bluuebunny/crossref_metadata_2025 huggingface dataset:
A pro-inflammatory diet is associated with an increased odds of periodontitis: finding from a case–control study
Authors: Ghaemmaghami Reihaneh Sadat , Bayani Mojtaba , Nakhostin Afrooz , Vahid Farhad
Published: September 2023

Objective

This study aimed to evaluate the inflammatory effect of diet using the dietary Inflammatory Index (DII) on the odds of periodontitis. We hypothesized that a diet with high DII scores (a pro-inflammatory diet) is associated with high chronic and systematic inflammation resulting in periodontitis.

Periodontitis is one of the most common inflammatory diseases that affect the tissues around the tooth and results from the interaction of bacterial infection and the host immune response. The DII shows the association between different food components and the level of specific inflammatory biomarkers.

Method

The food intake of 87 cases with diagnosed periodontitis and 87 control was assessed using a 163-item valid food frequency questionnaire (FFQ). The DII was calculated based on the FFQ data. Logistic and linear regression models adjusting for multivariable confounders were used to investigate the odds ratio (OR) and 95% confidence intervals (CI) of developing periodontitis.

Results

There was a significant difference between the mean intake of micronutrients and food groups, including saturated fatty acids (SFAs), iron, magnesium, manganese, vitamin C, crude fiber, selenium, chromium, whole fiber, caffeine, dairy, and meat, between patients with periodontitis and the control group (p-value˂0.05). DII scores in this study ranged from -3.13 to + 0.99. However, the periodontitis OR in the raw and multivariable-adjusted models was not statistically significant (multivariable-adjusted OR tertiles 1 vs. tertiles 3 = 2.00, 95%CI: 0.4–90.42, p-value = 0.08). A similar result was also observed in the continuous model of DII (multivariable-adjusted OR DII continuous = 1.93, 95%CI: 0.30–98.79, p-value = 0.05).

Conclusion

Although the OR was not statistically significant in crude models, a significant trend was found in multivariable-adjusted models. The results were promising since this is the first study to examine the association between diet-induced inflammation and dental disease. It is advisable to conduct additional studies with high sample sizes and other designs, such as prospective studies.
Estimating the Lifetime Treatment Burden of Patients With Follicular Lymphoma: A Retrospective Study Using Real-World Multicenter Data
Authors: Rajamäki Aino , Hujo Mika , Sund Reijo , Prusila Roosa E.I. , Kuusisto Milla E.L. , Kuitunen Hanne , Jantunen Esa , Mercadal Santiago , Sorigue Marc , Sancho Juan-Manuel , Sunela Kaisa , Kuittinen Outi
Published: September 2023

PURPOSE

Although follicular lymphoma is characterized by long natural history and frequent relapses, data on the number of patients receiving subsequent therapy lines are scarce. To perform reliable health economical calculations for various treatment options, data regarding the lifetime number of therapy courses are needed. The purpose of this study was to use real-world data to create a model that could estimate the treatment burden over a 20-year period.

MATERIALS AND METHODS

We performed a 20-year simulation on the basis of retrospectively obtained multicenter data of 743 patients with follicular lymphoma. The simulation was carried out in two steps: First, a competing risk model on the basis of Weibull distribution was used to simulate the state transitions from diagnosis onward and from first-line therapy onward. Then, the data were completed by imputing on the basis of the existing data. Completion of data was repeated for 1,000 times to estimate reliability.

RESULTS

In 20 years, 97% (2.5-97.5 percentile range: 96%-98%), 66% (61%-70%), 34% (30%-41%), and 15% (9%-18%) of the patients received first-line, second-line, third-line, and fourth-line therapies, respectively. The median number of therapy lines received by each patient was two.

CONCLUSION

Despite long remissions, approximately two thirds of the patients receive at least two lines and one-third at least three lines of therapy during their lifetime.
Approach the Patient With Obstructive Sleep Apnea and Obesity
Authors: Meyer Emily Jane , Wittert Gary Allen
Published: September 2023

Obstructive sleep apnea (OSA) and obesity are highly prevalent and bidirectionally associated. OSA is underrecognized, however, particularly in women. By mechanisms that overlap with those of obesity, OSA increases the risk of developing, or having poor outcomes from, comorbid chronic disorders and impairs quality of life. Using 2 illustrative cases, we discuss the relationships between OSA and obesity with type 2 diabetes, dyslipidemia, cardiovascular disease, cognitive disturbance, mood disorders, lower urinary tract symptoms, sexual function, and reproductive disorders. The differences in OSA between men and women, the phenotypic variability of OSA, and comorbid sleep disorders are highlighted. When the probability of OSA is high due to consistent symptoms, comorbidities, or both, a diagnostic sleep study is advisable. Continuous positive airway pressure or mandibular advancement splints improve symptoms. Benefits for comorbidities are variable depending on nightly duration of use. By contrast, weight loss and optimization of lifestyle behaviors are consistently beneficial.
An Unusually Prolonged Case of FGF23-mediated Hypophosphatemia Secondary to Ferric Carboxymaltose Use
Authors: Arora Ipsa , Kaprove Alison , Perrone Ronald , Ceglia Lisa
Published: September 2023

Ferric carboxymaltose (FCM)-induced hypophosphatemia is seen in up to 75% of patients receiving this therapy for iron deficiency anemia. Hypophosphatemia has been attributed to increased circulating levels of fibroblast growth factor-23 (FGF23), the transcription of which is upregulated in an iron-deficient state. However, hypophosphatemia typically resolves within 12 weeks of FCM administration. Here, we present a case of unusually prolonged hypophosphatemia that developed after treatment with FCM in a 39-year-old female with autosomal dominant polycystic kidney disease (ADPKD) but normal renal function. Workup was significant for low tubular reabsorption of phosphate and inappropriately normal FGF23. Genetic disorders of hypophosphatemia and a FGF23-secreting tumor were ruled out. Treatment with calcitriol was required for nearly 3.5 years. The prolonged hypophosphatemia was attributed to underlying ADPKD because these patients demonstrate inappropriately elevated FGF23 levels for the degree of severity of reduced glomerular filtration rate. However, the stimulus driving FGF23 secretion in these patients is incompletely understood. Elevated FGF23 in the kidney suppresses renal tubular phosphate reabsorption and 1α-hydroxylase activity ultimately leading to hypophosphatemia. We conclude that our patient was at a high risk of developing hypophosphatemia because of underlying ADPKD, and FCM was the likely precipitant to identify this underlying process.
Emigration with a Pulled Handbrake: Friedrich A. Lutz's Internal Methodenstreit
Authors: Grudev Lachezar
Published: September 2023

This article reconstructs the path of the German economist Friedrich A. Lutz (1901–75) to American economics. The correspondence with his former teacher Walter Eucken, the founder of the Freiburg school, constitutes a crucial yet unexplored source for the article. Through Lutz's case, this article demonstrates the growing gulf between German and Anglo-Saxon economics during the late 1930s. In his native Germany, Lutz was trained in methodologically and institutionally focused economics, which differed fundamentally from the mathematical economics dominating Anglo-Saxon academia. He realized that an academic career in the United States would be impossible if he did not adapt to the new methods and if he did not abandon the methods of the German tradition. This gave rise to his internal Methodenstreit. After his emigration in 1938, he constantly experienced doubts and tensions because he was convinced that without considering institutions, mathematical economics could never explain the occurrence and essence of macroeconomic phenomena. Despite his stellar career at Princeton, it was only after his move to Zurich in 1953, where he taught history and theory of socioeconomics for the rest of his life, that Lutz could reconcile this internal Methodenstreit.
“What Fits in One Hand”
Authors: Rosón María , Pol Ana
Published: September 2023

This article examines the relationships that developed in exile between women writers and artists and things following the Spanish Civil War. Our analysis is based on self-writing and visual art. Using a New Materialist theoretical framework, the article shows how, for these women in exile, things had agency, producing entanglements, ruptures (desgarros), or moorings necessary for a new orientation. Disorientation, arising from the new social and geographical context of exile, also affects the uses and function of things. This produces a subjectivity saturated by material phenomena, the relationship with which is heightened by the experience of fleeing one’s country. The writers and artists discussed include Victorina Durán, Mada Carreño, María Luisa Elío, Silvia Mistral, María Teresa de León, Concha Méndez, and Maruja Mallo. All of them went into exile in Spanish-speaking countries in Latin America, specifically Mexico, Argentina, and Chile.
Objective Vision
Authors: Dobson James E.
Published: September 2023

Convolutional neural networks (CNNs) are a key technology powering the automated technologies of seeing known as computer vision. CNNs have been especially successful in systems that perform object recognition from visual data. This article examines the persistence of a mid-twentieth-century ontology of the digital image in these contemporary technologies. While CNNs are multidimensional, their ontology flattens distinctions between background and foreground, between subjects and objects, and even the relations established among the categories of information used to organize and train these models. This ontology enables the introduction and amplification of bias and troubling correlations and the transfer or slippage of learned associations between humans and objects found in the training image archives. Inspecting and interpreting what CNNs learn and index through their complex architectures can be difficult if not impossible because of how they encode and obfuscate quite human ways of seeing the world and the image repertoires used to train these algorithms that are rife with residues of prior representations.
Playing and Hiding Joyfully in the Rubble
Authors: Desloover Elyx , Bey Marquis
Published: September 2023

Marquis Bey's Black Trans Feminism (2022) puts forth radical gender abolition as the necessary actualization of blackness and transness toward hopeful world de/construction. An intentional, ongoing work of stepping aside from expected regimes replaces material identitary stances and aims to embrace possibility rather than hold us down. The present conversational piece, fostering critical reflection in/on kinship and interested in evading disciplinary pledges, explores underlying themes of Bey's fugitive theorization, such as undefining, opacity, queer excess, playful performativity, and the destabilization of “solid” ground. Desloover and Bey discuss the avoidance of ontological gendering violence in practice and the necessary forgoing of identities held near and dear. They touch on xenogender proliferation, which could lead not only to fracturing the oppressive binary but also to obliterating gender as colonial cis-heteropatriarchy knows it — to release the need for “making sense” and let it remake itself over and again. Bey describes the stifling experience of (en)forced embodiment of attributed/assumed privilege, claiming nonbinariness on/as the way to wider spaces that skirt required legibility. How can we run (off) from socially imposed and oppressive terrain that forecloses possible unruly existences? Yearnings for the vastness of the “not quite” that-which-is-given ripple beneath the surface of the nameable and speak ofthe elsewhere Bey desires without tying it too tightly to defining words. Playful joy from and for radically healing openness is shared and upheld here to elude the paralyzing exhaustion caused by a “cistem” that cannot possibly hold us.
When My Brown Got Colored
Authors: Sathi Sreerekha
Published: September 2023

This essay is a testimonial of the author’s experiences, memories, and reflections about becoming a person/woman of color, discovering, and unearthing the meanings of racialization, white privilege, and white supremacy in the contemporary United States. The author gives voice to her new migrant experience as a Brown woman from India, positioning her reflections and learnings amidst the history and politics of colonialism and capitalist development, linking it to contemporary neoliberal academia in the United States. By sharing some events and encounters in her relatively short stint in Charlottesville, Virginia, between 2016 and 2019, the author reviews her attempts to critically analyze concepts like women of color, diversity, colorism, privilege, invisibility, and othering. The article further connects some of the author’s experiences of racialization in view of the growing politics of casteism and Brahmanical supremacy in India, locating and reassessing herself in the midst of Trump’s hardened propagation of white privilege in the United States and Modi’s Hindutva, both emanating a politics rooted in racialization, exploitation, and marginalization of the other.
A Conversation with Doris H. Gray on the Power and Limitations of Restorative Justice across History, Culture, and Gender
Authors: Cohen Rosetta Marantz , Gray Doris H.
Published: September 2023

This interview with Doris H. Gray, author of Leaving the Shadow of Pain: A Cross-cultural Exploration of Truth, Trauma, Reconciliation, and Healing, explores the impact of political trauma across time, and the strategies for healing and justice. The conversation with Gray focuses on the ways in which her own experiences, as the child of a traumatized German Jew, intersect with those of formerly persecuted and incarcerated Tunisian women before and after the Arab Spring. What are the possibilities and limitations of restorative justice for those haunted by history?
Meningeal origins and dynamics of perivascular fibroblast development on the mouse cerebral vasculature
Authors: Jones Hannah E. , Coelho-Santos Vanessa , Bonney Stephanie K. , Abrams Kelsey A. , Shih Andy Y. , Siegenthaler Julie A.
Published: September 2023

Perivascular fibroblasts (PVFs) are a fibroblast-like cell type that reside on large-diameter blood vessels in the adult meninges and central nervous system (CNS). PVFs contribute to fibrosis following injury but their homeostatic functions are not defined. PVFs were previously shown to be absent from most brain regions at birth and are only detected postnatally within the cerebral cortex. However, the origin, timing and cellular mechanisms of PVF development are not known. We used Col1a1-GFP and Col1a2-CreERT2 transgenic mice to track PVF development postnatally. Using lineage tracing and in vivo imaging we show that brain PVFs originate from the meninges and are first seen on parenchymal cerebrovasculature at postnatal day (P) 5. After P5, PVF coverage of the cerebrovasculature expands via local cell proliferation and migration from the meninges. Finally, we show that PVFs and perivascular macrophages develop concurrently. These findings provide the first complete timeline for PVF development in the brain, enabling future work into how PVF development is coordinated with cell types and structures in and around the perivascular spaces to support normal CNS vascular function.
Light-activated BioID – an optically activated proximity labeling system to study protein–protein interactions
Authors: Shafraz Omer , Davis Carolyn Marie Orduno , Sivasankar Sanjeevi
Published: September 2023

Proximity labeling with genetically encoded enzymes is widely used to study protein–protein interactions in cells. However, the accuracy of proximity labeling is limited by a lack of control over the enzymatic labeling process. Here, we present a light-activated proximity labeling technology for mapping protein–protein interactions at the cell membrane with high accuracy and precision. Our technology, called light-activated BioID (LAB), fuses the two halves of the split-TurboID proximity labeling enzyme to the photodimeric proteins CRY2 and CIB1. We demonstrate, in multiple cell lines, that upon illumination with blue light, CRY2 and CIB1 dimerize, reconstitute split-TurboID and initiate biotinylation. Turning off the light leads to the dissociation of CRY2 and CIB1 and halts biotinylation. We benchmark LAB against the widely used TurboID proximity labeling method by measuring the proteome of E-cadherin, an essential cell–cell adhesion protein. We show that LAB can map E-cadherin-binding partners with higher accuracy and significantly fewer false positives than TurboID.
Regulation Design in Insurance Markets
Authors: Bhaskar Dhruva , McClellan Andrew , Sadler Evan
Published: September 2023

Regulators often impose rules that constrain the behavior of market participants. We study the design of regulatory policy in an insurance market as a delegation problem. A regulator restricts the menus of contracts an informed firm is permitted to offer, the firm offers a permitted menu to each consumer, and consumers choose contracts from offered menus. If consumer types and firm signals are ordered in a way that reflects coverage need, the regulator can leverage the firm’s information by forcing the firm to offer specified additional options on each menu. Several extensions illustrate the practical application of our results. (JEL D21, D43, D82, D86, G22, G28, L51)
A cross-sectional study to assess the morbidity pattern among female agricultural workers in the rural area of Central India: a study protocol
Authors: Yadav Deepika , Mehendale Ashok , Muneshwar Komal
Published: September 2023

Agriculture serves as the primary source of income for a substantial number of agricultural workers, with a significant portion of the Indian population, especially in rural areas, engaged in this occupation. However, the health status of female agricultural workers is often adversely affected by various factors, including working conditions, environmental exposure, and other morbidities. As a result, they are at risk of developing several diseases, such as tuberculosis, diabetes, hypertension, lung disease, muscle pain, joint pain, and pesticide poisoning, which constitute the main occupational health concerns in this sector. Unfortunately, despite the prevalence of these health risks, many female agricultural workers do not prioritize their own health and wellbeing. According to the latest survey data by the National sample survey office (NSSO), around 54% of the Indian workforce is engaged in agriculture, mainly in rural areas.

There are no unions for female agricultural workers, and they cannot receive occupational health facilities and social security schemes provided to them. This study aims to understand female agricultural workers and health-seeking behaviours and morbidities. Objectives- This study assesses the morbidity pattern among female agricultural workers and the health-seeking behaviour of female agricultural workers. It also identifies the utilization of social security schemes among female agricultural workers in villages.

The study focuses on assessing the morbidities among female agricultural workers aged 18 and above residing in the villages of Wardha district of Maharashtra. For this purpose, A pretested questionnaire covering sociodemographic data, morbidity profile, socioeconomic variables, family, education, and social security measures will be utilized. The study aims to conduct a community-based cross-sectional survey among 131 female agricultural workers from the specified region.
Inventory: Yesterday and Today
Authors: Mislavskaya N.
Published: September 2023

The article provides a retrospective analysis of the role and importance of inventory, both in the process of economic activity and in the accounting system. The transformation of the inventory from the main accounting method to one of the parity methods of accounting and preparation of accounting (financial) statements is traced. The innovations introduced by the relevant Federal Accounting Standards, which will come into force in 2025, are also analyzed. The conclusion is made about the increasing role of inventory at the present stage of development of accounting knowledge.
Rozporządzenie eIDAS jako samoistna podstawa wnoszenia pism procesowych drogą elektroniczną?
Authors: Kaczmarek-Templin Berenika
Published: September 2023

Przedmiotem rozważań zawartych w artykule jest analiza zagadnienia bezpośredniego stosowania przepisów rozporządzenia eIDAS w krajowym postępowaniu cywilnym. Zasadniczo akt ten dotyczy prawa materialnego, tj. reguluje rodzaje podpisów elektronicznych i inne sposoby elektronicznej identyfikacji. Wprowadza także zasadę, w myśl której zrównane zostały skutki prawne podpisu własnoręcznego i podpisu elektronicznego. Daje to asumpt do rozpatrywania możliwości wniesienia drogą elektroniczną pisma procesowego, które zostanie opatrzone podpisem elektronicznym. Jak wynika z regulacji Kodeksu postępowania cywilnego, ustawodawca podejmuje próby umożliwienia stronom wnoszenia pism w sposób elektroniczny. Aktualnie jedynie elektroniczne postępowanie upominawcze daje realną możliwość korespondencji z sądem z pominięciem tradycyjnej drogi papierowej. Niemniej jednak wdrożenie funkcjonowania systemu teleinformatycznego pozwoli zrealizować taką możliwość także dla innych rodzajów postępowań. Dopóki jednak możliwość wnoszenia pism drogą elektroniczną nie będzie wynikała z przepisów i jednocześnie z możliwości technicznych sądów, rozporządzenie eIDAS nie może być traktowane jako samodzielna podstawa do skutecznego składania pism elektronicznie.
Tendencje rozwojowe polityki egzekwowania prawa antymonopolowego Unii Europejskiej na rynkach cyfrowych – od decyzji Komisji Europejskiej w sprawach Google do regulacji sektorowej
Authors: Kolasiński Marek
Published: September 2023

W artykule przedstawiono tendencje rozwojowe polityki egzekwowania prawa antymonopolowego Unii Europejskiej na rynkach cyfrowych. Autor rozpoczyna swoje wywody od zarysowania serii decyzji Komisji Europejskiej dotyczących praktyk rynkowych Google i analizy założeń teoretyczno- prawnych, na których opiera się wyrok Sądu Unii Europejskiej w sprawie Google Shopping, a następnie podejmuje próbę przedstawienia skutków rynkowych przedmiotowych działań unijnego organu ochrony konkurencji. Autor sceptycznie odnosi się do gospodarczej efektywności wskazanych decyzji Komisji Europejskiej oraz zwraca uwagę na zagrożenia wiążące się ze zwiększaniem antymonopolowego interwencjonizmu. W publikacji wskazano w szczególności na ryzyko nadmiernego rozluźnienia dyscypliny analitycznej w sprawach antymonopolowych. W artykule wyrażono natomiast aprobatę wobec działań legislacyjnych idącychw kierunku objęcia rynków cyfrowych regulacją sektorową. Autor uważa, że takie rozwiązanie umożliwi osiągnięcie powszechnie akceptowanych celów publicznych, a nie kreuje zagrożeń wiążących się z dalszym zaostrzaniem polityki egzekwowania prawa antymonopolowego.
Zrównoważona polityka oświetlenia zewnętrznego w mieście. Studium przypadku Kopenhagi
Authors: Szlachetko Katarzyna
Published: September 2023

Kopenhaga jest wzorcowym przykładem tego, że polityka miejska w zakresie zrównoważonego oświetlenia zewnętrznego może być kształtowana nawet wtedy, gdy w porządku krajowym (ustawowym) brakuje wyraźnych „twardych” podstaw prawnych do jej wdrażania i prowadzenia. W tym zakresie miasto Kopenhaga korzysta z konstytucyjnie przyznanej samodzielności prawnej, realizując zadania z zakresu planowania przestrzennego, ochrony środowiska i procesu inwestycyjno-budowlanego. Sukces Kopenhagi opiera się na umiejętnym programowaniu polityk miejskich. Cele i sposoby ich realizacji są formalizowane w komplementarnych strategiach i aktach wykonawczych, które tworzą spójną wizję rozwoju Kopenhaga jest przykładem wszechstronnego (multidyscyplinarnego) podejścia do zarządzania infrastrukturą oświetlenia zewnętrznego w ramach zrównoważonej polityki dostosowanej do potrzeb ludzi, środowiska i gospodarki, kształtowanej w miejskim planie adaptacji do zmian klimatu, w strategii oświetlenia dla miasta oraz w operacyjnym masterplanie oświetlenia zewnętrznego.
Glosa do wyroku Sądu Najwyższego z dnia 20 kwietnia 2021 r., V CSKP 34/21
Authors: Drewek Marcin
Published: September 2023

Glosowany wyrok zasługuje na przynajmniej kilka słów komentarza Po pierwsze, z uwagi na ważką problematykę normatywną dotyczącą tzw. zasad słusznościowych. Po drugie, z tego względu, że orzeczenie to wpisuje się w aktualnie prowadzoną dyskusję na temat aksjologii stosowania niektórych instrumentów praktyki kontraktowej instytucji finansowych Chodzi mianowicie zwłaszcza o dwie rozważane przez Sąd Najwyższy kwestie: ram prawnych stosowania konstrukcji przewłaszczenia nieruchomości na zabezpieczenie oraz dopuszczalności stosowania art 5 k c do potrącenia ustawowego Do przyjętych w komentowanym wyroku stanowisk należy się odnieść z aprobatą Przemawiają za tym argumenty wskazane w treści niniejszej glosy.
Experiences of Postpartum Depression in Men: A Qualitative Meta-synthesis
Authors: Seo Hye Gyeong , Kim Suk-Sun
Published: September 2023

Purpose: This study aimed to comprehensively review the experiences of postpartum depression in men.Methods: A qualitative meta-synthesis suggested by Noblit and Hare was conducted in this study. Three qualitative studies were chosen and synthesized to describe men's experiences of postpartum depression. Results: Four themes emerged as a result of synthesizing: “Frustration stemming from excessive responsibility as a father”, “Life of mine being tied to child-rearing”, “Suppression of emotions due to gender role stereotypes”, and “Communication interruption with wife due to marital conflict”. Conclusion: The results of this study provided a deeper understanding of the experiences of postpartum depression in men, and can help establish prevention program and arrang social support for postpartum depression in men.
Effects of Physical Activity on Reducing Depression and Menopausal Symptoms: A Meta-Analysis
Authors: Park Seong-Hi , Han Kuem Sun , Jang Youn Jung
Published: September 2023

Purpose: This study systematically reviewed the effects of physical activity on depression and various menopausal symptoms in middle-aged women. We aimed to identify physical activity as a useful intervention for mitigating the physiological and psychological challenges associated with menopause and promoting healthy aging.Methods: Electronic searches were conducted in the MEDLINE, EMBASE, CINAHL, and the Cochrane Library databases using predefined keywords “menopause” and “physical activities”. Of the 1,391 initial articles, 15 randomized controlled trials involving 1,692 middle-aged women were included.Results: Physical activities led to a reduction in depressive symptoms, with a standardized mean difference (SMD) of -0.60 (95% CI, -0.90 to -0.30). Moreover, all menopausal symptoms, except vasomotor symptoms, were decreased. Specifically, the SMDs for the five subscales of menopausal symptoms were as follows: total scores: -1.53 (95% CI, -2.57 to -0.49); vasomotor: -0.76 (95% CI, -1.53 to 0.00); psychological: -0.93 (95% CI, -1.62 to -0.25); physical: -1.10 (95% CI, -1.77 to -0.43); and urogenital/sexual: -0.67 (95% CI, -1.23 to -0.12).Conclusion: Physical activity is beneficial for middle-aged women transitioning from peri- to post-menopause. Engagement in physical activity can contribute to the maintenance of overall health and well-being during aging by reducing depression and menopausal symptoms.
Overcoming lymphorrhoea: a step to achieve a better life with lymphoedema
Authors: Ramadan Francesca
Published: September 2023

Lymphorrhoea—otherwise known as ‘wet’ or ‘leaky’ legs—is an increasingly common condition that many community nurses will encounter in their daily practice; however, until relatively recently, evidence-based literature on its management was limited, and treatment modalities only tackled the symptoms instead of addressing the cause. In this article, Francesca Ramadan highlights the devastating impact of this condition, and the resources available to community practitioners to assist their patients to live well with lymphoedema.
A poesía será monógama e monosexual até que se demostre o contrario
Authors: Lema París Ánxela
Published: September 2023

Este artigo convida á reflexión arredor dos discursos constituíntes do canon e o imaxinario lector, cuxa influencia semella condicionar o proceso de lectura negando sexualidades non-normativas e reforzando un pensamento hexemónico asentado en valores tales como a heterosexualidade, a monogamia e a monosexualidade. Nun xénero como o poético, necesitado dun lectorado activo, a interpretación dos textos desde o punto de vista da sexualidade ofrece datos aos que cómpre atender sobre os mecanismos que operan e condicionan de maneira inconsciente o acto de lectura. Embora Barthes anunciara a morte da autoría, descóbrense pegadas biográficas pendentes de análise co obxectivo de visibilizar a pluralidade e diversidade propias da palabra poética.
¿Una pizca de antropomorfismo no(s) basta(rá)?
Authors: Milone Gabriela
Published: September 2023

Este trabajo discute el problema de la interpretación y las posiciones enunciativas en el marco de la crítica general al antropocentrismo en la escena teórica actual. Las preguntas por quién interpreta y mediante qué lenguaje conducirán la reflexión hacia ciertos usos del antropomorfismo, cuestión que deja en evidencia dos puntos clave: la contradicción perfomática y la pretensión de literalidad como estrategia para evitar posiciones enunciativas antropocentradas. Un poema de la poeta argentina Beatriz Vallejos acompaña la reflexión y da una clave para pensar estas cuestiones. Se postula, finalmente, una categoría para continuar con el análisis: la ficción teórica y su potencia crítica ante el reto imaginativo que exigen los gestos críticos en la actualidad.
Entre la pausa y la urgencia. Reflexiones sobre la escritura crítica en tiempos de desastre, a partir de Lo viral, de Jorge Carrión y Lo que no vemos, lo que el arte ve, de Graciela Speranza
Authors: Peller Diego
Published: September 2023

El objetivo del presente artículo es proponer una reflexión sobre las diferentes modalidades de la escritura crítica en relación con nuestra contemporaneidad pospandémica, marcada por una crisis ecológica global sin precedentes. Nos proponemos caracterizar y contraponer, en el campo de la escritura crítica, dos regímenes de temporalidad específicos, uno que privilegia la respuesta urgente ante la crisis, frente a otro que apuesta por una temporalidad más lenta, y se demora en la atención a la singularidad de las obras analizadas. Esta caracterización se pone a prueba en el comentario de los ensayos críticos recientes Lo viral, de Jorge Carrión (en el que prevalece la primera modalidad) y Lo que no vemos, lo que el arte ve, de Graciela Speranza (en el que, según sostenemos, prevalece la segunda modalidad).
Encrucijadas en el desierto blanco. Viajes de descubrimiento y expediciones científicas en Werner Herzog y Adriana Lestido
Authors: Accossano Pérez Natalia
Published: September 2023

En este trabajo nos proponemos estudiar dos obras ­—una fílmica y otra literaria­— que se originan en viajes al antártico desierto blanco. Los paisajes que se presentan, poéticamente, en estas obras son desolados, amenazadores y están aislados, características los vinculan con la categoría estética de lo sublime. En Encounters at the End of the World (2007), el realizador Werner Herzog convive con los científicos de la estación antártica de McMurdo y los retrata en tanto figuras de ese paisaje blanco. En Antártida negra (2017), la fotógrafa Adriana Lestido emprende un viaje en busca del blanco absoluto. A partir de lo anterior, nos proponemos estudiar de qué modo estas obras participan de los paisajes de lo sublime: qué cambia, qué permanece, qué se buscaba y qué se encontró finalmente; y cómo se representa esa soledad y esa pureza en nuestro tiempo.
Gentrificación lenta
Authors: Durán Gustavo , Mérida Juan
Published: September 2023

Si la investigación sobre la gentrificación en Latinoamérica ha sido reducida, en ciudades andinas como Quito es prácticamente inexistente. Mediante un estudio sobre diferentes formas de transformación socioespacial de cuatro casos divergentes y paradigmáticos de Quito, se muestran las formas en que se expresa la gentrificación durante la primera quincena del siglo XXI, contexto marcado por un mayor intervencionismo del Estado e incremento de la clase media. A partir de la comparación de casos desde un enfoque que relaciona la escala barrial y metropolitana, el estudio concluye que las principales transformaciones socioespaciales en Quito tienen carácter periurbano y están promovidas por el Estado. No obstante,  el predominio de la clase popular en el espacio urbano lleva a procesos de gentrificación lenta y desplazamiento indefinido.
Buddhist Antidotes against Greek Maladies: Ritschl, Harnack, and the Dehellenization of Intercultural Philosophy
Authors: Muller Fabien
Published: September 2023

abstract: One of the most prolific approaches to the comparative study of Buddhist and Christian philosophy has been the use of Buddhist anti-metaphysicism to overcome the allegedly obsolete metaphysical discourse of Christianity. This approach has been practiced, among others, by Edgar Bruns, Frederik Streng, Joseph O'Leary, and John Keenan. Keenan's 1980–1990s seminal works were determinative in that they appeared to rely on intuitive and evident premises: Christianity became infused with Greek metaphysical concepts early on; consequently, it adopted the forms of essentialism and ontological discourse practiced in metaphysics. That discourse has now become obsolete and must be overcome; Buddhist anti-metaphysicism helps overcome it; hence, Christianity can learn from Buddhism. In this paper, I show that although Keenan presents the first of these claims as self-evident, it is in fact highly polemical. Its origins lie in Albrecht Ritschl's and Adolf von Harnack's Hellenization theory. While the theological and historical background to this theory has been debated, Keenan does not engage in these debates. Even more, he transforms the theory in such a way that it becomes incongruent with its inherent aim. Following the problems implied on these two levels, I suggest that Keenan's project makes itself vulnerable to incoherencies. In the end, I argue for the overcoming of antimetaphysicism as a basis for Buddhist-Christian dialogue.
Buddhist-Christian Resources for Spiritual Care: A Scoping Review and Projection
Authors: Bidwell Duane R.
Published: September 2023

abstract: Despite the maturing and formalizing of Buddhist-Christian studies as an academic discipline, its practical and pastoral implications are insufficiently addressed. Most of the practical literature to date addresses spiritual care, broadly conceived, within a narrow range of sources and theories. This scoping study identifies three primary resources offered to providers of spiritual care by scholars of Buddhist-Christian studies: an expanded theoretical base for assessment and interpretation, practices for caregiver formation and cultivation, and guidance for care with spiritually fluid people. Scholars of Buddhist-Christian studies could make at least four additional contributions to chaplaincy and spiritual care: a revised telos of care, attention to care as a site of spiritual practice, criteria for salutogenic spiritualities, and refined practices for interreligious and postcolonializing care. These potential contributions require the discipline to carefully consider methodological issues and broaden its range of sources.
Review of diffractive deep neural networks
Authors: Sun Yichen , Dong Mingli , Yu Mingxin , Liu Xiaolin , Zhu Lianqing
Published: September 2023

In 2018, a UCLA research group published an important paper on optical neural network (ONN) research in the journal Science. It developed the world’s first all-optical diffraction deep neural network (DNN) system, which can perform MNIST dataset classification tasks at near-light-speed. To be specific, the UCLA research group adopted a terahertz light source as the input, established the all-optical diffractive DNN (D2NN) model using the Rayleigh-Sommerfeld diffraction theory, optimized the model parameters using the stochastic gradient descent algorithm, and then used 3D printing technology to make the diffraction grating and built the D2NN system. This research opened a new ONN research direction. Here, we first review and analyze the development history and basic theory of artificial neural networks (ANNs) and ONNs. Second, we elaborate D2NN as holographic optical elements (HOEs) interconnected by free space light and describe the theory of D2NN. Then we cover the nonlinear research and application scenarios for D2NN. Finally, the future directions and challenges of D2NN are briefly discussed. Hopefully, our work can provide support and help to researchers who study the theory and application of D2NN in the future.
Timely Wildfire Perimeter Mapping for Unmanned Aerial Platforms
Authors: Rittenbach Andrew , Imes Connor , Walters John Paul
Published: September 2023

Wildfire perimeter mapping currently relies on deferred processing of data
from manned and orbital platforms using hand-tuned physics-based models. We demonstrate real-time on-board multispectral data processing on cost-efficient unmanned aerial
platforms using ML-based semantic segmentation.
Super-simplified fiber scanner for cellular-resolution endoscopic imaging
Authors: He Lu , Li Xijie , Yang Jie , Jiang Longjie , Liu Qian , Fu Ling
Published: September 2023

Fiber scanners are portable and miniaturized laser scanning devices used for a wide range of applications, such as endoscopic probes for biomedical imaging. However, in order to achieve different resonant frequencies for 2D actuation, existing fiber scanners have complex actuation mechanisms and structures, resulting in being an obstacle for endoscopic imaging. By exploiting the intrinsic difference in bending stiffness of non-symmetrical fibers, we present the most simplified fiber scanner to date, containing only a single piezoelectric bimorph and a single non-symmetrical fiber with a 1D actuator for 2D laser scanning. 5-fps (frames per second) Lissajous scan is achieved with a scanning range of >300  μm and a driving voltage of ≤10V
pp
. The ultra simplified structure of the fiber scanner enables a miniaturized optical probe with a diameter of 1.9 mm, and image quality comparable to that of commercial microscopes. Taking advantage of its ease of manufacture and low cost, the fiber scanner offers a transformative way forward for disposable endoscopic probes that avoid the risk of cross infection during endoscopic inspections.
Exploring the association between health, local area characteristics and climate action plans in the UK: Cross-sectional analysis using administrative data from 2018 and a citizen science ranking of climate action plans from 2021
Authors: Brown Heather , Butterfield Scott , Davies Jessica , Dodd Steven , Morris Abigail
Published: September 2023

Local government has an important role to play in mitigation and adaption to climate change. In the UK, 82% of all emissions fall within the scope of local government. However, in UK climate legislation there is no statutory requirement for local government to address climate change. Eighty percent of local authorities have declared a climate emergency and developed climate action plans. The aim of this study is to explore the association between social vulnerability (poor health, financial resources, deprivation, house prices) and the quality of climate action plans as measured by a scorecard system created by Climate Emergency UK. We hypothesis that areas with lower levels of social vulnerability will have higher quality climate plans. We utilised a citizen science created dataset ranking local government’s climate action plans and administrative data on local area characteristics related to social vulnerability at the local authority level. Descriptive analysis and multivariate regression were employed. We found a very small but significant association between total weighted score, central government funding and average house prices. For the individual dimensions of the quality of climate action plans, higher male life expectancy and house prices were associated with better commitment and integration and having a greater percentage of the population over the age of 65 was associated with a lower score in this dimension. More urban areas and less deprived areas had higher scores for planning climate education, skills and training. We suggest that greater national guidance is needed including sharing good practice on how to build community support and additional funding for climate change mitigation/adaption in particular for education, skills, and training in more deprived areas may help to prevent variations in climate action plans increasing inequalities.
Acceptability of using mobile Health (mHealth) as an intervention tool for people with drug use disorders in Tanga, Tanzania
Authors: Munishi Castory , Ndumwa Harrieth P. , Massawe Josephine E. , Njiro Belinda J. , Ngowi Jackline , Suhartono Sanita , Busse Anja , Campello Giovanna , Garofalo Giovanna , Cipolla Pietro , Nyandindi Cassian , Ubuguyu Omary , Sunguya Bruno
Published: September 2023

Evidence on the additional benefit in treatment and recovery process among PWDUD using digital health interventions is lacking. This study aimed to describe the acceptability of using a digital intervention to increase information access for PWDUD in Tanga region, Tanzania. This study was conducted among 465 participants in Tanga, a coastal region on the Northeast of Tanzania has the second highest number of PWDUD in Tanzania. This cross-sectional descriptive study used both quantitative and qualitative approaches. The majority of the PWDUD 67.6% do not own mobile phones. Out of the 156 participants with mobile phones, only 6.4% owned a smartphone. Most of the participants, 83.6%, reported living with someone who owns a mobile phone. Importantly, a significant number of participants, 98.5% from both areas showed readiness to use mobile phones to access information about the harmful use of substance and substance use disorder treatment options. Participants described how mobile phones can be useful to them in accessing information related to treatment and access to treatment options. The findings of this study helped to inform the target audience for the developed Huru App that should not be only PWDUD but the community at large.
Assessment of the availability of repurposed orphan drugs in India
Authors: Rajueni Khujith , Chakraborty Choudhury Mohua
Published: September 2023

India has a massive burden of rare diseases (RDs), with an estimated 96 million people living with RDs but limited options for treatment. Repurposing drugs used for other common conditions are essential alternative for RDs due to their cost-effectiveness and reduced timeline. India’s patent regime prevents the evergreening of drugs, and a large generic manufacturing industry provides ample opportunity to explore the potential of repurposed drugs for treating RDs, known as repurposed orphan drugs (ROD). However, there is no portal or other source for information on orphan drugs in India. This study assesses the availability of RODs in India through quantitative analysis. In the absence of a separate orphan drug designation in India, we consider USFDA-approved orphan-designated products as the reference. We searched USFDA-approved RODs in recognized sources in India, such as CDSCO, AYUSH gazette, FSSAI, and Indian Pharmacopeia, which provides a list of drugs approved for marketing in India. We classified the drugs into separate groups based on their record from different sources and explored the regulatory implications of the differential representations. We found that almost 76% of the USFDA-approved RODs are listed in one of the Indian regulatory bodies’ records either in the same form (61%) or in a different fixed-dose combination. For 67 drugs no information was found, these drugs have to be imported for use. Only 17 of the 43 RDs mentioned in the National Policy for Rare Diseases, matched the indications listed for approval of one of the 279 RODs identified in the study. This underscores the scarcity of RD treatment and the pressing need for accessibility in India. This information on RODs will help relevant stakeholders to efficiently manage RDs in India. The study also highlights existing gaps in Indian regulatory databases that limits access to accurate information about the availability of drugs.
Do women and men compete equally on a level playing field? An empirical investigation into the 2021 Olympic shooting competitions
Authors: Goldschmied Nadav , García-Aliaga Abraham , Muriarte Solana Diego , Mon-López Daniel
Published: September 2023

Due to physical differences between the genders, it is hard to study whether women also vary from men in their competitive drive in sports. The Olympic committee instituted major rule changes in the sport of shooting in the Tokyo Olympic Games (2021), leveling the playing field. We explored performance in a myriad of competitions including newly established mixed-gender doubles events in this unique sport of very limited physical input. Men performed better than women in events which required “dynamic” qualities (following moving targets) but when the competitions were held most constant (rifle shooting with stationary targets indoors) and regardless of distance or posture, women performed equally to men exhibiting seemingly similar competitive drive. The last finding should propel the Olympic committee to fully integrate rifle events. In the broader sense, we find that when the playing field is even, the genders, at least among highly trained selective competitors compete equally.
The impact of deep learning reconstruction in low dose computed tomography on the evaluation of interstitial lung disease
Authors: Kim Chu hyun , Chung Myung Jin , Cha Yoon Ki , Oh Seok , Kim Kwang gi , Yoo Hongseok
Published: September 2023

To evaluate the effect of the deep learning model reconstruction (DLM) method in terms of image quality and diagnostic agreement in low-dose computed tomography (LDCT) for interstitial lung disease (ILD), 193 patients who underwent LDCT for suspected ILD were retrospectively reviewed. Datasets were reconstructed using filtered back projection (FBP), adaptive statistical iterative reconstruction Veo (ASiR-V), and DLM. For image quality analysis, the signal, noise, signal-to-noise ratio (SNR), blind/referenceless image spatial quality evaluator (BRISQUE), and visual scoring were evaluated. Also, CT patterns of usual interstitial pneumonia (UIP) were classified according to the 2022 idiopathic pulmonary fibrosis (IPF) diagnostic criteria. The differences between CT images subjected to FBP, ASiR-V 30%, and DLM were evaluated. The image noise and BRISQUE scores of DLM images was lower and SNR was higher than that of the ASiR-V and FBP images (ASiR-V vs. DLM, p < 0.001 and FBP vs. DLR-M, p < 0.001, respectively). The agreement of the diagnostic categorization of IPF between the three reconstruction methods was almost perfect (κ  =  0.992, CI 0.990–0.994). Image quality was improved with DLM compared to ASiR-V and FBP.