bluuebunny/crossref_metadata_2025 huggingface dataset:
An Efficient Quantile-Based Adaptive Sampling RBDO with Shifting Constraint Strategy
Authors: Rahmani Shima , Fadakar Elyas , Ebrahimi Masoud
Published: March 2023

There is an increasing demand for the performance optimization under the reliability constraints in various engineering problems. These problems are commonly known as reliability-based design optimization (RBDO) problems. Among different RBDO frameworks, the decoupled methods are widely accepted for their high efficiency and stability. However, when facing problems with high nonlinearity and nonnormally distributed random variables, they lose their computational performance. In this study, a new efficient decoupled method with two level quantile-based sampling strategy is presented. The strategies introduced for two level sampling followed by information reuse of nearby designs are intended to enhance the sampling from failure region, thus reducing the number of samples to improve the efficiency of sampling-based methods. Compared with the existing methods which decouples RBDO in the design space and thus need to struggle with searching for most probable point (MPP), the proposed method decouples RBDO in the probability space to further make beneficial use of an efficient optimal shifting value search strategy to reach an optimal design in less iterations. By comparing the proposed method with crude MCS and other sampling-based methods through benchmark examples, our proposed method proved to be competitive in dramatically saving the computational cost.
Applications of High-Pressure Die-Casting (HPDC) Magnesium Alloys in Industry
Authors: Fan Sophia , Wang Xu , Gang Wang Gerry , P. Weiler Jonathan
Published: March 2023

High-pressure die-cast (HPDC) magnesium alloys have seen diverse applications in the automotive industry, primarily driven by requirements in internal combustion engine (ICE) vehicles. As the automotive industry is transitioning to an electric vehicle (EV) architecture, there is a great potential for novel applications to improve driving range efficiency. In addition, there is a trend toward larger-sized automotive die castings and an increased interest in aerospace applications due to weight reduction. In this chapter, we reviewed the traditional automotive structural applications in ICE vehicles, as well as current and potential future EV and aerospace applications of HPDC magnesium alloys. The structural applications using AM50, AM60, AZ91 and AE44 magnesium alloys in traditional vehicles can be applied to modern EVs. Additionally, magnesium alloys with varying degrees of higher thermal conductivity, improved castability, superior high temperature properties and flammability need to be developed to replace battery and aerospace in-cabin-related structural materials to meet all safety requirements. Several newly developed magnesium alloys with superior castability are also reviewed for potential automotive and aerospace applications.
Prioritising Integration of Refugees in Municipal Planning at a Local Political Level
Authors: Busengdal Elisabeth
Published: March 2023

The recent increase in refugees in Europe highlights the need to advance ways to implement integration policies, develop practice, and improve integration services and programmes.The primary concern of this article is to examine municipalities that have used municipal planning as a strategic tool to improve integration practices. The article is grounded in qualitative research findings from a case study of two Norwegian municipalities.

The key findings indicate that strengthening the administrative and political foundations for integration and involving more partners in the field of integration, appear to be the most evident motives. Using municipal planning as a strategic tool can be beneficial for municipalities with a lack of intersectoral collaboration, difficulties providing and coordinating services, and problems sustaining the engagement of municipal employees in the work of integration. In the two studied municipalities, planning processes was seen as a way of addressing these issues.
Special Issue Introduction: What Has Changed and What Remains? Institutional Shifts in Nordic Higher Education in the 2000s
Authors: Poutanen Mikko , Tervasmaki Tuomas , Pinheiro Rómulo , Geschwind Lars
Published: March 2023

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Pirtobrutinib (Jaypirca): A Fourth Bruton's Tyrosine Kinase Inhibitor for Mantle Cell Lymphoma
Authors:   Editors from The Medical Letter
Published: March 2023

The Bruton's tyrosine kinase (BTK) inhibitor pirtobrutinib (Jaypirca – Lilly) has received accelerated approval from the FDA for treatment of relapsed or refractory mantle cell lymphoma (MCL) in adults who received ≥2 prior lines of systemic therapy, including a BTK inhibitor. Accelerated approval was based on the response rate. The BTK inhibitors ibrutinib (Imbruvica), acalabrutinib (Calquence), and zanubrutinib (Brukinsa) are also approved for treatment of MCL.
Live Fecal Microbiota (Rebyota) for Prevention of CDI Recurrence
Authors:   Editors from The Medical Letter
Published: March 2023

The FDA has approved Rebyota (Ferring), a rectally-administered, live fecal microbiota suspension, for prevention of additional recurrences of Clostridioides difficile infection (CDI) following antibiotic treatment for a recurrent episode of CDI in adults. Rebyota is the first microbiome-based treatment to be approved for this indication. It is not approved for initial treatment of CDI. Fecal microbiota transplantation (FMT) has been used in patients with multiple CDI recurrences.
A COMPETENT APPROACH TO TEACHING COMPUTER SCIENCE
Authors: Жаркынбаева Б.
Published: March 2023

This article describes the activities of the teacher, work experience aimed at the formation of core competencies in the computer science lesson. When implementing the competence approach, the emphasis is on developing new teacher positions, organizing such a lesson, the main purpose of which is to teach how to learn.
HISTORICAL EVOLUTION OF MUSIC EDUCATION
Authors: Сейдахметов М.
Published: March 2023

This article reflects the thoughts of researchers that the Kyrgyz actively interact with the surrounding ethnic groups, despite regional, social and other differences, preserve the original appearance of the Kyrgyz and make a great contribution to the development of national culture.
Sosialiasi Pembuatan NPWP Menggunakan Aplikasi E-Registration Bagi Pelaku UMKM Di Lembang Randan Batu, Tana Toraja
Authors: Ta’dung Yohanis Lotong , Pongtuluran Althon K.
Published: March 2023

The purpose of this service is to introduce the process of making a quick and easy NPWP in order to increase understanding of UMKM in fulfilling their tax obligations. This community service activity is a community service activity that will be carried out in December 2022. Lembang Randan Batu is an area that continues to develop with several UMKM. This training method begins with the terms and procedures for making an NPWP, the rights and obligations of taxpayers and the benefits of NPWP, procedures for bookkeeping and recording, as well as procedures for calculating and reporting MSME taxes. Preparation for community service is carried out in several stages, namely (1) analyzing the situation and identifying the needs of UMKM, (2) Providing training materials socialized by instructors to performer UMKM and discussing tax issues, (3) program evaluation in implementing activities community service. The results of the activities that have been carried out are that UMKM actors have not registered themselves as taxpayers because they do not know the procedure for making an NPWP and limited information regarding the requirements and how to make an NPWP, and performer UMKM have not carried out bookkeeping and recording of their financial transactions. This training shows the level of understanding of performer UMKM on the importance of understanding taxation. The positive response was seen from the enthusiasm of the training participants participating in community service activities. Most (50%) participants understood taxation, the importance of taxes, making NPWP, and were able to understand PP Number 23 of 2018.
Vozes femininas plurilíngues atravessando a fronteira Venezuela-Brasil
Authors: Silva Brito da Luz Débora
Published: March 2023

O objetivo do presente artigo é oportunizar, ainda que de forma sucinta, a duas mulheres venezuelanas contar suas experiências como imigrantes trabalhadoras na cidade de Boa Vista, capital do estado de Roraima, especialmente, no tocante a aspectos linguísticos, culturais e identitários. As informações foram coletadas por meio de entrevistas gravadas em áudio mediante a assinatura do Termo de Consentimento Livre e Esclarecido. A intenção é de colaborar com a compreensão da realidade sociocultural e linguística vivenciada, sobretudo, por imigrantes da Venezuela em Boa Vista em decorrência do contato de falantes de línguas distintas. Inicialmente, devido ao preconceito sofrido diariamente, as entrevistadas estavam receosas em responder as nossas perguntas, mas logo se sentiram à vontade. Durante as entrevistas, elas alternavam entre o espanhol e o português, revelando grande fluência e competência comunicativa neste último, bem como marcas identitárias relacionadas ao uso de uma ou de ambas as línguas em contato.
O futuro nas aulas de PLA: utilizando o tempo semântico para redefinir a nomenclatura
Authors: Sá Thaís Maíra Machado de , Oliveira Cândido Samuel Fonseca de , Vieira Cláudia Brandão
Published: March 2023

Os tempos verbais fazem parte do aprendizado de todo falante de língua adicional. Neste artigo, fazemos uma reflexão sobre a nomenclatura dos tempos futuro do modo indicativo em livros de PLA (Português Língua Adicional). Cinco livros foram analisados em dois aspectos: (i) como a nomenclatura utilizada para classificar os diferentes tipos de futuro se relacionam com a semântica ou forma dos mesmos; (ii) se os livros abordam questões relacionadas à semântica e ao uso do tempo verbal. Observamos que nenhum dos livros leva em consideração a noção de tempo semântico do verbo. Finalizamos apresentando uma proposta didática a partir do uso que simplifica a nomenclatura gramatical dos tempos verbais nos livros de PLA, deixando-a mais próxima de sua realidade semântica.O futuro nas aulas de PLA: utilizando o tempo semântico para redefinir a nomenclatura
O ERE em língua portuguesa: estratégias pedagógicas com as TDICS em formação inicial de professores
Authors: Pamplona Gustavo Justino , Rodrigues Maiara Coelho , Barros Elizenice de Vasconcelos Peixoto , Karlo-Gomes Geam
Published: March 2023

Com o Ensino Remoto Emergencial – ERE, as tecnologias digitais ganharam ainda mais espaço na formação inicial de professores, as quais possibilitam a criação de novas maneiras de mobilizar o conhecimento. Nesse sentido, o atual estudo busca avaliar o aporte pedagógico de aplicativos digitais no trabalho docente de professores em formação inicial com a produção do gênero textual resenha, levando em consideração a competência 7 e o campo de atuação das Práticas de estudo e pesquisa da Base Nacional Comum Curricular (BRASIL, 2018). As atividades de produção da resenha foram instrumentalizadas por meio da Sequência Didática de Gênero (DOLZ, NOVERRAZ e SCHNEUWLY, 2004). Por meio dessa proposta experimental, avalia-se que os professores em formação inicial conseguiram utilizar de forma adequada as ferramentas digitais para a aprendizagens do gênero no campo social das Práticas de estudo e pesquisa e, consequentemente, adquiriram novas experiências que ampliaram sua formação teórica e prática. Esse choque de realidade provocado pelo ERE também possibilitou lidar com diversas situações escolares e perceber as necessidades de aprendizagem das competências de linguagem da turma.
O ensino de Literaturas na Base Nacional Comum Curricular do Ensino médio: apontamentos críticos
Authors: Mendes Morais Gabriela , Corrêa Martins Silva Machado Rodrigo
Published: March 2023

O ensino de literatura que existe na escola de educação básica brasileira não consegue satisfazer as problemáticas históricas no setor da educação no país, fazendo com que muitos estudantes se sintam frustrados nos processos de formação literária. Levando isso em consideração, este estudo propôs investigar como se dá o ensino de literatura e a formação de leitores na transição do Ensino Fundamental para o Ensino Médio, além de contribuir para o desenvolvimento conceitual dos estudos acerca da formação literária. Para isso, analisamos os documentos oficias da educação, com foco na Base Nacional Comum Curricular (2018), de forma que foi possível alçar conclusões sobre a falta de praticidade do documento enquanto orientador para a formulação dos currículos escolares. Além disso, ao longo do estudo foi debatida a necessidade de propostas que reivindiquem a melhoria na formação docente e ao não silenciamento das particularidades e vivências dos alunos.
Una Revisión Teórica de la Gestión Educativa y el Involucramiento de Padres de Familia en los Procesos Formativos
Authors: Zhapa Amay Fredi Patricio , Vega Mena Carmen Paola , Vega Mena Ladi Patricia
Published: March 2023

El Propósito del presente estudio es realizar una revisión bibliográfica acerca de la gestión educativa y su relación con el involucramiento de padres familia, para determinar su incidencia en el rendimiento académico de los estudiantes de sub nivel inicial a bachillerato. Trabajo que se realizó a través de la búsqueda de información de diversas investigaciones realizadas en este campo de estudio. Mediante un protocolo de enfoque analítico se seleccionó los trabajos de mayor relevancia en relación con el tema analizado. El resultado de mayor preeminencia refiere que de acuerdo con el desarrollo evolutivo y año académico de sus hijos la intervención  disminuye  progresivamente, acentuándose más su participación en los primeros años de estudio de sus representados.
TINJAUAN HUKUM ISLAM TENTANG WANITA PEKERJA DALAM MEMBANTU EKONOMI KELUARGA
Authors: Jumadi Wahyuni
Published: March 2023

Abstrak: Penelitian artikel ini dilatarbelakangi banyaknya perempuan yang ikut berperan serta dalam pemenuhan nafkah keluarga poersoalan dari wanita karir sebetulnya tidak hanya terkaitt aspek normatif dari ajaran Islam semata, namun keberadaannya juga menyentuh dari bentuk aspek psikologis maupun sosiologis keluarga. Maka dari itu, penelitian ini memiliki tujuan, yakni untuk mengetahui tinjauan islam dalam hal wanita yang bekerja untuk membantu ekonomi keluarga, dalam hal ini membantu perekonomian keluarga saat menghadapi persoalan-persoalan ditengah menurunnya ekonomi keluarga dengan tuntutan ekonomi untuk kebutuhan yang semankin meningkat.  Penulisan artikel ini menggunakan metode penelitian kepustakaan, dimana penelitian ini mengumpulkan beberapa literatur untuk menjadikannya referensi dalam penulisan artikel ini. Di dalam Hukum Islam juga tidak dilarang seorang perempuan dalam membantu suaminya saat mencari nafkah, namun mereka harus tetap ingat kepada kodratnya sebagai seorang perempuan atau istri bahwa, sebagai sebagai pendidik dari anak-anaknya dan perempuan dari suami agar terwujudnya suatu keluarga yang damai.
Soñador a sueldo
Authors: Vargas Pasaye Rafael Gerardo
Published: March 2023

Rafael Gerardo Vargas Pasaye es alumno del doctorado en Ciencias Sociales, Complejidad y Multidisciplinariedad de la Universidad Iberoamericana León. Director de la agencia de comunicación Sentido Común Medios y Socio Fundador de la consultora Código 27. Publicó en 2006 su poemario titulado Olvidados de segunda mano, editado por Conaculta. Estos poemas son parte de la obra inédita Soñador a sueldo.
Y Jesús dijo: hagamos un pueblo
Authors: Covarrubias Salles Bernadette
Published: March 2023

Ante los desconciertos, sufrimientos e injusticias, presentes en el mundo actual, este pequeño libro quiere ser una invitación a la esperanza.
Indicios del síndrome de Burnout en la obra "Notas de un joven médico” (1924-1927), de Mikhail Bulgákov
Authors: Braga Vieira Fellipe Eduardo , Chaves Rodrigues Filho Lairtes , Gómez López Wenceslaa
Published: March 2023

Este artículo explora el síndrome de agotamiento profesional en la narrativa del médico-escritor Mikhail Bulgákov, de la obra "Notas de un joven médico (1924-1927)". Cuestionar la existencia de rasgos literarios que expongan el mencionado síndrome. Utilizando el método de análisis de contenido, que obtuvo resultados positivos en la búsqueda de las tres hipótesis utilizadas. Se trata de la comprobación del agotamiento físico, emocional y profesional. En la literatura mundial se busca una comprensión sesgada del estudio del desgaste profesional de los médicos.
Palabras clave: Síndrome de agotamiento profesional, Mikhail Bulgákov, Análisis de contenido.
 
Abstract
This article explores the syndrome of professional burnout in the narrative of the physician-writer Mikhail Bulgákov, from the work "Young Doctor’s Notebook” (1924-1927). To question the existence of literary features exposing the mentioned syndrome. Using the method of content analysis, which obtained positive results in the search for the three hypotheses used. It is about the verification of physical, emotional and professional. A biased understanding of the study of professional burnout in physicians is sought in the world.
Keywords: Burnout syndrome, Mikhail Bulgákov, Content analysis.
Detección precoz del cáncer de cuello uterino y sus determinantes: Un análisis de los resultados de los exámenes en una clínica universitaria de la ciudad de Pedro Juan Caballero, Paraguay
Authors: Chaves Pereira Henya , Soares de Souza Pedro Augusto , Klassen Grzechota Sandra , Dos Santos Guedes Gomes Stephania , Da Silva Arruda Yasmin , Fortaleza de Melo João Italo
Published: March 2023

Este artículo presenta una investigación sobre el diagnóstico precoz del cáncer del cuello uterino (CCU) por medio del examen Papanicolau, abordando sus determinantes y factores en pacientes con características citopatológicas, que influyen para que el examen sea considerado como un instrumento sencillo y disponible a las mujeres de Pedro Juan Caballero, Paraguay. El CCU es una enfermedad causada por el papiloma humano virus (VPH) que afecta principalmente mujeres en edad reproductiva y es la segunda causa de cáncer en mujeres en Paraguay. Los VPH son un grupo de aproximadamente 200 virus, responsables por alrededor del 98% de los casos de CCU, donde cerca de 14 son considerados de alto riesgo. Histopatológicamente, el CCU se presenta por tumores de células escamosas, glandulares, mesenquimales o de células germinales, siendo que los primeros son reconocidos como lesiones precursoras o de estadio inicial. Este trabajo discute el cáncer de cuello uterino, su prevalencia y diagnóstico, a partir de un marco teórico basado en artículos científicos internacionales. La recolección de datos documentales se realizó a través de registros médicos de atención obtenidos en la Clínica Central de la Universidad Central del Paraguay. Este estudio retrospectivo es de corte transversal y analítico con un abordaje demográfico.
Palabras Clave: Cáncer, Diagnóstico Precoz, Papanicolau
 
Abstract
This article presents research on the early diagnosis of cervical cancer (CC) through the Pap test, addressing its determinants and factors in patients with cytopathological characteristics, which influence the examination to be considered as a simple instrument available to women in Pedro Juan Caballero, Paraguay. CC is a disease caused by the human papillomavirus (HPV) that mainly affects women of reproductive age and is the second cause of cancer in women in Paraguay. HPVs are a group of approximately 200 viruses, responsible for about 98% of CC cases, where about 14 are considered high risk. Histopathologically or logically, CC is presented by tumors of squamous, glandular, mesenchymal or germ cell tumors, the former being recognized as precursor lesions or from this to initial one. This paper discusses cervical cancer, its prevalence and diagnosis, from a theoretical framework based on international scientific articles. Documentary data were collected through medical records of care obtained at the Central Clinic  of the Central University of Paraguay. This retrospective study is cross-sectional and analytical with a demographic approach.
Keywords: Cancer, Early Diagnosis, Pap Smear
Insuficiencia cardíaca en paciente chagásico: Reporte de caso
Authors: Oliveira Mota Bruno , Souza Bianca , Marciel Leidaiana , Queiroz Vitoria , Dos Santos Wesley José
Published: March 2023

La enfermedad de Chagas es la causante de 12.000 muertes anuales como consecuencia de una miocardiopatía chagasica crónica que se presenta en un 20 a 30% de los infectados, con síntomas a partir de los 60 años del paciente, donde llega a presentar insuficiencia cardíaca. Es la tercera enfermedad parasitaria más prevalente, causada por Trypanosoma cruzi (T. cruzi), predominante en América Latina. El diagnóstico se basa en la epidemiología, imagen, hallazgos clínicos, cambios electrocardiográficos y pruebas de imagen asociadas a la serología. El objetivo del presente trabajo ha sido realizar un reporte de caso de un paciente que presentó insuficiencia cardíaca con enfermedad de Chagas. Los resultados demuestran la importancia de un diagnóstico oportuno de la enfermedad para no llegar a la etapa sintomática.
Palabras clave: Insuficiencia cardíaca, heridas, muerte.
 
Abstract
Chagas disease is the cause of 12,000 deaths annually because of chronic chagasic cardiomyopathy (CCC) that occurs in 20 to 30% of those infected, with symptoms after the age of 60, where it presents heart failure. It is the third most prevalent parasitic disease, caused by Trypanosoma cruzi (T. cruzi), which is predominant in Latin America. Diagnosis is based on epidemiology, clinical imaging findings, electrocardiographic changes, and imaging tests associated with serology. The objective of this paper was to present a case report of a patients who presented heart failure with Chagas disease. The results demonstrate the importance of a timely diagnosis of the disease in order not to reach the symptomatic stage.
Keywords: Heart failure, injuries, death.
Tabaquismo y el estudiante de Medicina: investigación sobre perfil y percepción de riesgo
Authors: Pereira da Silva Schiave Ana Lucia , Sande Rolon Valeria Yasmin
Published: March 2023

El tabaquismo es considerado la principal causa de muerte evitable en el mundo. Entre los varios grupos de personas que hacen uso del tabaco se encuentran los jóvenes, pero ¿Cómo se puede determinar el tipo de tabaco consumido por los mismos? Este estudio transversal descriptivo tiene por objeto analizar el perfil del tabaquismo en los alumnos de la Universidad Central del Paraguay, Filial Pedro Juan Caballero. Se constata que la prevalencia en el consumo del tabaco se da en hombres jóvenes por medio del cigarrillo industrializado y electrónico, asociado a la búsqueda de disminuir la ansiedad. Se recomienda otros estudios acerca de la temática y el desarrollo de medidas educativas acerca de los daños causados por el uso del tabaco.
Palabras clave: Tabaquismo, ansiedad, estudiantes de medicina.​
 
AbstractTradução para Inglês. 
Smoking is considered the leading cause of preventable death in the world. Among the various groups of people who use tobacco are young people, but how can you determine the type of tobacco consumed by them? This descriptive cross-sectional study aims to analyze the profile of smoking in students of the Central University of Paraguay, Pedro Juan Caballero Branch. It is found that the prevalence of tobacco consumption occurs in young men through industrialized and electronic cigarettes, associated with the search to reduce anxiety. Further studies on the subject and the development of educational measures on the harms caused by tobacco use are recommended.
Keywords: Smoking, anxiety, medical student
O delírio paranoico
Authors: Rabêlo Fabiano Chagas , Santos Gerlane Nanncy Alencar dos
Published: March 2023

Investiga-se a construção do delírio na paranoia a partir do comentário de trechos do livro de Dostoiévski "O duplo". Nele, a temática do Doppelgänger, que é central para o entendimento do sistema delirante do protagonista, surge como uma tentativa de tratamento de conteúdos foracluídos (verworfen) que retornam de forma disruptiva. Dessa forma, o delírio se desenvolve como anteparo à uma vivência de aniquilação subjetiva, que irrompe em situações nas quais as dificuldades do protagonista em se inserir nos laços sociais se agudiza. O artigo coteja trechos do livro de Dostoiévski com a análise freudiana da autobiografia de Schreber, apoiando-se para tanto nas considerações de Lacan, Maleval, Rabinovicht, Soler e Quinet sobre a sintaxe do delírio. Valorizam-se os conceitos de compulsão à projeção, secretário do alienado, discurso fechado e interpretação autoreferente para o entendimento das falas, motivações e ações do personagem principal.
Aspectos Psicométricos da Escala de Ansiedade à Matemática
Authors: Brelaz-da-Silva Ivonilce , Maximino Caio
Published: March 2023

O presente estudo analisou a confiabilidade e a estrutura fatorial da Escala de Ansiedade à Matemática (EAM), bem como parâmetros de item avaliados por análise de Rasch. A EAM foi aplicada a estudantes do Ensino Médio de uma escola pública do interior do Pará, através de formulário online. A escala apresentou boa confiabilidade (α = 0,947), e estrutura de dois fatores, identificados preliminarmente como Ansiedade Numérica e Ansiedade à Avaliação Matemática. Os itens do fator Ansiedade à Avaliação Matemática apresentaram maior média e menor dificuldade do que os itens do fator Ansiedade Numérica. Esses resultados sugerem que a EAM é confiável, robusta, e capaz de capturar a estrutura latente do construto Ansiedade à Matemática.
Consultoria colaborativa na Educação Infantil
Authors: Lima Adriana Sanches Sisto , Pereira Veronica Aparecida
Published: March 2023

Nesse estudo descreve-se uma intervenção realizada junto à educação infantil na fase inicial da pandemia por COVID-19. Norteiam essa prática os princípios da Consultoria Colaborativa. Participaram do estudo 11 famílias, com filhos de até três anos, frequentadoras de um Centro de Convivência Infantil, em Dourados-MS. A Consultoria Colaborativa foi realizada à distância, por videochamada, em três etapas:  1) entrevistas com as mães; 2) orientação e planejamento; e 3) devolutiva e avaliação. As atividades foram norteadas a partir do protocolo do Inventário Portage Operacionalizado (IPO), contextualizadas no cotidiano das famílias, discutidas e planejadas individualmente. A comparação dos resultados antes e depois da intervenção indicou aumento das médias em todas as subáreas do protocolo de autocuidados, com diferenças significativas para vestuário (p=0,017), higiene (p=0,008) e índices totais (p=0,005). A Consultoria Colaborativa possibilitou a realização de atividades integradas à rotina familiar, podendo ser viável após a pandemia.
Considerações sobre o método fenomenológico de Amadeo Giorgi
Authors: Barbosa Caroline Garpelli
Published: March 2023

O presente artigo, de natureza teórica, tem como objetivo apresentar e discutir uma das propostas metodológicas mais utilizadas e difundidas no interior da tradição fenomenológica no campo das pesquisas qualitativas em psicologia, que é o método desenvolvido por Amadeo Giorgi e fundamentado na fenomenologia de Edmund Husserl. O intuito será demarcar as possibilidades de realização desse método, bem como discutir alguns de seus alcances e limites. Ao final, o texto traz algumas indicações de que a perspectiva hermenêutica parece oferecer uma possibilidade mais ampla e historicamente situada acerca do fenômeno a ser estudado quando comparada ao método mais tradicional de Giorgi, sendo talvez um complemento a esse.
Ecdótica epistolar, indexación y redes personales
Authors: Juárez López Andrés
Published: March 2023

Este artículo aborda la indexación de textos epistolares y su relación con la elaboración de índices analíticos. Para ello, examinamos algunas herramientas de las humanidades digitales y nos detenemos en el papel de la interpretación de los datos obtenidos. A través de la aplicación de un modelo propuesto para la correspondencia intercambiada entre Elisabeth Mulder y Consuelo Berges se procede al análisis cuantitativo y cualitativo del universo contenido en estas cartas. Tal análisis nos muestra la configuración histórica del contexto de dos autoras de la Edad de Plata en su correspondencia de posguerra, la incidencia del componente de género en la misma y la existencia simultánea de redes de cooperación y de confrontación. Finalmente, presentamos algunas propuestas para trasladar al diseño del índice analítico parte de los resultados del análisis de los datos indexados.
Droit des pauvres, pauvres droits : la Chambre de la jeunesse, au carrefour des inégalités et de la nouvelle gestion publique
Authors: Bernheim Emmanuelle
Published: March 2023

Sous l’impulsion de la nouvelle gestion publique, la judiciarisation est en pleine augmentation à la Chambre de la jeunesse de la Cour du Québec. Cette judiciarisation est marquée par d’importantes inégalités, à l’intersection du genre, de la classe et de la race. L’accès aux droits et à la justice des parents et les conditions de la pratique en droit de la jeunesse sont pourtant peu documentés à ce jour.

À partir d’un terrain de recherche qualitatif, composé d’entrevues et d’observations, l’article qui suit présente, dans un premier temps, la concordance des expériences des avocates de la défense et des parents à la Chambre de la jeunesse ; dans un second temps, l’auteure discute de la judiciarisation comme amplificateur des inégalités sociales. La conclusion traite de la consistance de ces constats avec ceux qui viennent de recherches menées dans d’autres champs du droit social.
Do Children’s “Best Interests” Matter When Tracing Their Filiation in Quebec Civil Law ?
Authors: Campbell Angela
Published: March 2023

This essay offers a commentary on the intersection between the best interests principle and the law of filiation in Quebec. It highlights the tension between best interests and the positive law of filiation, highlighting the implications for those most vulnerable in family law disputes who have been central to Professor Goubau’s scholarship. The analysis here is premised on a review of four relatively recent decisions handed down by Quebec courts, each distinct in its context. The first considers circumstances of assisted procreation or “parental projects” that result in more than two prospective parents ; the second addresses intercultural adoption contexts ; the third examines determinations of filiation where a child’s birth ensues from a surrogacy agreement ; and the fourth explores how the law deals with stepparent-stepchild relationships. In each context, a judgment is featured to explore how the law intersects with the best interests principle. While none of the judgments are intended to be representative of the state of the law in a given area, each offers an example to illustrate how courts negotiate tensions between the positive law and the best interests principle. While judges will have varying degrees of discretion in different contexts to consider this principle, they acknowledge the tension and seek to reconcile it in a manner that at once foregrounds children’s interests while also correctly applying and interpreting relevant legal authorities.
Understanding the New Analogue Photography: Meanings, Methodologies and Aesthetics
Authors: Margadona Laís Akemi
Published: March 2023

This paper examines the resistance and revival of outmoded photographic technologies, in a new format we call “new analogue photography”. This type of image resignifies old analogue practices as stated by Ansel Adams (2019a, 2019b, 2018) in three key areas: 1. meaning, 2. methodology, and 3. aesthetics. It is the grain image adapted to the connected media ecosystem in post-photographic times. The contribution of millennials and gen Z to the growth of this type of photography is presented and discussed. At the conclusion, the decalogue of the new analogue photography is stated, summing up its practice and significance across ten topics.
Ablation of palladin in adult heart causes dilated cardiomyopathy associated with intercalated disc abnormalities
Authors: Mastrototaro Giuseppina , Carullo Pierluigi , Zhang Jianlin , Scellini Beatrice , Piroddi Nicoletta , Nemska Simona , Filomena Maria Carmela , Serio Simone , Otey Carol A , Tesi Chiara , Emrich Fabian , Linke Wolfgang A , Poggesi Corrado , Boncompagni Simona , Bang Marie-Louise
Published: March 2023

Palladin (PALLD) belongs to the PALLD/myopalladin (MYPN)/myotilin family of actin-associated immunoglobulin-containing proteins in the sarcomeric Z-line. PALLD is ubiquitously expressed in several isoforms, and its longest 200 kDa isoform, predominantly expressed in striated muscle, shows high structural homology to MYPN. MYPN gene mutations are associated with human cardiomyopathies, whereas the role of PALLD in the heart has remained unknown, partly due to embryonic lethality of PALLD knockout mice. In a yeast two-hybrid screening, CARP/Ankrd1 and FHOD1 were identified as novel interaction partners of PALLD’s N-terminal region. To study the role of PALLD in the heart, we generated conditional (cPKO) and inducible (cPKOi) cardiomyocyte-specific PALLD knockout mice. While cPKO mice exhibited no pathological phenotype, ablation of PALLD in adult cPKOi mice caused progressive cardiac dilation and systolic dysfunction, associated with reduced cardiomyocyte contractility, intercalated disc abnormalities, and fibrosis, demonstrating that PALLD is essential for normal cardiac function. Double cPKO and MYPN knockout (MKO) mice exhibited a similar phenotype as MKO mice, suggesting that MYPN does not compensate for the loss of PALLD in cPKO mice. Altered transcript levels of MYPN and PALLD isoforms were found in myocardial tissue from human dilated and ischemic cardiomyopathy patients, whereas their protein expression levels were unaltered.
Structures of ferroportin in complex with its specific inhibitor vamifeport
Authors: Lehmann Elena Farah , Liziczai Márton , Drożdżyk Katarzyna , Altermatt Patrick , Langini Cassiano , Manolova Vania , Sundstrom Hanna , Dürrenberger Franz , Dutzler Raimund , Manatschal Cristina
Published: March 2023

A central regulatory mechanism of iron homeostasis in humans involves ferroportin (FPN), the sole cellular iron exporter, and the peptide hormone hepcidin, which inhibits Fe2+ transport and induces internalization and degradation of FPN. Dysregulation of the FPN/hepcidin axis leads to diverse pathological conditions, and consequently, pharmacological compounds that inhibit FPN-mediated iron transport are of high clinical interest. Here, we describe the cryo-electron microscopy structures of human FPN in complex with synthetic nanobodies and vamifeport (VIT-2763), the first clinical-stage oral FPN inhibitor. Vamifeport competes with hepcidin for FPN binding and is currently in clinical development for β-thalassemia and sickle cell disease. The structures display two distinct conformations of FPN, representing outward-facing and occluded states of the transporter. The vamifeport site is located in the center of the protein, where the overlap with hepcidin interactions underlies the competitive relationship between the two molecules. The introduction of point mutations in the binding pocket of vamifeport reduces its affinity to FPN, emphasizing the relevance of the structural data. Together, our study reveals conformational rearrangements of FPN that are of potential relevance for transport, and it provides initial insight into the pharmacological targeting of this unique iron efflux transporter.
Listen to the shopkeeper
Authors: Maciel-de-Freitas Rafael
Published: March 2023

His mosquito control project heading for failure, a field entomologist recalls how a chance encounter led to a Eureka moment.
Level of attention mediates the association between connectedness to nature and aesthetic evaluations of photographs of nature
Authors: Harrison Neil
Published: March 2023

Aesthetic experiences of nature are associated with beneficial psychological and behavioural outcomes. We investigated in a laboratory study whether an individual’s level of connectedness to nature is associated with their aesthetic sensitivity to images of natural scenes, and whether the amount of attention allocated to the images mediated this association. Participants (N = 82) viewed 14 photographs depicting natural scenes and evaluated them on three aesthetic dimensions and completed the Connectedness to Nature (CN) and Openness to Experience (OtE) scales. CN positively predicted pleasure, beauty and aesthetic emotion, independently of OtE. The amount of attention participants paid to the images mediated the relationship between connectedness to nature and aesthetic pleasure, and connectedness to nature and beauty ratings. These findings extend our understanding by showing that attention is an important mechanism through which nature connectedness influences aesthetic responses of pleasantness and beauty in response to natural scenes. The findings have real-world implications as appreciation of the aesthetic qualities of nature is associated with a number of beneficial psychological outcomes.
Comparative Evaluation of Colour Difference using Different Digital Photography Equipment to Standardise Colour Assessment in Dental Photography
Authors: Patel Jaimini Jigar , Shah Nimisha Chinmay , Shah Ruchi Rani , Kothari Meghna , Porwal, Priya , Batra Renu
Published: March 2023

Introduction: Photography has always been thought to be an important part of dentistry. Since the introduction of digital technology; imaging has become simpler and more accessible. Colour matching is critical for the success of restorative and prosthetic dental treatments, also communication with the dental laboratory is still subjective, and further research is needed on this aspect. Aim: To compare the colour difference of digital photography equipment to standardise colour assessment in dental photography. Materials and Methods: A single blind clinical study was conducted after Clinical Trial Registry of India (CTRI) registration and informed consent, and a total of 22 participants were enrolled in accordance with the selection criteria. A spectrophotometer was used to determine the CIELAB ( Colour space defined by International Commission on Illumination) values of the right central incisor for each participant. They were then photographed with five different photography equipment along with a grey reference card. Group A: Canon 1300D Digital Single Lens Reflex (DSLR) with 100 mm lens and pop-up flash (N=22). Group B: Canon 1300D DSLR+100 mm lens+70 GSM white tissue paper (N=22). Group C: Canon 1300D DSLR+ 100 mm lens with ring flash (N=22). Group D: Canon 1300D DSLR+100 mm lens+ring flash+diffuser (N=22). Group E: Iphone 11 (N=22). CIELAB values were obtained for all the groups using adobe Photoshop software after white balancing. Delta E was calculated by comparing CIELAB values of each group with the spectrophotometer values. The data was tabulated and analysed with one way ANOVA and Post-hoc test using IBM SPSS 20 software with p<0.05 considered statistically significant. Results: Mean value of Delta E was least in group D (DSLR+ ring flash with diffuser) (5.033) followed by group B (DSLR+ pop up flash with white tissue paper) (6.57), group A (DSLR+pop-up flash) (10.70), group E (Iphone11) (10.74) and highest in group C (DSLR+ ring flash) (11.32). Conclusion: Group D (DSLR+ ring flash with diffuser) was determined to be closest to the standard spectrophotometric values for colour assessment in dental photography
Correlation of Pupil Cycle Time and Postural Hypotension as a Marker for Diabetic Neuropathy
Authors: Kotian Vasanthi B , Hegde Puneet
Published: March 2023

Introduction: Diabetic Neuropathy (DN) can involve autonomic nervous system like cardiovascular system and pupillary reflex. Cardiovascular DN can be measured by estimating the change in Blood Pressure (BP) based on position. Ocular DN can be evaluated by using Pupil Cycle Time (PCT), which is an early diagnostic tool to estimate ocular DN. It is a simple way to measure autonomic reflex activity and is a specific test to study parasympathetic function. Aim: To assess the correlation of effects of postural hypotension and PCT on persistent diabetes. Materials and Methods: The prospective cross-sectional study was conducted in Ophthalmology Out Patient Department (OPD) at KS Hegde Medical Academy, Mangalore, Karnataka, India, from January 1st 2019 to December 31st 2019. The study included 60 male patients between the age group of 40-60 years which were divided into two groups of 30 diabetics (Random Blood Sugar (RBS) >200 mg/dL, Fasting Blood Sugar (FBS) >126 mg/dL and Glycated Haemoglobin (HbA1c) >6.5%) and 30 non diabetics. The blood pressure of all the patients were recorded using a sphygmomanometer in sitting and standing positions. PCT was measured in both eyes using Haggstreittype of slit lamp after the subject was seated in a dimly lit room after dark adaptation for 15 minutes. Results: The mean age of patients in the diabetic group was 54±3.2 years and the non diabetic group was 52±2.7 years. The mean HbA1c of diabetics was 6.9±0.8%. The mean BP among diabetics in standing position was 133.86±29.34 mmHg systolic and 87.4±16.72 mmHg diastolic whereas in sitting position, it was 141.66±28.17 mmHg systolic and 85.26±13.39 mmHg diastolic. The mean BP among non diabetics in standing position was 129.46±24.84 mmHg systolic and 83.46±13.52 mmHg diastolic whereas in sitting position, it was 132.06±26.48 mmHg systolic and 81.26±11.45 mmHg diastolic. The mean PCT-I and PCT-II in diabetics was 1000.52±187.73 and 1006.09±199.45, respectively. The systolic and diastolic BP, both during sitting and standing postures, in diabetic patients were high. The mean PCT-I and PCT-II in non diabetics was 853.23±181.54 and 880.17±192.72, respectively. The PCT-I and PCT-II were found to be significantly high in diabetic patients as compared to controls. The PCT-I and PCT-II negatively correlated with both diastolic and systolic blood pressure in sitting and standing postures. Conclusion: Prolongation of PCT in diabetics correlates significantly with evidence of autonomic neuropathy obtained from testing of postural BP variations. Patients whose cardiovascular reflexes are very abnormal tend to have pupils which cycle slowly.
Effectiveness of Rythu Bharosa Kendras (RBKs) Services as Perceived by Farmers in the East Godavari District of Andhra Pradesh, India
Authors: Saifuddin Md. , Devy M. Rama , Rao M. S. , Suseela K.
Published: March 2023

Rythu Bharosa Kendram is One Stop Shop for supplying Government Certified Agri Inputs (Seeds, Fertilizers & Pesticides), Animal Husbandry & Fisheries Inputs to the farmers and has an attached workshop / Knowledge Center for giving scientific Agri Advisories to the farmers. It is integrated with a Call. The study investigated the effectiveness of services of RBK perceived by farmers in the East Godavari district of Andhra Pradesh during 2021-2022. A total sample of 120 farmers was randomly selected from twelve villages viz. Kadiyam, Vemagiri, Muramanda, Kalavacherla, Rajanagram, Velugubanda, Geddanapalli, Bhupalapatnam, S. thimmapuram, Bhatnavalli, Rollapalem and Nadipudi of East Godavari district of Andhra Pradesh. The data were collected with structured interview schedule. The perceived effectiveness of the services of RBKs was studied. It was observed that half (50.83%) of the farmers perceived that services rendered by RBKs were moderately effective followed by highly effective (34.17%) and less effective (15.00%) categories. It can be recommended to the government and policy makers for improvement, restructuring, reforming and modifying the services from RBKs to enhance its effectiveness further.
Synthesis, Characterization and Electrochemical Studies on the Corrosion Inhibition Properties of Schiff Bases for Mild Steel in 1 M HCl Solution
Authors: Ozoemena Chimezie P. , Boekom Ekerete Jackson , Akpan Inemesit, I.
Published: March 2023

Schiff bases (SBL1 and SBL2), non-toxic compounds were synthesized, characterized and  investigated as alternative anticorrosive additives for inhibition of mild steel corrosion in I M HCl acid medium. Corrosion of the steel was monitored by Potentiodynamic Polarization (PDP), Linear Polarization Resistance (LPR), Electrochemical Impedance Spectroscopy (EIS) and Weight Loss (WL) techniques. The novel Schiff base ligands obtained were characterized by Ultraviolet-visible and Fourier-Transform Infrared Spectroscopy. The elemental analysis data for the Schiff base ligands were used to confirm the formula of SBL1 as C17H20N2O2 and SBL2 as C24H21N5O2. Fourier-Transform Infrared spectroscopy suggest that the formation of a complex film on the mild steel surface was due to the adsorption of SBL1 and SBL2. The adsorption process was spontaneous and consistent with the mechanism of physical adsorption as best approximated by the Langmuir adsorption isotherm. Maximum inhibition efficiency was obtained at maximum concentration of 100 ppm for both SBL1 and SBL2 with SBL2 possessing the higher inhibition efficiency (86.21%) more than SBL1 (76.92%). Effectiveness of SBL1 and SBL2 reduced with increase in time and progressed with increase in concentration of SBL1 and SBL2. PDP measurements showed that SBL1 and SBL2 acted as a mixed type inhibitor. EIS measurement reveals that the corrosion process was controlled by charge transfer process. Values of the inhibition efficacy obtained from the different techniques were comparable. SEM micrographs of mild steel surface indicated good surface protection of SBL1 and SBL2.
Effect of Irrigation Scheduling and Foliar Organic Nutrition on Growth and Yield of Summer Groundnut (Arachis hypogaea L.)
Authors: Karthik Elukur , Singh Rajesh , Thakur Indu , Pradhan Akankhya
Published: March 2023

A field experiment was conducted during summer season of 2022 at Crop Research Farm (CRF). Department of Agronomy, SHUATS, Prayagraj (UP) on soil with sandy loam in texture with Organic carbon 0.48%, Available Nitrogen 278.93 Kg/ha, Available Phosphorus 19.03 Kg/ha, Available Potassium 238.1 Kg/ha, Soil Ph 7.4, EC 0.47 ds/m to investigate the effect ofrrigation scheduling and foliar organic nutrition on growth and yield of Zaid Groundnut. The treatments consist of three irrigation schedulings viz., I1: 3 irrigations (25,45,70 DAS), I2: 2 irrigations (25,45 DAS), I3: 2 irrigations (25,70 DAS) and three foliar organic nutrition F1 – Panchagavya at 3%, F2 – Jeevamrutha at 3%, F3 – Panchamrutha at 3% whose effect is observed on Groundnut (var. Kadiri-6). The experiment was laid out in randomized block design with ten treatments replicated thrice. The treatment with application of 3 irrigations (25,45,70 DAS) + panchagavya-3% recorded significantly higher plant height (60.07cm) and plant dry weight (39.62 g), number of pods per plant (20.33), number of kernels per pod (2.47), seed index (39.84  g), pod yield (2.85 t/ha) and haulm yield (4.4 t/ha) compared to other treatment combinations. It is concluded that 3 irrigations (25,45,70 DAS) and panchagavya-3% accomplished better growth parameters, yield attributes and higher pod yield in groundnut crop.