bluuebunny/crossref_metadata_2025 huggingface dataset:
O comportamento infocomunicacional dos alunos universitários na apropriação de objetos digitais no quadro do direito autoral: o caso dos alunos dos cursos de Biblioteconomia e Ciência da Informação das universidades federais do Brasil e públicas de Portugal
Authors: Silva Jaciara Januario , Oliveira Lídia , Furtado Cássia
Published: February 2020

A reconfiguração do ciberespaço altera as dinâmicas sociais e coloca em evidência questões de cunho sociocultural, informacional, comunicacional e ético, a partir do acesso, uso e reuso de objetos digitais, de forma não consentida pelo autor das criações intelectuais. Contudo, essa abundância de conteúdos disponibilizados no ciberespaço requer dos utilizadores novas formas de agir, interagir e reagir diante deles. Assim sendo, esta investigação objetiva analisar os usos e representações dos estudantes dos cursos de Biblioteconomia e Ciência da Informação das universidades federais do Brasil e públicas de Portugal na utilização dos objetos digitais, nos âmbitos acadêmico e social, de forma articulada com as leis que regulam o direito de autor no ciberespaço. O desenho metodológico desta investigação segue o paradigma interpretativo e possui natureza mista (qualitativa e quantitativa). Os instrumentos de recolha de dados e fontes de informação são: a) inquéritos por questionários e entrevistas (aos diretores e coordenadores dos cursos e alunos); b) repositórios de trabalhos científicos, artigos científicos, entre outras fontes; e c) documentos (legislações e currículos dos cursos). O locus da investigação corresponde aos Cursos de Biblioteconomia e Ciência da Informação das universidades federais do Brasil e públicas de Portugal, tendo como participantes alunos dos primeiros e últimos anos e Coordenadores/Diretores dos cursos. Considera-se que a análise dos comportamentos infocomunicacionais dos participantes envolvidos na investigação terá impacto no desenho curricular dos cursos, de forma a garantir reflexões sobre o significado real do uso consciente desses objetos, a partir de um enquadramento legal.
Taxonomia inicial para o vocabulário e as enunciações extraídas de um corpo de editais de concursos públicos para profissionais da informação no Brasil
Authors: Paleta Francisco Carlos , Moreiro Gonzalez José Antonio
Published: February 2020

Este trabalho tem por objetivo apresentar resultado de projeto de pesquisa em andamento, conduzido no Observatório do Mercado de Trabalho em Informação e Documentação – CNPq, da Escola de Comunicações e Artes da Universidade de São Paulo em colaboração internacional com Universidade Carlos III de Madrid. Se categoriza e desenvolve hierarquicamente a terminologia que representa o conhecimento específico necessário para passar nos testes e os enunciados das atividades a realizar nos concursos para o setor público brasileiro de Ciência da Informação. Como processo metodológico, a fonte dos termos são os editais dos concursos publicados entre 2015 e 2019 para arquivistas, bibliotecários e museólogos, junto a outras fontes procedentes de trabalhos anteriores do grupo de pesquisa. Apenas as declarações e termos relacionados às atividades e conhecimentos digitais são extraídos. A lista hierárquica das atividades é composta escassamente por 64 entradas, o que determina uma grande limitação quando da aplicação à uma oportunidade de emprego no setor privado. Porem as 651 entradas de termos são uma boa representação dos conhecimentos específicos requeridos e servirão para processar o corpus de anúncios de emprego a selecionar. Seus termos serão automaticamente marcados a partir da lista aqui oferecida. Uma vez que a comparação entre a lista e o texto das ofertas de trabalho não fornecerá uma correspondência exata das sequencias, deverá ser utilizado um software que permita estabelecer equivalências entre os termos deste vocabulário e as expressões dos anúncios de oferta de trabalho.
Módulo híbrido de microfiltração e carvão ativado com nanopartículas metálicas
Authors: Ueda Yamaguchi Natália , Jenifer Rubio Andressa , Soto Herek Rezende Luciana Cristina , Bergamasco Rosângela
Published: February 2020

Esta pesquisa desenvolveu um material bactericida com a impregnação prata e cobre em carvão ativado granular (CAG/AgCu) para um módulo híbrido de microfiltração gravitacional. Para composição do módulo de filtração, foi utilizada uma membrana de acetato de celulose comercial e determinadas concentrações de 0,5% de prata e 0,5% de cobre em massa de CAG. Os materiais adsorventes foram caracterizados por técnicas de adsorção de nitrogênio, microscopia eletrônica de varredura (MEV), espectrometria de energia dispersiva (EDX), microscopia eletrônica de transmissão (MET) e difração de raios-X (DRX). A eficiência do módulo híbrido foi verificada por meio da avaliação do fluxo permeado, pH, turbidez, remoção de cloro livre e eficiência bactericida. O filtro apresentou remoções de cloro e Escherichia coli superiores a 90% e 3,7 log respectivamente, revelando seu potencial na tecnologia de filtros para tratamento de água.
ESTRUTURA E COMPOSIÇÃO FLORÍSTICA DE UM FRAGMENTO DE FLORESTA SEMIDECÍDUA NA REGIÃO AGRESTE DO ESTADO DA PARAÍBA, NORDESTE BRASILEIRO
Authors: Pinto Anderson Silva , Monteiro Fernanda Kalina da Silva , Lopes Sérgio de Faria
Published: February 2020

Na região Nordeste as florestas semidecíduas estão sendo substituídas por grandes lavouras e pequenas plantações. Nesse sentido, levantamentos fitossociológicos se fazem importantes por abordar aspectos ligados a estrutura, composição e o estado de conservação dos fragmentos remanescentes ameaçados. Assim objetivou-se descrever a estrutura e composição florística da comunidade arbórea de um fragmento de floresta estacional semidecidual no município de Lagoa Seca, Paraíba, Brasil. Para isso, foram alocadas 25 parcelas permanentes com dimensões de 400m², sendo todos os indivíduos com circunferência à altura do peito > 15 centímetros aferidos. A partir dos dados coletados foram elaboradas listas florísticas, fitossociológicas, gráficos de distribuição de classes de diâmetro e altura, índice de diversidade de Shannon (H’) e área basal total da comunidade. Foram amostrados 1835 indivíduos, pertencentes a 76 espécies e 27 famílias botânicas. O índice de Shannon (3,61) foi considerado alto enquanto o valor de área basal total (23,99 m²/ha) foi considerado baixo quando comparados a outros fragmentos semelhantes. Apesar da alta diversidade, o baixo valor de área basal pode estar relacionado a fatores antrópicos, uma vez que foi percebido que o corte seletivo é constante na área, podendo ser este o mesmo cenário vivenciado por outras áreas ainda não amostradas.
CULTURA E CRIAÇÃO, ARTE E NATUREZA
Authors: Tonezzi José , Coelho Paula
Published: February 2020

Comentários e apresentação da edição.
The odd flexible Weibull-H family of distributions: Properties and estimation with applications to complete and upper record data
Authors: El-Morshedy M. , Eliwa M.S.
Published: February 2020

In this paper, a new generator of continuous distributions called the odd
flexible Weibull-H family is proposed and studied. Some of its statistical
properties including quantile, skewness, kurtosis, hazard rate function,
moments, incomplete moments, mean deviations, coefficient of variation,
Bonferroni and Lorenz curves, moments of the residual (past) lifetimes and
entropies are studied. Two special models are introduced and discussed
in-detail. The maximum likelihood method is used to estimate the model
parameters based on complete and upper record data. Adetailed simulation
study is carried out to examine the bias and mean square error of maximum
likelihood estimators. Finally, three applications to real data sets show
the flexibility of the new family.
Sufficient oscillation conditions for deviating difference equations
Authors: Chatzarakis George
Published: February 2020

In this paper sufficient oscillation conditions are established, for deviating
difference equations with non-monotone arguments and nonnegative coefficients.
An example, numerically solved in MATLAB, is also given to demonstrate the
applicability and strength of the obtained conditions over known ones.
On transmission-type problems for the generalized Darcy-Forchheimer-Brinkman and stokes systems in complementary lipschitz domains in R3
Authors: Albişoru Andrei-Florin
Published: February 2020

The aim of our work is to give a well-posedness result for a boundary value
problem of transmission-type for the nonlinear, generalized
Darcy-Forchheimer-Brinkman and Stokes systems in complementary Lipschitz
domains in R3. First, we introduce the Sobolev spaces in which we seek our
solution, then we define the trace operators and conormal derivative
operators that are involved in the boundary conditions of our treated
problem. Next, we state a result that concerns the well-posedness of the
transmission problem for the generalized Brinkman and Stokes system in
complementary Lipschitz domains in R3. Afterwards, we state and prove an
important lemma. Finally, we obtain our desired result by employing the
well-posedness of the linearized version of our problem and Banach?s fixed
point theorem.
Scalarization and well-posedness for set optimization using coradiant sets
Authors: Yao Bin , Li Sheng
Published: February 2020

The aim of this paper is to study scalarization and well-posedness for a
set-valued optimization problem with order relations induced by a coradiant
set. We introduce the notions of the set criterion solution for this problem
and obtain some characterizations for these solutions by means of nonlinear
scalarization. The scalarization function is a generalization of the
scalarization function introduced by Khoshkhabar-amiranloo and Khorram.
Moveover, we define the pointwise notions of LP well-posedness,
strong DH-well-posedness and strongly B-well-posedness for the set
optimization problem and characterize these properties through some scalar
optimization problem based on the generalized nonlinear scalarization
function respectively.
Well-posedness results for a sixth-order logarithmic Boussinesq equation
Authors: Pişkin Erhan , Irkıl Nazlı
Published: February 2020

The main goal of this paper is to study for a sixth-order logarithmic
Boussinesq equation. We obtain several results: Firstly, by using
Feado-Galerkin method and a logaritmic Sobolev inequality, we proved global
existence of solutions. Later, we proved blow up property in infinity time
of solutions. Finally, we showed the decay estimates result of the
solutions.
On coincidence point and fixed point theorems for a general class of multivalued mappings in incomplete metric spaces with an application
Authors: Baghani Hamid , Agarwal Ravi , Karapınar Erdal
Published: February 2020

In this paper, weprove existence of fixed and coincidence points for a
general class of multivalued mappings satisfying a new generalized
contractive condition in incomplete metric spaces which generalize a number
of published results in the last decades. In addition, this article not only
brings a new approaches on the subject and but also involves several
non-trivial examples which demonstrate the significance of the motivation.
Finally, the obtained results of this paper provide a result on the
convergence of successive approximations for certain operators (not
necessarily linear) on a norm space (not necessarily a Banach space). In
particular, we conclude that the renowned Kelisky-Rivlin theorem works on
iterates of the Bernstein operators on an incomplete subspace of C[0,1].
Incremental, Critical Plane Analysis of Standing Wave Development, Self-Heating, and Fatigue during Regulatory High-Speed Tire Testing Protocols
Authors: Mars William V. , Paudel Govind , Suter Jesse D. , Robertson Christopher G.
Published: February 2020

Tire speed ratings derive from regulatory testing in which tire structural integrity is validated over a series of steps with successively increasing speed. For the FMVSS 139 high-speed standard, there are four half-hour duration speed steps at 80, 140, 150, and 160 kph. Speed ratings from Q through Y may be attained through the UN ECE R30 regulation high-speed testing. For either protocol, a tire must demonstrate the ability to operate without crack development at high speed for a specified period. After the test, “there shall be no evidence of tread, sidewall, ply, cord, inner liner, belt or bead separation, chunking, broken cords, cracking, or open splices.” A workflow for simulating regulatory high-speed durability performance has been developed based upon (1) recent improvements to the Abaqus steady-state transport formulation that now permit converged solutions to be obtained at high speed (including after the development of standing waves in the tire) and (2) Endurica DT self-heating and incremental fatigue simulations that account for thermal effects and for damage accumulation occurring due to a schedule of load cases. The self-heating calculation features the Kraus model and accurately captures viscoelastic loss modulus dependence on strain amplitude and temperature. For each step of the high-speed procedure, steady-state structural and thermal solutions are first computed. The deformation history in the presence of standing waves is shown to require rainflow counting due to the occurrence of multiple load cycles per tire revolution. Crack growth is finally integrated for each potential critical plane through each step of the test until failure is indicated. Standing waves at high speed induce significant self-heating and damage, rapidly limiting high-speed performance. The temperature dependence of self-heating and strength properties also plays a major role in limiting high-speed durability. The simulations were executed on both a flat surface and on the regulation specified 1.7 m diameter road wheel. As expected, durability testing on the road wheel is more severe, and the beneficial effect of a nylon overwrap is predicted.
Teff could contribute to the Sustainable Goals of United Nation’s Goals in low-income areas of Middle East and North Africa
Authors: Golmohamadi Amir , Yazdi Reyhaneh Akbar Nejad , Kita Kenna
Published: February 2020

Several Sustainable Development Goals of the United Nation are directly or indirectly related to nutrition, including SDG1 (no poverty) and SDG2 (zero hunger). Many parts of the Middle East and North Africa (MENA) region are experiencing poverty or suffering from micronutrient (Calcium, Iron, and Vitamin D) deficiencies, which has contributed to a high mortality rate among children and pregnant women. Teff, an old and well-known grain in MENA and a “Super Grain” in developed countries, has a strong potential to be utilized in food product development activities in MENA. These new products can be produced by local scientists and be sold domestically or internationally. The aim of this short communication is to review the limitations and opportunities that exist in the process of food product development with Teff. Several Sustainable Development Goals of the United Nation are directly or indirectly related to nutrition, including SDG1 (no poverty) and SDG2 (zero hunger). Many parts of the Middle East and North Africa (MENA) region are experiencing poverty or suffering from micronutrient (Calcium, Iron, and Vitamin D) deficiencies, which has contributed to a high mortality rate among children and pregnant women. Teff, an old and well-known grain in MENA and a “Super Grain” in developed countries, has a strong potential to be utilized in food product development activities in MENA. These new products can be produced by local scientists and be sold domestically or internationally. The aim of this short communication is to review the limitations and opportunities that exist in the process of food product development with Teff.
Taxonomic significance of pollen morphology in Succisa and Succisella
Authors: Tsymbalyuk Zoya M. , Mosyakin Sergei L. , Nitsenko Lyudmila M.
Published: February 2020

Pollen morphology of representatives of the genera Succisa and Succisella in the flora of Ukraine was studied using light and scanning electron microscopy. Pollen grains in both taxa were tricolpate, prolate, rarely oblate-spheroidal or spheroidal; large-sized. Their outline in polar view was subcircular, rarely trilobate, in equatorial view elliptical or rarely circular. Colpi short, of variable width, margins irregular with distinct, narrow margo, and blunt or acute ends. Exine sculpture was echinate-microechinate. The revealed characteristics of pollen grains are taxonomically significant at the generic and specific levels, and they can be used in pollen analysis. Palynomorphological data are consistent with the results of recent molecular phylogenetic studies. Data on pollen morphology also confirm taxonomic circumscription of Succiseae V. Mayer & Ehrend. Pollen grains in Succiseae are characterized by a tricolpate aperture type, which was probably ancestral in Dipsacaceae s. str.
Histochemical Staining of Acetylcholinesterase in Carnolian Honeybee (Apis mellifera carnica) Brain after Chronic Exposure to Organophosphate Diazinon
Authors: Glavan Gordana
Published: February 2020

Organophosphate insecticides are known to inhibit the activity of enzyme acetylcholinesterase. They affect olfactory learning and memory formation in honeybees. These insecticides cause mushroom body inactivation in honeybees, but their influence on other brain regions involved in olfactory perception and memory is unknown. The goal of this study was to study the effects of organophosphate insecticide diazinon on carnolian honeybee (Apis mellifera carnica) acetylcholinesterase activity in the olfactory brain regions of antennal lobe, mushroom body and lateral procerebrum (lateral horn). The lamina, medulla and lobula of optic lobes were also analyzed. The level of acetylcholinesterase activity was visualized using the histochemical staining method. Densitometric analysis of histochemical signals indicated that diazinon inhibited acetylcholinesterase activity only in the lip of calyces of mushroom body, but not in other analyzed olfactory regions, antennal lobe and lateral procerebrum. The visual brain system optic lobes were also unaffected. This is in accordance with the literature reporting that mushroom body is the main brain center for olfactory learning and memory formation in honeybees.
Preparation of ternary (35 – x)Sb2O3–xBi2O3–65P2O5 glasses for lead-free glass application
Authors: Li Yu-Ting , Zhang Jing-Jing , Wang Zhi-Qiang , Xu Fei-Long , Lin Hai
Published: February 2020

Glasses composed of ternary components (35 – x)Sb2O3–xBi2O3–65P2O5 (0 ⩽ x ⩽ 20 mol%) have been prepared and investigated as a potential alternative to lead-free glass for low temperature applications. Their structural properties were studied by Infrared Spectroscopy IR and Differential Thermal Analysis DTA. Results from the IR showed that Sb3+ and Bi3+ were responsible for glass network structure, which was supported by the diversification of density ρ and molar volume Vm with an increasing amount of Bi2O3. Glass transition temperature Tg, thermal stability, and coefficient of thermal expansion increased after substitution of Bi2O3 for Sb2O3 within the range of 0 mol% to 20 mol%. The water durability decreased and then increased; it could be attributed to the corrosion resistant P–O–Sb bonds. A typical sample of 25Sb2O3–10Bi2O3–65P2O5 possesses excellent properties and can be a promising candidate for further applications.
From Decoding a Graph to Processing a Multimodal Message: Interacting with data visualisation in the news media
Authors: Engebretsen Martin
Published: February 2020

Data visualisation – in the forms of graphs, charts, and maps – represents a text type growing in prevalence and impact in many cultural domains; education, journalism, business, PR, and more. Research on data visualisation reception is scarce, particularly that related to interactive and dynamic forms of data visualisation in digital media. Taking an approach inspired by grounded theory, in this article I investigate the ways in which young students interact with data visualisations found in digital news media. Combining observations from reading sessions with ten in-depth interviews, I investigate how the informants read, interpreted, and responded emotionally to data visualisations including visual metaphors, interactivity, and animation.
Effect of Health Coaching Approach Based on Motivational Interview on Improving Undesirable Nutritional Habits of Housewives
Authors: Abdolahpour Esmat
Published: February 2020

Background and aims:Nutrition disorders are a common risk factor for many clinical disorders, and effective methods for resolving it are motivational interviewing methods that can be useful in encouraging people to promote lifestyle. In recent years, motivational interviews have come up with community health and often people in need of a change in nutritional habits are so vast that they can maintain their health.

Material and method:This interventional study was carried out on all housewives referring to Mazdak Health home. They were selected by simple sampling method. The sample size was 35 in each subgroup. Food intake was assessed by a feed frequency questionnaire (FFQ) and the energy consumption in kilocalories per day was calculated using Nutritionist 4 software. Using SPSS18 and Chi-square tests, the exact test Fisher, T and Independent Tests, Mann-Whitney, and Wilcoxon were analyzed.

Results:The mean score of healthy nutrition index after intervention was significantly different in intervention and control groups (p-value = 0.004). Also, in whole grain (p-value = 0.001), dairy (p-value = 0.01) Fruits (p-value = 0.01), vegetables (p-value = 0.003) had a significant difference between the mean of intervention and control groups after intervention. There were no significant differences between the other indices after the intervention in the intervention and control groups.

Conclusions:The intervention has been effective and generally increases the index of healthy nutrition index after intervention. But on components of dairy, sodium, refined grains, absent calories, proteins have not had any effect.
The Relative Risk of Developing Type 2 Diabetes Mellitus in Young Adults with Schizophrenia Treated with Different Atypical Antipsychotic
Authors: Cason Nicolae-Marius , Babeș Petru Aurel , Béres Enikő , Babeș Katalin
Published: February 2020

Background and aim: While the link between antipsychotic treatment and metabolic adverse events, including type 2 diabetes mellitus (T2DM) are clear in adults with schizophrenia, in young this association is not so well studied although the use of secondgeneration antipsychotics (SGA) is more and more frequent.

Material and methods: The local diabetes register was compared with the list of all registered young adults (18-35 years) with schizophrenia 2 years retrospective and 2 years prospective. Cumulative incidence, rate of incidence and relative risk was calculated knowing the number of persons in this age group within this region.

Results: Cumulative incidence for exposed group was 0.7% with a rate of incidence of 6.27 (95%CI: 4.1-10.5) per 1,000 patientyears, when in normal population was 0.2%, respectively 2.01 (95%CI: 0.72-3.79). This means a relative risk of 3.4736 (95%CI: 1.79-6.72), p=0.0002 and NNH=202 (95%CI: 134-404). Multivariate analysis showed that gender male (OR=1.83; 95%CI: 0.9-2.7; p=0.002) and olanzapine prescription (OR=4.76; 95%CI: 1.7-7.7; p=0.0001) were independent risk factors for T2DM.

Conclusions: The metabolic risk should be taken in account every time introducing or changing a SGA in young schizophrenic patient, balancing the benefits and negative metabolic effects (especially with olanzapine). Healthy nutrition and physical activities are necessary components of these patients lifestyle to avoid early onset of T2DM.
Documentation of fungal endophytes of black pepper (Piper nigrum L.) and their seed transmission studies
Authors: Sreeja K , Anandaraj M , Suseela Bhai R
Published: February 2020

The present study envisaged to document the endophytic fungal association with black pepper through a series of in vitro and in planta investigations. Black pepper was found to harbour endophytic fungal flora belonging to the genera Alternaria, Acremonium, Aspergillus, Cladosporium, Chaetomium, Curvularia, Colletotrichum, Fusarium, Humicola, Paecilomyces, Rhizoctonia, Phoma and non-sporulating forms. Further, it was found that the endocarp of black pepper seed is free from culturable endophytic fungi. This was evident from the absence of culturable fungi in in vitro grown black pepper seedlings. The growth of fungi from the seedlings grown under green house conditions reveal that the fungal endophytes establish from fungal propagules falling on the (test) plants that may enter the plant tissues as back ground inoculum and grow as endophyte. This was also supported by the study that the type of endophytic fungi that harbour black pepper plants varied with geographical locations from where the samples were collected.
Genotype x environment interaction and stability of indigenous coriander (Coriandrum sativum L.) genotypes for seed yield in different agro-climatic zones of Chhattisgarh
Authors: Sawargaonkar S L , Singh A K , Tiwari J , Singh K P , Sao A , Paraye P M , Painkra S K , Rathia G R , Sahu S , Rao S S , Sarawagi A K , Sharma R N , Bajpai R K , Nirmal Babu K
Published: February 2020

The present study was conducted to find out the stability and yield performances of 13 genotypes of indigenous coriander (Coriandrum sativum L.) evaluated in different agro climatic zones of Chhattisgarh. The trials were laid out in a Randomized Block Design (RBD) with three replications at three locations for three years resulting in nine environments (Genotype × year interactions). The genotypes and G × E interactions revealed significant differences at p <0.01 for seed yield indicating varieties and testing environments were distinct from each other. Additive main effects and multiplicative interaction analysis (AMMI-biplot) indicated that the yield performances of indigenous coriander genotypes were highly affected by the environments. The first two principal component axes (PCA 1 and PCA 2) were significant and they explained 67% of the total genotype x environment interaction of which 42.4% and 24.6% were represented by PCA 1 and PCA 2, respectively. A biplot generated using genotypic and environmental scores of the first two AMMI components demonstrated that genotype with larger PCA 1 and lower PCA 2 scores were high yielding and stable genotypes and genotypes with lower PCA 1 and larger PCA 2 scores were low yielding and unstable cultivars in tested locations. The genotype GC 5 C-101 (ICS 4) showed higher grain yields (16.35 q ha-1) over grand mean (13.03 q ha-1) and also had the minimum PCA 1 score, minimum AMMI stability value (ASV) and yield stability index (YSI). Therefore genotype ICS 4 (Chhattisgarh Shri Chandrahasini Dhaniya -2) showed wider stability across different agro climatic environments of Chhattisgarh.
kGCN: A Graph-Based Deep Learning Framework for Chemical Structures
Authors: Kojima Ryosuke , Ishida Shoichi , Ohta Masateru , Iwata Hiroaki , Honma Teruki , Okuno Yasushi
Published: February 2020

Deep learning is developing as an important technology to perform various tasks in cheminformatics. In particular, graph convolutional neural networks (GCNs) have been reported to perform well in many types of prediction tasks related to molecules. Although GCN exhibits considerable potential in various applications, appropriate utilization of this resource for obtaining reasonable and reliable prediction results requires thorough understanding of GCN and programming. To leverage the power of GCN to benefit various users from chemists to cheminformaticians, an open-source GCN tool, kGCN, is introduced. To support the users with various levels of programming skills, kGCN includes three interfaces: a graphical user interface (GUI) employing KNIME for users with limited programming skills such as chemists, as well as command-line and Python library interfaces for users with advanced programming skills such as cheminformaticians. To support the three steps required for building a prediction model, i.e., pre-processing, model tuning, and interpretation of results, kGCN includes functions of typical pre-processing, Bayesian optimization for automatic model tuning, and visualization of the atomic contribution to prediction for interpretation of results. kGCN supports three types of approaches, single-task, multi-task, and multimodal predictions. The prediction of compound-protein interaction for four matrixmetalloproteases, MMP-3, -9, -12 and -13, in the inhibition assays is performed as a representative case study using kGCN. Additionally, kGCN provides the visualization of atomic contributions to the prediction. Such visualization is useful for the validation of the prediction models and the design of molecules based on the prediction model, realizing “explainable AI” for understanding the factors affecting AI prediction. kGCN is available at https://github.com/clinfo/kGCN.
Potential Inhibitors Against Papain-like Protease of Novel Coronavirus (COVID-19) from FDA Approved Drugs
Authors: Arya Rimanshee , Das Amit , Prashar Vishal , Kumar Mukesh
Published: February 2020

The cases of 2019 novel coronavirus (COVID-19) infection have been continuously increasing ever since its outbreak in China last December. Currently, there are no approved drugs to treat the infection. In this scenario, there is a need to utilize the existing repertoire of FDA approved drugs to treat the disease. The rational selection of these drugs could be made by testing their ability to inhibit any COVID-19 proteins essential for viral life-cycle. We chose one such crucial viral protein, the papain-like protease (PLpro), to screen the FDA approved drugs in silico. The homology model of the protease was built based on the SARS-coronavirus PLpro structure, and the drugs were docked in S3/S4 pockets of the active site of the enzyme. In our docking studies, fifteen FDA approved drugs, including chloroquine and formoterol, bind the target enzyme with significant affinity and good geometry, suggesting their potential to be utilized against the virus.
Comparison of surgical treatment results of critical limb ischemia and analysis off actors influencing the outcome of surgical treatment
Authors: Beňo P. , Rusňák M. , Štefanič P. , Kopolovets I.
Published: February 2020

Objective. To evaluate the results of surgical treatment of critical limb ischemia in two specialized vascular centers.
Materials and methods. The results of surgical treatment of 202 patients with critical lower limb ischemia, which were operated in two specialized vascular centers: I Group (76 patients) -ClinicofVascularSurgery at the Military Hospital, Ruzomberok,Slovak Republic; II Group (126 patients) -ClinicofVascularSurgery, EastSlovakInstituteofCardiovascularDiseases, Kosice, Slovak Republic.
Results.The patency of arterial reconstructions in I Group was: the femoro-supragenicular segment: 1 year -83%, 3 years - 73%;the infragenicular segment: 1 year - 68%, 3 years - 52%. In II Group -the femoro-supragenicular segment: 1 year - 91%, 3 years - 82%;the infragenicular segment: 1 year - 72%, 3 years - 64%.
Conclusion.The patency of arterial reconstructions during the first year in both vascular centers was without statistical difference. The femoro-supragenicular reconstructions had the best patency over three years (> 70%). The following factors influenced the duration of arterial reconstructions: the type of graft used, diabetesmellitus, smoking.
Peculiarities of course of an acute cholecystitis in patients with obesity
Authors: Tkachuk O. V. , Chanturidze A. A. , Reiti A. O. , Kebkalo A. B.
Published: February 2020

Objective. To study peculiarities of course of an acute cholecystitis, development of complications and mortality in patients with obesity.
Materials and methods. The data, concerning 387 patients, suffering an acute cholecystitis, were analyzed retrospectively. There were following criteria of the patients’ exclusion from the investigation: chronic cholecystitis or is acute phase; age lesser than 18 yrs; incomplete spectrum of investigations performed; obturation jaundice, including those, suffering oncological disease; excessive body mass.The diagnosis was confirmed by application of ultrasonographic investigation and CT.
Results. Of 387 patients, suffering an acute cholecystitis, 208 (53.7%) had obesity (the investigated group). In a control group there were 179 (46.3%) patients. The patients, suffering obesity, were younger than patients in  a control group: (47.53 ± 2.04) and (54.5 ± 1.63) yrs, accordingly (p=0.01, α=0.05). In the investigation group there were in 1.2 times more women. In the patients with obesity operative intervention was longer - (91.3 ± 0.65) min, than in patients of a control group - (73.7 ± 0.75) min (p=0.001; α=0.05). Potent positive correlational link between two variables (r=0,9078) was established with the determination coefficient R2=0.8213; p=0.001. This have witnessed, that with the 95% CI the body mass index in up to 82% patients the operative intervention variety depends on.
Conclusion. In the patients with obesity the operative intervention duration and the conversion rate enhances, as well as the stationary stay and the postoperative wounds infectioning rate, increasing the treatment expenses. In the patients with obesity mortality is a statistically nonsignificant.
Miniinvasive video-assisted interventions on the thyroid and parathyroid glands
Authors: Grubnik V. V. , Parfentiev R. S. , Kosovan V. M.
Published: February 2020

Objective. To study the efficacy of miniinvasive video-assisted interventions on the thyroid and parathyroid glands. Materials and methods. In a frame of the investigation accomplished in 2012-2018 yrs 50 patients were operated for nodular goiter (40) and primary hyperparathyrosis with solitary adenoma of a parathyroid gland (10). In all the patients miniinvasive video-assisted interventions were performed in accordance to procedure, proposed by P. Miccoli. Results. A pain syndrome was minimal in all the patients. Stable paresis of nn. Recurrens and parathyrosis were not observed. Transitory paresis of n. Recurrens have occurred in 2 patients. The wound infection was absent. In all the patients with primary hyperparathyrosis the calcium content have lowered down to normal or subnormal value. Stationary stay after miniinvasive operations have been reduced down to (2.2 ± 0.3) bed-days, while after open operations they constituted (5/7 ± 1.2) bed-days. While further follow-up of the patients during one year the disease recurrence was not registered. Excellent cosmetic result was obtained in majority of the patients. In 3 of them only keloid cicatrices have formatted, causing  a cosmetic effect lowering. Conclusion. The procedure for miniinvasive video-assisted interventions on thyroid gland was proposed by P. Miccoli, and is still actual. It may be applied also in patients with primary parathyrosis and solitary adenoma of parathyroidal gland. But the patients must be thoroughly selected  for this operative interventions.
Interactive alignment in Polish: A CMC-based study
Authors: Placiński Marek
Published: February 2020

One of the focuses of psycholinguistic research has been producing and understanding language (c.f. Griffin and Ferreira 2006; Pardo and Remez 2006). Until very recently (Bock 1986), such research primarily concerned understanding or producing isolated sentences or words. However, using language in isolation constitutes a minor part of how people interact. In response, Pickering and Garrod proposed the interactive alignment model, which is supposed to explain the processes which are engaged in comprehension and production in dialogue. This paper addresses the issue of the interactive alignment model in Polish in computer-mediated communication. The article first outlines the theoretical background for the research by describing the semantic and syntactic aspects of language production and comprehension. Next, it introduces the concept of the interactive alignment model and lays down its main tenets. Finally, the paper describes the research method and the qualitative analysis of the results of the experiment conducted for the purposes of the study.
Comparison of anthropometric characteristics between world tour and professional continental cyclists
Authors: Miller Joshua , Susa Kyle
Published: February 2020

This study analyzed the physical characteristics of the World Tour (WT) and Professional Continental (PC) cyclists during the 2018 racing season. Seven hundred sixty-three professional riders (27.9 +4.2 years, 1.81 +0.06 m, 68.6 +6.33 kg) were compared for physical characteristics (i.e. age, height, and body mass). All riders were classified within specialties based upon UCI points ((grand champion (GC), sprinter (S), time trialists (TT), one-day racer (OD)) earned during the previous season. As expected there were differences between the rider’s specialty as well as the different elite divisions of riders. Further results showed that there was no difference in Body Mass Index (BMI; kg.m2) in all riders, however, TT riders in the WT had a significant difference in body surface area (BSA) and frontal area (FA) when compared to the TT riders in the PC division. In conclusion, the present study identified specific physical characteristic differences between the different types of professional cyclist levels of riders (WT vs. PC) and within their specialty.
STRATEGI PENGEMBANGAN WILAYAH EKONOMI KABUPATEN BANGKALAN
Authors: Pratama Ahmad Herlyasa Sosro , Rustiadi Ernan , Syaukat Yusman
Published: February 2020

ABSTRACT               Bangkalan City became one of the regional activities of regional centers in Gerbangkertosusila (Gresik-Bangkalan-Mojokerto-Surabaya-Sidoarjo-Lamongan) Regional Units with Surabaya as its center. Therefore, to compensate for development with other SWP areas. In general, the purpose of this study is to formulate the strategy for the development of the existing economic region in Bangkalan regency. through Input-Output analysis (I-O) and Analithical Hierarchy Processs (AHP). There are 4 steps identified through the I-O analysis, including the linkages of economic sectors, key sectors, economic sector multipliers, and investment impacts. The I-O analysis is performed as an alternative basis for the strategy that will be later responded by the AHP analysis. The alternative strategic priorities generated through AHP analysis will be translated into policy recommendations in determining the priority of investment sector economic development in Bangkalan District,Keywords: Regional development, Input-Output, economic sector, investment polic ABSTRAK            Kota Bangkalan menjadi salah satu pusat kegiatan skala regional kabupaten dalam Satuan Wilayah Pembangunan (SWP) Gerbangkertosusila (Gresik-Bangkalan-Mojokerto-Surabaya-Sidoarjo-Lamongan) dengan Surabaya sebagai pusatnya. Maka dari itu, untuk mengimbangi pembangunan deagan daerah - daerah SWP lainnya. Secara umum, tujuan kajian ini adalah merumuskan strategi pengembangan wilayah ekonomi yang ada di Kabupaten Bangkalan. melalui analisis Input-output (I-O) dan Analithical Hierarchy Processs (AHP). Terdapat 4 langkah diidentifikasi melalui analisis I-O, antara lain keterkaitan sektor ekonomi, sektor kunci, pengganda sektor ekonomi, dan dampak investasi. Analisis I-O dilakukan sebagai dasar alternatif strategi yang nanti akan direspondensi oleh analisis AHP. Prioritas alternatif strategi yang dihasilkan melalui analisis AHP akan diterjemahkan menjadi rekomendasi kebijakan dalam menentukan prioritas pengembangan investasi sektor ekonomi di Kabupaten Bangkalan,Kata Kunci : Pengembangan wilayah, Input-Output, sektor ekonomi, kebijakan investasi
PENGEMBANGAN BIODIESEL KELAPA SAWIT DI INDONESIA
Authors: Falatehan Ahmad Faroby , Siswanto A. Dwi
Published: February 2020

Palm oil has become the flagship product in the plantation business in Indonesia. Currently, Indonesia has become the country with the largest palm oil production capacity in the world. With the production capability, the opportunities to diversify energy made from palm oil to be possible.This study analyzes using secondary data to determine the extent of the potential of palm oil as the main source of raw material for biodiesel in Indonesia. The results of the analysis states that the production capacity and expansion of palm oil a very massive, energy diversification is a relevant step and is feasible. The role of government through export levy tariff policy in determining the oil consumption in the interest of the domestic market.Key word : Palm oli, Biodiesel, CPO, flagship productABSTRAK Kelapa sawit telah menjadi produk unggulan dalam bisnis perkebunan di Indonesia. Saat ini Indonesia telah menjadi negara dengan kemampuan produksi kelapa sawit terbesar di dunia. Dengan kemampuan produksi tersebut maka peluang untuk melakukan diversifikasi energi berbahan baku kelapa sawit menjadi sangat mungkin. Analisis kajian ini dilakukan dengan menggunakan data sekunder untuk mengetahui sejauhmana potensi kelapa sawit sebagai sumber utama bahan baku biodiesel di Indonesia. Hasil analisis menyatakan bahwa dengan kemampuan produksi dan perluasan lahan kelapa sawit yang sangat massif, diversifikasi energi merupakan langkah yang relevan dan sangat mungkin dilakukan.Peran pemerintah melalui kebijakan tariff pungutan ekspor ikut menentukan konsumsi sawit bagi kepentingan pasar domestik.Kata kunci : Kelapa Sawit, Biodiesel, CPO, produk unggulan
UPAYA MENINGKATKAN RASA INGIN TAHU DAN PRESTASI BELAJAR BAHASA JAWA MATERI MENULIS AKSARA JAWA MELALUI METODE STRUKTURAL ANALITIK SINTETIK
Authors: Widiasih Hening Setio
Published: February 2020

The research is supported by the low curiosity and learning achievement of the students for the fifth graders SDN 2 Kaligondang. It aims: to improve the curiosity and learning achievement of Javanese Language on the topic of writing Javanese letters through synthetic analytic structural (SAS). The subject covered the fifth graders of SDN 2 Kaligondang consisted of 23 students. This classroom action research consisted of 2 cycles and each cycle had 2 meetings (per meeting included 2 teaching hours). The procedures included planning, acting, observing and reflecting. The data were collected by observation sheets of the teacher and students. The curiosity and learning achievement were gathered from test and questionnaire by the end of the cycle. The first cycle showed the mean of students' curiosity 28.51%. The learning achievement in the first cycle was 60.86% with the mean 68.65. The second cycle showed that the mean of students' curiosity was 34.13. The learning achievement was 86.95% with the mean 80.47. Thus, it could be drawn that Synthetic Analytic Structural could improve students' curiosity and learning achievement for the fifth graders SDN 2 Kaligondang
Evaluasi Kekuatan ConcBlock Dengan Agregat Halus dan Agregat Kasar dari Tempurung Kelapa
Authors: Bintoro Agnes Yuanita , Limantara Arthur Daniel , Winarto Sigit
Published: February 2020

The growing age of the utilization of production can be processed into an environmentally friendly material. It's Rotary to save costs for doing construction activities. Therefore, using fuel for mixed materials, you can reduce the cost and also can produce as an environmentally-friendly road pavement can also absorb air into the soil, so that road pavement is not easily damaged.The purpose of this research is to know the result of concrete from fine aggregate and a coarse aggregate of coconut shell. The object used is the size of a cube with size 15x15x15 cm of 20 samples, consisting of 5 samples for variation. A sample of betonuks at 28 days concrete age.The results of concrete compressive strength and absorption of concrete using a mixture of fine aggregate and aggregate at 28 days for each variable are:Variation 0% obtained compressive strength equal to 18,5 Mpa and absorption power of concrete equal to 13,60%.Variations of 20% coconut shell and 15% of shell powder obtained strong pressure of 11.4 MPa and absorption of 11.69%.Variation of 25% coconut shell and 20% of shell powder obtained strong pressure of 7.6 MPa and absorption of 11.64%.Variations of 30% coconut shell and 25% shell powder obtained strong pressure of 6.7 Mpa and absorption of 10.17% concrete.From these results, it can be concluded that the concrete used is a mixture and a coarse aggregate of coconut shell and kerosene.Keywords: Compressive strength of concrete, absorption, aggregate mix, shell coconut, shell powder, concblock
PERBANDINGAN KEKUATAN BETON DENGAN CAMPURAN DRAMIX STEEL FIBER DAN TULANGAN WIREMESH PADA RIGID PAVEMENT (Comparison of the Strength of Concrete with a mixture of Dramix Steel Fiber and Wiremesh Reinforcement on Rigid Pavement)
Authors: Guntur A Two Puji , Cahyo Yosef , Winarto Sigit
Published: February 2020

ABSTRACTConcrete has a weakness that is having a low tensile strength and brittle so that the concrete is given steel reinforcement to anticipate it. In this study, the concrete mixture was added with dramix steel fiber. This addition was carried out to study and determine the effect of dramix steel fiber on compressive strength, flexural strength on normal quality concrete with the addition of 0%, 10%, 20% and 30% in compressive loads. Compressive strength specimens in the form of cylinders with a diameter of 15 cm and a height of 30 cm and bending strength test specimens in the form of blocks with a length of 60 cm, width of 15 cm and height of 15 cm. Testing is done after 28 days. Concrete with the addition of dramix steel fiber is 30% more capable of producing a higher compressive strength than the others. The addition of dramix steel fiber resulted in an average compressive strength of 0%, 29.07 MPa, 10%, 29.33 MPa, 20%, 29.40 MPa, 30%, 29.58 MPa. For the highest flexural strength of concrete in the 15/15/60 beam sample, that is in the concrete mixture and the addition of dramix steel fiber of 5.44 MPa, it is higher than the addition of reinforcement iron m8, which is 4.96 MPa.Keywords:Dramix Steel Fiber, compressive strength, concrete flexural strength, m8 wiremesh
STUDI ANALISA PERENCANAAN PERKERASAN LENTUR DAN RENCANA ANGGARAN BIAYA (PADA PROYEK JALAN RUAS JALAN TEMBELENGAN–DURJAN KABUPATEN SAMPANG)
Authors: Aziz Mishbahul , Winarto Sigit , Setianto Poernomo Yosef Cahyo , Candra Agata Iwan
Published: February 2020

There was a build-up of lumps of sand on the road, precisely Tambelang-Durjan. This build-up of sand chunks occurs because many of the piled sand hauling trucks that pass on the road is obstructed because the road section has been damaged (potholes) and is unfit for passage, resulting in obstruction of traffic flow. In addition, the width of the section is not in accordance with the technical requirements of the 2011 Government Regulation. Therefore, it requires a flexible pavement re-planning and a Cost Budget Plan for land transportation lines, so that motorist access is comfortable. Planning flexible pavement using Laston with a planning age of 10 years obtained flexible pavement thickness, namely 4 cm thick AC-WC, 6 cm thick AC-BC, and 40 cm of Upper Foundation Layers (LPA) with the estimated size of the Budget Plan The cost of the flexible pavement construction of Tambelang- Durjan of Sampang Regency with a length of 1,145 km in the amount of Rp 5,744,585,463.00Terjadi penumbukan bongkahan pasir urug tepatnya di ruas jalan Tambelangan-Durjan. Penumpukan bongkahan pasir ini terjadi karena banyak truk pengangkut bongkahan pasir urug tersebut yang melintas pada jalan itu terhambat karena ruas jalan mengalami kerusakan (berlubang) dan tidak layak dilalui, sehingga  yang mengakibatkan terhambatnya arus lalu lintas. Selain itu lebar ruas tidak sesuai dengan persyaratan teknis Peraturan Pemerintah tahun 2011. Oleh karena itu, memerlukan perencanaan ulang perkerasan lentur dan Rencana Anggaran Biaya untuk jalur transportasi darat supaya akses pengendara nyaman. Perencanaan perkerasan lentur menggunakan Laston dengan umur rencana 10 tahun didapatkan tebal perkerasan lentur yaitu AC-WC setebal 4 cm, AC-BC setebal 6 cm dan Lapis Pondasi Atas (LPA) setebal 40 cm dengan besar perkiraan Rencana Anggaran Biaya pembangunan perkerasan lentur ruas Tambelangan-Durjan Kabupaten Sampang sepanjang 1,145 km sebesar Rp 5.744.585.463,00.