bluuebunny/crossref_metadata_2025 huggingface dataset:
Exploring different health care providers´ perceptions on the management of diarrhoea in cholera hotspots in the Democratic Republic of Congo: A qualitative content analysis
Authors: Schedwin Mattias , Furaha Aurélie Bisumba , Hildenwall Helena , Elimian Kelly , Malembaka Espoir Bwenge , Yambayamba Marc K. , Forsberg Birger C. , Van Damme Wim , Alfvén Tobias , Carter Simone E. , Okitayemba Placide Welo , Mapatano Mala Ali , King Carina
Published: March 2024

Global cholera guidelines support wider healthcare system strengthening interventions, alongside vertical outbreak responses, to end cholera. Well-trained healthcare providers are essential for a resilient health system and can create synergies with childhood diarrhoea, which has higher mortality. We explored how the main provider groups for diarrhoea in cholera hotspots interact, decide on treatment, and reflect on possible limiting factors and opportunities to improve prevention and treatment. We conducted focus group discussions in September 2022 with different healthcare provider types in two urban and two rural cholera hotspots in the North Kivu and Tanganyika provinces in the Eastern Democratic Republic of Congo. Content analysis was used with the same coding applied to all providers. In total 15 focus group discussions with medical doctors (n = 3), nurses (n = 4), drug shop vendors (n = 4), and traditional health practitioners (n = 4) were performed. Four categories were derived from the analysis. (i) Provider dynamics: scepticism between all cadres was prominent, whilst also acknowledging the important role all provider groups have in current case management. (ii) Choice of treatment: affordability and strong caregiver demands shaped by cultural beliefs strongly affected choice. (iii) Financial consideration on access: empathy was strong, with providers finding innovative ways to create access to treatment. Concurrently, financial incentives were important, and providers asked for this to be considered when subsiding treatment. (iv) How to improve: the current cholera outbreak response approach was appreciated however there was a strong wish for broader long-term interventions targeting root causes, particularly community access to potable water. Drug shops and traditional health practitioners should be considered for inclusion in health policies for cholera and other diarrhoeal diseases. Financial incentives for the provider to improve access to low-cost treatment and investment in access to potable water should furthermore be considered.
Can routine assessment of older people’s mental health lead to improved outcomes: A regression discontinuity analysis
Authors: Baird Kalpita , Byrne Ailish , Cockayne Sarah , Cunningham-Burley Rachel , Fairhurst Caroline , Adamson Joy , Vernon Wesley , Torgerson David J. ,   on behalf of the REFORM trial
Published: March 2024

Objective

To assess whether case finding for depression among people aged 65 and above improves mental health.

Design

Opportunistic evaluation using a regression discontinuity analysis with data from a randomised controlled trial.

Setting

The REFORM trial, a falls prevention study that recruited patients from NHS podiatry clinics.

Participants

1010 community-dwelling adults over the age of 65 with at least one risk factor for falling (recent previous fall or fear of falling).

Intervention

Letter sent to patient’s General Practitioner if they scored 10 points or above on the 15-item Geriatric Depression Scale (GDS-15) informing them of the patient’s risk of depression.

Main outcome measure

GDS-15 score six months after initial completion of GDS-15.

Results

895 (88.6%) of the 1010 participants randomised into REFORM had a valid baseline and six-month GDS-15 score and were included in this study. The mean GDS-15 baseline score was 3.5 (SD 3.0, median 3.0, range 0–15); 639 (71.4%) scored 0–4, 204 (22.8%) scored 5–9 indicating mild depression, and 52 (5.8%) scored 10 or higher indicating severe depression. At six months follow-up, those scoring 10 points or higher at baseline had, on average, a reduction of 1.08 points on the GDS-15 scale (95% confidence interval -1.83 to -0.33, p = 0.005) compared to those scoring less than 10, using the simplest linear regression model.

Conclusion

Case finding of depression in podiatry patients based on a GDS-15 score of 10 or more followed by a letter to their General Practitioner significantly reduced depression severity. Whether this applies to all older patients in primary care is unknown. Further research is required to confirm these findings. Regression discontinuity analyses could be prespecified and embedded within other existing research studies.
Canadian Critical Luxury Studies: Decentring Luxury, Jessica P. Clark and Nigel Lezama (eds) (2022)
Authors: Delgado Henry Navarro
Published: March 2024

Review of: Canadian Critical Luxury Studies: Decentring Luxury, Jessica P. Clark and Nigel Lezama (eds) (2022)

Bristol: Intellect Ltd, 248 pp.,

ISBN 978-1-78938-515-1, h/bk, $93.84

ISBN 978-1-78938-517-5, e-book, $80.00
Island Time: New Zealand’s Pacific Futures, Damon Salesa (2017)
Authors: Ryan Tom
Published: March 2024

Review of: Island Time: New Zealand’s Pacific Futures, Damon Salesa (2017)

Wellington: Bridget Williams Books, 256 pp.,

ISBN 978 1 98853 353 7 (pbk), NZ$17.99
Can Latin American Voters see the Future?
Authors: Thompson-Collart Brian , Dufresne Yannick , Brie Evelyne
Published: March 2024

The present study examined whether Argentinian citizens could predict election results at the sub-national level. We targeted Argentinian Twitter users in seven provinces with polls using Twitter Ads. Argentinian Twitter users constitute a high-ability subgroup that possesses several characteristics that enhance citizen forecasting competence. The polls asked citizens to predict what party would win the first round of the upcoming presidential election in their province. We present a preliminary citizen forecast of the first round of the 2023 Argentinian presidential election. The forecast demonstrates three preliminary findings. First, citizens expect a competitive election in their respective provinces. Second, citizens in almost all the provinces expect an opposition victory. Finally, a high degree of uncertainty surrounds these predictions, with no party obtaining a greater than 50 percent probability of winning in any of the provinces.
Estado do conhecimento sobre iniciação científica na educação básica
Authors: Oliveira Victor Hugo Nedel Oliveira , Vasques Daniel Giordani
Published: March 2024

A Iniciação Científica presente na escola básica configura-se como importante espaço de construção de conhecimentos relacionados ao campo da ciência, do método científico e da produção de saberes nas mais variadas áreas da ciência. O principal objetivo da presente investigação foi construir um estado do conhecimento sobre Iniciação Científica na educação básica. Para tanto, realizou-se pesquisa bibliográfica em formato de estado do conhecimento, com recorte temporal adotado entre os anos de 2010-2020, tendo sido selecionadas as bases de dados: IBICT (para teses e dissertações); Google Acadêmico e Scielo (para artigos científicos). Os descritores para composição do corpus da pesquisa foram: “Pesquisa”; “Iniciação Científica”; “Escola”; “Educação Básica”; “Iniciação Científica Júnior”. Os resultados demonstraram a presença de 18 artigos científicos, 05 dissertações e 05 teses. A análise descritiva demonstrou a concentração dos estudos na região concentrada Sul-Sudeste, bem como a recorrência das universidades federais na sua produção. A maior parte dos estudos contou com análise documental, seguida de entrevistas e observações, como recursos de coleta de dados. As conclusões dos estudos apresentaram as potencialidades da IC na formação e motivação dos estudantes, mas também ressaltaram preocupação com a formação pedagógica docente, bem como suscitaram reflexões sobre a importância da educação científica na contemporaneidade.  É possível considerar, portanto, que a presença de práticas de Iniciação Científica na educação básica colabora significativamente na formação critica e cidadã dos estudantes, fomentando o debate em torno da ciência, necessidade cada vez maior no contemporâneo.
Stigma, Bias, and the Shortfalls of Body Mass Index: A Reflection on the State of Weight Management
Authors: Papademetriou Marianna , Riehl Megan , Schulman Allison R.
Published: March 2024

Obesity is a complex, multifactorial chronic disease. With the development of novel endoscopic techniques and devices for the treatment of obesity, combined with expanding indications for medications, gastroenterologists are more involved in weight management than ever before. Despite the modern definition of obesity as a disease, weight bias and stigma are pervasive in the medical community and beyond. These sentiments contribute to worse outcomes for patients. Furthermore, body mass index (BMI), which is the primary metric to define obesity, does not always approximate visceral adiposity in all populations. A weight-centric model of health, which relies on BMI, misclassifies individuals who may be metabolically healthy at elevated weights. This review will summarize the history of BMI, highlight the problems that arise with a weight-centric model of health, and propose alternative weight-inclusive frameworks for assessment and intervention.
Outcomes After Fecal Microbiota Transplantation in Combination With Bezlotoxumab for Inflammatory Bowel Disease and Recurrent Clostridioides difficile Infection
Authors: Allegretti Jessica R. , Axelrad Jordan , Dalal Rahul S. , Kelly Colleen R. , Grinspan Ari , Fischer Monika
Published: March 2024

Fecal microbiota transplantation (FMT) prevents recurrent Clostridioides difficile infections (rCDI) in patients with inflammatory bowel disease. Bezlotoxumab is also indicated to prevent rCDI. We assess the impact of FMT in combination with bezlotoxumab in patients with inflammatory bowel disease and rCDI. We conducted a multicenter randomized placebo-controlled trial. All received a single colonoscopic FMT. Patients were randomized 1:1 to receive bezlotoxumab or placebo. Sixty-one patients were enrolled (30 received treatment and 31 received placebo). Overall, 5 participants (8%) experienced a CDI recurrence; 4 in the treatment arm, 1 in the placebo arm (13% vs 3%, P = 0.15). There was no clear benefit to the combination approach compared with FMT alone.
Moderating Resistances: The Reproduction of Muslim Religious Space in the Dutch East Indies
Authors: Faizi Fuad
Published: March 2024

This study seeks to historically elaborate on the roots of moderate Islam, focusing on the productive practices towards religious spaces in the Dutch colonial periods in the East Indies. It analyses the strategic changes in the Dutch reproduction of religious space during the Aceh War and the Sarekat Islam periods. The author argues that the Dutch government frequently seized Muslim religious space to secure its colonial power. The colonial government reproduced Muslim religious space in these two eras, representing symbolic support for the Dutch colonial hegemony. The appropriation of religious space was a spatial strategy to perpetuate the hegemony in social space. This study concludes that the reproduction of Muslim space represented a moderate position towards the Dutch colonial hegemony. Meanwhile, counter-space emerged to reverse such moderating practices. By counter-space, the Dutch moderating efforts on socio-religious space were contested, opposed, and condemned.[Kajian ini berupaya menguraikan secara historis akar Islam moderat, dengan fokus pada praktik produksi ruang keagamaan pada masa penjajahan Belanda di Indonesia. Analisis difokuskan pada perubahan strategi pemerintah kolonial Belanda dalam melakukan reproduksi ruang keagamaan selama periode Perang Aceh dan Sarekat Islam. Pemerintah Belanda sering merebut ruang keagamaan umat Islam untuk mengamankan kekuasaannya. Pemerintah kolonial mereproduksi ruang keagamaan umat Islam pada dua era tersebut sebagai merupakan simbol dukungan terhadap hegemoni kolonial Belanda. Perampasan ruang keagamaan merupakan strategi spasial untuk melanggengkan hegemoni atas ruang sosial. Kajian ini menyimpulkan bahwa reproduksi ruang keagamaan Islam merepresentasikan posisi moderat terhadap hegemoni kolonial. Sementara itu, ruang perlawanan muncul untuk membalikkan praktik-praktik moderasi tersebut. Melalui ruang perlawanan ini, upaya-upaya moderasi pemerintah kolonial Belanda dalam bidang sosial-keagamaan ditentang, ditantang, dan dikecam.]
Acceptability of the Quran Translation
Authors: Al Farisi Mohamad Zaka
Published: March 2024

Muslims have regarded the translation of the Quran into languages other than Arabic as valuable since its benefits for non-Arabic speakers to understand the its messages. However, those translations are not a substitute for the original Arabic Quran, and reciting the Quran in Arabic is not the same as reading its translation. Linguistically, translation is a dual act of interlingual communication that involves the source language (SL), target language (TL), and translator as the main actor. The translator is in charge of presenting the acceptable equivalence of the SL text and the TL text, either on the levels of form, meaning, or intent. Therefore, the acceptability of the translation of Quranic verses is not related merely to their forms and meanings but also to the intended purpose of the text of the SL. In practice, the acceptability of translations can be realized, among other things, by applying appropriate translation techniques and procedures when handling micro-translation units, whether on word, phrase, clause, or sentence levels. In this regard, the acceptability of the Quran translation necessitates the fulfilment of the aspects of accuracy, clarity, naturalness, and relevance. These aspects will bring an acceptability model for a Quranic translation that considered complete and representative. This model stems from the view that translation is not merely seen from the point of communication theory of the code but also from the point of communication theory of inference model. [Umat Islam melihat terjemahan Al-Quran ke dalam bahasa selain bahasa Arab sebagai sesuatu yang berharga karena manfaatnya bagi penutur non-Arab untuk memahami pesan-pesannya. Namun, terjemahan tersebut sejajar dengan Al-Quran yang berbahasa Arab, sehingga membaca Al-Quran dalam bahasa Arab tidak dianggap sama dengan membaca terjemahnya. Secara linguistik, penerjemahan merupakan suatu tindakan komunikasi ganda antarbahasa yang melibatkan bahasa sumber (SL), bahasa sasaran (TL), dan penerjemah sebagai pelaku utama. Penerjemah bertugas menyajikan padanan teks SL dan teks TL yang dapat diterima, baik dalam tataran bentuk, makna, maupun maksudnya. Oleh karena itu, keterterimaan terjemahan ayat-ayat Al-Quran tidak semata-mata berkaitan dengan bentuk dan maknanya, tetapi juga dengan maksud teks tersebut. Dalam praktiknya, keterterimaan terjemah dapat diupayakan antara lain dengan menerapkan teknik dan prosedur penerjemahan yang tepat terkait dengan satuan terjemahan mikro, baik pada tataran kata, frasa, klausa, maupun kalimat. Dalam kaitan ini, akseptabilitas terjemah Al-Quran memerlukan pemenuhan aspek akurasi, kejelasan, kealamian, dan relevansi. Aspek-aspek tersebut akan melahirkan suatu model akseptabilitas suatu terjemah Al-Quran yang dapat dianggap lengkap dan representatif. Model seperti ini berdasarkan pada pandangan bahwa penerjemahan tidak hanya dilihat dari sudut teori komunikasi tentang kode tetapi juga dari sudut teori komunikasi tentang inferensi.]
Struggling for Recognition: Archived-based Documentary Film of the Ahmadiyya Jamaat in Indonesia
Authors: Wulandari Peny , Bawono Harry
Published: March 2024

The Ahmadiyya community has become a victim of persecution as labelled abnormal by other Muslim communities in Indonesia, especially in post-2004. Responding to the issue, the Ahmadiyya community constructs three colours of discourse, religious, humanitarian, and nationalism, to “normalise” their position in Indonesian society. The religious discourse stems from their direct citation to religious texts that confirm their legitimate standpoint. The humanity discourse arises from their action in the humanity program, such as blood and corneal donors. Meanwhile, the nationalism discourse appears in their short archives-based documentary film. This article examines the discourse of nationalism constructed by the Ahmadiyya via a short archives-based documentary film entitled, “Kiprah Ahmadiyah dalam Perjuangan Kemerdekaan Indonesia (the Ahmadiyya’s Role in the Struggle for the Independence of Indonesia)” using Van Dijk discourse analysis frame through an archival studies perspective. This research argues that the nationalism discourse portrayed in the film represents a deliberate act of archival activism planned by the Ahmadiyya community to seek recognition from diverse communities in Indonesia, including mainstream Muslims, general populations, and the state. [Komunitas Ahmadiyah di Indonesia telah menjadi korban persekusi karena label “tidak normal” yang disematkan oleh komunitas Muslim lain di Indonesia, terutama pasca-2004. Merespons isu tersebut, komunitas Ahmadiyah membangun tiga warna wacana: agama, kemanusiaan, dan nasionalisme. Wacana-wacana ini mereka bangun untuk “menormalkan” posisi mereka di tengah masyarakat. Wacana keagamaan dapat diidentifikasi dalam cara mereka mengutip teks-teks agama untuk mengkonfirmasi keabsahan keberadaan dan titik pijak mereka. Wacana kemanusiaan muncul dalam kegiatan mereka dalam program kemanusiaan, seperti donor darah dan kornea. Sementara, wacana nasionalisme dapat dianalisis dalam sebuah film dokumenter pendek. Artikel ini mengkaji wacana nasionalisme yang di konstruksi oleh Ahmadiyah melalui sebuah film dokumenter pendek berbasis arsip berjudul “Kiprah Ahmadiyah dalam Perjuangan Kemerdekaan Indonesia” dengan menggunakan kerangka analisis wacana Van Dijk dalam perspektif studi arsip. Penelitian ini berargumen bahwa wacana nasionalisme yang dibuat dalam film tersebut mencerminkan tindakan aktivisme-kearsipan yang direncanakan oleh komunitas Ahmadiyah untuk memperjuangkan rekognisi dari komunitas lain di Indonesia: Muslim arus utama, komunitas lain secara umum, dan negara.]
The Approach of Imam Abdul Hamid ibn Badis to Sufi Methods
Authors: Omrani Belkheir Ahmed
Published: March 2024

This research is about Shaikh Abdul Hamid ibn Badis, the president of the Algerian Association of Muslim Scholars, who led the reformist movement during the French occupation and was one of the leaders of reformation in the Muslim world. The research aims to reveal how the Shaikh dealt with the reality of Sufism and its spiritual authority and broad influence embedded in Algerian society. The author addresses issues within Algerian society during the French occupation, the position of the Shaikh as a man of satire in general, and his relationship with the elders’ zawaya of Sufi methods. The research concludes that the Shaikh followed a middle ground in his dealings. He was clear in his opinions and convictions and expressed them through his writings and articles, while he had good connections with all the elders’ methods. His approach was not to differentiate but to assemble and remove the differences that weakened the society’s resistance towards the French occupation. As the Imam had been wise and advocative, he knew how to win the hearts and attitudes of his society.[Tulisan ini membahas Syaikh Abdul Hamid ibn Badis, Pemimpin Asosiasi Ulama Muslim Aljazair, yang memimpin gerakan reformis pada masa pendudukan Perancis dan merupakan salah satu pemimpin reformasi di dunia Muslim. Penelitian ini bertujuan untuk mengungkap bagaimana sang Syaikh menyikapi realitas Tarekat serta otoritas spiritual dan pengaruhnya yang luas, yang tertanam dalam masyarakat Aljazair. Penulis membahas isu-isu yang terjadi di tengah masyarakat Aljazair selama pendudukan Perancis, posisi sang Syaikh sebagai satir secara umum, dan hubungannya dengan zawiyah-zawiyah Tarekat yang lebih tua. Penelitian ini menyimpulkan bahwa Ibn Badis telah memilih jalan tengah. Pendapat dan keyakinannya jelas, dia mengungkapkannya melalui tulisan dan artikelnya, sementara hubungannya dengan semua zawiyah Tarekat dibina sangat baik. Pendekatannya bukan untuk membeda-bedakan tetapi untuk mengumpulkan dan menghilangkan perbedaan-perbedaan yang melemahkan perlawanan masyarakat terhadap pendudukan Perancis. Karena sang Imam adalah orang yang bijaksana dan advokatif, dia tahu bagaimana memenangkan hati dan sikap masyarakatnya.]
Novel Mutation (T273R) in Thyroid Hormone Receptor β Gene Provides Further Insight into Cryptic Negative Regulation by Thyroid Hormone
Authors: Kaššák Filip , Hána V. , Saudek V. , Kostrouchová M.
Published: March 2024

Production of thyroid hormone is precisely regulated in a negative feed-back mechanism that depends critically on thyroid hormone receptor β (TRβ). This mechanism decreases production of thyrotropin- releasing hormone (TRH) and thyrotropin (TSH) in the hypothalamus and pituitary gland in response to high levels of circulating thyroid hormones (TH). Despite the wealth of accumulated knowledge, it is still not clear how exactly this negative regulation is executed. The syndrome of resistance to thyroid hormone (RTH), in which the levels of TH are not properly sensed, represents naturally occurring situations in which molecular components of this regulation are displayed and may be uncovered. TRβ, which is central to this regulation, is in the majority of RTH cases mutated in a way that preserves some functions of the receptor. Approximately 150 different mutations in TRβ have been identified to date. Here, we hypothesized that additional pathogenic mutations in TRβ are likely to exist in human population and analysed clinical cases with suspected RTH. In keeping with our prediction, analysis of 17 patients from nine families led to identification of four presumed pathogenic mutations of TRβ, including a previously unknown mutation, T273R. This suggests that threonine 273 is likely to be critical for the normal function of TRβ, possibly due to its role in helix 12 mobility and interaction with coactivators, and thus supports the concept that TRβ-dependent trans-activating function is necessary for the inhibition of TRH and TSH expression in response to elevated levels of TH.
Influence of Cytochrome P450, ABC and SLC Gene Polymorphisms on Imatinib Therapy Outcome of Patients with Gastrointestinal Stromal Tumours (GIST)
Authors: Wasielewski Kacper , Wasag B. , Wozniak A. , Pikiel J. , Kowalik A. , Osuch C. , Bylina E. , Siedlecki J. A. , Rutkowski P. , Limon J.
Published: March 2024

The efficacy of imatinib-based therapy depends on the proteins involved in its metabolism and transportation. Therefore, the aim of our study was to investigate the possible correlation of selected P450, ABC and SLC polymorphic variants and the outcome of imatinib therapy. A total of 101 patients with advanced, KIT/PDGFRA(+) GIST treated with imatinib were enrolled to the study. DNA was extracted from peripheral blood samples and genotypes were determined by PCR-RFLP and direct sequencing. Deviation from the Hardy-Weinberg equilibrium was only observed for rs2740574. None of the studied SNPs was associated with GIST time to progression. No significant correlation between any specific variant and time to progression was found in the group with KIT exon 11 mutation. However, individuals of at least three potentially unfavourable genotypes presented significantly shorter time to progression in comparison to patients with two or less unfavourable genotypes.
Application of SDN-IP hybrid network multicast architecture in Commercial Aerospace Data Center
Authors: Gang Chen , Guangyu Chen , Xin Tong , Qiaoyan Ren , Dongmei Kuang
Published: March 2024

The increasing amount of massive data generated by commercial spacecraft in orbit puts forward higher and higher requirements for the stability, reliability, and computing power of computer systems for commercial aerospace data center. Data center computer systems are gradually transforming from X86 architecture and IP network model to a platform model with cloud computing and software-defined network (SDN) technology. This article proposes a new network architecture based on a unicast/multicast protocol for data interaction between the SDN and IP network. There are three main contributions of this article. The first is that the architecture proposed in this article aims to reduce end-to-end transmission latency and packet loss. The second is to improve the flexibility of system configuration and precise control when the SND controller state changes. The third is to verify the feasibility of deploying network architecture in a real data center environment.
Evaluation of the impact of two citrus plants on the variation of Panonychus citri (Acari: Tetranychidae) and beneficial phytoseiid mites
Authors: Assouguem Amine , Joutei Abdelmalek Boutaleb , Lahlali Rachid , Kara Mohammed , Bari Ahmed , Ali Essam A. , Fidan Hafize , Laabidine Hajar Zine , El Ouati Younouss , Farah Abdellah , Lazraq Abderrahim
Published: March 2024

The abundance of Panonychus citri McGregor 1916 (Acari: Tetranychidae) and its associated enemies (Euseius stipulatus Athias-Henriot, 1960; Typhlodromus sp.; Phytoseiulus persimilis Athias-Henriot, 1957) was studied on two 12-year-old citrus cultivars, specifically Clementine “Nules” (Citrus Clementina) and Valencia (Citrus sinensis), in the Gharb region of Morocco. Throughout the entire monitoring period in the Valencia late cultivar, the density of the spider mite P. citri on leaves was notably higher at 38.0% (n = 1,212 mobile forms). Predator P. persimilis exhibited a leaf occupancy of 25.0% (n = 812), followed by Typhlodromus sp. at 20.0% (n = 643). Conversely, the abundance of E. stipulatus was lower at 17.0% (n = 538). In the Nules variety, P. citri abundance recorded a higher percentage at 48.0% (n = 1,922). E. stipulatus emerged as the most abundant predator at 23.0% (n = 898), followed by P. persimilis with 16.0% (n = 639). Meanwhile, the population of Typlodromus sp. remained notably low at 13.0% (n = 498). Regarding the fluctuation of the different mites studied on the two cultivars across monitoring dates, the period from May 4 to June 1 was characterized by low temperatures and a diminished presence of mite populations (P. citri, E. stipulatus, Typhlodromus sp., and P. persimilis). However, from June 7 to June 19, characterized by high temperatures, a notable increase in the presence of mite populations was observed. As regards the effect of the variety on the different mites studied, the varietal impact was significant.
Transfer of collostructions: the case of causative constructions
Authors: Gilquin Gaëtanelle
Published: March 2024

In an attempt to identify possible cases of collostructional transfer in the use of the causative construction [X
make
Y Vinf] by French-speaking learners of English, two types of analyses are combined in this study. First, a contrastive collostructional analysis compares the verbs occurring in the [Vinf] slot of the English construction and its French equivalent, [X
faire
Vinf Y]. Second, a contrastive interlanguage collostructional analysis compares the verbs used in the [Vinf] slot of [X 
make
Y Vinf] by native speakers of English, French-speaking learners of English and learners of English from other mother tongue backgrounds. The aim is to identify verbs that are more distinctive of [X
faire
Vinf Y] than of [X
make
Y Vinf] and that are also more likely to be used by French-speaking learners of English than by other populations, as these verbs could be potential cases of collostructional preferences transferred by learners from French to English. The results suggest that learners might transfer verbs expressing a change of state or location and some individual verbs like discover from the French to the English causative construction. Their dispreference for copular verbs (other than be) could also be the result of transfer effects.
Radiofrequency thermal ablation of giant placental chorioangioma complicated with fetal hydrops: a case report and successful outcome
Authors: Le Vance Jack , Gurney Leo , Meher Shireen , Negrine Robert , Hodgetts Morton Victoria , Marton Tamas , Morris R. Katie
Published: March 2024

Objectives

Chorioangiomas are the most frequently occurring type of benign tumour of the placenta. However, large chorioangiomas greater than 4 cm are rare and can be more frequently associated with serious complications such as: polyhydramnios, hydrops fetalis, fetal anaemia, intrauterine growth restriction, preterm birth, and an increased risk of perinatal mortality. Importantly timely prenatal diagnosis with close surveillance alongside potential intrauterine intervention can prove impactful on pregnancy outcome and fetal survival.

Case presentation

We present a case of a 36-year-old female referred to our tertiary fetal medicine unit at 28 weeks’ gestation with a large chorioangioma measuring 9.4×8.8×5.5 cm and ultrasonographic evidence of severe fetal anaemia and fetal hydrops. The patient underwent an intrauterine transfusion and in utero surgical therapy with radiofrequency ablation (RFA). Immediately following the procedure, the fetus sustained a period of bradycardia, followed by asystole. Delivery was expedited via emergency caesarean section. Careful planning and rapid delivery after fetal intervention within the most appropriate surgical setting mitigated risks for the baby and resulted in a positive outcome. The baby was discharged from the neonatal unit on day 84 of life.

Conclusions

Large placental chorioangiomas are a rare occurrence, however, when associated with fetal complications present a high incidence of adverse perinatal outcomes. In utero interventions require careful planning and surgical expertise to ensure improved fetal and neonatal outcomes. To the best of our knowledge this case is the first recorded instance of a successful postnatal outcome following RFA for a large placental chorioangioma, whereby the fetus was complicated by fetal hydrops.
Simultaneous estimation of ibuprofen, caffeine, and paracetamol in commercial products using a green reverse-phase HPTLC method
Authors: Alqarni Mohammed Hamed , Shakeel Faiyaz , Alshehri Sultan , Foudah Ahmed Ibrahim , Aljarba Tariq Mohammed , Abdel Bar Fatma Mohamed , Alam Prawez
Published: March 2024

A fast, sensitive, and green reverse-phase “high-performance thin-layer chromatography” approach for the simultaneous estimation of ibuprofen (IBF), caffeine (CAF), and paracetamol (PCM) in marketed formulations was established and verified in this study. The binary combination of acetone and water (80:20 v/v) was used as the green eluent system. The current method’s greenness was predicted using four different approaches, namely National Environmental Method Index, Analytical Eco-Score (89), ChlorTox (1.08 g), and the Analytical GREENness (83) approaches, which demonstrated an outstanding greener profile. The present approach was linear in the range of 25–800 ng·band−1 for the simultaneous estimation of IBF, CAF, and PCM. In addition, the current method was accurate (% recoveries = 100 ± 2), precise (%CV < 2%), robust (%CV < 2), sensitive (LOD = 1.13–2.71 ng·band−1 and LOQ = 3.39–8.10 ng·band−1), and green. The amount of IBF, CAF, and PCM in commercial tablets was determined to be 99.51%, 98.25%, and 100.64%, respectively. The present method for the simultaneous determination of IBF, CAF, and PCM in marketed tablets is supported by these data. The findings of this study suggested that the current approach may be consistently applied to analyze IBF, CAF, and PCM in marketed tablets.
Hybrid work – a reconceptualisation and research agenda
Authors: Richter Alexander , Richter Shahper
Published: March 2024

We begin this conceptual paper, by outlining three recent developments in the context of the changing the nature of work: (1) the increasing proportion of remote work, (2) the quickly expanding use of (generative) AI applications, and (3) the growing advancements in virtual world technologies and platforms. We argue that the synthesis of these developments will vastly impact traditional work models and practices. This transformation warrants a critical rethinking of the traditional understanding of hybrid work which, so far, has predominantly focused on the spectrum of in-person and remote work. We suggest adjusting this perspective and posit grand challenges and related research questions in order to do so.
Effect of synthesis method on structural and magnetic properties of La0.7Ca0.2Ba0.1MnO3
Authors: Nastar-Córdoba Valeria , Guerrero Alejandra I. , Villaquiran-Raigoza Claudia , Ramírez Alfonso , Tirado Liliana , Gaona-Jurado Sonia
Published: March 2024

We study the effect of the synthesis method on the structural and magnetic properties of La0.7Ca0.2Ba0.1Mn03. The samples were synthesized by coprecipitation and solution combustion methods. X-ray diffraction and scanning electron microscopy were performed to investigate the crystallographic structure, showing that both methods produced La0.7Ca0.2Ba0.1Mn03 monophasic samples. From magnetization measurements a second-order, ferromagnetic to paramagnetic, phase transition was observed. The Curie temperature is found to be 272 K for the sample obtained by coprecipitation and 283 K for the sample obtained by solution combustion. There is a small magnetic hysteresis for both samples. The magnetocaloric parameters were obtained using a phenomenological model; the magnetic entropy change and relative cooling power factor are higher in the sample synthesized by combustion.
Filling the gap of distribution of the pale-winged dog-like bat Peropteryx pallidoptera (Chiroptera, Emballonuridae) in Brazil and Peru
Authors: Santos Tamily C.M. , Lopes Gerson P. , Novaes Roberto Leonan M. , Cláudio Vinícius C. , Valsecchi João , Hirota Andrezza S.V. , Martínez-Fonseca José G. , Marcos Marcelo H. , Kuniy Adriana A. , Clara do Nascimento Maria
Published: March 2024

Peropteryx pallidoptera is the newest described species of Peropteryx, know from only few localities in Ecuador, Peru, Brazil, Colombia, and Bolivia. Herein, we report new records of this species, and we show that P. pallidoptera has a wider distribution than known across the Amazon. Our records are based on field sampling and, mostly, on museum vouchers, which reinforces the importance of biological collections and the need to continually review deposited specimens.
Construction of 4 x 4 symmetric stochastic matrices with given spectra
Authors: Jung Jaewon , Kim Donggyun
Published: March 2024

The symmetric stochastic inverse eigenvalue problem (SSIEP) asks which lists of real numbers occur as the spectra of symmetric stochastic matrices. When the cardinality of a list is 4, Kaddoura and Mourad provided a sufficient condition for SSIEP by a mapping and convexity technique. They also conjectured that the sufficient condition is the necessary condition. This study presents the same sufficient condition for SSIEP, but we do it in terms of the list elements. In this way, we provide a different but more straightforward construction of symmetric stochastic matrices for SSIEP compared to those of Kaddoura and Mourad.
CD36-mediated podocyte lipotoxicity promotes foot process effacement
Authors: Hua Wei , Peng Lan , Chen Xue-mei , Jiang XuShun , Hu JianGuo , Jiang Xian-Hong , Xiang Xu , Wan Jiangmin , Long Yingfei , Xiong Jianqiong , Ma Xueyi , Du Xiaogang
Published: March 2024

Background

Lipid metabolism disorders lead to lipotoxicity. The hyperlipidemia-induced early stage of renal injury mainly manifests as podocyte damage. CD36 mediates fatty acid uptake and the subsequent accumulation of toxic lipid metabolites, resulting in podocyte lipotoxicity.

Methods

Male Sprague-Dawley rats were divided into two groups: the normal control group and the high-fat diet group (HFD). Podocytes were cultured and treated with palmitic acid (PA) and sulfo-N-succinimidyl oleate (SSO). Protein expression was measured by immunofluorescence and western blot analysis. Boron-dipyrromethene staining and Oil Red O staining was used to analyze fatty acid accumulation.

Results

Podocyte foot process (FP) effacement and marked proteinuria occurred in the HFD group. CD36 protein expression was upregulated in the HFD group and in PA-treated podocytes. PA-treated podocytes showed increased fatty acid accumulation, reactive oxygen species (ROS) production, and actin cytoskeleton rearrangement. However, pretreatment with the CD36 inhibitor SSO decreased lipid accumulation and ROS production and alleviated actin cytoskeleton rearrangement in podocytes. The antioxidant N-acetylcysteine suppressed PA-induced podocyte FP effacement and ROS generation.

Conclusions

CD36 participated in fatty acid-induced FP effacement in podocytes via oxidative stress, and CD36 inhibitors may be helpful for early treatment of kidney injury.
Operational wear behaviour of 3D-printed lightweight metal gears: EDS and oil analysis comparison
Authors: Tezel Tugce , Schultheiss Ulrich , Hornberger Helga , Kovan Volkan
Published: March 2024

Additive manufacturing (AM) has come to the fore in recent years among manufacturing techniques. This technique, which has different advantages than traditional ones such as casting, forging and machining, is expected to be widely used in producing machine parts like gears in the coming years. Therefore, experimental data on AM parameters for lightweight metal gears are important for industrial production. In this study, a wear test was applied to AlSi10Mg and Ti6Al4V gears under operational conditions, and the wear behaviour of conventionally and additively manufactured gears was compared. The amount of abrasion elements was determined by analysing the oil in the gearbox. In addition, gear surfaces were analysed using scanning electron microscopy and an energy-dispersive spectrometer before and after wear. Thus, the wear behaviour of gears produced by conventional and AM under service conditions was demonstrated comparatively.
Exfoliation behavior of EN AW 7020 with T6, step aging and ultrasonic impact peening processes
Authors: Yurdgülü Halil Ibrahim , Sadeler Recep , Koç Barış
Published: March 2024

In this study the effect of T6 heat treatment, two-step aging treatment and ultrasonic impact peening on the exfoliation corrosion behavior of welded EN AW 7020 was investigated. Exfoliation tests were performed according to the ASTM G34-01 standard. As expected, as a result of the tests, the base material region of all three samples were showed better corrosion resistance than the heat-affected region. Ultrasonic impact peening and two-step aging treatment was observed that improved EXCO sensitivity in the weld area. When sorting was made by considering the resistance to corrosion of the heat affected zone of the samples, it was observed that the best resistance was shown by the sample with two-step aging treatment, and the worst resistance was shown by the sample with T6 heat treatment.
Using nano-CaCO3 and ceramic tile waste to design low-carbon ultra high performance concrete
Authors: Zhang Liqing , Bian Mingqiang , Xiao Zhenrong , Wang Yunyang , Xu Kaicheng , Han Baoguo , Huang Hong
Published: March 2024

China’s annual production of ceramic tiles inevitably produces a large amount of ceramic tile waste, which causes environmental and land occupation problems. Using a high-volume ceramic tile waste to fabricate ultra high performance concrete (UHPC) will reduce the workability and mechanical properties but increase the low-carbon properties. Motivated by such mechanical and low-carbon properties, this study introduced inexpensive, spherical, low-carbon nano-CaCO3 (NC) to improve the workability and mechanical properties of UHPC with a high volume of ceramic tile waste powder and aggregate (UHPCHCTWPA). The results of this study indicated that NC can improve the workability but shortened the setting times of UHPCHCTWPA. NC also significantly increases the mechanical properties including compressive strength, compressive work, flexural strength, fracture energy, and ratio of flexural strength to compressive strength. It is due to that NC enhances the hydration rate and hydration degree, and optimizes hydration product orientation, size, and distribution. Moreover, compared with UHPC, the UHPCHCTWPA with NC reduces energy intensity, CO2 emission, and cost by more than 20%. Therefore, adding NC can make UHPCHCTWPA with good workability, mechanical and low-carbon properties and can effectively and quickly utilize ceramic tile waste.
How to optimize the immune checkpoint blockade therapy for cancers?
Authors: Guo Hui , Hou Yuchuan , Wang Chunxi , Ding Jianxun
Published: March 2024

The realm of cancer therapy has been profoundly altered with the emergence of immune checkpoint blockade (ICB) therapy, providing improved survival prospects for many patients with some cancers. However, the challenge of achieving efficient or sustained therapeutic benefits underscores the critical imperative to optimize ICB strategies. This review elucidates the pivotal role of predictive biomarkers in optimizing precision ICB therapy, deciphering the intricate dynamics associated with the response heterogeneity. Furthermore, it critically examines the application of nanotechnology-driven drug delivery as a promising avenue to amplify ICB efficacy, facilitating controlled and targeted drug release. Recognizing the comprehensive and dynamic interplay among tumor cells, immune cells, and stromal cells has catalyzed the transformative advances in reverse translational research. This approach enables researchers to gain insights into the underlying mechanisms of ICB therapy, therapeutic responses, and resistance mechanisms. The convergence of predictive biomarkers, revolutionary nanotechnology, and reverse translational research emerges as an indispensable focal point, propelling the frontiers of precision oncology within the complex landscape of ICB therapy.
Environmental Regulation Intensity and Low-Carbon Technology Progress in the Context of the Internet of Things
Authors: Lin Lin , Lan Wei
Published: March 2024

Whether the intensity of environmental regulation affects the progress of low-carbon technology is an important issue faced by the development of low-carbon economy in the new era. From a macro perspective, this article selects panel data from 30 provincial-level administrative regions in China from 2000 to 2009 for analysis. The impact and mechanism of environmental regulation intensity on low-carbon technological progress are analyzed. The empirical results indicate that the increase in environmental regulation intensity has significantly promoted the progress of low-carbon technology in the region. The subsample test shows that this effect is greater in the eastern region than in the central and western regions, but there is no significant difference in the impact of environmental regulatory intensity on the progress of the two types of low-carbon technologies. The mechanism test shows that regional labor costs research and development capabilities have moderating effects on the above effects. These low-carbon technologies have been widely applied in various fields of the Internet of Things.
Impact of two physical exercise social programs on seniors fall risk
Authors: Alves Camelo Janaína , Porto Flávia , Assumpção Harris Elizabeth Rose , Da Penha Santos Cintia , Lima da Silva Nádia Souza
Published: March 2024

The aim of this study was to compare the impact of physical exercise on the risk of falls in older adults participating in two social programs. Thirty volunteers participated, divided into two groups: Con Burden (GCC), with 11 women and 4 men (75.4±9.1 years) participating in a university extension project, and Sem Carga (GSC), with 12 women and 3 men (66.9±4.2 years) who exercised at an outdoor gym in the same geographic region. GCCs and GSCs were similar in terms of female predominance, while GCCs are longer-lived (p=0.008). Every participant underwent physical-functional assessment with the Berg Balance Scale. The difference between groups was assessed using the Mann-Whitney test (p ≤ 0.05). Data analysis found no significant difference between the groups regarding the results of the MSA (p=0.2) and both groups had a low risk of falling.
The Physical Properties of Paper in Relation to its Micro- and Macrostructure – Prepared Contribution
Authors:   Institut National Polytechnique de Grenoble, Silvy J.
Published: March 2024

The properties of paper are defined on two sampling scales, depending on whether the micro- or the macroscopic physical characteristics of the sheet are of interest. Two models are presented for the structure of homogenized paper, based either on the orientational distribution of the fibres or on that of the interfaces of pores and fibres. Orientational anisotropy arises on the scale of the fibre aggregates through shearing between flocs. Accurate tests were performed of the floc anisotropy, which influences the properties of paper on the size scale of a few mm2.
Comments on the Effects of Chaos on “Controllability”
Authors:   Department of Paper Science, UMIST, Kropholler Hein W. , Guesalaga Andres R. ,   Department of Paper Science, UMIST
Published: March 2024

Below are appended some general comments on SESSION 8 “CONTROLLABILITY”, and some implications for the development of control systems, with particular reference to the phenomenon of chaos. There are many interesting aspects and the examples of process modelling and identification in the papers of this session. The complexity of the papermaking process and hence the requirements of an effective control system are very clearly illustrated. There is a vast useful literature on control theory and applications. The total process performance and its profitability must determine the role of the control system. The subject can be presented as a series of facets developed in an orderly manner. First there are some basic theoretical definitions such as controllability (in its specialised technical meaning), observability, sampled data systems, instability and chaos. After that, there is the process performance which needs to be considered: as a design or static system; as a dynamic operating system; and quality assurance. It is also important to encompass mill wide performance.