bluuebunny/crossref_metadata_2025 huggingface dataset:
Exame ultrassonográfico como apoio diagnóstico em caso de ruptura diafragmática em cão - relato de caso
Authors: Morais Juliana do Nascimento Pola de , Martins Junior Raul , Medeiros Fernanda Peres de
Published: January 2025

Relata-se neste trabalho o caso de um paciente da espécie canina, macho, meia idade, sem raça definida, resgatado da rua,apresentando caquexia, hiporexia e respiração abdominal. No primeiro atendimento foi realizadohemograma, teste sorológico 4 dx e raio-x de tórax, no qual notou-se a presença de acúmulo de líquido em espaço pleural. Foi realizado exame ultrassonográfico complementar do tórax, sendo notado a presença do parênquima esplênico,lobos craniais do fígado, vesícula biliar e estômago, além de efusão pleural, previamente observada na avaliação radiográfica. Paciente foi submetido a toracocentese imediataguiada pelo ultrassom, onde foi retirado 650 ml de líquido intra-torácico. Posteriormente foi encaminhado para correção cirúrgica da ruptura de diafragmática, porém veio à óbito no trans-operatório.
Изучение хронической токсичности нового миорелаксанта на белых крысах
Authors: Ямалова Г.Р.
Published: January 2025

Для отлова животных применяют миорелаксанты периферического действия, которые отличаются по составу, механизму действия, способности расслаблять различные группы мышц, также по эффективности воздействия при разных способах введения. В отделении токсикологии ФГБНУ «ФЦТРБ-ВНИВИ» получен препарат с миорелаксирующим действием. Важным этапом доклинической оценки безопасности нового лекарственного препарата является изучение его хронической токсичности, направленное на выявление возможности обратимости желаемого токсического эффекта, что и определило цель данного исследования. Целью исследования являлось изучение хронической токсичности разработанного миорелаксанта на белых крысах. Хроническую токсичность оценивали на 36 беспородных белых крысах обоего пола, весом от 170 до 220 г. Всего было сформировано три группы животных. Животным первой контрольной группы внутримышечно вводили воду для инъекций, второй – 1/10 смертельной дозы (ЛД50) миорелаксант (0,26 мг/кг массы тела), третьей – полуторакратную дозу от 1/10 ЛД50 препарата, что соответствовало 0,39 мг/кг массы тела. Результаты исследований продемонстрировали, что парентеральное длительное введение миорелаксанта не оказывает существенного влияния на массу и температуру тела лабораторных животных, не вызывает негативного воздействия на гематологические и биохимические показатели крови белых крыс. Таким образом, препарат с миорелаксирующим действием не обладает хронической токсичностью при длительном введении белым крысам.

For trapping animals, peripheral muscle relaxants are used, which differ in composition, mechanism of action, ability to relax various muscle groups, as well as in the effectiveness of exposure with different methods of administration. A drug with a muscle relaxant effect was developed in the Department of Toxicology of the FSBSI «FCTRBS-ARRVI». An important stage in the preclinical evaluation of the safety of a new drug is the study of its chronic toxicity, aimed at identifying the possibility of reversibility of the desired toxic effect, which determined the purpose of this study. The aim of the reserach was to study the chronic toxicity of the developed muscle relaxant in white rats. Chronic toxicity was evaluated on 36 outbred white rats of both sexes, weighing from 170 to 220 g. In total, three groups of animals were formed. The animals of the first control group were intramuscularly administered with water for injections, the second - 1/ 10 of the lethal dose (LD50) of muscle relaxant (0.26 mg/kg of body weight), the third - a one-and-a half dose of 1/10 LD 50 of the drug, which corresponded to 0.39 mg/kg of body weight. The results of the studies demonstrated that parenteral long-term administration of a muscle relaxant neither significantly affected the body weight and temperature of laboratory animals, nor caused a negative effect on hematological and biochemical parameters of the blood of white rats. Thus, the drug with a muscle relaxant effect does not have chronic toxicity when administered for a long time to white rats.
Blue Innovation, Value Creation, and Decision-making on Digital Performance and Sustainability
Authors: Renaldo Nicholas , Junaedi Achmad Tavip , Suhardjo Suhardjo , Veronica Kristy , Augustine Yvonne , Musa Sulaiman , Cecilia Cecilia
Published: January 2025

This study proposed model framework introduces a novel approach by positioning Blue Innovation as a primary driver of Value Creation and Decision-Making, which in turn mediate the relationship between Digital Performance and Sustainability. In this quantitative research, data will be collected using a structured questionnaire. The sample size will be 155 respondents. This study uses Structural Equation Modeling (SEM) analysis to analyze the influence of independent, intervening, and control variables on the dependent variable. The findings provide significant insights into how these variables interact and influence one another, summarized as blue innovation significantly enhances digital performance, value creation has a strong positive impact on digital performance, decision-making significantly improves digital performance, blue innovation positively influences sustainability, value creation cannot directly increase sustainability, decision-making has a significant positive impact on sustainability, digital performance significantly enhances sustainability, blue innovation increases sustainability through digital performance, value creation indirectly increases sustainability through digital performance, decision-making positively influences sustainability through digital performance.
Analysis of User Satisfaction with the Mnet Plus Application Using the End-User Computing Satisfaction Method
Authors: Gunawan Witjaksono  , Nanda Silva
Published: January 2025

The development of the global entertainment industry, especially K-pop, has driven innovation in digital applications. Mnet Plus, a mobile-based application, is designed to enhance user experience with various interactive features. Mnet Plus created a communication platform that provides an experience for global users to enjoy K-pop content. However, in its use, there are still several problems that make users less satisfied with the application. This issue is important to address because user satisfaction is the main indicator of an application's success and can influence loyalty and continued use. This research aims to determine the level of user satisfaction and the factors influencing it on the Mnet Plus application. This research uses a quantitative approach and the End User Computing Satisfaction (EUCS) method with five variables, namely content, accuracy, format, ease of use, and timeliness. Data collection was carried out by distributing questionnaires to users of the Mnet Plus application and then processing it using the SPSS 25 program for further analysis. The results of the analysis that was carried out show that of the five hypotheses that were partially tested, two hypotheses were rejected, namely the content and format variables. Simultaneously, the five variables have a significant effect on user satisfaction of the Mnet Plus application. The practical implication of these findings is the need for application developers to prioritize technical performance improvements, interface simplification, and feature timeliness.
THE CONTRIBUTION OF ISLAMIC SPIRITUAL EXTRACURRICULAR ACTIVITIES AND SCHOOL ENVIRONMENTAL SUPPORT IN THE FORMATION OF STUDENTS' SPIRITUAL INTELLIGENCE
Authors: Supriyadi Agus , Samsudin Mohamad Aso , Eriyanto Eriyanto
Published: January 2025

Spiritual intelligence is essential for students in this generation because it influences the development of attitudes such as values, morality, and self-awareness. This study investigates how extracurricular activities like Dhuha prayer, Islamic studies, princesses, and others might enhance students' educational experiences by developing their spiritual intelligence. This study employs qualitative methodologies with a descriptive-analytic methodology. Thus, the researcher will explore the field to see how spiritual activities occur at Junior High School 1 Asembagus. The researcher's data-gathering approaches include observation, interviews, and documentation. The researcher's data-gathering approaches include observation, interviews, and documentation. According to the findings of this study, teachers implement Islamic spiritual extracurricular activities and school environmental support in the form of spiritual activities in the school environment, and students participate in daily, weekly, and annual activities, encouraging students to be more obedient in worship, carry out religious commands, and avoid His prohibitions. Enhancing their piety, faith, and tolerance and teaching them decent manners. This practice not only makes youngsters more religious, but it also helps them behave better in ordinary situations.
Barreras y factores de calidad en atención a pacientes gineco-obstetra
Authors: Jerez-Masaquiza Fanny Violeta , Erika Valeria Chunata-Chacha Erika Valeria Chunata-Chacha , Donoso-Noroña Riber Fabián
Published: January 2025

Objetivo: Analizar las barreras y factores de calidad en atención a pacientes gineco-obstetra. Método: Descriptiva observacional. Resultados: el 75% indicaron que recomendarían a embarazadas que acudan a la atención en el Hospital IESS Ambato, el 20% no sabe si recomendaría o no y el 5% no lo recomienda, debido a algunas pacientes manifestaron tener inconvenientes al momento de acceder por turno en la Institución. Conclusión: El análisis de barreras y factores de calidad en la atención a pacientes gineco-obstetra en el Hospital IESS-Ambato evidencia la importancia de una atención de calidad que incluya una comunicación efectiva, el acceso oportuno a los servicios, la información clara y completa, y el fomento de la lactancia materna.
Efecto de los diferentes irrigantes en la remoción del barro dentinario en dientes tratados endodónticamente
Authors: Armendáriz-Silva Alyson Danniela , Mera-Sánchez Emily Adriana , Arroyo-Lalama Emma Maricela
Published: January 2025

Objetivo: Analizar el efecto de los diferentes irrigantes en la remoción del barro dentinario en dientes tratados endodónticamente. Método: Descriptiva documental. Conclusión: La remoción efectiva del barro dentinario en dientes tratados endodónticamente es esencial para el éxito a largo plazo de la terapia endodóntica. La elección adecuada de irrigantes y técnicas de irrigación, considerando las propiedades químicas y biológicas de cada agente, así como la implementación de estrategias para mejorar la eficacia de la limpieza y desinfección del sistema de conductos radiculares, son fundamentales. La continua investigación y el desarrollo de nuevas formulaciones de irrigantes y técnicas de irrigación prometen mejorar aún más los resultados clínicos y la experiencia del paciente en el campo de la endodoncia.
Efectos de la radiación ionizante en la cavidad oral durante y después de su exposición
Authors: Acosta-Vargas Mónica Alexandra , Paredes-Pinto Nicole Estefanía , Pérez-Villacrés Jhoseline Melissa , Villagrán-Fiallos Luis Felipe
Published: January 2025

Objetivo: Analizar los efectos de la radiación ionizante en la cavidad oral durante y después de su exposición. Método: Descriptiva documental. Conclusión: La radioterapia en la cavidad oral presenta desafíos significativos que requieren una atención multidisciplinaria y estrategias preventivas y terapéuticas efectivas. La mucositis oral aguda, la xerostomía persistente y la osteorradionecrosis son solo algunas de las complicaciones que pueden surgir durante y después del tratamiento. Sin embargo, mediante la colaboración estrecha entre odontólogos y oncólogos, junto con la educación continua del paciente y la investigación innovadora, es posible mejorar los resultados clínicos y la calidad de vida de quienes enfrentan este desafío. La identificación de biomarcadores predictivos y el desarrollo de terapias personalizadas pueden allanar el camino hacia un manejo más efectivo de los efectos adversos de la radioterapia en la cavidad oral, proporcionando así un cuidado integral y centrado en el paciente.
Eficacia de la irrigación ultrasónica y la irrigación activada por láser en endodoncia
Authors: Fierro-Ortiz Katherine Estefanía , Valle-Baldeón Luis Antonio , López-Torres Rómulo Guillermo
Published: January 2025

Objetivo: Analizar la eficacia de la irrigación ultrasónica y la irrigación activada por láser en la eliminación de bacterias y residuos dentinarios durante el tratamiento de conducto radicular.  Método: Descriptiva documental. Conclusión: Se confirmo que tanto el láser Er:YAG y el ultrasonido RinsEndo, son efectivos en la desinfección de los conductos radiculares, sin incrementar la concentración de la solución irrigante y confirmando un efecto de desinfección mejorado notablemente, a menor movimiento de la solución en ambas regiones del conducto. Haciendo que de esta forma aumente la seguridad del operador al realizar la irrigación dentro del conducto, evitando accidentes y del paciente al no presentar complicaciones o dolor postoperatorio.
Eficacia de la profilaxis antibiótica en pacientes con riesgo de endocarditis infecciosa
Authors: Tobar-Peñaherrera Adriana Nicole , Moya-Salazar Myriam Ernestina , Salazar-Duran María de los Ángeles , Villagrán-Fiallos Luis Felipe
Published: January 2025

Objetivo: Analizar la eficacia de la aplicación de la profilaxis antibiótica en los pacientes que presentan endocarditis bacteriana. Método: Descriptivo documental. Conclusión: La eficacia de la profilaxis antibiótica en pacientes con riesgo de presentar endocarditis bacteriana es alta en pacientes que tienen mayor prevalencia de desarrollarla, sin embargo, antes de administrar se debe evaluar correctamente al paciente y determinar si es adecuada para el procedimiento odontológico a realizar, además esta debe estar acompañada de educación y prevención en el paciente. En el presente estudio se evidencia que la eficacia es del 98,95%, en pacientes en los que se administró la profilaxis y cuidados de correcta manera.
Fluorosis dental y su relación con las vertientes de agua
Authors: Toalombo-Curichumbi Daisy Lisbeth , Nuñez-Zambrano Paola Monseratte , Benites Rolando Manuel
Published: January 2025

Objetivo: Determinar la relación del origen de la fluorosis dental y el consumo de agua proveniente de vertientes naturales. Método: Descriptivo documental, la población fue de 15 articulos publicados en Scielo, Latindex, PubMed. Conclusión: Se debe seguir realización regulación sobre las concentraciones de flúor en agua, debido a que aún existen sectores de la región andina en donde la concentración de fluoruro en agua sigue siendo algo al no ser tratado. El agua de consumo que proviene de vertientes naturales o potables no regularizadas debe ser hervida.
Frenillos bucales, origen, diagnóstico, pronóstico y tratamiento
Authors: Vásquez-Barberán Samantha de los Ángeles , Ambulidí-Barahona Heidy Marisol , Palacios-Chiriboga Gilda Isabel , Vaca-Altamirano Gabriela Liseth
Published: January 2025

Objetivo: Analizar los frenillos bucales, origen, diagnóstico, pronóstico y tratamiento. Método: Descriptivo documental, la población fue de 15 articulos publicados en Scielo, Latindex, PubMed. Conclusión: La prevalencia de los frenillos bucales en Ecuador manifiesta que los frenillos labiales superiores son los más comunes en el género masculino, mientras que en el género femenino prevalece la anquiloglosia que es el frenillo lingual anómalo.
Hiperplasia fibrosa
Authors: Parra-Cabay Katherine Stephanie , Logroño-Chávez Víctor Santiago , Pazmiño-Alban Genesis Constanza , López-Nacimba Brian Steven
Published: January 2025

Objetivo: Presentación de un reporte de caso sobre Tratamiento Quirúrgico de Hiperplasia (Caso Práctico). Método: reporte de caso. Resultados: Paciente de 53 años asiste al Consultorio Odontológico de “Uniandes”, manifiesta que ella utiliza una prótesis total, sin embargo hace un tiempo atrás empezó a sentir incomodidad y dolor al momento de usarla, posterior examinan a la paciente y luego la refieren al área de prótesis debido a que dicha paciente es edéntula y usa prótesis, en la mencionada área le explican que para realizarse una prótesis ella requiere como primer paso realizarse una intervención quirúrgica. Conclusión: La hiperplasia fibrosa es una patología que comúnmente se da en la cavidad bucal, misma que se caracteriza por ser una lesión hiperplásica inflamatoria reactiva en razón de un trauma crónico.
Injertos óseos usados en cierre de fisura palatina
Authors: Villegas-Fonseca Alonso Javier , Núñez-Hernández Mishell Stephany , Sanchez-Sanchez Javier Estuardo
Published: January 2025

Objetivo: Identificar los injertos óseos más utilizados en el cierre de fisuras palatinas mediante una revisión de la literatura científica. Método: Descriptivo documental, se analizaron 15 articulos publicados en PubMed, Scielo, Latindex 2.0. Resultados y conclusión: Las áreas donantes preferidas para el tratamiento de fisuras alveolopalatinas son la calota, la cresta iliaca y la tibia, ya que proporcionan células inmunocompetentes y generan cantidades significativas de hueso esponjoso. Se ha determinado que, en pacientes con dentición mixta, el uso de injertos óseos alveolares secundarios proporciona grandes beneficios en el tratamiento del cierre de fisuras alveolopalatinas.
EVALUATION THE EFFECTIVENESS OF PRODUCT INNOVATIONS IN MODERN CONDITIONS
Authors:   Rostov branch of the Russian state university of justice, Marakhovskaya Inna Yuryevna
Published: January 2025

Subject. Currently, the implementation of various types of innovation is becoming an urgent task for each individual organization, each region, and the country as a whole. A special place in the management of innovations is occupied by the assessment of their effectiveness. Therefore, the theoretical part of this article is devoted to the issue related to the analysis of existing methods for assessing innovations, identifying their advantages and disadvantages. And the practical part, finding new methods for assessing product innovations. Objective. The main objective of the work is to identify practical ways to improve the effectiveness of product innovations. Methodology. General scientific and specific research methods are used: structural-functional and comparative analysis, synthesis, generalization, systematization. Results. The conducted research has established that most methods used in assessing the effectiveness of product innovations weakly motivate the manufacturer to achieve the result. Since the existing assessment methods do not include indicators of the connection between the consumer's costs of purchasing the product of innovation and the effect on the consumer. Which in today's conditions has a key importance in making a decision of a potential buyer to purchase a product. The indicators that assess innovations from the consumer's side include indicators of business and operational returns. Scope of application of results. Assessment of innovations. Conclusions. Effective innovation management is becoming increasingly important for organizations, since without it it is impossible to ensure competitiveness in modern conditions. One of the elements of innovation management is their evaluation. Research has shown that it is advisable to supplement methodological approaches to assessing efficiency with indicators for assessing operational and business returns by V.B. Bratolyubov, which reflect the relationship between costs and the result for the consumer. Determining these indicators will allow manufacturers to make more effective decisions in innovation management.
DIGITAL BUSINESS TRANSFORMATION: TOOLS, STAGES OF IMPLEMENTATION AND ECONOMIC ASSESSMENT OF INVESTMENT EFFECTIVENESS
Authors:   Kazan state university of architecture and civil engineering, Zagidullina Gulsina Mansurovna , Bikmuratov Talgat Malikovich ,   Kazan state university of architecture and civil engineering, Kadimov Damir Rustamovich ,   Kazan state university of architecture and civil engineering
Published: January 2025

The economic changes taking place in recent years, related to the formation of the digital economy, entail the development of digital technologies and the transition to digital transformation in various sectors of the economy. In this regard, despite the significant number of scientific papers on digital transformation, its further scientific and methodological elaboration is required. The article analyzes digital technologies as the basis of digital transformation, identifies the specifics of industry affiliation, suggests a new basic model of the stages of implementation of digital transformation and a method for economic assessment of the commercial effectiveness of investments in it. It is shown that digital transformation should not be considered as an independent process, but as part of corporate business processes and strategy, and it should also have measurable goals. The study addresses the issue of building a comprehensive system of digital transformation of enterprises, taking into account current trends. The relationship between the purpose, tools, model and assessment of digital transformation is demonstrated, as well as the difficulties of business entities in the transition to the digital path of development. An expanded definition of digital transformation is proposed, indicating the potential benefits and advantages of its implementation. The provisions of the research are based on modern scientific articles, dissertations and an analysis of the practical activities of companies. Due to the fact that digital transformation requires significant investments, the results of this study will be of interest to enterprises as part of building their own assessment systems. At the same time, the authors' proposed model of the stages of digital transformation implementation will make it possible to outline guidelines for the restructuring of internal processes and the transition to a new business model.
Information and analytical systems in corporate management support
Authors: Bradul Olexandr , Antonov Serhii
Published: January 2025

Introduction. Significant technological shifts in production, the introduction of new forms of entrepreneurship based on private ownership and share capital, socio-economic changes in society, the progress of science, and the application of its achievements in practical activities form the prerequisites for further development and effective functioning of Ukraine's economy.
Today, there are problematic issues in the economic analysis of corporate activities, necessitating the justification for the need to change their paradigm. This requires the division of methodologies for assessing the efficiency of business units within the corporate structure. The research focuses on forming an information-analytical system for supporting corporate management, summarizing the methodology for analyzing economic indicators for operational and strategic management.
Aim of the article. The purpose of the article is to study the achievements of global and Ukrainian economic science and to utilize the experience of both foreign and national practices to develop key provisions of the theory, methodology, and organization of accounting and analytical support for the management of corporations operating within Ukraine's economy.
Method (methodology). The research applied historical and systemic approaches to the establishment and transformation of corporations' analytical systems; methods of induction, deduction, scientific abstraction, and graph theory in the construction of dynamic models for analysis; and modeling methods for designing a computerized information system for accounting and analysis.
Results. The theoretical justification of a new approach to solving the problem is presented, which addresses the inconsistency between the current state of methodology and organization in corporate activity analysis and the requirements for effective management and the growing role of corporate structures in Ukraine's economic development. A procedural structure for a computerized information system to analyze corporate activities has been developed, enabling the integrity of the analysis system despite the fragmentation of information sources, analysis tools, and performers, thereby creating adequate analytical support for corporate management in real-time.
Systematic approach to the functional features of the formation of HR marketing in the emerging economy
Authors: Reshmidilova Svitlana , Aleynyk Pavlo , Bondarenko Denys
Published: January 2025

Introduction. In the conditions of the development of processes of globalization, digitalization, strengthening of market competition, success can be achieved by enterprises that are constantly looking for new ways to adapt to the constantly changing market conditions of their operation. Combining HR management with marketing is a necessary condition for attracting and retaining the best employees for successful business. HR specialists will be able to work effectively in the labor market only if they use the achievements of marketing.
The application of the marketing approach in the activities of the enterprise with personnel management will allow to increase the productivity of production without involving additional resources. In this regard, there is a need to develop the conceptual foundations of HR marketing, mastering marketing technologies in this field and the necessary tools for marketing activities. This requires non-standard approaches to the formation of HR marketing.
These issues are especially relevant during the period of development of the emerging economy, one of the important components of which are the processes of social development. These processes are dynamic, mobile and change under the influence of information technologies. In such conditions, the processes of forming HR marketing at enterprises must be ensured taking into account the requirements and principles of the emerging economy.
Purpose of the article is to research of the main trends of HR marketing caused by the development of the emerging economy; clarifying the conceptual basis of HR marketing; systematization of the stages of systematic formation of HR marketing at the enterprise.
Method (methodology). The information method was used for the research in order to obtain informative data from scientific sources and the Internet; classification and comparative analysis (identifying the functional features of HR marketing), a systematic approach (characterizing the stages of forming the company’s HR marketing system); generalization method (formulating research conclusions).
Results. The influence of the information sphere on the development of HR marketing processes and the need to form HR marketing in accordance with the requirements of the emerging economy are substantiated. The place of HR marketing in the enterprise management system is determined. The conceptual content and provisions of HR marketing have been clarified. The application of elements of emergency management in the modern practice of marketing management is argued. The application of a systematic approach to the formation of HR marketing at the enterprise is substantiated. The stages of formation of HR-marketing are established with their detailing. The advantages of the systematic application of tools for the formation of HR-marketing are highlighted.
The role of agricultural extension workers in digital transformation at the Agricultural Extension Center in Lowokwaru Malang
Authors: Salsabella Irene Hanies , Bakhtiar Ary , Ibrahim Jabal Tarik
Published: January 2025

Introduction: The pivotal role of the agricultural sector in Indonesia's economic advancement stems from the employment of a significant portion of the Indonesian populace. Central to this sector are agricultural extension workers tasked with fostering motivational shifts, altering operational methodologies, and instilling adaptive practices congruent with technological advancements. This research endeavors to scrutinize the modus operandi of agricultural extension workers amidst the digital metamorphosis era within the Agricultural Extension Center situated in Lowokwaru, Malang, Indonesia. Methods: Employing a Mixed methods approach, this study draws upon primary and secondary data sources. Thirty samples, affiliated with the Farmers Group at the Agricultural Extension Center in Lowokwaru Malang, constitute the study cohort, selected through purposive sampling techniques. Data accrual involves questionnaire administration, employing the Likert scale as the measurement metric. Statistical analysis entails multiple linear regression, facilitated through SPSS 22 software. Results: Simultaneously, variables embodying extension workers' roles as facilitators, innovators, motivators, dynamists, and educators collectively impact the income of registered farmers at the Agricultural Extension Center in Lowokwaru, Malang. Conclusion: This study reveals that the roles of extension workers as facilitators, innovators, and educators significantly enhance farmers' capacity to integrate digital technology into their agricultural practices. Nevertheless, the absence of direct statistical significance in some roles suggests the interplay of other critical factors, such as farmers' readiness to adopt technology and external support mechanisms. These findings highlight the need for targeted interventions to bolster extension workers' capabilities and farmer engagement with digital innovations.
Indigenous microorganisms from the corm of banana improve the growth and yield of three varieties of cucumber (Cucumis sativus L.)
Authors: Lasmini Sri Anjar , Burhanuddin  , Taiyeb Asgar , Surya I Komang
Published: January 2025

Introduction: Cucumber (Cucumis sativus L.) is a type of vegetable that is widely consumed by the public. Cucumber production is still low due to cultivation systems that are not by standard operating procedures and low soil fertility. Therefore it is necessary to improve cultivation techniques through the use of quality seeds and fertilization. The study aimed to determine the effect of various concentrations of indigenous microorganisms from the corm of banana on the growth and yield of three varieties of cucumber. Methods: The study used a randomized block design with two factors: cucumber variety (Hercules, Mercy, Harmony) and concentration of indigenous microorganisms from banana corm (0, 200, 400, 600 ml/L). Each treatment was repeated three times with eight plants per plot, totaling 288 plants. Results: There was an interaction between cucumber varieties and microorganism concentrations. The Harmony variety with 600 ml/L of microorganisms showed the best results: plant height (162.03 cm), number of leaves (31.92), branches (3.57), fruits (10.58), and fruit weight (156.28 g). Conclusion: The Harmony variety and 600 ml/L concentration of indigenous microorganisms from banana corms significantly improved cucumber growth and yield. This method can reduce production costs by using easily available and cheap materials, decreasing reliance on expensive synthetic fertilizers.
Agudeza visual en estudiantes universitarios de la Universidad Nacional del Nordeste
Authors: Martina Vignolo  , Joaquina Cibils Jacobo  , Rosana Gerometta  , Miguel Eduardo Cibils
Published: January 2025

Introduction: Visual acuity or central vision is the ability of the eye to differentiate two points close to each other and separated by a certain angle. According to the World Health Organization (WHO), people considered visually impaired are all those who have a visual acuity value of less than 0.3 (3/10 or 6/18). Objective: To evaluate the visual acuity of a random group of university students. Methodology: Observational, descriptive, and cross-sectional study on the student population of the Universidad Nacional del Nordeste. The sample was random through spontaneous consultation, where a total of 152 students were included. Visual acuity (VA) was evaluated using Snellen test charts, the optotypes were placed in the horizontal plane of the student’s vision, at a distance of six meters (optical infinity). Results: A 36% of the people evaluated had normal visual acuity, 63.8% had visual acuity impairment in one or both eyes, of which 15.7% had visual acuity of 8 to 10 tenths, 19.1% of participants had visual acuity of 7 to 4 tenths and 14.47% of students had visual acuity of 3 to 1 tenth. Finally, a group of 21 people (13.8%) was detected with visual acuity of notable difference in both eyes. Conclusion: It was evident that there is a high percentage of university students who have altered visual acuity, which is why ophthalmological check-ups are recommended in universities in order to detect and prevent prevalent pathologies in time Because of what has been developed, it is suggested to continue studying visual acuity in university students.
EVALUATION OF VAGINOSCOPY VERSUS TRADITIONAL APPROACH TO HYSTEROSCOPY IN AUB PATIENTS IN A TERTIARY CARE CENTRE: A RETROSPECTIVE OBSERVATIONAL STUDY
Authors: Chaurasia Amrita , Ojha Vandana , Dubey Mona , Pandey Seema , Kesarwani Muskan
Published: January 2025

Introduction: Hysteroscopy allows direct visualization of the uterine cavity [1]. Hysteroscopy is the preferred technique
for the assessment of various conditions like abnormal uterine bleeding (AUB), postmenopausal bleeding, intracavitary
lesions lesions , removal of foreign bodies, mullerian anomaly, infertility Worldwide, the number of and for managing intrauterine pathology [2].
diagnostic hysteroscopies are rapidly rising along with change in trend of entry approach to hystero [3,4] scopy. This study was done to evaluate
the techniques of hysteroscopic entry and highlight the advantages and need towards the advanced approach to hysteroscopy among patients and
healthcare providers. Aims & Objectives: To evaluate the various determinants and outcomes of vaginoscopy and traditional approach to
hysteroscopy. The Retrospective Observational study was conducted in SRN hospital, Department of Ob Material & Methods: stetrics and
Gynaecology, MLN Medical College, Prayagraj, India for a period of 1 year. Study was started after ethical clearance from IEC. A total of 240
subjects who underwent hysteroscopy for assessment of AUB during specified period were recruited for the study, fulfilling the inclusion and
exclusion criteria, using random sampling technique. The data were collected and analysed retrospectively. Out of total 240 cases of Results:
AUB, 97% underwent successful diagnostic/ operative hysteroscopy via both vaginoscopy and traditional technique. The time required for the
completion of procedure depends upon the indication and type of hysteroscopy performed not on the approach to entry to the uterus.There was
almost no difference in the surgical outcome between vaginoscopy and traditional hysteroscopy. Conclusion: Vaginoscopy requires a shorter
time for the completion of the diagnostic procedure and involved lesser pain in less number of patients than the traditional hysteroscopy. The
success rates are comparable between the two techniques. Traditional hysteroscopic method should be reserved for challenging cases or for
certain pathologies. Consequently, we advise using vaginoscopic approach as the preferred method for diagnostic hysteroscopies.
POSTOPERATIVE OUTCOMES OF COLLAGEN SHEET VERSUS BUCCAL FAT PAD IN THE RESURFACE OF THE RAW AREA FOLLOWING THE EXCISION OF FIBROUS BANDS IN OSMF- PROSPECTIVE CLINICAL STUDY.
Authors: Jadhav Pranavi , Naik Sanjeev , Sinha Ramen , Tiwari Prabhat , Kumar Salavadi Revanth
Published: January 2025

This study was designed to compare the use of collagen sheet, on one side and BFP on the contra lateral side to resurface
the raw area following the excision of fibrous bands. This prospective study comprised 46 patients reporting to the
department of Oral and Maxillofacial Surgery, SSCDS, Hyderabad with a chief complaint of reduced mouth opening. Patients were examined
postoperatively on the first day, first week, second week, third week, fourth week, eighth week, three months, and six months. Pain, interincisal
opening, edema, and graft epithelialization were examined postoperatively. The findings were analyzed with SPSS software version 21.
Intraoperatively, the average time for BFP was 20.91 minutes and 15.91 minutes for collagen sheet. VAS values for pain differed significantly
between groups. On the first postoperative day, pain was moderate to severe at the BFP site and mild to moderate at the collagen sheet site; these
differences were statistically significant (p=0.002). On the 7th day, the VAS scores for both sites had decreased, but the disparities remained
statistically significant, resulting in a mean VAS score of 2.00 and 1.00 on BFP and collagen sheet sites, respectively (p- 0.001). Both methods
resulted in almost normal mouth opening with no significant difference in relapse proportion, in terms of postoperative healing and surgical
convenience. The use of a collagen sheet is better than BFP transposition. Collagen sheet had an ed Summary: ge over BFP intraoperated
adaptation time and post operative pain.
DIGITAL STRAIN AND OCULAR HEALTH: INVESTIGATING THE LINK BETWEEN DRY EYE DISEASE AND PROLONGED SCREEN TIME
Authors: A. Ganja Arzoo , Singh Salaria Nitin
Published: January 2025

In the digital age, prolonged screen time has become an integral part of daily life, leading to a rise in digital eye strain and
associated ocular health issues. Among these, Dry Eye Disease (DED) has emerged as a significant concern, characterized
by symptoms such as discomfort, visual disturbance, and tear film instability. This study explores the link between extended screen exposure and
the prevalence of DED, focusing on mechanisms such as reduced blink rate and increased tear evaporation. Data from clinical assessments and
participant surveys reveal a strong correlation between screen habits and the severity of DED symptoms. Preventive strategies, including
behavioral adjustments, ergonomic interventions, and the use of ocular lubricants, are recommended to mitigate risks. The findings underscore the
urgent need for awareness and proactive measures to protect ocular health in the context of increasing digital dependency.
INNOVATIVE APPROACH IN POST-ENDODONTIC RESTORATION: PRESERVING TOOTH STRUCTURE AND FUNCTION: A CASE REPORT.
Authors: Premarajan Pranav , A Srirekha , Mathew Maria , Satyakamal V , Kumar D G Ajay
Published: January 2025

Root canal treated tooth often necessitates placement of crown to ensure long term success and functionality of tooth from
external forces such as biting and chewing. Conventional crown, although used commonly as a post endodontic
restoration, has certain setbacks. Full coverage crowns requires extensive removal of tooth structure which may compromise structural integrity of
tooth ultimately leading to failure. The concept of minimal preparation and conservation has led to various innovative designs to preserve dentin
and maintain the integrity of tooth. In this case report, crown was designed taking into consideration peri cervical dentin, forces acting on
functional and non functional cusp and Deeman's criteria of crown preparation
A STUDY TO ESTIMATE THE PREVALENCE OF THROMBOCYTOPENIA IN NEONATES ADMITTED IN NICU AND EVALUATE THE EFFECT OF PLATELET TRANSFUSION ON NEONATAL OUTCOMES
Authors: Chauhan Ashish , Kumar Goel Yogesh , Navaney Hiru
Published: January 2025

Introduction:Thrombocytopenia, defined as a platelet count of less than 150 × 10^9/L, is common among neonates, swith an occurrence rate of up
to 30%. Neonates often receive platelet transfusions, many of which may be unnecessary. This study aimed to evaluate the prevalence of
thrombocytopenia, its causes, and the effect of platelet transfusions on neonatal outcomes in NICU admissions at Saraswathi Institute of Medical
Sciences, Hapur, UP.
Objectives:
1. To estimate the prevalence of thrombocytopenia in neonates admitted to NICU.
2. To assess the common causes of neonatal thrombocytopenia.
3. To evaluate neonatal outcomes in thrombocytopenic patients following platelet transfusion.
Methods: This cross-sectional study was conducted from August 2022 to July 2024 at the Saraswathi Institute of Medical Sciences. Atotal of 500
neonates admitted to the NICU were included. Neonates with various conditions were excluded based on predefined criteria. Data on maternal
history, neonatal demographics, and clinical characteristics were collected. Platelet counts were measured on the first, third, and fifth day of life.
Statistical analyses were performed to determine the associations between clinical variables and thrombocytopenia severity. Result: Out of 500
neonates, 126 (25.3%) had thrombocytopenia. Of these, 99 cases (19.8%) were early-onset and 27 cases (5.4%) were late-onset.
Thrombocytopenia was more common in preterm, low birth weight (LBW), and small for gestational age (SGA) neonates. Significant associations
were found between thrombocytopenia and maternal conditions such as pregnancy-induced hypertension (PIH), as well as neonatal conditions like
sepsis, gastrointestinal bleeding, and intraventricular hemorrhage (IVH). Among neonates with thrombocytopenia, those receiving platelet
transfusions had higher severity of the condition. The mortality rate among thrombocytopenic neonates was 6.3%, with severe thrombocytopenia
being a significant factor. Conclusion: Thrombocytopenia in neonates is prevalent in NICUs and is significantly associated with prematurity,
LBW, SGAstatus, and maternal PIH. The severity of thrombocytopenia impacts neonatal outcomes, with severe cases leading to higher mortality.
Effective guidelines and protocols for platelet transfusion are essential to improve neonatal care and minimize unnecessary donor exposure.
APPLICATION OF YOKOHAMA SYSTEM FOR REPORTING BREAST FINE NEEDLE ASPIRATION CYTOLOGY IN CORRELATION WITH HISTOPATHOLOGICAL AND RADIOLOGICAL FINDINGS
Authors: Chandrakant Patel Priyank , Bagga Permeet Kaur , Ohri Poonam , Kaur Ramandeep , Kumar Kohli Sanjeev
Published: January 2025

Breast cancer is the leading cause of cancer-related mortality among women, with a significant incidence in India. Fine Needle Aspiration Cytology
(FNAC) is effective for diagnosing benign and malignant breast lesions but its use varies across regions. The Yokohama System, established in
2016, categorizes FNAC findings into five groups, providing standardized diagnostic guidance. This study aimed to categorize FNAC cases using
the Yokohama System, correlate results with histopathology and radiology, and calculate the risk of malignancy (ROM) for each category. Among
300 cases, FNAC categories included insufficient material (4.3%), benign (43.3%), atypical (12.67%), suspicious (3.6%), and malignant (36%).
The sensitivity, specificity, PPV, NPV, and diagnostic accuracy of FNAC were 100%, 97.6%, 98.4%, 100%, and 99%, respectively. ROM was 0%
for categories 1 and 2, 18.18% for category 3, 87.5% for category 4, and 100% for category 5. The Yokohama System enhances diagnostic
precision.
RESISTIVE INDEX OF ANTERIOR CEREBRALARTERY IN LATE ONSET NEONATAL SEPSIS
Authors: Tejus S Kunal , Murthy DV Venkatesh , R Prema , E Adarsh
Published: January 2025

Background And Objectives: Point of care neonatal ultrasound is a valuable tool for evaluating the heart, brain, lungs, and abdomen in cases of
neonatal sepsis. Understanding blood flow in the brain during neonatal sepsis is complex and not well understood. This study aimed to measure
blood flow in the brain by checking the resistive index (RI) of the anterior cerebral artery in babies with late-onset neonatal sepsis (LONS).
Methods: All newborns admitted to our neonatal intensive care unit from January 2023 to June 2024 with suspected late-onset neonatal sepsis
(LONS) had a bedside trans-cranial Doppler ultrasound to measure the resistive index (RI) of the anterior cerebral artery within 24 hours of
showing symptoms. Babies with congenital heart disease, birth asphyxia, major birth defects, and genetic syndromes were excluded. Only those
with a positive culture were included in the final analysis. Results: Out of suspected late-onset neonatal sepsis (LONS) cases, 23 had positive
cultures and were analyzed. The mean admission weight was 2.04 kg, and the mean gestational age was 33+2 weeks. The most common bacteria
found was Klebsiella pneumoniae & Escherichia coli. The resistive index (RI) was high in 52.2% (12 out of 23), normal in 39.1% (9 out of 23) and
low in 8.7% (2 out of 23) of the cases. Conclusions: Late-onset neonatal sepsis (LONS) is a complex condition, and our study found it is linked with
a high resistive index (RI) majority of cases, suggesting reduced brain blood flow.
A Systematic Review and Meta-analysis of Randomized Controlled Trials on Comparing Transabdominal Preperitoneal Versus Lichtenstein Operations for Primary Inguinal Hernia Repair
Authors: Javed Muhammad Aslam , Abbas Muhammad Arshad , Murtaza Mudassar , Chaudhry Wasif Majeed , Faisal Adnan , Gillani Muhammad Mohsin
Published: January 2025

Background: Inguinal hernia repair is a common surgical operation being performed worldwide, and the primary objective of hernia repair is to reduce recurrence, minimize complications, and robust recovery. This systematic review and meta-analysis reviewed and compared two widely used surgical techniques: the Trans-abdominal Pre-peritoneal (TAPP) repair, a minimally invasive laparoscopic surgical technique, and the Lichtenstein operation, which is an open repair.
Methods: A thorough search was conducted across several databases, including PubMed, Cochrane Library, Google Scholar, and Web of Science, from 2004 to August 2024. We searched a combination of keywords and medical subject-related headings related to "trans abdominal Pre-peritoneal," "TAPP Surgical Technique," "Lichtenstein open repair operation," "primary inguinal hernia," and "randomized controlled trials (RCTs)."
Studies included in the meta-analysis were grouped based on the primary outcomes of interest to elaborate a comprehensive analysis. In addition to the surgical operation and hospital stay duration, acute post-operative pain, return to work time, hematoma, wound infection, and seroma incidence were also measured. The Randomized controlled trials (RCTs) comparing TAPP and Lichtenstein operations for primary inguinal hernia repair and studies reporting on at least one of the above-mentioned outcomes were included. The studies with patients having incarcerated hernia, femoral or bilateral hernias were excluded. The risk of bias for included studies was assessed using the Cochrane Risk of Bias tool and sed on odds ratios (ORs), standardized mean differences (SMDs) and confidence intervals (CIs), a quantitative meta-analysis study was conducted.
Results: Nine Randomized Controlled Trials (RCTs) comparing the TAPP and Lichtenstein technique for primary inguinal hernia repair were included in the meta-analysis. The duration of the surgical procedure was longer in the TAPP group (46.3 to 96.12 minutes), compared to the Lichtenstein group (27.8 to 54.2 min). In terms of acute post-operative pain, the TAPP group reported lower pain scores (mean: 5.66) compared to the Lichtenstein group (mean: 8.53). The overall complication rate was lower for the TAPP group (Odds Ratio = 0.461) as compared to Lichtenstein repair.
Conclusion: The meta-analysis concluded that TAPP tops out with benefits like less post-operative pain and a robust recovery period. However, the Lichtenstein technique remains a widely used option, especially in settings where access to advanced Laparoscopic facilities and expertise might not be available.