bluuebunny/crossref_metadata_2025 huggingface dataset:
In silico identification of natural compounds from virgin coconut oil as potential ligand peroxisome proliferator-activated receptor-gamma as preventive food leads against colitis
Authors: Rika Trismayanti Ni Made , Kusworini  , Dian Handayani
Published: April 2023

Ulcerative colitis (UC) is an inflammation of the large intestine characterized by diarrhea with blood. UC has a more extensive manifestation in children. Current therapy has not given satisfactory results. This is the basis for the need for preventive therapy to reduce the morbidity and mortality of UC in children. Virgin coconut oil (VCO) is a viable dietary supplement option due to its ability to act as a peroxisome proliferator-activated receptor (PPAR) ligand, inhibiting the release of pro-inflammatory cytokines. The aim of this study was to determine natural compounds from VCO that have the potential to prevent colitis using a docking-based virtual screening approach. Quantitative structure-activity relationship analysis was used to find out how similar the input compounds and the database were. Docking is done using AutoDockTools 1.5.6. The algorithm used is the Lamarckian Genetic Algorithm (4.2). PPAR-gamma (PPAR-γ) was used as the target protein in a complex with rosiglitazone (ID PDB: 7AWC). PyMol 2.5.1 was used to prepare and visualize three-dimensional data, and the amino acid interactions were visualized using Discovery Studio 2021 Clients. It was found that linoleic acid and oleic acid in VCO have anti-inflammatory effects with predictive values of 0.73 and 0.614, respectively, and that they stop tumor necrosis factor (TNF) expression with predictive values of 0.751 and 0.724. The result of molecular docking showed that the VCO compound was able to interact with the same residue as the control. VCO reduces inflammation by acting as a PPAR-γ and TNF expression inhibitor.
Increasing the stability of incense gum extract (Styrax benzoin) with a mixture of surfactants
Authors: Susanti Nora , Purba Jamalum , Gopas Oetama M. Yosia
Published: April 2023

Styrax benzoin is a type of incense produced in North Tapanuli, Indonesia. The content of metabolite compounds provides wide use in pharmaceuticals. The occurrence of deposits in the extract makes this preparation unstable; this instability creates problems, especially in the concentration of the extract and is impractical so it needs to be redissolved. The method of using surfactants can be used as a suspending agent, a mixture of two types of surfactants gives variations in hydrophilic and lipophilic balance (HLB), by finding the optimum HLB value to create optimum solution stability and organoleptic, various mixture ratios were carried out with test parameters such as organoleptic, pH, viscosity, particle size, and components of chemical compounds. The results show that the optimum HLB of S. benzoin is 12.7 in surfactants Tween 80 and Span 80.
Synthesis of nitrogen mustard-based fluorophores for cell imaging and cytotoxicity studies
Authors: Liang Yuanwei , Liang Maojun , Li Cuiyu , Wang Daini , Gong Xiaoxuan , Zheng Kaiji
Published: April 2023

Nitrogen mustards are important alkylating anticancer drugs used for neoplasms treatment. However, little research about the integration of luminophore into nitrogen mustard-based compounds for both imaging and therapeutic application was reported. In this study, we report a series of novel nitrogen mustard-containing 1-furyl-2-en-1-one and 1-thienyl-2-en-1-one derivatives as intramolecular charge transfer-based luminophore for research in both imaging subcellular localization and antiproliferation toward lung cancer cells. The target products were prepared by Knoevenagel condensation and characterized by nuclear magnetic resonance and high-resolution mass spectrometer. The absorption and fluorescence studies were carried out by ultraviolet-visible and fluorescence spectrophotometers, respectively. Cell morphology was observed under an inverted microscope. Cytotoxicity test was detected by MTT assay. Cellular localization was observed by a confocal laser scanning microscope. Colony formation ability was carried out by colony formation assay. Cell migration ability was detected by transwell migration assay. Differences between the two groups were analyzed by two-tailed Student's t-test. The difference with P < 0.05 (*) was considered statistically significant. The compounds were synthesized in high yield. The λmax and Stokes shift of these compounds reach up to 567 and 150 nm, respectively. These compounds exhibited good antiproliferative activity against lung cancer cells, with compound 3h exhibiting the best IC50 of 13.1 ± 2.7 μM. Furthermore, the selected compound 3h is located preferentially in lysosomes and a small amount in nuclei, effectively inhibiting cell colony formation and migration abilities toward A549 cells. These findings suggested that nitrogen mustard-based fluorophores might be a potential effective chemotherapeutic agent in lung cancer therapy.
Assessment of Long-Term Sequelae of Pulmonary Dysfunction Associated with COVID-19 Using Pulmonary Pulse Transit Time
Authors: Duran Mustafa , Uygun Turgut , Kurtipek Ercan
Published: April 2023

Background:

Studies report deleterious impacts of severe acute respiratory syndrome coronavirus 2 on multiple organs in the human body, not only in the acute infection period but also in the long-term sequelae. Recently defined pulmonary pulse transit time (pPTT) was found to be a useful parameter regarding the evaluation of pulmonary hemodynamics. The purpose of this study was to determine whether pPTT might be a favorable tool for detecting the long-term sequelae of pulmonary dysfunction associated with coronavirus disease 2019 (COVID-19).

Materials and Methods:

We evaluated 102 eligible patients with a prior history of laboratory-confirmed COVID-19 hospitalization at least 1 year ago and 100 age- and sex-matched healthy controls. All participants’ medical records and clinical and demographic features were analyzed and underwent detailed 12-lead electrocardiography, echocardiographic assessment, and pulmonary function tests.

Results:

According to our study, pPTT was positively correlated with forced expiratory volume in the 1st s, peak expiratory flow, and tricuspid annular plane systolic excursion (r = 0.478, P < 0.001; r = 0.294, P = 0.047; and r = 0.314, P = 0.032, respectively) as well as negatively correlated with systolic pulmonary artery pressure (r = −0.328, P = 0.021).

Conclusion:

Our data indicate that pPTT might be a convenient method for early prediction of pulmonary dysfunction among COVID-19 survivors.
The Utility of Paraspinal Acoustic Windows for the Evaluation of Acute Dissection of Descending Thoracic Aorta in the Emergency Setting
Authors: Conti Serenella , Dell’Uomo Marco , Dominici Marcello , Forte Maria Beatrice
Published: April 2023

Acute aortic dissection (AAD) is the prevalent acute aortic syndrome characterized by rapid onset and progression with time-dependent prognosis. When suspecting AAD of descending thoracic aorta in the context of the emergency department setting, computed tomography scanning and trans-esophageal echocardiography are the most useful imaging modalities. The sensitivity of transthoracic echocardiography in diagnosing for type B dissection is only 31%–55% when compared with other modalities. We describe the case of a 62-year-old female with a clinical history of Marfan syndrome where the low sensitivity of the transthorac approach in the detection of descending aortic dissection was overcomed by the posterior thoracic approach with the posterior paraspinal window (PPW). In the literature, are described just few reports where echocardiography via the PPW makes it possible to diagnose acute descending aortic syndrome.
Large Serpiginous Thrombus Crossing a Patent Foramen Ovale
Authors: Ermacora Davide , Engl Patrick , Milewski Priscilla , Casablanca Simona , Cemin Roberto
Published: April 2023

Transesophageal iconic image of a large serpiginous thrombus crossing a patent foramen ovale.
Very Mobile Left Ventricular Outflow Tract Papillary Fibroelastoma Presenting with Multiple Ischemic Strokes
Authors: Barbarossa Alessandro , Coraducci Francesca , Cipolletta Laura , Guerra Federico , Russo Antonio Dello
Published: April 2023

Papillary fibroelastomas (PFs) are small and pedunculated left side valves associated mass, that frequently causing cerebral embolization. We present the case of a 69-year-old male with a history of multiple ischemic strokes and a small pedunculated mass in the left ventricle outflow tract, highly suggestive of a rare case of PF in an atypical localization. Due to the clinical history and the echocardiographic aspect of the mass, he underwent surgical excision and Bentall intervention for concomitant aortic root and ascending aorta aneurysm. The pathological analysis of the surgical specimen confirmed the diagnosis of PF.
Association between Right Ventricle–Pulmonary Artery Coupling with In-Hospital Outcome after Triple Valve Surgery in Rheumatic Heart Disease
Authors: Soesanto Amiliana Mardiani , Hendiperdana Mochamad Rizky , Zahara Rita , Tjubandi Amin , Juzar Dafsah , Iryuza Nanda , Siagian Sisca Natalia
Published: April 2023

Context:

Triple valve surgery (TVS) is a relatively higher in-hospital mortality rate than any isolated valve surgery. In advanced-stage valvular heart disease, maladaptation may occur, creating RV-PA uncoupling. Aims To evaluate whether RV-PA coupling is associated with the in-hospital outcome of patients after TVS.

Settings and Design:

From the medical records, clinical and echocardiography data were collected and compared between the survived and patients with in-hospital mortality groups.

Methods and Material:

Patients with the rheumatic multivalvular disease who underwent triple valve surgery were included in the study. Statistical and analysis used Uni and bivariate analysis assessed any association between the RV-PA coupling using TAPSE/PASP and other clinical variables with the in-hospital mortality post TVS.

Result:

From 269 patients, the in-hospital mortality rate was 10 %. The median value of TAPSE/PASP ratio in all group is 0.41 (0.02-5.79). Impaired RV-PA coupling which value < 0.36 occurs in 38.3 % population. By multivariate analysis, independent predictors of in-hospital mortality were TAPSE/PASP < 0.36 (OR 3.46, 95 % CI 1.21 – 9.89; P 0.02), age (OR 1.04, 95 % CI 1.003-1.094; P 0.035), CPB duration, (OR 1.01, 95 % CI 1.003-1.017; P 0.005).

Conclusion:

RV-PA uncoupling assessed by TAPSE / PASP ratio < 0.36 is associated with the in-hospital mortality in patients post triple valve surgery. Other factors associated with the outcome were older age and longer CPB machine duration.
Laparoscopic management of colovesical fistula in different clinical scenarios
Authors: Campobasso Davide , Zizzo Maurizio , Biolchini Federico , Castro-Ruiz Carolina , Frattini Antonio , Giunta Alessandro
Published: April 2023

Introduction:

Colovesical fistula (CVF) is a condition with various aetiologies and presentations. Surgical treatment is necessary in most cases. Due to its complexity, open approach is preferred. However, laparoscopic approach is reported in the management of CVF due to diverticular disease. The aim of this study was to analyse the management and outcome of patients with CVF of different aetiologies treated with laparoscopic approach.

Patients and Methods:

This was a retrospective study. We retrospectively reviewed all patients undergoing elective laparoscopic management of CVF from March 2015 to December 2019.

Statistical Analysis Used:

None.

Results:

Nine patients underwent laparoscopic management of CVF. There were no intraoperative complications or conversions to open surgery. A sigmoidectomy was performed in eight cases. In one patient, a fistulectomy with sigmoid and bladder defect closure was performed. In two cases of locally advanced colorectal cancer with bladder invasion, a multi-stage procedure with temporary colostomy was chosen. In three cases, with no intraoperative leakage, we did not perform bladder suture. Four Clavien I–II complications were recorded. Two fragile patients died in the post-operative period. No patients required re-operation. At a median follow-up of 21 months (interquartile range: 6–47), none of the patients had recurrence of fistula.

Conclusions:

CVF can be managed with laparoscopic approach by skilled laparoscopic surgeons in different clinical scenarios. Bladder suture is not necessary if leakage is absent. Informed counselling to the patient must be guaranteed concerning the risk of major complications and mortality in case of CVF due to malignant disease.
Binucleate Cells in Cytosmears
Authors: Priyadharshini Gayathri , Phansalkar Manjiri , Ambroise Moses , Ramdas Anita
Published: April 2023

Background:

Although the classic Reed-Sternberg (RS) cell is considered a diagnostic of Hodgkin's disease, RS-like cells have been noted in various benign and malignant conditions. The presence of these cells can be a diagnostic challenge.

Aims:

Our aim was to see if cells morphologically resembling or identical to RS cells occur in conditions other than Hodgkin lymphoma (HL) and what proportion of cases show binucleate cells in various benign and malignant conditions. We also want to discuss the diagnostic utility of cytomorphological features in predicting HL.

Material and Methods:

This study is a retrospective analysis of 2086 cytology cases. The cytosmears were screened for the presence of binucleate cells. A detailed cytomorphological analysis of cytosmears with binucleate cells was performed, and the diagnostic utility of cytomorphological criteria in delineating HL was examined.

Results:

Out of 2086 smears, 55 (2.6%) cytosmears showed binucleated RS/RS-like cells. Out of these 55 cases, 6 were HL, 3 cases were non-HL (NHL), 3 were sarcoma, 32 were carcinoma, and 11 were benign/inflammatory lesions. The presence of prominent eosinophilic nucleoli, granulomas, and eosinophils had good sensitivity and specificity in predicting the diagnosis of HL.

Conclusion:

A detailed cytomorphological analysis is of limited value in categorizing the RS and RS-like cells. However, few cytomorphological features such as prominent eosinophilic nucleoli, eosinophils, granulomas, and lack of clustering of atypical cells can help us in predicting HL.
Application of Indian Academy of Cytologists Guidelines for Reporting Serous Effusions
Authors: Kundu Reetu , Srinivasan Radhika , Dey Pranab , Gupta Nalini , Gupta Parikshaa , Rohilla Manish , Gupta Shruti , Bal Amanjit , Rajwanshi Arvind
Published: April 2023

Background:

Recently, the Indian Academy of Cytologists (IAC) has published the guidelines for interpretation and reporting of serous effusions. Till date, there are no studies on its applicability.

Aims:

The present study was carried out to assess the feasibility of applying the IAC reporting categories to effusions, determine the frequency, and provide an estimate of the risk of malignancy (ROM) for individual diagnostic categories.

Materials and Methods:

All cases of serous effusion fluids reported in the year 2019 were retrieved from the archives and reassigned as per the IAC diagnostic categories. The clinical and histopathological follow-up information was obtained wherever possible.

Results:

A total of 1340 effusion samples were received from 1085 patients. There were 561 (51.7%) males and 524 (48.3%) females. Majority were pleural (1066, 79.5%), followed by peritoneal (187, 14%) and pericardial (87, 6.5%) effusions. The age ranged from 7 months to 92 years. There were 35 (2.6%) samples in category 1 (non-diagnostic), 954 (71.2%) in category 2 (benign), 17 (1.3%) in category 3 (atypical), 59 (4.4%) in category 4 (suspicious for malignancy) and 275 (20.5%) in category 5 (malignant). The estimated ROM in serous effusion samples was 20% for category 1, 16.7% for category 2, 50% for category 3, 94.4% for category 4 and 100% for category 5.

Conclusions:

The categorization of serous effusion cytology samples as per the IAC diagnostic categories and as per the reporting format developed by the IAC is feasible and the management recommendations are mostly appropriate.
Efficacy and Validity of Image-Guided Percutaneous Fine Needle Aspiration and Core Biopsy of Liver Pathologies
Authors: Rai Santosh Phajir Vishwanath , Kumar Vinay KM , Basavaiah Sridevi Hanaganahalli , Sreeram Saraswathy , Gopal Sandeep , Tantry Bailuru Vishwanath
Published: April 2023

Context:

Radiology and pathology are pivotal tools in the investigational artillery for management of wide spectrum of hepatic lesions and early detection is of a paramount importance.

Aims:

The study aimed at analyzing the efficacy, comparative yield and validity of image-guided aspiration cytology (FNA)/core biopsy (CB) in focal hepatic lesions.

Settings and Design:

A retrospective hospital-based study was conducted in departments of Pathology and Radiology and Imaging of a tertiary care center.

Materials and Methods:

Cases of focal hepatic lesions that underwent percutaneous image guided-FNA reported (2011-2018) were analyzed. Cytological-histopathological correlation was performed where available. FNA diagnoses were divided into four categories-positive for malignancy (group 1), atypical (group 2), negative for malignancy (group 3), and non-diagnostic (group 4).

Statistical Analysis Used:

Categorical data was depicted in the form of frequencies and proportions. Validity of percutaneous image-guided FNA diagnosis was collated with the final diagnosis and results were analyzed.

Results:

A total of 338 FNA of focal hepatic lesions were reported in which 217 (68.2%) cases in group 1; 21 (6.2%) in group 2; 58 (17.2%) in group 3 and 42 (12.4%) in group 4. CB correlation was available in 123 cases. Based on clinical, radiological and pathological findings, conclusive final diagnoses were obtained and the cases were regrouped [malignant cases-245, benign lesions-57 and uncertain lesions-36]. Metastasis was the most common malignancy (175/245; 71.4%). Sensitivity, specificity, and overall diagnostic accuracy of FNA to categorize the lesion as benign or malignant were 96.94%, 100% and 97.51%, respectively. However, the cytology-histopathology correlation revealed discordance of subtyping the lesion in 20% of cases and sensitivity and specificity reduced to 80% and 50% respectively in rendering the specific diagnosis.

Conclusions:

Percutaneous image-guided FNA is a sensitive and specific tool with high diagnostic accuracy in evaluating focal hepatic lesions. The study highlights the pre-eminence of interventional radiology and cytology in the care of patients with liver lesions.
Mental Health Evaluation and Assistance for Visually Impaired People
Authors: Pandey Kavita , Pandey Dhiraj
Published: April 2023

Earlier, three-person out of every 10 persons had been suffering from mental health issues but nowadays this situation became worsened due to the pandemic. The number of individuals suffering from mental health has been increasing day by day. One of the WHO reports states that 3.8% of the population has been affected due to depression. Although such an important issue in human health, still it is one of the neglected health sectors around the world. This situation is more worsened among special need people as they feel more anxiety disorders and loneliness in comparison to their sighted peers. Technology is helping us to solve several such problems which are difficult to discuss with peers and worsen over time if not taken preventively on time. In this article, a technological solution using facial expression and voice-based assistance has been used. This would especially help in monitoring the mood of visually challenged people.  Their mental health can be monitored and assistance would be provided as per the severity of the situation. Mental health is analyzed based on emotion recognition from facial expressions and psychometric evaluations. A health score would be calculated which is used to judge the severity of mental health. An assessment report would also be generated and sent to the guardian of the user. The whole application is designed with a voice assistance platform using Dart (Flutter) and firebase as storage for all interactions with the visually challenged person.
On spatial conditioning of the spectrum of discrete Random Schrödinger operators
Authors: Gaudreau Lamarre Pierre Yves , Ghosal Promit , Liao Yuchen
Published: April 2023

Consider a random Schrödinger-type operator of the form

H:=-H_X+V+\xi

acting on a general graph

\mathscr{G}=(\mathscr {V},\mathscr{E})

, where

H_X

is the generator of a Markov process

X

on

\mathscr{G}

,

V

is a deterministic potential with sufficient growth (so that

H

has a purely discrete spectrum), and

\xi

is a random noise with at-most-exponential tails. We prove that the eigenvalue point process of

H

is number rigid in the sense of Ghosh and Peres (2017); that is, the number of eigenvalues in any bounded domain

B\subset\mathbb{C}

is determined by the configuration of eigenvalues outside of

B

. Our general setting allows to treat cases where

X

could be non-symmetric (hence

H

is non-self-adjoint) and

\xi

has long-range dependence. Our strategy of proof consists of controlling the variance of the trace of the semigroup

\mathrm{e}^{-t H}

using the Feynman–Kac formula.
The fate of Landau levels under $\delta$-interactions
Authors: Behrndt Jussi , Holzmann Markus , Lotoreichik Vladimir , Raikov Georgi
Published: April 2023

We consider the self-adjoint Landau Hamiltonian

H_0

in

L^2(\mathbb{R})

whose spectrum consists of infinitely degenerate eigenvalues

\Lambda_q

,

q \in \mathbb{Z}_+

, and the perturbed Landau Hamiltonian

H_\upsilon = H_0 + \upsilon\delta_\Gamma

, where

\Gamma \subset \mathbb{R}

is a regular Jordan

C^{1,1}

-curve and

\upsilon \in L^p(\Gamma;\mathbb R)

,

p>1

, has a constant sign. We investigate

\operatorname{ker}(H_\upsilon -\Lambda_q)

,

q \in \mathbb{Z}_+

, and show that generically

0 \leq \operatorname{dim\ ker}(H_\upsilon -\Lambda_q) - \operatorname{dim ker}(T_q(\upsilon \delta_\Gamma)) < \infty,

where

T_q(\upsilon \delta_\Gamma) = p_q (\upsilon \delta_\Gamma)p_q

, is an operator of Berezin–Toeplitz type, acting in

p_q L^2(\mathbb{R})

, and

p_q

is the orthogonal projection onto

\operatorname{ker} (H_0 -\Lambda_q)

. If

\upsilon \neq 0

and

q = 0

, then we prove that

\operatorname{ker} (T_0(\upsilon \delta_\Gamma)) = 0

. If

q \geq 1

and

\Gamma = \mathcal{C}_r

is a circle of radius

r

, then we show that

\operatorname{dim\ ker}(T_q(\delta_{\mathcal{C}_r})) \leq q

, and the set of

r \in (0,\infty)

for which

\operatorname{dim\ ker}(T_q(\delta_{\mathcal{C}_r})) \geq 1

is infinite and discrete.
Coverings preserving the bottom of the spectrum
Authors: Polymerakis Panagiotis
Published: April 2023

We prove that if a Riemannian covering preserves the bottom of the spectrum of a Schrödinger operator, which belongs to the discrete spectrum of the operator on the base manifold, then the covering is amenable.
Cheeger estimates of Dirichlet-to-Neumann operators on infinite subgraphs of graphs
Authors: Hua Bobo , Huang Yan , Wang Zuoqin
Published: April 2023

In this paper, we study the Dirichlet-to-Neumann operators on infinite subgraphs of graphs. For an infinite subgraph, we prove Cheeger-type estimates for the bottom spectrum of the Dirichlet-to-Neumann operator, and the higher order Cheeger estimates for higher order eigenvalues of the Dirichlet-to-Neumann operator.
On the spectrum of the periodic focusing Zakharov–Shabat operator
Authors: Biondini Gino , Oregero Jeffrey , Tovbis Alexander
Published: April 2023

The spectrum of the focusing Zakharov–Shabat operator on the circle is studied, and its explicit dependence on the presence of a semiclassical parameter is also considered. Several new results are obtained. In particular: (i) it is proved that the resolvent set is comprised of two connected components; (ii) new bounds on the location of the Floquet and Dirichlet spectra are obtained, some of which depend explicitly on the value of the semiclassical parameter; (iii) it is proved that the spectrum localizes to a “cross” in the spectral plane in the semiclassical limit. The results are illustrated by discussing several examples in which the spectrum is computed analytically or numerically.
The wave trace and Birkhoff billiards
Authors: Vig Amir
Published: April 2023

The purpose of this article is to develop a Hadamard–Riesz-type parametrix for the wave propagator in bounded planar domains with smooth, strictly convex boundary. This parametrix then allows us to rederive an oscillatory integral representation for the wave trace appearing in the work by Marvizi and Melrose (1982) and compute its principal symbol explicitly in terms of geometric data associated to the billiard map. This results in new formulas for the wave invariants. The order of the principal symbol, which appears to be inconsistent in the works by Marvizi and Melrose (1982) and Popov (1994), is also corrected. In those papers, the principal symbol was never actually computed and to our knowledge, this paper contains the first explicit formulas for the principal symbol of the wave trace. The wave trace formulas we provide are localized near both simple lengths corresponding to nondegenerate periodic orbits and degenerate lengths associated to one parameter families of periodic orbits tangent to a single rational caustic. Existence of a Hadamard–Riesz-type parametrix with explicit symbol and phase calculations in the interior appears to be new in the literature, with the exception of the author’s previous work [J. Geom. Anal. 31 (2021), 2238–2295] in the special case of elliptical domains. This allows us to circumvent the symbol calculus used by Duistermaat and Guillemin (1975) and Hezari and Zelditch (2012) when computing trace formulas, which are instead derived from integrating our explicit parametrix over the diagonal.
On sub-gaussian concentration of missing mass
Authors: Skorski Maciej
Published: April 2023

Статистические выводы об отсутствующей массе нацелены на оценивание веса элементов, не наблюдавшихся при выборке. Начиная с пионерской работы Гуда и Тьюринга, эта проблема изучалась во многих областях, включая статистическую лингвистику, экологию и машинное обучение. Трудность доказательства субгауссовского поведения отсутствующей массы стала печально известной, и предлагался ряд сложных приемов: логарифмические соболевские неравенства, термодинамические подходы и теоретико-информационные методы переноса массы. Предшествующие работы убеждали, что трудность присуща проблеме и классические инструменты неадекватны. Мы показываем, что это распространенное мнение неверно, и для установления субгауссовской концентрации требуется только классическое неравенство Бернштейна.
Complete and complete integral convergence for arrays of rowwise extended negatively dependent random variables under sublinear expectations
Authors: Xi Mengmei , Li Xiaoqin , Chen Ling , Wang Xuejun J
Published: April 2023

В статье изучается полная и полная интегральная сходимость для массивов построчно обобщенных отрицательно зависимых случайных величин относительно сублинейных ожиданий. Результаты настоящей статьи распространяют результат о полной сходимости, полученный Ху, Ваном и Розальским в 2015 г., и результат о полной моментной сходимости, полученный Ву, Ордоньесом Кабрерой и Володиным в 2014 г., с классического вероятностного пространства на пространство с сублинейным ожиданием.
Задача хеджирования азиатских опционов купли с транзакционными издержками
Authors: Murzintseva Alena Andreevna , Pergamenshchikov Sergey Markovich , Pchelintsev Evgenii Anatol'ievich
Published: April 2023

В статье развиваются асимптотические методы хеджирования азиатских опционов для рынков Блэка-Шоулcа с транзакционными издержками. Сначала строятся классические стратегии репликации, а затем, с использованием подхода Леланда, предлагаются соответствующие модификации для финансовых рынков с пропорциональными транзакционными издержками. Найдены достаточные условия для транзакционных издержек, при которых обеспечивается асимптотическое хеджирование построенных стратегий. Рассмотрена задача ценообразования. Изучены три случая: цена опциона такая же, как для задачи хеджирования без транзакционных издержек, случай возрастающей волатильности и случай, когда цена опциона равна цене стратегии "купить и хранить" для хеджирования европейских опционов купли (call option).
Оптимизация с позиций стоимостного критерия систем обслуживания с перерывами
Authors: Afanasiev Grigory Aleksandrovich
Published: April 2023

Рассмотрена система обслуживания $M|G|1$ с возможностью перерывов (vacations) в работе прибора для основных требований, когда, например, прибор сдается в аренду. Решается задача оптимизации с позиций стоимостного критерия. В качестве контролируемых факторов предлагается вероятность $\alpha$ осуществления перерыва и его продолжительность. При достаточно общих предположениях относительно поведения системы на перерывах установлено, что оптимальное значение вероятности $\alpha$ есть либо нуль, либо единица. Приводятся необходимые и достаточные условия, при которых перерыв следует осуществлять, т.е. $\alpha=1$. При постоянной продолжительности перерывов определены условия, при которых $\alpha=1$, а продолжительность перерыва оптимальна. Рассмотрены два примера. В первом доход от перерыва является линейной функцией его продолжительности, а во втором - квадратичной.
Current and future protection against carbon leakage in the European Emissions Trading System
Authors: Grebe Vera
Published: April 2023

With the Fit for 55 package, the European Commission has proposed a comprehensive reform of the European Emissions Trading System and the introduction of a Carbon Border Adjustment Mechanism (CBAM). A key element of this is the switch of carbon leakage protection from free allocation and electricity price compensation to CO2 pricing of imported goods and greater support for technological innovation in the CBAM sectors (aluminum, cement, electricity, fertilizer, iron, steel, and hydrogen). Whether this new approach will be able to prevail in the face of the immense subsidy approach through the Inflation Reduction Act in the US remains to be seen.
Spatial Water Quality Characteristics of Kallayi River Basin in GIS Platform
Authors: . Nadeeda , P Binisha
Published: April 2023

Kallayi river is a small river situated in Kozhikode district of Kerala. It is well known for its timber business. This river is being polluted by these timber businesses and other human activities, disposal of sewage wastes and many other. This paper deals with the water quality analysis of river Kallayi River basin in post monsoon and premonsoon seasons in the year 2022-2023. GIS and WQI method had been applied to visualize the spatial pattern of the water quality in the study area. A total of 13pre- (March-2023) and post monsoon (December-2022) surface water and groundwater samples were collected and analyzed for pH, turbidity, electrical conductivity, hardness, chloride, DO, BOD, COD, E coli and total coliform. It is very clear from the study that the surface water is highly polluted and it use for nothing, this is because of the human activities like timber business (for which Kallayi river is known), the disposal of sewage, septic wastes, industrial wastes slaughterhouse wastes etc., the ground water near to the downstream of the river is also polluted. Majority of the physio-chemical and biological parameters are higher during pre-monsoon than the post-monsoon. The effect of rain fall in monsoon and successive natural recharge in to the water bodies leads to dilution of the water. In this study some data related to physio chemical parameters of Kallayi River (Kothi) over the year 2012, 2019,2020, 2021,2022 and 2023 were collected and the water quality index is analyzed.
The Rise of the Right
Authors: Winlow Simon , Hall Steve , Treadwell James
Published: April 2023

This book is the first to offer an uncompromising look at the English Defence League (EDL), aiming to alter thinking about working-class politics and the rise of right-wing nationalism in de-industrialised English towns and cities.
Broken Benefits
Authors: Royston Sam
Published: April 2023

In Broken Benefits, Sam Royston argues that social security isn't working, and without a change in direction, it will be even less fair in the future. He provides an introductory guide to social security, correcting misunderstandings and presents practical ideas of how benefits should be reformed.
The Muslim world and the development of science and technology: phase in history
Authors: Kola-Aderoju Sekinat Adejoke
Published: April 2023

Science and technology are inseparable. When scientific knowledge is translated to actions and products that enhance adaptability to one’s immediate environment, technology is then realized. Technology, the world over is the backbone of development. It is tantamount to progress, be it old, new, modern or scientific. it is generally a way of doing things that enhances better livelihood, sustainability and prosperity. Development as a result of technological advancement could be gradual, spontaneous, sporadic or drastic. The intention of this research work is to trace the historical circumstance of the Muslim world in the aspect of science and technology. The paper is also out to consider the concept of the Muslim world as against the Arab nations, the Islamic world, the Middle east and the North-east Africa. Such clarification of concepts will bring to the fore, the idea of progress and its contributions to the global development, taken into cognizance cultural imperialism, Intellectual capital theft assumptions and insinuations. This aspect is of a particular interest to the writer due to the experience of imperialism, imposition and full colonization which were claimed to be factors in the neglect of African indigenous knowledge and technology, such imposition witnessed by sub Saharan Africa was not so prolonged and fully experienced by the Muslim world, hence, there may be a reason to determine, in the course of this research work, the period the Muslim world deviated from the path of technology, considering the current turbulence in the Arab world and finally the global relevance of such early technology. The paper is theoretical, relying on the secondary sources. The paper concludes with recommendations towards further development of the identified intellectual property of the Muslim world.
Formulation, Nutrient Analysis and Sensory Properties of Lemongrass (Cymbopogon Citratus) Incorporated Soup Varieties
Authors:   Student, Department of Nutrition and Dietetics, Sengamala Thayaar Educational Trust Women’s College (Autonomous), Mannargudi, Tamilnadu, India., Thasrin J. Fathima , V. Anitha ,   Assistant Professor, Department of Nutrition and Dietetics, Sengamala Thayaar Educational Trust Women’s College (Autonomous), Mannargudi, Tamilnadu, India.
Published: April 2023

Introduction: Lemongrass (Cymbopogon citratus) is a perennial and promising herb that has more than 500 species with a wide range of growth potentials and special functional qualities which make it more beneficial in many of the foods we consume every day. All parts of lemongrass including leaf, stalk, oil, and flavour are used since they contain the highest levels of nutrients and antioxidants. Objectives: Formulation, analysis of nutrient content and evaluation of sensory qualities of lemon grass incorporated soup varieties. Materials and Method: The raw ingredients were procured, processed, and prepared for three standard varieties of soup namely cabbage soup, radish soup and mushroom soup. Processed lemon grass paste was incorporated at the level of 5%, 10%, 15%, and 20% into three standard soups formulas. All the prepared variations were evaluated for sensory characteristics using a 5-points Likert scale and compared statistically. The most accepted soup variety was chosen for nutrient analysis and finally selected the best incorporation level of lemongrass paste. Results and Discussion: The results stated that lemon grass incorporated radish soup had secured the highest significant overall mean rating score of 16.3 out of 20 when compared to the other two varieties of soups and was also selected as the best soup variation. The nutrient content such as energy, protein, fat, potassium and magnesium of selected lemongrass incorporated radish soups were comparable and 20% level of incorporation achieved maximum nutritional qualities. Conclusion: The findings concluded that the prepared lemon grass incorporated soups were highly acceptable and received good scores in sensory evaluations. The lemongrass-incorporated radish soup was chosen as the best soup and also proved to have a good amount of nutrients. Hence, lemongrass showed high potential as a functional ingredient for soups.
Analysis of the Development of Financial Management Theory to Support Financial Research
Authors:   Jambi University, Budi Utama Ahmad Nur
Published: April 2023

Financial research issues and trends continue to evolve today. Financial management discusses several issues that became a financial attraction in the 1950s related to corporate funding sources. The issue is emphasized on debt funding sources, maturity period extensions, forms of financial assets, increased use of financing sources. The issue continues to grow to this day. Financial management is always concerned with the company’s financial issues that address the financial aspects of the company and also the administrative side during the initial development of the company. Bookkeeping problems are related to the difference between capital and revenue, the administrative side resulting from growth and expansion, and of course financial adjustments are needed to strengthen companies that are experiencing financial difficulties. The problems raised in this study are how the development of financial management theory and the development of financial research until now, as well as how the application of financial management theory to financial research. This research uses qualitative methods. Data collection is carried out by data collection methods in qualitative research, namely observation, visual analysis, and literature study. The development of financial management theories as well as types of financial management research emerged gradually. The development of financial management theory has a history of financial thought can be grouped into several concepts that have their own developments. The foundations of modern financial theory stem from the application of neoclassical economic theory which already uses the assumption that individuals behave rationally. Until the1970s, the application of financial theory was growing up to the current concept, namely behavioral finance.
Providencia Rettgeri Common Causes of UTI
Authors:   Al-Qasim Green University / College of Veterinary Medicine - Iraq Babylon, Abdullhamzah Abdulla Riyadh , Numea Oras Sattar ,   Al-Qasim Green University / College of Veterinary Medicine - Iraq Babylon, Khalil Ahmed Madeeh ,   Al-Qasim Green University / College of Veterinary Medicine - Iraq Babylon, Mohammed Hussein Naeem ,   Wasit University / College of Science – Iraq wasit, Esmaein Muroj Arheem ,   Tikrit University/ College of Science – Iraq Salahaddin, Amir Sarah Hekmat Abdul ,   Science City University College / Department of biology - Iraq Bagdad, Almeer Ahmed Kazem ,   Ministry Of Agriculture – Iraq wasit
Published: April 2023

Wasit city, Iraq provided a total of twenty-four different samples of urine for the researchers to examine. The samples were first cultured onto Ma-Cconkey agar and Blood agar, and placed into brain heart infusion broth. Microscopic inspection, cultural characteristics, biochemical assays, and the Api20 E system were all utilized to independently verify the isolates' identities. Only two out of twenty-four human samples (8.3%) included Providencia species, with P. rettgeri being the most prevalent of those species. Using the disc diffusion technique, tests of antimicrobial susceptibility were carried out against 10 different antibiotics. All of the Providencia isolates had evidence of multidrug resistance (MDR), and the level of absolute resistance to cefoxitin, methicillin, vancomycin, doxycycline, clarithromycin, and trimethoprim/sulfamethoxazole was 100%. They exhibited a high degree of sensitivity to ofloxacin, chloramphenicol, cefixime, and teimethoprim, with a percentage of 100%.
Impact of Farmer-Managed Natural Regeneration on Resilience and Welfare in Mali
Authors: Nkonya Ephraim , Kato Edward , Kabore Carolyn
Published: April 2023

Climate change, poverty, and low environmental education have contributed to increasing vulnerability of poor farmers in Mali. This study was done to determine the impact of low-cost adaptation strategies on resilience and welfare. We analyzed the impact of a World Vision project which promoted climate-smart agricultural (CSA) practices in Mali from 2016-2019. We identified the impact using a two-stage weighted regression (2SWR). Results show that the World Vision Project significantly increased the adoption of Farmer-Managed Natural Regeneration (FMNR) practice and eventually crop yield. These intermediate impacts were translated into a significant reduction in food and nutrition insecurity and an increase in household income. The impacts of the project on child health were especially greater for farmers who participated in the project for a longer time. However, the project did not have a significant impact on the adoption of a combination of CSA practices – which could have enhanced the effectiveness of the FMNR practice. The results suggest the need for future interventions to emphasize the promotion of complementary CSA practices, which significantly increases returns to farmer investments.
 
Received: 30 January 2023 | Revised: 11 April 2023 | Accepted: 20 April 2023
 
Conflicts of Interest
The authors declare that they have no conflicts of interest to this work.
 
Data Availability Statement
Data sharing not applicable – no new data generated.
Comparing BERT Against Traditional Machine Learning Models in Text Classification
Authors: Garrido-Merchan Eduardo C. , Gozalo-Brizuela Roberto , Gonzalez-Carvajal Santiago
Published: April 2023

The BERT model has arisen as a popular state-of-the-art model in recent years. It is able to cope with NLP tasks such as supervised text classification without human supervision. Its flexibility to cope with any corpus delivering great results has make this approach very popular in academia and industry. Although, other approaches have been used before successfully. We first present BERT and a review on classical NLP approaches. Then, we empirically test with a suite of different scenarios the behaviour of BERT against traditional TF-IDF vocabulary fed to machine learning models. The purpose of this work is adding empirical evidence to support the use of BERT as a default on NLP tasks. Experiments show the superiority of BERT and its independence of features of the NLP problem such as the language of the text adding empirical evidence to use BERT as a default technique in NLP problems.
 
Received: 10 March 2023 | Revised: 4 April 2023 | Accepted: 20 April 2023
 
Conflicts of Interest
The authors declare that they have no conflicts of interest to this work.
Examining the Structure of QR Codes to Improve Encryption and Decryption
Authors: Vedant Borkar  , Yash Khadole  , Chirag Soni  , Praful Wankhede
Published: April 2023

Black and white barcode have become utilised in the past decade to encode more data per square unit. The barcode is a series of bars and spaces organised in a certain pattern. It exemplifies the appropriate approach to provide knowledge. Data is retained gradually in 2D matrices. Such codes are known as two-dimensional shapes codes. Many applications are briefly explored, as well as the structure, symbology, and features of barcodes. Throughout 2007 and 2010, this study paper discussed ways to provide QR codes using word processing software. The major goal of the study is to design and grasp QR code technology in the context of today's society. Component, formatting, style, styling, insert are all terms.
Implementation of Newsly Aggregator using Django Framework
Authors: Alok Chauhan  , Akansha Meshram  , Pratiksha Meshram  , Aakanksha Bhope  , Rupali Gaurkar  , Ashitosh Gajbhiye
Published: April 2023

The newsly web is a platform where we are filtering, aggregating news and providing the information or news for user friendly experience at one place. Newsly aggregator is a very simple and user-friendly application. In a news aggregator, user can select the websites user want to follow. Visiting many separate websites frequently to find out if the content on the site has been updated can take a long time. Newsly Aggregation technology helps to consolidate many websites into one page that can show only the new or updated information from many sites. Newsly Aggregators reduce the time and effort. News and providing the content for user friendly experience at one place In Newsly we have used HTML, CSS, JavaScript and bootstrap for the front End. We use crispy forms python, Django for the back-end support. This paper will explore the advancements in AI and NLP that are expected to shape the future, as well as the potential implications of human interaction
Water Resource Management
Authors: D. Arun Shunmugam  , M. Richard Kumar  , S. Gokul  , P. Jeya Ramanan
Published: April 2023

Water makes up about 70% of the earth’s floor and is one of the most vital sources essential to maintaining life. Speedy urbanization and industrialization have led to a deterioration of water best at an alarming fee, ensuing in harrowing illnesses. Water high- quality has been conventionally estimated through expensive and time-ingesting lab and statistical analyses, which render the cutting-edge belief of real-time tracking moot. The alarming results of bad water nice necessitate an alternative approach that is quicker and inexpensive. With this motivation, this study explores a sequence of supervised device mastering algorithms to estimate the water high-quality. The proposed methodology achieves affordable accuracy the use of a minimum number of parameters to validate the possibility of its use in real time water first-class detection systems. It demonstrates the overall maintenance and management of the water quality and quantity inside a plant using modern technologies. It based on the systematic working process to reduce the man power and cost maintenance for the industrialization development.
Zertifizierungsgerechter Entwurf betriebsmitteladäquater Automatisierungssysteme mit Sicherheitsverantwortung
Authors: Koß Daniel
Published: April 2023

Programmierbare elektronische Systeme für sicherheitsgerichtete Anwendungen werden nach Prüfung durch Menschen sicherheitstechnisch abgenommen. Für den praktischen Einsatz können nur solche Systeme zertifiziert werden, die Menschen zuvor als weitestgehend frei von sicherheitskritischen Entwurfsfehlern befunden haben. Komplexität kommt hierbei eine besondere Bedeutung zu, da von ihr die Verstehbarkeit von Systementwürfen abhängt. Betriebsmitteladäquatheit ist ein essentielles Element zur Komplexitätsminimierung und hat darüber hinaus weitere, ausfalltolerierende Auswirkungen. Ziel dieser Arbeit ist daher, die im Entwurfslebenszyklus sicherheitsgerichteter programmierbarer elektronischer Systeme eingesetzten Methoden dahingehend zu verbessern, dass Komplexität durch konsequente Anwendung von Betriebsmitteladäquatheit reduziert wird. Dies führt zu verbesserter Prüfbarkeit und damit zu sichereren Systemen. Inhaltsverzeichnis 1 Einleitung 1 1.1 Ziele der Arbeit . . . . . . . . . . . . . . . . . . 1 1.2 Beispiele für sicherheitsrelevante Ausfälle . . . . . . 2 1.2.1 Mars Pathfinder . . . . . . . . . . . . . . . . . . . 2 1.2.2 Transienter Fehlereinfluss schneller Neutronen . . ....