bluuebunny/crossref_metadata_2025 huggingface dataset:
Decoding vestibular migraine for easier diagnosis
Authors: Vazhipokkil Anoop C. , Shenoy Ashwini
Published: April 2019

Background: Due to the absence of a unified set of diagnostic criteria, vestibular migraine is always an underdiagnosed entity. This study was undertaken to find specific pointers in the diagnostic protocol which can help in diagnosing vestibular migraine and also to assess our treatment module for vestibular migraine.

Methods: An elaborate proforma was prepared for evaluating each patient at our vertigo clinic for a time period of two years. A detailed history is followed by general examination, ENT examination, specific tests for eyes, tests for vestibulospinal tract, and also a few more tests such as Doppler, pure tone audiogram, ECHO etc. when the diagnosis was in doubt. A total of 206 patients were evaluated. Vestibular migraine cases were started on our drug regimen of Tab flunarizine once daily and subjected two follow ups (at 4 weeks and 12 weeks).  

Results: Total of 20 patients (9.7%) diagnosed as vestibular migraine. There was a slight preponderance to female population. A positive history of recurrent headache and neck pain were definitive clinchers in diagnosing vestibular migraine. All 20 patients had alleviation of symptoms with regards to severity and frequency of episodes.

Conclusions: Detailed history and elaborate vestibular examination alone is necessary for diagnosing vestibular migraine. Flunarizine regimen for a period of 3 months is found to be effective in relieving the symptoms. Adjuvant vestibular rehabilitation exercises mandatory for total alleviation of symptoms.
CT scan vs nasal endoscopy findings in the diagnosis of chronic rhinosinusitis: our experience
Authors: Baruah Shruti , Vyas Pratibha , Srivastava Arpit
Published: April 2019

Background: Diagnostic nasal endoscopy and CT imaging are both widely used essential diagnostic tools for chronic rhinosinusitis (CRS). This study analyses their individual roles in the management of CRS as well as the degree of correlation between the two.

Methods: A prospective observational comparative study was conducted in the Department of Otorhinolaryngology, Mahatma Gandhi Hospital, Jaipur from January, 2017 to June, 2018 on a sample size of 201 patients diagnosed with chronic rhinosinusitis, as per AAOHNS guidelines. DNE and CT PNS were done for all patients enrolled in the study, the findings of each were correlated and their individual sensitivity and specificity for each variable was calculated.  

Results: On Comparing CT findings with diagnostic nasal endoscopic findings, Polyps were seen in 91 patients’ CT scans as opposed to 124 on DNE. B/L Polyps on CT imaging vs bilateral ethmoidal polyps visualized during DNE revealed a highly significant “P” value; whereas for antrochoanal polyps or unilateral polyps there was no significant difference. Maxillary sinus involvement is the most commonly observed finding in CT scan of PNS in CRS while deviated nasal septum is the most common finding on a diagnostic nasal endoscopy, seen in 60.7%. For anatomical variants like concha bullosa and paradoxical middle turbinate, no significant difference was seen.

Conclusions: CT scans and DNE are both key pre-operative diagnostic tools for patients of CRS and both are complementary to each other in detecting type and extent of pathology.
DCP vs LCDCP in forearm fractures: a comparative study of functional outcomes
Authors: D’souza Aaron R. , Krishna Vamsi M. , Eswaran Kaushik S. , Kumar Shailesh
Published: April 2019

Background: Forearm fractures in general, and diaphyseal fractures in specific, are one of the most common fractures which accounts for about 31% of upper limb fractures seen in emergency. Early reduction and fixation is necessary in order to restore the function of forearm so as to be able to carry out their daily activities. The objective of this study was to compare the functional outcomes of forearm fractures fixed with DCP and LC DCP.

Methods: The present study was a hospital based study, and a prospective, comparative study. A total of 40 patients with fracture of both bones forearm were taken up for the study, and randomly divided into 2 groups of 20 patients each. They were followed up for a period of 1 year.

Results: The majority of patients were males (31 males and 9 females), involving age group 21-30. The left side was more common than right in both groups. The site of fracture was middle one-third of forearm in both groups (60% in group A and 65% in group B). The time for union was on average 4 weeks for LC DCP and DCP. ROM was full in 85% in DCP group and 90% in LC DCP group. Overall results were comparable in both groups. Excellent in 34 cases (18 in LC DCP, 16 in DCP), satisfactory in 5 cases (2 in LC DCP, 3 in DCP) and unsatisfactory in one case treated with DCP.

Conclusions: LC DCP provides slightly better functional outcome in terms of time taken for union, early mobilisation and range of motion. However, it is more expensive than DCP.

 

 
Quality of life in patients with acne vulgaris in a tertiary care centre: a cross sectional study
Authors: Eram Hafsa , Shetty Vinma H. , Goel Saumya , Babu Amita Murali
Published: April 2019

Background: Acne vulgaris is a chronic inflammatory disease of pilosebaceous units which has great psychological impact and causes depression, anxiety, and low self-esteem.

Methods: It was a hospital-based, cross-sectional, prestructured, questionnaire-based study done in 120 individuals in the age group 12-30 years using two specific HRQoL indices-Cardiff Acne Disability Index (CADI) and Acne-speciﬁc Quality of Life (Acne-QOL) to understand the impact of acne on the quality of life.

Results: Male to female ratio was 2:3. The mean age was 19.23±1.7. The mean CADI score was 5.3. Majority of the patients had grade 2 acne. Based on the CADI questionnaire, the number of males (61.7%) and females (60.2%) was maximum in the medium score. Grade 1 acne had maximum number of patients showing low score followed by grade 2 acne. Based on the acne-QoL questionnaire, maximum patients were in the 11-20 score range, followed by the 21-30 score range.

Conclusions: Acne is not only a cosmetic problem, but also has significant psychological impact. Hence, impact of acne on QoL must be considered in the management of facial acne.
Twenty nail dystrophy with alopecia areata in an atopic child
Authors: Divya G. , Thomas Jayakar
Published: April 2019

Twenty nail dystrophy mainly describes roughness of nail which can be idiopathic or it could be associated with various other dermatological conditions like psoriasis, alopecia areata and eczema. Here we report a case of twenty nail dystrophy with alopecia areata of scalp in a 6-year-old child.
Créditos de carbono da bovinocultura brasileira por modelo quantitativo e parcimonioso
Authors: Sá Neto José Abrantes de , Vieira Allan Sarmento , Silva Érika Lira da , Fernandes Francisco Dinarte De Sousa
Published: April 2019

O objetivo desta pesquisa é mensurar os créditos de carbono (CO2) da atividade bovinocultura brasileira utilizando um modelo parcimonioso, que tem como base projetos de desenvolvimento limpo (biodigestores) que levem em consideração as peculiaridades climáticas de uma determinada região do Brasil. Com o modelo matemático escolhido, foi feita uma simulação, por intermédio de cenários idealizados, comparando com a metodologia proposta pelas Nações Unidas (ONU), a fim de averiguar a sua eficaz numérica. Em seguida foram selecionados dois Estados de diferentes regiões brasileiras, com intuito de validar a metodologia proposta. Os resultados mostraram que o modelo escolhido é um algoritmo preciso e parcimonioso capaz de gerar informações confiáveis que consideraram as peculiaridades de uma determinada região (pressão atmosférica, quantidade de dejetos e temperatura), já que as mesmas influenciam no processo de produção do biogás.
Perfil socioeconômico e percepção ambiental dos moradores do entorno da Lagoa do Apodi, Rio Grande do Norte
Authors: Soares Lorena Lívina Lima Oliveira , Pinto Filho Jorge Luis de Oliveira , Feitosa Alex Pinheiro , Bezerra Joel Medeiros
Published: April 2019

Este trabalho tem por objetivo descrever o perfil socioeconômico dos moradores do entorno da Lagoa do Apodi, Rio Grande do Norte, apontando a percepção ambiental destes atores locais. Como procedimento metodológico foi utilizado um questionário semiestruturado com questões sobre o perfil socioeconômico do entrevistado e sua percepção ambiental. Foram realizadas 185 entrevistas, durante os meses de fevereiro a maio de 2017. Constatou-se que os moradores questionados em sua maioria são naturais de Apodi que residem há mais de 20 anos nessa área, apresentando baixo nível de escolaridade, com ocupações informais e, de rendimentos financeiros de até 1 salário mínimo por mês para maioria. Evidenciou-se que a maioria da população local apresenta um vínculo afetivo com a lagoa, já que consideram um ambiente natural para ser preservado e apreciado. Observou-se que este ambiente apresentou diversos usos ao longo dos anos, com fortes laços para atividades tradicionais (agricultura e pesca) e abastecimento de água para consumo humano no passado e, o surgimento do uso com fins recreativo no presente, mediante a construção do calçadão da lagoa. Apurou-se que os moradores consideram que a lagoa se encontra poluída, sendo a poluição urbana a principal fonte de alteração no decorrer dos anos. Para tanto, faz se necessário à realização de programas de educação ambiental e sanitária que busquem a valorização de ambientes aquáticos.
Morfometria de sementes leguminosas produzidas em diferentes espaçamentos
Authors: Monteiro Shirley Santos , Marini Fillipe Silveira , Santos Dualyson Da Silva , Pereira Emmanuel Moreira , Vasconcellos Andreia
Published: April 2019

A produção de sementes de leguminosa pode ser uma estratégia para aumentar a renda dos agricultores familiares, assim como a melhoria das características do solo. O objetivo deste trabalho foi avaliar as características morfométricas das sementes de espécies leguminosas produzidas em diferentes espaçamentos. O experimento foi conduzido na Universidade Federal da Paraíba, Campus III, Bananeiras, Paraíba. O delineamento utilizado foi em blocos casualizados no esquema fatorial 3 x 3, sendo três espécies de leguminosas (mucuna preta, feijão de porco e lablab,) e três espaçamentos (0,50 x 0,50; 0,50 x 0,75 e 0,50 x 1,0 m) com três repetições. Avaliou-se as características físicas: comprimento e largura de vagem, comprimento e largura de semente, peso da vagem com semente, peso da vagem sem semente, peso da semente, número de semente por vagem, produtividade, peso total da vagem, peso total da semente e peso de 100 semente. A leguminosa Feijão de Porco teve maior acréscimo no desempenho morfométrico, seguido da Mucuna Preta e Lablab. Os espaçamentos não apresentaram influência na morfometria das sementes das leguminosas.
The Emerging Role of Succinate Dehyrogenase Genes (SDHx) in Tumorigenesis
Authors: Nazar Elham , Khatami Fatemeh , Saffar Hiva , Tavangar Seyed Mohammad
Published: April 2019

Transformation of a normal cell to cancerous one is dependent on the accumulation of several genetic and epigenetic alterations. One of the candidate driver genetic alterations can happen in succinate dehydrogenases (SDHx) coding gene include SDHA, SDHB, SDHC, SDHD, and SDHAF2.  The most important SDH mutation is in the SDHD gene, which encodes the smallest subunit of mitochondrial complex II (SDH). It has key function both in familial and non-familial hereditary paraganglioma/phaeochromocytoma syndrome (HPGL/PCC). SDHx genes mutations can have resulted in genetic and epigenetic changes like histone hypermethylation. These properties can lead to succinate-mediated inhibition of α-ketoglutarate-dependent dioxygenases. So hypoxic conditions can generate subsequent neoplastic transformation, and in this review, we are presenting the role of SDHx in several malignancies.
Determining Model for Maximum Blood Request (MSBOS) for Surgery: An Elective Surgery in Imam Ali Hospital, Zahedan, Iran
Authors: Hashemi Seyed Mehdi , Soleimanzadeh Mousavi Seyed Hossein , Tavakolikia Zeinab
Published: April 2019

Background: Nowadays, excessive blood intake is one of the most common problems in educational hospitals, causing issues such as the lack of proper distribution of blood products among centres, increases in costs and blood bank workloads. So, programs such as a Maximum Surgical Blood Ordering Schedule (MSBOS) were introduced to design a blood ordering schedule, which is a guide to normal transfusion needs for common surgical procedures. 
Materials and Methods: This study was a descriptive cross-sectional study. The sampling method was designed and distributed among all sectors of the hospital. Each sector according to the demand for blood and cross-matched transfused units entered the rate of wasted and unused blood bags on the related forms. This study was performed on 1568 patients, of whom 562 (35/84%) were given blood transfusions.
Results: The aim of this study was to determine the pattern for the maximum surgical blood order schedule (MSBOS) for elective surgical procedures/in elective surgery cases in Imam Ali Hospital, Zahedan. This study was performed on 1568 patients, of whom 562 (35/84%) were given blood transfusions. The mean C/T ratio was 1.61 ± 0.99, the mean TI was 0.61 ± 0.38, and the mean T index was 36.4 ± 30.16%.
Conclusion: In general, only 55% of the blood units were used. Hernia surgery, thyroidectomy, and patients with renal problems had the greatest number of wasted units. Therefore, according to the results, indications of blood donation should be made correctly by health care personnel in all patients requiring a blood transfusion, and if there is an increased number of indications, packed cells are requested.
Poultry: A receptacle for non-typhoidal Salmonellae and antimicrobial resistance
Authors: Bangera Sohan Rodney , Umakanth Shashikiran , Chowdhury Goutam , Narayan Saha Rudra , Mukhopadhyay Asish K. , Ballal Mamatha
Published: April 2019

Background and Objectives: Non-typhoidal Salmonellosis, a zoonotic infection associated with acute gastroenteritis is caused by non-typhoidal salmonellae (NTS). The study was carried out to determine the prevalence of NTS serovars and their antimicrobial resistance along with the presence of the virulence gene (invA gene)  in poultry samples.
Materials and Methods: This is a prospective cross-sectional study carried out at the Enteric Diseases Division, Kasturba Medical College, Manipal, South India from January 2016– December 2017. Poultry samples were collected randomly from two local poultry farms in Udupi district and processed following CDC standard protocol.
Results: From the 396 poultry meat samples, intestinal contents and faecal samples collected, 58 NTS serovars were isolated showing a prevalence of 14.64%. Salmonella Infantis, 43.1%, 25/58 was the commonest serovar. Resistance to ciprofloxacin
72.41%, ampicillin 32.8%, gentamicin 17.24%, cotrimoxazole 29.31% and amoxicillin-clavulanic acid 6.9% was observed.
The invA gene was detected in 43 NTS isolates (74.13%).
Conclusion: Poultry sources are recognized as a significant cause for non-typhoidal salmonellosis. Therefore, hygienic measures should be initiated to reduce the contamination of meat and poultry products with virulent strains of Salmonella that are of public health significance.
The frequency of Epstein-Barr virus among hemodialysis patients, Ahvaz, Iran
Authors: Nahid Samiei Rahil Nahid , Mahmoudvand Shahab , Shokri Somayeh , Makvandi Manoochehr , Shahbazian Heshmatol- lah , Pirmoradi Roya , Shayanpur Shokouh , Makvandi Kimia , Nowrozi Sepideh
Published: April 2019

Background and Objectives: Epstein-Barr virus (EBV) has infected more than 90% of adults worldwide. EBV infection is asymptomatic in healthy individuals and is controlled by a robust immune response while in individuals with weakened immunesystems including Hemodialysis (HD) patients and transplant recipients leads to serious illnesses. This study was aimed to investigate the frequency of EBV among the HD patients.
Materials and Methods: The cross-sectional study was carried out on 84 HD patients. These sera were checked for an- ti-EBV (VCA) IgG Ab assessment using enzyme-linked immunosorbent assay (ELISA). The DNA was extracted from the sera samples and tested for EBV DNA using nested PCR.
Results: 52/84 (61.9%) of HD were males and 32/84 (38.1%) were females. The average age of participants was varying from 18 to 85 years while the mean age was 52 ± 1.57 SD years. 81 of 84 (96.42%); including 49/52 (94.23%) male and
32/32 (100%) female, were positive for anti-EBV (VCA) IgG antibody while 3 (3.58%) were negative. No significant dif- ferences were observed between the subjects regarding gender (P=0.28). EBV DNA was detected in 7 (8.33%) individuals, including 6 (11.53%) and 1 (3.12%) in male and female, respectively (P=0.24).
Conclusion: Our study results showed that high prevalence of anti-EBV (VCA) IgG antibody (96.42%) were observed among the HD patients. Although the status of EBV latency was not performed, but it seems many of these patients are at risk of EBV-reactivation during the organ transplantation. As a result, it is recommended that the detection of EBNA-1 gene as a marker of EBV latency should be implemented for all HD patients to prevent EBV reactivation during organ transplantation.
Tolerance mechanisms of Indonesian plant varieties of yardlong beans (Vigna unguiculata sub sp. sesquipedalis) against drought stress
Authors: Lestari M. W. , Farita N. , Sharma A. , Purkait B.
Published: April 2019

Plants that experience drought stress protects themselves through several mechanisms namely avoidance, tolerance, recovery, and escape. Eight varieties of yardlong bean plants were subjected to a drought stress at the rates of 50% of the
field capacity (FC) and 100% of the field capacity (FC). The results showed that yardlong bean plants possessed the mechanisms of escape, demonstrated by the increase in Peroxidase (POX) enzyme activity. Avoidance was demonstrated by the reduced
evapotranspiration surface of the decreased leaf surface area, and the increased number of closed stomata. Tolerance was demonstrated by the increased proline accumulation.
Changes in growth, biochemical components and antioxidant genes expression in rice seedling (Oryza sativa L.) cultivar ‘IR64’ under salt stress
Authors: Pharmawati M. , Wijaya I.M.A.S.
Published: April 2019

One of abiotic stresses that affects rice growth is salinity. Plant must develop adaptation process which includes morphological, biochemical and molecular changes. This research aimed to evaluate morpho-biochemical and molecular responses of
rice ‘IR64’ to several levels of salinity stress at seedling stage. Seedlings of ‘IR64’ were grown in a hydroponic system and treated with different levels of salinity stress (4dSm-1, 6dSm-1, and 12dSm-1) for seven days. Responses were recorded on
the final day of salt treatments. Gene expression analyses were done by semi-quantitative RT-PCR. RNA was extracted using RNase plant mini kit (Qiagen) and cDNA was synthesized using GoSript™ Reverse Transcription System (Promega). Results showed
that shoot height and fresh weight decreased under salt stress. At plants treated with salt, the chlorophyll contents were lower than that of control plants, while MDA levels were higher in salt treated plants. Semi-quantitative PCR for MnSOD1and
cCu/ZnSOD1 revealed that MnSOD1 and cCu/ZnSOD1expressions increased under salt stress which indicated oxidative stress defence, with the highest expression at 4dSm-1and 6dSm-1 treatment, respectively.
Effect of culture media, plant growth regulators and genotypes on growth and developmental stages of oil palm (Elaeis guineensis Jacq.) zygotic embryos
Authors: Sparjanbabu D.S. , Kumar P. Naveen , Krishna M.S.R. , Ramajayam D. , Babu B. Kalyana , Susanthi B.
Published: April 2019

Oil palm (Elaeis guineensis Jacq.) has become the largest traded vegetable oil in the world due to its innumerable uses and its huge economic importance. Which increases the requirement of quality seedling but the conventional seed production
limits the commercial seed production with its long germination period and low germination rate. In this context in vitro germination of zygotic embryo could be a promising alternative. Hence in this study the effect of culturing media, plant growth
regulators and genotypes were assessed on in vitro regeneration and plantlet development of oil palm zygotic embryos. Zygotic embryos of four elite genotypes were cultured on MS, N6 and Y3 media, with or without plant growth regulators (NAA, BA and
GA3-0.2mg/lt). There was no effect of culture media, plant growth regulators and genotypes on germination of zygotic embryos. Whereas on the growth and development of in vitro plantlets, there was a significant effect of culture media and genotypes.
Where culture media N6 performs well and Y3 has shown more abnormality. In case of genotypes, genotypes G1 and G2 shown better performance when compared to genotypes G3 and G4. The effect of plant growth regulators on germination and plant growth was
non significant.
Effect of leaf nutrient content at various age groups of guava (Psidium guajava L.) on fruit yield and quality in semi- arid region of Rajasthan
Authors: Sharma Shweta , Kumawat B.L.
Published: April 2019

In order to evaluate effect of leaf nutrients content at flowering and harvesting stages on fruit yield and quality parameters of guava a study was conducted on the orchards found in Jaipur,Ajmer and Sawai Madhopur districts of Rajasthan.
According to this study all the leaf nutrients like nitrogen, phosphorus, potassium, iron, manganese, copper and zinc showed the positive correlationship with fruit quality parameters like total soluble solids, total sugars, total acidity, reducing
sugar, ascorbic acid, fruit weight and fruit yield. At different age groups like less than 5, 5 to 15 and more than 15 years plant showed different plant nutrient adsorption level because plant root is not able to adsorb nutrients at early age as
compare to middle age group plants like 5 to 15 years and at more than 15 years age plant is not much vigorous as young age group plants. To study effect of leaf nutrients at different age intervals like less than 5, 5 to 15 and more than 15 plant
showed different extent of effect as nutrient uptake ability differ with age. In this study, more than 15 years age group orchards were found deficient in nitrogen, phosphorus and zinc whereas potassium, iron and manganese content were in optimum
range at all the studied age groups. Maximum fruit yield was observed in 5 to 15 years age group orchards at Sawai Madhopur.
Studies on physical attributes and processing suitability of sapota cultivars
Authors: Bons Harsimrat K. , Rehal Jagbir
Published: April 2019

Sapota (Manilkara achras L.) is one of the major crops of India, commonly known as Chikoo and has good nutritional properties. The physical properties of two varieties of sapota viz. cricket ball and kallipati were determined to facilitate
the designing of grading machines. It was found that the average weight and values of length, breadth and thickness for cricket ball were 51.63g, 41.7mm, 46.2mm and 46.3mm whereas for kallipati they were 58.13g, 46.9 mm, 46.8 and 47.0mm respectively.
The TSS values for cricket ball was 26.25 and for kallipati 25.37°B and their respective acidity were 0.16% and 0.18%. Jam was prepared from two varieties of sapota viz. cricket ball and kallipati to determine their processing suitability. The
sensory evaluation of the samples revealed that the jam prepared from cricket ball variety obtained higher overall acceptability scores (7.86) on a 9 point hedonic scale owing to the higher values for appearance and taste. The B:C ratio for sapota
jam was found to be 1.87 showing its viability for processing the fruit into jam.
Productivity and soil moisture conservation studies of pigeon pea based intercropping systems as influenced by different land configurations
Authors: Garud H. S. , Asewar B. V. , Dhawan A. S. , Gokhale D. N. , Mirza I. A. B.
Published: April 2019

A field experiment was conducted to study effect of various land configurations on soil moisture conservation and productivity of pigeonpea at experimental farm of AICRP for dry land Agriculture, V.N.M.K.V., Parbhani during kharif season of
2015 and 2016. Soil of experimental field was medium deep black with low in organic carbon, low in available nitrogen, medium in available phosphorus and high in available potassium.The experiment was laid out in split plot design with three main
plot treatments and four sub plot treatments. The gross and net plot sizes are 7.2x5.4m2 and 5.4x3.6m2 respectively. The pigeonpea variety BDN-711 was used for sowing with spacing 90 x 20 cm. The main plot treatments were three land configurations as
(L1) broad bed furrow (BBF), (L2) ridges and furrow and (L3) flat bed method. Sub plot treatments were four intercropping systems i.e. (I1) pigeonpea + soybean (2:1), (I2) pigeonpea + green gram (2:1), (I3) pigeonpea + black gram (2:1) and (I4)
pigeonpea + cowpea (2:1). It was observed that seed yield of pigeon pea andpigeonpea equivalent yield were significantly affected due to different land configuration and intercropping systems. The highest pigeonpea seed yield (1588 kg ha-1) and
pigeonpea equivalent yield (1823 kg ha-1) were obtained with Broad bed furrows (L1) followed by ridges and furrow (L2). Among the intercropping systems, pigeonpea + greengram intercropping system (I2) recorded higher seed yield (1574 kg ha-1) and
pigeonpea equivalent yield(1832 kg ha-1).Periodical soil moisture observations in different land configuration considering depth of soil, higher average soil moisture was recorded under broad bed furrow followed by ridges and furrows while lesser was
recorded under flat bed sowing.
HUBUNGAN ANTARA BAURAN PEMASARAN DENGAN LOYALITAS PASIEN RAWAT JALAN DI RUMAH SAKIT DAERAH KALISAT KABUPATEN JEMBER TAHUN 2017
Authors: Hayati Yuliasfa Sirrul , Sandra Christyana , Herawati Yennike Tri
Published: April 2019

Marketing mix in hospital is ​​a group of controllable variables that can be used by hospitals to influence the reaction of service buyers. The marketing mix consisting of 7P (Product, Price, Place, Promotion, Process, Person, and Physical Evidence) can affect patient loyalty. This study aims to analyze the relationship between marketing mix and patient loyalty. The study method used is analytic with cross sectional design. The sample of study is 90 respondents using systematic random sampling technique. The result showed that most respondents rated the product mix (82%), the price mix (81%), the place mix (72%), the process mix (79%), the mix (84%), and the physical evidence mix (82% ) is good. However, most respondents rated promotion mix (92%) classified as less good. Based on the results, it is concluded that there is no significant relation between place mix and physical proof mix with patient loyalty, and there is significant relation between product mix, price mix, promotion mix, and process mix with patient loyalty. To increase loyalty patients can improve or maintain product mix, price mix, promotion mix, process mix, and people mix.
PENGARUH HOUSE INDEX DAN MAYA INDEX TERHADAP KEJADIAN DEMAM BERDARAH DENGUE DI KECAMATAN GROGOL KABUPATEN SUKOHARJO MENGGUNAKAN GEOGRAPHIC INFORMATION SYSTEM (GIS)
Authors: Maharani Nine Elissa , Rohsulina Pranichayudha
Published: April 2019

Dengue fever is an important public health problem in indonesia, in the year 2014 the number of death due to dengue fever in Indonesia 903 people from 99499 cases. Sukoharjo district is one of the bloody endemic distrric in central java. In eradicating dengue fever, the larva survey used is a visual method using the entomology indicator, the house index and maya index. This study aims to determine the effect of house index and maya index on the incidence of dengue fever in  Grogol district of Sukoharjo using geographic information system (GIS). The research method used is an analytical survey wuth cross sectional approach. The result of the study showed a maya index effect on the incidence of dengue fever in  Grogol district of Sukoharjo (p value 0,00), there is no effect of house index on the incidence of dengue fever in Grogol District of Sukoharjo (p value 0,87).
Occurrence of the Eastern Barn Owl Tyto alba delicatula in the Centennial Parklands, Sydney
Authors: Mo Matthew
Published: April 2019

The occurrence of owls in the urban environment has been of interest, with recent records of the Eastern Barn Owl Tyto alba delicatula in highly urbanised locations in Sydney, New South Wales. During the long-term monitoring of bird assemblages in the Centennial Parklands, Barn Owls were consistently found roosting under the crowns of Canary Island Date Palms Phoenix canariensis in six major time periods between 2013 and 2018. Atlas records show two earlier records of this species in the Parklands. Since December 2013, there have been some site visits in which 2–3 Barn Owls have been found roosting in the Parklands.
Active Power Tracking Control Strategy to Suppress DC-Link Voltage Rising with Enhanced Fault Ride-Through Capability using Superconducting Fault Current Limiter
Authors: Choi Sang-Jae , Lim Sung-Hun
Published: April 2019

Building a new power plant to address the growing demand for power due to population concentration in the metropolitan area is one of the world's major concerns. However, since a large power plant can not be located around the city due to burden of economic cost, building power plant outside metropolitan and cities is necessary. Therefore, new power generation facilities are promoting policies to provide distributed generator(DG) with a small capacity relatively near the metropolitan. When the DG (photovoltaic, wind farm, etc.) is connected with the grid using medium voltage direct current (MVDC) system, voltage sourced converter(VSC) should supply reactive power to the grid, because of fault ride through(FRT) operation in grid fault. If the voltage drop is severe, the converter should be disconnected from the grid immediately without supplying the reactive power, resulting in a considerable economic loss. In general, superconducting fault current limiter(SFCL) is introduced as a measure to enhance FRT capability. In this paper, we use trigger type SFCL which protects superconducting element and reduces low voltage. On the other hand, the active power unbalance of the DC-link and the DC voltage rise due to the reactive power supply of the grid-side converter. The rise of the DC voltage causes the P (active power), Q (reactive power) control of the converter to deviate, causing malfunction and damage of the DC equipment. Therefore, the rise of the DC voltage must be prevented. In this paper, we consider the suppression the DC voltage rising caused by the FRT operation through the active power tracking control (APTC).
Extract Mushroom (Volvariella volvaceae) As a Stimulator Increased Hemoglobin Animal Test
Authors: Muharram Andi Fatmawati , Naim Nurlia , S A Heri
Published: April 2019

This study aims to determine the ability of extracts of edible mushroom to increase hemoglobin rabbit. The method used is by using a photometer Cyanmethemoglobin C-206 Biochemyistri. Observations made with three times the measurement of hemoglobin, the measurement of the initial Hb, after induced, and after treatment. Extract of mushroom with a concentration of 2%, 4%, and 6% w/v to increase hemoglobin in test animals rabbits respectively 11.8%, 35.54%, and 79.32%. Extract with a concentration of 6% w/v had no significantly different effect with the provision of suspension ferosi sulfate 0.117% w/v, namely 86.9%. Analysis results obtained by the method ANAVA Fhitung > Ftabel at α = 0.05 and α = 0.01 with the value of each 275.52 > 275.52 3.48 and > 5.99, which means the results obtained that there are significant significant differences in the effects of each treatment.
Biodegradation Capability Analysis of Petroleum Hydrocarbon by Marine Bacteria Isolate From Territorial Water Column of Paotere Port Makassar as In Vitro
Authors: Mas'ud Asrianty
Published: April 2019

The research about the biodegradation capability analysis of petroleum hydrocarbon by marine bacteria isolate from territorial water column of Paotere port Makassar as in vitro was conducted. The aim of this research was to know the biodegradation capability of petroleum hydrocarbon quantitatively by marine bacteria isolate from water column in Paotere port, Makassar. This research consist of two phases of working, those are characteristic of hydrocarbon degraded bacteria and quantitative process of hydrocarbon biodegradable from degraded bacteria. The result shows there are three different isolates ; isolate A in bacilli shape (Gram negative), isolate B in coccus shape (Gram negative), and isolate C in coccus shape (Gram positive) and the capability to degrading hydrocarbon from the highest respectively are isolate B (83,91%), isolate A (80,53%), and isolate C (72,86%).
Analysis of Water Quality In Sebangau River Kereng Bengkiray Port Based On Phytoplanktons Diversity and Composition
Authors: Nirmalasari Ridha
Published: April 2019

This research is aimed to know the diversity, composition and structure of phytoplankton community and the contamination status of organic wastes in the Sebangau river bengkiray Palangkaraya port. This research uses purposive sampling that is calculation of dominance index calculation data for phytoplankton using Simpson dominance index formula. With a total composition for all types of 756 species. The results showed that the highest composition was Bacillaria group (79%), while the other group was Chlrophyta (9%) and Cyanophytacomposition (12%). The presence of phytoplankton as an indicator that the water in the waters of the Sebangau river is not polluted, because the phytoplankton is a plant whose respiration system utilizes carbon dioxide and releases oxygen so that the water in the waters of the Sebangau River is of good quality and feasible to consumed.
Quantificação de proteínas do sêmen de touros Guzerá e suas associações com características andrológicas Polimorfismos
Authors: Dias J.C. , Martins J.A.M. , Emerick L.L. , Andrade V.J. , Vale Filho V.R.
Published: April 2019

Avaliaram-se os perfis cromatográficos por gel filtração de proteínas do plasma seminal de 19 touros jovens Guzerá e suas associações com parâmetros andrológicos e testosterona. A concentração de proteínas totais no plasma seminal variou de 2,86 a 78,82 mg/ml, com média de 17,18 ± 20,49 mg/ml, com grande variabilidade entre os touros. Tais concentrações estão correlacionadas (p
El pastoreo restringido de avena y su frecuencia de asignación afecta el desempeño de terneros pastoreando campo natural
Authors: Cazzuli F. , De Barbieri I. , Jaurena M. , Silveira C. , Montossi F.
Published: April 2019

Las restricciones nutricionales de los terneros de recría sobre campo natural durante su primer invierno es un problema común en Uruguay, dada la insuficiente calidad y cantidad del forraje. La suplementación invernal del ganado de carne utilizando granos o sus subproductos y pastoreando sobre pasturas nativas, ha sido estudiada previamente, pero muy poca atención se le ha dado a el acceso restringido de animales a una base forrajera mejorada adyacente, como lo puede ser un verdeo de avena. Treinta y seis terneros machos castrados pastoreando sobre campo natural durante su primer invierno fueron asignados al azar a uno de los siguientes tratamientos: (a) Diario (D) con acceso a una parcela adyacente de avena por 4 horas al día (28 horas/semana); (b) de Lunes a Viernes (LaV) con acceso al mismo verdeo por 5 horas 36 minutos por día (28 horas/semana); (c) Testigo (T), en el que los animales no tenían acceso alguno al verdeo de avena. El experimento fue dividido en dos fases: la fase I en donde los tratamientos fueron aplicados (invierno) y la fase II, luego que los mismos fueran aplicados (primavera), a los efectos de evaluar un eventual arrastre de efectos. El acceso restringido a la avena afectó la disponibilidad y altura del forraje del campo natural en ambas fases evaluadas (P
Fator de condição e hematologia de tilápias-do-nilo de policultivo com camarão em água salobra
Authors: Brum A. , Caetano Sinfronio L. , Lemos de Mello G. , Laterça Martins M. , Tomas Jerônimo G.
Published: April 2019

Sistemas de policultivo constituem alternativa para a melhor utilização dos recursos disponíveis no ambiente aquático, além de auxiliar na prevenção de enfermidades, porém, seu efeito sobre o estado fisiológico dos peixes é pouco conhecido. Este estudo avaliou o efeito de sistema de policultivo com camarão-branco-do-pacífico (Litopenaeus vannamei) em água salobra sobre os parâmetros hematológicos de tilápia-do-nilo (Orechromis niloticus) em fase de berçário e engorda. Tilápias-do-nilo hígidas em fase de berçário (n=50) e de engorda (n=50) foram coletadas de viveiros de policultivo em Laguna, Sul do Brasil, e analisadas quanto ao fator de condição e parâmetros hematológicos. O fator de condição foi similar em ambas fases de cultivo, com valores próximos a 1. Houve aumento significativo (P
Teor proteico e mineral das silagens de sorgo consorciadas com gramíneas aditivadas com ureia
Authors: Cruz S.S. , Pascoaloto I.M. , Andreotti M. , Lima G.C. , Lattari J.V.F. , Soares D.A. , Morais G.N. , Dickmann L.
Published: April 2019

O conhecimento da dinâmica de cultivo do sorgo consorciado com forrageiras tropicais para produção de silagem é importante tanto para a nutrição animal, visando a qualidade do alimento, como para a sustentabilidade do sistema de produção agrícola. Seguindo essa lógica, o objetivo desta pesquisa foi avaliar os teores de proteína bruta e de macronutrientes das silagens de sorgo forrageiro em cultivo solteiro ou em consórcio com capim-marandu ou capim-mombaça, acrescidas de doses de ureia no momento da ensilagem. O delineamento experimental foi de blocos ao acaso, em fatorial 3 x 5, com os três tipos de silagem (sorgo forrageiro em monocultivo, consorciado com Urochloa brizantha cv. Marandu ou com o Megathyrsus maximus cv. Mombaça) e cinco doses de ureia como aditivo na ensilagem (0; 2,5; 5,0 e 7,5%). Foram determinados os teores de proteína bruta e de macronutrientes (P, K, Ca, Mg e S) antes e após o processo de ensilagem. A adição de doses até 7,5% de ureia no material a ser ensilado é eficiente em aumentar o teor de proteína bruta e de enxofre da silagem. As silagens de sorgo forrageiro consorciado com capim-marandu e capim-mombaça apresentaram maiores teores de proteína bruta, fósforo e potássio que a silagem de sorgo em monocultivo quando não há adição de ureia.
The biotechnological relevance of Rhodococcus rhodochrous. The complete genomic sequence of nitrile biocatalyst strain ATCC BAA-870.
Authors: Frederick Joni , Hennessy Fritha , Horn Uli , Cortés Pilar de la Torre , Broek Marcel van den , Strych Ulrich , Willson Richard C. , Hefer Charles A. , Daran Jean-Marc G. , Sewell Trevor , Otten Linda G. , Brady Dean
Published: April 2019

Background
Rhodococci are industrially important soil-dwelling Gram-positive bacteria that are well known for both nitrile hydrolysis and oxidative metabolism of aromatics. Rhodococcus rhodochrous ATCC BAA-870 is capable of metabolising a wide range of aliphatic and aromatic nitriles and amides. The expressed nitrilase, nitrile hydratase and amidase activities have shown stereoselective preferences for beta-substituted nitrile compounds. The genome of the organism was sequenced and analysed in order to better understand this whole cell biocatalyst.

Results
The genome of R. rhodochrous ATCC BAA-870 is the first Rhodococcus genome fully sequenced using Nanopore sequencing. The circular genome contains 5.9 megabase pairs (Mbp) and includes a 0.53 Mbp linear plasmid, that together encode 7548 predicted protein sequences according to BASys annotation, and 5535 predicted protein sequences according to RAST annotation. The genome contains numerous oxidoreductases, 15 identified antibiotic and secondary metabolite gene clusters, and several terpene and nonribosomal peptide synthetase clusters, as well as 6 putative clusters of unknown type. The 0.53 Mbp plasmid encodes 677 predicted genes and contains the nitrile converting gene cluster. Based on COG functional categories of proteins using RAST annotation, the main distributions of predicted annotated genes belong to known subsystems encoding amino acids and derivatives (19.7%), carbohydrates (13.4%), fatty acids, lipids and isoprenoids (12.2%), and cofactors, vitamins, prosthetic groups and pigments (9.4%). However, 74% of RAST annotated genes are not assigned clear functional roles within known metabolic pathways, and 38% of genes are annotated as hypothetical. BASys annotation predicts that 55% of annotated genes have an unknown function. The R. rhodochrous ATCC BAA-870 genome contains one possible CRISPR, identified by CRISPRCasFinder.

Conclusions
The sequence and comprehensive description of the R. rhodochrous ATCC BAA-870 genome will facilitate the additional exploitation of rhodococci for biotechnological applications, as well as enable further characterisation of this model organism. The genome encodes a wide range of enzymes, many with unknown substrate specificities supporting potential applications in biotechnology, including monooxygenases, cytochrome P450s, reductases, proteases, lipases, and transaminases. The capacity of this strain to hydrolyse nitriles resides upon a plasmid, containing a nitrilase, a low molecular weight nitrile hydratase, and an enantioselective amidase.
Social support and unmet social needs in life after stroke: a cross-sectional observational study
Authors: Lehnerer Sophie Mirabell , Hotter Benjamin , Padberg Inken , Knispel Petra , Remstedt Dike , Liebenau Andrea , Grittner Ulrike , Wellwood Ian , Meisel Andreas
Published: April 2019

Background:
Stroke patients are often affected by long-term disabilities with needs concerning social issues. There is relatively little consideration of social recovery of patients and the support required to return to work, receive social benefits, participate in daily life activities, maintain contact with family and friends and to organize financial affairs. In our study we aimed to investigate if existing tools record social needs adequately. We analyzed the current provision of social support provided in long-term care after stroke and whether unmet social needs were associated with quality of life, caregiver burden, overall function and degree of disability.

Methods:
Our analysis is part of the Managing Aftercare of Stroke study (MAS-I), a cross-sectional observational study of patient needs 2-3 years after initial stroke. Assessment tools included the Nikolaus-score (social situation), the EuroQoL (quality of life), the German Burden Scale for Family Caregivers (caregiver burden), the modified Rankin Scale (disability / dependence), Stroke Impact Scale (function and degree of disability) and the Stroke Survivor Needs Questionnaire (unmet needs).

Results:
Overall 57 patients were included in MAS-I, with ten patients classified in urgent need of socio-economic support according to the Nikolaus-score. Patients with lower than normal Nikolaus-score had a higher degree of disability. Thirty percent of all patients had never received professional social support. Social worker contact happened mostly during the stay in acute hospital or rehabilitation institution. Only four patients (11%) reported long-term support after discharge. Apart from social worker contact during acute care, 43% of patients had unmet needs in the long-term aftercare. Forty percent of all patients included in MAS-I were recommended for social work intervention after an in-depth analysis of their situation. Finally, we saw that unmet social needs were associated with lower quality of life and higher caregiver burden.

Conclusions:
Our data suggest significant unmet needs in social care in long-term stroke patients. Screening tools for unmet social needs such as the Nikolaus-score do not holistically report patients’ needs.
Risk of Stroke-Associated Pneumonia During Hospitalization: Predictive Value of Combined A2DS2 Score and Hyperglycemia
Authors: Li Yang , Zhang Yu , Ma Sheng Lian , Niu Xiaoyuan , Chang Junsen
Published: April 2019

Background: Stroke-associated pneumonia (SAP) is a common complication of cerebrovascular disease. The A2DS2 score has been used to predict the risk of SAP. However, hyperglycemia is not included in this scale. The purpose of the present study was to determine whether combining the A2DS2 scoring system and hyperglycemia can improve the predictive value of the conventional A2DS2 scale for SAP.
Methods: This retrospective study enrolled 2,552 patients with acute ischemic stroke. The A2DS2 scores, fasting blood glucose level and blood glucose level on admission were collected. Regression analysis was used to identify the independent risk factors of SAP. ROC curve analysis was used to evaluate the specificity and sensitivity of the combined A2DS2 score and fasting hyperglycemia for predicting SAP.
Results: Fasting hyperglycemia was an independent risk factor for SAP (OR=2.95; 95% confidence interval: 2.11-4.12; P<0.001). The area under curve of the combined A2DS2 score and fasting hyperglycemia was significantly higher than that of the A2DS2 score alone (0.814 vs. 0.793; P=0.048).
Conclusion: Fasting hyperglycemia is an independent risk factor for predicting SAP. The predictive value of the modified A2DS2 score (combined A2DS2 score and fasting hyperglycemia) is superior to that of A2DS2 score.
Keywords: Stroke-associated pneumonia; A2DS2 score; Fasting hyperglycemia; Predictive value
Experience of using MHT combined with dipyridamole in patients in the early postmenopause
Authors: Sokolova T. M. , Marinkin I. O. , Кuleshov V. M. , Makarov K. Yu.
Published: April 2019

This article presents the evaluation of efficacy of low-dose dipyridamole used to prevent thrombotic complications during menopausal therapy in women in the early postmenopause.
Bronchial asthma: simple solutions of complex issues
Authors: Leshchenko I. V. , Baranova I. I.
Published: April 2019

The problem of achieving control of bronchial asthma (BA), regardless of severity, remains relevant. The use of extra-finely dispersed Beclomethasone/Formoterol FC (EMB FC BDP/FOR) according to the concept of Maintenance and Reliever Therapy (MART) has clinical advantages over traditional basal therapy in combination with symptomatic drugs. In the studies, BA Phenotypes for the use of EMD-FC BDP/FOR: BA in smoking patients, asthma with hyperinflation and asthma in older people and with a disease duration of more than 10 years were established. Clinical cases of treatment of EMD FC BDP/FOR are presented in accordance with the MART concept in older patients with uncontrolled asthma on the background of comorbidities and persistent bronchial obstruction, which have a positive effect and controlled asthma.
Management of cough in the review of current guidelines
Authors: Orlova N. V.
Published: April 2019

Cough is one of the most common symptoms. Cough not only accompanies the respiratory system diseases, but also occurs in diseases of the cardiovascular system, the digestive system, the upper respiratory tract, etc. This is initiated both by the direct irritation of cough receptors in diseases and stimulation of the cough center. The diagnostic search pattern includes endocrine system diseases, systemic diseases, mediastinal lesions, neurological pathology, etc. Not only laboratory and instrumental examination is important for diagnosis, but also a careful assessment of cough characteristics. The diagnosis of chronic cough and the exclusion of lifethreatening causes demand the most attention. The article presents updated CHEST cough guidelines for diagnostic cough search and management algorithms for establishing the main causes of cough. The main groups of drugs used to relieve cough are considered.