bluuebunny/crossref_metadata_2025 huggingface dataset:
The Impact of Hookah Smoking on AMH Levels in Women: A Pilot Study
Authors: Albeitawi Soha Nafez , Obeidat Rawan Ahmad , Al-Mehaisen Lama Munther , Shehab Qasem Jamil , Elisabetta Garavaglia , Khamees Almu’atasim
Published: February 2023

Purpose:

Hookah (water pipe) smoking, an ancient tobacco smoking method, is gaining
widespread popularity worldwide. Although research in this field is still lacking, its harmful effect on
human health through the increased risk of cardiovascular disease, infection, and cancer has been
proven. Cigarette smoking has been found to have a detrimental effect on reproductive function. However,
data about the effect of hookah smoking on human fertility or reproductive outcomes are scarce.
In this study, we aimed to determine if smoking hookah has a harmful effect on the human ovarian reserve
test, anti-Mullerian hormone levels, and cycle regularity.

Materials and Methods:

A total of 100 healthy non-cigarette smoking women in the 25-35 age range
undergoing laboratory investigations were randomly chosen to participate. After obtaining consent,
they completed a questionnaire about smoking habits and menstrual data. Blood samples were withdrawn
for anti-Mullerian hormone testing. The anti-Mullerian hormone levels of 50 women hookahonly
smokers were compared to 50 non-smoking women.

Results:

There were no significant differences in mean anti-Mullerian hormone levels and cycle regularity
between hookah smokers and non-smokers. However, period pain was significantly associated
with hookah smokers relative to non-smokers (p = 0.036). There was an inverse relationship between
log10 anti-Mullerian hormone levels and log10 hookah smoking index. This correlation was significant
as measured by Spearman’s rho test, and the correlation coefficient was -0.331 and p-value =
0.02. Moreover, binary logistic regression for cycle regularity showed that hookah smoking was associated
with an increase in the likelihood of having an irregular cycle, but the effect was not significant
(p = 0.514) for hookah smoking.

Conclusion:

Under the conditions of this study, no significant association between hookah smoking
and neither AMH levels nor cycle regularity could be observed.
Value of MRI T2 FLAIR Vascular Hyperintensities Combined with DWI
ASPECTS in Predicting the Prognosis of Acute Cerebral Infarction with
Endovascular Treatment
Authors: Tao Zhonghai , Zhou Fang , Zhang Haojiang , Qian Mingyue
Published: February 2023

Objective:

To explore the MRI T2 fluid-attenuated inversion recovery (FLAIR) vascular
hyperintensities (FVH) combined with diffusion-weighted imaging (DWI) Alberta Stroke Program
Early CT Score (ASPECTS) in predicting the prognosis of acute cerebral infarction (ACI)
with endovascular treatment.

Methods:

The patients with ACI in the anterior circulation who underwent endovascular treatment
from June 2016 to December 2020 were divided into a good prognosis group and a poor prognosis
group according to the modified Rankin Scale (mRS) score at 90 days after the operation. The
differences in general clinical baseline data, CT-ASPECTS, FVH, and DWI-ASPECTS between
the two groups were analyzed. The receiver operating characteristic (ROC) curve was used to analyze
the predictive power of prediction models on prognosis.

Results:

The results of the Binomial Logistic regression equation showed initial National Institute
of Health stroke scale (NIHSS), Mori grade, DWI-ASPECTS, and FVH were independent risk
factors for prognosis. The predictive power of the FVH + DWI-ASPECTS prediction model was
highest, and the predictive power of DWI-ASPECTS was higher than that of CT-ASPECTS.

Conclusion:

DWI-ASPECTS is better than CT-ASPECTS in predicting the prognosis of ACI
with endovascular treatment, and the combined prediction model of FVH and DWI-ASPECTS
has higher prediction performance, which can be used as a preoperative evaluation method to predict
the effect of endovascular treatment for ACI.
INTERSECTIONS OF MASS MEDIA, TERRORISM, AND POLICY RESPONSE: HOW MASS MEDIATED REPRESENTATIONS OF TERRORISM MAY INFLUENCE COUNTERTERRORIST POLICIES
Authors: Nacos Brigitte
Published: February 2023

On November 22, 2022, Dr. Brigitte Nacos, Adjunct Professor of Political Science at Columbia University, presented Intersections of Mass Media, Terrorism, and Policy Response: How Mass Mediated Representations of Terrorism May Influence Counterterrorist Policies. The presentation was followed by a question-and-answer period with questions from the audience and CASIS Vancouver executives. The key points discussed were how the representation of terrorist attacks in mass media can influence public opinion and policy decisions. Several case studies were presented to illustrate this intersection.
 
Received: 2022-12-20Revised: 2022-12-29
STRENGTHENING ANALYSIS AND CRITICAL THINKING IN TIMES OF GEOPOLITICAL UNCERTAINTY
Authors: Pherson Randolph H.
Published: February 2023

On November 22, 2022, Randolph H. Pherson, Chief Executive Officer of Globalytica, presented on Strengthening Analysis and Critical Thinking in Times of Geopolitical Uncertainty. The key points discussed included emerging threats to intelligence and how to combat them with structured analytical techniques. The presentation was followed by a question-and-answer period with questions from the audience and CASIS Vancouver executives.
Received: 2023-01-03Revised: 2023-01-05
FRACTURES: THE IMPACT OF DISCORD, DISINFORMATION, AND DAMAGED DEMOCRACY
Authors: Orr Bueno Caroline
Published: February 2023

On November 23, 2022, Dr. Caroline Orr Bueno, Postdoctoral Research Associate at the University of Maryland, presented Fractures: The Impact of Discord, Disinformation, and Damaged Democracy. The key issues were the difficulty of defining and operationalizing disinformation, the major forms of extremist disinformation and what makes them effective to the human brain, and how disinformation was used by the 2022 Freedom Convoy.
 
Received: 2023-01-14Revised: 2023-01-17
MILITANT ACCELERATIONISM
Authors: Kriner Matt
Published: February 2023

On November 23, 2022, Mr. Matt Kriner, a Senior Research Scholar at Middlebury University's Center on Terrorism, Extremism, and Counterterrorism (CTEC) and Managing Director of the Accelerationism Research Consortium (ARC), presented on Militant Accelerationism. The key points discussed were militant accelerationism, its actors, and the strategies of accelerationist groups to pursue their goals of societal collapse.
 
Received: 2022-12-05Revised: 2022-12-21
MILITARY RESPONSES TO PRISON VIOLENCE IN LATIN AMERICA: A BIG MISTAKE OR A NECESSARY EVIL?
Authors: Godnick William
Published: February 2023

On November 25, 2022, Dr. William Godnick, Professor of Practice at the William J. Perry Center for Hemispheric Defense Studies, presented on Military Responses to Prison Violence in Latin America: A Big Mistake or a Necessary Evil? The presentation was followed by a question-and-answer period with questions from the audience and CASIS-Vancouver executives. The key points of discussion included the overpopulation of prisons in Latin America, how this can contribute to the reproduction of crime, a brief overview of prison riots in Latin America, and the interventions implemented to deal with these riots.
 
Received: 2022-12-05Revised: 2022-12-18
Nationalising Scorched Earth - Memory and Destruction of Monuments from Vukovar to Knin
Authors: Piasek Michał
Published: February 2023

Research has often focused on Croatian memorialisation processes in specific places like Bleiburg and Jasenovac, controversial places during and after World War II. This article employs another view and elaborates on the destruction and removal, as well as the recent restoration of monuments and reconstruction of sacred architecture. It examines current memory processes in places once in the Republic of Serbian Krajina (1991-1995), from Vukovar to Knin. It stresses the different roles between state-organised and private commemorations in these historically multi-ethnic and -religious areas. The paper addresses problems like the demolition of monuments not fitting into the state narrative and analyses various historical processes that instigated the (re-)use of revisionist and mostly politically tolerated symbols and inscriptions on monuments and sacred architecture. With attention to the latter, it specifically deals with the reconstruction of a Catholic and Christian-Orthodox church in the Lika region. The research connects historical and anthropological approaches and contributes to the interdisciplinary field of memory studies.
Protodiplomacy Across the Mediterranean: The Catalan Participation in the First Congresses of Byzantine Studies in South Eastern Europe During the Interwar Period
Authors: Mallart Lucila
Published: February 2023

In the interwar period, Catalan nationalists sought to participate actively in post-World War I political forums in order to inscribe Catalonia in discussions on national minorities. Figures like Lluís Nicolau d’Olwer (1888-1961) or Joan Estelrich (1896-1958) unsuccessfully fought to have their claims heard at organisations such as the League of Nations. This has been considered a form of protodiplomacy (Núñez-Seixas 2010). This paper will explore the ways in which Catalan politicians and intellectuals, such as the abovementioned Lluís Nicolau d’Olwer and Josep Puig i Cadafalch (1867-1956), engaged in forms of protodiplomacy in the same period, in the context of the Byzantine Studies Congresses that were organised in South-Eastern Europe in 1924 and 1927. This engagement is significant for a number of reasons. Firstly, it shows that territorial entities with conflicting agendas (separatist, in the case of Catalonia; agglutinating, in the case of Romania) could build narratives that reciprocally reinforced each other’s nationalist objectives. Secondly, it alters the conventional narrative according to which Josep Puig i Cadafalch, former president of the Catalan Mancomunitat (1917-1923) retired from politics after General Primo de Rivera’s coup d’état, and devoted himself to merely academic practices (e.g. Balcells 2013). Instead, his participation in those Congresses should be framed in the both implicit and explicit political character of those meetings (Maufroy 2010). Finally, the approach of this paper highlights the eminently transnational character of the spaces in which those nationalist narratives and claims where discussed and negotiated (Alcalde 2018).
Peuples et Frontières: a Europeanist Journal against the Europe of the Treaties (1936-1939)
Authors: Carney Sébastien
Published: February 2023

From 1919 some voices were raised in Brittany to claim the right of the Breton people to dispose of themselves. Grouped around the newspaper Breiz Atao, a team of young activists pretends to lead Brittany to autonomy within the framework of a federal Europe, even to independence, which requires a redrawing of borders. Very quickly it was the Europe of the Treaties which was criticized, in a logic of rapprochement with other regional nationalisms, and with Germany, some nationals of which stirred up local claims. This Breton and European activism finds its most complete expression in two reviews: the Bulletin des minorités nationales en France, created in 1936, and quickly renamed Peuples et Frontières (Peoples and Borders). Why and how did a few Breton activists without an audience pretend to get involved in European geopolitics? What interest did their journal defend?
After being disappointed by Panceltism, these Breton nationalists first turned to the oppressed minorities of France, who gathered in 1927 in a committee without a future. The federalism promoted by this committee finds new life in the Bulletin des minorités nationales en France, which soon spread to Europe under the name Peuples et Frontières, in accordance with the wishes of some German activists, including Gerhard von Tevenar. Consequently, the review defends German interests in Central Europe, since asking for the revision of the Treaties would make it possible to defend Breton interests in France. Largely, this monthly was moderated by Yann Fouéré, whose network extended to central Europe, that was considered as a laboratory.
Archival Review: The Welsh Political Archive at the National Library of Wales
Authors: Phillips Rob
Published: February 2023

The Welsh Political Archive (WPA) is a dedicated programme within the NLW (The National Library of Wales), established in 1983, to collect, catalogue and promote archival material which reflects the political life of Wales.
State of Nationalism (SoN): Nationalism and Social Class
Authors: Kostantaras Dean
Published: February 2023

The State of Nationalism (SoN) seeks to create a comprehensive guide to nationalism. This installment of SoN is dedicated to a review and annotated bibliography about 'Social Class'.
Trajectories and functions of Catalan nationalism since the 19th century
Authors: Puhle Hans-Jürgen
Published: February 2023

This article attempts to outline, in a brief summary, the outstanding features of the longue dur trajectories of the movements, concepts, alliances and politics of Catalan nationalism and their functions for Catalan and Spanish politics through the last century-and-a-half. It tries to characterise the basic lines of the social background, the interests, programme and ideology of the Catalan nationalists, and to look into their achievements and limitations, their internal cleavages and divisions, and their (possible or impossible) alliances with Spanish political forces, and with one another. Particular attention is given to processes of change and to the respective thresholds involved, but also to a significant number of continuities through the various stages of Catalanism and Catalan nationalism from its beginning to the present. Among the continuities can be found divided actors (and rivalries), the long dominance of party politics and pacts (pactisme), and the insistence on self-determination. The most important changes are reflected in an overall movement, over time, from regionalism to autonomism to separatism, usually mixed with characteristic elements of federalism, and notwithstanding the existence of overlapping, parallel and hybrid strategies. The article finishes with an outlook to the threats and models for the 21st century.
How liberalism assimilates minorities. The failure to develop a Welsh national movement in the nineteenth century
Authors: Brooks Simon
Published: February 2023

In the nineteenth century, Wales contained all the necessary building blocks for the development of a successful ethnolinguistic nationalism on the European pattern. However, no serious nationalist movement emerged, and that nationalism which did develop was civic rather than linguistic in nature. This course of events is explained by the unusual nature of the British state, and the development of ideologies within it. Britain was a liberal state, and Wales was the most liberal part of Britain. The emphasis of liberalism on personal advancement and individual emancipation came at the expense of communitarian loyalties. Inevitably, this undermined the idea of nation as an intellectual concept. Welsh radicals argued in sincerity for social justice, but justice could only be achieved on the basis of a common citizenship, which was shared with all in the British Isles and defined by the English language. Because of the liberal emphasis on shared civic space and cultural universalism, the Welsh attachment to radical politics led to cultural assimilation.
The cradle of Catalan separatism. White-collars in Barcelona during WWI
Authors: Esculies Joan
Published: February 2023

This paper attempts to explain why, in Barcelona during World War I, Catalan white-collars a part of them radicalised their Catalan nationalism positions and can be considered the cradle of Catalan separatism. In order to accomplish it, the article provides an overview of the origins and social background of Catalan white-collars and their relationship with bourgeois and blue-collar workers. The analysis presents the major pillars of the separatist white-collars and it depicts the profile of the enemies ofthis ideology: Spanish ultra-nationalism. Although references to previous periods are made, the article focuses on the WWI period (1914-1919) when the process took place.
History, historiography and the ambiguities of Catalan nationalism
Authors: Ucelay-Da Cal Enric
Published: February 2023

In this essay, the author attempts to realise two different and not completely complementary objectives. On the one hand, his intention is to familiarise readers with the dynamics of Catalan history over time, as well as with the ways in which Catalan historians in particular have helped to shape and determine Catalan nationalist discourse. On the other hand, the author has tried to question the obsessively political nature of both national and nationalist historiography, and the numerous contradictions involved, especially when the object of study is as imprecise as any political projection or desire.
Bibliography of recent research on Upper Silesia
Authors: Ther Philipp
Published: February 2023

The following bibliography contains the most recent research on Upper Silesia.
Comparison of methods for detecting anomalous behavior on large-scale computer-based exams based on response time and responses
Authors: Hadiana Deni , Hayat Bahrul , Tola Burhanuddin
Published: February 2023

This study aims to determine the anomalous index (indeks anomali or IA) that considers both response time and responses and compares it with response time effort (RTE) or rapid guessing (tebakan cepat or TC) on various thresholds. Response time and responses from 732 examinees are in natural science subjects consist of 40 multiple choice items with four answer choices. Response time and responses are analyzed to obtain descriptive statistics related to them, calculate the TC and IA index using two methods of the threshold, the first method (M1) is a visualization of identification, and the second method (M2) is based on the amount of time spent responding to each item related to the complexity of items, as proposed by Nitko. The performance of the IA and TC scores is compared related to validity and reliability. The coefficient alpha of IAM1 score 0.84, the coefficient alpha of IAM2 0.82. Both values of the alpha coefficient have fulfilled the reliability requirements of the index determination. The IA proposed in this study has a high correlation with ERP, which is commonly used to determine the solution behavior's magnitude and rapid guessing. The correlation value of IAM1 with TCM1 0.86, the correlation value of IAM2 with TCM2 0.89, and this high correlation value shows that there is a strong relationship between IA and TC. Determination of threshold time uses three categories of multiple choices item that reveal IA and TC distributions that are close to normal distribution so that it reflects natural empirical conditions.
Multiple intelligences instrument development: Identification system of multiple intelligences tutor
Authors: Berlian Mery , Mujtahid Iqbal Miftakhul , Vebrianto Rian , Thahir Musa
Published: February 2023

Research instruments are an important factor in a study in which the truth of researched results lies that determines the conclusion. Instruments are used to collect data and measure a research variable's object. This study aimed to retest a valid, consistent, and reliable instrument related to multiple intelligences previously developed by McClellan Conti. In this study, Multiple intelligences adapted from American psychologist, Howard Gardner, consisted of nine constructs, namely: (1) physical/kinesthetic, (2) existential/spiritual, (3) interpersonal, (4) intrapersonal, (5) logical thinking, (6) musical/rhythmic, (7) naturalistic, (8) verbal, and (9) visual. Designed as a survey study, it involved 140 respondents from primary education tutors of Universitas Terbuka at Pekanbaru selected using simple random sampling techniques. The data was analyzed using SPSS version 23.00 for Windows. The results showed that all questionnaire items were valid and reliable with a high average Cronbach Alpha reliability value (0.763 0.6), and every statement item has a high value (0.786 – 0.887) with a total construct value of 0.859.  This study provides an alternative assessment related to multiple intelligence. Knowing each tutor's multiple intelligences will make the tutor focus more on the superiority of his intelligence. This will have good consequences for the development of the student learning process.
Evaluation of the implementation of professional development efforts in improving the professionalism of Geography teachers
Authors: Yuniandita Alfin Nuramalia , Mukminan Mukminan
Published: February 2023

This study aims to determine how the implementation of teacher professional development efforts and the government and/or related agencies' participation in supporting teacher professional improvement can formulate sustainable professional development efforts in improving the professionalism of high school geography teachers in Brebes Regency. This evaluation study used the discrepancy model. The method used was descriptive quantitative and analyzed using percentage descriptive techniques. The data in this evaluation study were collected through questionnaires, interviews, and observations. The sample in this study consisted of 30 high school Geography teachers in Brebes Regency, while the sampling technique used was disproportionate stratified random sampling. Regardless of the results of the study that Geography teachers had a good understanding of the duties and obligations that had to be fulfilled as professional teachers, that efforts for sustainable professional development had not been fully implemented properly. The result shows that the Sustainable Professional Development efforts carried out by Geography teachers are in the criteria of “Good Enough” with an average score of 66.83 (out of a maximum score of 120). From several programs supporting the teachers’ professional development, only a few programs are routinely carried out by Geography teachers, including internal coaching by supervisors, Geography subject forum activities, and workshops. Besides, several professional development programs deserve special attention from the government due to the lack of teacher participation, namely apprenticeships, short courses, distance learning, level training, and further education, given that some of these programs provide opportunities for teachers to update and develop their knowledge.
Evaluation of education and training programs in Solo Technopark Central Java in Indonesia
Authors: Sudiyatno Sudiyatno , Wulandari Iswahyuni
Published: February 2023

This study aims to evaluate the implementation of a training program for youth in Solo Technopark, Central Java, Indonesia, and get important feedback and recommendations to increase its effectiveness. The evaluation method used is based on four levels of the Kirkpatrick model to assess: (1) participants' reaction to the training program (to the contents, facilitators, and facilities); (2) training participants' learning (knowledge and basic skills); (3) change of participant behaviors; and (4) succeed of the training participants based on competence skills and rate of graduate employability and employer’s satisfaction. Research respondents were 47 training participants from four optional courses at the reaction and learning level. There were 59 alumni, three training instructors, and one employer as the respondents at the behavior and results level. Data were collected using questionnaires, interviews, documentation, and an observation checklist. The data were analyzed using the quantitative descriptive analysis method. The study shows that: (1) at the reaction level, most training participants are satisfied with the training program, instructors, and facilities; (2) at the learning level, most participants have a good category in knowledge and basic skills; (3) at the behavior level, participants can implement the attitudes and major skills at a good level; (4) at the results level, alumni have high skills at workplaces; they have been employed in various industries, and the alumni's employability rate is less than 50%. To increase the low rate of employability in the labor market, Solo Technopark needs to improve alumni networking and collaboration with industries and employers.
Gross domestic product and geographic area as social determinants of child stunting and severe stunting in Indonesia: A multilevel analysis
Authors: Siswati Tri , Waris Lukman , Paramashanti Bunga Astria , Kusnanto Hari , Susilo Joko
Published: February 2023

Background: In Indonesia, socioeconomic disparities in childhood stunting is vast.

Objectives: This study aimed to analyze the social determinants of stunting and severe stunting children in Indonesia.

Methods: We analyzed data from cross-sectional surveys of Indonesia’s National Basic Health Research in 2013, the Central Bureau of Statistics, and the Ministry of Finance. Our samples were 3953 children aged 6-23 months and 10215 children aged 24-59 months. Dependent variables were the prevalence of child stunting and severe stunting. Independent variables covered factors at the social level while controlling structural and biological level-factors. Data were analyzed using multilevel analysis using generalized linear mixed models (GLMM).

Results: Gross domestic product was associated with the reduced risk of stunting among children aged 6-23 months (ARRR= 0.99; 95%CI: 0.98-1.00) and 24-59 months (ARRR= 0.99; 95%CI: 0.97-0.99) as well as with the decreased risk of severe stunting among 6-23 months (ARRR= 0.99; 95%CI: 0.98-1.00) and 24-59 months (ARRR= 0.99; 95%CI: 0.97-0.99) old children. Tax ratio was a significant factor only for the severe stunting among 24-59 months old children (ARRR= 0.98; 95%CI: 0.96-0.99). There was also a geographical difference related to stunting and severe stunting.

Conclusions: Equitable economic growth is an essential factor to improve the health and welfare of stunting and severe stunting children across the geographical setting in Indonesia.

 
The Use of Sensors to Detect Anxiety for In-the-Moment Intervention: Scoping Review
Authors: Dobson Rosie , Li Linwei Lily , Garner Katie , Tane Taria , McCool Judith , Whittaker Robyn
Published: February 2023

Background

With anxiety a growing issue and barriers to accessing support services, there is a need for innovative solutions to provide early intervention. In-the-moment interventions support individuals to recognize early signs of distress and use coping mechanisms to prevent or manage this distress. There is potential for wearable sensors linked to an individual’s mobile phone to provide in-the-moment support tailored to individual needs and physiological responses.

Objective

The aim of this scoping review is to examine the role of sensors in detecting the physiological signs of anxiety to initiate and direct interventions for its management.

Methods

Relevant studies were identified through searches conducted in Embase, MEDLINE, APA PsycINFO, ProQuest, and Scopus. Studies were identified if they were conducted with people with stress or anxiety or at risk of anxiety and included a wearable sensor providing real-time data for in-the-moment management of anxiety.

Results

Of the 1087 studies identified, 11 studies were included in the review, including 5 randomized controlled trials and 6 pilot or pretesting studies. The results showed that most studies successfully demonstrated improvements in their target variables. This included overall anxiety and stress levels, and the implementation of in-the-moment stress and anxiety management techniques such as diaphragmatic breathing. There was wide variation in the types of sensors used, physiological measures, and sensor-linked interventions.

Conclusions

This review indicates that sensors are potentially a useful tool in detecting anxiety and facilitating the implementation of a known control mechanism to reduce anxiety and improve mood, but further work is needed to understand the acceptability and effectiveness of this type of intervention.
Public Perceptions of the Food and Drug Administration’s Proposed Rules Prohibiting Menthol Cigarettes on Twitter: Observational Study
Authors: Zhou Runtao , Tang Qihang , Xie Zidian , Li Dongmei
Published: February 2023

Background

On April 28, 2022, the Food and Drug Administration (FDA) proposed rules that prohibited all menthol-flavored cigarettes and other flavored cigars to prevent the initiation of tobacco use in youth and reduce tobacco-related diseases and death.

Objective

The objective of this study was to investigate public perceptions of the FDA’s proposed menthol cigarette rules on Twitter.

Methods

Through the Twitter streaming application programming interface, tobacco-related tweets were collected between April 28, 2022, and May 27, 2022, using a set of keywords, such as smoking, cigarette, and nicotine. Furthermore, 1941 tweets related to the FDA’s proposed menthol cigarette rules were extracted. Based on 300 randomly selected example tweets, the codebook for the attitudes toward the FDA’s proposed rules and related topics was developed by 2 researchers and was used to label the rest of the tweets.

Results

Among tweets related to the FDA’s proposed menthol cigarette rules, 536 (27.61%) showed a positive attitude, 443 (22.82%) had a negative attitude, and 962 (49.56%) had a neutral attitude toward the proposed rules. Social justice (210/536, 39%) and health issues (117/536, 22%) were two major topics in tweets with a positive attitude. For tweets with a negative attitude, alternative tobacco or nicotine products (127/443, 29%) and racial discrimination (84/536, 16%) were two of the most popular topics.

Conclusions

In general, the public had a positive attitude toward the FDA’s proposed menthol cigarette rules. Our study provides important information to the FDA on the public perceptions of the proposed menthol cigarette rules, which will be helpful for future FDA regulations on menthol cigarettes.
Diagnostic Accuracy and Confidence in Management of Forearm and Hand Fractures Among Foundation Doctors in the Accident and Emergency Department: Survey Study (Preprint)
Authors: Gompels Ben , Rusby Tobin , Limb Richard , Ralte Peter
Published: February 2023

BACKGROUND

Accurate interpretation of radiographs is crucial for junior doctors in the accident and emergency (A&E) department (the emergency medicine department). However, it remains a significant challenge and a leading cause of diagnostic errors.

OBJECTIVE

This study aimed to evaluate the accuracy and confidence of foundation doctors (doctors within their first 2 years of qualifying) in correctly interpreting and managing forearm and hand fractures on plain radiographs.

METHODS

A total of 42 foundation doctors with less than 2 years of experience and no prior emergency medicine training who worked in a large district general hospital participated in a web-based questionnaire. The questionnaire consisted of 3 case studies: distal radius fracture, scaphoid fracture, and a normal radiograph. Respondents were required to identify the presence or absence of a fracture, determine the fracture location, suggest appropriate management, and rate their confidence on a Likert scale.

RESULTS

Overall, 48% (61/126) of respondents accurately identified the presence and location of fractures. The correct management option was chosen by 64% (81/126) of respondents. The median diagnostic confidence score was 4 of 10, with a mean diagnostic certainty of 4.4 of 10. Notably, respondents exhibited a significantly lower confidence score for the normal radiograph compared to the distal radius fracture radiograph (P=.01).

CONCLUSIONS

This study reveals diagnostic uncertainty among foundation doctors in interpreting plain radiographs, with a notable inclination toward overdiagnosing fractures. The findings emphasize the need for close supervision and senior support to mitigate diagnostic errors. Further training and educational interventions are warranted to improve the accuracy and confidence of junior doctors in radiographic interpretation. This study has several limitations, including a small sample size and reliance on self-reported data. The findings may not be generalizable to other health care settings or specialties. Future research should aim for larger, more diverse samples and explore the impact of specific educational interventions on diagnostic accuracy and confidence.
Sistemas de Respuesta Inmediata combinada con ciclos de Generación, Evaluación y Modificación en Química General
Authors: Flores-Morales Patricio
Published: February 2023

Los Sistemas de Respuesta Inmediata (SRI) son aplicaciones o programas que permiten la medición del aprendizaje con retroalimentación inmediata para quienes las usan. Gracias a la pandemia, se convirtieron en instrumentos de evaluación masiva. Sin embargo, su uso no es muy distinto al de las cliqueras o tarjetas en aula. Por lo mismo, una pedagogía que pudiera incorporar esta TIC dentro de la sala de clases como un elemento potenciador del aprendizaje es un desafío actual. La Teoría de la Enseñanza y Aprendizaje de la Ciencia basada en la Revisión y Construcción de Modelos Mentales proporciona un andamiaje para lograr este objetivo al hacer reflexionar al estudiantado partiendo de un SRI.En esta investigación se muestra cómo gracias a la combinación de una parte de la teoría mencionada con los SRI, se logra un aprendizaje profundo en algunos tópicos de Química General. Los resultados muestran que gracias a esta unión el estudiantado participa, cambia sus preconcepciones por ideas de rigurosidad científica superior y obtiene resultados positivos comparando evaluaciones previas y posteriores.
Síntesis y evaluación de fotocatalizadores TiO2/carbón activo: un enfoque multidisciplinar y cooperativo para estudiantes de ingeniería química
Authors: Peñas-Garzón Manuel , Moreno-Medina Irene , Bedia Jorge , Belver Carolina
Published: February 2023

El uso de la fotocatálisis para la eliminación de contaminantes presentes en las masas de agua ha experimentado una gran atención en las últimas décadas, y esto debería reflejarse también en la formación científica de los y las estudiantes del grado de ingeniería química. Con el objetivo de ampliar sus competencias en esta materia, se presenta un experimento multidisciplinar de cinco sesiones en el que se proporciona un espacio para el trabajo cooperativo. Este se compone de tres etapas secuenciales en el laboratorio: i) síntesis de fotocatalizadores, TiO2 sin soportar y soportado sobre carbón activo (CA, incluyendo la descripción paso a paso de la preparación del CA y la síntesis solvotermal del TiO2); ii) caracterización estructural y óptica de las muestras; y iii) evaluación de la actividad fotocatalítica (en la degradación de acetaminofeno, comercialmente paracetamol, utilizando luz solar) y la separación de la disolución; más una adicional de presentación y discusión de resultados. Los resultados del experimento mostraron que el TiO2 no soportado realiza la degradación más rápida del contaminante, mientras que el fotocatalizador soportado (TiO2/CA) presenta la mayor velocidad de sedimentación (y, por tanto, una recuperación más fácil del medio). El objetivo de esta actividad es fomentar en los y las estudiantes la capacidad crítica para considerar los dos aspectos de la aplicación general de un fotocatalizador, dándoles una visión multidisciplinar sobre cómo los fotocatalizadores pueden ser empleados para la protección del medio ambiente, desarrollando su concepción sobre justicia ambiental y su importancia en la ingeniería química.
Phaseolus Vulgaris L., or Common Bean, Has A Wide Variety of Chemicals in its Whole Seed Form
Authors: Pathak Suraj kumar , Malik Prof. Dr. Jitendra
Published: February 2023

Abstract: The Phaseolus vulgaris L. bean, also known as the common bean, is a very valuable crop that is grown and eaten all over the world. P. vulgaris is an important food crop because it has a lot of protein, carbs, and fiber. Some people think that bean starch is harder to break down than grain starch. This is due to the fact that bean starch has a high concentration of amylose, a long amylopectin branch chain, and a backwards tilt. Beans have many different parts, such as peptides, tocopherols, unsaturated fatty acids, and phenolic compounds. Scientists have found that the way beans are made chemically is linked to many important biological processes. Antioxidant, antibacterial, antihyperglycemic, and anticancer properties are some examples of these biological effects. This study gives a summary of the complex chemical makeup of whole common bean seeds and how it relates to the seeds' nutritional and functional qualities.
Introduction to Machine Learning and its Application
Authors: Chaudhari Vipul , Bajpai Adyant , Amrutkar Shruti , Dubey Sukriti , Gupta Dr. Poonam
Published: February 2023

Abstract: This paper describes essential points of machine learning and its application. It seamlessly turns around and teach about the pros and cons of the ML. As well as it covers the real-life application where the machine learning is being used. Different types of machine learning and its algorithms. This paper is giving the detail knowledge about the different algorithms used in machine learning with their applications. There is brief explanation about the Weather Prediction application using the machine learning and also the comparison between various machine learning algorithms used by various researchers for weather prediction.
RANCANG BANGUN PERANGKAT LUNAK PERHITUNGAN METRIK CYCLOMATIC COMPLEXITY BERDASARKAN CONTROL FLOW GRAPH BERBASIS WEB
Authors: Putri Fajarisma Asfiana , Marthasari Gita Indah , Nuryasin Ilyas
Published: February 2023

Pengujian perangkat lunak merupakan salah satu fase yang penting untuk dilakukan dalam membangun perangkat lunak. Salah satu jenis pengujian yang digunakan adalah whitebox testing dengan metode cyclomatic complexity (CC). Salah satu cara yang dapat digunakan untuk pengujian metode cyclomatic complexity adalah dengan menghitung banyaknya node dan edge dari control flow graph (CFG) yang merepresentasikan suatu kode program. Tujuan penelitian ini adalah membuat sebuah perangkat lunak perhitungan otomatis nilai CC dari CFG kode sumber perangkat lunak. Sistem yang dibuat ini akan mendeteksi serta menghitung banyaknya node dan edge dari sebuah gambar CFG yang kemudian diproses untuk mencari nilai cyclomatic complexity berdasarkan metrik CC. Sistem yang dibuat kemudian diuji menggunakan kode sumber website infotech.umm.ac.id. Hasil pengujian yang didapatkan dari implementasi sistem terhadap website infotech adalah nilai cyclomatic complexity sebesar 1,4881 dengan tingkat kompleksitas sistem rendah, nilai resiko rendah, dan bad fix probability sebesar 5%.
Review of Continuing Medical Education in Tick-Borne Disease for Front-Line Providers
Authors: Malkowski Aaron C. , Smith Robert P. , MacQueen Douglas , Mader Emily M.
Published: February 2023

Introduction: Considering increasing rates of tick-borne diseases (TBDs) in the United States, we investigated the scope of continuing medical education (CME) available to physicians on these infections.
Methods: We surveyed online medical board and society databases serving front-line primary and emergency/urgent care providers for the availability of TBD-specific CME between March 2022 and June 2022. We recorded and analyzed opportunity title, author, web address, publication year, learning objectives, CME credit values, and CME credit type.
Results: We identified 70 opportunities across seven databases. Thirty-seven opportunities focused on Lyme disease; 17 covered nine non-Lyme TBDs, and 16 covered general topics on TBDs. Most activities were hosted through family medicine and internal medicine specialty databases.
Conclusion: These findings suggest limited availability of continuing education for multiple life-threatening TBDs of increasing importance in the United States. Increasing the availability of CME materials covering the broad scope of TBDs in targeted specialty areas is essential for increased content exposure and a necessary step to ensure our clinical workforce is adequately prepared to address this growing public health threat.
Does corporate governance influence firm integrated performance?
Authors: Nagendrakumar Nagalingam , Kumarapperuma Chathurini , Malinga Chathura , Gayanthika Kalpani , Amanda Nethmi , Perera Ashini
Published: February 2023

The correlation of corporate governance (CG) with accounting and financial performance (AFP) is highly studied (Ismaeel & Soliman, 2022). However, the correlation of CG with marketing performance (MP) and logistic and supply chain performance (LSCP) is rare. Further, the correlation of CG with firm integrated performance (i.e., AFP, MP, and LSCP) is hard to see. Therefore, the present study explores the association and impact of CG with firm integrated performance (FIP). The study followed the deductive approach and adopted correlation and regression analysis techniques using the secondary data from 132 randomly selected cluster samples from 303 listed companies from the Colombo Stock Exchange (CSE). The study found that CG has a positive but weak relationship and a significant positive impact on the FIP. Thus, this study sheds light on the practical implication that managers must not solely depend on financial performance (FP) but concentrate on FIP when they make strategies for organizational performance and development. The study is original since it has proved that the synergy effect of AFP, MP, and LSCP is much higher than standing alone with CG.
Optimization of expression host for Thermomyces Lanuginosus lipase
Authors: Soni Surabhi , Lali Arvind , Odaneth Annamma
Published: February 2023

In today’s bio-based industry, lipase-catalyzed processes hold eminent
commercial worth, yet their use is restricted owing to low yields, high
production cost, inconsistent reproducibility, and poor performance in
native form. Cloning and expression of multiple lipase genes in various
systems have been investigated in order to produce enzymes for the food
and detergent industries more cheaply since the development of
recombinant DNA technology. The identification of novel lipases is still
hampered by the rather difficult expression of these enzymes. The
expression of lipases still requires a case-to case optimization.
However, the unbiased choice of the appropriate promoter system and host
for a specific protein of interest remains difficult. Here, we concisely
expressed TLIP (Lipase from Thermomyces lanuginosus; mainly used
in the detergent industry) in the frequently used conventional and
alternative host systems, with their unique features, along with
different promoters (T5, T7, aprE and hp4d) to produce recombinant
products. Screening of expression was done among both prokaryotic (
Escherichia coli, Bacillus subtilis) and eukaryotic (
Yarrowia lipolytica) hosts consisting of both intracellular and
secretory expression. E. coli (BL21 Shuffle) and Y.
lipolytica (extracellular) were found to be the best expression systems
for lipase production.
HYRCAN: A Comprehensive Limit Equilibrium Software Package for 2D Slope Stability Analysis
Authors: Mikola Roozbeh Geraili
Published: February 2023

This paper presents the application software HYRCAN, which
evaluates the factor of safety of circular failure surface in soil or
rock slopes. HYRCAN offers a stand-alone windows system that is
very simple to use, yet complex models can be created and analyzed
quickly and easily. The graphical user interface enables quick
generation of advanced models, and the enhanced output facilities
provide a detailed presentation of computational results. The analysis
procedures are fully automated and based on robust numerical procedures.
Embedded scripting languages in HYRCAN enable the user to
interact with and manipulate the models. This paper addresses the
capabilities provided by pre- and post-processors for slope stability
analysis and suggests enhancements and new features likely to be
developed in the near future.
Drug-drug interactions with non-vitamin K oral anticoagulants in the management of cancer-associated thrombosis
Authors: Linden Lorenz Van der , Vanassche Thomas , Cutsem Eric Van , Aelst Lucas Van , Verhamme Peter
Published: February 2023

Abstract Drug-drug interactions (DDIs) are common in cancer management
and complicate the choice of anticoagulation in cancer-associated
thrombosis. Cancer patients incur an increased risk of thrombotic
events. Also, more bleeding events are observed in those who receive
anticoagulation compared to those without cancer. In the treatment of
cancer-associated thrombosis, non-vitamin K oral anticoagulants (NOACs)
are at least as effective as low-molecular weight heparins, which became
the standard of care after several trials demonstrated superiority over
vitamin K antagonists. Non-inferiority has been shown for rivaroxaban,
edoxaban and apixaban with a signal of fewer recurrent thrombotic
events, albeit with an increase in bleeding events. Yet, potentially
major drug-drug interactions have been identified as a reason to
withhold NOACs and to rather choose an alternative. Furthermore,
practical guidance on what constitutes a major interaction and/or how to
deal with these interactions in clinical practice is limited. Hence,
here we have provided a framework to allow clinicians to better deal
with drug-drug interactions between NOACs and cancer therapies in the
management of cancer-associated thrombosis. In this review we have
discussed the current literature, how the pharmacokinetic profile links
to the label information on DDI, and have provided a practical proposal,
applied to a clinical case. Key words: drug-drug interactions,
anticoagulation, non-vitamin K oral anticoagulants, cancer, cancer
associated thrombosis
Genital warts in women - 12-year incidence rate trends in Novi Sad
Authors: Strbac Mirjana , Nikolic Natasa , Bojat Veselin , Smiljanic Nina , Petrovic Vladimir , Ristic Mioljub
Published: February 2023

Introduction. Data on the incidence and age distribution of women with
genital warts in Serbia are limited. The aim of this study was to determine
the epidemiological characteristics of genital warts in the female
population aged 15 - 69 years in Novi Sad. Material and Methods. A
descriptive epidemiological study was conducted using the data of the
Primary Health Care Center ?Novi Sad?. The study data refer to women
examined by primary care gynecologists during a 12-year period (2010 -
2021). Results. During the observed period, 654 out of 240,494 examined
women aged 15 - 69 years, i.e. 609 out of 164,578 women aged 15 - 49 years,
had newly diagnosed genital warts. The cumulative overall incidence rate of
genital warts in women aged 15 - 69 was 2.7/1,000 (95% confidence interval
2.64 - 2.77), while in women aged 15 - 49 it was 3.7/1,000 (95% confidence
interval 3.61 - 3.79). The trend in genital warts incidence in both observed
age groups was stable. The highest annual incidence rate of genital warts
was registered among women aged 15 - 19 years, and it was statistically
significantly (p < 0.0001) higher than in all the other age groups. The
annual estimated number of women with newly diagnosed genital warts in Novi
Sad was 547, of which 187 (34.2%) were women aged 15 - 19 years. Conclusion.
Our results provide essential epidemiological data that may be used as the
basis for future population studies, as well as for the evaluation of the
effectiveness of the human papillomavirus vaccination campaign, after its
wide implementation in the vulnerable population.