bluuebunny/crossref_metadata_2025 huggingface dataset:
Major Histocompatibility Complex Allele Persistence in Eurasia and America in the Genus Carduelis (Spinus) During Million Years
Authors: Arnaiz-Villena Antonio , Ruiz-del-Valle Valentín , Muñiz Ester , Palacio-Gruber Jose , Campos Cristina , Gómez-Casado Eduardo , Villa Jose Manuel Martín , Serrano-Vela Ignacio
Published: November 2017

Introduction:

GenusCarduelis(Fringillidaefamily) includes goldfinches, siskins, redpolls, greenfinches and crossbills. Many of the species classified within this genus and other related genera have been grouped by using molecular systematics and the mitochondrial cytochrome b (mt cyt b) gene. According to this, the Eurasian siskin (C. spinus)is the only one extant direct ancestor of several North American finches; North American / South American radiations may have been originated by Eurasian siskin (or extinct relative). In the present work, we aim to perform a study of transpecies and transcontinental analyses of MHC (Major Histocompatibility Complex) Class I alleles in several genusCarduelis/Spinusspecies in order to draw evolutionary conclusions in several wild bird species belonging to the genusCarduelis / Spinus.

Materials and Methods:

Blood was taken from worldwide wild bird species. Passerine phylogeny was done after analysing mtDNA with Maximun Likelihood and Bayesian dendrograms. Major histocompatibility complex alleles were obtained by standard DNA cloning and sequencing.

Results:

We found two matches between MHC-I DNA alleles from different South American siskins at DNA level. Also, it was observed that the Eurasian siskin shares a protein with pine siskin and another with three South American siskins. Eight South American siskins species also share the same MHC protein. In addition, studied songbirds MHC class I intron 2 is longer than that ofGallus gallus.

Conclusion:

We have drawn the following conclusions: 1) We present the first direct evidence that “Minimal Essential MHC” does not exist for birds; one of its main definition characters,i.e.: small intron size does not hold for songbirds. 2) We also report that MHC genes transpecies evolution exist in birds by showing also for the first time that worldwide bird species keep the same MHC protein and DNA alleles. 3) New evidences on MHC alleles conservation from EurasianCarduelis spinus(most ancient) to South American siskins (most recent) during million years support that Eurasian siskin is the parental species for American GenusCarduelis (Spinus)species. It is uncertain whether Eurasian siskin (or extant relative) had initially an Holoartic distribution, including America.
Antidiabetic and Antioxidant Potential of GancidinW from Streptomyces Paradoxus VITALK03
Authors: Ravi Lokesh , Ragunathan Adhithya , Krishnan Kannabiran
Published: November 2017

Background:

The aim of the present study was to analyse the antidiabetic and antioxidant potential of GancidinW (GW) extracted fromStreptomyces paradoxusVITALK03.

Materials and Methods:

Antidiabetic potential of GW was evaluated by assay of α-amylase and α-glucosidase inhibitory activity; haemoglobin glycosylation and yeast glucose uptake. The antioxidant potential of GW was assessed by 2,2-Diphenyl-1-picrylhydrazyl (DPPH) assay, 2,2′-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical cation decolorization assay and superoxide assay. The inhibition of α-amylase and α-glucosidase by GW was also studied byin Silicomolecular docking analysis.

Results:

GW (1mg/ml) showed 69.32% of α-amylase and 54.04% of α-glucosidase inhibitory activity. GW (1mg/ml) prevented haemoglobin glycosylation up to 30.92% and the glucose uptake by yeast cells was increased up to 64.38%. The binding interaction GW with α-amylase showed the least free binding energy of -6.09Kcal/mol and -7.53Kcal/mol with α-glucosidase by docking studies. GW also demonstrated moderate antioxidant activity in all the antioxidant assays performed.

Conclusion:

The results of this study suggests that the antidiabetic and antioxidant potential of GW can be probed further to develop GW as effective antidiabetic agent.
Earthworms Converting Milk Processing Industry Sludge into Biomanure
Authors: Singh Satveer , Bhat Sartaj A. , Singh Jaswinder , Kaur Rajinder , Vig Adarsh P.
Published: November 2017

Aims and Objectives:

The present study was conducted to utilize the Milk Processing Industry Sludge (MPIS) for the purpose of vermicomposting, in two sets of experimentsviz. with earthworms (ME) and without earthworms (MW).

Methods and Materials:

Twenty young non-clitellatedEisenia fetidawere released in each tray. The various parameters like growth, clitellum development, biomass, cocoon production and hatchlings ofE. fetidawere observed after every 15 days, during 90 days of vermicomposting.

Results:

The maximum growth and better responses were observed in ME25mixtures of MPIS which was the minimum ratio of the waste to CD. The physico-chemical analysis (pH, EC, TKN, TOC, C/N ratio, TAP, TK, TNa) and heavy metals (Cr, Cu, Mn, Pb) were also done before and after vermicomposting process. There was a significant increase in TKN (23-46%), and TAP (39-47%), and a decrease in pH (6.2-6.8%), EC (24.6-37.2%), TOC (16.8-37.9%), C/N ratio (23.8-97.9%), TK (26.6-40.6%), and TNa (31.3-53%) and heavy metals (Cr 30.9-40.6%, Cu 32.7-44.6%, Mn 23.9-36.3%, and Pb 32.6-42.9%) from initial to final feed mixtures with earthworms.

Conclusion:

Thus the final vermicompost had excellent physico-chemical properties with all nutrients in plant available forms. The study further strengthens that the vermicomposting is an efficient technique in converting MPIS into nutrient rich biomanure in a short period of timei.e. 90 days.
The Influence of Marine Tourism towards the Quality of Life among Local Tour Operators at Pulau Pangkor, Perak
Authors: Chek Sulaiman Firdaus , Jamaluddin Ely Rouzee , Jaini Norajlin , Hashim Nur Idzhainee
Published: November 2017

Marine tourism is one of the main factors contributing to the growth of the tourism sector in Malaysia. Malaysia is among the countries that have the most beautiful islands with diverse marine life. It is attracting visitors to enjoy the beauty of the sea nature. The vibrant activity is an opportunity for local tour operators to engage in the tourism sector. Therefore, the business activities can provide benefits to the local tour operators, but these also have negative impacts on economic, socio-cultural and environment. A preliminary study was conducted to determine tour operator’s perceptions about the impact of tourism activities related in entrepreneurial of community in Pulau Pangkor. The study involved 150 respondents who joined the local tour operators in the tourism sector. This study used questionnaire survey as the method of data collection. The findings show the marine tourism involving entrepreneurial activity has a high impact on the socio-economic development of the local population and moderate impact to the environment.
Promoting Ageing-in-Place: Design of residential buildings for older people in China
Authors: Gadakari Tulika Suchit , Wang Jingjing , Hadjri Karim , Huang Junjie
Published: November 2017

Ageing-in-place is the most common ageing model in China. Therefore, design of age-friendly residential buildings and neighbourhoods becomes an important factor leading to improvement in older people’s health and quality of life. This paper presents the current situation of the ageing population in Chinese cities by qualitatively analysing existing literature, design standards and conducting stakeholder interviews to understand older people’s housing choices as well as establish physical design factors, challenges and potentials of residential design for older people. The findings will fill the knowledge gap of age-friendly residential models in China and guide better design to meet older people’s needs.
The Physical Factors Affecting to Student’s Life in Higher-Education: A Case Study on Wheelchair-Bounded Students in a Private University
Authors: Tipian Sridara , Sawadsri Antika
Published: November 2017

There are 48.37% in Thailand, who use wheelchairs, but they can be learned. The percentage of the disabled who are in higher education system only 1.61%. The result of physical factors where are not ready. This research focused study of physical factors affecting to wheelchair-bounded student by qualitative research; survey, access audit and the semi-structured interview. Found that factors affecting are entrance, classroom, activities area and restroom. Enhancing technical knowledge to the building manager to responding to all usage. Contributors often avoid seeking help because don't want to feel like a burdensome. The most important is that family are another motive to study.
CHARACTERIZATION OF EXTRACELLULAR PROTEASE FROM VIBRIO METSCHNIKOVII STRAIN XMB 057
Authors: S. Girase M. , B. Gaikwad V. , N. Patil S.
Published: November 2017

From various natural sources on skim milk agar plates 51protease producer bacteria wereisolated by primary screening. Secondary screening was done by zone of clearanceformed by cell free broth on gelatin agar plates. From diameter of zone of clearance potent protease best protease producers Vibrio metschnikovii strain Xmb 057 was isolated. It was biochemically characterized by performing some common biochemical tests. Effect of temperature and pH on protease by Vibrio metschnikovii strain Xmb 057 was studied. Optimum temperature and pH was 500C and 9 respectively make it suitable to be used in leather and detergent industry. Protease was tolerant to Ca++ and Mg++ which suggest its activity in detergents used even in hard water.
Recommendations for Assessment of the Reliability, Sensitivity, and Validity of Data Provided by Wearable Sensors Designed for Monitoring Physical Activity (Preprint)
Authors: Düking Peter , Fuss Franz Konstantin , Holmberg Hans-Christer , Sperlich Billy
Published: November 2017

UNSTRUCTURED

Although it is becoming increasingly popular to monitor parameters related to training, recovery, and health with wearable sensor technology (wearables), scientific evaluation of the reliability, sensitivity, and validity of such data is limited and, where available, has involved a wide variety of approaches. To improve the trustworthiness of data collected by wearables and facilitate comparisons, we have outlined recommendations for standardized evaluation. We discuss the wearable devices themselves, as well as experimental and statistical considerations. Adherence to these recommendations should be beneficial not only for the individual, but also for regulatory organizations and insurance companies.
La Navidad: memorias de un naufragio de Veloz Maggiolo
Authors: Rosario Fari
Published: November 2017

No precisa de resumen.
Rol del agente educativo en activación de rutas de atención de violencias sexuales en la infancia
Authors: Restrepo Segura Yusty Carolina , García Peña John Jairo
Published: November 2017

Este articulo es producto de una investigación, cuyo objetivo fue analizar las experiencias personales y profesionales de agentes educativos de primera infancia, en la activación de rutas de violencias sexuales para el restablecimiento de derechos; se concibió desde un enfoque cualitativo, histórico-hermenéutico, con metodología de Estudio de Caso, del programa público Buen Comienzo de Medellín, Colombia, entre 2016 y 2017, para la información generada, se realizaron entrevistas a 10 de sus agentes educativas. Los resultados principales, mostraron inconsistencia en los procesos de formación y cualificación de las agentes educativas, al activar rutas de atención, ante casos identificados de violencias sexuales, en sus espacios pedagógicos. Como conclusión relevante, se evidenció que –ante eventos de vulneración de derechos–, se actúa más por intuición, que por conocimiento profesional, por lo que, los procesos de restablecimiento de derechos se ven obstaculizados, debido a las inconsistencias en la información, al momento de acceder a una ruta de reparación integral.
Should MTHFR 1298 A>C be tested together with MTHFR 677 C>T polymorphism in women with reproductive challenges?
Authors: Djurovic Jelena , Stojkovic Oliver , Todorovic Jelena , Savic Kristina , Stamenkovic Gorana
Published: November 2017

Methylenetetrahydrofolate reductase (MTHFR) plays a critical role in the
folate metabolism. The polymorphism 677C>T of the MTHFR gene, producing
thermolabile enzyme with decreased function, is widely studied and associated
with many conditions. Additionally, it has been shown that another
polymorphism, 1298A>C, also reduces the activity of this enzyme, although to
a lesser extent. The aim of this study is to evaluate the clinical
informativeness of testing both MTHFR polymorphisms. Genomic DNA, were
extracted from peripheral blood of 180 female patients with pregnancy
complications and 183 healthy female controls, and genotyped for MTHFR 677C>T
and 1298A>C loci, using TaqMan assays. Our study found similar frequency of
alleles and genotypes between two groups. Based on MTHFR 677C>T genotype,
11.7% of patients homozygous for this mutation were under the possible risk.
When the position 1298 was included in the testing, 22.8% of the patients
were heterozygous for both polymorphisms. Additionally, 8.9% of the patients
were homozygous only for the MTHFR 1298 mutation. Although,s there was no
differences compared to healthy control (p>0.05), 43% of patients were found
to have elevated risk which is about four time highers than results with only
MTHFR 677C>T genotyping. After obtaining information for the 677 position,
testing for the second polymorphism (1298A>C) should be considered, since we
have shown that it dramatically increases the rate of detection of patients
who are potentially at risk for MTHFR associated conditions.
Genetic evaluation of growth traits in Iranian Kordi Sheep using random regression model with homogeneous and heterogeneous residual variances
Authors: Mohammadi Ali , Farhadian Mohammad
Published: November 2017

The purpose of this study was estimation of genetic parameter using random
regression model (RRM) with various error variance in Iranian Kordi sheep.
The data (consisting of 7875 weight records from birth to 360 days of age)
were collected during the period 2000 to 2013 from the rearing and breeding
station of Kordi sheep in Shirvan, Iran. The independent variables were
Legendre polynomials (LP) of age at weighing and orders of fit from 2 to 5
were considered. Analyses were carried out fitting sets of random regression
coefficients due to direct additive genetic, direct and maternal permanent
environmental effects, with heterogeneous and homogeneous error variances.
To compare the model were used different criteria such as LogL, AIC, BIC and
LRT. The best fitting RRM among homogeneous error variance was the model
with a LP of fourth order for fixed effect, fourth order for direct additive
genetic and fifth order for direct and maternal permanent environmental
effects (model 4455). Among the models with heterogeneous error variances
different, model 7 (Heterogeneous error variances of 72 various classes),
was selected as the best model. The variances increased along the trajectory
from 3.75 to 12.81, 4.43 to 30.28 and 1.49 to 8.49; 0.25 to 27.94, 0.03 to
12.32 and 0.15 to 22.66 for direct additive genetic, direct and maternal
permanent environmental effect by homogeneous and heterogeneous error
variances, respectively. The direct heritability ranged from 0.15 to 0.41
and 0.11 to 0.56 by homogeneous and heterogeneous error variances,
respectively. Genetic correlation between adjacent test days was more than
between distant test days. This research has demonstrated the possibility of
application of RRM with heterogeneous error variance for genetic evaluation
of Iranian Kordi Sheep.
Transfer of human proinsulin gene into Cucumber (Cucumis sativus L.) via agrobacterium method
Authors: Abookazemi Kameh , Jalali Javaran , Mohebodini Mehdi , Vaseghi Akbar
Published: November 2017

Nowadays, approximately 5.8% in adult population around the world are
suffering by diabetes. It can be caused by an increase in risk factors such
as being overweight. Also it has been estimated that the number of patients
will be doubled in near future and the demands for insulin hormone will be
growing up by 3 to 4 % annually. Therefore, it?s necessary to develop new
methods for hormone production with high rate of capacity in future. By
advanced technology of transgenic DNA, the transgenic plants are introduced
as an attractive system for expression and production of many kinds of
pharmaceutical proteins. In this study, we investigated transfer of Human
Proinsulin Gene into the Cucumber (Cucumissativus L.). Transgenic cucumber
could be a great prospect for future source of eatable insulin
pharmaceutical drugs to be taken by patients.Agrobacterium tumefaciensstrain
LBA4404 carrying proinsulin genes with CaMV 35S promoter was used for the
transformation purpose. The transgenic plants were analyzed by PCR, RT-PCR,
SDS-PAGE, Dot blot and Electrochemiluminescence techniques. Production of
proinsulin in cucumber could be a great prospect in molecular farming of
human proinsulin.
Value priorities of future preschool and class teachers in Serbia in terms of the Schwartz refined value theory
Authors: Marusic-Jablanovic Milica
Published: November 2017

To understand an individual?s behavior, attitudes, and decisions, it is necessary to learn his/her value priorities. In order to explore the structure and hierarchy of values of future preschool and class teachers we conducted a survey (N = 232). It relies on the famous Schwartz value theory in its refined version, applying his PVQ-57 (Portrait Value Questionnaire). The analysis encompassed reliability analysis, goodness of fit, multidimensional scaling, mean rating and ranking, and t-test. The obtained data fits the theoretical model well, and the location of empirical value types can be predicted by the proposed circumplex, except for universalism and benevolence values, which are located in reverse. Several values adjacent in the model appear combined in the data. The value hierarchy starts with Benevolence (Care and Dependability), Self-direction?Action, Security?Personal, Universalism?Concern, and finishes with Humility, Power?Resources and Dominance.
Psychometric evaluation and validation of the Serbian version of “Reading the mind in the eyes” test
Authors: Djordjevic Jelena , Zivanovic Marko , Pavlovic Aleksandra , Mihajlovic Goran , Stasevic-Karlicic Ivana , Pavlovic Dragan
Published: November 2017

?Reading the Mind in the Eyes? test (RMET) is one of the most popular and widely used measures of individual differences in Theory of Mind (ToM) capabilities. Despite demonstrating good validity in differentiating various clinical groups exhibiting ToM deficits from unimpaired controls, previous studies raised the question of the RMET?s homogeneity, latent structure, and reliability. The aim of this study is to provide evidence on psychometric properties, latent structure, and validity of the newly adapted Serbian version of the RMET. In total, 260 participants (61.9% females) took part in the study. The sample consisted of both unimpaired controls (76.5%), and a clinical group of participants that are believed to demonstrate ToM deficits (23.5%), namely, persons diagnosed with schizophrenia and bipolar disorder (54.1% females). RMET has demonstrated fair psychometric properties (KMO = .723; ? = .747; H1 = .076; H5 = .465), successfully differentiating between clinical group and control [F (1,254) = 26.175, p <.001, ?2 p = .093], while typical gender differences in performance were found only in control group. Tests of several models based on the previous literature revealed that the affect-specific factors underlying performance on RMET demonstrate poor fit. The best fitting model obtained included reduced scale with a single-factor underlying the test?s performance (TLI = .953, CFI = .958, RMSEA = .020). Based on the fit parameters we propose 18-item short-form of the Serbian version of RMET (KMO = .797; ? = .728; H1 = .129; H5 = .677) for economic, reliable and valid measurement of ToM abilities.
Anatomic study of septocutaneous system of the human fetuses’ lower leg: Posterior tibial artery
Authors: Stevanovic Goran , Dakovic-Bjelakovic Marija , Djordjevic Boban , Paravina Jadranka , Golubovic Ivan , Jankovic Irena , Radojkovic Milan , Nestorovic Milica , Ignjatovic Nebojsa , Krstic Miljan
Published: November 2017

Background/Aim. Lower-leg septocutaneous system of perforating blood vessels represents the vascular basis of fasciocutaneous flaps. Additionally, it is of a particular importance when designing distally based fasciocutaneous flaps which represent the ?workhorse? in the reconstruction of the distal third of the lower leg and foot. The aim of this study was to analyse the vascular anatomy of posterior tibial artery and its septocutaneous (fasciocutaneous) perforating arterial vessels. Methods. The dissection was conducted on 20 fetuses of both sexes and of gestational age from 20 to 28 weeks. Cluster analysis was applied to the data on vascular anatomy of posterior tibial artery and its septocutaneous performating arterial vessels. Results. A total of 212 perforating arterial vessels was identified. The average number of perforating arterial vessels was 5.32 (ranging from 4 to 7). It was identified that septocutaneous perforating blood vessels are more likely to be found at certain levels (?safe levels of finding perforators?). These are: second, third, fifth and sixth tenth (measured as a distance from intermalleolar line to popliteal crease). Conclusion. The presence of septocutaneous system of perforating blood vessels and reliability of their localization even in the fetal period allows application of these findings in the lower leg reconstructions in children of early age. It also contributes to the greater level of understanding of anatomy of the lower-leg vascular system. Finally, it provides a basis for understanding the development of this system as it is now possible to compare results obtained on fetuses with those obtained on adults.
The impact of the early tenotomy of Achilles tendon on the length and results of congenital clubfoot severe forms treatment
Authors: Rakonjac Zoran
Published: November 2017

Background/Aim. In this paper we present our modification of the Ponseti method which we have been using for the treatment of severe forms of congenital clubfoot since 2007. The aim of this paper was to determine, on the basis of the analysis of results, the impact of the early tenotomy of the Achilles tendon on the length and results of treatment of severe forms of congenital clubfoot. Methods. The study was prospective and lasted from 2007 to 2016 year. It was implemented in the Clinic for Children's Surgery Banjaluka. The Group 1 consisted of the subjects treated by the modified Ponseti method in the period of 9 years (2007?2016). There were a total of 30 subjects (52 feet). There were 20 (67%) of male and 10 (33%) of female subjects. There were 22 (77%) subjects with bilateral and 8 (27%) with unilateral deformity. The Group 2 consisted of the subjects treated by the classic Ponseti method in the period of 9 years (2007?2016). There were a total of 32 subjects (52 feet). There were 26 (81%) of male and 6 (19%) of female subjects. There were 20 (63%) of subjects with bilateral and 12 (37%) with unilateral deformity. We used the Pirani score for: classification of deformity according to the severity, monitoring of results of the correction, determination of indication for tenotomy of the Achilles tendon and for the analysis of results of the treatment. Results. The total length of treatment in the Group 1 was from 6 to 9 weeks (mean = 6.71 ? 0.871), and in the Group 2 from 9 to 12 weeks (mean = 9.92 ? 0.882) (r = 0.86; p = 0.001). There was no difference in the results of the treatment (?2 = 2.372 df = 2 n = 52 p = 0.936. Conclusion. Applying early tenotomy of Achilles tendon in the treatment of severe forms of congenital club foot significantly shortens the duration of treatment and has no negative impact on the results of treatment.
Genetic testing for Best vitelliform macular dystrophy
Authors: Abeshi Andi , Bruson Alice , Beccari Tommaso , Dundar Munis , Viola Francesco , Colombo Leonardo , Bertelli Matteo
Published: November 2017

We studied the scientific literature and disease guidelines in order to summarize the clinical utility of the genetic test for Best vitelliform macular dystrophy (BVMD). BVMD is mostly inherited in an autosomal dominant manner (autosomal recessive transmission is rare). The overall prevalence is currently unknown. BVMD is caused by mutations in the BEST1 gene. Clinical diagnosis is based on clinical findings, ophthalmological examination, optical coherence tomography, electrooculography and electroretinography. The genetic test is useful for confirming diagnosis, and for differential diagnosis, couple risk assessment and access to clinical trials.
Genetic testing for ocular coloboma
Authors: Abeshi Andi , Marinelli Carla , Beccari Tommaso , Dundar Munis , Colombo Leonardo , Bertelli Matteo
Published: November 2017

We studied the scientific literature and disease guidelines in order to summarize the clinical utility of genetic testing for ocular coloboma (COI). COI is inherited in an autosomal dominant manner associated with variations in the PAX6, ABCB6 and FZD5 genes and in an autosomal recessive manner associated with variations in the SALL2 gene. Overall prevalence is 1 per 100,000 live births. Clinical diagnosis is based on clinical findings, ophthalmogical examination, family history, fundus examination and electroretinography. The genetic test is useful for confirming diagnosis, and for differential diagnosis, couple risk assessment and access to clinical trials.
Genetic testing for enhanced S-cone syndrome
Authors: Abeshi Andi , Marinelli Carla , Beccari Tommaso , Dundar Munis , D’Esposito Fabiana , Bertelli Matteo
Published: November 2017

We studied the scientific literature and disease guidelines in order to summarize the clinical utility of genetic testing for enhanced S-cone syndrome (ESCS). The disease has autosomal recessive inheritance, a prevalence of less than one per million, and is caused by mutations in the NR2E3 gene. Clinical diagnosis is based on clinical findings, ophthalmological examination, electroretinography, color vision testing and optical coherence tomography. The genetic test is useful for confirming diagnosis, and for differential diagnosis, couple risk assessment and access to clinical trials.
Genetic testing for inherited eye misalignment
Authors: Abeshi Andi , Fanelli Francesca , Beccari Tommaso , Dundar Munis , Colombo Leonardo , Bertelli Matteo
Published: November 2017

We studied the scientific literature and disease guidelines in order to summarize the clinical utility of genetic testing for Inherited eye misalignment (IEM). Forms of IEM associated with variations in the SALL4, CHN1, TUBB3 and KIF21A genes have autosomal dominant inheritance, whereas those associated with variations in the ROBO3, PHOX2A, HOXA1 and HOXB1 genes have autosomal recessive inheritance. The prevalence of MS is currently unknown. Diagnosis is based on clinical findings, family history, visual acuity testing and fundus examination. The genetic test is useful for confirming diagnosis, and for differential diagnosis, couple risk assessment and access to clinical trials.
Genetic testing for Mendelian cataract
Authors: Abeshi Andi , Zulian Alessandra , Beccari Tommaso , Dundar Munis , Ziccardi Lucia , Bertelli Matteo
Published: November 2017

We studied the scientific literature and disease guidelines in order to summarize the clinical utility of the genetic test for Mendelian cataract (MC). MC is caused by variations in the AGK, BFSP1, BFSP2, CHMP4B, CRYAA, CRYAB, CRYBA1, CRYBA2, CRYBA4, CRYBB1, CRYBB2, CRYBB3, CRYGC, CRYGD, CRYGS, EPHA2, EYA1, FYCO1, FOXE3, FTL, GALK1, GCNT2, GJA3, GJA8, HSF4, LEMD2, LIM2, LSS, MAF, MIP, NHS, PITX3, PAX6, SIPA1L3, SLC16A12, TDRD7, UNC45B, VIM, VSX, and WFS1 genes. The overall prevalence of congenital forms is 71 per 100 000, whereas there is insufficient data to determine the prevalence of the juvenile and age-related forms. Clinical diagnosis is based on clinical findings, age of onset, family history, ophthalmological examination and slit-lamp examination. The genetic test is useful for confirming diagnosis, and for differential diagnosis, couple risk assessment and access to clinical trials.
Genetic testing for Mendelian glaucoma
Authors: Abeshi Andi , Fanelli Francesca , Beccari Tommaso , Dundar Munis , Ziccardi Lucia , Bertelli Matteo
Published: November 2017

We studied the scientific literature and disease guidelines in order to summarize the clinical utility of genetic testing for Mendelian glaucomas, a large heterogeneous group of inherited disorders, classified according to age of onset as congenital glaucoma, juvenile glaucoma and age-related glaucoma. Variations in the TEK, MYOC, ASB10, NTF4, OPA1, WDR36 and OPTN genes are inherited in an autosomal dominant manner and variations in the CYP1B1 and LTBP2 genes have autosomal recessive inheritance. The prevalence of congenital glaucoma is estimated at 1-9 per 100 000, that of juvenile glaucoma at 1 per 50 000, while there is insufficient data to establish the prevalence of age-related glaucoma. Clinical diagnosis is based on clinical findings, age of onset, family history, ophthalmological examination, intraocular pressure, gonioscopy and fundoscopy. The genetic test is useful for confirming diagnosis, and for differential diagnosis, couple risk assessment and access to clinical trials.
Genetic testing for Stargardt macular dystrophy
Authors: Abeshi Andi , Zulian Alessandra , Beccari Tommaso , Dundar Munis , D’Esposito Fabiana , Bertelli Matteo
Published: November 2017

We studied the scientific literature and disease guidelines in order to summarize the clinical utility of genetic testing for Stargardt macular dystrophy (STGD). STGD is mostly inherited in an autosomal recessive manner and rarely in an autosomal dominant manner, with an overall prevalence of 1-5 per 10 000 live births. It is caused by variations in the ABCA4, CNGB3, ELOVL4, PRPH2 and PROM1 genes. Clinical diagnosis is based on ophthalmological examination, fluorescein angiography, electroretinography, visual field testing, optical coherence tomography and color testing. The genetic test is useful for confirming diagnosis, and for differential diagnosis, couple risk assessment and access to clinical trials.
Aportes preliminares a la cuestión cautelar Preliminary contributions to the precautionary issue
Authors: Macchione Nicolás
Published: November 2017

Desde hace un tiempo atrás, con el advenimiento y reinstauración de la democracia en nuestra región se multiplicaron los estudios sobre las medidas cautelares. esta investigación busca ser un aporte preliminar a los crecientes estudios sociológicos jurídicos de las mismas.

En este trabajo se presentan prematuramente algunos números y estadísticas del campo jurídico que creemos necesario tener en cuenta a la hora de ahondar en el estudio de la cuestión cautelar.
Las palabras de la ley y la interpretación normativa. El clásico problema del Derecho y el lenguaje
Authors: Lell Helga María
Published: November 2017

Si bien el reemplazo del Código Civil ha aparejado diversos cambios, una cuestión en común en ambos es la remisión a las palabras de la ley en materia de interpretación. Con este punto de partida, este trabajo pretende realizar una breve enunciación de múltiples jusfilósofos que se han abocado a alguna arista de la relación entre Derecho y lenguaje como forma de dar cuenta de que la misma determinación de qué implica el vínculo antedicho es una tarea dificultosa e interminable. En segundo término, se exponen algunos inconvenientes lingüísticos que surgen de la utilización del lenguaje por parte del Derecho.

Este artículo constituye un avance de investigación y parte de una metodología cualitativa, descriptiva y con énfasis en las discusiones teóricas. Si bien no se presentan resultados, se pretende sintetizar en estas páginas la enorme complejidad de los problemas de la relación lenguaje-Derecho-interpretación.
Aplicación del Art. 1911 del Código Civil y Comercial Unificado sobre los procesos de Usucapión Larga en trámite.
Authors: Ramírez Castañeda Francisco Ramón
Published: November 2017

El Nuevo Código Civil y Comercial Unificado Argentino establece, en el Art. 1911, una presunción legal iuris tantum respecto de la calidad posesoria de las relaciones de poder. Esta presunción, representa una herramienta útil para superar dificultades de producción y valoración de la prueba de la posesión, así como también, deja atrás debates interpretativos del régimen anterior y ayuda a lograr los objetivos de la Usucapión como modo excepcional de adquirir un derecho real por el transcurso del tiempo. Sin embargo, por su naturaleza, contenido, calidad interpretativa y efectos, existe alguna inquietud sobre la posibilidad de aplicarla de manera inmediata a los procesos en trámite y siendo así, será ello el objetivo de estas líneas, es decir, dilucidar si es posible o no su aplicación inmediata y en su caso, que consecuencias acarrea.
Recensión del libro: Las audiencias públicas de la Corte Suprema: Aperturas y límites de la participación ciudadana en la Justicia.
Authors: R. Galván Ezequiel R.
Published: November 2017

Las audiencias públicas de la Corte Suprema:  Aperturas y límites de la participación ciudadana en la Justicia.
“Hacer robusta una posibilidad imaginativa”: Literatura, humanidades y vida pública. (Recensión)
Authors: Sáenz M. Jimena
Published: November 2017

“Hacer robusta una posibilidad imaginativa”: Literatura, humanidades y vida pública. (Recensión)
Recensión del libro: Violencia contra las mujeres. Realidades, desafíos y actores en la implementación de la Ley Nacional 26485 en La Pampa.
Authors: Scarponetti Patricia E.
Published: November 2017

Recensión del libro:

Violencia contra las mujeres. Realidades, desafíos y actores en la implementación de la Ley Nacional 26485 en La Pampa.
El jardín de senderos que se bifurcan: las políticas de seguridad regional de Argentina y Brasil en la década de 1990
Authors: Frenkel Alejandro
Published: November 2017

Este trabajo tiene por objetivo analizar, desde una perspectiva comparada, las motivaciones y posturas que adoptaron Argentina y Brasil en el proceso de reformulación de la seguridad regional durante la década 1990. En particular, el artículo propone que las políticas exteriores en el debate sobre el sistema interamericano de defensa se pueden enmarcar alrededor de tres posiciones multilaterales: de apoyo, de resistencia y revisionista. A partir de ello, se pretende demostrar que Argentina mantuvo una posición mayoritariamente de apoyo, mientras que Brasil oscilaría entre posturas de resistencia –especialmente cuando se ponía en agenda la creación de nuevas instancias o la expansión de funciones en las existentes- y posturas revisionistas.
The World Bank as a political, intellectual, and financial actor (1944-1994)
Authors: Mendes Pereira João Márcio
Published: November 2017

El artículo analiza la historia del Banco Mundial durante sus primeros cincuentaaños. Se argumenta que, desde el principio, el Banco utiliza el crédito como palancapara ampliar su influencia e institucionalizar ideas económicas, visiones del mundo yprescripciones de política en sus clientes. Detrás de su aspecto técnico, el Banco siempreha funcionado, aunque de diferentes formas, en la intersección de los campos político,económico e intelectual a escala internacional, en función de su condición singular deprestamista, actor político y promotor de ideas y recetas acerca de lo que se debe haceren cuestiones de desarrollo capitalista, en clave anglosajona. Basado en una amplia ydiversa literatura y fuentes de la institución internacional, el texto aborda la cuestiónteniendo en cuenta la política de Estados Unidos hacia la institución, los cambios en laeconomía política y la gestión de decisiones internacionales claves de la entidad.
La EPI y las Relaciones Internacionales, ¿Dónde está el Derecho?
Authors: Peixoto Batista Juliana
Published: November 2017

Este trabajo apunta al debate teórico acerca de dos disciplinas fuertemente marcadas por la tradición anglosajona: las Relaciones Internacionales (RRII) y la Economía Política Internacional (EPI), sumando una disciplina que tiene tradición insoslayable en América Latina: el Derecho Internacional. Se construye como réplica a un trabajo sobre la EPI previamente publicado en esta revista (Tussie, 2015), donde se detallan las diferentes vertientes de la EPI, influencias, enfoques latinoamericanos, el contacto con otras disciplinas. Así, a lo largo de este artículo se identifican varios puntos de intersección y coincidencia entre las tres disciplinas, resaltando las visiones compartidas por las visiones críticas del Derecho y la EPI, donde se encuentran amplios espacios de colaboración conceptual, metodológica, desde la región latinoamericana en especial.
KRITERIA VITALITAS BAHASA TALONDO
Authors: Aritonang Buha
Published: November 2017

This research was conducted in the village of Talondo Kondo, District Bonehau, Mamuju, West Sulawesi province with the aim to determine the  vitality of the Talondo languages criteria.The methods of the research was done by doing the field research and the literature study.A fieldwork was conducted to obtain primary data while the library research obtaining secondary data. The sources of data in this study were 81 respondents from Talondo language native speakers. The datas are obtained from observations and questionnaires.To determine the vitality of Talondo language criteria the research used Likert scale models to test and compare the mean index of vitality. The calculation result of subindex groups with respondent characteristics (based on gender, age group, education level, and occupation) showed that the vitality of a Talondo language was setbacks. Because the average value addition and division of the total index of the four variables with the variables gender, age group, education level, and type of work is 0.58. The range value of its included in the index line 3—4 based on visualization in a spider diagram. ABSTRAK Penelitian ini dilaksanakan di Desa Talondo Kondo, Kecamatan Bonehau, Kabupaten Mamuju, Provinsi Sulawesi Barat dengan tujuan untuk menentukan kriteria vitalitas bahasa Talondo. Metode pengumpulan data dilakukan dengan penelitian lapangan dan pustidaka. Penelitian lapangan dilakukan untuk memperoleh data primer, sedangkan penelitian pustidaka untuk memperoleh data sekunder. Sumber data dalam penelitian ini adalah 81 responden penutur bahasa Talondo. Data diperoleh dari hasil pengamatan dan kuesioner. Untuk menentukan kriteria vitalitas bahasa Talondo digunakan model skala Likert dan indeks dengan uji compare mean. Hasil perhitungan kelompok subindeks dengan karakteristik responden (jenis kelamin, kelompok usia, jenjang pendidikan, dan jenis pekerjaan) menunjukkan bahwa vitalitas bahasa Talondo masuk kriteria mengalami kemunduran. Hal itu disebabkan karena nilai penjumlahan dan pembagian rerata indeks total keempat variabel dengan variabel jenis kelamin, kelompok usia, jenjang pendidikan, dan jenis pekerjaan adalah 0,58. Nilai 0,58 termasuk pada garis indeks 3—4 berdasarkan visualisasinya pada diagram laba-laba.
Importance of cytology in the identification of villoglandular adenocarcinoma
Authors: Correia Ana , Vilar Madalena , Teixeira Cidália
Published: November 2017

Endocervical villoglandular adenocarcinoma is a rare subtype of cervical adenocarcinoma. It arises mainly in young and reproductive age women and it has a lower incidence and better prognosis compared to cervical adenocarcinoma. The present case study refers to a conventional cytology performed on a 48-year-old woman within a screening program carried out at a health center of the Local Health Unit of Matosinhos. The objective of this study is to verify the importance of the cytological sample collection method for a better observation and interpretation of the cytological findings in rare neoplastic entities, as well as to reinforce the importance of the application of complementary tests for the elaboration of a conclusive diagnosis. The cytological result of the present case report was atypical glandular cells (AGC) of the endocervical type. Subsequently, a biopsy of the uterine cervix, a conization and a curettage of endocervix were performed, whose histological diagnosis was well differentiated villoglandular adenocarcinoma from the endocervix.
Educación social en la Organización Minuto de Dios. Tras las huellas de un sueño
Authors: Briceño Castañeda Sergio
Published: November 2017

El Minuto de Dios se ha declarado como una obra de carácter social y educativa que ha procurado el desarrollo integral de las comunidades, creada por el padre Rafael García Herreros. Con base en lo anterior y en la búsqueda de nuevos elementos que den cuenta de la propuesta educativa de la obra Minuto de Dios, el proyecto de investigación que se describe de manera general en este artículo pretende revisar la concepción que existe sobre la educación social. La pregunta: ¿Cuál es la concepción que se tiene sobre la educación social en los pregrados de la Facultad de Educación, en las Facultades de la sede principal de Uniminuto y en las instituciones de educación básica y media de la organización Minuto de Dios? es el eje orientador de la investigación. El diseño metodológico se basa en la investigación documental y pretende reconocer la manera como se concibe la educación social en el contexto de la Organización Minuto de Dios.
Una breve reflexión de una experiencia pedagógica
Authors: Bernal Prieto Leonardo Alfonso
Published: November 2017

La reflexión sobre las prácticas sociales es una necesidad a la hora de pensar las falencias y aciertos de los procesos pedagógicos en una comunidad determinada. Las prácticas pedagógicas suelen concebirse en el contexto de una comunidad educativa oficial, olvidando el conocimiento que se desarrolla en la cotidianidad por los agentes inmersos en procesos sociales de distinto carácter, lo cual amerita que los implicados en estos procesos cuestionen su realidad inmediata. El desarrollo de las habilidades comunicativas, partiendo de la praxis pedagógica, puede cimentar otra perspectiva del trabajo comunitario, teniendo en cuenta la necesidad de desarrollar un diálogo constructivo en el cual la teoría pueda reconciliarse con la práctica en la construcción de una sociedad democrática y participativa.
Estrategias de reproducción social, un estudio de caso sobre el currículo oculto y los guetos educativos de la política pública en el campo educativo bogotano
Authors: Reyes Pardo Daniel Fernando
Published: November 2017

La política educativa en Bogotá en las últimas décadas ha girado en torno a la inclusión y a la democratización de la educación, en principio escolar y posteriormente universitaria. Este artículo expone los análisis realizados sobre la política pública educativa: Alianza para la Educación Superior, tomando como estudio de caso una institución educativa de Bogotá, a partir de la metodología de etnografía multimodal. Se aborda el tema de la educación desde la teoría de campos, de Pierre Bourdieu, y se hace especial énfasis en la estratificación de los agentes en el campo educativo bogotano. En este contexto, se estudia la relación de la estratificación con el currículo oculto de las políticas públicas, en donde intervienen las competencias como un concepto importante en la ideología subyacente a este tipo de política, que genera unos guetos educativos distribuidos por toda la ciudad.
Negocios socialmente responsables: una propuesta ética y educativa para la vida
Authors: Torres Alape Diana
Published: November 2017

Sin resumen.
Posicionalidades brujas: hacia un activismo de espiritualidad chicana/latina
Authors: Lara Irene
Published: November 2017

Este artículo de investigación profundiza sobre las construcciones de ‘la Bruja’ —una mujer practicante de conocimientos espirituales, sexuales y curativos— en nuestro imaginario cultural contemporáneo basado en el legado de la otrerización de curanderas en Europa y las Américas. En particular, analizo la canción “‘Livin’ La Vida Loca” de Ricky Martin sobre el poder ambivalente y hechicero que una mujer racializada ejerce sobre un hombre. Este artículo explora las maneras en que las ‘bru­jas’ son temidas por su conocimiento y poder, y por lo tanto, son sometidas a tratamientos opresivos. Mi planteamiento es por una posicionalidad bruja en los estudios feministas Chicana/Latina que incluya el desarrollo de nuestras propias episte­mologías brujas. Como práctica de lo que Gloria Anzaldúa llamaría ‘activismo espiritual,’ una posicionalidad bruja compren­de curar las creencias internalizadas que demonizan la Bruja, la espiritualidad y sexualidad transgresivas que ella representa.
Entramado de violencias, efectos y alternativas de docentes y estudiantes de secundaria
Authors: Poujol Galván Guadalupe , Fracchia Figueiredo Myriam
Published: November 2017

Con la participación de docentes de una secundaria en Morelos (México) investigamos las violencias desde los diversos ámbitos de la cotidianidad de sus actores: la colonia, la familia, la escuela y el aula, así como sus efectos en el entramado de relaciones sociales involucradas. De modo que, en este artículo abordamos las formas de violencia que los sujetos viven o expresan en el contexto escolar y algunos de sus efectos sociales y educativos. En un segundo momento, presen­tamos los primeros resultados de la intervención realizada en forma de ‘acompañamiento entre pares’ orientada a bajar los niveles de deserción y de rezago escolar. Para finalizar, proponemos las escuelas basadas en “redes de cooperación social”, como un modo de enfrentar hechos estructurales y coyunturales que se sobreponen a la escuela y desde donde se construya una convivencia basada en la protección de la vida.
Problemáticas y potencialidades de las iniciativas productivas juveniles en el horizonte crítico del "estado social de derecho"
Authors: Flórez Culman Jorge Alberto
Published: November 2017

Este trabajo busca identificar las problemáticas y potencialidades de las iniciativas productivas de los jóvenes. Los campos de análisis del autor son los jóvenes como sujetos de derecho desde la Constitución de 1991 y algunas políticas públicas de juventud, los jóvenes en las dinámicas del desarrollo y organización y productividad.Para el autor los jóvenes se enfrentan a un panorama ambiguo: de un lado el reconocimiento y la apertura política y de otro la incoherencia entre el discurso de derechos y la realidad juvenil, impregnada de desempleo y falta de oportunidades. Generalmente los proyectos que se implementan para la juventud son iniciativas de corto aliento, asistenciales y centradas en problemáticas que han sido identificadas desde las instituciones que no recogen el sentir de los jóvenes. Entretanto, las producciones de los jóvenes exceden las expectativas institucionales e imprimen energía vital a sus comunidades. Sin embargo, las instituciones han sabido canalizar esa energía a sus propios intereses, razón por la cual los jóvenes prefieren obrar al margen del Estado.
El chamanismo y los ejercicios espirituales de la Grecia clásica
Authors: García Aguilar Ginna Fernanda
Published: November 2017

El texto pretende diferenciar claramente los ejercicios espirituales propios de las escuelas filosóficas griegas y las prácticas chamánicas. Para la autora la comparación entre ambos fenómenos constituye un reduccionismo en el que incurren algunos autores. El sentido de los ejercicios espirituales en la antigua Grecia consistía en la transformación de sí mismo; en una práctica pedagógica orientada a formar mejores ciudadanos dentro de un tipo de formación política y de praxis social determinada. Aunque los rituales chamánicos también están ligados al funcionamiento político de la comunidad, éstos se basan en el equilibrio entre los dioses y los hombres y se anclan más en el terreno de la búsqueda de conocimientos que operen como dispositivos de orden simbólico de las actividades de la comunidad.