bluuebunny/crossref_metadata_2025 huggingface dataset:
Modeling of the compaction of powder filter elements during radial isostatic pressing
Authors:   Lutsk national technical university, Povstyanoy O. Y. , Mikhailov A. O. ,   National university of food technologies, Rud V. D. ,   Lutsk national technical university, Mikhailov O. V. ,   Frantsevich Institute for Problems of Materials Science of NAS of Ukraine
Published: April 2021

The method of computer simulation was used to study the process of radially isostatic pressing of filter elements made of steel powder BBS15. Powder compaction occurs under the influence of an elastic ele¬ment made of polyurethane. The volume of the deformable body is considered as a continuous medium. To describe the behavior of this medium, the relations of the theory of plasticity of a porous body and the finite element method are used. The patterns of compaction of products of two types are considered (hollow cylinders, including multilayer ones, and filters of complex shape in the form of a bulb). When pressing multilayer filters, the load was removed after compaction of each layer. A new powder was placed in the cavity between the obtained layer and the elastic element, which took its original shape. Further, the pressing process was continued. The porosity distribution in the case of compaction of a single-layer cylindrical filter is uneven. The value of porosity increases with increasing radius. As the degree of deformation increases, the difference between the porosity of the material at the inner and outer surfaces of the filter decreases. The compaction of the outer layer of the two-layer filter occurs in the same way as the preliminary compaction of the first (inner) layer. The denser inner layer deforms slightly and acts as a mandrel. Further, the outer layer is compacted and both layers are deformed. The compaction of the layers of a three-layer filter is similar. The thickness and porosity of the layers can be controlled by changing the initial porosity of the powder, the inner diameter of the elastic element, as well as the pressing load. Two compaction schemes (radial and axial) were considered in the manufacture of complex-shaped filters in the form of a bulb. The distribution of porosity is uneven and depends on the compaction scheme. The material of the filter wall is compacted more intensively in the case of radial pressing. The porosity is higher at the outer surface of the filter wall and lower at its inner surface.The bottom material of the filter is compacted more intensively in the case of axial pressing.The use of the pressing scheme, in which the powder is first compacted in the radial and then in the axial direction, allows to get a more uniform distribution of porosity. Keywords: radial isostatic pressing, porous permeable material, filter, density distribution, porosity.
Perspectivas y aplicaciones reales del grafeno después de 16 años de su descubrimiento
Authors: Urcuyo Solórzano Roberto , Cordero Solano Karla Vanessa , Gonzalez Flores Diego Andrés
Published: April 2021

A 16 años del gran descubrimiento del grafeno los focos de atención vuelven a estar en este material con el reporte de su comportamiento superconductor dependiendo del apilado de sus capas. Sin embargo, su nombre durante estos últimos años no solo se ha relacionado a la superconductividad, sino que ha sido relacionado con una diversidad muy amplia de aplicaciones, en disciplinas muy diversas, entre las que cabe mencionar: materiales opto-electrónicos, electrodos para catálisis, dispositivos para tratamiento de desechos, biosensores, entre otros. Esto ha hecho que un gran número de grupos de investigación se hayan interesado no solo en estudiar sus propiedades, sino también en investigar nuevos métodos sintéticos que puedan ser escalables a niveles industriales, sin perder sus propiedades electrónicas y mecánicas. A pesar de los numerosos estudios y los recursos invertidos en grafeno no todas las aplicaciones han llegado a ser una realidad, en esta revisión se muestran algunas de las más exitosas.
Desenvolvimento, estratégia e comunicação no discurso de líderes empresariais: o caso de Divinópolis, Minas Gerais
Authors: Raslan Filho Gilson Soares , Barros Janaina Visibeli
Published: April 2021

Este texto é um esforço para compreender como as estratégias de comunicação têm sido trabalhadas nas organizações privadas de Divinópolis, cidade polo da região Centro-Oeste de Minas Gerais, e como os processos comunicativos são compreendidos, em um cenário – histórico, mas também de mercado – em que a comunicação é tomada, ainda que difusamente, como elemento central para as organizações. Partindo do pressuposto de que há uma relação necessária entre desenvolvimento econômico, desenvolvimento social e estratégias de comunicação, o texto expõe resultados parciais de pesquisa empírica, que visou à análise dos discursos de lideranças empresariais da cidade sobre comunicação, estratégias e desenvolvimento.
Entrevista jornalística em vias de compreensão: o caminho do diálogo para a experiência da alteridade
Authors: Ventura Mauro De Souza , Abib Tayane Aidar
Published: April 2021

Desenvolvemos, neste estudo, uma reflexão sobre o procedimento jornalístico da entrevista, buscando no entrecruzamento teórico de Hans-Georg Gadamer (2002) e Martin Buber (1979, 1982) as pistas para inscrevê-la como fenômeno dialógico no qual é possível despontar a experiência de intercompreensão entre repórter e fonte. Partimos, para tanto, de uma discussão epistemológica acerca da Comunicação, de modo a fundamentá-la em perspectiva relacional, tal qual Wolton (2004, 2006), Sodré (2014) e Marcondes Filho (2004), e, assim, abrir caminhos para situar a prática jornalística em dinâmica de intersubjetividade, na qual pese o movimento de abertura em direção ao Outro.
Jornalismo de serviço e biopoder: uma análise de conteúdo de TV
Authors: Bertolini Jeferson
Published: April 2021

Este artigo apresenta resultados de pesquisa que relaciona jornalismo e biopoder (técnica de poder que busca produzir corpos economicamente ativos). O trabalho usa análise de conteúdo. Adota o programa Bem Estar, da Rede Globo, como objeto de estudo. O texto diz que o jornalismo colabora com o biopoder quando traduz e faz circular o saber médico, que cria normas relativas ao corpo. Essa colaboração, aparentemente involuntária, ocorre sobretudo em programas de televisão sobre saúde e bem-estar, via jornalismo de serviço. Palavras-chave: Jornalismo; Biopoder; Saúde
Wolontariat jako forma zatrudnienia przez parafie na przykładzie muzyka kościelnego
Authors: Nieczarowska Aleksandra
Published: April 2021

Niniejszy artykuł podejmuje próbę zmierzenia się z prawną oceną praktyki zatrudniania przez parafie rzymskokatolickie w Polsce wolontariuszy na stanowisku muzyka kościelnego (organisty). Formalnie tego typu umowy zakładają oczywistą fikcję sprowadzającą się do nierzeczywistego stwierdzenia, iż „pełnoetatowy” organista w kościele parafialnym jako wolontariusz nie otrzymuje wynagrodzenia od parafii ani od osób trzecich. Co istotne, umowa o wolontariat pozwala parafii na znaczne ograniczenie pracowniczych kosztów stałych związanych z odprowadzaniem podatku dochodowego lub składek na ubezpieczenia społeczne czy zdrowotne, wobec czego z punktu widzenia parafii wydaje się być dosyć atrakcyjną formą współpracy. Przepisy ustawy o działalności pożytku publicznego i o wolontariacie określają, że podmiotem korzystającym z pracy wolontariuszy może być parafia rzymskokatolicka, przy czym warunkiem koniecznym jest posiadanie przez parafię statutu przewidującego jako jeden z celów również działalność pożytku publicznego. Z punktu widzenia prawa kanonicznego oraz świeckiego powstanie parafii nie jest uzależnione od posiadania statutu regulującego funkcjonowanie tej kościelnej osoby prawnej. W tradycji Kościoła katolickiego w Polsce, co do zasady, nie praktykuje się wydawania statutów dla parafii (według stanu na dzień 5 lutego 2019 roku w Krajowym Rejestrze Sądowym zarejestrowana jest tylko jedna parafia rzymskokatolicka jako organizacja pożytku publicznego), w związku z czym okoliczność ta stanowi przesłankę przesądzającą o braku możliwości zatrudniania wolontariuszy. Wobec powyższego, aby parafia mogła korzystać z pracy wolontariuszy, konieczne jest uchwalenie statutu przewidującego obok działalności duszpasterskiej również działalność pożytku publicznego. Jednakże wykluczenie przeszkody natury podmiotowej związanej ze statusem parafii jako podmiotu mogącego korzystać z pracy wolontariuszy nie eliminuje przeszkód związanych z istotą wolontariatu sprowadzającą się do nieodpłatnej pracy wolontariusza. Wobec powyższego zatrudnianie przez parafie wolontariuszy do wykonywania regularnej pracy w kościele parafialnym na stanowisku organisty należy uznać jako sprzeczne z przepisami powszechnie obowiązującego prawa krajowego oraz normami prawa kanonicznego.
Legitymacja czynna domu zakonnego Ojców Augustianów w Krakowie w postępowaniu regulacyjnym
Authors: Walencik Dariusz
Published: April 2021

Składając wniosek, a następnie pozew w trybie przepisów art. 61 ust. 1 i art. 64 ust. 2 ustawy o stosunku państwa do Kościoła katolickiego w Rzeczypospolitej Polskiej kościelna osoba prawna musi wykazać swoją legitymację czynną do złożenia wniosku (pozwu), jego popierania oraz nabycia prawa własności. Musi zatem wykazać, że jest tą kościelną osobą prawną, która została pozbawiona własności nieruchomości wskutek jej upaństwowienia (tożsamość podmiotów), lub że jest następcą prawnym tej osoby. Wystąpienie z roszczeniem o przywrócenie własności nieruchomości upaństwowionej nie jest uzależnione od tego, czy nieruchomość ta uprzednio stanowiła własność tej osoby prawnej. Może bowiem zachodzić zarówno następstwo prawne w ścisłym tego słowa znaczeniu, jak i określone przepisami ustawy o stosunku państwa do Kościoła katolickiego w Rzeczypospolitej Polskiej uprawnienie do przywrócenia własności nieruchomości, należącej uprzednio do osoby prawnej tego Kościoła (następstwo sensu largo). Tożsamość lub następstwo prawne kościelnych osób prawnych wymagają wskazania podstawy prawnej nie tylko w prawie kanonicznym, lecz również w prawie polskim. W tym celu należy dokonać zarówno wykładni przepisów prawa materialnego, jak i procesowego. Nie ulega jednak wątpliwości, że w obowiązujących po jednostronnym wypowiedzeniu konkordatu z 1925 roku aż do 23 maja 1989 roku przepisach prawa polskiego takiej normy prawnej nie było, ponieważ ówczesny ustawodawca uchylał się od jej uchwalenia, mimo obowiązywania przepisu Konstytucji PRL w tym zakresie. Kwestie te zostały szczegółowo omówione w artykule na przykładzie nacjonalizacji i rewindykacji nieruchomości domu zakonnego Ojców Augustianów w Krakowie.
IV МЕЖДУНАРОДНЫЙ КОНГРЕСС, ПОСВЯЩЕННЫЙ А. Ф. САМОЙЛОВУ “ФУНДАМЕНТАЛЬНАЯ И КЛИНИЧЕСКАЯ ЭЛЕКТРОФИЗИОЛОГИЯ. АКТУАЛЬНЫЕ ВОПРОСЫ АРИТМОЛОГИИ”
Authors: Editorial Article
Published: April 2021

IV МЕЖДУНАРОДНЫЙ КОНГРЕСС, ПОСВЯЩЕННЫЙ А. Ф. САМОЙЛОВУ “ФУНДАМЕНТАЛЬНАЯ И КЛИНИЧЕСКАЯ ЭЛЕКТРОФИЗИОЛОГИЯ. АКТУАЛЬНЫЕ ВОПРОСЫ АРИТМОЛОГИИ”

7-8 АПРЕЛЯ 2021, Г. КАЗАНЬ

К 155-ЛЕТИЮ А. Ф. САМОЙЛОВА

СБОРНИК ТЕЗИСОВ
Some Kind of Bond
Authors: Cavarzan Chiara
Published: April 2021

Some Kind Of Bond is a film about a cemetery: a quiet and lonely place filled with life and memories. We observe the casual and the diligent visitors; we talk with them about their thoughts on death, loss and grief.

Some of them decide to invite us to their homes and together we go on an emotional journey through different personal experiences: the loss of a child, a grandparent and a mother.
Project management methodology enhancement for the transport infrastructure facilities construction
Authors: Telyatnikova Natalia
Published: April 2021

The use of the current methodology of the systematic approach, which differs from the existing ones by the integration of methods for modeling multidirectional processes in construction, as a complex system, tested on the example of a bridge crossing, increases the efficiency of the project and determines the direction of rationalizing organizational and technological solutions. Currently, the most promising companies focus on customer satisfaction within a clearly defined deadline. Failing to complete the planned work on time is an important problem in the transport facilities construction business since it entails additional expenses, which accordingly reduces the organization’s profit. Today, it is important to use alternative methods and approaches that allow for more efficient and quality project management that take into account the real construction stages’ cost and duration.
The main study idea is to improve the process companies support to increase management efficiency indicators in the transport facilities construction. The research is based on a systematic approach and software applied to construction processes. Managerial ties combination with correctly selected and used resources, in the presence of innovative technologies, will allow achieving visible results in the implementation of projects.
Project management based on a systematic approach, using modern software, is recommended for implementation and use in construction organizations, as this allows you to optimize scheduling and increase economic performance, even in times of uncertainty; allows you to reduce the cost of the resources and, to reduce the construction time; take into account the risks of the project, as well as control and track the actual implementation of projects for the construction of transport infrastructure facilities.
Application of Spatial Modeling of Biophysical Variables in an Urbanized Area in the Amazon: The Case of the Metropolitan Area of Belém-Pará
Authors: Silva Madson Tavares , Margalho Eduardo da Silva , Serrão Edivaldo Afonso de Oliveira , Souza Amanda Cartaxo de , Soares Caroline de Sá , Santos Carlos Antonio Costa dos , Silva Bernardo Barbosa da
Published: April 2021

Abstract The type of land use and land cover plays a decisive role in land surface temperature (LST). As cities are composed of varied covers, including vegetation, built-up areas, buildings, roads and areas without vegetation, understanding LST patterns in complex urban spaces is becoming increasingly important. The present study investigated the relationship between LST and albedo, NDVI, NDWI, NDBI and NDBaI in the period between 1994 and 2017. Images from Thematic Mapper (TM) and Thermal Infrared Sensor (TIRS) onboard the Landsat 5 and 8 satellites, respectively, were used in the study. The images were processed, resampled (spatial resolution of 120 m) in the environment of the QGIS 3.0 software and, finally, centroids were extracted resulting in a total of 1252 points. A classical regression (CR) model was applied to the variables, followed by spatial autoregressive (SARM) and spatial error (SEM) models, and the results were compared using accuracy indices. The results showed that the highest correlation coefficient was found between albedo and NDBaI (r = 0.88). The relationship between albedo and LST (r = 0.7) was also positive and significant at р < 0.05. The global Moran's I index showed spatial dependence and non-stationarity of the LST (I = 0.44). The SEM presented the best accuracy metrics (AIC = 3307.15 and R2 = 0.65) for the metropolitan region of Belém, explaining considerably more variations in the relationship between explanatory factors and LST when compared to conventional CR models.
A democracia brasileira e seus inimigos
Authors: Santos Everton Rodrigo , Castro Henrique Carlos de O. de , Hoffmann Fábio
Published: April 2021

Resumo: O objetivo central deste artigo é demonstrar que a democracia inercial no Brasil tem buscado resolver seus impasses valendo-se do uso do hardball na política, uma espécie de aplicação radical da lei, à revelia das instituições democráticas, num contexto de judicialização da política e ascensão do populismo. O autoritarismo tem-se revestido de outras formas de atuação neste início de século. O trabalho aponta de forma preliminar para dois exemplos de hardball recentes: o uso de pedidos de impeachments na política brasileira para defenestrar os adversários políticos (pelo Legislativo), com êxito em contextos de crise econômica, e o protagonismo da Lava Jato (pelo Judiciário), no combate à corrupção num contexto crescente de insatisfação com a democracia e suas instituições. Para tanto, utilizamos, como base empírica deste trabalho, os bancos de dados do Instituto Brasileiro de Geografia e Estatística, Datafolha e Pesquisa Mundial de Valores (WVS).
Estado e classes sociais: uma imbricada e contraditória relação
Authors: Santos Liliam dos Reis Souza
Published: April 2021

Resumo: Este artigo analisa a relação Estado e classes sociais no capitalismo. Evidencia a natureza contraditória, relacional e de classe do Estado. Atrela as determinações da relação Estado-classes sociais à dinâmica produtiva capitalista, à dominação e à luta política. Apresenta também as ações desempenhadas pelo Estado na inter-relação com as classes sociais, com o objetivo de manter a dominação das classes subalternas e a hegemonia das classes dominantes.
América Latina: capital e devastação social
Authors: Silva José Fernando Siqueira da
Published: April 2021

Resumo: O artigo analisa a América Latina no atual estágio de acumulação capitalista. O faz a partir de uma abordagem socio-histórica que recupera componentes da crítica à economia-política de Marx, bem como observações de parte de sua tradição sobre o imperialismo, o colonialismo, a dependência, a revolução burguesa realizada pela via colonial, a modernização conservadora e o desenvolvimento desigual e combinado. Nisto, a composição das classes dominantes e dos Estados latino-americanos. O texto recupera a experiência latino-americana do autor e os estudos realizados em projetos de pesquisa por ele coordenados a partir de 2011 na área de Serviço Social.
Brasil: fascismo ou neoescravidão?
Authors: Cortizo María del Carmen , Ruviaro Débora
Published: April 2021

Resumo: O artigo tem por objetivo discutir a pertinência do conceito de “fascismo” em referência ao atual governo do Brasil. A reflexão segue o caminho teórico-metodológico que dois dos maiores intelectuais italianos de início do século XX propuseram nas suas respectivas análises sobre o fascismo, trata-se de Piero Gobetti e Antonio Gramsci, servindo também como referência os relatos de Norberto Bobbio sobre a sua experiência pessoal em relação a esse regime. A partir dessa porta de acesso à problemática, são apresentadas as ponderações sobre a possibilidade de denominar o atual governo e o Estado brasileiro como “fascistas”. A conclusão do estudo é que as atuais relações sociais no Brasil respondem ao desenvolvimento histórico de ininterrupta reprodução das relações de subordinação a partir da escravidão, e não a uma forma particular de fascismo ou de fascistização. Metodologicamente assume-se a perspectiva da “história integral”. Em termos das ferramentas para as análises, o estudo se vale de material bibliográfico.
Revolução burguesa dependente e contrarrevolução no Brasil
Authors: Evangelista Diogo Prado
Published: April 2021

Resumo: Neste artigo pretende-se expor o resultado da pesquisa acerca do processo de revolução burguesa no Brasil e sua consolidação a partir do golpe empresarial-militar de 1964. Dessa maneira, revolução e contrarrevolução tornam-se estrutural para as transformações capitalistas e as formas ideológicas e políticas de dominação burguesa no País. Esses aspectos contribuem para elucidar a particularidade da forma política de democracia burguesa, desmistificando os elementos construtivos de sua ampliação e aprofundamento jurídico-legal como meio de emancipação política da população trabalhadora.
Uma interpretação marxista sobre a infância e os abrigos
Authors: Lima Rodrigo Silva
Published: April 2021

Resumo: O objetivo desse artigo é contribuir com a produção do conhecimento na área da infância e da adolescência, a partir da produção marxiana e autores da tradição marxista. Observa-se a pouca incidência do marxismo nos estudos sobre a situação de vida crianças e adolescentes. Para além de abordagens individuais, considera-se o processo de institucionalização em abrigos uma resposta às expressões da questão social e não o descompasso das famílias da classe trabalhadora em suas funções protetivas. Essas instituições cumprem uma função na reprodução social, por meio da proteção e da coerção, assim como a preparação da mão de obra para uma inserção precarizada no mercado de trabalho, reproduzindo o ciclo de dependência institucional e a exploração.
A PRESENÇA DE ANTOLOGIAS NO ACERVO DO ENSINO MÉDIO DISTRIBUÍDO PELO PNBE
Authors: Morais Caroline de , Ramos Flávia Brocchetto
Published: April 2021

O presente artigo tem como objetivo central analisar a presença de obras antológicas selecionadas pelo PNBE (Programa Nacional Biblioteca da Escola) no acervo destinado ao Ensino Médio, na edição de 2013. O Programa é visto como uma política pública voltada para a educação literária que se preocupa com a formação leitora e com o acesso aos bens culturais. Para essa investigação com metodologia analítica, define-se como objeto de estudo o Acervo 3, da edição PNBE 2013, última do Programa a atender a etapa do Ensino Médio. No material investigado, separam-se as obras antológicas selecionadas mediante edital, considerando o todo de 60 obras literárias pertencentes ao acervo distribuído para as bibliotecas escolares públicas. Diante desse panorama, o presente estudo conclui que as antologias estão reconhecidas e obtêm espaço significativo no acervo em questão, prestigiando autores da Literatura Brasileira ao reunir textos já publicados em momentos anteriores ao da organização da obra antológica.
Four New Species of Asemeia (Polygalaceae) from Goiás State, Brazil
Authors: Mota Michelle , Barêa Pastore José Floriano
Published: April 2021

Abstract—Four new species of Asemeia (Polygalaceae) are here described, Asemeia aguiariana, A. campestris, A. eglandulosa, and A. subaphylla, which are endemic to savannas in central Brazil, in Goiás State. Detailed descriptions,
photographic plates illustrating the new species and comparing the floral morphology of allied species, a distribution map and an identification key are provided.
Anti Human CX3CR1 VHH Molecule Attenuates Venous Neointimal Hyperplasia of Arteriovenous Fistula in Mouse Model
Authors: Misra Sanjay , Kilari Sreenivasulu , Yang Binxia , Sharma Amit , Wu Chih-Cheng , Vazquez-Padron Roberto I. , Broadwater John
Published: April 2021

Significance Statement

Fractalkine receptor 1 (CX3CR1) mediates macrophage infiltration into the vasculature. In this study, we used humanized mice knocked in with the human CX3CR1 gene and inhibited CX3CR1 signaling using a variable domains of camelid heavy-chain-only molecule (BI 655088) to test the hypothesis that blockade of CX3CR1 results in less of the venous neointimal hyperplasia formation that is associated with arteriovenous fistula (AVF) failure. We also used human samples removed from failed AVFs combined with cell culture experiments. Our results demonstrate a novel role for CX3CR1 in reducing venous stenosis formation in AVFs.

Background

Fractalkine receptor 1 (CX3CR1) mediates macrophage infiltration and accumulation, causing venous neointimal hyperplasia (VNH)/venous stenosis (VS) in arteriovenous fistula (AVF). The effect of blocking CX3CR1 using an anti–human variable VHH molecule (hCX3CR1 VHH, BI 655088) on VNH/VS was determined using a humanized mouse in which the human CX3CR1 (hCX3CR1) gene was knocked in (KI).

Methods

Whole-transcriptomic RNA sequencing with bioinformatics analysis was used on human stenotic AVF samples, C57BL/6J, hCX3CR1 KI mice with AVF and CKD, and in in vitro experiments to identify the pathways involved in preventing VNH/VS formation after hCX3CR1 VHH administration.

Results

Accumulation of CX3CR1 and CD68 was significantly increased in stenotic human AVFs. In C57BL/6J mice with AVF, there was increased Cx3cr1, Cx3cl1, Cd68, and Tnf-α gene expression, and increased immunostaining of CX3CR1 and CD68. In hCX3CR1-KI mice treated with hCX3CR1 VHH molecule (KI-A), compared with vehicle controls (KI-V), there was increased lumen vessel area and patency, and decreased neointima in the AVF outflow veins. RNA-seq analysis identified TNF-α and NF-κB as potential targets of CX3CR1 inhibition. In KI-A–treated vessels compared with KI-V, there was decreased gene expression of Tnf-
α, Mcp-1, and Il-1
β; with reduction of Cx3cl1, NF-κB, and Cd68; decreased M1, Ly6C, smooth muscle cells, fibroblast-activated protein, fibronectin, and proliferation; and increased TUNEL and M2 staining. In cell culture, monocytes stimulated with PMA and treated with hCX3CR1 VHH had decreased TNF-
α, CD68, proliferation, and migration.

Conclusions

CX3CR1 blockade reduces VNH/VS formation by decreasing proinflammatory cues.
CTLA4Ig Gene Transfer Prolongs Survival and Induces Donor-Specific Tolerance in a Rat Renal Allograft
Authors: TOMASONI SUSANNA , AZZOLLINI NADIA , CASIRAGHI FEDERICA , CAPOGROSSI MAURIZIO C. , REMUZZI GIUSEPPE , BENIGNI ARIELA
Published: April 2021

Organ transplantation requires lifelong antirejection therapy, which carries the risk of infection and cancer. A revolutionary approach is to transduce the organ graft with immunomodulatory genes to render them tolerated with no need of systemic immunosuppression. Prolonged allograft survival was achieved by adenovirus-mediated transduction of the cold-preserved kidney with sequences encoding CTLA4Ig, a recombinant fusion protein that blocks T cell activation. Organ expression of the transgene was achieved associated with mild infiltration of mononuclear cells in the transfected kidney. Mixed lymphocyte reaction as well as the production of both Th1 and Th2 cytokines were reduced. Thus, the gene transfer technique to prolong graft survival is indeed effective and safe and can induce donor-specific unresponsiveness. Pending appropriate large animal testing, ex vivo genetic manipulation of the organ before surgery may hopefully represent a major step forward in human transplant medicine.
Just Advisory and Maximally Representative: A Conjoint Experiment on Non-Participants' Legitimacy Perceptions of Deliberative Forums
Authors: Goldberg Saskia
Published: April 2021

Citizen involvement in deliberative forums is frequently discussed with an eye to boosting the legitimacy of decision-making. However, this idea has been radically challenged by Cristina Lafont (2015, 2017, 2019), who argues that deliberative forums may decrease rather than increase legitimacy. Yet Lafont’s legitimacy challenge has been primarily discussed at a theoretical level without taking the perceptions of citizens into account. Referring to an explorative student conjoint experiment this article examines how non-participants assess deliberative forums. It focuses on different authorization mechanisms and a set of institutional design features and combines them with non-participants’ substantive considerations and their awareness of such forums. Empirical findings of the student sample confirm Lafont’s critique, as they suggest that respondents want the authority of deliberative forums to be clearly circumscribed and minimal but also maximally representative and inclusive. Moreover, legitimacy perceptions are closely tied to substantive considerations and awareness of such novel and unfamiliar institutions.
Od svijesti do ponašanja: individualna, socijalna i ekološka odgovornost slovenske mladeži
Authors: Golob Tea , Makarovič Matej
Published: April 2021

Individualization trends encouraging young people to focus on their achievements seem to contradict the need for socially and environmentally sustainable behavior, and this requires additional empirical testing. The purpose of this paper is to present and provide basic testing of an original model of responsible behavior. The model is inspired by the theory of planned behavior distinguishing between consciousness, intentions, and behavior. The presented model applies these to an individual as well as to social and environmental responsibility while taking into account the social, technological, and natural environments. The research is based on the presumption that it is crucial to connect the individual dimension of responsibility with the environmental and social dimensions to achieve environmental and social sustainability at the micro-level. Data for the preliminary testing of the model was collected from an online social survey among Slovenian youth and analyzed through partial correlations and path analysis. The results show that individual responsibility is strongly connected to social and environmental responsibilities, but only in terms of behavior, and not values and intentions. Responsibility is also strongly connected to the social and technological environment, especially to the ways how young people are using digital technology.
Znanje u funkciji transformacije društva prema ekonomiji smisla
Authors: Šundov Marko
Published: April 2021

Bit nove ekonomije leži u preobražavanju ekonomske misli iz egocentrične u ekocentričnu svijest. Znanje u takvom procesu nosi ključnu ulogu, a redefiniranje funkcije koju ono danas ima u modernim društvima neoliberalne ekonomske doktrine predstavlja temeljni preduvjet transformacije društva prema ekonomiji smisla. Svijest pojedinca stoga se odmiče od vrijednosti zajedničkog i usmjerava se k vrijednostima pojedinačnog, kao nečeg nužnog kako bi se ostvario u potpunosti. Individualizacija stoga postaje uporište i temeljni pokretač procesa proizvodnje znanja u modernim društvima. Ubrzavanje vremena determinirano samo jednim društvenim područjem djelovanja pojedinca (ekonomskim) direktno se odražava na strukturu i volumen znanja koje tokom svog života treba usvojiti. Ovim radom ukazuje se na povezanost vremena tj. komprimiranja vremena pojedinca sa strukturom i volumenom znanja koje proizvode pojedine dionice lanaca proizvodnje znanja. Znanje koje se nameće pojedincu determinirano je tržišnim zakonitostima i korporativnim vrijednostima koje nadilaze sve ostale društvene vrijednosti. Svi pokazatelji, od ekonomskih, klimatskih, energetskih i sl., ukazuju na neodrživost individualnog tipa svjesnosti te proces proizvodnje znanja orijentiranog isključivo pojedinačnim interesima. Stoga se nužnim nameće potreba uspostavljanja nove platforme za proizvodnju znanja koja za primarni cilj ima stvaranje društvenih skupina nositelja promjena prema ekonomiji smisla.
Primera cita de Psalidodon dissensus (Lucena & Thofehrn 2013) (Characiformes, Characidae) en tributarios de la cuenca del río Uruguay, Misiones, Argentina
Authors: Araya Patricia Raquel , Flores Silvia Alicia , Serrano Marcelo Javier , Barboza Adriana Griselda
Published: April 2021

Se realiza la primera cita de Psalidodon dissensus en cursos de agua de la provincia de Misiones, a partir de ejemplares provenientes del arroyo Yabotí, afluente del río Uruguay, inmerso en la Reserva de Biosfera Yabotí. Revalidado de la sinonimia del género Astyanax, Psalidodon incluye 21 nuevas combinaciones para la Argentina de la cuales siete están presentes en los sistemas fluviales de Misiones. La ictiofauna de la provincia, perteneciente a la Provincia Parano‐Platense, se caracteriza por la elevada diversidad y endemismo que la convierten en territorio de formidable valor biológico y de urgente necesidad de conservación.
Transboundary Hydrocarbon Resources: Political and Legal Mechanisms for Preventing International Conflicts
Authors: Vylegzhanin A. , Salygin V. , Krymskaya K.
Published: April 2021

Since hydrocarbon resources found close to the delimitation line between two or more states require special regulation due to its complex and sensitive nature, the states involved have to consider national legislation and applicable international instruments relating to transboundary exploitation, as well as interests of their oil and gas companies. However, when one state unilaterally explores or exploits the deposit from its side of the delimitation line, it ipso facto violates the rights of the other state, thus leading to a potential international conflict, that would take years to settle. The previously practiced method of seizing such deposits on the “first come – first take” basis is currently considered fraught with interstate conflicts. Moreover, this approach is, economically irrational and, without any doubt, bears a greater negative impact on the environment, thus making an agreed regime of transboundary subsoil use more viable. Often coastal states reach an agreement on transboundary activities, that calls for intergovernmental consultations to be held once a particularly transboundary deposit is discovered. It is usually followed by conclusion of contract between operating companies, that addresses all the technical issues of exploration and exploitation of specific field. The existing political and legal mechanisms of transboundary subsoil regulation prove to be successful, especially in previously disputed maritime areas. State practice demonstrates the tendency towards universal agreement-based exploration and exploitation of transboundary hydrocarbon resources. Applicable political and legal mechanisms will presumably evolve and differ from one another depending on the individual characteristics of oil and gas fields in question and areas where the deposits are located.
China and Japan in the Process of Financial Integration in Asia
Authors: Nozdrev S.
Published: April 2021

The article discusses the main areas and features of China and Japan participation in the process of financial integration. A comparative analysis of the possibilities of interaction with Asian countries in the credit and securities markets has been carried out. A special place is given to China and Japan activities in regional financial organizations and associations. It is argued that sphere of regional financial integration is one of the areas of economic cooperation between the two countries where along with the trends towards cooperation there is also a process of increasing competition. Improving the quality of bilateral economic ties between China and Japan and the establishment of multilateral cooperation is not accompanied by a general restructuring of competitive relations in the region. A number of areas of economic activity remain in the sphere of competition which continues to increase both at the state and corporations and banks levels. China uses innovative aid technologies to create the Asian Infrastructure Investment Bank, eliminate existing bottlenecks, and acquire strategic assets in the region. Japan, despite strained relations with a number of Asian countries, continues to integrate into the regional economy through a network of production and logistics chains and is still a major source of capital for many Asian countries. All this suggests that, despite China's undoubted economic and financial success, it needs time to secure its leadership in the region. At the same time, the further deterioration of trade and economic relations between China and the United States, the consequences of the coronavirus crisis push China to more cooperation with Japan in stock, banking and currency areas, through regional economic organizations, and further expansion of the use of local currencies, primarily yen and renminbi, instead of dollars for investment and expansion of multilateral settlement and payment transactions in the region.
What Is State Failure?
Authors: Shevsky D.
Published: April 2021

The article is devoted to an overview of state failure conceptualization. One of the most popular concepts was failed state after transformed in fragile state. These two concepts are based on weberian understanding of the state that is irrelevant from historical perspective. Also critics have denoted to political labeling, incorrectness and the lack of formalization of these concepts. Since these indices were built for practical purposes, a full­fledged theoretical foundation for the idea of state weakness was elaborated in great details in a concept of state capacity. This concept tries to surpass the narrow weberian understanding of the state and offers three dimensions of state capacity: fiscal­economic, administrative­bureaucratic and the control over violence. The drawback of this concept is an absence of the threshold to understand whether the state has experienced state failure or not. The most formalized approach to measure state failure is created within a concept of state collapse. This concept has common with the previous concept because bases on the same features (fiscal, administrative and military). Using this concept faces some difficulties because of different cases are the same according to this concept. Sociology offered a concept of state breakdown which has three points: fiscal crisis, elite conflict and mass mobilization. After analyzing both sociological and anthropological literature the author offers to add to these three criteria two additional: deligitimation (or change of self­description in the system) and territorial disintegration.
A Pedagogical Perspective: An Exploration into Feedback and Group Work
Authors: Williams Ryan Thomas
Published: April 2021

There is a large body of education literature that discusses group work and feedback in a pedagogical sense. This is predominantly a consequence of a high percent of the literature being substantially social constructivist driven. However, there is still a significant need for research in this area due to a) the ever-changing 21st century and b) the amount of unanswered questions for teachers and practitioners, such as: How does an educator assign group tasks that encourage involvement, independence, a fair share of labor and in line with the curriculum? This short paper explored feedback and group work in a secondary setting using the author’s teaching experience as reference points throughout. More specifically, the paper highlighted strategies such as Kagan have become very popular in mainstream education over the last 5 years. Upon evaluating Kagan strategies, it was discovered that there was a need for pre-teaching of the strategies for pupils.
Electrocardiography in post hemodialysed chronic kidney disease patients
Authors: Soren Jatin , Majhi Chakradhar , Patel Nayan K.
Published: April 2021

Background: Chronic kidney disease (CKD) is associated with higher risk of cardiovascular events and Electrocardiographic changes are common in CKD patients. Electrocardiography (ECG) is cheap and easily available investigation that could pick up abnormalities of heart. Our study focuses on electrocardiographic changes seen within 24 hours in post hemodialysis CKD patients.Methods: It is a cross sectional, observational study of 298 CKD patients who underwent hemodialysis at tertiary care facility of VIMSAR, Burla during the period between November 2018 to November 2020. 12 leads ECG of these patients were taken post hemodialysis and abnormalities were interpreted.Results: Total number of patients included in the study were 298 with mean age distribution of 47±8.4 years. Mean Serum urea level was 126 mg/dl. Creatinine levels ranged between 5-10 mg/dl. Left ventricular hypertrophy (LVH) and left atrial enlargement (LAE) were seen in 14.76% and 8.3% of patients respectively. Atrial fibrillation was present in 4.3% of patients. Left axis deviation (LAD 7%), right axis deviation (RAD 6%), atrial ectopics (2.6%) and tall T waves (7.3%) were the other ECG changes observed.Conclusions: ECG changes are common in CKD patients in post hemodialysis state, so it becomes important to monitor these changes in these patients for early detection of any cardiac abnormalities.
Demographic profile, staging and CA-125 levels in a patient with pelvic lesions of probable ovarian origin at presentation in a tertiary care hospital
Authors: Gupta Rajeev , Mahajan Shveta , Kaur Sharandeep , Bansal Ankush , Kumar Dinesh , Sodhi Jasneet Kaur
Published: April 2021

Background: In Indian women, ovarian cancer is one of the most commonly diagnosed cancer. We wanted to analyze the demographic profile, staging, and sensitivity and specificity of CA-125 levels in a patient with ovarian cancer in an indian scenario.Methods: A retrospective study was performed and information was collected from 250 patients who visited SGRD Hospital, Vallah, Amritsar from 1 April 2016 to 30 April 2020, with pelvic lesions of probable ovarian origin on demographic profile, the staging of the disease and CA-125 levels. Data was collected, analyzed, and presented in frequency tables and figures.Results: The study comprised of 250 patients. CA-125 was mainly used to investigate a wide range of signs and symptoms and few tests were for follow up or screening of ovarian cancer. In female patients having a CA-125 for very high suspicion of malignancy/ovarian cancer, only 90 (36%) of the abnormal results were caused by ovarian cancer. False-positive results were largely caused by other malignancies. The specificity of CA-125 for ovarian cancer increased with concentrations over 1000 kU/litre. Serous adenocarcinoma was found the most common malignant tumor type of the ovary (53%). In the demographic profile, ovarian cancer was found to be highest in the sikh religious group (75%) and prevalent in the middle socioeconomic status 32% (n=80).Conclusions: These results confirm the high false-positive rate and poor sensitivity and specificity associated with CA-125 and the most common tumor type. The substantial inappropriate usage of CA-125 has led to results that are useless to the clinician, have cost implications, and add to patient anxiety and clinical uncertainty.
Clinical profile and bacteriological eitiology in cases of acute exacerbation of COPD in a tertiary care: a tertiary care study
Authors: Neelamma K. A. Sahana , E. Dinesh Ragav
Published: April 2021

Background: Acute exacerbation a prominent feature of COPD, is a major entity altering the course of the disease. These exacerbations are by complex interactions between host, bacteria, viruses and environment. Many studies done earlier indicate bacteria being the major cause of these exacerbations. This study is hence done to determine the bacteriological profile, haematological profile severity and grade clinical signs and symptoms based of ‘Gold’ criteria.Methods: A cross sectional descriptive study, done on a total of 80 cases for a period of 18 months on patients admitted to Sathya Sai medical college with acute exacerbations of chronic obstructive pulmonary disease. Cases of acute exacerbation of COPD satisfying the eligibility criteria were included in the study. Clinical and microbiological parameters were noted with special preference to sputum culture and spirometry.Results: Bacteria was not present in 46 (57.5%) of the study population. Klebsiella pneumoniae was present in 12 cases (15.0%), pseudomonas aeruginosa in 6 (7.5%), staphylococcus aureus in 6 (7.5%), streptococcus pneumoniae in 5 (6.2%) and actinobacter in 5 (6.2%). 34 cases were sensitive to antibiotics (52.5%). Majority being sensitive to ceftriaxone, piperacillin and levofloxacillin.  43 cases belonged to ‘Gold’ criteria on spirometry. Hyper inflated lung, tubular heart was present in 39 (48.8%) cases. With normal chest X-ray findings in the rest.Conclusions: Bacteria causing exacerbations is different in India as compared to other studies from different countries. Klebsiella pneumonia being most common organism followed by Pseudomonas aeruginosa, Staphylococcus aureus,Streptococcus pneumoniae and actinobacter. AECOPD patients with bacteria showed sensitivity to ceftriaxone, piperacillin and levofloxacillin. Hence, these etiology with sensitivity pattern should be kept in mind for starting a patient on empirical antibiotic therapy.
Recurrent hepatic encephalopathy precipitated by urinary tract infection in patient with liver cirrhosis: a case report
Authors: Saraswati Seputra Desak Putu Gayatri , Pralambari Luh Putu Dea Sasmita , Suryana Ketut
Published: April 2021

Liver cirrhosis is a chronic liver injury marked by necro-inflammation and fibrogenesis. It is associated with several life-threatening complications. Hepatic encephalopathy remains to be one of the most debilitating complication of liver cirrhosis. The occurrence of hepatic encephalopathy may be directly related to endogenous worsening of liver function or occurs in the presence of specific precipitating factor. Infection such as urinary tract infection is a common precipitant of hepatic encephalopathy. We present a case of 66 year old female with recurrent hepatic encephalopathy in hepatitis B-related liver cirrhosis precipitated by urinary tract infection. Rapid and precise recognition of precipitating factor in hepatic encephalopathy is very substantial for implementation of preventive measures and optimal treatment plan in order to achieve better outcomes in liver cirrhosis patient.
Induced mutations in crop plants at Instituto de Genética "Ewald A. Favret": mutants of scientific and/or agronomic interest: Induced mutations in crop plants at Instituto de Genética "Ewald A. Favret"
Authors: Landau Alejandra
Published: April 2021

The use of induced mutations techniques in crop plants at Instituto de Genética "Ewald A. Favret" (IGEAF) INTA, started in 1949, with the pioneer work of Ewald Favret, who studied the effects of physical and chemical mutagens on barley (Hordeum vulgare) and wheat (Triticum aestivum). IGEAF contributed with several novel results about the effects of important chemical mutagens such as ethyl methane sulfonate (EMS) and sodium azide, and their interactions with X-rays, on barley and wheat. During several decades, a good deal of the research was directed to study the relationship between the different effects of mutagenic treatments on the M1 and subsequent generations, and its implications for efficient selection of induced mutants. Many original barley and wheat mutants have been isolated at IGEAF, which early on contributed to elucidate the genetic basis of characters like the hormonal control of growth, the grain protein content and diseases reactions. Besides, several other novel mutants were isolated and characterized including genetically unstable mutants, which are able to originate new heritable variability. One of these mutants is the barley chloroplast mutator (cpm) from which some interesting mutants have been isolated. Moreover, a high throughput strategy for the screening of plastome mutants originated by the cpm was developed (cpTILLING) that allowed the detection of 61 different mutational events, showing the cpm as an extraordinary source of plastome mutants. On the other hand, protocols for direct selection of wheat mutants tolerant to drought were developed and promising advanced lines are at present investigated. Furthermore, a mutant allele of the AHAS (acetolactate synthase) gene in wheat conferring imidazolinones herbicides tolerance, was isolated. The incorporation of this allele to other genetic backgrounds showed increased levels of tolerance, which in one family were observed in association with increased Fusarium tolerance. In addition to the work done in barley and wheat, interactions with several breeding programs in other crops were carried out. Finally, some commercial achievements of INTA obtained by using induced mutations techniques are briefly described; being the most important the case of the INTA rice (Oryza sativa) breeding program for developing imidazolinones tolerant commercial varieties that in recent years covered 70% of the irrigated rice area in Latin America.