bluuebunny/crossref_metadata_2025 huggingface dataset:
Mathematical Modeling Study of Pressure Loss in the Flow Channels of Additive Manufacturing Aviation Hydraulic Valves
Authors: Li Dongfei , Dai Ning , Wang Hongtao , Zhang Fujun
Published: February 2023

The application of additive manufacturing in the field of aviation hydraulics greatly improves the design freedom of hydraulic valve internal flow channels. Pressure loss in hydraulic valve internal flow channels is a primary factor that designers need to consider, and the rapid prediction of pressure loss is very helpful for flow channel design. At present, most studies only focus on how much the pressure loss in an additive manufacturing (AM) hydraulic channel is reduced compared with an original hydraulic channel, and a mathematical model of pressure loss in an AM curved channel is still lacking. In this paper, the pressure loss in a curved flow channel was firstly studied, and the main parameters affecting the pressure loss were determined using the dimensionless analysis method. Using computational fluid dynamics simulation, the relationships between the flow channel diameter, the flow channel length, the flow channel curvature radius, the fluid velocity and pressure loss were studied. According to the multiple regression analysis method, the mathematical model of pressure loss in aviation hydraulic channels was developed, and the model was solved based on the orthogonal experimental results. The pressure loss in the flow channel samples fabricated using selective laser melting was tested, and the results showed that the average error between the test results and the mathematical model calculation results was 7.72%. This model can be used to quickly predict the pressure loss in curved flow channels in the aviation hydraulic field.
Environmental Hazards and Risk Identification in the Arctic Shelf Development as Part of China and Russia Energy Interests
Authors: Razmanova Svetlana , Pisarenko Zhanna , Nesterova Olga , Toan Nguyen Kahn , Ivanov Leonid
Published: February 2023

China and Russia have different interests in the Arctic but are forced to look for possible ways of cooperation in energy projects in the current external conditions. This changes the priorities of both countries and, accordingly, transforms the risks. Objectives of the research: to build an algorithm for identifying anthropogenic environmental risks in the context of two major players economic activities in the Arctic region: the Russian Federation and China. In the paper, we formulated an algorithm of environmental risk identification. We identified environmental hazards from the main parameter—the type of economic activity for the extraction of energy resources, premises, and factors for the occurrence of environmental hazards and compiled criteria for risk selection. Methods used: complex analysis (mixed method research): empirical and comparative methods, methods of expert assessments, the method of inductive statistics (inferential statistics) to compare the perception of risk at the level of different groups. Results: the algorithm has been formed for determining risks in the changed external conditions. Major anthropogenic environmental risks are identified from the perspective of the main players in the Arctic—Russia and China, which can help to make the necessary decisions on time and partially prevent environmental degradation. This makes it possible to identify the risks associated with conducting economic activities for the extraction of energy resources in the Arctic region. Therefore, this study contributes to a more accurate identification of anthropogenic environmental risks in the Arctic region.
On the Hydrothermal Behavior of Fluid Flow and Heat Transfer in a Helical Double-Tube Heat Exchanger with Curved Swirl Generator; Impacts of Length and Position
Authors: Mousavi Ajarostaghi Seyed Soheil , Hashemi Karouei Seyed Hossein , Alinia-kolaei Mehdi , Ahmadnejad Karimi Alireza , Mohammad Zadeh Morteza , Sedighi Kurosh
Published: February 2023

The hydrothermal behavior in a helical double-tube heat exchanger is numerically estimated. A new type of swirl generator with two sections, including; outer curved blades and a semi-conical section with two holes in the inner section, is employed. Two geometrical factors, containing the length (L1) and the position of the swirl generator (S), are used for investigation. The calculations were performed by a commercial FVM code, ANSYS FLUENT 18.2. The numerical outcomes show that a shorter length of the swirl generator leads to a better hydrothermal behavior. Accordingly, the model with L1 = 100 mm at m˙ = 0.008 kg/s achieves the maximum thermal performance by about 17.65, 53.85, and 100% enhancement compared to the models L1 = 200, 300 mm, and without swirl generator. Among the different studied positions of the swirl generator, the maximum heat transfer coefficient and average Nusselt number in entire mass flow rates belong to the case with position S = 0.3π mm. Moreover, the thermal performance of the case with S = 0.3π mm is higher than cases with S = 0.1π mm, S = 0.5π mm, and without swirl generator by about 11.11, 53.84, and 100%, respectively.
Using Machine Learning in Electrical Tomography for Building Energy Efficiency through Moisture Detection
Authors: Kłosowski Grzegorz , Hoła Anna , Rymarczyk Tomasz , Mazurek Mariusz , Niderla Konrad , Rzemieniak Magdalena
Published: February 2023

Wet foundations and walls of buildings significantly increase the energy consumption of buildings, and the drying of walls is one of the priority activities as part of thermal modernization, along with the insulation of the facades. This article discusses the research findings of detecting moisture decomposition within building walls utilizing electrical impedance tomography (EIT) and deep learning techniques. In particular, the focus was on algorithmic models whose task is transforming voltage measurements into spatial EIT images. Two homogeneous deep learning networks were used: CNN (Convolutional Neural Network) and LSTM (Long-Short Term Memory). In addition, a new heterogeneous (hybrid) network was built with LSTM and CNN layers. Based on the reference reconstructions’ simulation data, three separate neural network algorithmic models: CNN, LSTM, and the hybrid model (CNN+LSTM), were trained. Then, based on popular measures such as mean square error or correlation coefficient, the quality of the models was assessed with the reference images. The obtained research results showed that hybrid deep neural networks have great potential for solving the tomographic inverse problem. Furthermore, it has been proven that the proper joining of CNN and LSTM layers can improve the effect of EIT reconstructions.
Rationale for Parameters of Energy-Saving Illumination inside Agricultural Premises and Method of Its Values Calculation
Authors: Dovlatov Igor , Yuferev Leonid , Pavkin Dmitriy , Panchenko Vladimir , Bolshev Vadim , Yudaev Igor
Published: February 2023

High-quality lighting of premises in the cultivation of farm animals is an important condition for the successful development of the agro-industrial complex. Sufficient lighting with the simulation of sunrise and sunset which increases daylight hours to 15–16 h can raise the level of production by 8–15%. The most innovative, economical and efficient light source for livestock, poultry and greenhouse buildings are LED lamps allowing for a short payback period. The difference between the models developed by the authors and the traditional point method is taking into account lamp length o, lamp suspension height, location of the illuminated area under the lamp at displacement and observation angles, and luminous flux of light source, and the most important thing is body angle of the light source. This paper presents the method for calculating illumination under the LED lamp due to the large error in the values obtained by theoretical methods due to the lack of a correction factor for changing the illumination of the lamp (0.8). Prediction of crystal heating was carried out by verification calculation in the ANSYS/CFX software package. Forecasting the illumination of the fodder table was carried out by calculation in the DIALux evo software package. The main parameters of an energy-saving LED lamp (power consumption, luminous flux, color temperature and color) were selected. The consumption of electrical energy decreased by 85%; the average level of illumination increased and amounted to 123.1 lux. The developed method for calculating the illumination under the LED lamp can be considered satisfactory, the Student and Fisher criteria do not exceed tabular values and the correlation coefficient showed a close relationship. To comply with electrical safety standards in the premises, a resonant power supply system for LED lamps is offered.
Assessing the Role of Financial Incentives in Promoting Eco-Friendly Houses in the Lisbon Metropolitan Area—Portugal
Authors: Koengkan Matheus , Fuinhas José Alberto , Radulescu Magdalena , Kazemzadeh Emad , Alavijeh Nooshin Karimi , Santiago Renato , Teixeira Mônica
Published: February 2023

This article investigates the impact of fiscal and financial incentives for energy efficiency labels on eco-friendly houses (houses with high energy efficiency certificates, such as A+, A, B, and B−) in 18 municipalities in the Lisbon metropolitan region during the period 2014–2020. The empirical results indicate that the variables of fiscal incentive policies for energy efficiency labels, income per capita, credit agreements for the purchase or construction of a house, and the number of completed dwellings in new constructions for family housing encourage eco-friendly houses. In contrast, the variable number of completed reconstructions per 100 completed new constructions has a negative impact. Although this study is constrained by data limitations resulting from the short period under analysis and the moderate number of municipalities available, it advances the discussions around energy efficiency in residential properties in Portugal. Furthermore, it investigates the effectiveness of tax incentive policies for energy efficiency seals as an instrument for promoting ecological houses in the municipalities of the Lisbon metropolitan area. Thus, the need to study the Portuguese capital stands out as it is the most populous city in the country and concentrates a large part of the economic activity.
The Possible Outcomes of Poor Adherence to Conventional Treatment in Patients with X-Linked Hypophosphatemic Rickets/Osteomalacia
Authors: Zukeran Hiroaki , Ikegawa Kento , Numakura Chikahiko , Hasegawa Yukihiro
Published: February 2023

X-linked hypophosphatemic rickets/osteomalacia is an inherited disease caused by the loss of function in PHEX. Elevated plasma FGF23 in patients with XLH leads to hypophosphatemia. The conventional treatment for XLH, consisting of oral phosphate and active vitamin D, is often poorly adhered to for various reasons, such as the requirement to take multiple daily doses of phosphate. Burosumab, an anti-FGF23 antibody, is a new drug that directly targets the mechanism underlying XLH. We report herein three adult patients with poor adherence to the conventional treatment. In Patient 1, adherence was poor throughout childhood and adolescence. The treatment of Patients 2 and 3 became insufficient after adolescence. All of the patients suffered from gait disturbance caused by pain, fractures, and lower extremity deformities early in life. We prescribed burosumab for the latter two patients, and their symptoms, which were unaffected by resuming conventional treatment, dramatically improved with burosumab. Maintaining adherence to the conventional treatment is crucial but challenging for patients with XLH. Starting burosumab therapy from childhood or adolescence in pediatric patients with poor adherence may help prevent the early onset of complications.
Fermented (By Monascus purpureus or Aspergillus oryzae) and Non-Fermented Defatted Soybean Flour Extracts: Biological Insight and Mechanism Differences in Inflammatory Pain and Peritonitis
Authors: Manchope Marília F. , Bertozzi Mariana M. , Borghi Sergio M. , Handa Cíntia L. , Queiroz-Cancian Mariana A. , Ferraz Camila R. , Mizokami Sandra S. , Badaró-Garcia Stephanie , Andrade Ketlem C. , Zaninelli Tiago H. , Spinosa Wilma A. , Georgetti Sandra R. , Ida Elza I. , Verri Waldiceu A. , Casagrande Rubia
Published: February 2023

Background: Monascus purpureus and Aspergillus oryzae have been used to ferment defatted soybean flour (DSF: DSFF-Mp and DSSF-Ao, respectively) extract, improving antioxidant availability and conversion of the glycosylated isoflavones to aglycones. The aim of the present study was to evaluate the biological activity of fermented and non-fermented DSF extracts in pain and inflammation, which has not yet been explored. Methods: Phenolic compounds of extracts were determined. Non-fermented DSF (DSF-Non), DSFF-Mp, and DSFF-Ao (10–100 mg/kg) were administrated i.p., 30 min before i.pl. or i.p. carrageenan stimulus. Mechanical and thermal hyperalgesia, edema, histopathology, leukocyte recruitment, and oxidative stress in the paw tissue, and inflammatory cell recruitment, NFκB activation, and cytokine production were assessed in the peritoneum. Stomach and kidney toxicity were evaluated. Results: DSF-Non, DSFF-Mp, and DSFF-Ao extracts inhibited mechanical and thermal hyperalgesia, paw edema, histopathology, neutrophil recruitment, and oxidative stress, as well as inhibited peritoneal leukocyte recruitment. DSF-Non increased IL-10, and DSFF-Ao reduced IL-33 levels. DSFF-Mp increased IL-10 and reduced IL-33 production, and NFκB activation in CD45+ cells, without inducing toxicity. Conclusions: The present data reveal for the first time that fermented/non-fermented DSF extracts are analgesic and anti-inflammatory, showing differences in the mechanism of action depending on fungi applied for fermentation.
Optimization of the Circular Experimental Channel for PIV Measurements of Internal Aerodynamic Cases
Authors: Pulec Jaroslav , Dančová Petra , Novosád Jan
Published: February 2023

This paper deals with the design of an experimental circular channel model specially adapted for particle image velocimetry (PIV) measurements of airflow. The goal is to find a simple, fast, and functional approach for creating experimental models. The issue of the required PIV signal quality is defined, and the limits of acquiring relevant PIV data in the interior of circular channels are described, primarily as reflections of direct and scattered laser light caused by light passage through the cylindrical wall. As part of the experiment, measurements of reflections were made on differently coated surfaces of a plexiglass plate. Samples of various combinations of black matt spray, Rhodamine 6G coating, and roughened surface were created. From the presented results, a combination of black matt spray with a layer of Rhodamine 6G spray paint was chosen. The selected modification was further used for the internal modification of the experimental channel surface. Furthermore, a geometry modification to prevent light spread through the tube material is described. Data obtained from measurements before and after channel modification are presented and explained.
Foodborne Diseases in the Edible Insect Industry in Europe—New Challenges and Old Problems
Authors: Gałęcki Remigiusz , Bakuła Tadeusz , Gołaszewski Janusz
Published: February 2023

Insects play a key role in European agroecosystems. Insects provide important ecosystem services and make a significant contribution to the food chain, sustainable agriculture, the farm-to-fork (F2F) strategy, and the European Green Deal. Edible insects are regarded as a sustainable alternative to livestock, but their microbiological safety for consumers has not yet been fully clarified. The aim of this article is to describe the role of edible insects in the F2F approach, to discuss the latest veterinary guidelines concerning consumption of insect-based foods, and to analyze the biological, chemical, and physical hazards associated with edible insect farming and processing. Five groups of biological risk factors, ten groups of chemical risk factors, and thirteen groups of physical risks factors have been identified and divided into sub-groups. The presented risk maps can facilitate identification of potential threats, such as foodborne pathogens in various insect species and insect-based foods. Ensuring safety of insect-based foods, including effective control of foodborne diseases, will be a significant milestone on the path to maintaining a sustainable food chain in line with the F2F strategy and EU policies. Edible insects constitute a new category of farmed animals and a novel link in the food chain, but their production poses the same problems and challenges that are encountered in conventional livestock rearing and meat production.
Hemp Flour Particle Size Affects the Quality and Nutritional Profile of the Enriched Functional Pasta
Authors: Bonacci Sonia , Di Stefano Vita , Sciacca Fabiola , Buzzanca Carla , Virzì Nino , Argento Sergio , Melilli Maria Grazia
Published: February 2023

The rheological and chemical quality of pasta samples, which were obtained using the durum wheat semolina fortified with the hemp seed solid residue, after oil extraction, sieved at 530 μm (Hemp 1) or 236 μm (Hemp 2) at different percentages of substitution (5%, 7.5%, and 10%, were evaluated. The total polyphenolic content in hemp flour was quantified in the range of 6.38–6.35 mg GAE/g, and free radical scavenging was included in the range from 3.94–3.75 mmol TEAC/100 g in Hemp 1 and Hemp 2, respectively. The phenolic profiles determined by UHPLC-ESI/QTOF-MS showed that cannabisin C, hydroxycinnamic and protocatechuic acids were the most abundant phenolic compounds in both hemp flours. Among the amino acids, isoleucine, glutamine, tyrosine, proline, and lysine were the most abundant in raw materials and pasta samples. Although the hemp seeds were previously subjected to oil extraction, hemp flours retain about 8% of oil, and the fatty acids present in the largest amount were linoleic acid and α-linolenic acid. Characterization of the minerals showed that the concentration of macro and trace elements increased according to fortification percentage. Sensory evaluation and cooking quality indicated that the best performance in terms of process production and consumer acceptance was obtained using Hemp 2 at 7.5%. Hemp supplementation could be a potential option for producing high-quality, nutritionally rich, low-cost pasta with good color and functionality.
Evaluation of Processing Conditions and Hydrocolloid Addition on Functional Properties of Aquafaba
Authors: Crawford Kaelyn , Tyl Catrin , Kerr William
Published: February 2023

Aquafaba, the cooking water from chickpeas, could replace animal-derived ingredients such as egg whites in systems that require the stabilization of an oil or gas phase. However, little is known about how processing methods and additives affect its functional properties. In this study, aquafaba was prepared via boiling or pressure-cooking at water-to-seed (WSR) ratios of 5:1, 4:1 and 3:1. The effects of preparation method and pH adjustment on viscosity, protein content, solubility and profile were evaluated. Samples were further analyzed for foaming capacity/stability (FC/FS) and emulsifying activity/stability index (EAI/ESI). Foams were also prepared in combination with xanthan gum or hydroxypropyl methylcellulose (HPMC). Solubility was lowest near pH 4 and not affected by cooking method and protein profile was not affected by method or ratio. Samples with pH 3 had high EAI and FS, but low ESI and FC. WSR did not significantly affect interfacial properties. Xanthan gum had a greater effect than HPMC on viscosity and prevented foam liquid drainage for 24 h. While the preparation method affects aquafaba properties, subsequent pH adjustment is of greater relevance for interfacial properties. Foam volumes can be maximized and foam drainage limited by appropriate choice of hydrocolloids and addition levels.
Structural Insights on Hyp-Gly-Containing Peptides as Antiplatelet Compounds through Topomer CoMFA and CoMSIA Analysis
Authors: Yang Yijie , Tian Qi , Li Shiming , Li Bo
Published: February 2023

Increasing evidence has shown collagen hydrolysate involves a variety of bioactivities. In our previous study, multiple antiplatelet peptides containing Hyp/Pro-Gly were identified in collagen hydrolysates from Salmo salar and silver carp skin and exhibited anti-thrombosis activity without bleeding risks in vivo. However, the relationship between structure and activity remains unknown. We performed 3D-QSAR studies on 23 Hyp/Pro-Gly-containing peptides in which 13 peptides were reported before. CoMFA, Topomer CoMFA and CoMSIA analyses were used to generate the QSAR models. Topomer CoMFA analysis showed a q2 value of 0.710, an r2 value of 0.826, an r2pred value of 0.930, and the results showed that Hyp instead of Pro was more important for improving the antiplatelet activity. CoMSIA analysis showed a q2 value of 0.461, an r2 value of 0.999, and an r2pred value of 0.999. Compared with the electrostatic field and hydrogen bond donor field, the steric field, hydrophobic field and hydrogen bond receptor field have great influence on the activity of antiplatelet peptides. The predicted peptide EOGE exhibited antiplatelet activity induced by ADP, and inhibited thrombus formation (300 μmol/kg bw) without bleeding risks. Combined results of these studies indicate that OG-containing peptides had a potential to be developed into an effective specific medical food in the prevention of thrombotic diseases.
Optimization of Supercritical Carbon Dioxide Extraction of Polyphenols from Black Rosehip and Their Bioaccessibility Using an In Vitro Digestion/Caco-2 Cell Model
Authors: Kasapoğlu Kadriye Nur , Kruger Johanita , Barla-Demirkoz Aslı , Gültekin-Özgüven Mine , Frank Jan , Özçelik Beraat
Published: February 2023

The fruits of Rosa pimpinellifolia are rich sources of (poly)phenols, however they are underutilized due to the limited information available. The influence of the pressure, temperature, and co-solvent concentration (aqueous ethanol) of the supercritical carbon dioxide extraction (SCO2-aqEtOH) on the extraction yield, total phenolic-, total anthocyanin-, catechin-, cyanidin-3-O-glucoside contents, and total antioxidant activity of black rosehip was investigated simultaneously. The maximum obtained total phenolic and total anthocyanin contents under the optimized extraction conditions (280 bar, 60 °C and 25% ethanol, v/v) were 76.58 ± 4.25 mg gallic acid equivalent and 10.89 ± 1.56 mg cyanidin-3-O-glucoside equivalent per g of the dry fruits, respectively. The optimal extract obtained by SCO2-aqEtOH was compared to two other extraction procedures: ultrasonication using ethanol as solvent (UA-EtOH) and pressurized hot water extraction (PH-H2O). The bioaccessibility and cellular metabolism of the phenolic compounds in the different black rosehip extracts were assessed using an in vitro digestion coupled with a human intestinal Caco-2 cell model. The in vitro digestive stability and cellular uptake of the phenolic compounds had no significant difference among the different extraction methods. The results of this study confirm the efficiency of SCO2-aqEtOH extraction for phenolic compounds and, in particular, for anthocyanins, and could be used to produce new functional food ingredients from black rosehip with high antioxidant power containing both hydrophilic and lipophilic compounds.
Waste Orange Peels as a Feed Additive for the Enhancement of the Nutritional Value of Tenebrio molitor
Authors: Kotsou Konstantina , Chatzimitakos Theodoros , Athanasiadis Vassilis , Bozinou Eleni , Adamaki-Sotiraki Christina , Rumbos Christos I. , Athanassiou Christos G. , Lalas Stavros I.
Published: February 2023

Lately, additional attention is being placed on edible insects, since they constitute an excellent, cost-efficient source of proteins with a low ecological footprint. Tenebrio molitor was the first insect that was considered edible by EFSA in 2021. This species can replace conventional protein sources and thus, it has the potential to be used in many different food products. In the present study, a food by-product that is commonly produced (i.e., albedo orange peel waste) was used as a feed additive for T. molitor larvae, in an effort to further improve the circular economy and enhance the nutritional value of the insects. To this end, bran, which is commonly used as feed for T. molitor larvae, was fortified with the albedo orange peel waste (up to 25% w/w). Larval performance, in terms of larval survival and growth, as well as the larval nutritional value, i.e., the content of protein, fat, carbohydrates, ash, carotenoids, vitamins A and C, and polyphenols, was evaluated. Based on the results, the increase in the percentage of orange peel albedos in T. molitor feed resulted in a subsequent increase in the content of larvae in carotenoids and vitamin A up to 198%, in vitamin C up to 46%, and an increase in the protein and ash content up to 32% and 26.5%, respectively. Therefore, the use of albedo orange peel waste for feeding of T. molitor larvae is highly recommended, since it results in larvae with enhanced nutritional value and at the same time, the utilization of this feeding substrate further lowers the cost of insect farming.
Variations in the Metabolome of Unaged and Aged Beef from Black-and-White Cows and Heifers by 1H NMR Spectroscopy
Authors: Bischof Greta , Januschewski Edwin , Witte Franziska , Terjung Nino , Heinz Volker , Juadjur Andreas , Gibis Monika
Published: February 2023

(1) Background: The selection of raw material and the postmortem processing of beef influence its quality, such as taste. In this study, the metabolome of beef from cows and heifers is examined for differences during aging. (2) Methods: Thirty strip loins from eight heifers and seven cows (breed code: 01–SBT) were cut into ten pieces and aged for 0, 7, 14, 21 and 28 days. Samples from the left strip loins were wet-aged in vacuum, while samples from right strip loins were dry-aged at 2 °C and 75% relative humidity. The beef samples were extracted with methanol–chloroform–water, and the polar fraction was used for 1H NMR analysis. (3) Results: The PCA and OPLS-DA showed that the metabolome of cows and heifers varied. Eight metabolites revealed significant differences (p < 0.05) in the samples from cows and heifers. The aging time and aging type of beef also affected the metabolome. Twenty-eight and 12 metabolites differed significantly (p < 0.05) with aging time and aging type, respectively. (4) Conclusions: The variations between cows and heifers and aging time affect the metabolome of beef. By comparison, the influence of aging type is present but less pronounced.
The Effect of Decreased Ca++/Mg++ ATPase Activity on Lactobacillus delbrueckii subsp. bulgaricus sp1.1 Survival during Spray Drying
Authors: Sun Jialei , Cai Wenjing , Wang Yu , Niu Haiyue , Chen Xi , Han Xue
Published: February 2023

Compared with the commonly used technique of freeze-drying, spray drying has lower energy costs. However, spray drying also has a fatal disadvantage: a lower survival rate. In this study, the survival of bacteria in a spray-drying tower decreased as the water content was reduced. The water content of 21.10% was the critical point for spray drying Lactobacillus delbrueckii subsp. bulgaricus (L. bulgaricus) sp1.1 based on sampling in the tower. Based on the relationship between the moisture content of spray drying and the survival rate, the water content of 21.10% was also the critical point for the change in the survival rate during spray drying. Proteomic analysis was used to investigate the reasons for L. bulgaricus sp1.1 inactivation during and after spray drying. Gene Ontology (GO) enrichment revealed that differentially expressed proteins were mainly associated with the cell membrane and transport. In particular, proteins related to metal ion transport included those involved in the transport of potassium, calcium and magnesium ions. The protein–protein interaction (PPI) network revealed that Ca++/Mg++ adenosine triphosphatase (ATPase) may be a key protein. Ca++/Mg++ ATPase activity decreased substantially during spray drying (p < 0.05). Supplementation with Ca++ and Mg++ significantly increased the expression of ATPase-related genes and enzyme activity (p < 0.05). The Ca++/Mg++ ATPase activity of L. bulgaricus sp1.1 was enhanced by increasing the intracellular Ca++ or Mg++ concentration, thus increasing the survival of spray-dried LAB. Bacterial survival rates were increased to 43.06% with the addition of Ca++ and to 42.64% with the addition of Mg++, respectively. Ca++/Mg++ ATPase may be the key to the damage observed in spray-dried bacteria. Furthermore, the addition of Ca++ or Mg++ also reduced bacterial injury during spray drying by enhancing the activity of Ca++/Mg++ ATPase.
Use of Heat-Shock and Edible Coating to Improve the Postharvest Preservation of Blueberries
Authors: Liu Chunyan , Ding Jie , Huang Peng , Li Hongying , Liu Yan , Zhang Yuwei , Hu Xinjie , Deng Shanggui , Liu Yaowen , Qin Wen
Published: February 2023

The quality of blueberry fruit is easily altered after harvest. We investigated the regulatory mechanism of heat-shock (postharvest treatment) and edible coating (preharvest treatment) on the post-harvest physiological quality of blueberry from the perspective of physiological, biochemical and organoleptic characteristics. In our research, the optimal TKL concentration and the appropriate range of heat-shock temperatures were first screened based on actual application results, and then a combination of heat-shock temperature and TKL coating with significant differences in preservation effects was selected to investigate the effects of different heat-shock temperatures and TKL60 composite coating on post-harvest quality and volatile compound concentration of blueberries under refrigerated conditions. Our results showed that TKL with 60 mg/L thymol can retard the development of the degree of membrane lipid peroxidation and effectively reduce the incidence of fruit decay and the severity of blueberries infected with major pathogens at 25 °C. Meanwhile, heat-shock treatments were effective in maintaining the quality of blueberries, with a certain advantage from 45 °C to 65 °C after 8 d of storage at ambient temperature, but these treated groups were slightly inferior to TKL60 groups for fresh-keeping effect. Remarkably, the combination of heat-shock treatment and edible coating application could extend the shelf life of blueberries by 7–14 d compared to the results obtained with coating alone under low temperature storage. Specifically, heat treatment at 45 °C for 60 min after TKL60 coating (HT2) retarded the decrease in the levels of ascorbic acid, total anthocyanin, total acid and soluble solids. Gas chromatography–mass spectrometry hierarchical clustering analysis showed that this treatment also improved the aroma of the fruit, which maintained a certain similarity with that of fresh blueberries after 14 d. Principal component analysis (PCA) of the results of the evaluations carried out using an electronic nose (E-nose) and electronic tongue (E-tongue) showed that blueberries of the HT2 treated group did not show a large placement change of the PC1 distribution area from that of the fresh and blank control group. Accordingly, the combination of coating with heat-shock treatment can effectively improve the post-harvest quality and aroma compound concentration of blueberries, showing good application potential in storage and preservation of fresh fruits such as blueberries.
Cost of Recommended Diet (CoRD) and Its Affordability in Bangladesh
Authors: Islam Saiful , Nowar Abira , Amin Md. Ruhul , Shaheen Nazma
Published: February 2023

The cost of diet has been recognized as a major determinant of overall diet quality and nutritional outcomes. We aimed to estimate the minimum cost and affordability of the recommended diet based on the updated food-based dietary guidelines (FBDG) in Bangladesh. To compute the cost of the recommended diet (CoRD), we collected retail prices of foods corresponding to each of the food groups in the latest Bangladeshi FBDG. For affordability, the household size and daily food expenditure data were used from the most recent Household Income and Expenditure survey (HIES). The CoRD was calculated based on the average number of servings recommended for each food group; the CoRD was adjusted by a deflation factor and divided by the household’s daily food expenditure to estimate affordability. We found that the CoRD was $0.87 (83 BDT) per person per day at the national level. Nationally, about 43% of households could not afford the CoRD, with rural areas bearing a disproportionate share of the burden. We also found households to overspend on starchy staples while underspending on protein-rich foods, fruits, and dairy. These findings highlight the need for immediate implementation of interventions to improve the affordability of the CoRD and redesign policy instruments to create a sustainable food system.
The Colección Osteológica Subactual de Santiago: Origin and Current State of a Documented Skeletal Collection from Chile, Latin America
Authors: Meza-Escobar Ofelia , Galimany Jacqueline , González-Oyarce Rocío , Barreaux Höpfl Nicole
Published: February 2023

This manuscript aims to introduce the Colección Osteológica Subactual de Santiago (COSS), a documented skeletal collection from Santiago, Chile, consisting of 1635 individuals living in low socioeconomic areas of the capital during the late 19th and early 20th centuries. The origin and current state of this collection, as well as the process by which it came to be housed at the University of Chile, is described. As of today, after long efforts for further documentation and improvements on the physical conditions of the collection, biological sex and age-at-death has been documented through burial records for 1198 individuals. Largely studied by Chilean researchers and students, the COSS collection has enabled a great amount of research, while also serving as part of a thriving scholarly community from different disciplines. Finally, discussion around representativeness, legal status and ethical concerns are addressed, highlighting the specific issues faced when working and studying the COSS collection.
Robust Localization for Near- and Far-Field Signals with an Unknown Number of Sources
Authors: Liu Tao , Feng Hao , Qiu Tianshuang , Luan Shengyang , Zhang Jiacheng
Published: February 2023

Source location is a constant issue of importance of both theoretical study and practical engineering. Many pioneers have put out the corresponding solutions for near- or far-field signals, and preferred contributions are suggested. To our best knowledge, there are currently few focused approaches to the complicated situation where both near- and far-field signals exist with an unknown number of sources. Additionally, the robustness of the method must be taken into account when the additive background noise does not follow Gaussian or super-Gaussian distribution. To solve these problems, a novel method based on phased fractional lower-order moment (PFLOM) is proposed to simultaneously better preserve the signal and suppress the noise. Secondly, the whole procedure of the method containing direction of arrival (DOA) estimation, range estimation, separation of near-and far-field sources, and crucial parameter settings are studied in detail. Finally, comprehensive Monte Carlo experiments are carried out in the simulation to demonstrate the superiority of the proposed method compared to the existing competitive methods. Due to the novel method’s effectiveness with an unknown number of sources and robustness against various noises, it is believed that it could be fully utilized in more fields.
Jet Feedback in Star-Forming Galaxies
Authors: Krause Martin G. H.
Published: February 2023

In this paper, I review our understanding of how jet feedback works in star-forming galaxies. There are some interesting differences to radiative feedback from Active Galactic Nuclei (AGN). Jets act on galaxy haloes as well as on dense gas, for example in regularly rotating discs, where they can suppress star formation (particularly in the centre, negative feedback), but also enhance it (positive feedback). Jet feedback may produce turbulent, multi-phase gas structures where shocks contribute to the ionisation and is observed in connection with galactic outflows. The exact driving mechanism of these outflows is still unclear, but may be a combination of effects linked to star formation, jet-induced turbulence and radiative AGN feedback. Supermassive black holes in any galaxy can produce jets. Preferential radio detections in more massive galaxies can be explained with different conditions in the circumgalactic medium and, correspondingly, different jet–environment interactions.
Phosphonation of Alginate–Polyethyleneimine Beads for the Enhanced Removal of Cs(I) and Sr(II) from Aqueous Solutions
Authors: Salih Khalid A. M. , Zhou Kanggen , Hamza Mohammed F. , Mira Hamed , Wei Yuezhou , Ning Shunyan , Guibal Eric , Salem Waheed M.
Published: February 2023

Although Cs(I) and Sr(II) are not strategic and hazardous metal ions, their recovery from aqueous solutions is of great concern for the nuclear industry. The objective of this work consists of designing a new sorbent for the simultaneous recovery of these metals with selectivity against other metals. The strategy is based on the functionalization of algal/polyethyleneimine hydrogel beads by phosphonation. The materials are characterized by textural, thermo-degradation, FTIR, elemental, titration, and SEM-EDX analyses to confirm the chemical modification. To evaluate the validity of this modification, the sorption of Cs(I) and Sr(II) is compared with pristine support under different operating conditions: the pH effect, kinetics, and isotherms are investigated in mono-component and binary solutions, before investigating the selectivity (against competitor metals) and the possibility to reuse the sorbent. The functionalized sorbent shows a preference for Sr(II), enhanced sorption capacities, a higher stability at recycling, and greater selectivity against alkali, alkaline-earth, and heavy metal ions. Finally, the sorption properties are compared for Cs(I) and Sr(II) removal in a complex solution (seawater sample). The combination of these results confirms the superiority of phosphonated sorbent over pristine support with promising performances to be further evaluated with effluents containing radionuclides.
Prevalence of Metabolic Syndrome among Apparently Healthy Adult Population in Pakistan: A Systematic Review and Meta-Analysis
Authors: Adil Syed Omair , Islam Md Asiful , Musa Kamarul Imran , Shafique Kashif
Published: February 2023

Background: Metabolic syndrome (MetS) is considerably higher worldwide. It varies greatly in different populations geographically and based on criteria used to diagnose the disease. This review was conducted to determine the prevalence of MetS among apparently healthy adults of Pakistan. A systematic review was performed on Medline/PubMed, SCOPUS, ScienceDirect, Google Scholar, and Web of Science databases until July 2022. Articles published on Pakistani healthy adult population reporting MetS were included. Pooled prevalence was reported with 95% confidence interval (CI). Of 440 articles, 20 articles met the eligibility. Results: The pooled prevalence of MetS was 28.8% (95% CI: 17.8–39.7). The maximum prevalence was from a sub-urban village of Punjab (68%, 95% CI: 66.6–69.3) and Sindh province (63.7%, 95% CI: 61.1–66.3). International Diabetes Federation guidelines had shown 33.2% (95% CI: 18.5–48.0) whereas National Cholesterol Education Program guidelines showed 23.9% (95% CI: 8.0–39.8) prevalence of MetS. Furthermore, individuals with low high-density lipoprotein (HDL) 48.2% (95% CI: 30.8–65.6), central obesity 37.1% (95% CI: 23.7–50.5), and high triglyceride 35.8% (95% CI: 24.3–47.3) showed higher prevalence. Conclusion: A considerably higher prevalence of MetS was observed among apparently healthy individuals in Pakistan. High triglyceride, low HDL, and central obesity were found as significant risk factors. (Registration # CRD42022335528)
Relationship between Locomotive Syndrome and Musculoskeletal Pain and Generalized Joint Laxity in Young Chinese Adults
Authors: Ma Yixuan , Wu Xinze , Shen Shaoshuai , Hong Weihao , Qin Ying , Sun Mingyue , Luan Yisheng , Zhou Xiao , Zhang Bing
Published: February 2023

This study aims to investigate the prevalence of locomotive syndrome (LS) and to examine the relationship of LS with musculoskeletal symptoms (pain, generalized joint laxity (GJL)) in young Chinese adults. Our study population (n = 157; mean age of 19.8 ± 1.2 years) comprises college student residents at Tsinghua University in Beijing, China. Three screening methods were used to evaluate LS: 25-question Geriatric Locomotive Function Scale (GLFS-25), a two-step test, and a stand-up test. Musculoskeletal pain was assessed by self-report and visual analog scale (VAS), and joint body laxity was evaluated using the GJL test. The prevalence of LS was 21.7% of all participants. Musculoskeletal pain affected 77.8% of the college students with LS and was strongly associated with LS. A total of 55.0% of college students with LS had four or more site joints that were positive for GJL, and higher scores of GJL were associated with a higher prevalence rate of LS. Young Chinese college students have a relatively high prevalence of LS, and musculoskeletal pain and GJL were significantly related to LS. The present results suggest that we need early screening of musculoskeletal symptoms and LS health education in young adults to prevent the mobility limitations of LS in the future.
The Incidence and Risk Factors for Allogeneic Blood Transfusions in Pediatric Spine Surgery: National Data
Authors: Fercho Justyna , Krakowiak Michał , Yuser Rami , Szmuda Tomasz , Zieliński Piotr , Szarek Dariusz , Miękisiak Grzegorz
Published: February 2023

(1) Background: Pediatric spinal surgery is a blood-intensive procedure. In order to introduce a rational blood management program, identifying the risk factors for transfusions is mandatory. (2) Methods: Data from the national database covering the period from January 2015 to July 2017 were analyzed. The available data included the demographics, characteristics of the surgeries performed, length of stay, and in-house mortality. (3) Results: The total number of patients used for the analysis was 2302. The primary diagnosis was a spinal deformity (88.75%). Most fusions were long, with four levels or more (89.57%). A total of 938 patients received a transfusion; thus, the transfusion rate was 40.75%. The present study identified several risk factors; the most significant was a number of levels fused greater than 4 (RR 5.51; CI95% 3.72–8.15; p < 0.0001), followed by the deformity as the main diagnosis (RR 2.69; CI95% 1.98–3.65; p < 0.0001). These were the two most significant factors increasing the odds of a transfusion. Other factors associated with an increased risk of transfusion were elective surgery, the female sex, and an anterior approach. The mean length of stay in days was 11.42 (SD 9.93); this was greater in the transfused group (14.20 vs. 9.50; p < 0.0001). (4) Conclusions: The rate of transfusions in pediatric spinal surgery remains high. A new patient blood management program is necessary to improve this situation.
Stressed, Lonely, and Overcommitted: Predictors of Lawyer Suicide Risk
Authors: Krill Patrick R. , Thomas Hannah M. , Kramer Meaghyn R. , Degeneffe Nikki , Anker Justin J.
Published: February 2023

Suicide is a significant public health concern, and lawyers have been shown to have an elevated risk for contemplating it. In this study, we sought to identify predictors of suicidal ideation in a sample consisting of 1962 randomly selected lawyers. Using logistic regression analysis, we found that high levels of work overcommitment, high levels of perceived stress, loneliness as measured by the UCLA loneliness scale, and being male were all significantly associated with an increased risk of suicidal ideation. These results suggest that interventions aimed at reducing work overcommitment, stress, and loneliness, and addressing gender-specific risk factors, may be effective in reducing the risk of suicidal ideation among lawyers. Further research is needed to expand upon these findings and to develop and test interventions specifically tailored to the needs of this population.
Focus on Liability of Residences for Elderly and Sick People: A Case Series and Medico-Legal Issues
Authors: D’Anna Tommaso , Argo Antonina , Albano Giuseppe Davide , Puntarello Maria , Rizzo Chiara , Guadagnino Daniela , Zerbo Stefania
Published: February 2023

Residences for elderly and sick people, self-sufficient or dependent, are varied. To date, the liability profiles of these structures are not clearly delineated, and increasingly often, their operating and organization criteria are entrusted to subnational, regional, or local regulations. Among the various deficits, there is the keeping of a complete and detailed documentation/diary of the patient, the lack of which can generate medico-legal problems. In this paper, we present three cases of guests in residences for a dependent person brought to the attention of the Institute of Forensic Medicine of the University Hospital of Palermo due to criminal proceedings, where the lack of existing documentation in the structure and, in some cases, the behavior of the professionals working there, led the evaluator to deduce the organization’s culpability.
Induction of Labor in Women with Previous Cesarean Section and Unfavorable Cervix: A Retrospective Cohort Study
Authors: Germano Chiara , Mappa Ilenia , Cromi Antonella , Busato Enrico , Incerti Maddalena , Lojacono Andrea , Rizzo Giuseppe , Attini Rossella , Patrizi Lodovico , Revelli Alberto , Masturzo Bianca
Published: February 2023

Background: The efficacy and safety of a cervical ripening balloon (CRB) in women with a previous cesarean section (CS) and unfavorable Bishop score are still controversial. Methods: A retrospective cohort study was performed across six tertiary hospitals from 2015 to 2019. Women with one previous transverse CS, singleton cephalic term pregnancy and BS < 6 were included if submitted to labor induction with a CRB. The main outcome was the rate of vaginal birth after cesarean (VBAC) after CRB ripening. Secondary outcomes were abnormal composite fetal and maternal outcomes. Results: Of the 265 women included, 57.3% had successful vaginal birth. Augmentation improved vaginal delivery (32.2% vs. 21.2%). Intrapartum analgesia was associated with an increased VBAC rate (58.6% vs. 34.5%). Maternal BMI ≥30 and age ≥40 years increased emergency CS rate (11.8% vs. 28.3% and 7.2 vs. 15.9%). Composite adverse maternal outcome occurred in 4.8% of CRB group women and increased to 17.6% when associated with oxytocin. Uterine rupture occurred in one case (0.4%) in the CRB–oxytocin group. Poorer fetal outcome occurred after emergency CS, if compared to successful VBAC (12.4% vs. 3.3%). Conclusions: In women with a previous CS and unfavorable Bishop score, induction of labor with a CRB can be considered safe and effective.