bluuebunny/crossref_metadata_2025 huggingface dataset:
Exhaled Breath Analysis in Diagnostics of Cardiovascular Diseases
Authors: Bykova A. A. , Malinovskaya L. K. , Chomakhidze P. Sh. , Trushina O. V. , Shaltaeva Y. R. , Belyakov V. V. , Golovin A. V. , Pershenkov V. S. , Syrkin A. L. , Betelin V. B. , Kopylov Ph. Yu.
Published: July 2019

Exhaled breath analysis is a novel tool for diagnostics of different diseases. Taking into account the secretory function of the lungs, the composition of exhaled breath is different in physiological and pathological conditions. In this review we consider of some substances which content vary in cardiovascular diseases – pentane, isoprene, carbon monoxide and trimethylamine. Modern technologies allow to move the analysis of exhaled breath from research laboratories into clinical practice. Thus, a new tool for real time of screening various cardiovascular diseases has appeared in the arsenal of physicians.
Specific Features of the Course of Acute Coronary Syndrome in Patients with Newly Developed Atrial Fibrillation in Clinical Practice According to the Data of the Register of Acute Coronary Syndrome
Authors: Tatarintseva Z. G. , Kosmacheva E. D. , Raff S. A. , Kruchinova S. V. , Porkhanov V. A.
Published: July 2019

Aim: to elucidate risk factors of development of atrial fibrillation (AF) in patients with acute coronary syndrome (ACS), and to assess of patient’s adherence to oral anticoagulant therapy (OAT) during 12 months after ACS episode according to the data of the Total ACS Registry for the Krasnodar Territory.

Materials and methods. In this retrospective analysis we used Registry data on patients with ACS and concomitant AF, consecutively admitted to cardiological departments of the S.V. Ochapovsky Territorial Clinical Hospital from 20/11/2015 to 20/02/18. Number of patients in the analyzed group was 201 (52 with AF which first appeared in connection with the index ACS). Survivors after hospital discharge were contacted by telephone and at planned visits. The analysis included assessment of rates of the following outcomes: inhospital death, hemorrhagic and thromboembolic complications, prognostic efficacy of the CRISADE and HAS BLED scores, and expediency of prescription to patients with ACS and concomitant first AF episode of prolonged OAT after hospital discharge.

Results. Demographic and anamnestic data of patients with the first AF attack at the background of ACS were like those of patients with other types of AF. This group of patients was characterized by more severe course of the disease, but this produced no impact on inhospital mortality and rate of complications, as well as on mortality for 12 months after hospital discharge.

Conclusion. The results of this analysis are important for understanding distinctive characteristics of patients with AF first developed during ACS.
Clinical Capabilities and Limitations in the Use of Modern Technologies in Echocardiography
Authors: Vasyuk Yu. A. , Nesvetov V. V. , Yushuk E. N. , Scherbak M. M.
Published: July 2019

Transthoracic echocardiography is the most frequently used method for detection of impaired contractility of the left ventricle. In most cases, assessment of contractility is carried out visually “by eye”, what increases its subjectivity, is operator-dependent in nature and requires a high level of clinical training and experience of the researcher. Currently in the arsenal of a specialist in echocardiography for quantification of left ventricular contractility sometimes is used tissue Doppler echocardiography, however, this method requires special settings of the image (high frame rate, the allocation of zones of interest), depends on the scanning angle and on operator qualification, has high intra – and inter-operator variability, and significantly increases the duration of the study. Therefore, this method has not received wide clinical application. In the 2000s years an innovative technique of speckle tracking emerged, which, unlike tissue Doppler echocardiography is efficient, does not burden a researcher with time costs, has a low intra – and inter- operator variability, does not depend on scan angle. In recent years, this technology is actively implemented in clinical practice for detection of subclinical impairment of the functional state of the myocardium in different diseases and syndromes: arterial hypertension, ischemic heart disease, valvular defects, and congenital heart disease, heart failure, cardiomyopathy of different etiology.
An Experience of Meldonium Use in Patients with Ventricular Arrhythmias of Ischemic Genesis
Authors: Grigoryan S. V. , Hazarapetyan L. G. , Stepanyan A. A.
Published: July 2019

Ischemic heart disease (IHD) is often accompanied by cardiac rhythm disturbances particularly ventricular arrhythmias (VA) and their appearance in both chronic and acute forms of IHD is usually regarded as dangerous signal requiring the use of antiarrhythmic drugs. An important addition to hemodynamic therapy can be considered the use of cytoprotective drugs that improve the energy potential of cardiomyocytes. The purpose of this work is to study the comparative evaluation of the Mildronate effectiveness in patients with IHD and VA.

Methods.Under dynamic observation were 147 patients with IHD and VA (Lown II–IV functional class). The diagnosis of angina pectoris was confirmed by clinical, exercise bicycle ergometry, Holter ECG monitoring, and echocardiography data. Holter ECG monitoring was used for recording VA, heart rate, episodes of ST-segment depression. The levels of total cholesterol, triglycerides, low-density lipoprotein cholesterol (LDLC), high-density lipoprotein cholesterol were determined. All patients were randomly divided into 2 groups. The first group (81 patients) received standard antianginal and antiarrhythmic therapy plus meldonium for 2 months. The second (control) group (66 patients) received standard antianginal and antiarrhythmic therapy only. Statistical analysis of the data was carried out using the statistical package SPSS 13.0.

Results.A comparative analysis of the results showed that the use of meldonium in combination with basic therapy significantly improved clinical condition and quality of life indicators, increased exercise tolerance and improved systolic and diastolic dysfunction in patients with IHD and VA. The positive effect of meldonium on LDLC levels was observed. Moreover, the combination of basic antianginal and antiarrhythmic therapy and meldonium in patients with ischemic genesis VA promoted significant reduction of ischemic episodes and decrease of VA, in particular allorhythmia.

Conclusion.Results of this study suggest that the use of meldonium in patients with IHD and VA helps to optimize myocardial energy metabolism in conditions of ischemia and reperfusion.
Clinicopathological analysis of ovarian tumors: a two year retrospective study
Authors: Chandra Kanika , Arora Neetu
Published: July 2019

Background: Ovarian tumours are a heterogeneous neoplasm with a varied clinical, morphological and histological feature. Increasing mortality rate due to ovarian cancers has been reported in recent years. Ovarian tumours in post-menopausal females have high risk of malignancy and it has a very poor outcome. The aim and objective of this study was to determine clinical and histopathological spectrum and the frequency and age distribution of various ovarian tumors.Methods: It is a retrospective observational study of patients with ovarian tumors in the department of obstetrics and gynecology, SGRRI of Medical Health & Sciences and Hospital from January 2016 to December 2017 in a total number of 86 patients. All specimens were sent to pathology department and categorised according to WHO  hispathological classification.Results: Out of 86 cases examined, 64 cases were benign (74.4%), 3 cases were borderline (3.4%) and 19 cases were malignant (22.2%). Majority of the ovarian tumors (73.4%) were seen in the age group of 20 to 50 years. Most commonly encountered benign ovarian tumour was serous cystadenoma (58.1%). Surface epithelial tumors were the commonest tumors (64%) followed by germ cell tumors (29%).Conclusions: A variety of benign and malignant tumours of ovary were reported in this study. Early diagnosis and appropriate treatment of ovarian neoplasms favour the good prognosis. Most common benign tumour encountered in this study was serous cystadenoma.
Taking Race Live: Exploring experiences of race through interdisciplinary collaboration in higher education
Authors: Sharma Sonya , Catalano Elena , Seetzen Heidi , Julia Minors Helen , Collins-Mayo Sylvia
Published: July 2019

In this article we discuss an interdisciplinary and collaborative four-year project, Taking Race Live, that explored lived experiences of race among students enrolled at an ethnically diverse university in England. Utilizing qualitative methods to evaluate the project each year, we
draw on students' voices to address their experiences of race, partnering with interdisciplinary peers and learning about each other. Framing the discussion are the concepts of 'liveness' and 'public sociology' proposed by sociologists to bring sociological knowledge alive. Attention is given
to how this was done through engaging with the arts and embodied practices found within drama, dance and music.
Perspectives of students - Future natural sciences teachers regarded teacher’s role as educator
Authors: Mitevski Orce , Petrusheva Mitevska , Popeska Katerina Biljana
Published: July 2019

One of the important segments in the initial education of the teachers is creating positive attitudes of students for the importance of teachers’ role as educator. The aim of this research is to determine the attitudes of students – future teachers about the role of the teacher as an educator and to determine the differences in student’s attitudes regarded their sex. The study was conducted on a sample of 94 examiners, students at Teaching Faculties in Republic of Macedonia preparing for future teachers in natural sciences. Obtained results were analyzed using quantitative and qualitative analyses. Differences in student’s attitudes regarded the sex were determined using Pearson chi - square test. It could be concluded that students-future teachers in natural sciences have developed positive attitudes toward teacher’s role as educator, establishing teacher’s personal characteristics, its authority, and reputation and building quality relations with pupils as one of the important aspect. Yet it’s notable that for most of the examiners, teacher’s role as transmitter of knowledge is defined as more important and priority. These findings suggest on need for greater emphasis of the teacher as a factor in creating student’s personality through educational activities and realization of teacher’s role as educator. Keywords: Competences, pedagogical work, educator, students.
Message from editor
Authors: Ozcan Deniz
Published: July 2019

Dear Readers,It is the great honor for us to publish 7th Volume, 4th Issue of Contemporary Educational Researches Journal.Contemporary Educational Researches Journal (CERJ) welcomes original empirical investigations and comprehensive literature review articles focusing on educational issues. The journal is an international peer-refereed journal that promotes the researches in the field of contemporary teaching and learning approaches and theories. The scope of the journal includes, but is not limited to; the following major topics as they relate to: Active Learning, Administration of Education, Adult Education, Affective Learning, Classroom Assessment, Classroom Management, Classroom Teacher Education, Collaborative Learning, College and Higher Education, College and Higher Education, Learning Assessment and Evaluation, Learning Psychology, Lifelong Learning Strategies, Learning Skills, Vocational Education, Measurement and Evaluation in Education, New Learning Environments, Portfolio Assessment, Professional Development and School Administration.A total number of seventeen (17) manuscripts were submitted for this issue and each paper has been subjected to double-blind peer review process by the reviewers specialized in the related field. At the end of the review process, a total number of five (5) high quality research papers were selected and accepted for publication. Aim of this issue is to give the researchers an opportunity to share the results of their academic studies. There are different research topics discussed in the articles. For example, Azis Pollozhani and Mentor Hamiti presented a case study of Macedonia and discussed social learning as a Europeanisation tool. In another study, Brikena Xhaferi examined the impact of quality teaching on student achievement. In addition, Emine Zendelli mentioned about the right to education as a fundamental human right and tried to respond to questions on the observance of this right and whether it has been limited. Mohamad Behroozi carried out a study in order to evaluate the quality of professorsâ€™ teaching process based on studentsâ€™ view and professors of Persian Gulf University. Finally, Anna Vintere discussed implementation of the education for sustainable development strategy in mathematics education through stakeholder cooperation.The topics of the next issue will be different. You can make sure that we will be trying to serve you with our journal with a rich knowledge in which different kinds of topics are discussed in 2017 Volume.I would like to present many thanks to all the contributors who helped to publish this issue.Best regards,Assoc. Prof. Dr. Deniz OzcanEditor â€“ in Chief
Learning environment in the undergraduate chemistry laboratory courses in Beirut
Authors: Arnous Hanan , Ayoubi Zalpha
Published: July 2019

The undergraduate chemistry laboratory is an ideal place for meaningful learning to occur, and the laboratory work is considered as an integral part of most chemistry courses; however, a significant proportion of laboratory experiments remain highly prescriptive and fail to challenge undergraduate students. This study investigated the chemistry laboratory environment among 170 undergraduate students at a private university in Beirut, Lebanon. Data were collected using the Chemistry Laboratory Environment Inventory with its both versions: Actual Chemistry Laboratory Environment Inventory and Preferred Chemistry Laboratory Environment Inventory. The findings of this study showed that the students prefer a chemistry learning environment with greater levels of integration and material environment, but less level of open-endedness. Suggestions for improving chemistry laboratory learning environments are provided.

Keywords: Chemistry, laboratory, undergraduate courses, learning environment.
De la crítica a la reforma. Pensamiento político, económico, y visión de reino en las denuncias indianas de corrupción (s. XVII)
Authors: De Orellana Sánchez Juan Carlos
Published: July 2019

A partir del estudio de denuncias extrajudiciales formuladas desde Lima, Puebla, Loja y Potosí contra los excesos de los virreyes, sus criados, y otras autoridades; y de tratados jurídico-políticos, este artículo estudia la redefinición de la idea de corrupción en los reinos de indias, y contribuye al entendimiento del significado y características de la corrupción en el mundo hispánico del siglo XVII. Al hacerlo, revela que los individuos e instituciones de ciudades indianas fueron clave en la expansión y refinamiento del concepto “corrupción” lo que, a su vez, llevó a un cambio en la práctica y cultura políticas a nivel local-americano y de la corona. Esto se materializó en el cambio de la legislación indiana para respaldar a los grupos locales, sancionar a quien sirvió mal, y regular las potestades y desempeño de los principales representantes de la corona en Indias. Tan importante como eso, el discurso de corrupción generado en América incluyó la reflexión de cómo debía funcionar económicamente un reino indiano y a proponer reformas para controlarlo.
Resistencia política en la oficina salitrera de Chacabuco (1973–1975), región de Antofagasta, Chile
Authors: Tesche Roa Paula , González Javier
Published: July 2019

Este artículo se ocupa de la resistencia política, a propósito de los campos de concentración implementados en la dictadura chilena cívico militar (1973 – 1990). Al respecto, las nociones de resistencia política y de campos de concentración, son precisadas desde una perspectiva interdisciplinaria atendiendo a las complejidades y debates que comprenden tanto el contexto histórico político como el marco espacial en que se producen y que corresponde, en este caso, a la oficina salitrera de Chacabuco (1924 – 1938) actual sitio patrimonial, cuyo funcionamiento operativo fue entre noviembre de 1973 y abril de 1975.  Estos antecedentes, permiten formular como principal supuesto, que la resistencia política comprende estrategias de sobrevivencia que no solo mantienen la dignidad y los derechos humanos, sino también formas de reorganización social y ofensivas que contemplan acciones políticas, sociales y culturales. Como metodología, se consideran entrevistas semiestructuradas y revisión de material testimonial, ya publicados, de sobrevivientes. Las fuentes secundarias son de tipo académicas y de prensa. Son de especial interés, los relatos de quienes actualmente se autodenominan “Chacabucanos”, detenidos oriundos de Concepción, trasladados desde el Estadio Regional a Chacabuco, que tenían una historia de vinculación política previa, que definió estrategias de resistencia aún vigentes.
Identificação citogenética de quatro gerações de búfalos mestiços mantidos em um programa de conservação na ilha de Marajó/Brazil
Authors: Degrandi Tiago Marafiga , Marques José Ribamar Felipe , Gunski Ricardo José , Costa Maria Rosa Travassos , Figueiró Marivaldo Rodrigues , Vinadé Lucia , Marques Larissa Coelho , Garnero Analía Del Valle
Published: July 2019

Os búfalos domésticos são divididos em dois grupos: os búfalos de rio, com número diploide 2n= 50 e os búfalos de pântano, 2n= 48. O cruzamento F1 entre estes resultam em animais com 2n= 49, que são viáveis e férteis. No Brasil os búfalos do tipo Baio e da raça Carabao são mantidos em um programa de conservação genética que visa manter esses grupos separados, conservando seu patrimônio genético in situ e ex situ. O objetivo deste estudo foi avaliar citogeneticamente búfalos da raça Carabao, tipo Baio e suas crusas F1, F2, F3 e F4 mantidos em um programa de conservação genética. As metáfases foram obtidas a partir de cultura de linfócitos de 50 animais da raça Carabao, 45 do tipo Baio e 10 descendentes de uma fêmea mestiça. Os animais do tipo Baio apresentaram 2n= 50, os da raça Carabao 2n= 48. Para os descendentes foram observados 2n= 48 e 2n= 49, com variações morfológicas no primeiro par. O número diplóides 2n= 49 confirma a presença de animais cruzados no programa de conservação. Assim, a exclusão destes animais e seus descendentes é altamente recomendada dos rebanhos originais a fim de manter os genótipos separados para cada grupo genético.
Can Cowpea Intercropped Maize-Based System with Inclusion of Short Cycle Winter Crop through Soil Moisture Conservation Practices Enhance Crop, Water, Energy Productivity and Soil Health under Long Term Organic Management?
Authors: Singh Raghavendra , Babu Subhash , Avasthe R.K. , Yadav Gulab Singh , Das Anup , Mohapatra K.P. , Kumar Amit , Sharma Puscal
Published: July 2019

Organic farming has positive, impact on environment, soil health, and healthy food quality. Worldwide demand for organic foods is increasing by leaps and bounds in recent years. The present investigation was undertaken during 2014 to 2018 to evaluate the effect of cowpea (Vigna unguiculata) co-culture with maize (Zea mays L.) on productivity enhancement over prevailing maize-fallow system, and to assess the feasibility of inclusion of short duration winter crops after maize with appropriate residue management practices on productivity and soil health. The experiment comprised of six cropping systems in main plot and three soil moisture conservation (SMC) measures options in sub plot. Results indicated that the inclusion of second crop in place of fallow and cowpea co-culture with maize increased average maize grain yield by 6.2 to 23.5% as compared to that of maize-fallow (MF). Use of maize stover mulch (MSM) + weed biomass mulch (WBM) increases maize grain yield by 19.1 and 6.5% over those of MSM and no mulch (NM), respectively. Various soil moisture conservation (SMC) measures had significant (p=0.05) effect on crop yields and water productivity. Double cropping system had significantly (p=0.05) higher amount of soil available NPK, soil organic carbon (SOC), microbial biomass carbon (MBC) and dehydrogenase activity (DHA) at 0-15 cm and at 15-30 cm depth than those under MF. The SWC measures of MSM+WBM had significantly higher available N, SOC, and MBC by 5.5, 4.8 and 8.1% than those under NM, respectively. Correspondingly, soils under MSM and MSM+WBM had 2.24 and 2.99% lower bulk density (ρb) in 0-15 cm and 2.21 and 2.94% lower ρb in 15-30 cm than that of NM. The energy use efficiency (EUE) was significantly higher under MCV (7.90%) over rest of the cropping sequences. MSM+WBM and MSM recorded 25.1 and 16.6% higher net energy over NM, respectively. The net return (INR 159.99×103/ha) and B:C ratio (2.86) were significantly higher with MCV system followed by MCR cropping sequence. MSM+WBM had significantly higher net return (INR 109.44×103/h), B:C ratio (2.46) over those under MSM (INR 97.6×103/h) and NM (INR 78.61×103/h). Overall the cowpea co-culture with maize and inclusion of short cycle winter crops along with MSM+WBM in maize-based cropping systems was found productive in terms of crop and water, profitable, energy efficient and sustained the soil health.
Pertussis Immunisation in Pregnancy Safety (PIPS) Study: A Retrospective Cohort Study of Safety Outcomes in Infants Exposed to Tdap Vaccine in Utero
Authors: Petousis-Harris Helen A. , Jiang Yannan , Yu Lennox , Watson Donna , Walls Tony , Turner Nikki , Howe Anna , Griffin Jennifer
Published: July 2019

We aimed to evaluate the safety of maternal Tdap we assessed health events by examining the difference in birth and hospital-related outcomes of infants with and without fetal exposure to Tdap. This was a retrospective cohort study using linked administrative datasets. The study population were all live-born infants in New Zealand (NZ) weighing at least 400 grams at delivery and born to women who were eligible for the government funded, national-level vaccination program in 2013. Infants were followed from birth up to one year of age. There were a total of 69,389 eligible infants in the cohort. Of these, 8,299 infants were born to 8,178 mothers exposed to Tdap (12%), primarily between 28-38 weeks gestation as per the national schedule. Among the outcomes, we found a reduced risk for moderate to late preterm birth, low birth weight, small for gestational age, large for gestational age, respiratory distress syndrome, transient tachypnea of newborn, tachycardia or bradycardia, haemolytic diseases, other neonatal jaundice, anaemia, syndrome of infant of mother with gestational diabetes, and hypoglycemia in infants born to vaccinated mothers. There was no association between maternal Tdap and stillbirth, infant Apgar score at 5 minutes after birth, microcephaly, asphyxia, sepsis or infection, or hypoxic ischemic encephalopathy. Infant exposure to Tdap during pregnancy was associated with a higher mean birthweight (not clinically significant) and higher odds for ankyloglossia and neonatal erythema toxicum diagnoses. There were insufficient observations to allow examination of the effect of Tdap on extreme preterm and very preterm birth, and infant death. Overall, we found no outcomes of concern associated with the administration of Tdap during pregnancy.
HIV-1: Tackling the Obstacles, Which Limit the Effectiveness of the CRISPR-Cas9 Gene Editing of the T Cell Co-Receptor, CCR5
Authors: Hillman Tatiana
Published: July 2019

HIV-1 is a complicated and perplexing virus. It infects T cells, reverse transcribes its RNA into DNA, utilizes its host DNA machinery to replicate its HIV-DNA, translates the HIV-DNA into proteins, assembles itself for a budding escape from the T cell, and rapidly mutates its conformation. Partially, due to its complexity, there remains no cure for HIV or AIDs. However, recently with the discovery of TALENs, the use of Zinc fingers, and most of all the application of CRISPR-Cas9 technology, has given researchers a new hope in finding alternative gene therapies and treatments for diseases. With more focus on CRISPR-Cas9, this new and novel technology uses a guiding RNA, sgRNA, to lead a Cas9 nuclease to its target for deletion or to change that DNA site. The CRISPR-Cas9 can delete point mutations and multiple DNA sites. Because CRISPR can alter DNA sequences, several scientists have conducted research into CRISPR possibly curing more diseases as cancer, diabetes, and even HIV. HIV-1 drew the focus of a researcher named Dr. Ebina in 2013 when he was the first to design and apply CRISPR-Cas9 to genes found in the binding sites of the HIV-1, inhibiting HIV-1 gene expression. Since 2013 several other researchers have blocked HIV replication and infection through the CRISPR-Cas9 targeting the receptors of T cells called the CC chemokine receptor 5 or CCR5. HIV-1 binds to the CD4 receptor of T cells that consists of co-receptors CCR5 and CXCR4. If CCR5 expression can be removed, the HIV virus can not bind to T-cells, blocking the initial attachment stage, discontinuing the infection. However, there remain obstacles and issues for the CRISPR deletion of CCR5 for treating HIV-1. The issues include: 1) finding new and safe methods of CRISPR-Cas9 delivery, 2) clearing the latent HIV reservoirs, 3) improve the sgRNA design to avoid off-target mutations or deletions, and 4) effectively analyze the viral escape of HIV from CRISPR-Cas9 modifications. Therefore, the purpose of this review is to discuss possible techniques for removing the obstacles that can lessen the potential of CRISPR to delete CCR5, repressing HIV-1 into long-term remission.
Proof-of-the-Concept of Spent Mushrooms Compost Torrefaction - Preliminary Studies of Process Kinetics and the Influence of Temperature and Duration on Calorific Value of the Biochar
Authors: Syguła Ewa , Koziel Jacek , Bialowiec Andrzej
Published: July 2019

Poland is the 3rdproducer of mushrooms in the world. Mushroom production in Poland accounts for nearly 25% of the total production in the EU, and it is still growing. One type of waste generated during mushroom production is mushroom spent compost (MSC), with a 5:1 (MSC: mushrooms) production rate. We investigated valorizing the MSC to produce fuel via torrefaction (‘roasting’, a.k.a. low-temperature pyrolysis). Specifically, we developed models for the MSC torrefaction kinetics using thermogravimetric analyses (TGA) and the effects of torrefaction temperature (200~300 °C) and process duration time (20~60 min) on the resulting biochar (fuel) properties. The estimated activation energy value of MSC torrefaction was 22.3 kJ.mol-1. The highest higher heating value(HHV) = 17.9 MJ.kg-1d.m. was found for 280 °C (60 min torrefaction time). The temperature of torrefaction significantly (p<0.05) increased the HHVfor constant process duration. The torrefaction duration time significantly (p<0.05) increased the HHVfor 220 °C and decreased HHVfor 300 °C. The highest mass yield 98.5% was found for 220 °C (60 min), while the highest energy yield was found for 280 °C (60 min). In addition, estimations of the value (€132.3·Mg-1d.m. or 27.7 €·Mg-1w.m) and quantity of resulting biochar (from torrefied MSC with 65.3% moisture content) were made based on the 280°C (60 min) torrefaction variant, assuming the price of commercially available coal fuel. We have shown a concept for an alternative utilization of abundant biowaste (MSC). The initial economic evaluation showed that MSC torrefaction might be profitable. This research provides a basis for alternative use of an abundant biowaste and can help charting improved, sustainable mushroom production.
A Study on OpenFOAM's Overset Mesh Support Using Flow Past NACA 0018 Airfoil
Authors: Laws Praveen , Saini Jaskaran Singh , Kumar Ajit
Published: July 2019

The open source CFD code OpenFOAM has emerged as one of the most popular alternative to commercial CFD solvers. The recent version of OpenFOAM supports overlapping grids, so called Overset mesh. In this type of mesh, one or more sub-collection of control volumes (or cells) are allowed to overlap with other set of cells. This allows for great flexibility in modelling Fluid Structure Interaction (FSI) problems. Fluid mesh can be standard structured mesh of a rectangular/cuboidal/or cylindrical domain. The structure mesh can be generated separately by creating multiple layers around a given body. The overset mesh functionality allows for overlapping or immersing this structured mesh inside the fluid mesh and a relevant FSI or moving dynamics problems can be solved. The idea of overset mesh has been around since eighties but its support in OpenFOAM is very recent. Most CFD codes which support overset mesh have either been in-house or commercial CFD codes. OpenFOAM's support for overset is the first major open source code resource available for CFD problems. The aim of this research is to solve a classical benchmark airfoil problem using OpenFOAM overset mesh and compare the numerical results with experimental result. We report here flow simulations results around NACA 0018. The result obtained from overset mesh compares convincingly well with experimental results. Computations have been carried out for Reynolds numbers in the range of 105 with angle of attack ranging from α= 5 degree to α= 30 degree with an interval of 5 degree. Turbulence is incorporated using k - ε turbulence model. This study helps developing confidence in using OpenFOAM overset support for more complicated flows and moving dynamics. This report is complemented with a brief description of finite volume discretization using overset mesh.
An Analytic Exact form of Heaviside Function
Authors: Venetis John
Published: July 2019

In this paper, the author obtains an analytic exact form of Heaviside function, which is also known as Unit Step function and constitutes a fundamental concept of the Operational Calculus.In particulat, this function is explicitly expressed in a very simple manner by the aid of purely algebraic representations. The novelty of this work is that the proposed explicit formula is not performed in terms of non – elementary special functions, e.g. Dirac delta function or Error function and also is neither the limit of a function, nor the limit of a sequence of functions with point wise or uniform convergence. Hence, it may be much more appropriate and useful in the computational procedures which are inserted into Operational Calculus techniques and other engineering practices.
Docker4Circ: A Framework for a Reproducible Characterization of CircRNAs from RNA-Seq Data
Authors: Ferrero Giulio , Licheri Nicola , Coscujuela Tarrero Lucia , De Intinis Carlo , Miano Valentina , Calogero Raffaele Adolfo , Cordero Francesca , De Bortoli Michele , Beccuti Marco
Published: July 2019

Recently the increased cost-effectiveness of high-throughput technologies has made available a large number of RNA sequencing datasets to identify circular RNAs (circRNAs). However, despite many computational tools were developed to predict circRNAs, a limited number of workflows exists to predict and to characterize circRNAs. Moreover, to the best of our knowledge, these available workflows do not ensure computational reproducibility and require advanced bash scripting skills to be correctly installed and used. To cope with these critical aspects we present Docker4Circ, a new computational framework designed for a comprehensive analysis of circRNAs composed of: circRNAs prediction, classification and annotation using public databases, the back-splicing sequence reconstruction; the internal alternative splicing of circularizing exons; the alignment-free circRNAs quantification from RNA-Seq reads, and, finally, their differential expression analysis. Docker4Circ was specifically designed for making easier and more accessible circRNAs analysis thanks to the following features: (i) its R interface; (ii) the encapsulation of its computational tasks into a docker image; (iii) an available user-friendly Java GUI Interface. Furthermore, Docker4Circ ensures a reproducible analysis because all its tasks were embedded into a docker image following the guidelines provided by Reproducible Bioinformatics Project (RBP, http://reproducible-bioinformatics.org/). The effectiveness of Docker4Circ was demonstrated on a real case study whose goal is to characterize the circRNAs predicted in colorectal cancer cell lines and quantified in public RNA-Seq experiments performed on primary tumor tissues. In conclusion, we propose Docker4Circ as a framework for reproducible and comprehensive analyses of circRNAs to efficiently exploit their biological role.
CHARACTERISTICS OF PHYSICAL PROPERTIES OF WOOD POWDER COMPOSITES AND BAGASSEAS CONSTRUCTION MATERIALS OF SHIP
Authors: Yulika Sari Ersti , Nasution Polaris , Ramdhan1 Fajri
Published: July 2019

Parameters for measuring the physical properties on this research are divided into three elements, including measurement of weight, water absorption, and density. This research was conducted from January to March 2018 to determine the physical properties of wood powder composites and bagasse. The manufacturing and testing process refers to the ASTM and JIS standards. Weight and density testing refer to the ASTM D 792 standard while the water absorption test refers to the JIS A5908 standard. The results showed that the density of wood powder was 0.4175 gr / cm3, and the bagasse was 0.3125 gr / cm3. Then, fiber absorption in units of volume to water and resin were 16.88% and 13.75% respectively. The results showed that the largest water absorption was found in composite wood powder 60% and bagasse 40%, which was 13.47%, and for the highest density values found in wood powder composites as much as 80% or 1,078.29 kg / m3
KAJIAN FISIKOKIMIA DAN SENSORI SNACK BARS TEMPE BAGI PENDERITA AUTIS
Authors: Atmaka Windi , Parnanto Nur Her Riyadi , Utami Rohula
Published: July 2019

Kegiatan penelitian ini dilakukan dengan beberapa tahap yaitu tahap pembuatan tepung tempe, tahap
pembuatan buah kering, tahap pembuatan snack bars tempe, serta tahap analisa fisikokimia dan sensori. Formula
snackbars terdiri dari 3 variasi yaitu perbandingan antara tepung tempe dan buah kering sebesar 40:60, 50:50 dan
60:40. Buah kering yang digunakan adalah mangga dan salak. Berdasarkan hasil penelitian diketahui bahwa
tingkat kekerasan tekstur snack bars semakin tinggi dengan semakin besarnya proporsi tepung tempe. Kadar air
snack bars semakin rendah dengan semakin besarnya proporsi tepung tempe kecuali snack bars dengan
campuran buah salak. Kadar abu snack bars semakin tinggi dengan semakin besarnya proporsi tepung tempe.
Kadar protein snack bars semakin besar dengan semakin besarnya proporsi tepung tempe. Kadar lemak snack
bars semakin besar dengan semakin besarnya proporsi tepung tempe. Kadar karbohidrat snack bars semakin
rendah dengan semakin besarnya proporsi tepung tempe. Kadar serat dan total fenol snack bars tidak berbeda
nyata antar variasi sampel. Aktivitas antioksidan snack bars semakin besar dengan semakin besarnya proporsi
tepung tempe. Total kalori snackbars semakin besar dengan semakin besarnya proporsi tepung tempe.
Berdasarkan parameter overall, snack bars yang mendapatkan penilaian tertinggi dari panelis adalah snack bars
dengan campuran mangga 40:60 dan salak 60:40.
Dynamic Analysis of sRNA Regulated Quorum Sensing Network
Authors: Mei Qicheng , Liu Feng , She Jinhua , Sun Fenglan ,   School of Automation, China University of Geosciences No.388 Lumo Road, Hongshan District, Wuhan 430074, China,   Hubei key Laboratory of Advanced Control and Intelligent Automation for Complex Systems No.388 Lumo Road, Hongshan District, Wuhan 430074, China,   Key Lab of Intelligent Analysis and Decision on Complex Systems, Chongqing University of Posts and Telecommunications No.2 Chongwen Road, Nanan District, Chongqing 400065, China
Published: July 2019

The dynamics of an sRNA-regulated quorum sensing network model were investigated. The stability and the existence conditions for Hopf bifurcation were obtained. A linear feedback controller was proposed to stabilize the Hopf bifurcation of the system. Numerical simulations verified the theoretical analysis results.
Disparity Optimization Algorithm for Stereo Matching Using Improved Guided Filter
Authors: Xu Yanyan ,   Beijing Institute of Technology No.5 Zhong Guan Cun South Street, Haidian District, Beijing 100081, China, Xu Xiangyang , Yu Rui
Published: July 2019

A disparity optimization algorithm based on an improved guided filter is proposed to smooth the disparity image. A well-known problem to local stereo matching is the low matching accuracy and staircase effect in regions with weak texture and slope. Our disparity optimization method solves this problem and achieve a smooth disparity. First, the initial disparity image is obtained by a local stereo matching algorithm using segment tree. Then, the guided filter is improved by using gradient domain information. Lastly, the improved guided filter is adopted as the disparity optimization method to smooth the disparity image. Experiments conducted on the Middlebury data sets demonstrate that by using the proposed algorithm in this paper, the smoothness of the disparity map in slope regions is improved, and a higher precision of dense disparity is obtained.
Forecasting Realized Volatility in Financial Markets Based on a Time-Varying Non-Parametric Model
Authors: Gu Wentao , Liu Zhongdi , Dong Cui , He Jian , Hsieh Ming-Chuan ,   School of Statistics and Mathematics, Zhejiang Gongshang University 18 Xuezheng Street, Xiasha Education Park, Hangzhou, Zhejiang 310018, China,   Research Center for Testing and Assessment, National Academy for Educational Research No.2 Sanshu Road, Sanxia District, New Taipei City 23703, Taiwan
Published: July 2019

This paper proposes a new non-parametric adaptive combination model for the prediction of realized volatility on the basis of applying and extending the time-varying probability density function theory. We initially construct an adaptive time-varying weight mechanism for a combination forecast. To compare the predictive power of the models, we take the SPA test, which uses bootstrap as the evaluation criterion and employs the rolling window strategy for out-of-sample forecasting. The empirical study shows that the non-parametric TVF model forecasts more accurately than the HAR-RV model. In addition, the average combination forecast model does not have a significant advantage over any single model while our adaptive combination model does.
The Impact of FDI on Entrepreneurship in European Countries: Mechanism and Strength
Authors: He Qiuqin , Tien-Liu Tsung-Kuo ,   Institute of Quantitative and Technical Economics, Chinese Academy of Social Sciences Room 1420, Technology Building, 5 Jianguomennei Street, Beijing 100732, China,   Office of Physical Education, Fu Jen Catholic University 8F.-2, No.127 Dazhong South Street, West District, Taichung City 40347, Taiwan
Published: July 2019

The role of foreign direct investment (FDI) in promoting entrepreneurship has attracted increasing attention from academics and policymakers. However, empirical research has failed to consider model uncertainty, leading to contradictory results. This study designs a new semi-parametric path approach to identify the mechanism and strength of FDIs’ impact on entrepreneurial activities through three levels of difference: the general, time, and country. Our results indicate that a conflicting relationship may occur between FDIs and entrepreneurial activity because the opposing influences at these three levels negate them. Nevertheless, our detailed results are important for guiding business organizations not only among the European Union, but also in specific European countries.
Explaining Disparities in AH Stock Premium Returns with Chinese Economic Policy Uncertainty: Evidence Based on a Non-Parametric Analysis
Authors: Rahman Mohib Ur , Xu Bing , Xiao Yuan , Lai Wen-Tsung ,   Research Institute of Quantitative Economics, Zhejiang Gongshang University 18 Xuezheng Road, Xiasha University Town, Hangzhou, Zhejiang 310018, China,   Yu Da University of Science and Technology No.168, Hsueh-fu Road, Tanwen Village, Chaochiao Township, Miaoli County 361, Taiwan
Published: July 2019

This paper empirically investigates the AH share premium puzzle considering the impact of economic policy uncertainty (EPU) in China, using Hang Seng AH premium (HSAHP) index data from March 2011 to June 2018. Specifically, the index of Baker, Bloom, and Davis is used as a proxy for EPU in China. The data has been divided into two periods: 0 and 1. Period 0 includes data before the launch of the stock connect program and spans from March 2011 to October 2014, while period 1 represents data from after the launch of stock connect program and spans from November 2014 to June 2018. To more robustly test the change in AH premiums after the “connect” is launched; we evaluate the impact of Chinese EPU using non-parametric kernel density estimation. The empirical results show that parameter uncertainty explains variations in price disparity and can significantly reduce the returns of the AH share premium index.
Influencing Mechanism of Patent Alliance on Technical Innovation from Network Effects Perspective
Authors: Hu Jing , Zhang Yueyi , Wang Yilin , Chiu Yi-Wen ,   College of Economics and Management, China Jiliang University No.258 Xueyuan Street, Xiasha Higher Education District, Hangzhou, Zhejiang 310018, China,   Key Laboratory of Quality Infrastructure Efficacy Research, General Administration of Quality Supervision,
Inspection and Quarantine of the People’s Republic of China (AQSIQ) No.7 Jingshun Road, Chaoyang District, Beijing 100028, China,   Zhongchao Ink Co. Ltd. No.258 Xiuyan Road, Nanhui District, Shanghai 201315, China,   Office of Physical Education, Fu Jen Catholic University No.510 Zhongzheng Road, Xinzhuang District, New Taipei 24205, Taiwan
Published: July 2019

As an important tool to promote the technical standards for enterprises, a patent alliance can reduce transaction costs and lawsuit disputes as well as accelerate the promotion and application of proprietary technologies. Moreover, it can enlarge the installed base and influence consumers’ expectations by exploiting the network effects of technical standards. As a result, it can be one of the most effective paths to resolve the problem of patent thicket and promote innovation. Based on several theories with respect to the network effects, this study analyzed the connotation and composition of network effects for technical standards and constructed a concept model that can influence innovations using a patent alliance. A questionnaire investigation was conducted, and an analysis was performed using the structural equation to examine the factors affecting the innovation of patent tools as well as their acting paths. The main research conclusions of this study are as follows: (1) patent alliance is a double-edged sword for technical innovation. The factors related to the patent alliance and network effect, such as the installation-foundation effect, consumer expectation, and positive feedback effect, promote innovation. However, the lock-in effect in the network effect hinders the innovation. (2) Identification of intellectual property and partners is the key factor that influences patent alliance innovation. (3) Standardization strategies and the government play the least role among all innovation factors influencing patent alliance.
Object-Oriented 3D Semantic Mapping Based on Instance Segmentation
Authors: Chi Jinxin ,   School of Control Science and Engineering, Shandong University No.17923 Jingshi Road, Lixia District, Jinan, Shandong 250061, China, Wu Hao , Tian Guohui
Published: July 2019

Service robots gain both geometric and semantic information about the environment with the help of semantic mapping, providing more intelligent services. However, a majority of studies for semantic mapping thus far require priori knowledge 3D object models or maps with a few object categories that neglect separate individual objects. In view of these problems, an object-oriented 3D semantic mapping method is proposed by combining state-of-the-art deep-learning-based instance segmentation and a visual simultaneous localization and mapping (SLAM) algorithm, which helps robots not only gain navigation-oriented geometric information about the surrounding environment, but also obtain individually-oriented attribute and location information about the objects. Meanwhile, an object recognition and target association algorithm applied to continuous image frames is proposed by combining visual SLAM, which uses visual consistency between image frames to promote the result of object matching and recognition over continuous image frames, and improve the object recognition accuracy. Finally, a 3D semantic mapping system is implemented based on Mask R-CNN and ORB-SLAM2 frameworks. A simulation experiment is carried out on the ICL-NUIM dataset and the experimental results show that the system can generally recognize all the types of objects in the scene and generate fine point cloud models of these objects, which verifies the effectiveness of our algorithm.
Index-Based Notation for Random Variable and Probability Space
Authors: Shibata Hiroki ,   Graduate School of System Design, Tokyo Metropolitan University 6-6 Asahigaoka, Hino, Tokyo 191-0065, Japan, Takama Yasufumi
Published: July 2019

In a conventional notation used in many studies, a probability space and state space of random variables is identified by its symbol. However, such a notation makes a formula ambiguous in a large equation. This letter proposes to use an index set to identify the probability space and state space of random variables. It is shown that the proposed notation can increase the generality of formulas without ambiguity.
Ancient Chinese Sentence Segmentation Based on Bidirectional LSTM+CRF Model
Authors: Wang Hongbin , Wei Haibing , Guo Jianyi , Cheng Liang ,   Faculty of Information Engineering and Automation, Kunming University of Science and Technology No.727 Jingming South Road, Chenggong New Area, Kunming, Yunnan 650504, China,   City College, Kunming University of Science and Technology No.50 East Ring Road, Kunming, Yunnan 650051, China
Published: July 2019

This study proposes a novel method for the segmentation of Archaic Chinese sentences based on a bidirectional long short-term memory (LSTM) + conditional random field (CRF) model. The method added a layer of linear statistical model to the traditional bidirectional LSTM neural network; it can be used for sequence annotation from the sentence level. In addition, this model introduced the stochastic gradient descent (SGD) to prevent excessive fitting, and the viterbi algorithm was used to calculate the optimal sequence of the sentences. In the experiment, this study tests the performance of the proposed method using the History of the Han Dynasty, the History of the later Han Dynasty, Three Kingdoms, and the Book of Jin, amongst others. The results show that the precision value, recall value, and F1 value are 0.77, 0.75, and 0.76, respectively, in the open test, and 0.90, 0.88, and 0.76, respectively, in the closed test.
Bifurcation Analysis and Impulsive Control of Genetic Regulatory Networks with Multi Delays
Authors: Liu Feng , Ren Jie , Dong Ting , Zheng Shiqi ,   School of Automation, China University of Geosciences No. 388 Lumo Road, Hongshan District, Wuhan, Hubei 430074, China,   Hubei key Laboratory of Advanced Control and Intelligent Automation for Complex Systems Wuhan, Hubei 430074, China
Published: July 2019

In this study, the stability and Hopf bifurcation of a genetic regulatory network with delays are addressed. Some bifurcations may cause network oscillation and induce instability. An impulsive control method is proposed to control the bifurcations. A numerical simulation was performed to demonstrate the effectiveness of the theoretical results.