bluuebunny/crossref_metadata_2025 huggingface dataset:
Penambahan Fitur Buku Tamu pada Aplikasi Open Source Slims di Perpustakaan STMIK “AMIK BANDUNG”
Authors: Pajaransyah Rhendy , Darmanto Tedjo , Saputra Dany Eka
Published: September 2020

Saat ini pengunjung perpustakaan STMIK “AMIKBANDUNG” mengisi bukutamu dengan cara mengetik data diri secara lengkap baik sebagai member maupun non member. Dan cara tersebut sangat rentan terhadap manipulasi data, sedangkan validasi pengunjung perpustakaan sangat diperlukan untuk rekapituasi laporan pengunjung secara berkala dan pada saat dilakukan akreditasi perpustakaan. Sistem pencatatan pengunjung perpustakaan yang saat ini ada di perpustakaan STMIK “AMIKBANDUNG” memerlukan permbaharuan. Karena dampak dari pembaharuan yang dilakukan sangat baik bagi perpustakaan kampus. Maka dari itu, Penulis melakukan penambahan fitur pada aplikasi open source SLiMS. Desain bukutamu yang nantinya akan dibagi menjadi dua tipe yaitu member dan non member. Mahasiswa yang masuk kedalam kategori member hanya memasukan ID member kedalam form pencatatan buku tamu. Dan untuk non member, tetap mengisi data diri nya secara lengkap. Sehingga memudahkan juga petugas perpustakaan untuk melakukan rekapitulasi pengunjung perpustakaan kampus.
The Relationship between Body Temperature and Egg Production Determined by a Thermal Camera in Laying Hens
Authors: YUSUF Abdirizak Mohamud , LAÇİN Ekrem
Published: September 2020

This study was carried out to investigate the culling of low-producing hens from a laying flock by objective methods. A total of 16 of two commercial laying hybrids (Lohmann White and Lohmann Brown) at 60 weeks of age, were used in this study. The body temperature of the chickens used during the trial period was obtained from the head and foot regions with the help of a thermal camera and the egg production has been associated. Considering the egg production, differences between hybrids were statistically significant (P < 0.001). In terms of temperature values taken from the morning foot section, differences between white and brown laying hybrids were not statistically significant (P > 0.05) during the experimental period. Considering the temperature values taken in the afternoon, differences between the hybrids were statistically significant (P < 0.01). ROC analysis has been used to determine the relationship between egg production and body temperature. According to the result of the test, the critical point between the temperature of the morning (head region) and the egg yield was determined. Accordingly, chickens having a temperature higher than 38.3 ° C were laying more eggs than those having a temperature lower than 38.3 ° C. The trial lasted 16 weeks and its conclusion, we can infer from the experiment conducted during this study that the temperature value taken from the head section in the morning by the thermal camera can be used to identify the low producing hens in laying flocks.
Justification of technical parameters of an ultrasonic device for improvement of meat salting efficiency
Authors: Krasnikova Ekaterina Sergeevna , Morgunova Natalya Lvovna , Rudik Phelix Yakovlevich , Krasnikov Aleksandr Vladimirovich , Semilet Nikita Andreevich
Published: September 2020

The results of a study of the effect of wet ultrasonic lamb meat salting on the muscle tissue microstructure are presented, and the technical parameters of the ultrasonic device are justified. It has been established that significant destruction and swelling of muscle fibers, local destruction of the sarcolemma with its pronounced rugosity are observed at ultrasonic salting with a frequency of 35 kHz, the cross-striation is poorly expressed, the tissue structure is disturbed. An ultrasonic salting with a frequency of 26 kHz was accompanied an increase in the number of transverse microcracks and crevices, loosening of muscle fibers, the formation of cavities between them while retention of the tissue structure, which contributes to the appearance of a brine between muscle fibers and accelerates its penetration into the fiber. It allows us to recommend ultrasound at a frequency of 26 kHz for cavitation activation of the brine to intensify the technological process of lamb meat salting.
Variability of valuable features of spring soft wheat samples of the VIR collection in arid conditions of the Astrakhan region
Authors: Naumova Nina Alekseevna
Published: September 2020

During the period of 2016-2018, 200 samples of spring soft wheat from the VIR collection, of different ecological and geographical origin in the conditions of rain-fed agriculture in the Astrakhan region, were studied. A high level of variability in the weight of grain from the ear and its lake level, plant height and productive bushiness, grain yield in the conditions of this area was determined. Selected samples-with high adaptive capacity, precocity and high productivity-will be recommended for further selection work.
Ways to improve cleaning technology and post-harvest processing of soybeans
Authors: Belyshkina Marina Evgenievna , Starostin Ivan Alexandrovich , Zagoruyko Mikhail Gennadevich
Published: September 2020

The article discusses the main causes of soybean crop losses, which can reach 25–30%. Most often, a high cut of the harvester's header, significant crushing and injury during harvesting, and violation of the post-harvest processing technology lead to losses and a decrease in the quality of commercial grain and seeds. The purpose of the research was to assess the impact of various factors on the amount of crop losses and develop recommendations for optimizing technological operations during harvesting and post-harvest processing of soybeans, compliance with which will ensure the minimization of quantitative losses and quality indicators of the crop. For soybean harvesting, it is recommended to use combines with hybrid or rotary threshing systems, which ensure careful cleaning and minimize output losses. Combines are equipped with reapers with a flexible cutting device, which, given the uneven terrain, provide a cut height of 2.5 cm. Primary cleaning of the grain heap should be performed immediately with subsequent drying: commercial grain to a humidity of 7–12% at the heating temperature of the coolant no more than 60°C, seeds to a conditioned humidity of 14% at the heating temperature of the coolant 35–40°C.
Economic evaluation of the effectiveness of soybeans growing with the application of fertilizers and biological products on ordinary chernozem under irrigation conditions
Authors: Shabaldas Olga Georgievna , Pimonov Konstantin Igorevich, , Solodovnikov Anatoliy  Petrovich , Vaytsekhovskaya Svetlana Sergeevna
Published: September 2020

The possibilities of increasing the productivity of soybeans grown on irrigation after application of mineral fertilizers and biological nitrogen in the steppe zone of the Central Ciscaucasia have been studied. It was found that, on average, over 3 years of research, the highest yield in the experiment was when growing the mid-season variety Selecta 302 with the introduction of ammophos in doses of N12P52 and N24P104 in combination with pre-sowing inoculation of seeds with rhizotorfin - 2.68 –2.74 t / ha, which is more than in standard variant (Vilana variety) by 0.11-0.12 t / ha. Compared to the control (without fertilizers and rhizotorfin), the increase was 0.21–0.27 t / ha, or 8.5–10.9%. It is economically feasible to grow the soybean variety Select 302 on irrigation with the application of mineral fertilizers at a dose of N12P52 and pre-sowing inoculation of seeds with rhizotorfin. The profitability was 68.8%.
Influence of the use of feed additives from local resources in diets on the digestibility of nutrients of Simmental cows in Yakutia
Authors: Borisova Paraskovia Prokopyevna , Nikolaeva Nataliya Afanasyevna , Alekseeva Nurgustana Mikhailovna
Published: September 2020

The article presents the results of experience in the application of feed additives from local resources in the diets of cows. As a result of the study, the positive effect of using feed additives from local resources in the diets of cows on the digestibility and assimilation of nutrients was proved. The digestibility of cow nutrients was higher in cows of the 2nd experimental group of the formula of feed additives No. 2. Thus, the cows of the 2nd experimental group, who received the recipe of feed additives No. 2 as part of the diet, better digested “raw” protein, fat, and fiber, which served as an additional source of energy for increasing milk productivity. The improvement in the digestibility of most nutrients in the diet is explained by the fact that protein-vitamin-mineral feed additives had a stimulating effect on the state of metabolic processes and the health of animals in general.
Percepción del color azul en escolares mediante un software desarrollado ad hoc
Authors: Valera-Mota Myrna Miriam , Bernal-Hernández Jorge , Guzmán-Noriega Mariana , Díaz-Uribe José Rufino
Published: September 2020

Objetivo. Determinar la percepción del color azul en niños. Métodos. Se creó un software que muestra tres estímulos azules: 430, 450 y 470 nm. Analizando mediante ANOVA: longitud/lateralidad ocular y edad/ sexo. Resultados. Mayores desviaciones en percepciones de 430 y 450 nm en edades de 6-8. En 450 nm las edades de 9-11 mostraron mayor desviación en ojo derecho, mientras que en los 470 nm se observaron mayores desviaciones en ojo izquierdo. Conclusiones. Las longitudes de onda que percibe el ojo humano entre 6 y 11 años de edad no difieren respecto al sexo, aunque imprecisa dependiendo de la LO percibida, la lateralidad y edad.
THE IMPACTS OF THE SPECIAL REGIONAL POLICY TO THE LOCAL GOVERNMENT ENFORCEMENT IN SOUTHERN THAILAND (CASE STUDY AT THE REPEL DISTRICT, KRONGPINANG, THAILAND)
Authors: Tehtae Sareef , Eby Hara Abubakar , Puspitaningtyas Zarah
Published: September 2020

Special territory policy has been using in the Southern Thailand is a central government’s policy (Bangkok) in terms of giving absolute authority to the military, to resolve the conflicts in southern Thailand. The policy includes three matters: 1) Martial law of 2547 (the regulations in state of emergency in the 2004); 2) the Emergency Decree 2548 PO-Ro-Ko (Security rules in state of emergency); 3) Internal Security Act in the 2551 PO – RO – BO (the rule in terms of internal security implementation of 2008). This paper aimed to analyzing the impacts of special regional policies on local governance in southern Thailand (case study in Repel district, Krongpinang, Thailand. This research used descriptive qualitative methodology.  based on research results, can be concluded that the impacts of the implementation of special regional policy; 1) the functional disappearance of local government; 2) local government was depressed by military system; 3) society harmonization to local government (village head) decreased.
Low-Cost Prosthesis for People with Transradial Amputations
Authors: Jaber Hneen Mahdi , Mohammed Mohammed A. , Abd al-Sahib Nabel Kadhim
Published: September 2020

Prosthetic is an artificial tool that replaces part of the human frame absent because of ailment, damage, or distortion. The current activities in Iraq draw interest to the upper limb discipline because of the growth in variety of amputees and. It is necessary to do extensive researches in this subject to help lessen the struggling of patients. This paper describes the design and development of low-cost prosthesis for people with transradial amputations. The presented design involves a hand with five fingers moving by means of a gear box mechanism. The design of this artificial hand allows five degrees of freedom(5DOF), one degree of freedom for each finger. The artificial hand works by an actuation system (6V) Polou motor with gear ratio equal to 50:1 due to its compactness and cheapness. The designed hand was manufactured by a 3D printing process using polylacticacid material (PLA). Some experimental were accomplished using the designed hand for gripping objects. Initially the EMG signal was recorded when the muscle contracted in one second, two seconds, three seconds. The synthetic hand was able to produce range of gesture and grasping moves separately just like the actual hand by using KNN classification which are complete hand Pinch, fist, and jack chuck.  The simulation of the fingers movements was achieved using ANSYS software to analysis the movement (pinch, fist, and jack chuck), obtain bested of stress influencer at each finger, and maximum deformation at each movement.
PENILAIAN KELAYAKAN EKOWISATA KARST CIBADAK DI KECAMATAN CIAMPEA KABUPATEN BOGOR
Authors: Hasibuan Ratna Sari , Cita Ken Dara
Published: September 2020

Kawasan Karst Cibadak perlu dilakukan penilaian kelayakan ekowisata untuk mengetahui apakah kawasan ini layak dikembangkan atau tidak. Tujuan penelitian adalah menilai kelayakan ekowisata Karst Cibadak terutama area eksokarst yang ada di Desa Cibadak. Metode penelitian adalah deskriptif dengan menggunakan analisa penskoringan Daya Tarik Wisata Alam (DTWA). Hasil penelitian meunjukkan bahwa kawasan Karst Cibadak layak dikembangkan sebagai daerah tujuan ekowisata dengan nilai 77,87%. Daya tarik wisata alam di kawasan Karst Cibadak antara lain: wisata tracking, wisata edukasi dan camping ground. Daya Tarik wisata budaya di kawasan Karst Cibadak yaitu adanya bekas peninggalan Kerajaan Siliwangi. Kawasan ini perlu ditambahkan atraksi wisata lain seperti pengamatan flora dan fauna karst, outbond, penelusuran gua, pengamatan fauna gua agar meningkatkan nilai kelayakan Karst Cibadak. 

 

Kata kunci: daya tarik wisata alam, karst Cibadak,  kelayakan
KEANEKARAGAMAN TUMBUHAN OBAT MASYARAKAT DI HUTAN TALANG RENCONG DESA PULAU SANGKAR, KABUPATEN KERINCI, JAMBI
Authors: Adriadi Ade , Nursanti Nursanti , Puspitasari Rike
Published: September 2020

Indonesia has approximately 30,000 species of medicinal plants based on the richness of the flora. Indonesia has the great potential to develop herbal products that are equivalent to modern medicine. The modern treatment has not been reachable by the whole community in Indonesia, only about 25% affordable and the rest are not yet affordable. The role of traditional medicine recipes become much helpful especially for people living in remote areas with minimal access. The research was conducted in April-May 2019 at Talang Rencong Traditional forest, Pulau Cage Village, Kerinci Regency, Jambi. The sample area of research was 1 Ha, or 5% of total area. The methods used in this research were participatory exploration and observation, data collection was conducted by tracing indigenous forests accompanied by local communities (Data is analyzed from any species found during research). The research in the indigenous forest Talang Rencong village Pulau Cage, Kerinci Regency, Jambi acquired 23 familia and 39 species of medicinal plants used. How to use from the herbs are divided into 25 species of medicinal plants that use drinkable, 6 species of medicinal plants are applied or pasted, 4 species of herbs are directly consumed, 1 species of medicinal plants is used to be washed, 2 species of medicinal plants used to be dipped in the eyes and 1 type of medicinal plants that use the input into perforated teeth The benefits of such medicinal plants are as breast cancer medicine, relieves itching for children, nail health remedy, uric acid medecine, removal bruising, uterine watering, appetite enhancer, diarrhea, toothache medications, jaundice medications, cough medicines, shortness of breath medication for infants, deep heat medications, reducing blood sugar levels, paralysis medications, lowering cholesterol, and medication for postnatal blood and uric acid.

 Keywords: ethnobotany, medicinal plants, Rencong customary forest
Producción, crecimiento y calidad nutrimental del garbanzo en función del nitrógeno y fósforo
Authors: Apáez Barrios Maricela , Escalante Estrada José Alberto Salvador , Apáez Barrios Patricio , Alvarez Hernandez Juan Carlos
Published: September 2020

El garbanzo es rico en proteínas y carbohidratos, de importancia en la alimentación humana. Actualmente su rendimiento es limitado por falta de recomendaciones sobre la fertilización de nitrógeno (N) y fósforo (P). En este sentido, estos nutrimentos pueden contribuir a incrementar el rendimiento, acelerar el crecimiento, acumulación de biomasa y la calidad nutrimental. Los objetivos del estudio fueron evaluar el efecto de N y P sobre los días a ocurrencia de fases fenológicas, rendimiento de grano, crecimiento del cultivo, acumulación de biomasa y calidad nutrimental del garbanzo. Bajo condiciones de lluvia estacional en Huitzuco, Guerrero., México, se sembró garbanzo el 01 de junio de 2017, con tres niveles de N (0, 75 y 150 kg N ha-1) y P (0, 75 y 150 kg N ha-1); respectivamente). Durante el estudio las temperaturas máximas y mínimas oscilaron entre 31 a 35 °C y 16 a 18 °C respectivamente, con precipitación pluvial de 806 mm. La ocurrencia de las etapas fenológicas fue similar entre tratamientos, así la emergencia ocurrió 10 días después de la siembra (dds), la floración a 55 dds y a 120 dds la madurez fisiológica. Con 150 kg de N y P ha-1 (N150-P150) se presentó el mayor rendimiento de grano (580 g m-2), la mayor acumulación de biomasa total (490 g m-2), además el grano fue al cual se le modificó la cantidad de biomasa acumulada con un incremento de 3% en relación con los tratamientos sin N. La tasa media de crecimiento del cultivo fue mayor con aplicaciones de N, mientras que con P la tendencia fue similar. Por otra parte, el nutrimento que influyó en mayor medida a interceptar radiación fue el N. Con N y P se incrementó la concentración de proteínas y carbohidratos solubles.
Examination of Material Compatibilities with Ionized and Vaporized Hydrogen Peroxide Decontamination
Authors: Kimura Tohru , Yahata Hiroyuki , Uchiyama Yoshimichi
Published: September 2020

Hydrogen peroxide (HP) decontamination is effective for a wide spectrum of pathogenic microorganisms. However, exposure to HP causes deleterious effects on some materials. The purpose of this study was to examine material compatibilities with ionized and vaporized hydrogen peroxide
(iHP and VHP). With regard to iHP, 24 kinds of materials were exposed up to 100 cycles to iHP. The tested materials included plastics, metals, woods and plated or coated goods. The procedure of iHP decontamination was as following: gas time (11 min), dwell time (15 min) and aeration time (120
min). iHP decontamination caused some damage to copper, brass, chromium plate and galvanized iron immediately after exposure. Repeated iHP decontamination caused marked damage in stainless steel and urethane-, silicone- or epoxy-coating materials. Condensation of iHP decontamination posed
severe damage for the material surfaces. With regard to VHP, 36 kinds of materials were exposed for up to 200 cycles to VHP decontamination. Under dry (dehumidified) conditions, VHP decontamination caused few changes on the surfaces of resin materials in dry conditions, although some resins
began to develop hardening or softening. Discoloration was found in the stainless steel and changes in its coating materials. Bleaching was also observed in wooden materials. Under condensation conditions of VHP, nylon softened and butyl rubber hardened. Condensation of VHP caused material
damage such as discoloration in the stainless steel, corrosion of zinc-plated steel, and air-bubbling under the color-steel sheet. The high concentrations of HP with condensation caused severe changes in metals and resins after repeated exposure. The VHP decontamination tests provided evidence
that the material damage was more severe under condensation conditions than under dry conditions. Our results demonstrate the importance of condensation of HP when using it to decontaminate equipment.
LITERASI DIGITAL DALAM PENGGUNAAN SISTEM INFORMASI PENGENDALIAN TAGIHAN
Authors: Ladyta Intan , Handayani Yosi , Puspita Roza
Published: September 2020

Badan Pengawasan Keuangan Kepuluan Riau  Representative is one of the government institutions which get considerable attention in its financial management. All the money used should be made accountable. Responsibility of each work unit is made using SINTAG application where the result of this input will be compiled into a document of accountability. It would be an update for the treasurer to prepare financial statements. There is  a problem especially in the public relation section and administration chief representative in the input process, there is an error in inputting data  such as and error in typing or nominal numbers. Such errors would generate not accurate and relevant information for expenditure treasurer in which the inputting results will be material information in financial reporting. Based on the results of the study during an apprenticeship at the Supreme Audit Board of Kepuluan Riau Representative Office, it was found that, digital literacy in using system is one of the main concern, the financial sub-section controls this issue by cross-checking the invoice with the result of input to the SINTAG application in the form of a bill control and pay order.
IMPLEMENTASI MOTION GRAFIS VIDEO ANIMASI 2D UNTUK PENGENALAN NIRMANA
Authors: Reno Terrence , Siahaan Arta Uly , Alfian Alfian
Published: September 2020

One of the purpose information technology nowadays is to deliver the information in an interesting way. For example, the using of animation tend to be more interesting to present the information. This project created a 2D animation for introducing Nirmana. Some steps were conducted to finish this product starting with creating the storyboard namely finding the idea and arranging the synopsis, continuing with creating the character sketch and storyboard. After completing this step, the next step is making animation by using Adobe After Effect Software. It is started with editing and composing based on the scene by using Adobe Premiere Pro. Project software. For the final step, the researcher intends to test the using this 2D animation by applying motion graphics as the media for teaching Nirmana to the children. This 2D animation is presented with a colorful layout and completed by voice effect for getting the children’s attention.
LITERASI INFORMASI MAHASISWA TINGKAT AKHIR DALAM MENULIS SKRIPSI DI FISIP UPN “VETERAN” JAKARTA
Authors: Sevilla Vinta , Azwar Azwar
Published: September 2020

This study aims to determine the information literacy of students through the use of e-journal in writing a thesis to complete the final assignment.  The method used is a descriptive quantitative approach through a questionnaire conducted to 155 respondents.  The sampling method uses purposive sampling. This study takes the concept of Big6 information literacy developed by Berkowitz and Eisenberg.  The questions asked to use the variables of the Big6 results. The results of this study are that student information literacy in the use of e-journal to complete the thesis is classified as 'quite good' as the respondents are already used to using electronic and online based media, but in information retrieval is still low with effectively and efficiently.  This is seen from each sub-variable that is submitted through the question items that are answered.
HUBUNGAN MEDIA SOSIAL DENGAN KETERAMPILAN MENULIS PARAGRAF ARGUMENTASI MAHASISWA DI POLITEKNIK NEGERI BATAM
Authors: Lubis Eka Mutia
Published: September 2020

This study aims to determine the relationship between social media and the argumentative paragraph writing skill of Politeknik Negeri Batam students. This study employs a descriptive method, with 70 students as the research subjects. In this study, students were asked to do a practice in the form of writing an argumentative paragraph. An analysis from the obtained data is then conducted to find out their mastery in composing a paragraph. As the basis for the assessment, scores in unity, coherence, and development aspect were assigned to each paragraph. These three aspects were then collected and summed up to find the mean of the data, which had been grouped and assigned score before, to determine their mastery level in writing an argumentative paragraph. Subsequently, the data were inserted into a table. Based on the table, which recapitulates the mastery level in writing an argumentative paragraph, the results are as follows: 43 % of the students have a high level of mastery, with 58 % of them having access to social media; 37 % of the students are in the medium level of mastery, with 28 % of them having access to social media; 20 % is in the low level of mastery, with 13 % of them having access to social media. The results of this study show that students who are active in social media have the ability to write a good argumentative paragraph. This might be due to the fact that activities in social media enhance their writing skill, which is closely related to the four aspects of language competencies, which consist of observing, reading, listening, and writing.
Streaming Android Terintegrasi dengan Sensor PIR sebagai Sensor Gerak
Authors: Khoirunnisa Adila
Published: September 2020

Streaming merupakan proses pengiriman data secara berkelanjutan yang memungkinkan pengguna mengakses file yang belum diterima secara keseluruhan. Metode streaming dapat diaplikasikan di kehidupan sehari-sehari untuk memantau aktivitas yang sedang berlangsung salah satu contohnya adalah aktivitas di luar pintu. Aktivitas ini dapat bersifat negatif maupun positif. Berdasarkan permasalahan tersebut, penulis merancang sistem pendeteksian aktivitas dengan menggunakan Passive Infrared Sensor (PIR) yang akan mendeteksi pergerakan dari tubuh manusia. Dengan begitu, sensor PIR dapat menjadi bel rumah otomatis apabila ada orang yang berkunjung. Setelah sensor PIR mendeteksi, maka kamera Android (client) akan aktif dan mengirim pergerakan yang sedang berlangsung ke Android (user) agar pemilik rumah dapat memantau secara langsung. Hasil dari penelitian ini menyimpukan layanan video streaming dengan menggunakan protokol TCP telah memenuhi standar dari Quality of Services (QoS) TIPHON dengan menggunakan parameter delay 3,95745 ms dengan kategori sangat memuaskan, parameter throughput 327637,144 bit per second (bps) dengan kategori sangat memuaskan, serta parameter packet loss 0,952% dengan kategori memuaskan. Berdasarkan penelitian yang telah dilakukan, penulis berharap alat ini dapat membantu pemilik rumah dalam memantau aktivitas yang ada di luar pintu dari mana saja.
Lampu Cerdas Multimode Menggunakan Arduino dengan Kontrol Fuzzy Berbasis Android
Authors: Riski Rullah Siti Febriyanti , Prebianto Nanta Fakih
Published: September 2020

Umumnya pengaturan sebuah intensitas cahaya pada lampu di dalam suatu ruangan dilakukan hanya berdasarkan pada kondisi gelap dan terang yang dilakukan secara manual dan tanpa mempertimbangkan kontribusi cahaya dari luar. Oleh karena itu, diperlukan sebuah alat yang bekerja secara otomatis pada pengontrolan intensitas cahaya lampu untuk meningkatkan efisiensi pemakaian energi listrik. Prinsip kendali yang digunakan pada penelitian ini adalah kendali logika fuzzy dengan sistem inferensi metode Mamdani. Keluarannya diperoleh berdasarkan titik berat dari kurva hasil proses pengambilan keputusan sebagai hasil nilai dari output logika fuzzy. Modul WiFi NodeMCU digunakan sebagai media penghubung kendali yang dikoneksikan ke Android melalui aplikasi Blynk. Dengan pengujian menggunakan metode fuzzy singleton, diperoleh membership function dan membership keluarannya. Agar sesuai dengan intensitas ruangan, maka Set point yg diberikan ialah 40 pada mode tidur, 180 pada mode makan, dan 250 pada mode kerja. Pada mode tidur, diperoleh waktu delay 1,5 detik dan nilai Pulse Width Modulation (PWM) 18 pada kondisi stabil. Pada mode makan, diperoleh waktu delay 3 detik dan nilai PWM 83 pada kondisi stabil. Pada mode kerja, diperoleh waktu delay 3,6 detik dan nilai PWM 116 pada kondisi stabil.
Feelings experienced in hyperbaric oxygen therapy: the users’ voice
Authors: Machado Maria Samya Carvalho , Carvalho Evanilda Souza de Santana , Paranhos Rayssa Fagundes Batista , Costa Cintia Silva de Souza
Published: September 2020

Objetive: To characterize the feelings experienced by users of hyperbaric oxygen therapy (HBOT). Methods: Qualitative study, usingmultiparametric techniques for data collection such as the free word association technique, drawing-and-story procedure with theme and the semistructured interview. For the analysis, the discursive material, together with the visualization of the drawings and the responses of the word-free associations, was cross-referenced and the method of content analysis was employed, thus allowing the feelings experienced at HBOT to be portrayed. Results: The categories emerged: fear and anxiety; feeling of imprisonment and tiredness; happiness and confidence/hope, the latter being subdivided into trust in the therapy and in God. Conclusion: After, the first sessions and especially after the guidance and incentives from the professionals, the negative feelings were softened and gave way to satisfaction, followed by happiness in being able to return to family and social life and all this anchored in the feeling of hope and faith.
Safety of Hydroxychloroquine, Favipiravir, and the Combination of Lopinavir and Ritonavir in the Treatment of the “First Wave” of the New Coronavirus Infection COVID-19
Authors: Romanov B. K.
Published: September 2020

The review compares individual case safety reports (ICSRs) for hydroxychloroquine, favipiravir, and the lopinavir/ ritonavir combination registered in the VigiBase global database during 6 months in 2019 and the same period in 2020 which coincides with the global “first wave”. The aim of the study was to identify specific aspects of using these drugs for the treatment of COVID-19. There was an increase in the use of hydroxychloroquine, favipiravir, and the lopinavir/ritonavir combination during the pandemic, which was accompanied by a significant deterioration in the quantitative and qualitative safety profiles of these drugs. The review summarises the main risks of using these drugs for COVID-19 treatment and highlights the need for revision of the recommendations for their use in the context of the new coronavirus disease.
Marketing Authorisation Based on Incomplete Clinical Data: International Experience and Prospects
Authors: Goryachev D. V. , Uvarova N. E. , Shukshina G. V.
Published: September 2020

No new drug can be used in clinical practice without marketing authorisation. Acquisition of the necessary amount of clinical data may take several years, which is especially critical for pernicious diseases for which no alternative therapy is available. Lack of treatment options creates conditions in which early introduction of efficacious therapy into clinical practice is becoming crucial. This need resulted in the development of new regulatory approaches aimed at accelerated approval of drugs both by reducing the time frame and by fulfilling post-authorisation requirements. The aim of the study was to review regulatory approaches to the accelerated authorisation procedure based on incomplete clinical data, and analyse their potential use in the Russian Federation. The paper presents an overview of authorisation pathways based on incomplete clinical data, which are used by different regulatory authorities, as well as regulatory approaches used in the Eurasian Economic Union (EAEU) and as part of the Russian national authorisation procedure. It was demonstrated that the approaches used by the US, European, and Japanese regulatory authorities, despite some differences, share a common objective of accelerated approval of drugs that fill an unmet medical need. The EAEU also has a conditional approval procedure, but the proposed criteria do not make it possible to use this approach in a real clinical situation of an unmet medical need. A similar national procedure would make it possible to reach a compromise between the needs of the healthcare system and the sound basis for informed decisions of the regulatory authority. Accelerated introduction of novel drugs that address unmet medical needs would set the national regulation in the area of drug circulation on the right track.
Comparison of the World Pharmacopoeias’ Requirements for the Quality of Cell Lines
Authors: Vodyakova M. A. , Sayfutdinova A. R. , Melnikova E. V. , Olefir Yu. V.
Published: September 2020

The cell line is one of the necessary components of a biomedical cell product (BMCP) which can include only viable human cells. In addition, human, animal, insect, or bacterial cell lines can be used as a substrate for the production of some biological drugs. The list of quality parameters and test methods for medicinal products quality control are specified in the State Pharmacopoeia of the Russian Federation, but it contains only a few general monographs on blood products and a few requirements for cell lines as substrates for the production of biological drugs (which cover all types of cells). Currently, there is no regulatory document comparable to the State Pharmacopoeia of the Russian Federation that would contain requirements and test methods for BMCP quality control in the Russian Federation. Thus, one of the issues that arises both during quality control and approval of BMCPs is the lack of a regulatory document defining requirements for BMCP quality parameters and test methods. However, some general monographs of the Russian Pharmacopoeia and other pharmacopoeias can be used for quality control of both cell lines and non-cellular components. The aim of the study was to analyse and compare different pharmacopoeial requirements for the quality of cell lines used as components in human cell- and tissue-based products (comparable to BMCPs), which could be used in BMCP quality control. The paper analyses general monographs of the United States Pharmacopoeia (USP), European Pharmacopoeia (Ph. Eur.), Japanese Pharmacopoeia, Pharmacopoeia of the Republic of Belarus, including general monographs on biological/biotechnological products, because their requirements apply to human cell lines included as components in products similar to BMCPs. The analysed approaches and methods of quality control of cell- and tissue-based products described in the USP and Ph. Eur. could form the basis for elaboration of general monographs for the Russian Pharmacopoeia, including identification, potency, viral safety, and mycoplasma tests that are based on the nucleic acid amplification technology and other tests for cell lines as components of BMCPs.
Stability of the Industrial Reference Standard of Tuberculosis Vaccine (BCG)
Authors: Aleksandrova N. V. , Savina A. A. , Nakonechnaya A. V. , Levi D. T.
Published: September 2020

The industrial reference standard of tuberculosis (BCG) vaccine (IRS), certified and registered by the Federal State Budgetary Institution “Scientific Centre for Expert Evaluation of Medicinal Products” of the Ministry of Health of the Russian Federation (OSO 42-28-420), is used as a reference product in quality control of tuberculosis vaccines BCG and BCG-M. The IRS is a useful means of quality control of these products, as the stability of its proper ties helps to minimise errors during quality evaluation. The shelf life of the BCG vaccine IRS is not more than 2 years if stored at 2–8 °C. It is likely that a vaccine batch could be used as the IRS for a longer period of time. The literature data suggest that the shelf life of a BCG vaccine can be prolonged if it is stored at low temperatures. However, due to significant phenotypic and genotypic differences between BCG sub-strains, the extrapolation of these data to the vaccine produced from the Russian Mycobacterium bovis BCG-I sub-strain requires appropriate testing. The aim of the study was to analyse the possibility of increasing the shelf life of the tuberculosis vaccine IRS by changing the storage temperature. Materials and methods: the effect of low temperatures on the stability of OSO 42-28-420 was studied in commercial batches of tuberculosis vaccine which met all the quality requirements for candidate IRSs. Samples from 6 IRS batches produced from 2014 through 2019 were stored at –(20 ± 1) °С. The stability of their quality characteristics, namely “Specific activity (viability)”, “Total bacterial count”, and “Dispersibility”, was monitored according to the recommendations of the World Health Organization. The obtained data were evaluated relative to the baseline data obtained during certification of each batch. Results: it was demonstrated that there was more than 95 percent probability that the tested parameters would not differ from the initial data if OSO 42-28-420 samples were stored at a low temperature for 5 years. Conclusions: the results obtained support the prolongation of the OSO 42-28-420 shelf life up to 4 years under the recommended storage conditions at –(20 ± 1) °С.
Drug-Induced Neutropenia and Agranulocytosis
Authors: Ostroumova O. D. , Kochetkov A. I. , Pavleeva E. E. , Kravchenko E. V.
Published: September 2020

Drug-induced neutropenia and agranulocytosis are serious and potentially life-threatening complications of pharmacotherapy. The aim of the review was to systematise and analyse scientific literature on the prevalence, risk factors, pathogenesis, clinical picture, methods of prevention and treatment of drug-induced neutropenia and agranulocytosis, and medicinal products that most often lead to their development. The analysis revealed that one of the major reasons of drug-induced neutropenia and agranulocytosis is the use of cytotoxic drugs (alkylating agents, antimetabolites, taxanes), non-steroidal anti-inflammatory drugs, antibiotics, antiplatelet, antithyroid, antirheumatic, antiarrhythmic, and antipsychotic drugs. The incidence of drug-induced neutropenia and agranulocytosis is generally low—from 3 to 16 cases per 1 million patients annually. The main risk factors for the development of these conditions include old age, female sex, history of chemotherapy or radiation therapy, malnutrition, and comorbidities. The symptoms in patients with neutropenia and agranulocytosis regardless of etiology can include fever, chills, apathy, myalgia, weakness, pharyngitis, gingivitis, sinusitis, stomatitis, bronchitis, and sepsis. There are no practical methods for early diagnosis or prevention of drug-induced neutropenia and agranulocytosis. Successful management of these conditions relies on timely identification and immediate withdrawal of the potential causative drug. Prevention of chemotherapy-associated neutropenia may consist in reducing the dose of the chemotherapeutic agent. Practicing physicians should be aware of the risk of drug-induced neutropenia and agranulocytosis. It is important to raise awareness among healthcare professionals of the methods of diagnosis and prevention of these conditions, as well as specific aspects of managing patients with these conditions.
PENGARUH KUALITAS PRODUK DAN PENETAPAN HARGA PAKAIAN BATIK TERHADAP MINAT BELI PELANGGAN PASAR TANAH ABANG
Authors: Dara Nursimah , Purnaningsih Nining
Published: September 2020

The purpose of this research is to examine the effect of product quality and price on consumer buying interest in batik clothes Toko Muda Tanah Abang. The population in this research is all costumers of batik clothing of Toko Usaha Muda Tanah Abang, but the sample used with purposive sampling with customer criteria that have bought batik from Toko Usaha Muda Tanah Abang with the respondents as many as 20 customers. Technique of collecting data that is by method of questioner, interview and documentation. The variables studied include product quality and price as independent variable and buying interest as dependent variable. Data analysis using multiple linear regression. The result of analysis indicate that variable of product quality and pricing have positive and significant influence to the buying interest of Tanah Abang market. Keywords: Product Quality, Price, Interest Buy Consumer Clothing Batik
PENGARUH ALTMAN Z-SCORE” DAN SPRINGATE S-SCORE SEBAGAI ALAT PREDIKSI POTENSI KEBANGKRUTAN TERHADAP HARGA SAHAM (pada perusahaan batubara yang listing di bursa efek indonesia periode 2016-2018)
Authors: Abbas Dirvi Surya , Kusdianto Kusdianto , Inayah Lailatul
Published: September 2020

Penelitian ini bertujuan untuk mengetahui apakah informasi Altman Z-Score” dan Springate S-Score digunakan oleh investor untuk mengambil keputusan investasi yang tercermin dari Harga Saham. Altman Z-Score” dan Springate S-Score yang diukur dengan rasio keuangan yang mencakup yaitu working capital to total asset, retained earning to total asset, earning before interest and taxes to total asset, book value of equity to book value of total debt, net profit before taxes to current liabilities, dan sales to total assets.            Penelitian ini menggunakan sampel perusahaan sektor Batubara selama tahun 2015-2018 dengan menggunakan metode purposive sampling. Data yang digunakan diperoleh dari laporan tahunan yang terdaftar di Bursa Efek Indonesia. Ada 12 perusahaan selama 3 tahun yang memenuhi kriteria. Metode analisis yang digunakan adalah analisis regresi linier berganda dengan bantuan SPSS versi 16.0. Hasil penelitian ini menunjukan bahwa secara parsial Altman Z-Score” dengan Nilai t-hitung Altman Z-Score” sebesar 4,536, sementara ttabel dengan tingkat α = 5%, df (n-k) = 36-2 didapat nilai ttabel sebesar 1.690. Dengan demikian t-hitung Altman Z-Score” (4,536) > ttabel (1.690) dan nilai Sig. 0,000 < 0,05 maka dapat disimpulkan bahwa variabel Altman Z-Score” dalam penelitian ini memiliki pengaruh terhadap Harga Saham. Altman Z-Score” mempunyai koefisien regresi kearah positif sebesar 20,871 (20,87%) dengan Konstanta kearah negatif sebesar -6.900, sementara Nilai t- hitung Springate S-Score sebesar -1.954 sementara ttabel dengan tingkat α = 5%, df (n-k) = 36-2 didapat nilai ttabel sebesar 1.690. Dengan demikian t-hitung Springate S-Score (-1.954) > ttabel (1.690) dan nilai Prob. 0.059 > 0,05 maka dapat disimpulkan bahwa variabel Springate S-Score dalam penelitian ini tidak memiliki pengaruh terhadap Harga Saham. Springate S-Score mempunyai koefisien regresi kearah negatif sebesar -6,220 (62,20%) dengan Konstanta kearah negatif sebesar -6.900.
ANALISIS ETIKA BISNIS DAN KUALITAS PELAYANAN TERHADAP KEPUASAN PELANGGAN DI PT. MODERN MULTI KEMASINDO - TANGERANG
Authors: Ardiansyah Tri Endi , Setiawan Iwan Rofiq , Rahmantika Elin
Published: September 2020

Banyak Kasus bisnis yang terjadi, dimana di masa awal usahanya sangat baik namun harus kandas dalam waktu yang relatif singkat hanya karena tingginya kekecewaan pelanggan sebagai dampak dari etika bisnis yang tidak diterapkan dengan baik. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh etika bisnis dan kualitas pelayanan terhadap kepuasan pelanggan di PT. Modern Muti Kemasindo secara simultan maupun parsial. Penelitian ini menggunakan pendekatan kuantitatif. Sampel pada penelitian ini adalah 92 responden dari total populasi120 pelanggan aktif  PT. Modern Multi Kemasindo. Data yang digunakan adalah data primer dengan survey dan kuisioner. Hasil penelitian menunjukkan bahwa secara parsial etika bisnis (X1) berpengaruh positif dan signifikan terhadap kepuasan pelanggan dan kualitas Pelayanan (X2) secara parsial berpengaruh positif dan signifikan terhadap kepuasan Pelanggan. Secara simultan etika bisnis (X1) dan kualitas Pelayanan (X2) berpengaruh positif dan signifikan terhadap kepuasan Pelanggan (Y). Besarnya pengaruh yang diberikan oleh variabel etika bisnis (X1) dan variabel kualitas pelayanan (X2) terhadap kepuasan pelanggan adalah 54,4 % sedangkan sisanya 45,6% adalah dipengaruhi oleh faktor lain yang tidak diteliti dalam penelitian ini.
Maraş Otu İntoksikasyonu İle Kliniğimize Başvuran Çocuk Olguların Değerlendirilmesi
Authors: GÜNEŞ Hatice , SARIŞIK Nafiz
Published: September 2020

Amaç: Maraş otu (MO), tütün türlerinden olan Nicotina Rustica L. yaprakları ile meşe ve asma odunun küllerinden elde edilen, ağızda çiğnenerek kullanılan toz formunda kullanılan dumansız tütün ürünlerindendir. Bölgemizde halk arasında yaygın kullanımından dolayı çocuk vakaların erişimi kolay olmakta ve özellikle küçük yaş gruplarında ciddi intoksikasyon kliniği ile hastalar acilimize başvurmaktadırlar. Çalışmamızın amacı, acil servisimize MO’ ya bağlı zehirlenme ile başvuran olguların değerlendirilmesi ve genel hatları ile bu ürünün hastalar üzerindeki etkilerinin araştırılmasıdır.
Yöntem: Çalışmaya son 1 yıl içerisinde acil servisimize kazara MO yutmuş, yaşları 10 ay ile 3 yaş arasında değişen, 18 olgu dâhil edilmiştir. Hastalara ait demografik, klinik ve laboratuvar değerleri hasta dosyaları taranarak elde edilmiştir. Ek ilaç alımı olan vakalar dışlanmıştır. Veriler istatistik programına yüklenip değerlendirilmiştir.
Bulgular: Çalışmaya alınan hastaların yaşları 20,5 (10-75) ay iken, bunların 10 tanesini erkek bireyler oluşturmaktaydı. Hastaların venöz kan gazı değerlerinde %33,3’ünde metabolik asidoz vardı; bu hastaların pH değerleri (7,26-7,38) iken HCO3 değerleri (16,12-20,90) mmol/L olarak değişmekteydi. Hastaların % 50’sinin laktik asit düzeyleri üst sınırlarda olup 1,9-6,10 mmol/L arasında değişmekteydi.
Sonuç: MO, içerdiği yüksek nikotin oranından ve diğer maddelerden dolayı özellikle küçük yaş grubunda ciddi toksisitelere sebep olan maddelerden biri olması nedeniyle vakalrın hızlıca değerlendirilip takibe alınması gerekmektedir.
COVID -19 Lockdowns & Social Isolation trauma & Emerging Psychological wellbeing disaster
Authors: ahmed Dr. afaq kazi , Quraishy Dr. Saadia , Chandani Seema
Published: September 2020

1. Methodology

2.1 Study population and
sample

The target population selected
for the feedback consisted
of people living in Karachi, the biggest city of Pakistan, an industrial hub,
and a port city comprising over 15 million
population. The demographics included age, gender, profession, students,
working, non-working, retired, etc. The city was under complete lockdown since
the 1st week of April. The study conducted in the third week from
April 16-23, 2020 for assessment of the mental health of the population in the
context of lockdown and confinement due to COVID-19 in Pakistan. Because of the large population, the stigma
attached to mental health, and ethical considerations the questionnaire was
kept anonymous and the non-probability convenience sampling technique was used.

2.2 Rating instruments

The Research instruments
PHQ-9 was used for the assessment of the mental health of the population (Hartung
et al., 2017; Hinz et al., 2006) under three week's lockdown during COVID-19. Patient
Health Questionnaire (PHQ-9) is a nine-item depression severity measuring
instrument with a total score of 20. Depression Severity Scores represent: 0-5
= Mild, 6-10 = Moderate 11-15 = Moderately Severe 16-20 = Severe Depression (Kroenke
et al., 2010).

2.3 Data analysis

PHQ-9 and GAD-7 forms
designed on Google form and survey was conducted online sharing the link via
Emails, Whatsapp, Facebook, and LinkedIn using 120 research volunteers. The
respondent cooperation and readiness were high as it was anonymous, easy to
complete within 3 minutes, and submission over a single click through their cell
phone. The survey started on 16th April and was completed within
seven days by April 21. The 6876 respondents completed the
questionnaire included in the final analysis. The statistical analytical tool
SPSS was implied for descriptive analyses. Initially,
descriptive analysis was conducted to describe the demographic characteristics
of people of Karachi under lockdown for the last three weeks (April 16 to April
23). Secondly, the prevalence of severity of depression symptoms was measured
on a rating scale of minimal, mild, moderate, and severe stratified by gender,
age, and occupation.

2.4 Ethical considerations

The ethical committee of qualified
psychiatrists and psychologists of BasicNeeds Pakistan endorsed the study. The
respondents were not required to provide any personal information and identity
to keep the survey anonymous; consequently, they participated in the study.

2.5 Demographic information

The demographic elements
consisted of age (18-65 in five
categories), gender (Male & Female), professionals, students, and
entrepreneurs (self-employed and owners of the SMEs). The study was confined to
the urban population who faced strict lockdown
restrictions and complete closure.