bluuebunny/crossref_metadata_2025 huggingface dataset:
Understanding the Concept of Chronotherapeutics in the Management of Diabetes Mellitus
Authors: Kashyap Shilpi , Bala Rajni , Behl Tapan
Published: October 2020

The circadian rhythms have been controlled with the aid of a circadian clock in the hypothalamus
region, which is known as the suprachiasmatic nucleus. Chronotherapeutics, a branch
of pharmacotherapeutics, plays a mandatory role in the treatment of various disorders, such as delivering
the drug in the correct schedule, correct site, and correct extent and provides benefit to the
patients. The chronopharmacological aspects are very much important in the treatment of diabetes
mellitus during daytime as the patients’ timing of daily activities of body and medicine treatment
has an impact on the increase in the glucose levels in the blood. This leads to the fact that the increased
risk of obesity and diabetes gets worse, ultimately increasing the rates of cardiovascular diseases
and deaths. According to a medical saviour who works on the problems related to diabetes,
the level of glucose in plasma changes independently as regard to eating habits and use of insulin
and medicines. People suffering from dawn phenomenon are difficult to manage, hence, the basic
aim is to detect the functioning of the biological clock of human body and its chronotherapeutic effect
on human beings that increases the therapeutic effects and reduces side effects. Keeping these
points in mind, an attempt has been made in the present review to discuss the role of chronotherapy
in the management of diabetes, various techniques used in formulation and design of chronotherapeutic
drug delivery systems and regulatory issues related to chronotherapeutics.
Effects of Consuming Catha Edulis Forsk (khat)on the Gene Manifestation of CHRM1 and CHRM3 in relation to Salivary Glands, Saliva Flow Rates, pH and Dental Caries in Yemeni Consumers
Authors: Alshahrani Sawsan Abdullah , Almufareh Nawaf Abdulrahman , Almarshady Bandary , Alotaibi Rasil Khaled , Al-Qahtani Wedad Saeed
Published: October 2020

Background:

The current study has been conducted to estimate the impact of Catha Edulis Forsk (simply known as khat) on pH and saliva flow rate in teeth unaffected by caries among patients from Arab, Yemen, consuming the plant. The goal was to evaluate the relation of these indicators with gene manifestation ofCHRM1andCHRM3,which contributes to the regulation of saliva secretions.

Methods:

Overall, 60 respondents aged between 27 and 54 years were selected for the research. They were distributed among two groups, group I and group II, including 30 respondents equally. Group I incorporated respondents consuming no khat, having teeth caries, adequate saliva flow, and generally, healthy oral cavity. In turn, group II incorporated respondents consuming khat having caries-free teeth, inadequate saliva flow and relatively unhealthy oral cavity. Saliva samples were taken from all respondents. They were analyzed for indicators of flow rate as well as pH of saliva. Salivary gland biopsy specimens have also been taken. The whole RNA was allocated, cDNA synthesized and reinforced to estimate the gene manifestation ofCHRM1andCHRM3.

Results:

A considerable rise in the mean salivary flow rate along with a drastic decline in the mean salivary pH within caries-free teeth among the respondents consuming khat was observed during the study. The mRNA expressionsCHRM1andCHRM3were significantly increased among participants consuming khat. Results were contrasted to the control group of patients not consuming khat.

Conclusion:

The characteristics of salivary flow rate, pH, and caries-free teeth have been related to the gene manifestations ofCHRM1andCHRM3in respondents consuming khat.
Ionic Liquid Catalyzed Efficient Regioselective Synthesis of 1,4-Disubstituted 1,2,3-Triazoles Under Metal and Solvent Free Conditions
Authors: Banday Abid H. , Hruby Victor J.
Published: October 2020

Background:

Catalyzed organic reactions avoiding the use of metal salts, metal complexes
and organometallic compounds have tremendous applications especially within sensitive biological
systems. The current work is an effort towards metal and solvent-free organo-catalyzed reactions.

Objective:

Unprecedented, one-pot regioselective synthesis of 1,4-disubstituted 1,2,3-triazoles
through azide-aldehyde (3+2) organo-click cycloaddition under metal and solvent-free conditions
is described.

Methods:

The method presents a convenient approach towards the synthesis of functionally versatile
1,4-disubstituted 1,2,3-triazoles from easily accessible substrates using recyclable 1,8-diazabicyclo[
5.4.0]undec-7-ene (DBU)-based ionic liquids as catalysts.

Results:

1,4-disubstituted 1,2,3-triazoles were obtained in moderate to excellent yield using azidealdehyde
(3+2) organo-click cycloaddition under metal and solvent-free conditions.

Conclusion:

The procedure reported herein for the synthesis of 1,4-disubstituted 1,2,3-triazoles is
straightforward, greener, devoid of tedious workups and chromatographic separation.
Evaluating Patient-Centered Mobile Health Technologies: Definitions, Methodologies, and Outcomes
Authors: Bruce Courtenay , Harrison Patricia , Giammattei Charlie , Desai Shetal-Nicholas , Sol Joshua R , Jones Stephen , Schwartz Roberta
Published: October 2020

Several recently published studies and consensus statements have demonstrated that there is only modest (and in many cases, low-quality) evidence that mobile health (mHealth) can improve patient clinical outcomes such as the length of stay or reduction of readmissions. There is also uncertainty as to whether mHealth can improve patient-centered outcomes such as patient engagement or patient satisfaction. One principal challenge behind the “effectiveness” research in this field is a lack of common understanding about what it means to be effective in the digital space (ie, what should constitute a relevant outcome and how best to measure it). In this viewpoint, we call for interdisciplinary, conceptual clarity on the definitions, methodologies, and patient-centered outcomes frequently used in mHealth research. To formulate our recommendations, we used a snowballing approach to identify relevant definitions, outcomes, and methodologies related to mHealth. To begin, we drew heavily upon previously published detailed frameworks that enumerate definitions and measurements of engagement. We built upon these frameworks by extracting other relevant measures of patient-centered care, such as patient satisfaction, patient experience, and patient activation. We describe several definitional inconsistencies for key constructs in the mHealth literature. In an effort to achieve clarity, we tease apart several patient-centered care outcomes, and outline methodologies appropriate to measure each of these patient-care outcomes. By creating a common pathway linking definitions with outcomes and methodologies, we provide a possible interdisciplinary approach to evaluating mHealth technologies. With the broader goal of creating an interdisciplinary approach, we also provide several recommendations that we believe can advance mHealth research and implementation.
A Data Visualization and Dissemination Resource to Support HIV Prevention and Care at the Local Level: Analysis and Uses of the AIDSVu Public Data Resource
Authors: Sullivan Patrick Sean , Woodyatt Cory , Koski Chelsea , Pembleton Elizabeth , McGuinness Pema , Taussig Jennifer , Ricca Alexandra , Luisi Nicole , Mokotoff Eve , Benbow Nanette , Castel Amanda D , Do Ann N , Valdiserri Ronald O , Bradley Heather , Jaggi Chandni , O'Farrell Daniel , Filipowicz Rebecca , Siegler Aaron J , Curran James , Sanchez Travis H
Published: October 2020

Background

AIDSVu is a public resource for visualizing HIV surveillance data and other population-based information relevant to HIV prevention, care, policy, and impact assessment.

Objective

The site, AIDSVu.org, aims to make data about the US HIV epidemic widely available, easily accessible, and locally relevant to inform public health decision making.

Methods

AIDSVu develops visualizations, maps, and downloadable datasets using results from HIV surveillance systems, other population-based sources of information (eg, US Census and national probability surveys), and other data developed specifically for display and dissemination through the website (eg, pre-exposure prophylaxis [PrEP] prescriptions). Other types of content are developed to translate surveillance data into summarized content for diverse audiences using infographic panels, interactive maps, local and state fact sheets, and narrative blog posts.

Results

Over 10 years, AIDSVu.org has used an expanded number of data sources and has progressively provided HIV surveillance and related data at finer geographic levels, with current data resources providing HIV prevalence data down to the census tract level in many of the largest US cities. Data are available at the county level in 48 US states and at the ZIP Code level in more than 50 US cities. In 2019, over 500,000 unique users consumed AIDSVu data and resources, and HIV-related data and insights were disseminated through nearly 4,000,000 social media posts. Since AIDSVu’s inception, at least 249 peer-reviewed publications have used AIDSVu data for analyses or referenced AIDSVu resources. Data uses have included targeting of HIV testing programs, identifying areas with inequitable PrEP uptake, including maps and data in academic and community grant applications, and strategically selecting locations for new HIV treatment and care facilities to serve high-need areas.

Conclusions

Surveillance data should be actively used to guide and evaluate public health programs; AIDSVu translates high-quality, population-based data about the US HIV epidemic and makes that information available in formats that are not consistently available in surveillance reports. Bringing public health surveillance data to an online resource is a democratization of data, and presenting information about the HIV epidemic in more visual formats allows diverse stakeholders to engage with, understand, and use these important public health data to inform public health decision making.
Preservation of Person-Centered Care Through Videoconferencing for Patient Follow-up During the COVID-19 Pandemic: Case Study of a Multidisciplinary Care Team (Preprint)
Authors: Silsand Line , Severinsen Gro-Hilde , Berntsen Gro
Published: October 2020

BACKGROUND

The Patient-Centered Team (PACT) focuses on the transitional phase between hospital and primary care for older patients in Northern Norway with complex and long-term needs. PACT emphasizes a person-centered care approach whereby the sharing of power and the patient’s response to “What matters to you?” drive care decisions. However, during the COVID-19 pandemic, videoconferencing was the only option for assessing, planning, coordinating, and performing treatment and care.

OBJECTIVE

The aim of this study is to report the experience of the PACT multidisciplinary health care team in shifting rapidly from face-to-face care to using videoconferencing for clinical and collaborative services during the initial phase of the COVID-19 pandemic. This study explores how PACT managed to maintain person-centered care under these conditions.

METHODS

This case study takes a qualitative approach based on four semistructured focus group interviews carried out in May and June 2020 with 19 PACT members and leaders.

RESULTS

The case study illustrates that videoconferencing is a good solution for many persons with complex and long-term needs and generates new opportunities for interaction between patients and health care personnel. Persons with complex and long-term needs are a heterogeneous group, and for many patients with reduced cognitive capacity or hearing and vision impairment, the use of videoconferencing was challenging and required support from relatives or health care personnel. The study shows that using videoconferencing offered an opportunity to use health care personnel more efficiently, reduce travelling time for patients, and improve the information exchange between health care levels. This suggests that the integration of videoconferencing contributed to the preservation of the person-centered focus on care during the COVID-19 pandemic. There was an overall agreement in PACT that face-to-face care needed to be at the core of the person-centered care approach; the main use of videoconferencing was to support follow-up and coordination.

CONCLUSIONS

The COVID-19 pandemic and the rapid adoption of digital care have generated a unique opportunity to continue developing a health service to both preserve and improve the person-centered care approach for persons with complex and long-term needs. This creates demand for overall agreements, including guidelines and procedures for how and when to use videoconferencing to supplement face-to-face treatment and care. Implementing videoconferencing in clinical practice generates a need for systematic training and familiarization with the equipment and technology as well as for an extensive support organization. Videoconferencing can then contribute to better preparing health care services for future scenarios.
Labour Potential of the Arctic Regions of the European Russia
Authors: Shamakhov V. A. , Mezhevich N. M. , Romashkina Yu. V. , Tishkov S. V.
Published: October 2020

The work considered the possibilities and directions of evolution of demographic development of the Arctic region, analyzed some characteristics of the labor potential of the population living in the Arctic regions of the European part of Russia.

The purpose of the study is to substantiate the possibility of attracting the local population and the need to employment specialists from other regions of Russia for the development of the Arctic.

To achieve the goal of the study, general scientifi methods were used — the collection and analysis of data from state statistics and sample surveys. The use of a systematic approach made it possible to comprehensively assess the situation on the territory under study and substantiate the possibilities for its development.

Analysis of the quantitative characteristics of the labor potential of the studied regions showed a stable negative dynamics throughout the post-Soviet period. A number of reasons have been identifi  that contribute to the outfl   of population from the Arctic regions, the most important of which are the low standard of living compared to the Russian average, as well as the ineff     functioning of the mechanisms of northern guarantees and compensation. At the same time, the qualitative characteristics of labor potential, in particular, the level of education of the population can be increased due to the existing educational potential of neighboring regions.

Conclusions about the need to attract people from the regions of the middle zone of Russia for the Arctic are made.
El conflicto social por el acceso al agua: poder y producción de piña en Costa Rica
Authors: Bonilla-Bonilla Luis
Published: October 2020

La base de este artículo es una investigación realizada entre el 2017 y el 2018 desde la Cátedra de Sociología de la Escuela de Ciencias Sociales y Humanidades de la Universidad Estatal a Distancia (UNED). Uno de sus propósitos fue indagar dinámicas de conflicto sobre procesos de contaminación y acceso al agua potable en la zona atlántica y norte de Costa Rica, en determinados espacios territoriales en los cuales es notoria la interacción entre recurso hídrico, producción piñera y comunidades.
Complexity as new normality: What is going on?
Authors: Kálmán Anikó , Citterio Linda
Published: October 2020

In this paper we aim at presenting SEFI Annual Conference 2019 from the thematic point of view. Authors have creatively reacted to the main theme ‘Complexity as the new normality’ by targeting different areas of education where complexity arises: project work, curricular changes and connection to the job market are just few examples. The importance of soft skills alongside the core engineering background has motivated an intense discussion on the role of teaching in developing students’ skills. We identified the most represented topics at SEFI 2019 and we reflected on the importance of less represented topics such as Lifelong learning, Talent management, Sustainability and 4th Industrial Revolution. We based our decision on the relevance of such topics for shaping the future engineering education practices. We hope to spark the readers’ interest and motivate to explore the articles in this thematic issue as well as the Proceedings of SEFI 2019 Conference.
Which aspects of engineering degrees do graduates most value in their working lives?
Authors: Thomson Gareth
Published: October 2020

The creation and revision of degree programmes aims to build degrees with the correct blend of technical skills and competencies to ensure graduates are equipped to enter industry. While there may be data on first destinations of graduates there is often little follow up on how useful they felt their degree was in equipping them with the skills needed in industry. This study looks at the views of 32 graduates who graduated from a mechanical engineering programme over the last decade. Using both qualitative and quantitative methods it asks them to explore the impact of common degree features including project based learning, engineering science, dissertations and internships on their subsequent working lives. The study shows that while core knowledge and skills are still valued, authentic learning enabled by project based learning and internships are often at the heart of working graduates’ daily lives.
Classification of Abdominal CT Images bearing Liver Tumor Using Structural Similarity Index and Support Vector Machine
Authors: Siddiqi Ayesha Amir , Khawaja Attaullah , Hashmi Adnan
Published: October 2020

Computed Tomographic (CT) imaging is extensively implemented for liver tumor visualization and detection. Computer aided image processing algorithms can provide aid to the physicians and radiologists in detecting deadly diseases of liver specifically cancerous liver tumors. This paper presents a novel image processing technique to automatically classify liver for its abnormality without going through the liver segmentation stage. The study is conducted on a dataset of 39 samples of abdominal CT images. The CT dataset comprises of images bearing unhealthy liver. The unhealthy liver is further divided into livers bearing malignant tumors namely hepatoma and benign tumors namely hemangiomas. The methodology adopted for the study comprises of feature extraction from original CT images of all types of liver with special focus on textural information. The extracted features undergo the process of classification for malignancy and benignancy of the liver tumor. The classifiers used for textural feature analysis include Support Vector Machines (SVM), K-Nearest Neighbor (KNN) and ensemble classifier. Amongst these classifiers SVM yields a classification accuracy of 100% as compare to KNN and ensemble classifier which give the classification accuracy of 94.7% and 52.6% respectively. The proposed method of classification applied on entire abdominal CT scans without segmentation is performed by using the feature extraction matrix of structural similarity index (SSIM), which gives an improved classification accuracy of 100% as compared to the traditional GLCM matrix. The methodology can be tested to classify the liver for malignancy using other non-invasive techniques of ultrasounds and Magnetic Resonance Imaging (MRI) as well.
Effect of Fibers on the Bond Behavior of Deformed Steel Bar Embedded in Recycled Aggregate Concrete
Authors: Hameed Rashid , Akmal Usman , Khan Qasim S. , Cheema Muhammad Ahsan , Riaz Muhammad Rizwan
Published: October 2020

A large volume of concrete debris is being produced in many countries on the globe due to the demolition of old concrete structures and testing of concrete specimens in laboratories. One of the ways to reuse concrete debris is to produce Recycled Aggregates (RA) and use them in new concrete. In recent years, Recycled Aggregates Concrete (RAC) has experienced increasing demand in various non-structural and structural applications. In reinforced concrete structures, one of the sources of brittle failure is sudden loss of bond between reinforcing bars and concrete in anchorage zones. Therefore, for the structural application of any new kind of concrete such as fiber reinforced RAC, knowledge of bond characteristics of reinforcing bars embedded in concrete becomes essential for determining the overall structural response under different modes of loading. In this regard, this study experimentally investigated the effect of fibers on the bond stress-slip behavior of deformed steel re-bar embedded in RAC. Concrete mixes having 0, 50 and 100% RAs were prepared with and without the addition of fibers. Two types of fibers were investigated in mono form: hooked-ends steel and polypropylene fibers. The dosage of steel and polypropylene fibers was kept 40 and 4.4 kg/m3, respectively. Axial compression and standard pull-out tests were performed. Test specimens for pull-out test were prepared using deformed steel re-bars of 19mm (#6) diameter. The results of strength tests confirmed that the compressive strength of concrete is decreased by replacing Natural Aggregates (NA) with RAs. For bond behavior of steel re-bar, the results of this study showed that replacement of 50% NA with RAs did not affect the bond response of steel bar, however, 100% replacement of NA with RAs showed detrimental effect on bond stress slip behavior. The results further showed that the addition of both types of fibers made it possible to recover the loss in compressive strength, bond strengths and bond toughness occurred because of replacing NA with RAs. In case of RA concrete mixes containing hooked-ends steel fibers, strength values were found even greater than the strength values of Natural Aggregates Concrete (NAC). From the results of this study, it was found that it is possible to design a structural concrete mix using 100% RAs and steel fibers at relatively low dosage of 40kg/m3.
Experimental Study of Inclined Bridge Pier Scouring
Authors: Abbas Fakhar Muhammad , Naeem Usman Ali , Ghani Usman , Khan Amina , Ahmad Talat Farid
Published: October 2020

The bridges are one of important structures in any country. The failure of bridges occurs due to many factors including design flaws and manufacturing construction errors. Among all imperfections scouring around the pier is the most detrimental. So, the estimation of local scouring around a bridge pier is of fundamental importance for the safe design of bridges. Although numerous researches have been done on local scouring around a single bridge pier. The present study investigates the effect of angle of inclination of dual bridge pier configuration on local scouring around bridge piers. Principally rectangular shaped dual bridge piers were installed in sand bed of laboratory flume at angle of inclination of 0°,7°,12°,15° and 19° with vertical respectively. Three different flow rates 9, 14 and 18L/sec were considered during each trial. The duration of each trial was kept around 2 hours. The scour depth was measured separately around both piers with the help of point gauge under clear water condition. The value of scour depth around upstream pier was larger as compared to downstream pier because of the lower strength of horseshoe vortices around downstream pier. From the experimental results, it can be concluded that there is an inverse relationship between the angle of inclination and scour depth, an increase in the angle of inclination leads to decrease in scour depth around both piers. The value of scour depth was maximum when piers were at 0° and minimum at 19°. It was also found that scour depth increases with the increase in flow rate.
Is world trade slowing down? New evidence on trade-income elasticity
Authors: Altuzarra Amaia , Bustillo Ricardo , Rodríguez Carlos
Published: October 2020

This paper furthers and updates the research on the nature of the so-called global trade slowdown. Not only do we explain and discuss the determinants of this phenomenon, but we also offer an empirical description of the recent evolution of trade and trade elasticity. With the purpose of testing whether this is a structural phenomenon or not, we build an Error Correction Model for both world and regional data on trade and income using data from the World Bank for the period 1970-2017. World, OECD and Asian countries trade elasticity figures show a remarkable reduction after the hyperglobalization period (1986- 2001), opposed to those of Latin America where trade volume has not stagnated so much. This slowdown might have major consequences for any country, but especially for those which have relied more intensively on trade as an engine for growth.
Modeling and analysis of the impact of exothermic catalytic chemical reaction and viscous dissipation on natural convection flow driven along a curved surface
Authors: Ahmad Uzma , Ashraf Muhammad , Khan Ilyas , Nisar Kottakkaran
Published: October 2020

The impact of exothermic catalytic chemical reaction and viscous dissipation
on natural-convection heat transfer along the curved shape is investigated.
In this study, the trend of exothermic catalytic chemical reaction has been
introduced in the energy and mass concentration equation. Furthermore, the
tangential compo?nent of acceleration due to gravity, gx, as buoyancy force
has coupled in momentum equation describe the curved shape. The flow model
of the problem is formulated in terms of coupled non-linear PDE together
with suitable boundary conditions. From the numerical solutions of the
governing equations, it is found that velocity field, temperature
distribution and the mass concentration is associated with the dimensionless
parameters involved in the flow model. The novelty of the current study is
that the characteristics of heat and fluid-flow mechanism are specifically
associated with the different values of index parameter n.
Surface temperature and free-stream velocity oscillation effects on mixed convention slip flow from surface of a horizontal circular cylinder
Authors: Ullah Zia , Ashraf Muammad , Zia Saqib , Ali Ishtiaq
Published: October 2020

The present phenomena address the slip velocity effects on mixed convection
flow of electrically conducting fluid with surface temperature and free
stream velocity oscillation over a non-conducting horizontal cylinder. To
remove the difficulties in illustrating the coupled PDE, the primitive
variable formulation for finite dif?ference technique is proposed to
transform dimensionless equations into primitive form. The numerical
simulations of coupled non-dimensional equations are exam?ined in terms of
fluid slip velocity, temperature, and magnetic velocity which are used to
calculate the oscillating components of skin friction, heat transfer, and
cur?rent density for various emerging parameters magnetic force parameter,
?, mixed convection parameter, ?, magnetic Prandtl number, ?, Prandtl
number, and slip factor, SL. It is observed that the effect of slip flow on
the non-conducting cylinder is reduced the fluid motion. A minimum
oscillating behavior is noted in skin friction at each position but maximum
amplitude of oscillation in heat transfer is observed at each position ? =
?/4 and 2?/3. It is further noticed that a fluid velocity increas?es sharply
with the impact of slip factor on the fluid-flow mechanism. Moreover, due to
frictional forces with lower magnitude between viscous layers, the rise in
Prandtl number leads to decrease in skin fiction and heat transfer which is
physi?cally in good agreement.
Entanglement and geometric phase of the coherent field interacting with a three two-level atoms in the presence of non-linear terms
Authors: Hilal Eman , Alkhateeb Sadah , Abdel-Khalek Sayed , Khalil Eied , Almowalled Amjaad
Published: October 2020

We study the interaction of a three two-level atoms (3-2LA) with a one-mode
op?tical coherent field in coherent state in the presence of non-linear Kerr
medium. The three atoms are initially prepared in upper and entangled states
while the field mode is in a coherent state. The constants of motion, 3-2LA
and field density matrix are obtained. The analytic results are employed to
perform some investigations of the temporal evolution of the von Neumann
entropy as measure of the degree of entanglement between the 3-2LA and
optical coherent field. The effect of the detuning and the initial atomic
states on the evolution of geometric phase and en?tanglement is analyzed.
Also, we demonstrate the link between the geometric phase and non-classical
properties during the evolution time. Additionally the effect of detuning
and initial conditions on the Mandel parameter is studied. The obtained
results are emphasize the impact of the detuning and the initial atomic
states of the feature of the entanglement, geometric phase and photon
statistics of theoptical coherent field.
Goodness-of-fit tests for the beta Gompertz distribution
Authors: Abu-Zinadah Hanaa , Binkhamis Asmaa
Published: October 2020

This article studied the goodness-of-fit tests for the beta Gompertz
distribution with four parameters based on a complete sample. The parameters
were estimated by the maximum likelihood method. Critical values were found
by Monte Carlo simulation for the modified Kolmogorov-Smirnov,
Anderson-Darling, Cramer-von Mises, and Lilliefors test statistics. The
power of these test statistics founded the optimal alternative distribution.
Real data applications were used as examples for the goodness of fit tests.
Oldroyd-B nanofluid-flow between stretching disks with thermal slip and multiple flow features
Authors: Khan Ilyas , Ullah Khan , Chu Yu-Ming , Nisar Kottakkaran , Al-Khaled Kamel
Published: October 2020

This novel investigation deals with the thermal slip in magnetized
axi-symmetric flow of Oldroyd-B liquid configured by infinite stretchable
disks. With appliance of fundamental laws, the flow model equations are
constructed. The governing flow equations are altered into no-dimensional
form by using similarity quantities. The solution procedure is followed by
using famous homotopy analysis technique. The convergence analysis is
performed to evaluate the solution accuracy. The signifi?cance of flow
parameters in the pattern of velocity, temperature and concentration are
graphically illustrated. The novel numerical simulations for wall shear
stress, Nusselt number, and Sherwood number are also performed at both
surfaces of disks. It is noted the effects of relaxation time and
retardation constants on radial and normal velocity components is opposite.
The thermal slip parameters enhance the nanoparticles temperature. The
concentration profile is decreases with Brown?ian motion parameter.
A Jacobi wavelet collocation method for fractional fisher's equation in time
Authors: Secer Aydin , Cinar Melih
Published: October 2020

In this study, the Jacobi wavelet collocation method is studied to derive a
solution of the time-fractional Fisher?s equation in Caputo sense. Jacobi
wavelets can be considered as a generalization of the wavelets since the
Gegenbauer, and thus also Chebyshev and Legendre polynomials are a special
type of the Jacobi polynomials. So, more accurate and fast convergence
solutions can be possible for some kind of problems thanks to Jacobi
wavelets. After applying the proposed method to the considered equation and
discretizing the equation at the collocation points, an algebraic equation
system is derived and solving the equation system is quite sim?ple rather
than solving a non-linear PDE. The obtained values of our method are checked
against the other numerical and analytic solution of considered equation in
the literature and the results are visualized by using graphics and tables
so as to reveal whether the method is effectiveness or not. The obtained
results evince that the wavelet method is quite proper because of its simple
algorithm, high accuracy and less CPU time for solving the considered
equation.
Effect of nuclear magnetic distribution on thephoto production of longitudinally polarizedlepton-pairs in the field of Na2311 and Al2713 nuclei
Authors: Alkhateeb Sadah
Published: October 2020

In this work we treat the influence of the nuclear magnetic moment on the
photo production of e - e+, ?- ?+, ?- ?+ i. e. l- l+, lepton pairs. We
examine the process: ? + N(Ze, ?j ) ? N(Ze, ?j ) + l-(p- ) + l+(p+) of
production of (l- l+) - pairs by cir?cularly polarized photons ?(p?) in the
field of nucleus, N, having electric (coulomb) charge Ze, and magnetic
dipole moment ?j, where j is the nuclear spin. Taking into account the
longitudinal polarizations of the produced pairs, we calculate the
differential cross-sections for the angular and energy distributions of the
pair particles. We investigate the effect of the nuclear magnetic moment on
the angular and energy distribution of the antilepton l+(e+,?+,?+), showing
that the contribution the cross-section from the nuclear magnetic dipole
moment rises considerably on going to high energies of incident photon and
large emission angles of the pair particles. The results of calculations for
Na2311 (j =1/2) and Al2713 - target nuclei, and for the three lepton pair
types (e - e+, ?- ?+, ?- ?+) are presented graphically [1, 2].
Investigation the effect of sox emission reduction on transit ships emissions as of January 1, 2020
Authors: Tokuslu Aydin , Bayirhan Irsad , Gaziglu Cem
Published: October 2020

The Istanbul Strait is one of the choke points in the international maritime
trade. 44868 ships have passed through the Istanbul Strait in the last two
years. These merchant ships are emitting exhaust gas emissions such as CO2,
NOx, SOx inten?sively. These pollutants also affect human health and the
environment. There is a consensus among scientists that ambient
concentrations of particulate matter and SOx have negative health impacts,
including asthma, heart attacks, hospital admissions, and premature
mortality. In this study, the exhaust gas emissions from ships are estimated
based on real ship movements, and analyses are made accord?ing to the
reduction from 3.5-0.5% of the allowed sulphur content of the fuel was
implemented on January 1, 2020. Firstly, Annex four which is containing the
reg?ulations imposed by the International Maritime Organization was
examined, and also SOx emission which is caused by ships passing through the
Istanbul Strait was investigated. Also, a new approach to Trozzi and Vaccaro
methodology was built. After, emission projections for 2030 and 2040 were
made and the rate of SOx and particulate matter were analysed.
Influence of classical field on entanglement and photon statistics of n-level atom interacting with a two two-level atom
Authors: Alotaibi Hammad , Khalil Eied , Abdel-Khalek Sayed , Al-Barakaty Abdullah
Published: October 2020

In this study, we consider three interacting atoms, one of them represented
by N-level atom based on SU(2) Lie algebra and the other represented by a
two two-level atom in presence of the external field. The effect of the
external field on the dynamics of the proposed system is discussed in detail
for certain values for the external field. The dynamical expression of the
observable operators is obtained by using the Heisenberg equation of motion.
The general solution via solving Schrodinger equation is obtained. The
fidelity and concurrence formula as a measure of entanglement between two
two-level atom are calculated and discussed in detail. We explore the sudden
death and sudden birth phenomena with and without the presence of external
field. Finally, we compare the results of the fidelity, concurrence and
second-order correlation function for some values of the initial state and
the external field parameters.
New analytical solutions of heat transfer flow of clay-water base nanoparticles with the application of novel hybrid fractional derivative
Authors: Asjad Muhammad , Ikram Muhammad , Ali Rizwan , Baleanu Dumitru , Alshomrani Ali
Published: October 2020

Clay nanoparticles are hanging in three different based fluids (water,
kerosene, and engine oil). The exact terminologies of Maxwell-Garnett and
Brinkman for the current thermophysical properties of clay nanofluids are
used, while the flow occurrence is directed by a set linear PDE with
physical initial and boundary conditions. The classical governing equations
are extended to non-integer order hybrid fractional derivative which is
introduced in [33]. Analytical solutions for temperature and ve?locity
fields are attained via Laplace transform technique. Some limiting solutions
are also obtained from the existing literature and compared for different
values of fractional parameter. To vision the impact of several flow
parameters on the temperature and velocity some graphs are drawn using
Mathcad software and designed in different figures. As a result, we found
that hybrid fractional model is better in describing the decay behavior of
temperature and velocity in comparison of classical derivatives. In
comparison of nanofluid with different base fluids, it is concluded that
water-based nanofluid has higher velocity than others.
CD31+ Extracellular Vesicles From Patients With Type 2 Diabetes Shuttle a miRNA Signature Associated With Cardiovascular Complications
Authors: Prattichizzo Francesco , De Nigris Valeria , Sabbatinelli Jacopo , Giuliani Angelica , Castaño Carlos , Párrizas Marcelina , Crespo Isabel , Grimaldi Annalisa , Baranzini Nicolò , Spiga Rosangela , Mancuso Elettra , Rippo Maria Rita , Procopio Antonio Domenico , Novials Anna , Bonfigli Anna Rita , Garavelli Silvia , La Sala Lucia , Matarese Giuseppe , de Candia Paola , Olivieri Fabiola , Ceriello Antonio
Published: October 2020

Innovative biomarkers are needed to improve the management of patients with type 2 diabetes mellitus (T2DM). Blood circulating miRNAs have been proposed as a potential tool to detect T2DM complications, but the lack of tissue specificity, among other reasons, has hampered their translation to clinical settings. Extracellular vesicle (EV)-shuttled miRNAs have been proposed as an alternative approach. Here, we adapted an immunomagnetic bead–based method to isolate plasma CD31+ EVs to harvest vesicles deriving from tissues relevant for T2DM complications. Surface marker characterization showed that CD31+ EVs were also positive for a range of markers typical of both platelets and activated endothelial cells. After characterization, we quantified 11 candidate miRNAs associated with vascular performance and shuttled by CD31+ EVs in a large (n = 218) cross-sectional cohort of patients categorized as having T2DM without complications, having T2DM with complications, and control subjects. We found that 10 of the tested miRNAs are affected by T2DM, while the signature composed by miR-146a, -320a, -422a, and -451a efficiently identified T2DM patients with complications. Furthermore, another CD31+ EV-shuttled miRNA signature, i.e., miR-155, -320a, -342-3p, -376, and -422a, detected T2DM patients with a previous major adverse cardiovascular event. Many of these miRNAs significantly correlate with clinical variables held to play a key role in the development of complications. In addition, we show that CD31+ EVs from patients with T2DM are able to promote the expression of selected inflammatory mRNAs, i.e., CCL2, IL-1α, and TNFα, when administered to endothelial cells in vitro. Overall, these data suggest that the miRNA cargo of plasma CD31+ EVs is largely affected by T2DM and related complications, encouraging further research to explore the diagnostic potential and the functional role of these alterations.
White Rice Intake and Incident Diabetes: A Study of 132,373 Participants in 21 Countries
Authors: Bhavadharini Balaji , Mohan Viswanathan , Dehghan Mahshid , Rangarajan Sumathy , Swaminathan Sumathi , Rosengren Annika , Wielgosz Andreas , Avezum Alvaro , Lopez-Jaramillo Patricio , Lanas Fernando , Dans Antonio L , Yeates Karen , Poirier Paul , Chifamba Jephat , Alhabib Khalid F , Mohammadifard Noushin , Zatońska Katarzyna , Khatib Rasha , Keskinler Mirac Vural , Wei Li , Wang Chuangshi , Liu Xiaoyun , Iqbal Romaina , Yusuf Rita , Wentzel-Viljoen Edelweiss , Yusufali Afzal Hussein , Diaz Rafael , Keat NG Kien , Lakshmi PVM , Ismail Noorhassim , Gupta Rajeev , Palileo-Villanueva Lia M , Sheridan Patrick , Mente Andrew , Yusuf Salim
Published: October 2020

Objective:
Previous
prospective studies on association of white rice intake with incident diabetes
have shown contradictory results but were conducted in single countries and
predominantly in Asia. We report on the
association of white rice with risk of diabetes in the multinational
Prospective Urban Rural Epidemiology (PURE) study.

Research
design and methods: Data on
132,373 individuals aged 35-70 years, from 21 countries. were analysed. White rice
consumption (cooked) was categorised as <150, ≥150 to <300, ≥300 to
<450 and ≥450 grams/day, based on 1 cup of cooked rice = 150 grams. The
primary outcome was incident diabetes. Hazards ratios were calculated using
multivariable Cox frailty model.

Results: During
a mean follow up period of 9.5 years, 6,129 individuals without baseline
diabetes developed incident diabetes. In the overall cohort,
higher intake of white rice (≥450g/d compared with <150g/d) was
associated with increased risk of diabetes (HR: 1.20; 95% CI: 1.03-1.41 p for
trend=0.003). However, the highest risk
was seen in South Asia (HR: 1.65; 95% CI: 1.17-2.34, p for trend=0.02),
followed by other regions of the world (which included South East Asia, Middle
East, South America, North America/Europe and Africa) (HR: 1.41; 95% CI:
1.08-1.85, p for trend =0.01), while in China there was no significant
association (HR: 1.05; 95% CI: 0.78-1.41, p for trend = 0.38).

Conclusions:
Higher consumption
of white rice is associated with an increased risk of incident diabetes with the
strongest association being observed in South Asia, while in other regions, a
modest, non-significant association was seen.
Type 2 diabetes and COVID-19 related mortality in the critical care setting: A national cohort study in England, March-July 2020
Authors: Dennis John M. , Mateen Bilal A , Sonabend Raphael , Thomas Nicholas J , Patel Kashyap A , Hattersley Andrew T , Denaxas Spiros , McGovern Andrew P , Vollmer Sebastian J
Published: October 2020

Objective: To describe the relationship between type 2 diabetes and
all-cause mortality amongst adults with COVID-19 in the critical care setting.

Research Design and Methods: Nationwide retrospective
cohort study in people admitted to hospital in England with COVID-19 requiring
admission to a high dependency unit (HDU) or intensive care unit (ICU) between
March 1, 2020 and July 27, 2020. Cox proportional hazards models were used to
estimate 30 day in-hospital all-cause mortality associated with type 2
diabetes, adjusted for age, sex, ethnicity, obesity, and other major comorbidities
(chronic respiratory disease, asthma, chronic heart disease, hypertension,
immunosuppression, chronic neurological disease, chronic renal disease, and
chronic liver disease).

Results: 19,256 COVID-19 related HDU and ICU admissions were included
in the primary analysis, including 13,809 HDU (mean age 70), and 5,447 ICU
admissions (mean age 58). 3,524 (18.3%) had type 2 diabetes. 5,077 people (26.4%)
died during the study period. People with type 2 diabetes were at increased
risk of death (adjusted hazard ratio (aHR) 1.23 [95%CI 1.14;1.32]), results
were consistent in HDU and ICU subsets. The relative mortality risk associated
with type 2 diabetes decreased with increasing age (age 18-49 aHR 1.50 [95%CI 1.05;2.15];
age 50-64 1.29 [1.10;1.51]; age 65 or greater 1.18 [1.09;1.29], p-value for age:type
2 diabetes interaction 0.002).

Conclusions:
Type 2 diabetes may be an independent prognostic
factor for survival in people with severe COVID-19 requiring critical care
treatment, and in this setting the risk increase associated with type 2
diabetes is greatest in younger people.
Slozhnosti differentsial'noy diagnostiki kozhnykh proyavleniy pri koronavirusnoy infektsii.
Authors: Таирова Р. Т. , Гайдина Т. А. , Дворников А. С. , Тазартукова А. Д. , Лянг О. В.
Published: October 2020

Pri lechenii mul'timorbidnykh patsiyentov s tyazhelym techeniyem novoy koronavirusnoy infektsii, vyzvannoy virusom SARS-CoV-2 (COVID-19), neobkhodimo proyavlyat' vnimaniye k vozmozhnomu razvitiyu lekarstvennoy ekzantemy (LE) v lyuboy period vremeni lecheniya. Predstavleno klinicheskoye nablyudeniye bol'noy 92 let s tyazhelym techeniyem podtverzhdennogo PTSR SOVID-19. Na fone lecheniya amoksitsillinom/klavulanovoy kislotoy, moksifloksatsinom, atsetiltsisteinom, omeprazolom, enoksaparinom natriya na 9-y den' lecheniya poyavilis' umerenno zudyashchiye makuleznyye vysypaniya s tendentsiyey k sliyaniyu bez otritsatel'noy dinamiki somaticheskogo statusa. Na 15-y den' lecheniya na fone priyema deksametazona i khloropiramina kozhnyye vysypaniya regressirovali. Poyavleniye sypi mozhet byt' obuslovleno primeneniyem b-laktamnykh antibakterial'nykh preparatov i ftorkhinolonov, prisoyedineniyem bakterial'noy infektsii i immunnosupressivnym statusom patsiyentki starcheskogo vozrasta, a takzhe vysokoy virusnoy nagruzkoy, assotsiirovannoy s poyavleniyem dermatologicheskikh simptomov. Otsrochennoye poyavleniye kozhnykh izmeneniy na fone COVID-19 vozmozhno rassmatrivat' kak «marker» tyazhesti zabolevaniya.
(ARTICLE RETRACTED) The Relation of Gender and Feminism in Islamic Jurisprudence
Authors: Wasitaatmadja Fokky Fuad , Susianto Susianto , Supendi Suartini
Published: October 2020

This article is RETRACTED, because has been publish before at Center for Open in Science (COAS) Open Journal for Legal Studies (OJLS) on Vol. 3 No. 2, 2020. if you want to read and cite this article, please visit http://centerprode.com/ojls/ojls0302/coas.ojls.0302.04125w.html
Géographies symboliques
Authors:   Université Babeș-Bolyai, Cluj-Napoca, Roumanie (corinbraga@yahoo.com), Braga Corin
Published: October 2020

Over the past few decades, cultural studies have embraced concepts and methodologies set forth by the new fields of inquiry brought about by the “spatial turn”. These new disciplines combine knowledge from the domains of geography and literature in an interdisciplinary way. In my paper I propose to go beyond this dialogue between disciplines to the roots of both geographical and literary representations, that is, I aim to discuss the geographical imaginary. Resorting to concepts from the theory of fictional worlds, I will make a distinction between “realistic” or “mimetic” geographies, “symbolic” geographies, “fictional geographies”, and “allegorical” geographies. I am primarily interested in symbolic geographies and the non-empirical criteria which produced, especially during ancient, medieval and early modern times, cartographical and literary representations of the world that might appear to be fantastical nowadays, but that were nonetheless considered adequate in their respective epoch
The Geography Factor: Image as Localization, History as Place
Authors:   Babeş-Bolyai University, Cluj-Napoca, Romania (horea.avram@gmail.com), Avram Horea
Published: October 2020

The paper explores the ability of a number of recent 3D mapping platforms and visualization systems (such as Photosynth 2, Mapillary, Streetmuseum and History Pin) to produce a different spatial and perceptual paradigm, one that merges reality and virtuality, past-tense and live experience, local and global. This type of visual experience, highly dependent on the “geography factor,” is what I call “image as localization.” I will demonstrate how the latter redefines in a profound manner the very definition of image and, in the process, the conceptualization of place and participation.