bluuebunny/crossref_metadata_2025 huggingface dataset:
Apneia obstrutiva do sono e insuficiência cardíaca pré-clínica em pacientes obesos no município de Teixeira de Freitas-BA
Authors: Barbosa Gabriela de Azevedo , Lima Clara Monica Figueredo de
Published: August 2023

Introdução: A apneia obstrutiva do sono (AOS), uma doença crônica, progressiva, com alta mortalidade e morbidade, que tem sido associada às doenças cardiovasculares, entre elas, a insuficiência cardíaca, acometendo principalmente obesos. Objetivo: reconhecer associação dos pacientes obesos e portadores AOS identificados pela PSG que apresentam alterações estruturais e funcionais em pacientes sem Insuficiência Cardíaca (IC) atendidos pela Clínica do Sono em Teixeira de Freitas-BA. Metodologia: primeiramente, foi feita a seleção de pacientes pela Clínica do Sono na cidade de Teixeira de Freitas-BA, aplicação dos questionários Questionário Sociodemográfico e de Saúde, e o Estado de Saúde (SF-36). Em segundo lugar, foi realizada uma avaliação médica, com anamnese detalhada e Exame Físico, buscando avaliar a obesidade do paciente e averiguar se o paciente já possuía IC. Posteriormente, foi feita uma polissonografia (PSG). Os dados obtidos foram dispostos em planilhas eletrônicas e analisados estatisticamente pelo Software StatSoft. Inc., USA. Resultados Esperados: viu-se que o IMC aumenta a taxa de incidência de AOS.
Pembinaan Profesionalisme Guru untuk Meningkatkan Kemampuan Menerapkan Model Pembelajaran yang Efektif
Authors: Darnata Darnata
Published: August 2023

Hasil pengamatan menunjukkan bahwa guru cenderung

kurang kreatif dan inovatif dalam proses pembelajaran, terbukti dari

pengakuan guru-guru yang menjadi subjek dalam penelitian dengan

menjadikan ceramah sebagai pilihan utama strategi mengajarnya. PTS

ini dilaksanakan berdasarkan tahapan-tahapan sebagai berikut: “(1)

merencanakan tindakan, (2) melaksanakan tindakan, (3) melaksanakan

observasi, (4) melakukan refleksi.. Pada siklus I tingkat kemampuan para

guru MI Al-Hidayah GUPPI pada dalam memahami terhadap penerapan

model pembelajaran yang efektif setelah adanya tindakan menunjukkan

skor rata-rata yaitu: Kategori baik mencapai rata-rata 40%; Kategori

cukup mencapai rata-rata 36 %; Kategori kurang mencapai rata-rata 24

%. Pada siklus II tingkat kemampuan para guru MI Al-Hidayah GUPPI

pada dalam memahami terhadap penerapan model pembelajaran yang

efektif setelah adanya tindakan menunjukkan skor rata-rata yaitu:

Kategori sangat baik mencapai rata-rata 62 %; Kategori baik mencapai

rata-rata 16 %; Kategori cukup mencapai rata-rata 16 %.
Farklı bölgelerden selekte edilen bazı kestane çeşit/genotiplerin azot özümleme kapasitesinin değerlendirilmesi
Authors: MÜFTÜOĞLU Başak , AKPINAR Aysegul , MERT Cevriye
Published: August 2023

Azot metabolizması bitkilerin temel fizyolojik süreçlerinden biridir ve büyüme ile doğrudan ilişkilidir. Bitkiler tarafından nitrojen asimilasyonu, topraktan nitratın (NO3–) alınmasını ve nitrite (NO2–) indirgenmesini ve ardından NO2–'nin amonyuma (NH4+) dönüştürülmesini gerektirir. Bunu NH4+’nın organik bileşiklere dahil edilmesi izler. Azot asimilasyonunda anahtar enzim olan nitrat redüktazın (NR) aktivitesi, azot metabolizmasının bir göstergesi olarak kabul edilir. Bitkiler azotu hem nitrat (NO3-) hem de amonyum (NH4+) olarak alabilir, ancak her azot kaynağının absorpsiyon özellikleri bitki türleri arasında farklılık gösterir. Kestane tür ve çeşitlerinin azot özümleme kapasitesi ile ilgili yeterli bilgi bulunmamaktadır. Bu makalede aynı ekolojik koşullar altında yetiştiriciliği yapılan farklı bölgelerde seleksiyon çalışmaları ile öne çıkan dört kestane çeşit/genotipin (‘Alimolla’, ‘Sarıkestane’, ‘N-23-1’ ve ‘Erfelek’) azot özümleme kapasitesindeki vejetasyon döneminde görülen değişimleri değerlendirilmiştir. Çeşit/genotiplerden Mayıs-Ekim ayları arasında aylık alınan yaprak örneklerinde nitrat redüktaz aktivitesi (NRA), toplam nitrojen (N), klorofil ve biyokütle parametreleri saptanmıştır. Örneklerin NRA'sı in vivo teste göre belirlenmiştir. Bu spektrofotometrik yöntem, inkübasyon ortamında nitratın indirgenmesi ile oluşan nitritin (NO2-) absorbansının belirlenmesine dayanır. Sonuçlarımız kestane çeşit/geonotiplerin azot özümseme yeteneğinin birbirinden farklı olduğunu göstermiştir. Bu sonuçlar aynı zamanda klorofil içeriği ve biyokütle gibi diğer parametrelerle de yakından ilişkilidir. Kestane çeşitlerinin fizyolojik özelliklerinin ortaya çıkarılması ve işleyişinin öğrenilmesi açısından bulgularımız önemlidir.
Kahverengi Kokarca [Halyomorpha halys (Hemiptera: Pentatomidae)]’nın Feromon Tuzaklarının Etkinliğinin Belirlenmesi
Authors: ALTANLAR Ercan , TUNCER Celal
Published: August 2023

Kahverengi kokarca (Halyomorpha halys), çok sayıda konukçu bitkide beslenebilen önemli bir istilacı böcek türüdür. Türkiye’deki varlığı ilk kez 2017 de tespit edilmiştir. Feromon tuzakları zararlının hem populasyon izlenmesinde hem de kitlesel yakalamada yaygın bir biçimde kullanılmaktadır. Bu araştırma 2021 yılında (Temmuz-Eylül) Artvin ilinde, zararlıya karşı feromon kaynağının saha etkinliği, 3 farklı tuzak tipinin 3 farklı bitki ekositemindeki yakalama etkinliği ve zararlının bu alanlardaki mevsimsel dağılışını tespit etmek amacıyla yapılmıştır. Fındık, kivi ve mısır alanlarında yürütülen çalışmada Funnel, Bidon ve Yapışkan tuzak olmak üzere 3 farklı tuzak tipi denenmiş, feromon kaynağı olarak Pherocon® trece kullanılmıştır.Feromon kaynağının saha etkinliği feromon olmayan tuzaklarla karşılaştırıldığında, Yapışkan ve Bidon tip tuzaklarda % 100, Funnel tip tuzakta ise % 99,9 olarak belirlenmiştir. Mevsim boyunca en fazla böcek Funnel tuzakta yakalanmış, yakalanan böcek sayısı Funnel, Bidon ve Yapışkan tuzak için sırasıyla 145, 96 ve 99 böcek/tuzak olarak saptanmıştır. Toplam yakalanan böcek sayısı Funnel tuzakta 2912, Bidon tuzakta 1939 ve Yapışkan tuzakta 1982 adet olmuştur. Fındık, Kivi ve Mısır alanlarında mevsim boyunca yakalanan böcek sayısı sırasıyla yaklaşık 35, 48 ve 31 böcek/tuzak olarak belirlenmiştir. Mevsim boyunca Fındık’ta 2080, Kivi’de 2869 ve Mısır’da 1884 adet böcek yakalanmıştır. En yüksek böcek yakalama Eylül ayında gerçekleşmiştir.
The Effects of Plant Density and Shading on Some Agricultural Traits of Salep Orchid (Serapias vomeracea)
Authors: ŞAVŞATLI Yusuf , AKCA Mehmet
Published: August 2023

Serapias vomeracea is a valuable plant from the Orchidaceae family, especially in that its tubers are used to make hot drinks. In this study, the plants were grown in field conditions, and it was investigated in detail for the first time to determine the effect of plant density and shading on some agronomic traits of Serapias vomeracea. The five levels of plant density (20x10 cm, 20x5 cm, 10x10 cm, 10x6.6 and 10x5 cm) and three levels of shading (Control, 55% and 75%) were tested. The plants were harvested for new tubers in full flowering period. As a result of the study, the shading was effective on the dry matter ratio (P
Hand Manifestations of Systemic Diseases: Radiographic Imaging Findings and Approaches
Authors: Poojary Shweta Raviraj , Shekar Sujith , Pradeep Hagalahalli Nagarajegowda , Nanjaraj Chakenahalli Puttaraj , S Prathibha P
Published: August 2023

The hands act as a mirror in many systemic diseases. Identification of a variety of inflammatory, degenerative, congenital, and hematological diseases can be performed by a single hand radiograph which may help start early intervention and prevent morbidity. Endocrinological and metabolic disorders also may demonstrate signs on a hand radiograph. Granulomatous conditions and systemic connective tissue disorders demonstrate characteristic imaging features which may aid the diagnosis. Radiologists should be familiar with the radiographic imaging findings of common systemic disorders because these may be a problem solving tool to aid in diagnosis.
Effects of post-activation protocols based on slow tempo bodyweight squat and isometric activity on vertical jump height enhancement in trained males: a randomized controlled trial
Authors: Koźlenia Dawid , Domaradzki Jarosław
Published: August 2023

This study aimed to establish the effectiveness of slow tempo bodyweight squat combined with an isometric squat (ST-ISO), and an isometric squat alone (ISO), as a post-activation performance enhancement protocol (PAPE) for jump height improvement. The study sample consisted of 41 trained men aged 18–24. The ST-ISO group (n = 17) performed three five-second sets of the maximal voluntary back squat while pushing on an immovable bar and two sets of five repetitions of a slow-tempo (5-0-5-0) body squat immediately after isometry with a 2-m rest interval. The ISO (n = 14) group only performed isometric squats, and the control group (CG; n = 10) performed a 5-min treadmill run at 6 km/h. The countermovement jump (CMJ) height results were analyzed from the baseline and then at 3, 5, 7, and 9 min after the PAPE protocols. The statistical significance was set at p < 0.05. RM-ANOVA revealed differences in the group-minute interaction (F = 2.70; p = 0.0083; η2 = 0.1243), and post-hoc tests demonstrated a significant decrease in CMJ after 5 min in the ISO group (p < 0.0446). The performance of the ST-ISO group markedly decreased in the 3rd and 7th min after PAPE (p = 0.0137; p = 0.0424, respectively), though it improved significantly in the final minute (p < 0.0030). Chi-squared analysis revealed that the ST-ISO group peaked more frequently in the 9th min (X2 = 17.97; p = 0.0214). However, CMJ height improvement did not differ between the PAPE protocols, thus it was close to statistical significance (t = −1.82; p = 0.07; ES = 0.7). The ST-ISO protocol provided jump enhancement, though the deterioration observed in the first minutes after the protocols suggest the rest period after activity requires attention, and the methods need to be individualized.
THE EFFECT OF PERCEIVED RISK, SUBJECTIVE NORM, BRAND REPUTATION ON THE ATTITUDE AND THE INTENTION TO USE DIGITAL BANK SERVICES IN INDONESIA
Authors: Hartono Nicholas Bram Yoevanto , Jaolis Ferry , Wijaya Serli
Published: August 2023

The penetration of internet use in the world and in Indonesia has increased quite significantly in the last five years. This growth has been supported by a number of factors forming positive attitudes (the attitude toward using digital banks) and driving the intentions to adopt digital banking services (the intention to use digital banks), such as perceived risk, brand reputation, and subjective norms. Samples were purposively selected in the age range of 25-76 and the responses to the self-administered questionnaire were processed using SEM-PLS. The results of the research demonstrate that only subjective norms are able to substantially alter the attitude toward and the intentions toward using digital banks. Attitude toward using a digital bank is a key process that partially explains the influence of brand reputation and subjective norms on the intention to use a digital bank.
FAMILY OWNERSHIP MATTERS FOR INVESTORS IN INDONESIA'S MINING COMPANIES
Authors: Purnamawati I Gusti Ayu , Yuniarta Gede Adi , Suwena Kadek Rai , Heryanda Komang Krisna , Hatane Saarce Elyse
Published: August 2023

This study aims to determine the effect of family ownership, financial performance, return on assets, return on equity, liquidity, and capital structure on market value. Secondary data was obtained based on annual reports and financial statements in mining companies listed on the IDX in 2016-2020 through Indonesia Stock Exchange (IDX). Data were obtained from the Bloomberg database. The method used to collect samples is purposive and consists of 35 mining companies in Indonesia. The panel data method was considered appropriate in this study, and multiple regression was used to examine the data. The results show that total assets and return on assets positively affect market value. The ratio of return on equity and liquidity in financial performance and capital structure has no significant effect on market value. The existence of family ownership is favourable for a firm’s market value. The sample in this study was limited to the manufacturing sector. This industry was chosen because its market value is quite volatile and family ownership is quite large. On average there are 40% of the total observations are family-owned companies. The interesting findings in this study are that family ownership does matter in gaining the investors’ attention.
HUMAN RIGHTS DISCLOSURE ON PANDEMIC REPORTING PERIOD IN INDONESIA
Authors: Tjondro Elisa , Sugianto Andrew , Allan Allan , Kusuma Richard
Published: August 2023

The study aims to explain the effect of the pandemic reporting period, non-executive board, audit committee, and family ownership on increasing human rights disclosure. The pandemic of COVID-19 has created an economic pandemonium globally, including in Indonesia. Indonesia's independent agency of the FSA issued a public notice in March 2020, extending the reporting period to May 2020, extending two months. This extension has created an opportunity for companies to announce their human rights practice disclosure facing the oncoming turbulent times. UNGP-BHR and the Indonesian State Law No. 39 of 1999 about Human Rights are used as the disclosure index checklist. Our study uses 345 non-financial sectors listed on the Indonesia Stock Exchange (IDX) with an observation period of 2017 - 2019. The data analysis technique is panel regression. The result shows that the pandemic reporting period, the non-executive board, and the audit committee have positively affected human rights disclosure. The 2019 annual report recorded that human rights disclosure was higher in the pandemic reporting period than in the 2017 and 2018 annual reports. This research implies that companies consider the oncoming turbulent times caused by the pandemic in disclosing last year's human rights disclosure. The non-executive board and the audit committee have a spirit of UNGPs that encourages companies to implement human rights in their operations.
THE EFFECT OF CELEBRITY ENDORSEMENT ON PURCHASE INTENTION
Authors: Tarigan Ruth Srininta , Tandung Juliana Caesaria , Sutrisno Ansell Kevyn , Viriyani Viriyani
Published: August 2023

The utilization of celebrity endorsement as a marketing strategy has gained widespread popularity across various industries, including the electronic industry. The objective of this study is to assess the correlation between celebrity endorsement and purchase intention, specifically through brand image. The analysis compares the relationship between variables at two levels: industry and brand, each at varying levels of maturity. Results indicate that at the industry level, brand image plays a positive mediating role in the relationship between celebrity endorsement and purchase intention, despite a negative direct relationship between the two. At the brand level, celebrity endorsement has a negative impact on purchase intention for Samsung, while exhibiting no significant effect on Vivo brand. However, brand image positively mediates the relationship between the two. Furthermore, multigroup analysis reveals that the difference in effect between the two brands is not statistically significant.
FINANCIAL MANAGEMENT BEHAVIOR AMONG STUDENTS: THE INFLUENCE OF DIGITAL FINANCIAL LITERACY
Authors: Clarence Johann , Pertiwi Dewi
Published: August 2023

The goal of this study is to investigate how digital financial literacy affects the financial management behavior of students who use digital banking services in Surabaya. Primary data were obtained from questionnaires distributed to students in Surabaya. Using the SmartPLS 4 program, the partial least square structural equation modeling (PLS-SEM) technique was employed for data analysis in this study. The findings of this study indicate that students in Surabaya who utilize digital banking services have a substantial impact on their saving behavior when they are financially literate, digital financial literacy has a significant effect on the spending behavior of students who use digital bank services in Surabaya, digital financial literacy has a significant effect on investment behavior of students who use digital bank services in Surabaya. In short, this research can contribute to helping students in Surabaya to deepen their understanding of digital financial literacy.
Acid‐Responsive Nanoregulators Elicit Hydrogen Sulfide‐Mediated Tumor Oxygenation and Selective Sonosensitization for Hypoxic Tumors
Authors: Yu Qi , Zhang Qin , Zhou Yujing , Yan Shan , Li Juan , Yang Ceyao , Xu Jie , Li Cao , Zhang Chao , Sun Yao
Published: January 2025

Oxygen (O2) tension within a tumor is considered a hallmark of sonodynamic therapy (SDT). Herein, multifunctional nanoregulators, CMCS‐Au‐SrS (CAS), are reported, which are assembled by carboxymethyl chitosan(CMCS) tethered gold nanoclusters (Au NCs) as sonosensitizers and sulfurate donors strontium sulfide nanoparticles (SrS NPs), to evoke selective SDT in hypoxic tumors. CAS possess tumor‐acidity responsiveness to form large‐size aggregated Au NCs with shortened bandgap so that effectively induce powerful reactive oxygen species generation. On the other hand, acidity triggers the degradation of SrS NPs and release hydrogen sulfide (H2S), evoking tumor oxygenation to overcome hypoxia. This in junction with the accelerated sonosensiting ability boosts amplified SDT efficacy. More importantly, specific glycolysis induced acidification leads to CAS selectively accumulated in cancer cells, further guaranteeing the execution of the advanced therapeutic manners. Additionally, doping Nd3+ in SrS NPs endows CAS with the second near‐infrared fluorescence to facilitate the in vivo tracing property with good tissue penetration (up to 6 mm). This strategy may play a pioneering role to develop theranostic reagents with improved tumor enrichment capacity and enhanced SDT in hypoxia tumors.
Novel High‐Entropy Air Electrodes Enhancing Electrochemical Performances of Reversible Protonic Ceramic Cells
Authors: Zhang Xiaohan , Tang Chunmei , Yang Yilin , Zheng Fangyuan , Su Qingwen , Xiang Huanxin , Meng Ling , Du Lei , Aoki Yoshitaka , Luo Dongxiang , Wang Ning , Ye Siyu
Published: January 2025

Reversible protonic ceramic cells (R‐PCCs) have been in the spotlight as prominent electrochemical devices for green hydrogen production and utilization. The design of efficient air electrodes is critical for enhancing cell performances, requiring high hydration ability, excellent catalytic activities, and appropriate thermal expansion coefficients (TEC). Herein, novel high‐entropy oxides La(Co0.2Cu0.2Fe0.2Ni0.2Me0.2)O3–δ (Me = Al, Mn, Cr) featuring five cations at B‐site of ABO3 perovskite are presented. La(Co0.2Cu0.2Fe0.2Ni0.2Cr0.2)O3–δ (LCCFN‐Cr) catalyst exhibits the best proton incorporation ability and catalytic activities among three oxides, concluded by analyzing the oxygen vacancy concentration and the chemical bond information. Moreover, the high‐entropy effect at B‐site reduced the TEC of this Co‐contained oxide to a modest extent through large‐ratio substitution of Co by other cations. When applied as an air electrode, the BaZr0.6Ce0.2Y0.1Yb0.1O3–δ electrolyte‐based R‐PCCs yielded a high current density of 2.14 A cm−2 and a peak power density of 0.60 W cm−2, with an extremely low polarization resistance of 0.05 Ω cm2 at 650 °C. These findings not only provide a novel air electrode for R‐PCCs, but also demonstrate a pathway to design effective oxide catalysts for other energy conversion devices by integrating the advantages of Co and high‐entropy effect.
Endeavoring a High Amidoxime Utilization Ratio and Adsorption Capacity for Uranium Extraction From Seawater: A Hydrogen Bonding Reconstruction Strategy
Authors: Yang Guohui , Zhang Yang‐Yang , Zhu Qiu‐Hong , Xia Xue , Pan Ning , Ma Chunyan , Liu Jiale , Liu Yang , Qin Yilin , Zhang Qingdong , Dong Faqin , Li Jun , Nie Xiaoqin
Published: January 2025

Functionalized amidoxime [AO, R−C(NH2)═N(OH)] is widely used for uranium extraction from seawater, but increasing the effective functional sites for high AO utilization in adsorbents remains challenging. This study introduces a hydrogen bond reconstruction strategy to enhance uranium extraction efficiency of AO‐modified polyacrylonitrile (PAN) fibers by blending with polyvinyl alcohol (PVA). The PAN/PVA fibers are synthesized via electrospinning, followed by amidoximation on PAN to prepare PAN‐AO/PVA adsorbents. These materials can extract uranyl ions from the uranyl‐carbonate complex in seawater, achieving an adsorption capacity of 21.0 mg g⁻¹ under simulated seawater conditions with 330 ppb uranium concentration over 24 h. PVA blending increases AO utilization efficiency by 4 times (from 1/291 to 1/69), exceeding most reported values. The adsorbent also shows excellent reusability, retaining over 95% capacity after seven adsorption–desorption cycles. Quantum‐chemical studies based on density functional theory reveal that PVA modulates the hydrogen bonding network by shifting intramolecular bonds in PAN‐AO to intermolecular ones with PVA, increasing permeability and exposing more active N and O sites. Additionally, PVA's hydroxyl groups coordinate with UO₂2⁺, enhancing uranyl adsorption through an enthalpy‐entropy synergy relationship. This strategy offers a practical approach to improving uranium extraction from seawater.
Homogenized Upcycling for Spent LiNi0.5Co0.2Mn0.3O2: Modulating O Vacancies toward Enhanced Structural Stability
Authors: Ge Peng , Wang Bin , Zeng Zihao , Zhu Chao , Lei Hai , Li Jiexiang , Zhou Hanyu , Sun Wei , Yang Yue
Published: January 2025

Fascinated by the high value and low pollution, the direct recycling of spent LiNi0.5Co0.2Mn0.3O2 (S‐NCM) has triggered plenty of exploring activities. Considering different industry sources, they always display various particle sizes and surface traits. Therefore, the simple recovery of chemical defects hardly meets the market demand. Herein, the homogenized strategy, containing physical crushing and chemical recovering, is introduced to regenerate morphology and components of S‐NCM, where the successfully regenerated samples displayed uniform particle size and stable chemical lattice. Assisted by physical crushing, the precursors show a large contacting area with oxygen during morphology reconstruction, accompanied by the effective repairing of the internal lattice. More significantly, the unique manner induces the repairing of oxygen vacancies (OVs) and the lowering of Li/Ni disorder, bringing about enhanced structural stability. Moreover, the lowering of oxygen redox activity and the improvement of oxygen binding energy are further revealed by theoretical calculations. The as‐optimized regenerated samples display a considerable capacity of 139.6 mAh g−1 with a remarkable capacity retention of 94% at 1.0 C. Even at 5.0 C, its capacity retention could be kept at ≈80.8% after 150 loops. Given this, this work is expected to provide effective guidance for different NCM regenerations, meanwhile offering an in‐depth understanding of morphology/lattice reconstruction.
A Modified Polydopamine Nanoparticle Loaded with Melatonin for Synergistic ROS Scavenging and Anti‐Inflammatory Effects in the Treatment of Dry Eye Disease
Authors: Yang Xue , Wang Bowen , Zeng Hao , Liang Lihong , Zhang Runze , Deng Wenrui , Zhao Xuan , Yuan Jin
Published: January 2025

Dry eye disease (DED) is a multifaceted ocular surface disorder that significantly impacts patients’ daily lives and imposes a substantial economic burden on society. Oxidative stress, induced by the overproduction of reactive oxygen species (ROS), is a critical factor perpetuating the inflammatory cycle in DED. Effectively scavenging ROS is essential to impede the progression of DED. In this study, boronophenylalanine‐ containing polydopamine (PDA‐PBA) nanoparticles are developed loaded with melatonin (MT), which are blended with poly(vinyl alcohol) (PVA) to create eye drops PVA/ PDA‐PBA@MT (PPP@MT). In vitro and in vivo studies demonstrate that PPP@MT exhibits dual functionalities in reducing ROS production and downregulating inflammatory pathways, thereby preserving mitochondrial integrity and further inhibiting programmed cell death. Following PPP@MT treatment, tear secretion, corneal structure, and the number of goblet cells are markedly restored in a mouse model of dry eye, indicating the therapeutic efficacy of this agent. Collectively, PPP@MT, characterized by minimal side effects and favorable bioavailability, offers promising therapeutic insights for the management of DED and other ROS‐mediated disorders.
Photosynthesis‐Inspired NIR‐Triggered Fe₃O₄@MoS₂ Core–Shell Nanozyme for Promoting MRSA‐Infected Diabetic Wound Healing
Authors: Xiao Jiamu , An Xuping , Tang Fei , Dai Xu , Zhang Song , Zhu Xiaolong , Shen Jian , Yuan Jiang , Gan Donglin , Wang Mingqian
Published: January 2025

Bacterial infections can lead to severe medical complications, including major medical incidents and even death, posing a significant challenge in clinical trauma repair. Consequently, the development of new, efficient, and non‐resistant antimicrobial agents has become a priority for medical practitioners. In this study, a stepwise hydrothermal reaction strategy is utilized to prepare Fe3O4@MoS2 core–shell nanoparticles (NPs) with photosynthesis‐like activity for the treatment of bacterial infections. The Fe3O4@MoS2 NPs continuously catalyze the production of reactive oxygen species (ROS) from hydrogen peroxide through photosynthesis‐like reactions and convert light energy into heat with a photothermal efficiency of 30.30%. In addition, the photosynthetically generated ROS, combined with the iron‐induced cell death mechanism of the Fe3O4@MoS2 NPs, confer them with exceptional and broad‐spectrum antibacterial properties, achieving antimicrobial activities of up to 98.62% for Staphylococcus aureus, 99.22% for Escherichia coli, and 98.55% for methicillin‐resistant Staphylococcus aureus. The composite exhibits good cell safety and hemocompatibility. Finally, a full‐thickness diabetic wound model validates the significant pro‐healing properties of Fe3O4@MoS2 in chronic diabetic wounds. Overall, the design of photosynthesis‐inspired Fe3O4@MoS2 presents new perspectives for developing efficient photothermal nano‐enzymatic compounds, offering a promising solution to the challenges of antimicrobial drug resistance and antibiotic misuse.
DEyeA: Artificial Muscles for the Restoration of Eye Blinking Following Facial Paralysis
Authors: Konstantinidi Stefania , Koenigsdorff Markus , Martin Pierre‐Jean , Benouhiba Amine , Civet Yoan , Gerlach Gerald , Perriard Yves
Published: January 2025

Facial nerve palsy results in the inability to control facial muscles, including the Orbicularis Oculi, which is the main muscle enabling the blinking action. Blinking is not only important for responding socially to other humans, it is also essential for lubricating the cornea. Without lubrication, loss of vision or eye infections may occur. Current procedures for patients are not always adequate, and there is a real need for more appropriate solutions. This study presents a novel design for a prosthesis that enables the restoration of eye‐blinking abilities in patients with paralysis. The prosthesis consists of an artificial muscle, namely a dielectric elastomer actuator (DEA), used in conjunction with a bistable negative‐rate biasing system (NBS). The prosthesis along with a realistic and anatomically precise eyelid are fabricated and characterized. The specifications in terms of stroke, force and frequency, including opening and closing time of the eyelid, are reached and a natural blinking movement is achieved, with a resulting displacement of the artificial eyelid of 2.5 mm, showing that the use of a DEA with a NBS is a promising approach for the restoration of blinking in the treatment of facial paralysis.
A Paper‐Based Robust Hybrid Photodetector Based on the 2D/0D/0D MoS2/N‐GQD/CsPbBr3 Triple Junction
Authors: Patil Kalyanee , Barve Kanchan , Pisal Akshaya , Ogale Satishchandra , Bhave Tejashree
Published: January 2025

Flexible photodetectors (FPDs) are emerging as essential components for next‐generation wearable optoelectronic devices, bendable imaging sensors, and implantable optoelectronics. However, the development of high‐performance FPDs hinges on the identification of innovative material systems that combine excellent optoelectronic properties, efficient charge transport, and scalable processing techniques. In this study, these challenges by introducing a novel hybrid paper‐based photodetector featuring a 2D MoS₂/N‐doped Graphene Quantum Dot (N‐GQD)/CsPbBr₃ quantum dot triple junction are addressed. This architecture is fabricated entirely through cost‐effective and easily scalable solution‐based methods, emphasizing the practicality of large‐scale production. The incorporation of N‐GQDs as an intermediate layer between MoS₂ nanoflowers and CsPbBr₃ QDs significantly enhances carrier transport and separation, leading to outstanding device performance. The materials and fabricated device are characterized by X‐ray diffraction, Scanning Electron Microscopy, Transmission Electron Microscopy, UV–vis and Photoluminescence spectroscopy, and Ultra Violet photoelectron spectroscopy. The photodetector exhibits a remarkable responsivity of 0.458 A W−1 and a specific detectivity of 3.28 × 10¹¹ Jones, highlighting its potential for high‐sensitivity applications. These results underscore the originality of the triple‐junction design and its significance as a versatile, economical platform for advancing flexible and large‐area photodetectors, paving the way for their deployment in wearable optoelectronics and expanded photo communication technologies.
Microwave Monitoring by Compact Carbon Nanotube Photo‐Thermoelectric Sensors Beyond the Diffraction Limit Toward Ultrabroadband Non‐Destructive Inspections
Authors: Zhang Qi , Li Honghao , Koshimizu Ryo , Takahashi Norika , Kinoshita Yuya , Sano Asumi , Jin Junyu , Okawa Hiroki , Matsuzaki Yuto , Shikichi Daiki , Kawano Yukio , Li Kou
Published: January 2025

Electromagnetic‐wave (EMW) sensing in microwave (MW) frequencies exhibits permeability even to deeper positions of various non‐metallic materials (indispensable for social products) and potentially facilitates non‐destructive inspections. However, conventional MW‐sensor designs generally have faced difficulties in miniaturizations for longer wavelengths and the subsequent diffraction limit. While EMW sensors essentially require pixel miniaturizations for imaging, implementations of typical external antennas concentrating MW‐irradiation into smaller areas than the diffraction limit fatally complicate overall fabrications and operations. Herein, this work demonstrates that carbon nanotube (CNT) film photo‐thermoelectric (PTE) sensors sufficiently handle even MW‐irradiation in compact configurations beyond the diffraction limit by themselves while maintaining inherent operations in shorter‐wavelength millimeter‐wave–infrared bands. The CNT film PTE sensors enhance MW‐detection responses with particular channel dimensions (shorter length and narrower width), demonstrating a signal‐to‐noise ratio of 1497 with a 1‐mm‐square planar structure under 5 GHz irradiation (one‐sixtieth size of the wavelength). In such advantageous behaviors, this work experimentally clarifies that electrically conductive wiring of the CNT film PTE sensor (inherently included within pristine device structures as response signal readout electrodes) plays a key antenna‐like role. Then, the presenting devices demonstrate composition‐identifying non‐destructive testing of complex targets with multiple‐wavelength imaging in ultrabroad MW–near‐infrared bands, while compensating characteristics in respective irradiation regions.
Transforming Agricultural Food Waste Into Bioplastics: Methods, Potential, and Technological Advances
Authors: Asim Zukhruf , Shahzad Hafiz Muhammad Aamir , Ghodake Gajanan , Mahmoud Khaled A. , Almomani Fares , Rasool Kashif
Published: January 2025

The improper disposal of agricultural food waste (AFW) and its associated plastic packaging significantly exacerbates environmental degradation, including pollution, greenhouse gas emissions, and loss of valuable resources, while imposing substantial economic burdens. These pressing challenges have spurred advancements in bioplastics as sustainable and eco‐friendly alternatives to conventional plastics. Here, the potential of AFW, rich in biopolymers such as starch and cellulose, as a renewable feedstock is examined for bioplastics such as polylactic acid, polybutylene succinate, and polyhydroxyalkanoates. It explores the characteristics of these bioplastics, focusing on production techniques such as extraction‐based processes, microbial fermentation, fermentation combined with polymerization, and synthesis from volatile fatty acids. Additionally, the role of AFW pretreatment methods, including physical, chemical, biological, and enzymatic approaches, in enhancing conversion efficiency is analyzed. Here, it is highlighted that recent advancements in bioplastic production have improved efficiency, biodegradability, and scalability, offering a viable substitute for traditional plastics. These findings demonstrate that valorizing AFW not only addresses plastic and food waste challenges but also promotes sustainability and circular economy principles, paving the way for greener industries and reduced ecological impact.
Effect of Wall Slip on the Extrusion Characteristics of 3D Printing of Cementitious Materials
Authors: Wang Yibo , Yan Ming , Yang Kun , Ao Chenyang , Ren Changzai
Published: January 2025

This paper investigates the impact of wall slip on the screw extrusion of cementitious materials. A wall slip extrusion model is developed based on the theory of infinite parallel plates. Then, the extrusion characteristics under different slip conditions of the screw and the cylinder wall are discussed. Finally, the Finite Element Method is used to verify the conclusions drawn from theoretical model analysis. The results show that when −1≤a←1/3 (where a is the ratio of pressure flow to the sum of drag flow and slip flow), slippage on either the screw wall or the cylinder wall can reduce the extrusion flow rate, and the number of flow recirculation planes is one. When −1/3≤a≤1, the number of flow recirculation planes increases to two, and screw wall slip is conducive to expanding the extrusion flow rate. Conversely, cylinder wall slip may reduce the extrusion flow rate. Moreover, the simulation results are consistent with those of the theoretical model, further verifying the rationality of the model.
Conversion–Lithiophilicity Hosts Toward Long‐Term and High‐Energy‐Density Lithium Metal Batteries
Authors: Huang Aoming , Huang Hongjiao , Li Shaoxiong , Pan Xiansong , Wang Ai‐Yin , Chen Han‐Yi , Wang Tao , Li Linlin , Maximov Maxim , Ren Jianwei , Wu Yuping , Peng Shengjie
Published: January 2025

Lithium metal anode emerges as an ideal candidate for the next generation of high‐energy‐density batteries. However, challenges persist in achieving high lithium utilization rates while maintaining the demands of high energy density and extended cycle life. In this work, a novel conversion–lithiophilicity strategy is proposed to regulate the longevity of high‐energy‐density batteries by injecting lithium ion activity. This strategy is validated through carbon nanofiber decorated with Fe3C and Fe2O3 particles. The uniform metallic lithium deposition induced by lithiophilic Fe3C substrates has been verified through lithium deposition/stripping experiments and density functional theory calculations. The electrochemical active Fe2O3 component supplies additional anodic capacity and suppress battery degradation, as demonstrated in lithium‐ion storage research and three electrode system studies. When paired with LiFePO4 cathodes at an N/P ratio of 2, the full battery showcases outstanding cycling stability over 300 cycles at 1C, with an exceptional energy density of 438 Wh kg−1 (calculated based on the cathode material and lithium content). Furthermore, the full battery delivers rapid kinetics of 124 mAh g−1 at 2C. The conversion–lithiophilicity strategy presented offers a promising avenue for the development of high‐energy density and long‐life lithium metal batteries.
Soil test correlation of Olsen‐P for corn and soybean in a subtropical humid region
Authors: Reussi Calvo N. I. , Cortez D. , Crespo C. , Wyngaard N. , Terrazas J. , Paz C. , Trujillo R. , Correndo A. , Garcia F. O.
Published: January 2025

Accurate phosphorus (P) fertilizer recommendations for soybean [Glycine max (L.) Merr.] and corn (Zea mays L.) are crucial for maximizing productivity and economic return while minimizing the environmental impact of fertilizer use. Currently, there are no calibrations for diagnosing P deficiencies in croplands of Bolivia. This study aimed to define and compare the P critical soil test value (CSTV) for corn and soybean using the Olsen method. Twenty fertilization field trials were conducted for corn and 75 for soybean in the Santa Cruz de la Sierra region, including treatments with and without P fertilization. Soil pre‐planting (0–20 cm) organic matter, Olsen P, pH, as well as yield were determined. Relative yield (RY) was estimated as the ratio of grain yield between the control and P‐fertilized treatments. The CSTV was calculated using the arcsine‐logarithm method, with data resampling through bootstrapping. The average yield response to added P was 259 kg ha−1 (+11.0%) for soybean and 545 kg ha−1 (+13.7%) for corn. For soybean, CSTVs were determined as 6.1 and 11.0 mg kg−1 (r = 0.34, p = 0.002) for 90% and 95% of RY, respectively. For corn, the CSTVs were 8.1 and 13.9 mg kg−1 (r = 0.34, p = 0.14) for 90% and 95% of RY, respectively. The confidence intervals suggest no differences between crops. The Olsen‐P is a promising tool for soil fertility recommendations in Bolivia. Yet, the modest goodness of fit obtained suggests the need for further research refining the performance of soil test P diagnosis in the region.
Brownian bridges for contained random walks
Authors: Curtis George , Ramkrishna Doraiswami , Narsimhan Vivek
Published: January 2025

Using linear operator techniques, we demonstrate an efficient method for investigating rare events in stochastic processes. Specifically, we examine contained trajectories, which are continuous random walks that only leave a specified region of phase space after a set period of time . We show that such trajectories can be efficiently generated through the use of a Brownian Bridge, derived via the solution to the Backward Fokker–Planck (BFP) equation. Using linear operator techniques, we place the BFP operator in self‐adjoint form and show that in the asymptotic limit , the set of paths contained in a specified region is equivalent to paths on a modified potential energy landscape that is related to the dominant eigenfunction of the self‐adjoint BFP operator. We demonstrate this idea on several example problems, one of which is the Graetz problem, where one is interested in the survival time of a particle diffusing in tube flow.
The Rapid Rise of Silicosis in Victoria, Australia Associated With Artificial Stone Countertop Industry Work
Authors: Hoy Ryan F. , Tomic Dunya , Gwini StellaMay , Dimitriadis Christina , Abramson Michael , Collie Alex , Barnes Hayley , Glass Deborah C. , Hore‐Lacy Fiona , Kinsman Natasha , Sim Malcolm R. , Walker‐Bone Karen
Published: January 2025

Background

The fabrication and installation of artificial (engineered) stone countertops is a relatively new cause of silicosis. Our aim was to investigate silicosis rates in Victoria, Australia, and the association with stone countertop industry work.

Methods

Workers' compensation claims for silicosis from January 1, 1991 to December 31, 2022 were analyzed across 8‐year time periods. Incidence rates per 100,000 persons were calculated by time period, age, and sex. Additionally, incident silicosis cases were reported to a clinical registry by respiratory physicians from May 1, 2019 to December 31, 2022, and analyzed by referral source and occupational history.

Results

Over 32 years, there were 536 workers' compensation claims for silicosis (98.9% male, median age 40 years). In total, 482 (89.9%) were received between 2015 and 2022, a 27‐fold increase from the previous 8‐year period. The incidence rate for silicosis claims in the adult population increased from 0.12 per 100,000 in 1991–1998 to 2.38 per 100,000 in 2015–2022. In the clinical registry there were 210 incident cases between 2019 and 2022; 97% worked in the countertop industry, 95% with artificial stone. Almost all (89%) cases had been referred following participation in a government screening program for stone countertop industry workers.

Conclusion

There has been a major rise in compensation claims for silicosis in Victoria. Active screening of stone countertop workers led to the diagnosis of almost all registered incident silicosis cases. This underscores the risk to stone countertop workers and highlights the potential for under‐recognition of silicosis without screening at‐risk workers, especially in countries where artificial stone has become popular.
Transition to Adult Care in Turner Syndrome: Research Gaps and Strategies for Achieving Success
Authors: Nahata Leena , Verlinde Franciska , Stochholm Kirstine , Gutmark‐Little Iris
Published: January 2025

Health care transition is a process by which children with chronic medical conditions gradually and purposefully move from pediatric to adult‐centered health care systems. While transition guidelines have been published by multiple national and international organizations, transition processes have not been optimized for many populations, including youth with Turner syndrome (TS). Numerous barriers exist, at both the system and individual/family level. Mitigating transition‐related barriers requires a multi‐faceted approach, including: conducting research to assess TS specific transition interventions and outcomes; developing educational/training initiatives and quality improvement efforts; engaging in advocacy/policy change; and implementing evidence‐based strategies to optimize transition. The goals of this manuscript are to outline key research gaps that need to be addressed regarding health care transition in TS and to suggest strategies to optimize transition outcomes. Given the importance of a multi‐disciplinary and patient‐centered approach, we specifically outline the roles of pediatric health care teams (including navigators), adult health care teams, patients, caregivers, and institutional resources.
Efficacy of Using Photobiomodulation Therapy in Allergic Rhinitis: A Placebo‐Controlled Randomized Clinical Trial
Authors: Oliveira Patrícia Costa , Correia Luísa Oliveira , Lopes Natália Medeiros Dias , Molossi Julia , Fornazieri Marco Aurélio
Published: January 2025

Background

Recent studies have extensively explored new non‐invasive and side‐effect‐free therapeutic strategies for the treatment of allergic rhinitis (AR). Photobiomodulation therapy (PBMT) utilizes photons from the red to infrared spectrum to modulate biological processes, exhibiting anti‐inflammatory and regenerative properties. The objective of our study was to evaluate the efficacy of PBMT in patients with AR.

Methods

This study was a randomized, placebo‐controlled, double‐blind clinical trial involving 62 patients with AR. Participants underwent PBMT twice weekly, totaling eight sessions over the course of 1 month. The control group consisted of 29 patients who received treatment with a non‐light‐emitting device, while 33 patients in the laser therapy group received a protocol of 6 J of red and infrared light administered intranasally, along with 1 J of infrared light applied externally to the nose. Objective, psychophysical, and subjective assessments of nasal obstruction and olfactory function were conducted both before and after the treatment.

Results

PBMT contributed to significant improvements in various nasal and respiratory parameters. The peak nasal inspiratory flow demonstrated significant improvement (p < 0.001), and the Nasal Obstruction Symptom Evaluation scale indicated notable enhancement in nasal obstruction (p = 0.048). Additionally, the Rhinitis Control Assessment Test reflected significant symptom improvement over the past week (p = 0.035). However, the University of Pennsylvania Smell Identification Test showed no significant change in olfactory function (p = 0.251).

Conclusion

Our data suggest that PBMT may serve as a promising therapeutic option for individuals with AR, providing an alternative for those who are unable to tolerate conventional medications. Furthermore, it demonstrates efficacy and safety as a viable treatment alternative.
Persistent Eosinophilic Inflammation Is Not a Feature of Type 2 CRS Patients Failing Anti‐IL‐5R Therapy and Requiring Class Switching to Anti‐IL‐4/13
Authors: Sacks Peta‐Lee , Meerwein Christian M , Earls Peter , Thiel Cedric , Choy Christine , Campbell Raewyn G , Sacks Raymond , Kalish Larry , Harvey Richard J
Published: January 2025

Background

Type 2 inflammation dominates eosinophilic chronic rhinosinusitis (eCRS) and adult onset asthma. IL‐4, ‐5, and ‐13 are prominent disease mediators. Disease control can be achieved with biologic therapies. However, despite some patients entering remission, others experience poor control.

Aim

We aimed to describe eCRS patients treated with anti‐IL‐5R antibody (benralizumab) and assess characteristics between responders and those requiring class switching to anti‐IL‐4/13R (dupilumab).

Method

A retrospective cohort study was performed on consecutive adult patients with eCRS and asthma who had commenced benralizumab.  Disease control was defined as controlled or poorly controlled (EPOS2020 partly control/uncontrolled). Poorly controlled patients were switched to dupilumab.  Baseline and post‐IL‐5R characteristics including age, sex, 22‐item Sinonasal Outcome Test (SNOT‐22), Asthma Control Questionnaire (ACQ) score, and serum/tissue eosinophilia were assessed. Disease control post‐class switching was reassessed. Factors predicting poorly controlled disease on anti‐IL‐5R therapy were sought.

Results

Fifty patients were assessed (51.44 ± 12.73 years, 56% female). Poorly controlled disease on anti‐IL‐5R requiring class switch to dupilumab was seen in 42%. Poorly controlled patients were younger (46.14 ± 10.76 vs. 55.28 ± 12.83 years, p = 0.01) with higher baseline SNOT‐22 (61.42 ± 19.19 vs. 42.32 ± 21.55, p < 0.01). Baseline ACQ scores and eosinophil count (0.78 ± 0.49 vs. 0.62 ± 0.34 × 109cells/L, p = 0.23) and were similar between groups. In the poorly controlled patients on anti‐IL‐5R therapy, eosinophilia had reduced in both serum (0.78 ± 0.5 vs. 0.02 ± 0.1 × 109cells/L, p < 0.01) and tissue (>100 cells/HPF: 100% vs. 29%, p = 0.01). Class switching resulted in disease control for 65%.

Conclusion

Neither eosinophilia nor its reduction predicted a non‐responder group to anti‐IL‐5R therapy. While the eosinophil population may be a good marker for the CRS phenotype seen in nasal polyps, it is unlikely to be the cell population driving the disease process.