bluuebunny/crossref_metadata_2025 huggingface dataset:
SMART TRAVEL: YOUR ULTIMATE ITINERARY COMPANION
Authors: Mr Dharmendra Kumar Roy  , P. Tejaswini  , P. Umesh Chandra  , T. Jyothi Latha  , M. Deeksha
Published: October 2024

Travel planning can be a complex and time-consuming task, often leaving travelers
feeling overwhelmed by the abundance of choices and information available. In response to these
challenges, we present a Travel Itinerary Planner designed to streamline the planning process and
provide personalized recommendations tailored to individual preferences. Drawing upon recent
advancements in artificial intelligence and data analytics, our platform employs machine learning
algorithms to analyze user profiles and generate customized itineraries encompassing
accommodations, transportation options, and activities. Through flexibility, integration with
external services, and continuous optimization, our solution aims to enhance the travel experience
by offering convenience, authenticity, and efficiency. We can enhance the travel planning
experience by incorporating a map feature into our platform. This feature can display the itinerary
visually, showcasing the planned destinations, accommodations, and points of interest. Users can
interact with the map to get a better understanding of their trip and explore nearby attractions.
Integrating a map feature adds another dimension to our Travel Itinerary Planner, providing users
with a comprehensive and intuitive tool to plan their journeys effectively.
REMOTE SENSING DATA ANALYSIS OF DEBRIS FLOWS IN DRAINAGE BASINS IN BULGARIA
Authors:   Sofia University, Faculty of Geology and Geography, Department of Climatology, Hydrology and Geomorphology, Sofia, Bulgaria, Tamburadzhiev Ilia
Published: October 2024

The present study is focused on remote sensing data analysis of the factors for formation and development of debris flows in various mountain drainage basins in Bulgaria. The extent of susceptibility to the formation and development of debris flows in the range of selected mountain key sections of the drainage basins was investigated and a risk assessment was carried out. The relevance of the present study is related to the frequency of adverse hydro-climatic phenomena of natural and anthropogenic origin in the last decade in different parts of Bulgaria—Asparuhovo (2014), Karlovo (2022), Berkovitsa (2023), Tsarevo (2023), etc. Similar events cause lasting damage to infrastructure, economy, and public life, and sometimes lead to human casualties. The role of geological-geomorphological factors, water runoff, and land cover was studied. A morphometric analysis of the relief was carried out in order to obtain specific values of the morphometric characteristics of the drainage basins and the channel networks. To achieve the goal of the study, an analysis and synthesis of scientific literature on risk, hydro-climatic, and geomorphological phenomena in the studied drainage basins was carried out. GIS methods were used to calculate morphometric indicators/parameters (such as area, perimeter, length and width of the drainage basin, hypsometric integral, Melton ratio, total length of the river network (km), total number of tributaries (N), circularity ratio, bifurcation ratio, density of the river network (km/km2), frequency of streams (count/km2), etc.) and for calculation of the Normalized Difference Vegetation Index (NDVI). Hydrological modeling was carried out in order to extract the channel networks. The channel networks were classified by stream ordering. GIS analysis is done on the basis of SRTM Digital Elevation Model (DEM), Landsat multispectral satellite images, topographic maps, geological map, etc. Mapping and risk assessment of debris flows has been carried out which is a first step in disaster risk reduction and management.
IMPORTANCE OF SPECIES DISTRIBUTION MODELLING IN NATURE CONSERVATION: CASE STUDY OF GLACIAL RELICT THREE-TOED WOODPECKER „PICOIDES TRIDACTYLUS“
Authors:   Geographical Institute “Jovan Cvijić”, SASA, Belgrade, Serbia, Popović Teodora , Ćurčić Nina B. ,   Geographical Institute “Jovan Cvijić”, SASA, Belgrade, Serbia, Đurđić Snežana ,   University of Belgrade, Faculty of Geography, Department of Physical Geography, Belgrade, Stanojević Gorica ,   Geographical Institute “Jovan Cvijić”, SASA, Belgrade, Serbia, Raković Marko ,   University of Belgrade, Institute for Multidisciplinary Research, Department of Biology and Inland Waters Protection, Belgrade, Serbia
Published: October 2024

Identifying geographic areas with habitats suitable for the presence of priority species is of essential importance in conservation planning. A useful tool to identify these areas is a species distribution modelling (SDM), which is a method that defines statistical relationship between species records and environmental variables in the localities where the species is present. To test the possibility of applying this method in conservation planning, this study focused on the Three-toed Woodpecker Picoides tridactylus (Linnaeus, 1758) (Piciformes: Picidae) because it is a glacial relict on the Balkan Peninsula that is distributed only in montane coniferous and mixed forests with significant amounts of dead wood. As a habitat specialist, it is vulnerable to environmental changes, making it a suitable indicator species for forests with natural properties. These forests are threatened by modern forestry which removes the dead wood necessary for the Three-toed Woodpecker’s survival, and land-use changes, such as urbanisation of mountains. Moreover, as a glacial relict, this species is threatened by global warming which represents a challenge for its future survival. The results show that highly and moderately suitable habitats (habitat categories essential for specialist species) have the smallest areas in total suitability of the Balkan Peninsula. Along with their limited presence, what makes conservation of these habitats more difficult is the fact that their distribution is mostly fragmented. For these reasons, ensuring their preservation and connectivity of given habitats should become a conservation priority. Geographic areas deemed important by SDM, such as the Dinarides mountain range in our case study, can be used as a focus for further research and field trips, thereby saving both time and resources. Another advantage of this method is that it can be used to assess the impacts of climate change on species distribution by creating future projections using global climate models. Distribution models can also be used to evaluate the effectiveness of protected areas. These examples demonstrate that using SDM can produce the knowledge necessary for conservation, which makes this method useful in nature conservation and planning.
THE DEVELOPMENT OF ENVIRONMENTAL THOUGHT IN SLOVENIA
Authors:   Research Centre of the Slovenian Academy of Sciences and Arts, Anton Melik Geographical Institute, Ljubljana, Slovenia, Polajnar Horvat Katarina , Smrekar Aleš ,   Research Centre of the Slovenian Academy of Sciences and Arts, Anton Melik Geographical Institute, Ljubljana, Slovenia
Published: October 2024

The development of environmental thought in Slovenia has evolved significantly over the past century, shaped by key milestones and socio-political shifts. This paper examines this progression, from early nature conservation efforts to contemporary environmental policies, within global and European contexts. Within the Kingdom of Serbs, Croats, and Slovenes, the initial phase began in 1920 with the nature protection program by the Museum Society, which was based in Ljubljana, a pioneering document on an international level. The 1960s were critical, with growing public awareness in the Western world influencing Slovenian environmental thought within the context of socialist Yugoslavia, spurred by works like Rachel Carson’s Silent Spring (1962) and Garrett Hardin’s The Tragedy of the Commons (1968). In the early 1970s, environmental concerns gained prominence due to deteriorating conditions and global movements. During the socialist period, environmental issues were often subordinated to rapid industrialization. However, the 1980s saw increased environmental activism in Slovenia, addressing pollution from industrial activities such as the Krupa River contamination and waste disposal of the uranium mine at Žirovski vrh. This era also saw the establishment of the Greens of Slovenia, which gained 8.8% of the vote in the 1990 elections, marking a strong green political presence. A significant shift occurred following Slovenia’s independence from Yugoslavia in 1991, with the adoption of the Environmental Protection Act in 1993, incorporating principles of sustainability and preventive action. Slovenia’s accession to the European Union in 2004 further solidified its environmental framework, aligning national policies with stringent EU standards and promoting sustainable development and public participation in governance. The 2008 economic crisis posed additional challenges, temporarily sidelining environmental issues as economic concerns took precedence. However, it also underscored the need for sustainable economic models, integrating environmental considerations into recovery efforts. The decade from 2010 to 2020 saw further integration of environmental policies, emphasizing renewable energy and sustainable practices. Public engagement and environmental education became more prominent. The European Green Deal, launched in 2019, plays a crucial role in Slovenia’s environmental strategy, aiming to make Europe climate-neutral by 2050. Slovenia has embraced this initiative, focusing on green technologies and sustainable practices, and integrating these principles into national policies.
REGIONAL ASPECTS OF THE DEMOGRAPHIC CRISIS IN BULGARIA
Authors:   National institute of Geophysics, Geodesy, and Geography, Bulgarian Academy of Sciences, Sofia, Bulgaria, Kazakov Boris
Published: October 2024

The paper analyses the current demographic situation in Bulgaria based on the results of the latest population census conducted in the country (September, 2021), provided by the National Statistical Institute (NSI). All major demographic indicators have been analysed (population number, population density, population dynamics, urban and rural population, as well as some of the basic socio-demographic structures of the population) at national and regional (NUTS 3) level. The focus of the analysis falls on the regional disparities—highest and lowest values of the demographic indicators, and most importantly—on the major factors that contribute to the observed differences. The analysis shows that the loss of population in the decade between the two latest population censuses (2011 and 2021) is the highest in the recorded demographic history of the country in both absolute and relative numbers, while the age structure of the population is at its worst, which are the main features of the demographic crisis in Bulgaria. All demographic aspects, however, exhibit significant disparities at regional level, while at lower regional level (LAU 1) opposite extremes are even observed, resulting in the formation of several “islands of demographic prosperity” across the country, located within a vast territory exhibiting an overall demographic collapse, where some areas can be referred to as a “demographic desert”. Last, but not least, the results of a demographic projection of the population as of 2050 have been provided.
EXPLAINING VOTERS MOBILIZATION IN LOCAL ELECTIONS IN ETHNICALLY DIVIDED SOCIETY—THE CASE OF NORTH MACEDONIA
Authors:   Wrocław University of Environmental and Life Sciences, Faculty of Spatial Management and Landscape Architecture, Institute of Spatial Management, Wrocław, Poland, Swianiewicz Paweł ,   National Institute for Local Government, Lodz, Poland, Kreci Veli ,   South-East European University in Tetovo, Faculty of Contemporary Social Sciences, Tetovo, North Macedonia,   Max van der Stoel Institute, Tetovo, North Macedonia
Published: October 2024

North Macedonia is a country in which the variation in local electoral participation belongs to the highest in Europe (coefficient of variance 0.148 in 2013 and 0.200 in 2017, even 0.214 in 2021). This paper tries to explain this variation through series of regression models including several independent variables. In additional to typical factors taken into account in such analysis in earlier studies (population size of local community, competitiveness of elections, and social status of residents) the country specific variable—ethnic composition of population in individual municipalities is taken into account. In individual models dependent variables are: 1) turn-out in local elections, 2) difference between turn-out in national and local elections, and 3) competitiveness of local elections measured by the difference between votes for two major candidates in mayoral elections. In most of North Macedonian municipalities there is a clear domination of one ethnic group (usually either Macedonian or Albanian), but there are also communities in which there is an almost equilibrium with two or more ethnic groups of comparable size. The paper investigates how ethnic composition modifies the model based on “conventional” explanatory variables. Those “ethnically balanced” municipalities are in a special focus of the paper. Empirically the paper investigates turn-out in 2013 and 2021 elections. The reason of including 2013 results in the analyses is related to particular time of voting, very close to national holidays in most of West European countries, which has enabled casting vote by numerous “non-resident citizens” and boosted overall turn-out. Since participation of „non-resident population“ may change the ethnic balance in some of North Macedonian municipalities, taking into account timing of elections seems to be very important. Overall results suggest that the balanced ethnic structure may have some importance for voters’ mobilization, however its role is less important than it might be expected. The most important explanatory variables are population size of municipality (similar to factors found in other countries) as well as proportion of ethnic Macedonians (ethnic Macedonians seems to be more attached to state institutions, and their civic activeness is higher than in case of other groups).
Costus Afer Stem Juice Extract Enhances Wound Healing Process Through the Modulation of the Expression of TGF-Β1 at Wound Site
Authors: Udoh Kudighe P
Published: October 2024

Recent studies have explored the potential of Costus afer stem juice in supporting the process of tissue repair and regeneration. This study sought to expand on those discoveries by assessing the expression of transforming growth factor beta 1 (TGF-β1) in wounds treated with C. afer stem juice extracts. Ninety-six adult Wistar rats, divided into four groups, were used to study the wound healing process over 24, 72 and 120 hours, as well as at complete healing. The rats were wounded on their dorsum and treated on the first day according to their group: Group A received no treatment, Group B was treated with honey gel, Group C with heat-dried C. afer stem juice extract and Group D with freeze-dried C. afer stem juice extract. The result of the study showed that the expression of TGF-β1 was initially highest in group D which gradually declined to the lowest at 120 hours and peaked again in the healed tissues. Group C wounds showed the lowest level of expression of TGF-β1 at 24 hours, which increased at 72 hours and gradually fell to be at the same level as group B and group A wounds in the healed tissues. The deposition of granulation tissues and extracellular matrix fibres in group D followed the same pattern as expression of TGF-β1. In conclusion, the extract of C. afer stem juice enhanced the healing process through the modulation of TGF-β1 expression.
DEMOKRAT PARTİ DÖNEMİ’NDE İMAR KANUNUNDA DEĞİŞİKLİKLER VE ANKARA’DA MEYDANA GELEN SEL FELAKETLERİ
Authors: Baysal Uğur
Published: October 2024

Türk Siyasi hayatının hassas bir döneminde iktidara gelen Demokrat Parti, on yıllık döneminde siyasal ve sosyal çalkantıların, dış politik gelişmelerin ve günümüze kadar sürecek darbe tartışmalarının bitmeyeceği gözükmektedir. İç politikanın gölgede kaldığı dış politikasının ise gündemin belirleyicisidir. Bunda, II. Dünya Savaşı sonrası yeni bir dünyanın tesis edilmesinin ve gelişen güç blokları karşısında Türkiye’yi konumlandırma çalışmalarının payı vardır.
Ankara’nın şehir merkezinde ve tarımsal alanlarında mal ve can kayıplarına yol açan doğal afet kaynaklı zararlar devlet yetkililerinin başlıca uğraş alanı olmuştur. Başkentin sel baskınlarına sıklıkla maruz kalması, burada yaşayan insanların hayatlarını olumsuz yönde etkilemiştir. Aşırı yağışlarla taşan dere yatakları setleri yıkarak, yerleşim ve tarım alanlarında büyük tahribatlara yol açmıştır. Sel felaketinin yaşandığı afet bölgelerine siyasiler tarafından ziyaretler yapılmış ve yaşanılan acılar paylaşılmaya çalışılmıştır.
İmar Kanunu’nda yapılan sık sık değişiklikler seçimlere yönelik politikaların tezahürüdür. Çoğunlukla yerel ve genel seçimler öncesi kısmi ve kapsamlı gecekondu aflarını getiren Demokrat Parti, şehirlerdeki hızlı değişim ve plansız yapılaşmaya karşı yürüttüğü mücadele zaafiyete uğramıştır. Başta Ankara ve İstanbul olmak üzere büyük şehirlerde doğal afetlerin yaşanmasında uyguladığı popülist politikaların kurbanı olmuştur. Bu dönemde imar uygulamaları ve alınan tedbirler daha çok doğal afetler yaşandıktan sonra gerçekleşmiştir. Dolayısıyla bu çalışma, Ankara’nın yereldeki en önemli sorunu olan sel felaketleri incelemeye değerdir.
KARAKOL CEMİYETİ ÜYESİ: ŞEYH ATÂ EFENDİ(1883-1936)
Authors: İnce Merve Kübra
Published: October 2024

Millî Mücadele yıllarında Özbekler Tekkesi’nin postnişinde bulunan Şeyh Atâ Efendi(1883-1936) Karakol Cemiyetine mensup olması ile Millî Mücadele’de önemli rol oynamıştır. Şeyh Atâ Efendi başında bulunduğu Özbekler Tekkesini Karakolcuların çeşitli faaliyetlerinde kullanmalarına müsaade etmiştir. Özbekler Tekkesi Karakol Cemiyeti’nin İstanbul-Anadolu arasındaki faaliyetlerini gerçekleştirirken kullandığı gizli merkez konumuna gelmiştir. Karakolcular için bir misafirhane, hastane, cephane, postane teşkilatı olarak hizmet vermiştir. İstanbul’dan Anadolu’ya geçmek isteyen Millî Mücadele yanlılarına ev sahipliği yapmıştır. İstanbul’dan Anadolu’ya geçiş için oluşturulan kara yolu “Menzil Hattı’nın” başlangıç noktası Özbekler Tekkesi’dir. Şeyh Atâ ve Karakolcuların birlikte yaptıkları kaçış planları doğrultusunda güvenli ortam oluşturulduğunda Tekke aracılığıyla Anadolu’ya silah, cephane ve eleman kaçırılmıştır. İsmet İnönü, Saffet Arıkan, Halide Edip Adıvar, Mehmet Akif Ersoy ve dönemin önde gelen asker, bürokrat ve aydınları Ankara’ya Şeyh Atâ aracılığıyla geçmişlerdir. Bu çalışmada Karakol Cemiyeti mensuplarından Özbekler Tekkesi şeyhi Atâ Efendi’nin Millî Mücadeledeki rolü değerlendirilecektir. Millî Mücadele kahramanlarından biri olan ancak adı unutulan Şeyh Atâ Efendi bu çalışma ile tekrar hatırlatılacaktır.
Mengatasi Hambatan Komunikasi Antar Budaya
Authors: Putri Khinantie Winarto , Widiyanarti Tantry , Putri Khinandha Aulia Winarto , Naila Siti Sarah , Mukhlisin Akhmad Syirojul , Purwanto Eko , Rahmah Ade
Published: October 2024

Komunikasi antar budaya merupakan interaksi antara individu dari latar belakang budaya yang berbeda, yang menuntut pemahaman mendalam terhadap konteks budaya untuk mencapai komunikasi yang efektif. Hal ini meliputi dimensi kognitif, perilaku, dan afektif yang penting dalam membangun interaksi yang tepat dan mengurangi kesalahpahaman. Proses ini bersifat interdisipliner, menggabungkan linguistik, psikologi, dan sosiologi, serta menekankan bahwa budaya bersifat dinamis. Metode yang digunakan adalah studi pustaka (library research) yaitu metode dengan pengumpulan data dengan cara memahami dan mempelajari teori-teori dari berbagai literatur yang berhubungan dengan penelitian tersebut. teknik pengumpulan data yang dilakukan adalah internet searching. Hasil penelitian menemukan bahwa pelatihan komunikasi antar budaya sangat penting bagi individu, untuk memahami perspektif yang beragam dan membangun rasa saling menghormati di dunia global. Hambatan dalam komunikasi sering muncul akibat perbedaan bahasa dan norma sosial, sehingga pemahaman terhadap norma-norma ini menjadi krusial. Kepercayaan juga berperan penting dalam membangun hubungan harmonis antar budaya, di mana kesadaran akan perbedaan dapat mendorong kolaborasi yang lebih baik. Strategi manajemen yang efektif diperlukan untuk menjembatani kesenjangan budaya dalam organisasi, termasuk membangun jalur komunikasi yang jelas dan meningkatkan kesadaran lintas budaya.
Strategi Komunikasi Lintas Budaya
Authors: Mumtaz Nazwalia Fairuz , Widiyanarti Tantry , Pratiwi Erida Eka , Deswita Dhelza , Purwanto Eko , Rahmah Ade
Published: October 2024

Strategi komunikasi antarbudaya menjadi semakin penting dalam konteks globalisasi yang semakin meningkat. Dalam interaksi antarbudaya, terdapat risiko kesalahpahaman yang dapat menghambat komunikasi efektif. Ulasan ini membahas pentingnya strategi komunikasi antarbudaya untuk mengatasi perbedaan nilai, norma, dan praktik budaya yang ada. Komunikasi antarbudaya melibatkan pertukaran informasi antara individu atau kelompok dari latar belakang budaya berbeda, di mana bahasa, simbol, dan konteks sosial memainkan peran penting. Strategi komunikasi yang efektif harus dirancang untuk mengatasi hambatan-hambatan ini dan menciptakan pemahaman yang lebih baik. Artikel ini juga menyoroti dua aspek utama strategi komunikasi: pendekatan makro dan mikro. Pendekatan makro melibatkan penggunaan media massa untuk menjangkau khalayak yang lebih luas, sedangkan pendekatan mikro lebih fokus pada interaksi langsung antar individu. Dengan memahami dan menerapkan strategi komunikasi antarbudaya yang tepat, organisasi dapat meningkatkan hubungan antarbudaya dan mencapai tujuan komunikasi yang diinginkan.
Overcoming Barriers: Diagnosis of High-Grade Melanoma: Perspective from a Clinical Case
Authors:   Hospital General de Zona 1, Villa De Álvarez, Colima Department of Internal Medicine. Orcid: 0009-0009-2577-8656, Ramírez Fátima G. Morán , Rios Eder F. ,   Hospital General de Zona 1, Villa De Álvarez, Colima Department of Internal Medicine. Orcid: 0000-0002-4660-7372, Baez Gerardo De Jesús Rodríguez ,   Centro Médico Nacional de Occidente, Guadalajara, Jalisco. Orcid: 0009-0007-4316-81
Published: October 2024

We present the case of a 30-year-old male patient with loss of visual acuity in the left eye. The imaging study detected a lesion of high suspicion of tumor in the left eye. Enucleation of the left eye was performed, confirming the diagnosis of choroidal melanoma by histopathological study. Subsequently, the disease progressed with neoplastic activity in the lungs, liver, lymph nodes and central nervous system. A case description is provided along with a bibliographic review, focusing on the approach and prognostic factors in patients with metastatic disease.
Article RETRACTED due to manipulation by the authors Psychological resilience and performance under pressure: a study of elite badminton players - a systematic review
Authors: Dwihandaka Riky , Ihsan Fadli , Nugroho Sigit , Kozina Zhanneta , Arzhan Hidayat Rezha
Published: October 2024

Psychological resilience is a critical factor influencing athlete performance in many sports, including badminton. This study aims to systematically review the existing literature to understand the relationship between psychological resilience and elite badminton athlete performance. The research background details the importance of psychological factors in the context of sport, particularly under competitive pressure. Focusing on elite badminton players, the study aimed to identify consistency and variation in previous research findings and detail the practical implications for athlete training and coaching. Research materials and methods included a systematic design with explicit inclusion and exclusion criteria. A thorough literature search was conducted to identify relevant studies that met the inclusion criteria. A careful study selection process was completed, and data were extracted for systematic analysis. Data analysis methods used included synthesizing findings from multiple studies, potentially using meta-analysis where appropriate. The results present the main findings regarding the relationship between psychological resilience and the performance of elite badminton athletes. The analysis of findings from multiple studies highlights the consistency in this relationship while acknowledging the variation that may occur due to differences in competitive context and athlete characteristics. The practical implications of these findings are explained in the context of training and coaching badminton athletes to enhance their psychological resilience under competitive pressure.The research conclusions highlight the vital contribution of this study to understanding psychological factors in badminton. This research provides a foundation for developing more effective training strategies and coaching of athletes that can enhance their psychological resilience, thereby improving their performance at the elite level. As such, this study provides scientific insights and practical guidance for the potential development of elite badminton athletes under competitive pressure.
The Importance of Klebsiella pneumoniae as a Pathogen and the Increasing Prevalence of Antibiotic-Resistant Strains and Molecular Characteristics
Authors: Mohammed Waleed , Fatimah Abdulazeez Awad  , Thana I. Mustafa
Published: October 2024

Klebsiella pneumoniae is a significant pathogen causing various infections, and antibiotic-resistant strains of K.pneumoniae are becoming more prevalent. Molecular studies reveal the genetic mechanisms underlying antibiotic resistance, such as resistance genes on plasmids that can easily spread between bacteria. Knowledge of the molecular characteristics of antibiotic-resistant strains is crucial to develop effective strategies against their spread. The bacteria can easy colonizes the human gut and  can also cause a range of infections, including pneumonia, urinary tract infections, and bloodstream infections.
The emergence of antibiotic-resistant strains of K.pneumoniae has become a major public health concern, as these strains are associated with increased morbidity and mortality rates, longer hospital stays, and higher healthcare costs. Antibiotic resistance in K.pneumoniae involves several mechanisms, including beta-lactamase production, changes in outer membrane porins, and the uptake of resistance genes via horizontal gene transfer. 
The genetics and genomics of K.pneumoniae are also of significant interest, as they provide insights into the diversity of strains and their pathogenic potential. Genome sequencing has revealed the existence of distinct lineages of K. pneumoniae, each with unique virulence factors and antimicrobial resistance profiles. 
To summarize, K.pneumoniae is a critical pathogen that poses a substantial global public health threat. The rising prevalence of antibiotic-resistant strains underscores the pressing need for innovative approaches to prevent and treat K.pneumoniae infections. Comprehensive knowledge of the molecular mechanisms of virulence, pathogenicity, and antibiotic resistance, as well as the genetic diversity of K. pneumoniae, will be essential in developing effective strategies to combat this pathogen.
The impact of COVID-19 of blood donations and blood components usage in Ceará, Brazil
Authors: Martins Feitosa Deymisson Damitene , Mesquita Felipe Pantoja , Cândido Santos Franklin José , De Barros Carlos Luciana Maria , Ferreira Gomes Vânia Barreto Aguiar , Cavalcante Ribeiro Jannison Karly , ALEXANDRE DE AQUINO PEDRO EEVERSON
Published: October 2024

Abstract
With increase cases of Coronavirus disease in Brazil and the virus propagation around the world, several health sectors were negatively affected, including hemotherapy services and generating a decrease in blood donation. In this study, we gathered information about total blood donations and usage during COVID-19 pandemic in the state of Ceará, located in the northeast side of Brazil. More specifically data from donations between April 2020 and September 2021 and compared with data gathered from donations of pre-pandemic period. During the period, the state of Ceará received 181.362 candidates for blood donation. Of these, 80.16% were eligible for donation and 19.84% unfit. The number of candidates decreased by 16.72% in 2020 and 5.10% in 2021 in comparison to the same periods in 2018. The main causes of inability for candidates during the pandemic period were low hematocrit/hemoglobin, occasional sexual intercourse in the last 12 months and suspicion or confirmation of COVID in the last 10 days. However, the increasing number of critically ill hospitalized COVID patients increased the blood supply, as transfusions increased by 1.03% in 2020 and 7.96% in 2021, showing a higher demand in RBC, platelets, FFP and CRYO. The pandemic had a significant impact on national blood stocks, causing a change in donation behavior and causing a concern to maintain an adequate blood supply during this crisis. Despite the situation, the stock of blood components in HEMOCE met the Ceará blood demand in the hospitals.
Prediction of live weight from body measurements using stepwise regresion models in Karacabey Merino lambs
Authors: Kabasakal Adem
Published: October 2024

Objective: The aim of this study is to determine regression models that can be used to estimate live weight from body measurements in Karacabey Merino lambs of different ages(6th, 8th, and 12th months)..
Material-Method: The animal material for the study consisted of 200 Karacabey merino lambs. Some body measurements were taken from all lambs and live weights were also weighed. For live weight prediction equations with multiple linear regression analysis using some measurements according to age groups, stepwise multiple regression procedure was used in SAS (1999). DUNCAN test, one of the tests for multiple comparisons, was used to show the differences between groups.
Result: The least squares means for body length (BL), withers height (HW), back height (BH), rump height (RH), breast depth (CD), breast width (CW), rump width (RW), and live weight (LW) were 71.28 cm, 69.91 cm, 70.50 cm, 71.57 cm, 30.05 cm, 87.25 cm, 21.50 cm, 23.32 cm, and 51.05 kg, respectively. It is noteworthy that the live weight estimation models for three different age groups using stepwise regression analysis(second, third, and fourth models) can be recommended for the 6th (R2:0.82), 8th (R2:0.71), and 12th (R2:0.79) months of life. The variables that can be used in the equations to estimate body weight for this breed, at these ages are HW, CW, RW, CG, CD, and BL.
Conclusion: Finally, it has been demonstrated that the live weights of Karacabey merino lambs can be estimated with high accuracy using the stepwise regression method based on body measurements.
Original articleAbdominal pelvic radiotherapy prolongs surgical time of retrograde endoscopic treatment of upper urinary tract stones
Authors: Canos-Nebot Àngela , Caballero Romeu Juan Pablo , Caballero Pablo , De la Encarnación Castellano Cristina , Mendiola López Alberto , Galiano Baena Juan Francisco , Montoya Lirola María Dolores , Galán Llopis Juan Antonio
Published: October 2024

Objective: the main objective is to assess whether urolithiasis diagnosed in patients with previous APRT need more endoscopic procedures to reach stone-free status and if these procedures are longer. The secondary objective is to find out if these patients have more complications resulting from endourologic procedures.
Design and methodology:  we designed a case-control unicentric study including patients with upper urinary tract lithiasis treated with retrograde ureterorenoscopy (URS) between 2006 and 2022. Case patients have previous history of APRT, while controls are patients without this history. We collected epidemiological, lithiasis and treatment related information in both groups.
Results: we identified 18 upper urinary tract stones in cases that underwent endoscopic retrograde treatment. We linked these urinary stones with 18 urolithiasis diagnosed in control patients. The average age in patients and the diameter of the stones diagnosed were very similar in both groups, as well as the stones’ location. Longer surgical time was found for lithiasis treatment in case patients (129.6 versus 80.2 minutes in controls, p = 0.025). No significant differences were found regarding the rest of variables.
Limitations: this is a retrospective and observational study, and the sample size is small, so we need to expand to a multicentric study.
Originality and value: to our best knowledge this is the first study to provide data on how APRT may affect the effectiveness of endourological treatment of urolithiasis.
Conclusion: endourological procedures for treatment of upper urinary tract stones in patients with previous APRT are longer than in patients without this background.
NUEVO REGISTRO DE Misumena vatia (Clerck, 1757) (ARANEAE: THOMISIDAE) EN CERRO PUNTA – CHIRIQUÍ, PANAMÁ
Authors: Collantes Rubén , Garrido Anette , Díaz Darwin
Published: October 2024

Las arañas cangrejo (Araneae: Thomisidae), son depredadores naturales de insectos en áreas próximas a cultivos, siendo los thrips (Thysanoptera: Thripidae), plagas de importancia para varias hortalizas. Entre septiembre y noviembre de 2022, se observó tanto en parcelas de cebolla como en flores de margaritas en Cerro Punta, Tierras Altas – Chiriquí, Panamá (8°51’13” N 82°34’16” O, 1949 msnm), la presencia de arañas cangrejo de color amarillo y blanco; por lo que el objetivo fue identificar dicha especie. Se colectó un espécimen, el cual fue preservado en etanol al 70% para ser revisado en el laboratorio de la Estación Experimental de Cerro Punta – Instituto de Innovación Agropecuaria de Panamá y en el Museo de Invertebrados G. B. Fairchild – Universidad de Panamá, consultándose además literatura especializada. Los caracteres morfológicos observados, principalmente el epigíneo, se aproximan a la especie Misumena vatia (Clerck, 1757), siendo este, hasta donde se conoce, un nuevo registro para Panamá.
CANNIBALISM IN WHIP SPIDERS OF THE GENUS PHRYNUS SP. (ARACHNIDA: AMBLYPYGI) IN PANAMA
Authors: Fuentes Rogemif , Aschcroft Jesse
Published: October 2024

Intraguild predator-prey relationships have been widely documented in amblypygids except for cannibalism. This behavior, despite its few records, may be more frequent than known. We present the first case for Panama.
Impact of prosperity gospel on the political aspect in selected neo-pentecostal movements in Karingani ward, Tharaka Nithi County, Kenya
Authors: Kinoti Evans , Kagema Dickson Nkonge , Orina Hellen Kagwiria
Published: October 2024

This study sought to investigates how prosperity gospel influences the political aspect of followers. The prosperity gospel is a teaching that is highly taught in neo-Pentecostal movements, finding acceptability and adaptability in the world, attracting many in neo-Pentecostal movements, hence, how does the gospel influence adherents' political aspect? Neo-Pentecostal movements have increased in numbers over the past decade in Karingani Ward Tharaka Nithi County, Kenya. The Functionalism Theory guided the study to analyse the influence of prosperity gospel on the political aspect of its followers. The study applied the descriptive survey design. Yamane’s formula was applied to obtain a sample size of 281 respondents. In addition, six pastors were selected from the churches, and the total sample was 294 respondents. The research instruments utilised were questionnaires and interviews. The study's findings revealed that prosperity teachings in Neo-Pentecostal movements had positive and negative impacts on the political aspect of followers, which is, voting and supporting specific political leaders and a given political party. On the other hand, the teaching of prosperity in these movements resulted in disunity in the church, ethnic tension, members leaving the church, and fights extending to communal daily living. The study concludes that the involvement of prosperity gospel preachers in political discussion in church significantly influences the political conviction, choices, voter turnout, and social interaction of members of these movements. Therefore, a policy formulation should be recommended that controls direct clergy influence on politics.
Marker-assisted foreground selection for identification of aromatic rice genotype to develop a modern aromatic line
Authors:   Advanced Seed Research and Biotech Centre (ASRBC), ACI Limited, Gulshan-1212, Bangladesh., Salam M. A. ,   International Rice Research Institute (IRRI), Bangladesh Ofice, Banani-1212, Bangladesh., Rafiq, Mr. , Diba, Sk. F. , Hossain Md.	M.
Published: October 2024

Marker-assisted backcrossing is one of the feasible methods to develop a new kataribhog type rice cultivar with semi dwarf and modern type plant character to cope with the challenge. The study was focused on the introgression of Badh2 QTL from kataribhog into some elite promising line-an early, agronomically suitable and susceptible variety. Backcrossing was done during T.Aman season; where G52, GOR509, G27, G49 and IR 93358:4-B-21-4-3-1RGA-2RGA-1-B were the recurrent parent and kataribhog was the donor parent. At 1st season 160 true F1 and then in the next season 134 BC1F1 Plant were developed, which were subjected to foreground selection; the first level of selection of marker assisted backcrossing program. The aim of foreground selection was to identify the introgressed lines. 141 BC1F1 populations were evaluated with tightly linked BADEX7-5 marker. A total of 134 heterozygous BC1F1 Plant were selected finally, which have alleles of both of the parents. Those introgressed lines could be efficiently used in further development of a stable modern type aromatic rice variety
Türkiye'nin MAAS Platformu İçin Veri ve Ödeme Yöntemi Standardizasyonu
Authors: Karacameydan İncemehmetoğlu Nihan , Tuğlu Kubilay , Çoşkun Özlem , İrdam Ömer Mahir , Avcı İsa , Kınacı Bahadır Furkan
Published: October 2024

Gelişen teknoloji ve ulaşıma duyulan ihtiyaçlar, ulaşım sistemlerinde gelişmelere neden olmuştur. Bu gelişmeler daha konforlu, güvenli, verimli ve erişilebilir sistemlere olan ihtiyacı ortaya çıkarmıştır. İlerlemelerin sonucu olarak akıllı ulaşım sistemleri ile ilgili gelişmeler ortaya çıkmış ve anlık izlenebilir ve yönetilebilir sistemler oluşturulmaya başlanmıştır. Ortaya konulan entegrasyon ve uçtan uca tüm seyahatin sağlanması için son yıllarda gelişen Hizmet Olarak Hareketlilik (MaaS) uygulamaları sektöre katkı sağlar duruma gelmiştir. Bu çalışmada, 2. seviye MaaS olarak geliştirilen uygulamanın bilgi edinme, rezervasyon ve ödeme işlemlerinde kullanılan uygulama bilgileri aktarılacaktır. Gerçekleştirilen uygulama şehirlerarası ve şehir içi toplu taşıma; paylaşımlı bisiklet, elektrikli bisiklet (e-bisiklet), elektrikli skuter (e-skuter) ve araç kiralama dahil olmak üzere çeşitli ulaşım seçeneklerini içermek ile birlikte, ilk aşamada 2 pilot şehirde, 10 ulaşım hizmet sağlayıcı ile 9 ulaşım modunda, yaklaşık 2000 toplu taşıma aracı ve yaklaşık 3500 paylaşımlı mikromobilite aracını kapsamaktadır. Ayrıca sistem uygulamaları ile mevcut kullanımda olan veri ve servis standartlarının yeterlilikleri tartışılacaktır. Bu çalışmada, Türkiye’nin ilk yerli ve milli 2. Seviye MaaS uygulaması olması planlanan TRota’da; şehirlerarası ve şehir içi toplu taşıma, paylaşımlı bisiklet ve e-skuter, araç kiralama dahil olmak üzere çeşitli ulaşım modlarını tek bir uygulamada kullanıcılara sunulmaktır. TRota uygulama entegrasyon çalışmasında oluşabilecek riskler için alınan önlemler ve alınması gereken ilave önlemler ayrıntılı olarak verilmiştir.
Optimization of Total Phenolic Content from Gynura Procumbens Leaves Under Oven and Microwave Drying
Authors: Wan Ahmadi Wan Farah Aina , Ali Imran Amirah Adibah , Syahir Mustapa Muhamad Shahmi , Ahmad So’bah , Bakar Suzaira
Published: October 2024

The optimization of the process variable; temperature, power, and drying time, under oven and microwave drying were studied for total phenolic content of Gynura procumbens leaves. The optimization conducted using response surface methodology central composite design of experiment. The optimum drying condition was obtained at 65.61°C at 10 hours with 201.78 mgGAE/g of TPC yield for oven drying while, for microwave drying was 436.19 Watt at 8.37 minutes with 12.24 mgGAE/g of TPC yield. The response surface methodology used in this study was able to predict the optimum drying condition for total phenolic content via linear and interaction mathematical model with higher adjusted coefficient determination , for both oven and microwave drying, 0.9383 and 0.7785, respectively. Hence, the models gave good prediction of the total phenolic content obtained from Gynura procumbens leaves under the experimental conditions used in this study. In addition, these outcomes are also expected to contribute to the production of shelf stable Gynura procumbens leaves which can be used for pharmacological purposes.
How Important are Employability Skills to Business Students?
Authors: ABOU HAMAD Maher , ABDELRAHIM Yousif
Published: October 2024

Research has indicated that educational institutions and the job market are facing many challenges, one being the required employability skills of graduates upon recruitment. This study aimed to explore how important employability skills are to business students. The research method used a sample of 123 questionnaires and 20 interviews of business students from one Saudi Arabian university. The main findings indicated that the participants considered all the mentioned employability skills highly to very highly important according to the students’ academic year and choice of future job but with no significant differences. However, Sophomore year students indicated a high positive significant difference in considering leadership as the most important skill over their junior and senior year counterparts. The findings further indicated the communication and leadership skills of high importance which contradicts the findings in the literature where life-long learning, tolerance, and language skills are considered of high importance. Additionally, the interview responses showed insufficient knowledge on the part of the students to develop their own skills to meet the market needs and maintain sustainable employment. Implications of the present study show that there is a need for urgent collaboration between educational institutions and job markets to identify, orient, and train students in needed employability skills. Future research on matching stakeholders’ employability skills is recommended.
The Impact of Transport Costs on Business Decision-Making in Rural Areas
Authors: CHIRIL Tatiana , Filimon Oleg , ZUGRAVU Gheorghe Adrian , Simionescu Cristian
Published: October 2024

Mobility challenges in rural areas can have a negative impact on economic and demographic development. People in these areas often have to move to urban areas to find quality jobs or services, which can lead to a decline in population, and economic activity. In this paper we analyze the factors influencing business decisions in rural areas. Public transport infrastructure based on short energy cycles using solar energy represents a solution to boost business decision management in rural areas.
BRAF and MEK Inhibitors for Active or Symptomatic Melanoma Brain Metastasis
Authors: CDA-AMC
Published: October 2024

This rapid review examines the clinical efficacy, effectiveness, and safety of BRAF and MEK inhibitors as a treatment for patients with active or symptomatic melanoma brain metastasis (MBM)
Three primary studies and 4 clinical practice guidelines met the eligibility criteria for this rapid review. No systematic reviews (SRs) were found.
There are very few studies examining the effectiveness and safety of BRAF and MEK inhibitors in patients with active or symptomatic MBM.
The limited number of primary studies available are of low quality and are subject to significant risk of bias. Three single-arm, low-quality cohort studies published since 2019 were identified: 2 providing data on median progression-free survival (PFS) (approximately 5 months), 2 providing data on overall survival (OS) (approximately 7 to 9 months), and the third providing narrative descriptions only. Adverse effects were reported in 1 study. No comparative studies were located.
The 3 primary studies reported that patients may survive for up to 5 months without their symptoms worsening, and their OS rates were between 7.4 months to 9.5 months after receiving BRAF and MEK inhibitor combination therapy. In 1 study, common side effects included fever, rash, and fatigue, and some patients stopped treatment primarily because of fever and abnormal liver function.
The clinical practice guidelines considered our patient population, but the resulting recommendations did not differentiate between patients with and without active or symptomatic MBM or did not refer specifically to BRAF and MEK inhibitors. Instead, most recommendations focused on other treatments, such as surgery.
Bimekizumab (Bimzelx)
Authors: CDA-AMC
Published: October 2024

Reimbursement reviews are comprehensive assessments of the clinical effectiveness and cost-effectiveness, as well as patient and clinician perspectives, of a drug or drug class.
The assessments inform non-binding recommendations that help guide the reimbursement decisions of Canada’s federal, provincial, and territorial governments, with the exception of Quebec.
This review assesses bimekizumab (BIMZELX), 160 mg/mL, solution for injection, subcutaneous injection.
Indication: The treatment of adult patients with active ankylosing spondylitis who have responded inadequately or are intolerant to conventional therapy.
"ANALYSIS OF CASES OF VOLUNTARY RENUNCIATION AND FORCED TERMINATION OF A CRIME"
Authors:   ", Kamalova Dildora ,   Tashkent State University of  Law "
Published: October 2024

"Abstract. A voluntary renunciation to commit a crime is considered when a person stops doing preparatory actions or directly aimed at the commission of an offence, knowing that it may be ended and that it could lead to criminal consequences. The specificity of a voluntary renunciation to commit a crime is that the act is not completed due to circumstances depending on the person. A person, on the basis of his inner feeling, being aware of the consequences, inevitably ceases the beginning of a socially dangerous, wrongful act. It is for this reason that the law provides for the absence of liability of voluntary objectors. However, one of the important questions is to determine whether the abandonment of the crime was «voluntary», to study the factors that caused the person to stop the crime, and on this basis to give a correct legal assessment of the act. It is therefore difficult in judicial and investigative practice to distinguish between voluntary renunciation of a crime and compulsory punishment of a crime. This research article is focused on examining cases of voluntary and forced crime termination, analyzing their unique features, and determining cases that do not involve liability. The author studied the factors leading to the cessation of crime, grouped them according to their similarities, and analyzed them in detail with practical examples. They developed conclusions on the development of the theory of criminal law. "