bluuebunny/crossref_metadata_2025 huggingface dataset:
Barriers to treatment-seeking for impairment of vision among elderly persons in a resettlement colony of Delhi: A population-based cross-sectional study
Authors: Vignesh D. , Gupta Noopur , Kalaivani Mani , Goswami Anil Kumar , Nongkynrih Baridalyne , Kumar Gupta Sanjeev
Published: June 2022

Background & objectives:

Uncorrected refractive error and cataract are the two most common causes of impairment of vision among elderly persons, and both are treatable. Treatment-seeking in patients is driven by symptom (decreased vision) rather than any anatomical or physiological measurement. The objective of this study was to evaluate the treatment-seeking behavior and barriers to treatment-seeking among elderly persons with impairment of vision in an urban resettlement colony of New Delhi, India.

Methods:

This community-based, cross-sectional study was conducted among 604 persons aged ≥60 yr selected by the simple random sampling. House-to-house visit was done, and a self-developed pretested semi-structured interview schedule was used to collect socio-demographic information, treatment-seeking behaviour and barriers to treatment-seeking.

Results:

Majority of participants reported impairment of vision (84%); 16.5 per cent of them did not visit any healthcare facility for their vision problem. Lack of felt need (48.1%) was the most common barrier to visiting healthcare facility. Of the 401 participants who gave a history of being prescribed spectacles, 277 (69%) used spectacles. Discomfort, lack of improvement in vision and lack of felt need were the most common reasons cited for non-usage. Among 300 participants who gave a history of cataract, 61 (20.3%) had not undergone cataract surgery. Lack of felt need was the most common barrier to cataract surgery.

Interpretation & conclusions:

A substantial proportion of elderly persons in the urban community have impairment of vision. Lack of felt need was the main reason for not visiting healthcare facility. As quality of spectacles was an important reported deterrent to use of spectacles, provision of appropriate refraction services and low-cost, good quality spectacles would be important.
A systematic review on the prevalence of endometriosis in women
Authors: Moradi Yousef , Shams-Beyranvand Mehran , Khateri Sorour , Gharahjeh Saeedeh , Tehrani Shahrzad , Varse Fatemeh , Tiyuri Amir , Najmi Zahra
Published: June 2022

Background & objectives:

Endometriosis is one of the causes of female infertility, but the prevalence of endometriosis is not exactly known. We conducted a systematic review and meta-analysis to provide an estimate of the prevalence of endometriosis in women considering the stage of disease, diagnostic method, geographical distribution, clinical symptoms and sample size.

Methods:

MEDLINE, Web of Science, Google Scholar, Scopus and Cumulative Index of Nursing and Allied Health were searched to identify peer-reviewed studies published from January 1990 to December 2018 reporting the prevalence of endometriosis. Relevant additional articles were identified from the lists of the retrieved articles. Studies with cross-sectional design were included in the meta-analysis.

Results:

The overall prevalence of endometriosis was 18 per cent [95% confidence interval (CI): 16-20] and the prevalence of endometriosis by stage ranged from two per cent (95% CI: 1-4) for stage 4 to 20 per cent (95% CI: 11-28) for stage 1. The prevalence levels of endometriosis in women with infertility, chronic pelvic pain and asymptomatic were 31 (95% CI: 15-48), 42 (95% CI: 25-58) and 23 per cent (95% CI: 19-26), respectively.

Interpretation & conclusions:

The results of this study showed that the prevalence of endometriosis in developing countries was high. Future studies are needed to explore other factors affecting the prevalence of endometriosis worldwide, which may help develop future prevention programmes.
Retrospective study of the effect of sarcopaenia on post-operative outcomes in patients undergoing thoracic surgery
Authors: Karapınar Kemal , Toptaş Mehmet , Yurt Sibel , Tuna Lale , Akkoc İbrahim
Published: June 2022

Background & objectives:

Sarcopaenia refers to the pathological loss of muscle mass that may be observed in malnutrition, immobility, chronic disease, particularly chronic obstructive pulmonary disease and malignancies. A relationship has been identified between sarcopaenia and thoracic surgery. The aim of the present study was to investigate the relationship between density and area of the psoas major muscle (PSM), the pectoralis major and minor muscles (PEC) and the post-operative morbidity, mortality and survival of patients undergoing anatomic lung resection.

Methods:

A retrospective review of the medical record data of the patients who underwent lung resection was conducted in between 2009 and 2018. The study included patients who underwent upper abdominal computed tomography (CT) for the measurement of PSM and thoracic CT for PEC. The demographic data, laboratory test results, radiological findings and the survival data of the patients were recorded.

Results:

Evaluation was made of 161 patients with available CT data. With the exception of mean PEC density, the PEC parameters (P=0.013-0.026), and PSM density (P=0.015) were significantly lower in the non-survivors than in the survivors. In general, the mean measurements of the PSM and PEC were seen to affect mortality (P=0.001-0.024).

Interpretation & conclusions:

The mean area and density measurements in the PSM, and particularly in the PEC, were determined to be significantly higher in patients who survived after lung cancer surgery, suggesting that sarcopaenia could be a useful predictor of post-operative mortality risk and survival.
Influence of Sociodemographic Variables on Psychological Impact and Resilience among Children Living in Multi Hazard Region
Authors: Rehman Ganie Aasim Ur , Jayakumar Christy , Kasi Sekar
Published: June 2022

Background:

Disasters have a great and lasting impact on children physically and psychologically because of their particular physiological and social developmental stage. Disasters are recognized as potential risk for the overall development of children, and children exposed to disasters require some abilities or protective factors which serve as a shield to buffer the risk. The present study was aimed at studying the role of sociodemographic factors on psychological impact and resilience among children exposed to disasters.

Materials and Methods:

A cross-sectional descriptive research design was used to accomplish the study. The study included 100 out of 502 children, 25 each from four schools from four villages selected randomly of four zones of district Anantnag using multi-stage sampling and systematic sampling. The Children Revised Impact of Events Scale-13 and Connor–Davidson Resilience Scale-25 were used to assess the posttraumatic symptoms and resilience among the children.

Results:

The results showed that children had mild-to-moderate level of posttraumatic symptoms, and majority of the children had intermediate to high resilience. This study provided interesting results that female children were found high on resilience and low on posttraumatic symptoms, which is not usual. Significant differences were found between resilience and gender, education, socioeconomic status, income, and domicile as well. Similarly, differences were found between posttraumatic symptoms and displacement, family type, domicile, and education.

Conclusion:

Flood disasters increase the psychological vulnerability for children. To prevent the potential risks, children need protective factors. The present study highlighted that psychological resilience can be improved by looking and improving the sociodemographic factors and making promising ways of establishing resilience-building strategies to regain the spirit of children and families at individual and community level.
Cotton fiber ball as an unusual cause of vaginal discharge in a 5-year-old child
Authors: Kolalapudi Seetharam Anjaneyulu , Shaik Hafiza , Kolaka Sowri Uma , Konala Subhashini , Alluri Rajtha
Published: June 2022

Vaginal discharge in children can be due to many causes. Foreign body in vagina is an unusual cause. Foul-smelling, blood-stained vaginal discharge should raise the suspicion of foreign body in vagina. Magnetic resonance imaging (MRI), vaginal examination under general anesthesia may detect foreign bodies in vagina. We found a cotton fiber ball in vagina, probably caused by the child's teddy bear as a cause of vaginal discharge in a 5-year-old child. A repeat MRI suggested foreign body in the vagina and vaginal exploration under general anesthesia helped for the removal of cotton fiber ball, which led to complete clearance of the vaginal discharge in the child.
A rare presentation of pseudoepitheliomatous keratotic and micaceous balanitis with malignant transformation
Authors: Nandakishore B , Bhat M Ramesh , Fernandes Sonal , Marla Nisha J.
Published: June 2022

Pseudoepitheliomatous keratotic and micaceous balanitis (PKMB) is a rare nonvenereal penile condition with a risk of malignant transformation. We report a case of PKMB in a 45-year-old male who presented with multiple keratotic growths over his glans penis after circumcision for long-standing phimosis. Histopathology revealed pseudoepitheliomatous hyperplasia and atypical cells. He was successfully treated with wide local excision.
An unusual case of recurrent vaginal discharge
Authors: Malik Meenu , Garg Taru , Chander Ram
Published: June 2022

Abnormal vaginal discharge is common among the females of the reproductive age group. Vulvovaginitis caused by azole-resistant Candida albicans is rare. Recurrent vulvovaginal candidiasis (RVVC) causes significant patient distress and morbidity. The vaginal microflora is a complex micro-ecological environment comprising different microbiological species in variable quantities and relative proportions. Any disturbance in the aforesaid causes vaginitis, for instance, aerobic vaginitis (AV) results from the displacement of healthy vaginal Lactobacillus species with aerobic pathogens. We report AV with RVVC caused by C. albicans resistant to even second generation azoles which has not been previously reported to the best of our knowledge.
Epstein-Barr virus infection presenting as encephalitis in HIV—Phenomenon not seen frequently
Authors: Mahajan Rahul , Anand Kuljeet Singh , Juneja Abhishek , Garg Jyoti
Published: June 2022

Epstein-Barr virus (EBV) infection can rarely present as encephalitis in HIV patients. We report a case of a 22-year-old female patient, diagnosed to have HIV infection 8 years back. She presented with headache and altered behavior for a week and focal fits for 2 days. Neurological examination was unremarkable. Cerebrospinal fluid (CSF) examination revealed lymphocytic pleocytosis with raised protein. EBV was detected in CSF using polymerase chain reaction test. Magnetic resonance imaging of the brain revealed T2/fluid-attenuated inversion recovery hyperintensities involving the left frontal cortex, left thalamus, and right medial temporal cortex. The patient was started on antiviral therapy considering the diagnosis of EBV encephalitis. The patient completely recovered over the next few weeks.
Deuil et mélancolie de Narcisse : Le joli buisson de jeunesse de Jean Froissart (1373)
Authors: Sobczyk Agata
Published: June 2022

Żałoba i melancholia Narcyza: Le joli buisson de jeunesse Jeana Froissarta (1373)

Narcyz ukazuje się jako figura przepojona melancholią zarówno w Metamorfozach Owidiusza, jak i w poezji XVI i XVII wieku. W średniowieczu można dostrzec związek tej postaci z melancholią w różnych jej przedstawieniach. Ale Narcyz, który wydaje się najbardziej melancholijny, to ten, którego Jean Froissart przedstawia w Joli buisson de jeunesse, głęboko modyfikując mit Owidiusza. Badacze uważają, że reprezentuje on tu archetyp kochanka. Autorka artykułu sugeruje jednak, że Froissart wykracza poza sferę miłości i temat miłości dworskiej – nie chodzi już o niedostępność obiektu miłości czy też o jego utratę, ale o jakąkolwiek stratę nieodłącznie związaną z upływem czasu. W tym skojarzeniu narcyzmu z żałobą objawia się nostalgia, która wydaje się charakterystyczna dla twórczości Froissarta, ponieważ jest obecna w różnych formach zarówno w jego Kronikach, jak i w jego dziełach lirycznych.

Mourning and Melancholia of Narcissus: Jean Froissart’s Le joli buisson de jeunesse (1373).
Narcissus appears as imbued with melancholy both in Ovid’s Metamorphoses and in the poetry of the sixteenth and seventeenth centuries. In the Middle Ages, the association between this figure and melancholy can be perceived in its various uses. But the Narcissus who seems the most melancholic is the one that Jean Froissart includes in Joli buisson de jeunesse, profoundly modifying the Ovidian myth. The researchers consider this one to represent the archetype of the lover. However, the author of the paper suggests that Froissart goes beyond the domain of love and the theme of courtly love: it is no longer the question of the inaccessibility of the object, nor exclusively of the loss of the object, but of any loss inherent in the passage of time. The association of narcissism with mourning entails the nostalgia that seems specific to Froissart’s work since it is found, in different forms, both in his Chronicles and in his lyrical work.
Birth of a Tibetan Buddhist Master, Part 2: Auspicious Signs and Events at the Birth of the Seventh Karma pa, Chos grags rgya mtsho (1454–1506)
Authors: Dell Dominik
Published: June 2022

This paper deals with accounts of miraculous and auspicious signs and events as an aspect of the secret level in life stories (rnam thar) of Tibetan Buddhist masters and traces these patterns back to the life story of Buddha Śākyamuni, as well as to Vajrayana symbolism. An annotated translation, analysis, and edition of a so-far untranslated section of the rnam thar of the Seventh Karma pa from the Chos ‘byung mkhas pa’i dga’ ston are provided.
The Conditional State of Primates in Selected Zoological Garden in Nigeria: A Survey
Authors: Johnson Joseph
Published: June 2022

Parasitic diseases often represent a major concern in zoo animals for the high environmental contamination due to the maintenance of animals in confined areas. In wild conditions, animals have some natural resistance against parasitic diseases and there is a state of equilibrium between the parasite and the host and it seldom led to harmful infection unless stressed. The aim of the research work is on the conditional state of primates in selected zoological garden primates in selected Zoological Gardens in Nigeria. Survey method was adapted for this research 87 questionnaires was distributed among staff taking care of the zoological gardens. The findings of this work shows, that captive primates are housed according to their species. From the responses, the nutritional status of the captive primates is moderate, based on their physical appearance, and shows 34 respondents, representing (39.1%) Agreed, 29 respondents, representing (33.3%) strongly agreed that the captive primates are constantly dewormed against parasitic infections, while 20 respondents, representing (4.6%) strongly disagreed. On the accountability of the funds, 36 respondents, representing (41.4%) Agreed, 18 respondents, representing (20.7%) strongly agreed, while 24 respondents, which represents (27.6%) disagreed and 9 representing (10.3%) strongly disagreed based on the data, there is adequate accountability of the funds allocated to zoos.
VLSI Implementation of DENLMS Adaptive Filter for Biomedical Applications
Authors: Venkatesan C. , Thamaraimanalan T. , Latha R.
Published: June 2022

Very Large Scale Integration (VLSI) implementation of the Delayed Error Normalized LMS (DENLMS) adaptive filter using a pipelined architecture is proposed and it can be used for biomedical applications. The proposed pipelined VLSI architecture increases the performance of adaptive filters by lowering the amount of time spent on critical path calculation. When compared to the current Error Normalized Least Mean Square (ENLMS) method for pipelining purposes, the DENLMS technique requires an additional delay element, and because of the delay element, the algorithm functions faster and more effective in low-power applications. The proposed pipelined architecture of the DENLMS filter, on the other hand, improves the efficiency while consuming less power overall. The cell leakage power reduction and total dynamic power reduction obtained by using the DENLMS filter are 31.8% and 33.5%, respectively, although the overall area of the filter has increased by 20.4%.
A Novel Undistorted Image Fusion and DWT Based Compression Model with FPGA Implementation for Medical Applications
Authors: Mohankumar M. , Akilan S. , Hariprasath B. , Ariprasath R. , Dharsan S. Dhanu
Published: June 2022

The usage of a fused image and compressed model in a VLSI implementation is demonstrated. In this study, distortion correction is also considered. In distortion correction models, least-squares estimate is utilized. The technique of picture fusion is widely employed in medical imaging. Many pictures are obtained from various sensors (or) multiple images are captured at different times by one sensor in the image fusion approach. CT scans give useful information on denser tissue with the least amount of distortion. The information obtained from a magnetic resonance imaging (MRI) of soft tissue with significant distortion is useful. The DWT-based image fusion approach employs discrete wavelet transforms, a novel multi-resolution analytic tool. Back mapping expansion polynomial is used to reduce computer complexity. Using 0.18um technology, the suggested VLSI design achieves 218MHz with 1480 logical components.
KURUMSAL YÖNETİM MEKANİZMALARININ ARAŞTIRMA VE GELİŞTİRME GİDERLERİ ÜZERİNDEKİ ETKİSİ: BORSA İSTANBUL ÜZERİNE BİR İNCELEME
Authors: SEVİMLİ ÖRGÜN Gamze
Published: June 2022

Bu çalışmanın amacı kurumsal yönetim mekanizmalarının araştırma ve geliştirme harcamaları üzerindeki etkisini incelemektir. Bu amaç doğrultusunda, 2012-2020 yılları arasında Borsa İstanbul’da faaliyet gösteren 645 firma gözlem yılı verisinden yararlanılan çalışmada, yönetim kurulu büyüklüğü, bağımsız üye oranı, kadın üye oranı, yabancı üye oranı, kurumsal sahiplik, yönetsel sahiplik, yabancı sahiplik ve halka açıklık oranları olmak üzere sekiz farklı kurumsal yönetim göstergesi kullanılmıştır. Ayrıca, araştırma modelinde aktif kârlılığı, piyasa değeri/defter değeri, borçlanma oranı, firma büyüklüğü ve firma yaşı kontrol değişkenleri olarak ilave edilmiştir. Yapılan ampirik analizler neticesinde, yönetim kurulu büyüklüğü ile araştırma ve geliştirme giderleri arasında negatif ve istatistiksel olarak anlamlı bir ilişki elde edilirken; kontrol değişkeni olarak kullanılan aktif karlılığı, borçlanma oranı ve firma büyüklüğü ile araştırma ve geliştirme giderleri arasında ise pozitif yönlü ve istatistiksel olarak anlamlı ilişkiler tespit edilmiştir.
Análisis de hashtags en Twitter: uso estratégico de plataformas de #Verificado19s tras los sismos de 2017 en México
Authors:   ITESO  –  Universidad Jesuita de Guadalajara, México, Flores Mérida Antony
Published: June 2022

El presente trabajo propone una forma de analizar los hashtags utilizados en Twitter en el marco de campañas de acción colectiva digitalmente mediada. Para ello, se exploran los mensajes publicados con el hashtag #Verificado19s en esa plataforma tras los terremotos ocurridos en septiembre de 2017 en México. Se propone que los actores colectivos llevan a cabo un uso estratégico del hashtag y que este se corresponde con el programa de acción de su campaña. Para explorar esta implicación, analizamos las frecuencias, interacciones y clasificamos los hashtags presentes en los mensajes de #Verificado19s y observamos que los usos se relacionan con las necesidades materiales identificadas por el actor colectivo, aunque también se identificaron usos emergentes distintos a los propuestos por la organización. La investigación propone una forma de explorar los hashtags como unidad de análisis con miras a identificar configuraciones del uso de los mismos en redes sociodigitales.
Participación y conversación política en YouTube: #Ayotzinapa, #MichaelBrown y #BlackLivesMatter
Authors:   Tecnológico de Monterrey, México, Castillo-González María Concepción , Martín-del-Campo Alejandro ,   Tecnológico de Monterrey, México, Martínez-López Carmen ,   Tecnológico de Monterrey, México
Published: June 2022

La plataformización de la web transformó la organización de las prácticas sociales, entre ellas las que responden a la violación de los derechos humanos de grupos marginados. A través de un estudio comparado entre protestas sociales que surgieron en 2014 por el abuso policial en contra de jóvenes excluidos de la esfera pública –la desaparición de los 43 estudiantes de Ayotzinapa en México y el asesinato de Michael Brown en Estados Unidos; que engrosó las demandas del movimiento Black Lives Matter– se pretende contribuir a la comprensión de las dinámicas de participación ciudadana que, como conversaciones políticas, se materializan en la plataforma YouTube. Se utilizaron diferentes métodos digitales para el análisis de un corpus de 1,451 vídeos que se subieron durante el primer año de las manifestaciones. Una parte del estudio propone un Índice de participación con base en los comentarios para intentar escapar de la lógica transaccional de la plataforma expuesta en las vistas. Otra parte, indaga en el tipo de actores y en las formas en las que se articuló la protesta. Los resultados muestran que las métricas convencionales invisibilizan actores y redes de participación que se articulan en las movilizaciones contemporáneas.
Cuerpos datificados. Los datos cuir de la comunidad Ballroom latinoamericana
Authors:   Universidad Iberoamericana Ciudad de México,  México, Nivardo Trejo Olvera Luis
Published: June 2022

Este trabajo se enmarca en los estudios de small data (Rogers, 2013) para indagar los efectos y la composición de los datos cuir que realizan en coproducción con las plataformas y los algoritmos las personas de la comunidad Ballroom en Latinoamérica. Reviso el caso de la escena mexicana bajo la etiqueta #ballroommexicano en la plataforma socio-digital de Instagram. Propongo la categoría de cuerpos datificados para hacer inteligible el proceso de datificación (Díaz, 2018) que experimentan los cuerpos que hacen Vogue y la manera en que estas trazas digitales terminan por encarnarse y producir la subjetividad de las personas. Como método realizo un acoplamiento entre herramientas basadas en el uso de software para procesamiento y análisis de imágenes, texto y geolocalizaciones (Rodríguez-Cano, 2021; Sued, 2021) y la etnografía multisituada (Marcus, 1995; Pink, 2019) tanto en la plataforma como en prácticas públicas de Vogue y batallas en Balls. Apoyo la interpretación y análisis con información recabada en entrevistas de corte feminista (Davis y Craven, 2016) a miembrxs de la comunidad de las escenas de Querétaro, CDMX y Bogotá. Para el abordaje teórico empleo teoría crítica feminista (D’Ignazio y Klein (2020) y queer (Guyan, 2022) de datos. Finalmente, establezco conclusiones sobre la composición de los datos cuir, el impacto de los cuerpos datificados en la misma comunidad que los coproduce y los beneficios y riesgos en su manejo.
Innovación metodológica para el estudio de la plataformización
Authors:   UNAM, México, Elisa Sued Gabriela , Lugo Nohemí ,   Tecnológico de Monterrey ,  México
Published: June 2022

En este número podemos observar el empleo de métodos digitales desde perspectivas latinoamericanas que apuestan por la imaginación metodológica (Mills, 2003) y la innovación y apropiación de métodos y herramientas. Este número de Virtualis presenta una producción científica pujante y contemporánea, crítica y consciente de cómo los estudios sobre activismo ciudadano, las conversaciones públicas y las expresiones culturales son atravesadas por las lógicas de las plataformas. Destacan artículos que son críticos y reflexivos hacia los mismos métodos y tratan de ampliarlos, sobre todo desde la postura epistemológica desde la cual se utilizan. Estas investigaciones conjuntan herramientas metodológicas desde una perspectiva que supera la oposición binaria entre lo cuantitativo y lo cualitativo o, lo distante y lo cercano (Moretti, 2016). Estamos seguras de que la coincidencia temática, pero también las diversidades metodológicas, de perspectiva y objeto de estudio, dan cuenta de la mirada crítica y dinámica de la investigación en la región. Esperamos que el número aporte tanto a las reflexiones y cuestionamientos sobre la plataformización así como al repertorio de recursos metodológicos para sus investigaciones futuras.
Hand Washing Practices Among Nurses Working in Covid-19 Ward of Hospital
Authors: Khan Irfan , Khan Jubaid , . Jyoti , Gupta Jyoti , Bajwan Deepika
Published: June 2022

Aim: To assess handwashing practices among nurses working in COVID-19 Ward in Selected hospital of Greater Noida, Uttar Pradesh. Method: The research design selected for study was descriptive research design. The study was conducted in GIMS hospital, Uttar Pradesh. Total sample comprises of 40 staff Nurses. The instrument to generate the necessary data was checklist for assessing the knowledge of Staff Nurses regarding hand washing practices in COVID-19 ward. Results: out of 42 nurses who were working in COVID-19 ward, 24 (57.14%) were doing good practice and 18 (42.85%) having adequate practice of hand washing and none of them had poor practice for hand washing. Conclusion: The result of the study reflects that Most of the Nurses has good practice regarding hand washing in COVID-19 ward.
НАУЧНЫЕ ОСНОВЫ ИСПОЛЬЗОВАНИЯ САЛИЦИЛАТОВ В АДАПТИВНЫХ ТЕХНОЛОГИЯХ ВОЗДЕЛЫВАНИЯ ЯРОВОГО ЯЧМЕНЯ
Authors:   Institute of Biophysics and Cell Engineering, Pashkevich Lyubov V. , Kabashnikova Liudmila F. ,   Institute of Biophysics and Cell Engineering
Published: June 2022

The article scientifically substantiates the use of an exogenous plant metabolite, salicylic acid (SA), as an inducer of nonspecific acquired resistance in spring barley plants. Under a greenhouse experiment, a positive effect of a protective and stimulating composition based on salicylate on the parameters of growth and development of spring barley plants infected with the fungus B. sorokiniana, and the degree of their infection with a fungal disease - dark brown spotting, was revealed. Under field conditions, the stimulating effect of SA and phenyl salicylate on growth processes, the content of photosynthetic pigments in the leaf, the activity of lipid peroxidation and peroxidase in plant cells was shown. An increase in the overall resistance of spring barley plants in crops to unfavorable environmental factors, including phytopathogens, was established, which ultimately ensured the formation of a crop at the level of the standard fungicide Adexar with an increase of 4-5 centners for hectare compared to the untreated control. On the basis of the results obtained, the immunomodulatory drug “Immunakt-SA” was developed, which is a composition of SA and a water-soluble polymer VSP-3. The use of the drug ensures stable yields of barley grain at the level of standard chemical fungicides, which in the future will significantly reduce the use of expensive chemicals for plant protection and the chemical load on the environment.
PROBLEMS OF ECOLOGY OF ANCIENT GREECE
Authors:   International Sakharov Environmental Institute, Belarusian State University, Kozlenko A. V.
Published: June 2022

The article deals with the problems of ecology of ancient Greece. Based on the data of written sources, as well as the results of paleoclimatic studies, the author comes to the conclusion that the climate in Greece of the classical era was minimally different from the modern one, but the ecological situation was somewhat different. With a large population and developed agriculture, signs of decline gradually began to appear, which included increasing soil erosion, especially on the lower slopes of the hills, as well as waterlogging of low-lying land areas. These processes were aggravated by the uncontrolled development of small-scale cattle breeding and the thoughtless destruction of woody vegetation. In the end, these processes brought the country to the brink of an ecological catastrophe and served as one of the reasons for the decline of ancient civilization.
NEW LITERACY FOR SUSTAINABLE DEVELOPMENT
Authors:   Peoples’ Friendship University of Russia (RUDN University), Ermakov D. S. , Sokolova L. I. ,   Peoples’ Friendship University of Russia (RUDN University), Ermakov A. S. ,   Peoples’ Friendship University of Russia (RUDN University)
Published: June 2022

Among “new literacies” that are necessary for the modern person to be preadopted to life in a rapidly changing world, the authors propose “sustainable development literacy”. The article presents data of empirical studies on the assessment of the degree of study of the main problems of sustainable development in educational organizations of various types and levels, as well as the application of appropriate pedagogical technologies (both in the Russian Federation and in foreign countries).
INTERDISCIPLINARITY IN THE TEACHING OF PHYSICS AS A FACTOR OF STRENGTHENING THE ENVIRONMENTAL COMPONENT IN THE PREPARATION OF BACHELORS
Authors:   International Sakharov Environmental Institute, Belarusian State University, Malishevskiy V. F. , Lucevich A. A. ,   International Sakharov Environmental Institute, Belarusian State University
Published: June 2022

The interdisciplinary approach to the organizational and methodological support of the educational process is a reflection of the integration processes in the educational system of higher education. It is typical for almost all academic disciplines of the natural science profile, including physics. This is due to the fact that physical concepts, laws, theories and principles play a decisive role in most sections of natural science. They play an important role in the formation of a scientific worldview and are the foundation for mastering the information contained in special disciplines, for which today the strengthening of the environmental component is relevant.
EDUCATION FOR SUSTAINABLE DEVELOPMENT AS DIRECTION FOR IMPROVEMENT TEACHER’S THROUGH ENVIROMENTAL COMPETENCE
Authors:   International Sakharov Environmental Institute, Belarusian State University, Morozova K. V. , Olevskaya I. Z. ,   International Sakharov Environmental Institute, Belarusian State University
Published: June 2022

The article examines issues related to the urgent problem of our time - education for sustainable development. This article discloses prerequisites for the emergence of the concept of “education for sustainable development” and its connection with the idea of sustainable development, which, in turn, contributes to the development of education in the XXI century. The existing real situation in the educational space is shown. As a result, priority tasks are proposed to address the identified problems. This article proved that it is necessary to reorienting towards the formation of the environmental teachers competence. Thus, education for sustainable development is viewed as direction for the improvement of teacher’s environmental competence.
SPECIAL STUDENT HEALTH DIARY EDUCATIONAL DEPARTMENT AS A MEANS OF DEVELOPMENT ECOLOGICAL CULTURE PERSONALITY
Authors:   International Sakharov Environmental Institute, Belarusian State University, Onishchuk O. N. , Krutalevich M. M. ,   International Sakharov Environmental Institute, Belarusian State University, Hryshanovich N. A. ,   International Sakharov Environmental Institute, Belarusian State University, Symanovich P. G. ,   International Sakharov Environmental Institute, Belarusian State University
Published: June 2022

For the full development of the ecological culture of the students’ personality, it is necessary to realize the importance of their health status and the possibility of improving it by using appropriate physical exercises aimed at correcting existing pathologies and increasing the adaptation of the body. The developed «Health Diary» of students of the special educational department allows you to focus on these aspects, and its systematic filling and implementation of individual recommendations will contribute to the development of the environmental culture of the students personality.
FEATURES OF 21ST CENTURY SKILLS FORMATION IN DISTANT LEARNING AT EFL LESSONS
Authors:   International Sakharov Environmental Institute, Belarusian State University, Belyaeva T. V. , Nikitina L. N. ,   International Sakharov Environmental Institute, Belarusian State University, Levdanskaya N. M. ,   International Sakharov Environmental Institute, Belarusian State University
Published: June 2022

The ever-changing realities of the modern world with the abundance and importance of information, information resources and new technologies, set new goals for education. The skills of the 21st century are necessary for future professionals to be in demand and to move forward on the career ladder, be capable of personal growth. The article examines the concept of “21st century skills”, the classification of skills is given, and each skill group is described in detail. Particular attention is paid to distant learning at EFL lessons. Using different forms of distance learning in working with students opens up new opportunities for learning, professional growth and self-expression.
STUDENTS’ MOTIVATION WHEN USING INTERACTIVE PEDAGOGICAL TECHNOLOGIES IN THE CONDITIONS OF DISTANCE WORK
Authors:   International Sakharov Environmental Institute, Belarusian State University, Dovgulevich N. N. , Gritsai N. A. ,   International Sakharov Environmental Institute, Belarusian State University, Shmatova A. A. ,   Belarusian State Medical University
Published: June 2022

The report considers the issue of motivational possibilities of using interactive pedagogical technologies within the conditions of distance foreign language teaching for students and master course students of non-linguistic specialties. Using the example of a virtual tour, an interactive whiteboard, and case-studies, the possibilities of new approaches are considered, and their advantages and disadvantages are considered.
PROSPECTS AND PROBLEMS OF TEACHING A FOREIGN LANGUAGE FOR STUDENTS OF NON-LINGUISTIC SPECIALTIES IN HIGHER EDUCATION INSTITUTIONS
Authors:   International Sakharov Environmental Institute, Belarusian State University, Kachan I. M. , Kushner P. S. ,   International Sakharov Environmental Institute, Belarusian State University
Published: June 2022

The article discusses problems and prospects while teaching foreign languages, including a second foreign language, in non-linguistic universities, as well as its specificity and importance in further professional activity.
ANALYSIS OF THE MORBIDITY OF THE POPULATION OF THE GRODNO REGION WITH DISEASES OF THE BLOOD CIRCULATION SYSTEM
Authors:   International Sakharov Environmental Institute, Belarusian State University, Alexandrova А. S. , Puhteeva I. V. ,   International Sakharov Environmental Institute, Belarusian State University
Published: June 2022

The results of the study indicate a pronounced increase in the incidence of the circulatory system in the Grodno region during 2016-20, which have a steady upward trend (R2 = 0.9). The average annual rate of general morbidity in the circulatory system was 30,422.34 per 100 thousand of the population, and the primary rate was 2838.16 per 100 thousand of the population. During 2016-20, the BSC in the adult population of the Grodno region increased by 18.6%.
THE RELATIONSHIP OF POLYMORPHIC VARIANTS OF ESTROGEN RECEPTOR GENES WITH THE DEVELOPMENT OF OSTEOPOROSIS IN THE BELARUSIAN POPULATION
Authors:   International Sakharov Environmental Institute, Belarusian State University, Gurskaya N. A. , Kobets K. V. ,   International Sakharov Environmental Institute, Belarusian State University
Published: June 2022

A violation of the hormonal balance is considered one of the factors affecting the development of osteoporosis (OP). The study of the molecular and genetic aspects of this fact will allow us to select a more effective course of OP therapy in the future. Sex hormones, as activators of the expression of a number of genes that regulate bone metabolism, act indirectly through specific receptors. We considered polymorphic variants of the estrogen receptor genes ESR1 and ESR2, encoding the a and в subunits of the estrogen receptor, respectively. Among the studied polymorphic variants of ESR1 (rs9340799, rs2234693, rs1801132) and ESR2 (rs3020444), we identified an association of the T/T genotype of the ESR1 (PvuII) rs2234693 gene with the risk of developing OP (p=0.026) in the Belarusian population.
REGULATORY, ANTIOXIDATIVE AND HEPATOPROTECTIVE EFFECTS OF PLANT POLYPHENOLS AND THEIR NANOSTRUCTURED COMPLEXES
Authors:   Yanka Kupala State University of Grodno, Zavodnik I. B. , Lapshina E. A. ,   Yanka Kupala State University of Grodno, Ilyich T. V. ,   Yanka Kupala State University of Grodno, Veiko A. G. ,   Yanka Kupala State University of Grodno, Kovalenia T. A. ,   Yanka Kupala State University of Grodno, Buko V. U. ,   Yanka Kupala State University of Grodno
Published: June 2022

Flavonoids, secondary plant metabolites, demonstrate a wide range of biological and pharmacological activities. In our experiment, flavonoids and their complexes with cyclodextrins (10—100 gM) dose-dependently prevented lipid peroxidation of erythrocyte and mitochondrial membranes, inhibited oxidation of reduced glutathione, and modulated the proapoptotic process of the mitochondrial permeability transition pores formation, that depends on flavonoid lipophilicity and structures. Generation of maps of the electron density distribution in the quercetin molecule and the quercetin semiquinone radical shows that the active electronic orbitals of quercetin and its semiquinone radical are delocalized along the phenolic rings, which, in the case of a radical, increases radical stability. The quercetin-hydroxypropyl-e-cyclodextrin complex proved to be a more effective antioxidant.
FEATURES OF RHIZOGENESIS OF REGENERANTS PRUNUS SERRULATA v. SHIROFUGEN IN CULTURE IN VITRO AND EX VITRO
Authors:   International Sakharov Environmental Institute, Belarusian State University, Krasinskaya T. A. , Lukyanenko N. O. ,   International Sakharov Environmental Institute, Belarusian State University
Published: June 2022

The aim of the work was to determine the rhysogenesis activity of regenerants of Prunus serrulata v. Shirofugen under ex vitro and in vitro conditions using sorbents (activated carbon and the commercial substance «Polypham») in the nutrient mediums. The addition of sorbents to the MS culture medium contributes to an increase in the rate of rooted plants to 100.0% (with activated carbon) and active root growth (the average root length is 4.1 cm when using activated carbon and «Polypham» consisting of hydrolyzed lysine. The callus on the plants is not observed on the nutrient medium with activated carbon. Plants after ex vitro rhysogenesis adaptate more quickly to the new conditions, experiencing physiological stress, at the rooting stage and not at the adaptation stage, as is observed in plants which have in vitro rhysogenesis.
FEATURES OF COMPLICATIONS OF THE PERIOD OF PREGNANCY AND POSTNATAL CONDITIONS
Authors:   International Sakharov Environmental Institute, Belarusian State University, Nechaeva Y. V. , Kozelko N. А. ,   International Sakharov Environmental Institute, Belarusian State University
Published: June 2022

The results of the study showed that among women attending the antenatal clinic “Borisov Central District Hospital”, urinary tract infections (26.9-32.3%) are the most frequently recorded . Anemia (16.3-18.2%) and venous complications (8.5-14.1%) are often recorded. Least of all of the considered complications in the third trimester is diabetes mellitus (5.2-5.4%). Bleeding in the follow-up and postpartum period for 2016-20 was 11.7% of cases. As a result of the analysis of the dynamics of the health status of women registered with the dispensary in the residential complex “Borisovskaya CRH” for the period from 2016-20, it was found that the dynamics of complications during pregnancy and the postpartum period is characterized by a pronounced steady downward trend (R2> 0.7).
A PERSPECTIVE APPROACH TO THE TREATMENT OF DISEASES CAUSED BY TISSUE FIBROSIS USING THE SECRETOME OF MESENCHYMAL STEM CELLS
Authors:   International Sakharov Environmental Institute, Belarusian State University, Rafalskaya A. V.
Published: June 2022

In this article the problems of pathological differentiation of myofibroblasts, leading to idiopathic pulmonary fibrosis are highlighted. Among the modern methods of therapy, special attention is paid to the cellular approach ,in particular, the use of mesenchymal stem cells. A method of influencing the process of scarring of lung tissue using the secretome of mesenchymal stem cells with properties for medical and therapeutic use was proposed.
MOLECULAR MODELING OF PAR-1 COMPLEXES OF HUMAN RECEPTORS WITH THE VORAPAXAR MOLECULE
Authors:   International Sakharov Environmental Institute, Belarusian State University, Sinyak A. D. , Bakunovich A. V. ,   International Sakharov Environmental Institute, Belarusian State University
Published: June 2022

Vorapaxar (SCH 530348) is a synthetic analogue of the natural substance himbacin, the first representative of a new class of antiplatelet antagonists of the protease-activated receptor (PAR-1) of thrombin.
RETROSPECTIVE ANALYSIS OF THE INCIDENCE OF CERVICAL CANCER IN THE POPULATION IN THE REPUBLIC OF BELARUS
Authors:   International Sakharov Environmental Institute, Belarusian State University, Snorko T. A. , Stelmakh V. A. ,   International Sakharov Environmental Institute, Belarusian State University
Published: June 2022

A retrospective analysis of the dynamics of epidemiological indicators characterizing morbidity and mortality in the Republic of Belarus due to cervical cancer for the period 2009-17 is analyzed according to statistical collections of Health Care. The main trends in the development of this disease have been identified.
QUANTUM CHEMICAL ANALYSIS OF THE SORPTION INTERACTION BETWEEN PSORALENE AND CARBON DIOXIDE (II)
Authors:   International Sakharov Environmental Institute, Belarusian State University, Cheplya V. S. , Shahab S. N. ,   International Sakharov Environmental Institute, Belarusian State University
Published: June 2022

In this paper, the adsorption properties of psoralen in the interaction with CO with the help of the density functional theory (DFT theory level: wB97XD/6-31G*) in a water solvent are investigated. Definitely unrelated interaction of psoralen and CO by electronic properties such as ENOMO and ELUMO, energy gap between HOMO and LUMO, global hardness.
IMPERATIVE OF SELF-VALUE FOR THE REPRESENTATIVES OF LIFE
Authors:   Shupyk National Medical University of Postgraduate Education, Pustovit S. V.
Published: June 2022

The article considers the theoretical prerequisites and foundations for the formation of the imperative of selfvalue of representatives of life in the context of modern environmental ethics. It is concluded that all subjects of life have intrinsic value, and the goal of the new ecological ethics is survival, the preservation of life in its various forms based on the recognition of their intrinsic value. The deontology of I. Kant, the ethics of intersubjectivity of J. Habermas, the principle of responsibility of G. Jonas, the concept of holistic ethics and the common world of all living beings of K.-M. Meyer-Abich are considered as theoretical foundations of self-value imperative.
Skin Cancer and Solar Knowledge Level of Seasonal Agricultural Women Workers
Authors: KARTAL Mert , KARAKAŞ Neşe
Published: June 2022

Introduction: Although the ultraviolet rays are the most significant factors in the formation of skin cancer, the harmful effect of the sun cause various skin diseases. Seasonal agricultural workers constitute the main labor force of the agricultural sector in Turkey. The aim of the study to determine the skin cancer and solar knowledge of the seasonal agricultural women workers. Material and Method: 154 seasonal agricultural women workers were included in the descriptive study. The questionnaire examining the Skin Cancer and Solar Knowledge Scale and the socio-demographic aspects of the participants was applied through face-to-face survey and data were collected accordingly. Statistical Package for the Social Sciences software was used in the analysis of data. Results: It was observed that the majority of the participants were between 18-24 years old and they have very limited knowledge of skin cancer and solar exposure. In addition, it was ascertained that the level of knowledge decreases when the age of women increases.The level of knowing the risk factors of skin cancer wasfound to be higher in women having a high school education or higher in comparison to the women who graduated from primary school. It was concluded that the level of knowledge of women living in the province is higher than the women residing in the countryside. Conclusion: Since the seasonal agricultural workers are included in the risk group in terms of skin cancer, we hereby recommend organizing training to raise the knowledge levels and starting the periodic implementation of cancer screening and monitoring programs.
Kết quả bước đầu điều trị ung thư buồng trứng trong thai kỳ tại Bệnh viện Phụ sản Trung ương
Authors: Phạm Trí Hiếu , Lê Thị Thu Hương , Nguyễn Văn Thắng , Nguyễn Thị Thùy Dung
Published: June 2022

Mục tiêu: Đánh giá kết quả phẫu thuật, điều trị hóa chất và kết cục thai kỳ của những thai phụ mắc ung thư buồng trứng (UTBT) tại Bệnh viện Phụ sản Trung ương (BVPSTƯ).

Đối tượng và phương pháp nghiên cứu: Tất cả các thai phụ mới mắc UTBT nguyên phát, được phẫu thuật và hóa trị tại BVPSTƯ, từ tháng 10/2019 đến tháng 11/2021. Mô tả chùm ca bệnh hồi cứu.

Kết quả nghiên cứu: Có tất cả 8 thai phụ độ tuổi trung bình 27,3 ± 6,3, phẫu thuật cắt buồng trứng hoặc phần phụ tại thời điểm từ 13 – 22 tuần. Chẩn đoán ung thư giai đoạn I theo FIGO, gồm 4 ung thư biểu mô (UTBM) và 4 u tế bào mầm. 8 thai phụ được điều trị hóa chất hầu hết gặp các biến cố nhẹ; trừ 3 thai phụ điều trị Bleomycin – Etoposid – Cisplatin (BEP) xuất hiện thai chậm phát triển trong tử cung (CPTTTC) phải mổ lấy thai (MLT) vì thai suy. 5 thai phụ còn lại đều kết thúc thai kỳ đủ tháng với cân nặng sơ sinh và Apgar tốt.

Kết luận: Phẫu thuật cắt bỏ khối u và hóa trị đối với thai phụ mắc UTBT mang lại kết quả khả quan cho cả mẹ và con.
Điều trị u nguyên bào nuôi nguy cơ thấp kháng Methotrexate bằng phác đồ đơn hóa trị liệu Actinomycin D 5 ngày
Authors: Nguyễn Hà Bảo Vân , Nguyễn Văn Thắng , Lê Thị Thu Hương , Đoàn Thị Hảo
Published: June 2022

Mục tiêu: Các yếu tố lâm sàng, cận lâm sàng có ảnh hưởng đến kết quả điều trị của nhóm bệnh nhân u nguyên bào nuôi nguy cơ thấp kháng Methotrexate (MTX) điều trị bằng phác đồ đơn hóa trị liệu Actinomycin D (ACTD) 5 ngày. Đối tượng và phương pháp nghiên cứu: 40 bệnh nhân u nguyên bào nuôi nguy cơ thấp kháng MTX điều trị bằng ACTD 5 ngày tại Bệnh viện Phụ Sản Trung ương (BVPSTW) từ tháng 01/2019 - 10/2021.

Phương pháp nghiên cứu: Hồi cứu mô tả cắt ngang không đối chứng dựa trên hồ sơ bệnh án của Bệnh viện Phụ Sản Trung ương.

Kết quả: Tỷ lệ thành công chung là 85%, đặc biệt với nhóm bệnh nhân có nồng độ βhCG trước khi đổi phác đồ điều trị ≤ 300IU/l thì tỷ lệ khỏi bệnh đạt tới 91,2% với p = 0,033. Sự khác biệt có ý nghĩa thống kê với OR = 10,33 (CI 95%: 1,44 - 75,69). Điểm FIGO tại thời điểm chẩn đoán bệnh cũng góp phần tiên lượng khả năng đáp ứng điều trị. Từ 0-2 điểm, tỷ lệ kháng thuốc là 0%. Khả năng khỏi bệnh của nhóm có điểm FIGO từ 0-2 điểm lớn gấp 1,46 lần nhóm bệnh nhân từ 3 điểm trở lên. Sự khác biệt có ý nghĩa thống kê với p=0,001. Có 4 tác dụng không mong muốn chính (ADR) là nôn, viêm miệng, hạ bạch cầu, tăng men gan tuy nhiên tỷ lệ ghi nhận các tác dụng này trên lâm sàng không đáng kể và mức độ nhẹ.

Kết luận: Phác đồ Actinomycin D 5 ngày là phác đồ hiệu quả, an toàn trong điều trị nhóm bệnh nhân u nguyên bào nuôi nguy cơ thấp kháng Methotrexate có nồng độ βhCG tại thời điểm chuyển phác đồ điều trị ≤ 300 IU/l và điểm FIGO từ 0-2 điểm.