bluuebunny/crossref_metadata_2025 huggingface dataset:
Veedurías ciudadanas bajo una perspectiva de valor público. Retos de las veedurías en Pichincha (Ecuador)
Authors: Torres Obando Cristian , Jara-Iñiguez Irma
Published: December 2021

Las veedurías ciudadanas constituyen el mecanismo de control social institucionalizado más utilizado a nivel general en Ecuador y, por ello, se presenta este estudio desde una perspectiva ciudadana y su interacción con el Estado. Se analizan las experiencias de las personas que ejercieron este derecho calificándose como veedores en el Consejo de Participación Ciudadana y Control Social en la Provincia de Pichincha durante los períodos 2016 – 2017. Se abordaron los servicios provistos, los resultados, la confianza generada y expectativas alcanzadas. Con estos aspectos y sobre la base de la institucionalidad vigente se discute la generación de valor público desde este mecanismo. Para el efecto, a partir de un diseño de estudio de casos se aplicaron 25 encuestas a veedores ciudadanos, cinco entrevistas semiestructuradas a coordinadores de las veedurías, se revisaron 11 resoluciones del pleno del Consejo respecto a los procesos realizados y 11 informes finales presentados por los veedores ante el mismo organismo. Como resultado se identificó que, si bien existen limitantes al ejercicio institucionalizado, no obstante, este mecanismo cuando asegura la participación y colaboración activa de los ciudadanos puede generar valor público.
contrato de seguro en el Ecuador – conceptos básicos y análisis de la reticencia, falsa declaración y acuerdos transaccionales
Authors: Carrión Márquez Carlos Alberto
Published: December 2021

El contrato de seguro, conocido como un contrato oneroso-aleatorio y de adhesión, constituye una práctica mercantil común que no deja de ser ajena en cuanto a sus formalidades técnicas y jurídicas, bajo las cuales se desarrollan y poseen un elemento distintivo, otorgar una cobertura e indemnizar, dentro de los límites convenidos, si ocurre el siniestro señalado en el contrato. Sin embargo, las compañías de seguros pueden invocar hechos o circunstancias excluyentes de su responsabilidad al momento de indemnizar, ya sea por reticencia, falsa declaración o acuerdos transaccionales efectuados por los asegurados. En este contexto, los asegurados, sea por una conducta culposa o de forma deliberada, incurren en acciones que entorpecen el cumplimiento del contrato de seguro, que dan como resultado una afectación a los derechos de las aseguradoras. Finalmente, los resultados obtenidos de esta reflexión buscan abordar, de forma integral, como la reticencia, falsa declaración o los acuerdos transaccionales por parte del asegurado violentan las estipulaciones contractuales y como se ve afectado el riesgo asegurable cuando ocurre el siniestro bajo cobertura contractual.
О вакансионной природе высокотемпературного фона внутреннего трения в твердых телах
Authors: Гриднев С.А. , Калинин Ю.Е.
Published: December 2021

High-temperature internal friction in an amorphous CuTi alloy is investigated. Exponential regions with different activation energies are observed on the dependence of internal friction on temperature on both sides of the glass transition temperature. An exponential increase in the background of internal friction with temperature in both sites is associated with the migration of vacancy-like defects in the amorphous structure under the influence of mechanical stresses, while frozen defects of constant concentration migrate to the glass transition temperature. After the transition to a state of thermodynamic equilibrium , the concentration the number of migrating defects increases exponentially. Based on the experimental results of measuring the high-temperature background, estimates of the activation energy of migration and the formation of vacancies of similar defects in the amorphous structure of the alloy under study are made.
Data Collection Mechanisms in Health and Wellness Apps: Review and Analysis
Authors: Philip Ben Joseph , Abdelrazek Mohamed , Bonti Alessio , Barnett Scott , Grundy John
Published: December 2021

Background

There has been a steady rise in the availability of health wearables and built-in smartphone sensors that can be used to collect health data reliably and conveniently from end users. Given the feature overlaps and user tendency to use several apps, these are important factors impacting user experience. However, there is limited work on analyzing the data collection aspect of mobile health (mHealth) apps.

Objective

This study aims to analyze what data mHealth apps across different categories usually collect from end users and how these data are collected. This information is important to guide the development of a common data model from current widely adopted apps. This will also inform what built-in sensors and wearables, a comprehensive mHealth platform should support.

Methods

In our empirical investigation of mHealth apps, we identified app categories listed in a curated mHealth app library, which was then used to explore the Google Play Store for health and medical apps that were then filtered using our selection criteria. We downloaded these apps from a mirror site hosting Android apps and analyzed them using a script that we developed around the popular AndroGuard tool. We analyzed the use of Bluetooth peripherals and built-in sensors to understand how a given app collects health data.

Results

We retrieved 3251 apps meeting our criteria, and our analysis showed that 10.74% (349/3251) of these apps requested Bluetooth access. We found that 50.9% (259/509) of the Bluetooth service universally unique identifiers to be known in these apps, with the remainder being vendor specific. The most common health-related Bluetooth Low Energy services using known universally unique identifiers were Heart Rate, Glucose, and Body Composition. App permissions showed the most used device module or sensor to be the camera (669/3251, 20.57%), closely followed by location (598/3251, 18.39%), with the highest occurrence in the staying healthy app category.

Conclusions

We found that not many health apps used built-in sensors or peripherals for collecting health data. The small number of the apps using Bluetooth, with an even smaller number of apps using standard Bluetooth Low Energy services, indicates a wider use of proprietary algorithms and custom services, which restrict the device use. The use of standard profiles could open this ecosystem further and could provide end users more options for apps. The relatively small proportion of apps using built-in sensors along with a high reliance on manual data entry suggests the need for more research into using sensors for data collection in health and fitness apps, which may be more desirable and improve end user experience.
Можливості магнітно-резонансної томографії у ранній діагностиці прогресування м’язових дистрофій
Authors: Palahuta H.V.
Published: December 2021

Прогресуючі м’язові дистрофії — це генетично гетерогенна група порушень, які характеризуються прогресуючою м’язовою слабкістю, атрофією м’язів і руховими порушеннями. Це рідкісна група патологій, що являє собою діагностичну проблему в практиці лікаря-невролога. Комбінація клінічних, рентгенологічних і лабораторних методів обстеження відіграє велику роль при постановці правильного діагнозу. Магнітно-резонансна томографія (МРТ) м’язів використовується для діагностики первинного ураження м’язів, ґрунтуючись на специфічних патернах ураження м’язів. У статті ми коротко обговоримо можливості ранньої діагностики м’язових дистрофій і відзначимо роль МРТ м’язів як високоінформативного діагностичного методу при прогресуючих захворюваннях м’язів.
Analisis Deskriptif Potensi Pariwisata di Desa Sekitar Kawasan Ekonomi Khusus (KEK) Likupang
Authors: Firmansyah Ade
Published: December 2021

Perkembangan pariwisata Provinsi Sulawesi Utara dalam lima tahun terakhir telah mengalami peningkatan yang signifikan. Kabupaten Minahasa Utara, salah satu wilayah administratif, telah ditetapkan sebagai Zona Ekonomi Khusus, tepatnya di wilayah Likupang Timur oleh pemerintah pusat pada akhir tahun 2019. Penelitian ini bertujuan untuk menganalisis dan menggambarkan potensi sumber daya pariwisata di sekitar Likupang Zona Ekonomi Khusus (KEK Likupang). Fokus analisis adalah Tujuan, Fasilitas, dan Aksesibilitas. Dengan menggunakan analisis kualitatif deskriptif, observasi, dan wawancara untuk pengambilan data. Hasil penelitian menunjukkan bahwa beberapa destinasi menarik bagi wisatawan asing dan lokal di Sulawesi Utara karena Destinasi menawarkan pantai yang indah dengan fasilitas dan kemudahan aksesibilitas. Daerah ini juga sangat potensial sebagai pedalaman dan untuk mendukung KEK. Namun, masih ada banyak kendala bagi masyarakat untuk mengembangkan sumber daya yang ada karena terbatasnya kapasitas sumber daya manusia.
ВЫСОКОЧАСТОТНЫЕ И СВЕРХВЫСОКОЧАСТОТНЫЕ ПРОВОЛОЧНЫЕ ЧИП-ИНДУКТИВНОСТИ ТИПОВ КИК, КИК1 И КИФ: ПАРАМЕТРЫ И ПРИМЕНЕНИЕ
Authors: Белков И. , Еремеев Ю. , Малышев И.
Published: December 2021

АО «НПО «ЭРКОН» — известный российский разработчик и производитель пассивных электронных компонентов. В статье описаны ключевые параметры проволочных ВЧ- и СВЧ-чип-индуктивностей производства компании, их типовые области применения, представлены примеры моделирования в САПР с использованием предоставляемых моделей чип-индуктивностей.
АРХИТЕКТУРА И ОБЛАСТИ ПРИМЕНЕНИЯ ПЛИС XILINX VERSAL
Authors: Тарасов И.
Published: December 2021

Рассмотрены ПЛИС Xilinx Versal. Отмечено, что их особенностью является добавление на кристалл матрицы процессоров с архитектурой VLIW. Приведена информация об архитектуре, характеристиках и областях применения ПЛИС Xilinx Versal.
Video Conferencing WebApp
Authors: Majhi Sanjay
Published: December 2021

Abstract: During the last few years, video conferencing has become very popular and very reliable as a tool to bridge the gap where travel is not an option. And the COVID-19 epidemic has also led to lockdown orders that have led to dramatic changes in the way people work. The number of people working in the home (WFH) had increased significantly during the pandemic. The need for distance learning has also increased and has become a compulsory education system in the midst of this current situation. The Companies are also adopting an innovative recruitment process at such time. So to address this issue, our project aims to build a conference app that helps to provide communication between people through audio conferencing, video conferencing, screen sharing and messaging in real time. In this, we have created group video chat with the help of WebRTC technology and socket programming. Also we have added real-time chat feature and screen share feature. We had created the web app using Jquery for front end and node.js express.js for signaling server and real time database of Firebase for storing chats and user information. WebRTC helped us to create peer to peer connection and with the help of sockets we have done transfer of sdp packets and ice candidates. We have discussed extensively about them in our paper. Keywords: Video conferencing app, sockets, webrtc, peer-to-peer, realtime data transfer
Brain Tumor Classification using Deep Learning Algorithms
Authors: Kadam Ankita
Published: December 2021

Abstract: A Brain tumor is one aggressive disease. An estimated more than 84,000 people will receive a primary brain tumor diagnosis in 2021 and an estimated 18,600 people will die from a malignant brain tumor (brain cancer) in 2021.[8] The best technique to detect brain tumors is by using Magnetic Resonance Imaging (MRI). More than any other cancer, brain tumors can have lasting and life-altering physical, cognitive, and psychological impacts on a patient’s life and hence faster diagnosis and best treatment plan should be devised to improve the life expectancy and well-being of these patients. Neural networks have shown colossal accuracy in image classification and segmentation problems. In this paper, we propose comparative studies of various deep learning models based on different types of Neural Networks(ANN, CNN, TL) to firstly identify brain tumors and then classify them into Benign Tumor, Malignant Tumor or Pituitary Tumor. The data set used holds 3190 images on T1-weighted contrast-enhanced images which were cleaned and augmented. The best ANN model concluded with an accuracy of 78% and the best CNN model consisting of 3 convolution layers had an accuracy of 90%. The VGG16(retrained on the dataset) model surpasses other ANN, CNN, TL models for multi-class tumor classification. This proposed network achieves significantly better performance with a validation accuracy of 94% and an F1-Score of 91. Keywords: Artificial Neural Network(ANN), Convolution Neural Network (CNN), Transfer Learning(TL), Magnetic Resonance Imaging(MRI.)
LOGIC PRO X MÜZİK KAYIT PROGRAMI İLE UD ÇALGISINDAN SAMPLE (ÖRNEKLEME) ÜRETİMİ
Authors: ZİYAGİL Hakan Emre
Published: December 2021

Günümüzde bilgisayar kullanımın artması ve buna bağlı olarak yazılım firmalarının müzik kayıt programlarını güçlendirmesiyle birlikte müzik üreten bireylere (besteci, aranjör vs.) büyük kolaylıklar sağlanmıştır. Müzik teknolojilerinde ve ses kayıt programlarında kullanılan bu kolaylıklardan biri Sampler modülüdür. Bu modül sayesinde akustik bir çalgıdan alınan seslerin daha sonra tekrar kullanılması sağlanmaktadır. Böylelikle bilgisayar başında sample(s) üretilmiş olan akustik çalgıların orijinal sesleri kullanılabilmektedir. Bu araştırma kapsamında kullanılacak olan DAW (Digital Audio Workstation) Logic Pro X ve sampler modülü ise EXS 24 MKII’dir. Akustik tınısı ve kendine has karakteristik yapısı ile neredeyse tüm müzik türleri içinde kullanılan Ud, dünya geneline yayılmış çalgılar arasındadır. Bundan dolayı yerli-yabancı müzik üreten (aranjör, besteci vs.) kişilerin kendi oluşturdukları eserlerinin içerisinde kullanmak için ud seslerine ihtiyacı olmaktadır. Ud çalmayı bilmeyen aranjörler ya da besteciler, sampler modülü sayesinde üretecekleri müziklerde orijinal ud seslerini rahatlıkla kullanabilmektedirler. Bu araştırmanın amacı ud çalgısından elde edilecek olan ses/seslerin (sample/samples) hangi aşamalardan geçerek kayıt altına alındığı ve müzik kayıt programları içerisinde nasıl kullanıldığının gösterilmesidir. Bu sistemin öğrenilmesi ile birlikte müzik kayıt programlarını kullanan herkesin, istediği akustik çalgının seslerini sample hâline nasıl dönüştüreceği konusunda bilgi sahibi olması hedeflenmektedir.
Potentialities and limitations of Planosols with distinct depths of diagnostic horizon
Authors: Vieira Juciane Maria Santos Sousa , Romero Ricardo Espindola , Toma Raul Shiso , Anunciato Mota Jaedson Claudio , Costa Mirian Cristina Gomes
Published: December 2021

There is a variation in the depth of subsurface horizon of Planosols in semi-arid region, which may influence the agricultural potential and affect food production. The general aim of this study was to identify potentialities and limitations of two Planosols as a function of subsurface horizon depth. The adjacent profiles P1 and P2 were studied in Pentecoste (Ceará, Brazil). Morphological, physical, and chemical analyses were done aiming at soil characterization. Soil bulk density (BD), porosity, and penetration resistance (PR) were analyzed in a completely randomized split-plot design with four replicates to compare P1 and P2 and the horizons Ap and Btf. Btf was found at 62cm depth in P1 and at 18 cm depth in P2. Indicatives of water saturation were more evident in P2. The profile P1 showed lower hardness and higher friability, as well as higher acidity in subsurface (pHH2O from 4.4 to 4.7) and higher aluminum content (1.2cmolc kg-1). Both profiles were eutrophic and showed low contents of organic carbon (1.5 to 8.5g kg-1) and phosphorus (0.9 to 3.9mg kg-1). The sodium percentage in CEC was 9.1% in P1 and 5.5% in P2. Water retention increases in Btf compared with Ap was 7.3% in P2 and 2.7% in P1. Both profiles showed increase in BD in Btf, reaching 1.7g cm-3, while PR was higher in P2 (1.5 MPa). There are potentialities and limitations common to both soil profiles, but P1 has more physical potentialities and more chemical limitations than P2.
Soil vulnerability index to climatic variability in coffee regions of Colombia
Authors: Lince-Salazar Luz Adriana , Sadeghian-Khalajabadi Siavosh , Díaz-Poveda Vanessa Catalina
Published: December 2021

Global climate change is one of the main factors threatening agriculture. In this context, variations in precipitation have the strongest effect on soil fertility, plant nutrient availability, and erosion. This research aimed to assess soil vulnerability to climate variability in the central coffee-growing region of Colombia. This study analyzed soil components involved in the sustainability of the coffee production system as affected by extreme high and low precipitation events. For evaluation, three sensitivity indices were constructed, with a weighted aggregation structure and with weight values defined from expert knowledge. The indices were estimated by randomly selecting 432 coffee farms in the municipalities of Balboa and Santuario in Risaralda department and Salamina in Caldas department. The soil nutrient availability and conservation vulnerability index was moderate in the three municipalities (Balboa=2.87 and coefficient of variation-CV 13%; Santuario=2.88 and CV 10%; Salamina=2.9 and CV 9%). The soil leaching vulnerability index was very low in Balboa (4.33 and CV 3%) and Salamina (4.74 and CV 7%) and low in Santuario (3.57 and CV 19%). The soil loss vulnerability index was low in Balboa (3.32 and CV 10.03%) and Salamina (3.49 and CV 11.43%) and moderate in Santuario (3.13 and CV 9.34%). Lastly, the vulnerability of coffee-growing soil to climate variability was low in Balboa (3.33) and Salamina (3.45) and moderate in Santuario (3.09). Based on these results, in the three municipalities, coffee growers must introduce farming practices towards improving soil resilience and decreasing soil vulnerability to high and low precipitation extremes by adequately managing the sources and doses of fertilizers, soil conditioners, and compost and by implementing integrated management of weeds and litterfall.
Clasificación espacial del suelo urbano por el valor especulativo del suelo e imágenes MSI satelitales usando K-MEANS, Huancayo, Perú
Authors: Peña-Zamalloa Gonzalo Rodolfo
Published: December 2021

The city of Huancayo, like other intermediate cities in Latin America, faces problems of poorly planned land-use changes and a rapid dynamic of the urban land market. The scarce and outdated information on the urban territory impedes the adequate classification of urban areas, limiting the form of its intervention. The purpose of this research was the adoption of unassisted and mixed methods for the spatial classification of urban areas, considering the speculative land value, the proportion of urbanized land, and other geospatial variables. Among the data collection media, Multi-Spectral Imagery (MSI) from the Sentinel-2 satellite, the primary road system, and a sample of direct observation points, were used. The processed data were incorporated into georeferenced maps, to which urban limits and official slopes were added. During data processing, the K-Means algorithm was used, together with other machine learning and assisted judgment methods. As a result, an objective classification of urban areas was obtained, which differs from the existing planning.
Sustainable Development Goals in 2020
Authors: Chepusov Anton G.
Published: December 2021

This article provides a brief overview of the term sustainable development and its brief characteristics. The author considers the details of the ongoing changes in the current macroeconomic context of the global pandemic. The author concludes that only a few indicators have improved their dynamics in 2020-2021. In the future, inertial development is predicted for most of the key areas of sustainable development. Therefore, the article shows that achieving the SDGs on a global scale by 2030 is nothing more than an indicative and currently unattainable goal.
Molecular characterization of pathogenic OTOA gene conversions in hearing loss patients
Authors: Laurent Sacha , Gehrig Corinne , Nouspikel Thierry , Amr Sami S , Oza Andrea , Murphy Elissa , Vannier Anne , Béna Frédérique Sloan , Carminho-Rodrigues Maria Teresa , Blouin Jean-Louis , Van Hélène Cao , Abramowicz Marc , Paoloni-Giacobino Ariane , Guipponi Michel
Published: December 2021

Bi-allelic loss-of-function variants of OTOA are a well-known
cause of moderate-to-severe hearing loss. Whereas non-allelic homologous
recombination-mediated deletions of the gene are well known, gene
conversions to pseudogene OTOAP1 have been reported in the
literature but never fully described nor their pathogenicity assessed.
Here, we report two unrelated patients with moderate hearing-loss, who
were compound heterozygotes for a converted allele and a deletion
of OTOA. The conversions were initially detected through
sequencing depths anomalies at the OTOA locus after exome
sequencing, then confirmed with long range polymerase chain reactions.
Both conversions lead to loss-of-function by introducing a premature
stop codon in exon 22 (p.Glu787*). Using genomic alignments and long
read nanopore sequencing, we found that the two probands carry stretches
of converted DNA of widely different lengths (at least 9 kbp and around
900 bp,
respectively).
The anti-inflammatory feature of glucagon-like peptide-1 and its based diabetes drugs -- Therapeutic potential exploration in lung injury
Authors: Pang Juan , Feng Jia Nuo , Ling Wenhua , Jin Tianru
Published: December 2021

Since 2005, GLP-1 receptor (GLP-1R) agonists (GLP-1RAs) have been
developed as therapeutic agents for Type 2 diabetes. GLP-1R is not only
expressed in pancreatic islets but also in other organs, especially the
lung. Extra-pancreatic expression of GLP-1R triggered intensive
investigations on extra-pancreatic functions of GLP-1RAs, aiming to
repurpose them into therapeutic agents for other disorders. Intensive
studies have demonstrated promising anti-inflammatory features of
GLP-1RAs. Whether those features are directly mediated by GLP-1R
expressed in majority of immune cells remains controversial. Following a
brief review on GLP-1 as incretin and the development of GLP-1RAs as
therapeutic agents, we summarized our current understanding on
anti-inflammatory features of GLP-1RAs. The main part of this review is
literature discussions on GLP-1RA utilization in chronic and acute lung
injuries, including studies on combined use of MSC-based therapy and the
GLP-1RA liraglutide in LPS-induced acute lung injury. This is followed
by a summary and perspective.
INSERÇÃO CURRICULAR DA TEMÁTICA SUSTENTABILIDADE EM CURSOS DE GRADUAÇÃO EM CIÊNCIAS CONTÁBEIS DE UNIVERSIDADES PÚBLICAS PARANAENSES
Authors: Dos Santos Anne Carolina , Neumann Marguit , Mattiello Kerla
Published: December 2021

O objetivo da pesquisa é analisar de quais formas os cursos de graduação em Ciências Contábeis de universidades públicas do Paraná inserem a temática sustentabilidade nos Projetos Pedagógicos, desde o ano de 2002. Utilizou-se da análise de conteúdo tendo como base Projetos Pedagógicos de seis cursos. Os resultados indicam que os cursos evoluíram ao incorporar a temática sustentabilidade, em razão do aumento da consideração de conteúdos nas disciplinas. A evolução foi detectada a partir de 2012, influenciados por documentos de avaliação e pelas diretrizes curriculares do curso. A forma de inserção Crossdisciplinar foi predominante com maior abrangência do social, indicando que há desconexão entre o socioambiental e o econômico. Logo, a adoção da temática sustentabilidade nos cursos investigados está em fase de amadurecimento, porém, mesmo que seja estabelecida por Lei, sua inserção nos Projetos Pedagógicos depende dos indivíduos. Diante disso, questiona-se a eficácia do caráter coercitivo, pois, pode induzir a adoção cerimonial. Neste caso, legislações específicas demonstraram ser eficazes, indicando a necessidade de atribuírem maior peso na temática sustentabilidade. Esta pesquisa contribui com a literatura, diante da carência de estudos. As contribuições práticas advêm de recomendações para o cumprimento das legislações pertinentes, além de contribuir para eliminar privações de liberdade no que se refere a ausência da temática sustentabilidade na educação do contador. E, ainda, para o bem-estar da sociedade, pois, organizações geram externalidades negativas.
„Hrvatski problem“ i Hrvat-demokrat Zdravko Kovačević
Authors: Artuković Stanislav , Miškulin Ivica
Published: December 2021

Autori donose
prijepis programskog teksta istaknutog pripadnika Demokratske stranke
slavonsko-srijemskog prostora, odvjetnika i (kako se tada govorilo) kraljevskog
javnog bilježnika u Slatini Zdravka Kovačevića. U njemu se iznose razmišljanja
o ključnom unutarnjem političkom problemu Kraljevine Srba, Hrvata i Slovenaca,
nezadovoljstvu Hrvata novonastalim stanjem, s posebnim naglaskom na ideologiju
jugoslavenskog unitarizma. Protkana su (zbog slabe očuvanosti stranačkog i
drugog arhivskog gradiva) vrijednim (i u historiografiji uglavnom zanemarenim)
osobnim iskustvima koja je Kovačević imao u prvim godinama političkog
djelovanja u novoj državi. Dokument je popraćen temeljnim podatcima o samom
Kovačeviću i kraćom analizom teksta, kao i motivima kojima je potaknut te
reakcijama na nj.
Impact of grape pomace as a cultivation substrate on the Pleurotus ostreatus chemical and biological properties
Authors: Doroski Ana , Klaus Anita , Kozarski Maja , Nikolic Biljana , Vunduk Jovana , Lazic Vesna , Djekic Ilija
Published: December 2021

The objective of this study was to develop a single quality index of chemical
characteristics of Pleurotus ostreatus extracts on 7th and 14th day of its
shelf life, derived from the mushroom fruiting bodies. P. ostreatus was
cultivated on four substrates containing different ratio of wine industry
waste-grape pomace (P) and wheat straw (S): 100P, 80P20S, 50P50S, 20P80S.
Four quality parameters of P. ostreatus mushroom extracts, i.e.
antioxidative parameters: ABTS+ and DPPH? free radical scavenging
capability, total phenolic compounds (TPC) and total polysaccharides (TPS)
were used to define the final extract quality index. Analysis indicated 100P
and 80P20S as the samples cultivated on the substrate with higher percent of
grape pomace, as the best quality at the 7th day of its shelf life. On the
other hand, final quality score indicated 50P50S and 20P80S, cultivated on a
substrate with a lower percent of grape pomace, as the best quality samples
at the 14th day of its shelf life. According to the results, samples
cultivated on a higher pomace content substrate are of better quality in a
shorter storage time period.
Removal of methylene blue by biosorption onto Stipa tenacissima L. (Alfa) plants: Kinetics, equilibrium and thermodynamic studies
Authors: Ladjali Samir , Dahdouh Nadjib , Amokrane Samira , Mekatel El , Nibou Djamel
Published: December 2021

This study examines the ability of Stipa tenacissima L. (Alfa) to biosorb the
Methylene Blue dye. Biosorption tests were performed in aqueous solution
based on certain essential parameters such as solution?s pH (2-12),
solid/liquid ratio (1-6 g/L), initial dye concentration (25-125 mg/L) and
contact time (0-300 min). The Langmuir, Freundlich, Temkin and Elovich
models were applied. It was found that the equilibrium data could be fitted
to the Langmuir isotherm for MB biosorption with a maximum capacity qmax 55,
95 mg/g. The kinetic study shows that the experimental data correspond to
the pseudo-second order kinetic model. The negative Gibbs values free energy
?G? reveal the spontaneity of MB biosorption at the surface of Stipa
tenacissima L. The positive value of ?H? reveals the endothermic nature of
the process.
Characterization of new adsorbent prepared from apricot stones activated carbon mixed with amorphous SiO2 from Algerian diatomite for removal of p-nitroaniline
Authors: Tizi Hayet , Berrama Tarek , Hamane Djamila , Ferrag-Siagh Fatiha , Bendjama Zoubida
Published: December 2021

This work aims to evaluate the adsorption efficiency of p-nitroaniline (PNA)
onto apricot stones activated carbon (ASAC) mixed with treated extract of
amorphous SiO2 (TEAS), prepared from Algerian diatomite (AD). The best
removal percentage (85%) is obtained for a ratio ASAC/TEAS (1/1). Adsorbent
characteristics are investigated by the Brunauer-Emmett-Teller (BET), the
scanning electron microscope (SEM), infrared spectroscopy (IR), X-ray
fluorescence (XRF) and X-ray diffraction (XRD). The impregnation of TEAS and
ASAC produces good adsorbent properties towards PNA especially in the ratio
(1/1) and an increase in the specific surface. The isotherm data are well
fitted by the Langmuir and Freundlich models. The maximum PNA uptake
obtained is 94.34 mg g-1. The performances of ASAC/TEAS for the PNA
adsorption were compared with some adsorbents previously studied for the
same purpose, and results show that the composite in the present work
exhibit better performances. The adsorption behavior of the concerned
material is explained on the basis of its chemical nature and porous
texture.
Optimization of baker`s yeast production on grape juice using response surface methodology
Authors: Sawsan Mahmood , Ali Ali , Ayhem Darwesh , Wissam Zam
Published: December 2021

There is an increasing interest in improving biological processes, including
fermentation processes, improving fermentation conditions is difficult, as it
requires the use of an appropriate improvement method that allows operating
the biological fermenter under optimal conditions in order to obtain the
largest possible amount of the final product. The aim of this work was to
succeed in examples of fermentation conditions to produce the largest
possible quantity of dry yeast biomass Saccharomyces cerevisiae using grape
juice as the sole carbon source. The optimum values of five factors that have
an effect on the production of dry biomass from baker`s yeast were
determined. The design of the experiments was carried out using the central
composite experimental design (CCD) and the number of experiments according
to the design was (54) experiments, the response surface methodology method
was used to determine the best possible amount of production of yeast, and
has reached (41.44 g/L) after 12 hours of fermentation, under the following
optimal conditions (temperature (30.11??), pH (4.75), sugar concentration
(158.36 g/L), the ratio of carbon to nitrogen (an essential nutrient for
yeast growth ) is (11.9), initial concentration of yeasts (2.5 g/L), the
amount of urea was 6.65 g/L and the amount of ammonium sulfate used was 6.65
g/L, so that the concentration of added urea and ammonium sulfate was
(50-50)% and the required C/N ratio was achieved, and the used agitation
speed was equal to 200 r.p.m during the fermentation process. The fermenter
power of the obtained yeast was 470 ml. Three kinematic models (Monod,
Verhulst, and Tessier) were also selected for the purpose of studying the
kinetic performance of Saccharomyces cerevisiae yeast. Monod and Tessier`s
models did not give satisfactory results, while the best results were
according to the Verhulst model. Also, the Leudeking Piret model has also
been successfully used to predict substrate consumption during fermentation
time.
Health-related factors for work participation in persons with spinal cord injury in Finland
Authors: Eskola Kaarina , Koskinen Eerika , Anttila Heidi , Tallqvist Susanna , Bergman Paula , Kallinen Mauri , Hämäläinen Harri , Kauppila Anna-Maija , Täckman Anni , Vainionpää Aki , Arokoski Jari , Rajavaara Marketta , Hiekkala Sinikka
Published: December 2021

Objective: To explore work participation and the health-related factors affecting work participation among the Finnish Spinal Cord injury (FinSCI) study population (n = 884).Methods: A cross-sectional explorative observational study in the FinSCI community survey applying Patient-Reported Outcomes Measurement Information System (PROMIS®) forms on Social Health and Global Health. Analyses of socio-demographic and injury-related data were performed.Results: Employment among the study population (n = 452) was 26.5%. Physical, Mental, Social and General Health were better in the employed group compared with work-age persons not working. Logistic regression showed that work participation was related to all health domains, but Physical Health and Ability to Participate in Social Roles and Activities in Social Health were the strongest indicators of likelihood of being at work. Paraplegia and young age were associated with increased likelihood of work participation. Conclusion: The first national survey among people with spinal cord injury in Finland shows low level of employment. The results suggest that pain, physical function, and ability to participate in social roles should be monitored by health and vocational professionals when assessing a person’s likelihood of being in work.
Lay abstractThe data source for this study was the Finnish Spinal Cord Injury Study (FinSCI), which collected extensive information from people with spinal cord injury about their health and employment status. A total of 452 responders from the FinSCI survey were included in the current study. The employment rate in the FinSCI study population was low (26.5%) and the majority of those not in work (73.5%) were receiving a disability pension. The analysis of health factors showed that all health aspects were better in the employed group compared with the group who were not working. Physical Health, Ability to Participate in Social Roles and Activities, less severe injury, and young age were associated with likelihood of work participation. This study provides up-to-date self-reported data for the spinal cord injury population and health professionals, helping to identify health-related problems that could be barring employment.
MONITORIA ACADÊMICA EM ZOOLOGIA DOS INVERTEBRADOS: UM RELATO DE EXPERIÊNCIA
Authors: Martins dos Santos Pereira Marianne , Silva Oliveira João Pedro , Almeida Pinheiro Rodrigo , Bispo dos Santos Claudimary
Published: December 2021

Na disciplina de zoologia dos invertebrados, compete ao monitor, na parte prática, exercer suas funções de auxiliar, mediar, socializar, lecionar e pesquisar. O artigo objetiva relatar experiências vivenciadas na monitoria acadêmica de zoologia dos invertebrados, discorrendo, principalmente, acerca das metodologias desenvolvidas. Nesse sentido, foi disponibilizada uma aula prática após o estudo teórico de cada filo do reino animal. A maioria dessas práticas foram desenvolvidas no laboratório multidisciplinar da universidade e neste artigo foram descritas cinco delas, relacionadas com os seguintes conteúdos: Protozoa, Porifera, Mollusca e Arthropoda. Participaram das aulas os alunos matriculados nas disciplinas de zoologia dos invertebrados I e II. Estes mostraram interesse, curiosidade e atenção durante os momentos de visualização no microscópio, revisão, dissecação e montagem da coleção dos artrópodes. Portanto, conclui-se que a monitoria contribui tanto para a formação acadêmica dos monitores quanto para um melhor andamento da disciplina, favorecendo o desenvolvimento das metodologias aplicadas.
Quo vadis, kodinomaisuus? Käsitteen tarkastelua virallislähteissä
Authors: Kaskiharju Eija
Published: December 2021

Artikkelin tutkimuskohde on kodinomaisuuden käsite. Kodinomaisuus on kirjattu lainsäädäntöön, hallituksen esityksiin ja muihin virallislähteisiin. Tutkimus on luonteeltaan ei-empiirinen asiakirjoihin perustuva kuvaileva analyysi. Aihetta ei ole aiemmin tutkittu tästä näkökulmasta. Tarkastelen kodinomaisuuden käsitettä kolmen lain ja niitä koskevien esitöiden sekä kahden oikeuskäytäntötapauksen pohjalta. Tulosten mukaan kodinomaisuuden käsitteen alkuperä on kaupallisessa toiminnassa, josta se on siirtynyt gerontologiseen tutkimukseen. Kansainvälinen tutkimus on tuottanut useita näkökulmia kodinomaisuuteen. Suomessa se on yksi käsite virallislähteissä, jotka ohjeistavat ja määräävät iäkkäiden asumisen sisältöjä. Kodinomaisuus on normitettu käsite, joka on yhtäältä kuvaava ja toisaalta laatutekijä ympärivuorokautisessa hoidossa. Ennen kaikkea se on mielikuvia rakentava käsite.
Development and Testing of a Roleplaying Gamification Module to Enhance Deeper Learning of Case Studies in an Accelerated Online Management Theory Course
Authors: Pereira Audrey Smith , Wahi Monika
Published: December 2021

Research has established that “cognitive rehearsal,” (CR) or the visualization of application of a behavioral response to a situation, can increase self-efficacy through vicarious experience, but is challenging to induce online. Online higher education curricula can include collaborative game-based learning (GBL) in the form or roleplaying, which can facilitate CR. The purpose of this study was to develop an online GBL module to facilitate CR in online business graduate students learning management theory case studies, and to evaluate its ability to induce CR. A convenience sample of students voluntarily participated in a proof-of-conduct study using a mixed-methods design to gauge whether use of the module facilitated CR, a descriptive and thematic analysis was conducted. Data were collected from 106 students within two course sections in an online Master of Business Administration (MBA) program. The module was used as an optional supplement to a management case study assignment and approximately 50% of students used it. Scores on the assignment were compared between students who used the module and students who did not, and those who did scored statistically significantly higher (p = 0.0003). Students reported in a survey that the module induced CR about applying management theory. Students also expressed satisfaction with the module and provided feedback for its improvement in the areas of format and content. Our findings suggest that collaborative roleplaying GBL and other methods to induce CR in online higher education should be explored and formally studied.
Developing Peer Review of Instruction in an Online Master Course Model
Authors: Haubrick John , Cruz Laura , Levy Deena R.
Published: December 2021

In this study we looked at how participation in a peer-review process for online Statistics courses utilizing a master course model at a major research university affects instructor innovation and instructor presence. We used online, anonymous surveys to collect data from instructors who participated in the peer-review process, and we used descriptive statistics and qualitative analysis to analyze the data. Our findings indicate that space for personal pedagogical agency and innovation is perceived as limited because of the master course model. However, responses indicate that participating in the process was overall appreciated for the sense of community it helped to build. Results of the study highlight the blurred line between formative and summative assessment when using peer review of instruction, and they also suggest that innovation and presence are difficult to assess through short term observation and through a modified version of a tool (i.e., the Quality Matters rubric) intended for the evaluation of an online course rather than the instruction of that course. The findings also suggest that we may be on the cusp of a second stage for peer review in an online master course model, whether in-person or online. Our findings also affirm the need for creating a sense of community online for the online teaching faculty. The experiences of our faculty suggest that peer review can serve as an integral part of fostering a departmental culture that leads to a host of intangible benefits including trust, reciprocity, belonging, and, indeed, respect.
Introduction to the Special Issue: Select Papers Presented at the 2020 OLC Accelerate Conference and the 2021 OLC Innovate Conference
Authors: Moskal Patsy
Published: December 2021

Each year, OLJ presents a special section devoted to research shared at the Online Learning Consortium conferences. We are happy to present five research articles selected from the many presented at OLC Accelerate, held virtually November 9-18, 2020 and OLC Innovate, held virtually March 15-19, 2021. We invite the readers to consider presenting their research to OLC conferences in the future and submitting to OLJ to share their work with others in the field.
An Exploratory Examination of Student-Led, Asynchronous Collaborative Online Discussions in Fostering Higher-Order Cognitive Skills and Ethical Leadership Learning
Authors: McCarron Graziella Pagliarulo , Olesova Larisa , Calkins Brianna
Published: December 2021

Previous studies have contextualized student-led, asynchronous online discussions as collaborative learning experiences that positively impact students’ learning and foster higher order cognitive skills. From a leadership education perspective, student-led discussions have come to the fore as a helpful resource for deepening learning because of their focus on collaboration and shared leadership. While literature on student-led online discussions, leadership learning, and cognitive skill is plentiful, there is no single study that explores all these elements together or fully points to how practicing meaning-making in online, asynchronous leadership courses can inform larger cognitive processes. Thus, the purpose of this conceptual content analysis-based study was to examine 35 undergraduate students’ collaborative discussion board posts at the beginning, middle, and end of an online, asynchronous Ethics and Leadership class to assess not only if and to what extent students expressed cognitive skills, in general, but also if and to what extent they understood ethical leadership via these types of discussions. Further, from an exploratory lens, this study examined if there was a relationship between expression of higher order cognitive skills and more complex ethical leadership understanding. Results indicate that, while students achieved higher order cognitive skills and more holistic ethical leadership understanding overall, robustness of student engagement could be situational in nature and expressions of cognitive skills and ethical leadership understanding tapered as the course progressed. Additional findings and implications are discussed.
OLJ December 2021 25(4)
Authors: Rice Mary Frances
Published: December 2021

Full Issue
EPIDEMIOLOGICAL ASSESSMENT OF DYMAMICS OF THE PREVALENCE AND INCIDENCE OF THE THYROID GLAND DISEASES IN UKRAINE AND CHERNIVTSI REGION
Authors: Kamyshna І.І. , Pavlovich L.B. , Maslyanko V.A. , Chornenka Zh.A.
Published: December 2021

Objective – to assess the dynamics of the prevalence and incidence of the thyroid diseaseamong the adult population of Ukraine and Chernivtsi region during 2015-2020.Material and methods. A comparative analysis of official accounting and reportingstatistics of the Ministry of Health of Ukraine and the main indicators of the endocrinologyservice of Chernivtsi region on the prevalence and incidence of adult pathology of thethyroid gland over the past 5 years.Results. In Ukraine, the number of pathologies of the thyroid gland has increased,accounting for 48% of the total incidence of endocrine diseases. The most commonpathology is diffuse and nodular goitres. Their level in the western region, includingChernivtsi region, is higher than the national average. In Ukraine the incidence ofhypothyroidism has increased 20.3% for 5 years. Thyrotoxicosis increased 9.1%, andthe prevalence of thyroiditis increased 16.8%. The increase in the Chernivtsi region wasslightly lower. The high frequency of thyroid pathologies depends on the imbalance oftrace elements and vitamins in the diet against a background of iodine deficiency in thediet, environmental degradation and insufficient preventive measures.Conclusions. The analysis shows that in the western regions of Ukraine it is necessaryto apply a differentiated approach to the diagnosis, treatment and prevention of patientswith various thyroid diseases.
ULTRASTRUCTURAL ORGANIZATION OF NEURONS OF THE LATERAL PREOPTIC NUCLEUS OF THE HYPOTHALAMUS OF OLD RATS UNDER VARIOUS LIGHT CONDITIONS
Authors: Yosypenko V.R. , Bulyk R.Ye. , Kryvchanska M.I. , Lukan Y.R.
Published: December 2021

Purpose – to study the changes in the ultrastructure of neurons of the lateral preopticnucleus (LPON) of the hypothalamus of old rats under various light conditions.Material and methods. The experiments were carried out on 36 old white male rats.The material was fixed in a 2.5% solution of glutaraldehyde, prepared on the basisof phosphate buffer with a pH of 7.2–7.4. Then, postfixation was performed in a 1%solution of osmium tetraoxide and dehydrated in propylene oxide, after which it waspoured into a mixture of epoxy resins. Ultrathin sections made on an ultramicrotomeLKB-3 were contrasted with uranium acetate and lead citrate according to the Reynoldsmethod and studied under electron microscope TEM - 125 K.Results. Studies of LPON neurons under the standard light mode revealed nuclei withuneven contours. The nucleoli are quite large. The neuroplasm contains well-developedtubules of the rough endoplasmic reticulum (ER) and small cisternae of the Golgi complex(GC). Mitochondria are rounded, small, with moderately pronounced cristae. Underconditions of round-the-clock darkness, we have found that the cell nuclei are rounded,less often determined by the nucleoli. In the neuroplasm there are locally dilated tubulesof the ER and cisternae of the GC, mitochondria with enlightened matrix and fragmentedcristae. Under conditions of round-the-clock illumination, the nuclei of the rounded formwith uneven contours of a nuclear membrane forming deep intussusception are revealed.Nucleoli were rarely identified. In the hyaloplasm, locally dilated tubules of the ERare identified. Mitochondria are small in size with an enlightened matrix and reducedcristae.Conclusions. The obtained results of submicroscopic examination of LPON neuronsof the hypothalamus of old rats revealed their relatively increased functional activityin the dark period. Under conditions of round-the-clock lighting, more pronouncedhypertrophic and initial destructive changes of the nuclei and organelles of the neuronsof the LPON of the hypothalamic were revealed, compared with the animals that wereunder the conditions of round-the-clock darkness. This is confirmed by the change in theultrastructure of nerve cells at 2 am the appearance of "dark" cells.
The role of transforming growth factor-β and of matrix metalloproteinase 9 in immunopathogenesis of endometriosis associated with infertility
Authors: G. D. Koval
Published: December 2021

In the development of endometriosis and infertility, associated with it, immunological processes play an important role, ant they are characterized by high activity of cytokines and growth factors (e.g., transforming growth factor -β (TGF-β)) and increased invasiveness of ectopic endometrium, including activity of matrix metalloproteinases (MMP). TGF-β exhibits different biological properties and plays a key role in the migration, proliferation and differentiation of cells. The concentration of TGF-β in serum and peritoneal fluid of 65 women with external genital endometriosis and infertility has been studied. We found an increase of TGF -β in peritoneal fluid, which is associated with an increased activity of MMP9 in the ectopic endometrium.
Metabolic disorders in hypertension patients as scientific area of the department of family medicine
Authors: S. V. Biletskyi  , O. A. Petrynych  , T. V. Kazantseva
Published: December 2021

The paper generalizes the results of a scientific research at the department of family medicine concerning the study of metabolic disorders in hypertension patients and their changes caused by a pathogeneticaly based treatment.