bluuebunny/crossref_metadata_2025 huggingface dataset:
RE-LAYOUT SHOPFLOOR DEPARTMENT AT RETAIL COMPANY TO OPTIMIZE THE INITIAL LAYOUT, MATERIAL HANDLING REDUCTION, AND TRANSPORTATION WASTE MINIMIZATION USING BLOCPLAN ALGORITHM
Authors: Wardhana Kresna Adji Setya , Cahyo Winda Nur
Published: January 2025

Starcorss shopfloor employee (receiving and warehousing department) at headquarter stated on very high level of mental workload while high season compared while low season. Based on this consideration, the business owner asked the author personally to develop a new layout for shopfloor department as mitigation for mental workload based on previous research recommendation. Most likely 3 month the author has direct observed and proposed am optimized shopfloor layout with BLOCPLAN Algorithm approach. The proposal also considers about how to reduce waste activities on the shopfloor regarding material handling.
Technological innovation and social construction of Makassar film industry’s production and distribution
Authors: Puspitasari Lilis , Bajari Atwar , Hidayat Dadang Rahmat , Cho Sung Kyum
Published: January 2025

Background: Cinematography has evolved significantly with technological advancements. In Makassar, Indonesia, film distribution faced challenges due to limited cinemas and competition with imported films. The research explores how technology has transformed film production, distribution, and promotion in Makassar. It addresses gaps in understanding regional cinema’s adaptation to technological changes. Purpose: This research aimed to examine the role of technology in transforming film production and distribution around Makassar. Methods: The study employed qualitative research methods with a case study approach. Data was collected through interviews and observation with key figures in Makassar’s film industry, including producers, directors, and editors. The research applied the Social Construction of Technology (SCoT) theory to analyze how social factors shaped and influenced technology. Results: In pre-production, technology helps with audience research and visual concept design; In the production stage, digital cameras increase image quality and flexibility. In post-production, advanced software allows for better editing and visual effects despite limited local experts; In distribution, it expanded from theaters to streaming platforms, reaching a wider audience. All stages benefit from better collaboration through digital tools. Conclusion: This study found that technology has significantly impacted all stages of filmmaking in Makassar. At the pre-production stage, digital tools facilitate collaboration and audience research. During production, advanced cameras and equipment enhance visual quality and creative possibilities. Post-production benefits from sophisticated editing software, although some processes still require expertise outside the region. Film distribution does not rely on movie theatres; it is distributed through platforms like Netflix, Disney+, Hulu, and Prime Video. Implications: Specifically, findings suggest that regional filmmakers should invest in digital skills and explore diverse distribution channels. Theoretically, the study contributes to understanding how SCoT applies in regional film contexts. It highlights the importance of considering local social dynamics in technological adoption within creative industries.
Communication strategy of Wat Phra Sri Maha Uma Devi as a Hindu Tourism Destination in Bangkok
Authors: Boonplook Kunyapas , Boonyanmetaporn Wassida
Published: January 2025

Background: Wat Phra Sri Maha Uma Devi, commonly known as Wat Khaek Silom, is a popular and important Hindu temple in Bangkok, serving as a tourist attraction. Through communication and promotion efforts through digital media and collaborating with various parties to create attractive religious tourism. Despite its popularity, research on effective communication strategies to increase its attractiveness as a religious tourism destination is limited. Purpose: This study aims to analyze and develop effective communication strategies to promote Wat Phra Sri Maha Uma Devi as a Hindu tourist destination in Bangkok. The focus of the research is on communication strategies that are carried out through integrating cultural and religious values, as well as utilizing the use of digital communication media. Methods: This research employed a qualitative approach using a case study methodology, including interviews and participatory observations of temple management, tourists, and the local community. This approach was taken to gain a thorough understanding of the experiences, views, and challenges in managing religious tourism. Results: The findings highlight that effective communication, such as the use of digital communication media platforms and multilingual educational materials, significantly enhances the tourist experience and promotes sustainable tourism. The challenges faced are maintaining the authenticity of the temples while meeting the growing demands of tourism. Conclusion: Wat Phra Sri Maha Uma Devi has successfully integrated religious and cultural elements with effective communication strategies, making it a major tourist destination for Hindus. Implications: The findings of this study provide insights for tourism authorities and temple management to develop sustainable communication strategies that balance cultural preservation with commercial development.
Factors influencing and moderating the satisfaction with banking services: A case study in Hungary
Authors: Vinkóczi Tamás , Németh Anikó , Dávid Lóránt Dénes
Published: January 2025

The ongoing dissemination of globalization and digitalization may suggest that personal relationships are becoming less crucial in the context of retail banking and financial services. In Hungary, in addition to private banking, which is associated with high income levels, personal banking also plays an important role. The objective of this study is to develop a model that can identify the factors that determine customer satisfaction and their relative importance. Furthermore, the aim is to incorporate gender and age as moderator variables to identify demographic differences in satisfaction. The analysis was conducted via a questionnaire survey in October to November 2023 employing a purposive sampling approach in a university environment, as the respondents are likely to possess the highest level of existing financial knowledge within this population. The 214 valid responses were analyzed using the Partial Least Squares Structural Equation Modeling (PLS-SEM) approach, with the objective of contributing to the development of theory in this field of study. The results demonstrate that perception (β = 0.519) and reliability (β = 0.253) collectively explained 51.8% of the variance in satisfaction. Moreover, the results indicate that perception accounts for 49.2% of the variance in reliability, suggesting the existence of an indirect effect on satisfaction. Therefore, the findings suggest that, despite the advent of digital banking, face to face service remains a pertinent concern in Hungary, and financial institutions should prioritize the factors that shape customer satisfaction. The study contributes to the literature and to the development of customer loyalty strategies for banks based on these findings.
Classical Isoperimetric Theorem
Authors: Nakasho Kazuhisa , Shidama Yasunari
Published: January 2025

In this article we present the Mizar proof of the isoperimetric theorem (one of the theorems listed among Wiedijk’s Top 100 mathematical theorems), inspired by Peter D. Lax’s paper “A Short Path to the Shortest Path”. Using relatively simple formal apparatus of continuous and differentiable functions, we show that among all curves of fixed length connecting two points on the x-axis, a semicircle is the curve which maximizes the area between the curve and the x-axis.
Fundamentals of Finitary Proofs
Authors: Huuskonen Taneli
Published: January 2025

An abstract, generic textbook notion of a finitary proof and some of its basic properties are presented, using the Mizar system. A general form of Lindenbaum’s lemma is included.
Higher-Order Differentiation and Inverse Function Theorem in Real Normed Spaces
Authors: Nakasho Kazuhisa , Shidama Yasunari
Published: January 2025

This article extends the formalization of the theory of differentiation in real normed spaces in the Mizar system. The focus is on higher-order derivatives and the inverse function theorem. Additionally, we encode the differentiability of the inversion operator on invertible linear operators.
Audit Report Lag and Audit Fee Analysis Before and After the Implementation of Key Audit Matters in Indonesia
Authors: Loverita Vindy Felycia , Januarti Indira
Published: January 2025

This study aims to examine the differences in audit report lag and audit fees in the year before and after the implementation of Key Audit Matters (KAM) in independent auditor reports. Provisions regarding KAM disclosure in Indonesia began with the 2022 financial reports. The population for this study includes all companies listed on the Indonesian Stock Exchange for the years 2021 and 2022. The dataset used in this research comprises 966 observations, consisting of 483 companies for each period (2021 and 2022). Using the Wilcoxon signed-rank test, the results indicate that the audit report lag was longer in the year before KAM communication compared to the year after its implementation. This finding could be attributed to the impact of the COVID-19 pandemic and the additional one-month extension granted by the Financial Services Authority (OJK) for the submission of audited financial reports. The results show that audit fees increased following the implementation of KAM. This suggests that auditors incur higher costs when required to include KAM in their audit opinions. This research highlights the implications of KAM communication on audit processes, including timeframes and associated costs.
#023 Fibrina rica em plaquetas na cirurgia de recobrimento radicular: uma abordagem promissora
Authors:   ULS São João, Maurício Ana , Maia Henrique ,   ULS São João, Barbosa José ,   ULS São João, Lopes Constança ,   ULS São João, Alves Joana ,   ULS São João, Santos Pedro ,   ULS São João
Published: January 2025

Introdução: A recessão gengival designa-se como a migração apical da margem gengival em relação à junção amelocementária, com exposição radicular concomitante. Apresenta etiologia multifatorial: fenótipo gengival, técnica de
escovagem, presença de cáries cervicais, tratamentos ortodônticos e predisposição genética. A prevalência é de cerca
de 45%, associando-se a sintomas de hipersensibilidade,
mobilidade dentária e compromisso estético. A cirurgia de
recobrimento radicular tem demonstrado eficácia no seu
tratamento, prevenindo a perda dentária. O retalho de avanço coronal com enxerto de tecido conjuntivo é a técnica gold
standard, tendo como limitações a necessidade de uma área
dadora e quantidade limitada de tecido conjuntivo disponível. Surgiu assim a necessidade de explorar alternativas, tais
como as matrizes de regeneração dérmica, de colagénio e
de concentrados de plaquetas. Este relato apresenta um
caso de recobrimento radicular, utilizando fibrina rica em
plaquetas e leucócitos e retalho de avanço coronal. Descrição do Caso Clínico: Doente do sexo feminino de 33 anos,
com esclerose múltipla, sob terapêutica com agente biológico. Apresenta queixas de sensibilidade dentária em relação com dente 44 e insatisfação estética por recessão gengival em todos os quadrantes. Realizou previamente
enxerto de gengiva livre no 1º quadrante, com falência. Ao
exame objetivo, boa higiene oral, fenótipo gengival fino,
dente 44 com recessão gengival classe II de Miller, 9 milímetros, bolsa periodontal mesiovestibular de 5 milímetros,
mobilidade grau I, hemorragia à sondagem e freio gengival
acessório mesiovestibular. Face às comorbilidades e antecedentes cirúrgicos, realizou-se frenectomia e cirurgia de recobrimento radicular, com retalho de avanço coronal e
membrana de fibrina rica em plaquetas e leucócitos. No 1º
mês pós-operatório, a doente apresentou ganho da espessura gengival e recobrimento radicular parcial, ganho de 4
milímetros. Discussão e Conclusões: A fibrina rica em plaquetas e leucócitos permite a formação de membranas com
propriedades promotoras da cicatrização tecidual, por libertação local de fatores de crescimento derivados de plaquetas e fatores de crescimento endotelial vascular. Proporciona também um suporte estrutural reabsorvível, e um
balanço custo-eficiência bastante satisfatório. As características mencionadas tornam esta técnica uma alternativa
viável para o enxerto de tecido conjuntivo supletivamente
à cirurgia de retalho de avanço coronal.
Evaluation of ocular blood flow by Doppler Ultrasound in patients with glaucoma
Authors: Malishevskaya T. N. , Kiseleva T. N. , Renzyak E. V.
Published: January 2025

Primary open-angle glaucoma (POAG) is a neurodegenerative disease causing glaucomatous damage of the optic nerve with characteristic visual field defects. Vascular theory of the glaucoma pathogenesis considers glaucomatous optic neuropathy (GON) as a result of changes in impaired ocular blood flow (OBF). Ultrasound examination with the assessment of OBF using multifunctional ultrasonic diagnostic devices is used for evaluation of hemodynamic parameters in the retrobulbar vessels: ophthalmic artery (OA), central retinal artery (CRA) and short posterior ciliary arteries (sPCA). This review presents the results of ocular blood flow studies using Doppler Ultrasound methods in patients with POAG and normal tension glaucoma (NTG). Many researchers have emphasized the important role of these methods in diagnosing and monitoring the optic nerve damage progression in glaucoma. In clinical practice, the standardization of the vascular Doppler Ultrasound technique and development of a suitable study protocol should improve the informativeness of the method and obtain reliable and reproducible results.
Features of nonlinear dynamic processes of blood microcirculation in patients with obliterating atherosclerosis of lower limbs and diabetes mellitus 2 types
Authors: Streltsova N. N. , Vasiliev A. P.
Published: January 2025

Aim. To study the nature of shifts in the nonlinear dynamics parameters of blood microcirculation (BMC) in patients with obliterating atherosclerosis of the arteries of the lower limbs (OAALL) and concomitant diabetes mellitus (DM).

Materials and Methods. Sixty male patients with OAALL, median age 63.0 [59.0; 68.0] years, who were divided into 2 groups equal in age and basic clinical and anamnestic data, were studied: 1 – patients without DM (n=45) and 2 – with concomitant DM (n=15). Nonlinear dynamic processes of BMC of the foot skin of the affected limb were assessed by laser Doppler flowmetry. The study included determination of fractal dimension (Do, R/S), entropy (Ho, Hi) and phase portrait analysis (D2, D2H).

Results. The analysis of nonlinear-dynamic processes of BMC has shown a statistically significant decrease of median values of fractal dimension parameters (Do, R/S) by 30 % and entropy indices (Hi) by 33 % in OAALL patients with concomitant DM in comparison with the group of patients without DM. This indicates a decrease in the number of factors involved in the coordination of microvascular system activity, growth of its functional rigidity, limitation of situational lability and reduction of chaotic behavior.

Conclusion. The study of nonlinear dynamics parameters provides additional data of important clinical significance for the assessment of pathophysiology of the disease. The results obtained indicate a reduction in the reserve of adaptive regulation of BMC in the combination of OAALL with DM and are associated with a worse prognosis of the disease.
Artist's Statement: REBIRTH
Authors: Walton Angelica
Published: January 2025

Artist’s Statement for the cover art of the Interdisciplinary Journal of Partnership Studies, Volume 11, Issue 2: Rebirth. Mixed Media
Leaving Before Completing: How Course Withdrawal Predicts College Student Success
Authors: Bicak Ibrahim , Taylor Z.W.
Published: January 2025

Course withdrawal is common among college students, but scant empirical research has explored the effects of course withdrawal on student outcomes (e.g., persistence, degree attainment). By using statewide administrative data from Texas (N=605,362), we estimate the relationship between course withdrawal and student outcomes, finding course withdrawal rates usually affect time to degree and degree attainment. We also find that time to degree increases as withdrawal rate increases, as the more students withdraw from courses, the fewer excess credits they accumulate. We also discover nuance in degree attainment, as data suggests a 4% withdrawal rate (about one or two courses withdrawn) may start erosion of a student’s degree progress, evidenced by the data in this study. Moreover, further course withdrawals diminished a student’s probability of earning a degree. We conclude by discussing implications for practice, policy, and future research.
Successes and challenges of learning to support children post-COVID-19
Authors: Adams Megan , Rodriguez Sanjuana , Ramirez Karla , Garefino Allison , Jackson Virginie
Published: January 2025

This study investigated the experiences of faculty mentors and college students majoring in education or social work during a four-week summer program serving children in first and second grade. The college students worked as tutors, implementing an evidence-based reading program supported by training in mental health and behavior interventions. The case study design was used to determine impacts on the college students. Observations of college students, reflections from the college students, and vignettes from the faculty mentors were the data sources for the study. The key themes resulting are challenges working with children from socioeconomically and linguistically marginalized communities; successes and rewards of working with children; confidence as teachers; and mental health. The research indicates that further study is needed on embedding social work tenets into education programs on college campuses and mental health services are needed for all students K-20 post-COVID.
Passing the Baton
Authors: Guy Mary E. , Williams Brian N.
Published: January 2025

As our term as the inaugural editors-in-chief of this journal concludes, we trace the journal’s path and welcome the incoming editorial team. Created as a public administration journal focusing on all issues related to social equity, the range of topics covered is already vast and promises to grow. Articles published in the first two volumes range from racial healing to invisible disabilities, from Medicaid expansion to school resegregation, from white supremacy to the equity challenges that confront Tribal communities, from critical race theory to policing, from gender equity to equity in death, from retirement funds to equitable budgeting, from voting to UN Sustainable Development Goals (SDGs), and many more. JSEPA draws attention to the social equity pillar in public administration and joins the many journals dedicated to the other pillars of the field.
Purple Yam Flour (Dioscorea alata Linn.) Processing and Development of Instant Pudding Mix
Authors:   Industrial Technology Institute, HMT Herath
Published: January 2025

Purple yam (Dioscorea alata Linn.) is an untapped natural nutrient-rich source of food ingredient available in Sri Lanka. The present study aimed to transform purple yam into shelf-stable flour and to develop a Ready-To-Cook (RTC) pudding mix. The edible portion of D. alata yams was blanched, dried, powdered and sifted to process the yam flour.
Profit Analysis of Beef Cattle Business on Sinar Pagi Livestock Group, in Limapuluh Kota District, West Sumatra
Authors: Edwin Tevina , Arfa'i  , Rastosari Adisti , Utami Yolani
Published: January 2025

This study aims to determine the income and analyze the profit level of the beef cattle business owned by the Sinar Pagi livestock group in Limapuluh Kota Regency, Sumatera Barat Province. This research contributes to the wider debate on improving rural livelihoods and achieving sustainable agricultural development, and is essential for understanding the profitability of smallholder livestock enterprises. The results of this research will provide insights into the financial sustainability of their operations and will inform strategies for the optimisation of their business performance. The research was carried out using a case study method with 16 key informants, also members of the Sinar Pagi livestock group. Data were analyzed with descriptive quantitative methods. The study results show that the income earned by this livestock group in one year of research is IDR 6,471,775, with a profit rate of 1.08/year. It can be concluded that the Sinar Pagi livestock group only gets a profit of 8%, and this profit has not been able to meet the needs of the farmer's life.
Translating the Neck Pain Clinical Guidelines Into Practice: An Integrated Framework Approach
Authors: Ramirez Michelle M. , Carvalho Marissa , Clewley Derek , Pruka Katie , George Steven Z. , Horn Maggie E.
Published: January 2025

OBJECTIVE: To evaluate the implementation of the Academy of Orthopaedic Physical Therapy Neck Pain Clinical Practice Guidelines (CPGs) in a physical therapy department and assess adherence to evidence-based recommendations.

DESIGN: Prospective observational cohort study.

METHODS: The implementation strategy was guided by integration of the Donabedian Quality of Care Model and the Knowledge to Action Framework, incorporating a needs assessment, active training modules, self-audits, and electronic health record integration. Descriptive statistics characterized providers, compliance, and treatment adherence by impairment-based category. Chi-squared tests compared provider outcomes postimplementation.

RESULTS: Twenty physical therapists participated comprising 67 patients for a total of 132 patient visits. The mean difference in confidence ratings across CPG components was +5.41 points (95% confidence interval: 3.79, 7.03) on the visual analog scale; however, this was not statistically significant ( P>.05). Compliance with outcome measure collection and CPG-recommended evaluation components was 92% (186/202) and 77% (213/278), respectively. Adherence to recommended interventions varied between impairment-based category, ranging from 46% to 68%.

CONCLUSION: While providers were generally confident in applying the Neck Pain CPG, adherence in a clinical setting was suboptimal. The study underscores the importance of evaluating barriers and facilitators, tailored strategies, and refining implementation processes to improve guideline adherence and improve outcomes. JOSPT Open 2025;3(2):1-8. Epub 3 January 2025. doi:10.2519/josptopen.2025.0101
Transmetalation for DNA-based Molecular Electronics
Authors: De Arpan , Lu Brandon , Ohayon Yoel P. , Woloszyn Karol , Livernois William , Yang Chu-fan , Perren Lara , Mao Chengde , Botana Antia S. , Hihath Joshua , Canary James W. , Sha Ruojie , Anantram M.P. , Vecchioni Simon
Published: January 2025

The rational design of molecular electronics remains a grand challenge of materials science. DNA nanotechnology has offered unmatched control over molecular geometry, but direct electronic functionalization has been a challenge. We present here a generalized method for tuning the local band structure of DNA using transmetalation in metal- mediated base pairs (mmDNA). We develop a method for time-resolved X-ray diffraction using self-assembling DNA crystals to establish the exchange of Ag+ and Hg2+ in T:T base pairs driven by pH exchange. Transmetalation is tracked over six reaction phases as crystal pH is changed from pH 8.0 to 11.0, and vice versa. We then perform a detailed computational analysis of the electronic configuration and transmission in the ensuing crystal structures. Our findings reveal a high conductance contrast in the lowest unoccupied molecular orbitals (LUMO) as a result of metalation. The ability to exchange single transition metal ions as a result of environmental stimuli heralds a means of modulating the conductance of DNA-based molecular electronics. In this way, we establish both a theoretical and experimental basis by which mmDNA can be leveraged to build rewritable memory devices and nanoelectronics.
LEGOLAS: a Machine Learning method for rapid and accurate predictions of protein NMR chemical shifts.
Authors: Darrows Mikayla , Kodituwakku Dimuthu , Xue Jinze , Pickering Ignacio , Terrel Nicholas , Roitberg Adrian
Published: January 2025

This work introduces LEGOLAS, a fully open source TorchANI-based neural network model designed to predict NMR chemical shifts for protein backbone atoms. LEGOLAS has been designed to be fast, and without loss of accuracy, as our model is able to predict backbone chemical shifts with root-mean-square errors of 2.69 ppm for N, 0.95 ppm for Ca, 1.40 ppm for Cb, 1.06 ppm for C’, 0.52 ppm for amide protons, and 0.29 ppm for H. The program predicts chemical shifts at least one order of magnitude faster than the widely utilized SHIFTX2 model. This breakthrough allows us to predict NMR chemical shifts for a very large number of input structures, such as frames from a molecular dynamics trajectory. In our simulation of the protein BBL from E. coli, we observe that averaging the chemical shift predictions for a set of frames of an MD trajectory substantially improves the agreement with experiment with respect of using a single frame of the dynamics. We also show that LEGOLAS can be successfully applied to the problem of recognizing the native states of a protein among a set of decoys.
Estrategias didácticas para estimular la resolución de problemas matemáticos en estudiantes una institución educativa- Amazonas
Authors: Izquierdo Suarez Ermitanio
Published: January 2025

El objetivo de esta investigación fue identificar los efectos de las estrategias didácticas implementadas para fomentar la resolución de problemas matemáticos en los estudiantes de una institución educativa en el distrito de Bagua Grande, provincia de Utcubamba, Amazonas. A través de un enfoque cuantitativo, se llevó a cabo un estudio descriptivo y correlacional para evaluar la eficacia de dichas estrategias en el rendimiento académico de los estudiantes. La investigación se centró en el uso de metodologías activas y participativas, como el aprendizaje basado en problemas (ABP), que fueron diseñadas para mejorar la comprensión y aplicación de conceptos matemáticos complejos. Se utilizó un diseño de corte transversal y se trabajó con una muestra de estudiantes seleccionados de manera no probabilística, lo que permitió obtener resultados específicos sobre el impacto de las estrategias en el aprendizaje matemático. Los instrumentos utilizados para la recolección de datos fueron validados previamente, asegurando la fiabilidad y precisión de los resultados obtenidos. Los resultados mostraron un incremento significativo en el rendimiento de los estudiantes en la resolución de problemas matemáticos, evidenciando que las estrategias didácticas aplicadas tuvieron un impacto positivo en su capacidad para resolver problemas. En conclusión, la investigación resalta la importancia de implementar estrategias innovadoras que favorezcan el aprendizaje activo y mejoren las habilidades matemáticas de los estudiantes en contextos educativos diversos.
Auditoria de gestión y calidad educativa en la institución educativa Juan Velasco Alvarado, Cañaris, Ferreñafe
Authors: Ruiz Peralta Wilder , Ramos Saavedra Benjamín
Published: January 2025

El objetivo de esta investigación fue identificar la relación entre la auditoría de gestión y la calidad educativa en la Institución Educativa Juan Velasco Alvarado. El estudio se desarrolló bajo un enfoque cuantitativo, con un diseño de investigación básica de tipo descriptivo correlacional y un diseño transaccional o de corte transversal. La muestra consistió en 100 participantes, seleccionados mediante un muestreo no probabilístico intencional, basado en la conveniencia. Para la recopilación de datos, se empleó un instrumento de medición que garantizó una alta confiabilidad y validez de juicio, asegurando la calidad de los datos obtenidos. Los resultados mostraron una relación significativa entre la auditoría de gestión y la calidad educativa, lo que evidencia que una gestión adecuada de los recursos y procesos dentro de la institución influye de manera directa en los resultados educativos. La investigación destaca la relevancia de realizar una evaluación constante de la gestión administrativa y pedagógica para promover la mejora continua de los procesos educativos. A partir de los hallazgos, se concluye que la implementación de prácticas eficaces de auditoría de gestión puede jugar un papel crucial en el fortalecimiento de la calidad educativa, favoreciendo un entorno de aprendizaje más eficiente y alineado con las necesidades de los estudiantes.
Constructing Online Open Courses in Geriatric Nursing for Secondary Vocational Schools Using the OBE Framework
Authors: Han Xin , Li Yingying , Li Li , Li Liang
Published: January 2025

Based on the Outcome-Based Education (OBE) concept, the design of the secondary vocational online open course “Geriatric Nursing” plays a crucial role in enabling students to effectively acquire relevant knowledge and skills in geriatric nursing. First, an integrated design of learning outcomes should be established in line with the OBE framework, clearly outlining the competency levels students must achieve in geriatric nursing. Second, a structured curriculum must be developed to address the practical needs of geriatric nursing roles, ensuring course content aligns with real-world applications. Lastly, it is essential to implement a student-centered approach that combines online and offline teaching, prioritizing the learning experience and personalized needs of students. Adhering to the principles of “integrated design, structured curriculum, and blended teaching,” the development of the “Geriatric Nursing” online open course facilitates the transition from discipline-oriented to goal-oriented instruction and shifts the focus from teacher-centered to student-centered learning, ultimately advancing the training of geriatric nursing professionals.
Practical Insights from Case Studies of Community Medical and Nursing Integrated Services in Britain, the United States, and the Netherlands
Authors: Zhou Moyue , Fu Qi
Published: January 2025

The Chinese government has issued a series of policies to promote the development of community medical and nursing integrated services. Since the development of these services involves the transition of medical and health services from public spaces to private spaces, the home has become a critical factor in service provision. It is therefore essential to consider the concept of home and the sense of at-homeness in the research and practice of community medical and nursing integrated services in China to avoid prioritizing “others“ over “self-being.“ Through an analysis of three cases from Britain, the United States, and the Netherlands, this article demonstrates that a sense of control and social connection are key components of the elderly’s sense of at-homeness. Community medical and nursing integrated services should not only enable the elderly to maintain their sense of self-control but also assist in building a supportive social network.
Mechanistic Insights into Ginger’s Role in Improving Sperm Malformation Under Heat Stress Using Network Pharmacology and Molecular Docking
Authors: Xiao Rongrui , Li Huaqin , Huang Zheng , Yang Fang , Zhao Lijuan
Published: January 2025

Objective: This study investigates the effects of ginger on sperm dysmorphosis under heat stress using network pharmacology and molecular docking techniques. Methods: The core components, target sites, and primary pathways of ginger were predicted using the TCMSP database. Genes associated with sperm malformation and heat stress were identified through databases such as GeneCards and DisGeNET, followed by KEGG and GO analyses based on intersections with ginger targets. Core genes identified via Cytoscape software were subjected to molecular docking with ginger’s active components. Results: The principal active components of ginger identified include β-sitosterol and dihydrocapsaicin. Network pharmacology analysis suggested that ginger exerts its effects through pathways such as the prostate cancer signaling pathway, estrogen signaling pathway, inflammatory pathways, and nuclear receptor signal transduction. These pathways may ameliorate sperm malformation symptoms caused by heat stress. Conclusion: Integrating findings from network pharmacology and molecular docking, the active components of ginger potentially modulate the expression of heat shock proteins during heat stress via inflammatory and oxidative stress pathways. This modulation may protect spermatogenesis under heat stress and improve sperm malformation.
Nursing Care of a Patient with Active Crohn’s Disease Complicated with Small Intestinal Obstruction
Authors: Zhang Shaohua , Huang Yanchun
Published: January 2025

This study summarizes the nursing experience of a patient with active Crohn’s disease in the acute stage, complicated by small bowel obstruction. Key aspects of nursing include psychological response guidance during the active phase of Crohn’s disease, support before and after various gastroenteroscopy procedures and related reports, and self-monitoring guidance for symptoms such as intestinal obstruction combined with endoscopic mucosal ulcers. Using the 5A nursing model, nursing staff assessed the patient’s needs, provided targeted nursing recommendations in stages, implemented health behavior strategies, and offered continuous nursing care, including positive support for sexual health beliefs. These interventions helped the patient overcome psychological challenges, such as resistance to indwelling gastric tubes, and adopt healthy behaviors. After six weeks of follow-up through phone and WeChat consultations, the patient demonstrated significant improvement, including a weight gain of 15 kg. Various test results indicated normalized nutritional and inflammatory indexes, and the Crohn’s Disease Activity Index decreased by ≥ 70 points. In conclusion, establishing a nursing team and applying the 5A nursing model to formulate detailed nursing diagnoses and interventions can significantly improve outcomes for patients with active Crohn’s disease complicated by small intestinal obstruction.
Nursing Care of a Child with Panhypopituitarism After Craniopharyngioma
Authors: Feng Na , Lu Yan , Du Qingqing
Published: January 2025

This article summarizes a case of nursing management for a child diagnosed with craniopharyngioma. The targeted nursing interventions addressed panhypopituitarism, secondary hypothyroidism, secondary adrenal insufficiency, and central diabetes insipidus, which occurred as complications of the condition. The nursing priorities included the management of hypothyroidism, adrenal insufficiency, central diabetes insipidus, abnormal liver function, insulin resistance, and other related issues. The interventions resulted in stable hormone levels, maintenance of normal water and electrolyte balance, improved self-image perception, enhanced understanding of the disease and treatment plan by the child and their family, increased treatment compliance, and favorable therapeutic outcomes.
Summary of Chemical Constituents and Pharmacological Effects of Essential Oil of Sweet Orange from Southern Jiangxi Province
Authors: Zhang Jing , Liu Yuhao , Zong Wenjing
Published: January 2025

Gannan sweet orange essential oil has garnered significant attention due to its diverse chemical composition and pharmacological activities. The main active ingredients include sabinene, limonene, and linalool, which exhibit antioxidant, anti-inflammatory, antibacterial, and analgesic properties. This essential oil has potential applications in the development of medicinal products. This paper reviews the primary chemical composition and pharmacological effects of Jiangxi orange flower essential oil, highlighting the need for future research to focus on its biological activity and clinical application potential. Additionally, it emphasizes the importance of optimizing extraction and detection technologies to enhance its application value in medicine and other industries, thereby promoting the development of Gannan’s sweet orange industry.
Electrospinning - A Potential Bio-Fabrication Method for Developing Various Tissue Engineering Scaffolds
Authors: Shanmugam Kirubanandan , Dhanasekaran Ponnusamy , Santhosh Viswanathan
Published: January 2025

Scaffolds in tissue engineering provide essential support for new tissue growth. Such scaffolds could be fabricated from materials like natural and synthetic polymers with prime properties such as biocompatibility and mechanical strength. Among other developments made, electrospinning has been a significant factor in making intricate scaffolds that imitate the extracellular matrix of tissue. It gives various properties in the fibers for specific applications by the controlled parameter conditions like voltage and flow rate. It is innovations like multi-component fibers and 3D structures that assist in the problem of uniformity and mechanical strength. Electrospinning research still is on the front line in increasing its potential applications in tissue engineering, filtration, and drug delivery. Process parameters optimization is among the strategies deployed to lessen the electrospinning problem of bending instabilities. The modified setups offer fiber production versatility. The setups introduced include far-field electrospinning that provides long, directed nanofibers and near-field electrospinning that gives good fiber deposition. Electromechanical spinning unifies electrical and mechanical aspects to have controlled fiber properties. In the area of applications of electrospun nanofibers, so far, the areas like biomedical, environmental, energy, textile, sensor, agriculture, cosmetic, and food packaging industries come as a real versatile bunch. This potential of the technology in divergent fields is ever-growing, in ongoing research continues to enhance its effectiveness toward tissue engineering solutions.
FLCN - A Promising Novel Prognostic Biomarker for Lung Adenocarcinoma (LUAD) Patients
Authors: Abid Muhammad Umair , Hameed Yasir
Published: January 2025

Rationale: The tumor suppressor FLCN gene mutations are the primary cause of the rare autosomal recessive genetic disorder known as Birt-Hogg-Dubé (BHD) syndrome. Early diagnosis of BHD is difficult since FLCN mutation-caused tumors can form in the skin, lungs, kidney, and other organs and are benign. These tumors generate a range of phenotypes. Methods: The UALCAN database was utilized to ascertain FLCN expression and methylation in LUAD. Additionally, using KM plotter, GEPIA2.0, and cBioPortal, respectively, the survival, validity, and mutation analysis of FLCN was ascertained in LUAD. Using STRING and DAVID tools, the pathway and gene enrichment were identified in the presence of FLCN. The muTarget database was used to identify the mutant genes. Results: The goal of the current study is to examine FLCN expression in LUAD tissues. In these patients with LUAD, the study compared the expression of FLCN to other clinic-pathological characteristics. When comparing LUAD patients’ clinical parameters to those of normal control samples, FLCN expression was higher. Additionally, it was discovered that a higher expression of FLCN in LUAD patients was linked to a shorter overall and disease-free survival. Results of gene ontology and pathway analysis demonstrated that genes linked with FLCN are significantly co-expressed with FLCN and are involved in a wide range of distinct molecular functions, biological processes, and pathways. FLCN expression was also correlated with promoter methylation levels, genetic alterations, other mutant genes. This crucial information demonstrated the important function that FLCN plays in the initiation and expansion of LUAD. Conclusion: This research emphasizes how crucial genetic analysis is to the diagnosis and the therapeutic treatment of LUAD.
The Impact of Narrative Nursing on Body Image, Disability Acceptance, and Psychological Hope Level in Young and Middle-aged Breast Cancer Patients After Surgery
Authors: Huang Sisi , Yan Mei , Li Yuhua , Yang Xiumei , Zhou Jie , Yang Ting , Li Shasha
Published: January 2025

Objective: To investigate the effects of narrative nursing on body image, disability acceptance and psychological hope level of young and middle-aged breast cancer patients after radical surgery. Methods: A non-randomized quasi-experimental study was used to divide 80 patients in the Department of Breast Surgery of a tertiary cancer hospital in Yunnan Province from October 2023 to September 2024 as the study subjects and the study subjects were divided into the intervention group and control group with 40 cases in each group. The intervention was performed within 1 month after surgery, and a total of 5 interventions were performed. The two groups of patients were evaluated by the breast cancer patients’ body image self-rating questionnaire, the revised version of the Disability Acceptance Scale, and the Herth Hope Assessment Scale. Results: There were no significant differences in BISQ-BC, ADS-R, and HHI between the intervention group and the control group before intervention (P > 0.05). After the intervention, the BISQ-BC score of the intervention group was lower than that of the control group, and the ADS-R score and HHI score were higher than those of the control group, and the difference was statistically significant (P < 0.05). Conclusion: Narrative nursing can effectively improve the physical image level of young and middle-aged breast cancer patients, improve the disability acceptance and psychological hope level of young and middle-aged breast cancer patients, and help them vent their negative emotions, gain confidence in life, and improve their quality of life.
Case Report: B-cell Acute Lymphoblastic Leukemia/Lymphoma Following Castleman Disease
Authors: Zhao Meng , Li Qirui , Jiang Tao , Xu Dafei , Ma Qian , Tao Lunfei , Miao Ziwei
Published: January 2025

Castleman disease (CD) is a rare nonmalignant lymphoproliferative disorder presenting systemic symptoms such as fever, night sweats, fatigue, anemia, effusions, and multifocal lymphadenopathy. The etiology of CD has not been clarified to date. The coexistence of CD with B-cell acute lymphoblastic leukemia/lymphoma (B-ALL/LBL) has been rarely reported. Although the pathogenesis remains unclear, this association probably reflects an incidental and fortuitous finding rather than the alteration of a common pluripotent stem cell precursor. Herein, the study reports on one case of CD coexisting with B-ALL/LBL and elucidates the underlying mechanism of pathology in some aspects.
Exploring the individual experiences of women facing cervical cancer: a study on sexual life changes, emotional responses, and physical adaptations
Authors: Kurniasih Dwi , Goretik Maria , Siskawati Siskawati
Published: January 2025

Background: Cervical cancer is one of the significant cancers in the female reproductive organs, namely the cervix. Diagnosis and treatment of cervical cancer not only affect physical health, but also psychologically and socially, especially in the context of sexual life. Physical and emotional changes that arise from treatments such as chemotherapy and radiotherapy can significantly affect women's sexual function, cause anxiety, and change the dynamics of interpersonal relationships.
Subjects and Method: This study uses a qualitative approach with a descriptive phenomenological design. Data collection was conducted through in-depth interviews with five cervical cancer patients undergoing treatment at the Dr. Soedarso General Hospital, Pontianak. Data were analyzed using a thematic analysis approach to identify key themes in the experiences of changes in sexual life, emotional responses, and physical adaptation of the participants.
Results: The results of the study showed that cervical cancer patients experienced various changes in their sexual lives after undergoing treatment. The main challenges faced were physical discomfort that leads to difficulty in achieving sexual satisfaction, diversion of sexual activities to meet the needs of partners, and complex emotional responses such as anxiety, depression, and feelings of hopelessness. Physically, adaptation to changes such as persistent fatigue and digestive changes were also significant problems.
Conclusion: This study highlights the importance of comprehensive psychosocial support in caring for women with cervical cancer, including a holistic approach that considers physical, emotional, and interpersonal aspects. The findings also highlight the need for better sexual health education for patients and their partners, as well as the important role of families in providing adequate support. By better understanding the experiences of women with cervical cancer, it is hoped that their care and overall quality of life can be improved.
Implementasi QR Code Untuk Sistem Informasi Pemesanan Menu Pada Restoran Omah Gedhe Pandean Kaliwungu Berbasis Web
Authors: Rusito Rusito , Diyah Intan Mawarni Putri
Published: January 2025

Penelitian ini bertujuan untuk mengembangkan dan mengimplementasikan sistem informasi pemesanan menu berbasis web dengan menggunakan QR Code pada Restoran Omah Gedhe Pandean Kaliwungu. Sistem ini dirancang untuk meningkatkan efisiensi dan kenyamanan dalam proses pemesanan makanan di restoran. QR Code digunakan sebagai media untuk mengakses menu digital, yang memungkinkan pelanggan untuk memindai kode dengan perangkat seluler mereka dan langsung melihat daftar menu serta melakukan pemesanan tanpa harus menunggu pelayan. Hasil dari implementasi ini menunjukkan bahwa sistem informasi berbasis QR Code ini mampu meningkatkan kecepatan pelayanan, mengurangi kesalahan pemesanan, dan memberikan pengalaman yang lebih interaktif bagi pelanggan. Penelitian ini menggunakan metode R & D (Research andDevelopment) Brog & Gall yang merupakan suatu metode penelitian yang digunakan untuk menghasilkan produk tertentu dan menguji produk tertentu. Penelitian ini  hanya menggunakan 6 langkah dari 10 langkah. Hasil validasi dari pakar dan user nilai rata – rata validasi dari 2 responden menunjukan 31,5, nilai tersebut berada pada rentang 31-40, dapat disimpulkan bahwa rancangan sistem ini “Sangat Valid”.