bluuebunny/crossref_metadata_2025 huggingface dataset:
Outcome of Tapering Enteroplasty in Managing Jejunoileal Atresia
Authors: Aboalazayem Abeer , Ragab Moutaz , Magdy Abdelaziz , Bahaaeldin Khaled , Shalaby Aly
Published: November 2022

Background:

Jejunoileal atresia (JIA) represents a common cause of neonatal bowel obstruction. There is a discrepancy between the diameters of the proximal and the distal bowel loops and this is managed with excision or tapering of the dilated proximal bowel loop. We aim primarily to evaluate the outcome of tapering enteroplasty (TE) in managing JIA and secondarily to compare the outcome of TE to non-TE.

Materials and Methods:

A retrospective analysis of records of all neonatal admissions with JIA from January 2017 to December 2018 at a tertiary university children's hospital. Type and location of atresia, time to full enteral feeds, length of stay (LOS), complications, and outcome were assessed in TE and non-TE groups.

Results:

Forty-one patients were included in the study; 29 (70.7%) cases had jejunal atresia and 12 (29.3%) had ileal atresia. Seventeen (41.4%) patients had TE. The median days to full feeds was 19; 28 in the TE group versus 16 in the non-TE group (P = 0.022). Four (9.7%) cases needed a re-exploration because of failure to start feeds; all in the non-TE group. The median LOS was 33 days for TE versus 22 days for non-TE (P = 0.101). Twenty-one cases (51.2%) developed a wound infection and showed a significantly longer median LOS of 29.5 versus 19 days (P = 0.019). Mortality was 7 (17.1%).

Conclusions:

TE did not show a superior outcome when compared to resection of the dilated bowel. It was associated with longer time to reach full enteral nutrition and longer LOS.
MTHFR C677T and MTR A2756G Gene Polymorphism in Neural Tube Defect Patients and Its Association with Red Blood Cell Folate Level in Eastern Indian Population
Authors: Kumari Rekha , Kumar Santosh , Thakur Vinit Kumar , Singh Kalpana , Kumar Uday
Published: November 2022

Introduction:

Single-nucleotide polymorphism (SNP) is a single-nucleotide change in a deoxyribose nucleic acid (DNA) sequence that occurs in >1% of population. Methylene tetra hydro folate reductase (MTHFR) C677T (rs1801133) and methionine synthase enzyme (MTR) A2756G (rs1805087) are two such SNPs occurring in coding sequence of the respective genes, which are frequently seen with neural tube defects (NTDs). MTHFR and MTR genes are involved in folate metabolism. The folate level in the course of pregnancy is treated as vital in the etiopathogenesis of NTDs. This study aims to explore the association of SNPs of both genes and red blood cell (RBC) folate levels in the predisposition to NTDs.

Aims and Objective:

The purpose of this investigation was to determine the relationship of NTDs with polymorphisms in MTHFR and MTR genotype and to estimate and compare the RBC folate levels in NTD patients and controls.

Materials and Methods:

A total of 397 individuals were enrolled (163 patients and 234 controls) for this observational study. Genotyping to find out MTHFR C677T and MTR A2756G was performed by polymerase chain reaction–restriction fragment length polymorphism technique from DNA extracted from the subject's blood. RBC folate level was estimated by chemiluminescence immunoassay method with the same blood sample.

Results:

The total RBC folate levels were significantly less among cases compared to controls (P = 0.020). A significant difference for RBC folate was observed between case and control groups of various genotypes of MTHFR C677T, except heterozygote CT (P = 0.459). Among MTR A2756G, genotypes with only homozygous AA have significant difference (P = 0.003) for RBC folate levels. Among different types of NTDs, there were no significant differences for RBC folate levels. Among MTHFR C677T, T allele possessed 1.9 times risk compared to C allele for the occurrence of NTDs. In MTR A2756G polymorphism, the odds of developing NTDs were 1.6 times in heterozygous AG compared to homozygous AA. Similarly, the risk for NTDs was three times higher in subjects with both heterozygous AG and CT genotypes compared to wild-type homozygous AA and CC genotypes.

Conclusion:

The total RBC folate levels were significantly less among cases compared to controls, and the genotypes had no such effect in decrease in RBC folate levels. The presence of mutant allele in homozygous or heterozygous condition for both SNPs had increased risk associated with NTDs.
Complications and Management of Retained Double-J Stents in Children During the Coronavirus Disease-2019 Pandemic
Authors: Divya Gali , Kundal Vijay Kumar , Shah Shalu , Debnath Pinaki Ranjan , Meena Atul Kumar , Sen Amita
Published: November 2022

Background:

Double-J (DJ) stents were commonly used for internal drainage after major reconstructive procedures or in cases of obstruction and ureteral injuries. They should be removed or changed within the stipulated time; otherwise, they can lead to various complications such as stent occlusion, migration, breakage, encrustation, stone formation at either end of the stent, and entanglement of the two stents if bilateral stenting was done. The present study focuses on the complications and the management due to delay in the removal of the DJ stents due to the coronavirus disease-2019 pandemic.

Materials and Methods:

This is a cross-sectional study over a period of 9 months. Children <12 years were included in the study. The patients' demographic data, indication for DJ stenting, time gap between DJ stenting and removal, complication with delay in DJ stent removal, and its management were recorded. Indwelling duration for >4 months was considered a delay in removal. All patients were followed up for 3 months.

Results:

A total of 10 patients were included in the study. Encrustation, proximal migration, distal migration, knotting of the stent, and entanglement of the bilateral stents in the bladder were observed. These complications were managed by various endourological procedures such as ureteroscopy, percutaneous nephroscopic, and cystoscopic removal. During follow-up, all patients were symptom-free.

Conclusion:

Prolonged indwelling stents can cause various complications. Endourological procedures are an essential armamentarium for a pediatric surgeon to manage these complications. Proper patient counseling regarding indwelling stents and maintaining stent registry and sending automatic messages and e-mails to patients may prevent these complications.
A converse statement to Hutchinson’s theorem and a dimension gap for self-affine measures
Authors: Morris Ian D. , Sert Çağrı
Published: November 2022

A well-known theorem of J. E. Hutchinson states that if an iterated function system consists of similarity transformations and satisfies the open set condition then its attractor supports a self-similar measure with Hausdorff dimension equal to the similarity dimension. In this article we prove the following result which may be regarded as a form of partial converse: if an iterated function system consists of invertible affine transformations whose linear parts do not preserve a common invariant subspace, and its attractor supports a self-affine measure with Hausdorff dimension equal to the affinity dimension, then the system necessarily consists of similarity transformations. We obtain this result by showing that the equilibrium measures of an affine iterated function system are never Bernoulli measures unless the system either is reducible or consists of similarity transformations. The proof builds on earlier results in the thermodynamic formalism of affine iterated function systems due to Bochi, Feng, Käenmäki, Shmerkin and the first named author and also relies on the work of Benoist on the spectral properties of Zariski-dense subsemigroups of reductive linear groups.
The Furstenberg set and its random version
Authors: Fan Aihua , Queffélec Hervé , Queffélec Martine
Published: November 2022

We study some number-theoretic, ergodic and harmonic analysis properties of the Furstenberg set of integers

S={\{2^{j}3^{k}\}}

and compare them to those of its random analogue

T

. In this half-expository work, we show for example that

S

is “Khinchin distributed”, is far from being Hartman uniformly distributed while

T

is, also that

S

is a

\Lambda(p)

-set for all

2<p<\infty

and that

T

is a

p

-Rider set for all

p

such that

4/3<p<2

. Measure-theoretic and probabilistic techniques, notably martingales, play an important role in this work.
A note on the real support of Silva–Hasumi–Morimoto ultrahyperfunctions
Authors: Alves Magno B. , Franco Daniel H. T.
Published: November 2022

Recently, we have studied the relation between the singular spectrum of a class of tempered ultrahyperfunctions corresponding to proper convex cones and their expressions as boundary values of holomorphic functions. In this note, we added some more results on the singular spectrum of the tempered ultrahyperfunctions. More specifically, the “microlocalization” of a Silva–Hasumi–Morimoto ultrahyperfunction corresponding to an open proper convex cone is addressed. Following Nishiwada’s approach to the analytic wave front set, we introduce the real singular spectrum of such an ultrahyperfunction and prove that it canonically projects onto Silva’s real support.
Extravascular lung water index, pulmonary vascular permeability index, and global end-diastolic volume index in mechanically ventilated COVID-19 patients requiring prone position ventilation: a preliminary retrospective study
Authors: De Rosa Rosanna Carmela , Romanelli Antonio , Gallifuoco Michele , Messina Giovanni , Di Costanzo Marianne , Corcione Antonio
Published: November 2022

Background: There is a lack of data on extravascular lung water index (EVLWi), pulmonary vascular permeability index (PVPi), and global end-diastolic volume index (GEDVi) during prone position ventilation (PPV) in coronavirus disease 2019 (COVID-19) patients. The objectives of this study were to analyze trends in EVLWi, PVPi, and GEDVi during PPV and the relationships between these parameters and PaO2/FiO2.Methods: In this preliminary retrospective observational study, we performed transpulmonary thermodilution (TPTD) in seven mechanically ventilated COVID-19 patients without cardiac and pulmonary comorbidities requiring PPV for 18 hours, at specific times (30 minutes pre-PPV, 18 hours after PPV, and 3 hours after supination). EVLWi, PVPi and GEDVi were measured. The relationships between PaO2/FiO2 and EVLWi, and PVPi and GEDVi values, in the supine position were analyzed by linear regression. Correlation and determination coefficients were calculated.Results: EVLWi was significantly different between three time points (analysis of variance, P=0.004). After 18 hours in PPV, EVLWi was lower compared with values before PPV (12.70.9 ml kg–1 vs. 15.31.5 ml kg–1, P=0.002). Linear regression showed that only EVLWi was correlated with PaO2/FiO2 (β =–5.757; 95% confidence interval, –10.835 to –0.679; r=–0.58; R2=0.34; F-test P=0.029).Conclusions: EVLWi was significantly reduced after 18 hours in PPV and values measured in supine positions were correlated with PaO2/FiO2. This relationship can help clinicians discriminate whether deterioration in gas exchange is related to fluid overload or disease progression. Further clinical research should evaluate the role of TPTD parameters as markers to stratify disease severity and guide clinical management.
Pastoral care for Gender-based violence affected South African University students
Authors: Makhanya The Rt. Revd Monument Thulani Bongani
Published: November 2022

Gender-based violence is a widespread type of human rights violation that frequently takes place in academic environments like schools and universities. The prevalence of genderbased violence (GBV) among university students is shockingly high. Many survivors of campus sexual abuse experience academic difficulties in addition to the emotional and psychological impacts of the assault, which in some cases may necessitate them taking a leave of absence or even dropping out of school altogether. Many students entering South African HEIs would have already been exposed to or experienced violence because of South Africa's alarmingly high rate of sexual assault against children. GBV in Universities, has many causal factors, including age, societal norms, masculinity, and social media. This paper utilized secondary data as a methodology to collect data. This paper proposes that universities combine the assistance of psychologists and pastoral caregivers in the healing of those affected by GBV, because people who have experienced GBV may benefit from pastoral counselling in focusing their attention on finding purpose and meaning in their lives despite adversity.
The role of the international institutions in the protection of human rights and freedoms in the sphere of national security
Authors: Svoboda Ivo , Epel Oksana , Suleimanova Susanna , Ievenko Dmytro , Kovalova Olha
Published: November 2022

The need for qualitative changes in the field of national security also requires the transformation of international institutions responsible for the protection of human rights and freedoms. Therefore, the aim of the article was to identify the role of international institutions in the protection of human rights and freedoms in the field of national security. The main methodological tools were the observational method and the comparative legal method. There is currently a dynamic increase in the number of international treaties ratified in the field of human rights. International institutions are making many efforts to achieve the highest level of efficiency of adequate protection mechanisms. The authorization of an illegal war exposes states to prosecution in international courts. Everything leads to the conclusion that the competence capacity of institutions seems to be limited in the face of increasing violations of human rights in many regions of the world, which leads to the need to reform international legal instruments and relevant procedures for the protection of human rights and freedoms in the field of national security.
DEVELOPMENT OF HIGH ENERGY AND FUEL ECONOMY CERAMIC INSULATED BIOMASS MULTI COOKING SYSTEM
Authors: EKPUNOBI U. E. , ONYENZE C. C. , AGBO S. C. , UMENNADI P. , IFEAGWU O. B.
Published: November 2022

The analysis of Inyi clay and its utilization in the production of an improved cook-stove is significant to the existence of mankind and his community. This study was carried out to analyse the mixture of clay, cassava peel and grog and its utilization in the production of an improved cook-stove. The clay deposits were collected from Inyi Local Government, Enugu State. Different ratios of the mixture was used in the following percentage proportions by weight of clay to cassava peel to grog: A (40:40:20), B (40:30:30), C (40:20:40), D (40:10:50) at firing temperatures 900oC and 1000oC. The physical analysis (apparent porosity, linear shrinkage, dry-fired shrinkage, total shrinkage, bulk density, water absorption and percentage making moisture) was carried out using rectangular shape test piece to ascertain the feasibility in the lightweight stove production, the strength and the durability of products. The chemical analysis (xrd and xrf) was carried out using x-ray diffractometer and x-ray fluorescence in order to determine their crystallographic parameters and elemental composition respectively. The morphological analysis (SEM) was carried out using the scanning electrode microscope to obtain the resolutions and magnifications. The addition of cassava peel and grog was found to have great effect on the insulating properties (shrinkage, bulk density, apparent porosity and water absorption) of the clay. Chemical analysis revealed SiO2 (45.26%) and Al2O3 (35.19%) as major constituent. The result of this study showed that cassava peel was suitable in enhancing the insulating properties of Inyi clay and can be utilized to induce insulation in clay minerals when desired.
Ekoloji Felsefesinin İnsanmerkezciliğe Eleştirisi
Authors: ÇEPİK Rabia
Published: November 2022

Ekoloji felsefesi farklı ideolojiler veya kuramlar tarafından farklı terimler ile ve farklı önceliklerle ortaya konulmaktadır. Bu çalışmada, bazı ideoloji ve kuramların ekolojiye genel olarak nasıl yaklaştığı ortaya konulduktan sonra, bunlardaki insanmerkezcilik incelenecektir. Bu anlamda çalışmada incelenecek kuramlar; faşist ekoloji, Marksist ekoloji, anarşist ekoloji ve Leopard’ın toprak etiği kuramlarıdır. Bu kuramlardan biri olan faşist ekoloji, insanmerkezci hatta ırkçı iken diğer birçoğu insanmerkezcilikten kurtulmadan ekolojik sorunların çözülemeyeceğine vurgu yapmaktadır. Sonuçta bu farklı ideoloji ve kuramların bakış açısı incelenerek doğaya insanmerkezci olmayan bir şekilde yaklaşmak gerektiği ve bunun yolu ortaya konulmaya çalışılacaktır. Çünkü insanmerkezli bakış açıları ile doğaya yaklaşmak şimdiye kadar ekolojik problemlere vadettiği çözümü sunamamıştır.
O PERFIL DO LEITOR NOS LIVROS BRASILEIROS DE ENSINO DE LITERATURA DA DÉCADA DE 2010
Authors: Mossi de Quadros Camila , Hisae Yaegashi Zaponne Mirian
Published: November 2022

Este artigo apresenta um recorte da tese intitulada O ensino de literatura em livros brasileiros (entredécadas 1960-2010) que identificou e analisou 28 livros que tematizavam o ensino de literatura e que foram publicados por autores brasileiros nesse período. As obras foram analisadas, cotejadas entre si e com os documentos educacionais, objetivando a definição de alguns aspectos relacionados ao ensino de literatura, dentre eles, do perfil do leitor predominante em cada década. Os resultados evidenciaram que as obras se antecedem à legislação brasileira sobre o tema, pois, em síntese, parte-se de um perfil de leitor humanizado (moralizado), nas décadas de 1960/1970, para um leitor emancipado na década. de 1980. O presente artigo apresenta o perfil do leitor que se configurou nos livros na década de 2010 a 2020. Neste período, há a progressiva supressão do perfil de leitor literário como aquele que se engaja socialmente, em direção à formação de um leitor fruidor, conceito que se consolida na década de 2010 e se reflete nos documentos legais, sendo adotado pela BNCC, em 2018, como objetivo da formação do leitor.
COST AND BENEFIT ANALYSIS OF HEALTHY RICE PRODUCTION COMPARING WITH OTHER RICE IN UPPER NORTHERN OF THAILAND
Authors: Phaoumnuaywit Aussawin , Cheamuangphan Aree , Sinhavara Montri
Published: November 2022

This research aims to examine rice production costs and returns as well as to focus on reducing inputs used by farmers who plant healthy rice and other rice. By studying the optimal use of agricultural inputs, excessive inputs are used to create a model of expected cost and return in terms of the budgeting analysis. The samples of farmer were selected by purposive sampling from 900 farmers. The research result showed that, the average net return of rice farmers was lower than that of healthy rice farmers at all levels of efficiency. The highest average return was obtained from rice farmers with high efficiency at 4,296.92 Baht per Rai. When the excess factor is adjusted in accordance with the performance analysis, the net return is higher. The most effective rice growers were farmers at the level of 7,170.76 Baht / Rai. The number of laborers was statistically.
MEASURING THE TAX REVENUE AND TAX BASE EROSION; EVIDENCE FROM TAIWAN
Authors: Wang Yu kun
Published: November 2022

Basically, tax evasion is a gamble taken by private agents and limited “public-sector”. It is rather difficult to get accurate information about the extent of underground economy activities in the goods and labour market, because all individuals engaged in those activities wish not to be identified. Undoubtedly, engaging in the research can be considered as a scientific passion for knowing the unknown. To explore the relationship among economic growth, tax rate, debt, consumer price index and tax revenue. This study differs from the traditional methodology. We adopt SUR-OLS method and Threshold approach for estimating the response of economic growth on total tax revenue,direct tax revenue and indirect tax revenue in Taiwan from 1991-2020. This paper further discusses the response of total tax, direct tax and indirect tax to the fluctuation of tax rate. We show that as the tax rate is between 12.59% and 13%, the increase of income leads to the decrease instead of the increase for direct tax revenue, resulting in serious tax base erosion. That is, the relationship between GDP and TTR presents a Nshaped relationship. However, indirect tax does not exist any tax rate threshold effect, On the other hand, with the increase of GDP, indirect tax revenue also increases.
Fibromatosis ligamentoide mesentérica
Authors: García Yllán Verónica , Checa Peña María de Jesús , Rey Nodar Severino
Published: November 2022

La fibromatosis ligamentoide (fibromatosis invasiva, fibroma desmoide) es una neoplasia mesenquimatosa, intermedia entre los tumores benignos y malignos, de origen fibroso, que de manera infrecuente puede afectar el mesenterio. Se presenta el caso de un paciente masculino con tumoración fibrosa intraabdominal a nivel de raíz de mesenterio. Se realiza una revisión de la literatura.
Linfadenitis axilar por silicona. Presentación de un caso diagnosticado por punción aspiración con aguja fina
Authors: Pérez López Albadio Samir , López Soto María Victoria , Álvarez Santana Reynaldo
Published: November 2022

La linfadenopatía por silicona es una rara complicación en pacientes con implantes mamarios, a menudo es confundida con tumores primarios o secundarios. Se trata de una paciente femenina de 42 años, con implantes mamarios desde hace 12 años, que consulta por presentar dolor y aumento de volumen axilar bilateral. Se realizó ultrasonido, mamografía y punción aspiración con aguja fina, donde se apreciaron: histiocitos y células gigantes fagocitando las partículas de silicona, entremezclada con linfocitos. Hicieron explante de las prótesis y vaciamiento axilar del primer nivel bilateral. El caso reportado evidencia la utilidad de la punción aspiración con aguja fina como herramienta para el diagnóstico diferencial de adenopatías axilares en pacientes con prótesis mamarias.
Eficacia de la teledermatología en la reducción del índice de breslow en el melanoma cutáneo
Authors: Cayuela Espí José Vicente , Sánchez Gutiérrez David , Alarcón Soldevilla Fernando , Ortiz Reina Sebastián , Ruiz Merino Guadalupe
Published: November 2022

La teledermatología (TD) permite al médico de Atención Primaria hacer una consulta telemática al dermatólogo, adjuntando una breve descripción del caso junto a una o varias imágenes de la lesión. Nos planteamos si los melanomas derivados por vía TD presentaban un Breslow menor que los valorados por la vía convencional; dicho de otro modo, si esta herramienta permitía detectar de forma más veloz las lesiones melánicas malignas. Como objetivos secundarios, queríamos determinar si el proceso asistencial del paciente se veía acelerado por esta vía.Nuestros resultados determinaron que la profundidad de los melanomas derivados por la vía TD presentaban casi la mitad de la dimensión de aquellos derivados por vía convencional y, también, que la demora asistencial se vio reducida en este grupo.Por tanto, consideramos que estamos ante una herramienta que nos puede permitir diagnosticar melanomas en fases más iniciales, así como agilizar la lista de espera.
Related to the Problem of Word Formation in German
Authors: Jurayev Tuychi
Published: November 2022

The problem of word production, together with its many models, forms, and styles of expression. This article investigates the challenges surrounding the development of words in German, as well as the viewpoints of a number of scientists who have dealt with these topics. Concurrently, the categorization of these things in accordance with the semantic principle is being spoken about as well.
Pengaruh Perhatian Orang Tua Terhadap Hasil Belajar Matematika
Authors: Sianipar Rama Uli , Sidabutar Ropinus , Siregar Golda Novatrasio Sauduran
Published: November 2022

Tujuan dari penelitian ini untuk mengetahui apakah terdapat pengaruh perhatian orang tua terhadap hasil belajar matematika siswa. Penelitian ini menggunakan pendekatan kuantitatif. Jenis penelitian yang digunakan pada penelitian ini adalah ex post facto. Penelitian ex post facto menurut Kerlinger (dalam Danuri & Siti, 2019) adalah penyelidikan empiris yang sistematis dimana peneliti tidak mengendalikan variabel bebas secara langsung, karena variabel tersebut pada dasarnya memang tidak dapat dimanipulasi. Populasi pada penelitian ini adalah seluruh siswa kelas XI SMA Negeri 4 Pematangsiantar tahun pelajaran 2022/2023 sebanyak 355 siswa. Pada pengambilan sampel peneliti menggunakan cluster random sampling pada penelitian ini peneliti mengambil dua kelas yaitu XI PMIA 1 dan kelas XI PMIA 2, jadi total sampel pada penelitian ini berjumlah 70 siswa. Instrumen yang digunakan yaitu angket dengan 30 pernyataan tertutup, dengan menggunakan pengukuran skala likert. Setelah dilakukan uji prasyarat, di peroleh kesimpulan bahwa perhatian orang tua berpengaruh secara positif dan signifikan terhadap hasil belajar matematika siswa. Dibuktikan dari perhitungan analisis regresi linearitas sederhana dengan  nilai  dengan tingkat signifikansi 0,00 < 0,005. Sehingga H0 ditolak dan Ha diterima. Pengaruh perhatian orang tua terhadap hasil belajar matematika siswa di kelas XI SMA Negeri 4 Pematangsiantar adalah berpengaruh sebesar 76% dan sisanya dapat dipengaruhi oleh faktor yang lain seperti, motivasi belajar, minat belajar, dll.
Generic Adaptive Emergency Agile Model for Health care and Pharmaceuticals in crisis situation
Authors: Gunjan Behl  , Deepali Shahane  , Baljeet Kaur  , Shambhu Rai
Published: November 2022

Pandemic challenges demanded immediate solutions and continues improvement in solutions on field which motivated the entire world’s research community to find an opportunity to provide speedy solutions to problems. Agile developments provide immediate improvements which functioned on the grounds of assorted health care units, medical facilities, pharmaceuticals and variants of COVID 19 cases. Agile developments proved its effectiveness for immediate solutions which take full advantage of aids to health and pharmaceutical organizations and also exploits worth rapport with health stakeholders. This springs a thirst for carrying out the study on agile developments and its effectiveness for health and pharmaceuticals so, the study focuses to design generic adaptive emergency agile model for Health care and pharmaceuticals to deal with Crisis pressure which will support COVID 19 medical research field.
Study of specific properties of Polygonum Aviculare L. dry extract as a hemostatic agent
Authors: Feruza Saydalieva  , Ziyoda Fayzieva  , Bahtigul Azimova  , Nodirali Normakhamatov
Published: November 2022

Polygonum aviculare L., has been used in traditional medicine for many years. Hemostatic activity of the Polygonum aviculare L. dry extract (PADE) on the duration and amount of bleeding was studied in the current research. Moreover, the effect of the PADE was investigated on platelet count and capillary permeability. The results showed that the PADE administration increased platelet count by 212%, decreased retraction time by 50% and increased adhesive capacity by 225% and significantly reduced capillary permeability in the experimental animals. According to the results of this experiment, the Polygonum aviculare L. dry extract can be recommended to use in medical practice as a hemostatic agent in various hemorrhages.
IoT BASED SECURED HEALTHCARE USING 6G TECHNOLOGY AND DEEP LEARNING TECHNIQUES
Authors: Chirag Singh  , Mallesha M  , M. Vijayaragavan  , J. SURESHBABU  , Deema mohammed alsekait
Published: November 2022

From 2040 forward, the entire healthcare industry will be dominated by the 6G communication revolution. It will control the whole medical industry in addition to numerous other fields. Medical services will be totally dependent on artificial intelligence and 6G communication technology, which will alter our perception of the way of life. Right now, reality presents the main impediments to clinical consideration, and 6G means to kill these obstructions. Similarly, 6G will be presented as a game-changing technology for medical services. In light of this, we foresee the healthcare system for the era of 6G communication technology. In this paper, we talk about the reception of AI with the Internet of Things (IoT) in the medical services framework and its effect on a few clinical fields.
GAMIFICAÇÃO PARA TRATAMENTO DE DISTÚRBIOS VISUAIS, O VILÃO SE TORNA HERÓI
Authors: Passos Santos Aline , Sonoda Rodrigo Trentin
Published: November 2022

A tecnologia proporciona diversas possibilidades e pelo seu acesso simples as pessoas aderiram de forma acentuada ao seu uso. De modo que isto trouxe consigo algumas consequências, especialmente para a visão, pelo excesso de tempo de uso das telas e games. Existe uma considerável parte da população que utiliza aparelhos eletrônicos intensamente para realizar suas tarefas diárias, seja para se relacionar com outras pessoas, para trabalhar com diversos tipos de telas. Essa utilização pode se tornar exacerbada e ocasionar alguns malefícios devido a exposição a luz azul, tais como fadiga ocular, sedentarismo, alteração no ciclo circadiano e o uso exagerado da acomodação, ocasionando estresse e fadiga ocular. A tecnologia pode proporcionar benefícios, podendo contribuir para tratamentos de distúrbios visuais, utilizando o ambiente virtual, ou ainda servindo de ferramenta para documentar as disfunções, objetivando-se de maneira não invasiva melhorar a visão binocular e acuidade visual de forma mais atrativa e interessante que os métodos tradicionais. Através de pesquisas bibliográficas e publicações indexadas nas plataformas Scielo, PubMed e Google Acadêmico, demonstra-se a importância de pesquisas sobre a manutenção e reabilitação de saúde visual.
MANUAL EDUCATIVO COMO ESTRATÉGIA DE FACILITAÇÃO DA COMUNICAÇÃO ENTRE OS DIVERSOS ATORES DOS SERVIÇOS DE SAÚDE: PROTOCOLO DE REVISÃO DE ESCOPO
Authors: Alves de Abreu Luiz Onete
Published: November 2022

Este trabalho tem como objetivo a construção de protocolo de revisão de escopo visando mapear evidências científicas na literatura sobre a utilização de manual educativo na facilitação da comunicação nos serviços de saúde. Se apresenta na forma de protocolo de pesquisa embasado em recomendações do JBI manual for evidence synthesis, do Joanna Briggs Institute, também seguindo o PRISMA- ScR (Preferred Reporting Items for Meta-Analyses- Extension for Scoping Reviews). A busca, junto da coleta de dados, será efetivada baseada nos DeCS/MeSH (Descritores em Ciências da Saúde, Medical Subject Headings). De antemão, a revisão será registrada na plataforma Open Science Framework (OSF). Como critérios de inclusão, serão consideradas produções científicas publicadas que tenham: existência de evidências científicas (problema), uso de manual educativo (variáveis do estudo), e facilita a comunicação (resultados alcançados). Serão consideradas fontes as seguintes bases de dados: Medline, Lilacs, Scielo. A etapa de síntese e posterior discussão dos resultados será empreendida aplicando a técnica de Análise de Conteúdo, de Laurence Bardin.
Acoustic Analysis of Voicing Contrast in Malay Word-Initial Plosives Produced by Mandarin-Speaking Children
Authors: Abdul Hamid Badrulzaman , Yee Chong Jin , Mohd Ibrahim Hasherah
Published: November 2022

Voice Onset Time (VOT) is an acoustic measure widely used to measure the characteristics of plosives across various languages. This study investigates the acquisition of voicing contrast in Malay word-initial plosives produced by Mandarin-speaking children. Fifteen subjects between the ages of 3;00 to 7 and 11 were recruited. The children completed a picture-naming task, and the speech samples were audio-recorded and analyzed using PRAAT. Descriptive VOT values (ms) across ages were presented and compared to previous normative findings. Results revealed that children aged 3;00 produced only a short lag, while children aged 4;00 to 6;00 produced short lag-long lag contrast, which is not similar to the expected VOT pattern of Malay plosives. Additionally, with increasing age, children acquired adult-like VOT productions. The VOT distributions follow the developmental path proposed for languages with two-way contracts. This finding is the first VOT data on Malay word-initial plosives by Mandarin-speaking children. Maturity of motor development and coordination, as well as cross-linguistic exposure, influenced productions. Thus, further studies examining cross-linguistic influence, particularly controlling for the duration of exposure to L2 in multilingual language acquisition with a larger sample size, are warranted to validate the findings from this study.
The Holocaust and the Chahi Taret Khuntakpa: A Critical Comparison
Authors: Ashangbam Arundhati , Mangang Paonam Sudeep
Published: November 2022

Genocides have become an indelible scar in the history of humankind. These dark historical episodes epitomise power struggles between races and the perils of group identification. One such episode considered a unique occurrence in human civilisation is the Holocaust (1940-1945). Another seemingly forgotten historical episode is the Chahi Taret Khuntakpa or the Seven Years’ Devastation. It took place in the land of Poirei, now known as the state of Manipur, located in the northeastern part of India. The Seven Years’ Devastation refers to the atrocities committed by the Burmese against the Meitei civilisation from 1819 to 1826. This event, which led to the signing of the Yandabo Treaty of 1826, found a prominent place in the history of Southeast Asia. This paper examines the striking similarities and the cause of genocide between the Seven Years’ Devastation and the Holocaust. Moreover, the paper also studies the effects of violence in the Seven Years’ Devastation and the Holocaust.
The Impact of L2 Vocabulary Knowledge on Language Fluency
Authors: Tong Yanli , Hasim Zuwati , Abdul Halim Huzaina
Published: November 2022

While there has been ample research on the relationship between vocabulary knowledge (breadth and depth aspects) and speaking proficiency, very little attention has been given to the correlation between the four aspects of L2 lexical knowledge (receptive/productive/breadth/depth) and L2 speaking ability, and none has focused on the moderation effect of L2 vocabulary fluency in speaking capability. The current research recruited 312 Chinese university students as participants. It used the Structure Equation Model (SEM) to assess the relative effectiveness of the four aspects of L2 lexical knowledge and the predictive power of the overall L2 lexical knowledge in L2 speaking. It also ascertained the moderation effect of L2 vocabulary fluency by using Ping’s Single Product Indication Method. Results showed that of the four aspects of L2 vocabulary knowledge, productive vocabulary depth contributed the most to speaking skills. The productive vocabulary breadth ranked second, with receptive vocabulary breadth and depth showing less contribution to speaking proficiency. Regression analyses indicated that overall L2 lexical knowledge explained 47% of the variance in speaking. On the basis of these research findings, educational implications are further discussed, then limitations are identified.
Expression and in silico Analysis of CIDRα1 Recombinant Protein from Plasmodium Falciparum as a Malaria Subunit Vaccine Candidate
Authors: Sulistyaningsih Erma , Istinaroh Nurul , Dewi Rosita , Hairrudin Hairrudin
Published: November 2022

Malaria vaccination is an essential approach to combat malaria. One major protein studied for vaccine development is Plasmodium falciparum erythrocyte membrane protein-1 (PfEMP1). It contains several important domains for malaria pathogenesis. The binding of Cysteine-rich interdomain region α1 (CIDRα1) of PfEMP1 to endothelial protein C receptor (EPCR) is associated with cerebral malaria, while CIDRα1 binding to CD36 has been correlated with uncomplicated malaria. The vital function of CIDRα1 of PfEMP1 makes it a potential vaccine candidate to prevent clinical features of malaria. A long journey of vaccine development can be shortened by the advancement of bioinformatics and biotechnology techniques. This study aimed to express the recombinant CIDRα1 of PfEMP1 and investigate its potency as a malaria subunit vaccine candidate by in silico analysis. Constructed CIDRα1-PfEMP1 was expressed in E. coli BL21(DE3) after induction with Isopropyl ß-D-1-thiogalactopyranoside (IPTG) and purified using Ni-NTA column. In silico analysis on CIDRα1 of PfEMP1 sequence was conducted using ProtParam Tool for its physicochemical properties, Iterative Threading ASSEmbly Refinement (I-TASSER) server and JPred4 program to predict secondary structure, 3D modelling, and ligand-binding site, BepiPred 2.0 and Kolaskar-Tangaonkar to predict B-cell epitope, NetCTL server to determine T-cell epitope, and Vaxijen v2.0 server to predict its antigenicity. The chimeric CIDRα1 of PfEMP1 protein had a 27 kDa molecular weight and was classified as a stable protein. The secondary structure consisted of 6 helices connected with loops. It revealed similarity to CD36-binding protein, EPCR-binding domain, and protein involved in rosetting. The 3D structure modelling demonstrated conserved ligand-binding sites and accessible surface area, which are vital for receptor binding. It had B-cell and T-cell epitopes and was non-allergenic. The properties of the chimeric CIDRα of PfEMP1 indicated its potential as a malaria subunit vaccine candidate.
HIGHLIGHTS

The binding capacity of CIDRα1 of PfEMP1 to endothelial protein C receptor (EPCR) and CD36 makes it a potential vaccine candidate to prevent clinical malaria
The chimeric CIDRα1 of PfEMP1 protein was a stable protein and showed similarity to CD36-binding protein, EPCR-binding domain, and protein involved in rosetting, which demonstrated conserved ligand-binding sites and accessible surface area, which are vital for receptor binding
The chimeric CIDRα1 of PfEMP1 protein had B-cell and T-cell epitopes and was non-allergenic in in silico analysis, indicating its potential as a malaria vaccine candidate

GRAPHICAL ABSTRACT
An Important Stage in the Development Process of the “Patient Safety Education Program”: Needs Assessment (A Qualitative Study)
Authors: ÖTÜN Tuba , AKÇİN ŞENYUVA Emine
Published: November 2022

Introduction: It is important to recognize the needs of nurses in order to develop their knowledge and skills about patient safety and to create an education program.Aim: The study aims to recognize the needs of nurses in order to form a basis for structuring the “Patient Safety Education Program” based on the Constructivist Learning Model.Method: The study is designed as a qualitative study. The participants were randomly reached. The data were collected by using a semi-structured interview form.Results: The results of the study show that nurses are intertwined with patient safety in all fields of care. When structuring education programs related to patient safety, it is necessary to select subjects, teaching methods, materials, and assessment methods that will improve nurses' knowledge and skills related to patient safety.Conclusion: In accordance with these results, it can be recommended to use the study results when structuring formal educational programs.
Armas, prensa y política en la Córdoba de la década de 1880
Authors: Goycoechea Enrique de
Published: November 2022

Los objetivos del artículo son, por un lado, visibilizar algunas características de la prensa política cordobesa de la década de 1880, un ámbito clave donde se expresó el desacuerdo y la lucha política en aquellos años, mientras que, por otro, identificar a sus protagonistas y la función que cumplieron parte de ellos durante los años centrales del régimen oligárquico nacional. Respecto a los resultados, los mismos dan cuenta no solo de la relevancia que adquirió la prensa como herramienta indispensable en distintos planos de la lucha política, sino también de la activa participación de muchos de sus miembros en la arena política cordobesa, la cual tuvo como corolario el desplazamiento del poder para algunos, y la forja de sólidas vinculaciones en el plano político nacional para otros.
Understanding Initiation and Evolution of Pitting Corrosion in 7075-T6 Aluminum Alloy by Four-Dimensional X-Ray Microtomography
Authors: Sinclair Daniel , Niverty Sridhar , Chawla Nikhilesh
Published: November 2022

X-ray microcomputed tomography was conducted on an AA7075-T651 sample immersed in a 3.5 wt% NaCl solution to provide time-resolved measurements of localized corrosion. A nondestructive, volumetric analysis of pitting sites and local microstructural features followed, and quantitative results were combined with 2D and 3D visualizations. During alternating immersion periods, pitting was initiated at cathodic intermetallic inclusions and continued throughout the study. Rates of pit growth varied as a response to the decoupling of inclusions from the matrix, resulting in a start-and-stop trend that was observed in a significant number of examined sites. When a sample with a higher extent of cold rolling was examined with the same procedure, a finer and more homogeneous distribution of inclusions correlated with an increase in the maximum and mean pit depth. This change was attributed to the more frequent exposure of subsurface inclusions by localized corrosion, a phenomenon that mitigated the passivating effect of decoupling. Additionally, the effects of continuous immersion vs. alternate immersion were examined for metallurgically identical samples. Intermittent drying during the alternate immersion period destabilized the passive layer, increasing mean pit depth, while continuous immersion for 20 d produced a uniform and protective layer of corrosion product.
Análise de estudos recentes sobre a formação de professores alfabetizadores com a leitura e com a contação de histórias
Authors: Feitoza Iranara Saraiva Alves , Souza Angela Maria Baltieri , Sousa Clarilza  Prado de
Published: November 2022

Ler e contar histórias são proposições fundamentais para o processo de alfabetização e configuram-se como premissas iniciais nas formações oferecidas a professores alfabetizadores nos últimos anos. Neste contexto, torna-se relevante a discussão com respeito às divergências em torno das preferências entre as concepções e as metodologias que fundamentam as práticas docentes, em especial nos primeiros anos escolares. Com a finalidade de identificar os estudos recentes acerca desta temática, mais especificamente entre os anos de 2010 a 2020, a presente pesquisa utiliza-se do software Iramuteq para a categorização dos resultados e para a análise do conteúdo dos estudos recentes em torno desse assunto. Os resultados apresentados sinalizam a necessidade de investir na formação leitora oferecida inicialmente aos professores e consequentemente aos educandos, pois muitas vezes o planejamento escolar minimiza os objetivos de leitura em torno de correções ortográficas ou de uma escolarização literária. Embora esses propósitos didáticos tenham sua importância, pensar a alfabetização pela perspectiva do letramento consiste na valorização da função social das práticas de leitura e na sistematização das ações pedagógicas pelos professores alfabetizadores. Portanto, alfabetizar e letrar (COSSON, 2014; SOARES, 2004) incide na compreensão das problemáticas reais pela escola e no diálogo que mobiliza os diferentes textos a distintos propósitos comunicativos.
Effect of temperature and pH on keratinophilic fungus Chrysosporium indicum in vitro conditions
Authors: Srivastava Naina
Published: November 2022

Hyphomycetes includes keratinophilic, dermatophytes and non dermatophytes filamentous fungi. Keratinophilic fungi growth is effected by biotic and environmental factors. Evaluation of effect of pH and temperature as physical conditions was observed . In the present investigation the steps have been undertaken to study the effect of temperature and Ph on keratinophilic fungus Chrysosporium indicum in vitro condition. The study of fungus has specific range of favourable pH and temperature. The normal growth of chrysoporium inducing was observed between 250C to 350C, where maximum growth and speculation was observed at 30. There has been a drastic reduction in fungal growth below 100C or 150C and speculation and growth declined at above 350C. So, it is observed that between 25 0C to 350C fungal growth and sporulation occur favorably .Below 100C and above 350C did not favour the growth and reproduction of keratinophilic fungi. Effect of hydrogen ion concentration was observed particularly for Chrysosporium indicum. Favourable hydrogen ion concentration for mycelial growth was 7.00. In present study Chrysosporium indicum fungal hyphae growth was changed with pH and the maximum growth was found at the end of incubation day is about pH 7 to 7.5
Production of plant growth substances by asymbiotic nitrogen fixers
Authors: Krishna Vandna
Published: November 2022

Modern agriculture faces challenges such as loss of soil fertility fluctuating climatic factors and increase in pathogen and pest attacks. The sustainability and environmental safety in agriculture production needs eco-friendly approach like use of biofertilizers, bio pesticide and green manuring etc. The multiple beneficial effects of microbial inoculants apart of nitrogen fixation needs further research and their use in modern agriculture. This review summarises the plant growth substances related research and its benefits from asymbiotic bacteria.
Initiation of the establishment of a technology business incubator at university for agripreneurship (study case at Bengkulu University, Indonesia)
Authors: Novanda Ridha Rizki
Published: November 2022

Purpose. This paper aims to analyze aspects related to the establishment of business incubators at Bengkulu University as well as what factors are most expected by students towards the establishment of technology business incubators at this university.

Results. The results of data collection were processed using the partial least square method to analyze aspects related to the establishment of business incubators at Bengkulu University as well as factors are most expected by students towards the formation of technology business incubators at this university. This research show that support variables were found had a significant effect on the initiation of the Technology Business Incubator at Bengkulu University. Support is providing research and business development assistance and access to technology used for students in agripreneurship. Support is the latent variable requested by five manifest variables: (1) access partnership programs from the ministry, (2) professional network access, (3) technology access, (4) access international relations, and (5) job creation.

Scientific novelty. Support variables were found had a significant effect on the initiation of the Technology Business Incubator at Bengkulu University. This research explains a lot about the novelty of the type of establishment of pilot incubators in universities in poor areas.

Practical value. The results are useful in initiating the creation of a business incubator that meets the requirements. The results of this study can be used as a reference in establishing a business incubator at the university level. It is important to ensure access to funding, to professional services, to technology, to international relations, and an understanding of the importance of creating jobs.