bluuebunny/crossref_metadata_2025 huggingface dataset:
The Influence of Perceived Social Presence on the Willingness to Communicate in Mobile Medical Consultations: Experimental Study
Authors: Chen Lijuan , Zhang Danyang , Hou Mutian
Published: May 2022

Background

With the rise of online health care service, there is growing discussion on the relationship between physicians and patients online, yet few researchers have paid attention to patients’ perception of social presence, especially its influence on their willingness to communicate (WTC).

Objective

The goal of the research is to investigate the influence of perceived social presence (PSP) on WTC in mobile medical consultations.

Methods

Participants living in Yunnan province during the period of middle to high risk of COVID-19 infection were recruited via the internet. They were assigned randomly into 2 groups interacting with a virtual physician presenting high and low levels of social presence and then asked to complete a questionnaire. Based on the theoretical framework, the study puts forward a model evaluating the relationships among participants’ PSP, communication apprehension (CA), self-perceived communication competence (SPCC), and willingness to communicate about health (WTCH) in the computer-mediated communication between virtual physicians and patients.

Results

In total 206 (106 in group 1 and 100 in group 2) valid samples were gathered (from 276 log-ins) and 88.8% (183/206) of them were aged 18 to 44 years, which approximately resembles the age distribution of the main population engaging in online medical consultation in China. Independent t test shows that there is significant difference between the PSP of the 2 groups (P=.04), indicating a successful manipulation of social presence. The total effect of PSP on WTCH is 0.56 (P<.001), among which 74.4% is direct effect (P<.001). Among the indirect effects between PSP and WTCH, the mediating effect of SPCC accounts for 68.8% (P<.001) and the sequential mediating effect of CA→SPCC accounts for 19.2% (P<.001), while the mediating effect of CA alone is not significant (P=.08).

Conclusions

This study provides a comprehensible model, demonstrating that PSP is an important antecedent of WTCH, and the sequential mediating effect of CA and SPCC found in this study also proves that in the environment of online mobile medical services, CA cannot affect communication directly. The findings will provide some practical inspiration for the popularization of online medical service, especially for the promotion of online physician-patient communication.
Research on Digital Technology Use in Cardiology: Bibliometric Analysis
Authors: Yeung Andy Wai Kan , Kulnik Stefan Tino , Parvanov Emil D , Fassl Anna , Eibensteiner Fabian , Völkl-Kernstock Sabine , Kletecka-Pulker Maria , Crutzen Rik , Gutenberg Johanna , Höppchen Isabel , Niebauer Josef , Smeddinck Jan David , Willschke Harald , Atanasov Atanas G
Published: May 2022

Background

Digital technology uses in cardiology have become a popular research focus in recent years. However, there has been no published bibliometric report that analyzed the corresponding academic literature in order to derive key publishing trends and characteristics of this scientific area.

Objective

We used a bibliometric approach to identify and analyze the academic literature on digital technology uses in cardiology, and to unveil popular research topics, key authors, institutions, countries, and journals. We further captured the cardiovascular conditions and diagnostic tools most commonly investigated within this field.

Methods

The Web of Science electronic database was queried to identify relevant papers on digital technology uses in cardiology. Publication and citation data were acquired directly from the database. Complete bibliographic data were exported to VOSviewer, a dedicated bibliometric software package, and related to the semantic content of titles, abstracts, and keywords. A term map was constructed for findings visualization.

Results

The analysis was based on data from 12,529 papers. Of the top 5 most productive institutions, 4 were based in the United States. The United States was the most productive country (4224/12,529, 33.7%), followed by United Kingdom (1136/12,529, 9.1%), Germany (1067/12,529, 8.5%), China (682/12,529, 5.4%), and Italy (622/12,529, 5.0%). Cardiovascular diseases that had been frequently investigated included hypertension (152/12,529, 1.2%), atrial fibrillation (122/12,529, 1.0%), atherosclerosis (116/12,529, 0.9%), heart failure (106/12,529, 0.8%), and arterial stiffness (80/12,529, 0.6%). Recurring modalities were electrocardiography (170/12,529, 1.4%), angiography (127/12,529, 1.0%), echocardiography (127/12,529, 1.0%), digital subtraction angiography (111/12,529, 0.9%), and photoplethysmography (80/12,529, 0.6%). For a literature subset on smartphone apps and wearable devices, the Journal of Medical Internet Research (20/632, 3.2%) and other JMIR portfolio journals (51/632, 8.0%) were the major publishing venues.

Conclusions

Digital technology uses in cardiology target physicians, patients, and the general public. Their functions range from assisting diagnosis, recording cardiovascular parameters, and patient education, to teaching laypersons about cardiopulmonary resuscitation. This field already has had a great impact in health care, and we anticipate continued growth.
Legal Aspects Related to the Termination of the Kumanovo Agreement (1999) and Possibilities for Serbian Armed Forces to return to Kosovo in Case of Termination of that Agreemen
Authors: Janev Igor
Published: May 2022

This article examines the Kumanovo Agreement as an obstacle to possible Serbian military intervention in Kosovo and Metohija (hereinafter shortly: Kosovo) in case of uncontrolled Albanian invasion against the Serb population in Kosovo. The Military Technical Agreement between the International Security Force (“KFOR”) and the Governments of the Federal Republic of Yugoslavia and the Republic of Serbia, known as the Kumanovo Agreement, represents a legal limitation to any involvement of the Serbian military force(s). With respect to the Kumanovo Agreement the consent element required for such peacekeeping agreements appears to be missing. The absence of consent element of the agreement undermines the legal basis and thus the legal validity of the Kumanovo treaty reached under apparent coercion in 1999. It appears that Kumanovo Agreement in the absence of proper consent requirement may be interpreted as a dubious act under the Vienna Convention on the Law of Treaties (hereinafter VCLT), particularly Article 52 (related to the Coercion of a State by the threat or use of force). Therefore, the Kumanovo Agreement, as an Annex to the Security resolution 1244 (1999), can be considered as an invalid act according to the VLCT. As a consequence of its invalidity, the Serbian government in warlike situations, in case of massive human rights violations by Kosovo authorities against Serbian population, may resort to termination of the Kumanovo Agreement (under Article 52 and even under Article 53 (jus cogens) of the VLCT) for aim to protect the Serbian population against ethnic cleansing, oppression and other human rights violations of International (humanitarian) public Law.
APPLICATION OF NANOANTIBIOTICS APPROACH AGAINST ANTI-BACTERIAL RESISTANCE
Authors: MAHMOOD ALABDALI AYA YASEEN , KZAR MARWAH SAMI , CHINNAPPAN SASIKALA , RAM MANI RAVISHANKAR , SELVARAJA MALARVILI , WEN KOK JING , SALLY LAI , KUANG FU WAI
Published: May 2022

Despite the fact that we live in an era with unique and advanced technology for revealing underlying molecularly creating new drugs and disease mechanisms, infectious illnesses remain one of the world's major health issues. Antimicrobial agents now available against pathogenic microorganisms are insufficient to combat the problems posed by novel multidrug-resistant (MDR) infections. Antimicrobial drug restrictions are producing negative side effects and the development of multiple drug resistance. Drug resistance will necessitate the use of high-dose antibiotics, resulting in severe toxicity and the development of new medicines. Nanoantibiotics, a new type of antimicrobial agent that combines antimicrobial compounds with nanoparticles, has been created to solve these shortcomings. Additionally, previous reports stated that the pharmacokinetics profiles and have quicker ingestion in circulatory framework. In this subject, we will clarify the various sorts of nanoantibiotics, their instrument of activity, key targets and medication discharge components. We will likewise portray some significant microbial elements that will influence the activity of nanoantibiotics.
VALIDATED SPECTROPHOTOMETRIC METHODS BASED ON CHARGE TRANSFER COMPLEXATION REACTION FOR THE DETERMINATION OF VALACYCLOVIR HYDROCHLORIDE AS ANTIVIRAL DRUG IN PHARMACEUTICAL FORMULATIONS
Authors: AMIN ALI H. , EL SHEIKH RAGAA , YOUSSEF AHMED O. , ABDEL FATTAH GHADA M. , GOUDA AYMAN A.
Published: May 2022

Objective: The present study aims to develop and validate two simple, sensitive, accurate, precise and economical spectrophotometric methods for the determination of valacyclovir HCl (VAL) in pure form and pharmaceutical formulations.
Methods: The developed methods are based on the formation of charge-transfer complex between VAL as n-electron donor and quinalizarin (Quinz) or alizarin red S (ARS) as π-acceptor in methanol to form highly colored chromogens, which showed an absorption maximum at 565 and 540 nm using Quinz and ARS, respectively. The optimization of the reaction conditions such as the type of solvent, reagent concentration and reaction time were investigated.
Results: Under the optimum conditions, Beer’s law is obeyed in the concentration ranges 0.5–16 and 1.0–20 μg/ml using Quinz and ARS, respectively, with good correlation coefficient (r2 ≥ 0.9994) and with a relative standard deviation (RSD% ≤ 0.70). The limits of detection and quantification were found to be 0.15 and 0.30 µg/ml for Quinz and 0.50 and 1.0 µg/ml for ARS.
Conclusion: The methods were successfully applied to the determination of VAL in its pharmaceutical formulations and the validity assesses by applying the standard addition technique. Results obtained by the proposed methods for the pure VAL and commercial tablets agreed well with those obtained by the reported method.
Experimental Investigation of Flexible Pavement Using Shingles
Authors: Joshi Bhavika , Kanake Nikhil , Koli Rahul , Tambare ajanan , Kumar Mithun
Published: May 2022

Abstract: Huge volumes of Shingles are produced from building construction and Asbestos industries. Basically, waste Shingles Aggregates (WSA) are being produced by crushing Shingles during the process of transport and installation of roof, wall and floor. Present society are progressively moving forward to be more environment friendly. To meet up this purposes, recycling and reuse of this material can be the best alternatives than landfill disposal in respect of environment conservation and economy. To increase the usage of Shingles in pavement construction, different percentage of Shingles can be used with the natural aggregate. The technical flexibility of using waste Shingles aggregates as partial replacement of natural aggregates in bituminous mixes can be evaluated. This research work presents some of the laboratory investigation on the possible application of waste Shingles aggregates in bituminous mixes. The physical properties of coarse aggregates, fine aggregates, filler and bitumen are determined according to standard test. Marshall test specimens are prepared for testing to measure the Marshall properties. at optimum bitumen respectively are determined. According to AASHTO, Marshall stability test properties of mixes of waste shingles aggregates are satisfactory. investigated results indicate that the bituminous mixes with waste shingles aggregates give satisfactory results for construction of medium traffic road Keywords: Waste Shingles Aggregates, Marshall Mix Design, Flexible Pavement Construction
Experimental Study on Concrete Mix Design by replacing Fine aggregate by Crushed tiles & Cement With marble powder
Authors: Pakhare Diksha , Pandhare Sanjana , Parad Siddhi , Tanganath Krishnaveni
Published: May 2022

Abstract: Concrete is one of the oldest manufactured construction material used constructions of various structures around the world. Due to its high demand the material used for concrete production depleting every year. Thus, around the world new construction materials are being investigated. In this study ceramic waste was used as replacement of fine aggregate and marble waste used as replacement of cement. The scope of the study includes the investigation on the compressive strength. The method of study to be carried out is through the appropriate test on aggregate, sand, cement, marble slurry and ceramic powder. The entire tests have been carried out and the results had been recorded and analysed in appropriate table. Keywords: Marble slurry, Concrete, Ceramic waste, Cement, Compressive strength.
Meeting the Challenges of Safety Management in Wind Energy Industry
Authors: Dhiravidamani Dr. P. , Vigneshvaran R.
Published: May 2022

Abstract: Countries promoting renewable energies encounter a variety of phenomena that can challenge the implementation of further onshore wind energy development. Those challenges can be observed in many multi-level governance systems, as exhibited in the U.S., Germany, and Mexico, where various regulatory and institutional levels must agree on goals and responsibilities. (1) Political and market phenomena, (2) siting issues, (3) the green vs. green dilemma, and (4) social acceptance are selected challenges within the different levels of decision-making processes in wind energy implementation. In this paper these challenges can enhance outlooks in policy and planning, posing solutions to wind energy challenges even in sensitive environments and triggering innovations such as adaptive management. Keywords: Governance, Renewable Energies, Wind Energy, Triggering.4
Efecto tóxico y antidiabético de tres plantas amazónicas en ratones balb/c inducidas con estreptozotocina
Authors: Peña Hidalgo Marx , Espinoza Campos Freddy Orlando , Donayre Ramirez Marjorie , Villacrés-Vallejo Jorge , Vásquez Torres Diego
Published: May 2022

La diabetes mellitus tipo 2 tiene gran impacto en las poblaciones a nivel mundial, las medicinas utilizadas para tratar esta patología tienen elevado costo y efectos adversos, actualmente se conocen diferentes terapias con vegetales; por lo tanto, realizar estudios con plantas medicinales como antidiabéticos son relevantes debido a su fácil preparación, mínimo costo, bajo o ningún efecto adverso. El estudio evaluó el efecto tóxico y antidiabético de Myrciaria dubia, (camu camu), Coussapoa asperifolia (renaco caspi) y Ciliosemina pedunculata, (chullachaqui caspi) en ratones balb/c inducidas con estreptozotocina (STZ). Para ello, se realizó ensayo de toxicidad aguda a 2000 mg/kg y efecto antidiabético a 100, 500 y 1000 mg/ kg. Los resultados mostraron que los tres extractos acuosos de las especies no tienen efectos tóxicos, pero tienen efecto antidiabético. El análisis muestra que los vegetales estudiados presentan metabolitos secundarios que son responsables del efecto antidiabético, al mismo tiempo, ello no tiene efecto tóxico contra los ratones. En conclusión, todos los extractos de dichas plantas son inocuos; por lo tanto, es seguro consumirlas. Además, de todos los extractos tiene efecto antidiabético excepto Coussapoa asperifolia a dosis de 100 mg/kg.
Analisis Kelayakan Desain Air Purifier pada Ruangan Tertutup Berbasis Internet of Things
Authors: Amiroh Khodijah , Widyantara Helmy , Permata Oktavia Ayu
Published: May 2022

Kesehatan lingkungan perlu menjadi perhatian utama seperti polusi udara yang mengakibatkan pencemaran lingkungan. Saat ini, 90% orang beraktifitas pada ruangan tertutup. Banyaknya aktifitas seseorang dalam ruangan menjadikan kebersihan udara pada ruangan suatu hal yang penting karna berdampak langsung pada kesehatan manusia. Beberapa indikator penting antara lain kadar debu, kadar ethanol, gas CO, dan kelembaban udara. Penelitian dilakukan dengan beberapa tahap mulai dari perancangan sistem, implementasi sistem, hingga melakukan analisis kelayakan sistem. Perancangan sistem dilakukan dengan membuat desain air purifier yang lebih ergonomis yang terdiri atas karbon, hepa filter, UV serta exhaust berbasis IoT. Design air purifier dan sistem kontrol otomatis yang dibuat diperlukan sebuah analisis kelayakan untuk mengetahui seberapa efektif prototipe yang telah dibuat. Sistem monitoring berbasis IoT dibuat dengan menggunakan Arduino ESP32 dan DHT 22 dengan menggunakan aplikasi mobile sebagai sistem monitoring. Implementasi sistem dilakukan dengan mencari bahan yang dapat dimanfaatkan dalam perancangan sistem dan dapat melindungi pancaran radiasi sinar uv tidak membahayakan lingkungan sekitar. Hasil dari uji kelayakan dilakukan terhadap air purifier pada laboratorium dinas provinsi jawa timur dengan menggunakan indikator gas CO, kadar debu, dan kadar etahanol di dalam udara. Hasil dari pengujian tersebut diketahui bahwa hasil perancangan air purifier dapat melakukan penurunan kadar CO hingga >82% dalam jangka waktu 15 menit. Kadar debu di udara mengalami penurunan hingga 63,81% dalam jangka waktu 50 menit serta penurunan kadar ethanol dalam udara sebesar 93,52%.
Komparasi Pengelompokan Pemeringkatan Sertifikasi Travel Umrah Berizin dengan Algoritma Klasterisasi K-Means dan K-Medoids
Authors: Risky Muhammad , Wibowo Arief , Anshori Zakaria
Published: May 2022

Dengan Terbitnya Undang-Undang Nomor 11 Tahun 2020 tentang Cipta Kerja yang merevisi beberapa pasal dalam Undang-Undang Nomor 8 Tahun 2019 tentang Penyelenggaraan Haji dan Umrah, Kementerian Agama harus melakukan pembahasan tentang peraturan turunankedua Undang-Undang tersebut. Di antara peraturan turunan yang diterbitkan adalah Keputusan Menteri Agama (KMA) Nomor 1251 Tahun 2021 tentang Skema dan Kriteria Akreditasi serta Sertifikasi Usaha Penyelenggaraan Ibadah Umrah dan Penyelenggaraan Haji Khusus. Dalam KMA ini, Kementerian Agama melaksanakan pengaturan berkenaan dengan pemeringkatan PPIU dan juga PIHK, yang dibagi pemeringkatan menjadi 3 kelompok yaitu A, B C. Penelitian ini bertujuan untuk menganalisa dengan pembanding atau referensi lain menggunakan metode penambangan (mining). Penambangan (mining) yang dipergunakan pada penelitian ini adalah terhadap data. Dataset akan di proses dengan algoritma yang ditemukan oleh Lloyd dan kawan-kawan, yakni K-Means. Selain itu, dataset juga akan diproses dengan salah satu algoritma lain untuk pengelompokan data, dalam hal ini peneliti memilih K-Medoids. Dataset terdiri dari 5.000 baris data sesuasi dengan penilaian indikator dominan dan ko-dominan. Hasil Penelitian menunjukkan bahwa metode K-Means dengan dua kelompok dengan maksimize tanpa normalize memiliki Davies-Bouldin Index (DBI) 0,234. Sedangkan metode K-Means dengan 2 kelompok serta melakukan normalize maka Davies-Bouldin Index (DBI) adalah 0,005. K-Means adalah yang paling optimal dibanding K-Medoids pada penelitian ini.
La escritura académica. Un reto para la formación posgradual primer aporte
Authors: Arbeláez Gómez Martha Cecilia , Garzón Osorio Martha Lucía , Henao García Luz Stella , Puerta Giraldo Carlos Emilio , Salazar Marín Tatiana , Gutiérrez Valencia Karolaim , Guerra Narváez Daniel Mauricio
Published: May 2022

La escritura, aquella tarea aparentemente fácil, tiende a complicar la vida académica de expertos y novatos. Aunque se cree aprendida desde el colegio, cuando nos enfrenta a la composición de un texto académico nos desanima, nos asusta y a veces nos conduce a la autoexclusión. Así, aquella competencia que se daba por desarrollada en el pregrado, pues ya se escribieron muchos ensayos, resúmenes, explicaciones, cuando llegamos al posgrado vuelve a angustiarnos, y a veces a paralizarnos. El libro parte precisamente de esta pregunta ¿Cómo se transforma la escritura académica durante el proceso de formación posgradual? Responder esta pregunta implicó para los autores adentrarse en los textos escritos de los estudiantes desde su ingreso hasta la culminación de la formación, para dejar en evidencia las transformaciones, pero también la persistencia en múltiples dificultades que no logran superarse en dos años de formación. También puso en cuestión el papel de la escritura durante los diversos seminarios orientados, el papel del asesor del proyecto de grado y alertó sobre la necesidad explícita de trabajar la escritura como un eje importante de formación.
ON DEGREE BASED TOPOLOGICAL INDICES OF SELF-ASSEMBLED TETRAPHENYLETHYLENE AND TERPYRIDINE ROSETTES
Authors: RENAI P NOAH ANTONY , Santiago Roy
Published: May 2022

A technique is described to compute topological indices for
supramolucular rosettes of tetraphenylethylene (TPE) and terpyridine
(TPY) ligands with its applications on physicochemical and biological
properties. This technique, we have applied to a self assembled TPE and
TPY supramolucular graphs which is obtained in the form of rosette
cycles. Also these type of rosettes graph finds significant applications
in electrical sensors, light emitting diodes, bioimaging and
photoelectric devices etc. As regarded to the next generation sensing
applications with a typical induced aggregative emission behaviour,
tetraphenylethylene can be utilised in constructing fluorescent probes.
For this supramolucular systems we have done a work by computing some
topological indices such as the variants of Zagreb index, Randić
index, Sum Connectivity index, ABC index and Harmonic index.
Use of polysaccharide hemostatic agent (HaemoCerTM) in breast cancer surgery to reduce postoperative complications: a randomized controlled trial
Authors: Falcone Veronica , Krotka Pavla , Deutschmann Christine , Danziger Sabine , Reischer Theresa , Pfeiler Georg , Singer Christian , Koch Marianne
Published: May 2022

Objective: To evaluate whether the application of polysaccharide
hemostatic agent during breast conservative surgery affects the
perioperative period. Design: Randomized, masked, single-center study
Setting: Breast-care unit, at the Medical University of Vienna
Population: Pre- and postmenopausal women affected by intraductal or
invasive breast cancer, undergoing breast conservative surgery. Methods:
Women were randomly assigned polysaccharide hemostatic agent or not,
intraoperatively. Main outcome measures: Primary outcome was the total
volume of postoperative drained fluid from the surgical site. Secondary
outcomes were number of days until drain removal, rate of immediate
postoperative surgical site infection, and total volume of postoperative
drained fluid from the surgical site. Results: Patients in the
intervention group had significantly higher drainage output volumes
compared to the control group 85ml (IQR 46.25-110) vs. 50ml (IQR 30-75),
respectively; (p=0.003). A univariable linear regression analyses,
showed a significant association between the surgical specimen and the
primary outcome (p<0.001). After multivariable analysis, the
use of absorbable polysaccharide hemostatic product was no longer
significantly associated with a higher drainage output and only the size
of the surgical specimen remained a significant predictor. The number of
days until drainage removal and the postoperative seroma formation were
higher in the intervention group, (p=0.004) and (p=0.003), respectively.
Conclusion:In our study, intraoperative application of polysaccharide
hemostatic agent during breast-conserving surgery did not decrease
postoperative fluid production.Only the size of the surgical specimen
was significantly associated with postoperative drainage volume.
Tweetable abstract:Intraoperative polysaccharide hemostatic does not
reduce the volume of postoperative fluid drained after breast
conservative surgery
Obstructed labor and associated factors among laboring women, Northeast Ethiopia.
Authors: Adamu Kidist , Fentaw Zinabu
Published: May 2022

Introduction: Obstructed labor is still the major cause of maternal
morbidity and mortality, and adverse birth outcomes in low-income
countries. This study aims to assess obstructed labour and associated
factors among laboring women in Northeast Ethiopia. Methods: A
retrospective cross-sectional study was conducted among 183 labouring
mothers at Mekane Selam Primary Hospital in Northeast, Ethiopia. A
random sampling method was employed to recruit a sampled chart from
labour and delivery register through lottery methods. The adjusted odds
ratio with a 95% confidence interval was used to calculate the strength
of the association between obstructed labour and independent predictors.
Variables with P-value less than 0.05 were considered statistically
significant in multivariable logistic regression analysis. Result: The
prevalence of obstructed labour was 14.8% [95% CI: 9.9-19.8],
which significantly associated with primiparity [AOR =14.79, 95% CI:
(1.78, 122.69)], mothers who stayed from 12-24 hours and
>24 hours before visiting hospital [ AOR =5.908, 95% CI
(1.438, 24.275)], [AOR=8.49, 95% CI:(1.045, 69.001], respectively
and mothers who got intervention in > 8 hours after arrival
in health setting [AOR=6.40, 95% CI (1.310, 31.229). Conclusion:
Obstructed labour was high among mothers who gave birth at Mekane Selam
General Hospital. Factors like time of arrival to intervention, parity,
and duration of labour before visiting the hospital (12-24 Hrs’ and
>24 hrs) were significantly associated with obstructed
labor in multivariable analysis. Government and health professionals
should emphasize system of prevention and reduction of these risk
factors.
Evaluating the impact of climate change on the distribution of rare and endangered tree Firmiana kwangsiensis using Maxent modeling
Authors: Gao Xiao-Xuan , Liu Jing , Huang Zhi-Huan
Published: May 2022

An upsurge in anthropogenic climate change has accelerated the habitat
loss and fragmentation of wild animal and plants. The rare and
endangered plants is an important elements of biodiversity, but holistic
conservation management has been hampered by lacking of detailed and
reliable information about their spatial distribution. Our aim is to
study the consequences of climate change on geographical distributions
of a rare tree species Firmiana kwangsiensis (Malvaceae) to provide
reference for conservation, introduction and cultivation of this
species. Based on 30 effective occurrence records and 27 environmental
variables, we modeling the potential distribution of F. kwangsiensis
under current and two future climate scenarios in maximum entropy. We
found that the potential suitable habitat boundary of F. kwangsiensis
were limited by precipitation-associated variables and
temperature-associated variables. Our model predicted 259,504 km2 of F.
kwangsiensis habitat based on 25 percentile thresholds in contemporary,
of which the high suitable area is about 41,027 km2. Guangxi’s protected
areas provide the most coverage for F. kwangsiensis habitat. However,
the existing reserves encompass 2.7% of the total suitable habitat and
4.2% of the high suitable habitat, which is lower than the average
protection intensity in Guangxi (7.2%), meaning protected areas network
is currently insufficient and alternative conservation mechanisms are
needed to protect the habitat. Our findings will help to identify
additional localities where F. kwangsiensis may exist, and also where it
may spread to. It provides important information for the conservation
management and cultivation of such rare tree species.
Geoelectrical Assessment of Aquifer Potentials and its Vulnerability to Contaminant at El - Amin Proposed University Site, Minna, Niger State, Nigeria
Authors: J Shehu
Published: May 2022

Vertical Electrical Sounding (VES) survey was carried out at EL - Amin proposed University site, Located along Eastern bye pass Minna, Niger State, Nigeria. It lies in the basement complex region of Northern Nigeria. The survey was carried out with the aim of determine the ground water potentials of the area and evaluate its aquifer protective capacity. The technique employed was the Vertical Electrical Sounding (VES) using Schlumberger array. A total of 48 VES points were sounded on grid profiles separated by 100 m apart with VES spacing of 100 m. Three to four layers were observed. The Stratigraphy of subsurface shows: topsoil with resistivity range from 0.4 to 277.89 Ωm, Weathered/Fracture basement layer having resistivity vary between 31.0 and 982.89 Ωm and Fresh basement with resistivity range from 19.1 to 79935.239 Ωm. The Weathered/Fractured layer was considered as aquiferous horizon. The Longitudinal Conductance and resistivity Contour maps were produced. Thirteen VES points were delineated as groundwater potential with resistivity ranging from 45.5 Ωm to 611.77 Ωm, thickness ranging between 3.5 m and 13.07 m and depth ranging from 8.8 m to 24.43 m which represent about 18.75 percent of the area. The south, south - east and north - west portions of the area are underlain by materials of moderate to good protective capacity while the western and central part of the area with thin overburden coincided with weak to poor protective capacity which will exp ose the groundwater in the area to pollution.
Solution of the Problem of Crack Opening by Methane in the Extremely Stressed Zone of the Formation
Authors:   Federal Research Centre of Coal and Coal Chemistry of SO RAN, Cherdantsev N.V.
Published: May 2022

The conditions were studied concerning the cracks opening by in-situ methane in the formation marginal zone during its transition to the maximum stressed state. The calculations are based on the joint use of the fundamental methods of deformable solids mechanics, statics of the flowing medium, and the concept of academician S.A. Khristianovich on the distribution of pressure of intra-layer methane during the movement of the mine face at a constant speed. The stress field of a coal-rock mass containing a seam with a weak interlayer and a working through it, was constructed within the framework of an elastic-plastic problem of the stressed state of a coal-rock mass. It is reduced to the integral equation of the second external boundary value problem of elasticity theory and solved by the boundary element method. The stress distribution in the extremely stressed zone of the formation is constructed by the method of characteristics known in the theory of differential equations. In the model of the ultimate stress state of a structurally homogeneous formation, the limiting zones are formed from the edge itself. In the formation with an unstable interlayer, the interlayer passes to the limiting state first, and at some distance from the edge, the formation itself. After that, the formation and the intermediate layer are deformed as integral whole. The cracks in the formation, which are its slip lines, open when the pressure of in-situ methane exceeds the stresses normal to the contour of the slip line. These stresses are related to the values of the principal stresses found from the solution of the boundary value problem. From this condition, the dimensions of the formation edge zone with free methane surfaces are determined.
Der Schlüssel zur Stärke.Wie Teams resilient und „krisenfest“ werden
Authors: Steeger Oliver
Published: May 2022

Viele Unternehmen wollen sich nach der schwierigen Zeit der Pandemie besser gegen Krisen aufstellen. Das schließt auch die Resilienz von Mitarbeitern und Teams ein. Wissenschaftler sind sich sicher: Jeder kann die Fähigkeit lernen, bei Krisen zügig aus der Schockstarre zu kommen und handlungsfähig zu werden. Doch mit einem einzelnen Resilienz-Training ist es nicht getan. Der Aufbau von Resilienz ist kein Sprint, sondern ein Marathonlauf. Dr. Susanne Marx (CSL Behring GmbH) führt in ihrem Unternehmen seit mehr als zwei Jahren ein vielfältiges Programm für Gesundheit und Resilienz durch. Im Interview berichtet sie, wie man in Teams und Organisationen Resilienz aufbaut, welche Handlungsebenen es gibt – und weshalb Achtsamkeit der Schlüssel zur Stärke ist.
PRACTICAL ORIENTATION OF STUDENTS 'EDUCATION FROM THE POSITION OF INTEGRATION INTO THE SINGLE EDUCATIONAL EUROPEAN SPACE
Authors: Kovtyuk N. , Godovanets O.
Published: May 2022

Today, our country is actively integrating into the single European educational space, which consists in reforming and modernizing higher education through modern technologies of reorganization of the educational process, which results in improving the quality of education. Integration processes are ambiguous, have many different problems, the most important of which is the problem of unification of national cultures and national education systems, loss of national identity and loss of educational, cultural, national and ethnic diversity of the world. Training future doctors at the level of international standards is one of the most important strategic tasks of higher education in Ukraine.The teaching methodology involves a model of educational and professional activities designed by the teacher, which is implemented as a set of specific techniques, actions and operations. The method of teaching from the standpoint of teaching pediatric disciplines is a way of joint activities of a doctor-teacher and a student, aimed at achieving the goals and values that determine the formation of the future doctor's personality and mastering the basics of professional activity. Accordingly, there is a need to help improve the quality of practical knowledge and skills of future professionals. No matter how useful remote technologies are, the methods of the classical domestic medical school were and remain the main ones at the clinical department. Studying at the patient's bedside allows the student to better feel the atmosphere of the future profession. Analysis and evaluation of achievements is carried out with the help of pedagogical control and self-control, which allows to accurately identify the level and quality of knowledge, skills and abilities acquired by students, the degree of formation of educational activities and "internal" increments learning and under its influence understanding of oneself, one's changes. It is extremely important that students understand the functions of pedagogical control, so that they can cooperate with teachers and contribute to the improvement of the educational process. The quality of medical student training is the main indicator of the effectiveness of the department, faculty and the university in general. This directly affects the rating of a medical university, as well as the system of medical education in Ukraine.
MATERNAL STRESS ASSESSMENT IN THE NEONATAL INTENSIVE CARE UNIT
Authors: Pavlyshyn H. , Sarapuk I. , Saturska U. , Skubenko N. , Zaitseva T.
Published: May 2022

Introduction. The birth of preterm infants who require treatment in the neonatal intensive care unit (NICU) can be very stressful for parents.The aim of the study was to assess the level of stress in mothers of preterm newborns in the NICU, and to determine the factors that induce it.Material and Methods. The study included a maternal stress assessment of 141 mothers of preterm infants, treated in the NICUs, using the Parental Stress Scale: PSS: NICU. This questionnaire consisted of three subscales: Sights and Sounds of NICU – subscale 1 (S1), Infant Appearance and Behavior – S2, and Parental Role Alteration – S3.Results. Total PSS: NICU score in mothers was 3.38±0.71. 98 (69.5%) mothers experienced high levels of stress. Parental Role Alteration was the most stressful (4.14±0.76); Infant Appearance and Behavior (3.43±0.89) and Sights and Sounds in NICU also caused stress (2.21±0.97); p(S1–S2)<0.001, p(S1–S3)<0.001, p(S2–S3)<0.001. There was an association between the level of maternal stress and the number of visits to the NICU (p = 0.047), as well as the severity of an infant health status (presence of seizures in newborns (p = 0.006) and the need for ventilation) (p = 0.041). Mothers who kept on breastfeeding their infants at the time of discharge had lower stress scores, particularly in the Parental Role Alteration subscale (p = 0.011).Conclusion. Mothers of preterm infants who require the treatment in the NICU experience significant stress, as confirmed by a standardized questionnaire, with the most intensive parental role alteration. The scores of maternal stress depend on the severity of a child's condition (duration of treatment, presence of seizures, the need for ventilation), and the number of visits to the NICU.
A person-centred approach to COVID-19 pandemic-related stressors
Authors: Blais Ann-Renee , Blouin Hudon Ève-Marie , Lymburner Matthew
Published: May 2022

Introduction

The COVID-19 pandemic and resultant containment effects has had a detrimental effect on individuals’ social, occupational and financial circumstances. Taking a person-centred approach to inquiry and data analysis, we sought to identify classes (or segments) of employees with distinct configurations of responses across several pandemic-related stressors. We also investigated purported risk and resilience factors of membership in these classes.

Methods

We analyzed data from 4277 employees who completed a pulse survey in August 2020, using latent class analysis to identify classes of employees with unique patterns of responses across six pandemic-related stressors. We also conducted a multinomial logistic regression analysis to explore the associations between several risk and resilience factors (e.g. age, gender, perceived organizational support) and class membership, and we compared the emergent classes’ levels of self-reported mental health

Results

The data revealed four unique classes of employees: “adapting,” “conflicted,” “insecure” and “stressed” (30%, 35%, 21% and 14% of the sample, respectively). All of the risk and resilience factors were associated with being in the adapting class versus the other classes. The adapting employees also showed the most positive self-reported mental health relative to their counterparts.

Conclusion

By identifying classes of employees with distinct configurations of pandemic-related stressors, as well as differential risk factors and levels of self-reported mental health, the present study offers a starting point for informing work-related interventions with the goal of helping employees most vulnerable to pandemic-related stressors effectively cope with these stressors.
Contextualizing New Woman in Manju Kapur’s Custody
Authors: Namchoom Nang Wishakha , Nayak Prof. Bhagabat
Published: May 2022

New woman is a concept which addresses and accentuates women’s capabilities and struggle in patriarchal society. The term is referred to women who exercise control over their own lives in personal, social and economic matters, and pursue their own desires. The concept as a consciousness emerges due to social and cultural changes, rise of urban centers, increased immigration, industrialization, growing influence of consumer culture and changes in the structure of labour force. The concept appeared in late Victorian fiction with the intention to focus on women and about woman from the standpoint of woman. Chiefly New Woman expresses their dissatisfaction with contemporary position of women in marriage and society. Manju Kapur’s Custody registers significant aspects of new woman i.e destigmatizing infertility in the novel. She presents this as newness in woman in her thinking and to lift the social disparity between men and women. The paper attempts to explore the concept of new woman and theoretically to understand ‘home space’ and ‘public space’ of woman that kills and diminishes the status and position of woman in a traditional Hindu society.
Women Sensitiveness in Girish Karnad's the Fire and the Rain Hayavadana and Nagamandala
Authors: Devi. M Dr. Nirmala
Published: May 2022

In traditional Indian society, women are ruthlessly deprived of the opportunity to express their true feelings publicly. In Girish Karnad's works, female characters constantly rebel against the traditional position of women in Indian society and try to find their own way. His works make fun of the unjust values ??of the patriarchal society, which does not care about women's feelings and regards women as only inferior people who are absolutely loyal to him. Call it Nagamandala, Hayavadana and The Fire and the Rain, all these elements are everything. The exploitation and oppression of women has become an established culture of male chauvinism, so his works represent a meeting point where women are portrayed as enlightened and liberated with resistance. Girish Karnad strives to overcome male dominance, hoping to raise awareness of how women are exploited and abused in the name of marriage. Karnad started her work to meet the challenge of resolving controversial issues. As for women, she has experience in discriminatory politics that supports gender and caste paradigms.
The Realization of Directive Illocutionary Act of Male and Female English Teachers in Junior High School
Authors: Amalia Euis . , Husein Rahmad . , Pulungan Anni Holila
Published: May 2022

This study deals with Directive Illocutionary Act of male and female English Teacher in SMP Ad-Durrah Medan. The objectives of this study is to describe the realization of directive illocutionary act of male and female English teachers at SMP Ad-Durrah Medan. This study applied qualitative descriptive method. The techniques for collecting data are through applying observation by taking eight meetings for male and female English teachers to get realization of directive illocutionary act by male and female English. The results of this study found that realization of directive illocutionary act realized from the collaborative, competitive, conflictive , and convivial,  where one of the realization was showed that  the teacher makes a group discussion for doing the task and the teachers help the students by making a discussion for each student, making a collaboration for their task related to the content of their lesson and presenting the discussion in the class.
TRANSITIVITY SYSTEM IN CNN ONLINE NEWS
Authors: Qomariah Nurul . , Saragih Amrin . , Murni Sri Minda
Published: May 2022

This study was concerned with the types of transitivity system elements in CNN Online News. The objectives of this descriptive qualitative study were to discover: (1) the types of transitivity system, (2) the realization of transitivity system, and (3) the reasons for transitivity system realized in CNN Online News. The data of this study were clauses that consist of a transitivity system in 10 Covid-19 Online News taken from CNN Online News. The results of the study showed that: 1) CNN Online News realized all the types of process: Material, Mental, Relational, Behavioral, Verbal, and Existential process. The dominant process was Material Process. It was realized 214 (50,47%). CNN Online News realized participants: Actor, Goal, Sayer, Carrier, Attribute, Verbiage, Senser, Phenomenon, Target, Existing, Existence, Behaver, Token, Value, Receiver, Behavior, and Range. Actor and Goal were dominantly realized in the clauses of CNN Online News, there were 167 (26,38%) of Actor and 141 (22,27%) of Goal. The most dominant was Actor, and CNN Online News realized circumstances: Location, Cause, Manner, Accompaniment, Extent, Matter, Angle, and Role. It was realized 193 (60, 50%). The dominant was Location; 2) There were congruent realization and incongruent realization of transitivity system. The most dominant realization was congruent realization; 3) The reason why the types of transitivity system realized in CNN Online News is based on the context of the situation related to the field. Field stand for three entries, namely arena/social activity [+institutionalized/-institutionalized], participant’s characteristics [person/social] and semantic domain [+specialized/-specialized]. The most dominant was arena/social activity, especially [-institutionalized]. Keywords: Metafunction, Transitivity System, Online News, CNN
Simple qualitative dynein model in Nose-Hoover framework
Authors: Rosenberg Josef , Krejčová Milada
Published: May 2022

The presented paper is devoted to studying the dynein molecular motor and its stochastic description. The model aims to obtain good results comparable to literature sources qualitatively. We choose the Hoover-Holian oscillator to describe the dynein behaviour of each of its legs. It can catch the stochastic movement produced by Brownian motion and can be modified to simulate a load.
Global Perspectives on Megatrends
Authors: Kuhn Subin
Published: May 2022

Berthold M. Kuhn and Dimitrios L. Margellos present a thoroughly reflected analysis of global trends shaping our future. Key megatrends include climate change and sustainability, digitalization, growing inequalities, urbanization and smart cities, the progression toward a green economy, and sustainable finance. Addressing geopolitical shifts and the future of multilateralism, the authors also discuss new trends in democracy and governance, migration, and health and nutrition, as well as civilizational developments like demography, diversity, identity politics, individualization, and shifting gender norms. Based on their own research and a series of interviews with leading analysts and researchers from different world regions, the authors present cutting-edge content on the future of humanity.
The Nobel Prize in Physiology or Medicine 2018 was awarded to Cancer Therapy by Inhibition of Negative Immune Regulation
Authors: Furukawa Fukumi
Published: May 2022

On October 1, The Nobel Prize in Physiology or Medicine 2018 was awarded jointly to Dr. James P. Allison and Dr. Tasuku Honjo "for their discovery of cancer therapy by inhibition of negative immune regulation.The Nobel Assembly at Karolinska Institute released the comments that Dr. Allison and Dr. Honjo showed how different strategies for inhibiting the brakes on the immune system could be used in the treatment of cancer [1-5]. The seminal discoveries by the two laureates constitute a landmark in our fight against cancer. https://www.nobelprize.org/prizes/medicine/2018/prize-announcement/I sincerely wish to congratulate two recipients, co-workers and many patients cooperated in clinical trials. In this journal, we have published several reviews and papers on immunity checkpoints so far. The reason is that the mission of this journal is in scientific awareness and dissemination of new immunotherapy.I herein introduce briefly my previous report with some modification [6]. Immune checkpoints inhibitors (ICIs) have opened promising avenues in the treatment of cancer. Various blocking antibodies targeting programmed cell death -1 (PD-1) and cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) are approved for human use. They significantly improved disease outcome in a number of cancer patients by boosting anti-tumor immune responses. As Seidel, Otsuka and Kabashima described in their review article [7], mortality among advanced stage patients and the frequency of treatment-related adverse events remain high with current treatment. And, it is also noteworthy that unexpected immune related adverse effects (irAEs) appear, even when it becomes better to be administered to many cancer patients [8]. Unfortunately, the mechanisms of endocrine irAEs by ICIs, remain unclear, and optimal prevention, prediction, and treatment of the irAEs are still uncertain. However, appropriate uses and index setting related to prognosis are being studied in many fields such as dermatology [9] and other organs [6,7].While solving such problems, we have to understand that the mechanisms of immunogenic cell death are now moving from concepts to the clinic. We will explain the mechanism behind ICD and how it will perhaps breathe a new life into chemotherapy use in cancer, not front and center but as a helpful hand to immunotherapy [10].For a long time many scientists or doctors attempted to engage the immune system in the fight against cancer. Many clinicians stared at cancer patients who were to be dying by their side, mourning their inability. However, cancer therapy by inhibition of negative immune regulation checkpoint therapy has fundamentally changed the way we view how cancer can be managed and many patients will receive much better care and cure.