bluuebunny/crossref_metadata_2025 huggingface dataset:
Singular behaviour of a rarefied gas on a planar boundary
Authors: Takata Shigeru , Funagane Hitoshi
Published: February 2013

Singular behaviour of a rarefied gas on a planar boundary is clarified on the basis of the Boltzmann equation. The thermal transpiration between two parallel plates is taken as a specific example. First, the flow velocity is shown to behave like$x\ln x$in the vicinity of the boundary, where$x$is a distance from the boundary. This implies a logarithmic divergence of the flow velocity gradient as$x\rightarrow 0$. Then, such a spatial singularity is shown to induce a similar singularity of the velocity distribution function (VDF) with respect to${\zeta }_{n} $on the boundary, where${\zeta }_{n} $is a normal component of the molecular velocity to the boundary. Moreover, the spatial singularity is shown to be quantitatively related to the discontinuity of the VDF on the boundary at${\zeta }_{n} = 0$. These macroscopic and microscopic singularities should be observed generally in a rarefied gas on a planar boundary.
Transient perturbation growth in time-dependent mixing layers
Authors: Arratia C. , Caulfield C. P. , Chomaz J.-M.
Published: February 2013

We investigate numerically the transient linear growth of three-dimensional (3D) perturbations in a homogeneous time-evolving mixing layer in order to identify which perturbations are optimal in terms of their kinetic energy gain over a finite, predetermined time interval. We model the mixing layer with an initial parallel velocity distribution $\mathbi{U}(y)= {U}_{0} \tanh (y/ d)\mathbi{e}_{x}$ with Reynolds number $Re= {U}_{0} d/ \nu = 1000$, where $\nu $ is the kinematic viscosity of the fluid. We consider a range of time intervals on both a constant ‘frozen’ base flow and a time-dependent two-dimensional (2D) flow associated with the growth and nonlinear saturation of two wavelengths of the most-unstable eigenmode of linear theory of the initial parallel velocity distribution, which rolls up into two classical Rayleigh instabilities commonly referred to as Kelvin–Helmholtz (KH) billows, which eventually pair to form a larger vortex. For short times, the most-amplified perturbations on the frozen $\tanh $ profile are inherently 3D, and are most appropriately described as oblique wave ‘OL’ perturbations which grow through a combination of the Orr and lift-up mechanisms, while for longer times, the optimal perturbations are 2D and similar to the KH normal mode, with a slight enhancement of gain. For the time-evolving KH base flow, OL perturbations continue to dominate over sufficiently short time intervals. However, for longer time intervals which involve substantial evolution of the primary KH billows, two broad classes of inherently 3D linear optimal perturbation arise, associated at low wavenumbers with the well-known core-centred elliptical translative instability, and at higher wavenumbers with the braid-centred hyperbolic instability. The hyperbolic perturbation is relatively inefficient in exploiting the gain of the OL perturbations, and so only dominates the smaller wavenumber (ultimately) core-centred perturbations when the time evolution of the base flow or the start time of the optimization interval does not allow the OL perturbations much opportunity to grow. When the OL perturbations can grow, they initially grow in the braid, and then trigger an elliptical core-centred perturbation by a strong coupling with the primary KH billow. If the optimization time interval includes pairing of the primary billows, the secondary elliptical perturbations are strongly suppressed during the pairing event, due to the significant disruption of the primary billow cores during pairing.
Disintegrating supercritical jets in a subcritical environment
Authors: Roy Arnab , Joly Clement , Segal Corin
Published: February 2013

Supercritical fluid injection using a single round injector into a quiescent atmosphere at subcritical and supercritical conditions was studied experimentally with particular attention paid to supercritical-into-subcritical injection and the reassertion of surface tension. The entire system was binary since the surrounding atmosphere consisted of an inert gas of a different composition than that of the injected fluid. Average densities and density gradients were quantified and a method was applied to quantify the resulting drop formation due to the disintegration of the jet based on the experimental conditions. The evolution of drop size with distance from the injector was identified.
Dynamics of particle settling and resuspension in viscous liquid films
Authors: Murisic N. , Pausader B. , Peschka D. , Bertozzi A. L.
Published: February 2013

We develop a dynamic model for suspensions of negatively buoyant particles on an incline. Our model includes settling due to gravity and resuspension of particles by shear-induced migration. We consider the case where the particles settle onto the solid substrate and two distinct fronts form: a faster liquid and a slower particle front. The resulting transport equations for the liquid and the particles are of hyperbolic type and we study the dilute limit for which we compute exact solutions. We also carry out systematic laboratory experiments, focusing on the motion of the two fronts. We show that the dynamic model predictions for small to moderate values of the particle volume fraction and the inclination angle of the solid substrate agree well with the experimental data.
Capillary breakup of a liquid torus
Authors: Mehrabian Hadi , Feng James J.
Published: February 2013

Capillary instability of a Newtonian liquid torus suspended in an immiscible Newtonian medium is computed using a Cahn–Hilliard diffuse-interface model. The main differences between the torus and a straight thread are the presence of an axial curvature and an external flow field caused by the retraction of the torus. We show that the capillary wave initially grows linearly as on a straight thread. The axial curvature decreases the growth rate of the capillary waves while the external flow enhances it. Breakup depends on the competition of two time scales: one for torus retraction and the other for neck pinch-off. The outcome is determined by the initial amplitude of the disturbance, the thickness of the torus relative to its circumference, and the torus-to-medium viscosity ratio. The linearly dominant mode may not persist till nonlinear growth and breakup. The numerical results are generally consistent with experimental observations.
Reynolds- and Mach-number effects in canonical shock–turbulence interaction
Authors: Larsson Johan , Bermejo-Moreno Ivan , Lele Sanjiva K.
Published: February 2013

The interaction between isotropic turbulence and a normal shock wave is investigated through a series of direct numerical simulations at different Reynolds numbers and mean and turbulent Mach numbers. The computed data are compared to experiments and linear theory, showing that the amplification of turbulence kinetic energy across a shock wave is described well using linearized dynamics. The post-shock anisotropy of the turbulence, however, is qualitatively different from that predicted by linear analysis. The jumps in mean density and pressure are lower than the non-turbulent Rankine–Hugoniot results by a factor of the square of the turbulence intensity. It is shown that the dissipative scales of turbulence return to isotropy within about 10 convected Kolmogorov time scales, a distance that becomes very small at high Reynolds numbers. Special attention is paid to the ‘broken shock’ regime of intense turbulence, where the shock can be locally replaced by smooth compressions. Grid convergence of the probability density function of the shock jumps proves that this effect is physical, and not an artefact of the numerical scheme.
Dynamics of the large-scale circulation in high-Prandtl-number turbulent thermal convection
Authors: Xie Yi-Chao , Wei Ping , Xia Ke-Qing
Published: February 2013

We report experimental investigations of the dynamics of the large-scale circulation (LSC) in turbulent Rayleigh–Bénard convection at high Prandtl number $\mathit{Pr}= 19. 4$ (and also $\mathit{Pr}= 7. 8$) and Rayleigh number $\mathit{Ra}$ varying from $8. 3\times 1{0}^{8} $ to $2. 9\times 1{0}^{11} $ in a cylindrical convection cell with aspect ratio unity. The dynamics of the LSC is measured using the multithermal probe technique. Both the sinusoidal-fitting (SF) and the temperature-extrema-extraction (TEE) methods are used to analyse the properties of the LSC. It is found that the LSC in high-$\mathit{Pr}$ regime remains a single-roll structure. The azimuthal motion of the LSC is a diffusive process, which is the same as those for $\mathit{Pr}$ around 1. However, the azimuthal diffusion of the LSC, characterized by the angular speed $\Omega $ is almost two orders of magnitude smaller when compared with that in water. The non-dimensional time-averaged amplitude of the angular speed $\langle \vert \Omega \vert \rangle {T}_{d} $ (${T}_{d} = {L}^{2} / \kappa $ is the thermal diffusion time) of the LSC at the mid-height of the convection cell increases with $\mathit{Ra}$ as a power law, which is $\langle \vert \Omega \vert \rangle {T}_{d} \propto {\mathit{Ra}}^{0. 36\pm 0. 01} $. The $\mathit{Re}$ number based on the oscillation frequency of the LSC is found to scale with $\mathit{Ra}$ as $\mathit{Re}= 0. 13{\mathit{Ra}}^{0. 43\pm 0. 01} $. It is also found that the normalized flow strength $\langle \delta \rangle / \mrm{\Delta} T\times \mathit{Ra}/ \mathit{Pr}\propto {\mathit{Re}}^{1. 5\pm 0. 1} $, with the exponent in good agreement with that predicted by Brown & Ahlers (Phys. Fluids, vol. 20, 2008, p. 075101). A wealth of dynamical features of the LSC, such as the cessations, flow reversals, flow mode transitions, torsional and sloshing oscillations are observed in the high-$\mathit{Pr}$ regime as well.
On the measurement of the turbulent diffusivity of a large-scale magnetic field
Authors: Tobias S. M. , Cattaneo F.
Published: February 2013

We argue that a method developed by Ångström (Ann. Phys. Chem., vol. 114, 1861, pp. 513–530) to measure the thermal conductivity of solids can be adapted to determine the effective diffusivity of a large-scale magnetic field in a turbulent electrically conducting fluid. The method consists of applying an oscillatory source and measuring the steady-state response. We illustrate this method in a two-dimensional system. This geometry is chosen because it is possible to compare the results with independent methods that are restricted to two-dimensional flows. We describe two variants of this method: one (the ‘turbulent Ångström method’) that is better suited to laboratory experiments and a second (the ‘method of oscillatory sines’) that is effective for numerical experiments. We show that, if correctly implemented, all methods agree. Based on these results we argue that these methods can be extended to three-dimensional numerical simulations and laboratory experiments.
Distributed lock-in drives broadband vortex-induced vibrations of a long flexible cylinder in shear flow
Authors: Bourguet Rémi , Karniadakis George Em , Triantafyllou Michael S.
Published: February 2013

A slender flexible body immersed in sheared cross-flow may exhibit vortex-induced vibrations (VIVs) involving a wide range of excited frequencies and structural wavenumbers. The mechanisms of broadband VIVs of a cylindrical tensioned beam of length-to-diameter aspect ratio 200 placed in shear flow, with an exponentially varying profile along the span, are investigated by means of direct numerical simulation. The Reynolds number is equal to 330 based on the maximum velocity, for comparison with previous work on narrowband vibrations in linear shear flow. The flow is found to excite the structure at a number of different locations under a condition of wake–body synchronization, or lock-in. Broadband responses are associated with a distributed occurrence of the lock-in condition along the span, as opposed to the localized lock-in regions limited to the high inflow velocity zone, reported for narrowband vibrations in sheared current. Despite the instantaneously multi-frequency nature of broadband responses, the lock-in phenomenon remains a locally mono-frequency event, since the vortex formation is generally synchronized with a single vibration frequency at a given location. The spanwise distribution of the excitation zones induces travelling structural waves moving in both directions; this contrasts with the narrowband case where the direction of propagation toward decreasing inflow velocity is preferred. A generalization of the mechanism of phase-locking between the in-line and cross-flow responses is proposed for broadband VIVs under the lock-in condition. A spanwise drift of the in-line/cross-flow phase difference is identified for the high-wavenumber vibration components; this drift is related to the strong travelling wave character of the corresponding structural waves.
The effect of velocity shear on dynamo action due to rotating convection
Authors: Hughes D. W. , Proctor M. R. E.
Published: February 2013

Recent numerical simulations of dynamo action resulting from rotating convection have revealed some serious problems in applying the standard picture of mean field electrodynamics at high values of the magnetic Reynolds number, and have thereby underlined the difficulties in large-scale magnetic field generation in this regime. Here we consider kinematic dynamo processes in a rotating convective layer of Boussinesq fluid with the additional influence of a large-scale horizontal velocity shear. Incorporating the shear flow enhances the dynamo growth rate and also leads to the generation of significant magnetic fields on large scales. By the technique of spectral filtering, we analyse the modes in the velocity that are principally responsible for dynamo action, and show that the magnetic field resulting from the full flow relies crucially on a range of scales in the velocity field. Filtering the flow to provide a true separation of scales between the shear and the convective flow also leads to dynamo action; however, the magnetic field in this case has a very different structure from that generated by the full velocity field. We also show that the nature of the dynamo action is broadly similar irrespective of whether the flow in the absence of shear can support dynamo action.
Convectons in a rotating fluid layer
Authors: Beaume Cédric , Bergeon Alain , Kao Hsien-Ching , Knobloch Edgar
Published: February 2013

Two-dimensional convection in a plane layer bounded by stress-free perfectly conducting horizontal boundaries and rotating uniformly about the vertical is considered. Time-independent spatially localized structures, called convectons, of even and odd parity are computed. The convectons are embedded within a self-generated shear layer with a compensating shear flow outside the structure. These states are organized within a bifurcation structure called slanted snaking and may be present even when periodic convection sets in supercritically. These interesting properties are traced to the presence of a conserved quantity and hence to the use of stress-free boundary conditions.
A new equation describing travelling water waves
Authors: Oliveras Katie , Vasan Vishal
Published: February 2013

A new single equation for the surface elevation of a travelling water wave in an incompressible, inviscid, irrotational fluid is derived. This new equation is derived without approximation from Euler’s equations, valid for both a one- and two-dimensional travelling-wave surface. We show that this new formulation can be used to efficiently derive higher-order Stokes-wave approximations, and pose that this new formulation provides a useful framework for further investigation of travelling water waves.
Hybrid Eulerian–Lagrangian simulations for polymer–turbulence interactions
Authors: Watanabe Takeshi , Gotoh Toshiyuki
Published: February 2013

The effects of polymer additives on decaying isotropic turbulence are numerically investigated using a hybrid approach consisting of Brownian dynamics simulations for an enormous number of dumbbells (of the order of 10 billion,$O(1{0}^{10} )$) and direct numerical simulations of turbulence making full use of large-scale parallel computations. Reduction of the energy dissipation rate and modification of the kinetic energy spectrum in the dissipation range scale were observed when the reaction term due to the polymer additives was incorporated into the equation of motion for the solvent fluid. An increase in the polymer concentration or Weissenberg number${W}_{i} $yielded significant modifications of the turbulence statistics at small scales, such as a suppression of the local energy dissipation fluctuations. A power-law decay of the kinetic energy spectrum$E(k, t)\sim {k}^{- 4. 7} $was observed in the wavenumber range below the Kolmogorov length scale when${W}_{i} = 25$. The generation of intense vortices was suppressed by the polymer additives, consistent with previous studies using the constitutive equations. The field structures of the trace of the polymer stress depended on the intensity of its fluctuation: sheet-like structures were observed for the intermediate intensity region and filamentary structures were observed for the intense region. The results obtained with few polymers and large replicas could approximate those with many polymers and smaller replicas as far as the large-scale statistics were concerned.
Minimal models for precipitating turbulent convection
Authors: Hernandez-Duenas Gerardo , Majda Andrew J. , Smith Leslie M. , Stechmann Samuel N.
Published: February 2013

Simulations of precipitating convection would typically use a non-Boussinesq dynamical core such as the anelastic equations, and would incorporate water substance in all of its phases: vapour, liquid and ice. Furthermore, the liquid water phase would be separated into cloud water (small droplets suspended in air) and rain water (larger droplets that fall). Depending on environmental conditions, the moist convection may organize itself on multiple length and time scales. Here we investigate the question, what is the minimal representation of water substance and dynamics that still reproduces the basic regimes of turbulent convective organization? The simplified models investigated here use a Boussinesq atmosphere with bulk cloud physics involving equations for water vapour and rain water only. As a first test of the minimal models, we investigate organization or lack thereof on relatively small length scales of approximately 100 km and time scales of a few days. It is demonstrated that the minimal models produce either unorganized (‘scattered’) or organized convection in appropriate environmental conditions, depending on the environmental wind shear. For the case of organized convection, the models qualitatively capture features of propagating squall lines that are observed in nature and in more comprehensive cloud resolving models, such as tilted rain water profiles, low-altitude cold pools and propagation speed corresponding to the maximum of the horizontally averaged, horizontal velocity.
Mineral Waters, Electricity, and Hemlock: Devising Therapeutics for Children in Eighteenth-Century Institutions
Authors: MATHISEN ASHLEY
Published: February 2013

The development of paediatric medicine as a formal field of medical specialisation is usually traced to the mid-nineteenth century at the earliest. While it is true that formal specialisation in children’s medicine was not, on the whole, typical for eighteenth-century medical practitioners, many displayed a deep and lasting interest in the diseases of children, and were consequently eager to develop therapeutic practices which could be targeted at infants and children. This led to a variety of attempts at innovation, many of which benefitted from the co-operation of, and opportunities afforded by, institutions. By examining the efforts of several medical practitioners at the London Foundling Hospital and at the Dispensary for the Infant Poor, this article explores how eighteenth-century medical practitioners used their affiliations with institutions to address the problems of devising or adapting therapeutic practices and treatments for children. In tailoring medical practice to suit children and, more specifically, in using institutions to do so, medical practitioners were demonstrating that child patients required special consideration, that children’s diseases could be managed medically and with the benefit of new approaches and methods, and that children’s health, as a whole, was the province of medical practitioners.
‘For the Convenience and Comfort of the Persons Employed by them’: The Lowell Corporation Hospital, 1840–1930
Authors: Greenlees Janet
Published: February 2013

The first industrial hospital in America opened in 1840 in Lowell, Massachusetts. The Lowell Corporation Hospital was sponsored by the town’s textile employers for ninety years. This article analyses the contextual complications surrounding the employers’ sustained funding of the hospital. Motivations for sustained sponsorship included paternalism, clinical excellence, business custom, the labour situation in Lowell, civic duty and the political advantages of paternalism. By analysing the changing local context of the hospital, this article argues that a broader, more integrated approach to healthcare histories and institution histories is needed if we are to fully understand the myriad of healthcare providers and their local and national importance.
‘I’ve Never Found Doctors to be a Difficult Bunch’: Doctors, Managers and NHS Reorganisations in Manchester and Salford, 1948–2007
Authors: Snow Stephanie J.
Published: February 2013

Since 1974 the National Health Service (NHS) has been subject to successive reorganisations which have shaped and reshaped patterns of administration, clinical care and services. This paper uses two sources of oral evidence: a Witness Seminar with a group of administrators who attended the NHS National Administrators’ Training Scheme in the late 1950s and a collection of interviews with doctors and managers who have played key roles in the health services of Manchester and Salford between 1974 and 2007. It surveys the day-to-day interactions between doctors and administrators/managers in hospital settings and analyses what these reveal about relationships within the broader context of shifting organisational structures and management styles. It suggests that the evidence challenges the historical stereotyping of the two groups and that strong working relationships have been determined as much by the values of respect and association as by changes to structures or management styles.
Road Traffic Injuries: Social Change and Development
Authors: Borowy Iris
Published: February 2013

In the course of the twentieth century road traffic injuries (RTIs) became a major public health burden. RTI deaths first increased in high-income countries and declined after the 1970s, and they soared in low- and middle-income countries from the 1980s onwards. As motorisation took off in North America and then spread to Europe and to the rest of the world discussions on RTIs have reflected and influenced international interpretations of the costs and benefits of ‘development’, as conventionally understood. Using discourse analysis, this paper explores how RTIs have been constructed in ways that have served regional and global development agendas and how ‘development’ has been (re-)negotiated through the discourse of RTIs and vice versa. For this purpose, this paper analyses a selection of key publications of organisations in charge of international health or transport and places them in the context of (a) the surrounding scientific discussion of the period and (b) of relevant data regarding RTI mortality, development funding, and road and other transport infrastructure. Findings suggest that constructions of RTIs have shifted from being a necessary price to be paid for development to being a sign of development at an early stage or of an insufficiently coordinated development. In recent years, RTI discussions have raised questions about development being misdirected and in need of fundamental rethinking. At present, discussions are believed to be at a crossroads between different evaluations of developmental conceptualisations for the future.
Modulation of platelet aggregation-related eicosanoid production by dietary F-fucoidan from brown algaLaminaria japonicain human subjects
Authors: Ren Rendong , Azuma Yosuke , Ojima Takao , Hashimoto Takashi , Mizuno Masashi , Nishitani Yosuke , Yoshida Masaru , Azuma Takeshi , Kanazawa Kazuki
Published: February 2013

Laminaria japonicais traditionally eaten in Japan as a beneficial food for thrombosis. The alga contains two specific ingredients, a xanthophyll fucoxanthin (FX) and a polysaccharide, F-fucoidan (FD). The aim of the present study was to investigate whether FX or FD exhibited anti-thrombotic effects. For this purpose, three types of capsules, containing 1 mg FX, 400 mg fucoidan, and both, were prepared from the alga and administered to volunteers for 5 weeks. The dose of FD or FD+FX significantly shortened lysis time (LT) of the thrombus measured by a global thrombosis test in the blood, but FX did not. Examining the mechanism, dietary FD increased H2O2and the secretion of prostacyclin (PGI2), a potent inhibitor of platelet aggregation, in the blood, although FD was under the detection limit in the blood, determining with its monoclonal antibody. Furthermore, in mouse experiments, dietary FD was totally excreted into the faeces and was not incorporated into the blood. We then employed a co-culture system of a Caco-2 cell monolayer with fresh human blood. The addition of FD to Caco-2 cells stimulated the expression of NADPH oxidase 1 (NOX1) and dual oxidase 2 (DUOX2) mRNA and secreted H2O2onto the blood side accompanied by a significant increase in serum PGI2production. These effects were invalidated by the combined addition of FD with its monoclonal antibody. The results suggested that dietary FD stimulated the expression of H2O2-producing enzymes in intestinal epithelial cells and released H2O2into the blood, which played a signalling role to increase PGI2production and then shortened LT for thrombi.
ATTITUDES TO THE DISPLACEMENT OF CULTURAL PROPERTY IN THE WARS OF THE FRENCH REVOLUTION AND NAPOLEON
Authors: GILKS DAVID
Published: February 2013

The French state expropriated an enormous quantity of cultural property from across Europe during the Wars of the Revolution and Napoleon, but much was returned in 1815 after the fall of the Empire. This article examines contemporary attitudes to the displacement of works of art, antiquities, scientific specimens, and rare books. The seizures were controversial: since they occurred at a time when plundering the vanquished was already considered questionable behaviour, they attracted opposition and needed to be justified. The article identifies the resulting repertoire of attitudes, arguing that this repertoire evolved with changing circumstances and was more varied than hitherto maintained. By situating this repertoire in a larger historical context, the article also reassesses the extent to which attitudes were derivative and innovative. It contends that the disputation as a whole did not amount to a decisive rupture in the treatment of foreign cultural property during wartime, but that it was nevertheless remarkable in two respects: concepts from hitherto unrelated subjects were applied to considerations about cultural property; and the perceived conditions under which cultural property could be legitimately transferred were revised.
FRENCH PRISONERS OF WAR, CONFLICTS OF HONOUR, AND SOCIAL INVERSIONS IN ENGLAND, 1744–1783
Authors: MORIEUX RENAUD
Published: February 2013

During the wars of the eighteenth century, French prisoners on parole in Britain were placed in a paradoxical situation of captives with privileges. Instead of studying these men as if they dwelt in a world apart, this article focuses on captivity zones as a social laboratory, where people of different status would socialize. These spaces accordingly provide a lens through which to glimpse the repercussions of international conflicts at the level of local communities. The disputes which opposed these captives to the English population, which were the object of letters of complaints sent by the French prisoners to the authorities, shed light on the normative and moral resources which were used by eighteenth-century Englishmen and Frenchmen to legitimize themselves in situations of social conflict. As a configuration characterized by shifting social relations, the parole zone brought together local, national, and international issues, intertwined primarily in the rhetoric of honour. In these incidents, there was no systematic alignment of class and national discourses and actions, while the precise standing of these Frenchmen on the social ladder was constantly challenged and debated. The resulting quarrels therefore reveal a series of social inversions: dominant groups in France were in many respects dominated in England. Rather than being a mere reflection of pre-existing social hierarchies, such micro-incidents reinvented them.
Corporate Criminal Responsibility: A Comparative Analysis
Authors: Nwafor Anthony O
Published: February 2013

This article focuses on the extent of a company's responsibility for the criminal conduct of its employees. It considers the initial reluctance of common law courts to hold corporations criminally responsible for offences requiring mens rea, a mental element not found in artificial persons. The courts overcame this initial difficulty with recourse to the identification doctrine, which seeks to attribute to a company the fault of certain of its officers. However, the restrictiveness and inconsistencies embodied in the various judicial statements of that doctrine precipitated recourse in some jurisdictions to civil law concepts, such as respondeat superior, vicarious liability and even strict liability, to found corporate criminal responsibility. The need to streamline the scope of, if not enhance, corporate criminal liability, has engendered statutory reforms in some jurisdictions. The article considers reforms in Australia, the UK, Canada and the USA, in comparison with the situation in South Africa and Lesotho.
Effects of chronic noise exposure on speech-in-noise perception in the presence of normal audiometry
Authors: Hope A J , Luxon L M , Bamiou D-E
Published: February 2013

Objective:

To assess auditory processing in noise-exposed subjects with normal audiograms and compare the findings with those of non-noise-exposed normal controls.

Methods:

Ten noise-exposed Royal Air Force aircrew pilots were compared with 10 Royal Air Force administrators who had no history of noise exposure. Participants were matched in terms of age and sex. The subjects were assessed in terms of: pure tone audiometry, transient evoked otoacoustic emissions, suppression of transient evoked otoacoustic emissions in contralateral noise and auditory processing task performance (i.e. masking, frequency discrimination, auditory attention and speech-in-noise).

Results:

All subjects had normal pure tone audiometry and transient evoked otoacoustic emissions amplitudes in both ears. The noise-exposed aircrew had similar pure tone audiometry thresholds to controls, but right ear transient evoked otoacoustic emissions were larger and speech-in-noise thresholds were elevated in the noise-exposed subjects compared to controls.

Conclusion:

The finding of poorer speech-in-noise perception may reflect noise-related impairment of auditory processing in retrocochlear pathways. Audiometry may not detect early, significant noise-induced hearing impairment.
Great Ormond Street Hospital treatment guidelines for use of propranolol in infantile isolated subglottic haemangioma
Authors: Bajaj Y , Kapoor K , Ifeacho S , Jephson C G , Albert D M , Harper J I , Hartley B E
Published: February 2013

Objective:

Treatment options for large subglottic haemangioma include steroids, laser ablation, open excision, tracheostomy and, more recently, propranolol. This article aims to present the Great Ormond Street Hospital guidelines for using propranolol to treat infantile isolated subglottic haemangioma by ENT surgeons.

Methods:

The vascular malformations multidisciplinary team at Great Ormond Street Hospital has developed guidelines for treating infantile haemangioma with propranolol.

Results:

The Great Ormond Street Hospital guidelines for propranolol treatment for infantile subglottic haemangioma include investigation, treatment and follow up. Propranolol is started at 1 mg/kg/day divided into three doses, increasing to 2 mg/kg/day one week later. On starting propranolol and when increasing the dose, the pulse rate and blood pressure must be checked every 30 minutes for the first 2 hours. Lesion response to treatment is assessed via serial endoscopy.

Conclusion:

Recent reports of dramatic responses to oral propranolol in children with haemangioma and acute airway obstruction have led to increased use. We advocate caution, and have developed guidelines (including pre-treatment investigation and monitoring) to improve treatment safety. Propranolol may in time prove to be the best medical treatment for subglottic haemangioma, but at present is considered to be still under evaluation.
From Buddhist Icons to National Antiquities: Cultural Nationalism and Colonial Knowledge in the Making of Thailand's History of Art
Authors: PELEGGI MAURIZIO
Published: February 2013

In the mid 1920s Prince Damrong Rajanubhab and George Coedès jointly formulated the stylistic classification of Thailand's antiquities that was employed to reorganize the collection of the Bangkok Museum and has since acquired canonical status. The reorganization of the Bangkok Museum as a ‘national’ institution in the final years of royal absolutism responded to increasing international interest in the history and ancient art of Southeast Asia, but represented also the culmination of several decades of local antiquarian pursuits. This paper traces the origins of the art history of Thailand to the intellectual and ideological context of the turn of the twentieth century and examines its parallelism to colonial projects of knowledge that postulated a close linkage between race, ancestral territory and nationhood.
Asian Borderlands and the Legal Protection of Traditional Knowledge and Traditional Cultural Expressions
Authors: ANTONS CHRISTOPH
Published: February 2013

Traditional knowledge related to biodiversity, agriculture, medicine and artistic expressions has recently attracted much interest amongst policy makers, legal academics and social scientists. Several United Nations organizations, such as the World Intellectual Property Organization (WIPO) and theConvention on Biological Diversityunder the United Nations Environmental Programme (UNEP), have been working on international models for the protection of such knowledge held by local and indigenous communities. Relevant national, regional or provincial level legislation comes in the form of intellectual property laws and laws related to health, heritage or environmental protection. In practice, however, it has proven difficult to agree on definitions of the subject matter, to delineate local communities and territories holding the knowledge, and to clearly identify the subjects and beneficiaries of the protection. In fact, claims to ‘cultural property’ and heritage have led to conflicts and tensions between communities, regions and nations. This paper will use Southeast Asian examples and case studies to show the importance of concepts such asZomia, ‘regions of refuge’ andmandalaas well as ‘borderlands’ studies to avoid essentialized notions of communities and cultures in order to develop a nuanced understanding of the difficulties for national and international lawmaking in this field. It will also develop a few suggestions on how conflicts and tensions could be avoided or ameliorated.
Chinese film exhibition in Occupied Manila (1942–1945)
Authors: TAYLOR JEREMY E.
Published: February 2013

This paper explores the nature of film exhibition amongst the Chinese community in Manila during the Japanese Occupation of that city. Based on advertisements and film listings published in the Chinese-language press of the day (as well as on pre-war records concerning commercial Chinese entertainment in the Philippines), it explores the continuities in film exhibition practice undertaken by various theatre operators within the Binondo area of Manila both before, during, and after the war. The paper suggests not only that such practices represented a quite different trajectory from that experienced in other parts of Occupied Manila, but also that a more thorough exploration of the Manila Chinese during wartime—one which goes beyond questions of mere collaboration and/or resistance—will encourage us to question some of the assumptions that underpin recent scholarship about this community.
First molecular characterization ofCryptosporidiumin Yemen
Authors: ALYOUSEFI N. A. , MAHDY M. A. K. , LIM Y. A. L. , XIAO L. , MAHMUD R.
Published: February 2013

Cryptosporidiumis a protozoan parasite of humans and animals and has a worldwide distribution. The parasite has a unique epidemiology in Middle Eastern countries where the IId subtype family ofCryptosporidium parvumdominates. However, there has been no information onCryptosporidiumspecies in Yemen. Thus, this study was conducted in Yemen to examine the distribution ofCryptosporidiumspecies and subtype families. Fecal samples were collected from 335 patients who attended hospitals in Sana'a city.Cryptosporidiumspecies were determined by PCR and sequence analysis of the 18 s rRNA gene.Cryptosporidium parvumandC. hominissubtypes were identified based on sequence analysis of the 60 kDa glycoprotein (gp60) gene. Out of 335 samples, 33 (9·9%) were positive forCryptosporidium. Of them, 97% were identified asC. parvumwhilst 1 case (3%) was caused byC. hominis. All 7C. parvumisolates subtyped belonged to the IIaA15G2R1 subtype. The common occurrence of the zoonotic IIa subtype family ofC. parvumhighlights the potential occurrence of zoonotic transmission of cryptosporidiosis in Yemen. However, this postulation needs confirmation with future molecular epidemiological studies of cryptosporidiosis in both humans and animals in Yemen.
Characterization of the novelTrypanosoma bruceiinosine 5′-monophosphate dehydrogenase
Authors: BESSHO TOMOAKI , MORII SHOKO , KUSUMOTO TOSHIHIDE , SHINOHARA TAKAHIRO , NODA MASANORI , UCHIYAMA SUSUMU , SHUTO SATOSHI , NISHIMURA SHIGENORI , DJIKENG APPOLINAIRE , DUSZENKO MICHAEL , MARTIN SAMUEL K. , INUI TAKASHI , KUBATA KILUNGA B.
Published: February 2013

There is an alarming rate of human African trypanosomiasis recrudescence in many parts of sub-Saharan Africa. Yet, the disease has no successful chemotherapy.Trypanosomalacks the enzymatic machinery for thede novosynthesis of purine nucleotides, and is critically dependent on salvage mechanisms. Inosine 5′-monophosphate dehydrogenase (IMPDH) is responsible for the rate-limiting step in guanine nucleotide metabolism. Here, we characterize recombinantTrypanosoma bruceiIMPDH (TbIMPDH) to investigate the enzymatic differences between TbIMPDH and host IMPDH. Size-exclusion chromatography and analytical ultracentrifugation sedimentation velocity experiments reveal that TbIMPDH forms a heptamer, different from type 1 and 2 mammalian tetrameric IMPDHs. Kinetic analysis reveals calculatedKmvalues of 30 and 1300 μmfor IMP and NAD, respectively. The obtainedKmvalue of TbIMPDH for NAD is approximately 20–200-fold higher than that of mammalian enzymes and indicative of a different NAD binding mode between trypanosomal and mammalian IMPDHs. Inhibition studies showKivalues of 3·2 μm, 21 nM and 3·3 nM for ribavirin 5′-monophosphate, mycophenolic acid and mizoribine 5′-monophosphate, respectively. Our results show that TbIMPDH is different from its mammalian counterpart and thus may be a good target for further studies on anti-trypanosomal drugs.
Role of kairomones in host location of the pennellid copepod parasite, Lernaeocera branchialis (L. 1767)
Authors: BROOKER A. J. , SHINN A. P. , SOUISSI S. , BRON J. E.
Published: February 2013

The life cycle of the parasitic copepod Lernaeocera branchialis involves 2 hosts, typically a pleuronectiform host upon which development of larvae and mating of adults occurs and a subsequent gadoid host, upon which the adult female feeds and reproduces. Both the copepodid and adult female stages must therefore locate and identify a suitable host to continue the life cycle. Several mechanisms are potentially involved in locating a host and ensuring its suitability for infection. These may include mechano-reception to detect host movement and chemo-reception to recognize host-associated chemical cues, or kairomones. The aim of this study was to identify the role of kairomones in host location by adult L. branchialis, by analysing their behaviour in response to fish-derived chemicals. Experiments demonstrated that water conditioned by immersion of whiting, Merlangius merlangus, elicited host-seeking behaviour in L. branchialis, whereas cod- (Gadus morhua) conditioned water did not. Lernaeocera branchialis are considered a genetically homogeneous population infecting a range of gadoids. However, their differential response to whiting- and cod-derived chemicals in this study suggests that either there are genetically determined subspecies of L. branchialis or there is some form of environmental pre-conditioning that allows the parasite to preferentially recognize the host species from which it originated.
Genetic and environmental risk factors in males for self-report externalizing traits in mid-adolescence and criminal behavior through young adulthood
Authors: Kendler K. S. , Patrick C. J. , Larsson H. , Gardner C. O. , Lichtenstein P.
Published: February 2013

Background

Externalizing traits or behaviors are typically assessed by self-report scales or criminal records. Few genetically informative studies have used both methods to determine whether they assess the same genetic or environmental risk factors.

Method

We examined 442 male Swedish twin pairs with self-reported externalizing behaviors at age 16–17 years [externalizing traits (EXT), self-reported delinquency (SRD), impulsivity (IMP), grandiosity (GRD) and callousness (CLS)] and criminal behavior (CB) from the National Suspect Registry from age 13 to 25 years. Multivariate structural equation modeling was conducted with Mx.

Results

The best-fit model contained one genetic, one shared environmental and two non-shared environmental common factors, and variable specific genetic and non-shared environmental factors. The risk for CB was influenced substantially by both genetic (a2 = 0.48) and familial–environmental factors (c2 = 0.22). About one-third of the genetic risk for CB but all of the shared environmental risk was indexed by the self-report measures. The degree to which the individual measures reflected genetic versus familial–environmental risks for CB varied widely. GRD and CLS were correlated with CB mainly through common genetic risk factors. SRD and CB covaried largely because of shared familial–environmental factors. For EXT and IMP, observed correlations with CB resulted in about equal parts from shared genetic and shared familial–environmental factors.

Conclusions

In adolescence, measures of grandiose and callous temperament best tap the genetic liability to CB. Measures of antisocial behaviors better index familial–environmental risks for CB. A substantial proportion of the genetic risk to CB was not well reflected in any of the self-report measures.
From mutualism to moral transcendence
Authors: Atran Scott
Published: February 2013

Baumard et al. attribute morality to a naturally selected propensity to share costs and benefits of cooperation fairly. But how does mundane mutualism relate to transcendent notions of morality critical to creating cultures and civilizations? Humans often make their greatest exertions for an idea they form of their group. Primary social identity is bounded by sacred values, which drive individuals to promote their group through non-rational commitment to actions independently of likely risks and rewards.
“Fair” outcomes without morality in cleaner wrasse mutualism
Authors: Bshary Redouan , Raihani Nichola
Published: February 2013

Baumard et al. propose a functional explanation for the evolution of a sense of fairness in humans: Fairness preferences are advantageous in an environment where individuals are in strong competition to be chosen for social interactions. Such conditions also exist in nonhuman animals. Therefore, it remains unclear why fairness (equated with morality) appears to be properly present only in humans.
Heterogeneity in fairness views: A challenge to the mutualistic approach?
Authors: Cappelen Alexander W. , Tungodden Bertil
Published: February 2013

This commentary argues that the observed heterogeneity in fairness views, documented in many economic experiments, poses a challenge to the partner choice theory developed by Baumard et al. It also discusses the extent to which their theory can explain how people consider inequalities due to pure luck.
A strange(r) analysis of morality: A consideration of relational context and the broader literature is needed
Authors: Clark Margaret S. , Boothby Erica
Published: February 2013

Baumard et al.'s definition of morality is narrow and their review of empirical work on human cooperation is limited, focusing only on economic games, almost always involving strangers. We suggest that theorizing about mutualisms will benefit from considering extant empirical behavioral research far more broadly and especially from taking relational context into account.
Does market competition explain fairness?
Authors: DeScioli Peter
Published: February 2013

The target article by Baumard et al. uses their previous model of bargaining with outside options to explain fairness and other features of human sociality. This theory implies that fairness judgments are determined by supply and demand but humans often perceive prices (divisions of surplus) in competitive markets to be unfair.
Evidence for partner choice in toddlers: Considering the breadth of other-oriented behaviours
Authors: Dunfield Kristen A. , Kuhlmeier Valerie A.
Published: February 2013

When do humans become moral beings? This commentary draws on developmental psychology theory to expand the understanding of early moral behaviours. We argue that by looking at a broader range of other-oriented acts than what has been considered by Baumard et al., we can find support for the mutualistic approach to morality even in early instances of other-oriented behaviours.
Mutualism is only a part of human morality
Authors: Gintis Herbert
Published: February 2013

Baumard et al. mischaracterize our model of individual and social choice behavior. We model individuals who maximize preferences given their beliefs, and subject to their informational and material constraints (Fehr & Gintis 2007). Individuals thus must make trade-offs among self-regarding, other-regarding, and character virtue goals. Two genetic predispositions are particularly crucial. The first isstrong reciprocity. The second is the capacity tointernalize normsthrough the socialization process. Our model includes the authors' model as a subset.
Beyond economic games: A mutualistic approach to the rest of moral life
Authors: Graham Jesse
Published: February 2013

Mutualism provides a compelling account of the fairness intuitions on display in economic games. However, it is not yet clear how well the approach holds up as an explanation of all human morality. The theory needs to be tested outside the methodological neighborhood it was born in; such testing has the potential to greatly improve our understanding of morality in general.