bluuebunny/crossref_metadata_2025 huggingface dataset:
A New Class of Irregular Packing Problems Reducible to Sphere Packing in Arbitrary Norms
Authors: Litvinchev Igor , Fischer Andreas , Romanova Tetyana , Stetsyuk Petro
Published: March 2024

Packing irregular objects composed by generalized spheres is considered. A generalized sphere is defined by an arbitrary norm. For three classes of packing problems, balance, homothetic and sparse packing, the corresponding new (generalized) models are formulated. Non-overlapping and containment conditions for irregular objects composed by generalized spheres are presented. It is demonstrated that these formulations can be stated for any norm. Different geometrical shapes can be treated in the same way by simply selecting a suitable norm. The approach is applied to generalized spheres defined by Lp norms and their compositions. Numerical solutions of small problem instances obtained by the global solver BARON are provided for two-dimensional objects composed by spheres defined in Lp norms to demonstrate the potential of the approach for a wide range of engineering optimization problems.
Explicit P1 Finite Element Solution of the Maxwell-Wave Equation Coupling Problem with Absorbing b. c.
Authors: Beilina Larisa , Ruas Vitoriano
Published: March 2024

In this paper, we address the approximation of the coupling problem for the wave equation and Maxwell’s equations of electromagnetism in the time domain in terms of electric field by means of a nodal linear finite element discretization in space, combined with a classical explicit finite difference scheme for time discretization. Our study applies to a particular case where the dielectric permittivity has a constant value outside a subdomain, whose closure does not intersect the boundary of the domain where the problem is defined. Inside this subdomain, Maxwell’s equations hold. Outside this subdomain, the wave equation holds, which may correspond to Maxwell’s equations with a constant permittivity under certain conditions. We consider as a model the case of first-order absorbing boundary conditions. First-order error estimates are proven in the sense of two norms involving first-order time and space derivatives under reasonable assumptions, among which lies a CFL condition for hyperbolic equations. The theoretical estimates are validated by numerical computations, which also show that the scheme is globally of the second order in the maximum norm in time and in the least-squares norm in space.
Editorial: S. N. Mergelyan’s Dissertation “Best Approximations in the Complex Domain” (Short Version)
Authors: Mergelyan Sergey , Matevossian Hovik
Published: March 2024

Preface by Hovik A [...]
Event-Triggered Consensus Control in Euler–Lagrange Systems Subject to Communication Delays and Intermittent Information Exchange
Authors: Ji Yunfeng , Li Wei , Wang Gang
Published: March 2024

In this paper, we investigate the consensus control problem of Euler–Lagrange systems which can be used to describe the motion of various mechanical systems such as manipulators and quadcopters. We focus on consensus control strategies, which are important for achieving coordinated behavior in multi-agent systems. The paper considers the key challenges posed by random communication delays and packet losses that are increasingly common in networked control systems. In addition, it is assumed that each system receives information from neighboring agents intermittently. Addressing these challenges is critical to ensure the reliability and efficiency of such systems in real-world applications. Communication delay is time-varying and can be very large, but should be smaller than some bounded constant. To decrease the frequency of control input updates, we implement an event-triggered scheme that regulates the controller’s updates for each agent. Specifically, it does not update control inputs at traditional fixed intervals, but responds to predefined conditions and introduces a dynamic consensus item to handle information irregularities caused by communication delays and intermittent information exchange. The consensus can be achieved if the communication graph of agents contains a spanning tree with the desired velocity as the root node. That is, all Euler–Lagrange systems need to obtain the desired velocity, directly or indirectly (via neighbors), to reach consensus. We establish that the Zeno behavior can be avoided, ensuring a positive minimum duration between successive event-triggered instances. Finally, we provide simulation results to show the performance of our proposed algorithm.
Abnormality and Strict-Sense Minimizers That Are Not Extended Minimizers
Authors: Fusco Giovanni , Motta Monica
Published: March 2024

We consider a constrained optimal control problem and an extension of it, in which the set of strict-sense trajectories is enlarged. Extension is a common procedure in optimal control used to derive necessary and sufficient optimality conditions for the original problem from the extended one, which usually admits a minimizer and has a more regular structure. However, this procedure fails if the two problems have different infima. Therefore, it is relevant to identify such situations. Following on from earlier work by Warga but adopting perturbation techniques developed in nonsmooth analysis, we investigate the relation between the occurrence of an infimum gap and the abnormality of necessary conditions. For the notion of a local minimizer based on control distance and an extension, including the impulsive one, we prove that (i) a local extended minimizer that is not a local minimizer of the original problem, and (ii) a local strict-sense minimizer that is not a local minimizer of the extended problem both satisfy the extended maximum principle in abnormal form. The main novelty is result (ii), as until now, it has only been shown that a strict-sense minimizer that is not an extended minimizer is abnormal for an ‘averaged version’ of the maximum principle.
Cardiac Magnetic Resonance and Cardiac Implantable Electronic Devices: Are They Truly Still “Enemies”?
Authors: Fogante Marco , Volpato Giovanni , Esposto Pirani Paolo , Cela Fatjon , Compagnucci Paolo , Valeri Yari , Selimi Adelina , Alfieri Michele , Brugiatelli Leonardo , Belleggia Sara , Coraducci Francesca , Argalia Giulio , Casella Michela , Dello Russo Antonio , Schicchi Nicolò
Published: March 2024

The application of cardiac magnetic resonance (CMR) imaging in clinical practice has grown due to technological advancements and expanded clinical indications, highlighting its superior capabilities when compared to echocardiography for the assessment of myocardial tissue. Similarly, the utilization of implantable cardiac electronic devices (CIEDs) has significantly increased in cardiac arrhythmia management, and the requirements of CMR examinations in patients with CIEDs has become more common. However, this type of exam often presents challenges due to safety concerns and image artifacts. Until a few years ago, the presence of CIED was considered an absolute contraindication to CMR. To address these challenges, various technical improvements in CIED technology, like the reduction of the ferromagnetic components, and in CMR examinations, such as the introduction of new sequences, have been developed. Moreover, a rigorous protocol involving multidisciplinary collaboration is recommended for safe CMR examinations in patients with CIEDs, emphasizing risk assessment, careful monitoring during CMR, and post-scan device evaluation. Alternative methods to CMR, such as computed tomography coronary angiography with tissue characterization techniques like dual-energy and photon-counting, offer alternative potential solutions, although their diagnostic accuracy and availability do limit their use. Despite technological advancements, close collaboration and specialized staff training remain crucial for obtaining safe diagnostic CMR images in patients with CIEDs, thus justifying the presence of specialized centers that are equipped to handle these type of exams.
Determination of Bile Acids in Canine Biological Samples: Diagnostic Significance
Authors: Németh Krisztián , Sterczer Ágnes , Kiss Dávid Sándor , Lányi Réka Katalin , Hemző Vivien , Vámos Kriszta , Bartha Tibor , Buzás Anna , Lányi Katalin
Published: March 2024

The comprehensive examination of bile acids is of paramount importance across various fields of health sciences, influencing physiology, microbiology, internal medicine, and pharmacology. While enzymatic reaction-based photometric methods remain fundamental for total BA measurements, there is a burgeoning demand for more sophisticated techniques such as liquid chromatography–tandem mass spectrometry (LC-MS/MS) for comprehensive BA profiling. This evolution reflects a need for nuanced diagnostic assessments in clinical practice. In canines, a BA assessment involves considering factors, such as food composition, transit times, and breed-specific variations. Multiple matrices, including blood, feces, urine, liver tissue, and gallbladder bile, offer insights into BA profiles, yet interpretations remain complex, particularly in fecal analysis due to sampling challenges and breed-specific differences. Despite ongoing efforts, a consensus regarding optimal matrices and diagnostic thresholds remains elusive, highlighting the need for further research. Emphasizing the scarcity of systematic animal studies and underscoring the importance of ap-propriate sampling methodologies, our review advocates for targeted investigations into BA alterations in canine pathology, promising insights into pathomechanisms, early disease detection, and therapeutic avenues.
Self-Sustaining Water Microdroplet Resonators Using 3D-Printed Microfluidics
Authors: Awerkamp Parker A. , Hill David , Fish Davin , Wright Kimi , Bashaw Brandt , Nordin Gregory P. , Camacho Ryan M.
Published: March 2024

Microdroplet resonators provide an excellent tool for optical studies of water, but water microdroplets are difficult to maintain outside a carefully controlled environment. We present a method for maintaining a water microdroplet resonator on a 3D-printed hydrophobic surface in an ambient environment. The droplet is maintained through a passive microfluidic system that supplies water to the droplet through a vertical channel at a rate equivalent to its evaporation. In this manner, we are able to create and passively maintain water microdroplet resonators with quality factors as high as 3×108.
Preparation, Characterization, and Bioactivities of Polysaccharide–Nano-Selenium and Selenized Polysaccharides from Acanthopanax senticosus
Authors: Li Xiaoli , Li Ying , Wang Xueyan , Zhang Rui , Xue Jiaojiao , Ding Yi , Chu Xiuling , Su Jianqing
Published: March 2024

Acanthopanax senticosus polysaccharide–nano-selenium (ASPS-SENPS) and A. selenopanax selenized polysaccharides (Se-ASPS) were synthesized, and their characterization and biological properties were compared. The acid extraction method was used to extract the polysaccharides of A. selenopanax, followed by decolorization using the hydrogen peroxide method and deproteinization based on the Sevage method, and the purification of A. senticosus polysaccharides (ASPS) was carried out using the cellulose DEAE-52 ion column layer analysis method. An A. senticosus polysaccharide–nano-selenium complex was synthesized by a chemical reduction method using ASPS as dispersants. The selenization of polysaccharides from A. selenopanax was carried out using the HNO3-Na2SeO3 method. The chemical compositions, scanning electron microscopy images, infrared spectra, and antioxidant properties of ASPS-SENPS and Se-ASPS were studied, and they were also subjected to thermogravimetric analysis. The results indicated that the optimal conditions for the synthesis of ASPS-SENPS include the following: when ASPS accounts for 10%, the ratio of ascorbic acid and sodium selenium should be 4:1, the response time should be 4 h, and the reaction temperature should be 50 °C. The most favorable conditions for the synthesis of Se-ASPS were as follows: m (Na2SeO3):m (ASPS) = 4:5, response temperature = 50 °C, and response time = 11.0 h. In the in vitro antioxidant assay, when the mass concentration of Se-ASPS and ASPS-SENPS was 5 mg/mL, the removal rates for DPPH free radicals were 88.44 ± 2.83% and 98.89 ± 3.57%, respectively, and the removal rates for ABTS free radicals were 90.11 ± 3.43% and 98.99 ± 1.73%, respectively, stronger than those for ASPS. The current study compares the physiological and bioactivity effects of ASPS-SENPS and Se-ASPS, providing a basis for future studies on polysaccharides.
Single-Step Synthesis and Characterization of Non-Linear Tough and Strong Segmented Polyurethane Elastomer Consisting of Very Short Hard and Soft Segments and Hierarchical Side-Reacted Networks and Single-Step Synthesis of Hierarchical Hyper-Branched Polyurethane
Authors: Stern Theodor
Published: March 2024

Polyurethane elastomers are among the most versatile classes of industrial polymers—typically achieved through a two-step synthesis of segmented block copolymers, comprising very long and soft segments that provide elasticity and significantly long and hard segments that provide strength. The present research focused on the design of a single-step synthesis of a new segmented polyurethane consisting of very short soft and hard segments, crosslinked by preferentially side-reacted hierarchical tertiary oligo-uret network structures, thus exhibiting significant strength, elasticity, and toughness. Despite the theoretically linear structure, both FTIR and solid-state 13C NMR spectroscopy analyses indicated the quasi-equal presence of urethane groups and tertiary oligo-uret structures in the resulting polymer, indicating a preferential consecutive side reaction mechanism. Thermal analysis indicated the significant crystallization of soft segments consisting of only four ethylene oxide units, which was, hereby, demonstrated to occur via an extended chain mechanism. Tensile mechanical properties included significant strength, elasticity, and toughness. Increasing the soft segment length led to a decreased tertiary oligo-uret secondary crosslinking efficacy. The preferential hierarchical side reaction mechanism was, hereby, further confirmed through the synthesis of a completely new type of hyper-branched polymer via diisocyanate and a mono-hydroxy-terminated reagent. The structure–property relations and reaction mechanisms demonstrated in the present research can facilitate the design of new polyurethanes of enhanced performance and processing efficacy for a variety of novel applications.
Recent Advancements in the Utilization of s-Block Organometallic Reagents in Organic Synthesis with Sustainable Solvents
Authors: Rodríguez-Álvarez María Jesús , Ríos-Lombardía Nicolás , García-Garrido Sergio E. , Concellón Carmen , del Amo Vicente , Capriati Vito , García-Álvarez Joaquín
Published: March 2024

This mini-review offers a comprehensive overview of the advancements made over the last three years in utilizing highly polar s-block organometallic reagents (specifically, RLi, RNa and RMgX compounds) in organic synthesis run under bench-type reaction conditions. These conditions involve exposure to air/moisture and are carried out at room temperature, with the use of sustainable solvents as reaction media. In the examples provided, the adoption of Deep Eutectic Solvents (DESs) or even water as non-conventional and protic reaction media has not only replicated the traditional chemistry of these organometallic reagents in conventional and toxic volatile organic compounds under Schlenk-type reaction conditions (typically involving low temperatures of −78 °C to 0 °C and a protective atmosphere of N2 or Ar), but has also resulted in higher conversions and selectivities within remarkably short reaction times (measured in s/min). Furthermore, the application of the aforementioned polar organometallics under bench-type reaction conditions (at room temperature/under air) has been extended to other environmentally responsible reaction media, such as more sustainable ethereal solvents (e.g., CPME or 2-MeTHF). Notably, this innovative approach contributes to enhancing the overall sustainability of s-block-metal-mediated organic processes, thereby aligning with several key principles of Green Chemistry.
The Role and Mechanism of Paeoniae Radix Alba in Tumor Therapy
Authors: Yang Yating , Yuan Ling , Wang Kaili , Lu Doudou , Meng Fandi , Xu Duojie , Li Weiqiang , Nan Yi
Published: March 2024

Tumors have a huge impact on human life and are now the main cause of disease-related deaths. The main means of treatment are surgery and radiotherapy, but they are more damaging to the organism and have a poor postoperative prognosis. Therefore, we urgently need safe and effective drugs to treat tumors. In recent years, Chinese herbal medicines have been widely used in tumor therapy as complementary and alternative therapies. Medicinal and edible herbs are popular and have become a hot topic of research, which not only have excellent pharmacological effects and activities, but also have almost no side effects. Therefore, as a typical medicine and food homology, some components of Paeoniae Radix Alba (PRA, called Baishao in China) have been shown to have good efficacy and safety against cancer. Numerous studies have also shown that Paeoniae Radix Alba and its active ingredients treat cancer through various pathways and are also one of the important components of many antitumor herbal compound formulas. In this paper, we reviewed the literature on the intervention of Paeoniae Radix Alba in tumors and its mechanism of action in recent years and found that there is a large amount of literature on its effect on total glucosides of paeony (TGP) and paeoniflorin (PF), as well as an in-depth discussion of the mechanism of action of Paeoniae Radix Alba and its main constituents, with a view to promote the clinical development and application of Paeoniae Radix Alba in the field of antitumor management.
Safety-Catch Linkers for Solid-Phase Peptide Synthesis
Authors: Noki Sikabwe , de la Torre Beatriz G. , Albericio Fernando
Published: March 2024

Solid-phase peptide synthesis (SPPS) is the preferred strategy for synthesizing most peptides for research purposes and on a multi-kilogram scale. One key to the success of SPPS is the continual evolution and improvement of the original method proposed by Merrifield. Over the years, this approach has been enhanced with the introduction of new solid supports, protecting groups for amino acids, coupling reagents, and other tools. One of these improvements is the use of the so-called “safety-catch” linkers/resins. The linker is understood as the moiety that links the peptide to the solid support and protects the C-terminal carboxylic group. The “safety-catch” concept relies on linkers that are totally stable under the conditions needed for both α-amino and side-chain deprotection that, at the end of synthesis, can be made labile to one of those conditions by a simple chemical reaction (e.g., an alkylation). This unique characteristic enables the simultaneous use of two primary protecting strategies: tert-butoxycarbonyl (Boc) and fluorenylmethoxycarbonyl (Fmoc). Ultimately, at the end of synthesis, either acids (which are incompatible with Boc) or bases (which are incompatible with Fmoc) can be employed to cleave the peptide from the resin. This review focuses on the most significant “safety-catch” linkers.
Hypophosphatemia after Start of Medical Nutrition Therapy Indicates Early Refeeding Syndrome and Increased Electrolyte Requirements in Critically Ill Patients but Has No Impact on Short-Term Survival
Authors: Schneeweiss-Gleixner Mathias , Haselwanter Patrick , Schneeweiss Bruno , Zauner Christian , Riedl-Wewalka Marlene
Published: March 2024

Refeeding syndrome (RFS) is a potentially life-threatening complication in malnourished (critically ill) patients. The presence of various accepted RFS definitions and the inclusion of heterogeneous patient populations in the literature has led to discrepancies in reported incidence rates in patients requiring treatment at an intensive care unit (ICU). We conducted a prospective observational study from 2010 to 2013 to assess the RFS incidence and clinical characteristics among medical ICU patients at a large tertiary center. RFS was defined as a decrease of more than 0.16 mmol/L serum phosphate to values below 0.65 mmol/L within seven days after the start of medical nutrition therapy or pre-existing serum phosphate levels below 0.65 mmol/L. Overall, 195 medical patients admitted to the ICU were included. RFS was recorded in 92 patients (47.18%). The presence of RFS indicated significantly altered phosphate and potassium levels and was accompanied by significantly more electrolyte substitutions (phosphate, potassium, and magnesium). No differences in fluid balance, energy delivery, and insulin requirements were detected. The presence of RFS had no impact on ICU length of stay and ICU mortality. Screening for RFS using simple diagnostic criteria based on serum phosphate levels identified critically ill patients with an increased demand for electrolyte substitutions. Therefore, stringent monitoring of electrolyte levels is indicated to prevent life-threatening complications.
Synbiotics in Oncology: A Scoping Review Protocol on Their Impact and Outcomes in Cancer Care
Authors: Belloni Silvia , Arrigoni Cristina , Ceruso Maria Helena , Giacon Chiara , Magon Arianna , Conte Gianluca , Arcidiacono Marco Alfredo , Caruso Rosario
Published: March 2024

Symptom management remains challenging in cancer care. Emerging from nutritional science, nutritional metabolomics has seen exponential growth over recent years, aiming to discern the relationship between dietary habits and health consequences. This protocol aims to present the rationale and methodology for conducting a scoping review to summarize the extent of evidence on synbiotics utilization in cancer symptom management among adults. The scoping review will be undertaken in accordance with the Joanna Briggs Institute (JBI) principles and the research process guided by the PRISMA 2020 scoping reviews extension. The following electronic databases will be searched from the inception: PubMed, Cinahl, Web of Science and Scopus. The authors expect to map the literature regarding the clinical outcomes, including patient-report measures and patient-experience measures, on which the effects of probiotics were tested, and identify potential gaps. This protocol presents a rigorous methodological approach to map the literature on the clinical outcomes that the utilization of synbiotics might improve. This analysis will shape future researchers to examine the efficacy of probiotics on specific clinical outcomes in oncology care. Nurses are uniquely positioned to influence cancer symptom management through the selection and use of appropriate interventions in the field of nutritional supplements, along with nutritional counseling.
Osteoprotective Effect of the Phytonutraceutical Ormona® on Ovariectomy-Induced Osteoporosis in Wistar Rats
Authors: do Nascimento Aline Lopes , Furtado Gabriel da Costa , Vilhena Vinicius Maciel , Carvalho Helison de Oliveira , Sales Priscila Faimann , Barcellos Alessandra Ohana Nery , de Maria Kaio Coutinho , Braga Francinaldo Sarges , da Silva Heitor Ribeiro , Bezerra Roberto Messias , Carvalho José Carlos Tavares
Published: March 2024

The phytonutraceutical Ormona® is a product composed of purified oil of Bixa orellana Linné, dry extract of Myrciaria dubia McVaugh, dry extract of Trifolium pratense L., and dry extract of Euterpe oleracea Mart. obtained using Evolve® technology. This study evaluated the effects of Ormona® on Wistar rats affected by ovariectomy-induced osteoporosis. Pre-treatment was conducted for 15 days before surgery and continued for a further 45 days after the surgical procedure. The experimental design consisted of five groups (n = 5): OVW: treated with distilled water (1 mL/kg, p.o); ADS: alendronate sodium (4 mg/kg p.o); EST: conjugated estrogen (2 µg/kg, p.o); ORM: Ormona® (20 mg/kg, p.o); ORM + EST: Ormona® (20 mg/kg, p.o) + conjugated estrogen (2 µg/kg, p.o). Biochemical and hormonal parameters of bone histopathology and trabecular and femoral diaphysis size were evaluated through scanning electron microscopy (SEM) and bone calcium quantification by atomic absorption spectrophotometry. The results show that ovariectomy caused bone alterations such as loss of femoral microarchitecture, decreased bone homeostasis parameters, and changes in the lipid profile. Estrogen supplementation reduced parameters such as cholesterol, LDL, and Ca2+ concentration. However, Ormona® showed higher serum estradiol levels (p < 0.01), effects on the lipid profile, including parameters that estrogen replacement and alendronate sodium did not affect, with an increase in HDL, and positive modulation of bone metabolism, increasing osteocytes and the presence of osteoblasts. Ormona®, therefore, produced better results than the groups treated with estrogen and alendronate sodium.
Current Perspectives on Biological Screening of Newly Synthetised Sulfanilamide Schiff Bases as Promising Antibacterial and Antibiofilm Agents
Authors: Coanda Maria , Limban Carmen , Draghici Constantin , Ciobanu Anne-Marie , Grigore Georgiana Alexandra , Popa Marcela , Stan Miruna , Larion Cristina , Avram Speranta , Mares Catalina , Ciornei Mariana-Catalina , Dabu Aura , Hudita Ariana , Galateanu Bianca , Pintilie Lucia , Nuta Diana Camelia
Published: March 2024

Growing resistance to antimicrobials, combined with pathogens that form biofilms, presents significant challenges in healthcare. Modifying current antimicrobial agents is an economical approach to developing novel molecules that could exhibit biological activity. Thus, five sulfanilamide Schiff bases were synthesized under microwave irradiation and characterized spectroscopically and in silico. They were evaluated for their antimicrobial and antibiofilm activities against both Gram-positive and Gram-negative bacterial strains. Their cytotoxic potential against two cancer cell lines was also determined. Gram-positive bacteria were susceptible to the action of these compounds. Derivatives 1b and 1d inhibited S. aureus’s growth (MIC from 0.014 mg/mL) and biofilm (IC from 0.029 mg/mL), while compound 1e was active against E. faecalis’s planktonic and sessile forms. Two compounds significantly reduced cell viability at 5 μg/mL after 24 h of exposure (1d—HT-29 colorectal adenocarcinoma cells, 1c—LN229 glioblastoma cells). A docking study revealed the increased binding affinities of these derivatives compared to sulfanilamide. Hence, these Schiff bases exhibited higher activity compared to their parent drug, with halogen groups playing a crucial role in both their antimicrobial and cytotoxic effects.
Leveraging Large Data, Statistics, and Machine Learning to Predict the Emergence of Resistant E. coli Infections
Authors: Hur Rim , Golik Stephine , She Yifan
Published: March 2024

Drug-resistant Gram-negative bacterial infections, on average, increase the length of stay (LOS) in U.S. hospitals by 5 days, translating to approximately $15,000 per patient. We used statistical and machine-learning models to explore the relationship between antibiotic usage and antibiotic resistance over time and to predict the clinical and financial costs associated with resistant E. coli infections. We acquired data on antibiotic utilization and the resistance/sensitivity of 4776 microbial cultures at a Kaiser Permanente facility from April 2013 to December 2019. The ARIMA (autoregressive integrated moving average), neural networks, and random forest time series algorithms were employed to model antibiotic resistance trends. The models’ performance was evaluated using mean absolute error (MAE) and root mean squared error (RMSE). The best performing model was then used to predict antibiotic resistance rates for the year 2020. The ARIMA model with cefazolin, followed by the one with cephalexin, provided the lowest RMSE and MAE values without signs of overfitting across training and test datasets. The study showed that reducing cefazolin usage could decrease the rate of resistant E. coli infections. Although piperacillin/tazobactam did not perform as well as cefazolin in our time series models, it performed reasonably well and, due to its broad spectrum, might be a practical target for interventions in antimicrobial stewardship programs (ASPs), at least for this particular facility. While a more generalized model could be developed with data from multiple facilities, this study acts as a framework for ASP clinicians to adopt statistical and machine-learning approaches, using region-specific data to make effective interventions.
Synthesis of Robust Full Poincaré Polarization States via Spatial Coherence Engineering
Authors: Zhang Ruihui , Zhang Ming , Dong Zhen , Wang Fei , Cai Yangjian , Chen Yahong
Published: March 2024

The full Poincaré (FP) beam, encompassing all possible polarization states in its beam cross-section, has demonstrated advantages in various applications. However, conventional FP beams are typically considered as spatially fully coherent, rendering them sensitive to disturbances in the propagation path and susceptible to speckle effects. In this work, we propose an alternative approach to synthesize the optical beam with a FP polarization state through the spatial coherence engineering of a partially coherent beam. In this process, the FP polarization state is initially encoded into the spatial coherence structure of the beam source. We demonstrate that during the encoding process, the vector nature of the beam transitions from the FP polarization state to the spatial coherence structure of the source. However, during the propagation of the partially coherent beam, the vectorness reverts to the polarization state, resulting in the re-emergence of the encoded FP polarization in the output plane. We illustrate that the synthesized FP polarization state, achieved through spatial coherence engineering, is highly robust against obstructions in the propagation path. Furthermore, we examine the effect of the spatial coherence area of the beam on the quality of the recovered FP polarization state. The findings of this work can have valuable applications in optical trapping and optical imaging in complex environments.
Inhibition of Potato Fusarium Wilt by Bacillus subtilis ZWZ-19 and Trichoderma asperellum PT-29: A Comparative Analysis of Non-Targeted Metabolomics
Authors: Hao Jianxiu , Wang Zhen , Zhao Yuanzheng , Feng Shujie , Cui Zining , Zhang Yinqiang , Wang Dong , Zhou Hongyou
Published: March 2024

Potato Fusarium Wilt is a soil-borne fungal disease that can seriously harm potatoes throughout their growth period and occurs at different degrees in major potato-producing areas in China. To reduce the use of chemical agents and improve the effect of biocontrol agents, the inhibitory effects of the fermentation broth of Bacillus subtilis ZWZ-19 (B) and Trichoderma asperellum PT-29 (T) on Fusarium oxysporum were compared under single-culture and co-culture conditions. Furthermore, metabolomic analysis of the fermentation broths was conducted. The results showed that the inhibitory effect of the co-culture fermentation broth with an inoculation ratio of 1:1 (B1T1) was better than that of the separately cultured fermentation broths and had the best control effect in a potted experiment. Using LC-MS analysis, 134 metabolites were determined and classified into different types of amino acids. Furthermore, 10 metabolic pathways had the most significant variations, and 12 were related to amino acid metabolism in the KEGG analysis. A correlation analysis of the 79 differential metabolites generated through the comprehensive comparison between B, T, and B1T1 was conducted, and the results showed that highly abundant amino acids in B1T1 were correlated with amino acids in B, but not in T.
Improved Approach for ab Initio Calculations of Rate Coefficients for Secondary Reactions in Acrylate Free-Radical Polymerization
Authors: Lugo Fernando A. , Edeleva Mariya , Van Steenberge Paul H. M. , Sabbe Maarten K.
Published: March 2024

Secondary reactions in radical polymerization pose a challenge when creating kinetic models for predicting polymer structures. Despite the high impact of these reactions in the polymer structure, their effects are difficult to isolate and measure to produce kinetic data. To this end, we used solvation-corrected M06-2X/6-311+G(d,p) ab initio calculations to predict a complete and consistent data set of intrinsic rate coefficients of the secondary reactions in acrylate radical polymerization, including backbiting, β-scission, radical migration, macromonomer propagation, mid-chain radical propagation, chain transfer to monomer and chain transfer to polymer. Two new approaches towards computationally predicting rate coefficients for secondary reactions are proposed: (i) explicit accounting for all possible enantiomers for reactions involving optically active centers; (ii) imposing reduced flexibility if the reaction center is in the middle of the polymer chain. The accuracy and reliability of the ab initio predictions were benchmarked against experimental data via kinetic Monte Carlo simulations under three sufficiently different experimental conditions: a high-frequency modulated polymerization process in the transient regime, a low-frequency modulated process in the sliding regime at both low and high temperatures and a degradation process in the absence of free monomers. The complete and consistent ab initio data set compiled in this work predicts a good agreement when benchmarked via kMC simulations against experimental data, which is a technique never used before for computational chemistry. The simulation results show that these two newly proposed approaches are promising for bridging the gap between experimental and computational chemistry methods in polymer reaction engineering.
Resveratrol-Loaded Polydimethylsiloxane–Silica Hybrid Materials: Synthesis, Characterization, and Antitumoral Activity
Authors: Viegas Sofia , Marinheiro Diogo , Bastos Verónica , Daniel-da-Silva Ana L. , Vieira Ricardo , Oliveira Helena , Almeida José Carlos , Ferreira Bárbara J. M. L.
Published: March 2024

In this work, hybrid materials within the polydimethylsiloxane–silica (PDMS–SiO2) system, synthesized via the sol–gel method, were developed and characterized for their potential to incorporate and release the bioactive compound resveratrol (RES). RES was incorporated into the materials with a high loading efficiency (>75%) using the rotary evaporator technique. This incorporation induced the amorphization of RES, resulting in enhanced solubility and in vitro release when compared to the free polyphenolic compound. The release profiles displayed pH dependence, exhibiting notably faster release at pH 5.2 compared to pH 7.4. The gradual release of RES over time demonstrated an initial time lag of approximately 4 h, being well described by the Weibull model. In vitro cytotoxicity studies were conducted on human osteosarcoma cells (MG-63), revealing a concentration-dependent decrease in cell viability for RES-loaded samples (for concentrations >50 µg mL−1).
The Use of Immobilised Enzymes for Lipid and Dairy Processing and Their Waste Products: A Review of Current Progress
Authors: Alzahrani Fawzih , Akanbi Taiwo O. , Scarlett Christopher J. , Aryee Alberta N. A.
Published: March 2024

The use of edible oils and fats in dairy products is becoming increasingly important in the food industry because of their complementary functional properties. Most of these products are produced using food-grade enzymes as processing aids because processes involving enzymes are considered mild and environmentally friendly for regulatory purposes. The poor stability and recovery of enzymes in their native state limit their performance, and to enhance their activity, stability, and reusability, enzymes are often immobilised—a process that involves attaching them to a solid support. Additionally, immobilisation enables enzymes to selectively target specific substrates or products, making them highly efficient. These features have led to the increased use of immobilised enzymes in dairy and lipid processing and enzymes have been used to produce a broad range of products such as whey protein concentrates and isolates, peptide–lipid conjugates, lipid concentrates, structured lipids, and human milk fat substitutes. Therefore, this article reviews the current progress on different enzyme preparations and their use in lipid and dairy processing. It also summarises opportunities in enzyme-catalysed valorisation of dairy and lipid waste streams with the ultimate goals of sustainable food production and reductions in waste.
Comparing the Aging Processes of PLA and PE: The Impact of UV Irradiation and Water
Authors: Wang Xucheng , Chen Jinxin , Jia Wenhao , Huang Kaibo , Ma Yini
Published: March 2024

The aging processes of microplastics (MPs) are prevalent in natural environments. Understanding the aging mechanisms of MPs is crucial for assessing their environmental behavior and potential risks. In this study, we selected polylactic acid (PLA) and polyethylene (PE) as representatives of biodegradable and conventional plastics, respectively, to examine changes in their physicochemical properties induced by water and UV light exposure. Laboratory aging resulted in significant fragmentation, characterized by cracks and pores on the surfaces, for both types of MPs, with PLA MPs exhibiting more severe changes, particularly under combined UV and water exposure. Notably, PLA MPs tended to become progressively smaller after aging, whereas PE MPs did not show significant size changes. Chemical analyses of aged MPs using micro-Fourier-transform infrared spectroscopy (FTIR) and X-ray photoelectron spectroscopy (XPS) revealed a substantial increase in the carbonyl index (CI) and oxygen content for PE, suggesting surface oxidation during photo-oxidation. Conversely, PLA MPs displayed a CI decrease, along with an oxygen content increase, indicating the breakdown of ester linkages in PLA and the formation of other oxidation products. Furthermore, we developed and optimized pyrolysis–gas chromatography–mass spectrometry (Py–GC–MS) methods to identify potential chemical degradation products of PE and PLA, considering their differing thermal stabilities. We observed a distinct trend regarding the peaks in the chromatogram of aged MPs and identified the typical oxidation and crosslinking products for PLA. Additionally, after the aging process, both PE and PLA exhibited a significant increase in organic carbon content, with the eluate containing submicron/nano-sized particles. This study provides a scientific foundation for a deeper understanding of the environmental aging mechanisms of various MPs, particularly in regards to the effects of UV irradiation and water exposure.
Comparison of Antioxidants to Increase the Oxidation Stability of Pyrolysis Oils of Three Plastics Using Iodine Value
Authors: Uebe Jochen , Lekaviciute Egle , Kryzevicius Zilvinas , Zukauskaite Audrone
Published: March 2024

Pyrolysis is an excellent method for recovering mixed and contaminated plastics that are no longer recyclable. Special attention must be paid to the stability of the fuel to avoid the formation of undesirable products. This can be achieved by additives such as antioxidants. In this study, high-density polyethylene, polypropylene, and polystyrene plastic waste are slowly pyrolyzed to a maximum of 470 degrees Celsius. A gasoline fraction (0–190 °C) and a diesel fraction (190–320 °C) are then obtained from these. Three antioxidants are added to these fractions: pyrocatechol, phenol, and freshly produced algal pyrolysis oil; the latter is described in the literature as containing particularly high levels of antioxidants. The oxidation stability of these mixtures and the change in the iodine number over time are measured using a newer method than the commonly used method of Wijs. Phenol improves the oxidation stability best, followed successively by algae pyrolysis oil and pyrocatechol. The oxidation stability of the gasoline fraction of the polypropylene pyrolysis oil with phenol is 49% higher than that of the same fraction without antioxidants.
Accommodation Strategies in Education: Exploring Jesuit Textbook Publication in Modern Shanghai
Authors: Mo Wei
Published: March 2024

This study examines the Jesuits’ significant contributions to China’s modernization through their involvement in textbook publication. It analyzes a recently discovered historical Catalogus of 1934 written in Latin to uncover insights. Specifically, it explores how the Jesuit T`ou-sè-wè Press in Shanghai responded to changes in education, society, and the interplay of religious and political forces. By investigating the Jesuits’ strategic adaptations in their educational and cultural pursuits, revised compilation and publishing methods, and proactive engagement with the dynamic environment, this study aims to provide a deeper understanding of their approach. Additionally, it investigates the nuanced accommodation strategies employed by the T`ou-sè-wè Press to navigate the complex challenges of the era.
Optimal Configuration of Omega-Kappa FF-SAR Processing for Specular and Non-Specular Targets in Altimetric Data: The Sentinel-6 Michael Freilich Study Case
Authors: Amraoui Samira , Guccione Pietro , Moreau Thomas , Alves Marta , Altiparmaki Ourania , Peureux Charles , Recchia Lisa , Maraldi Claire , Boy François , Donlon Craig
Published: March 2024

In this study, the full-focusing (FF) algorithm is reviewed with the objective of optimizing it for processing data from different types of surfaces probed in altimetry. In particular, this work aims to provide a set of optimal FF processing parameters for the Sentinel-6 Michael Freilich (S6-MF) mission. The S6-MF satellite carries an advanced radar altimeter offering a wide range of potential FF-based applications which are just beginning to be explored and require prior optimization of this processing. In S6-MF, the Synthetic Aperture Radar (SAR) altimeter acquisitions are known to be aliased in the along-track direction. Depending on the target, aliasing can be tolerated or may be a severe impairment to provide the level of performance expected from FF processing. Another key aspect to consider in this optimization study is the unprecedented resolution of the FF processing, which results in a higher posting rate than the standard SAR processing. This work investigates the relationship between posting rate and noise levels and provides recommendations for optimal algorithm configurations in various scenarios, including transponder, open ocean, and specular targets like sea-ice and inland water scenes. The Omega–Kappa (WK) algorithm, which has demonstrated superior CPU efficiency compared to the back-projection (BP) algorithm, is considered for this study. But, unlike BP, it operates in the Doppler frequency domain, necessitating further precise spectral and time domain settings. Based on the results of this work, real case studies using S6-MF acquisitions are presented. We first compare S6-MF FF radargrams with Sentinel-1 (S1) images to showcase the potential of optimally configured FF processing. For highly specular surfaces such as sea-ice, distinct techniques are employed for lead signature identification. S1 relies on image-based lineic reconstruction, while S6-MF utilizes phase coherency of focalized pulses for lead detection. The study also delves into two-dimensional wave spectra derived from the amplitude modulation of image/radargrams, with a focus on a coastal example. This case is especially intriguing, as it vividly illustrates different sea states characterized by varying spectral peak positions over time.
PrISM at Operational Scale: Monitoring Irrigation District Water Use during Droughts
Authors: Paolini Giovanni , Escorihuela Maria Jose , Bellvert Joaquim , Merlin Olivier , Pellarin Thierry
Published: March 2024

Efficient water management strategies are of utmost importance in drought-prone regions, given the fundamental role irrigation plays in avoiding yield losses and food shortages. Traditional methodologies for estimating irrigation amounts face limitations in terms of overall precision and operational scalability. This study proposes to estimate irrigation amounts from soil moisture (SM) data by adapting the PrISM (Precipitation Inferred from Soil Moisture) methodology. The PrISM assimilates SM into a simple Antecedent Precipitation Index (API) model using a particle filter approach, which allows the creation and estimation of irrigation events. The methodology is applied in a semi-arid region in the Ebro basin, located in the north-east of Spain (Catalonia), from 2016 to 2023. Multi-year drought, which started in 2020, particularly affected the region starting from the spring of 2023, which led to significant reductions in irrigation district water allocations in some of the areas of the region. This study demonstrates that the PrISM approach can correctly identify areas where water restrictions were adopted in 2023, and monitor the water usage with good performances and reliable results. When compared with in situ data for 8 consecutive years, PrISM showed a significant person’s correlation between 0.58 and 0.76 and a cumulative weekly root mean squared error (rmse) between 7 and 11 mm. Additionally, PrISM was applied to three irrigation districts with different levels of modernization, due to the different predominant irrigation systems: flood, sprinkler, and drip. This analysis underlined the strengths and limitations of PrISM depending on the irrigation techniques monitored. PrISM has good performances in areas irrigated by sprinkler and flood systems, while difficulties are present over drip irrigated areas, where the very localized and limited irrigation amounts could not be detected from SM observations.
Automatic Extraction of Martian Subsurface Layer from Radargrams Based on PDE Denoising and KL Filter
Authors: Shu Xin , Ye Hongxia
Published: March 2024

The polar regions of Mars, including the South and North Poles, are crucial for studying Martian climate and geological history, as they contain the largest reservoir of subsurface water ice. This study introduces a new approach for reflector detection, which includes radargram denoising to effectively enhance the signal of underground reflectors, peak detection to extract the positions of subsurface stratification from the radar echoes, and peak points connection to form continuous layers. The mapped enhancement denoising process involves a linear brightness adjustment and a fourth-order diffusion equation to enhance the signal of the subsurface layers for effective detection. The subsurface detection extracts the surface and subsurface peak points based on a peak detection algorithm, while using locally window-enhanced peak filtering and Kullback–Leibler (KL) divergence mapping to filter out non-stratified peak points. Finally, the layered connection process uses the proximity parameter to connect peak points in the same layer. Applied to multiple SHARAD (Shallow Radar) images at the Martian poles, this algorithm demonstrated a false detection rate below 5%. Compared to other methods, this method has a missed detection rate of less than 5% and, additionally, exhibits fewer discontinuities in layer connectivity. Therefore, this algorithm shows exceptional proficiency and applicability in analyzing the complex subsurface structures of the Martian polar regions.