bluuebunny/crossref_metadata_2025 huggingface dataset:
RELATIONSHIP OF APELIN-12 LEVEL AND TYPES OF LEFT VENTRICULAR REMODELING IN PATIENTS WITH ARTERIAL HYPERTENSION AND TYPE 2 DIABETES
Authors: Tabachenko O. S.
Published: July 2021

It was examined 105 patients with arterial hypertension (AH). The study group included 75 patients with a combination of arterial hypertension and diabetes mellitus (DM) type 2 (mean age 60,03 ± 1,17). Evaluated changes in structural and functional parameters of left ventricular myocardium depending on the apelin-12 level in patients with arterial hypertension and diabetes mellitus type 2 for the analysis of the effect of apelin-12 concentration on the formation of a certain type of myocardium remodeling. Apelin-12 level above 75 percentile (more 1,725 ng/ml) has an antagonistic effect on left ventricular hypertrophy in patients with arterial hypertension and diabetes mellitus type 2. The duration of diabetes mellitus type 2 more 5 years with apelin-12 concentration in the range from 25 to 75 percentile and less 25th percentile is associated with the development of concentric hypertrophy and eccentric left ventricular hypertrophy in patients with hypertension.
PSYCHO-EMOTIONAL STATUS AND QUALITY OF LIFE ASSESSMENT IN PATIENTS WITH TYPE 1 DIABETES MELLITUS
Authors: Khyzhnjak O. , Tikhonova T. , Barabash N. , Svetlova-Kovalenko E. , Burma T.
Published: July 2021

The data of study to determine the emotional state of 84 patients with type 1 diabetes mellitus and their self-assessment of quality of life was given in the article. According to the study design all patients were divided into 2 groups depending on labile or relatively stable course of disease. The control group consisted of 22 healthy persons. Due to the application of generally accepted questionnaire use the absence of the ability adequate perception of their condition were determined in significant number of patients in both groups. This fact should be seen as a barrier to effective selfmanagement and, consequently, to achieve of satisfactory metabolic parameters. At the same time, the lack of «obsession» on the disease for a certain number of persons with type 1 diabetes mellitus indicates their perception of the disease as lifestyle.
CHRONOBIOLOGICAL ASPECTS OF MELATONIN INFLUENCE ON THE SEVERAL COMPONENTS OF THE METABOLIC SYNDROME IN HYPOPINEALISM
Authors: Bondarenko L. O. , Mishchenko T. V. , Poltorak V. V. , Sotnyk N. M.
Published: July 2021

It was studied the effects of melatonin administration (2,5 mg/kg b. w. intramuscularly for 10 days) on circadian rhythms of the metabolic syndrome main components parameters on young adult rabbits with metabolic syndrome on the background of hypopinealism induced by long (for 5 months) day and night lighting. It was established that chronic treatment with this indolamine induced restoration of circadian rhythms of insulin and glucose levels in serum, decrease of insulin resistance manifestations, reduce abdominal-visceral fat weight, lowering the concentration and recovery leptin circadian rhythms in the serum. It was also revealed, that melatonin administration demonstrate antihypertensive effect, but don’t restore systolic blood pressure circadian rhythm in studied rabbits.
HEPATOPROTECTIVE ACTIVITY OF SPERMATOZOID STIMULATOR — KATIAZYN UNDER CONDITIONS OF EXPERIMENTAL PARACETAMOL-INDUCED LIVER PATHOLOGY
Authors: Kudria M. Ya. , Melnikivs’ka N. V. , Ustenko N. V. , Pavlenko T. O. , Lalymenko O. S. , Palagina I. A. , Degtyaryova A. L. , Ivashchenko A. D.
Published: July 2021

It was investigated hepatoprotective properties of camphor acid derivative — katiazin under experimental model conditions of paracetamol drug-induced hepatitis. It was proved that katiazin in two doses (10 and 50 mg/kg body weight) stimulates the non-enzymatic antioxidant defense unit, increasing the concentration of the reduced glutathione and sulfhydryl groups. The application of katiazin led to an increase in the prothrombin time, which can be interpreted as a sign of the compound anticoagulant effect. It was found out that the administration of katiazin enhances liver detoxification function, normalizes carbohydrate and lipid metabolism in rats.
THE ROLE OF COMPONENTS OF THE EXTRACELLULAR MATRIX IN THE DEVELOPMENT OF ACUTE MYOCARDIAL INFARCTION AND DIABETES MELLITUS TYPE 2 (literature review)
Authors: Koteliukh M. Yu. , Kravchun P. G.
Published: July 2021

The article highlights the influence of matrix metalloproteinases, tissue inhibitors of metalloproteinases and tenascin C onto development and severity of the acute myocardial infarction in the patients with comorbide pathology. It was determined that the levels of matrix metalloproteinases were decreasing, and tissue inhibitors of metalloproteinases were raising in the patients with cardiovascular disease depending on the presence or absence of diabetes mellitus type 2. The attention was compelled to the ability of the extracellular matrix indicators to implement remodeling of the left ventricular myocardium in the patients with acute myocardial infarction and its complications. Here was exposed the changes in the parameters of the patients that have confirmed a promising study of their predicting properties at the development of cardiovascular complications in the patients with the acute myocardial infarction with concomitant diabetes mellitus type 2.
CLINICAL CASE OF RECURRENCE OF GRAVES’ DISEASE AND AUTOIMMUNE OPHTHALMOPATHY
Authors: Zemlyanitsyna O. V.
Published: July 2021

This article describes a clinical case of a relapse of Graves’ disease and autoimmune eye disease in men born in 1979, who was operated 2.5 years ago because of Graves’ disease. The differential diagnosis with autoimmune thyroiditis, showing the positive diagnostic value of antibodies to thyrotropin receptors was conducted. The dynamics of the patient’s condition on the background of the therapy was evaluated.
THE IMPACT OF ENDOGENOUS AND EXOGENOUS ESTROGENS ON METABOLIC DISTURBANCES IN FEMALE RATS WITH TYPE 2 DIABETES
Authors: Kiprich Tetiana , Gorbenko Nataliia , Borikov Oleksii , Ivanova Olha
Published: July 2021

It was investigated the impact of endogenous and exogenous estrogens on metabolic disturbances in female rats with type 2 diabetes. It was established that hypoestrogenic state increases insulin resistance, but doesn’t affect basal hyperglycemia, dyslipidemia and visceral obesity in diabetic female rats. Administration of compound PE0607 with selective estrogen-like activity as well as 17β-estradiol doesn’t influence hyperglycemia and insulin sensitivity, but suppresses dyslipidemia development. These results justify the perspectives of compound PE0607 use as a potential gender-specific agent for attenuation of cardiometabolic risk in type 2 diabetic women.
THE SCREENING IN SILICO OF POTENTIAL 11-HYDROXYSTEROIDDEHYDROGENASE 1 INHIBITORS
Authors: Lipson V. V. , Borodina V. V. , Redkin R. G. , Svetlichnaya N. V. , Zubatyuk T. A.
Published: July 2021

It was conducted the virtual screening by molecular docking with the program AutoDoc 4.2. for 27 000 structures of nitrogen and sulfur containing heterocyclic compounds has been carried out in order to identify of the enzyme 11β-hydroxysteroiddehydrogenase (11β-HSD1) inhibitors among them. It was established that spiro(pyrrolidin-3,2’-oxindoles), molecules of which have the residues of sulfurcontaining amino acids have been demonstrated in silico the greatest affinity to the specified target. We concluded of the expediency of these substances synthesis, and their anti-diabetic properties were experimentally estimated
USTIFICATION FOR IDENTIFYING SELENODEFITSITNYH AREAS IN UKRAINE AND ORGANIZATIONS CORRECTIVE MEASURES
Authors: Goncharova O. A.
Published: July 2021

The paper presents an analysis of the publications based on the results of experimental, clinical and epidemiological studies on the role of selenium in the normal functioning of the thyroid gland, efficacy of selenium in autoimmune thyreopatologii and modern understanding of its mechanisms. The results of research of level the selenium level in the hair of adolescents aged 14 — residents of some settlements Balakleysky and Chuguevsky areas of the Kharkiv region, was investigated. It was indicated the presence of selenium deficiency in these areas and the severity of which was the largest in the Chervonyy Donets village. When thyroid sonography revealed its increasing its volume in 64.3 % of cases.
ROLE OF THE FATHER FOR THE DEVELOPMENT AND STATE OF REPRODUCTIVE FUNCTION MALE OFFSPRING. NEGATIVE IMPACT OF PHYTOESTROGENS (literature review and own results)
Authors: Seliukova N. Yu.
Published: July 2021

Review of the literature devoted to the influence of some environmental factors in pre-consumated period on the father and the effects of these actions on his male descendants. It was found that rats’ male offspring who were born after father’s excessive consumption of phytoestrogens and with intact females, were with delay in sexual development. In adult male offspring who were born after father’s excessive consumption of phytoestrogens had observed hormonal imbalance, violation of sexual behavior. And also it was shown suppression generative function of testes and all these processes negatively effect of their reproductive potential.
THE LEVELS OF FOLIC ACID AND HOMOCYSTEINE IN THE BLOOD OF WOMEN WITH POLYCYSTIC OVARY SYNDROME AND THE DYNAMICS OF THESE INDICATORS DURING OF FOLATE THERAPY
Authors: Arkhypkina T. L. , Karachentsev Yu. I. , Bondarenko V. O. , Lyubimovа L. P.
Published: July 2021

It were examined 70 young women with PCOS. It was established, that these patients have lower levels of folic acid than healthy women, 47 % — reduction below reference values of norms, 52.8 % — hyperhomocysteinemia. Folic acid treatment at a dose of 5 mg/day helped to normalize its levels for 12 week therapy at that at women with normal body weight normalization was faster. The concentration of homocysteine during treatment as high as indicators of healthy women at patients with normal weight for 12 weeks of therapy, and at patients with obesity — for 24 weeks. Determination in blood levels of folate and homocysteine should be included a comprehensive examination of this category of patients, particularly at the stage pregravid period.
ADIPOCYTOKINE CHANGES IN PATIENTS WITH STABLE ANGINA AND OBESITY
Authors: Gabisoniia T. N. , Kravchun P. P. , Pashtiani R. V.
Published: July 2021

The article studied the effects of adipokines in the development of atherosclerosis in patients with stable angina and concomitant obesity. Established that dysfunction adipokinocytes exchange promotes hyperlipidemia and consequently the progression of atherosclerosis in patients with stable angina and obesity. According to the results of our study among the patients with stable angina with concomitant obesity the level of adiponectin is 17 % lower and visfatin level is 9.3 % higher in comparison to patients without obesity.
THE OBESITY IMPACT ON INFLAMMATORY MARKERS IN PATIENTS WITH STABLE ANGINA
Authors: Kovalyova Yu. A.
Published: July 2021

The work is based on the results of the survey of 47 patients with stable angina II–III functional class with obesity I degree. The dynamics of C-reactive protein, IL-lβ, IL-4 are described in patients with stable angina in association with obesity and without one. The character of the influence of obesity on the processes of inflammation in patients with atherosclerosis profile is presented. We estimated direct link between obesity and the severity of inflammation in patients with angina stable.
NEW POSSIBILITIES OF TREATMENT OF SUBCLINICAL TIEROTOXICOSIS IN SENIOR PATIENTS: PLACE AND ROLE OF PHYTOTHERAPY
Authors: Chernyavskaya I. V. , Cherniaieva A. A. , Dubovik V. N. , Romanova I. P. , Kravchun N. A.
Published: July 2021

The analysis of the clinical efficacy of the appointment of the dietary supplement «Thyreopharm®» to patients with subclinical thyrotoxicosis was carried out. It has been revealed that the dietary supplement «Thyreopharm®» contributes to the normalization of the hormonal thyroid status, reduces cardiac and vegetative symptoms, reduces the activity of the autoimmune process, thereby improving the morphological parameters of the thyroid tissue.
MICROBIOTA, AS A NEW TARGET OF PATHOGENETIC TREATMENT OF TYPE 2 DIABETES MELLITUS
Authors: Moskva K. A. , Urbanovych A. M. , Lapovets L. J.
Published: July 2021

General questions of the influence of intestinal microbiota on the pathogenesis of type 2 diabetes mellitus are considered in this article. It is explained that nutritional components affect the intestinal microflora, and its composition is directly associated with certain functional features. The study of the composition and functional properties of intestinal microbiota’s metabolites could allow optimization of the modern treatment approach, and also opens new possibilities for finding appropriate medicinal means or methods of influence.
QUALITY OF LIFE IN PATIENTS WITH DIABETES MELLITUS: THE FACTORS OF INFLUENCE AND THE WAY OF CORRECTION
Authors: Tykhonova T. M. , Smilka Y. N. , Khyzhnyak O. O.
Published: July 2021

Diabetes mellitus (DM) leads to a decrease in the quality of life (QOL) of patients compared with practically healthy individuals. Allocate nonspecific and DM specific factors, leading to a decrease in QOL. The main component of teaching diabetes patients, which should be aimed at the formation of a harmonious type of attitude towards their disease, is the training of self-monitoring of glycemia with individual devices (glucometers). According to production and operational characteristics, it is worthwhile to highlight the TM BIONIME and the TM GAMMA, users of which, thanks to modern equipment, acquire a «sense of confidence and security», which ultimately contributes to the improvement of QOL. The distributor of TM BIONIME and TM GAMMA products in Ukraine is «Dolphi-Ukraine».
RELATIONSHIP BETWEEN CARBOHYDRATE EXCHANGE PARAMETERS AND INTERLEUKIN-22 IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION WITH REGARD TO CONCOMITANT TYPE 2 DIABETES MELLITUS
Authors: Zhuravleva M. I. , Ryndina N. G. , Dunaeva I. P.
Published: July 2021

Worldwide, ischaemic heart disease is the single most common cause of death and its frequency is increasing. However, in Europe, there has been an overall trend for a reduction in ischaemic heart disease mortality over the past three decades [1]. Ischaemic heart disease now accounts for almost 1.8 million annual deaths, or 20 % of all deaths in Europe, although with large variations between countries [2, 3].Basu et al. found that althrought IL-22 was secreted by various types of cells, Th22 (CD4 + IL – 22 + T) cells were the critical source of IL-22 during the later stages of inflammation, indicating that Th22 may be essential for controlling chronic inflammation. The effector cytokine of Th22 cells is IL-22, which belongs to the IL-10 cytokine family and binds to the heterodimeric receptor complex consisting of the IL-10 receptor (IL-10R) β chain and IL-22R.
The role of plasminogen activator ingibitor type 1 in the development of endothelial disfunction in patients with acute myocardial infarction and type 2 diabetes mellitus
Authors: Minukhina D. V. , Babadzhan V. D. , Kravchun P. G. , Dunaeva I. P. , Minukhin D. V. , Krasnoyaruzhskiy A. G. , Yevtushenko D. A.
Published: July 2021

Acute myocardial infarction continues to occupy one of the leading places among the causes of mortality. Some indicators of endothelial dysfunction are also associated with a high risk of cardiovascular complications, which play a key role in the pathogenesis of cardiovascular complications, which makes it relevant to study the relationship between endothelial dysfunction markers and the development and progression of atherosclerotic vascular lesions. Dysfunction of the endothelial vasodilator system is accompanied by a decrease in the level of nitric oxide (NO), which is a characteristic feature of patients who are at risk of coronary artery disease, so coronary vasodilator dysfunction may involve prolonged progression of atherosclerosis and the frequency of cardiovascular events. The high risk of vascular accidents is an incentive to study the pathogenetic mechanisms of thrombotic formation in type 2 diabetes. Plasminogen activator inhibitor type 1, which is a member of the superfamily of serine protease inhibitors and the main inhibitor of fibrinolysis in the plasminogen activator system, plays a key role in the pathogenesis of arterial and venous thrombosis and, therefore, contributes to the occurrence of thrombotic events. The combination of acute myocardial infarction with type 2 diabetes mellitus is characterized by a significant increase in the content of the plasminogen activator inhibitor type 1 in serum compared with those without diabetes. As a result of the study, a close direct correlation between the increase of lipid, carbohydrate metabolism, hemostasis parameters proportional to the high content of the plasminogen activator inhibitor type 1 in serum of patients with acute myocardial infarction with concomitant type 2 diabetes mellitus was proved. The inverse correlation between the level of type 1 plasminogen activator inhibitor and the reduced content of nitric oxide synthase, which increases endothelial dysfunction and atherothrombosis in patients with acute myocardial infarction with concomitant type 2 diabetes mellitus, is proved.
Paracetamol (infulgan) for internal infusion — alternative opioids in the postoperative period
Authors: Fedorenko I. , Dubovik V.
Published: July 2021

The analgesic effect of the intravenous form of paracetamol (infulgan) in combination with nonsteroidal anti-inflammatory drugs was studied on the basis of the results of the 10-tone visual-analogue scale, data on mean dynamic pressure and pulse in patients in the early postoperative period. The influence of this technique on the level of pain impulse, indicators of the cardiovascular system, the development of dyspeptic phenomena and the temperature response are analyzed. A double infusion of paracetamol with a 6-hour interval and a three-fold administration of ketolong in a daily dose of 90 mg prevent the occurrence of severe and very severe pain. It has been established that patients with mild and moderate postoperative pain need effective administration of paracetamol and nonsteroidal anti-inflammatory drugs without the use of narcotic opioids.
The effect of long-term administration of chondroitin sulfate on the functioning of the reproductive system of male rats
Authors: Brechka N. M.
Published: July 2021

We assessed the effect of chondroitin sulfate in dose of 60 mg/kg during the period of spermatogenesis (the time between the first division of the spermatogonium and the sperm ejaculation from the testes), including the term of ripening in the epididymis — 70 days. Prolonged administration of chondroitin sulfate has no negative effect on the processes of spermatogenesis, especially on young cells of the spermatogenic epithelium — spermatogonia, and does not increase the number of tubules on the 12 stages of meiosis, that is, it does not reduce the reserve of spermatogenesis. Our findings testify, that the administration of chondroitin sulfate has no negative effect on the level of androgenic saturation and the functioning of the reproductive system of male rats.
FEATURES OF FORMATION AND TARGET-DIFFERENTIATED PSYCHOCORRECTION OF PSYCHOLOGICAL MALADAPTATION IN WOMEN WITH NON-CANCER THYROID DISEASE
Authors: Markova M. V. , Fedak B. S. , Varybrus O. V. , Mukharovska I. R. , Abdriakhimova Ts. B. , Kleban K. I. , Sapon D. M. , Lunov V. E. , Nikonov A. Yu. , Kravchun N. A.
Published: July 2021

In the study conducted assessment factors of formation psychological maladaptation in women with thyroid pathology. It was examined 59 women with hyperthyroidism, 54 – with hypothyroidism and 50 somatic healthy persons. Found basic psychological problems and their psychogenesis factors associated with endocrine disease in women with thyroid disorders, and peculiarities of emotional state depending on the type of hormonal dysfunction. Identified patterns of coping in patients with hypothyroidism and hyperthyroidism. Investigated specificity of response to disease among patients with different types of thyroid pathology. Characterized victim status in relation to the presence of chronic somatic pathology in women with thyroid disease. Studied quality of life of patients with hypothyroidism and hyperthyroidism. In the course of work, it was justified and identified the factors – components of psychological maladaptation of patients with thyreopathies variants of interaction of which determine the mechanisms of its development and clinical and psychological peculiarities of the course: psycho-biological, the basis of which is the effect of hormonal imbalance on the state of the nervous system, and secondary psychogenic that manifests in personally-psychosocial maladaptation of patients. On the basis of the obtained results, the hypothesis concerning the two-factor psychogenesis of psychological maladaptation in the specified contingent was formulated and proved, which became the basis for the development and implementation of endocrinological and medical-psychological practices of a target-differentiated bidecreative system of medical and psychological measures for patients with thyreopathies whose ultimate goal is not only elimination of existing psycho-emotional and personality deformations of patients, but also adaptation and acceptance of oneself in a situation of own illness, acceptance of the responsibility for oneself and one's health, the formation and maintenance of own preservation skills, which led to an increase in the effectiveness of somatotropic treatment and a significant improvement in the quality of life of patients.
Domain Heuristic Fusion of Multi-word Embeddings for Nutrient Value Prediction (Preprint)
Authors: Ispirova Gordana , Eftimov Tome , Koroušić Seljak Barbara
Published: July 2021

BACKGROUND

Being both a poison and a cure for many lifestyle and non-communicable diseases, food is inscribing itself into the prime focus of precise medicine, therefore knowing what is in our food has become utmost important. The monitoring of few groups of nutrients has become crucial for some patients, and with that methods for easing their calculations have emerged. The experts from fields concerned with this topic are constantly looking for ways to improve and ease the process of calculating nutrient values, which are missing for various reasons.

OBJECTIVE

The aim of this study was to explore the performance of a machine learning pipeline for predicting nutrient values from vector representations of text when using a domain-specific heuristic for combining uncontextualized word embeddings, which incorporates the quantities and the vector representations of the separate ingredients.

METHODS

Our proposed machine learning pipeline deals with macronutrient prediction based on learned vector representations from word and paragraph embedding algorithms on short text descriptions – recipe names. In this study we explored how the prediction results change when instead of using the vector representations of the recipe description, we use the embeddings of the list of ingredients. The nutrient content of one food – recipe depends on its ingredients and the quantities of those ingredients, therefore the text of the ingredients in contrast to the text in the short recipe description contains more relevant information for our task. Therefore, we define a domain-specific heuristic for merging the embeddings of the ingredients which combines the quantities of each ingredient as well in order to use them as features in machine learning models for nutrient prediction.

RESULTS

The results from the experiments indicate that the nutrient value prediction results improve when using the domain-specific heuristic for combining the separate ingredient embeddings, compared to when using conventional merging heuristics – sum and average of word embeddings. The best results, overall, were achieved using the Doc2Vec algorithm – which works on sentence level, for generating the single ingredient embedding, - which are multi-word embeddings. The prediction models for protein prediction were highly effective and yielded the highest accuracies (up to 97,98%), and the models for salt content prediction lacked in performance (up to 52,35% accuracy), this is due to the fact that salt content values on 100 grams are considerably low in comparison to the other nutrients of concern in this study.

CONCLUSIONS

Implementing a domain-specific heuristic for combining multi-word embeddings yields better results than using conventional merging heuristics, up to 60% more accuracy in some cases.
Towards a framework for evaluating the safety, acceptability and efficacy of AI systems for health: an initial synthesis (Preprint)
Authors: Morley Jessica , Morton Caroline , Karpathakis Kassandra
Published: July 2021

UNSTRUCTURED

The potential presented by Artificial Intelligence (AI) for healthcare has long been recognised by the technical community. More recently, this potential has been recognised by policymakers, resulting in considerable public and private investment in the development of AI for healthcare across the globe. Despite this, excepting limited success stories, real-world implementation of AI systems into front-line healthcare has been limited. There are numerous reasons for this, but a main contributory factor is the lack of internationally accepted, or formalised, regulatory standards to assess AI safety and impact and effectiveness. This is a well-recognised problem with numerous ongoing research and policy projects to overcome it. Our intention here is to contribute to this problem-solving effort by seeking to set out a minimally viable framework for evaluating the safety, acceptability and efficacy of AI systems for healthcare. We do this by conducting a systematic search across Scopus, PubMed and Google Scholar to identify all the relevant literature published between January 1970 and November 2020 related to the evaluation of: output performance; efficacy; and real-world use of AI systems, and synthesising the key themes according to the stages of evaluation: pre-clinical (theoretical phase); exploratory phase; definitive phase; and post-market surveillance phase (monitoring). The result is a framework to guide AI system developers, policymakers, and regulators through a sufficient evaluation of an AI system designed for use in healthcare.
Facilitators and Barriers to the Adoption of Telemedicine During the First Year of COVID-19: Systematic Review (Preprint)
Authors: Kruse Clemens , Heinemann Katharine
Published: July 2021

BACKGROUND

The virulent and unpredictable nature of COVID-19 combined with a change in reimbursement mechanisms both forced and enabled the rapid adoption of telemedicine around the world. Thus, it is important to now assess the effects of this rapid adoption and to determine whether the barriers to such adoption are the same today as they were under prepandemic conditions.

OBJECTIVE

The objective of this systematic literature review was to examine the research literature published during the COVID-19 pandemic to identify facilitators, barriers, and associated medical outcomes as a result of adopting telemedicine, and to determine if changes have occurred in the industry during this time.

METHODS

The systematic review was performed in accordance with the Kruse protocol and the results are reported in accordance with the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. We analyzed 46 research articles from five continents published during the first year of the COVID-19 pandemic that were retrieved from searches in four research databases: PubMed (MEDLINE), CINAHL, Science Direct, and Web of Science.

RESULTS

Reviewers identified 25 facilitator themes and observations, 12 barrier themes and observations, and 14 results (compared to a control group) themes and observations. Overall, 22% of the articles analyzed reported strong satisfaction or satisfaction (zero reported a decline in satisfaction), 27% reported an improvement in administrative or efficiency results (as compared with a control group), 14% reported no statistically significant difference from the control group, and 40% and 10% reported an improvement or no statistically significant difference in medical outcomes using the telemedicine modality over the control group, respectively.

CONCLUSIONS

The pandemic encouraged rapid adoption of telemedicine, which also encouraged practices to adopt the modality regardless of the challenges identified in previous research. Several barriers remain for health policymakers to address; however, health care administrators can feel confident in the modality as the evidence largely shows that it is safe, effective, and widely accepted.
ROY HARROD, ESTEBAN PÉREZ CALDENTEY
Authors: Bezares Arango Humberto
Published: July 2021

En los anales de la economía existen casos como el de Sir Roy Forbes Harrod (1900-1978), un notable economista que a pesar de su importancia para el estudio cuantitativo del crecimiento comparte el sino de Jean Babtiste Say cuyo legado es comúnmente reducido a una ley que lleva su apellido. En el caso de Harrod, sus aportes no sólo son frecuentemente reducidos al llamado “modelo Harrod-Domar”, sino que éste es “una clara tergiversación de su visión sobre la dinámica”.[1] No hay, pues, únicamente un interés erudito al estudiar su vida y obra, sino que hacerlo implica un esfuerzo de reivindicación de un economista que se resiste a los encasillamientos.

Roy Harrod (2019) de Esteban Pérez Caldentey forma parte de la serie de biografías intelectuales Great Thinkers in Economicsque a la fecha suma 27 volúmenes editados por el profesor Anthony Thirlwall de la Universidad de Kent. La mención no es gratuita: la conocida “Ley de Thirlwall” es una derivación del multiplicador del comercio exterior de Harrod, piedra de toque de la teoría keynesiana de economía “abierta”; hecho que habla, por un lado, de la vigencia de Harrod y, por el otro, de su innegable vínculo con J. M. Keynes...

[1]     En el original: “a clear misrepresentation of his views on dynamics” (Pérez, 2019, p. 2).
Reconstruyendo el “Proyecto Teotihuacán” del INAH, 1962-1964 (temporadas IV y V)
Authors: Medina-González José Humberto , Ortega-Cabrera Verónica
Published: July 2021

In a previous text, we addressed the archaeological seasons I, II and III that the Departament of Prehispanic Monuments of INAH implemented from the beginning of 1960 until September 1962 in the ruins of the ancient Teotihuacan city and that were the antecedent of the Seasons IV and V of the so-called “Teotihuacan Project”, executed between September 1962 and September 1964. The objective of this article is to expose the unpublished information of the "Proyecto Teotihuacan" that was consigned in the technical reports kept at INAH, as well as in the scarce texts that were published to bring to light the documentary sources that provide direct information from the protagonists of the project. All this documentation will give both researchers and the public the opportunity to evaluate -in a better informed way- the actions and contributions made during one of the most emblematic projects in the history of Mexican and Latin American archaeology. It is only in this way that it will be possible to understand the challenges faced by researchers, workers, public servants, and government institutions involved in carrying out these large-scale archaeological explorations and reconstructions. For the first time -more than half a century after the end of this megaproject- this article presents a systematic and complete overview of the information produced by this project. It is of utmost importance to recover this archaeological memory because it adds a better understanding of the narratives that were constructed by specialists in relation to the development of the pre-Hispanic society of Teotihuacan, and about the history of archaeology in this ancient metropolis.
El cuento de la menstruación
Authors: Garza Azucena
Published: July 2021

How is menstruation discussed? And how do we, females, read it in our own body? This essay walks through the warnings of a mother to her daughter, by the sharp pain and the experience of time in a menstruating body.
Un animal rabioso
Authors: De-Arrigunaga Macarena
Published: July 2021

An essay narrated from the intimacy which delves into the normalization of the menstruating people’s pain; the taught shame about our bodies, the violence caused by ignorance and the need to break that silence because if it does not have a name, it does not exist.
Menarquia, anarquía
Authors: Alzati Andrea
Published: July 2021

An autobiographical essay about menstruation, it explores the memorable events in the life of a menstruating person, the use of different methods to store the blood, and a textile art exercise to re-signify menstrual pain.
Palabras capaces de empoderar a niñas en la poesía del siglo XXI
Authors: Doporto Pilar
Published: July 2021

The founding of the Premio Hispanoamericano de Poesía para Niños in 2004, the publication of Digo de noche un gato by Maria Baranda (2006), and Hago de voz un cuerpo (2007, anthology directed by Baranda) mark the beginning of great literary quality poetry for children. Nowadays, there is a trend of books of poems for children that have a narrative thread and whose poetic voices and/or protagonists are girls. These girls use “words” to empower themselves. “Words” that seek to create a new reality, incantations, or known phrases to which one or few words are changed and their meaning is completely transformed. This message of brave protagonists, of course, reaches the girl readers.
Characteristics of Spanish citizen participation practices in science
Authors: Llorente Carolina , Revuelta Gema , Carrió Mar
Published: July 2021

A new regime of science production is emerging from the involvement of non-scientists. The present study aims to improve understanding of this phenomenon with an analysis of 16 interviews with Spanish coordinators of participatory science practices. The results indicate a majority of strategic and captive publics and point to communication as a key tool for the development of successful practices. Five key elements of the degree of integration required to develop a citizen participation in science practice were analysed: derived outputs, level of participant contribution, participation assessment, practice replicability, and participant and facilitator training. Proposals for strategies to remove barriers to citizen participation are the study's principal contribution.
El dispositivo emprendedor: Interpelación ética y producción de nuevos sujetos del trabajo
Authors: Santos Ortega Antonio , Serrano-Pascual Amparo , Borges Efrén
Published: July 2021

Asistimos actualmente a una multiplicación de prácticas de promoción del emprendimiento que, aunque desplegadas en diversos espacios y géneros, confluyen en la difusión de nuevos fundamentos de interpelación ética. El artículo propone el concepto foucaultiano de dispositivo como herramienta de acercamiento a estas prácticas. Tras describir el potencial heurístico de esta herramienta, se procede a aplicarla al estudio de la promoción de las éticas de la empreabilidad. Se destacan tres pilares que conforman dichos procesos de interpelación ética y que conforman un nuevo sujeto del trabajo: cultura de la evaluación y de la (auto)vigilancia; ethos de la responsabilidad y de la autonomía (repertorios de explicación y atribución de responsabilidades) y psicoempresarización del yo (capitalización de la subjetividad). Se identifican las tramas intertextuales que conforman el dispositivo emprendedor y que promueven una relación mercantilizada y productivista del sujeto consigo mismo.
Creativity and Myth Making in Moscow Texts by A.S. Dolmatov
Authors: Zhukova Aleksandra A.
Published: July 2021

The article deals with the problems of creativity and myth making in the Moscow texts by A. Dolmatov. The research is aimed at studying the authors ideas about his lyrical hero and the formation of the narrators self-portrait. A. Dolmatovs texts are dedicated to Moscow and the urban way of life, since it is the Moscow theme that is the sense-making component in the writers work. The article presents a brief history of rap poetry formation in Russia in the XXI century. The main features of problematics and poetics of A. Dolmatovs texts are analyzed. The task is to trace the evolution of the authors ideas on poetics and the meaning of rap as a genre of literature. The relationship of Dolmatovs lyrical hero with the city of roads, Moscow, defines the development of the authors work in alternative poetry of the 21 century.
Los afrodescendientes en la minería novohispana: ¿relegados o desconocidos? el distrito de Pachuca-Real del Monte en la segunda mitad del siglo XVIII
Authors: Navarrete Gómez Carlos David
Published: July 2021

Este artículo aborda el tema de la población afrodescendiente en la minería de la Nueva España en la segunda mitad del siglo xviii. Con base en dos censos parroquiales realizados en 1768, se documenta y analiza la destacada participación de dicho segmento social en la economíadel distrito de Pachuca-Real del Monte, importante zona productora de plata del centro de México. Si bien la presencia de los afrodescendientes en los espacios mineros novohispanos es un hecho reconocido por los historiadores, no se ha investigado con la amplitud y profundidad que amerita. A partir del estudio de caso seleccionado, el artículo busca contribuir a la correcta valoración de la agencia social y económica de la población afrodescendiente y a cuestionar la condición marginal a la que se le ha relegado, incluso respecto de otros grupos subalternos. También se propone coadyuvar al conocimiento y la comprensión de la minería novohispana desde perspectivas más amplias e integrales y, dada la relevancia del sector extractivo en el conjunto del virreinato, a construir un relato histórico más inclusivo de la sociedad y la economía del México colonial.
Espacios diferenciados y practicados a través de cinco imágenes inmaculistas: Santafé de Bogotá, siglos XVII y XVIII
Authors: Leal del Castillo María del Rosario
Published: July 2021

La imagen fue una de las estrategias usadas para explicar y expandir la devoción a la Inmaculada Concepción de María, debate teológico arduamente disputado durante los siglos xv a xvii. De acuerdo con el espacio en el que se encontraban dentro del conjunto franciscano, claustros o templo, las imágenes fueron parte de los mecanismos por medio de los cuales la orden trasmitió el capital cultural escotista, cuyo objetivo fue asegurar la correcta apropiación de la devoción y la participación histórica de la orden en dicha controversia.
English and American Travel Writing of the 1930s on Soviet Russia
Authors: Kabanova Irina V.
Published: July 2021

Starting with a survey of historical and ideological reasons for the unprecedented rise of Western interest in Russia after 1917 and especially after the Great Depression, the paper focuses on the travel books widely read on both sides of the Atlantic in the 1930s. The decade saw the blooming of travel prose in the English-speaking world, as well as the peak of enthusiasm for Russia during the XXth century. The paper attempts a closer look at the travel books on Soviet Russia, usually dismissed by critics as lacking in the quality of writing, too ideological. First the model of stereotypical book based on short Intourist tour is described (motive structure, prevailing parroting of Soviet propaganda clichés). Next follow the books produced by Western residents in the USSR, or persons who escaped Intourist surveillance and experienced some direct contact with Soviet people. They certainly look at Russia under the Western eye, but are able (to a different degree) to empathize with the drama and tragedy of Stalin’s Russia. From half-hearted account of “fellow-traveller” M. Hindus, the paper proceeds to fundamental “Assignment in Utopia” by E. Lyons, who turned from ardent Communist into highly argumentative critic of Soviet Russia, and to the unique project of writing a comic book about kolkhoz by E.M. Delafield, that resulted in a witty critique of Soviet aims and ways. In finding their way not just around Stalin’s Russia, but in providing the reader with the road to the authors’ inner selves, these books are still relevant today
Dream Collaborations: From the History of Eugene O’Neill’s Failed Projects
Authors: Zhamanova Amina A.
Published: July 2021

This article is focused on Eugene O’Neill’s failed artistic collaborations with outstanding directors, actors and singers. It is the first attempt, in the Russian theatre studies, to get to the truth behind the playwright’s unrealized tandem with the legendary opera singer Feodor Chaliapin. The creative destiny of O’Neill’s play Lazarus Laughed (1927) is tracked from the attempts to stage it in New York, Chicago, Berlin and Moscow, all the way to the long-anticipated premiere at the Pasadena Playhouse in Pasadena, California. Special attention is paid to the Kamerny Theatre shows in Paris and Buenos Aires. Also under scrutiny is the American playwright’s private correspondence — in particular, with literary agent Richard Madden, translator Alexander Berkman and theatre producer Kenneth Macgowan. Particular emphasis is put on the playwright’s work behind the scenes and his active contribution to the translation of his ideas to the stage. The article reflects O’Neill’s approach to picking actors for lead roles in the stage productions of his plays, and also gives a logical conclusion to his failed meeting with two-time Academy Award winner Spencer Tracy at the Tao House in Danville, California. The paper provides a review of Ingrid Bergman’s acting performance in the Anna Christie production (Lobero Theatre, Santa Barbara, 1941) and in Jose Quintero’s Broadway production More Stately Mansions (Broadhurst Theatre, New York, 1967) based on Eugene O’Neill’s late unfinished play.
Walter Scott and Washington Irving: On the History of Personal and Professional Relationship
Authors: Kolosova Ekaterina I.
Published: July 2021

Walter Scott and Washington Irving are prominent representatives of the Romantic era who were bound by both professional and friendly relations. Their friendship is a remarkable episode in the history of transatlantic literary contacts. In 1817, in Abbotsford, their personal meeting took place, which positively influenced Irving's career. Scott introduced his colleague to his friend John Murray, who was one of the most influential Scottish publishers of his day. Through this meeting, Irving became the first American writer to gain recognition in the UK. An idea of the relationship between Scott and Irving is given by their personal correspondence. Despite the fact that some letters have been lost or are currently in the hands of private collectors, there is enough published material to outline the main topics and interests that united these two writers. In an addendum to the article there are four letters in Russian translation, written in October–December 1819. They are especially noteworthy because they touch on a number of important aspects for Irving's career. In 1819, the American writer took the first steps towards publication in Great Britain and turned to Scott for help. From the master he received a professional assessment of his American editions of The Sketch Book. Scott gave advice on what books are best to publish for an English reader, as well as offered to take the editor post of an anti-Jacobin magazine. In addition, in these letters Scott introduced his American colleague to the intricacies of 19thcentury Scotland book-making and offered the most beneficial ways to communicate with publishers, which is also of interest from the point of view of the history of publishing in the 19th century Great Britain.
The Redemptive Sacrifice in J. Gardner’s Novel Grendel: An Analysis of the Novel’s Poetics in Light of Ritual-Mythological Criticism
Authors: Kalashnikov Anton A.
Published: July 2021

The paper presents an analysis of the novel Grendel (1971) by American writer J. Gardner (1933–1982) in light of M. Eliade’s, R. Girard’s and V. Toporov’s concepts of myth and ritual studies. Literary studies concerning the ritual-mythological aspect of the novel are reviewed in the article. The research hypothesis suggests that the key features of Gardner’s poetics can be systematically analyzed in the context of myth and ritual. Meanwhile, the bulk of previous research covering the issue tended to rely primarily on other analytical frameworks, like P. Bourdieu's sociology of literature (B. Ekelund) or the theory of intertextuality (H. Ellis, W. Ober), the myth and ritual theory playing a supplementary role. While placing myth and ritual theory at the core of the methodology, the present study highlights its two key categories singled out in line with B. Malinowski’s “functionalist” view of myth and ritual as two complementary aspects of the archaic culture — the “theoretical” one (myth) and the “practical” one (ritual). Here they are presented as the etyological nature of myth (i.e. its ability to view all phenomena as dependent on the primordial origin of the universe) and the redemptive sacrificial ritual. Accordingly, the etyologization of Grendel’s narrative and the presentation of the protagonist as an “emissary victim” (in Girard’s terms) are the specific features of Gardner’s poetics which the paper primarily addresses.
Efecto de las calizas agregadas a las pastas empleadas en la fabricación de productos cerámicos de construcción del área metropolitana de Cúcuta
Authors: Gelves Diaz John Freddy , Sánchez Molina Jorge , Díaz García Juan Isidro
Published: July 2021

El presente trabajo fue desarrollado para determinar los efectos generados por las calizas en las principales variables de control del proceso de producción de artículos cerámicos de construcción no esmaltados que se fabrican en la zona metropolitana de San José de Cúcuta, haciendo uso de la atmósfera oxidante en el proceso de cocción y la técnica de extrusión para su conformado. La investigación se llevó a cabo utilizando una muestra de arcilla y una muestra con alto contenido de sílice provenientes del municipio de Los Patios, Norte de Santander y rocas calizas provenientes del corregimiento de La don Juana jurisdicción del municipio de Bochalema. Se elaboraron diferentes mezclas aumentando el contenido de calizas a las cuales se les sometió al proceso de moldeo utilizando una extrusora de laboratorio manual, las probetas obtenidas fueron sometidas posteriormente a un proceso de secado en estufa de laboratorio hasta una temperatura de 100ºC, la cocción se llevó a cabo por un periodo comprendido entre 6 y 8 horas en un horno eléctrico en un rango de temperatura comprendido entre 980ºC y 1100ºC, aumentando en gradientes de temperatura de 20 grados centígrados. Al final del proceso se realizaron pruebas para determinar la absorción de agua de las probetas cocidas. La experimentación realizada permitió establecer que las piedras calizas empleadas y adicionadas a las arcillas de la región utilizando la técnica de extrusión como método de conformado contribuyen a una mayor fusión del material respecto a las mezclas tradicionales en adiciones en peso inferiores al 5%, siendo esto evidente a temperaturas superiores a los 1020ºC, como resultado de la mayor fusión bajo las condiciones establecidas, la adición de piedras calizas no mejora el proceso de control dimensional de los artículos cerámicos sometidos a cocción.Palabras clave: Absorción de agua, calizas, cerámica, contracción, eflorescencias, pastas.