bluuebunny/crossref_metadata_2025 huggingface dataset:
Detection of polymorphism in growth differentiation factor 9 gene (GDF9) Exon1 and its association with litter size in local Iraqi goats
Authors: Hussen Ali Ola , Hassan Al- Azzawi Salih
Published: December 2022

Litter size is one of the most important economic traits in goats. Growth Differential Factor 9 (GDF9) Gene is suggested as a functional candidate for fertility, fecundity and twining rate. This study was performed to identify SNPs in exon1 of the GDF9 gene and their association with fertility traits in local Iraqi goats. The exon 1 of GDF9 was sequenced, and the SNP (Single nucleotide polymorphism ) was determined in 36 local Iraqi goats. Then the association analyses between polymorphic locals of GDF9 and litter size were performed using the chi-square analysis procedure. The result shows that mutation (C 1902 G) was significantly associated with litter size in local Iraqi goats and the location of C1902 G mutation with three genotypes CC, CG and GG. A significant effect was found for birth weight, weaning weight and twin ratio, where the homozygous dominant genotype outperformed CC. A significant impact was seen for fertility and mortality, where CC topped CG and GG in fertility percentage and superiority of CG over CC and GG in mortality rate. The results preliminarily demonstrated that GDF9 was a critical gene affecting the fecundity of local Iraqi goats and that (C 1902 G) could be a potential genetic marker. Keywords: GDF9 gene, litter size, polymorphism, Iraqi goats
The Use of Passive Smartphone Data to Monitor Anxiety and Depression Among College Students in Real-World Settings: Protocol for a Systematic Review
Authors: Girousse Eva , Vuillerme Nicolas
Published: December 2022

Background

College students are particularly at risk of depression and anxiety. These disorders have a serious impact on public health and affect patients’ daily lives. The potential for using smartphones to monitor these mental conditions, providing passively collected physiological and behavioral data, has been reported among the general population. However, research on the use of passive smartphone data to monitor anxiety and depression among specific populations of college students has never been reviewed.

Objective

This review’s objectives are (1) to provide an overview of the use of passive smartphone data to monitor depression and anxiety among college students, given their specific type of smartphone use and living setting, and (2) to evaluate the different methods used to assess those smartphone data, including their strengths and limitations.

Methods

This review will follow the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. Two independent investigators will review English-language, full-text, peer-reviewed papers extracted from PubMed and Web of Science that measure passive smartphone data and levels of depression or anxiety among college students. A preliminary search was conducted in February 2022 as a proof of concept.

Results

Our preliminary search identified 115 original articles, 8 of which met our eligibility criteria. Our planned full study will include an article selection flowchart, tables, and figures representing the main information extracted on the use of passive smartphone data to monitor anxiety and depression among college students.

Conclusions

The planned review will summarize the published research on using passive smartphone data to monitor anxiety and depression among college students. The review aims to better understand whether and how passive smartphone data are associated with indicators of depression and anxiety among college students. This could be valuable in order to provide a digital solution for monitoring mental health issues in this specific population by enabling easier identification and follow-up of the patients.

Trial Registration

PROSPERO CRD42022316263; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=316263

International Registered Report Identifier (IRRID)

DERR1-10.2196/38785
Prepandemic Antivaccination Websites' COVID-19 Vaccine Behavior: Content Analysis of Archived Websites
Authors: Kaplan Samantha , von Isenburg Megan , Waldrop Lucy
Published: December 2022

Background

The onset of the COVID-19 pandemic and the concurrent development of vaccines offered a rare and somewhat unprecedented opportunity to study antivaccination behavior as it formed over time via the use of archived versions of websites.

Objective

This study aims to assess how existing antivaccination websites modified their content to address COVID-19 vaccines and pandemic restrictions.

Methods

Using a preexisting collection of 25 antivaccination websites curated by the IvyPlus Web Collection Program prior to the pandemic and crawled every 6 months via Archive-It, we conducted a content analysis to see how these websites acknowledged or ignored COVID-19 vaccines and pandemic restrictions. Websites were assessed for financial behaviors such as having storefronts, mention of COVID-19 vaccines in general or by manufacturer name, references to personal freedom such as masking, safety concerns like side effects, and skepticism of science.

Results

The majority of websites addressed COVID-19 vaccines in a negative fashion, with more websites making appeals to personal freedom or expressing skepticism of science than questioning safety. This can potentially be attributed to the lack of available safety data about the vaccines at the time of data collection. Many of the antivaccination websites we evaluated actively sought donations and had a membership option, evidencing these websites have financial motivations and actively build a community around these issues. The content analysis also offered the opportunity to test the viability of archived websites for use in scholarly research. The archived versions of the websites had significant shortcomings, particularly in search functionality, and required supplementation with the live websites. For web archiving to be a viable source of stand-alone content for research, the technology needs to make significant improvements in its capture abilities.

Conclusions

In summary, we found antivaccination websites existing prior to the COVID-19 pandemic largely adapted their messaging to address COVID-19 vaccines with very few sites ignoring the pandemic altogether. This study also demonstrated the timely and significant need for more robust web archiving capabilities as web-based environments become more ephemeral and unstable.
The Effect of Vitamin D on Inflammation and Dyslipidemia in Type 2 Diabetes Mellitus: Protocol for a Systematic Review and Meta-analysis of Randomized Controlled Trials
Authors: MacGirlley Rizqah , Mokgalaboni Kabelo
Published: December 2022

Background

Type 2 diabetes mellitus is a chronic disease that contributes to an increasing global burden on the health system. It has a high chance of leading to macrovascular complications and cardiovascular disease. As an inflammatory condition, it would be essential to target inflammatory pathways when developing therapeutic drugs for type 2 diabetes mellitus.

Objective

We aimed to evaluate the effect of vitamin D on markers of inflammation and lipid profile among adult patients with diabetes.

Methods

A systematic review will seek studies published on Embase, Google Scholar, PubMed, Web of Science, and Science Direct. This planned systematic review and meta-analysis will be limited to randomized controlled trials; moreover, the search will include published studies regarding the effects of vitamin D on pro-inflammatory cytokines and lipid profiles. The review will include studies published from inception until December 30, 2022. The study identification and selection will be based on the eligibility criteria by 2 independent reviewers. Additionally, a meta-analysis will only be performed if more than 2 studies are available and explore the same outcomes, and this will be analyzed using RevMan (version 5.4.1). The quality and risk of bias will be assessed following the Cochrane risk of bias tool and Jadad checklist.

Results

The process for searching literature review has already started, and this is conducted independently by 2 reviewers using a predefined eligibility and “participants, intervention, comparator, and outcome” criteria. This systematic review and meta-analysis will not require any direct involvement of patients and the public; thus, no ethical approval was required.

Conclusions

The findings obtained from the proposed study will be presented in scientific seminars, journal clubs, and conferences and published in peer-reviewed journals.

Trial Registration

International Platform of Registered Systematic Review and Meta-analysis Protocols INPLASY202260022; https://inplasy.com/?s=INPLASY202260022

International Registered Report Identifier (IRRID)

PRR1-10.2196/42193
Investigating the Secondary Use of Clinical Research Data: Protocol for a Mixed Methods Study (Preprint)
Authors: Waithira Naomi , Kestelyn Evelyne , Chotthanawathit Keitcheya , Osterrieder Anne , Mukaka Mavuto , Lang Trudie , Cheah Phaik Yeong
Published: December 2022

BACKGROUND

The increasing emphasis to share patient data from clinical research has resulted in substantial investments in data repositories and infrastructure. However, it is unclear how shared data are used and whether anticipated benefits are being realized.

OBJECTIVE

The purpose of our study is to examine the current utilization of shared clinical research data sets and assess the effects on both scientific research and public health outcomes. Additionally, the study seeks to identify the factors that hinder or facilitate the ethical and efficient use of existing data based on the perspectives of data users.

METHODS

The study will utilize a mixed methods design, incorporating a cross-sectional survey and in-depth interviews. The survey will involve at least 400 clinical researchers, while the in-depth interviews will include 20 to 40 participants who have utilized data from repositories or institutional data access committees. The survey will target a global sample, while the in-depth interviews will focus on individuals who have used data collected from low- and middle-income countries. Quantitative data will be summarized by using descriptive statistics, while multivariable analyses will be used to assess the relationships between variables. Qualitative data will be analyzed through thematic analysis, and the findings will be reported in accordance with the COREQ (Consolidated Criteria for Reporting Qualitative Research) guidelines. The study received ethical approval from the Oxford Tropical Research Ethics Committee in 2020 (reference number: 568-20).

RESULTS

The results of the analysis, including both quantitative data and qualitative data, will be available in 2023.

CONCLUSIONS

The outcomes of our study will offer crucial understanding into the current status of data reuse in clinical research, serving as a basis for guiding future endeavors to enhance the utilization of shared data for the betterment of public health outcomes and for scientific progress.

CLINICALTRIAL

Thai Clinical Trials Registry TCTR20210301006; https://tinyurl.com/2p9atzhr

INTERNATIONAL REGISTERED REPORT

DERR1-10.2196/44875
Policy Transfer Through Return Migration: Lesson From Indonesian Returnees
Authors: Arinda Violita Sinda , Fathurrahman Reza
Published: December 2022

This article investigates the extent to which policy transfer activities facilitated by Indonesian skilled returnees after finishing their studies in Germany can support various local actors in accelerating developmental progress in their homeland. By using the five-dimensional policy transfer (Evans, 2017), this study found that returnees strengthen the working environment by promoting exchange of knowledge, improving current work methods, and advocating for most common forms of transfer including knowledge sharing, experiences, and networks that they had while abroad. The research also found that most cases of successful policy transfer adoption were characterized by hybridization of new ideas with existing policy and institutional framework in organizations that participated in the program.
NEW MODEL FOR LOCAL POST DISASTER TOURISM GOVERNANCE: Evidence from Indonesia’s Merapi Volcano
Authors: Zaenuri Muchamad
Published: December 2022

This article examines the dynamics of local post-disaster tourism governance in areas on the foothills of Merapi Volcano in Yogyakarta, Indonesia, which is one of the world’s most intensively active volcanoes. In this research, the author invites the readers to discuss the success achieved in local collaboration through transforming disaster life into a profitable tourism site. They face difficult situations amid government limitations in handling this post-disaster development. Using qualitative descriptive analysis, this study offers a new local-based collaboration model, especially for the post-disaster tourism governance in developing countries. Result of the study showed that local collaboration cannot be achieved in an instant, rather involves a process that is influenced by local wisdom. This article makes positive contribution to public policy literature and is essential for policymakers at the lower level and concerned about local-based development and empowerment
El Bosque de Chapultepec: un parque en transformación
Authors: Pérez Bertruy Ramona I.
Published: December 2022

Evolución histórica del Bosque de Chapultepec para contar cuándo se transforma en un parque moderno al estilo paisajista inglés, con la ampliación de sus secciones hasta la conformación del actual proyecto de recuperación y modernización.
La reinterpretación del espacio: Cineteca Poniente. Entrevista con Mauricio Rocha
Authors: Zamora Centl
Published: December 2022

Entre los espacios que se están generando con el proyecto “Bosque de Chapultepec: Naturaleza y cultura”, destaca la propuesta de una nueva cineteca, un espacio que apuesta por la convivencia y el séptimo arte como recursos para acercarse y acercar a la sociedad. La Cineteca Poniente se implanta en la nueva Cuarta Sección del Bosque, donde logra desarrollar un espacio cultural a través de la interpretación y adaptación de las edificaciones preexistentes. Nos reunimos con Mauricio Rocha, quien está a cargo de este proyecto e igualmente se encuentra involucrado en la planeación de la Cuarta Sección, para platicar más sobre las cualidades del proyecto.Palabras clave: Bosque de Chapultepec, Cineteca Poniente, Cuarta Sección, estructuras existentes, espacio público, ríos vivos, cultura
Mobile Phone Detection and Notification for The Prevention of Car Accidents
Authors: Zope Hrishikesh , Jain Harshita , Jain Hruday , Raut Shital
Published: December 2022

Abstract: The use of mobile devices can easily divert a driver's attention away from the road. Dangerous driving, such as texting and driving, can cause havoc in traffic and jeopardize safety. The goal of this project is to develop an accident-avoidance system that can detect the presence of a mobile phone in the driver's hand by installing an in-car camera facing the driver and running a YOLOv3-Tiny algorithm for mobile phone detection. In addition, the model will issue an audio alert to the driver and use face detection algorithms to determine the driver's identity. Twilio APIs are being used to send live messages to car owners about the actions taken using the car's location information.
Study of Factors affecting the National Anonymously: Dark Web
Authors: Sankpal Akshay , Shivnkar Chetan , Pawar Priyanka , Gade Pranjali
Published: December 2022

Abstract: This paper talks about how the dark web is utilized to genuine purposes just as to hide the noxious exercises or criminalism. The Dark Web is at the focal point of the discussion about whether online namelessness ought to be kept up despite the criminal behavior that it empowers. This paper will limit its degree by concentrating exclusively on the national contemplations of the Dark Web, and not those issues that dig into the domain of local law implementation. Drug dealing, firearms, fake products, unlawful erotic entertainment, and so forth these are issues that this paper characterizes as falling into the domain.
Unit for Splitting Degraded Mountain Meadows and Pastures Based on a Mini Tractor
Authors: Dzhibilov S. M. , Guluyeva L. R.
Published: December 2022

Soil splitting is used to prevent water and wind erosion of soils, improve their water-air regime in mountain meadows and pastures. It reduces soil loss, improves plants moisture supply, affects herbage species composition and increases fodder lands yield. The advantages of a small-sized unit have been described ensuring gentle splitting with the formation of water-absorbing splits on the slopes. (Research purpose) To create a small-sized maneuverable splitter for mountain meadows and pastures, to determine its agrotechnical parameters, to give a graphic-analytical substantiation of the splitting working process in areas with a slope of up to 12 degrees. (Materials and methods) A technical examination of the unit laboratory sample was carried out at an altitude of 1540 meters above the sea level. The slitter working width was determined by two passes at 25 points located at the intervals of at least 1 meter in the unit movement direction. (Results and discussion) A splitter for the mountain area was built on the basis of a Feng Shou 180 mini-tractor, reducing the load on the soil. An optimal arrangement scheme for the splitter working bodies has been developed when moving along a slope. The scheme of the unit movement on the slope was substantiated. The following technological parameters were set: the distance between the splits is 1,000 millimeters, the depth of slip cutting is 200220 millimeters, the split width is 10-30 millimeters. (Conclusions) It was determined having penetrated into the soil, the shift in the reaction of the working body located on the slope top side of the tractor axis stabilizes the position of the unit when moving across the slope, preventing it from sliding down. It was found that being 1,000 mm apart from each other and of the width of not more than 35 mm, the splitter cutting-knives do not destroy the turf layer, do not damage the edges of the slot. The use of a Feng Shou 180 mini-tractor enabled to decrease the unit weight load of on the agrocenosis during movement.
Behavioral Intention Pada Aplikasi Pemesanan Makanan Gofood, Grabfood dan Shopeefood
Authors: Lusyana  , Wiastuti Rachel
Published: December 2022

Pertumbuhan transaksi secara online melalui media telepon genggam dalam bidang makanan dan minuman meningkat cukup besar yang berdampak pada munculnya aplikasi pemesanan makanan atau food delivery apps. Penelitian ini bertujuan untuk menganalisis hubungan convenience motivation, attitude, dan behavioral intention pada pengguna aplikasi pemesanan makanan yang popular di Indonesia yaitu GoFood, GrabFood, dan ShopeeFood. Penelitian ini menggunakan pendekatan kuantitatif. Sampel dalam penelitian ini adalah 84 penguna GoFood, 95 pengguna GrabFood, dan 16 pengguna ShopeeFood. Instrumen penelitian yang digunakan adalah e-kuesioner yang sifatnya tertutup (close-ended questions) dengan skala Likert ordinal. Teknik survei digunakan untuk mengumpulkan data primer dan studi pustaka dilakukan untuk mengumpulkan data sekunder. Data dianalisis menggunakan teknik path analysis (analisis jalur) dan Uji hipotesis menggunakan uji T. Hasil penelitian menunjukkan bahwa pada GoFood dan GrabFood, convenience motivation memiliki pengaruh positif terhadap behavioral intention melalui attitude sebagai mediasi. Namun hal ini berbeda pada ShopeeFood dimana attitude tidak berperan sebagai mediasi antara convenience motivation dan behavioral intention.
Corporate Social Responsibility in Small and Medium Sized Enterprises Hotel in Seminyak Area
Authors: Dewi A.A. Ayu Indah Kusuma , Sudiksa I Nyoman , Kalpikawati Ida Ayu , Pinaria Ni Wayan Chintia
Published: December 2022

This research is motivated by the importance of CSR disclosure among SMEs hotel in the Seminyak area that has been implementing CSR. The purpose of this study is to explore the implementation of CSR activities, the media uses to disclose the CSR activities, and the perceived barriers to disclosing CSR activities on the website. This research is a qualitative research. The population would be chosen through observation by direct phone call to each SMEs hotel area with CSR activities and 5 SMEs hotel have been chosen. The data needed was gathered by doing interviews to the owner or manager of each SMEs hotel. The data were analyzed through three activities, such as data reduction, data display, conclusions, and method triangulation. The results revealed SMEs hotel predominantly undertake corporate social marketing, community volunteering, and corporate philanthropy, then used meetings, word of mouth, briefing, WhatsApp, Instagram, and email to disclose their CSR activities. SMEs hotel perceived barriers in disclosing their CSR on the website are CSR disclosure is not needed, CSR disclosure is not their priority, and lack of human resources.
HUBUNGAN KEMATANGAN EMOSI DENGAN FORGIVENESS PADA SISWA SMAN 1 LEMBAH GUMANTI
Authors: Fitriany Rany , Desra Hilda Hayatul , Candra Ifani
Published: December 2022

ABSTRACTIntroduction This study aims to determine the relationship between emosional maturity and forgiveness in students of SMAN 1 Lembah Gumanti. The independent variable in this study is emosional maturity and the dependent variable is forgiveness.

Methods The measuring instrument used in this research is the emotional maturity scale and forgiveness scale. The population in this study were Students of SMAN 1 Lembah Gumanti total 0f 460 students. The sampling technique in this study used a simple random sampling technique. The sample in this study were 171 people students of SMAN 1 Lembah Gumanti.

Results The validity coefficient of emotional maturity scale obtained corrected item-total correlation values ranging from 0.327 to 0.729 while the reliability coefficient is 0.903. The results of the validity coefficient on the scale forgiveness with corrected item-total correlation values ranging from 0,324 to 0.748 while the reliability coefficient is 0.925. Based on data analysis, a correlation value of 0.452 with a significance level of 0.000 was obtained, which means the hypothesis is accepted.

Kesimpulan This shows that there is a significant positive relationship with a high level between emosional maturity and forgiveness into students SMAN 1 Lembah Gumanti. The effective contribution of the emosional maturity variable on the forgiveness variable is 20%.

Keywords: Maturity Emosional, Forgiveness, Students.

Abstrak

Pendahuluan Penelitian ini bertujuan untuk mengetahui hubungan antara kematangan emosi dengan forgiveness pada siswa SMAN 1 Lembah Gumanti. Variabel bebas dalam penelitian ini adalah kematangan emosi dan variabel terikatnya adalah forgiveness.

Metode Alat ukur yang digunakan dalam penelitian ini adalah skala kematangan emosi dan skala forgiveness. Populasi dalam penelitian ini adalah siswa di SMAN 1 Lembah Gumanti yang berjumlah 460 orang siswa. Teknik pengambilan sampel dalam penelitian ini menggunakan tehnik simple random sampling. Sampel dalam penelitian ini adalah 171 orang siswa di SMAN 1 Lembah Gumanti.

Hasil Koefisien validitas pada skala kematangan emosi dengan nilai corrected item-total correlation berkisar antara 0,327 sampai dengan 0,729 sedangkan koefisien reliabilitasnya sebesar 0,903. Hasil koefisien validitas pada skala Forgiveness dengan nilai corrected item-total correlation berkisar antara 0,324 sampai dengan 0,748, sedangkan koefisien reliabilitasnya sebesar 0,925. Berdasarkan analisis data diperoleh nilai korelasi sebesar 0,452 dengan tingkat signifikansi 0,000 yang berarti hipotesis diterima.

Kesimpulan Hal ini menunjukkan bahwa ada hubungan positif yang signifikan dengan tingkat yang tinggi antara Kematangan emosi dan forgiveness pada pada siswa SMAN 1 Lembah Gumanti. Kontribusi efektif dari variabel kematangan emosi pada variabel Forgiveness adalah sebesar 20%.

Kata kunci: Kematangan Emosi , forgiveness, Siswa.
Putusan Pengadilan sebagai Objek Penulisan Artikel Ilmiah
Authors: Shidarta Shidarta
Published: December 2022

Specific knowledge and abilities are required for the design and technical writing of scientific papers that are the subject of judicial rulings. This document intends to provide a roadmap for academics who want to publish articles in scientific publications about the study of court decisions. This paper covers the issue’s triggering variables, which serve as criteria for why a decision is intriguing and worthy of investigation. This paper then goes on to cover in detail numerous technical components of writing systematics, starting with the backdrop and problem formulation, literature review, analysis, and conclusions and recommendations. From all these discussions, this paper emphasizes that the problem formulation (research question) is a very crucial stage in the study of decisions. This formulation must be paid an adequate background that identifies the existence of legal problems in the decision. Through this formulation, it will also be known whether the study leads to a type of research that is merely descriptive, descriptive-analytical, or analytical-prescriptive. Researchers can anticipate and overcome numerous hurdles that may arise when performing a court decision review according to the author’s explanation.

Abstrak

Desain dan teknis penulisan artikel ilmiah yang berobjekkan putusan pengadilan membutuhkan pengetahuan dan keterampilan yang cukup khas. Tulisan ini bertujuan untuk menawarkan satu panduan yang dapat diikuti oleh peneliti yang ingin menuliskan artikel kajian putusan pengadilan itu ke dalam jurnal ilmiah. Tulisan ini membahas tentang faktor-faktor pemantik isu yang menjadi kriteria mengapa suatu putusan menarik dan layak untuk diteliti. Tulisan kemudian menguraikan secara deskriptif mengenai beberapa segi teknis yang layak dicermati yang berkorelasi dengan sistematika penulisan mulai dari latar belakang dan rumusan permasalahan, tinjauan literatur, analisis, serta kesimpulan dan saran. Dari semua bahasan tersebut, tulisan ini menekankan bahwa perumusan masalah adalah tahapan yang sangat krusial di dalam kajian putusan. Rumusan ini wajib diberi latar belakang yang memadai yang mengidentifikasi adanya problematika hukum di dalam putusan tersebut. Melalui rumusan itu juga akan diketahui apakah kajian itu mengarah ke tipe penelitian yang sekadar deskriptif, deskriptif-analitis, atau analitis-preskriptif. Melalui paparan dari artikel ini, para peneliti diharapkan dapat mengantisipasi dan mengatasi berbagai kendala yang mungkin dihadapi dalam melakukan kajian putusan pengadilan.
PENYULUHAN TENTANG PENTINGNYA BIJAK DALAM BERBAHASA DI MEDIA SOSIAL BEBRBASIS NEUROSAINS BAGI GURU DAN SISWA
Authors: F. Yusep Ahmadi , Aeni Eli Syarifah , Mahardika Reka Yuda , Aryana Suhud
Published: December 2022

This dedication is motivated by the many legal problems that are motivated by the unwise language on social media. One of them, social media at this time is often misused by humans to spread false news and spread hatred. Not infrequently people who do not have the awareness and knowledge about the use of social media are carried away by the current. As a result, the community will potentially get into legal problems. Currently, the use of social media that contains such violations will be subject to the ITE Law. The purpose of this service is to provide counseling as a solution for people who are considered to still do not have the awareness and language skills on social media wisely, well, and politely. This service method is by providing planned and structured counseling to teachers and students of the Miftahul Ihsan Al Banjary Foundation, Banjar City. The results of observations and questionnaires showed that the teacher and student participants were enthusiastic and gained knowledge about polite language on social media. It is hoped that this activity will provide knowledge and increase the awareness of teachers and students of the Miftahul Ihsan Al Banjary Foundation in Banjar City in wise and polite language on social media.
A prospective study evaluating fluorescence guided minimally invasive paediatric solid tumour surgery using indocyanine green.
Authors: Pachl Maximilian , CV Anna Harris , S Choudhury
Published: December 2022

Background  Indocyanine green (ICG) fluoresces in the near infra-red
(NIR) spectrum. It is widely used in adult oncological surgery for
identification of tumor margins and lymph node sampling. However, its
use in the pediatric population is limited. This is the first study in
children to assess its feasibility in minimally invasive surgery (MIS)
for oncological disease Methods  This was an open label, prospective,
single centre, feasibility study recruiting consecutive patients
eligible for MIS tumor resection. ICG was injected intravenously at
induction of anaesthesia and/or intra-parenchymally for patients having
tumor nephrectomy. Patient demographics, intraoperative appearances,
nodal fluorescence, post-operative histopathology, and surgeon Likert
ratings were collected. Results Seventeen patients conformed to the
inclusion criteria. Five had a Wilms tumor, 4 had lung metastases and 8
had other tumors (neuroblastoma, inflammatory myofibroblastic tumor,
ganglioneuroma, phaeochromocytoma, adrenal tumor). For those having
lymph node sampling, a median of 8(3-9) nodes were sampled. Lung
metastases were easily identifiable, and all had negative margins.
Tumors containing viable disease fluoresced and were completely
resected, whilst benign and heavily treated tumors were afluorescent.
There were no adverse events relating to ICG. Conclusion  Based on this
small sample, injection of ICG during induction of anaesthesia is safe
and effective in showing tumor margins in patients who have had little
or no neoadjuvant chemotherapy as well as in metastectomy in Wilms and
osteosarcoma. Its use in renal tumor resection results in adequate nodal
sampling. Further studies are needed to confirm these preliminary
results.
Host genomic variation shapes gut microbiome diversity in threespine stickleback fish
Authors: Small Clayton , Beck Emily , Currey Mark , Tavalire Hannah , Bassham Susan , Cresko William
Published: December 2022

Variation among host-associated microbiomes is well documented across
species, populations, and individuals. Understanding relationships
between host-genetic and microbial variation is important for predicting
coevolutionary dynamics between hosts and their microbiota and is also
biomedically relevant to understanding why some humans are more
susceptible to chronic disorders like Inflammatory Bowel Diseases (IBD).
Unfortunately, the relative contributions of host genetics and the
environment to microbiome variation have been difficult to study. Human
research shows that genetic variation influences microbiome differences
but confounding environmental effects cannot be controlled
experimentally. Isogenic laboratory models can be used in controlled
environments but often focus on large-effect mutations and do not
recapitulate genetic variation observed in nature. Thus, although
important factors impacting the microbiome have been identified, few
studies have tested for the direct influence of natural host-genetic
variation on microbiome differences within a controlled environment. To
address this, we performed a common garden experiment using laboratory
lines of genetically divergent populations of threespine stickleback
fish - an outbred model organism commonly used for determining the
genetic basis of complex traits in the context of natural genetic
variation. Using germ-free derivation of divergent lines and hybrids
between them in this experimental framework, we detected a clear,
positive association between stickleback genetic dissimilarity and
microbiome dissimilarity. With RAD-seq data we identified regions of the
genome that contributed most significantly to this relationship.
Importantly, we also highlight that heritable morphological traits like
body size -when correlated with microbiome composition - need
consideration in future host-associated microbiome studies.
Lumbosacral junction congenital kyphosis in an adult patient: a case report
Authors: Eslami Arvin , Chehrassan Mohammadreza , Alimoghadam Shaya , Shakeri Mohammadreza
Published: December 2022

This is an extremely rare case of congenital lumbosacral junction
kyphosis (CLSJK) in a 40-year-old woman due to S1-S2 hemivertebra.
Performing surgery has helped to improve neurological disturbances but
not completely after 1 year of follow-up.
Dendritic network location mediates detritivore community structure and associated processing of leaf litter in a riverine ecosystem
Authors: Wahl Charles , Brown Bryan , Swan Christopher
Published: December 2022

Historically, studies have examined how local habitat, resources and
species interactions influence community structure in stream ecosystems.
Increasingly, though, attention has turned to understanding how regional
factors (e.g. dispersal) interact with local conditions to influence
communities. Often dispersal of organisms occurs in spatially
constrained habitats, which can drastically influence community
assembly. Dendritic networks are an example, and have a branching
spatial configuration with some branches of the system more connected to
others, making dispersal easier, while other locations are more
isolated. As interest in multi-scale community assembly mechanisms has
increased, less work has focused on the relationship between community
assembly and ecosystem processes. Here, we sought to understand how
consumer-resource interactions unfold in river networks. We predicted
that stream network location would mediate detritivore (shredder)
richness and abundance, and in turn would be associated with a shift in
decomposition of organic matter (leaf litter). To examine this, we
manipulated leaf litter species in isolated (headwaters) and connected
(mainstem) stream reaches. We found that shredder richness and abundance
were influenced by both leaf litter quality and network location.
Headwater environments supported a stronger consumer-resource
relationship, and shredder communities were further richer and more
abundant. This was not the case in mainstem locations. In these
relatively harsher environments, we offer that shredders did not appear
to be actively feeding on the resources, but rather utilizing leaf
litter more for habitat. Our results suggest river network position has
important implications for how ecosystem function changes across
spatially constrained environments.
The “brain-heart-gut” axis and novel mechanisms of future cardiovascular disease
Authors: Hu Chunsong
Published: December 2022

Cardiovascular disease (CVD) is a leading cause of morbidity and
mortality in the globe. Both established cardiovascular disease (eCVD)
and future CVD (fCVD) need to further explore the mechanisms. This
article briefly introduces current major studies on axis and CVD, which
were published in cardiovascular journals and non-cardiovascular
journals (Table 1 & Table 2), and brings up and discusses the new
origins of fCVD linking to major risk factors in early life due to
unhealthy “environment-sleep-emotion-exercise-diet” intervention
[E(e)SEEDi] lifestyle referred as to a “Golden Hoop Curse”, and
the “brain-heart-gut” axis—a fresh theory on novel mechanisms of
fCVD (Figure 1 & Figure 2), which are mediated by E(e)SEEDi lifestyle
and microbiome. As a new theory, the “brain-heart-gut” axis will help
us to earlier and better prevent and control both eCVD and fCVD with
healthy E(e)SEEDi lifestyle.
Study On the Mechanism of Atmospheric Electric Field Anomalies Before Earthquakes
Authors: su jianfeng , chen hai
Published: December 2022

Negative abnormal changes of atmospheric electric field have been
monitored many times before earthquakes, especially before large
earthquakes. However, its mechanism has not been clearly concluded yet.
Based on the comparative analysis of the positive anomaly
characteristics of atmospheric electric field before lightning and
geoelectric field before earthquakes in earthquake areas, this paper
concludes that the negative anomalies of atmospheric electric field
before earthquakes are caused by the rise of the geoelectric potential
in earthquake areas, and the areas with the abnormal rise of the
geoelectric potential are potential earthquake areas. Based on the
inference above , this paper further proposes a comprehensive earthquake
early warning method with station network layout by geoelectric field
instruments in combination with the atmospheric electric field data
monitored by Electric Field Mills (EFMs). The research results will
provide a possible reference for exploring the mechanism of earthquake
generation, and will be help to explore earthquake early warning.
PENGARUH PELATIHAN SKIPPING DUA KAKI DAN AKSELERASI SPRINT TERHADAP KEMAMPUANMENGGIRING BOLA DAN KETEPATAN SHOOTING PADA SEPAKBOLA
Authors: Mahanggara I Putu , Sudiana I Ketut , Dharmadi Made Agus
Published: December 2022

Penelitian ini bertujuan untuk mengetahui: 1) perbedaan pengaruh pelatihan skipping dua kaki dan akselerasi sprint terhadap kemampuan menggiring bola dan ketepatan shooting pada sepakbola, 2) perbedaan pengaruh pelatihan skipping dua kakidengan kelompok kontrol terhadap kemampuan menggiring bola dan ketepatan shooting pada sepakbola, 3) perbedaan pengaruh pelatihanakselerasi sprint dengan kelompok kontrol terhadap kemampuan menggiring bola dan ketepatan shooting pada sepakbola. Jenis penelitian yang digunakan dalam penelitian ini adalah eksperimen semu (quasi experimental). Subyek penelitian berjumlah 45 orang ditentukan dengan teknik ordinal pairing. Teknik analisis data menggunakan manova taraf signifikansi 0,05. Instrumen penelitian menggunakan tes dribbling untuk mengukur kemampuan menggiring bola dan tes shooting ke sasaran untuk mengukur keterampilan shooting. Hasil penelitian menunjukkan: 1) tidak terdapat perbedaan pengaruh yang signifikan antara metode pelatihan skipping dua kaki dan akselerasi sprint terhadap kemampuan menggiring bola dan ketepatan shootingpada peserta sepakbola dengan nilai sig (0.676) > α (0,05),dan nilai sig shooting (0,299) > α (0,05), 2) Adanya perbedaan pengaruh yang signifikan antara metode pelatihan skipping dua kaki dengan kelompok kontrol terhadap kemampuan menggiring bola dan ketepatan shooting pada peserta sepak bola nilai sig (0.042) > α (0,05), dan nilai sig shooting (0.005) < α (0,05), 3)  Adanya perbedaan pengaruh yang signifikan antara metode pelatihanak selerasi sprint dengan kelompok control terhadap kemampuan menggiring bola dan ketepatan shooting pada peserta sepakbola nilai sig (0.04) > α (0,05),dan nilai sig shooting (0.042) < α (0,05).  Simpulan dari penelitian ini: 1) Tidak terdapat perbedaan pengaruh yang signifikan terhadap hasil kemampuan menggiring bola dan ketepatan shooting pada peserta yang mendapatkan pelatihan skipping dua kaki dan akselerasi sprint, 2) Terdapat perbedaan pengaruh yang signifikan terhadap hasil kemampuan menggiring bola dan ketepatan shooting pada peserta yang mendapatkan pelatihan skipping dua kakidengan kelompok kontrol, 3) Terdapat perbedaan pengaruh yang signifikan terhadap hasil kemampuan menggiring boladan ketepatan shooting pada peserta yang mendapatkan pelatihan akselerasi sprint dengan kelompok kontrol. Disarankan kepada pembina/pelatih olahraga dapat menggunakan metode pelatihan skipping dua kaki dan akselerasi sprint sebagai salah satu alternatif untuk meningkatkan kemampuan menggiring bola dan ketepatan shooting pemain sepakbola.
THE EFFECT OF PROBLEM BASED LEARNING (PBL) MODEL ON SOCIAL STUDIES LEARNING OUTCOMES FOR FIFTH GRADE STUDENTS AT SDN 03 TIUMANG, DHARMASRAYA REGENCY
Authors: Utami Visi Ofi
Published: December 2022

The implementation of one of the learning models that can affect students is the Problem Based Learning (PBL) model. This model presents a real problem for students as the beginning of learning. This study aims to determine the effect of the Problem Based Learning (PBL) model on social studies learning outcomes for fifth grade students at SDN 03 Tiumang, Dharmasraya Regency. This research is classified into quantitative research. The research design used by the author is a Quasi Experimental Design in the form of Posttest Only Control Design. The subjects in this study were all fifth grade students at SDN 03 Tiumang. Then calculated using a simple paired t-test. Based on the results of the paired sample t test, it is known that the significant (2-tailed) value is 0.141>0.05, then Ho is rejected and Ha is accepte, it can be concluded that Ho is rejected and Ha is accepted, so it means that there is an effect of the Problem Based Learning (PBL) model on social studies learning outcomes for fifth grade students at SDN 03 Tiumang, Dharmasraya Regency.
Model Pembelajaran Kooperatif Tipe NHT dalam Setting lesson study dan Pengaruhnya Terhadap Hasil Belajar Pendidikan Jasmani Mahasiswa
Authors: Abadi Ida Bagus Gede Surya , Wiyasa I Komang Ngurah , Putra DB. Kt. Ngr. Semara
Published: December 2022

Masalah pembelajaran Pendidikan Jasmani khususnya atletik pada nomor lompat jauh gaya jongkok belum memahami secara konseptual, maka mahasiswa tersebut perlu mendapatkan proses pembelajaran untuk meningkatkan hasil belajar Pendidikan Jasmani pada nomor lompat jauh gaya jongkok. Penelitian ini bertujuan untuk menganalisis model pembelajaran kooperatif tipe NHT dalam setting lesson study dan pengaruhnya terhadap hasil belajar pendidikan jasmani mahasiswa. Penelitian yang dilakukan ini menggunakan jenis penelitian eksperimen semu dengan rancangan non-equivalent control group design. Populasi dalam penelitian ini adalah seluruh mahasiswa semester IV. Sampel penelitian ditentukan dengan teknik random sampling. Sampel penelitian terdiri dari dua kelompok, yaitu kelompok eksperimen dan kelompok kontrol. Metode pengumpulan data menggunakan metode tes. Data yang terkumpul dianalisis dengan uji menggunakan analisis uji-t. Hasil penelitian menunjukkan bahwa terdapat perbedaan yang signifikan hasil belajar pendidikan jasmani pada mahasiswa yang dibelajarkan dengan model NHT dalam setting lesson study dan mahasiswa yang dibelajarkan secara konvensional. Implikasi penelitian ini diharapkan dapat meningkatkan belajar pendidikan jasmani pada mahasiswa.
BeFind: Start-Up Sports Training Untuk Meningkatkan Industri Olahraga Berbasis Teknologi Digital
Authors: Dharmadi Made Agus
Published: December 2022

Industri olahraga berbasis teknologi saat ini menjadi arah pengembangan dari Desain Besar Olahraga Nasional yang dicanangkan oleh pemerintah. Oleh karena itu, penelitian ini bertujuan untuk menciptakan befind: start-up sports training untuk meningkatkan industri olahraga berbasis teknologi digital. Penelitian ini merupakan penelitian deskriptif kuantitatif, dengan pengumpulan data menggunakan kuesioner/ angket, wawancara dan studi dokumentasi. Sampel/ responden dalam penelitian ini adalah pelajar dan masyarakat umum dengan rentang usia 16-50 tahun. Sebanyak 171 responden telah mengisi kuesioner analisis kebutuhan pengembangan Start-Up tentang pelatihan olahraga ‘BeFind’. Berdasarkan analisis data yang diperoleh, dapat disimpulkan bahwa; sebagian besar, 84% menyatakan bahwa tujuan berolahraga adalah untuk kebugaran dan kesehatan, sebagian besar 61% responden menyatakan permasalahan yang dialami saat berolahraga adalah sulit mencari informasi terkait pelatihan olahraga. Sebesar 87% menyatakan bersedia mengeluarkan biaya untuk mencapai kebugaran dan kesehatan, dan  sebagian besar 88% bersedia menggunakan media teknologi digital/aplikasi untuk mencari informasi dan berlatih olahraga. Hal ini menunjukan bahwa masyarakat sangat membutuhkan media teknologi digital/aplikasi untuk mencari informasi, konsultasi dan berlatih olahraga terhadap pencapaian kebugaran dan kesehatan bahkan juga prestasi olahraga.
Re-examining Institutionalized Schooling: A New Era in Basic Education Institutions in Kenya
Authors: Mackatiani Caleb , Mackatiani Navin , Imbova Mercy
Published: December 2022

This study examined critical concerns for reconsidering the future of education in Kenya. These are power/authority, school processes and policies, and the curriculum. Schools have developed regulations that have evolved into school cultures, leading to the institutionalization of education. Learners are enslaved due to administrators' expectations based on institutionalization-causing factors. This study aimed to analyze the elements that influence institutionalized education in Kenya. The issue was examined using both qualitative and quantitative methodologies. The study utilized a 384-person sample with a confidence interval of 0.05, a confidence level of 95%, a Z-score of 1.96, and a standard deviation of 0.5. The study indicated that school policies influence the power and authority of institutionalized education. The study discovered that headship authority and power institutionalize schools. Power, policies, and curricula institutionalize the elementary and secondary levels of education. This has spurred disobedience among teachers and students.
STRENGTH PROPERTIES OF ELASTIC DENTAL MATERIALS ON THE BASE OF MODIFIED POLYACRYLATES
Authors:   Lviv Polytechnic National University, Chopyk N. V. , Zemke V. M. ,   Lviv Polytechnic National University
Published: December 2022

A comparative analysis of the strength properties of hydrogel composition and implants made of polymethylmethacrylate was conducted. Based on polyvinylpyrrolidone and 2- hydroxyethyl-methacrylate including additives of hydrophobic monomers a composition for making soft lining have been proposed. The adhesion strength (tension) of elastic materials bond by the method of “shear” and “breakaway” was studied. It was determined that adhesive strength values of hydrogel composition are quite high. It makes possible applying the composition as cover layer for the removable dentures basis.
Muka positif dan muka negatif: analisis novel “Tahajjud Cinta Rania” perspektif Ervin Goffman
Authors:   Universitas Islam Negeri Maulana Malik Ibrahim Malang, Muassomah Muassomah , Fariza Chilmi Laily Sitta ,   Universitas Islam Negeri Maulana Malik Ibrahim Malang, Billah Baedt Giri Mukhoddam ,   Universitas Islam Negeri Maulana Malik Ibrahim Malang
Published: December 2022

Penelitian ini bertujuan untuk mendekskipsikan dan menjabarkan bentuk dan fungsi tuturan muka positif dan muka negatif dalam novel Tahajud Cinta Rania berdasarkan perspektif ErvingGoffman. Metode yang digunakan dalam penelitian ini deskriptif kualitatif dengan sumber data novel berbahasa Indonesia yang bertema romansa dan berbalut religi dengan judul Tahajud Cinta Raniakarya ustadzah Mia Chuz dan ustadz Nasrullah. Data dikumpulkan dengan metode baca dan catat. Tahapan analisis data meliputi reduksi data, penyajian data, dan penarikan kesimpulan. Hasil penelitian ini memperlihatkan bahwa bentuk tuturan muka positif meliputi perhatian, solidaritas, kesekoncoan, memberikan pertanyaan, meminta persetujuan, memberikan tawaran, meminta alasan, gurauan, optimis, dan memberikan hadiah. Sementara bentuk tuturan muka negatif yang tercermin pada kemarahan, meminta maaf, memberikan menghormati, dan menggunakan ketentuan yang bersifat umum. Fungsi muka positif ditunjukkan dengan rasa peduli, saling mengajak pada kebaikan, saling menguatkan, ingin mendapatkan jawaban, mendapatkan hasil terbaik, memberikan pilihan, mendapatkan penjelasan, saking bergurau dan menghibur, yakin, dan memberikan hal special. Sedangkan fungsi muka negatif tertuang ingin mendapatkan keadilan, mendapatkan penerimaan, saling menghormati, dan memperindah keadaan. Penelitian ini menyarankan kajian novel yang sama dalam perspektif yang berbeda, hingga memperkaya hazanah kajian sastra Indonesia. Kata kunci: Goffman, kesantunan bahasa, muka negatif, muka positif