bluuebunny/crossref_metadata_2025 huggingface dataset:
Developing and validating a nomogram for prediction coronary heart disease in patients with chronic obstructive pulmonary disease
Authors: Yu Yun , Cai Xiao-Xian , Chen Jun-Lin , Xu Jing-song
Published: March 2021

Background

Previous studies indicate that there is an association between chronic obstructive pulmonary disease (COPD) and coronary heart disease (CHD). Herein,we established and further validated a novel nomogram for predicting CHD in patients with COPD.
Methods

In total,we assessed 421 patients with COPD admitted in the Second Affiliated Hospital of Nanchang University between January 2017 to August 2019 .Univariate and multivariate analyses were used to develop a nomogram model containing variables which we screened,testing the discriminative ability and calibration of the nomogram by C-index,area under the curve(AUC) and calibration plots. Decision curve analysis was applied to evaluate the benefit of the screeing model.Further, we conducted an internal validation by using the bootstrapping validation.
Results

Multivariate analysis shows that arterial thrombosis,prealbumin,albumin and estimated glomerular filtration rate are independent factors in predicting the risk of CHD.The prediction model exhibited discriminative ability with a C-index of 0.882 (95% CI: 0.848–0.916), and the AUC at 0.878(95% CI: 0.843–0.913).The nomogram demonstrated efficient calibration and clinical applicability when deciding on interventions with a CHD possibility threshold of 7% .During the interval validation, it could still attain a C-index value of 0.869.
Conclusion

The nomogram can predict the risk of CHD in patients with COPD,with a high discriminative ability and potential clinical applicability.
Interaction between CETP Polymorphism and Dietary Insulin Index and Load on Cardiovascular Risk Factors: A Cross-Sectional Study of Diabetic adults
Authors: Abaj Faezeh , Rafiee Masoumeh , Koohdani Fariba
Published: March 2021

Background
The objectives were to investigate the effect of the interaction between CETP Taq1B polymorphism, Dietary Insulin Index and Insulin Load (DII and DIL) on cardiovascular risk factors among diabetic patients.
Methods
In this cross-sectional study, blood samples were collected from 220 patients. DIL and DII were obtained via validated FFQ. CETP Taq1B polymorphism was genotyped by the PCR-RFLP method.
Results
The highest BMI (P = 0.08) and WC (P = 0.01) values were observed in B2B2 genotype with the highest adherence to DII. Patients with B1B1 genotype who were in the highest DIL tertile had lower LDL/HDL (P = 0.001), TG (P = 0.03), and higher HDL (P = 0.02). The highest SOD (P = 0.01), PGF2α (P = 0.04), CRP (P = 0.02), and IL-18 (P = 0.06) was observed in B2B2 genotype carriers with the highest DIL adherence. Individuals with B2B2 genotype in the highest tertile of DII had higher CRP (P = 0.04), TAC (P = 0.01), SOD (P = 0.02), and PGF2α (P = 0.02). B1B1 homozygotes who were in the highest tertile of DII had lower lipid profile TG (P = 0.02), LDL (P = 0.08), and LDL/HDL < 0.001.
Conclusion
Based on the current study, it may be proposed that CETP Taq1B polymorphism can be associated with CVD risk factors in diabetic patients with high adherence to insulin indices, including DII and DIL
Optimal Timing of Introduction of Complementary feeding: Protocol for a systematic review and meta-analysis
Authors: Padhani Zahra A. , Salam Rehana A. , Lassi Zohra S. , Siddiqui Faareha , Keats Emily C. , Das Jai K , Black Robert E , Bhutta Zulfiqar A
Published: March 2021

Background: The complementary feeding (CF) period accompanies a critical window of vulnerability. During this time, failure to consume adequate energy, protein, vitamins and minerals is a significant concern and can lead to poor growth outcomes, increased susceptibility to infections, allergies, and diseases, and lower developmental potential. It is therefore of utmost importance to determine the most optimal time to start CF. The objective of this review is to assess the impact of early and late of introduction of CF on infant health, nutrition and developmental outcomes.Methods: We will follow the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. We will search MEDLINE, Embase, CINAHL, CENTRAL, Web of Science, and other databases and key organizational websites using terms related to complementary feeding and infants. We will also search clinicaltrials.gov for ongoing trials. We will include experimental (randomized trials (individually or cluster) and quasi-randomized trials) and observational studies with a concurrent comparison group (cohort (prospective and retrospective), controlled before-after studies and nested case control studies). We will only include studies that enroll infants, living in low, middle- or high-income countries. Outcomes will be assessed for the following two comparisons:1. Early introduction of CF (before 5 months of age) compared to introduction at 5 to 6.9 months of age2. Late introduction of CF (after 7 months) compared to introduction at 5 to 6.9 months of age All the included studies will be screened on Covidence software and analyzed on Review Manager (version 5.4.1) software.Discussion: There are inconsistencies in the existing recommendations for the introduction of CF, as the recommended age for introducing CF ranges between four and six months of age in various international guidelines. It is imperative to evaluate of consequences of both early and late introduction of complementary foods since optimal timing of introduction may have potential beneficial short- and long-term health effects. Systematic review registration: PROSPERO CRD42020218517
Factors for crowding in the early mixed dentition stage
Authors: Sharma Karuna , Kohli Anil , Katiyar Ashish , Panda Sujit , Katyayan Rahul
Published: March 2021

Objective:  To  find  out  the  factors  responsible  for  crowding  in  the  early  mixed  dentition. 

Materials  and  methods:  60  dental  casts  of  children  in  their  early  mixed  dentition  (  30  boys  and  30  girls)  were  divided  into  crowded  and  noncrowded  groups.  Comparison  were  made  between  the  two  groups  according  to  following  criterion:  -(1) space  available  for  permanent  lower  incisors, (2) total  incisor  width, (3) deciduous  intermolar  width, (5) permanent  intermolar  width, (6) interalveolar  width, (7) total  arch  length.  Correlation  of  the  measurements  with  crowding  was  also  evaluated. 

Statistical  analysis  used: Data  was  analysed  using  STATA-12.0  (STATA  SE,  StataCorp., Texas,  USA).  Means,  standard  deviation,  and  medians  were  calculated  for  describing  the data.  Data  was   tested  for  normality  using  Shapiro-Wilks  test.  Since  all  variables  were found  to  be  non-normally  distributed,  therefore  comparison  of  all  measurements  between the  crowded  and  non-crowded  groups  was  done  using  Wilcoxon  ranksum  test  (Mann-Whitney test).  All  values  were  considered  statistically  significant  for  a  value  of  p<0.05.

Results:  Mandibular  deciduous  intercanine  width  was  significantly  larger  in  Noncrowded  Group.  The  space  available  for  the  mandibular  permanent  incisors  and  total  arch  length  were  significantly  larger  in  Noncrowded  Group.  The  correlation  analysis  indicated  significant  correlations  between  crowding  and  available  space,  intercanine  width,  intermolar  width  I.  No  significant  correlation  was  found  between  crowding  and  intermolar  width  II,  permanent  intermolar  width,  and  interalveolar  width. 

Conclusion:  Procedures  which  preserve  the  arch  length  such  as  timely  restoration  of  proximal  caries,  prevention  of  premature  loss  of  deciduous  teeth  and  use  of  space  maintainers  such  as  lingual  arch  may  prove  useful  in  alleviating  crowding.
A split mouth clinical study to compare Subepithelial connective tissue graft and Guided tissue regeneration in the treatment of Miller’s class I and II gingival recession.
Authors: Garg Kamal , Naidu D V G , Gupta Udayan , Garg Yogesh
Published: March 2021

ABSTRACT

Background: Gingival recession (GR) can result in hypersensitivity, esthetic concern to the patient, and chances for root caries. The purpose of this randomized clinical study was to evaluate the effect of guided tissue regeneration (GTR) procedure using a bioabsorbable collagen membrane in comparison to autogenous Subepithelial connective tissue graft (SCTG) for root coverage in Miller’s class I and II gingival recession defects.

Materials and methods: In this split mouth study, 10 patients with 20 contralateral Miller’s class I or II recession defects were randomly treated with coronally advanced flap using either Subepithelial connective tissue graft (control group)  or resorbable collagen membrane (experimental group). The clinical evaluations were done using plaque index, gingival index, height of gingival recession, probing sulcus depth and clinical attachment level at baseline, 3 and 6 months post- operatively.

Results: Data analysis was done using descriptive statistics and student’s t test was used for comparisons. P value <0.01 was considered to be significant. Both the groups showed complete resolution of the defects at 6 months post operatively. Inter group comparison between both the groups at 6 months showed no statistically significant differences in any of the clinical parameters.

Conclusion:  Predictable outcome were observed in both the groups and indicated that collagen based guided tissue regeneration membrane i.e. ProGide can be safely used.
Comparison of the microleakage between two different flowable composite resin restorations with 8th generation bond system in Class II cavity: An in vitro stereomicroscopic study.
Authors: Singh Kaushal , Garg Amit , Singhal Rajnish K , Jain Anurag , Agarawal Neha , Pathak Vivek Kumar
Published: March 2021

Introduction Marginal adaptability of composite resins is one of the prime factors for the success of class II cavity restoration. Materials and Methodology: Forty non-carious extracted mandibular molar with fully formed apices were collected and Class II box type cavities were prepared on both mesial and distal surfaces of every tooth using a new straight fissure diamond bur and high-speed airrotor handpiece. According to the type of restorative materials used, teeth were divided into Group I (n=20): Restored with SDR (Smart Dentin Replacement) and Group II (n=20): Restored with Tetric Eva Flow Bulk Fill. After 24 hours of storage in distilled water at 37˚C, the restored specimens were subjected to artificial aging by thermocycling. The teeth were then immersed in a 2% methylene blue dye for 24 hours. All samples were cut longitudinally through the center of the restorations with the help of an isomet diamond saw. The sections were then observed under a stereomicroscope at 25X for scoring the depth of dye penetration at cervical and axial walls toward the pulp. Results: Mean score of Group Ia is 0.4±0.83 and Ib was 0.55±0.88 respectively while the mean score of Group IIa was 0.75±1.118 and in IIb was 0.75±1.019 respectively. Microleakage was found to be highest in Group IIa and minimum in Group Ia. Conclusion: Use of a flowable composite SDR above and below the CEJ in Class II composite resin restorations showed good results.
The results of divergence of early-maturing maize source material in heterosis breeding
Authors: В. Ю. Черчель  , Ю. Ю. Купар  , М. М. Таганцова  , О. Ф. Стасів
Published: March 2021

Purpose. To analyze the divergence of early maturing source material of corn Zea mays L. in heterosis breeding for the genetic base formation at the State Institution the Institute of Grain Crops of the NAAS of Ukraine.Methods. Field (comprehensive assessment of morphobiological and economically valuable characteristics of the source material and maize hybrids) individual selection, cumulative and recurrent selection, backross and testcrosses bree­ding methods; laboratory; analysis and synthesis; statistical.Results. The results of research on the analysis of the divergence of early maturing corn source material in the conditions of the Steppe of Ukraine has become a developed harmonized working collection of corn breeding samples adapted to the stressful conditions of this region. The gradual cyclical improvement of the lines made it possible to form the core of the genetic diversity of FAO 150–290 early maturing specimens of the southern ecotype, which are competitive in heterosis breeding. The complexity of breeding for early maturity in the steppe conditions is due to the lack of material adapted to the stress factors of the South of Ukraine. The available early maturing lines of the world collection F2, F7, Ер1, Ма21, Ма23, Со125, Со255, См7, PLS61, S72, etc., were distinguished by high cold resistance, good starting plant development, intensive accumulation of dry matter during ripening, but not adapted to the deficiency of moisture in the soil and high summer temperatures. According to the results of the experiment, it was revealed that, in terms of breeding, lines of Lancaster plasma (DK427 and DK633) were the most plastic, due to which a number of new mid-early lines were obtained, for example DK2/427, DK267, DK266/417, DK633/266, DK296, etc., which were included in the registered hybrids. Formation of the genetic base of early maturing maize source material for heterosis breeding and systematization accor­ding to different breeding characteristics provided a balance of samples of alternative components, which will be further used to model heterosis hybrids in the early maturing group.Conclusions. The updated basic collection of lines is represented by the samples of plasma Iodent: DK744SVZM, DK216SVZM, DK4173SVZM, DK235zS, DK257zM, SV, DK365SVZM, DK777ZMSV, DK733-7zM,SV, DK315SVZM; Lancaster: DK296zS,VM, DK633/266zS,VM, DK2965ZSZM, DK2953 ZSZM, DK3023 ZSZM, DK236zS,ZM; Raid (SSS): DK232MV, DK2323MV, DK239MV; Mixed: DK253ZSZM, DK273MV, DK272zS, DK281SV, DK233zM,SV, DK959MV, DK9527 ZSZM, DK247MV, DK2442MV, which is the basis of the genetic diversity of early ripening corn samples included in the State register of plant varie­ties suitable for dissemination in Ukraine.
ANÁLISE DOS CONFLITOS POR ÁGUA NO ESPAÇO AGRÁRIO PARAENSE (2013-2016)
Authors: Almeida Gusmão Luiz Henrique , Sombra Daniel , Vale Costa Francisco Émerson
Published: March 2021

A gestão das águas é bastante complexa no espaço brasileiro e se torna ainda mais onde esse recurso é abundante, como é o caso da Amazônia brasileira, onde há grande capacidade de geração de energia e grandes empreendimentos sendo realizados. Esse contexto espacial se converte em uma seara de conflitos entre comunidades rurais e agentes atuantes no espaço agrário paraense em particular. Esse artigo privilegia os conflitos por água no espaço agrário paraense. O propósito deste estudo é avaliar a distribuição dos conflitos e da quantidade de famílias envolvidas em confrontos por causa da água nos municípios paraenses. Para validação dos resultados da pesquisa foram utilizados dados da Comissão Pastoral da Terra (CPT) no período entre 2013 e 2016, e através destes foram confeccionados mapas temáticos com o fim de analisar minuciosamente essa situação. A partir dos resultados, constatou-se que as regiões de integração do Xingu e do Tapajós concentram a maioria dos conflitos e das famílias afetadas no espaço agrário por conflitos de água, especialmente em decorrência de usinas hidrelétricas em processo de operação. Segundamente, há destaque para os conflitos por água derivados da atividade da mineração e do agronegócio. Os resultados apontam para a necessidade de uma política de gestão dos recursos hídricos própria a um contexto de abundância de águas.
Medication Regimen Complexity and Medication Adherence In Patients with Polypharmacy
Authors: GnanaSwarupin Ms.K. , Prabha G.RamyaBala , Santhosha Dharmapuram , Hepciba Nadimidoddi
Published: March 2021

The complexity of medication regimen can be defined by the number of medications (polypharmacy) and the number of times per day or dose. The term medication adherence is defined by WHO as the extent to which a perosn’s behavior agrees with the agreed medication regimen from a healthcare provider. . The main objective of the study is to implement medication regimen complexity index in patients with polypharmacy and to evaluate the rate of medication adherence in polypharmacy patients and also the factors affecting for non adherence Hospital based prospective case study was conducted for a period of 8 months after obtaining permission from Institutional Ethical Committee, CMR College of Pharmacy, Hyderabad. Data was collected and analysed according to inclusion and exclusion criteria. A total of 165 cases were included and analyzed for the study and was found that the most common age group with polypharmacy was between 51-60 years with male predominance. Study observation reveals that most of the uneducated patients are non adherent to their medication. The low complexity MRCI score included tracks between 6.0 to 13.0, while the high complexity MRCI score included tracks of 13.0 to 22.5. Most of the elderly patients were found to have high complexity. Among 165 patients, 98 were non-adherent and 67 were adherent to treatment regimen. i.e, most of the patients were non adherent to medications. Present study concludes that elderly patients were present with higher regimen complexity than adults and older adults. Most of the polypharmacy patients were found to have high regimen complexity with score of 15. Most of the patients were found to be non adherent to the therapy in polypharmacy patients.
Evaluation of Wound Healing Activity of Catharanthus Roseus Aqueous Extract in Adult Albino Rats
Authors: Satish A M , M. K Jayanthi , Gangadhar Totagi Vinod , Ramu Ramith
Published: March 2021

Use of plant extracts in the treatment of several ailments is a science known to the mankind since time immemorial. Yet, its popularity is limited owing to the lack of recorded experimental evidence to determine their potential health benefits. C. roseus is a traditional medicinal plant with over 100 identified alkaloids and several other phytochemicals known for various health promoting activities. The aim of the present study was to evaluate C. roseus aqueous extracts’ wound healing potential using incision, excision, and dead space wound models on healthy male albino rats. To assess this, the tissue breaking strength for incision wound model, percent epithelialization and period to complete epithelialization for excision wound model and granuloma break strength, dry weight, and hydroxyproline content for dead space wound model were evaluated after the treatment of the extract in comparison with the standard drug sucralfate. The results obtained demonstrated that the treatment of extract on the wound significantly enhanced tissue breaking strength and reduced the time required for complete epithelialization and was on par with that of the standard drug sucralfate. In the incision wound model, an elevated breaking strength was observed compared to that of the control group. Further, in the dead space wound model, the granuloma dry weight and breaking strength were remarkably elevated along with a concomitant increase in the hydroxyproline content suggesting the enhanced rate of wound contraction rate, collagen synthesis and lowered healing period. In conclusion, the present study demonstrates that C. roseus is effective in wound healing, as shown in the three wound models and thus, further studies to formulate this into a commercial product should be carried out.
HOW PARENTS EDUCATION IMPROVE STUDENT ACHIEVEMENT?
Authors: Kurniaman Otang , Indarni Annisa , Noviana Eddy
Published: March 2021

The Education in elementary school is a very important factor. Because the elementary school level is the foundation for the development of children's thinking and learning abilities influences and influences to the next level. The purpose of this research is to determine the academic achievement of students who are influenced by the parent’s education level. This research used a quantitative approach with a correlation test. The research conducted at Elementary school of 105 Tampan Pekanbaru to all of grade V students, with 150 total students. The Researcher used the Krejcie and Morgan tables sampling with 108 students. Based on the results of the correlation test shows that the magnitude of the father's education correlation coefficient on student academic achievement is 0.012 while the correlation of maternal education to student academic achievement is 0.081. Both are below the value of the r product moment correlation coefficient table for a sample of 108 with a significance level of 5% that is equal to 0.187. Thus the hypothesis H0 is accepted, it means that there is no meaningful relationship between parental education and student achievement.
ANALYSIS OF NEED FOR DEVELOPMENT OF HOTS-BASED MATHEMATICS TEACHING MATERIAL IN ELEMENTARY SCHOOLS
Authors: Nurlaily Vivi Astuti , Sholihah Husna Imro’athush
Published: March 2021

One of the 2013 curriculum transformation elements in elementary schools is strengthening the learning process and familiarizing the development of higher-order thinking skills (HOTS) for students.  This needs to be supported by teaching materials to support HOTS-based learning.This research aims to analyze the need for HOTS-based mathematics teaching materials in elementary schools. This research uses a descriptive approach. The subjects of this research were fourth-grade students of public elentary school in Tunjungan Blora area. The data collected in this research uses observation sheets, interviews, and document studies. Observations and interviews were carried out to teachers and fourth-grade students. Otherwise, the document studies were carried out on learning resources used in mathematics learning. The validity test data was conducted by using triangulation techniques. The results showed that:  first, the characteristics of mathematics teaching materials used in elementary schools of Blora Regency have not described the HOTS material. Second, the need for teachers shows that the problems faced by teachers in learning mathematics have limited learning resources. Third, the student's need toward teaching material products is shown by the low interest of students in learning mathematics. Fourth, students have not been invited to think critically in learning mathematics.
Peningkatan Stabilitas Lereng pada Ruas Jalan Tawaeli – Toboli dengan Vegetasi/Bioengineering
Authors: Wandira S.A. , Rahayu A.
Published: March 2021

Tawaeli - Toboli is one of the road that often undergo landslide. Most of these roads are in a mountainous area with high steep slopes and poor soil conditions. The road conditions worsened, especially in rainy season resulting the citizen do not know anywhere that is prone to landslides such as in Km 16 to 17. The purpose of this study was to analyze slope stability using bioengineering methods, determine the shear strength of soil without plant roots and soil with plant roots and to determine the potential for landslides that will occur. Bioengineering is used to increase the strength of the soil, and stabilize slopes and reduce erosion on slopes. The slope stability calculation using the Bishop slice method. The calculating of safety factor analyzed using the Slope / W application and manually. Soil samples were taken from 3 (three) points and the soil strength parameters,  soil cohesion and friction angle, were obtained through laboratory testing. Tests were carried out using rootless and rooted soil samples. In addition, direct field observations were made to obtain slope angles and slope heights. The results showed that the parameters of soil shear strength, cohesion and friction angle increased with the presence of plant roots. The results of the slope stability analysis show that the conditions of the slope are stable at slope 1 (Km 16) and slope 3 (Km 17) with a safety factor greater than 1.5. While slope 2 (Km 16 +300) has the potential for landslides as a safety factor of less than 1.5. The use of bioengineering increases the safety factor to be greater than 1.5. The calculation of the value of the safety factor using the Slope / W program and the Bishop manual is not much different, but the calculation time with the Slope / W program is faster
Asesment Bangunan Gedung di Universitas Tadulako Palu pasca Gempa 28 September 2018 untuk Pelaksanaan Rehabilitasi dan Rekonstruksi
Authors: Sulendra I.K.
Published: March 2021

After September 28 2018 Palu strong shock (7,5 Mw) caused damages of buildings, not exceptly on Tadulako University in Palu City. Those secondary impact of earthquakes i.e: lighweight, moderate, heavy damages until collaps of buildings. Therefore those impact caused activity proccess in this campus delayed. After shock caused damages many building, assessment of those buildings are necessary. Output of assessment needed for rehabilitation and reconstruction stages. The characteristics and types of damages very important to knew to next stages i.e: built back better post of earthquake disaster. Generally methods of assessment buildings after shock i.e : Rapid Visual Screening (RPS), Semi Destructive and Rapis Analysis and Detailing Analysis include Review Design with Up to Date Standard Design.  This assessment used “Quick Assessment for Non Engineered Structures” from Directorat General of Building PUPR for simple building (only one story building) and Level-1 Assessment Methods from World Bank for  Engineered Structures. Those assessment verification of : 140 unit building , 69 unit and 19 unit of lighweight, moderate ang heavy damages until failure respectively. Two years after the disaster, rehabilitation and reconstruction process i.e: 160 unit of non engineered building with lightweight-moderate damage has been repaired. Then on going process build of 10 muliperpuse steel frame of two stories building, with 12 class room each buildings. For engineered building with moderate damage category, this year until next year to retroffiting of structurals elemens, this retrofit to do for anticipate the next damage earthquakes. The rehabilitation and reconstruction process until 2023 for completly build after Palu Earthquakes. Next year until 2023 priority rehabilitation and rehabilitation for retroffiting main engineered structures building i.e: rektorat, auditorium, hospital, laboratory and rechange collaping building after diasaster.
Oxidant and Antioxidant Balance in Patients with COVID-19
Authors: Aykac Kubra , ozsurekci yasemin , Yayla Burcu Ceylan Cura , Gurlevik Sibel Lacinel , Oygar Pembe Derin , Boduc Nuriye , Tasar Medine , Erdinc Fatma , Ertem Gunay , Neselioglu Salim , Erel Ozcan , Cengiz Ali Bülent , Ceyhan Mehmet
Published: March 2021

Background: A crucial balance exists between oxidant and antioxidant
mechanisms in the functional immune system. We aimed to evaluate the
contributions of balance between these systems to coronavirus disease
2019 (COVID-19), a devastating pandemic caused by viral infection.
Method: We analyzed serum oxidant and antioxidant stress parameters
according to the clinical and demographic characteristics of children
and adults with COVID-19 and compared them against the values of healthy
controls. Serum native thiol (NT), total thiol (TT), disulfide, total
antioxidant status, total oxidant status, and ischemia-modified albumin
levels were evaluated and compared between groups. Results: A total of
79 children and 74 adults were evaluated in the present study, including
46 children and 40 adults with COVID-19, 33 healthy children, and 34
healthy adults. TT, NT, and disulfide levels were significantly lower in
the adult COVID-19 group than in all other groups (p = 0.001, p = 0.001,
and p = 0.005, respectively). Additionally, TT and NT levels were
significantly lower in both pediatric and adult COVID-19 cases with
severe disease course than mild/moderate course. TT and NT levels were
identified as predictors for the diagnosis of the adult COVID-19 cases
and as independent predictors for disease severity in both children and
adults with COVID-19. Conclusion: Parameters that reveal the oxidant and
antioxidant capacity, including TT and NT, appear to be good candidates
for the accurate prediction of the clinical course among patients with
COVID-19.
Environmental association modelling with loci under divergent selection predicts the distribution range of a lizard
Authors: Llanos-Garrido Alejandro , Briega-Álvarez Andrea , Pérez-Tris Javier , Díaz José
Published: March 2021

During geographical expansion of a species individual colonizers have to
confront different ecological challenges, and the capacity of the
species to broaden its range may depend on the total amount of adaptive
genetic variation supplied by evolution. We set out to test whether the
distribution of loci under selection along a contrasting environmental
gradient can be turned into a model that accurately predicts a species’
range. If positive, this may shed light on the genetic source of
adaptive limits that shape range boundaries. We sampled five populations
of the western Mediterranean lizard Psammodromus algirus that inhabit a
noticeable environmental gradient of temperature and precipitation. We
used 21 SNPs putatively under selection to correlate the genotypes of 95
individuals with environmental variation among their populations, using
1x1 km2 grid cells as sampling units. By extrapolating the resulting
model to all possible combinations of alleles, we inferred the locations
that were theoretically suitable for the species. The inferred
distribution range overlapped to a large extent with the realized range
of the species, including an accurate prediction of internal gaps and
range borders. Our results suggest an adaptability threshold determined
by the amount of genetic variation available that would be required to
warrant adaptation beyond a certain limit of environmental variation.
These results support the idea that the expansion of a species’ range
may be ultimately linked to the arising of new variants under selection.
Prognostic factors of hospital mortality for unplanned re-exploration after cardiovascular surgery
Authors: Deng Jianying , Zhong Qianjin
Published: March 2021

Objective To explore the prognostic factors of hospital mortality for
unplanned re-exploration after cardiovascular surgery. Methods We
retrospectively analyzed the data of 100 patients who underwent
unplanned re-exploration after cardiovascular surgery in our hospital
between May 2010 and May 2020. There were 77 males and 23 females, aged
(55.1±15.2) years. Demographic characteristics, operation information,
perioperative complications were collected to set up a database. The
patients were divided into survival group and non-survival group
according to hospital mortality. Logistic regression was used for
multivariable analysis to explore the prognostic factors of hospital
mortality. These statistically significant indicators were selected for
drawing the receiver operating characteristic curve of the evaluation
model, calculating the area under the curve(AUC) and evaluating the
effectiveness of the new model with Hosmer-Lemeshow C-statistic. Results
Hospital mortality was 26.0% (26/100). Multivariate logistics
regression revealed that the operation time of unplanned re-exploration,
the worst blood creatinine within 48h before the re-exploration, the
worst lactate within 24h after the re-exploration, cardiac
insufficiency, respiratory insufficiency, and acute kidney injury were
independent prognostic factors (p<0.05). The AUC of the new
assessment model constituted by these prognostic factors was 0.910, and
the Hosmer-Lemeshow C-statistic was 4.153 (P= 0.762). Conclusions The
operation time of unplanned re-exploration, the worst blood creatinine
value within 48h before the re-exploration, the worst lactate value
within 24h after the re-exploration, cardiac insufficiency, respiratory
insufficiency, and acute kidney injury were independent prognostic
factors of hospital mortality for unplanned re-exploratio after
cardiovascular surgery.
共同體與個體在現代時期的幸福
Authors: TAO Tao
Published: March 2021

LANGUAGE NOTE | Document text in Chinese; abstract in English only.Based on analogical argument, Professor Hans-Martin Sass argues that collective and individual bodies are not independent but interconnected as natural bodies. He worries about modern scientific technologies that aggravate the diseases of the body. I agree with Prof. Sass in many respects but emphasize that modern technology is not the key to the problem. Whether in ancient times or modern times, we have to restate that the ultimate end of life is happiness rather than benefit and that the instrument to pursue happiness is virtue rather than any kind of technology. DOWNLOAD HISTORY | This article has been downloaded 5 times in Digital Commons before migrating into this platform.
應當重視儒家倫理智慧在全球抗疫中的道德價值——范瑞平先生＜大疫當前: 訴諸儒家文明的倫理資源＞一文讀後
Authors: BIAN Lin
Published: March 2021

LANGUAGE NOTE | Document text in Chinese; abstract in English only.In the global fight against the pandemic, in addition to the roles played by politics, economy, science, and other fields, ethical considerations cannot be ignored. Ruiping Fan’s article explains in depth how to incorporate the ethical resources of Confucian civilization into the global anti-epidemic process. It recommends that attention be paid to the natural integration of the Chinese traditional ethical spirit as a cultural phenomenon with the Chinese political system in the fight against the pandemic and to its effectiveness as shown by anti-epidemic practices. With its unique illustration of “essence-energy resonance” to demonstrate the “synchronicity law,” the article is well worth further discussion.DOWNLOAD HISTORY | This article has been downloaded 9 times in Digital Commons before migrating into this platform.
儒家文明的倫理資源是否能夠更好地解決當前的疫情？——讀范瑞平教授＜大疫當前: 訴諸儒家文明的倫理資源＞
Authors: ZHANG Yanliang
Published: March 2021

LANGUAGE NOTE | Document text in Chinese; abstract in English only.This paper summarizes the main ideas and viewpoints of Professor Fan Ruiping’s essay “The Current Epidemic: Appealing to the Ethical Resources of Confucian Civilization” and advances three opinions for discussion. On the one hand, it affirms Professor Fan Ruiping’s contribution in resorting to the ethical resources of Confucian civilization to solve the various dilemmas brought about by the pandemic. On the other hand, it points out that the ethical resources of Confucian civilization are limited in their capacity to solve these dilemmas.DOWNLOAD HISTORY | This article has been downloaded 5 times in Digital Commons before migrating into this platform.
Perancangan Furniture Multifungsi Kamar Kos Mahasiswa di Surabaya dengan Pendekatan Ergonomi
Authors: Heryanto Joel , Hartono Markus , Ronyastra I Made
Published: March 2021

Abstract— Boarding house is one of the vertical dwellings with certain tariffs which are useful as temporary residences, both those who study far from their homes or work in uncertain locations. With ongoing price inflation, the boarding house entrepreneurs will optimize development for their business, one of which will affect the size of the boarding room. Retrieval of data using interview techniques with a sample system. Interviews were conducted so that this study uses an ergonomics approach and product design, so that the products created are suitable and comfortable when used. Ergonomics will be combined with anthropometry, with the aim that the product is created with a very comfortable size and product design is used to help arrange and sort the best product design. The results of data processing get a multifunctional room furniture concept that uses a modern design with a size of 2.2m x 2m x 2m, using full wood raw material and has a bed and folding table, has a drawer and cupboard. This concept will be shown to boarders and boarding entrepreneurs, 90% of 20 resource persons expressed interest in this concept. After calculating the selling price, this product is valued at Rp. 3,050,000. After conducting market testing, no one is interested in buying this product.Keywords: boarding house, design, price

Abstrak— Kos merupakan salah satu hunian vertikal dengan tarif tertentu yang berguna sebagai tempat tinggal sementara, baik itu yang menempuh pendidikan di luar tempat tinggal atau bekerja pada lokasi yang tidak menentu. Dengan inflasi harga berkelanjutan membuat parar pengusaha kos akan mengoptimalkan pembangunan untuk bisnis mereka, salah satunya akan berdampak pada ukuran kamar kos. Pengambilan data menggunakan teknik interview dengan sistem sampel. Interview dilakukan agar Penelitian ini menggunakan pendekatan ergonomi dan perancangan produk, agar produk yang diciptakan sesuai dan nyaman saat digunakan. Ergonomi akan dipadukan dengan antropometri yang bertujuan produk diciptakan dengan ukuran yang sangat nyaman dan perancangan produk digunakan untuk membantu dalam merangkai dan memilah rancangan produk yang paling baik. Hasil dari pengolahan data mendapatkan konsep Furniture kamar multifungsi yang menggunakan desain modern dengan ukuran 2.2m x 2m x 2m, menggunakan bahan baku full kayu serta memiliki ranjang dan meja lipat, memiliki laci dan lemari. Konsep ini akan ditunjukan terhadap penghuni kos dan pengusaha kos, 90% dari 20 narasumber menyatakan berminat terhadap konsep ini. Setelah dilakukan perhitungan untuk harga jual, produk ini dihargai sebesar Rp. 3.050.000. Setelah dilakukan market testing, produk belum ada yang berminat untuk membelinya.Kata kunci: kos, desain, harga
THE INFLUENCE OF SOCIAL AND PSYCHOLOGICAL ATTITUDES OF MODERN SPOUSES ON THEIR MARRIAGE SATISFACTION
Authors: Pospelova Irina , Kosianova Olena
Published: March 2021

The present study analyzes the problem of finding the relationship between the level of marriage satisfaction and
the peculiarities of the social and psychological attitudes of modern spouses. The motivational orientation of modern
spouses has been analyzed. It has been shown that the highest level of marriage satisfaction is observed in “families
with adolescents”, the lowest level – in “mature families”. The interpersonal dealings between the spouses have been
revealed and the most important factors that negatively affect the marriage have been singled out, which include: lack of
emotional support, inflated expectations of marriage, dissatisfaction with the character of the spouse. It is shown that
the more similarity in relation to important areas of life and common motivational orientations and needs the spouses
have, the more level of satisfaction with family life they obtain. The similarity of characters and the presence of similar
values in spouses keep the family together. In contrast, the sharp divergence between the real character of the spouse
and the expectations from him/her is the most influential factor that determines low marriage satisfaction.
RESEARCH METHODS OF EMOTIONAL AND VOLITIONAL POTENTIAL OF HIGHLY QUALIFIED ROWING ATHLETES
Authors: Cheban Yurii
Published: March 2021

The article presents the results of theoretical and empirical study of the issue of diagnosing the level of development of emotional and volitional potential of highly qualified rowing athletes in kayaking and canoeing. The relevance
of the research topic is determined by the importance of emotional and volitional training of athletes to achieve maximum results in sports competitions. The psychological diagnosis of emotional and volitional potential is a necessary
component of such training. The aim of the article is to explore the possibilities of psychological diagnosis of the development level of emotional and volitional potential of highly qualified rowing athletes. It is proposed to use four types of
methods to study the emotional and volitional potential. The first one includes methods for determining the values of
the available emotional and volitional potential on the basis of self-assessment and expert assessment and those which
are based on certain specific test to determine the data of its reserve. The second one is focused on the diagnosis of
various emotional and volitional personality traits such as emotionality, emotional maturity, anxiety, emotional stability,
confidence, perseverance, self-control, etc. The third one includes methods of assessing such personal characteristics as
achievement motivation; the level of development of cognitive processes, characterological features, as well as certain
individual and dynamic data. The fourth one includes means of assessing the skills and abilities of self-stabilization in
the prestarting situation and in the process of solving a competitive issue. The results of approbation the first type of
methods showed that the data obtained through expert assessment of emotional and volitional potential of athletes, selfassessment of athletes` own potential and testing the emotional and volitional capabilities during physical exercises
correspond to the objective achievements of rowers in sporting competitions and their sport qualifications. However,
most of all it concerns the expert assessment.
THE INFLUENCE OF SOCIAL FACTORS ON THE FORMATION OF I. I. MECHNYKOV’S PERSONALITY
Authors: Vynohradova Viktoriia
Published: March 2021

The article deals with the influence of social factors on the development of I. I. Mechnikov’s personality. The implementation of historical and psychological analysis and social and valuable factors that influenced the formation of the
scientist's views have a great importance for building an optimal sociocultural environment in which there is an effective
development of abilities and genius of the child. Creating conditions for personal development is one of the priority
contemporary challenge. The process of I. I. Mechnykov’s personality formation has been considered in the article. The
main purpose of the article is to study the main social factors that influenced the development of I. I. Mechnykov’s personality in the process of growth. Theoretical and biographical methods have been used in the article. Attention has been
paid to the factors of the social spectrum which could influence the formation of the outstanding scientist’s views. The
Mechnykov family have been covered in social and historical conditions. The peculiarities of the educational system in
the years of I. I. Mechnykov’s studies and its influence on the development of his personality have been researched. The
influence of the academic staff on the formation of I. I. Mechnykov’s professional interests and views has been analysed.
The interests of Illia Ilich which directly influenced the formation of the future scientist’s worldview have been also
analysed. The factors that influenced the formation of I. I. Mechnykov’s worldview have been studied. It has been found
out that the formation of I. I. Mechnykov’s personality was influenced significantly by his family, educational environment and development of the scientific sphere. The main factors that influenced the development of I. I. Mechnykov’s
personality were identified as: a noble origin; higher education at the country’s leading university; the influence of prominent scientists who taught at the university; an active position in the educational process, a close interaction with teaching
staff; an active participation in university research; the ability to choose one’s own trajectory and pace of learning independently.
IMPROVING THE CONTENT OF CHOREOGRAPHIC TRAINING IN SPORTS AEROBICS AT THE STAGE OF SPECIALIZED BASIC TRAINING
Authors: Todorova Valentyna , Dolinsky Boris , Pasichna Tetiana
Published: March 2021

The study identified areas for improvement of choreographic training in sports aerobics. The aim is to increase the
effectiveness of choreographic training in sports aerobics at the stage of specialized basic training. The theoretical analysis
and generalization of data of scientific, methodical and special literature, documentary materials, pedagogical observations, surveys have been used in the study. The analysis of the obtained data made it possible to outline areas for improving
the content of choreographic training at the stage of specialized basic training in sports aerobics: creating the latest methods of choreographic training, improving regulations, taking into account the specifics and trends of sports aerobics in
choreographic training software; development of a control system for choreographic readiness; improvement of means of
education of expressiveness, improvement of compositions of competitive programs. The content of choreographic training of athletes at the stage of specialized basic training in sports aerobics, which selected tools and methods to improve
the choreographic training of athletes aged 15-17 years in accordance with modern requirements of the sport has been
improved. The optimal amount of load has been set; means of education of expressiveness and a technique of perfection
of competitive compositions have been introduced, means and methods of control of choreographic readiness of sportsmen have been developed.
Publicidad de automóviles y respeto al medio ambiente: Las limitaciones de la autorregulación publicitaria
Authors: González Moreno Juana María
Published: March 2021

El tráfico rodado es responsable en parte de la crisis medioambiental, como volvió a demostrarse con la reducción de la contaminación en las ciudades que produjo el confinamiento decretado en los primeros meses de este 2020 para hacer frente a la pandemia del coronavirus. Sin embargo, a día de hoy los coches han vuelto a tomar las ciudades y las empresas de automoción redoblan sus esfuerzos en publicidad para aumentar las ventas. Una publicidad cuyo control está a manos de un sistema de autorregulación publicitaria que tiene limitaciones, como explicamos en este trabajo, y que, por tanto, habría de ser regulada jurídicamente de forma más amplia.
The Rare Plants in The Alas Kedaton Tourism Forest, Tabanan, Bali
Authors: Wijana Nyoman , Riawan I Made Oka , Mulyadiharja Sanusi
Published: March 2021

Forests are a source of foreign exchange that has been exploited on a large scale for timber. This exploitation causes a rapid reduction in forest area. Until now, the destruction of the forest environment is still happening, both by illegal logging and illegal mining. This study aims to determine the number of rare plant species in Alas Kedaton Tourism Forest, Tabanan, Bali, Indonesia; and the factors causing the rarity of these plant species. The population in this research is the plant species in Alas Kedaton Tourism Forest. Meanwhile, the social population is all people in the Alas Kedaton Tourism Forest area. The sampling method for plant species is the quadratic method was used to investigate the diversity and the number of rare plants. While for the social sampling was conducted by interviewing with purposive sampling method to the local community around the Alas Kedaton areas. Determination of endangered plant species was conducted by studying of available documents, in-depth interviewing, and seeking information from various existent sources. The collected data analyzed descriptively. The results of this study indicated there are 48 species of plants with 26 families, which are generally found in Alas Kedaton Tourism Forest. Of this number, 42 (87.5%) plant species are included in the rare category; (2) of the 42 species of rare plants in the Alas Kedaton Tourism Forest, there are 8 (19.04%) plant species that are included in the National rare category, 20 (47.62%) rare plant species in Bali, 10 ( 23.81%) rare plant species in Tabanan Regency, and 4 (9.52%) species included in the rare category at the District level (especially Marga District); and (3) factors causing the scarcity of plant species in Alas Kedaton Tourism Forest are (a) past environmental degradation, (b) reproductive problems of rare plants, (c) human intervention, (4) disturbance by animals, especially long tailed monkeys (Macaca fascicularis) and bats (Pteropus vampyrus).