bluuebunny/crossref_metadata_2025 huggingface dataset:
Changes in reasons for visits to primary care after the start of the COVID-19 pandemic: An international comparative study by the International Consortium of Primary Care Big Data Researchers (INTRePID)
Authors: Tu Karen , Lapadula María C. , Apajee Jemisha , Bonilla Angela Ortigoza , Baste Valborg , Cuba-Fuentes María S. , de Lusignan Simon , Flottorp Signe , Gaona Gabriela , Goh Lay Hoon , Hallinan Christine M. , Kristiansson Robert S. , Laughlin Adrian , Li Zhuo , Ling Zheng J. , Manski-Nankervis Jo-Anne , Ng Amy P. P. , Scattini Luciano F. , Silva-Valencia Javier , Pace Wilson D. , Wensaas Knut-Arne , Wong William C. W. , Zingoni Paula L. , Westfall John M. ,   on behalf of INTRePID
Published: August 2024

Background

The COVID-19 pandemic has reshaped healthcare delivery worldwide.

Objective

To explore potential changes in the reasons for visits and modality of care in primary care settings through the International Consortium of Primary Care Big Data Researchers (INTRePID).

Methods

We conducted a cross-sectional, retrospective study from 2018–2021. We examined visit volume, modality, and reasons for visits to primary care in Argentina, Australia, Canada, China, Peru, Norway, Singapore, Sweden, and the USA. The analysis involved a comparison between the pre-pandemic and pandemic periods.

Results

There were more than 215 million visits from over 38 million patients during the study period in INTRePID primary care settings. Most INTRePID countries experienced a decline in monthly visit rates during the first year of the pandemic, with rate ratios (RR) and 95% confidence intervals (CI) ranging from RR:0.57 (95%CI:0.49–0.66) to RR:0.90 (95%CI:0.83–0.98), except for in Canada (RR:0.99, 95%CI:0.94–1.05) and Norway (RR:1.00, 95%CI:0.92–1.10), where rates remained stable and in Australia where rates increased (RR:1.19, 95%CI:1.11–1.28). Argentina, China, and Singapore had limited or no adoption of virtual care, whereas the remaining INTRePID countries varied in the extent of virtual care utilization. In Peru, virtual visits accounted for 7.34% (95%CI:7.33%-7.35%) of all interactions in the initial year of the pandemic, dipping to 5.22% (95%CI:5.21%-5.23%) in the subsequent year. However, in Canada 75.30% (95%CI:75.20%-75.40%) of the visits in the first year were virtual, decreasing to 62.77% (95%CI:62.66%-62.88%) in the second year. Diabetes, hypertension and/or hyperlipidemia and general health exams were in the top 10 reasons for visits in 2019 for all countries. Anxiety, depression and/or other mental health related reasons were among the top 10 reasons for virtual visits in all countries that had virtual care.

Conclusions

The pandemic resulted in changes in reasons for visits to primary care, with virtual care mitigating visit volume disruptions in many countries.
Patients report high information coordination between rostered primary care physicians and specialists: A cross-sectional study
Authors: Rahman Bahram , Babe Glenda , Griffith Lauren E. , Price David , Lapointe-Shaw Lauren , Costa Andrew P.
Published: August 2024

Our study aimed to describe patient experience of information coordination between their primary care physician and specialists and to examine the associations between their experience and their personal and primary care characteristics. We conducted a cross-sectional study of Ontario residents rostered to a primary care physician and visited a specialist physician in the previous 12 months by linking population-based health administrative data to the Health Care Experience Survey collected between 2013 and 2020. We described respondents’ sociodemographic and health care utilization characteristics and their experience of information coordination between their primary care physician and specialists. We measured the adjusted association between patient-reported measures of information coordination before and after respondents received care from a specialist physician and their type of primary care model. 1,460 out 20,422 (weighted 7.5%) of the respondents reported that their specialist physician did not have basic medical information about their visit from their primary care physician in the previous 12 months. 2,298 out of 16,442 (weighted 14.9%) of the respondents reported that their primary care physician seemed uninformed about the care they received from the specialist. Females, younger individuals, those with a college or undergraduate level of education, and users of walk-in clinics had a higher likelihood of reporting a lack of information coordination between the primary care and specialist physicians. Only respondents rostered to an enhanced fee-for-service model had a higher odds of reporting that the specialist physician did not have basic medical information about their visit compared to those rostered to a Family Health Team (OR 1.22, 95% Cl 1.12–1.40). We found no significant association between respondent’s type of primary care model and that their primary care physician was uninformed about the care received from the specialist physician. In this population-based health study, respondents reported high information coordination between their primary care physician and specialists. Except for respondents rostered to an enhanced fee-for-service model of care, we did not find any difference in information coordination across other primary care models.
Insilico exploration C. koseri ATP synthase inhibitors by pharmacophore-based virtual screening, molecular docking and MD simulation
Authors: Alanzi Abdullah R. , A. Z. Alanazi , Alhazzani Khalid
Published: August 2024

Citrobacter koseri is a gram-negative rod that causes infections in people who have significant comorbidities and are immunocompromised. Antibiotic-resistant strains are becoming more common, which complicates infection treatment and highlights the need for innovative, effective drugs to fight these resistant strains. The enzyme complex ATP synthase participates in the adenosine triphosphate (ATP) synthesis, the fundamental energy currency of cells. This study used Computer-Aided Drug Design approaches to identify potential inhibitors of C. koseri ATP synthase. SWISS-MODEL was used to predict the 3D structure of C. koseri ATP synthase. A ligand-based pharmacophore model was developed using chemical features of ampicillin. Following ligand-based virtual screening across nine databases, the 2043 screened hits were docked to the ATP synthase active site using the standard precision mode of the glide tool. Based on their binding affinities, the top ten compounds were selected for additional investigation. The binding affinities of the chosen compounds ranged from -10.021 to -8.452 kcal/mol. The top four compounds (PubChem-25230613, PubChem-74936833, CHEMBL263035, PubChem-44208924) with the best ADMET characteristics and binding modes were chosen. Thus, the feasible binding mechanisms of the selected compounds were subjected to stability analysis using the MD Simulation study, which revealed the compounds’ stability as potent inhibitors within the protein binding pocket. This computational approach provides important insights into the rational design of novel therapeutics and emphasizes the importance of targeting essential metabolic pathways when combating antibiotic-resistant pathogens. Future experimental validation and optimization of the identified inhibitors is required to determine their efficacy and safety profiles for clinical use.
Needs and capabilities for improving poultry production and health management in Indonesia
Authors: Chapot Lorraine , Hibbard Rebecca , Ariyanto Kurnia Bagus , Maulana Kusnul Yuli , Yusuf Havan , Febriyani Widya , Cameron Angus , Paul Mathilde , Vergne Timothée , Faverjon Céline
Published: August 2024

In Indonesia, the development of the poultry industry is facing numerous challenges. Major constraints include high disease burdens, large fluctuations in farm input and output prices, and inadequate biosecurity. Timely and reliable information about animal production and health can help stakeholders at all levels of the value chain make appropriate management decisions to optimize their profitability and productivity while reducing risks to public health. This study aimed to describe the challenges in the Indonesian poultry industry, assess stakeholders’ needs and capabilities in terms of generating and using poultry information for making production and health management decisions, and identify levers for improvement. Interviews were conducted with a diversity of key informants and value chain actors in five Indonesian provinces. Thematic analysis was applied with an interpretivist approach to gain an in-depth understanding of the lived experiences of various stakeholders and their opinions as to what might constitute appropriate solutions. Our findings indicate that market and political instability, ineffective management of poultry data, and limited inter-sectoral collaboration are limiting the development of the sector. Increased intersectoral cooperation is needed to implement standards for data collection and sharing across the industry, provide education and practical training on the use of information technologies for farm management, and accelerate research and innovation. Our study can contribute to the development of data-driven tools to support evidence-based decision-making at all levels of the poultry system.
Gender differences in research fields of bioeconomy and rural development-based on sustainable systems in Latin America and Africa regions
Authors: Olivo M. Lourdes Ordoñez , Oluwakemi Rachael Adeleye , Lakner Zoltán , Farkas Tibor
Published: August 2024

Using bibliometric analysis of large-scale publication data is a simple approach to exploring gender-related trends, especially gender equality in academic publishing. The aim of this study is to investigate gender trends in the fields of bio-economy and rural development sciences in two under develop regions as Latin America and Africa. This study examines gender differences in these fields in order to: (1) recognize the contribution of female researchers in bioeconomy and rural development, (2) explore the relational structure of gender aspects in academic publications, (3) identify trends in female authorship in these scientific research fields over time, and finally (4) identify gender potentials for women to become more visible in these fields of study. To achieve these objectives, we used bibliometric tools to analyses 1891 publication records in bioeconomy and rural development. After cleaning the database of full names of authors of academic publications relevant to the field studies, we performed a series of statistical analyses in R and SPSS software, such as Lotkas distribution, network analysis, co-authorship analysis and spatial distribution of authors in the study. The results show that the number of male authors is almost three times higher than the number of female authors, suggesting that women are under-represented in the fields studied. Men occupy the most important position of authorship in scientific articles; publications with corresponding male authors were found in 1389 out of 1891 publications related to the bio-economy and rural development. In terms of geographical regions, publications with female authors were more prevalent in European and North American areas, with a small exception in some developing countries such as Argentina and South Africa. In terms of research networks, from the total number of authors evaluated, only 23% are female authors on the map of research influence. This indicates that there is a significant gap to be filled in the promotion of scholarly impact through the sharing of knowledge and expertise among authors.
Complete mitochondrial genomes of three vulnerable cave bat species and their phylogenetic relationships within the order Chiroptera
Authors: Molina Michele , Oliveira Guilherme , Oliveira Renato R. M. , Nunes Gisele L. , Pires Eder S. , Prous Xavier , Ribeiro Mariane , Vasconcelos Santelmo
Published: August 2024

The IUCN Red List of Threatened Species contains 175 Brazilian bat species that are threatened by extinction in some degree. From this perspective, it is essential to expand the knowledge about the genetic diversity of vulnerable bats. Genomic sequencing can be useful to generate robust and informative genetic references, increasing resolution when analyzing relationships among populations, species, or higher taxonomic levels. In this study, we sequenced and characterized in detail the first complete mitochondrial genomes of Furipterus horrens, Lonchorhina aurita, and Natalus macrourus, and investigated their phylogenetic position based on amino acid sequences of protein-coding genes (PCGs). The mitogenomes of these species are 16,516, 16,697, and 16,668 bp in length, respectively, and each comprises 13 PCGs, 22 tRNA genes, two rRNA genes, and a putative control region (CR). In the three species, genes were arranged similarly to all other previously described bat mitogenomes, and nucleotide composition was also consistent with the reported range. The length and arrangement of rrnS and rrnL were also consistent with those of other bat species, showing a positive AT-skew and a negative GC-skew. Except for trnS1, for which we did not observe the DHU arm, all other tRNAs showed the cloverleaf secondary structure in the three species. In addition, the mitogenomes showed minor differences in start and stop codons, and in all PCGs, codons ending in adenine were more common compared to those ending in guanine. We found that PCGs of the three species use multiple codons to encode each amino acid, following the previously documented pattern. Furthermore, all PCGs are under purifying selection, with atp8 experiencing the most relaxed purifying selection. Considering the phylogenetic reconstruction, F. horrens was recovered as sister to Noctilio leporinus, L. aurita and Tonatia bidens shared a node within Phyllostomidae, and N. macrourus appeared as sister to Molossidae and Vespertilionidae.
Effectiveness of PCSK9 inhibitors: A Target Trial Emulation framework based on Real-World Electronic Health Records
Authors: Barbati Giulia , Gregorio Caterina , Scagnetto Arjuna , Indennidate Carla , Cappelletto Chiara , Di Lenarda Andrea
Published: August 2024

Low-Density Lipoprotein (LDL) cholesterol is one of the main target for cardiovascular (CV) prevention and therapy. In the last years, Proprotein Convertase Subtilisin–Kexin type 9 inhibitors (PCSK9-i) has emerged as a key therapeutic target to lower LDL and were introduced for prevention of CV events. Recently (June 2022) the Italian Medicines Agency (AIFA) modified the eligibility criteria for the use of PCSK9-i. We designed an observational study to estimate the prevalence of eligible subjects and evaluate the effectiveness of PCSK9-i applying a Target Trial Emulation (TTE) approach based on Electronic Health Records (EHR). Subjects meeting the eligibility criteria were identified from July 2017 (when PCSK9-i became available) to December 2020. Outcomes were all-cause death and the first hospitalization. Among eligible subjects, we identified those treated at date of the first prescription. Inverse Probability of Treatment Weights (IPTW) were estimated including demographic and clinical covariates, history of treatment with statins and the month/year eligibility date. Competing risk models on weighted cohorts were used to derive the Average Treatment Effect (ATE) and the Conditional Average Treatment Effect (CATE) in subgroups of interest. Out of 1976 eligible subjects, 161 (8%) received treatment with PCSK9-i. Treated individuals were slightly younger, predominantly male, had more severe CV conditions, and were more often treated with statin compared to the untreated subjects. The latter exhibited a higher prevalence of non-CV comorbidities. A significant absolute and relative risk reduction of death and a lower relative risk for the first hospitalization was observed. The risk reduction for death was confirmed in CATE analysis. PCSk9-i were prescribed to a minority of eligible subjects. Within the TTE framework, the analysis confirmed the association between PCSK9-i and lower risk of events, aligning with findings from randomized clinical trials (RCTs). In our study, PCSK9-i provided protection specifically against all-cause death, expanding upon the evidence from RCTs that had primarily focused on composite CV outcomes.
«Es lo que fue, es lo que es, es lo que será»
Authors: Rubio Echazarra Ane
Published: August 2024

El ritmo de consumo actual está basado en el consumismo desmedido que lejos de ofrecer una vida consciente y un futuro digno, precipita al mundo que conocemos hoy a un colapso relativamente inmediato. Dentro de este contexto tan desolador, este artículo presenta un proyecto artístico que busca una alternativa a procesos que permitan imaginar futuros más positivos basados en un acercamiento y un respeto a la naturaleza y a los recursos que esta misma ofrece. El proyecto «Es lo que fue, es lo que es, es lo que será» se basa en la efimeridad y en la reutilización de los propios materiales utilizados o recuperados, con la intención de comenzar una búsqueda a maneras alternativas de producir artísticamente dentro de este contexto. Al mismo tiempo, tiene como objetivo generar un espacio de duda y cuestionamiento de patrones capitalistas y consumistas de los que no se es consciente, con la intención de encuadrar las categorías de sostenibilidad y práctica ecológica dentro del arte.
texto como practica ecoartivista
Authors: Álvarez-Borrajo Lucía , Arregui-Pradas Rocío
Published: August 2024

En estas páginas se expone un texto que ha sido creado de forma colaborativa. Enmarcada en la encrucijada de la crisis medioambiental, establecemos que la escritura performativa como forma narrativa facilita mecanismos de enunciación que visibiliza estrategias de resistencia en los que se conjugan saberes periféricos y conocimiento crítico. En primer lugar, se realiza una aproximación a la definición de escritura performativa; a continuación, partiendo de la experiencia personal vivida en un contexto rural se abocetan rasgos en común con la teoría ecofeminista. Además, se subraya la autoetnografía como un importante método de investigación cualitativo para realizar un análisis de la experiencia personal conectada con el contexto cultural. A modo de conclusión, se reseña el entrelazamiento de disciplinas y contextos, y la importancia de la participación en redes culturales reales, destacando el ejemplo de mediación llevada a cabo por El Cubo Verde en el proyecto «Culturarios | Humus de iniciativas culturales en el campo».
Musika popularraren ahalmenak trantsizio ekosozialean
Authors: Barcena Hinojal Iñaki , Larrinaga Arza Josu Xabier
Published: August 2024

Artikulu honetan, gizarte- eta ingurumen-problematikaren eta kultura-aldaketaren arteko interes-korapiloen bilaketa egin nahi dugu, eta zehazki, musikak kapitalismo industrialaren iruditegi hegemonikoen sorkuntzan eta erreprodukzioan edo, aitzitik, eredu suntsitzaile kapitalistaren kritikan izan duen zeregina. Esate baterako, musika batzuk imajinario anti-ekologikoen ibilgailu gisa erabili dira, kultura kontsumista sortzeko duen zereginean sakontzen, eta beste kasu batzuetan, gaur egun gutxiengoa direla eta, gure harreman sozio-ekologikoetan norabide aldaketa aldarrikatzen duten musikak topatzen ditugu, hau da, ekosistemekiko eta gure arteko harremanak gizaki gisa eraldatu nahi dutenak.
A Brief Model Evaluated Outcomes After Liver Transplantation Based on the Matching of Donor Graft and Recipient
Authors: Li Yuancheng , Liu Xingchao , Zhang Chengcheng , Tao Ran , Pan Bi , Liu Wei , Jiang Di , Hu Feng , Xu Zeliang , Tan Dehong , Ou Yanjiao , Li Xun , You Yuemei , Zhang Leida
Published: August 2024

INTRODUCTION:

A precise model for predicting outcomes is needed to guide perioperative management. With the development of the liver transplantation (LT) discipline, previous models may become inappropriate or noncomprehensive. Thus, we aimed to develop a novel model integrating variables from donors and recipients for quick assessment of transplant outcomes.

METHODS:

The risk model was based on Cox regression in a randomly selected derivation cohort and verified in a validation cohort. Perioperative data and overall survival were compared between stratifications grouped by X-tile. Receiver-operating characteristic curve and decision curve analysis were used to compare the models. Violin and raincloud plots were generated to present post-LT complications distributed in different stratifications.

RESULTS:

Overall, 528 patients receiving LT from 2 centers were included with 2/3 in the derivation cohort and 1/3 in the validation cohort. Cox regression analysis showed that cold ischemia time (CIT) (P = 0.012) and Model for End-Stage Liver Disease (MELD) (P = 0.007) score were predictors of survival. After comparison with the logarithmic models, the primitive algorithms of CIT and MELD were defined as the CIT-MELD Index (CMI). CMI was stratified by X-tile (grade 1 ≤1.06, 1.06 < grade 2 ≤ 1.87, grade 3 >1.87). In both cohorts, CMI performed better in calculating transplant outcomes than the balance of risk score, including perioperative incidents and prevalence of complications.

DISCUSSION:

The model integrating variables from graft donors and recipients made the prediction more accurate and available. CMI provided new insight into outcome evaluation and risk factor management of LT.
Baricitinib: key results of long-term use in rheumatoid arthritis
Authors: Chichasova N. V. , Lila A. M.
Published: August 2024

This review presents the latest data on the long-term use of the selective Janus kinase inhibitor (JAKi) baricitinib (BARI) in patients with rheumatoid arthritis (RA) in real-world clinical practice. The results of long-term use (up to 9.5 years) of BARI in RA suggest that its efficacy is comparable or even superior to that of biologic disease-modifying antirheumatic drugs (bDMARDs) and tofacitinib, while the drug is more effective in patients who have not previously received bDMARDs or JAKi. It has been shown that the BARI dose can be reduced to 2 mg/day once the treatment goal has been reached in most patients without a decrease in efficacy, and that exacerbations that have occurred after reduction of the dosage (or treatment interruption) are relieved when returning to the full dose of the drug. According to data from registries from many countries and open observational studies, BARI is well tolerated during long-term use, even in elderly patients with ≥1 risk factor for cardiovascular disease. A high survival rate with BARI therapy has also been observed, which according to some registries exceeds that of tumor necrosis factor α inhibitors. Against the background of BARI therapy, a rapid (within 1 to 3 months) statistically significant reduction in pain has been demonstrated, regardless of the degree of suppression of disease activity, which correlates with an improvement in the functional status and general condition of patients. The possibility of suppressing the progression of structural damage in patients with RA was also demonstrated, allowing the choice of individualized tactics for the management of such patients.
Characteristics of clinical manifestations and pharmacotherapy in patients with rheumatoid arthritis requiring switching between biologic disease-modifying antirheumatic drugs and Janus kinase inhibitors
Authors: Bobkova A. O. , Lila A. M. , Karateev A. E.
Published: August 2024

Biologic disease-modifying antirheumatic drugs (bDMARDs) and Janus kinase inhibitors (JAKis) do not always allow to achieve remission and low inflammatory activity in rheumatoid arthritis (RA), necessitating switching of therapy. Objective: to evaluate the clinical characteristics and features of pharmacotherapy in patients with RA requiring a switch from bDMARD/JAKi. Material and methods. The study group consisted of 103 patients with RA (85.4% women, mean age 46.9±13.7 years) who had persistent disease activity (DAS28-CRP – 5.42±0.9) despite treatment with bDMARD/JAKi or who experienced adverse events requiring therapy switching. Patients were divided into three groups: Group 1 – patients who underwent one switch (n=50), Group 2 – 2 switches (n=39), Group 3 – ≥3 switches (n=14) of bDMARD/JAKi therapy. Clinical manifestations, disease activity and pharmacotherapy were assessed. Results and discussion. The main reason for switching therapy was ineffectiveness of bDMARD/JAKi (in 81.6% of patients). There was a tendency towards higher DAS28-ESR (p=0.052) and DAS28-CRP values (p=0.057) in groups 2 and 3 compared to group 1, as well as significant differences in CDAI (p1–2=0.015 and p1–3=0.011) and SDAI (p1–2=0.013 and p1–3=0.01). In group 3, there was a tendency towards higher DAS28-CRP, CDAI and SDAI values compared to group 2: 5.82±0.92 and 5.53±0.89; 40.5 [33.0; 45.0] and 35.2 [30.3; 43.9]; 36 [32; 42] and 32.0 [28.5; 38.5], respectively. However, these differences were statistically insignificant. Patients in groups 2 and 3 had a significantly higher number of painful joints compared to patients in group 1 (p1–2=0.048 and p1–3=0.036) and a significantly higher patient global assessment of disease activity (p1–2=0.004 and p1–3=0.013). Patients in group 3 took glucocorticoids significantly longer and at higher doses than patients in group 1. Tumour necrosis factor-α inhibitors were used more frequently in groups 1 and 2 (50.0 and 41.0%, respectively), and interleukin-6 inhibitors in group 3 (50.0%). Conclusion. Patients with RA who required ≥2 switches of bDMARD/JAKi had higher disease activity compared to patients who required only one switch of therapy.
Cutaneous necrotizing vasculitis in a patient with rheumatoid arthritis that developed after COVID-19: description of a clinical case
Authors: Balabanova R. M. , Denisov L. N.
Published: August 2024

The article discusses the pathogenesis and clinical manifestations of cutaneous vasculitis in rheumatoid arthritis (RA) and the role of autoimmune disturbances in the development of micro- and macrovascular thrombosis of the venous and arterial vessels caused by SARS-CoV-2 virus infection. A clinical case is described in which skin necrosis in the elbow joint area developed in a patient with a long-term course of RA after COVID-19. The process subsided against the background of treatment with an interleukin-6 inhibitor.
Impact of Vaginal Microbiota on Cervical Intraepithelial Neoplasia, Human Papillomavirus Infection, and Cervical Cancer Prevention
Authors: Ahmad S. Rehan , Ghosh Pritha
Published: August 2024

Cervical cancer ranks as the fourth most prevalent cancer among women globally, with human papilloma virus (HPV) infection and other vaginal infections playing crucial roles in cervical lesion progression. While the body’s immune system can often combat HPV infections, conventional cervical cancer treatments may have cytotoxic effects. Therefore, prioritizing strategies to either decrease HPV infection rates or mitigate existing cervical cancer severity is vital. Certain Lactobacillus strains, prominent in the vaginal microbial community, contribute to vaginal epithelium protection by inhibiting pathogen colonization and producing antibacterial substances like bacteriocins. This review explores how cervicovaginal microbiota, particularly dominated by Lactobacillus species, can lower HPV infection risk, and impede cervical cancer progression. Emphasizing the probiotic impact, the article delves into the potential of vaginal lactobacilli and bacteriocin-producing strains against cervical intraepithelial neoplasia (CIN) and cervical cancer, highlighting underlying mechanisms. A healthy vaginal microbiota emerges as pivotal in averting diverse genital tract infections, preventing cervical lesions, and ultimately reducing the risk of cervical cancer.
Environmental Damage: Community Lawsuit Against The Government Over Industrial Business Licenses
Authors: Amiq Bachrul , Borman M. Syahrul , Taufik Moh , Aranggraeni Renda , Astuti Pudji , Aimim-Tham Sukanya , Aminah Aminah
Published: August 2024

Legal policies causing environmental damage raise questions about legal standing to file lawsuits with the State Administrative Court and its authority over business license disputes. This study examines the challenges and opportunities in implementing the authority of the state administrative court as a form of law enforcement on business licenses that impact environmental damage. This study uses the qualitative method NVivo12 Plus 12 by analyzing legal rules, journals, and online print media such as detik.com and kompas.com. The research focuses on the approach of laws and regulations related to the environment and case studies based on Supreme Court decisions. The Administrative Court plays a role in receiving claims against government actions that harm citizens. One of them is the authority to adjudicate disputes over government actions related to environmental disputes. Community participation is essential to create a healthy environment and is used not only as a means to an end but also as an end. The right to a healthy climate encompasses the right to receive environmental information, participate in decision-making, and review challenging public decisions within the scope of access to justice.
Use of Marsupialization as a Definitive Treatment for Large-sized Dentigerous Cysts in a Patient with Mucopolysaccharidosis Type I
Authors: de Menezes Pedro Henrique Moraes , Teixeira Maria Clara Corrêa de Almeida , Fernandes Cleone de Fátima Oliveira Neder , Bastos Marden Oliveira , Oliveira Marina Reis , Mariano Ronaldo Celio
Published: August 2024

The correct diagnosis is fundamental for the appropriate treatment to be employed in a particular pathology. The best treatment is not the one that solves only local problems, fragmenting the patient, and therefore, it is necessary to integrate the entire systemic condition of the individual before initiating any local treatment. This context inevitably requires dentistry to participate in a multidisciplinary approach, where the role of the dentist is expanded in concepts that encompass ethics, human dignity, and professional valorization. This article describes a clinical case of a patient with mucopolysaccharidosis type I, whose treatment of cystic lesions present in the mandible was exclusively performed through marsupialisation. The objective of this study is to demonstrate, within the complexity of this rare syndrome, the difficulties of diagnosis and the need for evaluation of the patient beyond the limits of the oral cavity, as well as to report two cases of large dentigerous cysts, surgically treated conservatively through marsupialisation, without the need for re-approach for enucleation and without recurrences over a 20-year period.
Ruptured Liver Abscess Post Severe COVID-19 Infection: A Case Report
Authors: Isa Mohd Firdaus Mohd , Ghazi Faiz Najmuddin , Merican Siti Rahmah Hashim Isa , Zulkifli Ahmad Zuraimi , Singh Premjeet
Published: August 2024

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2) caused imminent acute infection of respiratory tract known as Coronavirus disease 2019 (COVID-19). Complications of hepatobiliary system especially liver often found in post-acute COVID-19 patients. However, there are only few studies specifically discussing about liver abscess in patients who had history of contracted COVID-19. We present a case of a 54-years-old gentleman with no previous medical illness and no history of vaccination, who was presented with ruptured liver abscess post COVID-19 infection Category 4 (symptomatic with lung infection and the need of oxygen supplementation). Percutaneous drainage was performed to drain the abscess and collections.
Resources of Inula grandis Schrenk ex Fisch. & C.A. Mey. in South Uzbekistan
Authors: Mahmudov Azizbek , Abduraimov Ozodbek , Allamurotov Akmal , Maxmudov V  , Mavlanov Bekzod , Mamatkasimov Odilbek
Published: August 2024

The article describes the resources of underground phytomass Inula grandis in the southern part of Uzbekistan. The soil type of the studied areas refers to mountain-crushed (Lithosols) soils. The optimum location for soil types and altitude above sea level is mountainous-crushed soils at altitudes of 1300-1500 m altitudes above sea level. The phytocoenotic optimum is distributed among the herb-shrub-juniper community. The yield of underground phytomass in the Kashkadarya region averages 261.2 kg/ha and in the Surkhandarya region, 236.3 kg/ha. The volume of possible annual harvesting in the Kashkadarya region is 1.24 tons from 7.0 ha of resource areas. These indicators were recorded in the Surkhandarya region: 3.92 tons from 25.0 ha of areas of resource significance.
Materialna, ale niesamowita. Elektroniczna muzyka Andrzeja Markowskiego i SEPR w filmach fantastycznych
Authors: Topolski Jan
Published: August 2024

The text focuses on three early soundtracks by conductor-composer Andrzej Markowski (1924–1986) for sci-fi films: Milcząca gwiazda (dir. Kurt Maetzig, 1959), Wielka, większa i największa (dir. Anna Sokołowska, 1962) and Przekładaniec (dir. Andrzej Wajda, 1968). Electroacoustic sounds were created with the help of engineers Eugeniusz Rudnik and Krzysztof Szlifirski in the Polish Radio Experimental Studio. Very physical methods and means of their production contributed greatly to the potential of embodying unreal worlds and objects. The simultaneous birth of musical avant-garde and sci-fi cinema in Poland led to the cliché of illustrating these films with electroacoustic sounds, which produce the experience of „uncanniness" in the audience. A brief portrait of Markowski and a history of his film music output are then presented in a methodological framework, relying mainly on Michel Chion's notion of rendering. In the analyses that follow much space is dedicated to the comparison between sounds in the original novels (Stanisław Lem’s Astronauts and Jerzy Broszkiewicz’s Wielka, większa i największa) and their film adaptations. In the crucial scenes from Milcząca gwiazda the mysterious “reel” from Venus is musically decrypted in a laboratory; the “insect” probes’ tones embody liveliness and multitude, and the gurgling of “lava” causes ambiguous reactions. In Wielka, większa i największa the sound effects of spaceship, soundscape of Vega planet and modulated voices or concrete sounds create the affect of Uncanny (Ernst Jentsch). Eventually, in Przekładaniec electroacoustic music is associated with madness or illness, as happened in many other films from that time. However, Markowski’s innovative use of acoustic and electronic music made these three particularly remarkable.
Klasy eksperymentalne w szkołach powszechnych w Wilnie w okresie dwudziestolecia międzywojennego
Authors: Pękowska Marzena
Published: August 2024

The interwar period was characterized by an experimental movement in the field of educational methods. This movement was the result of postulates announced as part of the new education trend, stimulating an alternative and innovative approach to the didactic and educational work of the school. The publication presents the organization of teaching in experimental classes in elementary schools No. 22 and No. 7 in Vilnius in the years 1918-1939. School inspectors’ reports collected in Lithuanian Central State Archives in Vilnius were mainly used for this purpose.
Models of Education: Neoliberal, Conservative and Welfare State – the Case Study of Finland and Poland
Authors: Suwalska Arleta
Published: August 2024

The article addresses two distinct models of education: Finnish and Polish, taking into consideration the ways of financing education. The research aims to identify the characteristic features of the Polish and Finnish models of education and teachers’ professional status in Finland and Poland. The focus of the study was to analyze relations between the neoliberal and conservative policies in Poland and the welfare state policy in Finland. The next step was to identify how state economy is related to ways of teachers’ educational functioning in Finland and Poland. The paper reveals differing attitudes and patterns which characterize the Finnish and Polish models of education with consequences for teachers’ satisfactory functioning in their profession.
Gry i zabawy ruchowe na lekcjach wychowania fizycznego w edukacji wczesnoszkolnej z uwzględnieniem sytuacji trudnych – kilka przykładów z praktyki
Authors: Wojewoda Anna
Published: August 2024

Physical education lessons in grades 1-3 of primary school play an important role in the processes of upbringing and socialization. Due to the great need to move and relieve tension at this age, they are a kind of safety valve. During physical education classes, students interact with one another more often. During contact team games or games focused on competition, tensions often occur, personal space is violated, and the child’s emotions take over. This article presents three movement games:     a bricklayer, a wolf and seven kids, and piggy in the middle. Authentic difficult situations (such as aggression, escaping from the classroom, throwing objects) that occurred during physical education lessons are described here, and proven solutions based on the teacher’s own experience are presented. The examples provided are not a ready-made recipe for every difficult behavior, but they show how small steps can be calmed down or worked out with the appropriate cooperation of the student, peers, parents, specialists, and the teacher.
Postwar Mourning and Melancholy: Germany Year of Zero and Hiroshima Mon Amour
Authors: Chen Dandan
Published: August 2024

This paper focuses on two films, Germany Year Zero and Hiroshima Mon Amour, which serve as testimonies to the postwar status of Berlin and Hiroshima, offering magnificent topological touches of traumatized cities and profound insights into the intersection of cities and trauma. Through their narratives, these films intricately explore the interplay between the interiorized exterior and the exteriorized interior, the spatialization of the unspeakable, and the folding of memory into the very fabric of cinematic architecture. All these elements are complicatedly intertwined with the themes of melancholy, forgetting, and remembering, adding layers of depth to the cinematic exploration.
Antimicrobial, remineralization, and infiltration: advanced strategies for interrupting dental caries
Authors: Yang Qingyi , Li Fan , Ye Yangyang , Zhang Xu
Published: August 2024

Dental caries, driven by plaque biofilm, poses a major oral health challenge due to imbalance in mineralization and demineralization. The primary objective in caries management is to maintain biofilm homeostasis while facilitating the repair and regeneration of dental hard tissues, thus restoring both structural integrity and functionality of affected teeth. Though antimicrobial and remineralization approaches haven shown promise, their standalone utilization without concurrent bacterial control or rebalancing lacks an integrated strategy to effectively arrest caries progression. Furthermore, according to the principles of minimally invasive dentistry, treatment materials should exhibit high permeability to ensure optimal sealing of demineralized tooth surfaces. The concept of interrupting dental caries (IDC) has emerged as a holistic approach, drawing upon extensive research encompassing three pivotal techniques: antibacterial strategies, remineralization therapies, and infiltration mechanisms, all of which are indispensable components in combating the progression of dental caries. In this review, we provide a comprehensive overview of the mechanisms and applications of antibacterial, remineralization, and infiltration technologies within the context of caries management. Additionally, we summarize advanced materials that align with the IDC concept, aiming to offer valuable insights for designing next-generation materials adept at preventing or halting caries progression efficiently.
Computational study of cross-flow in entropy-optimized nanofluids
Authors: Li Shuguang , Abdullah Nermeen , Khan Umair , Zaib Aurang , Elattar Samia , Ishak Anuar
Published: August 2024

Nanofluids (NFDs) are becoming better understood as a result of substantial boost in thermal efficiency advances and the rate of energy exchange employed in requisite fuel dynamics and automotive coolants. Owing to its usage, computational scrutinization examines the cross-flow of an NFD past an expanding/contracting sheet with the impact of suction. In addition, the entropy and irregular generation/absorption effects are induced to compute/estimate the magnificent point of NFD flow. The innovative components of this study are Brinkman number, nanoparticle volume fraction, dimensionless temperature difference, expanding/contracting factor, irregular heat source/sink, and suction parameters. The boundary layers undergo a stream-wise process through expanding and contracting sheets. Also, the study makes use of numerical simulations to scrutinize the aspects of heat transport and cross-flow of NFDs. The fundamental partial differential equations of the current model are converted to ordinary differential equations by using similarity variables, and then they are exercised via the bvp4c approach. Therefore, parametric research has been used to frame the effects of embedded flow variables on the drag force, heat transfer rate, and entropy generation profiles. Multiple solutions are provided for a certain range of shrinking parameters as well as the mass suction parameter. The results suggest that the shear stress enhances due to suction

f

wa

{f}_{\text{wa}}

and nanoparticle volume fraction

φ

TiO

2

{\varphi }_{{\text{TiO}}_{2}}

, while the heat transfer accelerates due to

φ

TiO

2

{\varphi }_{{\text{TiO}}_{\text{2}}}

and heat source

(

A

b

⁎

,

B

b

⁎

>
0

)

({A}_{b}^{\ast },{B}_{b}^{\ast }\gt 0)

and decelerates due to heat sink

(

A

b

⁎

,

B

b

⁎

<
0

)

({A}_{b}^{\ast },{B}_{b}^{\ast }\lt 0)

. In addition, a favorable comparison with the literature that is already out there has been found, and it shows a great deal of similarities.
Influence of mica paper surface modification on the water resistance of mica paper/organic silicone resin composites
Authors: Wang Haisheng , Ge Heyi , Xu Junke
Published: August 2024

This study enhances the water resistance of mica paper/organic silicone resin composites through surface modification with 3-aminopropyltriethoxysilane (APTES). The Fourier-transform infrared spectroscopy and the X-ray photoelectron spectroscopy confirmed the formation of chemical bonds between APTES and mica. The results showed that at an optimal APTES concentration of 0.6%, the water diffusion coefficient decreased from 5.0 × 10−3 mm²/min to 2.7 × 10−3 mm²/min, and the permeability coefficient decreased from 5.71 × 10−4 mm²/min to 1.94 × 10−4 mm²/min, with a significant reduction in equilibrium water uptake. Additionally, the modified composites exhibited minimal mechanical strength loss after moisture aging, demonstrating excellent water resistance. The interface shear strength tests revealed a 28.6% increase in interfacial bonding strength after APTES modification. This study demonstrates the potential of silane coupling agents to enhance the performance of inorganic polymer composites, providing theoretical support for their industrial application.
γ-Inverse graph of some mixed graphs
Authors: Boulahmar Wafa , Ghanem Manal , Abudayah Mohammad
Published: August 2024

Let

G

G

be a graph. Then, the inverse graph

G

−
1

{G}^{-1}

of

G

G

is defined to be a graph that has adjacency matrix similar to the inverse of the adjacency matrix of

G

G

, where the similarity matrix is

±
1

\pm 1

diagonal matrix. In this article, we introduced a generalization of this definition that serves the mixed graphs where the definition applied for the

α

\alpha

-Hermitian adjacency matrices of mixed graphs. Furthermore, for a class of unicyclic graphs, we were able to find an inverse mixed graph for a graph

G

G

, where it was proven that

G

−
1

{G}^{-1}

does not exist.
Changing Attitudes? Investigating the Link between Couples’ Pandemic Behavior, Cognitive Dissonance, and Gender Role Attitudes in Germany
Authors: Firl Katrin
Published: August 2024

Research found that not only macro-level processes like cohort replacements foster gender role attitude (GRA) change, but also life events and changes in lived realities. Framing the COVID-19 pandemic as a ‘natural experiment’ allows to reduce endogeneity when examining the association between emerging cognitive dissonance and GRA change. Estimating asymmetrical fixed effects regressions, I investigate the influence of changes in the division of family labor on GRAs for respondents with no pre-pandemic attitude-behavior discrepancy, using pairfam waves 11 and 13. Indeed, changes in behavior for respondents who had aligned behaviors and attitudes before the pandemic can be associated with GRA adaptation: A change toward an egalitarian division of family labor during the pandemic can be associated with more egalitarian GRAs. Likewise, a change toward an inegalitarian division can be associated with less egalitarian GRAs. These findings support the usefulness of cognitive dissonance as one explanatory mechanism for intra-individual attitudinal change.
Wenn alles auf den Tisch kommt – Die Weltbeziehungen der Homesharer werden in der Küche verhandelt
Authors: Katzer Henrike , Janzing Malte , Henning Christoph , Oberthür Jörg , Rosa Hartmut
Published: August 2024

Ausgangspunkt unseres Beitrags ist die Beobachtung, dass Eigentumsverhältnisse mit je spezifischen Formen der Weltbeziehung verbunden sind. Um der Frage nachzugehen, ob und wie sich die Weltbeziehungen von Subjekten verändern, wenn Eigentumsverhältnisse in Bewegung geraten, untersuchen wir, ob sich in Praktiken und Erfahrungen des Homesharing Irritationen und Veränderungen der Ding-, Sozial- und Selbstbeziehungen beobachten lassen und welche Form und Richtung diese dabei annehmen. Als Fokus dienen uns die beobachtbaren, stets prekären, tentativen und temporären Vergemeinschaftungsprozesse, die sich beim Teilen des interpersonalen Nahraums ergeben. Auf Grundlage qualitativer Interviews mit Nutzenden von Homesharing-Plattformen zeigen wir, dass die Küche und Situationen des gemeinsamen Essens zentrale Ausgangspunkte für die Gestaltung der Gemeinschaftlichkeit darstellen und rekonstruieren drei Typen von Homesharern, die zwischen den Orientierungen von Professionalität und Familialität oszillieren.
Thermal Deformation Behavior of Bismuth-Containing Stainless Steel
Authors: Hu Shengde , Wang Yifeng , Wu Suming , Wang Xinyun , Li Lixin , Liu Sheng
Published: August 2024

In the process of thermoplastic processing, bismuth stainless steel is prone to cracking, leading to a high reject rate and even failure in production. To solve this problem and provide a feasible process for the actual production, the true stress–strain curves of the material were obtained by hot compression experiments. Because the thermal simulation system cannot automatically consider the temperature and stress variation of the specimen because of the heat of plastic deformation and the friction between the specimen and the tool, experimental errors were carefully corrected. A kind of exponential function is found to be suitable for describing the modified stress–strain relationship of the invested steel. Based on the dynamic material model and Murty criterion, the thermal processing diagram of the free-cutting austenitic stainless steel was established, and the stable and unstable regions of the hot working of the free-cutting austenitic stainless steel were given. Rolling tests showed that under the condition of the selected stable zone, no crack occurred in the section of the rolled piece. Microscopic analyses showed that the microstructure distribution of rolled parts by the non-instability zone process is relatively uniform, and there were fewer spherical and fusiform inclusions.