bluuebunny/crossref_metadata_2025 huggingface dataset:
Análise de Arquiteturas para Processamento de Imagens
Authors: Mendes Celso Luiz , Câmara Neto Gilberto , Mura José Claudio , Garrido Juan Carlos Pinto de , Souza Ricardo Cartaxo Modesto de
Published: March 2023

Após uma breve introdução sobre as atividades de Processamento de Imagens no INPE, são mostradas as características principais da familia de sistemas SITIM, seguindo-se uma apresentação dos tipos de procedimentos mais utilizados em Processamento de Imagens. São discutidas algumas opções jã testadas para aumento de desempenho do sistema, através do uso de placas aceleradoras, e ao final são apresentadas as perspectivas de desenvolvimento futuro, tanto na área de placas aceleradoras como sistemas baseados em arquitetura paralela, associados a unidades de armazenamento de imagens avançadas.
Uma Experiência de Especificação Formal de Sistemas Multiprocessadores por Redes de Petri
Authors: Aguilar M. M. Fiallos
Published: March 2023

Este artigo descreve uma experiência de utilização de Redes de Petri na especificação formal de Sistemas Multiprocessadores. - São introduzidos alguns conceitos básicos da teoria de Redes de Petri utilizadas na especificação de um sistema multimicroprocessador específico |FIAL 85|.
Processadores Bipartidos Aspectos de Projeto
Authors: França Felipe Maia Galvão , Fernandes Edil Severiano Tavares
Published: March 2023

As motivações e contextos do aparecimento de processadores bipartidos devem ser esclarecidos. A detecção de paralelismo potencial ao nível convencional de instruções durante a execução de uma tarefa sequencial permite que se dobre o alcance máximo do desempenho. RISC e VLSI caracterizam o meio-ambiente de dois exemplos que serão vistos aqui.
Análise de Desempenho e Implementação de Arquiteturas Paralelas
Authors: Costa Luciano da Fontoura , Travieso Gonzalo , Slaets Jan Frans Willem
Published: March 2023

Este trabalho analisa três formas de implementação em "hardware" para o processamento de uma mesma operação indivisível sobre diversos valores considerando-se a eficiência na utilização das memórias, que é um indicativo da velocidade total de processamento. Entre as arquiteturas analisadas, uma consiste de um único processador, outra é o processador de "array" propriamente dito (veja, por exemplo, pg. 120 da referência [1]), e uma outra mostra-se a melhor das arquiteturas aqui analisadas quando algumas condições forem obedecidas.
Proyecto ARPAS: Computadora com arquitectura paralela de alta velocidad
Authors: Cingolani Horacio , Ferrán Edgardo , Ferrero Armando , Nicolás Juan J. , Praga Néstor , Perazzo Roberto , Reich Silvia , Ridner Alberto , Sinderman Jorge
Published: March 2023

Se describe el Proyecto ARPAS, que se ha comenzado recientemente en la República Argentina, con el objeto de construir una computadora con arquitectura paralela tipo SIMD.
Etude et Conception de la Machine de Communication du Coprocesseur Felin
Authors: Cosnard Paul M. , Duprat J. , Guyot A. , Hochet B. , Muller J. M. , Ouaouicha H. , Zysman E.
Published: March 2023

Nous décrirons l' architecture VLSI de la machine de communication d' un calculateur d' expressions arithmétiques (composées de fonctions élémentaires en virgule flottante) appelé FELIN (Fonctions Elémentaires Intégrées). Les principaux' attraits de l'architecture de la machine de communication sont la régularité, la paramétrisation et la génération automatique du dessin des masques, comme c'était le cas pour la machine á calcul (partie contróle et partie opérative). Le chip final est dessiné en technologie CMOS deux couches d'aluminium. Le travail a ete soutenu en partie par le GRECO C3 et le GCIS du CNRS français.
Relatório do Projeto ETHOS
Authors: Lucena Carlos José Pereira de , Takahashi Tadao
Published: March 2023

Este artigo não possui resumo.
Introdução ao Processamento Paralelo
Authors: Navaux Philippe O. A.
Published: March 2023

O presente trabalho apresenta a área de Processamento Paralelo nos seus principais tópicos desde as arquiteturas, linguagens, compiladores, até os algoritmos. São apresentadas classificações, terminologia empregada e aplicações, objetivando ressaltar os principais problemas que ainda precisam ser solucionados para um maior e melhor uso destas máquinas.
LSI-S0.01 - Um Sistema Operacional Multiprocessador
Authors: Midorikawa Edson Toshimi , Knop Felipe , Branco Roberto Diniz , Yu Wang Kuei
Published: March 2023

Es te trabalho descreve o sistema operacional multiprocessador LSl-S0.01, compatível com o UNIX System V.3, em desenvolvimento no LSI-USP. Este sistema fornece meios para a obtenção de processamento paralelo através da utilização dos recursos da arquitetura multiprocessadora da máquina. Descrevem-se as principais características do sistema, tais como, seu sistema de arquivos, memória virtual e aquelas referentes a processamento paralelo e multiprocessamento.
Processador Especializado para Sistemas VME
Authors: Zuffo M. K. , L. Netto M. , Lopes R. D.
Published: March 2023

O Processador Especializado (PE), destina-se a processamento numérico. Ele se constitui num dadoduto ("pipeline") onde cada um dos estágios é denominado Módulo de Processamento Especializado (MPE), o PE comporta um número variável de MPEs, capacitando o sistema a se configurar modularmente de acordo com os requisitos de performance exigidos, e estando sua gerência a cargo do processador central do sistema ao qual seja incorporado. Duas implementações do MPE são apresentadas.
Padronização de Serviços de Sincronismo e de Comunicação entre Tarefas para Arquiteturas Distribuídas
Authors: Motta J. , Ramos J.
Published: March 2023

Este trabalho descreve as vantagens decorrentes da padronização das primitivas de sincronismo e comunicação entre tarefas para arquiteturas distribuídas. Exemplos práticos mostram a utilização da metodologia proposta.
Uma Nota sobre Solução Paralela de Sistemas Lineares Esparsos
Authors: Terry L. A. , Teixeira M. J. , Roméro S. P.
Published: March 2023

A solução de um sistema de equações lineares esparso é central para inúmeras aplicações utilizadas no planejamento e operação de sistemas elétricos. Este artigo aborda o problema da solução direta de sistemas lineares esparsos em arquiteturas baseadas em memória compartilhada. O grafo de dependências entre as tarefas envolvidas na solução é apresentado e analisado utilizando exemplos do sistema elétrico brasileiro. Uma implementação paralela, destinada a uma avaliação preliminar dos algoritmos e determinação dos limites do "hardware" disponível no Cepel, também é descrita e os seus resultados são apresentados. Desenvolvimentos destinados a melhorar o desempenho dos algoritmos são sugeridos.
Avaliação de Desempenho de um Sistema Multiprocessador
Authors: Zelenovsky Ricardo
Published: March 2023

É proposto o modelamento de um sistema multiprocessador. É feita análise de seu desempenho com relação a decomposição e alocação de subproblemas aos processadores, tamanho do grão e eficiência do "cache". São estabelecidos critérios para adequar o sistema aos algoritmos de forma a maximizar o desempenho.
Computadores Paralelos com Arquitetura de Dutos
Authors: Sangiorgio Carlos Alberto
Published: March 2023

Computadores paralelos com arquitetura de dutos vem sendo cada vez mais utilizados pois representam uma opção atraente economicamente e de implementação rápida tanto a nível de hardware como de software. Partes do projeto do computador multiprocessador MS8701 (LSI-USP) são aqui apresentadas, sendo analisadas diferentes topologias de duto que foram objeto de estudo durante a definição da arquitetura do computador.
Avaliação de um Ambiente UNIX com Multiplos Processadores
Authors: Silva Gabriel P.
Published: March 2023

Este artigo apresenta uma avaliação de desempenho de um sistema multiprocessador, desenvolvido no NCE/UFRJ e denominado PEGASUS/PLURIX. O objetivo principal desta avaliação foi o de determinar o ganho obtido com o uso de múltiplos processadores em um ambiente do tipo UNIX. Um conjunto de programas portáteis foi utilizado para avaliar o sistema, permitindo uma comparação com resultados obtidos na execução destes programas em sistemas comerciais com ambiente UNIX.
Тасымалдауды басқарудың өңірлік орталығын құру
Authors: ТУРСЫМБЕКОВА З.Ж. , МЫРЗАГЕЛЬДИЕВ Р.А. , КУРБАНГАЛИЕВА Н.Б.
Published: March 2023

Структурно-технические изменения, происходящие в информационно-планируемой системе дороги, предусматривают два уровня планирования – дорожный и станционный. Основой функционирования АЦУП является ведение динамической модели поездного положения (ДМР) в реальном масштабе времени на базе информации автоматически снимаемой с СЖАТ.

Жолдың ақпараттық-жоспарланған жүйесінде болып жатқан құрылымдық-техникалық өзгерістер жоспарлаудың екі деңгейін – жол және станциялық жоспарлауды көздейді. АСУП жұмысының негізі қысымнан автоматты түрде алынатын ақпарат негізінде нақты уақыт шкаласында пойыз жағдайының динамикалық моделін (ДМР) жүргізу болып табылады

Structural and technical changes taking place in the information-planned system of the road provide for two levels of planning – road and station. The basis of the functioning of the automated control system is the maintenance of a dynamic model of the train position (DMR) in real time on the basis of information automatically removed from the compressed.
Екінші деңгейдегі банктің ресурстарын басқару
Authors: ТОКТАРХАНОВА Б.Т. , АБДИГАЛИЕВА Н.К.
Published: March 2023

Деятельность любого банка связана с работой различных активов, формирующихся из разных источников, это и активы, и пассивы. Сегодня в условиях экономических спадов особо остро стоит вопрос в управлении ресурсами банка второго уровня. Эффективное управление ресурсами банка позволяет акционерам получать прибыль, поддерживать текущий рейтинг, позволяет своевременно отвечать по своим обязательствам как перед другими банками, так и перед вкладчиками, которые разместили свои средства доверившись банку. Таким образом, пути совершенствования управления ресурсами банка являются одними из ключевых в структуре вопросов управления банка. Процесс создания ресурсной базы банка включает формирование акционерного капитала банка, привлечение депозитов, эмиссию кредитных ценных бумаг, а также поиск межбанковских кредитов на финансовых рынках. Способность банка привлекать депозиты и межбанковские кредиты является основным критерием признания банка другими участниками рынка.

Кез-келген банктің қызметі әртүрлі көздерден пайда болатын әртүрлі активтердің жұмысымен байланысты, бұл активтер де, міндеттемелер де. Бүгінгі таңда экономикалық құлдырау жағдайында екінші деңгейдегі банктің ресурстарын басқару мәселесі ерекше өткір тұр. Банк ресурстарын тиімді басқару акционерлерге пайда табуға, ағымдағы рейтингті сақтауға мүмкіндік береді, өз міндеттемелері бойынша басқа банктер алдында да, өз қаражатын банкке сеніп орналастырған салымшылар алдында да уақтылы жауап беруге мүмкіндік береді. Осылайша, банк ресурстарын басқаруды жетілдіру жолдары банкті басқару құрылымындағы негізгі мәселелердің бірі болып табылады. Банктің ресурстық базасын құру процесі Банктің акционерлік капиталын қалыптастыруды, депозиттерді тартуды, кредиттік бағалы қағаздар эмиссиясын, сондай-ақ қаржы нарықтарында банкаралық кредиттерді іздеуді қамтиды. Банктің депозиттер мен банкаралық несиелерді тарту қабілеті банкті нарықтың басқа қатысушылары ретінде танудың негізгі критерийі болып табылады.

The activity of any bank is connected with the work of various assets formed from different sources, these are both assets and liabilities. Today, in the conditions of economic downturns, the issue of managing the resources of a second-tier bank is particularly acute. Effective management of the bank's resources allows shareholders to make a profit, maintain the current rating, and timely meet their obligations both to other banks and to depositors who placed their funds trusting the bank. Thus, ways to improve the management of the bank's resources are among the key issues in the structure of the bank's management. The process of creating the bank's resource base includes the formation of the bank's share capital, the attraction of deposits, the issue of credit securities, as well as the search for interbank loans in financial markets. The bank's ability to attract deposits and interbank loans is the main criterion for the bank's recognition by other market participants.
Minuman Alkohol dan Agama : Studi pada Remaja di Surabaya
Authors: Gultom Ferdi , Fauzi Agus Machfud
Published: March 2023

Praktik konsumsi minuman alkohol memiliki makna tersendiri bagi para remaja. Sekalipun mereka memahami dan mempraktikan aturan agama mereka, namun para remaja memiliki pengetahuan tersendiri tentang minuman alkohol. Melalui pengetahuan mereka, seolah-olah dapat lolos dari aturan agama mereka. Penelitian ini bertujuan untuk mengidentifikasi pengalaman mengkonsumsi alkohol dan prakti keagamaan remaja di Surabaya. Penelitian menggunakan metode penelitian kualitatif dengan pendekatan teori interaksinonlisme simbolik untuk mengetahui presepsi tentang konsumis alkohol; mencari tahu tentang konsumsi alkohol, sehingga meloloskan diri dari aturan agama. Hasil penelitian ini menunjukan bahwa para remaja memiliki makna tentang konsumsi alkohol, seperti simbol kebahagiaan, penlampiasan, pencair suasana, rasa syukur, dan kebersamaan. Para remaja memberikan alasan bahwa konsumsi alkohol bukan urusan halal atau haramnya, selama tidak merugikan orang lain. Stigma masyarakat tentang alkohol adalah penyimpangan sosial dan agama dikarenakan digunakan secara rusuh, sehingga merugikan orang lain.
Dampak Learning Loss terhadap Psikososial Mahasiswa Saat dan Pasca Pandemi Covid-19
Authors: Kistoro Hanif Cahyo , Sihati Alfi , Habiba Iefone Shiflana , Difany Salsabila
Published: March 2023

Masa pendemi covid-19 mempunyai dampak luas disegala lini kehidupan. Salah satu efek yang sangat terasa dampaknya adalah aspek sosial. Tujuan Penelitian ini adalah untuk mengetahui dampak Learning Loss terhadap Psikososial Pelajar Pada saat dan pasca pendemi. Metode penelitian yang digunakan adalah metode penelitian kualitatif dengan pendekatan fenomenologi. Partisipan dalam penelitian ini adalah mahasiswa dari tiga perguruan tinggi islam di yogyakarta yang berjumlah 15 orang. pemilihan partisipan didasarkan pada kriteria yang sudah ditentukan secara purposive yaitu dari perguruan tinggi islam, mengalami masalah sosial secara khusus dan dapat diambil datanya. Teknik pengambilan data menggunakan wawancara secara mandalam sesuai dengan panduan instrument wawanacara yang sudah dibuat. Teknik analisis data melalui tiga tahap yaitu reduksi, penyajian data dan interpretasis data untuk mengambil kesimpulan. Temuan penelitian menghasilkan tiga kesimpulan. Pertama, dampak pendemi adalah hiangnya semangat belajar atau learning loss. Kedua, secara sosial dampak pendemi menimbulkan masalah psikososial yaitu cenderung menyendiri atau introvert. Ketiga, pasca pendemi sebagain besar mahasiswa sudah terlanjur nyaman dengan kondisinya saat pendemi sehingga mengalami kemalasan dan kejenuhan untuk melakukan aktifitas secara langsung.  Hasil penelitian ini masih mempunyai banyak celah kelemahan khususnya dalam pemilihan responden yang masih terbatas dan penggalian data serta analisisnya. Penelitian berikutnya akan sangat dibutuhkan dalam memberikan penguatan dan tambahan hasil yang lebih komprehensif
Blockchain and Distributed Ledger Technologies for IoT Security: A Survey paper
Authors: Suleiman Abdulrahman  , Maroning Useng
Published: March 2023

As the Internet of Things (IoT) continues to grow, the security concerns associated with this technology become increasingly important. Blockchain and Distributed Ledger Technologies (DLTs) are emerging as potential solutions for IoT security due to their decentralized and immutable nature. In this survey paper, we provide a comprehensive overview of the state-of-the-art research in the use of blockchain and DLTs for IoT security. We begin by introducing the basic concepts of blockchain and DLTs, followed by a discussion of their potential applications in IoT security. We then review the existing literature on the topic, including both academic and industrial research. We categorize the literature into different application areas, such as authentication, access control, and data integrity. Finally, we discuss the open research challenges and potential future directions for the use of blockchain and DLTs in IoT security. This survey paper provides a valuable resource for researchers and practitioners interested in understanding the current state-of-the-art research in this important area of IoT security.
First record of Pudeoniscidae Lemos de Castro, 1973 (Oniscidea) from Peru, with the description of a new genus and species
Authors: Ocampo-Maceda Ana Teresa , López-Orozco Carlos Mario , López-Tejeda Evaristo Luciano , Campos-Filho Ivanklin Soares
Published: March 2023

A new genus of Pudeoniscidae from Peru is described, Loretoniscus gen. nov., including a new species: Loretoniscus mashiriaensis gen. et sp. nov. The new genus is characterized by pereonite 1 epimera without dorsolateral furrows, pereonites 1 and 2 without ventral lobes, telson with distal portion covering uropod endopods, and pleopod 1–2 exopods with respiratory areas. This is the first record of the family Pudeoniscidae from Peru, considerably extending its distribution in the Neotropical region.
Mikrodenetleyici ile CanBus Haberleşme Ağı Üzerinden Veri Depolama Sistemi Uygulaması ve Performans Analizi
Authors: NUR Sercan Ozan , KARACA Ahmet
Published: March 2023

Otomotiv sektörü günümüz teknolojisinin en büyük fırsatlarından biridir. Otomobiller her zaman hayatımızın vazgeçilmez ekipmanlarının başındaki yerini koruyor. Bu sistemler hem mekanik hem de elektronik olarak çok büyük bir altyapıya ve tasarıma sahiptir. İnsanlar için ön planda olan bu ekipmanların gereksinimlerinde güvenlik önceliklidir. Bu nedenle her bir algılayıcının doğru çalışması ve sistem içerisinde birbirleriyle çok hassas bir şekilde iletişim kurmaları gerekir. Otomobillerdeki bu güvenli haberleşme CanBus haberleşme sistemi ile yapılmaktadır. Bu makalenin amacı, otomobillerdeki CanBus iletişim sistemleri üzerinden verilere erişmektir. Verilerin kaydedilmesi ve gerektiğinde erişilerek görselleştirilmesidir.

Bu makalede, arıza tespiti amacıyla otomobillerdeki CanBus üzerinden yayınlanan algılayıcı verilerinin gerçek zamanlı olarak okunması ve SD kart ortamında depolanması sağlanıştır. Ayrıca kaydedilen verilerin grafik ortama aktarılarak görselleştirilmesi sağlanmıştır.
Analysis on the tourist offer of the Vlora Region, from the viewpoint of tourism stakeholders
Authors: QOSJA Ermira , LIÇAJ Brunilda , MBRICA Ani , BRAHOLLI Aurela
Published: March 2023

The tourism industry is one of the vital sectors of the Albanian economy, an important contributor to the country’s GDP, investments and employment. During the last 10 years, through the investments, marketing and services provided, this sector has tried to offer tourism products which have significantly increased the number of visitors, both Albanians and foreigners, but still reflects many issues hindering its competitiveness in the region and the increase in profits. Given the problems that accompany this sector in relation to seasonality and the small number of days of stay of tourists, as well as concerning the objectives of the National Strategy for Sustainable Tourism Development 2019-20236 , this paper aims to analyse the tourist offer of the Vlora Region from the point of view of tourism stakeholders. The qualitative method is used to analyse the tourist offer of the Vlora Region, based on a questionnaire in the form of a semi-structured interview with private operators, public operators, donors and NGOs related to the sector, and training and educational institutions. The findings of the paper highlight not only the weaknesses and strengths of the offer, but also the opportunities and threats that need to be considered. In particular, they emphasize the need for cooperation and accountability in line with roles played in the sector.
Public policy at times of pandemic
Authors: XHAFERAJ Anjeza , BELLO Kreshnik
Published: March 2023

The paper is an attempt to analyse the benefits that remote work could bring in the development of the country. It is organized in three parts. In the first part it engages with the concept of public policy, how it is shaped and should be done to make visible problems that need to be addressed. The second part analysis the benefits of teleworking and potential models for city organization and population distribution to support country development. The last part analyses the case of Albania to discover that remote work, demography, and country development are concepts not yet analysed in connection for exploring the benefits they could bring. The paper concludes that government should invest in developing human resources in the field of digitalisation, so that the number of employees who could telework and companies that could use that expertise is increased. In this way, companies and staff do not necessarily need to locate in the capital or big cities but could locate in medium size cities and periphery. This would contribute to the development of currently neglected areas and decrease living expenses in big cities, making thus more affordable the life for the low-income workers. In doing so, not only the living conditions will improve but the gap between centre and periphery will narrow down and lead to a better distribution of economic benefits across country.
Structural changes of the agriculture in Korça region, aiming the sustainable development
Authors: MAHO Adrian , MAHO Ferdinant
Published: March 2023

Korça region is characterized by advantageous essential factors such as large areas of the fertile soil, a fresh clime, high possibilities for watering, excellent tradition of the distinguished farmers, intellectual resources etc. Agriculture – The economic sector that contributes over 24% of the GDP; • 50% of the employees work in this sector; • 52% of the population lives in rural areas. The aim of this paper is to analyze the current situation of the agriculture sector in Korça region. What are some of the structural changes of the agriculture after the privatization and the transformations of the social system. The structural changes for the agriculture in Korça region have occurred based on the analysis of the economic indicators. The farmers, in fact, are the protagonist of a transition, i.e the transformation from a conventional agriculture and productive to a sustainable and eco-compatible agriculture. The necessary elements for the development of a sustainable agriculture are not only biological or technical, but also social, economic and political and they explain the adequate needs for establishing a sustainable society.
Jerónimo Román de la Higuera. Un mentiroso en tiempos de falsarios
Authors: Betti Miguel
Published: March 2023

El presente trabajo presenta algunas de las controversias ligadas a uno de los principales falsarios de la historia de España, el jesuita Jerónimo Román de la Higuera (c. 1537-1611). El objetivo es demostrar que Higuera no era un caso aislado y que no trabajaba en soledad, sino que tenía contacto con otros falsificadores y que llevó a cabo sus supercherías en un contexto histórico en el que proliferaban las producciones apócrifas.
El cuento del «muchacho de la cola del lobo» en Matías de los Reyes
Authors: Coppola Leonardo
Published: March 2023

El trabajo estudiará el cuento folklórico del «muchacho de la cola del lobo», contenido en El Menandro de Matías de los Reyes. El episodio se halla tanto en la cuentística tradicional italiana de las Trecentonovelle de Sacchetti como en la tradición francesa del suceso inverosímil del Miracles du loup, contenido en Les aventures du baron de Faeneste de Agrippa d’Aubigné. El análisis comparativo intentará demostrar cómo Reyes pudo beber tanto de la componente anecdótica y novellistica de Sacchetti, como del relato autobiográfico y mentiroso de Agrippa d’Aubigné. A la par, el cuento, entendido como desvelador de la naturaleza del personaje que lo pronuncia, muestra en su forma más narrativa la catadura mentirosa de Casandra.
Donde menos se piensa salta la liebre. Los últimos pasos del circuito animal en la carrera caballeresca de don Quijote
Authors: D’Onofrio Julia
Published: March 2023

En el Quijote de 1615, asistimos a un peculiar entramado de representaciones animalísticas, al comprobar que los animales alcanzan mayor relevancia que en la primera parte de 1605. También descubrimos que sus funciones narrativas son muy diversas y dignas de ser estudiadas en detalle. El presente trabajo analiza los últimos encuentros animales que jalonan la aventura vital de don Quijote en su tercera salida. A través de los sentidos simbólicos atribuidos a tales animales en la tradición cultural del Siglo de Oro, sugerimos que el hidalgo llega a leerlos como señales de su propio destino caballeresco.
Citar en variantes: algunas notas sobre la reutilización de romances
Authors: Molinaro Antonietta
Published: March 2023

El trabajo centra la atención en una composición anónima en quintillas, No quiero más amor vano, atestiguada por tres cancioneros áureos de poesías varias. A través de la identificación de tres romances-fuente nunca señalados hasta ahora, se completa la referencia de sus múltiples citas romanceriles, para luego acompañar los viejos y nuevos datos con unas breves consideraciones sobre los efectos de la variabilidad textual propia del romancero en ese ámbito concreto de su reutilización áurea que son los poemas con citas.
La introducción de niponismos en el español del Siglo de Oro
Authors: Rojo-Mejuto Natalia
Published: March 2023

Los niponismos empleados en lengua española son, todavía en investigaciones actuales, clasificados como neologismos, aunque su introducción se produce durante los siglos XVI y XVII. En este trabajo se analiza el léxico japonés en el español áureo, en particular, las voces que han llegado desde esa época hasta hoy. Términos de la alimentación (kaki), las armas (katana), la decoración (biombo, maque), la indumentaria (kimono), la política (shōgun), la religión (bonzo, shintō) y la sociedad (samurai) se emplean en relaciones de sucesos, documentos históricos, diccionarios y obras literarias. Escritores como Francisco de Quevedo o Lope de Vega incluyen algunas de estas voces niponas en sus obras, lo que, unido a los testimonios de religiosos, diplomáticos y mercaderes, demuestra su adopción temprana en el mundo hispánico.
Rehabilitation of Surgically Reconstructed Partially Edentulous Mandible with Iliac Crest Graft After Ameloblastoma Resection with an Implant-Supported “Toronto Prosthesis”
Authors: KAYNAK ÖZTÜRK Esra , KAHRAMAN Şule , DELİLBAŞI Ertan , BARIŞ Emre , BANKOĞLU GÜNGÖR Merve
Published: March 2023

Ameloblastomas are locally invasive and benign odontogenic tumors with a high long-term recurrence rate. These lesions can cause serious anomalies in the facial area and alveolar bones, leading deformity and deterioration of functions. Wide local excision and reconstruction are required for the surgical treatment of these tumors. Aggressive resection effectively eliminates tumors; however, this approach may cause various problems that need reconstruction to restore the oral functions. In the present case report, the rehabilitation of surgically reconstructed partially edentulous mandible with iliac crest graft after ameloblastoma resection with an implant-supported “Toronto Prosthesis” is presented. In the surgical procedure, mandible was partially resected and simultaneous iliac bone graft was applied. Then, four dental implants were inserted into the reconstructed bone and implant-supported Toronto prosthesis was fabricated. The patient was satisfied with the final result of the treatment and recurrence was not observed during the 2-year clinical follow-up.
Mechanosensitive pore opening of a prokaryotic voltage-gated sodium channel
Authors: Strege Peter R , Cowan Luke M , Alcaino Constanza , Mazzone Amelia , Ahern Christopher A , Milescu Lorin S , Farrugia Gianrico , Beyder Arthur
Published: March 2023

Voltage-gated ion channels (VGICs) orchestrate electrical activities that drive mechanical functions in contractile tissues such as the heart and gut. In turn, contractions change membrane tension and impact ion channels. VGICs are mechanosensitive, but the mechanisms of mechanosensitivity remain poorly understood. Here, we leverage the relative simplicity of NaChBac, a prokaryotic voltage-gated sodium channel from Bacillus halodurans, to investigate mechanosensitivity. In whole-cell experiments on heterologously transfected HEK293 cells, shear stress reversibly altered the kinetic properties of NaChBac and increased its maximum current, comparably to the mechanosensitive eukaryotic sodium channel NaV1.5. In single-channel experiments, patch suction reversibly increased the open probability of a NaChBac mutant with inactivation removed. A simple kinetic mechanism featuring a mechanosensitive pore opening transition explained the overall response to force, whereas an alternative model with mechanosensitive voltage sensor activation diverged from the data. Structural analysis of NaChBac identified a large displacement of the hinged intracellular gate, and mutagenesis near the hinge diminished NaChBac mechanosensitivity, further supporting the proposed mechanism. Our results suggest that NaChBac is overall mechanosensitive due to the mechanosensitivity of a voltage-insensitive gating step associated with the pore opening. This mechanism may apply to eukaryotic VGICs, including NaV1.5.
Cell circuits between leukemic cells and mesenchymal stem cells block lymphopoiesis by activating lymphotoxin beta receptor signaling
Authors: Feng Xing , Sun Ruifeng , Lee Moonyoung , Chen Xinyue , Guo Shangqin , Geng Huimin , Müschen Marcus , Choi Jungmin , Pereira Joao Pedro
Published: March 2023

Acute lymphoblastic and myeloblastic leukemias (ALL and AML) have been known to modify the bone marrow microenvironment and disrupt non-malignant hematopoiesis. However, the molecular mechanisms driving these alterations remain poorly defined. Using mouse models of ALL and AML, here we show that leukemic cells turn off lymphopoiesis and erythropoiesis shortly after colonizing the bone marrow. ALL and AML cells express lymphotoxin α1β2 and activate lymphotoxin beta receptor (LTβR) signaling in mesenchymal stem cells (MSCs), which turns off IL7 production and prevents non-malignant lymphopoiesis. We show that the DNA damage response pathway and CXCR4 signaling promote lymphotoxin α1β2 expression in leukemic cells. Genetic or pharmacological disruption of LTβR signaling in MSCs restores lymphopoiesis but not erythropoiesis, reduces leukemic cell growth, and significantly extends the survival of transplant recipients. Similarly, CXCR4 blocking also prevents leukemia-induced IL7 downregulation and inhibits leukemia growth. These studies demonstrate that acute leukemias exploit physiological mechanisms governing hematopoietic output as a strategy for gaining competitive advantage.
Methods of performance analysis in women’s Australian football: a scoping review
Authors: van der Vegt Braedan R. , Gepp Adrian , Keogh Justin W.L. , Farley Jessica B.
Published: March 2023

Background

The first women’s Australian football (AF) professional competition was established in 2017, resulting in advancement in performance analysis capabilities within the sport. Given the specific constraints of women’s AF, it is currently unclear what match-play performance analysis methods and techniques are implemented. Therefore, the aim of this scoping review was to describe and critically appraise physical, technical, and tactical performance analysis methods that have been employed in women’s and girls’ AF match-play.

Methodology

A systematic search was conducted on the 27th of June 2022 through five databases. Eligibility criteria were derived from the PCC framework with the population (P) of women and girls AF players, of any level of play; concepts (C) of interest which were measures, data, and methods related to the sport’s physical, technical, and tactical performance; and the context (C) of methods that analysed any match-play performance. A narrative synthesis was conducted using extracted study characteristic data such as sample size, population, time period, collection standards, evaluation metrics for results, and application of thematic categorisations of previous sports performance reviews. Critical appraisal of eligible studies’ methodologies was conducted to investigate research quality and identify methodological issues.

Results

From 183 studies screened, twelve eligible studies were included, which examined match-play through physical (9/12, 75%), technical (4/12, 33%), and tactical analysis (2/12, 17%). Running demands and game actions analysis were the most researched in senior women’s AF. Research into junior girls’ AF match-play performance has not been investigated. No research has been conducted on non-running physical demands, contact demands, acceleration, and tactical aspects of women’s AF. All studies utilised either inferential statistics or basic predictive models. Critical appraisal deemed most studies as low risk of bias (11/12, 92%), with the remaining study having satisfactory risk.

Conclusions

Future research utilising increased longitudinal and greater contextual data is needed to combat the prominent issue of data representativeness to better characterise performance within women’s and girls’ AF. Additionally, research involving junior and sub-elite AF players across the talent pathways is important to conduct, as it provides greater context and insight regarding development to support the evolving elite women’s AF competition. Women’s AF has been constrained by its resource environment. As such, suggestions are provided for better utilisation of existing data, as well as for the creation of new data for appropriate future research. Greater data generation enables the use of detailed machine learning predictions, neural networks, and network analysis to better represent the intertwined nature of match-play performance from technical, physical, and tactical data.
Sodicity stress differently influences physiological traits and anti-oxidant enzymes in pear and peach cultivars
Authors: Singh Anshuman , Kumar Ashwani , Sharma Parbodh Chander , Kumar Raj , Yadav Rajender Kumar
Published: March 2023

Background

The growth and physiological responses to sodicity stress of pear and peach are poorly understood. Insights into how sodicity stress alters tree physiology remain vital to developing salt tolerant scion and rootstock cultivars.

Methods

The effects of sodicity stress (soil pHs ~8.8) on tree growth and physiological traits of field grown trees of pear cultivars Punjab Beauty and Patharnakh, and peach cultivars Partap and Shan-e-Punjab were recorded using standard procedures. Sodicity-induced changes in oxidative stressors, proline, anti-oxidant enzymes and leaf ions were measured to draw inferences.

Results

Sodicity-induced reductions in vegetative growth were particularly marked in Patharnakh pear and Partap peach compared with other cultivars. Although sodicity stress triggered a significant increase in leaf malondialdehyde (MDA) and hydrogen peroxide (H2O2), their levels relative to controls were much higher in peach than in pear; reflecting that peach suffered from greater oxidative stress. Interestingly, MDA and H2O2 levels did not seem to be deleterious enough to trigger proline-induced osmotic adjustment in pears. The activities of anti-oxidant enzymes strongly varied with the cultivar; specifically, the sodicity-induced increases in CAT and SOD activities were much higher in Punjab Beauty pear and Shan-e-Punjab peach. Principal Component Analysis revealed an explicit convergence between CAT and SOD activities in Punjab Beauty and Shan-e-Punjab cultivars in response to sodicity-induced oxidative stress. Correlation analysis revealed that leaf Na+ strongly inhibited tree growth in peach than in pear. Leaf K+ and proline were found to be the major osmolytes in sodicity-stressed pear and peach cultivars, respectively.

Conclusions

We have for the first time studied the effects of sodicity stress on important tree growth and physiological traits of commercially important pear and peach cultivars. Our findings revealed a marked suppressive effect of sodicity stress on tree growth in peach than in pear. The sodicity-induced upticks in leaf malondialdehyde, hydrogen peroxide and Na+ seemed to induce proline-mediated osmotic adjustment in peach but not in pear. The overall better sodicity tolerance in pear compared to peach was ascribed to increased activities of anti-oxidant enzymes catalase and superoxide dismutase enzymes together with restricted Na+ uptake and better leaf K+ levels. Further investigations are needed to elucidate the effects of sodicity stress on genetic and transcriptional changes, and on fruit yield and quality.
Dihydrotanshinone I inhibits hepatocellular carcinoma cells proliferation through DNA damage and EGFR pathway
Authors: Wang Linjun , Xu Xiangwei , Chen Dexing , Li Chenghang
Published: March 2023

Background

The incidence and mortality of hepatocellular carcinoma (HCC) are globally on the rise. Dihydrotanshinone I, a natural product isolated from Salvia miltiorrhiza Bunge, has attracted extensive attention in recent years for its anti-tumour proliferation efficiency.

Methods

Cell proliferations in hepatoma cells (Huh-7 and HepG2) were evaluated by MTT and colony formation assays. Immunofluorescence (IF) of 53BP1 and flow cytometry analysis were performed to detect DNA damage and cell apoptosis. Furthermore, network pharmacological analysis was applied to explore the potential therapeutic targets and pathway of dihydrotanshinone I.

Results

The results showed that dihydrotanshinone I effectively inhibited the proliferation of Huh-7 and HepG2 cells. Moreover, dihydrotanshinone I dose-dependently induced DNA-damage and apoptosis in vitro. Network pharmacological analysis and molecular simulation results indicated that EGFR might be a potential therapeutic target of dihydrotanshinone I in HCC. Collectively, our findings suggested that dihydrotanshinone I is a novel candidate therapeutic agent for HCC treatment.
Ativismo e modernidade negra
Authors: Figueiredo Angela
Published: March 2023

Resenha de;
GUIMARÃES, Antonio Sérgio Alfredo. Modernidades negras: a formação racial brasileira (1930-1970). São Paulo: Editora 34, 2021. 295 p.
O Afropessimismo e a antinegritude do mundo
Authors: Natali Marcos
Published: March 2023

Resenha de:
WILDERSON III, Frank B. Afropessimismo. São Paulo: Todavia, 2021. 400 p.
Association Between Medicaid Waivers and Medicaid Disenrollment Among Autistic Adolescents During the Transition to Adulthood
Authors: Carey Meghan E. , Tao Sha , Koffer Miller Kaitlin H. , Marcus Steven C. , Mandell David S. , Epstein Andrew J. , Shea Lindsay L.
Published: March 2023

This cohort study examines whether Medicaid waivers were associated with a reduced risk of Medicaid disenrollment among autistic adolescents who are transitioning to adulthood.
Incidence of SARS-CoV-2 Infection Among People Experiencing Homelessness in Toronto, Canada
Authors: Richard Lucie , Nisenbaum Rosane , Brown Michael , Liu Michael , Pedersen Cheryl , Jenkinson Jesse I. R. , Mishra Sharmistha , Baral Stefan , Colwill Karen , Gingras Anne-Claude , McGeer Allison , Hwang Stephen W.
Published: March 2023

Importance

People experiencing homelessness are at high risk of SARS-CoV-2 infection. Incident infection rates have yet to be established in these communities and are needed to inform infection prevention guidance and related interventions.

Objective

To quantify the SARS-CoV-2 incident infection rate among people experiencing homelessness in Toronto, Canada, in 2021 and 2022 and to assess factors associated with incident infection.

Design, Setting, and Participants

This prospective cohort study was conducted among individuals aged 16 years and older who were randomly selected between June and September 2021 from 61 homeless shelters, temporary distancing hotels, and encampments in Toronto, Canada.

Exposures

Self-reported housing characteristics, such as number sharing living space.

Main Outcomes and Measures

Prevalence of prior SARS-CoV-2 infection in summer 2021, defined as self-reported or polymerase chain reaction (PCR)– or serology-confirmed evidence of infection at or before the baseline interview, and SARS-CoV-2 incident infection, defined as self-reported or PCR- or serology-confirmed infection among participants without history of infection at baseline. Factors associated with infection were assessed using modified Poisson regression with generalized estimating equations.

Results

The 736 participants (415 of whom did not have SARS-CoV-2 infection at baseline and were included in the primary analysis) had a mean (SD) age of 46.1 (14.6) years; 486 (66.0%) self-identified as male. Of these, 224 (30.4% [95% CI, 27.4%-34.0%]) had a history of SARS-CoV-2 infection by summer 2021. Of the remaining 415 participants with follow-up, 124 experienced infection within 6 months, representing an incident infection rate of 29.9% (95% CI, 25.7%-34.4%), or 5.8% (95% CI, 4.8%-6.8%) per person-month. Report after onset of the SARS-CoV-2 Omicron variant was associated with incident infection, with an adjusted rate ratio (aRR) of 6.28 (95% CI, 3.94-9.99). Other factors associated with incident infection included recent immigration to Canada (aRR, 2.74 [95% CI, 1.64-4.58]) and alcohol consumption over the past interval (aRR, 1.67 [95% CI, 1.12-2.48]). Self-reported housing characteristics were not significantly associated with incident infection.

Conclusions and Relevance

In this longitudinal study of people experiencing homelessness in Toronto, SARS-CoV-2 incident infection rates were high in 2021 and 2022, particularly once the Omicron variant became dominant in the region. Increased focus on homelessness prevention is needed to more effectively and equitably protect these communities.
Maternal Emergency Department Use Before Pregnancy and Infant Emergency Department Use After Birth
Authors: Varner Catherine E. , Park Alison L. , Ray Joel G.
Published: March 2023

Importance

Maternal emergency department (ED) use before or during pregnancy is associated with worse obstetrical outcomes, for reasons including preexisting medical conditions and challenges in accessing health care. It is not known whether maternal prepregnancy ED use is associated with higher use of the ED by their infant.

Objective

To study the association between maternal prepregnancy ED use and risk of infant ED use in the first year of life.

Design, Setting, and Participants

This population-based cohort study included all singleton livebirths in all of Ontario, Canada, from June 2003 to January 2020.

Exposures

Any maternal ED encounter within 90 days preceding the start of the index pregnancy.

Main Outcomes and Measures

Any infant ED visit up to 365 days after the index birth hospitalization discharge date. Relative risks (RR) and absolute risk differences (ARD) were adjusted for maternal age, income, rural residence, immigrant status, parity, having a primary care clinician, and number of prepregnancy comorbidities.

Results

There were 2 088 111 singleton livebirths; the mean (SD) maternal age was 29.5 (5.4) years, 208 356 (10.0%) were rural dwelling, and 487 773 (23.4%) had 3 or more comorbidities. Among singleton livebirths, 206 539 mothers (9.9%) had an ED visit within 90 days before the index pregnancy. ED use in the first year of life was higher among infants whose mother had visited the ED before pregnancy (570 per 1000) vs those whose mother had not (388 per 1000) (RR, 1.19 [95% CI, 1.18-1.20]; ARD, 91.1 per 1000 [95% CI, 88.6-93.6 per 1000]). Compared with mothers without a prepregnancy ED visit, the RR of infant ED use in the first year was 1.19 (95% CI, 1.18-1.20) if its mother had 1 prepregnancy ED visit, 1.18 (95% CI, 1.17-1.20) following 2 visits, and 1.22 (95% CI, 1.20-1.23) after at least 3 maternal visits. A low-acuity maternal prepregnancy ED visit was associated with an adjusted odds ratio (aOR) of 5.52 (95% CI, 5.16-5.90) for a low-acuity infant ED visit, which was numerically higher than the pairing of a high-acuity ED use between mother and infant (aOR, 1.43, 95% CI, 1.38-1.49).

Conclusions and Relevance

In this cohort study of singleton livebirths, prepregnancy maternal ED use was associated with a higher rate of ED use by the infant in the first year of life, especially for low-acuity ED use. This study’s results may suggest a useful trigger for health system interventions aimed at reducing some ED use in infancy.
Diagnostic Accuracy of Portable, Handheld Point-of-Care Tests vs Laboratory-Based Bilirubin Quantification in Neonates
Authors: Westenberg Lauren E. H. , Been Jasper V. , Willemsen Sten P. , Vis Jolande Y. , Tintu Andrei N. , Bramer Wichor M. , Dijk Peter H. , Steegers Eric A. P. , Reiss Irwin K. M. , Hulzebos Christian V.
Published: March 2023

Importance

Quantification of bilirubin in blood is essential for early diagnosis and timely treatment of neonatal hyperbilirubinemia. Handheld point-of-care (POC) devices may overcome the current issues with conventional laboratory-based bilirubin (LBB) quantification.

Objective

To systematically evaluate the reported diagnostic accuracy of POC devices compared with LBB quantification.

Data Sources

A systematic literature search was conducted in 6 electronic databases (Ovid MEDLINE, Embase, Web of Science Core Collection, Cochrane Central Register of Controlled Trials, CINAHL, and Google Scholar) up to December 5, 2022.

Study Selection

Studies were included in this systematic review and meta-analysis if they had a prospective cohort, retrospective cohort, or cross-sectional design and reported on the comparison between POC device(s) and LBB quantification in neonates aged 0 to 28 days. Point-of-care devices needed the following characteristics: portable, handheld, and able to provide a result within 30 minutes. This study was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-analyses reporting guideline.

Data Extraction and Synthesis

Data extraction was performed by 2 independent reviewers into a prespecified, customized form. Risk of bias was assessed using the Quality Assessment of Diagnostic Accuracy Studies 2 tool. Meta-analysis was performed of multiple Bland-Altman studies using the Tipton and Shuster method for the main outcome.

Main Outcomes and Measures

The main outcome was mean difference and limits of agreement in bilirubin levels between POC device and LBB quantification. Secondary outcomes were (1) turnaround time (TAT), (2) blood volumes, and (3) percentage of failed quantifications.

Results

Ten studies met the inclusion criteria (9 cross-sectional studies and 1 prospective cohort study), representing 3122 neonates. Three studies were considered to have a high risk of bias. The Bilistick was evaluated as the index test in 8 studies and the BiliSpec in 2. A total of 3122 paired measurements showed a pooled mean difference in total bilirubin levels of −14 μmol/L, with pooled 95% CBs of −106 to 78 μmol/L. For the Bilistick, the pooled mean difference was −17 μmol/L (95% CBs, −114 to 80 μmol/L). Point-of-care devices were faster in returning results compared with LBB quantification, whereas blood volume needed was less. The Bilistick was more likely to have a failed quantification compared with LBB.

Conclusions and Relevance

Despite the advantages that handheld POC devices offer, these findings suggest that the imprecision for measurement of neonatal bilirubin needs improvement to tailor neonatal jaundice management.