bluuebunny/crossref_metadata_2025 huggingface dataset:
تأثير مستخلصات بعض النباتات الطبية في إنبات وقوة البادرة لمحصول البرسيم Trifolium alexandreum L
Authors: Abdullhussein Taif M. , Al- Hasnawy Riyadh A. , AL-Selawy Razaq L . , Kashkool Haider R. , Alkanany Ahmad A. , Muhamed Mustafa
Published: June 2023

نفذت تجربة مختبرية في مختبرات كلية الزراعة /جامعة كربلاء خلال العام 2015 بهدف تأثير المستخلصات المائية للنباتات الطبية في انبات وقوة البادرة لمحصول البرسيم وتحديد أفضل مستخلص نباتي. استخدم التصميم العشوائي الكامل CRD بثلاث مكررات وعامل واحد المستخلصات المائية T1) المقارنة= ماء مقطرو=T2 الحلبة وT3= الحبة الحلوة وT4= الحبة السوداء  وT5=الكمون).اظهرت النتائج ان معاملة  المستخلص T5 أدت الى زيادة معنوية في النسبة المئوية للإنبات بلغت 98.33% و طول الرويشة بلغت 4.21 ملغم والوزن الجاف للرويشة بلغ 22.70 ملغم .بينما أعطت المعاملتان T5وT4 اعلى سرعة انبات بلغت 5.03 بذرة.اليوم-1 و4.75 بذرة.اليوم-1 واعلى قوة بادرة بلغت 23.28 و21.88 و اعلى طول جذير بلغ 1.61سم و1.47 سم واعلى وزن جاف للجذير بلغ 8.13 ملغم و7.85 ملغم على التتابع في حين أعطت معاملة  المقارنةT1 اقل متوسط لنسبة المئوية للإنبات و سرعة الانبات وقوة البادرة وطول الجذير وطول الرويشة والوزن الجاف للجذير والوزن الجاف للرويشة بلغت 92.33% و4.61 بذرة.اليوم-1و20.81 و1.22 سم و5.60 سم و 3.45 ملغم و21.40 ملغم . أدت المستخلصات T2 وT3 الى تثبيط كل الصفات.
تأثير المعاملة بأنزيم ترانس كلوتامنيز على بعض الخصائص الريولوجية لطحين الحنطة العراقية -صنف الرشيد
Authors: Ramadhan Hussein Jaafer , Nasir Jassim M.
Published: June 2023

اجريت الدراسة الحالية للتحقق من إمكانية تحسين الخواص الكيميائية والريولوجية لعجينة طحين الحنطة العراقية (صنف الرشيد) وذلك بإضافة أنزيم ترانس كلوتامينيز البكتيري. كان الطحين المستخدم في البحث ضعيف النوعية، وان زمن نضج وثبات العجينة منخفضان، واللزوجة القصوى له مرتفعة عن الحد الطبيعي للطحين الصالح لصناعة الخبز، كما أن مقاومة المطاطية والمطاطية ومساحة المنحنى ونسبة البروتين كانت منخفضة أيضا". تمت معاملة الطحين المستخدم بتراكيز مختلفة من أنزيم ترانس كلوتامينيز (10 ، 30 ، 50 ، 100 ،150 وحدة / 100 غم طحين ) . كان التركيز 30 وحدة / 100 غم طحين هو الأفضل معنويا، فقد أعطى أعلى مقاومة للمطاطية ومساحة منحنى ومقاومة قصوى مقارنة مع معاملة السيطرة وبقية المعاملات ، كما أظهرت المعاملة 50 وحدة / 100 غم طحين زيادة معنوية في كل من محتوى الكلوتين الجاف والكلوتين الرطب (القوي). أظهرت نتائج معاملة الطحين بتراكيز مختلفة من الأنزيم ارتفاع معنوي في مؤشر الكلوتين ولكل المعاملات.
الفاعلية الحيوية لبعض المستخلصات الطبيعية في حياتية مـﱠن الباقلاء الاسود Aphis fabae ( Scop). Aphidadae : Homptera
Authors: AL-Musaifer Mohsen
Published: June 2023

أجريت دراسة حقلية ومختبرية لأختبار كفاءة المستخلص الايثانولي لنبات البابونجMatricaria chamomilla  وصمغ النحل (  (Propolisفي الاداء الحياتي لحشرة ﻤﱠن الباقلاء الأسود، حيث أظهرت الدراسة تفوق صمغ النحل في منع الفقس وهلاك الحوريات والبالغات بمعدل تراكمي بلغ (37.46 ، 70,24 ، 62.45 ) % على التوالي . في حين أنخفض تاثير البابونج في منع الفقس وهلاك الحوريات والبالغات بمعدل تراكمي بلغ ( 60.22 ، 45.51 ، 52.72 ) % على التوالي .

     كما اوضحت الدراسة وجود تفوق معنوي للتركيز 3% لصمغ النحل في منع الفقس والمعدل التراكمي لهلاك الحوريات والبالغات بلغ ( 10.0 ، 100.0 ، 97.70 ) % على التوالي . في حين كان للتركيز 3% للبابونج أقل تاثير في منع الفقس والمعدل التراكمي لهلاك الحوريات والبالغات بلغ ( 31.06 ، 77.73 ، 77.73 ) % على التوالي .مقارنة مع معاملة السيطرة والتي بلغ فيها معدل منع الفقس وهلاك الحوريات والبالغات ( 96.63 ، 3.3 ، 3.3 ) % على التوالي .

     كما بينت الدراسة زيادة التاثير بزيادة الفترة الزمنية فكان لليوم الثالث بعد المعاملة للبابونج دورا واضحا في منع الفقس وهلاك الحوريات والبالغات بمعدل تراكمي بلغ ( 54.12 ، 49.12 ، 57.45 ) % على التوالي . في حين أعطت الفترة الزمنية نفسها لصمغ النحل أفضل تاثير في منع الفقس وهلاك الحوريات والبالغات بمعدل تراكمي بلغ ( 30.80 ، 74.12 ، 67.45 )% على التوالي . مقارنة مع معاملة السيطرة حيث أعطت معدلا تراكميا بلغ ( 100.0 ، 3.3 ، 3.3 ) % على التوالي .
Clinical Isolation and Molecular Diagnosis of Cutaneous Leishmaniasis by using KDNA Gene PCR at some Baghdad Hospitals
Authors: Noori Nada , AL-Thwani Amina N. , AL.Aboody Basaad Akrab
Published: June 2023

تهدف هذه الدراسة إلى معرفة أكثر العينات سريرية وطرق التشخيص في داء الليشمانيات الجلدي المزمن (CCL). تم أخذ عينات من اللطاخة ، سائل الشفط ، وفلتر الورق ، من 44 آفة جلدية من الحالات المشتبه فيها بالـ CCL في بعض مستشفيات بغداد ، وتمت مقارنتها باستخدام الفحص المجهري ، والثقافة ، والأساليب الجزيئية. تم فحص عينات من المرضى الإكلينيكيين الذين أظهروا الخلع. PCR 95.45٪ (42/44)، والفحص المجهري 72.7٪ (32/44)، والثقافة 27٪ (12/44). وخلال الدراسة، المنتجات في KDNA -PCR، L.tropica و L. الكبرىمراقبة العصابات المتوقعة 780 و 650 نقطة أساس ، وورقة الترشيح العينات السريرية الأكثر فعالية من الآفة. وفي الختام ، فإن فحوصات PCR المستندة إلى اختبارنا على زيادة سرعة وحساسية تشخيص الحمض النووي الريبي النووي مهم جداً لتحديد الأنواع ( L. tropica و L. major ).
تأثير حامض الجبرليك والبنزايل أدنين وفترة التعرض للموجات الصوتية فوق السمعية في إنبات البذور ونمو شتلات شجرة الغاف (Prosopis cineraria L.) .
Authors: Shareef Sabah Gazi , Alkeliby Chaseb Khazaal Jawad , Alsafar Iman Mohammad Abbas , Hamzah Roaa Mahdi
Published: June 2023

نفذت التجربة وفق تصميم القطاعات العشوائية الكاملة خلال الفترة من نهاية شهر نيسان 2016 ولغاية أذار 2017 في كلية الزراعة / جامعة كربلاء ، لدراسة تأثير محلول حامض الجبرليك بتركيز (0 و150 و300 ملغم . لتر-1) ومحلول حامض البنزايل أدنين بتركيز (0 و 50و100 ملغم . لتر-1) وفترة التعرض للموجات الصوتية فوق السمعية لمدة (0 و 120 دقيقة) في انبات البذور ونمو شتلات الغافProsopis cineraria L.  . أظهرت النتائج تفوق معاملة محلول حامض الجبرليك (300 ملغم . لتر-1) معنوياً في جميع الصفات المدروسة قياساً إلى معاملة المقارنة وقد سجلت نسبة زيادة في انبات البذور بلغت 41.74 % عن معاملة المقارنة وتفوق معاملة محلول حامض البنزايل أدنين بتركيز (100 ملغم . لتر-1) معنوياً في جميع الصفات المدروسة عدا المحتوى الرطوبي النسبي ، في حين تفوقت معاملة التعرض للموجات الصوتية فوق السمعية لمدة (120 دقيقة) معنوياً في نسبة الانبات وقطر الساق ومحتوى أوراق الغاف من الكلوروفيل الكلي عن معاملة المقارنة وبنسبة زيادة بلغت على التوالي 26.01 و 12.91 و 28.94 % . تفوقت معاملة التداخل الثنائي بين حامض الجبرليك تركيز (300 ملغم . لتر-1) وحامض البنزايل أدنين تركيز (100 ملغم . لتر-1) في جميع الصفات المدروسة قياساً الى معاملة المقارنة ، في حين تفوقت معاملة التداخل الثنائي بين محلول حامض الجبرليك تركيز (300 ملغم . لتر-1) وفترة التعرض لشدة الموجات الصوتية فوق السمعية لمدة (120 دقيقة) في جميع الصفات المدروسة ما عدا صفة ارتفاع الشتلات وقطر الساق قياساً بمعاملة المقارنة . أظهرت نتائج التداخل الثلاثي بين حامض الجبرليك تركيز (300 ملغم . لتر-1) وحامض البنزايل أدنين تركيز(100 ملغم . لتر-1) وفترة التعرض للموجات الصوتية فوق السمعية لمدة (120 دقيقة) أعلى معدل معنوي في جميع الصفات المدروسة ما عدا المحتوى الرطوبي النسبي للأوراق قياساً إلى معاملة المقارنة وسجلت أعلى نسبة انبات في البذور بلغت 73.33 % قياساً إلى معاملة المقارنة التي أعطت أقل معدل بلغ 20.00 % .
Gobierno corporativo y buenas prácticas para las organizaciones sin fines de lucro
Authors: Montevilla López Gladis Andreina
Published: June 2023

El objetivo de la investigación fue proponer lineamientos de gobierno corporativo para organizaciones no gubernamentales en Bolivia. Se efectuó el análisis normativo en tres etapas: Gobierno corporativo en la legislación internacional y nacional; Marco legal comparado que regula a las organizaciones sin fines de lucro; Propuesta de lineamientos de gobierno corporativo. En el marco internacional se evidenciaron avances considerables relativos a la normativa que favorecen el desarrollo de estructuras de gobierno corporativo; en contraposición, en Bolivia se evidenciaron vacíos. En consecuencia, con base en guías y códigos internacionales enfocados a las organizaciones de la sociedad civil propiamente dicha, se propuso un conjunto de principios y prácticas recomendadas para que cada organización pueda definir una estructura de gobierno adecuada a su realidad, que le permita cumplir con su misión y objetivos de manera efectiva, eficiente, transparente y con probidad.
Cloning and Analysis of T-DNA Targeted Gene of Colletotrichum gloeosporioides Pathogenicity-Defective Strain Cs16
Authors: Hyder Moazam , Khaskheli Muhammad Ibrahim , Lodhi Abdul Mubeen , Bukero Aslam , Khan Raja Asad Ali , Nizamani Imtiaz Ahmed , Mahmood Raja Tahir , Mushtaq Aamar , Ji Zhirui
Published: June 2023

In preliminary stage, the nucleotide sequence of Cs16 Colletotrichum gloeosporioides associated gene obtained from database of (NCBI), analyzed with Clustalx 1.83 in order to assess the deduced amino acid sequences. The full-length sequences of Cs16 gene is including with specific Open Reading Frame (ORF) having 3’ and 5’ UTR was obtained. In order to assess the relationship of C. gloeosporioides associated CS16 gene with other members, a combined rooted neighbor-joining (NJ) tree was generated through MEGA 4.5 by following 1000 bootstrap replicates. The resulted alignment predicts that Cs16 gene showed entirely diverse sequences from other species and has no any conserved domain sequences between them. In order to scrutinize the full length nucleotide sequences, the gene functional cloning of Cs16 gene has been carried out by PCR amplification. To examine the functional analysis of Cs16 gene in C. gloeosporioides and its regulatory mechanisms, the over expressing vector (pGapneoR26) was transformed into Agrobacterium strain LBA4404 that resulted successful detection of GFP-Cs16 expression into C. gloeosporioides transformants and it was also substantially detected by fluorescence microscopy. The T-DNA intentional mutants of C. gloeosporioides mycelia illustrated phonotypic different intensification, colour, colony growth rate than wild type isolated C. gloeosporioides STIJ6 strain.
Penerapan Model Project Based Learning untuk Meningkatkan Hasil Belajar Seni Rupa Siswa Kelas IX-8 MTsN 3 Padang
Authors: Rahmadani Sherina Pasma , Wikarya Yusron
Published: June 2023

Penelitian ini bertujuan untuk meningkatkan Hasil Belajar Seni Rupa siswa Kelas IX-8 Mtsn 3 Padang melalui penerapan model pembelajaran Project Based Learning (PjBL). Populasi dalam penelitian ini adalah seluruh siswa kelas IX-8 MTsN 3 Padang yang berjumlah 27 orang. Metode yang digunakan dalam penelitian ini adalah Penelitian Tindakan Kelas (PTK). Metode dan alat pengumpulan data berupa observasi, tes, dan dokumentasi. Teknik analisis data di uji dengan menggunakan program SPSS versi 26. Hasil penelitian menunjukkan bahwa ada pengaruh yang signifikan dari penerapan pembelajaran Project Based Learning terhadap hasil belajar seni rupa siswa kelas IX-8 MTsN 3 Padang. Hal ini bisa dilihat dari tingkat ketuntasan hasil belajar siswa. Pada tahapan pra siklus yang tuntas sebanyak 10 siswa (37,03%), pada saat dilakukannya tahap siklus I mengalami peningkatan ketuntasan sebanyak 17 siswa (63%). Pada tahapan siklus II tingkat ketuntasan peserta didik meningkat secara signifikan sebanyak 25 siswa (92,59%). Dengan demikian dapat disimpulkan bahwa penerapan model Project Based Learning dapat meningkatkan hasil belajar seni rupa siswa kelas IX-8 MTsN 3 Padang.
Toàn văn tập 2 (số 2)
Authors: Y dược PNT
Published: June 2023

Toàn văn tập 2 (số 2)
THE EFFECT OF SOCIAL SECURITY ON EMPLOYEE PERFORMANCE WITH JOB SATISFACTION AS INTERVENING VARIABLES (Study from Administrative Section of Texas Public Health Facilities)
Authors: Jorge O Brusa  , Mohsen Bahmani-Oskooe
Published: June 2023

This study aims to determine“The Effect of Social Security on Employee Performance with Job Satisfaction as an Intervening Variable (Case Study in the Administrative Section of PT. Auto Padu Kuala Tanjung Batubara)”. The results of this study indicate that 1) it can be seen that tcount (7.314) > ttable (1.685), likewise with a significance value of 0.00 <0.05 it can be concluded that the first hypothesis is accepted, meaning that the social security variable(X) positive and significant effecton job satisfaction (Y1). 2) it can be seen that tcount (2.593) > ttable (1.685), and a significance value of 0.01 <0.05, it can be concluded that the second hypothesis is accepted, meaning social security(X) positive and significant effecton employee performance (Y2). 3) it can be seen that tcount (5.131) > ttable (1.685), and the significance value is 0.00 <0.05, it can be concluded that the third hypothesis is accepted, meaning job satisfaction (Y1)positive and significant effecton employee performance (Y2). 4) the direct effect of variable X on variable Y2 is 0.313. While the indirect effect through the Y1 variable is 0.765 x 0.619 = 0.473, the calculation results obtained show that the indirect effect through the Y1 variable is greater than the direct effect on the Y2 variable.
Uso de refugios por murciélagos en la Reserva Ecológica Arenillas, El Oro, Ecuador
Authors: Molina-Moreira Natalia , Alava Leonardo
Published: June 2023

Con el propósito de localizar refugios de murciélagos, identificar las especies que los habitan, su nicho trófico, describir el tipo de refugio y su entorno, desde el manglar hasta el bosque seco de la Reserva Ecológica Arenillas, en la provincia de El Oro, al suroeste del Ecuador, se realizaron cinco salidas de campo en cinco meses, de tres días cada una, con un esfuerzo de 120 horas/red. La búsqueda de refugios se hizo durante el día, mientras que durante la noche se establecieron seis puntos de muestreo con redes de neblina cerca de los refugios encontrados. Los murciélagos capturados en redes fueron identificados por medidas morfométricas, sexados y liberados en el sitio de muestreo. Se capturaron 122 individuos en los puntos de muestreo y en los refugios, más un individuo encontrado en la oficina de los guardaparques. Se identificaron ocho especies que pertenecen a cuatro gremios tróficos: nectarívoro, carnívoro, frugívoro e insectívoro. Las especies registradas en refugios naturales fueron tres: Glossophaga soricina, Carollia brevicauda y Vampyrum spectrum (Phyllostomidae). En refugios artificiales se registraron cinco especies: Glossophaga soricina, Artibeus fraterculus, Carollia brevicauda (Phyllostomidae), Molossus molossus (Molossidae) y Myotis nigricans (Vespertilionidae). Rhogeessa velilla y Sturnira bakeri no se observaron en ningún refugio. Se encontraron refugios compartidos entre A. fraterculus y G. soricina y entre C. brevicauda y G. soricina.
Moth Luna (Actias luna)
Authors: Kavalerskaia Alisa , Kazachkova Evgenia , Nikolić-Lukovska Nataša , Marinović Nela
Published: June 2023

The Luna moth (Actias luna) is American Moon Moth also known as the Nearctic moth of the family Saturniidae, subfamily Saturniinae, a group recognized as the giant silk moth. The Luna moth is found east of the Great Plains in the United States from Florida to Maine, North America, and Saskatchewan east through central Quebec to Nova Scotia, Canada. Luna moths are rarely found as vagrants in Western Europe. In June 1987, Luna moth appeared on a United States First Class postage stamp. Within two dozen butterflies have been honored in postage stamps, this was the only moth. This remarkable critter is recognizable by its wings. But, the most interesting thing about Luna Moth is that this insect doesn’t have a digestive system or a mouth. It lives only for about a week after leaving the cocoon and never eats.
Benjamin Button Jellyfish
Authors: Shangichev Nikolai , Blanka Balyi , Marinović Nela , Nikolić-Lukovska Nataša
Published: June 2023

As called immortal jellyfish species, the Benjamin Button of the deep, which can age backward and silently fall into the world's oceans, swarm by swarm. This jellyfish can transform from an adult into a baby, but unlike Benjamin Button, the jellyfish can do it repeatedly. In the Mediterranean Sea, this immortal jellyfish (Turritopsis dohrnii) was discovered in 1883. Its unique ability was discovered in the 1990s. It regularly reverts into a sexually immature stage after reproduction and when injured or starved. The only way it can die is to be eaten, removed from the water, or infected.
Aplikasi Virtual Tour Kampus Sekolah Tinggi Teknologi (STITEK) Bontang Dengan Menggunakan Metode Multimedia Development Live Cycle (MDLC)
Authors: Nurlinda  , Nugroho Abadi , Turahyo
Published: June 2023

Sekolah Tinggi Teknologi (STITEK) Bontang yang beralamat Jl. Letjen S Parman dan terdiri dari 3 gedung terpisah yaitu kampus utama, kampus kreatif dan laboratorium teknik elektro. Penyampaian informasi STITEK Bontang memanfaatkan media sosial seperti instagram, facebook, youtube serta media cetak. Tentunya media informasi yang disajikan hanya berupa gambar diam atau video penjelasan mengenai kampus STITEK Bontang sehingga bagi masyarakat yang berada di luar kota bontang tidak dapat melihat sarana prasarana yang disediakan tidak dapat diakses karena terkendala jarak. Virtual tour sering digunakan untuk menggambarkan berbagai video dan media fotografi berbasis panorama menunjukkan pandangan tak terputus, karena panorama berupa rangkaian foto atau panning video rekaman. Dari semua hal diatas, Penulis merancang sebuah aplikasi menggunakan Metode MDLC. Hasil dari penelitian ini menunjukan bahwa kampus STITEK Bontang dapat diakses gambar dan prasarananya secara fisik dalam bentuk virtual dengan sudut gambar 360 derajat
ANALISIS SENTIMEN FILM DI TWITTER MENGGUNAKAN METODE SUPPORT VECTOR MACHINE
Authors: Khairudin Mahdy , Sukendar Ade , Somantri Asep
Published: June 2023

Twitter adalah salah satu media sosial yang sering digunakan untuk berbagi informasi atau biasa disebut tweet secara realtime. Berdasarkan hasil penelitian pada tahun 2013 oleh Semiocast, lembaga riset media sosial, mengatakan bahwa jumlah pengguna Twitter di Indonesia terbanyak ketiga setelah Amerika Serikat dan Jepang dengan angka 6,5 persen pengguna dan 1 miliar tweet. Tweet biasanya dapat mempengaruhi minat beli, memilih suatu tokoh politik, atau menonton film mereka. Tweet berkaitan dengan film menjadi referensi bagi pengguna Twitter yang lain apabila ingin menonton film yang sama. Karena tidak adanya layanan yang yang menyediakan referensi film berdasarkan komentar orang lain yang relevan untuk penonton Indonesia. Penelitian ini untuk melakukan analisis sentimen terhadap tweet di Twitter pada kasus film berbahasa Indonesia yang menghasilkan rating film. Metode yang digunakan untuk analisis sentimen adalah dengan Support Vector Machine (SVM). Hasil akhir dari penelitian ini adalah sebuah model atau algoritma SVM yang dapat mengklasifikasikan atau analisis sentimen film berdasarkan tweet di Twitter dengan memanfaatkan Twitter API.
Sistem Pakar Diagnosis Penyakit Kulit Wajah Menggunakan Metode Dempster Shafer
Authors: Nur'asima  , Yuwanda Purnamasari Pasrun  , Andi Tenri Sumpala  , Mardiawati
Published: June 2023

Kulit wajah merupakan bagian paling sensitif, wajah mengalami berbagai perubahan yang disebabkan pengaruh lingkungan luar seperti pengaruh sinar matahari, iklim, polusi, penggunaan AC, trauma pada kulit, dan penggunaan produk perawatan atau tata rias yang tidak sesuai, maupun perubahan dari dalam tubuh misalnya pengaruh perubahan hormonal pada saat pubertas, menstruasi, kehamilan, pil KB, pengaruh zat gizi (nutrisi), dan lain-lain. Sebagian orang masih ada yang kurang memiliki pengetahuan tentang jenis penyakit kulit wajah yang diderita sehingga menggunakan produk kecantikan yang tidak sesuai dengan kulit wajahnya dan tanpa berkonsultasi terlebih dahulu kepada pakar. Sehingga mengakibatkan penyakit pada wajah bertambah parah. Oleh sebab itu dibutuhkan suatu aplikasi sistem pakar untuk membantu masyarakat dalam memecahkan masalah yang dihadapi, sistem pakar ini menggunakan metode Dempster shafer. Aplikasi Sistem Pakar ini dapat mendiagnosis penyakit kulit wajah menggunakan metode Dempster Shafer. Berdasarkan hasil pengujian akurasi yang telah dilakukan pada sistem pakar menghasilkan tingkat keakuratan sebesar 80%.
Fracture toughness tests at 77 K and 4 K on 316L stainless steel welded plates
Authors: Benzing Jake , Derimow Nick , Lucon Enrico , Weeks Timothy
Published: June 2023

In the framework of a collaborative project between ASME, NASA, and NIST, quasi-static fracture toughness tests have been performed at liquid nitrogen temperature (77 K, or -196 °C) and liquid helium temperature (4 K, or -269 °C) on weld specimens extracted from the centers of four 316L welded stainless steel plates, each produced by a different vendor. Although the plates were produced in accordance with the same specifications from the same material (316L), large differences in fracture toughness have been observed, with the best weld (W2) exhibiting almost twice the critical toughness of the worst (W1) at 77 K (219 kJ/m2 vs. 113 kJ/m2), and about seven times the critical toughness of W1 at 4 K (146 kJ/m2 as compared to 21 kJ/m2). The Charpy absorbed energies recorded at 77 K for three of the welds within the same project were found to be strongly linearly correlated with fracture toughness at both test temperatures. The exception was weld W4, which provided the highest impact toughness and the second lowest quasi-static fracture toughness (stable crack initiation and resistance to crack propagation).
Complexity and rigidity of Ulrich modules, and some applications
Authors: Dey Souvik , Ghosh Dipankar
Published: June 2023

We analyze whether Ulrich modules, not necessarily maximal CM (Cohen-Macaulay), can be used as test modules, which detect finite homological dimensions of modules. We prove that Ulrich modules over CM local rings have maximal complexity and curvature. Various new characterizations of local rings are provided in terms of Ulrich modules. We show that every Ulrich module of dimension $s$ over a local ring is $(s+1)$-Tor-rigid-test, but not $s$−Tor-rigid in general (where $s\ge 1$). Over a deformation of a CM local ring of minimal multiplicity, we also study Tor rigidity.
САВРЕМЕНО ДРУШТВО И МУЛТИКУЛТУРАЛНА БИБЛИОТЕКА
Authors: Симић Наташа Ј.
Published: June 2023

Савремено друштво принуђено је да се прилагоди променама које намеће развој како појединца, тако и привреде у оквиру самог друштва или окружења. Промене у друштву поставиле су захтеве за креирање различитих модела како у култури тако и у образовању. Последњих деценија друштвена стварност се брзо мењала, што значи да су наука и технологија имале утицај на све сфере рада и живота. Друштво и библиотека су међусобно повезани, уколико друштво жели да побољша свој начин живота, прво мора да унапреди библиотеку. Библиотека ствара нове начине за ширење информација, па тако постаје информациони, културни и образовни центар. Државе које имају добре библиотеке у свом друштву имају успешне грађане у свим сферама живота. За библиотеке је веома важно да се прилагођавају променама у друштву, како би могле да задрже свој статус као установе културе. Библиотеке су се на почетку овог века суочиле се врло сложеним изазовима друштвених промена. Афирмација негативних и урушавање позитивних друштвених вредности умногоме су промениле улогу и значај библиотеке. Ипак, и поред свих изазова библиотека успева да сачува сврху свог постојања а то је да у сваком тренутку буде у служби знања, да у њој свако има своје место без обзира на статус, занимање, пол, националну и расну припадност. Како се наводи у ИФЛА Смерницама за мултикултуралне библиотеке, библиотека је корак ка дијалогу различитих култура једног друштва. За тридесет година каталогизације у Народној библиотеци Србије као националног каталошког центра, обрађено је хиљаде публикација на свим језицима народа и народности. Услуга мултикултуралне библиотеке треба да осликава различитост културе и језика мултикултурне средине, при чему ће допринети заштити културне самосвести.
ЗБИРКА КЊИГА ШТАМПАНА ГОТИЦОМ
Authors: Петронић Маријана
Published: June 2023

У мају мјесецу 2013. године Матична библиотека Источно Сарајево је од Јеврејске општине Сарајево добила на поклон вриједне књиге, заоставштину породице Михаћ, тачније, кћерке Петра и Мирјане Михаћ, проф. др Татјане Михаћ. О професорици Татјани Михаћ остало је мало писаних података али врло драгоцјених. Сву своју заоставштину поклонила је Јеврејској општини Сарајево, а они су књиге, већином штампане готицом, прослиједили Матичној библиотеци Источно Сарајево. Ради се о укупном броју од 350 књига, од чега је готицом штампано око 200. Ове књиге представљале су прави изазов за каталогизацију с обзиром на то да је готица као писмо престала да се користи до 1942. године, по свој прилици због непрактичности, али и због надолазећег нацизма. Примијетно је да су Михаћеви књиге брижљиво чували, те да се ради о бираним насловима вриједне класичне књижевности (Хајне, Твен, Ками, Ман, Толстој, Гете, браћа Грим, Лесинг, Бокачо...). На књигама се могу наћи и потписи некадашњих власника. Уз збирку је стигла и свеска са уредно пописаним књигама, те школски рјечници гдје се може видјети да је породица Михаћ била врло образована и да су говорили по четири- пет страних језика. Примјера ради, професорица Татјана Михаћ је говорила њемачки, енглески и руски језик. Иначе, била је редовни професор Одсјека за физику на Природно-математичком факултету Сарајево до 1. марта 2012. године када је отишла у пензију.
Murine Alveolar Macrophages Rapidly Accumulate Intranasally Administered SARS-CoV-2 Spike Protein leading to Neutrophil Recruitment and Damage
Authors: Park Chung , Hwang Il-Young , Yan Serena Li-Sue , Vimonpatranon Sinmanus , Wei Danlan , Van Ryk Don , Cicala Claudia , Arthos James , Kehrl John H.
Published: June 2023

The trimeric SARS-CoV-2 Spike protein mediates viral attachment facilitating cell entry. Most COVID-19 vaccines direct mammalian cells to express the Spike protein or deliver it directly via inoculation to engender a protective immune response. The trafficking and cellular tropism of the Spike protein in vivo and its impact on immune cells remains incompletely elucidated. In this study we inoculated mice intranasally, intravenously, and subcutaneously with fluorescently labeled recombinant SARS-CoV-2 Spike protein. Using flow cytometry and imaging techniques we analyzed its localization, immune cell tropism, and acute functional impact. Intranasal administration led to rapid lung alveolar macrophage uptake, pulmonary vascular leakage, and neutrophil recruitment and damage. When injected near the inguinal lymph node medullary, but not subcapsular macrophages, captured the protein, while scrotal injection recruited and fragmented neutrophils. Wide-spread endothelial and liver Kupffer cell uptake followed intravenous administration. Human peripheral blood cells B cells, neutrophils, monocytes, and myeloid dendritic cells all efficiently bound Spike protein. Exposure to the Spike protein enhanced neutrophil NETosis and augmented human macrophage TNF-α and IL-6 production. Human and murine immune cells employed C-type lectin receptors and Siglecs to help capture the Spike protein. This study highlights the potential toxicity of the SARS-CoV-2 Spike protein for mammalian cells and illustrates the central role for alveolar macrophage in pathogenic protein uptake.
Microbially-derived indole-3-acetate alleviates diet induced steatosis and inflammation in mice
Authors: Ding Yufang , Yanagi Karin , Yang Fang , Callaway Evelyn , Cheng Clint , Hensel Martha E , Menon Rani , Alaniz Robert C. , Lee Kyongbum , Jayaraman Arul
Published: June 2023

Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in Western countries. There is growing evidence that dysbiosis of the intestinal microbiota and disruption of microbiota-host interactions contribute to the pathology of NAFLD. We previously demonstrated that gut microbiota derived tryptophan metabolite indole-3-acetate (I3A) was decreased in both cecum and liver of high-fat diet-fed mice and attenuated the expression of inflammatory cytokines in macrophages and TNF-a and fatty acid induced inflammatory responses in an aryl-hydrocarbon receptor (AhR) dependent manner in hepatocytes. In this study, we investigated the effect of orally administered I3A in a mouse model of diet induced NAFLD. Western diet (WD)-fed mice given sugar water (SW) with I3A showed dramatically decreased serum ALT, hepatic TG, liver steatosis, hepatocyte ballooning, lobular inflammation, and hepatic production of inflammatory cytokines, compared to WD-fed mice given only SW. Metagenomic analysis show that I3A administration did not significantly modify the intestinal microbiome, suggesting that I3A’s beneficial effects likely reflect the metabolite’s direct actions on the liver. Administration of I3A partially reversed WD induced alterations of liver metabolome and proteome, notably, decreasing expression of several enzymes in hepatic lipogenesis and β-oxidation. Mechanistically, we also show that AMP-activated protein kinase (AMPK) mediates the anti-inflammatory effects of I3A in macrophages. The potency of I3A in alleviating liver steatosis and inflammation clearly demonstrates its potential as a therapeutic modality for preventing the progression of steatosis to NASH.
The molecular clock in long-lived tropical trees is independent of growth rate
Authors: Satake Akiko , Imai Ryosuke , Fujino Takeshi , Tomimoto Sou , Ohta Kayoko , Na’iem Mohammad , Indrioko Sapto , Widiyatno  , Purnomo Susilo , Mollá–Morales Almudena , Nizhynska Viktoria , Tani Naoki , Suyama Yoshihisa , Sasaki Eriko , Kasahara Masahiro
Published: June 2023

The rates of appearance of new mutations play a central role in evolution. However, mutational processes in natural environments and their relationship with growth rates are largely unknown, particular in tropical ecosystems with high biodiversity. Here, we examined the somatic mutation landscapes of two tropical trees,
Shorea laevis
(slow- growing) and
S. leprosula
(fast-growing), in central Borneo, Indonesia. Using newly- constructed genomes, we identified a greater number of somatic mutations in tropical trees than in temperate trees. In both species, we observed a linear increase in the number of somatic mutations with physical distance between branches. However, we found that the rate of somatic mutation accumulation per meter of growth was 3.7-fold higher in
S. laevis
than in
S. leprosula
. This difference in the somatic mutation rate was scaled with the slower growth rate of
S. laevis
compared to
S. leprosula,
resulting in a constant somatic mutation rate per year between the two species. We also found that somatic mutations are neutral within an individual, but those mutations transmitted to the next generation are subject to purifying selection. These findings suggest that somatic mutations accumulate with absolute time and older trees have a greater contribution towards generating genetic variation.The significance of our study lies in the discovery of an absolute time-dependent accumulation of somatic mutations in long-lived tropical trees, independent of growth rate. Through a comparative analysis of somatic mutation landscapes in slow- and fast-growing species, we observed a clock-like accumulation of somatic mutations in both species, regardless of their growth rates. Although the majority of somatic mutations were restricted to a single branch, we also identified mutations present in multiple branches, likely transmitted during growth. Our findings suggest that older trees make a greater contribution towards generating genetic variation.
High-throughput Automated Muropeptide Analysis (HAMA) Reveals Peptidoglycan Composition of Gut Microbial Cell Walls
Authors: Hsu Ya-Chen , Su Pin-Rui , Huang Lin-Jie , Cheng Kum-Yi , Chen Chun-hsien , Hsu Cheng-Chih
Published: June 2023

Peptidoglycan (PGN), a net-like polymer constituted by muropeptides, provides protection for microorganisms and has been one of the major targets for antibiotics for decades. Researchers have explored host-microbiome interactions through PGN recognition systems and discovered key muropeptides modulating host responses. However, most common characterization techniques for muropeptides are labor-intensive and require manual analysis of mass spectra due to the complex cross-linked PGN structures. Each species has unique moiety modifications and inter-/intra-bridges, which further complicates the structural analysis of PGN. Here, we developed a high-throughput automated muropeptide analysis (HAMA) platform leveraging tandem mass spectrometry and
in silico
muropeptide MS/MS fragmentation matching to comprehensively identify muropeptide structures, quantify their abundance, and infer PGN cross-linking types. We demonstrated the effectiveness of the HAMA platform using well-characterized PGNs from
E. coli
and
S. aureus
and further applied it to common gut bacteria including species of
Bifidobacterium, Bacteroides, Lactobacillus, Enterococcus,
and
Akkermansia.
We thoroughly explored their PGN structures accurately identified muropeptide mono-/multi-mers, and even unambiguously discriminated the structural isomers via the HAMA platform. Furthermore, we found that the cell stiffness may be correlated to the compactness of the PGN structures through the length of interpeptide bridges or the site of transpeptidation within
Bifidobacterium
species. In summary, the HAMA framework exhibits an automated, intuitive, and accurate analysis of PGN compositions, which may serve as a potential tool to investigate the post-synthetic modifications of saccharides, the variation in interpeptide bridges, and the types of cross-linking within bacterial PGNs.
High-throughput Automated Muropeptide Analysis (HAMA) Reveals Peptidoglycan Composition of Gut Microbial Cell Walls
Authors: Hsu Ya-Chen , Su Pin-Rui , Huang Lin-Jie , Cheng Kum-Yi , Chen Chun-hsien , Hsu Cheng-Chih
Published: June 2023

Peptidoglycan (PGN), a net-like polymer constituted by muropeptides, provides protection for microorganisms and has been a major target for antibiotics for decades. Researchers have explored host-microbiome interactions through PGN recognition systems and discovered key muropeptides modulating host responses. However, most common characterization techniques for muropeptides are labor-intensive and require manual analysis of mass spectra due to the complex cross-linked PGN structures. Each species has unique moiety modifications and inter-/intra-bridges, which further complicates the structural analysis of PGN. Here, we developed a high-throughput automated muropeptide analysis (HAMA) platform leveraging tandem mass spectrometry and
in silico
muropeptide MS/MS fragmentation matching to comprehensively identify muropeptide structures, quantify their abundance, and infer PGN cross-linking types. We demonstrated the effectiveness of HAMA platform using well-characterized PGNs from
E. coli
and
S. aureus
and further applied it to common gut bacteria including
Bifidobacterium, Bacteroides, Lactobacillus, Enterococcus,
and
Akkermansia muciiniphila.
Specifically, we found that the stiffness and strength of the cell envelopes may correspond to the lengths and compositions of interpeptide bridges within
Bifidobacterium
species. In summary, the HAMA framework exhibits an automated, intuitive, and accurate analysis of PGN compositions, which may serve as a potential tool to investigate the post-synthetic modifications of saccharides, the variation in interpeptide bridges, and the types of cross-linking within bacterial PGNs.
A systematic review on artificial intelligence techniques for detecting thyroid diseases
Authors: Aversano Lerina , Bernardi Mario Luca , Cimitile Marta , Maiellaro Andrea , Pecori Riccardo
Published: June 2023

The use of artificial intelligence approaches in health-care systems has grown rapidly over the last few years. In this context, early detection of diseases is the most common area of application. In this scenario, thyroid diseases are an example of illnesses that can be effectively faced if discovered quite early. Detecting thyroid diseases is crucial in order to treat patients effectively and promptly, by saving lives and reducing healthcare costs. This work aims at systematically reviewing and analyzing the literature on various artificial intelligence-related techniques applied to the detection and identification of various diseases related to the thyroid gland. The contributions we reviewed are classified according to different viewpoints and taxonomies in order to highlight pros and cons of the most recent research in the field. After a careful selection process, we selected and reviewed 72 papers, analyzing them according to three main research questions, i.e., which diseases of the thyroid gland are detected by different artificial intelligence techniques, which datasets are used to perform the aforementioned detection, and what types of data are used to perform the detection. The review demonstrates that the majority of the considered papers deal with supervised methods to detect hypo- and hyperthyroidism. The average accuracy of detection is high (96.84%), but the usage of private and outdated datasets with a majority of clinical data is very common. Finally, we discuss the outcomes of the systematic review, pointing out advantages, disadvantages, and future developments in the application of artificial intelligence for thyroid diseases detection.
Naturaleza y belleza escénica. Estudio de los juicios de preferencia en paisajes naturales
Authors: Corraliza José Antonio , de Frutos Belinda , Moll Adrián
Published: June 2023

Fernando González Bernáldez contribuyó decisivamente a abrir el amplio campo de los estudios de estética ambiental, introduciendo modelos de relevancia en la investigación psicológica de la percepción del paisaje. En este trabajo se recopilan los principales modelos teóricos de referencia que aún son relevantes en el desarrollo de esta línea de investigación. Se evalúa una colección experimental de 16 paisajes de entornos naturales en una muestra de 302 participantes. Los resultados muestran la relevancia de la presencia de agua y vegetación en la preferencia por un paisaje. Se propone un modelo integrado que describe de la estética de los paisajes naturales. Este modelo incluye las variables de claridad, contenido explícito de la escena, variables sociales y de la experiencia de fascinación.
Exploring Elements of Workplace Social Capital that Impact the Accommodation Negotiation Process: A Qualitative Descriptive Study
Authors: Hossain Sabrina , Moll Sandra , Tompa Emile , Gewurtz Rebecca
Published: June 2023

The concept of social capital may shed light on challenges experienced by employees with mental health conditions (MHC) in sustaining employment. This article presents findings from a qualitative descriptive study exploring the concept of workplace social capital and its impact on how employees with MHC negotiate workplace accommodations. The findings reveal that social capital consists of various elements that impact how accommodations are negotiated in the workplace; some are dynamic and can be built, rebuilt, and spent such as employee self-confidence, reputation, and likeability. Future research is needed to explore how social capital can be developed to facilitate the accommodation process.
Spatial and Temporal Variations of Land Use and Land Cover In Kadiri Watershed Using Rs & Gis Techniques
Authors: Rao B. V. Mohana , Mani A. , Devi B. Sarojini , Vishnuvardhan S. , Rao Ch. Sujani
Published: June 2023

The change detection and land use and land cover (LULC) maps are more important powerful forces behind numerous ecological systems and fallow land. It is widely known that land use/land cover (LULC) changes significantly alter watershed hydrology and sediment yields. The impact, especially on erosion and sedimentation, is likely to be exacerbated in regions dominated by high rainfall patterns such as monsoons. RS & GIS technologies are very useful to determine the LULC changes. Present research area Kadiri Watershed of Anantapur district of Andhra Pradesh, India, drains an area about 240 km2 including 15 villages. The average annual rainfall in this area varies between 600mm to 700mm in which 60%, 35% and 5% of total rainfall occurs in South-West (S-W),North-East (N-E) and in Summer seasons respectively. The current research focuses on demarcating the spatiotemporal LULC changes. These effects directly affect the ecosystem, land resources, cropping pattern and agriculture. LULC assessment and surveillance are essential for long-term planning and sustainable use of natural resources. The LULC maps were prepared for the study area using Landsat-5, Senthinel 2 images pertaining to pre-monsoon and post-monsoon seasons of 2013, 2017 and 2021. Variations in the extents of agriculture, plantations, scrubs, water bodies, open lands, and built-up areas were noted during these years in the pre-monsoon season, and they ranged from 22 to 35 and 43%, 2 to 3 and 5%, 22 to 28%, 1 to 4%, 52 to 29 and 15%, as well as 1 to 5%, respectively. Similar fluctuations were seen in the post-monsoon season, where they ranged from 29 to 40 and 47%, 3 to 7%, 33 to 30%, 2 to 4%, 32 to 20 and 7%, as well as 1 to 5%. Kadiri watershed, an agriculturally dominant area, has seen an increase in cultivated land due to the conversion of fallow land and open scrub into cropland as a result of good rainfall received during the south-west monsoon during in assessment years and implementation of watershed development activities. These findings highlight the potential impacts of LULC changes in a monsoon-dominated watershed and may contribute to the development of successful LULC-based watershed management strategies for prevention of flooding and sediment loss.
Effect of Entrepreneurial Characteristics on Decision Making Process
Authors: Agilan A. , Sivakumar S. D. , Hemalatha S. , Balasubramaniam P. , Anandhi V.
Published: June 2023

The main objective of the paper is to examine the effect of entrepreneurial characteristics on decision making process. The research was conducted with 120 entrepreneurs from sago cluster listed in Sago serve in Tamil Nadu. Samples were drawn randomly from the population. In this study the effect of entrepreneur’s characteristics were examined with formalized decision making process using multiple regression. The entrepreneur’s characteristics taken for the study were Risk propensity, Locus of control, Optimism, Competitiveness and Innovativeness. Results showed that entrepreneurs optimistic behavior predicted highest to the formalized decision making process.
Valorization of tropical fruit peel powders: Physicochemical composition, techno-functional properties, and in vitro antioxidant and antidiabetic activities
Authors: Marquez Molina Ofelia , Domínguez-Avila Jesús Abraham , Lopez-Martínez Leticia Xochitl , Pareek Sunil , Madera Santana Tomas Jesús , González Aguilar Gustavo Adolfo
Published: June 2023

This study aims to evaluate the physico-chemical composition, techno-functional properties and in vitro antioxidant and antidiabetic activities of papaya, pineapple and mango peels for their possible use as functional ingredients. The peel powders were found to possess interesting techno-functional properties, high dietary fiber content (37.77 to 62.26%) and phenolic compounds, namely gallic, ferulic, and p-coumaric acid, catechin, quercetin-3-β-d-glucoside and quercetin. They also showed excellent antioxidant activity, as determined by ABTS (3.63 to 29.8 µM TE/g), DPPH (5.76 to 35.3 µM TE/g), NO (60.67 to 86.35%) and O (17.56 to 50.64%). Mango peel powders presented the best ability to inhibit the activity of the different enzymes evaluated: modest α-amylase inhibition (51.40%), stronger α-glucosidase inhibitory activities (70.32%), and moderate antiglycation potential (57.15%). Peel powders of these tropical fruits make them suitable to be used as food ingredients with possible health benefits, improving intestinal function and controlling hyperglycemia. Further studies require animal models and, subsequently, in humans.
Keywords: Bioactivities; Nutritional value; Peels; Techno-functional properties; Tropical fruits
Cystic Fibrosis
Authors: Ong Thida , Ramsey Bonnie W.
Published: June 2023

Importance

Cystic fibrosis, a genetic disorder defined by variants in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, affects more than 30 000 individuals in the US and approximately 89 000 worldwide. Absent or decreased function of the CFTR protein is associated with multiorgan dysfunction and shortened life expectancy.

Observations

CFTR is an anion channel in the apical membrane of epithelial cells. Loss of function leads to obstructed exocrine glands. Of people with cystic fibrosis in the US, approximately 85.5% have the gene variant F508del. Manifestations of cystic fibrosis in patients with the F508del gene variant begin in infancy with steatorrhea, poor weight gain, and respiratory symptoms (coughing, wheezing). As people with cystic fibrosis age, chronic respiratory bacterial infections cause loss of lung function and bronchiectasis. With the availability of universal newborn screening in multiple countries including the US, many people with cystic fibrosis are asymptomatic at diagnosis. With multidisciplinary care teams that included dietitians, respiratory therapists, and social workers, treatment of cystic fibrosis can slow disease progression. Median survival has improved from 36.3 years (95% CI, 35.1-37.9) in 2006 to 53.1 years (95% CI, 51.6-54.7) in 2021. Pulmonary therapies for patients with cystic fibrosis consist of mucolytics (eg, dornase alfa), anti-inflammatories (eg, azithromycin), and antibiotics (such as tobramycin delivered by a nebulizer). Four small molecular therapies, termed CFTR modulators, that facilitate CFTR production and/or function have received regulatory approval. Examples are ivacaftor and elexacaftor-tezacaftor-ivacaftor. For example, in patients with 1 F508del variant, the combination of ivacaftor, tezacaftor, and elexacaftor improved lung function from −0.2% in the placebo group to 13.6% (difference, 13.8%; 95% CI, 12.1%-15.4%) and decreased the annualized estimated rate of pulmonary exacerbations from 0.98 to 0.37 (rate ratio, 0.37; 95% CI, 0.25-0.55). Improved respiratory function and symptoms have lasted up to 144 weeks in postapproval observational studies. An additional 177 variants are eligible for treatment with the elexacaftor-tezacaftor-ivacaftor combination.

Conclusion

Cystic fibrosis affects approximately 89 000 people worldwide and is associated with a spectrum of disease related to exocrine dysfunction, including chronic respiratory bacterial infections and reduced life expectancy. First-line pulmonary therapies consist of mucolytics, anti-inflammatories, and antibiotics, and approximately 90% of people with cystic fibrosis who are 2 years or older may benefit from a combination of ivacaftor, tezacaftor, and elexacaftor.
Output voltage regulation of a fuel cell/boost converter system with uncertain load: An adaptive PI‐PBC approach
Authors: Cisneros Rafael , Ortega Romeo , Beltrán Carlo A. , Langarica‐Cordoba Diego , Díaz‐Saldierna Luis. H.
Published: June 2023

In this article, we consider the problem of voltage regulation of a proton exchange membrane fuel cell connected to an uncertain load through a boost converter. We show that, in spite of the inherent nonlinearities in the current‐voltage behavior of the fuel cell, the voltage of a fuel cell/boost converter system can be regulated with a simple proportional‐integral (PI) action designed following the passivity‐based control approach. The system under consideration consists of a DC–DC converter interfacing a fuel cell with a resistive load. We show that the output voltage of the converter converges to its desired constant value for all the systems initial conditions—with convergence ensured for all positive values of the PI gains. This latter feature facilitates the, usually difficult, task of tuning the gains of the PI. An immersion and invariance parameter estimator is afterward proposed which allows the operation of the PI passivity‐based control when the load is unknown, maintaining the output voltage at the desired level. The stable operation of the overall system is proved and the approach is validated with extensive numerical simulations considering real‐life scenarios, where robust behavior in spite of load variations and the presence of noise is obtained.