bluuebunny/crossref_metadata_2025 huggingface dataset:
From Ethical Aspects of Literature to Literary Historical Studies in an Intercultural Context
Authors: Mezeg Adriana , Žigon Tanja , Kramberger Petra
Published: December 2023

In recent years, we have conducted research in various areas within the framework of the research programme Intercultural Literary Studies (No. P6-0265), especially on ethical aspects in literature, on the role and significance of translation as an intercultural mediation, on the literary-historical aspects of interculturality, and on the didactics of literature and translation. In the second part of this year’s double issue of Acta Neophilologica we present the latest findings of the researchers who make up the Intercultural Literary Studies programme group, and we have also invited colleagues from other programme groups as well as two colleagues from abroad.
Feeding habits and diet composition of Octopus cyanea (Gray, 1849) in Zanzibar waters, Tanzania
Authors: Hamad Amini I. , A. Muhando Christopher
Published: December 2023

The octopus fishery in Zanzibar is an essential activity of coastal communities. To assist with developing fisheries management plans, baseline information on the feeding of Octopus cyanea (Gray, 1849) was collected in relation to sex and maturity stages. The feeding habits and diet composition of 543 O. cyanea were studied over a period of 12 months at Paje, Kizimkazi, Chwaka Bay and Nungwi. Samples at each site were collected on two days per month during spring tide. Digestive tract contents revealed that O. cyanea preyed on 36 species of crustaceans, molluscs and fishes, with crabs a major prey item. The number of prey species in a single stomach ranged from one to six. O. cyanea in Zanzibar is therefore a generalist predator with a mixed diet. The octopus gonadosomatic index (GSI) indicated a peak breeding season in June to October, which correlated with low prey consumption. Mature octopuses ingested a small amount of food from mainly small sessile prey. Females consumed less food than males of similar maturity stages, suggesting that they ate less or had higher digestion rates. The information is useful for developing fisheries management plans for the octopus fishery in Zanzibar.
The lifestyle of the leopard gecko and the importance of ultraviolet radiation, vitamin D and calcium
Authors: Franco Francisco L. , Oliveira Paula A. , Patrício Rui , Faustino-Rocha Ana I.
Published: December 2023

The gecko leopard (Eublepharis macularius) was first described in 1854 by British herpetologist Edward Blyth. It is one of the most popular pet lizard species, due to its docile temperament, ease of maintenance and reproduction in captivity, its high longevity and small size, and its beauty and diversity of colours and patterns. Ultraviolet (UV) radiation is an important behavioural regulator. Vitamin D also regulates many fundamental physiological functions in vertebrates, mainly calcium homeostasis. Because of the great diversity of reptile species and the wide range of environmental adaptations, it is important to know the necessities and adaptations of each species regarding UV, vitamin D and calcium requirements. This study provides an overview of the leopard gecko’s lifestyle, and the importance of ultraviolet radiation, vitamin D and calcium for this species.
Microbiological quality of Livno cheese
Authors: Muftić Emina , Mušanović Anela , Fazlović Neira , Čaklovica Kenan , Smajlović Muhamed , Magoda Amina , Gradaščević Nedžad , Smajlović Ahmed , Članjak-Kudra Enida
Published: December 2023

This study aimed to assess the microbi- ological quality of Livno cheese and milk as its raw material. It also investigated potential differences in microorganism presence and quantity between milk and cheese to under- stand the impact of milk processing on micro- biological quality. A total of 15 raw milk and 15 Livno ripened cheese samples were ana- lysed for the presence of Salmonella spp. and Listeria monocytogenes. Detection and quan- tification were performed for the following microorganisms: coagulase-positive staphy- lococci, aerobic mesophilic bacteria (for milk samples), E. coli, Enterobacteriaceae, sulfite-re- ducing clostridia (for cheese samples), yeasts and moulds. Salmonella spp. was not detected in any of the samples. Microbiological analy- sis of milk revealed varying levels of aerobic mesophilic bacteria, E. coli, Enterobacteriaceae, yeasts, moulds, and L. monocytogenes. Coagu- lase-positive staphylococci were detected in only two of 15 raw milk samples. In 15 Livno cheese samples, all tested microorganisms were below detectable levels except for E. coli (found in two samples) and Enterobacteriaceae (found in three samples). Statistical tests indi- cated significant differences in microbial pres- ence and quantity between milk and cheese, except for coagulase-positive staphylococci. Given the importance of cheese microbiology for food safety and consumer health, this re- search provides valuable insights into the pro- duction and quality control of this traditional Bosnian cheese.
Use of the arts in pharmacy education to develop self-perceived empathy
Authors: Allinson Maria , Archer Neil , Montero-Diaz Fiorella , Jacklin Simon , Thompson Jessica
Published: December 2023

Background: Demonstrating empathy is a key competency expected of pharmacy undergraduate students. Various art media have been shown to help develop empathy in students. A new optional module designed to incorporate a range of art forms to support empathy development has been delivered and evaluated in a UK School of Pharmacy. The aim of this paper is to present this module and its evaluation.
Methods: A standard teaching evaluation was emailed to students at the end of the module, and reflective work submitted as part of the assessment was thematically analysed in this mixed methods study. Ethics approval was obtained from Keele University to undertake the study.
Results: Eleven students were assigned to the module. The teaching evaluation was completed by ten students and was rated favourably in every respect. This positive viewpoint was supported by analysis of eleven reflective pieces. Four key themes emerged from the data, namely, i) the learning experience; ii) the perception of illness; iii) seeing the patient as an individual; and iv) perceived empathy development.
Conclusion: This study describes a range of artistic activities that can increase perceived empathy levels and be enjoyed by students. Further research is necessary to ascertain if this self-perceived empathy results in increased levels in practice.
State Formation from Below
Authors: Nickel Carsten
Published: December 2023

In late-nineteenth century Germany, the new public services required under rapid industrialization could not be provided in a top-down manner, despite Bismarck’s authoritarian aspirations. Lower-level actors therefore pushed for an alternative — well-established during centuries of internal state formation — based on the principle of subsidiarity (Latin for “assistance”): the coordination of mutual assistance, from local auxiliary funds to new electoral systems. The article theorizes the initially ecclesial programme of subsidiarity in the terms of modern politics and economics, and proposes a five-stage model for the rise of coordinated institutions from the private to the public level in late nineteenth-century Germany, based on an analysis of historical sources.
Optimizing Performance: A Deep Dive into Overall Equipment Effectiveness (OEE) for Operational Excellence
Authors: Ullah Md Rahamat , Molla Selim , Siddique Iqtiar Md , Siddique Anamika Ahmed , Abedin Md. Minhajul
Published: December 2023

This paper delves into the pivotal role of Overall Equipment Effectiveness (OEE) as a crucial performance measurement tool for enhancing operational efficiency. OEE is a comprehensive metric that assesses the utilization of equipment, availability, performance, and quality to provide a holistic view of operational performance. By thoroughly analyzing OEE and practically applying its principles, organizations can unlock significant opportunities to optimize their operational processes. The study begins by elucidating the concept of OEE and its three core components: Availability, Functioning, and Attribute. A comprehensive analysis of each component is presented, highlighting the importance of measuring, and improving these aspects in any operational setting. Through practical case studies and real-world examples, this paper illustrates how organizations can harness the power of OEE to identify areas of improvement and implement targeted strategies for enhanced performance. It explores how OEE can uncover hidden losses, reduce downtime, and drive quality improvements, ultimately leading to increased productivity and profitability. Additionally, the paper discusses best practices for OEE implementation and measurement, emphasizing the importance of data collection, analysis, and continuous improvement. It also delves into the challenges and potential pitfalls that organizations may encounter when adopting OEE as a performance measurement tool.
Pengaruh Modernisasi Sistem Administrasi, Peraturan, Kesadaran, Sanksi Perpajakan Terhadap Kepatuhan Wajib Pajak Orang Pribadi Di Wilayah Kabupaten Sleman
Authors: Priyani Septi , As’ari Hasim
Published: December 2023

Penelitian ini bermaksud guna mengetahui pengaruh modernisasi sistem administrasi, Peraturan, Kesadaran, dan sanksi perpajakan terhadap kepatuhan wajib pajak orang pribadi di wilayah kabupaten Sleman tahun 2023. Karena jumlah individu dalam populasi tidak diketahui, maka digunakan non-probability sampling untuk pengumpulan sampel, dan purposive sampling digunakan untuk penentuan sampelnya dengan 99 responden. Metode kuesioner digunakan sebagai metode pengumpulan data. Sebelum dilakukan pembagian koesioner, agar diperoleh hasil yang sesuai dengan fakta, maka diperlukan uji coba instrumen guna diuji validitas serta reliabilitasnya. Teknik analisis data dikerjakan dengan uji asumsi klasik yakni uji heteroskedastisitas, uji multikolinearitas serta uji normalitas, sebagai syarat uji regresi dalam pengujian hipotesis. Uji koefisien korelasi dan uji koefisien  determinasi merupakan rangkaian uji hipotesis yang diterapkan pada penelitian ini. Temuan dari penelitian ini: Modernisasi sistem administrasi perpajakan serta peraturan perpajakan mempunyai pengaruh signifikan positif terkait kepatuhan wajib pajak orang pribadi yang bekerja di rumah sakit wilayah kabupaten Sleman, sedangkan Kesadaran perpajakan serta sanksi perpajakan tidak berdampak terhadap kepatuhan wajib pajak pajak orang pribadi yang bekerja di rumah sakit di wilayah kabupaten Sleman
PENGARUH PENERAPAN GOOD GOVERNANCE KOMPETENSI SUMBER DAYA MANUSIA TERHADAP KUALITAS PENGELOLAAN ADMINISTRASI KEUANGAN DAN BARANG
Authors: Wibowo Edi , Maidarti Titin , Nuswandari Inti
Published: December 2023

Tujuan penelitian ini yaitu: untuk menganalisis pengaruh dari penerapan good governance, dan kompetensi sumber daya manusia, terhadap kualitas pengelolaan administrasi Keuangan dan Barang Milik Negara Kementerian Kesehatan Republik Indonesia. Metode yang dipakai adalah kuantitatif dengan menggunakan asosiatif. Populasi dalam penelitian adalah 93 orang pegawai Biro Keuangan Dan Barang Milik Negara Kementerian Kesehatan, dan menggunakan teknik total sampling, sampel penelitian ini adalah 93 sampel. Analisis data dengan melakukan uji Regresi Linier Berganda. Hasil penelitian ini yaitu terdapat pengaruh Good Governance terhadap Kualitas Pengelolaan Administrasi. Terdapat pengaruh Kompetensi Sumber Daya Manusia terhadap Kualitas Pengelolaan Administrasi.
Expedientes para acreditación: la información de egresados y empleo del área económico-administrativa de la Universidad Autónoma de Nayarit
Authors: Estrada José Ramón Olivo , Torres Carmelina Montaño , Nava Bernabé Ríos , Ponce Sonia Tapia
Published: December 2023

En este trabajo se analiza desde los procesos de acreditación, la problemática que implica la ausencia de una base de datos estructurada, donde se acopie la información necesaria para solventar las exigencias de los organismos acreditadores; además se vincula lo anterior con el desarrollo del proyecto sobre el empleo de los profesionistas formados en nuestra universidad, y su percepción de sus trayectorias laborales y el desarrollo de las capacidades en la institución y los espacios de trabajo; este estudio da cuenta sobre la pertinencia como un factor central en la acreditación y la necesidad que se tiene para integrar y validar los proyectos de carácter institucional que están desarrollando investigadores, cuando se realizan esfuerzos en la construcción de instrumentos para recabar información ausente en la universidad. Considerando que solo con los procesos de acreditación, no se puede asegurar la real calidad o la pertinencia de la actividad académica validada en los diversos grupos sociales.
INTERTEXTUALITY AND INTERDISCURSIVITY IN POST-COLONIAL LANGUAGE POLICIES IN KENYA
Authors: Nganga Chege Samuel , Maroko Geoffrey , Ong’onda Anashia Nancy
Published: December 2023

Addressing the intricate challenges within the realm of language planning and policy involves establishing meaningful connections between language policy texts, discourse, and actual language practices. Moreover, navigating connections across diverse domains, contexts, levels, layers, and scales presents a formidable challenge. Therefore, this study endeavours to unravel intertextual connections as a means of comprehending language-policy texts in the Kenyan context. Focusing on post-colonial language policies in Kenya, this paper explores intertextuality and interdiscursivity. Employing Fairclough's (1992) Critical Discourse approach, this analysis explores how language policy documents undergo decontextualization from prior discourses (intertextuality) and examine their correlation with different generic chains (interdiscursivity). The study employs a qualitative research design, specifically historical and documentary analysis. The study's findings reveal that post-colonial language policies exhibit links to both pre-colonial and current policy documents, showcasing vertical and horizontal intertextuality. Additionally, these policies are linked to a myriad of past and present discourses, such as those related to culture and diversity (interdiscursivity). Notably, the analysis of intertextuality and interdiscursive discourse reveals revisions to language policy and tracks the shifts in discourses surrounding this policy over time. In conclusion, this study emphasises that the meaningful interpretation of intertextuality and interdiscursivity renders language policy texts significant. It is anticipated that this research will shed light on understanding language policy through the lens of intertextuality and interdiscursivity, contributing to a more comprehensive perspective on language policy dynamics.
 

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DYNAMIC RELATIONSHIPS: E-COMMERCE SALES AND KEY EXOGENOUS VARIABLES IN THE PHILIPPINES
Authors: Montano Vicente E. , Mercado Joanna Lynn L.
Published: December 2023

This study delves into the complex and evolving landscape of e-commerce in the Philippines, focusing on the relationship between E-Commerce Sales as the endogenous variable and a set of influential exogenous variables, including Digital Marketing Spending, GDP Growth, Internet Penetration, and Mobile Phone Ownership. This research employs a flexible spline modeling approach, uncovers non-linear associations, and offers significant implications for academic understanding and practical applications. The findings underscore the growing impact of Digital Marketing Spending on E-Commerce Sales, revealing the paramount role of online advertising and promotional strategies in the digital marketplace. Moreover, the study explains the intricate interplay between GDP Growth, Internet Penetration, Mobile Phone Ownership, and E-Commerce Sales, highlighting the non-linear nature of these relationships. As the Philippines continues its economic expansion and technological integration, these associations exhibit insightful implications for policymakers, businesses, and e-commerce stakeholders.
 

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FROM HO CHI MINH'S WORK “NEW LIFE” TO BUILD NEW RURAL RULES IN VIETNAM NOW
Authors: Danh Ngo Thanh
Published: December 2023

While leading the Vietnamese revolution, President Ho Chi Minh had many measures to direct and build new life to change the way of eating, dressing, living, and traveling in a scientific manner, civilized and progressive. His instructions are the basis for the Communist Party of Vietnam to set out policies and guidelines for cultural development in the people's national democratic revolution and the socialist revolution. In this article, the author mentions two essential contents: building a new life - the core contents; and the work of new life with new rural construction today.
 

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Spectral Properties of Discontinuous Boundary Value Problem with Transmission Conditions and Manypoint Singularities
Authors: BALTÜRK Tevhide , KANDEMİR Mustafa
Published: December 2023

In this study, we investigate a discontinuous Sturm-Liouville boundary value problem on three intervals

with manypoint-transmission conditions in direct sum of Sobolev space. We establish such spectral properties as Fredholmness and coreciveness with respect to the eigenvalue parameter
On the Semi-Analytical Solutions for the Kudryashov-Sinelshchikov Dynamical Equation Arising in Mixtures of Liquid and Gas Bubbles Without Neglecting of Heat Transfer and Viscosity
Authors: AYDIN Emre , ÇİLİNGİR SÜNGÜ İnci
Published: December 2023

In this study, Banach contraction method (BCM), Daftardar-Jafari method (DJM) and modified variational iteration method (MVIM) are proposed for the semi-analytical solutions of the Kudryashov-Sinelshchikov (K-S) dynamical equation. It has been shown that the analytical and semi-analytical solutions for the K-S dynamical equation with initial value problems by using semi-analytical methods can be obtained. In addition, the effectiveness and usefulness of the semi-analytical methods used are supported by tables and 3D figures. As the number of iteration or terms increases, how the semi-analytical solutions behave over time and converge to the exact solution is shown in detail with 2D figures. Also, it is shown comparison of semi-analytical solutions with exact solutions and error analysis with the help of tables. It has been discussed the methods are compared with each other and whether they are suitable for the K-S dynamical equation.
Ternate Sultanate Palace: A Multifaceted Hub at the Crossroads of Culture and Politics
Authors:   Fakultas Keguruan dan Ilmu Pendidikan Universitas Khairun, Indonesia, Hasim Rustam , Hasim Daud ,   Fakultas Ekonomi Universitas Khairun, Indonesia, Amelia Rasti ,   Fakultas Hukum Universitas Khairun, Indonesia
Published: December 2023

Historically, sultans have always had living space (lebenschraum habitus). In the Sultanate of Ternate, the living space of the sultans was the kadaton (palace) which since its birth was organized according to the philosophical cosmology constructed in a person’s customs. The palace (kadaton) as the basis of political legitimacy means that the palace is not merely the residence of the king and his relatives, but it is also seen as the state itself (exemplary state), so that in the history of its development, the palace has become an institution of power that politically has the same weight as the institution nobility itself. This research aims to 1) to reveal the Myth of the Seven Princesses: Source of Legitimacy, and 2) to reveal how the Sultan’s palace strengthened the Cultural and Political Center. This research used descriptive qualitative method. The result of this research revealed that the Sultanate of Ternate attempted to build and maintain its power base based on three factors. First, geopolitics, which causes the palace to have a traditional identity position that is closely related to the source of magical beliefs. Second, the doctrine of power, the palace has a central doctrine which makes the king the representative of God’s power (micro cosmos). Third, the basis of aristocratic power centered on cultural hegemony.
Framing Analysis of the Suspected Corruption Case of Agriculture Minister Syahrul Yasin Limpo
Authors:   Faculty of Communication and Creative Design, Universitas Budi luhur Jl. Ciledug Raya, Petukangan Utara, Jakarta Selatan, Daerah Khusus Ibukota Jakarta 12260, Indonesia., Maharani, Tasya Lee , Vera Nawiroh ,   Faculty of Communication and Creative Design, Universitas Budi luhur Jl. Ciledug Raya, Petukangan Utara, Jakarta Selatan, Daerah Khusus Ibukota Jakarta 12260, Indonesia.
Published: December 2023

Corruption is one of the deep-rooted problems in this country. One of the corruption cases that caught the public's attention and also received media attention was the corruption case of Minister of Agriculture Syahrul Yasin Limpo or commonly known as SYL. SYL's corruption case was widely reported in various mass media, one of which was Detik.com. News is the result of media construction. The content of each news is determined by several factors such as media ideology, ownership factors, and individual factors from the news journalist. One method of analysis to see how the media constructs a news narrative can use news framing analysis. This research is descriptive qualitative research with a constructivist paradigm perspective. This study aims to analyze how Detik.com framed the news of SYL's suspected corruption case. The news used are 3 news articles that were posted at the time of SYL's alleged arrest (October 12-13, 2023). The framing analysis used is Robert N. Entman's framing model which has 4 main elements: 1. Problem identification, what the problem is framed as; 2. Diagnoses causes, causal logic related to the problem; 3. Make moral judgment, what moral values are highlighted by the media; and 4. Solution, what solutions are highlighted in the news frame. The results showed that Detik.com reported on SYL's corruption case which showed the firm action taken by the KPK for corruption cases in the Ministry of Agriculture. The total amount of corruption money of SYL and 2 other perpetrators KS and MH was reported 1 day after the day of being arrested and questioned. With this news, hopefully there will be no more corruption cases in the Ministry, or in other institutions.
Analysis of Regional Government Financial Performance on the Human Development Index in West Nusa Tenggara Province
Authors:   Faculty of Economics and Business, University of Mataram & Lombok, Indonesia, Rizkika Dwi Herni , Firmansyah M. ,   Faculty of Economics and Business, University of Mataram & Lombok, Indonesia
Published: December 2023

Regional Financial Performance is a parameter used to determine the success or failure of regional governments in implementing their policies to achieve financial management strategies. According to Minister of Home Affairs Regulation Number 13 of 2006, performance is the output or result of a project or program that will be completed in connection with the use of the budget, both quantity and mixed quality. This research aims to determine and analyze the Financial Performance of Regional Governments, especially the Financial Independence Ratio, the Degree of Fiscal Decentralization Ratio, the PAD Effectiveness Ratio, the PAD Efficiency Ratio, Regional Financial Dependence, and the Human Development Index. The population used in this research were ten regencies/cities in NTB Province such as West Lombok, Central Lombok, East Lombok, North Lombok, Mataram City, Bima City, Bima, Sumbawa, West Sumbawa, Dompu, for the period 2018 - 2022. This research uses quantitative methods with multiple linear regression analysis techniques for panel data.
Stimulation of motor skills through game models in early childhood and elementary school students: systematic review in Indonesia
Authors: Suryadi Didi , Nasrulloh Ahmad , Yanti Novi , Ramli Ramli , Fauzan Lazuardy Akbar , Kushartanti BM. Wara , Sumaryanti Sumaryanti , Suhartini Bernadeta , Budayati Eka Swasta , Arovah Novita Intan , Mashud Mashud , Suganda Mikkey Anggara , Sumaryanto Sumaryanto , Sutapa Panggung , Abdullah Nagoor Meera bin , Fauziah Ella
Published: December 2023

Background and purpose of the study. The relevance of motor skills for every student since they have benefits and affect the overall development of kids. Several studies have offered data on learning and developing motor abilities in youngsters. The game model's information is extensively created and utilized as a reference to enhance gross motor abilities. As a result, the purpose of this study is to conduct a review of the scientific literature in Indonesia on the stimulation of motor skills in early childhood and primary school students through learning using game models. The Harzing Publish or Perish tool was utilized for the search in this study. A database (Scopus) was utilized to find publications on motor skill development through play-based learning. The search was carried out in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) recommendations. Only five items remained after the exclusion criteria were applied. The findings indicate that the research methods employed in cooperative learning research in Indonesia are various, including quantitative, mixed research (quantitative and qualitative), and development. On average, measuring equipment was utilized to collect data for the study. According to the findings of this review, in the first group, traditional play-based children's learning is capable of optimizing kindergarten children's basic motor development, with a track record of implementing the concept/theoretical basis, activity stages, social systems, reaction principles, support systems, and impact models, and increasing students' basic skills for high motor skills. In the second category, learning structured in the form of games may stimulate children's fine motor and cognitive abilities, as well as strengthen fundamental motor skills and build gross motor skills for use in the learning process. Some shortcomings in the review have been identified, and it is important to continue this study internationally with a literature review or mapping study (bibliometric and scientometric), as well as to conduct research on the use of the game model and its impact.
Keywords: Motor skills, play model, early childhood, elementary school
The quantitative genetics of human disease: 1. Foundations
Authors: Cutler David J. , Jodiery Kiana , Bass Andrew J. , Epstein Michael P.
Published: December 2023

In this the first of an anticipated four paper series, fundamental results of
quantitative genetics are presented from a first principles approach. While
none of these results are in any sense new, they are presented in extended
detail to precisely distinguish between definition and assumption, with a
further emphasis on distinguishing quantities from their usual
approximations. Terminology frequently encountered in the field of human
genetic disease studies will be defined in terms of their quantitive genetics
form. Methods for estimation of both quantitative genetics and the related
human genetics quantities will be demonstrated. The principal target
audience for this work is trainees reasonably familiar with population
genetics theory, but with less experience in its application to human disease
studies. We introduce much of this formalism because in later papers in this
series, we demonstrate that common areas of confusion in human disease
studies can be resolved be appealing directly to these formal definitions. The
second paper in this series will discuss polygenic risk scores. The third paper
will concern the question of “missing” heritability and the role interactions
may play. The fourth paper will discuss sexually dimorphic disease and the
potential role of the X chromosome.
Background: With over a hundred years of history, most fundamental
results in quantitative genetics are well known to most population genetics
students, yet there is often considerable confusion concerning precise
definitions and assumptions, particularly when interactions may exist. The
connections between quantitative genetics and human disease genetics can
be obscure to many.
Methods: Fundamental quantitative genetics quantities are derived as
conditional expectations of phenotype. Genetic, environmental, additive,
dominance and interaction effects and their associated variances are defined,
with key results explicitly derived. The effects of linkage disequilibrium and
methods to account for it are examined. Methods to estimate and interpret
heritability are discussed.
Results: Application of quantitative genetics quantities are extended to
binary traits with special emphasis on translation between commonly
estimated human disease genetics quantities and their corresponding
quantitative genetics representations.
Conclusions: The distinction between modeling definitions and assumptions
is made clear. Methods to unite human disease genetics and quantitative
genetics are elucidated. Methods to account for linkage disequilibrium and
other forms of interaction are described.
Avaliação in silico da interação do derivado de heparina não anticoagulante Dociparstat Sodium (DSTAT) com LPG3 e de seu efeito in vitro na infecção de macrófagos por Leishmania chagasi
Authors:   , Garcia Ingrid Rabite
Published: December 2023

Contextualização: Há uma necessidade urgente de novos tratamentos para combater a Leishmaniose Visceral (LV). A proteína LPG3 de Leishmania chagasi foi considerada por nosso grupo de pesquisa como potencial alvo para novos fármacos contra LV.O bloqueio dessa proteína pela heparina sódica reduziu a internalização de formas promastigotas do parasita em macrófagos. No entanto, o uso da heparina sódica na LV é limitado devido a sua potente atividade anticoagulante. Objetivo: Investigar in silico e in vitro a hipótese de que o bloqueio da proteína LPG3 pela heparina não-anticoagulante (DSTAT) interfere no processo de infecção parasitária. Métodos: Primeiramente, previmos in silico a interação de DSTAT com a proteína LPG3, bem como sua afinidade de ligação, utilizando docking molecular do tipo receptor-ligante. Em seguida, DSTAT foi utilizada em ensaios in vitro para testar a toxicidade em macrófagos RAW 264.7, sua atividade leishmanicida contra formas promastigotas de L. chagasi e sua atividade antileishmania em processos de adesão e internalização de formas promastigotas de L. chagasi em macrófagos. Resultados: O docking molecular revelou a ligação de DSTAT no sítio previsto para heparina na proteína LPG3 com uma afinidade de ligação ligeiramente maior que a heparina sódica. Nos ensaios in vitro, as concentrações testadas de DSTAT não foram tóxicas para os macrófagos e a maior concentração selecionada (300 µg/mL de DSTAT) não apresentou efeito leishmanicida contra formas promastigotas de L. chagasi. Por outro lado, DSTAT (100 µg/mL) levou à redução na internalização de L. chagasi em macrófagos, sem interferir na adesão parasitária. Conclusão: Tratamento com heparina não-anticoagulante DSTAT interfere na infecção de macrófagos por formas promastigotas de L. chagasi, provavelmente pelo bloqueio da proteína LPG3 do parasito, sem causar toxicidade para ambas células. Palavras-chave: LPG3. Leishmaniose Glicosaminoglicanos. Heparina. Visceral. Leishmania chagasi.
Avaliação da atividade biológica de produtos naturais e sintéticos visando o tratamento de feridas ocasionadas por leishmaniose tegumentar: estudo in vitro e in silico
Authors:   , Barbosa Pedro Henrique de Jesus
Published: December 2023

A Leishmania. V. braziliensis é o agente etiológico da Leishmaniose Tegumentar (LT) doença que afeta milhares de pessoas, principalmente aquelas em estado de vulnerabilidade social. O tratamento normalmente que é utilizado para tratar essa doença é baseado em fármacos que possuem toxicidade e custos elevados. Sendo assim, a busca de compostos químicos é essencial para o seu controle e tratamento. A busca de compostos oriundos de produtos naturais, advindos da flora ou fauna ou sintéticos através da química medicinal é de grande importância. Neste contexto, o presente trabalho tem como objetivo avaliar o potencial de alcaloides indólicos e derivados de dibenzoilmetanos como cicatrizante e leishmanicida.tal, foram feitos testes in vitro para avaliar a citotoxicidade em células de macrófagos RAW264. Os compostos que obtiveram uma taxa de viabilidade maior que 80% foram selecionados para os demais testes como atividade anti-inflamatória, atividade antioxidante para avaliar a capacidade de proteção contra danos oxidativos e pela técnica inibição do radical livre DPPH, e posteriormente atividade leishmanicida por infecção em macrófagos. Em seguida os compostos que tiveram como destaques para serem utilizados como tratamento de leishmaniose tegumentar foram levados para análise in silico para avaliar o potencial dos compostos dentro das regras de lipinski e ADMET. Os resultados obtidos apontaram três alcalóides e dois derivados de dibenzoilmetanos como potenciais agentes leishmanicida, cicatrizantes e anti- inflamatório. Palavras-chave: Cicatrização. Leishmaniose tegumentar. Produtos naturais.
Percutaneous Deep Venous Arterialization for the Treatment of Buerger’s Disease
Authors:   University of New England College of Osteopathic Medicine, Biddeford, Maine, T Moriarty Kevin , H Rundback John ,   Advanced Interventional and Vascular Services, Teaneck, New Jersey, Shackles Christopher ,   Advanced Interventional and Vascular Services, Teaneck, New Jersey
Published: December 2023

Purpose: Percutaneous deep venous arterialization (DVA) using a stent-graft system is a novel endovascular approach in the treatment of patients with Buerger’s Disease.
Sources of valuable traits for the selection of varieties and hybrids of agricultural crops on the Yaltushkiv EBS
Authors: Orlov S. D. , Kornieieva M. O. , Hrytsyshyna L. H.
Published: December 2023

Purpose. To identify sources of economic and valuable traits for the breeding process of industrial, grain and bioenergy crops at the Yaltushkivska Experimental Breeding Station of the Institute of Bioenergy Crops and Sugar Beet of the National Academy of Agrarian Sciences.
Methods. Hybridization, selection, field tests, analytical, mathematical and statistical.
Results. The best breeding genotypes of beets of foreign and domestic selection that are the donors of valuable traits, are concentrated at the Yaltushkivska EBS. The best hybrid combinations created on the basis of the Yaltushkivska EBS materials and evaluated in the variety test under the Beta cross program significantly exceeded the group standard: in yield (103.6–114.9%), sugar content (96.4–105.7%), sugar yield (110.1–110.8%). A highly productive buckwheat variety ‘Yuliana’ with a yield of 2.2 t/ha and a protein content of 15.0% was created and submitted for state variety testing. The best highly productive and energy valuable varieties of switchgrass were selected for cultivation in areas of insufficient and unstable soil moisture, which ensure the yield of dry biomass at the level of 7.5–16.2 t/ha, the yield of solid biofuel of 8.2–17.2 t/ha, and energy of 112.5–243 GJ/ha. Genotypes from the Miscanthus genus have been identified, which combine signs of tolerance to osmotic and salt stress and high energy yield.
Conclusions. Selected sources of breeding-valuable traits became the basis for creating varieties and hybrids of agricultural crops (sugar beet ‘Barskyi’, ‘Chereshnevyi’, ‘Ruthenia 11’, ‘Ruthenia 12’, ‘Ruthenia 13’, etc., buckwheat ‘Yuliana’, switchgrass ‘Morozko’ and ‘Liadovske’ and varieties of miscanthus resistant to abiotic factors of the environment). Breeding genotypes and original lines of these crops were transferred to the National Center of Plant Genetic Resources of Ukraine.
Effect of Cash Storage on the Financial Performance of Commercial Banks in Kenya
Authors: Onwonga Mactosh
Published: December 2023

Purpose: The study sought to establish the effect of cash storage and on financial performance of commercial banks of Kenya.

Methodology: The research was carried out through a descriptive survey research design. Descriptive design was used because it focused on complex analysis to bring out the correlation of variables. The study population was all the 43 commercial banks registered and licensed to operate in Kenya. These commercial banks formed the unit of analysis. A census was conducted on all the banks. The sampling frame of the survey of the banks was one head of operations and head of finance from each of the 43 commercial banks located in Nairobi County. The target respondents was hence 86. The study used both primary and secondary data for analysis. Inferential analysis techniques including correlation, regression and t-tests were used to achieve the study objectives. SPSS version 21 was used for analysis.

Findings: The study findings indicated that the correlation between, cash storage and financial performance is positive. Further results indicated cash storage had a positive significant effect on cash storage and ROA is positive and significant.

Unique Contribution to Theory, Practice and Policy: The study was anchored on cash management theory to evaluate the effect of cash storage on the financial performance of Commercial Banks in Kenya. The study recommends that commercial banks and other financial institutions involved in handling of cash should put in place proper reconciliation practices for instance increasing the frequency of reconciling books. The study also recommends that advanced practices of cash storage for instance investing in fire proof safes for storing cash and also in closed circuit television security cameras for surveillance of cash storage areas and also invest in alarm system in cash storage areas and also restricted access to cash storage areas by lock, key, passwords and other security measures so as to reduce fraud arising as a result of poor cash storage practices.
ҰЖЫМДАСТЫРУ ҚАРСАҢЫНДАҒЫ (1925-1929 ЖЖ.) ГУРЬЕВ УЕЗІНІҢ ӘКІМШІЛІК-ТЕРРИТОРИЯЛЫҚ ҚҰРЫЛЫМЫ, ХАЛҚЫНЫҢ ҚҰРАМЫ ЖӘНЕ ҚОЖАЛЫҚТАРЫ: СТАТИСТИКАЛЫҚ МӘЛІМЕТТЕР ТАЛДАУ
Authors: Zhumabayeva Zhumaziya , Sakpalieva Aida
Published: December 2023

Мақала Кеңес өкіметінің ХХ ғасырдың 30-жылына дейін көшпелілік ғұрпын сақтаған қазақ қожалықтарын социалистік негізге көшіру барысында жүргізген реформаларының заңсыздығын Гурьев өңірі мысалында ашуға ықпал ететін мәселелерге арналған. Мақалада байларды тәркілеу мен ұжымдастыру қарсаңындағы Гурьев уезі құрамындағы көшпелі қазақтар тұратын болыстықтар мен ауылдардың әкімшілік-территориялық құрылымын, өңірді мекендеген халықтың ұлттық, әлеуметтік құрамын, мал шаруашылығымен айналысатын жеке меншіктегі қожалықтардың санын және мал саны көрсеткіштерін салыстырмалы талдау, саралау арқылы зерттеу қорытындылары шығарылды. Атап айтқанда, Гурьев уезінің жайсыз климаттық ерекшеліктеріне орай, бұл өңірдегі жеке қожалықтардың Қазақстанның өзге аймақтарына қарағанда шаруашылықтық әлсіздігі мал санының аздығымен тұжырымдалады. Сонымен қатар, өңірдегі қазақ қожалықтарының экономикалық әлсіздігі 1918-1920 жылдардағы уезд аумағындағы Азамат соғысы зардаптарымен және 1921-1923 жылдардағы бірнеше дүркін болған қуаңшылық пен жұтпен байланыстырылады.
Гурьев уезіндегі кеңестендіру шаралары барысында жүргізілген әкімшілік-территориялық өзгерістердің көптігі халықтың әлеуметтік-экономикалық құрылымына ықпал еткені 1926-1929 жылдар аралығында салыстырылып талданады. Өңір халқының ұлттық жағынан салыстырмалы түрде біркелкілігін көшпелі мал шаруашылығының басымдығымен негіздейді. Бұл талдаулар Гурьев өңіріндегі 1928 жылғы ірі байларды кәмпескелеу, 1929-1933 жылдардағы мал және ет дайындату және ұжымдастыру сияқты саяси науқандарды әділетсіз өткенін ашуға ықпал етеді, Уезд аумағында кәмпескелеу шарттарына сәйкес келетін қожалықтардың болмағанын дәлелдейді.
CЫБAЙЛAC ЖEМҚOPЛЫҚ ҚЫЛМЫCТAPЫНЫҢ КPИМИНOЛOГИЯЛЫҚ ACПEКТІЛEPІ
Authors: Shayakhmetova Zhanna
Published: December 2023

Мaқaлaдa cыбaйлac жeмқopлықтың кpиминoлoгиялық acпeктілepін eгжeй-тeгжeйлі жәнe кeзeң-кeзeңімeн aшyғa әpeкeт жacaлды. Cыбaйлac жeмқopлық әpeкeттepі eлдің экoнoмикaлық жәнe әлeyмeттік дaмyынa тepіc әcep eтeді. Қaзaқcтaн үшін cыбaйлac жeмқopлық пpoблeмacы eліміздің құқық қopғay opгaндapы мeн coт жүйecінің бeдeлінe нұқcaн кeлтіpeтін aca мaңызды құқықтық, экoнoмикaлық, caяcи міндeттepді шeшyгe кeдepгі кeлтіpeтін мaңызды мәceлeлepдің біpі бoлып тaбылaды.
Қaзaқcтaн Pecпyбликacы Пpeзидeнтінің Жoлдayындa cыбaйлac жeмқopлық жaй ғaнa құқық бұзyшылық eмec eкeндігі көpceтілгeн. Бұл мeмлeкeттің тиімділігінe дeгeн ceнімгe нұқcaн кeлтіpeді жәнe ұлттық қayіпcіздіккe тікeлeй қayіп төндіpeді. Eлдeгі cыбaйлac жeмқopлықтың бacты ceбeптepінің біpі мeмлeкeттік құpылымдapдың қызмeтін, бacқapy жүйecін күpдeлі ұйымдacтыpyды тиіcіншe бaқылaмay бoлып caнaлaды.
Зерттеу барысында Еуропалық зерттеушілер білім беру саласындағы сыбайлас жемқорлыққа қарсы күрестің пайдасына дәлелдер келтірді. Мақалада сыбaйлac жeмқopлыққa қapcы caяcaт өміpдің әpтүpлі caлaлapындa cыбaйлac жeмқopлықты тyдыpaтын жәнe aдaмдapды cыбaйлac жeмқopлық әpeкeттepін жacayғa итepмeлeйтін ceбeптep мeн жaғдaйлapды aзaйтy бoйыншa мeмлeкeттің жaн-жaқты жәнe дәйeкті шapaлapын әзіpлey жәнe жүзeгe acыpy қарастырылған.
Автормен қылмыcтық-құқықтық жәнe кpиминoлoгиялық шapaлapдың нeгізгі бaғыттapы жeкeлeгeн іc-шapaлapды жүзeгe acыpy шaмacынa қapaй ғaнa eмec, coндaй-aқ cыбaйлac жeмқopлық құбылыcын, oның ceбeптepін, cыбaйлac жeмқopлық мінeз-құлқының yәждeмecін тepeң тaлдay нәтижeлepін, тікeлeй жәнe жaнaмa шығындapды нeғұpлым бaйcaлды жәнe oбъeктивті бaғaлayды ecкepe oтыpып түзeтілy ұсынылаған.
The Effect Of Net Circumference Speed On Purse Seine Catches (Case Study: KM. Mekar Baru Putra 3)
Authors: Wulandari Ully , Suharyanto Suharyanto , Sutono Dian , Maryanto Yanto
Published: December 2023

In March-July 2022, the research was conducted using the case study method on board the Mekar Baru Putra 3 Motor Ship based at the Nusantara Fishing Port in Pekalongan, Central Java. The aim is to determine the effect of the speed of purse seine net circumference on fish catches at KM Mekar Baru Putra 3 which is based on Pekalongan VAT. Data collection was carried out by survey method following fishing activities conducted by KM Mekar Baru Putra 3. The data collected are primary data in the form of: a) net circumference time, b) number of catches. Data was collected using stopwatches and stationery, then analyzed by regression analysis. In this study, the normality test results showed a significant value of 0.200. The value is greater than 0.05 which means the data is normally distributed. The results of the analysis were then carried out to see the linearity of pulling the wrinkle rope against the catch. From the test results, it is known that the value of Sig. deviation from linearity is 0.022 < 0.05, it is said that there is no linear relationship between the circular time speed and the catch.
Use of Anthropology in Developing Sustainable Projects
Authors: Arafin Murshedul , Ahmed Jubayer
Published: December 2023

A multitude of divergent interpretations exist about sustainability, the most of which originate from enduring European customs surrounding the use of natural resource management. Anthropology is based on the same ontology that caused the global ecological crisis, which marked the beginning of the new era in which we live. We can offer a different perspective on the concept of sustainability by recognizing that anthropologists have a responsibility to demonstrate the importance of social, cultural, and ontological diversity for resilience, adaptation and sustainable innovation.
Diachronic Aspects of the Bulgarian Anthroponymic System in the 19th Century. Linguistic Features. Trends
Authors:   INSTITUTE FOR BULGARIAN LANGUAGE, BULGARIAN ACADEMY OF SCIENCES, Braga Tatyana B
Published: December 2023

The article presents results of a study of the historical aspects of Bulgarian anthroponymy obtained as part of a postdoctoral project. The study is based on 19th-century archival materials that have been introduced into scientific circulation only recently. It reveals the unique features of the formation of the anthroponymy characteristic of a Bulgarian community outside Bulgaria’s ethnic territory. The study presents linguistic and statistical data on 19th-century Bulgarian personal names, highlighting the changes in the personal name system of the settlers in Tabak (South Bessarabia) that took place under polylinguistic influence.
FORMULAÇÃO DE UM CÓDIGO DE ÉTICA PARA UMA EMPRESA DO SETOR DA CONSTRUÇÃO CIVIL NO MUNICÍPIO DE FAINA-GO
Authors: Guerra de Morais Beatriz , Da Silva Santos Giovanna , Camilo da Silva Nogueira Ítalo , De Araújo Nóbrega Natália , Ramos Tavares Renato , Siqueira Alves Vitória
Published: December 2023

O Código de Ética Empresarial sumariza, por intermédio de um conglomerado de regras de conduta profissional, a visão, a missão e os valores da empresa, direcionando, assim, o comportamento e atitude que deve ser seguido por todos os níveis hierárquicos da organização. Nesse panorama, o objetivo do presente artigo visa elaborar um código de ética para a empresa Construfaina Materiais de Construção (nome fictício). Para alcançar este objetivo, metodologicamente, desenvolveu-se uma pesquisa qualitativa conjuntamente a um estudo descritivo, exploratório e bibliográfico. Os resultados refletem que o processo de elaboração de um código de ética empresarial envolve princípios, vedação, direitos e deveres profissionais, que originam um manual que determina os preceitos morais admissíveis na organização.
Enhancing Phishing Awareness Strategy Through Embedded Learning Tools: A Simulation Approach
Authors:   Federal University of Lafia, Nigeria, Ahmad Bamanga Mahmud , Ahmed Shehu Mohammed ,   Federal University of Lafia, Nigeria, Sylvanus Dikko Elisha ,   Federal University of Lafia, Nigeria
Published: December 2023

Phishing attacks pose a persistent threat to individuals and organizations, demanding effective strategies for enhancing awareness and response. This research investigates the use of a web-based application employing simulation-based training and embedded learning tools to bolster phishing awareness. The study creates a comprehensive system that includes user roles, training modules, simulated phishing scenarios, and a robust database structure. Through rigorous testing, bug fixing, and user training, the application is deployed for real-world use. Results show that the web-based application significantly improves users' ability to detect and respond to phishing attempts. Notably, the integration of embedded learning tools enhances engagement and knowledge retention. The research contributes to proactive cybersecurity practices by offering a practical solution for countering phishing attacks. While addressing limitations of prior studies, this work opens avenues for further research in real-world applicability, long-term effectiveness, scalability, and user motivation. Ultimately, the web-based application serves as a valuable tool in building robust phishing awareness and mitigating cybersecurity risks.
Post-Study Phase
Authors: van Loen Harry , Landuyt Hanne
Published: December 2023

Archiving, data management reports and data sharing procedures.
A Short Review on Charge Packets and Space Charge Properties Inside Dielectrics
Authors: Vardakis George , Danikas Michael G. , Achillides Zenon
Published: December 2023

An effort to highlight the role of space charges inside dielectrics and their propagation is made in the present paper. Solid insulating materials in various parts of high voltage devices and machines are crucial for the insulating performance and their reliable functioning duration. Space charge distributions and space charge propagation in the form of pulses, called charge packets, are studied in this paper pointing out on one hand the initiating mechanisms and on the other hand the propagation mechanisms of charges inside dielectrics, as they are introduced in the scientific literature. Experimental data are used from other papers, mainly those referring to space charge distributions versus space and simultaneously versus time in a classification attempt of the aforementioned parameters.