bluuebunny/crossref_metadata_2025 huggingface dataset:
Taxonomy of ‘Euconnus complex’. Part XXIII. Status of Napochus Thomson, Pycnophus Casey, and Filonapochus Franz revisited (Coleoptera, Staphylinidae, Scydmaeninae)
Authors: JAŁOSZYŃSKI PAWEŁ
Published: August 2021

In previously published parts of this long-term study, subgenera Napochus Thomson and Pycnophus Casey of Euconnus Thomson were tentatively maintained, based on detailed morphological examination of their type species. Since then, many more species have been studied, including several hundred nominal Euconnus s. str., Napochus, and Pycnophus spp., and over a thousand presumably undescribed species collected on all continents. Considering character variability, current diagnoses of Napochus and Pycnophus were found to largely overlap with that of Euconnus s. str., and many species show intermediary features. In the present study, examples of such intermediary or transitional characters are illustrated, and character variability within the Euconnus s. str. + Napochus + Pycnophus morphological group is discussed. Available morphological evidence strongly supports a concept of a highly diverse Euconnus s. str. that includes Napochus and Pycnophus. Consequently, Napochus syn. n. and Pycnophus syn. n. are merged with Euconnus s. str. as junior synonyms. In addition, examination of the type specimens of the type species of Glandularia L.W. Schaufuss and Connophron Casey, both names currently treated as junior synonyms of Napochus, confirms the previously established synonymies. Characters of the previously revised subgenus Filonapochus Franz were also found to fall within the variability revealed in the present study, and also Filonapochus syn. n. is placed as a junior synonym of Euconnus s. str.
Biomechanical Response of the Human Foot Model Exposed to Vibrations: A Finite Element Analysis
Authors: Alphin M. S. , Paul Chandra Kumar J. , Tony B. Jain A. R.
Published: August 2021

Prolonged exposure to mechanical vibration has been associated with many musculoskeletal, vascular and sensorineural disorders of the foot from simple Plantar fasciitis and Achilles Tendonitis to complex ones as Tarsal tunnel syndrome (TTS) and Vibration white feet/toes. Foot-transmitted
vibrations (FTV) are exposed to the occupants using vibrating equipment’s or standing on vibrating platforms. Prolonged exposure to foot-transmitted vibrations (FTV) can lead to syndromes like vibration white feet/toes may result in tingling sensation, blanching of the toes and even
numbness in the feet and toes. A multi-layered two dimensional, plane strain finite element model is developed from the actual cross-section of the human foot to study the stresses and strains developed in the skin and soft tissues. The foot is assumed to be in contact with a steel plate,
mimicking the interaction between the foot and the work platform. The skin and the subcutaneous tissue are considered as hyperelastic and viscoelastic. The effects of loading in the form of displacements and the frequency of sinusoidal vibration on a time-dependent stress/strain distribution
at various depths in the subcutaneous tissue of the foot are investigated. The simulations indicate that lower frequency vibrations penetrate deep into the subcutaneous tissue while higher frequencies are concentrated in the outer skin layer. The present biomechanical model may serve as a
valuable tool to study the response of foot of those who work on a vibrating platform.
Remifentanil Suppresses Oxidative Stress and Inflammation Induced by Glutamate via Activation of PPARγ/HO-1 Signaling Pathway in Hippocampal Neuronal Cells
Authors: Liu Weihua , Wang Xinli , Du Liangqin , Sun Yanlin
Published: August 2021

Excitotoxicity caused by glutamate severely damages the central nervous system, contributing to the progress of neurodegenerative diseases. Remifentanil is an ultra-short acting syntheticα-opioid receptor agonist and it protects the body against oxidative stress. Oxidative stress is a causative factor for neuronal cell death, contributing to the pathogenesis of neurological diseases. More importantly, remifentanil has been confirmed to have neuroprotective effects on cerebral ischemia. Hence, the aim of the present study was to investigate the molecular mechanism underlying the effect of remifentanil on glutamate (Glu)-induced oxidative stress and inflammation in hippocampal cells. In present study, the cell viability was detected via CCk-8 assay. The cell apoptosis was evaluated by tunel assay. Western blot was performed for measurement of protein expression level. Generation of ROS level was detected by the ROS Activity Assay Kit (KA3842, Abnova) and DCF-DA staining method. MDA and SOD levels were detected by corresponding kits. The results from the present study suggested that remifentanil enhanced cell viability, reduced cell apoptosis rate and prevented oxidative stress in glutamate-induced HT22 cells. The PPARγ/HO-1 pathway was activated by remifentanil. After inhibition of PPARγ/HO-1 pathway, the anti-apoptosis and anti-oxidative stress effects of remifentanil were abolished. In conclusion, remifentanil has anti-apoptosis and anti-oxidative stress effects on glutamate-induced HT22 Cells via PPARγ/HO-1 pathway. Hence, remifentanil is a promising agent for attenuation of cytotoxicity induced by glutamate, providing a new strategy for treatment of excitotoxicity caused by glutamate in the central nervous system.
Research on Mechanism of miRNA-22 Related with Hepatocellular Carcinoma Metastasis for Regulating Process of Tumor Protein P53
Authors: Pan Gang , Xiao Min
Published: August 2021

The action of miRNA-22 related with HCC metastasis was analyzed in our study and the mechanism of miRNA-22 related with HCC metastasis was discussed. The HCC hep2 cell was transfected with miRNA-22 mimics and miRNA-22 NC instantaneously followed by analysis of cell migration by Transwell
assay, cell viability by MTT and clone formation and cell apoptosis by flow cytometry. The action of miRNA-22 mimics and miRNA-22 on the expression of P53 mRNA in HCC Hep2 cell was detected by RT-PCR. The cell activity in miRNA-22 mimics group was significantly elevated compared with miRNA-22
NC group (P < 0.01). Meanwhile, the apoptotic rate, migrated and invaded capacity of HCC cell was significantly elevated (P < 0.01). The expression level of P53 mRNA was reduced (P < 0.01). In conclusion, overexpression of miRNA-22 could restrain the apoptosis
of HCC hep2 cell and down-regulated the expression of P53 so as to prompt cell invasion capacity.
MiR-375 Enriched in Bone Marrow Mesenchymal Stem Cells (BMSC) Exosomes Inhibits Prostate Cancer Cell Migration and Invasion by Down-Regulating Trefoil Factor 3 (TFF3)
Authors: Liang Qihong , Zhong Wei
Published: August 2021

To study the effect and mechanism of miR-375 enriched in BMSC exosomes on prostate cancer (PC) cells. Bioinformatics assessed the potential regulatory miRNA of TFF3 and miR-375 level in breast cancer cells and breast cancer clinical samples was detected by PCR. Dual luciferase assay
validated the relationship between TFF3 and miR-375. miR-375 mimics or sh-TFF3 was transfected into PC cells, followed by measuring miR-375 and TFF3 by PCR and Western-blot. Cell proliferation, invasion, migration and apoptosis by Edu staining, transwell and flow cytometry. The BMSC exosomes
were then isolated and co-cultured with PC cells to detect cell proliferation and invasion. PC cells and tissues showed the expression of miR-375 was decreased, indicated that miR-375 specifically inhibited TFF3 level. miR-375 was enriched in MSC-derived exosomes and could be transferred to
PC cells. miR-375 mimics, exosome miR-375 or silenced TFF3 inhibited TFF3 level, up-regulated PCNA, MMP-2/9 expression, thereby inhibiting cell proliferation and metastasis, and promoting cell apoptosis. miR-375 is enriched in BMSC exosomes and inhibits PC cell migration and invasion by reducing
TFF3.
Mechanism of miR-506 Targeting Autophagy and Apoptosis-Associated Gene Beclin1 to Promote Bone Marrow Mesenchymal Stem Cells (BMSCs) Differentiation and Metastasis to Breast Cancer
Authors: Liu Qiumei , Wu Yanyan , Ye Jian
Published: August 2021

This study investigates miR-506 targeting the autophagy and apoptosis-related gene Beclin1 and analyzes the mechanism of its effect on bone marrow mesenchymal stem cells (BMSCs) differentiation and metastasis to breast cancer. Detection of miRNA-506 expression in BMSCs and breast cancer
cells was done by Real-time PCR. A luciferase reporter system analyzed the targeting relationship between Beclin1 and miR-506. miR-NC group, BMSCs induction group, siRNA-NC group, and siRNA-Beclin1 group was set to measure Beclin1 expression, cell differentiation and migration by transwell
assay, cell viability by MTT assay, proliferation by EdU staining and apoptosis and cycle by flow cell assay. miRNA-506 showed a high expression in breast cancer cells and low expression in BMSCs. miRNA-506 mimics significantly promote breast cancer cell proliferation which was inhibited by
miRNA-506 inhibitors. The expression of Beclin1mRNA was significantly higher and miR-506 was lower in breast cancer cells. BMSCs induction significantly downregulated Beclin1 expression, increased miR-506 expression, and promoted cell invasive differentiation and metastatic capacity. In conclusion,
elevated miR-506 expression was associated with decreased Beclin1 expression and increased metastatic differentiation capacity of breast cancer cells, which could effectively increase differentiation capacity and metastatic differentiation after induction by BMSCs.
Is there any improvement in simulation of wintertime Western Pacific teleconnection pattern and associated climate anomalies in CMIP6 comparing with CMIP5 models?
Authors: Aru Hasi , Chen Wen , Chen Shangfeng
Published: August 2021

The western Pacific pattern (WP) is one of the most important atmospheric teleconnections over the Northern Hemisphere (NH) in boreal winter, which plays key roles in regulating weather and climate variations over many parts of the NH. This study evaluates ability of the coupled models participated in CMIP5 and CMIP6 in capturing the spatial pattern, dominant frequency, and associated climate anomalies of the winter WP. Ensemble means of the CMIP5 and CMIP6 models well capture spatial structures of the WP, with slightly higher skills for the CMIP6. However, the northern (southern) centre of the WP is shifted westward (eastward) relative to the observations, and the strength of the northern centre is overestimated in most CMIP5 and CMIP6 models. CMIP6 shows an improvement in simulating the dominant periodicity of the WP. WP-related climatic anomalies in most parts of the NH can be well simulated. However, there exists a large spread across the models in simulating surface air temperature (SAT) anomalies in Russian Far East and Northwest North America, which is attributable to the diversity of the intensity of the WP’s northern lobe. Most CMIP5 and CMIP6 models largely overestimate the WP-related precipitation anomalies over Siberia, which is partly due to the overestimation of mean precipitation there. Furthermore, most models simulate a close relation of the WP and Arctic Oscillation (AO), which does not exist in observation. The CMIP5 and CMIP6 models with weak WP-AO relations have better ability than the models with strong WP-AO relations in capturing the WP-related SAT and precipitation anomalies over the NH, especially over Eurasia.
Mechanism for Southward Shift of Zonal Wind Anomalies During the Mature Phase of ENSO
Authors: Gong Yuhan , Li Tim
Published: August 2021

The cause of southward shift of anomalous zonal wind in the central equatorial Pacific (CEP) during ENSO mature winter was investigated through observational analyses and numerical model experiments. Based on an antisymmetric zonal momentum budget diagnosis using daily ERA-Interim data, a two-step physical mechanism is proposed. The first step involves advection of the zonal wind anomaly by the climatological mean meridional wind. The second step involves the development of an antisymmetric mode in the CEP, which promotes a positive contribution to the observed zonal wind tendency by the pressure gradient and Coriolis forces. Two positive feedbacks are responsible for the growth of the antisymmetric mode. The first involves the moisture–convection–circulation feedback, and the second involves the wind–evaporation–SST feedback. General circulation model experiments further demonstrated that the boreal winter background state is critical in generating the southward shift, and a northward shift of the zonal wind anomaly is found when the same SST anomaly is specified in boreal summer background state.
Tourists’ perceptions of climate: Application of machine learning to climate and weather data from Chinese social media
Authors: Tao Y G. , Zhang F. , Liu W J. , Shi C Y.
Published: August 2021

Understanding tourists’ perceptions of climate is essential to improving tourist satisfaction and destination marketing. This paper constructs a sentiment analysis framework for tourists’ perceptions of climate using not only continuous climate data but also short-term weather data. Based on Sina Weibo, we found that Chinese tourists’ perceptions of climate change were at an initial stage of development. The accuracies of word segmentation between sentiment and nonsentiment words using ROST CM, BosonNLP, and GooSeeker were all high, and the three gradually decreased. The positively expressed sentences accounted for 79.80% of the entire text using ROST EA, and the sentiment score was 0.784 at the intermediate level using artificial neural networks. The results indicate that the perceived emotional map is generally consistent with the actual climate and that cognitive evaluation theory is suitable to study text on climate perception.
Prediction of preeclampsia using a combination of serum micro RNA-210 and uterine artery Doppler ultrasound
Authors: Trongpisutsak Ananya , Phupong Vorapong
Published: August 2021

The objective was to determine whether a combination of serum micro RNA-210 level and uterine artery Doppler can predict preeclampsia in pregnant women at 16–24 weeks gestation. A prospective observational study conducted in singleton pregnant women at 16–24 weeks of gestation who had prenatal care at the King Chulalongkorn Memorial Hospital, Department of Obstetrics and Gynecology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand between 2017 and 2018. Uterine artery Doppler ultrasound and blood testing for serum micro RNA-210 were performed. Pregnancy outcomes were recorded. Optimal cut-off for uterine artery pulsatility index (PI) and serum micro RNA-210 were obtained to calculate the predictive values for preeclampsia. Data from 443 participants were analyzed. Twenty-two cases developed preeclampsia (5.0%) and seven of these preeclamptic cases had early-onset preeclampsia (1.6%). Pregnant women with preeclampsia had higher mean PI of the uterine artery (1.34 ± 0.52 vs 0.98 ± 0.28, p = 0.004), higher detection rates of diastolic notching (45.5% vs 11.2%, p < 0.001), and lower median serum micro RNA-210 level (22.86 vs 795.78, p < 0.001) than pregnant women without preeclampsia. Using abnormal serum micro RNA-210 level, abnormal mean PI or uterine artery diastolic notches to predict for preeclampsia, the sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) were 95.5%, 54.9%, 10.0%, and 99.6%, respectively. For early-onset preeclampsia prediction, the sensitivity, specificity, PPV, and NPV were 100.0%, 53.2%, 3.3%, and 100.0%, respectively. This study demonstrated that a combination of serum micro RNA-210 and uterine artery Doppler is effective in predicting preeclampsia in the second trimester.
Proactively Pivot: Guidance on Adapting the PBIS Framework in Response to Crises to Support Students With Disabilities
Authors: Clemens Katharine , Borowski Luke , Donovan Mary , Meyer Katherine , Dooley Kathryn , Simonsen Brandi
Published: August 2021

Schools that employ evidence-based multi-tiered system of supports (MTSS) frameworks, like Positive Behavioral Interventions and Supports (PBIS), invest in core system, data, and practice features to support students, families, and educators. A strong framework enables settings to enhance and adjust their implementation to meet the needs of all students, including students with disabilities, in a range of contexts. Importantly, as schools pivoted among remote, hybrid, and in-person learning modes throughout 2020 and 2021, effective leadership teams used their PBIS framework to successfully navigate these transitions. Based on lessons learned during this period, we present three key recommendations to adapt implementation in response to crises: (1) leverage existing systems, (2) use data to guide decision-making, and (3) pivot practices. To illustrate these recommendations, we describe PBIS implementation in an alternative setting supporting students with disabilities and share examples of how educators used the PBIS framework to meet the challenges presented by new contexts.
Effect of test parameters on the stability of fabric shape retention indexes increase recovery testing
Authors: Tang Qianhui , Wang Lei , Gao Weidong , Pan Ruru
Published: August 2021

Fabric shape retention is a crucial property that impacts the durability and usability of fabric and which needs a convenient and accurate evaluation method. In the previous research, the automated crease recovery testing method was used to obtain fabric crease recovery information and evaluate the property of shape retention. Based on the previous research, an orthogonal test method was adopted to investigate the effect of different test parameters on the stability of shape retention detection in this paper. First, three factors, that of sample size, pressure, and pressure time, and three different levels of each factor were determined by the L9(34) orthogonal test table. Next, the fabric shape retention indexes were detected by nine different test schemes, and the comprehensive score of shape retention index standard deviation was obtained as the evaluation criterion of the orthogonal test results. Finally, the optimal test scheme was determined by visual analysis and variance analysis. The results show that the sample size has a certain effect on the stability of shape retention indexes, while the pressure time and the pressure have no significant influence. The optimal test scheme is that the sample size is 30 cm × 30 cm, the pressure time is 60 s, and the pressure is 40 N. The test result measured by the optimal test parameters reveals excellent stability when the vertex angle standard deviation is 2.0°, the height standard deviation is 0.06 cm, and the shape retention area standard deviation is 0.16 cm2. This paper provides an experimental basis for improving the accuracy of fabric shape retention evaluation method.
Effect of alkaline and benzoyl chloride treatments on the mechanical and morphological properties of sugar palm fiber-reinforced poly(lactic acid) composites
Authors: Sherwani SFK , Sapuan SM , Leman Z , Zainudin ES , Khalina A
Published: August 2021

The present study deals with the effects of alkaline and benzoyl chloride treatments of sugar palm fibers (SPFs) on the mechanical and morphological properties of SPF-reinforced poly(lactic acid) (PLA) composites. Seven different parameters of SPFs were compared, which were untreated, three alkaline solution concentrations of 4%, 5%, and 6% for alkaline treatment, and 50 ml benzoyl chloride-treated SPFs at three different soaking durations of 10, 15, and 20 min. Composites of 30 wt.% SPF–reinforced 70 wt.% PLA were prepared by using a Brabender plastograph mixer and a hot press. The tensile, flexural, and impact properties of the SPF/PLA composites were improved after alkaline and benzoyl chloride treatments on the SPFs. However, the best tensile, flexural, and impact properties of the composites were observed at 6% alkaline treatment of SPF; the morphological analysis also supported this. The 6% alkaline treatment of the SPF/PLA composite demonstrated the highest tensile, flexural, and impact strength values of 17.08 MPa, 32.34 MPa, and 4.39 kJ/m2, respectively. These treated SPF/PLA composites could be appropriate for automobile component applications.
Delivering higher density suburban development: The impact of building design and residents’ attitudes
Authors: Navarrete-Hernandez Pablo , Mace Alan , Karlsson Jacob , Holman Nancy , Zorloni Davide Alberto
Published: August 2021

The urgent need for housing in London will be met almost exclusively through building on brownfield sites. While Inner and suburban Outer London are both home to a range of brownfield sites, the politics of delivering new housing varies between the two. First, Outer London is built at significantly lower density and therefore densification has a more noticeable impact. Second, many residents in Outer London value living at lower density and will see densification as undermining that which they value. Third, homeownership is more common in Outer London and as housing is the most significant asset for most homeowners any threat to its value is likely to be strongly resisted. Our research tests whether design can positively impact both the perception and acceptability of densification. For this, we run a randomised control trial presenting 939 Outer London residents with simulated images representing different design features. We find that the effects of building design are limited and relate almost exclusively to low and medium density options. Our research shows that vernacular design can make some increase in density acceptable but for significantly higher density the influence of design declines. As density increases, the perception and acceptability of density are more influenced by people’s views on, for example, the extent of London’s housing crisis. This indicates that planners and politicians must reach beyond design and seek to better inform and persuade residents about housing need if the impasse on densification is to be overcome.
Do Sideline Tests of Vestibular and Oculomotor Function Accurately Diagnose Sports-Related Concussion in Adults? A Systematic Review and Meta-analysis
Authors: Harris Sarah A. , Dempsey Alasdair R. , Mackie Katherine , King Doug , Hecimovich Mark , Murphy Myles C.
Published: August 2021

Background:

Sports-related concussion (SRC) assessment tools are primarily based on subjective assessments of somatic, cognitive, and psychosocial/emotional symptoms. SRC symptoms remain underreported, and objective measures of SRC impairments would be valuable to assist diagnosis. Measurable impairments to vestibular and oculomotor processing have been shown to occur after SRC and may provide valid objective assessments.

Purpose:

Determine the diagnostic accuracy of sideline tests of vestibular and oculomotor dysfunction to identify SRC in adults.

Study Design:

Systematic review; Level of evidence, 4.

Methods:

Electronic databases and gray literature were searched from inception until February 12, 2020. Physically active individuals (>16 years of age) who participated in sports were included. The reference standard for SRC was a combination of clinical signs and symptoms (eg, the Sport Concussion Assessment Tool [SCAT]), and index tests included any oculomotor assessment tool. The QUADAS tool was used to assess risk of bias, with the credibility of the evidence being rated according to GRADE.

Results:

A total of 8 studies were included in this review. All included studies used the King-Devick test, with no other measures being identified. Meta-analysis was performed on 4 studies with a summary sensitivity and specificity of 0.77 and 0.82, respectively. The overall credibility of the evidence was rated as very low.

Conclusion:

Caution must be taken when interpreting these results given the very low credibility of the evidence, and the true summary sensitivity and specificity may substantially differ from the values calculated within this systematic review. Therefore, we recommend that clinicians using the King-Devick test to diagnose SRC in adults do so in conjunction with other tools such as the SCAT.

PROSPERO Registration:

CRD42018106632.
It Takes a Tiny House Village: A Comparative Case Study of Barriers and Strategies for the Integration of Tiny House Villages for Homeless Persons in Missouri
Authors: Evans Krista
Published: August 2021

Although interest in addressing homelessness with tiny house villages continues to grow, they face numerous barriers, from land use laws to resident concerns about homeless populations. This research examines such barriers, in addition to strategies for the integration of such developments. The study finds that it is important that tiny house villages for homeless residents address potential not-in-my-backyard (NIMBY) concerns. However, the study also finds that there are strategies and enabling factors which facilitate the integration of these developments. The study has resulted in the establishment of strategies for integrating tiny house villages for the homeless into communities.
Effect of a novel healthcare leadership program on leadership and emotional intelligence
Authors: Bonazza Nicholas A. , Cabell Grant H. , Cheah Jonathan W. , Taylor Dean C.
Published: August 2021

The purpose of this study was to assess the effectiveness of the Feagin Leadership Program (FLP) in teaching leadership domains and emotional intelligence. An anonymous survey of 178 graduates of FLP (2011–2019) including the Trait Emotional Intelligence Questionnaire-Short Form (TEIQue-SF) was used to assess emotional intelligence and program views. ANOVA was used to compare the difference in emotional intelligence domains between groups. Respondents reported the FLP most improved skills in communication, emotional intelligence, and team building. Medical students (18, 38.3%) and faculty/staff (5/14, 35.7%) reported the most relevant domain was emotional intelligence; residents/fellows reported the most relevant domain was teamwork (8/37, 21.6%). Respondents in residency/fellowship had the highest score in emotionality (P = .01). These results suggest that a healthcare leadership program tailored to medical trainees was effective in improving their competency in various leadership domains, and that emotional intelligence and teamwork were the most relevant components of the program.
In vitro evaluation of delamination resistance of PEEK and CFR-PEEK
Authors: Sakoda Hideyuki , Uematsu Miyuki , Okamoto Yoshihiro , Haishima Yuji
Published: August 2021

Poly-ether-ether-ketone (PEEK) and carbon fiber reinforced PEEK as orthopedic implant materials exhibit excellent material properties. Although delamination of PEEK materials has been reported in knee joint wear research, the delamination resistance behavior remains unclear. In this study, the delamination resistance of PEEK materials was investigated; these materials were compared to ultra-high molecular weight polyethylene (UHMWPE). The results of a ball-on-flat type delamination test indicated that the PEEK materials underwent delamination considerably earlier than UHMWPE, and the contact area of the PEEK materials was smaller than that of UHMWPE. Moreover, the indentation modulus, hardness, and coefficient of friction were higher for PEEK materials than for UHMWPE. The reduced tendency of PEEK materials to undergo deformation to mitigate stress concentration at low conformity contact conditions contributed to their inferior delamination resistance compared to that of UHMWPE. The delamination resistance of the PEEK materials was equivalent to that of degraded UHMWPE, which highlights the risk of delamination of PEEK implants in a clinical context. Consequently, when using PEEK materials as an implant component loaded at a low conformity contact condition, the material selection and component design must be carefully considered. Overall, the results of this study can help guide the future development of PEEK-based implants.
The value of participatory urban policy councils: engaging actors through policy communities
Authors: Pimentel Walker Ana Paula , Friendly Abigail
Published: August 2021

Despite considerable literature exploring Brazil’s participatory management, less academic attention focuses on Brazil’s public policy councils ( conselhos gestores de políticas públicas), which are permanent political-institutional structures on a range of policy issues mediating between society and the state. This article analyses urban policy councils in Porto Alegre, Rio Grande do Sul State, and Niterói, Rio de Janeiro State, considering whether this participatory planning tool advances democratic inclusion. We approach participatory planning through the lens of policy communities. Through these cases, we demonstrate that these two councils do not, in fact, enable all those affected and interested to influence and define policies. Yet even if the views of the most disenfranchised do not ultimately prevail, these urban policy councils contribute to publicizing urban policy issues and democratizing the range of stakeholders that gain access to the policy community. We conclude by highlighting suggestions for improving public policy councils as mechanisms for participatory planning.
An assessment of psychological distress and professional burnout in mental health professionals in Australia during the COVID-19 pandemic
Authors: Northwood K , Siskind D , Suetani S , McArdle PA
Published: August 2021

Objective:

To examine psychological distress and professional burnout in a cohort of Australian mental healthcare workers during the COVID-19 pandemic

Methods:

This study examined a multi-disciplinary cohort of mental healthcare workers in a large metropolitan service in Australia. Demographic information as well as information on employment and individual’s personal experience of the COVID-19 pandemic was collected and correlated with cross-sectional assessments of anxiety, depression and professional burnout using validated clinical questionnaires

Results:

Mental healthcare workers reported high levels of anxiety, depression, and professional burnout. Participants reported some reduction in anxiety since the early phases of the pandemic, but the reduction was more modest in mental healthcare workers identifying as being “vulnerable” employees.

Conclusion:

Despite the low numbers of COVID-19 cases, mental healthcare workers in Australia report significant levels of psychological distress and professional burnout during the pandemic.
Encephalopathy caused by Talisia esculenta intoxication in pregnant ewes and their newborn lambs
Authors: Almeida Valdir M. , Silva-Filho Givaldo B. , Bom Hisadora A. S. C. , Fonseca Silvio M. C. , Riet-Correa Franklin , Uzal Francisco A. , Woolard Kevin D. , Souza Francisco A. L. , Mendonça Fábio S.
Published: August 2021

An outbreak of acute encephalopathy occurred in pregnant ewes and their newborn lambs associated with consumption of Talisia esculenta fruits and bark. Clinical signs in 5 adult pregnant ewes included drooling, bloat, tachypnea, depression, ataxia, body shaking, difficulty in rising, and recumbency. Three neonatal lambs born to some of those ewes had similar clinical signs. No significant gross abnormalities were observed on autopsy. Histologically, neuronal necrosis, axonal and dendritic swelling, and loss of Purkinje neurons were observed in the cerebellum. The observation of similar neurologic clinical signs and lesions in pregnant ewes and their neonatal lambs suggests that the toxic principle of T. esculenta crosses the placenta and reaches the fetus.
NIOSH Responds to the U.S. Drug Overdose Epidemic
Authors: Osborne Jamie C. , Chosewood L. Casey
Published: August 2021

The United States is experiencing an evolving and worsening drug overdose epidemic. Although the rate of drug use among workers has remained relatively stable, the risk of overdose and death among drug users has not, as illicit drugs have increased in potency and lethality. The cumulative impacts of COVID-19 and the opioid crisis increase the likelihood of illness and death among workers with opioid use disorder. Workplaces represent a critical point of contact for people living in the United States who are struggling with or recovering from a substance use disorder, and employment is a vital source of recovery “capital.” The benefits of addressing substance use in the workplace, supporting treatment, and employing workers in recovery are evident. The National Institute for Occupational Safety and Health has published research to inform policy and practice toward prevention efforts and has developed accessible resources and toolkits to support workers, employers, and workplaces in combatting the opioid overdose crisis and creating safer, healthier communities.
Latino Families’ Decisions to Accept Hospice Care
Authors: Beltran Susanny J.
Published: August 2021

Objectives:

The underrepresentation of Latinos in hospice care is well-documented. A gap remains, however, in the literature’s description of the factors that shape Latino families’ decisions to enroll in hospice care. The need for such understanding is dire considering the shifts in population and the research evidence that Latinos experience worse end-of-life outcomes compared to non-Latino whites. This study contributes to such understanding by exploring Latino older adults’ experiences with healthcare broadly and reasons for choosing hospice care specifically, including how they learned about hospice and their understanding of the service at the time of enrollment.

Methods:

Semi-structured interviews were conducted with 13 hospice-enrolled Latinos 65 or older, or their decision-making proxies. Qualitative data was analyzed using thematic analysis.

Results:

Findings show that hospice represents a way to access services, and not necessarily a philosophy of care that Latinos understand or seek at end of life.

Conclusion:

Healthcare providers such as hospital and hospice social workers must engage in efforts to enhance advance care planning discussions and hospice education with the Latino community.
Learning in Times of COVID: Journalism Education in Kashmir, India
Authors: Pain Paromita , Ahmed Aaliya , Zahra Khalid Malik
Published: August 2021

Our in-depth qualitative interviews with journalism graduate students and professors, from Kashmir, India, show that unlike the rest of India, the region experienced extremely low internet connectivity, and this combined with a lack of access to technology nearly brought classes to a standstill. But students and teachers, used to social disruptions, used the COVID-19 pandemic to learn and practice journalism that was deeply bound to the community and they created “circles of trust” that helped them overcome internet and other technical issues. Ramifications for journalism education in situations of low connectivity and poor technology resources are discussed.
Emerging application of Google Trends searches on “conjunctivitis” for tracing the course of COVID-19 pandemic
Authors: Pellegrini Marco , Ferrucci Edoardo , Guaraldi Fabio , Bernabei Federico , Scorcia Vincenzo , Giannaccare Giuseppe
Published: August 2021

Purpose:

The aim of the present study was to use Google Trends for evaluating the association between the internet searches of the term “conjunctivitis” and the daily new cases of COVID-19.

Methods:

The relative search volume (RSV) of conjunctivitis from January 1 to April 16, 2019 (control group), January 1 to April 16, 2020 (first wave), and October 1 to December 31, 2020 (second wave) was obtained using Google Trends in Italy, France, United Kingdom, and United States. The number of COVID-19 daily new cases in the same countries were retrieved from Worldometer. Lag time correlation analyses were performed to evaluate the relationship between RSV and daily new cases (Pearson’s correlation coefficient).

Results:

During the first wave, the lagged RSV of conjunctivitis was significantly correlated with the number of COVID-19 daily new cases in all investigated countries. The highest correlation coefficients were obtained with a lag of 16 days in Italy ( R = 0.868), 18 days in France ( R = 0.491), 15 days in United Kingdom ( R = 0.883), and 14 days in United States ( R = 0.484) (all p < 0.001). Conversely, no significant correlations were found in the second wave and in the control group.

Conclusion:

Google Trends searches on conjunctivitis were significantly correlated with COVID-19 daily new cases during the first wave in Italy, France, United Kingdom, and United States, with a lag of 14–18 days. Repeating the analysis for the second wave, however, no significant correlations were found in any of the investigated countries.
Yokozuna Hakuhō—Japanese Mongolian hero
Authors: Bar-On Cohen Einat
Published: August 2021

Yokozuna Hakuhō, a prominent Sumo wrestler, is a Mongolian-born Japanese national hero. However, he, as other Mongolian wrestlers, presents Sumo with tensions between worldviews, which are battled both within the hierarchical setting of the Sumo association, and in public opinion. Those concern questions of etiquette and ethical behavior, between what is understood the “real Japanese” spirit, and the Mongolian attitude. Moreover, the Mongolian attitude also coincided with modern tendencies and the culture of celebrities so that those tensions are also a case of a Japanese way of dealing with the external influences of globalization. Moreover, since both Japanese and Mongolian cosmos are “inclusive,” namely, tend toward the non-dual, the tensions are not resolved but rather create a cultural enclave of shifting assemblages yielding both new regulations and popular opinions. And while those tensions are negotiated, the common belief as to what constitutes true Japanese traits is also forged and inculcated.
Toward temporally complex collaboration in an interorganizational research network
Authors: Jarvenpaa Sirkka L , Välikangas Liisa
Published: August 2021

Prior research suggests interorganizational collaboration faces temporal challenges and also opportunities yet is scarce on the role of time enabling—more often deterring—collaboration for collective benefit. Our contribution is highlighting how a large industry–academic research network developed temporally complex collaboration through varying temporal rules and relationships. The three network-developed collaborative repertoires, with their particular temporal rules and relationships, complemented the externally imposed calendar repertoire: (1) sprint repertoire, following a familiar agile method for joint research, (2) narrative time repertoire, enabling sharing research results across various events at the program level, and (3) “right” time repertoire that turned research results into action in emerging business ecosystems. With these collaborative repertoires, both the temporal diversities of home organizations and the asynchronies of the network activities were resolved for collective benefit. We contribute to the intersection of the literatures on interorganizational network collaboration and temporality.
Application of force-monitor ultrasonography to assess distal radioulnar joint instability in patients with triangular fibrocartilage complex injury
Authors: Yuine Hiroshi , Yoshii Yuichi , Iwai Koichi , Ishii Tomoo , Shiraishi Hideki
Published: August 2021

Introduction

In this study, we evaluated the differences and measurement accuracy in the force–displacement relationship of the distal radioulnar joint (DRUJ) between patients with triangular fibrocartilage complex (TFCC) injury and healthy controls using force-monitor ultrasonography.

Methods

This study included 11 TFCC injury patients and 22 healthy controls. We evaluated differences in the force–displacement relationship of the DRUJ in these patients using force-monitor ultrasonography. Cyclic compression was applied to the dorsal surface of the ulnar head. Distance between the dorsal surface of the distal radius and ulnar head at the DRUJ level was measured in the initial and pressed-down positions. Changes in radioulnar displacement, applied force, and displacement-to-force ratio were measured. Furthermore, we compared the parameters between the affected and unaffected wrists and between TFCC injury patients and controls.

Results

The radioulnar displacement and displacement-to-force ratio were significantly larger in the affected wrists than in the unaffected wrists ( P =  0.003 and P =  0.02). The affected/unaffected side ratio of radioulnar displacement and displacement-to-force ratio were significantly larger in the TFCC injury patients than in the controls ( P =  0.003 and P =  0.02). The area under the curve was 0.82 for the affected/unaffected ratio of the radioulnar displacement. The optimal cutoff value indicated by the receiver-operating characteristic curve for the affected/unaffected ratio of the radioulnar displacement was 1.71; the sensitivity and specificity were 82% and 86%, respectively.

Conclusions

Assessing the DRUJ instability with force-monitor ultrasonography may help identify TFCC-injured wrists.
Wolf–Hirschhorn syndrome candidate 1 facilitates alveolar macrophage pyroptosis in sepsis-induced acute lung injury through NEK7-mediated NLRP3 inflammasome activation
Authors: Liu Caixia , Cai Benlong , Li Dan , Yao Yuan
Published: August 2021

Sepsis is a complex clinical syndrome with high incidence and mortality. Acute lung injury (ALI) is a common complication of sepsis. At present, there is no effective therapeutic strategy to treat ALI. The SET domain–containing histone methyltransferase Wolf–Hirschhorn syndrome candidate 1 (WHSC1) regulates cancer progression, while its role in sepsis-induced ALI remains unclear. Thus, this study aimed to study the effect of WHSC1 on sepsis-induced ALI and to explore the potential mechanism of action. In the study, LPS treatment induced lung injury. WHSC1 was highly expressed in LPS-induced ALI. Knockdown of WHSC1 attenuated LPS-induced ALI and pyroptosis in vivo. Besides, knockdown of WHSC1 attenuated LPS-induced alveolar macrophage pyroptosis in vitro. Furthermore, NIMA-related kinase-7 (NEK7) expression could be regulated by WHSC1, and NEK7 bound to NLRP3 in alveolar macrophages. Moreover, WHSC1 regulated alveolar macrophage pyroptosis through modulating NEK7-mediated NLRP3 inflammasome activation. In conclusion, WHSC1 was highly expressed in LPS-induced ALI. WHSC1 facilitated alveolar macrophage pyroptosis in sepsis-induced ALI through NEK7-mediated NLRP3 inflammasome activation. WHSC1 may be a valuable target for the therapy of sepsis-induced ALI.
The influence of the setup shape of a portable UWB system’s antennas in sport
Authors: Pino-Ortega José , Gantois Petrus , Méndez Amaia , Rico-González Markel
Published: August 2021

Ultra-wide band (UWB) technology has become one of the most promising technologies of the future. It seems that the positioning of the antenna set influences the accuracy of the player’s performance. This study was aimed to assess the influence of two different antenna positioning system shapes: (i) octagonal installation and (ii) circular installation. A UWB technology was used to track a healthy and well-trained athlete’s (age: 38 years, mass: 76.34 kg, and height: 1.75 m) positioning. Overall, the data measured showed high accuracy in both shape setups in all trajectories assessed in static and dynamic conditions for all speed thresholds. However, the distance covered during jogging and sprinting showed poor accuracy for both shape setups. Moreover, the data measured showed high test-retest reliability and inter-device agreement in the static condition, regardless of the antenna setup shape. In conclusion, both the octagonal and circular antenna setup shape provided accurate data, but the measurement error associated within the setup shape seemed slightly different between the two systems.
Delays in Diagnosis and Treatment of Bacterial Meningitis in NYC: Retrospective Cohort Analysis
Authors: Torres Sarah D. , Kim Carla Y. , Das Mitashee , Ankam Jyoti V. , Luche Nicole , Harmon Michael , Schorr Emily M. , Glassberg Brittany , Morse Stephen S. , Weiss Don , Gofshteyn Jacqueline S. , Yeshokumar Anusha K. , Thakur Kiran T.
Published: August 2021

Community-acquired bacterial meningitis (CABM) morbidity and mortality remains high in those infected. Rapid diagnosis and treatment is paramount to reducing mortality and improving outcome. This retrospective cohort study aims to assess the time from presentation to diagnosis and treatment of vaccine preventable CABM as well as identify possible factors associated with delays in diagnosis and antibiotic administration. A retrospective chart review was conducted of individuals who presented to Columbia University Irving Medical Center (CUIMC), Children’s Hospital of New York (CHONY), Mount Sinai Medical Center, and Weill Cornell Medical Center with BM due to Haemophilus influenzae type B, Streptococcus pneumoniae, and Neisseria meningitidis between January 1, 2012 and December 31, 2017. Diagnosis was delayed by more than 8 hours in 13 patients (36.1%) and 5 individuals (13.9%) had a delay of 4 hours or more from presentation to the administration of antibiotics with appropriate CNS coverage. All of these patients were also initially misdiagnosed at an outpatient clinic, outside hospital, or emergency department. This retrospective study identified febrile and/or viral infections not otherwise specified and otitis media as the most common misdiagnoses underlying delays from presentation to diagnosis and to antibiotic treatment in those with BM.
Ileal Atresia in a 10-day-old male baby: A case report
Authors: Mrindoko Philip , Mselle Mathew , Meleki Elton , Kimambo Elise , Mchaile Deborah , Lodhia Jay
Published: August 2021

Ileal Atresia is noted to be the commonest cause of intestinal obstruction in neonates worldwide but still under diagnosed in Sub-Saharan countries with scarce data reported on its occurrence. It is likely under diagnosed due to low index of suspicion. Advancement in foetal ultrasound during prenatal period will increase index of suspicion and hence early diagnosis and correction. This is the first case report in our setup highlighting this condition. We present a case of a 10-day-old male baby referred to us due to vomiting since birth. Clinically was in distress with a palpable supraumbilical mass that was firm and non-tender. Abdominal ultrasound scan showed poor peristalsis and minimal dilation of bowels suggestive of partial intestinal obstruction. Abdominal X-ray showed dilated bowels with multiple air-fluid levels, empty rectum with features suggestive of intestinal obstruction. Patient was successfully operated but unfortunately on day 3 post-surgery succumbed.
Net national metabolism as a fine-scale metric of energetic biophysical size in an industrialised country
Authors: Eriksson Fredrik A. A. , Owen Anne , Malhi Yadvinder
Published: August 2021

The biophysical magnitude of global human economic activity is arguably the defining feature and challenge of the Anthropocene, leading to multiple environmental consequences. Quantifying this magnitude at sufficient resolution remains a challenge. We define and present the first detailed district-level analysis of Net National Metabolism (NNM) – a social metabolism energy metric – for an industrialised country (the United Kingdom), using data on household energy alongside household expenditure survey data and energy intensity figures for product categories. The total UK NNM is estimated as 7.56 EJ year−1(3650 W per capita), 44% of which stems from energy embodied in products and services consumed by households. This is comparable with the metabolism of the UK biosphere (approximately 6.95 EJ year−1). Of the final energy embodied in consumption of goods and services, 46% is dependent on domestic policy decisions and 54% is dependent on policy decisions with/in key trading partners. We demonstrate the applicability of this metric by exploring the relationship between NNM and social deprivation in the UK.