bluuebunny/crossref_metadata_2025 huggingface dataset:
Challenging the 'cultural hegemony' of the left in Cold War Turkey: the case of the Yeniden Millî Mücadele (National Struggle Anew) movement
Authors: Bertuccelli Fulvio
Published: December 2021

This article explores the creation of consensus around official and unofficial anti-communist activities in Turkey by focusing on the weekly periodical Yeniden Millî Mücadele /National Struggle Anew (1970-1980) as a case study. The magazine described itself as a publication
that was anti-communist, anti-capitalist, anti-zionist and respectful towards religious beliefs, and was associated with the national islamist organisation Mücadele Birliği (Union for Struggle). After a brief historical outline, the paper discusses some of the basic ideas
of the magazine, and shows that these were intricately connected with the ideological struggle against the supposed cultural hegemony of the left. It then illustrates how National Struggle Anew took advantage of myths and symbols of the Ottoman and Turkish past in order to construct an anti-communist
discourse and the image of the nation's enemies. The investigation has been conducted through a conceptual analysis of a selection of articles that appeared in the magazine, mainly in its first year of publication.
Former les enseignants à soutenir l’autonomie de leurs élèves : le rôle de l’analyse vidéo
Authors: André Amael , Hamon Samuel , Laville Matthieu , Ruelland Guillaume
Published: December 2021

Reposant sur une méthodologie mixte, cet article vise, d’une part, à examiner les effets d’un dispositif de formation basé sur l’analyse vidéo dans des groupes de pairs sur l’évolution du style motivationnel des enseignants novices (EN). D’autre part, il a pour objectif d’identifier les éléments clés de ce dispositif du point de vue des formés. Les résultats indiquent que le dispositif a un effet significatif sur l’évolution du style des EN qui soutiennent davantage l’autonomie de leurs élèves. Par ailleurs, les résultats mettent en évidence trois éléments clés du dispositif responsables des changements : l’analyse vidéo outillée, le groupe collaboratif basé sur le partage de ressources et la durée du dispositif sur une année scolaire.
Le cercle vertueux de la résilience
Authors: Many Holly
Published: December 2021

Vulgarisé en France par le neuropsychiatre Boris Cyrulnik depuis une trentaine d’années, le concept de résilience est de plus en plus répandu dans la littérature scientifique francophone. Cette étude propose de penser l’accompagnement et la résilience des publics d’élèves à besoins spécifiques à partir d’un modèle heuristique que nous intitulons le « cercle vertueux de la résilience » dans le cadre d’un projet de recherche-intervention mené entre 2015 et 2018 au sein du lycée professionnel Ettore Bugatti d’Illzach. Nous avons pu observer relever et identifier, à travers certains dispositifs de lutte contre le décrochage scolaire, vingt-cinq « vecteurs de résilience ». Nous pouvons les considérer comme des éléments constitutifs d’un environnement favorisant le développement psychosocial d’un individu et l’émergence de la résilience de celui-ci dans un contexte d’apprentissage.
Cyberviolences de genre. Définir et rendre compte du cybersexisme dans les pratiques numériques adolescentes
Authors: Couchot-Schiex Sigolène , Richard Gabrielle
Published: December 2021

La majorité des collégien·nes et lycéen·nes français·es ont une vie cyber active. Presque tou·tes possèdent un smartphone et les réseaux sociaux en sont leur usage principal. Des études récentes ont analysé les interactions négatives s’y déployant, les qualifiant de cyberviolences dès lors qu’elles investissent en tout ou en partie le web. Ces phénomènes ont un caractère hautement genré, c’est-à-dire qu’ils encouragent la conformité à des normes de genre rigides (à bien des égards sexistes, sexuelles et homophobes). L’article documentera les cyberviolences de genre rapportées par des jeunes de la région Île-de-France, dans le cadre d’une étude réalisée par l’Observatoire Universitaire International Éducation et Prévention (Université Paris-Est Créteil) et commanditée par le Centre Hubertine Auclert. À partir de données quantitatives et qualitatives colligées auprès de centaines d’élèves de collèges et de lycées, il évoquera l’existence de faits de violence cybersexiste polymorphes et ordinaires, ciblant les garçons comme les filles, dans la mesure où leurs comportements et préférences sont considérées comme atypiques sur le plan du genre. Au final, l’article retracera la genèse de l’installation du concept de cybersexisme, que les auteures proposent pour évoquer ces violences relevant du système de genre.
Les actions de « formation en situation de travail » : notes critiques sur une formule qui s’est imposée dans le champ de la formation
Authors: Lescure Emmanuel de
Published: December 2021

Alors que la loi du 5 septembre 2018 a fait de l’action de formation en situation de travail (Afest) une modalité de formation formelle éligible à des financements publics, cet article se propose de revenir sur les discours publics qui ont accompagné cette reconnaissance et les succès de la « formule ». L’Afest fait-elle l’objet de l’engouement souvent mis en scène ? Lorsque l’on examine les discours tenus dans le magazine bimensuel spécialisé sur la formation continue, Inffo Formation, on est frappé par leur caractère consensuel. L’Afest est unanimement présentée comme une innovation utile et attractive. Un tel accord invite à s’interroger sur les attraits et les enjeux de cette nouvelle disposition légale comme de l’expérimentation qui a permis de la formaliser, et, dans une perspective programmatique, à estimer si les intentions déclarées ont quelques chances de se réaliser. Les questions ainsi soulevées sont d’ordre social, économique, politique et pédagogique.
L’accompagnement de l’apprentissage en entreprise et développement de l’agentivité. Le cas des apprenti-e-s en automatisation en Suisse
Authors: Felder Alexandra , Caprani Isabelle , Duemmler Kerstin
Published: December 2021

Basé sur une recherche qualitative sur l’expérience de formation en entreprise des apprenti-e-s automaticiens en Suisse, l’objectif de cet article est d’étudier la relation entre l’accompagnement en entreprise et le développement de l’agentivité. Quatre cas d’entreprises montrent l’influence de l’accompagnement sur la forme d’agentivité développée. Les apprenti-e-s insérés dans un contexte d’accompagnement avec une relation d’apprentissage forte avec la personne formatrice, une participation expansive à l’activité et des interventions structurantes adaptées, développent l’agentivité directement centrée sur l’optimisation des apprentissages et la prise de responsabilités. Les apprenti-e-s dans un contexte d’accompagnement mal adapté ou insuffisant ont l’impression de ne pas bien apprendre leur métier. Ils et elles développent également une pensée orientée vers l’optimisation des apprentissages, mais leur action reste centrée sur l’amélioration des conditions d’apprentissage.
Une perspective décentrée sur l’apprentissage en situation de travail : les conditions d’exercice des personnes formatrices en entreprise
Authors: Lamamra Nadia , Duc Barbara
Published: December 2021

L’article s’intéresse à l’apprentissage en situation de travail à partir des conditions d’exercice des personnes formant en entreprise. Il s’agit d’interroger la faisabilité d’une formation en situation de travail dans une organisation productive. A partir d’entretiens semi-structurés menés en Suisse romande auprès de personnes chargées de la formation des apprenti-e-s, mais aussi d’observations in situ, l’article s’intéresse aux contraintes subies et à leur impact sur le quotidien de formation. Les résultats reviennent sur le prescrit de l’activité, mais également sur les différentes manifestations du réel. Ils soulignent le primat de la production dans les différents cadres organisationnels. En outre, ils font apparaître des modalités de la formation en situation de travail, qui pourraient être qualifiées de paradoxales. Enfin, la discussion interroge la tension produire/former sous l’angle de l’écart entre prescrit/réel.
Former à « prendre sa place » dans une équipe du travail social : une dimension collective des pratiques de tutorat
Authors: Trébert Dominique , Bovey Fanny , Montefusco Camille , Zogmal Marianne
Published: December 2021

Cette contribution porte sur la formation pratique dans le champ du travail social et s’intéresse à la dimension collective des processus de formation. Elle aborde comment une étudiante peut prendre sa place dans l’activité collective du travail, et comment la tutrice et les membres d’une équipe de travail s’y ajustent. Par le biais d’une analyse des interactions, nous cherchons à accéder aux traces détaillées des modalités interactionnelles mises en œuvre au sein d’une institution socioéducative. Dans les trois extraits que nous analysons, nous montrons que prendre sa place au sein d’une équipe représente un défi permanent pour l’apprenante ; mais aussi pour les professionnel·le·s expérimenté·e·s du collectif de travail. De manière générale, la réflexion proposée s’appuie sur une perspective interactionniste et vidéo-ethnographique pour accéder aux spécificités des pratiques tutorales dans le champ du travail social.
La formation professionnelle initiale duale comme levier d’engagement organisationnel : analyse d’un dispositif de formation d’apprenti-es assistant-es en soins et santé communautaire (ASSC) dans le contexte domiciliaire
Authors: Crottaz Camille , Delobbe Nathalie , Morante Sandrine Fellay
Published: December 2021

Se référant principalement aux théories de la socialisation organisationnelle, cet article s’intéresse à un dispositif de formation professionnelle initiale duale d’apprenti-es assistant-es en soins et santé communautaire (ASSC). Il explore l’influence des pratiques de formation en situation de travail sur la fidélisation des apprenti-es dans l’entreprise formatrice. Cette contribution propose une vision élargie du spectre des apprentissages, considérant à la fois les processus d’acquisition des compétences relatives au métier et la dimension socialisatrice des pratiques de formation. Les entretiens menés au sein d’une institution de soins à domicile mettent en évidence deux éléments clés de la formation en situation de travail qui affectent le processus de socialisation organisationnelle : la définition du métier et les activités confiées aux apprenti-es, d’une part, le cercle relationnel élargi auquel ils/elles ont accès, d’autre part.
Apprentissage du travail dans des situations hybrides en formation professionnelle
Authors: Métral Jean-François , Veillard Laurent , Masson Claire
Published: December 2021

Cet article illustre la manière dont le travail peut être mobilisé en formation professionnelle initiale, dans le cadre de situations de formation hybrides dans des ateliers technologiques d’école. Il mobilise le cadre conceptuel de la didactique professionnelle pour analyser des situations de formation en atelier d’élèves préparant un Brevet de Technicien Supérieur en Sciences et Technologies des Aliments dans un établissement de l’enseignement agricole français. Il décrit comment les formateurs et formatrices déploient une ingénierie en acte des contenus et des modalités d’enseignement du travail à des groupes d’élèves, ingénierie propre à favoriser la connectivité des contenus avec les situations de travail visées. Ce faisant, il donne des pistes pour penser une ingénierie didactique et pédagogique fine des dispositifs de formation en situation de travail.
Écrire collégialement en formation pour soutenir la construction d’une identité collective au sein d’un nouveau corps de professionnel·le·s
Authors: Botty Gaëtan , Biémar Sandrine
Published: December 2021

La présente contribution interroge un dispositif de formation destiné à soutenir la professionnalisation d’un nouveau corps de professionnel·le·s, les Délégué·e·s au Contrat d’Objectifs. Dans le contexte de la Fédération Wallonie-Bruxelles de Belgique (FWB), engagée dans une réforme de la gouvernance de son système éducatif, ces acteurs intermédiaires assurent un lien entre l’administration et les écoles. L’écriture réflexive réalisée individuellement et collectivement en formation constitue l’objet de l’étude menée. Son objectif est de progressivement participer à l’élaboration d’une identité professionnelle collective qui aide ce nouveau corps à agir avec cohérence et unité. La méthodologie de recherche prend appui sur des données représentationnelles recueillies auprès des D.C.O. ayant pris part à la formation. Les analyses indiquent que le sens accordé à la tâche d’écriture ainsi que ses conditions de mises en œuvre influencent le processus de transformation identitaire.
Apprentissages ducoachen situation de travail : quelle plus-value en contexte multiculturel libanais ?
Authors: Hage Mirna , Rached Patricia , Gharib Yvette
Published: December 2021

Dans le contexte libanais multiculturel, la présente recherche s’intéresse à l’étude du cas d’un coach qui a accompagné cinq chefs d’établissements scolaires sur une année académique et lequestionne sur ses apprentissages en situation de travail.Inscrite dans le paradigme socioconstructiviste, elle adopte une approche qualitative basée sur trois entretiens semi-directifs avec lecoachainsi que l’analyse de son journal de bord. Les résultats ont révéléles apports ducoachingen termes d’affordances saisies de la relation à l’autre et des ressources de l’environnement, mobilisant desstratégies d’apprentissage et développant un agir professionnel.
Le stage d’adaptation : un lieu d’apprentissage ? Analyse du parcours d’un infirmier diplômé en demande de reconnaissance
Authors: Alber Jean-Luc , Mirza Nathalie Muller , Navarro Cécile
Published: December 2021

Les recherches actuelles montrent que, si les stages sont des leviers de la socialisation professionnelle en situation de travail, l’apprentissage ne se réalise pas par simple imprégnation. Dans cet article, nous étudions l’expérience du stage d’adaptation du point de vue d’un infirmier provenant d’un pays non-membre de l’UE/AELE, candidat à l’homologation de son diplôme en Suisse. Nous examinons les apprentissages réalisés et les difficultés rencontrées pendant cette étape de la trajectoire de formation. En adoptant une approche en socio-anthropologie et en psychologie culturelle, l’analyse porte sur des entretiens menés auprès de ce candidat, qui combine une double position, de professionnel et d’apprenant. Les résultats montrent que le stage d’adaptation est un lieu traversé par des logiques contradictoires, rendant difficile la construction d’une socialisation. Ils mettent en lumière les tensions à l’œuvre entre dynamiques d’apprentissage, d’intégration et d’altérisation.
Violences en milieu scolaire au Gabon. Regards croisés autour de l’analyse de contenu des mémoires professionnels des étudiants en fin de cycle à l’ENS de Libreville
Authors: Mongaryas Romaric Franck Quentin De , Bibalou Euloge
Published: December 2021

Depuis la tenue des États généraux de l’éducation, de la recherche et la formation (2010), l’État gabonais a engagé de nombreuses réformes dans son système éducatif afin d’assurer les meilleures conditions d'enseignement et d’apprentissage. Contrairement aux attentes politiques, les résultats obtenus restent très insuffisants dans la mesure où l’échec et les violences scolaires sont malheureusement devenus des problèmes récurrents de l’École gabonaise. Face à cette réalité, et pour tenter d’y apporter des explications, depuis environ une douzaine d’années, les étudiants en fin de cycle à l’École Normale Supérieure (ENS) produisent des mémoires professionnels sur la problématique des violences en milieu scolaire au Gabon. Dès lors, que disent-ils à propos des formes, manifestations et conséquences des violences sur les apprenants et les enseignants qui en sont victimes ? Quels enseignements en tirer ? Enfin, comment ces travaux peuvent-ils être exploités sur un plan pratique par les décideurs à la fois pour comprendre et apporter des solutions à l’insécurité grandissante dans le système éducatif gabonais ? Pour mieux répondre à ces interrogations, sans être exhaustifs, nous avons réalisé une analyse de contenu de neuf (9) mémoires recensés particulièrement à l’ENS.
A case of well-differentiated hepatocellular carcinoma identified on gallium-68 prostate-specific membrane antigen positron emission tomography/computed tomography
Authors: Huang Hian , Zhen Loh Tracy , Hoe Chow Pierce
Published: December 2021

Prostate-specific membrane antigen (PSMA) is a glycosylated type-II transmembrane protein highly expressed in certain tumor cells. To the best of our knowledge, this is the first case reported of an isolated well-differentiated hepatocellular carcinoma (HCC) strongly suspected on gallium-68 (68Ga)-PSMA positron emission tomography/computed tomography (PET/CT), which was not well characterized both on magnetic resonance imaging (MRI) liver with Primovist as well as fluorine-18 (18F)-choline PET/CT. Our patient had previous prostate cancer and previously was imaged using 18F-choline PET/CT. The last scan showed an indeterminate segment VII hypodensity which was not significantly choline-avid. The lesion was initially stable on serial MRI scans but then showed growth from 1.0 to 1.5 cm. 68Ga-PSMA PET/CT was performed. The lesion was intensely tracer-avid. This was surgically excised and histology confirmed the presence of well-differentiated HCC. Well-differentiated HCC can be optimally imaged using 68Ga-PSMA PET/CT and further prospective studies are needed to look into the potential of this imaging modality.
Accuracy of quantitative positron emission tomography assessment for differentiating cerebral age-related from pathological amyloid deposition: A preliminary report from a case-series study
Authors: Lauretani Fulvio , Ruffini Livia , Ticinesi Andrea , Nouvenne Antonio , Maggio Marcello , Meschi Tiziana
Published: December 2021

Previous observational studies using old qualitative methods have not clarified the role of amyloid positron emission tomography (PET) in the assessment of dementia. Given the moderately positive predictive value, the presence of amyloid deposition does not necessarily imply the diagnosis of dementia. Conversely, the absence of amyloid PET deposition has been shown to be useful in excluding the neurodegenerative pathology, irrespective of the aging process. We describe the clinical application of new innovative software recently developed to increase the sensitivity of this technique and to discriminate pathological deposition of cerebral amyloid from the age-related changes, reporting preliminary findings from a case-series study. In three different clinical profiles, we underline the need of integrating neuropsychological assessment and findings with this new PET scan and software that provide quantitative information of the cerebral amyloid and may increase the probability of rapid and accurate assessment of Alzheimer's disease. Although this amyloid quantification is promising, these preliminary results should be confirmed in future prospective studies with adequate sample size.
Ra223 in bone metastases with osteolytic activity
Authors: Costa Renato , Cardile Davide , Murabito Alessandra , Tripoli Vincenzo , Verderame Francesco
Published: December 2021

Radium 223 dichloride (Ra223) is the only targeted alpha therapy able to extend survival in patients with bone metastases from prostate cancer. Mechanism of action and data currently available focused mainly on osteoblastic metastases from prostate cancer. In our institution, a patient with breast cancer affected by osteolytic metastases was treated with off-label use of Ra223. The evaluation of the deposit areas of Ra223 showed a perfect overlap with the regions of osteolysis previously detected by scintigraphy, indicating a possible therapeutic effect. This case report is the first document attesting Ra223 deposit in osteolytic metastases opening new opportunity of therapeutic development for this radiopharmaceutical.
To compare and determine the diagnostic accuracy of [18F]-fluorodeoxyglucose positron emission tomography scan in predicting pathological response in operated carcinoma esophagus patients after initial neoadjuvant chemoradiation and neoadjuvant chemotherapy
Authors: Sharma Neelam , Purkayastha Abhishek , Vishwanath Sundaram , Jaiswal Pradeep
Published: December 2021

The objective of this study was to determine whether [18F]-fluorodeoxyglucose-positron emission tomography (FDG-PET) scan could predict the pathological response in esoph neoadjuvant concurrent chemoradiation (NACCRT) and neoadjuvant chemotherapy (NACT). A randomized prospective study was carried out from March 2014 to October 2016; thirty patients of histopathologically proven, locally advanced, potentially operable carcinoma esophagus comprising both squamous carcinoma and adenocarcinoma were randomized into NACCRT and NACT arms equally. Both groups had pretreatment FDG-PET-computed tomography (CT) scan and repeat scan after 5–6 weeks of neoadjuvant therapy (NAT). The change in mean %Δmaximum standardized uptake value (%ΔSUVmax) was compared with tumor regression grade (TRG) in the postoperative histology. Patients with TRG 1–2 were deemed responders and 3–5 were nonresponders. Pathologic response was correlated with percentage change in [18F]-FDG uptake (%ΔSUVmax); receiver operating characteristics (ROC) analyses were done to assess sensitivity and specificity of FDG-PET to determine its diagnostic accuracy. The mean SUV in NACCRT group decreased from 15.47 ± 2.92 to 7.31 ± 4.07 (P < 0.001), while in NACT group, mean SUV decreased from 14.74 ± 3.95 to 8.60 ± 3.89 (P < 0.001). Comparison between NACCRT and NACT leads to mean SUV of 57.80 ± 22.40 and 45.92 ± 19.23, respectively (P = 0.13). In NACCRT and NACT, TRG had mean %ΔSUVmax values of 2.53 ± 1.25 and 2.93 ± 1.28 (P = 0.393). However, we found a statistically significant correlation between SUV% reduction and TRG (P = 0.002). ROC curve analysis for FDG-PET-CT suggested an area under the curve of 0.693 and sensitivity and specificity of 80% and 46.7%, respectively. NACCRT and NACT lead to a statistically significant reduction in mean %ΔSUVmax and with statistical significance correlation when compared with pathological response assessment. Hence, PET-CT can be used for differentiating responders and nonresponders to NAT.
First results and experience with PRRT in South Africa
Authors: Vorster Mariza , Modiselle M , Corbett C , Lawal I , Buscombe John , Sathekge Mike
Published: December 2021

Neuroendocrine tumors (NETs) are a diverse group of tumors that often present late due to nonspecific symptoms. These tumors frequently express somatostatin receptors (SSRs), which allows for positron emission tomography/computed tomography (PET/CT) imaging with Ga-68-DOTATATE. In eligible patients, this may then be followed by peptide receptor radionuclide therapy (PRRT). Here, we report our initial results and experience with PRRT in a developing country, as one of the first groups to provide this therapy in South Africa. Eligible patients with confirmed inoperable NETs were recruited prospectively and treated with Lu-177-DOTATATE. Baseline imaging was performed with either single-photon emission CT- or PET-based SSR analogs, whereas follow-up was performed with 68Ga-DOTATATE PET/CT 6 months post treatment completion. Interim treatment response evaluation was based on post therapy imaging of Lu-177-DOTATATE. A total of 48 patients with a mean age of 58 years were treated with PRRT, of whom 22 (46%) demonstrated stable disease, 20 (42%) demonstrated a partial response, and 6 (12%) demonstrated progressive disease. The median progression-free survival (PFS) was 20 months with an interquartile range (IQR)25%–75%of 4.5–30 months. The median freedom from progression duration was 32 months with an IQR25%–75%of 25–40 months, and the median overall survival was 10 months with an (IQR)25%–75%of 5–24 months. Our subgroup analysis demonstrated an inverse association between metabolic tumor volume with PFS, which requires further validation. In conclusion, PRRT with Lu-177-DOTATATE resulted in a median PFS of 20 months in patients with inoperable NETs in the absence of significant side effects.
The baseline pattern and age-related developmental metabolic changes in the brain of children with autism as measured on positron emission tomography/computed tomography scan
Authors: Sharma Alok , Gokulchandran Nandini , Sane Hemangi , Nivins Samson , Paranjape Amruta , Badhe Prerna
Published: December 2021

[18F] 2-fluoro-2-deoxy-D-glucose positron emission tomography-computed tomography scan was performed on 45 children with autism to study the baseline pattern and age-related developmental changes in the brain metabolism. Median standardized uptake values (SUVs) were compared with published healthy control data. Results showed that, in contrary to control data, the median SUVs in children with autism decrease linearly with increase in age. As compared to controls, autism children below 5 years showed greater metabolism and older children showed lower metabolism. In autism group, comparison of absolute SUVs within different regions of the brain revealed relatively lower metabolism in amygdala, hippocampus, parahippocampal gyrus, caudate nucleus, cerebellum, mesial temporal lobe, thalamus, superior and middle temporal pole, and higher metabolic uptake in calcarine fissure and Heschl's gyrus. These results help in understanding the baseline metabolism and developmental changes of brain among different age groups in autism.
Massive tumor thrombus in left renal vein and inferior vena cava in renal cell carcinoma on 18-fluorodeoxyglucose positron emission tomography/computerized tomography: “suspension bridge sign”
Authors: Zaman Maseeh , Fatima Nosheen , Zaman Areeba , Zaman Unaiza , Tahseen Rabia , Zaman Sidra
Published: December 2021

Tumor thrombosis is a relatively uncommon complication of renal cell carcinoma (RCC), and its diagnosis has therapeutic and prognostic implication. Computerized tomography (CT) is the primary imaging modality for staging RCC, but it has low sensitivity to differentiate between tumor thrombus and bland or benign thrombus. 18-fluorodeoxyglucose positron emission tomography/CT (PET/CT) has a limited role in diagnosis and staging of RCC, but its diagnostic accuracy is considerably high for detection of metabolically active tumor thrombus. We are presenting a case of metastatic left-sided RCC with massive hypermetabolic tumor thrombus extending from left kidney to left renal vein and inferior vena cava giving an interesting “Suspension Bridge” appearance on PET/CT images.
Can gallium-68 prostate-specific membrane antigen ligand be a potential radiotracer for renal cortical positron emission tomography imaging?
Authors: Sarikaya Ismet , Elgazzar Abdelhamid , Alfeeli Mahmoud , Sarikaya Ali
Published: December 2021

Gallium-68 prostate-specific membrane antigen (Ga-68 PSMA) ligand (HBED-CC) is a new promising positron emission tomography (PET) tracer for prostate cancer. Intense renal parenchymal uptake is a physiologic finding on Ga-68 PSMA ligand PET images. Evaluation of kidneys in low intensity demonstrates excellent distribution of this radiotracer in renal parenchyma with excellent image quality and resolution. In this article, we present the Ga-68 PSMA ligand PET renal images of four patients with prostate cancer. In two patients, there is normal distribution of radiotracer, and in other two, there are renal cysts causing parenchymal defects.
Nuclear medicine in prostate cancer: A new era for radiotracers
Authors: Cuccurullo Vincenzo , Di Stasio Giuseppe , Mansi Luigi
Published: December 2021

Natural history of prostate cancer (PCa) is extremely variable, as it ranges from indolent and slow growing tumors to highly aggressive histotypes. Genetic background and environmental factors co-operate to the genesis and clinical manifestation of the tumor and include among the others race, family, specific gene variants (i.e., BRCA1 and BRCA2 mutations), acute and chronic inflammation, infections, diet and drugs. In this scenario, remaining actual the clinical interest of bone scan (BS) in detecting skeletal metastases, an important role in diagnostic imaging may be also carried out by, positron emission tomography/computed tomography (PET/CT) and PET/magnetic resonance imaging (PET/MRI), which combine morphological information provided by CT and MRI with functional and metabolic data provided by PET acquisitions. With respect to PET radiotracers, being ancillary the usefulness of F-18 fluoro-deoxyglucose and not yet demonstrated the cost-effectiveness of F-18 Fluoride respect to BS, the main role is now played by choline derivatives, in particular by 11C-choline and 18F-fluorocholine. More recently, a greater interest for both diagnostic and therapeutic purposes has been associated with radiotracers directed to prostate-specific membrane antigen (PSMA), a transmembrane protein expressed on the cell surface, which showed high selective expression in PCa, metastatic lymph nodes and bone metastases. Several PSMA-targeted PET tracers have been developed many of which showing promising results for accurate diagnosis and staging of primary PCa and re-staging after biochemical recurrence, even in case of low prostate specific antigen values. In particular, the most widely used PSMA ligand for PET imaging is a 68Ga-labelled PSMA inhibitor, 68Ga-PSMA-HBED-CC (68Ga-PSMA-11). 99mTc-HYNIC-Glu-Urea-A for single photon emission computed tomography, and 177Lu-PSMA-617 for radioligand therapy has also been applied in humans, with interesting preliminary results related to a possible theranostic approach. A potential role of PSMA radioligands in radio-guided surgery has also been proposed.
Renal manifestation of Birt–Hogg–Dubé syndrome depicted by 18F-fludeoxyglucose positron emission tomography/computed tomography in a patient with hurtle cell thyroid malignancy
Authors: Panagiotidis Emmanouil , Seshadri Nagabhushan , Vinjamuri Sobhan
Published: December 2021

Birt–Hogg–Dubé (BHD) syndrome is an autosomal dominant genetic disorder characterized by small papular skin lesions (fibrofolliculomas) causing susceptibility to kidney cancer, renal and pulmonary cysts, spontaneous pneumothoraces, and several noncutaneous tumors. We report a case of a 67-year-old woman, with a previous history of right hemithyroidectomy for adenomatous lesion. She presented with a swelling in the right thyroid bed that on subsequent biopsy revealed features of metastatic carcinoma. 18F-fludeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) performed for the detection of primary malignancy showed increased high-grade metabolic activity in the right supraclavicular soft tissue mass extending into the superior mediastinum. Moreover, on low-dose CT, there have been bilateral renal interpolar cortical lesions with mild metabolic activity. Given the fact that the right neck mass was highly unlikely to represent renal metastases in the absence of widespread metastatic disease, surgical excision of the right neck mass was performed. The histology of the mass was in keeping with hurtle cell thyroid carcinoma. In regard to renal lesions, bilateral partial nephrectomy was performed, which was consistent with chromophobe renal cell carcinoma, raising the suspicion of BHD that was confirmed by the subsequent genetic evaluation. It is well established that 18F-FDG PET/CT study is not an optimal modality for evaluation of renal lesions. However, careful assessment of the CT features in conjunction with the associated metabolic activity of the 18F-FDG PET component increases the diagnostic accuracy of PET/CT.
Investigation of extraction method effect on yeast beta glucan production
Authors: KARSLIOĞLU Fatma , ERTUNÇ Suna , YİLMAZER HİTİT Zeynep , AKAY Bülent
Published: December 2021

Nowadays, due to the stressful, tiring and busy lives of humans, the immune system becomes weak and can get sick easily. Therefore, scientists have been doing researches about new, natural and healthy products that can strengthen their immune system and can provide to adapt life standards. One of these products is the beta glucan. It is a polysaccharide molecule that consists of D-glucose monomers bonding with beta glycosidic bonds. Beta (β) glucans have being produced from different sources (microorganisms, cereals and mushrooms) so they have different branched structures such as (1→3) (1→6), (1→3) (1→4), (1→3) (1→2). Thus, different branched beta glucans show different physicochemical properties and biological activities that designate their usage purposes. Especially yeast beta glucan has lots of biological activities. On the other hand, it is fact that the extraction method affects the molecular weight, yield, purity and other properties of beta glucans. The main purpose of this study is to compare the performances of ultrasonically assisted alkali-acidic and autolysis extraction methods to produce a high yield of beta glucan. Also, it was aimed to determine the effect of extraction method on the molecular weight of yeast beta glucan. As a result of this work, it was found that the yeast beta glucan yield for ultrasonic supported autolysis extraction (12 %) is higher than that of the ultrasonic supported alkali-acidic extraction (8 %). On the other hand, having the lower molecular weight of yeast beta glucan (87 kDa) was produced by using an ultrasonic supported autolysis extraction method.
Technological importance of asteroid mining
Authors: ÇABUK Senem , ÇABUK Nazım
Published: December 2021

With the ever-growing demands of the population and the ever-growing world of consumption and technology, the resources of the planet Earth are limited. According to Cohen (2007), some of the Earth's major resources, such as metals and minerals needed to develop the technology and food industries, may be depleted within the next 40-50 years, based on known terrestrial reserves and increased consumption. For industrial and technological development of humanity, new discoveries are needed in future realization as well as future discoveries. Asteroids are celestial bodies of scientific importance to reveal the formation, chemical composition and evolution of the Solar System. As the name implies, "Near Earth Asteroids", metal have been found to be potentially close to possible because they are sufficiently close and can be found in precious metals and minerals. The reservoirs of important substances such as water, metals and semiconductors can be found in these celestial bodies. Although the Asteroids and the Earth are composed of the same elements, the Earth's relatively stronger gravity has attracted all the heavy elements to its core over time. An asteroid rain deprived of such valuable elements results in the formation of gold, cobalt, iron, manganese, molybdenum, nickel, osmium, palladium, platinum, rhenium, radium, ruthenium and tungsten elements (from the core to the surface). Today, these metals are extracted from the Earth's crust and are required for economic and technological advancements. Therefore, the geological history of the Earth can be a very good step for the future of asteroid mining.
Determination of polycyclic aromatic hydrocarbons in algae : Giresun coastline-Eastern Black Sea Region
Authors: YÜCEL Tayyibe Beyza
Published: December 2021

In this study, in the spring of 2019, algaes of Ulva species were collected from eigh station in Giresun costline (Piraziz port, Bulancak port, Giresun port, Keşap station, Espiye-Opet stations, Tirebolu station, Görele station and Eynesil station in May. They are brought to the laboratory in polyethylene bottles. In general, the amount of seaweed samples to be tested was weighed around 15-20 g. Wet algae samples are extracted by methanol solutions with Soxhlet apparatus for 12 hours. By applying the necessary purification processes to the obtained solution, the concentrations of 16 PAH components were determined with the GC/MS device. The amount of most of the 16 PAH compounds in the Keşap site seaweed samples was the highest. The highest amount compounds are found to fluorene, phenanthrene and antresen, and it is high in Bulancak, Giresun-Liman and Keşap sites. It belongs to seaweed samples collected from Piraziz site, which has the lowest values among eight stations. Since the benzo [g, h, i] perylene is lower than the detection levels in many stations. The main origins of PAHs were found as both pyrolytic and petrogenic at most stations.
Development of a Liquid Chromatographic Method for Apomorphine Hydrochloride Quantitation in the Active Pharmaceutical Ingredients and in the Dosage Forms
Authors: AYDIN Beyza Sultan , BULDUK İbrahim
Published: December 2021

Apomorphine is currently used as a dopamine agonist to treat advanced Parkinson Disease. In the present study, we developed a sensitive, simple, reliable, and robust HPLC method for quality control of apomorphine hydrochloride in bulk drug and pharmaceutical formulations. C18 column was used for separation. Isocratic elution was performed using mobile phase A: 50 mM potassium dihydrogen phosphate solution (pH:3 with ortho-phosphoric acid), B: acetonitrile in the ratio of 85:15 (A: B), and the mobile-phase flow rate was kept at 1 mL min-1. Analyses were carried out at 272 nm using a UV detector. A perfect linear relationship between peak-area versus drug concentration in the range of 10‑100 μg mL-1 was observed (r2, 0.9999). It has been found that the developed method is sensitive (Detection and quantification limits were determined as 1.3 μg mL-1 and 3.8 μg mL-1, respectively), precise (RSD
Nanoteknoloji Uygulamalarında Hayatımıza Yansımalar
Authors: TÜYLEK Zülfü
Published: December 2021

Temel bilimler, eğitim, araştırma, üretim geçişi ve teknoloji transferi unsurlarını yeni ve faydalı ürünlere dönüştürerek yeni teknolojiler geliştirilmektedir. Yeni teknolojiler sayesinde akademisyenler, öğrenciler, endüstriyel araştırmacılar ve üreticiler ortak çalışma alanlarında bir araya geliyor. Bu yaklaşım sayesinde farklı teknolojilerin ortaya çıktığı görülmektedir. Geliştirilecek bu işbirlikleri sayesinde ileri teknolojiler ortaya çıkacaktır. Bu şekilde ortaya çıkan teknolojilerden biri de nanoteknolojidir. Bugün bilim adamları nanoteknolojinin insan yaşamını kökten değiştireceği görüşüne sahiptir. Bu da nanoteknolojideki güncel gelişmeler ve uygulamalar hakkında bir farkındalık yaratır. Aynı zamanda gelecekteki teknolojileri yönlendirecek bir teknolojik gelişme olarak da görülmektedir. Bu amaçla son yıllarda mukozal uygulama sırasında ortaya çıkan çeşitli sınırlamaların üstesinden gelmek için nanoteknoloji tabanlı ilaç verme sistemlerinin burun içi ilaç dağıtımına uygulanmaya başlandığı gözlenmiştir. Bu uygulamalardaki gelişmeler sayesinde etkili ilaç teslimatının mümkün olduğu aşamaya geçme konusunda ilerleme sağlanmıştır. Nanotıp temelinde geliştirilen ve şu anda klinik denemelerden geçen aşılar ve terapötik ilaçlar, COVID-19 ile mücadele için yenilikçi alternatifler olma potansiyeli sunuyor.

Nanoteknoloji, kendisini yaratan ve geliştiren dinamik koşullar altında hareket eder ve bu onun gelişimi için çok önemlidir. Tam anlamıyla gelişimlerini tamamlamadan bir üst aşama olan üretim işlemleri ile karşı karşıya kaldıkları görülmektedir. Bu durum, yeni teknolojiler açısından bir dezavantaj olarak görülmektedir. Bu teknolojinin tüm dünyada henüz emekleme aşamasında olduğu ve gelişmiş ülkelerde bile çeşitli sosyal sancılara neden olduğu düşünüldüğünde, olumsuzlukların bulunması normal olarak kabul edilmektedir.

Bu makalede, dinamik ve disiplinler arası yapısı ile öne çıkan yapısal malzemeler, gıda ve tarım, nano güvenlik, çevre ve su, sağlık alanı gibi birçok alanda nanoteknolojideki gelişmeler literatür taraması yapılarak tartışılacaktır.
Reaktif Orange 16 (RO16) boyarmaddesinin Ti/IrO2 karışık metaloksit elektrot kullanılarak giderimine destek elektrolit türünün etkisi
Authors: DELİKTAŞ Elif , YAVUZ Yusuf , KOPARAL Savaş
Published: December 2021

Tekstil ürünlerine olan talebin her geçen gün artması ile tekstil endüstrileri ve buna paralel olarak tekstil endüstrisi atıksuları hızla artarak dünyadaki en önemli endüstriyel kaynaklı atıksulardan birini oluşturmaktadır. Tekstil endüstrisi atıksularında karşılaşılan en büyük problem atıksuların yüksek miktarlarda boyar madde içermesidir. Boyama sürecinde elyafa yapışmadan atık suya karışan boyalar arıtılmadan alıcı ortama verildiklerinde renk oluşturmakta, estetik görünümü bozmakta ve suyun ışık geçirgenliğini azaltarak fotosentezi olumsuz yönde etkilemektedir. Bu nedenle bu atıksuların arıtılmaları daha da önemli hale gelmiştir.

Bu çalışmada Ti/IrO2 karışık metaloksit elektrotlarla Reaktif Orange 16 (RO16) boyarmaddesinin elektrokimyasal oksidasyon yöntemi ile renk giderimine destek elektrolit tür ve derişiminin katkısı araştırılmıştır. Destek elektrolit olarak Na2SO4, NaNO3 ve NaCl kullanılmıştır. Akım yoğunluğu, akış hızı, pH, başlangıç kirlilik derişimleri gibi parametreler belirlendikten sonra destek elektrolitlerin ortamdaki varlığı değerlendirilerek en uygun elektrolit türüne karar verilmiştir.

Başlangıç kirlilik derişiminin 30 mg/L olduğu model çalışma çözeltisinin Na2SO4 elektroliti ile elektrokimyasal oksidasyonunda 50 A/m2 akım yoğunluğu, 155,84 mL/dk akış hızı, pH11 ve 0,01 M elektrolit varlığında 90 dk’lık bir arıtım süresi sonunda %65 renk giderim verimi ve 1,7454 kwh/m3 enerji tüketimi elde edilmiştir. Başlangıç kirlilik derişiminin 30 mg/L olduğu model çalışma çözeltisinin NaNO3 elektroliti ile elektrokimyasal oksidasyonunda 50 A/m2 akım yoğunluğu, 155,84 mL/dk akış hızı, pH0(5,94) ve 0,01 M elektrolit varlığında 90 dk’lık bir arıtım süresi sonunda %51 renk giderim verimi ve 2,0534 kwh/m3 enerji tüketimi elde edilmiştir. Başlangıç kirlilik derişiminin 30 mg/L olduğu model çalışma çözeltisinin NaCl elektroliti ile elektrokimyasal oksidasyonunda 50 A/m2 akım yoğunluğu, 155,84 mL/dk akış hızı, pH0(5,71) ve 0,05 M elektrolit varlığında 20 dk’lık bir arıtım süresi sonunda ~%100 renk giderim verimi ve 0,6557 kwh/m3 enerji tüketimi elde edilmiştir.
Hatay İli Reyhanlı-Kumlu Bölgesi Topraklarının pH, Kireç ve Organik Madde İçeriklerinin Belirlenmesi
Authors: YALÇIN Mehmet
Published: December 2021

Bu çalışmada Hatay ili Reyhanlı-Kumlu bölgesi topraklarının pH, kireç ve organik madde içeriklerinin belirlenmesi amaçlanmıştır. Bu amaç için çalışma alanı topraklarını temsil edecek şekilde iki farklı derinlikten (0-20 ve 20-40 cm) ve 40 ayrı noktadan olmak üzere toplamda 80 toprak örneği alınmıştır. Örneklerde toprakların pH, kireç ve organik madde içerikleri belirlenmiştir. Araştırma sonuçlarına göre; toprakların pH içerikleri 6.86-8.44 arasında değişmekte olup toprak örneklerinin pH’ları nötr ile hafif alkalin arasında değişmekle birlikte, alınan toprakların % 30.00’u nötr ve % 70.00’i ise hafif alkalin özellikte olduğu görülmüştür. Reyhanlı-Kumlu bölgesi topraklarının kireç içerikleri % 2.71-64.23 olup kireç içerikleri kireçli ile çok fazla kireçli arasında değişmekle birlikte, toprakların % 7.50’si kireçli, % 27.50’si orta kireçli, % 30.00’u fazla kireçli ve % 35.00’i ise çok fazla kireçli görülmüştür. Çalışma alanı topraklarının organik madde içerikleri % 0.40-2.89 arasında olup toprak örneklerinin organik maddeleri çok az ile orta arasında değişmekle birlikte, toprakların % 3.75’i çok az, % 78.75’i az ve % 17.50’si ise orta oranda organik madde görülmüştür. Toprakların kireç ile organik madde içeriği arasında pozitif önemli ilişki belirlenmiş olup, pH içeriği ile diğer özellikler arasında önemli ilişkiler belirlenememiştir.
Physics Teacher's Misconceptions About Direct Current Material
Authors: Afifah Yuliani Adhim  , Budi Jatmiko  , Tjipto Prastowo
Published: December 2021

The teacher's conception is one of the misconceptions that students encounter, so it is critical to uncover the status of the teacher's conception in order to improve the students' conception. The purpose of this study is to identify physic’s teachers misconceptions about direct current material. There were 16 Physics Teachers in one of the districts in East Java, including 7 (seven) teachers from the Public High School (Negeri) and 9 (nine) teachers from private schools (Swasta). This research is a quantitative descriptive analysis research. A three-tier diagnostic test was used to analyze the data, which revealed that the average percentage of misconceptions faced by teachers was 58% in a medium category. The results also showed that physics teachers had the highest rate of misconceptions in the Potential Difference sub-concepts (94%), while the Series Circuit concept had the lowest proportion of misconceptions (25,50%). misconceptions experienced by physics teachers must be addressed immediately, because it will have an impact on students' conceptions. The results of this study are very important for policy makers, especially the Education Office to find solutions in breaking the chain of physics misconceptions
Teachers' and Students' Perceptions of Online Learning Interactions Amidst the COVID-19 Pandemic in Indonesian Senior High Schools
Authors: Angen Yudho Kisworo  , Oktaviani
Published: December 2021

The research investigates Indonesian high school teachers' and students' perceptions of learning interactions when the classroom settings were moved online at the beginning of 2020. Conducting this research is essential to unpack the development of online learning after more than a year of pandemic hits in the world. To unload the issue, this research employed a mixed-method design. A survey questionnaire was shared with the teachers around Indonesia, and from this effort, 136 teachers and 107 students agreed to participate in this research. Then, two teachers and two students were chosen to explain in detail their online learning experience. Based on the results, teachers tend to positively perceive online learning, while students moderately perceive the learning. Five interaction aspects influence perceptions: social interaction, instructional interaction, technology interaction, teachers' and students' engagement. The findings suggest that teachers should be more active in enhancing their pedagogical practice and social approach in online classrooms.
Validation of The Mobile Training Management to Improve The Quality Results Training
Authors: Anak Agung Ngurah Ade Dwi Putra Yuda  , Bambang Suratman  , Yatim Riyanto
Published: December 2021

The success of the training can be seen from how the activation process takes place. One of them is by designing an innovative training model. This research aims to analyze results validation of the mobile training management model. This research uses descriptive quantitative analysis in determining the level of validation of research instruments. This research method uses descriptive quantitative research to assess the level of validation of the research instrument. The sample of this research is the participants of basic level seafaring training at the Surabaya Shipping Polytechnic, the Director of the Surabaya Shipping Polytechnic, and local government employees related to mobile training activities. The research was analyzed based on results validation of the training and education management experts. The results reserach show that the mobile training model instrument is declared valid. Results of expert assessment from training management and managing education are categorized as good. This shows that the mobile training development model in improving the quality of education and training is worthy of further research.