bluuebunny/crossref_metadata_2025 huggingface dataset:
Geometrical Breakdown Approach to interpretation of depositional sequences
Authors: Aali Masoud , Richards Bill , Nedimović Mladen R. , Maselli Vittorio , Gibling Martin R.
Published: August 2021

Seismic and sequence stratigraphic analyses are important methodologies for interpreting coastal and shallow-marine deposits. Though both methods are based on objective criteria, terminology for reflection/stratal stacking is widely linked to eustatic cycles, which does not adequately incorporate factors such as differential subsidence, sediment supply, and autogenic effects. To reduce reliance on model-driven interpretations, we developed a Geometrical Breakdown Approach (GBA) that facilitates interpretation of horizon-bound reflection packages by systematically identifying upward-downward and landward-seaward trajectories of clinoform inflection points and stratal terminations, respectively. This approach enables a rigorous characterization of stratal surfaces and depositional units. The results are captured in three-letter acronyms that provide an efficient way of recognizing repetitive stacking patterns through discriminating reflection packages objectively to the maximum level of resolution provided by the data. Comparison of GBA with selected sequence stratigraphic models that include three and four systems tracts and the accommodation succession approach shows that the GBA allows a greater level of detail to be extracted, identifying key surfaces with more precision and utilizing more effectively the fine-scale resolution provided by the input seismic data. We tested this approach using a synthetic analogue model and field data from the New Jersey margin. The results demonstrate that the geometric criteria constitute a reliable tool for identifying systems tracts and provide an objective and straightforward method for practitioners at all levels of experience.
Supplemental Material: Geologic framework of Mount Diablo, California
Authors: Graymer R.W. , Langenheim V.E.
Published: August 2021

Geologic Map of Mount Diablo
Supplemental Material: Miocene stratigraphy and structure of the East Bay Hills, California
Authors: Wagner J. Ross , al. et
Published: August 2021

Supplemental Materials: 1: Correlation of the Monterey and San Pablo Groups in the East Bay; 2: Ages and correlations of the Contra Costa and San Pablo; 3: The Indian Valley member of the Moraga Formation; 4: Map distribution of the Upper San Pablo Group and Lower Orinda member and inferred displacement across the Divide Ridge fault zone; 5: Analytical data for radiometric dates; and 6: Plate 1: Geologic map of Miocene rocks of the East Bay.
Delayed neuromonitoring alarm after scoliosis correction in Lenke type 4 adolescent idiopathic scoliosis
Authors: Yoshida Go , Hasegawa Tomohiko , Yamato Yu , Matsuyama Yukihiro
Published: August 2021

A 12-year-old girl underwent surgery for Lenke type 4 adolescent idiopathic scoliosis. After scoliosis correction, the transcranial motor-evoked potential (Tc-MEP) showed no alarm. However, the Tc-MEP amplitude had declined ~10 min after correction, with a normal blood pressure (BP) and body temperature and without any technical monitoring errors. Therefore, we suspected indirect spinal cord ischaemia because of the delayed true-positive Tc-MEP alarm. All the strong corrections made loss of Tc-MEP and all the correction releases made recovers of waveform. Finally, a weak correction was performed, and the Tc-MEP amplitude was recovered. Because transient spinal cord ischaemia due to correction of triple curves may cause a delayed monitoring alarm, the monitoring team should frequently check Tc-MEP after these manoeuvres. This patient had no neurological deficits and was considered to be a rescue case.
Case of acute onset ataxia caused byKlebsiella pneumoniaesepsis with the appearance of anti-GD1b antibody
Authors: Yamada Shigeo , Umeya Takashi
Published: August 2021

Various disorders can cause acute onset ataxia including those that have toxic/metabolic, traumatic, neoplastic, vascular, demyelinating/dysmyelinating, infectious, postinfectious and genetic features. We present a case of postseptic acute ataxia. A 72-year-old woman was diagnosed with septic shock secondary to acute obstructive suppurative cholangitis. A blood sample for bacterial culture was positive forKlebsiella pneumoniae. Thus, we initiated antibiotics and intravenous immunoglobulin therapies to control the infection. We later added extracorporeal endotoxin removal with a polymyxin B immobilised fibre cartridge for endotoxin shock. The patient’s condition improved soon after endotoxin removal. Mildly slurred and explosive speech with limb and truncal ataxia, which improved gradually, developed shortly afterwards. Serum samples obtained on day 15 after admission were positive for anti-GD1b IgG antibody. The clinical course of monophasic illness with good recovery, neurological findings and the appearance of anti-GD1b antibody suggest that this case is a variant of Miller-Fisher syndrome.
Experience of low-dose dexamethasone use in the respiratory management of ichthyosis prematurity syndrome
Authors: Henderson Davina , Murphy Claire A , O'Dea Mary , Boyle Michael A
Published: August 2021

Ichthyosis prematurity syndrome (IPS) is a rare disorder of autosomal recessive inheritance. The cardinal features include prematurity, vernix like hyperkeratosis, eosinophilia and neonatal asphyxiation. This case report discusses the presentation and management of IPS. We aim to characterise the common features, the spectrum of disease within a single family and discuss a potential role for low-dose dexamethasone in the management of ventilator-dependent patients with IPS.
Patient with systemic emboli in the setting ofKlebsiella oxytocatricuspid valve endocarditis and patent foramen ovale treated with NobleStitch and AngioVac
Authors: Leso John , Al-Ahmad Majd , Hand Drinnon O
Published: August 2021

A 34-year-old man with a medical history of injection drug use presented with 2 weeks of weakness, nausea, vomiting and septic shock secondary to infective endocarditis of a native tricuspid valve. On admission, CT chest demonstrated multiple cavitary lesions as well as numerous small infarcts seen on MRI brain concerning for systemic septic emboli. Subsequent transthoracic echo with bubble study revealed a large patent foramen ovale (PFO). The patient later received surgical debulking of his tricuspid valve vegetation with AngioVac. Subsequently, PFO closure was performed with a NobleStitch device. The case presented here demonstrates the importance of having a high index of suspicion with right-sided endocarditis and the development of other systemic signs and symptoms. It also underscores the necessity of a multidisciplinary team of cardiologists, surgeons, infectious disease specialists and intensivists in the treatment of these complicated patients.
Strawberry pink blood: hypertriglyceridaemia and diabetic ketoacidosis secondary to poorly controlled type 2 diabetes mellitus
Authors: Tan Timothy Xin Zhong , Lim Steven Hoon Chin , Khoo Joan
Published: August 2021

A 54-year-old woman with insulin-requiring type 2 diabetes mellitus presented with acute shortness of breath and drowsiness on a background of polydipsia, weakness and significant weight loss. One year ago, she had decided to stop her insulin and other medications and adopt lifestyle modifications instead. Initial emergency department (ED) blood samples were highly lipaemic and appeared strawberry pink. She was eventually diagnosed with diabetic ketoacidosis (DKA) with severe hypertriglyceridaemia, intubated for airway protection, and managed with fluid resuscitation and intravenous insulin to good effect. We share an uncommon DKA presentation at the ED. History was limited as the patient was drowsy and minimally communicative. Physical examination was unremarkable. Blood investigations were also delayed in view of the need for additional centrifugation. These contributed to a paucity of information in the acute setting and resulted in a diagnostic challenge.
Acquired tracheoesophageal fistula in a pregnant patient with COVID-19 pneumonia on prolonged invasive ventilation
Authors: Cuaño Patricia Maria Gregoria Mina , Pilapil John Christopher Agsalud , Larrazabal Ramon Jr Bagaporo , Villalobos Ralph Elvi
Published: August 2021

A previously healthy pregnant woman was diagnosed with COVID-19 pneumonia and was subsequently intubated. Throughout the course of her illness, the patient was treated for recurrent bouts of pneumonia. A high-resolution chest and neck CT scan confirmed the presence of a tracheoesophageal fistula (TEF), which may have been caused by the presence of the overinflated endotracheal cuff, prolonged steroid use, hypoxic injury and possible direct injury of the tracheal mucosa from COVID-19 itself. A temporising procedure, involving tracheostomy with an extended-length tracheal tube, was performed. Unfortunately, the patient succumbed to infection prior to definitive repair. This case highlights the importance of keeping a high index of suspicion for tracheal injury in patients who experience prolonged periods of intubation. It also underlies the high morbidity and mortality rate associated with TEF, although being a rare disease.
Failure of OPHL type IIb due to undiagnosed Eagle syndrome
Authors: Verro Barbara , Saraniti Carmelo
Published: August 2021

A 52-year-old man with glottic-supraglottic tumour underwent open partial horizontal laryngectomy (OPHL) IIb. On the 12th day postoperative, laryngoscopy showed necrotic tissue at the level of pexy and an increased distance between tongue base and neoglottis; the neck CT showed cricoid arch rupture and rupture of the pexy. By re-examining the preoperative CT images, the ossification of stylohyoid ligament (Eagle syndrome) was detected and supposed as the possible cause of cricoid rupture due to its traction on the hyoid bone and therefore on the pexy. The stylohyoid ligaments were cut at their insertion on the hyoid bone and a tracheohyoidopexy was performed. Two months after surgery, the patient had only some swallowing impairments. This case represents a complication in OPHL II never reported in literature caused by an undiagnosed Eagle syndrome in preoperative, pointing out the importance to search for any anatomical anomaly that could jeopardise the success of the surgery.
Early use of Antibiotics for at Risk CHildren with InfluEnza (ARCHIE): protocol for a double-blind, randomised, placebo-controlled trial
Authors: Wang Kay , Carver Tricia , Tonner Sharon , Semple Malcolm G , Hay Alastair D , Moore Michael , Little Paul , Butler Christopher , Farmer Andrew , Perera Rafael , Yu Ly-Mee , Mallett Susan , Wolstenholme Jane , Harnden Anthony
Published: August 2021

Introduction

Influenza and influenza-like illness (ILI) create considerable burden on healthcare resources each winter. Children with pre-existing conditions such as asthma, diabetes mellitus and cerebral palsy are among those at greatest risk of clinical deterioration from influenza/ILI. The Antibiotics for at Risk CHildren with InfluEnza (ARCHIE) trial aims to determine whether early oral treatment with the antibiotic co-amoxiclav reduces the likelihood of reconsultation due to clinical deterioration in these ‘at risk’ children.

Methods and analysis

The ARCHIE trial is a double-blind, parallel, randomised, placebo-controlled trial. ‘At risk’ children aged 6 months to 12 years inclusive who present within the first 5 days of an ILI episode will be randomised to receive a 5-day course of oral co-amoxiclav 400/57 twice daily or placebo. Randomisation will use a non-deterministic minimisation algorithm to balance age and seasonal influenza vaccination status.

To detect respiratory virus infections, a nasal swab will be obtained from each participant before commencing study medication. To identify carriage of potential bacterial respiratory pathogens, we will also obtain a throat swab where possible.

The primary outcome is reconsultation in any healthcare setting due to clinical deterioration within 28 days of randomisation. We will analyse this outcome using log-binomial regression model adjusted for region, age and seasonal influenza vaccination status.

Secondary outcomes include duration of fever, duration of symptoms and adverse events. Continuous outcomes will be compared using regression analysis (or equivalent non-parametric method for non-normal data) adjusting for minimisation variables. Binary outcomes will be compared using χ2/Fisher’s exact test and log-binomial regression.

Ethics

The ARCHIE trial has been reviewed and approved by the North West-Liverpool East Research Ethics Committee, Health Research Authority and Medicines and Healthcare Products Regulatory Agency. Our findings will be published in peer-reviewed journals and disseminated via our study website (www.archiestudy.com) and links with relevant charities.

Trial registration numbers

ISRCTN70714783; Pre-results.
Qualitative study on mental health and well-being of Syrian refugees and their coping mechanisms towards integration in the UK
Authors: Paudyal Priyamvada , Tattan Mais , Cooper Maxwell J F
Published: August 2021

Objective

This study aimed to explore the mental well-being of Syrian refugees and identify their coping mechanisms and pathways towards integration into new communities.

Design

Qualitative study using in-depth semi-structured interviews.

Setting and participants

Adult Syrian refugees (>18 years old) currently residing in South East of England.

Results

12 participants (3 women and 9 men) took part in the study, all were born in Syria and the majority (n=9) were over 45 years of age. Our findings show that Syrian refugees face constant challenges as they try to integrate into a new society. Loss of and separation from loved ones as well as the nostalgia for the homeland were often cited as a source of psychological distress that created an overwhelming sense of sadness. Participants reported that they struggled for connectedness due to cultural difference and the problematic nature of rapidly formed migrant communities in their new setting. They believed in ‘being their own doctor’ and turning to faith, ritual and nature for healing and comfort. Taboo and stigma around mental health and language barriers were cited as barriers to accessing mental healthcare services.

Conclusion

Past experiences and present challenges frame Syrian refugees’ sense of well-being, impact use of healthcare and risk future mental health problems. It is hoped that this study will act as a catalyst for further research on this vulnerable group to promote integration, community support and culturally sensitive mental health services.
Adolescents’ beliefs, attitudes and social norms with regard to smoking and sports: a qualitative study
Authors: Olsen Ingri Grimnes , Garritsen Heike H , van de Goor Ien , Kunst Anton E , Rozema Andrea D
Published: August 2021

Objectives

The aim of this study is to explore the beliefs, attitudes and social norms of Dutch adolescents with regard to smoking and sports. In addition, we examine whether there are differences between adolescents at sports clubs with versus without an outdoor smoke-free policy (SFP).

Design

Qualitative design in the form of focus group interviews.

Setting

Focus group interviews (n=27) were conducted at 16 sports clubs in the Netherlands. Soccer, tennis, field hockey and korfball clubs were included. Focus group discussions were transcribed verbatim and analysed thematically using MAXQDA.

Participants

180 adolescents aged 13–18 years old were included in the study. All participants signed an informed consent form. For participants younger than 16 years, parental consent was required.

Results

With respect to smoking in relation to sports, participants had mostly negative beliefs (ie, smoking has a negative effect on health and sports performance), attitudes (ie, sports and smoking are activities that do not fit together; at sports clubs smoking is not appropriate), and social norms (ie, it is not normal to smoke at sports clubs). The same beliefs, attitudes and social norms were expressed by participants at both sports clubs with and without an outdoor SFP. However, argumentation against smoking was more detailed and more consistent among participants at sports clubs with an outdoor SFP.

Conclusion

Adolescents have negative beliefs, attitudes and social norms with regard to smoking in relationship to sports. Outdoor SFP at sports clubs might reinforce these negative associations. These findings point to the potential importance of sports in the prevention of adolescent smoking.
Natural history of histologically confirmed high-grade cervical intraepithelial neoplasia during pregnancy: meta-analysis
Authors: Chen Cheng , Xu Yu , Huang Wu , Du Yi , Hu Cui
Published: August 2021

Objectives

This study aimed to conduct a meta-analysis of estimates of the natural history of high-grade cervical intraepithelial neoplasia (CIN) during pregnancy.

Setting

Studies examining the clinical courses of histologically confirmed high-grade CIN during pregnancy.

Participants

We searched PubMed, Web of Science and Embase for eligible studies. Studies were included if they reported the data regarding the natural history of histologically confirmed high-grade CIN during pregnancy. Final estimates were from the meta-analysis of 10 eligible studies.

Primary outcome measures

The regression rate, persistence rate and progression rate of histologically proven untreated high-grade CIN during pregnancy.

Results

A total of 10 original studies were included in this meta-analysis. During pregnancy, the regression rate, persistence rate and progression rate of high-grade CIN were 40% (95% CI 35% to 45%), 59% (95% CI 54% to 64%) and 1% (95% CI 0% to 2%), respectively. There was moderate heterogeneity among the studies. The results of the subgroup meta-analysis show that the pooled rates of regression and persistence during pregnancy were 59% (95% CI 54% to 65%) and 40% (95% CI 35% to 45%) for CIN2, and 29% (95% CI 25% to 33%) and 70% (95% CI 65% to 73%) for CIN3.

Conclusions

During pregnancy, the majority of histologically confirmed high-grade CIN would be persistent or regressed to lower grade CIN or normal. However, it is still worth noting that a small percentage of high-grade CIN would progress to cervical cancer during pregnancy.
Development and pilot testing of survey items to assess the culture of value and efficiency in hospitals and medical offices
Authors: Sorra Joann , Zebrak Katarzyna , Yount Naomi , Famolaro Theresa , Gray Laura , Franklin Martha , Smith Scott Allan , Streagle Suzanne
Published: August 2021

Background

Given rising costs and changing payment models, healthcare organisations are increasingly focused on value and efficiency. The goal of our study was to develop survey items to assess clinician and staff perspectives about the extent to which the organisational culture in hospitals and medical offices supports value and efficiency.

Methods

Development began with a literature review and interviews with experts and clinicians and staff from hospitals and medical offices. We identified key areas of value and efficiency culture, drafted survey items and conducted cognitive testing. Using purposive sampling to select sites, the 36-item surveys were pilot tested in 47 hospitals and 96 medical offices. Psychometric analysis was conducted on data from 3951 hospital respondents (42% response) and 1458 medical office respondents (63% response).

Results

Factor loadings, multilevel confirmatory factor analysis model fit and reliability estimates were acceptable for the 13 items grouped into 4 composite measures: Empowerment to Improve Efficiency (3 items), Efficiency and Waste Reduction (3 items), Patient Centeredness and Efficiency (3 items) and Management Support for Improving Efficiency and Reducing Waste (4 items). All composite measures were significantly intercorrelated and related to the four Overall Ratings of Healthcare Quality, indicating adequate conceptual convergence among the measures. Eight items assessing Experiences With Activities to Improve Efficiency were also included.

Conclusion

We developed psychometrically sound survey items measuring value and efficiency culture. When added to the Agency for Healthcare Research and Quality Surveys on Patient Safety Culture, the item sets extend those surveys by assessing additional dimensions of organisational culture that affect care delivery. Healthcare organisations can use these item sets to assess how well their organisational culture supports value and efficiency and identify areas for improvement.
Prevalence of internet addiction among college students in the Indian setting: a systematic review and meta-analysis
Authors: Joseph Jaison , Varghese Abin , VR Vijay , Dhandapani Manju , Grover Sandeep , Sharma Suresh , Khakha Deepika , Mann Sucheta , Varkey Biji P
Published: August 2021

Background

The internet is an integral part of everyone’s life. College going adolescents are highly vulnerable to the misuse of the internet.

Aims

To estimate the pooled prevalence of internet addiction (IA) among college students in India.

Methods

Literature databases (PubMed, Web of Science, Scopus, EMBASE, PsycINFO and Google Scholar) were searched for studies assessing IA using the Young Internet Addiction Test (Y-IAT) among adolescents from India, published in the English language up to December 2020. We included studies from 2010 to 2020 as this is the marked era of momentum in wireless internet connectivity in India. The methodological quality of each study was scored, and data were extracted from the published reports. Pooled prevalence was estimated using the fixed-effects model. Publication bias was evaluated using Egger’s test and visual inspection of the symmetry in funnel plots.

Results

Fifty studies conducted in 19 states of India estimated the prevalence of IA and the overall prevalence of IA as 19.9% (95% CI: 19.3% to 20.5%) and 40.7% (95% CI: 38.7% to 42.8%) based on the Y-IAT cut-off scores of 50 and 40, respectively. The estimated prevalence of severe IA was significantly higher in the Y-IAT cut-off points of 70 than 80 (12.7% (95% CI: 11.2% to 14.3%) vs 4.6% (95% CI: 4.1% to 5.2%)). The sampling method and quality of included studies had a significant effect on the estimation of prevalence in which studies using non-probability sampling and low risk of bias (total quality score ≥7) reported lower prevalence. The overall quality of evidence was rated as ‘moderate’ based on the Grading of Recommendations Assessment, Development and Evaluation criteria.

Conclusions

Our nationally representative data suggest that about 20% to 40% of college students in India are at risk for IA. There is a need for further research in the reconsideration of Y-IAT cut-off points among Indian college students.

PROSPERO registration number

CRD42020219511.
Collecting affect: emotion and empathy in World War II photographs and drawings of plastic surgery
Authors: Slobogin Christine
Published: August 2021

This article compares drawings by Diana ‘Dickie’ Orpen (1914–2008) with photographs by Percy Hennell (1911–1987); both of their oeuvres depict plastic reconstructive surgeries from World War II in Britain. Through visual analysis, personal experience and interviews with archivists who have worked with the collections, this article aims to determine the affective effects of these drawings and photographs. I argue that Hennell’s images are the more affective and subjective objects, even though their original purpose was objective and scientific. This article asks why Hennell’s photographs of plastic surgery produce such a vehement emotive response.

Investigating Hennell’s use of colour, his compositional choices and the unexpected visual particulars of the operating theatre that he captures—all of which ‘collect affect’ within the photo-archival object—this analysis uses a phenomenological framework to determine the limitations and strengths of two very different styles and mediums of World War II surgical imagery.

Beyond establishing which group of images is more affecting, this article also shows why it is empathy that is the most fitting emotional description of the typical responses to Hennell’s photographs. This type of visual analysis of empathic images can be applied to objects-based medical humanities pedagogy that encourages empathy—historical empathy as well as empathy in the present day—for surgical practitioners and trainees.
After the madhouses: the emotional politics of psychiatry and community care in the UK tabloid press 1980–1995
Authors: Sidi Leah
Published: August 2021

The deinstitutionalisation of mental hospital patients made its way into UK statutory law in 1990 in the form of the NHS and the Community Care Act. The Act ushered in the final stage of asylum closures moving the responsibility for the long-term care of mentally ill individuals out of the NHS and into the hands of local authorities. This article examines the reaction to the passing of the Act in two major tabloid presses,The SunandThe Daily Mirror, in order to reveal how community care changed the emotional terrain of tabloid storytelling on mental health. Reviewing an archive of 15 years of tabloid reporting on mental illness, I argue that the generation of ‘objects of feeling’ in the tabloid media is dependent on the availability of recognisable and stable symbols. Tabloid reporting of mental illness before 1990 reveals the dominance of the image of the asylum in popular understandings of mental illness. Here the asylum is used to generate objects of hatred and disgust for the reader, even as it performs a straightforward othering and distancing function. In these articles, the image of the asylum and its implicit separation of different types of madness into categories also do normative gender work as mental illness is represented along predictable gendered stereotypes. By performing the abolition of asylums, the 1990 Act appears to have triggered a dislodging of these narrative norms in the tabloid press. After 1990, ‘asylum stories’ are replaced with ‘community care stories’ which contain more contradictory and confusing clusters of feeling. These stories rest less heavily on gendered binaries while also demonstrating a near-frantic desire on the part of the mass media for a return of institutional containment. Here, clusters of feeling becoming briefly ‘unstuck’ from their previous organisations, creating a moment of affective flux.
The times and spaces of transplantation: queercrip histories as futurities
Authors: McCormack Donna
Published: August 2021

With a focus on Larissa Lai’sThe Tiger Flu, this article explores how transplantation is part of the ongoing transformation of being in a body that is of the world. That is, it examines how we may require other ways of thinking bodies as constituted by histories, spaces and times that may be ignored in the biomedical arena.The Tiger Flu, I argue, calls for an intra- and inter-connected way of thinking how we treat bodies, and thereby ways of working with bodies affected by environmental disasters (both acute and ongoing capitalist and colonial projects), multiple selves and time as more than linear. I turn to queercrip as a way of defying a curative imaginary that dominates transplantation and in so doing examine the colonial, capitalist violence of present day living. I move through Eve Hayward’s and Karen Barad’s work to examine how the cut of transplantation is a transformation, as integral to the ongoing experience of having a body in the world and yet potentially unique in its force of bringing inter- and intra-relatedness to the fore of one’s existence. Rather than sick or cured, I argue that transplantation is a transformation that captures our bodily changes, how the environment constitutes the self, how parts may feel integral to the self or easily disposed of, how viscera may tie us to others, and how the future may only be forged through a re-turn to the past (of the donor and a pre-transplant self). Transplantation is not about loss of self or gaining of an other, but rather about rendering apparent our multispecies, multiworld ties, and thus how we are bound by the histories we forge and the futures we re-member.
Automated emergent large vessel occlusion detection by artificial intelligence improves stroke workflow in a hub and spoke stroke system of care
Authors: Elijovich Lucas , Dornbos III David , Nickele Christopher , Alexandrov Andrei , Inoa-Acosta Violiza , Arthur Adam S , Hoit Daniel
Published: August 2021

Background

Emergent large vessel occlusion (ELVO) acute ischemic stroke is a time-sensitive disease.

Objective

To describe our experience with artificial intelligence (AI) for automated ELVO detection and its impact on stroke workflow.

Methods

We conducted a retrospective chart review of code stroke cases in which VizAI was used for automated ELVO detection. Patients with ELVO identified by VizAI were compared with patients with ELVO identified by usual care. Details of treatment, CT angiography (CTA) interpretation by blinded neuroradiologists, and stroke workflow metrics were collected. Univariate statistical comparisons and linear regression analysis were performed to quantify time savings for stroke metrics.

Results

Six hundred and eighty consecutive code strokes were evaluated by AI; 104 patients were diagnosed with ELVO during the study period. Forty-five patients with ELVO were identified by AI and 59 by usual care. Sixty-nine mechanical thrombectomies were performed.

Median time from CTA to team notification was shorter for AI ELVOs (7 vs 26 min; p<0.001). Door to arterial puncture was faster for transfer patients with ELVO detected by AI versus usual care transfer patients (141 vs 185 min; p=0.027). AI yielded a time savings of 22 min for team notification and a 23 min reduction in door to arterial puncture for transfer patients.

Conclusions

AI automated alerts can be incorporated into a comprehensive stroke center hub and spoke system of care. The use of AI to detect ELVO improves clinically meaningful stroke workflow metrics, resulting in faster treatment times for mechanical thrombectomy.
The effect of tamping conditions on undrained shear strengths of a non-plastic sandy silt tailings
Authors: Reid David , Fanni Riccardo , DiDonna Peter
Published: August 2021

A series of direct simple shear (DSS) tests were carried out on a non-plastic sandy silt lead−zinc−silver tailings to develop a relationship between undrained shearing behaviour and density for contractive states. The critical state line was also obtained through triaxial compression tests to enable the DSS tests to be viewed in a critical state framework and allow comparison with in situ testing. It was found that the gravimetric water content (GWC) used to tamp the specimens had a significant effect on the resulting undrained strengths when attempting to achieve dense states — with higher GWC giving lower strength at a given density than a lower GWC. Intact and slurry deposited (SD) samples were also tested to access denser states without inducing tamping-related stresses. These showed a more consistent trend with the loose-tamped specimens, and with other data from the literature. Plausible explanations as to the causes of the increased strength of dense-tamped samples were obtained through estimating potential preconsolidation stresses and “locked in” horizontal stresses that may occur from dense tamping. The importance of these observations on the development of density−strength profiles in engineering practice was outlined.
Bud dormancy pattern, chilling requirement, and cold hardiness inVitis viniferaL. ‘Chardonnay’ and ‘Riesling’
Authors: Rahemi Alireza , Fisher Helen , Dale Adam , Taghavi Toktam , Kelly John
Published: August 2021

In recent years, new vineyards have been established in southwestern Ontario. The open water of Lake Erie provides some winter protection for Vitis hybrids and winter-hardy Vitis vinifera L. cultivars in this area. However, winter damage is possible when vines are grown distant from the open water or when lakes are frozen. To better understand the risks to winter survival, the dormancy and chilling phenology were studied over three winters from 2013–2016. Ten dormant canes of two V. vinifera cultivars, ‘Chardonnay’ and ‘Riesling’, were collected weekly from 1 September until 30 March from the mature vines in a commercial vineyard located at St. Williams (Ontario). The canes defoliated in early October, and the endodormancy was completed by the end of December. The cumulative chilling hours (0–7.2 °C) from defoliation until the completion of endodormancy were averaged 606 hours for ‘Chardonnay’ and 665 hours for ‘Riesling’. ‘Chardonnay’ buds were slightly less hardy than ‘Riesling’ to cold temperatures, with a threshold of about −24 °C for ‘Chardonnay’ and −25 °C for ‘Riesling’. Most primary buds of both cultivars died after 16 February 2015, and more than half died after 12 February 2014, due to severe low temperatures of −33.1 and −26 °C, respectively.
Effects of clipping frequency on tiller development of crested wheatgrass and hybrid bromegrass at vegetative and reproductive stages
Authors: Fan Ru-Yue , MacTaggart David , Wang Hu , Chibbar Ravindra N. , Li Qing Feng , Biligetu Bill
Published: August 2021

Information on the tiller development of hybrid bromegrass (Bromus inermis × Bromus riparius) is limited. The objective of this study was to evaluate the effect of clipping frequency at the vegetative and reproductive stages on the tiller development and concentrations of sugars of c.v ‘AC Knowles’ hybrid bromegrass compared with c.v ‘Kirk’ crested wheatgrass (Agropyron cristatum L.). This experiment was conducted in a greenhouse using the tillers of the vernalized plants dug from the field. The experimental design was a randomized complete block design (RCBD). Grasses were clipped once or four times at either vegetative or reproductive stage. Regardless of the growth stage, four clippings reduced the tiller number of hybrid bromegrass by 25.9% compared with the undefoliated control, while single clipping had no impact. The four clippings had no impact on the tiller number of crested wheatgrass, while single clipping increased its tiller number on average by 50.4% at both growth stages. Crested wheatgrass produced 16.6% more tillers than hybrid bromegrass under the single clipping. The two grass species had a similar number of axillary buds under different clipping treatments. The axillary bud size of crested wheatgrass was larger than hybrid bromegrass. All axillary buds were viable under the two clipping treatments for both grasses. Four clippings significantly decreased the stem base glucose concentration of the two grasses and the root sucrose concentration of crested wheatgrass. Hybrid bromegrass was less tolerant to frequent clippings than crested wheatgrass. Therefore, intensive grazing of hybrid bromegrass pasture may result in a thin stand.
Lattice parameters and electronic bandgap of orthorhombic potassium sodium niobate K$$_{0.5}$$Na$$_{0.5}$$NbO$$_{3}$$ from density-functional theory
Authors: Bidaraguppe Ramesh Nithin , Schmidt Falko , Schindlmayr Arno
Published: August 2021

We perform a theoretical analysis of the structural and electronic properties of sodium potassium niobate K$$_{1-x}$$

1
-
x

Na$$_{x}$$

x

NbO$$_{3}$$

3

in the orthorhombic room-temperature phase, based on density-functional theory in combination with the supercell approach. Our results for $$x=0$$

x
=
0

and $$x=0.5$$

x
=
0.5

are in very good agreement with experimental measurements and establish that the lattice parameters decrease linearly with increasing Na contents, disproving earlier theoretical studies based on the virtual-crystal approximation that claimed a highly nonlinear behavior with a significant structural distortion and volume reduction in K$$_{0.5}$$

0.5

Na$$_{0.5}$$

0.5

NbO$$_{3}$$

3

compared to both end members of the solid solution. Furthermore, we find that the electronic bandgap varies very little between $$x=0$$

x
=
0

and $$x=0.5$$

x
=
0.5

, reflecting the small changes in the lattice parameters.

Graphic abstract
A complete set of Lorentz-invariant wave packets and modified uncertainty relation
Authors: Oda Kin-ya , Wada Juntaro
Published: August 2021

We define a set of fully Lorentz-invariant wave packets and show that it spans the corresponding one-particle Hilbert subspace, and hence the whole Fock space as well, with a manifestly Lorentz-invariant completeness relation (resolution of identity). The position–momentum uncertainty relation for this Lorentz-invariant wave packet deviates from the ordinary Heisenberg uncertainty principle, and reduces to it in the non-relativistic limit.
Brain Computer Interfaces for Assisted Communication in Paralysis and Quality of Life
Authors: Chaudhary Ujwal , Chander Bankim Subhash , Ohry Avi , Jaramillo-Gonzalez Andres , Lulé Dorothée , Birbaumer Niels
Published: August 2021

The rapid evolution of Brain-Computer Interface (BCI) technology and the exponential growth of BCI literature during the past 20 years is a consequence of increasing computational power and the achievements of statistical learning theory and machine learning since the 1960s. Despite this rapid scientific progress, the range of successful clinical and societal applications remained limited, with some notable exceptions in the rehabilitation of chronic stroke and first steps towards BCI-based assisted verbal communication in paralysis. In this contribution, we focus on the effects of noninvasive and invasive BCI-based verbal communication on the quality of life (QoL) of patients with amyotrophic lateral sclerosis (ALS) in the locked-in state (LIS) and the completely locked-in state (CLIS). Despite a substantial lack of replicated scientific data, this paper complements the existing methodological knowledge and focuses future investigators’ attention on (1) Social determinants of QoL and (2) Brain reorganization and behavior. While it is not documented in controlled studies that the good QoL in these patients is a consequence of BCI-based neurorehabilitation, the proposed determinants of QoL might become the theoretical background needed to develop clinically more useful BCI systems and to evaluate the effects of BCI-based communication on QoL for advanced ALS patients and other forms of severe paralysis.
Investigation of transportation of nanofluid within non-equilibrium porous media
Authors: Rothan Yahya Ali
Published: August 2021

In this investigation, numerical modeling for the behavior of nanomaterial inside a porous zone with imposing Lorentz force has been illustrated. The working fluid is a mixture of H2O and CuO and due to concentration of 0.04, it is reasonable to use the homogeneous model. Two-temperature model for porous zone was employed in which new scalar for calculating temperature of solid region was defined. CVFEM has been applied to model this complex physics. Radiation terms were considered and their influence on Nu has also been considered. Verification with benchmark proves greater accuracy. Dispersing nanopowders helps the fluid to increase velocity and reduce the temperature of inner wall. Rise of Ra results in three strong eddies inside the zone which creates two thermal plumes and it reduces the temperature of square surface about 68%. With rise of Nhs, the power of counter-clockwise vortex reduces about 61.6% and inner wall becomes warmer about 33.3%. Raising the Ha makes thermal plume to vanish and cooling rate decreases about 46.6%. Augment of Nhs makes Nu to reduce about 5.08% while augment of Ra makes it to augment about 35.64%. Also, augmenting Ha makes Nu to decline about 56.45%.
STOCK MARKET PREDICTION IN BRICS COUNTRIES USING LINEAR REGRESSION AND ARTIFICIAL NEURAL NETWORK HYBRID MODELS
Authors: ATAMAN GÖRKEM , KAHRAMAN SERPIL
Published: August 2021

The BRICS (Brazil, Russia, India, China and South Africa) acronym was created by the International Monetary Foundation (IMF)–Group of Seven (G7) to represent the bloc of developing economies which crucially impact on the global economy by their potential economic growth. Most of the foreign direct investment are considering the stock markets of BRICS as the most attractive destination for foreign portfolio investment. This study aims to identify the relationship between macroeconomic variables and the stock market index values of BRICS and generate accurate predictions for index values by performing linear regression and artificial neural network hybrid models. Monthly data from January 2003 to December 2019 are used for the empirical study. The results indicate that a strong correlation exists between the stock market and macroeconomic variables in BRICS over time. The hybrid model is observed very accurate for index value prediction where the mean absolute percentage error (MAPE) value is 0.714% for the whole data set covering all BRICS countries data during the study period. Additionally, MAPE values for each of the BRICS countries are, respectively, obtained as 0.083%, 2.316%, 0.116%, 0.962% and 0.092%. Thus, the main findings of this study show that while neural network-integrated models have high performances for volatile stock market prediction, macroeconomic stabilization should be the priority of monetary policy to prevent the high volatility of stock markets.
New optical soliton solutions via two distinctive schemes for the DNA Peyrard–Bishop equation in fractal order
Authors: Ouahid Loubna , Abdou M. A. , Owyed S. , Kumar Sachin
Published: August 2021

The deoxyribonucleic acid (DNA) dynamical equation, which emerges from the oscillator chain known as the Peyrard–Bishop (PB) model for abundant optical soliton solutions, is presented, along with a novel fractional derivative operator. The Kudryashov expansion method and the extended hyperbolic function (HF) method are used to construct novel abundant exact soliton solutions, including light, dark, and other special solutions that can be directly evaluated. These newly formed soliton solutions acquired here lead one to ask whether the analytical approach could be extended to deal with other nonlinear evolution equations with fractional space–time derivatives arising in engineering physics and nonlinear sciences. It is noted that the newly proposed methods’ performance is most reliable and efficient, and they will be used to construct new generalized expressions of exact closed-form solutions for any other NPDEs of fractional order.
Systematic study of two-proton radioactivity half-lives based on a modified Gamow-like model
Authors: Liu Hong-Ming , Zou You-Tian , Pan Xiao , He Biao , Li Xiao-Hua
Published: August 2021

In this work, we systematically study the two-proton ([Formula: see text]) radioactivity half-lives of nuclei close to the proton drip line within a modified Gamow-like model. Using this model, the calculated [Formula: see text] radioactivity half-lives can well reproduce the experimental data. Moreover, we blackuse this model to predict the [Formula: see text] radioactivity half-lives of 22 candidates blackwhose [Formula: see text] radioactivity is energetically allowed or observed but not yet quantized in evaluated nuclear properties table NUBASE2016. blackThe predicted results are in good agreement with the ones obtained by using Gamow-like model, effective liquid drop model (ELDM), generalized liquid drop model (GLDM) as well as a four-parameter formula.
Multiple positive solutions for a p-Laplace Benci–Cerami type problem (1 < p < 2), via Morse theory
Authors: Vannella Giuseppina
Published: August 2021

Let us consider the quasilinear problem [Formula: see text] where [Formula: see text] is a bounded domain in [Formula: see text] with smooth boundary, [Formula: see text], [Formula: see text], [Formula: see text] is a parameter and [Formula: see text] is a continuous function with [Formula: see text], having a subcritical growth. We prove that there exists [Formula: see text] such that, for every [Formula: see text], [Formula: see text] has at least [Formula: see text] solutions, possibly counted with their multiplicities, where [Formula: see text] is the Poincaré polynomial of [Formula: see text]. Using Morse techniques, we furnish an interpretation of the multiplicity of a solution, in terms of positive distinct solutions of a quasilinear equation on [Formula: see text], approximating [Formula: see text].
NETWORK OF SCIENTIFIC CONCEPTS: EMPIRICAL ANALYSIS AND MODELING
Authors: PALCHYKOV VASYL , KRASNYTSKA MARIANA , MRYGLOD OLESYA , HOLOVATCH YURIJ
Published: August 2021

Concepts in a certain domain of science are linked via intrinsic connections reflecting the structure of knowledge. To get a qualitative insight and a quantitative description of this structure, we perform empirical analysis and modeling of the network of scientific concepts in the domain of physics. To this end, we use a collection of manuscripts submitted to the e-print repository arXiv and the vocabulary of scientific concepts collected via the ScienceWISE.info platform and construct a network of scientific concepts based on their co-occurrences in publications. The resulting complex network possesses a number of specific features (high node density, dissortativity, structural correlations, skewed node degree distribution) that cannot be understood as a result of simple growth by several commonly used network models. We show that the model based on a simultaneous account of two factors, growth by blocks and preferential selection, gives an explanation of empirically observed properties of the concepts network.
Modern compressive tomography for quantum information science
Authors: Teo Yong Siah , Sánchez-Soto Luis L.
Published: August 2021

This review serves as a concise introductory survey of modern compressive tomography developed since 2019. These are schemes meant for characterizing arbitrary low-rank quantum objects, be it an unknown state, a process or detector, using minimal measuring resources (hence compressive) without any a priori assumptions (rank, sparsity, eigenbasis, etc.) about the quantum object. This paper contains a reasonable amount of technical details for the quantum-information community to start applying the methods discussed here. To facilitate the understanding of formulation logic and physics of compressive tomography, the theoretical concepts and important numerical results (both new and cross-referenced) shall be presented in a pedagogical manner.
Gamification-as-Innovation: A Review
Authors: AlSaad Fatemah M. , Durugbo Christopher M.
Published: August 2021

Gamification is a paradigm and process innovation premised on applying game mechanics to non-game settings with benefits of creative games designs and disruptive effects challenging conventional learning approaches. The purpose of this study is to review the literature on gamification-as-innovation. Applying the systematic review methodology, this study examines 96 articles and identifies developments in gamification-as-innovation in literature. Insights from the review suggests three main perspectives on gamification-as innovation in processes that reveal problems (investigation), stimulate novel behavior (induction) or transform processes (intervention) for improved effectiveness and engagement. The review also captures the state-of-the-art in gamification research underscoring advances in multi-level models, strategic initiatives and digital platforms. The review concludes by highlighting future research directions that advance gamification scholarship and practice.