bluuebunny/crossref_metadata_2025 huggingface dataset:
Overview of Some Biochemical Parameters in Parkinson’s Disease
Authors: Tahiroglu Veysel , Gulcin Ilhami
Published: October 2024

Parkinson disease is a neurodegenerative disease that affects dopaminergic neurons in the substantia nigra. Parkinson’s disease is a disease that occurs with unwanted and uncontrolled movements, causing balance and coordination difficulties, resulting in tremor paralysis. Due to symptoms such as tremors, Parkinson disease significantly affects a person’s quality of life and can worsen if left untreated. In this section, the relationship between important biochemical parameters such as dopamine, insulin resistance, vitamin D, glycemic index, cholesterol, proteins and minerals, which have very important roles in the prognosis and treatment process of Parkinson, and Parkinson’s is evaluated. We believe that clinicians can manage the disease process more efficiently and effectively by taking into account the points expressed in this section in every process of Parkinson disease.
Radiologic Imaging of Scalp Lesions
Authors: Alver Kadir Han
Published: October 2024

Scalp lesions present significant diagnostic challenges due to their similar appearances, making accurate radiological assessment crucial in lowering mortality and morbidity rates.

Understanding the scalp's anatomy, which includes five distinct layers-skin, dense connective tissue, epicranial aponeurosis, loose connective tissue, and pericranium-enables precise lesion localization. The vast majority of scalp abnormalities (93–98%) are benign, with trichilemmal cysts being the most common, followed by epidermal and dermal cysts, lipomas, nevi, and sebaceous cysts. Although less frequent, malignant scalp tumors such as squamous cell carcinoma, basal cell carcinoma, lymphoma, metastases and malignant melanoma also occur and pose significant health risks.

Radiological imaging, particularly CT and MRI, plays a vital role in differentiating between benign and malignant lesions. Some characteristic imaging features of specific benign lesions, such as calcifications in trichilemmal cysts, fat density in lipomas, diffusion restriction in epidermoid cysts, and the typical locations of dermoid cysts with well-defined, non-invasive imaging features, aid radiologists in accurate diagnosis. On the contrary, although an accurate diagnosis of malignant tumors cannot be reached by radiological imaging alone, aggressive characteristics like bone erosion, destruction, and infiltration into surrounding tissues should predominantly raise suspicion of malignancy. Proper radiological evaluation and familiarity with the imaging features of these lesions are essential for accurate diagnosis and effective treatment planning, whether surgical or nonsurgical.
Imaging Findings in Benign and Malignant Small Bowel Tumors
Authors: Batur Abdussamet
Published: October 2024

GSmall bowel tumors are a rare medical occurrence, constituting only about 5% of all gastrointestinal tract tumors. Given the rarity, diagnosing these tumors presents distinct challenges. Benign small bowel tumors are noncancerous growths that do not spread to other parts of the body. They typically grow slowly, providing ample time for detection and treatment before causing any severe complications. Common benign tumors include adenomas, lipomas, leiomyomas, and GISTs (Gastrointestinal Stromal Tumors). These usually present symptoms like abdominal pain, bleeding, or obstruction; however, they might remain asymptomatic in some cases. Unlike benign lesions malignant tumors such as adenocarcinoma commonly present as irregular wall thickening with marked contrast enhancement reflecting their hypervascular nature along with encasement/invasion into adjacent structures and enlarged regional lymph nodes. Imaging methods are at the forefront in the diagnosis, staging and post-treatment follow-up of small bowel tumors. Ultrasonography, computed tomography and magnetic resonance imaging should be used as complementary radiological methods depending on the patient and/or disease status.
Radiological Findings of Cervical Cancer
Authors: Ozkacmaz Sercan
Published: October 2024

Cervical cancer is one of commonest gynecological cancers worldwide in which early diagnosis is very essential. For also detecting the the lesion and the staging the disease, radiological imaging modalities especially MRI are very useful. Lesions’ size, distance between internal cervical os and the edge of the lesion, invasion of parametrium, involvement of vagina, hydronephrosis, pelvic lateral side-wall invasion, rectum and bladder involvement , pelvic and/or para-aortic lymph node involvement are the major conditions must be evaluated on radiological examinations which change the grade and also the treatment options of the disease.
Pediatric Bone Tumors
Authors: Sara Halil Ibrahim , Durmaz Mehmet Sedat
Published: October 2024

Primary bone tumors are predominantly observed in the pediatric age group. Among benign bone tumors, osteochondroma is the most common, while osteosarcoma is the most frequent among malignant tumors. Important radiological criteria have been established to distinguish between benign and malignant tumors. Critical findings to consider include the patient’s age, the localization of the lesion, the morphological characteristics of the lesion, and the presence and type of periosteal reaction. By evaluating these findings, the differential diagnosis list can often be significantly narrowed. However, the primary expectation from radiology is not a specific diagnosis but rather an assessment of whether the lesion is malignant or benign. Radiography plays a crucial role in this distinction by highlighting important features such as periosteal reaction and the zone of transition. The radiography-based Lodwick classification, which evaluates the transition zone and margin characteristics of the bone lesion, is an important classification for indicating the aggressiveness of the lesion.
Interventional Radiological Treatments in Lung Cancer
Authors: Ozgokce Mesut
Published: October 2024

Lung cancer (LC) is the leading cause of cancer-related deaths globally, with about 1.76 million deaths in 2018. Smoking is the main risk factor, along with genetic predisposition and asbestos exposure. Primary LC starts in the lung tissue, while secondary LC spreads from other body parts to the lungs. LC is often classified into small cell and non-small cell types, which affects treatment plans. For non-small cell LC, surgical removal is the first option. Advanced cases might be treated with chemotherapy, radiotherapy, or combinations, but complete remission is rare. Minimally invasive treatments like microwave ablation (MWA), radiofrequency ablation (RFA), and cryoablation are used for local tumor control, especially in patients who can't undergo surgery. These methods help preserve lung function and improve quality of life. New techniques like Cyber-knife and Gamma knife are also emerging as alternatives to traditional ablation methods.
Interventional Radiological Treatments for Breast Lesions
Authors: Yuksek Mehmet
Published: October 2024

Breast tumors mainly include cancer and fibroadenomas. Treatment of these lesions has evolved towards the use of less invasive or minimally invasive techniques. Minimally invasive treatments destroy focal groups of cells using a non-surgical method. It requires less anesthesia, provides better cosmetic results due to minimal scarring, and provides earlier recovery. These techniques include cryoablation, radiofrequency ablation, microwave ablation, high-intensity focused US, laser therapy, vacuum-assisted excision, and irreversible electroporation. Each method involves the use of different mechanisms and applications require special considerations.
Brain Health and Nano Medicine
Authors: Tarhan Tuba
Published: October 2024

The most complex organ in our body is the brain. It also plays a significant role in regulating behavioural, emotional, and cognitive activities. The brain is the target of many ailments, from cancer to neurodegenerative diseases and injuries. Brain diseases refer to a broad group of disease conditions that affect the brain, such as dysfunctions, infections, tumours, injuries, and neurological disorders. In last years, nanotechnology has appeared as an important technique used to obtain materials with desired properties by changing and operating different items at the molecular level. With this feature, nanotechnology has proven to be useful in the diagnosis and medication of brain diseases and disorders by facilitating the distribution of drugs and increasing drug effectiveness. Brain diseases continue to be an important health, economic, and social burden due to high failure rates in transferring therapeutic drugs to the clinic. This chapter discusses the use of various nanoparticles in the diagnosis and treatment of brain diseases, including neurodegenerative disorders, brain tumours, and stroke. There are many promising publications in the literature studying different nanotherapeutics. However, further research on their toxicity and bioaccumulation in clinical settings is required to improve the application of nanotherapeutics in the brain. Thus, the potential of nanomaterials in the treatment of brain diseases and disorders is increased.
SARS-COV-2 and Brain Disease
Authors: Demir Fidel
Published: October 2024

Severe acute respiratory distress syndrome coronavirus 2 (SARS-CoV-2) primarily affects the lungs and causes respiratory distress, but also affects all other tissues, especially the brain and heart. COVID-19 has caused devastation, maiming and killing millions of people worldwide.

It is crucial to elucidate the factors involved in the development of this pandemic to prevent the emergence of similar pandemics in the coming years. Analysing the transmission routes, mechanism of action, treatment approaches and prognostic factors of SARS-CoV-2 is imperative for the future of humanity. Patients may experience neurological symptoms such as anosmia, wetusia, encephalopathy, meningitis and cerebral vascular events. Almost every symptom related to the nervous system can be seen in SARS-CoV-2 patients. In this article, I aimed to explain the neurological effects of SARS-CoV-2 in the light of the literature.
Oxytocin
Authors: Batu Ozlem
Published: October 2024

Oxytocin is a peptide hormone secreted from the posterior pituitary. Its best-known function is to increase milk secretion in breastfeeding women. It can be used pharmacologically to induce uterine contractions and sustain labour. However, it is thought that its contribution to birth is minimal at physiologically normal blood levels. This hormone, which acts as a neurotransmitter in the central nervous system, is also effective in regulating blood circulation. It balances the mood and is important in regulating behaviour in different emotional states. It helps to experience positive emotions. It has anti-inflammatory properties and this feature also increases the healing speed of wounds on the body. It reduces stress by lowering cortisol levels. It increases the pain threshold. It enables socialisation and prevents falling into an introverted mood. It increases sexual arousal and it makes it easier to empathize. Oxytocin is no longer the simple "love hormone" and, like many other hormones, has complex interactions with human health and behaviour. Although good progress has been made, much more research is needed to understand the effects of oxytocin fully.
What Is Immunotherapy and History of Immunotherapy in Cancers
Authors: Ayyildiz Orhan , Hekimoglu Yusuf
Published: October 2024

Immunotherapy, a transformative cancer treatment, harnesses the immune system’s inherent ability to combat neoplastic cells. Ancient medicine hinted at immunological principles, recognizing natural disease resistance and the body’s defensive capabilities. Over time, the understanding of the immune system evolved, with key contributions from early thinkers like Ibn Sina and later scientific pioneers like Ilya Mechnikov.

The immune system, comprising innate and adaptive components, is vital in defending against pathogens and regulating cell proliferation, including cancerous cells. The concept of immune surveillance highlights the immune system’s role in preventing cancer development.

Modern immunotherapy includes several approaches: monoclonal antibodies target specific proteins on cancer cells to mark them for destruction; cancer vaccines prevent virus-related cancers like HPV and hepatitis B; adoptive cell therapy, including CAR T-cell and TIL therapies, enhances patients’ immune cells to fight cancer; checkpoint inhibitors block proteins that allow cancer cells to evade the immune response; and oncolytic virotherapy uses engineered viruses to destroy cancer cells and stimulate the immune response.

These therapies, based on profound immunological insights, represent a significant advancement in oncology, offering new hope for patients by leveraging the immune system’s power to combat cancer.
Immunotherapy in Gynecologic (Ovary, Endometrium and Servics) Cancer
Authors: Kitapli Sait , Alkan Ali
Published: October 2024

Immunotherapy has shown remarkable success in treating various solid malignancies, but its application in gynecologic cancers is an evolving field. This paper provides a comprehensive overview of immunotherapy’s role in managing ovarian, endometrial, and cervical cancers. It delves into the mechanisms of immune checkpoint inhibitors, focusing on the PD-1 and CTLA-4 pathways, and their impact on tumor suppression. The review highlights the challenges posed by tumor immunoediting, where cancer cells evade immune responses. It emphasizes the significance of molecular phenotyping, particularly MMR deficiency and PD-L1 expression, in predicting treatment response. There are promising results from clinical trials investigating immune checkpoint inhibitors, both as single agents and in combination with other therapies, offering potential avenues for improving outcomes in gynecologic cancer treatment.
Types of Immunotherapy, Mechanism of Action and Side Effects
Authors: Sahip Yesiralioglu Birsen , Ertop Sehmus , Aslaner Ak Muzeyyen , Ayag Hatice
Published: October 2024

Immunotherapy has emerged as a ground breaking approach in the treatment of various cancers and autoimmune diseases, utilizing the body’s immune system to combat disease. This article reviews the mechanisms of action of different types of immunotherapy, including checkpoint inhibitors, monoclonal antibodies, and adaptive cell transfer. Checkpoint inhibitors such as PD-1/PD-L1 and CTLA-4 blockers enhance immune responses by releasing brakes on T cells, thereby promoting anti-tumor immunity. Monoclonal antibodies target specific antigens on cancer cells or immune cells, facilitating targeted destruction. Adaptive cell transfer involves modifying and re-infusing patient-derived immune cells to enhance their tumor-fighting capabilities. Despite their promise, immunotherapies can elicit immune-related adverse events ranging from mild to severe, affecting various organ systems. Common side effects include fatigue, rash, and gastrointestinal disturbances, while severe reactions may involve pneumonitis, colitis, or endocrinopathies. Understanding these mechanisms and side effects is crucial for optimizing patient care and expanding the therapeutic potential of immunotherapy.
Production Techniques of Nursery Plants in Diospyros Species
Authors: Yilmaz Nese , Gundogdu Mehmet Ali , Basaran Tuba , Gur Engin , Seker Murat
Published: October 2024

Persimmon (Diospyros kaki L.) is one of the subtropical fruit species with worldwide commercial production. In our country, its importance has been increasing day by day in recent years by both producers and consumers. Persimmon is a species with fewer problems in terms of resistance to environmental conditions, diseases and pests compared to many other fruit species. Persimmon, which is a soft-seeded fruit, is remarkable with its species-specific colours (yellow, orange, red) and shapes. Persimmon seedlings are propagated by generative and vegetative methods. The generative propagation method is mainly used in rootstock production. Clonal rootstocks, important in many fruit species, are not yet sufficiently used in persimmon. The rootstocks commonly used in our country are Diospyros kaki L. and Diospyros lotus L. species. Graft propagation, one of the vegetative propagation techniques, is widely used in the sapling production of persimmons. Not only chip buddings and T-buddings methods are commonly used in the budding propagation method, but also Cleft grafts and Whip grafts methods are preferred among grafting propagation methods. Persimmon orchard establishment is usually done with grafted saplings.
Afforestation As a Keystone in Sustainable Livestock
Authors: Karaman Kardelen
Published: October 2024

The world population is increasing every year and is expected to reach 9.7 billion by 2050. Therefore, the demand for efficient practices in food production systems and pressure on ecosystems is increasing. In addition, traditional animal husbandry practices exacerbate the effects of climate stress due to intensive land use and greenhouse gas emissions associated with animal husbandry. At this point, sustainability efforts are gaining importance, and these practices are characterized by the reforestation of the cattle industry, raising animals in agroforestry, increasing biodiversity along afforestation, and ensuring animal welfare. In addition, afforestation fulfills natural forage needs, serves water management and soil conservation, and reduces climate disruption through carbon sequestration. This study’s main objective is to assess afforestation’s contribution to sustainability, greenhouse gas mitigation, and socio-economic development.
Peritonsillar Abscess
Authors: Yasar Murat
Published: October 2024

Peritonsillar abscessis defined as the accumulation of purulent secretion in a potential area containing loose connective tissue between the palatine tonsil fibrous capsule and the pharyngeal superior constrictor muscle. It is usually encountered as a complication of streptococcal tonsillitis and pharyngitis. Peritonsillar abscesses have the most common deep neck infection in young adults. In peritonsillar abscess, early diagnosis and prompt initiation of treatment are critical to avoid potential complications. The treatment of peritonsillar abscesses includes abscess drainage, antibiotic treatment, hydration, and supportive treatment for pain control.
Fungal Rhinosinusitis
Authors: Kars Ayhan
Published: October 2024

recent years, diseases caused by fungi in the nose and sinuses have been increasing exponentially. Therefore, fungi are very important for otorhinolaryngologists and have been the subject of many discussions in the literature. The effect of fungi in the upper respiratory tract is not limited to fungal sinusitis. Since fungal sinus disease has a wide spectrum, it is interesting and difficult to understand and manage the disease process. It is very important to differentiate between the variants of fungal sinusitis and to recognise aggressive and fulminant disease. Early diagnosis is the key to successful management of the disease and clinicians often fail in this regard. Further research is needed to understand the immunopathogenesis, risk factors, geographical and occupational predisposing factors and to improve diagnostic methods.
Gamification and Mobile Apps for Rehabilitation
Authors: Yildiz Abdurrahim
Published: October 2024

The integration of gamification and mobile apps in rehabilitation offers a promising approach to enhance patient engagement and improve outcomes in physical therapy. Gamification, which involves incorporating game design elements into non-game contexts, has been shown to motivate patients by making rehabilitation exercises more engaging and enjoyable. Techniques such as immersive games, point systems, and personalized progress tracking can help reduce hospital stays and encourage self-management. Mobile apps further complement these efforts by providing convenient, flexible, and interactive platforms for delivering tailored home exercise programs, monitoring patient adherence, and offering educational resources. These digital tools not only support patients in their rehabilitation journey but also facilitate remote communication and monitoring by healthcare providers, ultimately contributing to more effective and efficient rehabilitation processes.
Proton Therapy: Present State and Future Prospects
Authors: Dirican Bahar
Published: October 2024

The use of high-energy protons for radiation therapy was first proposed by Wilson in 1946. Then, at five major centers, Berkeley (United States). Dubna (Russia), Uppsala (Sweden), Harward (United States) and Moscow (Russia), between 1950 and 1960 the use of proton therapy followed. In the beginning progress was slow: 1) Because proton dosimetry and imaging techniques for tumor localization were not well developed 2) Because the accelerators used to produce the proton beams were designed as experimental facilities rather than as clinical machines. More recently, significant growth has occurred in the number of accelerators used for proton therapy. The number of centers has significantly increased over the past decade and protons are now used with more routine in multiple disease sites worldwide.
Perception of Climate Change and Social Confidence
Authors: Sevinc Gonul , Sevinc Mehmet Resit
Published: October 2024

Efforts to deal with climate change and adaptation are currently on the agenda of many countries. Research and academic studies generally focus on two different perceptions of the emergence of climate change. The first is that climate change occurs as a natural process. The second is the perception that human activities, directly or indirectly, trigger and bring about climate change. In this study, the perception towards climate change and the level of social confidence towards climate change in Şanlıurfa province were investigated. According to the research findings, participants generally think that climate change exists. According to the participants, although climate change is a natural process, human activities have a greater impact on the occurrence of climate change. Participants who believe that climate change exists are generally male, single, urban residents, under the age of 28, with a high level of education, fixed and average/high household income. The same participants do not believe very much that the occurrence of climate change is a natural process. These participants attribute the emergence of climate change to human activities. Participants think that the measures taken by society, policy makers and practitioners against climate change risks are not sufficient. Especially the confidence levels of the participants who are male, single, living in the city, under the age of 28 and have a high level of education are quite low.
Environmental and Economic Impacts of Tillage Practices in the Context of Climate Change
Authors: Gursoy Songul , Akin Songul
Published: October 2024

Climate changes, such as the effects of soil tillage practices on climate change, have a significant impact on the selection of soil tillage practices. Weather and climate significantly influence the performance of tillage tool and machinery, also the efficiency of the applied soil tillage method. For example, climate properties such as in temperature, precipitation, and frost timing are considered when applied soil tillage systems because they significantly affect soil properties such as moisture, strength, temperature. Similarly, tillage practices have significant effect on climate change due to their profound influence on the physical properties of soil and the greenhouse gas balance. This chapter informs about how climate properties affects soil tillage practices as well as environmental and economic impacts of soil tillage practices. It consists of three section. The first section presents the main tillage systems, their applications, their advantages and limitations. The second section discusses the effects of tillage practices on soil, environment, crop, energy and economy such as soil properties, crop productivity, and global greenhouse gas, fuel consumption and carbon emissions which are pivotal factors in climate change. Third section reviews the effects of soil properties such as moisture, temperature and strength changed due to climate change (temperature, precipitation, and moisture regime changes etc.) on the efficiency of soil tillage practices.
Economic Importance of Maintenance Procedures in Pistachio Cultivation Under Climate Change Effects
Authors: Kilic Ahmet , Kuzucu Meryem
Published: October 2024

Climate change has significant implications for pistachio cultivation, particularly in regions like Gaziantep, Turkey. In this context, the economic importance of maintenance practices in pistachio cultivation becomes paramount. As temperatures rise and rainfall patterns become more erratic, pistachio orchards are subjected to increased stress, affecting both yield and quality. Proper maintenance practices, including irrigation management, pest and disease control, pruning, and soil management, play a crucial role in mitigating the adverse effects of climate change on pistachio production. Effective maintenance helps ensure optimal growth conditions for pistachio trees, leading to improved yields and product quality. Moreover, investing in maintenance practices can enhance the resilience of pistachio orchards to climate change, thereby safeguarding the economic viability of pistachio cultivation in Gaziantep and similar regions.
The Impact of Climate Change on the Sustainability of Safe Food
Authors: Ucan Turkmen Filiz , Sarigullu Onalan Fatma
Published: October 2024

Climate change, or global warming, is the result of rising temperatures caused by human activities such as the burning of fossil fuels and deforestation. Greenhouse gases, particularly carbon dioxide (CO2), trap the sun’s heat, leading to rising temperatures, changes in rainfall patterns, rising sea levels and melting glaciers. These changes have a significant impact on agricultural production, affecting the quality and quantity of food. Fluctuations in temperature, precipitation and soil moisture affect plant physiology, threatening food security and sustainability. This study highlights the importance of water and soil in food production and the need for sustainable agricultural practices and technologies. Implementing effective policies is essential to produce safe food, protect natural resources and mitigate the adverse effects of climate change. Ensuring a safe and sustainable agricultural system is essential to meet the food needs of a growing population and to maintain the health of the environment under changing climatic conditions.
Drought Stress Due to Climate Change in Plants and Nanoparticle Interactions
Authors: Ozkaya Rukiye , Gozel Hatice , Cetinkaya Hakan
Published: October 2024

Climate change directly affects agriculture and crop production all over the world. Global warming associated with climatic changes leads to a decrease in water resources and causes plants to live under stress conditions. Stress factors negatively affect crop production and increase yield losses. Drought stress is one of the most common abiotic stresses affecting growth and yield and affects many physiological, biochemical and molecular systems in plants. The areas of use of nanomaterials are increasing day by day. The use of nanomaterials in agriculture is seen as an important measure that can be taken against climate change. Nanoparticles are expected to improve the plant’s tolerance level to abiotic stress conditions, increase yield and quality in plants and thus provide new opportunities for the future of agriculture by reducing the impact of factors limiting plant production.
The Surgical Procedures in Pulmoner Cystic Hydatic in Children
Authors: Arslan Serkan , Basuguy Erol
Published: October 2024

This text explains the importance of the concept of "Being Me" in the family and what needs to be done about it. "Being me" is possible when the individual knows himself, is spiritually strong, determines his priorities, knows and fulfills his limits and responsibilities, and is also aware of the psychological wounds he has experienced in the past. This process begins with the individual’s increasing deep awareness of self-knowledge. The process of self-knowledge enables the individual to explore his inner world and understand emotional states. “Being me” requires being spiritually strong. Spiritually strong people manage their emotions, thoughts and behaviors in a way that provides them success in life. Determining priorities means understanding what the individual values in life and acting accordingly. Likewise, knowing responsibilities and boundaries allows for a healthy balance in social relationships and maintaining the necessary space for personal growth. Recognizing wounds means recognizing past traumas and taking steps towards the healing process. It refers to the individual’s selfishness of prioritizing his own needs in the process of "being me" as "not being able to break away from me". On the contrary, it refers to situations such as being unable to protect one’s own freedom and personal identity and creating one’s own happiness through the happiness and preferences of one’s partner, as "getting lost in you". In this context, the process of "Being Me" is an important journey for the individual to discover himself and become spiritually stronger and mature. When spouses who have completed this process come together, a family that is happy, healthy and knows what it wants is formed.
Historical and Chemical Examination of Alcohol
Authors: Uysal Cem
Published: October 2024

Patients with idiopathic pulmonary fibrosis contemplating pregnancy should receive comprehensive pre-pregnancy counseling, including discussions about the potential risks of pregnancy on disease progression and maternal health. Collaborative care involving obstetricians, pulmonologists, and maternal-fetal medicine specialists is essential to optimize maternal and fetal outcomes while minimizing risks to both. Careful consideration should be given to medication selection and dosing during pregnancy, with a focus on minimizing fetal exposure to teratogenic or harmful agents while maintaining maternal disease stability and symptom control. Close monitoring of maternal lung function, symptoms, and pregnancy complications is necessary throughout gestation, with regular assessments to detect any signs of disease progression or exacerbations.

Elderly patients with idiopathic pulmonary fibrosis. may present with age-related changes in lung function, comorbidities, and functional status, necessitating individualized management approaches. Comprehensive geriatric assessment, including evaluation of functional status, cognitive function, nutritional status, and frailty, is valuable in identifying and addressing age-related vulnerabilities and optimizing care for elderly patients with idiopathic pulmonary fibrosis.nTreatment decisions in elderly patients should balance the potential benefits and risks of pharmacological interventions, taking into account age-related pharmacokinetic and pharmacodynamic changes, comorbidities, polypharmacy, and frailty.
Psychiatric Evaluation of Alcohol Abuse in Children and Adolescents
Authors: Dogac Tugba
Published: October 2024

Alcohol use in adolescents is influenced by various hereditary, environmental, social, and psychological factors. This period is critical for brain development, with changes in the reward system leading to increased novelty-seeking and risk-taking behaviors. Early initiation of alcohol use can lead to long-term consequences, including addiction, comorbid psychiatric disorders, academic problems, and social issues. Risk factors include a family history of substance use, male gender, traumatic experiences, and weak parental control. Despite lower substance use rates compared to Europe, alcohol use in Turkey is rising. Effective interventions include early prevention, psychosocial treatments, and complementary therapies like music and animal-assisted therapy.
Nutrition in the Prevention and Treatment of Endometriosis
Authors: Balkan Nazenin
Published: October 2024

Endometriosis is a complex and often debilitating gynecological disorder characterized by the presence of endometrial-like tissue outside the uterus. While the exact cause of endometriosis remains unclear, emerging research suggests that dietary factors may play a significant role in both its development and management.Endometriosis involves a complex, chronic inflammatory process that coincides with the spread of endometriotic lesions into the peritoneum, characterized by proliferation, vascularization, and peritoneal invasion. As a result, there is considerable current interest and ongoing research into the potential for creating an anti-inflammatory response through appropriate nutrition, and understanding how this nutritional support may impact endometriosis.
Marriage Periods
Authors: Aydin Inci
Published: October 2024

This chapter deals with marriage processes and the emotional and psychological states experienced by couples during these processes. Love and affection form the basis of relationships, and the dating period is the process of couples getting to know each other and taking the relationship to marriage. According to Alan Lee’s "Colors of Love" theory, there are three basic forms of love: passionate love (eros), playful love (ludus) and friendly love. These three styles of love form the basis of other love styles. Additionally, attachment styles also affect relationship dynamics; such as secure attachment, preoccupied attachment, dismissive attachment and fearful attachment. The engagement process is a stage where the marriage proposal is accepted and families are involved, where couples have the opportunity to get to know each other better. The engagement process is a larger and more crowded event and is a period in which families and relatives recognize the relationship. For a healthy relationship and marriage, it is important for couples to know each other and achieve emotional and logical harmony. Secure attachment and empathy in the premarital period strengthens the relationship. When couples show love, respect and value to each other, their relationships become healthier and more permanent. This document aims to help couples understand the challenges they may face on the road to marriage and how they can overcome these challenges.
Family and Sexuality
Authors: Dursun Recep
Published: October 2024

In this section, where the concepts are defined, the importance of sexuality in ensuring family integrity is explained. Sexuality is an important and integral part of human life, as well as one of the basic elements that determine the quality of healthy life in our family life. Sexuality is closely related to mental health, with many aspects affecting our physical and emotional health. While discussing the definitions and functions of marriage, many scientists have combined marriage and sexuality in the same definition.

The basis of marriage lies in meeting and satisfying the basic needs of men and women. ""Sexual instinct is an interest that biologically ensures the continuation of the species, and socially it is a tendency that directs one person to another."" One of the basic ""biological"" functions of marriage is to ""satisfy the sexual instinct"", where the partners meet each other’s desires in harmony and the sexual instinct is satisfied in a legitimate way. As a result, the need to ""have children, raise them and produce their own generations"" is also met. Individuals’ needs for each other gain a certain meaning when the personalities in the family complement each other. The function of the family that ensures the continuation of the generation began with the existence of humans on earth and will continue as long as humanity exists.
O LUGAR QUE AS CRIANÇAS OCUPAM NAS PESQUISAS: UMA REVISÃO SISTEMÁTICA
Authors: Cervo Michele da Rocha
Published: October 2024

O presente estudo teve como proposta realizar uma revisão bibliográfica sistemática sobre a temática pesquisa com crianças. Dessa forma, a pesquisa foi realizada nas bases de dados LILACS, SCIELO e portal CAPES. A busca partiu dos seguintes descritores: pesquisa, criança, infância, metodologia e investigação. Foram selecionados apenas os artigos publicados entre 2003 e 2013, independentemente da área em que se concentram. A leitura dos materiais selecionados apontam para um movimento atual de considerar as crianças como atores sociais, apontando a necessidade de ouvi-las para que sua experiência auxilie na recondução de processos instituídos.
CONTRIBUIÇÕES DO PSICÓLOGO ESCOLAR NA EDUCAÇÃO INFANTIL
Authors: Caetano Roberta HURIN MELETTI , Silva Weslley Kozlik
Published: October 2024

O presente trabalho é uma revisão bibliográfica com análise qualitativa a fim de verificar o que tem sido publicado a respeito da atuação do psicólogo na educação infantil no Brasil de 2000 a 2014. Este estudo utilizou artigos publicados nas bases de dados Lilacs, PepSic e Scielo, em português, utilizando livres ou combinados os seguintes descritores: educação infantil, psicólogo escolar, desenvolvimento psicossocial. Após análise, concluiu-se que a inclusão do psicólogo escolar é fundamental para o desenvolvimento de todo o processo educativo, mas ao mesmo tempo faz-se necessário uma reafirmação das áreas de atuação do psicólogo para a comunidade escolar e para os próprios psicólogos.
O BOM PROFESSOR: ALGUMAS CARACTERÍSTICAS
Authors: Fuzeti Iara Lança , Marques Maria Martha Vieira , Rivelini Renata , Magalhães Karine Amaral , Sontag Daiane Aparecida
Published: October 2024

Identificar as características de um bom professor parece ser uma tarefa importante. O presente trabalho objetivou identificar as principais características de um bom professor. Os trabalhos pesquisados apontam para dois grandes grupos de comportamentos ou características: competência e relacionamento com os alunos. Mostram ainda que, entre os alunos do ensino superior e médio, as competências técnicas são as consideradas prioritárias, seguidas das de relacionamento; enquanto para os alunos do ensino fundamental, a prioridade foi para o bom relacionamento. A Análise do Comportamento Aplicada parece ser uma proposta interessante de formação docente.
Gerenciamento de uma rede pública utilizando a ferramenta Hotspot do Sistema Operacional RouterOS
Authors: Levy Guilherme
Published: October 2024

O presente artigo traz informações de componentes e métodos necessários para configuração de uma rede ao utilizar o sistema operacional RouterOS da empresa Mikrotik. Junto a isso, serão detalhados os conceitos de Firewall e Web Proxy. Em seguida será demonstrada a configuração e implementação da ferramenta Hotspot em uma rede pública acadêmica, com o objetivo de obter e gerenciar um maior controle de banda dos usuários, melhorando o tráfego de forma eficaz e bloqueando acessos não autorizados à rede. O artigo traz também um manual passo a passo de implementação do RouterOS e criação das regras básicas, webproxy, firewall e hotspot necessárias para a conclusão do projeto.
A importância das tecnologias da informação e comunicação na educação sob o olhar de professores
Authors: Folquenimm Viviane Maria
Published: October 2024

O presente artigo tem como objetivo evidenciar a importância das TICs na educação formal, especificamente na rede de educação básica de ensino público, analisando a opinião de educadores atuantes nessa área. Visa proporcionar aos leitores, informações e conjunturas sobre as Tecnologias da Informação e Comunicação, através das análises produzidas, refletir sobre ascontribuições possíveis para o avanço e desenvolvimento da educação básica, demonstrando suas diferentes formas de introdução das Tics no processo de ensino, com o intuito de contribuir não só para que a aprendizagem se torne mais significativa, mas para que todo o processo que envolve professor e aluno possa se tornar mais interativo e satisfatório para ambas as partes.
A EXISTÊNCIA E ANGÚSTIA A PARTIR DA MORTE DE DEUS: UMA PROPOSTA DE NIETZSCHE PARA A TRANSCENDÊNCIA DO HOMEM
Authors: Ribas Lucas
Published: October 2024

O presente artigo emerge com a proposta de explicitar como Friedrich Nietzsche sugere a existência baseada apenas na ação humana a partir da morte de Deus como tutor das ações do homem. Para tanto, o presente artigo tem como objetivo responder à seguinte problemática: Como se configura a existência humana a partir da morte de Deus e do Niilismo? Para abordar tal problemática faz-se necessário apresentar, inicialmente, a relação da filosofia nietzschiana com a religião, sobretudo as críticas ao cristianismo, que para ele deformam a existência do homem.
Manipulação craniana do quarto ventrículo (CV-4): uma revisão sistemática
Authors: Barbosa Vanessa Regina , Menna Vagner
Published: October 2024

Criada por Andrew Taylor Still em 1874, a osteopatia é mais que técnicas de manipulação, sua base está em princípios filosóficos buscando sempre a causa primaria dos sintomas, que é gerado através de adaptações e disfunções anatômicas, sendo assim recuperando a função da estrutura acometida, o organismo é colocado em sua capacidade de se auto regular e se auto curar (FAVARETO et al., 2019). A osteopatia craniana foi criada em 1930 por W. G. Sutherland. Onde evidenciou uma conexão e movimentos entre os ossos do crânio através de membranas, essas membranas que são a foice do cerebelo e tenda do cerebelo, conectadas com o sacro através da dura mater. Ainda ele avaliou a aplicação de forças restritivas e compreensivas no crânio onde fundamentou o movimento respiratório primário (JUNIOR et al., 2016). Uma técnica muito utilizada na osteopatia craniana é a manipulação do quarto ventrículo (CV-4) que afeta o diafragma e o controle autonômico da respiração (FAVARETO et al., 2019).
CONTO: TRADIÇÃO E RUPTURAS
Authors: Carbonera Ildo
Published: October 2024

O projeto de pesquisa e de análise - Conto: tradição e rupturas - previa as seguintes etapas: apresentação de conceitos e idéias a respeito de Tradição, Ruptura e Intertextualidade; observação e análise do processo de organização e realização de uma obra literária intitulada Missa do galo – variações sobre o mesmo tema; observação e análise de dados gerais, “exteriores”, relacionados aos novos contos, como títulos, nomes de personagens e epígrafes; leitura e análise das aproximações e afastamentos entre o conto “Missa do galo” e cada um dos novos contos elaborados a partir do modelo machadiano. Por exemplo, a segunda etapa do trabalho de pesquisa envolveria uma análise individualizada dos contos “Missa do galo”, de Machado de Assis e “Missa do galo”, de Nélida Piñon.
ASPECTOS A SEREM CONSIDERADOS NA GESTÃO, PLANEJAMENTO E ORGANIZAÇÃO DE UM SISTEMA EM EDUCAÇÃO À DISTÂNCIA
Authors: Rosa William Ferreira , Gabriel Katiuscia de Oliveira Francisco , Santana Lucas Fagundes
Published: October 2024

O presente trabalho vai revelar os aspectos a serem considerados na gestão, planejamento e organização de um sistema em educação à distância. O objetivo é apresentar a relação à importância da gestão, planejamento e organização em educação à distância para a instituição, com uma nova modalidade de ensino. O estudo será pautado em pesquisa bibliográfica. Uma abordagem comparativa entre o ensino presencial e a distância não pode ser tomada ipsis litteris, uma vez que sua variação está diretamente relacionada tanto à capacidade de organização acadêmica de cada instituição de ensino, quanto a características sócio-econômico-culturais locais e regionais.
AVALIAÇÃO DE MOBILIDADE E EQUILÍBRIO DE IDOSOS PARTICIPANTES DE UM GRUPO DE EXERCÍCIOS DA UNIDADE BÁSICA DE SAÚDE EM BOA VENTURA DE SÃO ROQUE (PR) – UM ESTUDO OBSERVACIONAL TRANSVERSAL
Authors: Miranda Jeniffer Alice , Santos Tartari Ana Paula
Published: October 2024

Objetivo: o estudo tem como finalidade avaliar o desempenho físico de idosos que participam de um programa de exercícios conduzido pelo setor de fisioterapia de uma unidade básica de saúde. Metodologia: A amostra consistiu em 15 indivíduos saudáveis com idade superior a 60 anos, de ambos os sexos. Utilizamos a Escala de Equilíbrio de Berg (EEB) e o teste Time Up and Go (TUG) como métodos de avaliação, realizando apenas uma coleta para analisar o desempenho físico dos participantes. Para análise estatística, empregamos o software IBM Statistics SPSS 20 e o Microsoft Excel para a criação de gráficos. Os resultados foram expressos em média, desvio-padrão e intervalo interquartil. Nas análises inferenciais, utilizamos a Correlação de Pearson e de Spearman, com um nível de significância de 95%. Resultados: indicaram um bom equilíbrio, com uma média de 53,13 ± 1,59 pontos na EEB, e uma boa mobilidade, com uma média de 6,08 ± 1,22 segundos no teste TUG. A correlação entre o TUG e o escore total da EEB foi negativa e forte, enquanto a correlação entre o TUG e a idade foi moderada. Conclusão: os idosos que participam do programa de exercícios apresentaram boa aptidão física, destacando-se pelo equilíbrio e mobilidade satisfatórios.
SATISFAÇÃO DOS USUÁRIOS QUANTO AO ATENDIMENTO FISIOTERAPÊUTICO DA CLÍNICA MUNICIPAL DE FISIOTERAPIA DO MUNICÍPIO DE PINHÃO-PR
Authors: Kriguer Braz Dhienniffer
Published: October 2024

Objetivo: Avaliar e analisar a satisfação dos pacientes do Sistema Único de Saúde (SUS) em relação ao atendimento prestado na clínica municipal de fisioterapia de Pinhão-PR, após terem se submetido ao tratamento fisioterapêutico. Método: Este estudo trata-se de uma pesquisa observacional transversal que utilizou amostragem por conveniência e convite verbal para avaliar a satisfação dos usuários da clínica municipal de fisioterapia em Pinhão, no estado do Paraná. Para essa avaliação, foi utilizado um questionário autoaplicável baseado no trabalho de Moreira; Borba e Mendonça (2007), composto por um total de quarenta e três questões divididas em duas partes distintas. Resultados: Foram um total de sessenta e seis amostras dos usuários da clínica municipal de fisioterapia em Pinhão-PR. Entretanto, sete questionários não foram respondidos na íntegra. Conclusão: A satisfação dos pacientes foi positiva para a maioria das questões, principalmente pela relação entre o fisioterapeuta e o paciente, que é alta credibilidade que mostra que uma boa comunicação com um profissional possibilita melhor aceitação e continuidade do tratamento. A maioria dos pacientes que responderam à pesquisa demonstraram que são satisfeitos com a experiência em fisioterapia, que realizaram seus tratamentos na clínica municipal de fisioterapia em Pinhão, no estado do Paraná.
EFEITOS A CURTO PRAZO DA MANIPULAÇÃO DA COLUNA TORÁCICA EM PACIENTES PORTADORES DE CERVICALGIA CRÔNICA
Authors: Fatima de Lima Erica , Silva Liseu
Published: October 2024

Objetivo: Determinar os efeitos a curto prazo da manipulação da coluna torácica na dor e funcionalidade em pacientes portadores de cervicalgia crônica. Método: A amostra foi composta por 14 indivíduos, de ambos os sexos, com idades entre 20 à 45 anos. Os participantes foram incluídos em um único grupo, onde todos receberam a manipulação AVBA (alta velocidade e baixa amplitude). A intensidade da dor foi medida através da escala de avaliação numérica (NRS-11) e a funcionalidade foi classificada através do índice de Incapacidade do Pescoço (NDI). Os dados estatísticos foram analisados por meio do Software IBM Statistics SPSS 20. Resultados: Houve uma redução significativa no nível de dor quando comparamos a pré (5,43 ± 1,65), pós (3,28 ± 1,81) e pós 7 dias de intervenção (2,57 ± 1,55), p= 0,000. A funcionalidade também apresentou uma diferença estatisticamente significativa, com média de 11,86 ± 4,45 no período pré, e de 6,57 ± 4,01 no pós, p=0,000. Conclusão: No presente estudo a manipulação apresentou resultados positivos a curto prazo na dor e na funcionalidade de pacientes portadores de cervicalgia crônica.