bluuebunny/crossref_metadata_2025 huggingface dataset:
ІННОВАЦІЙНА ДІЯЛЬНІСТЬ В ГОТЕЛЬНО-РЕСТОРАННОМУ БІЗНЕСІ
Authors: Середа Наталія , Піюренко Ілона
Published: November 2023

У статті розкрито процес розвитку інноваційної діяльності в готельному і ресторанному бізнесі. Охарактеризовано інноваційну діяльність та реалізацію інноваційного проєкту готельно-ресторанних підприємств, яка здійснюється за допомогою інноваційного потенціалу. Автори зазначають, що наразі невизначеність майбутнього для кожного в Україні, в тому числі, і для власників бізнесу, стає умовною нормою існування. В дослідженні з’ясовано, що в більшості випадків готелі обирають вигідно пристосоване місце розташування, зважаючи на те, що сьогодні більша частина готельєрів зосереджують свою увагу як для туристів, так і для представників бізнесу. Доведено, що інноваційна діяльність готельного та ресторанного бізнесу – це діяльність щодо здійснення й організації інноваційного процесу, який передбачає формування, освоєння та поширення інновацій. Автори обґрунтовують інноваційну діяльність в сфері туристичного та готельно-ресторанного бізнесу, як таку, що орієнтована на створення нового або заміну наявного продукту.
КЛЮЧОВІ ХАРАКТЕРИСТИКИ КОРПОРАТИВНОЇ СОЦІАЛЬНОЇ ВІДПОВІДАЛЬНОСТІ ТА ОСОБЛИВОСТІ ЇЇ РОЗВИТКУ В КИТАЇ
Authors: Станасюк Наталія , Фей Мей
Published: November 2023

У статті узагальнено ключові характеристики корпоративної соціальної відповідальності (КСВ) на сучасному етапі, серед яких можна виокремити орієнтація на забезпечення сталого розвитку, вплив на міжнародну конкурентоспроможність та інвестиційну привабливість компанії, мотиваційний характер та тривекторний розвиток (економічний, соціальний, екологічний), універсалізація підходів до реалізації КСВ-практик у різних країнах, зростання державного регулювання цієї сфери, складність оцінювання кінцевих результатів. Розглянуто особливості поширення КСВ в Китаї. Виокремлено внутрішні і зовнішні чинники, які сприяли активізації КСВ в КНР. Виділено особливості КСВ в Китаї, а також спільні риси КСВ з європейською практикою. Акцентовано на вагомій ролі у просуванні КСВ в КНР з боку держави, зокрема через приведення у відповідність нормативно-правового забезпечення.
МОТИВУВАННЯ ЯК СКЛАДОВА МАРКЕТИНГОВОЇ ДІЯЛЬНОСТІ ПІДПРИЄМСТВА
Authors: Матвєєва Наталя , Пушкар Тетяна , Серьогіна Дар’я
Published: November 2023

В роботі розглянуто наукові підходи до висвітлення проблем аналітичного характеру щодо сучасного готельного підприємств в основі якого є базова концепція маркетингу, а саме: формування маркетингової діяльності. Цей підхід підкреслює важливість потреби цільових ринків і забезпечення задоволення на високому рівні за допомогою більш ефективних стратегій, ніж у конкурентів. Для досягнення позитивного результату необхідно належним чином розробити та реалізувати маркетингову політику підприємства, однією з ключових складових якої є мотивування працівників. Мотиваційний аспект зростає як система факторів, що стимулюють робочий колектив до досягнення стратегічних цілей підприємства шляхом формування певного сприйняття продукту або послуги споживачами. Враховуючи це, ретельний аналіз мотивування забезпечує збалансованість управління внутрішніми та зовнішніми факторами підприємства.
COMPARATIVE CHARACTERISTICS OF THE MANAGERIAL AND ECONOMIC ASPECTS OF DIGITAL BUSINESS TRANSFORMATION
Authors: Zavrazhnyi Kostiantyn , Kulyk Anzhelika
Published: November 2023

Digital transformation is a key element of modern business that impacts its management and economic development. The article is dedicated to the analysis of the essence and importance of digital transformation in the context of managerial and economic aspects. The key factors and manifestations of digital transformation in the business environment are studied, particularly its impact on business models, internal work processes and interaction with consumers. It has been determined that new digital platforms and services can create innovative ways to generate revenue and attract new customers. The article focuses on strategic planning as a necessary stage before the implementation of digital transformation. Before implementing digital initiatives, it is extremely important to conduct an analysis, clearly define goals and objectives, and understand how they will be integrated into the overall development strategy of the company. The study confirmed that leadership plays a critical role in the process of implementing technology initiatives. The effective contribution of leadership involves its active engagement in this process, facilitating the adoption of well-founded strategic decisions, and providing the necessary resources for the successful realization of initiatives. The article emphasizes that successful digital transformation requires not only technological changes, but also cultural ones, corporate culture should be aimed at accepting changes and being ready to adapt to the new digital environment. Research shows that successful implementation of digital initiatives requires employees to develop new skills, as well as flexibility and readiness for constant change, not only for IT professionals, but also for all levels of staff. The article highlights the significance of collaboration and partnership in modern business during digital transformation, emphasizing the opportunities presented by digital technologies to enhance interaction with partners and increase the efficiency of business processes.
Phylogenetic analysis of a region of mitochondrial cox-1 as a DNA barcode marker sequence of Gazella subgutturosa (Goitered gazelle) in Mongolia
Authors: Bayarlkhagva M. , Ulziibat B. , Gun-Aajav B. , Bazarsad D. , Damdingiin B. , Batmagnai E.
Published: November 2023

Gazella subgutturosa, a vulnerable species, is threatened by illegal hunting for meat and sport. The mitochondrial cytochrome c oxidase subunit 1 gene (cox-1) is used as a DNA marker to distinguish mammalian species for the investigation of illegal hunting. In this study, we sequenced a part of the cox-1 gene (709 bp) of six Mongolian G. subgutturosa individuals. Our DNA sequences were clustered in a clade of Gazella which is distinct from other clades of mammalian species in the phylogenetic tree. Our findings suggest that DNA sequences can be useful in the investigation of illegal hunting.
Needs Analysis for Drama Scripts Based on The Syair Perang Menteng
Authors: Noviyanti  , Purnomo Mulyadi Eko , Nurhayati
Published: November 2023

This research aimed to analyze the needs of lecturers and students regarding the need to do drama scripts transformation based on Menteng Battle Verse, which was conducted at Sriwijaya University. The data collection of the needs analysis used interviews and questionnaires, and the respondents were 1 lecturer teaching a Palembang Malay Traditional Theatre course and 57 students of Indonesian Language and Literature Education Sriwijaya University. This research applied qualitative and quantitative research. Data analysis was carried out by reviewing the results of interviews and questionnaires. The components of the needs analysis included (1) students’ knowledge of Menteng Battle Verse, (2) Students’ knowledge of the content of Menteng Battle Verse, (3) students’ perspectives on the preservation of Menteng Battle Verse, and (4) drama script transformation based on Menteng Battle Verse. In conclusion, the result of the needs analysis showed that the lecturer and students needed to do a drama scripts transformation based on Menteng Battle Verse. The transformation was used as a pilot project for students to write a drama script based on the Menteng Battle Verse in the Palembang Malay Traditional Theatre course.
PENGARUH TERAPI PIJAT KAKI TERHADAP PENURUNAN TEKANAN DARAH PADA PENDERITA HIPERTENSI PRIMER DI WILAYAH KERJA PUSKESMAS CIGEMBLONG
Authors: Hakiki Beni Zaenal , Rakhmawati Arifah
Published: November 2023

Pendahuluan : Hipertensi merupakan penyakit tidak menular yang akhir-akhir ini menjadi masalah kesehatan yang meluas. Satu miliar orang di dunia menderita hipertensi dan 90-95% kasusnya tidak terdiagnosis dan diperkirakan akan meningkat menjadi 1,15 miliar kasus pada tahun 2025. Salah satu upaya untuk menurunkan tekanan darah adalah terapi pijat kaki, yaitu teknik relaksasi yang memungkinkan darah mengalir ke seluruh tubuh. berkat pelebaran pembuluh darah. Tujuan: Untuk mengetahui pengaruh terapi pijat kaki terhadap tekanan darah pada penderita hipertensi primer di wilayah kerja Puskesmas Cigemblong tahun 2022. Metode: Penelitian ini merupakan penelitian kuantitatif dengan menggunakan jenis penelitian pre-eksperimental, dengan One Group Pretest-Postest Design. Hasil: Rata-rata tekanan darah sistole dan diastole responden sebelum diberikan terapi pijat kaki sebesar 158,80/98,30 mmHg dan setelah diberikan terapi pijat kaki sebesar 144,63/89,87 mmHg, hasil uji statistik t-test berpasangan dan nilai p 0,000 (p-value = < 0,05), sehingga dapat disimpulkan bahwa terapi pijat kaki berpengaruh terhadap tekanan darah pada pasien. Kesimpulan: Penelitian ini dapat dijadikan sebagai dasar dalam pemberian terapi non farmakologi yakni terapi pijat kaki pada penderita hipertensi primer
DAMPAK PEMBELAJARAN DARING TERHADAP PERKEMBANGAN ANAK USIA PRA SEKOLAH: LITERATURE REVIEW
Authors: Mulyana Dede Sri , Idah Faridah
Published: November 2023

Pendahuluan : Pembelajaran adalah suatu upaya yang dilakukan oleh seseorang guru atau pendidik untuk membelajarkan siswa yang belajar. Pembelajaran daring merupakan pembelajaran yang berlangsung di dalam jaringan dimana pengajar dan yang diajar tidak bertatap muka secara langsung. Tujuan: untuk mengetahui dampak pembelajaran daring terhadap perkembangan anak usia prasekolah berdasarkan penelitian - penelitian yang sudah dilakukan sebelumnnya. Metode: Penelitian yang di gunakan yaitu literature review menggunakan tiga data base yaitu menggunakan Pubmed, Cochrane, dan Scholar untuk menemukan artikel sesuai kriteria inklusi dan ekslusi kemudian dilakukan review. Desain penelitian yaitu cross sectional, dengan tahun pencarian 2018-2022. Hasil: adanya dampak  yang signifikan  dari hasil pembelajaran daring terhadap perkembangan anak usia prasekolah, diantaranya yaitu adanya penurunan terhadap perkembangan psikososial, kognitif dan kecerdasan emosional anak usia prasekolah. Kesimpulan: Diharapkan perawat maupun tenaga medis lainnya dapat membantu
ASUHAN KEPERAWATAN DENGAN DEFISIT KESEHATAN KOMUNITAS: KURANG OPTIMALNYA PEMENUHAN NUTRISI PADA KELOMPOK USIA 0-5 TAHUN DENGAN INTERVENSI PENGEMBANGAN KESEHATAN KOMUNITAS DAN PROMOSI PERILAKU UPAYA KESEHATAN DI WILAYAH KERJA PUSKESMAS PUGER KABUPATEN JEMBER
Authors: Ummah Ririkh Farikhatul , Rasni Hanny , Wijaya Kristian Arisma
Published: November 2023

Pendahuluan : Tingginya angka prevalensi balita dengan stunting menyebabkan faktor masalah defisit kesehatan komunitas dalam pemenuhan nutrisi anak. Defisit kesehatan komunitas stunting merupakan masalah global, sehingga kebijakan penanganan stunting sendiri telah menjadi komitmen global. Namun program yang telah dibuat oleh pemerintah belum dapat berjalan secara optimal. Tujuan: Untuk mendapatkan gambaran asuhan keperawatan komunitas masalah defisit kesehatan komunitas kurang optimalnya pemenuhan nutrisi anak dengan intervensi pengembangan kesehatan masyarakat dan promosi perilaku upaya kesehatan di Wilayah Kerja Puskesmas Puger Kabupaten Jember. Metode: Jenis penelitian ini adalah deskriptif kualitatif dengan pendekatan studi kasus, teknik sampling menggunakan purposive sampling untuk menentukan informan sebagai narasumber Sampel penelitian yaitu kelompok umur 0-5 tahun. Sementara, teknik pengumpulan data terdiri atas wawancara mendalam dengan format pertanyaan terbuka, observasi langsung dan dokumen tertulis. Analisis data menggunakan asuhan keperawatan dengan pendekatan SDKI,SLKI, dan SIKI. Hasil: intervensi pengembangan kesehatan masyarakat dan promosi perilaku upaya kesehatan dapat meningkatkan status kesehatan komunitas dalam pemenuhan nutrisi anak. Kesimpulan: terdapat peningkatan ketersediaan program proteksi kesehatan, partisipasi dalam program kesehatan komunitas, kepatuhan terhadap standar kesehatan lingkungan, dan pemantauan standar kesehatan komunitas
PENGARUH EDUKASI KESEHATAN TERHADAP SELF CARE PASIEN DIABETES MELITUS TIPE 2
Authors: Rahman Zakiah
Published: November 2023

Pendahuluan : Diabetes melitus adalah penyakit kronis yang membutuhkan perawatan jangka panjang dengan mengurangi risiko multifaktorial selain kendali glikemik. Pengelolaan pasien dengan perawatan diri yang baik mengontrol kadar gula darah, tekanan darah, berat badan, dan lemak. Pendidikan kesehatan diabetes adalah bagian penting dari pengobatan DM tipe 2. Tujuan penelitian ini untuk mengetahui edukasi kesehatan berpengaruh terhadap self care pasien diabetes melitus tipe 2 di RS-BLUD Kota Tanjungpinang. Metode: Jenis penelitian kuantitatif dengan desain pre-experimental yang melibatkan satu grup pre- dan post-test. Jumlah sampel sebanyak 34 orang, dengan teknik pengambilan sampel consecutive sampling. Variabel dalam penelitian ini edukasi kesehatan (variabel independen) dan self care (variabel dependen). Alat pengumpulan data : kuesioner self-care SDSCA (Summary Of Diabetes Self-care Activities). Analisa Data : uji statistik Wilcoxon Rank. Hasil : Hasil penelitian sebelum dilakukan edukasi kesehatan sebagian besar responden memiliki status self care kurang sebanyak 21 orang (61,8%) dan status self care baik sebanyak 13 orang (38,2%). Sedangkan sesudah dilakukan edukasi kesehatan sebagian besar responden memiliki status self care kurang sebanyak 14 orang (41,2%) dan status self care baik sebanyak 20 orang (58,8%) dengan p Value 0,008. Kesimpulan: Terdapat pengaruh pemberian edukasi kesehatan terhadap self care pasien diabetes melitus tipe 2 di RS-BLUD Kota Tanjungpinang. Saran : Pasien diabetes melitus harus diberikan edukasi agar mereka mengetahui dan melakukan perawatan diri secara mandiri untuk menjaga kadar gula darah mereka dengan memantau kadar gula darah, melakukan aktifitas fisik, mengontrol pola makan, dan menjalani pengobatan
HUBUNGAN ANTARA TUGAS PERKEMBANGAN KELUARGA DAN TUGAS PERKEMBANGAN REMAJA DENGAN PERILAKU AGRESIF DI SMP NEGERI 2 PUNGGELAN
Authors: Rahmawati Dwi , Supriyadi
Published: November 2023

atar belakang: Perilaku agresif ialah perilaku yang merugikan secara verbal atau fisik yang cenderung merugikan orang lain dan bersifat destruktif. Terdapat 4 aspek perilaku agresif yakni fisik, verbal, dan permusuhan. Ada beberapa faktor yang mempengaruhi perilaku agresif salah satunya ialah faktor eksternal seperti pola asuh orang tua, keluarga, dan teman sebaya. Tujuan: Mengetahui hubungan antara tugas perkembangan keluarga dan tugas perkembangan remaja dengan perilaku agresif di SMP Negeri 2 Punggelan. Metode: Jenis penelitian ini adalah kuantitatif dengan mempergunakan metode deskriptif analitik melalui pendekatan cross-sectional. Metode sampling dalam penelitian ini yaitu Stratified random sampling dengan sampel yang digunakan yaitu 60 responden siswa SMP Negeri 2 Punggelan. Hasil: Hasil uji chi square hubungan tugas perkembangan keluarga dengan perilaku agresif didapatkan p-value = 0.000 (p < 0.05). Dan hubungan tugas perkembangan remaja dengan perilaku agresif didapatkan p-value = 0.001 (p < 0.05). Perolehan penelitian memperlihatkan bahwasanya terdapat hubungan yang signifikan antara tugas perkembangan keluarga dan tugas perkembangan remaja dengan perilaku agresif di SMP Negeri 2 Punggelan. Kesimpulan: Ada hubungan antara tugas perkembangan keluarga dan tugas perkembangan remaja dengan perilaku agresif di SMP Negeri 2 Punggelan.
The changing contributory role to infections of work, public transport, shopping, hospitality and leisure activities throughout the SARS-CoV-2 pandemic in England and Wales
Authors: Hoskins Susan , Beale Sarah , Nguyen Vincent G , Byrne Thomas , Yavlinsky Alexei , Kovar Jana , Fong Erica Wing Lam , Geismar Cyril , Navaratnam Annalan M. D. , van Tongeren Martie , Johnson Anne M. , Aldridge Robert W. , Hayward Andrew
Published: November 2023

Background Understanding how non-household activities contributed to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections under different levels of national health restrictions is vital. Methods Among adult Virus Watch participants in England and Wales, we used multivariable logistic regressions and adjusted-weighted population attributable fractions (aPAF) assessing the contribution of work, public transport, shopping, and hospitality and leisure activities to infections. Results Under restrictions, among 17,256 participants (502 infections), work [adjusted odds ratio (aOR) 2.01 (1.65–2.44), (aPAF) 30% (22–38%)] and transport [(aOR 1.15 (0.94–1.40), aPAF 5% (-3–12%)], were risk factors for SARS-CoV-2 but shopping, hospitality and leisure were not. Following the lifting of restrictions, among 11,413 participants (493 infections), work [(aOR 1.35 (1.11–1.64), aPAF 17% (6–26%)] and transport [(aOR 1.27 (1.04–1.57), aPAF 12% (2–22%)] contributed most, with indoor hospitality [(aOR 1.21 (0.98–1.48), aPAF 7% (-1–15%)] and leisure [(aOR 1.24 (1.02–1.51), aPAF 10% (1–18%)] increasing. During the Omicron variant, with individuals more socially engaged, among 11,964 participants (2335 infections), work [(aOR 1.28 (1.16–1.41), aPAF (11% (7–15%)] and transport [(aOR 1.16 (1.04–1.28), aPAF 6% (2–9%)] remained important but indoor hospitality [(aOR 1.43 (1.26–1.62), aPAF 20% (13–26%)] and leisure [(aOR 1.35 (1.22–1.48), aPAF 10% (7–14%)] dominated. Conclusions Work and public transport were important to transmissions throughout the pandemic with hospitality and leisure’s contribution increasing as restrictions were lifted, highlighting the importance of restricting leisure and hospitality alongside advising working from home, when facing a highly infectious and virulent respiratory infection.
Ergenlerin Gözünden Göç
Authors: Dursun Asiye
Published: November 2023

Göç tüm gelişim dönemleri üzerinde etkili olan bir yapıdır. Küreselleşen dünyada son zamanlarda farklı nedenlerle artan göç olayları dikkat çekmektedir. Bu süreçte toplumun yetişkinleri olmaya hazırlanan ergenlerin, göç algıları, göç yaşantıları, gelecek yaşamlarında göçe yönelik plan ve bakış açılarının da önem kazandığı söylenebilir. Bu nedenle bu araştırmada, ergenlerin göç algılarının araştırılması amaçlanmaktadır. Katılımcılar, 40 (%38) kız ve 65 (%62) erkek olmak üzere toplam 105 ergenden oluşmaktadır. Veriler, araştırmacının hazırladığı, kişisel bilgi formu ve nitel soru formu aracılığı ile toplanmıştır. Araştırmanın ilk kısmında göçe yönelik sorulan soruların betimsel analizleri sunulmuştur. Göç etmek isteyen katılımcıların gerekçeleri ve göçe yönelik algılarına yönelik veriler içinse içerik ve metafor analizi kullanılmıştır. Araştırma bulgularına bakıldığında, bazı ergenlerin ve ailelerinin göç yaşantısını geçirdikleri görülmüş ve ergenlerin bazılarının ileriye yönelik farklı gerekçelere dayanan göç planları olduğu bilgisine ulaşılmıştır. Ayrıca katılımcıların göçe dair oluşturduğu 102 farklı metafordan, keşif, kaçış, gurbet, başlangıç, değişim, ihtiyaç, zorlayıcı, hareketlilik şeklinde adlandırılan sekiz farklı kategori elde edilmiştir. Bu bulgular doğrultusunda öneriler sunulmuştur.
The Role of Vitamin A, Vitamin C and Vitamin E for Chemoprevention of Oral Leukoplakia
Authors: Islam Mohidul , Ali Mir Nowazesh , Anwar Rezwana Binte , Asaduzzaman Md , Islam A S M Ariful , Hussain Mahbub , Rahman Quazi Billur
Published: November 2023

Introduction: Oral leukoplakia is a prevalent oral mucosal lesion known to undergo malignant transformation, posing a significant public health concern worldwide, primarily attributable to tobacco use. This study aims to investigate the potential preventive effects of vitamins A, C, and E on oral leukoplakia. We conducted a cross-sectional study at the Department of Oral & Maxillofacial Surgery, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh, over a one-year period from March 2017 to March 2018.
Methods: Study Population: We enrolled a total of 43 patients diagnosed with oral leukoplakia attending the Outpatient Department (OPD) of the Oral & Maxillofacial Surgery Department. Data Collection: Patients were assessed at 6, 12, and 24-week intervals, during which data were collected using standardized data sheets. Lesion size was measured in square centimeters, and lesion color was recorded through photography. Adverse drug reactions were monitored based on patient complaints during follow-up.
Histopathological Evaluation: Histopathological evaluations were performed both before the study and at the conclusion of the study to assess any changes in tissue characteristics. Outcome Variables: The primary outcome variables of interest were clinical response, histopathological findings, and complications associated with the treatment.
Results: The study population had a mean age of 44.95±10.42 years, with an age range from 22 to 60 years. The male-to-female ratio was 1.3:1. The average duration of the lesions was 14.81±4.82 months, with a range of 6 to 24 months. Lesions were most commonly located in the right buccal mucosa (41.9%), followed by the left buccal mucosa (27.4%). The mean initial lesion size was 4.08±1.95 cm², ranging from 1 to 8 cm². After 24 weeks, 11.63% of patients showed complete improvement. All patients initially presented with white lesions, with a reduction to 97.7% after 6 weeks, 88.4% after 12 weeks, and 69.8% after 24 weeks. Mild adverse drug reactions were reported in 11.7% of patients after 6 weeks and 2.3% after 12 and 24 weeks. Complete remission was observed in 11.6% of patients, and moderate improvement (41–90%) in 37.3%. Notably, one-third of patients experienced a significant color change in their lesions, and adverse drug reactions decreased during subsequent follow-up.
Conclusion: This cross-sectional study indicates potential benefits of Vitamin A, Vitamin C, and Vitamin E in mitigating oral leukoplakia symptoms, such as reduced lesion size and color improvement, with fewer adverse reactions observed. However, larger, controlled trials are necessary to establish the definitive efficacy of this vitamin combination.
Update Dent. Coll. j: 2023; 13(2): 23-29
Penerapan Model Delikan dan CTL untuk Meningkatkan Prestasi Belajar Pancasila dan Pengembangan Karakter Mahasiswa PGSD FKIP Unib
Authors: Juarsa Osa Juarsa , Djuwita Puspa Djuwita
Published: November 2023

Penelitian ini bertujuan menganalisis peningkatan prestasi belajar Pancasila serta ketertanaman karakter pada diri mahasiswa dan mendekripsikan strategi yang paling tepat dilakukan melalui pembelajaran model delikan, dan CTL. Metode pendekatan menggunakan kaji tindak latar kelas atau clasroon action reserch . Penelitian  ini dilaksanakan di kelas 1A PGSD FKIP UNIB TA 2019/2020 dengan menggunakan sistem siklus.  Setiap siklusnya terdiri atas beberapa tahapan yaitu: (1) Perencanaan (planning); (2)  Pelaksanaan tindakan (action); (3) Pengamatan (observation); dan (4) Refleksi (reflection), Metode pengumpulan data yang digunakan adalah Observasi ,Tes Hasil Belajar, Wawancara. Metode Analisis Data dengan penilaian acuan patokan (PAP), analisa data hasil sebelum dan sesudah perlakuan/treatment digunakan statistik mean serta data yang tidak bisa dianalisa dengan rumus statistik akan dinarasikan kemudian diberi argumen. Hasil penelitian menunjukkan bahwa prestasi belajar mahasiswa dapat ditingkatkan dari rata-rata hasil belajar kelas 66,60 menjadi 83 serta terjadi ketertanaman karakter kedalam diri mahasiswa. Rata-rata skor hasil ceklis pengamatan perubahan karakter mahasiswa atas nilai-nilai yang terkandung dalam materi pembelajaran pada siklus 2 jauh lebik daripada pada siklus 1, dimana rata-rata skor pada siklus 1 sebesar 66,25 dan rata-rata skor pada siklus 2 sebesar 80,06. Peningkatan ini terjadi setelah mahasiswa diajak menggali nilai yang terkandung dalam materi yang dipelajari juga diajak untuk mamantau keterbiasaan melakukan, dan mengkaji dengan cara mengemukakan pertanyaan apa, mengapa, bagaimana, siapa, dimana dan kapan dilakukan serta kemana harus dipertanggungjawabkan serta dilakukan secara terus menerus.
Sentiment Analysis Komentar Berbahasa Bengkulu Menggunakan Long Short-Term Memory (LSTM)
Authors: Nurhaeni Safitri , Faurina Ruvita , Utama Ferzha Putra , Anggriani Kurnia
Published: November 2023

Salah satu jenis informasi yang bisa didapatkan dari media sosial adalah informasi sentimen. Sentimen memiliki arti pendapat dan pandangan masyarakat yang mengandung perasaan di dalamnya. Analisis sentimen dapat digunakan untuk menganalisis nilai sentimen apakah sentimen tersebut merupakan sentimen yang cenderung netral, negatif, atau positif. Pemodelan analisis sentimen untuk berbagai bahasa diperlukan karena setiap bahasa memiliki karakteristik dan keunikannya masing-masing, tidak terkecuali Bahasa Bengkulu. Pemodelan sentimen Bahasa Bengkulu belum tersedia, oleh karena itu pada penelitian ini akan dikembangkan model analisis sentimen Bahasa Bengkulu dengan menerapkan Long Short-Term Memory (LSTM) dan dilakukan eksperimen arsitektur Long Short-Term Memory (LSTM) untuk mendapatkan arsitektur yang menghasilkan nilai terbaik. Data yang digunakan dalam penelitian berjumlah 24.000 komentar berbahasa Bengkulu yang diperoleh dari media sosial Instagram, Twitter, dan Youtube. Penelitian eksperimen 1 menghasilkan nilai akurasi yang paling baik dibandingkan dengan hasil pengujian pada eksperimen lainnya, dengan nilai akurasi sebesar 0,87 dengan presicission bernilai 0,80, recall bernilai 0,82 dan F1-score bernilai 0,81.
Sistem Informasi Rekam Medis Asesmen Kebidanan Berbasis Web Menggunakan Metode Rapid Aplication Development (RAD)
Authors: Fajri Wahyu , Hardiani Tikaridha
Published: November 2023

Pihak RS PKU Muhammadiyah Gamping – Yogyakarta memiliki tujuan agar proses yang berkaitan dengan aspek administrasi dan dokumentasi segera didigitalisasikan. Petugas rekam medis di RS PKU Muhammadiyah Gamping – Yogyakarta khususnya pada bidang asesmen kebidanan masih menggunakan sistem manual dalam melakukan pengelolaan dan pembuatan laporan data pasien. Hal ini menyebabkan terjadinya keterlambatan penyampaian laporan data harian pasien dan berdampak pada penurunan pelayanan pada pasien. Untuk mengatasi hal tersebut, maka dibutuhkan perangkat pencatatan secara digital yaitu sistem informasi rekam medis berbasis web. Metode yang digunakan penulis dalam pengembangan sistem informasi ini yaitu menggunakan model RAD atau Rapid Aplication Development. Platform pemrograman menggunakan framework CodeIgniter 3 dan Bootstrap 4.6. Pengelolaan database menggunakan MySQL. Tujuan dari pembuatan sistem informasi rekam medis ini untuk mempermudah pengelolaan data pasien yang meliputi data pendaftaran pasien, data pencatatan rekam medis pasien, dan pengumpulan master data pasien. Sistem rekam medis ini diharapkan dapat meningkatkan  pelayanan asesmen kebidanan.
Penerapan Metode Markerless Based Augmented Reality Rumah Fatmawati Sebagai Destinasi Wisata Unggulan Kota Bengkulu
Authors: Darnita Yulia , Toyib Rozali
Published: November 2023

Sosok Ibu Fatmawati sangat dikenal sebagai ibu pertama dan penjahit bendera sangsaka merah putih sebagai bendera negara Indonesia, menjadi pendamping Ir.Soekarno sebelum kemerdekaan sampai akhir ayatnya, sesorang dinilai dari keluarga mana dibesarkan dan tempat tinggalnya sebagai cerminan seseorang khususnya rumah dan sudah ada upaya untuk memperkenal rumah tempat tinggal Ibu Fatmawati dengan melalui media informasi berupa selebaran/brosur, buku, paduan wisata dan buku, tetapi ini ini hanya menjangkau kalangan tertentu saja. Penggunaan teknologi Augmented Reality yang bersifat real time dengan metode markerless based yang disematkan di Smartphone Android memungkinkan banyak orang bisa mendownload aplikasi ini dan dapat mengeksplorasi benda-benda bersejarah yang ada di rumah sebelum mereka mengambil keputusan untuk berkunjung. Berdasarkan hasil pengujian pembuatan gambar 3 D menggunakan metode markerless ini lebih efektif dibandingkan dengan metode marker based dimana keberhasilannya lebih tinggi, jarak tidak menjadi masalah yang berarti serta penggunaannya tidak tergantung dari jenis handphone yang khusus.Kata Kunci: ibu fatmawati, rumah, augmented reality,  metode markerless based, smartphone android
Are acute changes after status epilepticus in immature rats persistent?
Authors: Suchomelová L , Kubová H , Haugvicová R , Druga R , Mareš P
Published: November 2023

Early consequences of lithium-pilocarpine convulsive status epilepticus (SE) were studied six days after this status had been induced in rat pups at the age of either 12 or 25 days. Studies of spontaneous EEG activity demonstrated the presence of epileptic phenomena (isolated spikes) in both hippocampus and cortex (cortical spikes were more expressed in the older group). There were no marked behavioral correlates of spikes and transition into the ictal phase was exceptional. The motor performance on a rotorod and a horizontal bar was the same in experimental and control rats of both ages. Behavior in the open field was changed in a reverse manner in the two age groups: the locomotor activity of rats with induced seizures at the age of 12 days was significantly lower than that of their control siblings, whereas animals undergoing status at the age of 25 days were hyperactive. In addition, they also exhibited increased exploratory activity (rearing) and their habituation to the open field was deranged. Nissl-stained brain sections demonstrated extensive brain damage in the older group in contrast to the negative findings in younger animals. EEG, behavioral and morphological changes induced by status epilepticus in developing rats persisted for 6 days after the status. They markedly differed according to the age of animals.
Improvement of the accuracy by the measurement of the electrical cell membrane parameters.
Authors: Rohlíček V , Rech F
Published: November 2023

The electrical parameters of the cell membrane are mostly estimated employing ac methods. The measurement is based on the analysis of the current(s) flowing through an access resistance and the membrane. A current/potential transducer is used at the input of the device. The parameters of this transducer, especially its feedback capacity, degrades the accuracy of the measurement and hence diminishes the suppression of mutual influences of the individual parameters. The paper suggests a possible software correction and is supplemented by remarks for practical application.
Preconditioning modulates susceptibility to ischemia-induced arrhythmias in the rat heart: the role of a-adrenergic stimulation and K(ATP) channels
Authors: Ravingerová T , Pancza D , Ziegelhoffer A , Styk J
Published: November 2023

A new concept of cardioprotection based on the exploitation of endogenous mechanisms is known as ischemic preconditioning (IPC). It has been hypothesized that substances released during brief ischemic stress (e.g. catecholamines) stimulate the receptors and trigger multiple cell signaling cascades. Opening of ATP-sensitive K+ channels [K(ATP)] has been suggested as a possible final step in the mechanisms of protection. In this study, the role of adrenergic activation was tested in Langendorff-perfused rat hearts subjected to test ischemia (TI; 30 min occlusion of LAD coronary artery) by: 1) mimicking IPC (5 min ischemia, 10 min reperfusion) with short-term (5 min) administration of norepinephrine (NE, 1 µM), 15 min prior to TI; 2) blockade with b- or a1-receptor antagonists, propranolol (10 µM) and prazosin (2 µM), respectively, applied 15 min prior to TI during IPC. The role of K(ATP) opening was examined by perfusion with a K(ATP) blocker glibenclamide (10 mM) during IPC. Both IPC and NE-induced PC effectively reduced the incidence of ventricular tachycardia (VT) to 33 % and 37 %, respectively, vs 100 % in the non-PC controls, whereby ventricular fibrillation (VF) was totally abolished by IPC and markedly suppressed by PC with NE (0 % and 10 %, respectively, vs 70 % in the non-PC hearts; P<0.05). The severity of arrhythmias (arrhythmia score, AS) was also markedly attenuated by both interventions (IPC: AS 1.7±0.4; NE-PC: AS 1.8±0.3 vs AS 4.1±0.2 in the controls; P<0.05). Protection was not suppressed by propranolol (VT 28 %; VF 14 %; AS 2.2±0.6), whereas prazosin reversed the protective effect of PC (VT 83 %; VF 67 %; AS 4.0±0.8). Antiarrhythmic protection afforded by NE-PC was abolished by pretreatment of rats with pertussis toxin (25 mg/kg, i.p.) given 48 h prior to the experiments. Glibenclamide did not suppress the IPC-induced protection. In conclusion, the sensitivity of the rat heart to ischemic arrhythmias can be modulated by IPC. Protection is mediated via stimulation of a1-adrenergic receptors coupled with Gi-proteins but glibenclamide-sensitive K(ATP) channels do not appear to be involved in the mechanisms of antiarrhythmic protection in this model.
Suramin affects capsaicin responses and capsaicin-noxious heat interactions in rat dorsal root ganglia neurons.
Authors: Vlachová V , Lyfenko A , Vyklický L , Orkand RK
Published: November 2023

The effect of suramin, an inhibitor of G protein regulated signalling, was studied on the membrane currents induced by noxious heat and by capsaicin in cultured dorsal root ganglia neurones isolated from neonatal rats. Whole-cell responses induced by a heat ramp (24-52 °C) were little affected by suramin. The noxious heat-activated currents were synergistically facilitated in the presence of 0.3 µM capsaicin 13.2-fold and 6.3-fold at 40 °C and 50 °C, respectively. In 65% of neurones, the capsaicin-induced facilitation was inhibited by 10 µM suramin to 35±6 % and 53±6 % of control at 40 °C and 50 °C (S.E.M., n=15). Suramin 30 µM caused a significant increase in the membrane current produced by a nearly maximal dose (1 µM) of capsaicin over the whole recorded temperature range (2.4-fold at 25 °C and 1.2-fold at 48 °C). The results demonstrate that suramin differentially affects the interaction between capsaicin and noxious heat in DRG neurones and thus suggest that distinct transduction pathways may participate in vanilloid receptor activation mechanisms.
Do generative artificial intelligence systems dream of electric sheep? The concept and conditions of protection of objects generated by generative artificial intelligence systems in Ukraine’
Authors: Zerov Kostiantyn
Published: November 2023

The publication provides an overview of the noveltiesof the Ukrainian legislation «On Copyright and Related Rights» (2023) regarding the peculiarities of protection of non-original objects generated by a computer program (generative artificial intelligence system) using sui generis law, in particular through the prism of exceptions and limitations in copyright.Ukraine has introduced one of the world's first models of the legal protection of AI output through a special sui generis legal regime. The author determines that the legislator sets forth three conditions for a non-original object generated by a computer program (generative artificial intelligence system) to be protected by law: The AI output must differ from existing similar objects; the AI output must be generated as a result of the operation of a computerprogram without the direct participation of an individual in the generation of this object; and the rights of third parties must be respected when generating a non-original object.It is established that the existing exceptions and restrictions in Ukrainian copyright (free making of copies of works to search for text and data included in or related to scientific publications for research purposes and temporary reproduction) will allow limited operation of generative artificial intelligence systems. However, it is necessary to consider that AI outputs do not unreasonably restrict the legitimate interests of the relevant copyright owners.In practice, the functioning of generative artificial intelligence systems demonstrates one of the general principles of civil law - freedom of contract through self-regulation of the distribution of intellectual property rights to AI outputs. The assumption is made that it is not necessary to establish the «default» attribution of rights to such objects at the legislative level.The author suggests that in the future, depending on the requirements of sustainable economic development and the balance of interests between society and the relevant subjects of law, the terms of the legal protection of rights to AI outputs may be changed.The author provides recommendations for improving this area's legal regulation and enhancing law enforcement's efficiency.
Economic analysis of trends and problems of the development of creative industries in Ukraine and the world
Authors: Mishchenko Iryna
Published: November 2023

The cultural and creative sectors of the world economyare an important pillar of all humanity. They are necessary for strengthening social cultural diversity, social cohesion, cultural development and moral education of the population. In addition, until 2019, the creative sector was characterized by strong dynamics of economic growth and a positive impact on other sectors of the economy. The contribution of the creative sector to the world economy was 3% of GDP in 2019. However, the COVID-19 crisis has had a devastating impact on the cultural and creative sectors for countries around the world. For Ukraine, the destructive impact on the economy, in particular on the creative industries, deepened with the beginning of the war and continues to this day.In dynamics over decades, the sector of creative industries has demonstrated an extraordinary ability to mobilize, both on a creative level and economically. However, it needs comprehensive state support, both with financial resources and state regulation to create favorable conditions for attracting private investment, improving the legal field for the protection of creators, as well as greater organizational support for creatorsin such critical moments for the country.The article provides a comparative economic analysis of the level of development of creative industries in the world, European countries, and Ukraine for the period from 2010 to 2021. For Ukraine, the analysis was conducted through the 2022, inclusive. Global trends, problems and prospects for development, both on a global scale and in Ukraine have been identified. Some problems of the creative industries functioning in the conditions of war are highlighted. Proposals were made regarding the introduction of the necessary measures of operational influence of state regulation and additional funding for comprehensive financial support of creators, which would be appropriate toapply in Ukraine, along with the improvement of legislation in the field of protection of intellectual property objects and the creation of favorable conditions for attracting investments in the field of Creative Industries.
Obligation to register Internet channels (YouTube, TikTok, Facebook) and the legal situation of creators on the audiovisual market according to Polish and European Union law
Authors: Niewęgłowski Adrian
Published: November 2023

European Union law has introduced a duty for creators engaged in the business of providing various types of on-demand audiovisual content to register. In practice, this duty applies to individuals running audiovisual channels on platforms such as You Tube and similar platforms. The people concerned are very different, providing content of an educational nature (platforms for learning foreign languages, e.g. English, Spanish). The registration duty is also to be extended to those who also provide typically entertaining channels on digital platforms (e.g. reviews of films, books, computer games, comics). These individuals include creators, i.e. entities that provide certain intellectual content to the Internet protected, for example, by copyright and related rights. Relevant registers are to be kept in member states by public administration bodies, such as the National Broadcasting Council in Poland. The purpose of the above duty is increased control over the safety of content provided to the Internet (e.g. from the point of view of whether it is suitable for children or whether it does not contain hate speech). In addition, the purpose of the said duty is also to control whether the owners of channels on YouTube, Tik-Tok, etc. properly settle the income they earn through published content. The Polish legislator wants to propose new legal solutions in this respect. This is because the European Union legislator has introduced certain requirements, but has not determined how they would be implemented. The presentation of the experience of the Polish legislator may be interesting for the Ukrainian viewer, especially in view of Ukraine's aspirations to become a member of the European Union. If Ukraine joins the European Union, it will be obliged to implement relevant solutions in this respect. In this article, I have tried to show that the issue of registration of persons providing audiovisual media services is a new problem in the European Union, raising considerable public concern. The obligation to register audiovisualmedia service providers should not be too broad and cover providers that have a small audience or publish new content irregularly. Therefore, it is important to introduce clear criteria for which audiovisual media service providers should be registered.
Individual and combined associations of estimated pulse wave velocity and systemic inflammation response index with risk of stroke in middle-aged and older Chinese adults: a prospective cohort study
Authors: Xu Man , Wang Wenqiang , Chen Ruoling , Zhou Li , Hu Hui , Qiao Guiyuan , Wang Ling , Liu Xuezhen , Wang Qiuhong , Ai Yating , Ren Hairong , Hu Ping
Published: November 2023

Background and aims

Estimated pulse wave velocity (ePWV) and systemic inflammatory response index (SIRI) have been recently investigated as a marker of arterial stiffness and a novel systemic inflammatory indicator. This study aims to examine the independent and combined association of ePWV and SIRI with incident stroke and its subtypes.

Methods

Data of the Dongfeng-Tongji cohort study was analyzed for 9,154 middle-aged and older adults, who were free of cardiovascular disease and cancer and were followed up to document incident stroke. But their association with incident stroke events and its subtypes have not been well studied. Multivariable adjusted Cox regression models were used to determine the independent and combined association of ePWV and SIRI with incident stroke events.

Results

Over a 7.22-year follow-up, the cohort documented 491 stroke cases (387 ischemic stroke and 104 hemorrhagic stroke). The multivariate adjusted model showed that with each one-unit increase in the level of ePWV, the corresponding hazard ratios (HRs) (95% CI) for total stroke, ischemic stroke, and hemorrhagic stroke were 1.53 (95% CI, 1.23–1.90), 1.42 (95% CI, 1.11–1.83), and 1.92 (95% CI, 1.21–3.03), respectively. Similarly, with each one-unit increase in log-transformed levels of SIRI, the corresponding HRs (95% CI) for total stroke, ischemic stroke, and hemorrhagic stroke were 1.23 (95% CI,1.04–1.47), 1.16 (95% CI, 0.96–1.41), and 1.52 (95% CI, 1.05–2.20), respectively. There appeared to be a combined effect of ePWV and SIRI on stroke; Participants with high levels of both ePWV and SIRI had a higher risk of total stroke and hemorrhagic stroke, with multiple adjusted HR of 2.43 (95% CI, 1.09–5.42). Additionally, the incorporation of ePWV in addition to traditional cardiovascular risk factors significantly improved the predictive accuracy for total stroke with C statistic increased from 0.684 (95% CI, 0.661–0.707) to 0.687 (95% CI, 0.664–0.710; x2 = 6.65; p for difference = 0.010), and (suggestively) for ischemic stroke with C statistic increased from 0.684 (95% CI, 0.659–0.71) to 0.691(95% CI, 0.666–0.717; x2 = 3.13, p for difference = 0.077), respectively.

Conclusions

The presence of both high ePWV and SIRI individually, as well as together, was found to be associated with an increased incidence of stroke. The combined stroke risk assessment using these two indicators could potentially improve non-invasive assessment and treatment strategies for high-risk patients, as these indicators are easily accessible in clinical practice.
Quantification of pulmonary perfusion using LSIM-CT correlates with pulmonary hemodynamics in patients with CTEPD
Authors: Yamaguchi Tomohiro , Ehara Shoichi , Yoshida Hisako , Himoto Daisuke , Izuta Shinichiro , Hayashi Ou , Hayashi Hiroya , Ogawa Mana , Shibata Atsushi , Yamazaki Takanori , Izumiya Yasuhiro , Fukuda Daiju
Published: November 2023

Background

Lung subtraction iodine mapping (LSIM)-CT is a clinically useful technique that can visualize pulmonary mal-perfusion in patients with chronic thromboembolic pulmonary disease (CTEPD). However, little is known about the associations of LSIM images with hemodynamic parameters of patients with CTEPD. This study investigates a parameter of LSIM images associated with mean pulmonary arterial pressure (mPAP) and validates the association between pulmonary vascular resistance, right atrial pressure, cardiac index, and exercise capacity in patients with CTEPD.

Methods

This single-center, prospective, observational study involved 30 patients diagnosed with CTEPD using lung perfusion scintigraphy. To examine the correlation of decreased pulmonary perfusion area (DPA) with mPAP, areas with 0–10, 0–15, 0–20, and 0–30 HU in lung subtraction images were adopted in statistical analysis. The DPA to total lung volume ratio (DPA ratio, %) was calculated as the ratio of each DPA volume to the total lung volume. To assess the correlation between DPA ratios of 0–10, 0–15, 0–20, and 0–30 HU and mPAP, Spearman's rank correlation coefficient was used.

Results

The DPA ratio of 0–10 HU had the most preferable correlation with mPAP than DPA ratios of 0–15, 0–20, and 0–30 HU (ρ = 0.440, P = 0.015). The DPA ratio of 0–10 HU significantly correlates with pulmonary vascular resistance (ρ = 0.445, P = 0.015). The receiver operating characteristic curve analysis indicated that the best cutoff value of the DPA ratio of 0–10 HU for the prediction of an mPAP of ≥30 mmHg was 8.5% (AUC, 0.773; 95% CI, 0.572–0.974; sensitivity, 83.3%; specificity, 75.0%). Multivariate linear regression analysis, which was adjusted for the main pulmonary arterial to ascending aortic diameter ratio and right ventricular to left ventricular diameter ratio, indicated that the DPA ratio of 0–10 HU was independently and significantly associated with mPAP (B = 89.7; 95% CI, 46.3–133.1, P < 0.001).

Conclusion

The DPA ratio calculated using LSIM-CT is possibly useful for estimating the hemodynamic status in patients with CTEPD.