bluuebunny/crossref_metadata_2025 huggingface dataset:
Co-gasification of Waste Biomass and Plastic for Syngas Production with CO2 Capture and Utilization: Thermodynamic Investigation
Authors: Srav Pathipaka , Povari Sangeetha , Alam Shadab , Nakka Lingaiah , Srin Surananai , Chenna Sumana
Published: May 2023

This work presents an integrated plant-wide process for co-gasification of waste biomass and plastics using steam and CO2 to produce an industrially important feed stock i.e., syngas with molar ratio of H2/CO ~ 2. The proposed plant wide process is designed with key feature of carbon capture and utilization (CCU) and made self-sustainable by utilizing a fraction of syngas for meeting the heat, steam and CO2 demands with additional heat recovery and steam generation and power generation sections. Further, steady state plant wide models are developed using ASPEN Plus, and simulations are performed for the co-gasification of high-density polyethylene (HDPE) and rice husk (RH) at varying feed compositions (0-100% HDPE). Further, rigorous sequential parametric sensitivity analysis is performed to determine the optimal process parameters and investigate the impact of feed composition on the product yield. Results revealed that steam to carbon ratio (S/C) should be maintained above 1.2 to attain complete carbon conversion within the gasifier which tends to enhance the overall performance of the integrated scheme. The comparative investigation on co-gasification of HDPE and RH revealed that an increase in weight percentage of HDPE in the feed mixture resulted in increased syngas production and plant efficiency due to the high carbon and low ash content of HDPE. Gasification of pure HDPE waste resulted in the maximum output of 2.2 kg of syngas/kg of feed with a net plant efficiency of 68%, while in the case of pure RH the syngas production and efficiency dropped to 0.60 kg/kg of feed and 35%, respectively.
Firm size and pro-environmental behavior in Cameroon
Authors: Juliot Mpabe Bodjongo Mathieu , Fofana Moustapha , Kabwe Omoyi epse Essomme Fanny
Published: May 2023

Previous studies indicate a lack of analysis of pro-environmental behavior adoption in enterprises of various sizes. Very small enterprises, especially in the informal sector, have always been overlooked in the literature, although they are in the majority in most countries. This paper aims to examine the effects of firm size on pro-environmental behavior adoption in Cameroon. The analysis focuses on a sample of 141,926 firms drawn from the Second General Census of Enterprises (RGE-2) in Cameroon (NIS, 2018). The study adopted a statistical and econometrical approach based on the logit model. The results showed that the adoption of pro-environmental behavior increases with firm size. The probability of having a health, safety, and environment system increases by 16.70 points in large enterprises compared to 8.40 points in small enterprises. The probability of having a wastewater management system increases by 5.30 points in large enterprises compared to 2.30 points in small enterprises. The probability of having an air pollution management system increases by 2.20 points in large enterprises compared to 1.50 points in small enterprises. However, company size does not significantly influence the adoption of a solid waste management system. It is recommended to (i) raise awareness among large companies of the challenges of environmental protection and to strengthen controls on compliance with environmental standards, and (ii) to implement actions aimed at the migration of companies from the informal to the formal sector.
Determinants of consumer purchasing behavior toward Korean cosmetic products: Evidence from Indonesia
Authors: Widayat Widayat , Azis Noor , Maya Kumala Sari Herlinda , Warsono Warsono , Masudin Ilyas
Published: May 2023

Korean cosmetics have become a favorite product in the Indonesian market. Therefore, it is essential to understand what stimulates Indonesian consumers to buy Korean beauty products. This study aims to examine the structural model of the determinants of purchasing behavior for cosmetic products made in Korea, applying a quantitative design. Data were collected using a questionnaire targeting a random sample of respondents (n = 250) who are social media followers of cosmetic products made in Korea. The collected data were then analyzed using a partial least square approach using Smart-PLS 4.0 software. The results indicate that consumer attitude significantly influences consumer behavior. Moreover, the findings imply that a positive attitude can build consumer behavior (make consumers proud and idolize a particular product). Furthermore, the positive image of the place of origin and the quality of the product can influence consumer attitude. Management practice can alter how individuals view a product by using brand ambassadors and the rich culture of the place the product comes from.
Adaptation of internally displaced persons in host communities under conditions of war in Ukraine: The role of local governments
Authors: Voznyak Halyna , Mulska Olha , Druhov Oleksiy , Patytska Khrystyna , Sorokovyi Danylo
Published: May 2023

The aggravation of the migration crisis in the country against the background of socio-economic instability in conditions of war has triggered the deterioration of the institutional and economic capacity of local governments to ensure further integration of internally displaced persons in the host society. The article aims to identify the resource and economic capacity of local governments in conditions of war to ensure the needs and adaptation of internally displaced persons to new living conditions (using the example of Pidberiztsivska Territorial Community of Lvivska Oblast). The research is based on a questionnaire survey in the form of in-depth interviews with the representatives of local governments. The sample consists of 20 persons; strata are formed in accordance with the staff units of local governments (head of the village council; representatives of the community’s administrative center and starostyn districts; heads of structural units of the village council). The paper emphasizes that local governments face a great challenge in ensuring the adaptation of internally displaced persons in the community, mainly related to the lack of free housing (according to 76.2% of respondents) and the labor surplus in the local market (over 20%). The results show that the majority of internally displaced persons see the community only as a place of “waiting” and seek to return to the former residence place (68.4% of the interviewed representatives of local government), so they shouldn’t be deemed as a potential community asset. Proactive tools for increasing the resource and economic capacity of local governments to ensure further integration of internally displaced persons include interaction with regional authorities, efficient use of the capacity of relocated businesses, cooperation with charitable foundations and NGOs to solve housing problems and create additional high-wage jobs.
Building creativity in the television industry: The mediating role of meaning of work
Authors: Hidayat Syamsul , Eliyana Anis , Setia Pratama Andika , Permana Emur Alvin , Kresna Nugraha Bayu
Published: May 2023

Creative human resources are becoming urgent amidst development in recent decades. The television industry has been one that faces the challenge with the emergence of new platforms offering variety and ease of information. Hence this study aims to test the direct effect of perceived organizational support on employee creativity and the mediation role of the meaning of work. This study was conducted on Net Mediatama Television, a private television company, specifically among employees working in the content department, since this division constantly needs creativity to develop concepts and create a broadcast program. Data from 70 respondents were collected through online questionnaires and analyzed with the PLS technique. The results confirmed that perceived organizational support and meaning of work are relevant factors that directly stimulate and enhance employee creativity. The mediating role of work meaning for perceived organizational support and creativity was also proven significant. This indicates that employees who get organizational support have a strong meaning towards work so that their level of creativity increases. Based on these findings, organizations can formulate strategic steps to increase employee creativity by focusing on organizational support and meaningfulness in work.
The Impact of Social Influence, Product Knowledge, and Fear of Missing Out (FOMO) towards Purchase Intention on Alcoholic Beverage in Bali
Authors: Dwisuardinata Ida Bagus Nyoman , Darma Gede Sri
Published: May 2023

Based on the enactment of official government regulations in Governor Regulation No. 1 of 2020 concerning the Governance of Balinese Fermented and Distilled Drinks, arak Bali has started to appear publicly. It brings many advantages for the Balinese, especially in the business of fermented drink production. However, it is still unknown about consumer behavior regarding the interest in arak Bali, especially among Balinese people who live socially. The research aimed to determine the effect of social influence, product knowledge, and Fear of Missing Out (FOMO) on purchase intention in arak Bali. The population used was millennials and Generation Z in Denpasar City who had looked for information and consumed arak Bali. The amount of sample used was 153 respondents. Then, data analysis model  used  the Structural Equation Model (SEM) with AMOS 24. Based on the results of data processing with AMOS 24, it can be concluded that there is a significant and positive effect of social influence on purchase intention, product knowledge on purchase intention, social influence on FOMO, and product knowledge on FOMO. Meanwhile, FOMO has no significant but positive effect on purchase intention. It is known that the effect of product knowledge on purchase intention has the greatest influence and value in the research.
Indonesian Stand-Up Comedy: A New Developing Industry of Youth Culture
Authors: Sihombing Lambok Hermanto , Rahma Fajri Annisa , Divia Sonali Mita , Lestari Puji
Published: May 2023

The research analyzed the growth of stand-up comedy in Indonesia, which had developed into a new trend or popular culture and a new creative business that produced skilled and well-known comics. Furthermore, it discussed how stand-up comedy might develop into a new creative business by evaluating the growth of the community, Instagram, and YouTube, as well as the growth of successful comics. In order to help the researchers doing the analysis, the researchers applied a qualitative method. They used two theories named Self-presentation concept by Goffman and Creative Industry theory by Richard Florida. The findings indicate that the creative industry does not always progress forward; interest in stand-up comedy decreased in various places, but it is still attempting to develop. Indonesian people are becoming more receptive to stand-up comedy as it is home to some of the world's most talented comics. Comics must be innovative in their approach to content creation to increase their popularity and viability. Apart from that, when comics are popular, they can inspire others to pursue careers as comics. As a result, comics members continue to grow in number, the community grows in size, and the creative business continues to flourish. Stand-up comedy has developed into popular culture and a new creative sector geared toward youth.
Design and modeling of vertical tube evaporator in a thermal-driven multiple effect distillation system
Authors: Chandra Pravesh , Mudgal Anurag , Patel Jatin
Published: May 2023

The scarcity of freshwater is one of the biggest issues in the world, as a result of which more attention is given to the thermal distillation process for seawater and as well as brackish water distillation which removes almost all types of contaminants. Multiple effect distillation makes the process economical by recycling the latent heat of vaporization. In this paper a vertical tube evaporator is designed for a small scale thermal driven MED system comprising six effects and one condenser and a boiler that can produce 20–25 kg/hr of steam. VTE dimensions are calculated by estimating the outside diameter for different configurations. Heat transfer coefficient was estimated by using the developed correlations of the Bell method, Kandlikar and Kutateladze, compared with previous experiments and then used for calculating the heat transfer area for different distillate flow rates. An appropriate vertical tube evaporator is designed with the developed model to condense 25–30 kg/hr steam for producing 50–75 lt/hr freshwater. The result shows good agreement with previous work and reliability in design. The Developed model can also be used to design the vertical tube evaporator for different sizes (micro scale to large scale) MED plant.
ZE SPUŚCIZNY PROFESORA CEZAREGO KUNDEREWICZA. TRUDNA DROGA DO AKADEMII
Authors: Pikulska-Radomska Anna
Published: May 2023

Profesor Cezary Kunderewicz (1912-1990) był wybitnym romanistą, papirologiem, znawcą praw klinowych i szeroko rozumianej kultury antycznej. Dokumenty pochodzące z jego prywatnego archiwum, w połączeniu z archiwaliami Uniwersytetów: Warszawskiego i Łódzkiego, pozwalają na odtworzenie trudności, jakie musiał pokonać osiągając kolejne etapy rozwoju naukowego.
NABIERANIE MOCY WIĄŻĄCEJ PRZEZ „SOFT LAW”
Authors: Chrostek Jakub
Published: May 2023

Tematem artykułu jest nabieranie mocy wiążącej przez sof law. Natomiast celem artykułu jest identyfikacja oraz ocena sposobów nabierania przez miękkie prawo mocy wiążącej. W problemie badawczym zdefiniowano pytanie: Jak miękkie prawo nabiera mocy wiążącej? Soft law rozumiane jako swoiste zobowiązanie polityczne często okazuje się równie skuteczne, jak normy typu hard law. Niewątpliwie na taki stan rzeczy wpływa aspekt, że miękkie prawo w ujęciu międzynarodowym posiada tendencję do tzw. twardnienia. W wyniku przeprowadzonej analizy wnioskuję, że soft law nabiera mocy wiążącej poprzez wolę stron lub praktykę w podejściu do materii regulowanej miękkim prawem. Proces twardnienia soft law zachodzi w szczególności w dwóch wymiarach. Po pierwsze, kiedy przyjęcie aktu prawa miękkiego jest pierwszym krokiem w procesie zawarcia wiążącego aktu prawa międzynarodowego, w którym to akcie następuje odwoływanie się do zasad oraz standardów zawartych w poprzedzających go źródłach prawa miękkiego. Po drugie, akty prawa miękkiego mogą zmienić bądź wpłynąć na dotychczasową praktykę w taki sposób, by przełożyć się na powstanie nowego prawa zwyczajowego w ujęciu międzynarodowym. Soft law może również stanowić wzór dla ustawodawstwa krajowego, a tym samym stać się regulacją prawnie wiążącą wewnętrznie, pozostając prawem miękkim na arenie międzynarodowej.
Juicios intersubjetivos. Algunas similitudes en Kant, Smith y Arendt
Authors: Alegria Daniela
Published: May 2023

En este artículo me centraré en las posibles similitudes entre la estructura del juicio estético de la Crítica de la facultad de juzgar (1790) de Kant y la estructura del juicio moral en La teoría de los sentimientos morales (1759) de Adam Smith. Hannah Arendt en sus Conferencias sobre la filosofía política de Kant (1970) toma la estructura del juicio estético kantiano y la aplica en el ámbito de la política, para que surja una dimensión moral como consecuencia (i.e. Arendt busca regular la acción política con alcances morales). Analizaré la estructura del juicio estético kantiano e indagaré las similitudes que tiene éste con la estructura del juicio moral smithiano, con el fin de examinar hasta qué punto Smith ayudaría a ampliar y profundizar el proyecto filosófico de Arendt. Pareciera ser que Smith está cerca del proyecto arendtiano. Propondré que la estructura del juicio estético kantiano, el juicio político arendtiano y el juicio moral smithiano son todos juicios intersubjetivos, es decir, son juicios que necesitan contrastarse con los otros. Los tres juicios juzgan lo particular desde la mirada de un espectador imparcial gracias a la facultad de la imaginación.
Escepticismo y razón práctica en la filosofía de J. G. Fichte
Authors: Corsico Luciano
Published: May 2023

En el presente trabajo, mi objetivo es analizar los argumentos que utiliza J. G. Fichte en su refutación del escepticismo de E.G. Schulze y de S. Maimon. Mi hipótesis principal es que Fichte puede obtener un criterio racional satisfactorio para refutar al escepticismo, en la medida en que adopta la perspectiva de un primado de la razón práctica. La conexión entre la refutación del escepticismo y el primado de la razón práctica resulta mucho más evidente en los primeros escritos publicados por Fichte durante el período de Jena (1794-1799). En cierto sentido, la duda escéptica está basada en una actitud meramente teórica o contemplativa. Sin embargo, la filosofía de Fichte demuestra que existe en el hombre una tendencia originaria a la acción y a la transformación de la realidad según leyes racionales. El sujeto experimenta la realidad a través de un sentimiento provocado por algo que ofrece resistencia a su tendencia práctica y por lo tanto no puede mantener su actitud escéptica sin contradicción.
La verdad y su fundamento en Tomás de Aquino: reflexiones en torno a Martin Heidegger y Xavier Zubiri
Authors: Mayne-Nicholls Michael Anthony
Published: May 2023

En el presente artículo se estudia la noción de verdad de Tomás de Aquino en torno a otras dos concepciones que han sido fundamentales en la historia de la filosofía, como son las de Martin Heidegger y Xavier Zubiri, identificando las principales diferencias entre estos autores, así como posibles puntos de encuentro, tarea que será desarrollada teniendo en consideración una interrogante central: ¿son, en algún sentido, compatibles estas nociones de verdad? Con el fin de encontrar su respuesta, se procurará establecer cuál es el fundamento último que cada uno reconoce para esta.
The Correlation between Age, Fat Intake, and Visceral Fat and Body Mass Index at the Gym
Authors: Kadir Sunarto , Mokodompis Yasir
Published: May 2023

Background:

This study aimed to investigate the correlation between age, fat intake, visceral fat, and body mass index (BMI) of gym members.

Methods:

A cross-sectional approach was employed with a sample of 87 respondents. Primary data were obtained from three different gyms, while secondary data was obtained from gym owners. A questionnaire was used as the research instrument, and the Chi Square test was used for data analysis.

Results:

The majority of respondents had a higher fat intake than recommended, and most had high levels of visceral fat. In terms of BMI, the majority were classified as either overweight or obese. Bivariate analysis showed significant correlations between age, fat intake, and visceral fat with BMI among gym members.

Conclusion:

This study found that age, fat intake, and visceral fat were significantly correlated with BMI among gym members. The findings suggest the importance of promoting healthy dietary habits and exercise among gym members, particularly those older or with high visceral fat levels.
How the good corporate governance moderate relationship between corporate social responsibility voluntary disclosure and firm value?
Authors: Dewi Ni Gusti Ayu Made Utari , Widanaputra Anak Agung Gde Putu
Published: May 2023

This study aims to obtain empirical evidence regarding the effect of Good Corporate Governance, which is proxied by managerial ownership, institutional ownership, the proportion of independent commissioners, and audit committees as a moderating variable on the relationship between disclosure of Corporate Social Responsibility and the value of banking companies listed on the IDX for the period 2019-2021. This research includes quantitative descriptive research. The population in this study are all banks listed on the Indonesia Stock Exchange (IDX). The sampling technique used was purposive sampling technique and the samples obtained were 31 banks. Tobin's Q is used as a ratio in measuring firm value. The type of data used is secondary data derived from the company's annual report and sustainability report. The data were analysed by descriptive analysis and multiple regression analysis. The results showed that Good Corporate Governance (GCG) as a moderating variable significantly influences the relationship between Corporate Social Responsibility (CSR) and firm value. This means that banks that disclose higher Corporate Social Responsibility (CSR) can increase firm value, especially in companies with a level of implementation of Good Corporate Governance (GCG) which is proxied by high managerial ownership in banking companies listed on the IDX for 2019-2021.
Planificación del cultivo: selección, adecuación y producción de semillas
Authors: Cardona William Andrés , Bolaños Benavides Martha Marina , Rodríguez Blandón Jefersson Andrés , Ospina Parra Carlos Eduardo , Machuca Henao Yuly Marcela
Published: May 2023

Tipos de semilla de plátano para el establecimiento del cultivo de plátano se pueden utilizar los anteriores tipos de semilla.
Manejo integrado de artrópodos plaga: monitoreo y manejo de otros artrópodos plagas
Authors: Bautista Montealegre Luis Gabriel , Betancourt Vásquez Mónica , Rodríguez Blandón Jefersson Andrés , Rodríguez Yzquierdo Gustavo Adolfo , Miranda Salas Tatiana Camila
Published: May 2023

Monitoreo: Recorridos en los lotes en zigzag, “X” o “W” semanal o quincenalmente. Evaluar aleatoriamente daños causados por la plaga en 10 % de las plantas establecidas. Registrar en planillas o cuadernillos las plagas observadas.
Componente ambiental: pasturas (Magathyrsus maximus cv. Agrosavia Sabanera)
Authors: Mejía Kerguelén Sergio Luis , Atencio Solano Liliana Margarita , Tapia Coronado José Jaime , Suárez Paternina Emiro Andrés
Published: May 2023

Gramínea forrajera con adaptación a las condiciones de la región Caribe de Colombia.
Manejo integrado de enfermedades: reconocimiento y manejo de elefantiasis
Authors: Betancourt Vásquez Mónica , Bautista Montealegre Luis Gabriel , Rodríguez Yzquierdo Gustavo Adolfo , Miranda Salas Tatiana Camila , Rodríguez Blandón Jefersson Andrés
Published: May 2023

Disturbio común en zona cafetera desde la década de los años 60; sin embargo, en los últimos años (2010 - 2021) se ha registrado mayor incidencia, con pérdidas importantes en cultivos de banano y plátano.
Manejo fitosanitario: Phythoptora
Authors: Rochel Ortega Elizabeth , Rodríguez Blandón Jefersson Andrés , Suárez Villota Pedro David , Castillo Jorge Andrés , Jaimes Suárez Yeirme Yaneth
Published: May 2023

En frutos, los primeros síntomas se presentan como pequeñas manchas de color oscuro sobre los tejidos. Los signos aparecen de tres a cinco días después de los primeros síntomas. Aparición de esporangios y un micelio pulverulento blanco.
Modelo de producción sostenible de carne bovina para el Caribe húmedo
Authors: Mejía Kerguelén Sergio Luis , Suárez Paternina Emiro Andrés , Atencio Solano Liliana Margarita , Tapia Coronado Jose Jaime
Published: May 2023

El sistema intensivo de producción de carne de buena calidad procura establecerse de manera orgánica o ecológica y sus componentes ambientales, sociales, de bienestar animal y aspecto económico son los pilares fundamentales. Los principales beneficios son: 1. Reducción de emisiones de gases de efecto invernadero, favorecido por el uso de árboles, arbustos y variabilidad de especies (Mejía et al. 2019). 2. Resurgimiento de especies, como árboles, arbustos, arvenses, leguminosas nativas, micro, meso y macroorganismos que van a interactuar con las pasturas y los bovinos, para formar un sistema sostenible de producción. 3. Reciclaje de nutrientes, por el aporte de residuos vegetales, raíces muertas, hojas maduras, ramas, flores y frutos que caen al suelo, provenientes de los árboles, arbustos, pastura y arvenses presentes en el modelo.
Crecimiento económico del Estado de México ante el cambio en la estrategia de desarrollo, 1981-2021
Authors: Mejía-Reyes Pablo , Albarrán Macías Dulce , Rendón Rojas Liliana
Published: May 2023

El objetivo de este documento es analizar los efectos de la producción del resto del país, la manufactura estatal y la de Estados Unidos como principales factores de demanda sobre el crecimiento del producto del Estado de México durante el periodo 1981-2020. Mediante la estimación de modelos econométricos con cambio estructural, los resultados sugieren que las primeras dos tienen un efecto estable y positivo y creciente pero moderado, respectivamente,  mientras que la última tuvo uno negativo antes de mediados de los años noventa y uno positivo a partir de entonces, como consecuencia de la integración internacional de este estado.
Physical and Nutritional Properties of Analog Rice Based on Modified Cassava Flour and Modified Suweg Flour
Authors: Hasbullah Umar Hafidz Asy'ari , Surayya Latifatus , Syah Ikrar Taruna
Published: May 2023

Analog rice can be developed from modified cassava flour (MOCAF) and modified Suweg (Amorphophallus campanulatus) flour (MSF). This research aims to study the physical and nutritional characteristics of analog rice made from a combination of MOCAF and MSF. Analog rice was formulated from both flour with MOCAF: MSF ratios (w/w), among others (100: 0), (90: 10), (80:20), (70:30), (60:40), and (50:50). The dough was printed in an extruder and dried so that it becomes analog rice. The results showed that changes in the MOCAF: MSF ratio cause significant changes to the physical characteristics and nutrients of analog rice. Interestingly, the increasing amount of MSF in the formulation causes the weight of one hundred grains, bulk density, protein, water, ash, and crude fiber in analog rice to rise. However, water absorption, color brightness, fat, and carbohydrates in analog rice was fell 54%, 17%, 23%, 4%, respectively. Therefore, analog rice produced from MOCAF and MSF can be a source of food to maintain the nation's food security.
Hidup dalam Ketidakpastian: Strategi Pedagang Pantai Pulang Sawal dalam Menggapai Resiliensi pada Masa Pandemi Covid-19
Authors: Yuda Oki Oktami , Sushartami Wiwik
Published: May 2023

Penelitian ini berangkat dari fakta bahwa pandemi COVID-19 memberikan dampak yang negatif bagi kehidupan manusia di berbagai sektor. Pantai Pulang Sawal merupakan salah satu destinasi wisata yang terkena dampak secara tidak langsung dari pandemi COVID-19. Dampak yang ditimbulkan menyentuh para pedagang yang hidupnya sangat bergantung pada operasional pariwisata. Artikel ini bertujuan untuk mengetahui bagaimana strategi yang dilakukan oleh para pedagang di pantai Pulang Sawal dalam menggapai resiliensi di tengah masa pandemi COVID-19. Selanjutnya, untuk melihat hubungan antara strategi yang telah para pedagang lakukan dengan berbagai kemungkinan kendala yang akan mempengaruhi kualitas resiliensi mereka. Penelitian fenomenologis dilakukan dengan wawancara semi terstruktur dengan pedagang makanan dan minuman. Hasil penelitian ini menunjukan bahwa para pedagang melakukan serangkaian strategi adaptasi untuk dapat bertahan. Dari strategi yang telah dilakukan oleh para pedagang pada kenyataannya tidak dapat memecahkan masalah yang mereka hadapi. Terdapat kondisi tak terduga diluar jangkauan yang dapat para pedagang lakukan. Pada akhirnya para pedagang mengalami kerentanan secara ekonomi. Dampak kerentanan ekonomi yang berjenjang membuat mereka juga mengalami kerentanan secara sosial dan budaya.
Complex aestheticss treatment of six maxillary anterior teeth with smile design and deep bite correction
Authors: Nugraheni Tunjung , Yulianasari Yulianasari , Octarina Lia Desire
Published: May 2023

Dental trauma mostly damages the maxillary anterior teeth, affecting the individual’s esthetics, functionality, and psychological well-being. Restorative dentistry treatment is required to obtain a natural appearance based on the smile design approach. The aim of this report is to characterize the procedure of complicated cosmetic restoration of the six maxillary anterior teeth, which results in straighter and more beautiful natural-looking smiles. A 32-year-old male patient presented with multiple crown fractures in the anterior maxillary teeth, resulting in an unaesthetics smile. The patient also had a deep bite. A comprehensive aesthetics dental treatment was carried out. The dental treatment plan had to be carefully executed by considering several factors such as dental convexities and contours, re‑establishment of function, and esthetics. Smile design should always be approached as a multi-factor decision-making, which enables the doctor to treat patients using a personalized and interdisciplinary approach.
Implementasi Crowdsourcing di Perpustakaan dalam Pembuatan Produk Kemas Ulang Informasi
Authors: Susianti Vivi Aprillia
Published: May 2023

Crowdsourcing merupakan tren terbaru dalam perpustakaan. crowdsourcing merupakan konsep yang berkaitan dengan partisipasi masyarakat tanpa melihat latar belakang dan agama untuk menyelesaikan suatu proyek atau kegiatan dengan tujuan tertentu. Di Indonesia sudah banyak yang menggunakan konsep crowdsourcing terutama komunitas dalam menggalang donasi untuk mencapai tujuan tertentu. Konsep crowdsourcing dapat digunakan oleh perusahaan, institusi maupun komunitas. Perpustakaan umum merupakan Lembaga nirlaba yang dapat menggunakan konsep crowdsourcing untuk menyelesaikan sebuah proyek atau kegiatan perpustakaan untuk mencapai tujuan tertentu. Tulisan ini akan membahas bagaimana konsep crowdsourcing dapat diimplementasikan di perpustakaan khususnya dalam pembuatan produk kemas ulang informasi. Sebagaimana perpustakaan diketahui sebagai Lembaga yang memberikan layanan kepada pengguna sesuai dengan kebutuhan informasi pengguna. Oleh karena itu untuk menarik pengguna maka perpustakaan berinovasi pada layanan perpustakaan salah satunya yaitu membuat produk kemas ulang informasi berupa video animasi dan komik sebagai media pembelajaran. Kegiatan tersebut perpustakaan menggunakan konsep crowdsourcing untuk mendapatkan desain maskot kartun dan pembuatan komik.
Tren Layanan Perpustakaan Saat dan Pasca Pandemi Covid-19
Authors: Adirati Melania
Published: May 2023

Perpustakaan menghadapi berbagai tantangan akibat pandemi Covid-19 dengan beberapa kali merombak sistem pelayanannya. Pertama perpustakaan dipaksa menutup layanan, sehingga perpustakaan mengubah keseluruhan layanan tradisional ke layanan online. Saat ini muncul layanan hybrid dengan tetap menjaga protokol kesehatan. Kondisi yang masih tidak stabil ini mengharuskan perpustakaan memikirkan solusi jangka panjang terhadap layanan perpustakaan kedepan, sampai pada kondisi pandemi berakhir. Penelitian ini bertujuan untuk menggali informasi dan pemahaman terkait tren layanan perpustakaan selama dan pasca pandemi Covid-19. Metode penelitian yang digunakan adalah studi literatur dengan mengumpulkan dan menganalisis berbagai sumber literatur terkait tren layanan perpustakaan seperti apa yang berkembang selama pandemi hingga pasca pandemi Covid-19. Hasil penelitian menunjukkan bahwa perpustakaan dapat mengadopsi teknologi pintar, seperti AR, VR, IoT, dan Gaming. Penggunaan teknologi tersebut dimaksudkan untuk meringankan pekerjaan pustakawan, memudahkan pengguna mengakses layanan perpustakaan, serta memberikan pengalaman baru bagi pengguna sehingga menarik minat kunjungan. Kesimpulan dari penelitian ini adalah dalam memberikan pelayanan perpustakaan harus selalu mampu menyesuaikan dengan kebutuhan pengguna sehingga sebaiknya bergerak mengikuti tren-tren baru yang sedang berkembang saat ini agar tetap eksis.
CLINICO-RADIOLOGICAL FEATURES IN CORROBORATION WITH INTRAOPERATIVE FINDINGS OF INTUSSUSCEPTION IN INFANTS-LESSONS LEARNED FROM CASES SERIES IN REMOTE SET UP DURING OVERSEAS DEPLOYMENT (EAST AFRICA)
Authors: YADAV NARENDER , HIREMATH RAVISHEKAR N , DHAGAT PEEYUSH , LEELAKANTH KASUKURTHI , RAJ RISHI
Published: May 2023

The incidence rate of Intussusception is higher in some developing countries, which leads to a higher rate of complications in those areas especially in children. Plain abdomen radiograph is the initial radiological examination to be done in a case of acute abdomen in a peripheral set up. Ultrasound (USG) would be best modality for initial screening even in remote areas as it has the advantages of being non-invasive, rapid, and not only cost effective but also avoids radiation exposure and easily available even in peripheral set up in today’s era. Moreover, can be done bedside, even with less experienced readers. Here, in this case series, we are discussing the clinic-radiological and intraoperative features of in intussusception in infants, while we were deployed in remote areas of Eastern Africa with limited settings. This article highlights the importance of strong clinical suspicion and timely ultrasonographic evaluation as primary screening modality in suspected cases of intussusception. USG not only confirms the diagnosis with classical signs and appearances but also help rule out other conditions mimicking the diagnosis and will decrease the risk for bowel obstruction, perforation, necrosis, and death by aiding in timely surgical intervention. In addition to this, the lesson learned from this case series is that, assessment of length of segment of bowel telescoping into the other segment will aid in deciding mode of surgical intervention.
NEUROPROTECTIVE EFFECT OF ABELMOSCHUS ESCULENTUS ON CHRONIC STRESS AND EVALUATION OF LOSS OF MEMORY, ADAPTOGENIC EFFECT
Authors: CHENOLY SHABINA KOMATH , C SHANKARAPPA , PINNELLI VENKATA BHARATKUMAR
Published: May 2023

Objective: Objective of this study was to determine if there was any neuroprotective effect of Abelmoschus esculentus L and its role in preventing memory loss during stressful conditions.
Methods: The powder of A. esculentus L. pods was extracted with methanol and was used for evaluating anti-stress activity in experimental mice groups. The five experimental mice groups, namely, control, stress control, animals treated with extract followed by exposure to stress, animals exposed to stress followed by extract treatment, and mice groups treated with diazepam was evaluated. Biomarkers included were cortisol, brain homogenate acetylcholine esterase (AchE), superoxide dismutase (SOD), and malondialdehyde (MDA). In conjugation, working memory and reference memory were also studied in all animal groups by radial arm maze test, and results were recorded as the percentage of alteration score (PAS).
Results: The concentration of stress indicators such as cortisol, MDA, and AchE activity was significantly elevated in stress control animals and associated with deficit working and reference memory. However, SOD was reduced in stressed mice and increased in treatment groups compared to the control mice. The anti-stress activity of A. esculentus L. pods was significantly correlated with higher working memory and reference memory with 1.33±0.51 and 1.17±0.40 PAS in pre-stress and post-stress treated mice groups, respectively.
Conclusion: Methanolic extract of A. esculentus L. pods revealed the excellent anti-stress potential and also played a significant role in enhancing both working memory and reference memory in mice.
XANTHOGRANULOMATOUS APPENDICITIS-A RARE HISTOLOGICAL VARIANT
Authors: MITTAL MOHIT , HIREMATH RAVISHEKAR N , GAUR NIMISH , VERMA VISHAL , GHODKE SANDHYA
Published: May 2023

Xanthogranulomatous inflammation (XGI) is a chronic inflammatory process most commonly described in the case of gall bladder and kidney. The same occurring in the case of the vermiform appendix is a rare occurrence. Here, we describe two cases of appendicitis in which postoperatively histopathological examination revealed typical features of XGI in the appendix.
TOPICAL FORMULATION CONSTITUTED WITH TRANSFEROSOMES FOR THE TREATMENT OF NON-MELANOMA SKIN CANCER
Authors: IMAM SYED SAIF
Published: May 2023

Overexposure to UV-B radiation causes an evolution in the strands of DNA of skin membrane cells, resulting in non-melanoma skin cancer. With the addition of excipients and nanovesicular structures such as transferosomes that boost the permeability rate and pharmacological activity, a formulation containing curcumin, kaempferol, trans-resveratrol, and apigenin have been developed which possess strong anti-inflammatory and anti-proliferative potential. The formulation quickly penetrates the stratum corneum and acts on cancer cells, inhibiting metastasis and angiogenesis by interfering with signaling molecules in the three primary mitogen-activated protein kinase pathways: extracellular-signal-regulated kinase, c-Jun N-terminal kinases, and p38. It blocks pro-inflammatory cytokines such as lipopolysaccharide, tumor necrosis factor-alpha, IL1, IL6, COX-2, LOX, oxidative stress, and lowers the levels of matrix metalloproteinase (MMP)-3, MMP-9, and vascular endothelial growth factor. The yield value, sensory testing, spreadibility, dynamic viscosity, water content, pH, specific gravity, anti-microbial preservative concentration, microbiological limit, sterility testing, contaminants, uniformity of dosage, and assay on RAW264.7 cell line will all be used to evaluate the formulation. The O/W cream that has been produced will be significantly more successful than traditional cancer treatments, and it will have no side effects, protects the patient from recurrence of cancer and inexpensive treatment.
COMPARISON BETWEEN THORACIC EPIDURAL AND PARAVERTEBRAL BLOCK TECHNIQUE FOR POSTOPERATIVE ANALGESIA IN THORACOTOMY
Authors: SUNDARI MANTHA RADHA , RAMESH VOMMI VENKATA , GKV Satyanarayana
Published: May 2023

Objectives: The present study was planned to compare paravertebral block with conventional thoracic epidural technique in terms of efficacy, duration of analgesia, and complications in patients undergoing thoracotomy.
Methods: A prospective randomized, double-blinded control study was conducted at King George Hospital adults undergoing thoracotomy between January 2020 and June 2021 after getting permission from the institutional ethical committee and getting consent from the patient. Patients were allocated into two groups by simple random sampling: Group A – patients receiving thoracic epidural anesthesia and Group B – patients receiving paravertebral blocks. The total sample size of the study was 32. Under strictly controlled aseptic conditions, a Tuohy needle was inserted in the midline of the thorax, and the epidural space was verified using the loss of resistance technique. The catheter was secured after being inserted via the needle. The surgeon in Group B inserted a Tuohy needle into the paravertebral space under direct view after the procedure.
Results: The age distribution of study subjects in both the groups was similar, and only a minor difference was observed. The difference in mean age between the two groups was not statistically significant (p>0.05); hence, both the groups were comparable. There was a statistically significant difference between the mean MAP between the two groups throughout the postoperative period. There was a statistically significant variation in mean value of in the mean arterial pressure over time as p<0.05. However, this variation in MAP was minimal in subjects who received paravertebral block compared to a statistically significant drop in MAP among subjects who received epidural block. This difference in MAP variation between the two groups was statistically significant. The minor difference in mean PEFR between the two groups was not statistically significant (p>0.05); hence, both the groups were comparable regarding PEFR.
Conclusion: From the present study, TPVA and TEA are helpful for pain relief, and the technique selection should depend on the patient profile, clinical scenario, and expertise of the anesthesiologist in the regional approach available.
CLINICAL PROFILE OF CHILDREN WITH FEBRILE SEIZURE IN A TEACHING HOSPITAL
Authors: PRIYANISHABEN DHODI , KHAN ZUBAIR , Patil Pushparaj
Published: May 2023

Objectives: To find out the clinical feature and outcomes of febrile seizures.
Methods: After written informed consent, detailed clinical history of each patient including a time of presentation, the onset of fever and associated symptoms, data regarding demographic details, duration and type of seizure, history of seizures, and antiepileptic drug, repetition of seizure within 24 h, past history of seizures, birth history, family history was taken and entered in predesigned pro forma. Collected data were checked and verified for correctness and accuracy, which was then analyzed using statistical methods.
Results: In the present study male-to-female ratio was 1.75:1. The maximum number (82.5%) of patients lacked a family history of febrile seizure, while 17.5% of patients had a positive family history of FS. 70% of the pediatric patients had upper respiratory tract infection. The maximum number of patients had simple febrile seizures, which are 81.25%, whereas 18.75% of patients had complex febrile seizures. The majority (73.75%) of patients in the present study had anemia. WBC count >11×109/L was found in 45 patients out of 80 (56.25%), and WBC count<4.5×109/L was found in 6 out of 80 (7.5%).
Conclusion: Majority of patients with febrile seizures presented at a younger age which might represent the vulnerability of the developing brain to fever. As all the patients were discharged without any complication, so this study further adds to the knowledge of the benign nature of this disease.
DETERMINATION AND SIMULTANEOUSLY QUANTIFICATION OF FIVE ORGANIC VOLATILE IMPURITIES USING HEAD SPACE GAS CHROMATOGRAPHY IN LEVOCLOPERASTINE FENDIZOATE ACTIVE PHARMACEUTICAL INGREDIENTS AND DOSAGE FORMS
Authors: Vidyamani Uppalapati , RAMACHANDRAN DITTAKAVI
Published: May 2023

Objectives: Organic chemical solvents are generally used during drug material synthesis, excipients, as well as in the drug product formulation. They are not acceptable in the finished product. Hence, the main objective of our work is development and validation of rapid, sensitive, and selective head space gas chromatography (GC-HS) method for the determination of five organic volatile impurities (OVI) (methanol, ethanol, dichloromethane, toluene, and benzene) in Levocloperastine Fendizoate active pharmaceutical ingredient (API) and commercial syrups.
Methods: The method was developed using a thermal gradient elution program associated with a column having dimensions are ZB-624, 30 m × 0.53 mm × 3.0 μm with a flow rate of 3.0 mL/min and Nitrogen (N2) as a carrier gas. A flame ionization detector was used as a detector, and its temperature is at 250°C whereas the injector temperature is at 225°C. The total run time is 25.0 min.
Results: The newly developed GC-HS method was validated by its specificity and selectivity system precision, and method precision, limit of detection and limit of quantification, linearity, accuracy, robustness, ruggedness, and solution stability as per International Council for Harmonization (ICH). Quantization limits for five impurities were 210 ppm for methanol, 350 ppm for ethanol, 42 ppm for dichloromethane, 62 ppm for toluene, and 0.4 ppm for benzene. Correlation coefficient values of linearity were higher than 0.995 for five OVI. The mean recoveries of five impurities were between 90% and 110%.
Conclusion: We found good and accepted results as per ICH guidelines for all validated parameters for five OVI. Thus, the developed GC-HS method was suitable for the separation and quantification of five OVI in Levocloperastine Fendizoate API and commercial syrups at present.
SLC66 Lysosomal amino acid transporters in GtoPdb v.2023.1
Authors: Gyimesi Gergely , Hediger Matthias A.
Published: May 2023

This is a family of 5 evolutionarily related proteins. Their structural similarities suggest that they are transporters. Biochemical evidence supports transporter activity for SLC66A1 (LAAT1) and SLC66A4 (CTNS; Cystinosin), primarily exporting amino acids from the lysosome to the cytoplasm. The functions of the 3 remaining members of the family are undetermined.
Taste 2 receptors in GtoPdb v.2023.1
Authors: Behrens Maik
Published: May 2023

Taste 2 receptors or Bitter taste receptors (TAS2Rs) are G protein-coupled receptors expressed in oral sensory cells and a variety of non-gustatory tissues. The ~25 human TAS2Rs share low amino acid sequence identities with other GPCR families and are classified as broadly tuned "generalist" receptors with numerous, chemically diverse bitter agonists, as narrowly tuned "specialist" receptors with very few activators, as intermediately tuned receptors with an average number of agonists, or receptors specialized to interact with chemically defined activators [32]. The number of functional bitter taste receptor genes varies among species and orthologues might not be functionally conserved. Due to their expression in various tissues, the signal transduction of TAS2Rs is complex. Some TAS2Rs interact with drugs such as analgesic, anti-inflammatory, and antibacterial compounds. The specialist database BitterDB contains additional information on bitter compounds and receptors [14].
SLC1 family of amino acid transporters in GtoPdb v.2023.1
Authors: Beart Philip M.
Published: May 2023

The SLC1 family of sodium dependent transporters includes the plasma membrane located glutamate transporters and the neutral amino acid transporters ASCT1 and ASCT2 [3, 52, 39, 40, 9].
ABCC subfamily in GtoPdb v.2023.1
Authors: Vore Mary
Published: May 2023

Subfamily ABCC contains thirteen members and nine of these transporters are referred to as the Multidrug Resistance Proteins (MRPs). The MRP proteins are found throughout nature and they mediate many important functions. They are known to be involved in ion transport, toxin secretion, and signal transduction [7, 2].
ABCD subfamily of peroxisomal ABC transporters in GtoPdb v.2023.1
Authors: Kemp Stephan
Published: May 2023

Peroxisomes are indispensable organelles in higher eukaryotes. They are essential for the oxidation of a wide variety of metabolites, which include: saturated, monounsaturated and polyunsaturated fatty acids, branched-chain fatty acids, bile acids and dicarboxylic acids [5]. However, the peroxisomal membrane forms an impermeable barrier to these metabolites. The mammalian peroxisomal membrane harbours three ATP-binding cassette (ABC) half-transporters, named ABCD1, -2 and -3. The ABCD transporters predominantly act as homodimers to transport different acyl-CoAs.
Adenosine turnover in GtoPdb v.2023.1
Authors: Boison Detlev
Published: May 2023

A multifunctional, ubiquitous molecule, adenosine acts at cell-surface G protein-coupled receptors, as well as numerous enzymes, including protein kinases and adenylyl cyclase. Extracellular adenosine is thought to be produced either by export or by metabolism, predominantly through ecto-5’-nucleotidase activity (also producing inorganic phosphate). It is inactivated either by extracellular metabolism via adenosine deaminase (also producing ammonia) or, following uptake by nucleoside transporters, via adenosine deaminase or adenosine kinase (requiring ATP as co-substrate). Intracellular adenosine may be produced by cytosolic 5’-nucleotidases or through S-adenosylhomocysteine hydrolase (also producing L-homocysteine).
Hydrogen sulphide synthesis in GtoPdb v.2023.1
Authors: Billiar Timothy R. , Cirino Giuseppe , Fulton David , Motterlini Roberto , Papapetropoulos Andreas , Szabo Csaba
Published: May 2023

Hydrogen sulfide is a gasotransmitter, with similarities to nitric oxide and carbon monoxide. Although the enzymes indicated below have multiple enzymatic activities, the focus here is the generation of hydrogen sulphide (H2S) and the enzymatic characteristics are described accordingly. Cystathionine β-synthase (CBS) and cystathionine γ-lyase (CSE) are pyridoxal phosphate (PLP)-dependent enzymes. 3-mercaptopyruvate sulfurtransferase (3-MPST) functions to generate H2S; only CAT is PLP-dependent, while 3-MPST is not. Thus, this third pathway is sometimes referred to as PLP-independent. CBS and CSE are predominantly cytosolic enzymes, while 3-MPST is found both in the cytosol and the mitochondria. For an authoritative review on the pharmacological modulation of H2S levels, see Szabo and Papapetropoulos, 2017 [8].