bluuebunny/crossref_metadata_2025 huggingface dataset:
КОНЦЕПТУАЛЬНАЯ СИТУАЦИЯ ЖЕЛАНИЯ В ЛОГИЧЕСКОМ АСПЕКТЕ
Authors: Алтабаева Е.В.
Published: October 2024

В работе представлен анализ логической природы ситуации желания для выявления форм мысли, соотносимых с этой ситуацией, и ее концептуальной специфики. Соответствующий концепт с позиций логики рассматривается как концептуальнологическая основа категории оптативности. Выявлена специфика мира желаний как одного из иных миров, в основе которого лежит виртуальный нерасчлененный концепт, не имеющий реального референта во внешнем мире, но обладающий двойной обращенностью. Установлено, что оценочный компонент входит в структуру оптативной ситуации, ирреальной по своей природе

The main objective of this paper is to analyze logical nature of desire situation to reveal the forms of thought, related to this situation, and its conceptual speci c character. The appropriate concept from a logical standpoint is considered as conceptual and logical base of the category of optation. In the course of the research, we discovered that sentences with semantics of desire cannot be solely quali ed by modal logic according to the type of assessment due to the originality of the concept, which we are researching, and the modal semantics of the same name. Epistemic modality is most close to optation when determined by the following factors of nonlogical order, which are not always acknowledged or controlled by the subject: habits, inclinations, and preferences. We cannot deny a certain connection between desire and ability, necessity and, especially, incentive. The commonality of logical (notional) part of the appropriate concept and content of assessments, di erent in ontological sense, may be explained from positions of semantics of the possible worlds and can be determined by the relationships between the sphere of the speakers desire and objective reality, between the Me world and the non Me world (we imply the individuals reaction to di erent things, phenomena or events (both real and virtual) in the form of their comparison, their positive evaluation and applying them to ourselves). We revealed the speci cs of the world of desires as one of the other worlds, which is based on the virtual indiscrete concept, which has no real reference in the outside world, but has two addressees: the outside world, on the one hand, and some possible world, on the other hand. Moreover, desires are one of the types of assessments and this way they are found outside of category of truth, but correlate with value assessments as special assessments about fragments of a possible, another world, positively valued and desired by the subject. The evaluation component is part of the structure of optative situation. We conclude that the object of desire can be only an unreal situation: the desire of the subject for something that he doesnt have at the present moment, even if this is about preserving and maintaining the desired situation in the future. The question of the degree of controllability/uncontrollability of desire should not be considered resolved
Investigation of Tandem Queuing Systems Using Machine Learning Methods
Authors: V.M. Vishnevsky , A.A. Larionov , A.A. Mukhtarov , A.M. Sokolov
Published: October 2024

This paper considers tandem queuing systems with limited buffer sizes in each phase. The system handles an incoming correlated MAP flow and the service time obeys a PH-distribution. Models of such systems and methods for their investigation are briefly reviewed from the historical perspective. According to the review, the problem statement presented below, the methods proposed for solving this problem, and the corresponding results are novel. An accurate algorithm for calculating the performance characteristics of low-dimensional tandem queuing systems is described, including an estimate of the algorithm’s complexity. An approach using both machine learning and simulation modeling is suggested for the investigation of high-dimensional tandem queuing systems. Numerical analysis results are provided to show the effectiveness of machine learning methods for estimating the performance of tandem queuing systems.
An Identification-Based Control Method for an Overhead Crane with a New Combined Sensor Placement
Authors: S.P. Kruglov , S.V. Kovyrshin , D.V. Butorin
Published: October 2024

This paper is devoted to an automatic control method for an overhead crane under the current parametric uncertainty of the crane, transported cargo, and exogenous disturbances. The control objective is to move the cargo in the horizontal plane to a point ensuring the final delivery of the cargo to the designated place while parrying the angular oscillations of the suspension and reaching given dynamic characteristics. The approach is based on a control scheme with a current parametric identification algorithm, an implicit reference model, and “simplified” adaptability conditions to track cargo movements directly. The control law generates a given trolley speed for the servo drive. The passport data of the crane installation are used to select the control law parameters. Unlike previous publications on the topic, the solution proposed below is simpler, more reliable in terms of operation, and less expensive. This is achieved by placing a combined sensor (an accelerometer with an angular rate sensor (ARS)) on a suspension cable near the crane trolley and applying, first, an algorithmic solution without the preliminary calculation of the ARS drift and, second, a current parametric identification procedure of higher efficiency. Computer simulation results are provided to confirm these advantages of the new solution. A similar example is implemented on an experimental installation.
Anwendung von Machine Learning und Deep Learning im automatisierten Finanzhandel
Authors: Tansel Dogus , Ritz Harald , Hein Oliver
Published: October 2024

Zunehmend kristallisieren sich zukunftsorientierte KI-Ansätze als Trend zur Automatisierung des finanziellen Handels mit Blick auf Machine Learning und Deep Learning-Methoden heraus. Insbesondere DL-Modelle haben in den letzten Jahren im Finanzsektor an Bedeutung gewonnen, da sie in der Lage sind, komplexe Zusammenhänge und Muster innerhalb der Datenmengen zu erkennen, die für menschliche Händler schwer zugänglich sind.
Der Artikel stellt ganzheitliche Ansätze zur Entwicklung intelligenter Handelssysteme und die damit einhergehende Nutzbarkeit vor. Hierbei ist das Ziel,  zu untersuchen, wie der Einsatz von DL-Modellen innerhalb eines Handelssystems realisiert werden kann. Im Rahmen dieser Realisierung steht dabei die Entwicklung und Anwendung eines algorithmischen Handelssystems für das Treffen automatisierter Handelsentscheidungen im Fokus. Teilnehmer auf den Finanzmärkten stehen vor der spannenden Aufgabe, verschiedene Ansätze zu berücksichtigen. Ob sie sich für den Einsatz von klassischen ML- oder erweiterten DL-Modellen entscheiden oder ob Techniken zur Preis- und Trendvorhersage eingesetzt werden, hängt von den individuellen Zielen und Präferenzen ab.
Designing a Use Case for Supply Chain Resilience Based on Process Mining
Authors: Sekulovska Angela , Morelli Frank , Siurdyban Artur , Manfreda Anton , Schätter Frank
Published: October 2024

Amidst global disruptions, the significance of Supply Chain Resilience (SCR) has surged in scholarly and practical discourse. This paper endeavors to craft an industry-neutral conceptual dashboard, tailored for in-house consultants, to measure and oversee SCR. Drawing from the SCOR model's resilience metrics, Key Resilience Areas (KRAs), and Accenture’s SCR application, this study presents a practical use case for deploying such a dashboard. Expert evaluation by process mining and supply chain specialists highlighted potential enhancements for the dashboard.
Experimente zur GPT-3.5-unterst¨utzten Entwicklung von Prozessmodellen
Authors: Simon Carlo , Haag Stefan , Zakfeld Lara
Published: October 2024

Noch können Prozessmodelle nicht automatisch aus textuellen Beschreibungen generiert werden. Die Vorteile einer solchen Technologie lägen in kürzeren Entwicklungszeiten und einer kohärenteren, weil algorithmischen Interpretation des Inputs. Dazu müssten Methoden der formalen Modellierung und der Linguistik kombiniert werden. Die aktuellen GPT-Modelle eröffnen gerade hinsichtlich der linguistischen Analyseneue Möglichkeiten. Dieser Beitrag untersucht, ob die Fähigkeiten von GPT-3.5, Texte zusammenzufassen, kausale Zusammenhänge zu erkennen oder Begriffe zu klassifizieren, auch ausreichen, um formale Prozessmodelle zu erstellen. Hierzu wurden systematisch Experimente zur Nutzung von GPT-3.5 durchgeführt. Dabei konnte beobachtet werden, dass die Resultate abh¨angig von den gewählten Transformer-Optionen erheblich variieren. Die Protokolle der Experimente werden in diesem Beitrag zusammengefasst und aus den Ergebnissen dann mögliche, künftige Forschungsaktivitäten abgeleitet.
Development of the First-in-Class FEM1B-Recruiting Histone Deacetylase Degraders
Authors: Feller Felix , Honin Irina , Miranda Martina , Weber Heiko , Henze Svenja , Hanl Maria , Hansen Finn Kristian
Published: October 2024

Targeted protein degradation (TPD) represents a promising alternative to conventional occupancy-driven protein inhibition. Despite the existence of more than 600 E3 ligases in the human proteome, so far only a few have been utilized for TPD of histone deacetylases (HDACs), which represent important epigenetic anticancer drug targets. In this study, we disclose the first-in-class Fem-1 homolog B (FEM1B)-recruiting HDAC degraders. A set of twelve proteolysis targeting chimeras (PROTACs) was synthesized using a solid-phase supported parallel synthesis approach utilizing a covalent FEM1B ligand as E3 ligase warhead. The evaluation of the HDAC degradation efficiency revealed substantial HDAC1 degradation by the top performing degrader FF2049 (1g: Dmax = 85%; DC50 = 257 nM). Unlike our previously published cereblon-recruiting selective HDAC6 degrader, A6, which uses the same HDAC ligand, the FEM1B-based PROTACs achieved selective HDAC1-3 degradation. This unexpected change in HDAC isoform degradation profile was accompanied by significant enhancement of the anticancer properties.
A Glycosylation Mechanism Case Study: Unraveling the Mechanism of Stereospecific Self-promoted N -Glycosylations
Authors: Faurschou Natasha Videcrantz , Sauer Stephan P. A. , Pedersen Christian Marcus
Published: October 2024

In this study, the mechanism of self-promoted N-glycosylations is extensively investigated through kinetic experiments, computational studies, and nucleophilic competition experiments. Based on the findings, the mechanism is proposed to be initiated by proton transfer from the acidic sulfonyl carbamate to the trichloroacetimidate, upon formation of an associated contact ion pair. This ion pair then collapses in an SN 1-like fashion, forming an oxocarbeniumion-like intermediate. According to the proposed mechanism, stereospecificity arises from the associated nature of all intermediates formed throughout the reaction. During the mechanistic study, it was also found that the sulfonyl carbamates have catalytic properties if a competing nucleophile is present.
SiCN Nanofibers Supported Gold Catalyst for the Selective Oxidation of Cyclic Alkenes
Authors: Pillai Saravana K T
Published: October 2024

A general synthetic procedure for mesostructured metal nanoparticles integrated SiCN supports with preferable morphology has been developed. The synthetic procedure consists of two steps including i) concerted block copolymerization, microphase separation, and cross-linking ii) pyrolysis at 1000°C under inert atmosphere. Hydroxyl terminated polyethylene and an inexpensive commercially available polymeric carbosilazane precursor were used as organic and inorganic ceramic precursor blocks, respectively. The linked hybrid block copolymer is structured using microphase separation in a non-polar solvent. The synthesis of metal nanoparticles supported SiCN catalysts with fibrous morphology was synthesized by the addition of aminopyridinato complexes during copolymerisation step. The synthesized Au@SiCN-Nanofibers catalysts were characterized by Thermo gravimetric analysis, transmission electron microscopy, and powder X-ray diffractometer techniques. The Au@SiCN is active in oxidation of higher alkenes in the presence of air/O2 as an oxidant. More interestingly, Au@SiCN is highly selective in the cyclicalkenes over linear alkenes. Models of cyclicalkenes oxidation are conducted and analysed by using 1H NMR and GC-MS measurements.
S273 phosphorylation restricts PPARy structural dynamics - a multiscale modeling view on the mechanisms of obesity metabolism
Authors: Mariano Gonçalves Dias Marieli , Gil Herrero Cristina , Migliorini Figueira Ana Carolina , Thallmair Sebastian
Published: October 2024

The nuclear receptor PPARγ is a promising target for treating type 2 diabetes mellitus. It regulates gene expression related to insulin and lipid metabolism. The obesity-linked phosphorylation of PPARγ S273 disrupts the expression of a specific subset of PPARγ-controlled genes linked to insulin metabolism, such as adiponectin. Previous research has demonstrated that this post-translational modification alters interactions with several coregulators, thereby influencing the expression of upstream genes. However, the effects of phosphorylation on the structural dynamics of PPARγ have not yet been fully understood. In this study, we applied atomistic and coarse-grained molecular dynamics simulations to examine the structural and dynamic changes induced by S273 phosphorylation. We observed that the phosphorylation impacts the dynamics of adjacent residues and influences more distantly located structural regions. Furthermore, S273 phosphorylation alters the flexibility of H12, the region responsible for canonical interaction with coregulators, potentially accounting for the previously observed differential interactions. These findings provide new insights into the mechanisms of gene expression regulation and may expand the avenues into diabetes therapy studies through PPARγ modulation. Moreover, they highlight the potential of combined atomistic and coarse-grained simulations to elucidate modifications of structural dynamics in proteins upon post-translational modification.
Efficient Electrochemical Conversion of Nitric Oxide to Ammonia Using a Porous Nickel Catalyst in a Membrane Electrode Assembly Electrolyzer
Authors: Singh-Morgan Amrita , Trösch Kim , Weinfurter Anna , Inniger Michael , Xu Yuan-Zi , Mougel Victor
Published: October 2024

The electrochemical synthesis of ammonia presents a promising pathway to decarbonize and electrify the production of the world’s second-largest commodity chemical. Among potential reactants, NOx gases stand out due to their favorable thermodynamics, advantageous kinetics, and availability from both combustion emissions and nitrogen-fixation processes, such as plasma-induced atmospheric nitrogen oxidation. However, the typically low concentrations of NOx in these sources poses significant challenges for electrochemical performance, particularly due to limitations in reactant mass transport. In this work, we report on the use of a porous nickel catalyst in a membrane electrode assembly (MEA) electrolyzer to enable the direct use of a dilute nitric oxide (NO) feed. The rational optimization of reactant mass transport enabled achieving a NO-to-NH3 single pass conversion of 93%, a faradaic efficiency for ammonia of 92% and an ammonium production rate of 557 μmol/h·cm2.
El modelo pedagógico como catalizador de la formación en programas de ingeniería: caso ingenierías de la UPTC
Authors: Fernández Samacá Liliana , Alvarado Fajardo Andrea Catalina , Díaz Márquez Sonia Esperanza , Mujica Roncery Lais
Published: October 2024

El presente trabajo contiene el diseño de un Modelo Pedagógico, como marco de trabajo para la construcción de proyectos curriculares en Ingeniería. El Modelo propuesto se describe desde tres dimensiones: i) una dimensión conceptual, en la que se exponen los principios e intencionalidades que orientan la interacción de los actores del proceso formativo; ii) una dimensión relacionada con la enseñanza que orienta el papel de profesor de ingeniería en el desarrollo del proyecto curricular; y finalmente, iii) una dimensión asociada al aprendizaje, en la que se establecen aquellos aspectos relacionados con el estudiante y sus roles en el proceso formativo. Igualmente, el modelo pretende motivar un diálogo permanente entre los programas de ingeniería para definir estrategias que faciliten la interacción entre programas y con otras facultades promoviendo la integración de la ingeniería con otras áreas de conocimiento, y así, fortalecer la formación integral de los estudiantes y la inter y transdisciplinariedad de los proyectos curriculares. De esta manera, el Modelo sirve como catalizador en el reto de ‘formar profesionales como ciudadanos globales que sean capaces de resolver problemas en su entorno’. El Modelo propuesto emerge de los diálogos que, en torno a la reforma académica, se desarrollan en la Universidad Pedagógica y Tecnológica de Colombia, y orienta la construcción de proyectos curriculares desde la autonomía e individualidad de los programas.
Diseño de núcleos comunes desde la autonomía: una estrategia para promover la articulación de los programas de ingeniería
Authors: Mujica Roncery Lais , Fernández Samacá Liliana , Díaz Márquez Sonia Esperanza
Published: October 2024

En el marco de los procesos de construcción y gestión curricular en Ingeniería, se ha reconocido que los programas de ingeniería comparten intencionalidades, así como un marco común de competencias que se exige a sus egresados. En esta construcción, entre otros, se tienen en cuenta orientaciones internacionales, iniciativas de diseño curricular y lineamientos dados por la Asociación Colombiana de Facultades de Ingeniería (ACOFI), en armonía con los procesos de acreditación nacional definidos por el Consejo Nacional de Acreditación en Colombia, y a nivel internacional, por referentes como EUR-ACE y ABET. Este trabajo propone la creación de núcleos comunes como estrategia que facilita la gestión curricular en programas de ingeniería, a la vez que promueve la flexibilidad, la transversalidad, la inter y transdisciplinariedad curricular, la movilidad estudiantil, y el aprovechamiento de las capacidades institucionales. Estos núcleos son concebidos como ejes curriculares, capaces de articular y abordar problemáticas, habilidades y conocimientos comunes a varias titulaciones, los cuales, teniendo en cuenta el principio de autonomía, se configuran como espacios de concertación más no de homogenización. Esto es, un núcleo se crea si las apuestas allí identificadas sirven al menos a dos programas de Ingeniería, sin convertirse en camisa de fuerza para los demás. Así, los núcleos pueden tener un grupo considerable de cursos, sin implicar que todos sean obligatorios para ‘todos’ los programas que participan en estos.
Impacto generado por las prácticas empresariales desarrolladas por los estudiantes de ingeniería industrial de la Universidad de Santander - campus Bucaramanga, periodo: 2018 - 2022
Authors: Pérez Gutiérrez Pablo Andrés , Prada Pérez Viviana , Osses Abaunza Óscar Andrés
Published: October 2024

Las pasantías empresariales son un requisito indispensable en la Universidad de Santander UDES para obtener el título de ingeniero industrial, su propósito es complementar la formación académica del estudiante aplicando sus conocimientos y desarrollando habilidades enfocadas a soluciones efectivas en el entorno empresarial. Este proceso combina actividades académicas y laborales, proporcionando una oportunidad experimental supervisada por tutores académicos y empresariales. Desde luego, su principal objetivo es preparar a los estudiantes para su futuro profesional y contribuir así al desarrollo socioeconómico de la región santandereana y del país. Por lo tanto, este estudio cualitativo con enfoque descriptivo recolectó información directamente de las empresas y graduados que realizaron sus pasantías entre 2018 y 2022, permitiendo identificar aspectos referidos a sus experiencias de aprendizaje durante sus pasantías y oportunidades de mejora durante dicho proceso laboral, tanto desde el rol de los estudiantes pasantes como de las empresas que los vincularon. El objetivo del estudio fue determinar el impacto de las pasantías empresariales realizadas por los estudiantes de ingeniería industrial de la Universidad de Santander UDES, campus Bucaramanga, reconociendo las experiencias de aprendizaje, los conocimientos adquiridos de manera interinstitucional e interpersonal, y la influencia de dicha experiencia en la percepción de los estudiantes sobre el logro de los resultados de aprendizaje definidos por el programa académico. El estudio reveló un impacto positivo de las pasantías empresariales tanto en los estudiantes como en las empresas, principalmente enriqueciendo los perfiles profesionales de los futuros ingenieros industriales, dotándolos de competencias, habilidades y conocimientos en un contexto empresarial real, y contribuyendo con iniciativas modernas a la solución de dificultades organizacionales e incluso productivas en las empresas. Además, se destaca la colaboración y sinergia entre la institución de educación superior y el sector empresarial como elementos esenciales para la formación de los futuros profesionales y la relación efectiva de la universidad con el sector externo para promover una alta calidad académica, de acuerdo con los lineamientos del Consejo Nacional de Acreditación de Colombia (CNA).
Programación en sistemas robóticos de montaje de estructura matricial para producción multimodelo
Authors: Muñoz Guevara Jhon
Published: October 2024

El mercado actual exige productos cada vez más personalizados a precios de producción en masa, esto ha significado un enorme desafío para las industrias a nivel mundial, las cuales para mantenerse competitivas han innovado sus sistemas productivos para adaptarse a las condiciones de una demanda fluctuante, productos con ciclos de vida cortos, alta personalización y prontitud en la entrega. Los sistemas de producción se componen de tres etapas fundamentales, el diseño del producto, la manufactura y el ensamble. La planificación del ensamble es uno de los procesos más importantes en la fabricación de productos, ya que estos procesos consumen hasta el 50% del tiempo total de producción y más del 20% del costo total de fabricación. Los procesos de ensamble se pueden realizar en diferentes entornos como: estaciones de trabajo manuales, sistemas automáticos o sistemas robóticos. Los robots industriales contribuyen a que los procesos de ensamble tengan un elevado nivel de flexibilidad, por tal razón la implementación de robots en fábricas de todo el mundo ha tenido un incremento muy considerable en los últimos años. La introducción de robots en los procesos de ensamble proporciona mejoras en la productividad y la flexibilidad del sistema. No obstante, para lograrlo, es esencial abordar los problemas de la planeación y programación de las tareas de ensamble en estos sistemas. La personalización en masa ha impulsado a las industrias a adoptar sistemas de producción de pequeños lotes mediante el uso de sistemas de ensamble flexibles, como las líneas de ensamble de modelos mixtos o las celdas de ensamble robotizadas. Si bien la arquitectura en línea es eficiente para ensamblar grandes volúmenes de productos, carece de eficiencia cuando se requiere ensamblar diferentes productos. Por otro lado, las celdas de ensamble pueden manejar una amplia variedad de productos, pero debido a su diseño, son eficientes para la producción de lotes pequeños. Ante estas consideraciones, emerge una nueva arquitectura de ensamble conocida como el sistema de ensamble de estructura de matriz. En un contexto donde la demanda del mercado se inclina hacia una personalización creciente, los métodos de producción tradicionales quedan rezagados en términos de eficiencia. La estructura de matriz se postula como una solución que promete conjugar la producción a gran escala con la flexibilidad necesaria para ensamblar una amplia variedad de productos. Este enfoque innovador busca superar las limitaciones inherentes a las líneas y celdas de ensamble convencionales al ofrecer una solución híbrida. A pesar del notable aumento en la implementación de robots en fábricas a nivel mundial, la escasez de estudios específicos sobre sistemas de ensamble robotizados con estructura de matriz destaca la pertinencia y necesidad de una investigación más exhaustiva en este ámbito.
Extracción de características de señales biológicas longitudinales por medio de reconocimiento de patrones
Authors: Ramos Ledesma Diana Andrea , Gutiérrez Hernández David Asael , Zamudio Rodríguez Víctor Manuel , Lino Ramírez Carlos , Estrada Tolentino Karina
Published: October 2024

El estudio se centra en las dificultades que enfrentan las personas diagnosticadas con Trastorno del Espectro Autista (TEA) para comprender los pensamientos y emociones de los demás. A pesar del aumento significativo en los casos de TEA en los últimos años, en México no existen datos actualizados sobre su incidencia, aunque se estima que alrededor de 6,200 personas nacen con autismo cada año. Carol Ajax, fundadora de Spectrum Therapy Center México, señala que aproximadamente 1 de cada 115-120 personas en el país presenta algún tipo de trastorno del espectro autista. En el contexto actual de la tecnología, el reconocimiento de patrones juega un papel importante en la comparación de datos generados. Un patrón se define como una estructura o conjunto de características que se repiten en una secuencia o conjunto de datos. En el diagnóstico actual del TEA en niños, se emplean diversos test psicológicos para identificar una serie de características y comportamientos clínicos. El reconocimiento de patrones implica el uso de algoritmos computacionales para categorizar datos de entrada en diferentes objetos, clases o categorías según sus características predominantes o elementos consistentes. Esta técnica se aplica en varios campos, como visión por computadora, segmentación de imágenes, detección de objetos, procesamiento de datos de radar, reconocimiento de voz, clasificación de texto y otras áreas. Para llevar a cabo esta investigación, se empleará un dispositivo llamado diadema "Muse", diseñada específicamente para medir las señales cerebrales de manera similar a como lo hace un monitor de frecuencia cardíaca para detectar los latidos del corazón. Esta diadema inteligente está equipada con siete sensores que pueden detectar y medir la actividad cerebral, así como la frecuencia cardíaca del individuo. La justificación del estudio radica en la falta de pruebas específicas para determinar los métodos más eficientes de diagnóstico y tratamiento del TEA en cada paciente. Se sugiere que la medición de la frecuencia de las ondas cerebrales mientras el paciente se concentra podría proporcionar un apoyo significativo en el tratamiento, facilitando la identificación de enfoques más efectivos. Además, se argumenta que la recopilación de datos sobre las ondas cerebrales en personas con autismo podría contribuir al conocimiento científico sobre el trastorno, beneficiando así a la investigación en este campo.
Los juegos serios como estrategia educativa para la comprensión y adopción de comportamientos ambientales
Authors: Hoyos García Maria Camila , López Gómez Luisa Fernanda
Published: October 2024

Los problemas ambientales son, hace muchos años, centro de discusión, sin embargo, a pesar de la conciencia social sobre la gravedad de la situación aún hay mucho trabajo por hacer ya que, aunque se ha divulgado de muchas formas la necesidad de cuidar y cambiar los hábitos para disminuir el impacto ambiental, los resultados aún no son visibles. Por lo anterior, es relevante diseñar y usar herramientas que permitan más allá de educar, generar un cambio que contribuya a la reducción de los impactos sobre el medio ambiente (Bekoum, Essokolo y Robinot, 2022). Los juegos serios son una herramienta de enseñanza que tiene como finalidad un aprendizaje significativo sobre un centro temático y considerarla como estrategia que contribuya a educar y reducir los impactos ambientales, requiere conocerlos muy bien. Por lo anterior, es fundamental analizar a profundidad las publicaciones de juegos serios con enfoque ambiental, hecho que se efectúo para esta investigación en bases de datos especializadas. Este proceso, centro de la investigación, se llevó a cabo en Scopus y, de los resultados permitió identificar que el 77,3% de los juegos reportados son virtuales ya que, esta modalidad tiene beneficios como la accesibilidad a la herramienta, el rompimiento de las barreras de la distancia, una ágil divulgación y una aplicación práctica y sencilla del instrumento (Sermet et al., 2020 y Balois, 2018). Por lo anterior, se busca exponer cómo las diferentes dinámicas y consideraciones en el diseño de dichos juegos permiten que se conviertan en herramientas aplicables no solo en la comunidad educativa, sino en diversos sectores donde de manera individual y colectiva sirvan para desarrollar conocimientos y habilidades de gestión sobre las condiciones ambientales.
Extracción y purificación de creatininasa y creatinasa a partir de Pseudomonas putida para su aplicación en biosensores clínicos
Authors: Galindo de la Rosa Juan de Dios , González Regalado Héctor José , Pineda López Vanesa , Aldana Sánchez Ilse Yesamin , Vallejo Becerra Vanessa
Published: October 2024

En el presente trabajo se realizó la producción, extracción, separación y purificación de las enzimas creatininasa (EC 3.5.2.10) y creatinasa (EC 3.5.3.3) a partir de la bacteria Pseudomonas putida, microorganismo que ha tenido un interés creciente en el ramo de la investigación y la industria. La producción se indujo con creatinina 20 mM y medio LB para promover la formación de enzimas. Se observan cambios favorables en forma y velocidad de crecimiento de las colonias, indicando que la bacteria se ha adaptado al sustrato. Mediante el empleo de técnicas como precipitación de sulfato de amonio, diálisis y cromatografía líquida de alto rendimiento en su variante de intercambio aniónico, se logra la purificación y separación de las enzimas presentes en un mismo medio de cultivo. Se trabaja con una columna para intercambio aniónico High-Q. Se emplean ensayos enzimáticos para la detección óptica de actividad enzimática específica. Posterior a la etapa de cromatografía se logra obtener una actividad máxima de 1.69045 U/mg y factor de purificación de 3.3101 veces en la etapa de diálisis, para la enzima creatininasa; mientras que para la creatinasa se logra una actividad de 1.1256 U/mg con factor de purificación de 4.8430 después de cromatografía. Los rendimientos obtenidos fueron de 0.0099% y 0.0638 % para las enzimas creatininasa y creatinasa, respectivamente. Estas enzimas forman parte de las reacciones en cadena de la ruta de degradación de la creatina. La creatinina y creatina han tomado relevancia como biomarcadores para diversas patologías, y funcionan como indicadores de diversas funciones corporales, entre ellas la función renal y muscular. La detección directa de creatinina no es posible. Es por ello que la ruta enzimática se ha empleado como un método de detección indirecto confiable, debido a la alta especificidad de las enzimas. La producción de enzima nativa dentro del laboratorio de trabajo permitirá apoyar en trabajos de desarrollo de biosensores de aplicación médica para la detección de creatinina y creatina, y trabajos de multisensado. La disponibilidad de enzima nativa permitirá agilizar y economizar el trabajo de investigación en diversos proyectos.
Dimension of Attitudes in Flipped Learning: Enjoyment, Engagement, Motivation, Behavioral Intention, and Perception
Authors: Oya Abas , Parmiti Desak Putu , Jampel I Nyoman , Candiasa I Made , Susilawati Aay
Published: October 2024

This research investigates the influence of video-based flipped learning on the attitudes of students in non-English language programs, focusing on enjoyment, engagement, motivation, behavioral intentions, and perception. The study employed a descriptive research design, collecting data through questionnaires administered to 30 students enrolled in non-English language courses. The findings reveal a significantly positive attitude towards flipped learning, with high scores in enjoyment and engagement indicating a preference for the interactive and dynamic nature of video-based learning environments. The study confirms that motivation and behavioral intentions are positively affected by the flipped model, enhancing students' proactive learning behaviors and overall engagement with the course material. Moreover, the positive perception of video-based learning among students suggests that this method supports a deeper understanding and retention of language skills. This research contributes to the educational discourse by demonstrating that flipped learning models can significantly improve learning experiences and outcomes in non-English language settings. Future studies are encouraged to explore the long-term impacts of flipped learning on language proficiency and retention, aiming to validate and expand upon the current findings.
ON THE PROBLEMS OF CALCULATING THE EFFECTIVE THERMAL CONDUCTIVITY OF MULTILAYER STRUCTURES AND THE CONTACT THERMAL RESISTANCE OF INTERFACES
Authors: Barinov Aleksandr , Khvesyuk Vladimir
Published: October 2024

One of the key problems of calculating the intensity of heat transfer in solid-state micro- and nanostructures is the boundary effect. The boundary effect is associated, firstly, with the morphology of the real surface of the sample (surface roughness and etc) and, secondly, with the significant influence of the interaction of heat carriers with the sample boundary. Approaches to the integrated consideration of the boundary effect in calculating the effective thermal conductivity of films and the contact thermal resistance of interfaces are proposed.
THREE-SCALE MODELING AND THE TERMS OF C-SYSTEMS: THE EXAMPLE OF A UV RADIATION SENSOR BASED ON ZINC OXIDE NANORODS
Authors: Matyushkin Igor
Published: October 2024

The relevance of using the С-systems formalism as a tool for implementing three-scale models is shown. Methodological issues are considered on the example of a matrix structure based on a 1D-nanomaterial.
APPLICATION OF DIGITAL TWINS TO THE IMPLANTABLE MICROELECTRONIC SYSTEMS RELIABILITY ISSUE
Authors: Mindubaev Eduard
Published: October 2024

The paper describes the results of designing a prototype of a digital twin of an inductive energy transfer system for an implantable medical device. The digital twin is based on a mathematical model for calculating the electrical characteristics of the system, as well as finite element models for assessing the heating and electrical characteristics of the inductance coils.
PENGEMBANGAN MODUL AJAR BERBASIS PMRI MENGGUNAKAN KONTEKS PASAR INPRES LUBUKLINGGAU PADA MATERI ARITMATIKA SOSIAL KELAS VII
Authors: Selviyani Anggi , Refianti Rani , Purwasi Lucy Asri
Published: October 2024

This study aims to produce PMRI-based teaching modules using the market context of Inpres Lubuklinggau on class VII social aritamtics material that is valid, practical, and has potential effects. This research is a development research using the ADDIE development model, which consists of stages: analysis, design, development, implementation and evaluation. Data collection techniques were carried out through interviews, observations, questionnaires, and tests, with the subjects of the study being grade VII students of SMPIT Mutiara Cendekia Lubuklinggau totaling 6 students for the small group test and 24 students for the field test. Based on the results of data analysis, it shows that Aiken's V value from the validation of linguists is 0.85, media experts are 0.83 and material experts are 0.81 with very valid categories. In the practicality test, teachers and students obtained an overall percentage of 85.34% in the very practical category. And the results of the potential effect test through tests given by 24 students obtained data that 21 students (88%) were included in the complete category and 3 students (12%) with the incomplete category.
PENGARUH PEMBELAJARAN MATEMATIKA BERBASIS PROYEK TERHADAP KEMAMPUAN PEMECAHAN MASALAH SISWA KELAS X SMAN 1 PEGAJAHAN
Authors: Fadhilla Yuka , Afri Lisa Dwi
Published: October 2024

This study aims to examine the impact of Project-Based Learning (PjBL) on the problem-solving abilities of tenth-grade students at SMA Negeri 1 Pegajahan within the context of the Merdeka Curriculum. The research employs a quantitative method with a quasi-experimental approach, utilizing a Pretest-Posttest Only One Group Design. The population includes all tenth-grade students, with samples selected using Cluster Random Sampling techniques. Data were collected through pretests and posttests and analyzed using descriptive and inferential statistical tests, including normality tests, homogeneity tests, and the Paired Sample t-Test. The results indicate a significant improvement in students' problem-solving abilities following the implementation of PjBL. The t-test results demonstrate a positive effect of PjBL on students' problem-solving skills. Based on these findings, it is concluded that PjBL is an effective teaching method for enhancing students' mathematical problem-solving abilities. This study provides valuable contributions to the development of more innovative and relevant teaching methods, particularly in supporting the implementation of the Merdeka Curriculum in Indonesia.
RELEVANCE OF BUDDHISM IN MODERN WORLD
Authors: Dan Ishwar
Published: October 2024

The core message of Buddhism centers around peace and integrity. Buddhism is regarded as a practical religion of peace and non-violence. Non-violence is a way of life free from extremes of passion, such as anger, hostility, pleasure, and pain. The principle of non-violence upholds the ideal of universal peace. We come from the land of Buddha, not from the land of War (Yuddh). “Buddhism is not just a religion of the past or a mere faith as many have thought, but it is a time-tested scientific religion and philosophy which, in the context of the present world-situation, is more relevant today than ever before for establishing world peace . In the 21st century, Buddhists have the responsibility to rediscover how their tradition of Ahimsa, love, and compassion can help individuals achieve peace in their own lives and within the global community.
ROLE OF INDEPENDENT DIRECTORS IN MITIGATING FINANCIAL STATEMENT FRAUD: INSIGHTS
Authors: Arora Deepika , Sharma Renuka , Mehta Kiran
Published: October 2024

The role of independent directors has gained increasing attention in corporate governance, particularly in their ability to mitigate financial statement fraud. This study investigates the relationship between board independence and the likelihood of financial fraud within Indian companies, using the Altman Z-score as a measure of financial health. The analysis explores how the proportion of independent directors on corporate boards impacts fraud detection and prevention, alongside other board attributes such as audit committee size, board size, and gender diversity. The findings suggest that a higher proportion of independent directors significantly reduces the likelihood of financial misreporting, enhancing transparency and accountability. The results highlight the critical governance role of independent oversight, emphasizing the need for stringent regulations and best practices to strengthen board independence in safeguarding financial integrity. These insights contribute to ongoing discussions on corporate governance reforms and provide practical recommendations for firms and policymakers to reduce fraud risk in emerging markets like India.
THE FRAMEWORK OF NEOCOLONIAL RUDIMENTS IN CHINUA ACHEBE’S ANTHILLS OF SAVANNAH
Authors: T. R. Deepak , Naveen. S.
Published: October 2024

Literature is observed as a serious and systematic mechanism to manuscript the tranquilities of human endeavours. The diversified domain of Africa is superlatively known for culture, rituals, heritage, tradition and wild life. These diversities have become the integral element of common folk who inhabit and experience the predicaments of African humanity. Most of the nations in African continent are under the silhouette of colonial inheritance even after attaining sovereignty. The literature of Africa has been instrumental in documenting the transformations perceived at different altitudes. It unlocks an option for authors to embody the boons and banes of African citizens. Writers like Ngugi wa Thiong’o, Nadine Gordimer, Chimamanda Ngozi Aichie and Chinua Achebe have focused on both the abstract and concrete rudiments of African social order.Chinua Achebe is clinical and influential in typifying the standards of African civilization. He is embarked as a literary figure that represents the African verve in a lucid and sober manner. His literary exposition Anthills of Savannah (1987) traces the life of colonized populace in Africa. With the consequence of colonization, both the individuals and homeland have lost the dignity and integrity. The novelist tries to reclaim the lost dignity for the betterment of Africa through this literary description. But the political leaders fail to restore the dignity of Kangan in Africa. In turn they continue to exist as the substance of white colonizers. The period after colonialism is called ‘Postcolonialism’ and it is also termed as ‘Neocolonialism’. Hence, the research paper makes an attempt to study the framework of neoclassical rudiments in Chinua Achebe’s Anthills of Savannah within the obtainable charter.
Mi’kmaw-Owned Partnership in Clearwater Seafoods
Authors: Doucette Mary Beth , Stack Ryan
Published: October 2024

The keynote presentation at the 2023 Cando Annual Conference focused on telling the story of the acquisition of Clearwater Seafoods by the Mi'kmaw Consortium and Premium Brand Seafoods. It highlighted a Mi’kmaw corporate perspective of the acquisition, co-presented Mike McIntyre, Membertou CFO, Jenny Morgan, Clearwater Seafoods LP, Darryl McDonald, CAO Paqtnkek Mi'kmaw Nation. This lesson from experience submission is a summary of their presentation which focused on three core aspects of the deal. First was the messaging around building business relationships. The endeavor was only possible because Membertou had a reputation for being community minded, trustworthy, and professional. Second, the deal was crafted to minimize risk to pre-existing community assets the deal would not hurt the borrowing potential of the coalition communities in the near or distant future. Finally, the presentation highlighted the opportunities for Clearwater to expand through strategic innovation. Although Premium Brands was not represented in the presentation, the explanation of their role in the partnership highlights the potential for strategic innovation in the future.
A Study on the Deep Learning Model for Autonomous Vehicle Driving
Authors:   Korean Industrial Technology Convergence Society, Ha Sungjae , Moon ByoungJoon
Published: October 2024

The purpose of this study was to investigate deep learning models for indoor autonomous vehicles. Deep learning was conducted using an NVIDIA model, transfer learning models, and the CNN model developed in this study, and the MAE and R2-score values were compared. The results demonstrated that both the NVIDIA model and the proposed CNN model exhibited not only stable loss values but also superior R2-score characteristics. By contrast, the transfer learning model did not achieve stable loss or R2-score values. Based on the results of the modified model, this study proposed a CNN model that is comparable to a GPU-based NVIDIA model.
Optimizing Nitrification in Landfill Leachate Treatment: Effects of pH and Inorganic Carbon Source Concentration on Nitrogen Removal
Authors:   Korean Industrial Technology Convergence Society, Yang Jang-Hoon , Park Jin-Young
Published: October 2024

This study was conducted to solve problems that arise in the nitrification of landfill leachate due to the increase in waste generation and diversification of components associated with domestic economic growth. Landfill leachate contains high concentrations of nitrogen compounds and organic substances thus, it is a potential cause of environmental pollution. The study findings confirmed that the nitrification process was inhibited when the metal (Cu) concentration was more than 2.5ppm: further, the nitrification rate could be greatly improved by replenishing alkalinity and adjusting pH. Additionally, appropriate Do and pH alone did not have a sufficient effect on nitrification. This study is expected to contribute to the development of new treatment technology that can minimize the use of chemicals and suppress the generation of secondary toxic substances in the landfill leachate treatment process.
Action Research for Establishing Corporate Culture via a Culture Deck in an M&A Company
Authors:   Korean Industrial Technology Convergence Society, Ok Kwang-Hee , Ahn Ji-Ahn
Published: October 2024

Based on action research, this study aims to determine the manner by which a newly established company formed via merger and acquisition establishes their unique corporate culture by creating a “culture deck” and infusing it into employees’ daily lives through culture activities led by the culture project team. To create a culture deck, comprehensive interviews were performed on “C”-level executives, after which the results were transcribed and coded for categorization. The culture deck was drafted based on the interviews and then complemented by focus-group interviews with middle managers. Finally, all employees participated in an online live session for a culture jam to provide their feedback regarding the culture deck. The culture deck includes the company’s vision, mission, leadership principles, compliance commitments, and detailed culture guide for decision making. To normalize the culture deck in the workplace, the company formed a culture task-force team and implemented various entertaining culture activities for promotion. The process of constructing a culture deck can be easily applied to other companies, thus facilitating them in establishing and fostering their own corporate culture.
Effect of Welding Process of the Microstructure and Mechanical Properties of Weld Zone of Steel for Ship Structure B Gr. Steel
Authors:   Korean Industrial Technology Convergence Society, Kwon Soon-Doo , Jeong Sang-Hoon
Published: October 2024

The microstructurale and mechanical properties of B Gr. steel were evaluated for shipbuilding according to a welding process. The following conclusions were drawn. In tandem submerged arc welding(TSAW), compared to single submerged arc welding(SAW), the grain boundary ferrite was coarsened, and the fraction was higher owing to the high heat input and low flux basicity ; conversely, the volume fraction of acicular ferrite was lower. Fine intragranular acicular ferrite and polygonal ferrite were observed in the weld metal of the electrogas welding (EGW), which had the highest heat input. In the microstructure near the fusion line, as the amount of heat input increased, the prior austenite grain boundary became coarse. Further, both the intergranular grainboundaryferrite and intragranular bainite became coarse, and the heat-affected zone became wider. The hardness of weld metal was independent of the amount of heat input and was demonstrated to be high in the order of EGW, single SAW, and TSAW owing to the microstructure difference caused by the chemical composition of the filler material and the dilution rate of the base metal. Furthermore, the tensile strength of all three welding processes resulted in stable satisfaction with the class society rules.