bluuebunny/crossref_metadata_2025 huggingface dataset:
DETEKSI DINI RISIKO GIZI KURANG PADA ANAK BALITA DENGAN DIARE MENGGUNAKAN METODE PYMS dan STRONGkidz
Authors: Hapsari Vike Dwi , Purwaty Nyimas Heny , Sulastri Titi
Published: November 2021

Diare menyebabkan berkurangnya nafsu makan dan gangguan yang mengakibatkan menurunnya absorbsi zat-zat nutrisi dalam tubuh sehinggamenimbulkan gizi kurang. Deteksi dini terhadap risiko gizi kurang salah satunya melakukan skrining gizi. Skrining gizi untuk anak diantara lain Paediatric Yorkhill Malnutrition Score (PYMS) danThe Screening Tool For Risk Of Impaired Nutrition Status and Growth (STRONG KIDZ). Tujuan penelitian adalah mengidentifikasi efektifitas PYMS dan STRONGKIDZ untuk deteksi dini risiko gizi kurang pada anak balita dengan diare. Metode penelitian ini menggunakan uji diagnostik desain cross sectional dan jumlah sampel 40 responden dengan pengambilan sampel teknik purposive sampling. Hasil sensitifitas dan spesifisitas skrining PYMS  sebesar 83,87% dan 88,88% dan hasil Strongkidz sebesar 46,42% dan 50%, dapat disimpulkan nilai PYMS lebih tinggi dibandingkan Strongkidz dengan nilai AUC PYMS sebesar 86% termasuk kategori baik, maka PYMS dapat dijadikan referensi dalam melakukan skrining untuk mendeteksi risiko gizi kurang pada anak balita dengan diare.
PERBEDAAN HEMOGLOBIN REMAJA PUTRI YANG MENDAPATKAN DENGAN YANG TIDAK MENDAPATKAN TABLET TAMBAH DARAH PEMERINTAH
Authors: Septiasari Yeti
Published: November 2021

Perbedaan Hemoglobin Remaja Putri Yang Mendapatkan Dengan Yang Tidak Mendapatkan Tablet Tambah Darah Pemerintah Kabupaten Pringsewu saat ini telah menjalankan program PPAGB untuk menanggulangi anemia pada remaja. Salah satu Puskesmas yang menjalankannya adalah Puskesmas Ambarawa. Tujuan penelitian ini adalah mengetahui Perbedaan Kadar Hemoglobin Pada Remaja Putri Yang Mendapatkan Tablet Tambah Darah Pemerintah Di SMA Wilayah Kerja  Puskesmas Ambarawa. penelitian ini peneliti menggunakan metode observasional analitik dengan pendekatan cross sectional. Penelitian ini memiliki dua variabel  independen (bebas) yaitu perbedaan kadar hemoglobin remaja putri yang di SMA Ambarawa  yang mendapat TTD Pemerintah dan yang tidak mendapatkan TTD Pemerintah di SMA Ambarawa. Jadi total sampel adalah 50 orang. Metode sampling yang digunakan adalah random sampling. instrument pengukuran kadar hemoglobin dengan menggunakan rapid test. Analisis data menggunakan uji T-test independent tidak berpasangan dengan tingkat kepercayaan 95%. Hasil penelitian didapatkan remaja yang rutin mendapatkan tablet fe sebanyak 52%. Rata-rata kadar hemoglobin pada remaja yang mendapatkan suplementasi fe adalah 11,5(1,79) gr/dl. rata-rata kadar hemoglobin pada remaja yang mendapatkan suplementasi fe adalah 11,5(1,79) gr/dl. Didapatkan nilai Mean Difference sebesar -0,2298,  Hasil uji statistik didapatkan p value 0,657. Hal ini berarti Ho diterima dan Ha ditolak sehingga dapat disimpulkan tidak ada perbedaan Kadar Hemoglobin remaja putri yang mendapatkan program intervensi suplementasi Fe dengan yang tidak mendapatkan suplementasi fe di SMA wilayah kerja Puskesmas Ambarawa
Family Planning Knowledge and Practices in Two Communities in Lagos State, Nigeria
Authors:   Department of Clinical Pharmacy & Biopharmacy, Faculty of Pharmacy, University of Lagos, Nigeria, Okoye N.V. , Gbemisola A. ,   Department of Clinical Pharmacy & Biopharmacy, Faculty of Pharmacy, University of Lagos, Nigeria
Published: November 2021

Background: Family planning (FP) refers to use of birth control methods that allow a couple to control their family size. Research shows that peoples’ quality of life improves when they are able to decide the number and spacing of their children and there are various methods available to help people achieve this purpose. Objectives: The aim of this study was to determine respondents’ knowledge and practice about FP and their most utilized and best methods. Methods: Pretested, semi-structured questionnaires were administered to 100 residents each in two communities (Mushin and Ojo) in Lagos after informed consent was obtained. The locations were conveniently selected. Data were analysed by descriptive and inferential statistics using Microsoft-Excel and Statistical Package for the Social Sciences (SPSS). Results obtained were presented as tables and charts. Results: Demographic profiles show that majority were females (90.2%) and were 45 years and below (77.2%). About 72% of the respondents use contraceptive methods. The results show that the respondents have a good knowledge of FP and use is high. The most known methods are the male condom (100.0%) and calendar/rhythm (92.9%) while the most utilized methods are emergency contraception (45.9%) and male-condom (40.7%). The most preferred methods according to the respondents are the male condom (27.1%) and abstinence (26.9%). Conclusion: Awareness of FP and contraceptive use rate was high in the two communities. Routine use of emergency contraception was recorded. The study recommends public enlightenment campaigns to further improve the knowledge and correct those misconceptions that exist.
Influence of patient’s knowledge of hypertension and beliefs about medicines on adherence in Lagos University Teaching Hospital (LUTH), Lagos
Authors:   Department of Clinical Pharmacy and Biopharmacy, Faculty of Pharmacy, University of Lagos, Lagos, Nigeria, Olugbake O.A. , Odugbemi O.T. ,   Department of Clinical Pharmacy and Biopharmacy, Faculty of Pharmacy, University of Lagos, Lagos, Nigeria
Published: November 2021

Background: Poor adherence to antihypertensive medications compromises the effectiveness of treatment outcomes and has been associated with increased morbidity and mortality. An understanding of beliefs to hypertensive medicines may result in better understanding and improvement of non-adherence among patients. Objective: This study was carried out to assess the knowledge and beliefs to hypertensive drugs among out-patients in the Lagos University Teaching Hospital. Methods: Hypertensive out-patients attending the clinic of Lagos University Teaching Hospital, Idi-araba, Lagos, were approached and asked to complete a self-report instrument about knowledge of hypertension, beliefs about their prescription medicines, and the Brief Medication Questionnaire. Analysis was done using frequencies and cross tabulations Results: A total of 387 patients were approached. However, only 349 patients consented to partake in the study. Majority (about 80%) of the respondents agreed that their hypertension medication protects them from getting worse. However, about half of the respondents had concerns about long term effects of their medicines. About three-fifths of the respondents believed that doctors place too much trust on medicines and more than two-fifths believed that medicines are addictive. Conclusion: Patients had inadequate knowledge about hypertensive disease and medications which influenced adherence negatively. There was a positive association between the beliefs about the necessity of their medication and adherence but a negative one between the beliefs of concern, harm and overuse and adherence. Intervention strategies of educating and addressing beliefs of patients on hypertensive disease and medications may improve non - adherence and consequently treatment outcomes.
Penerapan Augmented Reality sebagai Penampil Model 3D Rumah Berbasis Android pada The East View Residence
Authors: Ibrahim Renata Roby , Gatc Jullend
Published: November 2021

The East View Residence merupakan sebuah produk rumah yang ada di Kota Bekasi, denganterus berkembang pesatnya pembangunan infrastruktur di Kota Bekasi membuat The East View Residenceharus mampu bersaing dengan kompetitor lainnya. Pemanfaatan teknologi augmented reality dalambidang bisnis bukanlah hal yang baru, khususnya pada bidang pemasaran atau marketing. Penelitianini bertujuan untuk mengembangkan sebuah aplikasi augmented reality berbasis Android yang mampumemanfaatkan brosur sebagai image target dalam menampilkan informasi terkait dengan produkrumah yang ditawarkan oleh The East View Residence dengan pendekatan Iterative Development.Berdasarkan hasil dan evaluasi, penelitian ini berhasil implementasikan metode penelitian IterativeDevelopment dalam mengembangkan sebuah aplikasi yang dimanfaatkan untuk kegiatan marketingyang menarik dan interaktif serta memberikan nilai tambah untuk media brosur itu sendiri.
Aplikasi Portofolio Dosen Untuk Pengelolaan Data Kegiatan Tridharma Perguruan Tinggi
Authors: Ziveria Mira , Rusli Muhammad
Published: November 2021

Tugas utama dosen adalah melaksanakan tridharma perguruan tinggi. Supaya pelaksanaantugas dosen berjalan sesuai dengan peraturan dan undang-undang maka diperlukan evaluasi.Evaluasi dilakukan dalam bentuk penilaian dan pengukuran kinerja dosen dalam periode waktutertentu. Evaluasi kinerja dapat dilihat dari beberapa proses seperti penilaian Jabatan Fungsional danAkademik Dosen, Sertifikasi Dosen, Beban Kerja Dosen, dan lain-lain. Semua evaluasi kinerja dosenmembutuhkan data portofolio yang memuat kegiatan tridharma perguruan tinggi yang dilaksanakanoleh dosen dalam periode waktu tertentu. Penelitian ini bertujuan untuk membangun aplikasi portofoliodosen untuk pengelolaan data kegiatan tridharma perguruan tinggi menggunakan System DevelopmentLife Cycle (SDLC), perancangan sistem menggunakan UML, penyimpanan data pada MySQL danpemrograman dengan PHP. Hasil penelitian adalah sebuah aplikasi portofolio dosen yang diharapkandapat memudahkan dosen maupun perguruan tinggi mengelola data kegiatan tridharma yang telahdilaksanakan oleh dosen pada periode waktu tertentu.
Sistem Informasi Human Resource Pada PT Sinar Raflesia Selatan Berbasis Web
Authors: Indriyani Utami , Ziveria Mira
Published: November 2021

PT Sinar Raflesia Selatan merupakan perusahaan bahan kimia yang masih menggunakan sistem human resource secara konvensional dalam menangani data karyawan, absensi, izin dan cuti, sehingga HRD PT Sinar Raflesia Selatan memerlukan waktu yang cukup banyak dalam menangani masalah yang berhubungan dengan data-data tersebut. Kondisi proses sistem yang sedang berjalan hingga saat ini, jika HRD PT Sinar Raflesia Selatan kurang teliti dan kurang giat dalam menangani yang berhubungan dengan data-data tersebut maka data-data yang dikelola tidak akan cepat selesai dalam jangka waktu yang dimiliki. Penelitian ini bertujuan untuk merancang dan membangun sebuah sistem informasi human resource berbasis web yang meliputi penyajian informasi data karyawan, absensi karyawan, ijin karyawan dan cuti karyawan dengan menggunkan metode pengembangan sistem waterfall yang meliputi analisa sistem dengan menggunakan cross functional diagram dan  fishbone diagram, perancangan sistem  dengan menggunakan pemodelan Unified Modelling Language (UML), pengembangan dan pemrograman sistem menggunakan bahasa pemrograman Hypertext Preprocessor (PHP) dan basis data Structure Query Language (SQL) serta pengujian sistem menggunakan black box testing. Hasil penelitian ini adalah sebuah sistem yang dapat digunakan untuk mengelola data karyawan, absensi, izin dan cuti.
Sistem Penerimaan Siswa Berbasis Web Di SMK Spes Patriae
Authors: Driantama Dhani Fajar , Fryonanda Harfebi
Published: November 2021

Pendidikan merupakan hal yang mungkin dianggap penting oleh banyak orang. Proses penerimaan siswa adalah langkah pertama yang dilakukan untuk mengenyam pendidikan. SMK Spes Patriae merupakan salah satu SMK yang memiki beberapa permasalahan pada proses penerimaan siswanya, seperti kesalahan pencatatan data dan antrian yang terjadi. Kepala sekolah berharap proses penerimaan siswa dapat terkomputerisasi sehingga visi dari sekolah ini untuk perkembangan teknologinya dapat semakin terwujud. Metode pengembangan sistem yang digunakan dalam penelitian ini ialah prototype, dengan tahapan seperti: (1) pengumpulan kebutuhan; (2) perancangan prototype; (3)pembangunan prototype; (4)evaluasi customer; (5) perbaikan prototype; dan (6) pembangunan sistem. Hasil akhir dari penelitian ini ialah sistem penerimaan siswa berbasis web di SMK Spes Patriae, yang dapat meminimalisir kesalahan pencatatan data dan juga menghindari antrian yang terjadi saat proses penerimaan siswa.
Book review - Cultivating the Nile: the everyday politics of water in Egypt
Authors: Agrawal Tanvi , Shah Rinan , Mahajan Rashmi , Vora Anav
Published: November 2021

Book review of “Cultivating the Nile: The Everyday Politics of Water in Egypt” written by Jessica Barnes (2014). The book presents the everyday interactions of the communities and the state with the Nile River.
Oil, protein content and fatty acid compositions of soybean genotypes evaluated in double cropping system at the eastern mediterranean in Turkey
Authors:   Eastern Mediterranean Agricultural Research Institute, Turkey, Cubukcu Pinar , Sahar Korhan ,   Eastern Mediterranean Agricultural Research Institute, Turkey, Oluk C. Aylin ,   Eastern Mediterranean Agricultural Research Institute, Turkey
Published: November 2021

Soybean (Glycine max (L.) Merrill) is very important crop for food, protein, and oil both human and animal feeding. The aim of this study determinate oil ratio, protein ratio and fatty acid compositions of Soybean breeding lines developed from Eastern Mediterranean Agricultural Research Institute (EMARI). This study was conductucted in double cropping system at the Eastern Mediterranean Agricul-tural Research Institute ( EMARI), Turkey in 2019 growing seasons. Through this study, it was realised that the fatty acid composition of soybean lines ranged from 11.34-9.80 for palmitic acid, 4.30-6.54% for stearic acid, 26.16-34.11% for oleic acid, 42.82-48.12% for linoleic, and 4.54-5.43% for linolenic acid in double cropped soybean. Oil content was found 22.4%, protein content was 40.9 % DA 12-14-3 and DA 12-15-39-40 soybean lines repectively.
Viticultura biologică - o necesitate a dezvoltării durabile
Authors:   Institute of Genetics, Physiology and Plant Protection, Republic of Moldova, Alexandrov Eugeniu , Gaina Boris ,   Academy of Sciences of Moldova
Published: November 2021

The primary imperative of the sustainable development of the wine sector is to obtain organic pro-ducts, with low consumption of resources, in conditions of increased economic efficiency and the use of tec-hnological links that contribute to reducing energy consumption and protecting the environment. As a result of crossing Vitis vinifera L. with Muscadinia rotundifolia Michx. interspecific vine genotypes have been obtai-ned and identified that can be multiplied by pruning, without grafting, thus obtaining rhizogenic propagating material that contributes to reducing the costs of setting up vineyards. They were approved as table grape vari-eties: "Malena", "Nistreana" and "Algumax" and grape varieties for fresh consumption and processing: "Au-gustina", "Alexandrina" and "Amethyst". By creating plantations, it will contribute to the extension of the area to the northern limit of vine cultivation and obtaining products derived from the "organic" category.
Parfum perfect soi timpuriu de Salvia sclarea L.
Authors:   Institute of Genetics, Physiology and Plant Protection, Republic of Moldova, Balmus Zinaida , Cotelea Ludmila ,   Institute of Genetics, Physiology and Plant Protection, Republic of Moldova
Published: November 2021

The biological Salvia sclarea L. (sage) is a species with a special economic value, determined by the essential oil that has multiple uses in perfumery, cosmetics, aromatherapy, food, etc. The variety Par-fum Perfect is a triple hybrid with constant heterosis. The content of essential oil was determined three times per season through hydro distillation in Ginsberg apparatus and recalculated for dry matter. The production of essential oil in two years of harvesting constitutes 73,5kg/ha (8,7 kg/ha in first year and 64,8 in second year). The variety's efficiency is 3,2kg essential oil of per ton of inflorescences.
Iarba de fier - specie aromatică în colecția IGFPP
Authors:   Institute of Genetics, Physiology and Plant Protection, Republic of Moldova, Chisnicean Lilia , Gille Elvira ,   Center of Biological Sciences „Stejarul”, Romania
Published: November 2021

Sideritis of the Genus Sideritis - introducers of the spicy aromatic collection. Sideritis is a genus of annual and perennial plants of the family Lamiaceae. The plant has a pleasant aroma and many medic-inal benefits. Foliage and inflorescences are sold as unusual tea in all Mediterranean countries. Reproduc-tion of the plant was carried out by seedlings, which were obtained from seeds, or vegetative using cut-tings from annual shoots. As a result of introduction studies, we managed to propagate and introduce in our collection two of its subspecies - Sideritis scardica and S.taurica, as medicinal and spicy-aromatic, drought-tolerant plants.
Manifestarea productivităţii genotipurilor de in (Linum usitatissimum L.) cultivat în diferite epoci de semănat
Authors:   Institute of Genetics, Physiology and Plant Protection, Republic of Moldova, Cutitaru Doina
Published: November 2021

Flax is a known but extremely rare crop for the Republic of Moldova. The potential level of agri-cultural production is generally considered to be determined by physical factors such as quality of the soil, quality and availability of water and the prevailing climate. Current studies cover at the international level the following directions: increase of productivity potential, increase of resistance to unfavorable bio-tic and abiotic factors, improvement of qualitative yield indices. The seed quality and seed production are known to be conditioned by the optimum planting date and the technological level used.
Reacția unor linii de tomate la izolatele fungului Alternaria alternata
Authors:   Institute of Genetics, Physiology and Plant Protection, Republic of Moldova, Mihnea Nadejda
Published: November 2021

The paper presents the results of the appreciation of some tomato lines based on the resistance to the fungal pathogen Alternaria alternata. Culture filtrates (CF) of pathogen in the most cases did not significantly influence for the seed germination. A more obvious impact was manifested in the case of the root and the stem, the deviations from the control constituting -38.2…. -69.6% for the root and -40.7… -72.6% - for the stem. It was found that the greatest importance in the reaction to A. alternata isolates for seed germination had the genotypic factor, and for root and stem growth - the isolation factor - 95.7-91.0%.
刑事法裁判精選──連續犯一部不能證明犯罪者得聲請再審（109台抗大1221）
Authors: 林鈺雄 林鈺雄 , 王士帆 王士帆
Published: November 2021

最高法院2021年4月公布刑事裁判774則，本期精選16則，其中包括刑事大法庭109年度台抗大字第1221號裁定。
禁止女性夜間工作違憲！──釋字第807號
Authors: 徐婉寧 徐婉寧
Published: November 2021

勞動基準法第49條第1項自民國73年制定以來，即禁止女性勞工夜間工作，然此規定日前經釋字第807號解釋認定違反憲法第7條保障性別平等之意旨，應自釋字第807號解釋公布之日（110年8月20日）起失其效力。本號解釋雖肯認勞動基準法第49條第1項禁止女性夜間工作之立法目的在於追求保護女性勞工之人身安全、免於違反生理時鐘於夜間工作以維護其身體健康，並因此使人口結構穩定及整體社會世代健康安全等，均屬重要公共利益，但僅限制女性有違性別平等且其手段與所欲達成之目的間顯然欠缺實質關聯，故而宣告違憲。
Kulturarvspedagogikk i barnehagen: Om små barns sanselige møter med historie og tradisjon
Authors: Holst Buaas Ellen
Published: November 2021

Hvordan kan vi som pedagoger, ivareta historie og tradisjonsformidling i barnehagen? Min bakgrunn for å reflektere rundt denne problemstillingen er en faglig interesse for et innhold som har fått relativt lite oppmerksomhet innenfor pedagogiske institusjoner, men som jeg mener har stor betydning i arbeid med små barn. Det gjelder formidling av historie og tradisjon via de fysiske omgivelsene, det som er til å ta og føle på. Teksten bygger på kilder innenfor fagene pedagogikk, samfunnsfag, historie og kulturhistorie. Egne erfaringer fra arbeid i barnehage og førskolelærerutdanning vil bli trukket inn. Tematikken kan ses i sammenheng med forvalteransvaret overfor natur og kultur, som framheves i verdigrunnlaget til den norske rammeplanen for barnehagen. For øvrig tas det i artikkelen utgangspunkt i en norsk kontekst.
Fair play i barnehagen: Et viktig bidrag i barns sosial-etiske danning
Authors: Olsen Sæle Ove
Published: November 2021

Artikkelen tematiserer idrettskonseptet fair play som en viktig etisk refleksjons- og handlingskompetanse hos barn, som barnehagen har et ansvar for å fremme og utvikle. Fair play utgjør de etiske normer og verdier som idretten er underlagt, som for eksempel at man viser respekt for sine motspillere og at man følger de spillregler som gjelder. Artikkelen peker på at fair play synes å utgjøre en fellesnevner både for idrett og lek, og at det dermed kan fungere som et ethos, ikke bare for idretten, men også for barns lek. Siden det i fair play implisitt ligger en vekt på etisk vurdering/refleksjon (fair), direkte knyttet til lekens utøvelse (play), vil konseptet kunne representere en avgjørende kvalitet i forhold til barns sosial-etiske danning. Artikkelen drøfter også barns lek og fair play-holdninger i lys av voksenrollen og barnehagens rammeplan.
Föräldraskap, utvecklingstörning och vuxenblivande
Authors: Engwall Kristina
Published: November 2021

I Sverige uppmanas de allra flesta till att bli föräldrar men vissa kategorier såsom exempelvis personer med utvecklingsstörning förväntas avstå från föräldraskap. Dessa motstridiga tendenser påverkar hur frivilligt barnlösa uppfattas. Artikeln bygger på intervjuer med 19 barnfria kvinnor och män i Sverige varav fyra tillskrivs en utvecklingsstörning. Huvudsakligen diskuteras de motiv som endast informanterna med utvecklingsstörning berör för sin barnfrihet såsom föräldraskapets mödor ochrisker att överföra ärftliga sjukdomar. Föräldraskap ses ofta som en markör för vuxenblivande och samhällsdeltagande. I artikeln diskuteras också hur barnfria på andra sätt försöker nå en accepterad vuxenstatus. Barnfria med utvecklingsstörning kämpar hårt för att bli sedda som vuxna överhuvudtaget. I denna kamp är potentiellt föräldraskap ett underkommunicerat tema. Deras liv präglas av att de i de allra flesta sammanhang betraktas som ”utvecklingsstörda”.
Thinking relationally: Disability, families and cultural-historical activity theory
Authors: Ingólfsdóttir Jóna G. , Traustadóttir Rannveig , Egilson Snæfríður Þóra , Goodley Dan
Published: November 2021

It is commonly expressed by parents of disabled children within the Nordic region that there is a mismatch between the official aims of the welfare state and the services provided. In an attempt to explore ways to improve welfare services for disabled children and their families this article proposes three social-relational approaches to disability, family, and service systems which combined may create a basis for new and dynamic ways of working with families. The first approach is a relational understanding of disability, the second a family-centred theory characterized by partnerships with parents, and the third a cultural-historical activity theory emphasizing inter-organizational learning as a method to develop services. Developing ways to fulfil the welfare states’ promise of equality and human rights for all is particularly relevant now when all the Nordic countries are currently striving to meet the demands of the new UN Convention on the Rights of Persons with Disabilities.
On Translation of Puns in Sitcoms Based on Functional Equivalence Theory—Taking Yes, Minister as an Example
Authors:   School of Foreign Languages and Literatures, Lanzhou University, Lanzhou 730000, Gansu, China, Wang Liangcheng
Published: November 2021

In situation comedies, pun is one of the most effective means of creating comic effect and takes up a considerable part. However, if incorrectly or improperly translated, it can be almost impossible for puns to get across its audience, even when the audience is somewhat capable of English. The reason is that pun, in essence, is a figure of speech, which requires certain knowledge of English literature and culture. The translation of English movies and TV series has become fairly sophisticated, but studies on the translation of pun are relatively rare. This article will introduce and study pun both in Chinese and English literature by the approach of contrast, and discuss the translation methods of puns from the perspective of functional equivalence theory; and then it will take the Chinese subtitle of the famous situation comedy series Yes, Minister as examples to analyze and study the translation methods and strategies of puns used in situation comedies.
Analysis on the Construction of Chinese Minority Language and Literature Major Based on the Background of “Double First-class”
Authors:   Northwest Minzu University, Lanzhou 730030, Gansu, China, Gong Min
Published: November 2021

Higher education has achieved unprecedented development in recent years, and the country is paying more and more attention to the development direction of higher education. The construction of “double first-class” is an important strategy for implementing the strategy of strengthening the country with talents. Building a number of key or characteristic colleges and majors into world-class standards will play a huge role in revitalizing the nation and enhancing the overall national strength. The introduction of “double first-class” has allowed many universities and majors to re-examine their future development directions. As a major with local ethnic characteristics, the Chinese Minority Language and Literature major also needs more accurate positioning and planning for its construction. This article will elaborate on the opportunities and challenges faced by the minority language and literature major under the background of “double first-class”, the ideas for professional development and construction, and the significance of developing the major, and analyze the construction of the Chinese minority language and literature major.
Cultivation and Innovation: Chinese Excellent Traditional Culture and Sinicization of Marxism
Authors:   Party School of the Sichuan Provincial Committee of the Communist Party of China, 56 Guanghua Village Street, Chengdu, Sichuan, China, Yu Jingkang
Published: November 2021

China’s excellent traditional culture has its own intrinsic value, in the process of Marxism in China, the Chinese communists will Marxist theory and this value combined, not only makes the value of China’s excellent traditional culture to the extreme, but also to their own development added new elements and vitality; Marxism was introduced into China and became Sinicized Marxism. From the perspective of culture, it mainly benefited from the cultural soil and cultural context provided by the excellent traditional Chinese culture, which enabled the Chinese people to understand and disseminate the content of Marxist theory through various forms and channels. The excellent Chinese traditional culture has made its own contribution to the development of Sinicization of Marxism, which also provides a good opportunity for inheriting and developing the excellent Chinese traditional culture.
Construction of Digital Culture Copyright Protection System Based on Blockchain Technology
Authors:   Nanjing University of Posts and Telecommunications (NJUPT), Jiangsu, China, Zhou Xiaoyun
Published: November 2021

Digital cultural copyright protection is an important means of digital cultural works protection. The existing digital cultural copyright protection has some problems in data storage security, rights confirmation efficiency, traceability means and copyright transaction. As an emerging technology in the Internet era, Blockchain can mobilize the enthusiasm of the whole network nodes and improve the security and reliability of digital culture copyright protection. By analyzing the applicability of Blockchain technology in digital culture copyright protection, a digital culture copyright protection system based on Blockchain technology is constructed.
Globe-salvaging treatment of amelanotic uveal melanoma with posterior extraocular extension
Authors: S Maniar Arpita , Niedt George , T Langevin Spencer , P Marr Brian
Published: November 2021

Introduction: Extraocular extension (EOE) of uveal melanoma is rare and generally associated with poor systemic prognosis.

Case Report: We report a patient with amelanotic uveal melanoma with an extraocular extension managed with combination of surgical resection of the posterior extraocular extension along with transpupillary thermotherapy (TTT) to the choroidal lesion, thereby salvaging the globe. To the best of our knowledge, we are the first case to report such combination treatment for amelanotic uveal melanoma with posterior extension without evidence of orbital recurrence or systemic metastasis over a follow-up period of thirteen years.

Conclusion: Careful resection of the extraocular tumor component along with aggressive treatment of the primary intraocular tumor may achieve globe salvage in carefully selected cases.
A-1 Jurisprudencial Differences Between Sahabah (R.A), Causes and Effects: An Analytical Study
Authors: Ul Hassan Muhammad Asim , Ahmad Hafiz Iftikhar
Published: November 2021

One of the main reasons for the features of Islamic jurisprudence is the differences between different schools of jurisprudence which get Oxygen from the theology of Sahaba and this is certainly a mercy for the ummah. This difference of opinion among the scholars on the rules of jurisprudence is in fact a natural consequence of the ijtihad differences of the Sahabah era. People used to refer directly to Sahib Shariat(ﷺ), usually the answers to the questions would come throughout the would solve the problems through their  Ijtihad which have the status of revelation. Necessity was very rare at that time and in practical life the Companions kept an eye on every single action and deed of the Holy Prophet (ﷺ) because the pattern was his own and each Companion understood and preserved his instructions, fatwas and issues according to his own understanding and signs. The Qur'an would determine the value and status of each action (abahat, istihab, wajub, etc.). But when the Prophet (ﷺ) passed away, unsolved issues were resolved through ijtihad. In this research Paper, this theme has been analyzed briefly by the authentic resources.
U-1 Analytical Study of Imam Shami’s Tafseeri Points in Sublul Huda
Authors: Tahir Muhammad , Ahmad Hafiz Iftikhar
Published: November 2021

Allah sent the Prophets (peace and blessings of Allah be upon them) to lead mankind out of disbelief, polytheism and misguidance, and to call them to Islam and guidance. To carry forward this struggle of humanity, the great scholars and leaders of this Muslim Ummah went ahead. Are there any commentators, narrators and biographers among them? One of these biographers is Imam Muhammad ibn Yusuf al-Shami, (942 AH) was born in Salehiya, a town in Damascus, Syria and died in the town of Barquqiyah in Cairo. The sources of life of the Prophet (peace and blessings of Allah be upon him) are the Holy Qur'aan, books of hadith and books of Shamaa'il, etc. A well-known book on the subject is "Sibal-ul-Huda wal-Rashad fi SiratKhair-ul-Ibad" written by Imam Muhammad ibn Yusuf al-Shami. In the present article, we presented the verses of The Holy Quran which are used in Sublul Huda to know his tafseeri points, causes of ‘Nazool’ and methodology. Imam Shami discussed several verses of The Holy Quran in his book at different places to state life of the Holy Mohammad PBUH. He mentioned many times one verse of the Holy Quran under different topic and chapters, and he attained different meanings and concepts from that verse to describe life of the Holy Prophet Mohammad PBUH. In this article, it is analyzed that how he get meanings from verses.  How Imam shami describes the life of Holy Prophet PBUH in differentways. Furthermore it will be discussed the introduction of Imam Shami, Sublul Huda and its methodology.
Computational Analysis of the Messenger RNA Variants Encoding Two Isoforms of the High-mobility Group box 1 Protein
Authors:   Sofia University “St. Kliment Ohridski”, Karagyozov Luchezar , Todorova Jordana ,   Bulgarian Academy of Sciences
Published: November 2021

High-mobility group box 1 protein (HMGB1) is a multifunctional nonhistone chromosomal protein. This widespread nuclear protein has a dual function-in the nucleus - it binds DNA and participates in practically all DNA-dependent processes. On the other hand, the protein plays an important role in the extracellular matrix as an “alarmin”, which interacts with certain receptors and stimulates biochemical pathways, associated with carcinogenesis and metastasis. HMGB1 is a critical damage-associated molecular pattern molecule, has been implicated in several inflammatory diseases and cancer types. This universality makes it an attractive target for innovative therapeutic strategies in the treatment of various diseases. The updated database for the HMGB1 gene, encoding the high-mobility group box 1 protein, was used for computational analysis of the annotated mRNA splice variants. Results showed that five of the splice variants encode an HMGB1 protein, containing 215 amino acid residues. However, two of the splice variants encode a shorter HMGB1 protein with 158 residues. Presently, the existence of a shorter HMGB1 protein is not registered in the protein databanks. This inconsistency is not yet resolved.
La psicología del arte analizada desde la melancolía en la obra “El laberinto del minotauro”
Authors: Arredondo Gamis Raul Demetrio , Dueñas Silva Slink Victor
Published: November 2021

La melancolía en “El laberinto del minotauro” de Ricardo Córdova Farfán, es una investigación reflexiva y teorética inmerso en el campo de la estética freudiana. Este artículo se fundamentó bajo la premisa de que las estructuras del inconsciente del psiquismo de pintor tenían una relación directa con su obra, puesto que la creación artística no puede disociarse del inconsciente del creador, sino es un reflejo fiel de su percepción, de su mundo interior y de su imaginación. Así, el propósito del artículo fue analizar a nivel del psicoanálisis los presupuestos psicológicos en la obra "El laberinto del minotauro" de Ricardo Córdova Farfán, incidiendo en la teoría de la melancolía. Asimismo, se tuvo como objetivo específico Analizar a nivel de la psicología del arte y la estética algunas obras de Ricardo Córdova donde se observa la presencia del temperamento melancólico. Para la comprensión, el análisis y la interpretación de las obras de Córdova, se utilizó la hermenéutica de los símbolos, por ser el método más adecuado para esta clase de discurso. Se concluyó que “El laberinto del minotauro” de Ricardo Córdova; es una alegoría a la melancolía y a la imposibilidad de encontrar la libertad plena. El pintor recrea el mito griego del minotauro, pero desde una visión del arte moderno. Bajo la luz de la teoría psicoanalítica los personajes que rodean a Asterión, no sólo reflejan ciertos estados de melancolía como producto del desencanto con la realidad, sino reflejan sobre todo algunas estructuras oscuras del inconsciente del ser humano.
Escenarios del Desarrollo Histórico de la Investigación Científica en Nicaragua, período de 1950 al 2021, Génesis y Perspectivas
Authors: Pedroza Pacheco Manuel Enrique
Published: November 2021

El mundo moderno es muy dinámico y complejo, con cambios evolutivos acelerados que conllevan a nuevos retos y desafío cada día. El ser humano está enfrentando cada día problemas emergentes de mayores dimensiones, de origen multicausal y efectos multidimensionales. Por tanto, es muy importante reflexionar sobre el desarrollo histórico de la investigación científica en Nicaragua, para conocer mejor de dónde venimos y hacia dónde vamos, su génesis y perspectivas.
La Teoría Fundamentada como camino cualitativo en el estudio de la vejez: una revisión narrativa
Authors: Reyes Álvarez Sandra , Pastorino María Sol
Published: November 2021

El objetivo de esta revisión narrativa, es conocer la contribución de la Teoría fundamentada como método cualitativo en el estudio de la vejez.

Se realizó búsqueda virtual, en las bases de datos de lengua inglesa Medline y Google académico, iniciando desde el 2007 al 2018, encontrándose 40 artículos originales de 14 países en revistas especializadas que llevaran las palabras claves de teoría fundamentada y vejez. Se realizó búsqueda bibliográfica, sistematización de datos, selección de los artículos, para luego realizar el análisis y evaluación final.

Los resultados indican que la Teoría fundamentada fue utilizada en su mayoría por disciplinas sociales como: Enfermería, Psicología y Sociología, en países como España, Suecia, Canadá, México y Estados Unidos, predominando las mujeres como autora y coautoras. La Teoría fundamentada fue utilizada como único método cualitativo en la mayoría de artículos; aplicando las entrevistas en profundidad cómo única técnica de recogida de datos. Estos resultados denotan el avance de la Teoría fundamentada como metodología de investigación cualitativa, en el estudio de problemas sociales, siendo muy útil para profundizar en temas como la vejez, permitiendo la captura de vivencias, experiencias y emociones, tal y como lo expresan los informantes claves.
Mutaciones genéticas asociadas a cáncer de mama hereditario en mujeres nicaragüenses
Authors: Martínez González Jackeline de Fátima , Muñoz Gaitán Marlene del Rosario , Corriols Molina Marianela , Silva Arrechavala José René
Published: November 2021

Introducción: La etiología del cáncer de mama es multifactorial, sin embargo, se ha evidenciado que la mayoría son esporádicos y del 5 al 10% de origen genético. Los genes conocidos hasta la fecha y asociados con una predisposición hereditaria al cáncer de mama se han clasificado según su función en genes de alta, moderada y baja penetrancia.

Objetivo: Determinar mutaciones genéticas asociadas a cáncer de mama hereditario en mujeres nicaragüenses.

Materiales y método: 39 mujeres con diagnóstico histopatológico de cáncer de mama fueron reclutadas para participar en el estudio, previo consentimiento informado. Se tomó 5ml de sangre periférica de cada una de las pacientes para la extracción del ADN, luego se realizó el test genético a los genes BRCA1, BRCA2, Tp53, PALB2, CDH1, PTEN y CHEK2, determinando su significado clínico comparando las secuencias con las bases de datos del Breast Cancer Information Core (BIC) y ClinVar.

Resultados: El 10.2% (4/39) de las pacientes estudiadas son portadoras de una mutación patogénica en BRCA2 (5%), Tp53 y PALB2 (2.5% respectivamente), asociadas a cáncer de mama de origen hereditario. También se identificaron variaciones de significado clínico benigno, inciertas, variantes que aún no han sido reportadas en las bases de datos y otras con conflicto de patogenicidad.

Conclusión: Es necesario e importante incluir el diagnóstico molecular en pacientes nicaragüenses en riesgo a desarrollar cáncer de mama de origen hereditario, para su propio bienestar y el de sus familiares, logrando un diagnóstico precoz, mejorar la terapia y el seguimiento. Por lo tanto, recomendamos se integre el cribado genético para las mujeres nicaragüenses en riesgo a desarrollar esta enfermedad y en aquellas que ya la padecen.
Sistematización de la experiencia del Educador en la Comunidad Terapéutica Cenicsol en el tratamiento de adultos adictos a Sustancias Psicoactivas
Authors: Zamora Noguera René Alonso , Amador Jiménez Dustin Ezequiel
Published: November 2021

Eje de sistematización: La experiencia en la comunidad terapéutica se sistematizó teniendo como eje la reconstrucción e interpretación crítica del rol del educador en el tratamiento de adultos con trastornos por consumo de sustancias psicoactivas del programa residencial de Cenicsol, mientras que el objetivo general es desarrollar una evaluación crítica del rol del educador en la comunidad terapéutica y el tratamiento.

Método: Se utilizó la metodología para sistematizar experiencias de cinco momentos principales: el punto de partida; las preguntas iniciales; recuperación del proceso vivido; la reflexión de fondo y finalmente los puntos de llegada. Los instrumentos que se aplicaron fueron la entrevista semi-estructurada. Se entrevistó a la directora terapéutica; dos terapeutas; tres educadores y tres usuarios de la comunidad terapéutica de adultos.

Algunos de los resultados más relevantes son: La comunidad terapéutica es un ambiente residencial libre de drogas, es un sistema altamente estructurado que tiene como característica fundamental la existencia de un sistema de presión artificial, la que obedece al propósito fundamental el cual es activar la patología del adicto en tratamiento y promover la rehabilitación social. El educador es un facilitador del proceso de recuperación del usuario, coordina actividades programadas de la comunidad y realiza intervenciones terapéuticas si es necesario. Dentro de las principales estrategias terapéuticas se encuentran la escucha empática y la observación, utiliza técnicas cognitivo conductuales en consejería individual y grupal.
SYNTHESIS AND EVALUATION OF ANTIBACTERIAL, ANTHELMINTIC ACTIVITIES OF SUBSTITUTED BENZIMIDAZOLE DERIVATIVES
Authors: Sharma D , Sharma G. K , Pathak D. , Sharma M. C. ,   Aligarh College of Pharmacy, Aligarh - 202 001, Uttar Pradesh, India.
Published: November 2021

The study was undertaken to synthesize and evaluate antibacterial, anthelmintic activities of N’ (substituted benzylidene)-2-(2-alkyl/aryl-1H-benzo[d] imidazole-1yl) acetohydrazide derivatives. All the novel benzimidazole derivatives were screened for anthelmintic activity against Pherituma posthuma species of earthworms and antibacterial activity against following bacterial strains: S. aureus, B.subtilis (Gram positive) and E. coli and P.aeruginosa (Gram negative). The antibacterial data suggest that compounds having nitro and hydroxyl substitution were more potent and the anthelmintic data suggest that compounds having chloro were most active.
DEVELOPMENT AND VALIDATION OF UV SPECTROPHOTOMETRIC METHOD FOR THE ESTIMATION OF ROTIGOTINE IN NANOSTRUCTURED LIPID CARRIERS
Authors: Prajapati Jagruti B. , Patel Gayatri ,   Department of Pharmaceutics & Pharmaceutical Technology, Ramanbhai Patel College of Pharmacy, Charotar University of Science and Technology, CHARUSAT Campus, Changa, Petlad 388 421, Anand, Gujarat, India
Published: November 2021

Rotigotine (RTG) loaded Nanostructure Lipid Carriers (NLCs) were developed for the treatment of Parkinson’s disease. To estimate RTG entrapped in NLCs, UV spectrophotometric method was developed and validated. The solvent and wavelength of detection were optimized in order to maximize sensitivity of the proposed method. The method was validated for different parameters like linearity, precision, specificity, accuracy, limit of detection (LOD), limit of quantitation (LOQ) and robustness as per ICH guidelines. A wavelength maximum of RTG in methanol: chloroform (6:4V/V) mixture was found at 273 nm. The method was found to be linear in the range of 40 to 200 µg/mL with a correlation coefficient (r2 ) of 0.998. The accuracy of the method was studied by recovery study and % recovery was found in range of 99 to 100.37 %. The LOD and LOQ were found to be 0.09 µg/mL and 6.1 µg/mL, respectively. The method is simple, accurate and requires relatively inexpensive instrument. The method was used successfully for determination of RTG loaded into NLCs.
A GREEN AND FACILE APPROACH FOR ANTIDIABETIC AND ANTI-INFLAMMATORY POTENCY FOR FICUS SUBINCISA FRUIT
Authors: Shukla Abha , Pokhriyal Priyanka , Shukla Rishi K. , Kaur Amanpreet ,   Department of Chemistry, Kanya Gurukul Campus, Gurukul Kangri Vishwavidyalaya, Haridwar- 249 404, Uttrakhand, India
Published: November 2021

Ficus subincisa belongs to the Moraceae family comprising approximately 850 species. Many Ficus species have been used ethnopharmacologically for the treatment of many health-promoting effects. With increasing economical and ecological concerns for several chemical processes, green chemistry is providing various kinds of “green” solvents that can be a recruit for the extraction and isolation of numerous alleviative and important phytoconstituents from plants. The present study was undertaken to prepare crude extracts of F. subincisa fruits with different polarities of green solvents (d-limonene, isopropyl alcohol, ethyl lactate, and hydroalcohol) by using a modified magnetic stirrer extraction method and assessing in vitro anti-diabetic, anti-inflammatory activities by the spectrophotometric method. Among all, ethyl lactate and hydroalcohol fraction of F. subincisa have shown the highest α-amylase and α-glucosidase enzyme inhibitory activity with an IC50 value of 166.91±2.73 and 118.73±0.67 µg/mL, respectively, which were comparable with that of acarbose. At a concentration of 1000 µg/mL, the hydroalcohol and ethyl lactate of fruit produced 134.53±1.23 and 114.67±4.23 µg/mL inhibition of HRBC hemolysis and bovine serum albumin, respectively, as compared with standard drug aspirin and sodium diclofenac. However, there has been no report on the anti-inflammatory and antidiabetic activity of F. subincisa fruit. Therefore this study was aimed to evaluate the anti-inflammatory and antidiabetic activity of F. subincisa fruit extracts of different green solvents. Our study validated the traditional claim with pharmacological data of the Ficus genus. Taken together, these findings imply that the F. subincisa could be useful therapeutic agents to attenuate muscle insulin resistance due to diet-induced obesity and its associated inflammation.
ХАРАТЕРИСТИКА РОСЛИН РОДУ МИКОЛАЙЧИКИ ТА ПЕРСПЕКТИВИ ЇХ ВИКОРИСТАННЯ У МЕДИЦИНІ
Authors: Грицик Андрій , Гнатойко Ксенія
Published: November 2021

Анотанція

Мета роботи. Морфологічний аналіз деяких видів роду Миколайчики. Аналіз сучасної літератури щодо ботанічної характеристики, хімічного складу, розповсюдження та використання в медицині рослин роду  Миколайчики.

Матеріали і методи. В роботі використовували методи патентно-інформаційного  пошуку та  аналізу  даних  сучасної літератури. Проводили морфологічне дослідження видів роду Миколайчики.

Результати та обговорення. Згідно із базою даних  «The Plant list» до роду Миколайчики відносяться 257 визнаних видів, які поширені на території Євразії, Північної та Південної Америки, Африки та Австралії. Зазвичай миколайчики це дикорослі рослини, проте їх успішно культивують в багатьої країнах. До роду Миколайчики відносяться одно-, дво-, та багаторічні трави, висота яких складає від 40 см до 1,5 м в залежності від виду. Стебло пряме, вгорі розгалужене; квіти дрібні, переважно синіх відтінків; плоди покриті лусочками. На території України широко поширеними є миколайчики плоскі, миколайчики польові та миколайчики приморські.

Деякі види миколайчиків вживають в їжу; використовують як декоративну рослину у флористиці. Рослини роду Миколайчики вміщують різноманітні біологічно активні речовини, що проявляють фармакологічну дію на організм людини, тому в народній медицині миколайчики використовують здавна, як спазмолітичний, потогінний, сечогінний, відхаркувальний засіб.

Висновки. Види роду Миколачики це одно-, дво-, та багаторічні трави родини Зонтичні, які поширені по всій земній кулі. Миколайчики  здавна використовують в народній медицині, проте вони не є офіцинальною сировиною, хоча біологічно активні речовини миколайчиків здатні проявляти позитивну фармакологічну дію на організм людини. Насіннєва та сировинна продуктивність миколайчиків є достатньою для промислового культивування. Миколайчики є перспективними лікарськими рослинами та потребують подальшого вивчення для можливості створення нових лікарських засобів.

Ключові слова: миколайчики, eryngium, лікарські рослини, біологічно активні речовини.
The genus Hymenochaete in India (Hymenochaetaceae)
Authors: Mishra Deepa , Sharma J.
Published: November 2021

The paper records 34 species of the genus Hymenochaete Lev. (Hymenochaetaceae) from India out of which 14 species are new records and addition to Indian Mycoflora. All the new records are described and illustrated in detail. The collected material has been deposited in the cryptogamic section herbarium at Botanical Survey of India (NRC) Dehradun (BSD). A key to all the Indian species has been provided for their easy identification.
Zephyranthes candida (Lindl.) Herb. (Amaryllidaceae) – A new record for Odisha, India
Authors: Murugan P. , Kalidass Chinnamadasamy , Panda Pratap
Published: November 2021

Zephyranthes candida (Lindl.) Herb. collected from Mahendragiri hills, Gajapati District, Odisha is reported here as a new distributional record for the state of Odisha. Brief botanical description, nomenclature, ecology and phenolgy of this taxon is provided along with photographs for easily identification.