bluuebunny/crossref_metadata_2025 huggingface dataset:
Avaliação de risco do pé diabético em uma unidade básica de saúde
Authors: Almeida Danilo José de Almeida , Lima Anaisa de Almeida , Cavalcanti Jéssica Nóbrega , Barbosa Maria Luiza de Souza Miranda , Sá Jéssica Rodrigues Correia e
Published: May 2022

De acordo com a Organização das Nações Unidas, 70% das amputações realizadas no Brasil são decorrentes do Diabetes Mellitus. Existem evidências que indivíduos com o diabetes mal controlado ou não tratado, desenvolvem consequências como aumento do número de hospitalizações, aumento de eventos cardiovasculares, cerebrovasculares, cegueira, insuficiência renal e amputação não traumática do membro inferior. Relato de experiência: No período de maio a junho de 2018, os estudantes da graduação de medicina realizaram algumas atividades para avaliar e cuidar do pé diabético dos usuários da Unidade Básica de Saúde (UBS) de Jardim Fragoso I, localizada no município de Olinda, PE. Participaram das atividades 21 usuários da UBS que apresentavam o diagnóstico precoce de DM, as atividades propostas foram rodas de conversa com orientações e cuidados com o pé diabético e em seguida foi realizada uma avaliação através da ficha de Avaliação e Rastreamento de Dor Neuropática, Perda da Sensibilidade Protetora e Doença Arterial Periférica para Atenção Primária em Saúde. A alteração mais significativa identificada neste estudo, foi a redução da sensibilidade protetora plantar. Conclusão: A partir desta experiência, identifica-se a necessidade de realizar práticas de prevenção secundária na UBS voltadas para a pessoa diagnosticada com DM, incluindo o rastreamento do risco de ulceração. Por ser coordenadora do cuidado, ordenadora da Rede de Atenção à Saúde e porta de entrada do Sistema Único de Saúde (SUS), este serviço gera impactos relevantes na melhoria do prognóstico e redução de complicações referente às doenças crônicas.
Literatura de cordel como ferramenta de inclusão no processo de imunização
Authors: Cortez Isabelly Regina Bezerra de Albuquerque , Pereira Nayza Lorraynny de Brito , Pereira Nayhara Carlla de Brito , Sobreira Filho Pedro Augusto Figueirôa , Oliveira Tharcia Kiara Beserra de
Published: May 2022

Objetivo: Descrever a ação “Literatura de cordel como ferramenta de inclusão no processo de imunização” realizada na Unidade Básica de Saúde – Rio Doce V, que enfatiza a importância da vacinação na prevenção de doenças e diminuição da mortalidade, utilizando a literatura popular como impulso para propagar a informação com linguagem informal e criativa. Espera-se que esta experiência possa ser reproduzida em outros cenários, respeitando a cultura popular. Relato de Experiência: O projeto foi desenvolvido na UBS Rio Doce V etapa e contou com a participação dos funcionários, preceptor do campo de estágio e população. A priori realizou-se um esboço do que seria inserido na unidade, a logística do compartilhamento da informação para população e como o conteúdo seria absorvido, visto que o público principal são as famílias e as crianças da unidade. Com o cordel produzido, foi criado um painel adesivo com alusão à ideia de que família protegida contra doenças é família vacinada, e inserido em um contexto nordestino. Foi observado que a população e a equipe de saúde aderiram de forma significativa ao projeto. Como podemos demonstrar através de relatos da equipe profissional que atua na UBS onde inicialmente o trabalho foi desenvolvido. Considerações finais: Através do presente estudo, almejou-se desempenhar função de promoção e prevenção da saúde na comunidade, implantar estratégias que atuem na busca de instruções para a população local com conteúdos culturais, claros e acessíveis. Estamos convictos que desempenhamos tal atividade eivados de comprometimento com a melhoria da comunidade, contribuindo para a construção e fortalecimento do Sistema Único de Saúde.
Diagnóstico sequencial de duas mal formações arteriovenosas cerebrais
Authors: Tavares Whilyana Teixeira Dias , Silva Marcos Antônio Barbosa da , Valença Marcelo Moraes , Trindade Filho João Onofre , Pacífico Fernando Augusto
Published: May 2022

Introdução: As malformações arteriovenosas cerebrais (MAV) são lesões vasculares do sistema vascular cerebral durante o período de embriogênese. Relato de Caso: Trata-se de um paciente do gênero masculino de 19 anos, diagnosticado e tratado da primeira MAV no esplênio do corpo caloso. Após 1 ano e meio, o mesmo paciente foi diagnosticado com uma segunda MAV no joelho do corpo caloso, recebendo o segundo tratamento adequado. Comentários: Embora a angiografia cerebral seja considerada padrão ouro para avaliar a angioarquitetura da MAV, torna-se indispensável o acompanhamento de sua evolução após o tratamento cirúrgico, radiocirúrgico ou por embolização, para um diagnóstico decisivo e expansivo, principalmente, em casos de micromalformações.
Guía de citados y referencias según la séptima edición del estilo APA
Authors: Espinoza Coila Michael , Espezúa Salmón Boris Gilmar , Casazola Ccama Juan , Casazola León Johnn Adrian , Rojas Bellido Kelly Cindy , Sampén Contreras Rocío Elena
Published: May 2022

La Facultad de Ciencias Jurídicas y Políticas de la Universidad Nacional del Altiplano de Puno, ha hecho un esfuerzo para dotar a los docentes y estudiantes un texto sobre el APA en español, que concierne a las estructuras del citado, referencias, figuras y tablas.
Capoeira Connections: A Memoir in Motion
Authors: Wesolowski Katya
Published: May 2022

Capoeira Connections follows Wesolowski’s journey from novice to instructor while drawing on her decades of research as an anthropologist in Brazil, Angola, Europe, and the United States. In a story of local practice and global flow, Wesolowski offers an intimate portrait of the game and what it means in people’s lives. She reveals camaraderie and conviviality in the capoeira ring as well as tensions and ruptures involving race, gender, and competing claims over how this artful play should be practiced. Capoeira brings people together and yet is never free of histories of struggle, and these too play out in the game’s encounters. In her at once clear-sighted and hopeful analysis, Wesolowski ultimately argues that capoeira offers opportunities for connection, dialogue, and collaboration in a world that is increasingly fractured. In doing so, capoeira can transform lives, create social spheres, and shape mobile futures. Katya Wesolowski is lecturing fellow of cultural anthropology and dance at Duke University. Publication of this work made possible by a Sustaining the Humanities through the American Rescue Plan grant from the National Endowment for the Humanities.
DA PERIFERIA ÀS PERIFERIAS? PELA CRIAÇÃO DE UM NOVO QUADRO ANALÍTICO DOS ESPAÇOS PERIFÉRICOS
Authors: Cerqueira Eugênia Dória Viana
Published: May 2022

Nas últimas décadas, observa-se uma evolução das periferias urbanas, pautada por um processo de complexificação e diversificação socioespacial. Assim, o presente artigo visa discutir o desenvolvimento de um novo quadro analítico na literatura urbana, que ultrapasse a tradicional abordagem binária, focada no antagonismo entre as áreas centrais e as periferias. Realiza-se uma revisão bibliográfica crítica, amparada por exemplos ilustrativos coletados durante trabalho de campo realizado na Região Metropolitana de Belo Horizonte.
Practicing Positive Aesthetics
Authors: Greaves Tom ,   International Association for Environmental Philosophy
Published: May 2022

This paper rethinks positive aesthetics as a group of aesthetic practices rather than a set of doctrines or judgments. The paper begins by setting out a general approach to aesthetic practices based on Pierre Hadot’s notion of philosophical “spiritual exercises.” Three practices of positive aesthetics are then described: focusing the beauty of each thing; envisioning the beauty of everything; and allowing the beauty of all things. The paper warns against possible dangers to which each practice may fall prey, dangers that divert the practice from its perception cultivating and enhancing potential. The paper ends by drawing out key implications of this way of considering positive aesthetics for our understanding of beauty, negativity and artificiality.
Liturgical Abuse?
Authors: Brunk Timothy M. ,   Philosophy Documentation Center
Published: May 2022

I offer examples of what Catholic liturgical law regards as liturgical abuses. I provide examples of practices that are not formal abuses but raise questions of clericalism, noting that clericalism has contributed to the Catholic sex abuse crisis. I discuss (a) recourse to the tabernacle for distribution of Communion at Mass; (b) reserving one chalice at Mass for the exclusive use of the presider; (c) the installation Mass of Archbishop Nelson Pérez of Philadelphia; and (d) a Mass in Buffalo in the wake of the resignation of then-Bishop Richard Malone. The paper concludes with reflections on what it means to offer worship to God that is necessarily imperfect.
Analysis of vibration signature in deep groove ball bearing using finite element method
Authors: Laxmikant Keni , Padmaraj N.H. , Khan Najiullah , Jagadeesha P.E. , Pradeep R. , Chethan K.N.
Published: May 2022

The most common kind of bearing is the rolling element bearing, which is a used mechanical component in rotating equipment that is subjected to heavy loads and rapid rotation. Bearing failure is the main consideration in the failure of rotating hardware. A deformity at any component of the bearing transmits to every single other component, for example, external race, inward race, ball, and retainer of the bearing. The simplest way to think about ball bearing failure examination is to create counterfeit cracks of varying sizes on various components of CATIA V-6 and write down their signatures. For this reason, the vibration investigation procedure which is dependable and precisely recognizing deformity in the bearing components is utilized. Estimation of the amplitude of vibrations is carried out at 5000 RPM, a load of 200 N, and at different deformity sizes, 3 mm and 4 mm on bearing races are carried out. A preparatory vibration investigation of a rolling component is carried out using Ansys R-18.0. Vibration signals for two diverse imperfection sizes have been extricated and a file for correlation of various deformity sizes has been proposed. The impacts of radial load, rotation speed, and starting deformity size on the stress level are studied.
La investigación mixta como modelo interpretativo musical
Authors: García-Cembellín Javier , Gértrudix-Barrio Felipe , Barraca-Mairal Javier
Published: May 2022

Una investigación mixta, que aúne un trabajo performativo y que esté fundamentada en elementos musicológicos, puede permitir una plasmación interpretativa de mayor coherencia. Para ello, se parte de un postulado primario: la interpretación actúa como vehículo de expresión recreativa de los elementos compositivos si está constituida desde el conocimiento y si es fiel y rigurosa con lo escrito en la partitura original. De este modo, se establece que la interpretación no debe ser una ejecución innata, sino que debe partir de un estudio documental de índole compositivo, musicológico e interpretativo; de lo contrario, carecerá de la necesaria veracidad y rigor analítico dado que no proviene de la comprensión y asimilación del texto, de las ideas musicales y del estilo propio e identificativo del compositor. En el presente artículo, se analizan las diversas tendencias de investigación interpretativa, así como de los heterogéneos postulados establecidos por pensadores como Jerrold Levinson, Peter Kivy, John Butt, Richard Taruskin, Paul Thom, Nicholas Cook, John Rink, Annie Yih, Álvaro Zaldívar o Jorge Luis Moltó. En base a estos principios, se expone que un método mixto de investigación, en el que se aúnan los enfoques performativos y los musicológicos, permite alcanzar un equilibrio interpretativo, en el que la creatividad personal del intérprete está plenamente fundamentada y muestra un rigor científico en sus resultados.
Motivación académica para la elección de temas de investigación en estudiantes de danza
Authors: Anaya Figueroa Tania
Published: May 2022

El presente artículo está orientado al análisis de la motivación académica para la elección de temas de investigación en estudiantes de la carrera de danza tradicional en el Perú. Se parte de la teoría de la autodeterminación para conocer los factores que influyen en los intereses de los estudiantes. Es un estudio cualitativo con el método de estudio de casos, con una muestra de estudiantes del último año de estudios de una escuela de arte que se encuentran realizando su investigación con fines de titulación. Los instrumentos utilizados fueron: cuestionario, entrevista semi estructurada y análisis documental. Como resultados se obtuvo que los factores de motivación académica intrínseca vinculados a las experiencias significativas, de la infancia, vínculos sentimental y familiar son los que priman respecto a la motivación académica extrínseca generada por los padres y familiares, así como el grupo de danza, los amigos y el reconocimiento. Asimismo, el mayor porcentaje de las investigaciones están centradas en la región andina, lo que refleja la fuerte identidad cultural de los alumnos con sus raíces familiares y la variedad de danzas que se presentan en esta parte del Perú. Se develó una alta motivación y actitud propositiva hacia la investigación, vista como un complemento de su actividad artística y una vía para profundizar sus conocimientos.
Desarrollo del Aprendizaje Basado en Proyectos con Realidad Aumentada en educación secundaria para mejorar rendimientos en el aula de música
Authors: RODRÍGUEZ LOPEZ MAURICIO
Published: May 2022

Esta investigación ha sido desarrollada de manera interdisciplinar en 1º y 2º de ESO durante el tercer trimestre del curso 2020-2021 en el IES Amor de Dios de Almería (España). Se ha desarrollado un ABP usando Realidad Aumentada como recurso para mejorar los resultados académicos. La metodología de investigación ha sido la de grupo control y grupo experimental, desarrollando el mismo proyecto el grupo control pero sin posibilidad a usar la Realidad Aumentada.

La evolución que ha tenido la realidad aumentada en los últimos años la ha convertido en una herramienta muy asequible que, además de desarrollar capacidades tecnológicas, nos permite incrementar la motivación y mejorar el rendimiento de los estudiantes; mientras que el ABP ha sido ampliamente estudiado como metodología de trabajo cooperativa para el desarrollo de objetivos de aprendizaje.

A través del trabajo cooperativo y el uso de Halo AR ha sido posible incrementar la participación del grupo y los rendimientos académicos en las áreas de Música y Geografía e Historia. La evaluación se ha realizado usando entrevistas ad hoc con preguntas abiertas para reflexionar sobre las posibilidades de la herramienta y rúbricas para evaluar los logros conseguidos y analizar los rendimientos alcanzados.

Se destaca entre las conclusiones que la metodología y las dinámicas didácticas puestas en marcha hicieron que mejorase la convivencia en el aula dentro del grupo experimental, llegando a participar activamente hasta el alumnado generalmente apático y en ocasiones disruptivo. Los resultados que se han obtenido a pequeña escala en el aula de música hacen necesario extrapolar el trabajo a otras áreas, grupos y centros para ampliar la muestra en un futuro y seguir confirmando los beneficios del ABP mediado con RA.
El mash-up como recurso educomunicativo para la concienciación social sobre feminismo
Authors: Fernández Castrillo Carolina
Published: May 2022

El trabajo parte del diseño de una actividad piloto de Flipped Learning basada en el uso del mash-up. A partir del análisis cuantitativo y cualitativo de los resultados recabados se evaluará su potencial eficacia en la promoción de la concienciación social desde las aulas. El planteamiento de dicha propuesta pretende integrar las dinámicas intercreativas que marcan la rutina digital de millennials y centennials para el desarrollo de una metodología de aprendizaje de tipo cooperativo, experiencial y de servicio. En el caso que nos ocupa, se planteó a los estudiantes que indagaran la presencia del feminismo en Internet para la posterior elaboración de un montaje audiovisual original a partir de materiales preexistentes en la red. De este modo, se pretendía desarrollar su competencia creativa como produsuarios, al tiempo que ejercitaban su empatía hacia una realidad concreta con el fin de contribuir a una socialización inclusiva en entornos conectivos. El estudio aporta información de interés sobre la cultura popular digital en relación a la representación actual de la mujer en el imaginario colectivo online y también en lo relativo al modo en que las nuevas generaciones reformulan dichos referentes a través de la lógica apropiacionista presente en las dinámicas socio-comunicativas cotidianas.
teologia política da “sociedade de vigilância"
Authors: Reichel Hanna
Published: May 2022

Este artigo descreve a sociedade de vigilância contemporânea por meio de uma lente teo-política. Referências ao “olho que tudo vê”, “Big Brother” e o “panóptico” conceituam as tecnologias de vigilância por meio da linguagem de onisciência divina ao mesmo tempo que também cristãos começam a rearticular sua doutrina de Deus em termos e imagens de culturas de vigilância. Com a noção de Karl Barth dos “poderes autônomos” (herrenlose Gewalten; lordless powers), o artigo interpreta a emergência de uma sociedade estruturada por tecnologias de vigilância como forma de um “conhecimento humano desenfreado”. Por meio de uma releitura do Salmo 139, o artigo intenta uma demitização da vigilância ao mesmo tempo que requer o desenvolvimento de mais abordagens “demonológicas” da ética política.
Nutrition Analysis of Wood Apple (Limonia acidissima)
Authors: Ulvie Yuliana Noor Setiawati , Kusuma Hapsari Sulistya , Handarsari Erma
Published: May 2022

AbstractWood apple or Limonia acidissima contains fruit acid, vitamins, and minerals. The dry fiber of the fruit contains 15% citric acid, potassium, calcium, and iron salt. The seed and pulp contain fats and protein. The fats consist of palmitic acid, oleic acid, linoleic acid, and linolenic acid, despite palmitoleic and stearic acid traces. β-sitosterol, β-Amirin, lupeol, and stigmasterol are from the unsaponifiable matter of seed oil. It was descriptive research that employed a laboratory experiment approach to determine the composition of total carbohydrate, total protein, total fats, water, ash content, and the crude fiber of wood apple. The research found that every 100 gram of wood apple contains 72.326% water, 2.144% ash content, 0.00985% crude fats, 4.300% protein, 15.115% fiber, and 5.868% carbohydrate. Keywords: wood apple, nutrition content, composition AbstrakApel kayu atau Limonia acidissima mengandung asam buah, vitamin, dan mineral. Serat kering dari buah ini mengandung 15% asam sitrat, kalium, kalsium, dan garam besi. Biji dan daging buahnya mengandung lemak dan protein. Lemaknya terdiri dari asam palmitat, asam oleat, asam linoleat, dan asam linolenat, dengan sedikit kandungan asam palmitoleat dan stearat. β-sitosterol, β-Amirin, lupeol, dan stigmasterol berasal dari bahan yang tidak dapat disaponifikasi dari minyak biji. Penelitian ini adalah penelitian deskriptif dengan pendekatan eksperimen laboratorium untuk mengetahui komposisi karbohidrat total, protein total, lemak total, air, kadar abu, dan serat kasar kayu apel. Hasil penelitian menemukan bahwa setiap 100 gram kayu apel mengandung air 72,326%, kadar abu 2,144%, lemak kasar 0,00985%, protein 4,300%, serat 15,115%, dan karbohidrat 5,868%. Kata kunci:  apel kayu, kandungan gizi, komposisi
Carbohydrate Intake is Associated with Learning Concentration among High School Students in Jember Regency, East Java Province, Indonesia
Authors: Triyanti Triyanti , Kusharisupeni Kusharisupeni
Published: May 2022

This study aims to determine the relationship between learning concentration and several factors and to find themostdominantfactorinthestudentsofSMAN1Jember.Inthisstudy,learningconcentrationwasthedependentvariable,whilebreakfasthabits,nutrientintake(energy,carbohydrates,protein,fat,iron,zinc,vitamin B12, vitamin C), sleep quality, and physical activity were independent variables. This research is aquantitativestudy with cross-sectional design. This study conducted in June 2021 at SMAN 1 Jemberwith atotal of200 respondents who were selected using the quota sampling method. Data were collected throughfilling out online questionnaires. The data obtained were analyzed using univariate, bivariate analysis using chi-square,andmultivariateanalysisusingmultiplelogisticregression.Theresultsshowthat52.5%oftherespondents had a high learning concentration. The results also show that breakfast habits (p=0,016), energyintake(p=0,037),carbohydratesintake(p=0,000),andsleepquality(p=0,020)arerelatedtolearningconcentration among adolescents. The results of multivariate analysis showed that carbohydrate intake was thedominantfactor associatedwithlearningconcentrationinadolescents.
Oct4 differentially regulates chromatin opening and enhancer transcription in pluripotent stem cells
Authors: Xiong Le , Tolen Erik A , Choi Jinmi , Velychko Sergiy , Caizzi Livia , Velychko Taras , Adachi Kenjiro , MacCarthy Caitlin M , Lidschreiber Michael , Cramer Patrick , Schöler Hans R
Published: May 2022

The transcription factor Oct4 is essential for the maintenance and induction of stem cell pluripotency, but its functional roles are not fully understood. Here, we investigate the functions of Oct4 by depleting and subsequently recovering it in mouse embryonic stem cells (ESCs) and conducting a time-resolved multiomics analysis. Oct4 depletion leads to an immediate loss of its binding to enhancers, accompanied by a decrease in mRNA synthesis from its target genes that are part of the transcriptional network that maintains pluripotency. Gradual decrease of Oct4 binding to enhancers does not immediately change the chromatin accessibility but reduces transcription of enhancers. Conversely, partial recovery of Oct4 expression results in a rapid increase in chromatin accessibility, whereas enhancer transcription does not fully recover. These results indicate different concentration-dependent activities of Oct4. Whereas normal ESC levels of Oct4 are required for transcription of pluripotency enhancers, low levels of Oct4 are sufficient to retain chromatin accessibility, likely together with other factors such as Sox2.
Cytosolic aspartate aminotransferase moonlights as a ribosome-binding modulator of Gcn2 activity during oxidative stress
Authors: Crawford Robert A , Ashe Mark P , Hubbard Simon J , Pavitt Graham D
Published: May 2022

Regulation of translation is a fundamental facet of the cellular response to rapidly changing external conditions. Specific RNA-binding proteins (RBPs) co-ordinate the translational regulation of distinct mRNA cohorts during stress. To identify RBPs with previously under-appreciated roles in translational control, we used polysome profiling and mass spectrometry to identify and quantify proteins associated with translating ribosomes in unstressed yeast cells and during oxidative stress and amino acid starvation, which both induce the integrated stress response (ISR). Over 800 proteins were identified across polysome gradient fractions, including ribosomal proteins, translation factors, and many others without previously described translation-related roles, including numerous metabolic enzymes. We identified variations in patterns of PE in both unstressed and stressed cells and identified proteins enriched in heavy polysomes during stress. Genetic screening of polysome-enriched RBPs identified the cytosolic aspartate aminotransferase, Aat2, as a ribosome-associated protein whose deletion conferred growth sensitivity to oxidative stress. Loss of Aat2 caused aberrantly high activation of the ISR via enhanced eIF2α phosphorylation and GCN4 activation. Importantly, non-catalytic AAT2 mutants retained polysome association and did not show heightened stress sensitivity. Aat2 therefore has a separate ribosome-associated translational regulatory or ‘moonlighting’ function that modulates the ISR independent of its aspartate aminotransferase activity.
Unique neural coding of crucial versus irrelevant plant odors in a hawkmoth
Authors: Bisch-Knaden Sonja , Rafter Michelle A , Knaden Markus , Hansson Bill S
Published: May 2022

The sense of smell is pivotal for nocturnal moths to locate feeding and oviposition sites. However, these crucial resources are often rare and their bouquets are intermingled with volatiles emanating from surrounding ‘background’ plants. Here, we asked if the olfactory system of female hawkmoths, Manduca sexta, could differentiate between crucial and background cues. To answer this question, we collected nocturnal headspaces of numerous plants in a natural habitat of M. sexta. We analyzed the chemical composition of these headspaces and used them as stimuli in physiological experiments at the antenna and in the brain. The intense odors of floral nectar sources evoked strong responses in virgin and mated female moths, most likely enabling the localization of profitable flowers at a distance. Bouquets of larval host plants and most background plants, in contrast, were subtle, thus potentially complicating host identification. However, despite being subtle, antennal responses and brain activation patterns evoked by the smell of larval host plants were clearly different from those evoked by other plants. Interestingly, this difference was even more pronounced in the antennal lobe of mated females, revealing a status-dependent tuning of their olfactory system towards oviposition sites. Our study suggests that female moths possess unique neural coding strategies to find not only conspicuous floral cues but also inconspicuous bouquets of larval host plants within a complex olfactory landscape.
Dysphagia Secondary to Esophageal Compression in a Patient with Decompensated Heart Failure
Authors: Park Jintae , Baek Sora , Kim Gowun , Nam Seung-Joo , Cho Byung-Ryul
Published: May 2022

Cardiogenic dysphagia is a rare type of esophageal dysphagia caused by external compression of the esophagus by an enlarged left atrium. Long-term comparisons between the degree of cardiogenic dysphagia and heart failure have not been reported due to its low incidence. We hereby report the case of a 74-year-old woman with valvular heart disease, suspected of having oropharyngeal dysphagia following a recent intracerebral hemorrhage, who performed a swallowing function test. Videofluoroscopic swallowing study (VFSS) revealed a supraglottic penetration, confirming the oropharyngeal dysphagia. Furthermore, post-VFSS chest radiograph revealed esophageal residual barium, suggestive of reduced esophageal food transition secondary to external compression, at the level of the T6 vertebral body. Chest computed tomography showed mid-esophageal compression caused by left atrial enlargement. She had pulmonary edema which was managed with diuretics. Post-VFSS chest radiographs also revealed a direct association between the diameter of the esophageal barium residue and body weight. A reduction in body weight led to the resolution of the barium residue and vice versa. Development of cardiac dysphagia may be one of the signs of acute exacerbation of heart failure.
Una nota sobre el título del intento de habilitación de Edith Stein ¿Potenz und Akt o Akt und Potenz?
Authors:   PONTIFICIA FACOLTÀ TEOLOGICA TERESIANUM, ROMA, Betschart Christof
Published: May 2022

La contribución estudia la cuestión del título del escrito de Edith Stein Potenz und Akt, que en la traducción española fue cambiado por Acto y potencia. En primer lugar se clasifican los argumentos en la Introducción de la traducción española en cuanto fundados, pero no suficientes para cambiar el título. Luego se exponen dos contrargumentos para mantener el título alemán Potenz und Akt: primero, el hecho de que ya en 1933 fue publicado un libro conocido por Stein de Lorenz Fuetscher con el título Akt und Potenz, lo que excluyó un título idéntico debido a la protección de título. Segundo, el hecho de que Stein durante la redacción cambió el título de su obra principal desde Ser eterno (!) y finito en Ser finito y eterno, por lo cual se aclara su intención filosófica de partir del ser finito-potencial para ascender luego al eterno-actual.
Serositis as a Presenting Feature of Dengue Fever in a Young Female: Forecast of Upcoming Dengue Shock Syndrome
Authors: Kabra Ruchita , Talwar Dhruv , Kumar Sunil , Acharya Sourya , Jaiswal Praraj
Published: May 2022

Dengue fever is a prominent challenge in the developing countries throughout the world, with dengue shock syndrome as a leading cause of morbidity and mortality during the seasonal dengue epidemics. Most common presenting features of dengue fever are high grade fever with chills, headache, rash, nausea and vomiting. With the increasing challenges of treating dengue shock syndrome to prevent mortality in the young, it is important to determine factors which can be used to predict dengue shock syndrome. This report showcases a case of 20-year-old young female who presented with the chief complaint of pedal oedema, pain in abdomen along with breathlessness. Upon investigations it was found to be a of dengue fever with pleural effusion and ascites. The patient later developed dengue shock syndrome, which was managed successfully with the help of intravenous fluids, inotropic support and platelet transfusion. Hence, this case report highlights the importance of detection of serositis in the form of ascites, pleural effusion and pedal oedema in dengue fever as a tell-tale sign of upcoming dengue shock syndrome and the pathophysiology behind it.
«РЕЗНЯ, ГРАБЕЖИ И ПОДЖОГИ»: ФУНКЦИЯ ОПИСАНИЙ ВОЙНЫ В ТЕКСТЕ ХРОНИКИ РЕГИНОНА ПРЮМСКОГО, "Средние века"
Authors: Софронов О.В.
Published: May 2022

Данная статья посвящена изучению функции, которую выполняют описания войны в Хронике Регинона Прюмского. По сравнению с другими конфликтами Регинон уделяет особенно много внимания противостоянию франков и бретонцев с норманнами. Рассказывая о неудачах франков, Регинон отмечает их разобщенность, неспособность объединиться для отпора внешней угрозе, в отличие от бретонцев. Более того, некоторые текстуальные клише, используемые применительно к норманнам (например, указания на их жестокость), переносятся на отдельных предводителей франков, таких как Цвентибальд и Адальберт Бабенберг, что уподобляет их норманнам-язычникам.
«RES PUBLICA CHRISTIANA»: ПОЛИДОР ВЕРГИЛИЙ ОБ «ИЗОБРЕТЕНИИ» ЦЕРКОВНОЙ ИЕРАРХИИ И АДМИНИСТРАТИВНОГО АППАРАТА ПАПСКОЙ КУРИИ, "Средние века"
Authors: Галкова Д.А.
Published: May 2022

Статья посвящена осмыслению истории институализации римско-католической церкви в трактате Полидора Вергилия «Об изобретателях вещей». В своей работе Полидор обратился к изучению истоков христианской религии и, в частности, затронул проблему становления церковно-административного аппарата. Он уделил особое внимание положению Римской кафедры в системе международных отношений, проследил становление иерархии священства, подчеркнул значимость Вселенских соборов, изучил историю происхождения коллегии кардиналов, выборности римского понтифика, куриальных нотариев, индульгенций и налоговой политики папской канцелярии. На примере этих проблемных вопросов в работе Полидора прослеживается попытка использовать принцип историзма для истолкования и преодоления внутрицерковного конфликта.
ПЕРСПЕКТИВЫ ОСВОЕНИЯ ГЕОТЕРМАЛЬНЫХ РЕСУРСОВ СЕВЕРО-КАВКАЗСКОГО РЕГИОНА, "Энергия: экономика, техника, экология"
Authors: Алхасов А.Б.
Published: May 2022

Впоследние годы в мире успешно развивается возобновляемая энергетика, что обусловлено сокращением запасов, ростом стоимости традиционных энергетических ресурсов и экологическими последствиями их использования. Одним из перспективных видов возобновляемой энергии является геотермальная технология, которая успешно конкурирует с другими способами получения энергии.
Effects of Biochar on Yield of Chilli, and Soil Chemical Properties
Authors: Wangmo Tshering , Dorji Sonam , Tobgay Tshering , Pelden Tshering
Published: May 2022

Aims: To examine the effects of different doses of biocharon the yield of chili and soil chemical properties under the Samtenling condition which represents the wet-subtropical agro-climatic zone of Bhutan.

Study Design: Randomized Complete Block Design (RCBD) was used for the study with three replications and five treatments.

Place and Duration of Study: Agriculture Research and Development Centre (ARDC), Samtenling, Sarpang district located in southern Bhutan, between October 2020 and May 2021.

Methodology: Composite soil samples were collected before and after biochar addition and their chemical properties were analyzed at Soil and Plant Analytical Laboratory (SPAL), National Soil Services Centre, Thimphu. One hybrid variety (sv2319HA) of chili was used in all the treatments with five different biochar doses (No biochar addition, biochar addition @ 0.8 t acre-1, 1.6 t acre-1, 3.2 t acre-1, and 4.9 t acre-1).  Growth and yield data of chili were collected and analyzed using the multivariate analysis of variance (MANOVA) at P = .05using R studio team (2021), version 1.4.1103.

Results: The yield of chilli significantly differed (P = .03) under different doses of biochar but variations in growth were insignificant except the number of branches (P = .03). Overall, the yield of chili increased from 0.3 t acre-1 to 0.9 t acre-1 with an increase in biochar rates from 0.8 t acre-1 to 3.2 t acre-1. Biochar addition of 3.2 t acre-1 significantly increased the yield of chili (0.95 t acre-1) as compared to control (0.346 t acre-1). Soil pH, % nitrogen, available P (mg kg-1), available K (mg kg-1), CEC, % BS, and % organic matter increased with increasing quantities of rice husk biochar.

Conclusion: The different doses of biochar addition to the soil had a significantly positive impact on the yield of chili as it also improved the soil’s chemical properties. The addition of 3.2 t acre-1of biochar may be recommended as per the study since the maximum yield of chilli was recorded in soil treated with biochar @3.2t acre-1.
Outcomes-based Education Assessment Practices of UEP Collegiate Faculty Members: Basis for a Training Design
Authors: Adalla Mary June T. , Espinar Mae Joy T. , Ballado Ronato S.
Published: May 2022

It has been a lament of many educators that despite the mandate of the CHED, HEIs have not yet maximally embraced Outcomes-based Assessment (OBA). Educators are still experiencing confusion on the real OBA, hence, the difficulty in shifting from the traditional way of assessment to the real outcomes-based assessment. A descriptive research design was conducted to determine the assessment approaches utilized by UEP faculty members in terms of assessment for learning, assessment of learning, and assessment as learning; found out the perspectives of the respondents on the OBE framework; found out the different assessment tools used by the respondents; and identified the problems/concerns regarding assessment met by the respondents, data of which were used as inputs in the design of a training to enhance faculty members’ assessment practices. The study utilized four-part survey instrument and employed means and percentages to analyze the data. The faculty members “very much practiced” assessment of learning and assessment for learning while they “much practice” assessment as learning. Majority of the respondents had correct perspectives in majority of the items on OBE. However, they had misconceptions on outcomes-based assessment as a norm-referenced kind of testing and that grading is done in every step of the way of the OBE curriculum. On the assessment tools, majority of the faculty members “always” practice the use of teacher-made tests, “often” use some performance based assessment while many alternative assessment format are seldom used. The specific problems encountered by the faculty members were categorized into three: limited facilities and materials, lack of knowledge on OBE and OBA, and, difficulty in the teaching-learning process. Problems met in implementing the Outcomes-based Education framework center on three areas: lack of basic knowledge of OBE and OBA, lack of facilities, and difficulty in the teaching-learning process. Based on the findings of the study, the researchers came up with a training design which will address the concerns of the respondents on assessment in the Outcomes-based Education Framework.
Phyllanthus amarus Aqueous Extract as Antidote to Alcoholic Liver Injury
Authors: Ajani Rotimi Sunday , Alabi Olanike Mutiyat
Published: May 2022

Objective: In most human communities, the consumption of alcoholic beverages is unregulated with negative impact on health. The liver is one of the major organs that bear the brunt of regular and or heavy consumption of alcohol. This study set out to elucidate the modulation of alcohol induced liver injury in wistar rat by aqueous extract of Phyllanthus amarus plant.

Methodology: Five groups of six animals each were used for the study. Group CN was the control. The alcohol only group (ALC) had 1ml / 100g body weight (b.w) of 43% ethanol. The Extract only group (EXT) had 200mg/ Kg b.w of P.amarus aqueous extract.  The Low Extract plus Alcohol group (LEA) had concomitant administration of 1ml/100g b. w of 43% ethanol with 200 mg/ Kg of the extract. The High Extract plus Alcohol group (HEA) had concomitant administration of 1ml/100g b. w of 43% ethanol and the extract at 400 mg/ Kg. The alcohol and extract were administered once daily for fourteen days. Thereafter, blood samples were collected for biochemical analyses, the animals sacrificed and livers harvested for histopathological analyses.

Results: Group HEA had the highest mean body weight. The mean liver weight of group EXT was significantly higher than those of other groups. Both the total protein and its globulin fraction of the ALC group were significantly lower than those of others. The liver enzymes (Alanine and Aspartate transaminases) levels were significantly low in the ALC group. However, those of the LEA and HEA groups were comparable with the EXT group. The glutathione peroxidase and superoxide dismutase activities of the LEA and HEA groups were significantly higher than that of ALC. Lipid peroxidation was most severe in the ALC group as evidenced by the significantly high malondialdehyde level. Histopathological sections of the liver revealed preserved hepatic architecture with pronounced steatosis in the ALC group.

Conclusion: Aqueous extract of Phyllanthus amarus considerably reduced the severity of alcohol induced liver injury.
Impact of Nitrogen and Iron on Growth and Yield Attributes of Chickpea (Cicer arietinum L.)
Authors: Reddy Mandra Vamsidhar , Singh Rajesh , Thakur Indu
Published: May 2022

Background: Chickpea is leguminous crop, which offers a good nutrition to people across the world. Chickpea ranks second after soybean as the common leguminous crop that people grow and consume across the world. Therefore, its study is significant because chickpea has nutritional and economic importance in the world.

Objectives: Effect of Nitrogen and Iron on growth and yield of Chickpea.

Methods: With the goal of studying the effect of Nitrogen and Iron on growth and yield of chickpea (Cicer arietinum L.) var RVG-202 under a Randomized block design with 9 treatments which are replicated thrice. The experimental results revealed that of 25 kg/ha Nitrogen +7.5kg /ha Iron recorded maximum plant height (48.8 cm), number of nodules per plant (23.0), plant dry weight (55.7g/plant), number of pods per plant (61.2), number of seeds per pod (3.5), Seed yield (1919.1 kg/ha), Haulm Yield (3186.6 kg/ha).

Conclusion: 25 kg/ha Nitrogen and 7.5kg /ha Iron determined to be the most beneficial to farmers, resulting in plant height (48.8 cm), dry weight (55.7g/plant), nodules per plant (23.0), number of pods per plant (61.2), number of seeds per pod (3.5), seed yield (1919.1kg/ha) and Haulm yield (3186.6 kg/ha).
Effect of Mulching and Sulphur on Growth and Yield of Yellow Mustard (Sinapis alba)
Authors: Babu C. Sharath , Singh Shikha , Kumar Sam Praveen , Shireesha .
Published: May 2022

This study was conducted at Crop Research Farm, Department of Agronomy, Naini Agricultural Institute, SHUATS, Prayagraj (U.P) in Rabi, 2021 to study the Effect of Mulching and Sulphur on Growth and Yield of Yellow Mustard (Sinapis alba). It was consisting of combination of three types of Mulching No mulch, Paddy straw and Poly sheet mulch and three Sulphur levels (20kg S/ha, 40 kg S/ha and 60 kg S/ha). The study was laid out in Randomized Block Design with nine treatments each replicated thrice. The experimental results revealed that the growth parameters and yield parameters such as plant height (145.94 cm), dry weight (34.30 g), number of branches/plant (11.58), number of seeds/siliquae (37.41) and test weight (3.08 g) at harvest, significantly recorded in treatment T9 with the application of Poly sheet mulch+60 kg S/ha. Moreover, seed yield (1.82 t/ha), stover yield (3.94 t/ha), gross return (95,762.64 INR/ha), net return (52,487.44 INR/ha) and B:C ratio (2.21) were also recorded significantly higher in the treatment which is Poly sheet mulch + Sulphur 60 kg/ha among all treatments.
Determining the Impact of Age, Sex and Location in the Spread of Tuberculosis Infection among Patients, in Bayelsa State Nigeria, using Molecular Technique
Authors: Silas Goodluck , Enoch Amala, Smart , Ollor Amba, Ollor , Agi Vivian Nkemkanma
Published: May 2022

Introduction: Tuberculosis is a disease condition caused by Mycobacterium tuberculosis. Several predisposing factors such as Age, Sex and overcrowding may have affected the prevalence of tuberculosis in various locations including Bayelsa State and other parts of the world.

Aim: The aim of this study is to know if Age, Sex and Location determines tuberculosis rate of infection, using molecular technique to isolate Mycobacterium tuberculosis among tuberculosis patients in Bayelsa State, Nigeria.

Methodology: We analyzed a total of 102 sputum samples, which were collected from each of the participants. GeneXpert molecular method was used to identify Mycobacterium tuberculosis and Rifampicin resistant cases. The data and results obtained are statistically analyzed with Statistical Package for Social Science (SPSS) version 21.

Result: Out of the 102 sputum samples screened, 91(89.2%) were confirmed to have tuberculosis, Tuberculosis among male and female were 54(52.9%) and 37(36.3%) respectively, while rifampicin resistance among male and female were 3(2.9%) and 5(4.9%) respectively. Tuberculosis infection among male and female were not statistically significant (p = .75). The age intervals are 11-20, 21-31, 31-40, 41-50, 51-60, 61-70 and 71-80. 31-40 years had the highest tuberculosis prevalence of 30(29.4). The various locations were Brass, Ekeremor, Kolokuma/Opokuma, Nembe, Ogbia, Southern Ijaw and Sagbama Local Governmemt Areas. People residing in Yenagoa local Government had more positive case of both rifampicin resistant 5(4.9%) and non-rifampicin resistant tuberculosis infection.

Conclusion: Tuberculosis infection is more predominant among male in Bayelsa State than female but rifampicin resistance species are more predominant among females. The age group interval of 40-41 had the highest prevalence of tuberculosis infection while the highest location of tuberculosis infection is Yenagoa.
Fedratinib: A Review of Its Pharmacology and Clinical Use
Authors: Ashisha P. , Archana M. , Palathingal Mariya , Damodharan K. Athulya , Nuaman . , Marathakam Akash
Published: May 2022

Fedratinib (INREBIC®) is a JAK2-selective inhibitor that has been developed as an oral treatment for myelofibrosis. It was approved for the first time in the United States in August 2019 to treat adult patients with intermediate-2 or high-risk primary or secondary (post-polycythaemia vera or post-essential thrombocythemia) myelofibrosis. Fedratinib is an anilinopyrimidine derivative and is metabolized by CYP3A4, CYP2C19 and flavin-containing monooxygenase-3. Fedratinib is mainly excreted in faeces, and the effective half-life is 41 hours. The recommended dosage is 400 mg once daily (with or without food. The dosage should be reduced to 200 mg once daily in patients receiving CYP3A4 inhibitors and in patients with severe renal impairment. Fedratinib's recent approval adds to the few therapeutic option choices available to individuals with MF. The most common adverse events were mild gastrointestinal toxicities. Fedratinib comes with a boxed warning about the risk of serious and potentially deadly encephalopathies, such as Wernicke's.
Republicanismo versus multiculturalismo: diversidade, religião e Estado na França e na Grã-Bretanha
Authors: Amorim Carvalho Tarcísio
Published: May 2022

O presente artigo tem como objetivo discutir as recentes medidas de acomodação religiosa na França e na Grã-Bretanha, principalmente aquelas relacionadas ao porte de símbolos religiosos nos ambientes escolares, à luz da teoria e dos discursos políticos oficiais. Com efeito, enquanto em 2004, uma lei francesa proibiu o uso de símbolos religiosos ostensivos nas escolas públicas baseando-se, sobretudo, no argumento da igualdade republicana, o governo britânico vem legitimando a discriminação positiva em vista de identidades religiosas. Ao lançar mão de conceitos como republicanismo e multiculturalismo, os atores políticos delineiam os limites do religioso no espaço público e buscam traçar diretrizes para a construção de um ideário nacional.
The beginning and the end of SNARE‐induced membrane fusion
Authors: Mion Delphine , Bunel Louis , Heo Paul , Pincet Frédéric
Published: May 2022

Membrane fusion is not a spontaneous process. Physiologically, the formation of coiled‐coil protein complexes, the SNAREpins, bridges the membrane of a vesicle and a target membrane, brings them in close contact, and provides the energy necessary for their fusion. In this review, we utilize results from in vitro experiments and simple physics and chemistry models to dissect the kinetics and energetics of the fusion process from the encounter of the two membranes to the full expansion of a fusion pore. We find three main energy barriers that oppose the fusion process: SNAREpin initiation, fusion pore opening, and expansion. SNAREpin initiation is inherent to the proteins and makes in vitro fusion kinetic experiments rather slow. The kinetics are physiologically accelerated by effectors. The energy barriers that precede pore opening and pore expansion can be overcome by several SNAREpins acting in concert.
Adaptive event‐triggered synchronization control for bilateral teleoperation system subjected to fixed‐time constraint
Authors: Zhao Ying , Liu Peter Xiaoping , Wang Huanqing
Published: May 2022

The time‐constrained positional synchronization control problem for a class of bilateral teleoperation systems is investigated and a novel fixed‐time event‐triggered control scheme is developed. Different from existing methods, the controller is triggered in a nonperiodic manner, which reduces considerably the triggering frequency of control devices. This not only saves communication resource, but also extends the lifespan of system devices because of the reduction of switching times. The control settling time is further considered by introducing a fixed‐time stability theorem. Theoretical analysis as well as a simulation example verifies that the proposed control method can reduce remarkably the amount of control signals transmitted between the master and slave while ensuring that the system output tracking error converges to a small neighborhood close to zero within a fixed‐time frame.
AATOD opposes H.R. 1384 and S. 445
Authors: Knopf Alison
Published: May 2022

Noting that the “facts on the ground have changed” since 2019, when the Mainstreaming Addiction Treatment (MAT) Act was first introduced, the American Association for the Treatment of Opioid Dependence (AATOD) said it's time to reconsider this proposal. AATOD has never been in favor of the MAT Act, but three changes have made the proposal even more problematic (see AATOD, supporter of the MATE Act, fact‐checks the MAT Act, ADAW Feb. 24, 2020; https://onlinelibrary.wiley.com/doi/10.1002/adaw.32636).