bluuebunny/crossref_metadata_2025 huggingface dataset:
Precipitation effects on parasite, indicator bacteria, and wastewater micropollutant loads from a water resource recovery facility influent and effluent
Authors: Tolouei Samira , Autixier Laurène , Taghipour Milad , Burnet Jean-Baptiste , Bonsteel Jane , Duy Sung Vo , Sauvé Sébastien , Prévost Michèle , Dorner Sarah
Published: July 2019

The variability of fecal microorganisms and wastewater micropollutants (WWMPs) loads in relation to influent flow rates was evaluated for a water resource recovery facility (WRRF) in support of a vulnerability assessment of a drinking water source. Incomplete treatment and bypass discharges often occur following intense precipitation events that represent conditions that deviate from normal operation. Parasites, fecal indicator bacteria, and WWMPs concentrations and flow rate were measured at the WRRF influent and effluent during dry and wet weather periods. Influent concentrations were measured to characterize potential bypass concentrations that occur during wet weather. Maximum influent Giardia and C. perfringens loads and maximum effluent Escherichia coli and C. perfringens loads were observed during wet weather. Influent median loads of Cryptosporidium and Giardia were 6.8 log oocysts/day and 7.9 log cysts/day per 1,000 people. Effluent median loads were 3.9 log oocysts/day and 6.3 log cysts/day per 1,000 people. High loads of microbial contaminants can occur during WRRF bypasses following wet weather and increase with increasing flow rates; thus, short-term infrequent events such as bypasses should be considered in vulnerability assessments of drinking water sources in addition to the increased effluent loads during normal operation following wet weather.
Effect of Cu(II) on adsorption of tetracycline by natural zeolite: performance and mechanism
Authors: Guo Xuan , Wang Pengchao , Li Peng , Zhang Chengjun
Published: July 2019

The purpose of this study was to investigate the effect of Cu(II) on the adsorption performance and mechanism of tetracycline (TC) adsorption by natural zeolite (NZ) in aqueous solution. Low levels of Cu(II) (<0.01 mmol/L) enhanced the extent of TC adsorption from ∼0.4 mg/g (in the absence of Cu(II)) to ∼0.5 mg/g (with 0.01 mmol/L Cu(II)), resulting in 99% removal of the total TC content. The TC adsorption gradually decreased with increase in the initial pH, but the coexistence of Cu(II) lowered the extent of decrease. The adsorption process was better simulated by the pseudo-second-order kinetics model, but the isotherm model that was more fitting changed from the Langmuir to the Freundlich model as Cu(II) increased, indicating the coexistence of Cu(II) and TC altered the adsorption mechanisms. However, the residual TC in solution increased from 0 to ∼6 mg/L as the concentration of Cu(II) increased from 0 to 1 mmol/L, suggesting a competition between TC and Cu(II) for the adsorption sites in NZ. Fourier transform infrared spectroscopy analysis showed that the functional groups on the surface of NZ changed after the adsorption of TC, suggesting that complex reactions had occurred on the surface of the adsorbent.
Confirmation the optimal aeration parameters for nitrogen removal and nitrous oxide emission in wastewater ecological soil infiltration systems with brown earth
Authors: Sun Yafei , Pang Junling , Wang Shiyao , Tao Tingting , Fu Xun , Zhang Ying , Sun Bo , Pan Jing
Published: July 2019

Nitrogen removal is an obstacle for the wide application of wastewater ecological soil infiltration (WESI) system in domestic wastewater treatment. In this study, matrix dissolved oxygen (DO), nitrogen removal and nitrous oxide (N2O) emission in aerated pilot WESI systems were investigated under different aeration times (1, 2, 3, 4 and 6 h/d) and aeration rates (1, 2, 3 and 4 L/min). The results showed that aerobic conditions in upper matrix and anoxic or anaerobic conditions in the subsequent matrix were developed in an aerated/non-aerated cycle at the optimal aeration condition of aeration time of 4 h/d and aeration rate of 3 L/min. Simultaneously, high removal efficiency of chemical oxygen demand (COD) (97.9%), NH4+-N (98.2%), total nitrogen (TN) (90.7%) and low N2O emission rate (13.2 mg/(m2 d)) were obtained. The results would provide optimal aeration parameters for application of intermittent aerated WESI systems.
Potential Drug Targets Against Hepatitis B Virus Based on Both Virus and Host Factors
Authors: Zhang Bing-Yi , Chai Dan-Ping , Wu Yi-Hang , Qiu Li-Peng , Zhang Yong-Yong , Ye Zi-Hong , Yu Xiao-Ping
Published: July 2019

Background:

Hepatitis B is a very harmful and epidemic disease caused by hepatitis B virus (HBV). Although an effective anti-HBV vaccine is available, chronic infection poses still a huge health burden in the whole world. The present anti-HBV drugs including nucleoside analogues and interferonalpha have their limitations without exception. There is no effective drug and therapeutic method that can really and truly cure hepatitis B so far. The variability of HBV genome results in that a significant number of patients develop drug resistance during the long-term use of anti-HBV drugs. Hence, it is urgently needed to discover novel targets and develop new drugs against hepatitis B.

Objective:

The review aims to provide the theory support for designing of the anti-HBV innovative drugs by offering a summary of the current situation of antiviral potential targets.

Results and Conclusion:

Since HBV is obligate intracellular parasite, and as such it depends on host cellular components and functions to replicate itself. The targeting both virus and host might be a novel therapeutic option for hepatitis B. Accordingly, we analyse the advances in the study of the potential drug targets for anti-HBV infection, focusing on targeting virus genome, on targeting host cellular functions and on targeting virus-host proteins interactions, respectively. Meanwhile, the immune targets against chronic hepatitis B are also emphasized. In short, the review provides a summary of antiviral therapeutic strategies to target virus factors, host factors and immune factors for future designing of the innovative drug against HBV infection.
Aptamers in Drug Design: An Emerging Weapon to Fight a Losing Battle
Authors: Jose Jobin , Thomas Aaron Mathew , Mendonsa Darewin , Al-Sanea Mohammad M. , Uddin Md. Sahab , Parambi Della Grace Thomas , Charyulu R Narayana , Mathew Bijo
Published: July 2019

Implementation of novel and biocompatible polymers in drug design is an emerging and
rapidly growing area of research. Even though we have a large number of polymer materials for various
applications, the biocompatibility of these materials remains as a herculean task for researchers.
Aptamers provide a vital and efficient solution to this problem. They are usually small (ranging from
20 to 60 nucleotides, single-stranded DNA or RNA oligonucleotides which are capable of binding to
molecules possessing high affinity and other properties like specificity. This review focuses on different
aspects of Aptamers in drug discovery, starting from its preparation methods and covering the recent
scenario reported in the literature regarding their use in drug discovery. We address the limitations
of Aptamers and provide valuable insights into their future potential in the areas regarding drug
discovery research. Finally, we explained the major role of Aptamers like medical imaging techniques,
application as synthetic antibodies, and the most recent application, which is in combination with
nanomedicines.
Estrogen Deprivation and Myocardial Infarction: Role of Aerobic Exercise Training, Inflammation and Metabolomics
Authors: Ruberti Olívia M. , Rodrigues Bruno
Published: July 2019

In general, postmenopausal women present higher mortality, and worse prognosis after myocardial infarction (MI) compared to men, due to estrogen deficiency. After MI, cardiovascular alterations occur such as the autonomic imbalance and the pro-inflammatory cytokines increase. In this sense, therapies that aim to minimize deleterious effects caused by myocardial ischemia are important. Aerobic training has been proposed as a promising intervention in the prevention of cardiovascular diseases. On the other hand, some studies have attempted to identify potential biomarkers for cardiovascular diseases or specifically for MI. For this purpose, metabolomics has been used as a tool in the discovery of cardiovascular biomarkers. Therefore, the objective of this work is to discuss the changes involved in ovariectomy, myocardial infarction, and aerobic training, with emphasis on inflammation and metabolism.
Aligned Expression of IFI16 and STING Genes in RRMS Patients’ Blood
Authors: Helbi Sobhan , Ravanbakhsh Behnam , Karimi Mohammad , Kooti Wesam , Jivad Nahid
Published: July 2019

Objective:

Multiple sclerosis (MS) is a chronic neurodegenerative disease of the central
nervous system. The most common disease phenotype is Relapsing-Remitting MS (RRMS). Beta interferons
are the first line of RRMS patients’ treatment. Interferon-inducible protein 16 (IFI16) as a DNA
sensing molecule and its downstream complex stimulator of interferon genes (STING) play a critical
role in the activation of type I interferons. Hence we aimed to evaluate the expression rate of IFI16 and
STING in RRMS patients’ blood under a different type of IFNβ treatment.

Methods:

In the present study, 99 individuals participated. The participants were divided into 4 groups:
28 control subjects, 25 new cases of RRMS patients, 25 RRMS patients treated with IFNβ-1a (B1a), 21
RRMS patients treated with IFNβ-1b (B1b). The EDTA-treated blood samples were taken and transferred
at standard conditions to the Cellular and Molecular Research Center of Shahrekord University
of Medical Sciences, RNA was extracted and converted into cDNA. To evaluate the expression of
IFI16 and STING, the Real-Time PCR method using SYBR Green/ROX qPCR master mix was performed
done. The level of genes expression was measured using 2–ΔΔCt method. The obtained data
were analyzed using SPSS v22 software.

Results:

Comparison of the IFI and STING mRNA expression in blood samples in association with
gender and age showed no significant differences (p>0.05). Also, the evaluation of IFI16 mRNA level
revealed that the IFI16 genes’ expressions were remarkably higher in the new case group compared to
the control group, however, STING expression did not show any significant difference. The mRNA
levels of IFI16 and STING in IFNβ-treated groups were significantly lower than the new case group
(p<0.001). Also, the genes’ expressions in both the IFNβ-treated groups were significantly lower compared
to the control group (p<0.001). In the assessment of the correlation of IFI16 and STING expressions
with age and sex in different research groups, no statistically significant differences were seen
(p>0.05).

Conclusion:

Perhaps the IFNβ therapy decreases the IFI16 and STING expression in a STINGdependent
pathway as a negative feedback mechanism for regulation of the immune system and suppression
of pro-inflammatory cytokines production. The important role of DNA sensing molecules and
STING-dependent pathway in MS gives a new insight into future treatment based on STING-direct
therapies.
Antinutrients in Plant-based Foods: A Review
Authors: Popova Aneta , Mihaylova Dasha
Published: July 2019

Modern society has easy access to a vast informational database. The pursuit of sustainable green and healthy lifestyle leads to a series of food choices. Therefore, it is of importance to provide reliable, comprehensive and up-to-date information about food content including both nutritional and antinutritional elements.

Nutrients are associated with positive effects on human health. Antinutrients, on the other hand, are far less popular for the contemporary man. They are highly bioactive, capable of deleterious effects as well as some beneficial health effects in man, and vastly available in plant-based foods. These compounds are of natural or synthetic origin, interfere with the absorption of nutrients, and can be responsible for some mischievous effects related to the nutrient absorption. Some of the common symptoms exhibited by a large amount of antinutrients in the body can be nausea, bloating, headaches, rashes, nutritional deficiencies,etc. Phytates, oxalates, and lectins are few of the well-known antinutrients.

Science has acknowledged several ways in order to alter the negative influence antinutrients exhibiting on human health. Mechanical, thermal and biochemical approaches act synergistically to provide food with lower antinutritional levels.

The purpose of this review was to synthesize the availability of antinutrients, clear their effect on the human body, and commemorate possible paths to disable them. This review provides links to the available literature as well as enables a systematic view of the recently published research on the topic of plant-based antinutrients.
Comparison Between Major Types of Arthritis Based on Diagnostic Ultrasonography
Authors: Roy Homagni Sikha , Cheng Chunxia , Zhu Qing , Yue Luo , Yang Shiyan
Published: July 2019

Background:

Ultrasound has been widely used in clinical settings for the assessment of different types of Arthritis as well as in their management. This Review study assessed the diagnostic value of Ultrasonography in comparison with major types of Arthritis namely Osteoarthritis (OA), Rheumatoid Arthritis (RA), Gouty Arthritis (GA), Pseudogout (Calcium Pyrophosphate Deposition Disease - CPPD), Psoriatic Arthritis (PA), Infectious Arthritis (IA) and Spondyloarthritis (SA).

Methodology:

Computerized literature search of PubMed was conducted from 1990 to present, for publications in English on diagnostic ultrasonography and major types of arthritis. A total of 206 publications were identified. Experimental and clinical studies that focused on the ultrasound features of the major types of Arthritis were accepted. A total of 52 out of the 206 publications, met our search criteria. Among these, 12 studies focused on OA, 7 on RA, 7 on GA, 5 on CPPD, 10 on PA, 4 on IA, and 7 on SA. From all the studies, some distinctive US features are reviewed for each of the major arthritis. Some of the features were unique and some overlapped.

Conclusion:

Ultrasound may demonstrate the ability to differentiate between the major types of Arthritis on a basic level when combined with history and physical examination. This can prove to be beneficial in the early diagnosis of the major types of arthritis, but with few limitations. This review literature shows that Ultrasound can be very helpful in bed side analysis of the major types of arthritis as well as in differentiating between them, because this modality besides being non-invasive is also very cheap.
Innovative Structural Solutions for Prefab Reinforced Concrete Hall-Type Buildings
Authors: Sorace Stefano , Terenzi Gloria
Published: July 2019

Background:

The anti-seismic design of prefab reinforced concrete buildings is usually carried out with a conventional ductility-based approach. This implies a remarkable plastic demand on columns, as well as damages to the connections of structural and non-structural members, for seismic events with comparable intensity to the basic design earthquake normative level.

Objective:

In view of this, a study was developed and aimed at extending to the field of new prefab reinforced concrete structures the application of advanced seismic protection strategies, capable of guaranteeing undamaged response up to the maximum considered earthquake normative level.

Method:

A benchmark building was designed as demonstrative case study for this purpose, in the three following hypotheses: (a) according to a traditional ductility-based approach; (b) by incorporating dissipative bracings, equipped with fluid viscous dampers; (c) by placing a seismic isolation system at the base, composed of a set of double curved surface sliders.

Results:

The results of the verification analyses show that the targeted performance for the design solutions b) and c) is obtained with sizes of columns and plinths notably smaller than those for the conventional design. This allows compensating the additional cost related to the incorporation of the protective devices, for the dissipative bracing system, and limiting additional costs below 25%, for the base isolation solution. At the same time, a supplemental benefit of the latter is represented by greater protection of contents and plants, as they are fully supported by the seismically isolated ground floor.

Conclusion:

The study highlights the advantages offered by the two advanced seismic protection technologies in an unusual field of application, guaranteeing an enhanced performance of structural and non-structural elements, as well as reduced member sizes, as compared to the traditional ductility-based design.
The Importance of Interior Architecture to Meet Residents’ Needs in Gated Communities in Cairo
Authors: Abdallah Karam
Published: July 2019

The city of Cairo - since the beginning of the third millennium - has witnessed a constructional expansion of new cities for people of class A to live within gated communities, which provide luxury and safety. This research aims to identify the tangible and intangible needs from the occupants’ and the interior designer’s perspective, due to the diversity of these needs. The identification of these demands may help to clarify the requirements provided by the large construction companies, which will highlight the role of the interior designer in the design process of the residential units.Keywords: Interior design in Egypt, Contemporary Egyptian residences, Egyptian residential needs, Gated communities in Egypt.eISSN: 2398-4287© 2019. The Authors. Published for AMER ABRA cE-Bsby e-International Publishing House, Ltd., UK. This is an open access article under the CC BYNC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, UniversitiTeknologi MARA, Malaysia.DOI: https://doi.org/10.21834/e-bpj.v4i11.1727
Memorias del primer Simposio Nacional de Ciencias Agronómicas
Authors: Suárez Padrón Isidro Elias , Salgado Chávez José Alberto , Vergara Carvajal Amir David , Mercado Fernández Teobaldis , Araméndiz Tatis Hermes , Saavedra De Castro Enrique , Martínez Remberto , Pérez José Luis , Rosero Amparo , Burbano Esteban , Pastrana Iván , Carvajal Valderrama Evaristo , Arcia Miranda Adrián José , Pérez Carlos A. , López Claudia M. , Rodríguez Ortiz Jaime Andrés , Gamboa Tabares Jean Alexander , Gonzalez Chingate Erika , Díaz Jiménez Kevin , Liévano Silva Kevin , Gómez Triana Angélica , Alemán Ivón , Doria José , Combatt Caballero Enrique , Pardo Yuri , Palencia Manuel , Alpala Deisy Rosero , Rodrigues Santana Santina , Rosero María Gladis , Olmos González Pedro Miguel , Tovar Ortega Antonio Segundo , Sampedro Marin Alcides Casimiro , Pájaro Fernández Sol Mirena , Valencia Agresoth Robert , Mercado Lázaro Jaime , Cuellar Higuera Lorena , Avellaneda Torres Lizeth Manuela , García Jorge , Burbano Oscar , Flórez Faura Rafael , Bedoya Rodríguez Tatiana , Aldana Rojas Andrés , Grandett Martinez Liliana María , Espinosa Carvajal Manuel Ramón , Rodríguez Pinto María del Valle , Tordecilla Zumaqué Lilibet , Luna Castellanos Lily Lorena , Granda Leiter , Pluháčková Helena , Cerkal Radim , Sierra Carlos , Espitia Laura , Araujo Hernando , Morelo Julio , Novoa Yánez Rafael Segundo , López Rebolledo Leonardo Andrés , Rosero Elvia Amparo , Orozco Rafael , De la Ossa Víctor , León Rommel , Cordero Carina , Villalba Leonardo , Rodriguez Eberto , Garavito Lina , Osorio Omar , Perez Jose Ives , Segura Jaydy , Lenis Jorge Iván , Salazar Sandra , Belalcazar John , Morante Nelson , Ceballos Hernán , Peña Murillo Francisco Javier , Cardona Ayala Carlos Enrique , Espitia Camacho Miguel Mariano , Martínez Reina Antonio M. , Solís Tuberquia Wilson , Jaraba Navas Juan , Sánchez López Diana Beatriz , Rodríguez Pinto María , Rubiano Rodríguez José , Arroyo Erika , Beltrán Herrera Javier Darío , Reyes Diarco Anderson Mauricio , Ochoa Cifuentes Alejandro , Múnera Bedoya Oscar D. , Vásquez Bettin Ana Milena , Agudelo Genaro Andrés , Quintero Irma , Carbonó Eduino , Lora Jorge , Peña Anuar , Julio Gomez Samir David , Maya Duran Hernán José , Viloria Sánchez Mayra , Londoño Padilla Isaías , García Zapata Andrés F , Barrios Pérez María L. , López Sánchez Javier Gustavo , Chica Álvarez Martha O. , Quintero Flórez Pedro E. , Rivera Hernández Juan F. , Pérez Pazos Jazmín Vanessa , Rico Peña Ruth Esther , Miranda Parada Angie Guadalupe , Jair Villamizar Cristian , Castellanos Leonides , Pérez Cantero Shirley , Romero Ferrer Jorge Luis , Morales Angulo José Gregorio , Cadena Torres Jorge , Regino Sol Mara , Pico Diego A. , Tamara Morelos Ricardo Enrique , García Peña Joaquín Alfonso , Espitia Montes Amaury Aroldo , Vargas Castro Fernando , Patiño Gelber Rosas , Sierra Monroy Janeth Alexandra , Díaz Cabadiaz Abelardo Tulio
Published: July 2019

Primer simposio nacional de Ciencias Agronómicas: El renacer del espacio de discusión científica para el Agro colombiano.
Good Artists Torrent, Great Artists Fork
Authors: Hokanson Taylor , Bontrager Nick
Published: July 2019

In this workshop, Professors Nick Bontrager and Taylor Hokanson introduce the tools and services required to fabricate printed circuit boards, or PCBs. The process is more accessible than ever before, and is cheap enough to allow individuals to obtain functional prototypes, in small quantities, that are indistinguishable from similar PCBs that might be produced in the hundreds of thousands for industry or commercial applications. Using an “unpopulated” demonstration board designed by the workshop co-chairs, participants walk through all the steps needed to assemble and solder surface-mount components, finishing the event with a battery-operated, wearable, LED light display.
THE EFFECT OF BLENDED LEARNING TOWARD MEMORY RETENTION RATES OF NEONATAL RESUSCITATION SKILLS AND STUDENT’S PERCEPTION
Authors: Veratiwi Veratiwi , Sekarwana Nanan , Husen Ike Rostikawati
Published: July 2019

Background: Retention is a goal in the learning process. The objective of this study was to compare the memory retention rates of neonatal resuscitation skills between blended learning strategies and conventional ones and to analyze the correlation of students’ perception on the implementation of blended learning towards memory retention rates of neonatal resuscitation skills.Method: This was an analytical study using quasi-experimental design applying posttest-only non-equivalent group design. The subjects of this study were students of DIII Midwifery Program of Health Polytechnic Palembang. The research subjects were divided into two groups; 25 subjects in blended learning group and 25 subjects in conventional group. The hypotheses were tested using Kolmogorov-Smirnov, to analyze the differences of memory retention rates of resuscitation skills between the two groups of study, and Chi-square test, to see the correlation of students’ perception on the implementation of blended learning with memory retention rates of resuscitation skills.Result: The results of study showed that the memory retention rates of neonatal resuscitation skills between blended learning group and conventional group were not significantly different. In addition, there was no correlation of students’ perception on the implementation of blended learning toward the memory retention rates of resuscitation skill.Conclusion: From the findings of this study, it can be concluded that there was no difference in the memory retention rates of neonatal resuscitation skills between blended learning strategies and conventional ones and there was no effect of the students’ perception on the implementation of blended learning towards the memory retention rates of neonatal resuscitation skills.
CORRELATION OF STUDENT PERCEPTIONS ON LEARNING ENVIRONMENT, PARTICIPATION, AND ACADEMIC PERFORMANCE IN A MEDICAL SCHOOL
Authors: Sukmawati Yusril Rahmi , Sari Dian Puspita , Susani Yoga Pamungkas
Published: July 2019

Background: Student perceptions of the learning environment can influence student participation in learning. Both of these variables can possibly affect students’ academic performance. The purpose of this study was to assess the correlation between perceptions of the learning environment, participation in PBL tutorials, and academic performance of the pre-clinical stage students of the Faculty of Medicine Universitas Mataram.Methods: This was a cross-sectional study. Student perceptions of the learning environment were assessed using The Dundee Ready Education Environment Measure (DREEM) questionnaire. Participation in PBL tutorials was measured by an instrument that assess preparation for the tutorial, interactions during the tutorial, and students’ self-management. Academic performance was measured from the block’s main exam score. A total of 286 out of 303 medical students from year 1 to year 4 (94.39%) participated in this study.Results: The mean of the total DREEM score, participation score, and academic performance respectively were135.94 ± 17.27; 83.20 ± 9.48; and 61.48 ± 13.47. There was a correlation between student participation and academic performance (r 0.569, p < 0.001), student perceptions of the learning environment and student participation (r = 0.225, p < 0.001), and student perceptions of the learning environment and academic performance (r = 0.190, p < 0.001).Conclusion: Student participation in tutorials is related to student academic performance. Participation possibly mediates the relationship between student perceptions of the learning environment and academic performance.
Evaluación de la aptitud clínica de los médicos pasantes en servicio social
Authors: Gómez López Víctor Manuel , Rosales Gracia Sandra
Published: July 2019

Introducción: La evaluación de la aptitud clínica de los médicos pasantes en servicio social, es un indicador prioritario para la mejora en la formación de los recursos humanos para la atención de la salud. Objetivo: Evaluar el nivel de la aptitud clínica global y por indicadores, que muestran los médicos pasantes en servicio social, en la atención de los diez principales motivos de consulta en el primer nivel de atención. Método: Se realizó un estudio cuantitativo, descriptivo, observacional y transversal, en una escuela de medicina del sector privado. Se aplicó un cuestionario, con una validación desde el punto de vista de contenido, a una muestra poblacional de ochenta alumnos. Los padecimientos incluidos en la evaluación de la aptitud clínica fueron los diez principales motivos de consulta en el primer nivel de atención, de la cual solo se integraron seis componentes. Se utilizó estadística descriptiva e inferencial considerando un valor de p ≤ a 0.05 como estadísticamente significativo. Resultados: El promedio global de calificación de los alumnos en todos los casos presentados fue de 66.6 (± 9.5) con un valor mínimo de 53.5 y máximo de 98.0. Se observó un mejor resultado de la aptitud clínica, en la diabetes mellitus y sus complicaciones, así como en la preeclampsia-eclampsia. En el 60% de los participantes, el nivel de aptitud clínica global para la atención de los principales motivos de consulta en el primer nivel de atención, considerando el azar se ubicó en el nivel medio.No hubo diferencias según sexo. Conclusiones: La aptitud clínica global de los pasantes de medicina para la atención de los principales motivos de consulta es adecuada.
Las tecnologías del aprendizaje y del conocimiento (TAC) y la formación integral y humanista del médico
Authors: Parra Acosta Haydeé , José López Loya José , González Carrillo Eliazar , Moriel Corral Leticia , Vázquez Aguirre Alma Delia , González Zambada Nora Cecilia
Published: July 2019

Introducción: Con los avances de las tecnologías y el internet de todas las cosas, se generan nuevas perspectivas en la formación de los médicos. De ahí la importancia de utilizar las tecnologías del aprendizaje y del conocimiento (TAC) que corresponden a las tecnologías de información (TIC) y comunicación orientadas a procesos pedagógicos para favorecer la formación humanista.

Objetivo: Mostrar la relación que existe entre la aplicación de las TAC, con la formación integral y humanista del médico por competencias.

Método: Estudio transversal no experimental, que se realizó mediante la aplicación de un instrumento, tipo cuestionario, a 152 estudiantes y 35 docentes de medicina, que mide la percepción que tienen de la formación humanista a través de las TAC. El cuestionario integró 63 ítems que se respondieron mediante una escala centesimal. Fue validado a través de un grupo piloto obteniendo un alpha de Cronbach de 0.92.

Resultados: Los resultados descriptivos mostraron que existe tendencia en considerar que la aplicación de las TAC en la formación médica contribuye más al desarrollo integral (87.60), al desempeño académico (83.8) y al desarrollo de competencias (80.80), que a la formación humanista (58.9). Sin embargo, se observó una relación significativa entre la educación médica a través de las TAC y la formación humanista del médico (r. 0.82). Lo cual indica que la percepción que tienen los docentes y estudiantes, no solo es distinta a los resultados correlacionales, sino que predisponen la formación de los médicos acorde a los retos del contexto socioeducativo actual.
Simulación y aprendizaje centrado en el paciente
Authors: Sánchez  Aparicio Enrique , López Salazar Luis Humberto
Published: July 2019

La simulación clínica se sustenta como una estrategia educativa que incorpora la práctica deliberada que mejora los resultados para lograr competencias deseables en comparación con la práctica clínica tradicional. De aquí que en instituciones educativas existe interés por desarrollar centros de simulación con base en tecnología de alta fidelidad.
Peer-assisted learning en lectura crítica de la investigación en internado de pregrado
Authors: Cobos-Aguilar Hécto
Published: July 2019

Introducción: El peer-assisted learning es una estrategia educativa con resultados adecuados en el aprendizaje de habilidades como la clínica e investigación. Se ha implementado en Nuevo León desde hace siete años. Objetivo: Describir la experiencia del peer-assisted learning en lectura crítica de investigación en el internado de pregrado. Método: Durante cada semestre, por siete años, a los internos de pregrado se les ofreció un curso de investigación por lectura crítica, que incluyó los diseños de casos y controles, pruebas diagnósticas, cohortes, ensayo clínico aleatorizado, seguimiento, metanálisis, encuestas e instrumentos. El curso con evaluación inicial y final, duró 16 semanas, con frecuencia semanal y 90 minutos de duración, e incluyó la revisión crítica de artículos a través de una guía con reactivos que exploraban la interpretación, juicio y propuestas a los autores y que sirvió para la argumentación. Las tareas se enviaban al profesor para su evaluación. Para reproducir el curso, se seleccionaron a los alumnos tutores por asistencia, elaboración de tareas, argumentación, empatía, alto desempeño en la evaluación final y aceptación voluntaria. Desarrollaron el curso referido antes, entre uno a tres por grupo. Con la prueba de Wilcoxon se compararon los resultados iniciales y finales en cada grupo. Resultados: Se conformaron 15 grupos, con 22 alumnos tutores y 242 internos de pregrado. Excepto dos, todos los grupos avanzaron (p < 0.05).Discusión: Los resultados de la implementación del PAL por varias generaciones en la lectura crítica de informes de investigación en pregrado, ofrecen una alternativa difupara el desarrollo de habilidades docentes y de investigación en los alumnos. Debe apoyarse formalmente esta actividad de manera extracurricular o incorporarla al plan de estudios pues sus efectos benéficos son personales, grupales e institucionales.
Mercado laboral de los comunicadores corporativos en las organizaciones en Colombia
Authors: Ocampo-Villegas María Cristina
Published: July 2019

El entorno en el que se desempeñan los comunicadores corporativos en Colombia exige nuevas competencias laborales que las instituciones de educación superior deben considerar. Este trabajo busca responder a: ¿cuáles son las características de la demanda laboral de los comunicadores orientados hacia el trabajo corporativo en Colombia? Y ¿cuáles las competencias en que se les debería formar? El objetivo es conocer las características de las oficinas de comunicación de las empresas colombianas y sus expectativas frente a la formación de los comunicadores. El estudio se basó en una encuesta realizada a los encargados de los departamentos de comunicación de 259 grandes empresas colombianas, entre mayo y junio de 2017. Se encontró que las empresas prefieren contratar publicistas a comunicadores, y que las competencias esperadas por el mercado se enfocan más en el hacer que en el pensar. Los resultados permitirán orientar los programas universitarios de comunicación en este país.
A Monitoring System of Ankle Rehabilitation For Paralyzed Patients Using Android Aplication
Authors: Arrosida Hanum , Setiarini Asih , Winarno Basuki , Sudaryanto Albert
Published: July 2019

A Monitoring system of ankle rehabilitation for paralyzed patients was successfully designed. The monitoring application on Android smartphone was made app inventor. This application uses bluetooth HC-05 as a data transmission between the ankle therapy aids and smartphone Android. A MPX5050DP sensor is used to determine the muscle condition of the paraplegic to measure the muscle strength scale and control the motor dc speed of ankle rehabilitation hardware. The virtual keys on the application are five instructions of therapeutic movement such as, dorsiflexion (200), plantarflection (450), eversion (100), inversion (100) and patterned of movement. The access time to operate the ankle rehabilitation hardware is 0.8 seconds. This application includes an alarm and a database that can be used as a monitoring system. An alarm menu serves as a reminder for patients to take therapy and database to store data readings of sensors that converted into scale and muscle pressure. A MPX55050DP sensor output is displayed on smartphone application, stored in database and the therapy results are reserved to document format. The capacity of the database corresponds to the memory on the smartphone. Based on the measurement results, the ankle therapy application on android smartphone can control the system movement of ankle therapy aids and as a monitoring system of therapy results for paralyzed patients and make easily in analyzing the condition of leg muscle strength.
Creating a Circular Tower Defense Game: Development and Game Experience Measurement of Orbital Defense X
Authors: Asfarian Auzi , Ramadhan Wiradani , Putra Widi Aryaguna , Raharjanto Gabriel Muhammad , Frisky Rakish
Published: July 2019

In this paper, we propose a new style of tower defense game by using the circular placement of the tower. In this game, dubbed Orbital Defense X, the player must protect the earth with a circle of defensive tower circled around it. The game is developed using game development lifecycle from initiation phase through alpha version. To test the quality of the developed game, we measure the game experience using game experience questionnaire. The questionnaire is divided into three: core, social presence, and post-game questionnaire. The results show that male participant gains a significantly higher score than female participants. Overall, the game experience is received better by the male participant in the core and social presence components, with an average score of 2,27 vs 1,92 and 2,15 vs 1,86. However, in post-game experience, the female participant scores higher with 2,15 vs 1,95. The participant that previously played another tower defense game gave score more in the core, social presence, and post-game experience than the participant that haven’t played it before. Their score is 1,93 vs 2,37 in core, 1,67 vs 2,39 in social presence, and 2,07 vs 1,91 in post-game experience. The result also suggests for more attention in the challenge regarding the enemies (variety and difficulty) rather than more complex tower management system. The social ranking also suggested by the participant to improve the overall experience of this game.
A Combination of Hill CIPHER-LSB in RGB Image Encryption
Authors: Megantara Rama Aria , Rafrastara Fauzi Adi , Mahendra Syafrie Naufal
Published: July 2019

The progress of the development of digital technology today, many people communicate by sending and receiving messages. However, along with extensive technological developments, many crimes were committed. In avoiding these crimes, data security needs to be done. Form of data security in the form of cryptography and steganography. One of the cryptographic techniques is the hill cipher algorithm. Hill ciphers include classic cryptographic algorithms that are very difficult to solve. While the most popular steganography technique is Least Significant Bit (LSB). Least Significant Bit (LSB) is a spatial domain steganography technique using substitution methods. This study discusses the merging of message security with hill cipher and LSB. The message used is 24-bit color image for steganography and text with 32, 64 and 128 characters for cryptography. The measuring instruments used in this study are MSE, PSNR, Entropy and travel time (CPU time). Test results prove an increase in security without too damaging the image. This is evidenced by the results of the MSE trial which has a value far below the value 1, the PSNR is> 64 db, the entropy value ranges from 5 to 7 and the results of travel time <1 second.
Egg Quality Detection System Using Fuzzy Logic Method
Authors: Mahesa Ikbar , Putrada Aji Gautama , Abdurohman Maman
Published: July 2019

Determining the quality of eggs in general is used by placing eggs on a flashlight. The detection system is very necessary to determine good egg quality or rotten eggs, so that the conditions of the eggs can be known by the chicken farm company and then will be sold to the community. This egg detecting system utilizes several sensor devices that are combined. The sensor used to detect the quality of eggs is a light sensor and a heavy sensor by connected with a microcontroller. So that there is no ambiguity towards the decision making of good egg or rotten eggs, then processing the data is obtained from these sensors using Fuzzy Logic and Firebase methods in real time as data storage media, and actuators will distribute or separate good eggs or the rotten eggs one. With the development of technology now, we can use the Internet of Things (IoT) technology, one of the systems check the quality of eggs which are good or not good. This system is built using a microcontroller to coordinate the running of the system using the Fuzzy Logic Method that applies inside. Final information is obtained on the form of egg quality in real time. The test results were carried out using the Fuzzy Logic method and obtained 95% results from 20 eggs and had 1 wrong egg. When using system hardware without using the fuzzy logic method on the microcontroller that using only a light sensor and a heavy sensor it produces a result of 75% from 20 eggs and had 5 wrong eggs. Using the egg detection optimization method can be increased up to 20%.
Avoiding post-truth environmental conflict in New Zealand: communicating uncertainties in endangered species science
Authors: Palliser Anna , Dodson Giles
Published: July 2019

Keyes [2004, p. 15] says: “In the post-truth era we don't just have truth or lies but a third category of ambiguous statements that are not exactly the truth but fall short of a lie”. In this paper about Hector's and Maui dolphin management in New Zealand, we argue that some scientific knowledge about these species presented and disseminated in ways that equate to this third category and as such may be classed as ‘post-truth type communication’. This generates citizen mistrust in science, scientists and government agencies and inflames conflict among informed stakeholders. We argue trust may be rebuilt by a combination of deliberative approaches to environmental governance, transparency about uncertainties, information gaps and divergent scientific opinions, and reformulation of normal scientific approaches and assumptions to those advocated by post-normal science.
Respuesta clínica completa postneoadyuvancia en cáncer de recto estadio III: observación o cirugía
Authors: Torres Mesa Pilar Adriana
Published: July 2019

La respuesta clínica completa posterior a la terapia neoadyuvante del cáncer localmente avanzado de recto, se ha considerado suficiente para la implementación de una estrategia no quirúrgica, de observación y seguimiento por algunos autores. El manejo estándar de esta patología es la realización de manejo quirúrgico oncológico radical del tumor primario, 6 a 10 semanas posterior a la finalización de la neoadyuvancia. En esta revisión se exponen los pros y contras de cada propuesta y se describen las implicaciones y recomendaciones de cada alternativa de manejo
Enfermedad de Crohn. Enfoque diagnóstico y terapéutico de las primeras visitas
Authors: Márquez Velásquez Juan Ricardo
Published: July 2019

La enfermedad de Crohn (EC) es protagonista fundamental de la llamada enfermedad inflamatoria intestinal (EEI), término con el que se conocen varias entidades cuyo origen es multifactorial y se caracterizan por un fenómeno inflamatorio, crónico, recurrente con diferentes grados de afectación sobre el tubo digestivo; pero además con compromiso potencial de otros órganos.

En la última década ha habido un renovado interés en dichas entidades, debido a un auge en medicamentos novedosos, a pesar de lo cual estas siguen siendo incurables. Lo anterior asociado a una incidencia creciente de dicha patología en nuestro país nos obliga tanto científica como moralmente a elaborar unos lineamientos básicos, prácticos con listas de chequeo adaptadas a nuestro medio para el enfoque diagnóstico y seguimiento a través de las primeras consultas del paciente con EC.
Gastroenteropatía eosinofílica. Reporte de un caso y revisión de la literatura
Authors: Roberto A Sandra , Bonilla Rómulo , Pérez G. Gabriel
Published: July 2019

Introducción: la gastroenteropatía eosinofílica es una enfermedad rara caracterizada por infiltración de eosinófilos en una o más capas a diferentes niveles del tracto grastrointestinal, siendo común en estómago y duodeno. Aunque en la mayoría de los casos se presenta con dolor abdominal, también puede aparecer vómito, diarrea, ascitis y pérdida de peso. Reporte de caso: hombre de 41 años con cuadro clínico de 9 meses de evolución de dolor abdominal súbito e intermitente, de predominio en mesogastrio irradiado a región lumbar, manejado con antiespasmódicos sin mejoría. Antecedentes de: infarto agudo de miocardio 2 años atrás con arterias coronarias sanas según angiografía, nefrectomía derecha hace 11 años por hidronefrosis, diagnóstico y tratamiento desde hace 3 años de anemia microcítica hipocrómica con hipereosinofilia, apendicitis aguda hace 7 meses con hallazgos en la patología de infiltrados eosinofílicos, y una biopsia de médula ósea que reveló eosinofilia. Al examen físico: signos vitales normales, ruidos intestinales aumentados en intensidad y frecuencia (40/min) y mesogastrio doloroso a la palpación; sin masas ni visceromegalias. Sus laboratorios revelaron anemia y eosinofilia de 16%. Las imágenes diagnósticas reportaron una esofagogastroileítis, con evidencia microscópica de infiltración eosinofila en todas las muestras, por lo cual se diagnosticó gastroenteropatía eosinofílica iniciando manejo con dieta hipoalergénica y prednisona. Discusión: hasta 25% de los pacientes con síndrome hipereosinofílico puede tener infiltración gastrointestinal, por lo que la gastroenteropatía eosinofílica debe sospecharse en todo paciente con dolor abdominal y eosinofilia periférica, no obstante, esta última no siempre está presente, siendo necesario un diagnóstico histopatológico.
Hepatitis C crónica: aspectos clínicos, serológicos y de tratamiento en dos centros de atención en Bogotá, Colombia
Authors: Prieto Ortíz Jhon Edison , Sánchez Pardo Santiago , Rojas Díaz Ever Leonardo , Huertas Pacheco Sandra Judith
Published: July 2019

Introducción: el virus de la hepatitis C afecta a cerca de 170 millones de personas en el mundo. La organización mundial de la salud (OMS) estima una prevalencia mundial del 2%. La respuesta global al tratamiento en la era de la terapia dual para genotipo 1 es del orden de 40%. En Colombia hay datos limitados que confirmen un comportamiento similar y que describan las características clínicas de los pacientes con esta infección. Metodología: se revisaron retrospectivamente las historias clínicas de pacientes con diagnóstico de hepatitis C crónica que asistieron a consulta externa del servicio de Hepatología en la Clínica Universitaria Colombia y de la consulta externa del servicio de Hepatología de uno de los autores durante el periodo comprendido entre el 1 de enero del 2010 y el 30 de mayo de 2013, se describen las características clínicas, serológicas y de respuesta al tratamiento. Resultados: se evaluaron las historias clínicas de 163 pacientes, 62% mujeres y 38% hombres, con una edad promedio de 58,2 años. El principal factor de riesgo para la adquisición de la hepatitis C fue historia de transfusiones antes de 1992 en 62% de los pacientes. La decisión de iniciar tratamiento se tomó en 77 pacientes (47,2%) y en 86 (52,8%) no se inició por diferentes razones dentro de las cuales la edad avanzada y cirrosis avanzada suman más de 50%; otras razones para no iniciar el tratamiento fueron: enfermedad mínima (4,7%), enfermedad mínima más edad avanzada (10,5%), curación espontánea (14%), poca probabilidad de respuesta (3,3%) y otras (14%). De 62 pacientes de los que se contaba con información acerca de tratamientos previos o tratados recientemente 30,6% presentaron respuesta viral sostenida (RVS), 29,0% fueron clasificados como reincidentes o relapser, 8,1% como respondedores parciales, 19,4% no tuvieron respuesta y 12,9% suspendieron el tratamiento por intolerancia. Conclusiones: el antecedente más frecuente para la adquisición del VHC en el grupo de pacientes estudiado fue la historia de transfusiones antes de 1992 asociada con cirugía ginecológica. Cerca de la mitad de los pacientes se diagnostican tardíamente. Se muestra una mayor tendencia al tratamiento de la hepatitis con tasas de RVS similares a las encontradas en otras series. Este estudio abre puertas a la realización de otros que permitan definir de forma más amplia la prevalencia, factores de riesgo y variables de respuesta al tratamiento de esta entidad en nuestro país.
The concept of land use model in Lithuania – the tool for sustainable development
Authors: Gaudėšius Rimvydas
Published: July 2019

Urbanization process in the Republic of Lithuania has formed a strong visual, cultural and economic gap between rural and urban areas. Lithuanian villages face major social, cultural changes and economic difficulties, which result in increasing migration of people to cities and foreign countries. Everyone could self-realize only in a safe and comfortable environment. The right environment, in which persons feel safe and are able to realize their potential in activities, can be created by spatial planning. Lithuanian scientists talk much about problems in territorial planning, but no particular proposals are offered and state institutions do not take any measures in order to stop this chaotic urbanization. There are a lot of problems related with land usage, so it is very important to create the sustainable model of land usage in Lithuania.