bluuebunny/crossref_metadata_2025 huggingface dataset:
Figure S4 from Pattern-Specific Transcriptomics Identifies ASGR2 as a Predictor of Hematogenous Recurrence of Gastric Cancer
Authors: Tanaka Haruyoshi , Kanda Mitsuro , Miwa Takashi , Tanaka Chie , Kobayashi Daisuke , Umeda Shinichi , Shibata Masahiro , Suenaga Masaya , Hattori Norifumi , Hayashi Masamichi , Iwata Naoki , Yamada Suguru , Nakayama Goro , Fujiwara Michitaka , Kodera Yasuhiro
Published: April 2023

Effect of forced expression of ASGR2 on MKN1cell proliferation.
Figure S1 from Pattern-Specific Transcriptomics Identifies ASGR2 as a Predictor of Hematogenous Recurrence of Gastric Cancer
Authors: Tanaka Haruyoshi , Kanda Mitsuro , Miwa Takashi , Tanaka Chie , Kobayashi Daisuke , Umeda Shinichi , Shibata Masahiro , Suenaga Masaya , Hattori Norifumi , Hayashi Masamichi , Iwata Naoki , Yamada Suguru , Nakayama Goro , Fujiwara Michitaka , Kodera Yasuhiro
Published: April 2023

ASGR2 expression status of cancer wide cell lines and the status of co-regulated genes.
Supplementary Figure 6 from Radiation-Induced Malignant Transformation of Preneoplastic and Normal Breast Primary Epithelial Cells
Authors: Repullés Joan , Anglada Teresa , Soler David , Ramírez Juan Carlos , Genescà Anna , Terradas Mariona
Published: April 2023

Characterisation of acini formed in Matrigel 3D cultures
Supplementary Figure 5 from Radiation-Induced Malignant Transformation of Preneoplastic and Normal Breast Primary Epithelial Cells
Authors: Repullés Joan , Anglada Teresa , Soler David , Ramírez Juan Carlos , Genescà Anna , Terradas Mariona
Published: April 2023

Speed of movement of BPECs in 3D culture
Supplementary Figure 1 from Radiation-Induced Malignant Transformation of Preneoplastic and Normal Breast Primary Epithelial Cells
Authors: Repullés Joan , Anglada Teresa , Soler David , Ramírez Juan Carlos , Genescà Anna , Terradas Mariona
Published: April 2023

Anchorage assay analysis
Supplementary Data from Radiation-Induced Malignant Transformation of Preneoplastic and Normal Breast Primary Epithelial Cells
Authors: Repullés Joan , Anglada Teresa , Soler David , Ramírez Juan Carlos , Genescà Anna , Terradas Mariona
Published: April 2023

Supplementary figure legends, tables and macro
Figure S1 from Epigenetic Silencing of THY1 Tracks the Acquisition of the Notch1–EGFR Signaling in a Xenograft Model of CD44+/CD24low/CD90+ Myoepithelial Cells
Authors: Montanari Micaela , Carbone Maria Rita , Coppola Luigi , Giuliano Mario , Arpino Grazia , Lauria Rossella , Nardone Agostina , Leccia Felicia , Trivedi Meghana V. , Garbi Corrado , Bianco Roberto , Avvedimento Enrico V. , De Placido Sabino , Veneziani Bianca Maria
Published: April 2023

see Legend
Supplementary Table S2 from Divergent Activity of the Pseudogene PTENP1 in ER-Positive and Negative Breast Cancer
Authors: Yndestad Synnøve , Austreid Eilin , Skaftnesmo Kai Ove , Lønning Per Eystein , Eikesdal Hans Petter
Published: April 2023

Genes with shared microRNA (miRNA) responsive elements (MREs) and corresponding miRNAs.
Supplementary Figure Legends from Divergent Activity of the Pseudogene PTENP1 in ER-Positive and Negative Breast Cancer
Authors: Yndestad Synnøve , Austreid Eilin , Skaftnesmo Kai Ove , Lønning Per Eystein , Eikesdal Hans Petter
Published: April 2023

Supplementary figure legends
Supplementary Figure 2 from Molecular Response to Neoadjuvant Chemotherapy in High-Grade Serous Ovarian Carcinoma
Authors: Arend Rebecca C. , Londoño Angelina I. , Montgomery Allison M. , Smith Haller J. , Dobbin Zachary C. , Katre Ashwini A. , Martinez Alba , Yang Eddy S. , Alvarez Ronald D. , Huh Warner K. , Bevis Kerri S. , Straughn J. Michael , Estes Jacob M. , Novak Lea , Crossman David K. , Cooper Sara J. , Landen Charles N. , Leath Charles A.
Published: April 2023

Flowchart depicting the number of patients in each step of the study.
Figure S2 from Inhibition of Aurora-A Promotes CD8+ T-Cell Infiltration by Mediating IL10 Production in Cancer Cells
Authors: Han Jing , Jiang Zhen , Wang Chennan , Chen Xin , Li Rongqing , Sun Na , Liu Xiangye , Wang Hui , Hong Li , Zheng Kuiyang , Yang Jing , Ikezoe Takayuki
Published: April 2023

Figure S2 shows the IL-10Ralpha mRNA levels in the control-treated or IL-10-treated CD8+ T cells.
Table S2 from Genomic Alterations Associated with Recurrence and TNBC Subtype in High-Risk Early Breast Cancers
Authors: Wilson Timothy R. , Udyavar Akshata R. , Chang Ching-Wei , Spoerke Jill M. , Aimi Junko , Savage Heidi M. , Daemen Anneleen , O'Shaughnessy Joyce A. , Bourgon Richard , Lackner Mark R.
Published: April 2023

FoundationOne sequencing data for n=399 breast cancer population. Each sheet contains a distinct type of alteration. The clinical covariates used in our analysis are included.
Figure S1 from The Tissue-Reconstructing Ability of Colon CSCs Is Enhanced by FK506 and Suppressed by GSK3 Inhibition
Authors: Ishida Ryo , Koyanagi-Aoi Michiyo , Oshima Nobu , Kakeji Yoshihiro , Aoi Takashi
Published: April 2023

Introduction of OCT3/4, KLF4 and SOX2 into SW480 using polycistronic vector.
Supplementary Figure 2 from S-Nitrosylation of EGFR and Src Activates an Oncogenic Signaling Network in Human Basal-Like Breast Cancer
Authors: Switzer Christopher H. , Glynn Sharon A. , Cheng Robert Y.-S. , Ridnour Lisa A. , Green Jeffrey E. , Ambs Stefan , Wink David A.
Published: April 2023

PDF file - 2.2MB, NO signaling results in PP2A-c phosphorylation and decreased phosphatase activity
Supplementary Figure 2 from The Hedgehog Receptor Patched Functions in Multidrug Transport and Chemotherapy Resistance
Authors: Bidet Michel , Tomico Amandine , Martin Patrick , Guizouarn Hélène , Mollat Patrick , Mus-Veteau Isabelle
Published: April 2023

PDF file - 839K, Resistance of hPtc-expressing yeasts depends on doxorubicin concentration
Supplementary Tables S1-S2 from Genome-Wide Analysis in a Murine Dnmt1 Knockdown Model Identifies Epigenetically Silenced Genes in Primary Human Pituitary Tumors
Authors: Dudley Kevin J. , Revill Kate , Whitby Philip , Clayton Richard N. , Farrell William E.
Published: April 2023

Supplementary Tables S1-S2 from Genome-Wide Analysis in a Murine Dnmt1 Knockdown Model Identifies Epigenetically Silenced Genes in Primary Human Pituitary Tumors
Figure S6 from Establishment of the First Well-differentiated Human Pancreatic Neuroendocrine Tumor Model
Authors: Benten Daniel , Behrang Yasmin , Unrau Ludmilla , Weissmann Victoria , Wolters-Eisfeld Gerrit , Burdak-Rothkamm Susanne , Stahl Felix R. , Anlauf Martin , Grabowski Patricia , Möbs Markus , Dieckhoff Jan , Sipos Bence , Fahl Martina , Eggers Corinna , Perez Daniel , Bockhorn Maximillian , Izbicki Jakob R. , Lohse Ansgar W. , Schrader Jörg
Published: April 2023

Liver metastasis model NT-3
Supplementary Figure 5 from Alpha-Melanocyte–Stimulating Hormone Suppresses Oxidative Stress through a p53-Mediated Signaling Pathway in Human Melanocytes
Authors: Kadekaro Ana Luisa , Chen Juping , Yang Jennifer , Chen Shuna , Jameson Joshua , Swope Viki B. , Cheng Tan , Kadakia Madhavi , Abdel-Malek Zalfa
Published: April 2023

PDF file - 364K, Down-regulation of p53 by shRNA and its effect on the expression of p21 in primary cultures of human melanocytes
Supplementary Figure 3 from Alpha-Melanocyte–Stimulating Hormone Suppresses Oxidative Stress through a p53-Mediated Signaling Pathway in Human Melanocytes
Authors: Kadekaro Ana Luisa , Chen Juping , Yang Jennifer , Chen Shuna , Jameson Joshua , Swope Viki B. , Cheng Tan , Kadakia Madhavi , Abdel-Malek Zalfa
Published: April 2023

PDF file - 1.7MB, DNA damage induced by UVR in the presence and absence of nutlin-3 as determined by gamma-H2AX immunofluorescence analyzed by flow cytometer
Supplementary Figure 2 from Alpha-Melanocyte–Stimulating Hormone Suppresses Oxidative Stress through a p53-Mediated Signaling Pathway in Human Melanocytes
Authors: Kadekaro Ana Luisa , Chen Juping , Yang Jennifer , Chen Shuna , Jameson Joshua , Swope Viki B. , Cheng Tan , Kadakia Madhavi , Abdel-Malek Zalfa
Published: April 2023

PDF file - 281K, Dose-dependent accumulation of p53 in human melanocytes induced by 18 h incubation with increasing concentrations of nutlin-3
Supplementary Table 1 from The Lymphotactin Receptor Is Expressed in Epithelial Ovarian Carcinoma and Contributes to Cell Migration and Proliferation
Authors: Kim Mijung , Rooper Lisa , Xie Jia , Rayahin Jamie , Burdette Joanna E. , Kajdacsy-Balla Andre A. , Barbolina Maria V.
Published: April 2023

PDF file - 58K, Sequences of primers used to detect expression of XCL1 and XCL2 by QPCR
Supplementary Table 1 from Disseminated Prostate Cancer Cells Can Instruct Hematopoietic Stem and Progenitor Cells to Regulate Bone Phenotype
Authors: Joseph Jeena , Shiozawa Yusuke , Jung Younghun , Kim Jin Koo , Pedersen Elisabeth , Mishra Anjali , Zalucha Janet Linn , Wang Jingcheng , Keller Evan T. , Pienta Kenneth J. , Taichman Russell S.
Published: April 2023

PDF file - 62K
Supplementary Figure Legends 1-8 from TLE1 Is an Anoikis Regulator and Is Downregulated by Bit1 in Breast Cancer Cells
Authors: Brunquell Chris , Biliran Hector , Jennings Scott , Ireland Shubha Kale , Chen Renwei , Ruoslahti Erkki
Published: April 2023

PDF file - 38K
Supplementary Figure 1 from The Signal Peptide of Mouse Mammary Tumor Virus-Env: A Phosphoprotein Tumor Modulator
Authors: Feldman Dafna , Roniger Maayan , Bar-Sinai Allan , Braitbard Ori , Natan Carmit , Love Dona C. , Hanover John A. , Hochman Jacob
Published: April 2023

PDF file - 515K, Members of the ErbB4 pathway. Genes found to be differentially expressed in one or more of the MCF-7 cell lines are shaded
Supplementary Materials and Methods from Lysine-Specific Demethylase 1 Mediates AKT Activity and Promotes Epithelial-to-Mesenchymal Transition in PIK3CA-Mutant Colorectal Cancer
Authors: Miller Samuel A. , Policastro Robert A. , Savant Sudha S. , Sriramkumar Shruthi , Ding Ning , Lu Xiaoyu , Mohammad Helai P. , Cao Sha , Kalin Jay H. , Cole Philip A. , Zentner Gabriel E. , O'Hagan Heather M.
Published: April 2023

Contains additional details on bioinformatic analyses, including references for packages used.
Supplementary Figures 1-11 from Diverse BRAF Gene Fusions Confer Resistance to EGFR-Targeted Therapy via Differential Modulation of BRAF Activity
Authors: Stangl Christina , Post Jasmin B. , van Roosmalen Markus J. , Hami Nizar , Verlaan-Klink Ingrid , Vos Harmjan R. , van Es Robert M. , Koudijs Marco J. , Voest Emile E. , Snippert Hugo J.G. , Kloosterman W.P.
Published: April 2023

S1. Impact of BRAF (fusion) gene expression on phosphorylation of AKT. S2. BRAF (fusion) gene mRNA and protein expression levels. S3. Phosphoproteomics screen in HEK293 cells reveals that BRAF fusions and BRAFV600E activate similar signaling pathways. S4. BRAF (fusion) gene expression and MAPK pathway activation in HEK293 cells. S5. BRAF (fusion) protein localization in HEK293 cells. S6. Establishment of optimal duration of dox induction for BRAF (fusion) protein expression. S7. Validation of phospho-proteins and transcriptomic analysis of BRAF (fusion) gene expressing P18T CRC organoid lines. S8. Expression of most differentially expressed genes in DLG1-BRAF expressing P18T organoids and CRC patients. S9. BRAF (fusion) genes confer resistance to EGFR inhibition. S10. Impact of afatinib exposure on pAKT levels in BRAF (fusion) gene expressing CRC organoids. S11. Differential sensitivities of BRAF (fusion) genes to combinatorial targeting of EGFR and MEK.
Supplementary Figure 2 from EpCAM Modulates NF-κB Signaling and Interleukin-8 Expression in Breast Cancer
Authors: Sankpal Narendra V. , Fleming Timothy P. , Gillanders William E.
Published: April 2023

PDF file - 78K, Varificition of EpCAM knockdown by two independent shRNA and rescue.
Supplementary Figure 1 from EpCAM Modulates NF-κB Signaling and Interleukin-8 Expression in Breast Cancer
Authors: Sankpal Narendra V. , Fleming Timothy P. , Gillanders William E.
Published: April 2023

PDF file - 108K, EpCAM and IL-8 microarray expression data from 1881 breast cancer plotted in box plot.
Supplementary Table 1 from Analysis of mRNA Profiles after MEK1/2 Inhibition in Human Pancreatic Cancer Cell Lines Reveals Pathways Involved in Drug Sensitivity
Authors: Gysin Stephan , Paquette Jesse , McMahon Martin
Published: April 2023

PDF file, 48K, Top 50 mRNAs most significantly correlated with MEK inhibitor insensitivity.
Supplementary Figure 1 from Analysis of mRNA Profiles after MEK1/2 Inhibition in Human Pancreatic Cancer Cell Lines Reveals Pathways Involved in Drug Sensitivity
Authors: Gysin Stephan , Paquette Jesse , McMahon Martin
Published: April 2023

PDF file, 42K, Generation and validation of a MEK inhibitor sensitivity classifier using support vector machine.
Supplemental Table 1 from Alternative NHEJ Pathway Components Are Therapeutic Targets in High-Risk Neuroblastoma
Authors: Newman Erika A. , Lu Fujia , Bashllari Daniela , Wang Li , Opipari Anthony W. , Castle Valerie P.
Published: April 2023

Supplemental Table 1: represents heterogeneity of NB tumors
Supplementary Figure 3 from Migfilin Regulates Esophageal Cancer Cell Motility through Promoting GSK-3β–Mediated Degradation of β-Catenin
Authors: He Huan , Ding Fang , Li Yi , Luo Aiping , Chen Hongyan , Wu Chuanyue , Liu Zhihua
Published: April 2023

PDF file - 43K
Supplementary Figure 7 from EWS/FLI1 Regulates EYA3 in Ewing Sarcoma via Modulation of miRNA-708, Resulting in Increased Cell Survival and Chemoresistance
Authors: Robin Tyler P. , Smith Anna , McKinsey Erin , Reaves Lisa , Jedlicka Paul , Ford Heide L.
Published: April 2023

PDF file - 652K, miR-708 increases apoptosis and sensitizes A673 Ewing's sarcoma cells to etoposide likely due to decreased DNA
Supplementary Figure 4 from The Heterochronic microRNA let-7 Inhibits Cell Motility by Regulating the Genes in the Actin Cytoskeleton Pathway in Breast Cancer
Authors: Hu Xiaowen , Guo Jinyi , Zheng Lan , Li Chunsheng , Zheng Tim M. , Tanyi Janos L. , Liang Shun , Benedetto Chiara , Mitidieri Marco , Katsaros Dionyssios , Zhao Xia , Zhang Youcheng , Huang Qihong , Zhang Lin
Published: April 2023

PDF file - 4531K, Fig. S4. let-7b inhibits motility in breast cancer cells.
Supplementary Video 1 from Basal-like Breast Cancer Cells Induce Phenotypic and Genomic Changes in Macrophages
Authors: Stewart Delisha A. , Yang Yinmeng , Makowski Liza , Troester Melissa A.
Published: April 2023

AVI file - 3MB, Movie of THP-1 cells engulfing latex microparticles after coculturing with MCF-7 luminal breast cancer cells.
Supplementary Figure 3 from Environmental Estrogens Differentially Engage the Histone Methyltransferase EZH2 to Increase Risk of Uterine Tumorigenesis
Authors: Greathouse K. Leigh , Bredfeldt Tiffany , Everitt Jeffrey I. , Lin Kevin , Berry Tia , Kannan Kurunthachalam , Mittelstadt Megan L. , Ho Shuk-mei , Walker Cheryl L.
Published: April 2023

PDF file - 1.6MB, (A) Activation of rapid non-genomic PI3K/AKT signaling in Sprague Dawley rats 0.5hr after a single exposure to doses of BPA shown. Western analysis and quantification of ratio of phospho-S6 to total S6 from a representative experiment (N=2) using tissues pooled from groups of 2-3 animals. (B) Quantification of induction of non-genomic PI3K/AKT signaling 6hr after exposure to 1mg/kg DES. (C) Western analysis to detect changes in H3K27me3 levels in the developing prostate in response to BPA demonstrating a reduction in H3K27me3 0.5hrs after exposure.
Supplementary Figure 2 from Expression of G Protein-Coupled Receptor 19 in Human Lung Cancer Cells Is Triggered by Entry into S-Phase and Supports G2–M Cell-Cycle Progression
Authors: Kastner Stefan , Voss Tilman , Keuerleber Simon , Glöckel Christina , Freissmuth Michael , Sommergruber Wolfgang
Published: April 2023

PDF file - 62K, Gpr19 siRNA-induced increase in the relative number of DMS 53 cells with G2/M DNA content
Supplementary Figure 4 from Exosomal Annexin II Promotes Angiogenesis and Breast Cancer Metastasis
Authors: Maji Sayantan , Chaudhary Pankaj , Akopova Irina , Nguyen Phung M. , Hare Richard J. , Gryczynski Ignacy , Vishwanatha Jamboor K.
Published: April 2023

Matrigel plug assay
Supplementary Figure 3 from Exosomal Annexin II Promotes Angiogenesis and Breast Cancer Metastasis
Authors: Maji Sayantan , Chaudhary Pankaj , Akopova Irina , Nguyen Phung M. , Hare Richard J. , Gryczynski Ignacy , Vishwanatha Jamboor K.
Published: April 2023

Angiogenic response
Supplemental Figures 1-7 from Bacterial SOS Genes mucAB/umuDC Promote Mouse Tumors by Activating Oncogenes Nedd9/Aurkb via a miR-145 Sponge
Authors: Tanooka Hiroshi , Inoue Ayako , Takahashi Ryou-u , Tatsumi Kouichi , Fujikawa Kazuo , Nagao Tetsuji , Ishiai Masamichi , Chiwaki Fumiko , Aoyagi Kazuhiko , Sasaki Hiroki , Ochiya Takahiro
Published: April 2023

Supplementary Fig. S1. Nedd9 and Aurkb seed match sequences in mucAB and umuDC.

Supplementary Fig. S2. Selection of cells expressing Tet-repressor protein.

Supplementary Fig. S3. Microarray analysis of deregulated oncogenes.

Supplementary Fig. S4. Suppression of cellular transformation with anti-mucAB shRNA.

Supplementary Fig. S5. Confirmation of interaction of miR-145 with anti-miR-145.

Supplementary Fig. S6. Microcolony formation over time.

Supplementary Fig. S7. Comparison of tumor incidence rates between males and females, and between presence and absence of Zn.
Supplementary Figure 6 from KRASG12D- and BRAFV600E-Induced Transformation of Murine Pancreatic Epithelial Cells Requires MEK/ERK-Stimulated IGF1R Signaling
Authors: Appleman Victoria A. , Ahronian Leanne G. , Cai JiuFeng , Klimstra David S. , Lewis Brian C.
Published: April 2023

PDF file - 415K, Combined inhibition of MEK and IGF1R reduces pancreatic cancer cell survival
Supplementary Figure 5 from KRASG12D- and BRAFV600E-Induced Transformation of Murine Pancreatic Epithelial Cells Requires MEK/ERK-Stimulated IGF1R Signaling
Authors: Appleman Victoria A. , Ahronian Leanne G. , Cai JiuFeng , Klimstra David S. , Lewis Brian C.
Published: April 2023

PDF file - 186K, Tumors formed by PDECs with IGF1R knockdown display normal IGF1R protein levels
Suppl. Figure Legends from Epigenetically Regulated Chromosome 14q32 miRNA Cluster Induces Metastasis and Predicts Poor Prognosis in Lung Adenocarcinoma Patients
Authors: González-Vallinas Margarita , Rodríguez-Paredes Manuel , Albrecht Marco , Sticht Carsten , Stichel Damian , Gutekunst Julian , Pitea Adriana , Sass Steffen , Sánchez-Rivera Francisco J. , Lorenzo-Bermejo Justo , Schmitt Jennifer , De La Torre Carolina , Warth Arne , Theis Fabian J. , Müller Nikola S. , Gretz Norbert , Muley Thomas , Meister Michael , Tschaharganeh Darjus F. , Schirmacher Peter , Matthäus Franziska , Breuhahn Kai
Published: April 2023

Suppl. Figure Legends
Supplementary Video 1 from Inhibition of Eg5 Acts Synergistically with Checkpoint Abrogation in Promoting Mitotic Catastrophe
Authors: Chen Yue , Chow Jeremy P.H. , Poon Randy Y.C.
Published: April 2023

AVI file - 436K
Supplementary Figure 2 from Inhibition of Eg5 Acts Synergistically with Checkpoint Abrogation in Promoting Mitotic Catastrophe
Authors: Chen Yue , Chow Jeremy P.H. , Poon Randy Y.C.
Published: April 2023

PDF file - 50K
Supplemental Figures 1 - 4 from Heparanase-Induced GEF-H1 Signaling Regulates the Cytoskeletal Dynamics of Brain Metastatic Breast Cancer Cells
Authors: Ridgway Lon D. , Wetzel Michael D. , Ngo Jason A. , Erdreich-Epstein Anat , Marchetti Dario
Published: April 2023

Supplemental Figure 1. A. Western blot of purified preparations of human latent and active HPSE recombinant proteins showing distinct molecular weights, β-actin was probed as a loading control. M.W. standards were run in parallel with samples (left lane). B. Dose-dependent inhibition of heparanase (A-HPSE) endoglycosidase activity by SST0001, a glycol-split, non - anticoagulant form of heparin (50, 51). The heparanase inhibitory activity and structural details of SST0001 has been described ( 50, 51). Aliquots of purified recombinant human active HPSE were treated with various concentrations of SST0001 (0, 1, 3, and 10 μg/μl,respectively) for 2 hr. at 37{degree sign}C. HPSE activity (U/ml) was then determined using the heparan sulfate degrading enzyme assay kit{trade mark, serif} (Takara, Inc.: cat # MK412) following manufacturer's protocol. Supplemental Figure 2. Western blot probed for GEF-H1 used to generate GEF-H1 knockdowns (fig. 4A). β-actin was probed as a loading control. Supplemental Figure 3. Gated populations from FACS demonstrating the selection of transduced high GFP - expressing 231BR3 cells. Supplemental Figure 4. 231BR3 GFP - expressing cells. A. 231BR3 scrambled control cells expressing GFP. B. 231BR3 GEF-H1 shRNA (clone 1) cells expressing GFP. C. 231BR3 GEF-H1 shRNA (clone 4) cells expressing GFP. Upper panel: brightfield images. Lower panel: GFP images.
Supplementary Table 2 from MYC-Induced Epigenetic Activation of GATA4 in Lung Adenocarcinoma
Authors: Castro Inês C. , Breiling Achim , Luetkenhaus Katharina , Ceteci Fatih , Hausmann Simone , Kress Sebastian , Lyko Frank , Rudel Thomas , Rapp Ulf R.
Published: April 2023

PDF file - 73K, Statistical significance of methylation percentage changes at GATA4 promoter upon MYC expression in A549 cells.
Supplementary Table S5 from Interactions with Fibroblasts Are Distinct in Basal-Like and Luminal Breast Cancers
Authors: Camp J. Terese , Elloumi Fathi , Roman-Perez Erick , Rein Jessica , Stewart Delisha A. , Harrell J. Chuck , Perou Charles M. , Troester Melissa A.
Published: April 2023

Supplementary Table S5 from Interactions with Fibroblasts Are Distinct in Basal-Like and Luminal Breast Cancers
Supplementary Figure S1 from Interactions with Fibroblasts Are Distinct in Basal-Like and Luminal Breast Cancers
Authors: Camp J. Terese , Elloumi Fathi , Roman-Perez Erick , Rein Jessica , Stewart Delisha A. , Harrell J. Chuck , Perou Charles M. , Troester Melissa A.
Published: April 2023

Supplementary Figure S1 from Interactions with Fibroblasts Are Distinct in Basal-Like and Luminal Breast Cancers
Supplementary Data from UNC45A Confers Resistance to Histone Deacetylase Inhibitors and Retinoic Acid
Authors: Epping Mirjam T. , Meijer Lars A.T. , Bos Johannes L. , Bernards René
Published: April 2023

Supplementary Data from UNC45A Confers Resistance to Histone Deacetylase Inhibitors and Retinoic Acid
Supplementary Table Legends 1-6, Figure Legend 1 from Phosphoproteomic Screen Identifies Potential Therapeutic Targets in Melanoma
Authors: Tworkoski Kathryn , Singhal Garima , Szpakowski Sebastian , Zito Christina Ivins , Bacchiocchi Antonella , Muthusamy Viswanathan , Bosenberg Marcus , Krauthammer Michael , Halaban Ruth , Stern David F.
Published: April 2023

Supplementary Table Legends 1-6, Figure Legend 1 from Phosphoproteomic Screen Identifies Potential Therapeutic Targets in Melanoma
Supplementary Data from Adhesive Interactions Regulate Transcriptional Diversity in Malignant B Cells
Authors: Nadav-Dagan Liat , Shay Tal , Dezorella Nili , Naparstek Elizabeth , Domany Eytan , Katz Ben-Zion , Geiger Benjamin
Published: April 2023

Supplementary Data from Adhesive Interactions Regulate Transcriptional Diversity in Malignant B Cells
Supplementary Figure 1 from Phosphoproteomic Screen Identifies Potential Therapeutic Targets in Melanoma
Authors: Tworkoski Kathryn , Singhal Garima , Szpakowski Sebastian , Zito Christina Ivins , Bacchiocchi Antonella , Muthusamy Viswanathan , Bosenberg Marcus , Krauthammer Michael , Halaban Ruth , Stern David F.
Published: April 2023

Supplementary Figure 1 from Phosphoproteomic Screen Identifies Potential Therapeutic Targets in Melanoma
Supplementary Table 1 from miR-31 Is a Broad Regulator of β1-Integrin Expression and Function in Cancer Cells
Authors: Augoff Katarzyna , Das Mitali , Bialkowska Katarzyna , McCue Brian , Plow Edward F. , Sossey-Alaoui Khalid
Published: April 2023

PDF file - 59K
Supplementary Data from p53-Dependent Induction of Prostate Cancer Cell Senescence by the PIM1 Protein Kinase
Authors: Zemskova Marina , Lilly Michael B. , Lin Ying-Wei , Song Jin H. , Kraft Andrew S.
Published: April 2023

Supplementary Figures S1-S5.
Supplementary Data from EZH2-Dependent Suppression of a Cellular Senescence Phenotype in Melanoma Cells by Inhibition of p21/CDKN1A Expression
Authors: Fan Tao , Jiang Shunlin , Chung Nancy , Alikhan Ali , Ni Christina , Lee Chyi-Chia Richard , Hornyak Thomas J.
Published: April 2023

Supplementary Figures S1-S7; Supplementary Table S1.
Supplementary Figures S1-S2 from The Retinoblastoma Protein Tumor Suppressor Is Important for Appropriate Osteoblast Differentiation and Bone Development
Authors: Berman Seth D. , Yuan Tina L. , Miller Emily S. , Lee Eunice Y. , Caron Alicia , Lees Jacqueline A.
Published: April 2023

Supplementary Figures S1-S2 from The Retinoblastoma Protein Tumor Suppressor Is Important for Appropriate Osteoblast Differentiation and Bone Development
Supplementary Figure 1 from miR-31 Is a Broad Regulator of β1-Integrin Expression and Function in Cancer Cells
Authors: Augoff Katarzyna , Das Mitali , Bialkowska Katarzyna , McCue Brian , Plow Edward F. , Sossey-Alaoui Khalid
Published: April 2023

PDF file - 20K
Supplementary Data from Nanoliposomal Short-Chain Ceramide Inhibits Agonist-Dependent Translocation of Neurotensin Receptor 1 to Structured Membrane Microdomains in Breast Cancer Cells
Authors: Heakal Yasser , Kester Mark
Published: April 2023

Supplementary Data from Nanoliposomal Short-Chain Ceramide Inhibits Agonist-Dependent Translocation of Neurotensin Receptor 1 to Structured Membrane Microdomains in Breast Cancer Cells
Supplementary Data from Targeting Melanoma with Dual Phosphoinositide 3-Kinase/Mammalian Target of Rapamycin Inhibitors
Authors: Marone Romina , Erhart Dominik , Mertz Ann C. , Bohnacker Thomas , Schnell Christian , Cmiljanovic Vladimir , Stauffer Frédéric , Garcia-Echeverria Carlos , Giese Bernd , Maira Sauveur-Michel , Wymann Matthias P.
Published: April 2023

Supplementary Data from Targeting Melanoma with Dual Phosphoinositide 3-Kinase/Mammalian Target of Rapamycin Inhibitors
Supplementary Table 1 from Thyroid Hormone Is a MAPK-Dependent Growth Factor for Human Myeloma Cells Acting via αvβ3 Integrin
Authors: Cohen Keren , Ellis Martin , Khoury Shafik , Davis Paul J. , Hercbergs Aleck , Ashur-Fabian Osnat
Published: April 2023

PDF file - 77K, Real-time PCR primers for apoptotic genes.
Supplementary Data from RanBPM Has Proapoptotic Activities That Regulate Cell Death Pathways in Response to DNA Damage
Authors: Atabakhsh Elnaz , Bryce Dawn M. , Lefebvre Karen J. , Schild-Poulter Caroline
Published: April 2023

Supplementary Data from RanBPM Has Proapoptotic Activities That Regulate Cell Death Pathways in Response to DNA Damage
Supplementary Data from FOXM1 Confers Acquired Cisplatin Resistance in Breast Cancer Cells
Authors: Kwok Jimmy M.-M. , Peck Barrie , Monteiro Lara J. , Schwenen Helma D.C. , Millour Julie , Coombes R. Charles , Myatt Stephen S. , Lam Eric W.-F.
Published: April 2023

Supplementary Data from FOXM1 Confers Acquired Cisplatin Resistance in Breast Cancer Cells
Supplementary Data from αB-Crystallin, an Effector of Unfolded Protein Response, Confers Anti-VEGF Resistance to Breast Cancer via Maintenance of Intracrine VEGF in Endothelial Cells
Authors: Ruan Qing , Han Song , Jiang Wen G. , Boulton Michael E. , Chen Zhi J. , Law Brian K. , Cai Jun
Published: April 2023

Supplementary Data from αB-Crystallin, an Effector of Unfolded Protein Response, Confers Anti-VEGF Resistance to Breast Cancer via Maintenance of Intracrine VEGF in Endothelial Cells
Supplementary Figure Legends 1-6, Methods from Regulation of Cell Cycle Genes and Induction of Senescence by Overexpression of OTX2 in Medulloblastoma Cell Lines
Authors: Bunt Jens , de Haas Talitha G. , Hasselt Nancy E. , Zwijnenburg Danny A. , Koster Jan , Versteeg Rogier , Kool Marcel
Published: April 2023

PDF file - 69K
Supplementary Figure 6 from Regulation of Cell Cycle Genes and Induction of Senescence by Overexpression of OTX2 in Medulloblastoma Cell Lines
Authors: Bunt Jens , de Haas Talitha G. , Hasselt Nancy E. , Zwijnenburg Danny A. , Koster Jan , Versteeg Rogier , Kool Marcel
Published: April 2023

PDF file - 672K
Supplementary Data from MDM2 Controls the Timely Expression of Cyclin A to Regulate the Cell Cycle
Authors: Frum Rebecca , Ramamoorthy Mahesh , Mohanraj Lathika , Deb Sumitra , Deb Swati Palit
Published: April 2023

Supplementary Data from MDM2 Controls the Timely Expression of Cyclin A to Regulate the Cell Cycle
Supplementary Figure 5 from Regulation of Cell Cycle Genes and Induction of Senescence by Overexpression of OTX2 in Medulloblastoma Cell Lines
Authors: Bunt Jens , de Haas Talitha G. , Hasselt Nancy E. , Zwijnenburg Danny A. , Koster Jan , Versteeg Rogier , Kool Marcel
Published: April 2023

PDF file - 942K
Supplementary Figure 4 from Regulation of Cell Cycle Genes and Induction of Senescence by Overexpression of OTX2 in Medulloblastoma Cell Lines
Authors: Bunt Jens , de Haas Talitha G. , Hasselt Nancy E. , Zwijnenburg Danny A. , Koster Jan , Versteeg Rogier , Kool Marcel
Published: April 2023

PDF file - 1.4MB
Supplementary Figure 3 from Regulation of Cell Cycle Genes and Induction of Senescence by Overexpression of OTX2 in Medulloblastoma Cell Lines
Authors: Bunt Jens , de Haas Talitha G. , Hasselt Nancy E. , Zwijnenburg Danny A. , Koster Jan , Versteeg Rogier , Kool Marcel
Published: April 2023

PDF file - 807K
Supplementary Figure 2 from Regulation of Cell Cycle Genes and Induction of Senescence by Overexpression of OTX2 in Medulloblastoma Cell Lines
Authors: Bunt Jens , de Haas Talitha G. , Hasselt Nancy E. , Zwijnenburg Danny A. , Koster Jan , Versteeg Rogier , Kool Marcel
Published: April 2023

PDF file - 610K
Supplementary Figure Legend 1 from Oxidative Stress and Prostate Cancer Progression Are Elicited by Membrane-Type 1 Matrix Metalloproteinase
Authors: Nguyen Hoang-Lan , Zucker Stanley , Zarrabi Kevin , Kadam Pournima , Schmidt Cathleen , Cao Jian
Published: April 2023

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Supplementary Figure 1 from Oxidative Stress and Prostate Cancer Progression Are Elicited by Membrane-Type 1 Matrix Metalloproteinase
Authors: Nguyen Hoang-Lan , Zucker Stanley , Zarrabi Kevin , Kadam Pournima , Schmidt Cathleen , Cao Jian
Published: April 2023

PDF File - (92K) -LNCaP/GFP and LNCaP/MT1-MMP-GFP cells were trypsinized and resuspended in the presence of 1�M H2-PFTMRos for 15 minutes at 37{degree sign}C. Cells were centrifuged, washed in PBS, and resuspended in phenol red-free RPMI, added to tissue culture plates, and imaged immediately. Images were taken again at 2 hours and 24 hours after seeding. Left. Mean fluorescence intensity of cells from 5 different image fields were automatically calculated for each group using NIS Elements BR 3.0 imaging software and shown graphically. *P<0.05 between respective LNCaP/GFP and LNCaP/MT1-MMP-GFP samples for each respective time points. # P<0.05 between LNCaP/MT1-MMP-GFP samples .
Supplementary Data from PALB2 Functionally Connects the Breast Cancer Susceptibility Proteins BRCA1 and BRCA2
Authors: Zhang Fan , Fan Qiang , Ren Keqin , Andreassen Paul R.
Published: April 2023

Supplementary Data from PALB2 Functionally Connects the Breast Cancer Susceptibility Proteins BRCA1 and BRCA2
Supplementary Data from Atypical Protein Kinase C ζ Exhibits a Proapoptotic Function in Ovarian Cancer
Authors: Nazarenko Irina , Jenny Marcel , Keil Jana , Gieseler Cornelia , Weisshaupt Karen , Sehouli Jalid , Legewie Stefan , Herbst Lena , Weichert Wilko , Darb-Esfahani Silvia , Dietel Manfred , Schäfer Reinhold , Ueberall Florian , Sers Christine
Published: April 2023

Supplementary Data from Atypical Protein Kinase C ζ Exhibits a Proapoptotic Function in Ovarian Cancer
Supplementary Data from z-Leucinyl-Leucinyl-Norleucinal Induces Apoptosis of Human Glioblastoma Tumor–Initiating Cells by Proteasome Inhibition and Mitotic Arrest Response
Authors: Monticone Massimiliano , Biollo Emanuela , Fabiano Andrea , Fabbi Marina , Daga Antonio , Romeo Francesco , Maffei Massimo , Melotti Alice , Giaretti Walter , Corte Giorgio , Castagnola Patrizio
Published: April 2023

Supplementary Figures S1-S6 and Supplementary Tables S1-S3.
Supplementary Figure 1 from SDF-1α Induces PDGF-B Expression and the Differentiation of Bone Marrow Cells into Pericytes
Authors: Hamdan Randala , Zhou Zhichao , Kleinerman Eugenie S.
Published: April 2023

PDF file - 31K
Supplementary Data from Hepatocyte Nuclear Factor-4–Independent Synthesis of Coagulation Factor VII in Breast Cancer Cells and Its Inhibition by Targeting Selective Histone Acetyltransferases
Authors: Koizume Shiro , Yokota Naho , Miyagi Etsuko , Hirahara Fumiki , Nakamura Yoshiyasu , Sakuma Yuji , Yoshida Akira , Kameda Yoichi , Tsuchiya Eiju , Ruf Wolfram , Miyagi Yohei
Published: April 2023

Supplementary Data from Hepatocyte Nuclear Factor-4–Independent Synthesis of Coagulation Factor VII in Breast Cancer Cells and Its Inhibition by Targeting Selective Histone Acetyltransferases
Supplementary Data from Requirement of Phosphatidylinositol(3,4,5)Trisphosphate in Phosphatidylinositol 3-Kinase-Induced Oncogenic Transformation
Authors: Denley Adam , Gymnopoulos Marco , Kang Sohye , Mitchell Christina , Vogt Peter K.
Published: April 2023

Supplementary Data from Requirement of Phosphatidylinositol(3,4,5)Trisphosphate in Phosphatidylinositol 3-Kinase-Induced Oncogenic Transformation
Supplementary Data from Elevated Poly-(ADP-Ribose)-Polymerase Activity Sensitizes Retinoblastoma-Deficient Cells to DNA Damage–Induced Necrosis
Authors: Liu Huiping , Knabb James R. , Spike Benjamin T. , Macleod Kay F.
Published: April 2023

Supplementary Data from Elevated Poly-(ADP-Ribose)-Polymerase Activity Sensitizes Retinoblastoma-Deficient Cells to DNA Damage–Induced Necrosis
Supplementary Figure 1 from Cytokine Induction of Tumor Necrosis Factor Receptor 2 Is Mediated by STAT3 in Colon Cancer Cells
Authors: Hamilton Kathryn E. , Simmons James G. , Ding Shengli , Van Landeghem Laurianne , Lund P. Kay
Published: April 2023

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Supplementary Table 2 from Role of CXCL13-CXCR5 Crosstalk Between Malignant Neuroblastoma Cells and Schwannian Stromal Cells in Neuroblastic Tumors
Authors: Del Grosso Federica , Coco Simona , Scaruffi Paola , Stigliani Sara , Valdora Francesca , Benelli Roberto , Salvi Sandra , Boccardo Simona , Truini Mauro , Croce Michela , Ferrini Silvano , Longo Luca , Tonini Gian Paolo
Published: April 2023

Supplementary Table 2 from Role of CXCL13-CXCR5 Crosstalk Between Malignant Neuroblastoma Cells and Schwannian Stromal Cells in Neuroblastic Tumors
Supplementary Figure Legends 1-8 from Inhibition of DNA-Dependent Protein Kinase Induces Accelerated Senescence in Irradiated Human Cancer Cells
Authors: Azad Arun , Jackson Susan , Cullinane Carleen , Natoli Anthony , Neilsen Paul M. , Callen David F. , Maira Sauveur-Michel , Hackl Wolfgang , McArthur Grant A. , Solomon Benjamin
Published: April 2023

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Supplementary Data from Targeted Knockdown of SEPT9_v1 Inhibits Tumor Growth and Angiogenesis of Human Prostate Cancer Cells Concomitant with Disruption of Hypoxia-Inducible Factor-1 Pathway
Authors: Amir Sharon , Golan Maya , Mabjeesh Nicola J.
Published: April 2023

Supplementary Data from Targeted Knockdown of SEPT9_v1 Inhibits Tumor Growth and Angiogenesis of Human Prostate Cancer Cells Concomitant with Disruption of Hypoxia-Inducible Factor-1 Pathway
Supplementary Tables 1-2 from miR-200 Inhibits Lung Adenocarcinoma Cell Invasion and Metastasis by Targeting Flt1/VEGFR1
Authors: Roybal Jonathon D. , Zang Yi , Ahn Young-Ho , Yang Yanan , Gibbons Don L. , Baird Brandi N. , Alvarez Cristina , Thilaganathan Nishan , Liu Diane D. , Saintigny Pierre , Heymach John V. , Creighton Chad J. , Kurie Jonathan M.
Published: April 2023

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Supplementary Figure 6 from Inhibition of DNA-Dependent Protein Kinase Induces Accelerated Senescence in Irradiated Human Cancer Cells
Authors: Azad Arun , Jackson Susan , Cullinane Carleen , Natoli Anthony , Neilsen Paul M. , Callen David F. , Maira Sauveur-Michel , Hackl Wolfgang , McArthur Grant A. , Solomon Benjamin
Published: April 2023

PDF file - 4.6MB, Representative immunofluorescence images of phospho-ATM (Ser1981) foci in H460 and A549 cells at 30 minutes after 10 Gy dose of radiation (x 60 magnification). Green, phospho-ATM foci. Blue, DAPI staining.
Supplementary Figure 5 from Inhibition of DNA-Dependent Protein Kinase Induces Accelerated Senescence in Irradiated Human Cancer Cells
Authors: Azad Arun , Jackson Susan , Cullinane Carleen , Natoli Anthony , Neilsen Paul M. , Callen David F. , Maira Sauveur-Michel , Hackl Wolfgang , McArthur Grant A. , Solomon Benjamin
Published: April 2023

PDF file - 9MB, Representative immunofluorescence images of gamma H2AX (Ser139) foci in H460 and A549 cells at indicated time points after 4 Gy radiation (x 60 magnification). Green, �H2AX foci. Blue, DAPI staining. Below, Number of gamma H2AX foci per cell. Data are mean +/- SEM from three independent experiments. ***, P<0.001 **, P<0.01 *, P<0.05.
Supplementary Figure 1 from MicroRNA-30c-2* Expressed in Ovarian Cancer Cells Suppresses Growth Factor–Induced Cellular Proliferation and Downregulates the Oncogene BCL9
Authors: Jia Wei , Eneh Juliet O. , Ratnaparkhe Supriya , Altman Molly K. , Murph Mandi M.
Published: April 2023

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Supplementary Fig 5 from Heme Sequestration Effectively Suppresses the Development and Progression of Both Lung Adenocarcinoma and Squamous Cell Carcinoma
Authors: Dey Sanchareeka , Ashrafi Adnin , Vidal Chantal , Jain Nivesh , Kalainayakan Sarada Preeta , Ghosh Poorva , Alemi Parinaz Sadat , Salamat Narges , Konduri Purna Chaitanya , Kim Jung-whan , Zhang Li
Published: April 2023

Supplementary Figure 5. The effect of HeSP2 treatment on the levels of hypoxia markers and CASP3. A, Representative IHC images of lung tissue sections from KLLuc mice showing the levels of HIF1A. B, Representative IHC images of lung tissue sections from KLLuc mice showing the levels of CA9. C, Representative IHC images of lung tissue sections from KLLuc mice showing the levels of CASP3. Shown are montage and 10X images of lung tissue sections stained with DAPI (row 1) and antibodies against the indicated protein (row 2). The light green lines in DAPI montages outline the tumors in the lung. The white rectangles denote the regions shown in 10X images. Scale bar, montage, 1mm; 10X, 100Âµm. D, Graph showing quantified levels of HIF1A correlating with A. E, Graph showing quantified levels of CA9 correlating with B. F, Graph showing quantified levels of CASP3 correlating with C. For statistical analysis, the levels in HeSP2-treated tumors were compared with the levels in control tumors with a Welch two-sample t test. **, P < 0.005.
Supplementary Table 1, Supplemental Figures 1-5 from Protein Kinase D–Dependent Downregulation of Immediate Early Genes through Class IIA Histone Deacetylases in Acute Lymphoblastic Leukemia
Authors: Sun Guangyan , Shvab Anna , Leclerc Guy J. , Li Bin , Beckedorff Felipe , Shiekhattar Ramin , Barredo Julio C.
Published: April 2023

Supplementary Table 1. Antibodies used in the study Figure S1. AICAR-induced downregulation of IEGs mRNA expression in ALL cells. Figure S2. The mechanism of AICAR-induced IEGs downregulation is AMPK-independent. Figure S3. The PKC inhibitor GF109203X suppresses IEGs expression in ALL cells. Figure S4. PKD inhibition downregulates IEGs transcription in ALL cells. Figure S5. The PKD inhibitor CRT synergizes with regorafenib and dexamethasone in ALL cells.
Supplementary Table 1 from Tumor-Resident Stromal Cells Promote Breast Cancer Invasion through Regulation of the Basal Phenotype
Authors: Hanley Christopher J. , Henriet Elodie , Sirka Orit Katarina , Thomas Gareth J. , Ewald Andrew J.
Published: April 2023

Breast cancer subtype specific WGCN analysis.
Figure S2 from Membrane-Associated RING-CH 8 Functions as a Novel PD-L1 E3 Ligase to Mediate PD-L1 Degradation Induced by EGFR Inhibitors
Authors: Qian Guoqing , Guo Jianping , Vallega Karin A. , Hu Changjiang , Chen Zhen , Deng Yunfu , Wang Qiming , Fan Songqing , Ramalingam Suresh S. , Owonikoko Taofeek K. , Wei Wenyi , Sun Shi-Yong
Published: April 2023

Osimertinib decreases PD-L1 mRNA levels (A-C) and exerts differential effects on reducing PD-L1 induced by EGF and INFg (D and E), which might increase PD-L1 via different mechanisms (F), in EGFRm NSCLC cells.
Supplementary Data from Destrin Contributes to Lung Adenocarcinoma Progression by Activating Wnt/β-Catenin Signaling Pathway
Authors: Zhang Hui-Juan , Chang Wen-Jing , Jia Cai-Yun , Qiao Ling , Zhou Jing , Chen Qing , Zheng Xiao-Wei , Zhang Jian-Hua , Li Hong-Chao , Yang Zheng-Yan , Liu Zhong-Hua , Liu Guang-Chao , Ji Shao-Ping , Lu Feng
Published: April 2023

Supplementary Materials and Methods
Supplementary Materials and Methods from Mutant p53 Attenuates Oxidative Phosphorylation and Facilitates Cancer Stemness through Downregulating miR-200c–PCK2 Axis in Basal-Like Breast Cancer
Authors: Chao Chi-Hong , Wang Chen-Yun , Wang Cing-Hong , Chen Ting-Wen , Hsu Huai-Yu , Huang Hao-Wei , Li Chia-Wei , Mai Ru-Tsun
Published: April 2023

Supplementary Materials and Methods
Figure S3 from Comprehensive Mutational Analysis of the BRCA1-Associated DNA Helicase and Tumor-Suppressor FANCJ/BACH1/BRIP1
Authors: Calvo Jennifer A. , Fritchman Briana , Hernandez Desiree , Persky Nicole S. , Johannessen Cory M. , Piccioni Federica , Kelch Brian A. , Cantor Sharon B.
Published: April 2023

Controls of mutation screen
Figure S2 from Comprehensive Mutational Analysis of the BRCA1-Associated DNA Helicase and Tumor-Suppressor FANCJ/BACH1/BRIP1
Authors: Calvo Jennifer A. , Fritchman Briana , Hernandez Desiree , Persky Nicole S. , Johannessen Cory M. , Piccioni Federica , Kelch Brian A. , Cantor Sharon B.
Published: April 2023

Predicted functional consequence of FANCJ mutations using in silico programs
Figure S1 from Comprehensive Mutational Analysis of the BRCA1-Associated DNA Helicase and Tumor-Suppressor FANCJ/BACH1/BRIP1
Authors: Calvo Jennifer A. , Fritchman Briana , Hernandez Desiree , Persky Nicole S. , Johannessen Cory M. , Piccioni Federica , Kelch Brian A. , Cantor Sharon B.
Published: April 2023

Validation of mutation screen
Table S3 from A Novel miR-146a-POU3F2/SMARCA5 Pathway Regulates Stemness and Therapeutic Response in Glioblastoma
Authors: Cui Tiantian , Bell Erica H. , McElroy Joseph , Liu Kevin , Sebastian Ebin , Johnson Benjamin , Gulati Pooja Manchanda , Becker Aline Paixao , Gray Ashley , Geurts Marjolein , Subedi Depika , Yang Linlin , Fleming Jessica L. , Meng Wei , Barnholtz-Sloan Jill S. , Venere Monica , Wang Qi-En , Robe Pierre A. , Haque S. Jaharul , Chakravarti Arnab
Published: April 2023

Table S3. Univariable and Multivariable analyses of clinic-pathologic parameters of overall survival in patient with GBM
Supplementary Materials from A Novel miR-146a-POU3F2/SMARCA5 Pathway Regulates Stemness and Therapeutic Response in Glioblastoma
Authors: Cui Tiantian , Bell Erica H. , McElroy Joseph , Liu Kevin , Sebastian Ebin , Johnson Benjamin , Gulati Pooja Manchanda , Becker Aline Paixao , Gray Ashley , Geurts Marjolein , Subedi Depika , Yang Linlin , Fleming Jessica L. , Meng Wei , Barnholtz-Sloan Jill S. , Venere Monica , Wang Qi-En , Robe Pierre A. , Haque S. Jaharul , Chakravarti Arnab
Published: April 2023

Supplementary Materials
Figure S8 from A Novel miR-146a-POU3F2/SMARCA5 Pathway Regulates Stemness and Therapeutic Response in Glioblastoma
Authors: Cui Tiantian , Bell Erica H. , McElroy Joseph , Liu Kevin , Sebastian Ebin , Johnson Benjamin , Gulati Pooja Manchanda , Becker Aline Paixao , Gray Ashley , Geurts Marjolein , Subedi Depika , Yang Linlin , Fleming Jessica L. , Meng Wei , Barnholtz-Sloan Jill S. , Venere Monica , Wang Qi-En , Robe Pierre A. , Haque S. Jaharul , Chakravarti Arnab
Published: April 2023

Fig. S8 Expression of cancer stem cell markers after overexpression of miR-146a in GBM cells
Table S1 from IQGAP3, a YAP Target, Is Required for Proper Cell-Cycle Progression and Genome Stability
Authors: Leone Marina , Cazorla-Vázquez Salvador , Ferrazzi Fulvia , Wiederstein Janica L. , Gründl Marco , Weinstock Grit , Vergarajauregui Silvia , Eckstein Markus , Krüger Marcus , Gaubatz Stefan , Engel Felix B.
Published: April 2023

siRNA sequence information
Movie 2 from IQGAP3, a YAP Target, Is Required for Proper Cell-Cycle Progression and Genome Stability
Authors: Leone Marina , Cazorla-Vázquez Salvador , Ferrazzi Fulvia , Wiederstein Janica L. , Gründl Marco , Weinstock Grit , Vergarajauregui Silvia , Eckstein Markus , Krüger Marcus , Gaubatz Stefan , Engel Felix B.
Published: April 2023

HeLa cell stably transfected with mCherry-α-tubulin transfected with siIQ3#1.
Movie 1 from IQGAP3, a YAP Target, Is Required for Proper Cell-Cycle Progression and Genome Stability
Authors: Leone Marina , Cazorla-Vázquez Salvador , Ferrazzi Fulvia , Wiederstein Janica L. , Gründl Marco , Weinstock Grit , Vergarajauregui Silvia , Eckstein Markus , Krüger Marcus , Gaubatz Stefan , Engel Felix B.
Published: April 2023

HeLa cell stably transfected with mCherry-α-tubulin transfected with siCtrl.
Figure S2 from A Novel miR-146a-POU3F2/SMARCA5 Pathway Regulates Stemness and Therapeutic Response in Glioblastoma
Authors: Cui Tiantian , Bell Erica H. , McElroy Joseph , Liu Kevin , Sebastian Ebin , Johnson Benjamin , Gulati Pooja Manchanda , Becker Aline Paixao , Gray Ashley , Geurts Marjolein , Subedi Depika , Yang Linlin , Fleming Jessica L. , Meng Wei , Barnholtz-Sloan Jill S. , Venere Monica , Wang Qi-En , Robe Pierre A. , Haque S. Jaharul , Chakravarti Arnab
Published: April 2023

Fig. S2 Effect of miR-146a on cell invasion in U87MG/EGFRvIII, GBM30, 08-387, and LN229 cells
Table S4-6 from An IFNγ/STAT1/JMJD3 Axis Induces ZEB1 Expression and Promotes Aggressiveness in Lung Adenocarcinoma
Authors: Yang Jianjian , Wang Xue , Huang Bing , Liu Rong , Xiong Hui , Ye Fan , Zeng Chenxi , Fu Xiangning , Li Lequn
Published: April 2023

Table S4. EMT-core gene signatures consisting of 130 genes. Table S5. Total 58 genes differentially expressed in A549 cells after 24 h of stimulation with IFN-g. Table S6. Total 58 genes differentially expressed in HCC827 cells after 24 h of stimulation with IFN-g.
Figure S14 from A Novel miR-146a-POU3F2/SMARCA5 Pathway Regulates Stemness and Therapeutic Response in Glioblastoma
Authors: Cui Tiantian , Bell Erica H. , McElroy Joseph , Liu Kevin , Sebastian Ebin , Johnson Benjamin , Gulati Pooja Manchanda , Becker Aline Paixao , Gray Ashley , Geurts Marjolein , Subedi Depika , Yang Linlin , Fleming Jessica L. , Meng Wei , Barnholtz-Sloan Jill S. , Venere Monica , Wang Qi-En , Robe Pierre A. , Haque S. Jaharul , Chakravarti Arnab
Published: April 2023

Fig. S14 Correlation between POU3F2 and SMARCA5 at mRNA level in TCGA datasets
Figure S13 from A Novel miR-146a-POU3F2/SMARCA5 Pathway Regulates Stemness and Therapeutic Response in Glioblastoma
Authors: Cui Tiantian , Bell Erica H. , McElroy Joseph , Liu Kevin , Sebastian Ebin , Johnson Benjamin , Gulati Pooja Manchanda , Becker Aline Paixao , Gray Ashley , Geurts Marjolein , Subedi Depika , Yang Linlin , Fleming Jessica L. , Meng Wei , Barnholtz-Sloan Jill S. , Venere Monica , Wang Qi-En , Robe Pierre A. , Haque S. Jaharul , Chakravarti Arnab
Published: April 2023

Fig. S13 Tumor suppression by miR-146a is rescued by POU3F2
Figure S12 from A Novel miR-146a-POU3F2/SMARCA5 Pathway Regulates Stemness and Therapeutic Response in Glioblastoma
Authors: Cui Tiantian , Bell Erica H. , McElroy Joseph , Liu Kevin , Sebastian Ebin , Johnson Benjamin , Gulati Pooja Manchanda , Becker Aline Paixao , Gray Ashley , Geurts Marjolein , Subedi Depika , Yang Linlin , Fleming Jessica L. , Meng Wei , Barnholtz-Sloan Jill S. , Venere Monica , Wang Qi-En , Robe Pierre A. , Haque S. Jaharul , Chakravarti Arnab
Published: April 2023

Fig. S12 Expression of TRAF6 in miR-146a overexpression models
Figure S1 from A Novel miR-146a-POU3F2/SMARCA5 Pathway Regulates Stemness and Therapeutic Response in Glioblastoma
Authors: Cui Tiantian , Bell Erica H. , McElroy Joseph , Liu Kevin , Sebastian Ebin , Johnson Benjamin , Gulati Pooja Manchanda , Becker Aline Paixao , Gray Ashley , Geurts Marjolein , Subedi Depika , Yang Linlin , Fleming Jessica L. , Meng Wei , Barnholtz-Sloan Jill S. , Venere Monica , Wang Qi-En , Robe Pierre A. , Haque S. Jaharul , Chakravarti Arnab
Published: April 2023

Fig. S1 miR-146a inhibits cell proliferation of PDX lines GBM12 and GBM43