bluuebunny/crossref_metadata_2025 huggingface dataset:
Attitudes of Healthcare Students Towards Interprofessional Education
Authors: Aziz Ayesha , Hassan Sawaiz
Published: February 2025

Objective

Interprofessional education (IPE) is increasingly recognized as crucial for effective healthcare
delivery. This study aimed to assess the perceptions of medical and nursing students in Pakistan using the Interprofessional Attitude Scale (IPAS).

Methods

A cross-sectional survey was conducted across various medical and nursing institutions in Pakistan. A
total of 465 students (65% medical, 35% nursing) completed the 27-item IPAS questionnaire, which was
administered online. Demographic data and previous healthcare experience were also collected. The tool was validated by 5 experts and piloted on 20 students before the study. Differences in IPAS scores based on program type (medical vs. nursing), gender, and training phase (pre-clinical vs. clinical) were analyzed using two-way ANOVA and independent samples t-tests. A p-value of less than 0.05 was considered significant.

Results

Nursing students scored significantly higher on the “Patient-Centeredness” subscale, while medical
students scored higher on the “Roles and Responsibilities” subscale. Female students, especially in the nursing cohort, exhibited more positive attitudes toward IPE (p = 0.009). Significantly higher scores were noted in pre-clinical students compared to those in clinical years (p = 0.013), suggesting positively influenced attitudes because of early exposure.

Conclusion

Healthcare students in Pakistan generally exhibit positive attitudes towards interprofessional
education (IPE). Significant variations were observed based on the type of academic program, gender, and level of training. Integrating IPE early in healthcare education programs can enhance collaborative abilities and prepare students for multidisciplinary cooperation. Future research should explore the long-term impacts of IPE and address barriers to its effective implementation.
Prevalence of Needle Stick Injury and Associated Determinants among Healthcare Employees of Tertiary Care Hospital, Bangladesh
Authors: Karim Farzana , Rahman Md Mahfuzur
Published: February 2025

Objective

Needle stick injuries (NSIs) are a recurrent issue among healthcare employees. The study aims to evaluate the frequency of needle stick injuries and identify predisposing components at a tertiary care facility in Dhaka.

Methods

This descriptive cross-sectional study was organized at six medical and dental hospitals in Dhaka,
Bangladesh from January 2023 to August 2023. The study sample consisted of 240 doctors, dentists, and paramedical staff working at the hospital. The data was collected via a structured questionnaire with nine close ended questions for the study subjects. The analysis of data was done using SPSS 23.

Results

The overall prevalence of NSIs was 60%. The main reason for incurring the injury was drawing blood
which accounts for 54% of the total injuries, the second was while performing surgery (27%) and breaking vials (12%). The predominance of the injuries happened during the morning shift (81%). A large majority, i.e., 60%, did not report their injury, and 74% of the study population reported that the vaccination for Hepatitis B was taken prophylactically. A large majority managed a needle stick injury by wound toilet (30.5%), and the same percentage of the study population ignored it.

Conclusion

This study observed that healthcare providers had a high prevalence of needle stick injuries. Hospital
administration must devise a way to increase the availability of safety equipment, reduce workload, and provide better training to reduce the risk of injury. Moreover, reporting must be made mandatory for all those who incur this kind of injury in the future and immunization must be made available.
Perceptions and Educational Needs of Bangladeshi Medical and Dental Students Regarding Artificial Intelligence in Healthcare
Authors: Chowdhury Farhana , Rehana Zinat
Published: February 2025

Objective

The increasing prevalence of artificial intelligence (AI) technologies in the field of healthcare brings
forth diverse applications. This study explores the perceptions of undergraduate medical and dental students regarding AI, their current educational opportunities related to AI, and their preferences for the delivery medium of AI curriculum in Bangladeshi medical and dental students.

Methods
A survey consisting of 32 questions was distributed to undergraduate medical and dental students from
January to June 2023 across different medical and dental schools in Bangladesh. Questions were scored on a Likert scale from 1 (strongly disagree) to 5 (strongly agree), and descriptive analyses were applied to analyze data. Descriptive statistics were applied to the data.

Results
A total of 729 responses were collected from students across medical and dental schools, with a mean
respondent age of 22.54 years. The majority of respondents agreed that AI applications would be commonly used in medicine in the future (94%) and that their use would improve medical practice (84%). Additionally, 73% recognized the necessity of using and understanding AI during their careers, and 67% supported the formal integration of AI education into medical curricula. However, 85% reported a lack of conventional AI-related educational opportunities, and 74% perceived current learning opportunities as inadequate.

Conclusion
The study highlights a significant gap in AI-related educational opportunities for medical and dental
students in Bangladesh, emphasizing the need to integrate AI training into conventional medical curricula to prepare future practitioners for its clinical applications.
Some relations between the largest eigenvalue and the frustration index of a signed graph
Authors: Stanić Zoran
Published: February 2025

Let \(\dot{G}\) be a signed graph with \(n\) vertices and the frustration index \(\ell\). We prove the existence of \(k~(k\geq \ell)\) edges \(e_1, e_2, \ldots, e_k\) of \(\dot{G}\) such that \[\begin{equation*}\lambda_1(\dot{G})\leq \lambda_1(\dot{G}-e_1)\leq \lambda_1(\dot{G}-e_1-e_2)\leq\cdots\leq\lambda_1\Big(\dot{G}-\sum_{i=1}^k e_i\Big),\end{equation*}\] where \(\lambda_1\) denotes the largest eigenvalue, and an inequality in above chain is strict unless the signed graph on the left hand side is disconnected with at least two components with the same largest eigenvalue. We also prove the existence of a connected balanced spanning subgraph \(\dot{H}\) such that \[\begin{equation*}\ell\geq \frac{\big(\lambda_1(\dot{H}\big)-\lambda_1(\dot{G})\big)\big(\Delta+\lambda_1(\dot{H})\big)}{2\Delta}\sqrt{\frac{n}{n-1}},\end{equation*}\] where \(\Delta\) is the maximum vertex degree in \(\dot{H}\), along with the equality precisely in the trivial case when \(\dot{G}\) is balanced. We also derive some consequences of the previous results.
Editorial Volume 1, 2022
Authors: Mallik Sudipta
Published: February 2025

Editorial American Journal of Combinatorics (Volume 1, 2022)
On the distance spectrum of certain distance biregular graphs
Authors: Abdon Miriam , Lobo Tayna , Del-Vecchio Renata
Published: February 2025

In this article we present an infinite family of bipartite distance biregular graphs having an arbitrarily large diameter and whose distance matrices have exactly four distinct eigenvalues. This result answers a question posed by F. Atik and P. Panigrahi in On the distance spectrum of distance regular graphs (Linear Algebra and its Applications, 478 (2015), pp. 256-273) about the existence of connected graphs with diameter \(d\) that are not distance regular, whose distance matrix has less than \(d + 1\) distinct eigenvalues.
Rank of signed cacti
Authors: Stanić Zoran
Published: February 2025

A signed cactus \(\dot{G}\) is a connected signed graph such that every edge belongs to at most one cycle. The rank of \(\dot{G}\) is the rank of its adjacency matrix. In this paper we prove that \[\sum_{i=1}^k n_i-2k\leq \operatorname{rank}(\dot{G})\leq \sum_{i=1}^k n_i-2t +2 s,\] where \(k\) is the number of cycles in \(\dot{G}\), \(n_1, n_2, \ldots, n_k\) are their lengths, \(t\) is the number of cycles whose rank is their order minus two, and \(s\) is the number of edges outside cycles. Signed cacti attaining the lower bound are determined.
InnoVision: An Advanced Navigation Aid for Visually Impaired Individuals Using GPS, GSM, and Sensor Technologies
Authors: Rodriguez III Bobby , Aquaitan Vincent , Verallo Christian Jun , Agpad Seroll , Abarte Lian Jashcha
Published: February 2025

Globally, an estimated 285 million people live with significant visual impairments, underscoring a critical need for effective navigation aids that promote independence and safety. Traditional navigation aids, such as white canes and guide dogs, are limited in detecting obstacles and ensuring user safety. This gap highlights the urgent need for innovative solutions that leverage technology to enhance mobility for visually impaired individuals. Consequently, this study aims to develop and evaluate a smart blind stick integrated with GPS, GSM, and sensor technologies. This blind stick was equipped with advanced sensors (i.e., ultrasonic and water level sensors) and modules specifically chosen for their potential to improve navigation and safety for visually impaired users. The research methodology employed Agile Scrum, focusing on iterative development, user-centric design, and continuous evaluation. Three evaluation techniques were used to assess the final product: sensor accuracy assessment, usability testing, and system general performance evaluation. The first assessment aims to measure the accuracy of sensors in estimating the distance between the device and obstacles of varying materials in the simulated environment. The results indicated a high level of accuracy, with an average computed error of 0.04. In the second stage, ten individuals volunteered to utilize the device in the simulated environment, followed by completing a standardized 20-item usability instrument. The outcome showed that the device exhibited a remarkably high level of usability (M=6.17, SD=0.88). The system reached an excellent performance level during the final evaluation, averaging 91.43%. These findings suggest that the proposed smart blind stick is accurate, user-friendly, and effective.
Tradisi Pembacaan Surat Yasin di Ponpes Panggung Tulungagung: Dampak Terhadap Nilai Sosial Kemasyarakatan dan Keagamaan
Authors: Islamiati Indria Nuri , Musthofa Chabib
Published: February 2025

The Holy Quran is a sacred scripture that plays a vital role in the lives of Muslims. Surah Yasin is one of the chapters that holds exceptional significance and benefits in daily life. The tradition of reciting Surah Yasin at Pondok Pesantren Panggung Tulungagung has become an integral part of the daily lives of students and the surrounding community. This study aims to explore the impact of the Surah Yasin recitation tradition on social and religious values in the Pondok Pesantren Panggung Tulungagung environment. This study employs a qualitative method with a descriptive approach. Data is collected through in-depth interviews, participatory observation, and documentation.The results of the research show that the tradition of reading Surah Yasin has a positive impact on social and religious values ​​in the Panggung Tulungagung Islamic Boarding School environment. This tradition strengthens social ties between students and the community, increases religious values, and deepens understanding of religion. Apart from that, this tradition also has a positive impact on the surrounding community, such as strengthening relationships, fostering a sense of caring, and increasing spirituality.
Remedios Varo, diseñadora y publicista
Authors: López Sánchez Carmina , Martínez-Oña María del Mar
Published: February 2025

El presente artículo analiza las obras de la pintora surrealista Remedios Varo Uranga, siendo el objeto de estudio el análisis de su trabajo como diseñadora y publicista, concretamente de los diseños realizados para la empresa Bayer. Por ello, a través de diferentes metodologías como la revisión bibliográfica, la catalogación junto con los métodos histórico e iconográfico se profundiza en el análisis de algunos de estos trabajos publicitarios. Pretendiendo con ello, visibilizar no solamente la labor artística de Remedios Varo, sino valorar su trabajo como diseñadora donde presenta características iconográficas y estéticas similares a su obra surrealista creando entonces, una publicidad con influencias surrealistas a la cual se añade un enfoque etnográfico de la vida cotidiana, características presentes en todos sus diseños realizados para la empresa Bayer.

Palabras Clave: Diseño gráfico, publicidad, Bayer, comunicación, diseñadoras, mujeres artistas, género
PENGGUNAAN POTRET ORANG LAIN SEBAGAI MEDIA PROMOSI (TINJAUAN EKONOMI SYARIAH dan UNDANG-UNDANG No 28 Tahun 2014)
Authors: Setyanoor Erwan
Published: February 2025

This study investigates the view of Islamic law and law number 28 of 2014 concering regulations for using other people’s pictures to be used as promotional media and how it should be so that other people’s portraits can be used as promotional media. This research is a litertature reveiw, it shows that it violates several things in islamic business ethics, the commercial use of the people’s portraits violates things such as dishonesty, lack of transparency because they have used other people’s portraits without permission. Indonesia has regulations in the form of law to prohibit this, namely law number 28 of 2014 in the first point violates article 9 number 3 which. If concluded as follows “any person without permission of the creator is not allowed to use the creation for profit”, article 12 everyone is prohibited from using other people’s portraits for commercial use without permission from the person being photographed or their heirs. Based on some of the previous things, the outhors draw the conclusion that there is harmonization between law in Indonesia and the Islamic economy, namely providing protection for one’s rights.
Konsep Akad ' Seadanya ' dalam Sistem Perdagangan Masyarakat Banjar Kalimantan Selatan
Authors: Rizali Muhammad , Zahra Pati Matu , Badrian  , Syarqawie Fithriana , Hafidzi Anwar , Hisanah Alpasa Khairatun
Published: February 2025

This journal examines the customary practices of the Banjar community in conducting "sighat akad" (contractual declaration) during transactions, which involve not only using the phrase "sell" or stating the price of the item as "I sell this shirt for fifty thousand,"but also adding the phrase "sell as is". The purpose of this research is to understand the perspective of the Shafi'i school of thought regarding the legal status of the contract of sale using the phrase "sell as is" in the Banjar community's practices. The research methodology employed in this study is field research with descriptive analysis, where data is collected through interviews and literary sources regarding the contractual agreements of buying and selling, which are then compared with the theories from the Shafi'i perspective. Based on the findings of this research, it can be concluded that according to the Shafi'i school of thought, the contract of sale using the phrase "sell as is" is permissible due to the mutual agreement between the seller and the buyer.  This perspective aligns with the main objectives of a contract, which include the presence of mutual agreement, clarity of the object and terms, rightful ownership, and immediate payment and delivery.
DINAMIKA DIGITALISASI PERBANKAN
Authors: Setyanoor Erwan
Published: February 2025

Human beings are social beings who fulfil needs of life and need others, and also need technology to support them. Technology in this era demands an understanding of it, so, it can be used in every sector in life. This article discusses technology in the financial and banking sectors that is very beneficial and helps in the traffic of payments, that is, digitalization, which is an application based on digital. Banking financial digitalization is the application of a digital system on payment traffic services. The digitalization of the economy in general has a huge potential and allows to reach Indonesia to go digital. The result of this writing is that the positive thing of financial digitization is economic traffic that is increasingly fast and even, making Small and Medium Enterprise (SME) more expanding, can empower human resources. This can be seen from the disabled Gojek/grab partner, which is practical and very easy. Manufacturers efficiently reduce transaction costs and make the cost of printing cartel money low. In addition, the existence of digitalization, it is making some parties lose jobs by replacing them with machines, creating new jobs and making communities with low ICT skills in trouble, becoming less competitive in business, generating new types of crime like cyber-crime, it causes the closure of bank offices, creating monetary policy implications, the risks of the IT security used, a shift in public savings, and reducing the currency component in base money
LITERASI EKONOMI SYARIAH TERHADAP ADAT DAGANG PELAKU EKONOMI PASAR LOS BATU KANDANGAN
Authors: Muhammad Iqbal Sanjaya  , Nor Alia
Published: February 2025

This research is based on the diversity of ethnic groups and ethnic tribes spread throughout Indonesia, one of which is the Banjar tribe, which is an economic player in the Los Batu Kandangan market. The traditions formed are not apart from the doctrines of religious teaching that are growing in the local territory. This research aims to learn about the economic literacy of Los Batu Kandangan market economic actors and the impact of the economic literature of the Los Batu Kandangan market economic actors on the traders’ custom. This research is field research with a qualitative approach. Subjects in this study are Banjarese who became an economic actor in the Los Batu Kandangan market. The subject selection technique used in this research was purposive sampling. Data collection techniques include observations, interviews, and documentation. According to the results of the research shows that the traditions formed are a blend of local culture with the development of the literature and religious teachings of Islam existing in Hulu Sungai Selatan district and they are in wellliterate category, which has been described in some indicators of Islamic economic aspects.
Pengaruh Inflasi dan Suku Bunga Terhadap Pertumbuhan Ekonomi di Provinsi Kalimantan Selatan Tahun 2018-2022
Authors: Lisda Aisyah  , Nur Habibah  , Hushila Rizqiani Awalia  , Mukhlis Kaspul Anwar  , Muhammad Arief
Published: February 2025

Abstract
Inflation is a continual increase in the purchase price of products and services. Purpose of this research is to identify how much influence inflation and interest rates have on economic growth in South Kalimantan Province. The data used are secondary data in the form of time series data including data on inflation, interest rates, and economic growth in South Kalimantan province for the period 2018-2022. Quantitative descriptive methods were used to conduct this research. It uses Multiple Linear regression analysis methods, and data processing using Eviews 12 software. The findings of this research are that inflation has no significant effect on the economic growth of South Kalimantan Province, and also interest rates have no significant effect on the economic growth of South Kalimantan Province. Then together inflation and interest rates also have no significant effect on the economic growth of South Kalimantan Province with an R-squared value of 0.636702 or 36.3%.
Keywords : Economic Growth, Inflation, Interest Rates, BI Rate
Analisis Penerapan Prinsip Etika Bisnis Islam dalam Pengelolaan UMKM "Bebek Cobek" Bangkalan Madura
Authors: Syafaah Irbatus , Rohman Abdur
Published: February 2025

This research aims to analyze the application of Islamic business ethics principles in the management of "Bebek Cobek" UMKM in Bangkalan Madura. The principles of Islamic business ethics that are applied include Unity/Tawhid, Balance, Freedom, Responsibility and Virtue. The research method used is qualitative with a case study approach. Data was collected through in-depth interviews with owners and employees as well as direct observation in the field. The research results show that the "Bebek Cobek" stall has implemented the principles of Islamic business ethics in its operations
PENERAPAN METODE ECONOMIC ORDER QUANTITY (EOQ) DALAM MANAJEMEN PERSEDIAN IKAN ASIN TENGGIRI PADA PO. SINAR INDAH DESA PAGATAN BESAR KECAMATAN TAKISUNG
Authors: Tambrin Husni , Yulia Hafizah
Published: February 2025

This research is motivated by the use of the Economic Order Quantity (EOQ) method in controlling inventory with the aim of reducing low inventory costs. By implementing EOQ, companies can avoid stock outs which disrupt the smooth supply process of salted mackerel fish and save on storage costs and ordering costs. This study aims to evaluate stock management of salted mackerel fish in PO. Sinar Indah during 2023 using EOQ. The research method used is field research with data collection techniques through interviews and documentation. Data analysis was carried out using the EOQ method. The research results show that the inventory management approach used by PO. Sinar Indah is still simple and traditional. Their policy on the supply of salted mackerel fish has not been consistent, with ordering frequencies that are not optimal. For example, the most efficient order quantity is 37 quintals per order with a frequency of 9 times a year, in contrast to the previous approach which placed orders 43 times with a smaller quantity each time. Economically, implementing EOQ can reduce total inventory costs from IDR 26,819,600 to IDR 10,403,000. Thus, this research provides an illustration that the application of EOQ can improve the efficiency of PO stock management of salted mackerel fish. Beautiful Rays significantly.
OPTIMALISASI AKSES PELUNASAN HAJI MELALUI PRODUK CICIL EMAS BSI GOLD TO BAITULLAH
Authors: Eki Puspita Ariyanti  , Bakhri Saiful
Published: February 2025

Penelitian ini dilakukan dengan tujuan untuk menyelidiki secara rinci penggunaan cicilan emas sebagai alternatif pembiayaan bagi jamaah haji. Fokus utama penelitian ini adalah untuk mendalami prosedur dan efektivitas sistem cicilan emas dalam mengatasi berbagai tantangan yang muncul selama proses pelunasan biaya haji. Dengan mengadopsi pendekatan kualitatif dan memanfaatkan teknik pengumpulan data seperti sumber data sekunder diperoleh dari artikel, dan internet, sedangkan data primer dikumpulkan melalui observasi, dan dokumentasi. Penelitian ini bertujuan untuk memberikan pemahaman yang lebih dalam tentang bagaimana cicilan emas digunakan dalam pembayaran biaya haji di Bank Syariah Indonesia. Hasil temuan dari penelitian ini menunjukkan dengan BSI Cicil Emas Gold To Baitullah pergi ibadah haji lebih terencana dan  lebih mudah, serta keberhasilan program pelunasan haji melalui cicilan emas dalam menyediakan solusi pembayaran haji terjangkau dan terstruktur. Hal ini memperluas akses bagi masyarakat untuk melaksanakan ibadah haji. Selain itu, penelitian ini juga bertujuan untuk meningkatkan pemahaman tentang peran cicilan emas sebagai opsi pembiayaan yang inklusif bagi umat Islam yang ingin melakukan haji, serta memberikan rekomendasi untuk pengembangan lebih lanjut dalam konteks perbankan syariah dan pembiayaan haji di Indonesia. Dengan pemahaman yang lebih mendalam tentang manfaat cicilan emas sebagai opsi pembiayaan, diharapkan Bank Syariah Indonesia dapat meningkatkan pelayanan kepada nasabah, sehingga dapat memenuhi kebutuhan spiritual dan keuangan mereka terkait perjalanan haji dengan lebih efektif.
Metode Pendidikan Islam di dalam Q.S. Al-Baqarah Ayat 258-259
Authors: Zubaidah
Published: February 2025

Q.S. Al-Baqarah verses 258-259 perpetuate two stories of the past that store ibrah in them, not to mention that these two verses describe several methods of Islamic education that can be applied in the learning process. These two verses tell about the debate between Prophet Ibrahim and King Namrud, then tells the story of the story of Uzair's sleeping for 100 years. As for the formulation of the problem in this study, what are the methods of Islamic education from the perspective of Q.S. Al-Baqarah verses 258-259. This type of research is library research. The subject as well as the object is Q.S. Al-Baqarah verses 258-259 along with the methods of Islamic education contained therein. The data was collected by using library survey techniques, documentation, and processed by editing, interpreting and classifying data, then the data was analyzed using the content analysis method. From the results of the study, it was concluded that the Islamic education method contained in Q.S. Al-Baqarah verses 258-259 are (1) story/story method (2) lecture method (3) punishment (targhib) method (4) dialogical method/question and answer (5) demonstration method (6) assignment method (7) group work method.
PENGARUH MODEL INKUIRI TERBIMBING TERHADAP HASIL BELAJAR IPA
Authors: Nurul Fauziah
Published: February 2025

Abstrak: Model pembelajaran sangat penting khususnya pada proses pembelajaran yang akan mempengaruhi peningkatan kualitas hasil belajar siswa. Salah satu model pembelajaran yang digunakan yaitu model pembelajaran Inkuiri Terbimbing. Penelitian ini mengkaji tentang pengaruh model Inkuiri Terbimbing terhadap hasil belajar pada pembelajaran IPA di Madrasah Ibtidaiyah Negeri 13 Hulu Sungai Selatan. Penelitian ini menggunakan jenis penelitian kuantitatif dengan metode quasi eksperimen. Berdasarkan uji hipotesis dengan menggunakan uji t memperoleh nilai Sig. sebesar 0.048 pada hasil belajar. Berdasarkan hasil uji Independent Sample t-test diperoleh informasi bahwa seluruh tes signifikan menunjukkan angka 0.048 < 0.05 maka Ho ditolak dan Ha diterima dengan demikian dapat diputuskan bahwa terdapat pengaruh model Inkuiri Terbimbing terhadap hasil belajar. Hasil analisis korelasi diperoleh nilai r hasil belajar 0.688 dengan demikian dapat diputuskan bahwa terdapat pengaruh Inkuri Terbimbing terhadap hasil belajar siswa kuat.
Kata Kunci: Model Inkuiri Terbimbing, Hasil Belajar, IPA
KEMUNCULAN KEMAMPUAN LITERASI PERMULAAN ANAK USIA DINI
Authors: Nor Amalia Abdiah  , Noranisa
Published: February 2025

Majority of parents assumes that reading, writing, and counting as a child's literacy ability, therefore they measure the success of PAUD with the success of children being able to read or count in the early childhood. However, literacy is not limited to the ability to read, write and count, but also emergent literacy which refers to what children learn before they are able to read and write. Therefore, emergent literacy is the foundation for higher literacy skills including reading, writing and more complex language comprehension. The method used in this study is descriptive statistics, through filling out a Guttman scale containing 16 statements filled out by pre-school teachers/parents. The results obtained from this study is high score of emergent literacy due to the influence of active social interaction by children with their peers, and other adults, which proves that activeness in social interaction will further improve early childhood literacy.
Pemberdayaan Ekonomi Rumah Tangga melalui Pelatihan Pembuatan Nugget Sayuran untuk Ketahanan Ekonomi Masyarakat Berisiko Stunting
Authors: Usman Moneyzar , Darmawan Arif , Rahmalia Dian , Safitri Tina
Published: February 2025

The family's economic inability to fulfill basic food needs is one of the causes of stunting, which inhibits child growth and development. This encourages every family in the community to emphasize the importance of strengthening the household economy. Effective household economic management contributes to the fulfillment of family nutrition, in line with improved consumption patterns based on socioeconomic status. This activity is located in Way Gelam Village, Candipuro Sub-district, where the Women Farmers Group (KWT) in the village utilizes yard vegetables as the main commodity developed by the local community. This is also a strong basis for developing value-added products, one of which is vegetable nuggets. The purpose of this service is to increase household economic capacity through KWT empowerment and encourage vegetable consumption to reduce the risk of stunting due to malnutrition. The methods used include surveys, FGDs, observations, and demonstrations. The results of this service activity include partners gaining knowledge and assistance in making vegetable nuggets. A total of 100% of partners expressed satisfaction that the Service team provided services and assistance that suited their needs.
A Review of Engineered Bacterial Nanobots for Targeted Cancer Therapy
Authors: Saanvi Pratapwant  , Parimala Vudikala  , Chaitanya B
Published: February 2025

The convergence of synthetic biology and nanotechnology has given rise to bacterial nanobots as innovative therapeutic agents for cancer treatment. These bioengineered microorganisms integrate the inherent capabilities of bacteria with synthetic nanostructures to create autonomous, self-propelled systems capable of precise tumor targeting. The remarkable ability of bacteria to sense environmental cues, penetrate tumor tissues, and colonize hypoxic regions makes them ideal candidates for targeted cancer therapy. Recent advances in bacterial engineering have led to the development of sophisticated systems that can deliver therapeutic payloads, including cytotoxic agents, prodrug-converting enzymes, and immunomodulators. Various bacterial species, such as Salmonella typhimurium, Escherichia coli, and Magnetococcus marinus, have been successfully engineered through surface modification, genetic manipulation, and integration with synthetic nanostructures. These modifications enhance tumor targeting, therapeutic efficacy, and controlled payload delivery. The application of bacterial nanobots has shown promising results in preclinical studies, demonstrating improved tumor penetration, targeted drug delivery, and enhanced immune responses. However, several challenges remain, including safety concerns, immune system interactions, and regulatory considerations. Addressing these challenges through innovative engineering approaches and rigorous safety protocols will be crucial for advancing bacterial nanobots toward clinical applications.
A Review of Industrial Applications of Green Chemistry
Authors: Sai Laya Ch  , Shanmukha Siva Naga Saroja K  , Lakshmi Aswini V  , Sameera M  , Jayasree M  , Usha Rani E  , Govindarao Kamala  , Ravi Prakash Degala
Published: February 2025

Green chemistry has emerged as a transformative approach in modern chemical practices, fundamentally altering how chemical processes and products are designed, manufactured, and implemented across industries. The field emphasizes minimizing environmental impact through waste reduction, energy efficiency, and renewable resource utilization. Recent advancements in catalysis, biomimicry, and sustainable synthesis methods have revolutionized industrial chemical processes. The integration of green chemistry principles has led to significant developments in pharmaceutical manufacturing, polymer production, and nanomaterial synthesis. These innovations have resulted in reduced toxic waste generation, improved energy efficiency, and enhanced product safety. The implementation of the twelve fundamental principles of green chemistry has guided the development of environmentally conscious methodologies across various sectors, including drug development, materials science, and industrial manufacturing. Notable achievements include the development of solvent-free reactions, bio-based catalysts, and environmentally benign synthetic routes. The pharmaceutical industry has particularly benefited from green chemistry applications, resulting in cleaner drug synthesis processes and reduced environmental impact. The economic viability of green chemistry approaches, coupled with their environmental benefits, positions this field as a crucial driver of sustainable industrial development.
Phytochemical Screening and Evaluation of Thrombolytic Activity of Methanolic Extract Ixora coccinea Flowers
Authors: Rasajna G  , Daya Suniksha Devi D  , Bhanu Prashanthi G  , Anantha Lova Bhavani E  , Bhargavi V  , Lakshmi Ashwini K  , Sudheer M  , Dattatreya Krishna J
Published: February 2025

This research work involves investigation of the pharmacognostic characteristics, phytochemical composition, and thrombolytic potential of Ixora coccinea flowers. The microscopic analysis of the dried flower powder reveals distinct features including xylem vessels, lignified epidermal trichomes, sclerenchyma, oil glands, calcium oxalate crystals, and aleurone grains. Pharmacognostic screening revealed a swelling index of 0.57%, loss on drying at 5%, total ash value of 35%, and acid-soluble ash at 4.61%. Methanolic extraction of the dried flowers yielded 8.32g of extract, which showed the presence of alkaloids, terpenoids, flavonoids, glycosides, and steroids through phytochemical screening. The In vitro thrombolytic activity assessment showed concentration-dependent clot lysis effects. At 1000 μg/mL, the methanolic extract exhibited 77% clot lysis compared to 79% shown by standard streptokinase, indicating significant thrombolytic potential. The progressive increase in thrombolytic activity correlated with increasing extract concentrations (100-1000 μg/mL). These results show that Ixora coccinea flower extract possesses notable thrombolytic properties comparable to standard medication, potentially attributable to its diverse phytochemical constituents. The results support the traditional therapeutic applications of Ixora coccinea and highlight its potential as a natural thrombolytic agent.
Antimicrobial Activity and Phytochemical Evaluation of Neolamarckia cadamba Leaf Extract
Authors: Lakshmi Satvika Konatham  , Vandana Molleti  , Tarangini Elugubanti  , Sravani Thota  , Manasa Volleti  , Kalyani Arugula  , Mb Husnara Begum Md  , Govindarao Kamala
Published: February 2025

The present research work involves evaluation of the antimicrobial properties and phytochemical composition of Neolamarckia cadamba leaf extracts. Mature leaves were collected, processed, and extracted using distilled water as the solvent through maceration for seven days. The extracts were evaluated for their antimicrobial activity against five pathogenic bacteria: Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis, and Salmonella typhi using the agar cup plate diffusion method. The minimum inhibitory concentration (MIC) values ranged from 0.1 to 5 mg/mL, with significant inhibition zones observed at concentrations of 100 and 200 µg/mL. Phytochemical screening revealed the presence of several bioactive compounds including alkaloids (confirmed through Wagner's, Dragendorff's, and Mayer's tests), saponins (foam test), phenolic compounds (ferric chloride test), and proteins and amino acids (Million's and ninhydrin tests). The antimicrobial efficacy was compared with standard antibiotics gentamycin and tetracycline. The aqueous extract showed considerable inhibitory activity against both gram-positive and gram-negative bacteria, with maximum inhibition observed against E. coli and S. aureus. These results show that N. cadamba leaf extracts possess significant antimicrobial properties, potentially attributable to the synergistic effects of the identified phytochemical constituents
Phytochemical Analysis and In-vitro Anti-inflammatory Activity of Proboscidea louisianica Leaf Extract Using HRBC Membrane Stabilization Assay
Authors: Hemalatha Nakka  , Ahalya Tiriveedhi  , Kalyani Ande  , Sabitha Kopuri  , Hemasundararao Kandesi
Published: February 2025

This research work involves investigation of the phytochemical composition and anti-inflammatory properties of Proboscidea louisianica leaf extract. Fresh leaves were collected, authenticated, shade-dried, and subjected to Soxhlet extraction using n-hexane as the solvent. Preliminary phytochemical screening revealed the presence of steroids, saponins, tannins, flavonoids, phenolic compounds, glycosides, proteins, and amino acids, while carbohydrates were absent. The anti-inflammatory activity was evaluated using the human red blood cell (HRBC) membrane stabilization method, with diclofenac sodium as the standard reference drug. The n-hexane extract demonstrated dose-dependent membrane stabilization effects at concentrations of 100, 200, 300, and 400 µg/mL, showing 67.85%, 76.71%, 83.28%, and 91.57% protection, respectively. These results were comparable to the standard drug diclofenac sodium, which exhibited 86.79%, 89.78%, 93.79%, and 96.76% protection at similar concentrations. The significant membrane stabilization effect of the extract suggests its potential as an anti-inflammatory agent, possibly due to the presence of beta-sitosterols and other bioactive compounds
A Prospective Study of Risk Factor Analysis and Treatment Outcomes of Chemotherapy in Cancer Patients
Authors: Ravi Prakash Degala  , Govinda Rao Kamala  , Ratna Priya G  , Jyothi Manne  , Hyndavi Trylockya Nagumantri  , Veera Naga Lalitha Nakkina
Published: February 2025

Cancer treatment outcomes are significantly influenced by patient-specific risk factors and chemotherapy regimen effectiveness. A hospital-based prospective study was conducted to evaluate the relationship between various risk factors and chemotherapy treatment outcomes in 150 cancer patients. Patient data was collected using standardized assessment tools including the Barthel Index for physical functioning, Cumulative Illness Rating Scale for comorbidities, Hospital Anxiety and Depression Scale for psychological assessment, and Medical Social Support Survey Scale for social support evaluation. Treatment effectiveness was assessed using Response Evaluation Criteria in Solid Tumors (RECIST). The mean age of patients was 50.57±12.62 years, with females comprising 66.7% of the study population. Reproductive system cancers were predominant (50.66%), followed by digestive system malignancies. Physical functioning analysis revealed 62% of patients were independent in daily activities. Gastrointestinal adverse effects were most common (27.5%), followed by hematological (24.5%) and dermatological complications (21%). Progressive disease was observed in 37.3% of patients, while 35.4% showed stable disease. Significant associations were found between treatment outcomes and age (p=0.027), physical functioning (p=0.0076), comorbidities (p<0.00001), anxiety and depression (p<0.000072), and adverse reactions (p<0.00001). Social support levels did not show significant correlation with treatment outcomes (p=0.918619). The results of this study indicate that early identification and management of modifiable risk factors could improve chemotherapy outcomes and patient care quality.
Research on the Integration of Blockchain and IoT-Oriented AI in Intelligent Laboratory Mouse Management Systems: Web 3.0 Technology-Driven Applications and Practices for Laboratory Animal Management
Authors:   ,   HK Smart Mouse Lab Manager Limited, Sun Haomiao , Lv Zehui , Zhao Pengyu , Zhang Mingxiao ,   School of Pharmacy (Institute of Pharmaceutical Sciences), Shandong First Medical University (Shandong Academy of Medical Sciences), Jinan 250117, China,   Technology Department, Zhongke Shuchuang (Xiamen) Intelligent Science and Technology Research Institute (Limited Partnership), Fujian 361015, China, Ni Rongxiao , Zhang Lujie , Huang Changquan
Published: February 2025

The technical architecture establishes a multi-node data certification platform via consortium blockchain, integrates the InterPlanetary File System (IPFS) for distributed encrypted storage of experimental data, and automates ethical reviews, experimental protocol supervision, and resource allocation through smart contracts. Innovatively, the system mints NFT-based digital identity certificates with unique digital fingerprints to comprehensively document genetic profiles, experimental histories, and medical records of individual mice, ensuring verifiability and tamper-resistance of full-lifecycle data.At the governance level, a token-based economic model and decentralized autonomous organization (DAO) framework are introduced. Dynamic incentive mechanisms promote secure cross-institutional research data sharing, while on-chain voting protocols enable decentralized scientific decision-making, effectively balancing open data access with privacy protection requirements. This system establishes a trusted data infrastructure spanning "biological individuals-experimental processes-research outcomes," providing a scalable Web 3.0 paradigm for digital transformation in life sciences. It drives the evolution of laboratory animal management toward intelligent, standardized, and ethics-compliant practices.
हिंदी उपन्यासों में नारी चेतना
Authors: इंगळे ज्योती पांडूरंग
Published: February 2025

सारांश

नारी चेतना की अवधारणा एक जटिल और बहुआयामी है। इसे जागरूकता के रूप में परिभाषित किया जा सकता है कि महिलाओं के अपने अनुभव, विचार और भावनाएं हैं, साथ ही साथ इन अनुभवों को उनके लिंग द्वारा आकार दिया जाता है। नारी चेतना अक्सर साहित्य के माध्यम से व्यक्त की जाती है, और हिंदी उपन्यास कोई अपवाद नहीं हैं। हिंदी उपन्यासों में सबसे आम विषयों में से एक आत्म-अभिव्यक्ति का संघर्ष है। हिंदी उपन्यासों में महिलाएं अक्सर अपने परिवार और समाज की अपेक्षाओं से घुटन महसूस करती हैं। उनसे कम उम्र में शादी करने, बच्चे पैदा करने और अपने घरेलू कर्तव्यों पर ध्यान देने की उम्मीद की जा सकती है। नतीजतन, वे महसूस कर सकते हैं कि उनके पास अपने जीवन पर कोई आवाज या नियंत्रण नहीं है। कई हिंदी उपन्यासों में महिला नायक हैं जो अपनी आवाज खोजने और खुद को अभिव्यक्त करने के लिए संघर्ष कर रही हैं। ये महिलाएं कविता लिख सकती हैं, पेंट कर सकती हैं या बस अपने मन की बात कह सकती हैं। वे उन पारंपरिक भूमिकाओं को चुनौती दे सकते हैं जो समाज ने उन्हें सौंपी हैं, और ऐसा करने के लिए उन्हें उत्पीड़न का सामना भी करना पड़ सकता है।
La protección del medio ambiente y el estado de nuestros recursos
Authors:   AVIC, Ruiz Lizundia José Luis
Published: February 2025

El presente artículo intenta dar una visión sobre la situación actual de la protección del Medio Ambiente. Expone el matiz positivo que puede tener la aplicación de una política de nuestros recursos, resalta los déficits que hoy padecemos y apunta mecanismos de ayuda para su implantación.
Los residuos industriales: un esfuerzo tecnológico para su eliminación y tratamiento
Authors:   INASMET, Solozábal Echevarría R. , Vieitez Chamosa J.A. ,   INASMET, Múgica Iraola J.C. ,   INASMET
Published: February 2025

Se presenta un análisis de la problemática planteada en tomo a los residuos índustriales desde diversos puntos de vista. Se agrupan los residuos teniendo en cuenta los sectores que los generan y la naturaleza de los mismos. Con los datos díspon les, se cuantifican los residuos generados en Euskadi y en España, haciendo especial mención a los denominados residuos tóxicos y peligrosos (RT y P) por la carga contaminante que contienen o por la peligrosidad de los mismos. A continuación se hace un breve análisis de las técnicas clásicas de eliminación de residuos, y de su posible recuperación y valorización, destacando especialmente estas últimas por su positiva repercusión técnico-económica y medioambiental Se analizan, asimismo, algunas líneas de investigación y desarrollo (I+D) que en el ámbito de los Programas Marco y otros de la CEE se refieren a temas específicos del medio ambiente. Finalmente, se incluye un breve resumen de los puntos más significativos del Plan Nacional de Residuos Tóxicos y Peligrosos de reciente aparición y que consideramos de interés para los sectores industriales y los profesionales involucrados en estos temas.
La contaminación de origen industrial en el territorio histórico de Guipúzcoa
Authors:   Diputación Foral de Gipuzkoa, Pérez Olozaga Carlos , Izco Félix ,   Diputación Foral de Gipuzkoa
Published: February 2025

El presente trabajo tiene como objeto analizar los principales aspectos de la contaminación en la provincia de Gipuzkoa. Tras un breve repaso de la incidencia de las emisiones industriales atmosféricas en los núcleos urbanos se plantea la problemática de los residuos sólidos urbanos y la situación actual de las plantas de tratamiento existentes en el territorio. A continuación se señalan los resultados de un estudio de caracterización y clasificación de los residuos sólidos generados por la industria guipuzcoana y su distribución por Sectores Industriales y Comarcas. Asimismo se realiza una distribución similar para los vertidos industriales, indicando sus efectos sobre la calidad de los ríos de la provincia. Finalmente se abordan los Planes Generales de tratamiento y eliminación de los referidos residuos.
Los ríos de la Comunidad Autónoma del País Vasco: objetivos de calidad y planes integrales de saneamiento
Authors:   Viceconsejería de Medio Ambiente del Gobierno Vasco
Published: February 2025

Es notorio el mal estado en que se encuentran los cursos superficiales en la Comunidad Autónoma Vasca. Su recuperación depende en gran medida de una adecuada planificación hidrológica, que fije los objetivos de calidad para cada tramo de río en función de los diferentes usos, asi como de la puesta en marcha de planes de saneamiento que proporcionen la infraestructura necesaria para el tratamiento adecuado de las aguas residuales.
El Grupo Cooperativo Mondragón ante el reto de la Europa Económica de 1993
Authors:   Grupo Cooperativo Mondragón, Gárate Aizpuru José Ignacio
Published: February 2025

El Grupo Cooperativo Mondragón se enfrenta a la necesidad de reestructurar su modelo de organización y adaptar sus estrategias empresariales para responder en desarrollo a una nueva realidad económica desde las oportunidades que se derivan de la dimensión alcanzada y con la mirada puesta en el mercado europeo de 1993. Estos cambios supondrán la apertura hacia una nueva etapa que, coincidiendo con el relevo generacional de los hombres que han llevado la dirección con vocación, acierto y estilo ejemplarizante desde los puestos clave de toda la organización del Grupo, debe encontrar los términos de equilibrio entre las necesidades sentidas por las generaciones de jóvenes que se incorporan al mundo del trabajo y el espacio empresarial que se precisa para conquistar cuotas de mercado y generar puestos de trabajo estables en un entorno altamente competitivo. Todo ello sin que se conculquen los principios de democracia industrial, solidaridad y soberanía del trabajo.
Internacionalización de la empresa vasca: estrategias y políticas para los años 90
Authors:   Universidad del País Vasco, Velasco Roberto
Published: February 2025

Con el telón de fondo del proceso de globalización de la economía mundial, el autor señala que el sistema económico vasco es muy abierto al exterior pero escasamente íntemacíonalizado. Para superarlos desafíos de la creciente competencia en los mercados exterior e interior, se índíca que las empresas vascas deben considerar su intemacíonalización como un objetivo estratégico en cuatro aspectos relevantes -insumos, producción, mercados y tecnología-, modificando radicalmente el enfoque pasado y presente. El autor recomienda una estrategia de cooperación contractual exterior, apoyada inicialmente en acuerdos parciales, frente a las más rígidas operaciones de concentración. Y termina apuntando que la Administración Pública debe preparar el marco en el que la cooperación exterior pueda realizarse, describiendo algunas iniciativas e indicando direcciones para la actuación de los poderes públicos.