bluuebunny/crossref_metadata_2025 huggingface dataset:
COVID-19 Lockdown Policy and Heterogeneous Responses of Urban Mobility: Evidence from the Philippines
Authors: Jiang Yi , Laranjo Jade R. , Thomas Milan
Published: May 2022

This paper analyzes data from cellphone-based origin-destination flows to assess the effect of community quarantines on urban mobility in the Philippines after the initial outbreak of COVID-19 in 2020. The analysis of 2020 data reveals that the impact of lockdowns was strongest and most persistent in cities where a high share of workforce was employed in work-from-home friendly sectors or medium and large enterprises. The paper compares findings with cross-country evidence on lockdowns and mobility, discusses the economic implications for containment policies in the Philippines, and suggests directions for additional research.
The Effect of Interventions to Prevent Type 2 Diabetes on the Development of Diabetic Retinopathy: The DPP/DPPOS Experience
Authors: White Neil H. , Pan Qing , Knowler William C. , Schroeder Emily B. , Dabelea Dana , Chew Emily Y. , Blodi Barbara , Goldberg Ronald B. , Pi-Sunyer Xavier , Darwin Christine , Schlögl Mathias , Nathan David M. , Group the Diabetes Prevention Program  Research
Published: May 2022

  

OBJECTIVE:

To determine whether interventions that slow or prevent the development of type 2 diabetes mellitus in those at risk reduce the subsequent prevalence of diabetic retinopathy. 

RESEARCH DESIGN AND METHODS: 

The Diabetes Prevention Program (DPP) randomized subjects at risk for developing type 2 diabetes because of overweight/obesity and dysglycemia to either metformin (MET), intensive lifestyle intervention (ILS) or placebo (PLB) to assess the prevention of diabetes. During the DPP and DPP Outcome Study (DPPOS), we performed fundus photography over time on study participants, regardless of their diabetes status. Fundus photographs were graded using the ETDRS grading system with diabetic retinopathy defined as typical lesions of diabetic retinopathy (microaneurysms, exudates or hemorrhage, or worse) in either eye.

RESULTS: 

Despite reduced progression to diabetes in the ILS and MET groups compared to PLB, there was no difference in the prevalence of diabetic retinopathy between treatment groups after 1, 5, 11 or 16 years of follow up. No treatment group differences in retinopathy were found within prespecified subgroups (baseline age, sex, race/ethnicity, baseline BMI). In addition, there was no difference in the prevalence of diabetic retinopathy between those exposed to metformin and those not exposed to metformin regardless of treatment group assignment.

CONCLUSION: 

Interventions that delay or prevent the onset of type 2 diabetes in overweight/obese subjects with dysglycemia who are at risk for diabetes do not reduce the development of diabetic retinopathy for up to 20 years.
Att bli en sjungande tonårspojke: En livshistoria om att sjunga tillsammans med andra i skolan
Authors: Hentschel Linn
Published: May 2022

This chapter aims to present knowledge about teenage boys’ experiences of singing together in school. The study that the chapter is based on uses a phenomenological, gender theoretical and music didactic perspective. Earlier research shows that singing is practiced, and anticipated to be practiced more often by girls than boys in Western societies and schools. An analysis of interviews with the student Andreas and his music teacher Victor is presented, as they explore co-singing in a music profiled class in elementary school. The interviews were performed in 2013 and 2020, and analysed and presented as a «life story». It entails Andreas’ journey from being a teenage boy who refuses to sing in school to becoming a teenage boy who sings, and the role that Victor, as a music teacher, plays in Andreas’ journey. The chapter shows several gendered and pedagogical aspects in Andreas’ situation that influence him to at first mime and later on sing during choir lessons – especially the perception of singing as feminine coded and singing knowledge in choir.
Små russiske hverdager
Authors: Lieng Kristoffer
Published: May 2022

Små russiske hverdager är norsklektorn Torunn Berntsens oredigerade minnesbilder av livet i det sena 1990-talets Ryssland. Navet i berättelsen är köket hos Berntsens hyresvärdinna i Sankt Petersburg, där en stor del av vardagen försiggår och funderingar uppstår. Författaren grubblar mycket över Rysslands väsen och framtid.
Små russiske hverdager (An Average Day in Russia) are Norwegian lecturer Torunn Berntsen's unedited memoirs of life in late 1990s Russia. The hub of the story is the kitchen at Berntsen's landlady in St. Petersburg, where a large part of everyday life takes place and thoughts arise. The author ponders a lot about Russia's essence and future.
Teknik Pola Bilangan dan Hasil Belajar Operasi Pembagian Dalam Pembelajaran Matematika Siswa Madrasah Ibtidaiyah Kelas IV
Authors: . Kadir , Rosiyanti Hastri
Published: May 2022

Tujuan dari penelitian ini adalah untuk mempelajari penggunaan teknik pola bilangan dan kemampuan siswa dalam operasi pembagian di sekolah dasar. Penelitian dilakukan di Madrasah Ibtidaiyah di Ciputat dengan metode quasi eksperimen dengan melibatkan 60 sebagai sampel. Pemilhan sampel menggunakan cluster random sampling. Studi ini menemukan bahwa: 1) hasil belajar operasi pembagian siswa yang menggunakan teknik pola bilangan ini lebih tinggi dari mereka yang menggunakan teknik biasa dan 2) kemampuan siswa yang menggunakan teknik pola bilangan ini lebih baik daripada siswa yang menggunakan teknik biasa. Terbukti dalam penerapannya, siswa dapat mencantumkan bilangan yang dibagi, pembagi, hasil bagi lebih mudah dalam materi operasi pembagian.
Strategi REACT dalam Mengembangkan Kemampuan Berpikir Kreatif Matematis
Authors: Muin Abdul , Fitri Isnaeni
Published: May 2022

Artikel ini menjelaskan tentang penerapan strategi REACT dan kemampuan berpikir kreatif matematis siswa yang meliputi kemampuan berpikir lancar, kemampuan berpikir luwes, kemampuan berpikir asli dan kemampuan berpikir rinci. Penelitian dilakukan di Madrasah Tsanawiyah di Jakarta dengan menggunakan metode quasi eksperimen yang melibatkan 55 siswa sebagai sampel. Hasil temuan menunjukkan bahwa: a) Kemampuan berpikir kreatif matematis siswa yang awalnya rendah meningkat setelah diterapkan strategi REACT dan lebih baik dari pada siswa yang pembelajarannya dilakukan secara konvensional; b) Strategi REACT dapat mewadahi siswa untuk mengembangkan kemampuan berpikir kreatifnya terutama pada aspek kelancaran dan keluwesan berpikir; c) Terdapat relasi “berpengaruh positif” antara strategi REACT terhadap aspek kemampuan berpikir kreatif matematis;
Pendidikan Karakter Melalui Mathematical Habits Of Mind
Authors: Susanti Ely
Published: May 2022

Pendidikan karakter tidak hanya sekedar mengajarkan sopan santun atau ketaatan dalam menjalankan ibadah tetapi juga pada pembentukan pribadi yang seutuhnya dengan tujuan menyiapkan generasi yang mampu berpikir cerdas serta mampu beradaptasi dalam situasi yang tidak menentu. Pendidikan karakter ini dapat dilakukan melalui pembiasan-pembiasaan. Salah satunya adalah pembiasaan pikiran atau yang dikenal dengan mathematical habits of mind. Makalah ini membahas tentang hakikat pendidikan karakter dan mathematical habits of mind, serta bagaimana hubungan pendidikan karakter dan mathematical habits of mind. Hasil pembahasan menunjukkan bahwa banyak karakter-karakter yang dapat dikembangkan melalui mathematical habits of mind diantaranya bertanggungjawab, kritis, kreatif dan lain-lain
Membangun Kemampuan Komunikasi Matematik dan Nilai Karakter Siswa melalui Bentang Pangajen Berbantuan Phet interactive simulation
Authors: Soekisno Bambang Aryan
Published: May 2022

Hasil belajar siswa untuk bidang studi matematika, cukup mengkhawatirkan terutama kemampuan komunikasi matematik bahkan mungkin lebih rendah bila dibandingkan dengan kemampuan lainnya. Beberapa pelajar tidak menyukai matematika karena matematika penuh dengan hitungan dan miskin komunikasi. Beberapa pelajar juga berpikir bahwa matematika pelajaran yang membosankan, karena penuh rumus dan miskin nilai karakter.  Kebanyakan pelajar tidak merasa senang ketika belajar matematika. Bentang pangajen berbantuan Phet interactive simulation adalah sebuah pembelajaran yang menyajikan pembelajaran matematika dengan menyenangkan dan juga membangun keterampilan komunikasi dan nilai karakter. Ada lima langkah dalam pembelajaran dengan bentang pangajen, yaitu bina suasana, bina konsep, bina ingatan, beri bintang, dan beri hikmah.  Metode yang digunakan adalah penelitian tindakan kelas pada siswa SMA Negeri 6 Bogor. Keterampilan komunikasi terbangun pada langkah ke tiga sampai lima dari pembelajaran dengan bentang pangajen berbantuan Phet interactive simulation.  Adanya peningkatan kemampuan komunikasi matematik dari setiap siklus, dan nilai karakter siswa terbangun pada langkah ke empat dan lima dari pembelajaran ini.
Jelajah Alam Sekitar Dengan Strategi Partisipatif Dan Pendekatan Sistem Among Sebagai Suatu Upaya Meningkatkan Minat Dan Prestasi Belajar Himpunan Siswa Kelas Vii J SMPN 1 Cikampek.
Authors: Ratnaningsih Cucu
Published: May 2022

Rendahnya minat dan prestasi belajar matematika disebabkan berbagai faktor. Alternative solusi untuk mengatasi rendahnya minat dan prestasi belajar siswa kelas VII J menggunakan strategi partisipatif, pendekatan sistem among, dan tehnik praktek lapangan dengan sumber belajar lingkungan sekitar sekolah dalam pembelajaran materi himpunan. Instrumen yang digunakan selama penelitian adalah pre tes dan pos tes, lembar observasi, dan angket. Hasil penelitian selama dua siklus sebagai berikut: siswa dan guru setuju terhadap penggunaan strategi pembelajaran, minat siswa tinggi, dan prestasi siswa mengalami peningkatan yaitu pada siklus 1 rata-rata pre tes 58,2 (kategori kurang), pada pos tes meningkat menjadi rata-rata 78,3 (kategori baik) dan pada siklus 2 rata-rata pre tes 18,0 (kategori sangat kurang), pada pos tes meningkat menjadi rata-rata 66,9 (kategori cukup)Berdasarkan hasil kegiatan ini, dapat disarankan agar dalam pembelajaran himpunan digunakan strategi pembelajaran partisipatif dan tehnik praktek lapangan (jelajah alam sekitar) dan mata pelajaran lainpun dapat menggunakan strategi pembelajaran partisipatif dan tehnik praktek lapangan dengan sumber belajar lingkungan.
“It’s All in Your Head”
Authors: Friesen Phoebe , Dionne Émilie
Published: May 2022

In this contribution, we examine three stories of beneficent deception in medicine: the placebo machine invites children with treatment-resistant disorders to enter a high-tech machine and let their brains heal themselves; dementia villages extend validation therapy to the lived environment of geriatric care, supporting the illusion of living in the past through architecture; provocative testing relies on tricking patients suspected of fakery into experiencing seizures so that they can receive an expedited diagnosis. Enlisting the concept of misdirection from the realm of magic and theoretical contributions related to ‘stories’ and ‘storying practices’ from Feminist Science and Technologies Studies, we ask of each: Who is being deceived? Which ‘characters’ are given voice when these stories are told? How is deception justified? Following this, we question the onto-epistemological assumptions of reality and causation underlying each story and offer concluding thoughts on how ‘magic’ could be embraced within medicine and research.
Following Misdirection and Multiple Malarias in Santo Domingo, Dominican Republic
Authors: Keys Hunter
Published: May 2022

Misdirection can be understood as a social process of pursuing certain kinds of evidence while drawing attention away from others. This paper explores misdirection in the context of malaria elimination in the Dominican Republic. Malaria has recently exploded in impoverished spaces of the capital, Santo Domingo. Using ethnographic material collected from 2018-19, three perspectives trace the social co-production of misdirection. First, a young man afflicted with fever and weakness understands his ailment as “stress sickness” brought on by poverty and structural violence. Second, clinicians focus on the results of hemograms to diagnose febrile patients, creating a pattern of misdiagnosis. Lastly, malaria policies and financing demand more indicator data, creating the appearance of a neutral reality separate from local histories and political tensions. In the end, misdirection obscures malaria’s multiplicity, or the alternative realities that arise among the social actors who live with and respond to the problem of malaria in the capital. Attention to social-material practices breaks out of the narrow conceptualization of malaria as ‘only’ a parasitic disease and reveals its other, multiple manifestations that require more than techno-biomedical solutions alone.
Legitimidad: ¿el dilema de China?
Authors: Oviedo Eduardo Daniel
Published: May 2022

Este artículo analiza la legitimidad en China y amplía la tradicional división tripartita entre legitimidad de origen, desempeño y destino. Asimismo, divide la legitimidad de origen en legitimidad de las instituciones y legitimidad de las autoridades, y considera que crisis, eficacia e incertidumbre son tres términos clave para entender el estado actual de la legitimidad en este país. Es decir, una legitimidad de origen en crisis desde 1989, la efectividad de los resultados de la modernización, y la incertidumbre sobre si el régimen mantendrá su legitimidad actual. Por el momento, el Partido Comunista Chino utiliza argumentos multifacéticos para explicar la dominación política basados principalmente en los logros socioeconómicos, pero como éstos son inestables, insta a reinventar sus fuentes. En este sentido, las propuestas teóricas oscilan entre el confucianismo y la democracia, con punto medio en el neoconfucianismo moderno. Sin embargo, el gobierno comunista sigue un derrotero conservador, si bien el presidente Xi Jinping introdujo procedimientos tradicionales en la enmienda constitucional de 2018.
Collective Impact Partnerships: The Data to Action Hourglass Model
Authors: Monsen Karen , Drake Diana , Looman Wendy , Peterson Barbara , Ruud Maria , Smith Sheila , Pesut Daniel
Published: May 2022

Models are needed to guide positive health care and social transformation using real-world data, particularly in an era of data-driven science and accountability. We describe the Data-to-Action Hourglass Model, which synthesizes ideas of collective impact, partnership theory and practice, knowledge complexity, design justice, and systems thinking toward this goal. The Hourglass Model is an ecological (nested) perspective, placing knowledge management within the context of health at levels ranging from planetary to personal, and then using knowledge to inform collective action to influence policy. We offer in-depth commentary and resources to guide use of the Hourglass Model in research, education, and practice, and invite collaboration and discourse related to the model.
Experimentation and Modeling of Laser Radiation Scattering Through Carbon Fiber Reinforced Polymers
Authors: Shepard Steven P. , Yuen Walter W. , Lynch James H. , Maser Jaykob N. , Swaminathan Arvind , Fabris Drazen
Published: May 2022

With the prevalence of carbon fiber reinforced polymers (CFRPs) in aerospace platforms, there is a need to better understand radiative heat transport through the material. A laboratory experiment was constructed and computational Monte Carlo (MC) model optimized to quantify and understand the laser-scattering properties of CFRPs. The transmission data were analyzed by a zonal MC (ZMC) method to determine the material’s albedo and extinction coefficient, which can then be used for platform-level aerospace models to predict heat transfer more accurately through CFRP structures. This paper considers the effects of nodal, substrate, and detector plane sizing, as well as laser beam parameters, on matching albedo and extinction coefficient predictions from the ZMC method to experimental test data. Average albedo values for IM7/977-3 CFRP using the anchored ZMC method are 0.78 and 0.81 with one-ply and two-ply samples, respectively, having standard deviations of 0.11 and 0.09. Extinction coefficient predictions are 109.4 and [Formula: see text] with standard deviations of 28.3 and [Formula: see text] for one-ply and two-ply samples.
Post-acne symptom complex. Approaches to therapy
Authors: Drozhdina Marianna B. , Bobro Varvara A. , Sennikova Yuliana A. , Kornilova Evgeniya I.
Published: May 2022

Postacne-persistent skin changes that appear as a result of long-term acne, inadequate therapy and manipulations performed in the management of this group of patients. The post-acne symptom complex is stable skin changes that appear as a result of long-term acne inadequate therapy and manipulations performed during the management of this group of patients. The pathogenetic mechanisms underlying the launch of acne currently look as follows: androgens cause hyperseborrhea, sebum lipids activate innate immunity; pathological keratinization due to the production of IL-1 inflammatory mediator and androgen hyperproduction; Cutibacterium acnes activate innate immune responses through toll-like receptors and metalloproteinases, stimulate the production of antimicrobial peptides and sebum production. The subsequent rupture of the follicles activates the wound healing process. Depending on the genetically determined features of the course of the inflammatory process, various individual postacne changes of the skin will prevail in different patients. The article highlights the main factors influencing the formation of post-acne, pathogenetic mechanisms underlying the formation of these changes, systematizes modern data on the classification, morphological and pathohistological characteristics of scars. Quantitative and qualitative scales of assessment of post-acne scars for determining the severity of the pathological process are presented, differentiated approaches to modern methods of therapy are discussed in detail, including the advantages and disadvantages of the most common methods of treating patients based on the principles of evidence-based medicine using a number of personalized methods.
Scleroderma-like form of lipoid necrobiosis in a patient with idiopathic thrombocytopenic purpura
Authors: Perlamutrov Yuriy N. , Svishchenko Svetlana I. , Pugner Anna S.
Published: May 2022

A 33-year-old female patient with idiopathic thrombocytopenic purpura complained of rashes on the skin of the lower extremities, accompanied by moderate itching and a feeling of skin tightness, as well as a histologically verified diagnosis of lipoid necrobiosis. A combined treatment was carried out with the glucocorticosteroid Methylprednisolone at a dose of 32 mg per day in combination with PUVA therapy with 0.3% solution of ammi majus fructuum furocumarines, with a positive effect in the form of a decrease in the color intensity and induction of rashes, under the control of platelet levels. When using the method of PUVA-therapy with 0.3% solution of ammi majus fructuum furocumarines, there was an improvement in the 8th phototherapy procedure, however, due to a decrease in the level of platelets in the blood, the course of phototherapy was suspended.
The method of PUVA therapy with 0.3% solution of ammi majus fructuum furocumarines turned out to be clinically effective in the treatment of lipoid necrobiosis, however, the presence of concomitant pathology in the patient requires an interdisciplinary approach to the choice of treatment tactics.
Medicinal Chemistry of Oligonucleotide Drugs - Milestones of the Past and Visions for the Future
Authors: Hall Jonathan , Ashkinadze Anastasia , Becker Jan Philipp , Laski Artur , Manz Eva-Maria , Moravčík Štefan , Sjöström Sebastian , Vincent Mathilde
Published: May 2022

The oligonucleotide therapeutics field has blossomed in recent years, with thirteen approved drugs today and the promise of accelerated growth in coming years. Much of the progress in this field is due to advances in the medicinal chemistry of oligonucleotides,combined with a judicious choice of molecular targets and disease areas. In this perspective, we describe the growth of this new class of drugs highlighting selected milestones in oligonucleotide medicinal chemistry.
Teaching Acid-Base Equilibria by Using Log-log Diagrams
Authors: Togni Antonio
Published: May 2022

The purpose of this column consists in illustrating the utility of log-log diagrams for the graphical determination of the pH value of acid-base systems in dilute aqueous solution. This methodology allows to tackle systems going well beyond the case of mono- or diprotic acids, providing fast and accurate estimations of the pH. It is also argued that the use of so-called Sillén diagrams affords a better understanding of complex acid-base systems.
Blue LED Mediated C-H and N-H Insertion of Indoles into Aryldiazoesters and Iodonium Ylides
Authors: Gremaud Ludovic , Sen Subhabrata
Published: May 2022

Herein we have discussed projects related to blue LED mediated C-H and N-H insertion reaction in indoles and related heterocycles with aryl diazoesters and iodonium ylides as sources of carbenes. Blue LED effectively facilitates these conversions and was optimized from the option of numerous other LED lights. No metal catalysts were required. The reactions provide formation of differently alkylated indoles, pyrroles and furans. Control experiments and DFT calculation were used to understand the mechanism of reactions. As an application compounds bearing azepino[4, 5-b]indole and spiropiperidino indole building blocks were synthesized from the alkylated products.
Kebugaran jasmani pada siswa yang mengikuti ekstrakulikuler futsal
Authors: Suryadi Didi , Rubiyatno Rubiyatno
Published: May 2022

Penelitian ini bertujuan untuk mengetahui tingkat kebugaran jasmani pada siswa ekstrakulikuler futsal. Penelitian desktiptif kuantitatif menggunakan metode survei. Dilakukannya tes dan pengukuran menggunakan instrumen sesuai dengan Tes Kebugaran Jasmani Indonesia (TKJI) usia 13-15 tahun untuk menentukan kebugaran jasmani siswa. Sampel penelitian berjumlah 20 siswa putra yang mengikuti ekstrakulikuler futsal di Madrasah Tssanawiyah Negeri 1 Pontianak. Data yang diperoleh dilapangan berupa hasil tes dan pengukuran kebugaran jasmani dengan TKJI. Selanjutnya data dianalisis dengan deskriptif persentase, perhitungan dibantu dengan menggunakan Software Microsoft Excel. Hasil penelitian terdapat 5 siswa kategori sedang dengan persentase 25%, 14 siswa kategori sedang dengan persentase 70% dan katagori kurang sekali 5% sebanyak 1 siswa. Kesimpulan tingkat kebugaran jasmani pada siswa ekstrakulikuler futsal masih rendah dan berada pada kategori kurang.
Nickel-Catalyzed Reductive Alkylation of Heteroaryl Imines
Authors: Brandstätter Marco , Turro Raymond F. , Reisman Sarah
Published: May 2022

A Ni-catalyzed reductive cross-coupling of heteroaryl imines with C(sp3) electrophiles for the preparation of heterobenzylic amines is reported. This umpolung-type alkylation proceeds under mild conditions, avoids the pre-generation of organometallic reagents, and exhibits good functional group tolerance. Mechanistic studies are consistent with the imine substrate acting as a redox-active ligand upon coordination to a low-valent Ni center. The resulting bis(2-imino)heterocycle·Ni complexes can engage in alkylation reactions with a variety of C(sp3) electrophiles, giving heterobenzylic amine products in good yields.
Remarkable Piezofluorochromism of an Organoboron Complex Containing [2.2]Paracyclophane
Authors: Irii Shun , Ogaki Takuya , Miyashita Hana , Nobori Kazutaka , Ozawa Yoshiki , Abe Masaaki , Sato Hiroyasu , Ohta Eisuke , Matsui Yasunori , Ikeda Hiroshi
Published: May 2022

Piezofluorochromism (PFC) of crystals of a tert-butyl and [2.2]paracyclophane-containing diaroylmethanatoboron difluoride (pCP-tBu), which is expected to possess both intermolecular and intramolecular – interactions, was investigated. pCP-tBu crystals were found to exhibit remarkable PFC associated with an over 150-nm redshift of fluorescence (FL) wavelength occurring under increasing isotropic pressure applied by using a diamond anvil cell. X-ray crystallographic analysis showed that pCP-tBu molecules in the crystal at atmospheric pressure exist in the form of an intermolecular pi-stacking dimer through back-to-back pi–pi interactions. Moreover, the crystallographic data under high pressure showed that increasing isotropic pressure causes a reduction in both the intermolecular -stacking distance of the dimer (DINTER) and the intramolecular pi-stacking distance between two benzene rings in the [2.2]paracyclophane moiety (DINTRA). Density functional theory calculations, using the Cartesian coordinates obtained by X-ray analysis, suggest that the origin of PFC of pCP-tBu crystals is the reduction of the LUMO energy of the pi-stacking dimer and that the intermolecular pi–pi interaction is still the important factor leading to PFC of pCP-tBu crystals.
Evolutionary association of receptor-wide amino acids with G protein–coupling selectivity in aminergic GPCRs
Authors: Selçuk Berkay , Erol Ismail , Durdağı Serdar , Adebali Ogün
Published: May 2022

G protein-coupled receptors (GPCRs) induce signal transduction pathways through coupling to four main subtypes of G proteins (Gs, Gi, Gq, and G12/13), selectively. However, G protein selective activation mechanisms and residual determinants in GPCRs have remained obscure. Herein, we performed extensive phylogenetic analysis and identified specifically conserved residues for the aminergic receptors having similar coupling profiles. By integrating our methodology of differential evolutionary conservation of G protein–specific amino acids with structural analyses, we identified specific activation networks for Gs, Gi1, Go, and Gq. To validate that these networks could determine coupling selectivity we further analyzed Gs-specific activation network and its association with Gs selectivity. Through molecular dynamics simulations, we showed that previously uncharacterized Glycine at position 7x41 plays an important role in receptor activation and it may determine Gs coupling selectivity by facilitating a larger TM6 movement. Finally, we gathered our results into a comprehensive model of G protein selectivity called “sequential switches of activation” describing three main molecular switches controlling GPCR activation: ligand binding, G protein selective activation mechanisms, and G protein contact.
Teaching Emotionally Charged Cultural Diversity Topics in Family Science: The Pivotal Role of Instructors’ Emotions
Authors: Niehuis Sylvia , Thomas-Jackson Shera
Published: May 2022

Many family-science courses are devoted entirely to, or include segments on, cultural diversity. Though some experts believe that a certain amount of tension in the classroom can spur student introspection and learning, discussions that create intensely unpleasant experiences are likely to be counterproductive. Students’ learning may be impaired. Much of the available literature focuses on practical advice for instructors teaching challenging classes, and on students’ emotional reactions to the subject matter. Instructors’ emotions, which set the tone for students’ emotions, have received less attention. This paper focuses on instructors’ emotional skills and experiences in handling uncomfortable cultural diversity class discussions, including the “emotional work” involved and equitability in assignments to teach such classes. We first review published recommendations of best practices for dealing with difficult classroom situations, then present several outstanding questions. We present the latter, in part, to generate greater discussion and research on the relevant issues.
Historical Literacy and Cultural Competence in College Students Enrolled in Family Science Courses
Authors: Greiving Jennifer E.
Published: May 2022

Recent educational reforms tend to focus on reading and math, possibly to the detriment of history education. As university students enroll in family perspective courses, their lack of historical knowledge may result in diminished understanding of local and global events that have affected the course of global families and human development. This study examines the connection between students’ self-reported historical knowledge and cultural competence. Self-reported measures of historical literacy and cultural competency were collected from 123 students at a Mountain West urban university campus using a quantitative questionnaire. Results show that historical literacy may play a small but statistically significant role in cultural competence. Suggestions are made for future research and curriculum direction.
Pengaruh Proporsi Rumput Laut dan Sawo Mentega terhadap Serat Pangan, Aktivitas Antioksidan, Overrun, dan Sifat Organoleptik Sorbet
Authors: Sakti Astagina Sekar
Published: May 2022

Lack of fiber and antioxidants can increase the risk of obesity which lead to oxidative stress. Eucheuma cottonii seaweed contains dietary fiber which provide anti-obesity effects. Beside dietary fiber, antioxidant is also needed to prevent oxidative stress in obesity. Canistel fruit (Pouteria campechiana) contains antioxidants such as vitamin C, beta carotene and polyphenols. The purpose of this study was to determine the effect of the proportion of seaweed and canistel on the content of dietary fiber, antioxidant activity, physical properties, and organoleptic properties of sorbet. This research method used a one-factor completely randomized design (CRD) with two repetitions. These factors are the proportion of seaweed and canistel, namely F1 (20%:80%), F2 (30%:70%), and F3 (40%:60%). The ANOVA test results showed that the proportion of seaweed and canistel had a significant effect (p< 0.05) on the dietary fiber and overrun, while the antioxidant activity and organoleptic properties of sorbet had no significant effect (p >0.05). The selected formula by using Exponential Comparison Method (ECM) results the F1 formula with the proportion of 20%:80%. The selected formula products contained 5.19% dietary fiber, 48% w / v antioxidant activity, and 34.32% overrun.
IMPLEMENTASI PENGAKUAN DAN PENGHORMATAN TERHADAP MASYARAKAT HUKUM ADAT DAYAK IBAN SEMUNYING DAN KAITANNYA DALAM SUSTAINABLE DEVELOPMENT GOALS
Authors: Kurnia Christmas Sandy , Hardiyanti Marzellina
Published: May 2022

Lemahnya implementasi pengakuan dan penghormatan terhadap Masyarakat Hukum Adat Dayak Iban Semunying menjadi persoalan terkait adanya praktek-praktek diskriminasi didalam menjalankan suatu kebijakan pemerintah. Mengapa implementasi pengakuan dan penghormatan terhadap masyarakat hukum adat Dayak Iban Semunying masih lemah serta bagaimanakah prinsip-prinsip hak asasi manusia dan Sustainable Development Goals merupakan dua permasalahan yang diangkat dalam artikel ini. Dalam penelitian ini bertujuan untuk menemukan apa saja hal-hal yang menjadi dasar lemahnya perlindungan terhadap masyarakat adat. Hasil dari penelitian ini diharapkan dapat memberikan pandangan terhadap perlindungan hak-hak masyarakat adat yang berperspektif tujuan pembangunan berkelanjutan

KEYWORDS

Masyarakat Hukum Adat, Hak Asasi Manusia, Tujuan Pembangunan Berkelanjutan
PERTANGGUNGJAWABAN HUKUM PEMBEBASAN BERSYARAT NARAPIDANA SEBAGAI UPAYA DALAM PENCEGAHAN COVID 19.
Authors: Imam Sationo Teguh , Sulistyanto Luhukay Roni
Published: May 2022

Pembebasan bersyarat kepada warga binaan merupakan suatu Langkah yang revolusioner guna mencegah penyebaran covid 19, adanya kelebihan muatan warga binaan sangat membahayakan terhadap keselamatannya apabila ada yang tertular dan alasan kemanusian. Ini sangat berbading terbalik jika di kaitkan dengan narapidana koruptor yang tidak memiliki potensi terhadap penularan corona virus/ covid 19 hal ini di karenakan narapidana koruptor dalam tahanan memiliki fasilitas mewah dan tidak ada alasan kelebihan muatan terhadap narapidana koruptor, Pemberian pembebasan bersyarat koruptor seolah mematahkan usaha dan semangat bangsa ini untuk membangun memberantas tindak pidana korupsi. Pembebasan bersyarat ini juga berpotensi untuk tidak memberikan efek jera pada terpidana korupsi hal ini dikarenakan pembebasan bersyarat ini dapat menjadi jalan keluar untuk lari dari tanggung jawab atas kerugian negara akibat dari kejahatan korupsi yang telah dilakukan. Pembebasan Bersyarat di lakukan dengan tidak melalui mekanisme tersebut yang di atur dalam Undang-Undang Nomor 12 Tahun 1995 tentang Pemasyarakatan dan PP No. 99 Tahun 2012 hal ini di karenakan pencegahan terhadap pandemic corona virus atau covid 19. Pembebasan bersyarat yang di lasanakan oleh kementrian hukum dan Ham di dasarkan pada surat edaran dengan nomor PAS-497.PK.01.04.04 Tahun 2020 yang mengatur tentang pembebasan narapidana dan anak melalui asimilasi dan integrasi guna mencegah penyebaran virus Corona atau covid 19

KEYWORDS

Pembebasan Bersyarat, Narapidana, Covid 19
ABORSI DALAM PERPEKTIF AGAMA DAN HUKUM POSITIF DI INDONESIA
Authors: Hartanto Hartanto
Published: May 2022

Aborsi Dan Agama Dari Sudut Pandang Hukum Positif di Indonesia".
Aborsi adalah sebuah fenomena yang ada di masyarakat, tetapi solusi dari
hukum dan agama masih meninggalkan perdebatan, dari hal paling sederhana
mengenai definisi aborsi, aborsi dapat dipenuhi jika janin sudah dinyatakan,
maka unsur-unsur kehidupan ini pun waktu dapat ditentukan mulai. Jadi dari
sudut pandang melibatkan agama dan hukum positif. Menulis bermasalah
didasarkan pada aborsi khususnya ulasan agama dan hukum yang positif di
Indonesia. Memahami aborsi, menjadi pedoman bagi kita untuk berperilaku,
atau bahkan menjadi melakukan aborsi hukum dan mendorong pembentukan
positif dan mengakomodasi norma agama. Fakta tentang realitas aborsi
menunjukkan bahwa terus terjadi di sekitar kita dikaitkan dengan dasar-dasar /
teori. Pada kesimpulannya dalam pikiran bahwa aborsi adalah tindakan jahat,
namun perasaan seorang ibu sebagai subjek hukum patut dipertimbangkan
untuk memilah bahwa tidak semua aborsi ilegal, dan harus terus
dikembangkan untuk memenuhi realitas realitas rasa keadilan dalam
masyarakat.
Kata kunci: Aborsi, Agama, Hukum Positif
HOAX DI INDONESIA : SUATU KAJIAN
Authors: Widodo Wahyu , Budoyo Sapto , Windi Pratama Toebagus Galang , Soeprijanto Troeboes
Published: May 2022

Hoax atau berita Bohong belakangan sering beredar pada aplikikasi media
Sosial di Indonesia belakangan ini. tentu berdampak negatif terhadap berbagai
bidang di dalam bermasyarakat dan bernegara dimana salah satu sektor yang cukup
terkena dampak ialah sektor hukum. Maraknya Hoax di Indonesia tentu
mempengaruhi wibawa hukum Indonesia, karena dengan maraknya Hoax ini secara
tidak langsung membuktikan bahwa hukum di Indonesia masih belum mampu
menangani hal tersebut. Berdasarkan hal tersebut diatas maka penulis tertarik untuk
mengkaji bagaimana Hukum Indonesia menanggulangi Bahaya Hoax. Lewat
pendekatan yuridis normatif, Berita Hoax atau kabar bohong adalah perbuatan
Pidana karena melanggar pasal 28 ayat 1 UU Nomor 11 Tahun 2008 Tentang ITE
dengan ancaman Pidana penjara paling lama 6 (enam) tahun dan/atau denda paling
banyak Rp. 1.000.000.000,00 (satu miliar rupiah). ada beberapa faktor yang
menyebabkan Hoax marak di Indonesia seperti rendahnya minat baca masyarakat
Indonesia, dan rendahnya wibawa hukum Indonesia yang dipicu oleh beberapa
faktor seperti kurang mampunya pemerintah di dalam menyelesaikan kasus
pelanggaran HAM yang berakibat tingkat kepercayaan masyarakat terhadap
pemerintah yang rendah.
Kata Kunci: Hoax, Indonesia, Kajian
PERIZINAN SEBAGAI INSTRUMEN PEMANFAATAN HUTAN MASYARAKAT HUKUM ADAT
Authors: Wasiati Cunduk , Hartanto Hartanto
Published: May 2022

Konsep pengakuan hak masyarakat hukum adat di tuangkan dalam UndangUndang Dasar Negara Republik Indonesia Tahun 1945 Pasal 18B ayat (2) UUD 1945
yang menjelaskan bahwa Negara mengakui dan menghormati kesatuan-kesatuan
masyarakat hukum adat beserta hak-hak tradisionalnya sepanjang masih hidup dan
sesuai dengan perkembangan masyarakat. Masyarakat hukum adat akan diakui
sepanjang masih hidup dan sesuai dengan perkembangan masyarakat dan prinsip
Negara Kesatuan Republik Indonesia. Prinsip Perizinan Pemanfaatan Hutan
Masyarakat Hukum Adat merupakan Keinginan pemerintah dalam mengarahkan (
mengendalikan “ sturen” ) aktivitas aktivitas tertentu, Izin mencegah bahaya dari
lingkungan,Keinginan-keinginan melindungi objek tertentu, Izin hendak membagi bagi
benda yang sedikit, Izin memberikan pengarahan dengan menyeleksi orang-orang dan
aktivitas- aktivitas. Penguasaan hutan oleh negara tetap memperhatikan hak
masyarakat hukum adat, sepanjang kenyataannya masih ada dan diakui
keberadaannya, serta tidak bertentangan dengan kepentingan nasional. mengenai
eksistensi penghormatan terhadap hak- hak masyarakat adat. Dalam hal ini negara
tidak memiliki kekuasaan hukum untuk menjadikan hutan adat adalah hutan yang
berada di wilayah masyarakat hukum adat menjadi hutan negara.
Kata Kunci : Perizinan, Hutan, Masyarakat Hukum Ada
THE IMPLEMENTATION OF TRI CORE BREASTFEEDING MODELS ON MOTHER’S SATISFACTION IN BREASTFEEDING
Authors: Helina Siska , Harahap Juraida Roito , Halimah Siti
Published: May 2022

The low rates of exclusive breastfeeding have effected the growth and the development of children. Some efforts to improve the achievement of exclusive breastfeeding have been conducted, like an education about breastfeeding, facilitating early breastfeeding initiation and providing motivation to mothers. These elements contain a form of health promotion care model called the Tri Core Breastfeeding Models. The purpose of this study is to determine the effect of Tri Core Breastfeeding Models on breastfeeding mothers' satisfaction. This research was conducted in the working area of the Sidomulyo Health Center in Pekanbaru City in August 2019 to April 2020. This research is Pre-experimental Design. The population in this study was all third trimester pregnant women. The sample of 20 pregnant women was taken by consecutive sampling technique with 10 pregnant women in the intervention and 10 pregnant women for control. The Maternal Breastfeeding Evaluation Scale (MBFES) questionnaire was used to collect the data. The Mann Whitney Test with a significance level of 95% was used to analyze the data. The results showed that the average satisfaction of breastfeeding mothers in the intervention group was 134.80 (SD: 3.190) and the control group 119.10 (SD: 14.317), and it is found that there is a difference in breastfeeding satisfaction among mothers in the intervention group and the control group (p = 0.019). Finally, it is recommended that Tri Core Breastfeeding Models can be applied in providing midwifery care in the  to support the success of exclusive breastfeeding
ANALISIS KARAKTERISTIK NET PRIMARY PRODUCTIVITY DAN KLOROFIL-A DI LAUT BANDA DAN SEKITARNYA
Authors: Marpaung Sartono , Prayogo Teguh , Yati Emi , Dwi Purwanto Anang , Nandika M. Rizki , Dirgahayu Domiri Dede , Kushardono Dony
Published: May 2022

Net primary productivity (NPP) and chlorophyll-a (Chl-a) are indicators of water productivity. In this study, an analysis of NPP and Chl-a characteristics in the Banda Sea was carried out using the Hovmöller diagram and Pearson’s correlation. The NPP data used comes from VGPM and Chl-a from Aqua MODIS satellite. The results of data analysis from January 2003-December 2020, NPP and Chl-a reached highest concentrations in dry season and lowest in wet season. For monthly data, the highest concentrations occurred in August and the lowest in April and December. The waters of the Banda Sea include mesotrophic waters with monthly average of NPP 429 mg C/m2/day and Chl-a 0.24 mg/m3. During La Niña and El Niño, there was a change (decrease/increase) the concentration of NPP and Chl-a in dry season and transition period II. NPP and Chl-a have a high correlation and a strong linear relationship. NPP and Chl-a have almost the same pattern/tendency temporally. The change of NPP concentration temporally corresponded to change of Chl-a concentration. Seasonal factors, La Niña and El Niño have a strong influence in influencing the variability of NPP and Chl-a concentrations. High productivity based on NPP and Chl-a didn’t affect for skipjack and tuna seasons (big pelagic), that occurs in wet season and transition period II. High productivity affects to flying fish season (small pelagic) that occurs in dry season.
KUANTIFIKASI HAMBUR BALIK AKUSTIK DASAR LAUT MENGGUNAKAN SCIENTIFIC SINGLE BEAM ECHOSOUNDER
Authors: Elson La , Manik Henry Munandar , Totok Hestirianoto  , Sri Pujiyati
Published: May 2022

Teknologi hidroakustik mampu melakukan kuantifikasi terhadap substrat dasar laut dan dapat memperkirakan secara akurat dan mendekati real time terhadap karakter akustik yang dimiliki oleh masing-masing jenis substrat. Tujuan dari penelitian ini adalah melakukan kuantifikasi hambur balik akustik dasar laut dalam upaya pengembangan teknologi informasi kelautan. Akusisi data menggunakan instrumen akustik Single Beam Echosounder Simrad EK-15 pada frekuensi 200 kHz. Pengolahan dan analisis data meliputi hambur balik akustik, tipe sedimen, komputasi acoustics bottom backscattering substrat dasar laut dan analisis spasial acoustic backscattering dasar laut di perairan Pulau Lancang. Hasil penelitian ini menunjukkan bahwa nilai hambur balik akustik substrat dasar laut berdasarkan nilai SS dan ukuran partikel di setiap stasiun sampling yaitu tipe substrat pasir -21,08 dB sampai -24,55 dB, pasir halus -25,67 dB sampai -26,67 dB, dan pasir halus sekali berkisar antara -27,42 dB sampai -28,03 dB. Berdasarkan rentang nilai hambur balik akustik yang didapatkan dari stasiun sampling diperoleh klasifikasi jenis substrat dasar laut di sepanjang lajur survei yaitu pasir kasar sekali, pasir kasar, pasir sedang, pasir halus, pasir halus sekali, lanau kasar, lanau sedang, lanau halus, lempung kasar dan lempung halus pada rentang nilai -47,85 dB sampai -17,07 dB. Substrat pasir paling banyak ditemukan di lokasi penelitian dengan komposisi yang lebih besar dibandingkan dengan lanau dan lempung. Nilai hambur balik akustik sangat dipengaruhi oleh ukuran partikel, bentuk morfologi dan relief dasar laut.
ANALISIS KAWASAN BUDIDAYA RUMPUT LAUT (Kappaphycus alvarezii) BERDASARKAN INDIKATOR KESESUAIAN DAN DAYA DUKUNG DI PESISIR KOTA BAUBAU
Authors: Al Mualam Al Mualam , Widigdo Bambang , Zairion
Published: May 2022

Kappaphycus alvarezii merupakan salah satu spesies rumput laut yang mayoritas dikembangkan di kawasan pesisir dan memiliki nilai ekonomis yang cukup tinggi. Upaya dalam mengembangkan kawasan budidaya rumput laut membutuhkan pendekatan yang memperhatikan indikator kesesuaian dan daya dukung untuk menjamin keberlanjutan produksi rumput laut jenis tersebut di masa depan. Penelitian ini bertujuan untuk menganalisis kawasan budidaya rumput laut jenis K. alvarezii berdasarkan analisis kesesuaian dan daya dukung perairan dengan pendekatan konsentrasi nitrat (NO3-). Penelitian ini dilakukan di Pesisir Kota Baubau, Provinsi Sulawesi Tenggara pada bulan Februari–Maret 2020. Data parameter fisik dan kimia perairan dikumpulkan secara langsung di lokasi penelitian, sementara satuan konsentrasi nitrat yang mampu diserap rumput laut diperoleh dari data sekunder yang tersedia. Data parameter lingkungan diolah dengan metode weight sum overlay pada aplikasi image processing dan dilanjutkan dengan analisis daya dukung berdasarkan konsentrasi nitrat. Hasil analisis kesesuaian perairan diperoleh mencapai 3240,6 ha. Kategori sangat sesuai seluas 920,58 ha dan kategori sesuai 2320 ha. Daya dukung berdasarkan konsentrasi nitrat yang dapat ditampung oleh perairan adalah 0,497 kg-N/hari dengan total jumlah rumput laut yang dapat dibudidayakan dalam satu tahun adalah 7317,90 ton. Berdasarkan angka tersebut maka dapat disimpulkan bahwa sebagian besar Pesisir Kota Baubau potensial untuk dijadikan sebagai kawasan pengembangan budidaya rumput laut dengan jumlah produksi yang tinggi.
Community-building through political cartoons in Kenya, South Africa and Côte d’Ivoire
Authors: Louwagie Fransiska , Weidman Sarah , Bamberg Ingrid , Mwiti Betty , Levine Di , Illingworth James
Published: May 2022

This paper arises from a research project at the University of Leicester, led by Dr Fransiska Louwagie and Dr Di Levine, in collaboration with a broader team of research associates, in particular Drs James Illingworth and Sarah Weidman. The project built on external partnerships with Cartooning for Peace, an international organisation of press cartoonists, and Shout Out UK, an award-winning platform for political and media literacy. The project was funded by the University of Leicester’s Global Challenges Research Fund. It aimed to examine how political cartoons can foster dialogue and exchange in conflict or post-conflict contexts, particularly amongst young people. As a visual medium relying on humour, cartooning has the power to present critical questions in an open and non-threatening manner, triggering dialogue and meaning-making. In line with Sustainable Development Goal (SDG) 16 the project therefore set out to investigate how political cartoons can help to negotiate local and global tensions and how they engage audiences with conceptions and definitions of community and humanity. It aimed to shed new light on the question of how political cartooning can help to address challenges in (post-)conflict societies, where there is a recognised need for community-driven resilience building. Relating to this, through its focus on press cartoons, it sought to raise awareness of the need for access and freedom of information (SDG 16.10). Following an open call for projects, a commission was made for four series of workshops by external partners working in conflict-and post-conflict situations, in Kenya, Côte d’Ivoire and South Africa (see appendix for detailed aims of the call).
Immunohistochemical expression of Forkhead Box (Fox) A1 and P53 in epithelial ovarian cancer
Authors: Afaf T Elnashar , Esraa M Youssef
Published: May 2022

Background: Ovarian cancer (OC) is the fifth cause of cancer mortality in females. There were an estimated 300,000 new cases of OC diagnosed worldwide in 2018, corresponding to 3.4% of all cancer cases among women. The high mortality rate of OC attributed to asymptomatic growth of the tumor leads to its diagnosis at advanced stages. About 85% - 90% of OC are epithelial including serous, endometrioid, clear cell, and mucinous carcinoma. Aim: To study the immunohistochemical (IHC) expression of FOX A1 and p53 in epithelial OC and its association with prognostic indicators such as age, tumor size, stage, grade, and histological type. Materials and methods: The study included 52 cases with EOC from the pathology department, faculty of medicine, Aswan, and Sohag Universities, in the period from January 2017 to December 2019. This study involved 52 patients with OC and a median age of 53 years. Different histological types were included as 37 serous, 12 mucinous, 1 case endometroid 2 cases clear cell OC. The study cases were classified into 22 Grade I, 16 Grade II, and 20 Grade III. About 22 cases were at stage I, 9 at stage II, 11 at stage III, and 10 at stage IV. Tissue sections were stained using the IHC technique with FOX A1 at a dilution of 1:100 and p53 at 1:100. Results: A statistically significant correlation was found between FOX A1 expression and advanced patient's age, high grade, advanced stage, ruptured capsule, and ascites, regardless of tumor laterality. No significant association was found between p53 immunoexpression and the same clinic-pathological parameters although p53 was associated with serious type. Conclusion: FOX A1 immunoexpression in EOC is considered a poor prognostic factor in EOC. FOX A1 could be a potential therapeutic target and prognostic marker in EOC.