bluuebunny/crossref_metadata_2025 huggingface dataset:
Synthesis and styrene copolymerization of fluoro, iodo, phenoxy, methoxy, and methyl ring-disubstituted 2-methoxyethyl phenylcyanoacrylates
Authors: Cappas Julianne , Caraus Emma , Chandra Sharad , Flores Jacqueline A. , Jorgensen Emily F. , Khan Spozmai N. , Kulka Emilia , Lami Eiden , McGee Grace A. , Sadiku Gazmend , Sakka Rami , Shaban Laith M. , Shaikh Mariam , Rocus Sara M. , Schjerven William S. , Kharas Gregory B
Published: April 2022

Novel ring-disubstituted 2-methoxyethyl phenylcyanoacrylates, RPhCH=C(CN)CO2CH2CH2OCH3 (where R is 2-fluoro-3-methoxy, 2-fluoro-4-methoxy, 2-fluoro-5-methoxy, 2-fluoro-6-methoxy, 3-fluoro-4-methoxy, 4-fluoro-3-methoxy, 2-fluoro-5-methyl, 2-fluoro-6-methyl, 3-fluoro-4-methyl, 4-fluoro-2-methyl, 4-fluoro-3-methyl, 4-fluoro-3-phenoxy, 5-iodo-2-methoxy) were prepared and copolymerized with styrene. The acrylates were synthesized by the piperidine catalyzed Knoevenagel condensation of ring-disubstituted benzaldehydes and 2-methoxyethyl cyanoacetate, and characterized by CHN analysis, IR, 1H and 13C NMR. All the acrylates were copolymerized with styrene in solution with radical initiation (ABCN) at 70C. The compositions of the copolymers were calculated from nitrogen analysis.
Materials Research Directions Towards a Green Hydrogen Economy: A Review
Authors: Baum Zachary , Lotti Diaz Leilani , Konovalova Tatyana , Zhou Qiongqiong
Published: April 2022

A constellation of technologies have been researched with an eye towards enabling a hydrogen economy. Within the research fields of hydrogen production, storage, and utilization in fuel cells, various classes of materials have been developed targeting higher efficiencies and utility. This Review examines recent progress in these research fields from the years 2011-2021, exploring the concepts and materials directions important to each. Particular attention has been given to catalyst materials enabling the green production of hydrogen from water, chemical and physical storage systems, and materials used in technical capacities within fuel cells. Quantification of publication and materials trends provides a picture of the current state of development within each node of the hydrogen economy.
N-Aryl-2-iso-butylmercaptoacetamides: the discovery of highly potent and selective inhibitors of Pseudomonas aeruginosa virulence factor LasB and Clostridium histolyticum virulence factor ColH
Authors: Voos Katrin , Yahiaoui Samir , Konstantinović Jelena , Schönauer Esther , Alhayek Alaa , Sikandar Asfandyar , Si Chaib Khadidja , Ramspoth Tizian , Rox Katharina , Haupenthal Jörg , Köhnke Jesko , Brandstetter Hans , Ducho Christian , Hirsch Anna
Published: April 2022

Antimicrobial resistance is currently one of the serious global public health threats. Unlike the conventional antimicrobial drugs, antivirulence agents disarm rather than kill bacterial pathogens and therefore represent an alternative option to skirt the problem of resistance. Pseudomonas aeruginosa elastase (LasB) and Clostridium histolyticum collagenase (ColH) are extracellular bacterial proteases which play a critical role in the establishment and progression of the respective bacterial infection. In this study, we report the modulation of the α-position of the previously reported N aryl mercaptoacetamide class leading to a new type of highly potent LasB and ColH inhibitors (N aryl 2-iso-butylmercaptoacetamides). In addition to their non-toxicity and high selectivity over several human off-targets, selected derivatives may be considered unprecedented dual inhibitors of both LasB and ColH. Among the prepared derivatives, compound 37 showed the most promising properties: it had a favorable safety profile, maintained the viability and integrity of both skin- and lung-cells treated with P. aeruginosa supernatant, demonstrated in vivo efficacy in Galleria mellonella larvae, and revealed a good volume of distribution and moderate in vivo clearance in mice. Taking together, these results demonstrate that compound 37 is a promising candidate for antivirulence drug development.
The Crucial Role of Solvation Forces in Inter-Nanoplatelet Interactions and Stack Formation
Authors: Petersen Nanning , Girard Martin , Riedinger Andreas , Valsson Omar
Published: April 2022

Semiconductor nanoplatelets can possess desirable optical properties. For example, CdSe nanoplatelets show a high fluorescence quantum yield, a large one- and two-photon absorption cross section, and the ability to emit polarized light. However, their usage in devices requires control over their self-assembly, particularly the formation of stacks. The interplay of the various forces leading to stack formation in experiments remains unclear. Here, we use coarse grained molecular dynamics simulations of nanoplatelets in octane solvent to investigate the role of solvation forces in nanoplatelet interactions. We demonstrate that solvation forces resulting from solvent layering are sufficiently strong to stabilize nanoplatelet stacks. We examine the dependence of solvation forces on the nanoplatelets' ligand shell, size, and other parameters. In particular, we demonstrate that for sufficiently large nanoplatelets, solvation forces are proportional to the interacting facet area, and their strength is intrinsically tied to the softness of the ligand shell. The solvation forces exhibit an oscillatory nature; increases in their strength leads to a stronger attraction between close nanoplatelet facets and in addition to an increase in the kinetic barriers.
Permutation-Invariant-Polynomial Neural-Network-based Δ-Machine Learn-ing Approach: A Case for the HO2 Self-reaction and its Dynamics Study
Authors: Liu Yang , Li Jun
Published: April 2022

The potential energy surface (PES) plays a central role in chemistry. As the size of the reaction system increases, it would be more and more difficult to develop its globally accurate full-dimensional PES. One unavoidable difficulty is that it is too expensive to calculate electronic energies of ample configurations for complicated reactions. Δ-machine learning is a highly cost-effective method as only a small number of high-level ab initio energies are required to improve a potential energy surface (PES) fit to a large number of low-level points. Here, we propose a permutation-invariant-polynomial neural-network (PIP-NN)-based Δ-machine learning approach to construct full-dimensional accurate PESs for complicated reactions. The approach is applied to the HO2 + HO2 → H2O2 + O2 reaction, a key process in combustion and atmosphere. The full-dimensional triplet state PES is constructed with a large number of density functional theory (DFT) points, which cover all dynamically relevant regions. Only 14% of the DFT dataset are used to successfully bring the DFT PES to the UCCSD(T)-F12a/AVTZ quality. On this PES of high quality, quasi-classical trajectory (QCT) calculations are performed to study the dynamics of the title reaction. A surprising mode-speciﬁc dynamics is observed, in which exciting a spectator mode leads to significant enhancement of the reactivity at low collision energy. This special mechanism can be attributed to increased attraction potential caused by the excited spectator mode. Such mode specificity may be quite prevalent in free radical reactions involving HO2, which is common in combustion and atmosphere.
Extreme Extensibility in Physically Crosslinked Nanocomposite Hydrogels Leveraging Dynamic Polymer-Nanoparticle Interactions
Authors: Grosskopf Abigail K. , Mann Joseph L. , Baillet Julie , Lopez Hernandez Hector , Autzen Anton A. A. , Yu Anthony C. , Appel Eric A.
Published: April 2022

Designing yield stress fluids to exhibit desired functional properties is an integral challenge in many applications such as 3D printing, drilling, food formulation, fiber spinning, adhesives and injectable biomaterials. Extensibility in particular has been found to be a highly beneficial characteristic for materials in these applications; however, few highly extensible, high water content materials have been reported to date. Herein we engineer a class of high water content nanocomposite hydrogel materials leveraging multivalent, non-covalent, polymer-nanoparticle (PNP) interactions between modified cellulose polymers and biodegradable nanoparticles. We show that modulation of the chemical composition of the PNP hydrogels controls the dynamic crosslinking interactions within the polymer network and directly impacts yielding and viscoelastic responses. These materials can be engineered to stretch up to 2000% strain and occupy an unprecedented property regime for extensible yield stress fluids. Moreover, a dimensional analysis of the relationships between extensibility and the relaxation and recovery timescales of these nanocomposite hydrogels uncovers generalizable design criteria that will be critical for future development of extensible materials.
Identification of a short ACE2-derived stapled peptide targeting the SARS-CoV-2 Spike protein
Authors: Calugi Lorenzo , Sautariello Giulia , Lenci Elena , Trabocchi Andrea
Published: April 2022

The design and synthesis of a series of peptide derivatives based on a short ACE2 alpha-helix 1 epitope and subsequent [i - i+4] stapling of the secondary structure resulted in the identification of a 9-mer peptide capable to compete with recombinant ACE2 towards Spike RBD in the micromolar range. Specifically, SARS-CoV-2 Spike inhibitor screening based on colorimetric ELISA assay and structural studies by circular dichroism showed the ring-closing metathesis cyclization being capable to stabilize the helical structure of the 9-mer 34-HEAEDLFYQ-42 epitope better than the triazole stapling via click chemistry. The results are preliminary for the development of small molecule stapled peptides capable of blocking the key ACE2-Spike S1 protein-protein interaction.
PERBANDINGAN KINERJA KEUANGAN BANK SYARIAH DAN BANK KONVENSIONAL DI INDONESIA (STUDI KASUS PADA PT. BANK MUAMALAT DAN PT. BANK MANDIRI)
Authors: Mardewi Putri , Mansyur Fakhruddin , Nuhung Mahmud
Published: April 2022

This research aims to compare the financial performance of Bank Muamalat and Bank Mandiri in Indonesia in the 2011-2015 period using financial ratios. The financial ratio used consists of CAR, ROA, LDR, NPL, and BOPO. The data used in this study is obtained from the Published Financial Reports issued by each of the Banks concerned. The analysis technique used to see a comparison of the financial performance of Bank Muamalat and Bank Mandiri is a comparative research method that is comparative in nature. The analysis conducted shows that there are significant differences for each financial ratio between Bank Muamalat and Bank Mandiri in Indonesia. Bank Muamalat has better performance in terms of LDR and BOPO ratios, while Bank Mandiri has better performance in terms of CAR, ROA and NPL ratios.
ANALISIS MEKANISME DAN PENERAPAN PENGELOLAAN DANA PENSIUN SYARIAH TERHADAP FATWA DSN-MUI NOMOR 88/DSN-MUI/XI/2013 PADA BANK SYARIAH CABANG TAMALANREA
Authors: Nuhung Mahmud , Hidayat Hidayat
Published: April 2022

This study aims to determine the Mechanism and Implementation of Shariah Pension Fund management regarding the MUI DSN Fatwa Number 88/DSN-MUI/XI/2013 in Bank Syariah Mandiri. This research is a case study research with a qualitative descriptive approach. The Sharia Pension Fund Management Mechanism at Bank Syariah Mandiri is manageable, which starts with salary transfer by Bank Syariah Mandiri to PT TASPEN, then the Customer can choose Sharia Pension Fund Services at Bank Syariah Mandiri with the choices of Payroll Partners using the Mudharabah Muthlaqah Agreement or Financing using the Murabahah Agreement or Ijarah Agreement. The Application of Sharia Pension Fund Management satisfies the Fatwa of MUI DSN Number 88 / DSN-MUI / XI / 2013 unless at the Term of PT TASPEN and Customer.
ANALISIS KOMPORASI TINGKAT PENGEMBALIAN, RISIKO DAN KOEFISIEN VARIASI PADA SAHAM SYARIAH DAN SAHAM KONVENSIONAL DI LQ45
Authors: Haanurat Ifayani , Razak Linda Arisanty , Awaliah Eni Versary
Published: April 2022

This study aims to examine the comparison of returns, risks and coefficient of variation in sharia and conventional companies in LQ45. The sample collection method uses the Purpose Sampling method, namely the selection of samples based on certain criteria so that each of the 4 Islamic and conventional shares is obtained. The technique used is the independent sample T test. Based on the results of the study indicate that there is no significant difference between the rate of return, risk and coefficient of variation in Islamic and conventional companies in LQ45Keywords: Returns, Risk, Variation Coefficient, Sharia Shares, Conventional Shares, LQ 45
PERSPEKTIF PEMILIK USAHA RUMAH KOS TENRANG PEMAHAMAN PAJAK HOTEL TERKAIT PENINGKATAN PENDAPATAN ASLI DAERAH KOTA MAKASSAR
Authors: Rustam Andi , Rasulong Ismail , Nursyafirah Indri
Published: April 2022

The purpose of this study is to determine the perspective of boarding house business owners regarding their understanding of the boarding house category hotel tax in Makassar City. This type of research is a qualitative descriptive study. Data collection techniques using literature study, observation, interviews and documentation. Data analysis techniques used data reduction, data presentation, and drawing conclusions. The results of this study indicate that the perspective of boarding house business owners regarding the hotel tax in the boarding house category is still lacking due to the lack of socialization from the government and the hotel tax rate for the boarding house category is still considered burdensome, causing tax avoidance.
Harvest maturity affects the quality and storage behavior of white-fleshed
dragon fruit [Hylocereus undatus (Haworth) Britton and Rose]
Authors: Franco R.K.G. , Esguerra E.B. , Tababa J.L. , Castro A.C.
Published: April 2022

Depending on the buyer’s demand, dragon fruit is harvested at three maturity stages which
may affect the quality and storability of the fruit. This study was conducted to determine
the physico-chemical changes at harvest and during low-temperature storage of whitefleshed dragon fruit harvested at 31, 33, and 35 days after anthesis (DAA). The fruit was
then stored at 5ºC for 5 weeks or at 13ºC for 3 weeks followed by post-storage at 20ºC. At
harvest, fruit harvested at 35 DAA had the highest value of TSS/TA ratio, while 31 DAA
fruit had the highest total phenolic content. Dragon fruit harvested at 33-35 DAA can be
stored at 5°C for three weeks with post-storage life of 9 days at 20ºC. Fruit harvested at 31
DAA exhibited flesh translucency after three weeks at 5ºC, an indication of chilling
injury. When stored at 13ºC, the fruit was of good quality for 2 weeks regardless of
maturity with a shelf life of 5 days for 31 and 33 DAA and only 3 days for 35 DAA.
Physico-chemical changes did not vary significantly during storage at 5ºC and 13ºC
except for the marked decrease in acidity in all maturity stages. When presented to
sensory panellists, preference was higher in fruit harvested at 35 DAA than at 33 and 31
DAA. All things considered, the best harvest maturity stage for prolonged storage at 5ºC
is 35 DAA, while 31-33 DAA for 13ºC storage.
The effect of the addition of chicken feet flour to crispy corn on energy density
and nutritional quality
Authors: Hadi N.S. , Yulianingsih E. , Labatjo R. , Setiawan D.I. , Domili I. , Anasiru M.A. , Arbie F.Y. , Goi M. , Amalia M.R. , Misnati M.
Published: April 2022

Maize contains several essential nutrients that are well-known for their contribution to
food studies. This crop is an alternative carbohydrate source. Considering the increase in
maize production and health advantages, it is the right decision to utilize the crop as an
ingredient of snacks, such as crispy maize. Chicken feet are rich in collagen and protein.
Despite the unpopularity, chicken feet contain nutrition that helps the growth and
development of children. The present study was devoted to analyze the nutrient content of
crispy corn. Relying on an experimental method, the treatment was done by substituting
chicken feet flour on crispy corn; it consisted of five treatment levels with three
replications. The quality of the crispy corn with chicken feet flour was assessed
objectively in a laboratory by doing some analytical methods, including proximate
analysis, energy analysis, calcium analysis, dietary fibre analysis, and iron analysis. Data
analysis procedures were carried out to examine the effect of chicken feet flour on the
snack's chemical quality. This process involved the ANOVA test and LSD test. The
results showed that the addition of chicken feet flour enhanced the nutritional value of the
crispy corn product; this is seen in the rise in the content of energy, protein, fat, water, and
ash. The most recommended formula is F3, the crispy corn with 45 g of chicken feet flour.
Impact of Firm-Specific Factors on the Stock Prices: New Insight from Emerging Market of Asia
Authors: Nazir Yusra , Hussain Farheen Zahra , Mukhtar Ariba , Khalid Samina
Published: April 2022

Purpose: The purpose of this paper is to investigate the factors that can influence the share prices of listed firms. 

Design/Methodology/Approach: The sample of 120 listed firms was selected from 2014–to 202020 was collected.

Findings: We documented a new insight that all the variables have a strong relationship between variables with the share prices except leverage. The ROA and Leverage show a negative relationship with the share price and EPS, dividend per share, firm size and price-earnings ratio show a positive relationship with the share prices. 

Implications/Originality: This paper contributes to the existing literature and continuing debate about firm-specific determinants influencing share price in an emerging market, with a focus on manufacturing firms of Pakistan.
Studies on syntheses, crystal structures, DFT calculation and anti-breast-cancer activities of arteminsin-purine hybrids
Authors: Ding J. , Li B.-Q. , Zeng C.-G. , Song Y.-Y. , Xia K. , Ai Y. , Zhu J.-J. , Zhong H. , Zhou Z.-X.
Published: April 2022

A pair of C9-C10-trans-C10-artemisinin-purine hybrids (A and B) were stereoselectively synthesized under a protonic acid condition, which were structurally characterized by 1H NMR, 13C NMR, IR, HRMS and single crystal X-ray diffraction. Further structural analyses were conducted by Density Functional Theory (DFT) Calculation. DFT-optimized structures of A and B were consistent with X-ray data, so were DFT-based molecular vibrations with IR data. Intramolecular hydrogen bonds played significant role in stabilization of crystal structures both A and B which were chemical stable. Finally, antiproliferative effects of A and B were evalua­ted in human breast cancer cell lines T47D and MDA-MB-436. The anticancer activities of two novel compounds were equivalent to the positive control (mercaptopurine) towards the ER+ cell line T47D, while A was more potent than the positive control in triple-negative-type MDA-MB-436 cells.
Assessment of territory’s provision with oil pipeline and oil product pipeline infrastructure
Authors: Кирсанова Ирина Юрьевна
Published: April 2022

Важнейшая роль нефтяной отрасли в экономике России, задачи обеспечения энергетической безопасности, укрепления геополитических позиций государства, перспективы увеличения экспорта жидких углеводородов обуславливают стратегическую значимость эффективного функционирования и развития отечественной системы трубопроводного транспорта нефти и нефтепродуктов. Теоретические основы и методика оценки транспортной обеспеченности территорий давно находятся в фокусе научных и прикладных исследований. Однако вопросы обеспеченности транспортной инфраструктурой нефтяной отрасли изучены недостаточно, что определяет актуальность и цель настоящего исследования. В рамках исследования рассмотрены используемые в мировой практике методы оценки транспортной обеспеченности территории, обоснована необходимость их адаптации применительно к нефтяной отрасли, разработан методический подход, позволяющий оценить обеспеченность территории нефтепроводной и нефтепродуктопроводной инфраструктурой. Проведен сравнительный анализ транспортной обеспеченности для транспортировки нефти и нефтепродуктов стран - крупнейших производителей нефти, сделан вывод о наличии потенциала развития нефтепроводной и нефтепродуктопроводной инфраструктуры в России.

Scientific and applied researches have focused on the theoretical basis and methods for assessment of territory’s transport provision for a long time. However, issues of transport infrastructure provision in the oil industry have not been studied sufficiently yet. So, it determines the relevance of the research. The crucial importance of the oil industry for the Russian economy makes it important to ensure the effective functioning and development of the domestic pipeline transport system for oil and oil products. The study reviews the methods used in the world practice to assess a territory’s provision with transport infrastructure, proves the necessity to adapt them to the oil industry and develops a methodological approach to assess the territory’s oil pipeline and product pipeline infrastructure. Comparative analysis of provision with oil pipeline and oil product pipeline infrastructure was carried out for the largest oil-producing countries, it allows drawing a conclusion about endless potential for the oil pipeline and oil product pipeline infrastructure development in Russia.
Women and Corruption in Indonesia (Phenomenological Study of the Role and Position of Women in Eradicating Corruption)
Authors: Wulandari Astri , Nugroho Catur , Akbari Rana , Nastain M
Published: April 2022

The case of corruption in Indonesia is an old issue that has caught the attention of the Indonesian people until now. Corruption occurs when public money or state money is not used in accordance with the will of the people and is not allocated properly. This paper seeks to reveal the position and role of women in eradicating corruption in Indonesia. The existence of women in politics can be seen clearly with the increase in the number of women's participation in politics. Women began to show their potential, qualities and convince the public that they could bring about positive changes in government. The role of women in government and politics is followed by the increasing number of women who are suspects and convicted of corruption cases in Indonesia. The research uses a qualitative method with a phenomenological approach and data obtained from in-depth interviews, focus group discussions, and in-depth studies of the results of a survey of women's perceptions of corruption in Indonesia. The results of the study show that in several corruption cases, women often become objects or victims and are also perpetrators of corruption. Women in Indonesia also consider corruption as a common thing that has even become a culture in people's lives. The position of women in corruption can be divided into four positions, namely as an object, abject, anti-subject, and subject. The role of women is very important in the anti
THEORETICAL APPROACHES TO CRISIS MANAGEMENT DURING THE INFORMATION WAR
Authors: Mykhailova Yelyzaveta , Mykhailov Stanislav
Published: April 2022

The study is devoted to crisis management in information warfare. Modern society, transformed into an information society, together with access to information and knowledge has received new threats to personal and national security. Information and communication are realized in the information space, which is a social or geographical space within which typical communication processes take place. Its subjects are individuals, social groups and organizations, and its objects are information or those who receive this information. The field of information warfare is constantly expanding, but its main part remains the media and the Internet. The purpose of the research is to describe and analyze the methods of crisis management of any organization in conditions of information warfare. Methodology. Since crisis management is seen as a process of interrelated functions, at the pre-crisis stage of its formation it is necessary to find out the factors that can prevent a crisis situation, to develop strategic business marketing plans, control risk factors to avoid possible losses and negative consequences. When developing strategies and management methods that prevent a crisis situation (pre-crisis management), preference is given to factors and tools that can activate the exit from the crisis (crisis management), and then to strategies aimed at renewal and post-crisis management systems. Results. Considering that information warfare is universal and can be implemented in all spheres of life, including economic, it affects the efficiency of the enterprise. In such a situation anti-crisis management is used, the purpose of which determines its stages: planning of strategies and programs; organization of optimal structure; motivation of personnel; control of timely changes. In accordance with the purpose of crisis management, its positive results can be observed in: restoring the financial equilibrium of the enterprise; alignment of imbalances of internal and external parameters of the enterprise; ensuring the financial stabilization of enterprises; ensuring and maintaining the viability of the enterprise. Another aspect of crisis management is public administration, which is implemented in the creation of a system of interaction between the state and the market economy, with the ability to overcome macro- and microeconomic crises, provided through financial and legislative regulation, industrial policy and income redistribution.
THE ROLE OF AGRO-INDUSTRIAL ASSOCIATIONS IN INDUSTRIAL AGRICULTURE
Authors: Tymkovan Vladyslava
Published: April 2022

The subject of the study is agroindustrial associations and their role in the industrial agriculture of Ukraine. During the study the following research methods were used: empirical, theoretical methods, as well as observation, analysis and synthesis. The purpose of the study is to analyze the state of the enterprises-participants of agro-industrial associations to identify positive or negative trends in the sustainable development of their activities and to provide suggestions for their further effective development. The relevance of the topic is confirmed by the need to ensure food security of Ukraine, which can be supported primarily by enterprises of agro-industrial complex. The study analyzed the volume of products produced by agricultural enterprises and compared the size of the costs of agricultural production and the amount of net profit of enterprises. It was concluded that the sustainable development of agro-industrial enterprises has declined. To improve these indicators, the authors proposed a number of measures that would help enterprises to get out of the pre-crisis state, namely, state support in various manifestations. The study "Support for Agrarian and Rural Development" within the framework of the project of the United States Agency for International Development (USAID) was also taken into account. The study examined in detail the external and internal negative factors affecting on the activities of agro-industrial associations.
FINANCIAL MARKET OF UKRAINE: STRUCTURE AND DEVELOPMENT TRENDS
Authors: Berzhanir Inna
Published: April 2022

The purpose of this work is to study the current state and trends in the financial market of Ukraine. Methodology. The following methods of scientific research were used: analysis and synthesis; theoretical generalization; abstraction and comparison; systematic approach. Results. The article reports that the financial market of Ukraine is in the process of formation, which is due to the uneven spatial dynamics of financial capital in the course of market reforms; heterogeneity of economic and financial space of the country; fundamental asymmetry between regions in terms of financial capacity; localization of financial institutional infrastructure; level of investment attractiveness, etc. It was found that the main problem of the financial market of modern Ukraine is the inability to provide an effective redistribution of financial resources needed to meet the challenges of modernizing the domestic economy and create an innovative impetus to the reproductive processes. Practical implications. To improve Ukraine's financial sector and boost economic growth, it is necessary to create an effective mechanism for improving banks' lending policies. To develop bank lending and create financial stability in this period it is necessary to make banking services of higher quality to improve their competitiveness; to set maximum interest rates on loans within the framework of state acts and monitor their implementation; to encourage commercial banks to lend to innovative projects; to increase the size of main assets of state banks, increase their number and strengthen their role in the financial and credit market of Ukraine, etc. Value/originality. It has been researched that the structure of the financial market is dominated by the number of companies engaged in the provision of loans, loans, financial leasing, the provision of guarantees; carrying out factoring, currency exchange and money transfer operations. For the development of bank lending it is necessary to improve banking services to improve their competitiveness; set maximum interest rates on loans within state acts and monitor their implementation; stimulate lending by commercial banks to innovative projects; increase capital resources of state banks, increase their number and strengthen their role in the financial and credit market of Ukraine, etc. These measures will contribute to the recovery of the national economy and increase the level of financial efficiency of the domestic banking system.
FORMATION OF BUSINESS STRUCTURES IN THE CONTEXT OF PANDEMIC TRANSFORMATIONS
Authors: Shatskaya Zorina
Published: April 2022

The purpose of the work is to study the process of formation of business structures in different regions of the world in the pre-pandemic and pandemic periods. The object of the study is the process of formation of business structures as integrated subjects of the global network economy. Methodology. The study uses the systematic method of cognition of processes and phenomena in their interconnection and development, as well as methods of statistical analysis used in the analysis of the formation of business structures in the pre-pandemic and pandemic periods. The results of the study reveal the features of the formation of new integration formations of network economy - business structures, which are understood as a complex open integrated system functioning in a dynamic globalized environment based on a combination of material and immaterial interests of member companies to accelerate joint development by accelerating the commercialization. joint innovation activities. It was found that the formation of business structures has become a modern global trend resulting from mergers and acquisitions (M&A) of several enterprises. Practical implications. The practical results of the study allow us to analyze the formation of global business structures in the pre-pandemic period (2015-2018) and the pandemic period (2019-2020). Thus, in the pre-pandemic period there was an annual increase in the number of global business structures by an average of 5%. However, their value in 2018 compared to 2015 decreased by 5.85% to USD 0.449 trillion. The number of global business structures in the regional aspect for 2015-2020, despite the impact of the COVID-19 pandemic, increased annually only in North America (8.4% in 2020 compared to 2015). Other regions of the world saw an annual decline in the number of business structures. It was found that since 2019, due to the impact of the COVID-19 pandemic, the number and value of business structures in the world has continued to decline, which has become rapid. The annual decline in the number of global business structures during the 2019-2020 pandemic averaged 6.37%, and the annual decline in their value averaged 33.19%. The regions that lost the most business during the 2019-2020 pandemic were Western Europe (2%), Southeast Asia (1.2%), and Eastern Europe (0.8%). Value/originality. The value of the study lies in the fact that it allows to analyze global trends in the formation of business structures in the pre-pandemic and pandemic periods and to identify further prospects for their formation in different regions of the world, given the rapid decline in the number of business structures in the world.
Medicinal plant affected respiratory, gastrointestinal, vascular and uterine smooth muscle contractility
Authors: Ali Esmail Al-Snafi
Published: April 2022

In the current review, PubMed, Web Science, Science Direct, and Scopus were searched to investigate the medicinal plants which contracted or relaxed the respiratory, gastrointestinal, vascular and uterine smooth muscles with emphasis on their mode of action.
Breastfeeding in the context of Covid19: Benefits for mothers
Authors: Iliadou Maria  , Potamianou Irene  , Askeridou Georgia
Published: April 2022

Coronavirus 19 disease can cause short as well as long-term effects on human health and function. In particular, its response measures affect breastfeeding and pregnant women in general, resulting in a variety of issues such as changes in breastfeeding practices and increased stress levels. However, the World Health Organization (WHO) recommends exclusive breastfeeding at least for the first six months of a child's life, even if the mother herself is ill, and only if her health condition allows it. In this paper, we provide general information about Covid 19 disease, how it affects breastfeeding, and what benefits will be visible to the breastfeeding mother in a direct or indirect way.
Optimalisasi Ektraksi Ikan Sidat Dengan Variasi Metode Ektraksi sebagai Bahan Baku Pembuatan Mikrokapsul Suplemen Kesehatan Jantung
Authors: Faoziyah Anita Ratna , Issusilaningtyas Elisa
Published: April 2022

Ikan sidat merupakan ikan yang memiliki nilai gizi tinggi. Penelitian ini bertujuan mengetahui optimalisasi ektraksi ikan sidat dan formulasi pembuatan mikroenkapsul ektrak ikan sidat. Metode yang digunakan terdiri dari tiga metode ektraksi yaitu sokletasi, wet-, dan dry rendering. Rendemen ekstrak ikan sidat metode wet-, dry rendering, dan sokletasi masing-masing sebesar 0,019; 8,75; dan 2,41%. Karakteristik ekstrak ikan sidat metode wet rendering berupa minyak ikan dengan warna kuning, berbau amis khas minyak ikan, dengan kandungan air, bilangan peroksida, dan  bilangan asam sebesar 5,3%, 5,8 mg O2/gr, dan 2,8  mg NaOH/gr. Pada metode dry rendering ekstrak berwarna kuning keemasan, jernih dan berbau amis dengan bilangan asam sebesar 1,53 mg NaOH/gr, bilangan peroksida 61,44 mg O2/gr dan angka penyabunan sebesar 353,011 mg KOH/gr. Rendemen ekstrak ikan sidat dengan metode sokletasi berwarna coklat dengan bilangan peroksida sebesar 67,35 mg O2/gr dan bilangan asam 6,67 mg NaOH/gr. Ekstrak ikan sidat dapat dibuat mikroenkapsul kaya omega-3 sebagai suplemen kesehatan jantung koroner dengan formulasi ektrak ikan sidat 10%, amilum maydis 10%, primojel 4%, Mg Stearat - Talk (1 : 9) 1,5%, dan laktosa. Hasil formulasi menujukan kadar air 3,3%; waktu alir 7,23 gram/detik, sudut istirahat 25,44%, dan indeks pengetapan 9,30.
Analisis Hubungan antara Kualitas Pelayanan dan Kepuasan Pasien Rawat Jalan Instalasi Farmasi Rumah Sakit Universitas Muhammadiyah Malang
Authors: Susanto FX Haryanto , Simbolon Nancy Isnawati , Monica Eva
Published: April 2022

Pelayanan kefarmasian yang baik diharapkan dapat mempengaruhi dan membentuk kualitas pelayanan serta kepuasan pasien yang baik pula. Hal ini menyangkut kepentingan rumah sakit itu sendiri berdasarkan kualitas pelayanan yang telah mereka jalankan selama ini. Tujuan dari penelitian ini adalah untuk mengetahui bagaimana hubungan antara kualitas pelayanan dan kepuasan pasien rawat jalan Instalasi Farmasi Rumah Sakit Universitas Muhammadiyah Malang (IFRS UMM) berdasarkan lima dimensi kualitas pelayanan. Penelitian ini dilakukan di RS UMM. Output yang diharapkan dari penelitian ini yakni mengetahui pengaruh dari lima dimensi kualitas pelayanan yakni tangibles (berwujud/ fisik), reliability (keandalan), responsiveness (ketanggapan), assurance (kepastian/ keyakinan) dan empathy (empati) terhadap kepuasan pasien. Penelitian ini dilakukan menggunakan metode kuantitatif. Penelitian kuantitatif ini menggunakan 100 responden dan diolah menggunakan regresi linear berganda yang berguna untuk melihat pengaruh kualitas pelayanan terhadap kepuasan pasien. Hasil penelitian statistik menunjukkan bahwa secara uji simultan, uji parsial maupun koefisien determinasi (R2) kelima dimensi mutu kualitas pelayanan berpengaruh positif terhadap kepuasan pasien, dimana hasil dari uji simultan adalah 18,843 (0,000). Hasil dari uji parsial pada dimensi tangibles adalah 2,451 (0,016), pada dimensi reliability adalah 4,349 (0,000), pada dimensi responsiveness adalah 2,105 (0,038), pada dimensi assurance adalah 2,241 (0,027) dan pada dimensi empathy adalah 2,177 (0,032). Koefisien determinasi (R2) adalah 0,501, yang berarti jika kualitas pelayanan kefarmasian di instalasi farmasi rawat jalan mengalami peningkatan maka berpengaruh pula terhadap kepuasan pasien di instalasi farmasi rawat jalan tersebut.
Uji Aktivitas Antioksidan Masker Gel Peel-off Ekstrak Etanol Kelopak Bunga Rosela (Hibiscus sabdariffa L.) dengan Metode DPPH (1,1-Diphenyl-2-picryhydrazyl)
Authors: Ambari Yani , Fitri Syafiatul , Nurrosyidah Iif Hanifa
Published: April 2022

Masker gel peel off merupakan kosmetik yang digunakan untuk perawatan kulit wajah berbentuk gel. Masker gel peel off kelopak bunga rosela (Hibiscus sabdarifa L.) mengandung senyawa antosianin yang berkhasiat sebagai antioksidan. Penelitian ini bertujuan untuk mengetahui aktivitas antioksidan masker gel peel off dari ekstrak etanol kelopak bunga rosela dengan metode DPPH. Ekstrak etanol kelopak bunga rosela yang digunakan sebagai bahan aktif pada pembuatan masker gel peel off dengan konsentrasi ekstrak etanol kelopak bunga rosella sebesar 0,5% (F1), 0,7% (F2), dan 1% (F3). Uji aktivitas antioksidan dilakukan dengan menggunakan metode DPPH. Hasil uji aktivitas antioksidan menunjukkan bahwa formula masker gel peel off ekstrak etanol kelopak bunga rosela dapat memberikan aktivitas antioksidan. Aktivitas antioksidan yang paling tinggi adalah masker gel peel off dengan konsentrasi ekstrak etanol kelopak bunga rosela sebesar 1% (F3) dengan nilai IC50 sebesar 22 ppm dan nilai AAI sebesar 4,54. Sedangkan aktivitas antioksidan rendah adalah masker gel peel off dengan konsentrasi ekstrak 0,5% (F1) dengan nilai IC50 sebesar 50,53 ppm dan nilai AAI sebesar 1,97%. Semakin tinggi konsentrasi ekstrak etanol kelopak bunga rosela pada sediaan masker gel peel off maka aktivitas antioksidannya akan semakin kuat.
ESTIMASI KOMPONEN RAGAM DAN HERITABILITAS BOBOT BADAN PERIODE STARTER AYAM LOKAL
Authors: Saputra Ahmad Bayu , Papilaya Bercomien J. , Rajab Rajab
Published: April 2022

This study aims to determine the diversity and heritability components of the nature of body weight production of local chickens aged 0-4 weeks. The material used in this study were 95 local chickens from 4 male and 20 female. Heritability calculation (h2) uses the nested design method. The results showed the value of heritability (h2) DOC weights in male body weights were 0.429851 and 0.569476 in the third week, while the largest variance component in the third week was 12.28387 and for female in the fourth week was 59.333934 . Heritability (h2) DOC weights for male body weight gain were 0.6840 and 0.5257 in the third week, the variance component given from the largest male was in the fourth week ie 0.39037 and for female in the second week was 0.68931.
Decolonialidade e resistência nos processos culturais, de fé e de cura na região das Missões do Rio Grande do Sul
Authors: Silva Juliani Borchardt da , Canabarro Ivo dos Santos
Published: April 2022

O presente artigo aborda numa perspectiva decolonial e intercultural as tradições culturais e religiosas na comunidade miguelina - Região das Missões no estado do Rio Grande do Sul. Num primeiro momento é apresentada uma discussão teórica contemplando os conceitos chaves de decolonidade e interculturalidade. Em um momento posterior esses conceitos são aplicados a um estudo empírico na localidade supracitada, trazendo dados pesquisados a partir de depoimentos e imagens fotográficas coletadas no respectivo contexto. Como resultado podemos constatar a importância dos estudos que procuram resgatar dados culturais significativos das comunidades originais. A metodologia utilizada é a crítico histórica, pois analisou-se os conceitos empregados e os dados empíricos para a construção do artigo.
Dissertações e Teses (2021)
Authors: Programa de Pós-Graduação em História (PPGH/UFGD)
Published: April 2022

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Beleza das matas e a sujeira das cidades
Authors: Santos Bruno Silva
Published: April 2022

Durante um ato político em frente ao Fórum da Justiça Federal, na Av. Paulista (São Paulo/SP), duas jovens não indígenas comentam sobre como os Guarani ali presentes estariam “sujos” e “cheios de terra”. Ao compartilhar essas falas com meus interlocutores, tal olhar discriminatório é rebatido a partir de uma complexa crítica indígena ao modo de vida não indígena, descrito, sobretudo, a partir da sujeira que caracteriza a cidade e as criaturas que nela vivem – principalmente, os ratos. O objetivo desse artigo é, partindo dessa crítica indígena, descrever as relações entre os Guarani-Mbya e os ratos no contexto da Terra Indígena Jaraguá, situada no noroeste da cidade de São Paulo. Busco compreender, sobretudo, como os Guarani percebem e relacionam-se com essas “espécies companheiras”, mesmo que sua companhia seja, algumas vezes, incômoda e indesejada. Ao analisar categorias cosmológicas Guarani associadas aos ratos – como sujo, feio e podre – argumento que os discursos de meus interlocutores sobre as relações entre roedores e humanos podem ser lidos como uma profunda crítica Guarani ao potencial predatório e destrutivo do modo de vida dos brancos.
Ao passo da hipoterapia:
Authors: Costa Ítalo Cassimiro
Published: April 2022

Pretende-se, no presente artigo, refletir sobre as múltiplas formas de medicalização da vida que ressurgem nos contextos contemporâneos. A partir do trabalho etnográfico em centros de hipoterapia (terapia assistida por cavalo) de Minas Gerais, circunscrevo a relação de coexistência entre terapeutas, cavalos, praticantes de hipoterapia, trabalhadores, familiares, equipamentos de montaria e tantos outros envolvidos na busca pela manutenção da saúde por meio de uma técnica que vem ganhando contornos diferentes em cada contexto. A partir desse chão etnográfico, a narrativa que compõe este texto se encarrega de duas tarefas: primeiro, refletir sobre a vinculação intra e interespecífica que têm como finalidade a manutenção da saúde humana por meio da hipoterapia; em segundo lugar, deslocar o entendimento sobre a medicalização da vida para o âmbito dos estudos sociais da ciência. O artigo leva em conta a multiplicidade inevitável dos fenômenos que compõem as tramas da técnica e do corpo, as práticas de tratamento e cura, assim como as categorizações médicas, as quais ao modificarem-se transformam toda uma rede de agentes que buscam a preservação da saúde por meio das terapias complementares. Afinal, como justificar os benefícios que a relação com os cavalos traz para a saúde senão pelas conexões com a linguagem, pelas hipóteses científicas ou pelas políticas públicas? Argumenta-se, portanto, que perspectivas universalistas sobre as ciências do corpo tendem a abstrair a compreensão dos fenômenos e suprimir a produção das evidências ciêntíficas a uma especialidade ou outra, enquanto a hipoterapia se multiplica interdisciplinarmente em formas localizadas de operação do conhecimento científico.
Comum terrano
Authors: Chaparro Yan Leite , Mesa Leandro de Alencar Lamberti
Published: April 2022

O ensaio que segue é uma provocação à imagem do humano a partir da especulação do personagem radical e emergente do Terrano, quando um outro contesta e reflete sobre as ações já normalizada de outro. Escolhemos o personagem do Terrano para iniciar uma discussão teórica ainda pouco ouvida, tanto no Mato Grosso do Sul, quanto no Brasil: a era do Antropoceno, fenômeno que coloca o hoje e o amanhã como uma grande dúvida para os humanos e para muitos não humanos. Início que busca caminhos solidários entre humanos e não humanos, e também, para a produção real do Terrano.
Políticas públicas dos EUA e da China para a pandemia: tensões geopolíticas, competição tecnológica e modelos de desenvolvimento
Authors: Poty Italo Barreto , Aguiar Caroline Boletta de O.
Published: April 2022

Este artigo tem como objetivo analisar as respostas dos Estados Unidos e da China em termos de políticas públicas de combate à pandemia da COVID-19, com ênfase no contexto atual de acirramento das tensões geopolíticas, na competição tecnológica e nos modelos de desenvolvimento de ambos os países. Considerando a importância da internet na contemporaneidade para áreas essenciais como economia, política, segurança e defesa, daremos destaque à corrida pela liderança no desenvolvimento das redes 5G. A questão principal que propomos é: qual foi o papel da pandemia na disputa geopolítica entre China e Estados Unidos, considerando sua dimensão tecnológica? A metodologia de pesquisa adotada é a análise qualitativa de documentos oficiais e bibliografia especializada sobre o tema. Nossa hipótese é que a pandemia pode ter conferido vantagem à China na corrida pela liderança no 5G, considerando o maior foco dado pelo governo chinês aos investimentos nessa tecnologia e sua importância no combate à pandemia no país asiático, em que a internet foi essencial para o controle do isolamento social como forma de conter a disseminação do vírus. Os Estados Unidos, por sua vez, concentraram seus esforços no setor de biotecnologia para combater a pandemia.
Estados Unidos e a política de controle de fronteiras: práticas de militarização e mecanismos de vigilância com o México no pós-11 de setembro
Authors: Brancoli Fernando Luz , Gomes Simone da Silve Ribeiro
Published: April 2022

A chegada de Donald Trump à presidência dos EUA reanimou debates sobre a gestão das fronteiras do país, principalmente com o México. A partir de um estudo qualitativo, com uma revisão bibliográfica, o artigo demonstra que, apesar da mudança de tom, os governos anteriores de George W. Bush e de Barack Obama já imprimiam um caráter de contínua militarização deste espaço, com a constituição discursiva de "ameaças externas" e o emprego de dispositivos materiais translados dos conflitos armados. O artigo faz uma análise qualitativa da fronteira EUA-Mèxico para materializar tais pontos e questões.