bluuebunny/crossref_metadata_2025 huggingface dataset:
Strategi Pengembangan Aspek Lingkungan di Titik Pandang Panenjoan dengan Berlandaskan Konsep Pariwisata Bertanggung Jawab
Authors: Wibowo Irham Nur Prasetyo
Published: March 2021

Panenjoan is one of the tourist destinations located within the Geopark Ciletuh-Palabuhanratu. This destination is located in the village of Tamanjaya, Ciemas District, Sukabumi Regency, West Java. Since the area was established as part of the Geopark Ciletuh-Palabuhanratu, an increasing number of tourists visit continues to happen every year. Negative e ects can occur if the destination is not ready in accepting such a surge, especially environmental aspects. Therefore, the study aims to formulate a development strategy for Panenjoan view point based on the concept of responsible tourism that focused on environmental aspects. This research uses qualitative research methods with data derived from the results of focused group discussion or FGD, the eld observation, and the study of the literature. Data analysis was done with the SWOT analysis and the results obtained are then elaborated in descriptive. The results obtained from this research is based on a matrix of IFAS and EFAS can note that the position of the internal and external Point of view Panenjoan tend to be weak and threatened with a score each amounting to 2.15 and 2.28. To address and minimize such threats and weaknesses, has drawn up recommendations that focus on environmental aspects of responsible tourism i.e. (1) conserving water aspect consisting of organic mulch-making training, partnership with agencies in the procurement of electronic water meter, increasing public awareness in conservation of water, and the involvement of travelers in the preservation of water. (2) The aspect of using energy e ciently which consists of working with agencies to procure light Light Emitting Diode (LED) as well as in the regular maintenance of electronic tools, and installation of the light sensor. (3) Reducing and managing waste aspect, namely waste management training, digitalization of information contents, procurement of simple recycling facility, and the separating wastes speci cally.
Has Financial Integration of ASEAN and APEC Contributed to Economic Growth?
Authors: Kurihara Yutaka
Published: March 2021

As globalization prevails, financial integration has been ongoing. The movement of globalization has occurred from the 1980s and a lot of attention has been paid to occurred issues from of aspects. This study focuses on whether financial integration in ASEAN and APEC promotes economic growth or not. These areas have attempted to tackle integration and cooperation and to achieve growth. Also, a global financial crisis occurred in the 1990s, and the 2000s made policy makers and business persons aware of potential contagion. Globalization sometimes has caused a contagion of financial crises. On the other hand, cooperation promoted recovery from the damaged economy in some areas. So the pros and cons have been examined, however, a definite answer whether financial integration is correct or not remains unknown. Using available data, empirical analyses are conducted in this study to examine the relationship between financial integration and economic growth. The empirical results show that financial integration has contributed to economic growth in ASEAN, however, this result cannot be applied clearly to APEC. The variety of participating countries in APEC may have affected the result. Moreover, there are some problems to be solved for sound economic growth for these areas.
Estabilidad oxidativa y contenido de compuestos fenólicos durante el almacenamiento del salvado de sorgo (Sorghum bicolor (L.) Moench) extrudido
Authors: Ortiz-Cruz Raquel Alejandra , Ramírez-Wong Benjamín , Sánchez-Machado Dalia Isabel , Ledesma-Osuna Ana Irene , Torres-Chávez Patricia Isabel , Montaño-Leyva Beatriz , López-Cervantes Jaime
Published: March 2021

El salvado de sorgo posee una alta capacidad antioxidante debido a su elevado contenido de compuestos fenólicos. Durante el decorticado del grano para la obtención del salvado, pueden presentarse reacciones de oxidación lipídica que deterioran su calidad. Para evitar esto, se emplean procesos de estabilización como la extrusión. El objetivo de este trabajo fue evaluar los cambios químicos en los compuestos fenólicos y la capacidad antioxidante del salvado de sorgo rojo extrudido. Los salvados de sorgo crudo (SC) y extrudido (SE) se almacenaron durante 42 días para poder evaluar los cambios químicos (índice de peróxidos, pH y ácidos grasos libres), en los compuestos fenólicos, su capacidad antioxidante y la presencia de ácidos fenólicos. El tipo de salvado fue el factor que más afectó los resultados de las evaluaciones químicas. La calidad del SE fue más estable en comparación con la del SC, el cual tuvo cambios significativos de ácidos grasos libres e índice de peróxidos. El contenido de compuestos fenólicos y la capacidad antioxidante de ambos tipos de salvado no se modificaron significativamente (p > 0.05) por efecto del tiempo de almacenamiento, sin embargo, el SE presentó niveles superiores en compuestos fenólicos y capacidad antioxidante que el SC. El proceso de extrusión del salvado de sorgo retarda la oxidación enzimática y mejora la extracción de los compuestos fenólicos.
Understanding the concept of Purgation (Ishal) in Unani Medicine: A Review
Authors: Kouser Hina V , Khan Fatima , Tehseen Ayesha , Nayab Mohd , Ansari Abdul Nasir
Published: March 2021

The theory of humours (akhlat) is one of the fundamental pillars of the Unani System of Medicine (USM). The concept of health and disease depends on the quality (kaifiyat) and quantity (kammiyat) of humour (khilt). Health (sehat) lasts when humours remain in equilibrium and the main determinant of health is the balance in six essential factors (asbab-e-sittah zarooriya). These factors are highly modifiable and deviation in any of them leads to disequilibrium in humours either qualitatively or quantitatively which ultimately manifests in the form of the disease. Elimination (istifragh) of these morbid humours from the body becomes mandatory to treat the diseases or to restore health. One of the effective methods of elimination is purgation (ishal). It is a method by which morbid humours from the body are eliminated through the anal route. Before the elimination of any pathological humour especially in chronic diseases, it is mandatory to make the humour easily eliminable. This process of making the pathological humour eliminable is known as concoction (nuzj). The process of concoction is a regular and continuous process of the tabiyat (mediatrix naturae) of the body. In case of a minor deviation in humour, tabiyat itself eliminates it from the body after concoction. When the causative pathological humours are in abundance or grossly deviated from normalcy, tabiyat needs help from outside the body. This help of tabiyat can be done with some humour specific drugs which are known as concoctive medicines (munzij advia). Once, the humours become eliminable, the process of evacuation can be started. Classical Unani literature and published papers were explored to find the rationale of purgation therapy. Purgation is found to be advisable in the treatment of many chronic diseases. Tabiyat is the ultimate healer in the body and purgation helps it to overcome the diseases.

Keywords: Istifragh; Munzij; Nuzj; Akhlat; Humours; Concoction
Modification of natural hydrocolloid as disintegrant in aceclofenac tablet formulation
Authors: Gupta Vandana , Manigauha Ashish
Published: March 2021

The purpose of present exploration was to modify kappa (k)-Carrageenan, by crosslinking, and assessed it as a tablet disintegrant to strengthen the solubility of the drug (aceclofenac) in tablet formulation. Modified k-Carrageenan was synthesized by reacting it with epichlorhydrin at heterogenous  conditions. The swelling action of the product was investigated in order to optimize reaction circumstances for chemical cross-linking. Best modified k-Carrageenan procured by optimizing the reaction conditions and it was characterized for swelling index, particle size distribution, solubility, viscosity, gel strength and Fourier transform infrared spectroscopy (FTIR). Influence of modified k-Carrageenan on dissolution profile of therapeutic was also investigated along with other evaluation parameters. Modified k-Carrageenan exhibiting significant swelling index which is comparable to that of superdisintegrants. On comparative investigation as a tablet disintegrant by preparing anhydrous dicalcium phosphate tablet, modified k-Carrageenan showed disintegration time less than 20 seconds. Dissolution of aceclofenac (Class II) tablet formulaion utilizing modified k-Carrageenan was comparable with commercially available superdisintegrants. Faster dissolution of the accommodated drug was achieved with modified k-Carrageenan which was comparable with dissolution of the tablet formulation containing other superdisintegrants. The competent concentration of k-Carrageenan was found to be 5-15% as tablet disintegrant. Modified k-Carrageenan might be encouraging tablet disintegrant in fast dissolving formulations and can be worn in direct compression method. Keywords: k-Carageenan. Epichlorhydrin. Aceclofenac. Crosslinking. Superdisintegrant
Evaluation of the Health Impact of the National Diabetes Program in Paraguay
Authors: Rodríguez Patricia Vera , Vera Zully , Maciel Olga , Marin Lupe , Maidana Gladys Mabel , Marin Gina , Marin Gustavo H.
Published: March 2021

The clinical evolution of a diabetic patient is linked to its compliance with non-pharmacological measures such as diet, physical activity, acquiring habits, medical controls and also with its pharmacological treatment.

In different Latin American countries such as the Republic of Paraguay, there are National Programs to provide free support and treatment to the diabetic population that mostly have vulnerable social conditions. However, the impact of these government policies is not routinely evaluated. In order to establish the achievements of a state diabetes program, the present study was carried out.

Methodology: This is a descriptive, cross-sectional study with an analytical stage.

Results: low adherence to non-pharmacological measures such as diet and physical activity was detected. A high percentage of patients were overweight (38%) or obese (46.5%). 75% of the population enrolled in this study did not comply with the program recommendations regarding the time and frequency of physical activities, nor they complied with the minimum 6 daily meals required. Only 37% of the patients had normal levels of glycated hemoglobin and 51.3% of them had pharmacological treatment adherence. Low compliance was observed in relation to regular medical examinations (which were under free coverage by the program) that are transposed in 22% of retinal studies and 60% in 24-hour urine analysis for the early detection of complications such as retinopathy and nephropathy.

Conclusion: Despite the economic and logistical efforts carried out by State programs in order to care of people with diabetes mellitus, data showed a low adherence of patients to the proposed pharmacological and non-pharmacological measures. A personalized follow-up strategy is necessary to improve treatment adherence and to obtain better therapeutic results.

Keywords: Diabetes, adherence, treatment measures, National Program
Sibr (Aloe barbadensis): A Short Description with Unani Approach
Authors: Akhtar Hilal , Akhtar Mohammad Wasi , Khan Mohammad Saad Ahmad , Husain Syed Zeba
Published: March 2021

In many parts of world, there is still a tradition of using herbal drugs to combat various diseases & infections. Sibr is one of the essential components of Unani system of medicine and used by Unani physicians due to it’s a lot of medicinal properties since ancient time. It is commonly called Aloe-vera and belongs to the Lilicaceal family. It is a cactus like herb and grows in hot and arid environment. Unani physicians have been using this drug as a laxative, purgative (phlegm/bile), brain tonic, stomach tonic, liver tonic, emmenogogue, anti-inflammatory, blood purifier, antibacterial, and carminative agent. Hence, this drug having a vital place in Unani system of medicine and text. It is also use to reducing Low density Lipoprotein, increasing High density Lipoprotein, minimizing frost-bite injury, reducing blood glucose level, fighting against Acquired Immuno Deficiency Syndrome (AIDS), allergies, and boosting immune system. This article was designed to lime light the Aloe barbadensis by describing its brief toxicology, contraindications, traditional, therapeutic and others uses.

Keywords: Antibacterial, Aloe barbadensis, Sibr, therapeutic, Unani system of medicine.
Review On Use Of Polymeric Hydrogel For Cartilage Regeneration.
Authors: Jebasurya D. , Arjun Uppuluri Varuna Naga Venkata , T.S. Shanmugarajan
Published: March 2021

The therapy for articular cartilage trauma was a major challenge in the medical field. However due to their 3D cross linking capability and tissue mimicking nature , hydrogel played a crucial role in cartilage regeneration. However, when compared to traditional gels, hydrogels have many distinct properties that make them desirable for several biomedical applications. Firstly, the compact size of the hydrogels enables it to pass through the compact needles and catheters, which is useful for minimally invasive cells and biological deliveries in case of cartilage tissue regeneration. Further, the physical interactions among the polymers also lead to shear thinning behavior that enables the solid-like consistency in case of hydrogel scaffolds without the need for chemical modifications. In general, the polymeric hydrogels thus approaching the ideal characteristics must adhere to the site of the application, relieve traumatic signs, facilitate the faster rate of cartilage regeneration and seek to restore the normal daily activities of the preclinical or clinical subjects. Furthermore, in this review addresses past and current efforts with a brief overview of the highlighted properties for cartilage repair applications of hydrogel scaffolds made from both natural and synthetic polymers. We reviewed the multi scale properties of the hydrogel scaffolds such as mechanical properties and porosity. Moreover, this review focuses primarily on illustrating the characteristics of ideal polymeric hydrogels that are compatible with cartilage repair
A PONDERAÇÃO DE PRINCÍPIOS NO PROCESSO: A COISA JULGADA E OS DIREITOS FUNDAMENTAIS
Authors: Pegado Mário José de Assis
Published: March 2021

A coisa julgada, como direito fundamental insculpido na Constituição, possui a estatura de princípio.Os princípios, diversamente das regras, não possuem caráter absoluto, resolvendo-se por umcódigo binário. São passíveis de ponderação, para que sejam realizados no maior grau possível. Emdeterminadas circunstâncias, a coisa julgada cederá a outro princípio fundamental prevalente,obedecida a necessidade de vir a decisão acompanhada de fundamentação reforçada por sólidabase argumentativa e pela necessidade premente de realização do princípio prevalente, ante adisciplina jurídica constitucional. O objetivo deste trabalho é questionar a intangibilidade absolutada coisa julgada, amoldando a sua disciplina às técnicas de interpretação de normas constitucionais,possibilitando sua eventual superação por meio da técnica da ponderação, diante da realidade do casoconcreto, sem redução de sua força normativa.
O DIREITO DO CONSUMIDOR COMO CONSEQUÊNCIA DA RECONSTRUÇÃO DO DISCURSO CONSTITUCIONAL
Authors: Cruz André Pinheiro
Published: March 2021

Os conceitos de identidade e sujeito constitucional, assim como o debate quanto à reconstrução dodiscurso constitucional e a atribuição de sentidos aos direitos fundamentais, são temas de necessáriaabordagem crítica. A discussão aqui travada é de como essa reflexão pode ser transportada para oentendimento sobre o público e o privado, o que serviu de pano de fundo para a criação do Direitodo Consumidor. Neste artigo, são abordados aspectos técnicos do Código de Defesa do Consumidorbrasileiro, no intuito de reconstrução de sentidos. Afinal, como todo ramo do conhecimento, o direito éum construir, e o seu constante debate e discussão levam ao reconhecimento de identidade do cidadãopara com a regra que lhe rege. Para tanto, são utilizadas teorias de Habermas, Rosenfeld, Lacan, bemcomo levantamentos bibliográficos sobre o Código de Defesa do Consumidor brasileiro.
Apresentação - volume 107, n.2, da Revista de Doutrina e Jurisprudência – RDJ
Authors: Ulhôa Humberto
Published: March 2021

.
PRINCÍPIO DA PRECAUÇÃO: A INCERTEZA COMO PRERROGATIVA DE SEGURANÇA DA CADEIA AGROALIMENTAR
Authors: Silva Layani Ramalho Lopes
Published: March 2021

Existe um quadro acelerado em nosso país de liberações de transgênicos. Esse quadro só é possívelgraças a normas flexíveis de avaliação de risco. A relevância do tema deriva da percepção de que anecessidade dos produtores, atualmente, é a de aumentar o máximo possível a produtividade e reduziros custos. Assim, a implantação dos transgênicos aparece como uma solução para todos os problemas,uma vez que potencializa ganhos e diminui custos. Todavia, é necessário cautela, visto que os avançostecnológicos, indubitavelmente, implicam influências no meio ambiente. Essa cautela se revela aindamais necessária à medida que nos aprofundamos no tema e vemos as diversas posições divergentes desegmentos da sociedade. Há posicionamentos distintos nas áreas da política, da ciência, da economia,entre outras.
A MATERNIDADE DE SUBSTITUIÇÃO E O CONFLITO DE PRESUNÇÃO DE MATERNIDADE CERTA: ESTUDO DE CASOS
Authors: Rocha Pereira Teixeira Caroline
Published: March 2021

O presente artigo tem por objetivo analisar a relatividade da presunção de maternidade certa, conhecida como “mater semper certa est”, no caso de maternidade de substituição. Para tanto, serão demonstradas as mudanças ocorridas na estrutura familiar, como a liberdade de planejamento familiar, estabelecida na Constituição Federal, dentre outras advindas da evolução científica. Posteriormente, conceitua-se a maternidade de substituição, elucidando seus aspectos jurídicos, sob a perspectiva do direito comparado, além de todos os procedimentos médicos necessários. Por fim, será feito um estudo de casos. O primeiro é conhecido como o caso do “Baby M.”, julgado na Suprema Corte de New Jersey, que foi escolhido em razão da discussão jurídica sobre a definição da maternidade, na hipótese de barriga de aluguel. No segundo caso, será falado sobre o registro civil no processo nº 104.323/2009, decidido pelo Conselho Superior da Magistratura de São Paulo, escolhido também com a finalidade de analisar a definição da maternidade, mas, nesse caso, na prática de cessão temporária de útero para gestação de uma criança encomendada por outro casal, seja de forma onerosa ou gratuita.Palavras-chave: Direito Civil. Presunção de maternidade certa. Maternidade de substituição. Estudo de casos. Resolução nº 2013/2013 do Conselho Federal de Medicina.
LEI 12.527, DE 2011 - ANÁLISE DOS MODELOS PARA DIVULGAR A REMUNERAÇÃO DOS AGENTES PÚBLICOS NA INTERNET
Authors: Quintas Fábio Lima , Nascimento Dijeison Tiago Rios
Published: March 2021

O presente artigo se propõe a realizar estudo sobre as formas de aplicação da Lei nº 12.527/2011, também conhecida como Lei de Acesso à Informação, no que se refere à divulgação da remuneração dos agentes estatais de forma individual e nominada na internet. Examinaram-se os modelos adotados em âmbito federal e estadual, abrangendo o Poder Executivo, o Poder Legislativo, o Poder Judiciário, o Ministério Público e o Tribunal de Contas da União. A pesquisa indica que há uma certa uniformidade no tratamento do tema, obstante surjam leituras distintas e pontuais para a implementação dessa obrigação legal de divulgar dados relativos à remuneração de agentes estatais, no exercício de suposta discricionariedade e autonomia do Poder Público.
ADOÇÃO: CONTROVÉRSIAS A RESPEITO DA MODALIDADE INTUITU PERSONAE
Authors: Alves de Lima Ricardo , Marques Braidotti Adrielli
Published: March 2021

Este trabalho visa estudar o instituto da adoção em suas origens, bem como na forma que se encontra na legislação atual e em como é utilizado no Brasil. Para tanto, é feita uma conceituação do instituto, seguida pelo seu desenvolvimento histórico, a fim de demonstrar que a adoção é um instituto que sofreu diversas mudanças ao longo do tempo, tendendo sempre a se amoldar à realidade social na qual estava inserida. Ademais, trabalhará com a principiologia aplicada no instituto da adoção, em especial com o princípio do melhor interesse da criança e do adolescente e com o princípio da afetividade. Analisará, ainda, o procedimento que a adoção segue na vigente legislação brasileira. Por fim, discutirá a modalidade intuitu personae de adoção, analisando a omissão legislativa que a cerca, bem como a possibilidade de analogia com o instituto da tutela. Assim, o presente trabalho se mostra relevante, uma vez que defende que um instituto guiado por laços emocionais não pode permitir que a letra fria da lei sobressaia à afetividade.
UMA DÉCADA DO VIVÊNCIAS E CONVIVÊNCIAS: ACOMPANHAMENTO EM GRUPO DE FAMÍLIAS ADOTANTES
Authors: Campos Niva Maria Vasques , Bohm Carlos Henrique , De Jesus Patrícia Serejo , Dos Santos Anna Cristina Pereira , Santoucy Luiza Barros
Published: March 2021

O Estatuto da Criança e do Adolescente prevê o acompanhamento das famílias adotantes em programa de estágio de convivência conduzido pelas equipes interprofissionais das Varas de Infância e da Juventude (VIJ). O objetivo deste artigo foi apresentar a evolução, as modalidades e os principais resultados de uma década do programa de acompanhamento familiar em grupo, coordenado pela equipe interprofissional da VIJ-DF. Demonstra-se ainda o gradual aumento do número de requerentes acompanhados pelo programa.  Conclui-se que os resultados estão em acordo com o previsto pela legislação, mostrando uma forma eficaz de acompanhar os estágios de convivência, assegurando a proteção integral de crianças e adolescentes e prevenindo novas rupturas e desistências.
O ABANDONO AFETIVO NA JURISPRUDÊNCIA
Authors: Ferreira Fabrício Ramos , Vieira Aliny Modesto Moura
Published: March 2021

Acerca do tema “abandono afetivo”, pode-se dizer que a jurisprudência espelha as conclusões da doutrina? Ao ser mencionado que existe direito à obtenção de indenização por abandono afetivo, tal se vê na prática? O escopo deste trabalho é fazer uma análise da jurisprudência dos Tribunais de Justiça do Distrito Federal e Territórios, do Superior Tribunal de Justiça e do Supremo Tribunal Federal, para compreender como o tema é visto pelas cortes de justiça. A relevância do tema se sobressai na medida em que, com a vigência do Código de Processo Civil, deve haver uma coesão da jurisprudência, daí a importância de seu estudo e conhecimento. Ao final da pesquisa, chega-se a conclusão de que a jurisprudência afasta-se da doutrina, bem como que a maioria dos julgados analisados apontam no sentido da improcedência dos pedidos de indenização, sendo uma das maiores causas de improcedência a prescrição. Foi identificado que a perícia é critério basilar para que se tenha por configurado o nexo de causalidade para fins de caracterização do direito à indenização. Percebeu-se que o pai é o único a integrar o polo passivo da demanda, bem como que as mulheres-juízas são mais tendentes a julgar procedentes os pedidos do que os homens-juízes.
A FINANCEIRIZAÇÃO DO MERCADO IMOBILIÁRIO: REGULAÇÃO COM BASE NA FUNÇÃO SOCIAL DA PROPRIEDADE URBANA
Authors: Ferreira Neto Ermiro
Published: March 2021

Neste artigo, é apresentada uma análise a respeito da relação entre o setor financeiro e o mercado imobiliário sob o ponto de vista da regulação jurídica da propriedade urbana. Tendo como premissa a “financeirização do mercado imobiliário”, são apresentadas as causas e as consequências para esse fenômeno. Após, a função social da propriedade é indicada como o principal elemento de regulação da propriedade urbana. Em razão disso, a legislação cria diversos mecanismos de intervenção na propriedade urbana. Por fim, a tese central é a de que a ordem jurídica brasileira antes incentiva do que afasta a relação entre capital financeiro e imobiliário, bem como dota o Poder Público de instrumentos para regular os respectivos efeitos.
Outcomes of Redo Isolated Tricuspid Valve Surgery After Left-sided Valve Surgery
Authors: yang liang , Zhou Kan , yang yanchen , He Biao-Chuan , chen zerui , tian chennan , huang huanlei
Published: March 2021

Objectives: This study aimed to compare early and long-term outcomes of
redo isolated tricuspid surgery (RITS) after left-sided valve surgery
(LSVS). Methods: We retrospectively reviewed 173 patients underwent RITS
for severe tricuspid regurgitation after previous LSVS from January 1999
to December 2019. Patients were divided into two groups: RITS by median
sternotomy (m-RITS, n = 78) and by totally endoscopic approach (e-RITS,
n = 95). Perioperative outcomes and follow-up results were analyzed.
Results: There were 19 (11%) in-hospital deaths (14.1% in m-RITS and
8.4% in e-RITS, p = 0.234) that decreased from 16.7% (1999–2014) to
6.9% (2015–2019) (p = 0.044). Tricuspid valve replacement [odds
ratio (OR) = 6.778, 95% confidence interval (CI): 1.370–33.549, p =
0.019] and NYHA function class IV (OR = 8.525, 95% CI: 2.153–33.760,
p = 0.002) were independent risk factors of in-hospital mortality. The
overall 1-, 5-year, 10-year, and 15-year survival rates were 97.2%
(95% CI: 94.5–99.9%),80.3% (95% CI: 71.7–88.9%), 59.2% (95% CI:
43.5–75.5%) and 49.3% (95% CI: 27.2–71.4%), respectively.
Conclusion: Patients undergoing redo isolated tricuspid valve surgery
carry a high risk of early mortality. Satisfactory results are
achievable with endoscopic tricuspid valve surgery and repair results in
lower surgical mortality than replacement with acceptable residual
tricuspid regurgitation.
Assessment of Left Atrial Function after ST-Segment Elevation Acute Myocardial Infarction: An Application of Real Time Three-Dimensional Echocardiography
Authors: Miao yuxia , Xu min , Wang yuetao , Xie xiao , Liu fei , Shao xiaoliang
Published: March 2021

Objective: The purpose of this study is to evaluate the changes of LA
size and function by real-time 3D echocardiography (RT-3DE), and provide
a better understanding about their effects on treatment and prognosis.
Methods: Ten Bama miniature pigs were used for modeling STEMI. Images
were obtained by RT-3DE at multiple time points. From the LA volume-time
relation curve, the LA volume (LAV) and functions (storage, channel, and
active emptying) at different phases were calculated. Blood samples were
obtained for measurements of NT-proBNP, creatine kinase-MB(CK-MB) and
cardiac Troponin-I(cTn-I). Results: (1) LAVmax, LAVmin and LAVpre-a were
all increased with time. (2) The LA expansion index was the most
sensitive index of LA functional change. It increased (p< .05
vs. baseline) at the 1st day after STEMI (acute phase), and was
correlated with diastolic function E/E’ (p< .05), as shown by
univariate correlation analysis. (3) On the 28th day after STEMI, the
active emptying percentage of total emptying (AE) showed a continuously
increasing trend (p< .05), and was correlated with VTILVOT
(time-velocity integral of left ventricular outflow tract) (p<
.05). Conclusions: During the acute phase after STEMI, LA volume changed
in order to increase LV preload. After STIMI, the storage function of LA
was the first to change, while active contractile function was
significantly enhanced during subacute phase. With the accurate
measurement of LA function with RT-3DE, our study will help improving
the therapeutic target setting and pharmacologic interventions, which
may enhance the clinical outcomes of STEMI patients.
Analyzing the Dual Space of the Saturated Ideal of a Regular Set and the Local Multiplicities of its Zeros
Authors: Li Xialiang , Niu Wei
Published: March 2021

In this paper, we are concerned with the problem of counting the
multiplicities of a zero-dimensional regular set’s zeros. We generalize
the squarefree decomposition of univariate polynomials to the so-called
pseudo squarefree decomposition of multivariate polynomials, and then
propose an algorithm for decomposing a regular set into a finite number
of simple sets. From the output of this algorithm, the multiplicities of
zeros could be directly read out, and the real solution isolation with
multiplicity can also be easily produced. As a main theoretical result
of this paper, we analyze the structure of dual space of the saturated
ideal generated by a simple set as well as a regular set. Experiments
with a preliminary implementation show the efficiency of our method.
Renal angiomyolipoma with inferior vena cava and right atrium extension in patient with tuberous sclerosis complex: a rare case report and literature review.
Authors: Li mingyao , Geng Wenlei , Wu Weichun
Published: March 2021

Angiomyolipoma(AML) is one of the most common benign renal tumors.
Classical AML is benign, but it can be locally invasive, extending into
perirenal fat, or in rare cases, invading the renal collecting system,
renal vein or inferior vena cava and right atrium. About 10% of
patients clinically diagnosed with renal AML have tuberous sclerosis
complex. Tuberous sclerosis complex can be diagnosed by genetic
diagnosis or clinical manifestation. We report a rare case of a
35-year-old woman who was diagnosed with tuberous sclerosis complex
caused by TSC2 gene mutation, which was characterized by multiple
angiomyolipoma in the right kidney and extended growth to the inferior
vena cava and right atrium. Intracardiac extension is often observed in
the malignant tumor and only seldom seen in benign tumors. Our case
reminds the rare possibility of intracardiac extension in renal AML,
which may potentially result in fatal complications if not appropriately
managed.
Trends in the Utilization of the Pediatric Emergency Department during the COVID-19 Outbreak
Authors: Drewek Rupali , mirea Lucia , Williams Sophia
Published: March 2021

Background: Despite numerous prior interventions to reduce unnecessary
visits to the emergency department (ED), overutilization and
overreliance on EDs continue to negatively impact quality of care and
cost. Objective: Motivated by finding solutions to ED overuse, we
evaluated the effect of COVID19 on pediatric ED utilization,
specifically focusing on patients with pulmonary diagnoses. Methods: A
retrospective study was conducted to review visits to the pediatric ED
at Phoenix Children’s Hospital. The baseline pre-COVID19 period ranged
from 01/01/2016 to 03/14/2019. Post-COVID19 data were collected from
03/15/2020 to 07/31/2020. Study subjects included all patients between
0-18 years of age. Data was collected biweekly for the number of ED
visits, admission to hospital from ED, presenting diagnosis and
pulmonary consults. Results: The average number of biweekly ED visits
decreased significantly from 3437 during baseline to 2061 post-COVID19,
while the percent of hospital admissions increased from 0.14% to 0.18%
(p< 0.01). A significant decrease was also observed in the
biweekly average number of pulmonology consults (527 to 250), and the
percent of pulmonology consults (0.15% to 0.11%), presenting diagnosis
of asthma (130 to 59), tracheostomy (7 to 6), cystic fibrosis (7 to 5),
cough/wheeze (66 to 41) and bronchiolitis/upper and lower respiratory
tract infections (300 to 126). No changes were detected in chronic
respiratory failure, respiratory distress or hypoxemia. Conclusion: Many
factors including telehealth, improved infection control measures,
social responsibility, and fear of getting sick may have played a role
in the reduction in our ED visits during the COVID pandemic.
A Mass and Energy Conservation Analysis of Drift in the CMIP6 Ensemble
Authors: Irving Damien
Published: March 2021

Coupled climate models are prone to ‘drift’ (long-term unforced trends in state variables) due to incomplete spin-up and non-closure of the global mass and energy budgets. Here we assess model drift and the associated conservation of energy, mass and salt in CMIP6 and CMIP5 models. For most models, drift in globally-integrated ocean mass and heat content represents a small but non-negligible fraction of recent historical trends, while drift in atmospheric water vapor is negligible. Model drift tends to be much larger in time-integrated ocean heat and freshwater flux, net top-of-the-atmosphere radiation (netTOA) and moisture flux into the atmosphere (evaporation minus precipitation), indicating a substantial leakage of mass and energy in the simulated climate system. Most models are able to achieve approximate energy budget closure after drift is removed, but ocean mass budget closure eludes a number of models even after de-drifting and none achieve closure of the atmospheric moisture budget. The magnitude of the drift in the CMIP6 ensemble represents an improvement over CMIP5 in some cases (salinity and time-integrated netTOA) but is worse (time-integrated ocean freshwater and atmospheric moisture fluxes) or little changed (ocean heat content, ocean mass and time-integrated ocean heat flux) for others, while closure of the ocean mass and energy budgets after drift removal has improved.
Longitudinal waves in an elastic rod caused by sudden damage to the foundation
Authors: Shatskyi Ivan , Perepichka Vasyl , Vaskovskyi Maksym
Published: March 2021

We study the problem of propagating longitudinal waves in an elastic rod connected to a locally damaged foundation through a thin elastic layer. The motion of the rigid foundation blocks is considered predetermined. We formulated the initial-boundary problem for the Klein?Gordon equation with a discontinuous right-hand side. The nonstationary fields of displacements, velocities, and deformations were investigated by the Laplace integral transformation method. Examples of sudden divergence of fragments of the foundation by a given value and their mutual separation at a constant speed are considered.
Blockchains: An Experiential Accounting Learning Activity
Authors: Lee Lorraine S. , Appelbaum Deniz , Mautz Richard D
Published: March 2021

Organizations such as the AACSB and the Pathways Commission (2012) recommend that accounting curricula include emerging technologies. Yet including emerging technologies represents a challenge for accounting educators due to the complexity and uncertainty associated with such technologies, as well as the rapid pace of technology change and innovation. This paper answers the call by the Pathways Commission (2012) for additional research that is focused on enhancing learning experiences to better reflect current and emerging technologies. Using an experiential learning approach (Butler, Church, and Spencer 2019), we create an interactive learning activity that is focused on bitcoin blockchains and intended to give accounting students a conceptual understanding of blockchain technology and its mechanisms, as well as its implications beyond bitcoins.
Accuracy of 1-Hour Plasma Glucose During the Oral Glucose Tolerance Test in Diagnosis of Type 2 Diabetes in Adults: A Meta-analysis
Authors: Ahuja Vasudha , Aronen Pasi , Pramodkumar T.A. , Looker Helen , Chetrit Angela , Bloigu Aini H. , Juutilainen Auni , Bianchi Cristina , La Sala Lucia , Anjana Ranjit Mohan , Pradeepa Rajendra , Venkatesan Ulagamadesan , Jebarani Sarvanan , Baskar Viswanathan , Fiorentino Teresa Vanessa , Timpel Patrick , DeFronzo Ralph A. , Ceriello Antonio , Del Prato Stefano , Abdul-Ghani Muhammad , Keinänen-Kiukaanniemi Sirkka , Dankner Rachel , Bennett Peter H. , Knowler William C. , Schwarz Peter , Sesti Giorgio , Oka Rie , Mohan Viswanathan , Groop Leif , Tuomilehto Jaakko , Ripatti Samuli , Bergman Michael , Tuomi Tiinamaija
Published: March 2021

OBJECTIVE

One-hour plasma glucose (1-h PG) during the oral glucose tolerance test (OGTT) is an accurate predictor of type 2 diabetes. We performed a meta-analysis to determine the optimum cutoff of 1-h PG for detection of type 2 diabetes using 2-h PG as the gold standard.

RESEARCH DESIGN AND METHODS

We included 15 studies with 35,551 participants from multiple ethnic groups (53.8% Caucasian) and 2,705 newly detected cases of diabetes based on 2-h PG during OGTT. We excluded cases identified only by elevated fasting plasma glucose and/or HbA1c. We determined the optimal 1-h PG threshold and its accuracy at this cutoff for detection of diabetes (2-h PG ≥11.1 mmol/L) using a mixed linear effects regression model with different weights to sensitivity/specificity (2/3, 1/2, and 1/3).

RESULTS

Three cutoffs of 1-h PG, at 10.6 mmol/L, 11.6 mmol/L, and 12.5 mmol/L, had sensitivities of 0.95, 0.92, and 0.87 and specificities of 0.86, 0.91, and 0.94 at weights 2/3, 1/2, and 1/3, respectively. The cutoff of 11.6 mmol/L (95% CI 10.6, 12.6) had a sensitivity of 0.92 (0.87, 0.95), specificity of 0.91 (0.88, 0.93), area under the curve 0.939 (95% confidence region for sensitivity at a given specificity: 0.904, 0.946), and a positive predictive value of 45%.

CONCLUSIONS

The 1-h PG of ≥11.6 mmol/L during OGTT has a good sensitivity and specificity for detecting type 2 diabetes. Prescreening with a diabetes-specific risk calculator to identify high-risk individuals is suggested to decrease the proportion of false-positive cases. Studies including other ethnic groups and assessing complication risk are warranted.
KARAKTERISASI RESERVOIR UNTUK MENENTUKAN PERSEBARAN BATUPASIR PEMBAWA HIDROKARBON MENGGUNAKAN INVERSI SIMULTAN
Authors: Juventa Juventa , Fatkhan Fatkhan
Published: March 2021

Dalam exploitasi hidrokarbon, salah satu tantangan yang paling penting adalah pemetaan persebaran batuan reservoir dan fluida pengisinya. Salah satu metode yang digunakan adalah inversi simultan. Inversi simultan merupakan salah satu teknik inversi seismik yang mengekstraksi data AVO untuk memperoleh nilai impedansi seismik dari data seismik Pre-Stack hingga memperoleh nilai impedansi P dan S serta densitas. Salah satu metode lanjutan yang paling umum dipakai adalah metode Lambda-Mu-Rho (LMR) untuk membatu identifikasi litologi dan fluida resorvoir. Penelitian dilakukan dengan menggunakan data dari Lapangan Nova Scotia, dengan target pada batupasir Formasi Missisauga. Data yang digunakan adalah data sumur L-30 dan B-41 dan data seismik 3D PSTM. Sumur B-41 berada di struktur lebih tinggi dari sumur L-30 namun tidak menghasilkan hidrokarbon. Log Vs dibuat sintetik menggunakan metode Fluid Replacement Modeling dan LMR diturunkan dengan transformasi log Vp, Vs dan densitas. Hasil pemetaan zona target pada kedalaman 2095-2250 ms yaitu dengan menggunakan range cut-off Lambda-Rho 17-22 Gpa*g/cc dan Mu-Rho 20-28 Gpa*g/cc maka didapat peta persebaran batuan reservoir dan hidrokarbon. Hasil interpretasi dari peta sebaran menunjukkan sumur B-41 adalah dry hole karena lapisan batupasir mempunyai nilai Mu-Rho rendah yang diakibatkan lapisan tipis dan perselingan dengan batulempung.
Influence of Electronic Administration on Public Service Delivery among State Agencies in Kenya
Authors: Riany Kenneth Goga
Published: March 2021

E-Administration remains a key E-Government strategy that seeks to ensure the management of the government institutions and organizations if effectively done to enhance effectiveness and proper service delivery. The purpose of this study was to examine the influence of E-Administration on the public service delivery among state agencies in Kenya. The study adopted a descriptive research design to collect data from the target population comprising of 4230 employees within the management cadre at 132 specific government state agencies. Convenient sampling technique was used by the study to sample the respondents within the 132 specific government state agencies. A sampling formula was applied to calculate the sample size of 365 employees and self-developed questionnaires were used to collect data from the sample. Data was analyzed using descriptive and inferential statistics. The study found that E-Administration had a significant and positive influence on public service delivery by the state agencies in Kenya. The study further established that strategy execution had a significant moderating effect on the relationship between E-Administration and public service delivery by the state agencies in Kenya. The study recommended that the government through the state agencies should embrace E-Administration as a way of enhancing public service delivery. The management of state agencies should furthermore embrace strategy execution practices so as to enable success of E-Administration.
An Investigation of NGOs’ Role in Diminishing Poverty in Sindh
Authors: Ali Sikandar , Ali Shah Asif , Khaskhely Mahvish , Khatoon Sahib , Abro Muhammad Ilyas , Latif Danish
Published: March 2021

Pakistan is a South Asian nation, where a significant portion is in the clutches of poverty characterized by a low standard of living as the country ranks 152th in the global poverty index. Pakistan’s government has been very keen on improving people's economic conditions in the region. NGOs are an essential part of civil society functions to fulfil the need for improvement in human development activities. While various NGOs are working in the country to eradicate poverty, but fruits have yet to be reaped. Thus, the main objective of the current study is to investigate efforts of NGO’s intervened projects to bring forth the improvement in the living conditions of people. For data collection, quantitative methodology and structured questionnaire approach have been employed in the present study. Using the proportional distribution approach, a simple random sample of 300 respondents was drawn for this research analysis. The research was conducted keeping in view the poverty and similarity of the taluka’s geographical and physical setups. For data collection, Sanghar’s rural-talukas i-e Sinjhoro, Khipro, and Tando Adam were selected. The findings indicate that people of the Sanghar district were unhappy and pessimistic towards the NGOs' role in raising their standard of living. This shows concerns about their service delivery and support in the targeted geographical areas. Results also revealed that NGOs are unable to make people self-reliant and there is a need for a robust poverty alleviation strategy to lessen the poverty in the region. In conclusion, policy recommendations are provided, and areas of future studies are identified.
Impact of Organizational Commitment on Civil Servants Performance: An Empirical Study of Alauddin Islamic State University of Indonesia
Authors: Syam'un . , Mahfudnurnajamuddin . , Mallongi Syahrir , Ramlawati . , Budiandriani .
Published: March 2021

This study explores the contribution of organizational culture, competence, work motivation to organizational commitment, to organizational commitment and the performance of 220 civil servants who work in the administration section of Alauddin Islamic State University of Indonesia (Makassar). Data were analyzed using analysis of moment structures. The exploratory findings provide evidence that organizational culture and work motivation contribute fully and significantly in increasing organizational commitment, in contrast to competence the results are in opposite directions. In other causality, it was found that culture and organizational commitment significantly contributed to improving employee performance, while low work competence and motivation were not proven to contribute.
Environmental Consequences of Poor Landfill Management
Authors: Osazee Iyenoma ThankGod , Gupta Bhaskar Sen
Published: March 2021

Landfill is a popular method of waste disposal in many countries due to its relatively low of costs of operation. The offensive aspect of the method is improper removal or disposal of the waste, which has resulted in avoidable sicknesses, diseases and preventable deaths. Carbon dioxide and methane are the two main gases emitted from landfill sites; municipal solid waste issue accounts for almost 5% of total greenhouse gas emissions and methane from landfills accounts for 12% of the total quantity of global methane emissions. Landfills can be put to sustainable use by employing it to produce energy from waste whenever is feasible and it has the capacity to generate revenue. Furthermore, many advanced waste treatment technologies have been developed which received commendable attention in developed countries and are evolving in developing countries. Landfill gas-to-energy is viable economically and for control of methane emissions and effective management of time, costs and quality with minimum risks to humans and the environment.
LE « MYTHE » DE L’ADOLESCENCE DANS "LE ROMAN DE L’ADOLESCENT MYOPE" DE MIRCEA ELIADE
Authors: JIȘA Simona
Published: March 2021

The Myth of Adolescence in Mircea Eliade’s Diary of a Short-Sighted Adolescent. The article investigates the origins of this novel, which was published decades after its completion, thus identifying the elements that are specific to the genres of the self (autobiography, journal, Bildungsroman). It analyzes some key terms of Mircea Eliade’s world vision which can be pertinently applied to the Diary of a Short-Sighted Adolescent. The article demonstrates the way in which the young Eliade conceives his relation to the profane time of adolescence (the high school years), as well as to its profane spaces (such as the school, the attic, the library), and how he is able to move towards a sacred spatiality and temporality, both of which are spiritualized through his readings and imaginary. This return ab origo, aiming at a better understanding of the homo saber that Mircea Eliade has become, facilitates the sketching of a literary myth – i.e., that of adolescence.
REZUMAT. « Mitul » adolescenței în Romanul adolescentului miop de Mircea Eliade. Articolul investighează originile acestui roman publicat decenii mai târziu după momentul scrierii, identificându-se elementele specifice genurilor eului (autobiografie, jurnal, Bildungsroman). Se analizează termeni-cheie pentru viziunea lui Mircea Eliade asupra lumii care își găsesc pertinența aplicabilității la Romanul adolescentului miop. Se arată modul în care tânărul Eliade își concepe relația cu timpul « profan » al adolescenței (anii de liceu) și cu spațiile « profane » (școala, mansarda, biblioteca) și cum este capabil să meargă spre o temporalitate și spațialitate sacre, spiritualizate de lecturile și imaginarul său. Această întoarcere ab origo pentru a înțelege mai bine pe acest homo saber care a devenit Mircea Eliade facilitează creionarea unui mit literar, cel al adolescenței.
Cuvinte-cheie: Mircea Eliade, Romanul adolescentului miop, Bildungsroman, sacru și profan, mitul adolescenței