bluuebunny/crossref_metadata_2025 huggingface dataset:
“Performance bond” e “surety bond” como instrumentos de regulação e concreção de políticas públicas para desenvolvimento nacional após a operação lava-jato
Authors: Nunes Danilo Henrique , Lehfeld Lucas Souza
Published: June 2018

Esse trabalho tem como intuito discutir aspectos jurídicos das garantia de exe-cução do contrato – performance bond – no contexto de sua eventual utiliza-ção como garantia nos contratos administrativos de obra, de fornecimento de bens e de prestação de serviços no Brasil. A análise sobre o assunto passa pela importância da licitação e da livre concorrência decorrente da exigência da apólice pela Administração Pública. A metodologia empregada nesse traba-lho se baseou em recomendações das Normas Brasileiras e artigos científicos. Foi utilizada a pesquisa bibliográfica ancorada em livros, artigos e trabalhos acadêmicos. Com a conclusão do presente trabalho é possível ressaltar que na modalidade Performance Bonds, revela que o instituto pode suprir inúme-ras deficiências do ente estatal contratante, de modo a garantir maior sucesso à plena concretização do objeto licitado.
Gli acquisti eco-sostenibili nel nuovo Codice dei contratti pubblici italiano: considerazioni sul life cycle costing
Authors: Crepaldi Gabriella
Published: June 2018

L’inquadramento normativo degli appalti verdi in Italia - II. Costi, prezzi e offerte più vantaggiose - III. Il costo del ciclo di vita – IV. Il ciclo di vita come canone di pertinenza: cautele – V. Medie-piccole-micro imprese, produzioni chilometri zero e filiera corta – VI. Osservazioni conclusive sulla qualificazione ambientale delle stazioni appaltanti (e degli enti)
Federalismo e mutações constitucionais
Authors: Sampaio José Adércio Leite
Published: June 2018

Os processos informais de mudança da Constituição, também conhecidos como “mutações constitucionais”, ocorreram em diversos Estados federais como uma alternativa às reformas previstas nas normas constitucionais. Por meio deles, altera-se o sentido de enunciados da Constituição sem modificar seu texto. Essas mudanças informais, além de discussões de legitimidade democrática, trazem sérios problemas às exigências de rigidez constitucional e de participação das entidades subnacionais nos processos deliberativos federais, especialmente para promover emendas ou revisão à Constituição.
Student voice: Perspectives on language and critical pedagogy in South African higher education
Authors: Mayaba Nokhanyo Nomakhwezi , Ralarala Monwabisi K. , Angu Pineteh
Published: June 2018

In the past two years, higher education institutions (HEI) have been inundated with students' demands for a decolonised education. Their voice led to the resuscitation of debates on a transformed curriculum. Amongst others, the language question is an issue at the centre of these debates. What students were questioning was the hegemony of English, the slow pace in which universities implement multilingual policies, and lack of clarity on the positioning of African languages as languages of learning and teaching. In this paper, we argue that if higher education aims to address marginalised and new knowledge through a decolonised curriculum, fundamental questions are worth being asked. In particular the questions we are asking and responding to are: "How does student voice become a force for social change?" "How can student voice enable HEIs to deal with the issue of language?" We suggest and support the view that the issue of language should be recognised as a social justice issue, that student voice can enlighten curriculum designers and society on the dangers of reproducing inequalities through the hegemony of English, and that graduate attributes, as an essential notion, should recognise multilingualism as a core skill that students should acquire.
Copyright in the Health Sciences Literature: A Narrative Review
Authors: Goben Abigail , Doubleday Alison F.
Published: June 2018

Health science educators, researchers, and clinicians are regularly faced with challenges surrounding copyright and fair use. However, little is known about how copyright is addressed in the professional literature. In order to identify themes and gaps, the authors undertook a narrative review of articles published in health sciences literature between 2000-2016. Only 154 articles were identified on the topic, which attempted to address areas of concern for educators, researchers, and clinicians across all health science disciplines. Overarching issues were identified including prevalence of misinformation or misunderstandings, particularly around fair use, and the continued need for authoritative copyright education and definition of best practices.
Arabidopsis leaf protoplasting v1
Authors: R Ganguly Diep , Crisp Peter
Published: June 2018

Method for isolating mesophyll protoplasts from Arabidopsis as a system for monitoring RNA stability using transcriptional inhibitors (e.g. cordycepin) under stress treatments (e.g. high-light or hydrogen peroxide treatment). Adapted fromYoo S.-D., Cho Y.-H. & Sheen J. (2007) Arabidopsis mesophyll protoplasts: a versatile cell system for transient gene expression analysis. Nature Protocols 2, 1565–1572.
Study of purinosome assembly in cell-based model systems with de novo purine synthesis and salvage pathway deficiencies v1
Authors: Zikanova Marie
Published: June 2018

The purinosome has been observed in a broad spectrum of cells, but some studies claim that it is an artefact of the constructs used for visualization or stress granules resulting from the exposure of cells to nutrient-reduced growth media. Both may be true depending on the method of observation. To clarify this point, we combined two previously used methods, transfection and immunofluorescence, to detect purinosomes in purinosome-free cells deficient in particular DNPS steps (CR-DNPS cells) and in cells deficient in the salvage pathway, which resulted in construction of the purinosome regardless of purine level (CR-HGPRT cells). To restore or disrupt purinosome formation, we transiently transfected CR-DNPS and CR-HGPRT cells with vectors encoding BFP-labelled wild-type (wt) proteins and observed the normalization of purinosome formation. The CR-DNPS cell line transfected with a DNA plasmid encoding an enzyme with zero activity served as a negative control for purinosome formation.
İlkokullarda okul müdürlerinin mali kaynak gerektiren ihtiyaçları karşılama yolları
Authors: TOKER GÖKÇE Asiye , USLU Ömer Faruk
Published: June 2018

Araştırmanın
amacı, ilkokullarda görev yapan okul müdürlerinin görüşlerinden yararlanarak
ilkokulların mali kaynak gerektiren ihtiyaçlarını belirlemek, bu ihtiyaçlarını
karşılamak için gerekli olan finans kaynaklarını nasıl elde ettiklerini tespit
etmek ve okulların finans ihtiyaçları doğrultusunda okul müdürlerinin çözüm
önerilerini belirlemektir. Araştırmanın çalışma grubunu dokuz ilkokul müdürü
oluşturmaktadır. Araştırma nitel yöntemle yapılmıştır; veri toplamada görüşme
yönteminden yararlanılmıştır.  Araştırmanın verileri yarı yapılandırılmış
görüşmelerle elde edilmiştir. Araştırmada elde edilen verilerin
çözümlenmesinde içerik analizinden yararlanılmıştır. Araştırmada ilkokullarda
mali kaynak gerektiren ihtiyaçlar beş başlık altında toplanmıştır. Bunlar
kırtasiye ihtiyaçları, temizlik ihtiyaçları, fiziksel ihtiyaçlar, bilişim ve
donanım ihtiyaçları ve yardımcı personel ihtiyaçlarıdır. Ayrıca okul müdürleri
bu ihtiyaçlarını, gönüllü veli bağışları, kantin gelirleri, Okul Aile Birliği faaliyetleri, İl ve İlçe Milli
Eğitim Müdürlükleri’nin kantin gelirleri, hayırsever vatandaşlardan alınan bağışlar,
çeşitli sivil toplum kurumlarından alınan yardımlar, yerel yönetimlerden
alınan yardımlar, kermesler, okul içinde yapılan sosyal faaliyetler, okul
bahçesinde bulunan para çekme makinesi, okula gelir sağlamak için yapılan
pilav günleri, yapılan deneme sınavlarından alınan paylar, öğrencilerin aldığı
kaynak kitaplardan alınan paylar, okula alınan fotokopi kağıtlarından alınan
paylar, mahalle muhtarları aracılığı ile elde edilen gelirler olmak üzere15
farklı gelir çeşidi ile karşılamaya çalışmaktadırlar. Okul müdürleri,
okullarının finansal sorunlarının çözümü için velilerin algılarının değiştirilmesi, çevre ve çevre işyerleri ile iyi
ilişkiler kurulması, Okul Aile Birliği aracılığı ile yapılacak çalışmalar,
kermes düzenlemek, kardeş okul bulmak, sponsor firma bulmak, belediyelerden
yardım almak, muhtarlar aracılığı ile maddi kaynak bulmak ve liderlik
özellikleri göstermek gibi öneriler sunmuşlardır.
Sosyal Medyaya İlişkin Okul Yöneticilerinin Görüşleri
Authors: ŞAHİN Münir , ÜSTÜNER Mehmet
Published: June 2018

Bu çalışmanın amacı sosyal medyaya ilişkin okul
yöneticilerinin görüşlerini belirlemektir. Veriler nitel araştırma
desenlerinden olgubilim desenine uygun olarak uzman görüşleri doğrultusunda
geliştirilen görüşme formu ile elde edilmiştir. Araştırmanın çalışma grubunu
Malatya ilinde ortaokul ve lise düzeyindeki okullarda görev yapan 26 okul
yöneticisi oluşturmaktadır. Araştırmanın çalışma grubunun belirlenmesinde ölçüt
örnekleme yöntemi kullanılmıştır. Ses kayıt yöntemi ile veriler toplanmış ve
içerik analiz yöntemi kullanılarak veriler analiz edilmiştir. Araştırmanın
sonucunda, okul yöneticilerinin sosyal medyanın öğrencilerin davranışına
ilişkin görüşlerinin olumlu ve olumsuz davranışlar olarak iki tema altında
toplandığı görülmüştür. Okul yöneticileri “olumlu paylaşımları”, öğrencilerin
“kendilerini geliştirmelerini” önemli olumlu görüşler olarak ifade ederken,
olumsuz görüşlerden en fazla öğrencilerin “bozuk ve küfürlü dil kullanmaları”
ve “kötüye merak uyandırma” görüşlerini ifade etmişlerdir. Sosyal medyanın
akademik başarıya etkisine ilişkin olarak “bilgiye ulaşma” olumlu görüş olarak,
“aşırı zaman harcama” ise olumsuz görüş olarak ifade edilmiştir. Okul
yöneticilerinin en fazla “bilgilenme” ve “kaynak bulma” konularında sosyal
medyanın eğitimi desteklediği görüşlerini paylaşmışlardır. “Zaman kaybına yola
açma”, ve “bağımlılık yapma” ise en önemli engelleyici özellikler olarak ifade
edilmiştir. Bilinçsiz sosyal medya kullanımı bağımlılık yaratmakla birlikte
öğrencilerin istenmeyen davranışlar edinmelerine de neden olmaktadır. En önemli
özelliği iletişim olan sosyal medyanın bilgiye ulaşma ve eğitsel materyal bulma
gibi önemli eğitsel özellikleri bulunmaktadır. Sosyal medya
kullanımına ilişkin olarak bir denetim mekanizmasının geliştirilmesi,
öğrencilerin zamanın önemi konusunda eğitilmeleri, sosyal medyanın eğitsel
amaçlı kullanılmasına yönelik çalışmaların yapılması, sosyal medyanın eğitim
amaçlı kullanımına ilişkin yeni teknik ve metotların geliştirilmesi sosyal
medya kaynaklı olumsuzlukları önlemede etkili olabilir.
DESTINATION MARKETING ACTIVITIES FOR SUSTAINABLE URBAN DEVELOPMENT (FOLLOWING THE EXAMPLE OF THE TOWN OF PLEVEN)
Authors: TSVETANOVA Eva
Published: June 2018

This article aims to present the
specific characteristics of destination marketing as a tool for sustainable
urban development; to explore, analyse and assess the cultural tourism
potential of the town of Pleven, Bulgaria, and to conceptualize a model of
integrated marketing strategy to promote the town of Pleven as a destination
for cultural tourism.
POWER GENERATION FROM COMBUSTED “SYNGAS” USING HYBRID THERMOELECTRIC GENERATOR AND FORECASTING THE PERFORMANCE WITH ANN TECHNIQUE
Authors: ANGELİNE Appadurai Anitha
Published: June 2018

Gasification
and combustion of de-oiled Pongamia Pinnata seed cake is done to produce higher
energy biomass waste heat “syngas” for generating power using hybrid
thermoelectric generator (TEG). A test
rig is fabricated and experiments conducted with synthetic oil (Therminol-55) as the heating fluid under
water and air-cooled methods. The hot side temperature is varied from 200 - 250ºC
while the coolant temperature is maintained at 30 oC for both water
and air respectively. Experimental results showed 22.27% enhancement in
electric power at a constant hot side temperature of 250 ºC under water cooled
method. In addition, simulation results for the above mentioned conditions using
artificial neural networks (ANN) tool
in MATLAB also agreed well with the
sample experimental results. The performance parameters such as open circuit
voltage, maximum output power and matched load resistance are forecasted using
ANN upto maximum possible hot side temperature of 350ºC. Further, the financial
evaluation of Biomass gasified-thermoelectric system ($0.0018/kWh and in terms
of Indian currency is ₨ 0.0676/kWh) is found to be almost negligible on
comparison with other available renewable energy technologies.  
Quantifying Effect Sizes in Randomised and Controlled Trials: A Review
Authors: Erah Patrick O. , Bello Shakirat O. , Ganiyu Kehinde A.
Published: June 2018

Meta-analysis aggregates quantitative outcomes from multiple scientific studies to produce comparable effect sizes. The resultant integration of useful information leads to a statistical estimate with higher power and more reliable point estimate when compared to the measure derived from any individual study. Effect sizes are usually estimated using mean differences of the outcomes of treatment and control groups in experimental studies. Although different software exists for the calculations in meta-analysis, understanding how the calculations are done can be useful to many researchers, particularly where the values reported in the literature data is not applicable in the software available to the researcher. In this paper, search was conducted online primarily using Google and PubMed to retrieve relevant articles on the different methods of calculating the effect sizes and the associated confidence intervals, effect size correlation, p values and I2, and how to evaluate heterogeneity and publication bias are presented.
Prevention of Mother-to-Child Transmission of HIV in Delta State of Nigeria: Evaluation of the Early Infant Diagnosis Program
Authors: J. A. Ibobo , H. Chime , E. U. Nwose
Published: June 2018

Background: The global public health issue of Mother-to-Child Transmission (MTCT) of HIV is being addressed with Prevention of MTCT (PMTCT) strategy. A narrative review has recently been published. Objective: The aim of this study was to determine from an early infant diagnosis program in Delta State if there is reduction in MTCT of HIV. Methods: This was a retrospective study. Three health institutions comprising of one from each of the three senatorial district in Delta State were used for the study. The records of 1080 prenatally exposed babies that had DNA PCR tests between 6 weeks to 18 months were evaluated descriptively. Data mining was from the period of August 2009 to December, 2016. Child followup register was reviewed for information that included, age the child had PCR done, commencement of Antiretroviral Therapy (ART) at birth, if mother was on ART, result of PCR and test done at 18 months. Results: 98.0% of HIV positive mothers were on ART during pregnancy, 98.9% of the infants were on ART at birth, and 93.1% were exclusively breast fed. The outcome of the PMTCT program obtained shows that compared to 100% effectiveness among infants who were compulsorily treated on the basis of their mothers being on treatment, there is 89% efficiency among those who either themselves or their mothers received treatment; but only 17% efficiency was achieved where neither mother nor child is receiving treatment. Conclusion: This study shows that with effective PMTCT intervention, reducing MTCT of HIV is being achieved by the public health service.
Frequency of Gestational Diabetes Mellitus in Pregnant Women Referred to Alavi Hospital in Ardabil, 2017
Authors: Zakeri Anahita , Tabrizian Shervin , Aslanian Roghayeh
Published: June 2018

Background: Gestational Diabetes Mellitus (GDM) is the most common complications of pregnancy that spreading throughout the world and in the past 20 years has increased in range from 10% to 100% among racial groups. GDM cause to maternal and fetal side effects, and in the absence of treatment, it can cause macrosomia, respiratory distress, hypoglycemia, hypocalcemia, and hyperbilirubinemia in newborns. Purpose: The aim of this study was to investigate the frequency of GDM in pregnant women in Ardabil, Iran. Method: This retrospective cross-sectional study was conducted on 4485 pregnant women referred to Alavi hospital in Ardabil from April 2017 to December 2017. Data were extracted from hospital records and analyzed by statistical methods in SPSS version 16. Results: Of all Pregnant women, 256 (5.7%) had GDM. 91.7% of women with GDM had cesarean delivery which of them 75.5% were from urban and 73.2% were in the first parity. The mean age of women with cesarean delivery was 26.96 ± 6.38 years and normal delivery was 27.33 ± 6.44 years. Of women with GDM, 53% had primary education and most of them had no history of abortion and family history of diabetes. Conclusion:Considering the increased frequency of GDM in this study in compare with previous studies, the higher rate of cesarean section among young women with diabetes, doing more studies are essential in future.
Comparison of Ticagrelor with Clopidogrel in Reducing Interleukin-17 and Myeloperoxidase Expression in Thrombus and Improving Postprocedural Coronary Flow in ST-segment Elevation Myocardial Infarction Patients
Authors: Li WenHua , Guo SongQi , Wang Shu , Sun Xin , Li ZhuQin , Sun XinYong , Sun YanMing , Wang LanFeng , Pan Wei
Published: June 2018

Purpose. This study aimed to explore the effects of ticagrelor (a P2Y12 receptor inhibitor) on interleukin (IL)-17 and myeloperoxidase (MPO) expression in coronary thrombus as well as on the coronary blood flow in ST-segment elevation myocardial infarction (STEMI) patients following percutaneous coronary intervention (PCI). Methods. Forty STEMI patients who were admitted to the First Affiliated Hospital of Harbin Medical University between August 1, 2014 and December 30, 2014 were enrolled in this study according to a set inclusion criteria. They were randomized to ticagrelor and clopidogrel groups and treated with 180 mg ticagrelor and 600 mg clopidogrel before PCI, respectively. Intracoronary thrombus aspiration was performed by a physician during PCI. Immunohistochemistry and Western blot analysis were carried out to detect the expression of IL-17 and MPO in the thrombus. Corrected thrombolysis in myocardial infarction frame count (CTFC) was used to evaluate blood flow after PCI. Results. Immunohistochemistry results showed that the average positive staining area percentage of IL-17 and MPO in the clopidogrel group was significantly higher than that in the ticagrelor group. Western blot analysis also showed similar results for IL-17 (clopidogrel 0.71 ± 0.036, ticagrelor 0.50 ± 0.56) and MPO (clopidogrel 0.50 ± 0.040; ticagrelor 0.38 ± 0.06). CTFC was lower in the ticagrelor group than that in the clopidogrel group (P < 0.05). Conclusions. Ticagrelor is more effective than clopidogrel in reducing inflammation thrombosis and improving postprocedural PCI blood flow in STEMI patients. This article is open to POST-PUBLICATION REVIEW. Registered readers (see “For Readers”) may comment by clicking on ABSTRACT on the issue’s contents page.
Giant gluteal lipoma in childhood: a case report
Authors: Ulusoy Tangül Sevgi , Şahin Sevinç
Published: June 2018

Lipomas are the most common benign tumors of mesenchyme. They are soft tissue neoplasm and mobile, well-encapsulated tumors. Lipomas are usually grow slowly and rarely reach a size of more than 2-3 cm. Lesions larger than 5 cm, called giant lipomas. They often appear after 40 years old but rarely can occur in childhood. A 12-year-old male patient had a mass showing rapid growth in the right gluteal region at 6 months. Mass was removed with total excision. Postoperative period was uneventful. In the pathology report, it was confirmed that the lipid tissue was composed of mature adipocytes.
Finger millet and horsegram intercropping systems in replacement series for advantages and weed smothering
Authors: Pradhan Adikant , Patil S. K.
Published: June 2018

The land use efficiency and weed suppression through intercropping plays a pivotal role. A field experiment was carried out on finger millet (Eleusine indica L. Gaertn) –horsegram (Macrotyloma uniflorum (Lam.) Verdc.) mono- and intercropping with various weeding (0, 1, or 2 hand-weeding operations) and row spacing (20 and 30 cm) treatments in the Bastar plateau region of India over consecutive five Kharif seasons (2010/2014). The experimental design was a randomized complete block with eighteen treatments replicated thrice. Five percent significant differences were observed in yield and its economics with and without weeding treatments. Horsegram yield was significantly reduced by Finger millet when intercropped. However, total productivity and land use efficiency were higher under the intercropping system as compared to monocrops of either species. There was a significant reduction in weed density and biomass for the intercropping system over both monocrops. Finger millet facilitated an increase in nodule number and dry weight in horsegram under intercropping over monocrops, moreover, root length of horsegram was greater when intercropped. These findings suggest that intercropping Finger millet and horsegram increase total productivity per unit area improve land use efficiency and suppress weeds. Focussing the experimental findings, Finger millet–horsegram (30 cm) with two weedings may be recommended for yield advantage, higher net income, more efficient utilization of resources, and weed suppression as a biological control in western plateau region of India.
Entrevista a la Dra. Marina Garone Gravier - Cultura gráfica: interfaz de conocimiento
Authors: Szir Sandra
Published: June 2018

Entrevista a la Dra. Marina Garone Gravier, figura referente en el campo de los estudios de la historia del libro y la tipografía en América Latina. Su mirada se desplaza de México a Argentina y comprende desde los comienzos de la imprenta en América hasta la actualidad aportando así una plataforma fundamental para un campo de estudios aún novedoso en la región.
Erotismo y mediatizaciones. Revistas femeninas en la Argentina de la década del 60
Authors: Schaufler María Laura
Published: June 2018

El presente artículo traza un recorrido históricocultural acerca del problema del erotismo en la prensa femenina argentina de la década del 60. Ello supone una contextualización dentro de un marco de los estudios culturales, de géneros y sexualidades y las investigaciones sobre mediatizaciones. La categoría de erotismo ha jugado un papel silencioso en el marco de las ciencias sociales. Como tópico se ha mantenido en los márgenes quizás por el peso de la herencia de la cultura religiosa que lo ha definido como un tema prohibido. Neutralizada, la categoría a menudo ha estado solapada tras la sexualidad –y ésta última asociada estrechamente a la dualidad sexual o de los sexos–. En el plano discursivo y en el marco de la cultura de masas constituyó un tópico de disputa simbólica en la década del 60. Lo decible y lo visible respecto al erotismo sufrió mutaciones, hilvanándose una cesura que resignificó la problemática, redefiniendo lo indecible, dentro de la configuración de una época. Los regímenes semiótico-discursivos indicaban no sólo qué podía y qué debía ver la sociedad acerca de lo erótico sino también cómo debía verlo. Las construcciones discursivas y semióticas en la prensa femenina configuraban una visibilización moderada de este aspecto de la vida social.
Lectores, cultura impresa y prácticas urbanas
Authors: Barizzoni Leo
Published: June 2018

En la actualidad los medios electrónicos parecen ganar la partida. Tablets, celulares, computadoras, nos mantienen constantemente conectados y mucho de lo que leemos nos llega por la vía digital. Pero pese a todos los vaticinios, el medio impreso aún persiste. El soporte papel convive con las pantallas en calles, plazas o trenes. Y en distintos formatos, nos sumergimos, absortos, en su lectura.
El modelo "sostenible" heredado por los instrumentos de sostenibilidad
Authors: Alonso Naveiro Miriam
Published: June 2018

La sostenibilidad, como abanderada de la equidad y el reequilibrio de las disfunciones observadas en las dimensiones social, medioambiental, cultural y económica, se constituyó como la respuesta internacional a los síntomas de colapso. Constituyéndose como la tendencia internacional aceptada, se apostó por su incorporación a todas las políticas públicas tratando de forma progresiva de consolidar la transición de un modelo basado en el crecimiento económico, a un modelo basado en los principios de sostenibilidad urbana. Principio que finalmente se instituyó bajo la nota común denominado Regeneración urbana Integrada.La transición a este modelo urbano sostenible desencadenó la creación de herramientas para el análisis, evaluación y proposición de soluciones para el reequilibrio de las relaciones, ahora desproporcionadas, entre el hombre y el medio. Estas nuevas herramientas, que derivaron en la creación de sistemas de indicadores cuantitativos, serán el núcleo central de la presente investigación que, a través de su análisis, tratara de mostrar la relación que subyace entre la metodología empleada para su definición, el modelo sostenible heredado de los documentos internacionales, y la permanencia de las tendencias insostenibles en los sistemas urbanos.Abstract:Sustainability, as the standard-bearer of equity and rebalancing of dysfunctions observed in the social, environmental, cultural and economic dimensions, was established as the international response to these sings of imminent collapse. Becoming itself as the accepted international trend, the firm commitment to its incorporation in all public policies was established, trying progressively to consolidate the transition from a model based on economic growth to a model based on the principles of urban sustainability. This principle was finally established under the common approach called Integrated Urban Regeneration.The transition to this sustainable urban model triggered the creation of tools for the analysis, evaluation and proposition of solutions for the rebalancing of the unbalanced relationships between human beings and the environment. These new instruments that led to the creation of quantitative indicators systems will be the core of the present research that, through its analysis, will try to show the relationship that underlies the methodology used for its definition, the sustainable model inherited from the international documents, and the permanence of the unsustainable tendencies in the urban systems.
Acute Periacetabular Osteotomy for Recurrent Posttraumatic Dislocation of the Hip
Authors: Arpey Nicholas C. , Holte Andrew J. , Tofte Josef N. , Willey Michael C.
Published: June 2018

Case:

A 23-year-old woman with injury-induced acetabular dysplasia developed subacute recurrent dislocation of the right hip following closed reduction of a traumatic dislocation. The initial dislocation had been associated with small posterior wall and femoral head fractures. The recurrent dislocation was addressed with an acute periacetabular osteotomy (PAO) for hip stabilization and femoral head fragment excision.

Conclusion:

An acute PAO is an unusual yet viable treatment strategy for addressing recurrent dislocation following traumatic fracture-dislocation in patients with posterior wall deficiency and injury-induced hip dysplasia. In the patient described herein, the procedure resulted in early stability, but she developed posttraumatic osteoarthritis at 1 year and 4 months after the injury.
Coronal Fracture of the Lunate in Advanced Kienböck Disease: Reestablishing Midcarpal Congruency to Enable Osteochondral Reconstruction
Authors: Gillis Joshua A. , Higgins James P.
Published: June 2018

Case:

We describe a patient with Bain grade-2b Kienböck disease with a coronal fracture of the distal lunate articular surface with proximal structure collapse. To reestablish midcarpal congruity, we used a bone-anchored suture to repair the coronal split in the lunate in preparation for lunate preservation with osteochondral medial femoral trochlea (MFT) reconstruction.

Conclusion:

In Bain grade-2b Kienböck disease, lunate reconstruction of both the proximal and distal joint surfaces can be performed. Successful reconstruction of the distal articular surface can be achieved using a bone-anchored FiberWire (Arthrex) suture technique. This can be employed in conjunction with an osteochondral MFT reconstruction of the proximal aspect of the lunate. Patients with this commonly encountered coronal fracture of the distal articular surface may be considered candidates for lunate reconstruction via this technique rather than conventional ablative procedures.
Musical Transcendence: A Jazz musician's journey into the heart of Indian Classical music
Authors: Kay Jonathan
Published: June 2018

In this article, I share insights and experiences of my journey from the world of jazz and creative improvising to the traditional training of my Guru that helped me to pioneer the expression of North Indian classical music on the tenor and soprano saxophones. This journey has been an intensive process spanning ten years of practice and training under the close guidance of my Guru. To reach these goals, I sacrificed my Western professional music life in order to live in Kolkata, India and immerse myself in the traditional Indian way of life, and after years of pursuing this path, I have grown as a musician and artist far beyond my expectations.

To this day, there has never been an accomplished saxophonist of North Indian classical music, and hence no Guru or maestro to provide traditional training on the instrument. I feel a great privilege in being a forerunner of North Indian classical music on the saxophone, which has also lead me to research and develop the first Indian-tempered saxophone: the Shrutiphone. My efforts to traditionally render this music on saxophone have been received with great support and enthusiasm from today’s maestros, who have listened to my performances and approved my approach as containing the traditional mood and spirit of the ragas.

During this process, I underwent a cultural assimilation to learn the authentic language and spiritual nature of the ragas, an experience that has radically transformed me and given me a path to find my own voice as a traditional raga musician and a contemporary improviser. In searching for a natural synthesis between both forms of music, I discovered they can be united in their motive and meaning to achieve musical transcendence.

I have organized this article into four main sections:

• Introduction – My roots as a jazz musician

• Part One: Cultural Assimilation – My journey to India and my process of learning Raga music and applying it to the saxophone

• Part Two: My Sadhana – The psychological and spiritual reorientation that led me to this new artistic process

• Part Three: An Integral Synthesis – My vision of uniting the West with the East
Irréductibles défenseurs de la composition improvisée à New York
Authors: Pras Amandine
Published: June 2018

Cette enquête sur la pratique de la composition improvisée a été menée auprès de 12 musiciens professionnels vivant à New York et menant une carrière internationale en tant qu’improvisateurs. Ces musiciens ont été sélectionnés pour la puissance et le caractère unique de leur voix artistique, aussi pour représenter autant que possible les diversités culturelles et générationnelles qui caractérisent cette scène. Après une introduction situant leurs pratiques vis à vis de l’improvisation libre et du free jazz tels que définis dans la littérature, l’article est basé sur des citations issues d’entretiens individuels de ces musiciens, suivant un protocole de recueil et d’analyse rigoureux. Les citations sont organisées selon trois thèmes : leur définition de la composition improvisée ; leurs différentes approches artistiques ; et les liens entre leur pratique musicale et leur philosophie de vie, incluant d’éventuelles connexions politiques et/ou spirituelles.

Cette analyse est illustrée d’extraits vidéo de ces musiciens à partir d’enregistrements réalisés au sein d’un projet de recherche et création plus large, qui fait appel à plusieurs approches méthodologiques pour analyser la pratique de la composition improvisée à New York. Les entretiens individuels à la base de cet article représentent la première partie de ce projet qui découle de l’expérience de terrain de l’auteure en temps que réalisatrice d’enregistrements musicaux professionnels au sein de la scène musicale étudiée.
Roll With It: Brass Bands in the Streets of New Orleans, Matt Sakakeeny; New Orleans Suite: Music and Culture in Transition, Lewis Watts and Eric Porter
Authors: Lefresne Brian
Published: June 2018

Brian Lefresne reviews Roll With It: Brass Bands in the Streets of New Orleans by Matt Sakakeeny and New Orleans Suite: Music and Culture in Transition by Lewis Watts and Eric Porter.
A Home Away From Home – Improviser au 21ème siècle
Authors: Pras Amandine
Published: June 2018

Special issue editor Amandine Pras introduces this issue of Critical Studies in Improvisation / Études critiques en improvisation.
Judging the Singular: Towards a Contingent Practice of Improvisation in Law
Authors: McNeilly Kathryn , Stapleton Paul
Published: June 2018

At present improvisation appears to be a tacit practice within law; regularly used but largely unacknowledged amongst legal practitioners. This article advances the benefits of improvisation and calls for a more conscious and critical practice of improvisation in law. However, in this process of moving from the tacit to the critical it is imperative to avoid an abstract practice of improvisation, as has often been advanced in recent musical improvisation literature. The way in which we propose this can be avoided is by foregrounding contingency. This discussion urging towards a contingent practice of improvisation in law will focus on the role of the judge and judicial improvisation.
Contribution Towards an Ethics of Listening: An Improvising Musician’s Perspective
Authors: Waters Simon
Published: June 2018

The practice of “free-improvised” music would seem to present a privileged site for the study of contingent relations: a world in which individuals dynamically adapt within a network of conduct which constitutes its own meaningfulness; in which sound and touch seem co-extensive. This would seem to be an ideal context for the discovery of empathic and ethical behavior. It is argued here, however, that “doing” empathy is in itself improvisatory, and that improvising can thus be placed centre-stage as an essential adapting and organizing skill, rather than a peripheral or abstruse “aesthetic” conduct.
Improvisation et Parrêsia : Des pratiques politiques de soi
Authors: Granjon Fabien Jean-Georges
Published: June 2018

Pour Bernard Lubat et ses « mosiciens », l’improvisation est une forme de Parrêsia (Foucault). Tenant à la sphère de l’éthique personnelle, elle n’est toutefois pas étrangère à une pratique politique désindividualisée, c’est-à-dire à l’organisation d’un commun en partant du « chaos absolu de différences » (Arendt). À leur manière, Lubat & Cie, en tant qu’« êtres différents » et cultivant leurs singularités d’artistes et de citoyens développent un « style d’existence » qui est un témoignage par la vie manifestant « directement, par sa forme visible, par sa pratique constante et son existence immédiate, la possibilité concrète et la valeur évidente d’une autre vie, une autre vie qui est la vraie vie » (Foucault, 2009 : 170). Ils forment ainsi une communauté qui, de par l’existence même qui est la sienne, tend à donner témoignage de ce qu’est l’art de l’improvisation dans sa vérité, et porte, par là, une charge politique spécifique. L’improvisation est, en cela, une pratique de liberté qui (se) donne à voir et à entendre, au travers des propositions artistiques dont elle est au principe. Elle se fait « mise en scène » d’un politique (une politique de la scène et de la vie) et se présente comme un modèle d’une pratique cumulée de liberté qui produit de la différence, transforme l’individu, sans que le fruit de cette transformation ne soit prévisible à l’avance et sans qu’il soit à même de produire un processus plus large de libération.
The Blooming of Forgetting: Deep Play as a Focus for Improvisation in Community Music
Authors: Gordon Paddy
Published: June 2018

The Blooming of Forgetting is a report on two community music projects grounded in improvisation and deep listening that took place in Melbourne, Australia, in 2016: combining personal reflection and theorising, an attempt is made to analyse what occurs "on the ground" in community music improvisation; what resonances for ideas of community ontology might arise, and why "deep play" could be an ideal zone for such projects to aim towards.
Kıyaslamalı Yenilikçi Eğilim Çözümlemesi Temelleri ve Uygulamaları
Authors: GÜÇLÜ Yavuz Selim
Published: June 2018

Son
zamanlarda birçok hidrolojik ve meteorolojik verilerde artan veya azalan
trendler (eğilimler) ortaya çıkmaktadır. Bu makalede eğilim analizini (çözümlemesi)
herhangi bir kabule gerek duymadan gerçekleştiren Şen’in 1:1 doğru yöntemi ele
alınmıştır. Daha önemlisi, diğer bir adı Yenilikçi Eğilim Çözümlemesi olan bu
yöntem geliştirilmiştir. Yenilikçi Eğilim Çözümlemesi yönteminin temellerine
dayanan Kıyaslamalı Yenilikçi Eğilim Çözümlemesi birbiriyle ilişki içinde
bulunan üç farklı veri dizisinin karşılaştırmasını aynı grafik üzerinde yapmak
için fırsat sunmaktadır ancak verilerin boyutsuzlaştırılması bu uygulamanın temel esaslarındandır. Sonuç
itibariyle birbiriyle ilişkili günlük güneş ışınımı, güneşlenme süresi ve
sıcaklık verilerinin kullanıldığı uygulama sonuçları dört önemli bilgiyi açığa
çıkarabilmektedir. Bu bilgiler, üç farklı zaman dizisinin ayrı ayrı eğilim
çözümlemeleri ve bu üç eğilimin birbirine göre değişimleridir. Meteoroloji Genel
Müdürlüğünden temin edilen veriler Adana, Antakya, Gaziantep ve Şanlıurfa
illerinde bulunan ölçüm noktalarında elde edilmiştir. Ayrıca, her istasyonun Kıyaslamalı Yenilikçi Eğilim Çözümlemesi uygulaması yapıldıktan sonra Yenilikçi Eğilim Çözümlemesi uygulamalarına da yer verilerek yeni yöntemin üstünlüğü gösterilmiştir.
Representaciones sociales acerca del ingreso, permanencia y deserción a semilleros de investigación de la Universidad de San Buenaventura de Medellín extensión armenia
Authors: Andrade Salazar José Alonso , Lozano Gómez Natalia Andrea , Leiva Carvajal Karen , Sepúlveda Cubides Maryury
Published: June 2018

Las representaciones sociales del ingreso, permanencia y deserción de estudiantes Universitarios a Semilleros de Investigación, giran en torno a elementos cognitivos «percepciones, ideas y nociones acerca de los beneficios obtenidos, las participaciones en eventos y el aumento de conocimientos», emocionales «actitudes relacionadas con la empatía/apatía con el coordinador y el grupo, interés y deseo de participar de investigaciones, apoyo institucional» y motivacionales «creencias relacionadas con el estatus, el adelantar trabajo de grado, mejorar la hoja de vida, acceder a un posgrado».
Análisis de artefactos identitarios de la comunidad Indígena Emberá Katío (Resguardo Jaidukama – Ituango, Antioquia –)
Authors: Imbett Vargas Erika Solange , Monterroza Ríos Álvaro David
Published: June 2018

Los resultados del análisis descriptivo y técnico de artefactos identitarios de la comunidad Indígena Emberá Katío del resguardo Jaidukama ubicada en el Municipio de Ituango, Departamento de Antioquia (Colombia), nos muestra que, para comprender las relaciones culturales mediadas por artefactos, es necesario establecer un análisis relacional entre el individuo y el colectivo de personas que lo usan, el contexto cultural y la acción simbólica y material que trasmite el artefacto; este, es el caso del Chindau y el Jawaho, dos objetos con capacidades físicas y mecánicas que cumplen funciones que hacen posibles actividades prácticas cotidianas en la comunidad.
Del desplazamiento del pensar a la interrogación por el hacernos humanos
Authors: Muñoz Gaviria Diego Alejandro
Published: June 2018

Se intenta establecer un pensamiento filosófico que permita la recuperación de la reflexión por el saber –del- ser, actualizar la pregunta por la técnica que para este caso estaría en la interrogación por la gerencia educativa y sus servicios en el contexto ideológico e histórico de las sociedades del gerenciamiento y desnaturalizar los influjos alienantes de la configuración de sujetos y subjetividades gerenciales.
Radiobiologia z punktu widzenia ochrony radiologicznej pacjenta i personelu
Authors: Makowska Monika
Published: June 2018

Przedmiotem niniejszej pracy jest przedstawienie zagadnień dotyczących radiobiologii z punktu widzenia ochrony radiologicznej pacjenta i personelu. Radiobiologia jest to nauka zajmująca się wpływem promieniowania jonizującego na organizmy żywe. Obecnie ten rodzaj promieniowania jest powszechnie stosowany w medycynie, dlatego konieczne jest dokładne poznanie interakcji zachodzących pomiędzy cząsteczkami promieniowania a ośrodkiem, które je absorbuje. Współczesna medycyna nie istnieje bez nowoczesnych metod diagnostycznych. Niestety promieniowanie jonizujące przechodząc przez zdrowe tkanki niszczy jej struktury. Większa wiedza na temat radiobiologii może spowodować zmniejszenie skutków ubocznych promieniowania jonizującego.W pracy wykorzystana została wiedza oparta na licznych publikacjach dotyczących ochrony radiologicznej oraz radiobiologii i fizyki jądrowej. Promieniowanie jonizujące stosowane jest w medycynie od bardzo dawna. Wciąż powstają nowe publikacje dotyczące zastosowania tego rodzaju promieniowania oraz jego wpływu na organizm. Przedstawiono także wpływ niskich dawek na organizm.
Brachyterapia mięsaków tkanek miękkich w lokalizacji uro-genitalnej u dzieci w świetle doniesień konferencji ESTRO35.
Authors: Chyrek Artur Jan
Published: June 2018

Wiosną 2016 roku w Turynie we Włoszech odbyła się kolejna, 35 konferencja naukowa Europejskiego Towarzystwa Radioterapii Onkologicznej (ESTRO). W jej trakcie prezentowany był panel grupy GEC-ESTRO zajmującej się brachyterapią – metodą radioterapii polegającą na bezpośrednim wprowadzeniu izotopu promieniotwórczego w guza lub jego lożę. Artykuł ten ma na celu prezentację doniesień dotyczących brachyterapii mięsaków tkanek miękkich wieku dziecięcego – leczenia, które niesie ze sobą wiele potencjalnych korzyści dla pacjentów pediatrycznych, a nie jest niestety dostępne w Polsce.
Antifungal Proteins with Antiproliferative Activity on Cancer Cells and HIV-1 Enzyme Inhibitory Activity from Medicinal Plants and Medicinal Fungi
Authors: Wong Jack Ho , Ng Tzi Bun , Wang Hexiang , Cheung Randy Chi Fai , Ng Charlene Cheuk Wing , Ye Xiuyun , Yang Jie , Liu Fang , Ling Chen , Chan Ki , Ye Xiujuan , Chan Wai Yee
Published: June 2018

A variety of fungi, plants, and their different tissues are used in Traditional Chinese Medicine to improve health, and some of them are recommended for dietary therapy. Many of these plants and fungi contain antifungal proteins and peptides which suppress spore germination and hyphal growth in phytopathogenic fungi. The aim of this article is to review antifungal proteins produced by medicinal plants and fungi used in Chinese medicine which also possess anticancer and human immunodeficiency virus-1 (HIV-1) enzyme inhibitory activities.
Sex and Gender Differences in the Brain Cholinergic System and in the Response to Therapy of Alzheimer Disease with Cholinesterase Inhibitors
Authors: Giacobini Ezio , Pepeu Giancarlo
Published: June 2018

This review has two aims. First, to examine whether or not sex and gender may influence the
brain cholinergic system in animals and in humans. Second, to examine the available evidence of sexually
dimorphic response to the therapeutic and toxic effects of cholinesterase inhibitors. Animal research
reveals no marked difference in the general morphology of the brain cholinergic system but subtle functional
gender differences have been reported. In humans, gender differences in nucleus basalis of
Meynert (NBM) exist. In animals, some cholinergic neurons express estrogen alpha receptors in females
and androgens in males. It is known that sex hormones exert trophic effects on the cholinergic system.
Females show higher frontal cortex cholinergic activity whereas males have higher activity in the hippocampus.
Gender differences in the pharmacological effects result in higher sensitivity to the toxic effects
of organophosphate cholinesterase inhibitors in males. A stronger and more selective benefit of ChEI
treatment in AD has been reported in men by several authors. Sex and estrogen receptor phenotype may
both influence the response to donepezil and rivastigmine. Hence, aged male and female individuals
might respond differently to ChEI due to either sex-specific differences in structures and function of the
cholinergic system, pharmacokinetics, memory function or in the way aging or AD affects these processes.
Transcriptional Remodeling in Primary Hippocampal Astrocytes from an Alzheimer’s Disease Mouse Model
Authors: Ruffinatti F. , Tapella L. , Gregnanin I. , Stevano A. , Chiorino G. , Canonico P.L. , Distasi C. , Genazzani A.A. , Lim D.
Published: June 2018

Background:

It is well known that alterations in astrocytes occur in Alzheimer’s disease and
reactive astrogliosis is one of the hallmarks of the disease. Recently, data has emerged that suggests that
alterations in astrocytes may also occur early in the pathogenesis of the disease.

Objective:

The aim of present work was to characterize the transcriptional alterations occurring in cultured
astrocytes from 3xTg-AD mouse pups compared to control non-transgenic mice. Furthermore, we
also compared these changes to those reported by others in astrocytes from symptomatic AD mice.

Method:

We conducted a whole-genome microarray study on primary cultured astrocytes from the hippocampus
of 3xTg-AD and non-transgenic mouse newborn pups. We used cross-platform normalization
and an unsupervised hierarchical clustering algorithm to compare our results with other datasets of
cultured or freshly isolated astrocytes, including those isolated from plaque-stage APPswe/PS1dE9 AD
mice.

Results:

We found a set of 993 genes differentially expressed in 3xTg-AD as compared with non-Tg
astrocytes. Over-represented gene ontology terms were related to calcium, cell-cell communication,
mitochondria, transcription, nucleotide binding and phosphorylation. Of note, no genes related to inflammation
were found in cultured 3xTg-AD astrocytes. Comparison with astrocytes isolated from
plaque stage APPswe/PS1dE9 showed that 882 out of 993 genes were selectively changed in primary
3xTg-AD astrocytes while 50 genes were co-regulated and 61 were anti-regulated (regulated in the opposite
direction in the datasets).

Conclusion:

Our data show that in cultured astrocytes from an AD mouse model, transcriptional
changes occur and are different from those reported in models mimicking later stages of the disease.
Ocular Inflammation and Depression: Ophthalmologists’ Perspective
Authors: Sekeroglu Hande Taylan , Sekeroglu Mehmet Ali
Published: June 2018

Inflammation may act throughout all the systems in the body including the brain and contribute
to many pathological processes. This mini-review starts with a brief overview of the literature in respect
with the relation between ocular inflammation and depression. In addition, the discussion is mainly
condensed on relevant studies about two ocular diseases: uveitis and dry eye. With this review, we aim
to summarize the current evidence, potential mechanisms and to provide a clinical point of view to patients
with ocular inflammatory diseases who may also be prone to concurrent depression and depressive
symptoms.