bluuebunny/crossref_metadata_2025 huggingface dataset:
Öğretmen Adaylarının Müzelerde Eğitim Uygulamalarına Yönelik Görüşleri
Authors: ŞANDA Emre , DEMİREL İrfan Nihan
Published: January 2024

Araştırmada, lisans programlarının farklı bölümlerinde öğrenim gören öğretmen adaylarının müzelerde eğitim uygulamalarına dair görüşlerinin farklı değişkenler açısından tespit edilmesi amaçlanmıştır. Araştırmada genel tarama modellerinden ilişkisel tarama modeli kullanılmıştır. Araştırmanın çalışma grubunu, bir devlet üniversitesinin farklı öğretmenlik programlarının 3 ve 4. sınıflarında öğrenim gören toplam 806 (3.sınıf= 371; 4.sınıf= 435) öğretmen adayı oluşturmaktadır. Araştırmada öğretmen adaylarının müzelerde eğitim uygulamalarına yönelik görüşlerini belirlemek amacıyla “Müzelerde Eğitim Uygulamalarının Değerlendirilmesi Ölçeği” araştırmacılar tarafından geliştirilerek uygulanmıştır. İkili değişkenlerin karşılaştırılması amacıyla yapılan veri analizinde verilerin normal dağılım göstermesi nedeniyle t testi kullanılmıştır. İkiden fazla değişkenler için grup varyans homojenliği incelenmiştir. Öğretmen adaylarının öğrenim gördükleri programlara göre grup varyanslarının homojenliği Levene testi ile belirlenmiştir. Araştırma kapsamında, öğretmen adaylarının müzelerde eğitim uygulamalarını, müzelerin önemi ve müzelerde yapılacak öğrenme-öğretme süreci etkinlikleri açısından önemli buldukları ancak 4. sınıf öğretmen adaylarının 3. sınıf öğretmen adaylarına göre müzeleri bu süreçler açısından daha olumlu değerlendirdikleri tespit edilmiştir. Araştırmada müze ile ilgili bir ders alan adayların; müze ile ilgili ders almayan adaylara göre müzeleri daha önemli buldukları, müzelerde yapılacak eğitim uygulamaları aracılığıyla öğrenme-öğretme sürecinin daha etkili hale geleceğini ve müzelerde eğitim uygulamalarına yönelik öğretmenlerin daha etkin bir şekilde rol alması gerektiğini düşündükleri sonuçlarına ulaşılmıştır. Müzelerde yaptırılabilecek eğitim uygulamalarına yönelik olarak dersin planlanması, uygulama boyutuna yönelik etkinliklerin tasarlanması ve MEB öğretim müfredatlarında tüm disiplin alanlar için belirlenen kazanımların müze eğitimi ile nasıl ilişkilendirilebileceği noktasında sadece öğretmen adayları değil, öğretmenlerin de bilgilendirilerek bu konuda gerekli hizmet içi eğitimlerin yapılması önerilmektedir.
Identification of patients at risk of cardiovascular disease in greater Manchester in the VICTORION-Spirit study
Authors: Gibson J. Martin , McCrae John , Williams Claire , Wilson Paul M. , Bower Peter , Dixon Samantha
Published: January 2024

Background: Inclisiran is a cholesterol-lowering small interfering RNA treatment licensed in the UK for lowering low-density lipoprotein cholesterol (LDL-C). VICTORION-Spirit (NCT04807400) is an implementation science study designed to provide evidence for inclisiran implementation within the National Health Service. The aim was to describe the process of patient identification employed in VICTORION-Spirit.
Methods: A Phase IIIb, multicentre, randomised controlled study, VICTORION-Spirit is evaluating inclisiran implementation in participants with atherosclerotic cardiovascular disease (ASCVD) or ASCVD-risk equivalents and elevated LDL-C. Feasibility Assessment and Recruitment System for Improving Trial Efficiency (FARSITE) software utilising natural language search functions identified patients who may benefit from inclisiran. FARSITE searches were performed within Salford, Manchester, Trafford and Bury Clinical Commissioning Groups to identify individuals with elevated LDL-C or total cholesterol and pre-existing cardiovascular disease (CVD) or at risk of ASCVD.
Results: FARSITE used ‘total cholesterol >4 mmol/l’ terminology rather than ‘LDL-C’; the former yielded >3 times the number of eligible patients. The search for individuals with pre-existing CVD identified 24,196 people in a population of 560,969 (4.3%); including ‘total cholesterol >4 mmol/l’ identified 10,431 individuals with pre-existing CVD and elevated total cholesterol. Searches for individuals at risk of ASCVD identified 65,457 people, narrowing to 26,580 at risk of ASCVD plus elevated total cholesterol. The most discriminatory SNOMED concept codes and their prevalence within the dataset can inform national approaches to develop similar searches.
Conclusions: FARSITE searches employed in VICTORION-Spirit identified a population at risk of ASCVD in Greater Manchester, England, who may benefit from a cholesterol-lowering medication such as inclisiran.
Community perceptions and willingness to participate in COVID-19 vaccine trials: a qualitative study in Northern Ghana
Authors: Chatio Samuel Tamti , Ansah Nana Akosua , Nonterah Engelbert A. , Bangre Oscar , Awuni Denis , Kuwolamo Irene , Asoala Victor , Ansah Patrick
Published: January 2024

Background: Several COVID-19 vaccines were developed and are being tested to find effective vaccine to control the COVID-19 pandemic. The Navrongo health research centre was engaged to conduct trials on the safety and efficacy of some of the COVID-19 vaccines to inform policy in Ghana. This study explored perceptions and willingness to participate in the COVID-19 vaccine trials that were conducted in the Kassena-Nankana districts of Northen Ghana.
Methods: This study used qualitative research approach where 10 focus group discussions and 30 in-depth interviews were conducted with participants. The data were coded into themes using QSR NVivo 12 software before thematic analysis.
Results: The majority of participants perceived that the COVID-19 vaccine trial was a good initiative, which had helped people to get access to the vaccines to boost their immunity against the virus. However, some participants felt that it was not appropriate for NHRC to conduct the trials because of the perceived risks associated with the vaccines. Most participants said they were ready to participate in the trials if they were invited with many of them mentioning good health and compensation as the main factors that could influence their decision. Nonetheless, a good number of them maintained that they were not ready to participate because of perceived risks resulting from receiving the COVID-19 vaccines.
Conclusion: Our recommendation is that effective community engagement strategies by researchers such as collaborating with key community leaders, to actively get involved during community education prior to conducting clinical trials, could improve understanding and participation.
Comparative study of two thoracic segmental spinal anaesthesia techniques for laparoscopic cholecystectomy: low-dose hypobaric ropivacaine and isobaric ropivacaine at T10-11 intervertebral space vs. standard technique using isobaric levo bupivacaine at T8-T10 intervertebral space
Authors: Nagar Sachin , Paliwal Naresh , Lohia Robin , Saluja Vivek , Dutt Narender
Published: January 2024

Background: Many prior studies have utilized thoracic or lumbar spinal anesthesia with isobaric/hyperbaric bupivacaine or Ropivacaine and opioids for laparoscopic cholecystectomy and have reported variable results. our study is centered around addressing the occurrence of intraoperative right shoulder pain and its potential impact on the need for conversion to general anesthesia.
Methods: This is a prospective comparative case series study in which 70 patients scheduled for elective laparoscopic cholecystectomy were. Patients in Group R received 1 ml (1 mg) of Hypobaric Ropivacaine 0.1% at T10-11 followed by 25 mcg fentanyl, and 5 mg Isobaric Ropivacaine 0.5% whereas patients in Group B received 1.5 ml (7.5 mg) Isobaric levo Bupivacaine 0.5% and 25 mcg fentanyl at T8-T10. Patients in both the groups were compared for incidence of shoulder tip pain and Hemodynamic stability.
Results: Both techniques achieved satisfactory anaesthesia quality, with similar results in surgical anaesthesia onset. Average surgical duration was 45-75 minutes with average of 60 mins with longer durations in two cases common to both the groups. In group R there was there was no bradycardia or hypotension recorded more than 10% of preinduction vitals. Whereas in group B 2 patients had bradycardia and hypotension more than 10% of preinduction vitals.
Conclusions: The T10-11 technique using low-dose (6 mg) hypobaric ropivacaine and isobaric Ropivacaine appears to be superior in terms of shoulder tip pain, and hemodynamic stability compared to the T8-T10 technique using isobaric levo-Bupivacaine alone in higher dose.
Comparison of rapid dengue NS1, qualitative ELISA, and quantitative ELISA result
Authors: Nilekeri Manali , Taklikar Shripad
Published: January 2024

Background: Non-structural glycoprotein-1 (NS1) is a useful biomarker for early diagnosis of dengue fever. NS-1 antigen ELISA can be used for the early diagnosis of dengue fever in the acute stage. Quantitative methods are better for epidemic settings due to high false negative rates in qualitative ELISA.
Methods: The study was initiated after approval from the institutional ethics council (IEC/DISS/17118). Study examined 280 patients with dengue symptoms who presented to the hospital's OPDs and IPDs. Patients were tested using qualitative ELISA, and those with Leptospira antibody, malaria, or Chikungunya IgM antibody were excluded. Age, gender, symptoms, comorbidities, total leucocyte count, platelet count, and risk category were all patient-related parameters. Patient-related parameters were recorded, and data was collected using Microsoft excel and analysed statistically.
Results: Most patients aged 2-40 with male predominance had fever, chills, and body aches, 243 (86.8%) tested positive for ELISA NS1. Quantitative ELISA test showed a statistically significant correlation with rapid antigen NS1 result (p=0.015). Its AUC was 0.883 (p=0.0001), and its cut-off was (>109.1) with 96.9% sensitivity and 13.64% specificity. The AUC of quantitative ELISA NS1 against qualitative ELISA NS1 was 0.853 which was statistically significant (p<0.0001). At the cut-off >74.34, the test's sensitivity was 92.59% and specificity was 75.68%.
Conclusions: Qualitative ELISA NS1 test is better than rapid antigen test for screening due to its higher specificity and similar sensitivity.
A rare case report of accessory thyroid in the superior mediastinum in the form of multinodular goiter
Authors: Kiran Amith , Shetty Swathi U. , B. S. Vishnu Keerthi , Patil Sharangoud
Published: January 2024

Retrosternal expansion of a goiter is one of the most common types of mass in the upper mediastinum. Although there is no clear definition of retrosternal, substernal, or mediastinal goiter in the literature, it usually refers to an extension of thyroid tissue from the cervical part that continues to the anterior mediastinum of the aortic arch. One of the interesting features of these cervical mediastinal lesions is that they may not be continuous. Such goiter types classically present with compression symptoms such as dyspnea, dysphonia, dysphagia, or sleep apnea, and less frequently, these masses can compress neurovascular structures, leading to superior vena cava (SVC) syndrome and Horner’s syndrome. In our case report, A 47-year-old female from North Karnataka presented to the hospital with history of dyspnea, dysphonia, and dysphagia persisting for the last 3 years. After careful examination and investigation, a diagnosis of thymoma was made initially. However, upon biopsy of the excised tumor, unexpected finding was revealed, it was identified as a multinodular goiter (MNG) rather than a thymoma.
Diagnóstico sobre la disponibilidad de información y estadísticas de la gestión integral de residuos sólidos municipales y la economía circular en América Latina y el Caribe
Authors: Alarcón Montero Pablo Andrés , Acosta Acevedo Salvador , Correal Magda , Hernández López Carlos , Piamonte Carolina , Rojas Gutiérrez Arcelia , Fallik Bettina
Published: January 2024

¿Qué información sobre la gestión de residuos en América Latina y el Caribe está disponible para ser consultada? ¿Qué entidad y enlaces en la web albergan dicha información? ¿Existen sistemas de datos y estadísticos en los países de América Latina y El Caribe sobre residuos y economía circular? ¿Qué países lideran la disponibilidad de datos en la región? ¿Qué brechas de datos existen? Esta nota técnica, en el marco del Hub de Residuos Sólidos y Economía Circular, da respuesta a estas inquietudes, al unificar y visibilizar los esfuerzos en América Latina y el Caribe de contar con datos e información sobre gestión de residuos y economía circular. De forma interactiva se pueden explorar los datos e información que hay sobre el sector en la sección de datos y de comunidad del Hub de Residuos Sólidos y Economía Circular.
Analizando la toma de decisiones financieras en una Universidad Virtual
Authors: Quiroga Juárez Christian Arturo , Villalobos Escobedo Aglaé , Cortés Cabrera Alma Ruth
Published: January 2024

El objetivo fue evaluar, la toma de decisiones financieras de una comunidad estudiantil del Estado de Guanajuato. El método es cuantitativo, descriptivo y transversal. Los resultados derivaron en contribuciones significativas desde la perspectiva teórica, comparativa, empírica, y práctica. En conclusión, se identificó cómo la comunidad estudiantil virtual toma sus decisiones financieras proveyendo un escenario cuantificado para gestionar acciones estratégicas educativas.
Research progress and applications of transcritical carbon dioxide heat pumps: A review
Authors: Mei Shengong , Liu Zhongyi , Liu Xia
Published: January 2024

Heat pump technology is an energy-saving technology that can efficiently utilize low-grade energy. It has broad application prospects in building heating, industrial waste heat utilization, new energy and other fields. However, the refrigerants used in traditional heat pump systems have serious negative impacts on the environment, and there is an urgent need to find a safe, environmentally friendly, and efficient alternative refrigerant. As a natural refrigerant, CO2 has good physical and chemical properties and is very suitable as a working fluid in transcritical cycles, showing great advantages in the field of heat pump technology. At present, research on CO2 heat pumps has made certain progress, but there are few reviews of the research status and development trends of CO2 heat pumps in different applications. Therefore, this article systematically summarizes the latest research results of transcritical CO2 heat pumps in different application fields, pointing out the difficulties such as high pressure and low operating efficiency in system design and operation. It also summarizes the latest optimization research on system components, cycle structure, mixed refrigerants and control strategies. The results show that each optimization method can significantly improve system performance, among which mixed refrigerant is the simplest optimization method. Finally, the outlook for CO2 heat pump technology is put forward. With policy support and technological advancement, more comprehensive, energy-saving, and intelligent CO2 heat pump technology will continue to develop and innovate.
Prednosti in slabosti bivanja ter potrebe lokalnih prebivalcev v Svečini, Turnišču in Cirkulanah
Authors: Žagavec Aljaž , Pucko Klemen , Jöbstl Gita , Kumer Peter
Published: January 2024

Raziskava obravnava percepcije in potrebe lokalnih prebivalcev na treh podeželskih območjih. Pri tem smo primerjali mnenja krajanov na eni in strateške načrte, ki so jih v preteklih letih sprejele Lokalne akcijske skupine in Regionalne razvojne agencije, na drugi strani. Rezultati kažejo na razlike in podobnosti med mnenji lokalnega prebivalstva in strateškimi načrti, kar odpira razpravo o učinkovitosti in usmeritvi regionalnega razvoja.
Tourism Gentrification in a Small Mediterranean Town: Impacts and Implications for Urban Climate Resilience
Authors: Kumer Peter , Kralj Erik , Meulenberg Cécil
Published: January 2024

This study explores the relationship between tourism gentrification and urban climate resilience in Piran. It focuses on socio-economic changes due to tourism and their implications for the town's ability to respond to climate-related challenges. Using mixed methods, it evaluates the effects on architectural authenticity, public spaces, and community dynamics. The findings reveal conflicts between heritage preservation and tourism, highlighting integration challenges for newcomers in enhancing climate resilience. The paper advocates for strategies balancing sustainable tourism with cultural heritage preservation, offering solutions for similar towns in the Mediterranean.
Spremembe pozidanih in sorodnih površin v Sloveniji
Authors: Žiberna Igor , Ivajnšič Danijel , Konečnik Kotnik Eva
Published: January 2024

V članku so predstavljene spremembe pozidanih in sorodnih površin v Sloveniji v obdobju 2000-2023. Le-te so analizirane po statističnih regijah in občinah. Posebej so obravnavane izvorne kategorija rabe tal, na katerih se danes nahajajo pozidane in sorodne površine. Dodatno se osredotočamo na širjenje pozidanih in sorodnih površin na obdelovalne površine, predvsem tiste, ki so izjemnega pomena za kmetijstvo in pridelavo hrane.
Foreword to the thematic issue on cities in global capitalism
Authors: Kumer Peter , Davidovič Danijel
Published: January 2024

This thematic issue investigates the complex interactions between urban environments and global capitalism. It includes a range of case studies and theoretical analyses that delve into the effects of global economic forces on urban spaces. The papers explore various topics, such as the transformation of labor markets due to digital capitalism, the impact of economic activities on urban climate resilience, and the challenges of sustainable urban development. The issue highlights the necessity of interdisciplinary approaches to understand and address the dynamic relationship between urban geographies and global economic systems.
Učiteljice in učitelji jezikov o medpredmetnem povezovanju
Authors: Lipavic Oštir Alja
Published: January 2024

Prispevek predstavlja rezultate analize stališč in prakse učiteljev jezikov (n = 281) v zvezi z medpredmetnim povezovanjem z nejezikovnimi predmeti. Pokazalo se je, da se tako povezovanje ne prakticira pogosto, učiteljem manjkata razumevanje pristopa in praksa, čeprav se zavedajo njegove koristnosti, tako za lasten profesionalni razvoj kot tudi za učence. Zaradi pomanjkanja prakse medpredmetnega povezovanja učitelji ne znajo dobro oceniti lastnega prispevka pri njegovi realizaciji ali pa nanj niso nujno pripravljeni. Na konkretne situacije, ki aplicirajo vključevanje medpredmetnega povezovanja, učitelji reagirajo s stališča svojega lastnega predmeta in ne povezave kot celostne perspektive. Ne glede na našteto pa je zaznati pozitivno komponento v odnosu do izobraževanja na področju medpredmetnega povezovanja. V raziskavi so se pokazale regionalne razlike, saj učitelji iz osrednje Slovenije kažejo niz odklonilnih stališč, šibkejše poznavanje in manj izkušenj, kar zadeva medpredmetno povezovanje. Na splošno je raziskava pokazala identične negativne dejavnike in opažanja, ki jih v Sloveniji ugotavljamo že od leta 2001. To kaže, da bi morala šolska politika pripraviti okvir, v katerem bo medpredmetno povezovanje jezikov z nejezikovnimi predmeti zaživelo kot pristop, ki je stalna praksa in ne samo projektno delo ali pa osamel izraz naklonjenosti posameznega učitelja ali šole.
Slikanice kot izhodišče za medpredmetno povezovanje pri poučevanju tujih jezikov v predšolskem obdobju
Authors: Retelj Andreja
Published: January 2024

V prispevku prikazujemo različne možnosti vključevanja slikanic v poučevanje tujega jezika v predšolskem obdobju. Čeprav pouk tujega jezika v slovenskih vrtcih še ni kurikularno opredeljen in sistematično izvajan, je povpraševanje staršev po izvedbi tečajev za mlajše otroke izjemno veliko. Številni vrtci zato s pomočjo zunanjih izvajalcev v običajno plačljivem nadstandardnem programu ponujajo urice v različnih tujih jezikih, pri čemer je angleščina najpogostejša izbira v večjem delu Slovenije. Slikanica je eden od medijev sporočanja, ki je otrokom v predšolskem obdobju zelo blizu, zato lahko predstavlja dobro izhodišče za osnovanje programa učnih ur tujega jezika in skupaj s Kurikulumom za vrtce ponuja možnosti za obravnavo raznolikih tem, ki jih otroci odkrivajo v predšolskem obdobju. V članku predstavljamo kriterije za nabor kakovostnih slikanic, predlagamo nekaj slikanic iz nemškogovorečega prostora, ki omogočajo medpredmetno povezovanje in medpredmetno naravnane učne dejavnosti, primerne za razvijanje jezikovne pismenosti v materinščini in tujem jeziku, ter spodbujajo večjezičnost, in predstavljamo rezultate študentskega projekta, ki je bil izveden v dveh javnih vrtcih.
Content and Language Integrated Learning (Clil) – Just Another Off-Shoot of Communicative Language Teaching or a Post-method Foreign-Language Pedagogy on Its Own Terms?
Authors: Burazer Lara , Skela Janez
Published: January 2024

As the CLIL approach is regularly represented in recently published primary-school English coursebooks used in Slovenia, this paper examines the emerging issues of teaching content in the foreign language classroom. It addresses the question of the extent to which the traditional fragmentation of teaching content has been replaced by integration or fusion between language and content across school subjects. It aims to provide analytical data on whether, and to what extent, the CLIL content has really synthesized past methodologies into a crossover educational paradigm on its own term, and thus replaced fragmentation, or whether it has remained on the level of CLIL ‘pigeonholes’, i.e. occasional CLIL content/activities added haphazardly for the sake of variety. In the analysis, the focus is first on the various definitions of CLIL, which then shifts to the acronym breakdown, offering a unique insight into the CLIL components. In closing, the article encourages the use of the CLIL approach in a systematic and continuous manner, promoting it as a way of incorporating the concept of fusion into the English language classroom, critically recognizing the assumptions and values underpinning CLIL and its methodology as relatable and manageable aspects of effective foreign language instruction.
ODABIR JEZIKA U ISKAZIVANJU EMOCIJA KOD BILINGVALNIH GOVORNIKA: SLUČAJ MAĐARSKOG I SRPSKOG JEZIKA
Authors: Lukić Jelena
Published: January 2024

Posmatrajući bilo koje višejezično društvo, javljaju se pitanja u vezi s temom dvojezičnosti, paralelnog korišćenja maternjeg i drugog jezika i uticaja koji ovi jezici imaju na individuu u procesu iskazivanja emocija. Uprkos sve većem broju istraživanja dvojezičnosti, nije bilo pokušaja da se ova tema obradi imajući u vidu mađarski i srpski kao dva glavna jezika bilingvalnih govornika. Stoga, cilj rada je da se u značajnom obimu shvati veza između bilingvalnih govornika i njihovih jezika pri iskazivanju emocija. U radu je primenjena adaptirana verzija upitnika o bilingvizmu i emocijama (BEQ) uz statističku analizu i intervjue kako bi se stekao uvid u kognitivne procese bilingvalnih govornika. Rezultati sugerišu da pojedinci pokazuju sklonost prema određenom jeziku kada razgovaraju o emocijama i emotivnim temama, zahvaljujući mnoštvu subjektivnih faktora kao što su uzrast savladavanja drugog jezika, kontekst savladavanja, znanje jezika i socijalizacija u jeziku. Iako rezultati daju potporu argumentima razvijenim u radu, oni nisu univerzalno primenljivi i isključivo predstavljaju osnovu za dalja istraživanja u datoj naučnoj disciplini.
FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN PERILAKU PENCEGAHAN COVID-19 SOPIR TRUK EKSPEDISI DI MASA ADAPTASI KEBIASAAN BARU
Authors: Candra Kirana Clarrisa Ayu , Ririaty Mury , Nafikadini Iken
Published: January 2024

Perilaku kesehatan dalam mencegah penularan Covid-19 di masa adaptasi kebiasaan baru merupakan upaya penting yang harus dilakukan oleh masyarakat untuk memutus rantai penularan Covid-19, khususnya bagi individu yang memiliki risiko penularan tinggi seperti sopir truk ekspedisi. Penelitian ini bertujuan untuk mengetahui faktor apa saja yang berhubungan dengan perilaku kesehatan sopir truk ekspedisi dalam upaya pencegahan penularan Covid-19 di masa adaptasi kebiasaan baru. Penelitian ini merupakan penelitian kuantitatif dengan pendekatan korelatif. Populasi dalam penelitian ini adalah anggota sopir truk ekspedisi Komunitas Driver Laros Banyuwangi (KDLB) dengan sampel sebesar 54 sopir. Data primer penelitian ini berupa hasil wawancara dengan kuesioner tertutup dan observasi serta data sekunder berupa dokumen keanggotaan KDLB. Analisis data dilakukan secara univariat dan bivariat menggunakan uji korelasi spearman dengan nilai signifikansi 0,05. Hasil penelitian menunjukkan bahwa variabel pendidikan terakhir (p-value 0,119), lama kerja (p-value 0,295), rute kerja (p-value 0,296), dan ketersediaan sarana dan prasarana (p-value 0,574) tidak berhubungan dengan perilaku pencegahan penularan Covid-19, sedangkan umur (p-value 0,013), pengetahuan (p-value 0,000), dan sikap (p-value 0,041) memiliki hubungan dengan perilaku pencegahan penularan Covid-19. Dinas Kesehatan diharapkan mampu memberikan informasi secara langsung melalui sosialisasi maupun tidak langsung melalui media promosi kesehatan yang disebarluaskan. Sopir truk ekspedisi juga diharapkan mampu menerima dan aktif mencari informasi terpercaya terkait Covid-19.
ANALISIS FAKTOR LINGKUNGAN RUMAH DAN KEBERADAAN JENTIK AEDES AEGYPTI DI KELURAHAN TEBING TINGGI TAHUN 2022
Authors: Chahaya Indra , Indirawati Sri Malem , Salmah Umi , Bukit Dhani Syahputra , Hutagalung Dodi Saputra , Saragih Anggi Andini
Published: January 2024

Kelurahan Tebing Tinggi merupakan salah satu daerah tinggi kasus DBD, sejak Januari hingga September tahun 2022 kasus DBD mencapai 32 kasus. Kondisi lingkungan rumah dapat menjadi faktor pemicu perkembangan Larva nyamuk Aedes Aegypti di wilayah endemis DBD. Tujuan penelitian ini untuk menganalisis berbagai faktor lingkungan rumah masyarakat dan hubungannya dengan kepadatan larva Aedes Aegypti di Kelurahan Tebing Tinggi. Penelitian adalah penelitian kuantitatif dengan desain cross-sectional. Lokasi penelitian di Kelurahan Tebing Tinggi dengan populasi penelitian seluruh rumah tangga. Jumlah sampel yaitu 100 rumah dipilih secara acak dengan rumus slovin. Pengumpulan data, data primer dilakukan dengan wawancara menggunakan kuisioner Kobotoolbox, data sekunder diambil dari data profil Kesehatan Puskesmas Satria. Data dianalisis secara univariat dan bivariat menggunakan uji Chi-Square dengan taraf signifikansi 95%. Hasil Studi menemukan bahwa 34 rumah ditemukan larva nyamuk Aedes Aegypti. Berdasarkan hasil uji statistic dengan uji Chi-Square bahwa variabel Jumlah TPA menjadi satu-satunya faktor lingkungan yang mempengaruhi keberadaan larva Aedes Aegypti di Kelurahan Tebing Tinggi (p value 0,009). Dapat disimpulkan bahwa penanganan lingkungan rumah yang baik dapat dijadikan sebagai tindakan protektif dalam mencegah perkembangan larva Aedes Aegypti di Kelurahan Tebing Tinggi.
PENGETAHUAN DAN IMPLEMENTASI CAREGIVER DALAM PENGASUHAN ANAK ADHD: STUDI KUALITATIF
Authors: Indah Ana Puspita , Arrozaqi Muhammad Rofi , Nirmalajati Budhi , Isidora Ismiyati , Triatmojo Wahyu , Sevriana Ery Surya , Pangestuti Rayi Citra Ayu
Published: January 2024

Gangguan perkembangan saraf yang ditandai dengan kurangnya perhatian, hiperaktif, dan impulsif pada anak, yang disebut Attention Deficit Hyperactivity Disorder (ADHD), menyebabkan anak ADHD menghadapi kesulitan dalam segala aspek kehidupan. Namun, hal ini dianggap sebagai beban bagi anggota keluarga atau orang-orang di sekitarnya. Meskipun demikian, peran keluarga atau caregiver sangat berpengaruh dalam memperbaiki kondisi anak ADHD. Penelitian ini bertujuan untuk menggali pengetahuan caregiver dalam merawat anak ADHD. Penelitian kualitatif dengan wawancara mendalam dilakukan di RSJ Prof. Dr. Soerojo Magelang pada bulan Juni hingga November 2022. Partisipan penelitian dipilih secara purposive sampling dan diperoleh 8 informan yang merupakan caregiver anak ADHD. Pada penelitian ini didapatkan empat tema utama mengenai pengetahuan caregiver dalam mengasuh anak ADHD, meliputi: sumber pengetahuan, definisi dan gejala ADHD, peran caregiver dalam merawat anak ADHD, dan penanganan ADHD. Semua informan tidak memiliki pengetahuan pasti tentang definisi ADHD tetapi mampu mengidentifikasi beberapa gejala dan penyebab ADHD. Informan juga memiliki pengetahuan tentang perannya dan menerapkannya dalam pengasuhan anak ADHD, meskipun mereka seringkali menghadapi beberapa kendala.
Doença de Hansen: Apresentação Incomum de uma Doença Antiga
Authors: Ferreira Mário , Grijó Carlos , Paulo Joana , Fonseca Marta , Neves Zélia
Published: January 2024

A doença de Hansen, vulgarmente conhecida como lepra, é uma doença infecciosa causada por Mycobacterium leprae. Sendo rara nos países desenvolvidos, configura uma doença de importação cada vez mais frequente considerando o fluxo migratório de países onde é endémica. Apresentamos o caso de um homem de 21 anos que recorreu ao serviço de urgência por poliartralgias de caráter aditivo envolvendo grandes articulações, pápulas e placas eritematosas nos membros com bolhas e necrose central e febre com calafrio com uma semana de evolução. Foi realizada biópsia cutânea que revelou infiltrado neutrofílico com granulomas de distribuição perineural e baciloscopia com deteção de bacilos ácido-álcool resistentes. Foi estabelecido o diagnóstico de DH multibacilar com reação lepromatosa tipo 2 (eritema nodoso leproso), apresentando melhoria clínica sob corticoterapia. O eritema nodoso leproso cursa habitualmente com lesões dolorosas, configurando uma apresentação atípica de lepra, sobretudo na presença de bolhas e necrose, tornando este diagnóstico altamente desafiante. O estigma social é frequentemente limitativo na aceitação da doença e adesão ao tratamento.
The mental health impact of COVID-19: the need for community interventions and collaboration for recovery
Authors: Rajeshkannan Nadarajah , Somasundaram Daya , Kumarendran Balachandran , Kumanan Thirunavukarasu , Aloysius Ivan Dinesh , Sugirthan Nalayini , Sasikumar Sivanantham , Jegathesan Nalayini
Published: January 2024

Background: Since 2019, the COVID-19 epidemic has spread across the world, affecting millions of individuals on physical, mental, and socioeconomic levels. Materials and methods: This qualitative study aims to map out the mental health consequences of the COVID-19 pandemic and suggest recovery strategies based on analyzing COVID-19 mental health and psychosocial impact-related comments on social/news media, participant’s observations, and participant action research. The results and suggested recovery strategies were triangulated with literature survey. Results: In COVID sufferers, neuropsychiatric symptoms lasting months were noted while some went on to have a relapse of psychological or neurological conditions. In the general population, common consequences included common mental health disorders, changing patterns of substance abuse particularly alcohol, and increased domestic violence. Family relationships and interactions generally improved but in a minority had strained dynamics. Vulnerable groups included the elderly, women, youth, children, disabled, frontline and health workers, minorities, and severely mentally ill. At the community level, there were signs of collective (mass) hysteria from panic buying to conspiracy theories, public shaming, fake news, and disinformation spreading on social media and mass protests. There were also positive effects such as better understanding of bio-knowledge, interventions and discoveries, online learning, gratitude toward health-care workers, increased community and family cohesion, reduction in road traffic accidents, and drop in other respiratory infections with their resultant morbidity and mortality. Conclusion: Given the widespread mental health consequences of the COVID-19 pandemic, a community-based approach is suggested while treating more severe mental disorders at the primary care or specialist level.
Genetic Diversity of Human Norovirus in Children Less Than 5 Years of Age With Acute Gastroenteritis in Rural Communities in the Gambia
Authors: Jagne Sheriffo , Hossain M. Jahangir , Antoni Martin , Sesay Abdul Karim , Abdul Muhammed Khalie , Mohammed Nuredin I. , Senghore Madikay , Darboe Alansana , Manneh Jarra , Kanteh Abdoulie , Khan Dam , Bah Saikou Y , Peter Ndaw Sylvanus , Quaye Osbourne , Armah George Enyimah
Published: January 2024

The research identified norovirus genotypes that circulated among Gambian children less than five years of age with diarrhoea during 2007-2012. The study highlights the importance of continuous surveillance for detecting the emergence of new norovirus genotypes.
Techniques for Theoretical Prediction of Immunogenic Peptides
Authors: Friedman Robert
Published: January 2024

Small peptides are an important component of the vertebrate immune system. They are important molecules for distinguishing proteins that originate in the host from proteins derived of a pathogenic organism, such as a virus or bacterium. Consequently, these peptides are central for the vertebrate host response to intracellular and extracellular pathogens. Computational models for prediction of these peptides have been based on a narrow sample of data with an emphasis on the position and chemical properties of the amino acids. In past literature, this approach has resulted in higher predictability than models that rely on the geometrical arrangement of atoms. However, protein structure data from experiment and theory are a source for building models at scale, and, therefore, knowledge on the role of small peptides and their immunogenicity in the vertebrate immune system. The following sections introduce procedures that contribute to theoretical prediction of peptides and role in immunogenicity. Lastly, deep learning is discussed as it applies to immunogenetics and the acceleration of knowledge by a capability for modeling the complexity of natural phenomena.
Determining the Availability of Continuous Systems in Open – Pits Using ANFIS and a Simulation Model
Authors: Gomilanović Miljan , Bugaric Ugljesa , Bankovic Mirjana , Stanic Nikola , Stepanovic Sasa
Published: January 2024

This paper presents a model for determining the availability of continuous systems at open pits using the neuro-fuzzy system. The concept of availability is divided into partial indicators (synthetic indicators and sub-indicators). The presented model in relation to already existing models for determining availability uses a combination of the advantages of artificial neural networks and fuzzy logic. The case study was done for the I ECC (bucket wheel excavator – conveyors – crushing plant) system of the open pit Drmno, Kostolac. In this paper, in addition to the ANFIS model for determining the availability of continuous systems, a simulation model was developed. The obtained results of the ANFIS model were verified with the help of a simulation model that uses certain assumptions about the distribution of failures. This paper was created as a result of several years of field and theoretical research into the availability of continuous sys-tems in open-pit mines, and completes a cycle that consists of several published articles on the subject of modeling the behavior of these systems in real time using a time picture of the state, expert assessment, simulation and AI models, respecting the multidisciplinarity of the problem (mining-technological, mechanical, information-technological aspects).
Genomic Insights into Moderately Thermophilic Methanotrophs of the Genus Methylocaldum
Authors: Delherbe Nathalie , Pearce David , But Sergey Y , Murrell J. Colin , Khmelenina Valentina N. , Kalyuzhnaya Marina G.
Published: January 2024

Considering the increasing interest in understanding the biotic component of methane removal from our atmosphere, it becomes essential to study the physiological characteristics and genomic potential of methanotroph isolates, especially their traits allowing them to adapt to elevated growth temperatures. The genetic signatures of Methylocaldum species have been detected in many terrestrial and aquatic ecosystems. A small set of representatives of this genus has been isolated and maintained in culture. The genus is commonly described as moderately thermophilic, with the growth optimum reaching 50oC for some strains. Here, we present a comparative analysis of genomes of three Methylocaldum strains—two terrestrial M. szegediense strains (O-12 and Norfolk) and one marine strain Methylocaldum marinum (S8). The examination of the core genome inventory of this genus uncovers significant redundancy in primary metabolic pathways, including the machinery for methane oxidation (numerous copies of pmo genes) and methanol oxidation (duplications of mxaF, xoxF1-5 genes), three pathways for one-carbon (C1) assimilation, and two methods of carbon storage (glycogen and polyhydroxyalkanoates). We also investigate the genetics of melanin production pathways, as a key feature of the genus.
Filter Cake Neural-Objective Data Modelling and Image Optimization
Authors: Wayo Dennis Delali Kwesi , Irawan Sonny , Satyanaga Alfrendo , Kim Jong , Bin Mohamad Noor Mohd Zulkifli , Rasouli Vamegh
Published: January 2024

Neural-objective and image optimization approaches for drilling fluid rheology automation are crucial for drilling engineering optimization. A myriad of intelligent computational models are employed to predict and monitor the parameters of mud rheology and filter cake permeability posture using an artificial neural network feedforward (ANN-FF) function, a non-ANN-FF function, an image processing tool, and a model optimization tool. 498 datasets of synthetic-based mud (SBM) flat rheology from a drilling mud laboratory at Nazarbayev University were imported into a user-friendly MATLAB application using image processing and nftool. Apart from the Google TensorFlow Sequential API DNN architecture used, a Levenberg-Marquardt training algorithm with input sigmoid hidden neurons 10, 12, and 18 coupled with a linear output layer was also used to predict the SBM flow index. OBM and SBM filter cakes were processed for void spaces; however, a model study was extrapolated to maximize filtration volume Vf. The study’s findings show that the ANN-FF model employed for rheological property monitoring and prediction had higher steady and exponential levels of accuracy and a correlation coefficient of 0.96-0.99. More so, SBM and OBM image processing presented an area of void spaces of 1790M2 and 1739M2, respectively. The porosity and permeability postures of both SBM and OBM resulted in a significant void space capable of maximizing the flow index. In addition, the single-objective modelling based on a genetic algorithm did validate the experimental rheological data for flow index or filtration volume Vf optimization; the study resulted in the finding that the constrained physics-informed objective function hindered maximizing oil recovery and instead predicted possible formation damage. It is empirical to note that automating flow predictions with neural, objective, and image functions has presented an alternative novel method for non-programmers using MATLAB and Google Colabs that is capable of enhancing mud rheological parameters, drilling efficiency, and hydrocarbon recovery.
Pulsed Electromagnetic Fields (PEMFs) Trigger Cell Death and Senescence in Cancer Cells
Authors: Pantelis Pavlos , Theocharous Giorgos , Veroutis Dimitris , Vagena Ioanna-Aglaia , Polyzou Aikaterini , Thanos Dimitris-Foivos , Kyrodimos Efthymios , Kotsinas Athanassios , Evangelou Konstantinos , Lagopati Nefeli , Gorgoulis Vassilis G. , Kotopoulos Nicholas
Published: January 2024

The currently available anti-cancer therapies, such as gamma-radiation and chemotherapeutic agents, induce cell death and cellular senescence not only in cancer cells but also in the adjacent normal tissue. New anti-tumor approaches focus on limiting the side effects on normal cells. In this frame, the potential anti-tumor properties of Pulsed Electromagnetic Fields (PEMFs) through irradiation of breast cancer epithelial cells (MCF-7 and MDA-MB-231) and normal fibroblasts (FF95) were investigated. PEMFs had a frequency of 8 Hz, full-square wave type, magnetic flux density of 0.011 T and applied twice daily for 5 days. Data collected showcases that PEMF application decreases the proliferation rate and viability of breast cancer cells while having the opposite effect on normal fibroblasts. Moreover, PEMF irradiation induced cell death and cellular senescence only in breast cancer cells without any effect in the non-cancerous cells. These findings suggest PEMF irradiation as a novel, non-invasive anti-cancer strategy in combination with senolytic drugs, to eliminate both cancer and the remaining senescent cells while simultaneously avoiding the side effects of the current treatments.
FCAE-DCAC: A Novel Fully Convolutional Auto-Encoder based on Dual Clustering and Latent Feature Adversarial Consistency for Hyperspectral Anomaly Detection
Authors: Zhao Rui , Yang Zhiwei , Meng Xiangchao , Shao Feng
Published: January 2024

With the development of artificial intelligence, the ability of capturing the background characteristics of hyperspectral imagery (HSI) is improved and promising performance in hyperspectral anomaly detection (HAD) tasks is yielded. However, existing methods proposed in recent years still suffer from certain limitations: 1) constraints are lacking in the deep feature learning process in terms of the issue for absence of prior background and anomaly information. 2) hyperspectral anomaly detectors with traditional self-supervised deep learning methods fail to ensure prioritized reconstruction of the background. 3) architectures of fully connected deep network in hyperspectral anomaly detectors lead to low utilization of spatial information and destruction for original spatial relationship of hyperspectral imagery, and disregard spectral correlation between adjacent pixels. 4) hypotheses or assumptions for background and anomaly distributions restrict the performance of many hyperspectral anomaly detectors because the distributions of background land covers are usually complex and not assumable in real-world hyperspectral imagery. With the consideration of above problems, in this paper, we propose a novel fully convolutional auto-encoder based on dual clustering and latent feature adversarial consistency (FCAE-DCAC) for HAD which is carried out in a self-supervised learning-based processing. Firstly, the density-based spatial clustering of applications with noise algorithm and connected component analysis are utilized for successive spectral and spatial clustering to obtain more precise prior background and anomaly information, which facilitates the separation between background and anomaly samples during the training of our method. Subsequently, a novel fully convolutional auto-encoder (FCAE) integrated with spatial-spectral joint attention (SSJA) is proposed to enhance the utilization of spatial information and augment feature expression. In addition, a latent feature adversarial consistency network is proposed to achieve pure background reconstruction with the ability of learning actual background distribution in hyperspectral imagery. Finally, a triplet loss is introduced to enhance the separability between background and anomaly, and the reconstruction residual serves as the anomaly detection result. We evaluate the proposed method on seven groups of real-world hyperspectral datasets, and the experimental results confirmed the effectiveness and superior performance of the proposed method versus nine state-of-the-art methods.
Evaluation of Hospital Antimicrobial Stewardship Programs: Process, Implementation, Impact and Outcomes. Review of Systematic Reviews
Authors: Abdel Hadi Hamad , Eltayeb Faiha , Al Balushi Sara , Daghfal Joanne , Ahmed Faraz , Mateus Céu
Published: January 2024

Background: Antimicrobial Stewardship Programs (ASP) were introduced in healthcare as a public health priority to promote appropriate prescribing of antimicrobials, reduce antimicrobials adverse events as well as control challenges of antimicrobial resistance. To deliver aimed outcome objectives, ASPs involve multiple implementation measures. A review of systematic review was conducted to evaluate ASPs process and outcome measures. Guided by PRISMA frames, published systematic reviews (SR) focusing on ASPs restricted to secondary healthcare were evaluated over the past 10 years by examining major and primary databases involving all age groups. Out of 265 identified SR studies, 63 met inclusion criteria, the majority were conducted in European and North American regions. All age groups were examined in the studies but mainly conducted in adults when compared to children and infants . Both ASPs process and outcomes measures were examined equally and simultaneously through 25 different concepts, dominated by efficacy , antimicrobial resistance , and economic impact while information technology as well as role of pharmacy and behavioural factors were equally examined . The main broad conclusions from the review , that across the globe, ASPs demonstrated effectiveness, proved efficacy, and confirmed efficiency while focused evaluation advocate that developed countries should target medium and small sized hospitals while developing countries should continue rolling ASPs in their healthcare facilities . Additionally , the future of ASPs should focus on embracing evolving information technology to bridge gaps in knowledge, alter attitude and enhance decision making .
Soft-Shell Production of the Invasive Atlantic Blue Crab Callinectes sapidus in the Lesina Lagoon (Se Italy):
Authors: Cilenti Lucrezia , Lago Nicola , Lillo Antonio Oscar , Li Veli Daniel , Scirocco Tommaso , Mancinelli Giorgio
Published: January 2024

The current invasion of the Mediterranean Sea by the Atlantic blue crab Callinectes sapidus entails the implementation of effective strategies of control and management. In native areas, the species is highly appreciated as a hard- and soft-shell seafood, and hard-shell fisheries are developing in a number of invaded countries. Here, to verify alternative approaches for enhancing the commercial value of the species, we carried out a pilot experiment to test a flow-through system for the production of soft-shell blue crabs. Fifty crabs were collected in the Lesina lagoon (Adriatic Sea, Italy) and inspected for the coloration of the line on the distal edge of the fifth pereiopod. Accordingly, they were grouped into three groups showing no, white, and red lines, symptomatic of the progression of the pre-molt phase, and maintained for 31 days in a flow-through pond system. The overall mortality rate determined during the trial was similar across the three groups and ranged between 10 and 20%, indicating that the flow-through system was effective for rearing the crabs. In addition, the molting rate was 10%, 65%, and 85% for individuals at an early, intermediate, and advanced pre-molt stage, confirming that the line coloration can be used as an effective indicator of the advancement of the molting process. Our study provides a first contribution towards the introduction in the Mediterranean fishery sector of novel procedures and practices for the production of soft-shell blue crabs, which may represent a cost-effective strategy to enhance the capture and commercialization of this invasive species as a high quality and valuable shellfish product.