bluuebunny/crossref_metadata_2025 huggingface dataset:
Association of APOE ɛ4 and Plasma p-tau181 with Preclinical Alzheimer’s Disease and Longitudinal Change in Hippocampus Function
Authors: Salami Alireza , Adolfsson Rolf , Andersson Micael , Blennow Kaj , Lundquist Anders , Adolfsson Annelie Nordin , Schöll Michael , Zetterberg Henrik , Nyberg Lars
Published: December 2021

Background: The Apolipoprotein E (APOE) ɛ4 allele has been linked to increased tau phosphorylation and tangle formation. APOE ɛ4 carriers with elevated tau might be at the higher risk for Alzheimer’s disease (AD) progression. Previous studies showed that tau pathology begins early in areas of the medial temporal lobe. Similarly, APOE ɛ4 carriers showed altered hippocampal functional integrity. However, it remains unknown whether the influence of elevated tau accumulation on hippocampal functional changes would be more pronounced for APOE ɛ4 carriers. Objective: We related ɛ4 carriage to levels of plasma phosphorylated tau (p-tau181) up to 15 years prior to AD onset. Furthermore, elevated p-tau181 was explored in relation to longitudinal changes in hippocampal function and connectivity. Methods: Plasma p-tau181 was analyzed in 142 clinically defined AD cases and 126 matched controls. The longitudinal analysis involved 87 non-demented individuals (from population-based study) with two waves of plasma samples and three waves of functional magnetic resonance imaging during rest and memory encoding. Results: Increased p-tau181 was observed for both ɛ4 carriers and non-carriers close to AD onset, but exclusively for ɛ4 carriers in the early preclinical groups (7- and 13-years pre-AD). In ɛ4 carriers, longitudinal p-tau181 increase was paralleled by elevated local hippocampal connectivity at rest and subsequent reduction of hippocampus encoding-related activity. Conclusion: Our findings support an association of APOE ɛ4 and p-tau181 with preclinical AD and hippocampus functioning.
A Mixed-Methods Study of the Impact of Mild Cognitive Impairment Diagnosis on Patient and Care Partner Perception of Health Risks
Authors: Kimmel Hannah J. , Levine Deborah A. , Whitney Rachael T. , Forman Jane , Plassman Brenda L. , Fagerlin Angela , Welsh-Bohmer Kathleen Anne , Reale Bailey K. , Galecki Andrzej T. , Blair Emilie , Langa Kenneth M. , Giordani Bruno , Kollman Colleen , Wang Jing , Zahuranec Darin B.
Published: December 2021

Background: Older patients (≥65 years) with mild cognitive impairment (MCI) are undertreated for cardiovascular disease (CVD). One reason for this disparity could be that patients with MCI might underestimate the chances of CVD and overestimate dementia. Objective: To compare conceptions of health risk between older patients with MCI and normal cognition (NC) and their care partners. Methods: We conducted a multi-center mixed-methods study of patient-care partner dyads completing written quantitative surveys (73% response rate; 127 dyads: 66 MCI and 61 NC) or semi-structured interviews (20 dyads: 11 MCI, and 9 NC). Surveys assessed two-year patient risks of dementia, heart attack, stroke, and fall. Interviews assessed similar health risks and reasons for risk perceptions. Results: On surveys, a similarly low proportion of MCI and NC patients felt they were at risk of stroke (5% versus 2%; p = 0.62) and heart attack (2% versus 0%; p = 0.99). More MCI than NC patients perceived dementia risk (26% versus 2%; p < 0.001). Care partners’ survey findings were similar. Interviews generally confirmed these patterns and also identified reasons for future health concerns. For both MCI and NC dyads, personal experience with cognitive decline or CVD (personal or family history) increased concerns about each disease. Additionally, perceptions of irreversibility and lack of treatment for cognitive decline increased concern about dementia. Conclusion: Less use of CVD treatments in MCI seems unlikely to be driven by differential perceptions of CVD risk. Future work to improve awareness of CVD risks in older patients and dementia risk in patients with MCI are warranted.
Chronic Beneficial Effect of Makeup Therapy on Cognitive Function of Dementia and Facial Appearance Analyzed by Artificial Intelligence Software
Authors: Tadokoro Koh , Yamashita Toru , Sato Junko , Omote Yoshio , Takemoto Mami , Morihara Ryuta , Nishiura Koichiro , Tani Tomiko , Abe Koji
Published: December 2021

Background: Makeup greatly impacts normal social lives but can also be a non-pharmacological form of therapy for dementia. Objective: To evaluate the therapeutic effect of makeup therapy. Methods: We carried out a prospective interventional study on female nursing home residents with dementia, focusing on the chronic therapeutic effect of makeup therapy. Thirty-four patients who received either only skin care (control group, n = 16) or skin care plus makeup therapy (makeup therapy group, n = 18) once every 2 weeks for 3 months were assessed. Results: Three months of makeup therapy significantly improved the Mini-Mental State Examination (MMSE) score compared with control patients (*p < 0.05). Artificial intelligence (AI) software revealed that the appearance of age decreased significantly in the makeup group compared with the control, especially among patients without depression (*p < 0.05). Furthermore, a larger AI happiness score was significantly correlated with a greater improvement of ADL in the makeup therapy group (r = 0.43, *p < 0.05). Conclusion: Makeup therapy had a chronic beneficial effect on the cognitive function of female dementia patients, while the chronic effect of makeup therapy on facial appearance was successfully detected by the present AI software.
Bibliometric Analysis of Nursing Informatics Research
Authors: Liu Jialin , Liu Siru , Shi Qingke , Wang Miye
Published: December 2021

This study aims to provide a bibliometric overview of research at nursing informatics and understand the state in nursing informatics in the last ten years. We used the Web of Science to extract relevant literature published from 2009 to 2018. A total of 455 articles were retrieved and analyzed. The total of the top 5 institutions, countries, journals was discussed. This study will help researchers to understand trends and the situation in nursing informatics research.
A Proposed Approach to Investigate Whether Postgraduate Health Care Management Education in Australian Universities Facilitates the Development of Informatics Competencies
Authors: Brommeyer Mark , Mackay Mark , Liang Zhanming , Schaper Louise , Balan Peter
Published: December 2021

Competencies have emerged as being important in healthcare. AIDH has health informatics competencies and ACHSM has health service management competencies but as health care is rapidly changing, it is important that the required competencies continue to evolve. The aim is to investigate whether postgraduate health care management education in Australian universities facilitates the development of informatics competencies. The proposed approach followed the NWCPHP ‘Steps Used to Effectively Map Preexisting Courses to Competency Sets’ to map the health informatics competency statements against the ACHSM accredited and RACMA recognised, postgraduate health care management programs offered domestically in Australia. The initial results show that only 10% of the AHICF competencies were fully addressed, 12% of the AHICF competencies were mostly addressed, 28% were partially addressed, and 50% of the AHICF competencies were not addressed at all. The proposed course competency mapping approach demonstrates that there is a need to revisit the informatics competencies taught in postgraduate health care management programs in Australia.
Enabling Digital Professionalism: Analysis of the Australian and United Kingdom Nursing Education Standards
Authors: Mather Carey
Published: December 2021

Growth in use of digital technology for leisure and learning has created challenges for healthcare environments globally. Its rapid evolution in nursing continues to outpace the more sporadic updating of registered nurse standards, guidelines and codes of professional conduct. Revised standards in Australia and the United Kingdom establish the contemporary governance context for the educational preparation of registered nurses. A document analysis of these standards reveals an omit of guidance regarding the expected knowledge, skills, attitudes and behaviour of undergraduate nurses about when and how to access and use of digital technology on campus, and during work integrated learning. Documents governing nursing do not currently foster the development of digital professionalism, an essential component of professional identity formation, which is necessary to acquire prior to graduation as a registered nurse.
Development of Nursing Informatics Competencies Evaluation Index System of Clinical Nurses
Authors: Chen Yuan , Yan Lijuan , Zheng Weiliang , Lin Bixia , Wu Linjing , Wu Zhimin , Chang Polun
Published: December 2021

For lack of effective and reliable assessment tools of nursing informatics competencies (NIC), we used literature research method, nominal group technology (NGT) and delphi technique to construct an evaluation index system of NIC for clinical nurses, which can provide reference for establishing a training system of talents of nursing informatics.
Pilot Research to Develop a Nursing Digital Health Capability Framework in Chile
Authors: Benavente Antonia , Urra Eugenia , Hullin Carol , Almond Helen
Published: December 2021

The Global Digital Health Strategy emphasizes digital health workforce development to reach a sustainable health system. In Chile, a digital health capability framework to support the transition towards digital health and workforce development is still missing. A survey will be applied at a national level. The Development of a Chilean Nursing Digital Health Capability Framework will identify the capabilities of nurses in digital health innovation and improve the quality and safety of healthcare nationwide.
Assessment of the Chinese Literature for Nursing Informatics Education Initiatives
Authors: Liu Siri , Zheng Tao , Fang Jinbo , Liu Jialin
Published: December 2021

The purpose of this study is to understand the state of the literature on nursing informatics education in Mainland China. We used the CNKI database (China National Knowledge Infrastructure) to extract all papers of nursing informatics education from 2009 to 2018. 20 high-frequency keywords, a co-word matrix, and three research themes were conducted on the 18 papers. These results can be used to improve our understanding of nursing informatics education in Mainland China.
Web-Based Text Analysis of the Patient Safety Concerns of Various Healthcare Stakeholders
Authors: Cho Insook , Lee Minyoung , Kim Yeonjin
Published: December 2021

Patient safety is a fundamental aspect of the quality of healthcare and there is a growing interest in improving safety among healthcare stakeholders in many countries. The Korean government recognized that patient safety is a threat to society following several serious adverse events, and so the Ministry of Health and Welfare of the Korean government set up the Patient Safety Act in January 2015. This study analyzed text data on patient safety collected from web-based, user-generated documents related to the legislation to see if they accurately represent the specific concerns of various healthcare stakeholders. We adopted the unsupervised natural language processing method of probabilistic topic modeling and also Latent Dirichlet Allocation. The results showed that text data are useful for inferring the latent concerns of healthcare consumers, providers, government bodies, and researchers as well as changes therein over time.
Mapping a Strength-Oriented Approach to a Standardized Terminology: A Case Study
Authors: Gao Grace , Austin Robin R , Kirk Laura N , Holland Diane E , Bruhjell Candice , Monsen Karen A
Published: December 2021

As a new era of healthcare advocates a more valuable and intelligent approach to care management and delivery based on values and outcomes, shifts toward risk management to boost performance should be considered that encompass the capitalization of health assets or health strengths. To make full use of individuals’ or populations’ health assets, data capture and representation are needed. This paper uses a strengths-oriented case study mapped to an inter-disciplinary standardized terminology, the Omaha System, to illustrate and compare the conventional problem-based approach to care management with the strengths-oriented approach to care that demonstrates whole-person data capture of an individual’s health and health assets leveraged to promote health values and performance. The Omaha system provides a standardized framework to organize the concepts of all of health from a whole-person perspective for documentation to enable data analysis, interoperability, and health information exchange.
The Cost of Patient Education on a Post-Partum Unit in an Acute Care Setting
Authors: Jost Audrey , Velez Kim , Fawns Elle
Published: December 2021

Four years post-implementation, an interactive patient care system is slated for decommissioning in two hospitals. A team of experts was tasked with evaluating whether to replace or remove the functionalities of this system and the cost associated with either. The largest effects noted were the financial burden and the patient education. The cost to substitute video education with nursing time spent in patient education was determined to not be cost-effective.
Website for Women Who Abuse Opioids: What Are the Essential Components?
Authors: Choi Jeeyae , Kim-Godwin Yeounsoo
Published: December 2021

Studies indicate opioid prevention programs should be designed differently for men and women. Since a website is an effective means of providing behavioral interventions, tailoring one to meet the specific needs of women is a logical step in assisting them to overcome opioid misuse. We identified essential components for inclusion in a website following a community engagement project.
Study of Sharing Patient Information by Nurses Between Inpatient and Outpatient Wards in Japan
Authors: Nishida Natsuko , Hikita Tomoko , Iida Megumi , Yamamoto Goshiro , Kuroda Tomohiro
Published: December 2021

Shortening hospital stays increases communication needs between nurses in inpatient and outpatient wards. Smooth information sharing is required to reduce the workload of nurses and improve the quality of patient care. However, electronic medical records (EMR) system does not have sufficient functions to support information sharing between wards, because EMR has been developed mainly for recording. This study led to three improvements; unified communication tool, common patient list linked to EMR, and outpatient nursing diagnosis.
Development of an eHealth Nursing Intervention on Self-Care to Prevent Diabetic Foot in Rural Mexico: A Pilot Test
Authors: Ramírez-Pérez Edgar Mauricio , Moreno-Tochihuitl Maricarmen , Ricardez-Ramírez María del Rosario , Block Lorraine , Peltonen Laura-María , Castro-Fernández de Lara María del Pilar , Lozada-Perezmitre Erika
Published: December 2021

Diabetic foot affects nearly 6% of people living with Type 2 diabetes (T2D). It is also the most common complication of T2D and is associated with infection, ulceration. eHealth facilitation of Non-communicable diseases management has the potential to increase self-care and engage patients. The aim of this study is to develop an eHealth intervention to prevent diabetic foot.
Impact of Electronic Medical Records Within the Maternity Environment: An Ethnographic Exploration of Midwifery Practice
Authors: Craswell Alison , Kearney Lauren , Mcatee Jenni , Hadland Mariann , Smyth Wendy , Nagel Cate
Published: December 2021

Integration of care through digitalisation of paper records is important for childbearing women who may see multiple clinicians both within the hospital and the community. It is important that in the implementation of an EMR, the established benefits of a paper and handheld records are transferred and not lost. Acceptance and positive use of digital records in maternity settings has occurred despite concerns regarding workload interrupting women centred care.
Prevalence, pattern and predictors of work-related musculoskeletal disorders among oil workers in Nigeria
Authors: Omojunikanbi Oluwagbejami Alfred , Akinpelu Aderonke Omobonike , Ekechukwu Echezona Nelson Dominic
Published: December 2021

BACKGROUND: Work-related musculoskeletal disorders (WMSD) account for a loss of GDP in most countries. The oil sector is the largest and most economically relevant industry in Nigeria, yet the impact of WMSD on workers in this industry is unknown. OBJECTIVE: To assess the prevalence, pattern and predictors of WMSD among oil workers in Nigeria. METHODS: This exploratory study was conducted in oil producing companies in Nigeria. Nordic Musculoskeletal Questionnaire was used to assess WMSD, while risk factors and demographic variables were obtained through an interview. Obtained data were analysed using descriptive statistics, Chi-square and logistic regression at α=0.05 RESULTS: A total of 198 (138 male, 60 female) oil workers aged 40.3±10.1 years participated in this study. The prevalence of WMSD was 88.8%, and was most common around the low-back (51.5%), and neck (44.4%) regions. There was a significant association between WMSD and each of duration of service (X2 = 45.44, p = 0.020), awkward neck postures at work (X2 = 12.46, p = 0.006), inadequate training on injury prevention (X2 = 11.98, p = 0.007), and continuing to work while feeling discomfort (X2 = 10.83, p = 0.013). Post-hoc analysis revealed that being a male oil worker (OR = 1.17, p = 0.037) and continuing to work while feeling discomfort or pain (OR = 2.23, p = 0.048) were the significant predictors of WMSD. CONCLUSIONS: Approximately nine in every ten oil workers in Nigeria have a WMSD. Male gender and work persistence amidst discomfort or pain are the predictors of WMSD among oil workers in Nigeria. Ergonomics training and evaluation programme is recommended for workers in this industry.
Concerns and mental health of teachers from digitally underdeveloped countries regarding the reopening of schools after the first wave of the COVID-19 pandemic
Authors: Milić Sanja , Marić Nada
Published: December 2021

BACKGROUND: Torn between the decision to return to school classrooms or continue holding online classes during COVID-19, teachers around the world feel great uncertainty. OBJECTIVE: Bearing in mind that the study of mental health during the pandemic is of great importance for vulnerable categories, and given the role of teachers in society, the aim of this research is to assess teachers’ concerns and anxiety before the start of the school year, and also to examine the factors related to them and propose measures in line with the results. METHODS: The study was conducted as a cross-sectional study before the start of the 2020/2021 school year. The research sample consisted of 286 teachers. For the purposes of this research, a special questionnaire was constructed consisting of a general questionnaire and a Generalized Anxiety Disorder 7-item scale (GAD-7). RESULTS: The strongest predictor of a teacher’s answer that they were concerned about the reopening of schools was their concern for their own life and health and for the life and health of their family members, followed by the amount of information received about COVID-19, and, finally, older age. Only 2% of teachers had mild anxiety. CONCLUSIONS: This research indicated that it is necessary to examine in more detail the degree of teachers’ concern and its impact on their functionality and work process. It is also necessary to repeat the research on the mental health status of teachers and implement procedures in the form of a regular screening program of the mental health status of teachers or implement procedures of support in concern management.
Exergaming to improve physical, psychological and cognitive health among home office workers: A COVID-19 pandemic commentary
Authors: Sadeghi Hassan , Jehu Deborah A.
Published: December 2021

BACKGROUND: The COVID-19 pandemic has resulted in increased sedentary behaviour and poorer health among office workers. Exergaming is a technology-driven mode of exercise that can improve health while physically distancing. OBJECTIVE: The purpose of this commentary was to explain the benefits of exergaming on physical function, psychological health, and cognition among office workers. RESULTS: Exergaming improves these health outcomes, reduces pain, and decreases the risk for chronic disease. It is easily accessible on smart devices and can be performed both indoors and outdoors. CONCLUSIONS: Twenty-one minutes of exergaming per day can improve health outcomes and reduce the risk of pain and disease. Employers and policy-makers should consider promoting exergaming among office workers.
ПЕДАГОГИЧЕСКИЙ ПОТЕНЦИАЛ «ДОКУМЕНТАЛЬНОГО ТЕАТРА» В СОВРЕМЕННОЙ ТЕАТРАЛЬНОЙ ШКОЛЕ
Authors:   Алтайский государственный институт культуры, Гарибов Руслан
Published: December 2021

Данная статья посвящена исследованию одной из образовательных технологий современной театральной школы – «методу документального театра». Обобщив практический опыт, автор приходит к следующим выводам: документальный театр позволяет быстрее находить острые социальные проблемы, помогает личностно погрузиться в изучение повседневности и человека, начать осознанно анализировать существующие проблемы, тем самым способствует формированию активной гражданской позиции будущих актёров и режиссёров.
ANALYSIS OF THE RESULTS OF PERFORATED DRAINAGE PIPELINES CALCULATION IN THE PRESENCE OF TRANSIT FLOW RATE
Authors: Kravchuk Andriy , Kravchuk Oleksandr
Published: December 2021

A method of calculating the error that occurs when determining the flow rate in the final section of the pressure perforated drainage pipeline when it passes transit flow rate, based on the analysis of differential equations describing the fluid motion with variable flow rate in such pipelines is proposed in the paper. The analysis is presented in dimensionless form. The impact of transit flow on the main flow is estimated using the values ​​of the drainage pipeline resistance coefficient ζl and the generalized parameter of the perforated drain A, which takes into account its constructive and filtration characteristics. The obtained calculation formulas are quite simple and easy to use. The proposed method allows to perform calculations of drainage pipelines that operate in the presence of transit flow rate, according to the method of these pipes calculation that dispose drain water without passing transit. Herewith, the possible error, which includes in the calculation results, determines. To illustrate the obtained dependences, the corresponding graphs are given in the paper. The results of the analysis allow to determine the limits within which a simplified method of calculating these pipes can be used and the error, that occurs, can be estimated
CARBONIZATION OF CONCRETE AND CORROSION OF REINFORCEMENT OF REINFORCED CONCRETE STRUCTURES OF UNDERGROUND SEWERAGE SYSTEMS
Authors: Makarenko Valeriy , Gots Volodymyr , Khomutetska Tetiana , Makarenko Yulia , Arhatenko Tetiana , Prybytko Iryna , Panchenko Olena
Published: December 2021

The process of carbonization of concrete with different ratio of water to cement (W/C) was studied, and the influence of the environment on corrosion damage of reinforced concrete reinforcement was studied. The results of the study of carbonization of concrete on specially prepared model samples of concrete with a size of 250x250x250 mm with an exposure period in NACE solution for 500 days without external load are presented. Measurements of corrosion damage of reinforcing rods, which were placed inside concrete cubes, were performed. The method of estimating the amount of carbonization of concrete and corrosion of reinforcement is described in detail in known scientific papers. The obtained data testify to the active carbonization of concrete during the whole exposure period of the samples in NACE solution, however, concrete prepared at the ratio W/C = 0.5 and 0.6 is particularly significant in terms of carbonization intensity. Concrete with a ratio of W/C = 0.7 is less susceptible to damage. Moreover, a similar trend is observed for corrosion of fittings. This is due to the fact that the increase of the aqueous medium in the concrete mass facilitates diffusion processes of delivery to the reactive zone of chemically aggressive ingredients such as carbon dioxide, chloride ions, hydrogen, sulfur, sulfate ions, various types of bacteria and the like. The kinetics of concrete carbonization and corrosion of reinforcing bars in chemically aggressive NACE medium depending on the exposure period of the samples in the model solution was experimentally studied. It is established that with the increase of the water-cement ratio W/C from 0.5 to 0.7, the depth of carbonization and the layer thickness of corrosion products increase sharply. The flooding of the surface layers of the reinforcement and their strong embrittlement in the process of long-term operation of the reinforcement in the structure of reinforced concrete, which causes a decrease in crack resistance in general of reinforced concrete structures. The degradation of reinforcing steel during long-term operation in aggressive environments, which leads to premature corrosion damage to the reinforcement with subsequent destruction of the structure, was investigated experimentally with the involvement of high-precision metallographic equipment.
Contact-centers and Artificial Intelligence
Authors: Raynus Mark
Published: December 2021

Ruslan Makrushin talks to “Intellectual Archive” about trends in the advanced contact centers market, the future of their architecture and the application of the artificial intelligence
Dietary patterns of Polish seniors in retirees’ households
Authors: Stoś Katarzyna , Ołtarzewski Maciej , Rychlik Ewa
Published: December 2021

Background. About 7 million people in Poland receive pensions. The amount of benefits paid to pensioners is reflected in the income at their households and expenses, including food expenses.
Objective. The aim of the study was to evaluate the dietary patterns of Polish seniors in the retirees` households on the basis of an analysis of food consumption and energy and nutrient intake.
Material and method. Food consumption evaluation was based on household budget survey conducted by Statistics Poland in 2019 throughout the whole country. Energy and nutrient intake were calculated using the conversion factors.
Results. The consumption of unprocessed red meat in retirees’ households was 1.83 kg/person/month, meat products – 2.90 kg and kitchen salt – 0.24 kg. 6.52 kg of vegetables and 5.99 kg of fruit were consumed per person per month. The mean energy intake in members of these households was 2387 kcal/day. The proportion of energy from fat was high – 36.6%. 14.2% of energy was derived from protein and 49.6% from digestible carbohydrates. The share of animal fat (55.0 g) was higher than vegetable fat (43.7 g). It was associated with a high percentage of energy from saturated fatty acids – 13.4%. The content of polyunsaturated fatty acids was less than half of the saturated fatty acids. Calcium and vitamin D intake was low (658 mg and 3.8 μg respectively).
Conclusions. Red meat, processed meat and salt consumption by seniors was too high in relation to the nutritional recommendations. Vegetables and fruit were consumed in amounts that are recommended. Seniors diet was improperly balanced, e.g. due to the high percentage of energy from fat, including saturated fatty acids. However, the intake of polyunsaturated fatty acids was low. Calcium and vitamin D intake was lower than Reference Intakes.
Apresentação
Authors: Rodrigues Thiago
Published: December 2021

Apresentação
PERSPEKTIF FETHULLAH GÜLEN TENTANG DIALOG DAN TOLERANSI SEBAGAI RESOLUSI KONFLIK
Authors: Setiadi Ozi
Published: December 2021

Konflik menjadi sesuatu yang tidak dapat dihindari bila tidak ada kesepahaman dan saling pengertian terhadap sebuah permasalahan. Ini kemudian memunculkan berbagai teori yang dicetuskn oleh para cendekiawan berkaitan dengan upaya yang harus dilakukan oleh masyarakat guna menyelesaikan konflik tersebut. Tulisan ini menjelaskan tentang bagaimana perspektif Fethullah Gulen sebagai sosok yang cinta damai dalam mengembangkan dialog dan toleransi sebagai resolusi konflik. Gulen berpendapat bahwa dialog dan toleransi bagaikan dua sisi mata uang yang tidak dapat dipisahkan. Dialog menjadi media yang menjembatani kerjasama peradaban, persaudaraan dan saling kesepahaman antara satu dengan lainnya, serta menghargai atas nilai-nilai yang diyakini bersama. Dialog menjadi sebuah bentuk yang menunjukkan kemoderatan yang tidak eksklusif dan terbuka terhadap pendapat berbagai kalangan. Sedangkan toleransi menjadi media yang sangat penting, bila sebuah dialog tidak menghasilkan kesepakatan atau kesepahaman, maka toleransi adalah jalan yang terbaik. Ini disebabkan toleransi menjadi sebuah cara untuk menahan diri dari terjadinya sebuah konflik. Dialog dan toleransi, meski kehadirannya sangat penting guna menciptakan perdamaian, namun hal ini juga memiliki hambatan khususnya bagi umat Muslim. Hambatan tersebut menurut  Gṻlen diantaranya adalah ketidakpahaman umat Muslim itu sendiri dengan Islam saat ini, selain ingatan kolektif historis umat non Muslim, Kristen, tentang tragedi berdarah yang menimpa mereka atas perlakuan umat Muslim.
Deneysel Kafa Travması Oluşturulan Sıçanlarda Nöronal Hasarı Belirlemede Alfa-sinüklein Protein Etkinliğinin Araştırılması
Authors: ALTINKÖK ŞENTÜRK Buşra , ÇIKRIKLAR Halil İbrahim , DURAK Vahide Aslıhan , AYDİN Birnur , ARMAGAN Erol
Published: December 2021

Çalışmamızın amacı deneysel olarak hafif travmatik beyin hasarı oluşturulan kafa travması modelinde sıçanlardan alınan serum örneklerinde alfa-sinüklein (α-syn) düzeyinin akut dönemde travmatik beyin hasarını göstermede tanısal değerini araştırmaktır. Çalışmamızda toplam 40 adet erişkin Spraque-Dawley cinsi sıçan kullanılmıştır. Denekler kontrol grubu (n=8) ve 4 ayrı deney grubu (n=8) olarak 5 gruba ayrıldılar. Çalışmamızda Marmarou ve ark.’nın tanımladığı model modifiye edilerek uygulandı. Bu modelde farklı yüksekliklerden farklı ağırlıklarda bilyeler serbest düşme yöntemiyle bırakılarak sırayla 0,05, 0,1, 0.2 ve 0,4 Newton şiddetinde travma oluşturulması hedeflendi. Travmanın indüksiyonundan 2 saat sonra sıçanların kalbinden alınan kanlarda α-syn düzeyi araştırıldı. Kontrol grubuna göre kan α-syn düzeyleri ölçüldüğünde, 0,05 ve 0,2 Newton şiddetinde travma oluşturduğumuz gruplarda düşüş görülmüştür. Daha şiddetli travma oluşturduğumuz (0,2 Newton) grup, az şiddetli oluşturduğumuz gruba (0,05 Newton) göre anlamlı olarak daha düşük bulunmuştur. Sonuç olarak farklı şiddetlerde kafa travması oluşturduğumuz sıçanlardan ikinci saatte alınan kan örneklerinden α-syn düzeylerinde anlamlı bir yükselme görülmemiştir. Aksine iki travma grubunda kontrol grubu ile kıyaslandığında düşme görülmüştür. Bu sonuçlar kafa travması sonrası ikinci saatte alınan kanlardan bakılan α-syn düzeyinin TBY için erken dönemde tanısal olarak etkin olmadığını düşündürmektedir.
Beyin Tomografi Yorumlamada Acil Tıp Asistan ve Uzmanları ile Radyologların Karşılaştırılması
Authors: SIR Zeynep Nazlı , İŞLER Yeşim , KAYA Halil
Published: December 2021

Çalışmanın amacı, hastanemiz acil servisine başvuran kafa travmalı çocuk hastalara çekilen kranial bilgisayarlı tomografi (BT) görüntülerinin, acil tıp asistan (ATA) ve acil tıp uzman (ATU) hekimlerinin yaptığı yorumun, radyoloji uzmanı (RU) tarafından yapılan yorum ile uyumluluğunu karşılaştırmaktır. 2 aylık dönemde Yüksek İhtisas Eğitim ve Araştırma Hastanesi acil servisine kafa travması ile başvuran ve kranial BT görüntülemesi yapılıp, bir radyoloji uzman hekimi tarafından raporlanmış kranial BT görüntüleri kullanılarak yapıldı. Çalışmaya 10 ATU ve 2 yılını doldurmuş 10 ATA gönüllü oldu. 126 hastanın kranial BT’si randomize olarak dağıtılarak ayrı ayrı değerlendirmesi istendi. RU hekiminin sonuç raporları altın standart kabul edildi. Fraktür bölgelerinde ATU ve ATA’nın RU ile uyumlu olduğu görülmektedir (κ=0,58 κ=0,68). Fraktür tipinde ATU ve ATA’nın RU ile uyumlu olduğu görülmektedir ( κ=0,58 κ=0,68). Kanama bölgesinde ATU ve ATA’ların RU ile uyumunun orta düzeyde olduğu görülmektedir (κ=0,41 κ=0,47). Kanama tipinde, ATU ve ATA’nın RU ile uyumlu olduğu görülmektedir (κ=0,54 κ=0,60). Genel olarak acil tıp asistan ve uzmanlarının kanama, fraktür ve diğer bulguları saptamada radyoloji ile uyumunun iyi düzeyde olduğu görüldü. Kanama, fraktür tipi ve lokalizasyonunda uyuma bakıldığında orta-iyi derecede olduğu görüldü. Acil tıp asistanlarının uzmanlara göre uyumunun daha yüksek olduğu görüldü.
Pobreza e desigualdade social nas escolas do núcleo rural do município de Paraú-RN
Authors: Rocha Magna Maria da Conceição
Published: December 2021

Falar sobre a pobreza e desigualdade social é um desafio que nos remete a vários aspectos da existência humana e do ser social. Entendemos que a superação da pobreza é ou está condicionada a evolução do ser humano quanto à aquisição e evolução como ser social. Diante do exposto, o presente artigo, tem como questão norteadora: Qual o nível de pobreza e desigualdade social nas escolas da zona rural do município Paraú? Tem como objetivo analisar o nível de pobreza e desigualdade social nas escolas do núcleo rural do município de Paraú – RN e apresentar suas causas e consequências. Para isto, foi realizada uma análise quantitativa de levantamento de dados, utilizando um questionário misto (questões abertas e fechadas) composto de 7 (sete) questionamentos para os segmentos: escola e comunidade escolar. Com base nos dados colhidos identifica-se que a maior parte dos entrevistados se declara pobre e não conhece o conceito de desigualdade social. Chega-se à conclusão de que a pobreza e a desigualdade social nas escolas in loco, são fatores de exclusão política e social, demonstrando a necessidade de políticas públicas que atendam a população presente nestas escolas.
Jesu li zadaci iz matematike na natjecanjima za osnovnu školu u RH preteški ? -Od Školskog natjecanja do JBMO-
Authors: Ostojić Ana
Published: December 2021

Analizom riješenosti zadataka na svim razinama natjecanja proteklih godina u Republici Hrvatskoj, a konkretno ću se osvrnuti na školsku godinu 2018./2019., lako je detektirati one zadatke koje su učenici manje uspješno riješili. Poseban osvrt sigurno zaslužuje Županijsko natjecanje. Mnogi će se mentori složiti da su ti zadaci preteški i da učenici zbog toga odustaju od natjecanja iz matematike. Je li to doista tako ili postoje i drugi razlozi zbog kojih učenicima ponestaje motivacije? Ponestaje li zaista motivacije onima najuspješnijima?! S druge strane, što takve učenike očekuje na Međunarodnim natjecanjima i kako se za natjecanja pripremaju njihovi vršnjaci izvan granica RH? Jednako tako, je li važna i motivacija učitelja za rad s tako izrazito nadarenim učenicima? Jesu li mentori spremni na izazove koje pred njih stavlja nadareni „osmaš“ tijekom priprema npr. za Juniorsku balkansku matematičku olimpijadu? Trebamo li spustiti razinu očekivanja od naših učenika ili dopuniti razine natjecanja koje smo tijekom godina izgubili? Brojna pitanja traže odgovor, ali i suglasje svih mentora kako bismo zajedno s Državnim povjerenstvom uz podršku Agencije za odgoj i obrazovanje i Ministarstva znanosti i obrazovanja sustav natjecanja unaprijedili i uskladili s očekivanjima učenika i mentora, ali i s međunarodnom razinom u kojoj Republika Hrvatska već odavno u kontinuitetu ima zapažene rezultate.
Geometrijska definicija morfnih brojeva
Authors: Marohnić Luka , Kovačić Bojan
Published: December 2021

U članku se najprije izlažu geometrijske definicije zlatnoga reza i plastične konstante te se pokazuje kako su to jedini morfni brojevi. Zatim se definira zlatna dekompozicija reda n > 2 zadane dužine na n dijelova. Na koncu se pokazuje da je baza zlatne dekompozicije nužno morfni broj te da zlatna dekompozicija postoji ako i samo ako je reda 2 ili reda 3.
Microsatellite DNA heterozygosity and weight performance in Southern meat cattle breed heifers
Authors: Kramarenko A. S. , Kramarenko S. S.
Published: December 2021

The purpose of this study was to determine whether heterozygosity (assessed using microsatellite genotypes) was correlated with the body weight of heifers from birth to 18 months. The study was conducted on the heifers’ herd of the Taurian intra-breed type Southern meat cattle breed at Askaniiske State Research Enterprise (Ukraine, Kherson Region). During the study, we used ten microsatellite loci recommended by International Society for Animal Genetics (ISAG) TGLA227, BM2113, TGLA53, ETH10, SPS115, TGLA122, INRA023, BM1818, ETH3 and BM1824. The heifer’s body weight was measured at birth, at weaning, and at the age 8, 12, 15 and 18 months. Individual heterozygosity estimates (for each microsatellite loci separately) and microsatellite multilocus heterozygosity (for all used loci) estimates (MLH) were used in the analysis. ANOVA was used to determine the relationship of the dependent effects (body weight at different ages) to single locus heterozygosity using two classes: 0 (for homozygous individuals) and 1 (for heterozygous individuals). In addition, the following indicators were calculated for each genotype: the squared distances (d2) between the length of both alleles within the individual genotype for each microsatellite loci, as well as the mean squared distance (multilocus d2) between the lengths of both alleles within the individual genotype for ten microsatellite loci. Spearman’s rank correlation coefficients were used to measure the association between d2 scores (for each microsatellite loci) and body weight at different ages. The influence of different grades of estimates of MLH and mean d2 classes was also assessed based on ANOVA. Heterozygosity at locus BM2113 was significantly (P < 0.01) associated with heifer’s body weight at the age of 15 months and heterozygosity at locus BM1818 was significantly (P < 0.05) associated with heifer’s body weight at the age of 8 months. Significant Spearman’s rank correlations (P < 0.01...0.05) were also observed between the body weight and d2 score for four microsatellite loci BM2113, SPS115, ETH3 and BM1824. Individual mean heterozygosity estimates for 10 microsatellite loci and mean d2 estimates were weakly associated with weight performance in Southern meat cattle breed heifers.
Changes in the physicochemical properties of whey and cottage cheese produced from the milk of Ukrainian black-and-white dairy cows with different genotypes of kappa-casein during storage
Authors: Polieva I. О. , Korh I. V.
Published: December 2021

The article presents experimental materials on the study of changes in the whey and cottage cheese physicochemical properties which are made from the milk of Ukrainian black-and-white dairy cows with different kappa-casein genotypes during storage. The experimental part of the work was carried out in the conditions of a pedigree plant for breeding Ukrainian black-and-white dairy breed of the «Profintern» unit of the State Enterprise «Gontarivka» in the Institute of Animal Science of the National Academy of Agrarian Sciences (NAAS). Based on the analysis results of the chemical composition, there were no significant differences between the groups for most indicators during storage in the period from the first to the 15th day, although in absolute values they can be placed in the following order: cottage cheese made from milk of cows with the BB genotype, AB and AA. It was found that the concentration of active acidity, similar to most quality indicators of cottage cheese, was determined at the beginning of storage by a higher value in cows with genotype BB by 0.9 and 0.5% compared to animals with genotypes AA and AB. With the extension of the shelf life, the rate of acid formation tended to decrease and on the 15-th day was 3.8–3.1%, compared the initial values. In contrast, the difference between the samples from the representatives with the BB and AA genotype in terms of the activity of hydrogen ions during this period was 1.6% and the AB genotype – 0.9%. Despite the fact that the duration of storage had a negative effect on the hydrogen ions’ concentration in cottage cheese, made from cow’s milk with different genotypes of kappa-casein, its moisture-retaining properties, on the contrary, have improved. It was found that cottage cheese and whey, regardless of the cows’ genotype at the kappa-casein locus, during storage have a relatively stable composition and meet the requirements of the current DSTU. The recommended shelf life is 15 days. The best combination of the studied parameters in the production of BB genotype cows reflects the higher course of metabolic processes in the body, which led to an improvement in its quality.
Islam and the Other: A Study on the Image of The Other in Early Muslim Societies
Authors: Özel Cemal
Published: December 2021

In this study, the Byzantine image in the religious and literary texts produced by Muslim societies in the first four centuries of the Hijra has been examined in terms of historical process. To this end, first, a theoretical basis has been established within the framework of the concepts of identity, difference, other, and othering. Then, the imagery of Byzantium is analyzed through the interpretation of the first five verses of the Surah Rûm, with regards to naming, politics, religion, culture, science, philosophy, art and women's descriptions. The main argument of the study is that the Byzantine image of Muslims cannot be addressed independent of the relationships established with Byzantium. From a historical point of view, it is seen that the image of Byzantium, which was initially positive, turned into negative depending on the course of relations and was balanced over time in terms of change, while the style and content of political and political imagery varied, there is very little variation in descriptions of social life with regards to Constantinople, Byzantine craftsmanship, family life and women. While the Qur'an and the Sunnah culture formed the basis of the Byzantine perception in the early days, political developments became dominant over time. On the other hand, Muslims did not deal with Byzantium in a monolithic, shallow and reductive way, but they used the distinction between “us” and “them” to improve the image of Islam and reinforce Muslim identity.
Review of The economics of climate change in Argentina
Authors: Scholvin Sören
Published: December 2021

The economics of climate change in Argentina, edited by María Belfiori & Mariano Rabassa. Springer, 2021
A Novel LysR Family Factor STM0859 is Associated with The Responses of Salmonella Typhimurium to Environmental Stress and Biofilm Formation
Authors: MA ZHONGMEI , LI NA , NING CHENGCHENG , LIU YUCHENG , GUO YUN , JI CHUNHUI , ZHU XIAOZHEN , MENG QINGLING , XIA XIANZHU , ZHANG XINGXING , CAI XUEPENG , CAI KUOJUN , JUN QIAO
Published: December 2021

Salmonella enterica subsp. enterica serovar Typhimurium (ST) is an intracellularly parasitic bacterium. This zoonotic pathogen causes food poisoning and thus imposes a severe threat to food safety. Here, to understand the regulatory roles of the novel transcription factor STM0859 on the response of ST to environmental stress and biofilm formation, the STM0859 gene-deficient strain and the complementation strain ΔSTM0859/STM0859 were generated, respectively. Then, its capacity of responding to environmental stresses and biofilm (BF) formation ability under different stresses, including acid, alkali, high salt, cholate, and oxidative stresses was tested. We further analyzed the interaction between the STM0859 protein and the promoter of the acid stress response-related gene rcsB by performing an electrophoresis mobility shift assay (EMSA). The results showed that acid resistance and BF formation capacities of ST-ΔSTM0859 strain were significantly weaker, as compared with those of Salmonella Typhimurium SL1344 (ST-SL1344) wild strain (p < 0.01). Quantitative qRT-PCR analysis showed that the expression levels of acid stress and BF formation-related genes, rcsB and rpoS, of ST-ΔSTM0859 strain were significantly reduced at the transcription levels, while the transcription levels of these genes were fully restored in complementation strain ST-ΔSTM0859/STM0859. The results of EMSA showed that STM0859 was capable of binding the promoter DNA fragments of the rcsB gene, suggesting that STM0859 can promote the transcription of the rcsB gene through interaction with its promoter, thereby exerting an indirectly regulatory role on the adaptive responses to acid stress and BF formation of ST. This study provided new insights into the regulatory mechanisms of the LysR family factors on the tolerances of ST under adverse environmental stresses.
Development of A Soil Resistivity Calculator
Authors: Ezhar Muhd Anas , Siow Chun Lim
Published: December 2021

Soil resistivity is an important parameter for designing electrical earthing system. The measurement of soil resistivity is greatly influenced by moisture content, temperature, porosity, degree of saturation, number of soil layer(s), and frequency of lightning current. Researchers have proposed various methodologies to provide an approximation of soil resistivity using the listed parameters. In order to ease the process of estimating soil resistivity at a particular area, there is a pressing need to devise a simple tool that enables the calculation of soil resistivity in the most accurate manner. As such, this research proposes a reliable tool for quick evaluation of soil resistivity based on various methodologies using Microsoft Excel’s built-in-functions and Visual Basic Application (VBA) Next, the developed tool was validated using two methods, in which the output value of the calculator was compared with data retrieved from IEEE Std 142-2007 and data reported in past studies. The validation results revealed that the developed calculator may serve as a significant application in future due to its time-saving and cost-effective attributes.
Електронні комунікації як важливий елемент сталого функціонування критичної інфраструктури
Authors: Гнатюк Сергій , Скибун Наталія , Живило Євген , Волошко Сергій
Published: December 2021

Вивчення ролі електронної мережі Інтернет допускає величезну різноманітність дослідницьких підходів: вона може розглядатися як інформаційна технологія, як психосоціологічний феномен, як спільнота, як фольклор, як універсальна база даних і т.д. З точки зору комунікативних цілей спілкування за допомогою Інтернету має все те різноманіття, яке притаманне іншим різновидам комунікації, - це видно неозброєним оком при першому ж зверненні до змісту електронних повідомлень. В рамках вказаного дослідження було розглянуто електронні комунікації в контексті важливого елементу сталого та безпечного функціонування критичної інфраструктури в Україні. Було відзначено, що електронні комунікації разом із інформаційною інфраструктурою виступають, в сучасних умовах, основою інформаційно-комунікаційних систем управління об’єктів інформаційної критичної та критичної інфраструктур. Рівень впливу електронних комунікацій на стале та безпечне функціонування об’єктів критичної інфраструктури зростає разом із подальшою цифровізацією комунікацій та процесів, запровадження автоматичних та автоматизованих систем управління, використання елементів штучного інтелекту та Інтернету речей.