bluuebunny/crossref_metadata_2025 huggingface dataset:
Microbial Protein Synthesis by Cellulolytic Bacterial Isolates from Feces of Indonesian Endemic Herbivores
Authors: Pramartaa Ikhsan Qodri , Wiryawan Komang G. , Suharti Sri
Published: August 2024

Cellulolytic bacterial play an important role in the synthesis of microbial protein in the small intestine as high-quality protein. This research aimed to observe the growth patterns of cellulolytic bacterial isolates from the feces of endemic herbivorous animals in Indonesia, and to evaluate the effect of the addition of cellulolytic bacterial isolates on the synthesis of microbial proteins in vitro. The study used a completely randomized design with four treatments and five replications. The treatments included T0 = Concentrate mix 40%: elephant grass 30%: palm leaves 30% (control), T1 = T0 + 105 CFU mL-1 cellulolytic bacterial isolate, T2 = T0 + 106 CFU mL-1 cellulolytic bacterial isolate, and T3 = T0 + 107 CFU mL-1 cellulolytic bacterial isolate. Variables measured were the growth pattern of bacterial isolates, bacterial population at the optimal growth point, and microbial protein synthesis. The results showed growth pattern of cellulolytic bacterial isolates from Muntjac, Deer and Anoa feces have similar pattern, and was different from the growth pattern of bacterial isolates from bison feces. The optimal growth point of cellulolytic bacterial isolates from the feces of Muntjac, Deer, and Anoa at the 8th hour of incubation with bacterial populations of 1.3 x 109 CFU mL-1, 1.7 x 109 CFU mL-1, and 1.4 x 109 CFU mL-1. The growth pattern and optimal point of cellulolytic bacterial isolates from the feces of Bison at the 12th hour after incubation with bacterial populations of 1,1 x 1010 CFU mL-1. The addition of cellulolytic bacterial isolates did not affect microbial protein synthesis.
Alleviating Poverty Through One House One Farm Project in Bangladesh
Authors: Rahman Muhammad Sayadur , Islam Md. Monirul , Ullah Mohammad Nur
Published: August 2024

Poverty is a bad inhalation process in the economic breath system, especially at the rural level in Bangladesh. The one house one farm project was initiated to alleviate poverty in Bangladesh as an initiative of Prime Minister Sheikh Hasina. The project focuses on rural households generating income through family farming with e-financial inclusion or online banking opportunities. The study focuses on the fundamental understanding and reasons for the One House One Farm project. The study follows a generic qualitative method with secondary data sources, including the website of The Project, newspaper articles, and journal articles, to indicate what, how, and why questions. With some beneficiaries' statements, an ethnographic study is conducted as another data collection source. The study introduces a thematic mode of analysis that covers the explanation of the pattern of the One House One Farm project and gives a general idea about the background. The study finds that the One House One Farm project was a primary and better initiative for alleviating or eradicating poverty in Bangladesh, which helps to focus on achieving Sustainable Development Goal- 01. Besides the main target of alleviating or eradicating poverty in Bangladesh, this project helped rural households create a basement for generating income and being free from dependency.
Formulation Facial wash with Addition of Coriander Leaf Extract (Coriandrum savitum L)
Authors: Permana Gusti , Syarbaini Ahmad , Ma'ruf Amar
Published: August 2024

Coriander leaves have functional properties such as antioxidant, antidiabetic, anticholesterol, antimicrobial, anti-inflammatory, and analgesic. Ethanol-extracted coriander leaves exhibit an antioxidant activity of 91.2287 μg/mL. The high antioxidant activity value of coriander leaf extract can be developed into a free radical scavenging product like facial wash. This research aims to determine the physicochemical characteristics of coriander leaf extract facial wash formulations at 10%, 12.5%, and 15% concentrations. Organoleptic sensory and hedonic tests, as well as physicochemical tests, were conducted. The test data were processed using SPSS and subjected to Duncan's post hoc test. The obtained data were then compared with predetermined standards. The resulting coriander leaf (Coriandrum sativum L) facial wash formulation in this study has a semi-solid texture, distinctive aroma, dark brown color, pH ranging from 6.96 to 9.24, foam stability ranging from 82.15% to 92.80%, irritation value ranging from 8.29 to 8.46, and viscosity ranging from 2436.92 cPs to 3236.38 cPs, but it lacks good homogeneity
Study of Making Gluten-Free Fettuccine from Taro Flour (Colocasia esculenta L. Schoot)
Authors: Rahardjo Sekti , Aminudin  , Saleha  , Sriwulandari Tatik , Rahmaniyah Utami Nisa
Published: August 2024

We often encounter fettuccine pasta in cafes and restaurants, usually made from wheat flouras the main ingredient. Wheat flour is a food ingredient that contains gluten, which is a proteincompound from cereals that cause allergies and irritate the small intestine and can also causeceliac (autoimmune) disease in certain people. Several studies have substituted wheat flourfor making fettuccine with non-gluten taro flour. The formula obtained is still a mixture of taroflour and wheat flour. This research used 100% pure taro flour with additional ingredients oftwo types of egg yolk, namely chicken egg yolk and duck egg yolk. This research aimed todetermine the organoleptic results of fettuccine from 100% taro flour based on theformulation using the type of egg yolk and boiling time. This study used a completelyrandomized trial (CRD) design with four treatments and two repetitions. The types oftreatment in this study were the use of duck eggs with a boiling time of 35 seconds, the use ofboiled duck eggs for 1 minute, the use of boiled chicken eggs for 35 seconds, and the use ofboiled chicken eggs for 1 minute. The research results showed that fettuccine was successfullymade using 100% taro flour without being mixed with wheat, using additional egg yolk as abinder. A perfect assessment was obtained from the expert panelists for the duck egg yolkformula boiling for 1 minute. The type of egg yolk and boiling time affect the sample in termsof taste, color, and texture, but not aroma.
Aktivitas Antioksidan dan Karakteristik Kimia Stik Pegagan
Authors: Riski Hapsari Distya , Nurhalimah Siti , Hastuti Arti , Pratami Aprilia
Published: August 2024

Gotu kola leaves contain active compounds which are beneficial for the human body. Gotu kola leaves can be added to processed foods, including sticks. This research added sticks with a concentration of 10%, 15%, and 20% of gotu kola leaves paste. Then, antioxidants activity, crude fiber content, water content, ash content, protein content, fat content, and carbohydrate content were analyzed. After that, gotu kola sticks were selected. Based on research results, the greater the addition of gotu kola leaves, the greater the antioxidant activity, water content, ash content, protein content, and crude fiber content. Gotu kola sticks were selected with the addition of 15% gotu kola leaves. The results of gotu kola chosen sticks had an antioxidant content of 53671.90 ppm, water content 1.32%, ash content 0.99%, protein content 7.75%, fat content 39.04%, carbohydrate content 50.91% and crude fiber 32.20%.
Analisis Studi Kelayakan Usaha Briket Limbah Tongkol Jagung
Authors: Delfitriani Delfitriani , Dzulfiqar Akram , Ariyanto Dodik
Published: August 2024

The use of energy resources that are not environmentally friendly is a problem in Indonesia today. Briquettes are also the primary material because they are abundant, and the primary material has yet to be optimally utilized, including corn cobs. The purpose of this study is to analyze the economic feasibility of corn cob waste briquettes in this study using data analysis of technological technical aspects, financial feasibility analysis such as Payback Period (PP), Net Present Value (NPV), Internal Rate of Return (IRR) and Benefit and Cost Ratio (B/C). The results showed that it takes 19,800 kg of corn cobs to produce charcoal, as much as 3,168 kg and 158.4 kg with tapioca starch adhesive material, as much as 5% of the total weight of charcoal powder, requiring four pieces of equipment, namely pyrolyzer machines, Hammer mills, Planetary mixers, and Tray dryers. Furthermore, the feasibility analysis of this corn cob briquette business was declared feasible with the four categories: Payback Period (PP) for 3.1319 years, Net Present Value (NPV) of Rp 28,129,336,212; IRR of 17.77%, and Net B/C of 1.55. The corn cob briquette agro-industry will remain profitable even if the production capacity decreases by 28% from the original capacity. The agro-industry can also still operate despite an 8% decrease in the selling price of briquettes and will remain profitable if raw materials increase by 17%.
PENINGKATAN KEMAMPUAN LITERASI MATEMATIS SISWA MELALUI PENDEKATAN REALISTIC MATHEMATICS EDUCATION (RME)
Authors: Eftiana Fina
Published: August 2024

This study was motivated by the low mathematical literacy ability in mathematics learning. The purpose of this study was to determine the difference in the average improvement of students' mathematical literacy skills. The research method used quasi experimental with non-equivalent control group research design. The population in this study were all students at SMPN 51 Bandung grade VIII even semester of the 2022/2023 academic year. The samples in this study were class VIII.1 as the experimental class and class VIII.2 as the control class. In the experimental class learning using realistic mathematics education (RME) approach, while in the control class using deductive approach. The data collection technique used was a test. Based on the results of the analysis, it can be concluded that the average increase in students' mathematical literacy skills in learning flat-sided space building using the realistic mathematics education (RME) approach is in the high category has a significant difference compared to using the deductive approach in the medium category. It is recommended that research be carried out using more varied methods and media so that the results obtained are more optimal.
Peran Teknologi Pendidikan Dalam Membantu Siswa Mengatasi Kesulitan Belajar PAI di SMKN 10 Kota Bandung
Authors: Suroya Ai Nurul Wardatul , Ula Muhamad Robiil , Ai Nurajizah
Published: August 2024

Kesulitan belajar merupakan hal yang umum dialami oleh siswa dalam upaya mereka untuk menguasai mata pelajaran di sekolah. Berbagai faktor berkontribusi terhadap tantangan ini, termasuk ketidakmampuan untuk memahami materi sepenuhnya, kurangnya motivasi, dan ketidaktertarikan pada mata pelajaran seperti Pendidikan Agama Islam (PAI). Guru memainkan peran penting dalam membantu siswa untuk mengatasi kesulitan-kesulitan tersebut. Penelitian ini meneliti potensi Teknologi Pendidikan untuk membantu siswa dalam mengatasi tantangan belajar mereka. Penelitian ini menggunakan metodologi penelitian kualitatif untuk mengeksplorasi peran Teknologi Pendidikan dalam membantu siswa mengatasi kesulitan belajar Pendidikan Agama Islam di SMKN 10 Bandung. Temuan menunjukkan bahwa Teknologi Pendidikan memainkan peran penting dalam mengurangi tantangan belajar dalam PAI. Pertama, sebagai media pembelajaran, teknologi membantu memperjelas materi yang sulit, sehingga memudahkan siswa untuk memahami konsep-konsep yang kompleks. Kedua, sebagai sumber belajar, teknologi memfasilitasi akses mudah ke informasi dan konten pendidikan bagi siswa dan guru. Penelitian ini menyoroti pentingnya mengintegrasikan Teknologi Pendidikan ke dalam proses belajar mengajar. Hal ini tidak hanya mengatasi kesulitan belajar tetapi juga meningkatkan pengalaman pendidikan secara keseluruhan dengan membuat informasi lebih mudah diakses dan menarik. Teknologi Pendidikan sangat penting dalam membantu siswa yang mengalami kesulitan belajar PAI di SMKN 10 Bandung. Teknologi Pendidikan berfungsi sebagai media pengajaran dan sumber belajar, sehingga meningkatkan pemahaman dan keterlibatan siswa.
Tantangan dan Solusi dalam Pembelajaran Pendidikan Agama Islam di SMK As-Solehhiyah: Sebuah Studi Kualitatif
Authors: Shella Sulistiawati  , Hayati Fatimah Nurul , Muhammad Ridwan  , Mochammad Gilang
Published: August 2024

Penelitian ini membahas problematika dalam proses pembelajaran Pendidikan Agama Islam (PAI) di SMK As-Solehhiyah. Metode penelitian yang digunakan adalah penelitian kualitatif dengan pengumpulan data melalui observasi langsung, wawancara dengan kepala sekolah, dan guru. Serta dokumentasi. Hasil penelitian menunjukkan beberapa problematika dalam proses pembelajaran PAI, antara lain guru yang kurang disiplin dalam menggunakan waktu dan jarang menggunakan metode pembelajaran yang menarik menjadi salah satu masalah dalam pembelajaran PAI di sekolah ini. Selain itu, masih ada siswa yang belum lancar membaca tulis Al-Qur'an dan fasilitas atau prasarana yang kurang memadai, seperti kekurangan buku PAI dan lab PAI. Upaya yang dilakukan untuk mengatasi masalah tersebut diantaranya kepala sekolah melakukan penilaian terhadap metode pembelajaran dan melihat sejauhmana siswa memahami materi. Namun, belum ada program konkret untuk meningkatkan kompetensi guru. Untuk masalah siswa, jam mata pelajaran PAI yang kurang ditambah dengan banyaknya materi yang tidak tersampaikan dipecah menjadi dua mata pelajaran. Sementara itu, siswa yang belum bisa membaca tulis Al-Qur'an dipisahkan dan diberikan pendekatan khusus diluar jam pelajaran. Masalah fasilitas, seperti kekurangan buku, ditangani dengan Guru memberikan e-book kepada siswa, sedangkan pemenuhan sarana prasarana masih dalam tahap perencanaan.
Implementasi Pendidikan Akhlak Dalam Perspektif Imam Al-Ghazali di SMKN 12 Bandung
Authors: Sahidin Sahidin , Sirojudin Munir  , Khotimah Siti Kusnul , Riss Anita Puspana
Published: August 2024

Penelitian ini bertujuan untuk mengetahui implementasi pendidikan akhlak dalam perspektif Imam Al-Ghazali di SMKN 12 Bandung. Imam Al-Ghazali memaknai akhlak sebagai tatanan yang tertanam kuat dalam jiwa, yang darinya muncul usaha sadar seseorang dalam melakukan hal-hal tanpa membutuhkan pemikiran dan pertimbangan. Penelitian ini menggunakan pendekatan kualitatif dengan mengumpulkan data dari berbagai sumber seperti jurnal, karya ilmiah, buku, dan literatur lainnya. Data dianalisis untuk memahami bagaimana konsep akhlak menurut Imam Al-Ghazali diterapkan di SMKN 12 Bandung. Hasil penelitian menunjukkan bahwa implementasi pendidikan akhlak dalam perspektif Imam Al-Ghazali sudah banyak diimplementasikan oleh peserta didik di SMKN 12 Bandung. Praktik-praktik tersebut meliputi pembiasaan shalat dhuha bersama, membaca Al-Qur’an, membaca Asmaul Husna, berinfaq, dan shalat wajib berjamaah. Implementasi pendidikan akhlak berdasarkan perspektif Imam Al-Ghazali telah diterapkan dengan baik di SMKN 12 Bandung, menunjukkan adanya usaha untuk menanamkan nilai-nilai akhlak yang kuat dalam jiwa peserta didik melalui berbagai kegiatan keagamaan rutin. Dengan demikian, penelitian ini memberikan wawasan tentang bagaimana nilai-nilai akhlak dapat diintegrasikan dalam sistem pendidikan untuk membentuk karakter peserta didik sesuai dengan ajaran Imam Al-Ghazali.
Bankart knee. Operative treatment of posterior part of lateral tibial condyle fracture with concomitant avulsion injury of anterior cruciate ligament (ACL). Technique and case report
Authors:   Ortopedika-Centre for Specialized Surgery, Warsaw, Poland, Bocheński Wojciech , Nawrocki Mateusz ,   Ortopedika-Centre for Specialized Surgery, Warsaw, Poland, Wróbel Mikołaj ,   Ortopedika-Centre for Specialized Surgery, Warsaw, Poland, Sroczyński Juliusz ,   Ortopedika-Centre for Specialized Surgery, Warsaw, Poland, Kłos Grzegorz ,   Ortopedika-Centre for Specialized Surgery, Warsaw, Poland, Mioduszewski Andrzej ,   Ortopedika-Centre for Specialized Surgery, Warsaw, Poland
Published: August 2024

Fractures of the posterolateral part of the tibial plateau (PLTP) are rare and complex fractures among other orthopedic entities. This case report describes a 54-year-old male who suffered a twisting injury of the left knee in a scooter crash. As a result, impaction fracture and displacement of the posterolateral margin of the tibial plateau were diagnosed with concomitant avulsion of the intercondylar eminence of the tibia and medial tibial condyle cleft fracture. The treatment comprised reduction of the medial tibial condyle (MTC) cleft fracture with one cancellous screw, arthroscopic bone-suture of the intercondylar eminence, and reduction of compressed PLTP with fixation of the displaced fragment on a distal radius T-plate working as a “buttress” rather than firm stabilizer. The operative technique of PLTP impaction fracture reduction is described in an instructional manner.
Ankle arthrodesis with a fibular bone autograft and intramedullary nail stabilization in post-traumatic loss of the talus. A case report
Authors:   Department of Orthopaedics and Traumatology, S.T. Dąbrowski District Hospital, Puszczykowo, Poland, Osuch Jakub , Krajewski Maciej ,   Department of Orthopaedics and Traumatology, S.T. Dąbrowski District Hospital, Puszczykowo, Poland
Published: August 2024

Post-traumatic talus bone loss is a rare type of high-energy injury, which is associated with a large decontaminated wound and soft tissue contusion. We found 19 articles in PubMed on 21 patients whose talus was not found at the scene of the accident. We present the case of a 37-year-old patient who experienced post-traumatic talus loss and underwent treatment for talocalcaneal and talonavicular joint arthrodesis six months post-injury. The talus was not recovered at the accident scene. Arthrodesis was stabilized with an intramedullary nail, and a graft from the distal part of the fibula was placed to fill the space between the calcaneus and tibia. Additionally, bone graft and navicular were stabilized with K-wire and arthrodesed. At the one-year follow-up, the patient occasionally experiences foot oedema without pain after a full day of work. X-rays present complete ankle and graft-navicular arthrodesis.
موقف الإمام أبي حنيفة من حديث رسول الله وحجّيته
Authors: Osmani Noor Mohammad , Fuad Iftekhar Jamil
Published: August 2024

Imam Abu Hanifa, may Allah have mercy on him, is one of the four great Imams followed by a vast number of Muslims around the world, and his followers outnumber the rest in the world. There is no doubt that the Imam adhered to the Holy Qur’an, the authentic Prophetic Sunnah, the consensus of the Companions, and sound analogical reasoning. These are the fundamental sources of Islamic jurisprudence in all schools of thought. Despite this, Imam Abu Hanifa has been opposed and criticized by many, with baseless accusations. Some claim that Abu Hanifa had little knowledge of the Prophetic Hadith. Others say he only knew 17 Hadiths, and some go further to assert that he knew only 130 Hadiths, of which he forgot or confused 120, either by altering the chain of transmission or changing the text unknowingly, leaving him with only 10 Hadiths in possession. Is it conceivable that someone with such limited knowledge of the Hadith of the Prophet, peace be upon him, could be among the greatest Imams of the Muslims, followed by the majority of Muslims across the world?
The opinions of scholars about him differ. Some were moderately fair, their piety preventing them from attacking him, while others exceeded all bounds, not fearing any punishment from Allah the Almighty, and thus narrated false accounts. We wish if these people had restrained their tongues out of fear of Allah! Did their piety not prevent them from sharing everything they heard or read with the masses about this great Imam, who met his Lord with a pure and sincere heart? Allah granted him blessings in this world, and in the Hereafter. He will be among the close ones to Allah, leaving behind a lasting legacy. Peace be upon Abu Hanifa al-Nuʿman.
This study addresses the accusations directed at al-Nuʿman—the Greatest Imam—using an inductive, analytical, and critical methodology to establish the truth. Of course, we do not claim that Imam Abu Hanifa was infallible, by Allah! no! No one has the right to make such a claim, not even about the Prophets, except that Allah forgave the Prophets for their past and future sins. This study does not aim to prove that Abu Hanifa, may Allah have mercy on him, was correct and truthful in everything he said, but rather to distinguish truth from falsehood, whether it was said by the Hanafi school, the scholars of Hadith, or other schools of thought. This is what we call upon all esteemed scholars to do, regardless of their affiliations, and without bias.
Sex Education Asertif Normatif untuk Mengurangi Sexual Harassment Remaja Early di Kota Bandung
Authors: Rahayu Citra Resmi , Purba Enjelika , Febriani Nida , Iqbal Muhamad
Published: August 2024

Sex education merupakan topik yang dianggap tabu oleh banyak orang, khususnya di Indonesia. Padahal, pendidikan mengenai seks sangat dibutuhkan oleh semua orang bahkan sejak usia dini. Minimnya pengajaran sex education menimbulkan beberapa efek di kalangan anak muda Indonesia seperti pergaulan bebas, bahkan dapat memberikan efek yang lebih dalam. Dalam pelaksanaannya peneliti memberikan edukasi yang berfokus pada layanan bimbingan ataupun edukasi terhadap kekerasan seksual, dengan mengetahui sex education asertif normatif dapat mengurangi sexual harrasment pada remaja early di SMP Negeri 26 Bandung. Riset ini menggunakan pendekatan kuantitatif, dengan desain pre-eksperimen one group pretest-posttest yaitu melakukan pre-test, treatment dan post-test. Hal ini dikarenakan kelas yang kita gunakan tidak menggunakan kelas control dan treatment yang dilakukan bukan yang umum dilakukan di kelas pembelajaran sekolah. Treatment yang dilakukan berbentuk sosialisasi tentang Sex Education Asertif Normatif Untuk Mengurangi Sexual Harassment Remaja Early. Teknik sampling yang digunakan adalah sampel convenience yaitu menggunakan kelompok-kelompok yang sudah terbentuk secara alamiah misalnya sebuah kelas. Dimana menggunakan teknik random sampling untuk menentukan 93 partisipan dari jumlah populasi 830 siswa. Teknik analisis data riset ini adalah statistik inferensial menggunakan uji normalitas dan uji hipotesis wilcoxon. Hasil riset ini menunjukkan bahwa terjadi peningkatan pada kategori sangat baik pengetahuan mengenai Sex Education Asertif Normatif untuk Mengurangi Sexual Harassment Remaja Early setelah mendapatkan treatment berupa sosialisasi. Sex Education Asertif Normatif untuk Mengurangi Sexual Harassment Remaja Early sangat bermanfaat untuk diimplementasikan pada setiap jenjang Pendidikan menengah untuk mengurangi sexual harassment di kalangan remaja early.
Pemanfaatan Museum Sejarah Al-Qur’an Sumatra Utara sebagai Objek Wisata Edukasi
Authors: Ichwan Azhari  , Kartika Sari  , Ilhan Rayfatsyah Rangkuti  , Salsadilla Nur'aisyah
Published: August 2024

Berdiri pada tahun 2019, Museum Sejarah Al-Qur’an telah banyak mengedukasi para pengunjungnya dengan beberapa koleksi seperti mushaf yang berasal dari Pantai Timur serta beberapa artefak Islam seperti botol kaca, alat medis, batu nisan, koin Umayyah, manik-manik, dan pedang Usmaniyah yang membutikan jejak Islam di Sumatra. Mengembangkan museum perlu strategi dan mempertimbangkan manfaatnya bagi para pengunjung terutama di bidang pendidikan. Menjadikan Museum sebagai tempat yang layak menjadi objek wisata adalah sebuah hal yang penting sehingga ruang lingkup pendidikan menjadi luas dan hal ini menguntungkan pengunjung museum, sehingga konteks belajar tidak hanya di ruang kelas dan konteks wisata tidak selalu sia-sia ketika sudah dilewatkan.
Penanaman Nilai-Nilai Multikultural dalam Tradisi Budaya Lokal di Aceh
Authors: Musthafa Nurul Qhatami , Darmawan Wawan
Published: August 2024

Penelitian ini bertujuan untuk mengetahui bagaimana penanaman nilai-nilai multikultural dalam tradisi budaya lokal di Aceh. Metode yang digunakan dalam penelitian ini yaitu metode kualitatif dengan pendekatan studi pustaka (library research). Hasil yang diperoleh dari penelitian ini menunjukkan bahwa Aceh merupakan provinsi yang multikultral dengan memiliki berbagai suku, bahasa, tradisi, dan budaya. Di Aceh penanaman nilai-nilai multikultural sudah diterapkan yang mana terdapat beberapa nilai-nilai multikultural yang ada dalam kehidupan masyarakat Aceh, yaitu: keanekaragaman, keterbukaan, keadilan, toleransi, harmonisasi, pendidikan, dan kebutuhan akan identitas. Keberagaman masyarakat Aceh yang berasal dari latar belakang yang berbeda seperti suku, agama, ras, budaya, dan bahasa menjadi bukti bahwa masyarakat Aceh merupakan masyarakat multikultural.
Consideration Of the Peculiarities of Non-Drug Rehabilitation Treatment After an Ectopic Pregnancy
Authors: Anatolyevich Bugaevsky Konstantin
Published: August 2024

The features of the application of physical rehabilitation after undergoing an ectopic pregnancy and conducted surgical treatment of severe gynecological pathology requiring emergency care are considered. The program of physical rehabilitation in the early and late postoperative periods, aimed at restoration of reproductive function in patients conducted after surgery tubal ectopic pregnancy options.
The use of Gymnema sylvestre in the treatment of diabetes: The available evidence and expert opinion
Authors: Al-Mosawi Aamir
Published: August 2024

Health supplements have been increasingly used in the prevention and treatment of a diversity of chronic disorders including diabetes. Diabetes has been increasing regarded as an emerging global health problem, and there has been a tendency for therapeutic studies pertaining to diabetes to focus on supplements from natural sources. Research findings have been increasing suggesting the usefulness of several supplements including fenugreek, cinnamon, and lipoic acid in the management of diabetes. During the previous decades, Gymnema sylvestre have been reported to have beneficial effects in diabetes. This paper reviews the available evidence supporting the use of berberine in diabetes with the aim of providing expert opinion. Expert opinion: The available evidence suggests that Gymnema sylvestre has hypoglycemic and lipid lowering effects. However, the available evidence research also suggests the usefulness of several other supplements including fenugreek, cinnamon, and lipoic acid in the management of diabetes. Therefore, the choice of diabetic supplement depends to some extent on the availability and cost. It seems that Gymnema sylvestre is the most available and cost-effective diabetic supplement in India, however, it is not in other counties in the world including Iraq.
Role of Mri in Characterization of Congenital Malformations of Brain in A Tertiary Care Centre-A Retrospective Study
Authors: Datta Debarpita
Published: August 2024

Background: Congenital brain anomalies are rare among the congenital anomalies of various organ systems. It is crucial to recognise these disorders as soon as possible because of the extensive neurological deficiency and negative consequences they can cause. Neuroimaging is a reliable way to accurately diagnose the majority of congenital brain abnormalities. There aren't enough statistics available in developing countries like India about the frequency and types of brain abnormalities. The purpose of this study is to examine the prevalence and range of frequently occurring congenital brain abnormalities. Objective: To study the whole spectrum of all substantial and frequently occurring congenital abnormalities as well as the proportional distribution of the various brain malformations in a tertiary care centre. Methods and materials: The study was conducted at Department of Radio-Diagnosis, Medical College Kolkata from 1st September 2022 to 31st August 2023. All MRI brain examinations at our hospital over a period of one year were retrospectively reviewed and analysed by sex, age at presentation, type of congenital cerebral malformation, and other associated congenital cerebral malformations. Results: This study included 24 patients. The total number of brain malformations identified in these patients was 33. The age of patients at first MRI imaging ranged from 5 days to 16 years. There were 14 males and 10 females. The most common malformations were corpus callosum dysgenesis (24%), Heterotropia (15%) and Lissencephaly (12%). Seven patients (29.1%) had more than one congenital brain malformation. Conclusion: The variety and complexity of congenital brain abnormalities is remarkable. The correct diagnosis is essential for the best care of these unfortunate conditions, and MRI plays a significant role in this process. Identification of distinctive neuroimaging findings of various congenital brain anomalies are immensely helpful in diagnosing the anomalies and further management.
Advances in Endocrinology: Bridging Research and Clinical Practice
Authors: Pandey Ashish
Published: August 2024

The field of endocrinology has witnessed remarkable advancements in recent years, significantly impacting the diagnosis, management, and treatment of endocrine disorders. This editorial provides a comprehensive overview of these advancements, emphasizing the integration of cutting-edge research into clinical practice. Key areas of focus include novel diagnostic techniques, personalized medicine, advancements in diabetes management, thyroid disorders, and the role of technology in enhancing patient outcomes. By bridging the gap between research and clinical practice, these developments promise to improve the quality of life for patients with endocrine disorders.
Struktur Komunitas Makrozoobentos di Setapuk Besar Kalimantan Barat
Authors: Ramadhan Bayu , Minsas Sukal , Sofiana Mega Sari Juane
Published: August 2024

Penelitian ini bertujuan untuk mengetahui kelimpahan dan keanekaragaman makrozoobentos di Setapuk Besar, Singkawang, Kalimantan Barat. Penelitian ini dilakukan pada bulan April – Juni 2022. Penentuan stasiun penelitian dilakukan dengan metode purposive sampling, berdasarkan rona lingkungan. Stasiun I berada di pemukiman, Stasiun II berada di dermaga kapal, dan Stasiun III berada jauh dari pemukiman dan dermaga kapal. Makrozoobentos diambil dari sampel sedimen. Sedimen diambil dengan coring berdiamater 2,5 inchi sedalam 40 cm. Hasil penelitian menunjukkan bahwa komposisi makrozoobentos yaitu 4 kelas dan 18 jenis. Kisaran indeks keanekaragaraman makrozoobentos 1,5-2,0 dikategorikan sedang, indeks keseragaman makrozoobentos 0,77-0,96 dikategorikan tinggi, indeks dominansi makrozoobentos 0,14-0,32 dikategorikan sedang.
Pengembangan E-Modul Terintegrasi Informasi COVID-19 Untuk Meningkatkan Hasil Belajar Biologi
Authors: Alif Yanuar Zukmadini  , Neni Murniati  , Bhakti Karyadi  , Irwandi Ansori  , Syaiful Rochman
Published: August 2024

Pandemi Covid-19 memberikan pengaruh terhadap proses dan hasil belajar siswa.  kelas. Bahan ajar yang baik memuat materi yang kontekstual dan dapat digunakan untuk mencapai tujuan pembelajaran. Penelitian ini bertujuan untuk mengembangkan e-modul terintegrasi informasi COVID-19 yang valid, praktis, dan efektif untuk meningkatkan hasil belajar biologi siswa kelas X SMA. Jenis penelitian ini adalah R&D menggunakan model 4D oleh Thiagarajan yang terdiri dari tahap Define, Design, Develop, dan Disseminate. Berdasarkan hasil penelitian, diperoleh persentase kevalidan e-modul dari ahli bahan ajar sebesar 95,60% (sangat valid), ahli materi sebesar 96,57% (sangat valid), dan Praktisi (guru) sebesar 96,05% (sangat valid). Adapun persentase kepraktisan e-modul sebesar 87,5% (sangat praktis). Hasil N-Gain pada uji coba skala terbatas memiliki nilai 0,34 (sedang), sedangkan pada uji coba skala luas, nilai N-Gain kelompok kontrol sebesar 0,26 (rendah) dan nilai N-Gain kelompok eksperimen sebesar 0,53 (sedang). Nilai signifikansi N-Gain yang diperoleh dari uji independent sample t saat uji coba skala yaitu < 0,05, sehingga terdapat perbedaan yang signifikan antara peningkatan hasil belajar siswa di kelas kontrol dan kelas eksperimen. Kesimpulan dari penelitian ini adalah E-modul terintegrasi informasi COVID-19 adalah bahan ajar yang valid, praktis, dan efektif untuk meningkatkan hasil belajar biologi siswa pada materi virus di kelas X SMA.
Kata Kunci: E-Modul, Bahan Ajar COVID-19, Virus, Hasil Belajar Siswa Pada Masa Pandemi.
La salud infantil y el ambiente. Exposición a pesticidas de poblaciones vulnerables
Authors: Mesquita Ramirez Mirta Noemi , Cabral de Bejarano Maria Stella
Published: August 2024

Los pesticidas son un grupo de compuestos químicos que tienen diferentes acciones, insecticidas, fungicidas, herbicidas, rodenticidas. Luego de su aplicación,el proceso de degradacion es lento. Pueden permanecer en el suelo y en las aguas subterráneas, contaminando el agua.
El cambio climático transforma el proceso de degradación de los compuestos químicos, por la alteración de la composición del suelo, produciendo alteraciones en el  ecosistema y la biodiversidad.El impacto de los pesticidas sobre la salud humana es un desafío por el gran potencial de daño que tienen.Desde el año 2004, se introduce en Paraguay las semillas geneticamente modificadas, acompañado de un gran incremento de las areas de cultivo y la utilizacion de pesticidas.Con el objetivo de revisar el estado del conocimiento actual sobre los efectos de estas sustancias quimicas, sobre los diferentes organos y sistemas  en las poblaciones pediatricas y embarazadas, se realizo una revision descriptiva, abarcando las principales base de datos disponibles.Como objetivo secundario, considerando la extension de areas de cultivo en Paraguay, describir  los resutlados de los estudios realizados en el pais.
Los resultados de los estudios revisados muestran asociacion entre afectacion de diferentes organos, sistemas, de estas poblaciones y la exposcion ambiental, de las aguas y  los alimentos. Algunos de estos resultados se replican en los realizados en las zonas de cultivo del pais.
Prevención de Infecciones Respiratorias por VSR: Consenso Interinstitucional
Authors: Martínez de Cuellar Celia , Campuzano de Rolón Ana , Giménez Edgar , Weber Ernesto , Lovera Dolores , Rolón Roger , Pavlicich Viviana , Jimmy Jiménez Hassel , Benítez I Irene , Ruíz Zorrilla Carolina , Irrazbal María , Ovelar Patricia , Suarez Zully , José Sánchez María , Velázquez Sheila , Estigarribia Gladys , Moreno Luis , Aguilar Gloria , Modesto Araujo José , González de Soto Mirta , Ghesi Cristina , Godoy Laura , Castro Héctor , Fonseca Rosanna
Published: August 2024

Las infecciones por el VSR en constituyen una causa importante de morbilidad, hospitalización, ausentismo escolar y laboral, así como de mortalidad, en el mundo, así como en el Paraguay. En la actualidad, existen herramientas para la prevención del VSR. En el año 2012, el Paraguay, ha incorporado el palivizumab (MedImmune, EE. UU.), anticuerpo monoclonal, producido por tecnología de DNA recombinante. Este anticuerpo se administra en 5 dosis, cada 30 días y está indicado en lactantes nacidos prematuros y aquellos con trastornos cardiopulmonares.
Por otro lado, actualmente se cuenta con una nueva herramienta para la prevención del VSR. El anticuerpo monoclonal de vida media prolongada Nirsevimab, específico para la conformación de prefusión de la proteína F, aprobado por EMA y FDA. Este monoclonal, está indicado para la prevención de las Infecciones respiratorias agudas bajas, causada por VSR en recién nacidos y lactantes nacidos durante o al ingresar a su primera temporada de VSR, en prematuros y lactantes hasta los 24 meses de edad que siguen siendo vulnerables a la enfermedad grave por VSR durante su segunda temporada de VSR.
Luego de analizar la situación epidemiológica del VSR en el país así como la evidencia de eficacia, eficiencia y efectividad de este monoclonal; instituciones académicas, sociedades científicas, organizaciones no gubernamentales y gubernamentales se reunieron y elaboraron un consenso interinstitucional para la prevención de las infecciones por VSR, sugiriendo la incorporación del Nirsevimab, en menores de 12 meses de edad antes de su primera temporada de VSR y en reemplazo del Palivizumab, debido a que el nuevo monoclonal tiene el potencial de cambiar el panorama de las infecciones por VSR en el lactante y producir un impacto en la reducción la mortalidad y morbilidad infantil; reduciendo la carga al sistema de salud, en lo que se refiere a la disminución de la ocupación de camas hospitalarias tanto en sala como en unidades de cuidados intensivos, así como la disminución de la carga para los cuidadores, médicos y proveedores de atención médica y la mortalidad infantil.
Effect of Plyometric Training on Flexibility of Balochistan Female Cricket Athletes
Authors: Aslam Muhammad , Shah Faiz ul Hassan , Ullah Kaleem
Published: August 2024

The study sought to determine the impact of a 12-week plyometric workout regimen on the flexibility of female cricket players in Balochistan. Twenty participants were divided into two groups: an experimental group that received plyometric workouts, and a control group that wasn't involved in any specific physical activity program. Flexibility was assessed using the sit-and-reach test, and anthropometric characteristics were measured before and after the training period. The results showed a significant increase in flexibility in the experimental group compared to the control group. Additionally, the experimental group exhibited significant changes in weight and waist-hip ratio post-intervention. These findings suggest that plyometric training can effectively improve flexibility in female cricket athletes.Additional studies might concentrate on the long-term consequences of plyometric training and address potential limitations such as diet and weather conditions to enhance understanding further.
Functional mapping of movement and speech using task-based electrophysiological changes in stereoelectroencephalography
Authors: Jensen Michael A. , Fine Anthony , Kerezoudis Panagiotis , Wong-Kisiel Lily , Alden Eva C. , Hermes Dora , Miller Kai J.
Published: August 2024

OBJECTIVE

Stereoelectroencephalography (SEEG) has become the predominant method for intracranial seizure localization. When imaging, semiology, and scalp EEG findings are not in full agreement or definitively localizing, implanted SEEG recordings are used to test candidate seizure onset zones (SOZs). Discovered SOZs may then be targeted for resection, laser ablation, or neurostimulation. If an SOZ is eloquent, resection and ablation are both contraindicated, so identifying functional representation is crucial for therapeutic decision-making. The authors present a novel functional brain mapping technique that utilizes task-based electrophysiological changes in SEEG during behavioral tasks and test this in pediatric and adult patients.

METHODS

SEEG was recorded in 20 patients with epilepsy who ranged in age from 6 to 39 years (12 female, 18 of 20 patients < 21 years of age) and underwent implanted monitoring to identify seizure onset. Each performed 1) visually cued simple repetitive movements of the hand, foot, or tongue while electromyography was recorded; and 2) simple picture-naming or verb-generation speech tasks while audio was recorded. Broadband changes in the power spectrum of the SEEG recording were compared between behavior and rest.

RESULTS

Electrophysiological functional mapping of movement and/or speech areas was completed in all 20 patients. Eloquent representation was identified in both cortex and white matter and generally corresponded to classically described functional anatomical organization as well as other clinical mapping results. Robust maps of brain activity were identified in healthy brain, regions of developmental or acquired structural abnormality, and SOZs.

CONCLUSIONS

Task-based electrophysiological mapping using broadband changes in the SEEG signal reliably identifies movement and speech representation in pediatric and adult epilepsy patients.
A survey of the members of the American Society of Pediatric Neurosurgeons and factors associated with well-being
Authors: Roe Avery , Flannery Ann Marie , Hamilton Kimberly , Kanev Paul , McBride Lori A. , Oluigbo Chima , Raskin Jeffrey S. , Tovar-Spinoza Zulma , Tu Albert , Weiner Howard L. , Weprin Bradley , Hsu Chiu-Hsieh , Grant Gerald A. , Avellino Anthony M.
Published: August 2024

OBJECTIVE

The goal of this study was to survey the members of the American Society of Pediatric Neurosurgeons (ASPN) to assess the prevalence and associated risks of burnout among pediatric neurosurgeons. The authors aimed to identify the factors that most significantly contributed to this risk to provide a baseline group of characteristics to improve physician well-being.

METHODS

Institutional Review Board approval from the University of Arizona was obtained, and the 7-question and 9-question Mayo Physician Well-Being Index (WBI) was distributed to members of the ASPN (n = 275). This index screens for many different aspects of distress for physicians, including burnout risk, stress, depression, fatigue, suicidal ideation, and low career satisfaction.

RESULTS

An analysis of 111 pediatric neurosurgeons (111/275 [40% response rate]) was completed. Respondent ages were distributed, with those aged 56–60 years representing the highest proportion (20%). University practice represented a majority (72%). One-third (32%) of respondents reported practicing greater than 25 years, and most physicians in the survey were married (76%). One-third of surgeons spend 61–70 hours working per week (33%), and a plurality are on call between 6 and 10 days per month (42%). Most surgeons reported treating fewer than 200 cases per year (37% reported 100–150 cases; 23%, 151–200). Most pediatric neurosurgeons (63%) stated their annual salary was sufficient. Analysis of each WBI question was performed to identify which factors specifically contributed to the risk of burnout. An overwhelming majority of respondents reported that they make significant efforts to do at least one thing each week that brings them joy (97%), and they either agree or strongly agree that they perform meaningful work (98% of all participants, 97% of females, and 98% of men, p = 0.010). Nearly half of all respondents (49%) reported feelings of burnout and a majority of them were female (67% of women and 42% of men, p = 0.021). Time, environment, case volumes, and quality-of-life concerns are all factors that significantly contribute to the overall risk of burnout and well-being.

CONCLUSIONS

This survey study of the ASPN membership revealed a 49% rate of burnout with females at higher risk (67%). Factors associated with burnout were salary, more than 10 days on call per month, electronic medical record stressors, and work-life incongruity. The aforementioned notwithstanding, respondents believe pediatric neurosurgery is a meaningful career. This study provides evidence supporting a moral imperative toward recognition of burnout symptoms and a pivot point toward implementing change.
Uji Aktivitas Formula Sediaan Masker Gel Peel Off Ekstrak Etanol Buah Patikala (Etlingera eatior (Jack) R.M Smith) terhadap Pertumbuhan Bakteri Penyebab Jerawat
Authors: Suleman Abdul Wahid , Latu Saparuddin , Padjalangi Andi Muh Yagkin , Jangga Jangga
Published: August 2024

Buah Patikala memiliki senyawa flavonoid digunakan untuk menghambat mikroba. Tujuan penelitian untukmmengetahui ekstrak buahjpatikala dapat diformulasikan dalam masker peel off  yang secara fisika dan kimia serta untuk mengetahui seberapa  besar konsentrasi dari ekstrak buah patikala yang dapat menghambat bakteri penyebab jerawat. Jenis penelitian ini merupakan eksperimental meliputi evaluasi masker peel off secara fisik dan kimia serta pengujian aktivitas formula masker gel peel off ekstrak etanol buah patikala terhadap zona hambat pada bakteri penyebab jerawat yang terbagi mejadi 5 kelompok. Hasil penelitian menunjukkan bahwa ekstrak etanol buah patikala dapat diformulasikan serta stabil dalam bentuk sediaan masker gel peel off dan memiliki aktivitas antibakteri. Konsentrasi pada formula III merupakan konsentrasi yang memiliki aktivitas antibakteri paling optimal terhadap bakteri Propionibacterium acnes dengan luas zona hambat 9,91±0,18 mm. Konsentrasi pada formula III merupakan konsentrasi yang memiliki aktivitas antibakteri paling optimal terhadap bakteri Staphylococcus epidermidis dengan luas zona hambat 9,25±0,27mm.
Penggunaan Obat Off-Label Pada Pasien Anak Di Puskesmas Deket Kecamatan Lamongan
Authors: Susanti Irma
Published: August 2024

Penggunaan obat off-label pada pasien anak diperlukan monitoring yang ketat untuk menghindari efek yang tidak dikehendaki. Efek samping dan risikonya mungkin lebih besar daripada potensi manfaatnya. Penelitian ini bertujuan untuk mengetahui penggunaan obat off-label pada pasien anak berdasarkan dosis, usia/ berat badan dan indikasi. Penelitian ini merupakan jenis penelitian deskriptif, pengumpulan data secara retrospektif, menggunakan data resep pasien anak di Puskesmas Deket Lamongan. Penelitian ini juga dilakukan analisis data untuk mengetahui obat off-label kategori usia/berat badan, dosis, dan indikasi obat. Penelitian ini dilakukan pada bulan Januari-Agustus 2021 menggunakan total sampling. Dari 471 resep ditemukan off-label dosis sebanyak 68(65%), Off-label usia sebanyak 20 (19%), Off-label indikasi sebanyak 17(16%). Dilihat dari kategori off-label diketahui bahwa off-label dosis ditemukan lebih banyak daripada off- label usia dan off-label indikasi. Off-label dosis banyak ditemukan karena kurangnya informasi dosis pediatrik, kurangnya formulasi pediatrik yang tepat, kurangnya data uji klinis. Penelitian peresepan obat off-label tinggi sehingga perlu pemilihan obat yang tepat serta monitoring dalam penggunaan obat pada anak.
Skrining Fitokimia dan Penetapan Kadar Tanin Ekstrak Daun Litsea elliptica Blume
Authors: Chandra Pra Panca Bayu
Published: August 2024

Litsea elliptica merupakan jenis yang berasal dari genus Litsea yang tumbuh di daerah tropis yang memiliki sekitar 45 genus dan lebih dari 2.000 spesies. Indonesia merupakan negara tropis di Asia Tenggara dengan genus tumbuhan yang beragam, salah satu Pulau yang banyak ditemukan Litsea adalah Pulau Kalimantan. Potensi sebagai obat yang berasal dari bahan alam memiliki peluang sebagai bahan baku obat tradisional. Metabolit sekunder yang terkandung dalam daun Litsea elliptica yaitu flavonoid, alcohol aromatic, fenolik, asam lemak, triterpen, asam ftalat monoester, furaldehide. Penelitian ini bertujuan untuk mengetahui kandungan fitokimia dan kadar tannin total ekstrak daun Litsea elliptica. Proses ekstraksi dilakukan secara maserasi dengan pelarut etanol 96%. Hasil ekstraksi maserasi kemudian dilakukan proses penguapan hingga diperoleh ekstrak kental. Skrining fitokimia terhadap ekstrak kental yang diperoleh menggunakan pereaksi kimia. Hasil skrining fitokimia diperoleh bahwa ekstrak daun Litsea elliptica mengandung alkaloid, saponin, tannin, fenolik, flavonoid, triterpenoid, steroid, glikosida dan minyak atsiri. Kandungan tannin total ditetapkan menggunakan Metode Folin Denis dengan instrumen spektrofotometri UV-Vis diperoleh kadar tannin total ekstrak daun Litsea elliptica sebesar sebesar 2661,22 mg/100 gram dengan nilai SD 24.