bluuebunny/crossref_metadata_2025 huggingface dataset:
Reactogenicity and Immunogenicity Against MPXV of the Intradermal Administration of Modified Vaccinia Ankara Compared to the Standard Subcutaneous Route
Authors: Mazzotta Valentina , Piselli Pierluca , Cozzi Lepri Alessandro , Matusali Giulia , Cimini Eleonora , Esvan Rozenn , Colavita Francesca , Gagliardini Roberta , Notari Stefania , Oliva Alessandra , Meschi Silvia , Casetti Rita , Micheli Giulia , Bordi Licia , Giacinta Alessandro , Grassi Germana , Gebremeskel Tekle Saba , Cimaglia Claudia , Paulicelli Jessica , Caioli Alessandro , Gallì Paola , Del Duca Giulia , Lichtner Miriam , Sarmati Loredana , Tamburrini Enrica , Mastroianni Claudio , Latini Alessandra , Faccendini Paolo , Fontana Carla , Nicastri Emanuele , Siddu Andrea , Barca Alessandra , Vaia Francesco , Girardi Enrico , Maggi Fabrizio , Antinori Andrea
Published: December 2024

Background: The recent resurgence of mpox in central Africa has been declared a new public health emergency of international concern (PHEIC) requiring coordinated international responses. Vaccination is a priority to expand protection and enhance control strategies, but the vaccine’s need exceeds the currently available doses. Intradermal (ID) administration of one-fifth of the standard modified vaccinia Ankara (MVA-BN) dose was temporarily authorized during the 2022 PHEIC. Studies conducted before 2022 provided evidence about the humoral response against the vaccinia virus (VACV) after vaccination but not against the mpox virus (MPXV). Moreover, no data are available on the T-cell response elicited by MVA-BN administered subcutaneously or intradermally. Methods: We compare the two vaccine administration routes according to reactogenicity (n = 943) and immunogenicity (n = 225) of vaccine recipients attending INMI Spallanzani hospital during the 2022 vaccination campaign in Rome, Italy. Results: We found that the ID route elicited higher titers of MPXV-specific IgG (mean difference of 0.26 log2, p = 0.05) and nAbs (0.24 log2, p = 0.08) than the subcutaneous (SC) route one month after the complete vaccination cycle. At the same time, no evidence for a difference in cellular response was found. Conclusions: MVA-BN was globally well tolerated despite higher reactogenicity for the ID than the SC route, especially for the reactions at the local injection site. The ID dose-sparing strategy was proven safe and immunogenic and would make vaccination available to more people. Our data support the current WHO recommendation of using the ID route in low–medium-income countries (LMIC), although response data in people infected with the new 1b clade are urgently needed.
Mapping the Incidence of Infestation by Neoechinorhynchus buttnerae (Acanthocephala) Parasitizing Colossoma macropomum Raised in Fish Farms and the Relationship with Zooplankton Ostracods and Copepods
Authors: Perez Pedroti Vinicius , Vieira Dantas Filho Jerônimo , Bezerra de Mira Átila , de Lima Pinheiro Maria Mirtes , Temponi Santos Bruna Lucieny , Garcez Costa Sousa Raniere , Braitenbach Cavali Jucilene , da Rosa Prado Ed Johnny , de Vargas Schons Sandro
Published: December 2024

This study investigated the abundance of zooplankton copepods and ostracods taxonomic groups in fish farms in Rondônia’s Vale do Jamari and Centro-Leste microregions during the rainy and dry seasons. It also analyzed the correlation between zooplanktons abundance and the presence of acanthocephalan parasites. Conducted in 41 fish farms between November 2021 and September 2023, the study included water, zooplankton, and fish samples from 196 Colossoma macropomum. The results showed that 95% of the farms had fish infected with Neoechinorhynchus buttnerae, with varying parasitism levels. Georeferencing revealed higher parasite densities in the municipalities of Ariquemes, Monte Negro, Machadinho do Oeste, and Buritis (Vale do Jamari), as well as Urupá, Ji-Paraná, Ouro Preto do Oeste, and Teixeirópolis (Centro-Leste), with clusters of heat islands in the latter group. Water quality parameters were suitable for raising C. macropomum. The presence of ostracods and copepods could serve as indicators of parasitic infestations, highlighting the importance of monitoring zooplankton and parasite communities. This approach is valuable for detecting changes in artificial ecosystems, such as fish farms, which could lead to significant long-term effects.
Parameter Estimation of Nonlinear Structural Systems Using Bayesian Filtering Methods
Authors: Erazo Kalil
Published: December 2024

This paper examines the performance of Bayesian filtering system identification in the context of nonlinear structural and mechanical systems. The objective is to assess the accuracy and limitations of the four most well-established filtering-based parameter estimation methods: the extended Kalman filter, the unscented Kalman filter, the ensemble Kalman filter, and the particle filter. The four methods are applied to estimate the parameters and the response of benchmark dynamical systems used in structural mechanics, including a Duffing oscillator, a hysteretic Bouc–Wen oscillator, and a hysteretic Bouc–Wen chain system. Based on the performance, accuracy, and computational efficiency of the methods under different operating conditions, it is concluded that the unscented Kalman filter is the most effective filtering system identification method for the systems considered, with the other filters showing large estimation errors or divergence, high computational cost, and/or curse of dimensionality as the dimension of the system and the number of uncertain parameters increased.
Community-Based Farming Water Resource Management and Important Factors for Adaptation Practices in Terai, Nepal
Authors: Karki Sharada , Yokota Shigehiro
Published: December 2024

Driven by the growing frequency of flood risks, this study focused on farming water resource management (FWRM) as an ecosystem-based solution. Despite its significance, there are limited studies investigating paddy farmers’ community-based adaptations (CBAs) for managing diverse farming water resources at a micro-spatial level, particularly within multidimensional communities. This study aims to bridge this gap and focuses on how community diversity and household characteristics impact farmers’ adaptation to different CBA methods. We conducted a household questionnaire survey in floodplain paddy farming communities in Kawasoti Municipality, Nepal, based on cultural, socioeconomic, and settlement diversity. The questionnaire was subjected to farmers’ CBAs for integrated FWRM and multiple structural and nonstructural adaptation measures for irrigation and rivers. The results showed that farmer participation varied across community groups. To understand the most important associated factors within community diversity and household attributes to adopt different water resources, the most adopted structural measures of water flow management (54%) from irrigation and buffer zone vegetation (54%) from rivers were analyzed. We used the Chi-squared Automatic Interaction Detector model, which suggests that water accessibility associated with community diversity, landholding, and water intake is important to improve farmers’ participation in irrigation management. However, for river management, community diversity, which relates to location in relation to a river and is associated with household income and farmland distance, is an important factor.
Network of Nitrifying Bacteria in Aquarium Biofilters: An Unfaltering Cooperation Between Comammox Nitrospira and Ammonia-Oxidizing Archaea
Authors: Godzieba Martyna , Hliwa Piotr , Ciesielski Slawomir
Published: December 2024

Nitrification plays a crucial role in aquatic ecosystems and in the biofilters used in fish farms. Despite their importance, the role of canonical nitrifiers, comammox bacteria, and archaea has not yet been sufficiently investigated. The aim of this study was to characterize the microbiome of the external canister biofilter in a freshwater fish aquarium, with particular focus on the role of comammox Nitrospira and their competition with other nitrifiers. To achieve this, a comprehensive approach combining metagenome sequencing and co-occurrence network analysis was used to study the interactions between microorganisms in portable biofilter. The fish were subjected to a changing feeding regime that affected the ecological relationships and abundance of different microbial taxa. The results showed the presence of two types of nitrifiers in the biofilter: comammox Nitrospira and ammonia-oxidizing archaea (AOA). Five comammox Nitrospira genomes were reconstructed, with comammox clade B being the most abundant with an average abundance of 7.8 ± 0.4%. In addition, two families of archaea were identified: Nitrosopumilaceae and Nitrososphaeraceae, with an average abundance of 4.3 ± 0.4%. Heterotrophs were also abundant in the bacterial community, particularly in the genera Actinomycetota, Planctomycetota, and Pseudomonadota. Network analysis indicated competitive interactions between comammox and heterotrophs, whereas no competition was observed between comammox and AOA. The predominance of comammox Nitrospira, and AOA over canonical nitrifiers emphasizes their better adaptation to oligotrophic environments. This study highlights the importance of competition within the biofilter microbiome and the role of ecological interaction networks, which can contribute to the optimization of water purification systems in RASs.
Comprehensive Analysis of Transient Flow Pattern and Radial Force Characteristics Within Centrifugal Pumps Under Variable Frequency Speed Regulation
Authors: Tan Linwei , Niu Jianxun , Shi Weidong , Zhao Miaomiao , Gao Song , Yang Yang , Zuo Zilei , Wang Tao , Li Hui
Published: December 2024

This study investigates the transient behavior of a single-blade centrifugal pump under variable frequency speed regulation, with the objective of enhancing both pump efficiency and operational stability under variable frequency conditions. By integrating numerical simulations, external characteristic tests, and Particle Image Velocimetry (PIV) flow field experiments, the research provides a comprehensive analysis of the dynamic performance of the pump. The accuracy of the numerical simulations is first validated through a comparison between CFD results and experimental data, both at rated and variable speeds. This study then explores the transient external performance, internal flow patterns, and radial force characteristics of the pump under various speed-change schemes. In the process of acceleration, the variation trend of the centrifugal pump head and speed is basically the same, and Scheme 3 shows better stability; Scheme 2 minimizes the fluctuation of shaft power; with the increase in speed, the pressure and flow field in the pump will appear to be unstable. In the deceleration process, the Scheme 3 head fluctuates less, the change in shaft power is the most stable, and the more uniform pressure distribution and stable flow field can be maintained. The radial force increases with the increase in speed, but the degree of radial force fluctuation is different among different schemes. These findings offer valuable insights into the dynamic performance of centrifugal pumps under variable speed conditions and provide a foundation for optimizing both pump design and operational strategies.
Qualitative Assessment of Hazardous Gas Emissions from Sewage Sludge-Derived Biochar
Authors: Syguła Ewa , Leśniak Małgorzata , Bobak Łukasz , Koziel Jacek A. , Białowiec Andrzej
Published: December 2024

Approximately 10 million megagrams of sewage sludge is produced each year in the European Union alone. To date, options to utilize sewage sludge are limited. Local regulations and sludge characteristics strictly determine waste management options. Thermal disposal methods are recommended for highly contaminated sludge. Pyrolyzed sewage sludge generates biochar that can be used as a value-added agricultural product or as an alternative fuel. The biochar production itself carries the risk of emitting harmful compounds. Unfortunately, these important safety considerations are rarely addressed in the literature. This research investigates the mechanistic effects of the storage headspace-to-biochar volume ratio and stored biochar headspace ventilation on hazardous gas emissions. Five hazardous organic compounds were emitted by biochar. However, based on this initial proof-of-the-concept research, we could not derive conclusive trends for the effects of the headspace-to-biochar volume ratio or air exchanges in the biochar headspace. Further research, which is broader in scope (feedstock type, pyrolysis conditions), should be carried out. Nevertheless, caution should be exercised when designing biochar storage, aiming to lower the risk of occupational exposure to hazardous gas emissions. Monitoring air pollutants, tracking the highest permissible concentrations and workers’ exposure, and using personal protective equipment are recommended.
A Tractor Work Position Prediction Method Based on CNN-BiLSTM Under GNSS Signal Denial
Authors: Hu Yangming , Xu Liyou , Yan Xianghai , Chang Ningjie , Wan Qigang , Wu Yiwei
Published: December 2024

In farmland environments where GNSS signals are obstructed, such as forested areas or in adverse weather conditions, traditional GNSS/INS integrated navigation systems suffer from positioning errors and instability. To address this, a model-assisted integrated navigation system is proposed, combining Convolutional Neural Networks (CNN) and Bidirectional Long Short-Term Memory (BiLSTM) networks. The CNN-BiLSTM model is trained under normal GNSS conditions and used to predict positioning when GNSS signals are interrupted, effectively replacing GNSS to ensure stable and accurate navigation. Experimental validation is conducted using field data from tractor simulations. The results show that, during a 100-s GNSS denial, the CNN-BiLSTM model reduces the average position error by 79.3% compared to pure inertial navigation and by 5.4% compared to traditional LSTM. In a 30-s GNSS denial, the average position error is reduced by 41% compared to inertial navigation and 6.2% compared to LSTM. The model maintains positioning accuracy within 3% of the GNSS/INS output under normal conditions, demonstrating its feasibility and effectiveness. This approach offers a promising solution for autonomous tractor navigation in GNSS-denied agricultural environments, contributing to precision agriculture.
Değişen Konuşma Dili
Authors: Can Dila , Yıldız Derya
Published: December 2024

Dil, yapı itibariyle canlı bir varlıktır. Kimi diller günümüze ulaşamadan yok olup gitmiş kimi diller ise yakın zamanlarda başka dillerden doğarak yeni bir dil hâlini almıştır. Ama şu bir gerçektir ki bütün dünya dilleri yaşadıkları müddetçe değişime uğramaktadır. Bu değişimler yazılı ve sözlü olarak kendini göstermektedir. Konuşma dilinde ortaya çıkan değişimler, yazılı dilden çok daha hızlı bir biçimde dönüşmektedir. Türkçe konuşma dilinde gerçekleşen değişimi gözlemlemenin en doğru yolu elimizde bulunan medya araçları (ses kayıt dosyaları, arşiv videoları, sosyal platformlar, yayınlanan görüntüler) ile veri toplamak ve bu verilerin ışığında karşılaştırma yaparak Türkçenin değişimini detaylı analiz etmektir. 1968 yılından itibaren TRT Arşiv’de bulunan konuşmalar değişen konuşma dili üzerinde 50 yıllık bir karşılaştırma imkânı sunmaktadır. Araştırma, yazar söyleşileri ve konferansları ile sınırlandırılmıştır. Araştırmada TRT Arşiv’de yer alan beş söyleşi ile 2022 yılı TEDx yazar konferansları söylem çözümlemesi ile analiz edilmiştir. Konuşmalar, söylem analizi kapsamında konuşmanın fiziksel unsurları bakımından detaylı olarak irdelenmiştir. Elde edilen bulgulara göre en çok değişiminin kelimelerde olduğu görülmüştür. Eski dönemlerdeki konuşmalarda kullanılan pek çok kelimenin günümüzdeki konuşmalarda yer almadığı belirlenmiştir. Günümüzdeki yazarların konuşmalarında mizahın ve ikilemelerin daha çok yer aldığı tespit edilmiştir. Günümüzde konuşmalar oldukça hızlıyken geçmişte daha sakin ve yavaş bir tonda konuşulmaktadır. Geçmiş dönemdeki konuşmaların daha çok oturma biçiminde yapıldığı ve daha nazik bir dil tercih edildiği belirlenmiştir. Günümüzde ise konuşmalar daha çok ayakta ve daha samimi bir üslupla gerçekleştirilmektedir. Eski dönemdeki konuşmaların konularının doğrudan sanat ve edebiyat olduğu günümüzdeki konuşma konularının ise bu birikimlerin hayatımıza nasıl anlamlı bir fark getirmeye evrildiği görülmüştür. Eski dönemdeki konuşmalarda daha uzun cümle yapılarının tercih edildiği belirlenmiştir.
Okul Öncesi Dönemde Travma Sonrası Stres Tepkilerini Belirleme Ölçeği (Öğrretmen Formu): Ölçek Geliştirme Çalışması
Authors: Akyüz Uçar Gökce Aysu , Çetin Bayram
Published: December 2024

Travmaya doğrudan veya dolaylı yoldan maruz kalan bireylerde fiziksel, bilişsel, davranışsal ve duygusal belirtiler ile ortaya çıkarak kişilerin uyum sorunları yaşamasına neden olan semptomlar travma sonrası stres olarak tanımlanabilir. Bu stres tepkilerini tanımlamak ve düzeyini belirlemek üzere geliştirilmiş pek çok ölçme aracı olmasına rağmen, okul öncesi dönemdeki çocukların öğretmen gözlemlerine dayalı olarak travma tepkilerini değerlendirmeye imkân tanıyan ölçme araçlarının eksikliğinden bahsetmek mümkündür. Okul Öncesi Dönemde Travma Sonrası Stres Tepkilerini Belirleme Ölçeği (Öğretmen Formu) okul öncesi kurumlarda sınıf rehber öğretmenlerinin travmatik olay sonrası rehberlik servisine öğrenci yönlendirmede kullanarak öğrencinin farklı tepki türleri ve genel stres durumu ile veri sağlaması amacıyla geliştirilmiştir. Nicel araştırma yöntemine göre hazırlanan bu araştırmanın çalışma grubunu olasılıksız örnekleme yoluyla Gaziantep ilindeki 200 anaokulu öğrencisi oluşturmaktadır. 39 maddeden oluşan ilk form için 15 uzmandan görüş alınarak kapsam geçerlik indeksi hesaplanmış ve bu veriler doğrultusunda madde sayısı 27’ye düşürülmüştür. Elde edilen verilerin normallik sınaması Kolmorov-Smirnov testi ile güvenirlik değeri ise Cronbach Alpha katsayısı ile açıklanmıştır. Açıklayıcı Faktör Analizi (AFA) sonucunda ölçek formu 21 madde ve “Duygusal Tepkiler”, “Uyarılmışlık”, “Davranışsal Tepkiler”, “Psikolojik Tepkiler” ve “Bilişsel Tepkiler” alt boyutlarından oluşmuştur. Analizlerde alt boyutların birbiri ile ilişkisi bulunmuş aynı zamanda yapılan Doğrulayıcı Faktör Analizi (DFA) AFA sonuçlarını doğrulamıştır. Ölçeğin güvenirlik katsayısı .94 olarak hesaplanmış ve ölçüt geçerliği amacıyla kullanılan ölçek ile korelasyon sonuçları pozitif yönde anlamlı görülmüştür.
Ortaokul Öğrencilerinin Üstbilişsel Farkındalıklarının İncelenmesi
Authors: Demir Selvi , Demir Yılmaz
Published: December 2024

Üst biliş, bireyin öğrenme ve hafıza yeteneğini, başarabileceği öğrenme görevlerinin neler olduğunu gerçekçi bir şekilde ortaya koyması, hangi öğrenme stratejilerinin öğrenme açısından daha etkili olup hangilerinin işe yaramadığını bildirmesi, yeni öğrenme görevleri için uygulanabilir bir yol planı oluşturması, öğrenme stratejilerini yeni koşullara uygun hâle getirmesi ve mevcut bilgi durumunu izlemesi gibi bilgi ve becerileri içerdiği için öğrenme ve düşünme süreçleri açısından oldukça önemlidir. Dolayısıyla öğrenme sürecindeki önemli etkenlerden birini de üst bilişsel farkındalık oluşturmaktadır. Buradan hareketle bu araştırmanın amacı çocukların üst bilişsel farkındalıklarını belirlemek ve bu farkındalıklarını cinsiyet, yaş, akademik başarı, anne ve baba eğitimi durumu, sahip olunan ve okunan kitap sayısı, internette ve televizyonda geçirilen süre değişkenleri bağlamında incelemektir. Bu doğrultuda tarama desenine göre tasarlanan araştırmanın örneklem grubunu 2024-2025 eğitim öğretim yılının güz döneminde ortaokul kademesinde öğrenim gören 638 çocuk oluşturmaktadır. Araştırmanın verileri “Kişisel Bilgi Formu” ile “Üstbilişsel Farkındalık Ölçeği (ÜBFÖ-B)” kullanılarak toplanmıştır. Verilerin normal dağılıma sahip olması, istatistiksel analizlerde parametrik testlerin kullanılmasını sağlamıştır. Araştırma sonucunda ortaokula devam eden öğrencilerin üst bilişsel farkındalıklarının yüksek düzeyde olduğu belirlenmiştir. Ayrıca öğrencilerin üstbilişsel farkındalıklarının, incelenen değişkenlerinin tamamına göre istatistiki anlamda anlamlı bir farklılık sergilediği tespit edilmiştir.
LEGAL AND APPLIED ASPECTS OF DIGITALISATION OF HIGHER PHARMACEUTICAL EDUCATION IN UKRAINE: IMPLEMENTATION OF THE EUROPEAN EXPERIENCE
Authors: Manchenko Oksana
Published: December 2024

The digital development of the healthcare system in Ukraine is supported by the state and society, as evidenced by the adoption of several important regulatory acts, including the Law of Ukraine “On Medicines”, the Strategy for the Development of Medical Education in Ukraine, and several orders of the Cabinet of Ministers of Ukraine, including “On Approval of the Concept for the Development of Digital Competencies and Approval of the Action Plan for its Implementation”, “On Approval of the Concept for the Development of Electronic Healthcare”. An example of a successful implementation of digital tools in the healthcare system is eHealth, which currently includes several IT systems, registries, digital services, and digital products, the most famous of which is the electronic healthcare system (EHS), a key information and communication system that contains medical data on the health of 35 million Ukrainians and unites most medical institutions and pharmacies in the country into a single digital medical space. Thanks to the UHS, Ukrainian citizens can use digital services such as e-prescriptions, e-referrals, e-medical certificates, etc. The implementation of the state policy on digitalization of higher pharmaceutical education in modern Ukraine is based on the development of digital technologies and covers all specialties. This necessitates overcoming the existing limitations in the development of digital transformation in higher pharmaceutical education, and the formation of future masters of pharmacy digital competencies at the stage of acquiring the future profession. Thus, the use of digital technologies in the educational process should improve the quality of students’ self-study work, stimulate the development of research activities of both teachers and students, create a new didactic and methodological framework for the activities of institutions that would meet the requirements of the digitalisation process, and contribute to the intensification of the educational process under martial law in Ukraine.
MEDIA INTERPRETATIONS, ETHICAL PERSPECTIVES ON THE CONCEPTUALIZATION OF THE “EARTH WITHOUT BORDERS” PROJECT
Authors: Korniienko Svitlana
Published: December 2024

Media reality has acquired an ontological status and has become the foundation of a new cultural landscape, including the landscape of the Earth. Humans project their desires, avoiding the deeper understanding of the phenomenon of Earth, as the Earth serves as a platform for media presentations. This contemplation deepens the divide between humans and the Earth. The Earth takes on the meaning of an artificial reality, diminishing the sense of responsibility. The Earth’s space, in the context of modern technology, which creates a new dimension of existence, acquires a configuration that can no longer be accurately mapped, rendering the question of open or closed borders irrelevant. This refers to the emergence of virtual landscapes that replace the objective reality of Earth’s existence. This raises the issue of ethical attitudes toward the Earth in the context of transformational changes within media reality, which pushes Earth’s future projects into the background of an illusory world.
PSYCHOLOGISM OF MODERNIST PROSE AS A REALIZATION OF NATIONAL IDENTITY
Authors: Zinovieva Kateryna
Published: December 2024

The article highlights a deep reflection of the subjective world of a person, which is primarily a topical issue that involves an emphasis on the internal perception of reality, that is, multidimensional personalities characterized by the search for new forms and methods of artistic expression are studied and highlighted. Ukrainian modern prose depicts a national identity that struggles for existential reality and self-identification, thus reflecting the entire conflictual reality of the social unit in relation to the psychological drama in the characters' cultural lives. Often, the psychological role of a subject in the social life of a community leads to internal struggles under cultural pressure.
Conclusions. In this work, based on the analysis, explores the national identity and cultural identity of the Ukrainian people, which are reflected in the works of the modernist period of literature and focus on the internal conflicts of subjects struggling for personal identity. The renewed form of thinking and psychological consciousness of the subject provide further strength for the development of Ukrainian literature in Europe. After all, the perception of reality experienced by the characters of the works is reflected in accordance with their psychological states. Therefore, spiritual search, the pursuit of individualism, and national identity are new rules that help to reflect the overall picture of the national consciousness in the issue of the realization of the psychologism of modernist prose in the Ukrainian question of national literature.
General Practice chest x-ray rate is associated with earlier lung cancer diagnosis and reduced all-cause mortality: a retrospective observational study
Authors: Bradley Stephen H. , Neal Richard , Callister Matthew , Cornwell Benjamin , Hamilton William , Abel Gary A. , Shinkins Bethany , Hubbard Richard , Barclay Matthew
Published: December 2024

Background: Evidence on whether general practice rates of investigation in symptomatic patients using chest x-ray (CXR) affects outcomes is equivocal. Aim: Determine if there is an association between rates of general practice (GP) requested CXR and lung cancer outcomes. Design and setting: Retrospective observational study (England) Methods: Cancer registry data for patients diagnosed with lung cancer 2014-2018 was linked to data on GP CXRs 2013-2017. Stage at diagnosis (I/II vs III/IV) and one and five year survival (conditional on survival to one year) following diagnosis was reported by quintile of CXR rate of patients’ GP with adjustment for population differences (age, smoking, prevalence of COPD and heart failure, ethnicity and deprivation) and by unadjusted category (low, medium, high). Results: 192,631 patient records and CXR rates for 7,409 practices were obtained. Practices with highest quintile CXR rate had fewer cancers diagnosed at stage III/IV compared to lowest quintile (OR=0.87, 95% CI 0.83-0.92, p<0.001). The association was weaker for high unadjusted CXR category (OR=0.94, 95% CI 0.91-0.97). For the highest adjusted quintile HRs for death within one year and five years were 0.92 (0.90-0.95), p<0.001) and 0.95 (95% CI 0.91-0.99, p=0.023) respectively. For the high unadjusted CXR category the HR for one year survival was 0.98 (95% CI 0.96-0.99, p=0.004) with no association demonstrated for five year survival. Conclusions: Patients registered at GPs with higher CXR use have a favourable stage distribution and slightly better survival. This supports use of CXR in promoting earlier diagnosis of symptomatic lung cancer in general practice
Diplomasi Digital Dalam Mengembangkan UMKM Go Global Go Digital di Kepulauan Riau
Authors: Putri Rizqi Apriani , Swastiwi Anastasia Wiwik , Aleksa Nabila Zazkia Zikra
Published: December 2024

Fenomena globalisasi saat ini mengalami berbagai transformasi digital terhadap peningkatan akses informasi, kesejahteraan masyarakat, inovasi dan produktivitas. Perkembangan teknologi di era digitalisasi ini memberikan perubahan cukup penting dalam kehidupan bermasyarakat, bahkan diplomasi digital dimanfaatkan untuk negosiasi. Diplomasi digital dapat memberikan informasi public serta membangun relasi antar negara dalam Hubungan Internasional. Penelitian ini bertujuan untuk mendapatkan pemahaman tentang diplomasi digital meningkatkan UMKM Go Global Go Digital ditengah perkembangan arus teknologi saat ini serta inovasi ekonomi di Masyarakat. Metode penelitian yang digunakan yaitu deskriptif kualitatif yaitu data dikumpulkan akan dianalisis dari sumber data primer dan sekunder seperti buku, artikel, publikasi, laporan serta jenis publikasi lainnya yang relevan dalam penelitian ini. Pada akhir tahun 2019, dunia dilanda oleh Pandemi Covid-19 yang menyebabkan pembatasan mobilitas antar negara. Akibat pandemic Covid-19 ini, terjadinya peningkatan pemanfaatan teknologi digital. Pemerintah memanfaatkan teknologi digital ini untuk meningkatkan UMKM dengan slogan Go Global Go Digital yang telah dicanangkan oleh Bank Indonesia sejak tahun 2020. Penerapan teknologi digital yang mampuni dapat meningkatkan UMKM di pasar global. Kepulauan Riau yang memiliki wilayah strategis yang berbatasan dengan negara tetangga dapat dimanfaatkan dalam pengembangan UMKM menembus pasar global dengan memperluas kerjasama Cross Border Payment Connectivity. Penelitian ini diberdampak terhadap diplomasi digital secara komprehensif. Kata Kunci — Diplomasi Digital, Globalisasi, UMKM
EMPOWERMENT OF CADRES ON CHILD DEVELOPMENT THROUGH THE USE OF THE FIRST 1000 DAYS OF LIFE CALENDAR IN THE PASIRKLIKI COMMUNITY HEALTH CENTER WORK AREA, NORTH CIMAHI
Authors: Rosita Ayu , Ruhmawati Tati
Published: December 2024

Introduction Nutritional problems occur in every life cycle, starting from the womb (foetus), infants, children, adults and old age. The period of the first two years of life is a critical period, because during this time there is rapid growth and development. One of the nutritional problems suffered by toddlers is stunting, which is a short or very short body condition that occurs due to malnutrition and repeated diseases for a long time in the fetal period to the first 2 years of a child's life (Ministry of Health of the Republic of Indonesia, 2016).
Methods activities are carried out in the Posyandu Pasirkaliki cadre group, Cimahi Utara District, Cimahi City. The activity plan is in the form of education about child growth and development, checking growth and development in toddlers and assisting stunting toddlers. Objectives Provide education and mentoring, with the target of increasing knowledge and skills on growth and development monitoring detection and early detection of stunting in cadres.
The results showed a significant increase in the mean score of participants' knowledge from 83.39 to 87.14. The increase in knowledge is supported by the ability of cadres to improve Early Detection of Stunting skills.
Estudio interlaboratorio para las mediciones de composición nutricional de Quinoa (Chenopodium quínoa Willd) en Laboratorios Chilenos
Authors: Gutiérrez Vargas María Natalia , Sandoval Riqulme Soraya , Muñoz Villagrán Marcelo
Published: December 2024

Los ensayos de intercomparación permiten evaluar resultados de ensayos reportados por distintos laboratorios sobre una misma muestra, de manera simultánea y así determinar los desempeños analíticos.Las características nutricionales de la quinoa son reconocidas como superiores a las de otros productos similares, ahí la importancia de medir con certeza sus características poniendo a la quinua dentro de la vanguardia en la lucha por mejorar la nutrición sobre todo de la población infantil.La composición nutricional de los alimentos es establecida a través del análisis proximal, que incluye la determinación del contenido de humedad, proteína cruda (nitrógeno total), fibra cruda, lípidos crudos y cenizas.  El Laboratorio del Instituto de Salud Pública (ISP), miembro de la Red Nacional de Metrología de Chile (RNM), organizó con el apoyo de la Oficina de Estudios y Políticas Agrarias (ODEPA) un ensayo interlaboratorio para la determinación de nutrientes en un material de referencia certificado de quínoa y de este modo evaluar a los laboratorios que realizan ensayos de quinoa en nuestro país. El material contaba con valores certificados para humedad, cenizas, proteínas y minerales.En el interlaboratorio participaron 9 laboratorios nacionales. Los valores asignados para la evaluación de desempeño se basaron en los valores certificados del material. Las puntuaciones z-score revelaron 78% de resultados satisfactorios para humedad y proteínas, 80% de resultados satisfactorios para potasio, cobre y zinc, 100% de satisfactoriedad para la determinación de cenizas, un 60% para hierro y un 50% para cadmio. Las medias obtenidas excluidos los valores anómalos y las medianas obtenidas de los participantes fueron consistentes con el valor certificado para humedad, proteínas y minerales. De este modo, el interlaboratorio permitió conocer que para la mayoría de los analitos se obtuvo un desempeño satisfactorio por sobre el 75%, revelando las necesidades de mejoras analíticas en el análisis de hierro y cadmio.
Consecuencia de la exposición adolescente a cannabis: una mirada desde la ciencia básica
Authors: Fuentealba Jose
Published: December 2024

La adolescencia es un estado del desarrollo ontogénico caracterizada por una transición fisiológica y conductual gradual, que va desde la niñez hasta la adultez, e incluye importantes cambios hormonales asociados al inicio de la pubertad. Durante este periodo, los adolescentes muestran una mayor sensibilidad a estímulos gratificantes y una predisposición incrementada a realizar conductas riesgosas, en comparación con los adultos. Como consecuencia, existe una alta probabilidad de que se inicie el uso exploratorio de diversas drogas de abuso, incluyendo el alcohol, la nicotina y la marihuana. De hecho, estudios del Servicio Nacional para la Prevención y Rehabilitación del Consumo de Drogas y Alcohol (SENDA) muestran una mayor prevalencia anual de uso de marihuana en la población escolar (18.8 %) en comparación con la población general (10.9%). En este contexto es importante destacar que durante la adolescencia el cerebro esta en un constante proceso de crecimiento y especialización con el fin de moldear nuestra conducta y responder a las demandas externas. Sin embargo, es también un periodo donde el cerebro esta mas expuesto a los efectos deletéreos de las drogas abuso, predisponiendo fuertemente a desordenes psiquiátricos durante la adultez, incluyendo esquizofrenia, depresión y adicción a drogas.
From Icons to Identities
Authors: Simpson Logan
Published: December 2024

The study explores the integration of visual cultural elements in emerging scripts and the motivations driving their development. By examining ten scripts from across the globe, the research identifies four main types of visual cultural elements: common cultural icons and images, influences from traditional art forms, elements from Indigenous knowledge systems, and traditional body art forms. The exploration suggests that integrating these elements may enhance script acceptance within communities, fostering a stronger connection with users. Additionally, the study explores five primary motivations for script development: resistance towards dominant groups, unification of marginalised groups, expression of cultural identity, language preservation, and recuperation of literacy. While visual cultural elements may impact script acceptance, the motivations behind script development also provide insights into historical and contemporary trends in global script innovation. The study suggests that incorporating visual cultural elements in script design could play a significant role in promoting cultural continuity and supporting language preservation.
Ecologically sustainable social policy as a challenge for the 21st century. The perspective of climate change consequences in Poland
Authors: Koczur Wiesław , Lorek Agnieszka
Published: December 2024

The central objective of the article is to determine the basic links between social and environmental policies in the context of sustainable development and to evaluate the challenges of environmental issues for particular social policy sectors. The primary research method applied in the following article was a systematic review of the available literature on the subject, thematic reports, statistical data and legal acts. The main areas of concern analysed are the identification of the most significant challenges facing social policy in the 21st century in the context of environmental protection and of the most significant effects of climate change and other environmental threats on sectoral social policies (population and family policy, education policy, labour market policy, social security policy, health care and housing policy), along with the directions of necessary changes. Currently, environmental issues are still greatly neglected in social policy debates. The article presented here is a comprehensive attempt to assess the environmental and climate challenges for social policy. Moreover, it points out the necessary directions for change.
FARKLI ESANSİYEL YAĞLARLA HAZIRLANMIŞ BALIK (Luciobarbus esocinus (Heckel, 1843)) KÖFTELERİNİN MİKROBİYOLOJİK VE DUYUSAL KALİTESİ
Authors: Polat Yunus , Şeker Engin , Karaton Kuzgun Nermin
Published: December 2024

Bu çalışmada, nane (Spearmint sp.) ve kekik (Origanum spp.) esansiyel yağları ilave edilmiş Luciobarbus esocinus eti ile üretimi yapılan balık köftelerinin soğuk muhafazada mikrobiyolojik ve duyusal kalitesi araştırılmıştır. Üç farklı deneysel köfteler 4±1°C’de muhafaza altına alındı ve muhafaza günlerinde analizleri yapıldı. Deneysel köfte örneklerinin mikrobiyolojik olarak toplam mezofilik aerob bakteri (TMAB), Toplam psikrofil aerob bakteri sayısı (TPAB), toplam maya-küf, Laktik asit bakteri sayısı ve koliform bakteri sayıları belirlendi. Ayrıca çalışmada hazırlanan ürünlerin duyusal olarak değerlendirmeleri yapılırken görünüş, renk, lezzet, koku, genel beğeni bakımından incelendi.
Deneysel örneklerin muhafazanın başlangıç aşamasında toplam mezofilik aerobik bakteri sayısı 3.12±0.66-4.35±0.93 kob/g arasında belirlenirken, psikrofil bakteri sayısı balık köftesi örneklerinin depolama başlangıcında toplam laktik asit bakterisi sayısının 3,90±0,29-4,20±0,24 kob/g arasında olduğu belirlendi. Depolama başlangıcındaki maya- küf sayısı 4,60±1,22, 4,25±1,22 ve 4,73±0,99 kob/g (A, B, ve C gruplarında sırasıyla) olarak belirlendi. İncelenen örneklerde depolama sırasında Toplam psikrofil bakteri sayısı günler arası farklılığın istatistiksel açıdan önemli olduğu belirlenmiştir (p
İlkokul Dördüncü Sınıf Öğrencilerinin Dijital Okuryazarlık Düzeyleri ve Yazma Becerilerinin İncelenmesi
Authors: Bitir Tufan , Duran Erol
Published: December 2024

Çalışmanın amacı, ilkokul dördüncü sınıf öğrencilerinin dijital okuryazarlık düzeyleri ile yazı yazma becerileri arasındaki ilişkinin incelenmesidir. Çalışmada, hem tarama modeli hem de durum çalışması desenleri kullanıldığı için çalışma sıralı açıklayıcı karma model olarak tasarlanmıştır. Araştırmanın çalışma grubu uygun örnekleme yöntemi ile belirlenen ve 2022-2023 eğitim öğretim yılında Aydın ilindeki bir ilkokulda öğrenim gören 115 dördüncü sınıf öğrencisi ve bu öğrencilerin sınıf öğretmenleri olan beş öğretmenden oluşmaktadır. Araştırmada üç farklı veri toplama aracı kullanılmıştır. Bu araçlar; “Dijital Okuryazarlık Ölçeği”, “Yazı Değerlendirme Formu” ve “Yarı Yapılandırılmış Görüşme Formu”dur. Araştırmada öncelikle ilkokul dördüncü sınıf öğrencilerinin dijital okuryazarlık düzeyini belirlemek için “Dijital Okuryazarlık Ölçeği” kullanılmıştır. Dijital okuryazarlık ölçeğinden elde edilen veriler SPSS programı yoluyla incelenerek araştırmanın betimsel istatistik sonuçlarına ulaşılmıştır. Ardından dijital okuryazarlık düzeyleri düşük olarak belirlenen 37 ve yüksek olarak belirlenen 29 öğrencinin defterleri Millî Eğitim Bakanlığının ilkokul dördüncü sınıf öğrencileri için belirlediği yazı değerlendirme kriterleri göz önünde bulundurularak içerik analizi tekniği ile incelenmiştir. Defterlerin içerik analizi ile incelenmesi sonucunda öğrencilerin yazılarının dördüncü sınıf yazı kurallarına uygun olup olmadığı belirlenmiştir. Son olarak dijital okuryazarlık düzeyleri düşük ve yüksek olarak belirlenen öğrencilerin öğretmen-leriyle yarı yapılandırılmış görüşme formu ile görüşmeler gerçekleştirilmiştir. Görüşmeler ses kayıt cihazına kaydedilmiş ve daha sonra öğretmenlerin görüşlerindeki benzerlik ve farklılık içeren ifadeler tespit edilmiş, birbiriyle ilişkili olan ifadeler gruplanarak doğrudan ifadelerle temalandırılarak tablolaştırılmıştır. Çalışmada veri toplama aracı olarak kullanılan dijital okuryazarlık ölçeğinden elde edilen veriler doğrultusunda öğrencilerin dijital okuryazarlık durumları “düşük, orta ve yüksek” düzey olarak belirlenmiştir. Ayrıca öğrencilerin defterleri içerik analizi ile incelenerek düşük düzeyde dijital okuryazar öğrencilerin yazı yazma kurallarına uygun yazılar yazdıkları; yüksek düzeyde dijital okuryazar öğrencilerin ise yazı yazma kurallarına uygun yazılar yazmadıkları tespit edilmiştir. Bu tespitlerle ilgili öğretmenlerle görüşmeler yapılmış ve öğretmenler genel olarak araştırma bulgularını destekler görüşler belirtmişlerdir.
The Podium of Injustice Set Up in Social Memory: The Case of Uğur Mumcu
Authors: Över Vecdi Olgaç
Published: December 2024

When concerned people feel justice has not been achieved, they try to find ways to adapt, and a fundamental tool in their process of adaptation is social memory. In this context, this article focuses on the assassination of Uğur Mumcu and the communities that commemorate him, and seeks to reveal how the perception of injustice dominant in human groups builds structures in social memory. On 24 January 1993, Uğur Mumcu, one of Turkey's well-known journalists and writers, was assassinated, and despite the decades that have passed since his murder, some communities have continued to commemorate him. In these events, rituals, symbols, discourses, memory spaces, some of which are unique to Uğur Mumcu commemorations, have emerged, and a calendar, sentiment and organization of the events have emerged. In the process, social memory was instrumentalized by those who were deprived of the restorative or, in other words, soothing aspect of justice. The perception of injustice creates a ground that nourishes the identities of social actors and a ground on which they can disclose those identities. This ground derives its legitimacy from the social justification of the search for justice and can be conceptualized as a "podium of injustice." Through the activities, performances, attitudes and rituals practiced here, communities display their identities to themselves and to society. In this framework, the discourse on the search for justice and on Uğur Mumcu as a social figure have acquired new meanings and functions in the process. As a result, society uses social memory in an effort to adapt to injustice, and over time, the same social memory turns into a space where groups can make their identities visible. This article attempts an "ethnography of injustice" on the basis of social memory, and an analysis of the reflections and social structures created by the perception of injustice in the social life of communities.
Sosyal Medyada Güç İstenci Savunma Mekanizmaları İle Veri İlişkisini Dijital Yerliler Üzerinden İncelemek
Authors: Tan Hakan , Şenkal Yelda
Published: December 2024

Güç istenci savunma mekanizmaları ile kişilerin sosyal medyada takip ettiği hesaplardaki takipçi, beğeni, yorum ve etkileşim verileri arasında anlamlı bir ilişki vardır. Kişiler sosyal medyayı benliğin güç istenci savunma mekanizmalarına katkı sağladığı için kullanmaktadır. Veri, bağlamdan yoksun anlamsız bir noktadır. Bağlam takip edilen kişinin ya kalıtsal ve kişisel ya konumsal ve formal ya da etkileyebilme kapasitesine sahip olduğu güçtür. Güç istencinin yaratılmasında veri sosyal medya kullanıcıları üzerinde etkilidir. Bu araştırma, sosyal medyada gerçek benliğin (ego’nun) güç istenci savunma mekanizması olarak açıklanan Kalıtsal ve Kişisel, Etkileyebilme Kapasitesi, Konumsal ve Formal ve Sahte Benliğin Güç İstenci Savunma Mekanizmaları ile sosyal medyadaki verilerin (beğeni, takipçi, yorum ve etkileşim sayısı) kullanıcılar üzerindeki etkisini incelemeyi ve açıklamayı amaçlamaktadır. Çalışmada iletişim ve sosyal bilimlerin araştırma, yöntemlerinden kantitatif (nicel) araştırma yöntemi ve model olarak da survey (tarama) kullanılmaktadır. Araştırmanın bulgularına göre gerçek benliğin sağlıklı çabaları olarak açıklanan Doğallık, Görkemli Görüntü, Görünmek, Hayal ve Güç İstenci Savunma Mekanizmaları ile sosyal medyadaki veriler arasında anlamlı bir ilişki bulunmaktadır. Sosyal medyadaki takipçi, beğeni ve etkileşim sayıları güç istenci savunma mekanizmalarını daha kompakt ve kullanışlı bir hale getirmektedir.
Development of Maternal Gatekeeping Scale for Mothers with Preschool Aged Children
Authors: Dönmez Özlem , Ural Ozana
Published: December 2024

Family is the first social group in which child interacts. Both mothers and fathers have an impact on the development of children. However, participation of mothers and fathers in the development of the child may vary according to the cultural attributions given to mother and father roles and spousal relationship. The aim of the research is to develop a valid and reliable measuring instrument to investigate the maternal gatekeeping of mothers and examine maternal gatekeeping behaviors of mothers according to demographic variables. In this research “Causal Comparative Research Method” was used. The sample of the research was randomly selected 524 mothers of 36-72 from 24 preschools of 6 districts. The data was collected via “Maternal Gatekeeping Scale” and “Family Information Form” developed within the study. Reliability and validity analysis of the scale were conducted, and it is seen that the scale is comprised of 5 sub-scales and 57 items. As the results of the comparison tests, there are differences found according to duration of maternal care, mothers’ working status, working hours, education levels, ages, fathers’ working hours, education levels, whether there is a support in childcare, number of children, school type, and duration of marriage. The results of the study were discussed considering the relevant literature.
Barreras percibidas por los directivos y docentes para el desarrollo de la investigación científica en una universidad paraguaya
Authors: Díaz Gamarra Marisa , Viveros de Cabello Guiomar , Villasanti Torales Ulises , Méndez Romero Julieta , González Vázquez Gloria Sebastiana , López Britez Gladys Rosalva
Published: December 2024

RESUMEN
La investigación es esencial ya que permite desarrollar, evaluar el conocimiento disciplinar, lo que ha constituido en una ciencia. Es una función ineludible para sus profesionales, sin embargo, es poco valorada por las instituciones y poco exigida en el actuar de la profesión. El objetivo de la investigación fue de describir las barreras percibidas por los directivos y docentes para el desarrollo de la Investigación científica en la Universidad Nacional de Caaguazú. Se realizó un estudio de enfoque cualitativo fenomenológico, humanista, se enmarcó en el paradigma fenomenológica, se llevó a cabo entre los meses febrero a marzo del año 2023 en las distintas Unidades Académicas de la Universidad Nacional de Caaguazú. Participaron 7 directores de investigación y 12 docentes incluido docentes investigadores y docentes de áreas técnicas y/o prácticas. Las barreras identificadas por los directores para el avance de la investigación científica en su unidad académica son diversas. Sin embargo, existen factores que favorecen el desarrollo investigativo en las facultades de la Universidad Nacional de Caaguazú. Entre ellos, se destacan la exigencia de las agencias evaluadoras de realizar investigaciones, la incentivación mediante la participación en congresos, la presentación y premiación de trabajos, y una política institucional que otorga créditos a los docentes investigadores. Además, el compromiso del personal, la existencia de una revista científica y una red de investigadores, la actitud proactiva de los estudiantes y la promoción de docentes investigadores contribuyen significativamente, al igual que el deseo de contribuir al bienestar social.
Palabras claves: investigación, influencia en la investigación, directivos, docentes, brechas.