bluuebunny/crossref_metadata_2025 huggingface dataset:
Analyse sémiotrice d’un praxème : le dribble et ses interprétations
Authors: Bordes Pascal
Published: September 2022

Considéré comme l’action individuelle par excellence, le dribble renvoie le plus souvent à l’exercice d’une maîtrise technique que seuls quelques protagonistes d’exceptions sont à même d’exécuter. Cette image purement descriptive, centrée sur le seul pratiquant, n’entretient qu’un lointain rapport avec la réalité de ce qui constitue la raison d’être profonde de cette action motrice. Le dribble, entendue comme un acte qui consiste à conduire un objet, – une balle, un palet –, en alternant des temps de contact et de non contact, est avant tout à envisager dans sa dimension collective. Là est le point aveugle des analyses menées à son propos.

Dans cette étude, on considérera le dribble comme un type de conduite motrice porteur d’intentions auxquelles sont attachées des significations de nature essentiellement sociale. Fondamentalement le dribble est relation, c’est-à-dire interaction. Il doit être envisagé sous l’angle de la sémiotricité, autrement dit des significations que les pratiquants lui accordent. Sa fonction est essentiellement d’annoncer les actions futures. À ce titre, il renvoie à une classe de comportements tactiques dont les significations relèvent d’une interprétation en situation sous la dépendance directe des règles du jeu sportif considéré. Loin d’être univoque, le dribble doit être envisagé comme un « signe » qui doit être décodé par les pratiquants en fonction de la grammaire du jeu considéré selon un double axe ; syntagmatique et sémantique. Ce travail à pour objectif de repérer les différentes significations possibles du « signe-dribble », considéré comme un praxème.
Korsakoff syndrome and altered pain perception: a search of underlying neural mechanisms
Authors: Wijnia Jan W. , Oudman Erik , Batjes Deirdre M. , Brouwer Brigitte A. , Oey Misha , Postma Albert
Published: September 2022

Objectives

Patients with Korsakoff syndrome (KS) may have a diminished pain perception. Information on KS and pain is scarce and limited to case descriptions. The present study is the first to investigate the underlying neural mechanisms of altered pain perception in patients with KS more systematically.

Methods

We conducted a literature search on neural correlates of pain perception in other neurocognitive disorders in which extensive research was done.

Results

The brain areas that are affected in KS showed considerable overlap with the neural correlates of pain perception in other neurocognitive disorders. We discussed which different aspects of disturbed pain perception could play a role within KS, based on distinct neural damage and brain areas involved in pain perception.

Conclusions

Combining current knowledge, we hypothesize that diminished pain perception in KS may be related to lesioned neural connections between cerebral cortical networks and relays of mainly the thalamus, the periaqueductal gray, and possibly lower brain stem regions projecting to the cerebellum. Based on these neural correlates of altered pain perception, we assume that increased pain thresholds, inhibition of pain signals, and disturbed input to cerebral and cerebellar cortical areas involved in pain processing, all are candidate mechanisms in cases of diminished pain perception in KS. We recommend that clinicians need to be alert for somatic morbidity in patients with KS. Due to altered neural processing of nociceptive input the clinical symptoms of somatic morbidity may present differently (i.e. limited pain responses) and therefore are at risk of being missed.
Concentrations of B cell-activating factor, aquaporin-4 antibody and brain-derived neurotrophic factor in neuromyelitis optica spectrum disorder
Authors: Li Suping , Fu Jing , Xu Fei , Yu Liang , Yu Qian , Yu Nengwei
Published: September 2022

Objectives

To explore the correlations of B cell-activating factor (BAFF), aquaporin-4 antibody (AQP4-Ab) and brain-derived neurotrophic factor (BDNF) with the severity of neuromyelitis optica spectrum disorder (NMOSD).

Methods

Sixty-eight NMOSD patients were selected as an NMOSD group, and 65 patients with non-inflammatory neurological diseases hospitalized in the same period were selected as a control group. The severity of the disease was assessed using the expanded disability status scale (EDSS). Logistic regression analysis was conducted on the influencing factors for the severity of NMOSD. The correlations of BAFF, AQP4-Ab and BDNF with clinical characteristics were studied by Spearman’s analysis.

Results

The patients with EDSS score ≥7 points, number of involved spinal segments ≥5 and recurrence ≥3 times had a lower level of BAFF in the cerebrospinal fluid than the level of those with 4 points ≤ EDSS score <7 points, EDSS score <4 points, number of spinal segments <5 and recurrence <3 times (p<0.05). BAFF concentration was negatively correlated with disease duration, EDSS score, number of involved spinal segments and recurrence status (p<0.05). AQP4-Ab concentration was positively correlated with disease duration, EDSS score, number of involved spinal segments and recurrence status (p<0.05).

Conclusions

The concentrations of BAFF and AQP4-Ab in the cerebrospinal fluid can well predict the progression of NMOSD, correlated with the severity.
Autosegmental-metrical phonology – Unpacking the boxes
Authors: Grice Martine
Published: September 2022

Autosegmental-metrical phonology has shown itself to be a highly successful framework for the description, analysis and comparison of the prosody of many of the world’s languages. What has contributed to the success of this framework is the fact that there is widespread use of prepackaged units within the model – referred to as “complex primitives”. The intonation systems of languages are described as havingedge tonesand, in some cases, also (post-lexical)pitch accents. These are defined in terms of both their association properties and their cueing function within the prosodic system. Edge tones associate with an edge (or a tone bearing unit at the edge) and are a cue to the juncture between prosodic constituents. Pitch accents associate with a head (usually a stressed syllable) and are a cue to prominence. I shall argue that we need to unpack these definitions, providing evidence from Tashlhiyt Berber, Maltese and Italian, languages in which the association properties and cueing functions of intonational tones do not automatically line up in this way.
Autophagy‐linked plasma and lysosomal membrane protein PLAC8 is a key host factor for SARS‐CoV‐2 entry into human cells
Authors: Ugalde Alejandro P , Bretones Gabriel , Rodríguez David , Quesada Víctor , Llorente Francisco , Fernández‐Delgado Raúl , Jiménez‐Clavero Miguel Ángel , Vázquez Jesús , Calvo Enrique , Tamargo‐Gómez Isaac , Mariño Guillermo , Roiz‐Valle David , Maeso Daniel , Araujo‐Voces Miguel , Español Yaiza , Barceló Carles , Freije José MP , López‐Soto Alejandro , López‐Otín Carlos
Published: September 2022

Better understanding on interactions between SARS‐CoV‐2 and host cells should help to identify host factors that may be targetable to combat infection and COVID‐19 pathology. To this end, we have conducted a genome‐wide CRISPR/Cas9‐based loss‐of‐function screen in human lung cancer cells infected with SARS‐CoV‐2‐pseudotyped lentiviruses. Our results recapitulate many findings from previous screens that used full SARS‐CoV‐2 viruses, but also unveil two novel critical host factors: the lysosomal efflux transporter SPNS1 and the plasma and lysosomal membrane protein PLAC8. Functional experiments with full SARS‐CoV‐2 viruses confirm that loss‐of‐function of these genes impairs viral entry. We find that PLAC8 is a key limiting host factor, whose overexpression boosts viral infection in eight different human lung cancer cell lines. Using single‐cell RNA‐Seq data analyses, we demonstrate that PLAC8 is highly expressed in ciliated and secretory cells of the respiratory tract, as well as in gut enterocytes, cell types that are highly susceptible to SARS‐CoV‐2 infection. Proteomics and cell biology studies suggest that PLAC8 and SPNS1 regulate the autophagolysosomal compartment and affect the intracellular fate of endocytosed virions.
Modified Messengers: flatworm stem cells and regeneration are guarded by RNA methylation
Authors: Benham‐Pyle Blair W
Published: September 2022

The contribution of RNA modifications to whole‐body regeneration remains unclear. In this issue, Dagan et al (2022) show that m6a mRNA pathway components are critically required for stem cell differentiation, survival, and tissue renewal in the planarian Schmidtea mediterranea.
Integrating Nosampesuvu Values in History Learning as a Conflict Resolution in Central Sulawesi
Authors: Misnah Misnah , Supriatna Nana , Malla Hamlan Andi Baso
Published: September 2022

Abstract: This study aims to describe values of local wisdom Nosampesuvu Ethnic Kaili and integrate these values into history learning at SMAN 2 as a conflict resolution in Sigi, Central Sulawesi. Methodologically, this study is qualitative and uses an ethnographic approach. The results of the ethnographic study of the local wisdom values of Nosampesuvu are integrated into learning history using classroom action research (CAR) through the Kemmis and Taggart models. The results showed the findings of ethnographic data of local wisdom values of the Kailiethnic Nosampesuvu group in the integration of the culture of Tolerance ( Mosipahami Patuju) into religious values and social values / cooperation. The uniqueness of the local wisdom of the Kailiethnic Nosampesuvu group was developed in the process of learning local history manifested in cultural values, harmony, polite, polite, friendly, responsible, honest values, and tolerance. The results of the integration found that first, there was an increase in teacher activity in the implementation of learning. Second, there is an increase in student learning outcomes. Thirdly, studentsâ€™ attitudes toward values Nosampesuvu after implementing local wisdom learning significantly better than before the learning implementation. Thus the implementation of the local wisdom values of Nosampesuvu in local history subjects was successful.Â Abstrak: Penelitian ini bertujuan untuk mendeskripsikan nilai-nilai kearifan lokal Suku Nosampesuvu Suku Kaili dan mengintegrasikan nilai-nilai tersebut ke dalam pembelajaran sejarah di SMAN 2 sebagai penyelesaian konflik di Sigi, Sulawesi Tengah. Secara metodologis, penelitian ini bersifat kualitatif dan menggunakan pendekatan etnografi. Hasil kajian etnografi nilai-nilai kearifan lokal Nosampesuvu diintegrasikan ke dalam pembelajaran sejarah dengan menggunakan penelitian tindakan kelas (PTK) melalui model Kemmis dan Taggart. Hasil penelitian menunjukkan temuan data etnografi nilai-nilai kearifan lokal kelompok Kailiethnic Nosampesuvu dalam integrasi budaya Toleransi (Mosipahami Patuju) ke dalam nilai-nilai agama dan nilai-nilai sosial / kerjasama. Keunikan kearifan lokal kelompok Kailiethnic Nosampesuvu dikembangkan dalam proses pembelajaran sejarah lokal yang diwujudkan dalam nilai-nilai budaya, kerukunan, santun, santun, ramah, bertanggung jawab, nilai-nilai kejujuran, dan toleransi. Hasil integrasi menemukan bahwa pertama, terjadi peningkatan aktivitas guru dalam pelaksanaan pembelajaran. Kedua, ada peningkatan hasil belajar siswa. Ketiga, sikap siswa terhadap nilai-nilai Nosampesuvu setelah melaksanakan pembelajaran kearifan lokal secara signifikan lebih baik dibandingkan sebelum pelaksanaan pembelajaran. Dengan demikian penerapan nilai-nilai kearifan lokal Nosampesuvu dalam mata pelajaran sejarah lokal berhasil dilaksanakan.Â
Demak as the Maritime Kingdom on the North Coast of Java
Authors: Arrauf Nasution Ismail Fahmi , Himawan Anang Haris
Published: September 2022

Abstract: This article focuses on the maritime activities of the Demak Kingdom. This research uses historical methods with a qualitative approach to critically analyze literature and related empirical data. This article wants to explore Demakâ€™s economic strategies in utilizing its opportunities so that Demak grows into the largest maritime kingdom in the Archipelago of its time. An important finding from Demakâ€™s maritime study is that this kingdom can take advantage of the available opportunities, optimize its potential, and make a policy, which is the key to Demakâ€™s success. (1) Conducive social conditions with open public attitudes; (2) strategic positions between two significant maritime levels, namely Malacca and Maluku; (3) building good relations with allied countries and being wise in dealing with rivals; (4) utilizing Majapahit heritage assets, optimizing the results of Javaâ€™s natural wealth; and (5) multi attitude towards the status of relations with various countries depending on the type of relations.Â Abstrak: Artikel ini berfokus pada aktivitas maritim Kerajaan Demak. Penelitian ini menggunakan metode sejarah dengan pendekatan kualitatif untuk menganalisis secara kritis literatur dan data empiris terkait. Artikel ini ingin mendalami strategi ekonomi Demak dalam memanfaatkan peluangnya sehingga Demak tumbuh menjadi kerajaan maritim terbesar di Nusantara pada masanya. Temuan penting dari studi maritim Demak adalah kerajaan ini dapat memanfaatkan peluang yang ada, mengoptimalkan potensinya, dan membuat kebijakan yang menjadi kunci keberhasilan Demak. Secara rinci faktor pendorong kesuksesan Demak adalah (1) Kondisi sosial yang kondusif dengan sikap publik yang terbuka; (2) posisi strategis antara dua tingkat maritim penting, yaitu Malaka dan Maluku; (3) membangun hubungan baik dengan negara-negara sekutu dan bersikap bijak dalam menghadapi rival; (4) Memanfaatkan aset peninggalan Majapahit, mengoptimalkan hasil kekayaan alam Jawa; dan (5) sikap multi terhadap status hubungan dengan berbagai negara tergantung pada jenis hubungan.Â
Europeesche Lagere School and the Birth of Bumiputera Intellectual Elite in Bojonegoro, East Java
Authors: Pratiwi Evita , Husain Sarkawi B
Published: September 2022

This article discusses the implementation of schools for European children to the birth of the Bumiputera elite in Bojonegoro in 1892-1942. The ethical politics that were introduced in the early 20th century had a significant influence on the development of colonial education in Bojonegoro. In addition, the awareness of the colonial education presence for European children during the Dutch colonial rule also influenced the presence of European elementary schools in this city. It was purposed to facilitate the majority of European children whose parents were colonial employees, plantation owners, or the gas industry. This article is the result of research using historical methods, namely, source collection, source verification or criticism, analysis, and writing or historiography. The first European Elementary School (Europeesche Lagere School) opened in Bojonegoro in 1892 which was located in the Bojonegoro District. This school applied the same rules as schools in the Netherlands. Initially the school only accepted students of European nationality, but in later development it also accepted Bumiputera children with strict conditions. The school, which was intended to produce European educated people, then also gave birth to a new intellectual elite called as Bumiputera, who later became the driving force for movement and press organizations.Artikel ini membahas tentang penyelenggaraan sekolah untuk anak-anak Eropa hingga lahirnya elit bumiputera yang ada di Bojonegoro pada tahun 1892-1942. Politik etis yang digulirkan pada awal abad ke-20 memberi pengaruh yang signifikan terhadap berkembangnya pendidikan kolonial di Bojonegoro. Selain itu, kesadaran untuk hadirnya pendidikan kolonial untuk anak-anak Eropa pada masa pemerintahan kolonial Belanda turut berpengaruh pada hadirnya sekolah dasar Eropa di kota ini. Hal ini untuk memfasilitasi banyakanya anak-anak Eropa yang orang tuanya menjadi pegawai kolonial, pemilik perkebunan, atau industri gas. Artikel ini merupakan hasil penelitian dengan menggunakan metode sejarah yaitu, pengumpulan sumber, verifikasi atau kritik sumber, analisis,  dan penulisan atau historiografi. Sekolah Dasar Eropa (Europeesche Lagere School)  pertama yang dibuka di Bojonegoro yakni pada tahun 1892 yang berlokasi di Distrik Bojonegoro. Sekolah ini menerapkan peraturan yang sama dengan sekolah yang ada di Belanda. Awalnya sekolah hanya menerima murid-murid berkebangsaan Eropa, namun dalam perkembangan kemudian juga menerima anak-anak bumiputera dengan persyaratan yang ketat. Sekolah yang diperuntukkan untuk mencetak kaum terdidik Eropa, kemudian   juga melahirkan elit intelektual baru bumiputera yang kemudian menjadi penggerak organisasi pergerakan dan pers.
Narratives of Nationalism in Indonesia and Malaysia’s History Textbooks
Authors: Mulyana Agus
Published: September 2022

History textbooks are historical writings that have a function in developing educational values, including nationalism. Indonesia has a historical background colonized by the West, so that history textbooks will create nationalism’s value. This study aims to see how nationalism is described in the history textbooks of the two countries through historical events. The method used in this research is content analysis, namely analyzing the textbook’s narrative based on the indicators of the theory of nationalism. The findings of this study are indicators of the idea of nationalism, which includes myths of past glory, ethnicity and diversity, and colonialism in the description of historical events. This study concludes that the indicators of nationalism in history textbooks in Indonesia and Malaysia narrate in an indoctrinating language by placing nationalism as an ideology.Buku teks sejarah adalah tulisan sejarah yang memiliki fungsi dalam mengembangkan nilai-nilai pendidikan, termasuk nasionalisme. Indonesia memiliki latar belakang sejarah yang dijajah oleh Barat, sehingga buku teks sejarah akan melahirkan nilai nasionalisme. Penelitian ini bertujuan untuk melihat bagaimana nasionalisme digambarkan dalam buku teks sejarah kedua negara melalui peristiwa sejarah. Metode yang digunakan dalam penelitian ini adalah analisis isi, yaitu menganalisis narasi buku teks berdasarkan indikator teori nasionalisme. Temuan penelitian ini adalah indikator gagasan nasionalisme, yang meliputi mitos kejayaan masa lalu, etnisitas dan keragaman, dan kolonialisme dalam deskripsi peristiwa sejarah. Penelitian ini menyimpulkan bahwa indikator nasionalisme dalam buku teks sejarah di Indonesia dan Malaysia dinarasikan dalam bahasa yang indoktrinasi dengan menempatkan nasionalisme sebagai ideologi.
Volar locking plate vs cast immobilization for distal radius fractures: a systematic review and meta-analysis
Authors: Oldrini Lorenzo Massimo , Feltri Pietro , Albanese Jacopo , Lucchina Stefano , Filardo Giuseppe , Candrian Christian
Published: September 2022

Introduction

The aim of this systematic review and meta-analysis was to evaluate whether volar locking plate (VLP) fixation leads to better clinical and radiological outcomes than those of closed reduction and cast immobilization for the treatment of distal radius fractures (DRFs).

Materials and methods

A comprehensive literature search was performed in PubMed, Web of Science, and Cochrane databases up to January 2022. Inclusion criteria included randomized controlled trial (RCT) studies comparing VLP fixation with cast immobilization for DRFs. Investigated parameters were Patient-Rated Wrist Evaluation questionnaire, Disabilities of the Harm, Shoulder, and Hand score (DASH), range of motion (ROM), grip strength, quality of life (QoL), radiological outcome, and complication and reoperation rate, both at short- and mid-/long-term follow-up. Assessment of risk of bias and quality of evidence was performed with Downs and Black’s ‘Checklist for Measuring Quality’.

Results

A total of 12 RCTs (1368 patients) were included. No difference was found for ROM, grip strength, QoL, and reoperation, while the DASH at 3 months was statistically better in the VLP group (P <  0.05). No clinical differences were confirmed at longer follow-up. From a radiological perspective, only radial inclination (4°) and ulnar variance (mean difference 1.1 mm) at >3 months reached statistical significance in favor of the VLP group (both P < 0.05). Fewer complications were found in the VLP group (P < 0.05), but they did not result in different reintervention rates.

Conclusions

This meta-analysis showed that the surgical approach leads to a better clinical outcome in the first months, better fracture alignment, and lower complication rate. However, no differences in the clinical outcomes have been confirmed after 3 months. Overall, these findings suggest operative treatment for people with higher functional demand requiring a faster recovery, while they support the benefit of a more conservative approach in less demanding patients.
A systematic approach to CT evaluation of non-arthritic hip pain
Authors: Curley Andrew J , Ruh Ethan R , Shah Amisha , Disantis Ashley E , Krivoniak April , Mauro Craig S , McClincy Michael P
Published: September 2022

Bone morphology has been increasingly recognized as a significant variable in the evaluation of non-arthritic hip pain in young adults.

Increased availability and use of multidetector CT in this patient population has contributed to better characterization of the osseous structures compared to traditional radiographs.

Femoral and acetabular version, sites of impingement, acetabular coverage, femoral head–neck morphology, and other structural abnormalities are increasingly identified with the use of CT scan.

In this review, a standard CT imaging technique and protocol is discussed, along with a systematic approach for evaluating pelvic CT imaging in patients with non-arthritic hip pain.
The effects of syringaldehyde and vanillin on butyric acid production by fermentation using Clostridium tyrobutyricum
Authors: Liu Ying , Geng Yingxi , Zhou Quan , Yuan Wenqiao
Published: September 2022

Butyric acid is a valuable chemical that has various applications in the chemical, pharmaceutical, food, and biofuel industries. Its bio-fermentation from lignocellulosic materials may be affected by some unwanted substrates that are generated during biomass pretreatment processes. In the present study, the potential inhibitory effects of two phenolic aldehydes (syringaldehyde and vanillin) on butyric acid fermentation by Clostridium tyrobutyricum were evaluated. The toxicity of syringaldehyde and vanillin on cell growth, xylose consumption, and butyric acid production was dosage-dependent. The butyric acid productivity decreased significantly with increasing concentrations of syringaldehyde and vanillin. C. tyrobutyricum demonstrated a broad tolerance to both syringaldehyde and vanillin and only moderate reductions in the maximum cell density were observed with up to 2.4 g L-1 of syringaldehyde or vanillin in the medium. Both syringaldehyde and vanillin were assimilated by C. tyrobutyricum, and the metabolite products from vanillin caused considerable inhibition of the fermentation.
Global Perspectives on the Health and Social Impacts of Child Trafficking
Authors: Wallace Carmelle , Greenbaum Jordan , Albright Karen
Published: September 2022

BACKGROUND AND OBJECTIVES

Survivors of child sex trafficking (CST) experience many health and social sequelae as a result of stigma, discrimination, and barriers to health care. Our objective was to obtain a cross-cultural understanding of these barriers and to explore the relationship between stigmatization and health outcomes through application of the Health Stigma and Discrimination Framework (HSDF).

METHODS

In-depth, semistructured interviews were conducted with 45 recognized CST expert service providers. Interview data were analyzed using established content analysis procedures and applied to the HSDF.

RESULTS

Barriers to medical and mental health services span each socioecological level of the HSDF, indicating the various contexts in which stigmatization leads to adverse health and social outcomes. Stigmatization of CST survivors is a complex process whereby various factors drive and facilitate the marking of CST survivors as stigmatized. Intersecting stigmas multiply the burden, and manifest in stigma experiences of self-stigmatization, shame, family and community discrimination, and stigma practices of provider discrimination. These lead to reduced access to care, lack of funding, resources, and trained providers, and ultimately result in health and social disparities such as social isolation, difficulty reintegrating, and a myriad of physical health and mental health problems.

CONCLUSIONS

The HSDF is a highly applicable framework within which to evaluate stigmatization of CST survivors. This study suggests the utility of stigma-based public health interventions for CST and provides a global understanding of the influence and dynamics of stigmatization unique to CST survivors.
Remodelling a Medieval Net Vault Construction •
Authors: Jobbik Eszter , Krähling János
Published: September 2022

In the present study, we analysed the exact, laser-scanned geometry of the apse vault of the catholic church of Andocs. The written sources about this vault are very limited, however, the point cloud-based research could provide new details about the history of the building, along with the formerly used building techniques. For the analysis, we worked based on our three-step analysis process, established for net vaults. During the studying of the rib system, we reconstructed the probable original construction and building method, as well as the temporary supporting structures of the early 16th-century vault. The analysis of the individual ribs led us to conclusions about this vault, in the mirror of the widespread ideas of the topic’s technical literature, such as the “Prinzipalbogen” theory (all the ribs of a given net vault have the same curvature), or the principle of the longest route (the cumulated length of the ribs’ plan, which led from the impost to the crown with the longest possible route equals to the radius of the ribs’ curvature). Regarding the curvilinear rib elements, we presumed a likely fabrication method, based on contemporary research results. Mapping the webbing and the ribs, we concluded their building order, as well as the plausible masonry technique of the webs.
İnanç Turizminde Merkezler ve Bölge İnsanının Bu Merkezlerle Etkileşimi: Kastamonu Örneği
Authors: ÇILGINOĞLU Hakkı , HELVECİ Ümit
Published: September 2022

Ulaşımın kolaylaşması, sanayileşme, boş zamanın artması, eğitim düzeyinin yükselmesi ve kişi başına düşen gelir düzeyinin artması gibi nedenlerle birey; turistik gezilere yönelebilmektedir. Bu yönelimi artırmak ve bireyi monoton yaşamından uzaklaştırabilmek için geleneksel kitle turizmi yanında ortaya çıkan alternatif turizm türleriyle ilgili farkındalık çalışmalarına önem verilmesi gerekmektedir. Bu alternatif turizm türleri arasında yer alan, yıl boyunca ve daha düşük maliyetle yerine getirilebilen inanç turizminin önemini artırmaktadır. Araştırmanın amacı; kültür ve inanç turizmi unsurlarından T.C. Kastamonu Belediyesi resmî Web sayfasında yayımlanan ve Merkez ilçede bulunan cami ve külliyeler hakkında farkındalık oluşturmak, Merkez ilçede yaşayanlar tarafından bu unsurların ziyaret oranlarını ölçmektir. Amaca ulaşmak için izinlerin alınması sonrasında Kastamonu ili Merkez ilçesinde en az üç yıl yaşamış 20 yaş üstü 518 katılımcıdan oluşan örneklem grubuna anket uygulaması yapılmıştır. Veriler Google Formlar aracılığıyla gönüllülük ölçütü temel alınarak kolayda örnekleme yöntemiyle toplanmıştır. Araştırmada elde edilen verilerin analizi SPSS İstatistik Analiz Programı kullanılarak yapılmış; verilerin analizi sırasında, betimleyici istatistiklerin yanı sıra Ki-Kare Testi uygulanmıştır. Sonuç olarak araştırmaya katılan katılımcıların inanç turizmi merkezleri hakkında yeterince farkındalığa sahip olmadıkları görülmüştür. Katılımcıların cinsiyet, medeni durum, eğitim, meslek ve aylık gelir durumlarına göre inanç turizmi merkezlerini ziyaret etme durumları arasında anlamlı farklılık vardır. Katılımcılara göre inanç turizmi merkezlerinin turizm bakımından ilgi odağı hâline getirilebilmesi için basın ve yayın organları ile sosyal medyanın etkinliğinden yararlanılması, çeşitli sosyal ve kültürel etkinliklerin düzenlenmesi, inanç turizmiyle ilgili girişimcilere imkânlar sağlanması, konu hakkında eğitimler verilmesi gerekmektedir.
From insect-plant interactions to ecological networks
Authors: Lewinsohn Thomas Michael , Almeida Neto Mário , Almeida Adriana , Prado Paulo Inácio , Jorge Leonardo Ré
Published: September 2022

Abstract Since its inception, biodiversity has largely been understood as species diversity and assessed as such. Interactions among species or functional groups are gradually becoming part of an expanded concept of biodiversity. As a case study of the development of a research program in biodiversity, we summarize our multi-decade studies on interactions of Asteraceae and flowerhead-feeding insects in Brazil. Initially, host species were treated as independent replicates in order to assess the local and turnover components of their herbivore diversity. Research then expanded into sampling entire interactive communities of host plants and their associated herbivores in different localities and regions, enabling new research lines to be pursued. Interaction diversity could be assessed and factored into spatial and among-host components, suggesting a new field of interaction geography. Second, host specialization, a key component of interaction diversity, was reframed considering simultaneously relatedness and local availability of plant hosts. Third, with the influence of complex network theory, community-wide species interactions were probed for topological patterns. Having identified the modular structure of these plant-herbivore systems, later we demonstrated that they fit a compound hierarchical topology, in which interactions are nested within large-scale modules. In a brief survey of research funded by Fapesp, especially within the Biota-Fapesp program, we highlight several lines of internationally recognized research on interaction diversity, notably on plant-frugivore and plant-pollinator interactions, together with new theoretical models. The interplay of field studies with new theoretical and analytical approaches has established interaction diversity as an essential component for monitoring, conserving and restoring biodiversity in its broader sense.
EQUIVARIANT GEOMETRIC LEARNING FOR DIGITAL ROCK PHYSICS: ESTIMATING FORMATION FACTOR AND EFFECTIVE PERMEABILITY TENSORS FROM MORSE GRAPH
Authors: Cai Chen , Vlassis Nikolaos , Magee Lucas , Ma Ran , Xiong Zeyu , Bahmani Bahador , Wong Teng-Fong , Wang Yusu , Sun WaiChing
Published: September 2022

We present a SE(3)-equivariant graph neural network (GNN) approach that directly predicts the formation factor and effective permeability from micro-CT images. Fast Fourier Transform (FFT) solvers are established to compute both the formation factor and effective permeability, while the topology and geometry of the pore space are represented by a persistence-based Morse graph. Together, they constitute the database for training, validating, and testing the neural networks. While the graph and Euclidean convolutional approaches both employ neural networks to generate low-dimensional latent space to represent the features of the microstructures for forward predictions, the SE(3) equivariant neural network is found to generate more accurate predictions, especially when the training data are limited. Numerical experiments have also shown that the new SE(3) approach leads to predictions that fulfill the material frame indifference whereas the predictions from classical convolutional neural networks (CNNs) may suffer from spurious dependence on the coordinate system of the training data. Comparisons among predictions inferred from training the CNN and those from graph convolutional neural networks with and without the equivariant constraint indicate that the equivariant graph neural network seems to perform better than the CNN and GNN without enforcing equivariant constraints.
Shear strength anisotropy of rooted soils
Authors: Karimzadeh Ali Akbar , Leung Anthony Kwan , Gao Zhiwei
Published: September 2022

The shear strength of rooted soils depends on the principal stress direction owing to the anisotropy in the soil structure and root system. Existing failure criteria cannot describe the strength anisotropy of rooted soils under general loading conditions because they are mainly based on the test results of direct shear. This study presents a new generalised three-dimensional anisotropic failure criterion for rooted soils. The model employs the projection of two independent microstructure fabric tensors (soil fabric and root network) on the stress tensor. Twenty-four drained triaxial compression and extension tests were carried out to measure the strength anisotropy of silty sand vegetated with vetiver grass (Chrysopogon zizanioides L.) at different overconsolidation ratios and calibrate the material parameters for the proposed criterion. Anisotropies of both cohesion and friction angle exist in rooted soil. Roots contribute mainly to the increase in cohesion (hence root cohesion) from most of the direct shear test data. Roots with predominant orientation aligning in the tensile strain direction contribute the most to soil strength. In the case of vetiver grass, which has a taproot system, their roots show the strongest reinforcement effect in the conventional triaxial extension path, in which the maximum portion of the roots is subjected to tension.
Classification of electrical status epilepticus in sleep based on EEG patterns and spatiotemporal mapping of spikes
Authors: Balaram Neetha , Jose James , Gafoor Abdul V. , Balachandran Smita
Published: September 2022

Objective. We firstly aimed to describe and classify EEG patterns in electrical status epilepticus in sleep (ESES), and secondly subclassify EEG patterns based on analysis of spikes using spatio‐temporal mapping and electrical source analysis.

Methods. Overnight EEGs (minimum: eight hours) of 30 children, aged 2‐12 years, with ESES (spike‐wave index: at least 50%) were selected. Average reference montage was used for dipole analysis and mapping. The location and orientation of the dipoles were determined by mapping positive and negative poles and applying the rules of mapping. The onset and propagation of the spikes and the latency between the two hemispheres (for bisynchronous spikes) were determined (based on source analysis using BESA research 7.1).

Results. (1) ESES was classified as “generalised” (80%) and focal (20%) patterns; (2) the bisynchronous subtype in the “generalised” pattern was due to apparently synchronous bilateral activation of spikes (with lead‐in of 20‐60 ms from one hemisphere) with a tangential/oblique dipole (source analysis localised these spikes to around the peri‐rolandic cortex); (3) the classic description of ESES spikes as “diffuse” spikes with bifrontal maxima is a misinterpretation using the 10‐20 EEG system. Using voltage mapping and source analysis, cortical activation in the rolandic cortex was identified which imparts diffuse frontal negativity and parieto‐occipital positivity; (4) ESES spikes showed intraspike and interspike dipole instability and the orientation of dipoles changed due to local spike propagation around the source and into the depth of the sulcus (which we refer to herein as “dancing dipoles”); and (5) focal ESES were classified as parietal, occipital and temporo‐occipital patterns; a frontal ESES pattern was not seen.

Significance. Based on detailed mapping and source analysis of ESES, we have successfully reinterpreted various misconceptions in the literature. We have simplified the interpretation of complicated EEG patterns by extracting the primary and propagated sources which aid the classification of ESES. As the dipole is always stable in self‐limited childhood epilepsy with centrotemporal spikes, we believe that the phenomenon of an intrinsically unstable dipole is a reliable qualitative EEG marker of ESES.
Esettanulmányok az első világháborúban szolgált New York-i magyar katonák köréből
Authors: Ambrus László
Published: September 2022

A tanulmányban a szerző olyan New York államban élt magyar bevándorlók életútját ismerteti, akik minden kétséget kizáróan szolgáltak az amerikai hadsereg kötelékében az első világháborúban. A kutatás célja, hogy egy biográfiai adattárat építsen fel ezekről az amerikai magyar newyorkerekről. Vida István Kornél korábbi számításai szerint az amerikai hadseregnek kb. 3.000 magyar katonája lehetett a háborúban. A munka távlati célja ennek igazolása, illetve pontosítása. A kutatás alapján az a hipotézis állítható fel, hogy ha Vidának igaza van a 3.000 főnyi magyar katonával kapcsolatban, akkor ennek a számnak több mint egy negyede New York állam „amerikás” magyarjai közül került ki. A magyar és amerikai levéltárakban, illetve online adattárakban folytatott kutatás további célja lesz a biográfiai adatbázis bővítése és finomítása, illetve a vizsgálódás kiterjesztése a többi amerikai állam területére. A dolgozat röviden ismerteti a kutatás forrásait, majd bemutat négy izgalmas példát a jól feltárható egyéni életpályák közül.
Madrid határán (Az egri Láng Sándor útja a spanyol polgárháborúba)
Authors: Bartók Béla
Published: September 2022

Láng Sándor 1914-ben született Egerben Webermann Sándor néven jómódú polgárcsaládban, és az ottani állami főreáliskolában érettségizett. Csehszlovákiában kezdte meg egyetemi tanulmányait, ahol megismerkedett a kommunista ideológiával. 1936-ban azonban ismerőseivel együtt Spanyolországba utazott, ahol belépett a lázadó nemzeti fegyveres erők ellen a köztársaságot védelmező egyik nemzetközi brigádba. Előbb a Dimitrovról, majd a Rákosi Mátyásról elnevezett zászlóaljban szolgált más kelet-európai önkéntesekkel együtt, részt vett néhány ütközetben, végül 1937-ben 23 évesen harcban esett el. Sorsát Egerben csak 1956 után ismerték meg, de internacionalizmusa és elszántsága miatt kisebb kultusz alakult ki körülötte. A tanulmány Láng Sándor ifjúkorának és más hasonló életpályáknak az elemzésével azt próbálja bemutatni, milyen okai lehettek az „osztályidegen” egri fiatalember kalandos életútjának és tragikus halálának.
„Kaktuszerdők” és „fekete nők” : Kiskunhalasi katonák a Mexikói Önkéntes Hadtestben
Authors: Végső István
Published: September 2022

A tanulmány bemutatja, hogy mit tudunk a „verbunkozva” összeszedett kiskunhalasi katonákról, akik a mexikói hadszíntéren 1864 és 1867 között huszárként harcoltak. A gyarmatosítások korának anakronisztikus vállalkozása volt, hogy egy bécsi születésű Habsburg kerüljön egy latin-amerikai állam császári trónjára. I. Miksa mexikói császár (1863–1867) kalandorvállalkozása csúfos és tragikus véget ért. A különleges expedíciónak nem kevés magyar, sőt kiskunhalasi tagja is volt. A kiskunhalasi levéltári, könyvészeti és hírlapi források szerint 11 kiskunhalasi katona vonult be a Mexikói Önkéntes Hadtestbe (Mexikanische Österreichische Freiwilligenkorps), és járta meg a közép-amerikai hadszínteret. Közülük hárman: Bakodi Antal, Révész István és Zana Mihály huszárok személyes élményeiket is elmesélték. Persze a hatalmas, távoli országban történteket kissé kiszínezve adták elő. A téma kutatója, Tardy Lajos történész által összegyűjtött, önkéntes katona-nyilvántartás alapján többeket be tudunk azonosítani a kiskunhalasiak közül. 1864-es toborzásuk néptánc- és népzenetörténeti jelentőségű, hiszen az egyik utolsó kiskunhalasi (kun)verbunkként tartja számon a szakirodalom.
Kinde ve Mezhic Kralı Mâlik b. Muâviye’nin Himyerî Kralı Şemmer Yuhar`iş’i Me’rib’teki Ziyareti
Authors: MARAQTEN Mohammed
Published: September 2022

Sebe diline ait ve mB 2006 İ-54 (şek. 2) olarak adlandırılan kitabe, siglum/müstensih (yani yazar) kısaltması içermekte ve Yemen/Me’rib yakınlarındaki Avâm Tapınağı/Maḥrem Belkîs’ta Sebe tanrısı el-Makah’a adanmış bronz bir heykelciğin kaydını taşımaktadır (Maraqten 2015: 109–135).

Öğenin Açıklaması: Heykelciğin alt kısmı şu an kayıptır ve yazıt tek bir yüze kazınmıştır. Yazıt, biraz aşağı eğilmiş ve çift, hafifçe kazınmış yatay çift çizgiler şeklinde oyulmuştur. Taşın yüzeyi parlatılmış; heykelciğin yapışık olduğu üst yüzey kırılmış ve ilk satır neredeyse tamamen kaybolmuş vaziyettedir. Sol alt köşe kırılmış ve taşın bazı kenar bölümleri hafifçe zarar görmüştür. Metin, ilk satırdaki birkaç kayıp harf dışında eksiksiz vaziyettedir. Yazıtın üst kısmı kısmen kaybolmuş olsa da transkripsiyonda gösterildiği üzere 11. satıra atıfta bulunarak yeniden oluşturulması mümkündür.

Bu 14 satırlık yazıt; 9. AFSM’nin (American Foundation for the Study of Man/Amerikan İnsan Araştırmaları Vakfı) 2006 yılı sezonunda düzenlediği kazılarda, Avâm Tapınağının ek binasında keşfedildi ve zeminin döşenmesinde yeniden kullanıldı. Yazılı bloğun ölçüleri aşağıdaki gibidir: 35×22cm; harf yüksekliği: 1,5×1,7cm. Kavisli el-Makah sembolü satır bir ve ikinin başlangıcında göze çarpmaktadır; ancak üst kısmı kırılmıştır. Yazıtın bugünkü konumu Avâm Tapınağı’dır ve hala yerindedir
PROSTAT KANSERİ MOLEKÜLER PATOGENEZİ
Authors: ERTUNÇ Onur , TUNA Burçin
Published: September 2022

Prostat kanseri dünya genelinde erkeklerde akciğer karsinomundan sonra 2. en sık ölüme yol açan kanserlerdir. Her ne kadar erken tedavi ve koruyucu hekimlik uygulamalarının PSA takibi şeklinde ön plana çıkmasıyla, devamında iğne biyopsilerle hastaların tümör gelişiminin saptanması kolaylaşmış olsa da tümörün özellikle tedavi öncesinde, sırasında ve sonrasındaki davranışlarının belirlenmesi anlamında elimizde risk skorlama şemaları dışında pek bir şansımız yoktu. Günümüzde kişiye özgü tedavi modellerini belirlemede ve hastalığın ileri evre olmadan prognozunu tahmin etmede kullanabileceğimiz moleküler imzası ve moleküler biyolojisi önem arz etmektedir. Tüm bu nedenlerle prostat kanserinin moleküler patogenezi ve biyolojik davranışının medikal profesyoneller tarafından bilinmesi hastalığı ve seyrini anlamada bize yardımcı olacaktır.
Worm Synchronization Protocol (Bleaching) v1
Authors: Al-Asmar Alid
Published: September 2022

A protocol for synchronizing a large number of C. elegans worms. Worm bodies are decomposed using a mixture of bleach and sodium hydroxide, for a short enough time, so that eggs are not damaged. These eggs are then left to hatch in liquid, and the resulting L1's all have approximately the same age. Source of the original protocol: Wormbook Methods: http://wormbook.org/toc_wormmethods.html Synchronization protocol: Porta-de-la-Riva, M., Fontrodona, L., Villanueva, A., Cerón, J. Basic Caenorhabditis elegans Methods: Synchronization and Observation. J. Vis. Exp. (64), e4019, doi:10.3791/4019 (2012).
Creating Gelvatol Solution v1
Authors: Boassa Daniela
Published: September 2022

A gel-like mounting media (with an anti-fade ingredient) for fluorescence slides.
Staphylococcus Aureus Sampling v2
Authors: Roca Cugat Mar
Published: September 2022

This protocol is intended to study the affectation of Staphylococcus Aureus, including the MRSA, VISA and VRSA variants, even if it makes the test more difficult to perform. It outlines the basic protocol for a multi-subject study, while using basic and minimal resources found in almost every biology lab.
CTAB genomic DNA extraction from Arabidopsis leaf material v2
Authors: R Ganguly Diep
Published: September 2022

CTAB-based extraction of genomic DNA fromArabidopsis leaf tissue.
Students Readiness in Online Lectures During the Pandemic: What is the Ideal Lecture Model?
Authors: Dwiharyadi Anda , Afni Zalida , Aulia Rentih
Published: September 2022

Abstract. This study identifies the readiness, perceptions and preferences of students in facing online learning. This study will also propose an effective online learning model design. Data obtained from 362 students through a questionnaire using a likert scale. The results shows that in general the students are ready to carry out the process of online learning. Besides using a live conference media, students prefer the use of teaching videos made by lecturers himself as an alternative method when quota and internet signals are the main problems. The distribution of learning materials should be carried out at least one day before the learning schedule. Meanwhile, the allocation of lecture time is not too much in the attendance process. Furthermore, the evaluation process is also carried out for each material topic. Thus, the focus of the on learning model should consider teaching media, material distribution, time allocation and learning evaluation process. Keywords: readiness, preferences, on line learning; effective
Understanding of Professional Sckeptis: Are The Sequence of Evidence and Critical Thinking Determining Factors? (Experimental Research)
Authors: Apandi R Nelly Nur , Sofia Alfira , Zulhaimi Hanifa
Published: September 2022

Understanding professional skepticism will help the auditor to assess the risks of material misstatement in the financial statements appropriately. One of the efforts lecturers can make to improve this understanding is through an audit learning model that links efforts to collect and evaluate audit evidence into question exercises. This study aims to see audit learning regarding evidence collection (sequence of evidence) and evidence assessment (critical thinking about mitigation risk) can influence students' understanding of skepticism. The research was conducted on 120 students of the UPI accounting study program class of 2017 and 2018. The research method was carried out by experiment. The research design in this study used a 2x2 factorial design. The study results prove that learning about evidence collection (sequence of evidence) and assessment of evidence (critical thinking about mitigation risk) increases understanding of professional skepticism. The study results have implications for the development of audit learning methods that emphasize critical thinking efforts about risk mitigation that can increase students' understanding of professional skepticism.
The Effect of Product Quality on Customer’s Satisfaction and Loyalty of EMN Brand in the Ecommerce Era
Authors: Samir Vivi Fitriyanti , Sampurno Sampurno , Derriawan Derriawan
Published: September 2022

Introduction: business cosmetic has grown rapidly in the e-commerce era. In the e-commerce era, companies have the opportunity to expand their sales system to increase customer satisfaction.The purpose of study: to determine and analyze the effect of e-commerce and EMN product quality on satisfaction and its impact on consumer loyalty.Research Method: descriptive study with quantitative methods. The data was collected by distributing a survey to 155 respondents who had purchased EMN products through e-commerce sites at least once in the last six months. The survey data analysis used the SEM (Structural Equation Modeling) analysis of the SPSS 25 and AMOS 24 programs.Results: the results showed that each variable influenced each other. E-commerce has a positive effect on customer satisfaction, where the p-value = 0.014 (0.05) and the coefficient is 0.347. Product quality has a positive effect on customer satisfaction with p-value = 0.000 (0.05) and a coefficient of 0.546. Satisfaction has a significant effect on loyalty with p-value = 0.000 (0.05) and a coefficient of 0.798. Meanwhile, e-commerce has a negative effect on consumer loyalty with a p-value = 0.23 and a coefficient of -0.408. Product quality has a positive and significant effect on consumer loyalty with p-value = 0.39 and a coefficient of 0.416.Conclusion: Companies have to create attractive e-commerce site designs with complete and accurate attributes and information; companies must maintain the availability and completeness of products in e-commerce; creating a new product with a packaging design that is more attractive and of sufficiently good quality.