bluuebunny/crossref_metadata_2025 huggingface dataset:
Juventudes, escuela y E.S.I.: una mirada crítica
Authors: González Cuba Florencia
Published: June 2024

El presente trabajo teórico-ensayístico se propone reflexionar acerca del rol de las instituciones educativas en la producción, reproducción y transformación de las desigualdades que atraviesan a los jóvenes en la actualidad. En específico, busca analizar críticamente el “rol teórico” de la educación como garantía de integración social de las juventudes y como herramienta igualadora; y reflexionar, en clave socio histórica e interseccional acerca de cómo se producen socialmente las juventudes en el marco de las instituciones educativas y desde las regulaciones socioestatales vinculadas a la educación, y a la Educación Sexual Integral (ESI) en particular. ¿Qué tensiones y paradojas se generan al momento de pensar la escuela, la igualdad y la participación de sus miembros? ¿Qué giros epistemológicos es necesario tener en cuenta para poder pensar el protagonismo de las juventudes no en un horizonte futuro, sino en un aquí y ahora? ¿Cómo podemos generar, desde el trabajo con la ESI, un espacio propicio para estos debates?
Cárteles del narcotráfico: poderes permanentes y funciones ocultas
Authors: Cieza Daniel
Published: June 2024

La tesis principal de este artículo es que los llamados cárteles son parte de los poderes permanentes y cumplen varias funciones ocultas.
Homo-Sodoman synty ja huoli miehuudesta
Authors: Nissinen Martti
Published: June 2024

Sodoma-kertomuksesta on aikojen saatossa tullut seksuaali- ja sukupuolivähemmistöjen vastaisen propagandan perusteksti. Polemiikki ei kuitenkaan nouse suoraan Genesiksen luvusta 19 vaan sen pitkästä (homo)seksualisoivasta tulkintahistoriasta. Kertomuksen varhaisimmat tulkinnat kiinnittävät hämmästyttävän vähän huomiota sodomalaisten seksuaaliseen käyttäytymiseen. Pikemminkin heitä moititaan hegemonisen maskuliinisuuden röyhkeimmistä toteuttamistavoista, ylpeydestä ja väkivallasta. Sodoman synti seksualisoituu ensimmäisen kerran Riemuvuosien kirjassa ja samansukupuolinen elementti yhdistyy siihen vasta ensimmäisellä vuosisadalla jKr. Filonin ja Josefuksen kirjoituksissa. Päähuolena näissä tulkinnoissa on maskuliinisuus pikemminkin kuin (homo)seksuaalisuus. Kun näkökulma käännetään homoseksuaalisuudesta miehuuteen, huomio kiinnittyy Sodoma-kertomuksessa ja sen tulkinnoissa tärkeämpiin elementteihin kuin seksiin.
Konkreettisesta toiminnasta abstraktiin ajatteluun
Authors: Mielikäinen Aila
Published: June 2024

Tässä artikkelissa tarkastellaan, miten suomen kielen käsi-sanasta johdettua käsittää-verbiä on käytetty raamatunsuomennoksissa 1500-luvulta 2000-luvulle. Perusaineistona ovat vuoden 1776 Biblian nykyversio (1776/1991) sekä vuosien 1933/1938 ja 1992 käännökset. Vertailussa ovat mukana myös muut vanhan kirjasuomen aikaiset suomennokset (UT 1548, 1642, 1685) ja joitakin 1900–2000-luvun epävirallisia käännöksiä.
Käsittää-verbillä on murteissa ollut konkreettinen merkitys ’saada käsiin, ottaa kiinni, tavoittaa ym.’, mutta sen nykymerkitys on ’ymmärtää, tajuta’. 1500–1700-luvun raamatunsuomennoksissa sanaa on käytetty vanhojen merkitysten mukaisesti, mutta nämä ovat väistyneet kokonaan 1900–2000-luvun suomennoksista ja sanan käyttökontekstit ovat muuttuneet. Joissakin jakeissa käsittää on säilytetty entisissä konteksteissa, eli verbin on tulkittu tarkoittaneen jo vanhoissa käännöksissä ymmärtämistä.
Artikkelissa pohditaan myös käsittää-verbin merkityksenmuutoksen vaiheita ja syitä. Merkityksen abstraktistuminen vastaa muiden eurooppalaisten kielten kehitystä (esim. ruotsin begripa ja saksan begreifen ’tarttua’ > ’ymmärtää’, vrt. latinan comprehendere). Muutos on suomen kielessä selitetty ruotsin kautta saaduksi merkityslainaksi, mutta tämän lisäksi sille on osoitettu murteiden perusteella vahva omakielinen pohja. Sanan abstraktistuminen on tapahtunut kirjakielessä 1800-luvun aikana, jolloin suomesta tuli kaikilla aloilla käytettävä sivistyskieli.
Religio-political and economic backdrops of constitutionalism in Iran in the late 19th and early 20th centuries
Authors:   Universitas Islam Negeri (UIN) Sunan Ampel Surabaya, Indonesia, Fuad Ahmad Nur
Published: June 2024

The article aims to provide a comprehensive analysis of the dynamics that influenced the emergence of constitutionalism and the constitutional revolution in Iran in the late nineteenth and early twentieth centuries. It examines the complex interplay between religious, political and economic factors, elucidating their roles in shaping Iran's constitutional landscape. Through an examination of historical sources and scholarly analysis, the article reveals the significant influence wielded by religious institutions, particularly religious leaders, in either supporting or challenging constitutional reforms. This reflects the complex relationship between traditional religious authority and the emerging demands for secular governance. This article, therefore, explores complicated power struggles among political elites, consisting of a diverse groups of aristocrats, bureaucrats and intellectuals. These factions engaged in intricate maneuvers that often determined the course of constitutionalism in Iran. In addition, the economic backdrop of the late Qajar period, characterized by foreign intervention, economic disparity and social unrest, provided fertile ground for political reform and greater representation. By highlighting the multifaceted interactions between these forces, the article offers valuable insights into the evolution of constitutionalism in Iran. It reveals that understanding these historical dynamics is crucial for comprehending Iran’s contemporary political landscape and the ongoing quest for democratic governance amidst complex religio-political and economic realities.
ARAB ADMINISTRATION AND SETTLEMENT POLICY IN AZERBAIJAN
Authors:   Azerbaijan University, Baku, Azerbaijan, Gurbanov Abbas
Published: June 2024

After the death of the Prophet Muhammad, the caliphs who came to power continued the conquests started with the aim of spreading Islam. Some of these activities were related to Azerbaijan. Like every state, the Arab caliphate had its own administrative system, which was more or less the same in all regions. The Arab armies governed the newly conquered territories by appointing governors. From the first day of its capture, Azerbaijan began to be governed by governors appointed here. The first governor who adopted Ardabil as his center, as it was during the Sassanid period, was Hüzeyfa b. al-Yaman has been. We can say that the Arab caliphate aimed to reduce the influence of the Byzantine and Khazars, the leading states of that time, in the region by attracting the local people to their side and forming a unified power unit relying on the support of the local people in the future struggle against them.
THE FACTOR OF ISLAM RELIGION FOR ENSURING PEACE AMONG CONFESSIONS (USING THE EXAMPLE UZBEKISTAN EXPERIENCE)
Authors:   University of Economics and Pedagogy, Qarshi, Uzbekistan, Murtazova Shahodat
Published: June 2024

This article provide a historical analysis of the factor of Islam in ensuring among confessions, as well as, interreligious peace on the example of the experience of independent Uzbekistan.
ISLAM AND MUSLIMS IN THE ANCIENT PERIOD RUSSIAN LITERATURE
Authors:   Azerbaijan University, Baku, Azerbaijan, Hajili Asif
Published: June 2024

In the article the attitude towards the Islamic religion and Muslims in the ancient Russian literature, first of all the Turks and also the relation to the Islamic religion and Muslim peoples in the literature of the Russian folk art is analyzed. The political, social, spiritual-cultural, literary-philological aspects of the attitude to Islam from ancient times are interpreted. The spread of Islam in Russia by the Khazars, as Turkic community, the positive effect of acquaintance with Islamic culture on Russian culture, relations with the East, statehood, Eastern culture, as well as the Islamic renaissance that began in the 7th-8th centuries AD on Russian culture are explained. In ancient times, the relation to Islam in Russian literature and culture on the formation and essence of philo-orientalism in Russian public opinion in later historical stages is noted. The translation of the Qur'an-i-Karim in Russian literature also has a rich history and the interpretation of this tradition allows us to clarify the historical, political, methodological, philological aspects of the translation of the sacred text and the attitude towards Islam in Russia in general.
On the importance of continuous development in the military domain
Authors: Nordlöf Jonas , Bengtsson Kristofer
Published: June 2024

A significant percentage of modern products and systems purchased from the defense industry are difficult for the buyer to adapt or develop for new needs after lessons learned on the battlefield. This results in the procured systems having unnecessarily short lifespans. This paper contains a literature survey of the implementation and adaptation of military systems, combined with the authors’ own observations from real cases of procurement in the military domain. Furthermore,this paper presents concepts for continuous development in the military domain, addressing several of the issues observed with modern systems. The term “continuous development” is here defined as the continuous modification, improvement and enhancement of military equipment or a military technical system over the course of its life cycle. The paper outlines how compatibility, flexibility and interoperability relate to unmanned aerial vehicles, counter unmanned aerial systems operations and electronic warfare operations, their role in continuous development and why these concepts are important on the modern battlefield. We contend that the ability to modify equipment increases adaptability, and therefore survivability, in conflict scenarios where new threats continuously appear. The paper concludes with recommendations of practical value for the defense industry on how equipment can be adapted to facilitate continuous development.
Cerebral Mucormycosis without Rhino-Orbital Involvement in a Patient with Chronic Kidney Disease
Authors:   Department of Internal Medicine (ID Division), All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India, Das Ananya , P Anantha Krishnan ,   Department of Internal Medicine (ID Division), All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India, Panda Prasan Kumar ,   Department of Internal Medicine (ID Division), All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India, Gupta Avneet Kumar ,   Department of Internal Medicine (ID Division), All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India
Published: June 2024

Isolated cases of cerebral mucormycosis demand high clinical suspicion and prompt diagnosis and treatment. In the present case, the patient was a young diagnosed case of chronic kidney disease (CKD) for two years on maintenance hemodialysis, presented with symptoms of headache and increased intracranial pressure, which necessitated both emergency surgical and medical management and was both diagnosed and managed efficiently. Early recognition of clinical and radiological cues with early institution of a medico-surgical approach, with proper containment of underlying predisposing conditions, is vital for managing mucormycosis. The case elucidates that mucormycosis can present as an isolated cerebral abscess without rhino-orbital involvement. CKD should be considered as a possible immunocompromised state predisposing to mucormycosis.
Assessment of Pulse Oximetry Accuracy in Detecting Hypoxemia in COVID-19 Pneumonia Patients: A Cohort Study
Authors:   Department of General Medicine, All India Institute of Medical Sciences, Mangalagiri, Andhra Pradesh, India, Sridhar Amalakanti , Arepalli Kesava Venkata Raman ,   Department of General Medicine, Great Eastern Medical School and Hospital, Ragolu, Andhra Pradesh, India, Boppana Sri Harsha ,   Department of General Medicine, Great Eastern Medical School and Hospital, Ragolu, Andhra Pradesh, India, Jillella Jyothi Priya ,   Harika College of Physiotherapy, Guntur, Andhra Pradesh, India
Published: June 2024

The accuracy of pulse oximeters in diagnosing hypoxemia, especially in COVID-19 and other viral pneumonia cases, still needs to be determined despite their critical role in monitoring COVID-19 patients. This study aimed to assess the dependability of pulse oximeters in accurately detecting hypoxemia in individuals with COVID-19 pneumonia. A study was undertaken on 40 patients with COVID-19 pneumonia, in which pulse oximeter results were compared to arterial blood gas (ABG) analysis. The results of our study demonstrate a continuous overestimation of 1.77% in pulse oximetry values compared to arterial blood gas (ABG) measurements. When the threshold for SpO2 was set at less than 90%, the sensitivity and specificity were found to be 50% and 76.09%, respectively. These values slightly improved when the threshold was set at less than 92% for SpO2. The findings underscore notable constraints in utilizing pulse oximetry to identify low oxygen levels in COVID-19 pneumonia patients. This emphasizes the importance of interpreting oximeter values cautiously and advocating for more precise techniques, such as arterial blood gas (ABG) measurement, in severe situations.
Extensive Deep Vein Thrombosis: A Rare Manifestation of Disseminated Tuberculosis
Authors:   Department of Gastroenterology, All India Institute of Medical Sciences, New Delhi, India, Swaroop Shekhar , Singla Paras ,   Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India, Baitha Upendra ,   Department of Medicine, All India Institute of Medical Sciences, New Delhi, India, Gupta Gaurav ,   Department of Medicine, All India Institute of Medical Sciences, New Delhi, India, Singh Amandeep ,   Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
Published: June 2024

A 20-Year-Old Male With Disseminated Tuberculosis (Pulmonary, Pleural, And Lymph Node TB) Presented With Unusual Manifestation In The Form Of Extensive Deep Vein Thrombosis (DVT) Involving Bilateral Popliteal Veins, Femoral Veins, Iliac Veins, And Infra-Hepatic Inferior Vena Cava (IVC). Upon Follow-Up With The Patient After Two Months Of Therapy, There Was A Significant Clinical Improvement, And Edema And Tenderness Of The Lower Limb Had Decreased.
Konuşma Eğitimi Sürecinde Geri Bildirim Kaynakları
Authors: Elçi Zeynal Abidin
Published: June 2024

Bu çalışmanın amacı, öğrencilerin sözlü metin üretiminin her aşamasını verimli geçirmesinde öğretmen, akran ve öz değerlendirmeye dayalı geri bildirimin rolünü araştırmaktır. Bu amaçla, metin üreticisinin geri bildirim kaynaklarından (öğretmen, akran, öğrencinin kendisi) aldığı geri bildirimlerin metin üretim sürecine etkisini araştırmaya yönelik çalışmalar incelenmiştir. Çalışmada, sözlü metinleri ölçme-değerlendirmede geri bildirim kaynakları üzerinde durulmuş, sözlü metin ile yazılı metnin anlatım özellikleri, paylaşım süreci, iki metin yapısının benzer ve farklı yönleri alan yazındaki bilgiler ışığında tartışılmıştır. Sözlü metin üretim sürecinin aşamaları, her aşamayı oluşturan bileşenlerin taşıması gereken nitelikler açıklanmıştır. Geri bildirim kaynaklarının sözlü metin üretim sürecini ne yönde etkilediğinin incelenmesi amacıyla alan yazın taraması türlerinden biri olan geleneksel alan yazın taraması yapılmıştır. Bu yöntemle üç geribildirim türüne ilişkin çalışmalar incelenerek bir karşılaştırmaya gidilmiştir. Alan yazında taranan çalışmalardan öğretmen, akran ve öz değerlendirmeye dayalı geri bildirimin öğrencilerin metin üretimlerini olumlu yönde etkilediği, öğrencilerin bağımsız sözlü metin üreticisi olmalarını desteklediği sonucuna ulaşılmıştır. Ayrıca geri bildirim kaynaklarının etkili olması için taşıması gereken niteliklerin, verilme biçiminin ve zamanının önemli olduğu sonucuna varılmıştır.
AI Ethics
Authors:   Africa Institute For Regulatory Affairs LBG, Mensah George Benneh
Published: June 2024

This paper explores the ethical considerations of AI, focusing on bias mitigation, transparency, and accountability. Employing the CREAC framework, the study examines the context of AI ethics, the rules and guidelines proposed for responsible AI, the consequences of failing to address ethical considerations, and an analysis of case studies and research findings. The paper concludes with recommendations for ethical AI development and deployment, including prioritizing bias mitigation, enhancing transparency and explainability, establishing clear accountability mechanisms, fostering interdisciplinary collaboration, investing in public education and engagement, and continuously monitoring and adapting AI systems. The analysis contributes to the growing body of knowledge on AI ethics by providing a comprehensive and interdisciplinary approach, drawing on insights from computer science, ethics, law, and social sciences. The paper's practical significance lies in its actionable recommendations, which offer a roadmap for stakeholders seeking to address the ethical challenges posed by AI and ensure responsible AI development and deployment.
Implementasi Algoritma Redundant Pattern Encoding Untuk Menyisipkan Pesan Teks Ke Dalam Gambar dan Algoritma Fibonacci Codes Untuk Kompresi
Authors: Aditiya Frayogi
Published: June 2024

Information is a collection of data in the form of unified text that is public or confidential. Confidential data is data that contains something or that is not for publication. One way to secure the data is to use Steganography techniques. This provides tremendous benefits for maintaining data confidentiality. In steganography there are several methods, one of which is Redundant Pattern Encoding. However, from this process, the object that will be used as a container to accommodate the data will experience a change in the size of the data. This can raise the suspicion of many parties who want to access the data. This study describes how the procedure is carried out to compress objects that are used as containers to insert messages. The process uses the Fibonacci Codes method which is a simple and very simple data compression method. The results of this research will produce a stronger level of data security.
Sistem Pakar Diagnosa Paget's Disease dengan Menerapkan Algoritma Teorema Bayes
Authors: Saragih Rico Albert , Marbun Desika , Mesran Mesran
Published: June 2024

Paget's Disease, also known as Paget's Disease of the bone, is a bone disorder that typically arises in the elderly, particularly after the age of 40. The risk of this disease increases with advancing age. Aging and genetic factors are believed to play a role in the development of this condition. Symptoms include bone pain, bone fragility, abnormal bone growth, changes in bone shape, decreased hearing, as well as symptoms such as headaches, dizziness, and joint complaints. Expert systems or artificial intelligence draw inspiration from the knowledge of experts to analyze situations. With algorithms like the Bayes theorem, this system provides solutions to emerging issues. In this context, expert systems aid doctors in identifying diseases without face-to-face consultations. The Bayes theorem serves as the foundation for this mechanism, emulating expert abilities. This research applies the Bayes theorem for an efficient and objective diagnosis of Paget's Disease. The results indicate a strong likelihood of patients having Paget's Disease at 73.87%. Consequently, the use of expert systems has the potential to enhance efficiency and objectivity in handling cases, assisting doctors in formulating diagnoses based on presenting symptoms.
Sistem Pendukung Keputusan Rekomendasi Hotel Bintang Tiga Menggunakan Kombinasi Entropy dan Combine Compromise Solution
Authors: Wahyudi Agung Deni , Sumanto Sumanto , Setiawansyah Setiawansyah , Yudhistira Aditia
Published: June 2024

Three Star Hotels are lodging places that offer the perfect balance between comfort, adequate facilities, and affordable prices. With a friendly atmosphere and professional service, the hotel welcomes guests from various backgrounds warmly. One of the problems in choosing a Three Star Hotel is confusion due to variations in quality and facilities among hotels that have similar ratings. Although they share the same categories, the standards and services offered can vary greatly. This can make potential guests find it difficult to choose the right hotel that suits their preferences and needs. In addition, some hotels may not meet guest expectations due to issues such as poor cleanliness or facilities that do not function properly, which can generate dissatisfaction. The combination of Entropy weighting and the Combine Compromise Solution method can be a powerful approach in providing three-star hotel recommendations to potential guests. By combining these two methods, it can produce more informed and objective three-star hotel recommendations. Entropy weighting helps in assessing the relative importance of each criterion, while the Combine Compromise Solution allows us to reach a compromise solution that blends different preferences and criteria. The result is recommendations that are more accurate and tailored to potential guests' needs and preferences. The recommendation results showed that AN Hotel with a value of 1,782 got 1st place, AL Hotel with 1.271 got 2nd place, and YN Hotel with 1,145 got 3rd rank.
Mengoptimalkan Motivasi Belajar: Pengaruh Signifikan Kualitas Pendidikan dan Kepuasan Mahasiswa
Authors: Bakti Ferry , Dendi Agus , Amir Ari , Isnanto Burham
Published: June 2024

The quality of education is a major concern in academia and is often associated with student satisfaction and learning motivation. This study aims to analyze the effect of teaching quality, educational facilities, and administrative services on student satisfaction, as well as the impact on learning motivation in the context of higher education in Indonesia. Using the survey method, data was collected from 160 students at the ISB Atmaluhur Pangkalpinang campus. Data analysis was performed using structural equation modeling (SEM) and SPSS to test the research hypothesis. The results showed that the quality of teaching, educational facilities, and administrative services had a positive and significant effect on student satisfaction, both partially and simultaneously. In addition, student satisfaction also has a positive and significant effect on learning motivation. These findings broaden understanding of the factors that influence student satisfaction and learning motivation, and emphasize the importance of a holistic approach in improving the quality of higher education. The practical implications of this research include the need for higher education institutions to focus on improving the quality of teaching, providing adequate educational facilities, and improving the quality of administrative services to achieve optimal student satisfaction and encourage higher learning motivation.
Разработка информационной системы по фитосанитарным требованиям стран – импортеров российской зерновой продукции
Authors: Гребенников К.А. , Касаткин Д.Г. , Ловцова Ю.А. , Шнейдер Ю.А.
Published: June 2024

В статье представлены результаты разработки электронного справочника (информационной системы) по фитосанитарным требованиям стран – импортеров российской зерновой продукции. Изложены методы, основные этапы и особенности полученных результатов. Дана оценка практической значимости и перспектив дальнейшего пополнения и развития информационной системы.
Sistemas de administração da produção e tecnologias apropriadas: agroecologia e sustentabilidade socioambiental
Authors: Novaes Souza Maurício , de Paula Dias Mendonça Rodrigo Leonardo , Rezende Bighi Adriana , Cunha Lopes Alessandra , Alves de Novaes Gabriela , Alves de Novaes Clarissa
Published: June 2024

Gabriela Alves de Novaes, Clarissa Alves de Novaes
THOUGHTS OF MAMED AMIN RASULZADE ABOUT THE ATTITUDE OF THE NİZAMİ GANJAVİ TO LIFE, PEOPLE AND WOMEN
Authors:   Azərbaycan Respublikasının Təhsil İnstitutu, Amiraliyeva Irada
Published: June 2024

Nizami Ganjavi wrote his works in Persian. For this reason, Iran claims that he is a Persian poet. However, Nizami was born in Ganja and was buried in Ganja. Mammad Amin Rasulzade proved that Nizami Ganjavi is an Azerbaijani and an Azerbaijani poet by writing the work ―The Great Azerbaijani Poet Nizami‖ in the 40s of the 20th century. This article focuses on the opinion of Mammad Amin Rasulzadeh about Nizami Ganjavi’s attitude to life, man and woman.
HEYDAR ALIYEV AND THE AZERBAIJANI LANGUAGE
Authors: Ismayilova Khurshud
Published: June 2024

The mother tongue of every nation is the most important indicator of its existence, self-affirmation. The mother tongue is an irreplaceable national treasure that carries the uniqueness of the people, the nation, its historical background and culture, its rich vocabulary, beliefs and traditions, moral behavior and outlook, and transmits it from century to century. As Heydar Aliyev, the national leader of the Azerbaijani people, wisely said, "what makes a people a nation, what makes a nation a nation is its mother tongue." The Azerbaijani language, the state language of the Republic of Azerbaijan, currently has a unique place among world languages, as they say, a signature among signatures. In the words of the President of the Republic of Azerbaijan Mr. Ilham Aliyev, "Our mother tongue is characterized by the richness of its possibilities, the fluency of the sound structure and the stability of the grammatical structure".
MAIN DIRECTIONS OF INDEPENDENT ACTIVITY OF STUDENTS – DEVELOPMENT OF SELF-EDUCATION
Authors: Suleymanov Mubariz
Published: June 2024

One of the main directions of the reform in education in modern times is aimed at the development of students' independent activity and self-education. Self-study method has a special role in developing students' ability to learn to learn. The main essence of the self-education method is that training is not only about enriching the memory of students with new scientific knowledge (information), but also about the independent acquisition and assimilation of more knowledge, the acquisition of the most important skills and talents, personal qualities and abilities, based on the regular development of thinking. creates conditions.
ANALYSIS OF RESULTS ON SCIENTIFIC LITERACY COMPETENCE OF AZERBAIJAN STUDENTS IN PISA 2022 RESEARCH STUDY
Authors: Aghacanli Ali
Published: June 2024

What scientific literacy competency means for PİSA studies is outlined briefly in the article. A study was conducted to determine the types of questions that students find challenging to answer and the skills necessary to answer these kinds of questions through analyzing the average indicators of scientific literacy of our students. Ultimately, suggestions were put forward with the aim of boosting PİSA 2025 outcomes.
WINNING PEOPLE, WINNING LEADER
Authors: Abbasov Akif
Published: June 2024

In this article, written on the occasion of his great victory in the presidential elections, readers are introduced to the achievements and valuable ideas of Mr. Ilham Aliyev. First of all, some points from the interview of the President of the Republic of Azerbaijan to local TV channels on January 10, 2024; later, the statements he made at the swearing-in ceremony in the Milli Majlis on February 14, 2024 are recalled. It is considered appropriate that the younger generation can benefit from these ideas.
Unleashing geological sequestration potential of mature oilfield by enforcing 4-dimensional seismic model-based inversion in Widuri Field, Indonesia
Authors:   Pertamina Hulu Energi OSES, RDTX Square Jl. Prof. Dr. Satrio No. 164, Setiabudi, South Jakarta 12930, Indonesia, Ralanarko Dwandari , Pangestu Brimas Aptanindia ,   Pertamina Hulu Energi OSES, RDTX Square Jl. Prof. Dr. Satrio No. 164, Setiabudi, South Jakarta 12930, Indonesia, Sunardi Edy ,   Faculty of Geological Engineering, Universitas Padjadjaran, Deanery Building Jl. Ir. Soekarno, Km. 21 Jatinangor, West Java 45363, Indonesia, Syafri Ildrem ,   Faculty of Geological Engineering, Universitas Padjadjaran, Deanery Building Jl. Ir. Soekarno, Km. 21 Jatinangor, West Java 45363, Indonesia, Adhiperdana Billy Gumilar ,   Faculty of Geological Engineering, Universitas Padjadjaran, Deanery Building Jl. Ir. Soekarno, Km. 21 Jatinangor, West Java 45363, Indonesia
Published: June 2024

Implementing reservoir characterization by undertaking seismic inversion on time-lapse surveys is very effective for observing the distribution and changes in the hydrocarbon reservoir. In mature oilfields, these changes are most likely influenced by the thermodynamic activities including the injection of fluid into the reservoir, which can change the volume, pressure, and composition of the geological formations. Fluid injection (in this case, water injection) into the reservoir is typically used as an oil and gas booster to increase production through EOR (Enhanced Oil Recovery). However, in light of CCUS (Carbon Capture Utilization and Storage) application, injecting CO2 can be considered as a new EOR strategy development, with the dual objectives of increasing oil and gas production as well as lowering carbon emissions at the same time. The 4-dimensional (4D) seismic data available over Widuri Field covers an area of 125 km2, with 884 inlines and 905 crosslines, acquired in 1991 and 2004 over the same area. The inversion algorithm is using seismic deconvolution to generate an acoustic impedance model before developing a geological reservoir model. Reservoir characterization was conducted in this study to obtain detailed information of the reservoir zones by determining the impact of water injection that replaces hydrocarbons. Intervals and areas with an abundance of water can be considered as potential CO2 sequestration in the future, as a part of the CCUS application. In conclusion, the findings of increasing impedance from inversion data from 1991 to 2004 can indicate the presence of existing porosity and permeability. This evidence could indicate reservoir capability as CO2 storage.
New technologies for seismic resolution enhancement and bandwidth expansion: Applications in SE Asian Basin
Authors:   Department of Geophysical Engineering, Faculty of Mines, Istanbul Technical University, 34467 Istanbul, Turkiye, Bashir Yasir , Abdul Latiff Abdul Halim ,   Centre for Subsurface Imaging (CSI), Universiti Teknologi PETRONAS, 32610 Seri Iskandar, Perak, Malaysia, Sajid Muhammad ,   PETRONAS Research Sdn. Bhd., Lot 3288 & 3289, Off Jln Ayer Itam, Kawasan Institusi Bangi, 43000 Kajang, Selangor, Malaysia
Published: June 2024

Over the last few years, the petroleum giant and its partner have effectively implemented new marine seismic technologies in this part of the world. During the acquisition phase, the industry has observed the introduction of novel broadband acquisition techniques such as dual-sensor cable, multiple towed streamers (over/under), slanted and variable depth streamers, and isometric areal recording. The application of these techniques has resulted in a noteworthy enhancement of the recorded data’s bandwidth. The focus of this paper is on the improvement of seismic bandwidth expansion resulting from advancements in marine broadband acquisition, innovative processing techniques, and inversion methodology. The outcome leads to a noteworthy enhancement in the vertical resolution, which proves to be valuable in the identification of thin stacked pay beds and the creation of a reservoir model that is constrained by seismic data. This paper focuses on the imaging aspect, particularly the complex structures. The utilization of wide and full azimuth (Circular) recording and the resolution of Gas wipeout issues through seabed acquisition with Ocean Bottom Cables (OBC) have been advantageous. By utilizing de-ghosted or far-field signature modeled techniques on the processing side, it is possible to increase the bandwidth for both legacy and modern high-quality data, such as Q-marine. A novel de-convolution technique has been developed, which can enhance signal frequency to a considerable extent while minimizing or eliminating any impact on noise. The article presents various wavelet transform techniques that can effectively enhance the signal-to-noise ratio (S/N). The methods are noteworthy due to their ability to be swiftly executed post-stack while incurring minimal expenses. Further, the inversion techniques, with a focus on stochastic elastic inversion, generates broadband data, enabling the identification of pay sand that falls below the quarter of wavelength criteria. The developed techniques are novel and have been validated using authentic Offshore Malaysia data.
Una mirada crítica y diferente de la salud de la mujer
Authors: Zaballa i Madrid Esther
Published: June 2024

Las mujeres han sido invisibles en la medicina, puesto que han estado ausentes del objeto de la investigación biomédica hasta el siglo XX. Hasta la última década del siglo XX, la salud de la mujer se había estudiado y evaluado solo en relación con la salud reproductiva y en torno al embarazo y al parto. No fue hasta los años noventa cuando se empezó a incluir a la mujer en algunos estudios científicos, pero sin considerar sus condiciones de vida y trabajo y su carga psicosocial, claves en la salud. Es importante destacar que las mujeres son bioacumuladores de sustancias tóxicas que afectan a su salud, la de sus descendientes y la de los hijos de estos, tres generaciones en total.
Desigualdad y sistema de educación: propuestas para compensar la desigualdad
Authors: López Domínguez Laura
Published: June 2024

El sistema de educación español, como el de otros países, separa el alumnado en dos tipos de escuelas: las públicas y las privadas (concertadas o no). A las escuelas privadas acceden, mayoritariamente, los descendientes de las familias con más recursos. Este artículo explica cómo este sistema dual es generador y reproductor de desigualdades; valora las posibilidades de sustituir este modelo por uno completamente público; y discute propuestas alternativas: modificaciones fiscales, el cheque escolar y la introducción de medidas de discriminación positiva como método de compensación social, en forma de reserva de plazas de trabajo en las empresas privadas y en las administraciones públicas para las personas formadas en instituciones públicas.
Las dimensiones del bienestar personal: un enfoque integral
Authors: Segura Virella Gemma
Published: June 2024

A partir de lo que aporta la psicología positiva, la autora considera que el bienestar personal es una combinación entre el cultivo positivo y responsable de los propios pensamientos, emociones y acciones, de las relaciones que mantenemos con las otras personas y el sentido que le damos a nuestra propia existencia. El artículo proporciona la comprensión de todos estos ámbitos y cómo contribuyen al estado general de bienestar personal, desde el convencimiento de que la responsabilidad de este bienestar es una decisión personal y nos corresponde a cada uno de nosotros darnos cuenta de su importancia.
Editorial: Una visión holística del bienestar: soberanía personal, estado y sostenibilidad
Authors: Álvarez Fernando
Published: June 2024

Os damos la bienvenida a un nuevo número de la revista Oikonomics, en esta ocasión, dedicado al concepto de bienestar. En las páginas que siguen, nos embarcamos en un viaje a través de las múltiples facetas del bienestar, explorando cómo aspectos individuales y colectivos se entrelazan para crear una vida plena y satisfactoria. El bienestar es un concepto amplio que abarca diversos aspectos de la vida de una persona; pero al mismo tiempo es un proceso continuo de autodescubrimiento y autorrealización que implica cuidar y nutrir tanto el cuerpo como la mente, fomentar relaciones saludables y contribuir al bienestar de los demás y del entorno en general.
Promoviendo el bienestar a través de la vida en comunidad: el ‘cohousing’ como ejemplo
Authors: Álvarez Fernando
Published: June 2024

En la búsqueda constante de una vida más plena y satisfactoria, el ser humano ha descubierto que uno de los caminos más efectivos es a través de la vida en comunidad. La vida en comunidad es mucho más que simplemente habitar un mismo espacio físico. Implica un compromiso compartido hacia el bienestar colectivo, donde cada individuo encuentra no solo apoyo emocional, sino también oportunidades para crecer y desarrollarse plenamente. En este artículo exploraremos cómo la interacción social, la colaboración y el sentido de pertenencia a un grupo pueden influir de manera significativa en nuestra calidad de vida y felicidad, centrando nuestra atención en un modelo particular: el cohousing.
La sostenibilidad del sistema de pensiones en España
Authors: Llobet Dalmases Joan
Published: June 2024

Este documento analiza la sostenibilidad del sistema de pensiones en España en el marco del estado del bienestar. Se destaca que las pensiones son fundamentales para proporcionar seguridad económica y reducir la pobreza entre la población jubilada. A pesar de esto, se alerta sobre la carencia de recursos para afrontar las obligaciones de pensiones a largo plazo, con el envejecimiento de la población y otros factores demográficos como desafíos principales. Se subraya que las tensiones financieras del sistema de pensiones español son evidentes, con un aumento constante de personas jubiladas y del gasto en pensiones a lo largo del tiempo, mientras que las afiliaciones a la Seguridad Social tienen un comportamiento más volátil.
Physiological roles of endocytosis and presynaptic scaffold in vesicle replenishment at fast and slow central synapses
Authors: Mahapatra Satyajit , Takahashi Tomoyuki
Published: June 2024

After exocytosis, release sites are cleared of vesicular residues to replenish with transmitter-filled vesicles. Endocytic and scaffold proteins are thought to underlie this site-clearance mechanism. However, the physiological significance of this mechanism at diverse mammalian central synapses remains unknown. Here, we tested this in a physiologically optimized condition using action potential evoked EPSCs at fast calyx synapse and relatively slow hippocampal CA1 synapse, in post-hearing mice brain slices at 37°C and in 1.3 mM [Ca2+]. Pharmacological block of endocytosis enhanced synaptic depression at the calyx synapse, whereas it attenuated synaptic facilitation at the hippocampal synapse. Block of scaffold protein activity likewise enhanced synaptic depression at the calyx but had no effect at the hippocampal synapse. At the fast calyx synapse, block of endocytosis or scaffold protein activity significantly enhanced synaptic depression as early as 10 ms after the stimulation onset. Unlike previous reports, neither endocytic blockers nor scaffold protein inhibitors prolonged the recovery from short-term depression. We conclude that the release-site clearance by endocytosis can be a universal phenomenon supporting vesicle replenishment at both fast and slow synapses, whereas the presynaptic scaffold mechanism likely plays a specialized role in vesicle replenishment predominantly at fast synapses.
Maternal smoking DNA methylation risk score associated with health outcomes in offspring of European and South Asian ancestry
Authors: Deng Wei Q. , Cawte Nathan , Campbell Natalie , Azab Sandi M. , de Souza Russell J , Lamri Amel , Morrison Katherine M. , Atkinson Stephanie A. , Subbarao Padmaja , Turvey Stuart E. , Moraes Theo J. , Teo Koon K. , Mandhane Piush , Azad Meghan B. , Simons Elinor , Pare Guillaume , Anand Sonia S.
Published: June 2024

Maternal smoking has been linked to adverse health outcomes in newborns but the extent to which it impacts newborn health has not been quantified through an aggregated cord blood DNA methylation (DNAm) score. Here we examine the feasibility of using cord blood DNAm scores leveraging large external studies as discovery samples to capture the epigenetic signature of maternal smoking and its influence on newborns in White European and South Asian populations. We first examined association between individual CpGs and cigarette smoking during pregnancy, smoking exposure in two White European birth cohorts (n = 744). Several previously reported genes for maternal smoking were supported, with the strongest and most consistent signal from the
GFI1
gene (6 CpGs with
p
< 5×10
-5
). Leveraging established CpGs for maternal smoking, we constructed a cord blood epigenetic score of maternal smoking that was internally validated in one of the European-origin cohorts (n = 347). This score was then tested for association with smoking status, secondary smoking exposure during pregnancy, and health outcomes in offspring measured after birth in an independent white European (n = 397) and a South Asian birth cohort (n = 504). The epigenetic maternal smoking score was strongly associated with smoking status during pregnancy (OR=1.09 [1.07,1.10],
p
=1.96×10
-32
) and more hours of self-reported smoking exposure per week (1.97 [1.22, 2.71],
p
=2.80×10
-7
) in White Europeans, but not with self-reported exposure (
p
> 0.05) in South Asians. The same score was consistently associated with smaller birth size (-0.22 cm [-0.35, -0.083],
p
=0.0016) and lower birth weight (-0.05kg [-0.075, -0.025],
p
=3.42×10
-4
) in the combined South Asian and White European cohorts. This cord blood epigenetic score can help identify babies exposed to maternal smoking and assess its long-term impact on growth. Notably, these results indicate a consistent association between the DNAm signature of maternal smoking and a small body size and low birthweight in newborns, in both white European mothers who exhibited some amount of smoking and in South Asian mothers who themselves were not active smokers.
Mechanism of Dimer Selectivity and Binding Cooperativity of BRAF Inhibitors
Authors: Clayton Joseph , Romany Aarion , Matenoglou Evangelia , Gavathiotis Evripidis , Poulikakos Poulikos I. , Shen Jana
Published: June 2024

Aberrant signaling of BRAF
V600E
is a major cancer driver. Current FDA-approved RAF inhibitors selectively inhibit the monomeric BRAF
V600E
and suffer from tumor resistance. Recently, dimer-selective and equipotent RAF inhibitors have been developed; however, the mechanism of dimer selectivity is poorly understood. Here, we report extensive molecular dynamics (MD) simulations of the monomeric and dimeric BRAF
V600E
in the apo form or in complex with one or two dimer-selective (PHI1) or equipotent (LY3009120) inhibitor(s). The simulations uncovered the unprecedented details of the remarkable allostery in BRAF
V600E
dimerization and inhibitor binding. Specifically, dimerization retrains and shifts the
α
C helix inward and increases the flexibility of the DFG motif; dimer compatibility is due to the promotion of the
α
C-in conformation, which is stabilized by a hydrogen bond formation between the inhibitor and the
α
C Glu501. A more stable hydrogen bond further restrains and shifts the
α
C helix inward, which incurs a larger entropic penalty that disfavors monomer binding. This mechanism led us to propose an empirical way based on the co-crystal structure to assess the dimer selectivity of a BRAF
V600E
inhibitor. Simulations also revealed that the positive cooperativity of PHI1 is due to its ability to preorganize the
α
C and DFG conformation in the opposite protomer, priming it for binding the second inhibitor. The atomically detailed view of the interplay between BRAF dimerization and inhibitor allostery as well as cooperativity has implications for understanding kinase signaling and contributes to the design of protomer selective RAF inhibitors.
In vivo targeted and deterministic single cell malignant transformation
Authors: Scerbo Pierluigi , Tisserand Benjamin , Delagrange Marine , Debare Héloïse , Bensimon David , Ducos Bertrand
Published: June 2024

Why does a normal cell possibly harboring genetic mutations in oncogene or tumor suppressor genes becomes malignant and develop a tumor is a subject of intense debate. Various theories have been proposed but their experimental test has been hampered by the unpredictable and improbable malignant transformation of single cells. Here using an optogenetic approach we permanently turn on an oncogene (KRASG12V) in a single cell of a zebrafish brain that, only in synergy with the transient co-activation of a reprogramming factor (VENTX/NANOG/OCT4), undergoes a deterministic malignant transition and robustly and reproducibly develops within 6 days into a full-blown tumor. The controlled way in which a single cell can thus be manipulated to give rise to cancer lends support to the “ground state theory of cancer initiation” through “short-range dispersal” of the first malignant cells preceding tumor growth.
Bidirectional dysregulation of synaptic glutamate signaling after transient metabolic failure
Authors: Passlick Stefan , Ullah Ghanim , Henneberger Christian
Published: June 2024

Ischemia leads to a severe dysregulation of glutamate homeostasis and excitotoxic cell damage in the brain. Shorter episodes of energy depletion, for instance during peri-infarct depolarizations, can also acutely perturb glutamate signaling. It is less clear if such episodes of metabolic failure also have persistent effects on glutamate signaling and how the relevant mechanisms such as glutamate release and uptake are differentially affected. We modelled acute and transient metabolic failure by using a chemical ischemia protocol and analyzed its effect on glutamatergic synaptic transmission and extracellular glutamate signals by electrophysiology and multiphoton imaging, respectively, in the hippocampus. Our experiments uncover a duration-dependent bidirectional dysregulation of glutamate signaling. Whereas short chemical ischemia induces a lasting potentiation of presynaptic glutamate release and synaptic transmission, longer episodes result in a persistent postsynaptic failure of synaptic transmission. We also observed an unexpected hierarchy of vulnerability of the involved mechanisms and cell types. Axonal action potential firing and glutamate uptake were unexpectedly resilient compared to postsynaptic cells, which overall were most vulnerable to acute and transient metabolic stress. We conclude that even short perturbations of energy supply lead to a lasting potentiation of synaptic glutamate release, which may increase glutamate excitotoxicity well beyond the metabolic incident.
Facial expression recognition (FER) survey: a vision, architectural elements, and future directions
Authors: Ullah Sana , Ou Jie , Xie Yuanlun , Tian Wenhong
Published: June 2024

With the cutting-edge advancements in computer vision, facial expression recognition (FER) is an active research area due to its broad practical applications. It has been utilized in various fields, including education, advertising and marketing, entertainment and gaming, health, and transportation. The facial expression recognition-based systems are rapidly evolving due to new challenges, and significant research studies have been conducted on both basic and compound facial expressions of emotions; however, measuring emotions is challenging. Fueled by the recent advancements and challenges to the FER systems, in this article, we have discussed the basics of FER and architectural elements, FER applications and use-cases, FER-based global leading companies, interconnection between FER, Internet of Things (IoT) and Cloud computing, summarize open challenges in-depth to FER technologies, and future directions through utilizing Preferred Reporting Items for Systematic reviews and Meta Analyses Method (PRISMA). In the end, the conclusion and future thoughts are discussed. By overcoming the identified challenges and future directions in this research study, researchers will revolutionize the discipline of facial expression recognition in the future.