bluuebunny/crossref_metadata_2025 huggingface dataset:
Uso de drones y sensores remotos para el monitoreo de laderas: una revisión
Authors: CHAVES PABON SAIETH BAUDILIO
Published: November 2021

Los deslizamientos de tierra son uno de los peligros y riesgos más costoso y fatales para cualquier infraestructura vial, que frecuentemente amenazan e influyen en la situación socioeconómica, principalmente, de los países en vía de desarrollo. Frecuentemente, los estudios de deslizamiento se hacen de manera directa, in situ, siendo muchos de ellos costosos y un reto dada la dificultad que se pueden presentar al acceder a las zonas de estudio. Los datos de los sensores remotos se pueden usar en el monitoreo de deslizamientos de tierra, mapeo, simulación, predicción y evaluación de peligros y otras investigaciones. El presente artículo presenta una revisión bibliográfica en estudios relacionados con el uso de drones y sensores remotos para el seguimiento y monitoreo de laderas, de una manera descriptiva y que permita por medio de la documentación incorporar información relevante para poder abordar futuros estudios más específicos que permitan tener en cuenta el monitoreo de deslizamientos de tierra, las técnicas de sensores remotos, drones y la aplicación global de este conjunto de nuevas tecnologías.
Analysis of the polydispersity of soil-like bodies in glacier environments by the laser light scattering (diffraction) method
Authors: Abakumov Evgeny , Nizamutdinov Timur , Polyakov Viacheslav
Published: November 2021

This study presents the results of polydispersity analysis of soil-like bodies from two various polar regions using the laser light scattering method. The differences in the particle size distribution of cryoconite samples from the Anuchin Glacier (Antarctica) and the Mushketov Glacier (Arctic) are described. The samples obtained from the Mushketov Glacier are characterized by a finer particle size distribution than samples collected on the Anuchin Glacier. While comparing our results with previously published studies, it was found that the method of laser light scattering shows a lower content of small fractions (<0.05 mm) compared to the classical methods of sedimentation, since these methods are based on fundamentally different physical principles. The laser method used requires low amounts of samples (0.2–0.5 g), while the classical sedimentary method uses a higher gravimetric portion of cryoconite (5–10 g), which is critical for field sampling.
Sexual dimorphism patterns of the White Sea threespine stickleback (Gasterosteus aculeatus)
Authors: Dorgham Ahmed , Candolin Ulrika , Ivanova Tatiana , Ivanov Mikhail , Nadtochii Ekaterina , Yurtseva Anastasia , Lajus Dmitry
Published: November 2021

Sexual dimorphism (SD) in the threespine stickleback Gasterosteus aculeatus reflects the different roles of the sexes in reproduction and their adaptations to different ecological niches. We quantified SD in one population of marine stickleback from the White Sea, collected during the spawning period from three spawning grounds, each at a distance of 5 km or less from the others. We used a landmark-based approach to quantify variation in 44 morphometric linear traits. In total, 749 females and 693 males were analyzed. In males, anterior body parts are larger — the base of the caudal fin and armor structures such as the first and second dorsal spines and the pelvic spine. Females have larger posterior bodies — the abdomen, pelvic girdle and the third dorsal spine. The SD of caudal body parts exhibits complex patterns. In White Sea threespine stickleback, SD patterns are generally similar to other populations of the species, but more often show male-biased patterns. Female-biased size SD may be associated with the female biased sex ratio of White Sea stickleback.
Wild-type p53-induced phosphatase sensitizes acute myeloid leukemia cells to conventional chemotherapy
Authors: Golotin Vasily , Belotserkovskaya Ekaterina , Girshova Larisa , Petukhov Alexey , Zaritsky Andrey , Demidov Oleg
Published: November 2021

Recently wild-type p53-induced phosphatase was implicated in the pathogenesis of acute myeloid leukemia (AML) and “pre-leukemia” myeloproliferative conditions. Here we decided to check how the strategy directed to phosphatase inhibition affected sensitivity to conventional chemotherapy. All experiments were conducted on AML cell lines cultivated in vitro. The levels of wild-type p53-induced phosphatase vary in different AML cell lines. The chemical compound GSK2830371 reduced levels of phosphatase and diminished its activity. GSK2830371 did not significantly change the cell cycle distribution of AML cells when used alone or in combination with the anti-cancer chemotherapeutic drug Cytosar but increased caspase-dependent PARP1 cleavage. In contrast with previous studies, we did not observe the negative effect of phosphatase activity inhibition and depletion on cells when a chemical inhibitor was used as monotherapy. Using a combination of GSK2830371 with Cytosar we were able to reduce the threshold of chemotherapy-dependent cytotoxicity and more efficiently eliminate leukemic cells. We propose considering inhibition of wild-type p53-induced phosphatase as a prospective strategy in improving anti-AML therapy.
Composición iónica y comparación de índices de salinidad de suelo agrícola de Texcoco, México
Authors: Santoyo de la Cruz Mario Francisco , Flores Magdaleno Héctor , Khalil-Gardezi Abdul , Mancilla-Villa Óscar Raúl , Rubiños-Panta Juan Enrique
Published: November 2021

Introducción: la salinidad del lago de Texcoco se debe a que éste fue una cuenca endorreica, no tenía forma de lavar las sales. Las causas de salinización de los suelos agrícolas en estas parcelas son: manejo deficiente del riego, uso de aguas de baja calidad para riego y uso excesivo de los fertilizantes químicos. El objetivo de este trabajo fue analizar la composición iónica y comparar la relación de adsorción de sodio-porciento de sodio intercambiable explícita y ajustada de una parcela agrícola.
Método: se hizo un muestreo de suelo para determinar los parámetros de: pH, conductividad eléctrica, calcio, magnesio, sodio, potasio, carbonato, bicarbonato, cloruro y sulfato, de acuerdo con la NOM-021-RECNAT-2000. Además, se realizaron mapas de interpolaciones y curvas de nivel.
Resultados y discusión: de acuerdo con los resultados obtenidos del laboratorio, la parcela es de suelo salino-sódico. Se encontró diferencia significativa entre la relación de adsorción de sodio (RAS) y la relación de adsorción de sodio ajustada, siendo este último el más elevado. Las imágenes interpoladas y las curvas de nivel dan una visión artificial de la relación de adsorción de sodio y el porciento de sodio intercambiable (PSI).
Conclusión: en general, la parcela presenta valores elevados de RAS y PSI. Por lo que en casi toda la parcela existe riesgo de sodicidad. Existen diferencias significativas entre RAS y RAS ajustado, pero no existe diferencia de importancia entre el PSI y el PSI calculado con RAS ajustado. La clasificación RAS-CE, en la mayoría de los casos, presenta suelos de salinidad muy alta y sodicidad media (C4-S2).
Situation of menstrual management facilities in schools of peri-urban areas of Nepal: WASH, privacy, and healthcare
Authors: Shrestha Sadhana , Shrestha Salina , Ito Yuri , Kobayashi Yuka , Nishida Kei , Futaba Kazama , Malla Rabin
Published: November 2021

Menstrual management (MM) facilities in schools are neglected in low- and middle-income countries. We examined the existing MM facilities, identified the deficient, and collected students' ideas in peri-urban schools of Nepal. The schools had basic MM facilities including water sanitation and hygiene (WASH) infrastructures, gender-segregated toilet facilities with taps, dustbins and running water, provision of emergency sanitary pads, etc. Out of 71 students who reported soiling of dresses with menstrual blood as a common problem, 27% went home and did not return in such situation instead of washing off at school. Forty-six per cent of students used washable absorbents, but washing and drying facilities were lacking, and students adapted by using disposable pads at school and washable at home. Out of 126 students, 106 took days off during menstruation in the past three months with an average of 2.6 days by one student. Sixty-one per cent gave the reason as pain and 39% tiredness for taking days off. Healthcare facilities were lacking in schools, hence, lack of these facilities in schools might be contributing to absenteeism. The traditionally advocated list of MM facilities for schools, largely involving WASH facilities, should be updated, including newly identified factors which were also suggested by students.
Anticipated maximum scale precipitation for calculating the worst-case floods
Authors: Takeuchi Kuniyoshi , Tanaka Shigenobu
Published: November 2021

Against increasing number of unprecedented heavy rains and typhoons reflecting climate change, the Japanese Government decided saving life as the top priority considering a ‘worst-case’ scenario. Accordingly, the Flood Risk Management Act was amended in 2015 to use the anticipated maximum scale precipitation (AMSP) for flood inundation calculation. In order to estimate the AMSP, the Ministry of Land, Infrastructure, Transport and Tourism (MLIT) chose historical maximum areal precipitation in the form of duration–area–depth (DAD) curves rather than climate change projections' dataset d4PDF. In this paper, policy development and detailed estimation procedures for the AMSP were reviewed and discussed. It was concluded that the current climate change projections are still not accurate enough to be used as the basis for real local operations, while long accumulated ground observations and ground-based radars are available in good quality all over Japan. But at the same time, historical maximum should always be updated as past records are renewed. Also, regional partitioning should not be done at too coarse of scale for proper regionalization of DAD. Such strategy would serve as a useful reference for other nations.
Infrastructure capacity planning for reducing risks of future hydrologic extremes
Authors: Boland John J. , Loucks Daniel Peter
Published: November 2021

Floods and droughts and their associated economic, environmental, and social losses or damages are increasing in severity and frequency. Measures taken to reduce these losses or damages stemming from extreme events typically depend on how effective they are in reducing the consequences of having either too much or too little water and for longer periods of time. To identify trade-offs between the annual estimated loss or damage reduction, i.e., the benefits, however measured, and the average annual cost of various damage reduction measures, one can perform risk–cost analyses. Because of climate change, the likelihoods of future hydrologic extremes are both changing and uncertain. Also uncertain are any estimates of future damages that would occur given any specific extreme event. In addition, one cannot be certain of the future costs or benefits of damage reduction measures. This paper outlines a range of practical approaches for identifying these trade-offs, taking into account the uncertainties associated with future damages resulting from any specific flood or drought event, the changing uncertainties of future flood and drought events, and the uncertainty of future damage mitigation costs.
Integrated experimental and theoretical insights for Malachite Green Dye adsorption from wastewater using low cost adsorbent
Authors: Ibrahim EL-Shimaa , Moustafa H. , El-molla Sahar A. , Abdel Halim Shimaa , M. Ibrahim Shaimaa
Published: November 2021

Water pollution is one of the problems that threaten humanity, and to confront it with only experimental procedures is not enough. It is necessary to integrate both practical methods and theoretical calculations to achieve decontamination with the most accurate interpretation. Hence, discussing the experimental mechanism study of Malachite Green (MG) dye adsorption with the help of the application of density functional theory (DFT) calculations is the main goal of this article. The experimental results affirmed that the preparation of γ-Al2O3 by precipitation method using (NH4)2CO3 improved the porosity, the surface capability, and the adsorbent capacities (qmax = 210 mg/g) at optimum condition compared with the previous studies. Kinetic and equilibrium studies showed that the adsorption follows the pseudo-second-order model and Freundlich isotherm model, respectively. Also, the calculated and observed thermodynamic parameters exerted positive values of ΔH° and ΔS°, which translates into an endothermic process with increasing disorder of the system. Theoretical calculations at DFT- B3LYP/6-31G (d,P) level of theory were calculated to show the selectivity of using the cationic form of MG in the experimental measurements to find the interaction mechanism. The electronic structure and intramolecular charge transfer of MG, its cationic form and the complex of MG-Al were investigated theoretically at the B3LYP/6-31 G (d,p) level of theory. The equilibrium geometries of MG, its cationic form and the complex of MG-Al were determined, and it was found that these geometries are non-planar. The EHOMO and ELUMO energies can be used to calculate the global properties; chemical hardness (η), softness (S) and electronegativity (χ). The calculated non-linear optical parameters (NLO) of the studied compounds, the electronic dipole moment (μ), first-order hyperpolarizability (β), the hyper-Rayleigh scattering (βHRS) and the depolarization ratio (DR), showed promising optical properties. Finally, the computational and the experimental results indicated that the adsorption efficiency of MG from wastewater was directly associated with the dye electrophilicity power.
Dynamic and equilibrium precipitation of struvite from the concentrated cellulosic ethanol stillage
Authors: Zhang Qiqi , Hogen Tobias , Zhou Kuangxin , Berendts Stefan , Hu Kang , Zhang Yongjun , Geißen Sven-Uwe
Published: November 2021

The phosphate rock mineral is the main source of P-fertilizer production. It is estimated to become depleted in next century. Thus, the recovery of phosphorus from waste streams has attracted great interest. The cellulosic ethanol production is seen as more and more important in future. During the production of cellulosic ethanol, the phosphorus element is released from lignocellulosic biomasses and ends up dissolved as phosphate ions in the stillage stream. In this study, the struvite (MgNH4PO4 · 6 H2O) recovery from the concentrated cellulosic ethanol stillage (ES) was conducted under room conditions with an initial pH at 7–9. The effect of Mg2+, PO43−, NH4+ and Ca2+ during struvite precipitation tests was investigated. The optimized pH value for struvite recovery is estimated at 8.5, by which 85% of PO43− and 46% of Mg2+ are removed from the liquid stream. The mass fraction of struvite in recovered crystal sample reaches 82 wt.%. The economic evaluation of struvite recovery from ES was also investigated. This work proves that the struvite is potentially to be recovered with high purity from the concentrated cellulosic ethanol stillage.
Entre lo irracional y la defensa del honor: los crímenes pasionales durante el Porfiriato
Authors: Goretty Venegas Águeda , Rodríguez Josalath
Published: November 2021

Durante el Porfiriato (1876-1911) apareció en la prensa mexicana un nuevo tipo de crimen: el pasional, que al poco tiempo las crónicas sobre éste acapararon las páginas. Estos delitos resultaron ser un desafío para el discurso de la criminalidad positivista que propagaba el Estado porque evidenciaba que no solo las clases populares participaban sino, también, los miembros de la élite. Este artículo recupera la prensa como fuente primaria, en concreto los casos pasionales con el objetivo de analizar dos variables: 1) Crímenes cometidos por las clases populares donde se resaltaba que los cometían como parte de su ignorancia, el abuso de sustancias prohibidas y bebidas alcohólicas, las formas de relacionarse amorosamente y la condición humilde de los participantes; y, 2) Crímenes cometidos por la élite, los cuales fueron justificados por la defensa del honor y el cuidado de las buenas costumbres, para ello fueron relatados como historias de amor rosa.
Non-coding RNA-Encoded Peptides/Proteins in Human Cancer: The
Future for Cancer Therapy
Authors: Bakhti Seyedeh Zahra , Latifi-Navid Saeid
Published: November 2021

:

Although non-coding RNAs (ncRNAs) were initially thought to be a class of
RNA transcripts with no encoding capability, it has been established that some ncRNAs
actually contain open reading frames (ORFs), which can be translated into micropeptides
or microproteins. Recent studies have reported that ncRNAs-derived micropeptides/
microproteins have regulatory functions on various biological and oncological processes.
Some of these micropeptides/microproteins act as tumor inhibitors and some as
tumor inducers. Understanding the carcinogenic role of ncRNAs-encoded micropeptides/
microproteins seems to pose potential challenges to cancer research and offer promising
practical perspectives on cancer treatment. In this review, we summarized the present
information on the association of ncRNAs-derived micropeptides/microproteins with
different types of human cancers. We also mentioned their carcinogenic mechanisms in
cancer metabolism, signaling pathways, cell proliferation, angiogenesis, metastasis, and
so on. Finally, we discussed the potential clinical value of these micropeptides/
microproteins and their potential use in the diagnosis and treatment of cancer. This
information may help discover, optimize, and develop new tools based on biological micropeptides/
microproteins for the early diagnosis and development of anticancer drugs.
Elevated Circulating Thrombomodulin Levels in Systemic Lupus Erythematosus: A Systematic Review and Meta-Analysis
Authors: Hu Yu-Qian , Wang Zhi-Xin , Xiang Kun , He Yi-Sheng , Feng Ya-Ting , Shuai Zong-Wen , Pan Hai-Feng
Published: November 2021

Objectives:

Thrombomodulin (TM) is closely related to the pathogenesis of autoimmune diseases, including
systemic lupus erythematosus (SLE). However, current evidence on circulating TM levels in SLE patients
is contradictory. We conducted this meta-analysis to more accurately assess circulating TM levels in patients
with SLE and lupus nephritis (LN) and to analyze related influencing factors.

Methods:

Systematic search of relevant documents was conducted in PubMed, Embase, and The Cochrane Library
databases (up to 28 February 2021). Studies on the comparison of circulating TM between SLE patients
and controls were screened and evaluated for inclusion. Random-effects model analysis was applied to calculate
the combined standardized mean difference (SMD) with a 95% confidence interval (CI). Heterogeneity
was estimated by Q statistics and I2.

Results:

A total of 353 articles were identified, 14 provided adequate information for this study finally. The results
illustrated that SLE patients had higher TM levels than healthy controls (SMD=0.38, 95% CI: 0.02 to
0.74, p=0.04). Circulating TM levels were increased in patients with active SLE compared to inactive SLE patients
(SMD=1.12, 95% CI: 0.03 to 2.20, p=0.04). In addition, circulating TM levels of SLE patients with LN
were higher than those without LN (SMD=4.55, 95% CI: 1.97 to 7.12, p=0.001).

Conclusions:

The circulating TM levels in SLE patients are enhanced. In addition, circulating TM levels may be
practical in reflecting the disease activity and nephritis involvement of SLE patients.
Recent Developments in Mesoporous Silica Nanoparticles for Tumor Theranostic Applications
Authors: Wang Xuerui , Zheng Mengyuan , Raza Faisal , Liu Yuhao , Wei Yiqi , Qiu Mingfeng , Su Jing
Published: November 2021

:

Due to the advantages of adjustable pore size, easy surface modification, high biocompatibility, and
so on, mesoporous silica nanoparticles (MSNs) have attracted significant attention. Moreover, they are widely
used in the fields of biology and medical research, mostly focusing on drug and gene delivery and bioimaging.
This review introduces several commonly used synthetic methods of MSNs and the latest progress of MSNs in
tumor therapy and diagnosis, mainly including the study about modified MSNs as drug carriers and the application
of MSNs in bioimaging. The deficiencies of MSNs’ application and prospects for its future clinical transformation
are also discussed.
1,3,4-thiadiazole: A Privileged Scaffold for Drug Design and Development
Authors: Han Xu , Yu Yun Long , Hu Yang Sheng , Liu Xin Hua
Published: November 2021

1,3,4-thiadiazole is a five-membered aromatic heterocycle containing two nitrogen atoms
and one sulfur atom. As a privileged scaffold, it has its unique chemical properties and biological
characteristics. In the design of drugs, they are widely and flexibly applied by medicinal chemists,
and many candidates with therapeutic prospects have been developed. In this review, we focus on
1,3,4-thiadiazole derivatives and their various biological activities reported in the past five years
(from 2015 to early 2020), such as anticancer, antibacterial, antifungal, anti-tuberculosis, antiinflammatory,
antivirus, anti-leishmania and other functions. It is believed that this review can provide
some new ideas for seeking rational design to develop 1,3,4-thiadiazole based medicinal agents
with better activity and lower toxicity.
Changes in John Cunningham Virus Index in Multiple Sclerosis Patients
Treated with Different Disease-Modifying Therapies
Authors: Patti Francesco , Sgarlata Eleonora , Chisari Clara Grazia , Toscano Simona , Finocchiaro Chiara , Lo Fermo Salvatore , Millefiorini Enrico
Published: November 2021

Background:

Progressive Multifocal Leukoencephalopathy (PML) is an opportunistic
infection caused by John Cunningham virus (JCV) reactivation, potentially associated with natalizumab
(NTZ) treatment for Multiple Sclerosis (MS). The anti-JCV antibodies titre (JCV index) increases
during NTZ treatment; however, the effects of other disease-modifying therapies (DMTs) on
the JCV index have not been fully explored.

Objective:

The aim of the study was to evaluate changes in the JCV index during treatment with
several DMTs.

Methods:

This longitudinal study evaluated the JCV index before starting DMT (T0) and during
treatment with DMT (T1).

Results:

A total of 260 participants (65.4 % females, mean age 43 ± 11.3 ) were enrolled: 68 (26.2
%) treated with fingolimod (FTY), 65 (25 %) rituximab or ocrelizumab (RTX/OCR), 37 (14.2 %)
dimethyl-fumarate (DMF), 29 (11.2 %) cladribine (CLD), 23 (8.8 %) teriflunomide (TFM), 20 (7.7
%) interferon or glatiramer acetate (IFN/GA), and 18 (6.9 %) alemtuzumab (ALM). At T1, the percentage
of patients with JCV index <0.90 was found to be significantly increased in the ALM group
(16.7 % versus 66.7 %, p = 0.05), while the percentage of patients with JCV index >1.51 was found
to be significantly reduced in the RTX/OCR group (51.6 % versus 37.5 %, p = 0.04). In the FTY
group, a significant reduction in the percentage of patients with JCV index <0.90 was also found
(23.5 % versus 1.4 %, p = 0.0006). The mean JCV index was reduced in the RTX/OCR and ALM
groups, while a significant increase was observed in the FTY group.

Conclusion:

DMTs with a T and/or B depleting mechanism of action induced a significant reduction
in the JCV index. These results may suggest new possible sequencing strategies potentially
maximizing disease control while reducing the PML risk.
Sex-Specific Association between Antioxidant Defense System and Therapeutic
Response to Risperidone in Schizophrenia: A Prospective Longitudinal
Study
Authors: Liu Haixia , Liu Hua , Jiang Shuling , Su Lei , Lu Yi , Chen Zhenli , Li Xiaojing , Li Xirong , Wang Xuemei , Xiu Meihong , Zhang Xiangyang
Published: November 2021

Background:

There are various differences in response to different antipsychotics and
antioxidant defense systems (ADS) by sex. Previous studies have shown that several ADS enzymes
are closely related to the treatment response of patients with antipsychotics-naïve first-episode
(ANFE) schizophrenia.

Objective:

Therefore, the main goal of this study was to assess the sex difference in the relationship
between changes in ADS enzyme activities and risperidone response.

Methods:

The plasma activities of glutathione peroxidase (GPx), catalase (CAT), superoxide dismutase
(SOD), and total antioxidant status (TAS) were measured in 218 patients and 125 healthy
controls. Patients were treated with risperidone for 3 months, and we measured PANSS for psychopathological
symptoms and ADS biomarkers at baseline and at the end of 3 months of treatment.
We compared sex-specific group differences between 50 non-responders and 168 responders at
baseline and at the end of the three months of treatment.

Results:

We found that female patients responded better to risperidone treatment than male patients.
At baseline and 3-month follow-up, there were no significant sex differences in TAS levels and
three ADS enzyme activities. Interestingly, only in female patients, after 12 weeks of risperidone
treatment, the GPx activity of responders was higher than that of non-responders.

Conclusion:

These results indicate that after treatment with risperidone, changes in GPx activity
were associated with treatment response, suggesting that changes in GPx may be a predictor of response
to risperidone treatment in female patients with ANFE schizophrenia.
A Concise Overview on Recent Advances in Pharmaceutical Aerosols and
their Commercial Applications
Authors: Mishra Raghav , Agarwal Radhika
Published: November 2021

Background:

Localized drug delivery to the respiratory system has become an increasingly
successful and essential treatment strategy for several pulmonary diseases, including asthma,
chronic abstractive disease, pneumonia, bronchitis, and cystic fibrosis. The rising incidence
of respiratory diseases is a significant factor driving the worldwide market for respiratory inhaler
devices.

Objective:

The objective of this article is to present various aspects of pharmaceutical aerosols,
including their types, components, fundamentals, in-process and finished product quality control
tests based on pharmacopeial standards and specifications, and commercial utility considering the
pharmaceutical aerosol dosage forms that have been patented from 2000 to 2020, along with a list
of marketed pharmaceutical products.

Method:

Aerosol, collectively referred to as a pressurized device, operates by triggering an appropriate
valve system with a continuous or metered dosage of tiny mist spray. It is used not only
in the treatment of asthma and chronic obstructive pulmonary disease but also in the treatment of
cancer, diabetes, migraine, angina pectoris, acute lung injury, bone disorders, tuberculosis, and
many more. A multitude of different variables, including types and properties of propellants, active
substances, containers, valves, actuators, spray patterns, valve crimping efficiency, and particle
size of the aerosols, influence the therapeutic effectiveness of pharmaceutical aerosols.

Conclusion:

Based on the current findings, distinct characteristics such as the elimination of firstpass
metabolism, quick drug absorption, ease of therapy termination, as well as a larger surface
area have attributed to the success of pharmaceutical aerosols.
Legal aspects of gender identity in Ukraine
Authors: Piddubnyi Oleksii Yu. , Marits Dariia O. , Yehorova Valentyna S. , Chepulchenko Tetiana O. , Vladykin Oleksandr N.
Published: November 2021

The issue of gender identity in the modern world is becoming increasingly relevant. The place of a person's right to recognise their gender identity in the Ukrainian legal plane is uncertain. The study considers the specific features of regulating the human right to recognise gender identity and gender reassignment in Ukraine. The authors of the study consider personal non-property rights of an individual as a specific concept, and somatic rights – as a generic concept, the main meaning of which is the ability to dispose of one's body. Accordingly, a person's right to recognition of their gender identity is a personal non-property right. In Ukraine, legal regulation of gender change is carried out, but certain regulations come into force only in the event of a legal fact of gender change, although their provisions regulate the direct implementation of such a right. However, gender identity is the third most common cause of discrimination. It is necessary for Ukrainian legislation to update the regulatory framework that governs the procedure for changing gender. It is worth paying attention to the correct use of terminology in these relations.
graphic novel as a popular genre of book publishing in the context of modern design
Authors: Oliinyk Viktoriia
Published: November 2021

The relevance of the research is due both to the lack of research that would comprehend a graphic novel as an independent phenomenon and subject of art history, the youth of the genre, and its relative non-proliferation in the Ukrainian literary space. The vast majority of Russian publications touch on the analysis of specific graphic novels in the context of modern literary studies, which focuses on the narrative and ideological components of individual works without taking into account the role of the visual component for the genre as a whole. In this regard, the article is aimed at identifying the essence of the graphic novel, its differences from the classic for book design relationships of illustration and text, clarifying the nature and role of its communication and semantic saturation taking into account the functions of design as a form of communication, highlighting the unique characteristics of the genre against the background of the traditional genre means and searching for the information and aesthetic potential of the graphic novel in the practice of Ukrainian book design.
Determinants of Current Account Balance in ASEAN+6
Authors: Purnama Dewi , Budiono Budiono , Priyono Anhar Fauzan
Published: November 2021

Abstract: The phenomenon of global current account imbalance has made researchers and policy makers provide more attention on current account issues. This phenomenon is illustrated by the US' current account deficit which continues to increase, while ASEAN+6 reaps a surplus. This study aims to study the factors that affect the aggregate current account in ASEAN+6 that have not been explained by previous studies. Based on the dynamic panel model (GMM) used, it was found that the variables Lagged-current account, ToT, Exchange Rate Stability, and Household Consumption have a significant effect on the aggregate current account in ASEAN+6. On the other hand, the REER and Government Expenditures do not have a significant effect on the ASEAN+6 current account. The benefit of this research is that it can be used for the formulation of current account policies to minimize the government's efforts to overcome a bigger issue: imbalance in balance of payment.Keywords: Current account balance, Generalized Method of Moment, ASEAN+6 Determinan Neraca Transaksi Berjalan di ASEAN+6Abstrak: Fenomena ketidakseimbangan transaksi berjalan global telah membuat para peneliti dan pembuat kebijakan memberikan perhatian lebih pada masalah transaksi berjalan. Fenomena ini tergambar dari defisit transaksi berjalan AS yang terus meningkat, sedangkan ASEAN+6 menuai surplus. Penelitian ini bertujuan untuk mempelajari faktor-faktor yang mempengaruhi neraca transaksi berjalan agregat di ASEAN+6 yang belum dijelaskan oleh penelitian-penelitian sebelumnya. Berdasarkan model panel dinamis (GMM) yang digunakan, ditemukan bahwa variabel Lagged-current account, ToT, Exchange Rate Stability, dan Household Consumption berpengaruh signifikan terhadap agregat current account di ASEAN+6. Di sisi lain, REER dan Belanja Pemerintah tidak berpengaruh signifikan terhadap transaksi berjalan ASEAN+6. Manfaat dari penelitian ini adalah dapat digunakan untuk perumusan kebijakan transaksi berjalan untuk meminimalkan upaya pemerintah mengatasi masalah yang lebih besar: ketidakseimbangan neraca pembayaran.Kata kunci: Neraca transaksi berjalan, Generalized Method of Moment, ASEAN+6
Prediction of Entrepreneurial Intention and Pre-Start-Up Behaviours on Entrepreneurial Concentrated Students
Authors: Octaviani Fiesta , Renaldi Renaldi , Sihombing Sabrina Oktaria
Published: November 2021

Abstract: This study aims to examine the factors that have the potential to influence student’s entrepreneurial intentions using the TPB theory model along with several other factors (i.e., attitude towards entrepreneurship, subjective norms, perceived behavioral control, innovation, proactive personality, need for achievement, internal locus of control, risk taking propensity, lifestyle integration, social networking, resources, opportunity recognition, fungibility issues, entrepreneurial intention, and pre-start-up behavior). Data were collected through 222 entrepreneurship concentration students from well-known universities in Indonesia. The structural equation model (PLS-SEM) was applied to test the research hypotheses. The emergence of significant and positive results among all factors involved, except fungibility issues is evidence of the positive influence of the factors studied on student’s entrepreneurial intentions in Indonesia which are then briefly summarized in the form of conclusions. Keywords: Entrepreneurial intention, theory of planned behavior, pre-start-up behavior, entrepreneurship Prediksi Entrepreneurial Intention dan Pre-Start-Up Behaviour terhadap Mahasiswa Konsentrasi KewirausahaanAbstrak: Penelitian ini bertujuan untuk menguji faktor-faktor yang berpotensi mempengaruhi niat berwirausaha mahasiswa dengan menggunakan model teori TPB beserta beberapa faktor lainnya (yaitu sikap berwirausaha, norma subjektif, persepsi pengendalian perilaku, inovasi, kepribadian proaktif, kebutuhan berprestasi, internal. locus of control, kecenderungan mengambil risiko, integrasi gaya hidup, jejaring sosial, sumber daya, pengenalan peluang, masalah kesepadanan, niat kewirausahaan, dan perilaku pra-start-up). Pengumpulan data dilakukan melalui 222 mahasiswa konsentrasi kewirausahaan dari universitas ternama di Indonesia. Model persamaan struktural (PLS-SEM) digunakan untuk menguji hipotesis penelitian. Munculnya hasil yang signifikan dan positif di antara semua faktor yang terlibat, kecuali masalah kesepadanan merupakan bukti pengaruh positif dari faktor-faktor yang diteliti terhadap niat berwirausaha mahasiswa di Indonesia yang kemudian dirangkum secara singkat dalam bentuk kesimpulan.Kata kunci: Niat kewirausahaan, teori perilaku terencana, perilaku-pra-start-up, kewirausahaan
Disclosing the Regeneration of Endek Weaving Craftsmen in Bali
Authors: Martini Ida Ayu Oka , Gorda A.A.N Eddy Supriyadinatha , Gorda A.A.N. Oka Suryadinatha , Purnama Sari Desak Made Febri
Published: November 2021

Abstract: This study aims to investigate the regeneration of endek weaving craftsmen in Klungkung, Bali. The research method used is descriptive qualitative research. The research location is in Klungkung, Bali. The technique of collecting data through interviews was conducted on four groups of informants, namely business owners, craftsmen, children of craftsmen, and community leaders. The data analysis technique used is the interactive model of Miles and Huberman, namely: data reduction, data display, and verification. The results showed that regeneration attempts have not yet been successful due to several factors, including: 1) the younger generation’s lack of interest in weaving, 2) the number of promising job alternatives, and 3) the lack of love and pride in the younger generation for endek woven fabric products. The regeneration process functions through outreach carried out by networks of family, friends, and neighbors.Keywords: regeneration, socialization, weaving Mengungkap Regenerasi Pengrajin Tenun Endek di BaliAbstrak: Penelitian ini bertujuan untuk mengetahui regenerasi pengrajin tenun endek di Klungkung, Bali. Metode penelitian yang digunakan adalah penelitian kualitatif deskriptif. Lokasi penelitian berada di Klungkung, Bali. Teknik pengumpulan data melalui wawancara dilakukan terhadap empat kelompok informan yaitu pemilik usaha, pengrajin, anak pengrajin, dan tokoh masyarakat. Teknik analisis data yang digunakan adalah model interaktif Miles dan Huberman yaitu: reduksi data, display data, dan verifikasi. Hasil penelitian menunjukkan bahwa upaya regenerasi belum berhasil karena beberapa faktor, antara lain: 1) kurangnya minat generasi muda dalam menenun, 2) banyaknya alternatif pekerjaan yang menjanjikan, dan 3) kurangnya rasa cinta dan bangga pada yang lebih muda. generasi untuk produk kain tenun endek. Proses regenerasi berfungsi melalui sosialisasi yang dilakukan oleh jaringan keluarga, teman, dan tetangga. Kata kunci: regenerasi, sosialisasi, tenun
Digital Medical Interview Assistant AnCha for Obtaining the Medical History in General Medicine: Case study (Preprint)
Authors: Regli Selina Florence , Gashi Floriana , Denecke Kerstin
Published: November 2021

BACKGROUND

Collecting information on the medical history of a patient is an important step during the diagnosing process. Besides the interrogation by the physician, computerized questionnaires are used to collect the data. To facilitate interaction, implementation of digital medical interview assistants (DMIA) using conversational user interfaces (CUI) gain in interest.

OBJECTIVE

The aim of this research is to assess patient’s and physician’s perceptions towards a DMIA with CUI. Beyond, we want to understand how such DMIA can be used in real-world context, what issues and barriers exist in their usage.

METHODS

We developed a web-based DMIA with CUI (referred to as AnCha for anamnesis chatbot) as a research prototype in a participative and iterative development process. We conducted a pilot trial in a practice for general medicine. Patient perceptions were collected and physicians were interrogated regarding usefulness of collected information.

RESULTS

31 patients were approached, and 9 participants were included in the pilot trial; 3 conversation protocols were used by the physicians to prepare for the encounter. Participants spanned all age groups from digital natives (n=5), and digital workers (n=3) to digital seniors (n=1). Patients can easily interact with AnCha and are willing to provide information to the digital tool. They recognize benefits while using the dialog system compared to the existing process. Important insights into practical implementation and integration into practice workflows could be gained.

CONCLUSIONS

Providing information on complaints and medical history before the actual encounter is considered useful. In order to be supportive for physicians, information has to be made available in a sufficient time frame before the encounter. Future work has to assess in particular whether AnCha is also well accessible for digital seniors.
Selection Method of Network Ideological and Political Education Resources under Big Data
Authors: Zhang Siqi
Published: November 2021

The continuous development of network information technology has prompted people to use big data to process information in order to improve work efficiency. All kinds of data are affecting people’s lives. Under the background of the big data era, college students’ values, studies and lifestyles, and access to information have changed obviously. Therefore, colleges and universities should make full use of the convenience of information in the era of big data to improve the informatization of ideological and political work in colleges and universities. The ideological consciousness and values of contemporary college students are strongly impacted by big piece of data. Based on the characteristics of big data, this paper conducts research and analysis on ideological and political education in colleges and universities in the era of big data, and makes full use of network resources to improve the ability of ideological and political education.
Conocimiento sociodemográfico y respuesta institucional a una pandemia. El caso de México
Authors:   Universidad Nacional Autónoma de México, Welti-Chanes Carlos , Ramírez-Penagos Alfonso C. ,   Universidad Nacional Autónoma de México
Published: November 2021

El artículo hace evidente la necesidad de tomar en cuenta las características de los grupos de-mográficos que conforman un país y el entorno de una sociedad globalizada que interactúa con ella, para tomar decisiones debidamente fundadas con el objetivo de enfrentar un fenómeno, cuyas consecuencias pueden ser catastróficas como es el caso de una pandemia. El texto hace referencia a la respuesta no farmacológica a una pandemia para disminuir el nivel de contagios entre la población y que incluye medidas como el aislamiento social, la cuarentena y el cierre parcial o total de áreas en las que se desarrollan actividades que implican la interacción en tiempo real entre personas y que involucran contacto físico, lo que hace necesario evaluar los posibles efectos, derivados de su ubicación socialmente estructurada en organizaciones como la empresa, la escuela o la familia. Las políticas públicas para enfrentar la pandemia son el núcleo central del análisis y, específicamente, las acciones gubernamentales que se diseñan o se deberían diseñar en diversos ámbitos, y que se ponen a funcionar a través de organizaciones concretas con este objetivo. También los roles de la familia y las organizaciones que forman parte del mercado son analizados en este contexto.
Respuesta frente al Covid-19 para la atención de la población migrante mexicana en el sur de Estados Unidos
Authors:   El Colegio de la Frontera Norte, López-Jaramillo Ana María , Rangel-Gómez María Gudelia ,   El Colegio de la Frontera Norte, Cruz-Piñeiro Rodolfo ,   El Colegio de la Frontera Norte
Published: November 2021

Una de las interrogantes actuales es sobre el impacto de la pandemia causada por la Covid-19, SARS-CoV-2 sobre los grupos de personas de mayor vulnerabilidad. En general se ha documen-tado que la pandemia está afectando de manera desigual a diferentes poblaciones. Por ello, este trabajo exploratorio indaga sobre el impacto que está teniendo el Covid-19 sobre la población de inmigrantes mexicanos que residen en Estados Unidos. Para ello, se considera una muestra de migrantes mexicanos que han sido atendidos a través del Programa de Unidades Móviles de Salud y Bienestar de la Comisión de Salud Fronteriza México-Estados Unidos en las ciudades de Phoenix y Tucson, Arizona. El trabajo también explora y analiza las primeras acciones realizadas en la región fronteriza por los actores gubernamentales de ambos países. Entre los resultados se destaca que más de la mitad de la población reportó tener diabetes mellitus, una alimentación moderada o alta en grasas y azúcares y poca actividad física; así también se observó que son una población con una estancia promedio en Estados Unidos de alrededor de 12 años, con un nivel menor a la preparatoria y bajo nivel de inglés, y labora en ocupaciones de baja remuneración salarial.
Online Job Portal- A Better Way for Finding Jobs in the COVID-19 Pandemic
Authors: Dave Chitrak Vimalbhai
Published: November 2021

Abstract: Due to the COVID-19 pandemic unemployment broke all the previous records. Due to the pandemic students cannot go to colleges and have no option of campus placements. The only option available for them is to find a job through online job portals. In this paper we present the online recruitment framework that enables different companies to post their job vacancies, which jobseekers can consider while searching for jobs. This portal can also capture job requirements dependent on employers’ needs. A survey was conducted to identify the problems and requirements of the users with the current job portals and the findings of the survey are incorporated in this portal. The main aim of this job portal is to connect the employers and jobseekers as an e-recruitment to help jobseekers find the right jobs. Keywords: Job Seeker, Employer, Online Job Portal, Online Recruitment, Knowledge Sharing, COVID-19 Pandemic
API Development Teaching- Learning Platform
Authors: Sutar Gurudev
Published: November 2021

Abstract: API (Application Programming Interface) is a sequence of commands, rules, or regulations that enables a software or app to leverage attributes from another application, system, or gadget to improve its own services. In a nutshell, it's a feature that allows apps to connect with one another. The IT industry has a high demand for REST API Development, hence this article provides an interactive teaching and learning platform for REST API Development. Using the LBD (Learning By Doing) concept, the suggested platform seeks to assist users in learning REST API Development. This tool would assist users in learning to design their own APIs by requiring them to practise (either through coding or MCQs). The platform would be based on selfevaluation and reflection models of self-regulated learning, allowing users to learn more effectively. The platform would also try to provide some scaffolding for users that fail test cases, such as assistance in debugging and why they might be failing the test cases. Keywords: REST-API, Teaching Learning Platform, Self-Regulated Learning(SRL), Human Computer Interaction(HCI), Dashboard, Learning by doing(LBD)
Las órdenes de protección como herramienta para combatir la violencia hacia las mujeres en el marco de la (ex)pareja: fundamentos, marco jurídico y aplicación en Uruguay
Authors: Gambetta Victoria , Russo Cecilia , Fonseca Agustina
Published: November 2021

El objetivo de este artículo es introducir a las órdenes de protección como el principal instrumento legal para evitar que las mujeres que han sufrido violencia en el marco de una pareja actual o previa sean nuevamente victimizadas. Para ello, se describe el proceso de reconocimiento jurídico de la violencia hacia las mujeres en Latinoamérica y el Caribe, introduciendo aportes desde el feminismo jurídico. Luego se enumeran los beneficios esperados de las órdenes de protección para prevenir la revictimización de las mujeres, y se describe cómo este espíritu ha sido materializado en el marco jurídico de los países del Cono Sur. Finalmente, se realiza una descripción detallada de la naturaleza de las órdenes de protección en Uruguay, denominadas medidas cautelares, y del circuito institucional que cada caso de violencia conyugal hacia las mujeres recorre desde la radicación de la denuncia de violencia doméstica hasta el seguimiento policial de las medidas.
El estudio del derecho desde un enfoque complejo y transdisciplinar: experiencias de investigación en políticas de juventud en Argentina
Authors: Becher Yussef
Published: November 2021

La finalidad del artículo es ofrecer una propuesta conceptual sobre el derecho. Se recurre a una teoría epistemológica de trayectoria que conduce a observar la realidad desde su complejidad. Asimismo, conlleva ciertos presupuestos al momento de la construcción de la ciencia, en particular, su inter o transdisciplinariedad. La disciplina jurídica ha estado históricamente vinculada al positivismo, lo cual la aproximó, según ciertas posturas, a los cánones instituidos sobre lo académico. No obstante, se la critica por un supuesto distanciamiento de lo que sucede en situaciones o contextos sociales particulares. Además, se brindan resultados de investigación —en el marco de dos tesis de posgrado— que han incorporado aspectos de los antes enunciados a través del análisis de los efectos de regulaciones estatales sobre políticas sociales para jóvenes: la Asignación Universal por Hijo para Protección Social (auh) y el Programa de Respaldo a Estudiantes Argentinos (Progresar). En consecuencia, la intención del aporte es propiciar saberes según un prisma socio-jurídico.