bluuebunny/crossref_metadata_2025 huggingface dataset:
Optical Nanoscopy Enabled by Nanophotonics
Authors: LEE Yeon Ui
Published: March 2023

Optical nanoscopy employs the principles of nanophotonics to improve the spatiotemporal resolution by manipulating light at the nanoscale. By integrating nanophotonic structures, such as nanoscale waveguides and metal/dielectric nanostructures, with fluorescence-based imaging methods, optical nanoscopy achieves sub-diffraction-limit resolution. This rapidly developing research field holds exciting potential for advancing our understanding of the nanoscopic world and revealing insights beyond conventional optical microscopy.
Las redes de In Ezechielem Explanationes. Correspondencia romana de Villalpando y otros documentos
Authors: Rueda Galán Luis
Published: March 2023

El Archivo Histórico de la Pontificia Universidad Gregoriana conserva entre sus importantes fondos un conjunto documental relacionado con la labor del arquitecto-matemático Juan Bautista Villalpando SJ durante su larga estancia en el Colegio Romano de la Compañía de Jesús (1590-1608), y sobre la preparación del comentario a Ezequiel y la restitución del Templo de Jerusalén contenidas en su obra In Ezechielem explanationes. Este artículo estudia correspondencia enviada por eruditos europeos a Villalpando, junto a un manuscrito ilustrado obra del jesuita, en relación fundamentalmente con la gestación de los aspectos arquitectónicos y gráficos de su proyecto editorial.
Encuentros y desencuentros con la arquitectura de vanguardia: la crítica arquitectónica de Torres Balbás (1918-1933)
Authors: Barrios Rozúa Juan Manuel
Published: March 2023

Torres Balbás fue un prolífico escritor que contó desde el principio con una revista en la que pudo publicar con regularidad sus críticas. Por ello lo que en cualquier arquitecto habrían sido debates interiores de los que solo conoceríamos sus conclusiones, en él son reflexiones a puerta abierta en las que observamos contradicciones y certezas, caminos que abandona y senderos que descubre. El arquitecto madrileño animó a la renovación de la arquitectura haciéndose eco de propuestas internacionales muy diversas, incluidas las de Le Corbusier, aunque vio la senda más factible para la atrasada España en su maestro Antonio Flórez. Ya abandonada su labor de crítico, chocó con el GATEPAC a cuenta de la arquitectura escolar.
Un “Nuevo Guernica” desconocido de Agustín Ibarrola: El cartel inédito para la Feria del Toro de Pamplona (1974)
Authors: Azanza López José Javier
Published: March 2023

Este trabajo recupera una obra desconocida en la producción de Agustín Ibarrola: su boceto inédito para el cartel de la Feria del Toro de Pamplona de los Sanfermines de 1974, que por estética, iconografía y significado se integra de pleno en los “nuevos Guernicas” que venía componiendo desde mediados de los años sesenta. El boceto plasma los dos elementos en torno a los cuales giraba en aquel momento su universo creador: el Guernica y la exaltación de la lucha obrera, con el icónico puño en alto, de gran fuerza en el imaginario visual vasco. La investigación revela el papel mediador de Jorge Oteiza en el encargo a Ibarrola, contextualiza el boceto en el momento reflexivo y creador del artista vizcaíno, y profundiza en las razones por las cuales no fue finalmente aceptado, debido a su marcado componente sociopolítico que lo alejaba de su finalidad festiva.
Virtual World as a Resource for Hybrid Education
Authors: Díaz Jairo Eduardo Márquez , Saldaña Camilo Andrés Domínguez , Ávila Camilo Alberto Rodríguez
Published: March 2023

The virtual worlds in the educational environment, have opened new possibilities to innovation in the teaching-learning process, where the flexibility of access to information inside or outside the classroom through an avatar, tends to a paradigm shift in education traditional, in terms of the way of transmitting and acquiring knowledge through technological means. In this sense, an investigation was carried out on the design, development and use of a metaverse as a digital tool of didactic support to students of the Faculty of Systems Engineering of the University of Cundinamarca, with a view to establishing its viability to be implemented in a course of mathematics and demonstrate the possibilities offered by this type of resource to motivate the student in his training. The metaverse design included various ICT tools, thereby promoting self-learning and collaborative learning. Finally, it was evaluated what was the appreciation of a group of students against their interaction with the metaverse, which validated its usefulness and functionality inside and outside the classroom.
Bilan chronologique de la culture nok et nouvelles datations sur des sculptures
Authors: Boullier Claire , Person Alain , Saliège Jean-François , Polet Jean
Published: March 2023

Depuis le début des années 90, la région de Jos (Nigéria central) subit un pillage sans précédent de ses sites archéologiques qui a mis au jour plusieurs milliers de sculptures principalement destinées au marché de l'art occidental. Dans la cavité de certaines de ces sculptures, étudiées dans le cadre d'une thèse de doctorat, du charbon de bois a été retrouvé et daté par la méthode du radiocarbone. La publication de ces nouvelles données est l'occasion de faire un bilan critique des informations chronologiques déjà connues et de réviser la fourchette chronologique de la culture nok. La découverte de ces charbons de bois complète aussi nos connaissances sur les techniques de fabrication et notamment sur l'usage d'armatures de soutien insérées à l'intérieur de certaines sculptures avant la cuisson.
Mégalithisme chez les Konso (Éthiopie)
Authors: Joussaume Roger , Bekele Metasebia
Published: March 2023

Dans le sud de l’Éthiopie, de part et d’autre de la Rift Valley, entre le Xe et le XIVe siècle de notre ère, des milliers de stèles ont été élevées à la mort de certains personnages. Aucune trace écrite ne concerne cette période qui appartient donc à la Protohistoire récente. Pour tenter d’éclairer le sujet, les auteurs ont entrepris d’étudier des peuples actuels (Konso et Gewada) habitant ces régions du sud et qui dressent des pierres sur les tombes de leurs héros.
Evaluation of Protective Properties of Lacquer Coatings on Copper Products Operating in a Low Aggressive Corrosive Environment
Authors: Davydov Artem D. , Kovalev Mark , Lyashenko Daniil
Published: March 2023

Lacquered copper membranes are sometimes used in operate equipment containing low aggressive corrosive water-based fluids. In some cases, the lacquer coating does not prevent the occurrence of corrosive processes leading to through damage to the product and equipment failure. In this work, a review of the most common copper corrosion mechanisms is carried out. During a visual inspection of the products, the peculiarities of the state of the membrane surfaces and corrosive damage were noted. On the basis of metallographic, X-ray structural and electrochemical studies, the assumptions put forward at the stage of visual inspection were confirmed. The conclusions contain assumptions about the reasons for the formation of pitting corrosion on copper membranes.
Utilization of Magnesium-Rich Synthetic Gypsum as Partial Replacement Material in Concrete
Authors: Noh Hamidun Mohd , Mohamad Nor Lailatul Izzatil Azwani , Idris Nur Ain , Kasim Narimah , Zainal Rozlin , Musa Sharifah Meryam Shareh
Published: March 2023

The high demand of concrete has increased the rate of the ecosystem as well as increase the carbon emissions of the cement industry. The rapid growth of construction puts a severe strain on our natural resources and endangers the environment. Therefore, there is a pressing need for a green alternative that will protect the environment and preserve resources. Hence, this study is carried out to reduce the usage of cement in concrete production. The new replacement technique utilized the magnesium-rich synthetic gypsum (MRSG) and silica fume (SF). The MRSG and SF will be used as partial replacement of cement in the range of 5% to 30% with a water to cement ratio of 0.55. These mixtures were formed into cube specimens of 100 x 100 x 100 mm size. Then, the compressive strength was conducted to determine the strength of the specimens. The results indicated that 10% cement replacement from 5% of MRSG residue and 5% of SF gives an optimum strength compared to the control specimen with 24.6 MPa and 25.8 MPa, respectively. In addition, the increased percentage of MRSG residue, increased the water absorption of the mix. The replacement of MRSG residue in concrete would not only provide economic relief but also help to create a sustainable and pollution-free environment as the disposing of this waste creates many inconveniences to the living organism.
Thermal Annealing Effects on the Raman and Photoluminescence Properties of Mono and Few-Layer MoS2 Films
Authors: Munkhbayar G. , Nomin-Erdene Erdenebat , Davaasambuu Jav
Published: March 2023

In this study, we report that the thermal treatment effects on the Raman and photoluminescence (PL) spectra of mono and few-layer MoS2 films by annealing in the vacuum and air at 300°C, respectively. The MoS2 film samples were prepared on silicon substrate by exfoliating from a bulk MoS2 crystal with a micromechanical exfoliation. For characterization of structural properties of the MoS2 films and identification of the Raman active modes, Raman spectrometer equipped with a He-Ne laser source and an optical microscope has been used. The results show that the vacuum annealing 7L MoS2 decreases the Full Width at Half Maximum (FWHM) of the Raman active modes as E12g, A1g and the vacuum annealing 1L MoS2 increases the PL intensity and peak energy, for 60% and 13.3meV, respectively also air annealing bilayer MoS2 increased the PL intensity (IA) and peak energy (EA), respectively for 85% and 15.4 meV (300°C for 40 min). After thermal annealing (vacuum and air), we observe that the indirect bandgap of the few-layer MoS2 was changed.
Economic cost of human fatalities due to road traffic accidents in Sri Lanka: an estimation based on the human capital approach
Authors: Gunaruwan T. L. , Nayanalochana P. C. J.
Published: March 2023

Though a key factor behind the economic growth of a nation, transportation is associated with negative externalities that directly affect the economic performance of a country: road traffic accidents being one such negative externality. An increase in the number of accidents and related fatalities poses a socio-economic burden to developed and developing countries alike. Hence, quantifying the impact of road traffic fatalities on the national economy has become a popular topic amongst researchers in transportation.
The present study was an attempt to quantify the economic burden of premature mortalities associated with road traffic accidents in Sri Lanka, using descriptive analytical tools and employing the Human Capital Approach, upon estimating the Years of Life Lost, an integral component of Disability-adjusted Life Years.
The outcomes revealed that road traffic accidents have been a growing threat in Sri Lanka, and that, despite the decreasing number of accidents, fatalities associated with road traffic accidents have increased: this reflects a trend of increasing accident severity. The results also allowed for an estimation of the human capital-related economic cost of fatalities due to road traffic accidents. This was found to be nearly 0.25% of the GDP of the corresponding years: exceeding the capital expenditure of the Government in the health sector and more than half that in the education sector.
Road segmentation: exploiting the efficiency of skip connections for efficient semantic segmentation
Authors: Madhumita D. , Bharath H. A. , Devendra V. P. , Shivam B.
Published: March 2023

Extraction of features is a unique approach that has several real-time applications. In remote sensing, road feature extraction includes recognising and extracting essential information about roads from high-resolution remote sensing photos. This data may include the shape, size, direction, and connection of roadways and their surroundings we can increase the accuracy and efficiency of road recognition algorithms and better comprehend the geographical distribution of roads in metropolitan settings. Nevertheless, traditional techniques of road recognition sometimes rely on manual labour or hand-crafted characteristics, which may be costly and time-consuming. Convolutional neural networks (CNNs) have been frequently employed for road detection due to their capacity to automatically learn characteristics from data. In this research, we provide Modified LinkNet for the extraction of road features from high-resolution remote-sensing images. The proposed model incorporates several variables resulting in superior performance compared to current cutting-edge road detection techniques. SpaceNet road detection dataset yields 0.81 mIoU, which is approximately 0.1, 0.11, and 0.03 mIoU greater than U-net, DeeplabV3+, and LinkNet, respectively (base architecture). In addition, the training of the model enables more efficient inference making our method applicable to real-time applications and are therefore a more effective and efficient solution for the extraction of road features from remote sensing images.
Maritime logistics research by authors based in South Asian institutions: a systematic review
Authors: Weerasinghe B. A. , Perera H. N.
Published: March 2023

Systematic reviews improve future research by providing an overall picture of how research is conducted in a particular field. As a result, they are growing in number. As South Asia emerges as a geopolitical and maritime hub, attention must be shifted to maritime logistics in the region. This study examines how authors based in South Asian institutes contribute to maritime logistics research by way of a systematic review. It indicates that most research on maritime logistics in South Asia comes from India. Presenting the formulation of networks between authors and countries, the study reveals four research clusters that are derived based on the paper pool systematically derived through Scopus: i) Container terminal optimization, ii) Logistics activities in the hinterland, iii) Geopolitics in the maritime supply chain, and iv) Maritime transport. The evolution of South Asian maritime logistics is discussed based on the four clusters so derived. Moreover, the way that authors based in South Asia and their institutions have contributed journal articles in maritime logistics is discussed. Directions for future studies in maritime logistics in South Asia are introduced. We find that more collaborations can enhance the region’s maritime logistics research. Future studies may focus on industry academia and horizontal-vertical collaborations.
MASP3 Deficiency in Mice Reduces but Does Not Abrogate Alternative Pathway Complement Activity Due to Intrinsic Profactor D Activity
Authors: Gullipalli Damodar , Miwa Takashi , Golla Madhu , Sato Sayaka , Angampalli Sree , Song Wen-Chao
Published: March 2023

Complement factor D (FD) is a rate-limiting enzyme of the alternative pathway (AP). Recent studies have suggested that it is synthesized as an inactive precursor and that its conversion to enzymatically active FD is catalyzed by mannan-binding lectin-associated serine protease 3 (MASP3). However, whether MASP3 is essential for AP complement activity remains uncertain. It has been shown that Masp1/3 gene knockout did not prevent AP complement overactivation in a factor H–knockout mouse, and a human patient lacking MASP3 still retained AP complement activity. In this study, we have assessed AP complement activity in a Masp3-knockout mouse generated by CRISPR/Cas9 editing of the Masp1/3 gene. We confirmed specific Masp3 gene inactivation by showing intact MASP1 protein expression and absence of mature FD in the mutant mice. Using several assays, including LPS- and zymosan-induced C3b deposition and rabbit RBC lysis tests, we detected plasma concentration–dependent AP complement activity in Masp3 gene–inactivated mice. Thus, although not measurable in 5% plasma, significant AP complement activity was detected in 20–50% plasma of Masp3 gene–inactivated mice. Furthermore, whereas FD gene deletion provided more than 90% protection of CD55/Crry-deficient RBCs from AP complement-mediated extravascular hemolysis, Masp3 gene deletion only provided 30% protection in the same study. We also found pro-FD to possess intrinsic catalytic activity, albeit at a much lower level than mature FD. Our data suggest that MASP3 deficiency reduces but does not abrogate AP complement activity and that this is explained by intrinsic pro-FD activity, which can be physiologically relevant in vivo.
A prospective randomized study to evaluate the efficacy of pressure support ventilation with and without positive end expiratory pressure for preoxygenation in adult patients
Authors: Taxak Susheela , Gupta Mohini , Bala Renu , Govil Vasudha , Lallar Anushmita
Published: March 2023

A primary concern for anesthesiologists is the maintenance of oxygenation during general anesthesia. Extending the safe apnea time, which is the time from the onset of apnea until the oxygen saturation concentration reaches 90% or less, increases the margin of safety with tracheal intubation. Preoxygenation before anesthetic induction has been a widely accepted manoeuver to increase oxygen reserves and hence delay the onset of arterial desaturation during apnea. This study aimed to evaluate the efficacy of pressure support ventilation with/without positive end-expiratory pressure (PEEP) for preoxygenation in adult patients. A total of 132 patients, aged 20 to 50 years, scheduled for elective surgery under general anesthesia, requiring endotracheal intubation, were included and randomly divided into three groups (n = 44 per group): spontaneous ventilation (SV), pressure support ventilation without PEEP (PS), and pressure support ventilation with PEEP (PEEP) groups. In the SV group, the patients breathed spontaneously without any support using a face mask; in the PS group, the patients breathed spontaneously with the inspiratory pressure support of 12 cm H2O without PEEP; and in the PEEP group, the patients were subjected to preoxygenation (similar to the PS group) with PEEP at 6 cm H2O. Preoxygenation was terminated when the fraction of expired oxygen reached 90% and the duration was recorded. Time from 90 seconds after administration of rocuronium bromide until oxygen saturation fell to 93% was recorded and taken as safe apnea time. The time taken for preoxygenation (the expired oxygen fraction reaches 90) was significantly shorter in patients of PEEP and PS groups when compared to the SV group. The safe apnea time was significantly longer in patients of PEEP and PS groups compared with the SV group. Application of inspiratory pressure support of 12 cm H2O and PEEP of 6 cm H2O during preoxygenation significantly reduces the preoxygenation time and prolongs the safe apnea time compared with conventional preoxygenation.
In Vitro Investigation of Insulin-Like Growth Factor-I and Mechano-Growth Factor on Proliferation of Neural Stem Cells in High Glucose Environment
Authors: Gürbüz Tuğba Aydintug , Güleç Çağri , Toprak Fatih , Toprak Selin Fulya , Sozer Selcuk
Published: March 2023

Objective:

High glucose levels cause metabolic and vascular complications by affecting the nervous system with an increased risk of stroke and seizures. There are still no effective treatment modalities for the high morbidity and mortality rates detected in such situations. Neural stem cells (NSCs) provide neurogenesis in the nervous system, but high glucose is detrimental to NSCs. This study investigates the intrinsic and extrinsic effects of the growth factors insulin-like growth factor-I (IGF-I) and mechano-growth factor (MGF) on NSCs when exposed to high glucose levels. Thus, the possibility of new treatment options for diabetes patients is explored.

Materials and Methods:

Rat NSCs grown in cell culture conditions were exposed to a control glucose concentration of 17.5 mM and high concentrations of 27.75, 41.75, and 83.75 mM for 24 h. The high glucose concentrations were designed to recapitulate the in vivo conditions of diabetes mellitus, diabetic ketoacidosis, and hyperglycemia hyperosmolar status. Then, 0.2 μg/ml IGF-I and MGF growth factors were separately added and their expressions in the NCSs investigated by real-time reverse transcription-polymerase chain reaction. The effects of exogenous IGF-I and MGF administration on NSC proliferation under high glucose conditions were measured by BrdU incorporation assay using flow cytometry analysis.

Results:

A significant increase was detected in the relative gene expression fold changes of IGF-I and MGF in the NSCs. The MGF relative fold change was greater than the IGF-I for each high glucose condition. NSCs exposed to 27.75 mM glucose revealed a 17-fold and 40-fold increase in the IGF-I and MGF gene expressions, respectively; the 41.75 mM glucose similarly revealed 68-and 161-fold increases and the 83.75 mM glucose 75-and 137-fold increases. Exogenous IGF-I administration increased its expression profile, while the administration of MGF lowered its expression. The NSC was in the growth (G0/G1) phase of the cell cycle during the 24 h culture time. The percentage of proliferated NSC decreased to 89% (17.5 mM), 85% (27.75 mM), 50.30% (41.75 mM), and 28.97% (83.75 mM). Surprisingly, the increase in both IGF-I and MGF saved the NSCs from cell death.

Conclusion:

Exogenous IGF-I and MGF administrations via high glucose environments increased NSC proliferation at the time of injury and protected the NSCs from cell death. The neuroprotective effect of MGF was greater than that of IGF-I. Thus, due to their neurogenesis potential, exogenous IGF-I and MGF could be applied in the treatment of diabetes patients to relieve neural damage.
The Relationship between Transversus Abdominis and Internal Oblique Thickness and Disease-Related Characteristics in Parkinson's Disease
Authors: Aktar Burcin , Ozyurek Seher , Goz Evrim , Colakoglu Berril Donmez , Balci Birgul
Published: March 2023

Background and Aim:

The core muscles are essential for spinal stability during functional activities. Trunk muscle function is affected by specific neurodegenerative processes of Parkinson's disease (PD). This study aimed to investigate whether changes in transversus abdominis (TrA) and internal oblique (IO) thickness during the abdominal drawing-in maneuver (ADIM) were associated with clinical manifestations, core endurance, and functional mobility in patients with PD.

Materials and Methods:

We included patients with a modified Hoehn and Yahr staging of 3 or lower. TrA and IO muscle thickness were measured using ultrasound both at rest and during ADIM, and the percent change (%) was calculated to assess TrA and IO activation. Patients performed core endurance (prone bridge and sit-ups) and functional mobility tests (timed “up and go” [TUG] and five times sit-to-stand [FTSTS]). All assessments were conducted during the “on” phase.

Results:

Five female and 17 male patients were included in this study. We found a statistically significant correlation between ultrasound parameters of IO and the clinical manifestations of PD (P < 0.05). Correlations were observed between TrA percent change and prone bridge, sit-ups, TUG, and FTSTS (P < 0.05).

Conclusion:

To the best of our knowledge, this is the first ultrasound imaging-based study to demonstrate the relationship between TrA and IO muscle thickness and clinical outcomes, and functional performance in patients with PD. Percentage changes in IO were associated with the clinical manifestations of PD. Increased activation of TrA during ADIM was associated with improved core endurance and mobility. The results suggest that a trunk-specific exercise program may be the cornerstone in the treatment of PD-related changes.
Evaluation of Eosinophil-to-Lymphocyte Ratio before and after Immunotherapy in Pediatric Allergic Rhinitis Patients
Authors: Yenigun Alper , Dagistanli Nurtac , Polat Emre , Dogan Remzi , Nursoy Mustafa Atilla , Ozturan Orhan
Published: March 2023

Objective:

The aim of this study is to calculate the eosinophil-to-lymphocyte ratio (ELR) before and after the treatment with subcutaneous immunotherapy (SCIT) and to investigate if ELR decreases after the treatment. The results will support our hypothesis of using the ELR as a diagnostic and prognostic parameter in allergic rhinitis (AR) patients.

Study Design:

This study was planned and performed as a case–control study.

Materials and Methods:

In this prospective study, we have collected the data from 68 pediatric patients (aged between 9 and 18 years) who have been treated with 4-year SCIT and whose skin prick test was negative after treatment of AR. ELRs were compared based on the hemogram results before SCIT and approximately 4 years later. Patients who have the inflammatory disease were eliminated from the study since lymphocytes were increased in the blood biochemistry tests.

Results:

When the eosinophil counts were compared before and after the immunotherapy, it was observed that the eosinophil ratios were decreased from 7.14 ± 4.63 to 4.55 ± 2.98; (P = 0.000) after treatment. Lymphocyte count also decreased from 34.8 ± 10.3 to 32.9 ± 8.3 (P = 0.091). After SCIT, ELRs were significantly lower (P < 0.001). While the mean ± standard deviation (SD) value of ELR was 0.18 (0–0.66) before the treatment, the mean ± SD value after SCIT was 0.11 (0.01–0.67). Total immunoglobulin E decreased from 96.9 ± 10 to 82 ± 11, which was not statistically significant (P = 0.058).

Conclusion:

A statistically significant decrease in ELR was observed in patients whose skin prick test was negative after immunotherapy. ELR would be as valuable as a skin prick test for diagnostic and prognostic purposes.
Effect of Vaccination on Coronavirus Disease 2019-Related Olfactory Dysfunction
Authors: Alhazmi Abdulaziz , Darraj Hussam , Aqeel Abdulrahman , Khormi Ghadah , Hakami Alshomokh , Kariri Abdulaziz , Siddiq Afnan , Sahli Ali , Othathi Rahaf , Sumaily Ibrahim
Published: March 2023

Background:

Hyposmia and anosmia are the reduced ability and inability to perceive odors, respectively. Coronavirus disease 2019 (COVID-19) is caused by a novel coronavirus that was first detected in late 2019 in China and has spread globally since mid-February 2020. Olfactory dysfunction (OD), such as anosmia or hyposmia, is an important early indicator of COVID-19.

Objective:

This study aimed to compare the incidence and duration of COVID-19-related hyposmia before and after vaccination.

Design:

This was cross-sectional study.

Setting:

Jazan region, February–July 2022.

Patients and Methods:

Data were collected from the adult population of the Jazan region using a self-administered questionnaire in the Arabic language. Data are presented as frequencies and percentages for categorical variables. Analysis of variance was used to compare means between groups while the Chi-square test was used for the comparison of categorical variables. Statistical significance was set at P < 0.05.

Main Outcome Measures:

The incidence and duration of COVID-19-related OD before and after vaccination.

Sample Size:

The sample size was 466.

Results:

Of the 510 respondents, 466 met the study criteria. OD just after receiving the vaccines was reported by 53 (12.2%) participants. COVID-19 was confirmed in 268 participants (52.5%; 118 men and 150 women); of these, 163 (60.8%) had OD and 144 (53.7%) reported taste dysfunction. OD was more frequent in women than in men (66.7% vs. 53.4%, P = 0.03) and was the only symptom in 10 respondents (3.7%). OD was less frequent in postvaccination infection (54.9% vs. 73.8%, P = 0.003). Moreover, the OD duration was significantly shorter in postvaccination COVID-19 infection (improvement in the 1st week, 66.3% vs. 33.9%, P = 0.001).

Conclusions:

Among patients with COVID-19, OD occurs less frequently in men and after vaccination, and the duration is shorter after vaccination.

Limitations:

This study was limited by the small sample size, cross-sectional design, and small number of respondents with common chronic diseases such as diabetes and hypertension.
Orbital metastasis of myxofibrosarcoma
Authors: Shoji Marissa K. , Stevens Shanlee M. , Ohana Oded , Clauss Kevin D. , Tang Vincent D. , Khzam Rayan Abou , Rosenberg Andrew E. , Dubovy Sander R. , Lee Wendy W.
Published: March 2023

Myxofibrosarcoma (MFS), a common sarcoma in adults, typically affects the extremities. Primary orbital involvement is uncommon, and orbital metastasis is exceedingly rare. We describe a case of orbital MFS due to metastasis and provide an updated literature review. A 56-year-old woman presented with 2 months of progressive right eye proptosis. Relevant history included left palmar MFS excised 2 years prior. Examination demonstrated proptosis and restriction in abduction of her right eye without optic nerve compromise. Imaging revealed a well-circumscribed right orbital mass. Initial biopsy showed glandular tissue with chronic inflammation without an evidence of malignancy. She subsequently developed worsening proptosis, complete ophthalmoplegia, and a new afferent pupillary defect. Repeat orbital excisional biopsy with deeper dissection demonstrated high-grade MFS consistent with metastasis. She underwent chemoradiation with resolution of her lesion. Literature review identified 12 previously reported cases of MFS, only two of which involved metastasis to the orbit and were associated with worse prognosis. This report highlights a rare case of orbital metastasis of MFS with high-grade features confirmed on histopathology and provides an updated literature review. Prompt diagnosis and complete removal of MFS located both systemically and in the orbit are essential due to the metastatic potential.
Removal of Pb2+ from industrial wastewater using activated carbon from Persea americana seed
Authors: Dunoyer Arnulfo Tarón , Carrillo Luis Enrique Guzmán , Castillo Fredy Colpas
Published: March 2023

Activated carbon is a material that has various environmental applications, such as the adsorption of metallic lead ions (Pb2+). It can be obtained from different plant species. In this research, the seed of Persea americana (Avocado- HASS variety) was obtained from local markets in the city of Cartagena to be used in the removal of Pb2+ from wastewater from the fishing industry. To obtain activated carbon, the seed was carbonized in a Terrigeno-brand clay oven, Model DB 1200. Orthophosphoric acid at 21% w/v was used as an activating agent. The residual water was characterized following the APHA specifications. The turbidity was determined by nephelometry in a Turbiquant 300 IR turbidimeter. The Pb2+ concentration was determined by atomic absorption spectroscopy in a Thermo Scientific iCE 3300 equipment. The chemical surface of the material was performed by Fourier transform infrared spectroscopy (FTIR). The carbons were morphologically characterized using a scanning electron microscope SEM (Jeol 5910LV), visualized at 15kV. A yield of 20.38% by mass of coal is achieved. The pores are of irregular size, ranging from 16.2 to 55.98 μm. 65% of Pb2+, turbidity (57.6%), color (57%), total solids (50.2%), as well as BOD (53.12%) and COD (36%) are removed, finding statistically significant differences in values at the 95% level of significance. The seed of Persea americana (HASS avocado) can serve as plant material to obtain an adsorbent material (activated carbon) and be used in the removal of Pb2+ from wastewater.

Keywords: activated carbon, adsorption, avocado seeds (HASS variety), Pb2+, removal.
Reuniting Humanity and the Cosmos in Barth's Theology: Natural Disasters and The Fall
Authors: Harold G. , Wallace L.
Published: March 2023

Using literature, this article argues that Karl Barth's (1886 –1968 CE) concept of an "assumed fall" could be helpful if applied to the cosmos and humanity. Barth's conception of the created order is that it is perfect exactly the way it is, natural disasters included. Further, the fall did not affect the creation. Barth does however argue for fallen humanity. Nevertheless, the fall is assumed in the Election of Jesus Christ. There was never a time in which humans did not need a Saviour. Barth, therefore, places a separation between humanity and the created order. A close reading of Romans 8 and a look at Christian interpretative tradition, argue for an inseparability between humankind and the cosmos. In other words, fallen humans live in a fallen cosmos, and redeemed humans will live in a redeemed universe. If Barth's concept of the assumed fall of humanity could be applied to the cosmos as well, then the concept could fit well within the traditional reading of Romans 8 and could be beneficial for scientific/theological engagement.
Afectividad y creatividad. La potencia (micro)política de la amistad en el colectivo teatral. El Clú del Claun
Authors: Suarez Marina
Published: March 2023

En los albores de la democracia en Buenos Aires, un grupo de jovencísimos estudiantes se encontraron en una búsqueda común de técnicas actorales diversas. Con edades y trayectorias diferentes se nuclearon en torno a una profesora de clown que traía nuevas enseñanzas, ideas y experiencias. Los lazos afectivos entre los jóvenes fueron afianzándose y, en las clases, comenzaron a gestarse situaciones, personajes, escenas y obras. La emergencia de un “nosotros” por fuera de las singularidades funcionó como un resguardo emocional que favoreció la creatividad en la intimidad de los encuentros y también en las calles donde presentaban sus números. Así ocuparon colectivamente un lugar vedado durante los años de dictadura militar: el espacio público. Este artículo explora, desde una metodología cualitativa y relacional, la historia de El Clú del Claun. Partiendo del giro afectivo, indaga en los vínculos entre los integrantes, las búsquedas que los unieron y las dinámicas afectivas que estuvieron en la génesis de la singularidad del grupo.
Inconmensurabilidad de los costos económicos, ecológicos y en la salud provocados por el Proyecto Integral Morelos
Authors: Luna-Nemecio Josemanuel
Published: March 2023

Con la vuelta del siglo XX al XXI, el neoliberalismo produjo un incremento en la construcción de diversos megaproyectos destinados a la generación de energía. Lo cual implicó una sobreexplotación de recursos naturales estratégicos como el agua y la producción de enfermos ambientales. En México, esta situación se tradujo en la construcción de diversas Centrales Termoeléctricas de Ciclo Combinado (CTCC) que han terminado por generar diversas afectaciones ambientales y sanitarias que exceden las supuestas bonanzas económicas que sus principales promotores auguraban. Tomando nota de lo anterior, el presente estudio abre con una exposición acerca de la geopolítica de las CTCC combinado en México, para después presentar a la CTCC que, como parte del Proyecto Integral Morelos (PIM), se ha construido en la comunidad de Huexca (Yecapixtla, Morelos). Se exponen los potenciales costos económicos, ecológicos y sanitarios de dicha megainfraestructura, dando cuenta a lo largo del artículo de la inconmensurabilidad de estos frente a los impactos y conflictividad socioambiental que se ha suscitado a partir de la construcción y eventual entrada en funcionamiento de la CTCC de Huexca. Se concluye abogando por una revaloración y balance acerca de los costos sociales y ambientales que implicaría el PIM respecto a las ganancias extraordinarias que se generaría, en el entendido de dicho balance toma en consideración la necesidad de crear condiciones de posibilidad para alcanzar soberanía nacional y la justicia socioambiental.
Salas, calles y pantallas como escenarios de memoria. Juicios de lesa humanidad y constelaciones de performance en Argentina
Authors: Perez Mariana Eva
Published: March 2023

Este artículo estudia cuatro intervenciones performáticas que de maneras diversas dan a conocer y problematizan el desarrollo de los juicios por crímenes de lesa humanidad en Argentina: Genocida suelto, de la Fuerza Artística de Choque Comunicativo (FACC), Cuarto intermedio, de Félix Bruzzone y Monica Zwaig, y las declaraciones testimoniales en sede judicial de la escritora Raquel Robles y de la cantante y compositora Malena D’Alessio. Por medio del análisis de una performance de calle, otra de sala y dos testimonios que concluyeron con sendos asaltos performáticos sobre la escena judicial, se exploran las estrategias desplegadas para implicar a nuevas audiencias en la búsqueda activa de justicia. En particular, se indaga en los afectos que las mismas buscan movilizar y en las posibilidades de transmisión de las memorias que pueden habilitar distintos tipos de performances.
Casas y cosas aferradas a la memoria. Afectos y violencia política en Proyecto Villa
Authors: Donoso Pinto Catalina
Published: March 2023

El presente artículo examina los procedimientos del montaje teatral Proyecto Villa (2019) a cargo de Daniela Contreras y Edison Cajas, para explorar los modos en que se elabora una memoria de la violencia política a partir de ciertos objetos recolectados y una disposición espacial que reconstruye lugares en los que se practicó la tortura por parte de los aparatos de represión. Proyecto Villa se origina como una investigación en torno a centros de detención y tortura y propone una “instalación escénica” en la que ciertas convenciones de la escena tradicional se desafían para construir una experiencia para el/la espectador/a que se vuelve observador/a y participante de un espacio, a la vez que de una memoria viva encarnada en lo inanimado. Para analizar esta obra, este trabajo recurre a algunas de las ideas propuestas por los nuevos materialismos, las teorías de los afectos, una subjetividad poshumana y la noción de documentalidad. En la investigación se observarán dos de las principales estrategias de la puesta en escena de Proyecto Villa: la recolección y disposición de los objetos, por una parte, y la organización de los espacios, por otra. El texto busca poner en relevancia los mecanismos de la ficción puestos en juego al trabajar con materiales documentales, buscando describir estos procedimientos desde una propuesta de subjetividad material que se elabora a partir de los postulados teóricos antes singularizados, en diálogo con la idea de imaginación material.
Good Practice Regulatory Change
Authors:   Ipsos UK, Wilson Sophie , Cameron Daniel , Roff Ben
Published: March 2023

he Food Standards Agency (FSA) is responsible for food safety across England, Wales, and Northern Ireland. As part of its work on the Achieving Business Compliance (ABC) programme, the FSA wanted to understand more about how other regulators have approached regulatory change programmes, with a view to introducing their own programme. The FSA wanted to learn from what had happened in the past, explore the current landscape of regulatory change, and identify what good practice looks like. The ABC team also wanted to understand the challenges and barriers faced by other regulators and how these were dealt with, so they could learn more about what works. The overarching aim of the research was to identify transferable lessons learnt, and good practice in regulatory change. In particular, this focused on exploring: the planning and implementation of change stakeholder engagement and relationships outcomes and lessons learned The scope of the research was not restricted to the food landscape and included a broad range of regulators with a focus on, but not restricted to, those who operate within an inspection, safety and standards environment.
Investigation of Social Studies Teachers’ Attitudes towards Democracy and Multicultural Education
Authors: ÖZTÜRK Durdane , ERGÜL Seda
Published: March 2023

People from many different cultures have been living together in the world. Accordingly, multiculturalism has brought some problems. Education has a distinctive place in the resolution of these problems. Within this context, it is important to explore social studies teachers’ attitudes towards democracy and multicultural education, which is a significant element of education. The purpose of this study was to reveal social studies teachers’ attitudes towards democracy and multicultural education. In this survey and causal-comparative study, participants were composed of 332 social studies teachers. The data were collected using the “Democracy and Multicultural Education Attitude Scale”, which was developed by Toraman et al. (2015). The analyses involved Mann-Whitney U and Kruskal-Wallis H tests, frequency (f), percentage (%), and mean scores (X̅). The results revealed that social studies teachers’ attitudes towards democracy and multicultural education were positive. Teachers’ attitudes were positive in the dimension of prejudiced attitude towards multicultural education while they obtained more positive scores in the dimensions of attitude towards multicultural education, attitude towards democracy education, attitude towards democracy, and attitude towards cultural differences. Social studies teachers’ overall attitudes did not differ significantly by their years of experience, educational level, branch, gender, and geographical region of their schools. There were significant differences in teachers’ scores obtained from dimensions of attitude towards democracy education, attitude towards democracy, and attitude towards cultural differences in terms of educational level in favor of teachers with bachelor’s degrees. On the other hand, teachers with 1-5 years of experience had significantly higher scores from the dimension of prejudiced attitude towards multicultural education.
A Suggestion for Combating Digital Addiction: An Interdisciplinary Collaborative Intervention Model (CoDAIM)
Authors: AYDIN Betül , SEFEROĞLU S. Sadi
Published: March 2023

Digital addiction is a type of addiction that is showing itself with increasing momentum, particularly among teenagers and university students, compared to previous generations. Digital addiction (DA) is considered a problem that threatens individuals' life quality, physiological, psychological health and academic life. There are known and still unexplored psycho-social causes of this phenomenon. Individuals can encounter wide variety of risk and threat factors when they are intensely interacting with digital technologies. Similarly, some individuals can exhibit problematic behaviors in these environments. In this context, there are various proposed solutions with proven effectiveness in the literature for addressing digital addiction. In this study, a comprehensive literature review was conducted focusing on these proposed solutions and concluded that a holistic and collaborative approach is needed. Considering this need, semi-structured interviews were conducted with 12 experts from five different areas who have conducted academic research (psychiatry, clinical psychology, psychological counseling and guidance, instructional design, and digital security) on the roles and responsibilities of stakeholders in the digital addiction intervention model. As a result of the study, an interdisciplinary collaborative model against digital addiction was proposed. The model also includes suggestions for stakeholders and arguments. As a result of this study, a new perspective was brought to the digital addiction intervention process and proposals for intervention stages were developed.
Synthesis, Characterization, and Biological Evaluation Of [1,2,4 ]-Triazole-3yl]Sulfanyl Acetamide Derivative
Authors: Hotta Santanu Kumar , Rout Sudhanshu Sekhar , Kumar Anjan
Published: March 2023

A significant portion of recent papers is in the field of Mercapto substituted Triazole moiety  received considerable attention in the literature.Characterization and Antibacterial activity against important medically Gram positive Bacteria likely Actinomyces, Clostridium, Mycobacterium, Strptococci, Staphylococci and Nocardia.Triazole is a class of N-Bridged  Heterocyclic compounds especially in Chemotherapy. Triazole moiety seems to be very small but 1,2,4-Triazole derivatives have wide range of potential antibacterial activities against drug-resistant pathogens.Hybridization shows a high potential to develop novel drugs,reduce toxicity,and improve Pharmacokinetic profiles.More effective antibacterial studies might be obtained by the hybridization of  1,2,4-Triazole  mercapto moiety. A number of clinically effective antibacterial drugs become more effective. Therefore, we shed, herein, more light on novel synthetic drug and its antibacterial activity.
REAPER MAN, TEACHER MAN: USING POPULAR CULTURE TO TEACH GRIT, MORTALITY AWARENESS, AND GOAL SETTING IN THE AGE OF ANXIETY
Authors: Von Goble Brant
Published: March 2023

Since the advent of low-cost modern media technologies (records, films, radio, television, and the internet), popular culture has both shaped and been shaped by complex economic, political, governmental, moral, and artistic concerns. Fear and anxiety and the human capacity to control, reduce, or induce them in others have been tools for influencing both individual and societal behaviours for far longer. At the juncture of these two are both opportunity and hazard. This paper will briefly consider the historical context of our current apprehensiveness and collective neuroticism from the early media age to the present and how anxiety has been used by significant power players and the nominally disadvantaged alike. It will then turn to the role of media technologies in distorting our understanding of risk, mortality, and the potential for (and the sustainability and importance of) happiness. Finally, it will present a series of suggestions to produce more resilient, realistic, and goal-oriented learners by cultivating within them a robust understanding of their mortality, the inevitability of suffering, and the tenuousness of the human condition. Much of the material and culture referenced will be from the United States; however, the observations and suggestions throughout this paper should be broadly applicable to the peoples of the developed world. Finally, this paper will include ample content and conversational suggestions, examinations of media context and interpretations, and questions for classroom discussion for the teacher who wishes to guide students towards a better-grounded mental state.

 

 Article visualizations:
TEACHER INSIGHTS ON POLLUTION
Authors: Akar Elif , Genç Hasan
Published: March 2023

The aim of this research is to determine the level of information and awareness for the environment of teachers who are working in the schools in Gonen district of Isparta. The study group of the research consists of 16 volunteer teachers, 6 science sciences and 10 classroom teachers, who work in the schools in Gonen district of Isparta. As a research model, a descriptive research method was used from qualitative research methods. The research uses a semi-structured interview form developed by the researcher as a data collection tool. The semi-structured interview form contains a total of 9 questions. Descriptive analysis and content analysis were used to analyze data from the semi-structured interview form applied in the research. According to the research findings, teachers have no deep knowledge of the diversity of environmental pollution. It is seen that teachers are emphasizing physical and environmental pollution that they create superficially when talking about the presence of factories in the region. It was concluded that the source of livelihood was on agricultural activity and that the agricultural drugs used reduced the soil efficiency. To preserve the natural structure in the region, the village and the city can be conscious of students and teachers. Plans and projects can be designed under a heading to reduce environmental pollution. Social activities related to the environment can be organized to promote the natural beauty of the region.
 

 Article visualizations: