas, Nilai perusahaan berpengaruh secara langsung dan signifikan terhadap Profitabilitas,Tidak adanya Intervening antar Nilai perusahaan dan Profitabilitas terhadap Ukuran perusahaan pada Perusahaan Makanan dan Minuman yang terdaftar di Bursa Efek Indonesia, adanya Intervening antar Nilai perusahaan dan Profitabilitas terhadap Umur perusahaan pada Perusahaan Makanan dan Minuman yang terdaftar di Bursa Efek Indonesia,Tidak adanya Intervening antar Nilai perusahaan dan Profitabilitas terhadap Solvabilitas pada Perusahaan Makanan dan Minuman yang terdaftar di Bursa Efek Indonesia.
Kata kunci :  Ukuran Perusahaan,Umur Perusahaan dan Solvabilitas Terhadap Nilai Perusahaaan dengan Variabel Intervening Profitabilitas
Revitalizing the Research Ecosystem in Eastern Africa: Strategic Policies, Collaborative Partnerships, and Innovation-Driven Growth
Authors: Khan Dr. Samina , Idle Dr. Ahmed Farah
Published: December 2024

Research in Eastern Africa has enormous potential in catalyzing socio-economic development but its challenges are apparent; funding, unfavorable infrastructure, fragmented policies, and the problem of brain drain. The present research focuses on the approaches for improving research policies in the region to enhance health, agriculture, and climate change research through policy reform, partnership, and innovation for competitiveness. That is why if Eastern Africa synchronizes its research investments with national and regional development priorities, strengthens public private partnerships, and encourages innovation at the local level, systemic barriers to progress can be overcome. Beneficial cases like Kenya M-Pesa, Rwandan ICT polys, as well as Ethiopia renewable energy study show how right track solutions make a difference. The remedies suggested in this research involve the need to increase financial investment in research and development to levels comparable to the rest of the world, creating research networks regionally and extending innovation hubs inclusively and scalable. All these strategies are meant to foster a coherent and stable architecture of research systems to place Eastern Africa as an innovation frontier in sustainable development.
Keywords: Eastern Africa, Research Ecosystem, Policy Reform, Strategic Partnerships, Innovation, Socio-economic Growth, Sustainable Development
Integrating Edupreneurship into Higher Education: Challenges, Opportunities, and Strategic Pathways in Sindh, Pakistan
Authors: Jumani Sakina , Kazimi Prof. Dr. Anjum Bano
Published: December 2024

Abstract
This research aims to investigate the incorporation of edupreneurship into higher education curriculum in Sindh, Pakistan while focusing on entrepreneurial requirements, perception of faculty, and student interactions. In-depth interviews were conducted with 24 faculty members from numerous universities with issues like lack of resources and uncontented instructional models identified, as well as possibilities of collaboration between industries and academies. The analysis has been done using the Nvivo software. These findings point to the need for policy changes, development of professional learning and lesson studies that promote innovation and entrepreneurial dispositions for students. Recommendations, therefore, focus on ways of improving the effectiveness of edupreneurship in the higher learning institutions.
Keywords: Edupreneurship, Higher Education, Entrepreneurship Education, Faculty Perceptions, Curriculum Alignment
Adaptive Res-LSTM Attention-based Remaining Useful Lifetime Prognosis of Rolling Bearings
Authors: Najdi Boubker , Benbrahim Mohammed , Kabbaj Mohammed Nabil
Published: December 2024

Predicting the Remaining Useful Lifetime (RUL) of bearings is crucial for the maintenance and reliability of rotating machinery. This paper presents a novel approach utilizing PRONOSTIA and XJTU-SY datasets for RUL prediction. The proposed methodology leverages Synchrosqueezing Wavelet Transform (SSWT) and Random Projection (RP) to extract significant features from vibration signals. These features are then fed into a Residual Network (ResNet) combined with a temporal attention layer, followed by a Long Short-Term Memory (LSTM) model, referred to as the Adaptive Residual Attention LSTM (ARAL), to assess the Health Indicator (HI) of the bearings. Notably, an exponential data labeling technique is employed instead of traditional linear labeling, enhancing the robustness of the HI assessment. Following the HI estimation, the three-sigma method is applied to identify the degradation starting point. Subsequently, Gaussian Process Regression (GPR) is utilized to predict the RUL from this point forward. The proposed method demonstrates superior performance compared to existing techniques, providing more accurate and reliable RUL predictions. Experimental results show that this integrated approach effectively captures the complex degradation patterns of bearings, making it a valuable tool for prognostics and health management in industrial applications.
SLEEP PATTERNS AND QUALITY AMONG POST-GRADUATE MEDICAL STUDENTS: IMPACT OF CLINICAL RESPONSIBILITIES AND DEMOGRAPHIC FACTORS
Authors: Dwivedi Anuj
Published: December 2024

Background: Sleep is critical in overall health, cognitive functioning, and emotional well-being. Postgraduate medical students often experience sleep disturbances due to demanding academic schedules,
clinical responsibilities, and stress. Aim and Objective: To evaluate sleep patterns and quality among post-graduate medical
students and examine variations based on age, gender, and departmental afliation. Materials and Methods: A crosssectional study was conducted among post-graduate medical students. Sleep patterns were assessed using self-reported
sleep diaries, which recorded parameters such as sleep efciency, latency, wake after sleep onset, subjective sleep quality, and
morning refreshness. Participants were stratied by age, gender, and departmental afliation (clinical vs. non-clinical).
Statistical analyses were performed to compare sleep parameters across groups, with signicance set at p < 0.05. Results:
Most participants were aged 25–30 years, with no signicant differences in sleep parameters observed among different age
groups. Gender-based comparisons revealed slightly better sleep efciency and subjective sleep quality in females than
males, though these differences were not statistically signicant. Clinical students demonstrated signicantly poorer
subjective sleep quality (mean score 2.52 vs. 1.24; p = 0.006) and morning refreshness (mean score 2.62 vs. 1.20; p = 0.003) than
non-clinical students. Sleep efciency, sleep onset latency, and wake after sleep onset did not signicantly differ between the
two groups. Conclusion: Clinical post-graduate students experience signicantly poorer sleep quality and reduced morning
refreshness than their non-clinical counterparts, likely due to the demanding nature of clinical training. No signicant
variations in sleep patterns were observed across age groups or genders. These ndings underscore the need for targeted
interventions, including work schedule optimization and stress management strategies, to improve this population's sleep
health and overall well-being. Future research should explore longitudinal trends and the effectiveness of these interventions.
PREVALENCE OF COPD AND ITS ASSOCIATED FACTORS IN ADULTS IN URBAN SLUMS OF MEERUT: A CROSS-SECTIONAL STUDY.
Authors: Lal Roshan , Jain Seema , Bano Tanveer , Singh Ganesh
Published: December 2024

Background: Chronic Obstructive Pulmonary Disease (COPD) is the third leading cause of death worldwide, particularly in low- and middleincome countries where exposure to tobacco smoke and biomass fuels is prevalent. Urban slums, characterized by overcrowding and poor
ventilation, amplify these risks. Objectives: 1)To find out the prevalence of COPD. 2) To find out the association of COPD with age, gender and
smoking status. Material & Methods: A cross-sectional study was conducted on 277 adults aged 35 years and above residing under the area
covered by Urban Health Training Centre, Government Medical College Meerut, Uttar Pradesh from July 2023 to December 2023.Results: Out of
277 participants, 40 individuals fell into the GOLD 2 category, indicating moderate COPD with FEV1 values between 50% and 80% of predicted,
overall prevalence of COPD was 14.4%. The Prevalence of COPD was 21.7％among males and 9.3％among females. Among smokers, 33.3％had
COPD, while among non-smokers, 5.3％had COPD Conclusion: COPD rates increased with age, peaking in the 50-54 age groups and remaining
high in older groups. Males showed a higher prevalence of COPD compared to females. Smokers had higher prevalence of COPD as compared to
nonsmokers.
A CASE REPORT: PRESERVATION OF FERTILITY AMONG A PREGNANT WOMAN DELIVERED BY RECURRENT LAPAROTOMY WITH UTERINE SMOOTH MUSCLE OF UNCERTAIN MALIGNANT POTENTIAL.
Authors: Aljumah May Mohammed , Buhligah Roaa Abdullah , Al Braheem Gofran Mohammed
Published: December 2024

Uterine smooth muscle tumors of uncertain malignant potential (STUMP), a subcategory of uterine smooth muscle tumors is difficult to
diagnose.1Uterine leiomyoma , a smooth muscle tumor of uncertain malignant potential (STUMP) is mainly diagnosed among female in their 30s
and 40s.3 Around 3-12 % of pregnant women are reported to have uterine leiomyoma.4 The purpose of this study was to evaluate the clinical and
reproductive outcomes of a pregnant patient who was histologically diagnosed with uterine smooth muscle tumor of uncertain malignant potential
(STUMP), and were treated with cesarean section then conservatively. 24 years old female, a prime g Case Discussion: ravida, conceived
spontaneously after 6 years of myomectomy due to STUMP with recurrent STUMP. The pregnancy went uncomplicated and the woman delivered
by classical cesarean section without complication with preservation of fertility. This case will h Conclusion: elp shape future guidelines for
surveillance and management. Future studies should aim to identify biomarkers and histological or immune-histochemical markers to aid in
diagnosing tumors with the potential for malignant transformation.
THE IMPORTANCE OF CBCT IN DIAGNOSING AND TREATMENT PLANNING OF IMPACTED CANINES - A CASE REPORT
Authors: Lazarevska Bisera , Janeva Nadica , Sotarovska Vesna Jurukovska
Published: December 2024

In recent years, three-dimensional Cone Beam Computed Tomography (CBCT) has become a highly valued radiographic tool in dentistry, used
extensively for diagnosis, treatment planning and follow-up. 3D imaging has significantly enhanced diagnostic capabilities and improved various
dental practices, from routine assessments to the in-depth analysis of complex pathologies and congenital anomalies, making the dental care more
precise and reliable. In orthodontics, one of the primary applications of CBCT is in evaluating impacted canines. This article presents a case report
of a patient with an impacted left maxillary canine, assessed using 3D CBCT imaging. The CBCT scan provided detailed anatomical insights, such
as the labiolingual positioning of the impacted tooth, the extent of possible root resorption and its relationship with the roots of the adjacent teeth.
Accurate linear and angular measurements from the CBCT images allowed for precise localization of the impacted teeth, facilitating more effective
surgical exposure.
UNVEILING MEGALENCEPHALIC LEUKOENCEPHALOPATHY WITH SUBCORTICAL CYSTS (MLC): A CASE SERIES AND LITERATURE INSIGHT
Authors: Senthilkumar Preethi , Kumar Yogesh , Voltaire Priyan , Tarani J Sai , Yeslawath Nitishkumar
Published: December 2024

Megalencephalic leukoencephalopathy with subcortical cysts also known as Van Der Knapp disease which is an inherited autosomal recessive
disorder with a specific MRI features and a variable clinical course. On MRI, Frontal and temporal subcortical cysts are the diagnostic hallmark . It
usually presents with cerebellar, pyramidal signs and seizures. Megalencephaly can be detected early. It has been seen that it has been more
prevalent in north Indian population, however it has been seen globally. We encountered a patient who is a 9 year old old male child came with
history of developmental delay, seizures with psychotic features. four patients and describe the clinical and radiological features of these patients.
EVALUATING FLUID MANAGEMENT IN DIABETIC KETOACIDOSIS
Authors: JA Tyre, , T. Podesta, , NM. Tyre, , V. Silvestri,
Published: December 2024

Diabetic Ketoacidosis is a critical illness that requires aggressive fluid resuscitation, electrolyte correction, and glucose control. The specific
intravenous fluid used is a debatable topic among healthcare providers and hospitals. The controversy is due to the vastly different characteristics of
0.9% normal saline and lactated ringers. Normal saline, the standard of care, is more acidic and less physiologic when compared to lactated ringers.
Review articles and clinical trials were reviewed to gather information regarding the topic. One clinical trial compiled from numerous sub-group
studies shows promising results for lactated ringers being the superior fluid of choice. However, two smaller studies reviewed revealed
insignificant data. Due to the limited subjects studied in the clinical trials, this study cannot support or reject the idea that lactated ringers are
superior to normal saline in treating diabetic ketoacidosis.
HEMOGRAM PROFILE OF PATIENTS WITH TYPE 2 DIABETIC MELLITUS IN RURAL TERTIARY CARE REFERRAL HOSPITAL
Authors: Anoop Anoop , Kapoor Dhiraj , Manju Manju
Published: December 2024

Objectives: The objective of thisstudy isto help identify the hematological profile of patients withT2 diabetes Mellitus. Material and Method: -The
study was a cross-sectional observational study which was conducted in the Department of Medicine of Dr Rajendra Prasad Government Medical
College and Hospital, Kangra (at Tanda), a rural tertiary care referral hospital. Study duration: December 2022 to January 2023. Study Population:
T2DM-confirmed individuals attending theDiabetic clinic ofDrRPGMC,Tanda,Kangra after approvalfromthe InstitutionalEthicsCommittee (IEC).
Sample Size: 100. The mean age of patients was 63.27±10.64 years. (The hematocrit value (HCT), hemoglobin content, red blood cells count (RBCs)
and mean corpuscular volume (MCV) concentration with increased white blood cells counts (WBCs), mean erythrocyte hemoglobin concentration
(MCHC), mean corpuscular hemoglobin (MCH), lymphocytes and neutrophilslevels were performed. Results: Hematologicalstudiesin the diabetic
patients had HbA1C >8 showed significantly lower HCT values, hemoglobin content, RBCs count and MCV concentration than in the patients had
HbA1C<8. Greater total WBC counts, MCHC concentrations, MCH, lymphocytes and neutrophils counts were observed in the patients than in the
patients with HbA1C< 8. No differences were found between platelets counts in the diabetic patients having HbA1C> 8 and those patients had
HbA1C<8. Conclusions: The present study noted that the majority of the studied patients were female gender and belonged to the 61-70 years age
group.Thisstudy noted that 61.0%of patientswere havingHbA1c level>8%.Therewasfound a significant association betweenHBA1cwith patients‟
age and duration of diabetes. Early age and longer duration of disease isrelated to more cases of uncontrol diabetes. Eosinophils, RBC, PCV, and ESR
were significantly higherin the diabetes group ofHBA1c>8%in comparison toHBA1c≤8%.WhileMonocyte andMCVwere comparatively lowerin
the HBA1C >8% group in comparison to the HBA1c ≤ 8% diabetes group. DLC parameters, RBC, PCV, and ESR were significantly correlated with
diabetes profiles. Patients with T2DM are associated with significant alterations in various hematological parameters. Therefore, hematological
parameters should be routinely determined among T2DM patients for proper management and reduction of further complications. The study was
conductedaftergettingapprovalofthe Institutional ethics committee (No.IEC/86/2021).
THE EFFECT OF NANOCOMPOSITES RESIN ON THE AESTHETIC PROPERTIES. A SYSTEMATIC REVIEW.
Authors: Roslan Litah , Makandar Saleem D. , Hulikatti Aaqil Arshad
Published: December 2024

In this study the literature was systematically review the available evidence of the effect of nanocomposite resin restoration on aesthetic outcome.
The aims of this systematic review was to investigate the discolouration of nanocomposite after the certain period of time and also the polishing
outcome when compare to the other types of composite materials. The source from PubMed, Google Scholar and Science Direct database was
included. Screened titles and/or abstracts of 45789 unique studies. In total, 32 studies were selected for full-text reading, from which 20 were
included in the qualitative synthesis. The findings was the longest period of time is 6 months and show nanofilled composite resin has shown less
discolouration (p< 0.001) compared to other types of composite resins. The polishing of nano composite resin was superior compared to the other
types of composite resins. Different polishing systems have shown smoother surface compared to nanohybrid and other types of composite resin (p
< 0.05). Hence, few factors has impact to the discolouration outcome of composite resin. Aesthetic of composite resin is depends not just on the
composition but also the polishing part. Overall, nanocomposite is the best in terms of aesthetic and polishing outcome.
STUDY OF THE EFFECTS OF YOGIC EXERCISES ON PHYSIOLOGICALAND HEMATOLOGICAL FUNCTIONS IN YOUNG VOLUNTEERS
Authors: Gaur Vaibhav , Jain Manila
Published: December 2024

India had a glorious past of rich cultural heritage of its people. The knowledge of medicines in medical India expanded by number of further
additions by various Rishis and finally it let it birth to full-fledged science of health known as Ayurveda which involves treatment of various
diseases by indigenous drugs. In addition of Ayurveda a different system of medicines which does not involve any medicine but simply practice of a
well-organized physical posture known as Yoga was also practiced by ancient Indians even before the advent of Aryans in the Indus Valley. Method
and Methodology:The Present study was carried out on 17 male & 11 female, normal, healthy, young medical students of medical institute within
the age group of 18 to 22 years. Physiological and hematological parameters were measured initially. The yogic training was given under the
supervision of a yogic expert. These volunteers were subjected to practice 10 Asanas, 05 Pranayamas, 04 Mudras, and 05 Bundhas regularly for one
and half hour daily in the evening for a period of 03 months. The observations were recorded after 01 Month, 02 Months and 03 Moths periods.
Results: The Effects of Yogic Exercises on physiological and hematological function shows the gradual betterment from mean control after 3
months of Yogic Practices and statistically significant after 1 month, 2 months, and 3 months of Yogic Practices in all the parameters. Conclusion:
The mechanism of Physiological changes which are induced by Yogic training is not clear and a controversy regarding is still persists. Various
authors have given various reasons but none of them are widely accepted. The most accepted view is that yoga effects the autonomic nervous
system by decreasing sympathetic tone. The possible side of action may be hypothalamus which regulates the autonomic nervous system.
Predicting the effect of the Common Agricultural Policy post-2020 using an agent-based model based on PMP methodology
Authors: Baldi Lisa , Calzolai Sara , Arfini Filippo , Donati Michele
Published: December 2024

The objective of this study is to perform an ex-ante assessment of the potential impacts of agro-environmental measures included in the post-2020 Common Agricultural Policy (CAP), by estimating farmers’ responsiveness in adopting organic agricultural practices and an eco-scheme that incentivises extensive forage systems. This research is conducted by means of an Agent-Based Model (ABM), based on Positive Mathematical Programming (PMP), implemented in GAMS. The ABM facilitates the simulation of interaction among farmers, allowing for an analysis of farm heterogeneity. The PMP methodology adds a non-rational dimention to the farmers’ economic drivers. The model is calibrated using 2019 Farm Accountancy Data Network (FADN) data specific to the Emilia Romagna region in Italy. Our findings reveal significant impacts on land use, with a notable decrease in cereal cultivation in favour of protein and fodder crops. Moreover, structural shifts are observed, notably a decrease in the number of small-scale farms. We also assess environmental and economic implications, observing a modest reduction in CO2 equivalent emissions per hectare, an increase in water demand, and an overall economic stability among farms, as indicated by changes in gross margin per hectare.
A study of morphology and morphometry of scapula in North Indian population and its evolutionary significance
Authors: Sharma Ritika , Sharma Rajan , Singla Rajan Kumar , Kullar Jagdev Singh
Published: December 2024

Introduction. Morphometrics can quantify a trait of evolutionary significance and deduce something of their ontogeny or evolutionary relationships. The present study intends to establish the morphometric criterion of scapula in North Indians. This is of definite significance as bone morphology is known to be influenced by cultural, environmental and racial factors. Materials and methods. The present study was carried on 100 adult scapulae of unknown sex obtained from Department of Anatomy, Government Medical College, Amritsar. The parameters studied were length of scapula; maximum breadth of scapula; superoinferior length, transverse breadth and depth of supraspinous fossa; length of infraspinous fossa, maximum breadth of infraspinous fossa, infraspinous fossa breadth, groove for circumflex scapular vessels and its distance from lateral angle and inferior angle, ridge between origin of teres minor and teres major on lateral border of infraspinous fossa, length of attachment of teres minor on infraspinous fossa, length of attachment of teres major on infraspinous fossa; scapular index and infraspinous index. Results. The values of the parameters were found to be more on the right side except superoinferior length of supraspinous fossa, mean distance of the groove from the lateral angle and inferior angle. Mean scapular index and mean infraspinous index were 68.30 and 76.40 respectively. Discussion. The various morphologic parameters studied and morphometric values measured in our study can be used to compare the racial characteristics and study the evolutionary aspects in different populations.
Human coronary vessels: Distribution of cholinergic nerve fibres and age-related changes
Authors: Ciccarelli Antonello , Forte Flavio , Pindinello Ivano , Cofone Luigi , Galassi Francesco M. , Circosta Francesco , Papa Veronica , Taurone Samanta
Published: December 2024

Background. Cholinergic nerve fibres were studied in the human coronary vascular tree by means of acetylcholinesterase staining and  choline acetyltransferase activities on autopsy samples of coronary vessels (arteries, veins, and micro-vessels). Methods. Samples of human coronary vessels were harvested in younger and older subjects. Samples were exposed to the enzymatic and or immune staining for acetylcholinesterase and  choline acetyltransferase, two enzymes linked to the metabolism of acetylcholine. The morphological data were subjected to the quantitative analysis of images and to the statistical analysis of data. Results. Both acetylcholinesterase and  choline acetyltransferase activities are localised in the human coronary vessels. Structures resembling cholinergic nerve fibres are located in the extra-parenchymal and intra-parenchymal branches of these vessels. Discussion and Conclusions. The quantitative analysis of images and statistical analysis of data demonstrate that the cholinergic innervation of coronary vessels (especially the extra-parenchymal branches) is well represented. Moreover, in older subjects both the enzymes are strongly decreased. The extra- and intraparenchymal branches of the human coronary arteries and veins are provided with cholinergic nerve fibres, which could control the efferent sensitive pathways and the autonomic nerve fibres of the coronary vascular tree.
Chronic mastitis or breast cancer in The Charity by Francesco Salviati? An educational discussion
Authors: Paternostro Ferdinando , Lippi Donatella , Zucchini Elisa , Nori Jacopo , Galassi Francesco , Nerlich Andreas G. , Bianucci Raffaella
Published: December 2024

In the present communication, the painting La Carità (The Charity) by Francesco de Rossi, also known as Salviati (1510-1563), is examined from a multidisciplinary perspective, combining the following disciplines: human anatomy, palaeopathology and history of art. In the impossibility to establish a final diagnosis due to the artistic nature of the artwork, the anatomical alterations found on the iconographic representation are discussed in light of two alternative hypotheses, namely chronic mastitis or breast cancer. Once more the intersection between medicine and art can be found to be of excellent use both for increasing the ancient record of diseases and in an educational effort to train the eye of future physicians.
A forgotten debate in the history of medicine: vascular anastomoses, from open functional relationships to tight structural connections
Authors: Saccheri Paola , Crivellato Enrico , Travan Luciana
Published: December 2024

According to current anatomical nomenclature, vascular anastomoses are direct connections between blood vessels. The Greek word ‘anastomōsis’ means ‘opening’ and conveys the idea of ‘patency’ rather than ‘connection’. Anastomōsis, and the related term sunanastomōsis, originally referred to a mere approximation of the mouths of adjacent blood vessels – especially arterioles and venules – facing each other at their terminal ends. These vessels were not strictly connected and did not form anatomical units in the proper sense. Over time, however, the term anastomōsis underwent a significant semantic change and now denotes a closed, structured anatomical connection. How and when did this semantic shift occur? The aim of the present study was to evaluate the concept of anastomōsis in different historical periods from Antiquity to the Seventeenth century and to investigate how this entity gradually lost its original meaning of mere functional opening to acquire the notion of true anatomical structure.
The brain as a “hyper-network”: impact on neurophysiology and neuropharmacology
Authors: Guidolin Diego , Tortorella Cinzia , Anderlini Deanna , Marcoli Manuela , Agnati Luigi
Published: December 2024

Neuronal network architecture plays a crucial role as the structural substrate for the brain functions. Increasing evidence, however, indicates that, beside neural networks, to fully understand brain complex integrative actions glial cells and the diffusion of signaling substances in the network of extracellular fluid channels should also be considered. To account for this more complex architecture it has been proposed that all these networks are assembled into a so-called brain hyper-network, having as fundamental components the multi-partite synapses involving not only neurons, but also regulated by the astrocyte networks and fine-tuned by microglia and by pervasive signals diffusing in the interstitial channels of the extracellular matrix. The main features of this view of the central nervous system organization are here discussed. This complex network architecture can be of particular interest for neurophysiology, since it may represent a suitable structural counterpart of physiological mechanisms allowing goal-directed behavior. Furthermore, a model of brain organization integrating the activity of different CNS components may assist in the identification of new possible targets for the pharmacological treatment of CNS diseases. These aspects are also briefly discussed.
Autonomic functions of the cerebellum: Anatomical bases and clinical implications
Authors: Benagiano Vincenzo , Rizzi Anna
Published: December 2024

Traditionally, the cerebellum is viewed as a center for integrating vestibular and general proprioceptive sensory, enabling the processing of somatic motor responses essential for maintaining balance and posture. Moreover, the cerebellum regulates higher motor functions of the neocortex, which involve motor planning and coordination of movements, as well as nonmotor functions related to cognition and affectivity. In recent years, several studies have suggested that the cerebellum may play a role in regulating visceral functions. Although the specific neural pathways through which these visceral functions are mediated remain unclear, anatomical evidence to support these functions has been supplied by the detection of a feedback circuit that connects bidirectionally the cerebellum and the hypothalamus, the primary integrative center of the autonomic nervous system. This hypothalamocerebellar circuit strongly supports the idea of the cerebellum as a center of the autonomic nervous system.
Pengaruh PIO terhadap Keberhasilan Pengobatan Antidiabetik Oral pada Pasien DMT2
Authors: Mananna Esran , Hajrah Hajrah , Suparningtyas Juniza Firdha
Published: December 2024

Diabetes melitus tipe 2 adalah penyakit gangguan metabolik yang ditandai oleh kenaikan gula darah akibat penurunan sekresi insulin oleh sel beta pankreas dan ganguan fungsi insulin. Kepatuhan pengobatan merupakan salah satu faktor penting yang secara kuat memengaruhi terkontrolnya kadar gula darah. Oleh karena itu, dengan adanya Pelayanan Informasi Obat (PIO) dapat meningkatkan kepatuhan minum obat sehingga keberhasilan pengobatan dapat tercapai. Tujuan penelitian ini untuk mengetahui pengaruh pelayanan informasi obat terhadap keberhasilan pengobatan antidiabetik oral pada pasien diabetes melitus tipe 2. Pengambilan data dilakukan secara prospektif dengan penentuan sampel secara purposive sampling. Dari hasil penelitian pada 27 sampel didapatkan penderita diabetes melitus tipe 2 paling banyak pada perempuan sebesar 70,37%, usia 46-55 tahun dan usia 56-65 tahun sebesar 44,44%. Sebagian besar responden adalah IRT dengan persentase 55,55% dengan komorbid hipertensi sebesar 40,74%. Jenis obat paling banyak digunakan yaitu kombinasi obat metformin HCl dosis 500 mg dan glimepiride dosis 2 mg sebesar 40,74% dan penggunaan obat tunggal yaitu metformin HCl dosis 500 mg sebesar 37,03%. Pemberian PIO berpengaruh dalam meningkatkan kepatuhan minum obat dengan nilai signifikansi p= 0,000. Pemberian PIO berpengaruh dalam keberhasilan pengobatan yaitu terjadi penurunan kadar gula darah.
Pertukaran Tema Fantasi dalam Retorika Visual melalui Media Sosial
Authors: Pelu Dienda Anissa Deah Putri , Pelu Nurcahyadi
Published: December 2024

Artikel ini merupakan hasil penelitian yang dilandasi pemikiran Borman E. (1990) bahwa tema fantasi yang dipertukarkan dan menjadi narasi bersama sebuah kelompok akan menjadi daya kohesi kelompok. Sumber tema fantasi dalam penelitian ini adalah visual dalam foto yang diambil oleh kelompok remaja Negeri Hitu Lama, Maluku Tengah dan diunggah di media sosial. Daerah tersebut merupakan daerah pasca Konflik Ambon 1999 dan latar belakang masyarakatnya masih terikat pada adat, agama, sejarah, dan nilai-nilai hidup  nenek moyang mereka. Tujuan penelitian adalah menganalisis representasi visual dalam foto remaja Negeri Hitu Lama guna  menemukan tema fantasi dan makna dibaliknya. Penelitian dilakukan dengan menggunakan jenis kualitatif dengan  metode Photo Elicitation Interviews (PEI) dan Fantasy Theme Analysis (FTA), dan kerangka analisis  Symbolic Convergence Theory (SCT) oleh Ernest Borman.  Hasil penelitian menunjukkan bahwa di antara remaja Negeri Hitu Lama  bertukar tema fantasi perdamaian dan kemudian menjadi tema bersama. Namun, tema fantasi bersama tersebut terjadi karena dominasi pemerintah berbasis daerah (raja), dan pengalaman dalam pembentukan realitas simbolik. SCT tidak cukup untuk menjelaskan tema fantasi pada konteks struktur dominasi tradisional yaitu aktor kuasa tidak diulik.
Imagined Community: Refleksi Kognisi Masyarakat Muda terhadap Identitas Regional ASEAN
Authors: Rachmayani
Published: December 2024

Ada anggapan bahwa komunitas ASEAN merupakan imagined community yaitu komunitas hanya dalam bayangan hasil dari konstruksi sosial negara anggotanya, bukan proses yang berasal dari keterikatan yang bersifat alamiah. Artikel ini merupakan kajian literatur yang bertujuan menjelaskan dan mengonfirmasi argumen tersebut. Kajian akan diuraikan dan dianalisis dengan menggunakan pendekatan teori konstruktivisme. Hasil kajian menunjukkan bahwa sebagian besar warga negara anggota ASEAN, khususnya kaum muda, belum memiliki rasa keterikatan dengan komunitas ASEAN, kognisi we feeling terhadap ASEAN belum terbangun. Hal tersebut disebabkan belum maksimalnya program edukasi dan promosi nilai-nilai bersama. Temuan tersebut mengonfirmasi berlakunya anggapan atau argumen imagined community yang disematkan terhadap ASEAN. Implikasinya untuk mewujudkan sebuah komunitas dan menguatkan identitas regional membutuhkan upaya internalisasi nilai dan norma yang lebih maksimal dengan meminimalisir setiap hambatan yang ada, baik melalui jalur struktur yaitu sumber daya dan norma lembaga ASEAN maupun agency yaitu negara-negara anggotanya termasuk warga negaranya.
Students' Challenges in Learning Listening: A Case in SMAN 2 Tanjungpinang
Authors: Melany Apriyanti  , Rere Melvina  , Chemilia Azra Putri  , E. Nur Putri Wulandari  , Pohan Erwin
Published: December 2024

This study examines the challenges faced by students at SMAN 2 Tanjungpinang in developing listening comprehension skills in English as a Foreign Language (EFL). Using a qualitative approach, data were collected through listening tests and interviews with 35 students. The results identified key challenges, including limited vocabulary, unfamiliar topics, grammar knowledge deficits, fast speech, accent variations, unclear pronunciation, lack of practice, and environmental noise. These difficulties hinder students' ability to understand spoken English effectively. The findings suggest that targeted interventions, such as vocabulary-building activities, exposure to diverse accents, and improved classroom environments, are needed to enhance listening skills. This study provides valuable insights for teachers and policymakers to improve listening instruction in similar educational contexts.