bluuebunny/crossref_metadata_2025 huggingface dataset:
Branch Pulmonary Artery Regurgitation in Repaired Tetralogy of Fallot: Correlation with Pulmonary Artery Morphology, Distensibility, and Right Ventricular Function
Authors: Siripornpitak Suvipaporn , Lueangwattanapong Duangkanok , Sriprachyakul Apichaya , Wanitkun Suthep , Limsuwan Alisa
Published: September 2021

Background: The aim was to determine the effect of pulmonary artery (PA) morphology on the branch pulmonary artery-regurgitation fraction (BPA-RF), the relationship of pulmonary insufficiency (PI) to BPA-RF and PA-distensibility, and factors (BPA-RF and PA-distensibility) associated with right ventricular function (RVF) in repaired tetralogy of Fallot (rTOF). Methods: A total of 182 rTOF patients (median age 17.1 years) were analyzed for length, angle of PA, BPA-RF, PI, and PA-distensibility, using magnetic resonance imaging. Results: The left PA had a significant greater RF than the right PA (median (interquartile range)): LPA 43.1% (32.6–51.5) and RPA 35.2% (24.7–44.7), p < 0.001. The LPA was shorter with a narrower angle than the RPA (p < 0.001). The anatomy of the branch-PA was not a factor for the greater LPA-RF (odds ratio, 95% confidence interval: CI, p-value): length 0.44 (0.95–2.00), p = 0.28; angle 0.63 (0.13–2.99), p = 0.56. There was a strong positive correlation between PI and BPA-RF-coefficients (95% CI), p-value: LPA 0.78% (0.70–0.86), p < 0.001; RPA 0.78% (0.71–0.84), p < 0.001 and between BPA-RF and distensibility-coefficients (95%CI), p-value: LPA 0.73% (0.37–1.09), p < 0.001; RPA 1.63% (1.22–2.03), p < 0.001, respectively. The adjusted BPA-RF did not predict RVF, RPA (p = 0.434), LPA (p = 0.268). Conclusions: PA morphology is not a significant factor for the differential BPA-RF. The vascular wall in rTOF patients responds to chronic increased intravascular volume by increasing distensibility. BPA-RF is not a determinant of RVF.
Identification of Traumatic Bone Marrow Oedema: The Pearls and Pitfalls of Dual-Energy CT (DECT)
Authors: Foti Giovanni , Serra Gerardo , Iacono Venanzio , Zorzi Claudio
Published: September 2021

Dual-energy computed tomography (DECT) has been reported to successfully identify bone marrow oedema (BME) in various traumatic settings. DECT has multiple strengths, including the availability of both a 3D view of the anatomical area studied and of high-resolution dual energy specific maps super-imposed onto conventional grayscale morphological images. Windowing can be used to enhance the visualization of BME by increasing the level of the super-imposed images. Conversely, by decreasing the level of the super-imposition of color-coded images, it is possible to progressively enhance the visualization of fine anatomical details, which is useful for diagnosing associated imaging findings. Importantly, bone sclerosis may represent an important pitfall for DECT, potentially generating both false positive and false negative findings by locally altering CT numbers. The aim of this paper was to evaluate the strengths and limitations of DECT in accurately detecting traumatic BME, by considering practical approaches to imaging at several anatomical sites.
Environmentally Relevant Levels of Depleted Uranium Impacts Dermal Fibroblast Proliferation, Viability, Metabolic Activity, and Scratch Closure
Authors: Cruz Nathan , Buscaglia Robert , Salanga Matthew , Kellar Robert
Published: September 2021

Uranium (U) is a heavy metal used in military and industrial settings, with a large portion being mined from the Southwest region of the United States. Uranium has uses in energy and military weaponry, but the mining process has released U into soil and surface waters that may pose threats to human and environmental health. The majority of literature regarding U’s human health concern focuses on outcomes based on unintentional ingestion or inhalation, and limited data are available about its influence via cutaneous contact. Utilizing skin dermis cells, we evaluated U’s topical chemotoxicity. Employing soluble depleted uranium (DU) in the form of uranyl nitrate (UN), we hypothesized that in vitro exposure of UN will have cytotoxic effects on primary dermal fibroblasts by affecting cell viability and metabolic activity and, further, may delay wound healing aspects via altering cell proliferation and migration. Using environmentally relevant levels of U found in water (0.1 μM to 100 μM [UN]; 23.8–23,800 ppb [U]), we quantified cellular mitosis and migration through growth curves and in vitro scratch assays. Cells were exposed from 24 h to 144 h for a time-course evaluation of UN chemical toxicity. The effects of UN were observed at concentrations above and below the Environmental Protection Agency threshold for safe exposure limits. UN exposure resulted in a dose-dependent decrease in the viable cell count; however, it produced an increase in metabolism when corrected for the viable cells present. Furthermore, cellular proliferation, population doubling, and percent closure was hindered at levels ≥10 μM UN. Therefore, inadvertent exposure may exacerbate pre-existing skin diseases in at-risk demographics, and additionally, it may substantially interfere in cutaneous tissue repair processes.
Stability and Safety of Inhibitor Cystine Knot Peptide, GTx1-15, from the Tarantula Spider Grammostola rosea
Authors: Kimura Tadashi
Published: September 2021

Inhibitor cystine knot (ICK) peptides are knotted peptides with three intramolecular disulfide bonds that affect several types of ion channels. Some are proteolytically stable and are promising scaffolds for drug development. GTx1-15 is an ICK peptide that inhibits the voltage-dependent calcium channel Cav3.1 and the voltage-dependent sodium channels Nav1.3 and Nav1.7. As a model molecule to develop an ICK peptide drug, we investigated several important pharmaceutical characteristics of GTx1-15. The stability of GTx1-15 in rat and human blood plasma was examined, and no GTx1-15 degradation was observed in either rat or human blood plasma for 24 h in vitro. GTx1-15 in blood circulation was detected for several hours after intravenous and intramuscular administration, indicating high stability in plasma. The thermal stability of GTx1-15 as examined by high thermal incubation and protein thermal shift assays indicated that GTx1-15 possesses high heat stability. The cytotoxicity and immunogenicity of GTx1-15 were examined using the human monocytic leukemia cell line THP-1. GTx1-15 showed no cytotoxicity or immunogenicity even at high concentrations. These results indicate that GTx1-15 itself is suitable for peptide drug development and as a peptide library scaffold.
The Effects of Zearalenone on the Localization and Expression of Reproductive Hormones in the Ovaries of Weaned Gilts
Authors: Wan Boyang , Yuan Xuejun , Yang Weiren , Jiao Ning , Li Yang , Liu Faxiao , Liu Mei , Yang Zaibin , Huang Libo , Jiang Shuzhen
Published: September 2021

This study aims to investigate the effects of zearalenone (ZEA) on the localizations and expressions of follicle stimulating hormone receptor (FSHR), luteinizing hormone receptor (LHR), gonadotropin releasing hormone (GnRH) and gonadotropin releasing hormone receptor (GnRHR) in the ovaries of weaned gilts. Twenty 42-day-old weaned gilts were randomly allocated into two groups, and treated with a control diet and a ZEA-contaminated diet (ZEA 1.04 mg/kg), respectively. After 7-day adjustment, gilts were fed individually for 35 days and euthanized for blood and ovarian samples collection before morning feeding on the 36th day. Serum hormones of E2, PRG, FSH, LH and GnRH were determined using radioimmunoassay kits. The ovaries were collected for relative mRNA and protein expression, and immunohistochemical analysis of FSHR, LHR, GnRH and GnRHR. The results revealed that ZEA exposure significantly increased the final vulva area (p < 0.05), significantly elevated the serum concentrations of estradiol, follicle stimulating hormone and GnRH (p < 0.05), and markedly up-regulated the mRNA and protein expressions of FSHR, LHR, GnRH and GnRHR (p < 0.05). Besides, the results of immunohistochemistry showed that the immunoreactive substances of ovarian FSHR, LHR, GnRH and GnRHR in the gilts fed the ZEA-contaminated diet were stronger than the gilts fed the control diet. Our findings indicated that dietary ZEA (1.04 mg/kg) could cause follicular proliferation by interfering with the localization and expression of FSHR, LHR, GnRH and GnRHR, and then affect the follicular development of weaned gilts.
Prevalence of Intestinal Parasitic Infections among Children in Europe over the Last Five Years
Authors: Kantzanou Maria , Karalexi Maria A. , Vrioni Georgia , Tsakris Athanasios
Published: September 2021

While the prevalence of intestinal parasitic infections (IPI) has been most commonly studied in African and Asian populations, less is known about the prevalence rates of IPI in European children, as well as the potential risk factors that favor the spread of parasites. We aimed to review published evidence on the prevalence rates of IPI in children residing in Europe, and to quantitatively synthesize the results of published studies. We searched Medline from 1 January 2015 to 1 April 2021 to address the most recently published prevalence patterns of IPI in European children. Random-effects meta-analyses were performed by type of IPI infection, age group and sex, depending on data availability. Of the 967 potentially relevant articles, eight eligible cross-sectional studies were included in this analysis, yielding a sample of 3376 children (0–19 years). The overall prevalence rate was 5.9% for any IPI in children residing in European countries. Blastocystis hominis was the most commonly detected parasite yielding a prevalence rate of 10.7%. Other parasites included Entamoeba coli, Endolimax nana, and Blastocystis hominis. Studies focusing on specific types of parasites showed prevalence rates ranging from 1.3% for Cryptosporidium to 68.3% for Dientamoeba fragilis. Despite the scarce literature, the present review showed relatively low prevalence rates of IPI in Europe. Future studies accounting for proper diagnostic methods used for the detection of parasites and including information on potential sociodemographic factors, such as travelling history and history of immigration, are needed to guide clinicians about which children to test, as well as when and how to test children for IPI.
Genetic Diversity of Dengue Virus in Clinical Specimens from Bangkok, Thailand, during 2018–2020: Co-Circulation of All Four Serotypes with Multiple Genotypes and/or Clades
Authors: Poltep Kanaporn , Phadungsombat Juthamas , Nakayama Emi E. , Kosoltanapiwat Nathamon , Hanboonkunupakarn Borimas , Wiriyarat Witthawat , Shioda Tatsuo , Leaungwutiwong Pornsawan
Published: September 2021

Dengue is an arboviral disease highly endemic in Bangkok, Thailand. To characterize the current genetic diversity of dengue virus (DENV), we recruited patients with suspected DENV infection at the Hospital for Tropical Diseases, Bangkok, during 2018–2020. We determined complete nucleotide sequences of the DENV envelope region for 111 of 276 participant serum samples. All four DENV serotypes were detected, with the highest proportion being DENV-1. Although all DENV-1 sequences were genotype I, our DENV-1 sequences were divided into four distinct clades with different distributions in Asian countries. Two genotypes of DENV-2 were identified, Asian I and Cosmopolitan, which were further divided into two and three distinct clades, respectively. In DENV-3, in addition to the previously dominant genotype III, a cluster of 6 genotype I viruses only rarely reported in Thailand was also observed. All of the DENV-4 viruses belonged to genotype I, but they were separated into three distinct clades. These results indicated that all four serotypes of DENV with multiple genotypes and/or clades co-circulate in Bangkok. Continuous investigation of DENV is warranted to further determine the relationship between DENV within Thailand and neighboring countries in Southeast Asia and Asia.
Fatigue Crack Propagation Monitoring Using Fibre Bragg Grating Sensors
Authors: Mieloszyk Magdalena
Published: September 2021

The paper presents the analysis of the possibility of fatigue crack detection and monitoring its propagation process using fibre Bragg grating (FBG) sensors. The investigations were carried out on an aluminium alloy sample (a part of the Mi-2 helicopter rotor blade). During the fatigue test, the sample was equipped with FBG sensors applied for strain measurement and the vibration-based strain monitoring. It was observed that the strain curves determined by the FBG sensors agreed well with the fatigue force profile. However, the strain curves were almost insensitive to the crack propagation process, except in the last stage of the test, when the crack length was equal to 25 mm. The strain values and the natural frequencies of the sample that were determined experimentally were compared with the values achieved from the finite element method model, with both methods showing good agreement. Additionally, spectrogram-based analyses were performed, focused on the acoustic waves phenomena related to a crack propagation process. It was confirmed that the proposed signal processing method, based on spectrogram analyses, can be applied for the detection of fatigue crack development in metal structures.
A Gateway to Rapid Prediction of Water Quality: A Case Study in China’s South-to-North Water Diversion Project
Authors: Zhang Yuxuan , Zhao Ranhang , Wang Haofang , Peng Tao , Zhao Huaqing
Published: September 2021

Water quality assurance is the primary factor for the successful operation of water diversion projects across river basins. The rapid prediction of water pollution is the basis for timely and effective emergency control and disposal measures. In China, since the open channels intersect with numerous waterways and traffic arteries, water transfer projects are prone to sudden water pollution accidents. In this paper, the rapid prediction method was developed for sudden water pollution accidents that possibly occurred in the East Route of the South-to-North Water Diversion Project (ERP) in Shandong Province. With the empirical formula of the pollution transfer law, a rapid prediction model of water quality (WQRP) was established based on the simulation of the typical accidents in the main channel. Finally, four typical accidents were selected as application examples, and the prediction results were compared with the results from a computer numerical simulation to demonstrate the validity of the model. The results showed that the prediction results by the WQRP model meet the accuracy requirements. This method is of great significance for providing water transport security in the extreme conditions of long-distance water transfer projects.
Geochemical and Isotope Characterisation of Thermo-Mineral Springs of Corsica Island: From Geological Complexity to Groundwater Singularity
Authors: Dupuy Margaux , Garel Emilie , Huneau Frederic , Santoni Sebastien , Di Rosa Maria , Mattei Alexandra
Published: September 2021

Understanding hydrogeological processes at the origin of thermal and mineral groundwater are necessary to ensure their sustainable management. However, many processes are involved in their genesis and often only one or two processes are investigated at the same time. Here, we propose to use an innovative combination of geochemical, isotopic (34S, 14C, 18O, 2H) and geothermometry tools to identify, for the first time in a multi-composite geological context, all processes at the origin of diversified thermo-mineral waters. 19 springs covering a wide range of temperature and chemical composition emerging on a restricted area of Corsica Island (France) were selected. Geochemical results highlight five geochemical provinces, suggesting a common origin for some of them. Geothermometry tools show the unexpected involvement of a common deep groundwater reservoir within this non-active zone. Water stable isotopes highlight a contrasted altitude in recharge areas supplying lowland springs. This suggests that different flow patterns have to be involved to explain the wide geochemical diversity observed and to allow the design of a very first conceptual groundwater-flow model. This paper demonstrates the efficiency of the combination of the selected tools as tracers of water–rock interaction, independently of flow depth, intrinsic water properties, geological conditions and interaction time disparities.
Dual Benefit of Rainwater Harvesting—High Temporal-Resolution Stochastic Modelling
Authors: Snir Ofer , Friedler Eran
Published: September 2021

The objective of the presented study was to develop a high-temporal-resolution stochastic rainwater harvesting (RWH) model for assessing the dual benefits of RWH: potable water savings and runoff reduction. Model inputs of rainfall and water demand are used in a stochastic manner, maintaining their natural pattern, while generating realistic noise and temporal variability. The dynamic model solves a mass-balance equation for the rainwater tank, while logging all inflows and outflows from it for post-simulation analysis. The developed model can simulate various building sizes, roof areas, rainwater tank volumes, controlled release policies, and time periods, providing a platform for assessing short- and long-term benefits. Standard passive rainwater harvesting operation and real-time control policies (controlled release) are demonstrated for a 40-apartment building with rainfall data typical for a Mediterranean climate, showing the system’s ability to supply water for non-potable uses, while reducing runoff volumes and flows, with the latter significantly improved when water is intentionally released from the tank prior to an expected overflow. The model could be used to further investigate the effects of rainwater harvesting on the urban water cycle, by coupling it with an urban drainage model and simulating the operation of a distributed network of micro-reservoirs that supply water and mitigate floods.
Urban Pluvial Flood Management Part 1: Implementing an AHP-TOPSIS Multi-Criteria Decision Analysis Method for Stakeholder Integration in Urban Climate and Stormwater Adaptation
Authors: Axelsson Charles , Giove Silvio , Soriani Stefano
Published: September 2021

Cities are facing increasing pressures to enact adaptation measures due to climate change. While blue-green infrastructure has emerged as a focal adaptation technique for stormwater management, in order to craft adaptation policies cities must consider a multitude of emerging, complex, and competing stakeholder interests around multiple adaptation alternatives. However, accounting for these different interests, analyzing their diverse priorities, and maintaining a transparent decision-making process is not easily achieved within the existing policy frameworks. Here we define and present a combined multi-criteria decision analysis (MCDA) of the analytic hierarchy process (AHP) and the technique for order of preference by similarity to ideal solution (TOPSIS) methods that easily integrates and quantifies stakeholder priorities while remaining accessible for non-experts engaged in the policy-making process. We demonstrate the method’s effectiveness through analyzing opinions about stormwater adaptation in New York City across several stakeholder groups. The method succeeds in integrating quantitative and qualitative judgements, indicating stakeholder preferential differences and allowing for more inclusive policy to be crafted. It can be extended beyond stormwater to many urban climate adaptation decisions facing multi-criteria considerations.
Research on Desktop Wide Range Wireless Power Transfer Based on High Frequency Electric Field
Authors: Chen Xiyou , Wang Zhe , Lang Zhengying , Li Tao , Qi Chen
Published: September 2021

This paper proposes a desktop wireless power transfer system that can wirelessly supply power to electrical equipment in a certain space above the aluminum foil using only a high-frequency electric field. Compared with other wireless power supply systems, this system has a smaller power receiving device and a wider power supply range, which is convenient for wireless power supply of portable electrical equipment and low-power electric vehicles. The power receiving device of the system is only the size of a mobile phone, and the power supply range can reach 1.2 m2. This article introduces the system design, electromagnetic field simulation and experiment of the desktop wireless power transfer system. The experimental results show that by using a mobile phone-sized receiving device to connect a light bulb and a fan, multiple loads can simultaneously receive power in a specific space above the desktop power supply. In addition, people can hold the power receiving device for wireless charging.
О совершенствовании модели государственного управления в сфере науки, технологий и инноваций
Authors:   Институт проблем развития науки РАН, Остапюк Сергей Федорович , Фетисов Вячеслав Петрович ,   Институт проблем развития науки РАН
Published: September 2021

В статье рассмотрены основные изменения систем управления в сфере науки, технологий и инноваций, задачи, функции и полномочия субъектов управления в связи с принятием новой редакции Конституции Российской Федерации, Федерального конституционного закона «О Правительстве Российской Федерации», указов Президента Российской Федерации и ряда иных правовых актов. Предложено создать в структуре Правительства РФ вневедомственный федеральный орган исполнительной власти, основной задачей которого будет организация и координация внедрения достижений науки и технологий в реальный сектор производства. Сформулированы задачи, функции и полномочия такого органа управления.
Влияние таможенных платежей как института развития на стимулирование экономического роста
Authors:   Институт экономики РАН, Лебедев Никита Андреевич
Published: September 2021

В статье кратко проанализировано влияние таможенных платежей на отдельные параметры финансирования расходов федерального бюджета, направленного на реализацию ключевых приоритетов и национальных целей, что будет способствовать ускорению экономического роста. Показано, что таможенные поступления в федеральный бюджет выступают важной характеристикой, позволяют своей частью удовлетворять общественные потребности, оставаясь одним из стабильных источников формирования его доходов. Сделан вывод о необходимости внесения в контрольные показатели реализации Стратегии развития таможенной службы РФ до 2030 г. показателей таможенных платежей, способствующих финансированию программ расходной части бюджета, влияющих на стимулирование экономического роста.
Управление изменениями в Федеральном проекте "Региональная местная дорожная сеть" в составе Национального проекта "Безопасные качественные дороги" на основе моделей преобразований 4P "Ориентация на результаты", "трансформационный треугольник" и 4R Гуияра-Кейли
Authors:   Московский государственный университет пищевых производств, Филатов Владимир Владимирович , Безпалов Валерий Васильевич ,   Российский экономический университет им. Г.В. Плеханова, Крыгина Ирина Евгеньевна ,   Московский автомобильно-дорожный государственный технический университет, Горина Татьяна Владимировна ,   МИРЭА - Российский технологический университет, Сафронов Александр Сергеевич ,   Московский городской университет управления Правительства Москвы им. Ю.М. Лужкова
Published: September 2021

В данной статье рассмотрен вопрос управления изменениями в Федеральном проекте «Региональная и местная дорожная сеть» в составе Национального проекта «Безопасные качественные дороги» на основе моделей преобразований 4Р, «трансформационный треугольник» и 4R Гуияра-Кейли. Установлено, что инвестиционный потенциал Федерального проекта значительный и, используя смешанные инвестиции заинтересованного среднего и крупного бизнеса, а также государственные средства, транспортная отрасль на данном этапе в основном решила основную инвестиционную задачу на федеральном и региональном уровнях - восстановления и модернизации транспортного комплекса в 83 субъектах РФ и 104 городских агломерациях.
Модели и сценарии развития социально-экономических систем
Authors:   Санкт-Петербургский государственный экономический университет, Юденко Марина Николаевна
Published: September 2021

В статье определена цель исследования, заключающаяся в необходимости проведения анализа существующих и прогнозируемых моделей и сценариев развития российских социально-экономических систем. Анализ осуществлен исходя из понимания социально-экономической системы как частичного образа реальности в индивидуальном или общественном сознании. Приведено краткое описание существующих социально-экономических моделей в России и стратегий их развития. Сделан вывод о важности выбора методов описания моделей развития социально-экономических систем. Выявлены цели и недостатки предлагаемых методов описания модели развития социально-экономических систем.
Оценка конъюнктуры рынка и развития сервисизации мезо-экономического уровня
Authors:   Российская государственная академия интеллектуальной собственности, Шаматов Индус Кашипович , Жуковская Ирина Викторовна ,   Казанский национальный исследовательский технологический университет, Морозов Александр Викторович ,   Казанский национальный исследовательский технологический университет
Published: September 2021

В научной статье исследованы терминологические понятия сервисизации, услуги и рынка услуг в рамках классической и современной научных школ. Классифицированы различные виды услуг и выявлены ключевые факторы, способствующие развитию сервисизации и конъюнктуры рынка. Структурирован конкурентный рынок услуг на примере Республики Татарстан.
Практическое применение результатов космической деятельности в транспорте
Authors:   Российский университет дружбы народов, Варанкин Василий Сергеевич , Муртузалиева Светлана Юрьевна ,   Российский университет дружбы народов, Самб Рокхая ,   Российский университет дружбы народов
Published: September 2021

Выход нашей страны в космос в двадцатом веке имел огромное политическое и экономическое значение. В настоящее время космос остается приоритетным и важным направлением в экономике и политике государств. Применение космических технологий представляет собой огромный бизнес многоотраслевого характера, имеющий колоссальный потенциал в росте доходов страны. В статье анализируется применение космических технологий в транспортной инфраструктуре, рассматривается зарубежный и российский опыт.
Противодействие манипулированию рынком в системе обеспечения экономической безопасности фондового рынка
Authors:   Главное управление криминалистики Следственного комитета Российской Федерации, Опальский Александр Павлович ,   Мурманский филиал РАНХиГС
Published: September 2021

В системе обеспечения экономической безопасности фондового рынка участвуют представители различных объектов экономики страны. В первую очередь, это органы контроля бирж – организаторов торгов, на которых выявляются сомнительные сделки. Специалисты Департамента противодействия недобросовестным практикам Центрального банка Российской Федерации осуществляют проверки выявленных нарушений и принимают решение о привлечении виновника к административной ответственности либо передаче материалов проверки в правоохранительные органы по подследственности. Среди недобросовестных практик наиболее часто встречается такое спекулятивное явление как манипулирование рынком, общественная опасность которого состоит в причинении существенного вреда интересам граждан и юридических лиц, общества и экономики в целом, подрывая доверие инвесторов и участников торговли к организованным финансовым и товарным рынкам, ухудшая условия для инвестирования и торговли на них, препятствуя их эффективному развитию и укреплению международной конкурентоспособности.
Safety Events Impacting Hospitalized Patients Following Motor Vehicle Crashes: A Qualitative Study of Reports From Pennsylvania Hospitals
Authors: Kukielka Elizabeth
Published: September 2021

Motor vehicle crashes (MVCs) are a significant cause of morbidity and mortality in the
United States and around the world. When a patient who has experienced trauma in an
MVC presents to the emergency department, they may be unable to participate in their
own care due to numerous factors, such as being unconscious, physically incapacitated, or suffering from confusion. To better characterize challenges with care of these patients, we analyzed reports of patient safety events submitted to the Pennsylvania Patient Safety Reporting System (PA-PSRS) related to MVCs, and we identified 282 reports for analysis that occurred from 2018–2020. Patients were more often male (58.9%; 166 of 282) than female (41.1%; 116 of 282), and they ranged in age from 1 to 93 years. A total of 13.1% (37 of 282) of reports were classified as serious events (i.e., events that resulted in patient harm), compared with 2.9% in the full acute care PA-PSRS database. Problems with monitoring or treatment were most common (43.3%; 122 of 282), followed by problems with evaluation (18.4%; 52 of 282), falls (11.7%; 33 of 282), problems with documentation (7.4%; 21 of 282), medication errors (7.4%; 21 of 282), and problems with transfers (6.4%; 18 of 282). Some potential contributing factors included communication breakdowns, lack of policies or protocols or unawareness about existing policies or protocols for treating certain patient populations, and prioritization of conditions related to an MVC over underlying health conditions.
CATalyst for Change: How Members of WellSpan’s Central Alert Team (CAT) Are Revolutionizing Sepsis Care
Authors: Allen Caitlyn
Published: September 2021

In the United States, almost 1 million patients with sepsis are admitted to hospitals annually, and the cost of managing sepsis admissions is higher than any other disease state.1 Early identification and treatment are critical for survival, though both are notoriously difficult as symptoms are often nonspecific.

Four years ago, WellSpan Health asked, “What if there were a way to provide real-time, meaningful clinical decision support to bedside providers to identify sepsis sooner and start lifesaving treatment?” Meet Margaret D’Ercole, Patricia Everett, Dana Gaultney, Angela Mays, Brenna Simcoe, and Cynthia Yascavage, who share how their Central Alert Team decreased mortality rates, increased bundle compliance, and proved there is a better way.
Analysis and Forecasting Dynamics of Digital Transformation of Economy of the Russian Federation (on the Example of the Measurement of the Organization’s Digital Performance)
Authors: Prokhorov P. E. , Minashkin V. G.
Published: September 2021

The introduction of digital technologies in the monitoring and management activities of organizations is an important tool for the transformation of economic system at modern phase of the latest industrial and technological revolution. Currently, there is no unifed methodological apparatus for describing the state and development prospects of digital transformation. The analysis of objective patterns of the digital transformation of the Russian economy can be carried out by constructing mathematical and statistical models that make it possible to analyze the stages of digital maturity in the past and to determine the future development of projected digital phenomena.

The purpose of this article lies in modelling and forecasting of dynamics of digital transformation of the activities of organizations.

Digital transformation was measured based on indicators of the use of information and communication technologies in organizations, namely: Internet connection, website, purchase of goods and services via the Internet, use of software tools of the ERP, CRM, SCM class.

Growth curves are one of the most common tools for modeling technological development trends. For each time series, the accuracy of four models of growth curves was assessed: the Gompertz, Weibull's, logistic and log-logistic.

The practical application of this study is that the proposed approach can be used to assess trends in ICT diﬀusion in organizations by type of economic activity and by size to obtain a more complete characterization of digital maturity and further prospects for digital transformation of the Russian economy.
Il Concilio di Trento (1545 - 1563)
Authors: Tolić Željko
Published: September 2021

Secondo la numerazione cattolica è il XIX concilio ecumenico. Richiesto da decenni da più parti, e con sempre maggiore urgenza, il concilio non poté svolgersi per molto tempo. Infine, dopo tre inutili convocazioni, Paolo III con la bolla Laetare Jerusalem (1544) indisse l'assemblea per il 15 marzo 1545 a Trento, indicando compiti principali. Il concilio però si aprì solo 13 dicembre 1545 in presenza 31 vescovi, in maggioranza italiani. Durante il primo periodo, che comprese le sessioni
I-X, quando fu deciso di trattare parallelamente le questioni dogmatiche e quelle della riforma ecclesiastica, furono approvati importanti definizioni e decreti, tra gli altri quelli sulla Santa Scrittura, il peccato originale, la giustificazione e altre cose. Nell'VIII sessione (11 marzo 1547) i partecipanti decisero di trasferire
il concilio a Bologna. Dopo la morte di Paolo III fu eletto papa con nome di Giulio III il cardinale Del Monte, fino allora presidente del concilio. Sotto il suo pontificato ebbe luogo il secondo periodo del concilio (dal 1551 al 1552), che comprendeva le sessioni XI-XVI. In questo periodo al concilio vennero i delegati protestanti della Germania, ma si tornarono presto in patria, senza essere riusciti a imporre le loro richieste. Circostanze politiche condussero alla sospensione del concilio (1552). Ma ne novembre 1560 il nuovo papa, Pio IV, ordinò il proseguimento dei lavori conciliari: è il terzo periodo del concilio di Trento, dal 1562 al 1563, che comprese le sessioni XVII-XXV. I principi protestanti radunati a Naumburg decisero di non accogliere l'invito. Nelle sessioni si approvarono decreti sull'obbligo della residenza dei vescovi, il carattere sacrificale della santa messa,
la consacrazione sacerdotale, il matrimonio, il purgatorio, la venerazione dei santi e delle reliquie, l'indulgenza, i seminari. Con la
bolla Benedictus Deus et Pater (il 26 gennaio 1564) Pio IV confermava l'opera del concilio.
„Psallite sapienter“ (Ps 47, 8b). Teološka razmatranja Josepha Ratzingera o glazbenoj umjetnosti u liturgiji
Authors: Diklić Bruno , Vulić Boris
Published: September 2021

Članak tematizira teološka promišljanja Josepha Ratzingera o glazbi u kontekstu liturgije Katoličke Crkve. Uvodno se kratko opisuju krize i izazovi te novija teološka učenja koja crkvenu glazbu u postkoncilsko doba dovode do stanja kulturološke shizofrenije i teoloških lutanja. Središnji dio članka posvećen je Ratzingerovoj teološkoj interpretaciji crkvene glazbe čija je posebnost otkrivanje i promišljanje biblijskih uporišta o glazbi u liturgiji. U tom se kontekstu nalaze i odgovori na izazove i krize koje su snašle crkvenu glazbu, ali se i jasno otkrivaju temeljna biblijsko-teološka načela koja određuju istinsku narav i ulogu glazbe u kršćanskom kultu. Zaključno se donose neka načela i putokazi za
crkvenu glazbu danas.
Ascending Colon Duplication-A Case Report with Review of Literature
Authors: Painuly Guru Prasad , Tyagi Col. Ashok , Kaushal Rashk , Singhal Mini
Published: September 2021

Gastro – intestinal duplications are usually detected in children before 2 years of age due symptoms/complications associated with the condition or during surgery in the child for some unrelated condition. In adults colonic duplication is of rare occurrence and often diagnosed during surgery. However, it may be diagnosed pre operatively due to symptoms of obstruction, volvulus or rarely due to perforation. We present an adult having tubular duplication of ascending colon, that presented with perforation. The duplication had a blind end and did not have distal communication. In addition, it had its own blood supply. The management of the case is discussed. Aetiogenesis of the anomaly is enumerated and literature reviewed.
For ascending colon duplication similar meaning word accessory ascending colon has also been used in the manuscript.
Air quality in Finland according to air quality measurements and satellite observations
Authors:   Finnish Meteorological Institute, Komppula Birgitta , Karppinen Tomi , Virta Henrik , Sundström Anu-Maija , Ialongo Iolanda , Korpi Kaisa , Anttila Pia , Salmi Jatta , Tamminen Johanna , Lovén Katja
Published: September 2021

In this report the current air quality in Finland has been assessed with air quality measurement data and satellite observations. The assessment of ambient air concentrations included following air impurities: NO2, NOx, PM10, PM2,5, SO2, CO, O3, benzo(a)pyrene, benzene, Pb, As, Cd ja Ni. For these pollutants air quality assessment thresholds are given in air quality legislation (2008/50/EY, 2004/107/EY). Assessment has been performed for air quality zones. The main data set included air quality measurements performed in Finland during 2015–2019. Satellite observations were used as an objective assessment tool in analysis of the spatial variation of NO2 and CO concentrations. Air quality measurements show that air quality has improved in Finland in many respects. Especially the need to monitor NO2 and PM10 with continuous measurements has decreased. Growing understanding of national benzo(a)pyrene concentrations has increased the monitoring needs. Efforts to decrease ozone levels still requires international actions. SO2, CO, benzene and heavy metal concentrations are on a low level in Finland outside industrial areas and other assessment methods than continuous monitoring can be used, and the number of continuous monitoring sites has already decreased. Satellite-based concentrations of nitrogen dioxide and carbon monoxide as well as their spatial variation in Finland were analyzed using observations from the TROPOsperic Monitoring Instrument (TROPOMI). The analysis of CO over Finland was carried out for the first time in this project. Results show that overall annual CO concentrations over Finland are low and spatial variability is small. Also, NO2 concentrations over Finland are rather low, but spatial patterns are more clearly visible. The highest NO2 concentrations are observed over the largest cities. By establishing a relationship between ground-based and satellite total column concentrations, surface concentrations of NO2 and CO were estimated from the satellite data for the zones. The satellite-based estimate for annual NO2 surface concentration over Helsinki metropolitan area is 28 μg/m3, and for the rest of Finland mostly between 10–15 μg/m3. For CO the differences between monitoring areas are small, with estimates varying between 160–164 μg/m3 or in other words about 0,16 mg/m3.
Estrategias cognitivas y nivel de comprensión de textos académicos en estudiantes ingresantes en la universidad – Perú
Authors: Mamani-Apaza William , Mamani-Guevara Henry , Vilca Fredy , Vilca-Apaza Henry-Mark , Carpio Darssy , Layme-Huamaní Jaime
Published: September 2021

The purpose of contemporary university education is to strengthen the capacities of understanding academic texts of future professionals as autonomous agents who manage their learning. Within this framework, the article aimed to determine the degree of relationship between cognitive strategies and the compression of academic texts in Peruvian university students, in order to have a cognitive profile of those entering the university. The study population consisted of 172 first cycle students. The methodology used was descriptive - correlational cross-sectional. It was concluded, due to the correlation coefficient of Spearman's Rho equal to 0.7929 and the estimated P-value of 0.001 lower than the significance level (0.05), that there is a high positive correlation between cognitive strategies and comprehension of the students' academic texts, although this relationship is not decisive.
Peran Perempuan Karir Membangun Komunikasi Positif Interpersonal dalam Keluarga Multikultural
Authors: Tri Darmaningrum Khaerunnisa , Hidayatullah Ahmad
Published: September 2021

Penelitian ini berupaya untuk mengungkap tentang peran perempuan dalam membangun komunikasi positif interpersonal di dalam keluarganya yg multikultural. Salah satu peran perempuan dalam keluarga adalah membangun komunikasi positif interpersonal di dalam keluarganya. Komunikasi yang diharapkan terjadi dalam keluarga sebaiknya bersifat interpersonal. Dimana dalam pola komunikasi interpersonal ada ketergantungan dari masing-masing individu untuk saling bertatap muka satu sama lainnya. Akan tetapi sikap acuh menjadi masalah utama komunikasi dalam keluarga multikultur. Metode kualitatif deskriptif fenomenenologi dalam penelitian ini digunakan untuk mengungkap aspek sosial psikologis yang dialami perempuan ketika dia memiliki peran sebagai pembangun komunikasi aktif interpersonal dalam keluarganya. Penelitian ini dilakukan pada narasumber perempuan bekerja yang memiliki keluarga besar berasal dari beraneka ras. Selain itu peneliti juga melakukan studi pustaka mengenai teori komunikasi interpersonal yang bisa diterapkan dalam keluarga multikultural dan teori psikologi perempuan. Dalam penelitian ini ditemukan bahwa peran perempuan dalam membangun komunikasi aktif di dalam keluarganya adalah sangat penting.
INTERNALISASI NILAI-NILAI PANCASILA DALAM MENINGKATKAN KESADARAN BELA NEGARA PADA GENERASI MILENIAL
Authors: Azzaria Shabika
Published: September 2021

At this moment the Indonesian people has experienced many changes expected to the globalization change. With the varying developments in this stage of globalization, it suggests a trying for the Indonesian people to go on to appropriate up and adhere to the flow of innovation. In the present cycle of globalization, the position of Pancasila is absolutely highly remarkable in conduct to preserve the survival of the identity of the Indonesian societies, because the affect of globalization of borders between states seems invisible, so that various foreign cultures easily penetrate into community. The fundamental issue in this investigation is to internalize the values of Pancasila in developing consciousness of safeguarding the state in the millennial generation and struggles to internalize the values of Pancasila in enhancing awareness of fighting for the country in the millennial ages. In this view, the researcher used interview as data collection method, and backed by literature review on secondary documents. The results study, the relevance of internalizing the values of Pancasila because Pancasila has a serve and position in the nation and state and can develop appreciation of safeguarding the state by practicing Pancasila values in workaday life in order to keep the existence of the nation and state of Indonesia and reinforce awareness of maintaining the state, specifically the millennial generation. The development of state defense information is given lines to overcome understandings, ideologies, and cultures that are opposed to the identity values maintained by the Indonesian nation. The state defense is brought out on going support through education, training and socialization so that it can support the authority for the opportunity of defense systems.
Infrastructure Vandalism and Protection in a Vulnerable Zimbabwean Environment: Review of the Structural Materialism Theory
Authors:   Lecturer, Zimbabwe Open University Faculty of Applied Social Sciences & Faculty of Commerce and Law, Zimbabwe., Chingozha Misheck , Zvokuomba Kwashirai ,   Research Associate, Department of sociology, University of Johannesburg, Zimbabwe.
Published: September 2021

Many institutions are facing or have faced challenges related to vandalism of equipment and property in Zimbabwe. This criminal phenomenon is not only restricted and peculiar to this country but is experienced in other regions of the world, however with variations. The purpose of the study is to explore and unpack the various dimensions of infrastructure vandalism by gazing at Zimbabwe Electricity Supply Authority (ZESA) a power utility in Zimbabwe. The level of vandalism has been increasing unabated resulting in in a multitude of undesirable effects on the power utility and the economy as a whole. A plethora of stimulants have been seen to be triggering and sustaining the theft and vandalism of the infrastructure which targets copper conductors, copper windings, oils and the poles in the majority of cases. The study adopted the mixed method approach due to its technical advantage of converging and merging qualitative and quantitative data in order to provide comprehensive results and produce new knowledge claims. This methodological framework was guided by the structural materialism theory which is an off shot of the critical criminology perspective. Thus, the study found out that infrastructure vandalism is representative of a broader dysfunctional socioeconomic system of a country riddled by poverty, unemployment and the absence of mores and values within communities. Consequently, the levels of infrastructure vandalism have spiraled to unprecedented levels. The study concludes that the government is failing to sufficiently address the macro-economic fundamentals as way of discouraging citizens from engaging in crime and criminality while the traditional leaders are not being respected yet they have a significant role they can play in promoting the stability and serenity of communities. In view of these conclusions the study recommends that all stakeholders contribute towards the protection of all infrastructure and migrate to digitalize the protection of such infrastructure as well as promulgation of appropriate pieces of legislation.
Energy Efficient and VM Consolidation Framework using Improved Spider Monkey Optimization Algorithm
Authors:   Research Scholar, ACE Engineering College, Department of Computer Science & Engineering, Hyderabad, India., Kumar Kethavath Prem , Ragunathan Thirumalaisamy ,   Ph.D, SRM University, Department of Computer Science & Engineering, Amaravathi, India., Vasumathi Devara ,   Ph.D, Jawaharlal Nehru Technological University, Department of Computer Science & Engineering, Hyderabad, India.
Published: September 2021

Cloud Computing is rapidly being utilized to operate informational technological services by outstanding technologies for a variety of benefits, including dynamically improved resources planning and a new service delivery method. The Cloud computing process is occurred by allowing the client devices for data access through the internet from a remote server, computers, and the databases. An internet connection is linked among the front end users such as client device, network, browser, and software application with the back end that constitutes of servers, computers, and database. For satisfying the demands of the Service Level Agreement (SLA), providers of cloud service should reduce the usage of energy. Capacity reservations oriented system is available by clouds’ providers to permit users for customizing Virtual Machines (VMs) having specified age and geographic resources, reduces the amount to be paid for cloud services. To overcome the aforementioned issue, an Improved Spider Monkey Optimization (ISMO) approach is proposed for cloud center optimization. The VM consolidation architecture based on the proposed ISMO algorithm decreases energy usage while attempting to prevent Service Level Agreement breaches. The accessibility of hosts or virtual machines (VMs) for task performance is measured by fitness. If the number of tasks to be handled increases the hosts of VMs available at right state. The proposed VM consolidation architecture decreases energy usage while also attempting to prevent Service Level Agreement breaches and also provide energy-efficient computing in data centers. The proposed approach may be utilized to provide energy-efficient computing in data centers. The energy efficiency of the proposed ISMO method is achieved 28266 whereas, the existing algorithm showed an energy efficiency of 6009 and 10001.
Revertiamo a rivertire o adottiamo revertare?
Authors: Thornton Anna M.
Published: September 2021

Diversi lettori chiedono informazioni su quale sia la forma italiana corrispondete al verbo inglese to revert, che ha usi tecnici in biologia e in informatica. I lettori citano revertire per l’uso in biologia, e revertare per l’uso in informatica, ma dichiarano di non aver trovato questi verbi nei dizionari.