bluuebunny/crossref_metadata_2025 huggingface dataset:
Pelatihan Implementasi Komunikasi Efektif plus Pemasaran Sosial 7P (KEPPS 7P) dalam Pelayanan Kesehatan di Rumah Sakit Setia Mitra Jakarta Selatan
Authors: Rindu Rindu , Novita Astrid , Sihura Sancka Stella Ganiasnda , GP Lazuardi , Reni Reni
Published: December 2023

Komunikasi efektif dan efisien dalam layanan kesehatan memiliki peran yang vital bagi keselamatan pasien. Tidak hanya dalam menyampaikan informasi pelayanan yang tersedia namun juga saat harus memberikan kabar kurang menyenangkan. Hal ini berdampak pada penurunan kualitas mutu pelayanan rumah sakit sehingga perlu adanya patient care yang optimal yang akan berdampak pada kepuasan pasien. Didalam mewujudkan komunikasi efektif di rumah sakit, setiap staf perlu mengimplementasikan konsep bauran pemasaran 7P yang memiliki 7 elemen yang terdiri dari product, price, promotion, place, people, process serta physical evidence. Berdasar 7 elemen tersebut maka para staf rumah sakit diharapkan bisa mengimplementasikan komunikasi efektif di setiap unit mereka. Pengabdian kepada masyarakat ini bekerjasama dengan Rumah Sakit Setia Mitra Jakarta Selatan. Adapun tujuan dari kegiatan ini adalah diharapkan dapat meningkatkan kompetensi yaitu mampu menjelaskan Teknik Komunikasi, mampu menerapkan Etika Dalam Penampilan Kerja, mampu menerapkan Etika Komunikasi, mampu melaksanakan Manajemen Konfik, mampu melaksanakan Penanganan Komplain, mampu melaksanakan Komunikasi Efektif dan Komunikasi SBAR, serta mampu menerapkan bauran pemasaran 7P. Pengabdian masyarakat berupa pelatihan komunikasi efektif dan pemasaran sosial 7P menunjukkan hasil yang efektif dimana terdapat nilai perbedaan mean 1,08 menunjukkan terdapat selisih rata-rata nilai pengetahuan sebelum (15.81) dan sesudah (16.89) dimana tujuan daripada edukasi dan pelatihan sudah tercapai, yakni perubahan pengetahuan, sikap dan tingkah laku individu, keluarga, kelompok khusus, dan masyarakat.
Upaya Peningkatan Kesehatan Masyarakat Melalui Pengetahuan Dan Pengobatan PTM Di Desa Cikeas Udik
Authors: Liana Duta , Yuliati Yuliati , Pamungkas Rian Adi
Published: December 2023

Masalah kesehatan fisik masih menjadi ancaman kesehatan masyarakat terutama pada penyakit tidak menular (PTM) misalnya hipertensi, stroke, penyakit jantung dan diabetes mellitus. Secara global, 41 juta orang meninggal setiap tahunnya karena PTM dimana 17 juta meninggal sebelum usia 70 tahun. Peningkatan prevalensi PTM mengindikasikan perlunya mengubah pola hidup sehat. Kegiatan skrining, penyuluhan, dan pengobatan dapat menjadi alternatif pemberdayaan masyarakat. Kegiatan dilaksanakan tanggal 30 September-1 Oktober 2023   di Desa Cikeas Udik, Kabupaten Bogor. Hasil skrining sebanyak 93 orang (88,6%) eligible mendapatkan pengobatan dimana sebagian besar berusia ≥ 46 tahun (52,7%). Lima penyakit terbanyak adalah hipertensi (26,8%), myalgia (13,8%), DM (9,7%), ISPA (7,3%), dan dyspepsia (7,3%). Dalam kegiatan ini diberikan penyuluhan dan edukasi kepada masyarakat meliputi definisi, faktor risiko, pencegahan, pengobatan, penanganan penyakit, pola hidup sehat, olahraga, menjaga pola dan jenis makanan yang dikonsumsi. Kemudian dilaksanakan pengobatan oleh dokter dengan pengobatan terbanyak pada penderita hipertensi, myalgia, dan DM. Harapannya kegiatan ini dapat menjadi upaya peningkatan kesehatan masyarakat dengan meningkatknya pengetahuan dan kesadaran akan pentingnya pencegahan dan pengobatan penyakit tidak menular, khususnya hipertensi dan diabetes mellitus sehingga dapat terkontrol dan menghindari komplikasi. Diperlukan juga keterlibatan aktif kader dan puskesmas setempat dalam meneruskan edukasi kepada warga didesanya tentang penyakit hipertensi dan diabetes mellitus.
New Method of Measuring the Depth of Soil Tillage
Authors:   Rosinformagrotech, Podolskaya E.E.
Published: December 2023

The authors propose a new method for measuring the depth of soil cultivation by tillage machines based on a system of inertial position sensors. The block diagram and design of the inertial sensor for measuring the depth of travel of the working tools are substantiated. To test the effectiveness of the new method the bench that simulates the immersion of the working tools of soil-cultivating machines to different depths has been developed. The proposed method was examined on the bench.
Experimental Studies of Engine Crankcase Gas Consumption D-243 With Varying Degrees of Wear of the Cylinder-piston Group
Authors:   RGAU-MSHA named after K.A. Timiryazev, Didmanidze O.N. , Suchkov A.I. ,   RGAU-MSHA named after K.A. Timiryazev, Devyanin S.N. ,   RGAU-MSHA named after K.A. Timiryazev, Guzalov A.S. ,   RGAU-MSHA named after K.A. Timiryazev, Bugaev A.V. ,   RGAU-MSHA named after K.A. Timiryazev, Kurylenko A.V. ,   RGAU-MSHA named after K.A. Timiryazev
Published: December 2023

The methodology and results of the experimental studies of crankcase gas consumption in diesel engines with varying degrees of wear of the cylinder-piston group (CPG) are presented. It is shown that the rotation speed has a significant influence on the crankcase gas consumption and the load has an insignificant influence on it. It is recommended to use the idle mode at the nominal or maximum rotation speed as a diagnostic test mode to assess the technical condition of the CPG.
Reducing Electricity Losses at 10/0.4 kV Transformer Substations by Replacing one Transformer With two and Using Photovoltaic Arrays
Authors:   FGBNU FNATs VIM, Vinogradov A.V. , Vinogradova A.V. ,   FGBNU FNATs VIM, Lansberg A.A. ,   FGBNU FNATs VIM, Konkin D.V. ,   FGBNU FNATs VIM
Published: December 2023

Using the example of rural electrical networks in the Oryol region, it was revealed that transformers are loaded at 20-25%. The use of photovoltaic arrays (PV) in the grid structure leads to an additional seasonal reduction in load. A method has been proposed to reduce electricity losses in transformer substations by replacing one transformer with two of lower power. An assessment was made of the reduction in losses and their cost when using the proposed method, including the use of photovoltaic arrays.
Experience in Implementing the FSTDP Subprogram “Development of Selection and Seed production of Sugar beets in the Russian Federation”
Authors:   Rosinformagrotech, Korolkova A.P.
Published: December 2023

The results of the implementation of the subprogram “Development of selection and seed production of sugar beets in the Russian Federation” of the Federal Scientific and Technical Program for the Development of Agriculture for 20172030 (FSTDP) are presented. The authors consider the created hybrids, their yield and sugar content in different regions, the paths for improving the sugar beet seed production system and the measures of state support for the production of domestically selected seeds.
Regulatory Framework for Testing Sugar Beet Harvesting Machines
Authors: Podolskaya E.E.
Published: December 2023

Проанализирована нормативно-методическая документация, применяемая при испытании машин для уборки сахарной свеклы. Приведены данные о действующих и требующих переработки стандартах различного уровня, используемых при оценке свеклоуборочной техники. Представлены основные положения разрабатываемого проекта стандарта организации, устанавливающего современные требования к показателям назначения, надежности и условиям испытаний свеклоуборочных комбайнов, корнеуборочных и ботвоуборочных машин, свеклоподъемников, очистителей головок корней, машин и приспособлений для уборки корнеплодов маточной свеклы.
Testing the Indicators of Unevenness and Instability of the Total Seeding of an Experimental Seeder for Lawn Grass
Authors:   RGAU-MSHA named after K.A. Timiryazev, Plyaka V.I. , Sergeeva N.A. ,   RGAU-MSHA named after K.A. Timiryazev
Published: December 2023

The article deals with the results of testing the indicators of uneven seeding across the working width and the instability of the overall seeding with an experimental lawn grass seeder in the areas that have a complex configuration. The seeder equipped with a roller feed is capable of providing uniform seeding both in straight and curved motion.
Proximate Composition and Mineral Content of Edible Cuttlefish (Sepiella Inermis), Squid (Uroteuthis Duvauceli) and Octopus (Cistopus Taiwanicus) of Bangladesh
Authors: Ahmed Md Sagir , Arfin Noor Aida , Mahjabin Mysha , Datta Sujan Kumar
Published: December 2023

Cephalopods are valuable in fisheries and are consumed as seafood in various cuisines around the world. A study was conducted to know the proximate compositions (protein, ash, fat, carbohydrate and moisture) and minerals (calcium, phosphorus and iron) of cephalopods (octopuses, squids, and cuttlefishes) of Bangladesh. Three species, cuttlefish (Sepiella inermis), squid (Uroteuthis duvauceli) and octopus (Cistopus taiwanicus) were selected on the basis of their availability. The average protein was estimated 16.14%, 15.04%, and 14.68% for Cuttlefish, Squid, and Octopus, respectively whereas the amount of carbohydrate was 0.59%, 0.71%, and 0.53% for the three species. The ANOVA test of the findings of the proximate components showed no significant differences among the three groups (p < 0.05). All the three cephalopods have shown quite the same amount of protein (16.14%, 15.04%, 14.68%) as in commonly consumed fish (rui, catla) and shrimp. The findings suggest that these organisms serve as outstanding sources of protein while containing minimal amounts of fat. The lower amount of fat of cephalopods also proves them leaner than other groups in the comparison. Thus, cephalopods can be a promising source of animal protein in Bangladesh. Both the octopus and cuttlefish showed a good amount of calcium and phosphorus, while the squid proved to be an ideal source of iron. This study proposes to investigate the potential of other cephalopods in the human diet further by undertaking a more thorough analysis that includes all necessary micro and macronutrients.
Bioresearch Commu. 10(1): 1420-1423, 2024 (January)
The Influence of Tool Rotational Speed on Mechanical Properties of Friction Stir Welded Dissimilar AA5083-H112/AA6061-T6 Joints
Authors: Permana Andrian , Ilman Mochammad Noer
Published: December 2023

The relatively new and innovative welding technique known as friction stir welding (FSW) has found widespread application in the automotive, railway, and aircraft industries. Due to engineering and financial considerations, welding of dissimilar metals is frequently carried out in these industries. During the friction stir welding process, three tool rotational speeds—910, 1500, and 2280 rpm—were utilized, while the welding speed remained constant at 30 mm/min. Several experimental works, including fractography, tensile tests, and observations of the microstructure, were carried out following welding. Results showed that ultimate tensile strength (UTS) and yield strength (YS) expanded as the tool rotational speed was expanded and the best UTS and YS, typically 228 MPa and 156 MPa at the speed of 2280 rpm. The precipitation of AA6061-T6 in the stir zone (SZ) and the increased degree of mixing were linked to the improved weld strengths.
Motivasi belajar siswa SMP dalam pembelajaran jarak jauh PJOK selama pandemi covid-19
Authors: Sukmawati Diana , Kusumawati Mia
Published: December 2023

The pandemic is a blow to all mankind, everything changes from lifestyles to learning models. Learning physical education sports and health is one of the materials that is usually done outdoors but with the pandemic, teachers are required to further develop learning through various kinds of networks available. This study aims to determine the learning motivation of junior high school students in PJOK distance learning during the COVID-19 accordance with the predetermined targets, teaching and learning activities need to be arranged in a good program. Qualitative descriptive research is a research method that utilizes qualitative data and is described descriptively intended to get a picture or analyze the motivation of junior high school students in PJOK distance learning during the COVID-19 pandemic. The results of research on student learning motivation online, the average percentage of student learning motivation is 64% and the supporting factors during the COVID-19 pandemic are 60%, including the lack category. Distance learning currently implemented by the government related to the COVID-19 virus cannot be said to be successful, considering that the results of research in the north bekasi sub-district resulted in a percentage value that each fell into the category of less.
Kontribusi daya ledak otot tungkai terhadap kemampuan tendangan samping atlet pencak silat Kuciang Putiah Harimau Campo Padang Panjang
Authors: Hafid Fathurrahman , Firdaus Firdaus
Published: December 2023

The problem with this research is that there are still many fighters from the Kuciang Putiah Harimau Campo College who experience defeat. The purpose of this study was to analyze the direct effects of leg muscle explosive in Pencak Silat athletes Kuciang Putiah Harimau Campo, Padang Panjang City. The method used in this study is a quantitative method using the Path Analysis technique. The population in this study were Pencak Silat athletes Kuciang Putiah Harimau Campo Padang Panjang City, totaling 61 people. In this study, the sample was determined using a purposive sampling technique, amounting to 25 people. Based on the findings and discussion, it can be concluded that there is a direct and significant effect of leg muscle explosive power on the side kick ability of the Kuciang Putiah Pencak Silat Athlete, the Harimau Campo Padang Panjang.
Integrating sport education model and the athletics challenges approach for transformative physical education in Indonesian Middle Schools
Authors: Komalasari Rita
Published: December 2023

Physical education (PE) in Indonesian middle schools faces challenges, including outdated curricula and limited teacher development. This study investigates integrating the Sport Education model and Athletics Challenges approach to enhance PE. Sport Education aims to develop competent, literate, and enthusiastic sportspeople, while Athletics Challenges promotes inclusive group learning, self-assessment, and authentic athletic events. Literature analysis reveals positive outcomes, but lacks Indonesian context. This paper addresses gaps by proposing integration and analyzing it in the Indonesian middle school setting. Cultural nuances, practical experiences, and literature insights are explored. The study contributes novel insights by offering an integrated pedagogical model, cultural adaptation, teacher collaboration, student-centered learning, leadership development, and implications for policy and practice. The Ecological Systems Theory guides the analysis, providing a holistic framework to address diverse influences at micro, meso, exo, macro, and chrono levels. By merging pedagogical models, considering cultural contexts, and applying the theory, this study contributes to enriching PE and enhancing education in Indonesia.
Profil indeks massa tubuh dan daya tahan kardiovaskular (VO₂Max) peserta ekstrakurikuler futsal Sekolah Menengah Atas
Authors: Muzakki Roihan Hafizh , Hariyoko Hariyoko
Published: December 2023

Futsal merupakan olahraga yang termasuk dalam aktivitas fisik kategori olahraga berat yang bersifat dinamis. Untuk menghasilkan pemain yang berkualitas harus memperhatikan salah satunya indeks massa tubuh. Selain itu daya tahan kardiovaskular yang baik wajib dimiliki, sebab berpengaruh sebagai penunjang pemain dalam permainan. Berdasarkan uraian yang dipaparkan, maka sangat penting mengetahui profil indeks massa tubuh dan daya tahan kardiovaskular untuk menjadi bahan evaluasi dan untuk menunjang prestasi. Penelitian ini memiliki tujuan untuk mengetahui dan mengkaji profil indeks massa tubuh dan daya tahan kardiovaskular peserta ekstrakurikuler futsal SMA Negeri 1 Rejoso. Penelitian ini menggunakan metode survei jenis deskriptif kuantitatif. Populasi dalam penelitian ini berjumlah 40 dengan 20 peserta diambil sebagai sampel. Berdasarkan hasil pengukuran diperoleh hasil indeks massa tubuh peserta ekstrakurikuler futsal yaitu 3 peserta (15%) kategori kekurangan berat badan tingkat berat, 3 peserta (15%) kategori kekurangan berat badan tingkat ringan, 13 peserta (65%) kategori berat badan ideal dan 1 peserta (5%) kategori kelebihan berat badan tingkat ringan. Sedangkan daya tahan kardiovaskular 10 peserta (50%) termasuk dalam kategori sangat kurang, 7 peserta (35%) kategori kurang, dan 3 peserta (15%) kategori sedang. Dengan demikian dapat disimpulkan bahwa indeks massa tubuh tergolong kategori berat badan ideal sedangkan daya tahan kardiovaskular tergolong kategori sangat kurang.
An Intelligent Control Method for Servo Motor Based on Reinforcement Learning
Authors: Gao Depeng , Wang Shuai , Yang Yuwei , Zhang Haifei , Chen Hao , Mei Xiangxiang , Chen Shuxi , Qiu Jianlin
Published: December 2023

Servo motors play an important role in automation equipment and have been used in several manufacturing fields. However, the commonly used control methods need their parameters to be set manually, which is rather difficult, and this means that these methods generally cannot adapt to changes in operation conditions. Therefore, in this study, we propose an intelligent control method for a servo motor based on reinforcement learning and that can train an agent to produce a duty cycle according to the servo error between the current state and the target speed or torque. The proposed method can adjust its control strategy online to reduce the servo error caused by a change in operation conditions. We verify its performance on three different servo motors and control tasks. The experimental results show that the proposed method can achieve smaller servo errors than others in most cases.
A 16-Year Single-Center Series of Trachea Resections for Locally Advanced Thyroid Carcinoma
Authors: Staubitz-Vernazza Julia I. , Schwind Sina , Lozan Oana , Musholt Thomas J.
Published: December 2023

(1) Background: Infiltration of the aerodigestive tract in advanced thyroid carcinoma determines the prognosis and quality of life. Different stages of tracheal tumor invasion require customization of the surgical concept. (2) Methods: In the period from January 2007 to January 2023, patients who underwent surgery for advanced thyroid carcinomas with trachea resections were included in a retrospective observational study. The surgical resection concepts and operation-associated complications were documented. The overall survival and post-resection survival were analyzed. (3) Results: From 2007 to 2023, at the single-center UMC Mainz, 33 patients (15 female and 18 male) underwent neck surgery with trachea resections for locally advanced thyroid carcinomas. Of these, 14 were treated with non-transmural (trachea shaving) and 19 transmural trachea resections (9 “window” resections, 6 near-circular resections, 3 sleeve resections and 1 total laryngectomy with extramucosal esophageal resection). The two-year postoperative survival rate was 82.0 percent. The two-year recurrence-free survival rate was 75.0 percent (mean follow-up period: 29.2 months). (4) Conclusions: Tracheal resections for locally advanced tumor infiltration are feasible as an element of highly individualized treatment concepts.
The Influence of Curing System on the Macroscopic Performance and Microstructure of Anti-Abrasive UHPC
Authors: Li Jinhui , Yu Zi , Xu Fang , Guo Zhijiong , Ding Qingjun
Published: December 2023

In a previous study, we utilized saturated prewet high titanium heavy slag sand to produce UHPC (ST-UHPC). ST-UHPC has high impact and abrasion resistance. For better ST-UHPC applications, we investigate the mechanism of ST-UHPC under different curing systems from the microstructure and macroscopic perspective in this paper. We prepared ST-UHPC under four maintenance conditions: 20 °C standard curing, 90 °C steam curing, 90 °C dry curing and 210 °C 2 MPa pressure steam curing. Then, we analyzed the hydration product composition, the degree of cement hydration, the C-A-S-H gel microstructure and the substitution of Al3+ for Si4+ in relation to these prepared ST-UHPCs. Compared with standard curing, dry curing at 90 °C accelerated the water evaporation and reduced the hydration degree of ST-UHPC cementite. However, pressure steam curing significantly improved the hydration degree of ST-UHPC cementing material, and increased the MCL and Al[4]/Si of C-A-S-H gel. In addition, pressure steam curing reduced the Ca/Si and promoted the conversion of C-A-S-H cementing to tobermorite. Compared with dry curing at 90 °C, pressure steam curing significantly improved the macroscopic properties of ST-UHPC. The macro-performance difference of ST-UHPC under standard curing and 90 °C steam curing is small. The reason is that steam curing caused the water to be rapidly released in the internal aggregate of ST-UHPC. This resulted in the increase of the interface between the internal aggregate of ST-UHPC and the ST-UHPC cementate. The harmful pores in the ST-UHPC matrix under steam curing were also increased. To sum up, compared with standard curing, dry curing at 90 °C weakened the mechanical properties and microstructure of ST-UHPC, but steam pressure curing increased them. The single steam curing had no significant effect on the mechanical properties and microstructure of the ST-UHPC. Therefore, non-steam and room-temperature moisturizing maintenance should be adopted for anti-abrasive UHPC.
The Impact of Surgical Delay: A Single Institutional Experience at the Epicenter of the COVID Pandemic Treatment Delays in Women with Endometrial Cancer and Endometrial Intraepithelial Hyperplasia
Authors: Seay Kieran , Katcher Arielle , Hare Maia , Kohn Nina , Juhel Hannah , Goldberg Gary L. , Frimer Marina
Published: December 2023

The spread of COVID-19 led to a lockdown in New York in March of 2020. Nonemergent surgeries were postponed, including oncologic procedures. The backlog of surgeries was addressed starting May 2020. Our goal was to examine the change in waiting times for endometrial cancer surgeries during the COVID-19 pandemic in our institution. Data on surgery incidence and waiting time was gathered for patients diagnosed with endometrial intraepithelial neoplasia and endometrial cancer. The association between days from diagnosis to surgery was adjusted for age, obesity, presence of comorbid conditions, race, smoking history and diagnosis and was examined using a general linear model. A total of 190 patients were identified for this retrospective study. Five subjects were missing information on race and were excluded from all analyses, resulting in 185 subjects in the final analyses. Mean waiting time during COVID-19 was 70.9 days (95%CI 55.0, 91.3), compared to 49.3 (95%CI 49.8, 63.8) days during the reference period. No significant associations were seen between the time and any of the clinical or demographic factors.
Investigation on Secondary Flow of Turbodrill Stator Cascade with Variable Rotary Speed Conditions
Authors: Gong Yan , Liu Yonghong , Wang Cong , Zhang Jie , He Mengyuan
Published: December 2023

There are various secondary flow types in turbodrill’s blade cascades, and all kinds of secondary flow have a significant effect on flow loss. In this paper, the stator cascade of φ160 mm turbodrill is taken as the research object, and the CFD method is used to analyze the secondary flow and its evolution. The origin and evolution mechanism of secondary flow is explained from the flow mechanism. The results show that when the working rotary speed is lower than the design rotary speed, the secondary flows are composed of suction surface separation vortex, horseshoe vortex, and passage vortex coexisting. The intensity of secondary flows increases with the decrease of rotary speed. When the working rotary speed is near the design rotary speed, the secondary flows include horseshoe vortex, passage vortex, and corner vortex. When the working rotary speed is higher than the design rotary speed, the secondary flows consist of pressure surface separation vortex and suction surface trailing edge separation vortex. Regardless of rotary speed, secondary flow intensity in the shroud region is greater than the hub region, which has a greater influence on the mainstream. In addition, compared with high rotary speeds, secondary flow intensity is greater at low rotary speeds, resulting in greater flow losses.
Energy Management Model for a Remote Microgrid Based on Demand-Side Energy Control
Authors: Benavides Dario , Arévalo Paul , Ortega Antonio Cano , Sánchez-Sutil Francisco , Villa-Ávila Edisson
Published: December 2023

The internet of things is undergoing rapid expansion, transforming diverse industries by facilitating device connectivity and supporting advanced applications. In the domain of energy production, internet of things holds substantial promise for streamlining processes and enhancing efficiency. This research introduces a comprehensive monitoring and energy management model tailored for the University of Cuenca’s microgrid system, employing internet of things and ThingSpeak as pivotal technologies. The proposed approach capitalizes on intelligent environments and employs ThingSpeak as a robust platform for presenting and analyzing data. Through the integration of internet of things devices and sensors, the photovoltaic system’s parameters, including solar radiation and temperature, are monitored in real time. The collected data undergo analysis using sophisticated models and are presented visually through ThingSpeak, facilitating effective energy management and decision making. The developed monitoring system underwent rigorous testing in a laboratory microgrid setup, where the photovoltaic system is interconnected with other generation and storage systems, as well as the electrical grid. This seamless integration enhances visibility and control over the microgrid’s energy production. The results attest to the successful implementation of the monitoring system, highlighting its efficacy in improving the supervision, automation, and analysis of daily energy production. By leveraging internet of things technologies and ThingSpeak, stakeholders gain access to real-time data, enabling them to analyze performance trends and optimize energy resources. This research underscores the practical application of internet of things in enhancing the monitoring and management of energy systems with tangible benefits for stakeholders involved.
A Review of Modern Computational Techniques and Their Role in Power System Stability and Control
Authors: Pavon Wilson , Jaramillo Manuel , Vasquez Juan C.
Published: December 2023

This paper attempts to elucidate the transformative integration of computational techniques within power systems, underscoring their critical role in enhancing system modeling, control, and the efficient integration of renewable energy. It breaks down the two-sided nature of technological progress, highlighting both gains in operational efficiency and new challenges such as real-time processing, data management, and cybersecurity. Through meticulous analysis of query-based research patterns and mathematical frameworks, this study delves into the balancing act between specificity and breadth in scholarly inquiries while evaluating the impact and evolution of research trends through citation analysis. The convergence of interests and transient research trends is evident, particularly in Artificial Intelligence and optimization. This comprehensive narrative anticipates a sophisticated trajectory for power systems, advocating for continuous innovation and strategic research to foster sustainable, resilient, and intelligent energy networks.
Ternary Fe- or Mo-Au-Ni/GDC as Candidate Fuel Electrodes for the Internal Dry Reforming of CH4: Physicochemical and Kinetic Investigation
Authors: Ioannidou Evangelia , Neophytides Stylianos G. , Niakolas Dimitrios K.
Published: December 2023

The present study deals with the physicochemical and catalytic/kinetic investigation of Fe, Au, Fe-Au, and Mo-Au modified Ni/GDC electrocatalysts towards their performance for the DRM, RWGS, and CH4 decomposition reactions. For this purpose, Au-NiO/GDC (where Au = 1 or 3 wt.%), Fe-NiO/GDC (where Fe = 0.5 or 2 wt.%), 0.5Fe-3Au-NiO/GDC, and 0.4Mo-3Au-NiO/GDC were synthesized via deposition (co-) precipitation. There is discussion on the structural properties of the electrocatalysts on the oxidized and reduced state, as well as their use as electrolyte-supported (half) cells. A key remark after H2-reduction is the formation of binary or ternary solid solutions. Ni/GDC was the most active for the catalytic CO2 reforming of CH4 and the CH4 decomposition reactions and as a result the most prone to carbon deposition. On the other hand, the modified 3Au-Ni/GDC, 0.5Fe-3Au-Ni/GDC, and 0.4Mo-3Au-Ni/GDC exhibited the following properties: (i) the highest Ea,app for the non-desired RWGS reaction, (ii) high tolerance to carbon formation due to lower activity for the CH4 decomposition, and (iii) were also less active for H2 and CO production. Finally, 0.4Mo-3Au-Ni/GDC seems to perform the DRM reaction through a different mechanism when compared to Ni/GDC. Overall, the above three samples are proposed as potential fuel electrodes for further electrocatalytic measurements for the SOFC internal DRM process.
Driving Characteristics Analysis Method Based on Real-World Driving Data
Authors: Lee Sangho , Eom Injae , Lee Beomho , Won Janghyeok
Published: December 2023

All vehicles available for sale undergo certification tests mandated by law, and their certified fuel efficiency from these tests is indicated and disclosed. However, to address discrepancies between the certified fuel efficiency and actual driving conditions, more sophisticated certified modes, post-certification systems, and real-world driving tests have been introduced to complement the fuel efficiency certification system. The incorporation of a real-world driving mode, similar to certification modes, in vehicle research and development is of paramount importance from a directional perspective. To achieve this, various methods of configuring real-world driving modes have been proposed and applied in research. However, the validation of the correlation between fuel efficiency in real-world driving modes and certified driving modes is relatively limited. This study aimed to construct real-road driving cycles that are similar to the federal test procedure (FTP-75) and highway fuel economy test (HWFET) certification modes to determine the differences between the driving characteristics of the certification modes and real-road driving. The present study employed the commonly used relative positive acceleration analysis method along with a segmented short-trip technique for analysis. Additionally, variables such as fuel consumption and driving time were utilized to diversify our analytical methods. Test Routes A and B were configured for comparison with the fuel efficiency certification mode. An analysis of the relative positive acceleration (RPA) in both the test routes and certification mode confirmed that Test Route B, reflecting the actual driving patterns, closely follows the RPA distribution of the certification mode. Additionally, the fuel consumption for each short trip on each route was graphically represented, addressing aspects where determining the driving characteristics based solely on the RPA, such as the road grade, was difficult.
Leaf Area Estimation of Yellow Oleander Thevetia peruviana (Pers.) K. Schum Using a Non-Destructive Allometric Model
Authors: Rodriguez-Paez Luis Alfonso , Jarma-Orozco Alfredo , Jaraba-Navas Juan de Dios , Pineda-Rodriguez Yirlis Yadeth , Pompelli Marcelo F.
Published: December 2023

The resurgence of interest in medicinal plants and their potential in pharmaceuticals has driven research into harnessing bioactive compounds for innovative treatments. This study proposes an accurate and non-destructive method to estimate leaf area (LA) for Thevetia peruviana through linear measurements of the leaf length (L), the leaf width (W), or the product of the leaf length and width (LW). The study encompasses comprehensive analyses of leaf dimensions collected during different seasons (rainy and dry season), employing linear and non-linear regression models to predict LA. Among the diverse models tested, non-linear equations emerged as superior predictors of LA, surpassing simpler linear models. However, in the rigorous selection process, the equations were linear with the intercept and power model, meeting the requirements for accurate and unbiased LA estimation. Despite the competence of these models, distinguishing between them based on evaluation criteria proved inconclusive. Following the principle of simplicity, equations linear with the intercept [LA = 0.284 + 0.766 × (LW)] are preferred as power models [LA = 0.914 × (LW)0.939] and are recommended as an optimal and practical choice for estimating T. peruviana LA in field experiments. The investigation emphasizes the importance of a robust approach to LA estimation, offering crucial insights into the allometric relationships and facilitating informed agricultural decisions. This comprehensive study advances our understanding of T. peruviana and contributes to the broader discourse on accurate and efficient leaf area estimation techniques in plant biology and agriculture.
Latent Autoregressive Student-t Prior Process Models to Assess Impact of Interventions in Time Series
Authors: Toman Patrick , Ravishanker Nalini , Lally Nathan , Rajasekaran Sanguthevar
Published: December 2023

With the advent of the “Internet of Things” (IoT), insurers are increasingly leveraging remote sensor technology in the development of novel insurance products and risk management programs. For example, Hartford Steam Boiler’s (HSB) IoT freeze loss program uses IoT temperature sensors to monitor indoor temperatures in locations at high risk of water-pipe burst (freeze loss) with the goal of reducing insurances losses via real-time monitoring of the temperature data streams. In the event these monitoring systems detect a potentially risky temperature environment, an alert is sent to the end-insured (business manager, tenant, maintenance staff, etc.), prompting them to take remedial action by raising temperatures. In the event that an alert is sent and freeze loss occurs, the firm is not liable for any damages incurred by the event. For the program to be effective, there must be a reliable method of verifying if customers took appropriate corrective action after receiving an alert. Due to the program’s scale, direct follow up via text or phone calls is not possible for every alert event. In addition, direct feedback from customers is not necessarily reliable. In this paper, we propose the use of a non-linear, auto-regressive time series model, coupled with the time series intervention analysis method known as causal impact, to directly evaluate whether or not a customer took action directly from IoT temperature streams. Our method offers several distinct advantages over other methods as it is (a) readily scalable with continued program growth, (b) entirely automated, and (c) inherently less biased than human labelers or direct customer response. We demonstrate the efficacy of our method using a sample of actual freeze alert events from the freeze loss program.
KMT2D Deficiency Causes Sensorineural Hearing Loss in Mice and Humans
Authors: Kalinousky Allison J. , Luperchio Teresa R. , Schrode Katrina M. , Harris Jacqueline R. , Zhang Li , DeLeon Valerie B. , Fahrner Jill A. , Lauer Amanda M. , Bjornsson Hans T.
Published: December 2023

Individuals with Kabuki syndrome type 1 (KS1) often have hearing loss recognized in middle childhood. Current clinical dogma suggests that this phenotype is caused by frequent infections due to the immune deficiency in KS1 and/or secondary to structural abnormalities of the ear. To clarify some aspects of hearing loss, we collected information on hearing status from 21 individuals with KS1 and found that individuals have both sensorineural and conductive hearing loss, with the average age of presentation being 7 years. Our data suggest that while ear infections and structural abnormalities contribute to the observed hearing loss, these factors do not explain all loss. Using a KS1 mouse model, we found hearing abnormalities from hearing onset, as indicated by auditory brainstem response measurements. In contrast to mouse and human data for CHARGE syndrome, a disorder possessing overlapping clinical features with KS and a well-known cause of hearing loss and structural inner ear abnormalities, there are no apparent structural abnormalities of the cochlea in KS1 mice. The KS1 mice also display diminished distortion product otoacoustic emission levels, which suggests outer hair cell dysfunction. Combining these findings, our data suggests that KMT2D dysfunction causes sensorineural hearing loss compounded with external factors, such as infection.
Methodological Considerations in Longitudinal Analyses of Microbiome Data: A Comprehensive Review
Authors: Lyu Ruiqi , Qu Yixiang , Divaris Kimon , Wu Di
Published: December 2023

Biological processes underlying health and disease are inherently dynamic and are best understood when characterized in a time-informed manner. In this comprehensive review, we discuss challenges inherent in time-series microbiome data analyses and compare available approaches and methods to overcome them. Appropriate handling of longitudinal microbiome data can shed light on important roles, functions, patterns, and potential interactions between large numbers of microbial taxa or genes in the context of health, disease, or interventions. We present a comprehensive review and comparison of existing microbiome time-series analysis methods, for both preprocessing and downstream analyses, including differential analysis, clustering, network inference, and trait classification. We posit that the careful selection and appropriate utilization of computational tools for longitudinal microbiome analyses can help advance our understanding of the dynamic host–microbiome relationships that underlie health-maintaining homeostases, progressions to disease-promoting dysbioses, as well as phases of physiologic development like those encountered in childhood.
Adaptation of an eHealth Intervention: iSupport for Carers of People with Rare Dementias
Authors: Naunton Morgan Bethan , Windle Gill , Lamers Carolien , Brotherhood Emilie , Crutch Sebastian
Published: December 2023

‘iSupport’ is an online psychoeducation and skills development intervention created by the World Health Organisation to support people with dementia. This project adapted iSupport for carers of people with rare dementias (iSupport RDC), creating a new resource to support the health and wellbeing of this underserved population. The adaptation involved three phases: (1) Co-design methods to generate preliminary adaptations; (2) Analysis of phase one findings informing adaptations to iSupport to develop; iSupport RDC; (3) Post-adaptation survey to ascertain participant agreement with the adaptations in iSupport RDC. Fourteen participants contributed, resulting in 212 suggested adaptations, of which 94 (92%) were considered practical, generalisable, and aligned with iSupport principles. These adaptations encompassed content and design changes, including addressing the challenges of rare dementias (PCA, PPA, LBD, and FTD). iSupport RDC represents a significant adaptation of the WHO iSupport intervention. Its tailored nature acknowledges the unique needs of people caring for someone with a rare dementia, improving their access to specialised resources and support. By extending iSupport to this population, it contributes to advancing dementia care inclusivity and broadening the understanding of rare dementias. A feasibility study is underway to assess iSupport RDCs acceptability, with prospects for cultural adaptations to benefit carers globally.
The Bmtret1 Gene Family and Its Potential Role in Response to BmNPV Stress in Bombyx mori
Authors: Lin Mingjun , Qian Yixuan , Chen Enxi , Wang Mengjiao , Ouyang Gui , Xu Yao , Zhao Guodong , Qian Heying
Published: December 2023

Trehalose is a non-reducing disaccharide and participates in physiological activities such as organ formation, energy metabolism, and stress resistance in insects. The Bmtret1 gene family is mainly involved in in the sugar metabolism of silkworm. In the present study, phylogenetic analysis divided 21 Bmtret1 orthologs into three clades. These genes are equally distributed on the nine chromosomes. The cis-elements in the promoter regions of Bmtret1s indicated the possible function of Bmtret1s in response to hormones and environmental stimulus. The qPCR analysis showed the significantly different expression levels of Bmtret1s in different tissues and organs, indicating possible functional divergence. In addition, most Bmtret1s showed disturbed expression levels in response to silkworm nuclear polyhedrosis virus (BmNPV) stresses. Our results provide a clue for further functional dissection of the Tret1s in Bombyx mori and implicate them as potential regulators of antiviral responses.
Evaluating Serum Calcium and Magnesium Levels as Predictive Biomarkers for Tuberculosis and COVID-19 Severity: A Romanian Prospective Study
Authors: Cioboata Ramona , Vasile Corina Maria , Bălteanu Mara Amalia , Georgescu Dragos Eugen , Toma Claudia , Dracea Amelia Sanda , Nicolosu Dragos
Published: December 2023

In Romania, the highest incidence of tuberculosis (TB) within the European Union was reported in 2020, highlighting a significant health challenge. This is compounded by the COVID-19 pandemic, which has severely impacted healthcare services, including TB management. Both TB and COVID-19, diseases with considerable morbidity and mortality, have shown potential links to electrolyte imbalances. We conducted a prospective study at Victor Babes Hospital, Romania on 146 patients (74 with TB, 72 with COVID-19) between December 2021 and July 2023. This study assessed correlations between disease severity and serum calcium and magnesium levels, as well as pulmonary function. Adult patients with confirmed diagnoses and comprehensive medical records were included, excluding those with chronic respiratory diseases or unrelated electrolyte imbalances. Statistical analysis utilized the Kruskal–Wallis test and Dunn’s procedure for non-normally distributed data. Low serum calcium and magnesium levels were significantly correlated with severe forms of TB and COVID-19, suggesting their potential as biomarkers of disease progression. Patients with more severe TB (i.e., multiple cavities) exhibited significantly lower serum calcium (p = 0.0049) and magnesium levels (p = 0.0004). ROC analysis revealed high AUC values for serum calcium and serum magnesium in predicting COVID-19 severity, indicating their potential as biomarkers. This study demonstrates a significant association between lower serum calcium and magnesium levels and increased TB severity. Similarly, these electrolytes show promise as predictive markers for COVID-19 severity. These findings could serve as biomarkers for predicting the severity of TB and COVID-19, offering potential utility in clinical decision-making.
New Brassinosteroid Analogs with 23,24-Dinorcholan Side Chain, and Benzoate Function at C-22: Synthesis, Assessment of Bioactivity on Plant Growth, and Molecular Docking Study
Authors: Aitken Vanessa , Diaz Katy , Soto Mauricio , Olea Andrés F. , Cuellar Mauricio A. , Nuñez Maria , Espinoza-Catalán Luis
Published: December 2023

The synthesis and biological evaluation of brassinosteroids (BRs) analogs with chemical modification in the side alkyl chain is a matter of current interest. Recently, a series of BR analogs with phenyl or benzoate groups in the alkyl chain have been reported. The effect of substitution in the aromatic ring on the biological activities of these new analogs has been evaluated, and the results suggest that the bioactivity is enhanced by substitution with an F atom. In this context, we have synthesized, characterized, and evaluated a series of new analogs of 23,24-bisnorcholenic type in which the benzoate group at the C-22 position is substituted with an F atom at “ortho or para” positions. Plant growth-promoting activities were evaluated by using the rice lamina inclination test and bean second internode biotest. The results obtained with both bioassays indicate that the compound with an F atom in the para position on the aromatic ring is the most active BR analog and in some cases is even more active than brassinolide. The docking study confirmed that compounds with an F atom adopt an orientation similar to that predicted for brassinolide, and the F atom in the “para” position generates an extra hydrogen bond in the predicted binding position.
Perturbation of Copper Homeostasis Sensitizes Cancer Cells to Elevated Temperature
Authors: Scutigliani Enzo M. , van Hattum Jons , Lobo-Cerna Fernando , Kruyswijk Joanne , Myrcha Maja , Dekkers Frederique E. G. A. , Hoebe Ron A. , Edwards Finn , Oppelaar Jetta J. , Vogt Liffert , Bootsma Sanne , Bijlsma Maarten F. , Picavet Daisy I. , Crezee Johannes , Oddens Jorg R. , de Reijke Theo M. , Krawczyk Przemek M.
Published: December 2023

Temporary elevation of tumor temperature, also known as hyperthermia, is a safe and well-tolerated treatment modality. The efficacy of hyperthermia can be improved by efficient thermosensitizers, and various candidate drugs, including inhibitors of the heat stress response, have been explored in vitro and in animal models, but clinically relevant thermosensitizers are lacking. Here, we employ unbiased in silico approaches to uncover new mechanisms and compounds that could be leveraged to increase the thermosensitivity of cancer cells. We then focus on elesclomol, a well-performing compound, which amplifies cell killing by hyperthermia by 5- to 20-fold in cell lines and outperforms clinically applied chemotherapy when combined with hyperthermia in vitro. Surprisingly, our findings suggest that the thermosensitizing effects of elesclomol are independent of its previously reported modes of action but depend on copper shuttling. Importantly, we show that, like elesclomol, multiple other copper shuttlers can thermosensitize, suggesting that disturbing copper homeostasis could be a general strategy for improving the efficacy of hyperthermia.
The Anti-Diabetic Potential of Baicalin: Evidence from Rodent Studies
Authors: Szkudelski Tomasz , Szkudelska Katarzyna
Published: December 2023

Baicalin is a biologically active flavonoid compound that benefits the organism in various pathological conditions. Rodent studies have shown that this compound effectively alleviates diabetes-related disturbances in models of type 1 and type 2 diabetes. Baicalin supplementation limited hyperglycemia and improved insulin sensitivity. The anti-diabetic effects of baicalin covered the main insulin-sensitive tissues, i.e., the skeletal muscle, the adipose tissue, and the liver. In the muscle tissue, baicalin limited lipid accumulation and improved glucose transport. Baicalin therapy was associated with diminished adipose tissue content and increased mitochondrial biogenesis. Hepatic lipid accumulation and glucose output were also decreased as a result of baicalin supplementation. The molecular mechanism of the anti-diabetic action of this compound is pleiotropic and is associated with changes in the expression/action of pivotal enzymes and signaling molecules. Baicalin positively affected, among others, the tissue insulin receptor, glucose transporter, AMP-activated protein kinase, protein kinase B, carnitine palmitoyltransferase, acetyl-CoA carboxylase, and fatty acid synthase. Moreover, this compound ameliorated diabetes-related oxidative and inflammatory stress and reduced epigenetic modifications. Importantly, baicalin supplementation at the effective doses did not induce any side effects. Results of rodent studies imply that baicalin may be tested as an anti-diabetic agent in humans.