bluuebunny/crossref_metadata_2025 huggingface dataset:
Association of helicobacter pylori infection with coronary artery disease and the severity of angiographic lesions
Authors: Sensoy Nur Ozer , Unverdi Selman
Published: February 2025

Objective: There are controversies evaluating the association between different strains of Helicobacter pylori (HP) and occurrence of coronary arterial disease (CAD). HP may facilitate gastric ulcers and gastrointestinal bleeding. As angiographic lesions of high thrombus burden needs more potent and risky antithrombotic treatment regimens, we aimed to investigate the role of different strains of HP for angiographic lesions with high thrombus burden.
Methods: Medical and drug history of 109 consecutive patients who were candidate for coronary angiography were taken. Blood samples were obtained to measure anti HP (Ig) immunoglobulin G and anti-CagA (cytotoxin-associated gene) IgG antibody. According to angiography reports, participants were divided into three groups. Normal (n = 34), lesions with no thrombus (n=38) and lesions with thrombus (n = 37). To measure the association between CagA positive and less virulan strains of HP with the severity of CAD, ordinal logistic regression tests were used by adjusting age, sex, history of hypertention, diabetes mellitus , dyslipidemia and smoking.
Results: The mean ages of patients with and without CAD were 59±14. The prevalence of seropositivity to HP IgG titer was 69% (n=75). Fifty nine (79%) subject had CagA IgG seropositivity. Positive CagA IgG serology was 67% (n=50) and 44% (n=15) in CAD and control groups respectively. While HP IgG serology wasn’t associated with lesion severity; CagA IgG serology was independently associated with lesion severity (OR: 2.4 (1.1-5.6) p=0.03).
Conclusion: Colonization of CagA positive HP was an independent risk factor for angiographic lesion severity..
Extraspinal incidental findings on cervical vertebrae magnetic resonance imaging
Authors: Tonkaz Gökhan , İbiş Esra , Erkal Duygu , Tonkaz Mehmet , Bekci Tümay
Published: February 2025

Objective: Cervical magnetic resonance (MR) imaging is routinely employed for the assessment of cervical disc pathologies, the evaluation of the cervical spinal canal, and the detection of spinal lesions. The aim of this study was to determine the prevalence of extraspinal incidental findings in patients undergoing cervical MR imaging and to assess the reporting rates of these findings in archived radiologic reports.

Methods: A retrospective review was conducted of digital patient archives between January 2022 and December 2023, comprising 1,000 patients who underwent cervical MR imaging at our institution. Two radiologists jointly identified extraspinal incidental findings. This descriptive study analyzed images obtained using a 1.5 Tesla MR imaging system with standard neck coils, evaluating the prevalence and reporting frequency of incidental findings.

Results: Among 1,000 patients (580 males, 420 females, mean age: 49±31 years), extraspinal incidental findings were observed in 66.4% (n=664) of cases. The most frequent findings were thyroid nodules (13.8%, n=138), goiter (12.2%, n=122), and mucosal thickening of the paranasal sinuses (11.5%, n=115). Incidental findings were more prevalent in women and in the middle-aged group (35-59 years). Only 14.6% of the 664 incidental lesions were documented in radiology reports. These lesions exhibited variability in anatomical location.

Conclusions: This study demonstrates that extraspinal incidental findings are common in routine cervical MR imaging but are often overlooked in radiological reports. Given the potential clinical significance of these findings, their inclusion in reports is important for patient care and management.
Histopathological comparison of incision methods in transconjunctival blepharoplasty: a rat model study
Authors: Selamioğlu Engin , Altundağ İlker , Ocak Mustafa Sertaç , Göztepe Mehmet Berke , Demir Ahmet
Published: February 2025

Objective: The choice of incision method is critical in transconjunctival blepharoplasty, affecting both the wound healing process and aesthetic outcomes. This study aimed to compare the histopathological effects of four different incision methods: scalpel, electrocautery, radiocautery, and laser, on wound healing in an animal model.

Methods: A total of 54 female Sprague-Dawley rats were divided into nine groups, each subjected to different incision methods on their palpebral conjunctiva. Specimens were collected immediately after the incision and at 1- and 2-week intervals to evaluate wound width, depth, vascular proliferation, inflammation, and fibrosis.

Results: Analysis revealed that scalpel and laser incisions resulted in narrower and shallower defects immediately post-operation, while electrocautery and radiocautery produced the most pronounced tissue trauma. By the first week, electrocautery showed the least vascular proliferation, inflammation, and fibrosis, while radiocautery exhibited the most pronounced effects. At the second week, scalpel incisions showed the least inflammation and vascular proliferation, while fibrosis was least observed in radiocautery incisions. Interestingly, despite the initial trauma caused by electrocautery, this method showed less fibrosis over time, suggesting reduced long-term scarring compared to radiocautery. Laser incisions also showed favorable healing outcomes, but with more moderate results compared to the scalpel group. Overall, the study highlights the varying impacts of each incision method on the healing process, indicating that scalpel and laser offer advantages in the early stages of healing, while electrocautery, despite initial trauma, may result in less long-term scarring.

Conclusion: The results highlight the importance of selecting the appropriate incision method to minimize complications and optimize healing in transconjunctival blepharoplasty.
Uso de anestesia em pacientes com comorbidades: Abordagem em pacientes com doenças Cardiovasculares, Hepáticas e Renais
Authors: Diógenes Kayky Eduardo Perdiz , Lopes Vitor Velloso , Oliveira Tássyo Alax Nascimento Sampaio de , Picanço Yasmin Minatovicz Ferreira , Cunha Melissa Gabriela Bitar , Oliveira Carlos Roberto de , Marques Matheus Augusto Masullo , Castro Lorena Karen de Morais Moura , Abreu Abraão Gomes , Assad Michele Maia , Moreira Erica Cristina , Matos Luana Oliveira Seixas , Azeredo Isabela Bedim Simas de Oliveira , Fernandes Kauane Kelly Wentz , Guimas Lucas Matheus Fadoul
Published: February 2025

O uso de anestesia em pacientes com comorbidades, especialmente aqueles com doenças cardiovasculares, hepáticas e renais, exige uma abordagem cuidadosa e individualizada. Essas condições podem alterar a farmacocinética e a farmacodinâmica dos agentes anestésicos, além de aumentar os riscos de complicações perioperatórias. O objetivo deste estudo é analisar as considerações e estratégias anestésicas em pacientes com essas comorbidades, buscando otimização dos cuidados durante o processo cirúrgico. Para a coleta de dados, foram revisados ​​artigos e diretrizes clínicas em fontes como PubMed, SciELO e literatura especializada. Pacientes com doenças cardiovasculares podem apresentar risco de instabilidade hemodinâmica, exigindo monitoramento rigoroso e, muitas vezes, uma escolha de anestésicos que não prejudicam a função cardíaca. Em pacientes hepáticos, a função reduzida do fígado pode afetar a metabolização dos medicamentos, exigindo ajustes nas dosagens. Já em pacientes renais, o uso de certos anestésicos pode resultar em acúmulo de metabólitos, o que pode aumentar o risco de toxicidade. Dessa forma, as abordagens anestésicas para pacientes com comorbidades exigem uma análise detalhada das condições do paciente e uma escolha de cuidados com os medicamentos e técnicas, visando minimizar o risco.
Fisiopatologia da COVID-19 e as suas complicações persistentes
Authors: Coutinho de Araujo Marcos Vinicius , Sousa Leticia de Fatima Oliveira de , Rocha Ana Gabriela Batista da , Silveira Gisele Meireles , Silva Maria Eduarda Galvão , Brito Priscila Alcântara de , Ferreira José Airton Alves , Amaral Danielle Costa do , Lima Letícia Maria Cardoso de , Santos Gabriella Giacomini Allemany dos , Freire Gabriel Nascimento , Sousa Romana Brito Azevedo , Melo Antônio Boaventura Júnior Maciel , Oliveira Hilderlania Alves de , Junior Ely Cavalcante Lima , Lira José Wilker Linhares , Branco Luis Fernando de Lima Castelo , Silva Anderson Weiny Barbalho
Published: February 2025

A COVID-19, causada pelo SARS-CoV-2, afeta múltiplos órgãos, ocasionando complicações persistentes. O vírus entra pelo receptor ACE2, causando viremia e disseminação sistêmica. O presente estudo revisou a fisiopatologia da COVID-19 e suas complicações crônicas com base em 34 artigos publicados entre 2018 e 2024. O SARS-CoV-2 afeta vários sistemas, mesmo após a fase aguda da doença, resultando em sequelas crônicas. Complicações respiratórias incluem fibrose pulmonar e tempestade de citocinas que danifica o tecido pulmonar. No sistema cardiovascular, há risco de miocardite, trombose, insuficiência cardíaca e AVC. Neurologicamente, o vírus pode causar encefalite, neurodegeneração e síndromes neurológicas. O sistema musculoesquelético também é afetado, com perda de massa muscular e óssea, além de artralgia e atrofia. A resposta imune inata, embora ativada, é retardada pelo vírus, favorecendo cargas virais elevadas e casos graves. Esses efeitos prolongados requerem cuidados médicos contínuos e reabilitação. Conclui-se que a COVID-19 traz diversos desafios à saúde pública, demandando políticas de reabilitação e manejo das complicações a longo prazo.
Sosialisasi Hukum Ketenagakerjaan Berdasarkan Undang-Undang Ketenagakerjaan No 13 Tahun 2003
Authors: Salman  , Chandra Febrian
Published: February 2025

Sosialisasi hukum ketenagakerjaan berdasarkan Undang-Undang Nomor 13 Tahun 2003 menjadi penting dalam memberikan pemahaman kepada masyarakat tentang hak dan kewajiban tenaga kerja. Peningkatan pesat sektor industri membuka peluang kerja yang luas, sehingga banyak tenaga kerja bermigrasi ke daerah industri untuk mendapatkan pekerjaan dengan harapan memperoleh penghasilan yang layak. Namun, minimnya pemahaman terhadap regulasi ketenagakerjaan sering kali menyebabkan ketidaktahuan mengenai hak-hak dasar seperti upah minimum, jaminan sosial, serta aturan pemutusan hubungan kerja (PHK). Oleh karena itu, STIH YPM menyelenggarakan sosialisasi hukum ketenagakerjaan bagi masyarakat Desa Sungai Ulak untuk memberikan edukasi terkait regulasi ketenagakerjaan. Hasil kegiatan menunjukkan peningkatan kesadaran masyarakat terhadap aturan ketenagakerjaan dan pentingnya memahami kontrak kerja sebelum bekerja di perusahaan industri. Dengan adanya sosialisasi ini, diharapkan masyarakat dapat lebih memahami hak dan kewajibannya sebagai tenaga kerja, sehingga dapat terhindar dari eksploitasi di dunia kerja.
Sosialisasi Pembelajaran Daring bagi Mahasiswa pada Masa Pandemi
Authors: Kusaimah  , Pransisko Frengki
Published: February 2025

Seiring dengan masih berlangsungnya masa pandemi pada tahun tahun 2021 dan terjadinya lonjakan gelombang kedua pandemi, telah menyebabkan masyarakat terpaksa harus menjalani PPKM (menjaga jarak, tetap di rumah, bekerja di rumah, bahkan beribadah di rumah) selama berbulan-bulan. Coronaviruse Disease 2019 (Covid-19) juga berdampak terhadap proses belajar mengajar yang harus dilakukan secara jarak jauh, untuk melindungi keselamatan dan kesehatan para tenaga pendidik dan peserta didik dari ancaman Covid-19. STIH YPM telah memanfaatkan aplikasi pembelajaran jarak jauh dengan memberlakukan pembelajaran dalam jaringan. Atas latar belakang tersebut, maka prodi ilmu hukum STIH YPM memberikan sosialisasi dan pelatihan Pembelajaran Daring bagi Mahasiswa pada Masa Pandemi kepada Mahasiswa STIH YPM dengan judul Sosialisasi Pembelajaran Daring bagi Mahasiswa pada Masa Pandemi. Diharapkan dengan adanya sosialisasi dan pelatihan pembelajaran daring bagi mahasiswa pada masa pandemi ini akan menambah pengetahuan dan wawasan mahasiswa STIH YPM tentang pembelajaran daring, media pembelajaran daring, kegunaan, kekurangan, kelebihan dan cara penggunaan aplikasi dan lain sebagainya. Dengan begitu, mahasiswa mendapatkan pemahaman seputar pembelajaran daring dan Output diadakannya pembinaan ini pada akhirnya membuat mahasiswa antusias dan dapat memahami Pembelajaran Daring dan dapat menggunakan aplikasi ini dalam kegiatan perkuliahan maupun seminar nasional bahkan internasional yang diadakan dalam jaringan (online). Sasaran dalam pembinaan sosialisasi dan pelatihan ini adalah mahasiswa STIH YPM.
Sinergi Kewirausahaan Mahasiswa Universitas Merangin dan Kearifan Lokal: Solusi Inovatif untuk Pemberdayaan Masyarakat
Authors: Kusaimah  , Dahri Muhtar , Farhid Hidayah Maoren
Published: February 2025

Pemberdayaan masyarakat melalui kewirausahaan berbasis kearifan lokal merupakan pendekatan yang sangat relevan dalam meningkatkan kesejahteraan ekonomi di tingkat desa. Artikel ini bertujuan untuk mengeksplorasi sinergi antara mahasiswa Universitas Merangin dan potensi kearifan lokal dalam pemberdayaan masyarakat. Penelitian ini mengidentifikasi berbagai strategi untuk memanfaatkan kearifan lokal, seperti kerajinan tangan, kuliner, dan produk tradisional, yang dapat dikembangkan menjadi usaha kewirausahaan yang berkelanjutan. Selain itu, artikel ini juga membahas pentingnya inovasi dalam pengembangan produk berbasis kearifan lokal dan strategi pemasaran yang efektif melalui platform digital. Kolaborasi antara perguruan tinggi, pemerintah, dan masyarakat yang berlandaskan pada konsep Triple Helix dianggap sebagai faktor kunci dalam mempercepat proses pemberdayaan dan peningkatan ekonomi lokal. Penelitian ini menggunakan pendekatan kualitatif dengan pengumpulan data melalui wawancara, observasi, dan diskusi kelompok terfokus dengan masyarakat dan pelaku usaha lokal. Hasil penelitian menunjukkan bahwa dengan pemanfaatan inovasi dan kolaborasi yang baik, kewirausahaan berbasis kearifan lokal dapat memberikan dampak positif terhadap pemberdayaan ekonomi masyarakat.
Penyuluhan Pencegahan Pelecehan Seksual pada Anak Sekolah Dasar
Authors: Sasmita Ruwaiza , Melina Angra , Fathullah Saputra Dipo
Published: February 2025

Pelecehan seksual pada anak merupakan permasalahan serius yang dapat berdampak jangka panjang terhadap perkembangan psikologis korban. Penyuluhan ini bertujuan untuk meningkatkan kesadaran serta pemahaman anak-anak mengenai bahaya pelecehan seksual dan cara melindungi diri. Kegiatan dilakukan di SD Negeri 03 Kabupaten Merangin melalui metode sosialisasi interaktif dengan pendekatan story-telling, diskusi, dan permainan edukatif. Hasil kegiatan menunjukkan peningkatan pemahaman peserta mengenai batasan tubuh, jenis-jenis sentuhan yang tidak pantas, serta langkah-langkah yang harus dilakukan jika mengalami pelecehan. Penyuluhan ini diharapkan dapat menjadi langkah preventif dalam mencegah kasus pelecehan seksual di lingkungan sekolah.
Penyuluhan tentang Hukum Adat Kawin Lari pada Ibu-Ibu Pengajian
Authors: Kartika Sari Fitri , Fachrul Aljamili Muhammad
Published: February 2025

Penyuluhan mengenai hukum adat kawin lari kepada ibu-ibu pengajian di Sungai Piul Kelurahan Dusun Bangko bertujuan untuk meningkatkan pemahaman masyarakat tentang pengaturan perkawinan dalam hukum adat dan implikasi hukumnya. Kawin lari, sebagai tradisi yang berkembang dalam beberapa komunitas, sering kali dihadapkan pada tantangan hukum, baik itu hukum negara maupun hukum adat. Penyuluhan ini menyasar ibu-ibu pengajian karena mereka memegang peran penting dalam menyebarkan informasi kepada keluarga dan masyarakat sekitar. Program penyuluhan ini mencakup penjelasan mengenai dasar hukum adat, dampak sosial, serta cara penyelesaian masalah kawin lari dalam perspektif hukum Islam dan hukum negara. Dengan pendekatan yang berbasis pada dialog interaktif, peserta diberikan kesempatan untuk bertanya dan berdiskusi, sehingga tercipta pemahaman yang lebih dalam tentang pentingnya penghormatan terhadap hukum yang berlaku. Hasil dari kegiatan ini diharapkan mampu memberi kontribusi positif terhadap peningkatan kesadaran hukum di kalangan masyarakat setempat dan dapat mengurangi potensi penyalahgunaan tradisi kawin lari.
Exploring The Factors Affecting Dropout Rates In Higher Education Institutions In India
Authors: Solanki Meenu
Published: February 2025

The phenomenon of student dropout in higher education institutions (HEIs) in India has garnered significant attention due to its profound implications on individual career prospects and the broader socio-economic landscape. This paper delves into the multifaceted factors contributing to high dropout rates within Indian HEIs. By analyzing socio-economic backgrounds, academic preparedness, institutional support systems, psychological factors, and external influences, the study aims to provide a comprehensive understanding of the underlying causes. Utilizing a combination of quantitative data analysis and qualitative case studies, the research identifies key areas where interventions can be most effective. The findings highlight the critical role of accessible financial aid, robust academic support services, and mental health resources in mitigating dropout rates. Additionally, the study underscores the importance of fostering an inclusive and supportive educational environment. The conclusions drawn offer actionable insights for policymakers, educational administrators, and stakeholders committed to enhancing student retention and success in India’s higher education sector.
Synthesizing Organic Compounds With Asymmetry Using Organocatalysts
Authors: kaur Varleen
Published: February 2025

The synthesis of chiral organic compounds with high enantiomeric purity is pivotal in various fields, including pharmaceuticals, agrochemicals, and materials science. Organocatalysts have emerged as a sustainable and efficient alternative to traditional metal-based catalysts, offering advantages such as low toxicity, environmental friendliness, and operational simplicity. This paper synthesizes existing secondary data to explore the advancements in asymmetric synthesis using organocatalysts. It delves into the mechanisms, types of organocatalysts, and their applications in creating enantiomerically enriched compounds. Furthermore, the paper discusses the challenges and future prospects of organocatalysis in asymmetric synthesis. By providing a comprehensive literature review, this study underscores the significance of organocatalysts in modern synthetic chemistry and highlights the potential for future innovations in the field.
Some Contribution In Optimization Uunder Generalized Convexity
Authors: Vinod Vinod
Published: February 2025

Optimization under generalized convexity has emerged as a pivotal area in mathematical programming, extending classical convex analysis to encompass a broader spectrum of problems. This paper synthesizes existing secondary data to explore recent advancements and contributions in the field of optimization under generalized convexity. It delves into various generalized convexity concepts, including pseudo-convexity, quasi-convexity, and invex functions, and examines their applications in solving complex optimization problems. The literature review highlights key theoretical developments, algorithmic innovations, and practical applications across diverse domains such as economics, engineering, and machine learning. Additionally, the paper discusses the challenges and future prospects of optimization under generalized convexity, emphasizing the need for further research to enhance solution methodologies and extend applicability. By providing a comprehensive overview of the current state of the field, this study underscores the significance of generalized convexity in advancing optimization theory and practice.
Empowering Rural Communities Through Digital Literacy Initiatives in India
Authors: Digvijay Pandey
Published: February 2025

India, as one of the countries with the largest population in the world, faces major challenges in increasing digital literacy in rural areas. Inequality of access and understanding of information technology can hinder social and economic development in rural communities. Therefore, community service through digital literacy initiatives is important to overcome this problem. This article aims to document and analyze community service efforts in increasing digital literacy in rural Indian communities. The main goal is to empower rural communities with basic skills and knowledge of digital technologies so they can access educational opportunities, employment, and online services more effectively. The service method uses Asset Bassed Community Development (ABCD) involving collaboration between educational institutions, non-governmental organizations, and local communities. These programs include practical training, workshops, and access to digital resources. The results of this service showed a significant increase in understanding of digital technology among the participating rural Indian communities. Program participants actively use digital devices for educational purposes, job searches, and communicating with government and health services. Additionally, there is increasing awareness of the economic potential that can be gained through digital literacy skills. So, it is concluded that digital literacy initiatives that focus on community service have great potential to empower rural communities in India. Through collaboration between various parties, rural communities can be given the tools they need to participate in the digital era, reducing inequality of access and opening the door to new opportunities. This article underscores the continued importance of such community service efforts to support inclusive development in India.
Land Optimization to Improve the Economy through Attractive Tourist Destinations in Smart City Indonesia
Authors: Asfahani Asfahani  , Tono Mahmudin  , Zohaib Hassan Sain
Published: February 2025

Increasing urbanization and technological developments have triggered significant transformations in urban land management, especially in Indonesia's Smart City. This study aims to formulate and implement land optimization strategies by developing attractive tourist destinations in Smart City, Indonesia. This community service research method uses the ABCD (Asset Based Community Development) method, which prioritizes valuable aspects owned by a community, better known as an asset-based approach, with five stages: Discovery, Dream, Planning, Define, and Destiny. The results provide a comprehensive view to support the development of tourist destinations responsive to smart cities in Indonesia, marking an important contribution to sustainable and innovative city development. So, it is concluded that developing smart and sustainable tourist destinations is crucial in maximizing land use in Indonesia's Smart Cities. The integration of smart technology, community participation, and environmental sustainability are key elements in creating tourist destinations that are not only attractive but also contribute to local economic growth and environmental preservation.
Therapeutic Communication As A Solution To Overcome Adolescent Problems
Authors: Listia Dwi Febriati  , Zahrah Zakiyah  , Tutik Astuti  , Ester ratnaningsih
Published: February 2025

This community service aimed to enhance parents' knowledge and therapeutic communication skills regarding adolescent issues in Padukuhan Duku, Jambidan Village. Conducted on August 1, 2023, the activity involved 17 parents, focusing on adolescent problems and solutions through counseling. Findings revealed a positive shift in knowledge levels, with a significant increase in the "Good" category from 70.59% to 82.35%. The paired sample T-test indicated a significant difference (p=0.024) between pre-test and post-test knowledge levels. The majority of participants were over 36 years old, had secondary education, and were not working. This community service contributes to the understanding of the critical role parents play in shaping adolescents' development, emphasizing the importance of effective communication. The success of the intervention suggests its potential applicability to similar community initiatives. In conclusion, the activity effectively increased parents' knowledge and therapeutic communication skills, highlighting the significance of continuous parent-adolescent communication for reproductive health knowledge and overall well-being.
Green Innovation: The Vital Role of Go Green Communities in Pakistan's Environmental Conservation
Authors: Waseem Ahmed Khattak
Published: February 2025

Pakistan faces significant environmental challenges, including waste mismanagement, deforestation, and urban pollution, which threaten ecological sustainability and public health. In response, Go Green communities have emerged as grassroots movements promoting green innovation and environmental conservation. This community engagement initiative aimed to enhance environmental awareness, encourage sustainable practices, and foster participatory action among local communities. The study utilized the Participatory Action Research (PAR) approach, emphasizing collaboration, capacity-building workshops, and hands-on environmental activities such as waste management, afforestation, urban gardening, and policy advocacy. The results demonstrated increased community involvement in eco-friendly initiatives, with tangible outcomes such as the establishment of waste segregation systems, enhanced green spaces, and improved local sustainability efforts. Additionally, the advocacy component of the initiative led to greater municipal recognition of community-driven environmental strategies, inspiring broader policy discussions. However, challenges such as financial limitations, resistance from industries, and restricted access to green technologies highlighted the need for stronger institutional support. This study contributes to the field of sustainable development and green innovation by showcasing how grassroots environmental movements can drive ecological transformation through participatory engagement.
Mentoring Student Nurses – Are Nurses Prepared, Recognized, and Supported to Teach Nursing Students in Clinical Settings?
Authors: Yasir Ali  , Saeeda Khan  , Ghulam Mustafa  , Khadim Hussain  , Ambreen Akhter
Published: February 2025

Background: Clinical teaching and supervision of undergraduate nursing students is one continuous, high volume, high impact responsibility of registered nurses at clinical environment. Objective: The objective of the study was to identify the level of preparedness, recognition and support in their role to teach and supervise the nursing students. Methodology: A cross-sectional study was conducted at a tertiary care hospital in Karachi, Pakistan, from July to October, 2023. The convenient sampling technique was used to collect data followed by written informed consent, calculated sample size was 81. All the RN, GBSN, Post-RN BSN, MSN nurses having valid PNC license and working at clinical setting were included and those nurses who were already involved in teaching were excluded. Data were analyzed via SPSS version 26.0. Results: Among all participants, 51% (n=41) were aged between 25-45 years, 48.1% (n=39) were males and 51.9% (n=42) were females participated in the study. Out of the total participants, 37.0% (n=30) of participants from Post RN BSN and 4.9% (n=4) of the participants from Master of Science in Nursing (MSN). 43.2% (n = 35) was the number of respondents who had previous experience of supervising. Conclusion: The current model of clinical placement has to be revised due to the growing difficulty of the practice environment, the rise in need of the nursing student’s professional growth and the hopes placed on RNs.
Prevalence and Risk Factors of Hepatitis A, B and C in Neelum Valley District of Azad Kashmir, Pakistan
Authors: Tasleem Akhtar  , Syed Ayaz Kazmi  , Abdul Rauf  , Beenish Shahid  , Roop Riaz  , Muhammad Zahid Latif  , Sundus Khawaja  , Hassan Abdullah  , Iqra Batool  , Salma Farooq  , Zeeshan Anjum
Published: February 2025

Background: No prior studies have assessed hepatitis A, B, and C prevalence in Neelum Valley, Azad Kashmir, a major tourist hub along the Line of Control. This study evaluates the prevalence and risk factors associated with these infections in the region. Methods: A total of 374 participants (286 males, 88 females) from Neelum Valley were surveyed, and serum samples were tested for hepatitis markers using immuno-chromatographic tests and Real-Time PCR. Liver function markers (ALT, ALP, and Bilirubin) were also analyzed. Statistical analysis was conducted using GraphPad Prism V. 7.04. Results: The prevalence of recent hepatitis A infection (HAV IgM Positive) was 0.8%, while 4.8% had prior exposure (HAV IgG Positive). Hepatitis B (HBsAg positivity) was detected in 2.4%, with 1.3% showing active viral replication (HBV DNA Positive). Hepatitis C exposure (anti-HCV positivity) was 1.3%, with 0.5% showing active infection (HCV RNA Positive). All participants had normal liver function markers. Younger individuals (18–25 years) had higher infection rates, and males showed a greater prevalence than females for all infections. Significant risk factors (p < 0.0001) included contaminated food or water, jaundice history, hospitalization, blood transfusions, ear/nose piercing, tattooing, and treatment from local practitioners. Conclusions: The prevalence of hepatitis A, B, and C in Neelum Valley is lower than in some regional studies but remains a public health concern. The influx of tourists may facilitate disease transmission, highlighting the need for improved sanitation and healthcare measures.
In-Silico Analysis of Genetic Mutations in BRAF and PMS2 for Biomarker Discovery to Transform Colorectal Cancer Research
Authors: Nusrat Jahan  , Arslan Arshad  , Samd Ullah  , Humera Nazir  , Iftikhar Ud Din  , Muhammad Hammad Zafar  , Shaista Shafiq  , Faheem kanwal  , Muhammad Azmat  , Imran Zafar
Published: February 2025

Point mutations in the PMS2 and BRAF genes have emerged as critical drivers of colorectal cancer, influencing key cellular processes such as mismatch repair and signal transduction. Understanding the impact of these mutations at the molecular level is essential for advancing cancer diagnostics and therapies. This study leverages advanced bioinformatics tools to systematically identify and evaluate potentially deleterious single nucleotide polymorphisms (SNPs) in the coding regions of PMS2 and BRAF. Using SIFT, PolyPhen-2, and I-Mutant 2.0, we assessed the functional impact of 2412 SNPs in PMS2 and 453 SNPs in BRAF. From these, 32 mutations in PMS2 and one in BRAF were predicted to be highly deleterious, with significant implications for protein stability and function. Specifically, PMS2 mutations such as c.137G>T (p.Ser46Ile) and c.383C>T (p.Ser128Leu) were found to disrupt the protein structure, potentially impairing its role in mismatch repair. The BRAF mutation V600E was identified as highly damaging, consistent with previous studies that associate it with oncogenic activation in several cancers. These results highlight the importance of computational approaches in predicting the pathogenicity of genetic mutations and their potential as therapeutic targets in colorectal cancer. This study establishes a foundation for future experimental and clinical research aimed at evaluating the therapeutic potential of targeting specific SNPs in colorectal cancer. Computational analysis identified 21 deleterious SNPs in PMS2 and one in BRAF, which may disrupt protein function. These findings underscore their potential significance in colorectal cancer progression and targeted therapeutic strategies.
الإطار القانوني لمكافحة جريمة الرشوة في لبنان
Authors:   طالبة دكتوراه سنة ثالثة في القانون العام / الجامعة الاسلامية في لبنان, محيش قمر جمال , الخير البروفيسور / خالد ,   الجامعة اللبنانية
Published: February 2025

تعتبر جريمة الرشوة واحدة من أبرز التحديات التي تواجه جميع دول العالم، حيث أنها تشكل خطرا كبيرًا على نزاهة المؤسسات العامة والخاصة على حد سواء.
وفي السياق اللبناني، تلعب الرشوة دوراً لا يُستهان به في تقويض جهود الإصلاح الإداري، وتعتبر الإدارة العامة البيئة الحاضنة لهذه الظاهرة مما يعكس أزمة ثقة كبيرة بين المواطنين والدولة. ومن أكبر التحديات التي تعيق التنمية في القطاع الخاص ووتترك آثاراً سلبيةً كثيرة على المجتمع ولهذا السبب أصبحت قضية مكافحة الرشوة أمراً ضرورياً، مما يؤدي إلى استجابة قانونية فاعلة للعمل على مكافحتها.
يأخذنا هذا الواقع إلى طرح جملة من التساؤلات: كيف تدارك القانون اللبناني هذه الظاهرة في القطاعين العام والخاص؟ وما هي أبرز الاقتراحات التي تساهم في الحد منها وتفعيل دور القوانين المتعلقة بها؟
وقد خلصنا من خلال هذا البحث الى تقديم دراسة تحليلية دقيقة للأطر القانونية والأسس العامة لجرم الرشوة في لبنان بدءاً من البنيان القانوني وصولاً الى العقوبة المفروضة عليها في القطاعين العام والخاص من خلال استعراض النصوص القانونية التي أوردها المشرع اللبناني في هذا المجال بهدف الحد منها والعمل على مكافحتها وتطهير المؤسسات العامة منها.
ونظراً لما للرشوة من آثار كبيرة ومتنوعة من إضعاف الاقتصاد، وفقدان الثقة في المؤسسات الحكومية والخاصة، وتدهور مستوى الخدمات الاجتماعية وتدني مستوى المعيشة للأفراد وتعطيل للتنمية من خلال عرقلة المشاريع التنموية والاستثمارية حيث تتوجه الموارد إلى قنوات غير قانونية، فبالتالي إن آثار الرشوة تتجاوز الفرد لتطال المجتمع ككل، مما يستدعي العمل على تفعيل الأطر القانونية التي وُجدت لمكافحتها من خلال تقديم جملة من الاقتراحات والتوصيات التي تساهم في تفعيل القوانين وسد أي ثغرات قانونية يمكن أن تؤدي إلى إضعاف دورها في مكافحة هذا الجرم.
Environmental Laws and Artificial Intelligence as Promising Tools for Tackling Climate Migration
Authors:   Faculty of Law, Islamic University of Lebanon, Mcheik Mohamad Fayad , khalifeh Adel ,   Lebanese Universty faculty of law
Published: February 2025

Environmental migration is becoming a reality due to climate change caused by human activities. Environmental migrants, also known as climate migrants, are individuals forced to leave their usual homes, either temporarily or permanently, and relocate within or outside their home country as a result of sudden or progressive climate change. These environmental alterations negatively impact their lives or living conditions. The term “environmental migrant” was used by the United Nations Environment Program (UNEP) in Nairobi in 1985, and member states of the International Organization for Migration reached an agreement on a working definition in 2007. This definition reflects a growing understanding of how the environment and climate affect migration patterns. Given the proven efficacy of artificial intelligence (AI) across various disciplines, the study aims to show how AI can be applied to improve and implement sustainable development plans. The United Nations has set 2030 as the deadline for achieving all of these goals. This research presents the available environmental legislation on both international and regional levels and provides a comparative analysis of these regulations. Moreover, the role of AI in tackling the obstacles associated with environmental mobility is investigated as well.
Egyptian-Saudi Strategic Integration: A Vision for the Future of International Challenges
Authors:   Master2 public administration and strategic planning _ Lebanese university, Abo Daya Malak
Published: February 2025

The Kingdom of Saudi Arabia and Egypt are significant political and economic powers in the Middle East. As the region faces challenges due to the Gaza war and the need to protect national security, a study focuses on strategic integration between the two countries. The study analyzes their geostrategic importance and bilateral cooperation, highlighting their positions on international issues and complementarities. It also explores opportunities for cooperation and proposes strategies to optimize Saudi-Egyptian relations for a safer, sustainable, and prosperous Arab community.
موانع المسؤولية عن التعويض المجبر للضرر
Authors:   الجامعة الإسلامية في لبنان, سرهيد فاضل مهدي
Published: February 2025

عند دراسة التاريخ القانوني يتضح أنه إذا أتلف شخص أو أضر بمال الغير أو سبب له ضرراً في ماله كانت القوة هي التي تحكم ذلك التصرف، ثم انتقلت تلك المهمة إلى القوانين الوضعية والتي تمثلت بالقوانين المدنية.
فالقانون المدني يتولى إنشاء الالتزام ويحدد أركانه ومداه والجزاء المترتب على مخالفته، بحيث يقتضي أن يعوض للغير عما اقترفه من أخطاء سببت ضررا لهم.
لكن في بعض الأحيان هناك موانع للمسؤولية عن التعويض المجبر للضرر، كالتقادم باعتباره مانع قانوني من سماع دعوى التعويض، والقوة القاهرة، وخطأ الغير، وخطأ المتضرر.
The Malacca Saltanate: Power Struggle between Tun Ali and Tun Perak (1445-1456)
Authors:   University of Dhaka, Azad Md. Abul Kalam
Published: February 2025

The Malacca Sultanate (established in 1402 as a port-kingdom however; it become known as the Malacca Sultanate since 1445) saw an extraordinary incident in its history. In 1445, a far-reaching bloody coup d’état took place and the coup permanently changed the features of politics of the kingdom. Following the coup, a non-Malay Tamil and the leader of the coup d’état named Tun Ali was appointed as the Bendahara or Prime Minister of the Malacca Sultanate by the new ruler Sultan Muzaffar Shah. Before long, he got involved in a power struggle and political rivalry with Tun Perak, a member of the former Bendahara family of Malacca. Once started, the political rivalry between Tun Ali and Tun Perak took a serious turn. The Sultanate was in danger of being destroyed due to their intensive and prolonged power struggle (1445-1456). However, Sultan Muzaffar Shah’s meticulous and skillful management of the situation resulted in a peaceful end to the ten-year power struggle. This article first sheds light on the background of the power struggle and then highlights Sultan Muzaffar Shah’s masterful handling of the circumstances for which a peaceful resolution of the struggle was possible. The primary sources including two versions of the Sejarah Melayu (The Malay Annals) and Tome Pires’ the Suma Oriental are used to prepare this research article; however, secondary sources are also consulted.
Post Colonial Approaches Reflected in the Works of Bangladeshi Female Artists
Authors:   Jagannath University, Dhaka, Khnam Mahmuda
Published: February 2025

Post colonialism is a modern phenomenon; a much talked about one in the art circle especially since the 1960’s. Co-incidentally, the journey of Bangladeshi women painters also started during the same time-frame. It is obvious that aspects of decolonization are Omni-present in the works of the active women artists of Bangladesh. It is reflected in their choice of themes, images, and symbols that do not imitate colonial approaches, influencing the academic art of Bangladesh since the eighteenth century. This paper is an attempt to find out how this change took place, why especially the women artists have played a more active role in formulating a new vocabulary to counter the euro-centrism that was and is so strongly present in the art circle here. In doing so, mainly the exhibition catalogues of the major events are analyzed with the help of interviews with the artists themselves.
বাংলায় পাশ্চাত্য শিক্ষা নীতি প্রণয়নে মেক‌ওলের প্রভাব (Influence of Macaulay in the Formation of Western Education Policy in Bengal)
Authors:   University of Dhaka, Choudhury H M Jalal Uddin
Published: February 2025

The East-India Company government tried to appease Bengal by establishing first the Calcutta Madrasa in 1781 and the Benares Sanskrit College in 1792. The nature of teaching in both the institutions, religious and secular, enabled the state to make both the Hindu and Muslim communities of the country understand the purpose and importance of education, while the goal of education for the individual was mainly self-improvement and global improvement, the state's objective was quite different. The main aim of the state intervention was to create a dedicated attendant class of the state. Those who will work for the rulers in revenue, justice and other matters. As a result, a special class was being integrated through education in company-ruled Bengal, not as a nation. Although the development of such education could be seen as enlightening, but it could not play a role in creating the context for a social and cultural revolution. Rather, education itself became a social dividing line. The literate-illiterate class gap developed under British rule was unprecedented. At the initial stage, the company government expressed reluctance to take responsibility for the education of Indians, but the Court of Directors and Member of Parliament Charles Grant formed an evangelist movement called the Clapham Sect and continued to pressurize Parliament to carry out missionary activities on Indians. However, after 1823, the Anglo-Orientalist conflict between Indian education and Western advanced literature and science practice began. According to some anylizer, the crisis between the Anglophones and the Orientalists in this dispute is not mainly about the purpose of education but about its means. The inclusion of C. E. Trevelyan and T. B. Macaulay on the Education Committee in 1834 combined utilitarian and evangelical approaches to educational problems. Besides, the position of the Anglicist party also became very strong. As a result, the negative impact of British attitude towards Indians became very evident. Finally, in 1835, Macaulay's proposal was accepted. The main theme of which was to create a loyal class of so-called literates in English education. Whose devotion to Lord will be eternal and full of gratitude. Who will not care about the loss of the value of their own land, but will always be busy with the gains of the British Empire. The cause of which was by no means spiritual but entirely material. Besides, in 1837 the perfect combination of the state language replaced Persian with English.
ফিলিস্তিনে হামাসের উত্থান ও রাজনৈতিক চ্যালেঞ্জসমূহ (Rise of Hamas in Palestine and Its Political Challenges)
Authors:   Bangladesh Open University, Karim Md. Ali
Published: February 2025

The state of Israel was born in 1948 with the help of western powers. As a consequence, a longterm and critical crisis was created in the Middle-East. Israel occupied the land of Palestine and has been continuously setting up Jews settelment illegally after the victory of Arab-Israel six days war in 1967. As a result, a constant change is taking place in the map of Palestine. With the help of military powers Israel has been extending its boundary overlooking the sovereignty of Palestine. In responce to that the First Intifada (Protest Movement) started in 1987-1991 as Palestinian movement against Israeli occupation. In the midst of Intifada, Hamas was born in 1987 under the leadership of Palestinian leader Sheikh Ahmed Yeasin. In 1993 with the mediation of the USA an agreement between Palestine Liberation Organization (PLO) and Israel was signed which is known as the Oslo Accords; however, it failed to protect or serve the interest of the Palestinians. For that Hamas has been opposing the Oslo Accords. Eventually, Hamas started their protest against Israel in 2000-2004, which they called the Second Intefada. Later on, political rivalry between Hamas and PLO began following the 2006 general eletion in Gaza. Now Hamas is facing different political challanges and controlling the administration of Gaza Strip. Despite internal conflicts with the PLO and external conflicts with Israel on several occasions, Hamas is increasingly strengthening its position by facing various internal political challenges in line with managment of the administration of Gaza and the resistance movement againest Israeli aggression. Hamas is also strengthening its position by establishing relations with various states of the globe.
Beyond Traditional Investing: Navigating the Digital Frontier with Financial Literacy, Experience, Behavioural Finance, and Fintech Tools
Authors: Pinisetty Ram Kishore ,   Research Scholar, VIT-AP School of Business, VIT-AP University, Amaravati, Andhra Pradesh, India., * Raghavendra ,   Professor & Associate Dean, VIT-AP School of Business, VIT-AP University, Amaravati, Andhra Pradesh, India.
Published: February 2025

Many investors believe that fintech can transform the financial sector by introducing greater
transparency and safety, as it eases the exchange of products and services, expands its service
provider footprint, and provides superior risk mitigation. Fintech might expand quickly because
investors are willing to utilise their money to lower risk. However, it is worth noting that few
individual fintech investors are diversifying their holdings. Only 36% of all individual investors in
India use fintech investing platforms. This underscores the need to comprehend that certain factors
might impact investing choices without financial technology assistance. Regardless of the use of
fintech, essential variables, including investor knowledge, financial behaviour, financial literacy,
and financial experience, may greatly influence decision-making in investments. This study employs
quantitative methods to investigate the research concerns methodically, prioritising unbiased
measurements and analysing the collected data. 200 people participated in the study, and SPSS
was used to process the data. This study aims to yield significant insights for stakeholders, such as the Indian government, fintech groups, particularly those involved in the digital payments domain, and fintech platform users.
Investor Perception Towards Initial Public Offerings and Its Impact on IPO Under-pricing in India
Authors: B Bharathi ,   Assistant Professor of Commerce & Research Supervisor, Srimad Andavan Arts and Science College (Autonomous), Tiruchirapalli, Affiliated to Bharathidasan University, Tamilunadu – 620005., K R Gopala ,   Research Scholar, Srimad Andavan Arts and Science College (Autonomous), Tiruchirapalli, Affiliated to Bharathidasan University, Tamilunadu – 620005
Published: February 2025

The research is carried out to understand the IPO under-pricing status and examine the impact
of investor perception on the under-pricing of IPOs in India. Three hypotheses were formulated
and tested to decide the status of IPO under-pricing and factors influencing IPO under-pricing
in India. Data has been collected for 217 IPOs issued from 2018 to 2023. Statistical tools like
‘descriptive statistics’, ‘Pearson correlation analysis’, ‘one sample t-test’, ‘regression analysis’ and
‘independent sample t-test’ are used. The study findings show that recent IPOs in India exhibit
significant under-pricing (p-value 0.000 < 0.05), demonstrating the presence of IPO under-pricing
in the Indian primary market. The observed mean under-pricing rate for high subscription status
IPOs is 58.248%, and for low subscription status, it is 5.988%, depicting a statistically significant
difference.
Further, Pearson correlation analysis confirms the strong positive correlation (r = 0.714, p < 0.01)
between investor perception and the IPO under-pricing rate. The total subscription rate significantly
influences IPO under-pricing (p = 0.000, coefficient = 0.491). This study concludes that increased
positive investor perception leads to increased investor participation in IPOs, resulting in higher
IPO subscription rates. An increased IPO subscription rate reduces the chances of IPO allotment,
and un-allotted investors try to purchase the shares in the secondary market on the day of listing,
which increases the listing price and results in IPO under-pricing.