bluuebunny/crossref_metadata_2025 huggingface dataset:
Physical Properties of Peanut and Soy Protein-Based Emulsion Gels Induced by Various Coagulants
Authors: Zhang Shaobing , Jiang Yushan , Zhang Shuyan , Chen Lin
Published: January 2022

Emulsions of peanut and soy proteins, including their major components (arachin, conarachin, glycinin and β−conglycinin), were prepared by ultrasonication (300 W, 20 min) at a constant protein concentration (4%, w/v) and oil fraction (30%, v/v). These emulsions were then induced by CaCl2, transglutaminase (TGase) and glucono-δ-lactone (GDL) to form emulsion gels. The optimum coagulant concentrations were obtained for peanut and soy protein-stabilized emulsion gels, such as CaCl2 (0.15 and 0.25 g/dL, respectively), TGase (25 U/mL) and GDL (0.3% and 0.5%, w/v, respectively). For the CaCl2-induced emulsion gels, the hardness of the β−conglycinin gel was the highest, whereas that of the conarachin gel was the lowest. However, when TGase and GDL were used as coagulants, the strength of the conarachin emulsion gel was the best. For the GDL-induced emulsion gels, microstructural analysis indicated that the conarachin gel showed more homogeneous and compact structures. The gelation kinetics showed that the storage modulus (G′) of all the GDL-induced emulsions increased sharply except for the arachin-stabilized emulsion. The interactive force nature varied between conarachin and arachin emulsion gels. This work reveals that peanut conarachin could be used as a good protein source to produce emulsion gels when suitable coagulants are selected.
The Role of the Disrupted Podosome Adaptor Protein (SH3PXD2B) in Frank–Ter Haar Syndrome
Authors: Massadeh Salam , Alhabshan Fahad , AlSudairi Hadeel N. , Alkwai Sarah , Alsuwailm Moneera , Kabbani Mohamed S. , Chaikhouni Farah , Alaamery Manal
Published: January 2022

Frank–Ter Haar syndrome (FTHS), sometimes referred to as Ter Haar syndrome, is a rare hereditary disorder that manifests in skeletal, cardiac, and ocular anomalies, including hypertelorism, glaucoma, prominent eyes, and facial abnormalities. In this study, we performed whole-exome sequencing (WES) to identify the genetic component responsible for the phenotype of the index patient, a male infant born to a consanguineous family from Saudi Arabia. The analysis revealed a homozygous missense variant, c.280C>G, in the SH3PXD2B gene, which cosegregates with the familial phenotype with a plausible autosomal-recessive mode of inheritance, indicating a potential disease-causing association. The SH3PXD2B gene encodes a TKS4 podosome adaptor protein that regulates the epidermal growth factor signaling pathway. This study validates the critical function of the TKS4 podosome protein by suggesting a common mechanism underlying the pathogenesis of FTHS.
Effect of Face Masks on Blood Saturation, Heart Rate, and Well-Being Indicators in Health Care Providers Working in Specialized COVID-19 Center
Authors: Wojtasz Izabela , Cofta Szczepan , Czudaj Paweł , Jaracz Krystyna , Kaźmierski Radosław
Published: January 2022

This study aims to investigate whether wearing face masks (filtering facepieces, FFP class 2) with personal protective equipment (FPP2/PPE), while working a 12-h shift in a COVID-19 referral center, affects the blood saturation, heart rate (HR), and well-being of health care providers (HCPs). The study included a group of 37 HCPs. To perform continuous recordings of the SpO2 and heart rate (HR) in real time, we used a Nellcor PM10N (Covidien, Mansfield, MA, USA) portable monitoring system. SpO2, HR, and HCP well-being scales were measured during two 3-h shifts, while HCPs worked during a 12-h period. Additionally, each subject completed a questionnaire concerning their well-being. The difference in the SpO2 level between the 1st and 2nd working shifts while wearing an FFP2/PPE was small, with a median decrease in SpO2 of −1%. The scales of the well-being indicators increased within the shift. They were mainly fatigue and thirst with median scores of 2 out of 6 (range 0–4). We assume that during a 12-h period, a work scheme that consists of a 3-h shift in FFP2/PPE and a 3-h rest period (working without FPP2/PPE) is a reliable and safe solution for HCPs working in specialized COVID-19 referral hospitals.
Bridging the Knowledge Gap for Pressure Injury Management in Nursing Homes
Authors: Lee Ye-Na , Kwon Dai-Young , Chang Sung-Ok
Published: January 2022

Background: Pressure injuries in nursing homes remain a consistent problem. Unfortunately, despite the variety of pressure injury education offered in nursing homes, the knowledge learned cannot be applied in practice, and as a result, the prevalence and incidence of such injuries are consistently high. This study aimed to address those gaps by analyzing the nursing competency for pressure injury management and implementing pressure injury education programs in nursing homes. Methods: Two phases were conducted based on the action cycle in the knowledge to action model. During the first phase, a framework was constructed by analyzing nursing experience. The second phase consisted of the implementation and monitoring of the program to evaluate the effects of the framework. Results: The main results for nursing competencies for pressure injury management in nursing homes are integrated thinking, understanding in an environmental context, interpersonal relationships for efficient decision making, and meeting any challenges to professional development. The results concerning the program’s effects showed significant differences in the participants’ knowledge, attitude, stage discrimination ability, and clinical management judgment ability. Conclusion: The educational framework and program derived from this study are expected to improve nurses’ pressure injury management competency in nursing homes and to contribute to effective pressure injury management and quality of life for residents in nursing homes.
Interparental Conflict and Early Adulthood Depression: Maternal Care and Psychological Needs Satisfaction as Mediators
Authors: Zhen Shuangju , Liu Jinjin , Qiu Boyu , Fu Lianying , Hu Jianping , Su Binyuan
Published: January 2022

Previous research has identified exposure to interparental conflict (IPC) in childhood as a risk factor for young adults’ depression. However, there is still a lack of understanding of the underlying mediating mechanisms of this association. Driven by the spillover hypothesis, the present study investigated whether maternal antipathy and neglect, and in turn unmet psychological needs, mediated the relation between IPC and early adulthood depression in a sample of 347 undergraduate students (M = 23.27 years; SD = 0.86; 57.05% women) in China. The participants completed self-report measures of IPC, maternal care, satisfaction of basic psychological needs, and depression. Structural equation modeling revealed that: (a) IPC was positively associated with early adulthood depression; (b) this association was sequentially mediated by inadequate maternal care (i.e., antipathy and neglect) and by unsatisfied psychological needs. These findings suggest that efforts to prevent depression should focus on reducing not only IPC, but also inadequate maternal care and unmet psychological needs.
Synthesis and Characterization of High-Purity Mesoporous Alumina with Excellent Adsorption Capacity for Congo Red
Authors: Li Zhonglin , Wang Ding , Lv Fengcheng , Chen Junxue , Wu Chengzhi , Li Yuping , Shen Jialong , Li Yibing
Published: January 2022

We explore a more concise process for the preparation of high-purity alumina and to address the problem of some conventional micro- and nano-adsorbents having difficulty in exposing their adsorption sites to target pollutants in solution due to the heavy aggregation of the adsorbent, which confers poor adsorption properties. The methods of using gamma-phase high-purity mesoporous alumina (HPMA), with its excellent adsorption properties and high adsorption rates of Congo Red, and of using lower-cost industrial aluminum hydroxide by direct aging and ammonium salt substitution were successfully employed. The results showed that the purity of HPMA was as high as 99.9661% and the total removal rate of impurities was 98.87%, a consequence of achieving a large specific surface area of 312.43 m2 g−1, a pore volume of 0.55 cm3 g−1, and an average pore diameter of 3.8 nm. The adsorption process was carried out at 25 °C, the concentration of Congo Red (CR) dye was fixed at 250 mg L−1 and the amount of adsorbent used was 100 mg. The HPMA sample exhibited an extremely fast adsorption rate in the first 10 min, with adsorption amounts up to 476.34 mg g−1 and adsorption efficiencies of 96.27%. The adsorption equilibrium was reached in about 60 min, at which time the adsorbed amount was 492.19 mg g−1 and the dye removal rate was as high as 98.44%. One-hundred milligrams of adsorbent were weighed and dispersed in 200-mL CR solutions with mass concentrations ranging from 50–1750 mg L−1 to study the adsorption isotherms. This revealed that the saturation adsorption capacity of the produced HPMA was 1984.64 mg g−1. Furthermore, the process of adsorbing Congo Red in the synthesized product was consistent with a pseudo-second order model and the Langmiur model. It is expected that this method of producing HPMA will provide a productive, easy and efficient means of treating toxic dyes in industrial wastewater.
Design on Intelligent Feature Graphics Based on Convolution Operation
Authors: Li Ying , Tang Ye
Published: January 2022

With the development and application of artificial intelligence, the technical methods of intelligent image processing and graphic design need to be explored to realize the intelligent graphic design based on traditional graphics such as pottery engraving graphics. An optimized method is aimed to be explored to extract the image features from traditional engraving graphics on historical relics and apply them into intelligent graphic design. For this purpose, an image feature extracted model based on convolution operation is proposed. Parametric test and effectiveness research are conducted to evaluate the performance of the proposed model. Theoretical and practical research shows that the image-extracted model has a significant effect on the extraction of image features from traditional engraving graphics because the image brightness processing greatly simplifies the process of image feature extraction, and the convolution operation improves the accuracy. Based on the brightness feature map output from the proposed model, the design algorithm of intelligent feature graphic is presented to create the feature graphics, which can be directly applied to design the intelligent graphical interface. Taking some pottery engraving graphics from the Neolithic Age as an example, we conduct the practice on image feature extraction and feature graphic design, the results of which further verify the effectiveness of the proposed method. This paper provides a theoretical basis for the application of traditional engraving graphics in intelligent graphical interface design for AI products such as smart tourism products, smart museums, and so on.
Stress-Induced Cardiomyopathy—Considerations for Diagnosis and Management during the COVID-19 Pandemic
Authors: Moady Gassan , Atar Shaul
Published: January 2022

The novel coronavirus disease 2019 (COVID-19) is associated with several cardiovascular manifestations including myocardial injury, myocarditis, arrhythmia, and pulmonary embolism. Rare cases of stress-induced cardiomyopathy, or takotsubo syndrome have also been reported during the acute infection, and secondary to stress following lockdown and self-isolation. Diagnosis in the setting of the acute infection is challenging since conventional imaging modalities such as transthoracic echocardiography and coronary angiography should be restricted to minimize physician-patient contact until the patients is tested negative for COVID-19. The use of point of care hand-held ultrasound is appropriate for this purpose. The overall course of the disease seems to be similar to takotsubo in the general population. Physicians should be familiar with the clinical presentation, possible complications, and management of takotsubo during COVID-19 outbreak. Here, we review the special considerations in the diagnosis and management of takotsubo syndrome during the current pandemic.
Numerical Investigation on the Effects of Impeller Structures in Hot Metal Desulfurization Processes by Mechanical Stirring
Authors: Wang Ruizhi , Jia Shuyuan , He Zhu
Published: January 2022

With the increasing demand for high-quality steel, the requirements for the efficiency and stability of deep desulfurization are increasing too. The Kanbara Reactor (KR) is widely accepted around the world because of its high efficiency and economy. In order to destroy the rigid motion of molten iron in this area, two kinds of blade structures are designed and compared with traditional blades. In this study, a three-dimensional transient coupling mathematical model was established by using volume of fluid (VOF) and discrete phase model (DPM) to simulate the KR desulfurization process. The turbulence intensity of the molten iron, main vortex size and desulfurizing agent (DA) particle distributions for the three impeller models were investigated in detail. Model results showed that the staggered blade structure may improve the desulfurization efficiency of the KR process, and the desulfurization rate increases from 95.7% to 97.1% when compared with ordinary blades. The main reason for this can be attributed to the enhanced turbulence intensity of the molten iron, larger main vortex size and more uniform DA particle distributions. Plant tests also showed that the desulfurizer consumption per 1 ppm sulfur for the staggered blades was reduced by approximately 8.6%.
Evaluation of the Pitting Corrosion of Modified Martensitic Stainless Steel in CO2 Environment Using Point Defect Model
Authors: Radwan Ahmed Bahgat , Moussa Abdraman M. , Al-Qahtani Noora H. , Case Raymundo , Castaneda Homero , Abdullah Aboubakr M. , El-Haddad Muhsen A. M. , Bhadra Jolly , Al-Thani Noora Jabor
Published: January 2022

Pitting corrosion is a significant concern for the broader application of stainless steel in modern industries in which metal and metal alloy are detached preferentially from susceptible parts on the surface, resulting in the creation of holes in passivated alloys that are exposed to an aqueous, neutral electrolyte containing corrosive species. Exposure of SS to brines leads to the localized loss of surface passivity and the onset of isolated pitting, which render the equipment or piping unfit for service. In the present study, the passive layer behavior and the pitting corrosion of the modified martensitic stainless steel (MMSS) were evaluated in a saturated CO2 environment (pH~5) with different NaCl concentrations and temperatures, using various electrochemical techniques. It was found that by increasing the temperature up to 60 °C, the corrosion resistance of the MMSS increased; however, the corrosion rate dramatically increased at 80 °C, indicating the destruction of the oxide layer. According to the point defect model (PDM) results, the calculated values of polarizability (α), metal cation diffusivity (D), and the rate of annihilation of cation vacancies (jm), reveal a strong dependence on the solution temperature.
A New Look at Novel Cardiovascular Risk Biomarkers: The Role of Atherogenic Lipoproteins and Innovative Antidiabetic Therapies
Authors: Vekic Jelena , Zeljkovic Aleksandra , Al Rasadi Khalid , Cesur Mustafa , Silva-Nunes José , Stoian Anca Pantea , Rizzo Manfredi
Published: January 2022

The presence of residual cardiovascular disease (CVD) risk is a current dilemma in clinical practice; indeed, despite optimal management and treatment, a considerable proportion of patients still undergo major CV events. Novel lipoprotein biomarkers are suggested as possible targets for improving the outcomes of patients at higher risk for CVD, and their impact on major CV events and mortality have previously been investigated. Innovative antidiabetic therapies have recently shown a significant reduction in atherogenic lipoproteins, beyond their effects on glucose parameters; it has also been suggested that such anti-atherogenic effect may represent a valuable mechanistic explanation for the cardiovascular benefit of, at least, some of the novel antidiabetic agents, such as glucagon-like peptide-1 receptor agonists. This emphasizes the need for further research in the field in order to clearly assess the effects of innovative treatments on different novel biomarkers, including atherogenic lipoproteins, such as small dense low-density lipoprotein (LDL), lipoprotein(a) (Lp(a)) and dysfunctional high-density lipoprotein (HDL). The current article discusses the clinical importance of novel lipid biomarkers for better management of patients in order to overcome residual cardiovascular risk.
Applications of Graphene-Based Materials in Sensors: A Review
Authors: Liu Jihong , Bao Siyu , Wang Xinzhe
Published: January 2022

With the research and the development of graphene-based materials, new sensors based on graphene compound materials are of great significance to scientific research and the consumer market. However, in the past ten years, due to the requirements of sensor accuracy, reliability, and durability, the development of new graphene sensors still faces many challenges in the future. Due to the special structure of graphene, the obtained characteristics can meet the requirements of high-performance sensors. Therefore, graphene materials have been applied in many innovative sensor materials in recent years. This paper introduces the important role and specific examples of sensors based on graphene and its base materials in biomedicine, photoelectrochemistry, flexible pressure, and other fields in recent years, and it puts forward the difficulties encountered in the application of graphene materials in sensors. Finally, the development direction of graphene sensors has been prospected. For the past two years of the COVID-19 epidemic, the detection of the virus sensor has been investigated. These new graphene sensors can complete signal detection based on accuracy and reliability, which provides a reference for researchers to select and manufacture sensor materials.
New Flexible Tactile Sensor Based on Electrical Impedance Tomography
Authors: Wu Haibin , Zheng Bingying , Wang Haomiao , Ye Jinhua
Published: January 2022

In order to obtain external information and ensure the security of human–computer interaction, a double sensitive layer structured tactile sensor was proposed in this paper. Based on the EIT (Electrical Impedance Tomography) method, the sensor converts the information from external collisions or contact into local conductivity changes, and realizes the detection of one or more contact points. These changes can be processed into an image containing positional and force information. The experiments were conducted on the actual sensor sample. The OpenCV toolkit was used to process the positional information of contact points. The distributional regularities of errors in positional detection were analyzed, and the accuracy of the positional detection was evaluated. The effectiveness, sensitivity, and contact area of the force detection were analyzed based on the result of the EIT calculations. Furthermore, multi-object tests of pressure were conducted. The results of the experiment indicated that the proposed sensor performed well in detecting the position and force of contact. It is suitable for human–robot interaction.
A MEMS Electrochemical Angular Accelerometer Leveraging Silicon-Based Three-Electrode Structure
Authors: Chen Mingwei , Zhong Anxiang , Lu Yulan , Chen Jian , Chen Deyong , Wang Junbo
Published: January 2022

This paper developed an electrochemical angular micro-accelerometer using a silicon-based three-electrode structure as a sensitive unit. Angular acceleration was translated to ion changes around sensitive microelectrodes, and the adoption of the silicon-based three-electrode structure increased the electrode area and the sensitivity of the device. Finite element simulation was conducted for geometry optimization where the anode length, the orifice diameter, and the orifice spacing of the sensitive unit were determined as 200 μm, 80 μm, and 500 μm, respectively. Microfabrication was conducted to manufacture the silicon-based three-electrode structure, which then was assembled to form the electrochemical angular micro-accelerometer, leveraging mechanical compression. Device characterization was conducted, where the sensitivity, bandwidth, and noise level were quantified as 290.193 V/(rad/s2) at 1 Hz, 0.01–2 Hz, and 1.78 × 10−8 (rad/s2)/Hz1/2 at 1 Hz, respectively. Due to the inclusion of the silicon-based three-electrode structure, compared with previously reported electrochemical angular accelerometers, the angular accelerometer developed in this article was featured with a higher sensitivity and a lower self-noise level. Therefore, it could be used for the measurement of low-frequency seismic rotation signals and played a role in the seismic design of building structures.
Fourier Transform Infrared (FTIR) Spectroscopy to Analyse Human Blood over the Last 20 Years: A Review towards Lab-on-a-Chip Devices
Authors: Fadlelmoula Ahmed , Pinho Diana , Carvalho Vitor Hugo , Catarino Susana O. , Minas Graça
Published: January 2022

Since microorganisms are evolving rapidly, there is a growing need for a new, fast, and precise technique to analyse blood samples and distinguish healthy from pathological samples. Fourier Transform Infrared (FTIR) spectroscopy can provide information related to the biochemical composition and how it changes when a pathological state arises. FTIR spectroscopy has undergone rapid development over the last decades with a promise of easier, faster, and more impartial diagnoses within the biomedical field. However, thus far only a limited number of studies have addressed the use of FTIR spectroscopy in this field. This paper describes the main concepts related to FTIR and presents the latest research focusing on FTIR spectroscopy technology and its integration in lab-on-a-chip devices and their applications in the biological field. This review presents the potential use of FTIR to distinguish between healthy and pathological samples, with examples of early cancer detection, human immunodeficiency virus (HIV) detection, and routine blood analysis, among others. Finally, the study also reflects on the features of FTIR technology that can be applied in a lab-on-a-chip format and further developed for small healthcare devices that can be used for point-of-care monitoring purposes. To the best of the authors’ knowledge, no other published study has reviewed these topics. Therefore, this analysis and its results will fill this research gap.
Influence of Current on Soil Corrosion of Galvanized Steel of Grounding Grids
Authors: Song Linbo , Zhang Cheng , Zhao Jing , Yang Rui , Yuan Yuan
Published: January 2022

Grounding grid materials are vulnerable to soil corrosion, which is detrimental to the safe operation of the grounding grids and even lead to serious accidents of power transmission. In this paper, galvanized steel was used as the typical grounding grid material which was buried in the soil and then electrified with AC and DC current for two weeks. The corroded samples under different current conditions were characterized and compared. The experimental results show that the corrosion degree of galvanized steel gradually aggravated with the increasing of the current, especially under DC current. Further, the mechanism of the influence of current on soil corrosion is explored. It is found that under the same magnitude of current, the corrosion degree of galvanized steel under DC current is greater than that under AC current.
All-In-Focus Polarimetric Imaging Based on an Integrated Plenoptic Camera with a Key Electrically Tunable LC Device
Authors: Chen Mingce , Li Zhexun , Ye Mao , Liu Taige , Hu Chai , Shi Jiashuo , Liu Kewei , Wang Zhe , Zhang Xinyu
Published: January 2022

In this paper, a prototyped plenoptic camera based on a key electrically tunable liquid-crystal (LC) device for all-in-focus polarimetric imaging is proposed. By using computer numerical control machining and 3D printing, the proposed imaging architecture can be integrated into a hand-held prototyped plenoptic camera so as to greatly improve the applicability for outdoor imaging measurements. Compared with previous square-period liquid-crystal microlens arrays (LCMLA), the utilized hexagonal-period LCMLA has remarkably increased the light utilization rate by ~15%. Experiments demonstrate that the proposed imaging approach can simultaneously realize both the plenoptic and polarimetric imaging without any macroscopic moving parts. With the depth-based rendering method, both the all-in-focus images and the all-in-focus degree of linear polarization (DoLP) images can be obtained efficiently. Due to the large depth-of-field advantage of plenoptic cameras, the proposed camera enables polarimetric imaging in a larger depth range than conventional 2D polarimetric cameras. Currently, the raw light field images with three polarization states including I0 and I60 and I120 can be captured by the proposed imaging architecture, with a switching time of several tens of milliseconds. Some local patterns which are selected as interested target features can be effectively suppressed or obviously enhanced by switching the polarization state mentioned. According to experiments, the visibility in scattering medium can also be apparently improved. It can be expected that the proposed polarimetric imaging approach will exhibit an excellent development potential.
Validation of Two Commercial Multiplex Real-Time PCR Assays for Detection of SARS-CoV-2 in Stool Donors for Fecal Microbiota Transplantation
Authors: Di Pilato Vincenzo , Morecchiato Fabio , Rizzato Cosmeri , Quaranta Gianluca , Fais Roberta , Gandolfo Claudia , Antonelli Alberto , Cusi Maria Grazia , Pistello Mauro , Rossolini Gian Maria , Sanguinetti Maurizio , Lupetti Antonella , Masucci Luca
Published: January 2022

Recurrent infection by Clostridioides difficile has recently been treated by fecal microbiota transplantation (FMT). As viable SARS-CoV-2 was recovered from stool of asymptomatic individuals, the FMT procedure could be a potential risk of SARS-CoV-2 transmission, thus underlying the need to reliably detect SARS-CoV-2 in stool. Here, we performed a multicentric study to explore performances of two commercially available assays for detection of SARS-CoV-2 RNA in stool of potential FMT donors. In three hospitals, 180 stool samples were spiked with serial 10-fold dilutions of a SARS-CoV-2 inactivated lysate to evaluate the Seegene Allplex™ SARS-CoV-2 (SC2) and SARS-CoV-2/FluA/FluB/RSV (SC2FABR) Assays for the detection of viral RNA in stool of FMT donors. The results revealed that both assays detected down to 2 TCID50/mL with comparable limit of detection values, SC2 showing more consistent target positivity rate than SC2FABR. Beyond high amplification efficiency, correlation between CT values and log concentrations of inactivated viral lysates showed R2 values ranging from 0.88 to 0.90 and from 0.87 to 0.91 for the SC2 and SC2FABR assay, respectively. The present results demonstrate that both methods are highly reproducible, sensitive, and accurate for SARS-CoV-2 RNA detection in stool, suggesting a potential use in FMT-donor screening.
The Lactobacillus as a Probiotic: Focusing on Liver Diseases
Authors: Jeong Jin-Ju , Park Hee Jin , Cha Min Gi , Park Eunju , Won Sung-Min , Ganesan Raja , Gupta Haripriya , Gebru Yoseph Asmelash , Sharma Satya Priya , Lee Su Been , Kwon Goo Hyun , Jeong Min Kyo , Min Byeong Hyun , Hyun Ji Ye , Eom Jung A , Yoon Sang Jun , Choi Mi Ran , Kim Dong Joon , Suk Ki Tae
Published: January 2022

Over the past decade, scientific evidence for the properties, functions, and beneficial effects of probiotics for humans has continued to accumulate. Interest in the use of probiotics for humans has increased tremendously. Among various microorganisms, probiotics using bacteria have been widely studied and commercialized, and, among them, Lactobacillus is representative. This genus contains about 300 species of bacteria (recently differentiated into 23 genera) and countless strains have been reported. They improved a wide range of diseases including liver disease, gastrointestinal diseases, respiratory diseases, and autoimmune diseases. Here, we intend to discuss in depth the genus Lactobacillus as a representative probiotic for chronic liver diseases.
The Identification of Multidrug-Resistant Microorganisms including Bergeyella zoohelcum Acquired from the Skin/Prosthetic Interface of Amputees and Their Susceptibility to Medihoney™ and Garlic Extract (Allicin)
Authors: Harsent Ruby , Macleod Joshua , Rowlands Richard S. , Smith Paul M. , Rushmere Neil , Blaxland James
Published: January 2022

Users of prosthetic devices face the accumulation of potentially drug-resistant pathogenic bacteria on the skin/prosthesis interface. In this study, we took surface swabs of the skin/prosthesis interface of eleven disabled athletes to identify microorganisms present. In addition to determining their antimicrobial resistance profile, we assessed their sensitivity to Manuka honey and Garlic extract (allicin). Eleven volunteers were directed to swab the skin at the skin/prosthesis interface. After initial isolation of microorganisms, we employed the following general microbiological methods: Gram stain, Catalase test, Oxidase test, lactose fermenting capability, haemolytic capability, Staphaurex, mannitol fermenting capability, Streptex; API Staph, 20E, Candida, and BBL crystal identification system tests. Once identified, isolates were analysed for their sensitivity to penicillin, erythromycin, ampicillin, vancomycin, ceftazidime, ciprofloxacin, gentamicin, and colistin-sulphate. Isolates were also analysed for their sensitivity to allicin (Garlic Extract (GE)) and Manuka honey (Medihoney™) (MH). Eleven isolates were identified: Bacillus cereus, Staphylococcus haemolyticus, Staphylococcus aureus, Micrococcus luteus, Pseudomonas oryzihabitans, Micrococcus spp., Bacillus subtilis, Group D Streptococcus, Pantoea spp., Enterobacter cloacae, and Bergeyella zoohelcum. All isolates were resistant to 1 unit of penicillin and 10 μg of ampicillin. Bergeyella zoohelcum was observed to have the widest range of resistance with observed resistance against five of the eight antimicrobials employed in this study. This study highlights the prevalence of uncommon drug-resistant microorganisms on the skin within a vulnerable population, highlighting the potential for MH or GE intervention.
Phytoremediator Potential of Ipomea asarifolia in Gold Mine Waste Treated with Iron Impregnated Biochar
Authors: Costa Hercília Samara Cardoso , de Souza Edna Santos , Dias Yan Nunes , Melo Leônidas Carrijo Azevedo , Fernandes Antonio Rodrigues
Published: January 2022

Growing environmental pollution in recent decades has been generating potentially toxic elements (PTE) which pose an ongoing threat to terrestrial and aquatic ecosystems and human health, especially in mining areas. Biochar and PTE-tolerant species have been used in soil remediation as they are environmentally friendly alternatives. This study aimed to assess the influence of açaí seed biochar (Euterpe oleracea Mart), impregnated with iron (BFe) or not (BC), on the bioavailability of PTEs, in a multi-contaminated soil from a gold (Au) mining area in the Amazon, using Ipomea asarifolia as a plant test since it was naturally growing on the tailings. BC increased the soil pH while BFe reduced. Biochars increased PTEs in the oxidizable fraction (linked to soil organic matter). The use of BC and BFe improved the immobilization of PTEs and BC increased arsenic (As) in the easily soluble fraction in the soil. Moreover, plants grown with biochars showed lower dry matter yield, higher concentrations of PTEs and lower nutrient content than the control treatment. According to the phytoextraction and translocation factors, Ipomea asarifolia can be classified as a species with potential for phytostabilization of Zn and tolerant to other PTEs, mainly As.
Numerical Simulation Study on the Multi-Physical Field Response to Underground Coal and Gas Outburst under High Geo-Stress Conditions
Authors: Zhao Bo , Wen Guangcai , Nian Jun , Ma Qianwei , Fan Chaojun , Lv Xiaobo , Deng Chunsheng
Published: January 2022

Based on thermal–fluid–solid coupling law in coal and gas outburst, a multi-physical field numerical analysis model is built for the whole outburst process. The response laws of stress, gas pressure, temperature, and seepage in different areas and different time nodes around coal and rock mass in the coal and gas outburst under high stress condition are discussed. Research results show: Firstly, the stress response law of the coal and rock mass around the burst hole is initial vibration–sudden attenuation–late stability. Secondly, the gas pressure response law in different areas is that the gas pressure response rate decreases gradually with the increase of the distance from the outburst. Thirdly, the adsorbed gas contained in the broken coal near the outburst port is desorbed rapidly and expands to do work, and the temperature changes dramatically after outburst occurs. In contrast, with the increase of stress, the proportion of elastic potential in total coal and gas outburst energy increases, and the proportion of elastic potential is positively correlated with stress. The critical gas pressure under the energy condition of coal and gas outburst decreases with the increase of stress. It illustrates that the lower gas pressure can also meet the energy condition of coal and gas outburst under high stress.
Bioactive-Based Cosmeceuticals: An Update on Emerging Trends
Authors: Goyal Anju , Sharma Aditya , Kaur Jasanpreet , Kumari Sapna , Garg Madhukar , Sindhu Rakesh K. , Rahman Md. Habibur , Akhtar Muhammad Furqan , Tagde Priti , Najda Agnieszka , Banach-Albińska Barbara , Masternak Katarzyna , Alanazi Ibtesam S. , Mohamed Hanan R. H. , El-kott Attalla F. , Shah Muddaser , Germoush Mousa O. , Al-malky Hamdan S. , Abukhuwayjah Salman H. , Altyar Ahmed E. , Bungau Simona G. , Abdel-Daim Mohamed M.
Published: January 2022

Cosmetic-containing herbals are a cosmetic that has or is claimed to have medicinal properties, with bioactive ingredients purported to have medical benefits. There are no legal requirements to prove that these products live up to their claims. The name is a combination of “cosmetics” and “pharmaceuticals”. “Nutricosmetics” are related dietary supplements or food or beverage products with additives that are marketed as having medical benefits that affect appearance. Cosmetic-containing herbals are topical cosmetic–pharmaceutical hybrids intended to enhance the health and beauty of the skin. Cosmetic-containing herbals improve appearance by delivering essential nutrients to the skin. Several herbal products, such as cosmetic-containing herbals, are available. The present review highlights the use of natural products in cosmetic-containing herbals, as natural products have many curative effects as well as healing effects on skin and hair growth with minimal to no side effects. A brief description is given on such plants, their used parts, active ingredients, and the therapeutic properties associated with them. Mainly, the utilization of phytoconstituents as cosmetic-containing herbals in the care of skin and hair, such as dryness of skin, acne, eczema, inflammation of the skin, aging, hair growth, and dandruff, along with natural ingredients, such as for hair colorant, are explained in detail in the present review.
Highly Sensitive Fingerprint Detection under UV Light on Non-Porous Surface Using Starch-Powder Based Luminol-Doped Carbon Dots (N-CDs) from Tender Coconut Water as a Green Carbon Source
Authors: Nugroho David , Keawprom Chayanee , Chanthai Saksit , Oh Won-Chun , Benchawattananon Rachadaporn
Published: January 2022

This study aims to synthesize carbon dots from a natural resource and will be used to detect a latent fingerprint on a non-porous surface. The carbon dots (CDs) were prepared by adding luminol to coconut water and ethanol via a hydrothermal method. Luminol enhances the chemiluminescence of the CDs, which show more distinct blue light under a UV lamp compared with bare CDs. To detect the latent fingerprint, luminol carbon dots (N-CDs) were combined with commercial starch and stirred at room temperature for 24 h. Their characteristics and optical properties were measured using EDX-SEM, HR-TEM, FTIR, XPS, UV–visible absorption, and fluorescence. In this research, it was found that the N-CDs had a d-spacing of 0.5 nm and a size of 12.9 nm. The N-CDs had a fluorescence intensity 551% higher than the standard normally used. N-CDs can be used to detect latent fingerprints on a non-porous surface and are easy to detect under a UV lamp at 395 nm. Therefore, luminol has a high potential to increase sensitive and stable traces of chemiluminescence from the green CDs for forensic latent fingerprint detection.
Combination of Polysaccharide Nanofibers Derived from Cellulose and Chitin Promotes the Adhesion, Migration and Proliferation of Mouse Fibroblast Cells
Authors: Noda Tomoka , Hatakeyama Mayumi , Kitaoka Takuya
Published: January 2022

Extracellular matrix (ECM) as a structural and biochemical scaffold to surrounding cells plays significant roles in cell adhesion, migration, proliferation and differentiation. Herein, we show the novel combination of TEMPO-oxidized cellulose nanofiber (TOCNF) and surface-N-deacetylated chitin nanofiber (SDCtNF), respectively, having carboxylate and amine groups on each crystalline surface, for mouse fibroblast cell culture. The TOCNF/SDCtNF composite scaffolds demonstrated characteristic cellular behavior, strongly depending on the molar ratios of carboxylates and amines of polysaccharide NFs. Pure TOCNF substrate exhibited good cell attachment, although intact carboxylate-free CNF made no contribution to cell adhesion. By contrast, pure SDCtNF induced crucial cell aggregation to form spheroids; nevertheless, the combination of TOCNF and SDCtNF enhanced cell attachment and subsequent proliferation. Molecular blend of carboxymethylcellulose and acid-soluble chitosan made nearly no contribution to cell culture behavior. The wound healing assay revealed that the polysaccharide combination markedly promoted skin repair for wound healing. Both of TOCNF and SDCtNF possessed rigid nanofiber nanoarchitectures with native crystalline forms and regularly-repeated functional groups, of which such structural characteristics would provide a potential for developing cell culture scaffolds having ECM functions, possibly promoting good cellular adhesion, migration and growth in the designated cellular microenvironments.
Improved Melting of Latent Heat Storage Using Fin Arrays with Non-Uniform Dimensions and Distinct Patterns
Authors: Najim Farqad T. , Mohammed Hayder I. , Al-Najjar Hussein M. Taqi , Thangavelu Lakshmi , Mahmoud Mustafa Z. , Mahdi Jasim M. , Tiji Mohammadreza Ebrahimnataj , Yaïci Wahiba , Talebizadehsardari Pouyan
Published: January 2022

Employing phase-change materials (PCM) is considered a very efficient and cost-effective option for addressing the mismatch between the energy supply and the demand. The high storage density, little temperature degradation, and ease of material processing register the PCM as a key candidate for the thermal energy storage system. However, the sluggish response rates during their melting and solidification processes limit their applications and consequently require the inclusion of heat transfer enhancers. This research aims to investigate the potential enhancement of circular fins on intensifying the PCM thermal response in a vertical triple-tube casing. Fin arrays of non-uniform dimensions and distinct distribution patterns were designed and investigated to determine the impact of modifying the fin geometric characteristics and distribution patterns in various spatial zones of the heat exchanger. Parametric analysis on the various fin structures under consideration was carried out to determine the most optimal fin structure from the perspective of the transient melting evolution and heat storage rates while maintaining the same design limitations of fin material and volume usage. The results revealed that changing the fin dimensions with the heat-flow direction results in a faster charging rate, a higher storage rate, and a more uniform temperature distribution when compared to a uniform fin size. The time required to fully charge the storage system (fully melting of the PCM) was found to be reduced by up to 10.4%, and the heat storage rate can be improved by up to 9.3% compared to the reference case of uniform fin sizes within the same fin volume limitations.
Mechanical and Shape Memory Properties of Electrospun Polyurethane with Thiol-Ene Crosslinking
Authors: Briggs Sam , Herting Scott , Fletcher Grace , Gruenbaum Rachel , Maitland Duncan J.
Published: January 2022

The ability to treat complex medical issues often requires dynamic and versatile materials. Electrospinning is a fabrication technique which produces nano-/microfibers that can mimic the extracellular matrix of many biological tissues while shape memory polymers allow for geometric changes in devices upon implantation. Here, we present the fabrication of electrospun polyurethane which exhibits the shape memory effect. To improve the mechanical and shape memory properties of this system, we incorporate vinyl side chains in the polymer backbone which enable crosslinking via thiol-ene click chemistry post fabrication. We also discuss a novel technique to improve photoinitiated crosslinking for electrospun materials. A material with these properties is potentially beneficial for various medical applications, such as vascular anastomosis, and the characterization of this material will be valuable in directing those applications.
Ni-Modified Ag/SiO2 Catalysts for Selective Hydrogenation of Dimethyl Oxalate to Methyl Glycolate
Authors: Cheng Shuai , Meng Tao , Mao Dongsen , Guo Xiaoming , Yu Jun , Ma Zhen
Published: January 2022

Ni-modified Ag/SiO2 catalysts containing 0~3 wt.% Ni were obtained by impregnating Ni species onto Ag/SiO2 followed by calcination and reduction. The catalysts’ performance in the hydrogenation of dimethyl oxalate (DMO) to methyl glycolate (MG) was tested. Ag-0.5%Ni/SiO2 showed the highest catalytic activity among these catalysts and exhibited excellent catalytic stability. The effects of the Ni content on the structure and surface chemical states of catalysts were investigated by XRF, N2-sorption, XRD, TEM, EDX-mapping, FT-IR, H2-TPR, UV–vis, and XPS. The better catalytic activity and stability of Ni-modified Ag/SiO2 (versus Ag/SiO2) are ascribed to the improved dispersion of active Ag species as well as the higher resistance to the growth of Ag particles due to the presence of Ni species.
MoO3 Nanoparticle Coatings on High-Voltage 5 V LiNi0.5Mn1.5O4 Cathode Materials for Improving Lithium-Ion Battery Performance
Authors: Wu Zong-Han , Shih Jeng-Ywan , Li Ying-Jeng James , Tsai Yi-De , Hung Tai-Feng , Karuppiah Chelladurai , Jose Rajan , Yang Chun-Chen
Published: January 2022

To reduce surface contamination and increase battery life, MoO3 nanoparticles were coated with a high-voltage (5 V) LiNi0.5Mn1.5O4 cathode material by in-situ method during the high-temperature annealing process. To avoid charging by more than 5 V, we also developed a system based on anode-limited full-cell with a negative/positive electrode (N/P) ratio of 0.9. The pristine LiNi0.5Mn1.5O4 was initially prepared by high-energy ball-mill with a solid-state reaction, followed by a precipitation reaction with a molybdenum precursor for the MoO3 coating. The typical structural and electrochemical behaviors of the materials were clearly investigated and reported. The results revealed that a sample of 2 wt.% MoO3-coated LiNi0.5Mn1.5O4 electrode exhibited an optimal electrochemical activity, indicating that the MoO3 nanoparticle coating layers considerably enhanced the high-rate charge–discharge profiles and cycle life performance of LiNi0.5Mn1.5O4 with a negligible capacity decay. The 2 wt.% MoO3-coated LiNi0.5Mn1.5O4 electrode could achieve high specific discharge capacities of 131 and 124 mAh g−1 at the rates of 1 and 10 C, respectively. In particular, the 2 wt.% MoO3-coated LiNi0.5Mn1.5O4 electrode retained its specific capacity (87 mAh g−1) of 80.1% after 500 cycles at a rate of 10 C. The Li4Ti5O12/LiNi0.5Mn1.5O4 full cell based on the electrochemical-cell (EL-cell) configuration was successfully assembled and tested, exhibiting excellent cycling retention of 93.4% at a 1 C rate for 100 cycles. The results suggest that the MoO3 nano-coating layer could effectively reduce side reactions at the interface of the LiNi0.5Mn1.5O4 cathode and the electrolyte, thus improving the electrochemical performance of the battery system.
Adsorption of Carbon Dioxide with Ni-MOF-74 and MWCNT Incorporated Poly Acrylonitrile Nanofibers
Authors: Harandizadeh Amir Hossein , Aghamiri Seyedfoad , Hojjat Mohammad , Ranjbar-Mohammadi Marziyeh , Talaie Mohammad Reza
Published: January 2022

Among the new adsorbent forms, nanofiber structures have attracted extra attention because of features such as high surface area, controllable properties, and fast kinetics. The objective of this study is to produce the polyacrylonitrile (PAN) electrospun nanofibers loaded with Ni-MOF-74/MWCNT to obtain maximum CO2 adsorption. The prepared PAN/MWCNT/MOF nanofiber based on the Box–Behnken design (BBD) model suggests the CO2 adsorption of about 1.68 mmol/g (at 25 °C and 7 bar) includes 14.61 w/v%, 1.43 w/w%, and 11.9 w/w% for PAN, MWCNT, and MOF, respectively. The results showed the effective CO2 adsorption of about 1.65 ± 0.03 mmol/g (BET = 65 m2/g, pore volume = 0.08 cm3/g), which proves the logical outcomes of the chosen model. The prepared PAN/MWCNT/MOF nanofiber was characterized using different analyzes such as SEM, TEM, TG, XRD, FTIR, and N2 adsorption–desorption isotherms. More MOF mass loading on the nanofiber surface via secondary growth method resulted in 2.83 mmol/g (BET = 353 m2/g, pore volume = 0.22 cm3/g, 43% MOF mass loading) and 4.35 mmol/g (BET = 493 m2/g, pore volume = 0.27 cm3/g, 65% MOF mass loading) CO2 adsorption at 7 bar for the first and second growth cycles, respectively. This indicates that secondary growth is more effective in the MOF loading amount and, consequently, adsorption capacity compared to the MOF loading during electrospinning.
Role of Creatine Supplementation in Conditions Involving Mitochondrial Dysfunction: A Narrative Review
Authors: Marshall Robert Percy , Droste Jan-Niklas , Giessing Jürgen , Kreider Richard B.
Published: January 2022

Creatine monohydrate (CrM) is one of the most widely used nutritional supplements among active individuals and athletes to improve high-intensity exercise performance and training adaptations. However, research suggests that CrM supplementation may also serve as a therapeutic tool in the management of some chronic and traumatic diseases. Creatine supplementation has been reported to improve high-energy phosphate availability as well as have antioxidative, neuroprotective, anti-lactatic, and calcium-homoeostatic effects. These characteristics may have a direct impact on mitochondrion’s survival and health particularly during stressful conditions such as ischemia and injury. This narrative review discusses current scientific evidence for use or supplemental CrM as a therapeutic agent during conditions associated with mitochondrial dysfunction. Based on this analysis, it appears that CrM supplementation may have a role in improving cellular bioenergetics in several mitochondrial dysfunction-related diseases, ischemic conditions, and injury pathology and thereby could provide therapeutic benefit in the management of these conditions. However, larger clinical trials are needed to explore these potential therapeutic applications before definitive conclusions can be drawn.