bluuebunny/crossref_metadata_2025 huggingface dataset:
ChemInform Abstract: Stereocontrolled [m + n] Annulation Reactions. A [3 + 2] Cycloaddition of 3‐Iodo‐ 2‐[(trimethylsilyl)methyl]propene onto 1,2‐Diones.
Authors: MOLANDER G. A. , SHUBERT D. C.
Published: May 2016

Using the iodide (I) as a potential dianionic synthon and the diones (II) as the dielectrophilic partners, the diastereomers (III) are obtained as the predominant isomers on addition of SnF2.
ChemInform Abstract: Carbon Dioxide: A Reagent for the Simultaneous Protection of Nucleophilic Centres and the Activation of Alternative Locations to Electrophilic Attack.
Authors: KATRITZKY A. R. , FAN W.‐Q. , AKUTAGAWA K.
Published: May 2016

The anilines (I) are protected as lithium carbamates (III) and treated with tBuLi to give the key intermediates (IV).
ChemInform Abstract: Synthesis and Reactions of Some New 4‐(p‐Substituted Cinnamoyl)phenyl‐ 3′,4′‐xylene Sulphonates of Expected Potential Biological Activity.
Authors: HABIB O. M. O. , KHALIL A. M. , KANDEEL E. M. , ABDALLA E. B.
Published: May 2016

Die Umsetzung des Sulfonats (I) mit den aromatischen Aldehyden (II) liefert die ogß‐ungesättigten Ketone (III).
ChemInform Abstract: Synthesis and Evaluation of 2‐Substituted 1‐Methyl‐1‐(4‐tolylsulfonyl)hydrazines as Antineoplastic Agents.
Authors: HRUBIEC R. T. , SHYAM K. , COSBY L. A. , FURUBAYASHI R. , SARTORELLI A. C.
Published: May 2016

Die Umsetzung des Sulfonylhydrazins (I) mit den Säurechloriden (II) führt zu den substituierten Hydrazinen (III).
ChemInform Abstract: A Mild and Efficient SRN1 Approach to Diaryl Sulfides from Arenediazonium Tetrafluoroborates.
Authors: PETRILLO G. , NOVI M. , GARBARINO G. , DELL'ERBA C.
Published: May 2016

Diaryl sulfides such as (III) and (V) are prepared by reaction of diazonium salts (I) with thiolates (II) and (IV).
ChemInform Abstract: Synthesis of Aromatic Thioureas.
Authors: CHIRIAC C. I.
Published: May 2016

Die Herstellung der aromatischen Thioharnstoffe (IV) aus den Arylaminen (I) und Kohlenstoffdisulfid (II) wird beschrieben.
ChemInform Abstract: Metal‐Ammonia Reduction of Naphthalene at ‐33° C: Formation of Oligomeric Compounds.
Authors: DE VLIEGER J. J. , KIEBOOM A. P. G. , VAN BEKKUM H.
Published: May 2016

Naphthalin (I) wird in flüssigem Ammoniak mit Alkalimetallen oder Magnesium reduziert und anschließend mit Ammoniumchlorid protoniert.
ChemInform Abstract: Steric Effects in the Synthesis of 1,7‐Dialkylindans.
Authors: BUDHRAM R. S. , PALANISWAMY V. A. , EISENBRAUN E. J.
Published: May 2016

Aus der p‐Tolyl‐propionsäure (I) erhält man das Indanon (II), das durch Umsetzung mit entsprechenden Grignard‐Verbindungen und anschließende Hydrierung zu den Substitutionsprodukten (IV) führt.
ChemInform Abstract: Reactions of Ketene Acetals. Part 16. The Regiospecific Synthesis of Partially Methylated Purpurins.
Authors: SIMONEAU B. , BRASSARD P.
Published: May 2016

The dienes (II) and (XI) are synthesized in view of an eventu‐ 7 al application to the synthesis of the antitumor antibiotic bikaverin.
ChemInform Abstract: Regioselective Ring Cleavage of Oxiranes Catalyzed by Organotin Halide‐ Triphenylphosphine Complex.
Authors: SHIBATA I. , BABA A. , MATSUDA H.
Published: May 2016

Aus den Epoxiden (I) erhält man mit dem Benzoylchlorid (II) in Gegenwart von Dibutylzinndichlorid und Triphenylphosphin die isomeren Chlorhydrinester (III) und (IV).
ChemInform Abstract: Reactions of (2‐Oxo‐1‐azetidinyl)thiophthalimides with Nucleophiles.
Authors: IWAGAMI H. , WOULFE S. R. , MILLER M. J.
Published: May 2016

Aus den β‐Lactamen (I) werden mit Bis‐phthalimido‐sul?d (II) die Produkte (III) und (IV) gebildet.
ChemInform Abstract: The Synthesis of Thieno[3,4‐b]furan Using a Tandem Intramolecular‐Reverse Diels‐Alder Reaction Approach.
Authors: MOURSOUNIDIS J. , WEGE D.
Published: May 2016

Aus den Furan‐Derivaten (I) werden die Propargylether (II) hergestellt und über eine Grignard‐Reaktion in die Ester (III) übergeführt.
ChemInform Abstract: Pyrrole Studies. Part 36. The Synthesis of 2,2′‐Bipyrroles and Related Compounds.
Authors: HINZ W. , JONES R. A. , PATEL S. U. , KARATZA M.‐H.
Published: May 2016

Nucleophilic addition of the acyl anion of (I) ‐ generated by reaction with thiazolium salts ‐ to the butenone (II) yields the arylpentadiones (III).
ChemInform Abstract: New Antiarrhythmic Agents. 2,2,5,5‐Tetramethyl‐3‐pyrroline‐3‐carboxamides and 2,2,5,5‐Tetramethylpyrrolidine‐3‐carboxamides.
Authors: HANKOVSZKY O. H. , HIDEG K. , BODI I. , FRANK L.
Published: May 2016

Aus dem Dibrompiperidon (I) erhält man durch Reaktion mit den Aminen (II) bzw. (IV) in einer Favorski‐Umlagerung die Pyrroline (IIIa) bis (IIIg) und (V).
ChemInform Abstract: A Facile Synthesis of 4‐(Sulfonylmethyl)indoles from 4‐Oxo‐4,5,6,7‐tetrahydroindole: Formal Total Synthesis of 6,7‐Secoagroclavine.
Authors: HATANAKA N. , OZAKI O. , MATSUMOTO M.
Published: May 2016

Die 4‐Oxo‐tetrahydroindole (I) reagieren in Gegenwart von Butyllithium mit den Sulfonen (II) zu den Addukten (III), die thermisch zu den Indolylmethylsulfonen (IV) aromatisiert werden können.
ChemInform Abstract: Reaction of Copper and Silver Acetylides with Hydrazonylbromides.
Authors: UKHIN L. YU. , ORLOVA ZH. I. , BELOUSOVA L. V.
Published: May 2016

Während das Hydrazonylbromid (I) mit den Phenylacetyliden (II) in siedendem Acetonitril zu dem Hydrazon (III) reagiert, das erst ‐ bei Behandlung mit Kaliumhydroxid in Dimethylsulfoxid zu dem Pyrazol (IV) cyclisiert, bilden die Acetylide des Propargylalkohols (V) direkt das Pyrazol (VI).
ChemInform Abstract: Two Stereoisomeric Imidazoline Derivatives: Synthesis and Optical and α2‐Adrenoceptor Activities.
Authors: BIEDERMANN J. , LEON‐LOMELI A. , BORBE H. O. , PROP G.
Published: May 2016

Die Synthese der beiden Isomeren des Lofexidins (IX) erfolgt i aus dem L‐(‐)‐Weinsäureester (II).
ChemInform Abstract: Studies in Potential Filaricides. Part 18. Synthesis of 2,2′‐Disubstituted 5,5′‐Dibenzimidazolyl Ketones and Related Compounds as Potential Anthelmintics.
Authors: ABUZAR S. , SHARMA S. , FATMA N. , GUPTA S. , MURTHY P. K. , KATIYAR J. C. , CHATTERJEE R. K. , SEN A. B.
Published: May 2016

Die Tetraamine (I) cyclisieren mit den Isothioharnstoffdicarbonsäureestern (II) zu den Benzimidazolcarbonsäuren (III).
ChemInform Abstract: A Convenient Synthesis of Muscimol by a 1,3‐Dipolar Cycloaddition Reaction.
Authors: CHIARINO D. , NAPOLETANO M. , SALA A.
Published: May 2016

Dibromformaldoxim (I) liefert über das Nitriloxid (II) in einer 1,3‐dipolaren Cycloaddition mit dem Propargylamid (III) das Isoxazolderivat (IV).
ChemInform Abstract: Oxygenations of Vitamin E (α‐Tocopherol) and Its Model Compound, 2,2,5,7,8‐Pentamethylchroman‐6‐ol, in the Presence of Potassium Superoxide Suspended in Tetrahydrofuran and Unusual Acyloin Rearrangements.
Authors: MATSUMOTO S. , MATSUO M. , IITAKA Y.
Published: May 2016

Aus der als Modellverbindung für Vitamin E (a‐Tocopherol) dienenden Verbindung (I) erhält man mit Kaliumsuperoxid die beiden Oxidationsprodukte (II) und (III).
ChemInform Abstract: Synthesis and Pharmacological Evaluation of Some New Tetrahydroisoquinoline Derivatives Inhibiting Dopamine Uptake and/or Possessing a Dopaminomimetic Property.
Authors: ZARA‐KACZIAN E. , GYOERGY L. + , DEAK G. , SEREGI A. , DODA M.
Published: May 2016

Die Phenacylbromide (I) reagieren mit dem Nitrobenzylamin (II) zu den Aminoketonen (III), die nach Reduktion zu den Alkoholen (IV) mit Schwefelsäure zu den Isochinolinen (V) cyclisiert werden.
ChemInform Abstract: Novel Synthesis of Imidazo[4,5‐f]quinoline Derivatives.
Authors: PECHENINA V. M. , MUKHINA N. A. , KLIMENKO V. G. , CHISTYAKOV V. V. , GRANIK V. G.
Published: May 2016

Die Enamine des 5‐Amino‐4‐benzoylbenzimidazols (I) cyclisieren beim Erhitzen mit Polyphosphorsäure zu den Imidazochinolinen (II).
ChemInform Abstract: Synthesis of 2‐(4‐Substituted‐1‐piperazinyl)benzimidazoles as H1‐Antihistaminic Agents.
Authors: IEMURA R. , KAWASHIMA T. , FUKUDA T. , ITO K. , TSUKAMOTO G.
Published: May 2016

o‐Nitrochlorbenzol (I) wird mit dem Aminoether (II) über die aufgeführten Reaktionsstufen in das substituierte Chlorbenzimidazol (VIIe) übergeführt.
ChemInform Abstract: The Reactions of 4,5‐Dehydrotropone with Morpholine Enamines. [2 + 2]‐Cycloaddition Reaction of Dehydrotropone.
Authors: NAKAZAWA T. , ASHIZAWA M. , NISHIKAWA F. , JINGUJI M. , YAMOCHI H. , MURATA I.
Published: May 2016

Die beiden Isomere (I) und (II) reagieren mit den Enaminen (III) in Gegenwart von Blei(IV)‐acetat zu unterschiedlichen Anteilen der Verbindungen (IV)‐(VII).
ChemInform Abstract: In the Search for New Anticancer Drugs. Part 17 . Linear and Cyclic Polyether Analogues of N,N:N′,N′ :N",N"‐Tri‐1,2‐ethanediylphosphoric Triamide and N,N:N′,N′:N",N"‐Tri‐1,2‐ethanediylphosphorothioic Triamide.
Authors: SOSNOVSKY G. , LUKSZO J. , RAO N. U. M.
Published: May 2016

Der Polyetheralkohol (I) wird mit den Phosphorylchloriden (II) und anschließend mit den Aziridinen (III) zu den Phosphorsäureesteramiden (IVa)‐(IVd) umgesetzt.
ChemInform Abstract: N‐Substituted 2‐Carboxamidophenylboronic Acid Anhydrides.
Authors: ALTMANN J. , BOEHNKE H. + , STEIGEL A. , WULFF G.
Published: May 2016

Die 2‐Phenyl‐ 2‐oxazoline (I) werden zu (II) lithiiert und dann mit Trimethylborat oder Boran umgesetzt, wobei Ringöffnung zu den Boronsäuren (III) eintritt.
ChemInform Abstract: Synthesis of ω‐(Cyclopentadienyl) Alkyltriethoxysilanes.
Authors: REISSOVA A. , CAPKA M.
Published: May 2016

Die für die Fixierung von Cyclopentadien‐Liganden auf anorganischen Trägern interessanten Verbindungen (II) werden aus den Silanen (I) und Cyclopentadienyl‐natrium hergestellt.
ChemInform Abstract: Dicoordinated Phosphorus Compounds: Reaction of Disubstituted 1,4‐Diaza‐1,3‐dienes with Derivatives of Diazaphosphole and 1,2,4,3‐Triazaphosphole and Precursors of Dicoordinated Phosphorus Compounds.
Authors: DIALLO O. , BOISDON M. T. , LOPEZ L. , MALAVAUD C. , BARRANS J.
Published: May 2016

Aus den Di‐ oder Triazaphospholen (I) bzw. (V) erhält man durch Umsetzung mit den 1,4‐Diazabutadienen (II) die Addukte (III) und (VI).
ChemInform Abstract: [3 + 2]‐Cycloadditions of 1,3‐Dipoles with 1H‐1,2,4λ3‐Diazaarsolenes.
Authors: MAERKL G. + , SEITZ H.
Published: May 2016

Aus den Arsenverbindungen (I) und den Hydrazinen (II) entstehen die Diazaarsole (III).
ChemInform Abstract: Some Stable Stibonium Ylides. The Use of Bis(hexaf1uoroacetylacetonato)copper(II) as a Homogeneous Catalyst in the Conversion of Diazo‐Compounds into Ylides.
Authors: GLIDEWELL C. , LLOYD D. , METCALFE S.
Published: May 2016

The ylides (III) are prepared by reaction of (I) with (II) in the presence of the title catalyst; diazomalonic esters, however, fail to give the corresponding products.
ChemInform Abstract: Synthesis and Characterization of Phenolato and Bis‐phenolato Derivatives of Triphenylantimony(V).
Authors: IHA N. K. , MISRA A. C. , MAURYA P. L. , BAJAJ P.
Published: May 2016

Auf dem im Schema gezeigten Wege entstehen die Triphenylantimon‐Derivate (III) und (V); die Struktur und thermische Beständigkeit dieser potentiellen Flammschutzmittel werden untersucht.
ChemInform Abstract: Electrochemistry of Indium(III) Porphyrins in Pyridine and in Dichloromethane/Pyridine and Dichloromethane/N‐Methylimidazole Mixtures.
Authors: CORNILLON J.‐L. , ANDERSON J. E. , KADISH K. M.
Published: May 2016

The electrochemistry of the title complexes was studied by cyclic voltammetric measurements.
ChemInform Abstract: Nature and Composition of La(III), Ce(III), Pr(III), Nd(III), Sm(III), Gd(III), Dy(III) and Ho(III) Complexes of Embelin.
Authors: DHAR M. L. , SINGH O.
Published: May 2016

The Complexes (I) are prepared by reacting the metal ions with the biologically active ligand in ethanol (no yield given).
ChemInform Abstract: Monomeric 1,4,2,3,5λ2‐Diazadisilastannolidines and ‐Plumbolidines.
Authors: HORCHLER K. , STADER C. , WRACKMEYER B.
Published: May 2016

The title compounds (II) are prepared according to the scheme.
ChemInform Abstract: Nonplanar, 6π‐Electron Metallacyclic Alkylidene Complexes from Coupling of Coordinated Alkynes and η2‐Iminoacyls on a Tantalum Center.
Authors: CURTIS M. D. , REAL J.
Published: May 2016

Treatment of the dichloroacetylene‐Ta complexes (I) with two equiv. of MeLi gives the dimethyl analogues (II), formally 16‐electron complexes, in which the alkynes act as 4‐electron donors.
ChemInform Abstract: Bis(nitroxyl) Adducts of Bis(hexafluoroacetylacetonato)manganese(II).
Authors: DICKMAN M. H. , PORTER L. C. , DOEDENS R. J.
Published: May 2016

The reaction of the Mn complex (I) with the cyclic nitroxyl radicals (II) yields the adducts (III), which both crystallize in the space group P21/c with Z=2.
ChemInform Abstract: Electrochemistry of Nitrite Reductase Model Compounds. Part 2. Formation of an Iron Bis‐Nitro Porphyrin Complex.
Authors: FERNANDES J. B. , FENG D. , CHANG A. , KEYSER A. , RYAN M. D.
Published: May 2016

The reaction of the complexes (I) with nitrite is studied by UV/visible, 1H NMR, and IR spectroscopy and by electrochemistry and shows the appearance of mono‐ and bis‐nitrite complexes.
ChemInform Abstract: Gas‐Phase Nucleophilic Addition Reactions of Negative Ions with Transition‐Metal Carbonyls.
Authors: LANE K. R. , SALLANS L. , SQUIRES R. R.
Published: May 2016

Gas‐phase ion‐molecule reactions between Fe(CO)5 and an extensive series of negative ions X′(NH2′ , H′, OH′, HS′, N3′ , F′, C1′, Br′, I′, and 22 organic anions) are investigated with a flowing afterglow apparatus operating at 300 K. Reaction generally proceeds by nucleophilic addition to generate the species (CO)4FeC(O)X′, (CO)4FeX′, and (CO)3FeX′.
ChemInform Abstract: Counterion Effects on the Intramolecular Electron‐Transfer Rate of Mixed‐Valence Biferrocenium Salts: Micromodulation and Phase Transitions.
Authors: DONG T.‐Y. , KAMBARA T. , HENDRICKSON D. N.
Published: May 2016

The effect of changing the counterion from I3′ to I2Br′, Brzl′ or PF; on the rate of intramolecular electron transfer in the mixed valence biferrocenium cation (I) is examined.
ChemInform Abstract: Alkaline Hydrolysis of t‐[Co(tren)(NH3)SCN]2+ and Other t‐ and p‐ [Co(tren)(NH3)X]2+ Complexes.
Authors: GAUDIN M. J. , CLARK C. R. , BUCKINGHAM D. A.
Published: May 2016

Alkaline hydrolysis of the p‐complex (IIb) results in only (IIc), but hydrolysis of the t‐complex (Ib) gives the t‐complex (IIIa) (35%), the t‐complex (Ia) (5%), as well as the p‐complex (IIc) (50%) and the t‐complex (Ic) (10%).
ChemInform Abstract: Reductive Addition of OH Radicals to Macrocyclic Complexes.
Authors: GEIGER D. K. , FERRAUDI G.
Published: May 2016

The reactions of OH radicals with the complexes (I) and (II) have been investigated by pulse radiolysis.
ChemInform Abstract: Synthesis and Reactivity of [η5‐C5R5)Ru(η6‐arene)]PF6 (R: H, CH3) Complexes of Naphthalene, Anthracene, Pyrene, Chrysene, and Azulene. Kinetic Studies of Arene Displacement Reactions in Acetonitrile Solutions.
Authors: MCNAIR A. M. , MANN K. R.
Published: May 2016

The preparation of the title Compounds (II) and (III) by replacement of the MeCN ligands in (I) is particularly facile, requiring very little or no heat and short reaction times.
ChemInform Abstract: Polyaza Cavity‐Shaped Molecules. Part 9. Ruthenium(II) Complexes of Annelated Derivatives of 2,2′ :6,2"‐Terpyridine and Related Systems: Synthesis, Properties, and Structure.
Authors: THUMMEL R. P. , JAHNG Y.
Published: May 2016

The title complexes (IV) are prepared by reaction of the ligands (I)‐(III) with RuCl3 ‐ 3 H2O in EtOH/HZO (1 :l).
ChemInform Abstract: Spectral Evidence for the Formation of Active Intermediates from RuCl3 and RuC12(PPh3)3 with N‐Methylmorpholine N‐Oxide (NMO) and Phenyliodosoacetate (PIA) as Mild Oxidants.
Authors: VIJAYASRI K. , RAJARAM J. , KURIACOSE J. C.
Published: May 2016

IR, electronic, and EPR spectroscopic investigations show evidence for the formation of the three active intermediates ‐ Ru(VIII), Ru(V)‐oxo species, and Ru(II)‐triphenylphosphine oxide complex ‐ in the case of the RuC13/PIA system in acetic acid, RuC13/NMO system in DMF, and RuC12(PPh3)3/NMO system, respectively.
ChemInform Abstract: Complexes of Hybrid Ligands. Synthesis of Mixed‐Ligand, Phosphino‐Alkoxide Complexes of Pd2+: the Crystal and Molecular Structure of the Complex Ph2PCH2C(CF3)2OPdCl(PPh2Me).
Authors: MONTGOMERY C. D. , PAYNE N. C. , WILLIS C. J.
Published: May 2016

The Pd Complex (I), prepared from a hybrid phosphino‐alkoxide ‐ligand, reacted with (II) to give the dinuclear compound (III).
ChemInform Abstract: Microbiological Transformations. Part 6. Biohydroxylations in the Pinane Series.
Authors: ARCHELAS A. , FOURNERON J. D. , VIGNE B. , FURSTOSS R.
Published: May 2016

Racemates of the amides (I), when incubated with B. sulfurescens, are hydroxylated regioselectively to give the alcohols (II).
ChemInform Abstract: Unusual Acetone Solvation of a Longibornane‐Based C‐3 Carbonyl in Neighbouring Group Participation: Unique Reactivity of 12‐Bromolongibornane‐3,4‐dione.
Authors: VAIDYA S. P. , NAYAK U. R.
Published: May 2016

An attempt to oxidize the dione (Ia) with H2O2 in an alkaline acetone solution leads to the formation of the product (IIIa) which is also obtained in the absence of H2O2.
ChemInform Abstract: Bimanes. Part 18. (Haloalkyl)‐1,5‐diazabicyclo[3.3.0]octadienediones (Halo‐9,10‐dioxabimanes): Sulfur "Extraction" by syn‐(1‐Bromoethy,methyl)bimane. Glutathione "Sulfide" from the Tripeptide Thiol, Glutathione.
Authors: RADKOWSKY A. E. , KOSOWER E. M. , EISENBERG D. , GOLDBERG I.
Published: May 2016

Glutathione (II) and the diastereomeric (meso, dl) dibromides (Ib) [= syn‐(1‐bromoethyl,methyl)bimanes] derived from (Ia) react to yield the cis and trans isomers of the thia‐bridged bimane (III), the bimane (IV), the disulfide (Va), and the title compound (Vb) (1:1 mixture of diastereomers).
ChemInform Abstract: N‐(Glucopyranosid‐3‐yl)‐D‐alanyl‐L‐alanyl‐D‐isoglutamine and Related Tripeptide Analogues of Muramyl Dipeptide.
Authors: CALVO‐MATEO A. , CAMARASA M.‐J. , DE LAS HERAS F. G.
Published: May 2016

The four analogues (VIIa)‐(VIId) of the immunoadjuvant Muramyl dipeptide in which the D‐lactic acid moiety is replaced by D‐ and L‐alanine are prepared: The isomeric condensation products (III) and (IV) are obtained from the glucopyranosides (I) and the D,L‐ester (II); hydrolysis of (IIIb), (IVb) to (IIIc), (IVc), and subsequent condensation with the dipeptide ester (Va) (as the trifluoroacetate) or (Vb) (as the hydrochloride) affords the D‐alanyl derivatives (VIa), (VIb) or the L‐isomers (VIc), (VId), resp., from which the target compounds (VII) are obtained by hydrogenolysis.
ChemInform Abstract: Derivatives of 3‐Hetero‐1,5‐dialdehydes. Part 15. Synthesis of C‐Glycopyranosylfuran Derivatives by Reaction of Dialdehydes with Cyanoacetamide.
Authors: LOPEZ APARICIO F. J. , SANTOYO GONZALEZ F. , GARCIA MENDOZA P. , DOMINGUEZ MARTINEZ J. A.
Published: May 2016

Durch Umsetzung der Dialdehyde(I) mit Cyanacetamid entstehen die heterocyclischen Verbindungen (II) als Hauptprodukte; als Nebenprodukte werden die Dihydropyrane(III) isoliert.
ChemInform Abstract: Total Synthesis of (+)‐Dihydromevinolin.
Authors: HECKER S. J. , HEATHCOCK C. H.
Published: May 2016

The synthesis of the title compound (XII) is carried out as shown in the scheme starting from the tricyclic ketone (I).
ChemInform Abstract: Synthesis of the Proposed Penultimate Biosynthetic Triene Intermediate Monensin A.
Authors: PATEL D. V. , VANMIDDLESWORTH F. , DONAUBAUER J. , GANNETT P. , SIH C. J.
Published: May 2016

The chiral synthons (III), (VIII) and (XIII) are coupled successively to give the sodium salt of the title triene.
ChemInform Abstract: Chiral Synthesis of Polyketide‐Derived Natural Products. Part 10. Stereoselective Synthesis of Pikronolide, the Aglycon of the 14‐Membered Ring Macrolide Pikromycin, from D‐Glucose. Role of MPM and DMPM Protection.
Authors: NAKAJIMA N. , HAMADA T. , TANAKA T. , OIKAWA Y. , YONEMITSU O.
Published: May 2016

The synthesis of picronolide (IXb) Starts with the addition of crotyltributylstannane to the aldehyde obtained by Swern oxidation of the alcohol (I) to give (II) in an erythro‐selective reaction.
ChemInform Abstract: Enantioselective Total Synthesis of (+)‐Negamycin and (‐ )‐Epinegamycin by an Asymmetrie 1,3‐Dipolar Cycloaddition.
Authors: IIDA H. , KASAHARA K. , KIBAYASHI C.
Published: May 2016

(+)‐Negamycin (X), the natural product, has been synthesized with D‐gulono‐y‐lactone (I) as starting compound via the trans‐alcohol (VIa).
ChemInform Abstract: Stereocontrolled Functionalization of Cycloheptadiene. An Approach to Tylosin and Carbomycin B from a Common Intermediate.
Authors: PEARSON A. J. , RAY T.
Published: May 2016

Aus dem Eisencarbonyl‐Komplex (I) läßt sich das Cycloheptadien‐Derivat (II) herstellen, das durch Einwirkung von . N‐Bromsuccinimid und anschließende Alkylierung über das Lacton (III) zu (IV) führt.
ChemInform Abstract: Immobilized Penicillinacylase: Application to the Synthesis of the Dipeptide Aspartame.
Authors: FUGANTI C. , GRASSELLI P. , CASATI P.
Published: May 2016

Durch an Eupergit Cimmobilisierte Penicillinacylase (EC 3.5.1.11) kann N‐ Phenacetylaspartame (I) selektiv in den Süßstoff Aspartame (II) gespalten werden; daneben entsteht Phenylessigsäure.
ChemInform Abstract: Dynamics of Dissociation and Energy Transfer in Molecular Collisions with Solid Surfaces.
Authors: GERBER R. B. , AMIRAV A.
Published: May 2016

Review: (description of results obtained in collaboration between the respective theoretical and experimental groups of authors over the past few years; including molecules such as I2 in collision with single‐crystal surfaces of MgO, diamond, and sapphire ‐ ca. 40 refs.
ChemInform Abstract: Fluorides and Fluoro Acids. Part 10. Crystal Structures of Acid Hydrates and Oxonium Salts.
Authors: MOOTZ D. , WIEBCKE M.
Published: May 2016

The low‐temp. form of H3OAsF6, which is stable up to 275 K, crystallizes in the triclinic system, space group PT with Z=2.
ChemInform Abstract: Photoassisted and Electrochemical Reduction of Nitric Acid to Hydroxylamine and Ammonia.
Authors: HALMANN M. , TOBIN J. , ZUCKERMAN K.
Published: May 2016

The reduction of N03′ to give NHzOH and NH3 in aqueous media containing 2 M H3PO4 has been achievgd electrochemically at a Pt cathode, photoe‐lectrochemically at an illuminated p‐GaP electrode, or by photoassisted reaction using illuminated suspensions of "[102 or SrTiO3 powders.
ChemInform Abstract: Highly Diastereoselective Titanium Tetrachloride‐Mediated Aldol Condensation of the Bistrimethylsilyl Enol Ether of Acetoacetic Ester with 2‐Benzyloxyhexanal.
Authors: HAGIWARA H. , KIMURA K. , UDA H.
Published: May 2016

Aldol condensation of the two acetoacetic ester synthons (II) or (IV) with 2‐benzyloxyhexanal (I) is investigated under various conditions.
ChemInform Abstract: Trimethylsilyl Cyanide ‐ A Reagent for Umpolung. Part 12. Intramolecular Diels‐ Alder Reaction of Dienals via Umpolung.
Authors: FISCHER K. , HUENIG S. +
Published: May 2016

Umpolung of the dienals (I) with respective silyl cyanides (II) and reaction of the products (III) with the olefinic alkylating reagents (IV) furnishes the products (V).
ChemInform Abstract: Lewis Acid Catalyzed Rearrangements of Structurally Related αβ‐Unsaturated Epoxy Ketones and Oximes.
Authors: BACH R. D. , TUBERGEN M. W. , KLIX R. C.
Published: May 2016

By treatment with BF3 the epoxy octalinone (I) rearranges to form a mixture of (II) and (III).
ChemInform Abstract: Vapour‐phase Chemistry of Arenes. Part 12. Reaction of Chlorobenzene and Derivatives with Hydroxyl Radicals at Approx. 290 °C. Hydroxy‐dechlorination.
Authors: MULDER P. , LOUW R.
Published: May 2016

The action of hydroxyl radicals generated from tert. butyl hydroperoxide at 290°C on the title compounds (I) results in a hydroxy‐dechlorination to give the compounds (II) besides the formation of the arene‐derived products (II)‐(VI) and the compounds (VII) and (VIII), formed by displacement of CF; rather than Cl.
ChemInform Abstract: Si‐C Bond Cleavage in Silyl Alkynes Under Phase Transfer Catalysis. Applications to the Synthesis of Epoxyhexenynes.
Authors: ROSER J. , EBERBACH W.
Published: May 2016

The trimethylsilyl alkyne (I) is hydrolyzed to give the alkyne (II) under phase transfer conditions.
ChemInform Abstract: Pyridazine Compounds. Part 20. 6H‐1,2,4‐Triazino[4,3‐b]1,2,4‐triazolo[3,4‐f]pyridazine, a Novel Angular Ring System.
Authors: KOSARY J. , JERKOVICH G. , POLOS K. , KASZTREINER E.
Published: May 2016

Treatment of the hydrazones (II) and (III) with PPA in the heat does not lead to the expected 7‐methyl derivatives of the title ring system but, by a reaction owing to a pyruvate exchange with the Starting material, to the methacrylates (IV) and (V).
ChemInform Abstract: Derivatives of o‐Phenylene Esters of Phosphoric Acid. Part 33. Chlorination of Bis(o‐methoxyphenyl)chlorophosphite ‐ a Double Cyclization with Ether Cleavage.
Authors: GLOEDE J.
Published: May 2016

The title reaction of (I) gives the P(V) spiro compound (II) which is also obtained by a 2:1 molar reaction of guaiacol with PCl5.
ChemInform Abstract: Stereocontrolled Acylation of (η4‐Cycloheptatriene) Iron Tricarbonyl.
Authors: WILLIAMS G. M. , RUDISILL D. E.
Published: May 2016

Cycloheptatrienyl iron tricarbonyl (I) is acylated with the chlorides (I I) to produce the derivatives (III); only small quantities of the isomers (IV) are obtained.
ChemInform Abstract: Conformational Characterization of the Stereoisomers of a Nickel(II) Macrocyclic Tetraamine Complex.
Authors: CHEN J.‐W. , CHUNG C.‐S.
Published: May 2016

The complex ion (I) can exist in 20 theoretically possible diastereoisomeric forms, depending on the configurations of the two asym. carbon and the four asym. nitrogen Centers.
ChemInform Abstract: Angiotensin Converting Enzyme Inhibitors as Antihypertensive Agents: 1‐[(2‐Mercaptocycloalkyl)carbonyl]‐L‐prolines.
Authors: CIABATTI R. , PADOVA G. , BELLASIO E. , TARZIA G. , DEPAOLI A. , BATTAGLIA F. , CELLENTANI M. , BARONE D. , BALDOLI E.
Published: May 2016

Aus den Cycloalkencarbonsäuren (I) werden,wie im Formelschema skizziert, die Prolin‐Derivate (VI) und (IX)‐(XIV) dargestellt.
ChemInform Abstract: Nucleosides. Part 137. (Trifluoromethyl)sulfonyl (Triflyl) Migration. Synthesis of 6,3′‐Anhydro‐3‐benzyl‐1‐(5‐chloro‐5‐deoxy‐β‐D‐xylofuranosyl)barbituric Acid from the 2′‐Trifluoromethanesulfonate (Triflate) of 6,5′‐Anhydro‐3‐benzyl‐1‐β‐D‐ribo‐furanosylbarbituric Acid.
Authors: PANKIEWICZ K. W. , NAWROT B. C. , WATANABE K. A.
Published: May 2016

Aus dem Barbitursäurederivat (I) erhält man mit Trifluormethansulfochlorid die Folgeprodukte (IIa) und (IIIa), die zu (IIb) und (IIIb)acetyliert werden.
ChemInform Abstract: A γ‐Lactam Analogue of Penems Possessing Antibacterial Activity.
Authors: BALDWIN J. E. , LOWE C. , SCHOFIELD C. J. , LEE E.
Published: May 2016

The aspartic semi‐aldehyde ester (I) is combined with the cysteine ester hydrochloride (II) to yield the diastereomeric thiazolidines (III).
ChemInform Abstract: Analogues of Platelet Activating Factor. Part 4. Some Modifications of the Phosphocholine Moiety.
Authors: WISSNER A. , SCHAUB R. E. , SUM P.‐E. , KOHLER C. A. , GOLDSTEIN B. M.
Published: May 2016

Durch Kondensation der Glycerinether (I) mit den Phosphor‐Reagentien (II) werden die Verbindungen (III) erhalten und in die Acetate (IV) übergeführt. Ferner wird aus (Ib) durch Umsetzung mit Dibrombutan über die Stufen (V) und (VI) das Derivat (VII) synthetisiert, in dem die Phosphocholin‐Gruppe durch einen substituierten Ammoniumrest ersetzt ist.
ChemInform Abstract: Methylchrysenes as Probes for the Mechanism of Metabolic Activation of Carcinogenic Methylated Polynuclear Aromatic Hydrocarbons.
Authors: HECHT S. S. , MELIKIAN A. A. , AMIN S.
Published: May 2016

Review: (review of the basic relationships between structure and tumorigenicity.
ChemInform Abstract: Can F2H+ Exist in the Topological Form FHF+ ?
Authors: DEKOCK R. L. , DUTLER R. , RAUK A. , VAN ZEE R. D.
Published: May 2016

Ab initio calculations on both topologies F FH+ and FHF+ show that F2H+ cannot have an independent existence because the only energy minimum is that provided by the C5 structure corresponding to protonated F2.
ChemInform Abstract: Crystal Structure of La3Ni4Ge4.
Authors: BRUSKOV V. A. , BODAK O. I. , PECHARSKII V. K.
Published: May 2016

A compound of unknown structure, whose composition has been found to be La3Ni4Ge4 has been discovered studying phase diagrams of the system La‐Ni‐Ge.
ChemInform Abstract: Reduction of Cr(III) in Concentrated Aqueous Electrolytes at a Dropping Mercury Electrode.
Authors: ANDREU R. , SANCHEZ F. , GONZALEZ‐ARJONA D. , RUEDA M.
Published: May 2016

Astudy of Cr(III) reduction in highly concentrated NaCl, NaI and Na2SO4 solutions demonstrates the important role of the solvation environment in outer‐sphere electrochemical reactions.
ChemInform Abstract: Catalytic Water Decomposition via Novel Bimetallic Systems.
Authors: JEONG K. M. , SWIFT H. E.
Published: May 2016

The Zn‐ H2O reaction has been investigated under mild conditions (303, 333, and 353 K) using Zn powder with electrochemically dispersed metals (Ag, Ni, Fe, Au, Pd, Ru, Rh) on its surface.
ChemInform Abstract: Catalytic Properties of Tricomponent Metal Oxides Having the Scheelite Structure.
Authors: UEDA W. , ASAKAWA K. , CHEN C.‐L. , MORO‐OKA Y. , IKAWA T.
Published: May 2016

It is shown that the substitution of V5+ by Mo6+ in Bi1‐x/3V1‐xMoxO4 (0 ⩽ x ⩽ 1) catalysts increases the catalytic activity in C3H6 oxidation without changing the selectivity.
ChemInform Abstract: High Catalytic Activity of NiO ‐ TiO2 / SO42‐ for Ethylene Dimerization.
Authors: SOHN J. R. , KIM H. J.
Published: May 2016

The catalytic activity in ethylene dimerization has been determined for a series of NiO‐ TiO2 / SO4)2‐ ; Catalysts prepared by coprecipitation from a NiCl2 / TiCl4 solution followed by a H2SO4 treatment.
ChemInform Abstract: Selective Reduction of Nitric Oxide on Nickel Oxide ‐ Copper Oxide Supported Catalysts.
Authors: BLANCO J. , GARCIA DE LA BANDA J. F. , AVILA P. , MELO F.
Published: May 2016

The NO reduction with NH3 (in the presence and absence of O2) over NiO‐ CuO/ Al2O3 has been studied at atmospheric pressure in the temp. range 200‐300°C in order to develop an industrial process for reducing the NOX emissions from nitric acid plants.
ChemInform Abstract: Ammonia Synthesis on Molybdenum Nitride.
Authors: VOLPE L. , BOUDART M.
Published: May 2016

It is shown that the NH3 synthesis over Mo2N is sensitive to the surface structure of the catalyst and that the amount of active sites decreases with decreasing particle size.
ChemInform Abstract: Synthesis and Electric Properties of a Binary Oxide of Lanthanum and Nickel.
Authors: SAVCHENKO V. F. , LYUBKINA I. YA.
Published: May 2016

A mixture of lanthanum oxalate and nickel oxalate is heated to 670 K for 1 h and then to 1370 K for 56 h. A binary oxide of La and Ni is isolated, which contains La and Ni in an 1.50 gram atom ratio.
ChemInform Abstract: Group 4 Organometallic Reagents. Part 2. Enantiomeric Purity Determination of 1,2‐Diols Through NMR Spectroscopy without Chiral Auxiliaries.
Authors: LUCHINAT C. , ROELENS S.
Published: May 2016

The e.e. of various mixtures of enantiomers of the Sn derivatives (Ib), obtained by treating chiral diols (Ia) with Bu2SnO, are determined (accuracy ± 2%) by means of 13C NMR spectroscopy.
ChemInform Abstract: Theoretical Determination of Molecular Structure and Conformation.
Authors: CREMER D. , KRAKA E. , GAUSS J. , BOCK C. W.
Published: May 2016

In contrast to (I) bridge inversion occurs in (II) with a larger annulene perimeter and proceeds predominantly via an inversion at the ether O‐atom on heating.
ChemInform Abstract: X‐Ray Analyses and Structure‐Activity Relations of Antiprogestins.
Authors: HERRMANN C. , HOYER G.‐A. , NEEF G. , SCHOMBURG D. , WIECHERT R.
Published: May 2016

The crystal structures of the steroids (I) and (II) (both space group P2,2,2,; Z=4) are determined.
ChemInform Abstract: Novel Organometallic Ionophore with Specificity Toward Li+.
Authors: SHINAR H. , NAVON G. , KLAUI W.
Published: May 2016

The ionophoric properties of the organometallic ligand (I) is studied by following its effect on the rate of transport of Na+ and Li+ across artificial phospholipid vesicles using "Na and 7Li NMR.
ChemInform Abstract: Charge‐Transfer Interaction Between N,N‐Dimethylaniline and Aromatic Sulphonyl Chlorides.
Authors: KOTHANDARAMAN H. , ARUMUGASAMY N.
Published: May 2016

The donor‐ acceptor interactions of N,N‐dimethylaniline with toluene‐p‐sulphonyl Chloride, toluene‐o‐sulphonyl Chloride, and benzenesulphonyl Chloride are investigated by UV‐visible spectroscopy.
ChemInform Abstract: Oxazoles as Dienophiles in Diels‐Alder Reactions.
Authors: DONDONI A. , FOGAGNOLO M. , MASTELLARI A. , PEDRINI P. , UGOZZOLI F.
Published: May 2016

The oxazoles (Ia) and (Ib) react with tetrachloro‐o‐quinone (II) producing the adducts (III); analogous adducts (Va) and (Vb) are obtained from (Ia) and the cyclopentadiene derivatives (IVa) and (IVb).
ChemInform Abstract: Polymerization and Cross‐Linking of Alkenyl‐1,2,3‐thiadiazoles.
Authors: PIEPER M. , MEIER H.
Published: May 2016

The vinylthiadiazoles (I) can be polymerized in radical (using dibenzoyl peroxide) or cationic (using BF3 · Et2O ) processes.
ChemInform Abstract: β‐Hydride Elimination from Methoxo vs. Ethyl Ligands: Thermolysis of (DPPE)Pt(OCH3)2, (DPPE)Pt(CH2CH3)(OCH3) and (DPPE)Pt(CH2CH3)2.
Authors: BRYNDZA H. E. , CALABRESE J. C. , MARSI M. , ROE D. C. , TAM W. , BERCAW J. E.
Published: May 2016

Kinetics experiments, labeling studies, and solvent effects suggest the thermolysis of the dimethoxo complex (at 25°C) proceeds by initial preequilibrium β‐hydride migration to the metal followed by rate‐limiting release of organic products [MeOH, (CHO)x and small amounts of CO].
ChemInform Abstract: Remote Intramolecular Functionalization of Arylnitrenium Ions: Synthesis of Aminodihydrophenanthridines and Benzo[c]chromans.
Authors: ABRAMOVITCH R. A. , COOPER M. M. , JEYARAMAN R. , RUSEK G.
Published: May 2016

The azido derivative (I) is converted to the amines (II).
ChemInform Abstract: Photosensitized Electron‐Transfer Reactions in β‐Cyclodextrin Aqueous Media: Effects on Dissociation of Ground‐State Complexes, Charge Separation, and H2 Evolution.
Authors: ADAR E. , DEGANI Y. , GOREN Z. , WILLNER I.
Published: May 2016

In the presence of β‐cyclodextrin, the photosensitized reduction of anthraquinone‐2‐sulfonate (I), using the neutral Zn porphyrin complex (II), and cysteine as the electron donor is possible.
ChemInform Abstract: ipso Substitution by Cyanide Anion in Photolysis of 1‐(p‐Methoxyphenyl)vinyl Bromides.
Authors: KITAMURA T. , MURAKAMI M. , KOBAYASHI S. , TANIGUCHI H.
Published: May 2016

The vinyl bromides (I) react with cyanides under photolytic conditions to give mixtures of the nitriles (II)‐(V).
ChemInform Abstract: Different Reactivity of N‐ and S‐Methylides Towards Electrophilic Reagents.
Authors: WITTMANN H. , ZIEGLER E.
Published: May 2016

Without using inorganic and organic acids the methylide (II) is formed from the ylide (I) in a one‐step reaction in the presence of aniline, the latter mode being more suitable than the former ones.
ChemInform Abstract: Generation and Characterization of 2,6‐Azulylene.
Authors: KOENIG T. , RUDOLF K. , CHADWICK R. , GEISELMANN H. , PATAPOFF T. , KLOPFENSTEIN C. E.
Published: May 2016

Hofmann elimination from the ammonium hydroxide (IV) [obtained from (I) via (III), with the hydrolysis of the mixture of esters (II) as a highly selective step] affords the cyclophanes (V).
ChemInform Abstract: Radical Reactions of Carbohydrates. Part 6. An ESR Study of the Reaction of the Hydroxyl Radical with Some Lactones Derived from Sugars and with Ascorbic Acid.
Authors: FITCHETT M. , GILBERT B. C.
Published: May 2016

The D‐ribono‐γ‐lactone (I) is oxidized to give the radicals (II)‐(IV) whereby the H‐abstraction occurs preferentially from the position adjacent to the carbonyl group.
ChemInform Abstract: Substituent and Temperature Effects on the Reactions of Benzylchlorocarbene with Alcohol.
Authors: LIU M. T. H. , SUBRAMANIAN R.
Published: May 2016

Based on the product ratios (V)/ (IV), the isomer ratlos (E‐V)/(Z‐V), and the second‐order dependence in alcohols it is concluded that electron‐releasing groups favor rearrangement while electron‐withdrawing groups facilitate insertion to give the acetals (IV) via an ylide intermediate (III) formed reversibly by carbene (II) attack on an alcohol dimer.
ChemInform Abstract: Oxidation by Cobalt(III) Acetate. Part 10. Effects of Ring Substituents on the Product Distributions in the Oxidation of β‐Methylstyrenes by Cobalt(III) Acetate in Acetic Acid.
Authors: MORIMOTO T. , HIRANO M. , ECHIGOYA K. , SATO T.
Published: May 2016

Product analysis and kinetic studies show that electron‐releasing groups accelerate both the reaction rate and the formation of (II) while electronwithdrawing groups not only retard the reaction but also favor the formation of (III).
ChemInform Abstract: Use of Alumina for Elimination of Sulfinic Acid from β‐Acyl‐ and β‐Alkylsulfonyl Carbonyl Compounds.
Authors: VIDAL J. , HUET F.
Published: May 2016

Sulfinic acid is eliminated from the sulfone (I) in the presence of DBU.
ChemInform Abstract: SmI2‐Induced Iodomethylation of Carbonyl Compounds.
Authors: TABUCHI T. , INANAGA J. , YAMAGUCHI M.
Published: May 2016

The ketones (I) react with dihalomethanes (II) in the presence of Smlz to produce the iodohydrines (III).
ChemInform Abstract: The Reaction of N‐Alkylhydroxamic Acids with Sulphinyl Chlorides.
Authors: BANKS M. R. , HUDSON R. F.
Published: May 2016

The reaction of the hydroxamic acids (I) with the corresponding sulphinyl chlorides leads below 0 °C to the O‐sulphinated intermediate (II) which isomerizes to give the products (III)‐(V) via in‐cage and free pair radical combination.
ChemInform Abstract: Kinetics of Deuterium Isotope Exchange Between 2‐Methylpropane‐2‐thiol and Propane‐2‐thiol in Aprotic Solvents.
Authors: WAWER A.
Published: May 2016

Decrease in the rate constants of the bimolecular H/ Dexchange and the activation enthalpy and enhancement of the activation entropy with increasing ability of the solvents to form hydrogen bonds (e.g.
ChemInform Abstract: Kinetics and Mechanisms of Nucleophilic Displacement with Heterocycles as Leaving Groups. Part 21. Identification of the Products of Solvolysis of N‐Benzylpyridinium Cations in the Absence of Nucleophiles.
Authors: KATRITZKY A. R. , MARSON C. M. , CHEN J.‐L. , SACZEWSKI F. , KING R. W.
Published: May 2016

The salts (I), (VIIa), and (VIIc) undergo thermolysis in chlorobenzene as solvent to give products of benzylation both of the solvent and the pyridine leaving group (cf. scheme).
ChemInform Abstract: Irreducible Analogues of Mevaldic Acid Coenzyme A Hemithioacetal as Potential Inhibitors of HMG‐CoA Reductase. Part 2. Synthesis of a Secondary Alcohol Analogue of Mevaldic Acid Pantetheine Hemithioacetal and an Amide Analogue of 3‐Hydroxy‐3‐methylglutaryl‐S‐pantetheine.
Authors: TURAKHIA R. H. , FISCHER G. C. , MORROW C. J. , MASCHHOFF B. L. , TOUBBEH M. I. , ZBUR‐WILSON J. L.
Published: May 2016

Als nicht‐weiterreduzierbare Analoga zur Teilstruktur (Ia) des Mevaldinsäure‐Coenzym A‐Hemiacetals werden die Verbindungen (Ib) und (Ic) hergestellt, die nur schwache Wirkung als HMG‐CoA‐Reduktase‐ ‐Inhibitoren zeigen.
ChemInform Abstract: A Novel Approach to cis‐Chrysanthemic Acids.
Authors: MANN J. , THOMAS A.
Published: May 2016

Addition of 2‐diazopropane (II) to the butenolide (I) and subsequent photochemical elimination of nitrogen yield the bicyclic lactone (V), which can be converted stereospecifically to the isomeric chrysanthemum acids (IX) or (XIII).
ChemInform Abstract: Reaction of Acetoxyfulvene with Dichloro Ketene.
Authors: TOLSTIKOV G. A. , MIFTAKHOV M. S. , AKHMETVALEEV R. R. , KHALIKOV L. M.
Published: May 2016

Dichloroketene, which is generated by C12CHCOCl/NEt3, adds to‐the fulvene (I) to yield the adduct (II).
ChemInform Abstract: A New Preparation of α‐Cycloheptatrienyl Ketones.
Authors: REINGOLD I. D. , TRUJILLO H. A. , KAHR B. E.
Published: May 2016

Tropylium‐tetrafluoroborat (I) reagiert mit den Ketonen (II) zu den Cycloheptatrienylketonen (III).
ChemInform Abstract: Reaction of Tricyclo[3.2.0.02,7]hept‐3‐ene with Diazomethane in the Presence of Palladium Diacetate.
Authors: KAZIMIRCHIK I. V. , LUKIN K. A. , ZEFIROV N. S.
Published: May 2016

The title compound (I), an unstable isomet of norbornadiene, affords on treatment with CH2N2 in the presence of Pd(OAc)2 the tetracyclooctane (II).
ChemInform Abstract: Facile Stereoselective Reductions of Enediones and Cage Diketones Using NaBH4‐CeC13.
Authors: MARCHAND A. P. , LAROE W. D. , SHARMA G. V. M. , SURI S. C. , REDDY D. S.
Published: May 2016

Das Kä?g‐dion (I) wird mit NaBH4 und CCCI3 stereoselektiv zu dem Diol (II) reduziert und dieses sauer zu dem cyclischen Ether (III) dehydratisiert.
ChemInform Abstract: N‐Arylacyl and N‐Arylalkyl Derivatives of 2‐Amino‐1‐butanol with Two Chiral Centers.
Authors: ECKSTEIN M. , CEGLA M. , GAJEWCZYK L.
Published: May 2016

Die Umsetzung von optisch reinen Säurechloriden (I) mit den als Tartraten eingesetzten Aminobutanolen (II) in ebenfalls enantiomerenreiner Form liefert alle möglichen Stereoisomeren (IIIa)‐(IIId).
ChemInform Abstract: Novel Reactivity of 2‐(Chloromethoxy)ethyl Acetate.
Authors: AITKEN D. J. , REES L. , SUCKLING C. J. , WOOD H. C. S.
Published: May 2016

2‐(Chloromethoxy)ethyl acetate (I) reacts with alcohols in the presence of silver carbonate to give mixtures of the compounds (III) and (IV).
ChemInform Abstract: The Synthesis of α‐Branched Cinnamyl Aldehydes and of Their Oximes.
Authors: UNTERHALT B. , ELJABOUR S.
Published: May 2016

Durch spezifische Reaktionsbedingungen lassen sich aus dem p‐Fluorzimtaldehyd (I I) gezielt die E‐ bzw. Z‐Oxime (I) bzw. (III) herstellen.
ChemInform Abstract: A New Transformation Method of N‐Alkylphtnhalimides to N‐Alkylformamides with N,N‐Dimethylformamide and Hydrazine Hydrate.
Authors: IWATA M. , KUZUHARA H.
Published: May 2016

The phthalimides (I) are cleaved with hydrazine in DMF to produce the formamides (II), dimethylamine (III) and phthalhydrazide (IV).
ChemInform Abstract: Ring Opening of 3‐Methoxyacenaphthylene‐1,2‐dione. Application of 13C‐ 2D‐Inadequate‐NMR Spectroscopy to Structure Assignment of Some Substituted Naphthalenes.
Authors: BECKER D. , GOTTLIEB L. , LOEWENTHAL H. J. E.
Published: May 2016

The cleavage of the acenaphthylene diones (I) gives the oxo acids (II) or (III).
ChemInform Abstract: Diastereomeric Atropisomers of the Tricyclo[9.3.1.03,8]pentadecane Ring System.
Authors: SHEA K. J. , GILMAN J. W. , HAFFNER C. D. , DOUGHERTY T. K.
Published: May 2016

The Diels‐Alder precursor (VI) is obtained in 30% overall yield from the methoxy ester (I) via (III) and (V).
ChemInform Abstract: Quinone‐Amine Reactions. Part 20. 1,4‐Naphthoquinone Derivatives of Psychopharmacological Agents with Secondary Amine Structure.
Authors: KALLMAYER H.‐J. , TAPPE C.
Published: May 2016

Analog zu p‐Benzochinon reagiert Naphthochinon (I) mit den sekundären Aminen (II) zu den orangeroten Aminonaphthochinonen (III).
ChemInform Abstract: Studies of the Ketone Obtained from the Ozonolysis of Vitamin D. Molecular Mechanics Calculations for It and Related Hydrindanones.
Authors: PETERSON P. E. , BREEDLOVE LEFFEW R. L. , JENSEN B. L.
Published: May 2016

Der durch Ozonolyse und reduktive Aufarbeitung aus Vitamin D3 zugängliche Alkohol (II) wird zu dem Ketongemisch (III) oxidiert, wobei das trans‐Isomere bei weitem überwiegt.
ChemInform Abstract: A Novel Method for the Stereoselective Synthesis of β‐Aminoacid Derivatives via Tin(II) Carboxylic Thioester Enolates.
Authors: YAMASAKI N. , MURAKAMI M. , MUKAIYAMA T.
Published: May 2016

The ketene (I) reacts with the tin mercaptide (II) to yield the thiolester enolate (III), which couples with the imines (IV) in the presence of tin triflate (V), giving the isomeric adducts (VI) and (VII).
ChemInform Abstract: A New Route to Perhydro‐ and Tetrahydro‐furo[2,3‐b]furans via Radical Cyclisation.
Authors: PEZECHK M. , BRUNETIERE A. P. , LALLEMAND J. Y.
Published: May 2016

After bromination of dihydrofuran (I) and conversion of the dibromide (II) into the ethers (IV), the isomers (V) and (VI) are obtained by radical cyclization.
ChemInform Abstract: Alkylation of Substituted Pyrrole Dianions. Synthetic Studies Directed at the B/C Ring Systems of CC‐1065.
Authors: BRYSON T. A. , ROTH G. A. , LIU J.‐H.
Published: May 2016

The pyrrole derivatives (I) are substituted with 1,2‐dibromoethane (II) to yield (III).
ChemInform Abstract: A New Approach to the Carbapenam Nucleus through an Intramolecular N‐Heterocyclization.
Authors: DUMAS F. , D'ANGELO J.
Published: May 2016

The allyl‐azetidinone (I) is converted to the esters (III).
ChemInform Abstract: Photochemical Transformations of (E)‐1‐(2‐Arylidene‐1′‐phenylhydrazinyl)‐1,2‐dibenzoylalkenes.
Authors: PRATAPAN S. , SCARIA P. M. , BHATTACHARYYA K. , DAS P. K. , GEORGE M. V.
Published: May 2016

Die Photolyse der aus (I) und (II) zugänglichen Hydrazonyl‐alkene (III) führt zu den Pyrazolen (IV).
ChemInform Abstract: Selenonium Monoketoylides in the Synthesis of 4‐ and 5‐Spiro‐isoxazolidines.
Authors: MAGDESIEVA N. N. , SERGEEVA T. A.
Published: May 2016

The phenacylselenonium compound (I) is deprotonated and subsequently treated with nitrosobenzene to give the novel nitrone (II).
ChemInform Abstract: An Unusual Cleavage of 2,5‐Difluorobenzophenone.
Authors: CARR A. A. , HUBER E. W. , KANE J. M. , MILLER F. P.
Published: May 2016

2,5‐Difluorbenzophenon (I) reagiert mit dem Thiosemicarbazid (II) in Gegenwart von Alkali zu dem Triazolthion (III), das unabhängig aus (II) über das Benzoyl‐Derivat (IV) erhalten werden ′ kann.
ChemInform Abstract: 4‐Alkenyl‐1,2,3‐thiadiazoles.
Authors: HANOLD N. , KALBITZ H. , PIEPER M. , ZIMMER O. , MEIER H.
Published: May 2016

The synthesis of the title compounds (VI) and (X) [in part obtained as mixtures with the (Z)‐isomers.
ChemInform Abstract: Sensitized Photooxygenation. Part 2. Solvent Effects in the Reaction of Singlet Oxygen with 3,4‐Dihydro‐6‐methyl‐2H‐pyran‐5‐carboxylic Acid Ethyl Ester.
Authors: CHAN Y.‐Y. , ZHU C. , LEUNG H.‐K.
Published: May 2016

The product ratio of the photooxygenation of the dihydropyran (I) to the hydroperoxides (II) or (III) depends on the solvents and the sensitizers.
ChemInform Abstract: Pyridine Compounds from Etacrynic Acid.
Authors: GOERLITZER K. + , DUEWEL W. +
Published: May 2016

Durch Zusammenschmelzen von Etacrynsäure (II) mit den vinylogen Amiden (I) werden die Pyridine (IV) erhalten.
ChemInform Abstract: Synthesis and Spectral Studies of Alcohols of Fluorene, Isomeric Azafluorenes and Indenoquinoline.
Authors: SARKAR S. K. , PLESHAKOV V. G. , GAIVORONSKAYA L. A. , ZAKHAROV V. F. , MURUGOVA L. A. , PROSTAKOV N. S.
Published: May 2016

The tertiary alcohols (III), (V), (VII), (IX) and (XI) are prepared by reaction of the ketones (I), (IV), (VI), (VIII) and (X) with the Grignard reagents (II).
ChemInform Abstract: Syntheses of 1,3‐Disubstituted Imidazo[1,5‐a]pyridines.
Authors: KRAPCHO A. P. , POWELL J. R.
Published: May 2016

The bis(pyridyl)imines (Ia) and (Ib) react with LDA and benzophenone (II) to give the imidazopyridines (III) and benzhydrole (IV).
ChemInform Abstract: Synthesis of Pyrazolo[4′,3′:5,6]pyrido[1,2‐a]benzimidazole Derivatives and Study of Their Fluorescence Properties.
Authors: RAJADHYAKSHA D. D. , RANGNEKAR D. W.
Published: May 2016

In einer Vilsmeier‐Haack‐Reaktion wird das Pyridobenzimidazol (I) über die Zwischenprodukte (II) und (III) zu dem Dinitril (V) umgesetzt.
ChemInform Abstract: Synthesis of Oxazolo[4′,5′:5,6]pyrido[1,2‐a]benzimidazole Derivatives and Study of Their Fluorescent Properties.
Authors: RANGNEKAR D. W. , RAJADHYAKSHA D. D.
Published: May 2016

Als Schlüsselprodukt zur Synthese der im Titel genannten Verbindungen wird das Pyridobenzimidazol (III) durch Reduktion der Azoverbindung (II) hergestellt und mit Mono‐ und Dicarbonsäureestern zu den Oxazolen (IV) und (V) cyclisiert.
ChemInform Abstract: Nucleophilic Substitutions on Bromotriazolopyridines. An Improved Route to 2,6‐Disubstituted Pyridines and to 1,3‐Disubstituted Isoquinolines.
Authors: ABARCA B. , BALLESTEROS R. , JONES G. , MOJARRAD F.
Published: May 2016

The lithio triazolopyridines (I) are brominated to give (II) and then substituted with nucleophilic reagents yielding the derivatives (IV).