bluuebunny/crossref_metadata_2025 huggingface dataset:
Formulation, Optimization and Evaluation of Ticagrelor Liquisolid Tablets for Enhanced Solubility
Authors: Shastri Utkarsh , P. Sutar Kishori , A Jadhav Vishwanath , S. Shirkoli Nisha
Published: May 2024

Purpose The study aims to use liquisolid compacts technology as a novel carrier to enhance Ticagrelor's solubility and release profile. Method: Formulation of liquisolid tablets was developed using the Design of Experiment (DOE) approach where the drug Ticagrelor was dispersed in PEG-600 and incorporated into carrier material (Neusilin US2) in the mortar, the liquid drug was permitted to absorb in the second stage. Aerosil-200 was used as a coating material, and Magnesium stearate and Sodium starch Glycolate were used as Lubricant and Disintegrating Agent respectively. The formulations were optimized and the carrier-to-coating ratio and mixing Aerosil-200 with Neusilin US2 effect on drug release from the formulation was investigated. The prepared liquisolid compacts were subjected to micrometric characterization, post-compression parameters, Fourier Transform Infrared Spectroscopy (FTIR), and Differential Scanning Calorimetry (DSC). Result: The cumulative drug release of all formulations in dissolution media varies from 82% to 96% and Formulation F9 showed a maximum cumulative drug release of about 96%. The drug contents of all formulations ranged from 91.06% to 99.01%. Disintegration time for all 1-9 formulations, clearly, all compositions disintegrate in less than 10 minutes. The cumulative drug release of all formulations varies from 82% to 96% Formulation F9 showed a maximum cumulative drug release of about 96% and the conventional tablet showed a cumulative drug release of about 80 %. The optimized liquisolid formulation F8 outperformed the other batches in terms of flow and compressibility across all formulations. Conclusion: Therefore, as per the results, it can be inferred that Ticagrelor, when formulated by a liquisolid approach, produce ameliorated dissolution and stability profile.
Antioxidant and Anti-inflammatory activity of the Terpenoidal fraction of Ethanolic extract of Byttneria herbacea
Authors: K. Kar Sanjeeb , K. Dixit Prasanna , S. Mishra Uma , Chowdhury M. Hossain
Published: May 2024

The goal of this study was to identify the bioactive principle of the plant Byttneria herbacea (Malvaceae) which has a wide range of traditional therapeutic uses.Column chromatography was used to separate the ethanolic extract of aerial parts of the plant with mobile phase Chloroform: Methanol (5:5). The fraction with Rf 0.62 on TLC with mobile phase Toluene:Ethyl acetate (85:15) imparting bluish color under UV 254 nm was giving the test of Terpenoids. The same fraction was assessed for Antioxidant and Anti-inflammatory activity.Antioxidant activity was performed by measuring the decolourizing activity followed by capturing the unpaired electron from the free radical 2,2-diphenyl-1-picrylhydrazyl (DPPH) and compared it with the standard anti-oxidant Gallic acid. To test anti-inflammatory activity in an experimental model of acute inflammation, the carrageenan-induced in rat paw edema method was employed.The antioxidant and the anti-inflammatory activities of the Terpenoid fraction were found to be satisfactory.
Ayurvedic Management of Refractory Atopic Dermatitis - Case Report
Authors: Bhatia Shreya , H. Yeola Gunvant , Sarjerao Shirkande Abhijeet , Kodre Shweta , Pansare Snehal , Zarin Khan Aqsa , Niware Mohini
Published: May 2024

The term 'eczema' refers to inflammation of the skin and makes the skin irritated. Most common type is atopic dermatitis or atopic eczema. Vicharchika (skin disease with excessive exudation) in ayurveda can be compared to atopic dermatitis (AD). It manifests as erythema, vesiculation and oozing in the acute stage, scaling, and crusting in the subacute stage and lichenification (hyperpigmentation, accentuation of skin markings and thickening of the skin) in the chronic stage. The current condition known as atopic dermatitis leads to eager, aroused skin. Most often, it takes the form of patches on the face, neck, trunk, or extremities. This article presents a case study of a child who is having signs and symptoms of vicharchika. According to ayurvedic etiopathogenesis (samprapti) patient was diagnosed with vicharchika and is treated accordingly by internal and external therapies. Assessment was conducted using subjective as well as objective criteria. Oral ayurvedic medications along with udvartanachurna for local applications as part of the treatment was given. This case was successfully treated using the chikitsasiddhanta of vicharchika. After treatment, there was noticeable improvement in both signs and symptoms. The course of treatment revealed no complications. The study's goals and objectives were to assess the efficacy of simple ayurvedic formulations for the treatment. This single case report highlights thatthis ayurvedic intervention generated beneficial results and raised the quality of life of the patient.
Methacrylic Acid Co-Polymers: Crucial agents for the Colon Targeted Oral Drug Delivery System
Authors: Patel Jaymin , Patel Kaushika , Shah Shreeraj
Published: May 2024

The objective of this research was to formulate an Ornidazole tablet capable of delivering the drug intact to the colon for the treatment of IBD, ulcerative colitis, and Crohn's disease. In the current investigation, pH-independent and pH-dependent polymers were used to target the Ornidazole tablet to the colon. This study evaluated two time-dependent (sustained release) polymers (Eudragit RS and Eudragit RL) and one pH-dependent polymer (Eudragit S100). The influence of the two formulation variables of the colon drug delivery system on the two response variables were examined simultaneously using a statistical 32-Full factorial design. X1 Ratio of Eudragit RS 100 to Eudragit RL 100 and X2 % weight gain with Eudragit S 100 were treated as independent variables in a factorial design, while Y5 and Y12 were treated as dependent variables. Through this procedure, a total of nine F9 samples were produced. Y5 in-vitro release should not exceed 10%, whereas Y12 should surpass 85%. Based on these results, batch B8 is considered the finest of all cohorts. According to the results, the enhanced formulation provides optimal intact drug delivery to the targeted region.
Physicians’ Perceptions regarding the Role of Vitamin D in COVID-19 Management: A Qualitative Study
Authors: Mosbah Katramiz Lin , Kamal Alkhlaidi Doaa , Ahsan Muneeb , Mostafa Hamed Dujana
Published: May 2024

Purpose: COVID-19 outbreak has created a public health crisis starting from December 2019. Vitamin D has raised as a protective factor that can take part in reducing risk of infection. It has an immunomodulatory wide spectrum action. This study aims to ascertain the physicians’ perceptions regarding Vitamin D role as adjuvant therapy in COVID-19 infection. Methods: A descriptive qualitative design was approached. Data collection took place in a governmental tertiary hospital in Dubai, United Arab Emirates. A semi-structured interview guide was developed and validated for this purpose. In-depth individual interviews with physicians (n=20) from different departments were conducted. The participants were enrolled until reaching the saturation level. The interviews were recorded and transcribed. A thematic content analysis was performed. Results: After analysis, three elemental themes with subthemes emerged that described physicians’ experience and perceptions: general protocol followed for prescribing Vitamin D in COVID-19 patients, Clinical effect of Vitamin D in COVID-19 disease, Vitamin D deficiency and COVID-19 mortality. Different responses were obtained from physicians reflecting their experience with COVID-19 patients. Conclusion: The findings revealed physicians’ experience of Vitamin D clinical effect in COVID-19. Physicians stated the different regimen of Vitamin D used in COVID-19 patients and declared the association of Vitamin D in different COVID-19 cases but, no relation of Vitamin D deficiency and COVID-19 mortality as per physicians’ experience.
Comparative Analysis of Weather Forecasting Using LSTM, BiLSTM, and CLSTM Networks
Authors: Nikunjkumar B. Nayak
Published: May 2024

Weather prediction plays vital role in the evaluation of various processes and phenomenon for the betterment of society. Weather forecasting depends on many parameters hence, it’s a multivariable prediction problem. Behavior of data involved in the prediction are in majority of time stochastics hence, conventional mathematical approaches are failed to predict accurate data. Classical computational methods fail in predicting chaotic data due to its limitation to have know-how about behavior of data. Artificial Intelligence and Data Processing techniques is appealing investigators due to its efficiency to predict data based on its learning capability, without any know-how about the behavior of data. In this paper, Artificial Intelligence based approach LSTM, BiLSTM, and CLSTM are used to predict time series weather data prediction. Data considered are Pressure, Humidity, Temperature, and Maximum wind speed as input data. Neural Network based approaches are used to predict Average wind speed based on above inputs. The performance of above Artificial based approaches is compared to predict time series Average wind speed. MATLAB is used as software tool to implement Artificial Intelligence approaches. It has been observed that CLSTM algorithm outperformed other two algorithms LSTM and BiLSTM algorithm.
Conservation Biogeography of Australasian Marsupials
Authors: Fisher Diana
Published: May 2024

The diverse and distinctive Australasian marsupial fauna has experienced considerable loss over the last 200 years. Seventeen of the 176 Australian marsupial species have become extinct in this period ( 10%), far higher than the global average (1.4%). Many extinct Australian marsupials were formerly abundant and widespread. About 40% of Australian marsupials are now threatened. The pattern of decline in Australian marsupials is broadly similar to that of Australia’s native rodents- invasive mammalian predators and land use that facilitates them are the major problems.

Knowledge of the marsupial faunas of Papua New Guinea and Indonesia is relatively poor. Both regions have high endemism. There are 96 species of marsupials on the main island of New Guinea and surrounding small islands, and 15 species in Wallacea (the islands of Indonesia and East Timor east of Wallace’s line) including five shared with New Guinea. Although none are listed as Extinct, two Critically Endangered marsupials are flagged “possibly extinct.” Most threatened New Guinean and Wallacean species follow the globally typical pattern of high vulnerability in island endemics and small-range mammals with specialist habitats. The major threats to marsupials of New Guinea and Indonesia are habitat loss, hunting, and low levels of awareness and investment in conservation and research. Many Australasian marsupial species – particularly mountain-top endemics are increasingly threatened by climate change.
"Action and reaction" - a new public sector effectiveness assessment methodology
Authors: Cap Vilem , Feurich Marek , Lukavec Martin
Published: May 2024

The main contribution of the paper is the development of a new way of assessing the efficiency of public administration using statistical methods - multivariate regression (identification of exogenous factors) and residual analysis (identification of regression residuals). The methodology presented is intuitive, practical and, if appropriately set up, globally applicable for the evaluation of a wide range of processes taking place in the public sector on the principle of "action and reaction". Putting the methodology into practice can go some way to satisfying the "taxpayer hunger" for information about whether the money they pay in taxes is being used wisely. It makes it possible to assess efficiency in a particular institution or to compare similar processes in several institutions over a given period of time. The methodology has been developed on the basis of audit findings (prepared by the supreme audit institution for the public sector in a democratic state) and their implications. The developed methodology brings a new perspective to the traditional claim that public sector effectiveness is virtually impossible to measure and that factors for objective evaluation of public sector managers cannot be easily established.
Fatty acids composition, lipids health indices and enzyme activities of longissimus thoracis muscle of six breeds of sheep produced on pasture in Northern region of Uruguay
Authors: Guerra Maria Helena , Cabrera Maria Cristina , Franco Juan , Bentancur Oscar , Saadoun Ali
Published: May 2024

The determination of fatty acids composition of glycerolipids and glycerophospholipids of meat from longissimus thoracis of six breeds of lamb produced on pasture in Uruguay was undertaken by gas chromatography. Also some lipids health indices and lipids metabolism enzymes were determined. The studied lambs were males aged of 11–12 months of breeds and biotypes Highlander® (H), Merino Dohne (MD), Corriedale (C), Corriedale Pro® (CPRO), a crossing between Corriedale × Australian Merino (C×AM) and Romney Marsh (RM). The animals were reared on pasture in identical conditions without supplementation. The grazing was rotational based on a winter annual crops oats (Avena sativa spp.), cocksfoot, (Dactylis glomerata spp.) and white clover (Trifolium repens spp.). The results of the study did not show substantial differences between breeds regarding the fatty acids composition of meat, except for few relevant fatty acids such as C16:0 (MD>C), C18:3n3 (H<C) and CLA (HCPRO, CxAM), C18:2n6 (H<CxAM) and C18:3n3 (H<C) for glycerophospholipids. Likewise, other differences were outlined such as the anteiso monomethyl fatty acid content (MD<RM), the hypocholesterolemic/hypercholesterolemic ratio (MD<C). For lipids metabolism enzymes indices, MD showed a lower Δ–9 desaturase enzyme for C16:0 than C, CPRO and CxAM. Also, H showed a lower Δ–6 desaturase enzyme activity than C, and both MD and CxAM showed a lower elongase enzyme activity than C. The results of the present investigation showed that the meat of the lamb of the different breeds overall present good lipids nutritional indicators, in comparison with the results of other research in lambs. That information could help lamb producers in Uruguay to promote their products based on scientific data.
Evaluation of the relationship between periodontal diseases and oxidative stress parameters in cats
Authors: Yurdakul İbrahim , Çatak Mehmet Akif
Published: May 2024

Periodontal disease, which is defined as inflammation of the tissues and supporting structures surrounding the teeth, can be observed in cats starting from the age of 2. Periodontal diseases start with Gingivitis, which is the early stage of periodontal disease. Gingivitis can arise from inflammation of the gums due to plaque, a white or yellowish biofilm of bacteria on the tooth surface, and the toxins produced by these bacteria. It can also result from inflammation of the periodontal tissues, including dental calculus or other periodontal tissues. A total of 242 cats were brought to the clinic for surgical diseases and 14 cats (5.78%) were found to have periodontal diseases. Although there have been several studies on oxidative stress, there are very few publications investigating the relationship between oxidative stress and periodontal diseases in cats. The aim of this study is to measure serum MDA, IMA and GSH concentrations and SOD and CAT activities in cats with periodontal diseases and to evaluate the relationship between oxidant and antioxidant status, which are indicators of oxidative stress. In the study, blood samples taken from cats with periodontal disease were centrifuged and serum was removed. MDA and IMA levels of cats with periodontal disease were found to be significantly higher than in cats that recovered after treatment (P<0.001). SOD, CAT and GSH levels were determined to be significantly lower cats with periodontal disease than recovered cats (P<0.001). In conclusion, this study reveals that there is a relationship between periodontal diseases and oxidant/antioxidant balance in cats and it shows that the oxidative stress develop due to the increase of free radicals.
SOCIALIZATION OF PEOPLE WITH DISABILITIES IN THE FIELD OF PHYSICAL CULTURE AND SPORTS IN A COMPETITIVE ENVIRONMENT
Authors: Barabanova V. B. , Kopaneva E. A.
Published: May 2024

The relevance of the research lies in the analysis of the problem of creating conditions for an accessible environment for physical activity and the manifestation of their capabilities in various aspects, the inclusion of people with disabilities in the active life of society. Involving people with disabilities in inclusive sports implies training and competitive activities, participation in events as part of a panel of judges, establishing communication, as well as, taking into account personal achievements, the opportunity to participate in international competitions in professional and Paralympic sports. The main idea of involving people with disabilities in physical culture and sports is not a struggle for victory and results, but uniting people with disabilities, expanding the boundaries of their capabilities and socializing in society - this is a very important aspect of the modern society development.
This article examines currently important problem of socializing the disabled people in the field of physical culture and sports in competitive activities.
Based on theoretical research methods, we studied and systematized the factors influencing the socialization of people with disabilities in physical activity.
The article provides recommendations on how to organize work with people with disabilities, taking into account their physical and psychological conditions.
Until today, the problems of this very significant group of people have been under insufficient attention. But, with the gradual development of the society towards greater humanization, the Universal Declaration of Human Rights, the World Program of Action for People with Disabilities and the UN Standard Rules on the implementation of equal opportunities for people with disabilities were developed and adopted. Most countries have also adopted laws that draws attention to the problems faced by people with disabilities.
THEORETICAL COMPETENCIES OF STUDENTS OF A PHYSICAL CULTURE AND SPORT UNIVERSITY: WAYS OF FORMATION AND KAHOOT CONTROL
Authors: Chatinyan A.
Published: May 2024

The purpose of the research is to study the features of the methodology of performing "lectures with pre-planned mistakes" and Kahoot control of theoretical competencies of students of a physical culture and sport university.
The introduction of a modern form of lectures, «lectures with pre-planned mistakes", into the educational process of ASIPCS students allowed us to identify that during one lecture session only 3-4 planned errors are enough to make it possible to solve all the challenges facing this form of lectures. The use of audio lectures on “General Pedagogy" and "Pedagogy of Sports" in the educational process of ASIPCS showed that students reacted positively to this innovation and expressed their opinion on the expediency and use. Gamification in the process of monitoring and checking students' knowledge through the Kahoot platform has shown its advantages over the traditional form of holding seminars. The vast majority of 2nd and 3rd year students highly appreciate the use of this information and communication technology in the educational process. This platform allows you to solve not only the tasks of monitoring, controlling, mastering and consolidating new theoretical knowledge, but also provides an opportunity to develop skills of collective thinking and collective decision-making.
TÜRKİYE’DE GENÇLERİN ÇEŞİTLİ DEĞİŞKENLER AÇISINDAN ALGILARININ İNCELENMESİ- TÜRKİYE GENÇLİK ARAŞTIRMASI 2022
Authors: Baysal Tahir , Sağlam Mehmet , Kıvrak Mehmet , Kay Mehmet Akif , Şentürk Emine
Published: May 2024

Yapısal olarak değişim ve dönüşümü en hızlı yaşayan, ortaya çıkan gelişmelere en hızlı uyum sağlayan ve bu yönü ile son derece dinamik bir yapıya sahip olan gençlik, bütün dünyada anlaşılmaya çalışılmaktadır. Çeşitli kuşak tanımları yapılarak toplumun farklılaştığı bu süreçte gençleri tanımak ve anlamak daha da önem kazanmaktadır. Gençlerin eğitimden siyasal hayata, sosyal yaşamdan evlilik ve aile ilişkilerine ilişkin bakış açılarının anlaşılması onları tanımayı ve ulaşmayı da kolaylaştıracaktır. Türkiye’nin nüfus yapısı ve gençlerin bu nüfus yapısı içerisindeki önemli oranı dikkate alınarak bu çalışmada; Türkiye’de 18-25 yaş aralığındaki gençlerin, eğitim, teknoloji, çalışma hayatı, aile hayatı gibi konulardaki görüşlerinin ve beklentilerinin belirlenmesi, bahsedilen konular çerçevesinde gençlerin mevcut sosyal ve ekonomik profilinin ortaya çıkarılması amaçlanmıştır. Betimsel tarama modelinde gerçekleştirilen bu çalışma; Türkiye geneli Türkiye İstatistik Kurumu Adrese Dayalı Nüfus Kayıtları sonuçlarından 18-25 yaş aralığındaki gençlerden basit tesadüfi örneklem çekilerek elde edilen veriler kullanılmıştır. Bu kapsamda çalışma 2510 genç ile yüz yüze anketler uygulanarak gerçekleştirilmiştir. Elde edilen veriler Aile, kimlik ve değerler, Sivil toplum ve katılım, Teknoloji ve sosyal medya ve Eğitim ve istihdam alt başlıkları alanlarında analiz edilerek değerlendirilmiştir.
La reciente diversificación de los flujos turísticos internacionales hacia España
Authors: Jiménez-García Blanca Jiménez-García , García Esteban Coral
Published: May 2024

Motivación

El turismo internacional en España exhibió un elevado dinamismo en 2023, hasta situarse en máximos históricos en términos de llegadas de turistas, pernoctaciones hoteleras y gasto medio por turista. Este artículo describe las características recientes de dichos flujos turísticos, así como los factores que podrían contribuir a explicarlas.

Ideas principales

•En 2023 y principios de 2024, las llegadas de turistas internacionales aumentaron, con respecto al período 2016-2019, de manera más acusada en los meses de otoño e invierno que en el período estival.

•En 2023, las pernoctaciones hoteleras de extranjeros aumentaron con mayor intensidad, respecto al período prepandemia, en las regiones del norte de España, en comparación con los archipiélagos y el sur peninsular.

•El origen de los turistas extranjeros también se habría diversificado en 2023, con un notable crecimiento de los procedentes de América, frente al leve retroceso de los turistas provenientes de países como Alemania y Reino Unido.

•En el conjunto del año 2023, los turistas internacionales se habrían orientado en mayor medida hacia establecimientos hoteleros de más categoría, fomentando el incremento del gasto medio por turista.
Neural Toxicity And Deviating Behaviors: A Review Study
Authors: Yamani Ibrahim Abdul Jaleel , Alnaimi Izzeldeen , Alkhatib Ahed J , Alnaimi Suleiman
Published: May 2024

Background: neural toxicity can be mediated by several agents including the accumulation of heavy metal. Neural toxicity could cause deviating behaviors and violent actions. Study objectives: the main objectives of the present study were to review the literature regarding the impacts of neural toxicity on deviating behaviors and violent actions and to explore the impacts of heavy metals including lead (pb) on violent actions. Methodology: literature was reviewed for articles involved in the neural toxicity and their impacts on deviating behaviors such as violence. Articles were studied and summarized to extract the appropriate information, this helped in making up the current study. Results: reviewed literature showed that exposure to heavy metals is associated with violent behaviors and deviating actions. Previous studies indicated that prisoners had higher levels of lead (pb) compared with their counter controls. It was also shown that schoolchildren who had poor academic achievement and committed to violent actions has higher levels of lead (pb). Conclusions: violent actions and deviating behaviors have their environmental origin such as exposure to heavy metals.assessment of heavy metals may be a future indicator to evaluate persons with violent attitudes
A percepção da governança corporativa por servidores da controladoria geral do município de Goiânia
Authors: Mota Fernanda , Freitas Vailson
Published: May 2024

Este artigo aborda a utilização dos mecanismos de governança pelo órgão de controle interno do município de Goiânia como ferramenta essencial na busca para tornar a gestão municipal mais eficaz, eficiente e efetiva na execução das políticas públicas. Embora o modelo de gestão voltado as boas práticas de governança seja algo novo em termos de administração pública, a incorporação dos mecanismos de mercado e outras ferramentas de gestão privada para dentro da pública tem proporcionado importantes mudanças dentre elas a maneira com que os gestores administram os recursos públicos e abrindo novas oportunidades no processo de reforma e modernização da gestão pública. O objetivo deste estudo é identificar a aplicação dos conceitos da governança corporativa no âmbito público municipal e a sua utilização pelo controle interno desse ente federativo. A metodologia adotada comportou uma pesquisa bibliográfica e documental, visando buscar referenciais teóricos, que pudessem dar sustentação ao objeto da pesquisa. O campo de estudo limitou-se a verificação do uso da governança corporativa pelo controle interno municipal de Goiânia representado pela Controladoria Geral do Município de Goiânia. Analisando os mecanismos de governança pública: Liderança, Estratégia e Controle em conjunto, foi possível observar uma sinalização positiva do resultado geral, em especial na dimensão Controle, entretanto as práticas de governança no âmbito do controle interno do Município de Goiânia ainda se mostram incipientes, necessitando do aperfeiçoamento.
Dimensiones lentamente cambiantes en data warehouses: un análisis a través de la revisión bibliográfica
Authors: Lanzas Martínez Erick Noel
Published: May 2024

Este artículo de revisión documental examina el impacto y los desafíos planteados por las dimensiones lentamente cambiantes (SCD) en el contexto de los Data Warehouses. Destaca cómo las SCD presentan desafíos únicos para la gestión de datos y la toma de decisiones empresariales, con un enfoque en la necesidad de mantener datos históricos actualizados y coherentes. Además, se han analizado diversas estrategias de modelado utilizadas por diversos autores para sortear estos obstáculos, incluida la propuesta de Kimball y Ross (2013), así como enfoques como las Temporary Data Warehouses (TDW) y el énfasis en “Extract, Transform, and Load” (ETL). Cada estrategia se adapta a diferentes necesidades de negocio y datos, ofreciendo soluciones valiosas para abordar eficazmente el desafío de las SCD y mejorar la calidad de los datos en los Data Warehouses. Este estudio proporciona ideas valiosas para futuras investigaciones y prácticas, subrayando cómo una gestión estratégica de las SCD puede potenciar la toma de decisiones informadas en la era de la analítica empresarial.
Reporte de caso: Tricobezoar
Authors: Díaz González Jorge Alberto , Reyes Zúniga Ingrid Gabriela , Pineda Santos Misael
Published: May 2024

Reportamos el caso de una adolescente femenina que ingresa al Hospital Mario Catarino Rivas en San Pedro Sula con antecedente de tricofagia desde hace 5 años. Ingresa con historia de dolor abdominal epigástrico de 3 meses de evolución con náuseas y vómitos de alimentos ocasionales junto a pérdida de aproximadamente 6 kilogramos de peso en los últimos 3 meses.Paciente fue ingresada y se completaron estudios diagnosticándose tricobezoar gástrico con posterior intervención quirúrgica: laparotomía media supraumbilical accediendo al estómago sobre el cual se le realizó una gastrostomía antral de 6 cm de longitud por donde se extrae el bezoar en su totalidad. Se cierra posteriormente la gastrotomía.
Infecção natural por Trypanosoma evansi em cão no estado de Rondônia, Brasil: relato de caso
Authors: Oliveira Marcos José de , Anadão Liliane de Souza , Souza Fernanda dos Anjos , Santos Richardson Soares dos , Fermino Bruno Rafael , Rodrigues Carla Monadeli Filgueira , Carvalho Jeferson Silva , Gasparotto Paulo Henrique Gilio , Silva Hemelly Suldini da , Santos Francisco Glauco de Araújo
Published: May 2024

As tripanossomíases são um conjunto de doenças causadas por protozoários do gênero Trypanosoma. Entre elas, temos a surra ou mal-das-cadeiras, cujo agente etiológico é o Trypanosoma evansi, importante patógeno transmitido por moscas hematófagas, como tabanídeos e moscas do gênero Stomoxys. Além dos equinos, o T. evansi pode infectar e causar patologia importante em cães. Entretanto, há poucos relatos sobre epidemiologia, diagnóstico, patologia e terapêutica em cães no Brasil, a escassez de dados é ainda maior quando se trata de casos nos estados da Amazônia legal, como Rondônia. Este trabalho tem como objetivo relatar o primeiro caso de infecção natural por T. evansi em cão no município de Ariquemes, Rondônia, Brasil. Para tal, foram realizados exame físico do paciente e laboratoriais. Foi feito hemograma, análise parasitológica de esfregaços sanguíneos e PCR (polymerase chain reaction). A análise por microscopia de luz mostrou a presença de flagelados do gênero Trypanosoma com ausência do cinetoplasto, características das formas tripomastigotas sanguíneas de T. evansi encontradas na América do Sul. O diagnóstico para tripanossoma foi confirmado por PCR convencional. No exame físico, observou-se mucosas hiperêmicas, hipetermia, desidratação, taquicardia, dor a palpação abdominal, pelagem opaca e ptose bilateral. O hemograma evidenciou moderada anemia regenerativa, microcítica, normocrômica, além de leucopenia, linfopenia e trombocitopenia. O tratamento do paciente foi realizado, no entanto, devido à falha de execução pelo proprietário, o paciente veio à óbito. Este trabalho vem mostrar a necessidade de uma pesquisa epidemiológica criteriosa sobre T. evansi no estado de Rondônia, realizando a busca por possíveis vetores e hospedeiros vertebrados domésticos e selvagens com auxílio de ferramentas moleculares, como PCR e sequenciamento de DNA, sendo estas, indispensáveis para uma caracteriazação precisa da espécie do parasito e das cepas circulantes na região.
Estudo comparativo entre a norma NBR 14323 e os testes de incêndio em escala real
Authors: Silva José Geraldo de Araújo , Gouveia Antônio Maria Claret de , Guimarães Fernanda Ribeiro Jordão , Daumas Gustavo Oliveira , Inoue Hisashi , Araújo Lucas Teixeira
Published: May 2024

Devido às suas boas características mecânicas, além da facilidade de manuseio e montagem, nos últimos anos o aço tem apresentado uma crescente de utilização como elemento construtivo, quer seja de edifícios de andares múltiplos, galpões ou pontes. É sabido da engenharia de materiais que o acréscimo de temperatura aumenta a energia interna dos corpos, o que faz com que as suas características sejam alteradas. Para materiais dúcteis, como o aço, ocorre a diminuição dos módulos de elasticidade (módulo de Young) e da resistência à tração (tensão de escoamento), sendo que há tempos vêm-se procurando quantificar a variação dos valores destas características quando da ocorrência do aumento da temperatura. Incêndios são fenômenos aleatórios que não se repetem com a mesma tipologia uma vez que os fatores envolvidos são sempre diferentes, o que impossibilita a elaboração de uma norma técnica que cubra todas as reações que podem acontecer durante um sinistro. A curva padronizada temperatura-tempo adotada na ABNT NBR 5628:2001 (igual à curva ISO 834) simula o aumento da temperatura em um ambiente em função do tempo quando da ocorrência de um incêndio, visando obter a temperatura (teórica) dos elementos estruturais a partir da elevação da temperatura dos gases presentes no interior do local onde ocorre o incêndio. A verificação da estabilidade estrutural sob alta temperatura adota o valor da temperatura obtido através da curva padrão e dos preceitos normativos presentes na norma ABNT NBR14323:2013, que adota conceitos de perda das características mecânica (resistência e módulo de elasticidade) do aço sob alta temperatura obtidos nos anos 1980, utilizando técnicas que hoje estão obsoletas. Este trabalho comparará os valores propostos pela referida norma com os resultados obtidos durante a realização e monitoramento de incêndios em escala real.
Ética e responsabilidade social: uma perspectiva responsável
Authors: Ferreira Vellyan José dos Santos , Fonseca Marcello Pires , Lima Francisco Lucio Pinto de , Craveiro Eliane Gonçalves , Silva Marinilson Rodrigues da , Pessoa Sergio da Silva , Moçambite Viviane da Silva Costa Novo , Correia Filho Wlademir Leite
Published: May 2024

O presente estudo tem como principal propósito investigar o papel da ética e da responsabilidade social no contexto das organizações contemporâneas. Para atingir esse objetivo, uma extensa pesquisa bibliográfica foi realizada, compreendendo uma análise detalhada de obras e textos de renomados autores, além de artigos científicos e teses pertinentes ao tema. Os materiais selecionados foram criteriosamente extraídos de plataformas acadêmicas como scielo e google acadêmico, garantindo a qualidade e relevância das fontes utilizadas. A análise efetiva desses recursos proporcionou uma visão abrangente dos estudos relacionados à ética e responsabilidade social em seu contexto empresarial atual, revelando suas implicações e contribuições. Verificou-se que a prática desses valores não apenas beneficia as organizações em si, mas também são responsáveis por impactos positivos na comunidade local, na sociedade em geral e em seus clientes. Uma das conclusões destacadas é que a adoção de práticas éticas e responsáveis não é apenas uma questão de cumprimento de normas e regulamentos, mas também uma estratégia inteligente para o sucesso sustentável das organizações. Além de promover a confiança e a credibilidade junto aos stakeholders, essas práticas têm o potencial de gerar vantagens competitivas, fortalecendo a imagem da empresa e favorecendo sua perenidade no mercado. Assim, a pesquisa valida a relevância e o impacto positivo da prática ética e responsabilidade social no contexto empresarial moderno, ao evidenciar os amplos benefícios associados a essas práticas, utilizando se como um incentivo para uma reflexão mais profunda e uma ação proativa por parte das organizações, visando um futuro mais ético, sustentável e socialmente responsável para todos os envolvidos.
Creación o destrucción de valor en el sector financiero colombiano
Authors: Tole González Luisa Fernanda , Naranjo Acosta William Guillermo
Published: May 2024

La construcción de valor empresarial es importante porque nos permite comprender el impacto que la gerencia le está contribuyendo en la maximización de recursos y la sostenibilidad del ente económico en el tiempo.
 
En ese sentido, analizar la construcción o destrucción de valor en las unidades de negocios es fundamental para lograr estrategias financieras que permitan optimizar los recursos escasos y en especial, la generación de nuevas prácticas a la compañía.
 
Comprender los resultados financieros y en especial, la incorporación de distintos métodos para valorar empresas en el mercado, es crucial para lograr consolidar los negocios en las condiciones actuales, en ese sentido, la aplicación del análisis financiero moderno permite mejorar la toma de decisiones en el nivel gerencial, para con ello, mejorar en el diseño de medidas que maximicen el valor de la empresa en el mercado.
 
El objetivo general de la investigación es; determinar el nivel de construcción de valor en el sector financiero colombiano, los objetivos específicos son: analizar la estructura del capital de las empresas del sector financiero que cotizan en BVC y analizar el comportamiento del riesgo y retorno del sector financiero en Colombia.
 
La investigación se desarrolló mediante un enfoque cuant itativo de tipo descriptivo, en la cual se tomaron los resultados financieros de los bancos que cotizan en la BVC, con la información de la bolsa se construyó el análisis del modelo CAPM, el WACC y el EVA con el fin de lograr establecer la construcción de valor del sector financiero perteneciente al mercado de capitales colombiano.
 
La investigación evidenció en primer lugar, que la acción de BanColombia fue la de mayor retorno esperado con un valor de 36,01% EA, seguida de BBVA (14,13% EA) y, en tercer lugar, Preferencial Bancolombia (6,64%EA), igualmente, el activo con mayor beta fue Bancolombia (1.26) y el de menor beta fue BBVA (0.16). al analizar el riesgo se destaca que la acción de mayor riesgo es BBVA (2,82%) mientras la de menor riesgo fue AVIVIENDA (1,77%). Finalmente, se destaca que el activo del sector financiero de mejor comportamiento en 2022 fue la acción de Bancolombia.
Estrategia de Venta y Marketing de Operadores Turísticos (Caseteros) en el Sector de Playas de la Rosita de Puerto Colombia, Atlántico
Authors: Padilla González Fredys , Adarraga Mejía2 Javier Enrrique , Hernández Olmos3 Roberto , Ariza Molina Flor Manuela
Published: May 2024

Este estudio pretende determinar la estrategia de venta y marketing de operadores turísticos (caseteros) en el área de playas de la Rosita de Puerto Colombia, Atlántico, aplicando una muestra aleatoria simple a los 30 caseteros u operadores turísticos que se encuentran a lo largo de los 300 metros aproximados de playa. La investigación emitió resultados producto de los datos surtidos en las visitas al sector y por la encuesta aplicada y analizada a esta parte comercial de playa; los locales comerciales (casetas) son de su propiedad, los cuales han heredado de generaciones anteriores, así como el ejercicio de esta modalidad comercial; entre los productos que comercializan, se encuentran comidas típicas de la costa norte colombiana donde prevalece el pescado, cocteles de mariscos, arroces, patacones, bebidas naturales (limonada, agua de panela, entre otros) y bebidas industrialmente embotelladas; la estrategia de mercadeo que sobresale con relación a los productos que comercializan es el voz a voz; como estrategia de venta figuran los descuentos que hacen a grupos de visitantes o compras por cantidad; existen variedad de proveedores de insumos para surtir sus locales; como medio de recaudo utilizan el dinero en efectivo, recientemente, están implementando transacciones por medios digitales; gran parte de los caseteros, son oriundos de Puerto Colombia y otros de poblaciones vecinas; esta experiencia comercial tradicional, se constituye en uno de los medios de ingresos económicos de perspectivas positivas para estos operadores turísticos.
Cytological abnormalities in Artemisia pallens Wall. induced by gamma rays
Authors: Rekha K. , Kak S. , Langer Anima
Published: May 2024

The effect of gamma rays on Artemisia pallens Wall. have been studied with reference to behaviour of chromosomes and frequency of cytological abnormalities. Various mitotic and meiotic irregularities were studied in m1 plants raised from seeds of A. pallens treated with gamma rays at various doses like 150, 200, 250, 300, 350, 400 and 500 gy. gamma rays caused a dose dependent increase and decrease in mitotic inhibition and mitotic index respectively. From these treatments, a significant percentage of chromosomal abnormalities such as formation of univalents, fragments, stickiness, chromatin bridges with or without laggards were induced. The total percentage of cells with chromosomal aberrations increased with increase in dose.
Analysis of Grotowskis Body Action Method from the Perspective of Zhuangzi
Authors: Shen Dianhuai
Published: May 2024

Jerzy Grotowski (1933-1999, hereinafter referred to as Grotowski) was a renowned theater practitioner in the 20th century, dedicating his life to the study of theatrical performance. His theatrical works shook the world in the 20th century, and he was well-known in the theater communities of Europe and America. Unfortunately, he passed away prematurely, leaving behind profound and abstruse writings for future generations. His late-life creation, the Art of Vehicle in body action methods, holds profound significance for the study of states in various artistic performances. Based on this, researchers, drawing on Grotowskis lifelong learning and research background, interpret and analyze Grotowskis study of art of vehicle through the Zhuangzis concept of body in the philosophy of Swiss philosopher Jean Franois Billeters dynamic mechanism. This paper is based on the research theory of Professor Mingder Chung from Taipei National University of the Arts on Grotowskis MPA, aiming to elucidate Grotowskis interpretation of body through Zhuangzis body view, and further clarify the conceptual framework of MPA. The purpose is to contribute theoretical foundations to the study of Grotowskis Art of Vehicle.
Exploring the Impact of Neo-Confucianism on Material Art Through the Artistic Characteristics of Kesi in Song Dynasty
Authors: Wu Yu , Wang Chengzhe
Published: May 2024

The Song Dynasty was a period of great development in ancient Chinese art, including material art. Kesi, a type of material art is taken as an instance to explore how Neo-Confucianism influenced the development of art during the Song dynasty, a period marked by new developments in thought and culture. Neo-Confucianism impacted not only the political realm but also the art of painting, and further had a significant influence on the composition, coloring, and techniques of silk textile. The ornamental kesi taperstry paintings of the Song dynasty as a material artistry, similar with the style of flower and bird paintings of the period, focused on the realistic depiction of objects, using silk as a substitute for the brush. With image analysis, historical document research, and the corroboration between documents and physical objects, this article elucidates the artistic characteristics of kesi (silk tapestry) under the influence of the "investigation of things to extend knowledge" philosophy in Song dynasty.
The Continuation of Incense Worship: Exploring the Rituals of Ancestral Belief in the Incense Worship Culture from the Perspective of Chinese Transmission
Authors: Li Yuchen
Published: May 2024

Incense worship refers to the incense or candlelight used for worshipping ancestors or deities, which is an indispensable part of traditional Chinese culture. With the succession of generations and the evolution of culture, the term incense worship has gradually developed more connotations, among which the evolution based on clan implications is particularly characterized by localization. This paper will deeply explore the connotations of incense worship from the perspective of Chinese transmission, tracing its evolution in the context of ancestor worship and the localization of clan traditions. At the same time, from the perspective of communication studies, it analyzes its metaphor as a form of communication, glimpsing the rituals of ancestral belief in the incense worship culture through exploration of media, ceremonies, and space, and discussing its modern continuation and changes.
How pre-trained large model can help, when SAM meets image restoration
Authors: Ping An
Published: May 2024

In the process of image capture, degradation is inevitable due to noise, motion, down-sampling and so on. Therefore, image restoration is essential to improve the quality of images to enhance their visual effects and benefit downstream tasks. Adding prior knowledge can help the model better understand the image content and restoration requirements, thus improving the quality and efficiency. Semantic-level prior information can be generated by pre-trained large-scale models, such as segment anything models (SAM), and applied to a large number of downstream tasks. SAM has demonstrated powerful robustness and stability in restoration tasks, such as denoising, super-resolution, low-light enhancement, etc. Meanwhile, as an interactive component, SAM brings more control for users during the repair process. In this paper, we focus on the importance of SAM as prior information and systematically summarize a series of recent works combining SAM prior and low-level image restoration from three perspectives. In addition, we have summarized some potential problems and future directions of SAM.
Optimization of substation enclosure performance and carbon emission analysis based on OED
Authors: Jiahui Yu , Jianwei Ren , Xueyuan Zheng , Huifeng Hu , Puyan Wang , Ranran Bi
Published: May 2024

To explore the thermal performance parameters of substation enclosure parameters and interaction and influence degree, using the DeST software simulation and orthogonal test method to building load minimum as the target parameters, select external wall heat transfer coefficient, roof heat transfer coefficient, outer window heat transfer coefficient and orthogonal test factors, carry out the four factors three level L9 (34) Orthogonal test analysis, studied the influence of each factor and its interaction on the building load, and finally obtained the optimal combination of factors under the comprehensive boundary conditions. At the same time, the correlation between load and outdoor temperature in the optimal scheme of unmanned substation and the carbon emission results before and after optimization are also explored. The results show that through univariate analysis, with the heat transfer coefficient of exterior wall, roof and window, the cumulative cooling load is not linear. Through the orthogonal experimental analysis, the significance of substation building is> roof exterior wall> south Angle> window, and the optimal is A1-B1-C2-D2The annual cumulative building cooling load is 20165.59 kW h, and the peak cooling load appears on July 24. The operating condition of 0 ~ 9kW accounts for 90.6% of the annual operating time. There is a strong linear correlation between the building cooling load and the outdoor temperature (R2=0.65), the energy saving rate of the final optimized scheme is 17.71%, and the carbon saving rate is 26.72%. The research content of this paper provides reference for the renovation of existing buildings and the design of new buildings in substation buildings.
Comparison between traditional vacuum booster and electro-mechanical braking system
Authors: Gao Ze
Published: May 2024

The Electro-Mechanical Braking System (EMB) is an innovation in the energy supply and transmission of the brake drive mechanism. It provides braking energy with a motor and transmits the driver's braking intention with an electrical signal, and the actuator is still a conventional brake. The automotive electronic mechanical system is in line with the three major themes of safety, energy saving, and environmental protection, and is the development direction of the future brake system. Its research is still in the experimental stage, and there is still some distance from the product launch. Therefore, by comparing the structure and principle of the traditional vacuum booster and the Electro-Mechanical brake system, this paper analyzes their respective advantages and disadvantages, and finally points out that under the current background, the research and development of the Electro-Mechanical brake system is still immature, because its structure is more compact and complex, it is more difficult to conduct simulation, and it still needs to increase research and development investment.