bluuebunny/crossref_metadata_2025 huggingface dataset:
Disponibilidad léxica en niños en Partes del cuerpo y la alineación con estándares de aprendizaje de lenguas extranjeras
Authors: Martí Contreras Jorge
Published: February 2024

El presente artículo muestra un estudio de disponibilidad léxica en el que se han realizado un total de 420 encuestas a niños/as de 7, 9 y 11 años dentro del centro de interés “partes del cuerpo”. La investigación tiene dos grandes novedades, por un lado, el gran número de informantes que hace que los resultados sean significativos y, por otro lado, que los informantes son niños. Se ofrece la muestra clasificada por franjas etarias y por tipología de centro, se compara con los contenidos de obras que se consideran estándares de la enseñanza-aprendizaje de lenguas y se demuestra que existen grandes disonancias entre las propuestas de esas obras y la disponibilidad léxica real de niños de 7, 9 y 11 años. También se estudia la cohesión léxica según los rasgos de edad, sexo y centro de estudios. Se destaca que se debe tener en cuenta la madurez lingüística del alumnado para establecer el nivel adquisición de la lengua. La investigación sirve como punto de partida para poder integrar al estudiantado extranjero que no tiene conocimiento de la lengua meta y que se incorpora en un aula de infantil o de primaria una vez iniciado el curso.
Capitalizando la Querelle des femmes: Una oportunidad de negocio para sus editores
Authors: Aguilar González Juan
Published: February 2024

En los años de la Querelle des femmes el mercado editorial no fue ajeno al interés que despertaron las obras enmarcadas en esta disputa. Especialmente provechosas para las imprentas parecen haber sido las réplicas y contrarréplicas a los tratados misóginos y así lo atestigua el hecho de que se encuentren, en varias ocasiones, los nombres de los mismos editores, los cuales publicaron textos tanto a favor como en contra de las mujeres. Este trabajo mira a analizar tales ocasiones y a avanzar algunas hipótesis sobre su publicación bajo la óptica del interés comercial, en lugar del académico. Siendo tan vasta la cantidad de obras que vieron la luz en torno a este debate, circunscribimos nuestro análisis a la labor de unos pocos editores.
Defensionde delle donne by Agostino Strozzi. two mysterious manuscripts
Authors: Ramírez  Almazán María Dolores , Vargas Martínez Ana
Published: February 2024

Defensione delle donne, de Agostino Strozzi, es una de las obras filóginas más significativas en lengua italiana compuesta a finales del siglo XV. Nos consta la existencia de dos versiones recogidas en dos manuscritos que presentan contrastes significativos entre ambas. Una de ellas más extensa y, sobre todo, más radical en sus argumentos en defensa de las virtudes femeninas, está dedicada a su prima Margherita Cantelmo. En esta comunicación se describe y profundiza en los contrastes presentes en ambas versiones o, dicho con otras palabras, en lo que podemos considerar como dos misteriosos manuscritos.
Identification of saliva biomarkers as tools for detection of early-stage oral squamous cell carcinoma
Authors: Dawood Mohammad , Salim Khudeja , Khan Faisal
Published: February 2024

Cancer of the flat squamous cells of the oral cavity is called Oral Squamous Cancer Cell (OSCC). OSCC is responsible for 95% of all oral cancers. In high-risk countries like Pakistan, OSCC has one of the highest mortality rates amongst the general demographic. With most OSCC cases being identified in later stages, the 5-year survival rates have remained as low as 50%. However, with early diagnosis, OSCC patients have been shown to have a better chance of surviving. To that effect, identifying potential biomarkers to act as diagnostic indicators for OSCC can help in early diagnosis of the disease. An emerging field for alternative detection of cancer are non-invasive methods that use saliva as a fluid for liquid biopsies. Saliva comprises proteomes, microbiomes, metabolomes, transcriptomes, and genomes that can be used as potential tools for the early detection of cancer. “Salivaomics” has established itself as a promising area for diagnostic and prognostic purposes. In this review paper, we perform a meta-analysis and a systematic literature review to catalogue biomarkers found in saliva that could potentially be used in the early diagnosis of OSCC.
Ensaios interdisciplinares em tempos líquidos: Homenagem a Zygmunt Bauman – volume 4
Authors:   Hildeliza Boechat Cabral,   Juçara Gonçalves Lima Bedim,   Moyana Mariano Robles-Lessa
Published: February 2024

A leitura da obra Ensaios interdisciplinares em tempos líquidos: homenagem a Zygmunt Bauman – volume IV contribui para fazer eclodir a reflexão e a conscientização sobre o que Bauman ressalta ao dizer que o aspecto em que somos semelhantes é decididamente mais significativo que o que nos separa. Dizemos, então, que nossas diversidades e nossa humanidade nos flagram como metonímia humana, em que somos partes integrantes de um único todo. Nessa cena metonímica, podemos subverter o modelo mental e cultural que instaura a violência como representação de força e a emoção/afetividade como fraqueza. Podemos decidir e refazer nosso modelo cultural de relação interpessoal, reconstruindo conscientemente o Self autobiográfico de afetividade para atuar nas cenas sociais com respeito, amorosidade e valorização do outro na dinâmica interativa. Assim, a obra Ensaios interdisciplinares pode propulsionar reflexões que nos levem a práticas inclusivas construídas nas bases da cultura de Direitos Humanos. Podemos decifrar o enigma da modernidade líquida, criando laços de afetividade nas nossas relações sociais.
Severe Traumatic Brain Injury Induced Coagulopathy in Pediatric: An Important Lesson with Literature Review
Authors: Arifianto Muhammad Reza , Suryaningtyas Wihasto , Parenrengi Muhammad Arifin
Published: February 2024

Children with coagulopathy had a greater mortality rate after moderate to severe traumatic brain injury (TBI). The purpose of the current study was to examine the most recent relevant literature in relation to the therapy of TIC in pediatric isolated severe TBI patients. A 5 years old boy presented to emergency department with decrease of consciousness after hit by a motorcycle. He was referred from the district hospital without proper stabilization within 3 hours after the injury. From the blood examination, hemoglobin level was 8.1 g/dl, base deficit -9.9mEq/L with PTT and aPTT no coagulation suggesting coagulopathy. Emergency non-contrast head computed tomography was performed and showed anterior skull base fracture with discontinuity in left squamous suture suggesting a diastases fracture with an air hypodensity lesion in left frontal area suggesting a pneumocephalus. There was also a hyperdense lesion with crescent shape in frontal and interhemispheric region suggesting subdural hematoma. Delayed operation for almost 6 hours was advocated due to transfusion of whole blood and fresh frozen plasma to correct coagulopathy. The operation was successful, the patient was survived but upon 2 years follow up, the patient still wasn’t able to perform normal daily activity. Localized injury at the brain manifesting in systemic coagulopathy requires special care. Several steps need to be evaluated before surgery but it should not delay the attempt of controlling the source of coagulopathy by it means lesion in the brain. Our case demonstrates the important of recognizing and managing coagulopathy in severe traumatic brain injury.
Accuracy of Nasal House Dust Mite-Specific Immunoglobulin E in Diagnosis of Local Allergic Rhinitis
Authors: Rosalina Elsa , Reno Pawarti Dwi , Kristyono Irwan , Abdullah Baharudin
Published: February 2024

Background: Local allergic rhinitis (LAR) is the symptom of allergic rhinitis in which nasal allergen-specific immunoglobulin E(IgE) is detected but has no sensitivity to systemic allergens. The gold standard test is the nasal allergen provocation test (NAPT) which requires a complicated procedure. Specific IgE in nasal mucosa test is the less invasive and easier diagnostic alternative for LAR. Aims: This review aimed to determine the validity of the nasal house dust mite - specific IgE test for LAR patients. Study designs: A meta-analysis was conducted in chronic rhinitis patients with negative skin prick test (SPT) and serum IgE. Methods: The research was using PubMed Central, Cochrane library, SAGE journals, and Science Direct were searched until July 29th, 2022. The validity of the nasal HDM - specific IgE test was compared to NAPT. Results: A total of 413 research articles were selected and five articles were included. The QUADAS-2 assessment showed minimum publication bias. The total sample was 236 patients. Pooled sensitivity 90.00%, I2= 28.95% and p=0.01. Pooled specificity 96.00%, I2= 30.28% and p=0.00. The value of the area under the curve in the SROC curve = 0.9710, statistically significant. Conclusion: The nasal HDM- specific IgE test is valid for diagnosing patients with LAR.
Characteristic and Formulation Turmeric Extract Nanoemulsion as Alternative Moisturizer in Atopic Dermatitis
Authors: N Suryawati , IGAAE Indira , M Wardhana , IW Sumardika , AW Indrayani , DA Arimurni , L Chabib
Published: February 2024

Currently, many moisturizers are developed with anti-inflammatory ingredients intended for mild and moderate atopic dermatitis (AD). One of the ingredients that can be developed is turmeric (Curcuma longa), which has potent anti-inflammatory activity. However, turmeric topical treatments require nano formulas due to their limited skin absorption. This study aims to obtain the optimal formulation of turmeric extract nanoemulsion as an alternative moisturizer for AD. The nanoemulsions are made by a self-nanoemulsifying drug delivery system (SNEDDS) using a simplex lattice design (SLD). Based on the solubility test, the oil components were sunflower oil, tween 80 as a surfactant, and polyethylene glycol (PEG) 400 as cosurfactant with a ratio of 1:8:1. The SNEDDS formulation was analyzed using software design expert version 10.03. The optimum SNEDDS formulation characteristic included an average droplet size of 13.37nm, an average polydispersity index (PDI) of 0.179, an average transmittance of 81.53%, and an average zeta potential of -38.57mV. Based on these results, it can be concluded that the turmeric extract formula meets the nanoemulsion criteria because the average droplet size is <200nm, the droplet distribution is relatively homogeneous as illustrated by the small average PDI, the transmittancesare above 80%, and is relatively stable with a zeta potential >±30mV.
Correlation between Transforming Growth Factor-Beta Levels and Skin Disorder Levels based on Modified Rodnan’s Skin Scores in Systemic Sclerosis Patients
Authors: Novianty Zuhria , Tjandrawati Anna , Rostini Tiene , Prihatni Delita , Dewi Sumartini
Published: February 2024

Systemic sclerosis is a chronic connective tissue disease characterized by the excessive formation of fibrous tissue. The current determination of systemic sclerosis progression uses the modified Rodnan’s skin score (MRSS), which is checked manually by assessing skin stiffness based on subjective pinching. Transforming growth factor-beta (TGF-β) is a major cytokine in the formation of fibrous tissue as the potential marker of systemic sclerosis progression and the targeting therapy. This study aims to determine the correlation between TGF-β levels and modified Rodnan’s skin score in systemic sclerosis patients.This study was a cross-sectional design and carried out in September 2021 at RSUP Dr. Hasan Sadikin, Bandung. This research examined 33 samples of the biological material of systemic sclerosis patients obtained from a study entitled "Development of a Systemic Sclerosis Registry System Based on Electronic Medical Records" which were stored at -80 ºC. A TGF-β test was performed at the Clinical Laboratory of Hasan Sadikin General Hospital, Bandung.The results of this study showed that the mean TGF-β level was 19.6 + 4.7 ng/mL. We found a significant moderate correlation between TGF-β and modified Rodnan’s skin score with an R-value of 0.513 and a p-value of 0.002.In conclusion, there is a statistically significant moderate positive correlation between TGF-β levels and modified Rodnan’s skin scores in patients with systemic sclerosis. Although TGF-β is the main mediator of fibrous tissue formation, there are many other mediators.
The Implementation Mechanism, Application, And Development Prospects Of Turkey’s Drone Strategy
Authors: Kuang Ho Yeh
Published: February 2024

Drones possess precise intelligence gathering, casualty avoidance, and remote strikes as an emerging strategic technology. With the rapid development of functionality and application modes, drones have become a new focal point in international military competition. In recent years, the operational contributions of Turkish drones in multiple battles have attracted global attention. This article examines the background formation, implementation mechanisms, and further prospects of Turkey’s drone strategy to understand the complex factors behind the particular development patterns. This article adopts the analytic hierarchy process and draws on current literature and case studies, analyzing multiple perspectives of Turkey’s drone strategy from two hierarchical levels: domestic politics and international environments. As a latecomer, Turkey has made significant strategic achievements in the field of drones. The analysis of Turkey’s strategic planning and practices in domestic and international arenas in different periods hold a certain degree of reference for drone development both in China and in the international society.
The Impact of Medicare Annual Wellness Visit Education on Advance Care Planning in a Family Medicine Residency Training Program
Authors: Swamy Meghana
Published: February 2024

Learning Objectives:

- Understand the Significance of Annual Wellness Visits (AWVs) in ACP:
- Evaluate the Impact of Resident Education on ACP Documentation
- Consider implications of AWV education on patient centered care and future practices
Actuator Line Model for Wind Turbine Wake Prediction with PyFR
Authors: Liang Tianyang
Published: February 2024

Since the simulation of a large floating offshore wind turbines (FOWT) wind farm requires significant computational cost, it is important to develop an efficient and accurate numerical model to predict the horizontal axis wind turbine (HAWT) wake structure under complex situations. In this study, a numerical HAWT model based on the actuator line (AL) method and PyFR solver are proposed. In this model, the geometric models of the blades, nacelle, and tower are replaced by body force source terms, which can significantly reduce the computational cost. In addition, the flux reconstruction (FR) method is applied to obtain accurate wake characteristics with less mesh number. The result shows that the proposed AL-PyFR(N T) model requires only 0.26 million mesh number to achieve a more accurate prediction of the wake velocity and turbulent kinetic energy (TKE), compared to 34.15 million mesh number for the blade-resolved model and 13.5 million mesh number for the AL-IB-LES model. The significant reduction in computational cost enables the simulation of large offshore wind farms.
Del Metate al Multipractic: Régimen Alimenticio de la Forma-de-Vida en Santiago Yancuictlalpan, Cuetzalan
Authors: González Chaparro Karol
Published: February 2024

Este artículo es el primer avance de una investigación de maestría en curso en donde se explora la posibilidad de centrar el sujeto antropológico de la antropología de la alimentación en la forma-de-vida. Esta propuesta proviene del trabajo de campo realizado en Santiago Yancuictlalpan, Cuetzalan, México, durante tres meses y medio de estancia continua. Para realizar dicha propuesta se inicia con un breve recorrido histórico de las aproximaciones teóricas de la antropología de la alimentación, se sintetizan sus características y se construye –a partir de los vacíos conceptuales– el marco teórico que guía toda la investigación. Además, se realiza una breve etnografía del régimen alimenticio de la forma-de-vida en Santiago Yancuictlalpan y se discuten los resultados.
DEFORMED STATE’S SIMULATION OF THE FIRST-GRADE TITANIUM FOIL OF THE ACCELERATOR OUTPUT WINDOW
Authors: ISUNTS H.A. , DAVTYAN A.H. , AVAGYAN V.SH.
Published: February 2024

The output accelerator windows, particularly the used metal foils are studied. The work was carried out to assess the strength of the first-strength grade titanium foil and the choice of variable parameters of the thickness of the foil. Depending on the latter, the simulation was performed by the finite element analysis in the ABAQUS automated software environment. The distributions of displacements, plastic strains of concavity caused by pressure differences, and radial and circumferential stresses have been studied in the foil's static state for 10 metal foils with a thickness of 50…500 microns. The basic dimensions of the titanium metal film are introduced: thickness and diameter. Atmospheric pressure was applied as an external force of influence, and the vacuum pressure was assumed to be zero. The metal shells were divided into a large number of nodes, which ensured higher accuracy for simulations. As a result of simulation, curves of the displacements of the selected points of the metal foil in the direction of the Y axis, depending on the values of the radiuses, and the curves of the strains intensities distributions of the metal foil were built, which were also analyzed. The metal foil of the output window was investigated so that simulation results could be applied to both output windows: mechanical connection and diffusion connection.
IBIS MODEL ACCURACY IMPROVEMENT USING VARIABLE STEP
Authors: GHUKASYAN S.A. , VARDANYAN H.V. , PAPYAN E.T. , KARAPETYAN E.Y. , KHACHATRYAN R.N.
Published: February 2024

In all times of integrated circuits (IC) manufacturing, the speed of getting the product on the market has been the main problem for all manufacturers. The main reason for late products has always been the speed of the tools that carry out the testing. The main simulator used by every manufacturer is the SPICE simulator, but with the SPICE simulator it can take up to months to simulate the whole TXRX macro. But since the 1990s with the introduction of the I/O Buffer Information Specification (IBIS) models, the testing time has decreased dramatically.
A method is proposed to generate IBIS models with a variable step, that will help to increase the accuracy of the IBIS model during signal integrity (SI) simulations and will correlate with SPICE simulations better. The proposed method can be implemented for all types of TX drivers and IBIS models.
POWER SNIFFER PERFORMANCE DEGRADATION AND WAYS TO SUPPRESS THE DEVIATION OF THE WORKING PARAMETERS DUE TO RANDOM TECHNOLOGICAL VARIATIONS
Authors: GEVORGYAN V.S.
Published: February 2024

One of the most important challenges of modern ICs is power dissipation, particula-rly the static power dissipation. To be able to reduce static power consumption of an IC, it is separated into different power domains so that the supply power can be turned off for certain domain when not in use. Separate power domains lead to several peculiarities, one of them is the powering up and down the power supply. To represent the supply voltage state by another domain supply, circuits like power sniffers are used. With the evolution of the technologies, the role of random technological variations in the circuits becomes substantial. The paper presents ways to reduce the performance degradation caused by random variations in the 16nm technological process node. HSpice tool is used for circuit simulations. Target sigma representing random variations is 5. For every PVT 300 iterations with random variations are run. The results are presented by QQ plots and measurement table. By applying the proposed modifications performance degradation is reduced by around 40% (average for all measured parameters). By implementing the proposed circuit changes the area of the circuit is increasing by around 35%, no power consumption increase is observed.
Rezension von: Schimmelpfennig von der Oye, Marta, Skulptur und Stukkatur des Rokokos in Hohenzollern
Authors: Senn Ernst , Schimmelfennig von der Oye Marta
Published: February 2024

Marta Schimmelpfennig von der Oye: Skulptur und Stukkatur des Rokokos in Hohenzollern, Berlin : Elsner, 1936. 87 S.
Rezension von: Das Irma West-Kinderfest in Hechingen, 1936
Authors: Schäfer Josef
Published: February 2024

Das Irma West-Kinderfest in Hechingen, Beilage zu den „Hohenzollerischen Blättern", Nr. 164, vom 18.07.1936.
Rezension von: Baur, Willy, Die Stadt Sigmaringen
Authors: Walter M. , Baur Willy
Published: February 2024

Willy Baur: Die Stadt Sigmaringen. Landschaft, Geschichte, Kunstdenkmäler, Hechingen (Hohenzollern) : Holzinger, 1936. 33 Seiten : Ill., Kt.
Rezension von: Schilfgaarde, Antonie Paul, Het Archief van het Huis Bergh
Authors: Senn Ernst , Schilfgaarde Antonie Paul van
Published: February 2024

Antonie Paul van Schilfgaarde: Het Archief van het Huis Bergh, Nimwegen : N.V. Druckerei G.J. Thieme, 1932.
¿Por qué los universitarios no participan en clase?
Authors: Martinez Valera Pedro , Bouroncle Velásquez Mauricio
Published: February 2024

Hablar en público, interactuar con desconocidos, comunicarse con el sexo opuesto, expresar desagrado y sentir temor de hacer el ridículo, son situaciones muy comunes que originan ansiedad social en nuestros estudiantes universitarios. El objetivo de nuestra investigación, es determinar la relación existente, entre estos cinco componentes de la ansiedad social, con la ansiedad estado (eventos estresantes) y con la ansiedad rasgo (carga hereditaria o biológica). Para lograrlo, una muestra no aleatoria de 449 jóvenes de ambos sexos, estudiantes de pregrado de las carreras de psicología y derecho de una universidad privada de Lima Sur, participaron de una encuesta en línea, respondiendo dos instrumentos validados en nuestro país: El Inventario de Ansiedad Rasgo-Estado (IDARE) y el Cuestionario de Ansiedad Social para Adultos (CASO– A30).
Importance and Relevance of the Brazilian Journal of Transplantation for Brazilian Transplantation
Authors: Boin Ilka de Fatima Santana Ferreira , Haddad Luciana , Ferreira Gustavo Fernandes
Published: February 2024

The Brazilian Journal of Transplantation, through its activities and commitment to high ethical and academic standards, aims to consolidate itself as a reference in the dissemination of knowledge and scientific advancement in the field of transplants, both nationally and internationally. BJT's social contribution as a reliable and peer-reviewed dissemination vehicle is undeniable. It reaches the scientific community and the population in general, demystifying the organ donation processes, highlighting the organ distribution model through the national single queue and raising awareness of the need for donation
Dalla politica statale alle costituzioni sociali globali
Authors: Přibáň Jiří
Published: February 2024

Il contributo intende offrire una rilettura critica dell’ultima monografia di Francesca Scamardella, Etsi Constitutio non daretur. Le costituzioni civili nel mondo transnazionale (2023). Il libro prova ad esplorare la categoria del ‘costituzionalismo sociale’ che tra i suoi principali e contemporanei interpreti annovera Gunther Teubner. Tuttavia, non si tratta di una semplice ri-proposizione della teoria del sociologo tedesco, perché l’autrice inscrive la nuova “questione costituzionale” nell’attuale contesto sociale, politico e giuridico, caratterizzato da un polisemico pluralismo giuridico. Invocando una governance costituzionale di tipo transnazionale, il costituzionalismo post-weimariano si dota dell’elemento riflessivo e di quello funzionale. Questo ci conduce ad immaginare una normatività costituzionale che limiterebbe il potere espansionistico dei sottosistemi sociali, piuttosto che organizzare il potere politico, come hanno fatto le Costituzioni tradizionali.
Gymnanthemum amygdalinum: an addition to the Asteraceous Flora of Uttar Pradesh, India
Authors: Gupta Preeti , Madhukar Virendra , Shekhar Shweta
Published: February 2024

In the present paper, the occurrence of Gymnanthemum amygdalinum (Delile) Sch.Bip. in Uttar Pradesh, is being reported first time for the flora of Uttar Pradesh. A brief description with updated nomenclature, locality and photographs have been provided.
O uso do sistema de informação em saúde: avanços e dificuldades no funcionamento do sistema e-SUS na UBS malhada
Authors: Barbosa Coelho Marciana , Sousa Gustavo Barbosa de , Paiva Luis Eduardo Brandão , Araújo Rafaela de Almeida
Published: February 2024

O sistema de informação da atenção básica e-SUS AB é um sistema que veio para garantir uma melhor qualidade nas informações em saúde, com o uso de ferramentas que proporcionam um melhor acompanhamento tantos dos profissionais da saúde como da gestão. É nesse sentido que a pesquisa aqui delineada teve por objetivo analisar os avanços e as principais dificuldades encontradas no funcionamento do sistema e-SUS na perspectiva dos funcionários da Unidade Básica de Saúde Malhada. A modalidade de pesquisa adotada para este trabalho foi uma pesquisa qualitativa de natureza descritiva, com entrevistas semiestruturada, a análise dos dados foi realizada por meio de análise de conteúdo (BARDIN, 2011). Como resultados a pesquisa pode concluir que o e-SUS AB que vem facilitando aos profissionais no atendimento à população, como também na organização dos dados dos pacientes sendo acompanhado pelo Ministério da Saúde em tempo real.
Views of generation Z nurse candidates on their willingness to work in featured services in hospitals: A qualitative study
Authors: Cetin Yasin , Ozen Asli , Savas Mumin
Published: February 2024

The aim of this study is to identify the willingness of generation Z nursing students to work in the specialized units, as well as their views about these units, and to find answers to issues such as which units they want to work in and why. In this study, the phenomenological design of the qualitative research method was used. The purposive sampling technique was preferred in the sample selection of the study. The sample consisted of 16 students who completed their internal medicine nursing course and continued their education in the second year at Adiyaman University Faculty of Health Sciences. A semi-structured 13-item interview form was used as a data collection tool. The content analysis technique was used to analyze the data. Following the analysis, seven sub-themes were obtained. In the study, seven sub-themes were determined including explaining the reasons for specialized units, willingness to work in specialized units, choosing a particular specialized unit, getting support in deciding on the specialized units, the contribution of nursing education to deciding on the specialized units, research for specialized units, and physical opportunities in the specialized units. In accordance with the determined sub-themes, it was concluded that Z-generation nursing students desired to work in specialized units due to their professional development, improved patient care, more economic income, less violence towards healthcare workers in these units, as well as being informed by the lecturers, and sufficient physical opportunities.
Retrospective evaluation of cases of benign transient hyperphosphatasemia
Authors: Ozer Yavuz
Published: February 2024

This study aimed to evaluate the demographic, clinical, and laboratory characteristics of children with benign transient hyperphosphatasemia (BTH) and to increase awareness of BTH. Children with BTH followed up in a tertiary pediatric endocrinology outpatient clinic were included in this retrospective study. Children who were aged under 5 years, who had no evidence of liver, kidney, or bone disease, who had serum total alkaline phosphatase (ALP) levels above 1000 IU/L, and whose ALP values resolved within 4 months, were included in the study. The study included 10 infants and children (4 females) with BTH who were referred to our clinic during 1 year for high ALP levels. The mean age was 2.4±0.5 years. The mean weight SDS was -0.24±1.27 and the mean height SDS was -0.51±0.67. The mean ALP level was 2.395±934 IU/L. The mean normalization time for serum ALP was 2.4±1.1 months. Benign transient hyperphosphatasemia is an entity that occurs in healthy infants and children without evidence of liver or bone disease and resolves without intervention.
Study on psychological well-being and its determinants among elderly people attending geriatric clinic at Medical College, Kolkata
Authors: Manna Nirmalya , Das Pushpak , Reja Abhishek , Das Pratibha , Talukdar Arunansu
Published: February 2024

Background: Significant growth in the proportion of older people in India will lead to changes in the country’s society. If common psychological problems such as depression and anxiety are not addressed, they can have lasting effects on individuals, particularly older individuals. It has the potential to impair the management of ongoing chronic illnesses and result in both physical and mental limitations.

Aims and Objectives: The objective was to assess the psychological well-being (PWB) of the study participants attending the geriatric outpatient department and its contributing factor(s).

Materials and Methods: A descriptive, cross-sectional, hospital-based study was conducted in the Geriatric Clinic of Medical College, Kolkata, among 301 geriatric people during a 1-year time period. The assessment of PWB was done using Ryff’s PWB scales, 42-item version. The analysis of the data was done using SPSS version 16.

Results: The mean age of the participants was 66.68 (±6.48) years. The mean PWB score was 156.2 ± 18.6 according to Ryff’s PWB scales. The minimum score was 94, and the maximum score was 226. Poor PWB was seen among 50.8% of the elderly.

Conclusion: Poor PWB among seniors and several factors such as current living arrangements, socioeconomic status, employment history, history of recent injury, and patients’ spiritual history play an important role. To handle the issue, new and modified geriatric health policies are very much needed.
RAPD-markers assisted genetic diversity analysis and Bt-Cry1Ac gene identification in eggplant (Solanum melongena L.)
Authors: Hasan Rokibul , Rahman Md , Kabir Ahmad , Haydar F , Reza Md
Published: February 2024

Generic diversity (GD) screening helps to identify candidate genes involved in diseases, pests, or other stress resistance in plants. GD is crucial for maintaining vigor and healthy plant population. The random amplified polymorphic DNA (RAPD) is a rapid polymerase chain reaction (PCR)-based molecular marker, effective for screening genetic diversity in diverse plant species. In this study, we applied the RAPD-markers-assisted PCR approach to explore genetic diversity (GD) among 7 varieties of eggplant (Solanum melongena L.) at DNA level. Further, we assessed the presence of Bt-Cry1Ac gene in those varieties using the PCR approach. The eggplants showed genetic diversity at the DNA level. The amplification with two RAPD primers (OPA-02, OPA-04) produced a total of 41 bands. The highest similarity showed 78.57% among sample 4 (Eggplant China) vs sample 7 (Purple king F1) and sample 1 (Eggplant Srilanka) vs sample 4 (Eggplant China), while the lowest was 28.57% among sample 7 (Purple king F1) vs sample 3 (Eggplant Chittagong-1). In addition, the PCR results for the Bt Cry1Ac primer did not show a considerable band in the expected amplicon size. The dendrogram showed the genetic variability and relationship among all seven eggplant varieties at the genetic level. The study formulated a simple marker-based method for an effective molecular protocol to study genetics in eggplants. It also reported the presence of the Bt gene in popular eggplant varieties.
Potentials of phytotherapy on microRNAs in chronic kidney diseases
Authors: Moni Akhi , Uddin Md
Published: February 2024

Chronic kidney diseases (CKD) describe the loss of renal function and/or abnormal structure. CKD is linked with inflammation, oxidative stress, fibrosis, autophagy dysfunction, and mitochondrial dysfunction [1]. Currently, treatment focuses on the management of symptoms, which emphasis the need of novel therapeutic options [2]. On the other hand, dysregulation of specific microRNA (miRNA) is associated with abnormal kidney function, rendering them important targets for treating CKD. The roots, leaves, stems and various bioactive compounds of herbal plants appear as a potential candidate for CKD therapy [3]. Thus, the current study emphasizes the phytotherapy that alters the miRNAs that are associated with CKD, focused their mechanisms and therapeutic avenues.
6 ŞUBAT 2023 KAHRAMANMARAŞ DEPREMLERİNİN DIŞ TİCARET ÜZERİNDEKİ ETKİLERİ: 11 İL ÖRNEĞİ
Authors: ÖZSALMAN Emre , YILDIRIM Umut Turgut
Published: February 2024

Bu çalışmanın amacı, 6 Şubat 2023 tarihinde Kahramanmaraş’ta meydana gelen depremlerin Türkiye’nin ithalat/ihracatı üzerindeki etkilerini ciddi zarar gören 11 il üzerinden analiz etmektir. Çalışma, depremden etkilenen iller özelinde bir analiz yapması, aktüel bir olaya eğilmesi ve deprem sonrasında illerin dış ticaretinde meydana gelen değişimlerin sebeplerine ilişkin değerlendirme yapmasıyla literatürden ayrılmaktadır. Çalışmada hem doğal afet-dış ticaret ilişkisi genel manasıyla hem de depremlerin dış ticaret üzerindeki etkileri Türkiye özelinde birlikte ele alınmaktadır. Türkiye üzerine yapılan analiz, depremlerin etkilerinin yoğun olarak hissedildiği ilk 6 aylık şok periyodunu kapsamaktadır. Bu dönemde 11 ilin depremler sonrasındaki dış ticaret verileri karşılaştırmalı olarak ve sektör bazında incelenmektedir. Çalışmanın verileri İçişleri Bakanlığı Afet ve Acil Durum Yönetimi Başkanlığı (AFAD), Devlet Planlama Teşkilatı (DPT), Türkiye İhracatçılar Meclisi (TİM) raporları ve Türkiye İstatistik Kurumunun (TÜİK) veri setlerinden derlenmiş ve çalışmada nitel araştırma yöntemleri benimsemiştir. İncelenen 11 ilin şubat ayı ihracat rakamlarında Diyarbakır hariç diğer bütün illerde sert düşüş yaşandığı; Adıyaman ve Diyarbakır illeri haricindeki diğer 9 ilde de ithalat rakamlarının radikal biçimde düştüğü tespit edilmiştir. Bir önceki yılın ocak-ağustos dönemi ile karşılaştırıldığında 11 ilin toplam ihracat ve ithalatında dramatik bir daralma yaşandığının tespit edilmesi de depremin kısa vadedeki etkilerini ortaya koymaktadır.
ANALYSIS OF THE WATER QUALITY INDEX (AQI) OF THE RESERVOIR CACHOEIRA I, A MEMBER OF THE AGRESTE BRANCH IN PERNAMBUCO
Authors: De Araújo Jônatas Santos , Marques Érika Alves Tavares , De Oliveira Cláudia Ricardo , Caldas Hidaiane Fayga Matias , Sobral Maria do Carmo Martins
Published: February 2024

The Agreste region of Pernambuco has a long history of water scarcity, with irregular rainfall and a semi-arid climate characterized by high solar radiation. In order to mitigate these effects in the region, the São Francisco River Integration Project is considered the largest infrastructure project in the country, bringing water to the most water-scarce areas. The Agreste Branch is part of this infrastructure project, with a length of 71 km, aiming to supply rivers and reservoirs in the state of Pernambuco. To ensure that the waters of the São Francisco River are reaching the region in good quality, the Water Quality Monitoring Program has been evaluating parameters at various points in the system, including local rivers and reservoirs. The Cachoeira I reservoir is a significant supply source in the municipality of Sertânia that is included in the monitoring program. This present study aims to assess the water quality of the Cachoeira I reservoir through the analysis of the Water Quality Index (WQI) and Trophic State Index (TSI). Through the analysis of these indices, an overall improvement in the classification of WQI and TSI was observed during the data collection period from 2018 to 2022, encompassing 12 monitoring campaigns, coinciding with the increase in water volume in the reservoir over the years. Understanding these parameters is crucial for the water management entities to make informed decisions in order to consistently improve the parameters and ensure the distribution of quality water to the population.
FLUORIDATION AND DISPOSAL OF PUBLIC WATER SUPPLY IN THE MARANHÃO AMAZON
Authors: Dos Santos Pedro Henrique Barros , Moimaz Suzely Adas Saliba , Saliba Orlando , Saliba Nemre Adas
Published: February 2024

Objective: to investigate access and fluoridation of public water supplies in the state of Maranhão. Method: descriptive, direct documentary research, carried out in governmental databases in 2022, also on-site surveys involving 23 municipalities in Maranhão Amazon belonging to the health macro-region IV. The investigated aspects were: population supplied by water; raw water sources; responsible body; water fluoridation and data availability. Only 38% of the population in the macro-region have access to piped water, of which only 44% is treated, the service performed by the state company and those managed by the municipal body were equivalent (48%). 484 sources of collection were identified, 99% underground supplying 92% of the population, this dependence on groundwater reaches 63% throughout the state, surface collection occurs only in the main municipality (5%). Despite the index that 91% of indicator 6.1.1 of the SDGs, the high rural population and the low demographic density constitute a challenge for the expansion of access. No municipality performs artificial fluoridation and there are no records of fluoride levels or previous analyses. There is a direct relationship between a lower HDI and access to potable water. Conclusion: a small part of the population has access to treated water, therefore fluoridation is not guaranteed and the surveillance system needs to be improved.
Tổng quan các loài nấm gây bệnh thuộc chi Ceratocystis Ellis & Halst (1980)
Authors: Chí Nguyễn Minh , Thu Phạm Quang
Published: February 2024

Bệnh loét và héo do nấm Ceratocystis gây thiệt hại kinh tế nghiêm trọng ở nhiều quốc gia và vùng lãnh thổ. Nghiên cứu này nhằm tổng hợp các kết quả nghiên cứu về bệnh do nấm Ceratocystis và cung cấp thông tin bao quát phục vụ quản lý bệnh hại. Các nghiên cứu đã ghi nhận 80 loài thuộc chi Ceratocystis là mầm bệnh của hơn 70 loài cây trồng thuộc 50 chi thực vật. Một số loài nấm là mầm bệnh trên nhiều loài cây chủ, trong đó nhóm loài trồng nông nghiệp: 4 loài, nhóm loài cây ăn quả: 7 loài, nhóm loài cây trồng lâm nghiệp: 74 loài và cây trồng khác: 10 loài. Nhiều loài cây lâm nghiệp đã bị nấm Ceratocystis gây hại, tập trung nhiều nhất ở các loài keo, bạch đàn và thông. Ngoài ra, một số loài côn trùng có thể vô tình lây truyền bệnh do nấm Ceratocystis. Các mầm bệnh này rất nguy hiểm, một số đã xâm nhiễm và gây hại trên diện rộng đối với các loài cây trồng chủ lực ở nhiều nơi. Khả năng lây lan của các mầm bệnh này rất nhanh, cả về diện tích và cây chủ. Những dữ liệu này sẽ góp phần quản lý hiệu quả bệnh loét, héo trong sản xuất nông lâm nghiệp. Ngoài ra, cần giám sát liên tục và có các nghiên cứu chuyên sâu về phòng trừ các mầm bệnh này.
Ruling the Dutch Tax Haven: How the United States Drove the Rise and Fall of the Ruling Practice of the Netherlands
Authors: Stadig Diederik
Published: February 2024

Ruling the Dutch Tax Haven: How the United States Drove the Rise and Fall of the Ruling Practice of the Netherlands

Until recently, the Netherlands was one of the world’s largest tax havens. A key factor in the country’s fiscal appeal was its ruling practice, which was created as a result of the Marshall aid in 1945. The ruling practice has remained mostly stable since its foundation: it underwent incremental reforms in the 1990s and 2000s, but radical reforms in the 2010s. This article seeks to explain this stability and radical change. To do so, it turns to theories on the role of ideas and institutional path dependence. It finds that the tolerance of the US for aggressive tax policies by small states was an important precondition for the stability of the Dutch ruling practice. When this tolerance disappeared in the 2010s, the Netherlands was forced to reform its ruling practice. Thus, the agency of political actors may be overestimated and the structuring role of institutions and the international context downplayed.
The working mechanisms of the victim-offender mediation process: how might participation explain psychological outcomes in offenders?
Authors: Jonas-van Dijk Jiska , Zebel Sven , Claessen Jacques , Nelen Hans
Published: February 2024

The working mechanisms of the victim-offender mediation process: how might participation explain psychological outcomes in offenders?

Previous research shows that participation in victim-offender mediation (VOM) predicts psychological outcomes in offenders – such as increased responsibility-taking and victim empathy. However, little is known about elements that might contribute to these outcomes. We hypothesised that adhering to three fundamental conditions of VOM (perceived voluntary participation, preparation, professional competencies of mediators) and three working mechanisms (learning opportunity, humanising impact, a positive and constructive atmosphere and interaction with victims) would relate positively to the occurrence of these outcomes. In addition, we expected the fundamental conditions to either moderate the association between the working mechanisms and the psychological outcomes or to directly predict the presence of the working mechanisms. To examine this, we used quantitative (n = 55) and qualitative data (n = 9) of offenders and mediators, respectively, who participated in VOM. Results offered partial support for the hypotheses. Three groups of working mechanisms of the VOM process were related to psychological outcome variables: the perceived degree of a positive and constructive atmosphere and interaction with victims, humanising impact, and offering a learning process. The prevalence of the fundamental conditions, preparation and mediators’ professional competencies correlated positively with multiple working mechanisms; the perceived voluntary participation showed expected and unexpected associations with working mechanisms.
Affectivity in distance education
Authors: Fernandes Allysson Barbosa , Da Silva Claudia Kreuzberg , Guimarães Christiane Diniz , Rodrigues Isabela de Melo , Klauch Jorge José , De Souza Juliana Lima , Holanda Maria Gneglauda , Martins Paula Welliana Araujo
Published: February 2024

This article sought to deepen the understanding of the influence of affectivity in Distance Education (DE), exploring the intersection between this dimension, Contemporary Pedagogical Theories, and Educational Technologies. The main objective was to analyze how these elements converge to shape the student's experience in the DE modality, aiming to provide valuable insights for more effective and student-centered educational practices. The topic was succinctly addressed, divided into specific sections to explore crucial nuances. The theoretical framework encompasses Educational Psychology, Contemporary Pedagogical Theories, and the potential of Educational Technologies, providing a solid theoretical foundation. In the methodology, a bibliographic approach was chosen, conducting a critical review of specialized literature. The careful selection and analysis of relevant sources allowed for a holistic understanding of the topics, providing the construction of well-founded arguments. The results indicate the importance of strategically integrating affectivity, Contemporary Pedagogical Theories, and Educational Technologies in DE. The analysis highlights tools such as discussion forums, personalized feedback, and adaptive platforms as valuable instruments to strengthen the affective dimension and promote a more humane and effective learning experience. The conclusion not only summarizes the main results but also emphasizes the practical relevance of these findings in the context of DE, offering suggestions for future research and educational innovations. This study contributes to the continuous understanding and improvement of DE, considering the complex interactions between affectivity, pedagogical theories, and educational technologies.
Plan for innovation and educational technologies: a bibliographic analysis of the connected education innovation program
Authors: De Sousa Joana Darck Moreira , Lima Luziana da Silva , Vasconcelos Francisco Herbert Lima , Menezes Daniel Brandão , Ribeiro Ana Paula de Medeiros , Coutinho Emanuel Ferreira
Published: February 2024

The use of digital technologies in education is clearly expanding, a fact observed in the government's concern to create public policies in this area. This present have aims to report on the Connected Innovation Program. As a methodology, a bibliographical review was chosen, which is a way to collect documentary data about the program under study. The bibliographic survey was carried out in the Ministry of Education database and on the program's website. Considering the emerging context of society marked by the passage of a pandemic, the need to implement digital resources as well as empower teachers to fully use the tools, the public authorities are concerned about bringing possibilities for advancement in education supported by technological development. Today's traditional ways of teaching no longer have meaning for a generation plugged into social networks, specialists in entertainment games, followers of influential personalities on the internet. The Connected Innovation Program arises from this reality and seeks to support teachers and students in the saga of innovative teaching and meaningful learning.
The importance of people management policies: study at a university
Authors: Maduro Márcia Ribeiro , Bittencourt Maryângela Aguiar , De Lima Orlem Pinheiro , De Araújo Paulo César Diniz , Simões Aderli Vasconcelos
Published: February 2024

The general view of People Management in the public sector has special characteristics, as policies in the area have been implemented in a way that brings into context the many theories and trends in Administration and organizations in general. The general objective is to present the importance of implementing people management policies in the context from an Institution of the State of Amazonas; show that this knowledge contributes to strengthening institution management. Furthermore, it should be noted that it is essential to develop people management policies to provide parameters for investment in personnel within the university. The research was qualitative, exploratory and through a case study, originating from a bibliographic survey. The objective as a result is to contribute to implementing actions that bring about changes, in a sustainable way, seeking to meet the organizational, professional and personal development perspectives of employees.
Analysis of a portfolio selection model at three-moments
Authors: Martins Patricia Reis , Da Silva Patrícia Nunes , Vasconcellos Carlos Frederico , Lanzillotti Regina Serrão
Published: February 2024

This work performs a numerical simulation for an investment portfolio selection model that considers the three first moments of asset returns distribution – mean return, variance, and skewness. The application of the model, based on data collected on the platform of a Brazilian stockbroker, allowed obtaining portfolios of maximum skewness for fixed values of expected return and weighted variance of the portfolio. The results are analyzed and presented graphically, giving rise to an optimal surface for triples of moments associated with portfolios of maximum skewness. Furthermore, this experiment allowed us to confirm the relevance of considering higher-order moments in the selection of investment portfolios and verifying the efficiency of the Three-Moments model, having as reference the Markowitz solution in his Mean-Variance model.