bluuebunny/crossref_metadata_2025 huggingface dataset:
Comparison of Physicians’ Perceptions Regarding Dermatological Diseases
Authors: AKSOY Hasan , ASLAN KAYIRAN Melek
Published: February 2024

Background/Aims: Physicians frequently encounter skin diseases and provide opinions to their patients regarding dermatology. We aimed to assess the perceptions of physicians regarding skin diseases and to compare dermatologists’ and non-dermatologist physicians’ understanding of specific dermatological issues.
Methods: Through an online form, participants were asked to respond to sentences indicating whether skin diseases are related to the liver or food with options such as "almost always," "mostly," "half-and-half," "less often," and "almost never." Similarly, they were asked to respond to sentences related to avoiding isotretinoin treatment and performing allergy tests in acute urticaria with options as "strongly disagree," "disagree," "partly agree," "agree," and "strongly agree." Statistical analysis was performed using Statistical Package for the Social Sciences v.27.
Results: The sentences “skin diseases are of liver origin” and “skin diseases are caused by foods/drinks” received responses of “almost never” or “less often” at a rate of 91.8% and 80.9%, respectively. The total proportions of participants who selected “strongly agree,” “agree,” or “partly agree” were 53.9% for the statement restricting isotretinoin use and 45.5% for the statement recommending allergy testing in acute urticaria. While 91.8% of dermatologists disagreed with the statement limiting isotretinoin use, 68.3% of non-dermatologist physicians partially or completely agreed. For the statement recommending allergy testing in acute urticaria, 85.8% of dermatologists disagreed, while 55.7% of non-dermatologist physicians partially or completely agreed.
Conclusions: The popular belief that skin diseases are caused by the liver or food has no basis among physicians. However, contrary to the literature, non-dermatologist physicians have expressed opinions that isotretinoin should be used as little as possible due to potential harm to the liver and that allergy tests should be performed in cases of acute urticaria. Giving importance to these topics during medical education will contribute to changing physicians' perspectives and ultimately benefit public health.
Examining the Seroprevalance and Antiviral Prophylaxis Rate of Hepatitis B and C Virus in Rheumatic Patients Treated with Biological and Targeted Synthetic Disease Modifying Anti-rheumatic Drugs: Results from a Tertiary Center in Central Anatolia
Authors: KAPLAN Hüseyin , CENGİZ Gizem , ŞAŞ Senem , KARA Hasan
Published: February 2024

Objective: To evaluate the epidemiological characteristics of hepatitis B virus (HBV) and hepatitis C virus (HCV) in rheumatic patients treated with biological and targeted synthetic disease modifying anti-rheumatic drugs (DMARDs).
Methods: This cross-sectional study was carried out between September 2021 and April 2022 at the Rheumatology Outpatient Clinic of Erciyes University Faculty of Medicine, and it included 200 patients [113 with axial spondyloarthritis (axSpA), 18 with psoriatic arthritis (PsA) and 69 with rheumatoid arthritis (RA)]. The demographic and clinical characteristics, treatment details and viral hepatitis serology of the patients were recorded. Those not receiving biological and/or targeted synthetic DMARDs (b/tsDMARDs) were excluded.
Results: The median age of the patients was 47 (39-58) years, and the median disease duration was 10 (7-15) years. 117 (58.5%) of the patients were female, and 83 (41.5%) were male. The median duration of treatment with b/tsDMARDs was 6 (2-9) years. In the viral serological examinations, 1.5% of the patients were positive for HBsAg, 64.5% for anti-HBs, 23.5% for anti-HBc IgG, and 0.5% for anti-HCV. The anti-HBc IgG positivity rate was significantly higher in RA (34.8%) than axSpA patients (16.8%) and was similar to PsA patients (22.2%) (p = 0.023). Yet HBsAg, anti-HBs, and anti-HCV serologies were similar across patient subgroups (p > 0.05). A total of 44 (22%) patients were undergoing oral antiviral prophylaxis. Three (1.5%) patients who were anti-HBc positive and HBV DNA negative were followed without antiviral treatment. There was no viral reactivation in any patient.
Conclusion: Approximately one in four patients in our cohort showed anti-Hbc positivity, and almost all of them were using antiviral prophylaxis. Anti-HCV prevalence was much lower. Studies addressing viral hepatitis in rheumatic patients and/or patient subgroups, both at the national and local level, will enable rheumatologists to be more effective in managing HBV and HCV.
The Incidence and Risk Factors for the Presence of Type 1B or Type 3 Utero-ovarian Anastomoses During Uterine Artery Embolization
Authors: ÇAY Ferdi , ELDEM Fatma Gonca , ÇİL Barbaros Erhan , PEYNİRCİOĞLU Bora
Published: February 2024

Background/Aims: Demonstration of possible utero-ovarian anastomoses (UOA) before or during uterine artery embolization (UAE) is important to preserve ovarian reserve. This study aimed to evaluate the incidence and risk factors for the presence of type 1b or type 3 UOA in patients undergoing UAE for the treatment of uterine myomas.
Methods: Procedural angiographies of patients who underwent UAE were evaluated in a single academic center. Patients’ demographics, indication for UAE, presence and type of UOA, presence of adnexal pathology at preprocedural MRI, history of pelvic surgery, and total uterine volume at preprocedural MRI were retrospectively evaluated. Analysis of the aforementioned variables between patients with and without UOA was performed.
Results: This study included 30 patients with a mean age of 41.97±5.72 years (range 32 - 56). UOA was found in 17 (56.6%) patients, 10 (33.3%) of them were type 1b, and 7 (23.3%) of them were type 3. Five patients (17.2%) had adnexal pathology at pre-procedural MRI and 12 patients (40%) had a history of pelvic surgery. The mean total uterine volume was 607.1 cm3. In the analysis of variables between patients with and without UOA, UOA presence was significantly higher in patients with a history of pelvic surgery (p=0.005). All of the patients with a history of myomectomy were found to have type 1b or type 3 UOA. No significant relation between UOA and age, the presence of adnexal pathology, and uterine volume were detected.
Conclusion: Utero-ovarian anastomoses are commonly encountered during UAE. A history of pelvic surgery was found to be a risk factor for the presence of type 1b and type 3 UOA.
The Relationship Between Type D Personality, Bedtime Procrastination and Sleep Quality
Authors: UYGUR Hilal , DEMİRÖZ Dudu , UYGUR Ömer Faruk , DUMAN Ayse
Published: February 2024

Background/Aims: Bedtime procrastination (BP) is an unhealthy sleep behavior, but its relationship with Type D (distress) personality has never been examined. This study aimed to investigate the relationship between Type D Personality, BP, and Sleep Quality in university students.

Methods: In this cross-sectional study, we applied the sociodemographic sleep data form, Type D personality scale (DS-14), Bedtime Procrastination Scale (BPS), Pittsburgh Sleep Quality Index (PSQI) (subjective sleep quality and daytime dysfunction subscales), Insomnia Severity Index (ISI), and Epworth Sleepiness Scale (ESS). All participants were divided into two groups: Type D personality and non- Type D personality. Sleep variables and scales were compared between these two groups. Additionally, correlation analysis was performed between the scales and the subdimensions of Type D personality.

Results: We completed our study with 209 university students (66%, n = 138 female and 34%, n=71 male). The mean age was 22.17 ± 4.33, and 51.2% of all participants had Type D personality. Sleep quality was poor, and insomnia was more severe in participants with Type D personality. Participants with Type D personality had more delayed bedtime. Negative affectivity was associated with poor sleep quality, more severe insomnia, and BP, but social inhibition was not associated with BP.

Conclusion: Clinicians should consider the negative affectivity sub-dimension of Type D personality contributing to BP behavior among university students when planning interventions to reduce BP behavior.
Dosimetric Comparison of Inverse Planning Simulated Annealing and Manual Optimization for Intracavitary Cervix Brachytherapy
Authors: GÜL Osman Vefa , BAŞARAN Hamit , DUZOVA Mursel , İNAN Gökçen
Published: February 2024

Background/Aims: Different optimization methods in brachytherapy treatment planning is used. The aim of this study is to evaluate dosimetric differences between manual optimization (MO) and inverse planning simulated annealing (IPSA) planning techniques commonly used in brachytherapy of cervical cancer.
Methods: Fifteen cervical cancer patients were included in this study. Nucletron standard tandem-ovoid (TO) applicators were used for treatment. High-risk clinical tumor volume (HR-CTV), bladder, rectum, and sigmoid contouring were performed according to GEC-ESTRO recommendations. Two plans were created for each patient using IPSA and MO techniques. While a dose of 700 cGy was prescribed to the target volume during the planning phase, an effort was made to protect the organs at risk in the best way possible. IPSA and MO planning techniques were compared via dose volume histogram (DVH).
Results: There was no significant difference between HR-CTV and CI values for MO and IPSA techniques. There was a significant difference between IPSA and MO techniques for the 2cm3 volume of the rectum (p= 0.002). It was observed that the bladder was better protected by the IPSA technique. There was a 6.26% dose difference between IPSA and MO for the bladder. A significant difference was found between IPSA and MO techniques for the 2cm3 volume of the sigmoid (p= 0.002). The IPSA technique was superior to the MO technique in terms of time.
Conclusions: The IPSA technique was superior to the MO technique in terms of protecting organs at risk (OARs). IPSA provides a faster and higher quality plan in cervical brachytherapy.
Assessment of the Opinions of Anesthesiology and Reanimation Research Assistants Regarding Clinical Anatomy Education: A University Example
Authors: ASLANLAR Emine , KARA İnci , ÜNVER DOĞAN Nadire , FAZLIOĞULLARI Zeliha , BÜYÜKCAVLAK Mustafa
Published: February 2024

Introduction: Anatomy is considered one of the cornerstones of medical education. In-depth understanding of anatomy is essential, especially for safe clinical practice in surgical disciplines. This study aimed to evaluate the feedback of research assistants in the department of anesthesiology and reanimation, who received clinical anatomy education.

Methods: Clinical anatomy education was provided for research assistants at different levels in the department of anesthesiology and reanimation, with two hours per week, and the education was completed within one month. The 5-point Likert scale questionnaire consisting of 18 questions was administered to research assistants to gather their opinions about education. Participants were asked to rate the questions on a scale from 1 to 5. Additionally, data such as age, gender, duration of clinical experience, experience with neuroaxial or peripheral nerve blocks, and participation in regional anesthesia courses were recorded.

Results: A total of 40 participants, including 15 (37.5%) males and 25 (62.5%) females, with an average age of 29.67 ± 3.94 years, were included in the study. Nearly all participants in our study reported that integrated clinical anatomy education is necessary. The majority mentioned that anatomy education would contribute to airway management and regional anesthesia applications. The participation rate in regional anesthesia courses before education was 17.5%. There was no significant difference in average questionnaire scores between those who participated in regional anesthesia courses and those who did not (p=0.06).

Conclusion: In the process of anesthesiology and reanimation specialization training, we believe that incorporating clinical anatomy education would enhance the quality of specialization education, thereby improving safety and effectiveness in clinical applications.
Is Less Surgical Treatment Possible in the Treatment of Degenerative Spine Diseases? Four-Year Follow-up Results of Foraminal Epidural and Facet Joint Injection Treatments
Authors: ERTEM Uğur
Published: February 2024

In this article, I would like to share my opinions about the article named 'Is Less Surgical Treatment Possible in the Treatment of Degenerative Spine Diseases? Four-Year Follow-up Results of Foraminal Epidural and Facet Joint Injection Treatments' (1). First of all, I would like to thank the authors. I will especially try to contribute to this article from the perspective of a physical medicine and rehabilitation physician.
Gastroplastia endoscópica como alternativa à cirurgia bariátrica: uma revisão abrangente de literatura
Authors: Linhares Mateus Rodrigues , Caetano Maria Clara de Paula , De Oliveira Gabriella Mendonça Leão , Nasser Ahmad Abdallah Hilal , Hilal Jalal Basel Jalal , Matos Pedro Lucas Pereira , Jaime Helen Machado , Santana Diego Ferreira , Andrade Michelly Sayuri , Borsio Maria Ligia Teles , Freitas Luiza Firveda , Ugrinovich Carolina Santos , Andreoti Mariana Mercadante , Messac Camila Alves , Farias Renato de Freitas , Costa Walker Stefany Cordeiro , Gasparoni Jamyli Assef Nunes Poggiali , Gasparoni Márcio Thadeu Assef Nunes Poggiali
Published: February 2024

O número de indivíduos obesos está aumentando continuamente, tornando a obesidade um sério problema de saúde pública no presente e no futuro. Dessa maneira, a cirurgia bariátrica oferece uma solução eficaz para muitos pacientes, mas os recursos não são suficientes para conduzir programas cirúrgicos em toda a população. Além disso, a cirurgia não é reversível, tem riscos processuais imanentes, nem todos os pacientes estão dispostos e, para alguns deles, pode ser um tratamento excessivo. Por conseguinte, vários procedimentos endoscópicos surgiram para fechar a lacuna entre a terapia conservadora e a cirurgia bariátrica, ganhando aceitação como mais eficaz do que medidas de dieta e estilo de vida e menos invasiva do que a cirurgia bariátrica. Dessa forma, com o crescente corpo de literatura sobre a gastroplastia endoscópica como uma alternativa a realização de cirurgia bariátrica, foi possível a realização de uma revisão integrativa de literatura por meio da plataforma pubmed, com seleção e análise criteriosa dos artigos, a fim de revisar e analisar as evidências atuais sobre a gastroplastia endoscópica, cirurgia bariátrica e as vantagens de uma em relação a outra. Nesta revisão foi identificado que a gastroplastia endoscópica se caracteriza como uma opção intermediária para o tratamento da obesidade, não tão conservadora quanto os tratamentos farmacológicos e de modificações do estilo de vida, nem tão radical quanto às cirurgias bariátricas. Essa técnica apresenta uma incidência muito menor de complicações, antes, durante e após o procedimento, e quando presente é de fácil controle, melhorando apenas com o tratamento sintomático. Ademais, observou-se uma diminuição na taxa de complicações e no tempo total do procedimento com o progresso dos estudos individuais, sugerindo uma curva de aprendizado associada à técnica. Entretanto, até agora, a experiência com as técnicas endoscópicas é pequena, mas promissora, pois a baixa taxa de complicações com eficácia clínica comparável em alcançar e manter a perda de peso desejada torna-o uma opção atraente a ser considerada entre outras terapias bariátricas. Portanto, o manejo do ganho de peso após cirurgia bariátrica primária é interessante ser feito de tratamento médico e/ou revisão endoscópica, que requer uma abordagem multidisciplinar, na qual oferece diversas opções de tratamento, desde abordagens menos invasivas até técnicas de sutura endoscópica de espessura total.
A Síndrome de Dumping e sua relação com a cirurgia bariátrica: uma revisão de literatura
Authors: Linhares Mateus Rodrigues , Caetano Maria Clara de Paula , Naser Dúnia Shadi Riad Hilal , Hilal Jalal Basel Jalal , Lopes Laura Toledo , Matos Pedro Lucas Pereira , Santana Diego Ferreira , Soares Isabella Nepomuceno , Bez Julia Triaca , Farias Renato de Freitas , Costa Walker Stefany Cordeiro , Braga Andressa Brandão do Couto , Decanini Michel Ifko , De Oliveira Fernanda , Urzedo Gabriel Osaki Queiroz , Pimentel Petra Nickole Noronha de Brito , De Araujo Maria Julia Gama Winther
Published: February 2024

A obesidade é uma epidemia global e um dos principais problemas de saúde nos Estados Unidos e em todo o mundo. Assim, a cirurgia bariátrica (CB) é hoje a terapia mais eficaz para induzir perda de peso a longo prazo e para reduzir a carga de comorbidades e mortalidade em pacientes com obesidade grave, tendo sido recomendada pelas diretrizes atuais de obesidade de acordo com os níveis do índice de massa corporal (IMC) e doenças associadas à obesidade. Contudo, foi observado que qualquer cirurgia de grande porte, incluindo a cirurgia bariátrica, envolve o potencial de complicações, e os médicos precisam estar preparados para reconhecer tais complicações após a cirurgia. Uma complicação que tem se tornado cada vez mais reconhecida em pacientes pós-cirurgia bariátrica é o desenvolvimento de síndrome de dumping (SD), que devido a alteração da anatomia e inervação gastrointestinal, permite que uma quantidade considerável de alimentos não digeridos chegue ao intestino delgado demasiado rapidamente, causando a sintomatologia típica dessa síndrome. Dessa forma, com o crescente corpo de literatura sobre a síndrome de dumping e sua relação com a realização de cirurgia bariátrica, foi possível a realização de uma revisão integrativa de literatura por meio da plataforma pubmed, com seleção e análise criteriosa dos artigos, a fim de revisar e analisar as evidências atuais sobre o impacto da cirurgia bariátrica nos paciente, como o desenvolvimento da SD. Nesta revisão foi identificado que Síndrome de Dumping é uma complicação prevalente, mas provavelmente pouco reconhecida, da cirurgia esofágica e gástrica, incluindo intervenções bariátricas. Atualmente, não existem diretrizes estabelecidas sobre o seu diagnóstico e tratamento, dessa forma, pacientes e profissionais de saúde podem se beneficiar sabendo que, embora o autorrelato de efeitos colaterais gastrointestinais seja relativamente comum, episódios de dumping, vômito e plenitude gástrica são relativamente raros durante os primeiros 6 meses após as cirurgias bariátricas. Portanto, a ideia de que a SD induz mudanças na preferência alimentar é improvável, pois a maioria dos pacientes com dumping grave ainda relata que aprenderam a consumir apenas pequenas quantidades que não causam sintomas viscerais negativos ou a consumir doces à noite, antes de dormir, evitando assim, a sintomatologia dessa síndrome. Logo, o dumping pode ser considerado uma sequela positiva e não uma complicação.
A relação entre a terapia hormonal e o surgimento do câncer de mama: uma análise de literatura
Authors: Caetano Maria Clara de Paula , Naser Dúnia Shadi Riad Hilal , De Oliveira Gabriella Mendonça Leão , Santana Diego Ferreira , Nasser Ahmad Abdallah Hilal , Jaime Helen Machado , Andrade Michelly Sayuri , Barboza Luara Couto , Marques Maria Júlia Cardoso , Borsio Maria Ligia Teles , Freitas Luiza Firveda , Ugrinovich Carolina Santos , Andreoti Mariana Mercadante , Messac Camila Alves , Fernandes Brendha Campos , Soares Isabella Nepomuceno , Marques Ingrid Barabach , Costa Eduarda Emilly Silva
Published: February 2024

A longevidade está aumentando em todo o mundo para as mulheres, e até 2050 são projetadas 1,6 bilhão de mulheres com 50 anos ou mais. A privação de estrogênio após o status da menopausa pode impactar vários aspectos da saúde e qualidade de vida, determinando sintomas vasomotores (VMS), síndrome genitourinária da menopausa (GSM), disfunção cognitiva, distúrbios do sono e alterações no metabolismo ósseo. A terapia de reposição hormonal (TRH) continua sendo o tratamento mais eficaz para esses sintomas, e demonstrou prevenir perda e fratura óssea. Porém, há ainda uma questão não respondida sobre a incidência e o desenvolvimento do câncer de mama, que pode até levar à morte, estão correlacionados com o uso sistemático da terapia hormonal com estrogênio ou o uso de terapia combinada de estrogênio e progestágenos durante a menopausa. Dessa forma, com o crescente corpo de literatura sobre a relação entre a terapia hormonal e o surgimento do câncer de mama, foi possível a realização de uma revisão integrativa de literatura por meio da plataforma pubmed, com seleção e análise criteriosa dos artigos, a fim de revisar e analisar as evidências atuais sobre o a relação entre TRH e o câncer de mama. Nesta revisão foi identificado que o CA de mama é causado por uma interação complexa de fatores modificáveis, não modificáveis e desconhecidos, dentre eles a TRH e suas característica como: idade de início e duração da reposição, a escolha da monoterapia ou terapia combinada, indicação e contraindicação para tal. Em relação a terapia hotmail, o risco foi diretamente proporcional à duração do uso e a escolha do hormônio utilizado, aumentando à medida que a idade da mulher aumenta, e a administração da terapia hormonal deve ser feita até os 59 anos de idade ou nos primeiros dez anos da menopausa. Portanto, conclui-se que o câncer de mama é causado por uma interação complexa de vários fatores modificáveis e não modificáveis e de modo geral, a terapia hormonal combinada foi associada a um risco aumentado de câncer de mama, porém existem vários dados complexos que precisam ser interpretados.
Estimativa da resistência à tração perpendicular em função da resistência ao cisalhamento paralelo às fibras de madeiras de florestas nativas
Authors: Ferreira Tobias Ribeiro , Menezes Isabella Silva , De Morais César Augusto Galvão , Bertolini Marília da Silva , De Campos Cristiane Inácio , Lahr Francisco Antonio Rocco , Christoforo André Luis
Published: February 2024

A existência humana depende especialmente da exploração dos recursos disponíveis no planeta. Com o aumento da população mundial, torna-se necessária a utilização de materiais renováveis, com baixa emissão de poluentes, duráveis e que demandem o mínimo de energia para sua produção. Nesse contexto, a madeira é apresentada como uma solução muito adequada. Considerando o uso da madeira como material estrutural, o conhecimento das suas propriedades e comportamentos diante das mais diversas solicitações é fundamental para que o dimensionamento da edificação proporcione segurança, economia e bom desempenho em sua utilização. Em virtude da anisotropia, própria da madeira, uma série de propriedades são requeridas para que o material possa ser caracterizado. A exemplo disso a ABNT NBR 7190-3 (2022) estabelece que para a caracterização completa da madeira serrada, sejam realizados ensaios que estimem onze propriedades distintas. Realizar todos os ensaios pode ser um grande desafio em virtude da indisponibilidade de materiais, equipamentos e pessoal treinado para realização dos procedimentos normativos. Em situações nas quais, se utiliza madeira de florestas nativas e os ensaios são feitos em corpos de prova, é possível estimar o valor de um parâmetro a partir de outro já conhecido, a ABNT NBR 7190:2022 apresenta diversas dessas relações. Esse artigo traz a proposta de estabelecer uma equação que relaciona as resistências entre o cisalhamento paralelo às fibras (fv0,k) e a tração perpendicular às fibras (ft90,k), que ainda não foi proposta pela norma.  Para propor a equação foi utilizado o método dos mínimos quadrados e para avaliar sua precisão utilizou-se análise estatística. A  principal conclusão do trabalho foi estabelecer a relação ft90,k / fv0,k = 0,24 a ser sugerida para a próxima revisão da norma.
Equivalence-based instruction and the teaching of statistics: a systematic literature review
Authors: De Oliveira Júnior Ailton Paulo , De Carvalho Diego Marques , Benitez Priscila , De Souza Natália Galvão Simão , Barbosa Nilceia Datori , Santos Luzia Roseli da Silva , Silva Luciene dos Santos
Published: February 2024

In this work, the objective was to systematically analyze the literature found in the world context that addressed the use of Equivalence-Based Instruction (EBI) in teaching statistical concepts at any level of education. Seventeen works were selected and the IRaMuTeQ software was used to carry out multivariate textual analysis by organizing texts that were prepared considering the focus of the research, the method used, the context in which the work was developed, the type of study and the main results and conclusions. The analysis showed the potential of using the EBI for teaching advanced concepts in Statistics (statistical inference) to higher education students. In addition, the research showed a large space to be filled by research that explores the use of teaching technologies derived from IBE associated with experimental applications aimed at teaching statistics in the context of basic education.
Saúde mental dos profissionais da saúde durante a pandemia da Covid-19
Authors: Pereira Hugo Juliani de Oliveira , Farias Estrela Cecília Moreira de Holanda , De Araújo Gabriel Rocha Pinon Teixeira , De Araújo Alex Duarte , Da Silva Thiago Martins , E Vasconcelos Cícera Andressa Lopes , Mendes Marcela Carvalho , Coelho Gerson Maciel , Apolinário Joelma Maria dos Santos da Silva , Rozendo Jefferson Florencio
Published: February 2024

A pandemia da COVID-19 impôs desafios significativos à saúde mental dos profissionais da saúde, destacando a necessidade de uma investigação abrangente sobre os impactos psicológicos associados a essa crise global. Esta revisão integrativa tem como objetivo analisar e sintetizar as evidências disponíveis na literatura sobre os efeitos na saúde mental dos profissionais da saúde durante a pandemia da COVID-19, identificando fatores de risco, estratégias de enfrentamento e lacunas de pesquisa. Utilizando uma abordagem de revisão integrativa da literatura, foram examinados estudos publicados no período pandêmico em diversas bases de dados, incluindo PubMed, Scopus e PsycINFO. A seleção dos estudos seguiu critérios específicos de inclusão e exclusão, garantindo a qualidade e relevância das informações analisadas. A análise dos estudos revelou uma ampla gama de impactos na saúde mental dos profissionais da saúde, incluindo aumento do estresse, ansiedade, depressão e exaustão emocional. Fatores como carga de trabalho intensificada, falta de recursos adequados e preocupações com a própria saúde foram consistentemente associados a esses desafios. Além disso, estratégias de suporte psicológico e intervenções foram identificadas como essenciais para mitigar os efeitos negativos. Os resultados destacam a urgência de implementar medidas de apoio à saúde mental dos profissionais da saúde, reconhecendo a importância de intervenções específicas e de políticas institucionais voltadas para o bem-estar desses profissionais. A pesquisa futura deve se concentrar em abordagens inovadoras e personalizadas para fortalecer a resiliência e promover a saúde mental durante crises semelhantes.
Revisão sistemática de literatura utilizando o software StArt – delimitação em artigos na temática de ligações em estrutura de madeira e materiais compósitos no período de 2011 a 2023
Authors: Penteado Lucas Dellosso , Dos Santos Herisson Ferreira , Moura Jorge Daniel de Melo , Branco Luiz Antônio Melgaço Nunes , Chahud Eduardo , Lahr Francisco Antonio Rocco , Christoforo André Luis
Published: February 2024

O uso de estruturas de madeira é amplamente difundido em países localizados no Hemisfério Norte. A grande utilização da madeira é justificada por apresentar alta relação resistência e peso, baixo consumo de energia e confiabilidade em aplicações estruturais. No Brasil, apesar da extensa quantidade de espécies no território o uso se restringe em estruturas treliçadas de telhados. No entanto, a combinação da madeira com as tecnologias atuais permite a utilização desse material em estruturas de grandes dimensões. Grandes estruturas, em altura e/ou em vão, requerem elementos estruturais com grandes seções transversais e conexões entre os elementos. Portanto, as conexões se tornaram um importante e usual elemento nessas estruturas. Com o objetivo de melhorar o comportamento estrutural das peças de madeira, diversas pesquisas utilizam materiais compósitos reforçados com fibras, sendo os principais: Fibra de vidro (GFRP) e Fibra de Carbono (CFRP). A utilização desses materiais provoca o aumento de resistência dos componentes estruturais. Esses materiais utilizados para reforços são disponibilizados em formatos e tamanhos diversos, como: lâminas, tecidos, chapas e barras. Este artigo tem como finalidade apresentar uma Revisão Sistemática de Literatura (RSL), produzida nos últimos anos, com pesquisas relacionadas às áreas de ligações em estruturas de madeira e o uso de materiais compósitos. As pesquisas por trabalhos nesta temática compreenderam literatura internacional, considerando os anos de 2010 a 2023. O processo de RSL foi realizado com o auxílio do software StArt. Após a realização da RSL verificou que as conexões são os pontos que apresentam a maiores condições para colapso da estrutura, grande parte das pesquisas analisam o comportamento mecânico de ligações utilizando se simulação numérica. O uso de materiais compósitos se destaca como reforços de estruturas, sendo pouco utilizado como reforço nas conexões.
“Pantera Negra é do bem?” dispositivos afirmativos da cultura africana e afro-brasileira em uma experiência escolar
Authors: Kehler Gabriel dos Santos , Silva Juniele Martins , Ceretta Patricio , Peixoto Priscila dos Santos
Published: February 2024

Este artigo apresenta reflexões sobre o debate da Cultura Africana e Afro-brasileira em registros pedagógicos de um projeto interdisciplinar desenvolvido em uma Escola Municipal de Itaara-RS (ano letivo de 2018). Os conceitos de biopolítica e necropolítica foram mobilizados teórico/metodologicamente na e para a captura de dispositivos afirmativos dos corpos-negros, com efeitos à problematização sobre a importância da temática nas escolas e sua urgência em visibilidades de referenciais positivos. Em suma, os registros pedagógicos provocaram a desnaturalização de preconceitos e intolerâncias históricas, culturais e sociais, culminando com sua exposição na Semana da Consciência Negra da escola, sendo que todo projeto foi pensado e desenvolvido baseado no conceito de biopolítica de Foucault (1985), observando como as políticas afirmativas operam nesse sentido e pelo conceito de Necropolítica de Mbembe (2016), mostrando como os povos e a cultura africana sofrem um processo sistemático de extermínio físico e simbólico. Entre as atividades desenvolvidas, podemos citar: confecção de bonecas abayomy, confecção de máscaras africanas, debates sobre racismo, trabalhos sobre a mitologia dos orixás, exposição culinária e um ciclo de cinema com filmes que abordam a temática; Entre essas ações, a última contribuiu para o título desse artigo por meio da exibição do filme “Pantera Negra” (2018), da Marvel. Durante a exibição, uma estudante branca, assistia com desconfiança ao filme e passados alguns minutos ela indagou a professora: – “Professora, o Pantera Negra é do bem?” A expressão e desconfiança da estudante ao assistir um filme que trata a cultura africana de forma emponderada e coloca um jovem negro como super-herói produziu certo “desconforto”, uma vez que é recorrente presença de atores e atrizes negras na televisão e cinema em papeis que remetem à escravidão, corpos-negros em subserviência e ao posto de grandes vilões. Ademais, enquanto trabalho contínuo e interdisciplinar fica a aposta no deslocamento de um corpo que foi marcado e nomeado pelas credenciais do aprisionamento, para uma enunciação afirmativa de pertencimento: Sim, o Pantera Negra também pode ser do bem! Afinal, o que pode(m) e/o não pode(m) um/vários corpo(s)-negro(s)?
FACTORS CONTRIBUTING TO HIGH RATES OF CEASERIAN SECTION
Authors: KHOSO Z , MEMON KN , CHANNAR HB , BHUTTO Z , PARVEEN R , SALAM MU , BAQAR M
Published: February 2024

The increasing rate of caesarean deliveries is a major concern for public health experts worldwide. A study was conducted from January to September 2022 at the civil hospital Khairpur Mir to determine the rates of C-sections compared to normal vaginal deliveries and to evaluate the factors contributing to their increased rate in women. The study included 354 pregnant women aged 20 to 40 years who were surveyed using a pre-tested, structured questionnaire. The data was then analysed using SPSS version 16. Out of the 354 participants, 129 (36.4%) were aged between 31 to 35 years, 211 (59.6%) were uneducated, and 174 (49.2%) belonged to the middle socio-economic status. Furthermore, 103 (42.9%) women delivered by C-section, while 71 (62.3%) had a normal delivery. 54 (15.3%) participants had a parity of three, of which 19 (7.9%) women delivered by C-section, and 35 (30.7%) delivered by normal vaginal delivery. The study found that factors such as maternal age, mother's education, pregnancy complications, utilization of antenatal care, place of birth, area of residence, wealth profiles of mothers, and the number of exercises performed in the last semester were all linked to C-section. The study shows that these factors were the major contributors and strongly associated with higher C-section rates than normal deliveries. Additionally, educational status, occupation, economic status parity, place of C-section, place of ANC visit, and number of ANC visits were also found to be linked to C-section. The p-value was found to be 0.05. In conclusion, this study highlights the need for increased awareness and education on the factors contributing to the high rate of C-section deliveries, and the importance of normal vaginal deliveries for the health and well-being of both mother and child.
Comparative Quality Control Assessment of Different Brands of Rasayana Churna Available in Indian Market
Authors: Upadhyay Anjali , Singh Rohit , Yadav Pramod , Prajapati Pradeep
Published: February 2024

Introduction: Quality assessment is imperative to establish safety and effectiveness of a drug. Rasayana Churna (RC) is a classical Ayurvedic formulation indicated in various diseases. Present study has been endeavoured to generate comparative analytical profile of different marketed brands of Rasayana Churna in India.
Material & Methods: Rasayana Churna was prepared as per the method mentioned in Ayurvedic Formulary of India and marketed RC samples of GMP certified pharmacies were procured from local market in New Delhi and coded as Brand A to Brand G. all the samples were evaluated for organoleptic, physicochemical, phytochemical, HPTLC, FTIR, UV spectroscopy and PCA analysis.
Results: All the samples of Rasayana Churna have shown similar organoleptic characteristics but exhibited difference in their pharmaceutical (carr’s index etc.), physicochemical, HPTLC, FTIR, UV-Vis spectroscopy and PCA profiles. Most of the quality parameters values were found in line with previously reported studies but major difference in value of quality parameters has been observed.
Conclusion: The present study revealed inter sample variability in various quality control parameters. In order to limit this variability, quality certification for raw drug and adoption of uniform SOP/SMP should be made essential to ensure the quality of finished product. Apart, in order to achieve greater accuracy in findings, further quality control studies can be initiated involving different marketed samples of a drug manufactured at same point of time.
Spontaneous regression of cancer: a review of cases reported in Indian literature
Authors: Paradkar Prajakta , Vaidya Rama , Shankare Sushma , Khambete Siddhisha , Vaidya Ashok
Published: February 2024

Spontaneous regression of tumors is an exceptional response in the absence of standard treatment for the disease. The associated mechanisms are not completely understood, however immune modulation has been indicated to be the most probable process for spontaneous regression. Summarizing and analyzing the available information of these cases may aid in developing effective and safe therapeutic modalities for cancer. This review investigates the spontaneous regression cases reported in India during the period of 1988 to 2022. We conducted an online search (Google and Pubmed) using the keywords “spontaneous regression, cancer, India” for reports from India. All reports in the relevant literature were investigated for the criteria of spontaneous regression by Everson and Cole. 18 cases were defined as spontaneous regression and are reviewed in this article. The available information regarding patient demography, diagnosis, treatments and follow-up has been summarized. Squamous cell carcinoma is the most common type among 18 cases. 12 cases showed complete regression of tumor whereas 5 of them were partially regressed. Only 4 cases received chemotherapy and rest were not treated with any conventional anticancer treatment. An attempt has been made to delineate the mechanisms for SR proposed by the investigators. Acquiring data of more cases and more detailed information will definitely help us understand the mechanism of regression, providing an opportunity to improve cancer immunotherapy strategies.
Quality evaluation of marketed samples of Danti moola (Baliospermum montanum Muell. Arg. roots)
Authors: Kundra Latika , Kaushik Shreshtha , PV Anandaraman , Dharmarajan Prasanth
Published: February 2024

Background: Baliospermum montanum Muell-Arg, Euphorbiaceae, often known as "Danti," is such an indispensable herbal drug of the Ayurvedic health care system. This herb is marketed under various names such as Danti, Dravanti and Hastidanti.
Objective: Its identification is a subject of confusion and controversy owing to the availability of several different species of this herb on one hand. In apropos of a survey through the market, it was found that the authentic Danti is not offered for sale, and the specimens were discovered to be fragments of other similar drugs. Thus, an attempt has been made to generate a comparative analytical profile of three marketed samples of Dantimoola through physicochemical analysis, pharmaceutical tests, phytochemical evaluation as well as distinct advanced techniques namely, FTIR (Fourier transmission Infrared Spectroscopy) and High- Performance Thin Layer Chromatographic (HPTLC) Assay.
Methods: Samples of Danti moola (root) were procured from easily approachable local herbal drug markets of three different states viz. Delhi, Jaipur, and Maharashtra. These were identified and further authenticated. After that, samples were subjected to various physiochemical and phytochemical tests along with FTIR and HPTLC.
Results: Marked variations have been observed in all the samples while subjected to various analytical tests ranging from the sensory evaluation to sophisticated analysis.
Conclusion Here, an attempt has been made to provide a holistic overview of Danti through various analytical tests conducted in this study, though this is a preliminary one. Nevertheless, in-depth robust studies and the use of chemometrics may be valuable in obtaining more pertinent and supplementary information.
The Management of Post Covid Multisystem Inflammatory Syndrome (MIS) through Āyurveda -A Case Series
Authors: Gujarathi Rahul , Patwardhan Ravindra , Nilakhe Savita
Published: February 2024

The Pandemic of COVID-19, caused by SARS-CoV-2, is a new disease, nothing was known about it including pathogenesis, course of the disease, treatment, complications, or even its sequels. Treatment was mostly symptomatic with daily changing protocols. Many lost their lives either due to the infection or due to complications or post-recovery sequels like mucormycosis or Multisystem Inflammatory Syndrome (MIS). MIS was a related post-recovery sequel, which was not exactly understood in the very early stages. Later when it was confirmed as a complication of COVID-19, treatment protocols were framed, mostly symptomatic. The recovery was painful with varying morbidity and recovery rates. Modern medicine did succeed in framing the diagnostic guidelines but failed in providing a foolproof inclusive treatment protocol. The present case series focuses on the encouraging results obtained through Ayurveda in managing MIS, using cost-effective and commonly used anti-inflammatory medicines which proved to be effective in reducing the symptoms and also the biochemical inflammatory markers.
Proposal of a Personalized Panchakarma (bio-purificatory) treatment Algorithm for Amavata with special reference to Rheumatoid Arthritis
Authors: S Aswathy , M Arun , V Anandaraman , K Prathibha , Dharmarajan Prasanth
Published: February 2024

Personalised care has become an emerging concept in different field of biomedicine, which has already been established in field of Ayurveda from ages. By the concept of Purusham Purusham Veekshya (individualized or personalized medicine), it makes the researchers and physicians to analyse all the factors like Dosha, Dushya, Bala, Kala, Prakriti, Anala, Vaya, Satwa, Satmya, Ahara, Desha and then plan a personalised treatment protocol for every patient of a particular disease. In contrast to the treatment protocols which are being forcefully used especially in the postgraduate and PhD dissertations which is a kind of one-size-fits-all approach, an algorithm development will help in providing customised treatments fit for each individual. The treatment protocols for managing Rheumatoid Arthritis/Amavata are different to each patient when we consider the stage of the disease as well as the predominant Dosha involved. As Ayurveda emphasizes the selection of therapies in a more individualised approach with patients considering Roga Bala (strength of a disease) Rogi Bala (strength of a patient) Vyadhi Avastha (stages of disease), here is an attempt to propose an Ayurveda treatment algorithm for the management of Rheumatoid Arthritis by following the principles from Amavata Chikitsa.
Management of Non-Alcoholic Grade II fatty liver with a single formulation Rohitaka Abhaya kwatha – A case report
Authors: Raj Anju , jyothi Arshath , Yadava Rama
Published: February 2024

NAFLD is fast becoming one of the most common causes of chronic liver disease worldwide and is now a major cause of liver-related morbidity and mortality. It is one of the most common liver diseases, usually occurring due to lipid accumulation, mostly triglycerides in hepatocytes. This is the case report of the successful management of Non-Alcoholic fatty liver disease (NAFLD), managed with a single formulation Rohitaka Abhaya kwatha. A 43-year-old female patient, relatively overweight (BMI = 27) presented with right hypochondriac pain, fatigue, incomplete bowel evacuation, and abdominal heaviness. There was no significant clinical abnormality except a high body mass index on examination. Hematological examinations revealed altered liver function tests. The patient was given Ayurveda treatment for two months. After two months, significant improvement was observed in signs and symptoms and BMI. After that, she was advised to follow the diet for the next three months. Sonography reports reveal no fatty infiltration after five months. The present case highlights the potential of a single formulation in the management of Non-Alcoholic Fatty Liver Grade II.
Evaluation of ovulation effect of shuddha tankana (borax) in letrozole induced polycystic ovarian syndrome an experimental study
Authors: Babali Jyoti , Hadimur Kasinath , Patil Kasturi
Published: February 2024

PCOS is a disorder with alterations in the structure as well as functions of female reproductive organs and is also associated with metabolic disorders. Findings from animal models to reveal the drug pharmacology further it also provides insights into the implications from these studies for improved clinical management of this disorder. In present study PCOS induced by Letrozole and treated with Shodhita tankana (test drug). Tankana on one of the kshara Dravya which possess stree shukra janana property, which may considered as Ovulating property. Hence to revalidate property & to compare its results were compared with standard drug Clomifin citrate (Standard drug). Study was conducted At the end of study wister strain albino rats were scarified Overy & Uterus isolated for histomorphometry changes & blood sample collected to know the hormonal changes.
The test drug Shuddha Tankana has shown a significant result and similar to that of standard drug Clomiphene citrate result in letrozole induced PCOS.
Sinusite maxillaire d’origine dentaire : à propos d’un cas clinique
Authors: ADNANE SALMA , Haitami Sofia , Yahya Ihsane
Published: February 2024

La sinusite maxillaire d’origine dentaire est une réaction inflammatoire de la muqueuse du sinus maxillaire consécutive à une infection d’origine dentaire.
C’est une forme étiologique fréquente des sinusites maxillaires, et se caractérise par l’unilatéralité des signes cliniques et radiologiques.
Une source odontogène doit être suspectée chez les patients rapportant à l’ anamnèse de douleur, d’infection dentaire ou de soins dentaires récents et qui présentent une rhinorrhée unilatérale. Le diagnostic nécessite un bilan clinique et radiologique précis.
L’objectif de ce travail est de rapporter les attitudes diagnostique et thérapeutique face à une sinusite maxillaire en rapport avec un dépassement de gutta chez une patiente prise en charge au service d’odontologie chirurgicale du CCTD de Casablanca.
Detection of multi-antibiotic resistant Vibrio parahaemolyticus isolated from fresh produce in Dhaka, Bangladesh
Authors: AKTER SUMI , Zuhura Fatema , Ferdous Zannatul , Hossain Md , Ahsan Md , Salam Md
Published: February 2024

The demand for fresh produce is rising daily as it's an excellent way to maintain a healthy lifestyle. The current work fixed the target employing culture-based and molecular techniques for isolating and identifying the pathogenic Vibrio parahaemolyticus from fresh produce. The colonial appearance on TCBS agar and CHROMagar culture plates revealed the prevalence of Vibrio spp. and V. parahaemolyticus in all examined samples, which were 45/112 (40.2%) and 40/112 (35.7%), with the highest load of up to 2.0x105cfu/g and 6.4x103cfu/g, respectively. Sixty isolates in all were chosen for further molecular characterization. Multiplex PCR results exhibited that all tested isolates were positive for tlh gene and six for tdh gene but none of isolate for trh gene. According to obtained data on antimicrobial susceptibility, the major portion of tested strains was found to be resistant to ampicillin (90%), tetracycline (80%), and streptomycin (70%). The range of the multiple antibiotic index was 0-0.33. This study finding revealed that the existence of potential pathogenic V. parahaemolyticus in tested fresh produce samples constitutes a risk to public health and consumer safety thus urging continued surveillance.