bluuebunny/crossref_metadata_2025 huggingface dataset:
Examining Workplace Incivility as an Antecedent of Knowledge Hiding Behavior
Authors: Kumar Shalendra S. , Kang Shinhyung , Kishore Rohit
Published: March 2021

This study aims to examine the influence of workplace incivility on knowledge-hiding behavior. The study also examines the moderating role of an individual’s need for achievement between the two constructs. The data was collected from 331 individuals through convenience sampling from the public sector in the unstable economy of Fiji. The proposed model was tested through structural equation modeling. While the average variance extracted and composite reliability exceeded the recommended threshold of 0.5 and 0.7, the Cronbach's alpha ranged from 0.88 to 0.91. Thus, the measurement constructs were found to be suitable and sound for the research. The findings of the study show a significant positive relationship between workplace incivility and knowledge-hiding behavior accepted. Furthermore, the individual’s need for achievement significantly moderates the relationship between workplace incivility and knowledge-hiding behavior. While the extant literature implicitly regards workplace incivility as a negative phenomenon with a great tendency for knowledge-hiding behavior, this research shows that the deleterious effect of workplace incivility on knowledge-hiding can be moderated through an individual’s need for achievement. The findings further suggest that individuals with a need for achievement have a greater propensity to change the negative phenomenon into a positive challenge. This will be our major contribution to the extant literature. It is also proposed that the organization invest more in emotional management training, leadership training, empowering workers, and creating awareness of the importance of civil behavior at work. Finally, the implications, limitations, and suggestions for future research are discussed.
Experimental estimation of the efficiency of removing residual amounts of antibiotics and steroid hormones from water with home water purification systems
Authors: Ремизова Ю.А. , Голованова А.П. , Рудакова Д.А. , Митилинеос А.Г.
Published: March 2021

Для удаления остаточных количеств фармацевтических соединений, присутствующих в питьевой воде, на всех этапах водоподготовки могут применяться разнообразные способы очистки, основанные на различных физико-химических принципах. В работе приведены результаты экспериментального исследования эффективности удаления с помощью бытовой стационарной системы водоочистки остаточных количеств фармацевтических препаратов – антибиотика левомицетина (хлорамфеникола) и стероидного гормона эстрона – из модельного раствора, приготовленного на основе водопроводной воды с добавлением лекарственных препаратов. Показано, что бытовая система водоочистки обладает способностью существенно снижать остаточные концентрации фармацевтических препаратов левомицетина и эстрона на всем протяжении заявленного производителем ресурса. В секторе бытовой водоочистки установки адсорбционного типа по-прежнему остаются наиболее востребованным типом водоочистных систем, обеспечивающих высокую эффективность удаления различных загрязнителей при минимальных капитальных затратах.

To remove residual amounts of pharmaceutical compounds present in drinking water, a variety of purification methods based on various physicochemical principles can be used at all stages of water treatment. The paper presents the results of an experimental study of the efficiency of removing residual concentrations of pharmaceuticals – laevomycetin antibiotic (chloramphenicol) and estrone steroid hormone – from a model solution prepared on the basis of tap water with the addition of drugs, using a home fixed water purification system. It is shown that the home water purification system provides for the significant reduction of residual concentrations of chloramphenicol and estrone throughout the service life declared by the manufacturer. In the household water purification sector, adsorption-type units are still the most in-demand type of water purification systems that provide for the high efficiency in removing various pollutants with minimal capital costs.
Improving the method for monitoring the piezometric level of underground water in production wells of the Kamchatka Territory
Authors: Опрышко Б.А. , Швецов В.А. , Белавина О.А.
Published: March 2021

Приведен опыт в области контроля гидродинамического режима подземных напорных вод при их эксплуатации. Для измерения и корректировки результатов измерений пьезометрического уровня подземных вод в самоизливающихся скважинах использовали автономные автоматизированные измерительные устройства. Экспериментальные исследования проводили на наблюдательной скважине № 1 Мильковского месторождения подземных питьевых вод (Амшарикский участок). Результаты исследований показали, что максимальный уровень подземных вод соответствует периоду таяния снежного покрова (май–июнь). Минимальный уровень подземных вод наблюдали в апреле. Отмечено, что годовой график изменения уровня воды в скважине № 1 не соответствует полностью ни одному из типовых графиков, что свидетельствует о необходимости организации автоматизированного контроля гидродинамического режима данного месторождения подземных вод с целью защиты его от истощения и загрязнения.

The experience in monitoring the hydrodynamic regime of underground pressure water in the process of exploitation is presented. To measure and correct the results of measurements of the piezometric level of underground water in blowing wells, self-contained automated measuring devices were used. The experimental studies were carried out at observation well No. 1 of the Mil’kovskoe deposit of underground drinking water (Amsharikski site). The research results showed that the maximum underground water level corresponded to the period of snow cover melting (May – June). The minimum underground water level was observed in April. It is noted that the annual schedule of the water level changes in well No. 1 does not fully comply with any of the standard schedules suggesting the need to establish automated control of the hydrodynamic regime of this underground water deposit in order to protect it from depletion and pollution.
Reconstrução de curvas paramétricas por meio de uma abordagem probabilística
Authors: Silva Marcones de Oliveira , Lima Thiago Amaral Melo
Published: March 2021

Este trabalho trata da reconstrução de curvas paramétricas utilizando funções de densidade de probabilidade para gerar uma amostragem de pontos no domínio da curva e aproximado-a em um intervalo específico. Existem várias abordagens para amostrar curvas paramétricas, que permitem que a mesma esteja de acordo com a curvatura ou comprimento de arco. Em geral, estas técnicas estão baseadas em heurísticas, e não conseguem dar soluções ótimas. Neste artigo, pretendemos usar uma abordagem probabilística, de modo que a amostragem de pontos resultante esteja de acordo com alguma função de densidade definida no domínio da curva, colocando mais pontos onde esta densidade é maior. Por ser mais geral, esta abordagem inclui os casos mencionados acima como casos particulares. Em geral, aproximar curvas planas com base na Distribuição Uniforme se revelou mais eficiente do que tomando como referência a Distribuição Exponencial. O valor de lambda na Distribuição Exponencial interfere na aproximação de algumas curvas, sendo necessário encontrar um valor de lambda adequado para chegar a uma boa aproximação da curva. Aproximar a curva com base na sua curvatura é um método usado quando se deseja gerar mais amostras onde a curvatura é maior. Porém, esse método só pode ser usado em casos especiais uma vez que a integral da função curvatura, na maioria das vezes, é muito difícil de ser calculada.
Visualization of water concentration distribution in human skin by ultra-multiplex coherent anti-Stokes Raman scattering (CARS) microscopy
Authors: Kaneta Daiki , Kimura Masahiro , Leproux Philippe , Couderc Vincent , Goto Makiko , Egawa Mariko , Kano Hideaki
Published: March 2021

Ultra-multiplex coherent anti-Stokes Raman scattering (CARS) spectroscopic imaging was used to visualize the distribution of water concentration in human skin ex vivo. The CARS signal of the OH stretching vibrational mode of water was found to coexist with the signal of intercellular lipids such as ceramides, which were visualized by a sharp vibrational band at 2882 cm−1. Depth-resolved CARS spectroscopic imaging of a skin sample revealed that ceramides were localized in the stratum corneum. These findings demonstrate the powerful potential of CARS spectroscopic imaging for probing pathological changes caused by anomalous water concentration distribution in human skin.
A STUDY OF RELATIONSHIP OF ANTHROPOMETRIC INDICES WITH BLOOD
PRESSURE AND BLOOD GLUCOSE LEVEL IN ADULT POPULATION AT PMCH,
PATNA
Authors: Kumari Nutan , Rani Vibha , Singh [Prof.] Rajiva Kumar , Jana Debarshi
Published: March 2021

Diabetes is the 5 or 6 leading cause of death worldwide (as per International Diabetes Federation 2009). The crude prevalence of diabetes (type 1
and 2) in adults 20-79 years of age was estimated to be 6.6% (285 million) in 216 IDF member countries in 2010 (as per International Diabetes
Federation 2009). By 2030, this gure is expected to rise to 7.8% (438 million), with the largest increase in regions where economies are
developing further. They further emphasized that if the levels of obesity continue to increase, the prevalence of diabetes may be even greater than
that reported in the IDF 2009 report. Hypertension is considered as the primary risk factor for stroke, ischaemic heart disease (Nakamura et al 2008)
and cardiovascular disease (CVD) mortality (Martiniuk et al 2007; He et al 2009). Recently, it was estimated that 7.6 million premature deaths per
year may be attributed to high blood pressure (Lawes et al 2008), that is 13.5% of the total global deaths. About 26.4% or 972 million of the world
adult population had hypertension in 2000 of which 333 million were in economically developed countries and 639 million in economically
developing countries (Kaarney et al 2005), gures predicted to increase by 60% to 1.56 billion in 2025.
ROLE OF VESTIBULAR EVOKED MYOGENIC POTENTIALS (VEMP) IN
PREDICTING THE OUTCOME OF STAPEDOTOMY- A PROSPECTIVE
OBSERVATIONAL STUDY
Authors: Palanisamy Thirunavukarasu , Jayagandhi Sathishkumar , Lakshmanan Somu , Prabakar Ajaykumar , Arun Arthi , Manimaran Vinoth
Published: March 2021

Vestibular evoked myogenic potentials (VEMP) is an objective and non-invasive measure of saccule function that primarily respond to linear
acceleration in any direction. Stapedotomy is a procedure done for otosclerosis to improve hearing. The aim of this study was to correlate the
VEMPresults with pure tone audiogram pre- and post- stapedotomy in otosclerotic patients. Aprospective observational study was conducted from
2017-2020 in a tertiary care hospital of south India. Patients who underwent stapedotomy for otosclerosis and satised the study criteria were
included. Atotal of 22 patients were included in the study. All patients underwent pure tone audiogram (PTA) and VEMP preoperatively and postoperatively. The results were compared and analysed. The mean pre-operative and post-operative ABG were 26.32±9.36 dB and 18.10 ±8.06 dB
respectively. (P=0.001). There was no signicant change in VEMP positivity rates, latency and amplitude. The results showed that there was no
correlation between the PTAvalues and VEMPpositivity rate in otosclerotic patients. The VEMPpositivity rate was also not affected signicantly
by stapedotomy. Based on above ndings we conclude that stapedotomy is a safe and effective procedure with no signicant inner ear trauma.
NORMALAND ABNORMAL LIQUOR VOLUME AND ITS CORRELATION WITH
PERINATAL OUTCOME
Authors: Nisha Kumari , Jha Renu , Jha Kumudini , Jana Debarshi
Published: March 2021

Aim:To assess and compare the perinatal outcome among mothers with normal and abnormal amniotic uid volume.
Method: A prospective comparative study was conducted for a period of one year from January 2020 to December 2020. Group I consist of 50
patients with normal amniotic uid and group II consists of 50 patients with either oligohydramnios or polyhydramnios. Amniotic uid index (AFI)
was calculated using Phalen's four quadrant technique using ultrasound. The perinatal outcome was judged by assessing the fetal distress predicted
by abnormal fetal heart rate (FHR) or meconium stained liquor, one minute and 5 minute Apgar score, frequency of admission to neonatal intensive
care unit (NICU), baby weight of less than 10th percentile for gestation age and perinatal mortality.
Results: Induction of labour, caesarean section and meconium stained liquor was found to be most common among the patients in group II
(abnormal AFI) in comparison with normal AFI subjects and similarly the perinatal outcome measures like low birth weight, increased frequency
of admission to NICU due to respiratory distress and a low APGAR score was more commonly found in abnormal AFI group and the difference was
found to be statistically signicant.
Conclusion: AFI measurement in antepartum or intrapartum period can help to identify women who need increased antepartum surveillance for
pregnancy complications and such women should be managed in a special unit to combat the complications effectively.
DYSLIPIDEMIA IN NON ALCOHOLIC FATTY LIVER DISEASE
Authors: Kumari Ruby , Kumar Prof. Santosh , Jana Debarshi
Published: March 2021

Background: NAFLD is a major alarming public health problem in current scenario. Still there is lack of wide research data in context of NAFLD,
in our institute and state (Jharkhand) so we felt the need to do this research to assess dyslipidemia in cases of NAFLD. 100 Material and methods:
patients (18-70 yrs) age Group, were included in the study. 50 diagnosed cases of Fatty Liver disease (FLD) by USG were enrolled in study.
Subjects were divided in two equal groups, NAFLD and controls. Lipid prole was done in both groups. Data obtained during research was Result:
statistically analyzed by using SPSS version 20. Student t test for independent samples was used to determine statistical signicance, p-value <0.05
was considered statistically signicant. serum Triglyceride, serum LDL-C and VLDL-C was signicantly raised and HDL-C signicantly
decreased in NAFLD group compared to control. Dyslipidemia was obtained in NA Conclusion: FLD group.
MATERNAL RISK FACTORS ASSOCIATED WITH PRETERM BIRTH IN A
TERTIARY RURAL CARE CENTER
Authors: Yadav Rohan , Kumar P. Sunil , B. Mahendrappa K. , Kumar G.M. , N Channabasavanna
Published: March 2021

Introduction. In India, according to 2010 data 3.5 million babies are born premature out of 27 million babies born every year which constitutes to
23.6% of world total preterm births. Preterm morbidity is not only limited to neonatal period but also extends to later life resulting in continuous
physical, psychological and economic stress to the individual and family. Since few studies have been done on preterm babies in a rural setup to
assess the common maternal risk factors responsible for preterm birth this observational study of maternal risk factors associated with preterm birth
has been taken up.
Material and methods. st st This is a prospective observational study done from 1 August 2019 - 31 July 2020 in Adichunchanagiri Institute of
Medical sciences, Mandya. Study sample comprised of 100 preterm babies born in the study period. Data was collected on a preformed Performa, it
was compiled and entered in MS excel sheet.
Results. In this study majority of women who delivered prematurely were primigravida (53.8%). Majority of women in this study belonged to age
group 19-22 years (43.9%). More babies were delivered via LSCS (52%) when compared to vaginal route. Majority of women belonged to class III
socio economic status (54.9%). Common maternal risk factors were PROM (30.8%), preeclampsia (20.9%), APH (13.2%) and Anemia
(6.6%).19.8% of women had previous BOH of which most common was abortion (14.2%). Common fetal risk factors were Breech (11%), Multiple
gestation (9.9%).
Conclusion. Identication of maternal risk factors and early intervention can reduce the number of preterm deliveries and their associated
morbidity and mortality.
POLA DIDIK ORANGTUA DALAM PEMBINAAN AKHLAK ANAK (Studi Kasus pada Orangtua Single Parent di Kecamatan Haurgeulis)
Authors: Saepulloh Saepulloh
Published: March 2021

Tulisan ini mengkaji pola didik orang tua dalam pembinaan akhlak. Metode yang digunakan dalam penelitian ini adalah kualitatif dan objek penelitian adalah sebagian keluarga di salah satu kabupaten yang ada di Jawa Barat, dimana keluarga yang memenuhi keriteria yaitu keluarga yang “utuh”, dan memiliki anak usia sekolah yang berakhlakul karimah dan disiplin, keluarga single parent dan keluarga “tidak utuh” serta memiliki anak sekolah yang kurang berakhlak baik dan tidak disiplin diri. Data yang terkumpul dianalisis secara reduktif fenomenologis dan editik selama pengumpulan data berlangsung. Kegiatan meliputi mereduksi data, menyajikan data, menarik kesimpulan, dan melaksanakan verifikasi. Dalam mereduksi data pada penelitian ini, penulis melakukan upaya untuk “kembali” kepada yang telah ada terdahulu. Hasil penelitian menunjukan bahwa sebagian besar orang tua cenderung mendidik anak-anak mereka dengan pola otoriter, namun demikian sebagian dari mereka juga menggunakan pola didik demokratis dan bebas. Demikian juga sebagian besar orang tua melakukan pembinaan akhlak kepad anak-anaknya, namun demikian, sebagian dari mereka juga kurang dalam membina akhlak anak-anaknya. Dari hasil analisis penelitian ini dapat disingkapkan sruktur dasar yang membuat anak-anak memiliki dan mengembangkan akhlak yang mulia merupakan kesatuan utuh dari masing-masing pembinaan orang tua. Hubungan pola didik orang tua dalam pembinaan akhlak anak dengan tingkatan apresiasi anak berdasarkan kata hati, nalar dan naluri terjadi karena pasang surutnya kewibawaan dan kepercayaan terhadap orang tua dapat menggetarkan dawai kata hatinya sehingga kewibawaan dan kepercayaan orang tua memiliki medan pesona mental roundrtrip secara psikologis dan emosional, serta nilai-nilai agama harus bermakna secara ekumeni transendentaldalam kerangka hubungan dengan Allah dan sesama manusia.
Hubungan Kesesuaian Peresepan Obat dan Kendali Biaya Berdasarkan Formularium Nasional Pada Pasien BPJS Rawat Jalan di RSUD Ungaran Kabupaten Semarang
Authors: Indrasari Ferika
Published: March 2021

Formularium Nasional merupakan daftar obat terpilih yang dibutuhkan dan tersedia di fasilitas pelayanan kesehatan sebagai acuan dalam pelaksanaan Jaminan Kesehatan Nasional. Tujuan utama pengaturan obat dalam Formularium Nasional untuk meningkatkan derajad kesehatan melalui peningkatan dan efektifitas pengobatan sehingga tercapai penggunan obat rasional (Depkes RI, 2015). Penelitian ini bertujuan untuk mengetahui hubungan antara tingkat kesesuaian peresepan obat dengan Formularium Nasional pasien BPJS Rawat Jalan terhadap kendali biaya obat di RSUD Ungaran.Penelitian ini merupakan penelitian secara deskriptif non-eksperimental dengan metode pengambilan data retrospektif dan data yang dikumpulkan berupa data kuantitatif. Teknik pengambilan data menggunakan random sampling. Data peresepan obat pasien BPJS Rawat Jalan diperoleh dari resep periode Oktober – Desember 2018. Data kemudian diolah secara deskriptif.Hasil penelitian menunjukkan bahwa Tingkat kesesuaian peresepan obat berdasarkan Formularium Nasional pada pasien BPJS Rawat Jalan di RSUD Ungaran 77,96% yang artinya belum sesuai dengan indikator berdasarkan Formularium Nasional bahwa kesesuaian peresepan berdasarkan formularium 100%. Besarnya selisih biaya obat diluar Formularium Nasional rata-rata 41,38% setiap bulannya. Thubungan yang bermakna antara kesesuaian peresepan obat berdasarkan Formularium Nasional dan selisih biaya obat dengan nilai Sig.(2-tailed) 0,000 (p < 0,050). Oleh karena itu perlu adanya upaya sosialisasi yang berkesinambungan kepada prescriber bahwa Formularium Nasional sebagai pedoman pengobatan untuk pasien BPJS untuk meningkatkan mutu pelayanan dan pengendalian biaya obat. Keywords : Peresepan Obat, Kendali Biaya, Formularium Nasional
POTENSI ANTIKANKER EKSTRAK SPONS LAUT NATUNA DENGAN METODE BRINE SHRIMP LETHALITY TEST (BSLT)
Authors: Mayefis Delladari
Published: March 2021

Indonesia, khususnya di Kepulauan Riau memiliki kekayaan biota laut yang melimpah. Salah satunya adalah spons yang mengandung berbagai macam metabolit sekunder yang memiliki sifat toksik untuk membunuh sel kanker. Potensi sitotoksik yang dimiliki spons dapat digunakan sebagai sumber obat antikanker baru, mengingat kanker merupakan penyakit dengan tingkat kematian tertinggi didunia. Penelitian ini bertujuan untuk mengetahui potensi senyawa bioaktif antikanker pada ekstrak spons laut di Perairan Natuna, Kepulauan Riau. Metoda yang digunakan untuk skrining awal potensi antikanker adalah metoda BSLT. Hasil yang diperoleh menunjukan bahwa toksisitas ekstrak kasar metanol spons laut natuna mempunyai LC50 sebesar 51,64 ppm dan tergolong sangat toksik . Hal ini mempunyai kontribusi besar terhadap pengembangan sumber daya laut yang spesifik asal Kepulauan Riau, dan dapat dikembangkan lebih lanjut sebagai kandidat obat antikanker unggulan.
Pengaruh Ekstrak Etanol Kurma Ajwa (Phoenix dactylifera L.) Terhadap Efek Afrodisiak Pada Mencit (Mus muscullus L) Putih Jantan Obesitas
Authors: DILLASAMOLA DWISARI
Published: March 2021

ABSTRAK Penurunan afrodisiak merupakan penyakit disfungsi seksual. Salah satunya disebabkan karena obesitas yang memicu rendahnya kadar hormon testosteron total di bagian perifer jaringan adiposa penderita obesitas. Kurma ajwa (Phoenix dactylifera L.) memiliki aktivitas afrodisiak yang mampu meningkatkan gairah seks. Penelitian ini menggunakan ekstrak etanol kurma ajwa (Phoenix dactylifera L.) dengan dosis 158 mg/kgBB, 317 mg/kgBB dan 476 mg/kgBB. Untuk melihat efektivitas afrodisiak kurma ajwa (Phoenix dactylifera L.) pada mencit (Mus muscullus L.) putih jantan menggunakan parameter ICC (Introducing, climbing, coitus) dan diperlakukan selama 14 hari. Berdasarkan hasil analisis data yang dilakukan menggunakan Uji One Way Anova didapatkan nilai Sig. kecil dari Sig. α (0.05). Dan ekstrak etanol kurma ajwa (Phoenix dactylifera L.) memiliki efektifitas afrodisiak pada dosis 158 mg/kgBB. Kata kunci : Afrodisiak, daun katuk (Sauropus androgynus (L.), obesitas  ABSTRACT Low sexual desire or low libido is one of the most common male sexual dysfunction. One of them is caused by obesity which triggers low levels of the total testosterone hormone in the peripheral part of the adipose tissue of obese people. Kurma Ajwa (Phoenix dactylifera L.) have aphrodisiac activity which can increase sex drive. This study used the ethanol extract of kurma ajwa (Phoenix dactylifera L.) with a dose of 158 mg / kg, 317 mg / kg and 476 mg / kg of weight. To see the effectiveness of the aphrodisiac of Kurma Ajwa (Phoenix dactylifera L.) in male white mice (Mus muscullus L.) using ICC (Introducing, climbing, coitus) parameters and treated for 14 days. Based on the results of data analysis carried out using the One Way Anova test, the Sig. small of Sig. α (0.05). And the ethanol extract of kurma ajwa (Phoenix dactylifera L.)Keywords : Aphrodisiac, katuk leaves (Sauropus androgynus (L.), obesity
KARAKTERISTIK SENSORIS DAN KANDUNGAN LOGAM BERAT MINUMAN FUNGSIONAL OKRA-JAHE DENGAN BERBAGAI JENIS PEMANIS
Authors: Amelia Julfi
Published: March 2021

Okra merupakan sayuran yang dapat dikonsumsi dalam keadaan segar maupun diolah. Okra dapat dimanfaatkan menjadi minuman kesehatan karena kaya akan zat gizi dan fitokimia yang bermanfaat bagi kesehatan. Minuman okra memiliki nilai sensori yang kurang baik, sehingga perlu adanya bahan tambahan untuk memperbaiki hal tersebut. Bahan tambahan yang dapat digunakan adalah jahe dan pemanis untuk meningkatkan nilai sensori aroma dan rasa. Jahe merupakan tanaman herbal yang memiliki kandungan yang baik bagi kesehatan serta memiliki flavor yang khas. Pemanis yang digunakan dalam penelitian ini adalah daun stevia, madu, sorbitol dan sukrosa. Penelitian ini bertujuan untuk mengkarakterisasi sifat sensori dan kandungan logam berat minuman fungsional okra-jahe dengan penambahan berbagai jenis pemanis. Sifat sensori menggunakan uji hedonik dengan parameter warna, rasa, aroma, dan kekentalan, sedangkan pengujian kimia terhadap kadar logam berat meliputi Pb, Cd, As, Hg, Sn. Perbandingan antara okra:jahe:pemanis adalah 75%:3%:22%. Berdasarkan uji hedonik, untuk parameter warna dan kekentalan minuman okra dengan pemanis sorbitol mendapatkan skor yang tertinggi. Sedangkan pada parameter rasa dan aroma, minuman okra dengan pemanis sukrosa mendapatkan skor yang tertinggi. Hasil analisis kadar logam berat Pb, Cd, As, Hg, dan Sn menunjukkan hasil negatif di semua sampel.  ABSTRACT: Lady’s finger is a vegetable that can be consumed fresh or processed. Lady’s finger can be used as a functional drink because it is rich in nutrients and phytochemicals that are beneficial to health. Unfortunately this drink has poor sensory performance, so it needs additional ingredients to improve this sensory properties. Additional ingredients include ginger and sweetener to increase the sensory acceptability of aroma and taste. Ginger is an herbal plant that has a bioactive content that is good for health and has a distinctive flavor. The sweeteners used in this study were stevia leaves, honey, sorbitol and sucrose. This study aimed to characterize the sensory properties and heavy metals contet of lady’s finger-ginger functional drinks with the addition of various types of sweeteners. Sensory properties were observed using hedonic tests with parameters of color, taste, aroma, and viscosity, while the chemical analysis was focused on the levels of heavy metals including Pb, Cd, As, Hg, Sn. The ratio of lady’s finger: ginger : sweetener in the formulation were 75: 3: 22. Based on the hedonic test, for color and viscosity of lady’s finger drinks with sorbitol sweetener got the highest score. While on the taste and aroma parameters, lady’s finger drinks with sucrose sweetener get the highest score. The results of heavy metals on Pb, Cd, As, Hg, and Sn showed undetected in all samples. Keywords: Drink, ginger, lady’s finger, sweeteners
IDENTIFIKASI DAN KARAKTERISASI BAKTERI ASAM LAKTAT PADA ACAR KETIMUN (Cucumis sativus L.) SEBAGAI AGENSI PROBIOTIK
Authors: Surbakti Febry
Published: March 2021

Di Indonesia terkenal dengan berbagai macam makanan tradisional fermentasi. Jenis makanan tradisional yang banyak dijumpai yang diproses dengan menggunakan proses fermentasi adalah tape, asinan, acar dan lainnya yang mengandung banyak bakteri asam laktat (BAL). Bakteri asam laktat ini merupakan kekayaan alam mikroba yang masih harus dieksplorasi dibidang kesehatannya. Penelitian ini bertujuan untuk mengetahui jenis-jenis dan karakteristik bakteri asam laktat yang terdapat pada acar ketimun. Penelitian ini menggunakan metode deskriptif. Teknik pengambilan sampel langsung dilakukan secara aseptis. Bahan yang digunakan adalah bakteri asam laktat yang diambil dari cairan acar ketimun dengan variasi isi ketimun, ketimun nenas, ketimun nenas dan cabai dan ditumbuhkan pada media MRS Broth (de Man Rogosa Sharpe). Berdasarkan hasil penelitian identifikasi dan karakterisasi bakteri asam laktat pada acar ketimun dengan menggunakan uji morfologi, pewarnaan gram dan uji biokimia maka diperoleh 2 jenis bakteri asam laktat pada acar ketimun. Adapun bakteri asam laktat yang ditemukan antara lain adalah Lactobacillus plantarum dan Lactobacillus reuteri. Karakterisitik secara umum adalah basil, gram positif, katalase negatif, tidak motil, suhu optimum 250°C- 300°C dan memiliki tipe fermentasi heterofermentatif dan homofermentatif.  ABSTRACT: In Indonesia it is famous for various kinds of traditional fermented foods. Traditional food types that are often found that are processed using fermentation are tape, pickled, pickled and others that contain a lot of lactic acid bacteria (LAB). This lactic acid bacteria is a natural wealth of microbes that must still be explored in the field of health. This study aims to determine the types and characteristics of lactic acid bacteria found in pickles to Cucumber. This research uses a descriptive method. The direct sampling technique is carried out aseptically. The material used is lactic acid bacteria taken from pickled liquid to Cucumber with various contents to Cucumber, to Pineapple Cucumber, to Cucumber pineapple and chili and grown on MRS Broth media (de Man Rogosa Sharpe). Based on the results of the study of identification and characterization of lactic acid bacteria on pickles to Cucumber using morphological tests, gram staining and biochemical tests, 2 types of lactic acid bacteria were obtained on pickles to Cucumber. The lactic acid bacteria found include Lactobacillus plantarum and Lactobacillus reuteri. General characteristics are basil, gram positive, negative catalase, not motile, optimum temperature 250C-300C and have heterofermentative and homofermentative fermentation types. Keywords: Lactic acid bacteria, Probiotik, Pickled cucumber
KARAKTERISTIK SENSORIS DAN KANDUNGAN SERAT BISKUIT DARI JANTUNG PISANG (Musa paradisiaca) SEBAGAI MAKANAN SELINGAN ANAK OBESITAS
Authors: Khoirunisa Hersa
Published: March 2021

Penelitian ini bertujuan untuk menghasilkan makanan fungsional berupa produk biskuit tinggi serat yang dapat dijadikan makanan selingan anak obesitas. Rancangan percobaan yang digunakan dalam penelitian ini adalah rancangan acak lengkap dengan factor berupa jenis formula. Pemilihan biskuit terbaik dilakukan dengan menggunakan metode pembobotan antara nilai gizi dan hasil uji hedonik. Biskuit F1 dengan subtitusi 35% dan F2 dengan subtitusi 45% tidak memiliki perbedaan yang nyata dari hasil analisis uji hedonik menggunakan ANOVA, sehingga F2 merupakan formula terpilih dengan kandungan serat yang lebih tinggi dari F1 setara dengan 13% dari Angka Kecukupan Gizi (AKG) serat. Satu takaran saji (50g) biskuit jantung pisang mengandung energi 220 Kal, 3.55g protein, 8.9g lemak, 31.64g karbohidrat, dan 3.99g total serat pangan.  ABSTRACT: The aim of this study was to produce functional foods in the form of high-fiber biscuit that could be used as a snack for obese children. The experimental design used in this study was a completely randomized design with the formulas as the treatment factor. The selection of the best biscuits was done by weighting method between nutritional value and the result of hedonic test. F1 biscuits with 35 % substitution of banana inflorescence flour and F2 with 45% substitution did not have significant difference by ANOVA of the hedonic test result, so F2 with higher fiber than F1 was chosen as the preferred formula, which could contribute 13% of fiber based on Recommended Dietary Allowance (RDA). One serving (50g) of banana inflorescence biscuits contains 220 Kal, 3.55g protein, 8.9g fat, 31.64g carbohydrate, and 3.99g of total dietary fiber. Keywords: Banana inflorescence, biscuit, fiber, obesity
MUTU SAUERKRAUT KUBIS DAN WORTEL GRADE RENDAH DENGAN KONSENTRASI GARAM YANG BERBEDA
Authors: Nakdiyani Ranny
Published: March 2021

Garam adalah bahan yang mempengaruhi kualitas fermentasi sauerkraut. Garam digunakan untuk menghilangkan air dari sayuran dan digunakan oleh bakteri asam laktat untuk tumbuh. Kubis dan wortel kelas rendah dapat diolah dengan sauerkraut untuk meningkatkan nilai ekonomi. Inti dari penelitian ini adalah untuk mendapatkan konsentrasi garam yang dapat memanfaatkan kol dan wortel sauerkraut terbaik. Desain penelitian yang digunakan adalah Rancangan Acak Lengkap (RAL) dengan satu faktor yang terdiri dari 4 taraf (A1: 2,5%; A2: 5%; A3: 7,5%; A4: 10%) dan 4 pengulangan. Kualitas Sauerkraut dianalisis dengan uji organoleptik (mutu hedonik dan hedonik), uji fisik (susut bobot), uji kimia (pH, kadar air dan total padatan terlarut), vitamin C dan konsentrasi asam laktat. Data diolah secara statistik menggunakan aplikasi SPSS dengan analisis satu arah (ANOVA). Tindak lanjut Duncan dilakukan untuk mengetahui perbedaan antara perlakuan jika ANOVA memiliki efek yang signifikan. Formulasi terbaik adalah sauerkraut dengan konsentrasi garam 2,5%. Selain itu sauerkraut memiliki penurunan berat badan 4,55%, keasaman (pH) 3,70%, kadar air 91,11%, total padatan terlarut 7,40 Brix, vitamin C 3,29 mg / 100 g dan asam laktat 1,86%.  ABSTRACT: Salt is an ingredient that affects the quality of sauerkraut fermentation. Salt is used to remove water from vegetables that are used as lactic acid to grow. Low grade class of cabbage and carrot can be processed sauerkraut to increase economic value. The main of this research was to get concentration of salt that can be preserve the best sauerkraut cabbage and carrot . The research design used was Completely Randomized Design (CRD) with one factor consisting of 4 treatments levels (A1:2,5% ; A2:5% ; A3:7,5% ; A4:10%) and 4 repetitions. Sauerkraut’s quality analized by organoleptic test (hedonic and hedonic quality), physical test (weight loss test), chemical test (pH, water content and total dissolved solids), vitamin C and lactic acid concentration. Data was processed statistically using SPSS application with one way analysis (one ways ANOVA). Duncan’s follow-up was carried out to find out the differences between treatments if ANOVA had a significant effect. The best formulation is sauerkraut with 2,5% salt concentration. In addition sauerkraut has weight loss 4,55%, acidity (pH) 3.70%, water content 91,11%, total dissolved solid 7,40 Brix, vitamin C 3,29 mg/100 g and lactic acid 1,86%. Keywords: Sauerkraut, Salt, Fermentation
PELATIHAN PENYUSUNAN LAPORAN KEUANGAN USAHA KECIL KELOMPOK ANGGOTA PKK PERUM BPP DESA COGREG KECAMATAN PARUNG
Authors: Handriman Tries , Anggraini Dewi
Published: March 2021

Pemberdayaan pengelolaan usaha kecil ini sangat diperlukan, salah satu di bidang pelaporan keuangan usaha, yang dilakukan sesuai dengan standar akuntansi untuk pengusaha kecil dan menengah. Adanya pengabdian masyarakat tentang penyusunan laporan keuangan ini dapat meningkatkan kemampuan usaha kecil, khususnya anggota ibu-ibu PKK di Cogreg agar dapat membuat laporan keuangan sesuai standar akuntansi yang ada. Laporan keuangan yang dihasilkan dapat memberikan informasi kondisi keuangan bisnis yang sedang dijalankan untuk tiap periode pelaporan. Khalayak sasaran strategis yang dilibatkan dalam kegiatan pengabdian ini adalah anggota ibu–ibu PKK. Bentuk dari program pengabdian pada masyarakat ini adalah pelatihan penyusunan laporan keuangan sesuai standar yang ada untuk usaha kecil dan menengah, dalam hal ini berpedoman pada Standar akuntansi. Berdasarkan hasil dan pembahasan kegiatan pengabdian kepada masyarakat, dapat ditarik kesimpulan sebagai berikut: 1) Pemahaman peserta tentang pembuatan laporan keuangan usaha kecil semakin baik setelah mengikuti pelatihan penyusunan laporan keuangan, terutama bagi ibu-ibu PKK dan 2) Kemampuan peserta pelatihan membuat laporan keuangan pada simulasi cukup baik.
SOSIALISASI TEKNOLOGI PRODUKSI BIOGAS TERINTEGRASI DI AGROWISATA BANGKA BOTANICAL GARDEN (BBG) PANGKAL PINANG
Authors: Amelia Julfi Restu
Published: March 2021

Bangka Botanical Garden atau BBG merupakan salah satu icon agrowisata favorit di Bangka Belitung. Salah satu agrowisata yang terdapat di BBG yakni peternakan sapi. Tujuan dari kegiatan ini yakni melakukan sosialisasi dan meningkatkan pemahaman karyawan BBG tentang teknologi biogas terintegrasi, di kawasan agrowisata BBG yang bertujuan dalam mendukung konsep agrowisata berkelanjutan. Metode kegiatan terdiri dari 3 tahap, yakni mengumpulkan data/fakta/informasi, melakukan sosialisasi teknologi peternakan sapi terintegrasi, dan melakukan evaluasi kegiatanHasil sosialisasi menujukkan bahwa setelah mengikuti sosialisasi, peserta sosialisasi memiliki peningkatan pemahaman terhadap pengolahan limbah menjadi pupuk kompos, liquid fertilizer, biogas, dan lainnya. Peserta juga memiliki peningkatan pemahaman dalam teknologi produksi biogas terintegrasi serta memiliki peningkatan keinginan untuk mempelajari lebih lanjut mengenai teknologi produksi biogas terintegrasi dan pemanfaatan dari teknologi tersebut. Hasil sosialisasi juga menujukkan bahwa peserta menginginkan adanya sosialisasi agar dilaksanakan secara berkelanjutan dengan diadakannya pelatihan secara terpadu agar peserta dapat lebih memahami konsep teknologi produksi biogas terintegrasi.
Analisis FEM Dari Suhu HAZ Dengan Pemodelan Sumber Panas Pada Proses Butt-Joint Menggunakan MSC Marc Mentat
Authors: Manurung Rokki , Silitonga Septiani , Hutahaean Yohanes , Manurung Charles S.P , Siagian Parulian , Napitupulu Richard A.M.
Published: March 2021

The success of the welding process is the occurrence of good and strong welding joints that are inseparable from the influence of the heat source. The problem that often occurs when welding is a distortion that can trigger the initial formation of cracks. By predicting the level of welding distortion beforehand, engineers can also reduce the amount of rework by reverse design and distortion margins. That is why with current technological developments it is possible to carry out simulations based on analytical solutions that are implemented through the use of software, where in this study the authors sought to model the temperature of the HAZ region in the Butt Joint process using MSC Marc Mentat. The simulation results show that the heat source is very determining the occurrence of distortion and pressure on the surface. This is caused by the phenomenon of melting and shrinkage that occurs in a short time.
Laju Korosi Pada Baja Karbon Sedang Akibat Proses Pencelupan Pada Larutan Asam Sulfat (H2SO4) dan Asam Klorida (HCl) dengan Waktu Bervariasi
Authors: Tampubolon Miduk , Gultom Roy Ganda , Siagian Lestina , Lumbangaol Partahi , Manurung Charles
Published: March 2021

An experiment has been conducted to determine corrosion rate of medium carbon stell with sulfuric acid solution, Aquades 90,2% + H2SO4 9,8% and hydrochloric acid solution, Aquades 96,8% + HCl 3,2%. By using weight loss method, if medium carbon steel dipped into sulfuric acid solution then the corrosion rate is faster than it dipped into hydrochloric solution. If medium carbon steel dipped in a long time than the corrosion rate slowing down.
Female garment workers' understandings of sexually transmitted infections in selected low to middle-income countries: A systematic review
Authors: Mahmood Shakeel
Published: March 2021

Objective: This study reviewed the current state of knowledge of female garment workers' (FGWs) personal understandings and their experiences of their human immunodeficiency virus (HIV) experiences in selected low to middle-income countries (LMIC).Methods: Relevant literature on FGWs health on sexually transmitted infections (STIs) and HIV within selected LMIC published between 1988 and 2020 carried out, and a systematic review search technique used, utilizing the PRISMA protocol. Significant and relevant information from selected articles obtained and presented existing literature in the method of new outcomes as well as critically interpret existing outcomes. The themes and keywords were examined in the abstract and title of literature extracted using the aforementioned search engines.Results: Major causes of HIV vulnerability of FGWs are poverty (low wages), gender inequality, drug abuse, multiple sex partners, lack of knowledge on STIs/HIV, low use of condoms, and rape violence found in selected LMIC.Conclusion: For empowering FGWs, health education/workplace intervention is crucial, comprising prevention of sexual harassment, workplace violence (WPV), and intimate partner violence (IPV) related training by government sectors, non-government organizations (NGOs), and civil society. A good surveillance system on key populations, including FGWs, and a good public health system in every country is the key and acts very fast for prevention of STIs and HIV on FGWs and contribute to guide policymakers and researchers and improve FGWs health in LIMC.
Aeropalynologic monitoring of air pollution in the Rostov region: the results of the 2019 season
Authors: Churyukina Ella V. , Ukhanova Olga P. , Goloshubova Elena А.
Published: March 2021

BACKGROUND: There is an increase in the proportion of patients suffering from allergic diseases caused by the plant pollen. Aeropalinologic monitoring of the air environment allows us to study the composition of aeroallergens and their role in the formation of pollen allergies. Features of the formation of aerial pollen spectra are closely related to the botanical-geographical and natural-climatic conditions of the region. The Rostov region has its own specific features, which is reflected in the qualitative and quantitative composition of pollen rain.
AIM: To study the dynamics of pollination of allergenic plants in Rostov-on-Don, identify the prevailing taxa and create a calendar of pollination of plants for this region.
MATERIALS AND METHODS: Aeroallergens were detected by using a volumetric Burkard trap. The identification of plant pollen and fungal spores was performed by microscopy of colored slides obtained from a sticky tape covered with a special mixture.
RESULTS: In 2019, 21 taxa were registered in the air environment of Rostov-on-don (trees, meadows, haze, cereals, weeds), fungal spores were found in the air, represented by the mold fungi Cladosporium herbarum and Alternaria alternata in high growing concentrations. An increase in the vegetation period of pollination of trees (07.03.31.06), mares (02.0503.10), cereals (02.0414.09), weeds (18.0728.10) was detected According to the dynamics of pollen concentration, three periods of its growth were registered: spring-summer, summer and summer-autumn. The presence of birch pollen grains in a clinically significant concentration (36 pollen grain (PG)/m3) in this steppe region, an increase in the peak concentration of ragweed (393 PG/m3) in comparison with the same data for 1971 (265 PG/m3) was found.
CONCLUSION: Regional features of the spectrum of air allergens were identified, and a dusting calendar was compiled for Rostov-on-Don.
A clinical case of the X-linked moesin deficiency
Authors: Latysheva Tatiana V. , Latysheva Elena A. , Setdikova Nelly H. , Esaulova Daria R.
Published: March 2021

With the increasing availability of genetic testing, the population of patients diagnosed with CVID breaks down into groups depending on monogenic defects. There is more and more evidence that adults can have combined immunodeficiencies with a late onset.
This article discusses a clinical case of X-linked moesin-associated immunodeficiency (X-MAID). This is a recently described immunodeficiency, which mostly manifests itself at an early age with severe lymphopenia and hypogammaglobulinemia, fluctuating monocytopenia and neutropenia, a weak immune response to vaccine antigens, and increased susceptibility to bacteria and type 3 human herpesvirus.
X-MAID, X-linked immunodeficiency with a recessive mode of inheritance, is caused by genetic defects in the MOESIN gene (membrane organizing spike elongation protein, MSN). Until recently, there were records of 10 people with this mutation, 9 of which have the phenotype of severe combined immunodeficiency (SCID). The patient described in this article has been under observation since the age of 12 and diagnosed with SCID due to an IgG decrease accompanied by infectious-purulent processes of the respiratory tract and diarrheal syndrome.
However, the patient did not entirely fit into the typical clinical picture of CVID due to a severe therapy-torpid papillomavirus infection, the increased number of switched memory B-cells, IgG isolated decrease, persistent severe leukopenia and lymphopenia of CD4+ cells. In accordance with the clinical picture and the results of the immunological examination, combined immunodeficiency was surmised. After a full exome DNA sequencing chrX: g.64951012C T missense type mutation was found in exon 5 of the MSN gene (change in the ENSP00000353408.5:p.Arg171Trp protein). X-MAID was therefore confirmed.
Of the 9 described patients with a similar mutation, 8 had a clinical picture of severe combined immune deficiency. This clinical case confirms the possibility of a milder clinical phenotype development with a late onset under the guise of CVID and shows the need for molecular genetic examination of the adult population of patients with impaired antibody synthesis. The verification of the diagnosis allows not only to determine the prognosis and tactics of the therapy, but also to carry out genetic family counseling and to offer a possibility of giving birth to healthy offspring.
Pharmacological profile of antihistamines: focus on unwanted drug interactions
Authors: Dukhanin Alexander S.
Published: March 2021

Differences between individual antihistamines are determined by such pharmacokinetic properties as the rate and completeness of absorption, half-life, the participation of hepatic and renal mechanisms of elimination from the body. Pharmacodynamic features of the antihistamine include selectivity and affinity for histamine H1-receptors and the presence of central effects. The mechanisms of the development of unwanted drug interactions with second-generation antihistamines are analyzed in detail. Three levels of interaction have been identified: 1) hepatic enzymes of the P450 system; 2) membrane carriers of organic anions (OATP) transport proteins on the sinusoidal membrane of hepatocytes and the luminal membrane of the epithelium of the proximal nephron tubule; 3) P-glycoprotein (Pgp, ABCB1-protein) of epithelial cells of the small intestine the area of absorption of oral forms of antihistamines, the epithelium of the proximal tubule and the BBB (blood-brain barrier). The emphasis is made on the description of the dependence of the pharmacological profile of antihistamines on its chemical structure. The elasticity of the bilastine molecule, the ability to induce a change in conformation underlies the high complementarity of bilastine to the recognition site of the H1-receptor which is a high affinity. Experimental evaluation confirms this conclusion: the dissociation constant (Dс) of the bilastin-receptor complex is in the nM concentration range. The bilastine molecule, as a representative of antihistamines with zwitterionic properties, carries both a positive and a negative charge at a physiological pH, making it difficult for its penetration into the brain. The peculiarities of the chemical nature of the bilastine molecule are reflected in the specific pharmacological profile of AGP. In vitro studies have shown a high specific affinity of bilastine for H1-receptors with a very low affinity for other histamine receptors (H2, H3, H4), serotonin, bradykinin, muscarinic and adrenergic receptors). According to this indicator, bilastine is 3 times higher than cetirizine and 5 times higher than fexofenadine. Bilastine is practically not metabolized in the body and is excreted mainly unchanged, and also does not have a cardiotoxic effect. Bilastine is well tolerated; as a therapeutic dose it has a less pronounced sedative potential compared to other second-generation antihistamines.