bluuebunny/crossref_metadata_2025 huggingface dataset:
Proposing methods to explore the evolution of the term ‘mHealth’ on the Danish Web archive
Authors: Fage-Butler Antoinette , Ledderer Loni , Brügger Niels
Published: January 2022

This article uses Internet archives to explore the emergence and spread of the term ‘mHealth’ (mobile health technologies) in the Danish Web domain from 2006 to 2018, focusing on the actors that contributed to its evolution. We propose three methods for investigating the Web pages and Web sites that employed the term ‘mHealth’. Our findings highlight temporal developments in the use of ‘mHealth’, with diverse actors using it, though none clearly dominated. The article attends to challenges in working with Web archive data, and presents methods that can be used by others wishing to engage empirically with Internet archives, which remain vast, but largely under-exploited resources.
ON MODELS FOR CROSS-WORLD PREDICATION
Authors: Фролов Константин Геннадьевич
Published: January 2022

Я выдвигаю два методологических возражения против концепции кросс-мировой предикации, которую предлагает Е. Борисов: (1) Данный подход не учитывает того обстоятельства, что истинностный статус утверждений модального дискурса, как правило, интересует нас не в теоретико-модельном смысле, а в смысле истинности simpliciter. При этом данный подход не оставляет нам никакой возможности говорить о модальной эпистемологии и содержательном обосновании модальных утверждений. (2) Данный подход не учитывает роли воображения и ментального моделирования в том, что Е. Борисовым называется «интуитивным пониманием» рассматриваемых им утверждений. Учёт воображения и ментального моделирования, в свою очередь, переводит содержание подавляющего числа рассматриваемых Евгением примеров в разряд эпистемической модальности говорящего. При этом корректный переход от субъективной эпистемической модальности говорящего к любым типам объективных модальностей в рамках подхода Евгения попросту не может быть осуществлён, поскольку такой переход предполагает наличие внятной концепции модальной эпистемологии, чего Евгений нам не предлагает. Истинность любых рассматриваемых им примеров - это истинность на моделях говорящих, то есть на фреймах, в рамках которых говорящие полагают некоторые миры достижимыми из актуального.

I raise two objections to E. Borisov’s methodology for building the theory of cross-world predication: (1) This approach does not take into account the fact that usually we are interested in truth values of modal claims not in the model-theoretical sense, but in the sense of truth simpliciter. However, this approach does not leave us any opportunity to talk about modal truths simpliciter, modal epistemology and substantive truth conditions for modal claims. (2) This approach does not take into account the role of imagination and mental modeling in what E. Borisov calls the ‘intuitive meaning’ of the analysed claims. However, taking into account imagination and mental modeling shows that the vast majority of the cases under consideration deal with epistemic and not alethic modality. In the absence of any modal epistemology we cannot simply postulate the validity of modal truths. Such postulation would be puzzling and unexplainable. And without such postulation of factuality, all the modalities we consider turn out epistemic.
O cinema e educação no Endipe: um estado do conhecimento
Authors: Bulaty Andréia , Chincoviaki Luzia Rita , Nunes Ana Luiza Ruschel , Suarez Adriana Rodrigues , Lupepsa Letícia
Published: January 2022

O presente artigo objetiva mapear as produções sobre Cinema e Educação nos anais do ENDIPE de 2013 a 2020, tendo como interesse conhecer e compreender o que se tem produzido sobre Cinema e Educação no evento do Endipe nos últimos 7 anos. O período é influenciado pela aprovação da Lei n. 13.006/2014, que institui a obrigatoriedade do Cinema na escola. Utilizou- se como referencial teórico os autores Duarte (2002), Costa (2003) e Fresquet (2015). A pesquisa é do tipo “Estado do Conhecimento”, e buscou-se a partir de análise bibliográfica e documental, nos Anais e livro do Endipe, mapeando-se a produção científica com os seguintes descritores: Cinema e Educação; Educação e Cinema; Lei 13.006/2014 - Linguagem cinematográfica na escola; Leitura fílmica; cinema na sala de aula. Conclui-se com a pesquisa que nos 4 anais e e-book do evento do Endipe encontra-se um total aproximado de 4.191 trabalhos publicados, dos quais 45 artigos trazem a discussão sobre o Cinema e Educação.
A significação do negro em materiais didáticos: uma análise semântica de atividades relacionadas ao Dia Nacional da Consciência Negra
Authors: Silva Florisbete de Jesus , Campos Leonardo Lacerda
Published: January 2022

O objetivo deste artigo foi analisar como o negro é significado em atividades didáticas desenvolvidas para alunos/as do Ensino Fundamental, expostas na rede social Pinterest, para serem aplicadas em salas de aula no Dia Nacional da Consciência Negra. As discussões foram fundamentadas por teorias sociais que versam sobre a Lei No 10.639, de 9 de janeiro de 2003, e sobre as questões raciais. O aporte teórico de análise foi a Semântica Enunciativa do Acontecimento, teoria semântica desenvolvida pelo Professor Eduardo Guimarães, a qual considera o estudo da enunciação como o lugar onde o sentido é historicamente construído na relação do sujeito com a língua, no acontecimento, e o texto é visto como uma unidade complexa de significação que integra enunciados, os quais apresentam no seu funcionamento uma consistência interna e uma dependência relativa, que os fazem significar. Os resultados da análise demonstram que as atividades publicadas na rede Pinterest são marcadas por estereótipos que significam as pessoas negras com os mesmos sentidos de séculos passados, legitimando a discriminação e a invisibilidade, frutos do racismo ainda vigente na sociedade brasileira.
REGULATORY IMPACT ASSESSMENT IN THE AREA OF THE EURASIAN ECONOMIC UNION: PECULIARITIES OF FORMATION AND CURRENT STATUS
Authors:   Academy of Public Administration under the President of the Republic of Belarus, Minsk, Republic of Belarus, RUSAK Iryna , NOVIKOV Alexander ,   Academy of Public Administration under the President of the Republic of Belarus, Minsk, Republic of Belarus, NOVIKOV Sergey ,   Academy of Public Administration under the President of the Republic of Belarus
Published: January 2022

This article examines the process of formation of the regulatory impact assessment as a main tool of regulatory policy in the area of the Eurasian Economic Union. The influence of the taken regulatory measures on the activity of the entities is identified. The reasons for the necessity to develop regulatory impact assessment as a legal institution are described, its advantages are determined, the peculiarities of the development of this institution are studied. Legal framework that serves as a basis for assessment functioning is examined. The reasons for uneven development of the institution of assessment in the Eurasian area are understood, typical country peculiarities are given. On the basis of the conducted analysis suggestions for the improvement of the mechanism of the regulatory impact assessment are generated and its development perspectives are identified.
ANALYSIS OF THE SOCIAL EFFECTIVENESS OF THE IMPLEMENTATION OF YOUTH POLICY IN THE MUNICIPALITY
Authors:   Ural State Agrarian University, RUCHKIN Alexey , LATYPOV Rinat ,   Ural State University of Economics, YURCHENKO Nadezhda ,   Ural State Agrarian University
Published: January 2022

Migration of young people to big cities, active outflow of population to other regions of the country and for permanent residence in foreign countries forces to search more and more actively for new methods and technologies both to inform young people about their opportunities in the territory, and to change tools for retention for further development of cities and small settlements. In most cases the analysis of state and municipal policies for working with youth is determined by the economic sense, that is, the economic and financial efficiency of implemented programs is analyzed. The authors approached the problem under consideration from the sociological point of view in order to determine the needs directly from the subject, as well as to assess the managerial and organizational problems and obstacles to increasing the importance of activities for young citizens. The testing ground for the study was the Chaikovsky urban district in Perm Krai (population 103,000, medium-sized city).
Phytochemical analysis of commercially available Spirulina, their activities and Biosynthesis of Nanoparticles
Authors: M Monika , Prema K. Krishna
Published: January 2022

Spirulina is used as dietary supplement in form of capsules and tablets. It is rich in Bioactive molecules and exhibits various activities. Commercially available Spirulina was collected. Extracts were prepared using various polar and non-polar solvents. The extracts were used for qualitative phytochemical analysis and to determine their Anti-Oxidant, Anti-Inflammatory and Anti-Arthritic activity. Phytochemicals like Tannin, Carbohydrates and Glycosides were present in all the extracts, while others were present only in few extracts. Biosynthesis of Nanoparticles was done by using the extract. Chloroform extract and Nanoparticles showed higher Anti-Oxidant activity, Ethanol extract showed higher Anti-Inflammatory activity and Chloroform extract showed higher Anti-Arthritic activity.
Cervical Necrotizing Fasciitis: An Uncommon Fulminant Disease Entity
Authors: Sharma Manish Kumar , Sharma Archna
Published: January 2022

Cervical necrotizing fasciitis is an uncommon fulminant disease of single or polymicrobial infectious origin characterized by rapid necrosis of the subcutaneous tissue and fasciae. The disease has high mortality rate. Early identification, timely surgical debridement, broad spectrum antibiotic therapy, aggressive wound care and intensive medical care of the patient are of paramount importance for better prognosis. We present a case report and review of literature of cervical necrotizing fasciitis with a thorough insight into its epidemiology, etiology, pathogenesis, diagnosis and management.
Assessment of Role of Platelet Aggregation in Metastatic Breast Cancer Patients
Authors: Ramji Ashwini , C V Shanmugan
Published: January 2022

Background: To assess role of platelet aggregation in metastatic breast cancer patients.Methods:40 cases (Group I) of metastatic breast cancer patients and equal number of healthy control (Group II) subjects were included. Platelet aggregation studies in vitro using ADP and Thrombin were performed using an optical aggregometer. Detection of platelet aggregation was done by Chrono log series 490 dual and four channel optical aggregometer systems.Results:There were 4 subjects in group I and 12 in group II having ADP <60, 26 subjects in group I and 28 in group II with ADP 61-72 and 10 subjects in group I with ADP >72. Low thrombin <58 was seen in 8 in group II, normal thrombin between 61-72 was seen among 11 in group I and 32 in group II and high thrombin >82 among 29 in group I respectively. Amongst patients with normal platelet count, 14 patients had platelet aggregation with ADP in the normal range and 4 patients had platelet aggregation with ADP in the lower range. In patients with high platelet count, 12 showed aggregation in the normal range, and 10 patients showed aggregation in the higher range which was statistically significant (P< 0.05) (Table III, Graph II).Conclusion: Platelet aggregation has an important part to play in the tumor metastasis of breast cancer patients.
Anxiety and Depression in School-going children with Epilepsy
Authors: Francis Linus , Manuel Davis
Published: January 2022

Background: This study was designed to find the prevalence of anxiety and depression in school-going children with epilepsy.Methods:All the patients with epilepsy presenting during the study period underwent detailed clinical and EEG evaluation. Hospital Anxiety and Depression score (HADS) was used to screen for anxiety and depression.Results:We identified 190 patients with epilepsy during the study period. Out of these 30 (15.8%) were diagnosed as having treatment resistance epilepsy. Anxiety was diagnosed in 114 (60%) and depression in 62 (32.6%). Patients with drug resistant epilepsy were found to have statistically significant markers in the form of higher scores for depression and anxiety, and lower IQ scores. Frequency of GTCS (Generaized Tonic Clonic Seizures) showed inverse correlation with IQ scores and direct correlation to the anxiety/depression scores.Conclusion:We conclude that anxiety and depression in school-going children with epilepsy is common and that it has a correlation with treatment resistance.
Objective Assessment of Superiority of Enteral Feeding by Traditional Home Kitchen-Based Feed V/S Commercial Formula Feed in Patients of Esophagogastric Corrosive Injury
Authors: Bhadania Maulik S. , Vora Hasmukh B. , Jillawar Nikhil , Desai Premal R.
Published: January 2022

Background: Corrosive ingestion can cause severe chemical injury to upper gastrointestinal tract which leads to dysphagia, malnutrition and weight loss. Early nutritional assessment and support through feeding jejunostomy is important and it should be nutritionally optimum and economically balanced. The aim is to compare cost and nutritional status after nutritional support with traditional home kitchen made and commercial formula feed through feeding jejunostomy.Methods:A prospective study included patients on enteral nutrition based on traditional home kitchen feed (cohort-1) and on commercial formula feed (cohort-2). Patient’s body weight, BMI, haemoglobin, serum albumin, nutritional risk index, controlling nutritional status score were checked at the admission, 3rd and 6th month follow up.Results: In cohort 1 mean albumin and haemoglobin raised by 33.13% & 14.60% at 3rd month and 47.23% & 22.3% at 6th month respectively; In cohort 2 it was 9.12% & 2.69% at 3rd month and 17.62% & 6.53% at 6th month respectively. At 6th month in cohort 1 and 2 mean weight gain was 7.56% & 4.0%; mean increase in NRI was 34.78% & 11.5% respectively. Mean CONUT score at six months was better improved in cohort 1 which is 6 to 1 as compared to cohort 2 which was 6 to 3. Mean monthly cost of home-based feeds was significantly lower as compared to commercial feeds (62.14 Rs v/s 682-2354 Rs/day).Conclusions:In corrosive GI tract injury patient enteral nutrition with traditional home kitchen-based feeds is safe, cost effective and associated with better improvement in nutritional status objective parameters.
Prospective Evaluation of Raised Liver Transaminases in Asymptomatic Patients Attending OPD in a Tertiary Care Hospital
Authors: Ahuja Vivek , Singhal Raghav , Kumar Paraag
Published: January 2022

Background: Liver diseases are a cause of worldwide morbidity .The course is usually long and has no signs before the development of late stage disease. The only indicative markers are liver enzymes, such as aspartate aminotransferase (AST), alanine aminotransferase (ALT), and gamma glutamyl transferase (GGT) during asymptomatic period. There is a paucity of data from our subcontinent regarding the prevalence, risk factors and etiology of asymptomatic chronically raised liver enzymes.The aim of the study was to determine the prevalence, risk factors and etiology associated with unexplained chronically raised liver transaminases in patients attending OPD in a tertiary care hospital.Methods:This was a prospective study conducted in the Department of Gastroenterology, MMIMSR, Mullana from July 2019-Dec 2020 in 50 patients who presented with chronically raised liver enzymes. Detailed comprehensive history, physical examination and investigation was done to identify etiology and risk factors associated with raised liver enzymes.Results:566 patients were screenedfor inclusion in the study. The prevalence of raised transaminases in asymptomatic patients was 9.4%. NAFLD was the most common etiology of raised liver transaminases, seen in 70 % of patients followed by Hepatitis C and Hepatitis B. Dyslipidemia was the most important risk factor associated with NAFLD.Conclusion:NAFLD should be kept in mind while dealing patients with unexplained transaminitis. Earlier detection could help halt the progression to chronic liver disease.
Clinical profile of patients with esophageal carcinoma: A multicentric study from North India
Authors: Kumar Paraag
Published: January 2022

Background: Carcinoma esophagus is the 6th most common cancer in India with an incidence of 5.04% It most commonly affects older age individuals, with incidence peaking in seventh and eighth decades of life. Adenocarcinoma (AC) and Squamous cell carcinoma (SCC) are the two main histological variants. Our aim was to study the risk factors, clinical and epidemiological profile of patients diagnosed with Esophageal Cancer from two tertiary care centres located in North India.Methods:This was a retrospective study carried in departments of gastroenterology of two tertiary care hospitals North India. Data was collected from respective institutes for the previous 1 year i.e. from 1st October 2020 to 30th September 2021. All patients presenting to Gastroenterology OPD or emergency with dysphagia who were diagnosed as having Carcinoma esophagus were included in the study.Results:A total of 106 patients were included in this study. There were 44 females & 66 males. The most common presenting complaint was Dysphagia (48%) followed by Loss of weight (26.4%), Vomiting (in 23.6%) and Odynophagia (22.6%). Involvement of the lower one third of the oesophagus was the most common (37.7%). SCC (Squamous Cell Carcinoma) was the most common type of oesophageal carcinoma in this study, seen approximately in 80% of cases.Conclusion:Our study from North India suggested poor oral hygiene as a strong risk for carcinoma esophagus Males were more commonly affected and SCC was the predominant variant.
Our Management of Vestibular Schwannomas and Review of Literatures
Authors: Shunyu Neizekhotuo Brian
Published: January 2022

There is no a clear consensus provided in the literature and there remain controversial on the treatment especially for small to medium size Vestibular schwannomas (VSs). Thus the treatment technique and approach preference vary from centre to centre. This problem too exists in our centre. The purpose of this paper is to develop a consensus in our hospital among our colleagues on the treatment of our VSs patients. We have been treating VSs patient by translabyrinthine approach from time to time for the last 5 years and found it to be a very efficient approach. This approach gives the most direct route to the tumor with excellent exposure of the internal acoustic meatus, cerebropontine angle (CPA) area without the need to retract the brain with facial nerve totally in control early in the surgery. The only problem was, when there is large posterior fossa component of the tumor present. This approach is safe with direct exposure to CPA area and have minimum intraoperative or postoperative complications.
Transmuscular Quadratus Lumborum Block for Postoperative Analgesia in Laparoscopic Colorectal Surgery
Authors: Routray Sidharth Sraban
Published: January 2022

Background: Transmuscular Quadratus Lumborum Block (TQLB) is a newer modality for postoperative pain management. But, its efficacy after laparoscopic colorectal surgery is little researched. The aim of our trial was to access the analgesic efficacy of TQLB in colorectal surgery.Methods:This study was done in 64 patients posted for colorectal surgery who were divided into two groups of 32 each. TQLB was given bilaterally in group RQ with 20 ml of 0.375% ropivacaine and in group SQ with 20 ml saline. Patients were operated under general anesthesia and were examined for pain at different time points postoperatively. Time required for first analgesic demand was our primary endpoint. Secondary endpoints were total rescue analgesia (paracetamol) required in 24 hrs, pain scores, nausea, vomiting, sedation and any other complications.Results:The time required for first analgesic demand was 3.9± 0.8hrs in RQ group and 0.1± 0.2 hrs in group SQ which was statistically significant. The total paracetamol consumption in 24 hours was1.2± 0.4 gm in group RQ and 2.9± 0.7gm in group SQ ,the difference being remarkable.Conclusion:Transmuscular quadratus lumborum block can produce quality analgesia after laparoscopic colorectal surgery. TQLB not only improves the visual analogue scale (VAS) score but also decreases the rescue analgesic consumption without any complications.
Comparative Study of Outcome of Tympanoplasty by Postauricular and Permeatal Approach
Authors: Rahman Mushfiqur
Published: January 2022

Background: As from time of residency, tympanoplasty is the most common operation performed by an otolaryngologist. Because of the continuing efforts of otologists all around the world to produce the maximum surgical outcome, significant improvements in this surgical method have developed during the middle ages. Objective: The aim of the study was to compare the outcome of Tympanoplasty in Postauricular and Permeatal Approach.Methods:A total of 74 patients between the age group 15 to 44 years who were attending the ENT OPD, suffering from Chronic Suppurative Otitis Media (CSOM) were selected on the basis of type of perforation and their workup was done to assess the candidature for tympanoplasty. Comparative analysis between the two groups were done based on analysis using SPSS 24 software version. The level of significance was set to 5% (p < 0.05).Results:A total of 74 patients were included in the study and the overall graft take was 76.92% in cases of Permeatal technique as compared to 91.66% in the case of postaural underlay technique. The complication of postaural approach higher than Permeatal approach. There was a difference in hearing improvement with majority of the cases improving to the range of 10-22 dB in Permeatal technique compared to 08-18 dB in Postaural Underlay technique.Conclusion:In terms of complications and hearing improvement, the Permeatal method outperforms the Postauricular Approach, however the graft takes a higher percentage in the Postauricular Approach than the Permeatal Approach.
Cash holdings, tax policies, and institutional environments of innovative enterprises
Authors: Fengfei Chang Lee
Published: January 2022

We discover a positive association between a firm's innovativeness and its cash holdings using data from 11,653 innovative enterprises in 51 non-US economies. This relationship is even stronger now that patent boxes have been implemented, which provide preferential tax treatment for patent income. Additionally, creative multinationals that face increased repatriation taxes amass larger total cash holdings. The positive innovativeness–cash relationship is more pronounced in countries with higher R&D tax credits, less developed financial markets, stronger governance, stronger shareholder rights, more technicians, better infrastructure, and greater investment freedom, as well as in industries with fiercer competition and longer innovation cycles. Innovative organizations with greater cash on hand invest more in research and development and generate more patents. In general, our findings shed light on the factors that contribute to the massive wealth buildup in creative enterprises globally.
Panel evidence from rural Uganda on mobile money, risk sharing, and educational investment
Authors: Daniel Alves Abba
Published: January 2022

We investigate the influence of the rapidly developing mobile banking service "mobile money" on rural households' capacity to smooth their investment in education following a negative shock. We find that a negative shock reduces per school-age kid educational spending by 9.3 percentage points in families that do not utilize mobile money but by 8.3 percentage points in homes that have used mobile money. The underlying process is a rise in remittance receipts and sender variety as a result of the lower transaction costs afforded by mobile money. We demonstrate that our findings are resistant to alternative processes. We utilize the extension of the mobile money agent network as an exogenous variable in mobile money access.
A model for Ugandan traders' use of mobile money services
Authors: Mahdi Giozafat
Published: January 2022

Mobile money services give trade benefits such as bill payment, decreased transaction costs and time, expanded savings possibilities, sales, and convenience. Despite the benefits, traders in Uganda are still slow to adopt and use mobile money services. This article reflects on the findings of a study that looked at the barriers that merchants experience while utilizing and implementing mobile money services in Uganda. A self-administered questionnaire was utilized to obtain data from 394 survey respondents. A model for encouraging traders to use mobile money services is offered. The suggested model expands on the Unified Theory of Technology Acceptance and Use. According to regression study, performance expectancy, social factors, and sensitization components all have a substantial impact on the behavioral intention of mobile money service uptake for trade. On the other hand, security and effort expectation had no significant affect on traders' behavioral intention to use mobile money services. Furthermore, the data show that enabling conditions affected the utilization of mobile money services for commercial transactions. The suggested approach is adaptable and generic, and it may be used in other developing nations with comparable circumstances to Uganda.
Physical Activity and Exercise for Optimal Disease Prevention: Clinical Evidence
Authors: Sanders Gabriel
Published: January 2022

Previous physical activity guidelines from health organizations provide general physical activity and exercise intensity and duration recommendations. These guidelines have experienced very little change over the last two decades, despite significant changes in technology, more specifically wearable technology. The guidelines typical refer to exercise intensity as low, moderate and vigorous intensity based on a metabolic equivalent scale (MET) or a subjective scale. With wearable technology being accessible, affordable, reliable, and accurate, more attention should be given address recommendations that are multifaceted and specific. Most wearable technology can easily track sleep, steps, calories, hear rate, and exercise time within certain heart rate training zones. Research has shown that monitoring exercise and physical activity with wearable technology can improve health outcomes3.
Impact of Drug Abuse on Performance of Gymnasium Students in Germany
Authors:   Ludwig Maximilian University of Munich, Felicitas Pyrkosch Moritz , Ernst Leonard ,   Ludwig Maximilian University of Munic, Bendau Petzold Antonia ,   Ludwig Maximilian University of Munich
Published: January 2022

The education stakeholders in Germany acknowledge that alcohol and drug abuse among students are significant barriers to achieving academic goals. Alcohol and drug abuse are also related to an increase in other risky actions such as early sexual conduct, drunk driving, physical violence and truancy. Drug abuse in schools, particularly illicit drugs in high school, has long been a topic of concern. Thus, the study sought to examine the impact of drug abuse on the performance of college students in Germany. The study was literature-based and the inferences were based on the verdicts from the prior studies. The study results showed that drug abuse has a negative impact on performance. Drugs and alcohol are some of the most detrimental yet most common disruptions in teenage brain development. They manipulate the brain's wiring and affect how it processes and retains information, including how a teen thinks, focuses, learns, remembers, and concentrates inside and outside school. Drugs can impair teens' cognitive development and affect students' performance in school: reduce their ability to memorize things, poor concentration in the classroom and deficiency of prioritization of assignments. The study recommended that secondary school administrators develop a well-integrated learner surveillance system throughout school environments. Moreover, the government introduce life skills training in the syllabus to teach learners how to resist indulgence in drug abuse. Schools need to develop policies that promote participation in learning by creating environments that make it satisfying and interesting. In addition, the school administration should introduce and strengthen counselling and support services to students who demand social assistance. Keywords: Drug Abuse, Performance, Students, Germany
STUDIES ON NANOLIPID EMULGEL OF NIMESULIDE FOR TRANSDERMAL DELIVERY
Authors: Trimukhe C , Patil P. , Sheth K. , Desai N. ,   Department of Pharmaceutics, Bombay College of Pharmacy, Trimukhe C. Kalina, Santacruz (E), Mumbai - 400 098. Maharashtra, India
Published: January 2022

The objective of the present study was to develop and evaluate a nanolipid transdermal emulgel of Nimesulide. The nanolipid particles of Nimesulide were developed using Compritol 888 ATO and Labrafil M1944 as lipids, Polysorbate 80 as surfactant with Poloxamer 188 and Polyethylene Glycol 400 as stabilizer and cosolvent respectively. The nanoparticles were developed by Hot Nanoemulsification Low Temperature Solidification method and showed drug entrapment efficiency of 67 ± 2.316 % with particle size of 500 – 600 nm. TEM studies indicated presence of spherical particles in the nanometric range. The nanolipidic dispersions were suitably gelled to form emulgel. The in vitro release of the developed emulgel showed sustained drug release for 8 hours with no evidence of toxicity during histopathological testing after ex vivo permeation studies. The nanolipid emulgel of Nimesulide can thus provide sustained release action due to enhanced skin deposition for effective treatment of chronic arthritic conditions, thereby improving patient compliance.
DESIGN, SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL EVALUATION OF NOVEL BENZOTHIAZOLE BASED [1, 2, 4]-TRIAZOLO [4, 3-A] QUINOXALINE DERIVATIVES
Authors: Gadhave R. V. , Kuchekar B. S ,   Department of Pharmaceutical Chemistry, MAEER’s Maharashtra Institute of Pharmacy, MIT Campus, Kothrud, Pune - 411 038, Maharashtra, India
Published: January 2022

Quinoxaline, triazole and benzothiazole heterocycles plays an important role in modulating biological activity. The present work describes the biological evaluation of target molecules designed using autodock vina docker. Novel benzothiazole based [1, 2, 4]-triazolo [4, 3-a] quinoxalines were synthesized by condensation of substituted 2-amino benzothiazoles and 4-chloro triazoloquinoxalines. The synthesized compounds were characterized by analysis of physical and spectral data. All synthesized compounds were screened for antioxidant activity using 1, 1-Diphenyl-2-picrylhyrazyl radical scavenging, Hydrogen peroxide scavenging and Ferric reducing antioxidant power Method. The compounds 10g and 10i were found to be most active compounds of this series and other compounds showed moderate to less activity when compared with ascorbic acid. Study revealed that the most active compounds after structural modifications can be exploited as lead molecules for other pharmacological activities such as antimicrobial, anti-inflammatory, anticancer and antidepressant, activity.
PENGARUH KOMPENSASI, DISIPLIN KERJA, DAN MOTIVASI TERHADAP PRODUKTIVITAS KARYAWAN
Authors: Firmansyah
Published: January 2022

Abstrak

Tujuan dalam penelitian ini adalah untuk mengetahui pengaruh kompensasi, disiplin kerja, dan motivasi terhadap produktivitas karyawan di Kantor Jasa Penilai Publik (KJPP) Firmansyah & Rekan. Adapun isu – isu pokok yang akan di diungkap dalam penelitian ini adalah seberapa besar produktivitas kerja dari karyawan yang bekerja di KJPP Firmansyah & Rekan. Populasi dan sampel dalam penelitian ini adalah karyawan di Kantor Jasa Penilai Publik (KJPP) Firmansyah & Rekan. Pendekatan penelitian adalah pendekatan kuantitatif. Pengambilan sampel menggunakan teknik non-random sampling, yaitu dengan Teknik Purposive sampling. Sampel yang digunakan berjumlah 35 responden., dengan membagikan angket/ kuesioner dan teknik skala pengukuran menggunakan skala likert. Pengolahan data menggunakan SMARTPLS. Berdasarkan hasil uji hipotesis dari penelitian ini, yaitu adanya pengaruh antara kompensasi, disiplin kerja, dan motivasi terhadap produktivitas karyawan.

Abstract

The purpose of this study was to determine the effect of compensation, work discipline, and motivation on employee productivity in the Office of Public Appraisal Services (KJPP) Firmansyah & Partners. The main issues revealed in this research are how much work productivity of employees who work at KJPP Firmansyah & Partners. The population and sample in this study were employees at the Office of Public Appraisal Services (KJPP) Firmansyah & Partners. A research approach is a quantitative approach. Sampling used a non-random sampling technique, namely the purposive sampling technique. The sample used is 35 respondents, by distributing questionnaires/questionnaires and measuring scale techniques using a Likert scale. Data processing using SMARTPLS. Based on the results of hypothesis testing from this study, namely the influence of compensation, work discipline, and motivation on employee productivity.
The bahuvrīhi Compound Between Zeroing and Contrastive Accentuation: Vedic Sanskrit Model and Pāṇini’s Model
Authors: Rossi Paola Maria
Published: January 2022

This article aims to explore how Pāṇini’s model of the bahuvrīhi compound may be diachronically correlated to the bahuvrīhi compound as attested in the Vedic Sanskrit language, thus accounting for the two Pāṇinian requisites: zero-ending for all the constituents and accentuation on the first constituent, contrastively employed in relation to the determinative compounds. Since Pāṇini’s work is based on the Brahmanical scholarly tradition, the sources of his bahuvrīhi model are also to be found in the Brahmanical scholarly milieux. The locus classicus is the case of índraśatru, which starts off the process of uniformation and regulation of bahuvrīhi compound stressed on the first constituent. The same scholarly-discussed índraśatru compound is mentioned in the late Rigvedic textual layer (R̥V 1.32.6; 1.32.10), as an expressive poetic device. Therefore, the two Pāṇinian characteristic traits of the bahuvrīhi compound are inherited from a peculiar blend of poetic language and linguistic exegesis.
Caleb Williams, o l’umamanità divisa: letteratura e politica in William Godwin
Authors: Farinella Calogero
Published: January 2022

Storico dai molteplici interessi, bibliotecario, musicista, uomo di cultura e grande modernista, studioso, in particolare, dell’Italia settecentesca, Calogero Farinella ci ha prematuramente lasciati nel giugno del 2019, a poco più di sessanta anni. Le sue pubblicazioni sulla Genova del Settecento e sulla scienza illuminista (veronese specialmente: Francesco Bianchini, Anton Mario Lorgna e l’Accademia dei Quaranta) fanno e faranno sempre data negli studi di storia della cultura. Allievo tra i più brillanti di Salvatore Rotta (1926-2001), dal quale mutuò la passione per il XVIII secolo in particolare, Farinella si laureò sotto la sua guida su William Godwin (1756-1836), padre di Mary Shelley, filosofo e scrittore politico di area libertaria, che, con la sua fondamentale opera, marchia a fuoco il passaggio, in Gran Bretagna, dai Lumi al Romanticismo. Sulla figura e gli scritti di Godwin, ricavandoli dalla propria dissertazione di laurea, Farinella estrasse e pubblicò, negli anni Ottanta del secolo scorso, due articoli, apparsi nel volume della «Miscellanea storica ligure» contenente gli Studi in onore di Francesco Cataluccio (William Godwin ed il suo Journal all’epoca della Rivoluzione Francese, xv, 1984), e poi su Studi settecenteschi (Il governo più semplice. Il mito democratico-repubblicano in William Godwin, viii, 1987). Un terzo ampio articolo, che contiene spunti davvero interessanti sul romanzo utopistico di Godwin, rimase inedito, sino a oggi, malgrado l’oggettivo e rilevante valore del contributo di Farinella. Crediamo, pertanto, di fare cosa gradita alla memoria dell’amico e dello studioso pubblicandolo per la prima volta, in questa sede.
Attraverso Deleuze e Simondon: ontogenesi, processo e relazione
Authors: Zanelli Silvia
Published: January 2022

Obiettivo del presente contributo è tracciare una cartografia della nozione di individuazione, nella sua relazionalità con la dimensione del pre-individuale, lavorando tra il pensiero di Gilles Deleuze e Gilbert Simondon, attraverso un percorso di ripensamento dell’idea di umanità. Si vorrebbe cioè mostrare come sia possibile risemantizzare la vexata quaestio della “Fine dell’Uomo”, rileggendola piuttosto come un problema di con-fini e di margini, sempre attivi e divenienti. Al fine di mettere in luce questa costitutiva interrelazione fra il campo del pre-personale e dei processi di individuazione, si prenderanno in analisi i concetti di differenza, affettività e di “comunismo ontologico”.
Una bestia da guidare
Authors: Casella Federico
Published: January 2022

The aim of this paper is to analyse the numerous metaphors that Plato employs in his Republic to symbolise the ignorance, the immorality, and the political inadequacy of the “multitude”, in other words the people who live in a democracy. Plato’s symbols highlight the negativity – illustrated in other dialogues as well – of the Athenian demos in order to suggest the only political role that people must play: becoming subjects of the “divine” philosophers in the perfect city described in the Republic. Only by relying on philosophers’ guidance can the multitude be saved from itself: through one of the most recurrent symbols of the demos, the animal, Plato reveals his scepticism towards democracy and his preference for an oligarchy ruled by philosophers.
Segnico, simbolico, politico
Authors: De Toffoli Matteo
Published: January 2022

This article explores some central features of the theory of signification put forward by Ernesto Laclau and Chantal Mouffe, taking into account both Hegemony and Socialist Strategy and some further reflections developed by Laclau alone. Through the analysis of the concepts of discourse, empty signifier, dislocation and antagonism it is argued that, in the discourse-theoretical framework, the Saussurean “arbitrariness of the sign” can be limited only through the symbolic unification of a discourse and the drawing of antagonistic frontiers, and that these latter processes rest on contingent decisions, that is operations pertaining to the order of the political.
Miti e utopie della modernità nelle Riflessioni sulla violenza di Georges Sorel
Authors: Galletta Viviana
Published: January 2022

This paper analyses the work Riflessioni sulla violenza written by Georges Sorel and published in 1908. The principal aim of this paper is to present the deep relationship between myth, violence and politics in order to reevaluate how irrational forces have guided social movements and revolutions. The distinction between the notions of force and violence introduces the central thesis of Georges Sorel’s political thought, which is called anarcho-syndacalism. More specifically, George Sorel puts together Marx and Bergson in order to develop a severe criticism of the Third Republic and to theorize the role of violence in the transition from capitalism to socialism. Through the myth of the general strike, Sorel introduces his philosophical perspective on social struggles against the parlamentarism.
Dinamiche della bellezza: sguardo e narrazione nel ritratto
Authors: Borutti Silvana
Published: January 2022

Through the commentary on portraits (Lotto, Giorgione, Vermeer, L. Freud, Rembrandt, Tiziano, Bacon…), my contribution will develop two topics. In fact, the portrait calls to reflect both on the reversible dynamics of the gaze (between painter, subject and spectator, between presence and absence) and on the time of the individual as an experience and as a transformative process that tells a story.
Il Grande Oltre
Authors: Boccali Giuliano
Published: January 2022

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Per Marcello Conati
Authors: Scaramuzza Gabriele
Published: January 2022

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Recensione a Travail et pouvoir d’agir
Authors: Trimarchi Gianni
Published: January 2022

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Enrico Berti, in memoriam
Authors: Civello Gabriele
Published: January 2022

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Nikiel i jego związki. Metoda oznaczania w powietrzu na stanowiskach pracy
Authors: Wasilewski Paweł
Published: January 2022

Nickel due to its physicochemical properties is used to produce high strength, corrosion resistant, temperature resi-stant, high resistance and acid resistant alloys. Nickel in the form of fine powder can induce an allergic response when in contact with the skin, carcinogenic properties have been proven with long-term exposure to nickel dust. According to the proposed directive of the European Parliament No. 2020/0262, a value of maximum allowable concentration (MAC) in a workplace air in Poland for the inhalable fraction should be at 0.05 mg/m3 and for the respirable fraction at 0.01 mg/m3 (2020/0262/COD). The aim of this study was to develop a method for determining nickel in the range of 1/10 ÷ 2 of the MAC. The method is based on gathering nickel aerosol and its compounds contained in the air on a filter, filter mineralization in nitric acid(V) and hydrochloric acid at elevated temperature then determination of nickel content in the sample using atomic absorption spectrometry (AAS) with flame atomization. The method for the determination of nickel is presented in the form of an analytical procedure, which is included in the appendix. This article discusses the problems of occupational safety and health, which are covered by health sciences and environmental engineering.
Behaviour of recurving cyclonic storms in Arabian Sea as a response to atmospheric interactions
Authors: SHYAMALA B. , SUDEVAN S. , SHINDE G. M. , BURTE M. D.
Published: January 2022

During the year 1998, Arabian sea witnessed two distinct and unusual cyc\onic systems. The very severe cyclonic storm of June 1998 was the most severe storm since last fifteen years as far as Arabian Sea systems are concerned; while October 1998 system was unique for, Its unusual and sudden easterly track after almost touching Saudi Arabia coast, (ii) Very high speed of movement and (iii) Interaction and merger with another vortex present in Arabian Sea off Saurashtra coast.

 

This study is an attempt to understand the peculiar behaviour of the systems in Arabian sea which do not intensify beyond cyclone stage or even show a tendency to weaken before crossing coast as a response to atmospheric interactions. All the cyclonic systems in Arabian Sea since 1975 (Satellite era) have been examined in detail and the main findings of the study are :

 

(i) Interaction between cyclonic disturbances of different intensities simultaneously present, appears to be the key factor in determining the further intensification or not of the systems.

(ii) Track prediction for the systems upto marginal cyclone stage appears to be governed mainly by middle level atmospheric forcing.

(iii) Upper level wind steering is found to be important for movement of systems from severe cyclonic storm stage onwards.

 

The above results have direct relevance to operational cyclone forecasting.
Cloud climatology of the Indian Ocean based on ship observations
Authors: RAJEEVAN M. , PRASAD R. K. , DE U. S.
Published: January 2022

Surface cloud data based on synoptic observations made by Voluntary Observing Ships (VOS) during the period 1951-98 were used to prepare the seasonal and annual cloud climatology of the Indian Ocean. The analysis has been carried out by separating the long-term trends, decadal and inter-annual components from the monthly cloud anomaly time series at each 5° × 5° grids.

 

Maximum zone of total and low cloud cover shifts from equator to northern parts of India during the monsoon season. During the monsoon season (June-September), maximum total cloud cover exceeding 70% and low cloud cover exceeding 50% are observed over north Bay of Bengal. Maximum standard deviation of total and low cloud cover is observed near the equator and in the southern hemisphere. Both total and low cloud cover over Arabian Sea and the equatorial Indian Ocean are observed to decrease during the ENSO events. However, cloud cover over Bay of Bengal is not modulated by the ENSO events. On inter-decadal scale, low cloud cover shifted from a "low regime" to a "high regime" after 1980 which may be associated with the corresponding inter-decadal changes of sea surface temperatures over north Indian Ocean observed during the late 1970s.
A case study of the impact of INSAT derived humidity profiles on precipitation forecast by limited area model
Authors: RAO Y .V. RAMA , PRASAD K. , PRASAD SANT
Published: January 2022

The impact of humidity profiles estimated from INSAT digital IR cloud imagery data on initial moisture analysis in the IMD's operational limited area forecast system has been investigated. Method for assimilation of humidity profiles data as pseudo observations in the analysis scheme has been developed and implemented in the regional analysis scheme. Verification of humidity analysis with this data has shown substantial improvements in the moisture analysis over the data sparse region of tropics. Impact of the improved humidity analysis on model predicted rainfall is examined. The experiments show improved rainfall prediction.
IMPLEMENTASI TEKNIK COUNTER PADA AIR MANCUR UNTUK MEMBUAT ANIMASI AIR BERBASIS MIKROKONTROLER ATMEGA 16
Authors: Utama Candra Cahaya , Syahputra Trinanda , Iswan Mochammad
Published: January 2022

Air mancur merupakan salah satu penghias dipekarangan rumah. Kebanyakan air mancur pada umumnya yang memiliki variasi biasa-biasa saja, hanya mengeluarkan air yang menyembur ke atas saja sehingga mengurangi keindahan dan membuat kurang menarik perhatian. Sistem rancang bangun system otomatis pada animasi air mancur otomatis dapat diatur dan diprogram didalam Mikrokontroller. Mikrokontroller adalah sebuah Chip yang dapat melakukan pemrosesan data secara digital sesuai dengan perintah pemrograman. Dalam sistem ini akan mengembangkan sebuah air mancur yang dapat mengeluarkan animasi-animasi di setiap semburan airnya untuk menjadi tambahan daya tarik bagi masyarakat. Sistem kendali yang digunakan merupakan sistem kendali Timer Counter yang di implementasikan di air mancur.
More is more
Authors: Chiodi Vera , Escudero Verónica ,   International Labour Organization. Research Department.
Published: January 2022

What works to reduce child labor in agriculture? In this paper, we evaluate two randomized livelihood intervention programs, aimed to reduce child labor, particularly in its most exploitative forms, in rural areas of Peru and the Philippines. In the first randomized experiment, we evaluate a livelihood intervention provided to farmers in Peru that use the labor of their children on their family farms, accompanied by an education intervention aimed to improve the quality of schools and an awareness-raising intervention. In the second randomized experiment, we evaluate the incremental effect of the livelihood intervention implemented within a similar program in the Philippines, focused on the sugarcane agricultural sector. We find that when livelihood interventions were provided alone, they did not manage to improve economic conditions, and hence generally failed to reduce child labor rates in rural areas. However, when the livelihood intervention was combined with measures to improve the quality of education in Peru, we see a reduction in hazardous child labor and child labor overall. Awareness-raising interventions, aimed at changing the perceptions of parents through community interaction, appear to have also had an effect in the reduction of child labor, and these effects were reinforced by education interventions. Results indicate that a comprehensive approach including livelihood support with education and awareness-raising components is a more effective way to reduce child labor and hazardous labor for children in the agricultural sector.