bluuebunny/crossref_metadata_2025 huggingface dataset:
MALE BREAST CANCER TREATMENT: CLINICAL CASE
Authors: KAIDAROVA D. , DMITRENKO M. , CHICHUA N. , SMAGULOVA K. , ABDRAKHMANOV R. , KALDARBEKOV S. , KALMEN P.
Published: September 2022

Relevance: Male breast cancer (BC) is one of the rarest diseases and accounts for 1/100 of detected BC cases in both sexes. About
30-70% of breast cancer cases in men develop against the background of gynecomastia, particularly its nodular form. The biology of this
disease differs in men, but the approaches to diagnostics and treatment are usually extrapolated from those used in women.
This study aimed to demonstrate the results of each stage of a male patient with BC diagnostics and treatment.
Methods: The article presents a clinical case of a male patient diagnosed with «Cancer in the right breast St III (T4NxM0),
Edematous-infiltrative form with an intraductal component, upper outer localization. Immunohistochemically luminal subtype B
without Her2neu expression». The data from literary sources and clinical protocols on the male BC diagnosis and treatment were
also reviewed.
Results: The patient received four courses of preoperative chemotherapy according to the “AС” scheme Doxorubicin 60 mg/m2
(CD 120 mg) + Cyclophosphamide 600 mg/m2
(CD 1200 mg). Intermediate instrumental and laboratory control and assessing the
response to treatment according to the RECIST criteria are planned.
Conclusion: The presented rare clinical case of male BC demonstrates that diagnostics and treatment at the initial stage remain
the same as recommended for women. Identical preoperative and adjuvant chemotherapy regimens are applicable. Since most male
BC express estrogen receptors, endocrine therapy such as tamoxifen is the kind of routine for adjuvant male BC treatment. This article
describes the performed laboratory and instrumental diagnostics and preoperative chemotherapy treatment of the patient. The second
part of the publication will present the results of the performed chemotherapy and surgical treatment and recommendations issued to
the patient.
MEDULLOBLASTOMA IN A 16-YEAR-OLD PATIENT: A CLINICAL CASE
Authors: KOPOCHKINA С. , GONCHAROVA A. , DUSHIMOVA Z. , BYKOVSKAYA A. , TOKHMOLDAYEVA K. , ZHARASPAYEVA M.
Published: September 2022

Relevance: Brain tumors are children’s most common solid tumors, with medulloblastomas accounting for almost 20%. The Electronic
Registry of Oncological Patients of the Republic of Kazakhstan (RK) reports 27 morphologically verified cases of medulloblastoma in
2021, 18 of them in children (66.6%).
The aim was to show the feasibility of conducting a molecular genetic study to clarify the diagnosis of brain tumors using a clinical
case as an example.
Methods: The article describes a clinical case of a patient with medulloblastoma. The examinations included computed tomography
of the brain, magnetic resonance imaging of the brain, and pathomorphological revision with an immunohistochemical examination of
postoperative material.
Results: The patient was admitted to the Center of Pediatric Oncology of “Kazakh Institute of Oncology and Radiology” JSC
(Almaty, Kazakhstan) with a referral morphological diagnosis of “Ependymoma of the cerebellar vermis with compression of the
4th ventricle. Grade II. Condition – after ventricular operitoneostomy on the left side (14.11.2021), after microsurgical removal of
the tumor (07.12.2021). 2nd clinical group.” Because of the atypical localization of the formation, a pathomorphological review with
an immunohistochemical study of the postoperative material was carried out. Conclusion: the morphological picture and immunophenotype correspond to desmoplastic/nodular medulloblastoma, grade IV. ICD-O code 9471/3. The treatment tactics were revised
based on morphological data.
Conclusion: Medulloblastoma is a highly malignant tumor with an aggressive course. Choosing the right treatment tactics depends on a timely, accurate diagnosis, which makes the diagnosis a critical link in the patient management algorithm. In addition, it
requires conducting a morphological and immunohistochemical examination. According to the 5th version of the 2021 WHO classification of CNS tumors, a molecular genetic study is required to accurately determine the morphological structure of the tumor and
achieve a better response to therapy. In addition, it necessitates a revision of the relevant clinical guidelines adopted in the Republic
of Kazakhstan
STERNUM TUMOR SURGICAL TREATMENT METHOD: A CLINICAL CASE
Authors: PYSSANOVA Zh.
Published: September 2022

Relevance: Sarcomas are relatively rare tumors. They make up 1% of all malignant neoplasms in adults, of which about 10-15% appear in the chest wall. Unlike primary tumors, metastatic bone tumors occur 2-4 times more often, while the sternum is affected in 9% of
all metastatic bone lesions. A review of the literature and analysis of patients with chest wall tumors showed that surgical treatment might
be the best option for primary and secondary chest wall tumors.
Chondrosarcoma is the most common primary chest bone sarcoma and originates from the anterior segment of the ribs, less often from
the sternum, scapula, or clavicle.
The study aimed to present the outcome of a sternum sarcoma surgical treatment with a simultaneous reconstruction of an extensive
postoperative defect at the Kazakh Institute of Oncology and Radiology (Almaty, Kazakhstan).
Methods: The article reviews the literature on the treatment of chest wall tumors and describes a clinical case of a patient with
chondrosarcoma of the sternum. After subtotal resection of the sternum 2-3 cm away from the tumor margins, the patient underwent
reconstructive plastic surgery. Synthetic material was used to stabilize the chest wall, prevent paradoxical breathing, and replace
the defect.
Results: No recurrence of the primary process was registered after radical removal of the sternum tumor with the simultaneous reconstruction of the defect with synthetic material. Given the prevalence of the tumor, intraoperative suturing of the subclavian vein was
performed, which led to vein thrombosis in the postoperative period.
Conclusions: Early recognition and radical removal with adequate margins are essential to successful sternum tumor treatment. Complete excision with broadly negative microscopic margins at the first operation is paramount since local recurrence increases the risk of
systemic metastasis and death. Thus, standard guidelines are required to ensure the proper treatment of chest wall sarcomas.
TOTAL VAGINECTOMY FOR RECURRENT GYNECOLOGICAL CANCER: A SERIES OF CLINICAL CASES
Authors: SATANOVA A. , KAIDAROVA D. , KUKUBASSOV E. , BERTLEUOV O. , KALDYBEKOV D. , BOLATBEKOVA R.
Published: September 2022

Relevance: Treating vaginal recurrence of gynecological cancer remains a complex clinical problem. Surgery is an effective and relatively safe strategy for these cases. Vaginectomy is a method of surgical treatment of gynecological cancer local recurrence. Although vaginectomy is considered an effective treatment for a vaginal recurrence of cervical, ovarian, or endometrial cancers, only a few published
reports of vaginal resections have been found. In most cases, vaginal resections were performed by vaginal and/or/or open access. Several
reports on laparoscopic vaginal resection for recurrence in gynecological cancer were found.
The aim was to study the effectiveness of vaginectomy in recurrent gynecological cancer.
Methods: Clinical cases of seven patients after vaginectomy were analyzed.
Results: The patients were 42 to 62 years (median – 53 years). The duration of the operation varied from 240 to 480 minutes
(median – 317 min), the volume of blood loss was from 90 to 220 ml (median 140 ml), and resection margins were negative in all
cases. A ureteral catheter was installed in 2 cases. The Foley catheter was removed after ten days on average (1-11 days). The
patients stayed in the hospital for 7-14 days (median – 7 days). No intraoperative complications were registered. All patients after
vaginectomy are alive.
Conclusion: Vaginal recurrence is the most common local recurrence in gynecological cancer, and there is no consensus regarding
its treatment tactics. Although this article is somewhat limited in the number of patients, our results show the efficacy of vaginectomy in
recurrent vaginal gynecological cancer
BURNOUT SYNDROME AMONG MEDICAL PROFESSIONALS: LITERATURE REVIEW
Authors: ZHUMANBAYEVA Zh. , КRYKPAEVA A. , SERIKBAEV A. , RAKHMATULLINA N. , AITMURZINOVA G. , SEITKABYLOV A.
Published: September 2022

Relevance: Burnout syndrome in medical staff is a sensitive topic of health care, as this condition can directly affect treatment and care,

that is, the patient’s satisfaction with the medical service and the psychological state of the medical staff as a whole. Burnout syndrome

includes several risk factors that can directly affect the spread of this syndrome. Thus, the psychological state of medical personnel and the

prevention of burnout syndrome is an important healthcare aspect.

The purpose of the study was to review the literature on the spread, risk factors, and prevention of burnout syndrome in medical staff.

Methods: The research for papers was made using the PubMed, Cochrane Library, Medscape, CINAHL, and Google Scholar search

engines, e-Library.ru, and CyberLeninka electronic libraries. Inclusion criteria: search depth of 10 years (2012-2022), original articles,

literature reviews, meta-analyses, and systematic reviews, and open-access full-text articles in English and Russian. Exclusion criteria:

low-quality articles not meeting the search criteria or containing unclear information and conclusions, reports, abstracts, and newspaper

articles. In total, the review included 46 articles.

Results: The literature review showed that burnout syndrome among medical staff is spreading every year and requires high-quality

prevention methods.

Conclusion: The literature review showed that emotional burnout syndrome among medical workers is a global problem and has

become one of the most noticeable issues in healthcare. From the point of risk factors, professional factors rank first, followed by social,

physiological, and other factors. The reviewed foreign and domestic publications insufficiently study the burnout syndrome prevention

measures and their efficacy.
Epidemiology, Classification and Management of Zygomatic Fractures Among Children
Authors: Bukhsh Ayman , Majrashi Faisal , Almutairi Abdullah , Alraqibah Mohammed , Alnasser Noor , Alheddeni Morad , Hamidah Sameer , Almarwani Talal , Alonazi Rahaf , Al-Mousa Abeer , Alnami Abdulrahman
Published: September 2022

The zygomatic bone, which includes the lateral and inferior orbital rims as well as the malar eminence, comprises the lateral part of the midface, giving it width and projection. Zygomatic arch fractures account for 10% to 15% of all facial fractures and are commonly caused by a direct blow to the face. Zygomatic fractures are most caused by blunt trauma. Paediatric zygomatic fractures are a rare complication in the continuum of craniofacial injuries that cosmetic and reconstructive surgeons deal with. The combination between etiology, force of damage, and stage of craniofacial development determines the location and distribution of facial fractures in children. The purpose of this research is to review the available information about the epidemiology, classification and management of zygomatic fractures in children. Although facial fractures especially zygomatic fractures in children are quite uncommon and rare, appropriate screening and diagnosis, as well as prompt treatment, are necessary to avoid consequences. Surgeons face tremendous hurdles when dealing with facial trauma associated with serious injuries, as there is a functional and aesthetic impact on the growing children, as well as a financial and emotional burden on the patient and family. The early management of zygomatic fractures in children, like any trauma, detects situations that require rapid treatment to avoid life-threatening consequences. Paediatric zygomatic fractures are quite uncommon due to the specific anatomic, physiologic, social, and environmental aspects that accompany craniofacial growth however the literature data is lacking and quite scarce, more epidemiological studies targeting age group of children are needed.
Indications, Efficacy, Safety and Complications of Retrograde Intrarenal Surgery
Authors: Tayeb Mustafa , Alghamdi Mohammed , Alhazmi Mohammed , Alqurashi Enad , Alsubaie Abdulhadi , Alotaibi Awnallah , Mobaraki Ahmed , Abdulmajeed Abdulaziz , Alamri Abdulrahim , Alamri Abdulrahman , Aboukhshaba Ahmad
Published: September 2022

Kidney stones are one of the most prevalent disorders associated with significant morbidity. Initially the renal stones were treated with open surgery but with the advancements in technology shift towards the minimally invasive therapeutic procedures is observed. Recent technological advances in the field of urology have led to more prevalent use of retrograde intrarenal surgery for the treatment of urolithiasis. The introduction of new laser systems and advanced flexible ureteroscopy with a small ureteroscope have contributed to increase in indications for intrarenal surgery to include not only larger kidney stones > 2 cm, but also urothelial carcinoma of the upper urinary tract, urethra, and idiopathic renal haematuria. Retrograde intrarenal surgery is one of the most safe and effective minimally invasive technique which due to its positive outcomes and less rate of complications has gained much popularity in the field of urology with the passage of time. The purpose of this research is to review the available information about the indications, efficacy, safety and complications of retrograde intrarenal surgery. Retrograde intrarenal renal surgery is indicated in various cases including lower calyx stones and stones greater than 2 cm among many others. Evidence from the literature suggests retrograde intrarenal surgery as quite a safe and effective method with high success rate and minimum and minor complications being reported. In future more randomized trial studies on retrograde intrarenal surgery can however significantly contribute to literature and benefit clinical practice also
Prevalence of Short Stature Among Children Aged 5-12 Years Old in Taif City, Saudi Arabia
Authors: Al Ghamdi Ahmed , AlGhamdi Mansour , Al Manjoomi Raid , Al Homyani Doua , Mahboob Mohra , Jimenez Joan , Al Juaid Hanoof , Al Malky Matar , AlThobaiti Saleh , Dagreri Narges
Published: September 2022

Background: Short stature is one of the most common and frequent diagnosis in children investigated by pediatricians in everyday practice. The aim of this study was to analyse the prevalence of short stature in children between 5 to 12 years of age in Taif City, Saudi Arabia. Methods: This is a cross-sectional study performed on children where height was measured for all participants and an average of three measurements was recorded. A questionnaire on various parameters influencing short stature such as height of parents, birth history, history of illness, family history of short stature and chronic illness were completed by the children’s guardian. Results: Out of 314 children, 188 children were male (59.87%) and 126 were female (40.13%). The overall prevalence rate of short stature was 33.68%. Regarding male participants, 29 were identified as short stature (15.43%) compared to 23 females that were identified as short stature (18.25%). One male and two females with short stature were born prematurely. The most common etiology for short stature was familial short stature with 40.8% followed by malnutrition which was 24.2%. Growth hormone deficiency was the most common endocrinological cause for short stature (9.7%) followed by hypothyroidism (7.6%). Chronic kidney disease was the most common non-endocrinological cause (3.4%). Meanwhile, other disorders were found such as celiac disease (0.5%) and Turner’s Syndrome (0.3%).
Duma i pożądanie – badanie emocji w ocenie produktów przez użytkowników z wykorzystaniem zaadaptowanej wersji narzędzia badawczego PrEmo
Authors: Ludwiczak Beata
Published: September 2022

Wzornictwo jest dziedziną o dwoistej naturze, obejmującą zarówno aspekty techniczne produktów, jak i estetyczne. Współcześnie, przy szerokim zakresie zadań podejmowanych przez projektantów, estetykę produktów trafniej jest interpretować jako doświadczenie estetyczne, które jest ściśle związane z emocjami generowanymi przez artefakty, a także ich wizerunki w reklamie, marketingu czy kulturze. Możliwość badania emocji wzbudzanych przez produkty może być użyteczna dla przedstawicieli wielu dziedzin, również dla projektantów.
Niniejszy artykuł prezentuje badanie empiryczne emocji, jakie wzbudza wygląd produktów z wykorzystaniem zaadaptowanej wersji narzędzia o nazwie PrEmo, przeprowadzone podczas kursu magisterskiego dla studentów wzornictwa w Akademii Sztuk Pięknych im. E. Gepperta we Wrocławiu. Tekst składa się z dwóch części – wstępu stanowiącego przegląd literatury oraz raportu z badania empirycznego.
Trzy przestrzenie wyobrażone inspirowane krajobrazem
Authors: Łapińska Joanna
Published: September 2022

Artykuł stanowi kontynuację serii prezentującej efekty badań naukowo-artystycznych dotyczących odczytywania przestrzeni dostrzeżonych w naturze. Teoretyczne rozważania przedstawione w poprzednich numerach zostały przeniesione na działania twórcze – projekty architektury wnętrz wcielające zasady biofilii, które powstały w wyniku zastosowania trzech metod intertekstualnej interpretacji natury: naśladowania formy (nawiązania do wyglądu zewnętrznego), naśladowania zasady działania oraz zaprzeczenia (jednoczesnego nawiązania i podważenia cech immanentnych obiektowi inspiracji). Zaprezentowana została droga projektowa uwzględniająca różne środki artystyczne. Przestrzenie odnalezione w krajobrazie stanowią instalacje, które mogą stać się podstawą projektu architektury wnętrza mieszkalnego, jak również użytkowego.
Peregrynacje... Określanie przestrzeni (własnej)*
Authors: Gibała-Kapecka Beata , Dettloff Anna
Published: September 2022

Podjęta problematyka dotyczy rozważań czy nadal istnieje potrzeba semantycznego odznaczania przestrzeni, obiektów i miejsc. Czy na pewno forma i materia muszą być wypełnione treściami, zawierać komunikaty w warstwie znaczeniowej? W świetle rozpatrywanej kształtowanej architektonicznej przestrzeni szans nakładamy wyobrażenia, interpretacje bez roszczeń do bycia jedynie słusznymi. W konfrontacji i dialogu wytracają się raz jedne, innym razem drugie właściwości przestrzeni, obiektów i miejsc, bo te pozostają zależne od czasu, także tego, w jakim znajduje się dany odbiorca.
Japonia – niepokoje czy sztuka wyciszenia?
Authors: Czudak Małgorzata
Published: September 2022

Celem artykułu jest przybliżenie wpływu, jaki na projektantów mody i designu z Azji, a dokładniej z Japonii, wywiera wykształcona przez Japończyków estetyka. Czy twórcze niepokoje znajdują wizualizację w projektach, czy sztuka wyciszenia, filozofia i estetyka wykształcona od pokoleń daje impuls do działania? Analiza założeń i pojęć z tej dziedziny pozwoliła na wybranie tych – według autora najważniejszych – pojęć, które determinują działania japońskich twórców. Każdy aspekt życia Japończyków ma na celu wywołanie efektu estetycznego.
W tekście omówione zostały takie określenia charakterystyczne dla estetyki japońskiej jak shibui, wabi sabi, iki. Poznanie tych zagadnień pozwala głębiej zrozumieć sens działań i filozofię projektantów, ich podejście do piękna, życia, śmierci. Autor opisuje zachwyt Japończyków nad kruchością i ulotnością, niedoskonałością i niedopowiedzeniami. Zrozumienie tych podstawowych pojęć daje wiedzę, która pozwala zrozumieć filozofię twórców designu na przykładzie twórczości Naoto Fukasawy, studia projektowego Nendo czy marki MUJI. Omówione zostały również sylwetki projektantów mody mających wkład w rozwój tego obszaru: Rei Kawakubo, Isseya Miyake, Yoshija Yamamto. Zapoznanie się z przedstawionymi w tekście zagadnieniami pozwala lepiej i głębiej zrozumieć filozofię twórczości japońskich projektantów.
Współczesne technologie a nowa perspektywa pojmowania celów projektowych.
Authors: Sobolewska Dominika
Published: September 2022

Interakcja jest dziś powszechnie znanym terminem, który na polu architektury i projektowania często kojarzony jest z pojedynczymi, kazuistycznymi urządzeniami technologicznymi czy też systemowymi rozwiązaniami usprawniającymi funkcjonalność użytkowanych przez nas przedmiotów. Stosunkowo rzadko jednak myśli się o interaktywności w większej skali terytorialnej, jako o dynamicznej przestrzeni dialogu mającej określony wpływ na społeczeństwo.
Mimo iż projektowanie interaktywne coraz mocniej ugruntowuje swoją pozycję w coraz to nowych sektorach działalności ludzkiej (wystawiennictwo, sztuka interaktywna, rozrywka, edukacja,), to relatywnie niewiele uwagi we współczesnej debacie społecznej poświęca się jego misji socjokulturowej.
Niniejszy artykuł jest próbą zdefiniowania roli i celów projektowania przestrzennego, wykorzystującego nowe technologie pod takim właśnie kątem. Główna idea oscyluje tu wokół doniosłości zastosowania tego typu rozwiązań w obszarze budowania zdrowych relacji społecznych i nowych trendów kulturowych.
Ekranowe okna – akademickie badania architektonicznej roli bezszwowych ekranów we wnętrzach publicznych
Authors: Jakubicki Bartosz , Wojtyła - Młynarczyk Agata
Published: September 2022

Multidyscyplinarność w projektowaniu wnętrz jest już nie tylko powszedniością, ale i koniecznością. Technologia cyfrowa będąca w codziennym użyciu społeczeństwa informacyjnego wpływa na sposób projektowania współczesnych wnętrz, ich odbiór mentalny oraz stawiane im wymagania estetyczno-funkcjonalne. Trudno dziś znaleźć wnętrze bez ekranu lub wyświetlacza, a te stają się coraz częściej świadomym narzędziem, środkiem kreacji w rękach projektantów wnętrz, szczególnie w zakresie przestrzeni publicznych. Artykuł ten przedstawia badania akademickie i studenckie projekty dotyczące problemu celowego wykorzystania ekranów jako współczesnych okien, zaangażowania ich do gry kompozycyjnej, w której ekrany stanowią otwory do innej przestrzeni w znaczeniu architektonicznym. Otwierają bryły i transmitują zewnętrze. Poruszony został także aspekt zmian percepcji społecznej wnętrza przy zastosowaniu połaci ekranów bezszwowych, emitujących obrazy dostosowane do kategorii wnętrza, poszerzających możliwości użytkowe oraz kreacyjne pomieszczeń. Zaprezentowanych zostało 10 projektów studenckich, stworzonych w ramach jednego projektu badawczego, proponujących odmienne zastosowania ekranów bezszwowych, określając ich nowe role w tworzeniu konkretnych przestrzeni publicznych. Ten zbiór pomysłów stanowi propozycję zmiany w traktowaniu ekranów jako elementów wyposażenia wnętrza, na rzecz traktowania ich jako jednej z integralnych części architektonicznej kompozycji.
Holy Instruction, Demonic Deceit, and the Body: A Translation of Jean Gerson’s Sermon on Angels (Collatio de Angelis)
Authors: Fogleman Andrew
Published: September 2022

Jean Gerson (1363–1429), theologian and chancellor of the University of Paris, is well known for his writings on the “discernment of spirits.” Gerson’s Sermon on Angels (1392), translated here, provides his earliest thoughts on judging the supernatural. In it, Gerson explains how angels instruct and demons seduce the cognitive faculties of men and women. The related challenges of authenticating true religious visions and exposing demonic or naturalistic fakes led Gerson to doubt some would-be visionaries and even question the role of visionary evidence in canonization trials. While these doubts are also articulated in his later, better-known treatises on discernment, he describes how he came to those conclusions here, in an exploration of the physiology of visions and demonic deception. Gerson’s sermon highlights the delicate role that cognition plays in assessing supernatural experiences and helps to explain the criticisms of ascetic practices included in his later treatises on spiritual discernment.
Frequency of Diabetic Retinopathy in already diagnosed cases of Diabetes Mellitus- A single center Experience
Authors: Chachar Aijaz Zeeshan Khan , Tanveer Khushbakht , Arshad Sana , Nazir Humaira , Adam Mohamed Abdullahi , Asif Mohsin
Published: September 2022

Background: Patients with diabetes mellitus ends up in many complications and retinopathy is one of the microvascular complications of this metabolic disease. Aim: To conclude the frequency of diabetic retinopathy in previously diagnosed patients of diabetes. Methods: Cross Sectional study was conducted in General Medicine Department, Fatima Memorial Hospital, Lahore. This study was conducted from 16th January 2021 to 16th July 2021. A total of 171 patients in both male and female with diabetes mellitus were involved in the study. All patients undertook fundoscopy to look for diabetic retinopathy in department of medicine. Non-probability consecutive sampling technique was used. Results: As per this study age series from 30 to 75 years with mean age of 51.099±6.19 years, mean duration of diabetes 9.304±3.60 years and mean weight was 87.713±7.63 Kg. Male patients were 64.9% and females were 35.1%. Diabetic retinopathy was seen in 36.8%. Conclusion: There is increase in prevalence of diabetic retinopathy with rise in period of diabetes mellitus. Keywords: Diabetes mellitus, Diabetic retinopathy, Duration of diabetes
Different Causes and its Association in Children with Cerebral Palsy
Authors: Rafique Akkad , Saeed Kamran , Ali Mehtab , Baluch Tauseef Ahmed , Bajwa Hafiz Ahmed Fayyaz , Gillani Syed Faraz Ul Hassan Shah
Published: September 2022

Aim: To assess the different causes and their association of cerebral palsy in children. Methods: We conducted this cross-sectional survey using consecutive sampling technique at the orthopedic surgery department Mayo hospital, Lahore from October 2011 to November. The sample size was 200 children of all age groups, on history and clinical examination who were diagnosed with cerebral palsy were included in the study and children or their parents refused to participate in the study were excluded. Results: Out of the total 200 children, 42(21%) had <1year of age, 80(40%) has 1-5 year age, 62(31%) has 5-15 year and 16(8%) had reached the skeletal maturity. Majority, 130(65%) were boy and 70(35%) were girls. None of the participant was married till study completion. When education status was asked, majority 127(63.5%) were illiterate and 28(14%) children were admitted in nursery, 27(13.5%) had primary education, 13(6.5%) completed the matriculation and only 5(2.5%) children were enrolled as undergraduate. Conclusion: Low socioeconomic status and illiterate population were in majority. Most children had age up to five years with one third of the children had associated illness. Keywords: Cerebral palsy, congenital disease, central nervous system, motor impairment syndrome, gait analysis.
Contraceptive counseling: An unaddressed issue of Post Renal transplant women of reproductive age
Authors: Sultan Khawar , Maqsood Zainab , Abbasi M. Sajid Rafiq , Hussain Shoukat , Abbasi M. Arshad , Baloch Muhammad Hussain
Published: September 2022

Background: Counseling regarding conceiving and contraception in post renal transplant female recipients is neglected and important aspect of post-transplant care. Aim: To conduct to report use of contraceptive measures, pregnancy and its outcomes during post-transplant period. This study highlights the importance of contraceptive counseling after renal transplant. Results: Out of total 14 patients of our study only 5 (36%) were using contraception while 9 (64%) were not using any contraceptive method. Out of 9 non users 7 patients were never counseled regarding contraception. Moreover they had no awareness regarding drug modification or renal and feto-maternal outcomes of pregnancy after renal transplant. Conclusion: Reproductive age female patients undergoing renal transplant should be given special attention regarding counselling on contraception, pregnancy and it outcomes. Key words: Contraception, renal transplant, pregnancy,
FAKTOR RISIKO YANG MEMENGARUHI GANGGUAN JIWA
Authors: Kirana Wahyu , Anggreini Yunita Dwi , Litaqia Wulida
Published: September 2022

Pendahuluan: Masalah kesehatan jiwa merupakan salah satu masalah kesehatan yang serius dan terbesar selain beberapa penyakit generatif karena jumlahnya yang terus mengalami peningkatan dan membutuhkan proses penyembuhan yang panjang seperti penyakit kronis. Penelitian ini bertujuan untuk mengetahui faktor risiko yang memengaruhi gangguan jiwa. Metode: Penelitian ini merupakan penelitian dengan rancangan deskriptif analitik dengan metode case control. Sampel penelitian sebanyak 36 orang yang terdiri dari 18 ODGJ pada kelompok case dan 18 orang bukan gangguan jiwa yang berobat ke UPT Puskesmas Tanjung Hulu yang dipilih secara purposive sampling. Instrumen penelitian yang digunakan terdiri dari kuesioner data demografi dan kuesioner faktor risiko gangguan jiwa, data selanjutnya dianalisis secara univariat dan bivariat dengan uji chi-square. Hasil: Hasil penelitian didapatkan bahwa faktor risiko yang berhubungan dengan kejadian gangguan jiwa adalah faktor genetik (p=0,036, OR=10,818),trauma masa kecil (p=0,022, OR=5,500), stres (p=0,041, OR=5,000) dan pola asuh (p=0,022, OR=0,182), sedangkan faktor risiko yang tidak berhubungan dengan kejadian gangguan jiwa adalah cacat kongenital (p=0,729, OR=1,273), cedera (p=0,427, OR=0,520), jasmaniah (p=0,554, OR=0,471), penyalahgunaan obat (p=0,701, OR=1,346), penyakit kronis (p=0,554, OR=2,125), hubungan keluarga (p=0,735, OR=0,739), struktur keluarga (p=0,311, OR=0,284), sistem nilai (p=0,503, OR=0,636), kepincangan antara keinginan dan kenyataan (p=0,701, OR=0,743), sosial ekonomi (p=0,632, OR=1,600) dan perpindahan keluarga (p=0,675, OR=1,429) tidak bermakna sebagai faktor risiko gangguan jiwa. Kesimpulan: Faktor risiko gangguan jiwa terdiri dari faktor biologis, psikologis dan sosiokultural. Beberapa faktor risiko yang mempengaruhi gangguan jiwa dapat dimodifikasi untuk meminimalkan terjadinya gangguan jiwa.
The reasons for the arrival of the hadith and its impact on the understanding of the hadith
Authors: Iqbal Dr. Farzana , Gul Hafiza Maah , Noor Hafiza Mah
Published: September 2022

It is imposible to understand The Ahkam-e-Deen without knowing the Ahadees of Prophet (ﷺ). In order to get  the correct Knowledge of the hadees (Hadith ), It is necessory  to know the”Asbab-e- warood-e-Hadith” That is why  the narrators gave it the status of  ilm (knowledge), an they  has been made it obligatory for undertanding the Hadith as it is imposibe to understand The Quran without knowing the “Shan-e-nazool” so it is not possible to get the correct knowledge of the Hadith without knowing the Asbab-e-warood-e-Hadith. In this article the importance of ilm-e- Asbab-e-wrood-e-Hadith has been discused for the understanding of  Hadith and the types of this ilm,Its importnace, Its relation to the Shan-e-Nazool and the beniftsof this  have been explained. In preparing this article, authenticand basic  sources have been  used  directly so  that the research work can be accepted and students can  benefit from it.
Periodontal pocket treatment with diode laser 940 nm
Authors: Aboud Sally S. , Taha Hanan J. , Mardan Balsam
Published: September 2022

Introduction: Many adjunctive treatment have been introduced to enhance the therapeutic outcome of periodontal treatment. Diode laser 940 nm has the potential to act as antibacterial and enhances wound healing. Material and methods: 114 periodontal pockets of 5 chronic periodontitis patients having 3 mm≤IPD≤8 mm, who had been treated in the private clinic, Baghdad, Iraq were subjected to the current study. The treatment was done by using 940 nm wavelength diode lasers for three months with twice weekly recall. Results: There was a highly significant improvement in the pocket depth at the end of the 12th week in which the depth of patient’s pockets was reduced to half their depth at the initial visit that run in parrelel with a significant increase in the lenghths of the alveolar bone that measured by OPG after six weeks of treatment which persist to increase significantly till the 12th week of treatment which is accompanied by  bone biostimulation that improved after the exposure to the diode laser. Conclusion: diode laser 940nm can be considered as a promising periodontitis treatment as it causes a rapid reduction in probing depth with an increase in the bone bio-stimulation when it used in an appropriate protocol.
Morphological studies on some Orobanche L. species in Egypt
Authors: El-Taher Ahmed M. , Mohamed Fatema S.
Published: September 2022

Broomrapes are root holoparasites in the family Orobanchaceae. These parasites can cause substantial losses, 5%–95%, in important crops . These plants parasitize legumes, oilseeds, nightshades, and crucifers in warmer areas of Europe, Africa, the Americas, and Asia. A full taxonomic study for seven taxa of Orobanche in Egypt; O. ramose L. var. ramose, O. mutelii F. W., O. lavandulacea Rchb., O. aegyptiaca Pers., O. crenata Forssk., O. cernua Loefl., and O. minor Sm. var. minor is presented in this article. The work includes a key to taxa, taxa descriptions, LM and scanning electron microscopy (SEM) images of pollen, seed, and seed‐coat morphology, and a numerical analysis of results. Macromorphological characteristics are key features for differentiation among taxa. Diagnostic characteristics include simple and branched stems, presence and absence of bracteoles, constriction of corolla tubes, and color and length of corollas. SEM of pollen identified three types: prolate-spherical, oblate-spherical, and spherical. Three apertures were also recorded; inaperturate- tricolpate, tricolpate, and inaperturate. Ornamentation included only microreticulate and scabrate-verrucate. LM investigation of seeds recognized three shapes: ellipsoid to ovoid, ovoid to ellipsoid, and ovoid. SEM identified four morphological groups.
Risk factors for mortality in children with cyanotic congenital heart disease associated with brain abscess
Authors: Pratiwi Fauziah , Gunawan Prastiya Indra , Rahman Mahrus A. , Noviandi Riza , Samosir Sunny Mariana
Published: September 2022

Brain abscess is a local infection within the brain parenchyma. Predisposing factors include cyanotic congenital heart disease (CHD). Identification of risk factors for mortality is important to determine the prognosis. A case-control study of children with cyanotic CHD associated with brain abscess was conducted in the pediatric ward of a hospital from January 2016 to December 2020. Data were collected from medical records with the case to controls ratio of 1:3.07. A total of 61 children were evaluated, 46 children survived and 15 children non-survived. From 11 risk factors evaluated, 6 risk factors had a significant different of mortality risk included the level of hemoglobin (p=0.07), leukocyte (p=0.063), Neutrophil-to-lymphocyte ratio (NLR) (p<0.001), peripheral oxygen saturation (SpO2) (p=0.00), multiple abscesses (p=0.008), brain abscess diameter (p<0.001). Multivariate logistic regression analyses revealed significant risk factors for mortality in cyanotic CHD children with brain abscesses were NLR (OR 13.62, 95%CI 2.123-87.319, p=0.006); SpO2 (OR 1.5, 95% CI 1.25-2, p=0.04); brain abscess diameter (OR 7.61, 95%CI 1.064-54.434, p=0.043). NLR, brain abscess diameter, and SpO2 were the risk factors in increasing mortality in cyanotic CHD children with brain abscess. The prevention of abscess cerebral development and cyanotic CHD management are needed to reduce the mortality.
Determine the optimal conditions for the growth of kytococcuc sedentarius bacteria when analyzing plastic waste and identify some of the decomposition products
Authors: Al-Rawi Al-Rawi , Fakhri Dhafer , Ibrahim Rawnaq Aadil
Published: September 2022

This study aimed to determine the optimal conditions for the growth of Kytococcuc sedentarius bacteria isolated  from landfill soil in Anbar province using nylon bags as the only source of carbon and energy, used in liquid nylon bag medium in experiments to determine optimal conditions for growth, the best pH at 7 PH, the best temperature at 30 °C, the best vaccine volume was at 2 ml  / 100 ml, and the best incubation period was after  4  One week, applying all these optimal growth conditions for bacterial isolation, the decomposition rate of nylon bags used in the study was 43.2%.
Comparison of biochemical/haematological parameters in healthy vs preeclamptic females
Authors: Samad Saqib , Gul Afshan , Mehmood Asma , Fida Najma , Khalid Maham , Farhat Sahar
Published: September 2022

Objectives: To evaluate and compare the Biochemical/Haematological parameters in healthy (pregnant subjects) vs preeclamptic females. Methodology: This descriptive cross-sectional study was planned/conducted at IBMS KMU Peshawar and the data was collected from the Dept. of Gynaecology & Obstetrics-Lady Reading Hospital Peshawar, from June 2019 to July 2020. One hundred thirty-eight pregnant subjects between the gestational ages of 26-30 weeks were included in the study. The subjects were divided into two cohorts; Patients with preeclampsia (Group I N=92) and a Normotensive Control Group; women with normal pregnancy (Control group N=46). Blood from the subjects was checked for Haemoglobin (Hb) and Platelet (PLT) levels and Body Mass Index (BMI) among other parameters. Blood was taken and analysed at the Hospital Lab via Cobas 6000 analyser. Data was analysed using SPSS version 26.0 for MacBook Pro. Results: Body mass index of PE group was significantly higher compared to normal group (p<0.001). Similarly, mean platelet counts and hemoglobin in PE group was lower as compared to normo-tensive group and the differences were statistically significant (p<0.05). There was no significant difference in mean gestational age (weeks) between the two groups (27.83 ± 0.95 vs 27.78 ± 1.07, p= 0.33) was observed.
Effect of Thermization and storage period on the quality parameters of yoghurt
Authors: Grace Oluwatoyin Ogunlakin  , Rukayat Abiola Suara  , Tajudeen Abidemi Sunmola
Published: September 2022

This research work was to investigate the effect of thermization and storage period on the quality parameters of yoghurt. The proximate, physiochemical and sensory evaluation of yoghurt thermized at 50 – 70 °C and stored at 0 – 4 weeks were studied. The moisture contents ranged from 86.15 to 89.94%, ash content ranged from 0.25 to 0.89%, fat content ranged from 2.98 to 3.91%, protein content ranged from 3.21 to 5.08%, carbohydrate content ranged from 3.25 to 5.07% and total solid ranged from 10.07 to 13.85%. There was decrease in the pH and total titratable acidity of the sample as days passes by, the value increase from 3.90 to 6.90 (pH tends towards alkaline) and 0.53 to 0.83% (total titratable acidity). Also, it was observed that yoghurt sample thermized at 65 °C had the most sensory properties (taste, odour, texture, appearance and overall acceptability) acceptability. The findings reveals that the higher the thermization temperature, the lower the degree of deterioration and also, that storage reduces the quality parameters/attributes of the yoghurt hence makes the yoghurt unfit for consumption.
Destituinte
Authors: Freitas Lorena Martoni de
Published: September 2022

Este trabalho busca explorar a formação do conceito de “destituinte” no interior da prática política e da crítica filosófica. Para tanto, identifica seu surgimento no interior da crise do conceito de poder constituinte instaurada nos estudos constitucionais, no qual é tratado como uma mera questão de princípio da ordem jurídica que, sob uma perspectiva teleológica da história, é absorvido pelo poder constituído uma vez consolidadas as estruturas ditas democráticas do atual Estado de Direito. Nessa esteira, com o suposto intuito de garantir a perenidade dos direitos fundamentais e a estabilidade das instituições democráticas – em especial, após as experiências totalitárias que marcaram o século passado –, a inerente dimensão des-constituinte do poder constituinte vem sendo paulatinamente silenciada. Porém, trata-se de tendência teórica que tem enfrentado sérios desafios face aos novos movimentos sociais que vêm tomando as ruas em vários locais do globo nas últimas décadas, sendo justamente nesse contexto que uma nova abordagem passou a se configurar, voltada a analisar de forma mais aprofundada essa dimensão desconstituinte, e que podemos reunir sob o rótulo de “pensamento do destituinte”.
Engrenagens psi-jurídicas na conformação do inimigo patologizado
Authors: Pescarmona Danilo
Published: September 2022

O presente artigo se propõe a discutir a região conhecida como Cracolândia enquanto um laboratório de experimentações da ação política no contemporâneo. Adotamos essa definição na medida em que nesse território é testada uma série de práticas voltadas à militarização da vida e que será experimentada em outras territorialidades sob a forma de repressão e controle de corpos, bem como ao aprimoramento das práticas de exceção. Paralelamente, utilizaremos a genealogia foucaultiana para demonstrar como o conceito de anormal, entendido como o inimigo patologizado, é preenchido pelo usuário de crack – uma subjetividade reduzida à sua condição patológica de dependente químico que perdeu sua racionalidade em função do uso compulsivo da substância –, e sobre o qual incidirá às medidas autoritárias em função do risco que representa. Com essa discussão, pretendemos demonstrar que elementos de exceção convivem no interior da democracia e fundam as características da violência na sociabilidade brasileira.
A força dos afetos no direito e na multidão
Authors: Sousa Bizerril Vitor
Published: September 2022

A teoria do poder constituinte formulada por Antonio Negri diferencia-se das demais concepções existentes, visto que, em vez de buscar arrefecê-lo ou controlá-lo, Negri apresenta-o como um procedimento absoluto, ilimitado e inconcluso. Não obstante seu caráter vanguardista, a robusta fundamentação teórica e a complexa pesquisa efetuada por Negri na elaboração de seu conceito de poder constituinte apresentam, conquanto de forma sintética, algumas possíveis críticas ao seu construto teórico a partir da filosofia de Baruch de Espinosa. Considerando haver Negri utilizado a filosofia espinosiana como argumento basilar de sua proposta teórica, inclusive adotando e interpretando conceitos próprios daquela, analisam-se temas como dinâmica e ciência dos afetos, multidão e direito, que, por serem caros à literatura de Espinosa, merecem, de forma crítica e percuciente, serem examinados e cotejados com elementos da teoria do poder constituinte negriana.
Perspectivas para a desinstituição da democracia representativa
Authors: Ribeiro Rodrigo
Published: September 2022

O presente artigo propõe uma análise radicalmente crítica da democracia representativa, inserindo-se nas discussões que posicionam a democracia radical como chave de leitura crítica dos mecanismos representativos. Nesse sentido, utiliza-se o conceito de desinstitiução, tal como proposto por Andityas Matos, como uma prática que permita a ruptura com a representação política e a emergência de novas configurações políticas. Dialogando com autores como Jacques Rancière e Ellen Woods, esse trabalho busca evidenciar os problemas da fórmula nomeada democracia representativa, tensionando as condições do presente que impõem a prática representativa como destino inescapável das sociedades contemporâneas. Traçando paralelos com autores como Douglas Lummis, Cornelius Castoriadis e o grupo Comitê Invisível, objetiva-se apresentar a democracia radical como realidade possível, apresentando, para tanto, os elementos que fundamentam a aposta na recomposição dos sentidos políticos de uma comunidade efetivamente democrática.
A invenção da nordestina
Authors: Moura Samantha Nagle Cunha de
Published: September 2022

Resenha da peça teatral A invenção do Nordeste da companhia de teatro Grupo Carmin
Comparación de la eficiencia de transformación entre diferentes cepas de E. coli
Authors: Gómez Fierro María Georgina , García Cárdenas Samantha Yolotzin , Ruvalcaba Hidrogo Daniela Grissel , Alvarado González Carmen Carolina , Juárez Acosta Óscar Enrique , Espinoza Duarte Mayela Rosario , Espino Solís Gerardo Pável
Published: September 2022

La transformación es la introducción y expresión de ADN exógeno por células bacterianas. La eficiencia de la transformación puede medirse en unidades formadoras de colonia/ml (UFC/ml) y es susceptible al método utilizado, a la cepa bacteriana utilizada para la expresión y al propio vector. En este trabajo se busca evaluar las diferencias en la eficiencia de transformación de dos plasmidos de expresión (pExp-Lib y pSF-CMV- Ub-puro-SV40 Ori Sbfl), en cuatro cepas diferentes de E. coli (DH5a, BL21, XL1-Blue y TG1) utilizando un método de preparación de células competentes basado en el uso de MgCl2/CaCl2. En todas las cepas utilizadas, el crecimiento bacteriano y la eficiencia de transformación fueron mayores para las cepas con el vector pExp, a excepción de BL21, donde la eficiencia fue más elevada para el vector pSF.

DOI: https://doi.org/10.54167/tch.v13i2.434
Idiopathic Toe Walking: An Update on Natural History, Diagnosis, and Treatment
Authors: Bauer Jeremy P. , Sienko Susan , Davids Jon R.
Published: September 2022

Toe walking is a common presenting report to an orthopaedic practice. Evaluation of a child with toe walking includes a thorough history and physical examination to elucidate the diagnosis. When no other diagnosis is suspected, a diagnosis of idiopathic toe walking is often given. Despite the high prevalence of the condition, there is notable controversy of the nomenclature of the disease. Recent research has shed more light on both the natural history and the genetic basis. The use of motion analysis, including EMG and multisegment foot model, may help both differentiate children with mild forms of cerebral palsy and evaluate outcomes after treatment. Early treatment for young children with adequate range of motion (ROM) is generally reassurance because most young children with idiopathic toe walking are expected to resolve spontaneously. When the toe walking persists, treatment options include both surgical and nonsurgical management. Nonsurgical management centers on obtaining ROM through stretching and serial casting, followed by gait retraining and bracing treatment. Surgical lengthening at either the Achilles or gastrocnemius level improves the ROM of the ankle and then similarly requires therapy and bracing treatment to obtain a more normalized gait.