bluuebunny/crossref_metadata_2025 huggingface dataset:
Research activity of students in the study of the section «Stereometry»
Authors:   Khoja Akhmet Yassawi International Kazakh-Turkish University, Alikhanova B. , Utebaeva G. ,   Khoja Akhmet Yassawi International Kazakh-Turkish University
Published: April 2023

The article discusses the importance of developing the experience of students' research activities in the study of geometry, and in particular the section «Stereometry». The relevance of the research lies in the development of pedagogical practice of mathematics teachers for the formation of research skills of high school students, which better determine the search ability, critical thinking through reflection, comprehension when solving problems. In the process of conducting a study to develop the student's thinking ability, his own pedagogical teaching practice was analyzed. In geometry lessons, teaching methods were used to form students' research abilities in solving problems: the ability to work with text, write a short note, apply theoretical material, work with additional lines. In order to develop theoretical material, determine the research activities of students, the advanced works of scientists and teachers, and research practice by the method of pedagogical analysis were studied. As a result of observation and research of pedagogical practice of teaching, it was noticed that children began to be more interested in geometry, to think spatially, a meaningful understanding of the subject appeared. Students' research activities were organized through mathematical projects. When working with the project, students were active in studying new topics, self-esteem, motivation for development, skills for search work, the ability to explore. When observing the process of learning geometry, it was found that the development of research abilities in solving problems increased the percentage of learning quality. Therefore, it is necessary for a mathematics teacher to introduce more stereometric tasks into his teaching practice, which are designed to form critical thinking and represent spatial thinking. To form motivation, self-esteem of the student, mathematics teachers can organize work on projects.
Streamlines based methodology for determining the acidity balance of solutions of technological blocks developed by in-situ leaching
Authors:   Satbayev University, Kurmanseiit M. B. ,   Al-Farabi Kazakh National University, Uzbekaliyev K. Sh. ,   Al-Farabi Kazakh National University, Tungatarova M. S. ,   Satbayev University; Al-Farabi Kazakh National University, Alibayeva K. A. , Kaltayev A. ,   Satbayev University; Al-Farabi Kazakh National University
Published: April 2023

The in-situ leaching is a method of developing low-concentration ore deposits occurring in permeable rocks by pumping a leaching solution into the reservoir through injection wells, which dissolve the mineral in situ and pumping the productive solution to the surface through pumping wells. During development, the deposit is divided into technological blocks; developments of each block could be independent from others. To improve the environmental friendliness of work and prevent the spreading of solutions beyond the boundaries of the block, a balance of solutions is observed, i.e. the volumes of injected leaching and pumped out productive solution should be equal. In this connection, the question arises of calculating flow rates at injection wells in adjacent blocks. Currently, the distribution of flow rates of injection wells in adjacent technological blocks is calculated by averaging the extraction wells interacting with a given well. However, the accuracy of this calculation is quite low, since it does not take into account both the reservoir properties and the distances between wells. In this connection, in this paper, it is proposed to calculate well flow rates based on modeling, based on the fundamental laws using streamlines. Thus, the proposed technique makes it possible to take into account the direction of the flow of the solution and the filtration properties of the rock.
Pelatihan Literasi pada Masyarakat Desa Renah Jelmu: Kampung Literasi Anak Negeri
Authors: Oktavia Diana , Elbas Cenby Rosella , Irwansyah KMS Ade , Sartika Rahayu , Chania Eldini
Published: April 2023

Pelatihan Literasi pada masyarakat desa Renah Jelmu dilaksanakan untuk membantu masyarakat dalam meningkatkan kemampuan literasi. Program ini dilaksanakan dalam bentuk pengajaran membaca dan berhitung bagi anak-anak dan pemuda setempat. Kegiatan pengajaran dilaksanakan sekali dalam setiap minggu dengan menggunakan media-media menarik. Selain itu, program ini juga dikemas dalam bentuk sosialisasi kepada orang tua di desa Renah Jelmu mengenai pentingnya pendidikan, pernikahan dini serta pelatihan pembuatan kreativitas seperti pembuatan keripik tebu. Guna mendukung program peningkatan literasi ini, tim pengabdian juga membuat pojok baca yang dapat diakses oleh semua warga desa Renah Jelmu. Kegiatan ini diikuti dengan antusias oleh warga sekitar.
Penyalahgunaan Keadaan (Misbruik Van Omstandigheden) yang Mengakibatkan Batalnya Perjanjian (Studi Kasus Putusan Nomor 234/Pdt.G/2020/Pn.Mtr)
Authors: Salam M. Nur , Salim HS Salim , Munandar Aris
Published: April 2023

Penelitian ini bertujuan untuk untuk mengetahui konsep dan unsur penyalahgunaan keadaan dalam New BW Belanda dan common law system dan untuk mengetahui penerapan dan dasar pertimbangan hakim memutuskan perkara Putusan Nomor : 234/Pdt.G/2020/PN.Mtr tentang penyalahgunaan keadaan (misbruik van omstandigheden) . Penelitian ini merupakan jenis penelitian hukum normatif, dengan menggunakan pendekatan Undang-Undang (Statute Approach), pendekatan konseptual (conceptual approach), dan pendekatan kasus (case approach). Hasil penelitian ini menunjukkan bahwa: 1) Meijers, sebagai tokoh dalam penyusunan Nieuw Burgerlijk Wetboek (NBW) menyatakan bahwa rumusan tentang penyalahgunaan keadaan tersebut didasarkan pada doktrin undue influence dalam hukum Inggris. Doktrin penyalahgunaan keadaan tersebut kemudian dicantumkan dalam Buku III Pasal 44 ayat (1) NBW, yang menegaskan bahwa, suatu perjanjian dapat dibatalkan oleh para pihak jika terdapat ancaman (bedreigeng), tipuan (bedrog), termasuk penyalahgunaan keadaan (misbruik van omstandigheden) dalam pembentukannya. 2) Majelis Hakim dalam pertimbangannya menyatakan  “secara spesifik perbuatan Tergugat I dan Tergugat II menurut hukum adalah penyalahgunaan keadaan, sehingga Majelis Hakim berdasarkan ex a quo et bono, menyatakan perbuatan Tergugat I dan Tergugat II sebagai perbuatan penyalahgunaan keadaan.” keputusan Majelis Hakim merujuk pada Putusan Mahkamah Agung Republik Indonesia Nomor 3406 K/Pdt/2019, tanggal 16 Desember 2019 yang telah membatalkan Akta jual beli atas tanah dengan alasan penyalahgunaan keadaan (misbruik van omstandigheden). Hal ini sesuai dengan teori Vandunne tentang unsur ekonomi lemah yang terdapat dalam perjanjian.
Kebijakan Legislasi “Cyber Sex” Pada Forum Anonymous Chatbot Telegram Menurut Undang-Undang ITE
Authors: Hidayat BR , Ufran Ufran , Rodliyah Rodliyah
Published: April 2023

Penelitian ini bertujuan untuk mengetahui Kebijakan Legilasi Tindakan Cyber Sex Pada Forum Anonymous Chat Bot melalui media aplikasi telegram menurut Undang-Undang ITE serta penanggulangan Cyber Sex pada forum Anonymous Chat bot telegram. Dengan menggunakan metode penelitian hukum normatif yang mengkaji bagaimana sebenarnya kebijakan legislasi yang dapat di tempuh guna memberikan dan mengetahui tindakan pidana dalam forum Anonymous Chat bot telegram. Hasil penelitian ini menunjukan bahwa Undang-Undang No. 11 Tahun 2008 Jo Undang-Undang No.19 Tahun 2016 dari rumusan Pasal 27 ayat (1) Undang-Undang Nomor 19 Tahun 2016 tentang Informasi dan Transaksi Elektronik, tidak akan menimbulkan permasalahan, karena tiap unsur yang perlu dalam sebuah rumusan tindak pidana sudah terpenuhi. Akan tetapi jika dicermati lagi pada delik pembuatan masih membutuhkan KHUP dalam penegakannya yang harus dipahami UU ITE tidak bisa secara lex spesialis dalam mengatur dan memberikan legitimasi yang tegas terhadap para pelaku Cyber Sex. Penanggulangan Cyber Sex harus dilakukan tidak hanya kebijakan penal  semata oleh karena itu dalam menanggulangi  Cyber Sex membutuhkan penanggulangan secara integral seperti yang terdapat dalam teori situation crime prevention dengan menghilangkan kesempatan bagi pelaku untuk melakukan perbuatannya.
Penguatan Hak Milik Atas Tanah Berdasarkan Putusan Pengadilan (Analisis Putusan Nomor 42/Pdt.G/2018/PN Mataram)
Authors: Jaelani Rian Topan , Ufran Ufran
Published: April 2023

Penelitian ini bertujuan untuk mengetahui dasar pertimbangan hakim dalam mengeluarkan putusan Pengadilan Negeri Mataram tentang penguatan hak milik atas tanah berdasarkan putusan pengadilan nomor 42/PDT.G/2018/Pengadilan Negeri Mataram. Metode penelitian yang digunakan adalah penelitian hukum normatif, karena pembahasan penelitian ini untuk mengetahui dasar pertimbangan hakim dalam mengeluarkan putusan didalam persidangan. Simpulan dari penelitian ini adalah penguatan hak milik atas tanah berdasarkan putusan pengadilan sesuai dengan hasil dalam persidangan.
Taman Belajar: Peningkatan Literasi dan Numerasi Melalui Bahasa Inggris, Matematika dan Keagamaan
Authors: Ramadhan Abid , Sari Puspa
Published: April 2023

The learning garden is implemented as an additional learning facility for school children in the Tarobok village. This program aims to mobilize children to carry out positive activities and repeat the lessons they previously received at school. activities carried out include general learning such as reading, counting and memorizing. Learning English and religious education is also carried out in the learning park. The techniques used are quizzes, presentations, focus group discussions, and singing. The results of this activity really helped the children to increase their enthusiasm for learning, especially in the aspects of literacy and numeracy. Abstrak: Taman belajar dilaksanakan sebagai sarana pembelajaran tambahan bagi anak-anak sekolah di desa tarobok. Program ini bertujuan untuk memobilisasi anak-anak agar melakukan aktivitas positif dan mengulangi pembelajaran yang sebelumnya mereka dapatkan di sekolah. aktivitas yang dilakukan antara lain pembelajaran umum seperti membaca, menghitung dan menghapal. Pembelajaran lain seperti Bahasa inggris dan Pendidikan agama juga di lakukan di taman belajar. Teknik yang dilakukan yakni kuis, presentasi, focus group discussion, dan bernyanyi. Hasil kegiatan ini sangat membantu anak-anak meningkatkan semangat belajar khususnya dalam aspek literasi dan numerasi.
Training on Separation of Organic and Inorganic Waste in Blimbing Village, Paciran Lamongan District
Authors: Solekha Rofiatun , Savitri Nynda Ayu Nadira , Rachmadani Karin Alifia , Musyarofah Badriatul , Ramadani Aisyah Hadi
Published: April 2023

Waste problems are becoming increasingly complex due to the lack of waste processing facilities, low public knowledge about waste management, and the rapid population growth in Paciran District, Lamongan Regency. This activity is carried out with the aim of utilizing it by sorting waste and processing it so that it can produce products. Trash that is scattered on the road is generally due to the low awareness of the surrounding community to dispose of waste in its place. Community service activities are carried out by socialization and training. The socialization carried out is to provide counseling to the community about how to dispose of waste and sorting household waste. Training was conducted for TPS3R officers on how to sort and use them. Organic waste obtained from food scraps is used as maggot feed, while inorganic waste is sold to collectors so that it can increase people's income in the Blimbing village. Apart from that, this activity also produced a BSF (Black Soldier Fly) installation, which is a place for maggot cultivation. It is hoped that in the future this community service activity can be carried out in a sustainable manner, so that the waste in the Blimbing sub-district can be utilized into something of economic value.
Membangun Sikap Kerja Profesional Karyawan Anara Airport Hotel Tangerang
Authors: Pujianto Surahman , Arilyn Erika Jimena , Suryawan Ian Nurpatria , Soediono Wibisono
Published: April 2023

Community service activities include increasing the speed of community development efforts towards fostering a harmonious and dynamic society that is ready to take chances towards improvement and progress in accordance with socio-cultural values and norms in the life of a developing community in the life of the prevailing society. This training uses an explanatory case study approach to explain various case studies of the professional work attitudes of Anara Airport Hotel employees. The main activities of the training besides presentation and explanation of the material, a simple assessment of the professional work attitude of employees is also carried out, namely the FGD (focus group discussion) method and case studies. Abstrak: Kegiatan pengabdian kepada masyarakat beberapa diantaranya adalah bertambahnya kecepatan upaya pengembangan masyarakat ke arah terbinanya masyarakat yang harmonis serta dinamis yang siap menempuh perubahan-perubahan menuju perbaikan dan kemajuan sesuai dengan nilai-nilai sosial budaya dan norma-norma dalam kehidupan masyarakat berkembang dalam kehidupan masyarakat yang berlaku. Pelatihan ini menggunakan pendekatan studi kasus eksplanatori untuk menjelaskan berbagai studi kasus sikap kerja profesional karyawan Anara Airport Hotel. Aktivitas utama pelatihan selain presentasi dan penjelasan materi, juga dilakukan asesmen sederhana atas sikap kerja professional kerja para karyawan, yakni dengan metode FGD (focus group discussion) dan studi kasus.
Pengolahan Limbah Kotoran Kambing dan Penambahan Agen Hayati Menjadi Pupuk Kompos di Desa Solokuro, Kabupaten Lamongan
Authors: Setiyowati Putri Ayu Ika , Ramadani Aisyah Hadi
Published: April 2023

Agriculture is an unavoidable human activity, as all people require food to survive. As time passes, more and more chemicals for agricultural production are becoming available to farmers, which will gradually diminish crop yields. Therefore, it is vital to provide counseling and training on producing organic fertilizer using the plentiful goat manure waste in Solokuro Village. This course aims to expand knowledge of how to manufacture compost from goat dung waste as an organic fertilizer on food crops on farms and in yards. Counseling and training techniques were utilized in the implementation of the program. Providing detailed information on the benefits of goat dung waste is one counseling method. As part of the training, the community was provided with information on how to manufacture compost and include biological agents through fermentation procedures packaged as practice and simulation. The results of the compost fertilizer advice and training were quite successful. Participants were very enthusiastic and eager to learn about goat dung waste processing processes that may be utilized to create compost, as they were previously unaware of such methods. In addition, farmers understand the characteristics of soil and the many types of organic fertilizers, as well as the methods for producing and applying them on fields. Abstrak: Pertanian merupakan kegiatan yang tidak bisa dihindari manusia, karena semua manusia perlu makan sebagai keberlanjutan hidupnya. Seiring berjalannya waktu, berbagai bahan kimia untuk produksi pertanian semakin bermunculan dikalangan para petani yang lambat laun akan menurunkan produktifitas hasil panen. Sehingga perlu dilakukan penyuluhan dan pelatihan pembuatan pupuk organik yaitu dengan memanfaatkan limbah kotoran kambing yang keberdaannya melimpah di Desa Solokuro. Pelatihan ini bertujuan untuk meningkatkan pemahaman tentang cara pembuatan pupuk kompos dari limbah kotoran kambing sebagai pupuk organik yang dapat digunakan pada tanaman pangan di lahan pertanian maupun pekarangan. Pelaksanaan program dilaksanakan dengan menggunakan metode penyuluhan dan pelatihan. Penyuluhan dilakukan dengan memberi pengetahuan khusus tentang manfaat limbah kotoran kambing. Sedangkan pelatihan dilakukan dengan memberikan informasi kepada masyarakat tentang cara pembuatan kompos dengan penambahan agensia hayati melalui teknik fermentasi yang dikemas dalam bentuk praktek dan simulasi. Hasil penyuluhan dan pelatihan pembuatan pupuk kompos berjalan dengan sangat baik. Peserta sangat antusias dan tertarik untuk mengetahui semuanya karena selama ini belum tahu tentang teknik pengolahan limbah kotoran kambing yang efektif dan dapat dimanfaatkan untuk pembuatan pupuk kompos. Tidak hanya itu, petani juga memahami karakteristik tanah maupun jenis-jenis pupuk organik sekaligus teknik pembuatan dan pengaplikasiaannya di lahan pertanian.
Pengembangan Model Pembelajaran Motorik Kasar Berbasis Permainan Tradisional untuk Anak Sekolah Dasar Kelas Tinggi di Kecamatan Batulayar
Authors: Al Ghazi Syam’un
Published: April 2023

This study aims to: (1) Develop a traditional game-based gross motor learning model, and (2) Test the suitability of using the developed product in terms of the traditional game-based gross motor learning implementation model. The research and development design consists of seven steps, namely (1) existing product research (literature study and field research), (2) product development planning, (3) 1st internal design test (expert validation), (4) 1st product revision, (5) internal design test 2nd (expert validation), (6) 2nd product revision, (7) final product. Collecting research data using questionnaires and documentation techniques, with research instruments and scoring sheets used by experts in the first and second expert validation stages. Data analysis used qualitative and quantitative descriptive analysis techniques. The result of the research is the development of a traditional game-based gross motoric learning model for high-grade elementary school children fulfilling the "appropriate" category. as an alternative to gross motor learning for high school elementary school children in the Batulayar sub-district.
Integrasi Kewenangan KPPU dengan Penyidik Kepolisian dalam Penegakan Hukum Persaingan Usaha Pasca Putusan KPPU
Authors: Sajidin Muhammad , Asikin Zainal , Muhaimin Muhaimin
Published: April 2023

Penelitian ini bertujuan untuk menganalisis dan mengidentifikasi terkait upaya integrasi kewenangan antara KPPU dengan Kepolisian RI dalam penegakan hukum persaingan usaha Pasca Putusan oleh KPPU. Penelitian ini merupakan jenis penelitian hukum normatif, dengan menggunakan pendekatan perundang-undang (statute approach), pendekatan konpseptual (conceptual approach), dan pendekatan kasus (case approach). Hasil dari penelitian ini menunjukkan bahwa dalam menjalankan tugasnya, KPPU dapat bekerjasama dengan Penyidik dalam hal ini Polri. Hubungan yang dibangun dengan pihak Kepolisian dalam penegakkan hukum di bidang persaingan usaha ini tentunya sangat terbatas, hal ini karena Undang-Undang Nomor 5 Tahun 1999 tentang Larangan Praktek Monopoli dan Persaingan Usaha Tidak Sehat ini telah mengamanatkan kepada KPPU sebagai lembaga yang mempunyai kewenangan mutlak (utama) untuk melakukan penegakan hukum di bidang larangan praktek monopoli dan persaingan usaha tidak sehat.
ANTAGONIST TEST OF TRICHODERMA HARZIANUM AGAINST GANODERMA BONINENSE CAUSES OF OIL PALM BASAL STEM ROT DISEASE
Authors: Kusmawanto Arif , Himawan Achmad , Kristalisasi Elizabeth Nanik
Published: April 2023

This study aims to determine the type of Trichoderma fungus that can inhibit the growth of G. boninense and determine the percentage of inhibition of Trichoderma on the growth and development of G. boninense. This research was conducted at the Central Laboratory of the STIPER Agricultural Institute Yogyakarta in February-March 2022. G. boninense samples were taken from three different plantation locations belonging to residents of Aek Paing Atas Village and Aek Paing Bawah Satu Village, Kec. Rantau Utara, Kab. Labuhan Batu and Aek Janji Village, Kec. Rantau Selatan, Kab. Labuhan Batu, North Sumatra. Trichoderma samples were taken from Naga Soppah Village, Naga Harjo Village and Bahung Kahean Village. The research method used is descriptive by identifying antagonistic (Trichoderma) and pathogenic (G. boninense) fungi. Data on the percentage of inhibition of fungi were analyzed quantitatively. Fungi macroscopic and microscopic characterizations were analyzed qualitatively. The results showed that the Trichoderma fungus that could inhibit the growth of G. boninense was T. harzianum. The highest percentage of inhibition power of T. harzianum (Naga Soppah Village) against G. boninense (Aek Paing Bawah Satu village) was 30%.
Exploring the Acute Toxicity of Ammonium Salt Using Water Flea as Indicator Organisms
Authors: JIN Shubo , YANG Zhiguang , ZHANG Junzheng , YANG Jingye , CHEN Shuo , HAO Qingyuan , HE Xiaoxiao , WANG Chenxi , HUO Yu , GU Shiyuan , ZHAO Xiuxiu , ZHANG Wenqi
Published: April 2023

Ammonium sulfate and ammonium chloride are widely used in daily production and life. They can be used as nitrogen fertilizer in agricultural fields and as raw materials for other chemical products in factories. Under the action of precipitation and other factors, these compounds can have a certain impact on water ecology when they enter natural water bodies. In the paper, the acute toxicity of ammonium sulfate and ammonium chloride was investigated using water fleas as indicator organisms. According to GB/T 16125- 2012 test method for acute toxicity of water flea, the 24h-LC50 values of the acute toxicity of ammonium sulfate and ammonium chloride to water flea were 469. 894mg/L and 546. 720mg/L respectively, which were classified as slightly toxic according to the toxicity class.
Experimental Study on the Effect of Ultrafine Mineral Admixtures on the Mechanical Properties of Cement Mortar
Authors: DING Xiangqun , LI Tingyu , YANG Baoxin
Published: April 2023

Objective: The effect of ultrafine mineral admixtures on the mechanical properties of grouting mortar was studied. Methods: In this paper, the compressive strength and flexural strength of the mortar with different contents of ultrafine mineral admixture replacing cement were tested respectively, and the heat of hydration was tested. XRD and SEM were used to analyze the changes in the microstructure characteristics after the addition of ultrafine mineral admixture. Results: after the addition of 5% ultrafine mineral admixture, the fluidity of cement slurry decreased by 25. 3%, and the fluidity gradually decreased with the gradual increase of ultrafine mineral admixture. With the addition of superfine mineral addition, The compressive strength increased steadily and gradually decreased thereafter, while the content of superfine mineral added was 20%, the strength of rubber sand reached the maximum value at 28 days, which increased by 23. 76% compared with the test block without admixture. The flexural strength of 3d and 7d of rubber sand was weakened by the incorporation of ultrafine mineral admixture, and the flexural strength of 28d increased slowly with the incorporation of ultrafine admixture, and the flexural strength value reached the maximum when the dosage was 25%. The heat of hydration and microstructure analysis showed that the sand system produced more hydrated calcium silicate gel filling into the structure of the sand after the addition of ultrafine mineral admixture. Conclusion: a certain amount of ultrafine mineral admixture has remarkable influence on the compression strength of rubber sand, and the flexural strength of 3d and 7d is weakened, and increases the flexural strength of 28d.
Meta-code Symbols Duplication in the Cultural Genes
Authors: JI Hong
Published: April 2023

In the educational process, cultural genes duplication and scientific knowledge learning are two main lines that go hand in hand. Scientific knowledge needs to be learned in verification, and cultural genes need to be copied. Compared with the chromosomes of biological genes and the double-helix structure of DNA, Chinese cultural genes have six pairs of “chromosomes”, of which five pairs are autosomes and one pair is sex chromosomes. The five pairs of autosomal chromosomes are composed of five tones, namely Gong, Shang, Jiao, Zheng and Yu. The sounds are arranged by four tonal symbols, the musical tones are arranged by twelve laws, and the sex chromosomes are arranged by the yin and yang symbols. “Book of Songs” and “Book of Changes” are the cultural gene symbols that Chinese people should try to duplicate most. The Book of Songs is a symbol of phonetic gene, and the Book of Changes is a symbol of text gene. The former reflects on the past, the latter plans for the future. The two types of symbols in the “Book of Songs” and the “Book of Changes” separate the past and the future, so that we can live in “Dasein” calmly without being constricted, as if we have God􀆳s help. Having “Book of Songs” and “Book of Changes” endorsed for us is like inheriting a rich heritage and having a strong spiritual backing to resist the violation of “false and ugly” symbols. Zhu Zaiyu, a great musician in the Ming Dynasty, believed that “Daya” was a palace tone, “Xiaoya” was a levy tone, and “Guofeng” was a corner tone. Sima Qian said, “Orthodox people all start with sound: if sound is right, behavior. is right. ” Voice comes from the mind. Only when the mind is correct can behaviors be correct. Correct education begins with voice.
The Existing Problems and Solutions of Life Safety Education for Contemporary Rural Teenagers
Authors: WU Ning , MENG Xian
Published: April 2023

The problems existing in the life safety education of contemporary rural teenagers are mainly manifested as life safety problems and mental health problems, and there are three main reasons for these problems, namely, the rural teenagers’ own level, school level and society level. In addition, specific and feasible solutions are put forward to address the existing life safety problems and mental health problems, that is to give play to the role of main school and teachers in all subjects, attach importance to physical education and mental health classes, and strengthen the cooperation between schools and parents to achieve the cooperation between home and school, so that we can jointly strengthen life safety education for rural teenagers and promote their healthy growth.
Linfoma B difuso de células grandes asociado a KSHV/HHV8 con áreas focales de enfermedad de Castleman multicéntrico: reporte de un caso inusual y revisión de la literatura
Authors: Caviedes Cleves Mario Alberto , Diaz Macea Dilia Rosa , Santiago Pacheco Vanessa
Published: April 2023

Las lesiones linfoproliferativas de aspecto plasmablástico/plasmocitoide asociadas a KSHV/HHV8 en pacientes con infección por virus de la inmunodeficiencia humana (VIH) más frecuentemente encontradas incluyen la enfermedad de Castleman multicéntrica (ECM), el linfoma B difuso de células grandes asociado a KSHV/HHV8 (LBDCG KSHV/ HHV8+), el linfoma primario de cavidades, el linfoma primario de cavidades extracavitario y el más recientemente descrito síndrome inflamatorio de citoquinas asociado al KSHV/HHV8 (KICS). Más que entidades separadas, se las considera un espectro de manifestaciones clínicas asociadas a la infección por KSHV/HHV8. Los pacientes con sarcoma de Kaposi tienen mayor riesgo de desarrollar ECM, y a su vez éstos, cuando se acompañan de agregados plasmablásticos, tienen mayor probabilidad de progresar a linfoma franco asociado a KSHV/HHV8. Se presenta el caso de un paciente masculino de 42 años, con VIH/SIDA y sarcoma de Kaposi en quien posteriormente se evidenció histopatológicamente áreas de ECM con LBDCG KSHV/HHV8+. Adicionalmente, se hace una revisión de la literatura del diagnóstico diferencial de este espectro de entidades.
Linfoma de células T paniculítico: a propósito de un caso
Authors: Tarqui Apaza Melissa Casandra , Vargas Garcia Lorena Andrea , Gregorio Carina Edith , Rosero Guerrero Juan Manuel , Sanchez Sanchez Joselyn Gabriela , Enrico Mattos Alicia Ines , Ponzinibbio Carlos
Published: April 2023

El linfoma de células T paniculítico representa menos del 1% de todos los linfomas no Hodgkin. Se distingue por placas y nódulos subcutáneos y es más frecuente en mujeres. El curso clínico puede ser desde indolente hasta agresivo asociado a síndrome hemofagocítico, presentando mal pronóstico y respuesta pobre al tratamiento. En este reporte de caso clínico hacemos mención a un paciente con linfoma de células T paniculítico cuyo único síntoma inicial fue fiebre prolongada que posteriormente agregó leucopenia y la aparición de nódulos de pequeño tamaño en miembros superiores.
Análise da dessonorização e da sonorização das consoantes oclusivas e fricativas do português em contato com o alemão
Authors: Schneiders Michele , Busse Sanimar
Published: April 2023

Este artigo tem como temática a variação de dessonorização e sonorização das consoantes oclusivas e fricativas do português em contato com o alemão, sendo o objetivo geral da pesquisa analisar o fenômeno de dessonorização e sonorização das consoantes oclusivas e fricativas do português em contato com o alemão em falantes bilíngues de três localidades do Extremo Oeste de Santa Catarina a partir dos dados coletados pelo Atlas das Línguas em Contato na Fronteira (ALCF), projeto de pesquisa vinculado à Universidade Federal da Fronteira Sul (UFFS) Campus Chapecó (SC). A análise é pautada na seguinte pergunta de pesquisa: quais contextos extralinguísticos atuam como condicionadores para a realização da variação de dessonorização e sonorização das consoantes oclusivas e fricativas do português em contato com o alemão? A base teórica e metodológica da Dialetologia Pluridimensional e Relacional orienta a análise (RADTKE; THUN, 1996; THUN, 1998; 2005; 2010), a qual descreve a língua a partir de diferentes dimensões. Neste estudo, investigamos a variação por meio da dimensão diatópica, diastrática e diageracional. Como resultado, os dados revelam que tanto a variação de dessonorização quanto a de sonorização ocorre na fala dos bilíngues, sendo que a idade junto à baixa escolaridade são fatores importantes no condicionamento dos fenômenos.
An Efficient Intelligent Oil Well Monitoring System for Niger Delta Oil Fields
Authors: Julius B. Wosowei  , Chandrasekar Shastry
Published: April 2023

Oil well monitoring has metamorphosed over the years from Dump Wells completion and the era of permanent gauges through to the hydraulic control wells until this era of intelligent Well completion. These efforts are geared towards an era where Well data can be collected and interpreted with no human intervention. The aim is to improve recovery (optimization), minimized OPEX and CAPEX, and general efficiency. However, intelligent monitoring by virtue of intelligent Well completion is still an expensive venture. The paper presents an efficient IoT-based monitoring system whereby an ESP32 microcontroller and sensors are used to monitor the Well pressure, temperature, level, and flow rate on a real-time basis. The data from the oil well is available to the user at any remote location because the sensor data is sent to a cloud service on the internet. The cloud service used is the MQTT protocol and the MIT APP Inventor. The sensor data is also viewed in an android Mobile App
La arquitectura es inevitable
Authors: Álvarez Isidro Eva M. , Gómez Alfonso Carlos J.
Published: April 2023

La obra de Jaque y Office for Political Innovation es mucho más amplia que lo que este número de [En Blanco. Revista de Arquitectura] muestra, no siendo el objetivo hacer un repaso minucioso por ella porque sería extensísimo: muchos son los proyectos de este grupo que han producido, no solo nuevos objetos sino, sobre todo, nuevas teorías, nuevas disquisiciones, y siempre a través del cuestionamiento del proyecto. Sin embargo, y dado el enfoque de esta revista centrada en el hormigón, es interesante observar, en el discurrir de Jaque por la cultura material, cómo para él y sus colaboradores, los materiales no son aptos o no aptos en sí mismos, sino que se piensan como posibles o no, en función de sus características y contexto, en un marco de referencia mucho más amplio y creíble, dando cabida a construcciones en las que abunda el hormigón.
Distanciamientos temporales. El Jardín de los Ángeles de John Hejduk en Riga
Authors: Barberá Pastor Carlos
Published: April 2023

En la plaza principal del proyecto Riga, de John Hejduk, se ubican El Edificio del Tiempo, El Centro de Cultura y El Jardín de los Ángeles. El Edificio del Tiempo mantiene vínculos con los edificios que colindan según el uso y el programa de cada una de sus arquitecturas. A partir de la memoria propuesta en el proyecto,  este trabajo plantea la hipótesis de que John Hejduk expresa una sensación amarga al aludir al aroma que dejan los ángeles cuando se posan en las ramas de los árboles. Mediante el manuscrito, se trata de averiguar si las acciones que se suceden entre los edificios de alrededor influyen en tal desolación. La investigación explora los edificios colindantes para encontrar el sentido que se dan entre ellos. El ensayo trata de descubrir dónde se encuentra ese sentimiento de irritación que de algún modo expresa el proyecto Riga mediante los trazos, los colores y los tonos de los dibujos así como los vínculos con Marcel Proust, Michel Foucault y Walter Benjamin. Como conclusión, la aflicción planteada está causada por la falta de arquitectura tan necesaria para la vida en la ciudad cuando el arquitecto deja de lado su condición propia.
Trazados geométricos en la carpintería de los palacios valencianos: estudio de teselaciones
Authors: Soler Estrela Alba
Published: April 2023

La arquitectura valenciana vivió un momento de esplendor durante los siglos XIV, XV y XVI en un tiempo de desarrollo económico, en correspondencia con la expansión por el Mediterráneo de la Corona de Aragón. Personajes nobles construyen casas señoriales y palacios que destacan por su riqueza arquitectónica, y acabados decorativos. Entre ellos cabe señalar los dibujos geométricos de la carpintería de sus puertas y ventanas, que resultan característicos de este tipo de edificio en la época y entorno geográfico mencionado. En algunos casos pueden suponerse originales, pero dadas sus características, es un elemento que ha podido sufrir renovaciones y sustituciones, en algunos casos datadas en el siglo XX. Se presenta una aportación a su conocimiento, aplicando una metodología de análisis de los trazados decorativos, que puede ser complementaria a estudios de tipo histórico, dentro de un enfoque multidisciplinar. A partir de un número representativo de casos se analiza la generación de formas en base a las teselaciones regulares y semirregulares, descubriéndose un variado repertorio. Ello permite establecer una clasificación y descripción de los distintos tipos, que se definen gráficamente y se ilustran con ejemplos de aplicación concreta y de adaptación a las formas de las portadas y ventanales.
Crono-huella del Cuarto Real de Sto. Domingo: Geometría del espacio en el tiempo
Authors: Martínez Ramos e Iruela Roser , Fernández Martín Lídia , Garcia Nofuentes Juan Francisco
Published: April 2023

El Cuarto Real de Santo Domingo de Granada, declarado Bien de Interés Cultural en 1919, alberga uno de los edificios conservados referentes del período de transición entre el arte almohade y nazarí. Situado en el llamado barrio de El Realejo, en el entorno de lo que fuera el de Alfareros, este conjunto palatino ha sido objeto de importantes y controvertidas intervenciones a lo largo de su historia. El presente estudio propone una metodología que estructura la exploración sobre su materialidad utilizando como herramienta de indagación una línea del tiempo fundamentada en aquella información arqueológica que incluye aspectos perceptivos de los espacios y las formas. Sobre este cronograma se establecen los hitos asociados a las principales transformaciones, explorándose las características de los sistemas constructivos principales sobre los que se establece la condición espacio-temporal de la arquitectura y el lugar, poniendo en valor la trascendencia de los invariantes relacionados con la geometría y condición material en la definición de la huella arquitectónica de este singular patrimonio.
Are physicians fully aware of the potential transgenerational and multigenerational effects of a large opioid misuse in the population?
Authors: Coppola, MD Maurizio , Mondola, MD Raffaella
Published: April 2023

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Opioid analgesics prescription in people with and without cancer in France
Authors: Janah, PhD Candidate Asmaa , Bouhnik, PhD Anne-Déborah , Cortaredona, MSc Sébastien , Mancini, MD, PhD Julien , Bousquet, MD, PhD Philippe Jean , Peretti-Watel, PhD Patrick , Bendiane, MSc Marc-Karim
Published: April 2023

Introduction and Objectives: According to World Health Organization recommendations, opioids prescription is a key aspect of improvement in cancer pain relief. However, studies on opioids prescription in France are scarce. This study aimed principally to investigate the impact of cancer on opioids prescription and then to identify factors associated with this prescription, focusing on patients' characteristics impact.Methods: We matched the following two cohorts: cancer survivors (N = 6,760) and individuals without cancer (N = 6,760). Using French health insurance databases, we compared the prevalence of prescribed opioids in 2009-2015 in people with and without cancer and we applied afterwards conditional Poisson regressions to estimate relative risks for monthly opioids prescription. For cancer survivors only (N = 3,055), multivariate negative binomial regressions were performed to identify factors associated with opioids prescription.Results: Cancer was associated with a higher analgesics prescription in the cancer population. While Step II and III opioids prescription decreased over time, the latter remained marginal and tended to stabilize. Older people were most adversely affected by underprescription of opioids, especially Step III opioids. Furthermore, although the matched case/control study suggested that men were prescribed opioids more often than women, multivariate analysis did not support this finding.Conclusion: The inconsistency between our findings and existing literature regarding both opioids prescription trends and postdiagnosis pain chronicity in cancer survivors over the medium term suggests possible changes in pain perception and the evolution of cancer pain management strategies. Further research should explore these hypotheses and investigate patient characteristics' effect in cancer pain management.
Impact of rescheduling hydrocodone-combination products in an urban Texas county healthcare system
Authors: Shumway, MD John W. , Ran, MD Renzhong , McClusky, BS, Pharm Jeff , Rafique, MD Zubaid , Dark, MD, MPH Cedric , Peacock, MD W. Frank , Cintron, MD Alexie , Ludwig, MD, MPH, PhD Michelle
Published: April 2023

Objective: The objective of this study was to examine the rescheduling of hydrocodone- combination products (HCPs) and associated changes in prescriber patterns in an urban county healthcare system in Texas.Methods: Pharmacy data were obtained electronically for tramadol, hydrocodone-acetaminophen, and acetaminophen-codeine from 180 days before and after the schedule change on October 6, 2014. χ2 and t tests were used to calculate the significance of changes between the medications over the studied time.Results: Hydrocodone-acetaminophen saw a decline in dispense events and pills dispensed of 80.2 and 67.9 percent, respectively, in the immediate 30-day period following the scheduling change with a total decrease of 80.8 and 67.5 percent, respectively, in the 180-day period. Acetaminophen-codeine dispense events and total pills dispensed increased by 302.3 and 288.9 percent, respectively, in the immediate 30-day period while 180-day results experienced an increase of 215.1 and 209.8 percent, respectively. There were no major changes with tramadol. Additionally, an increase of 69.5 percent in pills per dispense event of hydrocodone-acetaminophen was noted in the 180-day period following the schedule change.Conclusion: The scheduling change of HCPs is associated with an immediate decrease in hydrocodone-acetaminophen use at our institution while a simultaneous rise in acetaminophen-codeine products was observed.
Opioid use: Case-control analyses of worker's compensation data
Authors: Ott, PhD, MSPH Ulrike , Thiese, PhD, MSPH Matthew S. , Ronna, BS Brenden B. , Hegmann, MSPH, CIC Kristine , Hegmann, MD, MSPH Kurt T.
Published: April 2023

Objectives: Working-age adults are disproportionately impacted by opioid misuse. Factors associated with opioid misuse in people with workers compensation (WC) claims are not well studied. WC in some states is a “captured” market making it a more efficient site for researching the opioids epidemic. A pilot study was conducted to identify factors associated with opioid use using a large WC insurer's claims in Utah.Methods: This was a case-control study using a large WC insurer's database. We conducted secondary data analyses of a de-identified dataset originally obtained from the WC insurer. Cases were defined as claims with a morphine equivalent dose (MED) ≥50 mg/d in the 30 days after the claim was filed while controls = 0 mg/d.Results: A total of 76 patient's claims (28 cases and 48 controls) were included in the final data analyses. The majority of claimants were male (N = 50, 65.8 percent), worked full time (N = 58, 76.3 percent) and had a mean age of 37.0 ± 11.4 years. The majority of controls filed medical only claims (N = 40, 83.3 percent) while the majority of cases filed indemnity claims (N = 19, 67.9 percent). Cases were prescribed a mean MED of 126.4 (SD = 93.3) within the first month after filing the claim. Most cases visited > 3 medical providers (N = 13, 46.4 percent) in the first month after filing the claim while the majority of controls only visited one provider (N = 28, 58.3 percent). Remarkably, the mean number of providers visited within the first month for the cases was 3.8, which was 2-fold greater than the control group. Exploratory multivariate analyses showed that cases were 4.6 times more likely to have visited 2-3 medical providers (p = 0.025), and 41.8 times more likely to have visited more than three medical providers (p < 0.001). Cases had 3.6 higher odds of having been prescribed nonsteroidal anti-inflammatory prescription within the first month as compared to controls (p = 0.014).Conclusion: This pilot study found risk factors, some of which may be modifiable. We aim to conduct a large study using existing WC data to create a scoring system that identifies those claimants at higher risk of adverse opioid-related events that may have preventive applications at a systems-level.
Pharmacists’ perspectives on opioid stewardship challenges
Authors: Westcott, PharmD, BCPS Kristina L. , Swanson, RPh Andrea K. , Zavaleta, MHSA Kathryn W. , Gazelka, MD Halena M. , Philpot, PhD Lindsey M. , Cunningham, PharmD, RPh Julie L.
Published: April 2023

Objective: Pharmacists are in a distinctive position to champion opioid stewardship principles in communications with prescribers and patients. This effort is focused on elucidating perceived barriers to uphold these principles observed in pharmacy practice.

Design: Qualitative research study.

Setting: A healthcare system, consisting of inpatient and outpatient settings across several United States (US) states in both rural and academic settings.

Participants: Twenty-six pharmacists who represented the study setting in the sole healthcare system.

Interventions: Five virtual focus groups were conducted with the 26 pharmacists from inpatient and outpatient settings across four states in both rural and academic settings. Trained moderators conducted 1-hour focus group meetings that consisted of a mix of poll and discussion questions.

Main outcome measure: Participant questions were related to awareness, knowledge, and system issues affecting opioid stewardship.

Results: All pharmacists reported their routine follow-up with prescribers when questions or concerns arise but noted workload as a barrier to meticulous review of opioid prescriptions. Participants highlighted best practices, including transparency on the rationale for guideline exceptions to improve the management of after-hours concerns. Suggestions were integration of guidelines into prescriber and pharmacist order review workflows and a more visible prescriber review of prescription drug monitoring programs.

Conclusions: Improvements in communication and transparency of information related to opioid prescribing between pharmacists and prescribers would enhance opioid stewardship. Integration of opioid guidelines into opioid ordering and review would improve efficiency, guideline adherence, and, most importantly, patient care.
Tramadol utilization among patients with higher risk of adverse drug events: A claims analysis of commercially insured and Medicare Advantage members
Authors: Borrelli, PhD, PharmD, MBA Eric P. , Bratberg, PharmD, FAPhA Jeffrey , Greaney, PhD, MPH Mary L. , Kogut, PhD, MBA, RPh Stephen J.
Published: April 2023

Objective: To assess prescribing of tramadol among patients with contraindications and higher risks of adverse events in a large population of commercially insured and Medicare Advantage members.

Design: We performed a cross-sectional analysis evaluating tramadol utilization in patients with higher risk of adverse outcomes.

Setting: This study utilized 2016-2017 data from the Optum Clinformatics Data Mart.

Patients and participants: Patients with at least one tramadol prescription without a cancer or sickle cell diagnosis during the study period.

Main outcome measures: We first determined if tramadol was prescribed among patients with contraindications or risk factors for adverse outcomes. We then determined if patient demographic or clinical factors were associated with the use of tramadol in these higher-risk scenarios using multivariable logistic regression models.

Results: Among patients with at least one prescription for tramadol, 19.66 percent (99 percent CI: 19.57-19.75) concurrently received an interacting cytochrome P450 isoenzyme medication, 19.24 percent (99 percent CI: 19.15-19.33) concurrently received a serotonergic medication, and 7.93 percent (99 percent CI: 7.88-8.00) concurrently received a benzodiazepine. Additionally, 1.59 percent (99 percent CI: 1.56-1.61) of patients who received tramadol also had a seizure disorder, while 0.55 percent (99 percent CI: 0.53-0.56) of patients were under the age of 18. Overall, nearly one in three patients (31.17 percent) received tramadol in the presence of at least one of these risks (99 percent CI: 31.06-31.27).

Conclusion: Almost one in three patients prescribed tramadol had a clinically significant drug interaction or contraindication for use, suggesting that prescribers often disregard these concerns. Real-world studies are needed to better understand the likelihood of harms associated with the use of tramadol in these contexts.
Volume 19, Number 3
Authors: Opioid Management Journal of
Published: April 2023

May/June 2023