bluuebunny/crossref_metadata_2025 huggingface dataset:
Clinical Characteristics, Serological and Radiological changes of Patients With COVID-19 
Authors: Yang Zhiwei , Yu Mingxue , Li Ganwen , Liu Guirong , Xie Jinjun , Song Hongzhong , Li Gang , Jie Yusheng
Published: May 2020

Background Since December 2019, an outbreak of coronavirus disease 2019 (COVID-19) that began in Wuhan and rapidly spread globally. The speed and scope of spread of COVID-19 makes urgent of the defining clinical characteristics, serological and radiological changes of the affected patients.Method 7 patients with laboratory-confirmed COVID-19 who admitted to the Third affiliated hospital of Sun Yat-sen university Yuedong hospital from January 2020 to March 2020 were retrospectively enrolled and their clinical features, serological and radiological longitudinal changes were analyzed.Results Among the 7 patients, all (100%) had a clear epidemiological history. The most common symptoms were respiratory symptoms 6 (85.7%), and only 2 (28.6%) of the patients had fever at their first visit. The cohort included 4 (57.1%) common types and 3 (42.9%) severe types. Two (28.6%) common types patients developed to severe type in a short time. All of the 7 patients (100%) had abnormal liver function, normal renal function and normal procalcitonin. The detection time of specific antibody in 7 patients was 5~13d after symptoms. Before the specific antibody could be detected, the absolute value of lymphocytes decreased in 2 (28.6%) common type cases transferred to severe type cases accompanied with obvious progress in pulmonary imaging, and the phenomenon of decreased albumin and elevated globulin occurred in 6 patients (85.7%). The predominant pattern of lung lesions observed was bilateral (71.4%) and mainly near the pleura at the first diagnosis. Bilateral pulmonary involvement occurred in 6 cases (85.7%) during the course of disease. In 4 cases (57.1%) with obvious pulmonary lesions, the absolute value of lymphocytes decreased, albumin decreased and globulin increased during the course of the disease. Conclusion Serum specific antibodies can be detected within 2 weeks of onset. Close observation of the dynamic changes of absolute value of blood lymphocytes, serum albumin and globulin which were related to pulmonary imaging changes in patients will contribute to assessment of COVID-19.
Trend Analysis Modelling and Prediction of Epidemic COVID-19 for US, Italy, Spain and Pakistan
Authors: Bashir Muzaffar , Sattar Habeeba Abdul , Zaheer Aliya
Published: May 2020

The evidence of Covid19 outbreak was first received in December 2019 in China and it spread out rapidly on the map of the world. The cases of Coronavirus are increasing day by day around the world due to which mortality rate raises hastily. In the matter of days, WHO declared Covid19 as pandemic of the decade. So far, it is controlled by taking strict precautions in terms of lockdown and supervised treatments at the hospital. As its epidemic is severely breaking the scale, there is a necessity to recognize and evaluate its extension in people on each new day. We collected time series data from January 22, to April 28, 2020 which includes the number of confirmed patients (CP) and reported deaths (RD) of 186 countries all around the world. We choose to evaluate the data for US, Italy, Spain and Pakistan. We are selecting here the data up to April 28, 2020, however the data is automatically updated from Humanitarian Data Exchange on daily basis for all the countries suffering from this pandemic. In this study, three parameters logistic (autocatalytic) model is applied to characterize the disease which determine the size of epidemic with the most populated hit cases around the world respectively and predict the life cycle of COVID 19 cases by using Gaussian based prediction model. It is determined that there are worst numbers of cases of Coronavirus that are found in US and the number of CPs and RDs grow exponentially around the world underneath Spain, Italy, UK and France etc. The epicentre of this pandemic was the city of Wuhan, China. The firm defence that has been taken is to quarantine the people and the patients were cured in organized hospitals.
Impact of Angiotensin-converting Enzyme Inhibitors and Angiotensin Receptor Blockers on Inflammatory Responses and Viral Clearance in COVID-19 Patients: A Multicenter Retrospective Cohort Study
Authors: HUANG Linna , CHEN Ziying , NI Lan , CHEN Lei , ZHOU Changzhi , GAO Chang , WU Xiaojing , HUA Lin , CUI Xiaoyang , TIAN Ye , ZHAN Qingyuan
Published: May 2020

Objectives: To evaluate the impact of angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin receptor blockers (ARBs) on coronavirus disease 2019 (COVID-19) patients.Methods: We included 229 patients with confirmed COVID-19 in a multicenter, retrospective cohort study. Propensity score matching at a ratio of 1:4 was introduced to eliminate the potential confounders. Patients were assigned to the ACEI/ARB group (n=40) or control group (n=160) according to whether they were current users of medication. Results: Compared to the control group, patients in the ACEI/ARB group had lower levels of plasma IL-1β [(6.27±0.50) vs. (8.23±0.39) pg/ml, P=0.028], IL-8 [(35.74±4.00) vs. (45.88±2.06) pg/ml, P=0.037] and TNF-α [(8.79±0.40) vs. (10.91±0.21) pg/ml, P<0.01]. Patients with the current use of ACEIs/ARBs had a higher risk of shock (23% vs. 8%, P<0.01). Decreased lymphocyte counts [(0.85±0.45) vs. (1.02±0.52)*10^9/L, P=0.041] and elevated plasma levels of IL-10 [(7.39±0.51) vs. (6.18±0.16) pg/ml, P<0.01] were also important discoveries in the ACEI/ARB group. Patients in the ACEI/ARB group had a prolonged duration of viral shedding [(25±7) vs. (20±6) days, P=0.031] and increased length of hospitalization [(23±12) vs. (16±8) days, P<0.01]. These trends were similar in patients with hypertension.Conclusions: For patients with excessive inflammatory responses and stable hemodynamics, ACEIs or ARBs might be tried to relieve the inflammatory storm, but the antiviral treatment should be enforced and the hemodynamics should be monitored closely; for patients with low levels of proinflammatory factors or instability hemodynamics, the agents might not be used to avoid a delay in viral clearance or increase the risk of shock.
A AUSÊNCIA DE UMA EFETIVA POLÍTICA CARCERÁRIA COMO CONSEQUÊNCIA DO NÃO ATENDIMENTO DO PRIMADO DA DIGNIDADE DA PESSOA HUMANA DAS PESSOAS PRESAS
Authors: MARTINS Monah
Published: May 2020

A presente pesquisa procurou analisar a eficiência do sistema carcerário, no que diz respeito ao primado da dignidade humana. Analisando-se a etapa de execução penal, enquanto momento sucessivo da sentença penal condenatória, a discussão sobre o tema se mostra relevante, uma vez que, afirmada a violação a essa dignidade, será preciso questionar a necessidade de estabelecimento de novas formas de punição, desapegado de um aspecto meramente punitivo. O trabalho não tem por finalidade esgotar ou elucidar as temáticas aqui envolvidas, mas mostrar a relevância, na medida em que contribui com o debate em torno do tema.
O CONSERVADORISMO PRESENTE NA LEGISLAÇÃO BRASILEIRA E A MANEIRA QUE É REFLETIDO NO ABORTO
Authors: LEONI Luiza Taveira
Published: May 2020

A presente pesquisa científica se insere na área de Direito Civil e também Criminal, com o intuito de destacar os conceitos de pessoa e sua dignidade, e como a legislação se desenvolve em relação a interrupção voluntária da gravidez, mais especificamente como os direitos da gestante são abordados, como determinadas posicionamentos jurisprudenciais possuem argumentos favoráveis para a mulher grávida, visto que a atual Constituição Federal Brasileira garante o direito à vida e também a dignidade humana. No entanto, quando se trata de analisar a situação da maneira que ela realmente ocorre, acaba sendo um pouco diferente, principalmente quando se trata da realidade de mulheres com situações econômicas menos favorecidas. Neste caso, vários obstáculos são encontrados, pois não possuem condições financeiras para que façam o procedimento do aborto de forma segura, o que as leva a recorrer a clínicas despreparadas, ocasionando, na maioria das vezes, lesões graves na gestante, ou até mesmo a sua morte. Esse estudo foi feito através de pesquisas históricas, e da leitura de doutrinas atuais de Direito Civil. Tal pesquisa foi realizada pelo intermédio de doutrinas, livros, revistas, textos normativos e artigos científicos, conduzindo a um conhecimento antes inexistente sobre o assunto.. Como resultados desta pesquisa nota-se que é de extrema importância o conhecimento aprofundado sobre a definição e conceito de pessoa, a necessidade de conhecer o principio da dignidade humana, e como a legislação e o posicionamento jurisprudencial aborda e define o aborto.
ANÁLISE SOBRE A EFICÁCIA E APLICABILIDADE DA COLABORAÇÃO PREMIADA
Authors: VILLARROEL Teresa Cristina De Lima , VOLPE FILHO Clóvis Alberto
Published: May 2020

O presente artigo realiza uma análise a respeito da Colaboração premiada de maneira bastante ampla, tendo início por meio do direito comparado entre o sistema brasileiro e institutos correlatos de outros países, em diferentes períodos. Posteriormente foi realizado um estudo das legislaçẽos  do Brasil  que possuem espécies de colaboração. Tendo esse material reunido, foi possível realizar um estudo mais detalhado a respeito da Lei nº 12.850/13, Lei de combate às organizações criminosas, no que se refere às inovações relativas à colaboração premiada.
The economic mechanism for the formation of land rent at agricultural enterprises
Authors: Shyian Dmytro , Moskalenko Anatolii , Kirichenko Kseniia
Published: May 2020

The current stage of land relations in the agrarian sector is characterized by significant development of lease relations. Today, these relationships are heavily influenced by competition for land tenure, leading to increased land payments. Considering this, as well as the prospects for the agricultural land market formation, the task was to assess the dependence of agricultural land rent on the intensity and economic efficiency of wheat, corn for grain, sunflower production. The research was carried out on the example of agricultural enterprises of Kharkiv region. Grouping, a graphical method was chosen as research methods. The subject of the study was also the rent dynamics for agricultural land in Kharkiv region and Iowa, the USA. The obtained results made it possible to establish the fact that the rent value depends on the total amount of expenses, and the expenses on the articles «wages», «depreciation». It is concluded that the reasons for this may be related to the investment of these enterprises in human capital and the fixed assets that make them lease on more favorable terms for share owners. No dependence was found between the rent value on the value of the yield and the financial result on the selected crops. At the same time, there is a clear tendency that with the increase in the value of the rent, there is an increase in the ratio of its value to the value of costs and income from the crop sector. It is concluded that this can lead to a decrease in investment opportunities for the enterprises with the highest level of lease payments for agricultural land.
En busca de protección a las puertas de Europa: refugiados, etiquetado y prácticas disuasorias en la frontera sur española
Authors: López-Sala Ana , Moreno-Amador Gracia
Published: May 2020

A partir de un análisis que subraya las prácticas de contención del acceso de los refugiados desde el denominado paradigma disuasorio, este artículo usa la literatura del etiquetaje para investigar la gestión del refugio en la frontera sur española a lo largo de las últimas tres décadas. Además de detenernos en algunos elementos del marco regulatorio del refugio en España y su evolución, el análisis presentado se basa en 34 entrevistas en profundidad semiestructuradas realizadas entre 2016 y 2019 en Madrid, Cádiz, Ceuta y Melilla a diferentes actores públicos y miembros de organizaciones sociales, nacionales e internacionales, implicados en la gestión del refugio en España. Las conclusiones del análisis indican que el etiquetado de la inmigración africana como una inmigración exclusivamente laboral ha moldeado la gestión política del refugio en la frontera sur española a través de prácticas que han impedido, limitado y disuadido el acceso de potenciales solicitantes de asilo al sistema español de protección internacional. Por ello la gestión del refugio ha quedado ampliamente supeditada al control migratorio.
Recent Advances in the Development of “Curcumin Inspired” Compounds as New Therapeutic Agents
Authors: Borosky Gabriela L. , Laali Kenneth K.
Published: May 2020

Despite a huge body of research in the past two decades investigating the antioxidant, antiinflammatory,
anti-microbial, and anti-carcinogenic properties of curcumin (CUR), a CUR-based antitumor
drug is yet to be developed. Lack of success in achieving this goal stems from CUR’s unfavorable
biophysicochemical features, particularly poor solubility, low bioavailability, and rapid metabolism,
coupled with a complex biological profile making it difficult to determine its mechanism of action.
A significant body of literature aimed at improving its physicochemical properties through synthesis
or by designing delivery methods has been published, and the progress in these areas has been
reviewed. The present review aims to summarize recent progress in the synthesis of structurally diverse
“curcumin-inspired” compounds along with computational docking and bioassay studies,
through which a number of promising analogs have been identified that warrant further study.
Hiccups: A Non-Systematic Review
Authors: Leung Alexander K.C. , Leung Amy A.M. , Wong Alex H.C. , Hon Kam L.
Published: May 2020

Background:

Hiccups are a universal phenomenon. They are usually benign and selflimited.
Persistent or intractable hiccups, although rare, can be debilitating and may indicate the
presence of an underlying pathological process.

Objective:

To familiarize physicians with the pathophysiology, etiology, evaluation, and management
of children with hiccups.

Methods:

A search was conducted on December 10, 2019, in Pubmed Clinical Queries using the
key terms "hiccup" OR “hiccough” OR “singultus”. The selected publication types included all
clinical trials (including open trials, non-randomized controlled trials, and randomized controlled
trials), observational studies, and reviews (including meta-analysis and narrative reviews) published
within the past 10 years. Only papers published in the English literature were included in this
review. The information retrieved from the above search was used in the compilation of the present
article.

Results:

Overdistension of the stomach is the most commonly identifiable cause of acute hiccups,
followed by gastroesophageal reflux and gastritis. Other causes of hiccups, notably persistent and
intractable hiccups, include an underlying gastrointestinal, neurological, cardiovascular, pulmonary,
infectious, and psychogenic disorder. Persistent or intractable hiccups can be a harbinger of
serious medical pathology. A detailed history and thorough physical examination may provide
clues for the etiology of the hiccups. The treatment of hiccups should be directed at the underlying
cause whenever possible. Bouts of acute hiccups less than 48 hours rarely require medical intervention
as they usually resolve within minutes. Treatment may be considered when hiccups are bothersome,
persistent, or intractable. Treatment modalities include lifestyle changes, physical maneuvers,
pharmacotherapy and, very rarely, surgical intervention.

Conclusion:

Acute hiccups are usually benign and self-limiting. Persistent or intractable hiccups
can be a harbinger of serious medical pathology. The underlying cause should be treated if possible.
There are no formal guidelines for the treatment of hiccups. Currently, most of the methods
proposed are based on case reports and anecdotal evidence. Terminating an episode of hiccups can
be very challenging for a clinician but may tremendously improve the patient’s quality of life. It is
hoped that future well-designed and better-powered studies will provide us with more information
on the efficacy of various treatment modalities for hiccups.
Medicine and Healing in the Pre-Socratic Thought - A Brief Analysis of Magic and Rationalism in Ancient Herbal Therapy
Authors: Santacroce Luigi , Topi Skender , Haxhirexha Kastriot , Hidri Shkelqim , Charitos Ioannis Alexandros , Bottalico Lucrezia
Published: May 2020

Background:

Medicine has gone through many schools of thought before arriving in the version we see in our world today. In the beginning, it was based on religion, superstition, and magic plants for therapy. This approach was practiced for many centuries until a period of cultural development arrived. This change occurred in the ancient Greek era, when new theories on nature arose: physiokratia emerged to describe the nature of humanity, including its genesis and supporting phenomena. From the various mystical traditions, we have come to understand the natural phenomena that surround the universe, thanks to the knowledge of the "hidden causes" that emerged due to this trend of philosophical thought.

Methods:

We studied ancient texts to determine the common roots between myth, therapy, and religion of medical cultures in the pre-Hippocratic era and the era of pre-Socratic philosophers.

Results:

This study is focused on the period of time before and during pre-Socratic thought, showing that there are many similarities in the approach of therapy for various diseases in that era. The Greek contribution to Western medicine was in the development of a rational system of thought that has been transmitted in medical culture. This attempt to interpret humanity was called philosophy. Hippocrates, who came after the pre-Socratics, changed the old approach to patients. When the approach to medical diagnosis and healing changed, it affected the therapy of other ancient cultures. The ancient Greeks were influenced by other civilizations’ approaches to therapy, especially with the use of plants and the different mythological and religious outlooks connected to this use. Despite the emergence of pre- Socratic rationalism, supernatural beliefs remained even when the use of herbs was no longer practiced in direct connection to their origins in myth and magic. The first detachment of magic therapy occurred later with the father of medicine, Hippocrates.

Conclusion:

The ancient Greeks invented the rationalist doctrine, which influenced medicine. Thus, the birth of philosophy, through its many stages, has influenced therapeutic patterns in medicine, especially with medicinal herbs.
A Patent Review on Nanotechnology-Based Nose-to-Brain Drug Delivery
Authors: Singh Ruchita , Brumlik Charles , Vaidya Mandar , Choudhury Abhishek
Published: May 2020

Background:

Current cerebral drug delivery to the brain and Cerebrospinal Fluid (CSF) is
limited by the Blood-Brain Barrier (BBB) or the blood-blood Cerebrospinal Fluid (CSF) barrier. The
popular, non-invasive, intranasal delivery provides an exciting route for topical and systemic applications.
For example, intranasal drug delivery of Central Nervous System (CNS) drugs can be designed
to pass the BBB barrier via the nose-to-brain pathways. Recent nanotechnology research and patenting
focus mainly on overcoming typical limitations including bioavailability, transport, BBB penetration,
targeted delivery, controlled release rate and controlled degradation.

Objective:

The aim of the present study was to assess the state-of-the-art of nose-to-brain drug delivery
systems and the role of nanotechnology in targeted delivery for the treatment of CNS and related therapeutic
conditions.

Methods:

Patent and related searches were made with analytics to explore and organize nanotech work
in intranasal drug delivery to the brain. Technical advancements were mapped by API, formulation and
performance criteria. Patents and published patent applications were searched with concept tables of
keywords, metadata (e.g., assignee) and patent classes (e.g., International Patent Classes and Cooperative
Patent Classes).

Results:

The reviewed patents and published applications show a focus on formulations and therapeutic
indications related to the nano-based nose-to-brain drug delivery. The main patented materials were
surface modifiers, delivery systems and excipients.

Conclusion:

Surface modified nanoparticles can greatly improve drug transport and bioavailability of
drugs, particularly higher molecular weight drugs. The most commonly used surface modifiers were
chitosan, lectin and cyclodextrin-cross-linker complex. Nanoformulations of herbal drugs could increase
drug bioavailability and reduce toxicity. Biotechnology-related drug delivery approaches such
as monoclonal antibodies and genetically engineered proteins (molecular Trojan horses) deliver large
molecule therapeutics.
Gonzalo Olivares Rey de Castro
Authors: Calatayud Rosado Luis , Ríos Vizcarra Gonzalo
Published: May 2020

Hablar de Gonzalo Olivares significa hablar del representante más importante de la modernidad arquitectónica de Arequipa. En su persona se encuentran las características del profesional comprometido, apasionado por los ideales modernos del siglo XX, a la vez que se erige como un arquitecto sensible al patrimonio cultural de su región.
Jorge Burga: Historia de la arquitectura peruana, tomo I. Arquitectura popular
Authors: Ramos Chuquimia Diana
Published: May 2020

Con esta reseña se nos da la oportunidad de hablar del patrimonio en su concepción más «humilde». Valorar y revalorar el conocimiento ancestral como la tradición constructiva, aún vigente, de los pueblos antiguos de nuestro país. La mezcla de los saberes simbólicos y su diversidad tipológica en diferentes regiones geográficas hacen de la arquitectura popular el punto de partida para su estudio y análisis. El interés por el conocimiento de la arquitectura popular pasa por indagar sobre la diversidad de su contexto, el cual tiene cuatro aspectos importantes para entender la arquitectura popular: el territorio ocupado por lo popular, el temporal visto como el surgimiento y el devenir, el socioeconómico respecto de las jerarquías sociales y el simbólico que se ocupa de los factores culturales. Finalmente, explica su posición con respecto a la situación actual de la arquitectura popular y la importancia de la intervención profesional para su revalorización.
Valor arquitectónico y simbólico del Pabellón Central de la Universidad Nacional de Ingeniería
Authors: Salazar Briones Sandra
Published: May 2020

El presente artículo permite identificar el valor simbólico y arquitectónico que tiene el Pabellón Central, el primer edificio construido en la Universidad Nacional de Ingeniería (UNI) en su nuevo local. La metodología aplicada en esta investigación está trazada por medio del análisis del contexto urbano e histórico, el estudio de las tipologías arquitectónicas y los nuevos materiales constructivos que hicieron de esta obra una de las más modernas de su tiempo. A través de la recolección de imágenes e información, se conocerá el papel que ha adquirido en la sociedad desde su origen hasta la actualidad. El objetivo de este estudio pretende contribuir en la difusión sociocultural del edificio emblemático de la UNI y evaluar el estado de su conservación actual.
Hacia un enfoque de conservación basado en entrelazamientos de Naturaleza y Cultura. Una mirada desde Japón en el contexto del Patrimonio Mundial
Authors: Ishizawa Escudero Maya Natalia
Published: May 2020

La Convención sobre la Protección del Patrimonio Mundial, Cultural y Natural aprobada por la UNESCO en 1972 se caracteriza por ser el único instrumento legal internacional con alcances para la conservación de sitios naturales y culturales con Valor Universal Excepcional. Sin embargo, en su implementación, el sistema se ha dividido en dos sectores: uno dedicado a la conservación de la naturaleza, y otro dedicado a la conservación de sitios culturales. Institucionalmente, en muchos países del mundo, como Perú o en Japón, se han generado sistemas de conservación del patrimonio en el que las instituciones a cargo obedecen a mandatos distintos y, en la práctica, no se relacionan entre sí. Dentro de esta problemática, el objetivo de este artículo es explicar las particularidades del sistema de conservación japonés y sus aportes conceptuales en el contexto internacional, los mismos que han permitido el desarrollo de talleres experimentales organizados por la Cátedra UNESCO sobre Enlaces Naturaleza-Cultura en la Conservación del Patrimonio de la Universidad de Tsukuba en Japón. En estos talleres se ha explorado la creación de capacidades de profesionales del patrimonio de la región Asia-Pacífico desde esta perspectiva.
Aproximación al modelo de gestión de Territorio-museo a partir de casos prácticos
Authors: Bringas Andrea Caridad , Vico Moreno Ruth
Published: May 2020

El reciente concepto de Territorio-museo surge en la segunda mitad de los años 90, como estrategia para definir un modelo de gestión basado en la musealización de un territorio con la finalidad de contribuir al desarrollo sostenible de un determinado espacio rural. En dicho modelo, se enfatizan: las intervenciones en la conservación del patrimonio natural y cultural, tangible e intangible; la participación activa y protagónica de la sociedad; y, la implementación de un plan de interpretación territorial. En el presente trabajo, se detallarán los orígenes del concepto en los ecomuseos y en las teorías de interpretación, y se explicarán las características de los Territorio-museo y los elementos que lo conforman. Finalmente, se hará un análisis comparativo de tres casos en Italia, España y Argentina, con el objetivo de visibilizar las características compartidas y las diferencias, en el marco de la amplitud y variabilidad regional de este innovador concepto. Todo ello, permitirá presentar una breve discusión y extraer conclusiones.
Núcleo Histórico de Bellavista como Zona Monumental: Análisis Urbano-Arquitectónico
Authors: Malpartida Pacaya Patricia
Published: May 2020

El Núcleo Histórico de Bellavista, diseñado por Luis Godín en 1747, desde hace unas décadas sufre un proceso de degradación que se da por abandono, deterioro, cambio de usos de suelo, demoliciones, entre otros factores. La Bellavista histórica de arquitectura colonial y republicana, con el paso del tiempo empieza a desaparecer en desmedro de su imagen urbana que posee un gran valor tanto para la historia del Callao como para la historia de Lima. Lamentablemente, poco se ha investigado sobre las edificaciones antiguas en este distrito. Por eso mismo, en este artículo daremos a conocer los estudios urbanos y arquitectónicos que identifican los valores del Núcleo Histórico de Bellavista con el fin de hacer posible una declaración de monumentos que ponga en valor la zona histórica del distrito y frenar, en lo posible, este proceso de degradación que atraviesa. La presente investigación se la dedico al distrito que me vio crecer, Bellavista, mi hogar.
Estructura, poesía, totalidad y fragmento en Machu Picchu y La mano desasida (¿1954?-1980) de Martín Adán. Aproximaciones hacia una nueva edición
Authors: Cavagnaro Farfán Franco
Published: May 2020

A partir de uno de sus viajes al Cusco, el poeta Martín Adán establece una oposición entre lo feble y la fortaleza, y traza una línea divisoria entre Lima y el Cusco. Es en este periodo que se da un cambio temático y de forma verbal en su obra con la publicación del primer fragmento de La mano desasida en 1961, cuyo referente es el Santuario de Machu Picchu. así la problemática de la totalidad y el fragmento desde sus correlatos textual y arqueológico. Esto como una forma de entender la vastedad del archivo que comprende al poema, el propio referente del canto, Machu Picchu, y otras estructuras prehispánicas: su carácter de patrimonio arqueológico inmueble, y considerando, al mismo tiempo, cómo son entendidas desde la poesía.
Vibration-based damage identification for reinforced concrete slab-type structures using fiber-optic sensors and random decrement technique
Authors: Pourrastegar Azita , Othman Hesham , Marzouk Hesham
Published: May 2020

This paper presents and evaluates a damage identification system for reinforced concrete (RC) slab-type structures based on non-destructive vibration testing, Random decrement (RD) signal processing technique, and embedded smart network of fiber-optic sensors. The proposed system aims to overcome the challenges associated with the use of electrical sensors and signal processing of noisy dynamic data. Two experimental modal analysis investigations have been conducted. First modal testing focuses on investigating the capability of fiber-optic sensors and Multi-channel random decrement (MCRD) processing technique to locate damage in RC slabs through changes in the first mode shape response with damage. The second modal testing focuses on the detection of damage intensity using the RD technique through the change in frequency and damping dynamic parameters.

The results show that RD technique can be used effectively to extract the free vibration response of RC slab-type structures; fiber-optic sensors are more sensitive to capture damage severity in comparison to electrical accelerometer sensors, especially, at steel yielding and failure load;  MCRD technique can be used effectively to generate mode shapes for RC slabs based on fiber-optic grating FBG sensors measurements. On the other hand, electrical strain gauges were noisy and it was difficult to obtain any measurable data; A damage identification system based on non-destructive vibration testing, MCRD  processing technique, and using an embedded smart network of fiber-optic sensors can estimate accurately the damage location through changes in the first mode shape.
Approximation of and by completely monotone functions
Authors: Loy Rick J. , Anderssen Robert Scott
Published: May 2020

We investigate convergence in the cone of completely monotone fu nctions. Particular attention is paid to the approximation of and by exponentials and stretched exponentials. The need for such an analysis is a consequence of the fact that although stretched exponentials can be approximated by sums of exponentials, exponentials cannot in general be approximated by sums of stretched exponentials.

doi:10.1017/S1446181120000012
PERAN PENGELOLA PAUD DALAM MENUMBUHKAN MINAT BACA ANAK USIA DINI MELALUI PROGRAM GERAKAN NASIONAL ORANG TUA MEMBACAKAN BUKU (GERNAS BAKU)
Authors: Sukmanandita Yulia
Published: May 2020

Kenyataan bahwa minat baca anak usia dini di Indonesia masih sangat rendah berdasarkan hasil survey Programme for Internasional Student Assesment (PISA) pada tahun 2015 menunjukkan bahwa Indonesia berada diurutan ke-64 dari 72 Negara dan menurut survey Badan Pusat Statistik (BPS) tahun 2015, 91,4% anak usia sekolah lebih suka menonton televisi dan 13,11% yang suka membaca. Pemerintah membuat Program Gernas Baku sebagai gerakan untuk mendukung inisiatif dan peran keluarga dalam meningkatkan minat baca anak melalui pembiasaan dirumah, disatuan paud, dan di masyarakat. Hal ini berlaku juga di Pos PAUD Kasih Bunda. Penelitian ini bertujuan untuk mengetahui bagaimana upaya pengelola Lembaga PAUD Kasih Bunda dalam menumbuhkan minat baca anak usia dini melalu Program Gernas Baku. Teori yang digunakan dalam penelitian ini adalah Minat Baca, Pengelola Lembaga PAUD, serta Gernas Baku. Dalam penelitian ini peneliti menggunakan metode deskriptif dengan pendekatan kualitatif. Sumber data dalam penelitian ini didapat dari sample penelitian yang diambil dari populasi di Pos PAUD Kasih Bunda yaitu 1 orang Pengelola, 3 Orang Tua, dan 3 peserta didik. Hasil penelitian menunjukkan bahwa Program Gernas Baku yang diterapkan di Pos PAUD Kasih Bunda memang dapat menumbuhkan minat baca anak. Minat baca anak usia dini terlihat dari rasa senang anak terhadap buku.
Evaluation of governance challenges associated with the exercise of fiduciary duties by the board members of the state-owned entities
Authors: Kgarabjang Tshegofatso
Published: May 2020

There are fundamental challenges encountered by the non-executive directors (board members) of state-owned entities in a course of exercise of fiduciary duties. These challenges are, inter alia, conflict of interests, failure to uphold the fundamental principles of corporate governance, lack of necessary skill and competencies, and this impact on the ultimate performance of the company. The article seeks to evaluate the potential challenges encountered by board members of state-owned entities in the course of exercise of their fiduciary duties. The results indicate that failure to comply with fiduciary duties may have drastic effects on a state as a shareholder and may lead to a decline in corporate governance of state-entity. The article will make a brief reference to fiduciary duties in terms of common law, the Companies Act, PFMA and King IV, secondly examine potential challenges and thirdly conduct a comparative approach with the international instruments with the aim of making recommendations/best practices. The article makes reference to various case laws dealing with fiduciary duties, journal articles, internet sources and textbooks, common law and legislations.
The sensitivity of GCC firms’ stock returns to exchange rate, interest rate, and oil price volatility
Authors: Alenezi Mariam , Alqatan Ahmad , Phiri Obby
Published: May 2020

This study seeks to investigate the sensitivity of stock returns to exchange rate, interest rate and oil price volatility in the Gulf Cooperation Council (GCC) countries. It employs both the multivariate ordinary least square (OLS) regression and the exponential generalized autoregressive conditional heteroscedastic in mean (EGARCH-M) models to analyse the data collected from Bloomberg and DataStream on the GCC countries (Bahrain, Kuwait, Oman, Qatar, Saudi Arabia and the United Arab Emirates) for the period January 2007 to June 2012. The study shows that stock returns in GCC countries are influenced by the exchange rate risk, interest rate risk and oil price risk. However, the exposure is highest for exchange rate risk and lowest for interest rate risk. While the effects of these risks were mixed, overall, exchange rate risk and oil price risk showed a positive and significant relationship as compared to the interest rate risk that showed a negative significant effect on firm values. The level of the effect of these risks also differed from country to country. Further, foreign operations and firm size had a significant influence on the extent of the firms’ exposure to all three risks. The study findings suggest that the volatility of stock returns affected by changes in the risk factors could indicate non-prioritisation of risk management by firms. This has implications in terms of consideration of the long-term exposure of firms to these three risks and thus, the need for effective risk management strategies.
DETERMINATION OF POOR COMPLIANCE WITH OSH RULES OF CONSTRUCTION WORKERS USING ORDINAL REGRESSION MODEL
Authors: AKBOĞA KALE Özge
Published: May 2020

Occupational accidents in the construction industry constitute one of the major problems in Turkey. The industry alone is responsible for 32.0% of all fatal industrial accidents from 1992–2015. Beyond precautionary efforts, workers need to participate and cooperate in the construction process to reduce the high number of accidents. The objective of this study is to provide an in-depth understanding of the underlying causes and motivations that affect the compliance of workers in following occupational safety and health (OSH) rules. A total of 482 workers were surveyed in 2016–2017. Cronbach’s alpha was used to measure the reliability of the dataset. Ordinal logistic regression was conducted to determine the parameters that affect the compliance of workers in following OSH rules. Results show that most construction workers do not believe in the following findings: companies should provide OSH training before starting work; focusing on OSH would increase work efficiency and quality; OSH training is effective in preventing occupational accidents; OSH training is effective in reducing the frequency of occupational accidents; and OSH training is important for the safe use of equipment. Thus, the safety culture should be developed first in order for workers to gain awareness, adaptation and their sustainability.
Tek Fazlı R600a Soğutkan Akışı İçin Mikrokanal Eşanjörün Matematiksel Modellemesi
Authors: BAŞARAN Anıl , YURDDAŞ Ali
Published: May 2020

Bu çalışmada, özellikle iklimlendirme sistemlerinde ön ısıtma/soğutma, aşırı kızdırma/soğutma gibi tek fazlı soğutkan akışının olduğu uygulamalar için mikrokanal eşanjörlerin matematiksel modellemesi deneysel doğrulamalı olarak ele alınmıştır. Çalışma akışkanının R600a olduğu panjurlu kanatlı mikrokanal eşanjörler için R600a’nın çıkış sıcaklığını, toplam ısı transfer kapasitesini ve entropi üretimini tahmin eden bir matematiksel benzetim modeli geliştirilmiştir. Modelin doğruluk hassasiyetini arttırmak için geçişlerdeki farklı kütle hızları ve uniform olmayan hava hızı modelde dikkate alınmıştır. Bu etkileri dikkate almak için literatürde yer alan diğer modellerden farklı olarak iki seviye ayrıklaştırma ile oluşturulan bir hesaplama sistemi modelde uygulanmıştır. Modelde mikrokanal ısı eşanjörünün ön yüzü hava akış bölgelerine bölünerek uniform olmayan hava hızları dikkate alınmıştır. Model sonuçlarını doğrulamak için deneysel çalışma yapılmıştır. Deneysel doğrulama sonucunda modelin, incelenen tüm test koşulları için çıkış sıcaklığını ±%10 aralığında bir ortalama mutlak sapma ile öngördüğü sonucuna varılmıştır. Mikrokanal ısı eşanjörünün, ısı transfer performansını tahmin etme kabiliyeti, deneylerle değerlendirilmiş, uniform olmayan hava hızının modele dahil etmenin, modelin doğruluk hassasiyetini arttırdığı görülmüştür. Mikrokanal ısı eşanjöründeki entropi üretim mekanizmaları incelenmiş ve akışkan akımı tersinmezliklerinin entropi oluşumuna katkısının, ısı transfer tersinmezliklerine kıyasla oldukça düşük olduğu tespit edilmiştir.
Konseling Behavioral dengan Teknik Sosiodrama Melalui Lesson Study Untuk Meningkatkan Self-Succorance
Authors: Ariandani Ni Putu Diah , Dantes Nyoman , Dharsana I Ketut
Published: May 2020

The first objective of this study was to know the extent of effectiveness of the implementation of behavioral counseling theory by using sociodrama technique to improve self-succorance of grade VII students of SMP Lab. Undiksha Singaraja, The second objective of this study was to know the difference of self-succorance between the students who were given behavioral counseling by using sociodrama technique and the students who were not given behavioral counseling by sociodrama technique on grade VII of SMP Lab.Undiksha Singaraja. This was an experimental study with non-equivalent pre-test post-test control group design. The population of this study was the students of grade VII of SMP Lab. Undiksha. The study sample was taken by using random sampling technique, in which it was found that 103 students had moderate and low self-succorance. From the 103 students who were selected as members of the sample, it was randomly selected 1 class as the experimental group and the other 1 class as the control group. The data collection method of self-succorance in the study used the obsevation method, interview, diary and self-cycles questionnaire of Likert scale. The analysis method of the hypothesis test used was the t-tes. The results of this study indicated that there was effectiveness of the implementation of Behavioral Counseling by using Sociodrama technique to improve self-Succorance of grade VII students of  SMP Lab. Undiksha, and there was a difference of self-Succorance between the students who were given behavioral counseling by using sociodrama technique and the students who were not given.Keywords: Behavioral counseling, sociodrama technique, self-succoranc
Pengaruh Model Konseling Behavioral dengan Teknik Modeling untuk Meningkatkan Self Autonomy
Authors: Jamilah Umi , Suarni Ni Ketut , Gading I Ketut
Published: May 2020

The purpose of this reseach was to know the effect of behavioral counseling modeing technique to improve the student’s self-autonomy of class X Akomodasi Perhotelan 5 at SMK Negeri 2 Singaraja. This reseach was designed as a quasi-experimental design, which used postest-only control group design as the resach design. Population in this reseach was the student’s of class X at SMK Negeri 2 Singaraja. the sample of this reseach was taken by using purposive sampling. Self autonomy data was collected throught questionnaire method, and the data obtained was in the from of interval data. To conduct the hypothesis test it was analyzed by using non-parametric statistical analysis technique (Mann-Whitney test). The result of Mann-Whitney test showed that the significance value which obtained was 0,001. This showed that the significane value obtained can be said as significane. Therefore, it can be concluded taht “ther was an effect of behavioral counseling modeling technique to improve the student’s self-autonomy of class X Akomodasi Perhotelan 5 at SMK Negeri 2 Singaraja” Keywords: Behavioral Counseling Model, Modeling technique, Self-Autonomy.
Efektivitas Model Konseling Behavioral Pavlov dengan Teknik Classical Conditioning untuk Meningkatkan Self Achievement
Authors: Azhar Dimas , Suranata Kadek , Dharsana I Ketut
Published: May 2020

This study aims to know: Effectiveness of behavioral counseling i. f. Pavlov with classical conditioning techniques through lesson study to improve self achievement. This research includes "quasi experiment". The experimental design used was Pretest Postest Control Group Design. The population of this study was the eleventh grade students of the Singaraja Undiksha Lab High School, totaling 105 people. Self-achievement data collection in this study using the self achievement questionnaire. Based on the t-test, the results of Fhit are 1.43 with a significance level of 5% with df1 = 2-1 = 1, df2 = 23-1 = 22 with Ftable 4.30, then Fhit <Ftable or 1.43 <4 is obtained. , 30. The value of ES = 0.09, ES is in the high category. The results of this study indicate that there is effectiveness in behavioral counseling i. f. Pavlov with a classical conditioning technique on the self-achievement of class XI students at Singaraja Undiksha Laboratory.Keywords: Behavioral counseling, Pavlov, self achievement, classical conditioning technique
Efektivitas Konseling Behavioral dengan Teknik Shaping untuk Meningkatkan Self Afiliasi
Authors: Teaningsih Ni Ketut Hefi , Suranata Kadek , Suarni Ni Ketut
Published: May 2020

The purpose of this study was to determine the effectiveness of behavioral counseling with shaping techniques to improve self affiliation 1st grade SMA N 4 Singaraja students. This experimental study used the Pretest Postest Control Group Design. The study population was students of class 1st grade SMA Negeri 4 Singaraja, Buleleng, Bali, which numbered 349. The study sample consisted of 58 students. Through random sampling techniques, 22 students were placed in the experimental group who received a treatment model of behavioral counseling with shaping techniques and 36 students were the control group. The data in this study were analyzed by inferential t-test statistics using JASP Version 0.7.5.5 software and continued with d’Cohen to calculate the level of effectiveness. The results showed that there was a difference in the self-affiliation of the experimental group students after taking the treatment with the control group self-affiliation to get t = 17.28 with p <0.001 then p <0.05. Effect Size (ES) testing through Dohen also shows the high level of effectiveness of the behavioral counseling model (ES = 4.7). These results prove that behavioral counseling with shaping techniques is effective to improve the self-affiliation 1st grade students of SMA N 4 Singaraja.Keywords: Behavioral Counseling, Shaping Technique, Self Affiliation
Успешное лечение аневризмы артериального протока: описание случая и краткий обзор литературы
Authors: Nefedova I.E. , Berishvili D.O. , Baryshnikova I.IU. , Manerova A.F.
Published: May 2020

Аневризма артериального протока (ААП) является редкой врожденной аномалией, чаще выявляемой у плодов в поздние сроки гестации и детей в возрасте до 2 мес. Мы представляем описание случая успешного хирургического лечения гигантской аневризмы открытого артериального протока, осложненной левосторонним гемотораксом у ребенка 1,5 мес жизни, массой тела 4,5 кг. При анализе литературы было выявлено, что большая часть хирургической резекции ААП с осложнениями и без них выполнялась из срединной стернотомии в условиях искусственного кровообращения (ИК), раздельной перфузии дуги аорты и нижних конечностей, ушиванием устья в случае неосложненной ААП или с помощью шунта Готта в обход аневризмы и закрытием заплатой шейки аневризмы из просвета аорты. У нашего пациента хирургическое вмешательство было выполнено из боковой торакотомии без применения аппарата ИК. Описание нашего случая является еще одним напоминанием о возможности развития редких фатальных осложнений при относительно простом нарушении физиологического развития ребенка открытом артериальном протоке.
Двуотточное левое предсердие и частично открытый атриовентрикулярный канал у ребенка
Authors: Kornouhov IU.IU. , Il`ina M.V. , Beliaeva M.M. , Hovrin V.V. , Il`in V.N.
Published: May 2020

Представлено наблюдение необычного варианта частично открытого атриовентрикулярного канала с двуотточным левым предсердием (ДО ЛП). Диагноз редкой аномалии у 10-летнего ребенка, занимавшегося спортом, был установлен при плановом обследовании с помощью двухмерной эхокардиографии и подтвержден с помощью магнитно-резонансной томографии. Было диагностировано раздельное двойное сообщение левого предсердия с левым желудочком и правым желудочком в сочетании с маленьким дефектом межпредсердной перегородки типа ostium primum и трехстворчатым левым атриовентрикулярным клапаном, при отсутствии признаков обструкции, а также значимой недостаточности клапанов. В связи с отсутствием какой-либо клинической симптоматики показаний к терапевтическому и хирургическому лечению не было установлено. Представленное наблюдение хорошо дополняет череду ранее сделанных публикаций ДО ЛП, при которых эта аномалия являлась элементом комплексных врожденных пороков сердца, а также иллюстрирует исключительную анатомическую вариабельность открытого атриовентрикулярного канала.
Authors: Risa Septia Dwi , Triyatno Triyatno , Febriandi Febriandi
Published: May 2020

Penelitian ini bertujuan untuk mengetahui (1) perubahan luas penggunaan lahan permukiman di Kecamatan Kuranji tahun 2007-2016; (2) pola permukiman penduduk di Kecamtan Kuranji tahun 2007 dan 2016; (3) pengaruh pertambahan jumlah penduduk terhadap perkembangan luas permukiman di Kecamatan Kuranji tahun 2007-2016. Jenis penelitian adalah deskriptif kuantitatif dengan menggunakan peta penggunaan lahan tahun 2007 dan 2016, data penduduk tahun 2007 dan 2016. Teknik analisis yang digunakan adalah overlay peta penggunaan lahan tahun 2007-2016, analisis tetangga terdekat dan regresi linear sederhana.

Berdasarkan hasil penelitian menunjukkan bahwa : (1) Perubahan luas penggunaan lahan permukiman di Kecamtan Kuranji tahun 2007-2016 adalah 226,56 hektar. Kelurahan Kuranji merupakan kelurahan yang paling tinggi tingkat perkembangan luas lahan permukimannya yaitu seluas 58,28 hektar (25,72%) dan Kelurahan Anduring merupakan kelurahan yang paling sedikit tingkat perkembangan luas lahan permukimannya yaitu seluas 9,47 hektar (4,18%), (2) berdasarkan teknik analisis tetangga terdekat diperoleh nilai dengan nilai T = 0,93 (2007) dan nilai T = 0,95 (2016) berarti pola persebaran permukiman di Kecamatan Kuranji Tahun 2007 dan 2016 adalah Acak (Random), (3) pertambahan jumlah penduduk berpengaruh terhadap perkembangan permukiman. Pertambahan jumlah penduduk memiliki pengaruh terhadap variabel perkembangan permukiman sebesar 47,9%.