bluuebunny/crossref_metadata_2025 huggingface dataset:
Transforming Industrial Maintenance with Thermoelectric Energy Harvesting and NB-IoT: A Case Study in Oil Refinery Applications
Authors: Aragonés Raúl , Oliver Joan , Ferrer Carles
Published: January 2025

Heat-intensive industries (e.g., iron and steel, aluminum, cement) and explosive sectors (e.g., oil and gas, chemical, petrochemical) face challenges in achieving Industry 4.0 goals due to the widespread adoption of industrial Internet of Things (IIoT) technologies. Wireless solutions are favored in large facilities to reduce the costs and complexities of extensive wiring. However, conventional wireless devices powered by lithium batteries have limitations, including reduced lifespan in high-temperature environments and incompatibility with explosive atmospheres, leading to high maintenance costs. This paper presents a novel approach for energy-intensive and explosive industries, which represent over 40% of the gross production revenue (GPR) in several countries. The proposed solution uses residual heat to power ATEX-certified IIoT devices, eliminating the need for batteries and maintenance. These devices are designed for condition monitoring and predictive maintenance of rotating machinery, which is common in industrial settings. The study demonstrates the successful application of this technology, highlighting its potential to reduce costs and improve safety and efficiency in challenging industrial environments.
The Impact of α-Lipoic Acid Treatment on Multiple Sclerosis Disability: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Authors: Rodrigues Patrícia , Viero Fernanda Tibolla , Trevisan Gabriela
Published: January 2025

Background: Multiple sclerosis (MS) is a chronic inflammatory disease characterized by demyelination in the central nervous system (CNS). Despite the availability of interventions for disease exacerbations and symptomatic management, EM remained without a cure. Oxidative stress has been implicated in the MS demyelination mechanism. Adjuvant therapies like α-lipoic acid (ALA) have garnered interest for their potential to mitigate oxidative damage and control MS symptoms. ALA is found naturally in vegetables and red meat and can also be synthesized in mitochondria through enzymatic reactions involving octanoic acid and cysteine. However, its bioavailability from dietary sources is limited, prompting an investigation into supplemental forms. We conducted a systematic review and meta-analysis to assess the effect of ALA on disability in randomized clinical trials (RCTs) for MS. Methods: Records were searched until June 2023 (CRD42023397760). Five RCTs evaluated ALA’s effect on MS progression using the Expanded Disability Status Scale (EDSS). The quality of evidence was assessed using GRADE, and publication bias was evaluated using Egger’s and Begg’s tests. Results: Following the selection process, five studies were included involving 179 patients (87 placebo and 92 ALA). Oral administration of racemic ALA (R/S-ALA) at 600 mg twice daily reduced EDSS, indicating a potential for ALA supplementation to mitigate MS disability. The North American trials (SPMS patients) did not show heterogeneity, while Asian studies (RRMS patients) were moderated. The quality of evidence was high without publication bias. Conclusions: ALA treatment reduce EDSS scores. However, further studies are warranted to establish the role of ALA as an adjuvant in clinical practice in long-term follow-up (>2 years) RCTs.
Efficient Separation of Hydroxylamine from Metal Ions by PIM-ED Process
Authors: Yang Lilei , Ding Zhongwei , Zhu Zhengtao , Zhang Weidong
Published: January 2025

Selective separation of hydroxylamine (HA) from metal ions to prepare high-purity HA remains a challenge. In this study, given that HA can react with carbonyl compounds, TTA (thenoyltrifluoroacetone) was screened as a carrier to prepare the polymer inclusion membrane (PIM), which was used to separate HA from metal and inorganic acid ions. The experimental results demonstrated that the PIM exhibited good selectivity for HA. During the PIM process, the proton gradient served as a driving force to transport NH2OH(I). The electrodialysis (ED) process was used to efficiently and continuously provide proton gradient without introducing other ions, which coupled with PIM to separate HA. Under the optimum conditions, the separation factors of NH2OH(I)/Na(I) and NH2OH(I)/K(I) were 30.81 and 35.11; the purity of HA was 99.4%, indicating that the PIM-ED process can be used for high-purity preparation of HA.
Public Vitality-Driven Optimization of Urban Public Space Networks—A Case Study from Nanjing, China
Authors: Xu Ning , Zhang Xiao , Wang Pu
Published: January 2025

Spontaneous recreational activities in public spaces are a vital source of public vitality. Given the similarity between the walking patterns of recreational crowds in public spaces and the movement of electrons on a two-dimensional circuit surface, this study combines big data from various sources to create an “electrical conductivity surface” that attracts and aggregates recreational crowds. Using current flow simulation, we generate the path selection preferences of people as they move across public spaces. The results reveal an uneven distribution of public spaces in Nanjing’s main urban area, with high-vitality areas mostly concentrated in the urban center. The core demand for enhancing public vitality lies is improving connectivity between multiple spaces. Based on this, the public space plan for Nanjing’s main urban area emphasizes overall connectivity by aligning with the natural landscape, thus linking the city’s green and gray infrastructure. In this study, we have assessed current public space services and their development potential from a number of different angles, developing a digital approach for optimizing the urban layout. We aim to provide a human-centric, bottom-up perspective to complement the top-down city planning and management approach. This will enable urban planners to make informed decisions for creating and managing more vibrant cities.
Early Athletic Identity Formation and Development: Perceptions of Elite Gaelic Athletes
Authors: Geary Marion , Kitching Niamh , Campbell Mark , Houghton Frank
Published: January 2025

Background/Objectives: Athletic identity (AI) is an important part of an elite athlete’s self-concept and can positively impact sports performance, but over-emphasis can lead to potentially negative outcomes. Identity theory suggests that identity is shaped by individuals’ roles, group affiliations, self-perceptions, and important changes in personal circumstances. Athlete transitions are changes that occur in an athletes’ athletic and/or non-athletic circumstances, which can impact identity development. Using identity theory, this study aimed to explore the athletic transitions important in early AI formation and development in elite Gaelic athletes. Methods: Nine athletes were purposively sampled and participated in semi-structured interviews that were analysed using a six-step thematic analysis. Results: Findings indicate that the initiation, development, and mastery transitions in sport influence AI formation and align with the identity theory precepts of roles, groups, and persons in identity development. AI formation and development is individualised and shaped by perceived athlete competence, associated external validation, and the increased professionalism and personal commitment associated with higher levels of performance. Conclusion: We call for a greater emphasis to be placed on the development of multi-faceted identity profiles in elite Gaelic athletes.
Open Innovation and Entrepreneurship: A Review from the Perspective of Sustainable Business Models
Authors: Huang Jiayi , Zhou Peng
Published: January 2025

Open innovation serves as a critical pathway for aligning Sustainable Business Models (SBMs) with the dual imperatives of sustainability and the digital economy. This editorial review synthesizes insights from theoretical frameworks, particularly the Resource-Based View (RBV) and Transaction Cost Theory (TCT), integrated with the Technology-Organization-Environment (TOE) framework to explore the mechanisms driving open innovation. Our editorial review highlights the key dimensions influencing open innovation: technology (digital platforms, emerging technologies like AI, IoT, and blockchain), organization (stakeholder collaboration, governance mechanisms), and environment (regulatory frameworks, market dynamics, and industrial spillovers). This unified framework offers actionable insights for policymakers to foster enabling ecosystems and for business leaders to adopt open innovation strategies for resource optimization and governance improvement. The review concludes that the RBV-TCT-TOE framework provides a generalizable and robust tool for understanding and advancing open innovation across industries and regions, bridging theoretical and practical dimensions to address the challenges of sustainability and digital transformation.
Exploring the Driving Factors of Land Use Change and Spatial Distribution in Coastal Cities: A Case Study of Xiamen City
Authors: Zhang Tianhai , Foliente Greg , Xiao Jiangtao , Tang Lina
Published: January 2025

This study focuses on the coastal city of Xiamen, examining the factors and driving mechanisms influencing land use changes and spatial patterns. Spatial logistic regression and Statistical Package for the Social Sciences (SPSS) software were employed using grid data with a resolution of 100m to analyze the spatial relationships between six driving factors (such as elevation and slope) and five land use types within the study area. Regression models were established for each factor, and all Relative Operating Characteristic (ROC) tests were passed. Based on the results of the logistic regression analysis, land use changes and spatial distribution were simulated using the updated Conversion of Land Use and its Effects (CLUE) model so as to validate the driving mechanisms. The findings indicate that the six driving factors effectively explain the spatial patterns of land use in the study area. The distance to the coastline is the primary influencing factor in the evolution of spatial patterns, particularly impacting built-up land and farmland, while for forest land, slope is the main factor affecting the spatial distribution. The simulation and accuracy analysis revealed an overall simulation accuracy ranging from 73% to 90.1%, demonstrating that the selected driving factors have effective explanatory power for the spatial distribution of land use. Thus, this study’s results provide valuable insights into the complexity of land use changes and serve as a reference for relevant departments in land use management and planning.
Correction: Li et al. The Opening of High-Speed Railway and Coordinated Development of the Core–Periphery Urban Economy in China. Sustainability 2023, 15, 4677
Authors: Li Jiaqi , Elahi Ehsan , Peng Cheng , Wu Aimin , Cao Fengtong , Wang Jian , Abro Mohammad Ilyas , Khalid Zainab
Published: January 2025

The authors would like to make the following corrections about the published paper [...]
Sustainable Lightweight Concrete Designed with Modified Solidified Wastewater Sludge as Partial Replacement of Cement
Authors: Škondrić Marina , Radević Aleksandar , Savić Aleksandar , Naunović Zorana , Radovanović Željko , Svetozarević Snežana , Rajaković-Ognjanović Vladana
Published: January 2025

The requirement for high-quality drinking water and the treatment of wastewater prior to discharge into the environment results in the generation of sludge. As with any high-volume materials, beneficial reuse applications are being sought to promote sustainable environmental solutions. This research examined the possibilities of producing sustainable lightweight concrete using modified solidified wastewater sludge as a partial replacement of cement. Wastewater sludge was modified by the addition of aluminum oxide and magnesium silicate hydrate. The properties of the modified wastewater sludge were examined, as well as the influence of the partial cement replacement with the sludge in lightweight concrete. Besides testing the physical and mechanical properties of four mortar mixtures, an additional analysis of the willingness of final users to accept novel material containing wastewater sludge was addressed. The results obtained for the mortar samples indicate that 20% cement replacement is the upper limit for the modified sludge’s application. The lightweight concrete prepared with the modified sludge (in the amount of 20%) was tested in a hardened state. The water permeability was reduced by 33.3% with the addition of the modified sludge. Both tested concrete mixtures showed good frost resistance. The maximal measured reduction in the compressive strengths was 7.6%. Citizens’ perceptions and responses regarding the beneficial reuse of materials emphasize the importance of comprehensive education for their future acceptance.
Assessment of Socio-Economic and Environmental Impacts of Energy Efficiency Improvements in Multi-Apartment Buildings: Case Study of Lithuania
Authors: Balsiūnaitė Rimantė , Bobinaitė Viktorija , Konstantinavičiūtė Inga , Lekavičius Vidas
Published: January 2025

This research aims to assess the socio-economic and environmental impacts of the Lithuanian long-term renovation strategy, focusing on improvements in the energy performance of renovated multi-apartment buildings in the country. The methodology used in the study is centred on the CleanProd general equilibrium model, which is based on publicly available data from the FIGARO database and Eurostat’s non-financial transaction statistics. The four renovation financing scenarios analysed are represented in the model by changes in the demand for energy resources and construction and other transactions related to the renovation programme. To reflect the dynamic nature of the renovation programme, counterfactual equilibria are sought for each year of the renovation programme. The results revealed that renovation of multi-apartment buildings brings net benefits, including long-term increases in gross domestic products (GDPs) and employment, as well as a decrease in economy-wide greenhouse gas (GHG) emissions, and is aligned with the binding European Union’s energy efficiency target to reduce energy consumption at least by 11.7% in 2030 (in comparison to 2020). The Increase in Taxes on Products scenario is modelled as the most favourable scenario. It assures annual GDP growth by 0.37%, employment growth by 2170 jobs a year, including 606 jobs for young people, and an annual decrease in GHG emissions by 929–1043 ktCO2eq. It is found that the most considerable benefits are received during the renovation of medium-size buildings when construction demand increases by EUR 600,000–800,000 per year and natural gas and district heating demand are reduced by EUR 59,000–187,000 per year. Other scenarios demonstrating different building renovation and energy efficiency support practices, including Costless, Reallocation of Governmental Expenditure, and Governmental Loan, show relevant but slightly lower benefits.
A Chaotic Jerk Oscillator with Complete Control via Fractional Exponentiation and Its Experimental Analog Circuit Realization
Authors: Shen Menghui , Li Chunbiao , Cen Xiaoliang , Zhao Manyu , Xu Yuanxiao , Minati Ludovico
Published: January 2025

By introducing fractional exponentiation into a three-dimensional chaotic system, a jerk system with only six terms is designed. It has the property of total amplitude control, where a single non-bifurcation parameter can directly rescale all system variables without affecting the dynamics. It also features two-dimensional offset boosting, where a single parameter can realize direct offset boosting while another provides interlocked cross-dimensional offset boosting. Furthermore, this jerk system has a parameter-dominated symmetric attractor, which means that symmetric attractors appear successively as the parameter changes from positive to negative. Circuit experiments confirm the feasibility of analog fractional exponentiation using the 444 circuit and the complete control, including amplitude control and offset boosting, of the resulting system. The proposed circuit may facilitate applications of chaotic signal generators where signal versatility is important and exemplifies the generative potential of analog fractional exponentiation.
Acid-Base Equilibria for Tautomeric Heterocycles in the Gas-Phase: A Case of Uracil
Authors: Raczyńska Ewa Daniela
Published: January 2025

Prototropic conversion (prototropy) for heterocyclic nucleobases was already signaled by Watson and Crick about seventy years ago as one of the reasons for nucleic acids mutations. This isomeric phenomenon has been investigated for neutral derivatives by means of both experimental and theoretical procedures, and their favored tautomers discussed in numerous articles published in the last fifty years. Protonation/deprotonation reactions in the gas phase have also been studied using both quantum-chemical calculations and experimental techniques. Some thermochemical parameters of these processes have been documented. However, prototropy has not always been taken into account in protonation/deprotonation reactions. Most frequently, tautomeric heterocycles have been treated as simple polyfunctional compounds without possible intramolecular protontransfers. Taking into account the lack of data for the complete tautomeric mixtures, quantum-chemical investigations have been undertaken by us about twenty-five years ago for prototropic heterosystems. In this work, the pyrimidine base uracil (U) was chosen. It possesses two identical exo groups (=O/OH) at the 2- and 4-positions, two labile (tautomeric) protons, and five conjugated sites (N1, N3, C5, O7, and O8). Different types of isomerism, prototropy and OH-rotation, were considered for the neutral, protonated, and deprotonated forms. Using quantum-chemical methods, thermochemical stabilities of all possible tautomers-rotamers were examined in vacuo and the potential isomers selected. The selected isomeric mixtures for the neutral and ionic forms were applied for the determination of the thermochemical parameters in the four-step acid/base equilibria: B2− BH− BH2 BH3+ BH42+, where BH2 indicates U. For each step, the microscopic (kinetic) and macroscopic (thermodynamic) acid/base parameters were estimated, and sites of the proton gain and proton loss examined. The similarities and differences between the acid/base equilibria for uracil and other pyrimidine nucleobases were discussed.
Operational Risk Assessment of Commercial Banks’ Supply Chain Finance
Authors: Xie Wenying , He Juan , Huang Fuyou , Ren Jun
Published: January 2025

Supply chain finance (SCF) operations require extensive activities and a high level of information transparency, making them vulnerable to operational issues that pose significant risks of financial loss for commercial banks. Accurately assessing operational risks is crucial for ensuring market stability. This research aims to provide a reliable operational risk assessment tool for commercial banks’ SCF businesses and to deeply examine the features of operational risk events. To achieve these goals, the study explores the dependency structure of risk cells and proposes a quantitative measurement framework for operational risk in SCF. The loss distribution analysis (LDA) is improved to align with the marginal loss distribution of segmented operational risks at both high and low frequencies. A tailored copula function is developed to capture the dependency structure between various risk cells, and the Monte Carlo algorithm is utilized to compute operational risk values. An empirical investigation is conducted using SCF loss data from commercial banks, creating a comprehensive database documenting over 400 entries of SCF loss events from 2012 to 2022. This database is analyzed to identify behaviors, trends, frequencies, and the severity of loss events. The results indicate that fraud risk and compliance risk are the primary sources of operational risks in SCF. The proposed approach is validated through backtesting, revealing a value at risk of CNY 179.3 million and an expected shortfall of CNY 204.9 million at the 99.9% significance level. This study pioneers the measurement of SCF operational risk, offering a comprehensive view of operational risks in SCF and providing an effective risk management tool for financial institutions and policymakers.
Deep Learning Framework Using Spatial Attention Mechanisms for Adaptable Angle Estimation Across Diverse Array Configurations
Authors: Mylonakis Constantinos M. , Velanas Pantelis , Lazaridis Pavlos I. , Sarigiannidis Panagiotis , Goudos Sotirios K. , Zaharis Zaharias D.
Published: January 2025

Rapid advancement of wireless communication systems and the increasing need for accurate, real-time signal processing have driven innovations in direction-of-arrival (DoA) estimation techniques. This paper introduces a novel convolutional neural network (CNN) architecture that combines spatial attention mechanisms with a transfer learning framework to enhance both accuracy and versatility in DoA estimation. The model integrates spatial attention layers to dynamically prioritize signal regions with the highest information value, allowing it to isolate relevant signals and suppress interference in noisy or crowded signal environments. In addition, we utilize a transfer learning framework that enables the model to generalize across various antenna array configurations (i.e., planar, linear, and circular arrays) with minimal additional training. Extensive simulation results benchmark the proposed model against existing state-of-the-art methods for DoA estimation, achieving improved absolute error across diverse conditions. This hybrid approach not only enhances DoA estimation precision, but also significantly reduces retraining requirements when adapting to new array configurations, positioning it as a robust, scalable tool for next-generation wireless communication systems.
Sicurpest: A Prototype of a User-Friendly Tool for Preventive Risk Assessment of Pesticide Use in Agriculture
Authors: Rubino Federico Maria , Puri Daniele , Fargnoli Mario , Lombardi Mara , Mandić-Rajčević Stefan , Colosio Claudio
Published: January 2025

In recent years, there has been a significant increase in attention towards the use of pesticides, as evidenced by the introduction of regulations aimed at ensuring their safe and environmentally responsible application. Although this stricter legislative framework offers potential benefits, the challenges faced by farmers, particularly those in small-scale operations, in complying with occupational health and safety (OHS) requirements are considerable. To address this issue, a research project was promoted by the Italian Workers’ Compensation Authority (INAIL) aimed at developing a user-friendly software tool to support farmers in planning pesticide applications in safe conditions. This study summarizes the results of the research, which consisted of three main phases: the definition of the main parameters that characterize the farmers’ exposure based on the analysis of the literature; the development of a risk assessment model that integrates these determinants with data provided by producers for each authorized pesticide; and the development of software tool (called SICURPEST) for a preliminary risk assessment when using pesticides. This tool serves as a preliminary risk assessment method, offering a simplified model for practical use by farmers. Its initial verification was conducted through a case study and the results represent a step towards promoting safer pesticide practices, providing a solid basis for further validation.
The Tolerance Differences of Two Industrial Hemp Varieties Under Lead (Pb) Stress
Authors: Xu Yanping , Kumpeangkeaw Anuwat , An Xia , Chen Xuan , Zhang Yuan , Lv Pin , Zhang Qingying , Guo Rong , Ji Qingqing , Yang Ming
Published: January 2025

Industrial hemp is a crop with a high tolerance and accumulation of lead (Pb). Improving the Pb tolerance and accumulation capacity of industrial hemp is of great scientific and practical importance. This study utilized a pot with soil contaminated with Pb to investigate the differences in Pb tolerance between two industrial hemp varieties, Yunma1 (YM) and Shaanxi Industrial Hemp (SM), under Pb stress. The results indicated that Pb mainly accumulates in the roots of YM and SM (70–80%), with YM having a higher Pb accumulation than SM. It is worth nothing that under high Pb concentration conditions (5000 mg/kg), the Pb accumulation capacity of YM is twice that of SM. Accumulation characteristics of Pb in different plant tissues followed the pattern: roots > stems > leaves > fibers > seeds. In YM, approximately 70% of the absorbed Pb was fixed in the roots and 30% was transported to the above-ground parts. In contrast, SM transported more than 50% of absorbed Pb by roots to the above-ground areas, causing some degree of damage to stems and leaves. Even when Pb concentrations exceed 4000 mg/kg, YM exhibits strong tolerance (tolerance index greater than 90%), with normal growth and no signs of toxicity. However, SM showed a tolerance level of < 50% at high Pb concentrations, with significant heavy metal toxicity symptoms in the above-ground areas. These results provide important information for the remediation of Pb contaminated soils in mining areas.
Hadronic Molecules with Four Charm or Beauty Quarks
Authors: Liu Wen-Ying , Chen Hua-Xing
Published: January 2025

We apply extended local hidden-gauge formalism to study meson–meson interactions with the quark constituents ccc¯c¯, ccc¯b¯/c¯c¯cb, ccb¯b¯/c¯c¯bb, bbc¯b¯/b¯b¯cb, and bbb¯b¯, in which the exchanged mesons are the fully heavy vector mesons J/ψ, Bc* and Υ. We solve the coupled-channel Bethe–Salpeter equation to derive two poles in the bbc¯b¯ system and two poles in the ccc¯b¯ system. There are also four charge-conjugated poles in the b¯b¯cb and c¯c¯cb systems. In the bbc¯b¯ system, one pole corresponds to a sub-threshold bound state when the cutoff momentum is set to Λ>850 MeV. The other pole in this system corresponds to a sub-threshold bound state when Λ>1100 MeV. In the ccc¯b¯ system, the two poles correspond to sub-threshold bound states only when Λ>1550 MeV and Λ>2650 MeV. This makes them difficult to identify as deeply bound hadronic molecules. We propose investigating the two poles of the bbc¯b¯ system in the μ+μ−Bc− channel at the LHC.
The Influence of the Temperature on Effectiveness of Selected Disinfectants Against African Swine Fever Virus (ASFV)
Authors: Juszkiewicz Małgorzata , Walczak Marek , Woźniakowski Grzegorz , Pejsak Zygmunt , Podgórska Katarzyna
Published: January 2025

African swine fever (ASF) is one of the most economically significant diseases of pigs caused by African swine fever virus (ASFV). Due to the lack of effective and safe vaccines, one of the crucial measures to protect farms from the introduction of the ASFV is to apply a strict regime of biosecurity and disinfection. However, in field conditions, the activity of disinfectants may be influenced by temperature, resulting in reduced activity or biodegradation (i.e., freezing or evaporating). The aim of this study was to evaluate the effect of a wide range of temperatures on the virucidal activity of selected active substances commonly used against ASFV. Eight active substances were tested, namely: sodium hypochlorite (1.0%), glutaraldehyde (0.1%), potassium peroxysulfate (0.5%), caustic soda (1.0%), phenol (1.0%), acetic acid (3.0%), benzalkonium chloride (1.0%), and formaldehyde (0.4%). The virucidal activity of each compound was tested at different temperatures (21, −10, and −20 °C for 30 min) and compared to the initial virus titer under the same temperature conditions. Exposure to a range of temperatures did not significantly affect the virucidal efficacy of tested active substances against ASFV. Most of the evaluated substances had reduced virus titers ≥ 4 log10, regardless of the temperature. However, two of them (benzalkonium chloride and acetic acid) were sensitive to sub-zero temperatures, showing a lack of the required 4 log10 virus titer reduction. The conducted study showed that temperature could hamper the virucidal effect of selected substances (i.e., benzalkonium chloride and acetic acid), showing their moderate efficacy against ASFV −10 °C and −20 °C. The results suggest that extreme caution should be taken while applying these substances at sub-zero temperatures. The other substances had no significant sensitivity to the temperature range. Nevertheless, in the case of freezing the agent, insufficient penetration of the disinfected surface may occur, which may result in an ineffective disinfection process.
Immune Modulation Related to High-Dose Valacyclovir Administration for Primary Cytomegalovirus Infection in Pregnancy: An Insight into Virus Behavior and Maternal Serology
Authors: De Santis Marco , Tartaglia Silvio , Cerra Chiara , Visconti Daniela , Valentini Piero , Lanzone Antonio , Masini Lucia , Santangelo Rosaria
Published: January 2025

Cytomegalovirus (CMV) infection during pregnancy poses significant maternal and fetal health risks. Valacyclovir, an antiviral drug, has been explored as a therapeutic option for managing primary CMV infections in pregnant women. This study investigates the effects of valacyclovir therapy on immune response maturation against CMV, maternal antibody levels, and viral replication during treatment. We conducted a retrospective observational study involving pregnant women diagnosed with primary CMV infection and presenting in utero infection who received high-dose valacyclovir therapy (8 g/day). A group started the therapy at diagnosis, while another group started only after positive amniocentesis. Maternal antibody levels (IgM, IgG, and IgG avidity) and PCR for CMV testing (in blood, urine, and saliva) were measured longitudinally during the second and third trimesters. Our findings indicate that early valacyclovir therapy is related to lower avidity levels over time and a delay in reaching a high IgG avidity level (18.22 ± 1.21 weeks) compared to the patients who started Valacyclovir during the second trimester after positive amniocentesis (14.52 ± 1.64 weeks; p = 0.066). The therapy does not condition the overall concentration of maternal CMV-specific IgM and IgG. While high-dose VCV does not directly target the mechanism of IgG avidity maturation, it can interfere with this process by reducing the viral load and antigen presentation, influencing IgG avidity maturation. Further research is needed to elucidate the long-term implications of potential immunological modulation induced by Valacyclovir and to optimize early diagnosis and the right treatment protocol during pregnancy.
Practitioner perspectives on symptomatic faecal immunochemical testing: a qualitative interview study
Authors: Dobson Christina , Biran Adam , Rees Colin , Hamilton William , von Wagner Christian , Whelpton John , Sharp Linda
Published: January 2025

Background: Faecal Immunochemical Testing (FIT) is now core to the management of patients presenting in primary care with symptoms of possible colorectal cancer. Patients with a positive FIT (≥10μg Hb/g faeces) qualify for an urgent suspected cancer referral. FIT negative patients are typically managed in primary care or referred through routine pathways. Aim: To examine practitioners’ experiences of delivering symptomatic FIT, identifying perceived benefits, disbenefits and implementation issues, to inform potential future service improvements. Design and Setting: Qualitative interview study with primary and secondary care health professionals, from across the UK, involved in delivering symptomatic FIT pathways. Method: 30 semi-structured interviews with professionals from a range of specialties. An iterative topic guide informed interviews while allowing freedom to explore novel lines of inquiry. Pseudo-anonymised transcripts were coded and themes identified and developed. Results: Symptomatic FIT was seen to be beneficial for increasing confidence in clinical decision-making and enriching the pool of patients being definitively investigated for colorectal neoplasia. There were varying views on the impact of symptomatic FIT on workload with the burden of additional workload generally seen to be located in primary care. Concerns about current practice included over-use of FIT, burden of investigations in patients with false-positive results and diagnostic delays, for both cancer and benign disease. Uncertainties existed around management of patients with rectal bleeding, appropriate strategies for safety-netting, and the value of repeat FIT. Conclusion: Symptomatic FIT is largely seen as beneficial; however, health professionals would welcome further evidence and guidance around optimal application.
Nivel socioeconómico y hábitos de estudio en educandos universitarios del Altiplano peruano
Authors: Lipa Tudela Luzbeth , Mamani Yucra René , Geldrech Sanchez Patricia , Quilca Soto Yessica , Supo-Condori Felipe
Published: January 2025

Se llevó a cabo un estudio con el objetivo de determinar la relación entre el nivel socioeconómico y los hábitos de estudio. El método empleado fue bajo un enfoque cuantitativo de tipo correlacional. La población estuvo constituida por 60 estudiantes de la facultad de Educación y la muestra quedo conformada por 48 sujetos. Para la recolección de los datos se utilizó como técnica la encuesta y como instrumento dos cuestionarios: el Socioeconómico de Graffar y el inventario de Hábitos de Estudio CASM-85. Los resultados demuestran que, a nivel socioeconómico el 54% presenta un nivel inferior, el 40% tiene bajo superior y el 6% maneja el nivel marginal; en cuanto a los hábitos de estudio, el 52% obtiene una tendencia negativa, el 35% presenta un estudio negativo, el 6% conceptualiza al estudio como tendencia positiva, el 4% representa un estudio positivo y, finalmente, el 2% de estudiantes ve al estudio como algo muy positivo. En conclusión, la dinámica socioeconómica no resulta ser determinante frente a los hábitos de estudio en la educación superior
Planificación curricular, un modelo metodológico para su mejora
Authors: Neyra Símbala Luz Marina , Espejo Lázaro Juan Carlos , Carruitero Avila Nancy Aida , Llaury Acosta María Victoria
Published: January 2025

La planificación curricular es un proceso esencial del currículo para el logro de mejores aprendizajes. El objetivo del estudio fue elaborar un modelo metodológico con enfoque constructivista-sistémico que ayude a los docentes de primaria a planificar los programas curriculares. Estudio cuantitativo, de tipo explicativo, realizado con 40 docentes, con diseño preprueba – postprueba y grupo de control, se aplicó el modelo metodológico basado en responder a interrogantes: ¿Qué aprenderán? ¿Cuándo lo aprenderán? ¿Cómo lo aprenderán? ¿Qué, cómo y cuándo saber que han aprendido? y se utilizó como instrumentos: dos fichas de verificación de programas curriculares. Los resultados obtenidos evidencian mejoras significativas en los docentes del grupo experimental teniendo niveles: muy bueno y bueno, con un t de student (t=4,72 y t=4,28). En conclusión, la ejecución adecuada y coherente de los procedimientos del modelo ayuda a los docentes a elaborar sus programas curriculares en menos tiempo, con menor esfuerzo y mayor eficacia
Motivación laboral y bienestar psicológico en docentes peruanos
Authors: Huamán Mariscal Julia
Published: January 2025

El bienestar psicológico y la motivación laboral de los docentes en educación superior, son factores que inciden en la calidad de la enseñanza a nivel universitario para mejorar la calidad de la enseñanza. El objetivo del estudio fue relacionar ambas variables a través de una investigación de tipo correlacional. La muestra, estuvo compuesta por 144 docentes. Para recopilar la información de la variable bienestar psicológico se empleó la Escala de Ryff en versión de 39 ítems (conocido como SPWB39), distribuidos en seis dimensiones: autoaceptación, relaciones positivas, autonomía, dominio del entorno, propósito en la vida y crecimiento personal. Para la variable motivación laboral se usó la Escala McClelland: versión 30 ítems, distribuidos en tres dimensiones: afiliación, logro y poder. Se logró evidenciar una correlación positiva (r=0.9484) y significativa (p<0.05) entre la motivación laboral (X) y el Bienestar Psicológico (Y). Por lo cual, la motivación laboral puede contribuir al bienestar psicológico de las personas en su entorno laboral.
Residência pedagógica em ação: a vivência inicial de residentes de matemática / Pedagogical residency in action: the initial experience of mathematics residents
Authors: De Lima Luis Ricardo , Oliveira Eduarda de , Schmitz Tiago , Rosa Reinert Scheila Priscila , Selli Melz Elisângela Regina
Published: January 2025

O objetivo deste relato é apresentar as ações e as experiências dos licenciandos em Matemática do Instituto Federal Catarinense, câmpus Rio do Sul, durante o primeiro módulo do programa de Residência Pedagógica (RP). Para tanto, descreve-se os regulamentos normativos e os processos organizacionais do módulo I, como: cronograma temático de palestras e rodas de conversas com convidados especialistas, estudos documentais das escolas cedentes, levantamento bibliográfico e apresentações, teorias e tendências educacionais, procedimentos de preparação e execução de intervenções em sala de aula, produção e aplicação de oficinas e socialização de resultados. Além disso, o texto discorre sobre os desafios e superações de aulas remotas em meio à pandemia. O desenvolvimento das oficinas pedagógicas que ocorreram durante o módulo I, foram desafiadoras pois sendo de forma remota os residentes tiveram que explorar sua criatividade para poder desenvolver da melhor forma todas as atividades propostas. Não obstante, foi necessário ter sensibilidade para perceber cada aluno nesse novo momento de ensino e aprendizagem, em meio às tecnologias, mas também as realidades das famílias. Por fim, foi possível concluir que as oportunidades oferecidas pelo programa são significativamente positivas para todos os(as) envolvidos(as) e ímpares para formação docente, pela vivência de estar, mesmo de forma remota, em sala de aula participando desses momentos. Evidente que a teoria, neste momento, se fez como parte fundamental do processo mas, contudo, percebe-se que a prática também é de suma importância. Pois, é com a prática acompanhada pelos preceptores que percebemos o que é possível fazer e refletir com esses inovadores ambientes escolares.
Pengembangan Aplikasi Mobile Kuis Kosakata Text-to-Speech Bahasa Inggris dengan User-generated Content
Authors: Ridhoni Wahyu , Tri Asmara Linda , Romadoni Jiki
Published: January 2025

Penelitian ini bertujuan untuk mengembangkan aplikasi Mobile Kuis Kosakata Text-to-Speech Bahasa Inggris dengan fitur User-Generated Content yang memungkinkan pengguna menambah kosakata sesuai kebutuhan. Pengujian User Experience dilakukan menggunakan instruman UXD FLIP dengan tiga aspek: Mudah, Ramah, dan Indah. Hasil uji menunjukkan bahwa aspek Mudah memperoleh nilai 83,4, Aspek Ramah 82,4, dan aspek Indah 78,3. Secara keseluruhan, aplikasi ini memperoleh nilai akhir 81,4 yang tergolong sangat valid. Pengujian statistik menggunakan Wilcoxon Signed Rank Tes terhadap 107 partisipan menghasilkan nilai Z sebesar -8,79 Dengan p < 0,05, menunjukkan perbedaan signifikan antara nilai pre-test dan post-test. Dengan hasil ini, aplikasi dinyatakan efektif dan dapat digunakan dalam pembelajaran bahasa Inggris
AgroflorIF: sistema agroflorestal como construção do Bem Viver
Authors: Basconi Tatiane Cristina Fernandes , Tinós Thaís Minatel , Amo Gabriela Salvador de , Conde Daniele Cristina Chiconato , Stuqui Bruna , Palomo Vanessa de Souza
Published: January 2025

Este resumo integra um projeto de extensão, em desenvolvimento desde 2019, no Instituto Federal de Educação, Ciência e Tecnologia de São Paulo (IFSP), Campus Catanduva. Entendendo a Educação como campo de disputa, portanto, como dimensão política, o projeto AgroflorIF: sistema agroflorestal no âmbito escolar e comunitário tem por objetivo ser ferramenta na promoção de uma educação ambiental transformadora, que, somada a tantas outras experiências agroecológicas articuladas em rede, contribui com a educação em agroecologia. O projeto materializa-se em um sistema agroflorestal e tem exercido importante papel na articulação do tripé ensino, pesquisa e extensão, inclusive tendo influenciado projetos integradores e de pesquisa. Trata-se de um projeto singular na região recebendo visitas monitoradas de estudantes e de pessoas interessadas em orientação para implantação de SAFs em áreas verdes, evidenciando o potencial de projetos com foco na educação em agroecologia.
Проблемы развития агропродовольственного комплекса: региональный аспект
Authors: Гятов А.В. , Шарданов А.А. , Боготырева К.А.
Published: January 2025

Проблемы повышения самостоятельности регионов, роста региональных агропродовольственных рынков, обеспечения продовольствием местного населения становятся все более актуальными с каждым днем. В статье рассматривается агропродовольственный рынок КабардиноБалкарской республики, как ключевой фактор обеспечения продовольственной и экономической безопасности региона.
Реализация инновационных программ как фактор развития агропродовольственного комплекса региона
Authors: Мамбетов А.Х. , Шарданов А.А. , Блиева Э.К.
Published: January 2025

Устойчивое социальноэкономическое развитие Российской Федерации невозможно без обеспечения сбалансированного развития субъектов Российской Федерации. В статье рассматривается на примере экономики КабардиноБалкарской Республики реализация региональных инновационных программ и оцениваются эффекты и результаты от их применения
Современные подходы к учетно-аналитической работе по расчётам с персоналом, связанным с оплатой труда
Authors: Мельгуй А.Э. , Ковалева Н.Н. , Ермакова Л.В.
Published: January 2025

В статье анализируются современные тенденции организации учетноаналитической работы в бухгалтерских службах экономических субъектов по расчетам с персоналом, связанным с оплатой его трудовой деятельности. Рассматриваются наиболее применяемые в отечественной хозяйственной практике формы и виды оплаты труда, а также порядок их учёта. Проводится анализ удержаний, которые можно классифицировать на определенные категории. Акцентируется внимание на некоторые проблемы учётноаналитического обеспечения расчётов с сотрудниками по заработной плате. На участке учетноаналитической работы бухгалтерского учета экономического субъекта необходимы наиболее высококвалифицированные работники, имеющие высокую профессиональную подготовку и проходящие непрерывное профессиональное обучение посредством курсов повышения квалификации. Так как сфера бухгалтерского учета подлежит жесткому нормативному регулированию, которое постоянно совершенствуется и изменяется.

The article analyzes the current trends of accounting and analytical work in the accounting services of economic entities on the calculations with personnel related to the payment of his work. The most applicable forms and types of pay, as well as the procedure of their accounting, are considered. Retentions are analyzed, which can be categorized into specific categories. The emphasis is on some of the problems of accounting and analytical provision of payments with employees on salaries. The accounting and analysis of the economic entity requires the most highly qualified workers with high professional training and ongoing vocational training through refresher courses. Because the accounting sector is subject to strict regulatory regulation, which is constantly being improved and changed.
Оптимизация системы налогообложения в организации с помощью иностранного юридического лица
Authors: Пономарев Д.М.
Published: January 2025

Данная статья поднимает актуальные проблемы оптимизации налогообложения. Ключевая направленность оптимизации налогов заключается в уменьшении налогооблагаемой базы организации. В процессе планирования налоговой политики необходимо учитывать современные направления развития налогообложения и налогового контроля. Так же организации должны учитывать опыт партнеров или конкурентов, которые уже проиграли или выиграли споры с налоговыми инспекциями по аналогичным вопросам.

The intentional of optimization of taxes is a reduction of the tax obligations of the organization. In the process of tax policy planning it is necessary to take into account the current trends in taxation and tax control. Also, organizations should consider the experience of partners or competitors who have already lost or won disputes with tax authorities on similar issues.
Формирование информации о собственном капиталев системе управления акционерного общества
Authors: Бадрутдинова Д.И. , Снеткова Т.А.
Published: January 2025

В условиях рыночной экономики роль системы управления формированием и эффективным использованием собственного капитала бесспорно велика, поскольку собственный капитал является одним из важнейших источников средств для существования и развития любого хозяйствующего субъекта. Информация о собственном капитале организации является особенно полезной и важной для принятия управленческих решений не только со стороны внешних пользователей (потенциальных инвесторов, настоящих собственников, кредиторов, деловых партнеров, государственных органов), но и со стороны внутренних пользователей бухгалтерской отчетности, которыми являются управленцы всех уровней управления.

In a market economy, the role of the management system for the formation and effective use of equity is undoubtedly great, since equity is one of the most important sources of funds for the existence and development of any economic entity. Information about the equity of the organization is particularly useful and important for management decisions not only by external users (potential investors, real owners, creditors, business partners, government agencies), but also by internal users of financial statements, which are managers at all levels of management.
Аллитерация в эпосе «Манас».
Authors: Алишова М.К.
Published: January 2025

Эта статья посвящена аллитерации в эпосе Манас , ее типам и использованию в переводе. Древний век аллитерации свидетельствует о богатом наследии кыргызского народа. В кыргызском фольклоре аллитерация обогащена сказками, старинными сагами, народными песнями и особенно эпическим Манасом . Самый древний и замечательный памятник устного традиционного фольклора, который на многие годы превзошел наши дни. В Манасе отразились история, культура, традиции, борьба за мирную жизнь, борьбу за честь, за этническую идентичность и за национальное существование. Эпический Манас , шедевр мировой поэзии и энциклопедии кыргызской нации, содержит все поэтические краски, приложения и жанры. Специфическими особенностями рифм Манаса являются исключительно развитая аллитерация, преимущественно первичная или анафорическая аллитерация.

This article deals with alliteration in epic Manas, its types and usage in translation.The ancient age of alliteration witnesses a rich heritage of the Kyrgyz nation. In Kyrgyz folklore alliteration is enriched in fairytales, old sagas, folk songs and especially in epic Manas. The most ancient and remarkable monument of oral traditional folklore, that surpassed many centuries to our present day. In Manas was reflected the history, culture, traditions, struggle for peaceful life, fight for honor, for ethnic identity and for national existence. A masterpiece of world poetry and encyclopedia of the Kyrgyz nation, epic Manas contains all poetic colors, applications and genres. Specific peculiarities of Manas rhymes exceptionally developed alliteration, mainly primary or anaphoric alliteration.