bluuebunny/crossref_metadata_2025 huggingface dataset:
Risk Factors for Baseball-Related Arm Injuries: A Systematic Review
Authors: Agresta Cristine E. , Krieg Kevin , Freehill Michael T.
Published: February 2019

Background:

Contributing factors for arm injuries among baseball players have been described. However, no review has systematically identified risk factors with findings from prospective cohort studies.

Purpose:

To systematically review prospective cohort studies that investigated risk factors for arm injury among baseball players.

Study Design:

Systematic review; Level of evidence, 3.

Methods:

Electronic databases were searched for relevant English-language studies. Titles, abstracts, and full-text articles were screened by 2 blinded reviewers to identify only prospective cohort studies and randomized controlled trials. Two independent investigators screened each article for appropriate criteria.

Results:

Fourteen prospective articles were selected for this review. Youth, high school, and professional baseball players (N = 2426) were pooled, and 43 risk factors were assessed in relation to general arm, shoulder, and elbow injuries. All studies evaluated players for at least 1 season. Deficits in preseason shoulder range of motion and strength were significant risk factors for general arm or shoulder injury among high school and professional players. Elbow and shoulder varus torque at peak external shoulder rotation during pitching, high pitch velocity, and shoulder rotational and flexion deficits were risk factors for elbow injuries among professional pitchers. Pitching >100 innings in 1 year, being aged 9 to 11 years, being a pitcher or catcher, training >16 hours per week, and having a history of elbow pain were significant risk factors for elbow injury among youth players.

Conclusion:

History of elbow pain and age had a high risk of associated elbow injury among youth players. Training or pitching load also increased elbow injury risk for youth athletes. Loss of shoulder range of motion appears to increase risk for elbow injury among professional athletes. Single time-point data collections per season, studies with the same sample population, and studies with self-reported injury and risk factor data may limit the interpretation of these findings. Health care professionals should use caution when assessing injury risk during evaluation and making decisions about the training workload and playing time of baseball players.
Communication Activities in the 21st Century Business Environment
Authors: Cyphert Dale , Holke-Farnam Corrine , Dodge Elena N. , Lee W. Eric , Rosol Sarah
Published: February 2019

Effective undergraduate instruction requires accurate knowledge of professional communication practices and employer expectations, but ongoing contradictions between academic and professional expectations reflect historical, rhetorical, and pedagogical causes for inaccurate presumptions. Taking a customer service perspective, one business faculty revised its undergraduate goals in terms of empirically determined employer expectations. Interviewing professionals familiar with expectations of entry-level business graduates, the authors identified 10 communication activities, each comprising three to nine subtasks that constitute entry-level communication competencies. The results suggest a need to reconsider traditional curricular organization and instructional focus across the business curriculum to develop relevant skills across all business majors.
Global Disparities Between Pediatric Publications and Disease Burden From 2006 to 2015
Authors: Keating Elizabeth M. , Haq Heather , Rees Chris A. , Dearden Kirk A. , Luboga Samuel A. , Schutze Gordon E. , Kazembe Peter N.
Published: February 2019

There is a disproportionate burden of pediatric disease in low- and middle-income countries (LMICs); however, the proportion and relation of published articles to childhood disease burden in LMICs have not been assessed previously. This study aimed to determine whether published articles and disease topics from research conducted in LMICs in the most widely cited pediatric journals reflected the global burden of childhood disease. We reviewed all articles published from 2006 to 2015 in the 3 pediatric journals with the highest Eigenfactor scores to identify studies conducted in the World Bank–designated LMICs. We abstracted study topic, design, purpose, country, and funding sources. We derived descriptive statistics, Fisher’s exact χ2 test, Monte Carlo estimates, and Spearman’s rank order coefficients. Of the 19 676 articles reviewed, 10 494 were original research articles. Of those, 965 (9.2%) were conducted in LMICs. Over the study period, the proportion of published articles originating from LMICs increased ( r2 = 0.77). Disease topics did not reflect the underlying burden of disease as measured in disability-adjusted life years (Spearman’s rank order coefficient = 0.25). Despite bearing the majority of the world’s burden of disease, articles from LMICs made up a small proportion of all published articles in the 3 pediatric journals with the highest Eigenfactor scores. The number of published articles from LMICs increased over the study period; nevertheless, the topics did not coincide with the burden of disease in LMICs. These discrepancies highlight the need for development of a research agenda to address the diseases that are the greatest threat to the majority of children worldwide.
A Review of fMRI Affective Processing Paradigms Used in the Neurobiological Study of Posttraumatic Stress Disorder
Authors: Negreira Alyson M. , Abdallah Chadi G.
Published: February 2019

Posttraumatic stress disorder is a chronic and debilitating psychiatric disorder with a complex clinical presentation. The last two decades have seen a proliferation of literature on the neurobiological mechanisms subserving affective processing in posttraumatic stress disorder. The current review will summarize the neuroimaging results of the most common experimental designs used to elucidate the affective signature of posttraumatic stress disorder. From this summary, we will provide a heuristic to organize the various paradigms discussed and report neural patterns of activations using this heuristic as a framework. Next, we will compare these results to the traditional functional neurocircuitry model of posttraumatic stress disorder and discuss biological and analytic variables which may account for the heterogeneity within this literature. We hope that this approach may elucidate the role of experimental parameters in influencing neuroimaging findings.
Everyday life experiences of spouses of patients who suffer from pulmonary arterial hypertension or chronic thromboembolic pulmonary hypertension
Authors: Ivarsson Bodil , Sjöberg Trygve , Hesselstrand Roger , Rådegran Göran , Kjellström Barbro
Published: February 2019

Introduction

Spouses play a crucial role, both physically and psychologically, for patients with pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH). Our aim was to investigate the spouse's experiences when living with a partner diagnosed with PAH or CTEPH.

Methods

We used a qualitative interview study design based on open-ended questions analysed using qualitative content analysis.

Results

14 spouses were interviewed. Two categories that describe spouses' experiences of dealing with everyday life were identified: “Living in an insecure life situation” and “Providing and receiving information and support”. The experiences reported by the spouses were that their life situation was insecure, and that they had challenges in providing and receiving information and support. Most spouses also wanted and felt a need to be more involved in the care.

Conclusion

The spouses were only partly satisfied with their life situation. To support the spouse's participation, the PAH/CTEPH team should encourage the patient to bring their spouse along, and offer them the opportunity to participate in the contacts with healthcare and provide information on an individual family perspective.
Treatment response in COPD: does FEV1say it all? Apost hocanalysis of the CRYSTAL study
Authors: Kostikas Konstantinos , Greulich Timm , Mackay Alexander J. , Lossi Nadine S. , Aalamian-Mattheis Maryam , Nunez Xavier , Pagano Veronica A. , Patalano Francesco , Clemens Andreas , Vogelmeier Claus F.
Published: February 2019

The association between clinically relevant changes in patient-reported outcomes (PROs) and forced expiratory volume in 1 s (FEV1) in patients with chronic obstructive pulmonary disease (COPD) has rarely been investigated.

Using CRYSTAL, a 12-week open-label study in symptomatic, nonfrequently exacerbating patients with moderate COPD, we assessed at baseline the correlations between several PROs (Baseline Dyspnoea Index, modified Medical Research Council dyspnoea scale, COPD Assessment Test (CAT) and Clinical COPD Questionnaire (CCQ)), and between FEV1and PROs. Associations between clinically relevant responses in FEV1, CAT, CCQ and Transition Dyspnoea Index (TDI) at week 12 were also assessed.

Using data from 4324 patients, a strong correlation was observed between CAT and CCQ (rs=0.793) at baseline, with moderate or weak correlations between other PROs, and no correlation between FEV1and any PRO. At week 12, 2774 (64.2%) patients were responders regarding TDI, CAT or CCQ, with 583 (13.5%) responding using all three measures. In comparison, 3235 (74.8%) were responders regarding FEV1, TDI, CAT or CCQ, with 307 (7.1%) responding concerning all four parameters.

Increases in lung function were accompanied by clinically relevant improvements of PROs in a minority of patients. Our results also suggest that PROs are not interchangeable. Thus, the observed treatment success in a clinical trial may depend on the selected parameters.
Exploiting temporal-spatial patterns of informal settlements using GIS and remote sensing technique: a case study of Jimma city, Southwestern Ethiopia
Authors: Abebe Misgana Secho , Derebew Kiros Tsegaye , Gemeda Dessalegn Obsi
Published: February 2019

Background

Temporal change detection of informal settlement was conducted using geographic information system and remote sensing in order to evaluate the land use land cover change (LULCC) in Jimma city, southwestern Ethiopia. We analyzed the LULCC since 1997 using Landsat imagery of 1997, and aerial photography of 2007 and 2017. Qualitative and quantitative data was also collected from city residents by using structured questionnaires focusing on peoples’ perceptions to understand the pattern of informal settlements in the study area. Maximum likelihood supervised classification methods was employed to create the signature class of the five land cover classes: built up, vegetation, barren land, open land and agricultural land.

Results

The results indicated that the informal settlement has been increased in the peripheries from 29% in 1997, 37% in 2007 and 41% in 2017. This study focuses on the continued transformation of various land uses into informal settlements, causing encroachment on agricultural and open land particularly in the city periphery. The unprecedented population growth and unplanned development activities in urban areas results in urban agglomeration, which increase the price of land market for construction. This implies that rapid population growth, shortage of formal housing and unaffordable cost of formal housing for urban dwellers contributed to informal settlements.

Conclusions

Increasing urbanization and rapid population growth are often associated with the development of urban informal settlements. Informal settlements and urban informality are the common problems particularly in the periphery of Jimma city. These results can be used as a basis for informal settlement assessment in other cities in the country and beyond.
Mobile Device Applications for Electronic Patient Portals in Oncology
Authors: Pho Kelvin K. , Lu Rong , Gates Samantha , Cai Jennifer , Xie Donglu , Xie Yang , Lee Simon J. Craddock , Gerber David E.
Published: February 2019

PURPOSE

Mobile devices provide individuals with rapid and frequent access to electronic patient portals. We investigated how oncology patients use this technology to review test results and communicate with providers.

PATIENTS AND METHODS

We performed a retrospective study of patients enrolled in the MyChart electronic health portal associated with the Epic electronic medical record at the Harold C. Simmons Comprehensive Cancer Center from 2012 to 2017. We recorded type of portal access according to year and patient characteristics. Associations among patient characteristics and types of portal access were tested using Mann-Whitney U test, χ2 test, and linear Gaussian regression models.

RESULTS

Since the availability of a mobile device application in 2012, 2,524 patients with cancer accessed MyChart from a mobile device at least once, which accounted for 291,526 mobile log-ins. The number of patients with MyChart mobile application log-ins increased from 4% in 2012 to 13% in 2017 ( P = .004). Among these patients, the median proportion of log-ins that occurred through mobile device use increased from 22% to 72% during this time period ( P < .001). Mobile access occurred more frequently among younger ( P < .001), black ( P = .002), and Hispanic ( P = .004) patients. Since 2012, total portal log-in frequency increased approximately 110% among patients who used the mobile application compared with 25% among those who did not use the mobile application ( P < .001).

CONCLUSION

Mobile access to electronic health portals has increased patient portal use, particularly among traditionally underserved populations. How this widely and immediately available technology affects patient expectations and experiences warrants additional study.
Inhibition of human cytomegalovirus major capsid protein expression and replication by ribonuclease P–associated external guide sequences
Authors: Deng Qiudi , Liu Yujun , Li Xin , Yan Bin , Sun Xu , Tang Wei , Trang Phong , Yang Zhu , Gong Hao , Wang Yu , Lu Jie , Chen Jun , Xia Chuan , Xing Xiwen , Lu Sangwei , Liu Fenyong
Published: February 2019

External guide sequences (EGSs) signify the short RNAs that induce ribonuclease P (RNase P), an enzyme responsible for processing the 5′ termini of tRNA, to specifically cleave a target mRNA by forming a precursor tRNA-like complex. Hence, the EGS technology may serve as a potential strategy for gene-targeting therapy. Our previous studies have revealed that engineered EGS variants induced RNase P to efficiently hydrolyze target mRNAs. In the present research, an EGS variant was designed to be complementary to the mRNA coding for human cytomegalovirus (HCMV) major capsid protein (MCP), which is vital to form the viral capsid. In vitro, the EGS variant was about 80-fold more efficient in inducing human RNase P-mediated cleavage of the target mRNA than a natural tRNA-derived EGS. Moreover, the expressed variant and natural tRNA-originated EGSs led to a decrease of MCP expression by 98% and 73%–74% and a decrease of viral growth by about 10,000- and 200-fold in cells infected with HCMV, respectively. These results reveal direct evidence that the engineered EGS variant has higher efficiency in blocking the expression of HCMV genes and viral growth than the natural tRNA-originated EGS. Therefore, our findings imply that the EGS variant can be a potent candidate agent for the treatment of infections caused by HCMV.
The Mega2R package: R tools for accessing and processing genetic data in common formats
Authors: Baron Robert V. , Stickel Justin R. , Weeks Daniel E.
Published: February 2019

The standalone C++ Mega2 program has been facilitating data-reformatting for linkage and association analysis programs since 2000. Support for more analysis programs has been added over time. Currently, Mega2 converts data from several different genetic data formats (including PLINK, VCF, BCF, and IMPUTE2) into the specific data requirements for over 40 commonly-used linkage and association analysis programs (including Mendel, Merlin, Morgan, SHAPEIT, ROADTRIPS, MaCH/minimac3). Recently, Mega2 has been enhanced to use a SQLite database as an intermediate data representation. Additionally, Mega2 now stores bialleleic genotype data in a highly compressed form, like that of the GenABEL R package and the PLINK binary format. Our new Mega2R package now makes it easy to load Mega2 SQLite databases directly into R as data frames. In addition, Mega2R is memory efficient, keeping its genotype data in a compressed format, portions of which are only expanded when needed. Mega2R has functions that ease the process of applying gene-based tests by looping over genes, efficiently pulling out genotypes for variants within the desired boundaries. We have also created several more functions that illustrate how to use the data frames: these permit one to run the pedgene package to carry out gene-based association tests on family data, to run the SKAT package to carry out gene-based association tests, to output the Mega2R data as a VCF file and related files (for phenotype and family data), and to convert the data frames into GenABEL format. The Mega2R package enhances GenABEL since it supports additional input data formats (such as PLINK, VCF, and IMPUTE2) not currently supported by GenABEL. The Mega2 program and the Mega2R R package are both open source and are freely available, along with extensive documentation, fromhttps://watson.hgen.pitt.edu/registerfor Mega2 andhttps://CRAN.R-project.org/package=Mega2Rfor Mega2R.
The effects of testosterone replacement therapy on the prostate: a clinical perspective
Authors: Miah Saiful , Tharakan Tharu , Gallagher Kylie A , Shah Taimur T , Winkler Mathias , Jayasena Channa N , Ahmed Hashim U , Minhas Suks
Published: February 2019

Male hypogonadism is a clinical syndrome characterized by low testosterone and symptoms of androgen deficiency. Prostate cancer remains a significant health burden and cause of male mortality worldwide. The use of testosterone replacement therapy drugs is rising year-on-year for the treatment of androgen deficiency and has reached global proportions. As clinicians, we must be well versed and provide appropriate counseling for men prior to the commencement of testosterone replacement therapy. This review summarizes the current clinical and basic science evidence in relation to this commonly encountered clinical scenario. There is gathering evidence that suggests, from an oncological perspective, that it is safe to commence testosterone replacement therapy for men who have a combination of biochemically confirmed androgen deficiency and who have either had definitive treatment of their prostate cancer or no previous history of this disease. However, patients must be made aware and cautioned that there is a distinct lack of level 1 evidence. Calls for such studies have been made throughout the urological and andrological community to provide a definitive answer. For those with a diagnosis of prostate cancer that remains untreated, there is a sparsity of evidence and therefore clinicians are “pushing the limits” of safety when considering the commencement of testosterone replacement therapy.
Recent advances in understanding biliary atresia
Authors: Wehrman Andrew , Waisbourd-Zinman Orith , Wells Rebecca G
Published: February 2019

Biliary atresia (BA) is a neonatal liver disease characterized by progressive obstruction and fibrosis of the extrahepatic biliary tree as well as fibrosis and inflammation of the liver parenchyma. Recent studies found that infants who will go on to develop BA have elevated direct bilirubin levels in the first few days of life, suggesting that the disease starts in utero. The etiology and pathogenesis of BA, however, remain unknown. Here, we discuss recent studies examining potential pathogenetic mechanisms of BA, including genetic susceptibility, involvement of the immune system, and environmental insults such as viruses and toxins, although it is possible that there is not a single etiological agent but rather a large group of injurious insults that result in a final common pathway of extrahepatic bile duct obstruction and liver fibrosis. The management and diagnosis of BA have not advanced significantly in the past decade, but given recent advances in understanding the timing and potential pathogenesis of BA, we are hopeful that the next decade will bring early diagnostics and novel therapeutics.
Case Report: Sarcoidosis mimicking head and neck cancer progression
Authors: Pratas Edgar , Carvalho João , Domingues Isabel , Pinheiro Sara , Amaral Susana , Khouri Leila , Costa Miguel , Eufrásio José , Pires Isonda , Davies Michael , Garcia Rita , Teixeira Margarida
Published: February 2019

Several case reports have been published describing the coexistence of sarcoidosis and cancer. In the literature, simultaneous occurrence of head and neck cancer and sarcoidosis is rarely reported.

In this paper we present a case of a 42-year-old man with squamous cell carcinoma of the oral cavity, locally advanced, which after surgery and adjuvant radiotherapy developed local persistence and progression in the mediastinal lymph nodes. The patient was submitted to chemotherapy and after a complete response, new suspicious mediastinal and hilar lymph nodes appeared in the thoracic computed tomography (CT) scan and 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) scan. To enroll the patient in a clinical trial, the patient underwent mediastinoscopy with mediastinal lymph node dissection. The histopathological findings were consistent with sarcoidosis and no metastatic disease was found. Since the patient had no symptoms and the levels of serum angiotensin converting enzyme were normal, no further pharmacological intervention was done. After 4 years of follow up the patient remains without evidence of cancer.

This case shows that although imagological techniques (CT and FDG-PET scan) are extensively used to assess the tumor response, false-positive cases can occur. Whenever it is possible a biopsy of the suspected metastatic site should always be performed.
The mediating role of types of coping styles in the relations between temperamental traits and staff burnout among psychiatric nurses
Authors: Brudek Paweł , Steuden Stanisława , Ciuła Grzegorz
Published: February 2019

Cel pracy

Wśród predyktorów wypalenia zawodowego wskazuje się na cechy temperamentu. Jednocześnie badacze podkreślają, że znaczenie właściwości temperamentalnych dla wystąpienia syndromu wypalenia u personelu medycznego uzależnione jest od wielu zmiennych pośredniczących, w tym także od sposobów postępowania w sytuacji problemowej. Nadrzędnym celem prezentowych badań było więc zbadanie, czy style radzenia sobie ze stresem pośredniczą w związkach między cechami temperamentalnymi a poszczególnymi komponentami wypalenia zawodowego pielęgniarek psychiatrycznych.

Metoda

Przebadano 60 kobiet pracujących w sektorze psychiatrycznej opieki zdrowotnej. W projekcie badawczym zastosowano trzy metody psychologiczne takie, jak: (1) Formalna Charakterystyka Zachowania – Kwestionariusz Temperamentu Strelaua i Zawadzkiego (FCZ-KT); (2) Kwestionariusz Radzenia Sobie w Sytuacjach Stresowych Endlera i Parkera (CISS); (3) Kwestionariusz Wypalenia Zawodowego Maslach (MBI-HSS).

Wyniki

Przeprowadzone analizy pozwoliły na konfirmację pośredniczącej roli stylu zadaniowego i stylu emocjonalnego w związkach cech temperamentu (żwawości, perseweratywności, reaktywności emocjonalnej wrażliwości sensorycznej, aktywności) z wypaleniem zawodowym. W przypadku stylu unikowego nie ma podstaw do uznania go za mediatora w obszarze analizowanych zależności.

Wnioski

W pomocy świadczonej pielęgniarkom psychiatrycznym: (1) w większym stopniu należy koncentrować się na wzmacnianiu zadaniowego, aniżeli na uświadamianiu szkodliwości unikowych tendencji w obszarze radzenia sobie; (2) ważne wydaje się kształtowanie umiejętności kreatywnego przeżywania emocji negatywnych ujawniających się w kontakcie z pacjentem.
Practice-Based risk assessment − a practical guide for oral healthcare teams: tooth wear
Authors: O'Toole Saoirse , Mylonas Petros , Bartlett David
Published: February 2019

Abstract: This paper discusses the presence of, and interplay between, erosion, abrasion and attrition as risk factors of tooth wear progression. The Basic Erosive Wear Examination is recommended as a simple practice-based screening tool to integrate into a risk assessment. Finally, the risk indicators are summarized and categorized using a high, medium or low risk classification system to facilitate practical risk assessment.

CPD/Clinical Relevance: This paper provides a practical guide for oral health providers to screen and risk assess tooth wear.
GESTÃO ESTRATÉGICA NA CAFEICULTURA: O CASO DO GRUPO PORTEIRA
Authors: Marcomini Gilson Rogério
Published: February 2019

O Brasil é o maior produtor e exportador mundial de café e é o segundo maior consumidor mundial de café. A qualidade é um fator determinante do preço e fator imprescindível para a aceitação do café no comércio internacional, especialmente, num setor caracterizado por alta competitividade. Neste sentido, o processo decisório e a adoção de práticas sustentáveis de produção têm apresentado impacto significativo no alcance dos objetivos empresariais de empresas rurais. Este artigo tem como objetivo identificar as práticas estratégicas adotadas em uma empresa que produz cafés especiais, a partir das quais, seus resultados têm sido diferenciados em relação à outras empresas tradicionais. Trata-se de um estudo qualitativo, cujos dados foram coletados por meio de entrevistas. Resultados demonstraram que os resultados financeiros obtidos foram melhorados em função da adoção de práticas estratégicas diferenciadas, com maior foco na qualidade do produto, como também na adoção de práticas sustentáveis.
ENGAJAMENTO DO CLIENTE: UMA REVISÃO SISTEMÁTICA COMPARANDO ENGAJAMENTO TRADICIONAL E ONLINE
Authors: Cristo-Andrade Silveli , Alves Helena
Published: February 2019

Baseado na necessidade que as empresas têm de se manterem competitivas e dinâmicas em um cenário cada vez mais virtual, esta revisão sistemática da literatura com análise bibliométrica sobre engajamento do cliente não online e online procura evidenciar a evolução do fenômeno do engajamento do cliente na literatura científica. Este estudo abarca 295 artigos publicados nos últimos 20 anos (1999-2018), na Web of Knowledge Social Sciences Citation Index (SSCI). Para alcançar esse objetivo, este fenômeno foi dividido em dois: um refere-se ao engajamento tradicional denominado aqui de engajamento não online. O outro trata-se do fenômeno ocorrendo virtualmente, mais especificamente via internet, considerado aqui como engajamento do cliente online. Para ambos os temas foram realizadas análises bibliométricas comparando seus resultados, demonstrando a multidimensionalidade que o tema exige.
Critérios de Escolha Utilizados pelos Clientes no Momento da Aquisição de Serviços de Planos de Saúde
Authors: Christo Pereira Neidy Aparecida , Pereira Uliana Mariana Marçal , Da Silva Angelo Rodrigues , Lemk Eva Wilma Soares , Biancardi Junior Hudson
Published: February 2019

Objetivou-se com este estudo verificar quais são os principais critérios de escolha utilizados pelos clientes no momento da aquisição de serviços de planos de saúde. Para tanto, buscou-se identificar a percepção dos usuários de planos de saúde quanto a fatores que influenciam na decisão de compra do plano e quais critérios eles levam em consideração ao adquirir este serviço. Foi realizada uma pesquisa descritiva e quantitativa, de uma amostra não probabilística com 349 usuários de planos de saúde. Os resultados foram obtidos por meio de análise de variância (ANOVA) e indicaram um índice de concordância quanto a importância dos critérios de escolha pesquisados, exceto a variável preço, que de todas, foi a única que não obteve resultado significante no teste estatístico aplicado. Percebe-se pelo presente estudo que a variável preço, quando avaliada juntamente com outros critérios de escolha, não é considerada significativa no momento da compra de serviços de planos de saúde.
Estratégias de Responsabilidade Social Corporativa e a Confiança Percebida
Authors: De Sousa Walter Souto
Published: February 2019

Objetivou-se identificar as dimensões da Responsabilidade Social Corporativa que estão associadas à confiança dos stakeholders em empresas socialmente responsáveis. Foram identificadas quatro dimensões da RSC e uma da confiança, que são mensuradas por meio de variáveis sob a forma de afirmações, sendo a base para o questionário desta investigação. Foi realizada uma pesquisa descritiva, quantitativa, com dados primários e corte transversal. Com o questionário aplicado, foram identificados 210 respondentes que afirmaram conhecer alguma empresa com ações voltadas a RSC. Os resultados apontaram para uma concordância perante a percepção de valorização das ações de RSC e uma concordância menos expressiva quanto à percepção de confiança. Também foi identificada uma relação direta das Dimensões Social e Governo, e inversa da Dimensão Cliente com a variabilidade da percepção de confiança dos stakeholders em empresas socialmente responsáveis, atribuindo assim à identificação da existência de uma interferência da RSC na percepção de confiança.
Viabilidade de uma Startup baseada em Economia Colaborativa
Authors: Longen João Victor de Pauli , Pereira Guilherme Henrique , Ryba Andréa , Da Silva Jr. Roberto Gregorio
Published: February 2019

As constantes mudanças pelas quais o mundo dos negócios vem passando, aumentam os riscos para os novos empreendimentos, mas também apresentam oportunidades para negócios inovadores, como as startups baseadas na economia colaborativa. Na análise de viabilidade econômica desses novos negócios um dos desafios é a projeção do fluxo de caixa sem dispor do histórico de desempenho. Assim, foi realizado um estudo de caso em empresa nascente que, via web, promove a locação de equipamentos pesados da construção civil. O estudo compreendeu três etapas: detalhamento do caso, avaliação do mercado e análise da viabilidade do negócio. Os resultados obtidos indicaram que o negócio proposto tem boa receptividade e potencial no mercado. Além disso, seu crescimento pode ser estimado com base em um modelo polinomial ajustado, possibilitando a análise de sua viabilidade econômica por métodos convencionais, o que demonstrou a sua dependência de um crescimento expressivo das receitas nos dois anos iniciais.
The effect of low dose acetylsalicylic acid on platelet aggregation in patients with coronary heart disease at rest and during physical exercise testing
Authors: Roebiono Poppy S , Kusmana Dede , Sani Aulia , Baraas Faisal , Yusuf Andang , Sedyawan Jetty , Rilantono Lily I
Published: February 2019

[no abstract available]
Inhibition of spermatogenesis by progesterone and androgen combinations in C3H mice

Authors: Wuyung Puspita Eka , Soeradi Oentoeng , Pringgoutomo Sudarto
Published: February 2019

Inhibition of Spermatogenesis by Progesterone and Androgen Combinations in C3H Mice
Development of Elisa for rapidÂ detection of anti-dengue antibody
Authors: Soebandrio Amin
Published: February 2019

[no abstract available]
Fluconazole administration during irradiation of head and neckÂ cancer
Authors: Susworo R. , Sjarifuddin Pudji K. , Gondhowiardjo Suhartati , Juniarti Juniarti
Published: February 2019

[no abstract available]
Methods of susceptibility testing in Indonesia
Authors: Josodiwondo Suharno
Published: February 2019

[no abstract available]
Recent diagnostic methods of malaria and filariasis in the Department of Parasitology, Faculty of Medicine University of Indonesia, Jakarta, Indonesia
Authors: Hadidjaja Pinardi
Published: February 2019

[no abstract available]
Atracurium infusion assessment
Authors: Sunatrio S.
Published: February 2019

[no abstract available]
Decreased basal and n-Butyrate stimulated colonic water and electrolyte transport in the pre- and postnatal malnourished rat
Authors: Firmansyah Agus
Published: February 2019

[no abstract available]
Why New Drugs, Treatments, and Medical Devices Still Needs to be Tested Clinically Before Making it Available in the Market? A Systematic Review
Authors: Patel Naiya
Published: February 2019

Objective
Testing a new drug, treatment, and medical device clinically is critically important before prescribing it to patient. Not determining the drug’s safety and efficacy through clinical trials might impose life threatening outcomes on its consumers. The research paper describes the critical factors associated for testing any new drugs clinically, as limited research is performed in this field of public health.

Study Design
A qualitative systematic literature review was performed by mining relevant original peer reviewed research papers as well as some online resources like MedlinePlus due to limited availability of studies on such critical topic.

Methods
The databases used were Web of Sciences core collection, PubMed, Google scholar. The keywords used to search research papers were “clinical trials”, “testing new drugs”, “history of testing drugs”, “evidence-based medicine”.

Conclusion
Drugs which are prescribed to critical target population like pregnant women and children should be more often clinically tested if possible as majority of them are available in the market without Food and Drug Administration (FDA) approval. The abusive potential of any new drug could end up taking lives of innocent individuals. More evidence-based medicine can help translate research results on a heterogeneous population efficiently.
Aldosterone- and cortisol-co-secreting adrenal tumors: an uneasy sum of well-known parts (review)
Authors: Shifman Boris M. , Platonova Nadezhda M. , Molashenko Natalya V. , Troshina Ekaterina A. , Romanova Natalia Yu. , Kolesnikova Galina S.
Published: February 2019

Primary aldosteronism (PA) is the most common form of secondary arterial hypertension. In patients with PA, more so than in the general population, there is a prevalence of insulin resistance, diabetes mellitus, metabolic syndrome, osteoporosis, and symptoms of depression; these conditions are more likely to manifest a gluco- rather than mineralocorticoid excess. This fact is of particular importance in light of recent studies that have shown that PA is often associated with glucocorticoid excess. Since the first reports of cases of combined secretion of aldosterone and cortisol in 1979, the number of cases of so-called Connshing syndrome has increased. An analysis of data from recent studies suggests that hypercortisolism in PA is closely associated with an increased risk of cardiovascular complications, metabolic disorders and post-surgical adrenal insufficiency. The most important diagnostic problem in adenomas with combined secretion is the risk of false interpretation of the results of adrenal venous sampling (AVS). The indications that suggest aldosterone-and-cortisol-co-producing adenoma are the lack of suppression of cortisol levels following a night test with 1mg of dexamethasone, and an adrenal tumo of over 2.5cm. As an alternative test capable of differentiating this type of tumor, a number of researchers have proposed measuring the level of so-called hybrid steroids in the peripheral plasma and urine. Taking into account the high prevalence and potential risks, ruling out of excess corisol secretion is obligatory in all cases of PA before AVS and when planning surgery.
LAS LEGUMINOSAS CESALPINIOIDEAS DE LA PROVINCIA DE SANTA FE
Authors: LUCHETTI A. M. , EXNER E.
Published: February 2019

Como contribución al estudio de la fl ora de Santa Fe, se presenta la revisión sinóptica de las Leguminosas Cesalpinioideas que crecen espontáneamente en el territorio de esta provincia. En total se incluyen 19 especies distribuidas en 9 géneros. Los siguientes taxones: Senna aphylla (Cav.) H.S. Irwin & Barneby y Senna spectabilis (DC.) H. S. Irwin & Barneby, son excluidos de esta fl ora. Para cada género se proporcionan claves que permiten el reconocimiento de sus especies. Para cada taxón se incluye su nombre correcto aceptado por la comunidad botánica y, cuando corresponde, su basónimo; nombres vernáculos, ejemplares de referencia, hábito, iconografía, distribución geográfi ca y observaciones fenológicas y ecológicas.
EFECTO DE TIPO DE TUTORES Y DENSIDAD DE SIEMBRA SOBRE EL RENDIMIENTO DE ÑAME ESPINO
Authors: LUNA CASTELLANOS L. L. , TAMARA MORELOS R. E. , GARCIA PEÑA J. A.
Published: February 2019

El objetivo de la presente investigación fue determinar el efecto de tres tipos de tutores (tutor individual, espaldera simple y espaldera doble) y dos densidades de siembra (14,285 y 20,000 plantas/ha) sobre el rendimiento de Dioscorea rotundata cv brasilero. El experimento se realizó bajo un diseño de bloques completos al azar con arreglo en parcelas divididas con cuatro repeticiones. Las variables evaluadas fueron: rendimiento total de tubérculos (t. ha -1), rendimiento de tubérculos comerciales, y adicionalmente se realizó un análisis económico de los tratamientos. Los resultados obtenidos mostraron diferencias altamente significativas para el factor densidad de siembra. Al emplear la densidad de 20,000 plantas/ha se obtuvieron los mayores  rendimientos totales (26,73t. ha -1 ) generando incrementos en 9,64% respecto a la menor densidad (14,285 plantas/ha) para esta variable. La utilización combinada de espaldera simple y la densidad de 20,000 plantas/ha generó aumentos de 9,3% en rendimiento de los tubérculos.
Job Satisfaction among the Library and Information Professionals in Fiji A Survey
Authors: Sohail Md
Published: February 2019

The paper deals with the job satisfaction of the library and information professionals working in government and the private sector libraries in the Fiji. The study was carried out in relation to what is the happiness level of working with their co-workers and how much they are satisfied with their wages and job securities. Library professionals have experienced ignoble and asymmetrical salary payments, lacks of proper housing, inadequate facilities in libraries, low social status given to them and limited opportunities for professional development in Fiji. The main purpose of this study is to find out the major factors affecting career choices, level of job satisfaction, and perceptions of the general image of library professionals in Fiji. This article explores, how much satisfaction of these library professionals, derive from their chosen career and examine the degree of dissatisfaction or areas of discontent among then. Results show that the female professionals are more satisfied from their job as compared to males. Library professionals who are much experienced are possess a proportionately high level of job satisfaction as compared to other age groups. Whereas, those professionals are between ages of 28-35, having a comparatively ignoble level of job satisfaction, compared to another age group of professionals. Unmarried professionals possess a comparatively ignoble level of job satisfaction as compared to married or widow and separated hold comparatively high job satisfaction.
Mapping of Crowdsourcing Research A Bibliometric Analysis
Authors: Malik Basharat Ahmad , Aftab Azra , P.M. Naushad Ali
Published: February 2019

This study presented a bibliometric examination of the crowdsourcing publications. The objective of this study is to bibliometrically examine the publications related to crowdsourcing in the Science Citation Index Expanded of the Web of Science. A systematic search has been carried out for publications between 2008 and 2017. The parameters analysed included document type, language, most prolific journal, leading countries/territories, institutions and authors in terms of total publications, independent publications, collaborative publications, first authors, corresponding authors and single authors. Highly cited articles and the future direction of hot topics are also investigated. 81 per cent of the total publications are articles. English remains the dominant language and accounted for nearly 100 per cent of the total output. The USA, China and the UK produced 80 per cent of total production. PLOS One was leading journal in terms of total output and total citation till 2016. It was found that 1459 articles, including 1347 first authors, 1443 corresponding authors and 79 single authors, were published by 6973 authors. Fritz Steffen and See Linda were the most prolific authors. This paper will be useful for researchers to know the current trends and achievements of crowd - sourcing research.
Foreign Authorship Pattern in Selected Library and Information Science Journals of India
Authors: Mondal Dhiman , Maity Arabinda
Published: February 2019

Foreign authorship pattern to three leading Indian library and information science (LIS) journals during 2008 to 2017 has been examined to identify the acceptability and popularity of Indian LIS journals among foreign authors. The present study investigates the authorship pattern in terms of different aspects like journals, years, collaborations, prolific authors, countries, research areas, cited papers and citations. It is found that in last 10 year the three LIS journals publish total 186 foreign authored article having total 1267 citation and two-authored papers are predominant. Besides, the authors from Nigeria share maximum articles followed by USA. It is recommended that the Indian LIS authors need to emphasis more on international collaboration to output more foreign authored contributions in national level journals to enrich journals literature.
Personality Antecedents of Internet Overuse Behaviour Among College Students
Authors: Thiyagarajan Yuvaraj , Armugam Suresh
Published: February 2019

Internet has become a ubiquitous feature at home, school and the workplace, as the worldwide population of Internet users has grown rapidly in the recent years. However, its excessive use, especially using it unnecessarily, is found to affect psychological functioning of the users, more particular harm caused among the youngsters. Researchers have found some of the individual factors, particularly the individual personality, that significantly correlate with the both the trend in usage of Internet and its overuse as well. Hence, investigators of this study wanted to examine whether personality is predicting internet overuse behaviour among college going students. For this a sample of 153 college and university students (92 male and 61 female) in the age range of 18 to 25 years were selected non-randomly from 4 different institutions in Tamil Nadu. They were administered with the 120 item IPIP NEO personality inventory and 36 item online cognition scale. Regression analyses were carried out test the hypotheses, using SPSS (version 23.0). Results showed that the personality factors, except openness to experience were found to be predicting internet overuse, with an overall R2 value of 0.37. Among the factors, excitement seeking of extraversion, anxiety, anger and depression facets of neuroticism and self-efficacy, orderliness, cautiousness and dutifulness facets of conscientiousness were significantly contributing. To infer, the respondents in the sample, who were highly sensation seekers, anxious and depressive by nature, low on self-efficacy, not being orderly and dutiful tend to overuse internet. Among the personality factors, conscientiousness was a strong predictor of internet overuse in the sample
Effectiveness of Subliminal Stimuli in Lie Detection: Use of Physical Countermeasures
Authors: Sharma Mandeep , Yadava Amrita , Sharma Nov Rattan
Published: February 2019

The objective of the present investigation was to study the effectiveness of subliminal stimuli in reducing the probability of use of countermeasures during polygraph was considered. Further, use of countermeasures (physical) would be more for supraliminal stimuli as compared to subliminal stimuli. Purposive total samples of 79 adults with (age range between 20-28 years) were selected for the present study. Windows Based Computerised Lie Detector (CLD-118) and Aversion Therapy Instrument (MBT-498) were used in present study. For analyses of the data, Friedman Test (non-parametric) followed by Wilcoxon Signed-Rank Test (non-parametric), were applied. In the present investigation the effectiveness of subliminal stimuli in deterring the execution of countermeasures was studied, revealed that subliminal stimuli acted as a deterrent to physical countermeasures. The present findings indicate that subliminal stimuli can be used as a deterrent to countermeasures (Physical) in Lie Detection.
Image Automatic Categorisation using Selected Features Attained from Integrated Non-Subsampled Contourlet with Multiphase Level Sets
Authors: Uppada Rajyalakshmi , Sanagapallela Koteswara Rao , Kodati Satya Prasad
Published: February 2019

A framework of automatic detection and categorization of Breast Cancer (BC) biopsy images utilizing significant interpretable features is initially considered in discussed work. Appropriate efficient techniques are engaged in layout steps of the discussed framework. Different steps include 1.To emphasize the edge particulars of tissue structure; the distinguished Non-Subsampled Contourlet (NSC) transform is implemented. 2. For the demarcation of cells from background, k-means, Adaptive Size Marker Controlled Watershed, two proposed integrated methodologies were discussed. Proposed Method-II, an integrated approach of NSC and Multiphase Level Sets is preferred to other segmentation practices as it proves better performance 3. In feature extraction phase, extracted 13 shape morphology, 33 textural (includes 6 histogram, 22 Haralick’s, 3 Tamura’s, 2 Graylevel Run-Length Matrix,) and 2 intensity features from partitioned tissue images for 96 trained images
Biofuels for Defence Use: Past, Present And Future
Authors: Grover Atul , Meher Lekha Charan , Singh Ranjit , Singh Abhinav , Tiwari Sudhanshu , Dwivedi Sanjai Kumar , Bala Madhu
Published: February 2019

Defence sector desires to attain energy self-sufficiency and security. In recent years, emergence of biofuel as an alternative source has raised the hopes of Defence. Ethanol and bio-diesel are currently being used as blends in different parts of the world. While, bio-diesel is mostly being blended in 2-20% in different parts of the world, ethanol blending has reached upto 85%. Owing to the sustainability reasons, the choice of feedstock for ethanol production is gradually changing from corn to lignocelluloses biomass. Jatropha curcas, is still the choice feedstockfor bio-diesel in most third world countries. This institute has put in rigrous efforts to identify high yielding varieties of Jatropha, improving its yield, standardizing trans-esterification to obtain high quality bio-diesel and its trials and testing in various vehicles and equipment. Second generation biofuels using biomass such as farm and forest wastes as feedstocks are promising in terms of their overall sustainability and volume produced. They can be used as drop in fuels. However, time is required to utilize their potential fully. Algae, the third generation biofuel feedstock still needs extensive R&D to make it economically sustainable. Whatever, the technology used, defence forces will accept any biofuel, which should be available constantly and priced below the existing petroleum fuels. The scope of producing by-products and finding a lucarative market for these products can ensure that prices ofbiofuels remain lower than the petroleum fuels