bluuebunny/crossref_metadata_2025 huggingface dataset:
Gastroenterology visitation and reminders predict surveillance uptake for patients with adenomas with high-risk features
Authors: Myint Anthony , Corona Edgar , Yang Liu , Nguyen Bao Sean , Lin Christina , Huang Marcela Zhou , Shao Paul , Mwengela Didi , Didero Michelle , Asokan Ishan , Bui Alex A. T. , Hsu William , Maehara Cleo , Naini Bita V. , Kang Yuna , Bastani Roshan , May Folasade P.
Published: April 2021

Individuals diagnosed with colorectal adenomas with high-risk features during screening colonoscopy have increased risk for the development of subsequent adenomas and colorectal cancer. While US guidelines recommend surveillance colonoscopy at 3 years in this high-risk population, surveillance uptake is suboptimal. To inform future interventions to improve surveillance uptake, we sought to assess surveillance rates and identify facilitators of uptake in a large integrated health system. We utilized a cohort of patients with a diagnosis of ≥ 1 tubular adenoma (TA) with high-risk features (TA ≥ 1 cm, TA with villous features, TA with high-grade dysplasia, or ≥ 3 TA of any size) on colonoscopy between 2013 and 2016. Surveillance colonoscopy completion within 3.5 years of diagnosis of an adenoma with high-risk features was our primary outcome. We evaluated surveillance uptake over time and utilized logistic regression to detect factors associated with completion of surveillance colonoscopy. The final cohort was comprised of 405 patients. 172 (42.5%) patients successfully completed surveillance colonoscopy by 3.5 years. Use of a patient reminder (telephone, electronic message, or letter) for due surveillance (adjusted odds = 1.9; 95%CI = 1.2–2.8) and having ≥ 1 gastroenterology (GI) visit after diagnosis of an adenoma with high-risk features (adjusted odds = 2.6; 95%CI = 1.6–4.2) significantly predicted surveillance colonoscopy completion at 3.5 years. For patients diagnosed with adenomas with high-risk features, surveillance colonoscopy uptake is suboptimal and frequently occurs after the 3-year surveillance recommendation. Patient reminders and visitation with GI after index colonoscopy are associated with timely surveillance completion. Our findings highlight potential health system interventions to increase timely surveillance uptake for patients diagnosed with adenomas with high-risk features.
Several frailty parameters highly prevalent in middle age (50–65) are independent predictors of adverse events
Authors: Segaux Lauriane , Broussier Amaury , Oubaya Nadia , Leissing-Desprez Claire , Laurent Marie , Naga Henri , Fromentin Isabelle , David Jean-Philippe , Bastuji-Garin Sylvie
Published: April 2021

Although frailty can arise in middle age, very few studies have investigated frailty before 65 years. Our objectives were to assess the prevalence of frailty parameters in middle-aged individuals and probe the association with future adverse events. We performed cross-sectional and longitudinal analyses of community-dwelling individuals aged 50 to 65 (n = 411, median age: 59.0) having undergone a multidomain geriatric assessment (2010–2015) in an outpatient clinic in the greater Paris area of France (SUCCEED cohort). The primary outcome was a composite measure of adverse events (non-accidental falls, fractures, unplanned hospitalizations, death), recorded in 2016/2017. Multivariable logistic regression models were built to identify independent predictors. Six frailty parameters were highly prevalent (> 20%): low activity (40.1%), exhaustion (31.3%), living alone (28.5%), balance impairment (26.8%), weakness (26.7%), and executive dysfunction (23.2%). Female sex (odds ratio: 2.67 [95% confidence interval: 1.17–6.11]), living alone (2.39 [1.32–4.33]), balance impairment (2.09 [1.16–3.78]), executive dysfunction (2.61, [1.18–5.77]), and exhaustion (2.98 [1.65–5.39]) were independent predictors of adverse events. Many frailty parameters are already altered in middle-aged individuals and are predictive of adverse health events. Our findings highlight a possible need for frailty screening and preventive programs targeting middle-aged individuals.
Author Correction: Grain boundary oxidation of proton-irradiated nuclear grade stainless steel in simulated primary water of pressurized water reactor
Authors: Deng Ping , Peng Qunjia , Han En-Hou
Published: April 2021

An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Ultrathin polymethylmethacrylate interlayers boost performance of hybrid tin halide perovskite solar cells
Authors: Ding Dong , Lanzetta Luis , Liang Xinxing , Min Ganghong , Giza Marcin , Macdonald Thomas J. , Haque Saif A.
Published: April 2021

Introducing a polymethylmethacrylate (PMMA) layer at the (PEA)0.2(FA)0.8SnI3 perovskite/hole transport layer interface leads to a remarkable improvement in the photogenerated current density and fill factor, resulting in an increase in the power conversion efficiency from 6.5% to 10%.
Characterising and communicating the potential hazard posed by potentially toxic elements in indoor dusts from schools across Lagos, Nigeria
Authors: Famuyiwa Abimbola O. , Entwistle Jane A.
Published: April 2021

PTEs measured in Lagos indoor dusts were higher than those reported from other Nigerian cities, and suggest PTE build up in recent years. However, the calculated risks factors were within acceptable limits for both children and adults.