bluuebunny/crossref_metadata_2025 huggingface dataset:
Controllable orbital-to-spin angular momentum conversion in tight focusing of spatiotemporal vortex wavepacket
Authors: Li Hehe , Shi Xishang , Chen Ruixiang , Hu Huajie , Li Xinzhong
Published: August 2024

In this paper, we investigate the tight focusing of the radially polarized spatiotemporal vortex (STV) wavepackets. We find that, by changing the initial phase of the incident polarization state, the intensity envelope of the tightly focused first-order radially polarized STV wavepacket can be well controlled, yet the intensity envelope just rotates in whole for the tightly focused high-order radially polarized STV wavepacket. Furthermore, we show that, when the initial phase of incident polarization state takes π/2, the transverse double vortex structure arises in the focal region. More interestingly, when the initial phase takes π/2, the pure longitudinal spin angular momentum and transverse orbital angular momentum can be obtained in the tight focusing of the first-order radially polarized STV wavepacket. These effects are the manifestation of the spin-orbit interaction determined by the transverse orbital angular momentum and the incident polarization state. Our works present a technique to modulate the optical angular momentum in the tight focusing of the radially polarized STOV wavepacket, have potential application in the fields of optical switches, optical capture, quantum communication and nano-manipulation.
Comparison of professional and everyday wearable technology at different body positions in terms of recording gait perturbations
Authors: Feld Lea , Schell-Majoor Lena , Hellmers Sandra , Koschate Jessica , Hein Andreas , Zieschang Tania , Kollmeier Birger
Published: August 2024

Falls are a significant health problem in older people, so preventing them is essential. Since falls are often a consequence of improper reaction to gait disturbances, such as slips and trips, their detection is gaining attention in research. However there are no studies to date that investigated perturbation detection, using everyday wearable devices like hearing aids or smartphones at different body positions. Sixty-six study participants were perturbed on a split-belt treadmill while recording data with hearing aids, smartphones, and professional inertial measurement units (IMUs) at various positions (left/right ear, jacket pocket, shoulder bag, pants pocket, left/right foot, left/right wrist, lumbar, sternum). The data were visually inspected and median maximum cross-correlations were calculated for whole trials and different perturbation conditions. The results show that the hearing aids and IMUs perform equally in measuring acceleration data (correlation coefficient of 0.93 for the left hearing aid and 0.99 for the right hearing aid), which emphasizes the potential of utilizing sensors in hearing aids for head acceleration measurements. Additionally, the data implicate that measurement with a single hearing aid is sufficient and a second hearing aid provides no added value. Furthermore, the acceleration patterns were similar for the ear position, the jacket pocket position, and the lumbar (correlation coefficient of about 0.8) or sternal position (correlation coefficient of about 0.9). The correlations were found to be more or less independent of the type of perturbation. Data obtained from everyday wearable devices appears to represent the movements of the human body during perturbations similar to that of professional devices. The results suggest that IMUs in hearing aids and smartphones, placed at the trunk, could be well suited for an automatic detection of gait perturbations.
Moonlighting on the Fasciola hepatica tegument: Enolase, a glycolytic enzyme, interacts with the extracellular matrix and fibrinolytic system of the host
Authors: O’Kelly Eve , Cwiklinski Krystyna , De Marco Verissimo Carolina , Calvani Nichola Eliza Davies , López Corrales Jesús , Jewhurst Heather , Flaus Andrew , Lalor Richard , Serrat Judit , Dalton John P. , González-Miguel Javier
Published: August 2024

Enolase is a 47 kDa enzyme that functions within the glycolysis and gluconeogenesis pathways involved in the reversible conversion of D-2-phosphoglycerate (2PGA) to phosphoenolpyruvate (PEP). However, in the context of host-pathogen interactions, enolase from different species of parasites, fungi and bacteria have been shown to contribute to adhesion processes by binding to proteins of the host extracellular matrix (ECM), such as fibronectin (FN) or laminin (LM). In addition, enolase is a plasminogen (PLG)-binding protein and induces its activation to plasmin, the main protease of the host fibrinolytic system. These secondary ‘moonlighting’ functions of enolase are suggested to facilitate pathogen migration through host tissues. This study aims to uncover the moonlighting role of enolase from the parasite Fasciola hepatica, shedding light on its relevance to host-parasite interactions in fasciolosis, a global zoonotic disease of increasing concern. A purified recombinant form of F. hepatica enolase (rFhENO), functioning as an active homodimeric glycolytic enzyme of ~94 kDa, was successfully obtained, fulfilling its canonical role. Immunoblotting studies on adult worm extracts showed that the enzyme is present in the tegument and the excretory/secretory products of the parasite, which supports its key role at the host-parasite interface. Confocal immunolocalisation studies of the protein in newly excysted juveniles and adult worms also localised its expression within the parasite tegument. Finally, we showed by ELISA that rFhENO can act as a parasitic adhesin by binding host LM, but not FN. rFhENO also binds PLG and enhances its conversion to plasmin in the presence of the tissue-type and urokinase-type PLG activators (t-PA and u-PA). This moonlighting adhesion-like function of the glycolytic protein enolase could contribute to the mechanisms by which F. hepatica efficiently invades and migrates within its host and encourages further research efforts that are designed to impede this function by vaccination or drug design.
The global population stru cture of Lacticaseibacillus rhamnosus and its application to an investigation of a rare case of infective endocarditis
Authors: Santoiemma Phillip P. , Cohn Susan E. , Gatesy Samuel W. M. , Hauser Alan R. , Agrawal Saaket , Theodorou Maria E. , Bachta Kelly E. R. , Ozer Egon A.
Published: August 2024

Background

Lacticaseibacillus (formerly Lactobacillus) rhamnosus is widely used in probiotics or food supplements to promote microbiome health and may also be part of the normal microbiota of the human gastrointestinal tract. However, it rarely also causes invasive or severe infections in patients. It has been postulated that these infections may originate from probiotics or from endogenous commensal reservoirs. In this report, we examine the population structure of Lacticaseibacillus rhamnosus and investigate the utility of using bacterial genomics to identify the source of invasive Lacticaseibacillus infections.

Methods

Core genome phylogenetic analysis was performed on 602 L. rhamnosus genome sequences from the National Center for Biotechnology public database. This information was then used along with newly generated sequences of L. rhamnosus isolates from yogurt to investigate a fatal case of L. rhamnosus endocarditis.

Results

Phylogenetic analysis demonstrated substantial genetic overlap of L. rhamnosus isolates cultured from food, probiotics, infected patients, and colonized individuals. This was applied to a patient who had both consumed yogurt and developed L. rhamnosus endocarditis to attempt to identify the source of his infection. The sequence of the isolate from the patient’s bloodstream differed at only one nucleotide position from one of the yogurt isolates. Both isolates belonged to a clade, identified here as clade YC, composed of mostly gastrointestinal isolates from healthy individuals, some of which also differed by only a single nucleotide change from the patient’s isolate.

Conclusions

As illustrated by this case, whole genome sequencing may be insufficient to reliably determine the source of invasive infections caused by L. rhamnosus.
Early and late adverse clinical outcomes of severe carbon monoxide intoxication: A cross-sectional retrospective study
Authors: Vural Abdussamed , Dolanbay Turgut
Published: August 2024

Background

Carbon monoxide (CO) results from incomplete combustion of carbon-based materials, causing symptoms such as headaches, dizziness, nausea, chest pain, confusion, and, in severe cases, unconsciousness. Normobaric oxygen therapy (NBOT) is the standard therapy, whereas hyperbaric oxygen therapy (HBOT) is recommended in severe cases of organ damage. This study examined the early and late adverse outcomes in patients with severe CO poisoning.

Materials and methods

This study analyzed severe cases of CO poisoning among patients admitted to the emergency department between January 2020 and May 2022. The demographic, clinical, and laboratory data of symptomatic individuals and those requiring HBOT were examined. The study recorded early outcomes, such as intubation and in-hospital mortality, and late outcomes, such as delayed neurological sequelae and 1-year mortality. Chi-square tests, Spearman’s rho correlation tests, and logistic regression analyses were performed to identify factors affecting these outcomes.

Results

Patients who received HBOT showed a significant difference in delayed neurological sequelae (DNS) compared to those who received NBOT (p = 0.037). Significant differences were observed in the need for intubation, in-hospital mortality, and 1-year mortality between patients based on COHb levels, but no significant differences were found in DNS. The 1-year mortality probability was significantly influenced by COHb level (odds ratio = 1.159, 95% CI [1.056–1.273]). Patients receiving NBOT had a higher odds ratio for DNS risk than those receiving HBOT (odds ratio = 8.464, 95% [1.755–40.817], p = 0.008).

Conclusion

The study showed no differences in intubation, in-hospital mortality, and 1-year mortality rates between the HBOT and NBOT groups. However, significant differences in DNS suggest that treatment modalities have different effects on neurological outcomes. High COHb levels are associated with an increased risk of intubation, and mortality underscores the significance of monitoring COHb levels in clinical evaluations.
The effects of light emitting diodes on mitochondrial function and cellular viability of M-1 cell and mouse CD1 brain cortex neurons
Authors: Lee Jong Soo , Park Hyun Jin , Kang Sang Ook , Lee Sang Hak , Lee Chang Kyu
Published: August 2024

The invention of Light Emitting Diode (LED) revolutionized energy-efficient illumination, but concerns persist regarding the potential harm of blue light to our eyes. In this study, we scrutinized the impact of LED light characteristics on eyes using two cell types: M-1 (rich in mitochondria) and CD-1 (neuronal). Variations in color rendering index (CRI) and correlated color temperature (CCT) were investigated, alongside exposure durations ranging from 0 to 24 hours. The findings illuminated the potential benefits of high-quality LED lighting, characterized by a high CRI and low CCT, which emits a greater proportion of red light. This form of lighting was associated with enhanced cell proliferation, elevated ATP levels, and reduced oxidative stress. In contrast, LEDs with low CRI and high CCT exhibited adverse effects, diminishing cell viability and increasing oxidative stress. These results suggest that high-quality LED lighting may have neuroprotective potential as a treatment option, such as for retinal ganglion cells.
Improving pediatric procedural skills and EPA assessments through an acute care procedural skills curriculum
Authors: Mirza Maaz , Bilgic Elif , Gupta Ronish , Ngo Quang N. , Forward Karen
Published: August 2024

Introduction

Acute procedural skill competence is expected by the end of pediatric residency training; however, the extent to which residents are actually competent is not clear. Therefore, a cross-sectional observational study was performed to examine the competency of pediatric residents in acute care procedures in emergency medicine.

Materials and methods

Pediatric residents underwent didactic/hands-on “Acute Procedure Day” where they performed procedures with direct supervision and received entrustable professional activity (EPA) assessments (scores from 1–5) for each attempt. Procedures included: bag-valve mask (BVM) ventilation, intubation, intraosseous (IO) line insertion, chest tube insertion, and cardiopulmonary resuscitation (CPR) with defibrillation. Demographic information, perceived comfort level, and EPA data were collected. Descriptive statistics and Pearson correlation for postgraduate year (PGY) versus EPA scores were performed.

Results

Thirty-six residents participated (24 PGY 1–2, and 12 PGY 3–4). Self-reported prior clinical exposure was lowest for chest tube placement (n = 3, 8.3%), followed by IOs (n = 19, 52.8%). During the sessions, residents showed the highest levels of first attempt proficiency with IO placement (EPA 4–5 in 28 residents/33 who participated) and BVM (EPA 4–5 in 27/33), and the lowest for chest tube placement (EPA 4–5 in 0/35), defibrillation (EPA 4–5 in 5/31 residents) and intubation (EPA 4–5 in 17/31). There was a strong correlation between PGY level and EPA score for intubation, but not for other skills.

Discussion

Entrustability in acute care skills is not achieved with current pediatrics training. Research is needed to explore learning curves for skill acquisition and their relative importance.
Financial toxicity and acute injury in the Kilimanjaro region: An application of the Three Delays Model
Authors: Frankiewicz Parker , Sawe Yvonne , Sakita Francis , Mmbaga Blandina T. , Staton Catherine , Joiner Anjni P. , Smith Emily R.
Published: August 2024

Background

Trauma and injury present a significant global burden–one that is exacerbated in low- and middle-income settings like Tanzania. Our study aimed to describe the landscape of acute injury care and financial toxicity in the Kilimanjaro region by leveraging the Three Delays Model.

Methods

This cross-sectional study used an ongoing injury registry and financial questionnaires collected at Kilimanjaro Christian Medical Centre (KCMC) in Moshi, Tanzania from December 2022 until March 2023. Financial toxicity measures included catastrophic expenditure and impoverishment, in accordance with World Health Organization standards. Descriptive analysis was also performed.

Findings

Most acute injury patients that presented to the KCMC Emergency Department experienced financial toxicity due to their out-of-pocket (OOP) hospital expenses (catastrophic health expenditure, CHE: 62.8%; impoverishment, IMP: 85.9%). Households within our same which experienced financial toxicity had more dependents (CHE: 18.4%; IMP: 17.9% with ≥6 dependents) and lower median monthly adult-equivalent incomes (CHE: 2.53 times smaller than non-CHE; IMP: 4.27 times smaller than non-IMP). Individuals experiencing financial toxicity also underwent more facility transfers with a higher surgical burden.

Interpretation

Delay 1 (decision to seek care) and Delay 2 (reaching appropriate care facility) could be significant factors for those who will experience financial toxicity. In the Tanzanian healthcare system where national health insurance is present, systematic expansions are indicated to target those who are at higher risk for financial toxicity including those who live in rural areas, experience unemployment, and have many dependents.
Computational thinking in university students: The role of fluid intelligence and visuospatial ability
Authors: Aranyi Gabor , Kovacs Kristof , Kemény Ferenc , Pachner Orsolya , Klein Balázs , Remete Eszter P.
Published: August 2024

Computational thinking (CT) is a set of problem-solving skills with high relevance in education and work contexts. The present paper explores the role of key cognitive factors underlying CT performance in non-programming university students. We collected data from 97 non-programming adults in higher education in a supervised setting. Fluid intelligence, crystallized intelligence, and visuospatial ability were assessed using computerized adaptive tests; CT was measured using the Computational Thinking test. The direct and indirect effects of gender and visuospatial ability through fluid intelligence on CT were tested in a serial multiple mediator model. Fluid intelligence predicted CT when controlling for the effects of gender, age, and visuospatial ability, while crystallized intelligence did not predict CT. Men had a small advantage in CT performance when holding the effects of cognitive abilities constant. Despite its large correlation with gender and CT, visuospatial ability did not directly influence CT performance. Overall, we found that programming-naive computational thinkers draw on their reasoning ability that does not rely on previously acquired knowledge to solve CT problems. Visuospatial ability and CT were spuriously associated. Drawing on the process overlap theory we propose that tests of fluid intelligence and CT sample an overlapping set of underlying visuospatial processes.
Analysis of the impact of RCEP on the industrial and innovation chains of China’s textile and clothing industry
Authors: Yang Li , Kumarasinghe Pivithuru
Published: August 2024

This research examines the impact of the Regional Comprehensive Economic Partnership (RCEP) on the textile and apparel industry within its member nations. The study seeks to understand the implications of RCEP on trade dynamics, innovation chains, and industrial integration in the textile sector. The study uses both quantitative analysis of trade data and qualitative assessment of policy frameworks to analyze changes in textile trade and patterns among RCEP members through UN Comtrade data. Qualitative analysis is conducted to examine RCEP policies related to intellectual property protection, investment regulations, and innovation cooperation. The findings reveal a significant increase in textile trade volume among RCEP member countries following the agreement’s implementation. China emerges as a key player, experiencing substantial growth in textile exports to RCEP nations, particularly driven by tariff reduction initiatives. RCEP provisions stimulate demand for innovation within the textile industry, fostering collaborative efforts in scientific research and development.
RVFV virulence factor NSs triggers the mitochondrial MCL-1-BAK axis to activate pathogenic NLRP3 pyroptosis
Authors: Guan Zhenqiong , Li Huiling , Zhang Chongtao , Huang Ziyan , Ye Meidi , Zhang Yulan , Li Shufen , Peng Ke
Published: August 2024

Infection of Rift Valley fever virus (RVFV), a highly pathogenic mosquito-borne zoonotic virus, triggers severe inflammatory pathogenesis but the underlying mechanism of inflammation activation is currently unclear. Here, we report that the non-structural protein NSs of RVFV triggers mitochondrial damage to activate the NLRP3 inflammasome leading to viral pathogenesis in vivo. It is found that the host transcription inhibition effect of NSs causes rapid down-regulation of myeloid cell leukemia-1(MCL-1), a pro-survival member of the Bcl-2 (B-cell lymphoma protein 2) protein family. MCL-1 down-regulation led to BAK activation in the mitochondria, which triggered mtROS production and release of oxidized mitochondrial DNA (ox-mtDNA) into the cytosol. Cytosolic ox-mtDNA binds and activates the NLRP3 inflammasome triggering NLRP3-GSDMD pyroptosis in RVFV infected cells. A NSs mutant virus (RVFV-NSsRM) that is compromised in inducing transcription inhibition did not trigger MCL-1 down-regulation nor NLRP3-GSDMD pyroptosis. RVFV infection of the Nlrp3-/- mouse model demonstrated that the RVFV-triggered NLRP3 pyroptosis contributed to RVFV inflammatory pathogenesis and fatal infection in vivo. Infection with the RVFV-NSsRM mutant virus similarly showed alleviated inflammatory pathogenesis and reduced fatality rate. Taken together, these results revealed a mechanism by which a virulence factor activates the mitochondrial MCL-1-BAK axis through inducing host transcription inhibition to trigger NLRP3-dependent inflammatory pathogenesis.
Rab27a GTPase and its effector Myosin Va are host factors required for efficient Oropouche virus cell egress
Authors: Concha Juan O. , Gutierrez Kristel , Barbosa Natalia , Rodrigues Roger L. , de Carvalho Andreia N. , Tavares Lucas A. , Rudd Jared S. , Costa Cristina S. , Andrade Barbara Y. G. , Espreafico Enilza M. , Crump Colin M. , daSilva Luis L. P.
Published: August 2024

Oropouche fever, a debilitating illness common in South America, is caused by Oropouche virus (OROV), an arbovirus. OROV belongs to the Peribunyaviridae family, a large group of RNA viruses. Little is known about the biology of Peribunyaviridae in host cells, especially assembly and egress processes. Our research reveals that the small GTPase Rab27a mediates intracellular transport of OROV induced compartments and viral release from infected cells. We show that Rab27a interacts with OROV glycoproteins and colocalizes with OROV during late phases of the infection cycle. Moreover, Rab27a activity is required for OROV trafficking to the cell periphery and efficient release of infectious particles. Consistently, depleting Rab27a’s downstream effector, Myosin Va, or inhibiting actin polymerization also hinders OROV compartments targeting to the cell periphery and infectious viral particle egress. These data indicate that OROV hijacks Rab27a activity for intracellular transport and cell externalization. Understanding these crucial mechanisms of OROV’s replication cycle may offer potential targets for therapeutic interventions and aid in controlling the spread of Oropouche fever.
Juan Muñoz, In the Violet Hour
Authors: Grenier Béatrice
Published: August 2024

Review of: Juan Muñoz, In the Violet Hour

Curated by Manuel Segade, Centro Dos Mayos, 17 June 2023–7 January 2024 and Sala Alcala 31, 14 February 2023–9 July 2023, Madrid
Molecular Structure, Spectroscopy, Molecular Docking and ADMET Studies of 2,5-Dimethylbenzaldehyde Semicarbazone as Potent Breast Cancer Agent
Authors: Sumathi S. , Jeyavijayan S. , Karthik N. , Karthikeyan A. , Murugan Palani , Kunjumol V.S.
Published: August 2024

The vibrational wavenumbers of 2,5-dimethylbenzaldehyde semicarbazone (DBS) were compared using the DFT-B3LYP/6-311++G(d,p) method after the FTIR and FT-Raman spectra were measured in the ranges of 4000-400 cm-1 and 4000-0 cm-1, respectively. The computed and experimental XRD results were compared with the optimized geometries. The energy gap between the lowest unoccupied molecular orbital (LUMO) and the highest occupied molecular orbital (HOMO) as well as the molecule electrostatic potentials (MEP) has been illustrated using charge density distributions indicative of the biological response. The absorption spectra were generated using time-dependent density functional theory calculations on the same basis set. An investigation of natural bonds has revealed strong electron delocalization whereas the electrical properties of the molecule have been elucidated using the Fukui function and Mulliken charge analysis. Molecular orbital contributions were investigated using densities of states (DOS) spectrum. The docking investigation, which was conducted against the protein 1AQU associated with breast cancer revealed that the largest binding energy was -8.3 kcal/mol. To assess the drug-likeness of the compound, an ADMET analysis has also been conducted and examined. Novel insights on the molecular structure will become possible as a result of these theoretical findings.
Controles de proteção de dados pessoais dos povos indígenas implementados na FUNAI:
Authors: Prestes Felipe Pinheiro , Ribeiro Preve Daniel , Teza de Bona Marcio
Published: August 2024

O foco desta pesquisa está na proteção dos dados pessoais tratados pela Fundação Nacional dos Povos Indígenas (FUNAI) sob a ótica do Acórdão n. 1.384/2022 do Tribunal de Contas da União (TCU), referente à auditoria realizada na organização, a fim de obter dados de sua adequação à Lei Geral de Proteção de Dados (LGPD). Portanto, a problemática de pesquisa é justamente saber se a FUNAI está satisfatoriamente adequada à LGPD por meio dos resultados da auditoria. Nesse sentido, em um primeiro momento, buscou-se demonstrar a evolução e adequação da tutela da privacidade dos dados pessoais em um contexto histórico se perfectibilizando em um direito fundamental referente ao tema. Em seguida, foram tratados conceitos legais da LGPD aplicáveis ao estudo, bem como feita a caracterização dos dados pessoais do indígena. Por fim, deu-se especificamente a análise do referido acórdão do TCU, sendo apontadas algumas críticas necessárias, dada a sensibilidade do tema estudado. Neste trabalho, foi adotada a metodologia exploratória e descritiva documental, em conjunto com o método hipotético-dedutivo. Como resultado, evidencia-se o descompasso da FUNAI à LGPD, bem como a evidente possibilidade de riscos de grande monta à população indígena em caso de incidentes de segurança da informação, mas há possibilidade de melhoria nas lacunas encontradas na pesquisa, na FUNAI.
Fundamentos pedagógico-educacionais renovadores e tecnicistas e teorias técnicas do currículo: determinações históricas e implicações para o pensamento educacional brasileiro
Authors: Maia Júlio César , Silveira Carla Carolina Rodrigues da , Sacardo Michele Silva
Published: August 2024

O artigo objetiva resgatar o movimento de ascensão das teorias pedagógicas, educacionais e curriculares renovadoras e tecnicistas. Fragmenta-se, inicialmente, em quatro seções, respectivamente orientadas à apresentação: i) da resposta encontrada pelos fundamentos pedagógicos-educacionais renovadores ao tradicionalismo; ii) do progressivismo de J. Dewey enquanto primeira ofensiva das teorias técnicas do currículo; iii) do tecnicismo de F. Bobbitt enquanto segunda ofensiva e; iv) da síntese técnico-linear de R. Tyler enquanto terceira e última ofensiva desse conjunto de teorias. Objetiva, em seguida, apreender ainda a chegada dessas teorias ao Brasil. Para tanto, duas outras seções são evidenciadas, orientadas respectivamente à apresentação: i) do contributo dos pioneiros da educação para a crítica dos fundamentos pedagógico-educacionais tradicionais e difusão das teorias técnicas do currículo nesse país e; ii) dos obstáculos assumidos pela ênfase progressivista renovadora a partir da fixação das ideias técnico-lineares do currículo sobre o componente educacional brasileiro.
Educación común universal y obligatoria en los Territorios Nacionales. Un mandato sin recursos suficientes (Argentina, 1884-1900)
Authors: Barro Cecilia del
Published: August 2024

La creación de escuelas y la edificación en los Territorios Nacionales, como en otras jurisdicciones, fue una de las principales demandas a las que debió responder el Consejo Nacional de Educación (CNE) a finales del siglo XIX, en tanto que para exigir la obligatoriedad escolar debe garantizarse el acceso a las mismas. Tratándose de vastas regiones, con poblaciones dispersas y con una composición social heterogénea, el requisito poblacional dictaminado por la Ley Nº 1420 supuso una franca contradicción con el contexto de aplicación en las gobernaciones. Sin embargo, la escuela debía crearse por doquier, pero el mandato no se correspondía con los recursos asignados que, sin ser pocos, eran insuficientes. En este trabajo nos proponemos reconstruir los diagnósticos y la institucionalización que fueron dando nitidez a las políticas estatales vinculadas a la escolarización de la educación común universal y obligatoria en los Territorios Nacionales (1884-1900). A tal fin empleamos en forma combinada metodologías cualitativas y cuantitativas que nos permiten realizar análisis en diferentes escalas: microhistórico para comprender la dinámica del CNE y las experiencias locales, y más global para describir las políticas educativas y sus relaciones con los actores sociales.
PENGEMBANGAN APLIKASI KLIK ME! SEBAGAI MEDIA LAYANAN KONSELING RAMAH DISABILITAS DI ERA SOCIETY 5.0
Authors: Sari Fera Puspito
Published: August 2024

Along with digital transformation in the era of society 5.0, counseling services can be carried out indirectly through the internet network and using a communication medium called cyber counseling. The development of digital counseling service applications is expected to be the right innovation to create inclusive e-counseling services. This study uses the Research and Development (RnD) method with the ADDIE model (Analysis, Design, Development, Implementation and Evaluation). But, this research conducted only reached the development stage. Data collection techniques using observation, interviews, and questionnaires. The results of this study indicate that the Klik Me! Application the counselee contains dashboard menus, assessment lists, consultation schedules, live chat and announcements. The results of the feasibility assessment of media experts were 86.7%, material experts 92.5%, non-disabled counselees 83% and 89% disabled counselees, this shows that the application Klik Me! very worthy to use. Click Me App! It is also considered as disability-friendly media that is accessible for blind and deaf people.
 
Keywords: disability friendly, Klik Me! application, media counseling
Can liberal democracies thrive with consumption limits? Barriers to implementing consumption corridors
Authors: Kalke Karoline , Haderer Margaret , Hausknost Daniel , Deflorian Michael
Published: August 2024

Consumption limits and sufficiency approaches face growing opposition in today’s political landscape. While proponents of consumption corridors (CCs) assume that setting upper consumption limits is achievable in liberal democracies, we argue that the tensions between CCs and liberal
democracy are more profound than suggested. We examine the role of (high) consumption in liberal democracies to better understand the barriers to achieving a good life for all within planetary boundaries.In sustainability debates, the concept of consumption corridors (CCs) has gained prominence.
CCs are understood to achieve a good life for all within planetary boundaries. This concept operates on the premise that setting upper limits to consumption is in principle feasible within liberal democracies. But to what extent, if at all, are upper limits to consumption compatible with liberal
democracy? In this article, we argue that the tensions between CCs and liberal democracy may run deeper than proponents of CCs suggest. Because consumption plays a constitutive role in social reconciliation, the formation and exercise of autonomy, and democratic legitimacy in liberal democracies,
introducing upper limits may indeed hit harder boundaries ‐ boundaries that sufficiency approaches to reducing consumption (and production) levels increasingly face in the current political landscape. Sharing the normative horizon of a good life for all, we propose that for CCs to become
a viable lever for transformative change, a deeper analysis of existing barriers may be in order.
,,So wird Humanökologie lebendig!“
Authors: Harrer-Puchner Gabriele , Gaugler Tobias
Published: August 2024

Seit Mai 2024 hat die Deutsche Gesellschaft für Humanökologie erstmalig eine Präsidentin. Anhand von drei Fragen geben wir ihr und einem jüngeren Vorstandsmitglied Gelegenheit, sich selbst und ihre Forschungsprojekte vorzustellen, denn besser kann man kaum erklären,
was Humanökologie heute bedeutet.
The Formation of Ethnically Distinct Villages in Jember during the Colonial Period (1870-1942)
Authors: Widuatie Ratna Endang , Winarni Retno
Published: August 2024

The development of the plantation economy in Jember at the end of the 19th century required a large workforce, something that could not be met by the local population. The colonial government responded by bringing in workers from western East Java, the Vorstenlanden, and Madura Island. These migrants eventually settled in Jember and became pioneers for subsequent waves of migration until the Second World War. The entry of Javanese and Madurese people into Jember shaped the physical characteristics of settlements that have survived to this day. The settlement arrangements made by the colonial government were based on ecological and cultural considerations of migrants, and plantation-oriented resulted in a unique pattern of segregation. After Indonesia's independence, villages in Jember became more fluid in terms of demographic composition, however, the physical and cultural characteristics that indicate a village has Javanese or Madurese cultural roots are still clearly visible. This article describes the process of the formation of villages in Jember with a comparison of “Javanese villages” and “Madurese villages” to find out how far the colonial government's intervention influenced the formation of villages, and how the villagers concerned maintain their cultural identity as migrant newcomers.
Road Infrastructure Development in Jambi Province During the New Order Period
Authors: Musdalifah Musdalifah , Hartatik Endah Sri , Rinardi Haryono
Published: August 2024

This article examines the development of road infrastructure in Jambi Province during the New Order era and its impact on the socioeconomic aspects of the local community. The study employs a historical research methodology, encompassing heuristics, source criticism, interpretation, and historiography. The development initiatives of the New Order period were pivotal in the expansion of road infrastructure in Jambi Province. This infrastructure development, particularly road construction, was integrated into the Five-Year Development Plans (Repelita) and implemented in phases. For Jambi Province, the Repelita aimed to accelerate development and bridge the gap with other regions. This study analyzes the impact of infrastructure development, specifically focusing on its role in facilitating economic activity and the mobility of people and goods. The findings reveal that infrastructure development contributed significantly to social and economic life, including increased agricultural yields, diversification of professions, the emergence of new productive areas, changes in demographics and multi-ethnic diversity, and an overall improvement in the quality of life for the population.
Inya: Wet Nurse and Succesful Regeneration of the Mataram Islamic Court Authorities in the Past
Authors: Sumarno Sumarno , Fibiona Indra , Lestari Siska Nurazizah
Published: August 2024

The fame of Islamic Mataram, a kingdom that encompassed Java and its surroundings, is reflected in its strong Javanese culture. Since the Mataram era, Javanese culture has been an important part of Javanese life. One of the main characteristics of the culture that is inherent in the lives of Javanese people is Inya. Inya is the term for the nurse or mother of the king's baby who is considered a symbol of the fame of the Islamic Mataram kingdom. This study discusses the ins and outs of Inya and its contribution to the regeneration of the rulers of the Islamic Mataram palace. The method used in this study is the Historical method. Data search focused on literature studies related to the empowerment of Inya in the past. The results of this study indicate that Inya has a very important role in the regeneration of the rulers of the Islamic Mataram palace. Inya has the task of raising and caring for the king's baby. Inya also has an obligation to educate and train the king's baby according to the procedures and customs of the Islamic Mataram community.
Social and Cultural Integration: A Discourse Analysis of Islamic Themes in the Basis Magazine, 1998–2000
Authors: Yuliantri Rhoma Dwi Aria
Published: August 2024

This article examines the discourse on Islam found in articles published in Basis from 1998 to 2000. Basis is a cultural magazine founded in Yogyakarta by members of the Society of Jesus (SJ) in 1951. Since 1998, Basis has regularly featured writings on Islamic themes contributed by both Muslim and non-Muslim intellectuals. This research aims to understand why Basis, with its Catholic missionary vision and spirit, embraced Islamic themes during the 1998–2000 period and to what extent these Islamic and Islamic-themed articles reflect the journal's mission of interreligious dialogue in response to the "cultural freedom" of the Reform Era. A historical methodology using text analysis techniques was employed for this research. Primary sources included articles with Islamic themes published in Basis between 1998 and the early 2000s, as well as interview data. The findings indicate that following the fall of the New Order regime in 1998, Indonesia experienced "cultural freedom," including increased freedom of expression, which significantly influenced the media landscape. Basis' inclusion of articles with Islamic themes was a response to this "cultural freedom" in the contemporary context. The Islamic discourse presented in Basis primarily focused on contextual issues related to religious polarization and conflicts in Indonesia at the dawn of the Reform Era, including discussions on pluralism and the significance of interreligious dialogue within the framework of the nation-state. The Islamic discourse in Basis demonstrated a fluid nature, suggesting coexistence and close interaction among adherents of various value systems and worldviews.
Green Competitive Advantage dan Faktor Fraud dalam Mempengaruhi Kecurangan Laporan Keuangan
Authors: Megawati Rosim , Murwaningsari Etty
Published: August 2024

This study aims to determine the effect of green competitive advantage factors and fraud: frequency of number of CEO photos, unstable organizational structure, financial target, ineffective monitoring, and political connection to fraudulent financial statement. This observation uses secondary annual reporting and sustainability data from all corporate sectors except the banking sector, with a total of 220 from 2020 to 2021, listed on idx.co.id and the company's official website Determination of the sample in this test is done with a targeted sampling procedure to get a representative sample in accordance with the criteria of the researcher. Logistics regression analysis is an analytical tool in this study using SPSS version 22 program. The result of this study are green competitive advantage, unstable organizational structure, ineffective monitoring, and political connections have a negative impact. While the number of CEO photos and financial targets have a significant positive effect on fraud.
Pengaruh Kompetisi dan Kerjasama Terhadap Kinerja Individu dengan Iklim Kepedulian Sebagai Variabel Mediasi Serta Informasi Kinerja Relatif Sebagai Variabel Moderasi
Authors: Hartono Yudi , Murniati Monika Palupi
Published: August 2024

This study aims to measure the effect of cooperation and competition on individual performance through a caring climate as a mediating variable and relative performance information as a moderating variable. The research was carried out with the quantitative methods and data was collected directly using a scale measurement survey to the research partisipants. The results of the regression analysis on this study show the empirical evidence that the cooperation and competition assignments can have a direct effect on performance. Meanwhile the caring climate variable can’t mediate the effect of competition and cooperation model to the individual performance. In the other hand, relative performance information can has a significant influence on the relationship between caring climate and performance.
FENOMENA AUDIT DELAY: FINANCIAL DISTRESS PASCA COVID-19
Authors: Mardjono Enny Susilowati , Astutie Yanti Puji
Published: August 2024

This study aims to examine the impact of financial distress on audit delay pre-COVID-19 period and firm size, profitability and reputation of audit firms as control variables.  The population used in this study are manufacturing companies in the Indonesia Stock Exchange 2018-2020 with a total sample of 189 samples. Sampling is based on a purposive sampling method with certain criteria. Panel data regression analysis is used in the study. The results showed that Audit delay increased in the pre-COVID-19 period than in Post COVID-19 period. The Finacial distress has a significant positive effect on audit delay in the pre-COVID-19 period. Meanwhile, all control variables such as type of audit firms, profitability and reputation of audit firms have negative effects on audit delay pre-COVID-19 period.
DETERMINANTS OF AUDIT QUALITY IN THE PUBLIC SECTOR
Authors: Rahmawaty Rahmawaty , Darwanis Darwanis , Abdullah Syukriy
Published: August 2024

This study aims to provide a literature review on audit quality in the public sector. There are 15 articles used from 3 journal categories, namely Scopus quartile 2, international, and national indexed by Sinta 3 which were published from 2017 to 2021. This study used the Systematic Literature Review method developed by Kitchenham et al (2009). Article searches are carried out through the publish or perish application with a search focus on Scopus as the main search source. Researchers also use search sources from Google Scholar as a secondary source of supporting data. The results showed that there were 6 dominant determination factors used to measure audit quality in the 15 selected articles, namely competence, independence, professional skepticism, professional ethics, motivation, and time budget pressure.
TESTING THE FACTORS THAT CAUSE HERDING BEHAVIOR ON THE INDONESIAN STOCK MARKET
Authors: Talebong Kevin , Pagalung Gagaring , Afdal Afdal
Published: August 2024

This study aims to examine and analyze the effect of stock return, market capitalization, and information asymmetry on herding behavior. The data used are secondary data obtained from the annual report of the company that is the object of research. The population in this study is all companies whose shares are listed in the LQ45 stock index for 2020-2022. Sample selection using purposive sampling and data analysis was carried out by multiple linear regression analysis. The results showed that stock returns had an effect in triggering herding behavior, while market capitalization and information asymmetry had no effect on triggering herding behavior. However, stock return, market capitalization, and information asymmetry together affect herding behavior.
CORPORATE GOVERNANCE AND FINANCIAL TRANSPARENCY: EVIDENCE FROM INDONESIAN MANUFACTURING COMPANIES
Authors: Winoto Surya Adi , Bandi Bandi
Published: August 2024

Corporate scandals enhance shareholders' concerns regarding the company's financial transparency. This study aims to examine the relationship between corporate governance and financial transparency. Multiple regression model is used to test the hypothesis on a sample of manufacturing companies listed on the Indonesian Stock Exchange from 2018 to 2022. The study find that financial transparency increases when frequency of audit committee activity and percentage of institutional ownership increases. However, the study find that independent commissioner has no impact on financial transparency.
ANALISIS SEGMENTASI DAN TARGET PASAR PENDIRIAN RUMAH SAKIT BUNDA MULYA KABUPATEN BOGOR
Authors: Mufakhhir Abdulaziez , Jati Sutopo Patria , Arso Septo Pawelas , Kartasurya Martha Irene , Firman Firman
Published: August 2024

Introduction: The right marketing strategy is not only limited to promoting products, but also arranging segmentation, namely dividing product marketing based on target customers and target markets. Hospitals really need a marketing strategy to face all changes and challenges both internal and external to a company.Purpose: To analyze segmentation and determine the target market for the establishment of Bunda Mulya Hospital in Bogor RegencyMethods: Quantitative and qualitative research approaches (mixed methods). The quantitative approach used in this research is analytical observational with a cross sectional design. The qualitative approach in this research uses a grounded theory type of design. Market segmentation analysis was carried out to determine the appropriate target market for the establishment of Bunda Mulya Hospital through geographic, demographic, psychographic and behavioral approaches. The research subjects were the people of Bogor Regency, the Chair of PERSI Banten Province, Deputy Chair II of PERSI West Java Province, the Bogor Regency Health Service, and the Main Director of the Bunda Mulya Pratama Clinic.Results: The appropriate target market for establishing Bunda Mulya Hospital is the community around Bunda Mulya Hospital (travel time < 30 minutes) with an age range of teenagers - early adults (12-45 years), female, with a predominant high school/equivalent education level. by private workers, families of 2-4 people with total family income between 3-5 million. The public hopes to get fast treatment and complete specialist doctors. The community gets most of the information from neighbors/cadres/friends and visits 1-5x/year. The public provides suggestions regarding class I inpatient rates of <250,000, VIP class inpatient rates of <400,000, general practitioner consultation fees between 40,001-50,000, specialist doctor consultation fees between 100,001-125,000, normal delivery package costs between 1.5-2.5 million and The cost of an ultrasound examination is between 150,000-250,000. Most of the people around Bunda Mulya Hospital are willing to undergo examinations at Bunda Mulya HospitalConclusion: Plans for establishing a new hospital should pay attention to the needs of people of productive age (26-45 years), especially women. The public expects to receive fast service and complete specialist doctors. Therefore, this becomes input for Hospital Management to be able to meet community needs. Hospital financing should pay attention to the UMR limit for Bogor Regency where costs are adjusted for middle and lower middle class people
FAKTOR-FAKTOR YANG MEMPENGARUHI KINERJA KADER POSYANDU TERHADAP PERCEPATAN PENURUNAN STUNTING: Studi di Wilayah Kerja Puskesmas Sungai Durian Kabupaten Kubu Raya, Provinsi Kalimantan Barat
Authors: Ita Margaretha , Kosasih Kosasih , Utoyo Widjajanti
Published: August 2024

Stunting is a condition where a child fails to grow properly during the first 1000 days of life due to long-term malnutrition. This research aim is to identify the factors (Knowledge, Motivation, Training, Attitude) that affect the performance of posyandu cadres in accelerating Stunting reduction within the Sungai Durian Health Center work area, using quantitative research methods with descriptive and verification analysis. The results of the descriptive analysis showed that knowledge had an excellent average score of 4.03, motivation had a good average score of 3.66, training had a good average score of 3.80, and attitudes had a good average score of 3.76. Based on the T count and T table results, knowledge influenced with a score of 6.642 > 2.023, motivation with a score of 4.287 > 2.023, training with a score of 2.598 > 2.023, and attitudes with a score of 3.652 > 2.023. Means there is an influence based on the results of the T test the most influence factor is knowledge on accelerating Stunting reduction. The F test showed that the performance factors of posyandu cadres, which are knowledge, motivation, training, and attitudes, collectively affect the acceleration of Stunting reduction, with an F count score of (752.317 > 2.61). The significance of the F score was 0.000, and the R Square value was 0.893, meaning that 89.3% of the independent variables were bound, while the remaining 10.7% was influenced by other variables that were not included in this research model.