bluuebunny/crossref_metadata_2025 huggingface dataset:
Transpyloric feeding with artificial lung ventilation in premature with pneumonia: an observational study
Authors: Smirnov O. G. , Gorbachev Vladimir I. , Novozhilov V. A.
Published: September 2023

INTRODUCTION: Feeding critically ill patients on mechanical ventilation through a gastric tube can be challenging. Parenteral nutrition is often preferred when enteral feeding is problematic. Transpyloric feeding has been identified as an optimal method of nutrition for seriously ill premature infants. OBJECTIVE: This study aims to evaluate the advantages of transpyloric feeding combined with artificial ventilation compared to gastric feeding in premature neonatal patients. MATERIALS AND METHODS: The study included 64 patients with low tolerance to enteral feeding who required mechanical ventilation. The gestational age of the patients did not exceed 34 (32–35) weeks. Enteral feeding using a NAN® mixture was administered through a feeding tube placed outside the pylorus with an anti-reflux mechanism. The volume of enteral feeding was determined based on the requirement of 120 kcal/kg/day. RESULTS: The results of the study demonstrated that the group receiving transpyloric feeding had a significantly shorter hospital stay of 54 (41–67) days compared to the group receiving gastric feeding with 86 (64–94) days, p < 0.05. The weight gain in the group receiving gastric feeding was significantly lower at 89 (55–200) g compared to the group receiving transpyloric feeding with 161.5 (110–218) g. Similar findings were observed regarding a decrease in total protein levels on the 10th day of the study in the gastric feeding group with 36.5 (32–40) g/l compared to the transpyloric feeding group with 47 (42–50) g/l, p < 0.05. CONCLUSION: Transpyloric nutrition in premature infants on mechanical ventilation is a more efficient method compared to gastric feeding. The findings suggest positive effects including reduced hospitalization duration, prevention of hypoproteinemia, and significant increase in body weight.
Reply to comment of V.A. Mazurok on the article of R.D. Komnov and A.A. Eremenko “Intellectual ventilation modes in Russian Federation: a short questionnaire survey”
Authors: Eremenko Aleksandr A. , Komnov R. D.
Published: September 2023

Ответ на комментарий В.А. Мазурка к статье Р.Д. Комнова и А.А. Еременко «Интеллектуальные режимы респираторной поддержки в Российской Федерации: результаты анкетного исследования»
Comparison of ultrasound signs, computed tomography data and morphological examination of the lungs in patients with coronavirus infection: post hoc analysis
Authors: Lakhin Roman E. , Zhirnova E. A. , Shchegolev A. V. , Zheleznyak I. S. , Chirsky V. S. , Pluminsky D. Y.
Published: September 2023

INTRODUCTION: Ultrasound examination (US) of the lungs has shown high efficiency in the diagnosis of COVID-19 pneumonia. The aim of the research was studying the correspondence of computed tomography (CT) US signs of the lungs and morphological data in patients with COVID-19 pneumonia. MATERIALS AND METHODS: The post hoc analysis included 388 patients who simultaneously underwent ultrasound and CT of the lungs. Lung ultrasound was performed according to the 16-zone “Russian Protocol”. Morphological data were obtained from the results of pathoanatomic examination of deceased patients. RESULTS: The comparison of signs detected by CT and ultrasound of the lungs was performed during a multidimensional correspondence analysis. The analysis was carried out using a three-dimensional solution that explained 64.9 % of inertia (p < 0.001). CT signs of “ground glass opacity” (100 %) corresponded to the B-line at ultrasound (100 %), CT of the consolidation sign (44.8 %) — ultrasound signs of consolidation (46.9 %), aerobronchogram of CT (34 %) — aerobronchogram of ultrasound (36.9 %), free liquid CT (11.1 %) — free liquid Ultrasound (13.9 %). CT signs of reticular changes (29.6 %) and “cobblestone pavement” (12.4 %) corresponded to various combinations of ultrasound signs of subpleural consolidation and B-lines. The B-lines were caused by the exudation of fluid and protein molecules into the intraalveolar space against the background of massive death of alveolocytes and formed by the development of intraalveolar edema and the formation of hyaline membranes. The ultrasonic sign of consolidation appeared in the airless zone of the lungs. Subpleural consolidation are caused by thickening and inflammatory infiltration of the pleura, diffuse alveolar damage, with intraalveolar edema, death and decay of alveolocytes, perivascular inflammatory cell reaction/ During treatment for more than 7 days, consolidation in the lung tissue developed due to the disorganization of the organ structure due to the progression of fibrosis. CONCLUSION: Multivariate correspondence analysis showed correlation of CT signs and US signs of the lungs. Morphological analysis showed polymorphism of histological data that caused the formation of ultrasound signs.
Comparison of noninvasive respiratory support methods in the postoperative period in cardiac surgery patients: a prospective randomized trial
Authors: Eremenko Aleksandr A. , Fomina D. V. , Komnov R. D. , Sorokina L. S. , Urbanov A. V.
Published: September 2023

INTRODUCTION: The frequency of respiratory failure in the postoperative period is 17–22 % [1–3]. The most commonly used methods: noninvasive positive pressure mask ventilation (NIPPMV), high-flow nasal cannula (HFNС), noninvasive positive pressure helmet ventilation (NIPPHV). OBJECTIVE: Comparison of the effectiveness of respiratory support methods depending on their effect on gas exchange in patients with mild to moderate respiratory failure in the early period after cardiac surgery. MATERIALS AND METHODS: The study included 42 cardiac surgery patients with 200 < P/F < 300 who were divided into 3 groups depending on the methods of respiratory support used (NIPPMV, HFNС, NIPPHV). The main point of the study is to assess the dynamics of the gas exchange indicators before, during and after their use. RESULTS: All three methods of NIVL contribute to a statistically significant improvement in gas exchange during NIVL, which persisted after the end of therapy (SpO2, PaO2, P/F, Qsp/Qt). In the group with the use of NIPPMV and HFNС an increase in the oxyhemoglobin fraction. In the course of this study, no data were revealed on changes in PaCO2. The largest increase in SpO2 was revealed in groups using a mask and helmet, but at the end of the NIVL session there were no statistically significant differences between the groups. A decrease in the proportion of patients with P/F < 300 after a single session in the NIPPMV group by 2 times, in the HFNC group — by 1.6 times, in the NIPPHV group — by 3.5 times. CONCLUSIONS: Conducting noninvasive respiratory support significantly improves the indicators of oxygenating lung function in the early postoperative period in cardiac surgery patients. NIPPHV and NIPPMV are more effective compared to HFNC. When using a helmet, a higher level of support is required.
't Hooft lines of ADE-type and topological quivers
Authors: Boujakhrout Youssra , Saidi El Hassan , Ahl Laamara Rachid , Btissam Drissi Lalla
Published: September 2023

We investigate 4D Chern-Simons theory with ADE gauge symmetries in the presence of interacting Wilson and ‘t Hooft line defects. We analyse the intrinsic properties of these lines’ coupling and explicate the building of oscillator-type Lax matrices verifying the RLL integrability equation. We propose gauge quiver diagrams Q_{G}^{\mu}Gμ encoding the topological data carried by the Lax operators and give several examples where Darboux coordinates are interpreted in terms of topological bi-fundamental matter. We exploit this graphical description (i) to give new results regarding solutions in representations beyond the fundamentals of sl_{N}slN, $ so_{2N}$ and e_{6,7}e6,7, and (ii) to classify the Lax operators for simply laced symmetries in a unified E_{7}7 CS theory. For quick access, a summary list of the leading topological quivers Q$ _{ADE}^{}$ is given in the conclusion section [Figures 29.(a-e), 30.(a-d) and 31.(a-d)].
Quem não cola não sai da escola?
Authors: Correia Eanes dos Santos , Cápua da Silva Charlot Veleida Anhai , Silva do Nascimento Willdson Robson
Published: September 2023

O artigo tem como objeto de estudo a questão subjetiva, a relação entre o saber dos estudantes e as bricolagens que eles sustentam nas aulas do ensino médio de uma escola estadual da cidade de Cumbe, Sergipe. Temos, como ponto de partida, duas questões: qual é a relação entre o saber dos estudantes e a bricolagem? Que sentido a cola tem para os estudantes? Utilizamos elementos da relação com o saber de Bernard Charlot, principalmente, desejo, posição subjetiva, figuras do aprender e relação epistêmica com o saber; e a noção de bricolagem a partir de Michel de Certeau. Conclui-se que cola é uma alternativa para a não reprovação do(a) estudante em uma determinada disciplina com a qual não tem afinidade ou sente dificuldade de estudar e aprender. É um dispositivo de motivação, com caráter de imediatez e mobilização, pelo fato de encontrar sentido em se sobressair às lógicas simbólicas da escola diante de uma prova escrita. Além disso, é um dispositivo de relação com o saber que confronta as normas e lógicas simbólicas da escola e de disciplinas específicas.
Desarrollo de la investigación sobre el emprendimiento social y el emprendedor social
Authors: Rodríguez García Jorge Santiago
Published: September 2023

En este artículo se pretende analizar, mediante técnicas derivadas de la bibliometría, el corpus de conocimiento relativo al emprendimiento social y al emprendedor social, con el fin de identificar la evolución de las publicaciones, el nivel de colaboración y la estructura social de este campo del conocimiento. Se busca contribuir al campo del emprendimiento social a través de un análisis bibliométrico de publicaciones académicas relacionadas con el emprendedor social en función de tres dimensiones: el desempeño, la colaboración y el mapeo científico (por análisis de cocitación). Para ello, se utilizó la aplicación del software libre Bibliometrix. El análisis confirma que, si bien es un área de conocimiento en auge, el estudio del emprendimiento social y del emprendedor social está en una etapa joven y es necesaria la generación de evidencia empírica que explique el papel y las características del emprendedor social en el entorno del emprendimiento social. La consulta se realizó únicamente con información de la base de datos Scopus, lo que implica que no se recuperó información de otras bases de datos importantes como Web of Science y otros repositorios de relevancia académica. Además, el término de búsqueda utilizado puede limitar la cantidad de publicaciones que analizar.
Publicar en revistas indexadas
Authors: Jiménez García Sara Aliria
Published: September 2023

En este trabajo se estudian nociones de ciencia que forman a los autores que publican en revistas indexadas, a través de una investigación documental, que abarcó 27 textos publicados entre 2011 y 2021 en revistas de Science Direct, por medio de dos categorías: las nociones que estos autores aprenden al escribir artículos y al ser evaluados a partir de tales ejercicios, y las que los forman al decidir en cuáles revistas publicar. Los resultados muestran que tales nociones adicionan algunos costos a la ciencia, privilegian el inglés sobre otras lenguas y crean publicaciones un cuanto más elitistas. Las conclusiones muestran que todavía es posible repensar dichas nociones o las métricas para evaluar investigadores, los costos de consultar y publicar en algunas revistas y la necesidad de citar a otros, ya que no es claro que propicien ciencia de frontera. Tanto la originalidad como las limitaciones de este ejercicio radican en que se presenta una mirada posible sobre estas nociones, pero se deja pendiente saber más sobre la manera en que se difunde el conocimiento científico.
At the Core of Institutional Care in Two Children’s Residential Homes (Mexico)
Authors: Razy Élodie
Published: September 2023

Este artículo examina lo que significa la institucionalización para los niños menores de cinco años en dos hogares de cuidado residencial para niños (casas cuna) en México a través de los conceptos de cuidado y agencia, a partir de la observación de que hay poca literatura sobre este tema en general y sobre la Ciudad de México, en particular. Faltan estudios empíricos y datos generales y estadísticos sobre los niños, las familias, los hogares, las historias institucionales de los niños y el personal. Este documento tiene como objetivo abordar esta brecha empírica mediante el estudio de la vida cotidiana de los niños. A partir de un trabajo de campo etnográfico de cinco meses y con un enfoque antropológico crítico reflexivo, se analizaron los entornos interpersonales y materiales (“espacios”) en los que se brinda atención utilizando el concepto de “institución total” de Goffman. Para contrastar estos hallazgos, se examinan los ajustes que hacen las trabajadoras de cuidado infantil y se explora más a fondo la “micro-agencia” que ejercen los niños a través del ejemplo de la vestimenta. Esto permite comprender mejor lo que se llama en este documento “contra-cuidado”, considerado como la participación activa, pero a menudo no reconocida, de los niños en su propio cuidado.
Epistemologia e estética:
Authors: Bechtlufft Bade Luiz Henrique , Couto Carreira Ricon Leandro
Published: September 2023

Epistemologia (compreendida, aqui, como teoria do conhecimento) e estética (compreendida, aqui, como possibilidade de estudo das experiências) são comumente considerados como separáveis um do outro, quando não incompatíveis entre si. Contudo, o que se observa nas produções de conhecimento que se desenvolvem nas humanidades é, precisamente, uma interação profunda e profícua entre os dois campos. Afinal, a obra produzida nos saberes das humanidades manifesta-se como um texto, que orienta a experiência de seus leitores de forma a produzir uma gama de conhecimentos. O presente artigo, nestes termos, procura analisar e explicitar algumas das relações possíveis entre estética e epistemologia, valendo-se da historiografia como representante das humanidades.
Grau de ansiedade entre acadêmicos de enfermagem durante a pandemia da Covid-19
Authors: Silva Jorge Luiz Lima da , Almeida Giulia Lemos de , Messias Cláudia Maria , Santos Daiana Alves dos
Published: September 2023

Introdução: diante do cenário pandêmico, os acadêmicos de enfermagem precisaram se adaptar e conviver habitualmente com sentimentos de medo e ansiedade, além da expressiva quantidade de profissionais da saúde infectados e mortos. Estas questões podem desencadear crises na formação, e sua resiliência influencia diretamente em sua qualidade de vida. Objetiva-se descrever o grau de ansiedade de acadêmicos de enfermagem de universidade federal, durante a pandemia de covid-19. Materiais e Métodos: estudo epidemiológico descritivo de desenho seccional. População foi composta por 187 acadêmicos de enfermagem, foi realizado cálculo amostral. Aplicado formulário disponibilizado de forma remota, com análise descritiva dos dados. Pesquisa aprovada pelo comité de ética sob o parecer 4.249.624. Resultados: apresentaram um grau de ansiedade mínima e leve em sua maioria, no entanto uma grande quantidade de alunos manifestou índices graves. Os sintomas mais frequentes, segundo o Inventário de Ansiedade de Beck, foram sensação de desequilíbrio, de desmaio e trêmulo, enquanto as questões de senso comum prevaleceram pensar demais, falta de paciência e preocupação constante. Discussão: estudos identificam como impacto de quarentenas e epidemias prévias, a ocorrência de distúrbios emocionais, depressão, irritabilidade e ansiedade.  Somando ainda, o estado de vulnerabilidade em que se encontram os graduandos de enfermagem, estando mais suscetíveis a desequilíbrios de ordem mental. Considerações finais: é essencial haver uma preocupação maior com a saúde mental dos graduandos e dos recém-formados. A ansiedade é natural, no entanto, a intensificação dos sintomas de ansiedade exige a busca por atendimento especializado.
Palavras-chave: Saúde Mental; Covid-19; Estudantes de Enfermagem; Enfermagem.
Nanomaterials in the Automobile Sector
Authors: Harun-Ur-Rashid M.
Published: September 2023

The automobile sector is continuously putting efforts into ensuring the safety and comfort of passengers, intelligent traffic guidance systems, pollution reduction, and successful recycling processes. The constructive and successful utilization of nanomaterials is an effective and potential scientific strategy that simplifies the technologies to develop lighter, more durable and economical, faster, and smart devices by consuming less raw materials and optimum energy. Emerging nanomaterials in the automobile sector explores how nanomaterials and nanotechnology are utilized to boost the performance of materials and devices required for automobile application by designing and developing nanocomposites, nanoalloys, nanocoatings, nanocatalysts, nanolubricants, and nanoadditives. In addition to these, this chapter will focus on the application of green polymer nanocomposites in automobile sector to address the issues associated with nanotoxicity.
The Effect of Acupuncture and Diet on Serum Leptin and Nesfatin-1 Levels in Overweight/Obese Individuals
Authors: AYDIN Tevhid , KUTLU Ruhuşen , BALTAOĞLU ALP Hayriye , KILINC İbrahim
Published: September 2023

Acupuncture applications and diet are frequently used in obesity treatment. We aimed to investigate the changes in serum leptin and nesfatin-1 levels measured before and after acupuncture and diet in overweight/obese individuals in the presented study. This interventional study was carried out on 90 overweight/obese patients. Participants were divided into three groups: Group 1 (Acupuncture), Group 2 (Diet), and Group 3 (Those who did not take any attempts to lose weight- control group). Serum leptin and nesfatin-1 levels were measured before and after the intervention.
The 30th days leptin values were significantly decreased in the acupuncture group (p=0.040) while they were significantly increased in the control group (p=0.039). It was detected that the nesfatin-1 values were significantly increased in both acupuncture (p=0.032) and diet groups (p=0.017). Also, body weights significantly decreased both in acupuncture (p=0.032) and diet groups (p<0.001). Our results support the effects of acupuncture treatment on appetite hormones. Further research on the mechanisms of endogenous and exogenous actions of the recently discovered hormones, leptin and nesfatin-1, are needed.
IMPLEMENTATION OF ONLINE REGISTRATION E-COURT AT INDONESIA RELIGIOUS COURTS
Authors: Muhammad Mukmin , Rahmadina Rahmadina
Published: September 2023

The purpose of this study is to know the pattern of service at the Barru Religious Court Office during the Covid-19 pandemic and the implementation of online case registration E-Court of physical distancing at the Religious Court Office during the pandemic. This qualitative research include observation, interviews, documentation. Data analysis involve data reduction, data presentation, and conclusion drafting. The result shows the implementation used in the registration of the first case is online case registration, the second is to get a down-payment interpretation online, the third can make online payments, the fourth can conduct trials online (litigation), the fifth can view calls online, and the sixth can make decisions online. The case registration E-Court has been carried out following PERMA No.1 of 2019 about the electronic case of registration. In particular, at a time when Indonesians are growing more concerned about the Covid-19 virus outbreak, this PERMA is extremely appropriate to be carried out.
INVESTMENT COURT SYSTEM SEBAGAI ALTERNATIF PENYELESAIAN SENGKETA PENANAMAN MODAL ASING
Authors: Kinanti Fatma Muthia , Wiko Garuda
Published: September 2023

Investment Court System (ICS) proposed by the European Union (EU) has been ratified through Bilateral Investment Treaty (BIT) between the EU and several partner countries such as Canada, Vietnam and Singapore. A study is needed to get an idea on the ICS mechanism. This is a normative research. The result shows that although there is a mechanism that is not in accordance with the concept of arbitration, the ICS decision is enforced as an arbitration award and is subject to the 1958 New York Convention. Indonesia as one of the countries currently still negotiating with the EU in the formation of an FTA is also still reviewing the adoption of ICS into the text agreement. In addition, although the background and objectives of the ICS are positive, there are still some points of weakness in the provisions of the ICS that will result in obstacles in their implementation which can be seen from the legal, political and technical side.
Schuld en schaamte sociologisch bezien
Authors: Dekker W.H.
Published: September 2023

Is shame in late modernity more important than guilt? In this article I look for answers to this question by analysing the main contributions of sociological theorists to the late modernity debate. The most dominant vision is that shame is taking the place of guiltin the life of an individual, especially when he does not reach the goals set by himself. Sociologists who have a more structuralist vision on society, stress that feelings of shame are the result of the dominant discourse on gender, success and career in our neoliberal society. Hartmut Rosa links shame to social alienation, one of the newest contributions to the debate. He pleads for resonance as a better and a more receptive way to connect to the world. An interesting point of view and helpful to give way to a moretheological approach to shame, guilt and salvation.
Value chain-based development plan for the calamansi (Citrus microcarpa) industry
Authors: Quijano Ma. Florisa T.
Published: September 2023

Calamansi, a staple condiment in Filipino cuisine, plays a pivotal role in the culinary heritage of the Philippines. The province of Nueva Ecija, situated in Central Luzon, has emerged as the primary producer of calamansi in the region. This study investigates the calamansi industry's dynamics in Nueva Ecija over a six-year period, encompassing 18 municipalities. A comprehensive analysis reveals that 756,136 calamansi trees are cultivated across 1,200 hectares of land, involving 1,481 farmers. Regrettably, both production and cultivation area have witnessed a declining trend during this period, with annual negative growth rates of -3.83% and -0.68%, respectively. Motivated by this concerning scenario, the researcher, a native of Nueva Ecija and a farmer, embarked on an agribusiness research endeavor. Employing a descriptive research approach and value chain analysis, this study scrutinizes the current state of the calamansi industry. Primary data were collected from 50 calamansi growers, while secondary sources included provincial, city, and municipal agriculturists from relevant local government units. The findings unveil key challenges faced by calamansi growers, including high input costs, price manipulation by intermediaries and traders, price fluctuations, and losses due to pest infestations and adverse weather conditions. To enhance competitiveness and ensure the industry's stability, collaborative efforts along the value chain are imperative. This study underscores the need for collective action to promote the sustainability of the calamansi industry in Nueva Ecija, highlighting opportunities for growth and development.
Toward Personalized Medicine Approaches for Parkinson Disease Using Digital Technologies
Authors: Khanna Amit , Jones Graham
Published: September 2023

Parkinson disease (PD) is a complex neurodegenerative disorder that afflicts over 10 million people worldwide, resulting in debilitating motor and cognitive impairment. In the United States alone (with approximately 1 million cases), the economic burden for treating and caring for persons with PD exceeds US $50 billion and myriad therapeutic approaches are under development, including both symptomatic- and disease-modifying agents. The challenges presented in addressing PD are compounded by observations that numerous, statistically distinct patient phenotypes present with a wide variety of motor and nonmotor symptomatic profiles, varying responses to current standard-of-care symptom-alleviating medications (L-DOPA and dopaminergic agonists), and different disease trajectories. The existence of these differing phenotypes highlights the opportunities in personalized approaches to symptom management and disease control. The prodromal period of PD can span across several decades, allowing the potential to leverage the unique array of composite symptoms presented to trigger early interventions. This may be especially beneficial as disease progression in PD (alongside Alzheimer disease and Huntington disease) may be influenced by biological processes such as oxidative stress, offering the potential for individual lifestyle factors to be tailored to delay disease onset. In this viewpoint, we offer potential scenarios where emerging diagnostic and monitoring strategies might be tailored to the individual patient under the tenets of P4 medicine (predict, prevent, personalize, and participate). These approaches may be especially relevant as the causative factors and biochemical pathways responsible for the observed neurodegeneration in patients with PD remain areas of fluid debate. The numerous observational patient cohorts established globally offer an excellent opportunity to test and refine approaches to detect, characterize, control, modify the course, and ultimately stop progression of this debilitating disease. Such approaches may also help development of parallel interventive strategies in other diseases such as Alzheimer disease and Huntington disease, which share common traits and etiologies with PD. In this overview, we highlight near-term opportunities to apply P4 medicine principles for patients with PD and introduce the concept of composite orthogonal patient monitoring.
HIV incidence and transactional sex among men who have sex with men in Ningbo, China: a prospective cohort study using WeChat-based platform (Preprint)
Authors: Hong Hang , Shi Xiaojun , Liu Yuhui , Fang Ting , Tang Chunlan , Xu Guozhang
Published: September 2023

BACKGROUND

Sexual transmission among men who have sex with men(MSM) has become the major HIV transmission route. However, little is known about the association between transactional sex(TS) and HIV incidence in China.

OBJECTIVE

This study aimed to investigate HIV incidence and distinguish sociodemographic and sexual behavioral risk factors associated with HIV incidence among MSM who engage in TS (MSM-TS) in China.

METHODS

We conducted a prospective cohort study using a WeChat-based platform to assess the HIV incidence among Chinese MSM, including MSM-TS in Ningbo, recruited from July 2019 until June 2022. At each visit, participants completed an online questionnaire and made an appointment for HIV counseling and testing on the Wechat-based platform before they had HIV tests offline. HIV incidence density was calculated as the number of HIV seroconversions divided by person-years(PYs) over the observed time, and univariate and multivariate Cox proportional hazards regression was conducted to identify factors associated with HIV incidence.

RESULTS

932 participants contributed 630.9 PYs of follow-up, and 25 HIV seroconversions occurred during the follow-up period, yielding an estimated HIV incidence of 4.0/100 PYs(95%CI:2.7~5.8). HIV incidence among MSM-TS was 18.4/100 PYs(95%CI:8.7~34.7), which was significantly higher than that of 3.2/100 PYs(95%CI:2.1~5.0) among MSM who do not engage in TS (MSM-NTS). After adjusting for sociodemographic characteristics, factors associated with HIV acquisition were being MSM-TS (aHR=3.93,95% CI:1.29~11.93), having unprotected sex with men(aHR=10.35, 95%CI:2.25~47.69) and multiple male sex partners (aHR=3.43, 95%CI:1.22~9.64) in the past six months.

CONCLUSIONS

This study found that the incidence of HIV among MSM-TS in Ningbo was high. The risk factors associated with HIV incidence include TS, having unprotected sex with men and multiple male sex partners, emphasizing the need for developing new interventions and providing medical care, HIV testing, and pre-exposure prophylaxis for MSM, particularly MSM-TS.
Application and evaluation of online medication consultation of the Internet-based pharmacy service (Preprint)
Authors: Zhu Suyan , Xu Hongbin
Published: September 2023

BACKGROUND

With the rapid advancement of the internet, accessing medication information and seeking online consultations have become increasingly prevalent for recent years. Pharmacy consultation plays an important role in enhancing medication adherence and optimizing medication therapy.

OBJECTIVE

This article aims to understand the demographic characteristics of users engaging, types of consultation questions and classification of involved drugs in internet medication consultations to evaluate the accessibility and efficacy of Internet-based pharmacy consultation.

METHODS

Online medication consultations service based on internet hospital was established. Data collection took place between January 2021 and July 2023. Data including sex, age, types of consultation questions and classification of involved drugs were collected for all patients receiving medication consultation.

RESULTS

A total of 1122 medication consultations were collected, including 967 online consultations and 155 offline consultations. The age distribution of the Internet medication consultation population is mainly between 18-44 years old (78.90%), while the age distribution of the pharmaceutical outpatient department is relatively balanced. There are more female consultees than male consultees regardless of the form of medication consultation. For patients seeking for online medication consultation, the top five types of consultation questions involved drug dosage/administration(28.44%)，drug interaction(13.44%), drug availability(12.41%), adverse drug reactions (10.65%), and rational drug selection (8.17%).

CONCLUSIONS

Compared with traditional medication consultation, Internet-based pharmacy consultation represents a promising trend in the healthcare industry, offering convenience, accessibility, and personalized solutions to patients. However, due to the age differences of Internet users and the shortcomings of text communication, online consultation was not appropriate for patients with polypharmacy or complicated drug-related problems. Future research and initiatives should focus on tailoring online healthcare platforms to meet the specific needs of diverse user groups.
Social Capital and Slum Communities: How to Fulfill Their Basic Needs in Palembang City during The Covid-19 Pandemic
Authors: Izzudin Muhammad , Yunindyawati Yunindyawati , Wardana Candra , Wulandari Putri , Ibrahim Muhammad , Putri Tasya Amelia , Aryansah Januar Eko , Prabujaya Sena Putra
Published: September 2023

The problem of slum settlements is still a major problem faced in Indonesia and other developing countries. One of the triggers for the emergence of slum settlements is due to the high rate of population growth, both through the birth process and the urbanization process. This study discusses the social capital of the people of the slum area of Palembang City in fulfilling basic needs, precisely in the 12 Ulu Village Area, Palembang City during the Covid-19 pandemic. This research uses a qualitative approach with a descriptive method. Sampling used a purposive sampling method with data collection using observation techniques and in-depth interviews. The study's findings indicate that (1) a high level of social capital as measured by networks, norms, and beliefs enables slum communities to survive the COVID-19 pandemic, and (2) the slum area communities' strategy for survival is to utilize yard land, home industries, social gathering, recitation, and mutual cooperation. There are several policy implications from this research: (1) Strengthen social capital, (2) Enhance community engagement, (3) Targeted support for vulnerable groups, (4) Ensure food security and (5) Strengthen social safety nets.
The Socio-Entrepreneurship Potential of Migrant Workers during the Covid-19 Era: A Mapping Study in Suralaga, East Lombok
Authors: Hamdi Saipul , Inderasari Oryza Peneumatica , Syarifuddin Syarifuddin , Sari Indah Firgina
Published: September 2023

The article aims to map the socio-entrepreneurship potential of migrant workers in the Covid-19 era. This mapping is vital to identify the potential that migrant workers have since they seek diversification during the pandemic years. In particular, this paper attempts to investigate the potential of this community as a socio-entrepreneurship resource for migrant workers as it has been seen essential an alternative approach to mitigating the effects of Covid-19. This study focuses on the Suralaga district, an area in East Lombok, which is known for a high number of migrant workers. This study is based on a qualitative approach and phenomenological methodology to gather and analyze data for six months (January–June 2022). There are 25 informants total in this study, 15 of whom are men and 10 of them are women. We used a variety of techniques to gather the data, including participant observation, in-depth interviews, focus groups, and documentation. The results of the study demonstrate that because of their low educational attainment—the majority of migrant employees having only completed elementary or junior high school—migrant workers have limited knowledge and skill, therefore it is difficult to find a job when they finished the contract and back home. In terms of natural potential, the Suralaga region's terrain is part of a farming area, where the majority of people work as farmers and grow tomatoes and chilies. The finding of this research also demonstrates the critical role that micro, small, and medium-sized businesses play in fostering the economic growth of migrant workers and serving as a counterweight to Covid-19's hegemonic middle class.
Study on Population Dynamics of Circumoncobothrium Sp. and Senga Sp. Parasitizing Freshwater Fish Mastacembelus armatus (Lacepede)
Authors: Gaikwad D. M.
Published: September 2023

Abstract: The present work deals with the study of population dynamics of Circumoncobothrium Sp. Shinde, 1968 and Senga Sp. Dollfus 1938, from Mastacembelus armatus from different places and fish market at Aurangabad and Beed region for the period of one annual cycle (July 2021 to June 2022). The percentage of incidence, intensity, density and index of infection is recorded along with the influence of seasons on these values during study period.
Proteomics and NGS Analysis of Induced Myeloid Leukemia Cells
Authors: Kumari Uma , Yadav K. Sreenath
Published: September 2023

Abstract: Induced myeloid leukemia cells have emerged as critical models for unraveling intricate molecular mechanisms of leukemogenesis. Integration of proteomics and Next-Generation Sequencing (NGS) analyses has yielded profound insights. Mcl1's significance in tumorigenesis and therapeutic resistance highlights Mcl-1 inhibitors' promise as anticancer agents. A selectively designed macrocyclic compound for Mcl-1 with high affinity, currently in clinical development, signifies a milestone in precision therapy. Activation of the Bak-dependent mitochondrial apoptotic pathway in acute myeloid leukemia offers novel insights into apoptotic regulation and potential interventions. Strikingly, complete tumor regression was achieved in diverse myeloma and acute myeloid leukemia models with a single tolerated dose of the compound, as monotherapy or combined with bortezomib or venetoclax, showcasing its therapeutic potential. Structural analyses through PyMOL and RasMol reveal intricate protein architecture, informing amino acid distributions, topology, and electrostatic profiles. These insights underpin understanding of protein functionality and intermolecular interactions. Simultaneously, multi-omics strategies, spanning genomics, epigenomics, transcriptomics, and proteomics, illuminate induced myeloid leukemia cells. These approaches uncover recurrent mutations, copy number variations, and fusion genes driving leukemogenesis. Epigenetic modifications, notably DNA methylation and chromatin remodeling, modulate gene expression in leukemic contexts.Together, these efforts underscore the significance of integrating diverse omics layers to decode leukemic transformation intricacies. The findings offer therapeutic prospects and insights into disease progression, fostering nuanced treatments across oncogenic landscapes beyond myeloid leukemia.
DESCRIÇÃO ANATÔMICA DOS ÓRGÃOS VEGETATIVOS AÉREOS DE Pachira aquatica Aubl. (MALVACEAE)
Authors: Rodrigues Pereira Fabiano , Novais Antunes Mariana , Leitão Carlos André Espolador
Published: September 2023

Pachira aquatica é uma árvore nativa da América do Sul utilizada na alimentação, obtenção de madeira e arborização urbana. Embora relativamente bem estudada, falta uma descrição estrutural detalhada dessa espécie. Portanto, o presente trabalho teve como objetivo descrever a anatomia dos órgãos vegetativos aéreos de P. aquatica crescendo no Semiárido Bahiano. Para este fim, foi utilizada metodologia usual em anatomia vegetal. A folha é palmaticomposta, hipoestomática, heterobárica, com mesofilo dorsiventral onde o parênquima lacunoso possui espaços intercelulares muito amplos. A nervura principal se projeta para ambas as faces e a de 2ª ordem apenas para a face adaxial. Na nervura principal ocorre uma fenda com tricomas secretores, tratando-se possivelmente de um nectário extrafloral. O pecíolo tem contorno circular em corte transversal. A vascularização consiste de um anel tetralobado de feixes vasculares colaterais. O caule em estrutura primária é pentalobado e possui braquiesclereides no córtex. Seus feixes vasculares são justapostos delimitando medula amilífera. Quando em estrutura secundária, o sistema axial do floema se organiza em grupos triangulares separados por raios centrifugamente mais abertos, quando observado em corte transversal. O lenho possui parênquima axial apotraqueal difuso a difuso em agregados. Os raios são uni ou multisseriados e heterocelulares. Ocorrem cristais do tipo drusa em todos os órgãos analisados. Também, idioblastos mucilaginosos longitudinalmente enfileirados nas nervuras de 1ª a 3ª ordem e no córtex e na medula do pecíolo e do caule. Conclui-se que P. aquatica tem características anatômicas adaptadas a ambientes úmidos bem como mais secos e seus órgãos em estrutura primária produzem abundante mucilagem. Sua madeira é aparentemente susceptível a trincas. Os órgãos analisados, pela facilidade no seccionamento a mão livre e pela variedade de estruturas interessantes, são um ótimo material para aulas práticas em anatomia vegetal.
ASSESSING KEY TECHNOLOGY FOR FACILITIES MANAGEMENT IN MALAYSIA
Authors: Abu Bakar Zulazhan , Kamaruzzaman Syahrul Nizam
Published: September 2023

The Facilities Management (FM) industry is seeing expansion and growth in Malaysia; nevertheless for the industry to elevate to a new level of success, it must overcome various technological barriers that have slowed its adoption of technology. The purpose of this research is to gain an understanding of the key technologies that the Malaysian market is prioritising and, consequently, to determine whether the industry is keeping pace with technological advancement. This study analysed the significance of ten (10) essential FM technologies and five (5) deployment FM areas with specific focus on real estate and commercial property sector in FM. The research employed purposive sampling to assemble an expert panel, and then used a questionnaire with a five-point Likert scale to conduct a Delphi study to evaluate the relative importance of each technology and implementation area. Each member of the expert panel was interviewed separately, and the survey was distributed to each of them. According to the findings, CMMS is identified as the technology with the most significant function as data and information management, and maintenance and operations management, whereas BAS is a significant technology for energy management. In conclusion, the research demonstrated that technology adoption in Malaysia is concentrated on legacy technology, hence emerging technology has not yet been considered due to factors such as untested use case, high risk on return on investment, the complexity of new technology and lack of organisational support. The implication of this study shows that adoption is still in its infancy stage; consequently, additional awareness, collaboration between academia and industry, investment in training, and prospects for industry efficiency and productivity are required. While the focus of the research is confined to real estate and commercial property, additional research can be conducted on other segments of the FM industry in Malaysia, including healthcare and education.
ASSESSING THE IMPACT OF SUBSTANCE ABUSE ON CONSTRUCTION PROJECTS IN JOS, NIGERIA
Authors: Sanda Yakubu Nehemiah , A. Anigbogu Natalia , D. Panshak Rhibetnaan , Bello Abdulganiyu
Published: September 2023

The use of drugs and other related substances in the construction industry is fast becoming a serious challenge. These substances when abused could have negative impact on the psyche of workers which affects the success of construction projects. This study therefore assesses the impact of substance abuse on construction projects with view to suggest possible measures for ameliorating those impacts towards successful project management. Questionnaire was used in collecting the data; mean score and charts were the instruments used in analysing the data. The major causes of substance abuse on construction sites were the stress of working long hours and pressure to meet up with strict deadlines. Substances commonly abused were locally brewed beer (burkutu), cannabis and prescription drugs such as emzol and tutoline. The rate of substance abuse among construction was adjudged to be high. Substance abuse affects workers’ ability to achieve project specifications, compromises clients’ satisfaction, causes cost and time overruns. The study suggests developing workplace drug and alcohol policies, pre-employment and random testing of workers and harsh punitive measures for offenders as effective strategies against substance abuse on construction sites in the study area.
USER SATISFACTION ON FACILITIES AND MAINTENANCE SERVICES OF STRATIFIED RESIDENTIAL BUILDINGS IN MALAYSIA
Authors: Che-Ghani Nor Zaimah , Myeda Nik Elyna , Ali Azlan Shah
Published: September 2023

This paper aims to investigate the performance of facilities and maintenance services provided in the four cases around Klang Valley for medium-cost stratified residential buildings. The quantitative methodology was adopted via questionnaire surveys to 137 residents of the four residential case study buildings. The analyses are frequency of failure, performance indicator by Weighted Average Satisfaction index (WAS) for the attributes: waiting time request and response from staff, professionalism and expertise of staff, worthiness of paid maintenance fee and relative performance index (RPIa) for the overall satisfaction for each facility as well as correlation test. Residents of the case studies were satisfied as the attributes of the performance recorded the WAS score of 40-79. The value of RPIa is closer to 1.00, indicating that almost all the facilities contribute to the good performance of the buildings and indirectly enhance the residents’ well-being. There is also a strong relationship between each attribute as the value of correlation is above 0.5 except for certain attributes in Case B. The present study suggests that maintenance services and facilities of residential buildings particularly should be in good condition and under proper care to enhance the performance of the buildings and the residents’ well-being. The study also noted that end user behaviour together with well-planned and functional management also contributes to the performance of the buildings.
Estudo comparativo sobre as escolhas lexicais no português moçambicano e brasileiro: o caso dos verbos e substantivos comuns
Authors: Santos Ivonete da Silva , Timbane Alexandre António
Published: September 2023

O léxico de uma língua é reflexo dos traços e marcas socioculturais do povo que a utiliza. O presente trabalho analisa as diferenças das escolhas lexicais no Português Brasileiro e no Português moçambicano. A pesquisa definiu os conceitos de léxico, explicou a influência da cultura nas escolhas e demonstrou os aspectos culturais e linguísticos que condicionam as variações linguísticas. O aporte teórico que sustentou a pesquisa baseia-se nos estudos de Bagno (2014), de Perini (2004), de Hall (2011), de Saussure (1995). Para a obtenção de dados distribui-se um questionário (via facebook) para vários inquiridos nos dois países. O questionário abordava as escolhas lexicais de verbos e substantivos. Da pesquisa se concluiu que as escolhas lexicais são condicionadas pela formação cultural e linguística do ser falante de uma determinada comunidade, pois o sistema linguístico permite a união e a intercompreensão entre falantes da lusofonia, mas existem características linguísticas específicas que não podem ser transferidas para outra variedade, porque a língua é cultura e o léxico só é compreendido semanticamente dentro do espaço geográfico onde ocorre.
Alfabetização: relações entre concepções e práticas
Authors: Da Silva Claudionor Alves
Published: September 2023

Este trabalho se insere no contexto de uma pesquisa intitulada “Alfabetização e Letramento Escolar: dasconcepções às práticas”, que investigou as relações entre as concepções de alfabetização, os referenciais teórico-metodológicos e as práticas pedagógicas das professoras alfabetizadoras. Neste trabalho propõe-se analisar as relações entre concepção de alfabetização e as práticas pedagógicas das professoras alfabetizadoras. Os dados foram coletados por meio da Observação e de Entrevista. Os sujeitos, participantes desta investigação foram vinte (20) professoras das classes de alfabetização (1º, 2º e 3º ano) de duas escolas da zona urbana do município de Vitória da Conquista – Ba. Constatou-se, neste trabalho, que a concepção de alfabetização da maioria das professoras não ultrapassa os limites da decodificação e cópia mecânica; há contradições e equívocos entre as concepções e as práticas pedagógicas de um grupo de professoras e, enfim, reina o mecanicismo no processo de ensino da leitura e da escrita.
Apresentação da 8ª Edição
Authors: Vieira Caio Aguiar , Guaresi Ronei
Published: September 2023

Apresentação da 8ª Edição
Abordagem didática para a análise linguística do conto “a moça tecelã”
Authors: Bazza Adélli Bortolon , E Silva Fernanda Trevizan , Montemezzo Helena Gabriela
Published: September 2023

Nas últimas décadas, houve muitas mudanças na forma de se compreender a educação e a linguagem. Partindo de uma visada interacionista, propôs-se reformular o trabalho em sala de aula. Em relação ao ensino da Língua Portuguesa, isso implicou trazer para o centro da prática o trabalho com os gêneros, de forma a aproximar a sala de aula com o cotidiano dos alunos. Além das atividades de leitura e escrita, que assumiram um caráter discursivo e mais concreto, o ensino da reflexão sobre a língua foi repensado. Em lugar da metodologia tradicional do ensino da gramática, teóricos e documentos oficiais (PCN, DCE) apontam o método da Análise Linguística como desejável e eficaz. Dessa forma, neste trabalho, propõe-se uma reflexão sobre possíveis aplicações do trabalho de Análise Linguística a o conto “A moça tecelã”, de Marina Colasanti. Como em uma perspectiva interacionista o trabalho com a língua se dá imbricado com o trabalho de leitura e de escrita, apresenta-se uma sequência didática em que se desenvolvem atividades de compreensão do texto, as quais culminam na reflexão sobre como determinadas expressões constroem sentidos (atividade epilinguística) e sobre como esses recursos podem ser classificados e sistematizados pelas teorias gramaticais (atividade metalinguística).