bluuebunny/crossref_metadata_2025 huggingface dataset:
Antioxidant Effect of Flavonoids Present in Euterpe oleracea Martius and Neurodegenerative Diseases: A Literature Review
Authors: de Oliveira Nayana Keyla Seabra , Almeida Marcos Rafael Silva , Pontes Franco Márcio Maciel , Barcelos Mariana Pegrucci , de Paula da Silva Carlos Henrique Tomich , Rosa Joaquín María Campos , Cruz Rodrigo Alves Soares , da Silva Hage-Melim Lorane Izabel
Published: May 2019

Introduction:

Neurodegenerative diseases (NDDs) are progressive, directly affecting the central nervous system (CNS), the most common and recurrent are Alzheimer's disease (AD) and Parkinson's disease (PD). One factor frequently mentioned in the etiology of NDDs is the generation of free radicals and oxidative stress, producing cellular damages. Studies have shown that the consumption of foods rich in polyphenols, especially those of the flavonoid class, has been related to the low risk in the development of several diseases. Due to the antioxidant properties present in the food, a fruit that has been gaining prominence among these foods is the Euterpe oleracea Mart. (açaí), because it presents in its composition significant amounts of a subclass of the flavonoids, the anthocyanins.

Methods:

In the case review, the authors receive a basic background on the most common NDDs, oxidative stress and antioxidants. In addition, revisiting the various studies related to NDDs, including flavonoids and consumption of açaí.

Results:

Detailed analysis of the recently reported case studies reveal that dietary consumption of flavonoid-rich foods, such as açaí fruits, suggests the efficacy to attenuate neurodegeneration and prevent or reverse the age-dependent deterioration of cognitive function.

Conclusion:

This systematic review points out that flavonoids presenting in açaí have the potential for the treatment of diseases such as PD and AD and are candidates for drugs in future clinical research. However, there is a need for in vitro and in vivo studies with polyphenol that prove and ratify the therapeutic potential of this fruit for several NDDs.
Design Process and Utilization of a Novel Clinical Decision Support System for Neuropathic Pain in Primary Care: Mixed Methods Observational Study (Preprint)
Authors: Guenter Dale , Abouzahra Mohamed , Schabort Inge , Radhakrishnan Arun , Nair Kalpana , Orr Sherrie , Langevin Jessica , Taenzer Paul , Moulin Dwight E
Published: May 2019

BACKGROUND

Computerized clinical decision support systems (CDSSs) have emerged as an approach to improve compliance of clinicians with clinical practice guidelines (CPGs). Research utilizing CDSS has primarily been conducted in clinical contexts with clear diagnostic criteria such as diabetes and cardiovascular diseases. In contrast, research on CDSS for pain management and more specifically neuropathic pain has been limited. A CDSS for neuropathic pain has the potential to enhance patient care as the challenge of diagnosing and treating neuropathic pain often leads to tension in clinician-patient relationships.

OBJECTIVE

The aim of this study was to design and evaluate a CDSS aimed at improving the adherence of interprofessional primary care clinicians to CPG for managing neuropathic pain.

METHODS

Recommendations from the Canadian CPGs informed the decision pathways. The development of the CDSS format and function involved participation of multiple stakeholders and end users in needs assessment and usability testing. Clinicians, including family medicine physicians, residents, and nurse practitioners, in three academic teaching clinics were trained in the use of the CDSS. Evaluation over one year included the measurement of utilization of the CDSS; change in reported awareness, agreement, and adoption of CPG recommendations; and change in the observed adherence to CPG recommendations.

RESULTS

The usability testing of the CDSS was highly successful in the prototype environment. Deployment in the clinical setting was partially complete by the time of the study, with some limitations in the planned functionality. The study population had a high level of awareness, agreement, and adoption of guideline recommendations before implementation of CDSS. Nevertheless, there was a small and statistically significant improvement in the mean awareness and adoption scores over the year of observation (P=.01 for mean awareness scores at 6 and 12 months compared with baseline, for mean adoption scores at 6 months compared with baseline, and for mean adoption scores at 12 months). Documenting significant findings related to diagnosis of neuropathic pain increased significantly. Clinicians accessed CPG information more frequently than they utilized data entry functions. Nurse practitioners and first year family medicine trainees had higher utilization than physicians.

CONCLUSIONS

We observed a small increase in the adherence to CPG recommendations for managing neuropathic pain. Clinicians utilized the CDSS more as a source of knowledge and as a training tool than as an ongoing dynamic decision support.
Luchas y armamentos en la conquista de la Isla de Santo Domingo
Authors: Ruiz B. Víctor Eddy
Published: May 2019

En esta ponencia se plantea que entre los habitantes de la Isla de Santo Domingo y los españoles llegados en 1492 había una profunda diferencia tecnológica a nivel del armamento de guerra Esa diferencia le permitió a los segundos imponerse en el plano militar y consecuentemente les permitió dominar política y socialmente a los indígenas. Este triunfo militar repercutió de forma decisiva sobre la evolución tecnológica moderna al garantizar la transferencia de las grandes riquezas de América a los europeos.
Las tecnologías tradicionales en las sociedades latinoamericanas 500 años después del descubrimiento: el punto de vista de la antropología
Authors: Castillo Luciano
Published: May 2019

Este texto de Luciano Castillo reflexiona sobre las tecnologías tradicionales en las sociedades latinoamericanas 500 años despues del descubrimiento. Muestra demás que la tecnología está considerada como una categoría de la cultura importante, mientras que otros la colocan dentro de la cultura material.
Impacto técnico ambiental del descubrimiento: lecciones para la educación ambiental
Authors: Chantada Amparo
Published: May 2019

Este texto de Amparo Chantada analiza la educación ambiental, la cual trata de servir de instrumento en el ambiente de decisiones sobre el desarrollo y las implicaciones ambientales.
Perfil del el/la maestro/a del programa de capacitación INTEC-EDUCA-PIPE
Authors: Castillo Díaz Gineida
Published: May 2019

En la revisión de la literatura sobre los factores que inciden en la calidad de la educación, una de las premisas centrales que emerge es la necesidad de mejorar sustancialmente la calidad profesional de quienes enseñan. Igualmente, la construcción de un nuevo modelo educativo acorde a los requerimientos del año 2000, coloca en el umbral de la discusión, el mejoramiento del perfil y la situación actual de la profesión docente. El garantizar y mejorar los aprendizajes de los alumnos, discurso expreso en nuestra propuesta curricular, también implica asegurar un maestro con condiciones, oportunidades conciencia de su profesión, como bien están planteados en los documentos de la iniciativa "Educación para Todos" Sin embargo, el perfil real de los docentes de la educación básica en nuestro país está lejos de lo que se supone debe ser y la que se aspira para producir las reformas educativas que aseguren una educación de calidad El debate y las demandas de quienes dicen defender los y las maestros/as se ha centrado sólo en lo que son las condiciones salariales y de vida, dejando de un lado aspectos tales como sus opiniones, creencias, interpretación y percepción sobre la profesión y la realidad educativa, y su incidencia en el proceso de enseñanza y aprendizaje El presente estudio tiene como propósito fundamental presentar un perfil de el/la maestro/a-estudiante que participa en el Programa de Capacitación para Maestros/as Normales, INTEC-EDUCA-PIPE. Dicho estudio está dirigido a la comprensión de la situación del docente y de su interpretación de la realidad educativa y profesional. Esto es importante, tanto el/la maestro/a es uno de los actores fundamentales del proceso educativo, quien interpreta los planteamientos del sistema educativo en la práctica que desarrolla en el aula, espacio donde ocurren los procesos de innovaciones y concreciones de los esfuerzos que se realizan para mejorar el sistema escolar Este informe consta de las siguientes secciones: una primera parte preferida a los antecedentes, objetivos y metodología. En segundo lugar, se presentan los resultados y, por último, las conclusiones y sus implicaciones.
Diseño de secciones sometidas a flexión compuesta, con gran excentricidad según el reglamento ACI 318-02
Authors: Perdomo Fernando A.
Published: May 2019

Descripción de los cambios más significativos en el nuevo Reglamento de las Construcciones para Hormigón Estructural ACI 318-02, en lo referente al diseño de secciones de hormigón armado sometidas a flexión y flexión compuesta con gran excentricidad Se presenta la deducción de las fórmulas básicas para el diseño de secciones de hormigón armado usando los nuevos criterios introducidos en el Reglamento, así como las nuevas tablas de coeficientes para diseño.
Diógenes Abreu. Perejil : el ocaso de la hispanidad dominicana ; celebración de la multiplicidad cultural desde New York
Authors: Alvarez López Luis
Published: May 2019

Este texto analiza los centrales pensamientos de la obra "Perejil: el ocaso de la hispanidad dominicana" de Diógenes Abreu, la cual es una obra crítica contundente y demoledora contra la premiada publicación de Manuel Nuñez "El Ocaso de la Nación Dominicana".
Reformas económicas y negociaciones políticas : apuntes sobre la experiencia dominicana de los noventa
Authors: Andújar Scheker Julio G.
Published: May 2019

A mediados de la década del noventa se discutieron en el Congreso Dominicano ajustes estructurales que formaban parte de lo que sería una segunda generación de reformas económicas. Los principales participantes en esa discusión fueron los grupos empresariales organizados, los partidos políticos y las firmas de consultoría económica. La interacción de estos grupos en el marco de las vistas públicas Congresionales contiene los elementos más importantes de la economía política de las reformas dominicanas. Este trabajo analiza esas interacciones a la vez que discute la consistencia y relevancia de las políticas propuestas. El documento explica los orígenes de los grupos de presión anti-reforma durante los años de vigencia de la industrialización por sustitución de importaciones y analiza los mecanismos utilizados históricamente por estos grupos para dilatar la aprobación de reformas importantes. Se concluye que la experiencia, el nivel organizacional y el tamaño relativo de los grupos de interés son determinantes para el avance de las reformas económicas en países en desarrollo. Este resultado es consistente con los modelos teóricos de la llamada nueva economía política de las reformas.
Third Canadian Therapeutics Congress
Authors: Pharmacolog Canadian Journal of Clinical
Published: May 2019

Absracts

THE CANADIAN THERAPEUTICS CONGRESS

“THERAPEUTICS EVOLVING: BRINGING THE SCIENCE

OF INNOVATIVE TREATMENTS INTO OUR EVERYDAY WORLD”
INOVAÇÃO TECNOLÓGICA E OS DESAFIOS PARA UMA CONTABILIDADE INTERATIVA: ESTUDO DOS ESCRITÓRIOS DE CONTABILIDADE DO ESTADO DE SANTA CATARINA
Authors: Da Silva Cilda Giese , Eyerkaufer Marino Luiz , Rengel Rodrigo
Published: May 2019

O objetivo deste estudo consiste na identificação dos desafios para a contabilidade interativa diante dos avanços tecnológicos, observando os escritórios do estado de Santa Catarina. Os dados do survey revelam que a Tecnologia da Informação (TI) proporcionou a oferta de novos produtos aos seus clientes, além de informações mais ágeis e seguras o que permite maior integração de informações entre os escritórios e seus clientes. A vinda da internet foi considerada pela maioria dos respondentes como a maior inovação tecnológica para os escritórios de contabilidade, no entanto, também elevou os gastos operacionais devido à necessidade de melhorias continuas na qualidade dos serviços. A complexidade dos serviços e o aumento das tarefas com o advento da tecnologia, sem aumento no valor dos honorários, revelam que economicamente as evoluções tecnológicas não proporcionaram maior lucratividade para os escritórios. Conclui-se que os principais desafios da TI para os escritórios é fazer uso da internet para otimizar as tarefas, preparar-se diante da complexidade dos serviços exigidos, além de buscar maior interação com os clientes, ao mesmo tempo que oportunidades também podem ser vistas, a exemplo da disponibilização de novos serviços e o atendimento a novos mercados.
AVALIAÇÃO DO DESENVOLVIMENTO DA METODOLOGIA DE APRENDIZAGEM BASEADA EM PROBLEMAS NA DISCIPLINA DE CONTABILIDADE NO CURSO DE TÉCNICO EM ADMINISTRAÇÃO
Authors: Eifler André Luis , Ahlert Edson Moacir
Published: May 2019

O professor precisa ser criativo e flexível em escolher procedimentos visando integrar o conteúdo, a disponibilidade do tempo e as particularidades de cada assunto, possibilitando um melhor desenvolvimento da capacidade cognitiva dos alunos. A presente pesquisa, de cunho descritiva e abordagem quanti-qualitativa, embasada em pesquisa bibliográfica e levantamento de dados, objetivou destacar a utilização da Aprendizagem Baseada em Problemas, nas aulas da disciplina de Contabilidade, no curso Técnico em Administração, do Centro de Educação Profissional da Universidade do Vale do Taquari – Univates. Buscou-se também descrever o desenvolvimento da metodologia ativa utilizada com o grupo de alunos num intervalo de três aulas, bem como investigar as percepções quanto à eficiência do método, por meio de um questionário. Os dados sugerem que os alunos perceberam que aprendem melhor, quando participam de forma ativa e desafiadora, em condições de aplicar o aprendizado experimentado em sala de aula em situação que se apresentam nas empresas onde atuarão. Os respondentes afirmam, em sua maioria, que percebem a estratégia de ensino utilizada como aspecto favorável ao bom funcionamento da dinâmica em sala de aula, e êxito no relacionamento entre professor e alunos.
ANÁLISE DA ENVIRONMENTAL DISCLOSURE DE CORPORAÇÕES COM SELO ISE DA BM&FBOVESPA
Authors: Alberton Andréia , Feil Alexandre André
Published: May 2019

As corporações, em nível mundial, estão sendo pressionadas por diversos stakeholders para evidenciarem informações ambientais positivas e negativas nos relatórios contábeis/sociais. Neste contexto, este estudo objetiva analisar a environmental disclosure nas corporações com selo Índice de Sustentabilidade Empresarial (ISE) da BM&FBovespa. A metodologia empregada é a quantitativa, descritiva-exploratória e tem como procedimento técnico a documental, sendo a coleta de dados efetuada mediante checklist. Os principais resultados revelam que as evidenciações das informações ambientais ocorrem, em maior quantidade, no relatório de sustentabilidade, por outro lado, estas informações são escassamente evidenciadas no balanço patrimonial e na demonstração do resultado do exercício. As informações ambientais positivas são evidenciadas em sua maioria e poucas evidenciaram informações ambientais negativas. A evidenciação das informações ambientais diverge entre as corporações analisadas, não detectando padrões de informações divulgadas. As corporações com selo ISE com prejuízo contábil tiveram maior divulgação de informações ambientais quanto à quantidade de relatórios, o que se constatou através de uma correlação significativa. Conclui-se que as corporações com selo ISE possuem uma escassa environmental disclosure das informações ambientais, em especial, nos relatórios contábeis.
ANÁLISE DO MERCADO DE TRABALHO A PARTIR DA PERCEPÇÃO DE PESSOAS DESEMPREGADAS
Authors: Debortoli Sonimara , Diehl Liciane , Braido Gabriel Machado
Published: May 2019

Conquistar uma vaga de emprego tem sido um grande desafio nos últimos tempos devido à crise econômica que o Brasil está passando. Assim, este estudo propõe analisar a percepção de pessoas desempregadas em relação à atual situação do mercado de trabalho. Busca também compreender os reais motivos do aumento significativo da taxa de desemprego e apontar os impasses entre oferta e procura de emprego. Para tanto, foram aplicados questionários com questões fechadas e uma aberta a sujeitos desempregados do Vale do Taquari/RS, caracterizando essa pesquisa como quantitativa e qualitativa. Os resultados demonstraram que o desemprego afeta pessoas sem distinção de gênero, idade e grau de escolaridade, e que, mesmo estando desempregadas, as pessoas estão otimistas em relação às perspectivas de conseguir um trabalho, permanecem constantemente na busca por uma vaga e por qualificação. Para se manterem financeiramente, buscam alternativas de renda em atividades informais e contam com a ajuda de pessoas próximas. Ainda, destacam que as exigências por parte das empresas no momento da seleção estão cada vez mais rigorosas, demandam pessoas com experiência e qualificações específicas, banindo muitas de conseguir uma oportunidade. Este estudo mostrou-se importante na medida em que ampliou o conhecimento referente à atual situação do mercado de trabalho e a situação do desemprego que afeta uma grande diversidade de pessoas e aumenta cada vez mais a concorrência por uma vaga, sendo assim imprescindível conhecimento e qualificação para estar à frente do mercado.
Hacia una cartografía del dispositivo democrático global
Authors: Cuadro Mariela
Published: May 2019

El texto parte de la sospecha de la existencia de un dispositivo democrático que funciona globalmente. Basándose en Michel Foucault, concibe al dispositivo como una red que conecta elementos heterogéneos y cuyo efecto es la producción de subjetividades. Así, haciendo un uso metodológico del mismo, vincula proposiciones éticas sobre la libertad, construcciones teóricas de las relaciones internacionales, prácticas políticas de Estados y organismos internacionales, y construcciones normativas (específicamente, la responsabilidad de proteger) que acompañan las intervenciones internacionales en el Sur global, para reflexionar sobre la producción de un sujeto democrático, predicado de un gobierno liberal global.
Hay más ciencias que las naturales
Authors: García González Juan A.
Published: May 2019

En este trabajo se contrapone a las explicaciones naturalistas de la conciencia las de otros tipos de saber; en concreto, los saberes más teóricos, como la filosofía, los saberes históricos y las ciencias formales, como la lógica y la matemática, en especial la geometría. Se aspira a mostrar con ello que la conciencia, inexplicada por las ciencias naturales, no por ello nos resulta desconocida.
Máquinas computacionales y conciencia artificial
Authors: Génova Fuster Gonzalo
Published: May 2019

En este ensayo argumento que la noción de máquina incluye necesariamente el hecho de ser diseñada con un fin. Por tanto, no basta con ser sistema mecánico para ser máquina. Puesto que el método científico-experimental excluye metodológicamente la consideración de la finalidad, resulta que también es insuficiente para entender cabalmente qué son las máquinas. Por el contrario, para entender una máquina es necesario ante todo entender su finalidad (y también su estructura), en claro paralelismo con la causa final (y la formal) de Aristóteles. Obviamente, la finalidad y la estructura no son componentes de la máquina que puedan interaccionar físicamente con otros componentes, y sin embargo son esenciales para comprender su funcionamiento. Esto arroja una interesante luz sobre la relación entre la mente y el cuerpo: de modo análogo a como la finalidad de un artefacto explica su funcionamiento, la conciencia es la explicación del comportamiento específicamente humano. Máquinas y seres humanos tienen en común que, para entenderlos, es necesario acudir al principio de finalidad. Pero mientras en las máquinas es una finalidad dada, los seres humanos nos caracterizamos porque podemos proponernos nuestros propios fines.
Principios físicos, biológicos y cognoscitivos
Authors: Padial Juan J.
Published: May 2019

Las teorías científicas son explicativas, es decir adoptan una perspectiva nomológica-deductiva, intentando generalizar rigurosamente desde datos empíricos, que por exteriores son intersubjetivamente contrastables. Esta perspectiva es común tanto a los enfoques externalistas como a los internalistas en biología. Recientemente, la biosemiótica ha introducido la idea de agente biológico que actúa como sí fuese consciente. Y esto implica una naturalización de la conciencia. Sostengo que en las filosofías de Whitehead y Leonardo Polo cabe encontrar fundamentos no naturalizables de la actividad «semiótica» de los organismos vivos.
La alteridad mal explicada: Una visión alternativa sobre el problema de las otras mentes
Authors: Fernández Borsot Gabriel
Published: May 2019

Tomando como punto de partida la tesis de Arana en La conciencia inexplicada (de que la conciencia es inexplicable por métodos naturalistas), la ponencia defiende una visión de la capacidad de alteridad en el ser humano como acoplamiento de dos componentes: la conciencia primordial e inexplicable que Arana analiza, y la capacidad estructural innata del ser humano para la mutualidad. La ponencia critica las explicaciones que la ciencia cognitiva ha dado a la cuestión de la alteridad, para posteriormente proponer una explicación alternativa, proporcionando evidencias empíricas y soporte teórico.
La cultura: ¿liturgia o akelarre?
Authors: Insausti Gabriel
Published: May 2019

La cultura contemporánea abunda en expresiones sacrílegas, blasfemas o simplemente repugnantes, que persiguen deliberadamente suscitar un equívoco repudio en el espectador; a menudo sus celebraciones consisten en un aquelarre, una celebración o exaltación del mal que aparece como inversión de la liturgia religiosa, hasta el extremo de que el productor o consumidor de cultura judeocristiano puede llegar a sentir que se enfrenta a una disyuntiva: participar de la cultura de su tiempo o participar de su religión.
La primacía entre arte, religión y filosofía. Un debate abierto desde el Romanticismo
Authors: Cascales Tornel Raquel
Published: May 2019

El Romanticismo miró la Ilustración como una época que, al apostar por la racionalidad de manera casi exclusiva, rompió la unidad entre distintos ámbitos del saber. La conciencia de esa falta de unidad impulsa la reflexión de muchos intelectuales sobre cómo volver a alcanzarla, tarea que al principio los románticos hacen recaer en el arte. En concreto, el grupo de los Nazarenos, muy ligado al Athenäum, apostó por recuperar esta unidad, que pronto adquirió tintes políticos, mediante la “religión del arte”. También otros autores idealistas, como Schelling, consideraron que el arte debía ocupar el lugar primordial en el sistema filosófico. Frente a ellos destaca la figura de Hegel, que rechazará cada vez con más fuerza la mistificación romántica del arte. Aunque, como se verá, en un inicio Hegel también habla de la “religión del arte”, en su obra de madurez distingue entre arte, religión y filosofía, dejando claro el lugar primordial que ocupa la racionalidad filosófica en su sistema. Revisando estas cuestiones desde la perspectiva más contemporánea, Inciarte considera que, a pesar de la rotundidad del pensamiento hegeliano, estas tensiones no pueden quedar resueltas desde un enfoque meramente reflexivo, sino que sólo encuentran una salida cuando se tratan en el nivel práctico de la vida.
Libertad humana y libertad divina. Una lectura de 'Cultura y verdad' a la luz de 'La imaginación trascendental'
Authors: Solans Blasco Miquel
Published: May 2019

Esta contribución ofrece un análisis del tratamiento de la experiencia de conflicto entre las pretensiones de realización de la libertad humana, de un lado, y el reconocimiento de la libertad divina y su poder respecto de la propia vida, de otro, así como de la naturaleza de su resolución tal y como los presenta Fernando Inciarte en dos de sus obras: Cultura y Verdad y La imaginación trascendental en la vida, en el arte y en la filosofía. La tesis principal es que la reconciliación entre ambas libertades es imposible en términos humanos y que, sin embargo, cierta forma de vivir orientada por el reconocimiento de esta misma imposibilidad abre al hombre a su resolución
La conciencia explicada desde la ciencia experimental. Método científico y subjetividad
Authors: Sánchez Tajadura Beatriz
Published: May 2019

El método científico se centra en estudiar lo objetivo, lo empírico, lo cuantificable. Pero a la hora de explicar la consciencia humana, el método científico es insuficiente. La consciencia es de naturaleza subjetiva, no objetiva. El lenguaje y el arte, en especial el literario, suponen una vía alternativa para comprender la subjetividad. El estudio del lenguaje es un punto de vista multidisciplinar que atiende no solo a la materia, como hace el método científico, sino también a la forma. Este artículo sugiere un punto de vista más amplio para estudiar la consciencia humana.
Sobre la importancia de lo vero-símil y de la imaginación en el mito platónico para la captación del mundo como imagen de las ideas
Authors: Inciarte Fernando
Published: May 2019

Este artículo se ocupa de las relaciones del intelecto filosófico con la verdad o las enseñanzas contenidas en la religión positiva. Para ello, centra, en un primer lugar, la atención en algunos textos platónicos en los que Sócrates revela su actitud respecto de lo religioso, especialmente en la Apolo-gía, Cratilo y Fedro. En un segundo momento, a partir de una lectura novedosa de algunos pasajes centrales del Sofista y del Timeo, se busca justificar el carácter autónomo y de auténtico conocimiento de la filosofía, en cuanto explicación de la realidad como imagen de las ideas. Ahí encuentra el autor la auténtica perspectiva desde la que el hombre puede acercarse al conocimiento del mundo y de las cosas divinas.
Graph Theory Teaches Us Something About Grammaticality
Authors: Arikawa Koji
Published: May 2019

Graph theory, which quantitatively measures the precise structure and complexity of any network, uncovers an optimal force balance in sentential graphs generated by the computational procedures of human natural language (CHL). It provides an alternative way to evaluate grammaticality by calculating ‘feature potential’ of nodes and ‘feature current’ along edges. An optimal force balance becomes visible by expressing ‘feature current’ through different point sizes of lines. Graph theory provides insights into syntax and contradicts Chomsky’s current proposal to discard tree notations. We propose an error minimization hypothesis for CHL: a good sentential network possesses an error-free self-organized force balance. CHL minimizes errors by (a) converting bottom-up flow (structure building) to top-down flow (parsing), (b) removing head projection edges, (c) preserving edges related to feature checking, (d) deleting DPmovement trajectories headed by an intermediate copy, (e) ensuring that covert wh-movement trajectories have infinitesimally small currents and conserving flow directions, and (f) robustly remedying a gap in wh-loop by using infinitesimally inexpensive wh-internally-merged (wh- IM) edge with the original flow direction. The CHL compels the sensorimotor (SM) interface to ground nodes so that Kirchhoff’s current law (a fundamental balance law) is satisfied. Internal merges are built-in grounding operations at the CHL–SM interface that generate loops and optimal force balance in sentential networks.
Market Power And Efficiency Of Commercial Banks In Indonesia
Authors: Wita Juwita Ermawati Eny Susilowati, Budi Purwanto,
Published: May 2019

In order to encourage credit growth that experienced sluggishness from 2012 to 2016, Bank Indonesia sought to increase lending by lowering the benchmark interest rate so that it could be followed by a decline in lending rates by banks in Indonesia. But this is thought to cause competition to become a low oligopoly and decrease efficiency. This study aims to determine the factors that affect the amount of credits paid, estimating the market power and efficiency of commercial banks in Indonesia for the 2012-2016 period. Efficiency method used is Data Envelopment Analysis, while to estimate market power using two stage least square. The results of the demand equation show GDP and WCCR_GDP have no significant effect while the rest variables have significant effect. From the two equations using Bresnahan-Lau’s model, market power is 0.231. Efficiency measurement obtained a good efficiency scale even reaching 100% in 2013, 2015 and 2016.
The Rose of Dermatology
Authors: Marion Tyler , Gibbons Jake Alan
Published: May 2019

Not available.
Myeloid sarcoma - a case report
Authors: Varra Vamsi , Rodriguez Marla , Beal Brandon , Fernandez Anthony
Published: May 2019

Not available.
Crohn's Disease Presenting as Isolated Lower Lip Swelling
Authors: Hosking Anna-Marie , Chapman Lance , Smith Janellen
Published: May 2019

Not available.
Using Cost-Effective Density Functional Theory (DFT) to Calculate Equilibrium Isotopic Fractionation for Reactions Involving Large Organic Molecules
Authors: Iron Mark , Gropp Jonathan
Published: May 2019

With an eye towards applications in environmental sciences, the factors impacting the accuracy of calculating equilibrium isotopic fractionation α are considered. α is calculated from the reduced partition function relation β via the vibrational frequencies. Density-fitting (DF, or resolution of the identity – RI) is a popular tool to help reduce the cost of DFT energy calculations, and its impact on the accuracy of calculating vibration frequencies was determined to be negligible provided one uses a sufficiently large auxiliary density-fitting basis set. Using a set of high-accuracy fractionations for a series of small molecules, the accuracy of several density-functional theory (DFT) exchange–correlation functionals in calculating β was considered. Based on these results, a selection of functionals was tested against two benchmark databases of isotopic fractionations that were generated, one for D/H fractionation (HEIF11) and one for heavy-atom fractionation (CNOEIF35). It was found that, with the def2-TZVP basis set, O3LYP had the lowest mean absolute deviation (21‰ and 3.9‰, respectively), but the GGA/meta-GGA functionals τHCTHD3BJ, τHCTH and HCTH have almost similar performances (22‰ and 4.1‰, respectively, for τHCTHD3BJ). In this work we provide a roadmap to predict for equilibrium isotopic fractionations of large organic molecules, and constrain their potential uncertainties.
To Bend or Not to Bend, the Dilemma of Multiple Bonds
Authors: Pizzocchero Michele , Bonfanti Matteo , Martinazzo Rocco
Published: May 2019

The manuscript addresses the issue of the structural distortions occurring at multiple bonds between high main group elements, focusing on group 14. These distortions are known as trans-bending in silenes, disilenes and higher group analogues, and buckling in 2D materials likes silicene and germanene. A simple but correlated \sigma + \pi model is developed and validated with first-principles calculations, and used to explain the different behaviour of second- and higher- row elements.
H2O as the Sole Hydrogen Source for Ni-Catalyzed Reduction of Alkenes
Authors: Wu Yichen , liu Tao , Chen Dongping , Wang Daoming , Wang Peng
Published: May 2019

Herein, we reported a nickel catalyzed hydrogenation of alkenes with water as the sole hydrogen source. Employing Zn as reductant and water as solvent in the presence of a catalytic amount of nickel catalyst led to direct hydrogenation of a series of electron-rich and electron-deficient alkenes in high yields. This protocol features unprecedented heterocycle and functional group tolerance under facile and mild conditions. Selective hydrogenation of the substrates containing additional reducible functionalities, such as alkenyl, alkynyl, chloride, ketone, and benzyl group etc, was also realized.
Local Structure Order Parameters and Site Fingerprints for Quantification of Coordination Environment and Crystal Structure Similarity
Authors: Zimmermann Nils , Jain Anubhav
Published: May 2019

Structure characterization and classification is frequently based on local environment information of all or selected atomic sites in the crystal structure. Therefore, reliable and robust procedures to find coordinated neighbors and to evaluate the resulting coordination pattern (e.g., tetrahedral, square planar) are critically important for both traditional and machine learning approaches that aim to exploit site or structure information for predicting materials properties. Here, we introduce new local structure order parameters (LoStOPs) that are specifically designed to rapidly detect rotationally symmetric (e.g., tetrahedron) as well as asymmetric local coordination environments (e.g., square pyramid). Furthermore, we introduce a Monte Carlo optimization approach to ensure that the different LoStOPs are comparable with each other. We then apply the new local environment descriptors to define site and structure fingerprints and to measure similarity between 61 known coordination environments and 40 commonly studied crystal structures, respectively. After extensive testing and optimization, we determine the most accurate structure similarity assessment procedure to compute all 2.45 billion structure similarities between each pair of the ≈ 70,000 materials that are currently present in the Materials Project database.
Towards Understanding the Different Influences of Grain Boundaries on Ion Transport in Sulfide and Oxide Solid Electrolytes
Authors: Dawson James , Canepa Pieremanuele , Clarke Matthew , Famprikis Theodosios , Ghosh Dibyajyoti , Islam Saiful
Published: May 2019

Solid electrolytes provide a route to the development of all-solid-state batteries that can potentially surpass the safety and performance of conventional liquid electrolyte-based devices. Sulfide solid electrolytes have received particular attention as a result of their high ionic conductivities. One of the main reasons for such high ionic conductivity is the apparently reduced grain boundary resistance of sulfide solid electrolytes compared to their oxide counterparts, but this is not fully established. Using two model electrolyte systems, Na3PS4 and Na3PO4, we apply a novel microscale simulation approach to analyze ionic transport in polycrystalline materials with various grain volumes. For Na3PO4, high grain boundary resistance is found, with the Na-ion conductivity decreasing with decreasing grain volume. For Na3PS4, the overall influence of grain boundaries is significantly reduced compared to the oxide. Detailed analysis reveals a minimal change in the local structures and Na-ion conduction mechanism between bulk and polycrystalline Na3PS4, whereas the change is far more substantial for Na3PO4, with evidence of over-coordination of Na ions at the grain boundaries. Our microscale approach helps to explain the fundamentally different influences of grain boundaries on ion transport in phosphate and thiophosphate solid electrolytes.
Catalytic Direct Amidations in tert-Butyl Acetate Using B(OCH2CF3)3
Authors: Coomber Charlotte , Laserna Victor , Martin Liam , Smith Peter , Hailes Helen C. , Porter Michael , Sheppard Tom
Published: May 2019

Catalytic direct amidation reactions have been the focus of considerable recent research effort, due to the widespread use of amide formation processes in pharmaceutical synthesis. However, the vast majority of catalytic amidations are performed in non-polar solvents (aromatic hydrocarbons, ethers) which are typically undesirable from a sustainability perspective, and are often poor at solubilising polar carboxylic acid and amine substrates. As a consequence, most catalytic amidation protocols are unsuccessful when applied to polar and/or functionalised substrates of the kind commonly used in medicinal chemistry. In this paper we report a practical and useful catalytic direct amidation reaction using tert-butyl acetate as the reaction solvent. The use of an ester solvent offers improvements in terms of safety and sustainability, but also leads to an improved reaction scope with regard to polar substrates and less nucleophilic anilines, both of which are important components of amides used in medicinal chemistry. An amidation reaction was scaled up to 100 mmol and proceeded with excellent yield and efficency, with a measured process mass intensity of 8.
Assessing Many-Body Effects of Water Self-Ions. II: H3O+(H2O)n Clusters
Authors: Egan Colin K. , Lab Paesani
Published: May 2019

The importance of many-body effects in the hydration of the hydronium ion (H3O+) is investigated through a systematic analysis of the many-body expansion of the interaction energy carried out at the coupled cluster level of theory for the low-lying isomers of H3O+(H2O)n clusters with n = 1 − 5. This is accomplished by partitioning individual fragments extracted from the whole clusters into “groups” that are classified by both the number of H3O+ and water molecules and the H-bonding connectivity within a given fragment. Effects due to the presence of the Zundel ion, (H5O2)+, are analyzed by further partitioning fragment groups by the “context” of their parent clusters. With the aid of the absolutely localized molecular orbital energy decomposition analysis (ALMO EDA), this structure-based partitioning is found to largely correlate with the character of different many-body interactions, such as cooperative and anticooperative hydrogen-bonding, within each fragment. This analysis emphasizes the importance of a many-body representation of inductive electrostatics and charge transfer in modeling the hydration of an excess proton in water. The comparison between the reference coupled cluster many-body interaction terms with the corresponding values obtained with various exchange-correlation functionals demonstrates that many of these functionals yield an unbalanced treatment of the H3O+(H2O)n configuration space.
Model galat spasial untuk jumlah produksi padi tahun 2014 di jawa barat
Authors: Lumbantoruan Alicia Anggelia , Setiawan Adi , Susanto Bambang
Published: May 2019

Indonesia merupakan salah satu negara penghasil padi sehingga luas lahan yang ditanami padi merupakan faktor utama yang mempengaruhi produksi padi. Pada studi ini, diusulkan Model Galat Spasial (Spatial Error Model) dalam penerapan untuk jumlah produksi padi dan jumlah produksi padi tetangga. Model ini mengasumsikan bahwa galat (error) dalam model memiliki hubungan spasial antara satu wilayah dan wilayah lain. Data yang digunakan adalah luas lahan produksi padi dan jumlah produksi padi di setiap kabupaten di Jawa Barat pada tahun 2014. Matriks pembobot juga digunakan dalam menggambarkan kedekatan antar wilayah. Hasil yang diperoleh dari model spasial diketahui bahwa konstanta dan juga jumlah total produksi wilayah tetangga tidak berpengaruh terhadap produksi padi suatu wilayah. Regresi sederhana tanpa konstanta adalah model terbaik untuk memodelkan jumlah produksi tanaman padi yang hanya bergantung pada luas lahan  produksi sehingga model galat spasial tidak dapat digunakan dalam kasus ini.
Optimizing Inventory for Chicken Egg Livestock Industry
Authors: Rikardo Cherish , Tan Alfian , Ariningsih Paulina Kus
Published: May 2019

This study is to give an alternative of an optimum inventory model for chicken egg livestock industry. The characteristic of the egg livestock industry is very unique; since the chicken breeding performance varies. In a particular span of time, the industry might have ameliorating and deteriorating characteristics. Some farmers nourish several generations at the same time. This study generates a mathematical model to optimize the length time between purchases of a chicken generation to get optimum cost by considering demand seasonality. This study is also generating the algorithm to find the optimum solution in a simple way. Future potential researches are also stated.Keywords: Optimization, inventory, egg, chicken, ameliorating
Perencanaan Produksi pada Produk Hollow dengan Ukuran 15 mm X 35 mm X 0.30 mm
Authors: Rosyidi Moh Ririn , Zabadi Fitri Fairus
Published: May 2019

PT Mulcindo is a manufacturing and service industry company works in the production of processed iron. This company produces corrugated steel sheet, iron canal, ceiling hanging guard rail, and partition frame.  However, the demand for this company was fluctuating.  Due to this fluctuation, PT Mulcindo Steel Industry has some problems such as product shortages or on the other hand product overload (over stock). This company is trying to find better production activities planning to fulfill market demand by using the right production planning. The results of the aggregate planning method in planning hollow production with a size of 15 mm x 35 mm x 0.30 mm in PT Mulcindo Steel Industry using the heuristic method, labor control with total aggregate planning costs of Rp. 674,937,732.2 / year, controlling sub-contracts with total aggregate planning costs of Rp. 822.136,585,3 / year, mix with overtime with total aggregate planning costs of Rp. 208,791,410.5 / year, Use of spreadsheets using regular production with trial and error techniques with total aggregate planning costs of Rp. 408,543,000 / year, the aggregate planning method in production planning obtained the minimum cost of Rp. 208,791,410.5 / year that is by using the heuristic method with mixed method completion techniques with over time. Keywords : Forecasting, Time Series, Aggregate Planning.
Efektivitas Penggunaan Instagram melalui Dua Tahap Analisis pada Zanana dan Oifyoo
Authors: Maharani Anastasya , Ardiansah Irfan , Pujianto Totok
Published: May 2019

The using of social media for marketing in products and services industry is currently trending, both in small and big enterprises. Zanana and Oifyoo are among the SMEs that already used Instagram to market their products. The purpose of this research is to find the effectiveness of using social media (Instagram) as online marketing on Zanana and Oifyoo. Zanana has a specified marketing team to manage their Instagram account> Meanwhile, Oifyoo's Instagram account is managed by the owner directly. The analysis of Instagram using effectiveness is much needed for increasing marketing, sales, or branding purposes. This research is done with a few steps including data reduction, data serving, conclusion, and verification. There are two data used in this research, primary and secondary data. The primary data is accumulated using in-depth interviews and the secondary data is retrieved on both SMEs Instagram accounts. This research used media and network analyses to analyze the data. The research shows that Zanana is more excelled at the effectiveness of using Instagram in both media and network analyses than Oifyoo. Keywords: effectiveness, Instagram, media analysis, network analysis
ANALISIS FAKTOR PRIORITAS MAHASISWA DALAM MEMILIH JURUSAN DENGAN FUZZY ANALITIC HIERARCHY PROCESS
Authors: Samosir Benny Sofyan , Novitasari Wiwik , Pasaribu Safran Efendi
Published: May 2019

University is the institution engaged in public service namely education services needs to identify the student candidates on education product, develops educational products and implements marketing activities to attract the attention of the student candidates. The purpose of this study is to determine priority consideration for students in choosing a study program at the College. The method used in this study is  Fuzzy Analysis Hierarchy Process (FAHP), with the results of the study, the order's rank criteria factor (Study Program profile, Infrastructure, The Activity of study Program and  Rules of Conduct), the rank order of the sub factor infrastructure criteria (Quality of College Building, Library, Sport Facilities, Laboratory), the order of sub-criteria rank factor of study Program profile ( lay out and Accreditation of study program, the length of the Study, Graduates Lecturer), a sequence of sub criteria ranking factors study program of activities  (Seminar, Community Service, fieldtrip, Research), and the sequence of sub-criteria rank factor of the order of  (Lectures, students number, Clothing, Leaves).
KEEFEKTIFAN MODEL STUDENT TEAM ACHIEVEMENT DIVISION (STAD) DAN E-LEARNING PADA MATERI OPERASI PENJUMLAHAN DAN PENGURANGAN PECAHAN DI SEKOLAH DASAR
Authors: Kadarwati Sri , Astutik Kasni , Prayitno Edi
Published: May 2019

The low learning outcomes of Addition and Reduction of Fractions in class IV are partly due to: (1) a tedious learning process, (2) lack of use of ICT as a source and media of learning. To overcome this problem the research team developed student-centered learning through e-learning learning in the Student Team Achievement Division (STAD) model. This study is a true experiment using the Pre-Test Group Control Post Test Design. The population is Sambiroto 02 elementary school students as many as 75 students in the 2017/2018 school year. The E2 group with EAD learning using the STAD model reached the highest mean value of the three groups, amounting to 88.67, followed by the E1 group with STAD learning at 74.54 and the K group with expository learning at 63.10. Regression analysis showed a positive relationship between motivation and activity with learning outcomes in groups E1 and E2 so it can be concluded that the higher the student's motivation and activity score the higher the student's learning achievement in addition and subtraction operations in elementary schools.
PENGEMBANGAN DESAIN PEMBELAJARAN BERBASIS PROBLEM POSING DALAM UPAYA MENINGKATKAN KEMAMPUAN PENALARAN KONSEP LINGKARAN PADA SISWA SMP KELAS VIII
Authors: Farman Farman , Yusryanto Yusryanto
Published: May 2019

This research aims to obtain a valid, practical, and effective instructional design of circle material for grade VIII of SMP-TQ Muadz Bin Jabal Kendari. Instructional design has developed based on Isman model (2011). To develop a design, learning devices and instruments were developed. The prototype were validated and the test showed by the average of validity value. The practicality was shown by the average percentage of achievement from the observation of teacher activity. The analysis result of the effectiveness of the design is measured based on the average of achievement from the observation of student activity, the average of circle reasoning ability and the average of the percentage of achievement of student responses questionnaire. Based on the finding, it can be concluded that the instructional design of circle material with Isman model for grade VIII of SMP-TQ Muadz Bin Jabal Kendari were valid, practice, and effective.
PROFIL KEMAMPUAN BERPIKIR KRITIS MATEMATIS SISWA DALAM PEMECAHAN MASALAH SOAL SPLDV DITINJAU DARI KEMAMPUAN MATEMATIKA
Authors: Asih Fitri Puji
Published: May 2019

The aim of this research is to describe profile crithical thinking ability of  the students in solving problem in Linear Equation System of Two Variables based on the criteria of critical thinking and problem solving ability of the students. This is qualitative research with the subject is the students in the class VIIIA of year 2018/2019 of SMP Negeri 6 Semarang. The data collection used is test and interview. Based on the results of this study it can be seen that the profile of critical thinking skills with the first subject of high math skills (SR) can do all category . Where the subject is moderate mathematics (SS) and the subject is low mathematics (SR) on indicators of critical thinking in problem solving that have not been done by student inference and strategy on subject SS on problems 2 and 3. While subject SR on problems 1,2 and 3.