bluuebunny/crossref_metadata_2025 huggingface dataset:
Efficient power management unit for IIOT edge computing applications
Authors: Mukul Mukul Sharma , Shiv Shiv Kumar , Rashmi Rashmi Chawla
Published: August 2021

Applications of Industrial Internet of Things (IIoT) are comprehended in mass domains, and this reflects the prominence of IoT. However, the main con of IoT applications is that it requires continuous power to be drawn by various components to operate all the time. Energy harvesting provides a potential solution to this problem in many applications; however, this continual energy usage remains main IoT con. The energy generated by ambient sources is inadequate to run system application, and a need for better Power Management Unit (PMU) persists. This research paper proposes a PMU framework for energy efficiency in edge computing application with three layers of IoT architecture. Design-build on this deployment, constitutes sleep and awake scheduling, with calculative idle intervals. The transitions of states exercise an energy-efficient solution for the entire system. The design is tested on ZYBO Zynq-7000 (XC7Z010-1CLG400C) ARM/FPGA SoC board for development and evaluation. Simulation results demonstrate the task scheduling of our proposed architecture and energy consumption details. In brief, the proposed design proves to be a beneficial option, in particular, surpassing kin designs for industrial automation.
Rapid Visualization and Detection of Staphylococcus Aureus Based on Loop-Mediated Isothermal Amplification
Authors: Wu Chuan , Zeng Yuanyuan , He Yang
Published: August 2021

Staphylococcus aureus is a common clinical bacterial pathogen that can cause a diverse range of infections. The establishment of a rapid and reliable assay for the early diagnosis and detection of S. aureus is of great significance. In this study, we developed a closed-tube loop-mediated isothermal amplification (LAMP) assay for the visual detection of S. aureus using the colorimetric indicator hydroxy naphthol blue (HNB). The LAMP reaction was optimized by adjusting the amplification temperature, the concentrations of Mg2+, dNTP, and HNB, and the incubation time. In the optimized reaction system, the specificity of LAMP for S. aureus was 100%. The results established that this method accurately identified S. aureus, with no cross-reactivity with 16 non-S. aureus strains. The limit of detection (LOD) of LAMP was 8 copies/reaction of purified plasmid DNA or 400 colony-forming units/reaction of S. aureus. Compared with conventional PCR, LAMP lowered the LOD by 10-fold. Finally, 220 clinically isolated strains of S. aureus and 149 non-S. aureus strains were used to evaluate the diagnostic efficacy of LAMP. The findings indicated that LAMP is a reliable test for S. aureus and could be a promising tool for the rapid diagnosis of S. aureus infections.
Factors Contributing To The Swimmer Puppy Syndrome Found in Labrador Retrievers
Authors: TOMIHARI Mizuki , NOBUTOKI Yuko , NAKAJIMA Nagachika , YANAGAWA Masashi , TAGAWA Michihito , HAGIYA Koichi , NOMURA Tetsuro , SUWA Yoshinori , SUZUKI Hiroshi
Published: August 2021

Background
Swimmer puppy syndrome is a disease found in neonatal puppies mainly characterized by the inability to stand, but its direct cause is unknown. Since swimmer puppies were observed infrequently but continuously among the Labrador retriever colony at the Hokkaido Guide Dogs for the Blind Association in Japan, based on their birth record and pedigree, factors related to the onset of swimmer puppy syndrome in Labrador retrievers were examined.
Results
The total number of offspring over seven years was 436, of which 16 were swimmer puppies. Most of the affected puppies except one recovered steadily. As for the swimmer puppies, the litter size was significantly lower, and the body weights on the 10th and 28th day after delivery were significantly higher than the non-symptomatic puppies. These results suggested that the onset may be related to weight gain in the neonatal stages due to a small litter size. According to the genetic analysis, 26 ancestors common to the affected individuals were confirmed, but the causative individual could not be identified with the inbreeding coefficient. The heritability of the swimmer-puppy onset trait was 0.80, and the heritability for the the 10th -day body-weight trait was equally high at 0.78, both of which strongly suggest genetic involvement.
Conclusions
In this study, the onset of swimmer puppy syndrome in the Labrador retrievers was associated with litter size and early weight gain, and result of study suggests that genetic influence might be involved.
Effect of Inverted Internal Limiting Membrane Flap Technique on Normal Size Macular Holes
Authors: Yamada Kanako , Oishi Akio , Kusano Mao , Kinoshita Hirofumi , Tsuiki Eiko , Kitaoka Takashi
Published: August 2021

Inverted internal limiting membrane (ILM) flap technique was developed to achieve macular hole (MH) closure in large MH and refractory cases. In this study, we evaluate the effect of the technique for normal size MH. We recruited patients who underwent vitrectomy for normal size (< 400 µm) MH with either inverted ILM flap technique (flap group) or with conventional ILM peeling (peeling group). Using propensity score,21 eyes of 21 patients in the peeling group were matched against 21 eyes of 21 patients in the flap group. we compared MH closure rate, postoperative visual acuity, and recovery of the external limiting membrane (ELM) and ellipsoid zone (EZ). The MH closure rate was not different between the two groups (flap vs peeling: 90% vs 100%, P = 0.49). Whereas there was no significant difference in visual acuity improvement between the two groups, the flap group showed more disruption of the ELM 3 months after surgery and of the EZ at 3 and 6 months after surgery (P = 0.02, P = 0.03, and P = 0.04, respectively). The result suggested that inverted ILM flap technique does not have additional benefits for normal size MHs and may delay recovery of retinal integrity.
The correlation between type 2 diabetes and fat fraction in liver and pancreas: a study using MR Dixon technique
Authors: Shun Yu , Jieqin lv , zhongshuai Zhang , Mingping Ma , Jiawei Su
Published: August 2021

Background

The increased obesity results in ectopic fat deposits in liver and pancreas.Ectopic fat deposits affect insulin resistance and blood sugar content with Type 2 Diabetes.To assess the relationship between obesity and ectopic fat deposits and diabetes,this study used MR Dixon method for the quantification of liver and pancreas fat fraction (FF) in T2DM patients and healthy controls.
Methods

The FF of liver and pancreas, the maximum diameters of the pancreas, SAT, VAT and TAT were measured for 167 subjects using the MR Dixon data.Four groups were established on the basis of BMI value.For statistics, intra-and inter-group comparison was done by employing Independent Sample t Test.
Results

① The average fat content in liver and pancreas, the fat content in pancreas body and tail, and VAT in Group 1 were higher than those in Group 3 (P༜0.05). ② The average fat content in liver and pancreas, the adipose fraction of the pancreas head, and VAT in the Group 2 were higher than those in Group 4 (P༜0.05). ③ The average fat content of liver and pancreas, the adipose content of the body and the tail of the pancreas, the abdominal subcutaneous adipose area (SAT), the visceral adipose tissue area (VAT), and the total abdominal adipose tissue area (TAT) in Group 2 were higher than those in the Group 1 (P༜0.05). ④ The FF of pancreas tail, SAT and TAT in Group 4 were higher than those in Group 3 (P༜0.05).
Conclusion

The tissue FF,which has a close relationship with T2DM,can be assessed by MR Dixon technique.The results showed that all T2DM patients should pay attention to tissue fat content regardless of BMI values.
Contemporary (2019) prevalence of cardiovascular disease in adults with type 2 diabetes in Brazil: the cross-sectional CAPTURE study
Authors: Vencio Sérgio , Vianna André Gustavo Daher , Silva Mariana Arruda C Ferreira da , Precoma Dalton B
Published: August 2021

BackgroundType 2 diabetes (T2D) is a known risk factor for cardiovascular disease (CVD), and CVD is a major cause of mortality in patients with T2D. The CAPTURE study investigated the contemporary (2019) prevalence of established CVD in adults with T2D around the world. We report the findings from Brazil.MethodsThe multinational, non-interventional, cross-sectional CAPTURE study was conducted across 13 countries from five continents. The current manuscript explores data for the CAPTURE study sample in Brazil. Standardized demographic and clinical data were collected from adults with T2D aged ≥ 18 years attending a single routine healthcare visit in primary or specialized care between December 2018 and September 2019. Data were analyzed descriptively.ResultsData from 912 adults with T2D were collected in the CAPTURE study in Brazil, with 822 patients from primary care and 90 patients from specialized care. Median (interquartile range [IQR]) patient characteristics were as follows: age 64 years (57; 71), diabetes duration 11 years (6; 19), glycated hemoglobin 7.7% (6.7; 9.1), and body mass index 29.5 kg/m2 (26.4; 33.5); 59% were female. The CVD prevalence and atherosclerotic CVD prevalence in the Brazil sample were 43.9% (95% confidence interval [CI] 40.9; 46.8) and 37.6% (95% CI 34.7; 40.5), respectively. The majority of patients with CVD had atherosclerotic CVD (85.8%). For the specific CVD subtypes, coronary heart disease prevalence was 27.9% (95% CI 25.2; 30.5), heart failure was 12.4% (95% CI 10.4; 14.4), cerebrovascular disease was 8.7% (95% CI 6.8; 10.5), and carotid artery disease was 3.4% (95% CI 2.3; 4.5). Glucagon-like peptide-1 receptor agonists and/or sodium-glucose co-transporter-2 inhibitors with proven cardiovascular benefit were prescribed to 15.5% of patients with CVD, compared with 18.4% of patients without CVD.ConclusionsCAPTURE was the first multinational, standardized study to provide contemporary data on CVD prevalence in adults with T2D in Brazil, and it demonstrated that almost one in two adults with T2D had established CVD. Except for carotid artery disease, the prevalence of all CVD subtypes in adults with T2D in Brazil appeared higher than the global CAPTURE prevalence.Trial registration: NCT03786406, NCT03811288.
A Transcription Factor DAF5 Functions in Haemonchus Contortus Development
Authors: Di Wenda , Li Fangfang , He Li , Wang Chunqun , Zhou Caixian , Liu Lu , Ye Lisa , Chen Jian , Hu Min
Published: August 2021

Background: Daf5 (Dauer abnormal formation gene), located in the downstream of DAF-7 signalling pathway, mainly functions in dauer formation and reproductive processes in the free-living nematode Caenorhabditis elegans. Although its structure and function have been studied clearly in C. elegans, it was totally unknown in Haemonchus contortus, a socio-economically important parasitic nematode of gastric ruminants.Methods: Here, we identified and characterized a homologue of Daf5, Hcdaf5 and its inferred product (HcDAF5) in H. contortus. Using an integrated molecular approach, we studied the transcriptional profiles of Hcdaf5 and the anatomical expression of HcDAF5 in H. contortus. RNA interference (RNAi) was performed to explore its function in transition from the exsheathed third-stage larvae (xL3) to the fourth-stage larvae (L4) in vitro. Interaction of HcDAF5 and HcDAF3 (a co-SMAD) was also detected by bimolecular fluorescence complementation system (BiFc) in vitro.Results: Here, we showed that HcDAF5 is a member of the Sno/Ski superfamily. Hcdaf5 was transcribed in all developmental stages of H. contortus, with a significant up-regulation in L3. Immunohistochemistry localized native HcDAF5 to the reproductive organs, cuticle and intestine. RNAi revealed specific siRNAs (small interfering RNA) could retard the xL3 development. In addition, the interaction between HcDAF5 and HcDAF3 indicated the SDS box region of HcDAF5 is dispensable for the binding of HcDAF5 to HcDAF3 and the region in HcDAF3 that binds to HcDAF5 is MH2 domain.Conclusion: In summary, these findings show that Hcdaf5 functions in developmental processes of H. contortus, and this is the first characterization of daf-5 gene in parasitic nematodes.
Climate- and Technology-Specific PUE and WUE Predictions for U.S. Data Centers using a Physics-Based Approach
Authors: Lei Nuoa , Masanet Eric
Published: August 2021

The onsite water use of data centers (DCs) is becoming an increasingly important consideration within the policy and energy analysis communities, but has heretofore been difficult to quantify in macro-level DC energy models due to lack of reported water usage effectiveness (WUE) values by DC operators. This work addresses this important knowledge gap by presenting thermodynamically-compatible power usage effectiveness (PUE) and WUE values for a wide range of U.S. DC archetypes and climate zones, using a physics-based model that is validated with real-world data. Results enable energy analysts to more accurately analyze the onsite energy and water use of DCs by size class, cooling system type, and climate zone under many different operating conditions including operational setpoints. Sensitivity analyses further identify the variables leading to best-achievable PUE and WUE values by climate zone and cooling system type—including operational set points, use of free cooling, and cooling tower equipment and operational factors—which can support DC water- and energy-efficiency policy initiatives. The consistent PUE and WUE values may also be used in future work to quantify the indirect water use of DCs occurring in electrical power generating systems.
Effect of arterial blood bicarbonate (HCO3−) concentration on the accuracy of STOP-Bang questionnaire screening for obstructive sleep apnea
Authors: Pei Chong , Gui Shuyu
Published: August 2021

Background
To evaluate the effect of arterial bicarbonate (HCO3−) concentration on the accuracy of STOP-Bang questionnaire (SBQ) screening for obstructive sleep apnea (OSA).
Methods
A total of 144 patients with suspected OSA were included. Polysomnograms (PSG) and blood gas analysis were performed, and the Epworth Sleepiness Scale (ESS), STOP-Bang questionnaire, and Berlin questionnaire were completed. The correlation between the arterial HCO3− concentration, apnea hypopnea index (AHI), and other related indicators was analyzed. The scoring results of the ESS, SBQ, and Berlin questionnaire were compared with the PSG results, and the sensitivity and specificity were calculated in the form of a four-cell table. The changes in the sensitivity and specificity of OSA screening after SBQ alone and combined with HCO3− concentration were compared, and ROC curves were drawn.
Results
Arterial HCO3− concentration was positively correlated with AHI (r = 0.537, P < 0.001). The ratio of HCO3− concentration ≥ 24.6 mmol/L in the non-OSA group was significantly lower than that in the OSA group (25.0% VS 80.8%, P < 0.001). The sensitivity of the SBQ was higher than that of the ESS (97.5% VS 81.7%, P < 0.001) and the Berlin questionnaire (97.5% VS 79.2%, P < 0.001). There was no statistical significance in the specificity of the three scales (25%, 37.5%, 37.5%). A combined SBQ score ≥ 3 and HCO3− concentration ≥ 24.6 mmol/L showed increased specificity and decreased sensitivity compared with an SBQ score ≥ 3 alone, with a corresponding AUC of 0.771 (P < 0.01) and 0.613 (P > 0.05), respectively.
Conclusion
The sensitivity of the SBQ was better than that of the Berlin questionnaire and ESS. After combining arterial blood HCO3− concentration, the SBQ questionnaire increased the specificity of OSA prediction and decreased the sensitivity, which improved the accuracy of screening.
Growth studies in commercial broiler birds offered citric acid in formulated feed with low mineral density
Authors: Katoch Shivani , Sharma Sumani , Sankhyan Varun , Wadhwa Daisy , Sharma Arun , Upadhyay Sanjiv Kumar
Published: August 2021

A study was conducted to evaluate citric acid (CA) as an additive in poultry broiler diet with lower mineral density of calcium and phosphorus in commercial broiler poultry birds under complete randomized design. For this purpose, Vancobb-400 strain day old broiler chicks (n=320) were divided into 4 main treatment groups T0, T1, T2 and T3. Each treatment group was further divided into8 replicates with 10 chicks in each. T0 served as control diet and was given standard corn- soy flake based ration(Pre-starter%; CP;Ca;TP--23,1.00,0.70, Starter;22,1.10,0.72 and Finisher;20,0.99.70)and treatment T1 served as standard ration with added 0.5 per cent CA with no change in chemical composition (Pre-starter %; CP;Ca;TP23,1.00,0.70, Starter; 22,1.10,0.72 and Finisher;20,0.99.70). Treatment T2 was given standard cornsoy flake based ration containing 0.5 per cent CA with low calcium (Ca) and total phosphorus (TP) content (Pre-starter %; CP;Ca;TP --23,0.90,0.66,Starter; 22,0.99,0.71 and Finisher;20,0.90,0.69)whereas treatment T3 was given standard corn- soy flake based ration containing 0.5 per cent CA with moderately low calcium (Ca) and total phosphorus (TP) content(Pre-starter %;CP;Ca;TP--23,0.80,0.65,Starter;22,0.88,0.70 and Finisher;20,0.79,0.68)as per ICAR (2013) standards. Perusal of the results revealed that broiler birds offered moderately low Ca and TP exhibited higher growth performance (P<0.05) for gain in weight, feed intake, feed conversion efficiency and carcass traits viz. dressing percentage and forequarters weight. Addition of 0.5 per cent CA in low and moderately low Ca and TP offered diets conferred protection to birds by lowering mortality in birds through reduction in total microbial count in the lower gastro intestinal tract. Results of the experiment revealed activation of homeostatic mechanisms in birds offered moderately low Ca and TP with added 0.5% CA modulating enhanced availability of calcium and phosphorus as evident in metabolic trial, blood and tibiae bone studies but the homeostatic mechanism was less pronounced when Ca and TP density in diet was low. Overall economics exhibited lowest cost of producing, per kg live weight in broiler birds offered moderately low Ca and TP with added 0.5 % CA. In conclusion, birds offered corn soya based diet with moderately low mineral viz. calcium and total phosphorus as per ICAR 2013 standard with added 0.5 per cent citric acid can enhance the growth, improve carcass characteristics and improve the FCR of broilers though favourable environment in lower intestinal tract and activation of homeostatic mechanisms of calcium and phosphorus digestion and absorption, thus economizing the cost of production.
Association of Active Coping to Unfair Treatment with Perceived Stress and Depressive Symptoms in African Americans: MH-GRID Study
Authors: Ojebuoboh Ayomide , Gonzalez-Feliciano Amparo , Brown Kristen , Khan Rumana , Xu Ruihua , DeRoo Lisa , Lewis Jessica , Quarells Rakale , Davis Sharon
Published: August 2021

Background: Unfair treatment such as discrimination and racism contribute to depression and perceived stress in African Americans. Although studies have examined how responding to such treatment is associated with ameliorating depressive symptoms and levels of perceived stress, most do not focus on African Americans. The purpose of this study is to assess how talking to others in response to unfair treatment is associated with self-reported depressive symptoms and perceived stress levels in African Americans.Methods: A sample from the 2010-2013 Minority Health Genomics and Translational Research Bio-Repository Database was used and consisted of 376 African American adults aged 30-55 years old residing in the southern region of the United States. Linear regression models were used to assess the association between talking to others following unfair treatment, compared to keeping it to oneself, on self-reported depressive symptoms and perceived stress. The predictor variable was based on the question “If you have been treated unfairly, do you usually talk to people about it or keep it to yourself?” Results: Talking to someone after being treated unfairly was inversely associated with perceived stress (B: -3.62, SE: 1.14, p ≤ 0.05) and depressive symptoms (a: -3.62, SE: 1.14, p ≤ 0.05). Conclusions: African Americans who talked to others in response to unfair treatment had lower depressive symptoms and perceived stress than those who kept it to themselves. More outreach to African Americans regarding the importance of talk in response to exposure to unfair treatment is needed as a potential coping mechanism.
Clinical features and laboratory findings first case of B. 1.617.2 (delta) variant concern (VOC) in Iraq
Authors: Essa Rawand , Ahmed Sirwan , Bapir Dunya , Abubakr Chawan , Rasul Shero , Khdir Awat
Published: August 2021

Introduction and importance:
Since the initial report of severe acute respiratory syndrome (SARS CoV-2) in Wuhan, China in 2019, the virus has constantly mutated, resulting in the appearance of novel variants. In December 2020, the B.1.617.2 (delta) variant concern (VOC) was first reported in India, and rapidly spread around the globe, is now the main brand in the United Kingdom, and it has grown dramatically. The transmission rate of the B.1.617.2 (delta) variant concern is higher origin strain.
Case Presentation:
Here we present the clinical features and laboratory findings of the first case of B. 1.617.2 (delta) variant concern (VOC) in Iraq. A 6-year-old female child presented with severe abdominal pain, headache, severe vomiting and diarrhea, runny nose, alerted mental status, loss of appetite and fever. The patient was diagnosed with COVID-19 delta variant B.1.617.2 by RT-PCR. The patient was treated by administration glucose saline 4% for 3 days, ceftriaxone vial 1 mg every 12 h for 6 days, and an acetaminophen bottle on need to prevent fever followed by a flagyl bottle every 24 h for 3 days.
Conclusion
Vaccination and prevention the spread of the virus and against it are important preventive approaches for delta variant. Sore throat, runny nose, headache, and vomiting, diarrhea are the major clinical features of delta variant. Followed by an elevation of the leukocyte WBC, and blood platelets. To reduce the impact of new delta variant B.1.617.2 infection; hand washing, wearing a double mask, avoiding crowded and closed settings, social distancing, lockdown, and ensuring good ventilation are major significant options against this variant.
Intraoperative Goal-Directed Therapies in Femoral and Pelvic Osteotomies In Children and In-Hospital Postoperative Outcome
Authors: Kumba Claudine
Published: August 2021

Background
Femoral and pelvic osteotomies are potential hemorrhagic interventions where transfusion requirements can be necessary.
Objective
We undertook a secondary analysis of patients who underwent femoral and pelvic osteotomy in the initial cohort. The objective of this secondary analysis was to describe intraoperative, postoperative outcomes and to describe intraoperative management in these patients in terms of blood product management, fluid and hemodynamic therapy with the aims to implement optimization management protocols for postoperative outcome improvement.
Methods
Secondary analysis of patients who underwent femoral and pelvic osteotomy surgery included in the initial retrospective study.
Results
There were eighteen patients with a mean age of 104± 47.1 months. Four (22.2%) patients had intraoperative and or postoperative complications. One patient (5.6%) had intraoperative hemorrhagic shock, two patients (11.1%) had postoperative neurologic failure and one patient (5.6%) had postoperative wound sepsis. Transfusion rate was 50% in nine patients.
Conclusion
Femoral and pelvic osteotomies are interventions where blood, transfusion and fluid requirements can be increased thus this implies the necessity of global patient blood management protocol with point of care tests, with fluid and hemodynamic guided protocols with validated tools in children for intraoperative and postoperative outcome optimization.
Systematic assessment of long-read RNA-seq methods for transcript identification and quantification
Authors: Pardo-Palacios Francisco , Reese Fairlie , Carbonell-Sala Silvia , Diekhans Mark , Liang Cindy , Wang Dingjie , Williams Brian , Adams Matthew , Behera Amit , Lagarde Julien , Li Haoran , Prjibelski Andrey , Balderrama-Gutierrez Gabriela , Çelik Muhammed Hasan , De María Maite , Denslow Nancy , Garcia-Reyero Natàlia , Goetz Stefan , Hunter Margaret , Loveland Jane , Menor Carlos , Moraga David , Mudge Jonathan , Takahashi Hazuki , Tang Alison , Youngworth Ingrid , Carninci Piero , Guigó Roderic , Tilgner Hagen , Wold Barbara , Vollmers Christopher , Sheynkman Gloria , Frankish Adam , Au Kin Fai , Conesa Ana , Mortazavi Ali , Brooks Angela N.
Published: August 2021

With increased usage of long-read sequencing technologies to perform transcriptome analyses, there becomes a greater need to evaluate different methodologies including library preparation, sequencing platform, and computational analysis tools. Here, we report the study design of a community effort called the Long-read RNA-Seq Genome Annotation Assessment Project (LRGASP) Consortium, whose goals are characterizing the strengths and remaining challenges in using long-read approaches to identify and quantify the transcriptomes of both model and non-model organisms. The LRGASP organizers have generated cDNA and direct RNA datasets in human, mouse, and manatee samples using different protocols followed by sequencing on Illumina, Pacific Biosciences, and Oxford Nanopore Technologies platforms. Participants will use the provided data to submit predictions for three challenges: transcript isoform detection with a high-quality genome, transcript isoform quantification, and de novo transcript isoform identification. Evaluators from different institutions will determine which pipelines have the highest accuracy for a variety of metrics using benchmarks that include spike-in synthetic transcripts, simulated data, and a set of undisclosed, manually curated transcripts by GENCODE. We also describe plans for experimental validation of predictions that are platform-specific and computational tool-specific. We believe that a community effort to evaluate long-read RNA-seq methods will help move the field toward a better consensus on the best approaches to use for transcriptome analyses.
Short-time traffic flow prediction based on immune particle swarm neural networks
Authors: Yu Xiaomo , Kang Yuheng , Shen Zhou
Published: August 2021

The concentration-based selection mechanism in the immune theory can avoid the shortcomings of the particle swarm algorithm in balancing population convergence and individual diversity, and enable the improved particle swarm algorithm to optimize the configuration of BP neural network parameters and improve the accuracy of short-term traffic flow prediction. The simulation experiments show that the immune particle swarm optimized BP neural network can effectively improve the prediction accuracy of short-term traffic flow and reduce the prediction error.
Public opinion as an institute of direct democracy
Authors: Rodzinskyi N.I. , Savchenko D.S. , Khaustova M.H.
Published: August 2021

The article is devoted to the problematic form and pressure of the public opinion. Basic attention is the theoretical aspects of understanding of public opinion as the legal and social phenomenon, as exactly due to a presence or absence of foregoing institute of civil society it is possible to talk about the state and level of democratization of society, taking into account active introduction of processes that provide access and participation of citizens in life of the state. A self concept «public opinion» though has the generalized interpretation and interpretation in a modern kind, however during all way of forming tested quite a bit transformations and modifications. The presence of different conceptions to understanding of the phenomenon of public opinion is first of all explained variety of looks to influence of actors on the origin of public opinion. Scientists in the doctrine of sociology and legal sciences examine public opinion as phenomenon of mass consciousness that has elemental character, a social institute, a social regulator, that brings in the effective contribution to the decisions of question, that touch activity of the state. For today three basic going was formed near understanding of public opinion as social and legal phenomenon – morally-normative that was based on public publicity and openness, approach, that was based not on subject composition, but on thematic, denying here influence of mass character on the process of forming of public opinion and approach demoscopy is fixed in basis of that – research the key aspect of that is realization of analysis of public opinion on the basis of quantitative data. The classic going near understanding of public opinion from the point of view of her nature is conception of V. Lipman, in basis of that influence of environment of existence of individual is fixed on the process of forming of public opinion. In this theory attention is accented on that a human is clearly limited to in informative space the capacity for perception of information, and that is why can not grasp her fully, however this factor plays role of positive factor of forming of public opinion, as it gives an opportunity more deep knowledge in certain industry, creating more organized public opinion that does not limit opinion of every individual here. As well as on any institute of direct democracy on public opinion certain functions – expressive, consultative, directive functions. Due to realization of foregoing functions public opinion there is cooperating of public with organs by the state of power, that it is counted on formation of original symbiosis, the aim of that is creation of positive terms for life of citizens, increase of level of democratization in society, to improve quality and efficiency of realization of the functions fixed on them power within the framework of legislation.
Problems of decentralization reform implementation in Ukraine and ways to solve them
Authors: Logvynenko M.I. , Tsymbal A.E.
Published: August 2021

The present article deals with the decentralization reform in Ukraine, definition of basic concepts, in particular, «decentralization», «local self-government», «territorial community» has been installed, on the European Charter of Local Self-Government, as a fundamental international normative document, proclaiming the foundations of decentralization has been focused attention, the main conceptual document in the field of decentralization reform at the national level has been defined, problematic issues of decentralization reform implementation in Ukraine has been isolated, in the absence of a proper mechanism of legal regulation has been focused attention, after all, the new administrative-territorial system is not prescribed in the Constitution of Ukraine, on the inconsistency of the publicly announced goals of decentralization reform with the real actions of the authorities within the reform, contradictions regarding the legal status of the prefect in the system of renewed local self-government mechanism, irrationality of association of some territorial communities, legal unregulation of land decentralization procedure has been focused attention, negative impact of the consolidation of settlements, optimization of the network of medical institutions on life in territorial communities has been installed, issues of land decentralization and its consequences for citizens has been analyzed, bring in line the mechanism of legal regulation of issues related to decentralization reform, including, make appropriate changes to the Basic Law, adopt the Law «On the Principles of Administrative and Territorial Organization of Ukraine» and other legal acts necessary for the implementation of the reform has been suggested, on the need to bring national legislation into line with the European system of legal regulation has been emphasized, on the need to learn the experience of foreign countries in the field of decentralization reform has been focused attention, the expediency of revising the mechanism of community formation, which should be objective and consistent with the principle of economic efficiency has been installed, prospects for further research on the topic of decentralization reform in Ukraine has been defined.
The essence of the concept of "tax security"
Authors: Kulish A.M. , Kondieiev Y.S.
Published: August 2021

An article deals with analysis of the concept “tax”, determination of its role in a market reform, as well as a list of financing from tax receipts. The levels of tax security are determined: national (state), regional, of tax payers. In tax security such an element as the tax security of enterprises is defined. A substantial characteristics of a term “tax security” is given, for which an economic, social, legal elements and principles of functioning of the above mentioned concept were determined. The characteristics of a category “tax culture” is given. Authors of the article indicated that trust and cooperation between all participants of tax relations facilitate the development of a tax culture, which will result in building of effective national economy and reliable tax security of a country. The essence, concepts, purpose, tasks, methods and principles of construction of the economic nature of tax security are analyzed. The main risks, threats, expectations and results of its effective construction are identified. In this article main indicators of tax security are determined and their types are listed. Several concepts of “tax security” are given. Emphasis is focused on the lack of a single concept for defining tax security at the legislative level, which would indicate the priorities, goals and objectives, ways to ensure tax security of the state. The conclusion summarizes the main provisions that are necessary for the legal (legislative) consolidation of the concept of "tax security": criteria for distinguishing tax security from other types of security; set specific tasks and address the issue of ensuring effective interaction of entities in the tax sphere; will consolidate an additional indicator, such as the importance of paying their own contribution by taxpayers, which leads to the stability of the tax system.
Problematic issues of identification of a person as the main tool of combating money laundering in the circulation of electronic money
Authors: Starynskyi M.V. , Khutorіanets Zh.V.
Published: August 2021

The article investigates some problematic issues concerning identification of persons that perform financial operations as the main way to combat money laundering in the cycle of e-cash. It draws readers’ attention to the speedy development of the Internet technologies that results in the increasing popularity of new payment systems including e-cash. It is emphasized that the advantages provided to some people by the use of e-cash in their economic operations can be used by other persons for certain criminal purposes. In this aspect e-cash has found its extensive application in the grey sector of the world economy and as such requires a more intensive control over its use. The authors of the investigation prove that identification of the persons using payment tools is currently one of the most effective ways to prevent e-cash from being used in illegal activities. International organizations whose purpose is to combat money laundering always recommend different states to improve their mechanisms of the identification of the persons involved in financial operations. The analysis of person’s identification applied to the customers of financial operations proves that the basic mechanism of reliable identification is the list of documents that identify a person being fixed in the national laws. The range of these documents and their quality vary in different countries, thus proving the peculiar features of these states. The issue of the identification of financial operation customers is in Ukraine in the phase of its intense formation. The laws establish only the main documents to identify a person. At the same time, in our opinion, the legislation currently in effect must foresee complete lists of the documents that a bank institution has the right and possibility to ask for with view of person’s identification. Such lists must take into consideration not only average situations but also cases of natural disasters, socio-political changes in the society, presence of the person on the territory of another country, etc. The approval of such lists should allow banking institutions to duly observe the provisions of our national legislation designed to prevent money laundering.
Problems of inheritance in the anti-terrorist operation zone and in the occupied territories
Authors: Goncharova A.V. , Chuikova V.Yu.
Published: August 2021

In this article, the authors reveal the issue of inheritance in the anti-terrorist operation zone and in the occupied territories. The institution of inheritance in the civil law system is one of the most important issues of research, its importance is due to the fact that the object of inheritance is the right of ownership. The issue of inheritance in the controlled territories remains relevant. This applies to both subjects and objects of inheritance rights. The article emphasizes that in accordance with the Declaration of State Sovereignty of Ukraine and the Constitution of Ukraine, the sovereignty of Ukraine extends to its entire territory, which within the internationally recognized state border is integral and inviolable. Indicated. That within the temporarily occupied territories there is a special procedure for ensuring the rights and freedoms of the civilian population, defined by the legislation of Ukraine. Individuals, regardless of their registration as internally displaced persons or their acquisition of special legal status, and legal entities retain the right of ownership, other real rights to property, including immovable property, including land plots temporarily occupied territories, if such property is acquired in accordance with the legislation of Ukraine. It is noted that the activities of armed groups and the occupation administration are illegal, and any act issued in connection with such activities is invalid and does not create any legal consequences. Emphasis is placed on the fact that the process of inheritance on Ukrainian lands is unchanged, namely, by will and by law. Inheritance by will occurs if the deceased person made a will before death and it is valid. In his absence there is an inheritance by law. Inheritance by law takes place in the following cases: absence of a will; invalidation of the will; the death of the heirs specified in the will before the opening of the inheritance or their refusal to accept the inheritance; the testator revoked a previously made will and left no new one; the will was declared invalid by a court; if the will does not cover all the property belonging to the testator.
The health care system: an overview
Authors: Kyselova O.I. , Nadtochiy K.O.
Published: August 2021

Health care is the most important social sphere of society, on the state of which depends not only the health of the population, but also the political stability of the state. The health of the population is the basis of its well-being, the development of society in its social and economic expression. Recently, the health problems of the population have been repeatedly considered in connection with strengthening the security of the country, the development of urgent measures to maintain the health of less vulnerable groups in difficult conditions of socio-economic transformation. Healthcare is an integral part of international development. An effective health care system can make a significant contribution to the country's economy, its development and industrialization. Health care is an important factor that determines the general physical and mental health, well-being of people not only in one country but also around the world. Health care as the leading branch of activity of the country, the purpose is the organization and maintenance of accessible medical care of the population. It is the main element of national security. Is a set of measures of economic, political, social, legal, scientific, medical, sanitary, anti-epidemic and cultural nature, aimed at preserving and strengthening the physical and mental health of each person, maintaining a healthy life and, in this case, deteriorating health I, then - the provision of medical care. Special social institutions are created for this purpose. This article analyzes the relevance of health care and examines that these issues are major and health care is a leading sector of Ukraine, which aims to organize and provide affordable health care.
Strategic directions and prospects for improving the activities of the Supreme Court on intellectual property
Authors: Kuryava V.V.
Published: August 2021

The evolution of intellectual property has led to a steady increase in their importance to the modern world economy. Intellectual property has become the highest indicator of the competitiveness of the modern state. Today, the objects of intellectual property rights are the driving force of state policy in all its spheres - economy, health care, security, food, labor, trade, environment, etc. In recent decades, in modern political conditions, the relationship between the executive and the legislature has changed, which has had an impact on the place and role of the judiciary in this system. This article is aimed at studying the modern institutional foundations of the formation of the judicial system in modern political conditions. The interaction of public authorities in the context of decision-making on the establishment and organization of security, in particular the High Court of Intellectual Property, is studied. Our country is endowed with high scientific potential, as evidenced by the state of scientific, technological and innovative development. However, difficulties in the field of commercialization, protection and defense of intellectual property rights cause large-scale losses to our state, reduce the competitiveness of intellectual property rights. Among such problematic aspects is the lack of an effective system of judicial protection of intellectual property rights: instability of conditions for inventive and innovative activities; underdevelopment of elements that ensure the commercialization and protection of patented achievements; use of unlicensed software, counterfeit and counterfeit goods; high level of Internet piracy; inefficient and non-transparent royalty collection system; lack of an effective judicial protection system. This situation creates real economic problems and threats to our state, which require their immediate solution, scientific justification of the mechanism for overcoming them. Modern conditions for the development of public administration in Ukraine significantly affect the interaction of all branches of government, balancing their interaction and interaction, including the judiciary. The political influence on the judiciary is especially acute, which increases the attention to the problems of institutional support of the newly created court.
Theoretical and legal bases of protection of business entities from raiders in Ukraine
Authors: Horobets N.S. , Pylypenko Ye.S.
Published: August 2021

The article is devoted to the study of theoretical and legal principles of protection of business entities from raids in Ukraine due to the low level of quality of the system of protection of private property rights in the state. It is stated that for small enterprises the lack of financial resources and the risk of illegal seizure or takeover, ie "raiding", is a more common problem, but large enterprises are also subject to raids. It was found that raiding is a real threat to the integrity of enterprises, stable economic development and information security of the state, its danger is confirmed by data on the number of raider seizures of property in Ukraine. It is noted that one of the areas of counteraction to raiding is the consolidation at the legislative level of a common understanding of this concept, but the Civil Code of Ukraine, the Law of Ukraine "On Joint Stock Companies" deals only with certain aspects of raiding. Features of "white", "gray", "black" raiding are revealed. There are two ways to warn and protect businesses from raiding: the use of government tools and self-preventive protection of the enterprise. The state instruments of warning and protection of enterprises from raids include: legislative guarantees of inviolability of property and protection of property rights of enterprises in case of violation, criminal liability for misappropriation of property, the procedure of state registration of property rights, the right to apply for protection of rights and interests to the court and the Office for Combating Raiding at the Ministry of Justice of Ukraine. It is emphasized that only 20% of enterprises independently protect themselves from raider encroachment, which explains the large number of raider seizures in Ukraine. Among the methods of such protection, emphasis is placed on creating a reliable system of protection of information about the company, ensuring timely and full payment of dividends to shareholders, preventing the mass purchase of shares and monitoring the current situation. It is concluded that it is expedient to develop and consolidate at the legislative level a common understanding of the concept of "raiding", guarantees of warning and protection of business entities from raiding in Ukraine, improving the powers of courts and the Office for Combating Raiding in Ukraine to consider issues of registration of property rights of enterprises.
State border as an object of administrative and legal activity of the State Customs Service
Authors: Ilchenko O.V.
Published: August 2021

Protection of the state border is one of the most important functions of the state. The state border is a feature that should be inherent in any state and without which its existence is impossible. Areas of territorial sovereignty of states are determined by the boundaries established between them. Thus, the main purpose of borders is to establish the boundaries of state territories. No state can exist without a legally defined territory. However, the geopolitical state attribute is the relevant political space, which is determined by state borders, which are enshrined in national and international law. The proper functioning of any country, the level of its social and economic development directly depends on the reliable protection, defense and stability of state borders. An integral part of the state border policy and state and legal regulation is the creation of an effective, perfect legal framework and conditions for ensuring the sovereignty, territorial integrity and inviolability of Ukraine, taking into account the current security challenges related to state regulation of border security. , protection and defense of the state border in general and administrative and legal regulation in particular. Ukraine's European integration policy, globalization processes taking place in the world, manifestations of foreign aggression affect border policy and require finding ways to increase the level of reliability of protection and protection of the state border as the main attribute of its sovereignty, territorial integrity and important national security of Ukraine. An important measure to increase Ukraine's border security is the implementation in Ukraine of the project "EU Support to Strengthening Integrated Border Management in Ukraine (EU4IBM)" funded by the European Union and implemented by the International Center for Migration Policy Development (ICMPD). The implementation of the Project will provide an opportunity to identify and eliminate shortcomings in the implementation of reforms that will help bring the national border management system closer to the standards and best practices of the European Union.