bluuebunny/crossref_metadata_2025 huggingface dataset:
Identification of a Novel FUS/ETV4 Fusion and Comparative Analysis with Other Ewing Sarcoma Fusion Proteins
Authors: Boone Megann A. , Taslim Cenny , Crow Jesse C. , Selich-Anderson Julia , Watson Mike , Heppner Peter , Hamill James , Wood Andrew C. , Lessnick Stephen L. , Winstanley Mark
Published: August 2021

Ewing sarcoma is a pediatric bone cancer defined by a chromosomal translocation fusing one of the FET family members to an ETS transcription factor. There have been seven reported chromosomal translocations, with the most recent reported over a decade ago. We now report a novel FET/ETS translocation involving FUS and ETV4 detected in a patient with Ewing sarcoma. Here, we characterized FUS/ETV4 by performing genomic localization and transcriptional regulatory studies on numerous FET/ETS fusions in a Ewing sarcoma cellular model. Through this comparative analysis, we demonstrate significant similarities across these fusions, and in doing so, validate FUS/ETV4 as a bona fide Ewing sarcoma translocation. This study presents the first genomic comparison of Ewing sarcoma–associated translocations and reveals that the FET/ETS fusions share highly similar, but not identical, genomic localization and transcriptional regulation patterns. These data strengthen the notion that FET/ETS fusions are key drivers of, and thus pathognomonic for, Ewing sarcoma.

Implications:

Identification and initial characterization of the novel Ewing sarcoma fusion, FUS/ETV4, expands the family of Ewing fusions and extends the diagnostic possibilities for this aggressive tumor of adolescents and young adults.
Calyceal Diverticula Disease: Diagnosis and Management Options in the Era of Non-Contrast CT Scan
Authors: Abushamma Faris , Ito Hiroki , Aboumarzouk Omar , Timoney Anthony , Collin Neil , Keeley Francis X.
Published: August 2021

Introduction: Calyceal diverticula (CD) are traditionally diagnosed by contrast studies. However, non-contrast CT is the standard imaging modality for kidney stones. Therefore, we aimed to determine if the lack of contrast imaging affected outcomes of the management of symptomatic CD with stone. Materials and Methods: This is a retrospective study of patients diagnosed with CD with intracalyceal stone from 2000 to 2017 analyzing demographics, clinical data, and success of different treatment options. The timing of CD diagnosis is correlated to the success of the first treatment. Results: Forty-eight patients were found. CD was diagnosed prior to intervention in 20 (42%) cases and intraoperatively during flexible ureteroscopy in 17 (35%) and 11 (23%) cases were diagnosed after failed intervention, mainly ESWL. We found that the success rate of treatment was highly affected by the timing and modality of diagnosis. Preoperative diagnosis of CD was associated with 69% success rate of the first intervention. In contrast, there was a 0% success rate of first treatment if CD was not diagnosed with contrast imaging. Furthermore, univariate analysis showed no significant association between sociodemographics and clinical variables and success treatment (p > 0.05). Conclusions: The delay in diagnosing CD with stone contributes significantly to the success rate and the number of treatments.
Baseline Values of Nonalcoholic Fatty Liver Disease Scores and Its Risk Assessment in Patients with Type 2 Diabetes Mellitus
Authors: Joshi Kalpesh , Chandrakar Santwana , Patil Smita
Published: August 2021

Introduction: The prevalence of nonalcoholic fatty liver disease (NAFLD) is increasing and is fueled by a twin-epidemic of obesity and diabetes mellitus in India. The objective of the study was to estimate various noninvasive NAFLD scores (NINS) for the baseline risk-assessment of NAFLD in patients with type 2 diabetes mellitus (T2DM). Methods: An observational, cross-sectional, open label, study of investigator-rated NINS was conducted ensuring adherence to relevant ethical standards. Results: In a 3-month period, 29 patients with T2DM were enrolled (age [mean ± SD]: 55.8 ± 9.72 years; men [n, %]: 18, 62%). One patient (3.45%) by fibrosis-4 index (cutoff for advanced fibrosis ≥2.67) and by AST to platelet ratio index (cutoff ≥0.98); 2 (6.90%) by NAFLD fibrosis score (cutoff ≥0.676); 20 (69%) by body mass index (BMI), AST to ALT ratio, and DM score (BARD; cuff-off ≥2); and 27 (93.10%) by BMI, age, ALT, triglyceride score (cutoff ≥1) indicated high risk for advanced hepatic fibrosis. Only the BARD score (median [min-max]: 3 [1–4]) was elevated above the cutoff values while other scores were below cutoff values. The study failed to demonstrate any correlation between age, gender, anthropometric and metabolic parameters, and NINS. Conclusion: While this study did not demonstrate significant elevation of NINS, scores were found be elevated in some T2DM patients and they may be at high risk of advanced liver fibrosis. Further well-designed studies in this domain are required for early detection, management, and reducing the burden of liver disease in Indian patients with diabetes.
O fim da velha divisão? Público e privado na era da internet
Authors: Miguel Luis Felipe , Meireles Adriana Veloso
Published: August 2021

A emergência da internet impôs desafios à distinção público/privado – que é estruturadora de muitos modelos que pensam o mundo social, de instituições e de normas jurídicas. (1) A homologia entre localização espacial e acesso a uma ou outra esfera é cada vez menos sustentável. (2) Há uma transição sem solução de continuidade da comunicação privada para a exposição pública. (3) A exposição pública perde seu contexto, já que pode ser reprodutível para qualquer outra audiência. (4) A privacidade fica em suspenso diante da vigilância sobre as trocas comunicativas on-line, incluindo aquelas que seriam privativas. O artigo analisa os efeitos da disparidade entre os pressupostos da normatização jurídica vigente e a experiência socialmente estruturada.
O método (auto)biográfico: a perspectiva de um pioneiro: entrevista com Jean Peneff
Authors: Brochier Christophe , Costa Luciano Rodrigues
Published: August 2021

Jean Peneff, nascido em 1939, foi sucessivamente professor de sociologia em Argel, Nantes e Aix-en-Provence. É conhecido por ter sido um teórico e praticante do método biográfico, mas também da observação participante, método que ajudou a popularizar nos anos 1990 entre os sociólogos franceses. Seus livros mais conhecidos se referem à medicina, de que ele foi um dos especialistas mais frequentemente citados na França. Nesta entrevista, realizada nos dias 20 e 30 de novembro de 2020, ele faz um retrospecto de toda a sua trajetória e insiste nas relações entre a vida pessoal e o trabalho sociológico.
Platform workers in Latin America: transnational logics and regional resistances?
Authors: Miguez Pablo , Menendez Nicolas Diana
Published: August 2021

The platforms boom in Latin America is at the current core of the industrial and retail sectors. Platform workers (i.e., drivers, motorcyclists and bikers) started organizing along different repertoires taken from other countries thanks to the global character of productive processes and the weight of migrant labor in services, such as mail, post services, and mobility of people. From a qualitative approach, this article proposes an overview of main organizing experiences and burgeoning struggles in this new context aggravated by the intensification of such platforms within the Covid-19 crisis.
Conditionality and trade union action in the promotion and defence of workers’ rights: the Spanish case
Authors: Guerrero Fernando Elorza , Muñoz Manuel García
Published: August 2021

Conditionality, among other aspects, determines that the regulatory development of the countries that make up the European Union can be carried out, as is usual in the social sphere, without the intervention, or at least minimally, of the workers’ representatives and entrepreneurs, and also from other political formations in the legislative field. Logically, this absence of social or political participation can promote response actions against them, either traditional (strikes, demonstrations, withdrawal of parliamentary support in adoption of legislative measures etc.), or new types (spontaneous concentrations in public places, general assemblies of citizens without a defined convener, appearance of social and political formations of less visible typology, or other similar ones). The financial crisis unleashed at the end of 2007 and the one derived from the health emergency situation due to the global spread of Covid-19, at the beginning of 2020, have precisely encouraged the use of conditionality in the European Union space. However, the way in which conditionality has been developed in one and another crisis in the Spanish State can be said that it has not been identical. Neither have been the reactions of social and political subjects, because if in the first crisis these subjects have experienced a reduction in their functions of participation or intervention in legislative action and in the proposal of political actions, in the second the possibilities of action have been much more significant, and also their contribution to efforts to overcome the crisis situation.
Warring Brothers: Constructing Komatsu’s and Caterpillar’s Globalization
Authors: Goods Caleb , Herod Andrew , Ellem Bradon , Rainnie Al
Published: August 2021

We detail how the world’s two largest engineering machinery firms, Japan’s Komatsu and the us’s Caterpillar, actively managed geographical concerns to become global actors. We argue that their globalization was not a teleological given but had to be proactively made. Both the state and organized labor played significant roles in shaping their geographical evolutions, as did their efforts to outmaneuver each other spatially. Their globalization, then, was part of a broader spatial politics under capitalism.
engano do povo inglês ao fetichismo da representação: Luiz Roberto Salinas Fortes, escritor político
Authors: Vargas Thiago
Published: August 2021

Este artigo visa perpassar a trajetória de Luiz Roberto Salinas Fortes, realizando um recorte sob a seguinte perspectiva: retomando seus estudos sobre Rousseau, examinaremos como sua formação filosófica serviu como ferramenta para que, nos últimos anos de sua vida, pudesseconstituir uma escrita crítica e de intervenção, cuja questão central gira em torna da noção de democracia. Neste sentido, na década de 1980 é organizada uma coletânea intitulada “A Constituinte em Debate”, obra na qual escreve um texto fundamental para pensarmos e compreendermos os impasses que circundavam o período de formação da Constituinte. Neste artigo, Salinas Fortes se preocupa com questões que poderiam afastar o processo de suas finalidades democratizantes. Em poucas palavras, a questão era como realizar uma democracia efetiva noBrasil, tendo em vista os arrepios que o conceito de “democracia direta” causava entre aqueles que Salinas Fortes apelida de “liberais”. Prescindindo de um debate público mais extenso e de um envolvimento mais direto da população na formação das normas constitucionais, termos como “soberania”, “igualdade”, “poder do povo”, e, sobretudo, as questões relacionadas aos usos do conceito de “democracia representativa”, corriam, então, o risco de serem corriqueiramenteutilizados ideologicamente, de forma a encobrir os reais problemas que se colocavam nesta fase de transição. Segundo Salinas Fortes, falhar em relação a este debate público seria adentrarmos em um “arremedo de democracia”: eis, então, que entra em cena o papel crucial do escritor político e do intelectual público. É neste contexto que surge uma privilegiada questão, ainda hoje a ser respondida: como realizar, no Brasil, um projeto de cidadania plena?
Entre paredes estudantis e institucionais: o movimento estudantil, suas posições e lutas
Authors: Pimentel Orlando Lima
Published: August 2021

Pretendemos desenvolver neste texto comentários sobre o movimento estudantil do curso de filosofia da Universidade de São Paulo (USP), baseando-nos nas experiências de luta de 2016 e problematizando as contradições envoltas na pauta por permanência estudantil, feitas ao longo do mesmo ano. Para tanto, convidaremos o leitor a adotar uma posição quanto ao problema da interrupção da vida acadêmica normal dos estudantes, em situações adversas (piquetes ou reformasimprevistas na estrutura física do patrimônio universitário). Por fim, partindo dos possíveis posicionamentos quanto ao cenário proposto, poderemos avaliar as predisposições políticas estudantis para lutar, seguindo ou não as regras e protocolos das estruturas oficiais de poder,internas à universidade.
Ambivalência da política no prólogo d’a cidade de deus, de Agostinho
Authors: Silva Filho Luiz Marcos da
Published: August 2021

No prólogo d’A cidade de Deus, Agostinho apresenta ambivalente concepção de política, pois a política adquire ou positividade ou negatividade conforme a identidade ou a contradição de uma civitas ou res publica consigo mesma. Mais precisamente, a cidade celeste, que guarda dois modos de existência, um na história, outro na eternidade, conquista progressivamente identidade na medida em que na história há processo coerente dela em direção a seu modo de existência por excelência, na eternidade; já a cidade terrena existe na história em contradição e conflito, ao tornar-se escrava da própria libido de dominação, de maneira que sua história é de progressiva danação e perda de ser. Uma cidade guarda, pois, estatuto político a despeito de sua orientação ou de sua desorientação moral. Além do mais, nos limites do prólogo, Agostinho explicita que o fundamento da política não é nem a natureza, nem a razão.
Espetáculo desprovido de arte: o tema do luxo em Rousseau
Authors: Nascimento Luís Fernandes dos Santos
Published: August 2021

O presente artigo analisa a atitude peculiar que Rousseau assume na célebre "querela do luxo": diante da valorização do gosto refinado nas artes em um século marcado pelo espírito de galanteria e pelo modelo de vida fútil e pomposa da corte, é na condição de escritor que Rousseau, paradoxal e conscientemente, denuncia os efeitos sociais nocivos do luxo sobre os costumes.
Por uma semiótica social das identidades geoculturais: fundamentos teóricos e um primeiro quadrado semiótico
Authors: Montoro Juan Manuel , Moreno Barreneche Sebastián
Published: August 2021

Como parte dos nossos esforços por desenvolver uma semiótica social para o estudo das identidades geoculturais – as identidades coletivas ancoradas em uma materialidade geográfica específica, ou fato –, este artigo apresenta as bases teóricas para essa perspectiva e, mediante o uso do quadrado semiótico, propõe uma tipologia inicial em relação aos objetos de estudo dos quais um enfoque assim poderia se ocupar. Após a argumentação sobre aquilo no que um enfoque semiótico das identidades coletivas poderia consistir, o artigo se dirige ao caso específico das identidades geoculturais como um subtipo distinto dessas, e propõe uma tipologia baseada no quadrado semiótico. Essa tipologia, construída sobre a base das categorias de continuidade e descontinuidade, é composta de quatro posições: identidades nacionais, transnacionais, subnacionais e supranacionais.
Entre o peixe e o xamã: processos semióticos no encontro intercultural
Authors: Bueno Alexandre Marcelo
Published: August 2021

O encontro entre culturas produzido pela imigração pode gerar diferentes tipos de reação da sociedade receptora. Dentre as possibilidades existentes, este trabalho examina dois processos desenvolvidos em diferentes momentos. O primeiro, mais recente, se refere a uma indeterminação de sentidos ligados a traduções de uma figura religiosa pertinente na cultura aimará. O segundo se liga a um processo de normalização da presença de um prato tipicamente original e incomum no Ocidente: o sashimi. Identificar o que elementos tão diferentes têm em comum é um dos objetivos deste trabalho, que discutirá os estranhamentos e as familiaridades de sentidos que o encontro entre duas culturas pode produzir. Para isso, recorremos à semiótica discursiva, em seus desdobramentos mais atuais, assim como à semiótica da cultura e a sua noção de semiosfera. Por fim, tomamos este trabalho como uma proposta inicial para começar a compreender como a interculturalidade é um espaço profícuo para se observar os encaixes e os acolhimentos de significações por culturas muitas vezes distintas e distantes.
A utilização do conceito de cultura em semiótica
Authors: Fiorin José Luiz
Published: August 2021

Este texto tem o objetivo de mostrar o lugar que tem a cultura na arquitetura semiótica. Começa por examinar os textos clássicos que trataram dessa noção e considera insuficientes os conceitos com que operam. Partindo do princípio de que a cultura é uma semiótica-objeto, busca na antropologia um conceito de cultura com que se possa constituí-la. Em seguida, examina as relações entre língua e cultura, observando que aquela é parte desta, mas, ao mesmo tempo, que ela dá à cultura categorias e um princípio de estruturalidade e, por isso, tem nela um papel central.
Semiótica e cultura: campos do conhecimento
Authors: Discini Norma
Published: August 2021

Neste ensaio examinaremos campos do conhecimento, concebidos como articulações semióticas da cultura. Partindo de pressupostos relativos à definição de campo apresentada por Bakhtin (2003), atentaremos para as articulações semióticas internas ao próprio campo – do que despontará o cotejo entre a literatura e a historiografia. Reinterpretado, o conceito de campo remeterá a condições de produção de uma semiose alargada para além dos limites de cada texto, sem que o texto seja descartado como unidade de análise. As condições de produção textual serão observadas conforme a vinculação delas a determinada práxis enunciativa (Bertrand, 1993), e conforme o entendimento de que a cada campo corresponde um modo estável de mobilizar a estesia da linguagem. Tal estabilidade favorecerá a depreensão do éthos da literatura e do éthos da historiografia, concebidos cada qual como determinada hexis corporal (Fontanille, 2008).
Gesto teórico, gesto político. A semiótica diante dos Cultural Studies
Authors: Estay Stange Verónica
Published: August 2021

Princípio de pertinência, eixo da imanência e distância objetivante são regras da semiótica plenamente integradas à metodologia do investigador. São regras que se apresentam como evidentes frente a objetos relativamente “neutros”, do ponto de vista ético e político. No conjunto dos fenômenos culturais que a semiótica pode considerar como corpus, entretanto, alguns desses fenômenos interpelam-nos diretamente, e de modo tão radical que nosso primeiro impulso seria produzir um discurso militante, desviando-nos (realmente nos desviando?) das possibilidades que essa disciplina nos oferece. Assassinatos em massa, crimes contra a humanidade: como podemos nos referir a tais “objetos”, axiologicamente tão marcados, sem romper com as regras de análise e, ao mesmo tempo, sem produzir um discurso árido, insensível, desumanizado? Nesses casos, até que ponto é possível recorrer ao “gesto teórico” próprio da semiótica?Os Cultural Studies têm enfrentado o problema de frente. Motivado por um “gesto político”, o investigador constrói sua legitimidade com base em sua implicação direta nas problemáticas com que trabalha. Nesse quadro, o semioticista não pode deixar de questionar as bases de seu posicionamento, perguntando-se com que ele pode colaborar, dentro dos limites de sua disciplina, respeitando (ou não) os princípios que a definem. Esse é o objetivo desta contribuição, que coteja a perspectiva semiótica e o enfoque dos Cultural Studies, retomando reflexões desenvolvidas previamente em colaboração com Raphaël Horrein. A partir dessas reflexões, proponho-me a abordar os desafios que se colocam para nossa disciplina, bem como suas possíveis contribuições frente a fenômenos culturais “extremos”, vinculados à violência política.
Análises de mobilidade no litoral sul de Santa Catarina entre 2000-500 cal AP
Authors: Merencio Fabiana Terhaag , DeBlasis Paulo
Published: August 2021

Os sambaquis possuem uma ocupação longa e antiga no litoral sul de Santa Catarina (7500 a 1500 anos cal AP). A fase final dessa ocupação (a partir de 2000 anos cal AP) é marcada pela diminuição do número de sambaquis construídos e pelas alterações na estratigrafia, com o aumento de sedimento rico em matéria orgânica nas camadas superficiais de sambaquis mais antigos e em sítios discretos na paisagem (sambaquis tardios), que apresentam elementos de continuidade e mudança em relação à ocupação sambaquieira. Esse período é associado às transformações na paisagem costeira durante o Holoceno tardio e, também, aos processos culturais, como o gradual contato entre sambaquieiros e grupos Jê meridionais. A intensificação desse contato é registrada na presença de sítios monticulares e conchíferos com cerâmica Itararé-Taquara (1300-500 anos cal AP). Este artigo apresentará os dados de dispersão espacial e temporal de sítios ativos entre 2000-500 anos cal AP na região de Jaguaruna, através de análises de mobilidade multicritério (caminhos de menor custo) entre sambaquis tardios e sítios com cerâmica Itararé-Taquara. O objetivo é investigar a organização do território e as possíveis relações entre diferentes ocupações nesse período.
Entre estruturas e lembranças: análise da Fábrica de Cerâmica Castanheiro a partir da arqueologia industrial (São Raimundo Nonato/PI)
Authors: Amaral Alencar de Miranda , Ribeiro Alan Alves , Cardoso Rosemary Aparecida
Published: August 2021

Esta pesquisa tem como objeto de estudo a Fábrica de Cerâmica Castanheiro, que manteve suas atividades produtivas entre 1980 e 2003 no bairro Santa Luzia em São Raimundo Nonato/PI. Conjugando os preceitos teórico-metodológicos da arqueologia industrial e urbana às narrativas de moradores locais, buscamos identificar os espaços produtivos da fábrica e problematizar sua importância para a organização espacial do bairro, avaliando como ela influenciou a urbanização, o processo de industrialização e o desenvolvimento econômico do município. Assim, por meio de prospecções, entrevistas semiestruturadas e levantamento documental, identificou-se que a fábrica era composta por cinco estruturas, com funcionalidades distintas: pátio de estocagem; galpão de produção (que abrigava os maquinários); local de armazenamento de matéria-prima (caixão alimentador); galpão de secagem; e espaço associado ao processo de queima (fornos, chaminé, sistema subterrâneo de exaustão). Essas constatações permitiram elaborar um modelo 3D do local. Percebeu-se que a fábrica contribuiu para o crescimento urbano do bairro, fornecendo material para a construção de casas e para seu desenvolvimento socioeconômico, gerando empregos que atraiam pessoas para residirem no bairro e trabalharem na fábrica, e, consequentemente, uma expansão geográfica e demográfica. A fábrica empregou cem funcionários, o que demonstra que a economia municipal contava com uma produção industrial relevante e não se limitava aos setores de serviço e agropastoril.
Redescription of Neponymphes godoii Zamboni, 2001 from the Lower Cretaceous of Brazil, based on the adult and nymphal stages (Hemiptera: Nepomorpha: Belostomatidae)
Authors: MOURA-JÚNIOR DIONIZIO A. , QUINTAS VICTOR , SCHEFFLER SANDRO M. , NEL ANDRÉ , RIBEIRO JOSÉ RICARDO I. , MEJDALANI GABRIEL
Published: August 2021

Neponymphes godoii Zamboni, 2001 is redescribed and illustrated based on specimens from the Lower Cretaceous of Northeastern Brazil (Araripe Basin, Crato Formation; upper Aptian, ~114 Ma). The redescription, based both on the adult and nymphal stages, shows that the external morphological characters of N. godoii were fairly similar to those of recent members of the Belostomatini. Hence, the external morphology in this tribe has apparently not changed much since the Cretaceous.
New species of Chaetonerius Hendel (Diptera: Neriidae) from the Oriental Region
Authors: SEPÚLVEDA TATIANA A. , MARINONI LUCIANE
Published: August 2021

The genus Chaetonerius Hendel has 25 valid species, predominantly distributed in the Afrotropical Region with only three species recorded for the Oriental Region. Herein, we describe a new species, Chaetonerius colavitei sp. n., from material collected in Thailand and Malaysia.
Reconsideration of the species assigned to Faustula Poche, 1926 (Digenea: Microphalloidea) with the proposal of five new genera in the Faustulidae Poche, 1926
Authors: DRONEN NORMAN O. , BLEND CHARLES K. , MOHAMMED ESSA T. , BANNAI MAJID
Published: August 2021

The assignment of species to Faustula Poche, 1926 (Faustulidae Poche, 1926) is reconsidered with the proposal of Gangafaustula n. gen. to accommodate Gangafaustula makundai (Agarwal & Verma, 1981) n. comb.; Gobifaustula n. gen. to accommodate Gobifaustula qikouensis (Qui & Li, 1995) n. comb.; Lingulitrema n. gen. to accommodate Lingulitrema hilsai (Kumar & Agarwal, 1984) n. comb.; Schellitrema n. gen. to accommodate Schellitrema gasterostei (Schell, 1973) n. comb. and Varanasifaustula n. gen. to accommodate Varanasifaustula indica (Agarwal & Verma, 1981) n. comb. Faustula hilsai Kumar & Agarwal, 1984 is determined to be a species distinct from Faustula hilsai Rizvi, 1971 and F. hilsai Rizvi, 1971 is synonymized with Faustula basiri Hafeezullah & Siddiqi, 1970. Faustula rahemii Al-Daraji, 2004 also is synonymized with F. basiri. Faustula pyriformis Kumar & Agarwal, 1984 is transferred to Pronoprymna Poche, 1926 as Pronoprymna pyriformis (Kumar & Agarwal, 1984) n. comb. Faustula sayori (Yamaguti, 1942) Yamaguti, 1958, now synonymized with Pronoprymna petrowi (Layman, 1930) Bray & Gibson, 1980, is renamed Pronoprymna sayori (Yamaguti, 1942) n. comb. based on the presence of an entire (smooth) ovary in P. petrowi (Syn. Monorcheides petrowi Layman, 1930) as originally described, and Faustula varanasiensis (Agarwal & Kumar, 1977) is transferred to Bacciger Nicoll, 1914 as Bacciger varanasiensis (Agarwal & Kumar, 1977) n. comb. We currently propose the following 5 species be retained in Faustula: F. basiri; Faustula brevichrus (Srivastava, 1935) Yamaguti, 1958; Faustula clupeae (Srivastava, 1935) Yamaguti, 1958; Faustula gangetica (Srivastava, 1935) Yamaguti, 1958 and Faustula keksooni (MacCallum, 1918) Poche, 1926. A revised key to the species of Faustula and a key to the genera within the Faustulidae are provided.
Description of the female of Ctenodontina mochica Lamas, revalidation of Ctenodontina carrerai (Hull) stat. rev., and comments on the taxonomy and distribution of Peruvian species of Ctenodontina Enderlein (Diptera: Asilidae: Asilinae)
Authors: SÁNCHEZ PÁVEL , CAMARGO ALEXSSANDRO
Published: August 2021

This work analyzes the status of Peruvian species of Ctenodontina Enderlein, provides the description of the hitherto unknown female of Ctenodontina mochica Lamas, and proposes the revalidation of Ctenodontina carrerai (Hull) stat. rev. (currently regarded as a junior synonym of Ctenodontina maya Carrera & d’Andretta). Additionally, some comments about taxonomy, diagnostic features of male terminalia and distribution of four Peruvian Ctenodontina species, including a modification to the existing key to known species and a map updating their distribution records are given. We report Pachitea Melichar (Hemiptera: Cicadellidae) as prey of Ctenodontina nairae Vieira.
Measurement of Intima-Media Thickness Depending on Intima Media Complex Segmentation by Deep Neural Networks
Authors: Subramaniam Sudha , Jayanthi K. B. , Rajasekaran C. , Sunder C.
Published: August 2021

Intima Media Thickness (IMT) of the carotid artery is an important marker indicating the sign of cardiovascular disease. Automated measurement of IMT requires segmentation of intima media complex (IMC).Traditional methods which use shape, color and texture for classification have poor
generalization capability. This paper proposes two models- the pipeline model and the end-to-end model using Convolutional Neural Networks (CNN) and auto encoder–decoder network respectively. CNN architecture is implemented and tested by varying the number of convolutional layer, size
of the kernel as well as the number of kernels. Auto encoder–decoder performs pixel wise classification using two interconnected pathways for identifying the boundary of lumen-intima (LI) and media adventitia (MA). This helps in reconstruction of the segmented portion for measurement
of IMT. Both methods are tested using a dataset of 550 subjects. The results clearly indicate that end-to-end model has an edge over the pipeline model exhibiting lesser deviation between the automated measurement and the measurement made by the radiologist. The pipeline model however has
better segmentation accuracy when the size of the image used for training is small. The convolutional neural network with auto encoder–decoder proves robust through sparse representation, and faster learning with better generalization. Also, the experimental setup is analyzed by interconnecting
Tensor flow simulated result with Raspberry PI and the outcomes are analyzed.
Classification of Tumor of MRI Brain Image Using Hybrid Feature Extraction Method and Support Vector Machine Classifier
Authors: Kavinkumar K. , Meeradevi T.
Published: August 2021

Brain tumors Analysis is problematic somewhat due to varied size, shape, location of tumor and the appearance and presence of brain tumor. Clinicians and radiologist have difficulty in identifying the tumor type. An efficient hybrid feature extraction method to classify the type of
tumor accurately as meningioma, gliomas and pituitary tumor using SVM (support vector machine) classifier is proposed. The modified Non-Local Means (NLM) filter may be effectively used to get the pure image. The NLM filter is compared with common filters like median and wiener. From the denoised
image the classification is done by training SVM using the texture features from the hybrid and efficient feature extraction technique.The accuracy of the classification is calculated and the SVM classifier training individual type of texture features and also with combined texture features
and the performance is analyzed.
Design and Development of 3D Brain MRI System Using Deep Neural Networks
Authors: Vadivel M. , Ganesan R.
Published: August 2021

A Brain tumor is otherwise known as intracranial tumor. It is a formation of abnormal cells within the brain. A tumor cells grows continuously in the brain and destroys the cells in that specific region causing brain damage. The main problem in the tumor detection is that some normal
brain cells tend to behave as tumor cell which leads to misclassification or unwanted brain surgery. A great challenge for the researchers is to identify the region and appropriate tumor mass. Due to this main reason, automated classifications are acquired for the early detection of brain
tumor. In this research work, two standard datasets were used to test the developed classification algorithms. In this study, four different deep learning models were utilized to identify the accurate fit model to classify the brain tumor. From the results, it was observed that googlenet has
achieved maximum mean classification accuracy of 98.2%, sensitivity 98.67% and specificity 96.17%. Our proposed model can be used to classify the brain tumor more accurately and effectively.
An Efficient Steganalysis of Medical Images by Using Deep Learning Based Discrete Scalable Alex Net Convolutionary Neural Networks Classifier
Authors: Hemalatha J. , Geetha S. , Mohan Sekar , Nivetha S.
Published: August 2021

Steganalysis is the technique that tries to beat steganography by detecting and removing secret information. Steganalysis involves the detection of a message embedded in a picture. Deep Learning (DL) advances have offered alternative approaches to many difficult issues, including the
field of image steganalysis using deep-learning architecture based on convolutionary neural networks (CNN). In recent years, many CNN architectures have been established that have enhanced the exact identification of steganographic images. This work presents a novel architecture which involves
a preprocessing stage using histogram equalization and adaptive recursive median filter banks to reduce image noise, a feature extraction stage using shearlet multilinear local embedding methods and then finally the classification can be done by using the discrete scalable Alex NET CNN classifier.
Performance was evaluated on the RGB-BMP Steganalysis Dataset with different experimental setups. To prove the effectiveness of the suggested algorithm it can be compared with the other existing methodologies. This work improves classification accuracies on all other existing algorithms over
test data.
Effect of Compression Force and Target or Target/Filter Combination on Mean Glandular Dose for Japanese Women in Full-Field Digital Mammography System
Authors: Ishii Mie , Nakamura Mai , Ishii Rie , Shida Keiichi , Hatada Toshikazu , Murakami Noriko , Maeda Megumi , Okamoto Rumi , Shinohara Sae , Araki Fujio , Higashida Yoshiharu
Published: August 2021

We constructed a mammography database of 807 Japanese women and 2,772 images obtained using five commercial full-field digital mammography (FFDM) devices at four different facilities. Five types of mammography devices fabricated by four manufacturers were used: one with a Mo target
(AMULET F), one with Mo and Rh targets (Senographe DS), one with Mo and W targets (AMULET), and two with a W target (MAMMOMAT Fusion and Selenia Dimensions). The purpose of this study was to focus on the mean glandular dose (MGD) in the database and analyze the difference in the MGD of Japanese
women radiographed by mammographic devices with different targets or target/filter combinations. Furthermore, we clarify the difference between the displayed and measured MGDs for the three types of mammography devices. The average compression pressure and compression breast thickness of the
Japanese women in the mammography in this study were 90.9±21.7 N and 43.3±12.9 mm, respectively. The breast compression pressure slightly varied depending on the facility or FFDM device, while the compression breast thickness decreased with the increase in the compression pressure
for all FFDM devices. Differences in breast compression thickness existed depending on the mammography devices. The MGDs of the two types of mammography devices using the W target were smallest (1.335±0.358, 1.218±0.464 mGy). The displayed and measured MGDs of the three types
of FFDM devices had a good correlation. However, the difference between the displayed and measured MGDs of the two devices increased with the MGD.
Analysis of the relationship between preoperative serum tumor marker levels and tumor immune scores in patients with colorectal cancer based on nano-electrochemiluminescence
Authors: Pan Sheng , Niu Ben , Tao Yane , Xia Ganlin , Huang Linfei , Xu Jing , Zhu Lei , Cao Hui
Published: August 2021

Surgery can be used to remove tumors from patients with colon cancer, but some patients have recurrence a short time after the tumor is surgically removed, and the disease-free survival (DFS) period is short. Therefore, if these high-risk patients can be identified as early as possible,
appropriate treatment strategies can be formulated to reduce their postoperative recurrence rate. Tumor immune scores have been proven to be effective in predicting the prognosis of patients, but the scoring can only be performed after the tumor has been removed from the patient. There is
still urgency to find indicators that can predict the prognosis of patients before surgery. We used electrochemiluminescence electrodes modified with nanomaterials to detect the expression of serum markers. After comparison, it was found that the contents of CEA, AFP, CA19-9, and CA125 in
patients with CRC were substantially higher than those with benign colonic disease. Pearson correlation analysis showed that CEA, AFP, CA19-9, and CA125 contents are positive correlated to the patient’s tumor immune score. Further investigation found that patients with high expression
of CEA, AFP, CA19-9, and CA125 had a three-year DFS rate, which was substantially lower than those with low expression. Therefore, our findings suggest that the use of the composite nano-modified electrode electrochemiluminescence method to detect the content of CEA, AFP, CA19-9, and CA125
in patients with colorectal cancer can predict DFS after surgery to a certain extent. Additionally, the perioperative data plan can be adjusted in time according to the expression of tumor markers before surgery.
Process effect analysis on nitride trap distribution in silicon-oxide-nitride-oxide-silicon flash memory based on charge retention model
Authors: Song Yumin , Jeong Jun-Kyo , Yang Seung-Dong , Park Deok-Min , Kang Yun-mi , Lee Ga-Won
Published: August 2021

This paper analyzes data retention characteristics to determine process effects on the trap energy distribution of silicon nitride in silicon-oxide-nitride-oxide-silicon (SONOS) flash memory devices. Nitride films were prepared by low-pressure chemical vapor deposition (LPCVD) and plasma-enhanced
chemical vapor deposition (PECVD). PEVCD films embedded with silicon nanocrystals (Si-NCs) were also compared. The flat band voltage shift in the programmed device was measured at high temperatures to observe the thermal excitation of electrons from the nitride traps in retention mode. The
trap energy distribution was extracted using the charge decay rates, and the experimental results showed that nitride fabricated by PECVD has a shallower trap than nitride fabricated by LPCVD. In nitride with Si-NCs, increased trap sites were observed in the range of 1.14 eV to 1.24 eV.
Effects of different concentrations of artificial joint prosthesis nanoparticles on cytotoxicity and osteogenic differentiation of bone marrow stromal cell (BMSCs) in vivo
Authors: Cheng Changgui , Wu Zhanpo , Chen Youmin , Wu Fuhua , Li Qun , Gao Zengxin
Published: August 2021

To explore the effects of artificial joint prosthesis nanoparticles on cytotoxicity and osteogenic differentiation of Bone Marrow Stromal Cell (BMSCs). SD rats were used to isolate cells and titanium metal obtained from artificial joint revision surgery was prepared into nanoparticles
by the direct current arc plasma method. The SD rats were then divided into control group, blank group (group A: D-MEM medium+10% FBS), low concentration group (group B: 0.01 mg/mL titanium alloy particles), medium concentration group (group C: 0.05 mg/mL titanium alloy particles), high concentration
group (group D: 0.1 mg/mL titanium alloy particles plus D-MEM complete medium+10% FBS), followed by analysis of cytotoxicity and osteogenic differentiation of BMSCs. Among the three test groups, group B showed highest percentage of viable cells and group D had lowest. The percentages of viable
cells in three test groups were significantly lower and cell death rate were higher than those in the control group (P < 0.05). Titanium alloy metal particles inhibited osteogenic differentiation of BMSCs in a dose dependent manner. The cells in control group were stained and dark
brown nuclei were visible. The stained cells were almost invisible in group A, and less red-stained areas in group B, and with a small amount of cell nuclei. Artificial joint prosthesis particles had certain effects on cytotoxicity and osteogenic differentiation of BMSCs in vivo. Among
them, the high concentration of titanium alloy nanoparticles test group had the highest percentage of viable cells.
Future Summer Drying in the U.S. Corn Belt and the Role of Midlatitude Storm Tracks
Authors: Ting Mingfang , Seager Richard , Li Cuihua , Liu Haibo , Henderson Naomi
Published: August 2021

During the summer, the Midwest United States, which covers the main US corn belt, has a net loss of surface water as evapotranspiration exceeds precipitation. The net moisture gain into the atmosphere is transported out of the region to northern high latitudes through transient eddy moisture fluxes. How this process may change in the future is not entirely clear despite the fact that the corn belt region is responsible for a large portion of the global supply of corn and soybeans. We find that increased CO2 and the associated warming increases evapotranspiration. while precipitation reduces in the region leading to further reduction in precipitation minus evaporation (P-E) in the future. At the same time, the poleward transient moisture flux increases leading to enhanced atmospheric moistures export from the corn belt region. However, storm track intensity is generally weakened in the summer due to reduced north-south temperature gradient associated with amplified warming in the midlatitudes. The intensified transient eddy moisture transport as storm track weakens can be reconciled by the stronger mean moisture gradient in the future. This is found to be caused by the climatological low-level jet transporting more moisture into the Great Plains region due to the thermodynamic mechanism under warmer conditions. Our results, for the first time, show that in the future, the US Midwest corn belt will experience more hydrological stress due to intensified transient eddy moisture export leading to drier soils in the region.
A Comparison of Tropical Cyclone Projections in a High-resolution Global Climate Model and from Downscaling by Statistical and Statistical-deterministic Methods
Authors: Jing Renzhi , Lin Ning , Emanuel Kerry , Vecchi Gabriel , Knutson Thomas R.
Published: August 2021

In this study, we investigate the response of tropical cyclones (TCs) to climate change by using the Princeton environment-dependent probabilistic tropical cyclone (PepC) model and a statistical-deterministic method to downscale TCs using environmental conditions obtained from the Geophysical Fluid Dynamics Laboratory (GFDL) High-resolution Forecast-oriented Low Ocean Resolution (HiFLOR) model, under the Representative Concentration Pathway 4.5 (RCP4.5) emissions scenario for the North Atlantic basin. The downscaled TCs for the historical climate (1986-2005) are compared with those in the mid- (2016-35) and late-twenty-first century (2081-2100). The downscaled TCs are also compared with TCs explicitly simulated in HiFLOR. We show that while significantly more storms are detected in HiFLOR towards the end of the twenty-first century, the statistical-deterministic model projects a moderate increase in TC frequency, and PepC projects almost no increase in TC frequency. The changes in storm frequency in all three datasets are not significant in the mid-twenty-first century. All three project that storms will become more intense and the fraction of major hurricanes and Category 5 storms will significantly increase in the future climates. However, HiFLOR projects the largest increase in intensity while PepC projects the least. The results indicate that HiFLOR’s TC projection is more sensitive to climate change effects and statistical models are less sensitive. Nevertheless, in all three datasets, storm intensification and frequency increase lead to relatively small changes in TC threat as measured by the return level of landfall intensity.
Effects of Tropical Sea Surface Temperature Variability on Northern Hemisphere Tropical Cyclone Genesis
Authors: Li Shuo , Mei Wei , Xie Shang-Ping
Published: August 2021

This study quantifies the contributions of tropical sea surface temperature (SST) variations during the boreal warm season to the interannual-to-decadal variability in tropical cyclone genesis frequency (TCGF) over the Northern Hemisphere ocean basins. The first seven leading modes of tropical SST variability are found to affect basinwide TCGF in one or more basins, and are related to canonical El Niño–Southern Oscillation (ENSO), global warming (GW), the Pacific meridional mode (PMM), Atlantic multidecadal oscillation (AMO), Pacific decadal oscillation (PDO), and the Atlantic meridional mode (AMM). These modes account for approximately 58%, 50%, and 56% of the variance in basinwide TCGF during 1969–2018 over the North Atlantic (NA), northeast Pacific (NEP), and northwest Pacific (NWP) Oceans, respectively. The SST effect is weak on TCGF variability in the north Indian Ocean. The SST modes dominating TCGF variability differ among the basins: ENSO, the AMO, AMM, and GW are dominant for the NA; ENSO and the AMO for the NEP; and the PMM, interannual AMO, and GW for the NWP. A specific mode may have opposite effects on TCGF in different basins, particularly between the NA and NEP. Sliding-window multiple linear regression analyses show that the SST effects on basinwide TCGF are stable in time in the NA and NWP, but have strengthened since the 1990s in the NEP. The SST effects on local TC genesis and occurrence frequency are also explored, and the underlying physical mechanisms are examined by diagnosing a genesis potential index and its components.
Stochastic aeroelastic analysis of laminated composite plate with variable fiber spacing
Authors: Sharma Narayan , Swain Prasant Kumar , Maiti Dipak Kumar , Singh Bhrigu Nath
Published: August 2021

In this paper, the dynamic and aeroelastic analysis of variable fiber spacing composite (VFSC) laminated plates are carried out. The effects and benefits of changing the fiber distribution pattern on natural frequency and mode shape are explored taking various boundary conditions. Taking cantilever boundary condition flutter characteristics of VFSC plate with different fiber distribution patterns are compared. Further stochasticity of flutter velocity due to randomness in material properties that could arise due to complex manufacturing and fabrication process of VFSC laminates is investigated. The perturbation technique is implemented to perform the stochastic as well as reliability analysis. Various parametric studies are conducted to check the accuracy and efficiency of perturbation technique, by comparing the results with that of Monte Carlo simulation and the first-order reliability method.
Change in Life Attitudes During Inpatient Psychosomatic Treatment
Authors: Valdés-Stauber Juan , Kämmerle Helen , Bachthaler Susanne
Published: August 2021

Objectives: This study’s primary aim was to investigate whether meaning-based attitudes to life change during inpatient psychosomatic treatment and the factors influencing the extent of this change. Method: This prospective study ( N = 138) was designed as a naturalistic observation. The effectiveness of treatment was investigated through pre–post comparisons of clinical variables and life attitudes (Life Attitude Profile–Revised) using bivariate tests. Factors influencing the extent of changes in life attitudes were investigated using multivariate regression models. Results: Regarding clinical variables, a small but significant improvement in life attitudes was found, with effect sizes ranging from 0.19 to 0.58. Neuroticism correlated negatively with life attitudes at admission but not significantly with the extent of change in life attitudes. In multivariate models, the extent of the therapeutic relationship and neuroticism correlated positively with the extent of improvement in coherence and self-efficacy. The improvement in self-efficacy was associated with an improvement in life attitudes. Discussion: Although life attitudes are robust characteristics of a person, they change during a hospital psychosomatic treatment, similar to the clinical improvement of symptoms. However, the association between the two is weak. People with stronger neuroticism experience a greater increase in life meaning during hospitalization.