bluuebunny/crossref_metadata_2025 huggingface dataset:
Production of Serum Amyloid a in Response to Inflammatory Cytokines by Human Adipocytes
Authors: Calabrò P. , Riegler L. , Limongelli G. , Maddaloni V. , Martone F. , Golia E. , D'Alessandro R. , Pacileo G. , Russo M.G. , Golino P. , Calabrò R.
Published: January 2017

Serum amyloid A (SAA) is a major acute-phase protein in humans, and elevated plasma levels represent a risk factor for cardiovascular diseases. SAA was thought to be produced by hepatocytes only in response to inflammatory stimuli; moreover, recent studies have shown that adipose tissue can secrete several proinflammatory factors. Therefore, we investigated whether cells in adipose tissue can synthesize SAA in response to inflammatory stimuli. Adipocytes and preadipocytes isolated from abdominal adipose tissue were incubated with IL-1, IL-6, TNF-α, LPS, or resistin at different concentrations. After 48 hours, the supernatants were analyzed by ELISAs for human SAA. Preadipocytes did not show any production in SAA. In contrast, in adipocytes, incubation with TNF-α led to a significant increase in SAA production, peaking after LPS or resistin (∼3 times greater vs unstimulated adipocytes). The greatest increase in SAA occurred with all stimuli combined (∼5 times greater vs control cells). Subsequently, we investigated whether treatment with some drugs could modulate SAA production in adipocytes, and observed that fluvastatin led to a significant inhibition of SAA release, whereas a larger modulation of SAA release was observed after treatment with troglitazone or aspirin. These results show for the first time that human adipocytes, and not preadipocytes, can produce SAA in response to inflammatory cytokines and that this process can be modulated.
Decitabine for Acute Myeloid Leukemia in a Patient Undergoing Hemodialysis
Authors: Kourelis T.V. , Moustakakis M.N. , Silk R. , Pharm D. , Boruchov A. , Bilgrami S.F.
Published: January 2017

Treatment of patients with Acute Myeloid Leukemia (AML) undergoing hemodialysis is especially challenging since there are no specific management guidelines for the administration of cytotoxic agents in these patients. Well established chemotherapy protocols may be unsuitable in such cases because of altered drug pharmacokinetics, increased risk for complications, and underlying co-morbidities. In addition, these patients are at an increased risk for complications such as tumor lysis syndrome. Herein, we report the first use of decitabine in a patient on hemodialysis. He presented with a new diagnosis of AML and achieved hematologic remission following the use of induction chemotherapy and maintenance decitabine.
Pharmacological Importance of Simple Phenolic Compounds on Inflammation, Cell Proliferation and Apoptosis with a Special Reference to β-D-Salicin and Hydroxybenzoic Acid
Authors: Mahdi J. , Al-Musayeib N. , Mahdi E. , Pepper C.
Published: January 2017

Simple phenolic (SP) compounds are natural products that exhibit multiple pharmacological functions. The best known of these compounds is β-D-salicin, the first discovered phenolic glycoside and salicylic acid, or 2-hydroxybenzoic acid (2-HBA). Both of these compounds have attracted the interest of scientists in various interdisciplinary fields, including chemistry, pharmacology and medicine. Although β-D-salicin is found in various plants, it is often associated with willow, as it was first discovered in this species of plant. While the presence of glucose in β-D-salicin improves the physicochemical properties of the benzyl moiety, β-D-salicin itself does not have anti-inflammatory or anti-proliferative activity until it is metabolised into 2-HBA in the gastrointestinal tract and blood stream. Likewise, the majority of 2-acetoxybenzoic acid (2-ABA), or acetoxysalicylic acid also undergoes metabolic hydrolysis into 2-HBA. 2-HBA has been shown to play a role in modulating both inflammation and cancer partly through the inhibition of cyclooxygenase-2 (COX-2). It is now clear that 2-HBA most likely acts on the transcription factor NF-κB, which regulates the transcription of COX-2 thereby suppressing inflammation and cell proliferation and promoting apoptosis. Other phenolates, also exhibit anti-inflammation and anti-proliferation activities like the 4-hydroxybenzoate zinc (4-HBZn) complex, which was previously shown to preferentially inhibit COX-2 compared to 2-HBA and ASA. This review aims to collect all the available information related to β-D-salicin and other SP compounds in order to promote a new perspective of this interesting class of compounds and encourage further research into their pharmacological and clinical properties.
Non-communicable diseases during pregnancy in low and middle income countries
Authors: Hussein Julia
Published: January 2017

Apart from the risks of obstetric complications like haemorrhage and eclampsia, a large number of medical conditions affect pregnancy and result in adverse outcomes for both the mother and offspring. Non-communicable diseases in pregnancy are becoming increasingly important in contributing to death and poor health. Changes in the patterns and distribution of these conditions mean that we need new perspectives and ways of dealing with these challenges for the future. This article reviews the burden of ill-health due to non-communicable diseases during pregnancy in low and middle income countries and presents some paradigms relevant to public health and health system needs of the future.
Breadwinner Bonus and Caregiver Penalty in Workplace Rewards for Men and Women
Authors: Bear Julia B. , Glick Peter
Published: January 2017

Two studies examine whether the workplace motherhood penalty and fatherhood bonus are better conceived, respectively, as a caregiver penalty and breadwinner bonus. Participants acting as employers structured offers for married female or male job candidates with children. In Study 1, participants assumed “mother = caregiver” and “father = breadwinner.” These assumptions moderated significantly higher salary offers to fathers and more (explicitly career-dampening) flexible schedules to mothers. Study 2 manipulated family roles (nonparent, parent-unspecified role, parent-breadwinner, and parent-caregiver). Supporting a breadwinner bonus, the female candidate fared best in salary and leadership training offers when labeled a breadwinner (vs. caregiver and unspecified role), equaling a male breadwinner’s offer. A caregiver penalty decreased salary for caregivers of both sexes and leadership training for women (compared to breadwinners) but not men. Thus, the motherhood penalty can become a breadwinner bonus if mothers present themselves as family breadwinners.
Special Treatment as a Recruitment Tool: Issues of Consumer Resistance
Authors: Butori Raphaëlle , Pez Virginie
Published: January 2017

More and more companies tend to give their most recent customers special treatment, thereby using it as a recruitment rather than a rewarding tool. Building on the concepts of legitimacy, reciprocity and inference, we show by means of a quantitative study (N = 301) and a qualitative study that this practice may result in resistance, with consumers either rejecting the brand or adopting opportunistic behavior. These findings enable us to make a series of recommendations for the better use of this CRM tool.
Regimes of Critique and Conflicts of “Worlds”: A Conventionalist Approach to Loyalty Programs
Authors: Maalej Mariem El Euch , Roux Dominique
Published: January 2017

Building on Boltanski and Thévenot's (2006) conventionalist “Economies of Worth” model, this research provides a new theoretical understanding of the difficulty of retaining customers. A qualitative study conducted among 40 consumers reveals that they ground their justifications in a critique of commercial and industrial logic, on the basis of other “worlds” that sustain their frames of judgment.
A Viewpoint on the Leaky Gut Syndrome to Treat Allergic Asthma: A Novel Opinion
Authors: Farshchi Masoumeh Kaboli , Azad Farahzad Jabbari , Salari Roshanak , Mirsadraee Majid , Anushiravani Majid
Published: January 2017

Asthma is a common respiratory disease characterized by airway inflammation, airway hyperreactivity, and reversible airflow obstruction. Despite current treatments, the prevalence of asthma has increased markedly over decades. According to the theories proposed to explain the pathophysiology of autoimmune diseases in integrative medicine, leaky gut syndrome is a phenomenon of increased intestinal permeability due to the disruption of tight junctions and is thought to be related to many chronic diseases, such as food intolerance, inflammatory bowel disease, rheumatoid arthritis, asthma, and other autoimmune disease. One of the classical approaches used by integrative physicians to treat leaky gut syndrome is to repair intestinal permeability to prevent allergic cascade. Due to several mechanisms that have been mentioned in the protective effects of plant gums and plantain family seeds on the intestinal epithelium, we can propose an effective management for leaky gut syndrome to treat asthma.
Larger Than Life
Authors: Harrison Hannah L. , Loring Philip A.
Published: January 2017

Conflicts over natural resources are often misunderstood as being driven primarily by economic concerns or failings of human nature. However, human dimensions research has shown that conflicts are more often driven by problems and shortcomings in institutions for governance and management. In this article, we explore long-standing conflicts over the salmon fisheries of the Kenai River and Upper Cook Inlet region of Southcentral Alaska, fisheries that are embroiled in a long-standing conflict and controversy. We engaged in ethnographic research with participants from commercial, sport, and personal use fisheries in the region to understand their perceptions of these local “salmon wars.” We find that these disputes are more nuanced than is captured by existing typologies of natural resource conflicts, and argue that conflicts can take on a life of their own wherein people stop responding to each other and start responding to the conflict itself, or at least the conflict as they understand it. This perspective is helpful for understanding how conflict in the region has escalated to a point of apparent dysfunction via a process known as schismogenesis. We conclude with a discussion that considers this conflict as an indicator of institutional failure from a social justice perspective, and argue that attempts for conflict management and/or resolution in cases such as these must focus first on protecting the human rights of all participants.
Online-Learning and Its Utility to Higher Education in the Anglophone Caribbean
Authors: Boisselle Laila N.
Published: January 2017

The theoretical piece uses the extant literature to define online-learning, weigh its effects on teaching and learning, and examine its utility in higher education within the Anglophone (English speaking) Caribbean territories. Online-learning is defined here as an integrative application of Information Communication Technologies (ICTs). This article looks at the technical components of online-learning as well as how online-learning is impacted by environmental factors such as institutional policy, democratization, quality assurance, and the rise of the mega-university. This article also considers the coalescence between tools, audience, and environment to suggest on the utility of online-learning to a Caribbean learning community.
Investigating the Factors Affecting Residential Consumer Adoption of Broadband in India
Authors: Manzoor Amir
Published: January 2017

This study aims to explore in detail the factors that affect the consumer behavioral intention to adopt broadband Internet in a developing country perspective. Various attitudinal, normative, and control constructs were identified and investigated for their possible influence on broadband Internet adoption. The empirical data for this study were collected using a self-administered questionnaire that included items related to various attitudinal, normative, and control constructs. Descriptive statistics and regression analysis were used to test these constructs for their possible influence on Indian consumers’ adoption of broadband Internet. The findings suggest that perceived ease of use (PE), social outcomes (SO), hedonic outcomes (HO), service quality (SQ), facilitating conditions resources (FCR), and self-efficacy (SE) were very significant predictors of Indian consumers’ behavioral intention to adopt broadband Internet. This study has multifold significance. The integrated research framework used in this study is an extension of previous well-established research models (such as Model of Adoption of Technology in Households [MATH], Diffusion of Innovation [DOI], and Theory of Planned Behavior [TPB]) and provides an enhanced comprehension of broadband Internet by the Indian household consumers.
Are MENA and Pacific Basin Stock Equity Markets Predictable?
Authors: Elleuch Lahyani Fathia
Published: January 2017

This research uses variance ratio analysis to test whether Middle Eastern, North African (MENA) and Pacific Basin emerging equity markets follow a martingale behavior during the period1980-2004. The conventional Lo and MacKinlay variance ratio test, the multiple variance ratio test of Chow and Denning, rank- and sign-based test of Wright, and wild bootstrap of Kim are used for the monthly return series. The problem of thin trading was addressed using Miller, Muthuswamy, and Whaley’s adjusting procedure. Results have shown traces of a martingale behavior at high holding horizons. However, overall conclusions indicate that the null martingale hypothesis is strongly rejected for the whole sample and considered sub-periods at a 5% significance level. The pattern of the variance ratio estimates signify that the selected stock markets exhibit persistent mean-reverting and predictable behavior in their monthly adjusted returns series. The results expose the ineffectiveness of economic liberalization and privatization measures implemented in the early 1990s to improve their market efficiency. The Asian crisis did not affect the outcomes of the variance ratio analysis. Moreover, it sounds as if the perceptible development in terms of size and liquidity was not sufficient to exhibit a martingale behavior in these markets.
Occupational Health Nursing and the European Dimension
Authors: Staun Julie M. C.
Published: January 2017

This article provides an introduction to and information about the development of the European Union (EU) and the Federation of Occupational Health Nurses within the European Union (FOHNEU).
Occupational Factors and Smoking Cessation among Unionized Building Trades Workers
Authors: Chin Dal Lae , Hong OiSaeng , Gillen Marion , Bates Michael N. , Okechukwu Cassandra A.
Published: January 2017

The purpose of this study was to estimate the contribution of occupational factors to smoking cessation among building trades workers. Longitudinal data came from the MassBUILT smoking cessation intervention study for unionized building trades workers. Multivariable logistic regression analyses were applied to identify the significant predictors of smoking cessation, which was defined as abstinence from smoking during the previous 7 days at the 1-month monitoring and prolonged abstinence for at least 6 months at the 6-month monitoring. Greater concern about exposure to occupational hazards was significantly associated with increased likelihood of smoking cessation at 1 month (odds ratio = 1.06; 95% confidence interval = 1.01–1.11). Additionally, smokers who had a more positive view of their unions had at least marginally increased likelihood of smoking cessation at 1 month. Furthermore, older age, higher levels of educational attainment and household income, and fewer cigarettes smoked per day were important covariates that predicted smoking cessation. Concerns about exposures to work hazards should be incorporated into comprehensive intervention approaches for building trades workers. Additionally, the findings emphasize that blue-collar workers with lower income and education levels and heavy smokers should be considered target groups for implementing cessation interventions.
Factors Associated with Smoking among Operating Engineers
Authors: Choi Seung Hee , Pohl Joanne M. , Terrell Jeffrey E. , Redman Richard W. , Duffy Sonia A.
Published: January 2017

Although disparities in smoking prevalence between white collar workers and blue collar workers have been documented, reasons for these disparities have not been well studied. The objective of this study was to determine variables associated with smoking among Operating Engineers, using the Health Promotion Model as a guide. With cross-sectional data from a convenience sample of 498 Operating Engineers, logistic regression was used to determine personal and health behaviors associated with smoking. Approximately 29% of Operating Engineers currently smoked cigarettes. Multivariate analyses showed that younger age, unmarried, problem drinking, physical inactivity, and a lower body mass index were associated with smoking. Operating Engineers were at high risk of smoking, and smokers were more likely to engage in other risky health behaviors, which supports bundled health behavior interventions.
Respiratory Protection Competencies for the Occupational Health Nurse
Authors: Burns Candace , Lachat Ann M. , Gordon Kimberly , Ryan Mary Gene , Gruden MaryAnn , Barker D. Paxon , Taormina Deborah
Published: January 2017

Approximately 5 million workers employed at 1.3 million work settings are required to wear some form of respiratory protection as part of their jobs. Occupational health nurses can protect the respiratory health of America's workforce. In 2012, the American Association of Occupational Health Nurses Grants Committee Working Group conducted a nationwide survey of occupational health nurses to assess their knowledge, comfort, skills, and abilities relative to respiratory protection. The Working Group used the survey findings as a foundation for the development of respiratory protection competencies for occupational health nurses and a guide for the development of educational modules.
Reducing Obesity among Employees of a Manufacturing Plant
Authors: Giese Karla K. , Cook Paul F.
Published: January 2017

Obesity affects individuals physically and emotionally, contributing to direct and indirect employer costs. Targeted obesity interventions through the Diabetes Prevention Program Lifestyle Core Curriculum offered at the worksite could promote healthy lifestyle decisions resulting in weight improvement among overweight and obese employees. A pretest-posttest cohort design was used to evaluate changes in weight and body mass index among 35 Diabetes Prevention Program participants; they achieved statistically significant changes in body weight ( p < .001) and body mass index ( p < .001). As a process measure, Diabetes Prevention Program session attendance moderately correlated with weight loss (r = .51; p = .002). Many health care professionals, including occupational health nurses, can implement evidence-based worksite obesity interventions to support employee weight loss.
Platelets and neutrophil extracellular traps collaborate to promote intravascular coagulation during sepsis in mice
Authors: McDonald Braedon , Davis Rachelle P. , Kim Seok-Joo , Tse Mandy , Esmon Charles T. , Kolaczkowska Elzbieta , Jenne Craig N.
Published: January 2017

Key Points

In vivo imaging reveals a NET–platelet–thrombin axis that promotes intravascular coagulation in sepsis. Inhibition of NETs during sepsis reduces intravascular coagulation, improves microvascular perfusion, and reduces organ damage.
Platelet secretion is crucial to prevent bleeding in the ischemic brain but not in the inflamed skin or lung in mice
Authors: Deppermann Carsten , Kraft Peter , Volz Julia , Schuhmann Michael K. , Beck Sarah , Wolf Karen , Stegner David , Stoll Guido , Nieswandt Bernhard
Published: January 2017

Key Points

Platelet granule content is dispensable for maintaining vascular integrity during skin and lung inflammation. In stark contrast, lack of platelet granule secretion causes increased mortality in experimental stroke due to intracranial hemorrhage.
The Development and Implementation of Cognitive Aids for Critical Events in Pediatric Anesthesia: The Society for Pediatric Anesthesia Critical Events Checklists
Authors: Clebone Anna , Burian Barbara K. , Watkins Scott C. , Gálvez Jorge A. , Lockman Justin L. , Heitmiller Eugenie S.
Published: January 2017

Cognitive aids such as checklists are commonly used in modern operating rooms for routine processes, and the use of such aids may be even more important during critical events. The Quality and Safety Committee of the Society for Pediatric Anesthesia (SPA) has developed a set of critical-event checklists and cognitive aids designed for 3 purposes: (1) as a repository of the latest evidence-based and expert opinion-based information to guide response and management of critical events, (2) as a source of just-in-time information during critical events, and (3) as a method to facilitate a shared understanding of required actions among team members during a critical event. Committee members, who represented children’s hospitals from across the nation, used the recent literature and established guidelines (where available) and incorporated the expertise of colleagues at their institutions to develop these checklists, which included relevant factors to consider and steps to take in response to critical events. Human factors principles were incorporated to enhance checklist usability, facilitate error-free accomplishment, and ensure a common approach to checklist layout, formatting, structure, and design.

The checklists were made available in multiple formats: a PDF version for easy printing, a mobile application, and at some institutions, a Web-based application using the anesthesia information management system. After the checklists were created, training commenced, and plans for validation were begun. User training is essential for successful implementation and should ideally include explanation of the organization of the checklists; familiarization of users with the layout, structure, and formatting of the checklists; coaching in how to use the checklists in a team environment; reviewing of the items; and simulation of checklist use. Because of the rare and unpredictable nature of critical events, clinical trials that use crisis checklists are difficult to conduct; however, recent and future simulation studies with adult checklists provide a promising avenue for future validation of the SPA checklists. This article will review the developmental steps in producing the SPA crisis checklists, including creation of content, incorporation of human factors elements, and validation in simulation. Critical-events checklists have the potential to improve patient care during emergency events, and it is hoped that incorporating the elements presented in this article will aid in successful implementation of these essential cognitive aids.
The many faces of hematopoietic stem cell heterogeneity
Authors: Crisan Mihaela , Dzierzak Elaine
Published: January 2017

Not all hematopoietic stem cells (HSCs) are alike. They differ in their physical characteristics such as cell cycle status and cell surface marker phenotype, they respond to different extrinsic signals, and they have different lineage outputs following transplantation. The growing body of evidence that supports heterogeneity within HSCs, which constitute the most robust cell fraction at the foundation of the adult hematopoietic system, is currently of great interest and raises questions as to why HSC subtypes exist, how they are generated and whether HSC heterogeneity affects leukemogenesis or treatment options. This Review provides a developmental overview of HSC subtypes during embryonic, fetal and adult stages of hematopoiesis and discusses the possible origins and consequences of HSC heterogeneity.
CFAP157 is a murine downstream effector of FOXJ1 that is specifically required for flagellum morphogenesis and sperm motility
Authors: Weidemann Marina , Schuster-Gossler Karin , Stauber Michael , Wrede Christoph , Hegermann Jan , Ott Tim , Boldt Karsten , Beyer Tina , Serth Katrin , Kremmer Elisabeth , Blum Martin , Ueffing Marius , Gossler Achim
Published: January 2017

Motile cilia move extracellular fluids or mediate cellular motility. Their function is essential for embryonic development, adult tissue homeostasis and reproduction throughout vertebrates. FOXJ1 is a key transcription factor for the formation of motile cilia but its downstream genetic programme is only partially understood. Here, we characterise a novel FOXJ1 target, Cfap157, that is specifically expressed in motile ciliated tissues in mouse and Xenopus in a FOXJ1-dependent manner. CFAP157 protein localises to basal bodies and interacts with tubulin and the centrosomal protein CEP350. Cfap157 knockout mice appear normal but homozygous males are infertile. Spermatozoa display impaired motility and a novel phenotype: Cfap157-deficient sperm exhibit axonemal loops, supernumerary axonemal profiles with ectopic accessory structures, excess cytoplasm and clustered mitochondria in the midpiece regions, and defective axonemes along the flagella. Our study thus demonstrates an essential sperm-specific function for CFAP157 and suggests that this novel FOXJ1 effector is part of a mechanism that acts during spermiogenesis to suppress the formation of supernumerary axonemes and ensures a correct ultrastructure.
An interview with Doug Melton
Authors: Maartens Aidan
Published: January 2017

Doug Melton is Xander University Professor at Harvard University, co-director of the Harvard Stem Cell Institute and a Howard Hughes Medical Institute Investigator. His lab investigates the development of the pancreas, and uses insights from this process to direct the production of insulin-producing beta cells from stem cells. We met Doug at the 2016 Society for Developmental Biology-International Society of Differentiation (SDB-ISD) joint meeting in Boston, USA, where he gave the Jean Brachet Lecture.
Mortality after Peripheral Bypass Surgery: Value of a Mortality Scoring System in Evaluating the Quality of Care
Authors: Klinkert Pieter , van der Steenhoven Tim J. , Vrancken Peeters Mark-Paul F. M. , Breslau Paul J.
Published: January 2017

The objective of this study was to determine the role of a mortality registration in the quality control of patients who died after peripheral bypass surgery. We developed a mortality registration to classify causes of death, to evaluate shortcomings in treatment, and to determine the extent of agreement between pre- and postmortem findings. In a 10-year period, 28 of the 1,022 patients (2.7%) who underwent peripheral arterial reconstruction died. Fifty-three percent of the patients died owing to postoperative complications, most frequently a myocardial infarction. A shortcoming in the medical treatment was observed in only one patient. Forty-three percent of the relatives gave permission for an autopsy. In only two cases, the autopsy report revealed a myocardial infarction that had remained unnoticed during the clinical course. In this selected group of patients undergoing a peripheral bypass operation, the causes of death and the shortcomings in medical care could usually be identified without the help of autopsy data.
Do Vascular Surgeons Improve the Outcome of Carotid Endarterectomy? An Analysis of 12,618 Elective Cases in the State of Connecticut
Authors: Teso Desarom , Edwards Randolph E. , Antezana Jimmy N. , Dudrick Stanley J. , Dardik Alan
Published: January 2017

Because cardiac complications may predict long-term survival after carotid endarterectomy (CEA), this study evaluates contemporary outcome, including cardiac complications, after CEA. Patients in Connecticut hospitals undergoing CEA between 1991 and 2002 were identified using the state discharge database (Chime, Inc.; < www.cthosp.org >). Of the 12,618 CEAs performed, there were 53 (0.4%) deaths, 155 (1.2%) neurologic complications, and 300 (2.4%) cardiac complications. Despite an increase in patient age ( p < .0001, Kruskal-Wallis test) over time, there were decreases in mortality ( p = .0001, chi-square), postoperative stroke ( p = .001), and cardiac complications ( p = .0003). Vascular surgeons performed a minority of the procedures in the state (11%), but there were fewer cardiac complications after CEA performed by vascular surgeons than general surgeons (0.8% vs 3.0%; p < .0001). Multivariable logistic regression demonstrated that the risk of a cardiac complication was elevated in patients operated on by a nonvascular surgeon, patients with previous heart disease or stroke, and the elderly. In a state with very high performance of CEA by general and nonvascular surgeons, postoperative mortality and neurologic complications remain low. However, there were fewer cardiac complications when a vascular surgeon performed the procedure. These results suggest that increased referral to vascular surgeons could improve procedural safety.
Midterm Results of Endoluminal Stent Grafting of the Thoracic Aorta
Authors: Destrieux-Garnier Laurence , Haulon Stéphan , Willoteaux Serge , Decoene Cristophe , Mounier-Vehier Claire , Halna Pascal , Gaudric Julien , Modine Thomas , Beregi Jean-Paul , Koussa Mohamad
Published: January 2017

The purpose of this study was to evaluate the overall outcome of repair of thoracic aortic lesions with endoluminal grafts. Patients were studied prospectively following the implantation of a thoracic endovascular device. Preoperative imaging was performed by helical computed tomography (CT), angiography, transesophageal ultrasonography, or magnetic resonance imaging. Procedures were performed in an endovascular surgical suite under general anesthesia. All patients were evaluated with CT and chest radiography at discharge and at 1, 6, and 12 months. From December 1999 to November 2001, thirty-two patients were enrolled in the study (mean age 62 years; 20 male and 12 female patients). Seventeen patients had dissections, five patients had ruptured aortic ulcer, five patients had traumatic ruptures, three patients had atherosclerotic aneurysms, and two patients had pseudoaneurysms. An American Society of Anesthesiology score of III or IV was evaluated in 22 (69%) patients. The procedure was performed under emergency conditions in 11 cases. All prostheses were implanted successfully. There were no conversions. Three patients (9%) presented with a neurologic event following the implantation procedure, which was lethal in one case (hemorrhagic stroke). Two other patients died during early follow-up of myocardial infarction and multiorgan failure. The early death rate was 9%. The mean follow-up was 13.5 months. During follow-up, the maximal diameter of the aorta shrunk (≥ 5 mm) in 9 (28%) patients, remained stable in 17 (53%) patients, and increased (≥ 5 mm) in 6 (19%) patients. All patients presenting with an increased diameter were initially treated for dissections. A type 1 endoleak was diagnosed on the discharge CT scan in one patient. It sealed spontaneously thereafter. A type 3 endoleak was diagnosed 3 months after the procedure in one patient. A complementary stent graft was implanted in two patients presenting with a dissection with persistent patent false lumen and aortic enlargement. Three patients died during follow-up (two aneurysm-related and one aneurysm-unrelated death). The morbidity and mortality rates reported in our series related to the preoperative morbid conditions of the patients treated. Thoracic aorta endografting is an alternative to open surgery in this subset of patients.
External Femorofemoral Bypass to Relieve Acute Leg Ischemia during Circulatory Assist
Authors: Dosluoglu H. Haldun , Dryjski Maciej L.
Published: January 2017

The development of limb ischemia in patients who are dependent on an intra-aortic balloon pump (IABP) and/or extracorporeal membrane oxygenation (ECMO) is a serious problem. We used external femorofemoral bypass grafting at the bedside as a salvage procedure in two such patients with effective reversal of ischemia, although both died of cardiac complications. This procedure can be considered in patients who are severely coagulopathic and are dependent on IABP and/or ECMO, in whom the graft removal would be considered at the time of balloon removal.
Complications of Reperfusion in Acute Aortic Artery Occlusion Following Saddle Embolization Originating from an Atrial Myxoma
Authors: Ali Tahir , Castro J. , Young C.P. , Burnand K.G.
Published: January 2017

A 58-year-old man presented to the hospital with an 8-hour history of acute-onset bilateral lower limb ischemia. A large saddle embolus had occluded the aorta and could not be removed by balloon endarterectomy through the femoral arteries. Successful open aortic and femoral thromboembolectomy followed by extensive fasciotomies was accompanied by severe reperfusion injury.

Life-threatening hyperkalemia was associated with three episodes of intraoperative ventricular fibrillation and ventricular tachycardia requiring cardiac massage and defibrillation. A dextrose-insulinbicarbonate infusion was required to correct the hyperkalemia. Rhabdomyolysis developed at 24 hours, causing marked myoglobinuria and acute renal failure, which required hemofiltration.

Histology of the recovered embolus confirmed an atrial myxoma, and when the patient had fully recovered, open cardiac surgery was carried out to resect the tiny stump of residual myxoma.

Rhabdomyolysis associated with a myxomatous saddle embolus has not been previously reported. This case highlights the need for pre- and perioperative measures to be taken to overcome hyperkalemia and acute renal failure when revascularizing acute, massive, prolonged ischemia of the lower body.
Minimum Internal Diameter of the Greater Saphenous Vein Is an Important Determinant of Successful Femorodistal Bypass Grafting that Is Independent of the Quality of the Runoff
Authors: Ishii Yoshiyori , Gossage James A. , Dourado Renato , Sabharwal Tarun , Burnand Kevin G.
Published: January 2017

The greater saphenous vein is assessed as part of the workup for femorodistal bypass surgery in our unit. The aim of this study was to determine whether the minimum internal diameter (MID) of the vein predicted graft patency and limb salvage in femorodistal bypass surgery, independently of the quality of the runoff. A consecutive series of 67 infrainguinal vein bypass grafts were performed on 62 patients with critical lower limb ischemia. All were followed for at least 1 year. The MID of the greater saphenous vein was calculated from preoperative saphenograms, and all of the arteriograms were scored for their runoff using an ad hoc method approved by the Society for Vascular Surgery. The cumulative patency of all vein grafts at 3 years was 59 ± 7% (SE), and the limb salvage was 85 ± 5%. All femoropopliteal bypass grafts were patent at 3 years if the MID of the vein was greater than 3.0 mm. The crural bypass patency was 66 ± 12% for an MID greater than 3.0 mm and only 27 ± 12% for an MID less than 3.0 mm. Every extra point on the runoff score increased the hazard of bypass failure by 16% (95% CI 1.0–34; p < .05). Vein diameter and runoff score were independent of one another ( r2 = -.106). The MID of the greater saphenous vein is a major determinant of outcome in infrainguinal vein bypass surgery independent of the arterial runoff.
Review of a Routine Test of Cardiac Function before Aortic Aneurysm Surgery
Authors: Crow Paul , Neary Bill , Heather Brian P. , Earnshaw Jonothan J.
Published: January 2017

The majority of vascular surgeons employ tests of cardiac function prior to embarking on elective abdominal aortic aneurysm (AAA) repair. This study reviewed the value of measuring preoperative ventricular ejection fraction (VEF). The records of the 207 patients considered for elective AAA repair between 1994 and 2000 were reviewed. In patients who underwent surgery, morbidity and mortality data were retrieved from the vascular department database. These outcomes were correlated with the measured VEFs. In patients turned down for surgery, the reasons were determined from patients' notes, and the role that VEF played in the decision was evaluated. Low VEF did not correlate with postoperative cardiac morbidity or mortality. The range of VEF values in patients turned down for surgery was not significantly different from those who underwent AAA repair. VEF was pivotal in the decision not to operate in only one patient over the 6-year interval. This review found no evidence that routine measurement of VEF prior to elective AAA repair was valuable either in making the decision whether to operate or in predicting outcome and complications. Little or no information was added that could not be gained on simple clinical evaluation of cardiac function.
Institutional Votes at the XIX International Botanical Congress, Shenzhen, 2017: Report of the Special Committee on Institutional Votes
Authors: Funk Vicki A. , Turland Nicholas J.
Published: January 2017

The Special Committee on Institutional Votes was established at the XVIII International Botanical Congress (IBC), in Melbourne in 2011, with the mandate to consider the procedure by which institutional votes are allocated and to report to the XIX IBC in Shenzhen in 2017. The Special Committee contacted institutions worldwide and urged them to update their entries in Index Herbariorum and to request institutional votes for the first time or an increase in allocated votes. The Committee sent its recommendations for changes to the list of institutional votes for the Melbourne IBC to the Bureau of Nomenclature, which, in collaboration with the Special Committee, revised the list to produce the new list for the Shenzhen IBC. This new list was sent to the General Committee for final approval, as required by the International Code of Nomenclature for algae, fungi, and plants. The General Committee approved the list, which is now presented in this report.
Phylogeny and a revised tribal classification of Menispermaceae (moonseed family) based on molecular and morphological data
Authors: Ortiz Rosa del C. , Wang Wei , Jacques Frédéric M.B. , Chen Zhiduan
Published: January 2017

The Menispermaceae, a largely tropical family of dioecious and predominantly climbing plants, have been the subject of various molecular studies that confirmed its monophyly and the para‐ and polyphyly of most of the currently recognized tribes. The newly recognized assemblages have been variously named informally in different studies. Here we present a comprehensive phylogenetic hypothesis of the Menispermaceae based on the analyses of three molecular markers (matK, trnL‐F, ndhF) and 41 morphological characters for the most extensive taxonomic and geographic sampling of the family as compared to earlier studies. Phylogenetic relationships were inferred using maximum parsimony, maximum likelihood, and Bayesian approaches. Our results of the combined molecular and total‐evidence datasets corroborate earlier findings, with an improved support for major clade contents. A new tribal classification of the Menispermaceae is proposed, in which nine clades are grouped within the subfamilies Chasmantheroideae and Menispermoideae, forming themselves two well‐supported clades. Within the Chasmantheroideae, the two clades recovered are here recognized as tribes Burasaieae and Coscinieae; within the Menispermoideae the seven identified clades are recognized as tribes Anomospermeae, Cissampelideae, Limacieae, Menispermeae, Pachygoneae, Spirospermeae, and Tiliacoreae. Of these, Spirospermeae is newly described, while the names, if not the circumscriptions, of the remaining tribes are adopted from earlier treatments. The subfamilies and most tribes here identified are further diagnosed by unique combinations of morphological characters. A few genera not sampled for the molecular analysis are provisionally assigned to the recognized tribes based on their floral, fruit, endocarp, and seed features.
Combined Transapical Transcatheter Aortic Valve Replacement and Thoracic Endovascular Aortic Repair for Severe Aortic Stenosis and Arch Aneurysm
Authors: Zhu Yuanjia , Roselli Eric , Idrees Jay , Kapadia Samir , Svensson Lars
Published: January 2017

An 83-year-old male with multiple comorbidities presented with critical aortic stenosis and a saccular aortic arch aneurysm. Through a mini thoracotomy, a balloon expandable transcatheter aortic valve was delivered transapically. A thoracic stent graft was then delivered through the prosthetic valve and deployed in the arch, while a covered stent was deployed in the left common carotid artery. Three-year postoperative computed tomography showed a thrombosed arch aneurysm with decreased size. This case demonstrates the feasibility of using combined transapical transcatheter technologies to treat multicomponent disease in a high-risk patient during a single operation.
Short Communication: Coral reef lifeform variation around power plant activity: Case study on coastal area of Paiton Power Plant, East Java, Indonesia
Authors: SAPTARINI DIAN , MUKHTASOR MUKHTASOR , RUMENGAN INNEKE F.M.
Published: January 2017

Abstract. Saptarini D, Mukhtasor, Rumengan IFM. 2017. Coral reef lifeform variation around power plant activity: Case study on coastal area of Paiton Power Plant, East Java, Indonesia. Biodiversitas 18: 116-120. Heat water, a waste, generated by industries activity near coastal area had generally higher temperature than sea water. It affected to marine organism which used coastal area as their habitat. Coral reefs as one of coastal productive ecosystem had stenotolerant adaptive nature. That nature made them relatively stay on narrow spanning upon environment changing factors. This study obtained to understand various composition of coral lifeform around steam power plant at district of Paiton in Probolinggo, East Java province. Both coral reef and water observed in five area based on distance of heat water distribution and coral presence. Line transect method was unfold in 30m for sampling. Certain parameter like coral coverage area, diversity, and water temperature were collect as data barrier factor for it presence. The percentage of coral coverage area resulted among 48.37-75.33%, it ranked at middle till good level. ANOVA analysis gave significant different toward inter-location coral lifeform and observation location. The ecosystem consisted as massive (CM), foliose (CF), encrusting (CE) and Acropora branching coral (ACB) were dominantly coral types who living over there.

Keywords: Cooling water, coral branching, lifeform, temperature
Indonesian shrimp resource accounting for sustainable stock management
Authors: ANNA ZUZY
Published: January 2017

Abstract. Anna Z. 2017. Indonesian shrimp resource accounting for sustainable stock management. Biodiversitas 18: 248-256. Shrimp fisheries is a resource of important economic value, and is one of the high-demand commodities. Although regarded as a resource that has the ability to grow relatively quick and allows for a year-round production, these resources could experience declining production, or even extinction, if not managed properly. Planning the management of shrimp fishery stock requires basic information on the stock dynamics, both in terms of its natural production and utilization, through resource accounting, mandated by the Agenda 21 of United Nation Conference on Environment and Development (UNCED), formulated in the System of Integrated Environmental and Economic Accounting (SEEA). This study measures the accounting of the shrimp resources, both physical and monetary. In addition, the study also aims to measure the shrimp resource that can be utilized (fishable biomass), from the balance of resources. The approach used in this study is a standard bioeconomic model, with Fox model to estimate biological parameters, and methods of System of National Accounts of FAO (2004), named recursive model, adapted to the existing data. The results of the analysis, includes the calculation of standing stocks (physical asset account), fishable biomass, depletion, as well as monetary accounts. Result shows that the overall condition of the stock still in surplus, where the standing stocks from 1988 to 2014, are in the range of 200,000 to 900,000 tons yearly, with the monetary value between IDR 500 billion to 2 trillion. The intrinsic growth of shrimp tend to be positive in average, with values in the range of -258,000 tons to 263,890 tons. The trend estimation for the next five years (2015-2020), showed a decrease in the stock, and the stock closed as many as 350,000 tons in 2020. This paper also suggests the policy recommendations for the development and management of shrimp resources, in Indonesia.

Keywords: Bio-economic modelling, fishery accounting, fishery stock management plan, monetary account, physical account, shrimp
Frugivorous bird characteristic of seed disperser in shrubland tropical forest West Java, Indonesia
Authors: PARTASASMITA RUHYAT , MARDIASTUTI ANI , SOLIHIN DEDY DURYADI , WIDJAJAKUSUMAH REVIANY , PRIJONO SITI NURAMALIATI
Published: January 2017

Abstract. Partasasmita R, Mardiastuti A, Solihin DD, Widjajakusumah R, Prijono SN. 2016. Frugivorous bird characteristic of seed disperser in shrubland tropical forest. Biodiversitas 18: 263-268. Java has been experiencing a heavy deforestation in the 16th century. Combined with a densely human population, most forests have changed into open land with shrubs and secondary vegetation. For examples Bulbul, flowerpecker and White-eye are three large groups of frugivorous birds and has been known as an effective seed dispersal agent and fostering vegetation recovery. However, variations in the use of fruit by fruit-eating birds very closely linked to the characteristic morphology and feeding behavior. The proportion of fruit in the diet probably varies widely between species, but, for all the best-studied species, fruit it at last seasonally dominant. It is highly frugivorous, particularly in wet season, and consumes the full range of fruit types within itâ€™s gave limit, defecating (or, sometimes regurgitating) all seeds intact. According to the some reference that fruit consumers such as Bulbuls, Flowerpeckers, and White-eyes are some time is called seed dispersal. But there is no information on seed fate. So, this paper describes the frugivorous bird characteristic of seed disperser shrubland tropical forest at Panaruban, Subang. West Java, Indonesia. Observation of frugivorous birdâ€™s communities was used by capture-recapture method. The frugivorous bird morphology characteristic was measured which consisted of external morphology and digest system morphology. The result shown that frugivorous birds had gape width-height ratio of â‰¥ 0.90. Frugivorous bird thin-walled gizzard relationship with gizzard weight to determine safety of seed exit with feces in a state of is intact. There was strong interaction between frugivorous bird-fruit by gape width-height and fruit diameter.

Keywords: Frugivorous birds, seed dispersal, guild, Panaruban
Short Communication: Larvicidal and antifeedant activities of Kalanchoe daigremontiana against Plutella xylostella larvae
Authors: HIDAYATI DEWI , DARMANTO YUDI , NURHIDAYATI TUTIK , ABDULGANI NURLITA
Published: January 2017

Abstract. Hidayati D, Darmanto Y, Nurhidayati T, Abdulgani N. 2016. Short Communication: Larvicidal and antifeedant activities of Kalanchoe daigremontiana against Plutella xylostella larvae. Nusantara Bioscience 8: 312-315. Larvicidal and antifeedant activities of Kalanchoe daigremontiana polar extract were tested on fourth instar of Plutella xylostella larva using choice test, leaf dipping method and antifeedant capacity test (no choice test). K. daigremontiana polar extract in level of 0.25, 0.5, 0.75, 1, 1.25, and 1.5% were used on choice test to determined the larvae behavior tendencies of an attractant or to be an antifeedant, while on toxicity test were used extract in level of 0.25% and 0.5%, whereas on antifeedant capacity test were in level of 0.75, 1, 1.25, and 1.5%. The Probit analysis resulted that 50% of lethal concentration (LC50) was found at 72 hours exposure of 0,5% polar extract. Effective concentration for antifeedant at 1.25%, while antifeedant capacity percentage was in level of 84.85%.