bluuebunny/crossref_metadata_2025 huggingface dataset:
Finanzpolitische Zeitenwende – das Fundament für Wachstum schaffen
Authors: Lindner Christian
Published: August 2023

In this article, German Finance Minister Christian Lindner places the government’s draft of the 2024 federal budget and the fiscal plan up to 2027 in the context of his fiscal policy strategy and identifies the need for further action. In order to be able to set priorities for strengthening future-oriented spending, the federal government has reviewed all expenditure in the federal budget. Action is being taken to raise savings potentials and to curb expenditure trends. However, in view of challenges such as demografic change or the transition towards climate neutrality, further steps must follow in order to ensure that the federal budget’s composition and priorities are rigorously targeted towards future-oriented tasks, and to enhance the attractiveness of Germany as a business location through supply-side measures.
Unternehmen befürchten dauerhafte Kostenbelastungen
Authors: Grömling Michael , Bardt Hubertus
Published: August 2023

The high inflation rates as a consequence of the energy price crisis, which began with the Russian war of aggression on Ukraine, were associated with considerable problems not only for private consumers, but also for companies. For Germany, a high-cost country, further cost increases are problematic for its international competitiveness. Within the framework of the IW business survey, the burden of various cost categories was measured. The increase in wage costs in particular is perceived by almost 40% of the companies surveyed as at least a strong additional burden, which is seen by practically all companies as a permanent burden. Energy, natural resources and material costs, on the other hand, which have characterised the past year, are seen as a permanent burden for competitiveness by two-thirds of the companies. Together with a further increase in permanent regulatory burdens, there are fears of a permanent deterioration for Germany as a production location.
PERAN MOTIVASI KERJA MEMEDIASI PENGARUH PELATIHAN DAN PENGEMBANGAN KARIR TERHADAP KINERJA KARYAWAN RISATA BALI RESORT AND SPA
Authors: Anggreni Kadek Intan , Adnyani I Gusti Ayu Dewi
Published: August 2023

Bali has many businesses engaged in hospitality services and the majority of people work in tourism, therefore, hotels need to pay attention to the performance of their human resources to always improve the quality of the company. The purpose of this study was to examine the role of motivation in mediating the effect of training and career development on employee performance. The basic theory used to explain the conceptual model in this study is Maslow's needs theory. This research was conducted at Risata Bali Resort and Spa. Respondents in this study were all employees with permanent status with a total of 76 employees. The data collection techniques used are questionnaires and interviews. The techniques used in this research are path analysis and sobel test. The results of data analysis show that training and career development have a positive and significant effect on work motivation, training, career development and work motivation have a positive and significant effect on employee performance, and work motivation is able to mediate the effect of training and career development on employee performance. Employee performance can be improved by optimizing training and career development so as to increase employee motivation and performance.

Keyword: training, career development, employee perfomance, motivation.
UJI EFEKTIVITAS EKSTRAK ETANOL DAUN CENGKEH (Syzygium aromaticum L.) TERHADAP PERTUMBUHAN METHICILLIN RESISTANT Staphylococcus aureus SECARA IN VITRO
Authors: Dewi Cokorda Istri Dyah Yustika , Ernawati Desak Ketut , Widhiartini Ida Ayu Alit
Published: August 2023

ABSTRAK

Staphylococcus aureus merupakan salah satu patogen yang menjadi penyebab utama infeksi nosokomial. Staphylococcus aureus merupakan ancaman serius dikarenakan resistensinya terhadap antibiotik metichillin sehingga disebut juga sebagai Methicillin-resistant Staphylococcus aureus (MRSA). Namun obat pilihan saat ini menimbulkan efek samping yang tidak diinginkan, oleh karena itu perlu dikembangkan sumber lain untuk terapi MRSA. Salah satu tanaman yang potensial untuk MRSA adalah daun cengkeh (Syzygium aromaticum L.). Penelitian ini bertujuan untuk mengetahui aktivitas antibaketri esktrak etanol daun cengkeh (Syzygium aromaticum L.) terhadap pertumbuhan MRSA secara in vitro. Penelitian ini adalah True Experimental Post Test Only Group Design dengan metode disc diffusion untuk menilai zona hambat dari ekstrak dengan konsentrasi 10%, 20%, dan 50% yang dibuat terhadap bakteri MRSA dengan 6 kali pengulangan. Hasil penelitian menunjukan bahwa rerata diameter zona hambat yang dihasilkan oleh konsentrasi 10%, 20%, dan 50% secara berturut-turut yaitu  9,50 ± 0,54 mm, 12,33 ± 0,81 mm, dan 14,66 ± 1,50 mm. berdasarkan hasil penelitian ini, dapat disimpulkan peningkatan konsentrasi esktrak etanol daun cengkeh berpengaruh terhadap diameter zona hambat MRSA yang dihasilkan dari percobaan secara in vitro.

Kata kunci : Syzygium aromaticum L., zona hambat, MRSA
SKALA NYERI PADA PASIEN KANKER PAYUDARA YANG DIRAWAT DI RUMAH SAKIT UMUM PUSAT SANGLAH PADA BULAN OKTOBER 2019
Authors: Widyadari Kadek Santi Diahswari , Adiputra Putu Anda Tusta , Wetan Ni Gusti Ayu Agung Manik Yuniawaty
Published: August 2023

ABSTRAK

Nyeri adalah suatu sensasi tidak menyenangkan yang dapat bersifat sensorik maupun emosional dan berkaitan dengan adanya kerusakan jaringan. Nyeri sering kali menjadi alasan utama seorang pasien, terutama pasien kanker untuk mencari pengobatan. Penelitian ini bertujuan untuk menentukan intensitas nyeri yang dialami pasien kanker payudara yang dirawat di Rumah Sakit Umum Pusat Sanglah. Penelitian ini merupakan penelitian dengan metode deskriptif cross-sectional. Penelitian ini melibatkan pasien yang telah terdiagnosis kanker payudara yang dirawat jalan di Poliklinik Bedah Onkologi Rumah Sakit Umum Pusat Sanglah pada bulan Oktober 2019. Sampel dipilih melalui metode consecutive sampling. Data diambil dari data primer berupa kuesioner yang berisi identitas pasien, diagnosis kanker payudara, dan skala nyeri berupa skala Numeric Rating Scale (NRS). Responden paling banyak berada direntang umur 41-50 tahun. Seluruh subjek adalah perempuan. Lebih banyak kanker berada pada sisi kiri payudara. Responden paling banyak berada pada stadium II. Hasil penelitian menunjukkan dari total 50 sampel, sebanyak 10 orang (20%) tidak mengalami nyeri, 6 orang (12%) mengalami nyeri ringan, 26 orang (52%) mengalami nyeri sedang, 6 orang (12%) mengalami nyeri berat, dan 2 orang (4%) mengalami nyeri sangat berat. Intensitas nyeri yang paling banyak dijumpai adalah nyeri dengan intensitas sedang.

 

Kata kunci : Skala nyeri numerik (NRS), intensitas nyeri, kanker payudara.
PROPORSI DAN KARAKTERISTIK AKNE VULGARIS PADA MAHASISWA PROGRAM STUDI SARJANA KEDOKTERAN DAN PROFESI DOKTER FAKULTAS KEDOKTERAN UNIVERSITAS UDAYANA TAHUN 2019
Authors: Roxanne Joanne , Indira I Gusti Ayu Agung Elis , Adiguna Made Swastika , Karmila I Gusti Ayu Agung Dwi
Published: August 2023

ABSTRAK

Latar Belakang: Akne vulgaris (AV) merupakan penyakit yang umum terjadi pada remaja dan merupakan penyakit multifaktorial.

Tujuan: Penelitian ini bertujuan untuk mengetahui proporsi dan karakteristik (jenis, distribusi, dan klasifikasi tingkat keparahan) serta beberapa faktor pencetus yang menyertai kejadian AV pada mahasiswa kedokteran yang sebagian besar dalam usia remaja

Metode: Penelitian ini merupakan penelitian potong lintang deskriptif. Pengambilan data dilakukan dengan menggunakan formulir pengambilan data dilanjutkan dengan pemeriksaan lesi oleh peneliti. 

Hasil: Terdapat 87 (70,2%) dari 124 peserta penelitian yang terdiagnosis AV pada Mahasiswa Program Studi Sarjana Kedokteran dan Pendidikan Dokter Fakultas Kedokteran Universitas Udayana tahun 2019. Laki-laki lebih banyak mengalami AV (51,7%) dibandingkan perempuan (48,7%). Jenis lesi yang paling banyak ditemukan adalah komedo dengan tingkat klasifikasi ringan dan distribusi lesi paling banyak pada wajah. Komplikasi yang paling banyak terjadi adalah hiperpigmentasi. Diagnosis AV lebih banyak ditegakan pada subjek yang tidak memiliki riwayat keluarga, jarang membersihkan wajah (<3 kali sehari). Tercatat penggunaan masker bahan alami dalam penanganan AV yaitu spirulina, tomat, madu dan teh hijau 

Kata Kunci: Akne vulgaris, Proporsi, Karakteristik, Faktor Pencetus
HUBUNGAN FAKTOR RISIKO DENGAN ANGKA KEJADIAN KELAINAN REFRAKSI MAHASISWA TAHUN PERTAMA FAKULTAS KEDOKTERAN UNIVERSITAS UDAYANA
Authors: Pradnyandari Ni Wayan Jayanti , Juliari I Gusti Ayu Made , Kusumadjaja Made Agus , Siska S
Published: August 2023

ABSTRAK

Kelainan refraksi merupakan gangguan penglihatan yang dapat menyebabkan gangguan pada kehidupan sehari-hari hingga kebutaan. Prevalensi kebutaan dan gangguan penglihatan di Indonesia yang disebabkan oleh kelainan refraksi sebesar 22,1% dan 15% diantaranya merupakan anak usia sekolah. Kejadian kelainan refraksi dapat disebabkan oleh berbagai faktor risiko seperti usia, jenis kelamin, riwayat keluarga, dan aktivitas melihat dekat seperti menggunakan laptop dan gadget. Tujuan dari penelitian ini adalah mengetahui hubungan faktor risiko dengan angka kejadian kelainan refraksi pada mahasiswa tahun pertama Program Studi Sarjana Kedokteran dan Profesi Dokter Fakultas Kedokteran Universitas Udayana. Penelitian ini merupakan penelitian analitik dengan desain penelitian cross sectional dengan menggunakan 218 responden sebagai sampel penelitian. Proporsi kejadian kelainan refraksi pada mahasiswa tahun pertama di Fakultas Kedokteran Universitas Udayana adalah sebanyak 139 dari 218 responden (63.8%). Kelainan refraksi yang paling banyak terjadi adalah miopia yaitu sebanyak 125 responden (57.3%). Berdasarkan hasil penelitian didapatkan adanya hubungan yang signifikan antara riwayat keluarga responden dengan angka kejadian kelainan refraksi (p=0,000;95% CI 1.683(1.270–2.230)), dan terdapat hubungan yang signifikan antara jarak membaca buku dengan angka kejadian kelainan refraksi (p=0.001;95% CI 1.411(1.127–1.765)). Sehingga dapat disimpulkan bahwa riwayat keluarga dan jarak membaca buku merupakan faktor risiko yang secara signifikan berpengaruh terhadap angka kejadian kelainan refraksi.

Kata kunci: kelainan refraksi, faktor risiko, mahasiswa tahun pertama
KARAKTERISTIK PENDERITA CACAR AIR (VARICELLA) DI RUMAH SAKIT UMUM PUSAT SANGLAH, DENPASAR PERIODE APRIL 2015 - APRIL 2016
Authors: Murtia Margha Ni Putu Tiza , Wardhana Made
Published: August 2023

Varisella merupakan penyakit yang mudah menular pada manusia, manusia adalah satu-satunya inang pada penyakit ini. Hal ini disebabkan oleh Varicella Zoster Virus, virus yang termasuk bagian dari alpha-herpes yang merupakan jenis virus imunogenik. Sebagai penyakit endemik akut yang paling umum yang menyerang manusia. Hal ini merupakan masalah setiap orang tua hadapi pada anak-anaknya, dan varicella juga bisa terjadi di pada dewasa, varicella biasanya dikenal sebagai cacar air. Tujuan dari penelitian ini adalah untuk mengetahui pola varicella pada pasien pada periode Rumah Sakit Sanglah April 2015-April 2016. Pendekatan penelitian ini menggunakan studi deskriptif desain penelitian retrospektif. Sampel ditentukan dengan menggunakan teknik total sampling, dalam sampel penelitian ini yang digunakan adalah semua pasien pada Rumah Sakit Sanglah periode April 2015-April 2016 yang terinfeksi infeksi varicella. Data yang diperoleh dalam penelitian ini diolah secara deskriptif. Hasil penelitian secara deskriptif menunjukkan bahwa 56 orang yang terinfeksi varicella di Rumah Sakit Sanglah, mayoritas pasien yang terinfeksi dengan varicella berada dalam kelompok usia 0 sampai 15 tahun dengan total 30 orang (53,6%), berdasarkan perbedaan jenis kelamin menunjukkan bahwa pasien wanita memiliki insiden tertinggi yaitu 27 orang (48,2%) daripada laki-laki dan hampir mirip jumlahnya. Tidak ada komplikasi dari semua kriteria inklusi yang mana 56 orang (100%). Dan lokasi lesi tersering adalah pada kepala dan ektremitas bagian atas dengan jumlah 26 orang (46,4 %).

Kata kunci: varicella, umur, jenis kelamin, komplikasi, lokasi lesi.
CLINICAL CHARACTERISTICS OF SQUAMOUS INTRAEPITHELIAL LESION (SIL) PATIENTS AT SANGLAH RSUP DENPASAR 2015-2019
Authors: Patuan Jonathan Yoshua
Published: August 2023

Cervical cancer is a malignant disease that attacks the cervix uteri. Before the cancer phase, it will begin with precancerous lesions or Squamous Intraepithelial Lesion (SIL), which often do not cause complaints or symptoms. Therefore, regular screening is needed to detect precancerous lesions. One of the most widely used screening programs is the Pap smear method. The purpose of this study was to determine the clinicopathological characteristics of SIL patients at Sanglah Hospital Denpasar in 2018 - 2019. This study was a descriptive study with a cross sectional study design. Total sampling was carried out by collecting secondary patient data recorded in the form archive and the results of the histopathological examination of uterine cervical biopsy at the Anatomical Pathology Laboratory of Sanglah Hospital Denpasar in 2018 - 2019. The patient data collected were in the form of age, biopsy indications, and the degree of SIL. The samples collected in this study were 177 samples of SIL patients, with the most cases in the 41-50 years age category, namely 73 people (41.2%). The mean age of LSIL patients was 41.5 years and HSIL patients were 39.7 years. The findings of the previous abnormal pap smear results as an indication of a biopsy were found to be the most, namely 73 people (41.3%), and the highest degree of SIL was HSIL as many as 94 people (53.1%).

Keywords: precancerous lesions, cervix, SIL, Sanglah Hospital Denpasar
KARAKTERISTIK KLINIKO HISTOPATOLOGI NODUL TIROID DARI 1 JANUARI 2016 – 31 DESEMBER 2017 DI LABORATORIUM PATOLOGI ANATOMI FAKULTAS KEDOKTERAN UNIVERSITAS UDAYANA/ RSUP SANGLAH DENPASAR
Authors: Indriani Silvia Nuhyil , Dewi I Gusti Ayu Sri Mahendra , Sriwidyani Ni Putu , Ekawati Ni Putu
Published: August 2023

ABSTRAK

Latar Belakang: Kelainan nodul tiroid cukup banyak ditemukan di masyarakat. Insiden nodul tiroid meningkat seiring usianya bertambah dan wanita memiliki kejadian lebih tinggi dari laki-laki.

Tujuan: Penelitian ini bertujuan untuk mengetahui gambaran kliniko histopatologi  nodul tiroid dari 1 Januari 2016–31 Desember 2017 di Laboratorium Patologi Anatomi RSUP Sanglah Denpasar.

Metode: Penelitian ini merupakan penelitian deskriptif crosssectional retrospective yang diperoleh dari data rekam medis pasien di Laboratorium Patologi Anatomi RSUP Sanglah. Data dianalisis dengan menggunakan program SPSS versi 22.0.

Hasil: Didapatkan penderita nodul tiroid sebanyak 330 orang. Distribusi perempuan lebih banyak (84,5%) dibandingkan laki–laki (15,5%), dengan rentang umur terbanyak terjadi pada usia 41–50 tahun dan 51–60 tahun yaitu masing-masing 89 (27,0%) kasus. Diagnosis terbanyak adalah penderita non neoplastik sebanyak 206 (62,4%) kasus, dengan lateralisasi terbanyak  terjadi di seluruh bagian tiroid sebanyak 233 (70,6%) kasus.

Kesimpulan: kelainan nodul tiroid cenderung lebih banyak pada perempuan dengan usia 41-60 tahun, bersifat jinak dan terjadi pada seluruh lobus tiroid.

 

Kata kunci: Nodul tiroid, Kliniko histopatologi
The Description of Hormonal Risk Factors of Breast Cancer Patients in RSUP Dr. Mohammad Hoesin Palembang
Authors: Hutahaean Arekcsueng , Qodir Nur , Fadilah Mariatul , Umar Mulawan , Roflin Eddy
Published: August 2023

Breast cancer is a multifactorial disease. Most of the breast cancer risk factors are hormonal risk factors that associated with the length of exposure to estrogen hormone. This study is aimed to know the description of hormonal risk factors of breast cancer patients in RSUP Dr. Mohammad Hoesin Palembang. This study is a descriptive-observational study with cross-sectional design. Samples in this study are medical records of breast cancer patients in RSUP Dr. Mohammad Hoesin Palembang during January 2019 – August 2020 that meet the inclusion and exclusion criteria. In this study, 97 breast cancer patients were included as participant. Most of the participants had menarche at the age of 12 – 14 (72.2%), menopause at the age of 45 – 54 (38.1%), first pregnancy at the age of 20 – 29 (48.5%), parity  ? 3 times (46.4%), breastfed (76.3%), used hormonal contraception (71.1%), not used any menopausal hormone (96.9%), not consumed alcohol (100%) and normal nutritional status (56.7%).
TREATMENT OF GIARDIASIS IN DOMESTIC CATS
Authors: Aisya Sutadisastra Nisha , Kayati Widyastuti Sri , Soma I Gede
Published: August 2023

Giardiasis is a disease caused by Giardia sp. a protozoan which infects the small intestine causing non-specific diarrhea in humans and other mammals. This article aims to help readers find out the causes of giardiasis in cats, and how to treat cases of giardiasis in cats. A 1-year-old queen named Qaqa that weighs 2.15 kg had suffered diarrhea for a month. Previously, the cat had been given an antidiarrheal drug called Guanistrep which helped in reducing the frequency of diarrhea but after finishing the drug, the diarrhea recurred. Clinical examination showed the cat experience inflammation on the anus, slow capillary refill time (CRT), and increased body temperature but there was no indication that the cat was dehydrated. Examination of the feces found the presence of the protozoa Giardia sp. The Hematological examination of the cat indicates leukocytosis, monocytosis, and granulocytosis. The cat was diagnosed with Giardiasis. The therapy given is the administration of Metronidazole, Nutria Gel Plus, and Guanistrep which all were given orally. Two weeks after the administration of the medication, the frequency of the cat's defecation decreased and the feces had a solid consistency. To avoid Giardia sp. infection, owners need to be educated on how to properly care for their cat’s by providing drinking water with mineral water and limiting the interaction with wild animals, as well as maintaining the cleanliness of the cat's residence, especially where the cat eats and drinks.
Дерево в сакральном пространстве удмуртов и его охрана
Authors: Михайлова Марина Алексеевна
Published: August 2023

В статье рассматривается вопрос сакрализации образа дерева в дохристианских представлениях удмуртов, коренного финно-угорского народа, проживающего в междуречье Камы и Вятки (Удмуртская Республика, далее – УР). Приводится типология объектов поклонения из дерева или составных его частей. Определены следующие типы: капища, посвященные хозяевам Дикой Природы, священные рощи, Куала, ритуальные предметы, одиноко стоящие деревья. Рассмотрен вопрос охраны выделенных объектов культа: некоторые из них имеют статус объектов культурного наследия в качестве достопримечательных мест, территория других – совпадает с территорией памятников археологии, третьи – составляют музейные коллекции и находятся в государственной собственности, еще часть – сохраняет культовую роль и находится под контролем участников молений, которые поддерживают целостность памятника системами ограничений и табу. Отмечается также использование некоторых образов в качестве туристических и арт-объектов.
A study into the relationship between the type of Japanese candlesticks of a nationally significant exchange-traded asset and investor sentiment in the national financial market
Authors: BOGATYREV Semen Yu. , NIKONOVA Irina A. , ZATEVAKHINA Anna V.
Published: August 2023

Subject. This article examines the relationship between the type of Japanese candlesticks of a nationally significant exchange-traded asset and investor sentiment in the national financial market. Objectives. The article aims to determine the relationship between the type of Japanese candlesticks for a nationally significant asset traded on the national stock exchange and the sentiments of financial market participants. Methods. For the study, we used the methods of induction and deduction, statistical methods for processing the results of observations, and the method of physiognomy in determining the emotions of persons making investment decisions. Results. The article determines the type of Japanese candlesticks for a nationally significant asset traded on the national stock exchange and the sentiments of financial market participants. Conclusions. When taking into account new indicators, the analyst has the means to bring the forecast result closer to real conditions, when, in addition to traditional indicators, combinations of technical analysis tools and psychological indicators in the markets give a new interpretation of the events taking place there. This improves the quality of analytical work and its results. The results of the research described in the article can be applied in the work of a market analyst. The use of new indicators complements and expands the classic analytical tools, improves the quality of market forecasts.
Evaluation of The Effects ofAmlodipine Therapy on Blood Pressure and KidneyFunction among Hypertensive Patients in Mosul City
Authors: llamo Mahmood Isam
Published: August 2023

The present snrdy was mnducted to evaluate fte effect of amlodipine on blmd p€ssurc and kidney function inpatients in Mosul clb,. Thirty patients participated in ftis S.rdy ( 14 female ard 16 nrale )Arnlodipine was administercd for a period of 8 weeks in doses of 5 to l0 mg once daily. Antlripentensive efficacy wasassesd by measurement of blood pressure by standand mercury sphygmomanometer before and afur rcdnent . Bloodsampleswercobtained fiomeachpatientbeforeardafurteatnentand tlreobtainedserawereanalpodforruralpaarnetasvririch they all measr"ned in serum by using mlorimetic and en4anaic mehod. Credinine cleararce was calculded bywingthe Cockoft and Gault ecluation.The resulb of the study showd that anlodipine drerqpy lead tl a sigrificant reduction in blood pressue tllrugfrout thestudy and about 5fflo ofthe patien8 exhibit BP reduction tc notmal values afur drerapy. CreAinine clearance was significarflyincreased afur the end of the sudy . All other renal parameten including urea , credinine, sodilnn and potassiumconcentdions showed a sigrificant reductions. It was concluded that therapy with arnlodipine car be useful ard effediveflrcmpyinhpefiensivepaientswith deterioratdkidneysfi.lictionin oncedailydosage.
Evaluation of serum lipid in diabetic patients on differenttypes of treatment
Authors: S. Saeed Hosam aldeen , S. Mohammed Taha , E. Kasem Samit
Published: August 2023

Diabetes mellitus is chronic metabolic disorder which causes many complications. These are subdivided into microvascular complication affecting retina, kidney and peripheral nerves and macrovascular complications (atherosclerosis) affecting the major arterial systems including coronary arteries. Abnormal lipid metabolism is common in DM and it play an important role in the macrovascular complications. In this case control study 150 diabetic patients on different regimens of treatment were investigated for hyperlipidemia and compared to each other and to 50 apparently healthy control. Comparison of each group of diabetic patients with the control group was as follow; regarding total cholesterol there was no significant difference, higlyceride was significantly higher in group 2 (mixed insulin and oral hypoglycemic therapy), and group 3 (oral hypoglycemic drugs therapy) (P<0.001) in comparison with control group, while in group I (only insulin therapy) it was lower than the control group, but the difference was siatistically not significant, HDL was significantly lower in all groups in comparison with control group and the least value of HDL was found in group 3 (P<0.001). Regarding LDL there was no significant difference in comparison with the control group, while VLDL was higher in group 2 and 3 than the control group and the difference was significant (P<0.001). Comparison of the measured parameters among three groups of diabetic patients was as follow; regarding total cholesterol and LDL there was no significant difference among these three groups. Triglycerides and VLDL were significantly lower in group 1 (P<0.001), while HDL was significantly lower in group 3 (P< 0.001). Cholesterol, triglycerides and VLDL were significantly higher in females in group 2 (P<0.05). Regarding HDL and LDL no significant difference was found between males and females. In group I triglyceride was higher in those with 5 - l0 years treatment, while in group 2 & 3 there was no significant difference in measured parameters regarding the duration of treatment
A survey of flexible bronchoscopy practice at Kenyatta National Hospital, Kenya
Authors: Bashir Abdiweli M. , Mecha Jared O. , Achieng Loice , Owuor Andrew
Published: August 2023

Objectives:

Flexible bronchoscopy (FB) is an essential diagnostic and therapeutic tool for managing respiratory diseases, and an audit of its practice is important; it enhances standardization of practice and improves outcomes and patient safety. This study aimed to describe the FB practice at Kenyatta National Hospital (KNH) regarding indications, peri-procedure practice, gross and histologic findings, and safety.

Materials and Methods:

This study was a quantitative and retrospective chart review of files of 282 patients who underwent flexible bronchoscopies over 5 years in KNH.

Results:

We reviewed 282 flexible bronchoscopies done between January 2016 and December 2020. There was a significant documentation gap (22%); 54 out of the 282 cases audited had incomplete documentation. The male-to-female ratio was 1:1, with a median age of 51 years. Most (58.2%) of the patients were residents of counties outside Nairobi. Despite a lack of evidence for routine evaluation, we noted significant rates (75.9%) of routine laboratory evaluations (International normalized ratio (INR), platelet count). The most common indication of bronchoscopy was the evaluation of a lung mass (100) 35.7%, pulmonary infiltrate 53 (18.9%), and assessment for interstitial lung disease 39 (13.9%). The most common gross bronchoscopic findings were visible tumors at 38.5% (107) and normal endoscopic findings at 29.5% (82). The practice was safe, with a complication rate of 3.2%. The most common diagnostic outcome was lung cancer (40.1%), with adenocarcinoma being the most common (45.1%) histologic subtype. The diagnostic yield for malignancy where there was a visible tumor was 87.2%.

Conclusion:

Our study showed that FB practice at KNH is safe and provides a good diagnostic yield, but a significant documentation gap and record keeping exist. Adenocarcinoma was the most predominant lung cancer histologic subtype among the mostly non-smoker population.
Data-driven Discovery of Potent Small Molecule Ice Recrystallisation Inhibitors
Authors: Warren Matthew T. , Biggs Caroline I. , Bissoyi Akalabya , Gibson Matthew I. , Sosso Gabriele C.
Published: August 2023

Controlling the formation and growth of ice is essential to successfully cryopreserve cells, tissues and biologics for research or clinical use. Current programmes to identify materials capable of modulating ice growth are guided solely by iterative changes and human intuition, with a major focus on macromolecules (proteins or polymers). This process is fundamentally constrained by a poor understanding of the mechanisms and underlying structure-activity relationships. Here, we overcome this barrier by constructing machine learning models capable of pre- dicting the ice growth inhibition activity of small molecules. Due to current limitations in experimental throughput, we leverage ensemble models which combine state-of-the-art descriptors with domain-specific features derived from molecular simulations. When applied to virtually screen a commercial compound library, these models successfully predicted novel ice recrystallisation inhibitors that are experimentally verified to function at low millimolar concentrations. This data-driven approach will enable the discovery of new cryoprotectants to address the rapidly growing clinical and biotechnological cold-chain demands.
Metal-Organic Framework Supercapacitors: Challenges and Opportunities
Authors: Shin Seung-Jae , Gittins Jamie , Balhatchet Chloe , Walsh Aron , Forse Alexander
Published: August 2023

Supercapacitors offer superior energy storage capabilities than traditional capacitors, making them useful for applications such as electric vehicles and rapid large-scale energy storage. The energy storage performance of these devices relies on electrical double-layer capacitance and/or pseudo-capacitance from rapid reversible redox reactions. Metal-organic frameworks (MOFs) have recently emerged as a new class of electrode materials with promising supercapacitor performances and capacitances that exceed those of traditional materials. However, our comparison of the supercapacitor performance of a porous carbon and a state-of-the-art MOF highlights a number of challenges for MOF supercapacitors, including low potential windows, limited cycle lifetimes, and poor rate performances. We propose that the well-defined and tuneable chemical structures of MOFs present a number of avenues for improving supercapacitor performance. We also discuss recent experimental and theoretical work on charging mechanisms in MOF-based supercapacitors, and find a need for more studies that elucidate the charge storage and degradation mechanisms. Ultimately, a deeper understanding will lead to design principles for realising improved supercapacitor energy storage devices.
Reflexiones y retos educativos como respuesta a un contexto cambiante
Authors: Álvarez Cano Alejandro , Mesa Franco Ana Lucía , Lenis Román Carlos Andrés , Velásquez Camargo Claudia Irene , Hincapié Gómez David , Cumaco Perdomo Diana Alexandra , Gayón Rincón Diego Armando , Ortiz Velosa Eliana Marcela , Simanca Herrera Fredys Alberto , Meza Salcedo Guillermo , Rodríguez Núñez Grisel , Valbuena Reinoso Ingry Paola , Pérez Páez Jenny Alejandra , Angarita Julián Andrés , Mesa Leidy Ximena , García González María Camila , Rodríguez Villamizar Mary Janeth , Bonilla Suárez Myriam Yaneth , Cáceres Delgado Morela , Merchán Rangel Nancy , Mora Cifuentes Paola Milena , Manuel Negrón Pedro , Quintana Marín Sofía , Orozco Gómez William , Salas Picón Wilson Miguel , Martínez Díaz Yesika Paola , Castrillón Jaimes Yusbely Cecilia
Published: August 2023

Pensar en la educación implica reflexionar sobre las teorías que orientan las prácticas pedagógicas, tanto como sobre la práctica en sí misma, y la forma en la que esta se adapta a los distintos contextos y características sociales propias de cada época y momento de la historia. La Corporación Universitaria Minuto de Dios, Uniminuto, comprometida con la difusión social del conocimiento para la transformación de la educación en el país, realiza en su sede Bello el Congreso Internacional de Educación y Pedagogía “Retos educativos como respuesta a un contexto cambiante”, con el objetivo de intercambiar saberes y mediante estos, construir y compartir conocimientos relacionados con la actualidad pedagógica. A su vez, en pos de reconocer experiencias significativas que se desarrollan en el contexto mundial y que sirven como referentes para la implementación de nuevas tecnologías y estrategias que enriquezcan el campo educativo de manera contundente. En su trayectoria el evento ha contado con importantes invitados de distintos países, quienes han formulado propuestas para el mejoramiento continuo de la práctica pedagógica y han compartido con los asistentes conocimientos y experiencias vividas en contextos variados.
Creep of concrete incorporated with marble powder
Authors: Syed Afzal Basha , B. Jayarami Reddy
Published: August 2023

This study presents an experimental investigation of the mechanical properties of concrete incorporating Kadapa Marble Powder (KMP) as an additional cementitious material. It focuses on varying the content of KMP (ranging from 0% to 15% by weight of cement) and conducting tests on compressive strength, modulus of elasticity, and creep. The replacement of cement with KMP led to improvements in the compressive strength and modulus of elasticity, and the incorporation of KMP contributed to a reduction in the creep phenomenon of concrete over time. The beneficial effects of KMP can be attributed to its ability to react with calcium hydroxide generated during cement hydration. This reaction results in the production of additional calcium silicate hydrate, which fills voids and large pores within the concrete matrix. As a result, the porosity associated with the capillary pores and voids decreased. This observation was supported by the examination of the microstructure of hardened concrete using scanning electron microscope techniques. The presence of KMP enhanced cement hydration and contributed to a reduction in the porosity associated with the gel pores. This was attributed to the release of absorbed water retained in the small pores of the KMP particles. This study highlighted the potential of incorporating KMP as a beneficial cementitious material for concrete production. These findings suggest that KMP can enhance the mechanical properties of concrete, including the compressive strength and modulus of elasticity, while mitigating the creep phenomenon. The analysis also provides insights into the microstructural changes that occur in concrete due to the inclusion of the KMP.
Attitude of post graduate students towards online education
Authors: Nilima Mondal , Santosh Kumar Behera
Published: August 2023

The current study attempted to determine the attitude of postgraduate students in the Paschim Bardhaman District of West Bengal, India, towards online education. The survey method was employed, and a total of 155 postgraduate students from Kazi Nazrul University, West Bengal, were taken as representative samples of the population as a whole. The selection of postgraduate students was done using a simple random sampling technique. An attitude scale was utilized for gathering the data. Percentage, mean, SD, t-test, and ANOVA were used to analyze the data. According to the report, postgraduate students in West Bengal's Paschim Bardhaman District have an average attitude towards online education. Additionally the study revealed that the attitude of postgraduate students towards online education did not differ significantly based on their gender, locality, semester, caste, and streams.
Carotenoids composition, antioxidant and antimicrobial capacities of Crocus
sativus L. stigma
Authors: Mohd Hatta F.A. , Othman R. , Mat Ali Q.A. , Mohd Hassan N. , Ramya R. , Wan Sulaiman W.S. , Mohd Latiff N.H. , Mohd Kashim M.I.A.
Published: August 2023

Carotenoid compounds are effective free-radical scavengers because they display a singlet
oxygen-quenching property and can trap peroxyl radicals. Many extracts derived from
natural sources consist of unique bioactive compounds. For example, hydrophilic
carotenoids, such as crocin, are present in saffron and possess antioxidant, anticancer, anti
-inflammatory and antimicrobial properties. Crocin is responsible for preventing and
curing many health issues. This study investigated the antioxidant and antimicrobial
properties of hydrophilic carotenoid (C50) molecules extracted from Crocus sativus L.
(saffron stigma) grown in different locations. These compounds were tested for their
antioxidant properties through 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay, while
antimicrobial activity was determined using disc diffusion method. Four carotenoid
compounds (i.e. crocin, crocetin, β-carotene and zeaxanthin) were detected from the three
saffron samples collected from various localities. High-performance liquid
chromatography (HPLC) analysis was carried out to determine the physical and chemical
properties of the carotenoid samples. The HPLC results indicated the presence of a single
crocin peak at 440 nm. The crocin concentration in Iranian saffron was higher
(11414.67±516.34 µg/g DW with 99.9% purity) than those in Turkish and Kashmiri
saffron. This finding suggested that location significantly affected crocin concentration as
well as carotenoid composition and content in saffron. Crocin molecules (100 µg/mL)
showed the highest antibacterial activity against Staphylococcus epidermidis, with a 6.0
mm inhibition zone. Hence, crocin molecules (500 µg/mL) were effective antioxidant
compounds as they showed 68% inhibition, with an IC50 value of 283.918±3.934 µg/mL.
In addition to being a biocolourant source, crocin may be used for its antioxidant and
antibacterial properties.
Antibacterial and antioxidant activities of ethanol extract of Artocarpus lacucha
Buch-Ham leaves
Authors: S. Panal , M. Mahatir , S. Denny , Nasri
Published: August 2023

Phytochemicals with antimicrobial and antioxidant properties have tremendous potential
in suppressing both plant and human diseases. Screening and identifying such
compounds from diverse plant species is the first step toward realizing they are
medicinal. Mobe plant (Artocarpus lacucha Buch-Ham.) is a species of Artocarpus from
the family Moraceae and contains a lot of phenolics (flavonoids and phenolic acid).
Flavonoids, phenolic acids, and phenolic derivatives are phenolic compounds derived
from plant flavonoids that can be used as antitumor, antibacterial, antifungal, anticancer,
and anti-inflammatory drugs. This study aimed to determine the antibacterial and
antioxidant activities, total flavonoid, and total phenolic content of Artocarpus lacucha
Buch-Ham leaves. The extract was prepared using ethanol with the reflux method. The
antibacterial activity was determined with the minimum inhibitor concentration method.
The concentration of 300 mg/mL up to 25 mg/mL can inhibit the growth of
Staphylococcus aureus, Staphylococcus epidermidis, Cutibacterium acnes, Pseudomonas
aeruginosa, the Minimum Inhibitory Concentration (MIC) itself is at the smallest
concentration that has been able to inhibit bacterial growth. The number of bacteria is <
10 colonies. The antioxidant activity was determined with the 1,1- diphenyl-2-
picrylhydrazyl (DPPH) method. Total flavonoid and total phenolic contents were
determined with colourimetric methods. Antioxidant activity from the DPPH assay
measured as IC50 value was 22.83±0.56 µg/mL. The extract contained high levels of
total phenolic (300.77±4.56 mg GAE/g) and total flavonoid (15.56±0.32 mg QE/g). The
results revealed that ethanol extract of Artocarpus lacucha Buch-Ham leaves has
antibacterial and antioxidant potential.
Light Almighty
Authors:   , Culling George
Published: August 2023

The city is built upon layers of history and is in a state of constant change and evolution. This thesis questions how can we intervene with the pre-existing and seemingly ordinary layers of the urban fabric? This design-led research begins with observations of the pre-existing context, a site located between busy Riddiford Street and quiet Gordon Place in Newtown, Wellington. The investigation iteratively evolves through analogue and digital modes, utilising a creative-based research methodology. The design outcome aims to preserve elements from the pre- existing architecture while proposing new interventions to create connections and open dialogues between the two streets through the visual opening of a pathway.

This thesis engages with a phenomenal understanding of architecture and uses this to propose a human-centred experience for a community gallery and studio space in the pre-existing building onsite. This thesis attempts to offer one solution that adaptively reuses a pre-existing architecture, attempting to balance the need for evolving spaces while acknowledging the character and memory intertwined with the layers of built form. This approach employs design to be resourceful, respecting the pre-existing layers of the city while offering a new evolution of this space.
Japanese Women Language Politeness in Communication Interview: Sociolinguistic Study
Authors: Arfianty Rani , Mubshirah Dara , Pujiono Mhd.
Published: August 2023

Abstract. This study aims to investigate and define Japanese women's language politeness in communication interviews. This study is descriptive, using a content analysis approach. This study collected Japanese women's words, phrases, and clauses from YouTube videos and used free-conversation listening and note-taking techniques to acquire data. The results showed three main types of Japanese woman’s polite language in communication interviews: teineigo, kenjougo, and sonkeigo. Sonkeigo is used when the speaker wishes to show respect for the other person and the person being discussed. In contrast, the phrase kenjyogo puts the speaker on a lesser level with the recipient. Teineigo is best described as a form of polite or formal speech. It is found that keigo is a method of Japanese women to express their politeness, etiquette and also emotional in the same time This finding also contributes to a greater understanding of social position and social status in Japanese society, as well as how Japanese women communicate to maintain their image in the eyes of others Keywords: Japanese Woman, Politeness Language, Communication Interview, Sociolinguistic
Rol de la mujer en la gestión de riesgos, instituciones públicas
Authors: Iñiguez Gloria Piedad , Durán Priscila Vanessa , Barragán Aroca Grey , Gavilanes Carina Alexandra , Del Rocío Uzuay Mirian
Published: August 2023

Hoy en día aún se sigue evidenciado que la igualdad de género y la participación de la mujer sigue siendo limitada en los diferentes ámbitos, pese a sus logros y avances que ellas han ido alcanzo gracias a su esfuerzo y perseverancia, considerando así en investigar el Rol de la mujer en la Gestión de Riesgos en las diferentes instituciones públicas del Casco Urbano del Cantón Guaranda. La Gestión de Riesgos en la actualidad juega un papel muy importante tanto en la sociedad como en las instituciones públicas y privadas, considerándose un eje transversal en la planificación del desarrollo, buscando garantizar el bienestar de toda la población y la conservación y protección de los bienes inmuebles ya sean de un patrimonio cultural o natural frente cualquier tipo de amenaza y riesgo de origen natural y antrópico.
Planteando así un enfoque de investigación cualitativo, mismo que ayudó a conocer y categorizar el rol de la mujer en la Gestión de Riesgos; el cual se lo realizo bajo la metodología Delphi y la teoría fundamentada en los datos que a través de la aplicación de encuestas, entrevistas y visitas in situ, se pudo identificar que aún en las instituciones públicas del casco urbano de Guaranda no existe una inserción de la temática de Gestión de Riesgos como corresponde en sus diferentes fases,  por ende la participación de la mujer es limitada pese a su gran aporte que brinda para el desarrollo y como no en el área de Gestión de Riesgos.
Impacto del Covid-19 en la ansiedad de jóvenes. Vinchoa 2022
Authors: Mas Camacho María Rosa , Rea Guamán Mery Rocío , Amador Torrecilla Anicel Amador Torrecilla , Morejón Mishell Alexandra
Published: August 2023

Han sido los adolescentes y adultos mayores los grupos poblacionales más vulnerables en la pandemia por el COVID-19 respecto a la salud mental. Es objetivo del trabajo que se expone identificar la ansiedad en la población adulto joven de 18–35 años de la parroquia de Vinchoa, ciudad Guaranda, provincia de Bolívar, Ecuador por la situación de salud vivido, lo que trajo el incremento de manifestaciones de estrés, depresión y problemas psicosociales presentados a nivel individual, familiar y social por motivo del confinamiento durante la pandemia. Constituye un estudio cuantitativo de corte trasversal desarrollado durante diciembre de 2021 a febrero del 2022, la muestra estuvo conformada por 203 personas que cumplieron con el requisito de edad además de su predisposición de participación declarada de manera explícita; se aplica el test IDARE como instrumento de medición para la ansiedad. Se desarrolla el programa "Alienta tu mente a un buen mañana" el cual consistió en la realización de visitas a cada comunidad, acompañados por el médico del centro de salud, donde se identifican las preferencias de actividades para cada comunidad, siendo estas deportivas y de creación artesanal predominantemente, sobre esta base y los resultados obtenidos del test referido se realizaron charlas y actividades deportivas como formas de esparcimiento; el programa concluye con la realización de una casa abierta en el centro de salud de la parroquia donde los participantes exponen sus productos artesanales resultado de su creación en colectivo. Se identifica el 68,47% de la muestra del estudio con un estado de ansiedad alto.
innovación invertida como elemento estratégico frugal en la enseñanza educativa
Authors: Núñez Michuy Carlos Manuel , Veloz Segura Verónica Teresa , Agualongo Chela Luis Marcial , Tamami Pachala Jorge Wilson
Published: August 2023

La innovación invertida es un enfoque pedagógico que puede ser empleada tanto en escenarios interactivos (tecnológicos) como presenciales, y se utiliza para desplegar actividades de aprendizaje grupales y personalizado. Cuando se integra a procesos estratégicos frugales, se obtienen transformaciones relacionadas con los cambios de mentalidad, consolidación de conocimientos y mejoras en cuanto al rendimiento académico. El objetivo del trabajo es mejorar el rendimiento de los estudiantes y a su vez la calidad educativa, aportando así al cumplimiento de los ODS planteados por la UNESCO. La metodología es de tipo descriptiva con un enfoque mixto. Las técnicas utilizadas para la recolección de datos fueron la encuesta con su instrumento cuestionario de preguntas ejecutadas de manera online mediante Google Forms. También se practicaron entrevistas a docentes para obtener mayor profundidad analítica. Los resultados denotan que el escenario educativo el cual las herramientas tecnológicas vinieron a marcar la metamorfosis a raíz de la llegada de la pandemia, es propicio incursionar y fusionar elementos digitales en concordancia con aquellos resultados que hasta ahora y, basados en la experiencia del docente, han sido satisfactorio dentro del proceso de aprendizaje escolar. Las conclusiones destacan la importancia de profundizar en las bondades que ofrece la frugalidad, cuyo principal objetivo radica en realizar acciones de reingeniería para identificar y desechar lo que no agregue valor a los procesos.
Relación entre la planeación estratégica y la creación de ventaja competitiva sostenible en emprendimientos de la economía popular y solidaria en el Ecuador
Authors: Sánchez Montero Ivanna Karina
Published: August 2023

El propósito de la investigación es conocer la correlación existente entre las variables planeación estratégica y creación de ventaja competitiva sostenible, dentro de las organizaciones de la economía popular y solidaria, asentadas en las zonas de planificación 2 y 3 del Ecuador. Para el diseño y metodología, se utilizó la investigación cuantitativa – correlacional, a través de una encuesta aplicada a 987 asociados – emprendedores, de cinco asociaciones pertenecientes al sector no financiero de esta economía. El análisis demuestra que el desarrollo de una adecuada planeación estratégica influye de manera significativa en la creación de ventajas competitivas, es decir, las distintas estrategias utilizadas en los emprendimientos ayudan a ser sostenibles en el tiempo