bluuebunny/crossref_metadata_2025 huggingface dataset:
Iono-molecular Separation with Composite Membranes II. Preparation and characterization of polysulphone and composite nanoparticles
Authors: Ani Hussam Nadum Abdalraheem Al , Cimbru Anca Maria , Trisca-Rusu Corneliu , Tanczos Szidonia Katalin , Cuciureanu Adriana , Nechifor Aurelia Cristina
Published: February 2020

This paper illustrates the possibility of producing iono-molecular separations using ionic colloidal ultrafiltration membrane of polysulfone synthetic solutions of cupric ions and nitro phenols through ultrafiltration assisted by polymeric nanoparticle composites based on polysulfone. In the present work, in order to reduce the operating pressure and increase the flow of water we are using the process of ultrafiltration through a polysulfone membrane in N-methylpyrrolidone 10% prepared by coagulation in isopropanol. The nanoparticles needed in colloidal ultrafiltration had been obtained through the immersion technique of precipitation of a solution of 5% PSf in N-methyl pyrrolidone containing 3% aniline in lower alcohols: methanol, ethanol, and isopropanol, followed by the oxidation of the remaining aniline in a solution of 10% hydrochloric acid and ammonium persulfate. The Nanoparticles of polysulfone (NP-PSf) and The three obtained variants of nanoparticles composites (NP-PSf-PANI) were morphologically (SEM) and (AFM), structurally and compositionally (FTIR) characterized and the results show that nanoparticles polysulfone have a much lower range than the composites. The Possibility of copper complexation by both nitrophenols, and by nanoparticle surface probably lead to the formation of more stable aggregates in the supply, which can sufficiently justify the increased retention. The Retentions of the chemical species in question use in all the tests made the same series:R NP-PSf-PANI-M] R NP-PSf-PANI-E] R NP-PSf-PANI-P] R NP-PSf
Electrochemical Characterization of Surface Oxide Films Formed on Silicon Electrodes in 3% Sodium Chloride
Authors: Allaoua Malha Nazef , Bounoughaz Moussa , Lamari Rachid
Published: February 2020

The study focused on the effect of cooling rate on the behaviour of oxide layers formed on silicon (Si) electrodes in 3% Sodium Chloride. All analysis conducted by electrochemical and spectral techniques confirmed that the stability of the silicon oxide film is influenced by the cooling kinetic used in the manufacturing process of Si material. The electronic structure model studied by Mott-Schottky measurements describes the passive film as a hetero-junction (p-n) composed of a metal/Si oxides interface and Si hydroxides/electrolyte interface.
Bisphosphonates in Bone Diseases Treatment
Authors: Lazar Adela Cristina , Pacurar Mariana , Campian Radu Septimiu
Published: February 2020

Bisphosphonates are the most frequently used drugs in the treatment of various bone and cancer diseases. They are complex chemical compounds, having a structure similar to that of pyrophosphates, but with certain differences: i.e., bisphosphonates have P-C-P in their composition; instead of an oxygen atom, a carbon atom is present. The R1 and R2 chains bind to the carbon atom and thus, the antiresorptive capacity of bisphosphonates on the one hand, and their bone-binding capacity on the other hand are stimulated. Through their action, they favor the treatment of diseases for which they have been prescribed, but they can also favor a number of undesired side effects.
Transeterification of the Intermediate Chloro-ester Compounds in the Sequence for Obtaining Corey Aldehyde Protected as Cyclic Acetals
Authors: Tanase Constantin I. , Draghici Constantin , Caproiu Miron Teodor , Cojocaru Ana
Published: February 2020

Transesterification of the TBDMS-bis-protected compounds 10-1a and 10-2a with K2CO3 in methanol takes place with the cleavage of the secondary TBDMS group to compounds 13-1 and 13-2. The same compounds were obtained as proof of the transesterification of the bis-benzoate compounds 10-1b and 10-2b. In case of bis-THP protected compounds 10-1c and 10-2c, the secondary THP group, stable in base conditions, was expected not to be removed in transesterification conditions, resulting the compounds rezultind compusii 13-1c and 13-2c.
The Study of Magnetization in Strong Magnetic Fields for Fe62-XCo10NbXY8B20 (X=0,1,2) Alloys
Authors: Gruszka Konrad , Nabialek Marcin , Szota Michal , Vizureanu Petrica , Abdullah Mohd Mustafa Al Bakri , Bloch Kasia , Sandu Andrei Victor
Published: February 2020

The magnetization process in the area called the approach to ferromagnetic saturation for Fe62-xCo10NbxY8B20 (x = 0, 1, 2) bulk alloys was analyzed. The research were performed using the LakeShore vibrating magnetometer in the fields range of 0 T to 2 T. In the studied alloys, in strong magnetic fields, the structural defects affect magnetization process and the type of these defects was designated � on the basis of the Kronm�ller theory. The article shows that the addition of niobium instead of the iron slightly decreases the saturation magnetization and decreases the value of the coercivity field by filling structure voids leading to material increase in homogenisation.
In vivo Experimental Study on the Influence of Sodium Fluoride and Amoxicillin/Clavulanic Acid on the Minerals Composition of Dental Enamel
Authors: Mihalas Eugeniu , Ogodescu Alexandru , Balan Adriana , Aminov Liana , Decolli Yllka , Gavrila Laura , Savin Carmen
Published: February 2020

The aim of this study was to assess the morphological and chemical composition changes induced by the chronic intake of sodium fluoride (NaF) and Amoxicillin in mice enamel. 35 C57BL/6 adult male mice, were randomly divided into a control and 4 treatment groups (n = 7). After acclimatization, the experimental groups were simultaneously treated with 25 ppm (group 2 and 3) and 50ppm (group 4 and 5) of NaF, and 50mg/kg BW (group 2 and 4) and 100 mg/kg BW (group 3 and 5) of Amoxicillin as Amoxicillin/clavulanic acid (AMC). NaF was supplied through drinking water without restricting access, and AMC administered through subcutaneous injection, once per day, for 60 days. After harvesting, lower incisors� enamel was subjected to a scanning electron microscope (SEM) and to an energy dispersive X-ray analysis (EDX). In the treatment groups, SEM and EDX analysis in treatment groups showed an increasing trend of weight percentage (wt%) for C, N, O, F, Na and C/O, F/Fe ratio, and also a decreasing trend of wt% for P, Cl, Ca, Fe and Ca/P ratio. Morphological changes ranged from fissures and short grooves with pits-like appearance, in group 2 sometimes associated with limited demineralized areas looking like irregular scratches, up to demineralized areas extended in the outer enamel, which in group 5 gives the enamel the corroded look. The severity of the morphological changes in the mice enamel varied with the supplied dose of NaF and AMC, and had a uniform pattern in each experimental group. SEM analysis revealed a hypoplasia on the outer enamel and EDX analysis showed a hypomineralisation at the level of the outer enamel.
Novel Multiresidue Method for the Determination of Eight Trichothecene Mycotoxins in Pollen Samples Using QuEChERS-Based GC-MS/MS
Authors: Morariu Ionela Daniela , Avasilcai Liliana , Vieriu Madalina , Panainte Alina Diana , Bibire Nela
Published: February 2020

A simple multi-residue method based on QuEChERS-sample preparation was developed for the determination of eight trichothecene mycotoxins (nivalenol, fusarenon-x, diacetoxyscirpenol, 3-acetyl-deoxynivalenol, neosolaniol, deoxynivalenol, T-2 and HT-2 toxins) in pollen, using gas chromatography coupled with mass spectrometry. The developed method was validated by evaluating the following parameters: linearity, limit of quantification, matrix effect and precision of measurements. All mycotoxins showed good linearity. The method gave good recoveries (91-104%) with RSDs ] 11% for most of the analites (6 out of 8). The limits of quantification varied from 1 to 4�g�kg--1.
Research on the Mathematical Model for Developing the Oil Processing Company Environmental Strategies
Authors: Stefanescu Dan Paul , Chivu Oana Roxana , Babis Claudiu , Semenescu Augustin , Petrescu Valentin , Nen Madlena
Published: February 2020

As an attempt to define and characterize the elements required for the ERE systems optimal driving programs (objective of reaching future) in this paper are presented the results made the connection ENE-ECO in order to optimize the operating mode of the oil processing companies installations, depending on environmental and energy indicators. Strong companies in the field, studies (and even started applying) modern methods based on mathematical modeling and neural networks for the correlations between energy indicators and the environment on the one hand, and processing parameters on the other. In order to structure such an optimization methods, the paper presents a mathematical model and calculation program for determining energy and environmental indicators, depending on processing parameters, which become tools of own conception, applicable to any production installation. The study of these models, enable to identify the specific conditions, that must be satisfied for that economic processes to friendly coexist for long term with the environment, namely, to have an minimal impact, meaning that the resulting residues from the economic activity of the organization to be as less harmful as possible for the environment.
Chemo-physical Properties and Biomedical Applications of Hyaluronic Acid in Medicine
Authors: Vasile Danut , Iancu Raluca , Bogdanici Camelia , Ungureanu Emil , Ciobotea Dana , Ciuluvica Radu , Iancu George
Published: February 2020

Hyaluronic acid is a mucopolysaccharide encountered in most body fluids and extracellular matrix. The aim of our review is to summarize current evidence about chemico-physical properties of hyaluronic acid, highlighting biomedical applications of hyaluronan derivatives. It is a glycosaminoglycan made of repeating disaccharide units containing a carboxylate group, four hydroxyl groups and one carboxylate group, with hydrophilic properties. Its particular structure with multiple coils forming an entangled network results in unique pseudoplastic and viscoelastic characteristics. Its viscous and elastic behavior, depending on the applied strain, makes hyaluronan widely applicable in biomedical field. The large amount of functions and applications is determined by the physico-chemical properties, which allows a polymorphism of the hyaluronic acid structures depending on the molecular weight variations, concentration and ionic status. It is currently used in ophthalmology, orthopedics and rheumatology, in plastic surgery, surgery and otolaryngology as well. Already widely used in clinical practice, hyaluronic acid proves to be often the best solution for difficult medical problems. Future developments in nanomedicine and drug delivery linked to hyaluronic acid are emerging.
Electrochemical Behaviour of Titanium Based Biomaterials in Artificial Saliva
Authors: Earar Kamel , Grigore Camelia Ana , Budacu Cristian , Trinca Lucia Carmen , Mareci Daniel , Sincar Cerasela Dorina
Published: February 2020

In the last decade, new titanium alloys such as Ti6Al7Nb and Ti6Al7NbN have been developed in different areas of dentistry. It is known that mechanical/electrochemical interactions accelerate corrosion in implant alloys, and these interactions can be reduced by improving the modular component machining tolerances or by improving the corrosion resistance. The aim of this study was to compare the Ti6Al7Nb and Ti6Al7NbN alloys corrosion resistance in AFNOR artificial saliva. Due to the nitrogen diffusion, the Ti6Al7NbN alloy presents more pronounced grain structure than Ti6Al7Nb. In the electrochemical estimations the polarisation data were converted into instantaneous corrosion rate values (jcorr). The obtained passivation properties were comparable for both alloys. The EIS spectra were best fitted using an equivalent circuit (EC) which was consistent with the model of a two-layer structure for the passive film. The electrochemical and corrosion behaviour of Ti6Al7NbN increased the occurrence of the implant alloy�s electrochemical degradation.
Constructive Optimisation of the Propeller Type Mixing Devices Using the Virtual and Rapid Prototyping
Authors: Besnea Daniel , Spanu Alina , Prodea Iuliana Marlena , Tomescu Gheorghita , Panait Iolanda Constanta
Published: February 2020

The paper points out the advantages of rapid prototyping for improving the performances/constructive optimization of mixing devices used in process industries, here exemplified to propeller types ones. The multidisciplinary optimization of the propeller profile affords its design using parametric CAD methods. Starting from the mathematical curve equations proposed for the blade profile, it was determined its three-dimensional virtual model. The challenge has been focused on the variation of propeller pitch and external diameter. Three dimensional ranges were manufactured using the additive manufacturing process with Marker Boot 3D printer. The mixing performances were tested on the mixing equipment measuring the minimum rotational speed and the correspondent shaft torque for complete suspension achieved for each of the three models. The virtual and rapid prototyping method is newly proposed by the authors to obtain the basic data for scale up of the mixing systems, in the case of flexible production (of low quantities), in which both the nature and concentration of the constituents in the final product varies often. It is an efficient and
low cost method for the rapid identification of the optimal mixing device configuration, which contributes to the costs reduction and to the growing of the output.
Effect of Different Solutions on the Handmade Composite Materials
Authors: Pop Mihai Alin , Geaman Virgil , Radomir Irinel , Bedo Tibor , Milosan Ioan , Semenescu Augustin , Florea Bogdan , Chivu Oana Roxana
Published: February 2020

The paper presents the technology for obtaining the composite materials experimental samples � based on a resin reinforced with fiberglass, obtained manually and tested in terms of strength, corrosion behaviour and water absorption. In conducted experiments, these materials are recommended in order to produce finally: containers, tanks, hulls for boats, etc. It was also determined the effect of those solutions on the specimen�s surface. The experimental researches conducted and presented here are not studying and there are not made statements about the compatibility and the biological interaction between the composite material and solutions studied (distilled water, saline solution and acetic acid).
Impact of Cations Nature of Double Perovskite Ca2BWO6 on Structure and Magnetic Properties
Authors: Gorodea Ioana A. , Cornei Nicoleta , Sandu Ion
Published: February 2020

The aim of this work is to study the perovskite-type oxide Ca2BWO6 materials, where B = Cr, La and Sm, obtained by the sol�gel citrate-combustion method. The nature of the B-site cations influences the structure and properties of these compound. The synthesis progress was evaluated using X-ray diffraction and the structure of the samples was characterized by the Fourier transform infrared spectroscopy. In our case, the tolerance factor decrease with increasing of the ionic radius B leads to the structural distortion different from the cubic one. The magnetic properties were evaluated by a SQUID magnetometer and they are discussed in relationship with their compositions. From experimental data, it was noticed that all compound are ferromagnetic.
Effect of Essential Oil Mouthwash on Halitosis
Authors: Sabau Raluca , Ormenisan Alina , Monea Adriana , Szekely Melinda , Cosarca Adina , Ionescu Tudor Petru , Beresescu Gabriela , Dalai Camelia Elena
Published: February 2020

Halitosis is an embarrassing symptom with a significant social impact. Periodontal disease, tongue coating, interdental food impaction, and dental cavities are the predominant causative factors. The aim of this study is to evaluate the effect of essential oil mouthwash on halitosis. 30 patients aged between 16-25 were enrolled in this single-blind, parallel-group study. Informed consent was obtained. The following parameters were recorded: gingival index, plaque index, organoleptic breath assessment, and BANA test from tongue coating samples prior to treatment with essential oil mouthwash (group 1) or a placebo (group 2) at baseline and 28 days after the start of treatment. Histological examinations were performed from gingival tissue. There were significant differences (p[0.05) in plaque and gingival index after treatment with essential oil mouthwash compared to the placebo. The results provide a statistically significantly greater level of efficacy in controlling established plaque and gingival index after use of essential oil mouthwash. Therefore, it can be recommended in halitosis therapy.
The Adsorption of Cadmium and Zinc Ions from Waste Waters in Agricultural Argilaceous Soils
Authors: Pincovschi Irina , Neacsu Nicoleta , Modrogan Cristina , Stefan Mircea
Published: February 2020

The adsorption of cadmium and zinc ions from waste waters in agricultural argilaceaus soils have been studied, using a thermodynamic method in order to put in evidence the influence of adsorption conditions on adsorption degree. The adsorption isotherms, Langmuir and Freundlich, have been used to describe the adsorption equilibrium. The experimental data put in evidence that Cd2+ ions are more adsorbable (about 300 mmol/g) than Zn2+ ones (about 200 mmol/g). The Langmuir isotherms reflect more exactly the adsorption process of both Cd2+and Zn2+ ions, being recommended for thermodynamic parameters determination.
Comparative Analysis upon Action of Aqueous and Alcoholic Trigonella sp. Extracts on Fibroblasts Culture
Authors: Isaia Ioana Ancuta , Toth Csongor , Osser Gyongyi , Pallag Annamaria , Sirbu Vasile , Honiges Ana
Published: February 2020

Flow cytometry with its numerous advantages, has become indispensable for modern biochemistry research, being a highly efficient and sensitive in many areas, particularly in the fundamental or applied cellular biology. Flow cytometry has greatly contributed to the exploration of the cellular structure and functions, combining analytical and preparative aspects. In combination with the use of the probes (fluorochromes, fluorogenic substrates, monoclonal antibodies and lectins), the FCM enables multiple investigations for the characterization of cellular populations, the analysis of the cellular components (nucleic acids, proteins, intercellular and surface antigens, enzyme activities, membrane potential, mitochondrial activity, intracellular pH, ion flux and membrane fluidity). We chose to study the behavior of fibroblasts using flow cytometry, in terms of effects induced by the presence of extracts from Trigonella foenum graecum L.
The Uterus - a Progesterone Target Organ
Authors: Gheorghita Anda , Nemescu Dragos , Mihalceanu Elena , Plesea Condratovici Alina , Onofriescu Mircea
Published: February 2020

Progesterone is a steroid hormone synthetized from pregnenolone, a derivate of cholesterol, produced by the yellow body of the ovary and by the placenta during pregnancy. It is crucial for the evolution of the pregnancy, from preconception until delivery. It prepares the endometrium for implantation, supresses the immune response, inhibits the myometrium�s contractility and it can also make the myometrium sensitive to the action of beta-mimetic tocolytics. The vaginal administration of progesterone in various doses has proved effective in preventing premature birth in pregnant women with short cervix � 25mm during transvaginal ultrasound exam.
Research on the Economic Organization Environmental Impact
Authors: Stefanescu Dan Paul , Chivu Oana Roxana , Babis Claudiu , Semenescu Augustin , Gligor Alina
Published: February 2020

Any economic activity carried out by an organization, can generate a wide range of environmental implications. Particularly important, must be considered the activities that have a significant negative effect on the environment, meaning those which pollute. Being known the harmful effects of pollution on the human health, the paper presents two models of utmost importance, one of the material environment-economy interactions balance and the other of the material flows between environmental factors and socio-economic activities. The study of these models enable specific conditions that must be satisfied for the economic processes friendly coexist to the environment for long term, meaning to have a minimal impact in that the residues resulting from the economic activity of the organization to be as less harmful to the environment.
Study on the TNF-a, Il-1b and Il-6 Levels in Patients with Chronic Periodontitis and Cardiovascular Diseases
Authors: Nicolaiciuc Ovidiu , Mihai Constantin , Sufaru Irina Georgeta , Martu Ioana , Solomon Sorina Mihaela , Tatarciuc Diana , Budacu Cristian , Martu Silvia
Published: February 2020

Studies on the link between periodontal disease and atherosclerosis have generated conflicting results and the mechanisms underlying this relationship are incompletely understood. Therefore, this study aimed to assess the levels in serum and in gingival crevicular fluid (GCF) of TNF-a, IL-1b and IL-6, to clarify the possible link between periodontitis and hyperlipidemia, as well as the effects of conventional periodontal treatment through scaling and root surfacing on these pro-inflammatory molecules. The study was carried out on a total of 40 subjects divided into two main groups: the study group (n=26) and control group (n=14). The cases included patients with atherosclerosis with prescribed diet (D) or antilipemic therapy with a drug from the statin group (S). Controls (C) were selected from systemically healthy subjects with chronic periodontitis. Samples were performed from crevicular fluid and serum, by determining the initial and post-treatment of TNF-a, IL-1b and IL-6. For all groups there were significant serum decreases in TNF-a, IL-1b and IL-6 from baseline, and the decreases were more significant IL-1b for statin group. Significant decreases were found in the crevicular fluid for all cytokines. The decrease was most evident for IL-6 in the statin group. Combining antilipemic periodontal therapy and treatment can provide beneficial effects on metabolism and control of inflammatory atherosclerosis by lowering serum pro-inflammatory cytokines.
The Study of the Correlation Between the Level of Antioxidant, Enzyme Activity and Administration Zinc in Oxidative Stress Induced by Cyclophosphamide
Authors: Haliciu Ana Maria , Folescu Roxana , Zugun Florin , Strat Liliana , Poroch Vladimir , Zamfir Carmen Lacramioara
Published: February 2020

A well designed targeted chemotherapy is considered one of the goals of anticancer treatment, significantly improving the survival rate, but there is evidence suggesting it may presents significant drawbacks. Oxidative stress is frequently associated with chemotherapeutic agents, generating increased reactive oxygen species which may alter the female genital system. There are numerous opinions suggesting supplemental antioxidants in chemotherapy represent a positive therapeutic strategy. This study aim was to assess if antioxidants as zinc are able to preserve female rat�s genital system in cyclophosphamide (CP) - induced oxidative stress. In experiment there was used 21 female Wistar rats which were randomly divided in three groups: control, cyclophosphamide - administered group and cyclophosphamide-ZnCl2 administered group. After four weeks, blood was collected to determine malondialdehyde (MDA) level and glutathione peroxidase (GPx) activity. Our results suggests that zinc reduces the deleterious effect of oxidative stress on female rats genital system, the decrease of MDA level together with GPx increase being considered as a result of Zn administration.
Development of a New Method for Determination of the Oil Content from Microalgae Lipid Fraction
Authors: Galan Ana Maria , Calinescu Ioan , Radu Elena , Oprescu Elena Emilia , Vasilievici Gabriel , Velea Sanda
Published: February 2020

The purpose of this study was to develop a method for rapid quantitative and qualitative determination of the oil from microalgae lipid fraction obtained from Nannochloris sp biomass. The lipid fraction was first refluxed with 4% KOH in MeOH (60, 90, 120 min), followed by reaction with 20% BF3 in MeOH, using different times of reflux (90,120, 150 min) for each time of reflux with 4% KOH in MeOH. The FAME samples were analyzed by GC-MS analysis. 120 min reflux with 4% KOH in MeOH, 90 min with 20% BF3 in MeOH and a ratio lipid fraction: 4% KOH in MeOH: 20% BF3 in MeOH=1:20:27, were required to obtain the higher percent of oil in the microalgae lipid fraction. The relevance of the method developed was proved by TGA analysis and by transesterification of a sunflower oil sample in the same conditions.
Characterization of the Specificity in Three Commercial Dental Ceramic Powders
Authors: Manolea Horia , Opri Mirela , Cioatera Nicoleta , Voinea Adriana , Rica Radu , Tora Madalina , Popescu Sanda Mihaela , Dascalu Ionela Teodora
Published: February 2020

The aim of this study was to present and discuss the characteristics of three ceramic powders as well as the sintered material from the three commercial dental ceramics produced by Vita Zahnfabrik, Germany (VM13 and VMK Master, used for veneering metal frameworks, respectivelly VM9 used for veneering zirconia frameworks). An X-ray diffraction (XRD) analysis was performed, Raman spectra were recorded and the morphology of the samples was evidenced by using a high resolution scanning electron microscope, equipped with an EDXS detector. The results of this study corroborated with the presented literature data helps practitioners to better understand the interaction of these biomaterials with oral tissues, and, also helps researchers to modify the properties of ceramics for a better integration in the intraoral condition.
The Effects of Hg2+ on Endothelial Function in Electronic Cigarette Smokers with Coronary Artery Disease
Authors: Balint Germaine Savoiu , Boruga Ovidiu , Iovanescu Gheorghe , Popovici Ramona Amina , Bolintineanu Sorin Lucian , Mihaescu Rodica , Popoiu Calin Marius , Boia Eugen , Petrus Alexandra , Andoni Mihaiela
Published: February 2020

The present available data on the harmful effects of electronic cigarettes (EC) is inconsistent and contradicting. Even though EC is considered a healthier alternative to the traditional cigarettes, several studies reported a large range of toxic compounds. The objective of this study is to determine whether the mercury found in the solutions used for electronic cigarettes is involved in the initiation and aggravation of endothelial dysfunction found in smoking persons with coronary artery disease (CAD). Endothelial function was evaluated by performing organ bath studies of vascular rings from patients with CAD, and was determined as a response to cumulative doses of endothelial-dependent/independent vasodilators, in the presence of Hg2+. Hg2+ extraction was realised using ion exchanging resin PUROLITE S920 from the liquid solution used in EC. The results of this study suggests that Hg2+ may be responsible for the aggravation of the endothelial dysfunction found in smoker of EC patients with CAD.
Hartman Perdok Method Applied to A2BSi2O7 and AB2O6 Types of Microcrystals and the Concept of Fractional Charges
Authors: Heghes Alina , Nicolov Mirela , Duse Adina Octavia , Dragos Dan , Zsabadai Zoltan , Bolintineanu Sorin , Marti Daniela
Published: February 2020

Using the concept of Fractional Charges were calculate the attachment energies and was simulated the growth form of quartz crystals in the past. In this paper , by using the concept of normal and fractional charges in the system for A2BSi2O7 and AB2O6 types of crystals, will be computed the attachment energies and it will be done the conclusions of influences of fractional charges in the system for energies calculations the first step in Hartman Perdok Method applied to microcrystals.
Vascular Reactivity and Proinflammatory Cytokines in the Obese Children
Authors: Popescu Laura Anca , Virgolici Bogdana , Stefan Daciana Costina Andrada , Lixandru Daniela , Timnea Olivia , Virgolici Horia , Oraseanu Dumitru , Sinescu Crina , Mohora Maria
Published: February 2020

The aim of this study was to evaluate the relation between inflammatory markers and the preatherosclerotic marker - flow mediated dilation (FMD). Thirty obese children (10-16 years old) and twenty controls were involved. The plasma inflammatory markers: CRP, fibrinogen, leptin, TNF-a, IL-6 were measured. Ultrasounds were used for FMD measurement, chemiluminescence for monocyte respiratory burst (RB), ELISA for C peptide and spectrophotometry for usual parameters. In the obese children versus the lean ones, the FMD was lower (p[0.001), the plasma values for TNF-a were similar (1.68 pg/mL vs 1.54 pg/mL), while plasma IL-6 was increased (4.01 pg/mL vs. 2.02 pg/mL, p[0.05). These cytokines were negatively correlated with FMD (r=-0.42, p[0.05) and positively with RB (r=50, p[0.05). The FMD was negatively correlated (p[0.05) with the values for diastolic blood pressure (r = -0.47), waist circumference (r = -0.55), uric acid (r = -0.47) and atherosclerotic index (r = -0.37). In conclusion, in the obese children, inflammation, dyslipidaemia, blood pressure and oxidative stress act in a cluster reducing the elasticity of the vessel walls.
Study on the Influence of Soil and Fertilization on Amino Acid Content in Oil Linen
Authors: Pop Georgeta , Alexa Ersilia , Iancu Tiberiu , Imbrea Florin , Laza Adrian
Published: February 2020

Research results on oil linen (Linum usitatissimum L.) point out the importance of this crop not only as an oil plant but also as a plant with multiple opportunities of diversification. The experiment was set at the Didactic and Research Station within the Banat�s University of Agricultural Sciences and Veterinary Medicine King Michael I of Romania from Timisoara. The goal of this paper is to analyse the impact of soil and fertilization on amino acid content level and structure in oil flax vegetal protein. Cultivar plays a determining role on the content of amino acids in oil flax vegetal protein: the sum of amino acids ranges between 16.21 and 22.44 g/100 g of grits. Fertilization changes the amount of amino acids: the sum of amino acids ranges between 17.08 and 23.32 g/100 g of grits. Fertilization also determines changes of the level and structure of amino acids in oil flax protein.
On the Role of Chemical and Molecular Biology in Inflammation Research
Authors: Macovei Luana Andreea , Birsan Magdalena , Teodor Vlad Ioan , Cristofor Ana Caterina , Ioanid Nicoleta , Rezus Elena
Published: February 2020

Inflammation is an elaborate reflex response of the body to the action of harmful agents. This reaction manifests itself in the form of functional and structural changes of vascular tissues. The inflammatory response is the result of the human evolutionary process. It has three main stages, which are closely related to each other and evolve simultaneously: tissue dystrophy (alteration); impairment of blood circulation (transudation of fluid and migration of leukocytes) and multiplication of cellular elements (proliferation). These phenomena express both a disturbance of biological activity in body tissues and the defense mechanisms to restore the damaged areas. There are two interrelated processes which are often inseparable from each other in the inflammatory response. First, there is the pathological process itself, the tissue damage in form of dystrophy, necrobiosis or necrosis. Second, there is the physiological mechanism of defense, the process of recovery or the physiological response against the disease, manifested as exudation, phagocytosis and proliferation. Simultaneity of both processes is characteristic to inflammatory processes.
Assessment of Outdoor Pollution with Submicrometric and Fine Particulate Matter in Ploiesti City, Romania
Authors: Iordache Stefania , Dunea Daniel , Ianache Cornel , Predescu Laurentiu , Dumitru Dumitru
Published: February 2020

Airborne particulate matter (PM) is a major environmental problem in urban areas mainly because of its demonstrated impact on human health. The present work aimed to assess the outdoor pollution to fine (PM2.5), and submicrometric (PM1) particulate matter that includes the ultrafine fraction - UFP), in Ploiesti city, which is a major urban-industrial area in the Southeast of Romania. This is the first study in an urban area of Romania that analyzes the spatiotemporal variation of PM2.5 and PM1. Particulate matter samples collected in sequential monitoring campaigns performed in 2015 were investigated using 12 relevant sampling points. A precision optical portable monitoring system with a laser beam (DusttrakTM DRX 8533EP) was used for PM assessments.. It was observed that Ploiesti inner city presented �moderate� and �unhealthy for sensitive groups� conditions for particulate pollution with PM2.5 depending on the area of the city. The difference between the PM10 and PM1 medians of all sampling points was only 2.2 �g�m-3, PM4 and PM1 of 1.5 �g�m-3, and PM2.5 and PM1 of 0.8 �g�m-3 respectively (p ] 0.05 � DL5% = �5.8 �g m-3). The correlation between the PM fractions was very significant (p [ 0.01; r = 0.996). The results pointed out that PM1, which has an increased impact on human health, because it includes the UFP, was the most frequent fraction in Ploiesti inner city.
A Complex Analysis Employing ARIMA Model and Statistical Methods on Air Pollutants Recorded in Ploiesti, Romania
Authors: Pohoata Alin , Lungu Emil
Published: February 2020

Air pollution is an everyday issue, very relevant to public authorities, requiring control and monitoring to provide data for decision-making policies. The objective of this study was to evaluate the air quality in Ploiesti city, Romania and to observe the advantages and limitations of the some statistical methods used in forecasting air quality. Data for six air quality parameters collected at monitoring stations in Ploiesti during the 2013 year were statistically analyzed. Principal component analysis (PCA) was used to provide a relevant description in factors that can be explained in terms of different sources of air pollution. The measured pollutants data were statistically analyzed using the auto-regressive integrated moving average (ARIMA) method in order to assess the efficiency of using this method in forecasting the environmental air quality. The results revealed that ARIMA method has some limitations and do not produce satisfactory results for certain air pollutants such as PM10 and CO, even the forecasted period is short. By comparison, the ARIMA model obtained for NOx , NO2 , or O3 time series, provides good results, with relative errors around 5%.
Aerosol Source Assessment Based on Organic Chemical Markers
Authors: Marmureanu Luminita , Vasilescu Jeni , Marin Cristina , Ene Dragos
Published: February 2020

The aim of this paper is to identify the potential sources of fine aerosols in Magurele, Romania, during an intensive campaign of 2 weeks performed in August-September 2014, based on mass concentration, species proportions and specific chemical markers.Major contributors to submicronic non-refractory aerosols are organic species, ammonium and sulphate. The inorganic species have been present as salts of ammonium nitrate and ammonium sulphate, while strong influence of traffic related source has been identified during the entire measurements period from organic species analysis. Other contributions besides those mentioned above are biomass burning and two different oxidized organic aerosols.
An Urban Air Pollution Early Warning System Based on PM2.5 Prediction Applied in Ploiesti City
Authors: Oprea Mihaela , Olteanu Marius , Ianache Radu Teodor
Published: February 2020

Fine particulate matter with a diameter less than 2.5 �m (i.e. PM2.5) is an air pollutant of special concern for urban areas due to its potential significant negative effects on human health, especially on children and elderly people. In order to reduce these effects, new tools based on PM2.5 monitoring infrastructures tailored to specific urban regions are needed by the local and regional environmental management systems for the provision of an expert support to decision makers in air quality planning for cities and also, to inform in real time the vulnerable population when PM2.5 related air pollution episodes occur. The paper focuses on urban air pollution early warning based on PM2.5 prediction. It describes the methodology used, the prediction approach, and the experimental system developed under the ROKIDAIR project for the analysis of PM2.5 air pollution level, health impact assessment and early warning of sensitive people in the Ploiesti city. The PM2.5 concentration evolution prediction is correlated with PM2.5 air pollution and health effects analysis, and the final result is processed by the ROKIDAIR Early Warning System (EWS) and sent as a message to the affected population via email or SMS. ROKIDAIR EWS is included in the ROKIDAIR decision support system.
Study of Phosphocalcic Glasses SiO2-CaO-P2O5 System with and without Silver. I. Synthesis of glasses and characterization by WD-XRF and XRD
Authors: Avram Daniela , Angelescu Nicolae , Ungureanu Dan Nicolae , Ionita Ionica , Gheboianu Anca , Bancuta Iulian
Published: February 2020

Synthesis glasses biocompatible made a great step forward in the last few decades, moving from traditional methods of supercooling melts and casting them to the modern, using the action of neutrons, mechanical and deposition in thin layers by different techniques, glass transition or sol-gel technique. In this paper it is presented sol-gel synthesis of two glasses silicofosfocalcic composition of SiO2-CaO-P2O5 system with and without silver ions.The investigation of chemical elemental composition of researched glasses, as well as the de novo synthesis of hydroxyapatite, post dip, was done by using modern methods used for this purpose.
The Protective Effect of HDL-Cholesterol in Patients with Essential Hypertension
Authors: Savoiu Balint Germaine , Iovanescu Gheorghe , Stanca Horia , Popoiu Calin Marius , Boia Eugen , Popovici Ramona Amina , Bolintineanu Sorin Lucian
Published: February 2020

High blood pressure (HPB) is considered a major health problem affecting more than one billion people worldwide. Hypertension is the most common cardiovascular disorder that increases the risk of cardiovascular morbidity and mortality. HDL-cholesterol, considered to be an independent risk factor for cardiovascular events, presents pleiotropic effects that can influence arterial status and blood pressure. The aim of this study was to determine the correlation between HDL-cholesterol levels and blood pressure in normotensive and hypertensive patients (untreated and 1-month treated with statins) and to evaluate the arterial stiffness as a marker of endothelial dysfunction in these patients.
The Use of Colour Codes in Ceramics Build-up for Achievement Esthetic Anterior Restorations
Authors: Rica Radu , Dascalu Ionela Teodora , Tuculina Mihaela Jana , Rica Ana Maria , Diaconu Oana Andreea , Moraru Iren , Rotaru Vlad , Manolea Horia
Published: February 2020

The ability to mimic the optical characteristics of enamel and dentin, the excellent biocompatibility and the chemical durability of dental ceramics are the reason reasons why this topic is considered of great importance in dentistry. The aim of this study was to highlight the differences during the process of manufacturing anterior esthetic restorations, i.e. the proper selection of color shades of dental ceramics and their correct deposition.Techniques for performing aesthetic ceramic restorations are influenced by the experience of the dental technician and their skills in realizing the restoration, which should be as little complicated, even if the dental ceramic powders has coded shades of color. Some dental technicians prefer their own color labels in order to facilitate their work and to modify or to highlight some effects of the powders, during the dental ceramics build-up. Naturalness of eight anterior restorations was obtained by alternating the opalescent base layer of the dental ceramic and the fluorescence of crystalline layers subsequently applied over opaque. Different translucent type of ceramic layers was used in order to create the true aspect of the incisal area, with a natural halo appearance. The increasing expectations of the patients in aesthetic restoration of anterior area of dental arches demand a complex build-up of the porcelain layers and this technique requires that the dental technician to possess special skills for obtaining a successful result.
Phase Behaviour Analysis of the Water from Natural Gas Along the Pipelines
Authors: Eparu Cristian , Neacsu Sorin , Ionescu Eugen Mihail , Albulescu Mihai , Prundurel Alina
Published: February 2020

Based on the methodology for determining the liquid-vapor equilibrium conditions for wet gas, the paper presents a model of water phase behavior for the water existing in gas transmitted through pipelines, model based on Simone simulator. By using this model, we tried to correlate the measured data of humidity with the values of gas transmission parameters and with the pipeline profile.
Thermal Characterization of Extracts Obtained from Different Parts of Nigella damascena (Ranunculaceae) by TG and DSC
Authors: Toma Claudia Crina , Neag Teodora Alina , Tita Bogdan
Published: February 2020

The increased search for herbal products has generated an increasing interest in improving the quality control of extracts by pharmaceutical industry since these are raw materials of great importance by their quality and versatility. Thermal analysis such as thermogravimetry (TG) is a technique of high sensitivity, reproductibility and rapid response to variations in mass, obtaining results related to the composition and thermal stability of the sample, being important to the characterization of raw plants. Thermogravimetric techniques and differential scaning calorimetry (DSC) used for the study of pre-formulation of drug-excipient compatibility have been gaining importance. These techniques are being used for the verification of possible interactions between drugs and excipients. Aiming at studying the behavior of a plant extract, using these thermoanalytical techniques, the plant species Nigella damascena semen and Nigella damascena herba was used. This plant has healing and anti-inflammatory properties. The methodology for obtaining the extract followed the European Pharmacopoeia methodology. The TG and DSC curves were obtained under nitrogen and air atmosphere (20 mL/min) at a heating rate of 10�C/min. The TG and DSC tests were analyzed within a temperature range from 25 to 1000�C.
The Spectrophotometric and Tensiometric Study of Interaction Between Nonionic Surfactants with Acid Dye
Authors: Moater Elena Irina , Radulescu Cristiana , Ionita Ionica
Published: February 2020

The study of the interaction between nonionic surfactants and acid dyes is very important in clarifying the mechanism of wool dyeing and colors preservation and also for the washing conditions determination.
This paper presents the spectrophotometric and tensiometric data of the interaction between the alkyl polyglucosides surfactants class with new synthesized dye, from the class of azoic dyes derived from 3H-aza-1-oxa-2H-tioxo-5,8-fenalendisulfonic acid. A multiplicity of transitions is observed, when the surface tension of aqueous solutions of nonionic surfactant (APG) in the presence of the acid dye, which interacts strongly with nonionic surfactant to from a dye-surfactant complex, is measured at a constant concentration of the dye and plotted as a function of surfactant concentration. The formation of some surfactant- dye complexes was made evident in the different molecular ratios in the submicellar zone compared to the micellar zone of concentration of the surfactant. There au different equilibrium in the system which compete one another over a large scale of surfactant concentration (adsorption, micellization, small complex formation, large complex �mixed micelles formation).
Ultrasonic Irradiation a Chlorinated Organic Compounds (Trichloroethylene, Tetrachloroethene, 1, 1, 2-Trichloroethane) from Water
Authors: Iordache Mihaela , Popescu Luisa Roxana , Pascu Luoana Florentina , Iordache Ioan , Marinoiu Adriana
Published: February 2020

The paper describe the sonochemical degradation of organochlorine compounds (Trichloroethylene, Tetrachloroethene and 1, 1, 2-Trichloroethane) from aqueous solutions. The experiments was realized with two types of equipment: ultrasound bath UCD-150 and sonotrode UP 200 Ht. The experimental results showed high efficient removal for all three compounds: Tetrachloroethene 93.8%, 1, 1, 2-Trichloroethane 92.9% and Trichloroethylene 86.6% in bath ultrasound treatment after 50 min. The ultrasound efficiency treatment depend by the sonotronde diameter. The degradation of Trichlorethylene and 1, 1, 2 -Trichloroethane is much better for sonotrode with 14 mm diameter (92.1% respectively 92.7%) than for sonotrode with 40 mm diameter (71.9% and 61.6%), while for Tetrachloroethene values were very close, 88.7% respectively 89.4% for the same above mentioned diameters.
Use of Methadone as First Line Strong Opioid for Moderate-Severe Pain
Authors: Mosoiu Daniela , Sporis Mariana , Stanculeanu Dana Lucia , Toader Elena , Poroch Vladimir , Boanca Mihaela , Simion Laurentiu
Published: February 2020

The present study evaluates the use of methadone in patients with advanced cancer and moderately-severe pain under palliative care at home over a period of 5 years, from 1996 to 2000. We calculated the index for methadone dosage increase (as a percentage and value in milligrams). Of the 1,079 patients cared for, 247 (22.89%) received methadone treatment: 126 from the very beginning, average dose of 15 mg / day (5- 50), and in 121 patients treatment with methadone was initiated at a later moment during the period they were cared for (5- 40). The median period of time of methadone administration was 27 days (1-416), the median dose of methadone at the moment of treatment discontinuation being 20 mg (5-60). The main reason for methadone treatment discontinuation was impossibility of oral administration (49.8% in terminal stages, 7.3% presenting nausea, vomiting), and 62.3% showed no side effects. Dosage increase index was 0.33 mg, 2.33% respectively. Methadone has been used mainly as a potent first line opioid, and has been shown to be effective and safe.
Osteonecrosis of the Mandible Associated with Bisphosphonate Treatment
Authors: Popescu Eugenia , Ciofu Mihai Liviu , Popescu Dragos Cristian , Agop Forna Doriana , Martu Silvia
Published: February 2020

This study analyzes 35 patients with bisphosphonate-related osteonecrosis of the mandible (BRONJ) diagnosed and treated in the Oral and Maxillofacial Surgery Clinic of St. Spiridon Hospital Iasi. The inclusion criteria were in line with the recommendations of the American Association of Oral and Maxillofacial Surgery (AAOMS). The analysis included the underlying disease, the type of bisphosphonate and the route of administration, the duration of treatment as well as the osteonecrosis triggering factor. Surgery was consistent with the condition of the disease, ranging from debridement and sequestrectomy to alveolar marginal and even segmental bone resections. The results of the study were similar with the data from the literature suggesting that the condition is more common in the lower jaw compared to the upper jaw, and the main risk factors are dental extraction and intravenous bisphosphonate administration.