bluuebunny/crossref_metadata_2025 huggingface dataset:
Silver-Coated Waste Rubber Micro-Particles with Low Density, High Stability, and Excellent Electromagnetic Shielding Ability: Design, Preparation, and Characterization
Authors: Lv Xin-Kun , Zhong Qi , Li Yong-Kun , Yu Jin-Gang
Published: April 2024

Introduction:

The electromagnetic radiation caused by the increasing application of
electronic devices is associated with environmental hazards and health risks.

Methods:

With the rapid development of science and technology, it is urgent to reduce electromagnetic
interference by introducing effective electromagnetic shielding materials. Furthermore,
novel electromagnetic shielding materials with increasing stability and decreasing density have
become the focus of the current research. Herein, silver (Ag) coated rubber (AR) micro-particles
(MPs) were prepared by coating Ag nanoparticles (NPs) onto waste AR MPs.

Results:

The AR MPs not only exhibited superior electromagnetic shielding performance with
the electromagnetic interference (EMI) shielding effectiveness (SE) value of 6.1 dB at 5.8 GHz,
but also possessed excellent long-time stability (240 h) in high-temperature (85 °C) and high
humidity (85% RH) environment. Due to the low density (0.66 g/cm3) of AR-3 MPs, its practical
application in lightweight and highly integrated electronic devices is guaranteed.

Conclusion:

The developed AR MPs have exhibited broad application prospects in the electromagnetic
interference (EMI) shielding field due to the good EMI shielding performance, high
stability and low density.
Acceleration of Wound Healing in Diabetic Rats through a Novel 3D Organo-Hydrogel Nanocomposite of Polydopamine/TiO2 Nanoparticles and Cu (PDA-TiO2@Cu)
Authors: Elekhtiar Sally A. , Gazia Maha Mohamed Abo , Helal Azza I. , Mahfouz Hala , El-Kemary Nesma M. , Abd-Elsalam Sherief , Elksass Samar , Alkabes Hend A. , El-Kemary Maged , Abd-Elsalam Marwa M.
Published: April 2024

Background:

Diabetic wound represents a serious issue with a substantial impact and
an exceptionally complex pathology affecting patients’ mental health and quality of life. So, we
have developed a novel 3D organo-hydrogel nanocomposite of polydopamine/TiO2 nanoparticles
and cu (PDA-TiO2@Cu) and examined its efficacy in diabetic wound healing.

Methods:

Forty-five adult male albino rats were divided into normal control rats (non-diabetic
rats with non-treated skin wounds), diabetic control rats (diabetic rats with non-treated skin
wounds), and organo-hydrogel-treated rats (diabetic wounds treated with topically applied organo-
hydrogel once daily). Macroscopic changes of the wound were observed on days 0, 3, 5, 7,
and 10 to measure wound diameters. Skin specimens from the wound tissue were taken on days
3, 7, and 10, respectively, and examined histologically and immunohistochemically. Also, the
gene expressions of collagen I, Matrix Metalloproteinase-9 (MMP-9), and Epidermal Growth
Factor (EGF), and levels of Interleukin 6 (IL-6) and Superoxide Dismutase (SOD) were assessed.

Results:

Our observed results indicated that the developed patch significantly accelerated the
healing time compared to the normal control and diabetic control groups. Moreover, the patchloaded
group revealed complete re-epithelization and a highly significant increase in the mean
area % of CD31 immunostaining on day 7. The organo-hydrogel-loaded group displayed a significant
decrease in gene expression of MMP-9 and a significant increase in gene expression of
EGF and collagen I. Additionally, the organo-hydrogel-loaded group exhibited a significant decrease
in levels of IL-6 and a significant increase in levels of SOD, compared to the normal diabetic
control groups.

Conclusion:

The organo-hydrogel can be used for treating and decreasing the healing period of
diabetic wounds.
Lightweight Underwater Target Detection Method based on Improved YOLOv5s
Authors: Mi Yongfa , Chi Mingshan , Zhang Qiang , Liu Pengjie , Sun Fangyang
Published: April 2024

Introduction:

In the target detection technology of underwater robots, many patents and
papers have aimed to enhance the accuracy of underwater target detection, but limited resources in
underwater robots overlook lightweight detection methods.

Method:

In this study, we proposed an underwater target detection method using lightweight devices
while ensuring high accuracy that could be maintained with limited resources. Our proposed algorithm
leveraged the Ghost lightweight network, EMA mechanism, and CARAFE up-sampling technology
to enhance YOLOv5s. To validate our method, comparative experiments, visual analysis, and
ablation experiments were conducted.

Results:

The experimental results showed that our algorithm had a model size of only 9.7 M, with
4.38×106 parameters and a computational volume of 8.4 GFLOPs. Precision, recall, and mAP@0.5
increased by 4.2%, 2.2%, and 2.5%, respectively

Conclusion:

Our improved algorithm provided an efficient and accurate solution for underwater
robot target detection technology.
Factors for Implementing Medical Cannabis Cultivation in Brazil
Authors: de Oliveira Danielle Louzada , Amaral Ana Claudia Fernandes , de Souza Ramos Aline
Published: April 2024

:

The medicinal properties of the Cannabis genus are evident and many studies indicate its
usefulness to treat many diseases. However, the production of Cannabis-based products has been
hampered by its criminalization. Currently its cultivation is not allowed in Brazil, except in specific
situations. It increases the price of Cannabis-based products, as it requires the importation of inputs,
making it difficult for most of the population to access such medicines. In this context, this review
presents an overview of Brazilian legislation on medical Cannabis and the current market for Cannabis
products in Brazil. The main goal is to encourage the cultivation of medical Cannabis and the
distribution of its products by the Brazilian Unified Health System. In addition, it presents recommendations
to implement cultivation based on a bibliographic survey carried out in scientific databases
and clinical evidence of the effectiveness of Cannabis in treating patients suffering from several
diseases and conditions, although more complete studies are needed to confirm both risk-benefit
relationship and dose to be administered. After searching for legislation and bills on government
websites, it became evident that there was a need for changes in Brazilian legislation to enable cultivation
in Brazil. However, there are several proposals for legislation in progress, and Brazil can significantly
benefit from this therapeutic option.
Hippocampal Serotonin and Responses to Immobilization Stress in Rats
Treated with Metformin
Authors: Afroz Rushda , Salman Tabinda , Nawaz Shazia , Mustafa Nazish , Zafar Munnum , Haleem Darakhshan Jabeen
Published: April 2024

Background:

Stress-related illnesses and depression are rising in modern society. Selective
serotonin reuptake inhibitors as well as other antidepressants, are also not very effective and
commonly exhibit partial remission, suggesting the need for novel therapeutic agents for treating
anxiety and depression.

Objective:

The present study was designed to investigate serotonergic mechanisms in the potential
anxiolytic and stress-reducing effects of metformin.

Method:

In the first experiment, rats were given two doses (50 and 100mg/kg) of metformin to
monitor the effects of repeated administration on motor activity, anxiety, and 5-HT-1A receptor
expression in the hippocampus and raphe nuclei. The second experiment was conducted in 2 parts,
in 2a. experiment, control, and metformin (50 mg/kg) treated rats were immobilized for 2 hours for
5 consecutive days. Food intake and body weight were monitored daily and anxiety-like behavior
was monitored on days 2 and 6. On day 6, rats were again immobilized for 2 hours, and after termination
of stress rats were sacrificed to collect the hippocampus for HPLC-EC analysis of serotonin
(5-hydroxytryptamine; 5-HT) and 5-hydroxy indole acetic acid (5-HIAA). In 2b. experiment,
control, and metformin (50 mg/kg) treated rats were immobilized for 2 hours, and after 2 hours rats
were sacrificed to collect the hippocampus for HPLC-EC analysis of 5-HT and 5-HIAA.

Results:

We found that metformin treatment exhibited anxiety reduction associated with greater
expression of 5-HT-1A receptor in the hippocampus and reduced expression in the raphe nuclei.
Immobilization stress-induced food intake and body weight deficits were comparable in control
and metformin-treated rats, but the anxiogenic effects of stress were smaller in the metformintreated
group. Stress-induced decreases of hippocampal 5-HT were smaller in metformin-treated
than in control rats.

Conclusion:

Metformin can reduce stress-induced anxiety mediated via an increase in hippocampal
5-HT levels and 5-HT-1A heteroreceptor expression.
Formulation Optimization and Characterization of Tizanidine Hydrochloride-loaded Gold Nanoparticles Using Quality by Design Approach
Authors: Kamble Milind Dharmraj , Gaikwad Mahesh , Marathe Rajendra , Shirsat Mahendra , Tapadiya Ganesh
Published: April 2024

Background:

Gold nanoparticles (GNP) have been used extensively in cancer biologics
and as drug carrier systems for improved pharmacokinetics and effective therapeutic action. GNPs
also ensure reliable diagnosis with sensitive imaging.

Objective:

This study aimed to synthesize tizanidine hydrochloride (TZN)-biodegradable gold (Au)
nanoparticles by the reduction of chloroauric acid (HAuCl4) with trisodium citrate using a microwave
synthesizer and quality by design approach.

Methods:

The formulation method used was optimized using a 32 (two-factor, three-level design)
factorial experiment. Temperature (X1) and concentration of gold salt (X2) were the two independent
factors, and particle size (Y1), Percent drug entrapment efficiency (Y2), and polydispersity index
(Y3) were the responses recorded for the study.

Results:

The results of the study revealed that the optimized nanoparticles (TGN8) had a particle
size (Y1) of 195 ± 1.2 nm, a polydispersity index of 0.2, and entrapment efficiency of 99.0 ± 2.9%
at an optimized concentration of 14 mM gold salt (X1) and 100°C temperature (X2). Atomic Force
Microscopy showed the spherical shape particles. In vitro drug release was found to be 62.1 ± 0.5%
release of TZN in simulated gastric buffer (pH 1.2) and 45.5 ± 2.8% in physiological buffer (pH
7.4).

Conclusion:

Overall, the study identified the optimal formulation conditions for TZN GNPs by
considering the effects of independent variables on desired responses.
RES-CMCNPs Enhance Antioxidant, Proinflammatory, and Sensitivity of Tumor Solids to γ-irradiation in EAC-Bearing Mice
Authors: Mansour Mohamed S. , Mahmoud Amira A. , Sayah Mohannad A. , Mohamed Zahraa N. , Hussein Mohammed A. , ALsherif Diana A.
Published: April 2024

Objectives:

Resveratrol (Res) is a bifunctional compound found in numerous plants, including
grapes and mulberries. Nanotechnology has promising applications in medicine. The ability
of various nanomaterials to serve as radiosensitizers against tumor cells were reported in several
manuscripts. The present investigation aimed to assess the antitumor and radiosensitizing effects of
Res-CMCNPs on EAC-bearing mice.

Methods:

Res-CMCNPs have been developed using the CMC emulsification cross-linking technique.
Entrapment efficiency (%), particle size, Polydispersity index and ZETA potential, UV, FTIR
spectra, and drug release were evaluated and described for RES-CMCNPs. The radiosensitizing
properties of RES-CMCNPs were also evaluated in vitro and in vivo against EAC-carrying rodents.
The LD50 of Res-CMCNPs was estimated and its 1/20 LD50 was prepared for treating EAC transplanted
mice.

Results:

The results revealed that the Res-CMCNPs exhibited a high entrapment efficiency
(85.46%) and a size of approximately 184.60 ±17.36 nm with zeta potential value equals -51.866
mv. Also, the UV spectra of Res and Res-CMCNPs have strong absorption at 225 and 290 nm. The
percentage of resveratrol release at pHs 5.8 and 7.4 was found to be 56.73% and 51.60%, respectively,
after 24 h at 100 rpm. Also, the FTIR analysis confirmed the chemical stability of resveratrol in
Res-CMCNPs cross-linking. The IC50 values of Res-CMCNPs against EAC cells viability were
32.99, 25.46, and 22.21 μg after 24-, 48- and 72 h incubation, respectively, whereas those of Res-
CMCNPs in combination with γ-irradiation after 6-, 10 and 12-mins exposure were 24.07, 16.06 and
7.48 μg, respectively. Also, the LD50 of Res-CMCNPs was 2180 mg/kg.b.w. The treatment of
EAC-bearing mice with Res-CMCNPs plus γ-irradiation improved plasma levels of NO, caspase-3,
P53 and NF-kB levels as well as liver MDA, GSH, SOD, CAT, LT-B4, aromatase, Bax, Bcl2 and
TGF-β levels and exhibited more significant anticancer activity than administration of Res-
CMCNPs and/or exposure to γ-irradiation individually. On the other hand, administration of Res-
CMCNPs in combination with γ-irradiation attenuated liver mRNAs (21, 29b, 181a, and 451) gene
expression.

Conclusion:

Grafting resveratrol onto carboxymethyl chitosan appears to be a promising strategy
for cancer therapy as a radiosensitizer, potentiating tumor cells' sensitivity to radiation by improving
levels of proinflammatory features and antioxidant biomarkers.
Antimicrobial Nano-coatings of Ti Surfaces for Anti-inflammatory Aims in Dental Implants
Authors: Masoudi Sahar , Torab Ali , Negahdari Ramin , Maleki Dizaj Solmaz , Sharifi Simin , Mosayebzadeh Amin
Published: April 2024

Introduction:

Coating of dental implants with nanoparticles can lead to improved fixation
of implants.

Aim:

The aim of this study was to review the reported antimicrobial nano-coatings of Ti surfaces
(dental implants) for anti-inflammatory, tissue integration, and osteogeneration aims.

Methods:

The data were collected from Google Scholar, PubMed, and Scopus sources.

Results:

The results showed that the antimicrobial nano-coatings of Ti surfaces exhibited a reduction
in initial bacterial adhesion, concomitantly with an increase in the attachment of human gingival
fibroblasts. In addition, the application of these surfaces resulted in anti-inflammatory effects
with different mechanisms. Some nano-coated titanium surfaces have also shown enhanced hydrophilicity
and corrosion resistance, aiding the adhesion and proliferation of osteoblasts.

Conclusion:

Coating Ti surfaces with antimicrobial nanoparticles can improve soft tissue integration
and osteogeneration, leading to improved fixation of implants. Moreover, such coatings may
profit biocompatible surfaces with a controlled release profile for the antimicrobial agents.
Polymersomes: A Novel Approach for Cancer Theranostics
Authors: Yadav Soniya , Patel Asha , Ahlawat Priyanka , Panjawani Drishti , Patel Shruti
Published: April 2024

Background:

In the recent epochs of advancement in the field of oncology, polymersomes-
based drug delivery systems have witnessed a significant breakthrough. Nano-sized carriers
formed from amphiphilic block-copolymers, have distinctive compositions and structures, enabling
them to encapsulate a diverse range of compounds.

Objective:

This comprehensive review aims to highlight the significant advancements reflecting
progress made in the past few decades and their potential in cancer treatments, offering a promising
future for improved patient outcomes and as a tool for theranostics.

Method:

Different approaches for synthesizing nanocarriers with distinct responsive characteristics
have been mentioned. Redox-responsive polymersomes are designed, and their self-assembly
behavior is studied. pH-responsive are created using specific copolymers, while enzyme-responsive
ones are engineered to degrade in the presence of lysosomal enzymes using various approaches
like thin-film hydration, nanoprecipitation, etc.

Result:

Polymersomes have exhibited remarkable breakthroughs in cancer theranostics and addressed
various challenges associated with drug targeting, diminishing the toxicity, and related issues,
exhibiting advantages such as enhanced stability, prolonged circulation time, and the ability
to encapsulate both hydrophilic and hydrophobic substances. Over the past few decades, they have
been proven as a breakthrough approach for cancer therapy.

Conclusion:

Polymersomes present a promising platform for advancing cancer therapeutics and diagnostics,
offering a multifunctional approach that combines targeted drug delivery with imaging
capabilities. Their versatility makes them valuable tools for researchers and practitioners in the
field of medicine.
Cannabidiol (CBD) Listed as a Drug of Abuse by the Italian Health Ministry: Expert Opinion
Authors: Comacchio Carla , Balestrieri Matteo , Colizzi Marco
Published: April 2024

:

In August 2023, the Italian Health Ministry listed cannabidiol (CBD) as a drug of
abuse. This rekindled the debate on the medical and non-medical use of cannabis. The most discussed
topics are risks related to the use of cannabis, the decriminalization/legalization of recreational
cannabis, and use of cannabis-based drugs for medical purposes. The decision to include
CBD in the “Unique Text for drugs of abuse” (DPR.309/1990), along with the already included
main psychoactive component of cannabis, delta-9-tetrahydrocannabinol (THC), is not particularly
relevant to such ongoing discussions. Even when it comes to cannabis-based drugs for medical
purposes, such a decision will have a minimum impact on CBD-based medical prescriptions. Instead,
a high economic impact is expected on CBD-based products sold online or in specific
shops, including the so-called “cannabis-light”, formally sold as a “technological product” for collection
purposes but used as over-the-counter drugs for the treatment of several medical conditions.
Cannabis-light products have reduced regular drug consumption by about 10%. Also, they
are not entirely safe, as the actual content of THC may significantly differ from the one stated,
carrying unexpected health risks. Further, CBD is likely not a drug with addictive potential; however,
its uncontrolled use for medical purposes needs to be regulated as the court battles are ongoing.
The Mind of the Dead and the Thinking (Johnny Got His Gun)
Authors: Yıldız Ersan
Published: April 2024

Written as an anti-war novel by Dalton Trumbo in 1938, 'Johnny Got His
Gun' was released in 1971 as a film directed by Trumbo. In the narrative that begins
with Joe Bonham's serious injury, we witness episodes from Bonham's life before the
war, the dreams he had, and the events in the hospital that made him an object.
Bonham's state of being in between fantasy and reality is also embedded in the visual
language of the film, strengthening the narrative and the message conveyed. The antiwar
message that Trumbo wanted to express could reach people in different media such
as novels, movies, music, video clips, and theater with Joe Bonham's story. It is
possible to make different inferences when looking at the film from an architectural
point of view rather than its anti-war messages. The narrative created with the film
reveals the importance of the body and space relationship in an extraordinary way for
the person who experiences the space not only with his eyes but to the extent his body
allows. 'Johnny Got His Gun' is examined with the view that architecture is an art open
to sensory experiences where all senses are fused.
The Da Vinci Code
Authors: Benian Esin
Published: April 2024

The Da Vinci Code is a film adaptation of Dan Brown's bestselling novel of the same name. Both art and architecture are employed as instruments to support the space of the film, which was shot in 2006. While the film takes the audience to the streets of Paris and London, historical sites, and art galleries, it also leads the audience to a tremendous secret. As a result, the film is addressed in terms of 'looking and seeing' in this study. Looking and seeing are not only not synonymous, but they are also distinct notions in terms of perception. It is possible that we do not see everything we look at. There are, however, a number of works that must be seen while watching this film. The study's goal is to call attention to the works that should be examined in the film from this perspective. The works in question are also explored under two subcategories: architecture and art. When looking at the locations used in the film, religious architecture such as churches, monasteries, and chapels stand out. Aside from religious structures, the buildings that have become city emblems draw attention, particularly in the scenes shot in France. Symbols and works of art, as well as settings and architecture, were employed to reinforce and strengthen the space of The Da Vinci Code. The “pentacle” sign, the Mona Lisa, and the Last Supper painting are among them. As a result, this film, whose book set records and had a huge impact, should be seen by everybody who enjoys suspense, mystery, puzzle solving, architecture, and art; and at the same time, what is looked at must be seen as well.
The Instances of Time and Space: Cloud Atlas
Authors: Aydın Ali
Published: April 2024

The film Cloud Atlas is one of the cult works of science fiction cinema. It was created to set a shared narrative of time and space in six different stories. The theme of the film, directed by Lana and Lilly Wachowski siblings, is the wicked history of humanity, which does not distinguish between time and space. Throughout the film, the phenomena of time and space are employed as frequently used narrative tools. The phenomena of time and space also have an important place in both the theoretical and practical fields of architecture. Therefore, based on these two phenomena, the movie Cloud Atlas is a work that should be consulted as it has the potential to enrich our singular perception of time and space to which we are prone. Throughout the film, the places serve as the litmus of the times the stories belong to. It gives the history of the role of space in the history of humanity and shows how our relationship with space and the meanings we attribute to it are transformed. Thus, the multidimensional relationship that space has established over time is skillfully conveyed to the architects stuck in today's space through cinematography. In this context, considering the social, cultural, and economic life when the six stories in the film took place, their effects on the phenomenon of space are discussed. The spatial descriptions of these six different stories that the directors wanted to create will be examined one by one. As a result, these multidimensional effects of time have once again emphasized the importance of not thinking about time independently of space. The fact that the organization of space, from the most primitive life forms to the life forms where technology reaches its peaks, is also a reflection of the social structure of the period reveals the multidimensional relationship of space. Themes such as racism, war, consumption fetishism, and technophobic visioning of the future in the stories also overlap with the spatial setups. According to the story, the place can take on the symbol of power, the instrument of domination, and virtual setups that we have not yet experienced. Thus, the potential of cinema to dissolve the past and the future in its own temporality and transfer it to the audience already expands the limits of imagination to a broader temporality for architects who are trapped in the hegemony of the unconditional present.
Pharmacology in Geriatric Anesthesia
Authors: D’Souza Reuben , Hsu George
Published: April 2024

In terms of different pharmacokinetic and pharmacodynamic interactions,
geriatric patients exhibit greater sensitivity to anesthetics. Therefore, understanding the
differences in body composition, hepatic and renal function, changes in protein
binding, and minimal alveolar concentration are the key to titration of anesthetics in
geriatric patients. In addition, polypharmacy, use of non-prescription medications and
adverse medications related events warrant special considerations for the geriatric
population, more so than in their younger counterparts. Lastly, careful titration of
anesthetics may minimize the development of postoperative delirium and postoperative
cognitive dysfunction, which are associated with higher morbidity, mortality, length of
hospitalization, and overall cost.
Post-Operative Care of Elderly Patients
Authors: Madison Rachel , Brotman Ian
Published: April 2024

Geriatric patients have unique postoperative concerns that must be
considered to safely guide their care. In this chapter, we discuss the commonly
encountered complications in the post-anesthesia care unit with a focus on
postoperative delirium, postoperative nausea, and vomiting, as well as issues relating to
renal, respiratory, and cardiovascular systems with advancing age. Finally, we discuss
opioid and nonopioid analgesic considerations unique to this vulnerable patient
population.
Anesthetic Considerations for a Patient with a Cardiovascular Implantable Electronic Device (CIED)
Authors: Shah Dave , Trivedi Keyur , Patel Kinjal
Published: April 2024

As the number of patients and use of cardiovascular implantable electronic
devices have increased, anesthesiologists must understand the different types of
implanted devices and their management during the perioperative period. Caring for
these patients requires knowledge of the standard nomenclature used to describe device
function, the role of a magnet, and the differential responses a magnet can cause based
on the device type.
Geriatric Pain Patient
Authors: Sagir Afrin , Woolley Parker , Chen Fangyu
Published: April 2024

Chronic pain is a major cause of physical disability, poor mental health, and
decreased quality of life [1,2]. The burden of chronic pain is reflected in increased
medical care utilization and consequently increased healthcare costs, which are
estimated at an astounding $560 billion per year [3]. CDC estimates from 2019 reveal
that while 20.4% of adults in the USA live with chronic pain, the prevalence increases
with advancing age [4]. 30.8% of people aged 65 years and above had chronic pain
while 11.8% of them had high-impact chronic pain, which is defined as pain that
causes significant restriction of self-care, social and work-related activities [5]. The
impact of chronic pain is more severe in the elderly; older adults report poorer physical
health and disability in comparison to younger adults [6-8]. Chronic pain in the elderly
is also associated with poorer sleep, cognitive decline, dementia, and death [9-13].
With the projected increase in the elderly population in the US every year, the burden
of chronic pain is only expected to increase. This chapter outlines the physiologic and
pharmacologic changes that happen with ageing, the major causes of chronic pain in
the elderly, as well as the myriad of treatment options available with a focus on
pharmacotherapy, behavioral and alternative therapies, and interventional pain
therapies. The focus of treatment is not only targeted towards reducing pain but special
considerations should be made to minimize the cognitive effects of polypharmacy in
light of multiple comorbidities and promote mental well-being and functional
independence [14].
BEDEN EĞİTİMİ ÖĞRETMENLERİN SPORCU KİMLİKLERİYLE TEKNOSTRES DÜZEYLERİ ARASINDAKİ İLİŞKİNİN BELİRLENMESİ.
Authors: Atasoy Murat , Bolat Kâmil
Published: April 2024

Çalışmada beden eğitimi öğretmenlerinin sporcu kimlikleriyle teknostres düzeyleri arasındaki ilişkinin belirlenmesi amaçlanmıştır. Betimsel tarama modelinin kullanıldığı araştırma 2022-2023 yılları arasında T.C. Milli Eğitim Bakanlığı ve/veya bağlı özel okullarda faal olarak görev alan 162’ si erkek 63’ ü kadın olmak üzere toplam 225 beden eğitimi öğretmeni katılmıştır. Araştırmada verilerin elde edilmesinde; araştırmacı tarafından geliştirilen beş maddelik “Tanılayıcı Bilgi Formu”, Çoklar ve diğ. (2017) tarafından Türk kültürüne uyarlama çalışmaları yapılan “Öğretmenlerin Teknostres Düzeylerini Belirleme Ölçeği” ve Brewer vd., (2001) tarafından geliştirilen Türkçeye uyarlaması ise Öztürk ve Canan, (2013) tarafından yapılan “Sporcu Kimliği Ölçeği” kullanılmıştır. Verilerin çarpıklık ve basıklık değerlerin normal dağım göstermesi sebebiyle parametrik testlerler uygulanmış, VIF değerinin 5’ ten küçük olması nedeniyle sonuç çoklu doğrusal regresyon analizi yapılmıştır. Araştırmanın analizleri sonucunda beden eğitimi öğretmenlerinin: demografik değişkenden gelir düzeyi, yaş ve medeni durum açısından teknostres düzeylerinde farklılık anlamlıyken; tüm değişkenlere yönelik analizde sporcu kimlik düzeyinde farklılık tespit edilmemiştir. Öğretmenlerin sporcu kimlikleri ile teknostres düzeyleri arasında anlamlı bir ilişki bulunmasına rağmen sporcu kimlikleri alt boyutlarının öğretmenlerin teknostres düzeylerini anlamlı düzeyde etkilediği belirlenmiştir. Sonuç olarak beden eğitimi öğretmenlerinde gelir düzeyi, yaş ve medeni durum gibi değişkenlerin teknostres düzeylerinde önem arz ettiğini ayrıca teknostres düzeylerini sporcu kimliklerinden sosyal kimliğin azaltıcı, olumsuz duyuşsallığın artırıcı etkisi olduğu sonucuna ulaşılmıştır.
LGS’YE HAZIRLANAN 8.SINIF ÖĞRENCİLERİNİN SINAV KAYGISI DÜZEYLERİ İLE BEDEN EĞİTİMİ DERSİ TUTUMLARI ARASINDAKİ İLİŞKİNİN İNCELENMESİ
Authors: Balgamış Muhammet , Akgül Mehmet Haşim
Published: April 2024

Bu araştırmada LGS’ye hazırlanan 8. Sınıf öğrencilerinin sınav kaygısı düzeyleri ile beden eğitimi dersi tutumları arasındaki ilişkinin incelenmesi amaçlanmıştır. Araştırma ilişkisel analiz tekniğine dayalı betimsel bir araştırmadır. Bu kapsamda 2022-2023 Eğitim-Öğretim yılında MEB’e bağlı Burdur İl merkezinde öğrenim görmekte olan Lgs’na girecek öğrenciler bu araştırmanın evrenini oluşturmaktadır. Araştırmanın örneklemi ise 445 öğrenciden oluşmaktadır. Veri toplama aracı olarak “Westside Sınav Kaygısı Ölçeği” ve “Beden Eğitimi Tutum Ölçeği” kullanılmıştır. Araştırmada toplanan verilerin analizi için SPSS 21.0 programından yararlanılmıştır. Araştırma bulgularına göre, cinsiyet, aktif lisanslı sporcu olma, aile aylık gelir düzeyi değişkenleri ile öğrencilerin sınav kaygısı düzeyleri ve beden eğitimi dersi tutum düzeyleri arasında istatistiksel olarak anlamlı farklılıklar tespit edilmiştir. Yapılan korelasyon analizi sonucunda ise, öğrencilerin sınav kaygı düzeyleri ile beden eğitim dersine olan tutumları arasında anlamlı bir ilişki görülmemiştir. Sonuç olarak, öğrencilerin bazı demografik değişkenlerinin, sınav kaygısı düzeylerini ve beden eğitimi dersi tutumlarını olumlu-olumsuz etkilediği söylenebilir.
ÜNİVERSİTE ÖĞRENCİLERİNİN BENLİK SAYGISI DÜZEYİ YORDAYICILARI: DUYGUSAL ZEKA VE OTANTİKLİK
Authors: Şiraz Mehmet Fatih , Akyıl Yusuf , Çağlar Azmi
Published: April 2024

Benlik saygısı bireylerin mutlu olmasından başa çıkma becerilerine kadar etkililiği bulunan bir kavramdır. Bu bağlamda araştırmamızda temel amaç duygusal zeka ve otantiklik düzeylerinin benlik saygısı ile ilişkisini ve bu ilişkideki yordayıcı etkileri belirlemek hedeflenmektedir. Araştırmanın örneklemi 310 kız, 106 erkek olmak üzere toplamda 416 üniversite öğrencisinden oluşmaktadır. Araştırmada demografik veri formu, Duygusal Zeka Özelliği Ölçeği–Kısa Formu, Otantiklik Ölçeği ve İki Boyutlu Benlik Saygısı Ölçeği kullanılmıştır. Araştırmada elde edilen sonuçlara göre, duygusal zeka, otantiklik ve benlik saygısı arasında anlamlı ilişkiler bulunmuştur. Duygusal zeka ve otantiklik ise benlik saygısının alt boyutlarından kendini sevme varyansının % 55, öz yeterlilik varyansının % 40 açıkladığı sonucuna varılmıştır. Sağlık psikolojik danışmanlığı çerçevesinde ruh sağlığı alanında verilen hizmetlerde, çift ya da grup psikoterapilerinde benlik saygısını arttırmaya odaklanan çalışmalarda duygusal zeka ve otantikliği arttırmaya yönelik müdahaleler geliştirilebilir.
ÖZEL EĞİTİM BÖLÜMÜ ÖĞRENCİLERİNİN DOĞAL AFET OKURYAZARLIK DÜZEYLERİNİN ÇEŞİTLİ DEĞİŞKENLER AÇISINDAN İNCELENMESİ
Authors: Yıldırım Fatma
Published: April 2024

Doğal afet okur-yazarlığı, doğal afet öncesi sırası ve sonrası hazırlık ve müdahale için önemli bir unsurdur. Özellikle özel eğitim bölümü öğrencilerinin bu beceriye sahip olması ile özel gereksinimi olan öğrencilerin ve ailelerinin doğal afetler konusunda bilgilendirilmesinde başrol oynamaktadır. Bundan dolayı özel eğitim bölümü öğrencilerinin doğal afet okur-yazarlık düzeyleri, çeşitli değişkenler açısından incelenmiştir. Araştırmada verilerin analizi için istatiksel paket program kullanılmıştır. Analizde kullanılan testler; bağımsız örneklem t-testi, anova ve ancova testleri kullanılmıştır. Araştırma sonucunda, bağımsız örneklem t-testine göre özel eğitim bölümü erkek öğrencilerin lehine doğal afet okur-yazarlık düzeyinin özel eğitim bölümü kadın öğrencilerinkine göre anlamlı farklılık göstermiştir. Anova testi sonucunda ise sınıf düzeyleri açından 2. Sınıf özel eğitim öğrencilerinin lehine 4. Sınıf özel eğitim öğrencilerinin düzeyinden anlamlı farklılık saptanmıştır. Ancova testi sonucunda hem cinsiyet hem de sınıf düzeyine göre psikolojik dayanıklılık kontrol atına alındığında özel eğitim bölümü öğrencilerinin doğal afet oku-yazarlığı anlamlı düzeydedir. Doğal afet oku-yazarlığa ilişkin derslerin üniversitelerde zorunlu ders olması ve doğal afetlere yönelik farkındalık uygulamaların sivil toplum kuruluşlarıyla yapılması önerilmekle birlikte sonuçlar literatür kapsamında tartışılmıştır.
Redefining Health Care Data Interoperability: Empirical Exploration of Large Language Models in Information Exchange
Authors: Yoon Dukyong , Han Changho , Kim Dong Won , Kim Songsoo , Bae SungA , Ryu Jee An , Choi Yujin
Published: April 2024

Background

Efficient data exchange and health care interoperability are impeded by medical records often being in nonstandardized or unstructured natural language format. Advanced language models, such as large language models (LLMs), may help overcome current challenges in information exchange.

Objective

This study aims to evaluate the capability of LLMs in transforming and transferring health care data to support interoperability.

Methods

Using data from the Medical Information Mart for Intensive Care III and UK Biobank, the study conducted 3 experiments. Experiment 1 assessed the accuracy of transforming structured laboratory results into unstructured format. Experiment 2 explored the conversion of diagnostic codes between the coding frameworks of the ICD-9-CM (International Classification of Diseases, Ninth Revision, Clinical Modification), and Systematized Nomenclature of Medicine Clinical Terms (SNOMED-CT) using a traditional mapping table and a text-based approach facilitated by the LLM ChatGPT. Experiment 3 focused on extracting targeted information from unstructured records that included comprehensive clinical information (discharge notes).

Results

The text-based approach showed a high conversion accuracy in transforming laboratory results (experiment 1) and an enhanced consistency in diagnostic code conversion, particularly for frequently used diagnostic names, compared with the traditional mapping approach (experiment 2). In experiment 3, the LLM showed a positive predictive value of 87.2% in extracting generic drug names.

Conclusions

This study highlighted the potential role of LLMs in significantly improving health care data interoperability, demonstrated by their high accuracy and efficiency in data transformation and exchange. The LLMs hold vast potential for enhancing medical data exchange without complex standardization for medical terms and data structure.
Identification and Speciation of Non-diphtheritic Corynebacteria (NDC) and their Antimicrobial Susceptibility Pattern by Broth Microdilution
Authors: Chandra Pratibha , Ravi G.S. , Pasha S.A. Rahil , Kumar Rakesh
Published: April 2024

Non-diphtheritic Corynebacteria (NDC), originally considered contaminants in clinical samples, have now emerged as nosocomial pathogens, emphasising the importance of their identification and prompt reporting. 120 non-diphtheritic corynebacteria isolated from pus were chosen for examination. A battery of tests identified isolates and minimum inhibitory concentration (MIC) was detected by broth micro-dilution and interpreted as per Clinical & Laboratory Standards Institute (CLSI) and British Society for Antimicrobial Chemotherapy (BSAC) guidelines. C. amycolatum 28 (31%), followed by C. striatum 18 (20.5%) was the predominant isolate. Cephalosporins were least effective followed by Gentamycin. However, all isolates were sensitive to Vancomycin and Linezolid. Our research highlights the necessity of implementing clinical antimicrobial therapy protocols for Corynebacterium spp. Empirical treatment with vancomycin or linezolid is recommended until in vitro susceptibility results become accessible.
Brain Tumor Detection using Deep Learning
Authors: Kadam Vivek
Published: April 2024

Abstract: A tumor is an abnormal swelling or growth that is caused by the division of the cells in the nervous system. A brain tumor is one of the most dangerous types of tumors. There are four different types of brain tumor. The treatment for brain tumors is determined by the type, grade, and locationof the tumor. If the tumor is not detected early, it can be fatal. MRI images are used to diagnose brain tumors. The accuracy of the results depends on the expertise and domain knowledge of the experts, and it is also a very time-consuming and costly process. In order to overcome these limitations, several deep learning algorithms for the detection of brain tumors have been proposed.
A Deep Learning Approach for Real-Time Sign Language Detection and Response through Avatar Model
Authors: I Siva Sankari
Published: April 2024

Abstract: This paper focuses on the evolution of a real-time sign language detection model using computer vision, machine learning, and deep learning. Its goal is to narrow the poor communication for the speaking and hearing-impaired community by using recurrent neural networks and long short-term memory models. The proposed system utilizes a dataset comprising sign language gestures captured in various contexts and by different signers. Preprocessing techniques are applied to draw out fitting features from the video frames, including hand movements, facial expressions, and body postures. The LSTM neural network architecture is chosen to grab temporal dependencies in sequential data, making it suitable for the robust nature of sign language. The training process involves optimizing the LSTM network on the labeled dataset, incorporating techniques such as transfer learning and data augmentation to enhance model generalization. The resulting model is capable of recognizing a divergent set of sign language actions in real-time
Optimized Transfer Learning Based Dementia Prediction System for Rehabilitation Therapy Planning
Authors: P Bhaskar , B Naga Upendra , Y Shashidhar Reddy , B Chandra Dileep Kumar Reddy , M Naga Niranjan Reddy
Published: April 2024

Abstract: Dementia is a progressive neurodegenerative disease leading to cognitive decline, and current medical interventions can only slow its progression. Early prediction of dementia onset holds potential for preventive measures. This study aims to develop a machine learning model using transfer learning from magnetic resonance imaging (MRI) data to predict dementia. The project employs k-fold cross-validation and various parameter optimization algorithms during model training to enhance prediction accuracy. The final voting classifier and optimized Transfer Learning algorithms achieved an impressive accuracy, surpassing the performance of competing methods on the same dataset. This suggests the efficacy of the proposed transferlearning approach in predicting dementia data. The developed model enables early diagnosis of dementia, a crucial factor in halting neurological deterioration associated with the disease. This is particularly relevant for regions with limited access to human physicians, providing a valuable tool for underserved populations. The proposed system holds promise for planning rehabilitation therapy programs for dementia patients. As a tool for early diagnosis and intervention, the model not only contributes to improved patient outcomes but also addresses the challenges faced by regions lacking access to sufficient healthcare resources. And also include ensemble methods (Voting Classifier, Stacking Classifier) and a hybrid CNN-LSTM approach are employed for improving accuracy, with the Voting Classifier achieving an impressive 100% accuracy. To facilitate user testing, a user-friendly front end using the Flask framework, incorporating user authentication, was proposed for seamless application of this advanced dementia prediction system.
Investigation of the Relationship Between Communication and Problem Solving Skills of Physical Education and Sports Teachers
Authors: Keskin Memiş , Yıldırım Mehmet
Published: April 2024

Bu araştırma, beden eğitimi ve spor öğretmenlerinin iletişim ve problem çözme becerileri arasındaki ilişkinin incelenmesi amacıyla yapılmıştır. Araştırmaya devlet ve özel okullarda görev yapan 239 kadın 461 erkek olmak üzere toplam 700 beden eğitimi ve spor öğretmeni gönüllü olarak katılmıştır. Araştırmada veri toplama aracı olarak öğretmenlerin kişisel özelliklerini belirlemek için araştırmacı tarafından oluşturulan “Kişisel Bilgi Formu”, iletişim becerilerini belirlemek için Korkut Owen ve Demirbaş-Çelik (2017) tarafından uyarlanan “İletişim Becerileri Ölçeği Yetişkin Formu” ve son olarak problem çözme becerilerini belirlemek için Heppner ve Petersen (1982) tarafından geliştirilen ve Türkçe’ ye uyarlaması Şahin ve Heppner (1993) tarafından yapılan “Problem Çözme Ölçeği” kullanılmıştır. Verilerin analizinde öncelikle katılımcıların kişisel özelliklerini belirlemeye ilişkin betimleyici frekans (n), yüzde (%), aritmetik ortalama ( ) ve standart sapma (ss) kullanılmıştır. Verilerin analizinde normal dağılım için bağımsız gruplar t-testi ve One Way Anova testleri, gruplar arasındaki farkı belirlemek için ise post-hoc Scheffe testi kullanılmıştır. Normal olmayan dağılımlar için ise Mann-Whitney U ve Kruskal Wallis testleri kullanılmış, gruplar arasında farklılaştığını belirlemek üzere Hypothesis Test Summary Testi kullanılmıştır. Aralarındaki ilişkiyi ortaya koymak için Pearson Çarpım Moment Korelasyon Analiz testine bakılmıştır. Araştırmada iletişim düzeyleri ile problem çözme ölçeği alt boyutlarından aceleci yaklaşım arasında ters yönde bir ilişki olduğu, diğer iletişim düzeyleri ve problem çözme ölçeği alt boyutlarının tamamında değişkenler arasında aynı yönde bir ilişki olduğu tespit edilmiştir. Bununla birlikte beden eğitimi ve spor öğretmenlerinin iletişim becerileri yükseldikçe problem çözme becerilerinin de yükseldiği söylenebilir.
Investigation of Acute Effects of Using Different Density Foam Roller Models on Hamstring Muscle Stiffness and Flexibility in Professional Soccer Players
Authors: Ağaoğlu Muhammet Maksut , Usgu Serkan , Canıtez Ağaoğlu Berna , Seyhan Sinan
Published: April 2024

It was aimed to examine the acute effects of the use of foam roller models of different densities on hamstring muscle stiffness and flexibility in professional soccer players. Hamstring muscle's stiffness were evaluated using the Myoton Pro device. The flexybility of the hamstring muscle were evaluated using with the unilateral sit-reach test on 21 male professional soccer players who played in Gaziantep Soccer Club at aged 18-40. Athletes were randomly divided into groups of seven to use soft, medium and hard foam rollers. The athletes applied the method consisting of two sets of one minute on the dominant hamstring muscle. Measurements were made twice, before the application (BA) and after the application (AA). The muscle stiffness measurement of the soccer players was determined BA mean of 16.26 N/m and AA mean of 16.17 N/m.. Flexibility measurement was determined BA mean of 28,36 cm and AA mean of 31,05 cm. It was found that the mean of pre-test and post-test did not differ statistically for muscle stiffness (p>0,05) according to measurement times, but statistically differed for flexibility (p0,05). It shows that foam roller application is important for increasing muscle flexibility, but there is no difference between foam roller models applied at different intensities in terms of removing muscle stiffness and increasing flexibility.
PENGARUH PROBLEM BASED LEARNING DAN KEMAMPUAN BERPIKIR KRITIS TERHADAP HASIL BELAJAR MAHASISWA
Authors: Wulandari Nadiah , - Sjarkawi , M Damris
Published: April 2024

The present study investigates the effect of problem-based learning (PBL) and critical thinking skill variables on studentsâ€™ achievements. The independent variables are PBL design instructional and the expository and discussion learning design instructional. The moderator variable is the level of critical thinking skills which was measured by the adaptation test from Cornell Test, California Critical Thinking Test, and Ennis Weir Essay Test. The experiment uses 2 x 2 factorial design with pretest and posttest. Participants are the students majoring in Industrial Engineering. The study was done in two groups: the PBL group and the Conventional group with 30 students of each of the group. Two Way ANOVA and Tukey Test are applied in the data analysis. The study revealed that there was a significant difference between the experiment and the control group on studentsâ€™ achievements. The similar results also found on students with high critical thinking skills. There was also an interaction between teaching approach and critical thinking skills in effecting studentsâ€™ achievement. Keywords: problem based learning, critical thinking skills, cognitive result of learning, and affective assessment
Phytoplankton in estuaries adapt to salinity stress by increasing the content and unsaturation of the thylakoid lipid MGDG
Authors: Gašparović Blaženka , Novak Tihana , Godrijan Jelena , Vrana Ivna , Kazazić Snježana , Penezić Abra , Čanković ⎜Milan , Ljubešić Zrinka , Hrustić ⎜Enis , Mlakar ⎜Marina , Du Jinzhou , Zhang Ruifeng , Zhu ⎜Zhuoyi
Published: April 2024

Life in estuaries, especially in surface waters, is a challenge,
particularly due to changes in salinity. Environmental changes
inevitably lead to acclimation or adaptation of phytoplankton in order
to survive. Since membranes are the first to perceive changes in the
environment, we focused on understanding how phytoplankton in estuaries
adapt to salinity stress through lipid remodeling. Since photosynthesis
is one of the most sensitive processes, we studied the response of
phytoplankton thylakoid membrane lipids to salinity stress. The study
was conducted in two estuaries with completely different environmental
characteristics. Apart from hydrology, estuaries also differ in
phytoplankton community compositions, nutrient status and temperature.
Here we show that estuarine phytoplankton, regardless of environmental
differences in the two estuaries studied, increase
monogalactosyldiacylglycerol (MGDG) content and unsaturation in response
to osmotic shock to protect photosynthetic machinery. This was
particularly pronounced at the lowest salinities when freshwater
phytoplankton encounter saline water and decreases with increasing
salinity. Our results also suggest that increased concentrations of
nitrogen nutrients have a positive effect on the increased unsaturation
of MGDG. Finally, we speculate that the freshwater green algae are the
major group responsible for the observed largest increased and content
of unsaturated MGDG at the lowest salinity.
Corrigendum
Authors: Editorial E
Published: April 2024

The authors of the article: Samarbakhsh, L., Tasic, B.: What makes a board
director better connected? Evidence from graph theory. Computer Science and
Information Systems, Vol. 17, No. 2, 357-377. (2020),
https://doi.org/10.2298/CSIS190628045S have informed the Editorial Office
that they missed acknowledging two facts: 1. The authors Dr. Laleh
Samarbakhsh and Dr. Boza Tasic would like to thank Ted Rogers School of
Management for funding support as part of the TRSM Research Development
Grant. 2. The authors would like to acknowledge the contribution of Dr Hamid
Ebrahimi and ask that he be added as a third co-author to the paper. Their
decision is based on a recent reflection on the unique circumstances
regarding Dr Ebrahimi?s involvement in the paper. Therefore, the journal is
publishing this Corrigendum. The authors of this article should be listed as
follows: Laleh Samarbakhsh, Boza Tasic, Hamid Ebrahimi.

 Link to the corrected article 10.2298/CSIS190628045S