bluuebunny/crossref_metadata_2025 huggingface dataset:
Incidence of Appendicular Bone Fracture in Dogs and Cats: Retrospective Study at Veterinary Hospital of Cairo University and some Private Clinics in Egypt
Authors: Abo-Soliman Abeer Ali Mahmoud , Ahmed Ahmed Elsayed , Farghali Haithem Ali Mohamed Ahmed
Published: October 2021

Appendicular bone fractures in small animal practice constitute a major challenge facing veterinary orthopedic surgeons concerning affected limb and bone as well as the extent of tissue damage, site, and shape of the fracture line. Therefore, this retrospective study was designed to provide descriptive data at referral veterinary teaching hospital, faculty of veterinary medicine, Cairo University, and some private pet clinics in Cairo district, Egypt to identify and determine the prevalence of appendicular fractures arising from trauma in dogs and cats treated from January 2017 to January 2020, and emphasizing the information that characterized the population (breed, age, gender, and animal size). The investigated fractures were classified according to the specific limb (forelimbs / hind limbs), specific bone fractures (Humerus, radius and ulna, femur, tibia and fibula, and the other bones), extent of tissue damage (open or closed and incomplete or complete), site (proximal, diaphyseal or distal zones), number (single or comminuted), and the direction of the fracture line (transverse, oblique or spiral). From the obtained data, it could be concluded that there was a high incidence of the appendicular long bones concerning the different bone fractures with significantly higher records in dogs, compared to cats. The highest records of fracture were in mongrel dogs, and cats as rescued animals. Excluding mongrel dogs and cats, the highest incidence of fracture-cases in dogs was recorded in Miniature breeds and svelte breeds for cats. Male dogs and cats showed a higher incidence than females. The bone fracture mostly occurred in dogs younger than one-year-old, and cats aged one to three years. A fracture in the hindlimbs was more significant than forelimbs with the highest incidence in femoral bone among both dogs and cats. The percentage of open fractures were more common in cats than dogs. Incomplete fractures were recorded more frequently in dogs than cats. In dogs, the most common fractures in the femur, tibia/fibula, humerus, and radius/ulna were complete comminuted diaphyseal femoral, complete oblique diaphyseal tibial/fibular, complete transverse distal humoral, and complete transverse diaphyseal radial/ulnar fractures respectively. Moreover, cats were complete transverse distal femoral, complete oblique diaphyseal tibial/fibular, complete spiral diaphyseal humoral, and complete transverse distal radial/ulnar fractures. In conclusion, appendicular bone fracture among dogs and cats referred to the veterinary teaching hospital, Cairo University and some private clinics in Egypt showed high incidence (87% in dogs and 71.8% in cats) out of total fracture cases and this incidence correlated with some predisposing factors (including breeds, weight, age, and gender) and causative agents that resulted in different types of appendicular fractures.
The Effect of Dietary Supplementation of Cod Liver Oil on Ratio of Saturated and Unsaturated Fatty Acids in Giant Prawn (Macrobrachium rosenbergii) Meat
Authors: Marzuki Lutfi , Agustono . , Rahardja Boedi Setya
Published: October 2021

The existence of feed plays an important role in aquaculture activities. This is due to the dominant influence on fish feed growth. Feeding with the right nutritional components can produce healthy and high-quality fish products. One of the nutrients needed by fish is fatty acids. In fact, the provision of fatty acids, one of which is not in the meat, has an important influence. So, this study aims to determine the effect of adding cod liver oil to commercial feed on the ratio of saturated and unsaturated fatty acids to the meat of giant prawn. This research was conducted experimentally with a completely randomized design. The treatment is given a dose of cod liver oil 0% (control), and treatments 1-4 use 3% dose addition to each treatment. On the other hand, in the data analysis stage, the researchers used ANOVA and continued with the Duncan’s test. Based on the results, the study notes that the administration of cod liver oil in commercial feed does not affect the decreasing content of saturated fatty acids in giant prawn meat. On the other hand, the results also showed that the best ratio was found in treatment 4 at a dose of 12%. Therefore, it is concluded that the provision of nutrients for feed related to fatty acids in the pole has not reduced the content of saturated fatty acids. As well as, the best ratio of saturated fatty acids and unsaturated fatty acids was 1.21:1 with cholesterol content of 88.34 mg/dl and this ration resulted by the greatest growth rate in present study.
Moderating Effect of Social Capital on the Relationship Between HRM Practices and the Performance of Companies Listed on NSE
Authors: Diriye M. A. , KObonyo P. , Munjuri M. , Wainaina G.
Published: October 2021

Accessibility to broader information sources as well as the advancement of the quality of information, relevance, and timeliness is facilitated by social capital. These circumstances pave the way for individuals to improve their knowledge by interacting with coworkers daily. The study's main objective was to establish the moderating effect of social capital on the relationship between HRM practices and the performance of companies listed on NSE. The research was guided by the social-capital theory. This research utilized a descriptive research design and applied the positivist approach. The population of the study included 65 companies listed on the Nairobi Stock Exchange (NSE), and it employed both primary and secondary data, with secondary data consisting of the financial indicator Return on Assets (ROA). Questionnaires were employed to gather primary data, and descriptive and inferential statistics were utilized to analyze the data. The method utilized was linear regression. According to the findings, social capital has a moderating influence on the link between HRM practice configurations and company success on the NSE. This study recommends that training and development efforts be consistent, and that research institutes guarantee that training provided to employees is relevant to their needs. As a result, they should undertake a training need analysis to determine the program's relevance to learners. Research institutes must also ensure that they have the best possible resources.
Distribution of the areas and heights of the radar echoes from convective clouds around Delhi during monsoon season
Authors: CHATTERJEE R. N. , PRAKASH PREM , ALI KAUSHAR
Published: October 2021

Distributions of areas and heights of radar echoes from convective clouds, observed in Delhi region during six monsoon seasons, 1967-1972, were studied. Stratification of the echoes according to their areas into three different scales, namely scale D scale(<100 km2), C scale (101-1000 km2) and B/C scale (> 1000 km2) indicated predominance of the echoes in D scale, with relatively small percentage in. C and B/C scales. Frequency distributions of areas and heights of these echoes tended to be lognormally distributed.
Analisis Implementasi Sistem Proteksi Kebakaran Aktif, Sarana Penyelamatan Jiwa Dan Tanggap Darurat Di Gedung Promoter Polda Metro Jaya Tahun 2021
Authors: Ilham_bintoro10
Published: October 2021

Introduction: Promoter Polda Metro Jaya Building is one of the state-owned buildings which must complete Occupational Health and Safety (OHS) requirements, have a fire protection system, life saving equipment, and emergency response due to the regulation. The purpose of this research is to know The Impelentation of The Fire Protection Active System, Life Saving Equipment, and Emergency Response at Promoter Polda Metro Jaya Building according to Ministerial Regulation No. 26 2008. Methods: This research is a qualitative research using triangulation method by interviewing, observating, and resourcing. The Informants of this research are Head of Managing Coordinator, Technician Supervisor, and The Technicians. Results: The results of the research are the implementation of fire protection active system has already appropriated to Ministerial Regulation No. 26 2008 with 90,5 % suitability, the implementation of life saving equipment has already appropriated to Ministerial Regulation No. 26 2008 with 94% suitability, the implementation of fire emergency response has already appropriated to Ministerial Decree 186/MEN/1999 with 46,15% suitability. Discussion: The suggestions according to priority scale are the manager makes a policy about the prevention and repression of the fire disaster, SOP of emergency response, forms emergency response team, and maintains, checks, and evaluates the fire protection active system and life saving equipment regularly.
Teori Belajar Humanistik Dan Implikasinya Pada Maharah Istima'
Authors: Ma’rifatul Faiqoh Naning , Baroroh R. Umi
Published: October 2021

Recently, many educational theories grow up based on the assumptions in some problems. This article explores humanistic learning theory and its implications for learning Arabic at maharah istima ', using library research, since the data and information were collected in the form of a continuous library with discussion, then the researcher analyzed the data using content analysis method. The results shows that the application of  maharah istima '  learning Arabic includes learning objectives, learning models, using media, culture and students’ background. Carl Rogers' humanistic theory emphasizes deep humanity, does not contain selfish, individualistic elements or authoritarian, they do not have to follow our opinion, so this theory focuses on the student center, that focused on the cognitive, affective and psychomotor aspects by giving students their rights, being humanized, recognized and accepted, from which students will be optimistic in voicing contents of their mind.
USE OF EVIDENCE IN THE POLICYMAKING PROCESS. QUALITATIVE COMAPARATIVE ANALISYS OF 17 DEVELOPED COUNTRIES
Authors: Gędek Wojciech
Published: October 2021

In the last two decades the Evidence-Based Policy has become one of the most discussed approaches in the public policy circles. However, the current literature lacks systematic comparative studies of evidence use across different national contexts. Using the crisp-set Qualitative Comparative Analysis (csQCA) method, the author of the article compared seventeen developed states to identify and interpret combinations of conditions determining the presence of the Evidence-Based Policy (EBP) in the field of climate policy. Obtained results indicated that the combination of the presence of low public debt and the presence of high level of social capital is an important explanatory configuration for the presence of Evidence-Based Policy among compared cases.
PHYSICAL INVESTMENT FINANCING IN THE CZECH CORPORATE SECTOR
Authors: Stępień Małgorzata
Published: October 2021

The aim of this article is to identify the structure of physical investment financing in the Czech corporate sector. The data used in the conducted analyzes are derived from national accounts and more specifically the two accounts included in the accumulation accounts, ie.: the capital account and financial account. The article uses the methodology of net sources of finance initially developed by C. Mayer. It uses the flow of funds rather than stock data.
Configurando o Google Contas Inativas: percurso cognitivo e outras trilhas avaliativas
Authors: Lira Maria Fernanda , Maciel Cristiano , Trevisan Daniele , Bim Sílvia Amélia
Published: October 2021

Uma grande quantidade de bens e ativos digitais são produzidos diariamente nos diversos espaços na internet. Após a morte dos usuários, esses bens e ativos constituem o seu legado digital e precisam de um destino. Atualmente, muitos sistemas têm buscado soluções para o gerenciamento de legado digital pós-morte. Este estudo tem como objetivo avaliar o sistema interativo do Google Inactive Account Manager (IAM) ou Contas Inativas, por meio do método de inspeção mPC (método de Percurso Cognitivo) e comparar os resultados dessa avaliação com outros fornecidos na literatura. Os resultados evidenciam que os métodos de avaliação em mPC também contribuem para melhorar a interação do usuário com o sistema e apontar questões que precisam ser aprimoradas.
Plattformregulierung durch europäische Werte: Zur Bindung von Meinungsplattformen an EU-Grundrechte
Authors: Denga Michael
Published: October 2021

Der Entwurf zum Digital Services Act zielt auf das Problem „schlechter Inhalte“ auf digitalen Meinungsplattformen. Wesentliches Element ist die Bindung der Moderatoren von Nutzerinhalten an europäische Werte in Form von EU-Grundrechten. Der Ansatz ist wegen der Dezentralität schlechter Inhalte grundsätzlich konsequent. Eine horizontale Wirkung der Meinungsfreiheit steht allerdings in Widerspruch zur Rechtsprechung des EuGH und kann nicht durch einen Sekundärrechtsakt angeordnet werden. Zudem werden die eigenen Grundrechtspositionen von Meinungsplattformen strukturell verkannt.
U.S. Emissions Trading and what it can teach us for a Post-Kyoto World
Authors: Krause Fabian
Published: October 2021

Major CO2 emitters such as individual states of the USA, the People's Republic of China and the European Union continue to rely on emissions trading systems to reduce CO2 emissions. Against this background, this thesis examines four emissions trading systems in the USA. For this purpose, the legal and economic fundamentals of emissions trading are presented in detail. Subsequently, emissions trading systems are analyzed from an economic as well as a legal point of view based on criteria defined for this purpose and the results are embedded in the context of national and international law. For this purpose, the author conducts extensive basic research by processing the available emissions and trade data.
SURGICAL MANAGEMENT OF A DIGESTIVE TRACT HERNIA IN A FREE RANGING WILD MARSH FROG (PELOPHYLAX RIDIBUNDUS)
Authors: Sailler Anaïs , Chai Norin , Huberdeau Pierre , Sabatier Laurent , Scotti Thierry , Boistel Renaud
Published: October 2021

A wild-caught mature female marsh frog (Pelophylax ridibundus) was presented for a left-sided dorsal swelling. No other abnormalities were detected during the examination. Fine needle aspiration was non-diagnostic. Baseline hematological and biochemical analyses were within normal range and medical imaging did not provide further useful information. Surgical exploration under general anaesthesia was performed. The swelling was confirmed to be a digestive tract hernia protruding through a breach of the dorsal muscles and coelomic membrane. Reduction was made difficult by the presence of multiple adhesions between the herniated tissue and the coelomic membrane, suggesting a relatively chronic lesion. A traumatic cause was hypothesised. One month later, the animal was healthy and was released back in the wild. Hernias in amphibians are poorly reported in literature, and are only ventral. To the best of authors’ knowledge, a dorsal hernia has never been described in a captive or a free ranging amphibian before.
Replies to my Critics
Authors: Talisse Robert B. ,   Philosophy Documentation Center
Published: October 2021

The four critical essays responding to Overdoing Democracy exhibit a thematic progression. Some take issue with the conception of democracy that underlies my book, while others emphasize my diagnostic and prescriptive accounts. This essay follows that progression in addressing my critics.
Luz da Razão. Para um a Fundamentação Onto-Metafísica
Authors: Blanc Mafalda ,   Philosophy Documentation Center
Published: October 2021

Se a crise da racionalidade é uma constante da sua história e uma implicação natural do carácter fragmentário e conjectural do conhecimento, já a sua derrapagem céptica se afigura mais preocupante e insana, sobretudo quando oriunda daqueles sectores da cultura que, por inerência e vocação, mais deveriam velar pela preservação da validade de critérios cognitivos e mora is de indiscutível interesse social. É este, a nosso ver, um estado de coisas que pode e deve ser combatido pelo retorno às fontes intuitivas e onto lógicas da racionalidade. Tal é, pelo menos a breve trecho, a tese que neste artigo se defende em uníssono com a fenomenologia. Assim, após revisitar as concepções clássica e moderna de verdade e relevar de vários modos a natureza auto-refutante do relativismo, o presente texto advoga a normatividad e da razão alegando que a verdade, na sua formalidade, se dá a pensar não apenas como índice de si própria mas ainda da estrutura do próprio ser na sua aprioridade transcendente e ideal.
O Argumento Antropológico. Henrique de Gand e Santo Anselmo
Authors: Santiago de Carvalho Mário ,   Philosophy Documentation Center
Published: October 2021

Henrique de Gand foi um leitor atento e critico de Santo Anselmo. O presente artigo persegue essa relação, mormente para o caso do argumento anselmiano, mas prefere apostar numa leitura do argumento metafisico de Henrique, tal como o apresentou J. Gómez Caffarena, a fim de concluir que, mais do que um problema de Deus, em filosofia, importa falar do mistério de Deus.
Rectitudo e Libertas em de Libertate Arbitrii de Santo Anselmo
Authors: Rosa José M. Silva ,   Philosophy Documentation Center
Published: October 2021

O liberum arbitrium, para Santo Anselmo, não pode residir no poder permanente de pecar e de não pecar (posse peccare et non peccare), porque tal definiçao tomaria inútil «a graça, a predestinação e a presciencia de Deus» (DLA, I, 207, 1-2). Por outro lado, se nós não tivéssemos sempre essa potestas, o pecado não poderia ser-nos imputado porque nós pecaríamos «sine libero arbítrio». Procurando separar esta alternativa, que lhe parece armadilhada, Santo Anselmo busca uma definição de libertas arbitrii independente do poder negativo de pecar (potestas peccandi) e, a partir da distinção entre voluntas propter se (instrumentum volendi) e voluntas propter aliud (usus sive opus volendi), julga encontrá-la na seguinte: a libertas arbitrii é «o poder de guardar a rectitude da vontade pela própria rectitude» (DLA, III, 212, 19-20: «potestas servandi rectitudinem voluntatis propter ipsam rectitudinem»), poder que exprime a exacta e positiva noção da «justiça original». À luz de tal definição transcendental de libertas arbitrii, comum a Deus, aos anjos e aos homens, pode Anselmo avançar a tese teologicamente mais ousada do opúsculo: nem Deus, apesar de poder «reduzir a nada uma substância que Ele fez do nada», é capaz de «separar a rectidão de uma vontade que a possui» (DLA, VIII, 220, 13-15).
Anterior or Posterior Prostate Cancer Tumor Nodule Location Predicts Likelihood of Certain Adverse Outcomes at Radical Prostatectomy
Authors: Hayee Amin , Lugo Isabella , Iakymenko Oleksii A. , Kwon Deukwoo , Briski Laurence M. , Zhao Wei , Nemov Ivan , Punnen Sanoj , Ritch Chad R. , Pollack Alan , Jorda Merce , Stoyanova Radka , Parekh Dipen J. , Gonzalgo Mark L. , Kryvenko Oleksandr N.
Published: October 2021

Context.—

Effect of tumor nodule (TN) location in the prostate on adverse radical prostatectomy (RP) outcomes is not well studied in contemporary cohorts.

Objective.—

To investigate the significance of TN location with respect to extraprostatic extension (EPE), seminal vesicle invasion (SVI), and positive surgical margin (SM+) in 1388 RPs.

Design.—

Each TN at RP was independently graded, staged, and volumetrically assessed. TNs with at least 80% of their volume occupying either the anterior or posterior part of the prostate were categorized accordingly and included in our study, while all other TNs were excluded.

Results.—

A total of 3570 separate TNs (median = 3 per RP; range = 1–7 per RP) were scored. There were 1320 of 3570 (37%) anterior TNs and 2250 of 3570 (63%) posterior TNs. Posterior TNs were more likely to be higher grade, and exhibit EPE (18% versus 9.4%) and SVI (4% versus 0.15%), all P < .001. Anterior TNs with EPE were more likely to exhibit SM+ than posterior TNs with EPE (62% versus 30.8%, P < .001). TN location, grade, and volume were significant factors associated with adverse RP outcomes in our univariable analysis. When we controlled for grade and tumor volume in a multivariable analysis using anterior TN location as a reference, posterior TN location was an independent predictor of EPE and SVI and was less likely to be associated with SM+ (odds ratio = 3.1, 81.5, and 0.7, respectively).

Conclusions.—

These associations may be useful in preoperative surgical planning, particularly with respect to improving radiographic analysis of prostate cancer.
On estimation of stress-strength reliability using lower record values from odd generalized exponential: Exponential distribution
Authors: Mohamed M.O. , Reda Ahmed
Published: October 2021

This research paper aims to find the estimated values closest to the true values of the reliability function under lower record values, and to know how to obtain these estimated values using point estimation methods or interval estimation methods. This helps researchers later in obtaining values of the reliability function in theory and then applying them to reality which makes it easier for the researcher to access the missing data for long periods such as weather. We evaluated the stress-strength model of reliability based on point and interval estimation for reliability under lower records by using Odd Generalize Exponential-Exponential distribution (OGEE) which has an important role in the lifetime of data. After that, we compared the estimated values of reliability with the real values of it. We analyzed the data obtained by the simulation method and the real data in order to reach certain results. The Numerical results for estimated values of reliability supported with graphical illustrations. The results of both simulated data and real data gave us the same coverage.
Habilidades comunicativas y de relación en la educación superior de disciplinas dirigidas al asesoramiento
Authors: Valencia-Naranjo Nieves , Robles-Bello María Auxiliadora
Published: October 2021

Las habilidades comunicativas y de relación son relevantes en la actividad académica y profesional en carreras dirigidas a la ayuda de otros. La planificación de actividades formativas dirigidas a la interacción con otros (ej. pares) facilita la adquisición de estas habilidades, especialmente cuando se impulsa mediante la retroalimentación juicios evaluativos más ajustados y la regularización del proceso de aprendizaje. Disponer de instrumentos que faciliten una retroalimentación eficaz contribuye a la planificación de estas tareas formativas, herramientas que deben informar de habilidades que participan en el asesoramiento. Además, facilitan la evaluación eficiente de la adquisición y aprendizaje de amplios grupos de alumnos. Uno de esos instrumentos puede ser el Cuestionario de Habilidades Comunicativas (HABICOM). En este trabajo, se examinaron diversos aspectos metodológicos relacionados con el uso de instrumentos de evaluación de las habilidades comunicativas en situaciones de interacción. Los resultados obtenidos en los objetivos propuestos sugieren que: (1) El análisis factorial confirmatorio indica que la estructura factorial del HABICOM y niveles de fiabilidad y validez son aceptables una vez se eliminan algunos ítems; (2) Estas habilidades auto-percibidas son similares en alumnos de Psicología y Trabajo Social; (3) Existe relación en la percepción de las habilidades comunicativas mostradas durante la interacción en un formato auto-aplicado o hetero-aplicado; (4) La percepción del compañero medida con el HABICOM correlaciona con la percepción de las habilidades de ayuda durante la interacción; (5) El análisis de las habilidades del alumno mediante video se relaciona con las habilidades identificadas por el compañero.
Screening asylum seekers in Denmark for torture using a structured questionnaire
Authors: Munk-Andersen Ebbe , Toftgaard Bettina , Modvig Jens
Published: October 2021

The United Nations Committee against Torture recommends systematic torture screening throughout the asylum process.   The goal of this study is to evaluate the introduction of a structured questionnaire, coding for torture according to the definition from United Nations Convention Against Torture (UNCAT). This screening for torture is now an integrated part of the medical reception of newly arrived asylum seekers

The screening was carried through during a 2 years period as a part of the routine health screening, and alleged torture victims were referred to further medical examination and offered assistance to carry information about the torture to the Immigration Service. The participation rate was 85.2%, and torture was reported among 27.8% of the males, with a mean of 21.2% among both sexes.

Key words: Torture, screening, questionnaire, asylum seekers, UNCAT
The half-widows of Kashmir
Authors: Haq Inamul
Published: October 2021

Women all over the globe have to struggle for their sustenance as well as for justice. Most of such narratives are common in conflict zones, where women have to bear unfavourable circumstances, indifferent society, absence of laws, poor rehabilitation mechanism and unresponsive government machinery. Women whose husbands have been subjected to enforced ‘disappearances’ are often called ‘half widows’. Half widows illustrate one of the starkest forms of the general insecurity in Kashmir. The wives and mothers of men who have ‘disappeared’, who have been picked up and taken into custody by the authorities, or killed, remain in a tragic state of suspense. They are unaware of their true marital identity and in the complete absence of information on the fate of their loved ones. The half-widows do not get to know about their husbands, whether they are dead or alive and live in the hope that one day they may return home. However, they continue to live their lives, seeking livelihoods, supporting their children financially and emotionally. The absence of any assured rehabilitation measures renders them emotionally bruised, psychologically traumatized, economically disturbed and even physically crippled. These half-widows continue to suffer in silence, the lack of a structured database is painfully evident as no thorough record has been maintained or comprehensive survey conducted to measure the problem realistically. Therefore, in order to seek recognition, and thus redress, this paper documents the saga of such women in the context of liminality and exception.
Forensci Case Series
Authors: Lin James , McVane Ben , Soley Berta
Published: October 2021

Welcome to the Torture Journal Forensic Case Series, a new section of the Torture Journal. Through this Series, we aim to provide a source of information and continuing education for health and legal practitioners involved in the forensic evaluation of survivors of torture.

 

Cases in this section may describe unique or uncommon physical and psychological findings, illustrate barriers to a thorough evaluation, or present features that make effective articulation of a survivor’s claim challenging. Case discussions aim to provide further information about findings or reflections on how challenges were approached. We also aim to address common misconceptions about the clinical evaluation and the experience of torture. As one of the benchmarks for our discussions, we apply the principles and standards of the United Nation’s Istanbul Protocol. 

           

We hope that you will find these case studies to be a useful resource for your work with survivors of torture. 

 

Yours Truly,

 

Guest Editors:

Prof. Dr. Ben McVane, Senior Medical Educator, Libertas Center for Human Rights

Prof. James Lin, Istanbul Protocol Programme Coordinator, IRCT
Two shades of malignancy in a psoriatic patient
Authors: Chaabani Meryam , Jaber Kahena , Rebhi Faten
Published: October 2021

Psoriasis is a chronic inflammation of the skin, affecting approx. 120 million people worldwide. The risk of developing skin cancer in psoriatic patients has been stressed, although with a significant amount of conflicting data in the literature. The most consistent findings suggest that psoriatic patients are at an increased risk of non-melanoma skin cancer. An increased risk of melanoma has not been well established. Herein, we report the case of a patient with a history of pustular psoriasis present since the age of ten, who developed an SCC and a melanoma, and discuss the etiopathology of this association.
Anti-corruption denunciation: methodological problems, foreign experience, and Russian prospects
Authors: Trofimov Egor Viktorovich
Published: October 2021

This article is dedicated to the institution of denunciation as a specific form of disclosure of illegal and unfair practices. For determination of the conceptual legal meaning of denunciation and its prospects for modern Russia as anti-corruption legal institution, this article coordinates the interdisciplinary scientific results of research on denunciation, analyzes and summarizes the international (UN, EU) and national (United States, Great Britain, South Korea, Brazil, China, Albania, Kazakhstan, and Ukraine) regulatory approaches towards denunciation, and similar forms of disclosure of offenses. The article reveals the current state of the Russian legislation in this sphere. The research employs the methods of dogmatic analysis, comparative-legal and systemic-analytical toolset. The author correlates denunciation and denunciator with such concepts as “denouncement”, “actio popularis”, “reporting party”, “informant” and “whistleblower”; determines the twelve characteristics of denunciation, which collectively define it as a special form of information disclosure. The conclusion is made that the variants of legal regulation of denunciation are built around or within such issues as the protection of denunciator, his interaction with the authorized entities and remuneration, as well as the conclusion on the absence of specific legal means in the current Russian legislation that ensure denunciation as the social institution. The author formulates recommendations on amending the labor, administrative, criminal and procedural legislation aimed at implementation of measures for protecting the denunciators.
Proposed therapy, developed in a Pcdh15-deficient mouse, for progressive loss of vision in human Usher syndrome
Authors: Sethna Saumil , Zein Wadih M , Riaz Sehar , Giese Arnaud PJ , Schultz Julie M , Duncan Todd , Hufnagel Robert B , Brewer Carmen C , Griffith Andrew J , Redmond T Michael , Riazuddin Saima , Friedman Thomas B , Ahmed Zubair M
Published: October 2021

Usher syndrome type I (USH1) is characterized by deafness, vestibular areflexia, and progressive retinal degeneration. The protein-truncating p.Arg245* founder variant of PCDH15 (USH1F) has an ~2% carrier frequency amongst Ashkenazi Jews accounts for ~60% of their USH1 cases. Here, longitudinal phenotyping in 13 USH1F individuals revealed progressive retinal degeneration, leading to severe vision loss with macular atrophy by the sixth decade. Half of the affected individuals were legally blind by their mid-50s. The mouse Pcdh15R250X variant is equivalent to human p.Arg245*. Homozygous Pcdh15R250X mice also have visual deficits and aberrant light-dependent translocation of the phototransduction cascade proteins, arrestin, and transducin. Retinal pigment epithelium (RPE)-specific retinoid cycle proteins, RPE65 and CRALBP, were also reduced in Pcdh15R250X mice, indicating a dual role for protocadherin-15 in photoreceptors and RPE. Exogenous 9-cis retinal improved ERG amplitudes in Pcdh15R250X mice, suggesting a basis for a clinical trial of FDA-approved retinoids to preserve vision in USH1F patients.
Modality-specific tracking of attention and sensory statistics in the human electrophysiological spectral exponent
Authors: Waschke Leonhard , Donoghue Thomas , Fiedler Lorenz , Smith Sydney , Garrett Douglas D , Voytek Bradley , Obleser Jonas
Published: October 2021

A hallmark of electrophysiological brain activity is its 1/f-like spectrum – power decreases with increasing frequency. The steepness of this ‘roll-off’ is approximated by the spectral exponent, which in invasively recorded neural populations reflects the balance of excitatory to inhibitory neural activity (E:I balance). Here, we first establish that the spectral exponent of non-invasive electroencephalography (EEG) recordings is highly sensitive to general (i.e., anaesthesia-driven) changes in E:I balance. Building on the EEG spectral exponent as a viable marker of E:I, we then demonstrate its sensitivity to the focus of selective attention in an EEG experiment during which participants detected targets in simultaneous audio-visual noise. In addition to these endogenous changes in E:I balance, EEG spectral exponents over auditory and visual sensory cortices also tracked auditory and visual stimulus spectral exponents, respectively. Individuals’ degree of this selective stimulus–brain coupling in spectral exponents predicted behavioural performance. Our results highlight the rich information contained in 1/f-like neural activity, providing a window into diverse neural processes previously thought to be inaccessible in non-invasive human recordings.
Application of Position-Based Work as a Marketing Face in a Public Institution
Authors: Kendirli Hulya Cagiran
Published: October 2021

When the performance is evaluated as a terms in public administration that is expressed as the ability to achieve a given job at the desired level. For many years the private sector has been working on positive performance on their works. In recent years, both in the world and in Turkey, public institutions have made performance a priority in their work. The evaluation of the performance as a term of performance is more important in state economic enterprises. In this context, position-based work and performance management were chosen as subjects for research in a public institution. Within the scope of the research, a questionnaire was applied in order to evaluate the performance measurement for marketing in the relevant public institution. Within the scope of the study, all employees of the institution (4200 employees) were requested to be included in the survey. However, among the applied questionnaires, the number of returned and evaluable questionnaires was 480. According to the results obtained from the research, it has been concluded that the employees make a positive contribution to the company performance in terms of marketing. When the financial statements of the institution are analyzed, it is seen that this situation reflects the truth.
The Effect of Educational Intervention on Rational Prescribing in Public Health Facilities in Selected Local Government Areas of Rivers State: An Interventional Study
Authors: Owhonda Golden , Emeka Anyiam Felix
Published: October 2021

Background: Despite progress made so far in identifying intervention models to improve drug use, irrational use of drugs has remained a serious global health problem. The study intends to determine the effectiveness of an educational intervention on rational prescribing among prescribers in selected local government areas of Rivers State.

Methods: This was a quasi-experimental study that measured the effect of educational intervention on rational prescribing of drugs among prescribers in public health facilities in two selected Local Government Areas (LGA) of Rivers State: Ikwerre LGA (KELGA) which served as the control and Port Harcourt LGA (PHALGA) which served as the intervention by using cluster sampling with randomization. Paired data were analysed using McNemar’s Chi-square test and the paired t-test. The level of significance was set at P≤ 0.05. The EPI-INFO version 7.02 statistical software was used in the analysis.

Results: Findings showed that the largest category of prescribers was nurse/midwives representing 48.61% and 44.4% in the intervention and control LGA respectively. There was an improvement in the knowledge and attitude of respondents in the facilities in the intervention LGA at one month and three months post-intervention (P<0.05). The average number of drugs per encounter (ANDPE), the percentage encounters with an antibiotic (PEA), the percentage encounters with an injection (PEI) were lower for the interventions group compared to the control (P<0.05). Percentage generic drug prescription (PGD) was higher in the intervention group compared to the control (P=0.001).

Conclusion: Educational intervention was an effective and sustainable means of improving rational prescribing in the state. Update courses and continuing medical education on rational drug use should be held periodically for health care professionals by the State and National Primary Health Care Development Agency as well as other interested stakeholders.
Phenological Study of Elaeis guineensis (Jacq.) Growing in Ihiala, Anambra State, South-East Nigeria
Authors: M. Angela Ochia, , U. Kenneth Ekwealor, , S. Victor Njom , A. Onyinye Mbaukwu , F. Chisom Iroka,
Published: October 2021

The aim of the study was to provide a phenological data and baseline information on the phenology of Elaeis guineensis Jacq. The study was conducted with exotic species at Ihiala, South-East, Nigeria, a tropical climate. The initiation and completion of different phenophases of the tree, such as budding, leafing, flowering, fruiting and ripening were recorded at two weeks interval. The combination of the principal growth stages and the secondary growth stages produced 2-digit codes, were used to delineate the time-dependent phenophases. The results revealed that E. guineensis showed a cyclical and seasonal appearance of the phenophases observed in the course of the year. Bud formation and leaf development phenophases were very gradual and steady across the months observed. Peak flowering time of August through November and peak ripening time of April was recorded in this study. Also, the study revealed that difference existed in the extent of phenophases of the observed species. The study also showed that E. guineensis belong to the family (Arecaceae) had different time frames for the phenophases. It is concluded that the phenological records obtained from the study can be very useful in planning and management of orchards, and can provide reference records in tracing changes in the phenology of E. guineensis in the future.
Physiology and Rumen Microbial Ecology of Goats Fed Municipal Organic Solid Wastes Treated with Diastic Microbes from Snail (Achatina achatina)
Authors: Christopher Agboje Agida, , Ekpenyong Nsa Essien , Essien John Uduakobong , Ihuoma Adje Constance , Chukwuemela A. N. , Adanma Ukonu Blessing , Mbanefo Anigbogu, Nnamdi
Published: October 2021

The experiment was conducted with the objective of providing more information on the physiology and rumen microbial ecology of goats fed municipal organic solid waste treated with Diastic microbes of snails (Achatina achatina). The study was on the treated and untreated municipal organic solid waste as components of experimental diet. Balanced rations containing diets; A = 45% untreated municipal organic waste (UMOW), B = 45% treated municipal organic waste (TMOW), and C = 70% treated municipal organic waste (TMOW), with wheat offal, palm kernel cake, and molasses used to balance the diets. Where grass/legume ratio of 3 parts of Panicum maximum and 1 part of Centrocema were fed across treatments at the same proportion. The three rations were fed to 18 unsex Red Sokoto goats aged between 6 to 7 months, with an average weight of 8.01±2.50kg. They were housed in pens, on a floor space of 0.5 to 0.75m2 in a completely randomized designed experiment replicated six times and fed for a period of 52 days. The results were separated according to the parameters of rumen physiology (pH, total volatile fatty acids, acetic, propionic, butyric acids and ethanol, and rumen ecology (bacteria, protozoa, and fungi, which are mainly anaerobic microbes). The investigations revealed that microbial (bacteria, protozoa and fungi) load counts were significantly (p<0.05) influenced by dietary treatments. While the total volatile fatty acids (TVFA), acetic, butyric and propionic increased (p<0.05) except for the TVFA and the propionic acid that showed numerical (p>0.05) increased levels of (TMOW). The pH levels improved (p>0.05) between 6.7 to 6.8 where the rumen electrolytes (Ca, Na and K) increased (p<0.01) with increased levels of TMOW. Rumen moisture, dry matter and fat content were (p<0.01) influenced by TMOW diets while ash content was (p<0.01) influenced by the TMOW. Crude protein, ether extract, crude fibre and carbohydrate were not affected (p<0.01; p<0.05) affected. It is good to note that, the microbial community of snail used in the pre-feeding fermentation of municipal organic waste had influence in the physiology and rumen microbial ecology at interface with the goat, enhanced improved the organic matter degradation and feed quality, of the highly fibrous municipal organic solid waste.
CD4 and CXCR5 in Patients with Diabetic Nephropathy
Authors: Abdelhameed Sara Zaghloul , Salah Mohamed Wesam , Mohamed Okasha Kamal , Kamal Zahra Mohamed
Published: October 2021

Background: Diabetes is a metabolic condition characterized by hyperglycemia caused by defects in insulin secretion, insulin activity, or both. Diabetic nephropathy (DN) is one of the most common complications of diabetes mellitus especially type 2 diabetes. Blood CXCR5+CD4+ T cells represent three subsets: T follicular helper 1 (Tfh1), Tfh2 and Tfh17 cells. Increasing the numbers of circulating Tfh cells and also stimulation of Tfh cells have been linked with autoimmune diseases and may have a role in pathogenesis of diabetic nephropathy.

Aim of the Work: Was to investigate CD4 and CXCR5 in diabetic nephropathy patients and assess their role in the pathogenesis of diabetic nephropathy.

Subject and Methods: This study was conducted on 20 diabetic patients without nephropathy (Group I), 20 diabetic nephropathy patients (Group II) and 20 apparently healthy control subjects (Group III). Complete history taking and full clinical examination were done. Assessments of CD4 and CXCR5 were done by flowcytometry (FACS caliber, BD, CA, USA).

Results: The present study revealed a statistically significant difference between diabetic patients (Group I), diabetic nephropathy patients (Group II) and healthy control (Group III) regarding CD4+CXCR5+T follicular helper cells level. CD4+CXCR5+T follicular helper cells levels were significantly higher in diabetic nephropathy patients than in diabetic patients without nephropathy and control subjects. CD4+CXCR5+T follicular helper cells level positively correlated significantly with fasting blood glucose, postprandial blood glucose, hemoglobin A1c, creatinine, urea and urinary protein level, and negatively correlated with estimated GFR in diabetic nephropathy patients.

Conclusions: This study showed that CD4+CXCR5+T follicular helper cells level might be a useful marker for prediction and diagnosis of diabetic nephropathy patients.
Effect of Toxoplasma gondii on Some Physiological Indicators in Women's Patients with Diabetic Mellitus Type 2
Authors: Mushattat Sukayna Jabbar , Beshboosh Nawras Noori , Hassan Adhraa Baqir
Published: October 2021

Aims: Diabetes mellitus is thought to be caused by infection with the parasite Toxoplasma gondii, although this is still debated, In order to better understand the potential link between toxoplasmosis and diabetes mellitus

Study Design: China's prevalence rate of diabetes has been gradually growing in recent years, as a result of the country's rising living standards.

Place and Duration of Study: 40 patients who suffer from type 2 diabetes mellitus who were randomly chosen from the Diabetes Mellitus clinic in Al-Sadder Teaching City in Al-Najaf governorate.

Methodology: Prior research "on the link between T. gondii infection and diabetes mellitus has been conflicting, we performed matched case-control studies to see whether T. gondii seropositivity is linked" to type 2 diabetes, more research is required. To investigate T. gondii seroprevalence and recognize risk factors and potential transmital pathways of T. gondii infection in type 2 diabetes (T2DM), forty women's blood samples have been gathered and tested for anti-T. gondii IgG, IgM, and SOD. T. gondii seroprevalence in T2DM patients as a whole. Patients' information was collected through a questionnaire that included their age, weight, and blood pressure. Each patient and control participant had five milliliters of venous blood samples collected using a disposable needle and plastic syringes.

Results:  Patients ranged in age about from (35 to 65) years old. The current investigation was performed on 40 patients who suffer from type 2 diabetes mellitus, Diabetic and T. gondii patientshad a significantly higher compared with control and Diabetic patients only. Also, there were significant differences between patients of diabetic mellitus and control.

Conclusion: Blood was permitted to clot for 10 minutes at room temperature before being centrifuged at 6000 rpm for 10 minutes, after which serum was extracted and transferred into fresh disposable tubes. An ELISA test was performed on the blood samples earlier using commercially available kits (EIA-3519 IgG and IgM Germany) and SOD kits.
Localization of the ubiquitin ligase Dma1 to the fission yeast contractile ring is modulated by phosphorylation
Authors: Chen Jun‐Song , Jones Christine M. , Igarashi Maya G. , Ren Liping , Johnson Alyssa E. , Gould Kathleen L.
Published: October 2021

The timing of cytokinesis relative to other mitotic events in the fission yeastSchizosaccharomyces pombeis controlled by the septation initiation network (SIN). During a mitotic checkpoint, the SIN is inhibited by the E3 ubiquitin ligase Dma1 to prevent chromosome mis‐segregation. Dma1 dynamically localizes to spindle pole bodies (SPBs) and the contractile ring (CR) during mitosis, though its role at the CR is unknown. Here, we examined whether Dma1 phosphorylation affects its localization or function. We found that preventing Dma1 phosphorylation by substituting the six phosphosites with alanines diminished its CR localization but did not affect its mitotic checkpoint function. These studies reinforce the conclusion that Dma1 localization to the SPB is key to its role in the mitotic checkpoint.