bluuebunny/crossref_metadata_2025 huggingface dataset:
Avaliação da área de disposição final de resíduos sólidos de um município de pequeno porte mediante os critérios técnicos e ambientais
Authors: Silva Galilleu , Lopes Adriana Antunes , Silva Júnior Édio Damásio da , Sales Abner Santos Baroni
Published: July 2020

A problemática dos resíduos sólidos, assim como a grande rede do sistema capitalista, vem acarretando impactos irreversíveis ao meio ambiente, colocando em risco os bens a se proteger para as presentes e futuras gerações, devido à quantidade e a variedade de resíduos dispostos de forma desordenada no meio ambiente. Entretanto, no que é referente à Gestão de Resíduos Sólidos, cada vez mais são conquistados avanços como a Lei nº 12.305/2010, que institui a Política Nacional dos Resíduos Sólidos (PNRS), que trouxe diretrizes e metas como a disposição final ambientalmente adequada dos rejeitos. Estes, por sua vez, devem ser dispostos em aterros sanitários que são, do ponto de vista econômico/ambiental/social, a melhor alternativa para a disposição final dos resíduos sólidos. Assim, objetivou-se neste trabalho avaliar a área de disposição final de resíduos sólidos urbanos no município de Santa Helena de Goiás - GO, comparando sua atual situação com o que é regido pela PNRS. Para isso foram realizadas visitas in loco, consultas a normas técnicas, documentos e processos que transcorrem acerca da área de estudo. Foi constatada uma série de impactos ambientais, tais como: poluição do solo, da água e do ar; presença de vetores e catadores; saturação da vala, ausência de compactação dos resíduos, dentre outras adversidades técnicas e operacionais.
Análise da evolução do planejamento ambiental do parque zoológico de Goiânia
Authors: Guimarães Cibele de Moura , Pasqualetto Antonio
Published: July 2020

Os parques urbanos são locais fundamentais para o equilíbrio ser humano natureza. Entretanto, quando se trata de um parque Zoológico, acrescenta-se a presença dos animais, além da vegetação, recursos hídricos, solo e demais constituintes do ambiente, que podem afetar a qualidade de vida e o equilíbrio ambiental na cidade. O objetivo do estudo foi realizar análise do processo de planejamento ambiental do Parque Zoológico de Goiânia. Em 2019 realizou-se análises de imagens satélites do Google Earth Pro obtendo-se evolução temporal para verificar a situação quanto aos aspectos ambientais vegetação e recursos hídricos, impactos e ações. Constatou-se que em 1990 foi o último registro de reflorestamento no Zoológico de Goiânia. Entre os anos 2005, 2007 e 2009 não são perceptíveis alterações da área florestada. Em 2007 também houve a oficialização do quinto Plano Diretor de Goiânia. Conclui-se que o parque zoológico, apesar de momentos críticos ao longo da história, recebeu ações para mitigarem impactos ambientais, especialmente reflorestamento e adequações dos espaços dos animais.
The role of cytoreductive nephrectomy in renal cell carcinoma patients with liver metastasis
Authors: Guo Boda , Liu Shengjing , Wang Miao , Hou Huimin , Liu Ming
Published: July 2020

It is widely accepted that renal cell carcinoma with liver metastasis carries a dismal prognosis. We aimed to explore the value of cytoreductive nephrectomy among these patients. Patients were extracted from the SEER database between 2010 and 2017. The univariate and multivariate Cox proportional hazards models were conducted to select the prognostic predictors of survival. Patients were divided into nephrectomy and non-nephrectomy groups. Propensity score-matching analyses were applied to reduce the above factors’ differences between the groups. Overall survival was compared by Kaplan-Meier (K-M) analyses. Data from 683 patients was extracted from the database. The univariate Cox regression and multivariate Cox regression revealed that factors including age, histologic type, T and N stages, lung metastasis, brain metastasis, and nephrectomy were significant predictors of survival in the patients. After the propensity score-matching analyses, we found that nephrectomy prolonged overall survival. Nephrectomy can prolong overall survival in eligible renal cell carcinoma patients with liver metastasis.
Freezing cancer cell lines v1
Authors: Souster Emily , Goodwin Verity , Jackson Adam , Beaver Charlotte , Ansari Rizwan , Behan Fiona , Garnett Mathew
Published: July 2020

This protocol outlines routine banking of cancer cell lines and Ca9 transduced cancer lines. Process diagram:
Clever Pennies: Honesty Oaths, Misreporting Performance, and MTurk v1
Authors: Jobu Babin J , Chauhan Haritima , Liu Feng
Published: July 2020

Workers in online labor markets routinely misrepresent the value of effort, both through shirking and misreporting performance. We execute a field experiment on Amazon MTurk to determine whether honesty oaths impact the cost of worker lies. Employing a design that follows the “die roll” paradigm, we determine that oaths elicit more truthful behavior, although they primarily impact extreme lies. Oath-taking decreased the cost of misreportingby 12%. While shirking is widespread, oaths marginally decrease it. Male workers misreport performance more often on average than females, yet both sexes are equally responsive to oath-taking. JEL Codes: D90, D91, C8, C93, J9
Fixing Cell Pellets for Flow Cytometry v2
Authors: Goodwin Verity , Souster Emily , Garnett Mathew , Behan Fiona , Beaver Charlotte , Ansari Rizwan , Jackson Adam
Published: July 2020

This protocol is designed to outline the process of fixing cell pellets in 1.5ml tubes. It has been developed within the Cellular Generation and Phenotyping Group at the Wellcome Sanger Institute. Process diagram:
Magnetic field frequency optimisation for MFL imaging using QWHE sensors
Authors: Watson J M , Liang C W , Sexton J , Missous M
Published: July 2020

Magnetic particle and other magnetic flux leakage (MFL)-based methods for the detection and evaluation of surfacebreaking flaws in ferromagnetic materials typically use high-strength (∼0.5 T RMS) low-frequency (≤50 Hz) magnetic fields. The rationale behind this is the ready availability
of strong permanent magnets and mains power for highstrength electromagnets. This high field strength is needed to saturate the sample and compensate for the insensitivity of magnetic particles, silicon Hall sensors, coils and other magnetic transducers. Consequently, the frequency of the
applied magnetic field is typically limited to ≤50 Hz and does not consider the frequency response of the material under test (some MFL applications use this low frequency to detect subsurface or flaws on the backwall). In this study, a probe consisting of a quantum well Hall-effect (QWHE)
sensor, an illuminating electromagnet and sensor circuitry was controlled using an automated XYZ scanner with an x-y measurement step size (ie magnetic image pixel size) of 100 microns. This probe was used to apply magnetic fields of various frequencies (DC to 1 kHz) and field strengths (5
mT to 100 mT) to ascertain a frequency and field range best suited to detecting 10 mm- and 11 mm-long longitudinal surface-breaking toe cracks in ground mild steel welds. A lift-off distance of <1 mm was controlled using a proximity laser and a z-direction motor module to autonomously control
the probe lift-off and conform to sample geometry. This study found that an applied magnetic field with a frequency of 800 Hz and a field strength of 10 mT RMS was optimal under the constraint of power consumption, based on the ratio of MFL responses from the two flaws and the weld. It was
found that other frequency field combinations had comparable or higher detection but were discounted as they had substantially higher power consumption.
Clinical profile and laboratory characteristics of dengue fever in children: analysis of 2019 outbreak from Bengaluru, Karnataka, India
Authors: Shankar Poornima , Mahamud Shajna
Published: July 2020

Background: Dengue, an endemic disease in most subtropical and tropical regions of the world is causing severe epidemics in India. An alarming rise of dengue has also been seen in India during the recent years. Majority of dengue viral infections are self-limiting, but complications may cause high morbidity and mortality. Present study was undertaken with an objective of describing various clinical presentations as noted in our cohort of dengue patients and to evaluate the outcome of dengue fever.Methods: This retrospective study included all confirmed dengue cases below 18 years age admitted to Paediatric department of KIMS, Bengaluru over a period of 1 year in 2019. Medical records were reviewed and analysed. Those diagnosed to be positive for dengue serology (NS1 or IgM) were included in our study. Dengue was classified according to the WHO guidelines into 2 groups, Dengue fever (without/with warning signs) and Severe Dengue. Clinical features, haematological, biochemical, radiological parameters, management and the outcome were assessed.Results: Out of 441 patients enrolled, 79% had non-severe dengue and 21% severe dengue. The commonest age of presentation was above 10 years with mean age of 8.68±5.25 years. Male to female ratio was 1.7:1. 60% presented within 4 to 7 days of illness (mean 4.26±1.72 days). Majority presented with fever (88%). 47% had vomiting and 31% abdominal pain. Bleeding manifestations were seen in 18%. Dengue serology was positive for NS1Ag (58%), IgM (21%), mixed (21%). Thrombocytopenia and leukopenia seen in 82% and 39.45% respectively. The association between dengue serology and platelet count was statistically significant (p value 0.001). 46% had raised SGPT. 31% had evidence of plasma leakage. The case fatality rate was 0.2%.Conclusions: High grade fever, vomiting, abdominal pain and bleeding manifestations with normal or low platelet count were the presenting features. Early diagnosis, monitoring and prompt supportive management can reduce mortality.
Correlation of gestational age assessed by last menstrual period and New Ballard’s Score in pre term babies
Authors: S. Krithika , V. Rajanish K. , E. Adarsh
Published: July 2020

Background: Gestational age is a critical factor in the management, decision making and follow up of new born infants. Identification of gestational age especially within 48 hours of life is crucial for new born. Since decades attempts have been made to find an alternative measurement for gestational age and birth weight estimation of the newborns. Last menstrual period is an inexpensive method and potentially efficient for calculating gestational age. Objective of this study was to the present study aims to compare the gestational age by New Ballards score with LMP, in pre term babies.Methods: A total 150 pre term babies who are born to mothers remembering LMP were enrolled for the study group. During the study period new Ballard scoring was done for babies within 48hrs and Gestational age was compared with LMP. The collected data was analyzed by using SAS-6.50 version. Study design a prospective observational study was conducted over a period of one year from January 2018 till December 2018 at Rajarajeswari Medical College and Hospital, Bengaluru, IndiaResults: The New Ballard score is found to be significantly correlated with GA above 29 weeks (p<0.01). The LMP mean was 35±2.0 weeks. Total 60.6 % of the childbirth is lead to normal vaginal delivery. The analysis shows LMP were found to be strongly correlated with GA (p<0.01).Conclusions: LMP alone can be reliably used in assessing the gestational age and can be assessed more accurately and be confirmed with new Ballard’s scoring for preterm babies of >29 weeks.
Chronic granulomatous invasive fungal rhinosinusitis in Nigeria: challenges of management
Authors: Asoegwu Chinyere N. , Oladele Rita O. , Kanu Okezie O. , Nwawolo Clement C.
Published: July 2020

Background: Chronic granulomatous invasive fungal rhinosinusitis affects mainly immunocompetent patients and has been widely reported in tropical regions such as South East Asia and North Africa. Nigeria has a tropical climate, however, there is paucity of data on this disease condition in Nigeria. This study documents the clinical, diagnostic, therapeutic challenges of managing patients with this condition in Nigeria.

Methods: A retrospective study of patients diagnosed and treated for chronic granulomatous invasive fungal rhinosinusitis between 2010 and 2019. Diagnosis was based on clinical presentation, computed tomographic scan findings and confirmed by histopathology and/or microbiology results.  

Results: Ten patients aged 12 to 49 years with mean age of 33.9±13.8 years were studied. Male to female ratio was 2.3:1. All were immunocompetent. Duration of symptoms before presentation ranged from 3 months to 8 years with a mean duration of 3.5±2.4 years. Commonest clinical presentation was unilateral proptosis 80% followed by nasal mass 50%. Commonest sinus involved was the ethmoid (80%). There was orbital extension in 70% and intracranial involvement in 50%. Aspergillus species was the commonest fungal agent cultured. Treatment was by surgical excision followed by antifungal drugs. Some of the challenges we encountered in the management included; late presentation, delay in diagnosis, limited experience in histopathologic and mycology diagnosis and high cost of treatment amidst scarce resource.

Conclusions: Chronic invasive granulomatous rhinosinusitis is not rare in Nigeria. A high index of suspicion is however needed for the diagnosis. Development of a National management protocol for this disease is recommended to avoid misdiagnosis.

 
Prevalence of aminoglycoside therapy and other determinant factors that induce hearing loss in neonates
Authors: Hamad Nassor R. , Andrajati Retnosari , Mutiara Rina , Kaban Risma Kerina , Das Rajesh Kumar
Published: July 2020

Background: Hearing loss is the most common disorder in neonates; it can be best managed if it is diagnosed at early stage of life. The global prevalence of permanent neonatal hearing loss mainly occurs in developing countries, which accounts 0.5 to 5.0 per 1000 live births. The objective of this study was to determine the prevalence of aminoglycoside therapy and other risk factors that induce hearing loss in neonates admitted at NICU at Cipto-Mangunkusumo General Hospital (CMGH).

Methods: This was a case-control study conducted among 112 neonates at Cipto-Mangunkusumo General Hospital (CMGH). Data from neonatal hearing screening were retrospectively collected from hospital electronic medical records and medical files. Only patients treated at neonatal unit from November 2018 to October 2019 were recruited.  

Results: Out of 112 neonates studied, the gestational age at birth (GA) and craniofacial anomalies were considered risk factors for hearing loss since they were statistically significant (p<0.05). The study showed no statistical significant association in gender, birth weight, mechanical ventilation, NICU stay period (>5 days), hyperbilirubinemia (>20 mg/dl), asphyxia, and aminoglycoside therapy (p>0.05).

Conclusions: The prevalence of hearing loss in neonates with lower gestational age less than 37 weeks and craniofacial anomalies are significant higher compare to neonates born full term. They are more associated with 3 and 6 times increased risk of hearing loss in neonates.
Postoperative mastoid cavity problems: a tertiary care centre experience
Authors: Saraf Aditiya , Ahmad Raies , Jyoti Deep , Kalsotra Parmod
Published: July 2020

Background: Aims and objectives of the study were to find incidence and causes for postoperative mastoid cavity problems after modified radical mastoidectomy.

Methods: The present prospective study was conducted in the Department of ENT, SMGS Hospital, GMC Jammu from September 2017 to February 2020 on 25 patients with active squamosal chronic otitis media. All patients underwent modified radical mastoidectomy after taking written and informed consent. A period of 3 months postoperatively was taken as a healing time for complete epitheliasation of cavity. Any patient presenting with symptoms beyond this period was considered a cavity problem case.

Results: Out of 25 patients, 9 patients had cavity problems, the incidence of cavity problem being 36%. Perforation in tympanic membrane was seen in 7 patients (77%) and high facial ridge in 2 patients (22%). There was no case of narrow meatoplasty in our study.

Conclusions: Incidence of mastoid cavity problems can be reduced if the open cavity procedures are executed adequately.
Invasive fungal granuloma: a diagnostic challenge
Authors: Thaduri Abhinav , Sreekanth G. , Vishnuvardan Dipin Kumar , Reddy K. Sravani
Published: July 2020

Invasive fungal rhinosinusitis is a rare and life-threatening with high mortality and morbidity. Granulomatous invasive fungal rhinosinusitis has a time course exceeding 12 weeks. This disease has been reported primarily in south of Asia, however, it is very rare. When the invasive fungal sinus infection presents in a form of a granuloma with unusual presentation then they pose a diagnostic challenge to medical professionals. We present a case series of 3 cases of invasive fungal granuloma with varied presentations, which posed as a challenge in diagnosing them. Chronic invasive fungal granuloma (CIFG) of the paranasal sinuses is seen in immunocompetent hosts, especially those that are in the 3rd and 4th decades of their lives. Involvement of maxillary sinus and orbit is common than the sphenoid sinus involvement. Routine H and E staining may prove inadequate. Special stains such as the GMS stain should be employed in the slightest doubt of a fungal aetiology. A team approach towards patients is paramount for early diagnosis and timely medical and surgical intervention.
Parathyroid adenoma: a case report
Authors: Kantharia Shehnaz R. , Kantharia Rajesh A. , Reddy Pradeep K. , Mistry Yogesh M.
Published: July 2020

The incidence of primary hyperparathyroidism in India is 2.5/1000 individuals. Primary hyperparathyroidism can be caused by a non-cancerous parathyroid adenoma, hyperplasia or rarely by parathyroid carcinoma. Most of these patients have few or no symptoms. Correct diagnosis can be reached by clinical settings, biochemical and radiological tests and final confirmation by histopathology of the specimen.
Hoarseness after spinal anesthesia: a case report
Authors: Sharma S. P. , Singh Anuj , Karan Awanish , Kumar Ajay , Brashier D. B. S. , Vishal Dimple
Published: July 2020

Hoarseness is a common entity encountered post intubation in cases operatively managed under general anaesthesia and during regional anaesthesia mainly in cervical/brachial plexus block as a consequence of involvement of phrenic nerve. Limited reports of hoarseness, associated with spinal anaesthesia (sub arachnoid block) in obstetric and gynecology cases have been documented by various authors. Here we document a case of hoarseness in 24-year-old parturient lasting for 10-14 days, after spinal anaesthesia with bupivacaine (H) for lower segment caesarean section. The hoarseness in this case can be due to unilateral vocal cord palsy as a consequence of high-level sympathetic blockade by administration of sub arachnoid block or vagal neuropathy due to intracranial hypotension, as a consequence of spinal fluid egress from dural puncture site. However, in our case no evidence of post dural puncture headache (PDPH) due to egress of cerebrospinal fluid from puncture site was noted, interestingly pointing towards lower pressure change threshold for occurrence of vagal nerve and vocal cord palsy viz PDPH.
Recurrent dermatofibrosarcoma protuberans of head and neck with fibrosarcomatous change: a challenge for the head and neck surgeon
Authors: Ramamourthy Balaji , Arora Kanika , Thirunavukkarasu Balamurugan , Ramavat Anurag S. , Bal Amanjit
Published: July 2020

Dermatofibrosarcoma protuberans (DFSP) of head and neck is a rare, slow growing, intermediate to low grade malignant soft tissue neoplasm with high rates of local recurrence requiring multiple surgeries posing great distress for both the patient and treating physician alike. Fibrasarcomatous change is a very rare occurrence in such tumors increasing risk of distant metastasis. We report such a rare case of recurrent DFSP with fibrosarcomatous change of the head and neck region, the management protocol and the key points a surgeon should keep in mind while treating such patients.

 
Palestine and the Habeas Viscus
Authors: Alijla Abdalhadi
Published: July 2020

Borders have been a political tool to control, manipulate and affect the lives and movements of individual and groups. These borders can also work as barriers designed to discriminate against specific ethnic, religious, or linguistic groups and individuals for political reasons. In specific cases, borders can create an entire generation of exception, where the lives of a particular age group matter less than others. Palestinians in Gaza have been living in a state of exception, where their lives have been animalized and constrained both within the Gaza Strip and also outside the Gaza Strip, at border points of entry in many places. This paper is an autoethnography of the lives of Palestinians as a state of exception, visa violence, airports and borders. Borrowing Weheliye’s concept of  habeas viscus, the paper examines and describes experiences such as visa applications, rejections, travel, and encounters with border officials. The article starts with describing the state of exception of Gazans who were born and grew up under Israeli occupation. The paper then examines and analyzes the process and ritual of traveling as a quasi-citizen through various border points of entry. This article is an anthropological narrative of how a continuous state of exception turns individuals into homo sacer.
Reduced live birth rates in frozen versus fresh single cleavage stage embryo transfer cycles: A cross-sectional study
Authors: Tinn Teh Wan , Polyakov Alex , Garrett Claire , Edgar David , Adrian Walton Rogers Peter
Published: July 2020

Background: Studies have suggested that embryo-endometrial developmental asynchrony caused by slow-growing embryos can be corrected by freezing the embryo and transferring it back in a subsequent cycle. Therefore, we hypothesized that live birth rates (LBR) would be higher in frozen embryo transfer (FET) compared with fresh embryo transfers.
Objective: To compare LBR between fresh and FET cycles.
Materials and Methods: A cross-sectional analysis of 10,744 single autologous embryo transfer cycles that used a single cleavage-stage embryo was performed. Multivariate analysis was performed to compare LBR between FET and fresh cycles, after correcting for various confounding factors. Sub-analysis was also performed in cycles using slow embryos.
Results: Both LBR (19.13% vs 14.13%) and clinical pregnancy (22.48% vs 16.25%) rates (CPR) were higher in the fresh cycle group (p < 0.00). Multivariate analysis for confounding factors also confirmed that women receiving a frozen-thawed embryo had a significantly lower LBR rate compared to those receiving a fresh embryo (OR 0.76, 95% CI 0.68-0.86, p < 0.00). In the sub-analysis of 1,154 cycles using slow embryos, there was no statistical difference in LBR (6.40% vs 6.26%, p = 0.92) or CPR (8.10% vs 7.22%, p = 0.58) between the two groups.
Conclusion: This study shows a lower LBR in FET cycles when compared to fresh cycles. Our results suggest that any potential gains in LBR due to improved embryo-endometrial synchrony following FET are lost, presumably due to freeze-thaw process-related embryo damage.
Key words: Fresh, Frozen embryo transfer, Live birth, Embryo, Transfer.
Detection of human herpes viruses 1-5 in miscarriage: A case-control study
Authors: Charostad Javad , Mokhtari-Azad Talat , Yavarian Jila , Ghavami Nastaran , Mahmood Seyed Khorrami Seyed , Behboudi Emad , Jalilvand Somayeh , Shatizadeh Malekshahi Somayeh , Zahra Shafiei-Jandaghi Nazanin
Published: July 2020

Background: Miscarriage is the spontaneous pregnancy loss before 24 wk of gestation. The incidence rate of miscarriage over the past few decades has shown steady or even growing trends. Viral intrauterine infections are one of the probable etiological causes of miscarriage. Previous evidence have shown that human herpes viruses (HHVs) could be considered as the potential reasons for intrauterine infections and adverse pregnancy outcomes.
Objective: This case-control study aimed to detect HHV1-5 DNAs in placental tissues and assess their association with miscarriage during the first 24 wk of pregnancy in spontaneous and therapeutic abortions.
Materials and Methods: Placental tissues from 83 women with spontaneous abortions during the first and the second trimesters of pregnancy and 81 women with therapeutic abortion during the same gestational age were collected. The DNA extraction was performed by the phenol/chloroform method. A part of the DNA polymerase gene of HHVs was amplified with multiplex nested-polymerase chain reaction. The polymerase chain reaction products were subjected to sequencing.
Results: The results showed the presence of human cytomegalovirus genome in the placenta of both spontaneous (8.4%) and therapeutic (4.9%) abortions. No statistically significant differences were found between these two groups. The other investigated viruses were not detected here.
Conclusion: In conclusion, like some other studies, no correlation was detected between the HHVs placental infections and the increased risk of spontaneous abortions. In order to find the actual role of HHVs infections in miscarriage, further investigations should be performed on a larger sample size in different areas.
Key words: Spontaneous abortion, Therapeutic abortion, Infections, Human herpes viruses.
mtDNA deletions responsible for unsuccessful pregnancy after in- vitro fertilization
Authors: Finsterer Josef , Alexandre Scorza Fulvio , Alessandra Scorza Carla , Claudia Fiorini Ana
Published: July 2020

This is a Letter to the Editor and does not have an abstract.
Construcción de una mesa de succión de doble capa de bajo costo para definir macroporosidad (porosidad drenable) y microporosidad
Authors: Chavarría-Vidal Adrián Enrique , Honorio de Miranda Jarbas , Farias-Ramírez Asdrubal
Published: July 2020

La necesidad de conocer la porosidad drenable del suelo o macroporosidad con fines de manejar correctamente el agua en el suelo, sea ésta con fines de riego o con fines de drenaje ha tomado cada vez mayor relevancia. Para ello existen equipos que se ofrecen en casas comerciales generalmente de costos altos. No obstante, conociendo la física del agua en una matriz arenosa se puede construir una mesa de succión (mesa de tensión) con arena llamada comúnmente caja de arena para estimar la macro y microporosidad y como tal la porosidad total presente en un suelo.
Las micro porosidades obtenidas para un suelo arenoso expresado en contenido de humedad volumétrica sometido a una succión de 60 cmca (centímetros de columna de agua) y a 100 cmca fueron 11,12% y 5,73% respectivamente y las macro porosidades obtenidas y expresadas en términos de porcentaje de humedad volumétrica para un suelo arenoso sometido a una succión de 60 cmca y a 100 cmca fueron 25,14% y 30,53%.
Indywidualny akt administracji gospodarczej (próba zdefiniowania)
Authors: Dubiński Łukasz
Published: July 2020

Celem artykułu jest zaproponowanie definicji pojęcia indywidualnego aktu administracji gospodarczej, rozumianego jako instrument służący ustalaniu sytuacji prawnej przedsiębiorcy. Przy okazji dowiedziono, że cechą odróżniającą indywidualne akty administracji gospodarczej od innych aktów władzy publicznej jest to, iż omawiane rozstrzygnięcia zapadają w wyniku przeprowadzenia procesu wyważania pomiędzy wolnością gospodarczą a innymi wartościami, które są chronione na poziomie regulacji ustrojowych. Przeprowadzone analizy mają służyć realizacji wyzwania po-legającego na zbudowaniu jednolitej siatki pojęciowej, mającej na celu potwierdzenie odrębności publicznego prawa gospodarczego jako samodzielnej gałęzi prawa.
Wprowadzenie do aksjologii prawa gospodarczego publicznego
Authors: Powałowski Andrzej
Published: July 2020

Potrzebna jest refleksja filozoficzna nad prawem gospodarczym publicznym, a w szcze-gólności poczynienie ustaleń dotyczących wartości leżących u podstaw tej dogmatyki. Wartości należy w pierwszej kolejności odpowiednio zidentyfikować i ustalić ich źródła. Problemem jest ich stopień akceptacji przez ustawodawcę, wyrażający się w treści norm stanowionych, oraz rola i znaczenie wartości w procesie stosowania prawa. Wartości określają ład w obszarze gospodar-ki, wpływają na relacje między organami państwa a przedsiębiorcami oraz na sferę wykonywania działalności gospodarczej. Stanowią też niezbędną przesłankę formułowania zasad prawa. Wolność wykonywania działalności gospodarczej odpowiednio skonfigurowana z potrzebą realizacji interesu publicznego to wartości charakteryzujące i wyróżniające prawo gospodarcze publiczne.
Rynek hurtowy energii elektrycznej jako instrument regulacji sektora elektroenergetycznego w Unii Europejskiej i na Ukrainie
Authors: Kosiński Eryk
Published: July 2020

W publikacji dokonuje się analizy obowiązujących regulacji prawnych Unii Euro-pejskiej oraz Ukrainy w zakresie organizacji i funkcjonowania rynku hurtowego energii elek-trycznej. Obowiązująca unijna regulacja prawna pozwala na stwierdzenie, że realizowane są trzy główne cele regulacji: cele ekonomiczne (w tym w zakresie wspierania konkurencji), cele z zakresu zapewnienia bezpieczeństwa energetycznego oraz cele społeczne. W konsekwencji należy uznać rynek hurtowy energii elektrycznej za instrument regulacyjny. Ukraina przyjęła na siebie obowiązek wdrożenia przepisów unijnych w zakresie regulacji sektora energetycznego (acquis communautaire Wspólnoty Energetycznej). Ustawa Ukrainy z dnia 13 kwietnia 2017 roku o rynku energii elektrycznej w zakresie organizacji i funkcjonowania rynku hurtowego energii elektrycznej wdraża do ukraińskiego porządku prawnego podstawowe zasady trzeciego pakietu energetycznego. Wymagane jest jednak dalej idące dostosowanie prawa ukraińskiego do rozporządzenia 1227/2011 (tak zwany REMIT) oraz do przyjmowanych aktów czwartego pakietu energetycznego.
Ograniczenia dystrybucji selektywnej przez platformy online — uwagi na tle sprawy Coty
Authors: Kostecka-Jurczyk Daria
Published: July 2020

W związku z dynamicznym rozwojem sprzedaży internetowej coraz większą popu-larnością cieszą się selektywne systemy dystrybucji. Jednocześnie coraz częściej w ramach tych systemów dostawcy ograniczają sprzedającym na dalszym łańcuchu dystrybucji możliwość wy-korzystania internetu jako kanału sprzedaży. Takie praktyki skłaniają do pytania, czy ograniczenia kanałów dystrybucji online są dopuszczalne w świetle prawa konkurencji. Trudno jednoznacznie odpowiedzieć na pytanie, czy producent lub wyłączny dystrybutor może ograniczyć sprzedaż nie-autoryzowanym dystrybutorom na niższym szczeblu rynku, zwłaszcza sprzedaż poprzez platformy internetowe należące do osób trzecich. W opracowaniu dokonano analizy selektywnego systemu dystrybucji z punktu widzenia dozwolonych ograniczeń sprzedaży głównie w oparciu o orzeczenie wstępne TSUE w sprawie Coty. Wykorzystano także orzecznictwo sądów niemieckich. W efekcie wykazano, że — co do zasady — niedopuszczalne jest ograniczanie sprzedaży przez internet, ale rezygnacja z konkretnego kanału dystrybucji online (na przykład platform należących do osób trze-cich) jest możliwa.
Concordancia entre la radiografía panorámica y la tomografía computarizada de haz cónico en la relación de los terceros molares mandibulares con el conducto dentario inferior
Authors: Herrera Mujica Raúl Rafferty , Ríos Villasis Liz Katty , León Manco Roberto Antonio , Beltrán Silva Jorge Artur
Published: July 2020

Objetivo: determinar la concordancia entre la radiografía panorámica y la tomografía computarizada de haz cónico en el análisis de la relación de los terceros molares mandibulares con el conducto dentario inferior en una población peruana. Material y métodos: la investigación fue observacional, descriptiva, transversal y retrospectiva. La muestra fue de 112 terceros molares y para la evaluación radiográfica se utilizó la clasificación modificada de Robert Langlais. Así mismo, otras variables fueron edad, sexo y lado. Las pruebas estadísticas empleadas fueron chi cuadrado, prueba U de Mann Whitney, prueba de Kruskall Wallis y el Índice de Kappa de Cohen. Resultados: según la radiografía panorámica, el 82,1% (n=92) de los terceros molares presentó superposición, del cual el mayor porcentaje fue para el signo “discontinuidad” con 25,9% (n =29). Según la tomografía computarizada de haz cónico, el 65,2% (n=73) de los molares presentó “contacto”. El signo radiográfico “banda oscura + discontinuidad” tuvo una correspondencia del 88,9% (n=24) con la presentación tomográfica de “contacto”. Conclusiones: existe una baja concordancia diagnóstica entre la radiografía panorámica y la tomografía computarizada de haz cónico en el análisis de la relación del tercer molar mandibular con el conducto dentario inferior. Además, no existe diferencia estadísticamente significativa de esta relación con el sexo, ni con la edad y ni tampoco con el lado.
La actuación sobre el medio urbano de regeneración y renovación integrada. El nuevo paradigma de la gestión urbanística en suelo urbanizado = The integrated regeneration and renovation in the urban intervention. The new paradigm of city planning management
Authors: Cerezo Ibarrondo Alvaro
Published: July 2020

ResumenLa actuación sobre el medio urbano de regeneración y renovación integrada (aMU-RRi) configura el nuevo paradigma de la intervención urbana, la preservación urbana con carácter conjunto e integrado. Para ello redefine la viabilidad económica, afecta el deber de conservación del derecho de propiedad a la actuación y articula un modelo de equidistribución de reparto de costes que supera las pautas del urbanismo que hemos conocido.El presente artículo constituye un breve recorrido histórico por los instrumentos y técnicas que ha dispuesto el urbanismo español para la preservación urbana: desde inviable e insostenible modelo clásico del urbanismo, pasando por el modelo de la sostenibilidad que incorporó la sostenibilidad plena y el régimen estatutario del derecho de propiedad, pero que estableció un régimen general de intervención sobre el suelo urbanizado inviable y dejó un hueco falto de regulación para la preservación de la ciudad; para alcanzar la definición de la aMU-RRi con la legislación del modelo por la ciudad y sus adaptaciones autonómicas de medio urbano y que ayudará a la formación del nuevo paradigma urbanístico, basado en la función social del derecho de propiedad que nos hemos dado para la preservación urbana conjunta e integrada de eso que llamamos, la ciudad.AbstractThe integrated urban regeneration and renewal intervention (aMU-RRi) configures the new paradigm of urban intervention, with its joint and integrated character for urban preservation. To this end, it redefines the economic viability, affects the duty of preservation of the right of property and articulates a model of equistribution of distribution of costs that surpasses the urban planning guidelines that we have known.This paper constitutes a brief historical journey through the instruments and techniques that Spanish urban planning has provided for urban preservation: from an unviable and unsustainable classic urban planning model, through the sustainability model that it incorporated full sustainability and the statutory property rights regime, but that established an unviable general intervention regime in the existing city areas and also left a gap due to the lack of regulation for the preservation of the city; and finally up to the definition of the aMU-RRi with city preserving legislation and its regional adaptations and that will help the formation of the new urban paradigm, based on the social function of property rights that we have been given for the joint and integrated urban preservation of what we call, the city.
Fréquences alléliques de la caséine αS1 chez les boucs d’insémination de race Alpine et Saanen de 1975 à 1994
Authors: RICORDEAU G. , MANFREDI E. , PIACERE A. , AMIGUES Y.
Published: July 2020

Les fréquences alléliques en caséine αS1 ont été calculées à partir des 761 boucs d’IA nés de 1975 à 1994, dont 483 Alpins et 278 Saanen. Dans ces 2 races, le même schéma de sélection a entraîné une évolution différente des fréquences alléliques. Chez les boucs Alpins de testage et améliorateurs, la fréquence de l’allèle "fort" A n’a cessé d’augmenter (0,70 en 1994) aux dépens des allèles E et F. Chez les boucs Saanen, l’allèle E reste majoritaire et a même tendance à augmenter (0,69 en 1994) aux dépens de l’allèle F, alors que la fréquence de l’allèle A augmente peu. L’allèle "fort" B est rare dans les 2 races, mais tend à se fixer en race Alpine, alors que l’allèle "fort" C absent en race Saanen, tend à disparaître en race Alpine. Cette évolution moins favorable à la Saanen, s’explique par une plus faible fréquence initiale des allèles "forts", un effet défavorable du prétestage - reproduction, un niveau de sélection plus faible pour le taux de protéines, et des effectifs plus réduits. Cette évolution doit être corrigée si l’on souhaite améliorer la richesse en protéines vraies et protéines coagulables du lait des chèvres Saanen.
Scissor-Hinged Deployable Structures Supported Perimetrally on Rectangular Bases
Authors: Freire-Tellado M.J. , Muñoz-Vidal M. , Pérez-Valcárcel J.
Published: July 2020

Deployable bar structures on a rectangular base present the problems of closing the ends and longitudinal stabilization. Some proposals have been made to resolve them, mainly by creating mouths, but their application to composite geometries is problematic.
 On-the-bias deployable
structures adequately solve both problems as they are supported around their entire perimeter, have a strong three-dimensional operation and only use load-bearing bars. The text analyses this type of deployable structures, their requirements and possibilities.
 A study on the combination
of polar and translational units in a single deployable structure is then carried out, focusing on the study of on-the-bias deployable structures with perimeter polar modules that allow the effective height of the designs to be increased. Finally, the architectural possibilities of the system
are studied, which make it possible to resolve overhangs, vertical openings in the roof, and T- or L-shaped ground plans, guaranteeing the modularity of the system.
COVID-19 pathophysiology may be driven by a loss of inhibition of the Renin-Angiotensin-Aldosterone System
Authors: Rysz Susanne , Al-Saadi Jonathan , Sjöström Anna , Farm Maria , Jalde Francesca Campoccia , Plattén Michael , Eriksson Helen , Klein Margareta , Vargas-Paris Roberto , Nyrén Sven , Abdula Goran , Ouellette Russell , Granberg Tobias , Fagerlund Malin Jonsson , Lundberg Johan
Published: July 2020

SARS-CoV-2 enters the cell through the ACE2 receptor, which is considered one of the main inhibitors in the Renin-Angiotensin-Aldosterone System (RAAS).1​ ,2 The virus has been shown to downregulate the ACE2 receptor, leading to a subsequent increase in the vasopressoragentangiotensinII.3​ Evidently,criticalcoronavirusdisease2019(COVID-19)is thought to be due to a dysregulated immune response, causing a cytokine-release syndrome eventually leading to acute respiratory distress syndrome (ARDS).4​ ,5 ​However, several reports on clinical laboratory features and case-descriptions of critically ill patients with COVID-19 show discrepancies compared to typical ARDS. Here, we show that infusing swines with angiotensin II induces a pathophysiological syndrome closely resembling that of patients with RT-PCR-positive COVID-19. By using multimodal clinical imaging of patients, comparing laboratory data and translational histological features, we show that it is highly likely that an increase in RAAS is one, if not the main, pathogenic feature in critical COVID-19. Furthermore, it is plausible that this large animal model can be used to screen for potential new treatments for patients with severe COVID-19 and that MRI lung perfusion can be used to evaluate the outcome of potential treatments targeting the pathophysiological syndrome.
Empowering Healthcare Volunteer’s through Participatory Action Research in a Comprehensive Healthcare Center
Authors: Vizeshfar Fatemeh , Momennasab Marzieh , Yektatalab Shahrzad , Iman Mohamad Taghi
Published: July 2020

Background: healthcare volunteers act as the link between the society and the healthcare system and are a symbol of people's participation in the health maintenance and promotion. Despite the important role of health volunteers in the health system, it seems they experience several problems. The aim of this study was empowering health volunteers by determining and relining their problems through a participatory approach.Methods: This study a participatory action research was done through two continuous cycles of reflection and acting for change over 20 months, in A comprehensive health center in Southern of Fars province in Iran.25 health volunteers, two instructors, and academic researcher as facilitator participate in this study. In the first cycle, the participants discovered the challenges of health volunteers prioritized them and an action plan was designed. Immersion and implementation of the plans were done. At the end of this cycle evaluation was done with the participants’ cooperation. The second cycle began with reflecting on the results of the first cycle and final evaluation was done. Results: Qualitative content analysis in the first phase led to the emergence of four major categories, including inefficiency of volunteers training, inefficiency of attraction and maintenance of volunteers, and being unknown to people and the major theme was named “unfertilized capacity”. After the implementation of the operational plan, the participants learned through reflection and immersing in action. Finally, quantitative content and data analysis showed improvement of knowledge and performance, satisfaction, effectiveness of programs and improvement in volunteer’s competence.Conclusions: Clarification of volunteers’ roles, supporting volunteers to improve their knowledge and skills with coherent planning based on their educational needs, are appropriate management plans to attract and retain volunteers. By presenting their services to the society, they will be empowered and motivated to continue.
Use of Machine Learning to Investigate The Quantitative Checklist For Autism in Toddlers (Q-CHAT) Towards Early Autism Screening
Authors: Tartarisco Gennaro , Cicceri Giovanni , Pietro Davide Di , Aiello Stefania , Leonardi Elisa , Marino Flavia , Chiarotti Flavia , Gagliano Antonella , Arduino Giuseppe Maurizio , Apicella Fabio , Muratori Filippo , Team Toddlers , Bruneo Dario , Allison Carrie , Cohen Simon Baron , Vagni David , Pioggia Giovanni , Ruta Liliana
Published: July 2020

Background: In the past two decades, several screening instruments have been developed to detect toddlers who may be autistic, both in clinical and unselected samples. Among others, the Quantitative CHecklist for Autism in Toddlers (Q−CHAT) is a quantitative and normally distributed measure of autistic traits which demonstrated good psychometric properties in different settings and cultures. Recently machine learning (ML) has been applied to behavioural science to improve classification performance of autism screening and diagnostic tools, but mainly in children, adolescents and adults. Methods: In this study, we used machine learning (ML) to investigate the accuracy and reliability of the Q−CHAT in discriminating young autistic children from those without. Three different ML algorithms (Random Forest, Naive Bayes and Support Vector Machine) were applied to investigate the complete set of Q-CHAT items and the best predictive items. Results: Our results showed that the three selected models outperformed the classical statistical methods of predictive validity and among the three ML classifiers, the Support Vector Machine was the most effective, being able to classify autism with 95% accuracy. Furthermore, using the Support Vector Machine-Recursive Feature Elimination approach we were able to select a subset of 14 items ensuring an accuracy of 93%, while an accuracy of 83% was obtained from the best 3 discriminating items in common to our and the previous reported Q-CHAT-10. Limitations: Further data collection is needed.Conclusions: This evidence confirms the high performance and cross-cultural validity of the Q-CHAT and supports the application of ML to create shorter and faster versions of the instrument maintaining high classification accuracy, to be used as a quick, easy and high-performance tool in primary care settings.
New Perception of the Optical Solutions to the Fokas-Lenells Equation According to Two Different Techniques
Authors: Zahran Emad , Shehata Maha
Published: July 2020

In this article, the perturbed Fokas-Lenells equation (FLE)” which plays a vital role in modern asocial media and electronic communication” is employed. Two important different methods are invited to demonstrating new accurate solutions of this equation. The first method is the modified simple equation method (MSEM) that reduces large volume of calculations and realizes closed form solution. While the second is the modified extended tanh-function method (METFM) “which controlled by the auxiliary Ricatti equation” and used effectively to obtain accurate solutions Furthermore, few of the realized results are compatible with that obtained by previous authors elsewhere the others remains new. In addition to the varitional iteration method (VIM )is applied perfectly to achieved the numerical solution corresponding to the exact solution realized by each one of these methods individually.
6 Cases of Breast Cancer-Associated Neoplastic Meningitis and Literature Review
Authors: Fan Jingyi , Gao Ping , He Junying , Zou Yueli , Yan Litian , Zhao Yue , Bu Hui
Published: July 2020

Background: Neoplastic meningitis refers to malignant tumors invading the meninges and subarachnoid spaces, causing intracranial metastases similar to meningitis. Discovery of tumor cells in the cerebrospinal fluid is the gold standard for its diagnosis. In China, meningeal metastasis of breast cancer is a relatively rare type. Methods: The clinical characteristics, imaging data, cerebrospinal fluid cytology and treatment options of 6 patients with meningeal metastasis of breast cancer treated in our hospital were analyzed. Results: The median age of Neoplastic meningitis was 50 years old. The cerebrospinal fluid pressure of the 6 patients increased to varying degrees and tumor cells were found in the cerebrospinal fluid. Of the 6 patients, 2 received only supportive care, and the rest received chemotherapy and intrathecal injection. The shortest survival time was 1 week, and the longest survival time was over 33.2 weeks. Conclusions: Patients whose initial Karnofsky Performance Scale scores were good and who received active and regular treatment after the diagnosis of NM had long overall survival time.
Exodus probabilities from a structural-zero category: Illustration of public knowledge, perception, and communication on COVID-19
Authors: Shanmugam Ramalingam , Singh Karan P
Published: July 2020

Background: Medical and healthcare professionals and governing agencies have faced big challenges to control, intervene and prevent the spread of COVID-19. In analysis of survey data on COVID-19, some practiced probability laws are nullified. Among those probability laws, the structural-zero (different from sampling zero) category with respect to the people’s knowledge, perception, and communication about the COVID-19 pandemics occurs in surveys is an example.Results: Exodus probabilities are derived and utilized. Using a recent survey data on COVID-19, the proposed method to configure such probabilities (proportions) is illustrated.Conclusion: The research question is about a way to configure the proportions who might have transited from the structurally zero category to other viable categories. This research question is answered in a novel manner.