bluuebunny/crossref_metadata_2025 huggingface dataset:
A COMPARATIVE STUDY OF SURGICAL TREATMENT VERSUS CONSERVATIVE TREATMENT OF VOCAL CORD NODULES IN TERTIARY CARE HOSPITAL
Authors: Khatua Indranil , Bose Alokendu , Kundu Indranath , Jana Debarshi
Published: December 2020

Background: Vocal cord nodules are bilateral, benign, and callous like growths of the mid portion of the membranous vocal folds. They are of variable size and characterised histologically by thickening of epithelium with a variable degree of inflammation in the underlying superficial lamina propria1. They characteristically produced hoarseness, discomfort and an unstable voice when speaking or singing.
AIMS: Comparison between post treatment (surgical and conservative treatment groups) voice quality of the two groups and post treatment status of nodules in both the groups.
MATERIAL AND METHODS: Outpatient department and Indoor wards of Department of ENT and Head Neck surgery, R. G Kar Medical College. Patients attending ENT OPD of R G Kar Medical College during the Study period were the study population. Sample size was atleast 50 Patients.
RESULT: In group-A, 4(23.5%) patients were regressing and 13(76.5%) patients had resolve. In group-B, 4(12.1%) patients were persisting and 29(87.9%) patients were regressing. Association of post Rx VCN vs. group was statistically significant (p<0.001).
CONCLUSION: Vocal fold nodule is one of the most frequent benign laryngeal lesions, influencing the quality of life of those affected by them, primarily the vocal production. Despite being a well-established therapy in conjunction with surgery, speech therapy alone may also be effective in treating these lesions.
SCREENING FOR CONGENITAL HYPOTHYROIDISM WITH UMBILCAL CORD BLOOD TSH LEVEL ‘AN EXPERIENCE FROM A TERTIARY CARE CENTER'
Authors: Modi Rohan , Mod Harsh , Phalak Aabha , Parikh Rutvik , Kavad Vilas , Prajapati Baldev S
Published: December 2020

BACKGROUND:- Congenital hypothyroidism (CH) is the most common preventable cause of mental retardation. Screening for congenital hypothyroidism can be helpful in preventing mental retardation among general population. Umbilical cord blood TSH (CBTSH) estimation has been universally accepted and is one of the most cost effective screening programs in the field of preventive medicine and public health. AIMS AND OBJECTIVES:- This study was aimed to find the effectiveness of cord blood TSH as a screening tool for congenital hypothyroidism. MATERIALS AND METHODS:- This hospital based cross sectional study was conducted at GCS Medical College Hospital & Research Centre, Ahmedabad, over a period of one year in 1687 neonates. All newborns delivered at the institute were subjected to cord blood TSH level estimation and a repeat Serum TSH estimation was done at or after 72 hours of life. Diagnosis of congenital hypothyroidism is confirmed postnatally by standard Serum TSH value cut offs as per age. Data collected and statistically analysed. RESULTS:- Out of 1687 neonates born during the study period, 1548 formed the study group. 805 (52%) were males and 743(48%) were females. The birth weight of babies ranged from 850 gms to 4300 gms. The value of CBTSH varied from 1.3mIU/L to 101.4mIU/L with mean CBTSH of 7.21mIU/L. 28(1.8%) babies had CBTSH levels >20mIU/L. Out of which four were later diagnosed to have congenital hypothyroidism. All four had CBTSH levels >20mIU/L. All other neonates with CBTSH levels less than 20mIU/L were found to have normal screening later postnatally. CONCLUSION:- The current study concludes that cord blood TSH is a sensitive marker to screen for congenital hypothyroidism in neonates. A cut off value of cord blood TSH >20mIU/ml can be used for screening purpose.
RETROSPECTIVE STUDY OF OPHTHALMIC CARE IN HIGH PROFILE PATIENT SCENARIO
Authors: Gore Varshav , Agrawal Mamta , Choudhary Ayushi
Published: December 2020

BACKGROUND
VIP syndrome is a condition in which high profile people are shown to experience adverse treatment effects even in the hands of skilled physicians or surgeons in absence of any other potentially complicating risk factor. High profile patients can be categorized into three groups: Public figures, Relatives, and Colleagues and other doctors. Since ophthalmological surgeries are micro surgeries requiring precise measurements and techniques, any secondary influence over the surgeon’s decision making powers, due to the presence of elite patients, has an undesirably affect. This is a retrospective analysis done after the surprising finding that correlates with many of my colleagues and we came to common conclusion about difference in approach towards known and unknown patients.
METHOD
100 senior doctors belonging to different departments of a tertiary health care were inquired about their patients and the complications they faced while treating high profile patients by filling a questionnaire on the basis of their experience.
RESULTS
90% of the doctors do categorize their patients into high profile patients, 80% of these doctors who faced complications had changed their routine treatment protocol. 93% of the doctors were cautious while treating these patients. 98% of the doctors agree with the bias present while treating high profile patients and consider the need to highlight VIP syndrome.
CONCLUSION
It is important to follow routine fixed protocol, no using new instruments or techniques and not to categorize any patient as high profile, manage such patients cautiously but without getting overcautious and maintaining confidentiality and privacy
FNAC AS A TOOL IN THE DIAGNOSIS OF BCG INDUCED LYMPHADENITIS-AN INSTITUTIONAL EXPERIENCE.
Authors: Sravani P. , Bhavani C. , Naik V. Sivasankara , Neeraja M.
Published: December 2020

Background:
Tuberculosis is a major cause of mobility and mortality in developing countries including India.BCG vaccine has been in use since 1921 and is considered to be one of the safest vaccines with self limited regional Lymphadenopathy being the most common complication.
Objectives:
The present study aims toevaluate the efficacy and cytomorphological patterns of BCG lymphadenitis.
Materials & methods:
This cross-sectional study was conducted in the Department of Pathology of
Government Medical College / Government General Hospital, Anantapuramu,
during the period January 2017 to December 2019. Patients with suspected
ipsilaterallymphnodal enlargement after BCG vaccination and age ranging from two months to two years , who were referred for FNAC, were included in this
study. FNAs of 17 patients were studied in the present study. FNAC was performed
by using a 10 mL syringe with a 23 g needle. Smears were stained with H& E stain (Haematoxylin and Eosin)and ZN ( Ziehl –nelson )stain.The data collected was entered into an Excelsheet and analyzed.
Results:
Cytology slides prepared were studied, interpreted, and the diagnosis made was
analyzed.A total of 17 cases were studied with the mean age of 6.24 months. Majority of the patients were males seen in 64.71% of cases. Ipsilateral Axillary lymphnode was the most common site involved seen in 82.35% cases.Pus was aspirated in 76.47% of cases.On microscopic examination diffuse necrosis with degenerated cellswas the predominant cytological pattern seen in nine (52.94%) cases. ZN stain showed Acid fast bacilli positivity in 15 cases.
Conclusion:
FNA cytology combined with clinical correlation is useful for diagnosis and management of BCG lymphadenitis.
A STUDY ON THE BACTERIOLOGICAL PROFILE OF URINARY TRACT INFECTION INADULTS AND THEIR ANTIMICROBIAL SENSITIVITY PATTERN IN DMCH, LAHERIASARAI, BIHAR
Authors: Jha Neha , Prasad R. S. , Jha P. N. , Jana Debarshi
Published: December 2020

Background: Urinary tract infection is one of the most common bacterial infections in humans and a major cause of morbidity. The etiology of UTI and the antimicrobial sensitivity pattern varies with the widespread availability of antimicrobial agents; UTI has become difficult to treat because of appearance of pathogens with increasing resistance to antimicrobial agents.
Methods: A descriptive study done during January 2020 to June 2020. All positive urine culture and sensitivity reports of males and females aged 20-70years were included. A total of 373 positive urine culture cases were taken from the culture and sensitivity register from Microbiology department and details were entered using a questionnaire.
Results: Out of 373 adults, males were 137 (36.7%) and females were 236 (63.3%). E. coli (74.3 %) was the most common organism, followed by Klebsiella (15.8%), Enterococcus, Pseudomonas and Staphylococcus. The incidence of UTI was more in patients in the age group of 60-70years. E. coli and Klebsiella were sensitive to Amikacin (97.1%), Nitrofurantoin (90.7%), Gentamycin and Imipenem. Both organisms were resistant to Ampicillin (>90%).
Conclusions: In this study, females were mostly affected and the most common organisms were E.Coli and Klebsiella. These organisms were most sensitive to Amikacin, Nitrofurantoin and resistant predominantly to Ampicillin. The sensitivity and resistance pattern of uropathogens to common antimicrobial agents must be taken into account when selecting treatment plans for UTI.
DERMATOGLYPHIC STUDY OF BETA THALASSEMIA IN A TERTIARY CARE HOSPITAL – A CASE CONTROL STUDY
Authors: Chhatui Oindrila , Mukherjee Pranab , Bharati Premananda , Jana Debarshi
Published: December 2020

BACKGROUND: The term “thalassemia” was coined by Whipple and Bradford in 1932, in their classical paper of pathology of the condition. Thalassemia is a heterogenous group of genetic disorder affecting haemoglobin synthesis which results from a reduced rate of production of one or more globin chains of haemoglobin.
AIM: The current study will try to find out the dermatoglyphic correlation between thalassemic children and children not having thalassemia in respect of gender as well as bilateral asymmetry.
METHODS: The sample for the present case control study was collected from Thalassemia unit, under Paediatric department at R.G. Kar Medical College and Hospital, Kolkata. Among 204 individuals- 102 are cases, who are diagnosed Beta Thalassemia patients up to 12 yrs of age and 102 are normal children upto 12yrs of age taken as control groups. Among 102 in each case and control groups, 51 are male and 51 are female individuals.
RESULT: Association of control male and Beta thalassemic male vs. Triradial count right was statistically significant (p<0.0001). Association of control male and Beta thalassemic male vs. Triradial count left was statistically significant (p<0.0001).
CONCLUSION: In female thalassemia patients, there was complete absence of radial loops. But, significant lower incidence of radial loops of left hand was observed in male Beta thalassemics than the control group.
PLATELET CONCENTRATES- PREPARATION PROTOCOLS AND RECENT ADVANCES
Authors: Fulsundar Prathamesh , More Vijaysinh
Published: December 2020

Autologous blood derivatives are surgical biologic additive that are prepared by manipulation of autologous blood. Platelet rich fibrin is one of the most commonly used blood derivatives in dentistry. Blood derivatives have several advantages such as being 100% autogenous, cost effective, less time consuming, simple to perform and with superior & prolonged release of growth factors.
Since inception there has been evolution of various techniques, in-depth research regarding its biological actions, clinical applications. Several modifications have been advocated in the conventional protocol like the advanced PRF, injectable PRF, PRF lysate and Titanium-prepared PRF.
Hence, the aim of this article is to review various types and properties of blood derivatives and the advancement in the PRF technology since its inception.
Furthermore, platelet concentrates are safe, reliable and cost-effective means to accelerate tissue healing and for improving the efficiency of tissue repair after injury.
OCULAR DOPPLER IN BRAIN STROKE PATIENTS TO AID IN EARLY DIAGNOSIS OF EYE STROKE
Authors: Ramakrishnan Reshma , Amberkar Sayali , Gandhi Priyanka
Published: December 2020

Ischemic stroke presents an exceptionally large medical burden given that it is one of the leading causes of morbidity and mortality and is associated with high healthcare expenditures. A 51 years old female, case of right MCA territory infarct was referred from Medicine department to ophthalmic OPD with transient loss of vision in right eye since 2 days after the episode of stroke. She was hypertensive since 4 years. On slit lamp evaluation, anterior segment revealed immature senile cataract in both the eyes. Grade II RAPD was seen in right eye. Right eye fundus examination revealed a inferior hemiretinal artery occlusion and grade III hypertensive retinopathic changes. Left eye fundus examination showed grade III hypertensive retinopathic changes.
Two dimensional echocardiographic study of cardiac valves and aorta and carotid doppler assist in locating embolic sources of retinal occlusions along with ocular doppler. Therefore, it is necessary to screen all patients who present in the emergency room with stroke or history of stroke to provide early diagnosis and improve visual prognosis.
We would also like to emphasise that there is a need to spread awareness among all physicians for the need of routine ophthalmic consult for all hypertensive patients. In stroke patients, an ophthalmic consult should be done on the day of stroke for better visual care and prognosis. If ocular doppler along with carotid doppler is introduced as primary investigation in emergency room, it might help in early diagnosis, early intervention and aid in prevention of visual loss.
CARDIOVASCULAR RISK IN PATIENTS WITH SUBCLINICAL HYPOTHYROIDISM
Authors: Mehta Anil Kumar , Jana Debarshi
Published: December 2020

Thyroid hormone regulate every organ system in our body. Metabolic parameters, including lipoprotein metabolism and cardiovascular risk factors like obesity, glucose intolerance or type 2 diabetes, dyslipidemia and hypertension are all influenced by serum TSH level in our body. Several reports have demonstrated a positive correlation between TSH levels and cardiovascular risk factors. C-reactive proteins is one of the markers of inflammation and also considered to be the predictor of cardiovascular disease and may be helpful in the assessment of future development of cardiovascular abnormalities in subclinical hypothyroidism.
Methods: Recently diagnosed 71 subclinical hypothyroidism patients were enrolled in the study and compared with 63 healthy individuals. Patients were divided into two groups on the basis of thyroid stimulating hormone (TSH) concentration. Thyroid profile (TSH, free thyroxine, triiodothyroinine) and C-reactive protein were estimated by enzyme-linked immunosorbent assay. Total cholesterol (TC), triglycerides (TG), and high-density lipoprotein-cholesterol were estimated in the study population by a spectrophotometric method, and low-density lipoprotein-cholesterol (LDL-C) was measured by the Friedewald formula.
Results and Conclusion: Altered lipid profile, as well as higher concentrations of C-reactive protein, was observed in subclinical hypothyroidism patients as compared to controls. Higher concentration of TC, TG, and LDL was observed in subclinical hypothyroidism patients while the concentration of high-density lipoprotein was lower in patients with subclinical hypothyroidism. The elevated concentration of C-reactive protein was also observed in the patient group. Patients having TSH >10 μIU/ml have a higher risk of developing cardiovascular disease compared to patients having TSH <10 μIU/ml and increasing concentration of C-reactive protein along with LDL-C may to cardiovascular abnormality.
COMPLICATIONS AND MANAGEMENT OF ENDOSCOPIC SEPTOPLASTY AT A TERTIARY CARE CENTER IN INDIA
Authors: Chhatbar Y B , Sharma Suktara , Patel Prachi M , Bavarva Drashty D , Patel Vaibhav B
Published: December 2020

Introduction: Septoplasty for nasal septal deviation is one of the most commonly performed surgeries by the otolaryngologist. Though various surgical techniques have evolved for correction of a deviated septum, complications are still common. Method: A prospective study of 90 patients of symptomatic nasal septal deviation was done to investigate for development of complications after endoscopic septoplasty. Complications were catagorised into early, occurring within 7 days and late, usually detected within three months after surgery. Results; Most common early complication was haemorrhage seen in overall 16.66% of patients. 6.66% had primary hemorrhage during surgery and 8.88% had reactionary hemorrhage within 24 hours of surgery. Secondary hemorrhage and septal hematoma was rare(1.1%) . Most common late complication was persistence of subjective symptom of nasal blockage(15.55%) followed by nasal synache(5.55%). Septal perforation and vestibular stenosis are less common(1.1%). CSF leak, saddle nose, nasal tip ptosis or any ocular complications were not seen in any patient. Conclusion:. Meticulous preoperative planning with precise surgical techniques during endoscopic septoplasty can reduce the risk of complications that may have a profound effect on the functional and aesthetic aspects of a person’s life.
A COMPARATIVE STUDY OF SURGICAL TREATMENT VERSUS CONSERVATIVE TREATMENT OF VOCAL CORD NODULES IN TERTIARY CARE HOSPITAL.
Authors: Khatua Indranil , Bose Alokendu , Kundu Indranath , Jana Debarshi
Published: December 2020

Background: Vocal cord nodules are bilateral, benign, and callous like growths of the mid portion of the membranous vocal folds. They are of variable size and characterised histologically by thickening of epithelium with a variable degree of inflammation in the underlying superficial lamina propria1. They characteristically produced hoarseness, discomfort and an unstable voice when speaking or singing.
AIMS: Comparison between post treatment (surgical and conservative treatment groups) voice quality of the two groups and post treatment status of nodules in both the groups.
MATERIAL AND METHODS: Outpatient department and Indoor wards of Department of ENT and Head Neck surgery, R. G Kar Medical College. Patients attending ENT OPD of R G Kar Medical College during the Study period were the study population. Sample size was atleast 50 Patients.
RESULT: In group-A, 4(23.5%) patients were regressing and 13(76.5%) patients had resolve. In group-B, 4(12.1%) patients were persisting and 29(87.9%) patients were regressing. Association of post Rx VCN vs. group was statistically significant (p<0.001).
CONCLUSION: Vocal fold nodule is one of the most frequent benign laryngeal lesions, influencing the quality of life of those affected by them, primarily the vocal production. Despite being a well-established therapy in conjunction with surgery, speech therapy alone may also be effective in treating these lesions.
REFERENCE RANGE OF POST-EXERCISE HEART RATE AFTER THREE-MINUTE STEP TEST FOR ASSESSMENT OF CARDIORESPIRATORY FITNESS IN CHILDREN
Authors: Thakrar Gira , Shah Nehal
Published: December 2020

Cardiorespiratory ﬁtness which is a key parameter of children’s health, should be an important aspect in evaluation and promotion of physical activity and healthy lifestyle. This study aimed to develop a reference range of post-exercise HR (HRpost-ex) after a 3-min step test used to screen the cardiorespiratory ﬁtness of 6- to 9-year-old children (≥6 years to <9 years). The study included 489 children (245 boys and 244 girls) of ages 6–9 years from different schools of various cities across Gujarat, India. These children were subjected to the 3-min Kasch Pulse Recovery Test (KPR Test). The reference range for the classification of cardiorespiratory fitness was developed based on the age-specific percentile distribution of HR post-ex in 6- to 9-year-old children. This study showed that the 3-min KPR Test is easy to perform by school-age children. As such, it can constitute a useful tool for health promoters and educators. The presented age- and gender-specific reference range of HR post-ex enables the assessment and monitoring of submaximal exercise-induced changes in the cardiovascular system and, consequently, the physical fitness of a given individual.
ROLE OF MRI IN PRIMARY BONE TUMORS AND ASSESSING THEIR LOCAL SPREAD
Authors: Sachdev Namrita , Singh Yashvant , Vani Kavita , Jain Rushil , Sethi Dinesh
Published: December 2020

Background Radiographs are the most valuable modality for diagnosis of bone tumors, however MRI is emerging as the modality of choice for assessing local spread of tumor.
Objective To assess role of MRI in local spread of tumor and comparison to surgical & histo-pathological results.
Results 47 patients ( age 10-73 years with mean age of 38 years) were studied from May 2018 to November 2019. There were 26 males and 21 females, 9 patients were excluded as no operative results were available. Out of the 38 total cases, 11 were osteosarcoma, 7 were Ewing’s sarcoma, 7 were GCT, 6 were Chondrosarcoma, 2 Osteochondroma, 1 PNET, 1 ABC, 1 Hemangioma, 1 Chordoma and 1 Multiple myeloma. Cortical break was detected in 29 patients on MRI with 2 false positive cases showing 93% accuracy. Medulla involvement was detected in 34/35 patients (97%). Neuro-vascular involvement was detected in 9 patients on MRI with 1 false positive cases showing 88.9% accuracy. Joint involvement was detected in 13 patients on MRI with 2 false positive cases showing 84.6% accuracy. All 4 cases of skip lesion (100%) were detected on MRI.
Conclusion MRI is the modality of choice to assess for local spread of bone tumors.
BIPLANAR OPEN WEDGE HIGH TIBIAL OSTEOTOMY IN THE MEDIAL COMPARTMENT OSTEOARTHRITIS OF THE KNEE JOINT: COMPARISON BETWEEN THE AESCULAAND TOMOFIX PLATE AT ORTHOPAEDICS DEPARTMENT OF JLNMCH, BHAGALPUR, BIHAR.
Authors: Singh Rakesh Ramdayal , Kumar Yogesh , Azam Maseeh , Singh D. K. , Jana Debarshi
Published: December 2020

Background: The purpose of this study was to compare the results of Aescula and TomoFix plates used for biplanar open wedgehigh tibial osteotomy in medial osteoarthritis of the knee joint with varus deformity. Methods: A consecutive series of 50 cases of biplanar open wedge high tibial osteotomy were evaluated retrospectively. GroupA contained 25 cases treated by using the Aescula plate, and group T contained 25 cases treated by using the TomoFix plate. Full weight-bearing was permitted at 6 weeks after surgery in group A and at 2 weeks in group T. Clinical evaluations were performed at the final follow-up by using postoperative knee scores and functional scores. Radiographic analysis included postoperative mechanical femur-tibia angle, change in posterior tibial slope angle, and complications related to implants. The mean follow-up periods were 30 months in group A and 26 months in group T. Results: The knee and functional scores were improved at the final follow-up in both groups (p< 0.05), but no differences wereobserved between the two groups (p> 0.05). An acceptable correction angle was obtained in 52% of group A and in 84% of group T (p = 0.015). Change in posterior tibial slope angle was larger in group A than in group T (p< 0.001), showing better maintenance of posterior tibial slope in group T. In group A, there were 3 cases of screw loosening and 4 cases of delayed union. In addition, there were residual varus deformities in 7 cases (6 in group A and 1 in group T). Conclusions: This study shows that firm fixation using a TomoFix plate for open wedge high tibial osteotomy produces better radiologic results and a low complication rate than those of the Aescula spacer plate.
THE IMPACT OF ASTHMAAND ITS MEDICATIONS ON DENTAL CARIES STATUS AND STREPTOCOCCUS MUTANS COUNT IN CHILDREN: A CROSS-SECTIONAL STUDY
Authors: Upadhyay Sneha , Bhavthankar Jyoti , Mandale Mandakini , Kaorey Nivedita
Published: December 2020

Background: Asthma and its medications have been linked to oral diseases in asthmatic children. Aim: Assessment of the dental caries status, salivary Streptococcus mutans count and S. mutans colony score in children receiving inhaled anti asthmatic medications and their comparison in healthy children Material and Method: A cross-sectional study was performed on 40 asthmatic children and 40 healthy children in the age group of 6-14 years. DMFT/deft indices were calculated and saliva samples were collected. Diluted saliva was inoculated on MSB agar plates. S. mutans count and colony score were analysed after 24-48 hours of inoculation. Results: Statistically significant difference was observed in the mean DMFT/deft index, salivary S. mutans load and S. mutans colony score in children of the asthmatic group and control group. Conclusion: Prevalence of dental caries and cariogenic bacteria is higher in asthmatic children.
COMPARISON OF EFFICACY AND SAFETY OF TENELIGLIPTIN VERSUS SITAGLIPTIN AS ADD ON TO METFORMIN IN TYPE 2 DIABETES MELLITUS AT JLNMC, BHAGALPUR, BIHAR
Authors: Pandit Mrityunjay Kumar , Ahmad Iftekhar , Kumar Jeetendra , Jana Debarshi
Published: December 2020

Introduction
Diabetes mellitus (DM) is a leading cause of mortality and an increasing health burden with a prevalence of 8.3% globally and 9.1% in India (IDF). Prevention of complications and improving quality of life are the principle goals in its management. DPP-4 inhibitors have a potential vasoprotective effect mediated by stromal cell derived factor-1a. Teneligliptin a novel, highly selective, more potent agent compared to Sitagliptin provides sustained glycaemic control, decreases cardiovascular complications, has additional beneficial pleiotropic metabolic effects and also safe in renal impairment.
Objective
To evaluate the glycaemic and non-glycaemic effects of Teneligliptin vs Sitagliptin as add on therapy to metformin.
Materials and methods
60 subjects with T2DM who failed to achieve glycaemic control with metformin (500mg TID) alone for 3 months were randomized in 1:1 ratio to receive Teneligliptin 20mg OD and Sitagliptin 100mg OD as add on therapy. Patients were followed up at 4, 8 and 12 weeks for glycaemic and non-glycaemic effects. Adverse drug reactions (ADRs), if any were recorded and graded according to severity.
Results
There was a statistically significant decrease in FBS (p<0.05, p<0.001) and PPBS (p<0.01, p<0.001) in patients treated with Teneligliptin on week 8 & week 12 from baseline compared to those treated with Sitagliptin. The reduction in HbA1c (p<0.0001), LDL-CH (p<0.0001) & TC (p<0.001) on week 12 from baseline was also significantly more in the Teneligliptin group.
Conclusion
Teneligliptin may be an effective and safe treatment option in reducing both glycaemic and non-glycaemic parameters as an add-on therapy in Type 2 DM with good patient tolerability.
A RARE CASE OF HEMIPLEGIA
Authors: Rajeswari Valeti , Karthik Kolluru V D , Pravallika Srinivasula Sriranga
Published: December 2020

Honey bee sting induced Cerebral infarction is a rare entity .
We report a case of 55year old male presented with anaphylactic shock following honey bee sting along with weakness of left side of the body and the face .
He was managed with anti histaminics, adrenaline injections, Intravenous fluids , vasopressors , anti platelets and anticoagulants .
COMPARATIVE EVALUATION OF THE EFFICACY AND TOLERABILITY OF ITOPRIDE HYDROCHLORIDE AND DOMPERIDONE IN PATIENTS WITH NONULCER DYSPEPSIAAT JLNMC, BHAGALPUR, BIHAR
Authors: Pandit Mrityunjay Kumar , Kumar Jeetendra , Ahmad Iftekhar , Jana Debarshi
Published: December 2020

Background :Prokinetic drugs are widely used for treatment of non-ulcer dyspepsia (NUD).
Aims and Objectives : To assess the efficacy and tolerability of a new prokinetic agent, itopride hydrochloride in patients of NUD and compare it with domperidone.
Methods : Fifty-six patients who fulfilled the inclusion and exclusion criteria were enrolled in the study. Patients underwent upper gastrointestinal endoscopy to rule out organic pathology as a cause for their symptoms. The patient’s symptoms were graded on a 4-point scale (0 to 3) at the beginning of treatment and at the end of Week-one and Week-two Patients were randomly allocated to receive either one tablet of itopride hydrochloride 50mg three times daily or one tablet of domperidone 10mg three times daily for two weeks. Pre-treatment and post-treatment hemogram, liver function and renal function tests, prolactin level and ECG were done in all patients. The response to therapy was evaluated by assessing the relief of symptoms at the end of two weeks on a 5 -point scale. Statistical analysis was done using two-tailed paired t-test; Wilcoxon matched pairs ranks sum test, Mann-Whitney-U test and chi-square test as applicable.
Results : Of the fifty-five patients enrolled in the study (age range of 18-60 yrs, median age of 35yrs), 26 were males and twenty nine were females. They had a median duration of symptoms for 4 weeks. Twenty-seven patients received itopride and 28 received domperidone. One patient did not follow up in the domperidone group, thus 54 patients were evaluable for analysis. Moderate to complete symptomatic relief was observed in 22 (81%) patients in the itopride group and 19 patients (70%) in the domperidone group (p > 0.05, NS). Both the drugs were well tolerated and neither caused prolongation of QT interval nor any abnormality in any serum biochemistry values.
Conclusion : Therapy with itopride resulted in good symptomatic relief, was safe, well tolerated and comparable in efficacy to domperidone in relieving the symptoms of NUD. By virtue of its efficacy and tolerability, it could be an ideal choice for providing symptomatic relief to patients suffering from non-ulcer dyspepsia.
A STUDY ON CLINICAL PROFILE OF THE PATIENTS WITH CONGESTIVE HEART FAILURE
Authors: Prasad Dharmendra , Kumar Mahendra , Deepak Raj Kumar , Kumar Sumit , Jana Debarshi
Published: December 2020

Background: Heart failure (HF) is a common cardiovascular condition whose prevalence and incidence is increasing in the recentpast. Multiple risk factors involved in its genesis makes it more complex in the prevention and management.
Objective: The present study aimed to assess the clinical profile of the patients suffering with heart failure.
Methods: Prospective observational study was undertaken among the patients admitted in the Medical unit of Govt. Medical College and Hospital, Bettiah during October 2018 and September 2019. Patients fulfilling EuropeanSociety of Cardiology (ESC) criteria of HF were included in the study. Prevalence of congestive HF was estimated based on
community study and hospital OPD.
Results: Smoking, alcoholism, ischemic heart disease and hypertension were the leading risk factors in developing HF. Breathlessness(100%), swelling of the feet (92.3%), cough (57.7%) and palpitation (50%) were the most common symptoms observed inthe patients. Oedema feet (100%), basal crepitations (80.3%), raised Jugular Venous Distention (JVD) (57.7%) and S3 (57.7%)were the leading signs in the patients. Chest X-ray (CXR) findings indicate that 76.9% of the patients reported with increasedCardiothoracic ratio. Arrhythmias (predominantly AF-19.2%) and Left Ventricular Hypertrophy (LVH) accounted for 26.9% each.
The prevalence of HF was estimated to be in between 0.51 to 27.27 respectively.
BENIGN PROLIFERATING PILAR TUMOUR OF THE ELBOW – A RARE CASE REPORT
Authors: Paramasivam Jai Durairaj , Mahipathy Surya Rao Rao Venkata , Vaitheeswaran Shanthini , Murthy Sudharshan Srinivasa , Parthasarathy Jayaganesh
Published: December 2020

Benign proliferating pilar tumour also known as proliferating trichilemmal cyst is a rare tumor usually occurring on the head and neck region of elderly women and its pathognomonic feature is trichilemmal keratinization. Here, a 65 year old elderly female presented to us with a benign proliferating pilar tumour of the right elbow for the past 6 months for which wide local excision and a local flap was used to cover the post excisional defect. This should be differentiated from trichilemmal cyst as it has potential for malignant transformation. Thus, complete excision is recommended for all benign proliferating variants owing to their potential for locally aggressive behavior and malignant transformation.
Federated Learning using Distributed Messaging with Entitlements for Anonymous Computation and Secure Delivery of Model
Authors: Behera Monik Raj , upadhyay sudhir , Otter Robert , Shetty Suresh
Published: December 2020

Federated learning has become one of the most recent and widely researched areas of machine learning. Several machine-learning frameworks, such as Tensorflow Federated and PySyft and others have gained momentum in recent past and continue to evolve. Some of the frameworks involve techniques such as differential privacy, secure multi-party computation, gradient descent calculation over the network to achieve privacy of underlying data in federated learning. While these frameworks serve the need for a general-purpose federated learning model as per certain framework, in this paper we present a solution based on distributed messaging with appropriate entitlements that enterprises can leverage in a managed and permissioned network. The solution implements access controls on message source and destination in a decentralized network, which can implement any given data science model in the federated network to facilitate secure federated learning.
Parallel Taxonomy Discovery
Authors: Shah Shalin
Published: December 2020

Recommender systems aim to personalize the shopping experience of a user by suggesting related products, or products that are found to be in the general interests of the user. The information available for users and products is heterogenous, and many systems use one or some of the information. The information available include the user's interactions history with the products and categories, textual information of the products, a hierarchical classification of the products into a taxonomy, user interests based on a questionnaire, the demographics of a user, inferred interests based on product reviews given by a user, interests based on the physical location of a user and so on. Taxonomy discovery for personalized recommendation is work published in 2014 which uses the first three information sources { the user's interaction history, textual information of the products and optionally, an existing taxonomy of the products. In this paper, we describe a parallel implementation of this approach on Apache Spark and discuss the modifications to the algorithm in order to scale it to several hundreds of thousands of users with a large inventory of products at Target corporation. We run experiments on a sample of users and provide results including some sample recommendations generated by our parallel algorithm.
Uji Penetrasi Fitosom Ekstrak Etanol Daun Sembung Serta Uji Aktivitas Antioksidan Dengan Metode DPPH
Authors: Ikra Nurohman , Esti Mumpui , Rachmat Rachmaniar
Published: December 2020

Fitosom merupakan suatu sistem penghantaran yang dibentuk oleh bahan aktif alami dan fosfatidilkolin. Fitosom digunakan untuk meningkatkan bioavailabilitas bahan aktif. Komponen aktif dengan polaritas terlalu tinggi tidak dapat melewati penghalang lipid (lipid barrier) pada kulit atau sistem pencernaan, sehingga tidak dapat diserap. Flavonoid dalam daun sembung memiliki potensial terapetik yang luas, salah satunya adalah sebagai antioksidan, senyawa fenolik yang ada dalam flavonoid memiliki polaritas yang tinggi sehingga menyebabkan Bioavailabilitas rendah. Penelitian ini bertujuan untuk membuat fitosom ekstrak etanol daun sembung (Blumea balsamifera (L) DC.) yang memiliki penetrasi dan  aktivitas antioksidan yang lebih baik dari ekstrak etanol daun sembung. Hasil dari penelitian ini didapatkan  ekstrak etanol 70% daun sembung (Blumea balsamifera (L) DC.) dapat di buat menjadi Fitosom dengan perbandingan 1:1 antara ekstrak dan soy lechitin sebagai fosfatidilkolin menggunakan metode liofilisasi (Freeze drying). Penetrasi dari fitosom Ekstrak etanol 70% daun sembung meningkat dengan melihat kadar flavonoid total. Bentuk fitosom memiliki nilai kadar rata-rata lebih tinggi yaitu 5,03 ± 1,64 µg/g dibanding bentuk ekstrak yaitu 2,56 ± 1,23 µg/g. Aktivitas antioksidan dari ekstrak etanol 70% daun sembung (Blumea balsamifera (L) DC.) lebih tinggi dengan nilai IC50 53,01 µg/mL dibandingkan fitosom ekstrak etanol 70% daun sembung dengan nilai    IC50 78,05 µg/mL
Faktor-Faktor Penunjang Terkendalinya Kadar Hemoglobin Target Pada Pasien Hemodialisia Dengan Terapi Erytropoietin
Authors: Nurhasanah Nurhasanah , Utami Hesty
Published: December 2020

Salah satu komplikasi yang sering terjadi pada pasien Penyakit Ginjal Kronik (PGK) adalah anemia. Salah satu parameter yang biasa diperiksa pada pasien PGK yang sedang menjalani hemodialisis adalah kadar hemoglobin (Hb). Tujuan dalam penelitian ini adalah melihat hubungan antara usia, jenis kelamin, lama menjalani hemodialisa, obat-obatan dengan kadar hemoglobin pada pasien yang menjalankan hemodialisa. Penelitian ini menggunakan studi prospektif pada pasien gagal ginjal kronik yang melakukan tindakan hemodialisa di ruang rawat jalan Rumah Sakit Usada Insani Tangerang selama tahun 2017, dengan jumlah populasi 217 orang. Instrumen penelitian berasal dari data primer hasil laboratorium pemeriksaan kadar hemoglobin setiap awal bulan atau setelah 4 minggu pemberian eritropoietin. Data sekunder menggunakan pengambilan data rekam medik dan formulir pengumpulan data pasien hemodialisa. Variabel dependen kadar hemoglobin mengambilan data dari Hb rata-rata dengan pengambilan minimal 3 titik dan independen adalah usia, jenis kelamin, lama hemodialisa dan obat-obat suplemen yang mempengaruhi produksi Hb. Kelima variabel independen ini diasumsikan mempengaruhi variabel dependen. Analisis statistik yang digunakan adalah statistik deskriptif dan uji Spearmans rho correlation. Hasil penelitian menunjukkan sig usia 0.882>0.05, sig lama hemodialisa 0.819>0.05, sig suplemen 0.24>0.05 yang mempunyai arti secara uji pengolahan data statistik yaitu tidak ada hubungan antara usia, lama hemodialisa dan suplemen, Sehingga dapat disimpulkan bahwa tidak adanya hubungan antara usia, jenis kelamin, lama menjalani hemodialisa dan suplemen yang mempengaruhi target Hemoglobin dengan nilai hemoglobin. Berdasarkan hasil penelitian di ruangan hemodialisis di RS Usada Insani Tangerang didapatkan semua pasien penyakit ginjal kronik mengalami penurunan Hb
Cronologia y Cultura en el Formativo Centroandino
Authors: Bischof Henning
Published: December 2020

Abstract/short description:

The article rethinks the problem of the chronology of early Central-Andean cultures. The period after around 1500 b.c.e. when the complex societies emerged in the Andean region, was designated as Formative. Bischof's article revises this old periodization for the Central Andean region thanks to new evidence about developments in the pre-ceramic periods.

Short description written by Michał Gilewski
Toma de decisiones laborales en la corte cuzqueña de los siglos XV y principios del XVI, según las tradiciones orales apuntadas por Juan de Betanzos
Authors: Sternfeld Gabriela
Published: December 2020

Abstract/short description:

Sternfeld's article discusses available information on Inca labor management. Using the chronicle of Juan Betanzos, Sternfeld collected and analyzed 57 examples of various activities that involve elite management, such as military campaigns, creation of economic infrastructure, tribute collection, organization of religious ceremonies and ceremonies of succession. The results of the analysis of the above-mentioned allowed her to propose a complex, 15-step based model of thedecisive aspects of Inca administration and labor management.
Algunos aspectos de la economía en Morelos, México, en el siglo XVI
Authors: Konieczna Barbara
Published: December 2020

Barbara Konieczna

Abstract/short description:

The article is a short discussion of what is known about social hierarchy in 16th century indigenous Mexican polities. It discusses what was mentioned in the Spanish accounts and also utilizes archaeological evidence to portray the Mexican elites.

Short description written by Michał Gilewski
Tindak Tutur Komisif dalam Surah Al-Baqarah dan Implementasinya sebagai Bahan Teks Ceramah Siswa SMA Kelas XI (Commission Speech Act in the Surah Al-Baqarah and It's Implementation as Speech Text Materials of Class XI High School Students)

Authors: Kurniasih Dwi , Ulfiana Elita
Published: December 2020

Sebagai kalamullah Al-Qurâ€˜an memiliki pengertian yang tak terbatas. Pemahaman tersebut dapat ditelisik melalui banyak disiplin ilmu serta banyak fenomena yang ditemukan di masyarakat. Penelitian ini bertujuan mendeskripsikan bentuk serta fungsi tindak tutur komisif pada Surah Al-Baqarah dan implementasinya sebagai bahan pembuatan teks ceramah SMA kelas XI. Metode yangdigunakan adalah deskriptif kualitatif dengan pendekatan pragmatik. Data penelitian diperoleh dari Surah Al-Baqarah. Hasil penelitian menunjukkan terdapat tindak tutur komisif pada Surah Al-Baqarah yang meliputi tindak tutur komisif berniat, menjamin, menawarkan, dan berikrar/berjanji yang memiliki fungsinya masing-masing. Selain itu, tindak tutur komisif pada Surah Al-Baqarah dapat diimplementasikan di dunia pendidikan dengan menggunakannya sebagai bahan pembuatan teks ceramah siswa SMA kelas XI.As kalamullah the Qur'an has unlimited understanding. This understanding can be examined through various scientific disciplines as well as a number of events that develop in the social context of society. The purpose of this study is to describe the form and function of commissive speech acts in the Surah Al-Baqarah and its implementation as material for making class XI high school speech texts. The method used is descriptive qualitative with pragmatic approach. The research data was obtained from the Surah Al-Baqarah. The results of this study are commissive speech acts in the Surah Al-Baqarah which include, commissive speech acts threatening, intending, guaranteeing, offering, and vowing / promising that have their respective functions. In addition, commissive speech acts found in Surah Al-Baqarah can be implemented in the world of education by using them as material for making speech texts for grade XI high school students.
Pragmatik sebagai Penangkal Hoaks dan Peran Ilmuwan Bahasa di Era Digital (Pragmatics as Hoax Charm and the Role of Linguists in the Digital Era)

Authors: Wijana Prof. Dr. I Dewa Putu
Published: December 2020

Makalah ini menguraikan secara ringkas kedudukan sentral pragmatik di dalam menangkal berita bohong yang bertebaran seiring maraknya transaksi elektronik di era digital sekarang ini. Dengan mengambil contoh kasus forensik yang melibatkan berbagai tokoh penting dan orang biasa, dapat diketahui bahwa pengetahuan pragmatik yang memanfaatkan konteks ekstralingual dalam artian yang luas ternyata mampu digunakan sebagai alat yang efektif dalam mengidentifikasi dan menentukan kebenaran luar bahasa sebuah berita. Dari data-data yang terkumpul, ternyata tidak hanya masalah kebenaran luar bahasa yang disangkutkan, tetapi juga masalah-masalah internal bahasa. Sehubungan dengan hal itu, pengetahuan tentang aspek-aspek internal bahasa yang dipelajari cabang ilmu-ilmu bahasa lain juga sangat bermanfaat di dalam menerangkan aspek-aspek internal bahasa. Di samping itu, masalah-masalah internal ini juga sering menjadi permasalahan utama dalam kasus-kasus forensik, baik di media elektronik maupun saluran komunikasi lain. Kenyataan ini semakin mengokohkan sentralnya peran ahli bahasa di masa depan.Â This article will briefly describe the central role of pragmatics in avoiding hoaxes which are recently scattered in line with the glow of electronic transactions in the digital era. By taking examples from several forensic cases which involve public figures and ordinary citizens, it can be concluded that the knowledge of pragmatics which exploits extralinguistic contexts in its broadest sense can be used as an effective tool in identifying and determining the extralinguistic truths of a news. The data collection shows that the utterances sometimes contain internal linguistic aspects. Accordingly, the knowledge about internal aspects of a language which constitute objects studied by other linguistic branches, are also fruitful for explaining these internal aspects. Besides, the internal aspects are also possible to be the main problems of in forensic cases which are either delivered through electronic medium or other communication channels. All these matters strongly confirm the central role of linguists in the nearly future. Â
Investigation into the control strategy for a long spine of Edinburgh Duck modules, using an efficient numerical model
Authors: Cotten Alfred , Forehand David I. M.
Published: December 2020

An efficient numerical model of a spine of ten Edinburgh duck modules is developed. The spine joints and duck modules are modelled using a linear approach based on the theory of generalized modes, which mitigates the need for a more computationally expensive time- domain solver. This approach also allows for computation of the shear forces acting on the spine joints, and has the added benefit of enabling the use of complex conjugate control. The resulting hydrodynamic model is verified for a three duck spine against an alternative implementation that uses a nonlinear multibody solver to enforce the joint motions. A conservative weighted motion constraint is imposed on the controlled degrees of freedom of the ten duck spine, in order to ensure results stay within the bounds of the linear theory. Pertinent sections of the theory underpinning the constrained complex conjugate control method are elaborated upon for the case in which not all degrees of freedom are controlled. An implementation of this control method for a solo duck is compared against a result from the literature, in order to confirm the suitability of the choice of duck design in this study. The control force coefficients that maximise the absorbed power, subject to the motion constraint, are computed for the ten duck spine over a range of wave periods and wave heading angles. The resulting dynamics of the spine of ducks are explored, with particular emphasis on aspects related to the power extraction and forces acting within the system.
PERFIL CLÍNICO E EPIDEMIOLOGICO DE PACIENTES QUEIMADOS
COM INFECÇÃO NOSOCOMIAL
Authors: Ferreira Tereza Cristina dos Reis , Torres Luciano Gil Saldanha , Monteiro Brenda Beatriz Silva , Lima Paula Thayna Soares , Santos Emmanuelle Priscilla Gurjão Vieira , Tostes Libia Ferreira , Gomes Henrique da Silva , Chaves Bruna Melo , Falcão Lee Bezerra
Published: December 2020

Este estudo teve como objetivo analisar o perfil clínico e epidemiológico dos pacientes queimados do Centro de Tratamento de Queimados do Hospital Metropolitano de Urgência e Emergência (HMUE) com infecção nosocomial. Foram analisados 175 prontuários de pacientes com perfil clínico e epidemiológico vítimas de queimaduras apresentando infecção nosocomial no HMUE no período de Março de 2006 a Junho de 2012. Neste presente estudo obteve-se que o sexo masculino (70,85%) é o mais acometido por acidentes com queimaduras. Quanto à idade foi mais prevalente na faixa etária entre 18 anos em diante (49, 14%), tendo como principal agente etiológico Pseudomonas aeruginosa (57,14%), e o principal local de queimadura foi em tórax (23,4%). O grau de queimadura de maior índice foi de 2° grau em (44,77%), a extensão da queimadura foi em médio porte (45,14%). O tempo de internação variou-se acima de 31 dias (48, 57%) com tempo em média de 33 dias, sendo o tempo de infecção entre 21 a 30 dias (30, 28%) com tempo em média de 24 dias, e a condição de alta hospitalar sendo melhora do paciente (72,57%). A fisioterapia atua com objetivo de prevenir ou minimizar essas complicações, porém novos estudos deverão ser realizados para ressaltar a importância da fisioterapia respiratória e motora em pacientes com queimaduras.
Józef Elsner. Utwory fortepianowe / Piano Works, wyd. / ed. Jerzy Morawski, Warszawa 2016 (= Monumenta Musicae in Polonia, seria/ series E: Opera selecta)
Authors: Poniatowska Irena
Published: December 2020

Recenzja edycji nutowej: Józef Elsner. Utwory fortepianowe / Piano Works, wyd. / ed. Jerzy Morawski, Warszawa 2016 (= Monumenta Musicae in Polonia, seria/ series E: Opera selecta)