bluuebunny/crossref_metadata_2025 huggingface dataset:
Marfan syndrome associated with type 1 diabetes and autoimmune thyroiditis in a 27 years old female patient - Case presentation
Authors: Bernadett Berecki , Noemi Iakab , Maria Szabó Monica Iudita
Published: January 2022

Introduction: Marfan syndrome (MFS) is a genetically determined connective tissue disorder caused by a mutation in the FBN1 gene, located on chromosome 1, which regulates the production of the glycoprotein Fibrillin 1. This results in different connective tissue diseases, especially cardiovascular involvement. Objective: The aim of our presentation is the description of a case in which type 1 autoimmune diabetes and thyreoiditis coexists in a previously undiagnosed patient with MFS. Case presentation: A 27-years-old female patient presented to the emergency department with a 6 months long polyuria-polydipsia syndrome, with weight loss of -10kg. The onset of diabetes manifested with severe ketoacidosis (blood glucose=674 mg/dl, pH=7,036, urinary ketone bodies=159 mg/dl). Pathological laboratory findings include C-peptide=212 ng/ml, anti glutamic acid decarboxylase (GAD) = 5,1UI/ml, ATPO=558 UI/ml. Clinical features of MFS could be recognised, like dolicocephalic face with enophthalmus, height: 184 cm, weight: 40 kg with a BMI of 11,81 kg/m2 respectively 50 kg and 14,77 kg/m2 before weight loss; long limbs, arachnodactyly, kyphoscoliosis, mitral systolic murmur. Imaging procedures showed atrial septal defect with a 6 mm bidirectional shunt, the ascending aorta, the trunk and the aortic isthmus were dilated, mitral valve prolapse, tricuspid valve insufficiency and dilatation of the right heart cavities, interatrial septal aneurysm and pulmonary hypertension. The ECG showed a right branch block. Ophthalmologic examination confirms the lens subluxation. Discussion: The etiology of diabetes and thyroiditis has proven to be autoimmune. With the introduction of base-bolus insulin therapy glycemic control was obtained and beta-blocker treatment was started for the cardiac involvement. Summary: This particular case is unique due to the fact that associates two serious lifelong diseases. MFS should be considered on the basis of morphological characteristics, which requires further investigation due to its serious long term complications.
Comments on the Hungarian pharmacopoeias in the 19th century
Authors: Árpád Gyéresi , Mihály Kata , Mária Gyéresi
Published: January 2022

Before 150 years the first Hungarian pharmacopoeia was compiled in 1871 as a result of nearly one century of national efforts. The first four editions were published in two languages, Hungarian and Latin. The second edition (1888) became better than the first one showing significant progress mainly in terms of speciality language.

Based on the first edition Prof. Kálmán Balogh, medical doctor, published an encyclopaedic commentary, which is an unparalleled source-work of the contemporary Hungarian pharmacological literature.

Geyza Karlovszky and Lajos Winkler issued a pocket edition (“Pocket Commentary”) based on the chemistry articles of the second edition of the pharmacopoeia, which became an important practical handbook of pharmacist education.
International Recognition of Own Brands - The Case of the Portuguese Footwear Industry
Authors: Dias Pinto Ribeiro Maria Clara , Silva Ricardo Jorge , da Costa Pinho Cláudio Leandro , da Silva Martins Francisco Vitorino
Published: January 2022

Portugal is one of the world’s largest footwear exporters and a leader in the fashion footwear segment However, these exports are mostly under private level brands, and not own brands. The aim of this work is to analyse strategies for the implementation of own brands within the scope of International Trade, pursuing international recognition. The exploratory investigation is based on a questionnaire to companies, owners of own brands and with international experience. Most of the companies studied are growing, family-based SMEs. The results indicate that Portuguese brands exhibit at European fairs, with little international recognition (contrary to what happens with the footwear industry). With the application of the Principal Component Analysis, it is concluded that the classic means of promotion and the new means of communication via social networks are not seen in an integrated, complementary way. Analysing the interdependence of the main components, it is concluded that when the industry's action is relevant in the business perspective, it appears that there is a significant number of companies that follow these initiatives. Only companies with development/innovation work show motivation to create their own brands. International recognition is explained by the promotion of the sector and the export dynamics of companies.
Respon Galur-galur Harapan Padi Sawah Dihaploid terhadap Salinitas pada Fase Bibit
Authors: Anggita Duhita Anindyajati  , Bambang Sapta Purwoko  , Iswari Saraswati Dewi  , Willy Bayuardi Suwarno
Published: January 2022

Tantangan pemulia padi ke depan bertambah seiring dengan terjadinya perubahan iklim yang menyebabkan peningkatan salinitas lahan pertanian. Salinitas dapat mengakibatkan penurunan pertumbuhan dan kehilangan hasil yang besar dalam produksi padi. Tujuan penelitian ini ialah mengevaluasi toleransi salinitas galur-galur harapan padi sawah doubled-haploid /dihaploid (DH) hasil kultur antera pada fase bibit. Penelitian dilaksanakan di rumah kaca dari bulan Desember 2018 sampai Januari 2019. Penelitian dilakukan secara hidroponik dan disusun berdasarkan split plot rancangan kelompok lengkap teracak dengan empat ulangan. Petak utama ialah konsentrasi NaCl (0 mM dan 120 mM) dan anak petak berupa genotipe padi yang terdiri atas 14 galur DH, 4 VUB, pembanding toleran (Pokkali), dan pembanding peka (Inpara 4). Evaluasi pertumbuhan bibit dan skoring kerusakan visual bibit dilakukan 14 hari sesudah pemberian NaCl. Hasil penelitian menunjukkan konsentrasi NaCl 120 mM menyebabkan penurunan tinggi bibit, panjang akar, jumlah daun, jumlah anakan, bobot basah tajuk, bobot basah akar, bobot kering tajuk, bobot kering akar, bobot basah biomassa, dan bobot kering biomassa. Penurunan tinggi bibit dapat dipertimbangkan sebagai karakter penting dalam penapisan toleransi salinitas pada fase bibit. Hasil skoring terhadap kerusakan visual menghasilkan 11 galur DH dan 2 VUB toleran serta 3 galur DH dan 2 VUB moderat toleran.

Kata kunci: hidroponik, kultur antera, penapisan, toleransi
La crisis hídrica, señal para la transformación
Authors:   Instituto Mexicano de Tecnología del Agua, Morelos, México, Pedrozo Acuña Adrián
Published: January 2022

En el 2021, las múltiples crisis que enfrentamos como humanidad y su interrelación con el bienestar de las personas quedaron expuestas.
Perspectives of Pharmacists on the Structure, Decision-Making, and Communication Practices of Multidisciplinary Cancer Teams in Alabama
Authors: Gnagna-Waka Moano , Adunlin Georges , Boyd Katie , Jumbo-Lucioni Patricia , Bolaji Bolanle , Asare Matthew
Published: January 2022

Introduction: A multidisciplinary team (MDT) approach within cancer care settings is increasingly being adopted to improve patient outcomes due to the rising complexity of diagnosis and treatment. This study aims to explore the perspective of pharmacists on the structure, decision-making process, and communication practices of cancer MDTs.
Methods: A 25‐item online questionnaire was distributed to oncology‐related clinical pharmacists in Alabama. Data were analyzed using descriptive statistics.
Results: A total of 15 pharmacists completed the survey. More than half of the respondents reported that MDT meetings were held mostly in person on a set schedule. While physicians primarily facilitated the meetings, patients and/or their caregivers were largely not invited to participate in them. The treating physician oversaw delivering and update to the patient and/or their caregivers after the MDT meetings. Most respondents indicated that positron emission and computed tomography were the most common sources of information available at initial case presentations. Overall, respondents strongly agreed that they felt comfortable sharing their opinions with others health professionals during MDT meetings.
Conclusions: This study provides evidence that oncology pharmacists are involved in MDT decision-making processes and communications but suggests the need to promote conditions to further their participation.
Isolated Nail Pigmentation Induced by Minocycline: A Case Report
Authors: Clark Abigale , Ambur Austin , Nathoo Rajiv
Published: January 2022

Isolated pigmentation of the nails induced by minocycline therapy is an uncommon occurrence that has only been reported in a handful of cases. In the reported cases of isolated nail discoloration, it has been suggested that nail discoloration may occur preceding other sites of pigmentary changes. As certain types of minocycline-induced pigmentation can be permanent, it is important for clinicians to be aware of this association and discontinue therapy as soon as pigmentary changes are noticed. In this report, we present a case of isolated nail discoloration in the setting of prolonged minocycline therapy for the treatment of rosacea.
Features of the dynamics of engines with crank mechanism “Pancake”
Authors:   Yaroslavl State Technical University, Yaroslavl, Russia, Yamanin A.I.
Published: January 2022

The principal possibility of using the “Pancake” crank mechanism in three-cylinder four-stroke engines of supplementary power plants auxiliary is shown.
Reducing the dynamic loading of the gas turbine engine
Authors:   St. Petersburg State Marine Technical University, St. Petersburg, Russia, Babanin N.V.
Published: January 2022

The theoretical analysis of the dynamic features of the engine being designed and the results of the corresponding calculations, however, allows to significantly reduce the likelihood of dangerous vibrations and helps, if necessary, to find the fastest and most reliable ways to eliminate them during the engine debugging. At present, theoretical research is underway aimed at developing methods for calculating the possible level of dynamic stresses in the main parts of a gas turbine engine (GTE). However, the introduction of such calculations into design practice is hampered by the impossibility of a sufficiently accurate assessment of both disturbing forces and vibration damping forces.
The choice of parameters of a waterjet for ships
Authors:   St. Petersburg State Marine Technical University, St. Petersburg, Russia, Pogodin Yu.M. , Sadzhenitsa V.S. ,   A one-dimensional mathematical model of the working process of a waterjet work out, taking into account the influence of the input and output channels. A method for calculating the main parameters of a waterjet has been developed. The model of the axial pump was tested.
Published: January 2022

A one-dimensional mathematical model of the working process of a waterjet work out, taking into account the influence of the input and output channels. A method for calculating the main parameters of a waterjet has been developed. The model of the axial pump was tested.
Improving the pollutant removal system from the flow path of the axial compressor of a gas turbine plant
Authors:   St. Petersburg State Marine Technical University, St. Petersburg, Russia, Smirnov A.A. , Bogov I.A. ,   St. Petersburg State Marine Technical University, St. Petersburg, Russia, Tolmachev V.V. ,   St. Petersburg State Marine Technical University, St. Petersburg, Russia, Bezukhov A.P. ,   St. Petersburg State Marine Technical University, St. Petersburg, Russia, Fedorovtsev A.A. ,   St. Petersburg State Marine Technical University, St. Petersburg, Russia, Mitrofanov V.A. ,   Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russia, Sukhanov V.A. ,   Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russia
Published: January 2022

The information about the pollutants in the flow part of the axial compressor (AC) and the methods of their removal are considered. A new way of removing these pollutants is proposed and recommendations for its implementation are given.
Spatial Analysis of the CO Emission from Nineveh Governorate Using Remote Sensing Techniques and GIS
Authors: Ali Sabah H. , Najemaden Mohamed A.
Published: January 2022

Carbon Monoxide (CO) has a significant indirect effect on greenhouse gasses due to its ozone and carbon dioxide precursor, and its mechanism of degradation involving the hydroxyl radical (OH) which control the oxidizing ability of the tropospheric. To understand the effect of human activities on atmospheric composition, accurate estimates of the sources of atmospheric carbon monoxide (CO) are necessary. MOPITT (Measurements of Pollution in the Troposphere) is a NASA Terra satellite instrument designed to allow both Thermal-Infra-Red (TIR) and Near-Infra-Red (NIR) observations to be used to collect vertical CO profiles in the Troposphere via the concept of correlation spectroscopy. The objective of the current study is to analyze and map the monthly, seasonal and annual trend of CO concentration for year 2016 in Nineveh governorate using the retrieved CO Surface Mixing Ratio Day mode of level 3, version 7 dataset. The dataset was downloaded from the National Aeronautics and Space Administration (NASA) operated GIOVANNI portal. The results of dataset analysis in GIS software showed many sources of carbon monoxide in Nineveh Governorate, which change with months and seasons of the year. Generally, the observed CO concentration levels in the southern and western of the governorate were more than in the northern and eastern parts. The annually average CO ranges from (115.374 ppbv) to (132.452 ppbv). Also, CO emissions and concentrations were higher in winter (128.638-157.567 ppbv) than summer season (97.144-106.515 ppbv).
Tekoäly ja tieteelliset kirjastot
Authors: Ala-Kyyny Juuso
Published: January 2022

Tekoälyn ja sen keskeisen osa-alueen, koneoppimisen, historia juontaa vuosikymmenien taakse. Hypetermi tekoälystä on tullut viimeisen kymmenen vuoden aikana, kun laskentatehon kasvamisen myötä tekoälyn kehitystyö on laajentunut voimakkaasti.
Ketahanan Batang Kelapa Sawit Diimpregnasi Resin Pinus dan Serbuk Kayu Surian Terhadap Rayap dan Cuaca
Authors: Adjani Jessica Gita , Hadiyane Anne , Karliati Tati , Darwis Atmawi , Mukhsin Viona Febrinisa
Published: January 2022

The Resistance of Pine Resin and Surian Wood Sawdust Impregnated Oil Palm Stem Against Termite and WeatheringAbstractImpregnation substances into the oil palm trunks are one way to improve the oil palm trunk quality. This paper studies the optimum formulation of oil palm trunk impregnanted pine resin and Surian sawdust against dry-wood and subterranean termites as well as weathering performance. Impregnant concentration variations were mixtures of Tusam resin and Surian wood sawdust of 0% (RS0), 4% (RS1), 6% (RS2), and 8% (RS3) with three replications. Dry-wood termite test, subterranean termite test, and weather resistance test were carried out for 12 weeks of observation. The results showed that RS3 treatments were the optimum formulation of impregnated material used for oil palm trunk based on its resistance against dry-wood and subterranean termites resistance, while RS0 treatments were the optimum formula for weathering performances.Keywords: impregnation, oil palm trunk, pine resin, sawdust, Surian woodAbstrakSalah satu upaya untuk meningkatkan kualitas batang kelapa sawit adalah melalui impregnasi dengan resin pinus dan serbuk kayu Surian. Penelitian ini bertujuan untuk menentukan formulasi optimum impregnan batang kelapa sawit terhadap serangan rayap kayu kering dan rayap tanah serta ketahanan terhadap cuaca. Variasi konsentrasi impregnan yang digunakan yaitu campuran resin pinus dan serbuk kayu Surian 0% (RS0), 4% (RS1), 6% (RS2), dan 8% (RS3). Uji ketahanan rayap kayu kering, uji rayap tanah, dan uji ketahanan terhadap cuaca dilakukan selama 12 minggu pengamatan. Hasil penelitian menunjukkan bahwa konsentrasi optimum bahan impregnan batang kelapa sawit terimpregnasi terhadap ketahanan rayap kayu kering dan rayap tanah adalah formula RS3, sedangkan formulasi impregnan ketahanan cuaca optimum adalah batang kelapa sawit dengan formula RS0.Kata kunci: impregnasi, batang kelapa sawit, resin pinus, serbuk kayu, kayu Surian
Historical and Informational Potential of the University Libraries Websites
Authors: Yudina Inna G. , Bazyleva Elena A.
Published: January 2022

Historically, the scientific library has always been an important component of the structure of higher educational institution in Russia. Development of new technologies, creation of electronic information environment and availability of universities websites imposes on libraries certain responsibilities, associated not only with the provision of electronic resources and services to users, but also with the reflection on websites of various information about the libraries themselves, in particular, regarding their history. This information not only affects the formation of libraryʼs image, but can also become the basis for conducting modern scientific research in the field of library science. The presented research is devoted to studying the reflection of the history of libraries in the web space and determining the main trends in the development of information resources based on information on the history of librarianship.

The authors highlight the results of the analysis of content of the libraries websites of the universities subordinate to the Ministry of Science and Higher Education of the Russian Federation. The paper presents the data obtained upon the study of websites (web pages) of 252 universities and their libraries. The study was conducted from February to April 2021. There authors identified five options for the representation of materials on the history of librarianship: historical reference, historical essay, comprehensive information product, presentation in Microsoft PowerPoint, multimedia video presentation. Historical reference is the most common of them is. Based on the dates of establishment of universities and libraries compared in the course of study, it was possible to present in dynamics the general picture of their development.
Digital Networks and Suggestions in the Fabric of Virtual Communications
Authors: Yaroslavtseva Elena I.
Published: January 2022

Trends related to the development of digital technologies and their impact on the social and humanitarian sphere continue to be relevant. The emergence of digital networks not only leads to the expansion of social connections, but also forms the trend of transformation of digital networks into augmented reality, which displaces the living space of nature from the lives of young generations. Deepening of the transformations carries certain risks, since it becomes a source of generating cyber reality, an environment of unpredictable communications. It escapes attention that techno-networks, created initially for the transmission of formalized information flows, are beginning to be mastered by a person for a new type of resources as a space of intersubjective communication. As a result, due to the lack of the necessary cultural field, a qualitatively different, surrogate interaction develops. Under these conditions, the simplest communication models are implemented, based solely on the personal psychological experience of each of the participants, who hide in the digital world from the complexities of real life. For a modern person, the web becomes a space of illusory openness, a zone of serious risks and qualitative changes. The article examines how quickly each member of society gets involved in the new, digital format of interaction and hi-tech communications, and how this practice determines the person’s perception of the world, their cognitive activity. Essentially, it is necessary to clarify how the “web” or “net” space has created the prospects for the development of a real person, carrying a natural potential, and how high the psychological risks of imprinting, suggestive suppression of creative forces in the new topos of communications are. It is also important to raise the issue of formulating expert assessments of the development of networks for humans. Is it possible to consider today’s issues as a natural stage in overcoming the problems of self-realization of a person’s creative potential, or is this due to the fact that in a digital network a person develops not as an autopoetic integrity, but as a being partially prosthetic in audio-video format? Such specific activity impose restrictions on the process of cognition of the world by a person, on their worldview, and affect their independence and behavior. It is important to understand whether a human-sized network adequate to the person’s complexity is possible, and how the modern social environment, human culture, can be enriched with the network potential, new communications.
Pekanbaru City Snack E-Commerce Application Design Based on Android
Authors: Setiawan Panji Rachmat , Ardiansyah Ardiansyah
Published: January 2022

E-Commerce is a concept that quite developed in the field of information technology. E-Commerce gives more convenience and advantages when compared with conventional, including all the information needed by cunsomers can be accessed more detail, without being limited with place and time, and transactions process can be done much easier. So that the implementation of this system will make it easier and more profitable for many parties, both consumers and sellers. This development method in building E-Commerce application is based on the theory of the Waterfall Model. Waterfall is a software development methodology, which proposes an approach to systematic and sequential software which starts at the system progress level throughout the analysis, design, code, testing and maintenance. The purpose of this research is to produce Pekanbaru city snack E-Commerce application based on android. By implementing this system will make it easier and more profitable for many parties, both consumers and sellers.
Personal safety of young school children as a sphere of educational activities
Authors: Борисова Т.С. , Берлянд Ю.Б. , Снидко А.А.
Published: January 2022

Потребность в эффективном механизме обеспечения личной безопасности детей актуальна всвязи с ростом угроз их безопасной жизнедеятельности, ростом числа преступных деяний противполовой неприкосновенности, в том числе совершенных посредством сети Интернет, массовыминарушениями прав несовершеннолетних, касающихся преступного поведения в отношении ребенка.Актуализировались проблемы защиты несовершеннолетних от посягательств на их свободу, половуюнеприкосновенность, психическое и физическое здоровье, в том числе в социальном сегменте сетиИнтернет. Актуализировалась проблема пересмотра профилактической работы по обеспечению личнойбезопасности несовершеннолетних, формирования навыков безопасного поведения у детей младшегошкольного возраста в различных сферах воспитательной деятельности. Новизна нашего подхода ванализе научного дискурса проблем личной безопасности детей, случаев преступлений против половойнеприкосновенности несовершеннолетних, в предложенных рекомендациях как выстраивать процессформирования безопасного поведения детей младшего школьного возраста как сферы воспитательнойдеятельности, как возможности защиты от посягательств на жизнь, здоровье (физическое ипсихическое), свободу и половую неприкосновенность детей, как воспитательный феномен,обеспечивающий формирование у детей знаний, умений и навыков безопасной жизнедеятельности.Основным направлением формирования личной безопасности детей младшего школьного возраставыступает обучение и воспитание во взаимодействии со всеми субъектами образовательнойдеятельности.

The need for an effective mechanism to ensure the personal safety of children is relevant due to thegrowing threats to their safe life, the increase in the number of criminal acts against sexual integrity, includingthose committed via the Internet, massive violations of the rights of minors concerning criminal behavior againsta child. The problems of protecting minors from attacks on their freedom, sexual integrity, mental and physicalhealth, including in the social segment of the Internet, have been actualized. The problem of revising preventivework to ensure the personal safety of minors, the formation of safe behavior skills in children of primary schoolage in various fields of educational activity was actualized. The novelty of our approach is in the analysis of thescientific discourse on the problems of personal safety of children, cases of crimes against the sexual integrityof minors, in the proposed recommendations on how to build the process of forming safe behavior of primaryschool children as a sphere of educational activity, as an opportunity to protect against attacks on the life, health(physical and mental), freedom and sexual integrity of children, as an educational phenomenon that ensures theformation of knowledge, skills and skills of safe life in children. The main direction of the formation of the personalsafety of children of primary school age is education and upbringing in interaction with all subjects of educationalactivity.
Pedagogical development of improving the methodological work of medical workers in a pandemic
Authors: Введенская И.П. , Введенский В.Ю. , Чуйкова О.А.
Published: January 2022

В статье рассматривается проблема труда медицинских работников службы экстренноймедицинской помощи в период пандемии COVID-19. В статье автор приходит к выводу, что в условияхвспышки COVID-19 многим медицинским работникам приходится справляться с тяжёлойдополнительной нагрузкой, долгое время оставаясь на работе и лишаясь отдыха. При этомчрезвычайная ситуация с пандемией могла вызвать стрессовые условия работы для медицинскихработников по разным причинам, учитывая их внезапный перевод на другие должностные места в связис возрастной уязвимостью к вирусу или новые незнакомые задачи и работу в условиях повышеннойнагрузки. Частота вспышек заболеваний увеличилась за последнее столетие из-за роста населения,возросшей взаимосвязанности мира, микробной адаптации и изменений, экономического развития,изменений в землепользовании и изменения климата. К новым инфекционным заболеваниям, которыевызвали эпидемии за последние два десятилетия, относятся тяжелый острый респираторный синдром(SARS) в 2003 году, вирус гриппа A подтипа H1N1 в 2009 году, коронавирус ближневосточногореспираторного синдрома (MERS-COV) в 2012 году, болезнь, вызванная вирусом Эбола (EVD) в 2014 г.,вирус гриппа A подтипа H7N9 и коронавирус тяжелого острого респираторного синдрома 2 (SARS-CoV-2) в декабре 2019 г., что привело к пандемии коронавирусного заболевания 2019 г. (COVID-19).

The article deals with the problem of the work of medical workers of the emergency medical serviceduring the COVID-19 pandemic. In the article, the author comes to the conclusion that in the conditions of theCOVID-19 outbreak, many medical workers have to cope with a heavy additional load, staying at work for a longtime and losing rest. At the same time, an emergency situation with a pandemic could cause stressful workingconditions for medical workers for various reasons, given their sudden transfer to other positions due to agevulnerability to the virus or new unfamiliar tasks and work in conditions of increased workload. The frequency ofdisease outbreaks has increased over the last century due to population growth, the increasedinterconnectedness of the world, microbial adaptation and change, economic development, land use changesand climate change. To new infectious diseases that caused epidemics in the past two decades include thesevere acute respiratory syndrome (SARS) in 2003, influenza a subtype H1N1 in 2009, middle East respiratorysyndrome coronavirus (MERS-COV) in 2012, the disease caused by the Ebola virus disease (EVD) in 2014,influenza a subtype H7N9 and coronavirus severe acute respiratory syndrome 2 (SARS-CoV-2) in December2019, which led to the pandemic of coronavirus disease 2019 (COVID-19).
Prevention of psychoemotional burnout among employees of the UIS by dosed physical exertion
Authors: Перфильев А.А.
Published: January 2022

Представленная статья посвящена актуальной проблеме профессиональногопсихоэмоционального выгорания сотрудников уголовно-исполнительной системы. Автор использует всвоей статье метод составления причинно-следственных связей, сначала описывая стресс, какфизиологическое явление, а затем те последствия, к которым приводит продолжительный стресс. Такжеавтором используется метод исторического анализа: рассматривается история возникновенияэмоционального выгорания, основные его симптомы, согласно теории, которая была выдвинутаосновоположником. Проводятся параллели с наиболее известными трудами отечественныхисследователей данного психологического состояния. Также в статье автор рассматривает основныепути борьбы с выгоранием и методы профилактики с точки зрения физиологии человеческого организма.В статье приводятся весомые аргументы, описывающие положительное влияние дозированныхфизических нагрузок на эмоциональное состояние человека с точки зрения его физиологии. Наосновании полученных данных были составлены рекомендации по выполнению ряда физическихупражнений для улучшения своего психического состояния. Статья ориентирована на конкретнуюсоциальную группу – сотрудников уголовно-исполнительной системы. Проблема выгорания в данномслучае рассматривается в связи со спецификой профессии. Статья рекомендована широкому кругучитателей: курсантам, действующим сотрудникам, работникам.

The presented article is devoted to the actual problem of professional psycho-emotional burnout ofemployees of the penal system. The author uses in his article the method of making causal relationships, firstdescribing stress as a physiological phenomenon, and then the consequences that prolonged stress leads to.The author also uses the method of historical analysis: the history of the occurrence of emotional burnout, itsmain symptoms are considered, according to the theory that was put forward by the founder. Parallels are drawnwith the most famous works of domestic researchers of this psychological state. Also in the article, the authorexamines the main ways to combat burnout and prevention methods from the point of view of the physiology ofthe human body. The article presents weighty arguments describing the positive effect of dosed physical activityon the emotional state of a person from the point of view of his physiology. Based on the data obtained,recommendations were made for performing a number of physical exercises to improve their mental state. Thearticle is focused on a specific social group - employees of the penal enforcement system. The problem ofburnout in this case is considered in connection with the specifics of the profession. The article is recommendedto a wide range of readers: cadets, current employees, employees.
Legal aspects of the pedagogical process for the legal education of older preschool children
Authors: Алексеев С.Г.
Published: January 2022

В статье рассматривается актуальность развития правовых аспектов педагогического процессав решении задач дошкольного правового воспитания. Необходимость развития компетентностипедагогов, в области дошкольного правового воспитания, обоснована важностью реализациитребований, определенных Федеральным государственным образовательным стандартом дошкольногообразования, в области правового воспитания и социального воспитания ребенка. Автор определилструктуру компетентности педагогов в области дошкольного правового образования, представилхарактеристики компонентов, описал уровни их сформированности. Предложена модель развитияпедагогического процесса в области дошкольного правового образования, раскрыты педагогическиеусловия ее реализации. Приведены примеры рекомендуемых форм и методов развития педагогическогопроцесса в области дошкольного правового образования, которые могут быть реализованы вдошкольной образовательной организации.

The article considers the relevance of the development of legal aspects of the pedagogical process insolving the problems of preschool legal education. The need to develop the competence of teachers in the fieldof preschool legal education is justified by the importance of implementing the requirements defined by theFederal State Educational Standard of Preschool Education in the field of legal education and social educationof a child. The author defined the structure of teachers' competence in the field of preschool legal education,presented the characteristics of the components, described the levels of their formation. A model of thedevelopment of the pedagogical process in the field of preschool legal education is proposed, the pedagogicalconditions for its implementation are disclosed. Examples of recommended forms and methods of developmentof the pedagogical process in the field of preschool legal education, which can be implemented in a preschooleducational organization, are given.
Extracurricular work with teenagers in the mid-1950s - mid-1960s (on the example of the city of Orenburg)
Authors: Торшина А.В.
Published: January 2022

В статье на примере города Оренбурга охарактеризована внешкольная работа с подростками всередине 1950-х – середине 1960-х годов. Подчеркивается, что в процесс воспитания активно включеныпроизводственные коллективы базовых и шефствующих предприятий. Развиваются молодежные клубы,клубы выходного дня, клубы юных краеведов, клубы веселых и находчивых, клубы юных художников.Середина 1950-х - 1960-х годов - время в истории России, связанное с именем Никиты СергеевичаХрущева. Реформы данного периода охватили не только политику, экономику, культуру, но иобразование и науку. Название реформам дала повесть Ильи Эренбурга «оттепель». Данный периодхарактеризуется свободой жизни, возможностью самовыражения, честным творчеством. Особенностиисторического периода отразились на деятельности внешкольных учреждений Оренбурга, в центревнимания которых: интерес ребенка, его деятельность в коллективе; демонстрация обучающемусязначимости его знаний и умений для коллектива; учет успехов ребенка; обмен информацией междувнешкольным учреждением и школой об участниках творческих коллективов. В связи с этим, воспитаниеподрастающего поколения во внешкольных учреждениях начинает приобретать «деятельностный»характер. Развивается методика коллективного творческого дела И.П. Иванова.

The article describes extracurricular work with teenagers in the mid-1950s – mid-1960s using theexample of the city of Orenburg. It is emphasized that the production teams of basic and patronizing enterprisesare actively involved in the process of education. Youth clubs, weekend clubs, clubs of young local historians,clubs of the cheerful and resourceful, clubs of young artists are developing. The mid-1950s - 1960s is a time inthe history of Russia associated with the name of Nikita Sergeyevich Khrushchev. The reforms of this periodcovered not only politics, economics, culture, but also education and science. The name of the reforms wasgiven by Ilya Ehrenburg's novel "thaw". This period is characterized by freedom of life, the possibility of selfexpression,honest creativity. The peculiarities of the historical period were reflected in the activities of out-ofschoolinstitutions in Orenburg, which focus on: the interest of the child, his activities in the team; demonstratingto the student the importance of his knowledge and skills for the team; taking into account the success of thechild; exchange of information between the out-of-school institution and the school about the participants ofcreative teams. In this regard, the upbringing of the younger generation in extracurricular institutions is beginningto acquire an "activity" character. The methodology of I.P. Ivanov's collective creative work is being developed.
A Cybernetic Chemical Robot for Exploration and Optimisation of Nanomaterials
Authors: Cronin Leroy , Jiang Yibin , Salley Daniel , Sharma Abhishek , Keenan Graham , Mullin Margaret
Published: January 2022

We present a cyber-physical robot for the exploration, discovery, and optimisation of nanostructures which is driven by real-time spectroscopic feedback, theory and machine learning algorithms that control the reaction conditions and allow the selective templating of the reactions. This approach allows the transfer of materials as seeds, as well as digital information, between cycles of exploration, opening the search space like gene transfer in biology. The open-ended exploration of the seed-mediated multistep synthesis of gold nanoparticles (AuNPs) via in-line UV-Vis characterisation led to the discovery of five classes of nanoparticles by only needing to perform ca. one thousand from a total of ca. >1023 possible experiments. The platform optimises the nanostructures with desired optical properties by combing experiments and scattering simulations to achieve a yield of up to 95% and the synthesis code is outputted in a universal format using Chemical Description Language(χDL) together with the analytical data to produce a unique digital signature to aid and confirm that the synthesis is universally reproducible.
Supramolecular imaging agents targeting cancer biomarkers
Authors: d'Orchymont Faustine , Holland Jason P.
Published: January 2022

Mechanically interlocked molecules present opportunities to construct therapeutic drugs and diagnostic imaging agents but harnessing supramolecular chemistry to make biologically active molecules in water is a challenge. Here, we describe a rotaxane-based approach in the synthesis of radiolabelled proteins and peptides for molecular imaging of cancer-specific biomarkers in vivo. Host-guest chemistry with mono-functionalised beta-cyclodextrin, combined with curcurbit[6]uril catalysed cooperative capture synthesis, produced radioactive gallium-68 or zirconium-89-labelled metallo[4]rotaxanes. Simultaneous, one-pot radiolabelling and photochemical conjugation to monoclonal antibodies produced a viable radiotracer that was evaluated in vivo for quantitative positron emission tomography (PET) imaging of cancer biomarker expression. The rotaxane architecture can be easily tuned to accommodate different radioactive metal ion complexes, other proteins and peptide-based drugs, and fluorophores for optical detection. This technology provides a future platform to explore the use of mechanical bonding to optimise drug delivery, control metabolism and excretion profiles, and enhance the efficacy of tumour specific agents.
Late acne in women: patients of gynecologists, endocrinologists or dermatologists?
Authors: Golousenko Igor Yu.
Published: January 2022

The article raises the problem of late acne in women. As a result of observation of 326 patients aged 20 to 40 years, evaluation of the data of a significant number of laboratory and instrumental tests, it was found that 257 (79%) women had hyperandrogenism of various etiologies. On the basis of which, 6 groups of patients were identified, which allows applying etiological treatment. It is concluded that only the cooperation of dermatovenerologists, gynecologists, endocrinologists can help an increasing number of such patients.
Artificial intelligence: how it works and criteria for assessment
Authors: Shlivko Irena L. , Garanina Oxana Ye. , Klemenova Irina A. , Uskova Kseniia A. , Mironycheva Anna M. , Dardyk Veniamin I. , Laskov Viktor N.
Published: January 2022

Artificial intelligence is a term used to describe computer technology in the modeling of intelligent behavior and critical thinking comparable to that of humans. To date, some of the first areas of medicine to be influenced by advances in artificial intelligence technologies will be those most dependent on imaging. These include ophthalmology, radiology, and dermatology. In connection with the emergence of numerous medical applications, scientists have formulated criteria for their assessment. This list included: clinical validation, regular application updates, functional focus, cost, availability of an information block for specialists and patients, compliance with the conditions of government regulation, and registration. One of the applications that meet all the requirements is the ProRodinki software package, developed for use by patients and specialists in the Russian Federation. Taking into account a widespread and rapidly developing competitive environment, it is necessary to soberly treat the resources of such applications, not exaggerating their capabilities and not considering them as a substitute for a specialist.
Public understanding of climate change and support for mitigation
Authors:   ESRI, timmons shane , lunn pete
Published: January 2022

In this study, a large, representative sample of the Irish population undertook a multiple-choice quiz about climate change. The 10-minute quiz was designed to engage participants and to measure their understanding, not of facts and figures, but of the scientific relationships behind climate change – of what causes what, and how. The study was conducted in mid-October 2021. As well as revealing how well the population understands climate change, the central focus of the study was the relationship between understanding and willingness to act. To investigate this, the study contained an experiment that tested whether exposing people to the answers to the quiz questions altered their attitudes to climate policy and individual behaviour. Half the sample was randomly assigned to see the answers to the quiz questions, while the other half was not.We then measured support for climate mitigation policy (in particular, a carbon tax) and judgements of individual behaviour. In this way, we conducted an experimental test of whether engaging with accurate scientific information about climate change has an impact on willingness to tackle it.
STAND STRUCTURE AND PRODUCTIVITY OF THE FIREFLY RIVERINE MANGROVE HABITAT AT THREE RIVERS IN PENINSULAR MALAYSIA
Authors: Nur-Fatehah SR , Nur-Shafikah I , Shamsul K , Wan-Juliana WA , Norela Sulaiman  , Shahril MH , Nurul-Darsani AD
Published: January 2022

Studies on floristic composition, forest structure and tree diversity are important to determine the pattern of stand structure, current status and floristic variation of firefly riverine mangrove habitats in Peninsular Malaysia. Thus, this study was conducted in three rivers, namely Sungai Chukai, Terengganu, Sungai Rembau-Linggi, Negeri Sembilan and Sungai Sepetang, Taiping, Perak. A total of 647,362 and 514 tree stands measuring 1 cm diameter and above were enumerated in 0.5 ha plots at the three sites, respectively. A total of 40 species were recorded in Sungai Chukai, 17 species in Sungai Rembau-Linggi and 14 species in Sungai Sepetang. The 0.5, 0.35 and 0.40 ha of each study site, respectively, were capable of capturing all the species in the mangrove forest. Rhizophoraceae family was found to have the highest density and basal area in all the study sites. The highest species density for Sungai Chukai, Sungai Rembau-Linggi and Sungai Sepetang was R. apiculata with a density of 262 ind ha-1, 120 ind ha-1 and 516 ind ha-1, respectively. The major contributor of total basal area at Sungai Chukai, Sungai Rembau-Linggi and Sungai Sepetang were X. granatum (5.5583 m2 ha-1) and R. apiculata with 10.6833 m2 ha-1 and 11.7491 m2 ha-1, respectively. Diversity and species richness were higher at Sungai Chukai (H’= 2.82, R’= 6.03) compared to Sungai Rembau-Linggi (H’=2.09, R’= 2.72) and Sungai Sepetang (H’=1.43, R’= 2.08). The highest total biomass of mangrove forest was at Sungai Rembau-Linggi with 321.21 t ha-1 followed by Sungai Sepetang (247.41 t ha-1) and Sungai Chukai (210.36 t ha-1). These results indicated that the current status of community structure and vegetation varied among the rivers. The study can act as a guideline in the management plan of firefly habitats, which also affect firefly distribution along the three rivers in Peninsular Malaysia.
EFFECT OF GENETIC GAIN IN DIAMETER AND WOOD DENSITY ON ADVANCED GENERATION BREEDING STRATEGY OF ACACIA MANGIUM IN INDONESIA
Authors: Sunarti S , Nirsatmanto A , Brawner J , Setyaji T , Kartikaningtyas D , Handayani BR , Surip  , Hidayati F
Published: January 2022

Breeding of Acacia mangium in Indonesia was initially focused on selection for improving growth and stem form. Changes in wood density which resulted from selection for improved growth was impacted by adverse correlation between the both traits. This study aimed to quantify genetic gain in the diameter and wood density from two A. mangium breeding generations and to use this information in developing breeding strategy to improve both traits simultaneously. Materials were obtained from 4.5-year-old trees in a progeny trial consisting of families from first (F-1) and second (F-2) generations along with infused families (F-0) as control. Genetic gain was calculated as the percent increase in diameter and wood density from F-1 and F-2 over the control. Diameter and wood density from F-1 and F-2 were higher than F-0. Genetic gains for diameter increased from 3.7% in F-1 to 7.0% in F-2. Conversely, gain for wood density decreased from 1.9% in F-1 to 0.3% in F-2. Correlations between diameter and wood density varied from weak to moderate along the stem sections. The results imply a combined approach incorporating selection for diameter and wood density in mixed-breeding generations will provide simultaneous improvement in both traits.
Capa
Authors: História da Mídia Associação Brasileira De Pesquisadores de
Published: January 2022

Capa
Weaving Worlds: Raranga, whakapapa, and mana wahine
Authors:   , Shaw Selena
Published: January 2022

The focus of this project is to explore female Indigenous design knowledge in the context of raranga harakeke, or flax weaving, and I situate this rangahau and kōrero in the experiences of my own whānau of weavers. There is the voice of my own experience and mastery, and there are the voices of my tīpuna who continue to guide and, at times, lead my understandings.
Development and Application of Workbook Teaching Materials – Taking the Curriculum Construction of Pharmacy and Traditional Chinese Medicine Pharmacy in Higher Vocational Colleges of Pharmaceutical Specialty Group as an Example
Authors: Chen Jianwen , Yang Jianbing
Published: January 2022

In higher vocational colleges, professional construction is the core, curriculum construction is the basis of professional construction, and textbook construction is the support for curriculum construction. The quality of textbooks directly affects the quality of curriculum construction. Curriculum construction and professional construction are linked. In this article, the three major courses of drug operation and management are reconstructed, the content structure is reorganized, the ability points guided by work tasks are screened, and the development of loose leaf work manual teaching materials is explored in order to ensure that curriculum construction would serve professional construction as well as achieve the real goal of cultivating compound talents with technical skills and innovation in higher vocational colleges.
Implementing Aesthetic Education in the Teaching of Chinese Language and Literature
Authors: Yan Peng
Published: January 2022

Chinese language and literature is an essential subject in colleges as it shoulders an important responsibility in maintaining quality education and imparting elements of humanities to students. The approach of aesthetic education in this discipline is not only the actual demand for quality education in colleges and universities and the all-round development of students in the new era, but also an important way to cultivate the attributes of the discipline itself and students’ ability of aesthetic taste. It is the treasure of China’s traditional culture and plays an important carrier as well as role in inheriting excellent culture. Using the approach of aesthetic education in the teaching of Chinese language and literature is the focus of educators. Therefore, this article analyzes the strategies of implementing aesthetic education in the teaching of Chinese language and literature and provides a reference basis for the implementation of aesthetic education in this discipline.