bluuebunny/crossref_metadata_2025 huggingface dataset:
Vezetői stílusok a hivatásos állomány szemével: laissez-faire (ráhagyó)
Authors: Kovács István
Published: March 2021

A tanulmányban részleteiben elemzem Lewin egy vezetési stílusát (laissez-faire), majd azt egy a 2018. évben végzett „survey” felmérés eredményeivel vetem össze. A kutatás során a forráskritika, az analízis és szintézis dialektikus egysége mellett kvantitatív eszközöket is felvonultató statisztikai számítások elvégzésére volt lehetőségem, amely a korrelációs együttható, azaz a hatásfoknagyság mérésére is kiterjedt.
Legality of Construction Working Contracts as an Formil Agreement
Authors: Rahmawati Diana , Zakiyah Zakiyah , Arsyad Muhammad
Published: March 2021

The purpose of this study is to determine the form of construction work contracts and the legal consequences of construction work contracts that are not in accordance with the provisions of statutory regulations in the field of construction services. The legal research method used is normative legal research, which is a study of the prevailing laws and regulations which are particularly related to construction service contracts. This type of research is legal obscurity. A construction work contract is a type of formal agreement in which Law Number 2 of 2017 concerning Construction Services and its implementing regulations determines the procedures and conditions before the contract is made, including the form and content of the construction work contract, by determining the standard at a minimum, the contents of a construction service work contract that must be included in the construction work agreement by the parties. Since the construction work contract is a contract with mandatory conditions, the construction work contract is a formal agreement. This is if the construction work contract is made without paying attention to the provisions of laws and regulations in the field of construction services, both regarding the qualification requirements of a construction service provider, the procedure for selecting a service provider and the form and content of the construction service contract that has been determined by the law. As a juridical consequence, if the formal conditions are not fulfilled in a contract concerned, it is not legally enforceable or in other words it is a null and void contract (nietig, null and void).
ALGILANAN HİZMET KALİTESİNİN MÜŞTERİ MEMNUNİYETİNE ETKİSİ: CANOĞLU CAFE & RESTAURANT ÖRNEĞİ
Authors: ABDRAIM KYZY Nuruzat , SADYKOVA Guzel
Published: March 2021

alışmanın amacı, algılanan hizmet kalitesinin müşteri memnuniyetine olan etkisini incelemektir. Araştırmada hizmet kalitesi güvence ve heveslilik, empati, güvenilirlik, fiziksel kanıtlar boyutlarıyla temsil edilmiştir. Müşteri memnuniyeti hizmet sunan kurumdan, sunulan hizmetin içeriğinden ve diğer işletmelerle kıyaslandığında duyulan memnuniyet temelinde incelenmiştir. Kastamonu şehrinin merkezinde yer alan Canoğlu Cafe & Restaurant’ın müşterilerine yönelik gerçekleştirilen araştırmanın sonucunda hizmet kalitesinin tüm boyutlarının müşteri memnuniyeti üzerinde pozitif ve anlamlı etkileri olduğu ortaya çıkmıştır. Sunulan hizmete ilişkin kalite algısını pekiştirme, nitelikli ve gelişmiş iletişim becerilerine sahip çalışanlar tarafından yaratılan güven, duyarlılık, ilgili davranma konusundaki isteklilik, araç-gereç ve donanım yeterliliği, hizmetin içeriğine ilişkin yenilik, yaratıcılık ve farklılık yaratma ile sağlanabilir.
SOLID HOUSEHOLD WASTE DISPOSAL BY DOUBLE STAGE BURNING ON WALKING BEAM AND IN THE BUBBLED MELT
Authors: Olabin V.M. , Trukhan S.P. , Maksymuk O.B. , Nikitina I.V.
Published: March 2021

State of the problem of solid waste disposal at landfills has been analyzed. A combined method of two stages of solid waste incineration during the heating season has been proposed. The results of calculations of thermal balances of evaporation processes, burning on a movable bottom and in a bubbled melt, heating of air in the recuperator, heating of water in the contact heat exchanger, boiler and in the hot water supply system has been presented. It is shown that the elimination of the source of pollution in the form of solid waste in a two-stage method of incineration: on a walking step and then in a bubbled melt — makes it possible to get rid of secondary solid waste generated by traditional incineration. As a result of melting in the bubbled melt gases are formed, which contain the products of combustion and decomposition of solid waste and slag consisting of silicates and metal oxides. Bibl. 10, Fig. 3, Table 1.
Tatalaksana Gizi Pada Ibu Hamil Untuk Mencegah Risiko Stunting Pada Anak Di Puskesmas Jongaya
Authors: Safitri Asrini , Gayatri Sri Wahyuni , Kartika Irna Diyana
Published: March 2021

Stunting merupakan hambatan pertumbuhan yang diakibatkan kekurangan asupan zat gizi juga adanya masalah kesehatan yang berdampak pada perkembangan anak dari tahap awal yaitu saat konsepsi sampai tahun ke 3 atau ke 4 kehidupan anak, dimana keadaan gizi ibu dan anak merupakan faktor penting dari pertumbuhan anak. Stunting pada usia dini berhubungan dengan terjadinya gangguan tingkat kecerdasan anak, perkembangan psikomotorik dan kemampuan motorik halus. Stunting dipengaruhi oleh pendapatan keluarga, pengetahuan gizi ibu, pola asuh ibu, riwayat infeksi penyakit, riwayat imunisasi, asupan protein, dan asupan ibu. Asupan ibu terutama saat hamil merupakan salah satu faktor yang berperan penting. Gizi janin bergantung sepenuhnya pada ibu, sehingga kecukupan gizi ibu sangat memengaruhi kondisi janin yang dikandungnya. Ibu hamil yang kurang gizi akan menyebabkan gangguan pertumbuhan janin dalam kandungan. Dilakukan kegiatan penyuluhan, pengukuran antropometri  dan pembagian leaflet mengenai pentingnya asupan nutrisi selama kehamilan dalam mencegah risiko terjadinya stunting pada anak. Kegiatan ini dihadiri 40 orang ibu hamil umur kehamilan trimester I, II dan  III. Selama kegiatan kami tetap melakukan protokol kesehatan. Dari hasil pengukuran antropometri didapatkan 6 orang ibu hamil pada trimester III,24 orang trimester II dan 7 orang dengan status gizi baik pada trimester 1. Sedangkan status gizi kurang didapatkan 1 orang ibu hamil pada trimester I dan 2 orang trimester II. Kesimpulan : Dalam mencegah risiko terjadinya stunting pada anak, perlu pemberian nutrisi yang tepat pada ibu hamil sejak di trimester pertama agar tidak terjadinya risiko malnutrisi yang akan berdampak pada anak nantinya
PKM Sosialisasi Penggunaan Antibiotik dan Efek Penyalahgunaan Antibiotik Guna Pengendalian Resistensi Antibiotik Di Desa Sanrobone Kecamatan Sanrobone Kabupaten Takalar
Authors: Yanah Rasfa , Arfah Arni Isnaini , Midah Zulfah
Published: March 2021

Istilah antibiotik mencakup semua antimikroba yang digunakan dalam pengobatan dan profilaksis infeksi bakteri. Antibiotik merupakan obat yang sering diresepkan untuk pasien namun sering terjadi penggunaan yang tidak tepat dan berakibat terjadinya resistensi terhadap kuman. Hal ini terjadi karena kurangnya pengetahuan masyarakat tentang penggunaan antibiotik yang tepat sehingga menyebabkan resistensi antibiotik. Saat ini, pengetahuan masyarakat tentang resistensi antibiotik sangat rendah. Hasil penelitian yang dilakukan WHO dari 12 negara termasuk Indonesia, sebanyak 53-62% berhenti minum antibiotik ketika merasa sudah sembuh. Resistensi antibiotik saat ini menjadi ancaman terbesar bagi kesehatan masyarakat global, sehingga WHO mengkoordinasi kampanye global untuk meningkatkan kesadaran dan perilaku masyarakat terhadap antibiotik. Metode Yang digunakan adalah memberikan penyuluhan Sosialisasi Penggunaan Antibiotik dan Efek Penyalahgunaan Antibiotik Guna Pengendalian Resistensi Antibiotik di Desa Sanrobone Kecamatan Sanrobone Kabupaten Takalar Sulawesi Selatan. Target luaran untuk enambah pengetahuan dan pemahaman masyarakat mengenai Penggunaan Antibiotik dan Efek Penyalahgunaan Antibiotik, memberikan bahan ajar seperti banner, poster, leaflet bergambar yang mudah dimengerti dan dapat dipergunakan setelah kegiatan ini. Berdasarkar dari data hasil kuesioner (pre dan post test) pada peserta, didapatkan peningkatan pemahaman tentang Penggunaan Antibiotik dan Efek Penyalahgunaan Antibiotik Guna Pengendalian Resistensi Antibiotik. Dimana jumlah jawaban benar meningkat pada hasil pre-test (evaluasi). Dari hasil evaluasi tersebut, kami tim pengabdian kepada masyarakat menyimpulkan keberhasilan kegiatan ini, dimana masyarakat jadi lebih mengetahui apa itu antibiotik, bagaimana penggunaannya sehingga tidak menimbulkan resistensi dikemudan hari.
РЕЗУЛЬТАТИ ДОСЛІДНО-ЕКСПЕРИМЕНТАЛЬНОЇ РОБОТИ ЩОДО ФОРМУВАННЯ ПАТРІОТИЗМУ ВІЙСЬКОВОСЛУЖБОВЦІВ
Authors: Каменюк Ю.
Published: March 2021

У статті розглядається проблема формування патріотизму у курсантів вищих військових навчальних закладів. Здійснено опис експерименту, що проводився з курсантами Військового інституту Київського Національного університету імені Тараса Шевченка. Подано результати дослідно-експериментальної роботи щодо формування патріотизму військовослужбовців та наведено їх інтерпретацію.

Ключові слова: патріотизм; дослідно-експериментальна робота; курсант; експеримент; експериментальна група, контрольна група.
ПРО ВЗАЄМОЗВ`ЯЗОК МІЖ ОСОБИСТІСНОЮ ТРИВОЖНІСТЮ І ПРОФЕСІЙНОЮ АДАПТАЦІЄЮ МАЙБУТНІХ ПЕДАГОГІВ В ПРОЦЕСІ НАВЧАННЯ У ЗАКЛАДІ ВИЩОЇ ОСВІТИ
Authors: Козак О.
Published: March 2021

У статті зазначається, що порядок термінальних цінностей майбутніх педагогів спрямований на зниження ними тривоги і компенсацію почуття власної неповноцінності, а комбінація інструментальних цінностей демонструє орієнтири у побудові майбутніми педагогами найбільш ефективних форм їхньої поведінки.

Ключові слова: особистісна тривожність; майбутні педагоги; професійна адаптація; заклад вищої освіти; термінальні цінності; інструментальні цінності.
ТЕОРЕТИЧНІ ЗАСАДИ РОЗРОБЛЕННЯ КАЛІФОРНІЙСЬКОГО ПСИХОЛОГІЧНОГО ОПИТУВАЛЬНИКА
Authors: Барко В.І. , Барко В.В. , Бондаренко В.
Published: March 2021

Стаття присвячена дослідженню теоретичних підходів до розроблення Каліфорнійського психологічного опитувальника – поширеного в англомовних країнах психодіагностичного інструменту, який з 50-х років минулого століття використовується психологами з метою професійного добору і психологічного супроводу персоналу багатьох організацій, у тому числі правоохоронних органів. У статті розкрито теоретичне підгрунтя Каліфорнійського психологічного опитувальника, яке ґрунтується на ортогональній моделі взаємодії двох основних особистісних вимірів – інтроверсії та екстраверсії, а також інтернальності та екстернальності. Автори статті переконливо доводять доцільність здійснення українськомовної адаптації Каліфорнійського психологічного опитувальника з метою його використання в роботі з персоналом правоохоронних органів, оскільки опитувальник уможливлює комплексну психологічну діагностику низки важливих індивідуально-психологічних особливостей особи, включеними у чотири основні категорії, які пов’язані із: відносинами з іншими людьми; особливостями управління собою; особливостями мотивації і когнітивного стилю; особистісними характеристиками працівника.

Ключові слова: Каліфорнійський психологічний опитувальник; особистість; персонал, психодіагностика; професійний добір; здібності; мотивація.
ВПЛИВ МОТИВАЦІЇ НА ЕФЕКТИВНІСТЬ САМОПРЕЗЕНТАЦІЇ МАЙБУТНЬОГО ПСИХОЛОГА
Authors: Теслюк В. , Денисенко С.
Published: March 2021

У статті досліджується вплив мотивації на ефективність самопрезентації майбутнього психолога. Аналізуються наукові праці вчених щодо дослідження самопрезентації особистості. Описуються результати емпіричного дослідження мотивації до успіху і уникнення невдачі майбутніх психологів. Встановлено, що найбільший кореляційний зв’язок існує між рівнем ефективності самопрезентації і мотивацією до успіху. Кореляційний зв'язок між рівнем ефективності самопрезентації і мотивацією уникнення невдач практично відсутній.
关于5GCRAN机房一体化机柜的方案思路探讨
Authors: 杨 金国
Published: March 2021

随着5G传输网络建设规模逐渐增大，C-RAN网络部署加快，无线专业设备安装的快速增加，造成现有汇聚节点机房的空间、机位、电源资源均出现不同程度的紧张，影响5G的发展。面对这些问题，可以新建一些户外一体化智能恒温机房（四舱 体）作为C-RAN设备机房。
5G基站电源改造的解决方案分析
Authors: 宋 彦博
Published: March 2021

本篇文章基于目前5G网络已经进入实质性建设时期，新增网络设备系统会给基站的电源系统带来较大的压力。因此，现阶段需要给基站电源进行改造，以便能够满足5G网络建设的需求。
无人机倾斜摄影测量在城市建筑物竣工测量中的应用
Authors: 梁 怀标
Published: March 2021

无人机摄影测量技术在近年来得到迅速地发展，其在城市规划与建筑工程当中发挥着越来越重要的作用。无人机摄影测量是一种新技术的运用也是一种新的工作方法，其技术与方法也更加值得研究。本篇文章对无人机倾斜摄影测量在城市建筑物竣工测量中的应用进行简要的分析，从不同的切入点来探讨无人机倾斜测量的实际效果。
给水排水管道水平定向钻技术设计研究
Authors: 李 昌宏
Published: March 2021

随着城市化建设进程的推进，给水排水管道施工若遇到交通繁忙路段或河道等障碍物采取开挖方式，则会影响城市交通及河道景观等，阻碍城市正常运转，因此水平定向钻非开挖技术在给水排水管道工程中应用愈发广泛。基于此，文章首先阐述了水平定向钻技术在给水排水管道施工的技术优势，并对水平定向钻技术设计进行研究分析。
The Potential of 9,10-Anthraquinone in Inhibiting Human Cancer Cells Growth
Authors: Batubara Irmanida , Hakim Arif Rakhman , Mariya Silmi , Achmadi Suminar Setiati , Valentina Sokoastri Valentina Sokoastri , Mulyatni Agustin Sri , Suprihatini Rohayati
Published: March 2021

Background: 9,10-Anthraquinone (9,10-AQ) is a contaminant on some agricultural products and considered as carcinogenic based on EU Regulation No. 1146/2014. Except for little evidence on experimental rats, there is no strong proof regarding the carcinogenicity in humans. Therefore, it is essential to find a safe dose of this compound since the difference in 9,10-AQ levels will affect cancer cell growth. This research aims to find the 9,10-AQ concentration that does not proliferate the human cancer cells under in vitro study.Methods: In determining the 9,10-AQ concentration that does not proliferate the cancer cells growth, 0.01 to 500 mg/L 9,10-AQ was directly tested on four human cancer cells (colorectal carcinoma HCT 116, colon adenocarcinoma WiDr, breast cancer MCF-7, and cervical cancer HeLa), and the viability of the cells was counted via (3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl tetrazolium bromide) assay. In the gene expression level, the effects on a selected cancer cell line were determined by qRT-PCR against BAX, BCL-2, PCNA, and P53.Results: The result indicates that 9,10-AQ up to 500 mg/L concentration does not proliferate the cell’s growth but instead inhibits those four cancer cells’ growths. The concentration of 9,10-AQ that inhibits 50% the cancer cells growth (IC50) value was 321.8 mg/L (1.55 mM) against HCT 116 and above 500 mg/L (above 2.40 mM) against WiDr, MCF-7, and HeLa. The 9,10-AQ at 500 mg/L (or 2.40 mM) increases BAX expression and acts as an apoptotic agent on HeLa cells.Conclusions: The investigation has shown that 9,10-AQ up to 500 mg/L concentration does not proliferate the cancer cell growth; instead, it inhibits the HCT 116 and HeLa cells growth. We have preliminary evidence regarding the apoptotic mechanism of 9,10-AQ by increasing BAX gene expression on HeLa cells.
Cyclin D1 and Chemotherapy Response
Authors: Cahyanur Rahmat , Irawan Cosphiadi
Published: March 2021

Cyclin D1 is a protein that plays a role in the transition from the G1 to S phase of the cell cycle. Cyclin D1 expression has been found to increase in various malignancies and, in many studies, was associated with tumor growth, stage, lymph node involvement, distant metastases, and poor prognosis. Until now, studies on the association of cyclin D1 expression level with chemotherapy response have shown different results. An in-depth understanding of the cell cycle will allow doctors to develop target therapies that work when specific interventions are carried out at certain stages. Some studies reported that cyclin D1 expression was inversely related to chemotherapy response, while others showed opposite results. A significant number of studies have attempted to elucidate this ambiguous effect of cyclin D1. The suggested mechanism involves the difference of cancer cell types, the effect of chromosome instability in a few malignancies, trigger to an excessive DNA repair protein expression stimulus, and the response to DNA damage severity. The ambiguous effect of cyclin D1 towards chemotherapy was thought to arise from the difference in tumor type, chemotherapy agents used, and cell damage severity caused by cytostatics as per different research works. More in-depth research with parallel evaluation of other possible mechanisms such as DNA repair should elucidate the reason behind the inconsistent findings.
Determinants of Human Papilloma Virus (HPV) Vaccination among Elementary Students in Central Jakarta
Authors: Wahidin Mugi , Febrianti Rini
Published: March 2021

Background: Human Papilloma Virus (HPV) is the leading risk factor of cervical cancer. World Health Organization (WHO) has recommended including HPV vaccination in national immunization programs in all countries. Specifically, Jakarta Province has been implementing HPV vaccination since 2016. In this case, several factors influence vaccination coverage. However, there is limited evidence about determinants associated with HPV vaccination. Therefore, this study aimed to investigate the factors associated with HPV vaccination among elementary students in Central Jakarta.Methods: This was a cross-sectional study conducted from March until June 2020. The study population involved 167 female students of the 6th level of the elementary school in Central Jakarta. There were eight elementary schools in Kemayoran and Cempaka Putih Sub Districts selected purposively. Primary data was collected employing an online questionnaire, which was fulfilled by respondents (mothers and students). Data were analyzed utilizing statistic software for descriptive and bivariate analysis. For the bivariate analysis, Chi-Square Test was performed.Results: The HPV vaccination coverage was 80.84%. It was also showed that the last education level of the respondents’ father and mother was mainly senior high school (SMA) for 50.3% and 47.9%, respectively. The mothers’ knowledge was mainly in the middle (56.9%), and they had a positive attitude/support (67.1%). There were only 2.4% of the respondents with a family history of cervical cancer. In terms of family economic status, the main part of respondents had low expenditure for 2-3 million IDR (59.3%) a month. Meanwhile, human resources (vaccination providers) and HPV vaccine were 100% available in the vaccination service. Of the respondent, 47.9% of those said that the vaccine price was affordable. Children who had no support to get HPV vaccination from their father, mother, and siblings were 14.4%, 6.6%, and 21.6%, respectively. Besides, children who were not supported by their teachers was 3.6% and not supported by their peers was 23.4%. Meanwhile, father and mother’s supports were significantly associated with HPV vaccination.Conclusions: Factors associated with HPV vaccination were the support from the father and mother.
The Effect of Stakeholder’s Pressure on Firm Performance and the Moderating Role of Perceived Economic Crisis
Authors: Mousavi Mir Damoun , Mousavi Mir Danial
Published: March 2021

The stakeholder pressure is one of the institutional pressures, in this regard, organizations have their internal characteristics to match the expectations of key stakeholders in the environment. In the present study, the effect of stakeholder’s pressure on firm performance was examined considering the moderating role of the perceived economic crisis. To investigate relationships, 208 questionnaires were collected from firms listed in the Tehran stock exchange. Structural equation modeling and PLS software were used to investigate the relationships. The results of this study showed that stakeholder’s pressure has a positive effect on firm performance, and perceived economic crisis reduces firm performance, and when firms believe to more likely to be in crisis, the positive effect of stakeholder’s pressure on firm performance was decreased.
MiR-133a-3p Relieves the Oxidative Stress Induced Trophoblast Cell Apoptosis Through the BACH1/Nrf2/HO-1 Signaling Pathway
Authors: GUO H , WANG Y , JIA W , LIU L
Published: March 2021

Preeclampsia (PE) is a major cause of the pregnancy morbidity and mortality over the world. Disorganized placentation caused by trophoblast cell abnormity is one of main risk factors to induce PE. MiR-133a-3p has been shown to contain regulatory effects on oxidative stress in the cardiomyocytes. But the effects of
miR-133a-3p on oxidative stress-induced apoptosis in the trophoblast cells remain unknown. In this study, trophoblast HTR-8/SVneo cells were transfected with miR-133a-3p mimics and inhibitor. H2O2 (250 μM) treatment of cells was adopted to induce oxidative stress. A series of typical molecular and cellular experiments was subsequently performed in order to investigate this issue. It was found that miR-133a-3p overexpression attenuated the oxidative stress induced by H2O2 through reduced ROS and MDA levels and enhanced antioxidase activities in the trophoblast cells. Overexpressed miR-133a-3p was shown to relieve the oxidative stress-induced apoptosis of HTR-8/SVneo cells. At molecular levels, a direct binding effect of miR-133a-3p on BACH1 was verified. Moreover, miR-133a-3p overexpression also enhanced BACH1 downstream Nrf2/HO-1 signaling to activate antioxidant genes. It is collectively demonstrated that miR-133a-3p can relieve the oxidative stress-induced apoptosis in the trophoblast cells through the BACH1/Nrf2/HO-1 signaling pathway via targeting BACH1 directly. This regulatory mechanism of miR-133a-3p in the trophoblast cells under oxidative stress may give a new perspective for oxidative stress-induced trophoblast cell abnormality and be useful to study more pathological mechanisms of PE.
SHEVCHENKO’S SIGNIFICANCE FOR SHAPING THE NATIONAL IDENTITY OF THE UKRAINIAN POST-SIXTIERS GENERATION IN THE RUSSIAN EMPIRE OF THE 19TH CENTURY
Authors: Kharchuk Roksana
Published: March 2021

The paper deals with the perception of Shevchenko’s poetry by the generation of post-1860s Ukrainians in the Russian Empire excluding S. Yefremov and O. Lototskyi whose stories have been addressed in a separate study. Based on memoirs, diaries, and correspondence, the author concludes about the influence of the poet’s work on T. Zinkivskyi, M. Slavinskyi, P. Tuchapskyi, Ye. Chykalenko, B. Hrinchenko, M. Hrushevskyi, and D. Doroshenko. They all had “Kobzar” among their books, while the perception of Shevchenko’s works by them was not identical. For T. Zinkivskyi, M. Slavinskyi, and B. Hrinchenko the poet formed the foundation of their own creativity; M. Hrushevskyi deepened his knowledge of Shevchenko’s work under the influence of О. Konyskyi; D. Doroshenko became interested in Shevchenko’s poetry still in childhood. Ye. Chykalenko considered Shevchenko’s work to be insufficiently developed, as well as М. Drahomanov. P. Tuchapsky adapted Shevchenko to socialism. Not everyone was impressed by “Kobzar” as a child due to difficulties in perceiving Shevchenko’s poetry at an early age. The very access to his works, especially uncensored, was also limited in Russia, but as an adult, each intellectual of the post-sixtiers (except P. Tuchapskyi) recognized Shevchenko’s influence on the formation of his own national identity. Although the generation of the post-sixtiers was focused mainly on politics rather than cultural work and their circle of reading was broader than the one of their predecessors, Shevchenko did not lose his signficance for them either. The post-1860s generation also understood the need for scholarly studies on Shevchenko’s works; in particular, V. Domanytskyi critically examined the poet’s texts.
ADDRESSING STRATEGIES IN THE TEXTS OF SHEVCHENKO-STORYTELLER
Authors: Smilanska Valeriia
Published: March 2021

The paper considers the metanarrative (exegetical) and metanarrative (exegetical) and metafictional (diegetical) aspects of a work, the ways of the author’s contacts with the reader/listener. The nature of addressing may be direct, which implies the explicit addressee, and hidden, designed for the implicit addressee. The latter is present as an ideal recipient who perceives the aesthetic mode of the work. The strategy of intimate connection with the reader is based on the ascending evaluative direction, while the descending one serves as a basis for the discrediting strategy, realized in a number of communicative tactics, used by the narrators-addressers. The images of the narrator and storytellers perform different functions (hero, character-witness); the narrative composition of each story is not repeated in other works, gradually becoming more complicated. The author uses various compositional and verbal forms: in addition to a consistent story and narrative, description and reflection, he involves the forms of inserted narrative, epistolary text, and even a full-length story of an eyewitness. Tactics of oral communication and its constitutive stylistic features are presented by D. Barannyk as Shevchenko’s version of Ukrainian oral narrative, open to the addressee, and as a means of involving the reader in the imaginary world of a work. The term ‘self-presentation’ as an action of informing the addressee about the narrator’s occupation and his social status in order to establish contact differs from ‘self-thematization’ which is an intimate self-characterization of the narrator, addressed to a friendly reader/listener. The latter also includes the digressive reflections of the narrator on moralistic, sociological, historical, artistic topics, which reveal his mentality.
FLANEUR’S ANXIOUS MASCULINITY: A COMPARATIVE ANALYSIS OF THE NOVELS “MIST” BY M. DE UNAMUNO AND “NOTES OF SNUB-NOSED MEPHISTOPHELES” BY V. VYNNYCHENKO
Authors: Tyshchenko Anastasia
Published: March 2021

At the beginning of the 20th century, modernist literature starts to face the new existential issues unfolded in the urban environment. One of these issues is the phenomenon of anxious masculinity caused by the destruction of the patriarchal paradigm.

In the literatures that were moving from the traditional type of culture to urban and modern, the writers described men who went out on the streets, converting themselves into the urban cultural type known as flânerie. The practice of ﾠflânerie, first presented in French literature, became popular in other European literatures as well, Spanish and Ukrainian not being exceptions. However, the type of flâneur in these two literatures still requires a scrupulous study.

The paper provides a comparative analysis of M. de Unamuno’s “Niebla” (“Mist”) and V. Vynnychenko’s “Zapysky kyrpatoho Mefistofelia” (“Notes of Snub-Nosed Mephistopheles”) aiming to analyze the represented types of flâneurs. The novels demonstrate the specifics of flâneur’s discourse in Spanish and Ukrainian literatures, which were undergoing modernization processes. The comparison of such elements as writers’ urban experiences, protagonists’ interaction with the urban space, meeting with the modern women on the streets as the main plot element, and gender issues allowed defining different reflections on anxious masculinity and broadening European ﾠflânerie discourse. In addition, the analysis defined the protagonists of the novels as proto-ﾠ вneurs, which creates the perspective for further studies of the ﾠflânerie in Spanish and Ukrainian literatures.

The results of the research provide arguments for the hypothesis that the ﾠflânerie is one of the modernist perception strategies, symptomatic for European culture.
Блочная структура периодичности и прогнозирование новых химических элементов
Authors: ГУСЕВ Борис Владимирович , ИН Самуэл Иен-Лян , СПЕРАНСКИЙ Анатолий Алексеевич
Published: March 2021

В статье представлен прогноз существования новых химических элементов по сравнению с периодической системой Д. И. Менделеева. Для прогнозирования используется метод структурного порядкового анализа и анализируется модель строения энергетических уровней и подуровней (орбиталей). Сформулированы новые представления о блочности в Периодической системе химических элементов, а также получены граничные элементы с завершенным строением энергетических уровней в пределах каждого блока и их четкое расположение. Представленные результаты подтверждаются соотношением протонов и нейтронов в ядрах элементов для каждого блока, в том числе для новых, еще экспериментально не полученных химических элементов. Использование объемной матрицы химических элементов позволит получить математическое описание структуры периодической системы, разработать цифровые модели взаимодействия элементов между собой, что даст возможность прогнозировать создание новых молекул и получать новые материалы.
Effectiveness of Individual Performance Dialogue on Employee Performance (Case Studies on Civil Servants of the Ministry of Finance in City of Semarang)
Authors: Sudiarti Ni Made Watimena , Noersasongko Edi , Pramudi Yuventius Tyas Catur
Published: March 2021

Bureaucratic Reform in human resources began with the birth of Law No. 5 of 2014 on State Civil Apparatus (ASN). The new paradigm in the ASN Law makes ASN employees a profession that has an obligation to conduct self-development and must take responsibility for performance and apply merit principles in the implementation of ASN management. The Ministry of Finance followed up the Bureaucratic Reform in hr with performance management policies. Performance management in the Environment of the Ministry of Finance consists of three main stages, namely planning, monitoring, and determining performance results and evaluation.  Performance evaluation results determine the performance value of employees and organizations, which affects employee careers and compensation. The solution by the Ministry of Finance is to implement management practices called Organizational Performance Dialogue (DKO) and Individual Performance Dialogue (DKI) whose main purpose is to improve the performance of employees and organization. This research is explanatory, where the research method used is Partial Least Square (PLS), with software for analysis using SmartPLS. Data collection instruments using questionnaires and structured interviews with research respondents are employees of the Ministry of Finance in Semarang City area. This research aims to know the effectiveness of performance dialogue on employee performance, so that the results are expected to be a reference in management practices in organizational units in the environment of the Ministry of Finance in an effort to improve the performance of employees and organizations. Keywords:Effectiveness, Individual factors, Leadership factors, Performance dialogue, Employee performance
Strategies for Teaching Undergraduate Business Students Data Analytics
Authors: Atkinson J. Kirk , Blankenship Ray , Crawford Brady , Ramage Tucker S.
Published: March 2021

Several class sections at a Midwestern, public university were instructed in basic data analytics concepts using SimNet® preparatory assignments with Microsoft Excel®, additional instructional materials, and subsequent analytics projects. Performance on each analytics project was measured against performance on the preparatory Excel assignments as well as the student final course performance. The preparatory assignments prepared students for associated analytics projects as well as the final assessment.
The Psychoanalyst, Caught Between Interior and Exterior Reality
Authors: Becker Hans , Becker Sophinette
Published: March 2021

The psychoanalyst, caught between inner and outer reality. The authors consider under what conditions reference to external reality impedes or furthers the analytic process.
Faith and the Family: Family Life and the Spread of Evangelical Culture in the Scottish Gàidhealtachd, c. 1790–c. 1860
Authors: Ritchie Elizabeth
Published: March 2021

This examination of the Scottish Gàidhealtachd (Gaelic-speaking area) extends beyond protestant ideas about the gendered family to how people actually implemented spiritual practices at home. The results complicate earlier conclusions, showing that family worship undermined as well as reinforced the patriarchal family. The challenge to fathers’ authority came less from the influence of mothers than from children and non-family members who, through literacy, became better equipped than fathers for spiritual leadership. Examining family life shows how some Gaels used evangelicalism to reshape their culture while also exposing how others resisted this change.
Dounreay: Creating the Nuclear North
Authors: Ross Linda M.
Published: March 2021

This article combines the traditionally rural focus of Highland history with the growing field of nuclear culture to examine the impact which Dounreay Experimental Research Establishment had on Caithness between 1953 and 1966. From the outset of the project the United Kingdom Atomic Energy Authority knew that it would have to import specialist technical staff into an area economically driven by agriculture and fishing. This resulted in a distinct form of employment-based migration to the Highlands, reversing population decline in Caithness during the period of study. This article identifies the reasons for, and local reaction to, the UKAEA's choice of Caithness as the location for its fast breeder reactor establishment. It assesses the significant in-migration to the area during the initial phase of the Dounreay plant's development, before exploring how perceptions of distance and Caithnessian ‘difference’ affected the recruitment of staff in what the UKAEA considered an ‘unconventional’ location. It puts people and place at the centre of the nuclear project, revealing Dounreay's role in creating a mid-twentieth century Highland counter-narrative of in-migration and modernity far removed from traditional discourses of depopulation.
THE EFFECTS OF ORGANIZATIONAL CULTURE ON EMPLOYEE PERFORMANCE IN SUMEDANG SELATAN DISTRICT OFFICE SUMEDANG REGENCY
Authors: Febianti Fepi , Nurwan Teddy Marliadi
Published: March 2021

The core of the problem in this study is to determine the effects of organizational culture on employee performance in Sumedang Selatan District Office, Sumedang Regency. This study aims to determine the implementation, correlation, and effects of organizational culture on employee performance in Sumedang Selatan District Office, Sumedang Regency. This study used a survey method. Data collection techniques used were observation, interviews, questionnaires, and data processing related to the problems studied namely organizational culture and employee performance. The analysis technique used is a simple regression analysis, correlation test, coefficient of determination, and hypothesis testing. The research sample used as many as 46 people, namely all civil servants in Sumedang Selatan District Office. The results of quantitative calculations were obtained based on the value of the Pearson correlation (r). It is known that the r value for the effects of organizational culture (X) on employee performance (Y) is 0.713 r table 0.290. So it can be concluded that there is a correlation between the organizational culture (X) to employee performance (Y).
Antibacterial Albumin-Tannic Acid Coatings for Scaffold-Guided Breast Reconstruction
Authors: Cometta Silvia , Bock Nathalie , Suresh Sinduja , Dargaville Tim R. , Hutmacher Dietmar W.
Published: March 2021

Infection is the major cause of morbidity after breast implant surgery. Biodegradable medical-grade polycaprolactone (mPCL) scaffolds designed and rooted in evidence-based research offer a promising alternative to overcome the limitations of routinely used silicone implants for breast reconstruction. Nevertheless, as with any implant, biodegradable scaffolds are susceptible to bacterial infection too, especially as bacteria can rapidly colonize the biomaterial surface and form biofilms. Biofilm-related infections are notoriously challenging to treat and can lead to chronic infection and persisting inflammation of surrounding tissue. To date, no clinical solution that allows to efficiently prevent bacterial infection while promoting correct implant integration, has been developed. In this study, we demonstrated for the first time, to our knowledge that the physical immobilization of 1 and 5% human serum albumin (HSA) onto the surface of 3D printed macro- and microporous mPCL scaffolds, resulted in a reduction of Staphylococcus aureus colonization by 71.7 ± 13.6% and 54.3 ± 12.8%, respectively. Notably, when treatment of scaffolds with HSA was followed by tannic acid (TA) crosslinking/stabilization, uniform and stable coatings with improved antibacterial activity were obtained. The HSA/TA-coated scaffolds were shown to be stable when incubated at physiological conditions in cell culture media for 7 days. Moreover, they were capable of inhibiting the growth of S. aureus and Pseudomonas aeruginosa, two most commonly found bacteria in breast implant infections. Most importantly, 1%HSA/10%TA- and 5%HSA/1%TA-coated scaffolds were able to reduce S. aureus colonization on the mPCL surface, by 99.8 ± 0.1% and 98.8 ± 0.6%, respectively, in comparison to the non-coated control specimens. This system offers a new biomaterial strategy to effectively translate the prevention of biofilm-related infections on implant surfaces without relying on the use of prophylactic antibiotic treatment.
Protease Nexin-1 in the Cardiovascular System: Wherefore Art Thou?
Authors: Madjene Celina , Boutigny Alexandre , Bouton Marie-Christine , Arocas Veronique , Richard Benjamin
Published: March 2021

The balance between proteases and protease inhibitors plays a critical role in tissue remodeling during cardiovascular diseases. Different serine protease inhibitors termed serpins, which are expressed in the cardiovascular system, can exert a fine-tuned regulation of protease activities. Among them, protease nexin-1 (PN-1, encoded bySERPINE2) is a very powerful thrombin inhibitor and can also inactivate plasminogen activators and plasmin. Studies have shown that this serpin is expressed by all cell subpopulations in the vascular wall and by circulating cells but is barely detectable in plasma in the free form. PN-1 present in platelet granules and released upon activation has been shown to present strong antithrombotic and antifibrinolytic properties. PN-1 has a broad spectrum of action related to both hemostatic and blood vessel wall protease activities. Different studies showed that PN-1 is not only an important protector of vascular cells against protease activities but also a significant actor in the clearance of the complexes it forms with its targets. In this context, PN-1 overexpression has been observed in the pathophysiology of thoracic aortic aneurysms (TAA) and during the development of atherosclerosis in humans. Similarly, in the heart, PN-1 has been shown to be overexpressed in a mouse model of heart failure and to be involved in cardiac fibrosis. Overall, PN-1 appears to serve as a “hand brake” for protease activities during cardiovascular remodeling. This review will thus highlight the role of PN-1 in the cardiovascular system and deliver a comprehensive assessment of its position among serpins.
A Meta-Analysis of Ten Learning Techniques
Authors: Donoghue Gregory M. , Hattie John A. C.
Published: March 2021

This article outlines a meta-analysis of the 10 learning techniques identified in Dunlosky et al. (2013a), and is based on 242 studies, 1,619 effects, 169,179 unique participants, with an overall mean of 0.56. The most effective techniques are Distributed Practice and Practice Testing and the least effective (but still with relatively high effects) are Underlining and Summarization. A major limitation was that the majority of studies in the meta-analysis were based on surface or factual outcomes, and there is caution needed when applying these findings to deeper and more relational outcomes. Other important moderators included the presence of feedback or not, near or far transfer, and the effects were much greater for lower than higher ability students. It is recommended that more attention be paid to when, under what conditions, each technique can be used, and how they can best be taught.
Obesity and Dietary Added Sugar Interact to Affect Postprandial GLP-1 and Its Relationship to Striatal Responses to Food Cues and Feeding Behavior
Authors: Jones Sabrina , Luo Shan , Dorton Hilary M. , Yunker Alexandra G. , Angelo Brendan , Defendis Alexis , Monterosso John R. , Page Kathleen A.
Published: March 2021

It has been hypothesized that the incretin hormone, glucagon-like peptide-1 (GLP-1), decreases overeating by influencing mesolimbic brain regions that process food-cues, including the dorsal striatum. We previously showed that habitual added sugar intake was associated with lower glucose-induced circulating GLP-1 and a greater striatal response to high calorie food cues in lean individuals. Less is known about how dietary added sugar and obesity may interact to affect postprandial GLP-1 and its relationship to striatal responses to food cues and feeding behavior. The current study aimed to expand upon previous research by assessing how circulating GLP-1 and striatal food cue reactivity are affected by acute glucose consumption in participants with varied BMIs and amounts of habitual consumption of added sugar. This analysis included 72 participants from the Brain Response to Sugar Study who completed two study visits where they consumed either plain water or 75g glucose dissolved in water (order randomized; both drinks were flavored with non-caloric cherry flavoring) and underwent repeated blood sampling, a functional magnetic resonance imaging (fMRI) based food-cue task, and an ad-libitum buffet meal. Correlations between circulating GLP-1 levels, striatal food-cue reactivity, and food intake were assessed, and interactions between obesity and added sugar on GLP-1 and striatal responses were examined. An interaction between BMI and dietary added sugar was associated with reduced post-glucose GLP-1 secretion. Participants who were obese and consumed high levels of added sugar had the smallest increase in plasma GLP-1 levels. Glucose-induced GLP-1 secretion was correlated with lower dorsal striatal reactivity to high-calorie versus low-calorie food-cues, driven by an increase in reactivity to low calorie food-cues. The increase in dorsal striatal reactivity to low calorie food-cues was negatively correlated with sugar consumed at the buffet. These findings suggest that an interaction between obesity and dietary added sugar intake is associated with additive reductions in postprandial GLP-1 secretion. Additionally, the results suggest that changes to dorsal striatal food cue reactivity through a combination of dietary added sugar and obesity may affect food consumption.
SWEET Transporters and the Potential Functions of These Sequences in Tea (Camellia sinensis)
Authors: Jiang Lan , Song Cheng , Zhu Xi , Yang Jianke
Published: March 2021

Tea (Camellia sinensis) is an important economic beverage crop. Its flowers and leaves could be used as healthcare tea for its medicinal value. SWEET proteins were recently identified in plants as sugar transporters, which participate in diverse physiological processes, including pathogen nutrition, seed filling, nectar secretion, and phloem loading. Although SWEET genes have been characterized and identified in model plants, such as Arabidopsis thaliana and Oryza sativa, there is very little knowledge of these genes in C. sinensis. In this study, 28 CsSWEETs were identified in C. sinensis and further phylogenetically divided into four subfamilies with A. thaliana. These identified CsSWEETs contained seven transmembrane helixes (TMHs) which were generated by an ancestral three-TMH unit with an internal duplication experience. Microsynteny analysis revealed that the large-scale duplication events were the main driving forces for members from CsSWEET family expansion in C. sinensis. The expression profiles of the 28 CsSWEETs revealed that some genes were highly expressed in reproductive tissues. Among them, CsSWEET1a might play crucial roles in the efflux of sucrose, and CsSWEET17b could control fructose content as a hexose transporter in C. sinensis. Remarkably, CsSWEET12 and CsSWEET17c were specifically expressed in flowers, indicating that these two genes might be involved in sugar transport during flower development. The expression patterns of all CsSWEETs were differentially regulated under cold and drought treatments. This work provided a systematic understanding of the members from the CsSWEET gene family, which would be helpful for further functional studies of CsSWEETs in C. sinensis.
Interrelationship of Stress, Environment, and Herpes Simplex Virus Type-1 on Behçet’s Disease: Using a Mouse Model
Authors: Islam S. M. Shamsul , Ryu Hye-Myung , Sayeed Hasan M. , Sohn Seonghyang
Published: March 2021

The purpose of this study was to investigate effects of stress and environment factors on the induction of Behçet’s disease (BD) using HSV-1 infected mouse model. BD is a chronic multisystemic inflammatory disease of unknown etiology. Environmental factors, immune dysfunction, and herpes simplex virus type-1 (HSV) infection might be triggers of BD. To investigate effects of environmental factors on the incidence of BD, HSV was inoculated into mice. Mice were then maintained in conventional facility or SPF facility to compare BD incidence rates. The incidence of BD was also tracked by adding stressors such as substance P (anxiety stress), 4°C (cold stress), xanthine sodium salt (oxidative stress), or 77 dB noise (noise stress). To clarify immune mechanisms involved in the difference in BD incidence caused by various stresses, dendritic cell activation markers were analyzed using flow cytometry. The combination of conventional environment, noise stress, and HSV had the highest rate of BD (38.1%) among all groups. However, HSV inoculated group in a SPF environment had the lowest incidence (2.2%). Frequencies of dendritic cell activation markers such as CD40, CD83, CD80, and CD86 were expressed differently under various stresses. Noise stress increased frequencies of CD83 positive cells. Noise stress also upregulated transcription factors T-bet and ROR-γt. Different gut microbiota compositions were observed between SPF and conventional environment by 16S rRNA sequence analysis. Environment and stress influenced the incidence of HSV-induced BD. Microbial diversity due to environmental differences might be one explanation for regional differences in the incidence of BD.
Risk of Stroke in Systemic Necrotizing Vasculitis: A Nationwide Study Using the National Claims Database
Authors: Ahn Sung Soo , Han Minkyung , Yoo Juyoung , Park Yong-Beom , Jung Inkyung , Lee Sang-Won
Published: March 2021

Objective

Evidences indicate that the risk of stroke is increased in autoimmune rheumatic diseases. This study aimed to investigate the incidence of stroke in patients with systemic necrotizing vasculitis (SNV) using the national health database.

Methods

Data were obtained from the Korean National Claims database between 2010 and 2018 to identify incident SNV [anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV) and polyarteritis nodosa (PAN)] cases. The standardized incidence ratio (SIR) and incidence rate ratio (IRR) were calculated to estimate the risk of stroke in patients with SNV compared to the general population and among disease subgroups. Time-dependent Cox’s regression analysis was performed to identify risk factors for stroke.

Results

Among 2644 incident SNV cases, 159 patients (6.0%) were affected by stroke. The overall risk of stroke was significantly higher in patients with SNV compared to the general population (SIR 8.42). Stroke event rates were the highest within the first year of SNV diagnosis (67.3%). Among disease subgroups, patients with microscopic polyangiitis (MPA) exhibited higher IRR compared to PAN (adjusted IRR 1.98). In Cox’s hazard analysis, older age and MPA were associated with higher risk of stroke [hazard ratio (HR) 1.05 and 1.88], whereas the administration of cyclophosphamide, azathioprine/mizoribine, methotrexate, and statins were protective in stroke (HR 0.26, 0.34, 0.49, and 0.50, respectively).

Conclusion

A considerable number of SNV patients experienced stroke, especially in the early phase of disease. Older age and MPA diagnosis were associated with elevated risk of stroke, while the administration of immunosuppressive agents and statins was beneficial in preventing stroke.