bluuebunny/crossref_metadata_2025 huggingface dataset:
The Histone Demethylase KDM5 Is Essential for Larval Growth in Drosophila
Authors: Drelon Coralie , Belalcazar Helen M , Secombe Julie
Published: May 2018

Regulated gene expression is necessary for developmental and homeostatic processes. The KDM5 family of transcriptional regulators are histone H3 lysine 4 demethylases that can function through both demethylase-dependent and -independent mechanisms. While loss and overexpression of KDM5 proteins are linked to intellectual disability and cancer, respectively, their normal developmental functions remain less characterized. Drosophila melanogaster provides an ideal system to investigate KDM5 function, as it encodes a single ortholog in contrast to the four paralogs found in mammalian cells. To examine the consequences of complete loss of KDM5, we generated a null allele of Drosophila kdm5, also known as little imaginal discs (lid), and show that it is essential for viability. Animals lacking KDM5 show a dramatically delayed larval development that coincides with decreased proliferation and increased cell death in wing imaginal discs. Interestingly, this developmental delay is independent of the well-characterized Jumonji C (JmjC) domain-encoded histone demethylase activity of KDM5, suggesting key functions for less characterized domains. Consistent with the phenotypes observed, transcriptome analyses of kdm5 null mutant wing imaginal discs revealed the dysregulation of genes involved in several cellular processes, including cell cycle progression and DNA repair. Together, our analyses reveal KDM5 as a key regulator of larval growth and offer an invaluable tool for defining the biological activities of KDM5 family proteins.
Kinesiology Culture in the Education of the Modern Child / Kineziološka kultura u odgoju i obrazovanju suvremenog djeteta
Authors: Prskalo Ivan
Published: May 2018

AbstractContemporary lifestyle has significantly changed compared to that in the past. The role of educational systems, which are a kind of social leverage, is to provide responses to the changes that have affected the younger generations of today because that is what their preparation for life really implies. The response to challenges of the modern life, which are also reflected in the life of every human from the earliest and most vulnerable age, is the kinesiology content, which can reduce any negative repercussions of such a state through increased physical activity. An individual has no power to change the living conditions, but (s)he has the power to adjust and to optimally respond to them. By stressing the positive effects of exercise, an emphasis is also placed on the comprehensiveness in relation to the development of environmental and ethical awareness, and the culture of leisure time while simultaneously ensuring optimal number of hours of Kinesiology culture at all levels of education.Key words: child; education; kinesiology; kinesiology culture; upbringing.---SažetakNačin života danas je znatno promijenjen u odnosu na način života u prošlosti. Zadaća obrazovnih sustava, svojevrsnih društvenih poluga, jest dati odgovore na promjene koje će zahvatiti i sadašnje najmlađe generacije, jer je to smisao njihove pripreme za život. Odgovor na izazove suvremenog svijeta, koji se nužno odražavaju na život čovjeka od najranije i najranjivije dobi, jest kineziološki sadržaj koji uz povećani aktivitet može umanjiti negativne posljedice takvog stanja. Pojedinac nema moć promjene životnih uvjeta, ali ima moć prilagodbe i optimalnog odgovora. Naglašavajući pozitivne učinke vježbanja, ističe se i sveobuhvatnost u odnosu na razvoj ekološke, etičke svijesti i kulture slobodnog vremena, uz istodobno imperativno osiguranje optimalne satnice kineziološke kulture na svim razinama odgoja i obrazovanja.Ključne riječi: kineziologija, kineziološka kultura, odgoj, obrazovanje, dijete.
Pedro El Grande y Vladimir Putin: comparación del expansionismo en la identidad nacional rusa
Authors: Gólcher Barguil Erika
Published: May 2018

En esta investigación nos proponemos identificar y analizar los intereses nacionales rusos a partir de una serie de variables presentes en su historia desde el reinado de Pedro el Grande. Esto nos llevará a comprender los elementos del expansionismo en la conformación de la identidad nacional rusa y podremos destacar que los mismos siguen presentes en los gobiernos de Vladimir Putin, a pesar de la diferencia de siglos.  Con estos elementos tenemos una nación que justifica su expansionismo en la necesidad de garantizar la seguridad de un país que no tiene fronteras naturales y cuyas salidas a los mares deben ser defendidas. El expansionismo se basa en una identidad nacional que hace referencia al excepcionalismo ruso como la verdadera heredera del Imperio Romano y la elección de Moscú como la tercera Roma y defensora de la cristiandad ortodoxa.
La plegaria de Chernóbil: memoria del desastre nuclear en el contexto de un poder agonizante
Authors: Agüero García Javier
Published: May 2018

Este ensayo constituye una interpretación acerca de la memoria asociada a los efectos causados por el accidente nuclear ocurrido en Chernóbil en 1986, catalogado como el más devastador de la historia.  A partir de los relatos contenidos en la obra Voces de Chernóbil, escrita por Svetlana Alexiévich, se aborda primero los desencantos de una ciencia que había prometido bienestar, mediante el desarrollo del uso civil de la energía atómica; segundo, el cambio inevitable en la vida de una sociedad anonadada por el impacto dantesco de una explosión sin parangón; tercero, la persistencia de las estructuras autoritarias, empeñadas en ocultar y en engañar a las personas acerca de lo ocurrido; y cuarto, el costo del heroísmo encarnado en bomberos, liquidadores y soldados que dieron su vida para evitar una desgracia mayor; y quinto, los clamores de los inocentes, sufrientes frente a la adversidad, comprendidos solo en el seno de la familia más inmediata.  Finalmente, se esbozan los dilemas existenciales expresados por los testigos del desastre ocurrido en Ucrania que constituyó un preámbulo de la debacle de la Unión Soviética, un imperio agonizante conforme avanzaba el decenio de 1980.
Políticas y discursos anti comunistas en la Costa Rica de la posguerra, 1948- 1949
Authors: Barrientos Valverde Jorge
Published: May 2018

Veremos a continuación un análisis de las políticas y discursos anti comunistas de los representantes políticos que estuvieron en el poder del Estado directamente o como colaboradores entre 1948 y 1949, siguiendo el desarrollo del gobierno de la Junta figuerista, que participó en ese contexto. Esto a través de sus pronunciamientos oficiales en diferentes escritos publicados individualmente y en prensa, además de fuentes oficiales de gobierno, principalmente leyes y decretos, memorias de ministerios y de la asamblea legislativa, discursos presidenciales, etc. Lo anterior bajo la lógica de centrarse en el argumento anti comunista basado en la defensa de la democracia occidental, el capitalismo, las costumbres occidentales, y los Derechos Humanos desde el Estado y su respectivo gobierno. En esa dirección examinaremos a manera comparativa las justificaciones anti comunistas para analizar sus posiciones ideológicas, sus políticas públicas, acciones represivas y sus decisiones de acuerdo a las diferentes problemáticas que se les presentaran en torno a la amenaza comunista.
El Conocimiento de los Jóvenes del Liceo Experimental Bilingüe de Grecia acerca de los Teratógenos y su efecto en los embriones humanos
Authors: Quirós Vargas Elsie , Téllez Quirós Jared
Published: May 2018

El presente escrito analiza varias sustancias denominadas teratógenos, sus consecuencias en el feto humano y el nivel de conocimiento de los estudiantes de 16 y 17 años del Liceo Experimental Bilingüe de Grecia sobre dichos agentes. Se excluye el alcohol, tabaco y drogas callejeras del estudio debido a la abundante publicidad anti-consumo de éstos durante el embarazo. La finalidad fue que la población demostrara su nivel de entendimiento acerca del tema, se destacaran los químicos peligrosos, se aplicara un cuestionario para determinar dicho grado de instrucción, y que se identificaran los productos de uso diario que contienen estos elementos. En conclusión, las materias teratogénicas están en una variedad de artículos artificiales y la exposición a éstos es nociva para la formación neonatal. La mayoría de jóvenes que participaron desconocen al teratógeno, sus implicaciones en la gestación, cómo reconocerlo y además, viven en zonas que pueden ser afectadas por ingredientes teratogénicos
Presentación del Dossier: Religión y política en el mundo antiguo y contemporáneo
Authors: Espinoza Rivera Jerry
Published: May 2018

A lo largo de la historia, la relación entre religión y política ha sido escabrosa y conflictiva. Ha sido una relación de encuentros y malentendidos, pero también de sometimiento y complicidad.En las sociedades antiguas, en las que predominaba la heteronomía y escaseaba la autonomía, la religión ocupaba un lugar prominente, ya que ésta era la garante de la ley y del “orden natural de las cosas”. Por esta razón, cuestionar la autoridad del emperador o del faraón en Sumeria, en Egipto o en Persia constituía un gravísimo delito, pues literalmente significaba cuestionar el orden establecido por los dioses. Se estableció así una estrecha alianza entre el poder político y los sacerdotes.
Apocalyptic Trends in Contemporary Politics
Authors: Marega Stella
Published: May 2018

The symbol of apocalypse contains strong political connotations linked to eschatological expectations: the faith in a divine intervention on the course of history has often generated social instability, outbreaks of violence, and ideological claims.This article aims to demonstrate as the overlap between apocalyptic symbolism and political phenomena is still ongoing, even assuming new critical implications in connection with recent geopolitical dynamics on a global scale.The detection of the apocalyptic trends is supported by a historical premise, a brief summary of theoretical perspectives, and three study cases: the presence of messianic aspects in US imperialism, the influence of the doctrine of the Hidden Imam in the Iranian politics during the Ahmadinejad presidency, and the use of apocalyptic prophecies in the Islamic State’s propaganda
Fracture Strength and Precision of Fit of Implant-Retained Monolithic Zirconia Crowns
Authors: Moilanen Pauliina , Hjerppe Jenni , Lassila Lippo V. J. , Närhi Timo O.
Published: May 2018

New monolithic zirconia materials can be used to fabricate full-contour fixed dental prostheses with the computer-aided design/computer-aided manufacturing (CAD/CAM) method. The aim of this study was to examine the fracture strength and precision of fit of screw-retained monolithic zirconia crowns made directly on implants or by cementing on prefabricated titanium (Ti) bases. Monolithic screw-retained implant crowns (n = 6) were produced by CAD/CAM method using partially (PSZ) and fully stabilized (FSZ) zirconia. Industrially produced zirconia crowns were used as a reference. A lateral incisor study model was made onto an implant replica. Crowns were produced either directly on the implant or through cementing on a prefabricated titanium base (PSZ+Ti, FSZ+Ti). The crowns were tightened to implant replicas with a torque of 35 Ncm. The gap between the replica and the abutment or crown was measured from ×400 scanning electron microscope images for precision of fit. Mechanical testing until failure was completed with a universal testing machine with loading angle of 45°. Statistical analysis was performed (analysis of variance). Mean (±SD) failure loads were 259 ± 23 (PSZ), 140 ± 13 (FSZ), 453 ± 25 (PSZ+Ti), 439 ± 41 (FSZ+Ti), and 290 ± 39 (Procera). Mean (±SD) gap values were 2.2 ± 0.2 (PSZ), 2.5 ± 1.0 (FSZ), 7.0 ± 1.0 (PSZ+Ti), 7.7 ± 1.6 (FSZ+Ti), and 6.7 ± 1.7 (Procera). Monolithic zirconia crowns with a Ti base clearly show higher fracture strengths than the crowns fixed directly on the implant surface. Better marginal fit can be achieved with direct zirconia crowns than with crowns on a titanium base or industrially produced zirconia crowns.
Can More Housing Supply Solve the Affordability Crisis? Evidence from a Neighborhood Choice Model
Authors: Anenberg Elliot , Kung Edward
Published: May 2018

We estimate a neighborhood choice model using 2014 American Community Survey data to investigate the degree to which new housing supply can improve housing affordability. In the model, equilibrium rental rates are determined so that the number of households choosing each neighborhood is equal to the number of housing units in each neighborhood. We use the estimated model to simulate how rental rates would respond to an exogenous increase in the number of housing units in a neighborhood. We find that the rent elasticity is low, and thus marginal reductions in supply constraints alone are unlikely to meaningfully reduce rent burdens. The reason for this result appears to be that rental rates are more closely determined by the level of amenities in a neighborhood—as in a Rosen-Roback spatial equilibrium framework—than by the supply of housing.
Sport Commitment, Occupational Commitment and Intent to Quit Among High School Sports Officials
Authors: Barnhill Christopher R. , Martinez J. Michael , Andrew Damon P. , Todd Wes
Published: May 2018

This study sought to examine the issue of attrition among high school sport officials by exploring turnover intentions through the lenses of occupational and sport commitment. A questionnaire was distributed via email to high school sport officials in the southeastern United States. The data was analyzed via hierarchical multiple regression, revealing that affective occupational commitment and sport commitment are negatively correlated predictors of occupational turnover intentions. Implications for practitioners and avenues for future scholarship are conferred.
Formation and Function of a Collegiate Athletics Sustainability Committee
Authors: McCullough Brian P. , Kellison Timothy , Wendling Elodie
Published: May 2018

Institutions of higher learning may be considered dual-identity organizations because of the perceived distinctiveness between universities’ academic and athletic missions. One way in which these barriers can be weakened is through cross-sector social partnerships (CSSP), a form of collaborative engagement aimed at achieving a common societal goal. In this study, we examine the formation of a university-directed CSSP focused on enhancing environmentally sustainable initiatives within the athletic department. Interviews with 11 members of a so-called Green Team illustrate the processes of boundary spanning and boundary blurring. As demonstrated in the article, boundary spanning occurred under the leadership of a “champion” who assembled a team of stakeholders to assist with the major renovation of a pro-environmental football stadium. Though the sustainability committee has a common goal, not all experiences of Green Team members have been the same. In light of these differences, we identify key barriers and prescribe solutions that can lead to the realization of a new organizational form.
“Buralarda yabancı yok”: Hemşehri derneklerinin kentlileşme üzerine etkisi, Ankara'daki Oflular örneği
Authors: Öksüz Muhammet
Published: May 2018

Türkiye 1950’lerden beri hızlı bir kentlileşme süreci yaşamaktadır. 1950’lerde kırda yaşayan nüfus %75 iken bugün nüfusun % 92’si il ve ilçe merkezlerinde yaşamaktadır. Bunun sonucunda kent merkezlerinde aşırı bir nüfus baskısı oluşmuştur. Göçle beraber kentlileşme sorunları ortaya çıkmış ve bu sorunların çözümü için de bir tampon mekanizması görevi gören hemşehri dernekleri kurulmuştur. Hemşehri derneklerinin göçün ilk dönemlerinde adaptasyonu kolaylaştırdığı sonraki dönemlerde ise kentlileşme sürecini yavaşlattığına dair görüşler vardır. Bu çalışma Ankara’ya Karadeniz Bölgesi’nden göç edenlerin kurdukları dernekler arasında ilk sıralarda yer alan Trabzon dernekleri içindeki Of ilçesinden gelenlerin kurduğu hemşehri dernekleri üzerinedir. Bu derneklerin göç sürecinde ve sonrasında göçmenlerin kentlileşme süreçlerini nasıl etkilediğini konu edinmektedir. Bu bağlamda, göçmenlerin kentsel aidiyetlerinin gelişiminde, köken bölgeyle ilişki kurma biçimlerinde, köken bölgeye ait kırsal pratiklerin kent kültürüne aktarımında ve bu aktarımın niteliğinin değişiminde derneklerin rolünün kuşaklararası farklılıklar gözetilerek tartışılması amaçlanmaktadır. Bu amaçla “Of” adı altında Ankara’da kurulmuş olan derneklerin üyelerinden 10 kişiyle derinlemesine yarı yapılandırılmış görüşme yapılmıştır. Bunlar arasında “anahtar görüşmeci” olarak üç tane dernek yöneticisi bulunmaktadır. Görüşmeler boyunca ses kaydı yapılmış, ses kayıtları çözümlenmiş ve içerik analizi yapılmıştır. Kentlileşme süreci, pek çok farklı faktöre bağlı olarak gelişmektedir ve bu faktörler arasında yer alan kurumsal destek mekanizmalarının yani derneklerin rolü, bu mekanizmaların etkinlik alanı genişledikçe artmaktadır. Bu çalışma, bir bütün olarak kentlileşmeyi, dernekler üzerinden okuma iddiası taşımamakla birlikte, derneklerin özellikle göçün ilk dönemlerinde etkin bir ara mekanizma olduğunu kabul ederek, göçmenin kentteki birincil pozisyonunu belirleyen bir çerçeve sunduğunu iddia etmektedir.  Bununla birlikte kuşaklararası farklılıkların gelişimi yanında derneklerin Türkiye’de yerel yönetimlerin güçlendirilmesine yönelik politikalardan etkilenerek dönüştükleri söylenebilir. Çalışma sonucunda, bu derneklerin Ankara’daki Ofluların kentlileşme süreçlerinde bir ara kurum olarak çalıştığı anlaşılmıştır. Dernekler, özellikle ilk göçmenlerin belirli kentsel alanlarda ve iş kollarında kümelenmelerine neden olmuşlardır. Ancak sonraki kuşaklarda eğitim düzeyinin artması, topluluğun derneklerle ilişkilerinde kuşaklararası farklılıkların oluşmasına neden olmuştur.
New-Media Arts Protocol to study Stem Cells (NMAP-SC) v1
Authors: Diaa Ahmed Mohamed Ahmedien Dr.
Published: May 2018

This protocol aims at building amethodological synthesis to understand cancerous cells not only bybio lab’s facilities but also by new-media arts lab’s tools, applications,and vision. The template illustrates potential technical, conceptual,and aesthetic inputs derived from the new-media arts lab. On the otherhand, three output channels have been emphasized to contribute to thecore of the stem cells research, public engagement, and the core of theresearch in new-media arts.
During data acquisition v6
Authors: Snoek Lukas , Beemsterboer Tinka
Published: May 2018

This protocol lists all the steps necessary to run your MRI experiment/data acquisition safely and in a way that yields high-quality data. Moreover, if you use the centre's QC/preprocessing service, it lists the steps necessary to make sure we can convert the data into BIDS and run them through the QC/preprocessing pipelines.
Pilates vs. aerobic training for individuals who are overweight/obese v2
Authors: Rayes Angeles , Andre Barbosa de Lira Claudio , Borges Viana Ricardo , Luiz Vancini Rodrigo , Mascarin Naryana , Santos Andrade Marilia
Published: May 2018

Objective: To compare the effects of Pilates and aerobic training on cardiorespiratory fitness, isokinetic muscular strength, body composition, and functional tasks outcomes for individuals who are overweight/obese. Design: A prospective study. Settings: University laboratory and Pilates Studio. Participants: Sixty participants were divided into three groups: Pilates (n=22), Aerobic (n=21) and Control (n=17) groups. Interventions: The Pilates and Aerobic groups attended 60-min exercise sessions, three times per week for 8 weeks. The Aerobic group performed walking training at heart rate corresponding to the ventilatory threshold. Pilates groups performed exercises on the floor, on the resistance apparatus, and 1-kg Dumbbells. The control group received no intervention. All three groups were evaluated before and after 8 weeks of training. Results: There was no significant difference pre and post intervention in calorie intake [F(2, 57)=0.02744, p=0.97)]. A significant improvement of oxygen uptake at ventilatory threshold (p=0.001; d=0.60), respiratory compensation point (p=0.01; d=0.48), and maximum effort (p=0.01; d=0.33) was observed only in the Pilates group. Isokinetic peak torque for knees flexor and extensor muscles did not change for any groups. Lean mass (p=0.0005; d=0.19) and fat mass (p=0.0001; d=0.19) improved only in the Pilates group. Circumference measurements (waist and hip) decreased similarly in both experimental groups. Abdominal test performance improved more in the Pilates group (p=0.0001; d=1.69) than in the Aerobic group (p=0.03; d=0.95). Trunk extensor endurance and flexibility improved only in the Pilates group (p=0.0003; d=0.80 and p=0.0001; d=0.41, respectively). The Pilates group showed greater improvement on the chair and stair tests (p=0.0001; d=1.48 and p=0.002; d=0.78, respectively) than the Aerobic group (p=0.005; d=0.75 and p=0.04; d=0.41, respectively). Conclusion: Pilates training can be used as an alternative physical training method for individuals who are overweight/obese since it promotes significant effects in cardiorespiratory fitness, body composition, and functional tests performance.
Vinculação aos pais e relação amorosa: Papel mediador dos conflitos interparentais em jovens adultos
Authors: Pinheiro Mota Catarina , Martins Carine
Published: May 2018

A qualidade das relações estabelecidas precocemente com as figuras primordiais de afeto mostram-se de extrema relevância no desenvolvimento físico e emocional dos jovens. O desenvolvimento de bases seguras sugerem maior disponibilidade para o estabelecimento de relações fora do seio familiar, nomeadamente com o par amoroso. O presente estudo tem como objetivo analisar a qualidade de vinculação aos pais e testar o seu efeito na vinculação amorosa em jovens adultos, assim como, testar o papel mediador dos conflitos interparentais na associação anterior. A amostra foi constituída por 505 indivíduos com idades compreendidas entre os 18 e os 25 anos de idade. Os resultados apontam para um efeito preditor positivo da qualidade de laço emocional aos pais face à qualidade de vinculação ao par amoroso. Observa-se, ainda, que a perceção de conflitos interparentais exercem um papel mediador na associação entre a vinculação aos pais e a vinculação amorosa.
Preditores da empatia dirigida a humanos e outros animais em portugueses e anglo-saxónicos
Authors: Emauz Ana , Gaspar Augusta , Esteves Francisco
Published: May 2018

A relação entre empatia dirigida a humanos (EDH) e empatia dirigida a outros animais (EDA) tem sido reportada como fraca, sendo pouco conhecidos os fatores que predizem a segunda. Neste estudo examinámos potenciais variáveis preditoras de cada uma das duas formas de empatia, e comparámos participantes lusófonos e anglo-saxónicos, inspeccionando possíveis especificidades culturais. Conduzimos  um inquérito na web que incluiu versões portuguesa e inglesa duma escala de EDH, e duma escala de EDA, bem como questões relacionadas com animais de estimação, religião, dieta e participação em ONGs. A testagem de modelos de regressão múltipla mostrou que na EDH o género foi o único preditor, e apenas no grupo lusófono. O sexo feminino e a vivência com animais de estimação são preditores de EDA em ambos os grupos. Estar ligado a uma associação/ONG é um preditor na população lusófona, enquanto que na anglo-saxónica pesa mais a dieta vegetariana/vegana.
Escola e instituição
Authors: Pinheiro Mota Catarina , Costa Mónica , Mena Matos Paula
Published: May 2018

O presente estudo testa o efeito preditor da qualidade da ligação a figuras significativas (professores, funcionários da escola e da instituição) no desenvolvimento do autoconceito dos jovens. Pretende-se ainda testar o efeito mediador da qualidade da ligação aos pares e o efeito moderador do tempo de acolhimento residencial nesta associação. A amostra é composta por 400 jovens em acolhimento residencial entre os 12 e 18 anos de ambos os sexos, em Portugal. Os resultados sublinham a importância da qualidade da ligação às figuras significativas de afeto para o de um autoconceito positivo. A ligação aos pares mostra-se relevante corroborando o papel mediador no desenvolvimento do autoconceito. O tempo de acolhimento residencial não se mostrou significativo na relação entre a qualidade da ligação estabelecida com os adultos significativos e o autoconceito. À luz da teoria da vinculação realça-se a importância das ligações seguras entre adultos e jovens.
5. Sınıf Öğrencilerinin Zirai ve Organik Gübre Kullanımı Konusundaki Farkındalıklarının İncelenmesi: Bir Eylem Araştırması
Authors: CEBESOY Ümran Betül , AYAZ Büşra
Published: May 2018

Bu araştırmanın amacı; eylem araştırması yaklaşımını kullanarak ortaokul 5.
sınıf öğrencilerinin zirai ve organik gübre kullanımı konusundaki
farkındalıklarının incelenmesidir. Araştırmanın çalışma grubunu, 2016-2017
eğitim öğretim yılında Uşak ilinde bir özel okulda 5. sınıfta öğrenim görmekte
olan 13 öğrenci oluşturmaktadır. Araştırmada, 5. sınıf “toprak kirliliği”
konusunda yer alan kazanıma uygun olacak şekilde zirai ve organik gübre
kullanımına yönelik bir ders planı geliştirilmiş ve uzman görüşü doğrultusunda
gerekli görülen düzeltmeler yapılmıştır. Geliştirilen bu ders planı üç ders
saati boyunca uygulanmıştır. Ders planının uygulanması sırasında öğrencilere
konu ile ilgili çeşitli videolar, animasyonlar izletilmiş ve öğrencilerin
konuyu farklı yönlerden ele alabilecekleri çeşitli etkinlikler yapılmıştır. Bu
araştırmada, öğrencilerin farkındalıklarını incelemek amacıyla araştırmacılar
tarafından geliştirilen ve dört sorudan oluşan görüşme soruları, uygulama
öncesi ve sonrası uygulanmıştır ve öğrencilerin görüşlerindeki değişimler
incelenmiştir. Bunun yanı sıra, öğrencilerin görüşlerini derinlemesine
incelemek amacıyla yarı-yapılandırılmış görüşmeler gerçekleştirilmiştir. Elde
edilen bulgular; uygulama öncesinde, zirai gübre ve organik gübre kullanımını
destekleyen öğrenciler olduğunu göstermektedir. Bu öğrencilerin organik gübreleri
tercih etmesinde doğallık, fayda, çevreye ve canlılara zararsız olma gibi
faktörler etkili iken zirai gübre kullanımını ise ekonomik olmasından ve
ürünlerin güzel görünmesinden dolayı tercih ettikleri görülmüştür. Uygulama
sonrası, öğrencilerin tamamının görüşlerini organik gübre kullanıma yönelik
değiştirdiği ve görüşlerini daha detaylandırdığı bulgusuna ulaşılmıştır.
Fluoride Exposure in Early Life as the Possible Root Cause of Disease In Later Life
Authors: Nakamoto Tetsuo , Rawls H Ralph
Published: May 2018

Fluoride, one of the most celebrated ingredients for the prevention of dental caries in the 20th century, has also been controversial for its use in dentifrices and other applications. In the current review, we have concentrated primarily on early-life exposure to fluoride and how it may affect the various organs. The most recent controversial aspects of fluoride are related to toxicity of the developing brain and how it may possibly result in the decrease of intelligence quotient (IQ), autism, and calcification of the pineal gland. In addition, it has been reported to have possible effects on bone and thyroid glands. If nutritional stress is applied during a critical period of growth and development, the organ(s) and/or body will never recover once they pass through the critical period. For example, if animals are force-fed during experiments, they will simply get fat but never reach the normal size. Although early-life fluoride exposure causing fluorosis is well reported in the literature, the dental profession considers it primarily as an esthetic rather than a serious systemic problem. In the current review, we wanted to raise the possibility of future disease as a result of early-life exposure to fluoride. It is not currently known how fluoride will become a cause of future disease. Studies of other nutritional factors have shown that the effects of early nutritional stress are a cause of disease in later life.
Effect of Probiotic Lactobacillus reuteri on Salivary Cariogenic Bacterial Counts among Groups of Preschool Children in Jeddah, Saudi Arabia: A Randomized Clinical Trial
Authors: Alamoudi Najlaa M , Almabadi Eman S , El Ashiry Eman A , El Derwi Douaa A
Published: May 2018

Objectives: To evaluate the effect of probiotic Lactobacilli reuteri lozenges on caries-associated salivary bacterial counts (Mutans streptococci and Lactobacillus), dental plaque accumulation, and salivary buffer capacity in a group of preschool children. Study Design: The study group consisted of 178 healthy children (aged 3–6 years). Children were randomly grouped: the experimental group (n = 90) received L. reuteri probiotic lozenges and the control group (n = 88) received placebo lozenges, twice daily, for 28 days. Salivary Mutans streptococci and Lactobacillus counts, and buffer capacity were assessed using chair-side caries-risk test (CRT®) kits. The Simplified Oral Hygiene index (OHI-S) was used to assess dental plaque accumulation at baseline and after 28 days. Results: After 28 days, the experimental group had a statistically significant reduction in Mutans streptococci and lactobacilli (p = 0.000 and p = 0.020, respectively) and both groups had less plaque accumulation than at baseline. While the buffer capacity in the experimental group increased more than in the control group, it was not statistically significant (p = 0.577). Compliance was 90%, with no adverse events. Conclusions: Consumption of probiotic lozenges containing L. reuteri reduces caries-associated bacterial counts significantly. Probiotics consumption may have a beneficial caries-preventive effect.
Randomized Controlled Trial of Pulpotomy in Primary Molars using MTA and Formocresol Compared to 3Mixtatin: A Novel Biomaterial
Authors: Jamali Zahra , Alavi Vajiheh , Najafpour Ebrahim , Aminabadi Naser Asl , Shirazi Sajjad
Published: May 2018

Objective: This study was conducted to compare the efficacy of 3Mixtatin (a combination of simvastatin and 3Mix antibiotic) with MTA and Formocresol for the pulpotomy of primary molars. Study design: 114 children aged 3–6 years old with 150 primary molars were randomly allocated to three groups. MTA, Formocresol or 3Mixtatin were used for Pulpotomies. Hard setting zinc oxide eugenol was used to cover these materials. The teeth were restored with amalgam. Blinded radiographic and clinical examinations were conducted at 6, 12 and 24 months after treatment for the presence of pain, tenderness to palpation and percussion, sinus tract, swelling, presence of internal or external root resorption, inter-radicular radiolucency, and periapical lesion. Results: 122 teeth were available for 24-month follow-up study. The overall success rate was 78.9% for FC, 90.5% for 3Mixtatin and 88.1% for MTA group. There was no significant difference in overall success rate among the groups after 24-month follow-up (X2=2.43, df = 2, P =0.27). Conclusion: Our findings demonstrated remarkable results of 3Mixtatin in pulpotomy of primary teeth at the 24-month follow-up. Therefore, 3Mixtatin may be considered as an effective material in pulpotomy of primary teeth because of its successful results.
Tissue Engineering of Necrotic Dental Pulp of Immature Teeth with Apical Periodontitis in Dogs: Radiographic and Histological Evaluation
Authors: El Ashiry Eman A , Alamoudi Najlaa M , El Ashiry Mahmoud K , Bastawy Hagar A , El Derwi Douaa A , Atta Hazem M
Published: May 2018

Aim: To evaluate tissue engineering technology to regenerate pulp-dentin like tissues in pulp canals of immature necrotic permanent teeth with apical periodontitis in dogs. Study design: The study was performed on 36 teeth in 12 dogs. The experiment was carried out using split mouth design. In each dog 3 teeth were selected for implementing the study procedure. Apical periodontitis was induced in Group A and B teeth. Group (A): immature upper left 2nd permanent incisors that were transplanted with a construct of autologous dental pulp stem cells with growth factors seeded in a chitosn hydrogel scaffold. Group (B): immature upper right 2nd permanent incisor that received only growth factors with scaffold. A third tooth in each dog was selected randomly for isolation of dental pulp stem cells (DPSCs). Both groups were closed with a double coronal seal of white MTA (Mineral trioxide aggregate) and glass ionomer cement. Both groups were monitored radiographically for 4 months and histologically after sacrificing the animals. Results: There was no statistically significant difference in radiographic findings between group (A) and group (B) for healing of radiolucencies, while there was statistically significant difference between group (A) and group (B) regarding radicular thickening, root lengthening and apical closure. Histologically, group (A) teeth showed regeneration of pulp- dentin like tissue while group (B) teeth did not show any tissue regeneration. Conclusion: Dental pulp stem cells and growth factors incorporated in chitosan hydrogel are able to regenerate pulp- dentine like tissue and help in complete root maturation of non-vital immature permanent teeth with apical periodontitis in dogs.
El episodio de la cueva de Montesinos: hacia la cordura
Authors: Bobes Naves Carmen
Published: May 2018

La aventura de la Cueva de Montesinos (capítulos XXII y XXIII de la segunda parte de El Quijote y alusiones en otros capítulos) relata la anécdota de la bajada del Caballero a la cueva, donde permanece, según sus acompañantes, media hora, y según él, tres días, en los que vive una realidad paralela de romances, encantamientos y fantasías.          El análisis semiótico relaciona este episodio con otros: el de Sansón Carrasco, el del Caballero del Verde Gabán, el encantamiento de Dulcinea, y muestra que, bajo anécdotas diversas, todos plantean temas sobre la posibilidad del conocimiento: la realidad, los sentidos, la palabra, la verdad, el engaño, etc.          Las discordancias del tiempo dentro y fuera de la cueva remueven la consciencia de don Quijote e inician su vuelta a la cordura que desenlazará la novela cervantina.
Mágica fecha de Manuel Andújar, el fino hilo de unión entre distopía y realismo
Authors: Benito Temprano Claudia Sofía
Published: May 2018

En el ciclo narrativo Lares y penares Manuel Andújar trató de explicar la naturaleza de la España contemporánea recurriendo a la historia reciente. La novela que le da fin, Mágica fecha, se sitúa en el futuro y no es una obrar realista ni testimonial. En este artículo se tratará de explicar por medio de un análisis genérico cómo habla la obra del contexto socio-político del autor andaluz, y por lo tanto de qué manera se inserta en el ciclo mentado.
The intertemporal relation between expected returns and conditional correlations between precious metals and the stock market
Authors: Sakemoto Ryuta
Published: May 2018

This study explores whether conditional correlations between precious metals and stock markets impact upon expected returns on precious metals. The empirical evidence presents that there is no significant trade–off between conditional correlations and expected returns, which means that high returns on precious metals are not related to a lack of diversification benefits. Interestingly, high absolute values of conditional correlations lead to increases in expected returns, suggesting that the unstable cross-asset market condition is associated with the expected returns. This impact is stronger on silver than on gold.
¿Cómo está valorada la modalidad de escolarización combinada en Asturias según los/las especialistas?
Authors: Campo Mon Marián Ángel , Castro Pañeda Pilar , Álvarez Martino Eva , Álvarez Hernández Marina
Published: May 2018

La modalidad de escolarización combinada comienza en Asturias en el 2005. El alumnado con necesidades educativas especiales acude a dos centros simultáneamente, específico donde recibe atención especializada, y ordinario, donde se trabaja la inclusión. El objetivo principal de esta investigación es analizar la percepción de los especialistas acerca de esta modalidad, conocer su opinión sobre las actitudes de los miembros de la comunidad educativa, los recursos y la metodología de trabajo y determinar si existen diferencias según las características del profesorado. Método: 346 participantes en el estudio respondieron a una escala para valorar la modalidad de escolarización combinada tipo Likert. Resultados: Los profesionales opinan que las actitudes hacia este tipo de alumnado son buenas, pero demandan la mejora de recursos (materiales adaptados y profesionales) y de formación y metodología de trabajo (incentivar al profesorado, grupos de trabajo multidisciplinares, cursos). Se observa que variables como especialidad del profesorado, tipo de centro y experiencia in huyen en sus opiniones. Conclusiones: Los especialistas consideran que el funcionamiento de la modalidad combinada se puede mejorar con medidas concretas. Los resultados de este estudio son importantes para favorecer la inclusión del alumnado con necesidades educativas especiales.
Conocimientos e intereses sobre hábitos alimentarios saludables y práctica de actividad física. Un estudio con población adolescente
Authors: Cuervo Tuero Cristina , Cachón Zagalaz Javier , Zagalaz Sánchez Maria Luisa , González de Mesa Carmen González
Published: May 2018

La nalidad de esta investigación ha sido comprobar si los conocimientos e intereses de los adolescentes por la alimentación pueden estar interrelacionados con la práctica deportiva extraescolar y otras variables personales y familiares. Se ha aplicado el bloque II del Test de Evaluación de Preferencias e Intenciones de Conductas Alimentarias –TEPICA- (Benarroch, Pérez, y Perales, 2011), que mide los factores que incluyen en el comportamiento alimentario. A éste se le han incluido ítems personales, familiares, de realización de práctica deportiva, y número de horas semanales de dicha actividad. Los participantes, n=540, son estudiantes en Institutos Públicos de Educación Secundaria Obligatoria (ESO) y Bachillerato de una ciudad del Norte de España. Primeramente se realizó un análisis factorial exploratorio (AFE) para la validación y adaptación del test. A continuación, utilizando los factores obtenidos, se realizaron Análisis de varianza (ANOVA), Multivariado de varianza (MANOVA), correlación bivariada (Coe ciente de correlación de Pearson) y tamaño del efecto (de Cohen)...
El uso de los errores como herramienta del aprendizaje autorregulado en estudiantes de secundaria
Authors: Zamora Menéndez Ángela , Suárez Riveiro José Manuel , Ardura Diego
Published: May 2018

Este estudio tuvo como objetivo investigar las relaciones entre la facilidad con que los estudiantes de ciencias de secundaria detectan sus errores, su precisión en la autoevaluación y las variables motivacionales y cognitivas implicadas en el proceso de autorregulación. Tanto en la variable de detección de errores como la de autoevaluación se estudió el efecto de la utilización de guiones de evaluación. En la investigación participaron un total de 151 estudiantes de secundaria. Las variables cognitivas y motivacionales se midieron empleando el cuestionario MSLQ. Los resultados indican que no existe una relación directa entre los procesos de autoevaluación y los de detección de errores. Durante estos últimos se invocan más estrategias cognitivo-motivacionales que en los primeros. El uso de los guiones de auto-evaluación mejora ambos procesos.
Estudio neuropsicológico de la funcionalidad visual, las estrategias de aprendizaje y la ansiedad en el rendimiento académico
Authors: Martínez-Álvarez Isabel , Lajo Muñoz Alicia
Published: May 2018

En el contexto educativo actual, los aspectos neurosicológicos cobran gran importancia dada su repercusión en el rendimiento académico. Partiendo de esta premisa, el objetivo de esta investigación es el estudio de la relación entre los movimientos oculares sacádicos, las estrategias de aprendizaje y el nivel de ansiedad, así como su in uencia sobre el rendimiento en Lengua. La muestra estaba formada por 69 alumnos de 12-15 años, agrupados en función de su rendimiento. Se trata de un estudio no experimental, descriptivo, de tipo correlacional y comparación de grupos. Por un lado, se ha encontrado una relación inversa entre la lentitud en la lectura (prueba de movimientos sacádicos de King-Devick (1976)) y las estrategias de apoyo al aprendizaje medidas con la Escala ACRA (Román y Gallego, 2008) y entre las estrategias de apoyo y el nivel de ansiedad-estado, medida con el STAIC (Spielberger, Gorsuch y Lushene, 1970). Por otro lado, los alumnos con un rendimiento elevado presentan niveles inferiores de ansiedad-rasgo...
A study on comparison of short term three dose antibiotic prophylaxis with conventional prolonged postoperative antibiotic coverage in development of surgical site infections
Authors: Konidala M. V. Saila Suman , Gopalam Padmaja Rani , Kandati Jithendra
Published: May 2018

Background: Surgical site infections are still an increasing threat to the surgeons despite advances in techniques of surgery, patient care and sterilization practices. Most of the studies state that pre-operative antibiotic prophylaxis is effective in reducing the risk of wound infection in surgical procedures and has been a standard practice followed in many surgeries. Prolonged administration of prophylactic antibiotic has been associated with development of resistant bacterial strains and predisposes the patient in development of wound infection. The aim of the present study is to study the effectiveness of short term antibiotic coverage during decisive period in prevention of post-operative infection in surgical procedures.Methods: A prospective randomized and comparative study was done for one year with 100 cases divided into two groups A and B. Group A received prophylactic Ceftriaxone three doses intravenously, 12 h before surgery 1st dose, 1h before surgery 2nd dose and third 10h after surgery. Group B received Ceftriaxone twice daily for 5 days after surgery. The two groups were compared for development of SSI and associated risk factors.Results: The mean age of the total study group was 37.11± 12.12 years with 60% of males and 40% females. Overall incidence of SSI in study was 24% with Group A 10% and 14% in group B. Anemia, associated drain, increased BMI and undernourishment was associated risk factors and a statistically significant association was found with these risk factors in present study. Pseudomonas and Methicillin resistant staphylococcus aureus were the isolates in the study.Conclusions: Present study strongly recommends the use of antibiotics during surgery than administration after surgery. More care and proper management of the cases are required with associated risk factors like increased BMI, presence of drain and low Hb%. Large multicentric studies are further required to establish further associated risk factors and to identify the local pathogens and their resistance pattern. Appropriate use of antibiotics can substantially reduce the emergence of resistant pathogens and limit the cost of treatment.
A randomised prospective comparative study of evaluation of dexmedetomidine an adjuvant to ropivacaine for ultrasound guided supraclavicular block
Authors: Murthy V. S. S. N. , Hari Kiran Verma N. , Acharya Anand
Published: May 2018

Background: There are clinical evidences for efficacy of dexmedetomidine as an adjuvant to local anaesthetic for peripheral nerve block, but very few published study are available on continuation of dexmedetomidine, with ropivacaine for ultrasound guided supraclavicular block. The present study has been designed to elucidate the effect of dexmedetomidine, in combination ropivacaine on various parameters.

Methods: During period of 2 year and 3 months 84 patients were enrolled for this study. Patient in Group A were received 15 ml of 0.5% ropivacaine with 100 microgram one ml dexmedetomidine and Group B were received 15ml of 0.5% of ropivacaine with 1 ml of normal saline. Drug solution was prepared by same individual and was not part of study.

Results: Both the group were comparable to each other regarding demography profile. The duration of sensory block 644.96±72.4 min in group A and the duration of sensory block in Group B was 731.53±131.54 min with p value 0.00354. The duration of motor block was 661.5±29.25 in group A and 559.77±29.25 in Group B with P value 0.0001. Duration of analgesia in Group A was 457.06±34.47 min and it was 345.70±38.032 min in Group B. The supplementation of intravenous opioid was required in 3 patients in Group A and 10 patients in group B with P value 0.037.

Conclusions: When 100 microgram of dexmedetomidine was added as an adjuvant to ropivacaine is associated with early onset of sensory and motor block, prolongation of sensory and motor block and duration of analgesia in comparison with ropivacaine alone.
A study on clinical, immunophenotypic pattern in pediatric acute leukemias in a teaching hospital
Authors: Pandian Guna , Sankarasubramaian Murugesa Lakshmanan
Published: May 2018

Background: Acute leukemia contributes to nearly one third of the pediatric malignancies. For effective management of a curable malignancy, the epidemiology of childhood leukemias and audit of previously treated patients would be required. The objective was to study the clinical and immunophenotypic pattern of acute leukemia in children <12 years of age admitted in a tertiary centre.   Methods: Prospective study done on 31 children, diagnosed as leukemia and treated over a period of 3 years in GRH, Madurai. Detailed history analysis, clinical examination, lab investigations including flowcytometry were done.Results: ALL was the most common acute leukemia in children (90.3%). 85.7% were identified as B-cell and 14.3% as T-cell. Of the B-ALL, 87.5% was pre-B, 8.3% pro-B and 4.2% mature B ALL. Myeloid antigen co-expression was seen in 35.7%.  Fever was the most common symptom (87%) and hepatosplenomegaly was the most common sign (>90%). Poor outcome was noted in 42.3%. T-cell appeared to have worse prognosis than B-cell but did not retain independent prognostic significance in univariate analysis.Conclusions: B-ALL was more common than T-ALL. Extra medullary organ involvement indicates increased tumor burden and poor outcome. None of the clinical or laboratory parameters appeared to predict poor outcomes in our study and this may be due to small sample size. This study provides an insight into the data regarding the epidemiology, clinicopathologic feature and outcome of acute leukemia in a center with low resource settings.
Bacteriological profile and antibiotic resistance in cases of chronic otitis media and its clinical implications
Authors: Mallick Ajay , Sharma Harikesh , Mishra Awadhesh K. , Maggon Nidhi V. , Sethi Ashwani
Published: May 2018

Background: Chronic otitis media (COM) is the commonest otologic conditions worldwide with great risk of irreversible complications. Early bacteriological diagnosis is essential for appropriate effective therapy to reduce the disease burden. However in our clinical practice, it was noticed that the morbidity of the disease was mostly non responsive to standard antibiotic medical care. The poor response to routine treatment gave rise to suspicion of antibiotic resistance. This prompted us to undertake this study with the objective to isolate and identify the causative organisms in COM in our clientele and study their antimicrobial susceptibility pattern for a better analysis and institution of accurate therapy.

Methods: A prospective cross sectional analysis was performed using culture and antibiotic susceptibility test results of 500 patients who visited the ENT OPD at a tertiary care centre between July 2016 to June 2017.  

Results: A positive culture was obtained in 466/500 (93.2%) of the samples. No growth was seen in 34 patients (6.8%). 454 samples showed single bacterium while 12 samples had mixed growth. Pseudomonas aeruginosa was the predominant organism (54%) followed by Staphylococcus aureus. On antibiotic sensitivity, high resistance patterns to most common first line antibiotics used in COM was observed.

Conclusions: Irrational use of antibiotics for management of COM has led to the emergence of multidrug-resistant bacterial strains. Evaluation of micro bacterial growth and their antibiotic sensitivity pattern in local area helps in prescribing empirical antibiotics for successful treatment of COM.

 

 