bluuebunny/crossref_metadata_2025 huggingface dataset:
Investigating autism associated genes in C. elegans reveals candidates with a role in social behaviour
Authors: Rawsthorne Helena , Calahorro Fernando , Holden-Dye Lindy , O’ Connor Vincent , Dillon James
Published: May 2021

Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterised by a triad of behavioural impairments and includes disruption in social behaviour. ASD has a clear genetic underpinning and hundreds of genes are implicated in its aetiology. However, how single penetrant genes disrupt activity of neural circuits which lead to affected behaviours is only beginning to be understood and less is known about how low penetrant genes interact to disrupt emergent behaviours. Investigations are well served by experimental approaches that allow tractable investigation of the underpinning genetic basis of circuits that control behaviours that operate in the biological domains that are neuro-atypical in autism. The model organismC.elegansprovides an experimental platform to investigate the effect of genetic mutations on behavioural outputs including those that impact social biology. Here we use progeny-derived social cues that modulateC.elegansfood leaving to assay genetic determinants of social behaviour. We used the SAFRI Gene database to identifyC.elegansorthologues of human ASD associated genes. We identified a number of mutants that displayed selective deficits in response to progeny. The genetic determinants of this complex social behaviour highlight the important contribution of synaptopathy and implicates genes within cell signalling, epigenetics and phospholipid metabolism functional domains. The approach overlaps with a growing number of studies that investigate potential molecular determinants of autism inC.elegans. However, our use of a complex, sensory integrative, emergent behaviour provides routes to enrich new or underexplored biology with the identification of novel candidate genes with a definable role in social behaviour.
Perspectives of nurses’ role in interprofessional pharmaceutical care across 14 European countries: A qualitative study in pharmacists, physicians and nurses
Authors: De Baetselier Elyne , Dilles Tinne , Batalha Luis M. , Dijkstra Nienke E. , Fernandes Maria I. , Filov Izabela , Friedrichs Juliane , Grondahl Vigdis A. , Heczkova Jana , Helgesen Ann Karin , Jordan Sue , Keeley Sarah , Klatt Thomas , Kolovos Petros , Kulirova Veronika , Ličen Sabina , Lillo-Crespo Manuel , Malara Alba , Padysakova Hana , Prosen Mirko , Pusztai Dorina , Riquelme-Galindo Jorge , Rottkova Jana , Sino Carolien G. , Talarico Francesco , Tziaferi Styliani , Van Rompaey Bart
Published: May 2021

Objectives

To understand healthcare professionals’ experiences and perceptions of nurses’ potential or ideal roles in pharmaceutical care (PC).

Design

Qualitative study conducted through semi-structured in-depth interviews.

Setting

Between December 2018 and October 2019, interviews were conducted with healthcare professionals of 14 European countries in four healthcare settings: hospitals, community care, mental health and long-term residential care.

Participants

In each country, pharmacists, physicians and nurses in each of the four settings were interviewed. Participants were selected on the basis that they were key informants with broad knowledge and experience of PC.

Data collection and analysis

All interviews were conducted face to face. Each country conducted an initial thematic analysis. Consensus was reached through a face-to-face discussion of all 14 national leads.

Results

340 interviews were completed. Several tasks were described within four potential nursing responsibilities, that came up as the analysis themes, being: 1) monitoring therapeutic/adverse effects of medicines, 2) monitoring medicines adherence, 3) decision making on medicines, including prescribing 4) providing patient education/information. Nurses’ autonomy varied across Europe, from none to limited to a few tasks and emergencies to a broad range of tasks and responsibilities. Intended level of autonomy depended on medicine types and level of education. Some changes are needed before nursing roles can be optimised and implemented in practice. Lack of time, shortage of nurses, absence of legal frameworks and limited education and knowledge are main threats to European nurses actualising their ideal role in PC.

Conclusions

European nurses have an active role in PC. Respondents reported positive impacts on care quality and patient outcomes when nurses assumed PC responsibilities. Healthcare professionals expect nurses to report observations and assessments. This key patient information should be shared and addressed by the interprofessional team. The study evidences the need of a unique and consensus-based PC framework across Europe.
Efficacy and cost of high-frequency IGRT in elderly stage III non-small-cell lung cancer patients
Authors: Heilbroner Samuel P. , Xanthopoulos Eric P. , Buono Donna , Carrier Daniel , Durkee Ben Y. , Corradetti Michael , Wang Tony J. C. , Neugut Alfred I. , Hershman Dawn L. , Cheng Simon K.
Published: May 2021

Background

High-frequency image-guided radiotherapy (hfIGRT) is ubiquitous but its benefits are unproven. We examined the cost effectiveness of hfIGRT in stage III non-small-cell lung cancer (NSCLC).

Methods

We selected stage III NSCLC patients ≥66 years old who received definitive radiation therapy from the Surveillance, Epidemiology, and End-Results-Medicare database. Patients were stratified by use of hfIGRT using Medicare claims. Predictors for hfIGRT were calculated using a logistic model. The impact of hfIGRT on lung toxicity free survival (LTFS), esophageal toxicity free survival (ETFS), cancer-specific survival (CSS), overall survival (OS), and cost of treatment was calculated using Cox regressions, propensity score matching, and bootstrap methods.

Results

Of the 4,430 patients in our cohort, 963 (22%) received hfIGRT and 3,468 (78%) did not. By 2011, 49% of patients were receiving hfIGRT. Predictors of hfIGRT use included treatment with intensity-modulated radiotherapy (IMRT) (OR = 7.5, p < 0.01), recent diagnosis (OR = 51 in 2011 versus 2006, p < 0.01), and residence in regions where the Medicare intermediary allowed IMRT (OR = 1.50, p < 0.01). hfIGRT had no impact on LTFS (HR 0.97; 95% CI 0.86–1.09), ETFS (HR 1.05; 95% CI 0.93–1.18), CSS (HR 0.94; 95% CI 0.84–1.04), or OS (HR 0.95; 95% CI 0.87–1.04). Mean radiotherapy and total medical costs six months after diagnosis were $17,330 versus $15,024 (p < 0.01) and $71,569 versus $69,693 (p = 0.49), respectively.

Conclusion

hfIGRT did not affect clinical outcomes in elderly patients with stage III NSCLC but did increase radiation cost. hfIGRT deserves further scrutiny through a randomized controlled trial.
Characterization of oral and cloacal microbial communities in cold-stunned Kemp’s ridley sea turtles (Lepidochelys kempii) during the time course of rehabilitation
Authors: McNally Kerry L. , Innis Charles J. , Kennedy Adam , Bowen Jennifer L.
Published: May 2021

Microbial communities of animals play a role in health and disease, including immunocompromised conditions. In the northeastern United States, cold-stunning events often cause endangered Kemp’s ridley turtles (Lepidochelys kempii) to become stranded on beaches in autumn. These sea turtles are admitted to rehabilitation facilities when rescued alive and are presumed immunocompromised secondary to hypothermia. To better understand the role that microbes play in the health of cold-stunned sea turtles, we characterized the oral and cloacal microbiome from Kemp’s ridley turtles at multiple timepoints during rehabilitation, from admission to pre-release, by using Illumina sequencing to analyze the 16S rRNA gene. Microbial communities were distinct between body sites and among turtles that survived and those that died. We found that clinical parameters such as presence of pneumonia or values for various blood analytes did not correlate with oral or cloacal microbial community composition. We also investigated the effect of antibiotics on the microbiome during rehabilitation and prior to release and found that the type of antibiotic altered the microbial community composition, yet overall taxonomic diversity remained the same. The microbiome of cold-stunned Kemp’s ridley turtles gradually changed through the course of rehabilitation with environment, antibiotics, and disease status all playing a role in those changes and ultimately the release status of the turtles.
Early release from prison in time of COVID-19: Determinants of unfavourable decisions towards Black prisoners
Authors: Miranda Mariana P. , Costa-Lopes Rui , Freitas Gonçalo , Carvalho Catarina L.
Published: May 2021

On the onset of the COVID-19 pandemic, the overcrowding in prisons led to efforts to decarcerate in order to prevent and control outbreaks in prisons. This study analyses how public support for such exceptional measures are determined by cognitive and ideological factors known to create and maintain racial biases in the criminal system. Participants were asked to express their level of agreement with the early-release of hypothetical prisoners. Results showed participants to be less favourable to the early-release of Black compared to White prisoners, when they had committed a stereotypically Black crime. As expected, the congruency between the crime stereotypicality and the colour of the prisoner’s skin did not emerge for White prisoners. Moreover, the difference between the agreement with the release of the Black vs. the White prisoner when both committed a stereotypically Black crime was higher as the level of endorsement of Meritocracy increased. Contrastingly, Anti-egalitarianism only predicted an overall disagreement with prisoners’ early-release. This paper highlights the cumulative explanation by different levels of analysis of this current problem and implications for the development of the public opinion on penal subjects.
Herb-partitioned moxibustion alleviates colonic inflammation in Crohn’s disease rats by inhibiting hyperactivation of the NLRP3 inflammasome via regulation of the P2X7R-Pannexin-1 signaling pathway
Authors: Zhang Ji , Wang Xue-jun , Wu Li-jie , Yang Ling , Yang Yan-ting , Zhang Dan , Hong Jue , Li Xi-ying , Dong Xiao-qing , Guo Xiao-cong , Han Rong , Ma Xiaopeng
Published: May 2021

Crohn’s disease is a chronic inflammatory bowel disease and the NLRP3 inflammasome plays an important role in Crohn’s disease. Previous studies have shown that Herb-partitioned moxibustion treating (at Qihai (CV 6) and Tianshu (ST 25)) prevented the excessive activation of the NLRP3 inflammasome and repaired damaged colonic mucosa in Crohn’s disease. However, the mechanism by which Herb-partitioned moxibustion (at CV 6 and ST 25) regulates NLRP3 remains unclear. In this study, we treated Crohn’s disease rats with herb-partitioned moxibustion (at CV 6 and ST 25) to investigate the mechanism by which Herb-partitioned moxibustion regulates the colonic NLRP3 inflammasome by observing colon length, the colon macroscopic damage indexes, and the expression of ATP, P2X7R, Pannexin-1, NF-κBp65, NLRP3, ASC, caspase-1, IL-1β and IL-18 in the colon in Crohn’s disease. Here, this study shows that herb-partitioned moxibustion (at CV 6 and ST 25) can reduce colon macroscopic damage indexes and colon histopathological scores, alleviate colon shortening and block the abnormal activation of the NLRP3 inflammasome by inhibiting the ATP content and the expression of P2X7R, Pannexin-1 and NF-κBp65, thereby reducing the release of the downstream inflammatory cytokine IL-1β and ultimately suppressing colonic inflammation in Crohn’s disease rats. This study for the first time identifies the mechanism by which herb-partitioned moxibustion (at CV 6 and ST 25) may inhibit the abnormal activation of the NLRP3 inflammasome by inhibiting the P2X7R-Pannexin-1 signaling pathway in Crohn’s disease rats.
Venous malformation vessels are improperly specified and hyperproliferative
Authors: Schonning Michael J. , Koh Seung , Sun Ravi W. , Richter Gresham T. , Edwards Andrew K. , Shawber Carrie J. , Wu June K.
Published: May 2021

Venous malformations (VMs) are slow-flow malformations of the venous vasculature and are the most common type of vascular malformation with a prevalence of 1%. Germline and somatic mutations have been shown to contribute to VM pathogenesis, but how these mutations affect VM pathobiology is not well understood. The goal of this study was to characterize VM endothelial and mural cell expression by performing a comprehensive expression analysis of VM vasculature. VM specimens (n = 16) were stained for pan-endothelial, arterial, venous, and endothelial progenitor cell proteins; proliferation was assessed with KI67. Endothelial cells in the VM vessels were abnormally orientated and improperly specified, as seen by the misexpression of both arterial and endothelial cell progenitor proteins not observed in control vessels. Consistent with arterialization of the endothelial cells, VM vessels were often surrounded by multiple layers of disorganized mural cells. VM endothelium also had a significant increase in proliferative endothelial cells, which may contribute to the dilated channels seen in VMs. Together the expression analysis indicates that the VM endothelium is misspecified and hyperproliferative, suggesting that VMs are biologically active lesions, consistent with clinical observations of VM progression over time.
Teacher Quality and Teacher Education: A Critical Policy Analysis of International and Australian Policies.
Authors:   Griffith University, Singh Parlo , Hoyte Frances ,   Griffith University, Heimans Stephen ,   University of Queensland, Exley Beryl ,   Griffith University
Published: May 2021

This article examines how the ‘teacher quality’ agenda, evident in the globalised discourse on education policy, constructs changes to teachers’ work and teacher education. We undertake a critical policy analysis of two reportsfrom the Organisation for Economic Cooperation and Development (OECD), addressing three issues. First, we discuss the global and national context in which ‘teacher quality’ policies have emerged. We examine implications of policy enactment in Australia and analyse how the OECD documents construct understandings of teacher quality. We link our analysis to a recent government inquiry into the teaching profession in Australia, looking specifically at the impact of the teacher quality discourse on teacher education. The OECD documents constrain what is perceived as acceptable curriculum, pedagogy and evaluation in teacher education. We argue, with others, that changes in response to the teacher quality discourse are narrowing what it means to undertake quality teaching work,especially in contexts of disadvantage.
International Mobility of Serbian Citizens at the Outbreak of the COVID-19 Pandemic
Authors: Mirkov Anđelka , Poleti Ćosić Dunja
Published: May 2021

Research into the characteristics of the international mobility of Serbian
citizens who found themselves abroad at the outbreak of the COVID-19
pandemic was carried out by the Institute for Sociological Research of the
University of Belgrade – Faculty of Philosophy. The main goal of the research
was to explore the effects of the global health crisis on the international mobility
of Serbian citizens from their own perspective. In particular, the research aimed
to contribute to a better understanding of the reasons and modes of return to
the home country, experiences and problems during obligatory self-isolation, as
well as attitudes towards national responses to the pandemic.
Socio-psychological Implications of the Outbreak of COVID-19: Issues, Challenges and Future Prospects
Authors: Malla Manzoor Ahmad , War Hilal Ahmad
Published: May 2021

The epidemic outbreak of Corona-virus emerged in the capital of Hubei province of China in December 2019 has engulfed almost all the sections of the society across globe irrespective of age, sex, race, religion, and color. The exposure of Covid-19 has increased the risk of numerous problems like stress, disorder, unemployment, poverty and other numerous challenges. This paper talks about the socio-psychological implications pertaining to the spread of coronavirus and how it has caused deaths in lakhs and how developing cum developed countries alike have imposed lockdowns, curfews, restrictions on public movements, markets, workplace, constructions, and transport and instructed people to maintain social distance which has adversely affected the daily life of common masses; particularly the daily wage earners who have no other alternative to feed their respective family thereby putting them in a state of dilemma. Many health experts have given a warning that if the disease is not controlled, it will take a heavy toll on the global level. The paper discusses about the Covid-19 has created anxiety, stress, strain, confusion, trauma, mental health problems, violence against women, children and encourage the risks of suicidal behavior. It also talks about the effects of Covid-19 on the marginalized and poor sections of the society such as migrant workers, street vendors and daily wage labours and how keeping social distance, avoiding gathering, staying at home, avoid travelling, keeping away from doing daily routine work activities etc. are some of the important challenges faced by common masses.
The relationship between social media use, eating attitude and body mass index among nutrition and dietetic female students: A cross-sectional study
Authors: Güneş Fatma Esra , Aktaç Şule , Kargin Dicle
Published: May 2021

Introduction: This study aimed to investigate the relationship between media using habits, frequency and duration, and body mass index on eating attitudes. Material and methods: The cross-sectional study was conducted with female students who received nutrition and dietetics education in Istanbul. A questionnaire consisting of a socio-demographic questionnaire, Eating Attitude Test (EAT-40), and Social Media Attitude Scale was applied to 1248 female volunteers by the face-to-face interview method.Results: It was found that 35.7% of the participants had abnormal eating attitudes and 89.6% showed a positive attitude towards social media. 93.7% of the group with abnormal eating attitudes indicated a positive attitude towards social media, 0.4% had a negative attitude and the difference was statistically significant (p=0.001). It was observed that a significant difference between EAT-40 and thought of an eating problem, having a social media membership, and spending time on social media (p<0.05).Conclusions: Social media have an effect on nutrition dietetics students on abnormal eating attitude; it did not show a significant effect on BMI.
Prevalencia y factores asociados al consumo de suplementos nutricionales en asistentes a gimnasios de la Ciudad de México
Authors: Sánchez Rivera Ana Cristina , Ayala-Guzmán César Iván , López Roldán Ana Belem , Castro Ramírez Oscar David , Ortiz-Hernández Luis
Published: May 2021

Introducción: En México ha aumentado la proporción de personas que realizan ejercicio y de quienes consumen suplementos nutricionales (SN), lo cual podría implicar mayor riesgo de consecuencias no deseables para la salud, debido a que su uso no está regulado. Estudios previos han reportado la relación del uso de SN con características sociodemográficas y la experiencia u objetivos de entrenamiento de asistentes a gimnasios, pero no con indicadores de la autopercepción de la imagen corporal.
Material y métodos: Se realizó un estudio transversal con una muestra de 1.135 de adultos mexicanos de 18 a 40 años. Se indagó sobre hábitos de entrenamiento, de alimentación y de suplementación. Mediante modelos de regresión de Poisson se analizó la relación de características sociodemográficas, de entrenamiento y autopercepción de la imagen corporal con el uso de SN.
Resultados: 58,0% de los participantes fueron hombres y 42,0% fueron mujeres, 46,2% habían consumido algún SN y 35,4% lo consumía durante el estudio. Los SN más consumidos fueron bebidas deportivas (28,7%) y proteína (23,6%). El consumo de SN fue mayor en hombres, participantes de mayor edad, con más tiempo entrenando y con deterioro funcional por dismorfia muscular. Los nutricionistas fueron la tercera fuente que recomendó SN, después de entrenadores y amigos.
Conclusiones: Casi la mitad de los asistentes a gimnasios han consumido algún SN. Existen grupos que tienen mayor probabilidad de consumir SN, lo que puede requerir mayor indagación respecto a las razones que explican esto.
Einleitung
Authors: Engelhardt Nina , Schick Johannes F.M.
Published: May 2021

Nina Engelhardt und Johannes F.M. Schick widmen sich in der Einleitung einer Untersuchung des Zusammenspiels von Körper, Technik und Imagination, die in den Beiträgen des Bandes genauer untersucht werden. Sie betrachten, wie Körpertechniken oft fast unbemerkt ablaufen, jedoch in Zeiten des Umbruchs, wie etwa der Covid-19-Pandemie oder den Protesten der Black Lives Matter-Bewegung, größere Aufmerksamkeit erfahren und bewusst werden, und wie auch Kunst soziale Konventionen offenlegen kann. Das Erfinden neuer Techniken, sei es durch Anpassung inadäquat gewordener Praktiken oder Ermöglichung dessen, was vorher nur geträumt oder imaginiert werden konnte, zeigt das komplexe Geflecht von körperlich-leiblicher, technischer und imaginativer Arbeit besonders deutlich. Engelhardt und Schick situieren den Begriff »Imaginationstechniken« in der aktuellen Forschung, etwa zu 4E cognition und embodied simulation Theorie, und stellen die drei Abschnitte des Bands »Erfinden«, »Schöpfen, «Machen» vor.
Literarische Journalisten - Journalistische Literaten
Authors: Opitz Fanny
Published: May 2021

Während der hemdsärmelige Reporter lediglich für den Tag schreibt, schafft der Literat Texte für die Ewigkeit. Mit diesem über Jahrhunderte tradierten Klischee brechen zwei Autoren ganz bewusst, die in beiden Bereichen erfolgreich sind: Joseph Roth und Tom Wolfe - in Personalunion Journalisten wie Literaten - hinterfragen den Wertungsunterschied, der gemeinhin zwischen den Bereichen gemacht wird. Fanny Opitz zeichnet die diskursiven Umfelder nach, in denen die Debatte um die Leistung von Journalismus und Literatur breit geführt wurde: im Deutschland der 1920er Jahre im Kontext der gesamtkulturellen Strömung der Neuen Sachlichkeit und im US-amerikanischen New Journalism der 1960er und 1970er Jahre.
Zone Heimat 2.0? Heimat und Beheimatung unter dem Berliner Fernsehturm
Authors: Herold Stephanie
Published: May 2021

Stephanie Herold zeichnet in ihrem Beitrag die Diskussionen um mögliche Umgestaltungen des sogenannten Berliner Rathausforums zwischen Fernsehturm und Spree seit den 1990er Jahren nach und bringt sie, in Anknüpfung unter anderem auf Gerhard Vinkens Arbeit zu rekonstruierten Altstädten als Zone Heimat (2008), mit verschiedenen Konzepten von Heimat und Erbe in Bezug. Dabei spielen nicht nur die verschiedenen Vorstellungen von Heimat als imaginiertem Ort eine Rolle, sondern auch von Heimat als Ausdruck von Mitsprache und Teilhabe im Sinne einer aktiven Beheimatung. So stellt sich die Frage, ob es nicht gerade die dargestellten Diskussionen und Auseinandersetzungen um das Vorhandene und das nicht (mehr) Vorhandene, um Geschichte und Erinnerung, um Denkmale und Erbe sind, die an diesem Ort das Potenzial auch für neue Möglichkeiten der Beheimatung schaffen.
Reflexive Kataloge
Authors: Felsing Ulrike
Published: May 2021

Für gewöhnlich präsentieren Ausstellungskataloge das Kunstwerk als von Zeit und Raum losgelöste Reproduktion. Die visuelle Reflexion und die mediale Übersetzung gewinnen jedoch zunehmend an Bedeutung: Neue Bedürfnisse in der Dokumentation von Installations- und Konzeptkunst, die rasante Verbreitung des Internets sowie der damit verbundene Innovationsdruck auf das klassische Buch lassen auch neue Katalogformen entstehen. Ulrike Felsing stellt diese Reflexiven Kataloge vor, die raumbezogene, film- und hypertextartige Präsentationsformen nutzen, um relevante Zusammenhänge zu vermitteln.
Die Gabe als drittes Prinzip zwischen Markt und Staat?
Authors: Frick Marc
Published: May 2021

Marcel Mauss schrieb 1923 in seinem Essay Die Gabe, er habe in den Motiven des Gabentauschs »einen der Felsen gefunden, auf denen unsere Gesellschaften ruhen«. Bis heute wirft diese These Fragen auf: Wie stiftet die Gabe Solidarität, Anerkennung und Vertrauen in vormodernen Gesellschaften? Gelingt ihr das auch in modernen Gesellschaften? Aufbauend auf einer pointierten Rezeptionsgeschichte von Mauss' Essay und im Dialog mit Denkern aus Philosophie, Politik- und Wirtschaftswissenschaften kommt dieses Buch zu dem Ergebnis, dass die Gabe neben Markt und Staat eine zentrale Funktion in unserer Gesellschaft hat. Darüber hinaus wird gezeigt, welche politischen Konsequenzen daraus resultieren und wie Gabeninteraktionen zur Sicherung des sozialen Gefüges genutzt werden können.
Einleitung
Authors: Hitzke Diana
Published: May 2021

Diana Hitzke widmet sich in diesem einleitenden Beitrag der Frage nach Konzeptualisierungen kleiner (europäischer) und nicht-westlicher Kulturen. Sowohl künstlerische als auch epistemologische Konzepte sind von kulturspezifischen Narrativen und Strukturen sowie durch globale Machtverhältnisse geprägt. Die Dominanz westlich geprägter Konzepte in globalen Diskursen führt oft zu einer verzehrten Wahrnehmung andersartiger oder widersprechender Narrative, Entwicklungen, Strukturen und Praktiken: Statt ihre Einzigartigkeit und Innovationskraft zu beschreiben, werden sie als Fallbeispiele und Sonderfälle dargestellt. Der Beitrag beschreibt den Forschungsstand zu diesen Fragen, zeigt neue Perspektiven sowie methodische Lösungen auf und bietet eine Zusammenfassung der im Tagungsband versammelten Beiträge.
Offen und entschieden: die idiosynkratische Radikalität der Kunst
Authors: Schaub Mirjam
Published: May 2021

Der Kunstdiskurs, der sie umschmeichelt, in schöne Worte kleidet oder gelehrt um ihre möglichst mannigfaltigen Bedeutungen streitet, verkennt und verschleiert - so die These - dass Kunstwerke selbst erstaunlich entschieden sind. Sie treffen, so sie gut und nicht bloß angenehm sind, ihre Betrachter_innen mit einer Erkenntnis, die gerade nicht diskursiv vermittelt ist, oft hart und mitten ins Gesicht, wie eine Beleidigung von unerwarteter Seite. Gilles Deleuze nannte diese Eigenschaft, perzeptiv und eben nicht funktionell oder konzeptuell, zu wirken und so das Chaos der Möglichkeit einzuhegen, etwas, das zum Denken zwingt. Ist diese Entschiedenheit nicht trotz, sondern aufgrund ihrer inhärenten Einseitigkeit attraktiv? Erklärt sie die der Kunst eigene Radikalität, welche Plessner als die „Verunendlichung einer Idee» charakterisierte? Der Artikel geht dieser Fährte nach und versucht eine Kritik an Umberto Ecos vielzitierter Rede von der „Offenheit der Kunstwerke» zu leisten.
Film als Gegenverwirklichung
Authors: Salhab Ghassan , Ott Michaela
Published: May 2021

Ghassan Salhab, Filmemacher und Essayfilmer aus Beirut im Gespräch mit Michaela Ott, Ästhetiktheoretikerin und Philosophin aus Berlin. Anlässlich von Salhabs jüngstem, 2019 in Berlin gedrehtem Film "Une rose ouverte/Warda" sprechen sie über Identität und das Kompositkulturelle, da Salhab sich affirmativ zwischen Senegal, Libanon und Frankreich/Deutschland bewegt und gegen kulturell vereindeutigte Setzungen ausspricht. Sein essayistischer Film versteht sich als Hommage an Rosa Luxemburg und ihr Plädoyer für die internationale Revolution. Dieser beunruhigenden Dringlichkeit möchte er sich stellen, auch wenn die Begegnung zu groß für ihn sei, weshalb er sich ihr assoziativ zu nähern sucht: in filmischer Verdichtung von Theorien, Texten u.a. von Celan und Beckett, Bildern deutscher und libanesischer Landschaft. Wichtig sei ihm, die raumzeitliche Situiertheit der Aussage in ein horizontales Nebeneinander zu überführen, Luxemburgs Forderung in visuellen und auditiven Resonanzen zu evozieren, ungleichzeitige Bilder und Töne zu amalgamieren, in passiv-aktiven Vorgehensweisen, da Passivität immer von Passionellem zeugt. Kunst sei daher mit Deleuze als Gegenverwirklichung zu verstehen.
Situierte Formen: Kunst, Sprache und die Frage nach ihren Eigenlogiken / Situated Forms: Thoughts on Arts, Language and their Intrinsic Logics
Authors: Magauer Hanna
Published: May 2021

Allen Bezüglichkeiten zum Trotz wurde in kunstwissenschaftlichen Debatten die künstlerische Form häufig als ein dem Politischen entgegengesetztes Element behandelt: Auf der einen Seite wurden durch Formen geschaffene Relationen wie Bild- oder Stilzitate oft kunstimmanent diskutiert, als einer anderen Logik gehorchend und damit scheinbar unabhängig von ihrem sozialen Kontext. Auf der anderen Seite stand eine solche Formanalyse und Stilkritik häufig unter dem Verdacht, von dringlicheren politischen Fragen der Kunst abzulenken. Was bedeutet es also für ‚Formensprachen', wenn man sie im Spannungsfeld zwischen Kunst, Wissen und sozialen Handlungen liest? Und was heißt das für die Sprache, mit der Forschende über künstlerische Arbeiten sprechen oder schreiben? In Dialog mit anderen Beiträgen aus dem Band geht der Text den spezifischen Situiertheiten nach, die sich auch in einem relationalen Blick auf die Künste manifestieren.
Design of Magnetic Focusing system for a Compact Ka band Helix TWT
Authors: Kumar Mithilesh , Geetha M.K. , Kumar M. Vijay
Published: May 2021

In this paper we discuss the design of Magnetic focusing system (MFS) for a compact helix travelling wave tube (TWT) operating in Ka-band. Issues related to the design of the magnetic focusing system have been discussed in detail along with practical measurement results. The key design parameters considered for this TWT are: the cathode voltage is around 9.3kV, beam current is 200mA and total length of the tube not more than 6 inch with minimal weight.
Output System of a 42 84 GHz 0.5 MW Dual Regime Gyrotron
Authors: Baghel Gaurav Singh , Kartikeyan M. V.
Published: May 2021

In this paper, the design studies of the output system are carried out for a dual regime Gyrotron in the context of India’s requirement of clean energy. This design study consists of a dimpled wall quasi-optical launcher (QOL) and RF window. After proper coupling of energy from beam to RF wave, the amplified wave need to be down-convert in a Gaussian-like beam (much simplified lower order). The launcher is designed with a commercial software LOT/Surf3d. This Gaussian-like mode coming out from the gyrotron vacuum system through the RF window is coupled to the corrugated waveguide using Matching Optic Unit (MOU) section. The complete design of the RF window is carried out using Gyrotron Design Suite Version 4.0 (GDSv4.0 2016).
The materiality of the representation of the owl in the Mari ways of speaking
Authors: Yuzieva Kristina
Published: May 2021

This article shows how language materiality is conceptualized through an ethnolinguistic analysis of the representation of the owl as an indication of human-bird relationships. This approach enables addressing the multiple relations between birds and speakers and their perception of the environment as these are reflected in language, folklore and rituals. This research is related to such discourses as “language”, “materiality” and “environment” and is based on a case study of the Mari, a Finno-Ugric people who live in central Russia and still adhere to their folk religion. First, it sets out the Mari names which are used for birds of the owl family, then it shows how the terminology has changed due to the emotional side of humanity, and how terms express things in metaphorical way. Next, the article focuses on how the bird (owl) can be a source of positive or negative information with regard to auguring the future and how the symbolic use of birds in rituals and magical actions contributes to co-creating landscapes between human and non-human agencies. This study is based on extensive linguistic, folklore and ethnographic material, including my own field material.
Zwischen Seelgerät und Standesrepräsentation – das Hôtel-Dieu Beaune
Authors: Zeilhofer Susanne
Published: May 2021

Das Hôtel-Dieu in Beaune ist ein Musterbeispiel für eine Synthese aus spätmittelalterlicher Krankenfürsorge, Glaube und Spiritualität und weltlichen Stifterinteressen. Der Krankensaal, die berühmte salle des pauvres, ist per se spiritueller Raum, bildet in Architektur und Bildwerken den religiös philosophischen Kosmos der Patienten ab und gibt Anleitungen zur Selbstreflexion. Bemerkenswert ist wie Krankenzimmer und Raum der Spiritualität zur Deckung gebracht werden.
From flax fibers to activated carbon electrodes: The role of fiber refining
Authors: Li Hongwei , Feng Yucheng , Tang Lvqiao , Yang Fei
Published: May 2021

Flax-based activated porous carbon materials (APCs) were prepared via KOH and urea synergistic activation in the carbonization process using flax pulp as a biocompatible and eco-friendly biomass precursor. A refining process was used to pretreat the flax pulp fibers, which has been known to improve and optimize the performance of APCs. The morphological and physicochemical structures of APCs were investigated, and the results showed that APCs exhibited high specific surface area and porous microstructure. Furthermore, APCs were rationally designed as a sustainable electrode material. The APC prepared by 60 °SR (Shopper-Riegler beating degree) flax pulp, named APC-60, exhibited the highest specific capacitance of 265.8 F/g at a current density of 0.5 A/g. The specific capacitance retention at 59% remained for the APC-60 electrodes at a high current density of 10 A/g. These results suggested that the flax-based APCs could be a promising carbon-based electrode material for sustainable electrochemical energy storage.
Innovation of delivery of pregnant women with abnormally invasive placenta: placenta percreta (Case of practice)
Authors:   Shupyk National Medical Academy of Postgraduate Education, Kуiv, Ukraine, Golyanovskiy O.V. , Mekhedko V.V. ,   Shupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine, Goncharenko D.O. ,   Kyiv Oblast Center for Maternal and Child Health, Ukraine, Kucher V.M. ,   Kyiv Regional Hospital, Ukraine, Vereshchagin S.V. ,   Kyiv Regional Hospital, Ukraine, Gerasimov S.V. ,   Kyiv Regional Hospital, Ukraine
Published: May 2021

The article presents a case from practice with prenatal diagnostics of abnormally invasive placenta (Рl. Percreta) with invasion into the back wall of the bladder on the background of full placenta previa and previous caesarean section. Stressed the relevance of modern diagnostic pathologists placentation using ultrasound, Doppler and MRI to determine the depth of invasion of the placental tissue into the myometrium is emphasized. An innovative algorithm for delivery of a pregnant woman with this severe pathology using the endovascular technique of temporary balloon occlusion of the abdominal aorta, performing a cesarean section with a subsequent hysterectomy without appendages, ligating of the internal iliac arteries (IIAL), and argon-plasma tissue coagulation is proposed. The proposed method significantly reduces the amount of blood loss, the likelihood of developing massive bleeding, coagulopathic disorders and possible damage to adjacent organs. Key words: abnormally invasive placenta, placenta increta/rercreta, placenta previa, massive obstetric hemorrhage, balloon occlusion of the aorta, argon-plasma tissue coagulation.
Managing biotopes of women – new approaches
Authors:   Shupyk National Medical Academy of Postgraduate Education, Kуiv, Ukraine, Zhuk S.I. , Shluakhtina A.A. ,   Shupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine
Published: May 2021

The objective: the study of the microbiocenosis of the vagina and intestines in pregnant women. Materials and methods. The study included 154 pregnant women. Evaluation of the state of microcenosis of the birth canal in pregnant women was performed in the period of 38 weeks. Results.A microscopic and bacteriological study of fecal and vaginal microflora was performed to assess the degree of disturbance of vaginal and intestinal microbiocenosis in 154 pregnant women at a gestational age of 38 weeks. As a result of microbiological and bacteriological screening, it was found that the majority of the examined pregnant women had various dysbiotic disorders. Conclusion. Consequently, given the presence of a reliable connection between the complicated pregnancy and dysbiotic disorders in the vagina and intestine, it is necessary to more standardize microbiological and bacteriological examination of the vaginal and intestinal microflora. This will enable the timely and correct appointment of both treatment and preventive measures that will help prevent possible complications and thereby reduce perinatal morbidity and mortality. Key words: pregnancy, microbiocenosis, dysbacteriosis of the vagina, intestines, bacterial vaginosis.
Clinical-anamnestical features hyperplastic processes an endometrium at women of genesial age
Authors:   Shupyk National Medical Academy of Postgraduate Education, Kуiv, Ukraine, Sadigov Yu.M.
Published: May 2021

The objective: studying of clinical-anamnestic features the hyperplastic processes an endometrium at women of genesial age. Materials and methods. Clinical examination of 176 women with various options of hyperplastic processes an endometrium (the main group) and 30 women of similar age without gynecologic pathology was conducted. Among women of the main group glandular hyperplasia the endometriya met at 58 (33.0%) patients; polyps an endometrium – at 70 (39.8%) and adenomatous hyperplasia an endometrium – respectively at 48 (27.3%) women. Results. The conducted research taped that for the women suffering from hyperplastic processes an endometrium at genesial age, burdening of the family anamnesis and an adverse background for their development (an idiopathic hypertensia, an obesity, coronary heart disease) are characteristic; an early menarche at glandular hyperplasia an endometrium and polyps an endometrium and later — at an adenomatous hyperplasia an endometrium; the early beginning of sexual life an patients with an adenomatous hyperplasia an endometrium, lack of methods of contraception; professional factors, including hard physical work, influence during the long period time of excess hum, vibration, steams of paintwork materials, production dust; existence of accompanying diseases of the endocrine systems, systems of a circulation, digestive organs; high frequency transferred in the anamnesis and accompanying gynecologic diseases, in features inflammatory diseases of organs of small basin, diseases of mammary glands and hyperplastic processes of cervix uterus. Сonclusion. The received results needs to be considered when developing tactics of maintaining women of genesial age with hyperplastic processes an endometrium. Key words: hyperplastic processes endometrium, genesial age.
Angaben zu der Ausgestaltung und Entwickelung der Urnenfelderkultur in Ungarn
Authors: Kőszegi Frigyes
Published: May 2021

X
Mommsen levelek a Széchenyi Könyvtár kézirattárában (Mommsen-Briefe im Handschriftenarchiv der Széchényi-Bibliothek)
Authors: Kanozsay Margit
Published: May 2021

X
Tug of War over Financial Assistance: Which Way Forward for Eurozone Stability Mechanisms?
Authors: Rehm Moritz
Published: May 2021

This article analyses the development of financial assistance in the Eurozone since 2010. It argues that reforms to instruments and bodies, notably the European Financial Stability Facility, the European Stability Mechanism, and the current Covid-19 recovery fund, are best explained by a re-occurring pattern of negotiations between potential creditors and debtors based on common Eurozone interests and national cost-benefit considerations. Building on a liberal intergovernmentalist approach, this article shows how this pattern influenced the step-by-step reform of financial assistance in the Eurozone. The threat to Eurozone stability served as a constant factor encouraging member states to expand and deepen the assistance formula. Creditors’ cost-benefit considerations were key for retaining disincentives, a limited liability for common debt, and intermediary borrowing and lending within the financing design. However, on the back of common Eurozone interests, debtors were able to push for an increase in assistance, an expansion of assistance into areas of banking sector support, and a softening of moral hazard elements in the more recent Covid-19 pandemic. Due to creditors’ continuous insistence on safeguards and limited burden-sharing, reform outcomes were repeatedly unable to resolve the difficulties at hand.
Актер и педагог Юрий Владимирович Назаров. Штрихи к творческому портрету
Authors: Юркин Вячеслав Александрович
Published: May 2021

Педагогическое мастерство народного артиста России и профессора кафедры искусства Московского гуманитарного университета Юрия Владимировича Назарова вытекает из высокого профессионального уровня актера, его жизненного опыта и взглядов на события текущего времени. В жизни и в профессии мастер прошел большую и интересную школу, которая сформировала его как человека, актера и педагога. Многое в человеке закладывается с детства. Интересен момент выбора профессии и движения к цели.

Изучая биографические материалы и источники, мы видим, что у него было много сомнений в делах и поступках. Особенно это заметно по выбору профессии актера и учебе в театральном училище. Можно сделать вывод, что жизнь закалила и научила Ю. В. Назарова любить свою родину, ценить людей и быть верным призванию.
Development of Algorithms to Identify, Disclose, and Investigate High Tech Crimes of an Extremist Nature Committed Via the Internet
Authors: Bychkov Vasily V. , Prorvich Vladimir A.
Published: May 2021

This article examines the most important problems arising in the detection, disclosure, and investigation of high tech extremist crimes committed through use of the Internet. The main source of legal errors is found through the identification of mandatory and optional signs of crimes of this type according to their deployed criminal legal characteristics, have been revealed. The specific features of seven groups of algorithms are described, on the basis of which proper information support of all kinds of investigative actions can be created. The specifics of this system of algorithms, within an interactive expert framework, allow investigators to receive necessary information support in real time.
The effect of the phytocomplex Renotineх® on postoperative period after external shock wave lithotripsy in patients with urolithiasis
Authors: Neymark Aleksandr I. , Neymark Boris A. , Nozdrachev Nikolay A. , Gatkin Michail Y. , Fursa Yulia S.
Published: May 2021

INTRODUCTION: Phytopreparations are one of the leading medicines used as preoperative preparation and postoperative management in patients with urolithiasis.
THE AIM of the study was to evaluate the nephroprotective effect of Renotinex in patients with urolithiasis after extracorporeal shock wave lithotripsy (ESWL).
MATERIALS AND METHODS: The study included 86 patients (43 in the main and the comparison group) with urolithiasis with localization of the stone in the renal pelvis without disturbing the outflow of urine. All patients underwent extracorporeal shock wave lithotripsy (ESWL). After ESWL patients in both groups received spasmodic, anti-inflammatory, antibacterial therapy. Patients of the main group additionally received Renotinex 2 capsules 3 times a day for 14 days before and 14 days after surgery.
RESULTS: During the observation a more effective discharge of calculus fragments was noted in patients of the main group while taking the phytocomplex Renotinex, as well as less pronounced damage and faster recovery of the renal parenchyma after ESWL according to the level of enzimuria.
CONCLUSION: The results of the study indicate the feasibility of prescribing the phytocomplex Renotinex for nephroprotective and lithokinetic therapy in patients after ESWL.
Patient with urethral pain syndrome: psychological portrait
Authors: Khalak Mariya E. , Molvi Muhammad , Lazukin Valery F. , Bozhkova Elena D. , Streltsova Olga S.
Published: May 2021

The article discusses the psychological characteristics of the patient with chronic pelvic pain syndrome, in particular with its component urethral pain syndrome. The main specific personality traits inherent in such a patient are highlighted; the factors of development of chronic pelvic pain syndrome are determined, including psychological. Doctors were given recommendations for the management of such patients, in particular, the use of psychological scales and questionnaires directed at identifying markers and specific features.
Paul Auster’s postmodern characters: a relativistic/referential dichotomy
Authors: Bolaño Quintero Jesús
Published: May 2021

Paul Auster is one of the most widely studied postmodern authors and his novels have been extensively used as paradigmatic examples of the fiction of this movement. In the light of the recent theoretical debate about the passing of postmodernism, it seems fundamental to explore the way in which Auster conceives the nature of this paradigm, the problems it arises and their possible solutions. The aim of this article is to analyse two recurring types of characters from the Austerian universe that represent two great sources of influence on the novelist: Ludwig Wittgenstein’s philosophy and the ideas from American transcendentalism.
Comparison of tolterodine and Solifancine in treatment of female with overactive bladder
Authors: Hefila Nermeen Mohamed , And el dayem Tamer Mamdouh , Elfazari Hisham Adel
Published: May 2021

Background: OAB (overactive bladder) is primarily a neuromuscular problem in which the detrusor muscle contracts inappropriately during bladder filling (i.e., storage phase). These contractions often occur regardless of the amount of urine in the bladder. The aim of this work is to study the effect of Solifenacin in comparison to Tolterodine in treatment of females with idiopathic over active bladder.Methods: This study included 50 patients who presented between March 2020 and February2021 to the outpatients clinic at El-Shatby maternity Hospital, Alexandria university. The patients were complaining of urinary urgency usually with urinary frequency, nocturia with or without urge incontinence. All cases were divided in two groups one of them receive Solifenacin5mg twice daily and the otherreceiveTolterodine2mg twice daily.Results: Both groups showed significant decrease in frequency number per day with p value <0.001ingroup I with Solifenacin which mean statistically significant difference between two groups. When the percentage of symptoms severity were compared between both groups, group 1 showed 53% reduction in symptoms severity while group II showed 6.67% reduction which cleared significant difference statistically in group I (p=0.001). The percentage of reduction of severity of symptoms was compared between the two groups, it showed about 60%reduction in symptoms severity in group 1while in group II only 9.7% reduction. This was statistically significant with (p<0.001) in group I with Solifenacin.Conclusions: This study suggests that Solifenacin10mg/day is more effective than Tolterodine4mg/day in reducing OAB incontinence episodes.