bluuebunny/crossref_metadata_2025 huggingface dataset:
Redeveloping the Sidki Field: Accident Becomes Opportunity
Authors: Denney Dennis
Published: February 2015

This article is a synopsis of paper SPE 36897, "Redeveloping the Sidki Field: How One Company Turned an Accident Into an Opportunity," by A.M. Ezzat, Gulf of Suez Petroleum Co., and T.J. Clark, Amoco Egypt Oil Co. originally presented at the 1996 SPE European Petroleum Conference, Milan, Italy 22-25 October.
Deeper Completions Really Lower Water/Oil Ratios!
Authors: Denney Dennis
Published: February 2015

This article is a synopsis of paper SPE 37763, "Deeper Completions Really Lower Water/Oil Ratios!" by E.E. Wadleigh, SPE, C.I. Paulson, SPE, and R.P. Stoltz, SPE, Marathon Oil Co. originally presented at the 1997 Middle East Oil Show and Conference, Manama, Bahrain, 15-18 March.
Los Angeles Basin: New Oil From Old Fields
Authors: Denney Dennis
Published: February 2015

This article is a synopsis of paper SPE 38330, "Los Angeles Basin, New Oil from Old Fields," by James M. Hill, CalTerra Energy LLC, originally presented at the 1997 SPE Western Regional Meeting, Long Beach, California, 25-27 June.
Remote Arctic Drilling Operations in Russia, Ardalin Field
Authors: JPT staff _
Published: February 2015

This article is a synopsis of paper SPE 36465, "Remote Arctic Drilling Operations in Russia, Case History of Ardalin Field Operations, Timan Pechora Basin," by E.M. Reyna, SPE, S. Nicholson, SPE, and S. Brady, SPE, Conoco Inc., originally presented at the SPE 1996 Annual Technical Conference and Exhibition held in Denver, Colorado, 6-9 October.
On-Line Process Optimization in a North Sea Field
Authors: JPT staff _
Published: February 2015

This article is a synopsis of paper SPE 38821, "On-Line Process Optimization in a North Sea Field," Y. Jalali, Schlumberger Wireline & Testing; W. Van Wassenhove, SE-Hyprotech, and C. Romano and R. Pickles, Schlumberger Wireline & Testing, scheduled for presentation at the 1997 SPE Annual Conference and Technical and Exhibition, San Antonio, Texas, 5-8 October.
Inciarte Talks About Technology, the Industry, and SPE
Authors: JPT staff _
Published: February 2015

President's interview - No abstract available.
Stopping a Water Cossflow in a Sour-Gas Producing Well
Authors: JPT staff _
Published: February 2015

This article is a synopsis of paper SPE 39396, "Stopping a Water Crossflow in a Sour-Gas Producer Well," by Y. Le Hello and P. Ghesquiere, Elf Aquitaine Production, and J. Woodruff, SPE, John Wight Co., originally presented at the 1998 IADC/SPE Drilling Conference, Dallas, 3-6 March.
Sand-Control Completion Design, Installation, and Performance in High-Rate Gas Wells
Authors: JPT staff _
Published: February 2015

This article is a synopsis of paper SPE 39432, "Sand-Control Completion Design, Installation, and Performance of High-Rate Gas Wells in the Jupiter Field," by R.C. Burton, SPE, and S.A. Boggan, SPE, Conoco Inc., originally presented at the 1998 SPE International Symposium on Formation Damage Control, Lafayette, Louisiana, 18-19 February.
Underbalanced Drilling in the Williston Basin
Authors: JPT staff _
Published: February 2015

This article is a synopsis of paper SPE 39924, "Underbalanced Drilling in the Williston Basin," by D.L. Purvis, SPE, and D.D. Smith, SPE, BJ Services, originally presented at the 1998 SPE Rocky Mountain Regional/Low Permeability Reservoirs Symposium, Denver, Colorado, 5-8 April.
Minimum Pseudocomponent Requirements for Compositional Thermal Simulation of Heavy Oil
Authors: Denney Dennis
Published: February 2015

This article is a synopsis of paper SPE 39640, "Minimum Pseudocomponent Requirements for Compositional Thermal Simulation of Heavy Oil," by C.S. Lolley, SPE, and W.C. Richardson, SPE, Texaco Group Inc.,originally presented at the 1998 SPE/DOE Improved Oil Recovery Symposium, Tulsa, Oklahoma, 19-22 April.
Increasing Heavy-Oil Production With Dual-String Technology
Authors: Denney Dennis
Published: February 2015

This article is a synopsis of paper SPE 46220, "Increasing Heavy-Oil Production Utilizing Dual-String New Technology," by B.L. Evans, SPE, B.L. Evans & Assocs. Inc., and G.M. Muth, SPE, Muth Pump LLC,originally presented at the 1998 SPE Western Regional Meeting, Bakersfield, California 10-13 May.
Minimal-Effort Time-Lapse 3D-Seismic Process
Authors: Denney Dennis
Published: February 2015

This article is a synopsis of paper OTC 8649, "Minimal-Effort Time-Lapse 3D (TL 3D) -Seismic Process," by Gary L. Kinsland and Louis M. Houston, U. of Southwestern Louisiana, originally presented at the 1998 Offshore Technology Conference, Houston, 4-7 May.
An Overview of the Genesis Development Project
Authors: Bybee Karen
Published: February 2015

This article is a synopsis of paper OTC 10796, "Genesis Development Project - Overview," by W.S. Young, B.C. May, and B.R. Varnado, SPE, Chevron North American E&P, originally presented at the 1999 Offshore Technology Conference, Houston, 3-6 May.
Best Completion Practices
Authors: Bybee Karen
Published: February 2015

This article is a synopsis of paper SPE 52810, "Best Completion Practices," by William Q. Dyson, SPE, Schlumberger Oilfield Services; Earl Coludrovich, SPE, Rachael Creech, and John C. Weldy, SPE, Texaco E&P; and Michael Fruge, SPE, and Marlon Guidry, Schlumberger Oilfield Services, originally presented at the 1999 SPE/IADC Drilling Conference, Amsterdam, 9-11 March.
Field Performance of New Perforating/Propellant Technology
Authors: Bybee Karen
Published: February 2015

This article is a synopsis of paper SPE 56469, "A Review of Field Performance of New Propellant/Perforating Technologies," by Jim Gilliat, Halliburton Energy Services Inc., Phillip M. Snider, SPE, Marathon Oil Co., and Robert Haney, HTH Technical Services Ltd., scheduled for presentation at the 1999 SPE Annual Technical Conference and Exhibition, Houston, 3-6 October.
Improving Capital Efficiency, A Case Study
Authors: Denney Dennis
Published: February 2015

This article is a synopsis of paper SPE 52850, "A Case Study in Improving Capital Efficiency," by K.L. Jackson, SPE, and R.M. Brennan, SPE, Conoco Inc.; R. Aranaga, Petroleos de Venezuela S.A.; R. Hawker, Remedy Resources Consultants Ltd.; and J.P. Montana, Schlumberger-IPM, originally presented at the 1999 SPE/IADC Drilling Conference, Amsterdam, 9-11 March.
Development of Heavy-Oil Fields on the U.K. Continental Shelf
Authors: Denney Dennis
Published: February 2015

This article is a synopsis of paper SPE 54623, "The Development of Heavy- Oil Fields in the U.K. Continental Shelf: Past, Present, and Future," by A.J. Jayasekera, SPE, U. K. Dept. of Trade and Industry, S.G. Goodyear, SPE, AEA Technology, originally presented at the 1999 SPE Western Regional Meeting, Anchorage, Alaska, 26-28 May.
Wormhole-Network Model of Cold Production in Heavy Oil
Authors: Denney Dennis
Published: February 2015

This article is a synopsis of paper SPE 54097, "A Wormhole-Network Model of Cold Production in Heavy Oil," by Jian- Yang Yuan, SPE, Bernard Tremblay, SPE, and Alex Babchin, Alberta Research Council, originally presented at the 1999 SPE International Thermal Operations and Heavy Oil Symposium, Bakersfield, California, 17-19 March.
Dehydration of Heavy Oil With Disk-Stack Centrifuges
Authors: Denney Dennis
Published: February 2015

This article is a synopsis of paper SPE 49119, "Dehydration of Heavy Crude Oil Using Disk-Stack Centrifuges," by Nimish Dhuldhoya, Texaco E&P Inc.; Mike Mileo, Texaco U.K.; and Mark Faucher, SPE, and Erik Sellman, SPE, Alfa Laval Separation Inc., prepared for the 1998 SPE Annual Technical Conference and Exhibition, New Orleans, 27-30 September.
Comments (October 2000)
Authors: Scott Dillon
Published: February 2015

Editor's column - No abstract available.
Maximizing Production With Permanent Downhole Sensors
Authors: Denney Dennis
Published: February 2015

This article is a synopsis of paper OTC 12153, "Maximizing Reservoir Production Using New Technologies for Permanent Continuous Downhole Sensors," by Michael J. Flecker, SPE, Stephen J. Thompson, and Colin S. McKay, SPE, Wood Group, and James L. Buchwalter, SPE, Gemini Solutions Inc., originally presented at the 2000 Offshore Technology Conference, Houston, 1-4 May.
JPT Forum (October 2000)
Authors: JPT staff _
Published: February 2015

JPT Forum - No abstract available.
Relevance (October 2001)
Authors: Holditch Stephen A.
Published: February 2015

President's column - No abstract available.
Overview: Completion Technology (October 2001)
Authors: Grigsby Tommy
Published: February 2015

Overview - No abstract available.
Field Trial of a Novel Multiphase Hydraulic Submersible Pump
Authors: Bybee Karen
Published: February 2015

This article is a synopsis of paper OTC 13197, "Field Trial and Subsequent Large-Scale Deployment of a Novel Multiphase Hydraulic Submersible Pump in the Captain Field," by W.G. Harden, SPE, Weir Pumps Ltd., and A.A. Downie, SPE, Texaco North Sea U.K. Co., originally presented at the 2001 Offshore Technology Conference, Houston, 30 April-3 May.
Networking Intelligent Subsea Completions
Authors: Denney Dennis
Published: February 2015

This article is a synopsis of paper SPE 71532, "Networking Intelligent Subsea Completions Using Industrial Standards," by Stephane Hiron, SPE, Schlumberger, originally presented at the 2001 SPE Annual Technical Conference and Exhibition, New Orleans, 30 September-3 October.
Intelligent Completion System Installed in the Gulf of Mexico
Authors: Denney Dennis
Published: February 2015

This article is a synopsis of paper OTC 11928, also presented as SPE 68218, "Case Study: First Intelligent Completion System Installed in the Gulf of Mexico," by V.B. Jackson, SPE, Halliburton Energy Services Inc., and T.R. Tips, SPE, Petroleum Engineering Services Inc., at the 2001 SPE Middle East Oil Show, Bahrain, 17-20 March.
Comments (October 1997)
Authors: Pike William J.
Published: February 2015

Editor's column - No abstract available.
Automatic Welding and Ultrasonic Inspection
Authors: Denney Dennis
Published: February 2015

This article is a synopsis of paper OTC 8496, "Automatic Welding and Ultrasonic Inspection for J-Lay of the Mars Tension-Leg-Platform Export Pipelines," by F. Kopp and G.G. Perkins, Shell Oil Products Co.; B.S. Laing, CRC Evans; G. Prentice, Shaw Pipeline Services; S.P. Springmann, J Ray McDermott; and D.M. Stevens, Babcock and Wilcox, originally presented at the 1997 Offshore Technology Conference, Houston, 5-8 May.
Reservoir Management of the Oseberg Field During 8 Years of Production
Authors: JPT staff _
Published: February 2015

This article is a synopsis of paper SPE 38555, "Reservoir Management of the Oseberg Field During 8 Years' Production," by Sigmund Sognesand, SPE, Norsk Hydro A/S, originally presented at the 1997 Offshore Europe Conference held in Aberdeen, 9-12 September.
Instrumented Drill Bit
Authors: Denney Dennis
Published: February 2015

This article is a synopsis of paper SPE 39341, "An Instrumented Bit: A Necessary Step to the Intelligent BHA," by Mike Smith, SPE, Evan Lowe, SPE, and Craig Coull, Baker Oil Tools, originally presented at the 1998 IADC/SPE Drilling Conference, Dallas, 3-6 March.
Production Management of Electrical Submersible Pumps
Authors: Denney Dennis
Published: February 2015

This article is a synopsis of paper SPE 49189, "Production Management of Electric Submersible Pumps Using Expert- System Technology," by Dan McLean, SPE, Kenonic Controls Ltd.; Roger Clay, Arco E&P Technology; and Wayne Gould, LTI Resource Management Inc., originally presented at the 1998 SPE Annual Technical Conference and Exhibition, New Orleans, 27-30 September.
Induced-Stress Diversion: A Novel Approach to Fracturing Multiple-Pay Sands
Authors: JPT staff _
Published: February 2015

This article is a synopsis of paper SPE 39945, "Induced-Stress Diversion: A Novel Approach to Fracturing Multiple-Pay Sands of the NBU Field, Uintah Co., Utah," by T.W. Hewett, SPE, Coastal O&G, and C.J. Spence, SPE, Dowell, originally presented at the 1998 SPE Rocky Mountain Regional/Low Permeability Reservoirs Symposium, Denver, Colorado, 5-8 April.
Impact of Formation Damage and Completion Impairment on Horizontal-Well Productivity
Authors: JPT staff _
Published: February 2015

This article is a synopsis of paper SPE 49097, "The Impact of Formation Damage and Completion Impairment on Horizontal-Well Productivity," by R.C. Burton, SPE, and R.M. Hodge, SPE, Conoco Inc., originally presented at the 1998 SPE Annual Technical Conference and Exhibition, New Orleans, 27-30 September.
Reliability Analysis of Permanent Downhole Monitoring Systems
Authors: Denney Dennis
Published: February 2015

This article is a synopsis of paper OTC 10945, "Reliability Analysis of Permanent Downhole Monitoring Systems," by S.J.C.H.M. van Gisbergen, Shell Intl. Deepwater Services B.V., and A.A.H. Vandeweijer, Shell Intl. E&P B.V., originally presented at the 1999 Offshore Technology Conference, Houston, 3-6 May.
Electrical Coiled-Tubing Drilling: A Smarter Drilling System
Authors: Denney Dennis
Published: February 2015

This article is a synopsis of paper SPE 52791, "Electric Coiled-Tubing Drilling: A Smarter CT-Drilling System," by D.R. Turner, SPE, XL Technology Ltd.; T.W.R. Harris, SPE, Shell Expro U.K. Ltd.; M. Slater, SPE, Amoco Corp. E&P Technology; M.A. Yuratich, SPE, TSL Technology Ltd.; and P.F. Head, SPE, XL Technology Ltd., originally presented at the 1999 SPE/IADC Drilling Conference, Amsterdam, 9-11 March.
Neural Networks for Predictive Control of Drilling Dynamics
Authors: Denney Dennis
Published: February 2015

This article is a synopsis of paper SPE 56442, "Application of Neural Networks for Predictive Control in Drilling Dynamics," by D. Dashevskiy, U. of Houston, and V. Dubinsky, SPE, and J.D. Macpherson, SPE, Baker Hughes Inteq, originally presented at the 1999 SPE Annual Technical Conference and Exhibition, Houston, 3-6 October.
Practical Examples of Well-Test Problems
Authors: Bybee Karen
Published: February 2015

This article is a synopsis of paper SPE 52202, "Some Practical Examples of Difficult Well-Test Problems," by D.D. Charles, SPE, Cardinal Services, originally presented at the 1999 SPE Midcontinent Operations Symposium, Oklahoma City, Oklahoma, 28-31 March.
Pinpointing Fluid Entries in Producing Wells
Authors: Bybee Karen
Published: February 2015

This article is a synopsis of paper SPE 53249, "Pinpointing Fluid Entries in Producing Wells," by Justin Rounce, SPE, and Chris Lenn, SPE, Schlumberger Technical Services, and Gerard Catala, Schlumberger Riboud Product Center, originally presented at the 1999 SPE Middle East Oil Show, Bahrain, 20-23 February.
Selective Production of Horizontal Openhole Completions
Authors: Bybee Karen
Published: February 2015

This article is a synopsis of paper SPE 55618, "Selective Production of Horizontal Openhole Completions Using ECP and Sliding-Sleeve Technology," by J.J. Constantine, SPE, Baker Oil Tools, originally presented at the 1999 SPE Rocky Mountain Regional Meeting, Gillette, Wyoming, 15-18 May.
Journey: (November 2000)
Authors: Bernard Bruce E.
Published: February 2015

President's column - No abstract available.
Technology Improves Underbalanced Operations
Authors: Finston Liz
Published: February 2015

Technology Update - No abstract available.
Openhole Memory-Logging and Wireless-Conveyance Systems for Horizontal Wells
Authors: Denney Dennis
Published: February 2015

This article is a synopsis of paper SPE/PS-CIM 65461, "The Role of Openhole Memory-Logging and Wireless-Conveyance Systems in the Evaluation of Horizontal Wells," by Peter A.S. Elkington, SPE, Reeves Technologies Ltd., prepared for presentation at the 2000 SPE/Petroleum Society of CIM International Conference on Horizontal Well Technology, Calgary, 6-8 November.
Saturation Mapping From 4D Seismic Data in the Statfjord Field
Authors: Denney Dennis
Published: February 2015

This article is a synopsis of paper OTC 12100, "Saturation Mapping From 4D Seismic Data in the Statfjord Field," by P.M. Doyen, D.E. Psaila and D. Astratti, Western Geophysical, and L.B. Kvamme and N.F. Al- Najjar, Statoil A/S, originally presented at the 2000 Offshore Technology Conference, Houston, 1-4 May.
Drill-In Fluid for a Sour-Gas Naturally Fractured Reservoir
Authors: Bybee Karen
Published: February 2015

This article is a synopsis of paper SPE 59051, "Drill-In Fluid Selection for High-Temperature, Sour-Gas, Naturally Fractured Reservoirs," by Z. Krilov, SPE, D. Domitrovic, SPE, T. Soric, and M. Gracanin, INA-Naftaplin Oil Co., originally presented at the 2000 SPE International Petroleum Conference and Exhibition in Mexico, Villahermosa, Mexico, 1-3 February.
Overview: Reservoir Performance (November 2000)
Authors: O'Brien William J.
Published: February 2015

Overview - No abstract available.
Integrated Flow Modeling: The Fusion of Geophysics and Reservoir Engineering
Authors: Denney Dennis
Published: February 2015

This article is a synopsis of paper SPE 63137, "Integrated Flow Modeling: The Fusion of Geophysics and Reservoir Engineering," by Theodore A. Pagano, SPE, Texaco E&P Inc., John R. Fanchi, SPE, and Thomas L. Davis, Colorado School of Mines, originally presented at the 2000 SPE Annual Technical Conference and Exhibition, Dallas, 1-4 October.
Relevance (November 2001)
Authors: Holditch Stephen A.
Published: February 2015

President's column - No abstract available.
Predicting Permeability in Carbonates for Interwell Permeability Mapping
Authors: Denney Dennis
Published: February 2015

This article is a synopsis of paper SPE 71336, "Predicting Permeability From Well Logs in Carbonates With a Link to Geology for Interwell Permeability Mapping," by James W. Jennings Jr., SPE, and F. Jerry Lucia, SPE, Bureau of Economic Geology, U. of Texas, originally presented at the 2001 SPE Annual Technical Conference and Exhibition, New Orleans, 30 September-3 October.
Adding Value to Impedance Models Through Sequence Stratigraphy
Authors: Denney Dennis
Published: February 2015

This article is a synopsis of paper SPE 71350, "Adding Value to Impedance Models Through Sequence Stratigraphy," by Z. Marzuki, SPE, Petronas Carigali, and M.S. Sams and D. Atkins, Jason Geosystems, originally presented at the 2001 SPE Annual Technical Conference and Exhibition, New Orleans, 30 September-3 October.
Multiphase Flow in Subsea Flowline Systems During Emergency Shutdown
Authors: Bybee Karen
Published: February 2015

This article is a synopsis of paper SPE 69418, "Dynamic Processes of Multiphase Flow in Subsea Flowline/ Riser Systems During ESD Valve Shutdown," by Y. Doreen Chin, SPE, J.P. Kenny Inc., and Zeng-Gang Xu, SPE, Scandpower A/S, originally presented at the 2001 SPE Latin American and Caribbean Petroleum Engineering Conference, Buenos Aires, 25-28 March.
A Drillpipe Riser System for the Roncador Field
Authors: Bybee Karen
Published: February 2015

This article is a synopsis of paper OTC 13256, "Installation of Subsea Trees in Roncador Field at 1800 m Water Depth Using the Drillpipe Riser," by J.R.F. Moreira, Petrobras, and T.E. Johansen, SPE, FMC-KOS, originally presented at the 2001 Offshore Technology Conference, Houston, 30 April-3 May.
Monitoring Synthetic-Based Fluids for Oil Contamination
Authors: JPT staff _
Published: February 2015

This article is a synopsis of paper SPE 37906, "On-site and Off-site Monitoring of Synthetic-Based Drilling Fluids for Oil Contamination," by M. Churan, J.E. Candler, and M. Freeman, M-I Drilling Fluids LLC, originally presented at the 1997 SPE/EPA Exploration and Production Environmental Conference held in Dallas, 3-5 March.
Control of Microbiological Activity in Biopolymer-Based Drilling Muds
Authors: JPT staff _
Published: February 2015

This article is a synopsis of paper SPE 39285, "Control of Microbiological Activity in Biopolymer-Based Drilling Muds," by A.M. Ezzat, SPE, H.R. Rosser, and A.A. Al-Humam, Saudi Aramco, scheduled for presentation at the 1997 SPE Middle East Drilling Technology Conference to be held in Bahrain, 23-25 November.
Joint Inversion of Resistivity Logs: Limits and Possibilities
Authors: Denney Dennis
Published: February 2015

This article is a synopsis of paper OTC 8567, "Joint Inversion of Resistivity Logs: Limits and Possibilities," by K.M. Strack, SPE, A.G. Mezzatesta, SPE, and M.A. Frenkel, Western Atlas Logging Services, originally presented at the 1997 Offshore Technology Conference, Houston, 5-8 May.
Logging-Information System Visualization
Authors: Denney Dennis
Published: February 2015

This article is a synopsis of paper SPE 37713, "Visualization of a Logging-Information System Through Object-Oriented Modeling," by K. Suryanarayana, ONGC-Schlumberger Wireline Research Centre; P.K. Cherukupalli, ONGC; and T.V.S. Rao, HLS India Ltd., originally presented at the 1997 SPE Middle East Oil Show, Bahrain, 15-18 March.
Pulsed-Neutron Three-Phase-Holdup Measurements in Horizontal Wells
Authors: Denney Dennis
Published: February 2015

This article is a synopsis of paper SPE 38704, "Field-Test Results of a Three-Phase-Holdup Measurement in Horizontal Wells Using a Pulsed-Neutron Source," by B.A. Roscoe, SPE, Schlumberger-Doll Research originally presented at the 1997 SPE Annual Technical Conference and Exhibition, San Antonio, Texas, 5-8 October.
Wireline Well-Tractor Technology for Horizontal-Well Logging and Intervention
Authors: Denney Dennis
Published: February 2015

This article is a synopsis of paper SPE 38757, "The Application of New Wireline Well-Tractor Technology to Horizontal Well Logging and Intervention: A Review of Field Experience in the North Sea," by Gerald McInally, Maritime Well Service, and Jorgen Hallundbaek, SPE, Welltec Inc., originally presented at the 1997 SPE Annual Technical Conference and Exhibition, San Antonio, Texas, 5-8 October.
Speaking Up (November 1998)
Authors: Sprunt Eve S.
Published: February 2015

Guest editorial - No abstract available.
Exact Spherical-Flow Solution with Storage for Early-Time-Test Interpretation
Authors: Denney Dennis
Published: February 2015

This article is a synopsis of paper SPE 39768, "New, Exact Spherical-Flow Solution With Storage for Early-Time-Test Interpretation With Applications to Early-Evaluation Drillstem and Wireline Formation Testing," by Mark A. Proett, SPE, and Wilson C. Chin, SPE, Halliburton Energy Services, originally presented at the 1998 SPE Permian Basin Oil and Gas Recovery Conference, Midland, Texas, 25-27 March.
Evolutionary Environmental Management of Drilling Discharges
Authors: JPT staff _
Published: February 2015

This article is a synopsis of paper SPE 46617, "Evolutionary Environmental Management of Drilling Discharges: Results Without Cost Penalty," by G. Hanni, SPE, J. Hartley, R. Munro, and A. Skullerud, Amoco, originally presented at the 1998 SPE International Conference on Health, Safety and Environment in Oil and Gas Exploration and Production, Caracas, 7-10 June.
Wellbore-Stability Predictions Using a Modified Lade Criterion
Authors: JPT staff _
Published: February 2015

This article is a synopsis of paper SPE 47251, "Wellbore-Stability Predictions Using a Modified Lade Criterion," by R.T. Ewy, SPE, Chevron Petroleum Technology Co., originally presented at the 1998 SPE/ISRM Eurock, Trondheim, Norway, 8-10 July.
Two SEM Techniques To Investigate Reservoir-Rock Wettability
Authors: Robin Michel , Combes Rossana , Cuiec Louis
Published: February 2015

E&P Exchange - SPE 52526
Author's Reply to Discussion of Modeling the U.S. Oil Industry: How Much Oil is Left?
Authors: Taylor Paul J.
Published: February 2015

Author's reply - No abstract available.
Author's Reply to Discussion of Worldwide Petroleum-Liquid Supply and Demand
Authors: Mamora D.D. , Startzman R.A. , Wattenbarger R.A. , Al-Jarri A.S.
Published: February 2015

Author's reply - No abstract available.
Towards 2001 (November 1999)
Authors: Colligan John A.
Published: February 2015

President's column - No abstract available.
Speaking Up (November 1999)
Authors: Sprunt Eve S.
Published: February 2015

Guest editorial - No abstract available.
Simulation Cell for Differential-Pressure Sticking
Authors: Bybee Karen
Published: February 2015

This article is a synopsis of paper SPE 52816, "Downhole Simulation Cell for Measurement of Lubricity and Differential-Pressure Sticking," by P. Isambourg, Elf Exploration Production; S. Ottesen, SPE, Mobil Technology Co.; S. Benaissa, SPE, Baker Hughes Inteq; and J. Marti, ENI Tarbes, originally presented at the 1999 SPE/IADC Drilling Conference, Amsterdam, 9-11 March.
Development Planning With Low-Invasion Coring and Outcrop Studies
Authors: Denney Dennis
Published: February 2015

This article is a synopsis of paper SPE 53718, "Application of Low Invasion Coring and Outcrop Studies to Reservoir Development Planning for the Villano Field," by J. J. Rathmell, SPE, Arco Technology and Operations Services; Laura K. Atkins, Arco Dubai Inc.; and James G. Kralik, SPE, Arco Technology and Operations Services, originally presented at the 1999 Latin American and Caribbean Petroleum Engineering Conference, 21-23 April, Caracas.
Journey: (December 2000)
Authors: Bernard Bruce E.
Published: February 2015

President's column - No abstract available.
Comments (December 2000)
Authors: Scott Dillon
Published: February 2015

Editor's column - No abstract available.
ATCE 2000
Authors: JPT staff _
Published: February 2015

Conference review - No abstract available.
Improving PDC Performance, Prudhoe Bay, Alaska
Authors: Bybee Karen
Published: February 2015

This article is a synopsis of paper SPE 59226, "Design at the Customer Interface: Practicalities of Improving Established Benchmark Performance, Prudhoe Bay, Alaska," by J.P. Lewis, SPE, Fairweather Technologies; D.M. Stone, SPE, Arco; G. Hecht, Sperry Sun; and L. Eichman, Security DBS, originally presented at the 2000 IADC/SPE Drilling Conference, New Orleans, 23-25 February.
Overview: Reservoir/ Asset Management (December 2000)
Authors: Penney Richard K.
Published: February 2015

Overview - No abstract available.
Managing Operating Costs With a Risk- and Economic-Evaluation Tool
Authors: Denney Dennis
Published: February 2015

This article is a synopsis of paper SPE 64448, "A Risk- and Economic-Evaluation Tool for Management of Operating Costs," by Helen E. Harvey, SPE, and Dale P. Gration, Woodside Energy Ltd., and Stephen Martin, IGL Engineering Pty. Ltd., originally presented at the 2000 SPE Asia Pacific Oil and Gas Conference and Exhibition, Brisbane, Australia, 16-18 October.
Optimizing Blake Field Development
Authors: Bybee Karen
Published: February 2015

This article is a synopsis of paper SPE 64714, "Optimizing the Development of Blake Field Under Tough Economic and Environmental Conditions," by K.E. Du, SPE, S. Pai, J. Brown, R.M. Moore, and M. Simmons, BG Intl., originally presented at the 2000 SPE International Oil and Gas Conference and Exhibition in China, Beijing, 7-10 November.
Microearthquake Monitoring for Reservoir Management
Authors: Denney Dennis
Published: February 2015

This article is a synopsis of paper SPE 63131, "The Role of Microearthquake Monitoring in Hydrocarbon- Reservoir Management," by A. Jupe, SPE, R. Jones, S. Wilson and J. Cowles, SPE, ABB Offshore Systems Ltd., originally presented at the 2000 SPE Annual Technical Conference and Exhibition, Dallas, 1-4 October.
Relevance (December 2001)
Authors: Holditch Stephen A.
Published: February 2015

President's column - No abstract available.
Q&A with Anibal R. Martinez
Authors: Martinez Anibal R.
Published: February 2015

Q&A - No abstract available.
Combined Propellant/Perforating Improves Production
Authors: Bybee Karen
Published: February 2015

This article is a synopsis of paper SPE 68101, "A Unique Approach to Enhancing Production From Depleted, Highly Laminated Sand Reservoirs Using a Combined Propellant/ Perforating Technique," by H. El- Bermawy, SPE, Agiba Petroleum Co., and H. El-Assal, Halliburton Energy Services, originally presented at the 2001 SPE Middle East Oil Show, Bahrain, 17-20 March.
Integrating 3D Geological Data Into a Fluid-Flow Model
Authors: Denney Dennis
Published: February 2015

This article is a synopsis of paper SPE 68646, "Integrating 3D Geological Data Into Fluid-Flow Model Improves Reservoir Management Plan: Serang Field Case Study," by Sukerim Waryan, SPE, D.T. Vo, SPE, Jim Stites, SPE, and Mark Swanson, Unocal Indonesia Co., originally presented at the 2001 SPE Asia Pacific Oil and Gas Conference and Exhibition, Jakarta, 17-19 April.
Real Options and Probabilistic Economics: Bridging the Gap
Authors: Denney Dennis
Published: February 2015

This article is a synopsis of paper SPE 71408, "Real Options and Probabilistic Economics: Bridging the Gap," by H.T. Hooper III, SPE, and S.R. Rutherford, SPE, Anadarko Petroleum Corp., originally presented at the 2001 SPE Annual Technical Conference and Exhibition, New Orleans, 30 September-3 October.
Overview: Bit Technology (December 2001)
Authors: Miller Brian
Published: February 2015

Overview - No abstract available.
Dialog (December 2001)
Authors: Demirmen Ferruh , Coca Benjamin , Murtha James A.
Published: February 2015

Dialog - Discussion/Reply. No abstract available.
Optimized Bit and Motor Usage Offshore Qatar
Authors: JPT staff _
Published: February 2015

This article is a synopsis of paper SPE 39249, "Optimized Bit and Motor Usage Offshore Qatar," by Michael A. Simpson, SPE, Ahmed Fakhro, SPE, and Ahmed Al-Bakri, Qatar General Petroleum Corp., by originally presented at the 1997 SPE/IADC Middle East Drilling Technology Conference, held in Manama, Bahrain, 23-25 November.
Bicenter-Bit Technology for Undergauge-Hole Problems
Authors: JPT staff _
Published: February 2015

This article is a synopsis of paper SPE 39247, "Utilization of Bicenter-Bit Technology To Solve Undergauge-Hole Problems in the Dukhan Field," by A. Shehata, SPE and M.A. Simpson, SPE, Qatar General Petroleum Corp., originally presented at the 1997 SPE/IADC Middle East Drilling Technology Conference held in Manama, Bahrain, 23-25 November.
Reciprocal Productivity Index for Oilwell and Gaswell Evaluation
Authors: Denney Dennis
Published: February 2015

This article is a synopsis of paper SPE 37409, "Oil and Gas Well Evaluation Using the Reciprocal Productivity Index Method," by J.W. Crafton, SPE, Performance Sciences Inc., originally presented at the 1997 SPE Production Operations Symposium, Oklahoma City, Oklahoma, 9-11 March.
Short- and Long-Term Management of El Furrial Field, Venezuela
Authors: Denney Dennis
Published: February 2015

This article is a synopsis of paper SPE 38781, "Short- and Long-Term Management of El Furrial Field, Venezuela," by Rodolfo Colmenares, Lagoven, S.A., and R.W. Smith, Integrated Reservoir Management Inc., originally presented at the 1997 SPE Annual Technical Conference and Exhibition, San Antonio, Texas, 5-8 October.
Cooperative Approach Yields Better Understanding of PDC-Bit Performance
Authors: JPT staff _
Published: February 2015

This article is a synopsis of paper SPE 39313, "Cooperative Approach to Drilling Optimization Yields Better Understanding of PDC-Bit Performance in North Sea Program," by R.J. Begbie, SPE, Amerada Hess Ltd., and B.E. Miller, SPE, Hughes Christensen, originally presented at the 1998 IADC/SPE Drilling Conference, Dallas, 3-6 March.
Real-Time Downhole-Vibration Monitoring Prevents Bit Damage
Authors: JPT staff _
Published: February 2015

This article is a synopsis of paper SPE 39314, "Revised Drilling Practices, VSS-MWD Tool Successfully Addresses Catastrophic Bit/Drillstring Vibrations," by N.E. Shuttleworth and E.J. van Kerkoerle, NAM Pro-Star; D.R. Folmer, Hughes Christensen Co.; and N. Foekema, SPE, Baker Hughes Inteq, originally presented at the IADC/SPE Drilling Conference, Dallas, 3-6 March.
Shock-Subassembly Performance Tests
Authors: JPT staff _
Published: February 2015

This article is a synopsis of paper SPE 39323, "Shock-Sub Performance Tests," by T.M. Warren, SPE, and J.H. Oster, Amoco E&P Technology Group; L.A. Sinor, SPE, Hughes Christensen; and D.C.K. Chen, SPE, Sperry-Sun, originally presented at the 1998 IADC/SPE Drilling Conference, Dallas, 3-6 March.
Steel-Body PDC-Bit Technology Improves Bit Performance
Authors: JPT staff _
Published: February 2015

This article is a synopsis of paper SPE 47815, "Steel-Body-PDC-Bit Technology Demonstrates Performance Improvements," by L.M. Smith, SPE, Security DBS; V.P. Perrin, SPE, Chevron Petroleum Technology; and R. Delwiche, SPE, Security DBS, originally presented at the 1998 IADC/SPE Asia Pacific Drilling Technology, Jakarta, 7-9 September.
PDC-Bit Performance in Deep Shales
Authors: JPT staff _
Published: February 2015

This article is a synopsis of paper SPE 47814 "Addressing the Problem of PDC Bit Performance in Deep Shales," by J.R. Smith, SPE, Louisiana State U., originally presented at the 1998 IADC/SPE Asia Pacific Drilling Technology, Jakarta, 7-9 September.
Uncertainty Analysis with Gradient Information
Authors: Denney Dennis
Published: February 2015

This article is a synopsis of paper SPE 48997, "Uncertainty Analysis in Predictive Reservoir Simulation Using Gradient Information," by O.J. Lepine and R.C. Bissell, SPE, Elf Exploration U.K.; S.I. Aanonsen, SPE, Norsk Hydro; I. Pallister, SPE, GeoQuest RT; and J.W. Barker, SPE, Elf Exploration U.K., prepared for the 1998 SPE Annual Technical Conference and Exhibition, New Orleans, 27-30 September.
Use of Effective Permeabilities Fracture Characterization to Simulate Naturally Fractured Reservoirs
Authors: Denney Dennis
Published: February 2015

This article is a synopsis of paper SPE 48999, "Field Simulation of Naturally Fractured Reservoirs Using Effective Permeabilities Derived from Realistic Fracture Characterization," by C.L. Jensen, SPE, S.H. Lee, SPE, W.J. Milliken, SPE, J. Kamath, SPE, W. Narr, and H. Wu, Chevron Petroleum Technology Co., and J.P. Davies, SPE, Chevron North America E&P Co., prepared for the 1998 SPE Annual Technical Conference and Exhibition, New Orleans, 27-30 September.
Economic Advantages of a New Straight-Hole Drilling Device
Authors: Bybee Karen
Published: February 2015

This article is a synopsis of paper SPE 56444, "Outstanding Economic Advantages Based on New Straight- Hole Drilling Device Proven in Various Oilfield Locations," by A. Calderoni, SPE, Eni-Agip, and A. Savini, J. Treviranus, and J. Oppelt, SPE, Baker Hughes Inteq, originally presented at the 1999 SPE Annual Technical Conference and Exhibition, Houston, 3-6 October.
Dual-Torque Concept Enhances PDC-Bit Efficiency in Directionaland Horizontal-Drilling Programs
Authors: Bybee Karen
Published: February 2015

This article is a synopsis of paper SPE 52879, "Dual-Torque Concept Enhances PDC-Bit Efficiency in Directional and Horizontal Drilling Programs," by Graham Mensa- Wilmot, SPE, GeoDiamond; Tony Krepp, SPE, K&M Technology Group; and Ita Stephen, SPE, Mobil Producing, originally presented at the 1999 SPE/IADC Drilling Conference, Amsterdam, 9-11 March.
Rotary Drilling the Khuff Formation With PDC Bits
Authors: Bybee Karen
Published: February 2015

This article is a synopsis of paper SPE 53341, "Rotary Drilling US-Khuff Formation With PDC Bits," by Moh'd Salman and H. El Raggal, Adma-Opco, originally presented at the 1999 Middle East Oil Show, Bahrain, 20-23 February.
Slimhole-Dual-Body-Bit Optimization
Authors: Bybee Karen
Published: February 2015

This article is a synopsis of paper SPE 54595, "Optimization of Slimhole Dual- Body Bits by Experiments and Computational Fluid Dynamics," by J.T.V. de Sousa, M. Prohaska, and A. Bencic, SPE, U. of Leoben, and K.K. Millheim, SPE, U. of Oklahoma, originally presented at the 1999 SPE Western Regional Meeting, Anchorage, 26-28 May.
Data Integration for Reservoir Characterization and Monitoring
Authors: Denney Dennis
Published: February 2015

This article is a synopsis of paper OTC 10741, "The Hibernia Oil Field: Integration of Geophysical, Geological, and Production Data Into Reservoir Characterization and Monitoring," by Larry J. Sydora, Hibernia Management and Development Co. Ltd., originally presented at the 1999 Offshore Technology Conference, Houston, 3-6 May.
Sequence Stratigraphy in Reservoir Simulation
Authors: Denney Dennis
Published: February 2015

This article is a synopsis of paper SPE 51892, "Incorporating Sequence Stratigraphy in Reservoir Simulation: an Integrated Study of the Meren E-01/MR- 05 Sands in the Niger Delta," by Gerald Cook, SPE, Adwait Chawathe, SPE, David Larue, and Henry Legarre, Chevron Petroleum Technology Co., and Ebenezer Ajayi, SPE, Chevron Nigeria Ltd., originally presented at the 1999 SPE Reservoir Simulation Symposium, Houston, 14-17 February.
Water and Nitrogen Productivity of Maize under Semiarid Environments
Authors: Hammad Hafiz Mohkum , Ahmad Ashfaq , Abbas Farhat , Farhad Wajid , Cordoba Bernardo Chaves , Hoogenboom Gerrit
Published: February 2015

Irrigated agriculture is a facing shortage of water and N in semiarid environments where these inputs are limiting factors for crop production. Experiments were conducted to optimize the water and N requirements for maize (Zea mays L.) under semiarid environmental conditions. Crop physiological and agronomics characteristics were evaluated for three irrigation regimes and five N fertilizer levels during 2009 and 2010. The experiments were conducted in a split‐plot design by triplicating water regimes in the main plots and N levels in the subplots. Total dry matter production and crop growth rate increased with an increase in the N application rate up to 300 kg ha−1 for all irrigation regimes. In contrast, maximum grain yield was achieved with application of 250 kg N ha−1. Polynomial analysis (third order) showed that 275 kg N ha−1 was optimum for grain yield at normal irrigation. Higher amounts of irrigation and N significantly increased water use efficiency (WUE). Since optimal N rates for maximum grain yield was 250 kg ha−1 with 525 mm irrigation water ha−1 during both growing seasons, this may be considered in formulating good agricultural practices for the soil and weather conditions resembling those of this study.
Yield and Forage Value of a Dual‐Purpose bmr‐12 Sorghum Hybrid
Authors: Yerka Melinda K. , Watson Andrea , Toy J. J. , Erickson Galen , Pedersen Jeffrey F. , Mitchell Rob
Published: February 2015

Grain sorghum [Sorghum bicolor (L.) Moench] is an important crop for rainfed production systems with 2.7 million ha grown in the United States in 2013. The brown‐midrib (bmr) mutations, especially bmr‐12, have resulted in low stover lignin and high fiber digestibility without reducing grain yield in some sorghum lines. However, the effect of the bmr trait on beef cattle (Bos taurus) performance when grazing crop residue is unknown. Our objectives were to validate previous small‐plot results reporting no grain yield difference between near‐isogenic bmr‐12 (BMR) and wild‐type control (CON) A Wheatland × R Tx430 sorghum hybrids in a field‐scale experiment and to determine if BMR stover enhances beef production in a grazing experiment. Four replicated paddocks (2.3 ha) were planted in 2006 and 2008 near Mead, NE. Crossbred yearling steers (240 ± 17 kg hd−1) grazed (2.6 steers ha−1) paddocks following grain harvest for 72 d in 2006 and 61 d in 2008. Forage was sampled 4, 30, and 60 d after grazing began. Grain yield of BMR was 6% less (P = 0.01) than CON with no difference in stover neutral detergent fiber (NDF) content, but BMR stover had higher in vitro NDF digestibility (IVNDFD) (31%; P < 0.0001), steer average daily gain (ADG; 0.18 kg hd−1 d−1; P = 0.001), and body weight (BW) gain (29 kg ha−1; P = 0.002), resulting in an estimated increase in net return of $133.84 ha−1 due to BMR. Results suggest that the A Wheatland × R Tx430 bmr‐12 hybrid is an effective dual‐purpose sorghum crop for both grain and beef production.
The Impact of Vaccination on Influenza-Related Respiratory Failure and Mortality in Hospitalized Elderly Patients Over the 2013-2014 Season
Authors: Joshi Manish , Chandra Deepak , Mittadodla Penchala , Bartter Thaddeus
Published: February 2015

Background :

Seasonal Influenza (“the flu”) is a respiratory illness caused by influenza viruses. Yearly influenza vaccination is considered to be protective against illness and/or severity of illness and is recommended by CDC for all individuals > 6 months of age. However, the effectiveness of influenza vaccine in older individuals has come under question.

Objectives :

To describe the clinical characteristics and treatment outcomes of patients admitted to an academic tertiary care Veterans Administration hospital with influenza during the 2013-2014 influenza season and determine the impact, if any, of prior influenza vaccination upon patient outcomes.

Methods :

Medical electronic records were searched for all patients admitted to the Little Rock Veterans Administration Hospital with proven influenza during the 2013-2014 influenza season. Cohorts of vaccinated and non-vaccinated patients were then compared to determine the impact of prior influenza vaccination upon respiratory-failure and mortality.

Results :

Seventy patients met selection criteria. Mean age was 66 years. Sixty-four (91%) patients had at least one underlying co-morbid condition; these conditions included COPD, congestive heart failure, diabetes, and cancer. 60/70 (85%) tested positive for Influenza A, and 43 tested positive for H1N1. Oseltamivir was initiated in 55 (78%) patients. Forty-four percent of the patients had been vaccinated. When separated by vaccination status, those who had been vaccinated had higher rates of ICU admission, need for mechanical or non-invasive ventilation, and mortality. All but mortality reached statistical significance.

Conclusion :

The data suggest that there was no protective effect from prior vaccination in preventing hospital admission, respiratory failure, and mortality in this population of older men admitted to the hospital with influenza.
Effect of gantacurium on evoked laryngospasm and duration of apnea in anesthetized healthy cats
Authors: Martin-Flores Manuel , Cheetham Jonathan , Campoy Luis , Sakai Daniel M. , Heerdt Paul M. , Gleed Robin D.
Published: February 2015

OBJECTIVE To evaluate whether the ultrashort-acting neuromuscular blocking agent gantacurium can be used to blunt evoked laryngospasm in anesthetized cats and to determine the duration of apnea without hemoglobin desaturation.

ANIMALS 8 healthy adult domestic shorthair cats.

PROCEDURES Each cat was anesthetized with dexmedetomidine and propofol, instrumented with a laryngeal mask, and allowed to breathe spontaneously (fraction of inspired oxygen, 1.0). The larynx was stimulated by spraying sterile water (0.3 mL) at the rima glottidis; a fiberscope placed in the laryngeal mask airway was used to detect evoked laryngospasm. Laryngeal stimulation was performed at baseline; after IV administration of gantacurium at doses of 0.1, 0.3, and 0.5 mg/kg; and after the effects of the last dose of gantacurium had terminated. Duration of apnea and hemoglobin oxygen saturation (measured by means of pulse oximetry) after each laryngeal stimulation were recorded. Neuromuscular block was monitored throughout the experiment by means of acceleromyography on a pelvic limb.

RESULTS Laryngospasm was elicited in all cats at baseline, after administration of 0.1mg of gantacurium/kg, and after the effects of the last dose of gantacurium had terminated. The 0.3 and 0.5 mg/kg doses of gantacurium abolished laryngospasm in 3 and 8 cats, respectively, and induced complete neuromuscular block measured at the pelvic limb; the mean ± SE duration of apnea was 2 ± 1 minutes and 3 ± 1.5 minutes, respectively. Hemoglobin oxygen saturation did not decrease significantly after administration of any dose of gantacurium.

CONCLUSIONS AND CLINICAL RELEVANCE Gantacurium may reduce tracheal intubation-associated morbidity in cats breathing oxygen.
Essai d'égo-histoire
Authors: Lévesque Andrée
Published: February 2015

Résumé :

Cet essai d'égo-histoire suit une trajectoire qui débute avec un goût précoce pour l'histoire, et se poursuit avec l'étude de la géographie, puis de l'histoire : histoire du socialisme et du mouvement ouvrier puis histoire des femmes, en Europe, au Québec et au Canada. Andrée Lévesque a eu la chance de pouvoir concilier son engagement politique et social avec son intérêt pour l'histoire, de lier l'action à la recherche. Ses propres travaux privilégient les sujets à la marge de la politique et de la société, pour révéler les rapports de pouvoir à différents moments du xxe siècle.
Critical Assessment of Land Use Land Cover Dynamics Using Multi-Temporal Satellite Images
Authors: Mondal Md. , Sharma Nayan , Kappas Martin , Garg P.
Published: February 2015

An attempt has been made to assess the dynamics of land use land cover change (LULCC) in the study area. LANDSAT-5 TM, IRS-1C LISS III, IRS-P6 LISS III images of 1987, 1997 and 2007, respectively, were digitally classified for land use land cover (LULC) mapping. The dynamics of LULCC critically analyzed for the two time periods 1987–1997 and 1997–2007. The LULCC analyzed in terms of quantity of change and allocation of change. Relative changes; gross gains, gross losses and persistence; net change and swap changes of LULC of the study area examined carefully. The study provided a better understanding of the LULCC pattern. The total change during (1987–1997) was 68.40% and during (1997–2007) was 80.12%. Major exchanges of areas are in between degraded forest and built up land followed by dense forest and degraded forest. Others dominant systematic transitions are: degraded forest to built up land; dense forest to degraded forest; agricultural land to built up; degraded forest to land with or without scrub; land with or without scrub to built up; and in between river and sandy area. The transformation from forest to built up land especially built-up area constitutes a large percentage of the total landscape. The direct beneficiaries of this research will include resource managers and regional planners as well as others scientific community.
The Role of Genotypes That Modify the Toxicity of Chemical Mutagens in the Risk for Myeloproliferative Neoplasms
Authors: Gross-Davis Carol , Heavner Karyn , Frank Arthur , Newschaffer Craig , Klotz Judith , Santella Regina , Burstyn Igor
Published: February 2015

Background: The etiology of myeloproliferative neoplasms (MPN) (polycythemia vera; essential thrombocythemia; primary myelofibrosis) is unknown, however they are associated with a somatic mutation—JAK2 V617F—suggesting a potential role for environmental mutagens. Methods: We conducted a population-based case-control study in three rural Pennsylvania counties of persons born 1921–1968 and residing in the area between 2000–2008. Twenty seven MPN cases and 292 controls were recruited through random digit dialing. Subjects were genotyped and odds ratios estimated for a select set of polymorphisms in environmentally sensitive genes that might implicate specific environmental mutagens if found to be associated with a disease. Results: The presence of NAT2 slow acetylator genotype, and CYP1A2, GSTA1, and GSTM3 variants were associated with an average 3–5 fold increased risk. Conclusions: Exposures, such as to aromatic compounds, whose toxicity is modified by genotypes associated with outcome in our analysis may play a role in the environmental etiology of MPNs.
Synthesis and Disinfection Effect of the Pyridine-4-aldoxime Based Salts
Authors: Marek Jan , Malinak David , Dolezal Rafael , Soukup Ondrej , Pasdiorova Marketa , Dolezal Martin , Kuca Kamil
Published: February 2015

A set of new quaternary ammonium compounds based on pyridine-4-aldoxime was synthesized, characterized with analytical data (NMR, EA, HPLC, MS) and tested for in vitro antimicrobial activity (antibacterial, antifungal) and cytotoxicity. Quaternary pyridinium-4-aldoxime salts with length of alkyl side chain from C8 to C20 and belonging to the group of cationic surfactants were investigated in this work. An HPLC experimental protocol for characterization of mixtures of all homologues has been found. Antimicrobial evaluation found that yeast-type fungi were most sensitive towards C14 and C16 analogues, whereas the C16 analogue was completely ineffective against filamentous fungi. Antibacterial assessment showed versatility of C14 and relatively high efficacy of C16 against G+ strains and C14 against G− strains. Notably, none of the studied compounds exceeded the efficacy and versatility of the benzalkonium C12 analogue, and benzalkonium analogues also exhibited lower cytotoxicity in the cell viability assay.