bluuebunny/crossref_metadata_2025 huggingface dataset:
Fibroma em mucosa jugal: uma revisão de literatura
Authors: Cunha Leticiane de Araújo , Souza Pâmela Tenazor de , Silva Sarah Evellyn Pinto da , Pessoa Karolinne Dantas , Fonseca Tiago Silva da , Silva Alenildo Pereira da
Published: November 2024

O fibroma traumático é a lesão mais comum entre os tumores benignos na cavidade oral. Objetiva-se revisar a literatura científica sobre fibroma em mucosa jugal. Histologia mostra tecido conjuntivo colagenizado e denso, ocasionalmente frouxo. Para tanto procede-se à revisão de literatura nas bases PubMed, Scielo e Google Scholar com termos “fibroma traumático”, “mucosa jugal” e “tratamento cirúrgico”. Seleção de artigos dos últimos 10 anos sobre patologia, diagnóstico e tratamento do fibroma traumático. Exclusão de casos isolados e revisões não sistemáticas. Análise qualitativa dos dados para identificar padrões e novas abordagens terapêuticas. O que permite concluir que o tratamento é simples: excisão cirúrgica e remoção do fator irritante causal para evitar recidiva. Apesar do diagnóstico e tratamento fáceis, é importante continuar estudando o fibroma traumático para manter e difundir conhecimento científico de qualidade na odontologia.
Transição epidemiológica em idosos no Brasil: análise de tendência temporal da mortalidade por acidente vascular cerebral no período de 2011 a 2021
Authors: Santos José Victor Dantas dos , Souza Laura Oliveira Silva e , Martins Gustavo Henrique Almeida , Sátiro Vitória Leitão Marins
Published: November 2024

O Acidente Vascular Cerebral (AVC) é uma das principais causas de morbidade e mortalidade, especialmente entre os idosos. No Brasil, o AVC é responsável por uma elevada taxa de óbitos nessa população. Este trabalho objetiva avaliar a tendência dos índices de mortalidade por AVC em idosos no Brasil entre 2011 e 2021, considerando o crescimento populacional estratificado por faixas etárias. Este estudo ecológico utilizou dados do Sistema de Informações Hospitalares do SUS (SIH/SUS), disponíveis no Departamento de Informática do SUS (DATASUS). Foram analisados casos notificados de óbitos por AVC em idosos, com estratificação por faixas etárias: 60-69, 70-79 e 80 anos ou mais. Os índices de mortalidade foram calculados por 100.000 habitantes e comparados com a variação populacional de idosos, segundo o IBGE. Entre 2011 e 2021, foram registrados 200.779 óbitos por AVC em idosos. Na faixa de 60-69 anos, o índice de mortalidade caiu 8%, enquanto a população cresceu 44%. Entre 70-79 anos, a mortalidade reduziu 10%, com um aumento populacional de 43%. Para idosos com 80 anos ou mais, a mortalidade diminuiu 15%, apesar de um crescimento populacional de 49%. Esses dados refletem a transição demográfica no Brasil, com aumento da população idosa. O estudo evidencia um declínio significativo nos índices de mortalidade por AVC, especialmente entre os idosos com 80 anos ou mais.
Detection of Hg
2+
Using a Dual-Mode Biosensing Probe Constructed Using Ratiometric Fluorescent Copper Nanoclusters@Zirconia Metal-Organic Framework/
N
-Methyl Mesoporphyrin IX and Colorimetry G-Quadruplex/Hemin Peroxidase-Mimicking G-Quadruplex DNAzyme
Authors: Jain Shikha , Nehra Monika , Dilbaghi Neeraj , Chaudhary Ganga Ram , Kumar Sandeep
Published: November 2024

Mercury (Hg
2+
) has been recognized as a global pollutant with a toxic, mobile, and persistent nature. It adversely affects the ecosystem and human health. Already developed biosensors for Hg
2+
detection majorly suffer from poor sensitivity and specificity. Herein, a colorimetric/fluorimetric dual-mode sensing approach is designed for the quantitative detection of Hg
2+
. This novel sensing approach utilizes nanofluorophores, i.e., fluorescent copper nanoclusters-doped zirconia metal-organic framework (CuNCs@Zr-MOF) nanoconjugate (blue color) and
N
-methyl mesoporphyrin IX (NMM) (red color) in combination with peroxidase-mimicking G-quadruplex DNAzyme (PMDNAzyme). In the presence of Hg
2+
, dabcyl conjugated complementary DNA with T–T mismatches form the stable duplex with the CuNCs@Zr-MOF@G-quadruplex structure through T–Hg
2+
–T base pairing. It causes the quenching of fluorescence of CuNCs@Zr-MOF (463 nm) due to the Förster resonance energy transfer (FRET) system. Moreover, the G-quadruplex (G4) structure of the aptamer enhances the fluorescence emission of NMM (610 nm). Besides this, the peroxidase-like activity of G4/hemin DNAzyme offers the colorimetric detection of Hg
2+
. The formation of duplex with PMDNAzyme increases the catalytic activity. This novel biosensing probe quantitatively detected Hg
2+
using both fluorimetry and colorimetry approaches with a low detection limit of 0.59 and 36.3 nM, respectively. It was also observed that the presence of interfering metal ions in case of real aqueous samples does not affect the performance of this novel biosensing probe. These findings confirm the considerable potential of the proposed biosensing probe to screen the concentration of Hg
2+
in aquatic products.
Circulating Interleukin-6 Mediates PM
2.5
-Induced Ovarian Injury by Suppressing the PPARγ Pathway
Authors: Chen Yingying , Zhang Jinjin , Zhang Tianyu , Wu Yaling , Xi Yueyue , Wu Tong , Li Mo , Li Yan , Zhou Su , Wu Mingfu , Wang Shixuan
Published: November 2024

Exposure to airborne fine particulate matter (PM
2.5
) is strongly associated with poor fertility and ovarian damage. However, the mechanism underlying this remains largely unclear. Here, we found that PM
2.5
markedly impaired murine ovarian reserve, decreased hormone levels, and aggravated ovarian inflammation. Circulating interleukin-6 (IL-6) was elevated in PM
2.5
-exposed mice and was further confirmed to mediate this damage by IL-6 recombinant protein intervention. PM
2.5
exposure led to increased alveolar macrophage infiltration in the lungs. However, alveolar macrophage clearance with clodronate liposomes could not fully reverse the elevated IL-6 levels and ovarian injury, suggesting that alveolar macrophages were probably not the only source of circulating IL-6. Further experiments indicated that IL-6 mainly targeted ovarian theca–interstitial cells and impaired testosterone synthesis via suppressing the peroxisome proliferator-activated receptor γ (PPARγ) pathway. In addition, apoptosis of granulosa cells and restriction of follicular growth were observed in co-cultures with IL-6-treated theca–interstitial cells, which could be further reversed by the PPARγ agonist. Moreover, IL-6-neutralizing antibodies ameliorated PM
2.5
-induced ovarian damage. Notably, increased levels of circulating IL-6 were observed in premature ovarian aging patients and were inversely associated with their ovarian function. In summary, our findings offer a mechanistic explanation for PM
2.5
-induced ovarian dysfunction and verify IL-6 as a biomarker and potential therapeutic target.
Evaluating the Prevalence and Prognostic Factors in Children With Scorpion Sting
Authors: Rahmati Mohammad Bagher , Azad Mohsen , Mehrabi Maryam
Published: November 2024

Objectives: Scorpion stings are a major public health problem in many countries and several parts of Iran, especially in Hormozgan Province. This study aimed to evaluate the prevalence and the effect of several variables on the prognosis of scorpion stings. Methods: This retrospective study was conducted on 606 patients admitted to Bandar Abbas Children’s Hospital, Bandar Abbas Port, Iran, from April 2014 to November 2017. We used a checklist to collect data about scorpionism. Results: Of 606 people who participated in the survey, 55.1% were males and 44.9% were female. The scorpion sting cases mainly occurred in the summer (38.9%) and spring (29.9%). Also, 61.9% were from rural areas. In addition, 68.6% of stings were seen in exposed extremities, 30.9% happened in the morning, and 75% of patients were referred to the hospital after 3 hours. Discussion: Hormozgan province is a significant economic area, and most scorpion sting cases occur in summer and spring. The development of medical knowledge and the availability of antivenom are essential indicators to control the outcome of scorpion stings.
Reflections on the Health System Impact Fellowship and the Future of Embedded Research Comment on "Early Career Outcomes of Embedded Research Fellows: An Analysis of the Health System Impact Fellowship Program"
Authors: Lopatina Elena , Singal Deepa , Manhas Kiran Pohar
Published: November 2024

The Health System Impact (HSI) Fellowship program in Canada offers a transformative approach to health services and policy research (HSPR) training, preparing PhD graduates for diverse career pathways and leadership roles within learning health systems. This commentary builds on Kasaai and colleagues’ evaluation of the HSI Fellowship to discuss the diverse career paths of alumni and highlight the multifaceted benefits of the program. Further, we emphasize the need for future research and knowledge mobilization to better understand and evaluate embedded research roles. Developing a robust evaluation framework is essential to capture the unique impacts of embedded research, fostering a culture that prioritizes and integrates it, thereby driving the transformation towards learning health systems.
Can’t Contracting Be Relational? Comment on "Alignment in the Hospital-Physician Relationship: A Qualitative Multiple Case Study of Medical Specialist Enterprises in the Netherlands"
Authors: Hughes David
Published: November 2024

Ubels and van Raaij provide a valuable account of the operation of novel hospital/medical specialist enterprise (MSE) contracts in a Dutch healthcare system shaped by market reform. However, their analytical distinction between the separate domains of contractual and relational governance frames the contractual domain more narrowly than does the relational contract theory widely deployed in socio-legal studies. The authors’ conclusion that contract plays little or no part in governing relations between hospitals and MSEs leads them to underplay a wider realm of contractual practices that develop in the shadow of the written contract. Apparent non-use of contracts in favour of shared planning, compromise and extra-legal solutions only takes the form it does because of the potential application of the available legal framework. Larger qualitative field studies involving a more extensive combination of interviews and observations may be needed to gain fuller insights into the relational dimensions of the contracting process.
Confronting the Colonial Roots of Global Health Inequities in Gaza Comment on "The Rhetoric of Decolonizing Global Health Fails to Address the Reality of Settler Colonialism: Gaza as a Case in Point"
Authors: Veronese Guido , Kagee Ashraf , Abu Jamei Yasser
Published: November 2024

This response critically examines the editorial by Engebretsen and Baker, emphasizing the colonial underpinnings of global health as it pertains to Gaza. We argue that global health is not merely ineffective but complicit in perpetuating settler colonial structures that exacerbate health disparities. The health crisis in Gaza is intricately linked to Israeli occupation, challenging the reductionist frames of "conflict health" and "refugee health" often employed by global health institutions. The presence of non-governmental organizations (NGOs) in Gaza exemplifies how international health efforts can depoliticize the crisis, as they often operate within constraints that do not challenge the underlying power dynamics. Our call for localization and self-determination highlights the complexities of achieving these goals in a context where the state is unrecognized. To effect meaningful change, global health must confront and dismantle the colonial structures underpinning health inequities in Gaza, moving beyond superficial humanitarian approaches to advocate for justice and autonomy.
TÜRKİYE-İRAN İLİŞKİLERİNDE DÖNÜM NOKTASI: İRAN ŞAHI RIZA PEHLEVİ’NİN TÜRKİYE ZİYARETİNİN AKŞAM GAZETESİNDE YANSIMALARI
Authors: Kadıoğlu Ahmet Murat
Published: November 2024

Türkiye Cumhuriyeti’nin 1923 yılında kurulmasının ardından Türkiye’de başlayan modernleşme çabaları sınır ülkelerine de örnek olmuştur. Türkiye ile İran arasında gergin geçen ilişkilerden sonra İran Şahı Rıza Pehlevi’nin Türkiye’yi ziyareti iki ülke arasında dostluğun pekişmesine yol açmıştır. Pehlevi, İran’da başa geçtikten sonra Mustafa Kemal Atatürk ve kurduğu yeni cumhuriyet rejimini örnek almış ve İran’da Türkiye’de olduğu gibi modern bir rejim kurmayı amaçlamıştır. Bu bakımdan Pehlevi’nin ziyareti Türkiye’nin gelişimini yakından görmesini sağladığı gibi Türkiye de ticari ilişkileri geliştirebilmek için bu ziyareti fırsat olarak görmüştür. Bu çalışmada Rıza Pehlevi’nin Türkiye’yi ziyaret ettiği 10 Haziran 1934-6 Temmuz 1934 tarihleri arasında Akşam gazetesinde yer alan yansımaları incelenmiştir. Akşam gazetesinin ilgili sayılarında Pehlevi’nin ziyaretiyle ilgili yer alan 108 haber içerik analizi yöntemiyle incelenmiştir. Çalışma sonucunda, Pehlevi’nin ziyaretine Akşam gazetesi hükümetin verdiği önemi gösterir derecesine ilgi gösterdiği ve bu ziyaretin iki ülke arasındaki dostluğu pekiştirmesi açısından önem arz ettiğini göstermektedir. Ayrıca bu ziyaretin sıradan bir ziyaretten öte stratejik bir öneme sahip olduğu ve ticari faaliyetlerin geliştirilmesi açısından ziyaretin amacına ulaştığı belirlenmiştir.
Orientalism and Christian Pilgrimage in Contemporary History
Authors: Haroun Heba Farouk , Al Naimat Salameh Saleh
Published: November 2024

This study focuses on the concept of orientalism and its relation to Christian pilgrimage in modern times, and the views of Western Christian religious figures, historians, researchers, and pilgrims to share their experiences with Christians who want to make a journey to the Holy Land, monks’ caves or other holy places around the world. The benefits of Christian pilgrimage in their view will be spiritual more than physical by visiting the Christian pilgrim's true places of pilgrimage. The invitation here is to teach Christians the religious ceremonies that were done by the early pilgrims who had followed Christ's steps and his apostles who took the Bible as their guide. According to them, pilgrimage is not for fun or entertainment but for worship and forgiveness, an idea that lasted for a long time until now. This study included an introduction, a definition of orientalism, and an explanation of the western Orientalists’ point of view of pilgrimage, by giving examples of pilgrims' stories who made their journey whether in reality or in a dream.
Lithic Procurement and Provisioning at the Lower Palaeolithic Site of Shishan Marsh 1 in the Azraq Basin, Jordan
Authors: Beller Jeremy A. , Murray John K. , Alsouliman Amer S.
Published: November 2024

Considerations of the landscape, the distribution and quality of resources, distances to outcrops, and proximity to other resources factor into the procurement decision-making by prehistoric foragers. However, the patterns of resource exploitation and utilisation are likely to vary by region, and those exhibited in marginal environments are not fully explored. This report focuses on the nature of lithic procurement and provisioning at the Lower Palaeolithic site of Shishan Marsh 1 in the Azraq Basin, Jordan. It draws upon several lines of evidence, including provenance and use-wear analyses performed on the biface assemblage. The results indicate raw material exploitation occurred at local and non-local distances to the site and the lithics were used for a variety of activities on medium-hard materials. Foragers moved toward the wetlands from significant distances on the surrounding landscape, likely bringing finished tools and, after use, discarding them in relatively good condition. The accumulation over time of ready-to-use tools at Shishan Marsh 1 points to a provisioning of the wetland margins for future needs.
The Memoirs (Ruznāma) of Ghiyāth al-Dīn Naqqāsh on His Journey to China During the Timurid Era (822-825 AH / 1419-1422 AD) and Its Historical and Cultural Value
Authors: Aykut Abdulsait
Published: November 2024

This article focuses on the identity of Ghiyāth al-Dīn Naqqāsh and discusses different versions of his text (Ruznāma), its translations into Turkish and Western languages, and previous research. The article also discusses the contents of the Ruznāma, Timurid-Chinese relations and Ghiyāth al-Dīn Naqqāsh’s observations about Chinese customs, city planning, and the ceremonies of hospitality in China; and compares those details in other documents and sources studied by historians of Chinese civilization.
Prediksi Jumlah Kunjungan Pasien Mental disorder Pelayanan Mentari Puskesmas Kecamatan Kalideres menggunakan ARCH, GARCH dan Box-Jenkins
Authors: Arifin Alicia , Wiyanti Wiwik
Published: November 2024

Pelayanan Mentari adalah pelayanan pasien mental disorder di Puskesmas kecamatan Kalideres, yang mana memiliki sub pelayanan Polania (poli anti aniaya) untuk menangani permasalahan bullying pada. Penelitian ini dilakukan untuk memprediksi jumlah kunjungan pasien di pelayanan Mentari. Data yang ditemukan menunjukkan bahwa 26,7% remaja di Indonesia mengalami gangguan cemas dan total prevalensi masalah kesehatan mental mencapai 46,8%, penting untuk mengidentifikasi pola data agar pemerintah bisa mengatasi masalah mental disorder sejak dini. Jenis penelitian yang digunakan adalah metode kuantitatif.  Tujuan dari penelitian ini adalah menggambarkan kondisi kesehatan mental di daerah Kalideres dan bisa memproyeksikan jumlah pasien mental disorder di daerah Kalideres, sehingga pemerintah bisa membuat kebijakan untuk menurunkan masalah mental disorder.  Data yang digunakan adalah data bulanan kunjungan pasien mental disorder pelayanan Mentari tahun 2020-2023. Metode analisa time-series yang digunakan adalah Box-Jenkins, ARCH dan GARCH. Metode yang terbaik adalah metode Box-Jenkins dengan ARIMA(1,1,1) yang mempunyai nilai MAPE sebesar 9,7%. Prediksi di bulan januari 2024 adalah 270,60 (95% CI,  204,97-336,23) dan bulan Februari 2024 sebanyak 269.31 (95% CI, 200,77 - 337,86). Hasil prediksi oleh model ARCH(1) sebesar 200,97(95% CI, -206,28-608,22), model GARCH(1,1) sebesar 191,95 (95% CI, -215,30-599,20).
Kata kunci: mental disorder, forecast, arima, arch, garch
A Study of Social Dynamics in Early Childhood Education Using the PEARS Model as a Mathematical Approach to the Spread of Cooperative and Independent Behaviors
Authors: Pratama Muhammad Isbar , Lismayani Angri
Published: November 2024

This study introduces the PEARS (Potential Adopters, Exposed, Active Adopters, Reluctant Adopters, Stable Adopters) model as a mathematical framework to analyze the spread of cooperative and independent behaviors in early childhood education (ECE) settings. Traditional qualitative methods have limitations in capturing the complexity of social dynamics within classrooms, so the PEARS model, adapted from epidemiological models, offers a fresh quantitative approach. The model categorizes children into five behavioral stages, tracking the transition from initial exposure to stable adoption. Through differential equations, the PEARS model quantifies behavioral spread and interactions, allowing the calculation of key metrics, including the basic reproduction number , which indicates the likelihood of behavior propagation within the group. Numerical simulations underscore the model's applicability in predicting behavior spread and evaluating intervention strategies, facilitating data-driven insights into enhancing positive social dynamics among young children. These findings have implications for designing pedagogical interventions aimed at fostering cooperative and independent behaviors in ECE environments.
Yeşil Alan Çevresindeki Farklı Kentsel Dokuların Mikro İklim Etkisinin Değerlendirilmesi
Authors: Yazıcı Esra , Yavaş Merve
Published: November 2024

Kent mikro ikliminin olumsuz etkilerini azaltmak için geçmişten bugüne yeşil alanlar potansiyel olarak önemli bir yere sahiptir. Kent ikliminin düzenlenmesinde önemli rol oynarlar ve farklı özelliklere sahip olsalar bile kent sıcaklıklar üzerinde olumlu etkiler oluştururlar. Bu doğrultuda çalışmanın amacı, soğuk iklime sahip olan Erzurum’da bulunan ve çevresinde farklı kentsel doku/yoğunluğa sahip bir kentsel yeşil alanın iklim simülasyonları yoluyla test edilmesi ve çevresindeki farklı kentsel dokuların mikro iklime etkisinin saptanmasıdır. Çalışma süresince seçilen kentsel yeşil alan için bitki örtüsü, çevresindeki yerleşim alanının yoğunluk analizi ve sıcaklık ölçümleri yapılmıştır. Yapılan analizlerin haritalarının üretilmesi aşamasında ENVI-met programı kullanılmıştır. Yapılan simülasyon sonucunda kentsel yeşil alanın yapılaşmış yakın çevresine göre yaz ayında ortalama 2.01 oC daha serin iken kış ayında ortalama 1.2 oC daha sıcak olduğu tespit edilmiştir. Kentsel yeşil alandan uzaklaştıkça yaz mevsiminde sıcaklığın arttığı, kış aylarında ise azaldığı görülmüştür. Ancak sonuçlar bu farkın kentsel dokuya göre değiştiğini, kentsel yeşil alanın mikro iklim etkisinin sadece alan içi özelliklere bağlı olmadığını ve yakın yapılı çevrenin özelliklerinin de etkili olduğunu göstermiştir.
Çin’de Felsefi Ortamı Doğuran Kent Devletleri ve Kent Devletlerini Şekillendiren Filozoflar
Authors: Ovalı Turgay
Published: November 2024

Çalışmanın amacı, antik Çin’de kent devletlerinin ve felsefi düşünce sistemlerinin aynı zamanda ortaya çıkmasından hareketle kent devletlerinin felsefi ortamı doğurduğunu, aynı şekilde kent devletlerinin filozof yöneticilerin eliyle şekillendirildiğini ortaya koymaktır. Bu amaçla Antik Çin’de felsefenin ortaya çıkmasında Çin’in kendisine özgü kent devletlerinin oynadığı rol ile antik Çin’in ilk filozoflarının, kent devletlerinde aldıkları başbakan, danışmanlık ve devlet adamlığı gibi görevlerle kent devletlerini nasıl şekillendirdiği üzerinde durulmuştur. Kent devletlerinin daha sonraki Çin tarihine iz bırakmadan ortadan kaybolmasında bu filozofların görüşlerinin etkileri de bulunmaktadır. Yöntem olarak kent tarihi disiplinini oluşturan Çinli ve Anglosakson yazarların ürettiği eserler incelenmiştir. Bunun yanında makalenin iddiasına uygun olarak arkeolojiden ziyade düşünürlerin kaleme aldığı antik metinlere başvurulmuştur. Çalışmada Çin’de kent devletlerini doğuran süreçler incelenmiş ve bu kent devletlerinin arasındaki mücadeleden doğan düşünce okullarına değinilmiştir. Düşünce ortamının hareketlenmesiyle kent devletlerine yön veren filozofların bazılarının fikirlerine kısaca değinildikten sonra kent devletlerinin bu fikirler doğrultusunda nasıl dönüşüm geçirdiği ele alınmıştır. Sonuç olarak Çin’de yaşanan siyasi ve toplumsal değişimlerle birlikte gelen çalkantılar Çin'de felsefi düşüncenin kapılarını açmış; devlet görevi alan filozoflar, Çin'de kent devletlerinin dönüşümünde birinci elden etkili olmuşlardır.
Kent ve Çocuk Çalışmalarında Kullanılan Katılımcı Sosyal Araştırma Yöntemlerine Dair Bir Değerlendirme
Authors: Karagöl Bezek Tuba , Özdemir Sönmez Nihan
Published: November 2024

ÖZ
Üzerinde barındırdığı fiziksel yapıların ötesinde; kullanıcılarının ihtiyaçları, istekleri, kültürleri, alışkanlıkları ile yaşayan, sosyal bir canlı olan kente dair alınan tüm kararlarda, hazırlanan planlarda, uygulanan dönüşümlerde ya da etkilerin ölçülmesinde katılımın sağlanması büyük önem taşımaktadır. Karar vericiler ya da yetkililer tarafından, katılım gözetmeksizin hayata geçirilen müdahalelerin, nihai kullanıcılar ile uyum sağlayamadığı, sorunlara çözüm getirmekte yetersiz kaldığı, yapılan tespitlerin eksik olduğu görülmektedir. Özellikle, kırılgan ve dezavantajlı sosyal grupların başında yer alan ve yetişkinlere kıyasla içinde bulunduğu mekândan etkilenme eğilimi daha yüksek bir grup olan çocukların da sürece dahil edilmesi büyük önem taşımaktadır. Çocuk katılımı, çocukların kendilerini etkileyen karar alma süreçlerine, katılımın değişik aşamalarında, düzenli ve sürekli bir şekilde görüş bildirmesi ve katılması, olarak tanımlanabilir. Bu makale ile, kente dair sosyal araştırmalarda çocuk katılımında kullanılan yöntemler üzerine genel bir bilgilendirme yapılarak, araştırmacılar için özet bir yol haritası ortaya koymak amaçlanmıştır. Bu bağlamda, öncelikle kentsel araştırmalara çocukların katılımının önemi vurgulanmış, ardından bu çalışmalarda izlenen adımlar genellenmiş, çocuk katılımının aktif ya da pasif oluşuna göre bir sınıflama yapılmıştır. Bu sınıflandırma içinde kullanımı en yaygın olan katılımcı yöntemler; uygulanışları, sağladıkları avantajlar ve barındırdıkları dezavantajlar ile derlenmiş, bu yöntemlerin uygulanmasında dikkat edilmesi gerekli olan hususlara etik başlığı altında yer verilmiştir. Son olarak genel bir değerlendirme yapılarak tek bir yöntem yerine birden çok yöntemin bir arada kullanılmasının sağladığı avantajlar verilen örneklerle desteklenerek belirtilmiştir. Böylelikle çocuk katılımına yer verilecek kentsel araştırmalar için özetleyici bir yol haritası oluşturulması hedeflenmiştir.
Analysis of the Russian market of educational programs in the field of additional professional education for specialists of pharmaceutical companies
Authors: Orlov Aleksandr S. , Sinotova Svetlana V. , Kashirina Larisa S.
Published: November 2024

Aim – conduct an analysis of the Russian market of educational programs in the field of additional professional education for specialists of pharmaceutical companies.
Material and methods. The analysis of the market of educational programs was based on the data of the annual reporting of a number of institutions of higher education for the period from 2017 to 2021. Based on the data obtained, the share indicators of educational organizations in the Russian market of educational programs in the field of additional education of specialists from pharmaceutical enterprises were determined. The share indicator was used to determine the concentration of the educational programs market and the level of competition in the market using the concentration index and the Herfindahl – Hirschman index, respectively. In addition, in the course of the work, such analysis methods as generalization, methods of logical, classification analysis were used when combining ongoing programs of additional professional education into groups of systemic and comparative analysis when assessing both the overall profitability of the market by year and the profitability of individual universities.
Results. Based on the analysis, data were obtained on the profitability of the market for additional professional education services for pharmaceutical industry specialists; the presence of a high level of concentration of educational services in the market of additional professional education with a slight level of competition was established; the features of the implementation of additional professional training for specialists in the pharmaceutical industry are determined.
Conclusion. The importance of additional professional education for specialists in the pharmaceutical industry has been confirmed. The further direction of development of the sphere of additional professional education for workers of pharmaceutical enterprises has been determined. The increase in the Russian market of additional educational programs based on current data on the development of the industry was justified. Recommendations have been formulated to expand the currently implemented programs of additional professional education based on the growing needs of the pharmaceutical market.
Analysis of a survey of the adult population on oral hygiene products
Authors: Shalova Kristina Y. , Mushkina Volga V. , Filinskaya Larisa V.
Published: November 2024

Aim – to assess the use of oral hygiene products by consumers as a method of primary prevention of the development of dental diseases, as well as to study their motivation when choosing personal oral hygiene products.
Material and methods. The study was carried out using an individually developed and validated questionnaire. The questionnaire included 21 questions. Respondents were selected by random selection. Respondents filled out questionnaires manually on paper or online using Google forms. The questionnaire data was processed using the Microsoft Excel 2016 and Statistica Version 10 software siutes.
Results. Established a low level of hygiene education of respondents (34% of respondents to the questionnaire visit a dentist twice a year or more, the main criterion for choosing toothpaste for 36% of respondents is the possibility of using the whole family, 53.5% of respondents do not matter the content of fluoride in the toothpaste, 89.1 do not use other sources of fluoride, less than 50% of those surveyed use additional means of oral hygiene. The results of the questionnaire showed that about 40% of respondents acquire oral hygiene products in a pharmacy and need professional consultations of specialists on the composition of toothpaste and its effectiveness, the right choice of toothbrush, which determines the area of knowledge, that a pharmaceutical worker should own.
Conclusion. Have been identified the information needs on oral hygiene products.
The need for training in proper oral care and orientation to timely treatment of the dentist for preventive purposes and at the first symptoms, as well as information on primary prevention measures to preserve the dental health of the population.
It is important to raise public awareness of the role of fluoride in the prevention of the development of caries, as well as to use additional means of oral hygiene products and fluoride sources. One way to improve public hygiene awareness is for a pharmacist to provide competent advice to pharmacists and to increase the level of completeness in the use of oral hygiene products by the consumer.
The Development of Multicultural Islamic Education in the Modern Era: Relevance and Challenges
Authors: Khasanah Uswatun
Published: November 2024

Multicultural Islamic Education is an education that emphasizes multiculturalism as one of the visions of education with the main character that is inclusive, egalitarian, and humanist but remains firmly based on spiritual and divine values based on the Qur'an and Sunnah. The type of research used is the qualitative method with a phenomenological approach. This research collected data through in-depth interviews, observation, and documentation. Researchers conducted epoché, followed by data analysis with three stages, namely data collection, data reduction, data presentation, and conclusion drawing/verification. The study's results demonstrate the relevance of developing multicultural Islamic education in the modern era, which provides high respect and guarantees for each individual. Therefore, it is incorrect to assume that Islamic education lacks humanistic elements. Furthermore, the study's findings indicate that the development of multicultural Islamic education is not a simple task. This study found challenges and obstacles in formulating and adopting multiculturalism in the world of Islamic education, including: differences in the boundaries of multiculturalism as an ideology, exclusivism in homogeneous groups, vague tolerance boundaries that have the potential to cause egocentrism, the selection of appropriate multicultural models and types for Islamic education, and the feasibility and readiness of each component of the Islamic education system. The study's results suggest several ways to enhance multicultural Islamic education, including the need to keep refining the discourse of multicultural Islamic education. Second, that must continue to deepen and explore the concept of education, which upholds values, beliefs, heterogeneity, plurality, diversity, and all aspects of community life within the context of studying Islamic teachings based on the Qur'an and Sunnah. Third, further research is needed to establish the concept and form of multicultural Islamic education that can be implemented in practice.
Ride-Hailing Drivers' Preferences for Fairwork Principles of Satisfactory Working Conditions and Fair Pay-Profit Distribution and Willingness to Form and Join Worker-Platform Co-Operatives in Kenya
Authors: Matabi Jared Mark Ochieno , Gicheru Esther Njoki , Kiganane Lucy Maina
Published: November 2024

Ride-hailing drivers (e-drivers) are among the platform workers who successfully embrace the worker-platform co-operative model's emergence to counter capitalistic ride-hailing platforms and their complex ecosystems, which align with fairwork principles of pay, condition, contracts and (platform) management. This study was conducted to determine the extent of ride-hailing drivers' preferences for satisfactory working conditions, fair pay-profit distribution and willingness to form and join worker-platform co-operatives in Kenya. The study was grounded in the social exchange theory, affective theory of social exchange, and utility theory. The researcher applied critical-realism research philosophy and multimethod research designs of discrete choice experiments and sequential explanatory mixed method research designs. Using the Yamane sampling formula, the study used quantitative data from 497 respondents from sampled 600 of the 20,000 e-drivers in the Nairobi Metropolitan Region. The quantitative data was analysed using multinominal logistic regression. Moreover, the study used qualitative data from 11 participants, which was analysed using thematic analysis. Results indicated that the two fairwork principles were statistically significant to e-drivers’ willingness to form and join worker-platform co-operatives. fair pay-profits distribution (FPD) principle, in particular, was a highly preferred fairwork principle in terms of e-drivers’ willingness to form and join the worker-platform co-operative model (Coeff=1.564, SE = 0.234, Z = 6.67, p< .001), compared to the satisfactory working conditions (SWC) principle (Coeff=0.783, SE = 0.156, Z = 5.012, p< .001). This study brings practical and theoretical contributions to improve the e-drivers’ benefits from the ride-hailing sector. Policymakers, promoters, and platform workers like e-drivers could understand how best to promote worker-platform co-operatives to succeed in the country’s societal context.
Quelli delle Langhe
Authors: Caffarelli Enzo
Published: November 2024

Un lettore ci scrive che, per identificare l’abitante della Langa (o delle Langhe), “nella lingua parlata della zona predomina il termine langhetto, dal piemontese langhet anziché langarolo, termine attestato in alcuni dizionari di lingua.
Proximate Analysis and Amino Acid Profile of a Traditional Alcoholic Beverage (Burukutu) Produced within Jos Metropolis, Plateau State, Nigeria
Authors: YUSUF Hajara Oyiza , MALLAM-DAUDA Mercy , AGAKWU Monica Ukungakpe , SALAWU Simpa John , MOSES Victoria Ojotule
Published: November 2024

This study set out to assess the nutritional (amino acids and proximate) composition of burukutu, a locally prepared alcoholic drink from 4 selected areas of Jos metropolis in Plateau State, Nigeria. Burukutu samples were collected from Kugiya, Tundunwada, and Hwolshe and Angwan Rukuba in Jos, Plateau State. Samples were subjected to proximate analysis to investigate the following: ash, moisture, content, crude fat, crude fibre, crude protein and total carbohydrate. Amino acids profile of each sample was also examined. The chemical composition of the burukutu samples exhibited varying levels of: Ash (0.05-0.60%), Crude fibre (1.10-2.50%), Crude fat (0.50-0.70%), Crude protein (1.34-1.99%), Moisture (4.50-5.00%), and Total carbohydrate (89.36-92.50%). Leucine (5.86-7.21 g/100g protein), alanine (4.55-5.61 g/100g protein), proline (4.26-5.89 g/100g protein) and aspartic acid (6.02-7.79 g/100g protein) alongside glutamic acid (2.01-18.24 g/100g protein) were the amino acids that appear in some substantial concentration of all the amino acids that were present in all the 4 burukutu samples. In conclusion, all the burukutu samples are low in fibre, fat and protein, but they are rich source of carbohydrate. Also, from this study it could be said that the burukutu is a rich source of the following amino acids: glutamic acid, leucine, alanine, proline, and aspartic acid..
GRAMSCI E OS CONSELHOS DE FÁBRICA (1919-1920)
Authors: Machado Marília Gabriella
Published: November 2024

No âmbito acadêmico e político, o nome de Gramsci irrompe em diversos cenários. No Brasil, o autor pôde ser analisado por diversos prismas: voltado à educação, às questões culturais, à política e até mesmo tornou-se alvo de muitas polêmicas infundadas. O Gramsci que intelectuais competentes examinam, mormente é estudado a partir do período em que o comunista sardo esteve no cárcere. Em contraponto, este artigo surge como fruto de pesquisa da obra pré-carcerária de Gramsci e tem como objetivo principal compreender as formulações teóricas e práticas do jovem sardo durante o Biennio Rosso, a partir de artigos publicados por Gramsci no L’Ordine Nuovo.
Recebido em 15 de julho de 2019Aprovado em 13 de agosto de 2019Editado em 10 de setembro de 2019
Relação entre uso de antibióticos na infância e doenças inflamatórias intestinais
Authors: Heloisa Helena Machado Alves Lima  , Danilo de Oliveira Teixeira  , Roberta de Lima Medeiros  , Matheus Sampaio Farina  , João Henrique Martins Fernandez  , Bhiannca Oliveira Máximo  , Giovanna Ferreira Tavares Silva  , Giovana Cristine Medeiros Tavares  , Rafaela da Silva Claudino de Oliveira  , Ygor Suzuki do Carmo  , Karine de Oliveira Costa  , Edselma Rodrigues Alves Braga  , Adriana Fernandes Torres  , Felipe Morais Moreira
Published: November 2024

Este estudo tem como objetivo investigar a relação entre o uso de antibióticos na infância e o desenvolvimento de doenças inflamatórias intestinais (DII), como a doença de Crohn e a colite ulcerativa. Foi realizada uma revisão integrativa utilizando as bases de dados Scientific Electronic Library Online (SCIELO) e Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS). Foram selecionados artigos publicados nos últimos cinco anos, utilizando os descritores “antibióticos”, “doenças inflamatórias intestinais” e “infância”, combinados com os operadores booleanos AND e OR. A metodologia seguiu rigorosos critérios de inclusão e exclusão, resultando em uma amostra final de estudos relevantes para a temática. Os resultados indicam uma associação significativa entre o uso precoce de antibióticos e o aumento da prevalência de DII, sugerindo a necessidade de políticas mais restritivas para a prescrição desses medicamentos em crianças. Conclui-se que o uso racional de antibióticos pode ser um fator importante na prevenção das DII na infância.
Os desafios no diagnóstico da Síndrome de Haff: Uma revisão integrativa
Authors: Martyres Gueiros Bruna , Costa Vaz Isabela , De Carvalho Alves Matheus , Do Espírito Santo Lima ALef Henrique , Do Espírito Santo Pingarilho Karolina , Oliveira e Silva Leandro Rafael , Moraes de Moraes Thayse
Published: November 2024

Introdução: A doença de Haff, também conhecida como “doença da urina preta”, é uma síndrome sem causa definida, tendo por característica uma condição clínica que desencadeia o quadro de rabdomiólise com início súbito de rigidez, dores musculares, entre outros sintomas. Correlaciona-se com o consumo de peixe, e acredita-se que envolva uma toxina termoestável presente nos pescados que desencadeia os principais sintomas. Por ser rara, há a necessidade de aprofundamento nessa temática, na busca por auxiliar no seu diagnóstico. Objetivo: Mapear as evidências científicas disponíveis relacionadas ao diagnóstico da Síndrome de Haff no âmbito mundial. Metodologia: Para isso, foram utilizadas as plataformas de dados Embase, SciELO, PubMed/MEDLINE, Scopus e LILACS. Resultados: As buscas nas bases de dados levaram à inclusão de 419 artigos, inicialmente. A utilização dos critérios de inclusão e exclusão resultaram na seleção de 21 artigos para a revisão. A partir da leitura foi possível identificar a existência de desafios para a realização do diagnóstico da síndrome na conjectura atual. A rara incidência acarreta na baixa quantidade de estudos, levando, em alguns casos, ao diagnóstico tardio ou incorreto. As principais abordagens incluem análises clínicas e exames laboratoriais. Foram identificados os sintomas mais recorrentes entre os estudos analisados. Conclusão: A carência de artigos resulta na dificuldade em estabelecer um diagnóstico rápido e preciso da síndrome, e a identificação dos principais sintomas pode auxiliar no reconhecimento rápido da doença e melhora no prognóstico dos pacientes.
ERAS (Enhanced Recovery After Surgery) Protocol in Oral and Maxillofacial Surgery: Narrative Review
Authors: Anderson Jara Ferreira  , Camila Coêlho Guimarães  , Isabella Bezerra Araújo Cirilo  , Maria Eduarda Batista Henriques  , Karolayne Dutra Félix  , Dárcio Brito da Cunha  , Etiene Pereira Duarte Lins  , HUDSON GOMES DE SANTANA ILAN , Arthur Felipe de Brito Andrade  , Maria Claúdia Oliveira da Silva  , Erick Andres Alpaca  , Mayara Rebeca Martins Viana
Published: November 2024

Introduction: Oral and maxillofacial surgery is a specialty that involves the diagnosis and treatment of pathologies related to the oral cavity, mandible, jaws and facial structures. In recent years, the ERAS (Enhanced Recovery After Surgery) Protocol has been implemented in various surgical areas with the aim of optimizing postoperative recovery. Objective: To understand the impact of this approach on the patient experience and clinical outcomes.  Methodology: This narrative review was conducted through a systematic search of the PubMed, Scopus and Google Scholar databases. The aim was to identify studies investigating the implementation of the ERAS Protocol in oral and maxillofacial surgery. Results: The studies reviewed showed that the implementation of the ERAS Protocol in oral and maxillofacial surgery resulted in a significant reduction in the length of hospital stay, with patients being discharged in 1 to 2 days. In addition, pain control was improved, with a reduction in the use of opioids by up to 50%. The reduction in post-operative complications, such as infections and respiratory problems, was another benefit observed, with a reduction of up to 40% in these complications. Discussion: The adoption of the ERAS Protocol has shown promising results in the recovery of patients undergoing oral and maxillofacial surgery. The benefits include better pain management, early mobilization and lower complication rates. Conclusion: The ERAS Protocol in oral and maxillofacial surgery has the potential to transform surgical practice, promoting faster and more effective recovery. More studies are needed to standardize its implementation and evaluate its long-term effects.
OSTEOSSÍNTESE DE FRATURA DE MANDÍBULA APÓS EXODONTIA DE TERCEIRO MOLAR INCLUSO
Authors: Jonas Wesley Jonas Barros vasconcelos , Porto Gabriela Granja , Medeiros Isaías Lopes de , Lima Victor Figueiredo Sabino de , Andrade Taysnara Ismaeley de
Published: November 2024

Casos de fratura mandibular resultante de exodontia são raros, desde que sejam usados os conceitos de cirurgia transoperatórios e as recomendações pós-cirúrgicas tenham sido rigorosamente atendidas. O tema tem a intenção de explorar as técnicas de fixação da mandíbula, em especial a técnica de Champy. O objetivo deste artigo é o relato de um caso de osteossíntese de fratura de mandíbula após exodontia de terceiro molar incluso. Como metodologia, este artigo utiliza o relato do caso de paciente do sexo feminino, 43 anos, que procurou o serviço de urgência e emergência em traumatologia bucomaxilofacial, com relato de exodontia de dente 48, há aproximadamente uma semana, sem melhoras de sintomatologia. É possível dizer que a técnica de Champy tem base na utilização de uma única placa na zona de tensão, que seria a região em que os cotos fraturados mostram a tendência a se afastar, criando dificuldade para diminuir. A técnica de Champy apresenta grande vantagem de possibilitar a realização por acesso intraoral na zona de linha oblíqua, com instalação rápida de uma placa, com redução e estabilização da fratura, concorrendo para a reparação óssea. É importante considerar que a técnica de Champy é eficiente e tem níveis consideráveis de êxito, desde que seu procedimento seja realizado de modo recomendado, conforme foi mostrado neste relato de caso.
Hydrocele in infants: surgical evaluation
Authors: Moreira França João Antônio , Rodrigues Guedes Sabrina , De Sousa Marques Crislaini , Coelho Chagas Ana Gabryella , De Oliveira Cardoso Lívia , Rodrigues Fernandes Duarte Rodrigo , Augusto Santana Silva Guilherme , Lacerda Ribeiro Patrick , De Souza Martins Gabriela , Arruda Prado Cavalcante Thiago , Bárbara Cardoso da Silva Thamires , Gonçalves Benevides Jessica , Campos de Figueiredo Gonçalves Ricardo , Lima Dourado Thais , Gomes Matos Rodolfo
Published: November 2024

Introduction: Hydrocele in infants is a condition characterized by fluid accumulation in the scrotum, often seen in newborns. This disorder, although often benign and self-limited, may require evaluation and, in some cases, surgical intervention. Understanding the factors associated with hydrocele, its clinical presentation, and therapeutic approach are essential to ensure appropriate management. The medical literature discusses the prevalence and implications of hydrocele, as well as guidelines for surgical evaluation in persistent cases, highlighting the importance of early identification and timely intervention. Methodology: The research followed the PRISMA checklist guidelines, using databases such as PubMed, Scielo, and Web of Science. Five descriptors were used: "hydrocele," "infants," "surgical evaluation," "treatment," and "clinical outcomes." Inclusion criteria included articles published in the last ten years, studies focused on infants, and that addressed the surgical evaluation of hydrocele. Conversely, exclusion criteria included non-systematic reviews, articles that did not specifically address the pediatric population, and studies with incomplete data. Results: The analysis revealed that most cases of hydrocele in infants resolve spontaneously, but surgery is recommended in cases of persistent or symptomatic hydrocele. The literature highlighted the importance of careful clinical evaluation and consideration of the risks and benefits of surgery. The main outcomes observed included surgical complication rates and parental satisfaction with the results. Conclusion: Hydrocele in infants requires a careful approach, taking into account both the often self-limiting nature of the condition and the potential associated complications. Surgical evaluation should be performed carefully, based on clinical guidelines and the experience of the medical team. The systematic review highlighted the importance of an individualized approach to each case, ensuring better outcomes for patients and their families.