bluuebunny/crossref_metadata_2025 huggingface dataset:
What is Meant by Land Use Change? Effects of Mining Activities on Forest and Climate Change
Authors: GENÇAY Gökçe , DURKAYA Birsen
Published: July 2022

The ownership of 99.9% of forests in Turkey belongs to the State. According to the mandatory provisions of the Turkish Constitution of 1982, the ownership of State forests cannot be transferred to third parties. However, forest legislation permits several activities within the State forests, other than forestry, under certain conditions. Thus, in this study, the legal process of mining permits granted in State forests in Turkey was analyzed, and the policies implemented in mining permits were tried to be evaluated. Then, how mining activities affect forestlands and the environment has been compared by taking international studies in the literature into account. The change in the amount of carbon stored in the forests where the land use changed as a result of the given mining permit was calculated using the Biomass Expansion Factor (BEF) method. After the mining permit was granted, 53% of the land use change occurred in the sample area, and there was a 43% decrease in the amount of carbon stored.
Potential E. coli Expression Strategies for Production of Soluble Recombinant Streptokinases
Authors: Buniya Harith k.
Published: July 2022

The expression of recombinant protein for industrial and therapeutic applications, requires high yielding expression system like E. coli, which is easier to handle and satisfactory for various purposes. On other hand, one of the limitations of this system is Inclusion bodies formation. In this study, we optimized the conditions for the expression of the soluble form for three recombinant streptokinases (FSK, KSK, and FKSK). The change in culture conditions, like optical density, post-induction temperature, inducer concentration, media, and expression host had different effects on the expression levels of hybrid streptokinase proteins. The high amount of soluble fraction for FSK protein was in LB medium at 20°C in BL21 (DE3) and GJ1158. The amount of soluble protein was approximately 50%, but the amount of total protein at 20°C was lower than other induction temperatures. The high amount of soluble protein, expressed hybrid streptokinase (KSK) in LB medium at 30°C in BL21 (DE3) hosts, 0.5 O.D. cell densities were induced in 0.5mM IPTG. Approximately 70% of protein is soluble in these conditions. FKSK was never produced as a soluble form irrespective of any change in condition. All expressed FKSK protein appeared as inclusion bodies.
Convergence Analysis of Butterfly Optimization Algorithm
Authors: Chakraborty Prasanjit , Sharma Sushmita , Saha Apu Kumar
Published: July 2022

Convergence analysis of any random search algorithm helps to verify whether and how quickly the algorithm guarantees convergence to the point of interest. Butterfly optimization algorithm (BOA) is a popular population-based stochastic optimizer introduced by mimicking the foraging behaviors of butterflies in nature. In this paper, we have developed the Markov chain model of the BOA and analyzed the convergence bahavior of the algorithm. The Markov chain model of the BOA is constituted where the population sequence generated by the algorithm is found to be a finite homogenous Markov chain and the defined population state set is found to be reducible. Convergence analysis of the algorithm is performed mathematically using the Markov chain model of the algorithm with the help of global convergence theorem which is based on a random search algorithm satisfying two subtle conditions. The butterfly algorithm has been found to satisfy the conditions for the global convergence theorem to enact, whereof it guarantees the global convergence of the BOA. We have also tried to show experimentally that the convergence of the algorithm do not always have considerable impact on rate of convergence as it is influenced by various other factors.
Development of a Mechanism for Preventing Bankruptcy of Enterprises at the Regional and National Level
Authors: Babayev Volodymyr M. , Dymchenko Olena V. , Rudachenko Olha O. , Gazzola Patrizia , Sepashvili Eka , Shkurupiy Kateryna V.
Published: July 2022

The paper develops a mechanism for preventing bankruptcy of enterprises at the regional level, which allows management to make managerial decisions on time that will effectively assess the threat of bankruptcy and anticipate it in advance. The developed research mechanism includes 3 main stages: formation of the feature space; enterprise`s bankruptcy probability assessment; forecasting the state of the enterprise.
One proved that every year most Ukrainian enterprises have insignificant incomes and receive huge losses, as a result an unemployment is growing in the country. Quarantine restrictions related to the COVID–19 pandemics have made a significant negative contribution to the activities of both domestic and foreign enterprises.
The object of the study was an international tobacco company whose activities goes in the Kharkiv region. Thus, the analysis of the financial condition showed that the enterprise investigated is not yet in danger of bankruptcy, since it is in a stable financial condition. In addition, the company has high indicators of liquidity and solvency. That is why the paper proposes to consider the mechanism for preventing bankruptcy of enterprises on the example of an international tobacco company.
Thus, as a result of the development of the bankruptcy prevention mechanism, it became possible to form the basis of models that will be adapted to domestic enterprises, which will allow identifying the threat of bankruptcy and preventing bankruptcy at an early stage, thereby increasing the number of financially healthy enterprises and economic growth in the regions.
The Role of Institutional Determinants in Overcoming the Tendency of Deindustrialization of the National Economy
Authors: Tsyplitska Olena O. , Zavgorodnia Mariia Yu.
Published: July 2022

The purpose of the research is the detection of institutional determinants and substantiation of their decisive role in the course of industry modernization that is the essential condition for national economic growth. The study relies on the logic and historical method to reveal the peculiarities of best practices of the world countries with different level of development; statistical analysis method to determine the trends of economic and institutional performance changes; methods of comparison and generalization etc. Summarizing the research, it was proved that Ukrainian manufacturing sector made still insignificant contribution, oppositely its sensitivity to economic crises caused significant imbalances in economy. However, these are state organizations and political institutions that considerably affect the revitalization of upgrading processes in industrial sector through market failure mitigation. The study found that the lack of strategic vision and long-term industrial development planning was the main institutional obstacle for activation of economic development of Ukraine. To overcome the trend of deindustrialization it was proposed to provide effective institutional interrelations between the state and stakeholders, namely to develop institutional mechanisms of modernization, which will eventually contribute to: diversification of the industrial structure of the economy towards increasing the share of medium and high-tech processing industries and raising the complexity of products; improvement of relations between research centers and enterprises, especially regarding innovation activities, commercialization of existing scientific developments; imports of scarce cutting-edge technologies.
Generator Jadwal Mengajar Dosen Dengan Perkecualian Memakai Teori Himpunan
Authors: Wijana Katon , Oslan Yetlin , Kristanto Harianto
Published: July 2022

Dosen mempunyai tugas tri darma perguruan tinggi, yaitu pengajaran, pengabdian dan penelitian, oleh sebab itu kegiatan dosen tidak semata-mata mengajar di kelas melainkan juga melakukan kegiatan-kegiatan lain sehubung-an dengan hal tersebut. Dalam hal ini ketua program studi, sebagai penyusun jadwal kuliah, hanya mengetahui mata-kuliah-matakuliah yang diampu oleh dosen yang bersangkut-an dan tidak mengetahui kegiatan lain yang dilakukan oleh dosen tersebut. Pada kasus inilah penulis ingin memakai teori himpunan untuk membuat generator jadwal yang bisa menge-cualikan dosen tertentu pada jadwal tertentu.

 

 Teori Himpunan dapat mengelompokkan mana yang merupakan himpunan bagiannya atau bukan himpunan bagiannya, dapat juga mengidentifikasi irisan dari beberapa himpunan serta dapat menggabungkan antara satu himpunan dengan himpunan yang lain. Jadwal kegiatan pada dasarnya dapat dikategorikan sebagai himpunan yang dapat di-operasikan memakai teori-teori tersebut, sehingga sangat memungkinkan untuk mengidentifikasi jadwal mana yang bertabrakan (beririsan) dan jadwal mana yang masih kosong (bukan himpunan bagiannya) untuk dosen tertentu.

 

 Dengan mengimplementasikan teori himpunan pada basis data jadwal mengajar dosen ditambah dengan pe-ngecualiannya, diharapkan akan diperoleh hasil jadwal meng-ajar dosen yang sesuai dengan jadwal pengajaran maupun dengan jadwal kegiatan dosen masing-masing.
FATORES DE EMISSÃO E DE ENRIQUECIMENTO DA CROSTA PARA ELEMENTOS TRAÇO (MP2,5) EMITIDOS PELA FROTA VEICULAR NA REGIÃO METROPOLITANA DE SÃO PAULO, BRASIL
Authors: Benatti Juan , Pérez-Martínez Pedro , Miranda Regina
Published: July 2022

EMISSION AND CRUST ENRICHMENT FACTORS FOR TRACE ELEMENTS (PM2.5) EMITTED BY THE VEHICLE FLEET IN THE METROPOLITAN AREA OF SÃO PAULO, BRAZIL. Air pollution can cause several negative impacts on health and the environment. In large urban centers, this pollution is directly related to anthropogenic activities, mainly activities in the transportation sector. This study analyzed data on black carbon, fine particulate material (PM2.5) and its main trace elements from automotive vehicles (S, P, K, V, Cr, Fe, Cu, Ni, Zn, Cd, Br and Pb), collected during a long sampling period, carried out in the Metropolitan Area of São Paulo (MASP), Brazil. The filters used were analyzed by various analytical techniques, enabling the identification of the different elements present in the samples, their respective concentrations and the main sources of these pollutants and their contributions to the sampled total. Thus, it was possible to separate the total contributions of each source and use only the contributions of anthropogenic origin to define the emission factors (EF) and the crustal enrichment factors (EFc) for the different studied pollutants. We used these factors to compare different environments/studies. We chose two studies carried out previously, also in the MASP, in the Jânio Quadros (TJQ) and Rodoanel (TRA) tunnels, and found that these tunnels are respectively 2.3 and 3.8 times more polluted than the region from our study
DESENVOLVIMENTO DE ACESSÓRIO PORTÁTIL DE CONTROLE DE TEMPERATURA PARA MEDIDAS ESPECTROSCÓPICAS
Authors: Pires Daniel , Silva Henrique , Rocha Lucas , Nassar Eduardo
Published: July 2022

DEVELOPING A PORTABLE DEVICE TO CONTROL TEMPERATURE DURING SPECTROSCOPIC MEASUREMENTS. Temperature is a natural phenomenon that may modify the structure of chemical compounds and hence their properties. We aimed to develop a simple portable system based on the Peltier principle for spectral characterization of compounds with temperaturedependent structure. The device was constructed and adapted to three pieces of equipment: X-ray diffractometer, vibrational spectrophotometer, and electronic spectrophotometer. The device was evaluated by using commercial thermochromatic inks, whose color depends on temperature. The X-ray diffraction results for the ink whose color changed at a transition temperature of 31 o C showed that the peak at 2θ = 21.6o decreased probably due to alterations in the structures of the components underlying the ink color and solvent. The absorption spectra showed reduced absorption, typical of change in color, a property that is inversely proportional to temperature. The device working range varied from 15 to 75o C, and it was constructed from parts that are easily available in the national market at an affordable price. The device can be adapted to different equipment with distinct configurations regarding the sample compartment
Deniz Suyu ve Hava Debi Oranının Toprak Isı Değiştiricili Bir Damıtma Sistemi Performansına Etkisinin İncelenmesi
Authors: HÜRDOĞAN Ertaç , GÜNEŞ Abdülkadir , KARA Osman
Published: July 2022

Bu çalışmada, nemlendirme-nem alma (NNA) teknolojisi çalışma prensibine dayalı güneş enerji destekli ve toprak ısı değiştiricili bir damıtma sistemi ele alınarak sistemin Termodinamiğin II. Yasasına göre analizleri (Ekserji analizi) yapılmıştır. Sistemde, deniz suyu önce güneş kolektörleri kullanılarak ısıtılmakta ve daha sonra nemlendiricide, dış ortamdan alınan havanın nemlendirilmesinde kullanılmaktadır. Nemi ve sıcaklığı yükselmiş olan hava, nem alıcıya gönderilerek, toprak ısı değiştiricisiyle soğutulan suyla yoğuşturularak damıtılmış (temiz) su elde edilmektedir. Çalışmada, sistemin farklı deniz suyu ve hava debi oranında (MR) çalışma durumu farklı konfigürasyonlar için değerlendirilmiştir. Elde edilen sonuçlardan, sistemde en fazla tersinmezliğin güneş kolektörlerinde meydana geldiği, sistemin ekserji veriminin farklı konfigürasyonlara göre %5 ile %22 arasında değiştiği ve MR’nin artması ile sistemin ekserji veriminin tüm konfigürasyonlar için azaldığı görülmüştür.
An Investigation on Dimensional Accuracy of 3D Printed PLA, PET-G and ABS Samples with Different Layer Heights
Authors: BOLAT Çağın , ERGENE Berkat
Published: July 2022

In this study, the effect of filament type and layer height on the dimensional accuracy of the 3D printed tensile test samples from PLA, PET-G, and ABS was investigated in depth. Based on the fused filament fabrication (FFF) technology, tensile test samples were produced with various layer heights (0.2 mm, 0.3 mm, and 0.4 mm) while the other printing parameters were kept constant, except for nozzle and building platform temperature. Length, width, and height values of the produced test samples were measured, and obtained results were compared with design dimensions to observe the dimensional accuracy of each sample. Also, surface roughness measurements were performed on the samples to examine their final surface quality. From dimensional measurements, it was seen that the most accurate results were recorded for PET-G (in length and height) and PLA (in width) samples. Furthermore, the best surface quality was attained in PLA samples compared to other filaments.
Fotovoltaik Bir Panelin Matlab@Simulink ile Modellenmesi ve Dış Ortam Koşullarındaki Davranışının İncelenmesi
Authors: ALADAĞ İlyas , YANIKTEPE Bület
Published: July 2022

Temiz ve yenilenebilir enerji kaynaklarından biri olan güneş enerjisi sera gazı emisyonu oluşturmaması, sınırsız kaynak potansiyeli ve kaynak erişilebilirliği gibi olumlu etkileri nedeniyle sıklıkla tercih edilmektedir. Bu nedenle ülkemizde güneş enerjisi santrallerinden elektrik üretimi oldukça yaygındır. Güneş enerjisinden elektrik üretimi, fotovoltaik (FV) hücrelerin güneş ışınımını elektrik enerjisine dönüştürmesi ile gerçekleşmektedir. Bu çalışmada Matlab@Simulink yazılımında modellenen monokristal (c-Si) yapıdaki bir FV panelin laboratuvar ve dış ortam koşullarındaki davranışları karşılaştırılmıştır. Daha sonra Osmaniye Korkut Ata Üniversitesi Mühendislik Fakültesi çatısına kurulan sistem ile dış ortam koşullarında bulunan FV panelin performans sonuçları incelenmiştir. Elde edilen sonuçlara göre model ve deneysel sistemin birbirleriyle uyumlu olduğu gözlemlenmiştir.
Numerical Study on the Ballistic Performance of Twaron®/Epoxy Laminated Composite Plates Manufactured by Vacuum Assisted Resin Infusion Moulding Against 9 mm Bullet Threat
Authors: DEMİRCİOĞLU Tayfur Kerem , BALIKOĞLU Fatih
Published: July 2022

This article presents the experiments on the ballistic effect of plates formed by stacked Twaron® fabrics between 10 and 16 layer numbers impregnated with epoxy resin by vacuum infusion method and the results of Autodyn-2D® simulations using an axisymmetric model. The ballistic impact resistance of the panels produced was determined according to the NIJ-STD-0108.01 standard. All panels were tested against 9 mm FMJ bullets at an average velocity of 390 m/s with the MP5 gun for armour application. The interaction of the plates with the bullet, the post-shot damage photographs, residual velocities of the bullet were compared with Autodyn-2D® simulations. Parametric study was performed in the analysis to determine the optimum bullet velocity, layer thickness and tensile failure strain. It was observed that the data obtained from the simulations were consistent with the experiments.
Biyogazla Birlikte Oluşan Diğer Ürünlerin Araştırılması
Authors: SARIBIYIK Oğuz Yunus
Published: July 2022

Gelişmekte olan ülkelerin enerji tüketimindeki yükselme atmosfere karbondioksit salınımını artırarak küresel ısınmaya sebep olmaktadır. Küresel ısınmaya bağlı olarak ortaya çıkan doğal afetler insanların yaşamlarını olumsuz yönde etkilediklerinden dolayı atmosfere karbondioksit salınımının kontrol altına alınıp sürdürülebilir hale getirilmesi gerekmektedir. Bu sebeple fosil kökenli yakıtlara alternatif kaynaklarının araştırılması zorunlu hale gelmektedir. Rüzgâr enerjisi, biyodizel vb. gibi alternatif biyoyakıtlar içerisindeki alternatif enerji üretim yöntemlerinden birisi de biyogaz üretimidir. Biyogaz üretiminde uygun organik atıklar kullanılarak %35-45 CO2, %55-65 CH4 oranlarda biyogaz karışımı üretilirken eser miktarda CO, H2S, NH3 gibi diğer ürünlerde ortaya çıkmaktadır. Yapılan bu çalışmada biyogaz üretiminde kullanılan sıvı fazda bulunan toplam karbon miktarı, fenolik içerik miktarları, Azot(N), Fosfor(P2O5), Potasyum(K2O), pH, Hümik asit, Fülvik asit ve iletkenlik gibi değerlerin değişimi biyogaz üretimi öncesi ve sonrasında test edilerek belirlenmiştir. Elde edilen sonuçlara göre N, P, K miktarlarında herhangi bir değişim ortaya çıkmazken pH değerinde yükselme, fenolik içerik, toplam karbon içeriği, iletkenlik, Hümik ve Fülvik asit içeriklerinde biyogaz üretim süreci

sonrasında artış meydana geldiği gözlemlenmiştir.
Bazı Bitki Kaynaklarının Farklı Çözgenlerde Hazırlanan Ekstrelerinin Antimikrobiyal Aktivitesinin Araştırılması
Authors: SANCAR BEŞEN Burcu , EREN KARAHAN Leyla , PARLAKYİĞİT Pınar , KIRILMIŞ Cumhur , ERDOĞAN Sakine
Published: July 2022

Bu çalışmada, aloe vera (Aloe barbadensis), aynısefa (Calendula officinalis), baldırıkara (Adiantum capillus-veneris Linn.) ve kudret narı (Momordica charantia) bitkileri gibi bazı bitki kaynaklarının farklı çözgenler kullanılarak hazırlanan ekstrelerinin antimikrobiyal aktivitesinin araştırılması amaçlanmıştır. Bu amaçla, bitkilerin n-hegzan, etanol, metanol ve distile su içerisinde maserasyon yöntemi ile ekstreleri hazırlanmış ve hazırlanan ekstrelerinin, Staphylococcus aureus ve Escherichia coli bakterilerine karşı antibakteriyel; Aspergillus niger mantarına karşı antifungal aktivitesi incelenmiştir. Çalışma sonuçları, ekstraksiyonda kullanılan bitki kaynağının ve çözgen türünün ekstrelerin antimikrobiyal aktivitesi üzerinde oldukça önemli olduğunu ortaya koymuştur.
Evaluation of climate change effects on flood frequency in arid and semi-arid basins
Authors: Shokouhifar Yasaman , Lotfirad Morteza , Esmaeili-Gisavandani Hassan , Adib Arash
Published: July 2022

Climate change (CC) will increase the intensity of extreme phenomena such as drought and flood in arid and semi-arid regions. This will cause the water supply of these areas to become very difficult in times of crisis. This study identifies sub-basins with high flood potential in the baseline period (1982–2005) and the future period (2025–2048) in the Hablehroud basin, north-central Iran. It uses the soil and water assessment tool (SWAT) and 23 coupled model intercomparison project 5 (CMIP5) general circulation models (GCMs). It estimates the instantaneous peak flow (IPF) and uses a flood index (FI) to determine the contributions of each sub-basin to the floods. The rainfall of the basin will increase by 11.5% under representative concentration pathway (RCP) 4.5 and 12.6% under RCP 8.5. The minimum daily temperature (Tmin) of the basin will increase by 0.8 °C under RCP 4.5 and 1.1 °C under RCP 8.5 in the future period. In addition, the maximum daily temperature (Tmax) will rise by 1 °C under RCP 4.5 and 1.2 °C under RCP 8.5. Moreover, basin runoff will increase by 6.4% under RCP 4.5 and 11.6% under RCP 8.5. The results indicate that the central and southern sub-basins made the most significant contribution to floods in the baseline period, while the eastern sub-basins will make the most considerable contribution to future floods.
Relationship between the molecular structure of different dithiocarbamates and their oil removal performance
Authors: Hao Ziyang , Zhang Wenyan , Chen Wu , Mei Ping , Lai Lu
Published: July 2022

Six kinds of dithiocarbamates (DTCs) were synthesized from three linear amines with different amino numbers, two polyether amines with different molecular weights, and one branched amine with benzene rings, respectively. The conditions affecting oil removal rate and floc rising time of DTC were studied using simulated oily wastewater. Furthermore, the effects of the molecular structure of DTC on oil removal efficiency, floc morphology, floc rising time, and floc adhesion were investigated. When the conditions were optimal, the oil removal efficiency of DTC synthesized from polyethylene polyamine was 95.14%, which was higher than other DTCs. Meanwhile, the ferrous ion was the most suitable chelating metal ion for DTC than other transition metal ions. The increase of amino groups in the initiators improves the oil removal efficiency of DTC, while the linear structural DTC exhibits a low oil removal efficiency due to a lack of network structural flocs. The introduction of polyether structure helps reduce the volume of the flocs and make them compact, but it also increases the adhesion of the floc on the metal surface. The introduction of bisphenol A phenol amino resin structure induces the generation of the flocs in oil wastewater and improves the oil removal efficiency.
Prognostic Value of Pericardial Effusion Size in Patients with Acute Heart
Failure
Authors: Zhai Guangyao , Zhang Biyang , Wang Jianlong , Liu Yuyang , Zhou Yujie
Published: July 2022

Background:

Pericardial effusion (PEf) can occur with acute heart failure (AHF).

Objective:

To evaluate the effect of PEf size on the prognosis of patients with AHF.

Method:

According to the maximum size of PEf, all patients were divided into five groups. The primary
outcome was in-hospital mortality. The independent effect of PEf size was determined by binary
logistic regression analysis. The curve in line with the overall trend was drawn by local weighted regression
(Lowess).

Result:

We included 192 patients with AHF complicated by PEf. As PEf size increased, in-hospital
mortality increased significantly (Group 5 vs Group 1: 34.8 vs 8.9% p=0.042). After adjusting for confounders,
there was no significant association between PEf groups and in-hospital mortality (Group 5 vs
Group 1: odd ratio (OR), 95% confidence interval (CI): 2.72, 0.41-18.22, p=0.298). However, when PEf
size was analysed as a continuous variable, an independent association between increased risk of inhospital
mortality and PEf size was observed (OR, 95% CI: 1.08, 1.00-1.16, p=0.037). The Lowess
curve showed a positive relationship between PEf size and in-hospital mortality. Furthermore, as PEf
groups increased, the length of hospital stay (Group 5 vs Group 1 median and interquartile range: 16,
14-21 vs 13, 8-17 days, p<0.001) was significantly prolonged. An association between PEf size with
acute kidney injury (AKI) was not observed.

Conclusion:

The PEf size was independently associated with the increased risk of in-hospital mortality
in patients with AHF.
Diagnostic Value of Ultrasound Elastography in the Differentiation of Breast Invasive Ductal Carcinoma and Ductal Carcinoma In situ
Authors: Shi Jian , Chen Luzeng , Wang Bin , Zhang Hong , Xu Ling , Ye Jingming , Liu Yinhua , Shao Yuhong , Sun Xiuming , Zou Yinghua
Published: July 2022

Background:

Ultrasound elastography (US-E) has been shown superior to conventional US in the diagnosis of benign and malignant breast lesions. In contrast, the role of US-E in the differentiation of breast invasive ductal carcinoma (IDC) and ductal carcinoma in situ (DCIS), has been poorly described.

Objective:

This study was designed to examine the diagnostic value of US-E in the differentiation of IDC and DCIS.

Methods:

Medical records of all patients who underwent preoperative US-E evaluation, and diagnosed with IDC or DCIS at our hospital during April-December 2019 were retrieved and analyzed. Those who had prior surgical treatment, chemotherapy or radiotherapy were excluded.

Results:

Twenty women with DCIS and 111 women with IDC were included in this study. There were no significant differences in age, maximum lesion diameter and tumor volume between the two groups. While shear wave velocity (SWV) inside the lesion and in the surrounding tissue, strain ratio and tumor area ratio were not substantially different between the two groups, SWV at the edge of the lesion was significantly higher in IDC cases, which had an AUC value of 0.66 with a sensitivity of 65.8% and a specificity of 60.0% for the differential diagnosis of IDC and DCIS.

Conclusion:

Edge SWV is significantly higher in IDC than that in DCIS, which had a moderate diagnostic value for the differentiation of IDC and DCIS, similar to the perfomance of diffusion-weighted magnetic resonance imaging as reported in the literature. In terms of cost-effectiveness, US-E could be very useful while waiting for further evaluations to determine whether US-E combined with other diagnostic modalities improves the diagnostic performance.
Synthesis and Ready to Use Kit Formulation of EDTMP for the
Preparation of 177Lu-EDTMP as a Bone Palliation Radiopharmaceutical
Authors: Mercanoglu Guldem , Zilbeyaz Kani , Arslan Nuri
Published: July 2022

Introduction:

With its suitable nuclear decay characteristics and large-scale production feasibility with adequate specific activity, 177Lu is regarded as an excellent radionuclide for developing bone pain palliation agent. Ethylenediamine-tetramethylenephosphonic acid (EDTMP) is a preferred carrier molecule for radiolanthanides such as 177Lu. The present paper describes the synthesis of EDTMP and the development of a ready-to-use kit for the preparation of 177Lu-EDTMP and its quality control in accordance with the quality and safety criteria required for medicinal use.

Material and Methods:

EDTMP was synthesized by a modified Mannich-type reaction and the structure was characterized using NMR and IR spectroscopy. Optimization of radiolabeling conditions were carried out with two different salt forms of EDTMP. The labeling yield was checked by paper chromatography with radiation detection. Kit was developed as a lyophilized mixture of EDTMP and sodium bicarbonate in a maximum volume of 5 mL. Labeling efficiency, radionuclidic purity, radiochemical purity, sterility, and pyrogenity analysis were performed as the quality control of the labeled kit.

Results:

The analytical data for the structure determination and purity of the synthesized ligand were in agreement with commercial authentic samples used in radiopharmacy.177Lu-EDTMP complex was prepared using synthesized EDTMP ligand under optimized labeling conditions with high labelling yield (>99%). The radiolabeling yields of the EDTMP kit at room temperature after 30 min and 48 hours were 99.46% and 99.00%.

Conclusion:

The developed EDTMP kit enables an instant one-step preparation of the radiopharmaceutical of high radiochemical purity (>99%) and has a sufficiently long shelf life. This enables the routine production of the 177Lu-EDTMP in nuclear medicine clinics without requiring experienced staff.
Veronica Stigger e o espírito de 22
Authors: Sales Paulo Alberto da Silva
Published: July 2022

Desenvolve-se uma reflexão em torno dos procedimentos de escrita de Veronica Stigger, que revitalizam na contemporaneidade brasileira os experimentalismos e as transgressões instauradas a partir da Semana de 22. Sua obra ficcional apresenta uma dicção fragmentada, humorística, intertextual, intersemiótica, irô-nica, paródica e transgressora que segue a esteira dos manifestos e de outros textos de Oswald de Andrade publicados tanto na revista Klaxon (1922) quanto nos anos conseguintes, tais como Manifesto da poesia pau Brasil (1924), Memórias sentimentais de João Miramar (1924), Poesia Pau Brasil (1925), Manifesto Antropófago(1928) e Serafim Ponte Grande (1933), bem como dos Movimentos modernistas do Brasil (1922-1928) e Cobra Norato (1931) de Raul Bopp. Por meio da leitura de Opisanie swiata (2013), examina-se como Stigger reverbera o espírito de 22, sobretudo por meio da apropriação de elementos ficcionais e biográficos de Oswald, Mário, Bopp e Tarsila ao mesclá-los e reinseri-los em novos contextos de escrita na perspectiva da literatura pós--autônoma.
Afinidades Eletivas entre "Café", de Mário de Andrade, e "Massa-Homem", de Ernst Toller
Authors: Flory Alexandre Villibor , Protazio Beatriz Yoshida
Published: July 2022

O presente trabalho tem o objetivo de apresentar um diálogo produtivo entre a ópera-coral Café, de Mário de Andrade, escrita entre 1933 e 1942, e a peça expressionista Massa-homem, de 1919, de Ernst Toller, to-mando como base o materialismo histórico dialético. O artigo parte da perspectiva da primazia da obra de arte para a análise literária, mobilizando questões teóricas e críticas para fazer falar as obras, avaliando como se dá a formalização estética de questões sociais em cada contexto e valorizando a mediação entre arte e sociedade. O resultado disso foi o encontro de pontos de toque formais entre os dois objetos, por exemplo, que a renovação estética do texto dramático e da cena se articulam com as transformações e novas formas sociais de organização no Brasil e na Alemanha.
Rasga o coração
Authors: Wisnik José Miguel
Published: July 2022

Iniciada há cem anos, a Semana de Arte Moderna de 22 extrapolou os contornos paulistas para tornar-se marco da vida brasileira no século 20. O embate de suas potências e limitações prefiguraram os impasses da instauração do moderno por aqui, nas artes e na sociedade, o que se manifesta hoje em um Brasil espremido entre a grandeza e a barbárie.
Resilience Enhancement Online Training for Nurses (REsOluTioN): Protocol for a Pilot Randomized Controlled Trial
Authors: Srikesavan Cynthia , Davey Zoe , Cipriani Andrea , Henshall Catherine
Published: July 2022

Background

Globally, nurses are facing increased pressure to provide high-quality complex patient care within environments with scarce resources in terms of staffing, infrastructure, or financial reward. The strain and demand on the psychological health and well-being of nurses during COVID-19 has been substantial, with many experiencing burnout; as such, interventions to enhance resilience within the workplace are required. A face-to-face resilience enhancement training program for nurses that was effective in improving resilience levels was translated into a 4-week online training program, Resilience Enhancement Online Training for Nurses (REsOluTioN), to enable greater accessibility for nurses.

Objective

This study aims to compare levels of resilience, psychological health, and well-being in nurses before and after the online resilience training compared to a wait list control group. It will also explore participants’ engagement with the trial and their acceptability of the online training.

Methods

This is a two-arm, parallel, randomized controlled trial with a 6-week follow-up period. Up to 100 registered nonagency nurses working at a National Health Service hospital trust in South England will be recruited. Four cohorts will run, and participants will be randomized into a wait list control group or to REsOluTioN. Pre- and postonline surveys will collect study outcome measure data. In the REsOluTioN arm, data will be collected on the perceived usefulness of the online training via an online survey. Institutional and health research authority approvals have been obtained.

Results

REsOluTioN will aim to empower nurses to maintain and enhance their resilience while working under challenging clinical conditions. The online training will be interactive with input from mentors, health care leaders, and peers to promote engagement and enhanced communication, and will create a forum where nurses can express their views and concerns, without hierarchical infrastructures inhibiting them. This can increase self-knowledge and learning around workplace resilience coping strategies and provide a safe space to validate feelings through mentorship and peer support. Findings will be reported in accordance with the CONSORT (Consolidated Standards of Reporting Trials) guidelines. The trial is now finished and was conducted between August 2021 and May 2022.

Conclusions

The REsOluTioN trial will enable preliminary data to be gathered to indicate the online training’s effectiveness in enhancing nurses’ resilience in the workplace, with the potential for larger scale follow-up studies to identify its value to nurses working across a range of health care settings.

Trial Registration

ClinicalTrials.gov NCT05074563; https://clinicaltrials.gov/ct2/show/NCT05074563

International Registered Report Identifier (IRRID)

DERR1-10.2196/37015
Key Stakeholder Barriers and Facilitators to Implementing Remote Monitoring Technologies: Protocol for a Mixed Methods Analysis (Preprint)
Authors: Iqbal Fahad Mujtaba , Joshi Meera , Khan Sadia , Wright Mike , Ashrafian Hutan , Darzi Ara
Published: July 2022

BACKGROUND

The implementation of novel digital solutions within the National Health Service has historically been challenging. Since the start of the COVID-19 pandemic, there has been a greater push for digitization and for operating remote monitoring solutions. However, the implementation and widespread adoption of this type of innovation have been poorly studied.

OBJECTIVE

We aim to investigate key stakeholder barriers and facilitators to implementing remote monitoring solutions to identify factors that could affect successful adoption.

METHODS

A mixed methods approach will be implemented. Semistructured interviews will be conducted with high-level stakeholders from industry and academia and health care providers who have played an instrumental role in, and have prior experience with, implementing digital solutions, alongside the use of an adapted version of the Technology Acceptance Model questionnaire.

RESULTS

Enrollment is currently underway, having started in February 2022. It is anticipated to end in July 2022, with data analysis scheduled to commence in August 2022.

CONCLUSIONS

The results of our study may highlight key barriers and facilitators to implementing digital remote monitoring solutions, thereby allowing for improved widespread adoption within the National Health Service in the future.

CLINICALTRIAL

ClinicalTrials.gov NCT05321004; https://clinicaltrials.gov/ct2/show/NCT05321004
Auto Insurance Claim System for Farmers
Authors: i S G Prof. Geethanajal
Published: July 2022

Abstract: Natural disasters such as droughts, floods, cyclones, and animal attacks commonly impair agriculture production and farm revenue in India. Contract farming and futures trading are two contemporary examples of procedures that are Price changes are expected to provide some protection, either explicitly or implicitly. Agricultural protection, on the other contrary, is considered a necessary tool for efficiently addressing the risk of output and revenue loss caused by a variety of natural and artificial disasters. For the benefit of farmers, the GOI (Government of India) has implemented a number of agricultural programmes around the country. Information about various government agricultural programmes is now available on the internet in the form of websites and mobile apps, thanks to advances in technology and internet services.
Predictores de respuesta terapéutica del estado migrañoso en una sala de infusión
Authors: Rojas Villegas Yessika Milena , González María Alejandra , Puerta Martínez David , Vélez Maria Camila , Hernández Beltrán Natalia
Published: July 2022

INTRODUCCIÓN:
El estado migrañoso es una complicación de la migraña, los pacientes a menudo son hospitalizados para estudios diagnósticos o tratamiento. Una alternativa para el manejo son las salas de infusión, lo que permite minimizar los ingresos hospitalarios y la realización de exámenes innecesarios.

OBJETIVO:
Determinar la respuesta terapéutica y los factores asociados con esta en pacientes con estado migrañoso tratados en una sala de infusión.

METODOLOGÍA:
estudio de cohorte retrospectiva cuya población fueron pacientes con estado migrañoso atendidos en sala de infusión entre febrero y agosto del 2019. La información sobre variables sociodemográficas, variable clínicas y el manejo terapéutico se obtuvo a partir de la revisión de historias clínicas. Se evaluó la respuesta con escala análoga del dolor al inicio y al final del tratamiento; los pacientes con mejoría mayor al 50 % se consideraron respondedores. Se evaluaron los factores predictores de la respuesta terapéutica mediante regresión logística.

RESULTADOS:
Se incluyeron 124 pacientes, con promedio de edad de 36 (DE = 12) años, de los cuales el 82,3 % fueron mujeres. La duración promedio del estado migrañoso fue 8 (DE = 4) días, el 73,4 % de los casos se presentó sin aura y 97 (78,2 %) fueron respondedores. Los factores predictores de buena respuesta fueron el uso de dexametasona (OR 4,3) y no usar lidocaína (OR 6,0).

CONCLUSIONES:
La mayoría de los pacientes tuvo buena respuesta, lo que sugiere que las salas de infusión constituyen una buena alternativa al manejo intrahospitalario de la migraña. En nuestra experiencia, el esteroide constituye parte fundamental del manejo del estado migrañoso una vez se ha instaurado.
Tumores encefálicos asociados con epilepsia: una serie de casos
Authors: Núñez-Herrera Edgar , Núñez-Villadiego Julissa , Peña-Pinzón Sebastián , Albarracín-Albarracín Yesenia
Published: July 2022

INTRODUCCIÓN:
Las crisis epilépticas son la manifestación clínica inicial en un 30-50 % de los pacientes con tumores cerebrales. Algunos de los tumores más frecuentes, como los gliomas y los meningiomas se asocian con manifestaciones epilépticas. En el país no hay estudios que especifiquen cuáles son los tumores del encéfalo más frecuentemente relacionados con epilepsia.

OBJETIVO:
Determinar los tumores del encéfalo más frecuentes relacionados con epilepsia en pacientes del hospital Universitario Erasmo Meoz, en Cúcuta, Colombia entre los años 2015 y 2018.

METODOLOGÍA:
Estudio retrospectivo. Se recolectaron historias clínicas de pacientes mayores de 18 años que ingresaron al servicio de Neurocirugía del Hospital Universitario Erasmo Meoz, en Cúcuta, Colombia con diagnóstico de tumor del encéfalo entre el año 2015 y el 2018.

RESULTADOS:
Se incluyeron 220 historias, el 56 % correspondió al sexo femenino y la media de edad fue de 48 años; 98 (45 %) de los casos presentó crisis epilépticas. El tumor del encéfalo más frecuente relacionado con epilepsia fue el glioma (46 casos). El tipo de glioma que más se relacionó con crisis epilépticas fue el glioblastoma (27 casos); 82 % de los gliomas de bajo grado se manifestaron con epilepsia, y 71 % de los de alto grado (70,6 %). En los hombres el tumor más frecuente relacionado con epilepsia fue el glioblastoma y en las mujeres el meningioma. La localización tumoral más frecuente fue la región frontal (27 %).

CONCLUSIONES:
Los gliomas son el tipo de tumor cerebral más común relacionado con epilepsia, siendo el glioblastoma el tumor más frecuente de este grupo.
Encefalopatía asociada a enfermedad tiroidea autoinmune: reporte de caso y revisión de la literatura
Authors: Villa-Tobón Felipe , Soto-Osorio María Camila , Jiménez-Villegas Juliana , Giraldo Tapias Lilliana María
Published: July 2022

INTRODUCCIÓN:
La encefalopatía asociada a enfermedad tiroidea autoinmune se caracteriza por un inicio insidioso de síntomas neuropsiquiátricos que incluyen alteración de la función cognoscitiva, cambios del comportamiento, crisis convulsivas y trastornos del movimiento.

REPORTE DE CASO:
Hombre de 69 años con antecedente de hipotiroidismo primario que consultó por dos semanas de alteración de la memoria, confusión y trastorno del lenguaje, asociados a hiperreflexia y temblor generalizado. Los estudios mostraron nivel de hormona tiroidea y títulos de anticuerpos antitiroideos elevados, líquido cefalorraquídeo con aumento de proteínas y anticuerpos antineuronales negativos, neuroimagen normal y electroencefalograma con alteraciónes inespecíficas. Posterior a descartar otras etiologías, se hizo el diagnóstico de encefalopatía asociada a enfermedad tiroidea autoinmune y se inició manejo con esteroides, con los que presentó una mejoría clínica significativa.

DISCUSIÓN:
La encefalopatía asociada a enfermedad tiroidea autoinmune es un trastorno complejo que requiere un diagnóstico oportuno y rápido. En todos los pacientes con síntomas neuropsiquiátricos agudos o subagudos, y sin causa clara, es pertinente solicitar un perfil de anticuerpos antitiroideos independiente de la función tiroidea basal.
Emergence of a New Paradigm of Family Policy in the Context of the Global Crisis
Authors:   Russian Presidential Academy of National Economy and Public Administration, Yakovlev L.S.
Published: July 2022

The article raises the problems of theoretical and methodological substantiation of the new family policy paradigm. Based on the genetic, structural and comparative analysis of the current systems of family policy, its internal contradictions are revealed. A critical analysis of the components, modern discourses of the family, campaigns, is carried out, leading to the conclusion about their methodological one-sidedness. The variability of the forms of the modern family is substantiated, and the targeting of family policy as well as the strategy of its integration into demographic policy are reviewed.
Student Behavior in Digital Economy and Innovation Activity
Authors:   Russian Presidential Academy of National Economy and Public Administration, Avdeeva E.S.
Published: July 2022

The processes of innovation activity and readiness of university graduates to form the modern society are considered. To solve the main contradictions associated with these processes, the author proposes to use the concept of lean production as applied to the system of university training and presents a system of values for consumers of university services, identifying the main problematic points for consumers and teachers in the course of training.
Changes in the Format and Content of News in Digital Space
Authors:   Russian Presidential Academy of National Economy and Public Administration, Zazaeva N.B. , Fedyunina S.M. ,   Russian Presidential Academy of National Economy and Public Administration
Published: July 2022

The article deals with the main trends of changing news in digital space. Based on the content analysis of news feeds in Google mobile, conclusions on the main features of fake news are drawn. The authors state that the spread of such fake news leads to the devaluation of the news in the eyes of mass audience, and it ceases to be considered as an important source of knowledge about the world.
Ethnic Complementarity: An Unexplored Factor of the Ethnopolitical Process
Authors:   Russian Presidential Academy of National Economy and Public Administration, Khlystunov S.Yu. , Ivanchenko V.N. ,   Russian Presidential Academy of National Economy and Public Administration
Published: July 2022

The authors analyze the ethnopolitical process, a phenomenon that is a unique combination of primordial and constructivist factors. As a result of the conducted research, the authors came to the conclusion that it is the mode of ethnic complementarity that predetermines either the evolutionary or revolutionary form of the ethnopolitical process, as well as the depth and intensity of ethnopolitical conflicts.
The role of women on board of directors and firm performance: Evidence from Saudi Arabia financial market
Authors: Al-Matari Ebrahim Mohammed , Alosaimi Mushari Hamdan
Published: July 2022

The major purpose of this article is to investigate how women on boards of directors influence firm performance in Saudi Arabia firms. The major approach utilized to assess the influence of female board members and top management positions on business performance was multivariate regression analysis. The research employed an alternate proxy assessment for women on the boards of directors and in top management. Women on boards of directors and in top management had a modestly favourable link with company success, according to the data. The study employed alternative proxy metrics for women on the board of directors and in upper management. The study contributes to the corpus of information on the influence of women on business boards of directors and in top management. The study’s shortcomings include its small sample of publicly traded Saudi firms and its concentration on the problem of women on boards of directors and in top management in Saudi Arabia, as well as their impact on firm performance. Finally, this study is the first to examine the link between the success of a corporation and the presence of women in senior management positions and on corporate boards
Recent Trends toward Privacy-preservation in IoT, its Challenges and Future Directions
Authors: Yaraziz Mahdi Safaei , Jalili Ahmad , Gheisari Mehdi , Liu Yang
Published: July 2022

The Internet of Things (IoT) is a self-configuring, intelligent system
in which things connect to the Internet and communicate with each other.
As “things” are autonomous and rely on a significant amount of
autonomy to carry out their individual and collective tasks, it is
possible that the autonomous environment of IoT may raise privacy
concerns. IoT encounters significant privacy and security challenges,
including inaccurate device updates, a lack of efficient privacy
solutions, user unawareness, and famed active device monitoring
capabilities. In this paper, the authors describe the background of IoT
systems and privacy and security measures, (a) approaches to preserving
privacy in IoT-based systems, (b) existing privacy solutions, and (c)
recommending privacy models for different layers of IoT applications.
Based on the results of our study, it is clear that new methods such as
Blockchain, Machine Learning, Data Minimization, and Data Encryption can
greatly impact privacy issues to ensure security and privacy. Moreover,
it makes sense that users can protect their personal information easier
if there is less data to collect, store, and share by smart devices.
Thus, the use of Data Minimization methods in these networks can be very
beneficial for privacy-preserving, which is useful to route researchers
to
Solution of conformable Laguerre and associated Laguerre equations using Laplace transform†
Authors: Rabei Eqab , Al-Jamel Ahmed , Al-Masaeed Mohamed
Published: July 2022

In this paper, the conformable Laguerre and associated Laguerre
differential equations are solved using the Laplace transform. The
solution is found to be in exact agreement with that obtained using the
power series method. In addition some properties and some recursion
relations of the Laguerre and associated Laguerre functions are
discussed and proved. Then, the conformable Rodriguez’s formula and
generating function are propose