bluuebunny/crossref_metadata_2025 huggingface dataset:
Rancang Bangun Antena Mikrostrip Path Rectangular pada Frekuensi 900 MHz untuk Aplikasi GSM
Authors: Setiawan Muhammad Imam , Endri Jon , Sarjana Sarjana
Published: October 2021

INTISARIAntena adalah perangkat yang sangat penting dalam teknologi penyampaiian informasi. Oleh karena itu, pada zaman sekarang ini Beragam jenis antena telah banyak dikembangkan, salah satunya adalah antenna mikrostrip. antenna mikrostrip ini memiliki banyak keunggulan sehingga sering digunakan dalam berbagai perangkat seluler. Semakin bertambahnya pengguna perangkat seluler membuat banyaknya penggunaan spektrum frekuensi untuk komunikasi seluler. Salah satu frekuensi yang banyak digunakan adalah frekuensi 900 MHz untuk sistem GSM. Dalam jurnal ini menyajikan mengenai perancangan antenna mikrostrip yang dapat digunakan dalam Sistem GSM.. Antena ini dibuat dengan bahan substrat epoxy dengan Konstanta dielektrik (εr)=4.4 dan ketebalan 1.6 mm serta menggunakan saluran pencatuan feed line. Penambahan element menjadi antena array memiliki tujuan untuk meningkatkan nilai gain antena agar dapat meningkatkan daya yang diterima oleh pengguna jaringan dan dapat menambah jarak jangkauan dari BTS menuju perangkat seluler. Dari hasil pengukuran langsung dilaboratorium, didapatkan karakteristik dari antena yang dibuat memiliki besar return loss -11.077 dB, VSWR 1.775, gain 6.8 dBi. Kata kunci— Antena mikrostrip, Gain, Return loss, VSWR, pola radiasi, Linear array ABSTRACTAntennas are very important devices in information delivery technology. Therefore, in this day and age various types of antennas have been developed, one of which is a microstrip antenna. This microstrip antenna has many advantages so it is often used in various cellular devices. The increasing number of mobile device users makes a lot of use of the frequency spectrum for cellular communication. One frequency that is widely used is the 900 MHz frequency for GSM systems. In this journal, it presents the design of microstrip antennas that can be used in GSM systems. This antenna is made with epoxy substrate material with dielectric constant (εr) = 4.4 and thickness of 1.6 mm and using feed line rationing channels. Adding an element to an array antenna has the purpose of increasing the antenna gain value so that it can increase the power received by network users and can increase the range of distance from the BTS to the mobile device. From the results of direct measurements in the laboratory, it was found that the characteristics of the antenna made had a large return loss of -11.077 dB, VSWR 1.775, gain 6.8 dBi.Keywords : microstrip antenna, Gain, Return Loss, Radiation Pattern, Polarization
Sistem Pendukung Keputusan Pemilihan Rental Mobil Dengan Metode Simple Additive Weighting (SAW)
Authors: Anief Fauzan Rozi Imanuel Hofni Sipahelut,
Published: October 2021

Kota Yogyakarta adalah termasuk kota yang mempunyai kebudayaan serta tempat wisata yang beraneka ragam, hal tersebut menyebabkan banyak wisatawan yang ingin berkunjung dan berwisata di Yogyakarta, akan tetapi berdasrkan survey banyak dari wisatawan tersebut tidak menggunakan kendaraan khsusunya mobil pribadi ketika mengunjungi tempat objek wisata tersebut, sehingga diharuskan untuk me-rental mobil selama berada di Yogyakarta. Keterbatasaan wisatawan dalam melakukukan akses informasi tentang spesifikasi mobil dan rental mobil yang sesuai dengan kebutuhan menyebabkan masalah tersendiri untuk para wisatawan.Oleh karena itu dibutuhkan sebuah sistem pendukung keputusan untuk mendukung dan mempermudah wisatawan memilih suatu mobil dan tempat rental. Banyak metode sistem pendukung keputusan yang sering digunakan, antara lain metode Simple Additive Weighting (SAW). hasil akhir penelitian ini adalah sebuah sistem pendukung keputusan pemilihan mobil rental terbaik dengan hasil pengujian validasi sebesar 82%.Kata kunci: Wisatawan, Mobil, Rental, Simple Additive Weighting (SAW)
Interdisciplinary joint clinical activity between Diabetologist and Orthopedic for the treatment of diabetic foot in the North West Tuscany
Authors: Casadidio, I.
Published: October 2021

The diabetic foot can be treated only if you know how to work as a team and the diabetologist, the natural referent of the clinical case, has to create a multiprofessional/multidisciplinary team that can manage the patient to prevent injuries and treat them if they show up. The creation of structured diagnostic-therapeutic paths guarantees a better coordination of the professional figures involved, optimizes the management of the direct and indirect resources required to manage such a clinically challenging complication. After many years of activity we have built a solid integration between diabetologist and orthopedic, between hospital and territory and we have simplified a complex path. The fulcrum of this activity is the joint orthopaedic clinic that guarantees the correct care of the patient and allows the professional growth of the whole team. KEY WORDS diabetic foot; integrated management; PDTA; team.
Fault Seal Analysis Menggunakan Metode Shale Gouge Ratio Pada Reservoir Batugamping Formasi Kais Lapangan “AR”
Authors: Rahman Arief , Utomo Warto , Panca Kusuma Bangbang , Almuqtadir Thariq
Published: October 2021

Fault Seal Analysis (FSA) adalah analisis untuk menentukan patahan/sesar bersifat sealing (tersekat) atau leaking (bocor). Salah satu metode untuk menentukan FSA adalah Shale Gouge Ratio (SGR) yang pertama kali dikemukaan oleh Yielding (1997).  Tujuan penelitian ini menentukan sealing atau leaking patahan pada batugamping Formasi Kais lapangan “AR” Cekungan Bintuni, Papua Barat, dan analisis pengaruh ketebalan lapisan (∆z) dan volume shale (Vsh) dalam rumus SGR. Data penelitian yang digunakan yaitu satu sumur minyak (sumur AR-3), penampang lapisan formasi, dan throw dari 3 (tiga) patahan (F1, F2, F3) di sekitar sumur tersebut. Metode penelitian adalah SGR untuk menentukan sealing atau leaking, sedangkan analisis pengaruh ketebalan lapisan (∆z) dan volume shale (Vsh) dalam rumus SGR dilihat berdasarkan R square dari grafik antara ∆z dengan SGR, dan grafik antara Vsh dengan SGR, untuk tiga patahan tersebut. Hasil penelitiannya yaitu; dari tujuh lapisan di dalam satu tubuh formasi Kais, didapatkan berbagai macam sifat leaking, sealing / leaking, dan sealing, di tiga patahan (F1, F2, F3). Namun, SGR Formasi Kais dengan tebal 270 ft dan Vsh 21%, maka nilai SGR selalu lebih dari 100% yang berarti sealing. Hasil nilai R square grafik Δz terhadap SGR = 0,743 jauh lebih tinggi dibanding Vsh terhadap SGR = 0,036. Kesimpulannya; nilai total ketebalan shale (Δz*Vsh) harus lebih kecil sama dengan dengan nilai throw fault-nya, atau dapat ditulis Δz*Vsh ≤ Throw Fault, jika tidak, maka nilai SGR akan selalu melebihi 100%. Rumus SGR jauh lebih dipengaruhi oleh ketebalan lapisan (Δz), dibanding dengan Volume Shale (Vsh).
Pengaruh Harga, Promosi dan Kualitas Pelayanan Terhadap Loyalitas Pelanggan Melalui Kepuasan Pelanggan Sebagai Variabel Intervening
Authors: Kuswandi Dadi , Nuryanto Guyub
Published: October 2021

Saat ini teknologi yang semakin berkembang di seluruh dunia yang tidak bisa di pungkiri lagi. Dengan adanya teknologi yang semakin berkembang pesat akan dapat membantu mempermudah masyarakat dalam melakukan aktivitas sehari-hari karena kemudahan dalam mengakses teknologi. Tujuan dari penelitian ini adalah untuk mengetahui dan menganalisis apakah variabel Harga, Promosi dan Kualitas Pelayanan berpengaruh signifikan terhadap Loyalitas Pelanggan melalui Kepuasan Pelanggan sebagai variabel interveningnya. Studi kasus pada pengguna Traveloka di Kelapa Dua, Tangerang. Metodologi yang dipergunakan dalam penelitian ini adalah pengumpulan data melalui penyebaran kuesioner secara online dan menggunakan teknik purposive sampling pada 135 responden yang telah menggunakan aplikasi Traveloka di Kelapa Dua, Tangerang. Pengujian ini dilakukan dengan program SPSS versi 20 dan AMOS versi 23. Pada tahap analisis dilakukan uji validitas, uji reliabilitas, dan Structural Equation Model (SEM). Hasil penelitian menunjukkan variabel harga, promosi dan kualitas pelayanan memiliki pengaruh yang positif terhadap kepuasan pengguna Traveloka di Kelapa Dua, Tangerang, variabel promosi memiliki pengaruh yang positif terhadap loyalitas pelanggan dan kepuasan pelanggan berpengaruh positif terhadap loyalitas pelanggan, sedangkan harga dan kualitas pelayanan tidak berpengaruh positif terhadap Loyalitas Pengguna Traveloka di Kelapa Dua, Tangerang.
ВЛИЯНИЕ КОМПЛЕКСОНАТОВ МИКРОЭЛЕМЕНТОВ НА ФИЗИОЛОГИЧЕСКИЕ ПОКАЗАТЕЛИ КРОВИ ИССЛЕДУЕМЫХ ЖИВОТНЫХ
Authors: Арсанукаев Д.Л. , Зайналабдиева Х.М. , Виситаева М.З. , Сайдулаева П.Ю.
Published: October 2021

Морфологический и биохимический составы крови здорового организма имеют постоянный гомеостаз. Химический состав крови складывается из белков, липидов, углеводов, гормонов, витаминов, минеральных элементов и различных терминальных продуктов. В цитологическом составе крови 45 – 50% занимают эритроциты, лейкоциты и тромбоциты, а плазма ̶ 50 – 55%. В физиологически здоровом организме, несмотря на постоянное поступление и экскрецию из него различных веществ, сохраняется гомеостатическое равновесие. Интенсивность метаболических процессов зависит от обеспеченности организма пластическим материалом [2]. Применение в составе рациона козлят хелатированных форм микроэлементов обеспечило оптимизацию цитологического состава крови и биохимического статуса, что конвергируется на конституциональном становлении генома особей опытной группы.
Realidades y retos en el uso de las TIC en educación, por la emergencia sanitaria provocada por el COVID-19
Authors: Martínez Márquez Marco Antonio
Published: October 2021

The paper first addresses the educational policies dictated at the international and national levels to deal with the health emergency caused by COVID-19. The main objective of these policies has been not to stop the teaching-learning processes, moving from face-to-face and blended modalities to an online modality, trying not to neglect aspects such as educational quality. Afterwards, those dictated and implemented by the University Network of the University of Guadalajara (U. de G.) are analyzed. Then, the reality faced by the professors of the Centro Universitario del Norte (CUNorte) to continue their teaching work is described. Finally, the challenges in the short, medium and long term, related to the use of information and communication technologies (ICT), such as the lack of training in digital platforms and tools, computer equipment for work, obsolescence of the same and problems of Internet connectivity, among others.
On the Hermeneutics of Reading Historical Texts in the Mathematics Classroom
Authors: Fossa John A.
Published: October 2021

A hermeneutical substructure for the reading of historical texts in the mathematics classroom is described. It is organized according to the four transcendentals of unity, truth, beauty and goodness, each of which is considered internally –with respect to the text itself – and externally – with respect to both its relations to mathematical thought in general and other cultural manifestations. Lead questions are provided for each category as are also details regarding various ways in which the student’s interactions with the text can be organized in order to provide the student with a rich learning experience. Some attention is also given to questions relating to implementation.
Penerapan Model Pembelajaran Kolaboratif Untuk Peningkatan Hasil Belajar Muatan Pelajaran PPKn Dan Sikap Sosial Siswa Kelas II SD Negeri 1 Tumbu
Authors: Sukadi Ni Ketut
Published: October 2021

This study aims to improve learning outcomes and social attitudes of second grade students in the odd semester of the 2017/2018 academic year through the application of a collaborative learning model in the content of Civics lessons. This research was conducted in two learning cycles. The learning model used in this study is a collaborative learning model. The object of research is social attitudes and student learning outcomes. To measure students' social attitudes, observational guidelines were used. To measure student learning outcomes used test learning outcomes. The data analysis used in this research is descriptive analysis. The results of data analysis showed that: 1) The application of the collaborative learning model can improve the learning outcomes of class II SD Negeri 1 Tumbu. There was an increase in student learning outcomes of Civics from the first cycle of 73.91 to the second cycle of 86.96 this indicates an increase in learning outcomes of Civics learning content of 17.65%. 2) The application of the collaborative learning model can improve the social attitudes of the second grade students of SD Negeri 1 Tumbu. The average value of students' social attitudes increased from 66.09 in the first cycle with the medium category to 80.96 in the second cycle with the high category. This indicates an increase in students' social attitudes by 22.50%. Learning outcomes in learning will be better if before carrying out the learning process prepare the required learning tools carefully and planned in advance in order to achieve the desired learning objectives.
LEGAL REGULATIONS OF ART IN FRENCH LEGISLATION
Authors: Dyuka A.
Published: October 2021

France is one of the rare countries which implements the fundamental mechanism for improving legislation on Bioethics. Since 1994, every five years bioethics laws are revised in order to follow medical advances (medicine), authorize new practices and impose restrictions, expressly in order to guarantee the fundamental principles laid down by the Law N94-653 of 29 July 1994 (dignity, primacy of the human person, inviolability, integrity and non-ownership of the human body and its elements). Medically assisted procreation (ART) is one of the fields under regular review. This article outlines the French law on ART and surrogacy. In spite of the fact that surrogacy is prohibited in France, the infertile couples seek surrogacy outside of the country. Over the last few years, under pressure from the ECHR and expressly to protect child interests, the French relaxed their position in order to recognize the affiliation of children born from surrogacy. The current revision of bioethical laws aims, among other things, to open up access to ART for all women (including single women and lesbian couples) and to simplify the recognition in France of the affiliation of children born by surrogacy abroad.
PROGNOSTICATION LABOR DYSTOCIA AND CESAREAN SECTION
Authors: Grishchenko O.V. , Mamedova S.
Published: October 2021

The article presents the results of the analysis of clinical and anamnestic indicators to create a model for predicting the development of labor dystocia that caused Caesarean section. The most significant prognostic factors included in the prognostic model were fetus-pelvic imbalances, diabetes mellitus, a burdened gynecological history and cardiovascular diseases in the nulliparous women of late reproductive age. Assessment of the totality of risk factors made it possible to achieve an accurate prognosis in 88.6% of cases with a sensitivity of 40.4%, specificity - 92.1%.
MODERN GOING NEAR PROPHYLAXIS OF OBSTETRIC TRAUMATISM AND ITS CONSEQUENCES
Authors: Zhabchenko I.A .
Published: October 2021

The article provides up-to-date data on the frequency, risk factors and causes of obstetric injuries of the soft tissues of the birth canal. The directions of preventive measures regarding the prevention of both the injuries themselves and their immediate and delayed complications are presented. As a preventative measure, the advantages of two-stage rehabilitation of the birth canal with the help of the selective probiotic «Vagilak» are presented, which allows you to quickly eliminate the clinical signs of vaginal inflammation and prevents relapse of the process. As an aid to the prevention of obstetric injuries and the treatment of its consequences, the possibilities and advantages of “Vagilak” moisturizing gel and soap for intimate hygiene are presented. The article defines the profile of patients who show the use of these drugs before childbirth, in childbirth and in the postpartum period.
MAGNETIC RESONANCE IMAGING OF PELVIC FLOOR DYSFUNCTION, REVIEW
Authors: Orazov M. R. , Toktar L.R. , Rybina A.N. , Gevorgian D.A. , Dostieva Sh.M. , Lologaeva M.S. , Karimova G.A.
Published: October 2021

Pelvic floor dysfunction is an important medical and social problem in the female population. The impact of pelvic floor disorders (PFD) is likely to grow as the prevalence of these disorders increases with an aging population. Pregnancy and delivery are considered major risk factors in the development of POP and stress urinary incontinence. Pelvic floor dysfunction may involve pelvic organ prolapse and/or pelvic floor relaxation. Organ prolapse can include any combination of the following: urethra (urethrocele), bladder (cystocele), or both (cystourethrocele), vaginal vault and cervix (vaginal vault prolapse), uterus (uterineprolapse), rectum (rectocele), sigmoid colon (sigmoidocele),and small bowel (enterocele).Given the paucity of understanding of PFD pathophysiology ,multicompartmental pathology, the high rate of recurrence and repeat surgery imaging plays a major role in its clinical management.The magnetic resonance imaging (MRI) allows noninvasive, radiation-free, rapid, high-resolution evaluation the multicompartment defects in one examination.Findings reported at MR imaging of the pelvic floor are valuable for selecting candidates for surgical treatment and for indicating the most appropriate surgical approach.
ВРТ В УСЛОВИЯХ ПАНДЕМИИ: ОРГАНИЗАЦИЯ ДЕЯТЕЛЬНОСТИ ЛАБОРАТОРИЙ ВРТ 04.05.2020. Международная встреча экспертов
Authors: Локшин В.Н. , Корсак В.С. , Фельдберг Д. , Смирнова А.А. , Колода Ю.А , Ершова А. , Шурыгина О.В.
Published: October 2021

ВРТ В УСЛОВИЯХ ПАНДЕМИИ: ОРГАНИЗАЦИЯ ДЕЯТЕЛЬНОСТИ ЛАБОРАТОРИЙ ВРТ 04.05.2020. Международная встреча экспертов
ASSISTED REPRODUCTIVE TECHNOLOGIES IN KAZAKHSTAN IN 2017: SUMMARY REPORT ON EFFICIENCY AND AVAILABILITY
Authors: Lokshin V.N. , Omar M.D. , Karibaeva Sh.K. , Dzhusubalieva T.M. , Baikoshkarova S.B. , Akhmetova A.A. , Pokotilo L.I. , Dyusembinov K.S. , Tararaka S.S. , Tararaka N.S.
Published: October 2021

The article contains a descriptive analysis to study the characteristics and outcomes of treatment with various methods of assisted reproductive technologies (ART). The report includes data on ART cycles registered by the Kazakhstan Association for Reproductive Medicine for the period from January 1 to December 31, 2017. A total of 10,523 ART treatment cycles and 2,037 newborns were registered in 2017. The accessibility of ART treatment was 583 cycles per million population. The Instruction of the President of the Republic of Kazakhstan given in the Message of September 1, 2020 is an important step to improve the reproductive potential of the country.
EARLY MARKERS OF DIAGNOSIS FETAL GROWTH RESTRICTION SYNDROME
Authors: Ikhtiyarova G.A. , Aslonova M.J. , Dustova N.K.
Published: October 2021

The article presents the effectiveness of Dopplerometry for assessing blood flow in large vessels, including the umbilical, uterine artery and middle cerebral artery, 90 women were examined in the second trimester, and 45 women showed signs of placental insufficiency, such as fetal growth restriction syndrome at 28-34 weeks. The results of the study showed that 23 (51.1%) women had signs of subcompensated insufficiency of uteroplacental blood flow, and 11 (24.4%) women showed signs of fetal-placental blood flow. The study of the uteroplacental-fetal blood flow allows early detection of early signs of impairment in the fetoplacental system and its timely correction.
ВЛИЯНИЕ ТЕРРИТОРИАЛЬНОГО ФАКТОРА НА МОРФОФУНКЦИОНАЛЬНЫЕ ХАРАКТЕРИСТИКИ СПЕРМАТОЗОИДОВ МУЖЧИН РЕПРОДУКТИВНОГО ВОЗРАСТА ПО ДАННЫМ КЛИНИКИ «МАТЬ И ДИТЯ»
Authors: Тугушев М.Т. , Мякишева Ю.В. , Щелочков А.М. , Федосейкина И.В. , Сказкина О.Я. , Шурыгина О.В.
Published: October 2021

Состояние репродуктивного здоровья населения является важнейшей составляющей социально-демографического развития страны. Актуальной проблемой является определение фертильности мужчин с целью выявления у них заболеваний половой системы и возможности продолжения рода. Мужское бесплодие – деликатная проблема, охотно отрицаемая и не признаваемая многими мужчинами. В связи с этим распространенность репродуктивной несостоятельности мужского населения сильно превышает официальные данные (данные ВОЗ), согласно которым около 25% семейных пар не достигают беременности в течение года, причем 40% из них по причине мужского бесплодия [3]. Как известно, мужское бесплодие проявляется отсутствием зачатия при регулярной половой жизни со здоровой женщиной детородного возраста в течение 1,5-2 лет без применения контрацептивов [2]. Учёными доказано, что на развитие патологии влияет возраст человека, наличие инфекционных заболеваний и многие другие факторы. Определение частоты встречаемости бесплодия у мужчин в районах Самарской области позволит выявить зависимость характеристик эякулята от экологической обстановки.
LAPAROSCOPIC PECTOPEXY. IRM EHPERIENCE
Authors: Dzhakupov D.V. , Kudaibergenov T.K. , Barmanasheva Z.E. , Karabekov N.B.
Published: October 2021

A study carried out at the Institute of Reproductive Medicine proved that laparoscopic pectopexy is a reliable, safe and convenient method for treating pelvic organ prolapse and can be a good alternative to sacrocolpopexy.
PREGNANCY AFTER IVF IN A PATIENT WITH SHERESHEVSKY-TURNER SYNDROME (clinical case)
Authors: Sarmuldayeva Sh.K.
Published: October 2021

Shereshevsky-Turner Syndrome (SJT) is caused by full or partial X-monosomy, presented in all or part of the cells of the body. For Shereshevsky-Turner syndrome, pronounced hormonal disorders are characteristic - these are primary ovarian, somatotropic, thyrotropic insufficiency, as well as defects of the cardiovascular and urinary systems. With the advent of ART, pregnancy has become more accessible for this category of patients, most often with a donor egg. In the available literature, it was not possible to find the exact information on the selection of progestogen support, duration of appointment, and term of withdrawal; therefore, the clinical case is presented below. In this case, we left high maintenance doses of progesterone, not only due to the use of ART, but also due to concomitant extragenital pathology, which leads to a decrease in all functions of the placenta, including endocrine.
SYNDROME OF HYPERSTIMULATED OVARIES. EXPERIENCE IRM.
Authors: Dzhakupov D.V. , Kudaibergenov T.K. , Sultanova J.U. , Barmanasheva Z.E. , Zholdasov R.A.
Published: October 2021

The article presents the experience of the gynecological department of the Institute of Reproductive Medicine in the conservative treatment of hyperstimulated ovary syndrome in women who underwent ovulation stimulation in the IVF center.
OVARIAN ENDOMETRIOSIS: THE MODERN POSSIBILITIES OF RELAPSE PREDICTION
Authors: Orazov M.R. , Abitova M.Z. , Khamoshina M.B. , Volkova S.V. , Aryutin D.G. , Shustova V.B.
Published: October 2021

The article summarizes the current understanding of risk factors and mechanisms of ovarian endometriosis relapses,

This article summarizes the current understanding of risk factors for relapse, mechanisms of recurrence of endometrioid ovarian cysts, as well as the potential for their prediction using genetic and molecular-biological predictors.
INTERFERON STATUS OF ENDOMETRY IN PATIENTS WITH MISCARRIAGE AND “THIN ENDOMETRY” SYNDROME
Authors: Mamedalieva N.M. , Kurmanova A.M. , Anartaeva G.Zh. , Moshkalova G.
Published: October 2021

The article presents the results of examination of 21 patients with miscarriage and “thin endometry” syndrome compared with 20 patients without reproductive losses and the presence of normal endometrial thickness. Interferon gamma intracellular production by cytotoxic endometrial lymphocytes was investigated by flow cytofluorometry. Based on the study, it was found that in patients with miscarriage and “thin endometry” syndrome, the interferon gamma intracellular production by cytotoxic CD8+ lymphocytes was sharply suppressed by almost 36 times, by CD56+ lymphocytes - by 13 times, by CD16+ lymphocytes - by 4.5 times.
SEMEN FERTILITY INDICATORS OF YOUNG MEN OF THE CITY OF ALMATY WITH COMPLAINTS ABOUT UNFERTILIZED MARRIAGE
Authors: Zadubenko D.V. , Lokshin V.N. , Arepiev V.E. , Kim I.M. , Pak M.I. , Aytasheva Z.G.
Published: October 2021

The article presents the results of studies of the ejaculate of 331 young men permanently residing in the city of Almaty and having complaints of infertile marriage for at least 12 months after the termination of all types of contraception.
UTEROTONIC DRUGS IN THE PREVENTION OF POSTPARTUM HEMORRHAGES
Authors: Khamidullina Z.G. , Myrzabekova A.Zh. , Syzdykova A.Zh.
Published: October 2021

In the world practice, hemorrhages in obstetrics take leading positions within the causes of maternal morbidity and mortal ity. 800 women die every day due to childbirth complications under the data of the World Health Organization. The majority of maternal deaths occur during the perinatal period, usually within 24 hours postpartum. It is possible to prevent most of them. Lack of adequate pre-conceptional training, uncompensated extragenital diseases increase the percentage of pathological births. Consequently, practicing obstetricians-gynecologists have to face such childbirth complications as postpartum hemorrhage with increasing frequency. Uterine atonia is the main cause of postpartum hemorrhages. Uterotonic drugs administration enables to re- duce the risk of postpartum atonic hemorrhages. Particular attention should be paid to postpartum hemorrhage prevention, i.e. the use of uterotonic drugs as an integral part of the active management during the third period in natural labor and caesarean section.
MODERN TREATMENTS FOR PCOS (LITERATURE REVIEW)
Authors: Korkan A.I. , Turekhanova A.D. , Tyugay Y.L.
Published: October 2021

According to world statistics, polycystic ovary syndrome (PCOS) is one of the most common forms of endocrinopathy in women of mainly reproductive age. PCOS can cause metabolic dysfunction, ovulatory infertility, endometrial cancer, pre- mature birth, perinatal mortality, and other serious consequences. The article discusses various methods of conservative and surgical treatment of PCOS. The main focus is on conservative treatment of infertility caused by PCOS.
MITOCHONDRIAL REPLACEMENT THERAPY: FUTURE OR PRESENT?
Authors: Chalova L.R. , Lokshin V.N.
Published: October 2021

In this review, conducted according to world literature, we sought to determine the role of mitochondrial DNA (mtDNA) in the formation of mitochondrial diseases. To determine the availability of treatment methods for hereditary diseases, in particular those associated with mitochondrial diseases, and to assess the role of mitochondrial replacement therapy (MRT) in assisted reproductive technologies.
The scientific articles corresponding to the chosen goal are published on MEDLINE, EMBASE, in the Cochrane Library, PubMed, and other information sources.
The search strategy combined the following search terms “mitochondrial diseases,” “mitochondrial replacement therapy,” “three-parent baby,” “ART,” “genetic engineering”.
Особенности течения беременности / родов / послеродового периода у женщин с положительными результатами на COVID-19
Authors: Исенова С.Ш. , Бодыков Г.Ж. , Шукирбаева А.С. , Кубесова М.О. , Давранова М.У. , Молдабек Д.М. , Аймагамбетова А.С. , Семенякина О.А.
Published: October 2021

Проведен ретроспективный анализ по данным архивного материала Центра перинатологии и детской кардиохирургии г. Алматы за 2020 г.Анализ проводился у беременных женщин с COVID-19, всего исследовано150 историй. Особенности течения беременности и родов были оценены путем изучения данных лабораторно-диагностических методов исследования, клинических симптомов, рентгенологических, УЗИ, допплерометрических исследований. Проведенное исследование освещают особенности течения беременности, родов и послеродового периода у женщин, инфицированных COVID- 19.
Дисморфизмы ооцитов в программах ВРТ. обзор литературы
Authors: Карибаева Г.М. , Тевкин С.И. , Джусубалиева Т.М. , Шишиморова М.С.
Published: October 2021

В обзоре представлены данные литературы и анализ результатов исследований в области вспомогательных репродуктивных технологий, посвященных изучению морфологических особенностей и аномалий (дисморфизмов)ооцитов человека. Описаны виды  интрацитоплазматических аномалий, встречающихся в клинической практике экс-тракорпорального оплодотворения, их влияние на оплодотворение, дробление, частоту имплантации, частоту клинической беременности, а также их возможное использование в качестве биомаркеров в прогнозировании качества эмбрионов и бластоцист, и дальнейшего имплантационного потенциала.
Хронический эндометрит у пациенток с повторными неудачами имплантации: эпидемиология, этиология, патогенез и преодоление бесплодия
Authors: Оразов М.Р. , Михалёва Л.М. , Силантьева Е.С. , Орехов Р.Е.
Published: October 2021

Данные последних лет указывают на то, что качество эндометрия играет гораздо более важную роль в успешной имплантации и наступлении клинической беременности, чем многие другие признанные факторы. Хронический эндометрит (ХЭ) ассоциирован с отрицательными репродуктивными исходами, которые включают повторные неудачи имплантации. Streptococcusspp., Escherichiacoli, Enterococcusfaecalis, Klebsiellapneumoniae, Staphylococcusspp., Corynebacterium и Mycoplasma / Ureaplasmaspp в настоящее время считаются основными возбудителями ХЭ. Это заболевание нарушает архитектонику эндометрия на разных уровнях: прежде всего, ХЭ способствует изменениям в популяции иммунокомпетентных клеток и, следовательно, способствует нарушению локального иммунного ответа в эндометрии в момент имплантации. Лечение ХЭ антибиотиками улучшает частоту имплантации и снижает частоту абортов, хотя хорошо спланированные проспективные исследования, подтверждающие этот вывод, отсутствуют.Учитывая недостаточную эффективность антибиотикотерапии ХЭ, особенно в случаях резистентности возбудителей, либо в случае вирусного хронического эндометрита, необходимо разработать схемы с дополнительным применением препаратов, влияющих на другие этиопатогенетические пути развития и поддержания ХЭ. Примером такого лечения может быть цитокинотерапия, требующая дальнейшего изучения в отношении эффективности и безопасности в терапии ХЭ.
Плазмолифтинг как метод выбора при лечении атрофического вагинита у женщин в состоянии климактерического периода
Authors: Алимбаева С.С. , Манабаева Г.К.
Published: October 2021

Данное исследование, проведенное в гинекологическом центре «Жамиля» (г. Семей, Казахстан), показывает эффект применения метода плазмолифтинга у женщин в состоянии климактерического периода, имеющих симптомы атрофического вагинита.
Влияние акушерского геля на процесс и продолжительность родов
Authors: Исенова С.Ш. , Бодыков Г.Ж. , Алтаева А.А. , Исина Г.М.
Published: October 2021

В статье рассмотрена проблемы слабой родовой деятельности, акушерского травматизма, увеличение числа оперативных вмешательств. Проведено исследование эффективности и безопасности акушерского геля Dianatal при его применении в родах.
Влияние переносов размороженных бластоцист, экспандированных на пятые или шестые сутки на эффективность программ ВРТ
Authors: Полумискова А.О. , Тевкин С.И. , Джусубалиева Т.М. , Шишиморова М.С.
Published: October 2021

Повышение эффективности программ вспомогательных репродуктивных технологий (ВРТ) невозможно без совершенствования и улучшения условий культивирования эмбрионов с последующим переносом или криоконсервацией экспандированных бластоцист достигших нужной стадии к пятым или шестым суткам развития.Цель исследования - оценка влияния дня культивирования бластоцист человека, достигших необходимой стадии экспандирования на эффективность программ ВРТ, частоту наступления клинической беременности (ЧКБ), частоту ранних потерь и частоту живорождения в криопротоколах при проведении программ ВРТ. Проанализированы данные программ переноса размороженных эмбрионов (ПРЭ) экспандированных на 5-е, группа А (N=2275) или 6-е сутки, группа Б (N=170). Частота наступления беременности (ЧНБ) в исследуемых группах составила 50,8 и 46,5%, соответственно. Не наблюдалось статистически достоверных различий в показателях частота наступления клинической беременности (ЧКБ) 37,4 и 37,0% и частота ранних потерь беременности 26,0 и 21,5% у пациенток обеих групп, соответственно. Основной показатель эффективности работы клиники ЭКО – частота живорождения (Take-HomeBabyRate) в криопротоколах с переносами экспандированных бластоцист на пятые (группа А) или шестые сутки (группа Б) составил 36,5 и 35,2%, соответственно (разница не достоверна).В криопротоколах день экспансии бластоцист (5-е или 6-е сутки развития) статистически не влияет на ЧКБ, частоту ранних потерь беременности и частоту живорождения. В программах ПРЭ в первую очередь следует отдавать приоритет качеству бластоцист (отличное и хорошее) не зависимо от дня их криоконсервации.
How to Understand the End of Conflict? Addressing a Theoretical Context from Zartman’s Theory and a “Three-Dimensional” View
Authors: Cano-Holguín Nelson , Jiménez-Osorio Javier
Published: October 2021

Based on the assumption that each armed conflict has different origins, the end of the conflict corresponds to a cessation of hostile activities and the beginning of a peace process. However, recognizing when the parties immersed in a conflict have the will to negotiate is a complex issue to understand. In this sense, this article addresses Zartman’s theory of maturation to increase the understanding of the elements necessary for the parties to come together and resolve their conflicts. The novelty of this article is that it complements such a theory with a three-dimensional vision of the end of the conflict, that is, military, political and economic dimensions. Based on a bibliographic review, the main conclusion is linked to the possibility of providing the understanding of conflicts with some arguments through the theory of Zartman’s ripening; however, this still has limitations in the sense that such a moment of ripening does not guarantee that the conflict will be solved, nor does it offer a look at it before reaching that moment, but it is possible to observe it only after it passes, giving rise to new investigations that go deeper into those gaps.
Effectiveness of target signal migration compensation at compression filter output
Authors: Elagina K. A.
Published: October 2021

The paper describes a case study with the target moving at unknown radial velocity. Exemplified by the frequency modulation signal, the study presents the analysis of specific features of channel multiplexing for the target range migration compensator at the compression filter output within pulse burst periods. Channel multiplexing allows to reduces losses in case of long-term signal integration. The solution effectiveness is estimated and a method is proposed for compensator channel multiplexing ensuring protection against unwanted signal expansion.
Compensation of target signal migration in the multichannel matched filter
Authors: Elagina K. A.
Published: October 2021

The study proposes a method of target range signal compensation within different pulse burst periods during in-period matched filtering. The proposed method allows to reduce losses in case of long-term signal integration. This is especially important for signals highly sensitive to Doppler frequency shift. In terms of this parameter, a multichannel configuration of the compression filter is a probable solution for such signals. Based on the example of a signal with non-linear frequency modulation and the results of simulation modelling, we analyse the effectiveness of migration compensation and give recommendations on channel multiplexing for the compression filter with an integrated migration compensator.
Abrasive machining of high-alloy corrosion resistant steels by example of 12Kh18N10T
Authors: Romanenko A. M. , Shatko D. B. , Nepogozhev A. A. , Karavaev Ya. S.
Published: October 2021

The paper focuses on research into processing of high-alloy corrosion resistant steels by the method of centreless circular grinding. The physical and mechanical properties of such steels determine certain difficulties in their grinding as compared with other materials, which necessitates a thorough investigation of this issue. The paper presents experimental data on the dependence of machined surface roughness and hardness, as well as workpiece surface average temperature and microhardness, on the machining conditions and grinding wheel characteristics.
Manejo nutricional de café durante la etapa de almácigo.
Authors: Sadeghian Siavosh , Ospina-Penagos Carlos
Published: October 2021

Los resultados de una investigación para la etapa de almácigo demuestran que la respuesta de café a la aplicación de fertilizantes puede variar según el tipo de suelo, de allí la importancia de tener presente este aspecto al momento de definir los planes de manejo. En este Avance Técnico se presentan los resultados de una investigación en la que se evaluaron diferentes alternativas de fertilización y el uso de enmiendas durante la etapa de almácigo.
LAPOROSCOPIC PELVIC EXENTERATION FOR TREATMENT OF PRIMARY MULTIPLE CANCER. CASE REPORT
Authors: Gallyamov E. A. , Sanzharov A. E. , Agapov M. A. , Prokhorenko K. A. , Gololobov G. Yu. , Doronchyk D. N. , Daynego V. G.
Published: October 2021

This clinical case represents the experience of surgical treatment of a patient with multiple primary metachronous cancer: 1. Sigmoid cancer рТ4NxM0. Resection of sigmoid colon (16.12.2013). Three courses of adjuvant chemotherapy (XELOX). Recurrence (2015). Laparotomy, Colproctectomy with D3 paraaortic lymph dissection. Ileostomy (2015). One course of chemotherapy (XELOX). 2. Upper tract urothelial carcinoma (right ureter) pT2N0M0R0. Right nephroureterectomy with the resection of the bladder and right testicular cord, cystostomy (19.02.2015). Recurrence. Nephrostomy drainage of the left kidney. Adhesive disease. Rectovesical fistula. Taking into account the history and comorbid status of the patient, it was decided to perform laparoscopic supralevator pelvic exenteration, ureterectomy on the left. The duration of the operation was 280 minutes, intraoperative blood loss was 200 ml. The period of stay in intensive care is 24 hours, the patient was discharged on the 7th day after the operation, the resection margin was negative (R0). After 12 months, there is no data for the disease progressed.
ASSESSMENT OF EFFICIENCY OF COMBINED PHARMACOTHERAPY FOR IMPERATIVE AND MIXED URINARY DISORDERS IN WOMEN WITH THE INTERVAL SCALE
Authors: Danilov V. V. , Eliseeva E. V. , Danilov V. V. , Vol'nyh I. Yu. , Danilov V. V. , Sevryukov F. A.
Published: October 2021

Introduction.The search for effective drug combinations for treating continental disorders in women is still relevant. The interval scale for assessing lower urinary tract symptoms in women is a simple and convenient tool for monitoring pharmacotherapy. Objective: to evaluate the effectiveness of treatment of imperative and mixed urination disorders in women with alpha1-blockers in combination with nootropic drugs using an interval symptom rating scale.Materials and methods.Under observation there were 31 patients aged 40 to 73 years who applied to the Center “Urination Pathology” with mixed and imperative disorders of the continent and urinary incontinence. Conservative therapy was carried out with the appointment of alpha1-adrenoblockers, nootropic and metabolic drugs for an average of 5.8 months. The therapeutic effect is recorded using the interval symptom score scale.Results.After discontinuation of drugs, the overall score on the symptom rating scale decreased by 40.2%, imperative symptoms – by 29.5-50%, and quality of life increased by 19%. In the group of women aged 40-49, with comparable dynamics of symptoms with patients older than 50 years, therapy lasted less. The difference averaged 4.1 months and was associated with a higher frequency in the older age group of vascular, metabolic and neurological disorders that slow down the regulatory processes of urination recovery.Conclusion.Alpha1-blockers and nootropics are pathogenetically substantiated for the treatment of imperative disorders of urination and urinary incontinence. Evaluation using the interval scale reliably demonstrates their high clinical effectiveness, persistence of the therapeutic effect and the feasibility of application at the stage of selection for surgical treatment.
THE FUNCTIONAL STATE OF THE RENAL PARENCHYMA AFTER VARIOUS VIDEO ENDOSURGICAL METHODS OF TREATMENT OF PATIENTS WITH LARGE AND COMPLEX KIDNEY STONES
Authors: Pak Yu. G. , Yagudaev D. M. , Gallyamov E. A.
Published: October 2021

The work is based on the analysis of literature data devoted to the problem of preserving the functional state of the kidneys with various video endoscopic methods of surgical treatment of large and complex kidney stones. The purpose of the review is to highlight the likelihood of deterioration in the functional state of the kidneys in the postoperative period. A detailed analysis of postoperative outcomes in various minimally invasive methods of treatment of patients with large and complex kidney stones was carried out, with an overview of the possibility of using dynamic nephroscintigraphy as a method of objectively assessing the functional state of the kidneys.
MECKEL'S DIVERTICULITIS: A CASE FROM URGENT SURGERY. CLINICAL CASE
Authors: Studenova E. A.
Published: October 2021

Background. Meckel's diverticulum is an ileal diverticulum, formed as a result of incomplete reduction of the yolk duct, occurs on average in 2% of the population. Up to 25% of cases of this pathology are symptomatic or have complications (up to 16%), while more often it manifests in children under 2 years of age. Destructive diverticulitis is the least common complication of Meckel's diverticulum, requiring urgent surgical intervention.Clinical case. A 28-year-old patient with a clinical picture of acute appendicitis came to the emergency room. Intraoperatively, destructive diverticulitis and widespread fibrinous-purulent peritonitis were identified. Conversion to a laparotomic approach and expansion of the volume of the main stage of the operation to appendectomy, segmental resection of the ileum were performed. The postoperative period was uneventful. The patient received complex conservative therapy, was discharged on the 10th day in a satisfactory condition.Conclusion. Destructive diverticulitis requires the surgeon to be vigilant in conducting a diagnostic search in the clinical picture of acute appendicitis in adult patients. If a correct intraoperative diagnosis is established, a radical and least traumatic operation should be selected from a rational approach (if necessary, it should be converted to a laparotomic one). It is necessary to emphasize the importance of an individual approach in choosing intraoperative tactics and planning perioperative complex therapy
EYUNOGASTROPLASTICА AS AN EFFECTIVE METHOD FOR PREVENTING FUNCTIONAL DISORDERS AFTER PROXIMAL GASTRIC RESECTION
Authors: Tishakova V. E.
Published: October 2021

The analysis of the results of treatment of 97 patients who were operated from surgical diseases of the cardiac stomach. Proximal gastric resection (PRG) was performed using isoperistaltic jejunogastroplasty (modified by Merendino-Dillard) (50 people – group I) and with direct esophagogastroanastomosis (47 people – group II). 12 and 24 months after the operation, an X-ray and endoscopic examination of the upper digestive tract was performed, assessing the severity of functional disorders (nutritional status, body weight deficiency, reflux esophagitis, anastomosis) Results. After 2 years or more, 5.9% of patients ate more than 6 times a day in group I, while in group II, 23.3% (p <0.05). 67.6% of patients in group I and 36.7% in group II returned to their previous (as before the illness) diet – 3-4 times a day (p <0.05). After 24 months or more, in group II, the average weight of patients did not exceed preoperative indicators (95.9 ± 0.25%), while in group I, there was an increase in the average weight of 109.9 ± 0.13%. (p <0.05). The frequency of reflux esophagitis was observed in 8 (9.3%) cases: in group I – in 2 (4.5%) and in group II-in 6 (14.3%) (p <0.05) According to the authors, the PRG with the reconstruction of the digestive tract according to Meredino-Dilard creates optimal conditions for a faster and better recovery of functional parameters and demonstrates how significant and effective the performed surgical treatment is.
CHEMOEMBOLIZATION OF THE HEPATIC ARTERY IN THE TREATMENT OF PATIENTS WITH CHEMORESISTANT METASTASES OF COLORECTAL CANCER. REVIEW
Authors: Stukalova O. Yu. , Polikarpov A. A. , Isсhenko R. V.
Published: October 2021

In the structure of the incidence of malignant tumors for a number of years, colorectal cancer occupies one of the leading positions, with a steady tendency to growth. The five-year survival rate of patients with metastatic liver damage in colorectal cancer does not exceed 28%. A significant breakthrough in the study of the biology of colorectal cancer has led to a deep understanding of individual processes of carcinogenesis and a personalized approach to treatment tactics. Despite this, the problem of chemoresistance remains one of the most acute. The high toxicity of systemic chemotherapy limits its use in this group of patients. In this connection, minimally invasive and at the same time effective methods of local treatment of malignant liver tumors have been introduced into clinical practice. These methods include: hepatic artery chemoinfusion, chemoembolization, oil chemoembolization and radioembolization. At present, a large world experience has already been accumulated in the application of the above-described methods of treatment. However, the question of the application of methods of interventional surgery in the treatment of patients with chemoresistant metastases is still open. The presented review reflects the results of the analysis of scientific literature on the treatment of this group of patients. The main stages of development and improvement of X-ray endovascular methods of treatment are presented.
Characterizing Magnetic Connectivity of Solar Flare Electron Sources to STEREO Spacecraft Using ADAPT-WSA Modeling
Authors: Petersen A. K. , Kahler S. W. , Henney C. J. , Arge C. N.
Published: October 2021

Onsets and intensity profiles of six energetic (E > 30 keV) electron events common to STEREO A and B (STA and STB) spacecraft were analyzed by Klassen et al. with the STEREO Solar Electron and Proton Telescopes when the spacecraft were separated by <70° in solar longitude. All six events were characterized by earlier onsets and higher peak intensities for the spacecraft with magnetic footpoints at the solar longitudes of larger source separations. The 2.5 Rs footpoint locations, based on Parker spiral (PS) calculations with spacecraft solar wind (SW) speeds V
sw, are compared with 5 Rs footpoint locations calculated by selected realizations of ADAPT-WSA (Air Force Data Assimilative Photospheric flux Transport—Wang–Sheeley–Arge) solar wind (SW) forecast model runs for each spacecraft. ADAPT-WSA footpoint locations support the Klassen et al. results of azimuthally nonuniform injections from two shock-associated events and confirm locations for the flare source event on 2014 July 17. Substantial footpoint differences of the two methods diminish the disparity of the flare event of 2014 May 2 but exacerbate the case of two flare electron events on 2014 August 1. As limited test cases for a comparison of ADAPT-WSA and PS methods at slightly different source surfaces, the Carrington longitude differences range from several to ∼30°. We review the importance and limitations of methods for determining the solar magnetic footpoints for solar energetic particle studies.