bluuebunny/crossref_metadata_2025 huggingface dataset:
Early and Late Complications of Ahmed Glaucoma Valve Implant in a Real-World Situation
Authors: Farooq Saima , Mahsood Yousaf Jamal
Published: December 2023

Purpose:  To determine the early and late complications of Ahmed Glaucoma Valve (AGV) implant surgery.
Study Design:  Interventional case series.
Place and Duration of Study:  Ophthalmology department of MTI-Hayatabad Medical Complex Peshawar, from May 2018 to February 2023.
Methods:  All the patients between May 2018 and February 2023 who underwent AGV implant were included in the study. Data included patient's age, gender, indications for surgery, type of AGV implant used, length of follow-up period, intraocular pressure (IOP), number of topical glaucoma medications used, early and late complications, and the final outcome. Continuous variables (duration of follow-up, best corrected visual acuity, IOP, and number of topical anti-glaucoma medications) were represented in means and standard deviations. Paired t-test was applied for comparison of means between baseline and last follow-up data. A p-value of < 0.05 was considered statistically significant.
Results:  A total of 28 eyes were included. Mean age of the patients were 28.75 ± 20.5 years. Duration of follow-up was 213.96 ± 169.33 days. There were 53.85% females. Commonest indication was congenital glaucoma 7 (25%). Majority, (n = 18, 64.3%) of the eyes had previous cataract surgeries followed by glaucoma, 13 (46.4%). The commonest early post-operative complication was hyphema (25%) and commonest late complication was hypertensive episode 32.1%. Majority of the eyes 23 (82.1%) did not require any further intervention for these complications.
Conclusion:  Majority of AGV complications are self-limiting, necessitating just conservative therapy. However, serious complications might happen that could lead to blindness, therefore the surgeons should have strategies for treating or preventing them.
Association of Head Circumference, Gestational Age and Birth Weight with Severity of Retinopathy of Prematurity
Authors: Saad Jan  , Muhammad Ali Tahir  , Arifa Farooq Ghazipura  , Azizur Rehman Arain  , Alyscia Cheema
Published: December 2023

Purpose:  To determine relationship between head circumference, gestational age and birth weight with stage of Retinopathy of Prematurity (ROP).
Study Design:  Descriptive observational.
Place and Duration of Study:  Jinnah Postgraduate Medical Centre (JPMC), Karachi from January 2022 to June 2022.
Methods:  Infants born at or before 32 weeks of gestation, birth weight of less than or equal to 1500 grams at birth were enrolled. Their head circumference, gestational age and birth weight was measured and Fundoscopy was done to find out ROP. Staging of ROP was recorded four weeks after birth. The severity of ROP was correlated with head circumference, gestational age and birth weight.
Results:  Of the 82 infants with ROP, 44 (54%) were male and 38 (46%) were female. Mean gestational age was 30 ± 1.4 weeks (range 27-32 weeks),mean birth weight was 1275 ± 155 gram (range 800-1500), and mean  Fronto Occipital Circumference (FOC) was 29 ± 1.6 cm (range 25-32 cm). Degree (stage) of ROP was as follows; 14 (17.1%) infants had stage 1 disease, 24 (29.3%) had stage 2 disease, 28 (34.1%) had stage 3 disease, 13 (15.9%) had stage 4 disease and 3 (3.7%) had stage 5 disease. There was statistically significant association of gestational age, birth weight and head circumference (FOC) with the degree of ROP (P<0.001)
Conclusion:  Head circumference, gestational age and birth weight had a significant association with degree of ROP (P<0.001).
Comparison of Biometric Formulae for Intra Ocular Lens Power Calculation
Authors: Ghaffar Mariam , Muneer Quraishy Muhammad , Adnan Shaikh Muhammad , Hussain Mehvash , Sultan Zaheer
Published: December 2023

Purpose:  To determine the accuracy of different biometric formulae for intraocular lens power (IOL) calculation in predicting a target postoperative refraction within ± 1.0 diopters in patients with long axial length undergoing phacoemulsification.
Study Design:  Cross sectional study.
Place and Duration of Study:  Department of Ophthalmology and visual sciences, Unit 1 Dow University of Health Sciences, Dr. Ruth KM Phau Civil Hospital Karachi from February 2019 to August 2019.
Methods:  The study included 45 eyes with cataract and preoperative uncorrected visual acuity ranging from 6/60-6/12, axial length of 24.5 to 27.0 mm with no other ocular problem. IOL power was calculated with SRK-T, Holladay 1 and Haigis formula installed in optical biometer AL-Scan (Nidek Co, Ltd., Gamagori, Japan) and by Barrett universal 2 formula from http://www.apacrs.org/barrett_universal2/. Patients underwent phacoemulsification by single surgeon. Follow up included refractive status using Autorefractokertometer, URK-700 (Unicos Co., Ltd., Korea) at 6th week post-operatively. Deviation of actual postoperative refraction from the predicted target preoperative refraction were calculated and values within ± 1.0 diopter were considered accurate. Data was analyzed using SPSS version 22.
Results:  Outcome in terms of postoperative refractive error (+1D to -1D) with respect to biometric formula showed 100% accuracy using Haigis formula, 90% accuracy using SRK-T formula, 72.72% accuracy using Barrett universal II formula and 66.67% accuracy using Holladay-1 formula.
Conclusion:  Haigis formula proved to be more reliable and accurate than SRK-T, Holladay 1 and Barrett universal II formulae for calculation of intraocular lens power in eyes with long axial length.
Comparison of Sedation Quality and Pain with Propofol-Thiopental Sodium Versus Propofol-Etomidate in Cataract Surgery
Authors: Nazemroaya Behzad , Shetabi Hamidreza , Moradi Farsani Darush , Ariya Ali
Published: December 2023

Purpose:  To compare the effectiveness of Propofol + Sodium thiopental (Thiofol) versus Propofol + Etomidate (Etofol) in achieving a more favorable sedation during phacoemulsification.
Study Design:  Randomized controlled trial.Methods:  A total of 64 patients (25 females and 39 males) were assessed with an average age of 65.14 ± 13.34 years. Patients who underwent elective phacoemulsification operation under sedation and were randomly divided into the Propofol + Sodium thiopental (Thiofol) and Propofol + Etomidate (Etofol) groups. There were 32 patients in each group. Demographic information, sedation level, medical condition, anesthetic complications, hemodynamic parameters prior to, during, and following the operation, and the visual analog scale (VAS) were measured by an anesthesiologist and compared.
Results:  The groups showed significant differences in the levels of Ramsay scores (P<0.001). The frequency of Ramsay scores 2 and 3 was 43.75%, 56.25%, and 0%, 100% in Etofol, and Thiofol groups, respectively. The average recovery time showed a significant increase in the Etofol group compared to the Thiofol group (P<0.001); the VAS in the Thiofol group showed a significant rise compared to the Etofol group (P <0.001).
Conclusions:  Although the sedation quality while phacoemulsification cataract surgery was acceptable with both drugs and the results between groups were not significantly different considering recovery time and pain control, recovery time was less in Etofol and pain control was more effective in Thiofol.
Rare Orbital Myiasis in Post Exenteration Socket: A Case of Orbito Maxillary Mucormycosis
Authors: Kakkar Arushi , Bala Madhu
Published: December 2023

We report a case of orbital Myiasis in post-exenteration socket in a 60-year-old diabetic female who was diagnosed with right orbito-maxillary mucormycosis and underwent exenteration and supra structure maxillectomy, seven years back. Turpentine oil packing and hydrogen peroxide wash was given followed by removal of the maggots with a blunt forceps. The collected maggots were stored in 10% formalin followed by maggot identification. Maggots were of blowfly species, Chrysomyabezziana. These maggots have a unique tendency to invade healthy tissues extensively besides necrotic tissues. This is probably a rare instance where orbital myiasis had occurred over the granulation tissue covering posterior orbital bones extending to the floor of the maxillary antrum. She was primarily treated with broad spectrum antibiotics, anti-parasitic agents followed by manual removal of the maggots subsequent to which the wound began to heal by secondary intention.
Prediction of COVID-19 course in patients with stage 3 chronic kidney disease and type 2 diabetes mellitus
Authors: Klochkova N. N. , Lysenko M. A. , Zeltyn-Abramov E. M. , Markova T. N. , Poteshkina N. G. , Belavina N. I. , Kondrashkina S. V.
Published: December 2023

BACKGROUND.Patients with Diabetes Mellitus 2 (DM2) and Chronic Kidney Disease (CKD) are at a high risk for severe clinical course of COVID-19. The high mortality rate due to COVID-19 and widespread distribution of DM2 and CKD all over the world make it necessary to determine the predictors of adverse outcome of novel coronavirus infection (NCI).

AIM.The identification of predictors of NCI adverse outcome in patients with DM2 and CKD stage 3 due to diabetic kidney disease.

Patients and Methods. The patients with NCI and CKD stage 3 were included in observational retrospective uncontrolled study during the follow-up period from 04.01. to 10.30.2020. The study endpoints were the outcome of NCI (survivors/nonsurvivors). Data were collected from electronic versions of case records. Demographic, DM2-related, CKD-related and NCI-related baseline parameters/signs were studied as independent variables.

RESULTS.90 patients with DM2 and CKD stages 3 (Me GFR 43[37; 49] ml/ min/1,73m2) were included, mean age 70 [69; 78] y, females – 56 %, the mortality rate – 21 %. The independent predictors of NCI adverse outcome were detected using a single factor analysis (odds ratio). Among them are: initial prandial glycemia ≥ 10 mmol/l (ОR 11,8; 95 % CI 3,13–44,9; р <0,001), albuminemia at admission ≤ 35 g/l (ОR 5,52; 95 % CI 1,85–16,55; р = 0,012), initial proteinuria ≥ 1 g/л (ОR 6,69; 95 % CI 1,95–23,00; р = 0,002), News2 ≥ 5 at admission (ОR 14,7; 95 % CI 3,15–48,8; р <0,001), lung damage CT 3–4 at admission (ОR 31,7; 95 % CI 6,59–52,85; р = 0,04). A prognostic model was constructed to determine the risk of lethal outcome using logistic regression method. The detected risk factors were used as variables. The predictive value of the model was 93 % according to ROC-analyses data.

CONCLUSION. The detected predictors of adverse outcome are the part of routine screening available in pre-hospital setting and at hospital admission. Early identification of predictors allows optimizing patient routing and selecting the best treatment strategy for each patient.
Manifestações dermatológicas em pacientes pediátricos associadas à infecção da COVID-19- Revisão integrativa da literatura
Authors: Carianne Rodrigues Gomes Loren , Yukari Kamiyama Samira , Cezar Oliveira Junior Julio , Pereira Morais Isabella , De Negreiros Feitosa Maria Carolina , Junio Vieira Araújo Ricardo , De Souza Duarte Felipe
Published: December 2023

A infecção por COVID-19 acarreta diversas modificações no organismo humano, incluindo sinais e sintomas que podem variar em cada indivíduo, principalmente quando se trata de pacientes pediátricos. Os achados clínicos documentados nessa população têm formas de apresentação distintas, o que faz com que ainda se saiba pouco relacionado a essa questão. O objetivo do presente trabalho foi realizar uma revisão integrativa da literatura indexada publicada nos últimos anos a respeito das manifestações dermatológicas em pacientes pediátricos associada à infecção pela COVID-19. Para tal, foi realizada uma busca na base de dados do PubMed, com os termos “Dermatologic manifestations”, “Pediatrics” e “COVID-19”, unidos pelo operador boleano “and”. Foram encontrados 59 artigos e após a aplicação dos critérios de inclusão e exclusão, restaram 10 artigos que foram incluídos nesse trabalho. Como resultado, notou-se que a manifestação cutânea mais associada às crianças foi a lesão que se assemelha à frieira, de característica eritematosa ou violácea que pode ser acompanhada por sensação de coceira e dor nos dedos dos pés, também denominado de covid toes. Ademais, outros estudos evidenciaram rashes eritematosos em terminação de membros e tronco como sinais mais prevalentes, podendo esses, ainda estarem associados à síndrome inflamatória multissistêmica e à doença de Kawasaki. Conclui-se que as manifestações cutâneas da infecção pelo COVID-19 ainda são variadas e pouco conhecidas. É preciso haver um estudo de maior profundidade em centros médicos, hospitais e comunidades para delinear de forma concreta quais as principais manifestações, suas características e seus respectivos tratamentos.
Hyperparameter optimization in machine learning models: a comparative study
Authors:   Denisenko V.V. Maslov A.A. CHesnikov L.S. Klimenko K.S
Published: December 2023

A comparative study of hyperparametric optimization methods in machine learning models is carried out. The evaluation of the various optimization methods performance on such types of models as support vector machines, decision trees and neural networks is given. The influence of hyperparameters on the model performance is evaluated and the effectiveness of various optimization methods is compared. The results obtained give an idea of the hyperparametric optimization methods effectiveness and can be used to select the best method. The work results may arouse interest in researchers in the field of machine learning who seek to improve the performance of their models by optimizing hyperparameters.

Keywords
hyperparameter optimization, machine learning, comparative study, support vector machines, decision trees, neural networks, grid search, random search, Bayesian optimization, model performance, optimization methods
OUTLOOK ON ENERGY AND EMPLOYMENT SCENARIOS IN SELECT SOUTH ASIAN NATIONS: SEVEN-YEAR FORECAST (2023-2030)
Authors: Niranjana S  , Annie Thomas
Published: December 2023

Coal is the primary energy source of countries India, Pakistan, and Sri Lanka. Coal is a fossil fuel and thus is non-renewable. In this study, we are analyzing and forecasting various energy parameters, encompassing total energy generation, consumption, the proportion of renewables in the overall primary energy mix, and socio-economic parameters such as population statistics, unemployment rates, and the percentage of women in the workforce. The objective is to leverage this data to evaluate forthcoming business and employment prospects within the renewable sector, and how it can reduce unemployment rates and improve womens participation in the workforce. Additionally, the existing job opportunities in the renewable energy market are also assessed. The high gap between energy consumption and generation indicates the need for the establishment of renewable energy infrastructure.
KEYWORDS: Renewable Energy, Fossil Fuels, Unemployment rate, Energy consumption
El condicionamiento operante de Skinner, la disonancia cognoscitiva de Festinger y la psicología evolucionista como herramientas conceptuales para la comprensión de las conductas protectivas ante la pandemia del covid-19
Authors: García José E.
Published: December 2023

La pandemia del Coronavirus, Covid-19 o SARS-CoV-2, que se inició en diciembre del 2019 y continúa en desarrollo, constituye uno de los retos más grandes a la salubridad pública que haya enfrentado la humanidad. Los efectos negativos para el cuidado de la salud y la vida de las personas, la economía, el comercio, la educación, el turismo, y para varias otras áreas de la actividad humana, son considerables. Los psicólogos no permanecieron ajenos a la situación y elaboraron varios análisis e investigaciones que exploran sistemáticamente los efectos generados por la prevalencia del virus. Uno de los problemas que se observaron con mayor frecuencia, y que fueron responsables de la expansión acelerada de la enfermedad, es la reticencia mostrada por muchas personas a incorporar de manera cotidiana y sistemática las reglas de prevención como el uso de barbijos o protectores faciales, lavado constante de manos y el distanciamiento físico. Dentro de esta línea, el presente artículo ofrece un análisis basado en tres perspectivas de la psicología que podrían clarificar la comprensión del fenómeno: el condicionamiento operante de Skinner, la teoría de la disonancia cognoscitiva de Festinger y la psicología evolucionista. El enfoque es de carácter teórico y se inicia con una consideración de las fuentes primarias y secundarias relevantes al problema. Se ofrecen algunas sugerencias y recomendaciones que pueden ser de utilidad para la prosecución de un análisis sistemático de las variables psicológicas relacionadas al Covid-19.
Pengaruh Usia terhadap Tingkat Tekanan Darah, serta Potensi Gangguan Kardiovaskular
Authors: Ina Ferawati Bangkit , Setiana Mira
Published: December 2023

Cardiovascular disorders remain a major cause of global morbidity and mortality. The main aim of this study was to identify patterns of association between age and blood pressure and analyze their potential implications for the risk of cardiovascular disorders. The focus of blood pressure analysis is on systolic blood pressure (TDS). The research method involved collecting data on age, blood pressure, and disease history from 42 respondents in Hamlet VI Sonosewu, Kasihan, Bantul. All statistical analyses were performed using Ms. Excel. Statistical analysis is used to describe the pattern of relationships between these variables. The results of the correlation test showed that there is a relationship between age and blood pressure in the sample or population analyzed, which is confirmed by the ANOVA test (p-value: 0.002) and t-analysis test (p-value: 0.002), which produces a p-value < alpha or significance value (0.050). The potential for cardiovascular disorders is known from the results of the chi-square test, the Pearson chi-square statistical value (0,732)< the critical chi-square value (3,840). Based on these results, it can be concluded that in the context of this study. However, age cannot be the main factor determining blood pressure levels and is used as the only risk factor for cardiovascular disorders. Factors such as disease history and lifestyle can be considered as other factors that influence blood pressure levels and the risk of cardiovascular disorders. Blood pressure monitoring and appropriate preventive measures are essential, especially in the elderly age group
Efektifitas Video Edukasi Pembuatan Mpasi 4 Bintang Terhadap Pengetahuan, Sikap Dan Keterampilan Orang Tua Dalam Pencegahan Stunting Pada Balita
Authors: Utami Ressa Andriyani , Ernawati  , Saragih Dameria Br
Published: December 2023

Stunting is a national problem related to chronic malnutrition which occurs due to multifactors including nutritionalintake, nutritional parenting, genetics, infectious diseases and hygiene. Currently, breakthrough interventions andreal action are needed to overcome editing problems. This research aims to determine the effectiveness of theeducational video for making the MPASI 4 Star menu on the knowledge, attitudes and skills of parents in preventingstunting in toddlers. The research design used is quantitative, quasi-experimental research using a one group pretestposttest design approach. This research was conducted on parents of toddlers in DKI Jakarta with a sample size of 44respondents. The results showed that there was a significant difference in knowledge before and after the intervention(p value 0.000), there was a significant difference in attitudes before and after the intervention (p value 0.000), therewas a significant difference in skills before and after the intervention (p value 0.000 ). It is hoped that this researchcan be an alternative action in the form of education via video for parents to overcome stunting in toddlers and todevelop care, further research can be carried out regarding interventions to deal with stunting.
Hubungan Cyberloafing Behavior Dengan Organizational Commitment Pada Pegawai Di Puskesmas
Authors: NURSYA FEBRIYANTI , Nurul Prihastita Rizyana
Published: December 2023

Health centers are one of the important service aspects for the community. All employees who work at the health center must always be ready to provide the best service starting from doctors, nurses, administrative staff, pharmacists, and cleaning services. Cyberloafing behavior is categorized as disciplinary behavior, the division of employee concentration between work and cyberloafing behavior has an impact on piling up work, low work productivity, poor work quality, can interfere with the smooth work process and slow public services so that it will have a negative impact on the image of the organization. In the process, good organizational commitment is needed so that a puskesmas goal of serving patients maximally can be achieved by reducing deviant behaviors that exist in organizations such as cyberloafing behavior. This research is a quantitative study using a cross sectional study design. With the dependent variable being organizational commitment while the independent variable is cyberloafing behavior. The research was conducted in June 2023 at one of the health centers in Padang City. The population and sample of this study were all employees totaling 49 people using a questionnaire instrument. Data were analyzed univariately by looking at the frequency distribution table and bivariate analysis using the ChiSquare test.Based on the results of the research conducted, almost half of the respondents did cyberloafing behavior and more than half of the respondents had employee commitment. The statistical test results obtained p = 0.023, meaning that there is a significant relationship between cyberloafing behavior and organizational commitment It is recommended that the Puskesmas begin to socialize the impact of cyberloafing behavior in daily employee work activities.
Hubungan Manajemen Diri Dengan Kadar Gula Darah Puasa Pada Penderita Diabetes Melitus Tipe 2 Di Puskesmas Andalas Kota Padang
Authors: Desnita Ria , Andika Mira , Alisa Fitria , Efendi Zulham , Amelia Weny , Despitasari Lola , Oka Surya Defrima , Syofia Sapardi Vivi
Published: December 2023

Diabetes Mellitus (DM) type 2 is a metabolic disorder characterized by hyperglycemia or high blood sugar levels and impaired carbohydrate, protein and fat metabolism caused by insulin resistance. One of the factors that influence the control of fasting blood sugar levels is self-management. The purpose of this study was to determine the relationship between self-management and fasting blood sugar in patients with type 2 diabetes mellitus at the Andalas Public Health Center, Padang City. This research is a descriptive correlational study with a cross sectional approach, carried out in January-August 2022 at the Andalas Health Center, Padang City. The number of samples is 44 people with the Accidental Sampling method. Univariate analysis is shown in the frequency distribution table and bivariate with Spearman's test. The results of this study showed that 50% of respondents had poor self-management. The average fasting blood sugar level was 197 mg/dl with a standard deviation of 61.3 mg/dl. There is a relationship between self-management and fasting blood sugar levels in patients with type 2 diabetes mellitus at Andalas Public Health Center, Padang City with p value = 0.000.. It is recommended to health workers to make self-management as one of the nursing interventions in controlling fasting blood sugar levels in patients with type 2 diabetes mellitus.
Analysis and assessment of the reliability of the operation process of a complex, diagnosed technical facility in 5-value logic
Authors: WOŹNIAK Marek , DUER Stanisław , ZAJKOWSKI Konrad , STAWOWY Marek , HARNIČÁROVÁ Marta , DUER Radosław
Published: December 2023

What the article talks about are the difficulties of figuring out how reliable the workings of  a complicated technological object are, especially when using a five-valued logic-based diagnostic method. The foundation for conducting dependability studies on technological objects is the utilization of prepared models that depict operational processes. The present study aims to build and provide a comprehensive description of a five-state model that characterizes the operational process of the diagnosed facility. The operational states that hold significance are the states of the object being tested, as diagnosed within the framework of 5VL-value logic. The model of the exploitation process that was constructed was further validated using simulated experiments. The outcomes of these comparative tests yield the calculated probabilities of the tested thing existing in its distinct conditions. The estimated time frames of occurrence of the recognized states in the object were determined based on the probability of occurrence of the diagnostic states, which were derived from the reliability features of the tested object.
Identifikasi Potensi Pariwisata di Kabupaten Sukabumi
Authors: Choirunisa Nurul Syifa Novita Adela
Published: December 2023

Sukabumi Regency offered a very charming natural that attracted the eyes of tourists. Due to Sukabumi District's vast natural resources, local people recognised the term GURILAPS which stands for Mountain, Jungle, Sea, Beach and River. In addition, there are many popular natural resource-based tourism sites in Sukabumi District, especially Region 7 which consists of several sub-districts; Pabuaran, Sagaranten, Curug Kembar, Cidadap, Tegal Buled, and Cidolog which can be potential as tourism sites. However, these abundant natural resources have not been fully managed. Therefore, this study was conducted to determine the tourism potential of Sukabumi District. The method used was descriptive analysis. The results of the identification can be concluded that Sukabumi Regency has abundant resources, both natural and socio-cultural resources that can be used as tourism and have the potential to be developed.
The Effects of Vitamin E Administration in Non-Alcoholic Fatty Liver Disease
Authors: Handayani Tri , Prijanti Ani Retno
Published: December 2023

Non-alcoholic fatty liver disease (NAFLD) is a liver disease which has high prevalence in the society. There is no drug that is considered to be able to effectively treat this disease until today. The treatments has wide range from modifications to diet and exercise. The role of vitamin E in the treatment of NAFLD has been studied in many researches. It has high antioxidant capacity that have the ability to decrease the level of reactive oxygen species (ROS) and prevent oxidative damage that can cause cellular senescence and apoptosis. The antioxidant properties may inhibit the progression into liver damage and may even treat hepatic fibrosis in NAFLD. It also has an anti-inflammatory role that affects various inflammatory cytokines produced in NAFLD. The use of vitamin E in non-alcoholic steatohepatitis without diabetes is advised by recent guidelines from the American Association for Study of Liver Disease (AASLD) and the European Association for the Study of Liver Disease (EASLD). In patients with non-alcoholic steatohepatitis, vitamin E can decrease oxidative stress, inhibit the pathogenesis of the disease, and be used as a therapeutic option. However, new research on the safety and efficacy of vitamin E in treating diabetic non-alcoholic steatohepatitis patients is still deemed insufficient.
Novel Vesicular Carriers: Proniosomes
Authors: Sharma Bhawana , Mishra Amul , Sharma Piush , Garg Shiv , Dwivedi Abhishekh , Rathore Savita
Published: December 2023

Vesicular systems have been receiving a lot of interest as a carrier for advanced drug delivery. Encapsulation of the drug in vesicular structures can be expected to prolong the duration of the drug in the systemic circulation and to reduce toxicity by selective up-taking. Drug delivery systems using colloidal particulate carriers such as liposomes or niosomes have proved to possess distinct advantages over conventional dosage forms because the particles can act as drug reservoirs, and can carry both hydrophilic drugs by encapsulation or hydrophobic drugs by partitioning these drugs into hydrophobic domains and modification of the particle composition or surface can adjust the drug release rate and/or the affinity for the target site. Although niosomes as a carrier have shown advantages such as being cheap and chemically stable, they are associated with problems related to physical stability such as fusion, aggregation, sedimentation and leakage on storage. All methods traditionally used for the preparation of niosomes are time-consuming and many involve specialized equipment.
Quality Assurance: Role in the Pharmaceutical Industry
Authors: Agarwal Suruchi
Published: December 2023

Quality management system is an integral part of quality assurance. The main purpose of quality standards is to provide consumer satisfaction. Quality management of pharmaceutical products was started with production premises based on the principle of good manufacturing practices (GMP) and Food and Drug Administration (FDA) regulating bodies. Quality policy controls all critical points starting from raw material, in-process check, equipment, production, packaging material, and packing of finished goods till dispatch. The goal of quality assurance is to ensure that pharmaceutical manufacturing is done with safety, identity, quality and compliance with marketing values. It describes various documentation, records, procedures, and implementation of written procedures (SOPs) to maintain uniformity for the proper functioning of the system. The main aim of quality assurance is to prevent defects rather than detection of mistakes. According to ISO, quality management focuses on providing confidence that quality management will be improved. The process of quality assurance is to identify and analyze the information and judge the quality. The principle of quality assurance is on customer focus, leadership, process approach, continual improvement, and mutual benefit between customer and company. Quality assurance is the heart and soul of quality control. It is the sum of quality control and good manufacturing practices and another related quality system. Under the quality system products designed and controlled operations are specified in written form. There is a procedure of self-inspection for the effective evaluation of pharmaceutical quality products. There is regular evaluation and analysis of deviations and incidents, out-of-specification/trends, and change control during the manufacturing of drugs. Quality assurance staff is present everywhere to monitor each activity of the organization. So, it is considered as backbone of pharma companies without this they will be unable to manufacture products
Adapting to the Dark: A Novel Adaptive Low Light Illumination Correction Algorithm for Video Sequences in Wireless Communications
Authors: Kiran Kumar Chinthakindi , Sethi Gaurav , Rawal Kirti
Published: December 2023

The lower image quality and higher noise levels of low light images can have a substantial effect on wireless communication. Images typically have less brightness, less clarity, and more picture noise in low light situations. The precision and dependability of picture-based communication may be impacted by this decline in image quality. Low light levels can be detrimental to video chats since it becomes difficult for the camera to get clear pictures of the user's face. This may lead to decreased video quality, trouble with facial recognition, and a generally worse user experience when communicating over video. Low light illumination correction algorithms are frequently made to work quickly and effectively in order to enable real-time video-based wireless communication. Correcting uneven illumination or low light in images is crucial for various fields; as such images pose challenges for human recognition, computer vision algorithms, and multimedia algorithms. An adaptive illumination correction algorithm based on a simple log transformation approach enhanced by a hyperbolic beta transformation and a logarithmic image processing is presented in this research. It has an adaptive optimization function that adjusts itself based on the image’s illumination and reflectance. Low computation and minimal parameter optimization are the hallmarks of this method. A variety of illuminated images and video sequences from various datasets are used to evaluate the suggested adaptive illumination approach. This adaptive illumination approach's experimental findings are impressive compared to those produced using prior techniques. The results reveal that the proposed system can adapt to various image-based communication and surveillance video sequences taken under various illumination conditions.
Creating web applications for online psychological experiments: A hands-on technical guide including a template
Authors: Lukács Gáspár , Haasnoot Erwin
Published: December 2023

The present tutorial provides a technical overview of how to create web applications for online psychological experiments from scratch via the HTML/CSS/JavaScript framework. This approach allows virtually unlimited flexibility in accomplishing anything in an online experiment that a regular computer (or smartphone, etc.) is capable of. Apart from offering a fast introduction for complete beginners, this tutorial may also serve as a helpful guideline for more experienced programmers and researchers. Connected to the tutorial, a specific implementation is also given via the free and open-source template project at https://github.com/gasparl/expapp, intended to be improved by the community to always follow the latest technological advancements and general good practices.
PENGGUNAAN TEKNOLOGI SEBAGAI MEDIA MEMPERLENGKAPI SEMINAR GADGET PPA MELALUI VIDEO ROLE PLAY
Authors: Cendana Wiputra , Br Sitepu Putri Lopiga , Yunita Katrina Eva
Published: December 2023

PPA ID0614 Emaus Batang Tarang merupakan Pusat Pengembangan Anak yang bernaung di bawah Gereja Persekutuan Pemberitaan Injil Kristus Jemaat Emaus Batang Tarang Kecamatan Balai Kabupaten Sanggau Kalimantan Barat, bermitra dengan Compassion East Indonesia atau yang lebih dikenal dengan Yayasan Kasih Karunia. Dalam rangka mengembangkan pengetahuan anak, mahasiswa TC hadir untuk membantu para mentor dalam mempersiapkan bahan ajar dalam bentuk video seminar mengenai gadget. Video seminar tersebut berisi edukasi tentang bahaya gadget bagi anak-anak yang ada di PPA melalui role play. Banyak hal yang mengakibatkan para siswa menjadi kecanduan terhadap gadget mereka. Pengabdian kepada Masyarakat (PKM) dirangkai selama 1 bulan melalui metode diskusi, menonton dan mencari materi terkait seminar gadget oleh beberapa mahasiswa dengan mengikuti protokol kesehatan pada masa pandemi Covid19 dan penguatan materi yang tepat secara hybrid learning. Pelaksanaan project Pengabdian kepada Masyarakat dalam membuat seminar ini diawali dengan perkenalan PPA oleh mentor kepada 5 mahasiswa Universitas Pelita Harapan dengan memanfaatkan media teknomogi yang ada yaitu aplikasi WA. Seluruh kegiatan seminar gadget telah terlaksana dengan lancar dan sesuai dengan yang diharapkan. Setiap anggota mampu memenuhi tanggung jawab dengan baik, sehingga menghasilkan kerjasama yang baik. Semua anggota merasa bahagia karena mampu memenuhi tanggung jawab yang pada awalnya dianggap terlalu berat.
PELATIHAN PEMANFAATAN DORATOON BAGI GURU MGMP PAI SMA KAB. BANDUNG UNTUK PEMBUATAN KONTEN PEMBELAJARAN
Authors: Martha Ati Suci Dian , Widowati Sri , Adrian Monterico
Published: December 2023

MGMP (Musyawarah Guru Mata Pelajaran) PAI (Pendidikan Agama Islam) adalah suatu forum atau wadah profesional guru mata pelajaran agama islam yang berada pada suatu wilayah kabupaten/kota/kecamatan/ sanggar/gugus sekolah. MGMP PAI merupakan organisasi nonstruktural yang bersifat mandiri, berasaskan kekeluargaan, dan tidak mempunyai hubungan hierarkis dengan lembaga lain. Berdasarkan Permendikbud nomor 81A tahun 2013, dinyatakan bahwa Rencana Pelaksanaan Pembelajaran (RPP) saat ini harus berbasis ICT. Hal ini tentu berdampak pada bahan ajar, demikian pula pada pelajaran Pendidikan Agama Islam (PAI). Kebutuhan akan adanya konten pembelajaran berbasis ICT menjadi utama. Namun, terdapat adanya gap kompetensi yang dimiliki pendidik di lingkungan guru-guru PAI yang tergabung dalam MGMP PAI SMA Kab. Bandung terkait teknologi literasi, penggunaan, maupun pemanfaatan alat bantu untuk konten pembelajaran berupa video yang dapat menunjang kegiatan pembelajaran. Oleh karena itu, guru-guru MGMP PAI SMA Kab. Bandung memerlukan pelatihan mengenai pemanfaatan/penggunaan tools untuk pembuatan media pembelajaran. Tim Pengabdian Masyarakat Fakultas Informatika Universitas Telkom memberikan pelatihan kepada guru-guru MGMP PAI SMA Kab. Bandung tentang pemanfaatan alat bantu Doratoon sebagai sarana untuk menghasilkan konten pembelajaran berupa video animasi. Pelatihan ini terdiri dari beberapa topik, yaitu: pembuatan teks, objek, animasi, transisi dan penambahan suara/musik.
EDUKASI TATA KELOLA DAN PENYEMBELIHAN HEWAN QURBAN SECARA SYAR’I PADA KAMPUNG TEMATIK DRUM BUJANA
Authors: Winanti Winanti , Basuki Sucipto , Kamar Karnawi , Himmy’azz Istajib Kulla , Kumoro Dwi Ferdiyatmoko Cahya , Adiyanto Adiyanto , Purno Marhaendro , Yulia Yayah , Nurasiah Nurasiah , Hasna Shoftwatun , Suwita Jaka , Jubaida Ida , Yusuf Yusuf
Published: December 2023

Educational activities on the governance of the syar'i slaughter of sacrificial animals are carried out at the At-Tauhid mosque which is the location of the Bujana Drum thematic village which is the assisted village/village of the Insan Pembangunan Indonesia University. There were 12 participants in the activity consisting of lecturers, students, heads of DKM/mosque administrators and the community. The activity begins with a request, implementation of activities, and preparation of the final report by the implementing team. The objectives of the activity include educating DKM management and the community in managing and slaughtering sacrificial animals in accordance with the sunnah. Governance that must be carried out by the DKM management and the community in slaughtering and distributing the appropriate sacrificial animals so that the DKM administrators and the community both understand correctly about the management of sacrificial animals, the qurban contract and the procedures for slaughtering, distribution of qurban meat
KONSEP FLEXIBILITY PADA INTERIOR FASILITAS PENUNJANG PENDIDIKAN DARUL HIKAM INTEGRATED SCHOOL (DHIS)
Authors: CARDIAH TITA , Firmansyah Rangga , Mulya Raja Togar , Satria Muhammad Ridho
Published: December 2023

Fasilitas pendidikan merupakan factor penting dalam menunjang keberhasilan dan target capaian pembelajaran. Darul Hikam Integrated School (DHIS) – Primary sebagai sekolah yang menjunjung tinggi nilainilai Akhlak dan mengembangkan kreativitas siswa, sehingga membutuhkan dukungan fasilitas pendidkan yang sesuai dengan target pembelajaran, program Pendidikan dan tentunya visi dan misi sekolah. Tujuan pengabdian masyarakat ini adalah untuk membantu menyelesaikan permasalahan ruang atau fasilitas yang ada di Darul Hikam Integrated School (DHIS) – Primary untuk di lakukan penataan ulang yang menerapkan konsep penataan flexibility ruang interior pada fasilitas Pendidikan. Hasil yang diharapakan dari kegiatan ini adalah Rekomendasi desain yang menjawab pemasalahan pada fasilitas Pendidikan di Darul Hikam Integrated School (DHIS) – Primary.  Metoda yang digunakan pada penelitian ini adalah pemecahan masalah berdasarakn data eksiting dan melanjutkan menghasilkan rekomndasi desain. Adapun tahapan kegiatan adalah pengumpulan data awal, survey data eksisting, Analisa data, presentasi kepada mitra, pengembangan desain dan terakhir adalah presentasi atau diseminasi hasil kegiatan. Batasan/lingkup objek pembahasan  (sesuai usulan mitra) adalah fasilitas penunjang yang meliputi ruang Hall, lobby, ruang tunggu siswa, reading corner, ruang drop makan siang dan jalur sirkulasi.
PARTISIPASI ORANGTUA DALAM PELATIHAN BAHASA INGGRIS ANAK-ANAK SANGGAR ANGKRINGAN BOCAH SINAU
Authors: Wardhani M kusuma
Published: December 2023

Sanggar Angkringan Bocah Sinau di Yogyakarta yang beranggotakan anak-anak SD kelas 4-6, sudah berjalan selama 6 tahun. Kegiatan belajar non formal yang dilayani oleh para mahasiswa magang ini, diperuntukkan bagi anak-anak yang kurang beruntung secara ekonomi, namun mempunyai semangat belajar tinggi. Tetapi  pandemi menghentikan semua kegiatan ini. Permasalahan muncul, orang-tua gelisah karena  pendidikan anak tidak terpantau, tidak mempunyai dana lebih untuk pendidikan, serta mahasiswa magang yang biasanya mengajar, pulang ke daerah masing-masing. Solusi masalah ini, adalah program pengabdian masyarakat, yang dilakukan selama 1 tahun  dengan kegiatan penyuluhan pendidikan bagi orang-tua serta pelatihan Bahasa Inggris bagi anak-anak. Metode pelaksanaan program dimulai dari : diskusi dengan pihak sanggar ;  kunjungan ke lokasi;  menentukan solusi  kegiatan yang tepat; menyusun jadwal; pelaksanaan kegiatan; evaluasi serta  tindak lanjut.  Kegiatan  selama Juni 2022 s/d Mei 2023 berupa 3 kali penyuluhan untuk orang tua, serta 12 kali pelatihan Bahasa Inggris bagi anak-anak, yang dilakukan secara daring. Hasil dari kegiatan ini ; orang tua  senang dan antusias mengikuti program tanpa perlu mengeluarkan biaya, orang-tua belajar cara mendampingi dan memotivasi  anak belajar Bahasa inggris dengan berbagai media,  anak-anak mengalami peningkatan yang signifikan dalam kemampuan berbahasa inggris. Orang tua  berharap selanjutnya ada juga program pelajaran Bahasa Inggris untuk orang tua.

Kata kunci : pelatihan, Bahasa Inggris, sanggar
PENINGKATAN KAPASITAS IBU PKK BERWIRAUSAHA MELALUI DIGITAL MARKETING DI KELURAHAN SEMEMI KOTA SURABAYA.
Authors: Astutik Ari , Probowati Yeni , Heryyanto Asep
Published: December 2023

Anggota PKK RT 7 RW 2 yang berada di Kelurahan Sememi Kecamatan Benowo Kota Surabaya adalah ibu-ibu yang hanya mempunyai kegiatan arisan dan simpan pinjam. Oleh karena itu dengan PKM ini kami akan mambantu memulai usaha makanan ringan agar para ibu PKK mendapatkan penghasilan untuk mengisi waktu senggangnya agar semakin produktif. Permasalahan pertama ialah mitra tidak mempunyai alat produksi yang modern dan higienis. Kedua, tidak berpengalaman dalam memilih bahan pengemasan dan mendesain label yang menarik. Ketiga, mitra belum mampu membuat rencana bisnis, pengembangan produksi dan pembagian kerja. Keempat, mitra belum pernah memasarkan secara online dengan memaksimalkan media teknologi informasi dalam aktivitas pemasaran. Solusi yang akan diberikan antara lain pengadaan perlengkapan produksi dan Pengadaan bahan kemasan yang modern dan higienis. Kemudian pelatihan dan pendampingan dalam membuat dan mendesain label produk yang menarik dengan bahasa Indonesia dan inggris. Dalam manajemen usaha akan diadakan pelatihan dan pendampingan dalam membuat rencana bisnis, pengembangan produksi dan pendampingan dalam pembuatan pembagian kerja. Dan yang terakhir dalam bidang pemasaran solusi yang ditawarkan ialah pelatihan dan pendampingan pembuatan akun media teknologi informasi untuk meningkatkan jangkauan pasar seperti Whatsaap, instagram, facebook dan GrabFood. Sebagai hasilnya ibu-ibu PKK RT 7 mempunyai UMKM dengan produk Healthy Banana Snack Cake.
Program Pengenalan Jurusan Teknik Melalui Aktivitas Fun Science Experiment Bagi Siswa MTS Darul Hikmah
Authors: RYANU HARFAN HIAN , Pramudita Aloysius Adya , Sudjai Miftadi
Published: December 2023

Madrasah Tsanawiyah (MTS) merupakan sebuah penyelenggara pendidikan formal setingkat sekolah menengah pertama dengan penekanan lebih banyak pada muatan Pendidikan Agama Islam. Siswa MTS umumnya memiliki eksposure yang rendah terhadap dunia sains dan teknik sehingga sangat sedikit/jarang siswa madrasah yang melanjutkan pendidikan terutama perkuliahan pada jurusan Teknik. Kegiatan pengabdian masyarakat kali ini dengan judul “Pengenalan Jurusan Teknik Melalui Aktivitas Fun Science Experiment Bagi Siswa MTS Darul Hikmah” bertujuan meningkatkan peminatan siswa sejak dini terhadap dunia sains dan keilmuan teknik. Metode yang dilakukan adalah project-based learning dimana siswa terlibat dalam kegiatan merancang kipas angin dan alat pembersih lantai otomatis dengan menggunakan baterai dan mikrokontroler sederhana. Sebanyak 22 siswa dari kelas 7 di MTS Darul Hikmah dilibatkan dalam kegiatan ini.

Kegiatan ini memperoleh respons positif dari masyarakat sasar. Sebanyak 100% peserta merasa sangat puas terhadap output kegiatan, dan 100% peserta menilai kegiatan sangat bermanfaat. Sebanyak 90.5% peserta menilai kegiatan membantu memberikan aspirasi untuk cita-cita kedepannya, sedangkan sebanyak 9.5% peserta menilai kegiatan tidak membantu. Selain itu, sebanyak 85.7% merasa kegiatan ini mendorong siswa untuk mempelajari lebih lanjut terhadap sains dan keteknikan, sedangkan 14.3% merasa kegiatan tidak memberikan dampak apapun. Dengan begitu, kegiatan ini dapat disimpulkan memiliki output sesuai target yang diharapkan.
PELATIHAN FOTOGRAFI SEBAGAI MEDIA PEMBELAJARAN PENGENALAN BENTUK DASAR VISUAL PADA GURU TK AL MUMIN ASSIDIQIYAH
Authors: Desintha Siti , Aditya Dimas Krisna , Fitriani Fetty
Published: December 2023

Media pembelajaran bagi anak-anak usia dini memiliki berbagai macam jenis dan fungsi. Pada usia tersebut merupakan masa dimana anak memiliki daya tangkap yang sangat baik. Selama ini media pembelajaran untuk pengenalan bentuk dasar yang diterapkan oleh TK Al Mumin Assidiqiyah belum mengadaptasi fotografi. Mereka masih menggunakan media illustrasi untuk menggenalkan bentuk dasar kepada anak didiknya. Menurut Edgar Dale, gambar fotografi dapat mengubah tahap-tahap pembelajaran, dari lambang kata (verbal symbol) beralih kepada tahapan yang lebih kongkret yaitu lambang visual (visual symbols). Sehingga siswa dapat melihat visual lain yang realistis dan memberikan alternatif media pembelajaran lain . Selain itu apabila hendak menggunakan media fotografi maka gambar yang dihasilkan harus memenuhi unsur bentuk dan artistiknya.

Berdasarkan hal tersebut tim PKM bersama dengan pihak TK selaku masyarakat sasar dan mitra merumuskan ide untuk memberikan pelatihan kepada guru-guru tentang bagaimana menggenalkan bentuk dasar visual melalui teknik fotografi dalam membantu kegiatan belajar mengajar. Kegiatan pelatihan ini dapat mengembangkan kompetensi dan profesionalisme para guru dalam mengembangan media pembeslajaran agar lebih menarik bagi siswa
PEMBERDAYAAN MASYARAKAT : PARENTING SKILL UNTUK GENERASI ALPHA DI ERA DIGITAL PADA PAUD DAHLIA SEMEMI
Authors: Tyas Fifin Dwi , Mardiyanti Ressy , Fithri Nur Hidayatul , Umma Alfira Ayu Talita , Jazuli Mochamad Ahzam
Published: December 2023

PPT Dahlia adalah sekolahan untuk anak-anak usia dini yang bertempat di daerah sememi RT/RW : 1 / 4, Desa Kelurahan: Sememi, Kecamatan : Benowo. PPT Dahlia peserta didiknya ada 31 laki-laki dan 23 perempuan jadi total 54 peserta didik. Dari observasi dan wawancara yang telah dilakukan menunjukkan bahwa orang tua yang bersangkutan juga tidak bisa berbuat banyak atas kondisi yang sedang berlangsung. Permasalahan Mitra sebagian besar para orang tua kurang bisa  mengontrol anak mereka dalam menggunakan gadget serta kurang bisa mengawasi anak-anak ketika melihat konten-konten atau tayangan internet. Metode Pelaksanaan adalah berbasis pemberdayaan masyarakat yang berbasis kegiatan pelatihan Parenting skill   di PPT Dahlia Sememi. Rencana Kegiatan bentuk kegiatan 1) Pelatihan Parenting skill   tentang  penggunaan gadget yang ramah anak, 2) Pelatihan penting paham akan tumbuh kembang anak dalam usia golden age, 3) Pelatihan Parenting skill   tentang pola asuh yang baik untuk anak-anak dimasa generasi alpha. Tujuan Pengabdian agar orang  tua  dapat  memberikan  batasan  waktu dalam penggunaan  gadget,  melatih   anak   untuk   bertanggung   jawab   atas   penggunaan   gadget selain itu dapat mencarikan alat permainan edukatif yang menarik bagi anak sebagai pengganti gadget. Hasil Pengabdian orang tua lebih memahami dan akan menetapkan batasan waktu bagi anak untuk menggunakan gadget agar anak tidak lupa waktu yang diperlukan.