bluuebunny/crossref_metadata_2025 huggingface dataset:
THE EFFECT OF LGBT’S CONTENT IN TIK TOK ON THE ACCEPTANCE OF LGBT BY COLLEGE STUDENTS IN A CAMPUS ENVIRONMENT
Authors: Romadlon Freza Nisfi , Ayuningtyas Ginar , Sundayani Renny
Published: October 2022

As a platform, TikTok is more open to people positing queer content. For example, seeing two men embracing each other, doing make-up on a trans person, or else. Although there are questions about censorship of LGBTQ content, the videos in that space are supportive and sometimes surprisingly confessional.The present study aims to describe the effects of gay content on TikTok social media on students’ acceptance about the presence of gays in the campus environment. The research method used is descriptive quantitative to explain a causal relationship of two variables by collecting data that has been distributed from 100 respondents who were randomly selected using a multistage random sampling. The results of present research show that despite feeling anxious about the existence of gay contents in TikTok social media, the participants accept the existence of gays due to several factors such as the existing culture in those places and peer groups. In addition, there is a relationship between the influence of social media content and the level of self-acceptance with the direction of the relationship being unidirectional because the correlation is positive. Furthermore, the level of influence of social media content correlates with the level of acceptance of gay identity among students.
PARENTS’ PERCEPTIONS OF ONLINE LEARNING METHODS: A QUANTITATIVE STUDY
Authors: NF Jhoanita , Khadijah Siti
Published: October 2022

Online learning may alienate some students as they may be not familiar with it or face some problems such as students’ lack of concentration during online learning, poor internet services, the lack of suitable gadgets to access online learning. Parents, as ones who are responsible for the learning process of their children during online learning may be burdened with online learning approach. Therefore, it seems important to analyze the parents’ perceptions toward online learning to understand their concerns on the efficacy of online learning process.  The present study uses a quantitative approach by distributing a set of questionnaires to 90 parents from a private school in Cirebon, Indonesia. The results of present study show that parents have relatively positive perceptions toward online learning. It can be said that online learning may have some merits toward students’ learning progress.
THE CORRELATION BETWEEN INFERIORITY COMPLEX AND SOCIAL INTERACTIONS IN ADOLESCENTS
Authors: Johan Winda Prastika , Herdiansyah Haris , DIMYATI DINDIN
Published: October 2022

Although inferiority complex may have significant impacts on social interactions, adolescents seem to be unaware or dismiss problems caused by inferiority complex. Thus, investigating inferiority complex and its relationship with social interactions in adolescents may provide more insights on the impacts of inferiority complex toward adolescents. The present study aims to investigate the correlation between inferiority complex and social interactions in adolescents. The present study applies a correlational research. Data is collected using a convenience sampling technique by delivering an online questionnaire to 140 adolescents aged 10 to 19 years old. The findings of the present study show a strong and positive relationship between inferiority complex and social interaction, with a Pearson correlation value of 0.705. Implications and suggestions for further studies are also discussed.
PARTICIPATORY COMMUNICATION OF BEKASI CITY RESIDENTS IN COVID 19 VACCINATION ACTIVITIES
Authors: Hamluddin Hamluddin , Yuniarti Tatik , Nugroho Febrianto , Budiman Sahrul , Primadiansyah Rizqyututa
Published: October 2022

It has been argued that the provision of suitable participatory communication can improve people’s participation especially for taking Covid 19 vaccines. The present study aims to analyze the participatory communication of Bekasi local government to reach their goal, making minimum of 30% Bekasi population receiving vaccine. The present study uses a descriptive qualitative approach through observation, interviews and documentation. Four key informants are interviewed while mass messages from the key informants are observed. The results of present study suggest that participatory communication related to the administration of Covid 19 vaccines to Bekasi residents involve Regional Work Units (SKPD) to the lowest local apparatus such as Neighborhood Association (RT) and Citizens Association (RW).  Messages are spread using WhatsApp Groups of each RT. In addition, residents who have not taken the vaccine will be encouraged to take vaccines at the nearest vaccination posts.
LANGUAGE AND PARTIALITY OF MEDIA
Authors: Nuryadi Nuryadi
Published: October 2022

The present study aims to describe the type of transitivity, logical meaning and point of view from news about blasphemy conducted by Basuki Tjahaja Purnama (BTP), the former governor of Jakarta reported by Kompas, a news website. The present study is grounded under qualitative research with a functional discourse analysis approach. Data is obtained from news about BTP which were published from September to November 2016. The results of the analysis suggest that the most dominant type of transitivity was verbal process, the most dominant participant was verbiage, the most dominant circumstant was location, while the logical meanings found were 178 data out of 220 (80.91%). Discourse field is analyzed through the verbal process which contained rebuttals, clarifications and explanations that BTP did not mean to insult Islam. The social context links the blasphemy of Islam with politics. Kompas website intends to state that there are parties who deliberately take advantage of the blasphemy of Islam for political purposes. Discourse actors are divided into roles, social distance and social status. The prominent roles and social status came from Islamic religious leaders, especially from the religious organizations whose opinion was more favorable to BTP's position while social distance narrates BTP's closeness to Muslims, especially ones in Jakarta.
THE VOLGA-DON CANAL: HISTORIOGRAPHY OF RIVER CONNECTIONS AND ENGINEERING THOUGHT OF THE XIX-XX CENTURIES
Authors:   Russian Academy of Sciences. S.I. Vavilov Institute for the History of Science and Technology, Moscow, Russian Federation, YURKIN IGOR
Published: October 2022

Attempts to connect the Volga and Don rivers (variant: Oka and Don) were made for several centuries until the launch of the Volga-Don Shipping Channel in 1952. The stages of design and construction reflected the historiography created during the XVIII-XXI centuries. It considered the works carried out in the area of convergence of the Volga and Don riverbeds and near the source of the Don at Ivan Lake. The route along which the water transport route was laid was reported, the organization of construction was described, hydraulic structures were listed, their size and operational characteristics were given. The article examines the mutual influence of historical works, as well as their relevance, which has changed taking into account changes in social and scientific and technical requests. The aim of the study was to find out how this historiography was related to the needs of the target groups of its creators and readers-historians and hydraulic engineers who designed the connection. It was found that hydraulic engineers often passed by the research of historians, if such, having novelty, did not contain historical and technical material. It is noted that after the connection of the Volga and the Don was carried out, the literature on its history merged again into a single stream.
Medium resistance to penetration of a rigid tool, taking into account viscosity
Authors: Chanyshev A. I. , Abdulin I. M.
Published: October 2022

The problem of determining the resistance of the medium is solved, taking into account the viscous term according to the data of full-scale measurements of the penetration depth and time to stop under impact. A system of equations has been constructed and a solution has been obtained for estimating the resistance parameters. A series of experiments was carried out on throwing a hand-held pile driver into the ground.
Upgrade the value chains of Russian coal companies and their impact on the industry's resilience in the context of the energy transition
Authors: Goosen E. V. , Nikitenko S. M. , Kindyakov A. A.
Published: October 2022

The article is devoted to assessing the development prospects of the Russian coal industry in modern conditions using the concept of economic resilience, as well as to optimizing coal mining and processing based on the use of promising technologies in accordance with global challenges and the requirements of the energy transition, which deeply affects all key parameters of both the coal industry and countries and regions with significant reserves of energy resources and specializing in their production. One of the key drivers of the new development paradigm is the active formation of new value chains for high-tech products. The authors point out that despite the currently emerging paradigm of a carbon-free concept of energy development, the coal industry can be saved on the basis of a differentiated approach to upgrading value chains that can already be formed at existing coal mining enterprises.
Differentiation of factors affecting the level of energy consumption
Authors: Kartashevich A. A.
Published: October 2022

The gradual development of the economies of the countries is due to the presence of a number of factors. There is an increase in the volume of international trade, an increase in the share of export-import operations in the GDP of most developed countries and global GDP, there is a process of consolidation and expansion of the spheres of activity of corporations. The development of market relations contributed to the consolidation of the volume of consumption of goods by the population, an increase in the welfare of repeated consumption of the usual level of goods for the population. The provision of new demand occurs due to the transformation of resources by factors of production, the creation of new production capacities, and the intensification of commercial efforts. Such processes at the global and macro levels can be analyzed through the growth of countries' GDP, as well as through the ratio of specific GDP and its structure. The growth in the volume of production of goods and services affects the growth in the level of consumption, i.e., the standard of living in general, if the population is sufficiently provided with income. Therefore, it is important to understand which factors have a greater impact on the level of energy consumption, as well as in what dependencies energy consumption is on economic growth now.
Past and Present State of Energy Integration in Eurasian Economic Union
Authors: Ravshanov M. F. , Komarova A. V.
Published: October 2022

The purpose of the study is to analyze the main stages in the development of integration processes in the post-Soviet area and determine the main prerequisites and problems for the development of common energy markets of the Eurasian Economic Union (common electricity market, common gas market, common market for oil and oil products). The article considers the stages of the formation of the Eurasian Economic Union (EEU) in the context of the integration processes that began after the collapse of the USSR and determines the role of the energy sector in the development of integration associations. The article also lists the possibilities of the EAEU member countries in cross-border trade in energy resources, both within the Union and outside it, including separately for the oil and gas market.
Dynamics of economic growth and energy consumption of the different countries
Authors: Novikov A. Y.
Published: October 2022

The purpose of the study is to analyze the dynamics of economic growth and energy consumption indicators in groups of countries that differ in income levels. The article considers the dynamics of changes in GDP, per capita GDP, energy consumption and energy efficiency for the period 2000-2020. The total accumulated changes for the period are also considered. Differences are analyzed and conclusions are drawn about the features of the economic development of countries with high incomes and countries with incomes above and below the middle.
Stages of development of the coal industry in Russia to identify possible scenarios for its development
Authors: Provornaya I. V. , Khaikina A. O.
Published: October 2022

The paper considers the influence of key factors reflecting the transition of the country to "green" energy, on the reduction of the carbon intensity of countries. The identified price of carbon was calculated for the first time for some of the considered countries, and after building a panel data model, the main significant factors were selected. The country's GDP has the greatest impact on carbon intensity, and the price of carbon in terms of influence is similar to the share of renewable energy sources in consumption. Key words: carbon price, greenhouse gases, carbon tax, panel data, climate change, global warming.
Stability of ecological systems of the Arctic zone under the conditions of anthropogenic impact
Authors: Mishenin M. V.
Published: October 2022

In the study of the dynamics of indicators affecting the ecological systems of the Arctic zones of the Russian Federation. A comparative characteristic of the level of damage is shown for high-ranking cities located on the territory of the Arctic Zone of the Russian Federation. The change in the frequency of occurrence, leading to various violations, is analyzed with the allocation of the main elements of environmental damage. The state of pollution of air, water (including pathogens), land resources is excluded.
Development of methodical approaches to forecasting the consumption of petroleum products in the context of changes in taxation and increased environmental restrictions
Authors: Nemov V. Y.
Published: October 2022

The paper provides a short analysis of existing approaches to forecasting the demand for petroleum products. The main trends in the consumption of petroleum products in Russia and the world are analyzed. It is shown that in the conditions of severe environmental restrictions, which are increasingly affecting the economic development of industries and transport, the forecast of demand for petroleum products must be carried out taking into account the specifics of the fiscal and environmental policy of the state.
Mechanisms for the distribution of greenhouse gas emission obligations
Authors: Kozhevin V. D. , Kartashevich A. A.
Published: October 2022

Currently, about forty national jurisdictions and more than twenty cities, countries and regions, which account for almost a quarter of global greenhouse gas emissions, are setting a carbon price as a central component of their efforts to reduce emissions and shift the growth trajectory to a more sustainable basis. Collectively, carbon-pricing tools cover about half of the emissions in these jurisdictions, which is about 12% of global emissions. An increasing number of jurisdictions are approaching carbon pricing by developing and implementing emissions trading systems. In this regard, there is a need to analyze the existing tools for the distribution of greenhouse gas emission obligations in the emissions trading system.
Experience in carrying out work on information planning of the location of MSW accumulation sites in the city of Novosibirsk
Authors: Dubrovsky A. V. , Ershov A. V. , Ilyinykh A. L. , Malygina O. I.
Published: October 2022

Sites for the accumulation of solid municipal waste on the territory of settlements affect the densification of buildings, the reduction of the area of recreational areas, the shortage of car parking spaces. Solid municipal waste accumulation sites are a reserve of land resources. With optimal planning of placement, modern technical equipment, the accumulation sites of solid municipal waste can be reduced. The article discusses the experience of work on the creation of a "Geoinformation database on information about the sites of accumulation of solid municipal waste in the territory of the city of Novosibirsk." Planning of optimal and environmentally safe placement of solid municipal waste accumulation sites has been carried out. Examples of digital models of the location of solid municipal waste accumulation sites on the territory of the city of Novosibirsk are shown. The description of the information contained in the geoinformation database of solid municipal waste accumulation sites is given. It is concluded that the geoinformation database on the data on the sites of solid municipal waste accumulation is a new information product, which contains information on the qualitative, quantitative and spatial characteristics of the sites of solid municipal waste accumulation. Thanks to the possibility of combining data on solid municipal waste accumulation sites with an electronic map of the city, a new original geoinformation product has been created that allows planning the location, as well as requirements for land plots on which solid municipal waste accumulation sites will be located. The logistical tasks of organizing garbage collection will be solved.
The land of Russia: the current state and some trends in its development
Authors: Shcherbakova D. A. , Giniyatov I. A.
Published: October 2022

The article examines the current state of the Russian land fund, performs a comparative analysis of its changes in purpose, intended use and forms of ownership of land for the period from 2009 to 2020, as a result of which some trends in its development are revealed. The basis of the performed research was the information contained in the annual State (national) reports on the state and use of the lands of the Russian Federation for the above-mentioned period of time.
The probabilities of the cut distribution laws
Authors: Mizin V. E. , Ilin A. A.
Published: October 2022

The limit measurement errors in the geodesy are determining for the normal distribution law, But the errors, exceeding the limits are throw aside and accidental errors are obey the cut law. Cut laws are not study enough. The article is leading the results of calculate the probabilities hit accidental measurements errors for intervals σ, 2σ, 2,5σ, 3σ for cut normal and cut logical distribution laws. The analysis was accomplished.The probabilities of the cut normal and normal laws is different immaterial. 0,043 - maximum of the different. The normal law replace to the cut normal law is not recommending. Probabilities of the cut law may to use, when it is allowing to avoid the repetition of the field measurements.
Garbage reform" in Siberia - historical and economic aspects
Authors: Tatarenko V. I. , Ljapina O. P. , Klinovitskaya K. A.
Published: October 2022

The article describes various periods: from the formation of Russian statehood to the next decades of the Russian Federation. The article attempts to analyze the formation and management of waste, as well as the forecast of possible ways to solve the "garbage stress" in the near digital future. On a direct line, Russian President V. V. Putin noted that this is a lot of work across the country. In fact, since Soviet times, no one has ever dealt with it properly before. However, there was probably no waste in such a volume in the old days. Currently, 60 million tons of waste are accumulated in Russia annually. And the first steps in this direction are already being taken [1].
About the features of collecting three-dimensional cadastral information in urban areas
Authors: Begliarov N. S. , Shapovalov D. A.
Published: October 2022

The article deals with the actual problem of information support with 3D models for the system of accounting and registration of real estate objects and systems of "smart city". The authors considered a methodology that allows for continuous modeling of real estate objects in urban areas for the purposes of 3D cadastre and effective management in the "smart city" paradigm. The proposed technique is based on the joint use and processing of laser scanning and aerial photography from UAVs. To study the effectiveness of the proposed technique, a number of experiments were carried out on real objects. The obtained dense point clouds from TLS/MLS and UAVs were combined in the CloudCompare open source software product. As a result of experimental work, the optimal parameters for performing TLS/MLS and aerial photography from UAVs, combining heterogeneous point clouds were determined. The results of experimental work have shown that the proposed technique allows performing 3D modeling of real estate with an accuracy that meets the current requirements of the legislation and various levels of details. The resulting models of real estate objects are suitable for the formation of a single three-dimensional database of cadastral data and can be used as an information basis for the development of public digital services and services, as well as to improve the efficiency of urban management. The proposed solution can be used as one of the methods for collecting spatial data on real estate objects during the transition of the Russian Federation to the 3D cadastre system.
The Relationship Between Crime Levels and Spatial Accessibility to Police Services: The Case of Paraguay
Authors: Recalde Ramirez Luis
Published: October 2022

The impact of spatial accessibility to police services on crime levels is not straightforward. Previous research shows diverging outcomes of police presence over crime. One major reason for this is reporting bias, when higher accessibility creates incentives for higher crime reporting. Unlike other types of crimes, murder is assumed to be immune to reporting bias due to the severity of the offense: virtually all murders are reported. A set of OLS regressions of crimes on the spatial accessibility index with controls shows that an increase of a 1-index point in spatial accessibility (roughly a decrease of 2km in the average minimum distance to the nearest police station and an increase of 1 additional police station within a 5km radius) is associated with a 32 percent decrease in homicides. Overall, greater spatial accessibility to police stations deters murders significantly, and at the same time creates incentives for higher crime reporting.
Skuter ve Bisikletin Kampüs Yolculuklarında Trafik Güvenliğine Etkisi: Sakarya Üniversitesi Örneği
Authors: Köse Muhammed Ali , Kuyumcu Zeliha Çağla , Aslan Hakan
Published: October 2022

Günümüzde otomobiller, trafik tıkanıklığı ve hava kirliliğinin en önemli nedeni olarak görülmektedir. Bu olumsuz nedenlerden dolayı ulaşım, kent yaşamının en sorunlu etkinliği olarak değerlendirilmektedir. Sakarya Üniversitesi kampüsünde, son yıllarda bisiklet yolları ve skuter kullanımı, bu bölgeye yapılan yatırımlar nedeniyle kullanımları önceki yıllara göre artmış ve önem kazanmıştır. Kampüs çevresinin ve kampüs çevresindeki insanların sağlığı düşünüldüğünde, skuter ve bisiklet kullanımı en sağlıklı ve ekonomik ulaşım araçları olarak önümüze çıkmaktadır. Bu çalışmada temel amaç, Sakarya Üniversitesi kampüsünde bulunan ulaşım türlerinin kullanıcılar açısından anket yolu ile değerlendirerek, bu ulaşım türlerinin trafik güvenliğine etkilerini araştırmaktır. Bu araştırma ile kullanıcıların kampüste ulaşım araçlarını ne sıklıkla kullandığı, bisiklet yollarının mevcut durumu, toplum taşıma araçlarının kullanılabilirliği, yolculuk maliyetleri ve kampüs ulaşım altyapısı anket yolu ile saptanmıştır. Toplam 40968 öğrenciden 432’sine yüz yüze anket yapılmıştır. Bu oran %1’e tekabül etmektedir. Aynı şekilde toplam 1506 personelden 171’ine yüz yüze anket yapılmıştır. Bu oran da %11’e karşılık gelmektedir.
Analisis potensi instalasi Pembangkit Listrik Tenaga Surya (PLTS) pada rooftop bank BNI kota Balikpapan Permai
Authors: Kusuma Vicky Andria , Suprapto Sena Sukmananda , Karrang Jenrychk Marcelino Tandi
Published: October 2022

Pemasangan sistem pembangkit listrik tenaga surya dilakukan untuk meningkatkan penerapan energi terbarukan dengan memanfaatkan energi surya. Tersedianya banyak kapasitas energi matahari di balikpapan yang dilewati oleh garis khatulistiwa, serta perkantoran perbankan yang memerlukan keandalan suplai energi menjadi alasan penelitian ini dilakukan. Hasil desain PLTS di gedung Bank BNI Balikpapan Permai telah terbukti memiliki potensi yang baik sehingga dapat terwujud bahkan dalam perubahan kondisi cuaca. Sistem PLTS memiliki total daya yang lebih besar dari total konsumsi daya di Gedung Bank BNI dengan konsumsi daya 33 kW, sedangkan untuk sistem PLTS pada November dayanya 50.784 kW dan daya yang dihasilkan pada Desember adalah 45.696 kW. Sehingga kantor BNI akan mendapatkan surplus daya sebesar 12.696 kW – 17.784 kW, dengan kapasitas total Solar Panel yang digunakan Sebesar 9840 kW.
ABSTRACT
The installation of a solar energy generation system is being carried out in order to increase the use of renewable energy through the use of solar energy. The availability of many solar power capacities behind the equator, as well as banks that require a reliable power supply, are the reasons for this research. The results of the PLTS design in the BNI Balikpapan Permai bank building have shown good potential to be implemented even in changing climatic conditions. The PLTS system has a total power higher than the total power consumption in the BNI bank building with a power consumption of 33 kW, while for the PLTS system in November the power is 50,78 kW and the power generated in December is 5,696 kW. This means that the BNI office receives an electricity surplus of 12,696 kW - 17,78 kW, with a total power of 9,8 0 kW from solar modules used.
Pengaturan kecepatan motor induksi tiga fasa dengan direct torque control menggunakan jaringan saraf tiruan
Authors: Suwarni Suwarni , Prasetia Abdul Muis
Published: October 2022

Pengaturan kecepatan merupakan salah satu permasalahan yang terjadi pada motor induksi. Motor induksi merupakan motor yang paling umum digunakan didunia industri, bisnis transportasi dan lain-lain. Keunggulan motor induksi ialah memiliki rancangan yang sederhana dan kuat, harganya murah, efisiensi tinggi, power factor cukup baik,dan perawatannya lebih mudah. Pada penelitian ini metode pengaturan kecepatan yang digunakan adalah metode Direct Torque Control (DTC) dimana DTC mampu mengatur fluks dan torsi secara langsung serta dapat dilakukan tanpa menggunakan sensor kecepatan. Adapunkontrol yang digunakan yaitu Jaringan Saraf Tiruan (JST) menggunakan Model Reference Control (MRC). Respon plant mampuberadaptasi terhadap nilai dari kecepatan referensi yang diberikan. Hasil pengujian menunjukkan bahwa kontrol JST mampumengendalikan motor induksi dengan respon waktu yang cukup baik, hal ini dapat dilihat saat diberi kecepatan referensi sebesar 150 rad/s didapatkan nilai time constan sebesar 0,8693 s, rise time sebesar 1,2917 s, settling time sebesar 1,5536 s, time delay sebesar 0,622 s serta error steady state sebesar 0,9%
ABSTRACT
Speed regulation was one of the problems that occurred in induction motors. induction motors were the most commonly used motors inindustry world, transportation business and others. The advantages of an induction motor were it had a simple and robust design, low cost, high effeciency, good power factor, and easier maintenance. In this study, the speed regulation method used was the Direct TorqueControl (DTC) method where DTC was able to regulate flux and torque directly and it can be done without using a speed sensor. Thecontrol used was Artificial Neural Networks (ANN) using Model Reference Control (MRC). The plant response was able to adapt to thevalue of reference speed given. The test results showed that the ANN control was able to control the induction motor with a good response time. It can be seen when it was given a reference speed of 150 rad/s, the time constant value of 0.8693 s, rise time of 1.2917 s, settling time of 1.5536 s, delay time of 0.622 s and error steady state of 0.9%.
Implementasi sistem SCADA dengan metode kontrol PID pada motor DC penggerak conveyor belt
Authors: Khairuddin Muhammad , Budi Edi Sulistyo , Amalia Zakiyah , Puspitasari Adelia Dwi , Rahmadani Alfiandi Aulia , Prasetyo Firman Bagus
Published: October 2022

Sistem SCADA (Supervisory Control and Data Acquisition) merupakan teknologi komputer yang banyak digunakan pada sistem kendali di dunia industri saat ini. Pada penelitian ini sistem SCADA digunakan pada plant motor penggerak konveyor karena plant tersebut sangat banyak digunakan di industri, hampir semua jenis industri menggunakan konveyor untuk memindahkan barang dari satu tempat ketempat lainnya. Implementasi kontrol yang digunakan pada penelitian ini adalah metode kontrol PID (Proportional Integral Derivative) yang akan mengoreksi error kecepatan dengan menggunakan rotary encoder sehingga kecepatan putaran motor DC sesuai dengan nilai setpoint yang ditentukan melalui sistem SCADA. Kontroler utama pada sistem ini adalah PLC (Programmable Logic Controller) Siemens S7-1200 yang berperan sebagai RTU (Remote Terminal Unit) pada sistemSCADA. Nilai parameter PID yang ditentukan pada sistem SCADA adalah Kp = 0,25, Ti = 0,8 dan Td= 0,08. Berdasarkan hasil pengujian, sistem SCADA bisa mengendalikan plant dengan baik dengan nilai error steady state sebesar 1,1% - 3,4% baik saat conveyor belt bekerja dengan beban maupun tanpa beban. Dengan sistem SCADA, monitoring sistem bisa dilakukan dari jarak jauh tanpa harus datang langsung ke lokasi tempat plant berada sehingga lebih memudahkan proses monitoring dan kontrol plant di dunia industri.
ABSTRACT
The SCADA (Supervisory Control and Data Acquisition) system is a computer technology that is widely used in control systems in today's industrial world. In this study, the SCADA system was used in a motor conveyor driving because the plant is very widely used in industry, almost all types of industry use conveyors to move goods from one place to another. The control implementation used in this study is the PID (Proportional Integral Derivative) control method which will correct errors of the speed sensor input variable using a rotary encoder so that the DC motor rotation speed match the setpoint value determined through the SCADA system. The main controller in this system is the Siemens S7-1200 PLC (Programmable Logic Controller) which acts as the RTU (Remote Terminal Unit) on the SCADA system. The PID parameter values determined in the SCADA system are Kp = 0.25, Ti = 0.8 and Td = 0.08. Based on the test results, the SCADA system can control the plant well with a steady state error value of 1.1% - 3.4% both when the conveyor belt is working with or without load. With the SCADA system, monitoring the system can be done remotely without having to come directly to the location where the plant is located, making it easier for the process of monitoring and controlling plants in the industrial world.
Tuberosity reconstruction baseplate for shoulder hemiarthroplasty: Morphological design and biomaterial application
Authors: Ding Zhentao , Ju Jiabao , Ma Mingtai , Zhang Yichong , Chen Jianhai
Published: October 2022

Background: Shoulder hemiarthroplasty is prone to tuberosity malposition and migration, reducing the rate of tuberosity healing. We proposed to design a tuberosity reconstruction baseplate to assist in tuberosity integration and to evaluate the mechanical properties of baseplate made from the novel biomaterial carbon fiber reinforced polymer (CFRP) composites.

Methods: The three-dimensional model of native proximal humerus was constructed by computed tomography (CT) data. The morphological design of baseplate was based on the tuberosity contour and rotator cuff footprint. Finite element models were created for different thicknesses of CFRP composites, poly (ether-ether-ketone) (PEEK) and titanium-nickel (TiNi) alloy. The permissible load and suture hole displacements were applied to evaluate the mechanical properties.

Results: The structurally optimized model made of CFRP composites provided superior strength and deformability, compared to the PEEK material and TiNi alloy. Its permissible load was above 200 N and the suture hole displacement was between 0.9 and 1.4 mm.

Conclusion: This study proposed a method for designing tuberosity reconstruction baseplate based on morphological data and extended the application of biomaterial CFRP composites in orthopedics field. The optimized model made of CFRP composites allowed a certain extent of elastic deformation and showed the possibility for dynamic compression of tuberosity bone blocks.
Evaluation of injectable platelet-rich fibrin produced by a simple twice-centrifugation method combined with vacuum sealing drainage technology in the treatment of chronic refractory wounds
Authors: Xue Xin , Bian Yuling , Yang Meng , Wei Wei , Meng Lingmin , Zhang Qingfu , Tao Jianguang
Published: October 2022

Objective: To evaluate the effects of injectable platelet-rich fibrin (i-PRF) produced by a simple twice-centrifugation method combined with vacuum sealing drainage on wound inflammation and scar formation in chronic refractory wounds (CRW).

Methods: A total of sixty-eight patients with CRW who were admitted to our hospital were enrolled in this study. They were then randomly divided into the study group (n = 34) with being treated using negative pressure sealing and drainage technology, and the control group (n = 34) with being treated using injectable platelet-rich fibrin in conjunction with negative pressure sealing and drainage technology. The following were the primary outcomes: scar conditions at 1 and 3 months after the wound was fully healed, wound healing time, hospitalization time, wound healing rate, incidence of adverse reactions, serum inflammatory indices, and pain levels were assessed 1 day before treatment and 14 days after treatment. The secondary outcomes were determined by comparing the proportion of positive bacterial cultures in the two groups on the day before therapy, as well as on the seventh and fourteenth days after treatment.

Results: The wound healing time and hospital stay in the study group were significantly lower than that in the control group (all p < 0.001). The wound healing rate of the study group was significantly higher than that of the control group on the 14th day and 28th day after treatment (all p < 0.001). On the 14th day after treatment, the levels of WBC, CRP, and IL-6 in the study group were lower than those in the control group (all p < 0.001). The positive rate of bacterial culture in the study group was significantly lower than that in the control group on the 7th and 14th day after treatment (all p < 0.05). At 1 month and 3 months after treatment, the VSS score in the study group was lower than that in the control group (all p < 0.001). The total defect rate of the study group was also significantly lower than that of the control group (5.88% vs. 29.41%, p = 0.011).

Conclusion: The i-PRF produced by simple twice-centrifugation method combined with VSD could reduce wound inflammation and improve scar formation in patients with CRW.
Rotaxanes with dynamic mechanical chirality: Systematic studies on synthesis, enantiomer separation, racemization, and chiral-prochiral interconversion
Authors: Ishiwari Fumitaka , Takata Toshikazu
Published: October 2022

Dynamic mechanical chirality of [2]rotaxane consisting of a Cs symmetric wheel and a C2v symmetric axle is discussed via the synthesis, enantiomer separation, racemization, and chiral-prochiral interconversion. This [2]rotaxane is achiral and/or prochiral when its wheel locates at the center of the axle, but becomes chiral when the wheel moves from the center of the axle. These were proved by the experiments on the enantiomer separation and racemization. The racemization energy of the isolated single enantiomers was controlled by the bulkiness of the central substituents on the axle. Furthermore, the chiral-prochiral interconversion was achieved by relative positional control of the components. The present systematic studies will provide new insight into mechanically chiral interlocked compounds as well as the utility as dynamic chiral sources.
Advances in antitumor research of CA-4 analogs carrying quinoline scaffold
Authors: Wang Chao , Chang Jing , Yang Shanbo , Shi Lingyu , Zhang Yujing , Liu Wenjing , Meng Jingsen , Zeng Jun , Zhang Renshuai , Xing Dongming
Published: October 2022

Combretastatin A-4 (CA-4) is a potent inhibitor of tubulin polymerization and a colchicine binding site inhibitor (CBSI). The structure-activity relationship study of CA-4 showed that the cis double bond configuration and the 3,4,5-trimethoxy group on the A ring were important factors to maintain the activity of CA-4. Therefore, starting from this condition, chemists modified the double bond and also substituted 3,4,5-trimethoxyphenyl with various heterocycles, resulting in a new generation of CA-4 analogs such as chalcone, Flavonoid derivatives, indole, imidazole, etc. Quinoline derivatives have strong biological activity and have been sought after by major researchers for their antitumor activity in recent years. This article reviews the research progress of novel CA-4 containing quinoline analogs in anti-tumor from 1992 to 2022 and expounds on the pharmacological mechanisms of these effective compounds, including but not limited to apoptosis, cell cycle, tubulin polymerization inhibition, immune Fluorescence experiments, etc., which lay the foundation for the subsequent development of CA-4 containing quinoline analogs for clinical use.
Pathology and molecular mechanisms of Schistosoma japonicum-associated liver fibrosis
Authors: Liu Zhilong , Zhang Lichen , Liang Yinming , Lu Liaoxun
Published: October 2022

Schistosomiasis has been widely disseminated around the world, and poses a significant threat to human health. Schistosoma eggs and soluble egg antigen (SEA) mediated inflammatory responses promote the formation of egg granulomas and liver fibrosis. With continuous liver injuries and inflammatory stimulation, liver fibrosis can develop into liver cirrhosis and liver cancer. Therefore, anti-fibrotic therapy is crucial to increase the survival rate of patients. However, current research on antifibrotic treatments for schistosomiasis requires further exploration. In the complicated microenvironment of schistosome infections, it is important to understand the mechanism and pathology of schistosomiasis-associated liver fibrosis(SSLF). In this review, we discuss the role of SEA in inhibiting liver fibrosis, describe its mechanism, and comprehensively explore the role of host-derived and schistosome-derived microRNAs (miRNAs) in SSLF. Inflammasomes and cytokines are significant factors in promoting SSLF, and we discuss the mechanisms of some critical inflammatory signals and pro-fibrotic cytokines. Natural killer(NK) cells and Natural killer T(NKT) cells can inhibit SSLF but are rarely described, therefore, we highlight their significance. This summarizes and provides insights into the mechanisms of key molecules involved in SSLF development.
An overview of climate change adaptation and mitigation research in Africa
Authors: Baninla Yvette , Sharifi Ayyoob , Allam Zaheer , Tume Suiven John Paul , Gangtar Ngeh Najibullah , George Ngiamte
Published: October 2022

Research on climate change has increased significantly since the 1970s. There has also been a particular focus on Africa, given its vulnerability to climate change impacts and its urbanization trends that may have massive implications for climate change adaptation and mitigation. Despite the wealth of publications on climate change in Africa, there is a lack of review studies that highlight the overall research landscape. If this status of climate research is clarified, African countries can better deal with climate change. Hence, this paper aims to improve our understanding of the status and trends of research on climate change adaptation and mitigation in Africa. Our review, straddling from 1990 to late 2021, recognizes the foundations that underpin climate change adaptation and mitigation literature. Based on keywords associated with Africa's climate change adaptation and mitigation, we undertook bibliometric research by collecting 3,316 related SCI/SSCI articles. In addition, we provided a thematic evolution over three decades, compartmentalized into four sub-periods (1990–2007; 2008–2014; 2015–2019; 2020–2021). Priority research topics and themes have been dynamic over time, with some core concepts receiving more attention (vulnerability, food, water, and energy security). Although the number of published articles exhibited a rapidly growing trend, their distribution is extremely uneven. Articles were mainly published by institutions from certain parts of the continent, with the University of Cape Town, making the highest contribution. About 72% of the existing studies focused on climate change adaptation, while climate change mitigation was less represented with 22%. The results also showed that researchers have examined not all African countries. South Africa, Ethiopia, and Ghana are hot spots, while most countries are largely neglected. Africa and African countries need to improve their future research ability on climate change mitigation. Assessing climate change risks and measures in African countries should be prioritized.
A prediction model for major adverse cardiovascular events in patients with heart failure based on high-throughput echocardiographic data
Authors: Sun Qinliang , Jiang Shuangquan , Wang Xudong , Zhang Jingchun , Li Yi , Tian Jiawei , Li Hairu
Published: October 2022

Background

Heart failure (HF) is a serious end-stage condition of various heart diseases with increasing frequency. Few studies have combined clinical features with high-throughput echocardiographic data to assess the risk of major cardiovascular events (MACE) in patients with heart failure. In this study, we assessed the relationship between these factors and heart failure to develop a practical and accurate prognostic dynamic nomogram model to identify high-risk groups of heart failure and ultimately provide tailored treatment options.

Materials and methods

We conducted a prospective study of 468 patients with heart failure and established a clinical predictive model. Modeling to predict risk of MACE in heart failure patients within 6 months after discharge obtained 320 features including general clinical data, laboratory examination, 2-dimensional and Doppler measurements, left ventricular (LV) and left atrial (LA) speckle tracking echocardiography (STE), and left ventricular vector flow mapping (VFM) data, were obtained by building a model to predict the risk of MACE within 6 months of discharge for patients with heart failure. In addition, the addition of machine learning models also confirmed the necessity of increasing the STE and VFM parameters.

Results

Through regular follow-up 6 months after discharge, MACE occurred in 156 patients (33.3%). The prediction model showed good discrimination C-statistic value, 0.876 (p < 0.05), which indicated good identical calibration and clinical efficacy. In multiple datasets, through machine learning multi-model comparison, we found that the area under curve (AUC) of the model with VFM and STE parameters was higher, which was more significant with the XGboost model.

Conclusion

In this study, we developed a prediction model and nomogram to estimate the risk of MACE within 6 months of discharge among patients with heart failure. The results of this study can provide a reference for clinical physicians for detection of the risk of MACE in terms of clinical characteristics, cardiac structure and function, hemodynamics, and enable its prompt management, which is a convenient, practical and effective clinical decision-making tool for providing accurate prognosis.
Current state of the art in hypoplastic left heart syndrome
Authors: Birla Aditya K. , Brimmer Sunita , Short Walker D. , Olutoye Oluyinka O. , Shar Jason A. , Lalwani Suriya , Sucosky Philippe , Parthiban Anitha , Keswani Sundeep G. , Caldarone Christopher A. , Birla Ravi K.
Published: October 2022

Hypoplastic left heart syndrome (HLHS) is a complex congenital heart condition in which a neonate is born with an underdeveloped left ventricle and associated structures. Without palliative interventions, HLHS is fatal. Treatment typically includes medical management at the time of birth to maintain patency of the ductus arteriosus, followed by three palliative procedures: most commonly the Norwood procedure, bidirectional cavopulmonary shunt, and Fontan procedures. With recent advances in surgical management of HLHS patients, high survival rates are now obtained at tertiary treatment centers, though adverse neurodevelopmental outcomes remain a clinical challenge. While surgical management remains the standard of care for HLHS patients, innovative treatment strategies continue to be developing. Important for the development of new strategies for HLHS patients is an understanding of the genetic basis of this condition. Another investigational strategy being developed for HLHS patients is the injection of stem cells within the myocardium of the right ventricle. Recent innovations in tissue engineering and regenerative medicine promise to provide important tools to both understand the underlying basis of HLHS as well as provide new therapeutic strategies. In this review article, we provide an overview of HLHS, starting with a historical description and progressing through a discussion of the genetics, surgical management, post-surgical outcomes, stem cell therapy, hemodynamics and tissue engineering approaches.
Hydrogen peroxide suppresses excitability of gonadotropin-releasing hormone neurons in adult mouse
Authors: Rijal Santosh , Jang Seon Hui , Cho Dong Hyu , Han Seong Kyu
Published: October 2022

It has been reported that reactive oxygen species (ROS) derived from oxygen molecule reduction can interfere with the cross-talk between the hypothalamic-pituitary-gonadal (HPG) axis and other endocrine axes, thus affecting fertility. Furthermore, ROS have been linked to GnRH receptor signaling in gonadotropes involved in gonadotropin release. There has been evidence that ROS can interfere with the HPG axis and gonadotropin release at various levels. However, the direct effect of ROS on gonadotropin-releasing hormone (GnRH) neuron remains unclear. Thus, the objective of this study was to determine the effect of hydrogen peroxide (H2O2), an ROS source, on GnRH neuronal excitabilities in transgenic GnRH-green fluorescent protein-tagged mice using the whole-cell patch-clamp electrophysiology. In adults, H2O2 at high concentrations (mM level) hyperpolarized most GnRH neurons tested, whereas low concentrations (pM to μM) caused slight depolarization. In immature GnRH neurons, H2O2 exposure induced excitation. The sensitivity of GnRH neurons to H2O2 was increased with postnatal development. The effect of H2O2 on adult female GnRH neurons was found to be estrous cycle-dependent. Hyperpolarization mediated by H2O2 persisted in the presence of tetrodotoxin, a voltage-gated Na+ channel blocker, and amino-acids receptor blocking cocktail containing blockers for the ionotropic glutamate receptors, glycine receptors, and GABAA receptors, indicating that H2O2 could act on GnRH neurons directly. Furthermore, glibenclamide, an ATP-sensitive K+ (KATP) channel blocker, completely blocked H2O2-mediated hyperpolarization. Increasing endogenous H2O2 by inhibiting glutathione peroxidase decreased spontaneous activities of most GnRH neurons. We conclude that ROS can act as signaling molecules for regulating GnRH neuron’s excitability and that adult GnRH neurons are sensitive to increased ROS concentration. Results of this study demonstrate that ROS have direct modulatory effects on the HPG axis at the hypothalamic level to regulate GnRH neuron’s excitabilities.