bluuebunny/crossref_metadata_2025 huggingface dataset:
Induction of Antioxidant Enzyme Activity by Sandy Everlasting (Helichrysum arenarium) in Galleria mellonella
Authors: - Serhat KAYA
Published: December 2024

Helichrysum arenarium (L.), which spreads in a wide geography between European and Asia, is a medicinal plant mostly used in detoxification and digestive system diseases in that region. The greater wax moth Galleria mellonella is preferred as an invertebrate model organism in many studies to understand the effects of many disease factors, including human pathogens, treatments developed against them, and innate immunity. The aim of this study is to determine the effects of H. arenarium extracts, which were previously determined to be effective on G. mellonella cell-mediated immune responses, on G. mellonella hemolymph antioxidant enzymes. For this purpose, catalase, superoxide dismutase, glutathione-s-transferase activities and malondialdehyde levels in hemolymph collected after injection of H. arenarium extracts into G. mellonella hemocoel were determined. As a result of the study, it was determined that a 0.5% dose increased catalase, superoxide dismutase and glutathione-s-transferase activities compared to the control. The determined dose had no effect on malondialdehyde formation. The findings showed that H. arenarium extracts had a positive effect on G. mellonella hemolymph antioxidant enzymes at a dose of a 0.5%, and that the same dose supported cell-mediated immunity in the previous study. Accordingly, it was concluded that 0.5% dose of H. arenarium extracts had a immunomodulatory effects on immunity.
A Comprehensive Approach to Summarization: The Role of Retrieval-Augmented Generation
Authors: - Vanita Mhaske , - Rhishikesh KAdam
Published: December 2024

There are many types of summaries that can be created, depending on the nature of the input documents—whether they are related to law, medicine, or other fields. It is important to understand the subject matter first, as different documents require different handling approaches. Highlighting key points is crucial for focusing on specific sentences. Depending on the topic and the desired output, various summarization models can be used. In this context, we particularly focus on the RAG system and how it can be beneficial for achieving better results.
A Systematic Literature Review on Factors Affecting Financial Risk Tolerance
Authors: - Chintu H Thakkar , - Dr Vatsalbhai B Patel
Published: December 2024

Financial risk tolerance is a crucial determinant of investment behaviour, yet its underlying factors remain multifaceted and complex. This review paper investigates the interplay between biopsychosocial factors and financial risk tolerance, aiming to clarify the relationship shaping individuals' propensity for risk in financial decision-making.
Biological factors, encompassing genetic predispositions and neurological processes, influence risk perception and decision-making. Recent advancements in neuroscience have highlighted the role of brain structures such as the amygdala and prefrontal cortex in assessing risk, shedding light on how individual differences in neural functioning contribute to diverse risk-taking behaviors.
Advance in Riboflavin Biosynthesis: Fermentation Techniques, Enzymatic Pathways, Utilisation and Industrial Applications
Authors: - Vivek J. Jetani
Published: December 2024

Two molecules of ribulose 5-phosphate and one molecule of GTP are needed as substrates for the production of one riboflavin molecule. GTP's imidazole ring is hydrolytically opened to produce a 4,5-diaminopyrimidine, which is then followed by deamination, side chain reduction, and dephosphorylation to produce 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione. 6,7-dimethyl-8-ribityllumazine is produced by condensing 5-amino-6-ribitylamino2,4(1H,3H)-pyrimidinedione with 3,4-dihydroxy-2-butanone 4-phosphate, which is derived from ribulose 5-phosphate. Riboflavin and 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione are produced upon dismutation of the lumazine derivative and are then recycled throughout the biosynthetic process. Many studies have been conducted on the structure of the biosynthetic enzyme 6,7-dimethyl-8-ribityllumazine synthase. Under the direction of the inducible Pxyl promoter in B. subtilis PY, overexpression of glucose-6-phosphate dehydrogenase (G6PDH) altered carbon flow in Bacillus subtilis through the pentose phosphate (PP) pathway. The yield of riboflavin and the availability of ribulose-5-phosphate (Ru5P) will change if the carbon input into the PP pathway is altered. The specific growth rate remained constant, but the glucose consumption rate significantly increased as a result of overexpres¬sion of G6PDH. A 25%±2 increase in riboflavin synthesis was achieved. Lower acid production (acetate andpyruvate) and higher acetoin formation were noted in comparison to by-product formation in flask culture. The results of metabolic studies and carbon flux redistribution showed that overexpression of G6PDH increases the fluxes in the PP pathway.
A Comparative Study of Marketing Strategies in the Digital Age for MSMEs in Zambia
Authors: - Sidney Kawimbe , - Precious Sihweya
Published: December 2024

Micro, Small, and Medium Enterprises (MSMEs) are critical drivers of economic growth and development in Zambia and contribute significantly to the Gross Domestic Product (GDP), and indeed, act as fundamental sources of entrepreneurship, creation of jobs, and driving poverty reduction. However, these are enterprises that are playing in the evolving digital landscape and hence will have to contend with both challenges and opportunities. What worked for locally marketing your product via conventional means just doesn’t work as effectively in a globally digital economy. Social media platforms, e-commerce websites, and search engine optimization (SEO) are digital marketing tools that allow MSMEs to achieve good reach and engagement with customers in both local and international markets. Even though digital marketing has huge potential benefits, many Zambian MSMEs face hurdles in adopting it. There are many deterrent factors in the development of digital marketing in Zambia such as poor infrastructure, high cost of internet access, lack of digital experience, and budget limitations. These are all vital barriers further increasing the gap between urban and rural settings. Success stories show an increasingly important role of digital tools in shaping success stories of MSMEs that are not afraid to change, such as increased revenue, innovation, and resilience. This study investigates the efficacy of traditional and digital marketing channels of MSMEs in Zambia concerning the variables that affect marketing decisions and the role of digital tools in the performance of business. Through case studies and identifying best practices, this analysis delivers actions that MSMEs are undertaking in the digital transition. For many MSMEs, the study emphasizes the importance of strategic marketing and highlights that a hybrid approach (a combination of digital and traditional approaches) is most appropriate. Government policies, private sector efforts, and non-governmental organizations (NGOs) were highlighted as vital drivers of digital transformation. Infrastructural, financial, and educational barriers are addressed so that stakeholders in Zambian MSMEs can harness digital tools to enable sustainable growth and competitive resilience in a dynamic business environment.
Data Lake Design Patterns: Building Scalable Architectures for Enterprise Analytics
Authors: - Venkata Raghavendra Vutti
Published: December 2024

As enterprises battle exponential data expansion and increasingly complicated analytics requirements, the
demand for scalable, efficient data infrastructures has never been more vital. This extensive technical
article gives a complete approach to developing and implementing a modern data lake architecture using
AWS cloud services. A production-grade solution leverages Amazon S3 for persistent storage, AWS Glue
for robust ETL processing, and Amazon Athena for cost-effective querying capabilities. The design
integrates fundamental features of data governance, security, and operational excellence while solving
typical difficulties in enterprise data management. A deep investigation of component layers-from data
ingestion to storage organization, processing pipelines, and query optimization provides practical insights
for developing a scalable data platform. The article covers essential concerns for data architects and
engineers, including storage optimization tactics, data quality frameworks, monitoring systems, and cost
control procedures. Real-world implementation patterns and case studies highlight how firms can migrate
from classic data warehousing systems to modern, cloud-native data architectures that enable advanced
analytics and machine learning projects.
संस्कृत साहित्य में भाग्य एवं कर्म का समन्वयात्मक विश्लेषण :
Authors: - डॉ. वन्दना मिश्रा
Published: December 2024

भाग्य एवं पुरूषार्थ दोनों का ही अपना-अपना महत्व है, लेकिन इतिहास पर दृष्टि डाली जाए तो सामने आएगा कि जीवन में पुरूषार्थ की भूमिका भाग्य से कहीं अधिक महत्वपूर्ण है। भाग्य की कुंजी सदैव हमारे कर्म के हाथ में होती है, अर्थात कर्म करेंगे तो ही भाग्योदय होगा। जब कि पुरूषार्थ इस विषय में पूर्णतः स्वतंत्र है। माना कि पुरूषार्थ सर्वोपरी है किन्तु इतना कहने मात्र से भाग्य की महता तो कम नहीं हो जाती । इन्सान द्वारा किए गए कर्मों से ही उसके भाग्य का निर्माण होता है । लेकिन कौन सा कर्म, कैसा कर्म और किस दिशा में कर्म करने से मनुष्य अपने भाग्य का सही निर्माण कर सकता है-ये जानने का जो माध्यम है, उसी का नाम ज्योतिष एवं हस्तरेखा है। स्ांसार में कुछ लोग पुरुषार्थ को ही विशेष महत्त्व देते है उनके लिए भाग्य से भी अधिक महत्त्वपूर्ण पुरुषार्थ है। वे कहते हैं अगर भाग्य से आपको कुछ भी नहीं मिलता तो आप पुरुषार्थ के द्वारा उसको अवश्य प्राप्त कर सकते हैं। अतः अनेक विचारकों के अनुसार परिश्रम पर भरोसा करने वाले उद्यमियों को ही धन-सम्पत्ति, सफलता प्राप्त होती है। भाग्य ही सब कुछ है वह तो कामचोरों का ही कथन है।
Morphological growth of Sri Vijaya Puram (Port Blair) town in Andaman and Nicobar Islands
Authors: - Kailash Chandra Joshi
Published: December 2024

The contemporary world is an urban world. This is apparent in the expansion of city and urban area and the extension of its influences across much of the habitable surface of the earth. A city is a man-made habitat consisting of various functions. These functions occupy the vast area of the city used for these activities. This structural form is defined as morphology. The morphology of a city undergoes transformation over time due to a variety of reasons.
Food Waste Management: A Way Forward for Ensuring Food Security and Sustainability
Authors: Sarthi  , Singh Manisha , Wagh Arti , Johar Vishal , Bisht Vinita
Published: December 2024

The current era is marked by a significant challenge in food waste, an issue that has gained prominence in recent years. Traditional approaches to tackle this problem involve three essential steps: reduce, reuse, and recycle. Successfully minimizing waste at various stages of the food chain, including post-harvest, supply, processing, and consumer levels, has shown remarkable results, contributing positively to overall food security and environmental sustainability. Efforts have been made to explore the potential of nanotechnology in enhancing food security in India. Key factors such as agricultural efficiency, soil health, water conservation, and food safety during storage and distribution can be significantly influenced by advancements in nanotechnology. The framework comprises two phases: firstly, aligning nanotechnology with thematic areas across the agricultural value chain, and secondly, linking nanotechnology applications within these thematic areas to the essential determinants of food security.
Rapid and efficient isolation of genomic DNA from Okra (Abelmoschus esculentus L.): A streamlined alternative to conventional methods
Authors: Sarthi  , Johar Vishal , Singh Narayan , Alaklabi Abdullah , Khan Salim
Published: December 2024

Isolating high-quality genomic DNA from Abelmoschus esculentus (okra) is very hard because it contains a lot of acidic polysaccharides (mucilage) and polyphenols, which can make DNA extraction harder. This study selected twenty different genotypes of okra, carefully harvested healthy juvenile leaves, and washed them with distilled water to minimize contamination. A novel, cost-effective, rapid, and simplified method for DNA extraction was standardized, addressing the specific challenges posed by okra's biochemical composition in comparison to the conventional methods. The modified protocol yielded 20–30% more DNA compared to conventional methods, resulting in superior quality and purity.  The DNA isolated using this method was sufficiently pure for approximately 275-300 PCR reactions, enabling accurate downstream applications such as genetic diversity analysis. This optimized protocol represents a significant advancement in genomic DNA isolation from okra, providing a reliable and efficient alternative to conventional approaches.
Alteration in brain histology of fresh water fish Cirrhinus mrigala after acute exposure of aluminium chloride (AlCl3)
Authors: Rani Rekha , Pandey Sonal
Published: December 2024

Water is the lifeline of our planet, essential for all forms of life to thrive. Its presence sustains ecosystems, regulates climate, and is crucial for human health and agriculture. As a universal solvent, water plays a vital role in shaping landscapes and supporting biodiversity, making it indispensable for the health and sustainability of both life and Earth. The present study exposed the freshwater fish Cirrhinus mrigala to aluminum chloride to evaluate its toxicological effects. This study determined the lethal concentration (LC50) of aluminum chloride in the freshwater fish Cirrhinus mrigala to be 0.087 ml/L after 24, 48, 72, and 96 hours. In order to evaluate the toxicological effects of aluminum chloride on brain tissues of Cirrhinus mrigala, the sublethal concentration (1/10th of LC50),.e., 0.0087 ml/L, was given to the fishes for 7, 14, 21, and 28 days. After exposing the fish Cirrhinus mrigala to aluminum chloride for 7, 14, 21, and 28 days, we observed behavioral changes like erratic swimming, hyperventilation, and aggressiveness. In the present study, after the exposure of aluminum chloride sublethal concentration to Cirrhinus mrigala, observed histological alterations in the brain tissues revealed by the necrosis in nerve cells, edema, aggregation of glial cells, and structural degeneration during the acute study, when compared to the control group. The overall results emphasize the necessity of rigorous monitoring and regulation to mitigate the adverse effects of pollutants on freshwater ecosystems and their inhabitants. by prioritizing the preservation of water quality to safeguard the delicate balance of aquatic life within these vital habitats for the benefit of both current and future generations. More studies on the effects of such chemical substances are required to be done in the fields of aquatic toxicology.
A questionnaire-based study on industrial waste management in Indian biopharmaceutical industries
Authors: Pringle Ishika , Dadwal Navjeevan , Kumar Arun
Published: December 2024

This study investigates industrial waste management practices within the Indian biopharmaceutical sector through a questionnaire-based approach.
The questionnaire, distributed among ten Indian biopharmaceutical industries (Himachal Pradesh (30°57'26.3"N 76°47'27.4"E), Uttarakhand (30°19'03.8"N 78°01'55.4"E), East Sikkim (27°19'54.5"N 88°36'49.4"E), and Bangalore (12°58'19.4"N 77°36'53.3"E)), explored various aspects of industrial waste management, including disposal methods, utilization of third-party vendors, collaboration with waste management entities, and initiatives towards sustainable practices such as wastewater treatment and reuse. The results of this study revealed current industrial waste management practices adopted by Indian biopharmaceutical industries, highlighting trends, challenges, and opportunities for improvement. This study contributed to the knowledge of industrial waste management practices of the Indian biopharmaceutical sector, offering information for policymakers, industry officials, and environmental professionals seeking to enhance industrial waste management strategies and promote sustainable development in the Indian biopharmaceutical industry.
Perceived constraints faced by the large cardamom growers of East Sikkim district: A case study
Authors: Bhutia Tashi Topgay , Roy Deepa , Peddi Naga Harsha Vardhan , Adhikary Ankur
Published: December 2024

Large cardamom (Amomum subulatum) is an important, high-value cash crop and main livelihood support for people in Sikkim. Till 2003–2004, India was considered the largest producer of large cardamom in the world, and the state of Sikkim alone contributed up to 88% of India's total production.  However, since 2004, over 60% of the cardamom plantations in the Sikkim state have experienced minimal productivity, leading to a significant decrease in both area and productivity. Due to factors such as climate change, pests and diseases, market prices, and traditional farming practices in India, Nepal now holds the title of being the world's leading producer. Under such an arena, the present study was conducted with the objective to identify the constraints faced by the farmers in large cardamom cultivation. This study was conducted in Sikkim state, which was selected purposively. A total of 50 respondents were selected randomly, and data was collected with a structured interview schedule. The study revealed that the growers ranked various types of constraints with mean scores of 3.38, 3.48, 3.46, 4.00, 3.70, 3.84, 3.32, 3.54, 4.54, 4.00, and 3.38. Overall, the growers faced a mean score of 3.98 for all constraints. The adoption of micropropagation was one of the major areas where the growers were facing problems. The study highlights the need for awareness and technical guidance for large cardamom growers to improve quality, productivity, and livelihood. Implementing feasible, environmentally, economically, and socially acceptable technologies is crucial.
Antibacterial and anti-inflammatory potential of Azadirachta indica against dental bacteria
Authors: Ruchi  , Kumar Mukesh
Published: December 2024

The aim of the present study was to identify the phytochemical constituents Azadirachta indica (Neem) leaves and evaluate their antibacterial and anti-inflammatory activities. The antibacterial properties of Azadirachta indica leaf extract were assessed using solvents such as ethanol, ethyl acetate, methanol and distilled water. These extracts were tested against two bacterial strains: Staphylococcus aureus and Streptococcus mutans. The results indicated that the ethyl acetate extract exhibited the highest zone of inhibition against both bacterial strains. Specifically, the zone for S. aureus ranged from 15.66-20.30 mm, while for S. mutans, it ranged from 21.50-27.56 mm. These finding demonstrate that A. indica possesses significant antimicrobial activity against both bacterial strains, with the ethyl acetate extract showing the most Pronounced inhibitory effect. Given its superior antibacterial activity, the ethyl acetate extract was further selected for the evaluation of its anti-inflammatory properties. Additionally, the chemical constituents responsible for these bioactivities were found out by using Gas Chromatography-Mass Spectrometry (GC-MS).
Exploring trends of wastewater treatment by using nano-materials and their composites with bio-polymer
Authors: Rauthan Shivani , Singh Ajay
Published: December 2024

Industries have employed various wastewater treatment methods and techniques to reduce pollution load, including biological oxygen demand (BOD), chemical oxygen demand (COD), total suspended solids (TSS), total dissolved solids (TDS), color, and toxic metals. This review paper aims to highlight and analyze various water treatments with special focus on the use of nanomaterials and their composites with biopolymers. Many other techniques for wastewater treatment (WWT) have been developed using nanotechnology. These techniques are usually based on nanofiltration, disinfection, adsorption and biosorption, photocatalysis, and sensing technology. Techniques like fluorescence in situ hybridization (FISH) are used for clarification of composition, amount analysis, and dispensing of various bacterial groups in biofilms and granules. By review, it can be concluded that when the old primary water treatment technique is clubbed with nano-composite adsorption, composites containing specific biopolymers such as starch, chitosan, collagen, or cellulose-lignin materials can effectively adsorb nearly 100% of harmful metals such as arsenic, cadmium, mercury, lead, and chromium (As, Cd, Hg, Pb, Cr) from wastewater while also effectively removing color. Enhancing therapeutic efficacy, longevity, safety, and cost-effectiveness requires research into these methods.
Physical and biochemical response of red and white dragon fruit under different temperature
Authors: Tanpure Pratik Sambhaji , Johar Vishal , Salunkhe Vanita N . , Singh Vikram , Thorat Deepak
Published: December 2024

The present study was planned at the School of Agriculture, Lovely Professional University, Phagwara (Punjab). It was conducted at the ICAR-National Institute of Abiotic Stress Management (ICAR-NIASM), Baramati (Pune). To determine the physicochemical response of red and white dragon fruit at different storage temperatures, we laid out the experiment in a completely randomized block design with four replications, each containing five fruits. The results revealed that white dragon fruit had a better fruit length (78.81 cm), fruit diameter (67.46 cm), fruit weight (198.60 g), etc., over red dragon fruit at room temperature. Under refrigerated temperature, we also reported similar results for fruit length (76.83 cm), fruit diameter (65.30 cm), and fruit weight (192.40 gm.). However, red dragon fruit performed better than white dragon fruit in terms of biochemical parameters such as TSS (11.95 °Brix), non-reducing sugar (4.33%), reducing sugar (4.67%), total phenol (296.7 mg/GAE/100 gm.), and total flavonoids (92.00 mg CE/100 g). The current study could aid in determining the ideal temperature for fruit storage, thereby reducing post-harvest losses in dragon fruit and potentially doubling the farmers' income.
1st SpatialData Developer Workshop
Authors: Marconato Luca , Vierdag Wouter-Michiel , Yamauchi Kevin , Mah Clarence , Crowell Helena , Blampey Quentin , Rombaut Benjamin , Keller Mark S , Pollaris Lotte , Dong Estella Yixing , Stockhaus Sonja , Lehner Laurens , Schiller Chiara , Bokota Grzegorz , LI Tong , Ibarra Miguel , Manukyan Artur , Righelli Dario , Deconick Louise , Carey Vincent J
Published: December 2024

This pre-print is aimed at sharing the results of the "1st SpatialData workshop," an in-person event organized by the SpatialData team and funded by the Chan Zuckerberg Initiative (CZI) that brought together expertise from different fields, including methods developers of a variety of tools for single-cell and spatial omics. The purpose is to explore new directions to advance the field of spatial omics. By leveraging multiple programming languages, including Python, R, and JavaScript, the event focuses on four central hackathon tracks: R interoperability: This track aims to enhance the integration and compatibility of R and Python with the SpatialData Python framework by using the language-agnostic SpatialData Zarr file format (which follows, when possible, the NGFF specification). Visualization interoperability: This track is dedicated to improving the seamless integration of visualization tools across different systems and programming languages via a tool-agnostic view configuration. Scalability and benchmarking: Participants will identify, benchmark, and address computational bottlenecks within the SpatialData framework. Ergonomics and user-friendliness: This track focuses on enhancing the usability and accessibility of the SpatialData framework for both first-time users and third-party developers. These tracks aim to foster collaboration and innovation, driving advancements in the analysis and infrastructure of spatial omics and imaging data.
ClassTiger: Ambiente Virtual de Aprendizagem gamificado para o ensino de Matemática
Authors: Santos Victor Cézar Scerni , Silva Ana Kely Martins da , Pereira Cinthia Cunha Maradei
Published: December 2024

Este artigo investiga a aplicação da gamificação combinada às Tecnologias Digitais de Informação e Comunicação (TDIC) como estratégia de ensino de matemática, voltada para engajar estudantes e apoiar a prática pedagógica. O objetivo é apresentar o ClassTiger, um aplicativo desenvolvido como parte de um produto educacional do Mestrado Profissional em Ensino de Matemática do (PPGEM/UEPA), que incorpora elementos de gamificação para apoiar o ensino de matemática de forma interativa. A metodologia incluiu uma revisão de literatura sobre gamificação e tecnologias digitais aplicadas à matemática, além do desenvolvimento do ClassTiger em uma plataforma No-Code (Bubble). Os resultados iniciais sugerem que o ClassTiger pode favorecer a personalização das atividades pelos professores e promover o trabalho colaborativo dos alunos, utilizando missões e desafios que auxiliam no desenvolvimento do raciocínio lógico e na construção coletiva do conhecimento matemático.
A study on the performance of a queuing system with heterogeneous arrivals and various types of breakdowns under multiple working vacations
Authors: Lidiya P  , K Julia Rose Mary
Published: December 2024

The paper analyses the performance of a single server queue with heterogeneous arrivals and various types of breakdowns under multiple working vacations. Customers enter the queue according to a Poisson process with a rate that varies according to the types of customers. In both the regular busy and working during the vacation states, the server offers services with an exponential distribution. During peak times, the system may breakdown due to server unavailability, the system may breakdown at any time. The model considers systems with two types of breakdowns. In this model, batches of customers are served under the General Bulk Service Rule. The steady-state equations, the performance of measures for the systems, and particular cases of the described model are derived. Finally, in the form of tables and graphs, numerical results have been obtained.
Triangular fuzzy numbers for satisfactory quality-environmental decisions in product development
Authors: Siwiec Dominika , Gawlik Remigiusz , Pacana Andrzej
Published: December 2024

The paper presents a novel MCDM model aimed at enhancing satisfactory quality-environmental decisions in product development. The model integrates FAHP, FTOPSIS, Pareto–Lorenz and global sensitivity analyses. It enables to study products with respect to quality level, environmental impact throughout its life cycle and simultaneous consideration on quality level and environmental impact. Results of the research on the example of a smartphone demonstrate that the model successfully identified specific criteria for improvement, offering a valuable tool for enhancing customer satisfaction and promoting environmentally friendly product development. The originality of the research lies in the calculation of the average weights of product criteria with triangular fuzzy numbers, based on the principles of fuzzy logic and FAHP. As a compact, ready-to-use solution, our innovative MCDM model can be employed by organizations to enhance the quality and environmental impact of their products.
On the Existence of Solutions to a Fractional Hybrid Thermostat Model
Authors: Saha Kiran Kumar , Sukavanam N.
Published: December 2024

This work is concerned with the existence of solutions to a nonlinear fractional hybrid thermostat model in the settings of Atangana-Baleanu derivatives. We also consider the boundary conditions of this model in the form of hybrid conditions. Imposing some suitable conditions on the given data, we establish the existence result of continuous solutions based on the Dhage fixed-point theorem in Banach algebra. Moreover, an example is constructed to illustrate our theoretical result.
On a General Subclass of q-Starlike and q-Convex Analytic Functions
Authors: Shammaky Amnah E. , Seoudy Tamer M.
Published: December 2024

We introduce a certain subclass of analytic functions in the open unit disk U involving the q-derivative operator. Some convolution results and Fekete-Szegö inequalities for the analytic functions belonging to this class are derived. We have also provided some results as corollaries of our theorems.
Nasopharyngeal Carcinoma in the Nias Tribe Indonesia: Prevalence, Risk Factors, and Characteristics
Authors: Hana Isal Salina Ginting  , Mery Silvia Harahap
Published: December 2024

Nasopharyngeal carcinoma (NPC) is a malignancy with a distinctive racial and geographical distribution, exhibiting a high prevalence in Southeast Asia, including Indonesia. The Nias tribe, an indigenous group in Indonesia, has a particularly high incidence of NPC, which may be linked to unique environmental and genetic factors. This study aimed to investigate the prevalence, risk factors, and characteristics of NPC among the Nias people to inform targeted prevention and control strategies. A retrospective study was conducted on 150 NPC patients treated at a referral hospital in Medan, Indonesia, between 2018 and 2023. Data were collected from medical records, including demographics, clinical presentation, Epstein-Barr virus (EBV) infection status, dietary habits, and environmental exposures. Descriptive statistics and comparative analyses were performed to identify risk factors associated with NPC in the Nias population. The prevalence of NPC among the Nias tribe was 30% (45 out of 150 NPC patients). The majority of Nias patients were male (60%) and aged 40-60 years (70%). EBV infection was prevalent in 80% of the Nias patients. Significant risk factors included consumption of preserved foods (78%), exposure to firewood smoke (65%), and a family history of NPC (20%). Most patients presented with advanced-stage disease (III and IV), with common symptoms such as neck lumps, epistaxis, and nasal obstruction. In conclusion, NPC poses a substantial health burden on the Nias tribe. EBV infection, consumption of preserved foods, exposure to firewood smoke, and genetic predisposition are significant risk factors. Public health interventions should prioritize early detection through EBV screening, health education on risk factors, and promotion of alternative cooking fuels to reduce exposure to carcinogens.
Preliminary Assessment of the Awareness Level of Radon and its Health Risks among High School Science Teachers and Health Workers in Nagongera, Tororo Uganda
Authors: Baniyo Nahori , Biira Saphina
Published: December 2024

This study aims to evaluate the awareness levels regarding radon, its associated health risks, and potential mitigation strategies among high school science teachers and health workers in Nagongera Sub County, Tororo District, Uganda. Tororo District, known for its rich natural mineral resources, particularly around the Osukuru Hills, has attracted numerous industries. The combination of mineral-rich geography and substandard building structures may elevate health risks for residents due to radon exposure. An instrumental case study approach was adopted, utilizing a questionnaire designed to assess the awareness of radon-related health risks alongside demographic information such as occupation. The study surveyed 30 health workers and 30 high school science teachers, totalling 60 respondents. Findings revealed that fewer than half of the health workers (30%) and high school science teachers (40%) were aware of radon as a radioactive substance and its health implications. These results highlight the need for targeted efforts by relevant authorities to improve radon awareness among the general population in the district
The Implementation of Infrastructure as Code Template for Low-cost Cloud Infrastructure Operations
Authors: Samuel Mumbere , Obira Okello Jimmy , Keneth Sansa
Published: December 2024

Cloud computing has emerged as a cornerstone of modern business operations, offering unmatched scalability, flexibility, and efficiency. However, migrating IT infrastructure to the cloud presents significant challenges, particularly for organizations with limited budgets, dependency on costly proprietary cloud tools, complex migration procedures, and a lack of technical expertise. These obstacles are especially evident in regions like Africa, where the adoption of cloud solutions remains restricted due to financial and technical barriers. This research tackles these challenges by developing and implementing an Infrastructure as Code (IaC) template tailored for cost-effective cloud infrastructure management, using Microsoft Azure as a case study.  The project developed and tested a reusable IaC template using tools like Terraform, Visual Studio Code, and Azure CLI. It optimized costs with a monitoring bash script that was executed on one of the Linux-based virtual machines that was created on the Azure portal during the implementation of IaC and ensured reliability via extensive validation thereby reducing the deployment time and costs by approximately 90% as compared to standard Azure configurations. The proposed solution harnesses open-source tools and industry best practices to streamline cloud resource deployment and management, reducing the reliance on expensive inbuilt services and lowering the technical barriers to cloud adoption. By automating the infrastructure provisioning process, the IaC template enables companies to efficiently manage their cloud environments, optimize costs by approximately 30% on infrastructure management, incur 0% costs on resource monitoring and maintain flexibility. The initiative is focused on empowering businesses in resource-constrained environments to take full advantage of cloud computing capabilities without incurring prohibitive expenses. It addresses key issues such as budget constraints, technical complexities, and inefficient management practices, providing a pathway for wider cloud adoption in economically developing regions. The research contributes valuable insights into how organizations can achieve low-cost, scalable, and efficient cloud infrastructure operations. The findings have the potential to significantly impact cloud technology adoption across various industries, enabling companies, particularly in developing regions, to leverage cloud solutions to enhance their competitiveness and operational efficiency
„Poesie, die sich selbst spiegelt, und nicht Gott“
Authors: Küpper Achim
Published: December 2024

Mit dem Verlust eines geistigen und religiösen Zentrums geht in letzter Konsequenz die Selbstbezüglichkeit der Kunst einher. Diesen Zusammenhang stellt Achim Küpper anhand des literarischen Werks von E.T.A. Hoffmann dar. Durch die äußerst detailgenaue Analyse der beiden Erzählungen „Das Fräulein von Scuderi“ und „Doge und Dogaresse“ liefert der Verfasser in der Diskussion um die ‚Modernität‘ des Autors eine bislang unbekannte Fülle an Belegen.Die Studie deckt ein umfassendes Gesamtsystem von literarischen und außerliterarischen Verweisen auf, macht immanente Bezugnahmen auf andere Werke als verborgene Wege der Selbstreflexion in Hoffmanns Texten sichtbar. Der Interpret stößt dabei auf Widersprüche, weist Bruchstellen im Inneren der Texte nach, die gerade jenen Ort bezeichnen, wo „nicht Gott“ ist, und die auch vor dem Hintergrund der Zeit um 1800, ihrer Umbrüche und Erschütterungen gelesen werden, ohne sie allerdings auf diesen einen historischen Ursprung zu fixieren. Auf diese Weise beschreibt die vorliegende Studie an Hoffmanns Werk zum ersten Mal das Erscheinen einer „Poesie, die sich selbst spiegelt, und nicht Gott“.
THE REALITY AND PROSPECTS OF CYBERCRIMES AND THE EXTENT OF AWARENESS OF INTERNET USERS IN LIBYA
Authors: Saed Alatrash Aisha
Published: December 2024

The use of the internet and information and communication technologies has been increasing significantly in Libya. Additionally, different social and economic activities are conducted online every day. As a result, this has led to critical concerns about the issue of cybercrime. Furthermore, the risks of cybercrimes vary and can cause economic and social harm, which can reach a high level. Therefore, this study aimed to introduce the reality of cybercrime in Libya and its prospects. As well as investigating the knowledge and awareness of internet users in Libya about this type of crime. The methodology used in this study was a questionnaire that targeted internet users in order to collect their knowledge about cybercrimes. There were 120 participants in the study. Additionally, the collected data were analyzed using SPSS (Statistical Package of Social Science). The results of this study showed that cybercrime exists in Libya. Although the discovered cybercrimes were not that dangerous, the potential of their spread and development is highly anticipated with the increasing involvement of technologies in all life activities. The results also showed that there are internet users in Libya who lack sufficient knowledge of the significant danger that cybercrimes could cause. Accordingly, the researcher presented some recommendations that could help eliminate the risk of cybercrime and protect internet users' data and privacy.
A Possible Pharmacotherapy-Avoiding Break-Through in Physical Therapy Treatment during Early Rehabilitation of Patients with High Muscle Tone after Thalamus Hemorrhage
Authors: Van Loon Olaf R. , Van Loon A. J. (Tom)
Published: December 2024

Deep dry needling (DDN) treatments were given during early rehabilitation to a 48-year-old male subject who suffered from brain hemorrhage with the objective to diminish hypertension. DDN treatment at such an early stage of recovery has not been well documented until now. It is new in, among some other aspects, that it avoids the commonly applied pharmacotherapy that is intended to decrease the hypertension, but that often appears hardly effective or not effective at all, or sometimes possibly even counter-effective. A pre-intervention test was performed to record baseline values, and the same aspects were measured again, directly after, and approximately one hour after the intervention. The results for the range of movement (ROM) of the subject’s right-side extremities were assessed through the Tardieu scale. It could be deduced that DDN did not result in a long-lasting reduction of the tension, but that the ROM values for the elbow joints within the treated muscles improved significantly during and immediately after the treatment, allowing better alignment and more active movement. It thus appeared that the DDN-induced temporarily improved ROM facilitated treatment and allowed the subject to exercise in a better alignment and more effectively during treatment. The experience with the subject makes it likely that DDN during early rehabilitation makes a post-stroke subject more comfortable (because of reduced spasticity/hypertension) and helps making physical therapy treatment of post-stroke patients more effective although no spasticity-reducing pharmacotherapy need be given, thus also increasing the cost-effectiveness of the treatment.
Applying Compiling Techniques in DTD Conversion
Authors: Tawk Souheil , Assaf Maroun Abi , Constantin Joseph , Barbar Kablan , Abdo Jacques Bou
Published: December 2024

In this paper, we propose to apply compilation techniques to Documents Type Definition (DTD). At the syntactic level, we create a context free grammar, denoted GDT D , for the set of all DTDs in order to generate them. The semantic level is defined by using attributes. Each nonterminal of GDT D is assigned a set of attributes and for each production of GDT D a set of attribute equations is defined. This DTD compilation process can be used in different domains. In this article, we provide an attribute grammar that can be used to eliminate unnecessary parentheses in element declarations in a DTD. In addition, the DTD compilation process can be applied to the domain of model conversion. It makes it possible to split the model conversion into two steps: the syntactic transformation step, which consists of rewriting the source DTD in terms of XML syntax, and the second step of the effective conversion algorithm, which can be easily expressed by an Extensible Stylesheet Language Transformation (XSLT).
Redescription of the type specimen of Csakvaromys sciurinus (Rodentia, Sciuridae, Xerinae) from the Late Miocene of Hungary and its bearing on the systematics of early ground squirrels
Authors: Sinitsa Maxim V. , Čermák Stanislav
Published: December 2024

Csakvaromys sciurinus is an enigmatic stem ground squirrel from the Late Miocene of Hungary that has previously only been briefly described. The restudy of the holotype allows a detailed redescription and comparison with different xerines. Csakvaromys sciurinus is recognized as a junior synonym of Csakvaromys bredai and diagnosed by the following combination of characters: medium size, close to the maximum limits of C. bredai; massive body of the mandible with deep diastemal portion and shallow diastemal depression; elevated area of the mental foramen; nonconfluent lower and upper masseteric crests separated by the attachment area for the anterior fibers of the anterior deep masseter muscle; transversely compressed lower incisor with longitudinally striated anterior enamel face; and brachyodont cheek teeth with mesoconids, rudimentary entoconids, and well-developed anteroconulid of p4.
Herpetotheriidae, Talpidae, and Erinaceidae from the Early Miocene fissures of Mokrá-Quarry (South Moravia, the Czech Republic)
Authors: Bonilla-Salomón Isaac , Cailleux Florentin , Joniak Peter , Ivanov Martin , Sabol Martin
Published: December 2024

Fossils of Metatheria and Eulipotyphla from the karstic fissures MWQ2/2003, MCQ3/2005 and MWQ4/2018 of Mokrá-Quarry (South Moravia, the Czech Republic) are studied. These Early Miocene fissures have yielded remains of the herpetotheriid Amphiperatherium frequens, together with the erinaceids Amphechinus cf. baudeloti, Galerix exilis, and G. symeonidisi. The talpid Talpa sp. has also been identified. The rare remains of Amphiperatherium frequens represent the first description of this species from the Early Miocene of the Czech Republic. The erinaceid Amphechinus cf. baudeloti could be a convenient structural ancestor of A. baudeloti, although the scarcity of remains hampered a clear taxonomic verdict. In addition, the relatively abundant remains of Galericinae in the studied fissures made it possible to identify a mixture of two Galerix species, G. exilis and G. symeonidisi. Their cooccurrence is evidenced at least in MWQ2/2003. The dentognathic and postcranial remains of Talpidae clearly point to Talpa sp. The relatively low diversity of insectivores recovered from Mokrá-Quarry fissures agree with previous studies concerning the paleoenvironmental reconstruction, depicting Mokrá-Quarry as a dry karst plateau close to water bodies and patches of woodland. The wide range of small mammal species found in Mokrá-Quarry fissures suggests a diverse regional environment, making Mokrá-Quarry a reference locality in the Early Miocene of Central Europe.
Nomination of a lectotype for the avian oospecies Psammornis rothschildi Andrews, 1912
Authors: Pickford Martin , Russell Douglas , Day Michael O.
Published: December 2024

Psammornis rothschildi is an avian oospecies, the type material of which was collected from the desert surface in 1909 (i.e., without stratigraphic context), 20 miles east of Touggourt, Algeria. At 3.2–3.3 mm thick, the eggshell is considerably thicker than those of extant ostriches. Thin sections of the eggshell have been illustrated, and descriptions of the surface features are available, but these have not included images of the external and internal surfaces. This lack has caused uncertainty among authors who have dealt with other occurrences of the taxon, because it has rendered it difficult to compare specimens from other localities with the type material. In order to rectify the situation, images of the original specimens are provided, their curation history is summarised, and a lectotype is nominated so as to stabilise the nomenclature.
Terrestrial artiodactyl remains from the whale horizon at Groß Pampau (ancient North Sea Basin, North Germany; Serravallian-Tortonian boundary, Middle-Late Miocene)
Authors: Rössner Gertrud E. , Hampe Oliver
Published: December 2024

The mica-clay fossil site Groß Pampau is famous for its later Miocene marine mammal record, which represents the fauna of the then-southern North Sea Basin. Since the 1980s, fossils have been collected and later systematically excavated. For a long time, only marine taxa were identified. In 2017, two nicely preserved remains of terrestrial artiodactyls were discovered as the so far only terrestrial input and northernmost European terrestrial mammal record of the pre-Quaternary Cenozoic. Here, we figure, describe, and compare morphology and dimensions of both specimens. We identified them as fragment of a hemimandible with two lower molars and a distal phalanx of a cervid, but were unable to assign them to a genus or species, due to limited contemporaneous comparative material.
Praktik Akad Mudharabah Kontemporer Pada Perbankan Syariah Indonesia
Authors: Kartika  , Sabbar Dahham Sabbar
Published: December 2024

The modern economic era requires Islamic banking to create financial products that are competitive, transparent, and in accordance with sharia principles, including the implementation of mudharabah contracts. The transformation of mudharabah contracts from classical to contemporary forms reflects the efforts of Islamic banking to meet market demands while maintaining sharia values. This study aims to identify the characteristics of mudharabah contract transformation in Indonesian Islamic banking, analyze the obstacles faced, and explore strategies that can be implemented to improve its effectiveness. The research method uses a descriptive qualitative approach with a literature study through document analysis and secondary data related to mudharabah practices in Indonesia. The results show that the transformation of the mudharabah contract includes technical adjustments such as the application of revenue sharing, the introduction of collateral, and limiting the freedom of mudharib through mudharabah muqayyadah. However, the implementation of this contract still faces challenges in the form of moral hazard risk, non-uniform regulations, and public resistance to the principle of profit sharing. Theoretically, this research contributes to the literature of Islamic economics, especially in the development of an adaptive Islamic contract model that is consistent with maqashid sharia. Practically, this study offers guidance for Islamic banks in designing mudharabah-based products, education for the public to improve their understanding of the principle of profit sharing, and recommendations for regulators in strengthening regulations. This study concludes that the success of mudharabah contracts requires strengthening regulations, product innovation, and more intensive public education, so as to increase the competitiveness of Islamic banking in Indonesia.