bluuebunny/crossref_metadata_2025 huggingface dataset:
Incontinence in palliative care: assessment to promote dignity
Authors: Jackson Debra
Published: May 2022

This article will explore the district nurse (DN) role in caring for palliative service users and their responsibility to prepare them and their family members to understand the trajectory of their prognosis and the possible decline in urinary function and incontinence. Educating DNs to advise service users in appropriate management options and collaborating with the wider multidisciplinary team (MDT) to ensure service users' individual goals and aims are followed as closely as possible.

Urinary incontinence (UI) is not a natural part of the ageing process, although the prevalence of UI is increased as people age, through multi-morbidities, polypharmacy, cognitive decline, mobility limitations or life-limiting conditions. UI affects an individual's dignity and can cause a negative impact on self-esteem, and it is often accompanied by a perceived stigma that can lead to anxiety, depression and a reluctance to ask for help and advice.
The mass knee clinic: a cost–benefit analysis
Authors: Li Lily , Ganippa Haddon Paul Lionel , Nathwani Dinesh , Bhattacharya Rajarshi
Published: May 2022

Background/Aims

Many trusts struggle to meet the government-mandated referral-to-treatment target of 18 weeks. The mass knee clinic model is an innovative approach to elective service organisation, allowing large numbers of new patients to be seen in one day in a multidisciplinary setting. This study describes a cost–benefit analysis of the mass knee clinic in an NHS trust.

Methods

Data were taken from trust management regarding the number of patients seen in the clinic and the staff required to deliver it. Staff and non-staff costs were calculated using data from NHS England. The costs per appointment were calculated and the average number of patient visits required were compared to data from before the implementation of the clinic to find the associated cost savings.

Results

The average cost per appointment at the mass knee clinic was £98.52, with an average of 152.64 patients seen per clinic day. The mean number of patient visits required fell from 4.57 to 2.41 following the implementation of the clinic. Overall, the clinic can produce cost savings £29 335.43 per clinic day and £264 018.89 per year.

Conclusions

The mass knee clinic model can produce substantial cost savings and increase efficiency, allowing better management of waiting times and reducing reliance on outsourcing.
ACT NOW: a practical toolkit for amputation reduction
Authors: Robbie Jayne , Edmonds Mike , Phillips Anne , Odiase Charles , Beckwith Anita , Diggle Jane , Holmes Patrick , Grummitt John , Walker Kate
Published: May 2022

Foot problems are often associated with multiple limb-threatening comorbidities for people with diabetes. It has been suggested that many of these amputations could be avoided if foot ulcers are effectively detected, assessed, referred and rapidly treated in order to optimise healing. All healthcare professionals in both primary and secondary care can have a pivotal role to play to reduce major amputations by 50%. Adopting ACT NOW and using this tool routinely can reduce the unacceptably high volume of major amputations.
Toward non-metameric reflectance recovery by emulating the spectral neighborhood using corresponding color information
Authors: Safdar Muhammad , Emmel Patrick
Published: May 2022

In learning-based reflectance reconstruction methods, usually localized training samples are used to reconstruct spectral curves. The state-of-the-art methods localize the training samples based on their colorimetric color differences with the test sample. This approach is dependent on the working color space, color difference equation, and/or illuminant used, and it may result in a metameric match. This issue can be resolved by localizing the training samples based on their spectral difference with the test sample; however, this would require an already unknown spectral curve of the test sample. In this paper, use of corresponding color information to emulate the spectral neighborhood of the test color for non-metameric reflectance recovery is proposed. The Wiener estimation method was extended by (1) using two thresholds, (i) on the color difference between the test sample and the training samples under the reference illuminant and (ii) on the color difference between the corresponding color of the test sample and the training samples under another illuminant, to mimic the spectral neighborhood of the test sample within the gamut of the training data, and (2) also using the tristimulus values of the corresponding color in the regression. Results showed that the proposed extension of the Wiener estimation method improved the reflectance recovery and hence reduced the metamerism.
How do turbidite systems behave from the hydrogeological point of view? New insights and open questions coming from an interdisciplinary work in southern Italy
Authors: Rizzo Pietro , Severini Edoardo , Bucci Antonio , Bocchia Federico , Palladino Giuseppe , Riboni Nicolò , Sanangelantoni Anna Maria , Francese Roberto , Giorgi Massimo , Iacumin Paola , Bianchi Federica , Mucchino Claudio , Prosser Giacomo , Mazzone Domenico , Avagliano Dario , Coraggio Francesco , Caputi Antonella , Celico Fulvio
Published: May 2022

Turbidite successions can behave either as aquitards or aquifers depending on their lithological and hydraulic features. In particular, post-depositional processes can increase rock permeability due to fracture development in the competent layers. Thus, at a local scale, turbidite systems warrant further detailed investigations, aimed at reconstructing reliable hydrogeological models. The objective of this work was to investigate from the hydrogeological perspective a turbiditic aquifer located in southern Italy, where several perennial and seasonal springs were detected. Considering the complex hydrodynamics of these systems at the catchment scale, to reach an optimal characterization, a multidisciplinary approach was adopted. The conceptual framework employed microbial communities as groundwater tracers, together with the physicochemical features and isotopic signature of springs and streams from water samples. Meanwhile, geophysical investigations coupled with the geological survey provided the contextualization of the hydrogeological data into the detailed geological reconstruction of the study area. This modus operandi allowed us to typify several differences among the samples, allowing identification of sources and paths of surface water and groundwater, along with diffuse groundwater outflow along streams. As a final result, a hydrogeological conceptual model was reconstructed, underlining how at a very local scale the lithologic, hydraulic, and geomorphological heterogeneity of the studied relief can lead to an improved hydrogeological conceptual model compared to that of other turbidite systems. These results open new questions about the hydrogeological behavior of turbiditic aquifers, which could be pivotal in future research. In fact, these systems could support relevant ecosystems and anthropic activities, especially where climate change will force the research of new (and probably less hydrogeologically efficient) water sources.
Assessing media mergers and acquisitions: The power pyramids of regulatory cooperation
Authors: Afilipoaie Adelaida , Ranaivoson Heritiana
Published: May 2022

Due to the media goods’ dual economic and cultural role, merger and acquisition (M&A) assessments are complex and differ from M&As in other sectors. An additional layer of complexity is added to the assessment when various authorities are involved. An even more complicated matter is when the authorities have different remits. These authorities mostly comprise National Competition Authorities that enforce competition law, focused on economic considerations, and National Regulatory Authorities that enforce and oversee the application of media law, focused not only on setting rules and limitations on the media market but also on considering non-economic elements such as plurality. In certain countries, ministries and government authorities can intervene in these assessments.

There have been discussions on the need for cooperation between authorities, however, mostly at the international level. Thus, little is known about the current cooperation procedures at the national level. The article proposes a typology of cooperation at the EU member states level and the United Kingdom and introduces the concept of the ‘power pyramid’ to represent the hierarchical relationships between authorities. Cooperation proves that competition policy and media-specific regulation are intertwined and are complementary. Furthermore, the article shows that having more than one authority assessing media M&As leads to media pluralism being more often explicitly one of the criteria used in the assessments, and thus providing a more holistic approach.
Oscillation of half-linear differential equations with mixed type of argument
Authors: Džurina Jozef , Baculíková Blanka
Published: May 2022

This paper is devoted to the study of the oscillatory behavior of half-linear functional differential equations with deviating argument of the form

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Global smooth linearization of nonautonomous contractions on Banach spaces
Authors: Dragičević Davor
Published: May 2022

The main purpose of this paper is to establish a global smooth linearization result for two classes of nonautonomous dynamics with discrete time. More precisely, we consider a nonlinear and nonautonomous dynamics given by a two-sided sequence of maps as well as variational systems whose linear part is contractive, and under suitable assumptions we construct

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conjugacies between the original dynamics and its linear part. We stress that our dynamics acts on a arbitrary Banach space. Our arguments rely on related results dealing with autonomous dynamics.
"Falusi táncok"
Authors: Szőnyi Vivien
Published: May 2022

The doctoral thesis examines the transformation, social embeddedness, and functions of dance culture in a single North-Eastern Romanian village, Magyarfalu (Arini) populated by a Roman Catholic, Hungarian ethnic group. The transformation of dance life and dance repertoire of the local community is discussed in the context of ecological, political, economic, and sociocultural processes within the period of 1940–2010. Along with highlighting a dynamic relation between society and dance culture, this study aims to prove that the theoretical and practical frame of functionalism, the method of social anthropology, can be adapted for dance anthropological research. In opposition to comparative and formal analyses of dances, the doctoral research puts more emphasis on examining the dancing community, the social network that keeps the dance culture alive and how dance events fit into the wider system of customs. Three theoretical and conceptual systems defined the interpretation frame. Based on the assumptions of British functionalism, recognized in the field of social anthropology, dance culture was considered to be an adaptation system; in accordance with the interpretation methods of dance anthropology, dancing was analyzed as a sociocultural practice; and leaning on the capital theory of economic anthropology, dance was regarded as a resource. Having the arbitrary differentiation of the terms dance, dancing, and dance culture kept in mind, dance was interpreted as a total social fact which has organic connections to various elements of culture. The research was based on three hypotheses. The first suggestion is that a local dance culture is undergoing a continuous transformation in the context of various ecological, political, economic, and socio-cultural processes or events affecting the community. According to the second hypothesis, the dance culture is socially embedded, so there is a close interrelationship between the social organization and the dance culture of the given community. Finally, it began the analysis on the assumption that parts of the dance culture are organically connected to the culture as a whole, where they meet certain needs through their functional role. Based on all this, the dissertation basically sought the answer to what processes may be behind the transformation of Magyarfalu’s dance culture; how local society determines dance culture; what functions dance culture plays in the life of the individual and the community; and how all this can be examined with the theoretical and methodological tools of social anthropology.
A mindlin shell finite element for stone masonry bridges with backfill
Authors: Řeřicha Petr
Published: May 2022

Stone masonry bridges are difficult to analyse with commercial finite element (FE) packages for their specific heterogeneous composition. The stone arch is best modelled as a thick shell where there are predestined directions of tension failure, normal to the bed joints. A dedicated, very simple, Mindlin shell finite element is developed with five translational degrees of freedom per node. It features compatibility with linear isoparametric or constant strain elements for the backfill. Most bridges can be analysed with a sufficient accuracy assuming plain strain conditions. The element then simplifies to a Timoshenko beam element with three translational degrees of freedom per node. An application of the latter one to the bridge at Poniklá is presented.
Results of research on backlash compensation in a power electric drive by low-power electronic device
Authors: Samsonovich Semen L. , Fedotov Boris K. , Rozhnin Nikolay B. , Goryunov Roman V.
Published: May 2022

This article considers the feasibility of restoring and maintaining the kinematic accuracy of the support-rotary device drives by introducing a backlash compensation device into the control system. The power electromechanical drives of support-rotary device considered in this article contain two motors, the summation of the torques of which is carried out on a common output shaft. It is shown that the restoration of the required kinematic accuracy of the drives can be achieved by introducing one of two variants of an electronic device for backlash compensation into the control system. In the first variant, equal and opposite displacement signals are introduced into the control signals of the motors. The second variant introduces an electronic cross-connections backlash compensation scheme was into the control system. The study of the operation of the support-rotary device drive system with two backlash compensation devices carried out by a simulation method showed that the use of a cross-connection scheme is the most preferable and effective.As a result of the research, it was shown that the introduction of an electronic backlash compensation device into the control system makes it possible to ensure the operability of the power electromechanical drives of a support-rotary device with initial kinematic accuracy.
Editorial
Authors: Elías Caro Jorge  Enrique
Published: May 2022

Editorial N° 20 2013
La política exterior de Chile, 1990-2009. Del aislamiento a la integración global.
Authors: Trejos Rosero Luis Fernando
Published: May 2022

Reseña del libro La política exterior de Chile, 1990-2009. Del aislamiento a la integración global. Editado por Mario Artaza y César Ross
Las Cucharas y Leticia: dos sitios arqueológicos tardíos en el Canal del Dique. Avance de investigación
Authors: Carvajal Contreras Diana Rocio
Published: May 2022

La información de este artículo provino del proyecto de investigación en curso “Evaluación Zooarqueológica de concheros cercanos al Canal del Dique, Fase Inicial”. Se procedió a la ubicación de los puntos identificados por Macchi en 1998, registrando dos sitios con materiales posteriores al Formativo: las Cucharas y Leticia. Las evidencias se asociaron a fechas entre los siglos XIII a XIX. Uno de ellos tal vez esté relacionado con las actividades de reapertura del Canal bajo la dirección de G.M. Totten. Por otro lado, los taxones de moluscos indicaron que las personas que habitaban en los sitios arqueológicos, principalmente Leticia, se desenvolvían en un ambiente costero con diversos hábitats de playa arenosas, playas fangosas, manglar, zonas rocosas y de alta energía, zonas intermareales o hábitats de arena-cascajo, fondo mixto, pradera de pastos, y pradera de macroalga.
Digital Transformation of the Silk Industry of Assam
Authors: Hazarika Indrani
Published: May 2022

The case study on the silk industry of Assam gives an overview of the industry, background, production process and highlights the key issues, which the industry is currently facing. In order to ensure strategic success, the traditional silk industry will have to effectively cope up with the digitalization challenge in the market for customer discovery. The raw material is locally available but limited in supply and there is no alternative source to cater the needs of the weavers. Therefore, the weavers are bound to pay high prices of raw materials. Though the cost of raw material is increasing, the weavers cannot increase the price of the products due to availability of cheap synthetic silk in the market and, they are compelled to compromise with the profit margin of the product. The entire silk industry of Assam is passing through a stagnation period not only because of the financial crisis  but also due to rising prices and dearth of raw materials. This has resulted in aggravating the losses of the silk industry, as the weavers have to sell the products at the older price while procuring the raw material at the newly fixed price. The existing silk industry of Assam should go for complete digitalization through interconnected ecosystem, disrupt, and reshape the existing industry by identifying the technology associated with the business process and aligning with the business strategy. A digital culture needs to be fostered in the entire industry
Blockchain Technological Transformation from a Centralized into a Decentralized Ecosystem: BlockCity Is Rising
Authors: Hamzaee Reza G
Published: May 2022

Blockchain technology has been considered more seriously in the 21st century than ever for some time till eventually it was flourished through evolution of IoT, or Internet of Things, and the first well defined cryptocurrency, namely Bitcoin. Unlike what most people link blockchain technology to cryptocurrency, blockchain technology is applicable to many businesses, commerce, insurance, banking, healthcare industry, etc., as well as cryptocurrency. Bitcoin’s extension into the 21st century’s monetary system was - and will continue to be - remembered as a historical turning point of the medium of exchange, store of value, and unit of account, among other desirable properties of money. The authors in this research paper, given their extensive exposure to both related research sources, activities, and MIT’s Intensive Executive Management Program on Blockchain Technology, and most importantly their recent partnership with 369 Smart Chain’s BlockCity, are incentivized to provide more clarity to the global community as to this rapidly emerging platform in the world. The authors have concluded that the blockchain technology is another revolution inside the capitalistic ecosystem for imposing its powerful forces in the conversion of centralized businesses into somewhat more decentralized, where competition and efficiency would be more established than otherwise. There will be more reliable information, permanently stored on electronic ledgers, connected to nodes merged with those already accessible through the blockchain platform, operated by entrepreneurs, such as BlockCity, just as an example.
Three-dimensional numerical study of the reactive powder concrete segments in tunnel lining
Authors: Abbas Hajer Satih , Al-Rubaye Maadh Imad Salman , Jaafer Sarra’a Dhiya’a , bassam Bassam farman , Alkasassbeh Abdelmajeed
Published: May 2022

The tunnel lining systems act as lines of defence against the forces and geotechnical situations. The use of precast concrete tunnel linings (PCTLs) has been escalating due to its effective and economical installation process. The tunnels usually suffer from the premature deterioration due to corrosion of the reinforcement and thus need maintenance. Corrosion leads to the distress in PCTL leading to the cracking and finally the scaling of concrete. This study aims to assess the structural durability performance of reactive powder concrete (RPC) as the material of tunnel lining segments compared to reinforced concrete (RC) and high performance concrete (HPC). The numerical findings indicated that the maximum load capacity of PRC-PCTL segments was greater than that of the corresponding RC and HPC segments. Regarding the findings, PRC is a very significant option for conventional segments. The high strength of PRC can decrease the thickness of the PCTL segments, resulting in the decreased material cost. Also, PRC-PCTL segments can eliminate the laborious and costly production of RC segments and mitigate the corrosion damage and thus enhance the service life of lining segments.
Students and academicians views on the engineering curriculum and industrial skills requirement for a successful job career
Authors: Gope Deepayan , Gope Aditya
Published: May 2022

Due to rapid advancement of technology, engineers should have a set of engineering skills. The basic knowledge about engineering skills should be imparted during graduation. In this study, an attempt is made to assess the gap between the present course curriculum that engineering institutions are exposing their engineering students and the skills required by the industries. Views of engineering students and academicians are obtained through questionnaires and analyzed using statistical tools. The results revealed that strong analytical ability, able to adapt and learn new technology, problem-solving within stipulated period or deadlines, and work promotion are the most important factors for a successful future job performance. The study also reveals that a significant gap exists between learning skills like communication, systematic work plan, and furtherance of work done. It is also seen that the use of modern tools and knowledge up-gradation is important to acquire many required industrial skills for a successful job career and the present curriculum is not effective to impart training on these aspects.
Isocitrate dehydrogenase 1 mutation in cholangiocarcinoma impairs tumor progression by sensitizing cells to ferroptosis
Authors: Su Li , Huang Yi , Zheng Lei , Zhu Zhifa , Wu Yue , Li Ping
Published: May 2022

The present study intends to clarify the hypothesis that isocitrate dehydrogenase 1 (IDH1) mutation in cholangiocarcinoma impairs tumor progression by sensitizing cells to ferroptosis through the in vitro and in vivo experiments. Cholangiocarcinoma RBE cell line was transfected with IDH1 R132C mutation plasmids and treated with erastin to induce ferroptosis, which were then microscopically photographed. Cell viability rate was calculated by trypan blue staining. The lipid ROS level was determined by using flow cytometer. The BALB/c nude mice were injected subcutaneously with IDH1 knockout (KO), WT, or R132C mutation cell line, followed by injecting erastin intraperitoneally. The tumor tissue was surgically separated for the measurement of tumor volume and weight. The results showed that IDH1 mutant RBE cell line are sensitive to erastin-induced ferroptosis, evidenced by the increased number of propidium iodide-positive cells, the decreased cell viability, and increased lipid ROS level. However, current targeted inhibitors of IDH1 mutation (AG120 and IDH305) reversed these effects caused by IDH1 mutation. The in vivo experiment showed that IDH1 mutation in cholangiocarcinoma impairs tumor progression by sensitizing cells to erastin-induced ferroptosis. This study indicated that IDH1 mutation in cholangiocarcinoma impairs tumor progression by sensitizing cells to erastin-induced ferroptosis.
Second-tier strategies in newborn screening – potential and limitations
Authors: Gramer Gwendolyn , Hoffmann Georg F.
Published: May 2022

Newborn screening (NBS) is a public health measure to identify children with treatable disorders within the first days of life allowing presymptomatic treatment. It is the most successful measure of secondary medical prevention and part of public health programs in many countries worldwide. Application of second-tier strategies in NBS allows for increased specificity and consecutively a higher positive predictive value. Second-tier strategies can include analysis of specific biomarkers for a target disorder or may be based on molecular genetic analyses. Improving the quality of NBS, for example by second-tier strategies, is of utmost importance to maintain the high acceptance of NBS by families – especially as an increasing number of target disorders is being consecutively included into NBS programs.
Influence of chemical reaction on MHD Newtonian fluid flow on vertical plate in porous medium in conjunction with thermal radiation
Authors: Zhang Juan , Wang Fuzhang , Tamoor Muhammad , Kamran Muhammad , Farooq Aamir , Rehman Sadique , Aljohani Amnah S. , Khan Ilyas , Alkhatib Soliman , Ahmad Hijaz
Published: May 2022

Our key objective in the present work is to elaborate the concept of activation energy in chemically reactive flow with the help of modeling and computation. The model investigated is fluid flow over a vertical cylinder in the porous medium with chemical reaction and radiation effect. The similarity transform converted the resulting constitutive equations and partial differential equations (PDEs) into ordinary differential equations (ODEs). The resulting non-linear momentum, heat transfer, and mass transfer coupled equations are computed with the Range–Kutta–Fehlberg method. Both assisting and non-assisting buoyant flow conditions are considered, and observed numeric solutions vary with the transport properties. Characteristics of momentum, heat, and concentration under the applied boundary conditions are analyzed. In addition, the increment in activation energy parameters boosts the Lorentz force and mass transfer rate.
S. An-Sky’s The Dybbuk and the Process of Jewish American Identity in 1920s San Francisco
Authors: Wood Warren C.
Published: May 2022

In October 1928, an amateur troupe at San Francisco’s Temple Emanu-El performed the most famous play of Yiddish theater, The Dybbuk by S. An-sky (or Ansky). This production, only the third English-language staging of the play in the United States, was a signal event in the evolution of Jewish American identity in California and across the West. The players were a mix of elite San Francisco Jews of Western European descent and recent immigrants from Eastern Europe steeped in Yiddishkait, an approach to Jewish life that sought to transform and fortify the commonplace language and culture of Eastern European Jewry into a growing range of artistic, literary, intellectual, and social movements. The director, Nachum Zemach, had worldwide renown as an artist in Yiddish theater. The backers of the production had intended to bring about a revitalization of Jewish life in the city and the unification of a Jewish community splintered along lines of class, regional origin, and religious practice. Instead, the performance of the play became a catalyst for legitimizing the ongoing process of creating and recreating American Jewish identity out of a variety of cultural, social, and religious practices.
Clinical experience following implementation of routine SPECT-CT imaging following 131-iodine administration for thyroid cancer
Authors: Ahmadi Sara , Coleman Alexandra , de Morais Nathalie Silva , Landa Iñigo , Pappa Theodora , Kang Alex , Kim Matthew I , Marqusee Ellen , Alexander Erik K
Published: May 2022

Background

Planar scintigraphy has long been indicated in patients receiving I-131 therapy for thyroid cancer to determine the anatomic location of metastases. We studied our experience upon implementing additional single-photon emission (SPECT)-CT scanning in these patients.

Method

We performed a retrospective study of consecutive adult patients with newly diagnosed thyroid cancer treated with I-131 between 2011 and 2017. Radiologic findings detected with planar scintigraphy alone vs those identified with SPECT-CT scanning were primary endpoints.

Result

In this study, 212 consecutive patients with thyroid cancer were analyzed in two separate cohorts (107 planar scintigraphy alone and 105 planar scintigraphy with SPECT-CT). The addition of SPECT-CT resulted in more findings, both thyroid-related and incidental. However, we identified only 3 of 21 cases in which SPECT-CT provided an unequivocal additional benefit by changing clinical management beyond planar scintigraphy alone. No difference in the detection of distant metastatic disease or outcome was identified between cohorts.

Conclusion

Synergistic SPECT-CT imaging in addition to planar nuclear scintigraphy adds limited clinical value to thyroid cancer patients harboring a low risk of distant metastases, while frequently identifying clinically insignificant findings. These data from a typical cohort of patients receiving standard thyroid cancer care provide insight into the routine use of SPECT-CT in such patients.
Machine learning identifies baseline clinical features that predict early hypothyroidism in patients with Graves’ disease after radioiodine therapy
Authors: Duan Lian , Zhang Han-Yu , Lv Min , Zhang Han , Chen Yao , Wang Ting , Li Yan , Wu Yan , Li Junfeng , Li Kefeng
Published: May 2022

Background and objective

Radioiodine therapy (RAI) is one of the most common treatment solutions for Graves’ disease (GD). However, many patients will develop hypothyroidism as early as 6 months after RAI. This study aimed to implement machine learning (ML) algorithms for the early prediction of post-RAI hypothyroidism.

Methods

Four hundred and seventy-one GD patients who underwent RAI between January 2016 and June 2019 were retrospectively recruited and randomly split into the training set (310 patients) and the validation set (161 patients). These patients were followed for 6 months after RAI. A set of 138 clinical and lab test features from the electronic medical record (EMR) were extracted, and multiple ML algorithms were conducted to identify the features associated with the occurrence of hypothyroidism 6 months after RAI.

Results

An integrated multivariate model containing patients’ age, thyroid mass, 24-h radioactive iodine uptake, serum concentrations of aspartate aminotransferase, thyrotropin-receptor antibodies, thyroid microsomal antibodies, and blood neutrophil count demonstrated an area under the receiver operating curve (AUROC) of 0.72 (95% CI: 0.61–0.85), an F1 score of 0.74, and an MCC score of 0.63 in the training set. The model also performed well in the validation set with an AUROC of 0.74 (95% CI: 0.65–0.83), an F1 score of 0.74, and a MCC of 0.63. A user-friendly nomogram was then established to facilitate the clinical utility.

Conclusion

The developed multivariate model based on EMR data could be a valuable tool for predicting post-RAI hypothyroidism, allowing them to be treated differently before the therapy. Further study is needed to validate the developed prognostic model at independent sites.
Thyroid autoimmunity in Greenlandic Inuit
Authors: Noahsen Paneeraq , Rex Karsten F , Bülow Pedersen Inge , Mulvad Gert , Florian-Sørensen Hans Christian , Pedersen Michael Lynge , Andersen Stig
Published: May 2022

Objective

This study aimed to provide the first data on the occurrence of thyroid autoimmunity among Inuit in Greenland, a distinct ethnic group who is not iodine deficient.

Design

This study is a population-based cross-sectional study.

Methods

Data were collected in Nuuk in West Greenland and in Ammassalik district in East Greenland. Information on lifestyle, diet and diseases was obtained using questionnaires. Thyroid peroxidase antibody (TPOAb), thyroglobulin antibody (TGAb) and thyroid-stimulating hormone (TSH) were measured in serum. Iodine and creatinine were measured in spot urine samples.

Results

The participation rate was 95% with 434 Inuit participants; 75% were smokers. Iodine excretion was 169 µg/24 h in urban West Greenland, 224 µg/24 h in the main town and 228 µg/24 h in settlements in rural East Greenland. TPOAb, TgAb or either of these was measured in the serum from 3.7, 5.9 and 8.3% of participants, respectively. TPOAb or TgAb was found in 9.3% of Inuit women and 7.5% of men and more frequently, in East Greenland Inuit with the higher iodine excretion (P  = 0.02). There was some evidence suggesting that thyroid autoimmunity was more frequent among non-smokers (12.5%) compared to smokers (7.0%). Harbouring a thyroid autoantibody was most frequent in participants with TSH above 3.6 mIU/L (P  < 0.001).

Conclusion

Thyroid autoantibodies were rare among Greenland Inuit. While iodine nutrition was associated with autoimmunity similarly to other ethnic groups, the influence of sex and smoking was limited. This could suggest genetic component in Inuit, but the impact of cold, selenium and persistent organic pollutants needs to be elucidated.
Older People: A Counterweight to Consumer Hedonism in Society? Analysis of Consumption Preferences
Authors: Rapolienė Gražina , Mikulionienė Sarmitė
Published: May 2022

The Lithuanian consumer society is evolving, but we know little about it. On the one hand, previous research shows that it is a survival society that prioritizes functional needs, on the other hand, there are indications that a segment of consumers oriented towards self-expression is forming in Lithuania. Since consumption is both a consequence and a factor of class stratification, it is important to know whether (and how) it contributes to the strengthening of the social otherness of the group. The aim of this article is to find out whether (and how) consumption attitudes of older people differ from those of other age groups in Lithuania and what they are in the context of consumption values. In this study we analyzed the data of the representative Lithuanian population survey TNS Atlas (2012, N = 1847), divided into age groups (15–29, 30–44, 45–59, and 60–75 years). One-way analysis of variance (ANOVA) was performed for the comparison of consumption preferences, post hoc criteria and Spearman coefficient were applied, and the typology of values was used for the analysis of the content of statements. The results of this research showed that consumption attitudes of the Lithuanian population are not highly differentiated according to age, the attitudes of the oldest respondents (60–75 years old) differ little from others. The entire population aged 45–75 is more characterized by a combination of conservative and altruistic-ecological attitudes than the younger ones (18–44 years old), less characterized by openness to innovation and the pursuit of social self-enhancement. Although the differences in attitudes according to age are not bright in quantitative terms, in terms of content, there is a noticeable detachment of the older population from the refined consumer community.
МЕХАНІЗМИ ПРОВАДЖЕННЯ РЕГІОНАЛЬНОЇ ПОЛІТИКИ ІННОВАЦІЙНОГО СПІВРОБІТНИЦТВА НА ОСНОВІ СТИМУЛЮВАННЯ ПОПИТУ ТА ПРОПОЗИЦІЇ ІННОВАЦІЙ
Authors: Єрмакова О.
Published: May 2022

Вступ. Регіони мають потужний потенціал інноваційного розвитку. В умовах реформування місцевого самоврядування для України особливо актуальним є питання формування регіональної інноваційної політики, оскільки забезпечення інноваційної складової є необхідною передумовою економічної спроможності громад.Проблематика. Світовий досвід свідчить, що інноваційний розвиток регіонів потребує формування регіональних інноваційних систем та взаємозв’язків між усіма їх учасниками. В умовах реформи децентралізації в Україні співробітництво регіонів стає одним із інструментів їхнього соціально-економічного та інноваційного розвитку. Водночас цей інструмент недостатньо використовується в сфері інноваційної діяльності.Мета. Розробка методичних і прикладних засад впровадження механізмів інноваційного співробітництва на основі стимулювання попиту та пропозиції інновацій в регіонах України.Матеріали й методи. Інформаційною базою дослідження стали аналітичні матеріали ОЕСР, інноваційні брокерські платформи підприємств та регіонів країн світу, наукові праці провідних вітчизняних та зарубіжних вчених, даніДержавної служби статистики України, вивчені методами теоретичного узагальнення, аналізу та синтезу, системного та економіко-статистичного аналізу.Результати. Запропоновано концептуальні засади організації процесу взаємодії суб’єктів попиту та пропозиції інновацій, здійснено систематизацію відповідних механізмів, діагностику стану інноваційного співробітництва між суб’єктами попиту та пропозиції інновацій в регіонах України, класифіковано ключові характеристики механізмів регіонального брокериджу в сфері інновацій та їх варіації для об’єднаних територіальних громад, розроблено механізм регіонального брокериджу, орієнтований на стимулювання суб’єктів інноваційного попиту до співробітництва.Висновки. Механізми регіонального брокериджу сприяють посиленню інноваційної спроможності регіонів шляхом подолання фрагментарності їхніх інноваційних систем.
Application of a neural network for determining the parameters of a transformer elimination circuit under the conditions of non-invasive monitoring
Authors: Reva Ihor , Todorov Oleh , Bezzub Maksim
Published: May 2022

Purpose. Application of a specially constructed neural network with the task of identifying the parameter substitution scheme in non-invasive monitoring conditions.
Methodology. Use of electrical measurement methods by non-invasive monitoring, methods of identification and training of neural networks based on anterior and back propagation error, NARX networks.
Findings. The power transformer is an important object of the power system of the electric shop substation. At the same time, frequent transitions from underload to partial overload mode are possible, which creates preconditions for the development of undesirable phenomena in transformers. Monitoring of the power transformer based on control of its substitution scheme, allows to pass to control of its basic parameters irrespective of an operating mode. Non-invasive monitoring works well in the context of the task, because research shows that the parameters of voltage and current, which it operates well reflect the dependence on changes in the parameters of the substitution scheme. Based on T equivalent the substitution scheme can detect and predict changes in parameters substitution schemes according to the parameters of the current and voltage regime flowing in this system. Many neural networks will work out the calculation of electrical and electrotechnical  equivalent circuits as a task of identifying the parameters of electrical circuits in static conditions. In the process of identification, the ability of neural networks of different designs to identify one of the substitution scheme parameters, to resist damage was tested, which corrected the value of an unknown parameter. The experiment made it possible to obtain data for comparing the effectiveness of various architectures of neural networks in relation to the real parameters of the equivalent circuit. Concretizing the obtained results, we say that the NARX architecture is able to identify parameters in standard modes for all elements of the substitution circuit, which further opens up opportunities for its improvement in the calculation of nonlinear elements of the transformer when operating in a saturated state.
Originality. It is established that the neural boundaries studied in the work are able to determine the parameters of the replacement circuit of a transformer or electric machine in static operating modes, which allows in the future to monitor the state of windings and magnetic circuit according to their values.
Practical value. Using a neural network in the monitoring system allows you to get clear values of the equivalent circuit parameters, regardless of the mode, the proposed method significantly reduces the amount of time spent on monitoring the transformer parameters, allows you to control the power level, and, if necessary, reduce the amount of information required for the transformer monitoring.
Figurative Framing Around Pandemic Discourse: From Metaphorical Wars on Coronavirus to Wars on Anti-Vaxxers
Authors:   Volgograd State University, Skrynnikova Inna , Astafurova Tatiana ,   Volgograd State University
Published: May 2022

The current paper deals with metaphorical framing of the COVID-19 pandemic and public response to it in the public and media discourse. Being one of the most dramatic global challenges of the third Millennium, the COVID-19 pandemic spurred transformation in social order, economic/business relationships and dramatic growth in social anxiety and tensions, mistrust and discriminatory measures. It has inevitably found its reflection in language and related discursive practices, which rely heavily on discourse metaphors. When being systematically employed, they affect people's views of events, situations and decisions they subsequently make. The present paper focuses primarily on the COVID-induced discourse changes that create new metaphorical framings and re-shape the familiar ones. The repertoire of elicited discourse metaphors framing the coronavirus discourse communicates the changing combating strategies referred to by the authors as globalist, nationalist and discriminatory. By drawing on specially compiled subcorpus of public and media texts, the paper reveals the conceptual and inferential structure of the concept of the COVID-19 pandemic and discusses the possible implications of activating various pandemic-related frames. The study stresses that the discursive construction of the coronavirus pandemic mirrors the dynamic nature of the pandemic itself as well as the measures to combat the insidious virus taken by national governments, the spread of misinformation and fake news as well as the split in the society and discrimination of certain groups (vaccine deniers/anti-vaxxers). Acknowledging the prevalence of military metaphors in the pandemic-related discourse, the authors claim that metaphorical framing serves as a crucial conceptual tool to communicate the gradual transition from war on COVID-19 to war of vaccines and ultimately to war on out-groups (vaccine deniers, anti-vaxxers).
Phonetic and Phonemic Laws in Modern Historical and Phonological Studies (Linguistic Historiographical Aspect)
Authors:   Donbass State Teachers' Training University, Glushchenko Vladimir , Orel Anna ,   Donbass State Teachers' Training University, Piskunov Alexander ,   Donbass State Teachers' Training University
Published: May 2022

The problem of phonetic and phonemic laws reconstruction in the works of linguists of the 19 th – 21 st centuries was investigated. The study demonstrated the significance of the concepts of sound changes based on the postulate of the phonetic law by E.D. Polivanov (convergent-divergent theory of sound changes), R.O. Jacobson (phonological mutations), which became the foundation of historical phonology, due to which V.K. Zhuravlev completed the construction of the paradigm of historical (diachronic) phonology. It was shown that the phonetic variability and variability of the sound system of the language were considered as a consequence of the action of certain linguistic laws. Definitions of the terms "phonetic law" and "phonemic law", the establishment of their main differences proved the thesis about the connection of synchrony and diachrony which allowed us to interpret the phenomena of the history of the sound systems of the Proto-Slavonic and East Slavonic languages. V.K. Zhuravlev and Yu.Ya. Burmistrovich's contribution to the study of these issues in relation to the history of East Slavonic languages were described in detail. The work used an actualistic method which allowed us to consider a particular linguistic concept from the point of view of contribution and significance for linguistics in comparison with previous achievements. A.S. Orel presented the material on phonemic laws in works on the sound system history; A.V. Piskunov – the material on the role of phonetic law and analogy, linguistic reconstruction in the works of Kharkiv, Moscow, Kazan schools scientists of; V.A. Glushchenko – the material on understanding the essence of phonetic law in the works of Kharkiv and Moscow schools scientists.
Study of Sorption Properties of Carbon Nanotubes for Water Purification from Inorganic Impurities
Authors:   Volgograd State University, Zaporotskova Irina , Ermakova Tatyana ,   Volgograd State University, Kakorina Olesya ,   Volgograd State University, Akatiev Vladimir ,   Volgograd State University, Kamyshanova Lilia ,   Volgograd Institute of Management, Branch of the Russian Presidential Academy of National Economy and Public Administration
Published: May 2022

Studies of adsorption properties of carbon nanotubes with respect to inorganic molecules have been carried out. Theoretical quantum-chemical calculations of the interaction of the most common impurity molecules in water with carbon nanotubes were made. Analysis of modern water purification filters shows the general disadvantage of all modern filters – they clean water only from a certain type of pollution. In order to clean water from a wide range of different pollutants, it is necessary to carry out multistage purification, with different types of filters, which is very resource intensive, and takes quite a long time. Using carbon nanomaterials as filters will solve this problem. For the study, the most common inorganic substances were chosen, which are most often found in drinking water: calcium chloride CaCl2, magnesium chloride MgCl2, sodium chloride NaCl, calcium carbonate CaCO3, magnesium carbonate MgCO3, calcium sulfate CaSO4, magnesium sulfate MgSO4. Processes of adsorption interaction of selected inorganic impurity molecules to the surface of single-layer carbon nanotubes of type (6,6) were investigated. Surface profiles of potential energy of interaction of molecules (calcium, magnesium and sodium salts) with surface of carbon nanotube are constructed. The positive effect of carbon nanostructures on the process of water purification from inorganic impurities is shown, meaning the possibility of using CNT as a filter for water purification.