bluuebunny/crossref_metadata_2025 huggingface dataset:
A Cohort Study: Caspase-3 As Prognostic Factor of Radiation Therapy in The Advanced Stage of Cervical Cancer (IIB-IIIB) Patients
Authors: Udiyanto Hermawan , Mudigdo Ambar , Sulistyowati Sri , Purwanto Bambang , Widyaningsih Vitri , Wasita Brian
Published: November 2020

Background: The treatment of the advanced stage of cervical cancer (stage IIB, IIIB) using internal (brachitherapy) and external radiation therapy raises question in how to determine the prognosis of the disease. The role of caspase 3 in predicting radiation response in the advanced stage of the cervical cancer (stage IIB-IIIB) is still unknown. This study aim to analyze the role of Caspase-3 expression as a prognostic factor of radiotherapy in patients with the advanced stage cervical cancer.Methods: This study is an analytical cohort prospective study from June 2019 to February 2020 in the Department of Obstetrics and Gynecology in association with the Department of Anatomic Pathology of Dr. Moewardi General Hospital, Surakarta, Indonesia involving 40 patients diagnosed with cervical cancer. The staging of cervical cancer was determined using the FIGO 2019 staging system. The Caspase-3 expression level were determined using immunohistochemical examination. The association between the caspase 3 expression and changes of tumor volume is analyzed using chi square and fisher exact test for parametric and non-parametric test, respectively. A p-value of less than 0.05 is considered to be statistically significant.Results: The analysis shows that there is a significant association between the Caspase -3 expression and the changes of tumor volume (p = 0.04). The odds of the changes of tumor volume in the score 3 of the caspase -3 expression is 22.67 times higher than the score 2 of the caspase-3 expression (95%CI, 1.56 - 328.95, p=0.04).Conclusion: Caspase-3 expression has a significant association with the changes in the tumor volume of the advanced stage cervical cancer.
The lateral supramalleolar flap as solution for lower leg, ankle and foot defects: a surgical case series
Authors: Nsaful Kwesi Okumanin , Gentil Stephane
Published: November 2020

Introduction. One of the most challenging regions of the body to cover is the lower part of the leg, the ankle, and the foot, especially with the exposure of bones or tendons. Many options for covering soft tissue defects in this area have been proposed. This article describes the lateral supramalleolar flap, which is used for the reconstruction of defects of the lower leg, ankle, heel, and foot. This flap is a surgical technique to salvage the lower extremity due to its large skin paddle and a wide rotation arc. In this case series, patients with lower leg and ankle defects requiring flaps had the lateral supramalleolar flaps performed. This article discusses the overview, technique, and outcomes.Methods. These flaps were performed under spinal anesthesia and tourniquet control.Â  The upper limit of the flap was about 8 cm from the popliteal crease, and the lower border was 5 cm from the axis of the ankle joint. The lateral extent of the flap was up to the fibula, contrary to mid-calf. The flap was harvested in the sub-facial plane, and the donor site was grafted.Results. The Flap was generally easy to raise and secure in place at the donor site. Partial necrosis of the flap was reported in one case. The overall donor site morbidity was minimal.Conclusion. The lateral supramalleolar flap is a reliable and useful flap for coverage of the lower third of the leg, ankle, and dorsal foot defects. It is a viable option available to the reconstructive surgeon, especially with the exposure of bones or tendons.Â
Collaborative management of pediatric duplex collecting system with upper pole hydronephrosis, vesicoureteral reflux, and ureterocele: A case report
Authors: Budhiarta Kirana Dyah Larasati , Suarta Ketut , Duarsa Gede Wirya Kusuma , Anandasari Pande Putu Yuli
Published: November 2020

Congenital anomalies of the kidney and urinary tract (CAKUT) is an uncommon finding with challenging diagnosis establishment and potentially devastating long-term renal outcome. We describe a case of unilateral duplex collecting system with upper pole vesicoureteral reflux and lower pole ureterocele. This 4-year-old female with prior antenatal assessment of kidney abnormality presented with recurrent urinary tract infection. A multidisciplinary approach was employed to encourage comprehensive diagnostic workup and management strategy. The complexity of such a rare case warrants higher index of suspicion and coordinated collaboration of a multispecialistic team.
Comparison of direct medical cost between ramipril and candesartan in hospitalized acute decompensated heart failure at West Nusa Tenggara Regional Hospital
Authors: Qiyaam Nurul , Nopitasari Baiq Leny , Nopitasari Baiq Leny , Rahmawati Cyntiya , Nurbaety Baiq , Pratiwi Emasiska Ajeng
Published: November 2020

Introduction: Pharmacoeconomy is the field of study regarding costs analysis associated with the use of drugs in health care. The purpose of pharmacoeconomics is to compare a different drug used in the treatment with the same condition or can be the opposite, i.e. comparing different treatments in different circumstances. The purpose of this study is to determine and compare the average efficiency of direct medical costs between ramipril and candesartan combination drug in hospitalized heart failure patients with a payer perspective at the West Nusa Tenggara Regional General Hospital, Mataram, Indonesia.Method: This study is part of an economic evaluation of direct medical cost analysis research in hospitalized heart failure patients with a payer perspective. Study design using a retrospective approach involving 45 patients with heart failure who met the study inclusion criteria and exclusion criteria. Independent t-test was used to compare the direct medical cost between ramipril and candesartan.Results: The average gross total cost of using ramipril combination was Rp. 4,197,011 while the average total cost of using candesartan combination was Rp. 3,099,088. These results indicate there are savings in the average total cost of treatment for heart failure using candesartan that is Rp. 1,097,923. Candesartan combination provides the lowest value and is a more efficient choice compared to ramipril combination. Meanwhile, after t-test comparison reveal no significant different average direct medical costs in patients using the ramipril combination compared with the candesartan combination (p>0.05).Conclusion: The results of this study indicate that there is no significant difference between the average direct medical costs in patients using ramipril compared with candesartan combination.
Bacterial identification of acne vulgaris
Authors: Sari Lovena , Jusuf Nelva Karmila , Putra Imam Budi
Published: November 2020

Background:Â Acne vulgaris (AV) is a chronic inflammation of the pilosebaceous unit with clinical polymorphic lesion consist of non-inflammatory (open and closed comedones) and inflammatory lesions (papules, pustules, and nodules) with varying degree of inflammation and depth. Earlier studies showed that other bacteria might also found and played a role in acne pathogenesis besides Cutibacterium acnes (C. acnes).Patients and Methods:Â  This descriptive observational study used cross-sectional method. Samples were collected from 40 subjects with AV. We took the samples from non-inflammatory (closed comedones) and inflammatory lesions (pustule) in each subject, followed by Gram staining, aerobic and anaerobic bacterial culture, and bacterial identification. This research has been approved by the Ethical Committee, Faculty of Medicine, University of Sumatera Utara.Results:Â There were 12 bacterial species that were identified from 80 samples. We identified Cutibacterium acnes (21,2%) in anaerobic culture. While in aerobic culture, we identified Staphylococcus epidermidis (47,5%), Staphylococcus hominis (17,5%), Staphylococcus aureus (8,7%), Staphylococcus haemolyticus (8,7%), Leuconostoc mesentroides (6,2%), Micrococcus luteus (3,7%), Kocuria varians (2,5%), Staphylococcus vitulinus (1,2%), Staphylococcus cohnii (1,2%), Staphylococcus arlettae (1,2%) and Dermacoccus nishinomyaensis (1,2%).Conclusion:Â The two most common bacteria in acne vulgaris are Staphylococcus epidermidis and Cutibacterium acnes
Correlation between postherpetic neuralgia (PHN) patientsâ€™ stress level and the quality of life of their families in Universitas Sumatera Utara Hospital
Authors: Angkasa Finisia , Putra Imam Budi , Yosi Ariyati
Published: November 2020

Background: Postherpetic neuralgia (PHN) is the most common complication seen in herpes zoster patients. Its clinical manifestations consist of persisting sharp pain even when the initial exanthema has disappeared. These patients experienced stress from the conditions and from the treatment process, which in turn affect their familiesâ€™ quality of life.Patients and Methods: This study was an observational analytic study with a cross-sectional design involving 30 PHN patients and their families. Patients were required to fill out the Perceived Stress Scale (PSS-10) questionnaire to assess their stress levels. Their respective families were required to fill out the Family Dermatology Life Quality Index (FDLQI) questionnaire to assess their quality of life. Statistical analysis was performed on both data with the Spearman correlation test (data were not normally distributed). ANOVA test was performed to assess the average difference between the stress levels experienced by PHN patients and the quality of life of their families.Results: The families of PHN patients who experienced severe stress levels had worse or lower quality of life compared to the families of patients with moderate or mild stress levels. The lowest average score of quality of life is 27.20 (severe stress level) and the highest average score of quality of life is 14.33 (mild stress level).Conclusions: The stress level of PHN patients was significantly related to the quality of life of their respective families in the aspects covered in the FDLQI questionnaire (p <0.005). There was a significant difference in the family's quality of life score based on the patient's stress level (p<0.001)
Virtual patient simulation method for learning and assessment in cardiology field
Authors: Putra Manuaba Ida Bagus Amertha , Santika Dewi Ni Gusti Ayu Putu Lestari , Prabawa I Putu Yuda , Bhargah Agha , Darmayani Sri , Wu Chien-Chih
Published: November 2020

Virtual patient simulation (VPS) is an online computer simulation system that contains patients' clinical situation to train and realistically assess clinical abilities with supplemental animation, demonstration of anatomy, ECG tracing, etc. It can be used for teaching, learning, and assessment supports learning. Until now, it is difficult to ascertain how many VPS systems have been used today in the world, both for learning and assessment, especially in cardiology medicine field. We searched for all research using the term "virtual patient in medical education, virtual patient in cardiology & virtual patient simulation in cardiology" in the title or research abstract from 2014 until 2019. In this current review, we will describe the use of VPS for learning and assessment purposes in cardiology medicine field.Â
Analisis korelasi kadar serum prokalsitonin dengan jumlah leukosit pada penderita dengan kecurigaan sepsis di RSUP Sanglah, Bali, Indonesia
Authors: Dharma Bagus Dwiki Arya , Mulyantari Ni Kadek , Prabawa I Putu Yuda
Published: November 2020

Background:Â Sepsis is a systemic inflammatory response to infection, where the pathogen or toxin is released into the blood circulation, causing activation of the inflammatory process. Laboratory tests are used to detect inflammatory processes, one of which is procalcitonin. This study aims to determine the correlation between procalcitonin (PCT) serum levels by the leukocytes counts on suspected sepsis patients at Sanglah Hospital in Denpasar.Methods:Â An analytic observational study with the cross-sectional design was conducted among 21 samples by consecutive sampling technique. The population in this study were sepsis patients who were treated at Sanglah Hospital Denpasar during February-June 2016 period. Data were analyzed using SPSS version 17 for Windows.Â Results:Â Â Most of respondents were >35 years old (85.7%), Body Mass Index (BMI) > 20 kg/m2 (76.2%), leucocyte counts < 10.000/Î¼L (42.9%), and PCT levels â‰¤ 0.5 ng/mL (61.9%). There is no significant correlation between white blood cells (WBC) and PCT by Spearman Correlation test (p=0.061; r=0,641).Conclusion:Â The recent findings suggest that there was no significant correlation between PCT serum levels with the leucocytes counts among patients with sepsis.Â Latar Belakang: Sepsis merupakan suatu respon inflamasi sistemik terhadap infeksi, dimana patogen atau toksin dilepaskan ke dalam sirkulasi darah sehingga terjadi aktivasi proses inflamasi. Tes laboratorium yang digunakan untuk mengetahui adanya proses inflamasi salah satunya adalah prokalsitonin (PCT). Penelitian ini bertujuan untuk mengetahui korelasi antara kadar serum prokalsitonin dengan jumlah leukosit pada penderita dengan kecurigaan sepsis di RSUP Sanglah Denpasar.Metode: Penelitian observasional analitik dengan desain tong lintang dilakukan terhadap 21 sampel dengan teknik konsekutif. Populasi dalam penelitian ini adalah pasien sepsis yang dirawat di Rumah Sakit Sanglah Denpasar selama periode Februari-Juni 2016. Data dianalisis menggunakan SPSS versi 17 untuk Windows.Hasil: Sebagian besar responden berusia> 35 tahun (85,7%), Indeks Massa Tubuh (IMT)>20 kg / m2 (76,2%), jumlah leukosit <10.000 / Î¼L (42,9%), dan tingkat PCT â‰¤ 0,5 ng / mL (61,9%). Tidak terdapat korelasi yang bermakna antara sel darah putih (WBC) dan PCT dengan uji Korelasi Spearman (p = 0,061; r = 0,641).Kesimpulan: Hasil penelitian saat ini menunjukkan bahwa tidak terdapat korelasi yang bermakna antara kadar serum PCT dengan jumlah leukosit pada pasien dengan sepsis.
Mean platelet volume count as a risk factor for bloodstream infection in Pediatric Ward Sanglah General Hospital Denpasar, Bali-Indonesia
Authors: Wirantari Ni Putu , Gustawan I Wayan , Utama Made Gede Dwilingga , Arhana Bagus Ngurah Putu , Fatmawati Ni Nengah Dwi , Tarini Ni Made Adi
Published: November 2020

Background: Mean platelet volume (MPV) is a potentially interesting parameter in predicting bacteremia in patients admitted with suspected community-acquiredÂ  infections. The incidence of bacteremia, defined as the presence of viable bacteria in the bloodstream, in patients who were being admitted to hospital. Multiple recent studies have confirmed that low-level bacteremia is more common than previously thought, occurring in 38% to 68% of all pediatric patients with a positive blood culture. The mortality rate is 25%â€“30%, increases to 50% when associated with severe sepsis. The objective of this study is to investigate whether MPV as a risk factor for bloodstream infection.Methods: This was a hospital-based case-control study, review of the medical record from January 2016 until December 2018. We collect age, gender, MPV, platelet and blood culture. We analyze the association between MPV to bloodstream infection.Result: Between January 1st 2016 and December 31st 2018, there were 86 patients with positive blood cultures and 89 negative blood cultures. In the case group, there were 48 (53.9%) male and 41 (46.1%) female subjects, while in the control group there were 63 (73.3%) male and 23 (26.1%) female subjects. The median age for case group was 14 months while the median age for control group was 23 months. From the ROC curve, the optimal cutoff value for MPV was determined as 5.59. The odd ratio determined the relationship between MPV to blood stream infection was 2,26 with 95% CI 1.13-4.52. The adjusted odds ratio was 2.24 95% CI (1.10-4.57). The majority diagnosis was pneumonia (46.1%) in case group then early onset neonatal sepsis (28.1%) and meningitis (7.9%).Conclusion: The MPV â‰¥5.59 is a risk factor for developed bloodstream infection. This result can be used as a cutoff point to initially administered antibiotic to prevent the worse prognosis (sepsis, multiple organ failure, and death).
Self-foreign omphalitis in adult: a case report
Authors: Soesilo Daniel Ardian , Baby April
Published: November 2020

Introduction: Severe omphalitis in adults is rare and can be caused by both congenital and acquired etiologies. We are reporting an impacted self-foreign-body in omphalitis case induced by accumulated keratin fragments.Case: A 28-year-old overweight male presented with a 3-day history of persistent purulent umbilical discharge with a remittent fever a few days before, constant abdominal tenderness with edema and erythema around navel area. There were no other GIT-related symptoms. He was given oral antibiotics, which showed no improvement. Upon surgery, we examined deep umbilical cavity without urachal connection to the navel. From the umbilical cavity scooped out multiple polypoid umbolith debris. Histopathologic examination revealed pyogenic granuloma with numerous keratin fragments without any foreign bodies.Conclusion: An impacted and infected self-foreign-body may be a cause of omphalitis in adults and could lead to severe and wide-spread infection if left untreated.
Hubungan proteinuria dan batu saluran kemih: studi analitik
Authors: Ali Zulfikar , Arianto Eko
Published: November 2020

Latar Belakang: Batu saluran kemih (BSK) masih merupakan salah satu masalah tersering yang dihadapi urolog. Proteinuria dapat ditemukan pada kondisi gagal ginjal kronis (GGK), infeksi saluran kemih (ISK), keganasan, ataupun BSK. Protein urin diketahui berperan dalam proses supersaturasi dan agregasi BSK. Studi terkini menemukan hubungan protein marker urin dengan BSK pada level molekular setelah proses elektroforesis. Penelitian ini bertujuan untuk mengetahui hubungan proteinuria pada urinalisa dengan BSK.Metode: Penelitian ini adalah penelitian studi potong lintang dengan subjek pasien poli urologi di RSUD Kardinah, Tegal. Total sampel 200 pasien yang dikelompokkan menjadi 100 pasien BSK dan 100 pasien kontrol. Seluruh pasien dilakukan pemeriksaan ultrasound (USG) sebagai pemeriksaan diagnosis awal, kemudian dilakukan pemeriksaan urinalisa. Proteinuria dianggap positif untuk nilai protein urin +1 sampai +4 dan negatif pada nilai protein urin trace dan negatif. Variabel lain yang dianalisa adalah ISK, ph urin, usia, dan jenis kelamin.Hasil: Pasien laki-laki memiliki kecenderungan BSK yang lebih tinggi dibandingkan perempuan dengan rasio 1,8:1. Rentang usia kelompok BSK 23-78 tahun dan pada kelompok kontrol 17-85 tahun. Tidak didapatkan hubungan yang bermakna antara proteinuria dengan BSK (p = 0,203). Terdapat hubungan antara ISK dengan BSK (p = 0,002) dan ph urin dengan BSK (p = 0,024). Terdapat hubungan antara ISK dengan proteinuria pada uji univariat dan multivariat (p = 0,000).Kesimpulan: Tidak didapatkan hubungan antara proteinuria dengan BSK. Terdapat hubungan antara proteinuria dengan ISK. Proteinuria muncul karena proses inflamasi pada kasus infeksi akibat batu. Penelitian lanjutan diperlukan untuk menentukan jenis protein urin yang menjadi inhibitor pada pasien non stone former dan jenis protein urin yang ditemukan pada stone former.
The association between Body Surface Area (BSA) and vitamin D level among obese adolescent patients in Denpasar, Bali, Indonesia
Authors: Yuliadewi NS Luh Gede , Sidiartha I Gusti Lanang
Published: November 2020

Background:Â Prevalence of obesity in adolescent in Indonesia is still high. An obese adolescent is likely to stay obese into adulthood and tends to develop into cardiovascular and metabolic diseases. Obese subjects have larger body surface area and should be able to produce more vitamin D from cutaneous synthesis. This study aims to determine the prevalence of obesity in adolescent in Denpasar, determine vitamin D status among obese adolescents and obtained an association between body surface area and vitamin D levels.Methods:Â A descriptive observational study using a cross-sectional approach has been conducted among 51 obese adolescents in Denpasar during May to December 2018. Several variables assessed in this study were age, sex, weight, height, Body Mass Index (BMI), Body Surface Area (BSA), and vitamin D levels. Factors associated with vitamin D levels in obese adolescence were analyzed with appropriate statistical analysis. Data were analyzed using SPSS version 17 for Windows.Â Results:Â From 51 subjects, 32 (62.74%) male and 19 (37.26%) female subjects were enrolled in this study. The mean weight and height of respondents were 89.4Â±9.8 kg and 158.6Â±7.3 cm. In addition, the average Body Mass Index (BMI) and Body Surface Area (BSA) were 33.6Â±3.4 kg/m2 and 2.1Â±0.2 m2. The mean Vitamin D levels was 18.9Â±4.9 ng/mL with 40 subjects (78,4%) were known in a vitamin D deficiency state. There was a significant weak positive association between BSA and vitamin D levels (r=0.32; p=0,002).Conclusion:Â Most obese adolescents were in vitamin D deficiency with a significant weak positive association between BSA and vitamin D levels.Â
Revascularization limb salvage in chronic limb-threatening ischemia: does open surgery still the best option in the era of endovascular therapy?
Authors: Anhar Ashabul , Habibie Yopie Afriandi
Published: November 2020

Introduction: Chronic limb-threatening ischemia (CLTI) is considered the most severe pattern of peripheral artery disease. It is defined by the presence of chronic ischemic rest pain, ulceration or gangrene attributable to the occlusion of peripheral arterial vessels who suffered from diabetes mellitus type 2, and also associated with physical, as well as psychosocial, consequences such as amputation and depression. Successful revascularization decreases the major amputation rate in patients with CLTI. The efficacy of peripheral bypass grafts and percutaneous transluminal angioplasty in accomplishing limb salvage has been recognized.Case Description: A 42-year-old man came to the RSUZA emergency room with chief complaints claudication above the right thigh and continuous pain (rest pain) at the right lower extremity since 9 months ago. History of finger amputation 2nd, 3rd and 4th right foot since 10 months ago at local hospital, and now there are necrotic wounds on his toes. Patients suffered from type 2 diabetes mellitus and have bad habits such as smoking 3 packs a day all the time. Physical examination has a wound in the lower leg area of more than 10 cm x 8 cm. Right ankle-brachial index (ABI) 0.6 and left ABI 1.3. CT-angiography (CTA) shows infra inguinal type D TASC II classification. A revascularization procedure is performed to salvage the limb with the right femoro-popliteal bypass technique with graft R-SVG and debridement in the right lower leg area so that chronic right lower limb ischemia can be overcome. Systemic heparinization was given post operatively and complaints of pain in the right lower limb begin to disappear. Patient was discharged on the 5th day of treatment with good results.Conclusion: Open surgical bypass continues to be a primary treatment of choice, durable approach in a significant proportion of patients. Lower extremity bypass grafting is most successful with a good quality, long, single-segment autogenous vein of at least 3.5mm diameter.Â
Pola pasien anemia yang berkunjung ke Poliklinik Hematologi RSUP Sanglah dari April 2015-April 2017
Authors: Ayu Sintya D Ni Made , Losen Adnyana I Wayan , Suka Aryana IGP
Published: November 2020

Introduction: Anemia is a clinical condition associated with many causes. Anemia is not a disease, it is a syndrome and generally described as a decreased of red blood cell mass and hemoglobin below the normal level. Based on WHO's criteria, someone can be diagnosed with anemia if their hemoglobin level falls below 130 g/L for men and below 120 g/L for women. Based on a survey made by WHO, about one from every four people in the world suffered from anemia.Aim: The study aims to evaluate the patient arrival pattern to the Hematological Policlinic in RSUP Sanglah Denpasar.Â Method: This is analytic observational research of the anemic patient who came to the Hematological Policlinic in Sanglah General Hospital from April 2015-April 2017.Result: The highest proportion of anemic patient who came to Hematologic Policlinic in Sanglah General Hospital based on age classification are the age group of 15-59 while based on sexes the percentage of the anemic male patient is 44.2%, and the anemic female is 55.8% while 2.9% of that female is currently pregnant.Conclusion: From the causative point of view, the anemic patient in Hematologic Policlinic in Sanglah General Hospital from April 2015 to April 2017 mostly diagnosed with unspecified type while 58.7% of the anemic patient come without another health issues and the other 41.3% have had underlying or accompanying diseases.Introduction: Anemia merupakan suatu kondisi klinis yang diasosiasikan dengan banyak penyebab. Anemia bukan merupakan suatu penyakit melainkan suatu syndrome dan pada umumnya didefinisikan sebagai penurunan sel darah merah dan hemoglobin di bawah nilai normal. Berdasarkan kriteria WHO, seseorang dapat didiagnosis Anemia jika hemoglobinnya berada di bawah 130 g/L untuk laki-laki dan di bawah 120 g/L untuk perempuan. Berdasarkan survey yang dibuat oleh WHO, anemia diderita oleh satu dari empat orang di dunia.Tujuan: Penelitian ini bertujuan untuk mengetahui pola kunjungan pasien ke Poliklinik Hematologi RSUP Sangah Denpasar.Metode: Penelitian ini merupakan suatu penelitian observasional pada pasien anemia yang datang ke poliklinik hematologi RSUP Sanglah dari April 2015-April 2017.Hasil: Berdasarkan penelitian ini dapat dikonklusikan bahwa proporsi tertinggi pasien anemia yang datang ke Poliklinik Hematologi RSUP Sanglah paling banyak adalah dari kelompok umur 15-19 tahun. Sementara itu, berdasarkan kelompok jenis kelamin ditemukan bahwa presentasi pasien anemia perempuan adalah 55,8% dengan 2,9% dari pasien tersebut sedang dalam keadaan hamil sementara pasien anemia laki-laki adalah 44,2%.Simpulan: Dilihat dari penyebabnya pasien anemia yang datang ke Poliklinik Hematologi RSUP Sanglah dari April 2015-April 2017 paling banyak didiagnosis dengan tipe tidak terspesifikasi dengan 58,7% pasien anemia datang tanpa disertai penyakit lain dan 41,3% datang dengan penyakit penyerta.
Korelasi antara persentase lemak tubuh dan rasio lingkar pinggang-lingkar pinggul dengan kebugaran fisik pada mahasiswa Fakultas Kedokteran Universitas Mataram
Authors: Widiastuti Ida Ayu Eka , Priyambodo Seto , Buanayuda Gede Wira
Published: November 2020

Background: Body composition, is one of the factors that play a role in physical fitness. Body composition can be measured by calculating body fat percentage and waist-hip circumference ratio. Excessive body fat, usually will have a negative effect on physical fitness. The purpose of this study was to determine the correlation between body fat percentage and waist-hip circumference ratio with physical fitness.Methods: This study is a descriptive analytic study with a cross sectional design. The subjects were 82 medical students of Universitas Mataram who met the research criteria. Body fat percentage was measured by body composition monitor and physical fitness obtained from maximal oxygen uptake values (VO2max) that were calculated from the results of the Queen College Step Test. Data were analyzed by using the Pearson correlation test.Results: The results showed that the mean of body fat percentage, waist-hip circumference ratio, and VO2max were 28.3 kg/m2, 0.87 cm, and 37.7 ml/kg/minute, respectively. There was a significant correlation between body fat percentage and physical fitness (p = 0.02; r = -0.256) while there was no significant correlation between the waist-hip circumference ratio and physical fitness (p â‰¥ 0.05).Conclusion: The higher the body fat percentage, the lower the level of physical fitness.Â Latar belakang: Komposisi tubuh, merupakan salah satu faktor yang berperan dalam kebugaran fisik. Komposisi tubuh dapat diukur dengan menghitung persentase lemak tubuh dan rasio lingkar pinggang-lingkar pinggul. Seseorang yang memiliki kadar lemak tubuh yang berlebih, hampir selalu akan memberikan efek negatif terhadap kebugaran fisik. Tujuan penelitian ini adalah mengetahui korelasi antara persentase lemak tubuh dan rasio lingkar pinggang-lingkar pinggul dengan kebugaran fisik.Metode: Penelitian ini merupakan penelitian analitik deskriptif dengan desain cross sectional. Subjek penelitian adalah 82 mahasiswi Fakultas Kedokteran Universitas Mataram yang memenuhi kriteria penelitian. Dilakukan pengukuran persentase lemak tubuh dengan body composition monitor, pengukuran lingkar pinggang dan pinggul, dan nilai kebugaran fisik diperoleh dari nilai ambilan oksigen maksimal (VO2max) yang dihitung dari hasil Queen College Step Test. Data dianalisis dengan menggunakan uji korelasi Pearson.Hasil: Hasil penelitian menunjukkan bahwa rerata persentase lemak tubuh, rasio lingkar pinggang-lingkar pinggul, dan VO2max subjek masing-masing adalah 28,3 kg/m2, 0,87 cm, dan 37,7 ml/kg/menit. Terdapat korelasi bermakna antara persentase lemak tubuh dengan kebugaran fisik (p = 0,02; r = -0,256) sementara tidak terdapat korelasi bermakna antara rasio lingkar pinggang-lingkar pinggul dengan kebugaran fisik.Simpulan: Semakin tinggi persentase lemak tubuh maka semakin rendah tingkat kebugaran fisiknya.
The correlation of upper airway abnormalities with obstructive sleep apnea syndrome in young adult
Authors: Yunika Kanti , Mardalita Febby , Noventi Sefri , Marliyawati Dwi , Arifin Muhamad Thohar
Published: November 2020

Background: Obstructive Sleep Apnea Syndrome (OSAS) is one of sleep disorder characterised by repeated episodes of total obstruction in the upper airway system during sleep. The incidence of OSAS is estimated to be 1-10% of general population. OSAS can be affected by several risk factors. One of risk factor of OSAS is upper airway abnormalities. The study aims to find out the association between individual risk factor including septum deviation, nasal turbinate hypertrophy, tonsillar hypertrophy and mallampati score with the incidence of OSAS in young adults.Methods: Analytic observational research with case-control design was carried out on young adults aged 18-23 years in the city of Semarang during May - September 2018 grouped into OSAS and non-OSAS based on Polysomnography (PSG), then history and physical examination were performed. Statistical tests were using chi-square, Fisher's exact test, and logistic regression.Result: Total of 22 people were included in OSAS group and 22 were included in the control group. Bivariate analysis showed septum deviation (p= 0.005), tonsillar hypertrophy (p=0.015) and mallampati score (p<0.001) significantly related to the incidence of OSAS, whereas nasal turbinate hypertrophy was not associated with OSAS incident. The results of multivariate analysis found that BMI had an OR value of 133 (95% CI 12.726 â€“ 1390.002, p<0.001) independently associated with the occurrence of OSAS in young adults.Conclusion: Septal deviation, tonsillar hypertrophy, mallampati score are the risk factors for OSAS in young adults.
Efektivitas multi drug therapy pada transmisi morbus hansen transplasental
Authors: Widasmara Dhelya , Basuki Santosa , Florensia Dea , Setyagraha Ade , Prasetyorini Nugrahanti
Published: November 2020

Introduction:Â The evidence of transplancental transmission of Morbus Hansen (MH) in animal models is a challenge for MH treatment in pregnancy because it brings anxiety for patients and their fetuses.Â Case:Â A 31-year-old pregnant woman, first trimester, came with complaints of reddish numbness rash on her hands since 2 years ago. Dermatological examination showedÂ erythematousÂ plaque, multiple,Â well-defined, irregular borders withÂ hypoaesthesia. There were right and left ulnar nerve enlargement. Acid Fast Bacteria (AFB) fromÂ ear lobesÂ andÂ lesionÂ revealed Bacterial Index +2 and Morphological Index 10%.Â HistopathologicalÂ examination showedÂ grenÂ zone which indicate MH type BL. PatientÂ was diagnosedÂ with MH MultiÂ BasilerÂ (MB) onÂ G3P2002Ab000 and given MDT MHMB. Postpartum IgM and IgGÂ anti-PGL-1Â examination of cord blood and infant blood, alsoÂ PCRÂ examination of cord blood and amnion showed negative results. Histopathological examination found no AFB on the umbilical cord and placenta.Â Conclusion:Â MDT is effective in preventing transplacental transmission of MH from mother to fetus.
Acute fatty liver of pregnancy: a case report
Authors: Mahardika Putu Gede Agus Surya , Prabawa Aditya , Suardana Ketut
Published: November 2020

Introduction: Acute fatty liver of pregnancy (AFLP) is rare but potentially lethal complication. AFLP characterized by microvascular fatty infiltration of hepatocytes without any inflammation or necrosis.Case Presentation: A 37-year-old multigravida with 29 weeks period of gestation came with chief complains of acute jaundice, nausea, malaise and anorexia since 7 days ago. On examination, her eyes were icteric and her motor power was decreased on both extremities. Abdominal examination showed fetus in cephalic presentation with normal fetal heart rate. There was no opening and effacing of cervix. The ECG result showed prolonged QT interval. She had elevated liver enzyme, decreased renal function, electrolyte imbalance, hypoalbuminemia and hypercholesterolemia. Abdominal ultrasound was within normal limit. Patient was then assessed with differential diagnosed of AFLP, acute hepatitis and HELLP syndrome. She was treated conservatively with ferrous sulfate, high carbohydrate diet, KSR once daily, CDR once daily and Bisoprolol 1.25mg once daily. Â Three months later patient delivered a healthy baby boy via caesarian section due to premature rupture of membrane.Conclusion: Since AFLP is a medical and obstetric emergency, early recognition and prompt treatment improves both maternal and fetal survival.
Diabetes insipidus after suprasellar tumor surgery: case report
Authors: Bakhtiar Yuriz , Arifin Muhamad Thohar , Pratama Adrian , Bunyamin Jacob
Published: November 2020

Introduction: Diabetes insipidus (DI) is a rare water and electrolyte imbalance with hypovolemic hypernatremia characteristic (1:25.000) however can be potentially fatal if not well-anticipated and managed adequately. Brain tumors, either operated or not, may lead to DI (25%). Based on anatomical location, the suprasellar tumor may cause hypophyseal hormone dysfunction. Sellar region tumors can be classified into hypophyseal (90%) and non-hypophyseal (10%). Non-hypophyseal tumors with neurological deficits are more often causing hypophyseal hormone hyposecretion including DI. Sellar tubercle meningioma is one of the sellar region non-hypophyseal tumors which is often encountered and surgically managed. Worsening symptoms may become the surgical indication e.g. headache and visual disturbance.Â  Case: We are reporting two meningioma cases in Salatiga local hospital with almost similar tumor characteristics either size and frontal lobe location. Both cases were managed by similar transcranial tumor excision craniotomy. Their differences were in the presence of neurological manifestations and the degree of hypothalamic compression. One patient developed postoperative DI without thirst thus the clinical manifestation was polyuria which was closely monitored in the intensive ward. We were convinced that the DI incidence was affected by the tumor manifestation and location which can be assessed by computed tomography (CT) scans. Conclusion: The clinicians should anticipate the possibility of post craniotomy DI thus may provide adequate monitoring and management in patients developing postoperative DI.
Geoinformation-Cartographic Methods in Research of the Ecological and Economic Balance of the Territory
Authors: Khavanskaya Natalya , Vasilchenko Aleksandr
Published: November 2020

Estimation of the ecological and economic balance of the territory is important for developing a strategy for its rational use. A comprehensive account of the types of anthropogenic impact, the determination of the corresponding anthropogenic load, and, ultimately, the natural protection of the land is a source for forming recommendations and conducting activities to maintain sustainable development. Currently, in domestic science there are examples of such an assessment for areas with different types of specialization: agricultural, agro-industrial, industrial, recreational, which indicates the relevance of such studies. The aim of this work is to assess the environmental and economic balance of the territory of Krasnoarmeysky district of Saratov region using geoinformation mapping methods. The article successively describes the stages of assessing the environmental and economic balance: collecting, processing, decoding satellite images of Sentinel and Landsat; compiling a database of vector objects by the type of economic use; calculating the coefficients of anthropogenic load and natural protection of the territory based on statistical data obtained in the geoinformation system. According to the absolute tension coefficient (Ka), 3 clusters are identified in the territory of Krasnoarmeysky district: a cluster of medium intensity ECB (from 0.5 to 1), low (from 0 to 0.3) and lowered (from 0.3 to 0.5). Clusters of high degrees of tension are not allocated. According to the coefficient of relative tension (Ko), 2 clusters of low (from 0 to 2.5) and lowered (2.5–5) tension were identified. Clusters of high degrees of tension, as in the previous case, were not identified. According to the coefficient of natural security of the territory, 2 clusters are identified. According to the Kez coefficient, the northwestern part of the district refers to territories with average protection (0.43–0.49). The northeastern, central, and southern parts of the region belong to territories with increased (more than 0.5) security. Low (0–0.35) and lowered (0.36–0.42) natural security in the region is absent. The obtained values of the coefficients allow us to assess the economic development of the region as balanced.
Impact of a Combination of Different Technological Factors on the Effectiveness of the Processes of Ripping and Obtaining in vivo Caviar
Authors: Sariev Bekbol , Tumenov Arthur , Akhmetova Asel , Bakiyev Serik , Dzhunusov Ahmediyar
Published: November 2020

The objects of the study are the broodstocks of the siberian (Acipenser baerii) and Russian sturgeon (Acipenser gueldenstaedtii), sterlet (Acipenser ruthenus) and hybrids of rolek (Russian x Lena sturgeon), bester (beluga x sterlet), sturgeon caviar, pools for sturgeon fish producers, closed water supply installations, temperature regime for sturgeon rearing in conditions of installations with a closed water supply cycle. The purpose of the study is to improve the processing of sturgeon caviar obtained in vivo. The intravital method of obtaining sturgeon caviar compared to the traditional method allows saving the broodstock for subsequent reproduction. On the basis of the literature analysis, the influence of a combination of the main technological factors (temperature, hardener and de-sticking conditions) affecting the efficiency of maturation and production of intravital sturgeon caviar has been studied. The positive results of pre-spawning aging of sturgeon producers when grown under controlled conditions are obtained. The authors establish the temperature regime of pre-spawning aging of producers, which contributes to the effective maturation of intravital caviar. The parameters of the preservation of technological factors upon receipt of marketable sturgeon caviar were determined. The main technological factor for obtaining intravital caviar is the temperature regime of pre-spawning aging (temperature regime of artificial wintering) of producers. The studied individuals of sturgeon were tagged with special chips for identification and effective work in determining the stage of maturity and the subsequent production of caviar in vivo. The scope of applying the research results: fishery enterprises, research institutes of fisheries, small and medium-sized businesses, fish farmers
Can a High-Energy Diet Affect the Physical Fitness of Elite Athletes?
Authors: Yerzhanova Yeldana , Madiyeva Galya , Sabyrbek Zhanna , Dilmakhambetov Ermek , Milašius Kazys
Published: November 2020

The aim of the study was to investigate the effect of high energy diets, which were elaborated by the study authors, on the change of physical fitness of athletes of various sports. 90 athletes aged 17–30 years participated in the research. They were divided into three groups of 30 each. Our research has shown that prepared high-energy diets, used during 3 months in the preparatory period, per week-long training microcycles, had a greater positive effect on changes in the fitness of elite athletes of various sports compared to changes in the fitness of lower-performance athletes.
Prevalence and factors associated with mercury exposure in riverside communities in the Brazilian Western Amazon
Authors: Mendes Vanessa Alves , Santos Débora Aparecida da Silva , Farias Edson dos Santos , Carvalho Dario Pires de , Bastos Wanderley Rodrigues
Published: November 2020

ABSTRACT Objective: to verify mercury exposure prevalence and identify its possible associated factors in two riverside communities in the Madeira River basin of the Western Brazilian Amazon. Method: a cross-sectional study comprising 95 children and adolescents. Age cycle, school attendance, Bolsa Família, number of siblings, meals, fish consumption, height by age were measured. Binary logistic regression was used to verify relationships between mercury exposure and its possible associated factors. Results: the general prevalence of mercury exposure was 46.3%; children, 35.4%; and adolescents, 57.4%. Associated factors were fish consumption (aOR=1.84; 95%CI 1.56-2.16), age cycle (aOR=2.50; 95%CI 1.09-5.7), parasites (aOR=1.22; 95%CI 1.02-2.71), and short stature (aOR=1.32; 95%CI 1.05-2.02). Conclusion: mercury exposure prevalence in riverside children and adolescents was considered worrying, with association with fish consumption, adolescence, parasites, and short stature.
Avaliação participativa de um programa de prevenção e tratamento de Doenças Crônicas Não Transmissíveis
Authors: Leme Patricia Asfora Falabella , Campos Gastão Wagner de Sousa
Published: November 2020

RESUMO Trata-se da avaliação de um programa de prevenção e tratamento de Doenças Crônicas Não Transmissíveis (DCNT) oferecido à comunidade de uma universidade pública por ambulatório localizado em suas dependências. O processo avaliativo teve como objetivo apreender a dinâmica e compreender a forma de interação entre os atores envolvidos no cotidiano do programa, partindo do entendimento dos seus grupos de interesse, formados pela equipe, usuários, gestores e profissionais encaminhadores. Realizou-se pesquisa qualitativa de caráter participativo e com dimensão formativa para ampliar a possibilidade de aperfeiçoamento do programa pelos sujeitos envolvidos a partir de elementos oriundos de sua prática. A Avaliação de Quarta Geração de Guba e Lincoln e o Método Paideia de Campos foram norteadores metodológicos da pesquisa. A análise do material empírico foi agrupada em três núcleos temáticos: método de trabalho, equipe e gestão do programa. Constatou-se que uma escuta reflexiva dos profissionais é fator decisivo para ampliar a autonomia dos usuários e sua adesão terapêutica; a realização de grupos educativos no local de trabalho favoreceu a captação para tratamento e participação dos usuários, especialmente os do gênero masculino; e os encontros dos grupos possibilitam diversos ganhos objetivos e subjetivos, como a interação social entre pessoas de diferentes áreas da universidade.
Uma avaliação dos efeitos do PMAQ-AB nas internações por condições sensíveis à Atenção Básica
Authors: Soares César , Ramos Marília
Published: November 2020

RESUMO O objetivo deste artigo foi avaliar o efeito do Programa Nacional de Melhoria do Acesso e da Qualidade da Atenção Básica (PMAQ-AB) no acesso e na qualidade da Atenção Básica. As internações por condições sensíveis à Atenção Básica foram utilizadas como variável dependente e indicador indireto da qualidade e do acesso a esse nível de atenção. Utilizou-se o método quantitativo de estudo, tendo como unidade de análise todos os municípios brasileiros. O estudo se dividiu em duas fases: na primeira, foi realizada uma análise descritiva exploratória em série temporal sobre os municípios brasileiros, abrangendo o período de 2010 a 2014; e a segunda fase se caracterizou por avaliar o efeito do Programa, durante o mesmo período, no acesso e na qualidade da Atenção Básica, por meio da técnica estatística de regressão com dados de contagem. Os resultados, analisados por região, apontaram que o Programa está apresentando um efeito significativo na qualidade e no acesso da Atenção Básica, principalmente na região Nordeste. Este artigo surge como um importante informativo sobre as políticas de saúde no Brasil e, também, como um meio de instrumentalizar os gestores e os diversos atores envolvidos no desenvolvimento e discussão de um dos principais programas da Atenção Básica.
A benzedura nos territórios da Estratégia Saúde da Família: percepções de trabalhadores, usuários e benzedores
Authors: Assunção Luiza Maria de , Querino Rosimár Alves , Rodrigues Leiner Resende
Published: November 2020

RESUMO Vinculada à cultura brasileira, a benzedura é uma linguagem simbólica relevante e diferencial no papel de escuta e cuidado. O estudo teve por objetivo capturar os impactos da benzedura nos territórios da Estratégia Saúde da Família em município mineiro e analisar a relação entre os componentes do campo religioso e do campo médico-científico. Trata-se de estudo descritivo e exploratório, de natureza qualitativa, aprovado por comitê de ética. Realizaram-se 35 entrevistas semiestruturadas e empregou-se a análise temática para sua interpretação. Como aporte teórico, tomou-se o pensamento de Pierre Bourdieu sobre a disputa entre os campos de saber. Emergiram três categorias: Representações sobre a prática; Saúde e religiosidade/espiritualidade; Relações com a benzedura. A prática da benzedura é enxergada como parte da cultura. Destacou-se o seu impacto no resgate da dimensão subjetiva do cuidado, atuando na escuta, apoio, conforto, fortalecimento e desmedicalização. Consorciada à medicina, é ajuda adicional que enseja trabalhar a totalidade. A relação entre campo religioso e campo médico-científico por meio da benzedura propicia a diluição do conflito. Esta pesquisa propulsionará outros estudos na temática de terapias populares e produção de saúde e cuidado, bem como sobre a relação entre saúde e Religiosidade/Espiritualidade.
Especialização em Gestão do Trabalho e da Educação na Saúde: uma análise do programa nacional
Authors: Moysés Neuza Maria Nogueira , Vieira Ana Luiza Stiebler , Guimarães Tereza Cristina , Cardoso Andréa Lanzillotti
Published: November 2020

RESUMO Um dos propósitos do Componente III do Programa de Qualificação e Estruturação da Gestão do Trabalho e da Educação no SUS (ProgeSUS) foi o de oferecer cursos de Especialização em Gestão do Trabalho e da Educação na Saúde. Nesse sentido, o objetivo deste estudo foi o de analisar tal processo formativo no País, discutindo seus resultados e as perspectivas analíticas dos dirigentes nos diferentes níveis de coordenação a partir de análise qualitativa e quantitativa. Assim, valeu-se de registros da coordenação geral e da aplicação de questionário semiestruturado do qual se extraiu a análise sob a ótica dos coordenadores locais. No total, foram qualificados 1.471 gestores, sendo 557 no Nordeste, 301 no Norte, 236 no Sudeste, 224 no Centro-Oeste e 153 no Sul. Constatou-se a grande permanência dos alunos nos cargos de gestão; a aplicabilidade dos projetos de intervenção por eles elaborados; o eixo Gestão do Trabalho de maior evidência nas duas primeiras turmas, mas de igual interesse com a Gestão da Educação na terceira turma; e a necessidade de aprofundamento e aumento de carga horária em temas específicos nesses eixos. Essas informações constituem importantes subsídios para a formulação de políticas públicas que deem continuidade a esse processo de qualificação principalmente em vista da crescente terceirização dos vínculos dos trabalhadores da saúde e da gestão dos trabalhadores do SUS.