bluuebunny/crossref_metadata_2025 huggingface dataset:
Expression levels of the selenium-uptake receptor LRP8, the antioxidant selenoprotein GPX1 and steroidogenic enzymes correlate in granulosa cells
Authors: Hummitzsch Katja , Kelly Jasmine E , Hatzirodos Nicholas , Bonner Wendy M , Tang Feng , Harris Hugh H , Rodgers Raymond J
Published: July 2024

Graphical abstract

Reactive oxygen species (ROS) are a by-product of the activity of cytochrome P450 steroidogenic enzymes. Antioxidant enzymes protect against ROS damage. To identify if any particular antioxidant enzyme is used to protect against ROS produced by granulosa cells as follicles enlarge and produce oestradiol, we measured in the bovine granulosa cells the expression of two steroidogenic enzymes (CYP11A1, CYP19A1), important for progesterone and oestradiol production. We also measured the expression of the members (FDXR, FDX1, POR) of their electron transport chains (ETC). We measured antioxidant enzymes (GPXs 1–8, CAT, SODs 1 and 2, PRDXs 1–6, GSR, TXN, TXNRDs 1–3). Since selenium is an active component of GPXs, the selenium-uptake receptors (LRPs 2 and 8) were measured. Only the selenium-dependent GPX1 showed the same increase in expression as the steroidogenic enzymes did with increasing follicle size. GPX4 and PRDX2/6 decreased with follicle size, whereas SOD1/2, CAT, GSR, and TXNRD3 were lowest at the intermediate sizes. The other antioxidant enzymes were unchanged or expressed at low levels. The expression of the selenium-uptake receptor LRP8 also increased significantly with follicle size. Correlation analysis revealed statistically significant and strongly positive correlations of the steroidogenic enzymes and their ETCs with both GPX1 and LRP8. These results demonstrate a relationship between the expression of genes involved in steroidogenesis and selenium-containing antioxidant defence mechanisms. They suggest that during the late stages of folliculogenesis, granulosa cells are dependent on sufficient expression of GPX1 and the selenium transporter LRP8 to counteract increasing ROS levels caused by the production of steroid hormones.

Lay summary

In the ovary, eggs are housed in follicles which contain the cells that produce oestrogen in the days leading up to ovulation of the egg. Oestrogen is produced by the action of enzymes. However, some of these enzymes also produce by-products called reactive oxygen species (ROS). These are harmful to eggs. Fortunately, cells have protective antioxidant enzymes that can neutralise ROS. This study was interested in which particular antioxidant enzyme(s) might be involved in neutralising the ROS in follicle cells. It was found that only one antioxidant enzyme, GPX1, appeared to be co-regulated with the enzymes that produce oestrogen and progesterone in the follicular cells. GPX1 contains the essential mineral selenium. In summary, this study has identified which antioxidant appears to be involved in neutralising ROS in the days leading to ovulation. It highlights the importance of selenium in the diet.
A MULTIFACETED FRAMEWORK FOR CRITICAL DIGITAL LITERACY IN TRANSFORMING HUMAN RESOURCES
Authors: Fadilah Eka
Published: July 2024

ABSTRACTThis study endeavors to reinvigorate the concept of critical digital literacy within the framework of English language teaching in Indonesia. Employing a desk study methodology, a nexus analysis was conducted, encompassing theoretical frameworks, empirical research, political-ideological considerations, governmental and global institutional policies, and pedagogical possibilities related to the integration of critical digital literacy with digital technology in education. The data analysis involves the systematic deconstruction and synthesis of existing literature frameworks to establish emergent categories. These categories were subsequently thematized into a model, serving as a heuristic framework that spans the multifaceted domains of digital text, digital reader, digital task, and digital values. The framework underscores the imperative to prioritize human transformation and empowerment over a sole focus on digital technology utilization. It emphasizes the collaborative efforts required among stakeholders in English language teaching practices.ABSTRAKPenelitian ini berupaya untuk menyegarkan kembali konsep literasi digital kritis dalam kerangka pengajaran bahasa Inggris di Indonesia. Dengan menerapkan metodologi desk study, analisis nexus diterapkan dengan menggabungkan kerangka teoritis, penelitian empiris, pertimbangan politik-ideologis, kebijakan pemerintah dan lembaga global, serta peluang-peluang pedagogis terkait integrasi literasi digital kritis dengan teknologi digital dalam pendidikan. Analisis data melibatkan dekonstruksi sistematis dan sintesis terkait dengan kerangka literatur yang ada untuk membentuk kategori-kategori yang muncul. Dari kategori-kategori tersebut kemudian di bentuk menjadi tema yang kemudian dikembangkan sebuah model yang berfungsi sebagai kerangka heuristik yang mencakup domain-domain beraneka bentuk, seperti teks digital, pembaca digital, tugas digital, dan nilai-nilai digital. Kerangka ini menekankan pentingnya untuk memberikan prioritas pada transformasi dan pemberdayaan manusia dibandingkan dengan fokus semata-mata pada pemanfaatan teknologi digital. Penekanan diberikan pada upaya kolaboratif yang diperlukan di antara para pemangku kepentingan dalam praktik pengajaran bahasa Inggris.How to Cite: Fadilah, E. (2023). A Multifaceted Framework for Critical Digital literacy in Transforming Human Resources. IJEE (Indonesian Journal of English Education), 10(2), 463-486. doi:10.15408/ijee.v10i2.32036.
Reflection on Students' Competence and Challenges in Achieving Digital Media Literacy in English Learning
Authors: Menggo Sebastianus
Published: July 2024

This study aims to investigate and disclose the students' profiles and the obstacles that stand in the way of obtaining digital media literacy in English instruction for high school students in Ruteng City, Indonesia. This study surveyed 595 students from six Senior High Schools in Ruteng City, Indonesia. The questionnaire served as the primary instrument for data collection, followed by quantitative and qualitative analysis of the findings. The study results indicated that the level of media literacy competence among students falls into the low category (2,84). This category was indicated by eight statements of media digital literacy competence. Moreover, five factors challenged the respondents' digital media literacy achievement, namely lack of students' enthusiasm and initiative in regards to digital media literacy (61,59%), lack of cost for purchasing internet data packages (71,20%), insufficient time allocated for the use of specific English learning software (59,48%), unstable internet network connectivity (58,27%), and lack of available ICT infrastructure in schools (58,33%). Various issues hinder the level at which students might acquire digital media literacy skills, and stakeholders are encouraged to address or overcome these obstacles.
Programmvorstellung – „Gemeinsam Digital! Kreativ mit Medien!“
Authors: Wellingerhof Anne
Published: July 2024

Der Artikel beschreibt die Fördermöglichkeiten und Rahmenbedingungen des dbv-Förderprogramms „Gemeinsam Digital! Kreativ mit Medien“ im Rahmen des bundesweiten Programms „Kultur macht stark“ des Bundesministeriums für Bildung und Forschung (BMBF). Anhand eines konkreten Praxisbeispiels einer öffentlichen Bibliothek mit zwei Kooperationspartnern zeigt es Möglichkeiten der kulturellen Bildung im Bereich Medienbildung und digitaler Leseförderung für Kinder im Kindergartenalter ab drei Jahren auf.
Optical Photoluminescent Properties of Plant Seeds when Infected with Mycopathogens
Authors: Belyakov Mikhail V. , Moskovskiy Maksim N. , Efremenkov Igor Yu. , Novikov Vasiliy S. , Kuznetsov Sergey M. , Boyko Andrey A. , Mikhailichenko Stanislav M.
Published: July 2024

Introduction. Using digital technologies such as optical monitoring of grain quality will reduce losses of grain crops caused by infection with mycopathogens.
Aim of the Study. The study is aimed at investigating spectral characteristics, excitation parameters and luminescence of cereal seeds when infected with mycopathogens to determine informative spectral ranges and subsequent development of infection control methods.
Materials and Methods. In the study, there were used wheat and barley seeds inoculated with Fusarium graminearum, Alternaria alternata. Excitation and luminescence registra- tion spectra were measured by a diffraction spectrofluorimeter CM 2203 in the range of 230–600 nm. Integral and statistical parameters of spectra were calculated with the use of Microcal Origin program.
Results. It was found that the spectral absorbency of seeds decreases when infected with mycopathogens. For wheat, the integral absorption parameters decrease more significantly when infected with alternaria, and for barley, on the contrary, a greater decrease occurs when infected with fusarium. In the area of 230–310 nm, new excitation maxima appear in infected seeds. When excited by radiation with a wavelength of λ = 284 nm, the spectral and integral characteristics and parameters of infected seeds exceed those for uninfected ones. When excited with 424 nm and 485 nm radiation, the number of disease-free seeds of both wheat and barley exceeds the number of infected seeds.
Discussion and Conclusion. The changes in excitation and photoluminescence spectra can be explained by the substitution of polysaccharides and proteins during mycoculture uptake and modification. To objectively monitor the mycopathogen infestation of seeds, it is advisable to use a photoluminescence range of 290–310 nm when excited by radiation of about 284 nm. To determine if the infection caused with fusarium or alternariasis, photoluminescence monitoring should be used in the range of 380–410 nm.
Proposed Revisions to Shear-Friction Provisions
Authors: Shaikh A. Fattah
Published: July 2024

This paper gave us the basis for the effective shear friction coefficient still used in the PCI Handbook.
The gallows in Holíč (Skalica district, Slovakia) archaeological research and virtual reconstruction
Authors: Bešina Daniel , Bönde Gogová Stanislava , Šteiner Pavol
Published: July 2024

The archaeological research of the gallows in Holíč is one of the first purposefully surveyed sites of this kind in Slovakia. The issue of research on execution sites is only marginally dealt with in our territory. The research confirmed the presence of a simple brick gallows with two supporting posts. Skeletal remains of human bodies discovered in the excavated area are no less important in this context. The information and the finds can contribute to the study of capital execution and types of gallows not only in the territory of today's Slovakia, but also in the wider area of the historical Kingdom of Hungary. The features datable to the Second World War are also worth mentioning and provide an ideal opportunity to compare archaeological finds of modern military history with the available written sources.
Rufus Estes: Good Things to Eat As Suggested by Rufus
Authors: Jaine Tom
Published: July 2024

Rufus Estes: Good Things to Eat As Suggested by Rufus: Howling at the Moon Press, Jenks, Oklahoma, 1999: ISBN 0-9654333-1-5:142 pp., b/w photos, p/b, $19.95.
Alamelu Vairavan and Patricia Marquardt: Healthy South Indian Cooking
Authors: Jaine Tom
Published: July 2024

Alamelu Vairavan and Patricia Marquardt: Healthy South Indian Cooking: Hippocrene, 2001: ISBN 0-7818-0867-7: 348 pp., photos, h/b, $24.95.
Cherie Y. Hamilton: Cuisines of Portuguese Encounters
Authors: Jaine Tom
Published: July 2024

Cherie Y. Hamilton: Cuisines of Portuguese Encounters: Hippocrene Books, New York, 2001: ISBN 0-7818-0831-6: 377 pp., b/w illus., h/b, $24.95.
The formation of G.N. Speransky Moscow Children’s Hospital No. 9 as the metropolitan centre for pediatric competencies (to the 100th anniversary of its foundation)
Authors: Shelkova Vera N.
Published: July 2024

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Outstanding pediatrician and founder of the school of pediatric ecopathology, mentor — L.S. Baleva
Authors: Yakusheva Elena N. , Sipyagina Alla E.
Published: July 2024

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Experimental Study of the Regularities of Deformation of the Rubber Cord Shell of a Pneumatic Spring of High-Speed Rolling Stock
Authors: Kuzyshyn A. Ya. , Kovalchuk V. V.
Published: July 2024

Purpose. The aim of this work is to establish the regularities of deformation of the rubber cord shell in the vertical and horizontal directions in the case of changes in the internal pressure in the pneumatic spring by static experimental studies. Methodology. A static test bench was used to establish the regularities of deformation of the rubber cord shell of a pneumatic spring. Changes in the internal pressure in the pneumatic spring were achieved using a compressor, and the deformation of the rubber cord shell was measured directly by high-frequency potentiometric linear displacement sensors. The deformation of the rubber cord shell of a pneumatic spring in both the vertical and horizontal planes was studied under the condition of changing the internal pressure in the spring in the range from 0 to 5 atm. Findings. Using the designed test bench, a methodology for experimental studies of the deformation of a rubber cord shell with increasing internal pressure in a pneumatic spring was developed. The dependences of the deformation value of the rubber cord casing of a pneumatic spring when the internal pressure changes in the range of 0÷5.0 atm were obtained. It is established that the deformation of the rubber cord casing with an increase in the internal pressure in the pneumatic spring in the horizontal plane is more intense compared to the vertical plane. It is found that the maximum values of deformation of the rubber cord shell of a pneumatic spring in the vertical and horizontal directions are observed at the initial stage of air injection in the range of pressure changes from 0 to 0.5 atm. The polynomial equations describing the deformation dependences of the rubber cord shell of a pneumatic spring were obtained. Originality. The regularities of deformation of the rubber cord casing in the vertical and horizontal planes at different values of the internal pressure in the pneumatic spring were determined by experimental static studies. Practical value. The study of the regularities of deformation of the rubber cord shell will contribute to a more accurate modeling of the operation of the pneumatic spring and a reliable determination of its dynamic performance. This will make it possible to use the dynamic performance of the air spring in the spatial mathematical model of the rolling stock at the design stage, as well as to evaluate its dynamic performance and traffic safety indicators.
Increasing the Fuel Efficiency of a Mainline Diesel Locomotive with Separate Section Loading
Authors: Riabov Ye. S. , Yeritsian B. Kh. , Kolodii I. M. , Ivanov S. V. , Sych O. A. , Halych A. V.
Published: July 2024

Purpose. The paper aims to investigate the increase of fuel efficiency of a mainline freight locomotive in the case of separate loading of diesel generators of its individual sections. Methodology. The study was carried out for the non-electrified section between Kharkiv-Sorting and Sumy stations during the movement of a freight train with 45 loaded and empty freight cars in both directions. The movement of a train with a freight mainline two-section diesel locomotive 2TE116 was taken. To determine the parameters of the movement, a mathematical model was developed, which was used to solve a series of traction problems. The traction problems are calculated for the cases of train movement with a series diesel locomotive and a diesel locomotive with separate loading of diesel generators of its individual sections. A method of loading sections is proposed for modeling and the traction characteristics of the locomotive are constructed in accordance with this method. Findings. It has been established that the use of separate loading of diesel generators of individual sections of a diesel locomotive when running a train with loaded cars reduces fuel consumption by 18.7...19.6 % compared to running a serial diesel locomotive. For the case of a train with empty cars, the reduction in fuel consumption is 8.1...10.3 % compared to a train with a serial diesel locomotive. It has been found that the movement of a train with empty cars can be carried out with traction by one section of a diesel locomotive. In this case, the reduction in fuel consumption is 29.5...31.0 %. In all the studied cases, the duration of the movement is practically the same. Originality. The authors of this paper have solved traction problems for a real track section when a train with a freight diesel locomotive is moving, where separate loading of diesel generators of its sections is used. A method for forming the traction characteristics of a locomotive with separate loading of diesel generators is proposed. Practical value. The developed mathematical models of train movement, including for the case of separate loading of diesel generators of diesel locomotive sections, can be used in the modernization of diesel locomotives or the creation of diesel rolling stock using a multi-diesel power plant.
Determination of the Efficiency of Steel Structures of a Warehouse Building Roof
Authors: Misiura Ye. A.
Published: July 2024

Purpose. The main purpose of this article is to compare the main technical and economic indicators of two proposed structural variants of steel coverings for a class B+ warehouse building in the city of Dnipro. The relevance of the work is related to the constant increase in the volume and pace of freight transportation both globally and in Ukraine, especially in recent years. This requires the creation of new and expansion of existing warehouses of various types. In turn, this leads to the need to create such load-bearing structures for storage areas that would be able to cover significant spans and at the same time ensure minimal costs for their construction and operation. Methodology. To achieve this goal, we analyzed modern classifications of warehouse buildings according to national standards and international approaches, determined the class of the building in question according to these two methods, and developed two structural options for steel roofing - based on a load-bearing beam in the form of a truss truss and based on a beam-frame scheme. Finite element models for both proposed structural options were built using the domestic design complex Lira-CAD. Based on the analysis of their stress-strain state, rational cross-sections were selected for each design option, and the total weight and cost were calculated. Findings. A comparative analysis of the two developed structural solutions for the steel roof of a warehouse building revealed that the variant with the use of a beam-frame system has about 10% less weight and cost. Also, its manufacturability is higher than that of the truss system. Originality. As a result of the numerical analysis, a more rational and efficient design solution for the steel roof of a warehouse building in the city of Dnipro was theoretically substantiated. Practical value. A constructive variant of the steel coating has been developed and proposed for practical implementation, which, in terms of its technical and economic indicators, is the most effective for the conditions of a modern industrial enterprise. Also, the developed constructive variant of the warehouse building is classified in accordance with domestic and international modern approaches.
Mathematical Modeling of the Process of Acid Rain Formation in Case of Emissions from Thermal Power Plants
Authors: Biliaiev M. M. , Petrenko V. D. , Biliaieva V. V. , Berlov O. V. , Zvonarova O. V.
Published: July 2024

Purpose. It is known that acid rain has a negative impact on the environment. The formation of acid precipitation in the atmosphere occurs as a result of the chemical interaction of fuel combustion products and atmospheric humidity. Acid rain leads to crop losses, deterioration of soil fertility, and acidification of water in reservoirs. The development of scientifically based methods for studying the intensity of such acidic pollution of the air and soil surface in regions with significant emissions from thermal power plants remains an urgent problem. To solve this problem, it is important to use mathematical modeling, since it is impossible to determine the impact of emissions from thermal power plants on the formation of acid rain experimentally. Therefore, the main goal of the work is to create a mathematical model for predicting the formation of acid rain in the event of emissions from thermal power plants. Methodology. To predict the process of acid rain formation, a three-dimensional equation of convective diffusion transport of a pollutant is used, which takes into account the wind speed profile, atmospheric stratification, emission intensity of an impurity, and wind direction. This equation is also used to describe the process of water vapor transport in atmospheric air. To describe the process of acid formation in atmospheric air, a stoichiometric relationship is used. The numerical integration of the modeling equation of transfer was carried out using the splitting method. Findings. A multifactorial numerical model was built that allows determining the zones where acid rain is formed. The problem of predicting the formation of acid rain in the case of emissions from thermal power plants on the basis of the constructed numerical model is considered. Originality. A numerical model is proposed to predict the occurrence of acid rain due to emissions from thermal power plants. The model is multifactorial and takes into account convection, atmospheric diffusion, and an uneven wind profile. A computer code has been created that allows for rapid assessment of acid pollution zones. Practical value. The developed computer code for analyzing the zones of acidic pollution of the environment in the case of industrial emissions makes it possible to predict the intensity of such pollution in various meteorological conditions.
Echo-loop of subclinical cardiovascular toxicity in women associated with HER2-positive breast cancer therapy
Authors: Pershukov I. V. , Akbalaeva B. A. , Shulzhenko L. V. , Batyraliev T. A. , Gurovich O. V. , Vinogradskaia V. V. , Karben Z. A. , Fettser D. V. , Kuznetsova T. N. , Ivanenkova E. Yu. , Raiimbek uulu N. , Kvasova M. V. , Kalmatov R. K. , Imetova Ja. B. , Mamatova S. M. , Jainakbayev N. T. , Seidalin A. O. , Rakhalskaya N. N.
Published: July 2024

Aim. To assess the incidence and timing of subclinical cardiac dysfunction associated with therapy for HER2-positive locally advanced or metastatic breast cancer, and to analyze the difference in time from significant reduction in left ventricular (LV) global longitudinal strain (GLS) to significant reduction in LV ejection fraction (LVEF) (cardiotoxicity "echo-loop").

Material and methods. A total of 187 women 58±11 years without baseline cardiac dysfunction with verified HER2-positive locally advanced or metastatic breast cancer who received sequential adjuvant therapy with doxorubicin+cyclophosphamide, docetaxel+trastuzumab and trastuzumab monotherapy were followed up in 4 centers in four countries within 12 months with regular (every 3 weeks) speckle-tracking echocardiographic monitoring.

Results. Subclinical cardiac dysfunction associated with breast cancer therapy (CTRCD) appears in each block of therapy after the first course. Its frequency increases significantly after each subsequent course compared to the previous one. By the end of the 4th course in each block of therapy, subclinical CTRCD is noted from 24,6% (almost every 4th patient in the chemotherapy block) to 32,6-33,7% (almost every 3rd patient in the chemotherapy and targeted therapy blocks). In 24 out of 25 cases of severe subclinical CTRCD (96%) with a fall in LVEF <40%, a decrease in LV GLS >15% was preceded. The time difference from a decrease in LV GLS to a decrease in LVEF <40% (cardiotoxicity "echo loop”) ranges from 5 to 16 weeks depending on the cancer therapy option.

Conclusion. Until recently, the period of identified moderate subclini­cal cardiac dysfunction was not used to prescribe therapy for the pre­vention and treatment of cardiotoxicity. Enhanced speckle-tracking echo­cardiographic monitoring may reduce the incidence of severe sub­clinical and overt clinical cardiac dysfunction. Guidelines for car­diotoxicity monitoring should be reviewed to reduce the incidence of se­vere cardiac complications of cancer therapy.
Changes of carbohydrate metabolism and insulin resistance parameters at different compliance levels in young people
Authors: Sineglazova A. V. , Fakhrutdinova A. Sh.
Published: July 2024

Aim. To analyze early disorders of carbohydrate metabolism and insulin resistance (IR) at different compliance levels in young people.

Material and methods. Ninety-four patients (45 men/49 women; median (Me)=33 [28,7-38] years) were examined. This prospective observational study used data of the questionnaire of the quantitative assessment of the adherence to treatment (QAA-25), fasting plas­ma glucose levels, oral glucose tolerance test, levels of glycated hemo­globin (HbA1c), insulin and Homeostasis Model Assessment of Insulin Resistance (HOMA-IR). Statistical processing was carried out in IBM SPSS Statistics 26.

Results. Only 15,8% had high adherence to medical support, 8,9% — lifestyle modification (LM) and general compliance, 10,9% — drug therapy. The means for most types of adherences were in the low range. In the low and medium LM groups, over 18 months the number of patients with elevated HbA1c levels increased from 7,1 to 18,8% (p=0,021) and IR from 12% to 31,8% (p=0,000). In patients with low overall LM compared to high ones, the probability of HbA1c increase raised by 5,5 times, and hyperinsulinemia by 1,16 times.

Conclusion. In an 18-month prospective study, young adults with low compliance levels showed an increase in the incidence of hyper­insulinemia, IR, and prediabetes.
The protective role of postpartum resilience on anxiety rates of Brazilian mothers during the COVID-19 pandemic
Authors: Scholl Carolina Coelho , Coelho Fernanda Teixeira , Rubin Bárbara Borges , Ávila Caroline Nickel , Petry Isabela , Rosa Kathreim Macedo da , Martins Rayssa da Luz , Silva Victória Duquia da , Weizer Mariana , Trettim Jéssica Puchalski , Matos Mariana Bonati de , Pinheiro Ricardo Tavares , Quevedo Luciana de Avila
Published: July 2024

ABSTRACT Objective: We evaluated the protective effect of postpartum resilience (measured before the pandemic onset) on the prevalence of moderate to severe anxiety symptoms during the coronavirus disease (COVID-19) pandemic. Methods: The sample included 589 mothers from a longitudinal study in southern Brazil. Three months after delivery we assessed maternal resilience through the Resilience Scale (RS). The Generalized Anxiety Disorders 7-item (GAD-7) was used to assess anxiety symptoms during the COVID-19 pandemic. Results: The prevalence of severe to moderate anxiety symptoms in this sample was 28.4% (95% CI: 25.0; 32.0). Resilience showed to be a protective factor against moderate to severe anxiety symptoms during the pandemic (OR: 0.98; p<0.001). Conclusions: The results showed that postpartum resilience is a factor associated with lower odds of a more intense manifestation of anxiety during pandemic periods. Thus, strengthening resilience by reinforcing appropriate coping strategies can prevent mental health problems.
Evaluation of the psychometric properties of the Brazilian version of the Short Portable Mental Status Questionnaire (SPMSQ) by Pfeiffer
Authors: Teigão Fernanda Cury Martins , Moser Auristela Duarte de Lima , Fidalski Solena Ziemer Kusma
Published: July 2024

Abstract Objective To evaluate the psychometric properties, including validity, reliability, sensitivity, and specificity of the SPMSQ-BR. Method The analysis was conducted on 93 older adults, assessed with the Brazilian version of the SPMSQ, Mini-Mental State Examination (MMSE), Clock Drawing Test (CDT), and Verbal Fluency Test (VFT). Internal consistency was estimated using Cronbach's alpha coefficient. In order to assess intra-rater stability and inter-rater reproducibility, the intraclass correlation coefficient (ICC) with a 95% confidence interval was employed. For concurrent and convergent validity, Spearman's correlation coefficient was utilized. Accuracy in establishing the cutoff point for the SPMSQ-BR to screen sensitivity and specificity was assessed through ROC curve analysis. Result The SPMSQ-BR demonstrated excellent internal consistency (α=0.803), high intra-rater and inter-rater reliability (ICC=0.977 and ICC=0.973), respectively. In terms of concurrent validity, it showed a strong negative linear correlation with the MMSE (-0.799, p<0.001), while moderate correlations were found with the CDT (-0.584, p<0.01) and VFT (-0.569, p<0.01). The SPMSQ-BR proved capable of discriminating cognitive impairment with a cutoff point of 3 errors, following the original scale. The area under the curve (AUC) considering education level was 0.905 (sensitivity=81.3%, specificity=76.9%), and without considering education level, the AUC was 0.927 (sensitivity=87.5%, specificity=80.8%), indicating good sensitivity and specificity in both cases. Conclusion The study demonstrated that the Brazilian version of the SPMSQ, established as a Brief Cognitive Capacity Scale, proved to be stable, reproducible, valid, and reliable for assessing the cognitive capacity of older adults. Furthermore, it showed sensitivity in identifying cognitive impairment.
Educação popular em saúde: princípios, desafios e perspectivas na reconstrução crítica do país
Authors: Cruz Pedro José Santos Carneiro , Silva José Carlos da , Danielski Kellin , Brito Pedro Nascimento Araujo
Published: July 2024

O texto trata da abordagem teórico-prática da Educação Popular em Saúde (EPS), apresentando reflexões sobre construções possíveis com base nos princípios dessa filosofia. Esse processo de discussão teórica transita pelos processos educativos em saúde; pela capacidade mobilizadora da participação social e promoção de encontros humanos transformadores nos serviços de saúde; e pelas possibilidades para o presente e o futuro do Sistema Único de Saúde (SUS). Tem-se, pois, a importância da participação social nos serviços de saúde, destacando a abordagem comunitária como estratégia para potencializar o trabalho na Atenção Primária à Saúde e dinamizar a promoção e a vigilância em saúde. Desse modo, com os caminhos viabilizados e orientados pela EPS, pode-se contribuir para a construção de práticas mais democráticas e emancipadoras no SUS.
Popular education in health: principles, challenges and perspectives in the critical reconstruction of the country
Authors: Cruz Pedro José Santos Carneiro , Silva José Carlos da , Danielski Kellin , Brito Pedro Nascimento Araujo
Published: July 2024

The text deals with the theoretical-practical approach of Popular Education in Health (PEH), presenting reflections on possible constructions based on the principles of this philosophy. This process of theoretical discussion covers educational processes in health, the mobilizing capacity of social participation and the promotion of transformative human encounters in health services and the possibilities for the present and future of the Brazilian National Health System (SUS). This highlights the importance of social participation in health services, highlighting the community approach as a strategy to enhance work in Primary Health Care and boost health promotion and surveillance. In this way, the paths made possible and guided by the EPS can contribute to the construction of more democratic and emancipatory practices in the SUS.
Spatial interface of hot-summer and warm-winter regions based on climate adaptation
Authors: Ni Yang , Yuan Wei , Fang Zhou , Zhang Xiaoyang
Published: July 2024

Premised on the intrinsic relationship between climate, architecture and space, this study conducts a comprehensive review of existing research on the interface of architectural space between climate adaptation. In this paper, the principle and mechanism of the ‘climate adaptation–space interface’ are established by examining typical building cases in regions characterised by hot summers and warm winters while factoring in the limitations of previous studies. Finally, employing computational fluid dynamics simulation technology as the primary research method, this study innovatively proposes three key combination modes for the climate adaptation–space interface. Moreover, it obtains design strategies that can optimise ventilation, shading and lighting effects simultaneously within these three modes. These design strategies include the following: (a) ‘component–concave–convex’ – integrating a single-layer horizontal component with concave–convex window openings; (b) ‘window–cavity’ – combining windows with a permeability of 60% and cavities; and (c) ‘components–windows’ – incorporating folding components with windows.
Blockchain-based change management in engineering, procurement and construction projects
Authors: Cao Xinying , Xia Xingmei , Wang Mingzhu
Published: July 2024

Change management is an essential component of an engineering–procurement–construction (EPC) project, which is the process of gathering data on change orders, examining the information in change reports, revising related drawings and updating cost data resulting from changes. Nevertheless, the current information system for change management is primarily centralised, relying on external parties, opaque in its information, lacking trustworthiness and prone to data loss. To overcome these challenges, this paper proposes a blockchain-based information-management system for managing change information in EPC general contracting projects. A blockchain is used to automate the review processes for changes, ensuring transparency, decentralisation and resistance to tampering. This proposed framework addresses the security, transparency, tamper resistance and reliability shortcomings of conventional methods by harnessing the inherent advantages of blockchains, smart contracts, decentralised InterPlanetary File System storage and building information modelling integration. Subsequently, by utilising the Hyperledger Fabric platform, an information-management system was developed to store and manage data about modifications. The proposed system was validated using actual change data from EPC general contracting projects, which demonstrated the efficacy of blockchain technology in ensuring the security and authenticity of change data. This advancement enhances the security of change data and augments the efficiency of change-management practices in EPC projects.
An assessment of run of river hydropower potential in Great Britain
Authors: Golgojan Ana-Diana , White Christopher J. , Bertram Douglas
Published: July 2024

In the UK, hydropower produces 1.65 GW of energy, only 2% of the national capacity. With most large-scale storage-based hydropower potential sites already utilised in the UK, further development is minimal due to financial, environmental and construction time concerns. However, run of river (RoR) is a type of hydropower that has the potential for further development. While there are studies that estimate different ranges of RoR hydropower potential, the last UK-wide study was undertaken in 1989, meaning it is outdated. In this study, a methodological framework was created to assess the potential of RoR hydropower in Great Britain (GB) (Northern Ireland was omitted from this study due to a lack of river flow data). The hydrological, technical, financial and realisable potentials for pico, micro, mini and small RoR hydropower were determined. The results show that the total hydrological potential is 20 GW, the technical potential is 11 GW, the financially viable potential is 320–420 MW and the realisable potential is 290–320 MW. Most realisable schemes are either mini or small, situated in the west and north-west parts of GB. This study adds to the understanding of the RoR potential in GB and offers a reliable estimate of RoR hydropower that can be produced alongside suitable RoR scheme locations.
ÉMILE DURKHEIM’IN POLEMİK REPERTUARI: TOPLUMSALLIĞIN NELİĞİ VE AHLAKIN KÖKENİ SORUNU
Authors: Öztürk Emre
Published: July 2024

Émile Durkheim, bilim olarak sosyoloji ülküsünün en önemli mimarlarından birisidir. O, sosyolojide “olguların dili”yle konuşmayı ilkeleştiren önemli figürler arasındadır. Ancak tüm bu “nesnel”, “olgusal” ve “ilmi” görüntüsüne rağmen, Durkheim aynı zamanda iyi bir polemikçidir. Durkheim’ın metinlerinde sadece olgusal gözlemlere ilişkin genellemeler yer almaz. Durkheim, aynı zamanda agresif, tartışmacı, nüktedan ve eleştirel kimliğiyle öne çıkan iyi bir yorumcu ve “metin yazarı”dır. Özellikle toplumsallık, ahlak, anomi ve sosyalizm gibi konularda Durkheim’ın bu yönü daha baskın bir biçimde tespit edilebilmektedir. Bu makalede Durkheim’ın polemik repertuarı, toplumsallık ve ahlak konusu üzerinden yansıtılmaktadır. Her iki tema, Durkheim’ın sosyoloji projesinin en belirleyici direkleri olduğundan, Durkheim’ın polemik repertuarında geniş bir yer tutar. Durkheim’ın toplumsallığın neliğini ve ahlakın kökenini delillendirme girişiminde bir olgusal tanıtlama yüzeyi bir de polemik mütalaa düzeyi bulunur. Bu anlamda makalenin amacı, Durkheim’ın en belirleyici çalışma odaklarından biri olan toplumsallık ve ahlâk konularında, eksik kaldığı, güçlükle savaştığı, düşünce ikliminin aksaklıklarını sergilediği, satır aralarında gizlenen polemikçi tavrı gündeme getirmektir. Bu yönüyle makale, Durkheim’ı farklı biçimlerde yeniden tartışmaya açmak ve onun polemik yönlerini farklı veçheleriyle daha anlaşılır kılma gayesindedir.
An Effect of Storytelling on Attitude Changes in Deliberative Mini-Publics
Authors: Nakazawa Takashi , Tatsumi Tomoyuki , Souma Yume , Ohnuma Susumu
Published: July 2024

This study aims to explore the relationship between opinion changes and the quality of deliberation in deliberative polls, focusing on the impact of storytelling. Deliberative mini-publics have gained considerable attention as a form of deliberative democracy. While deliberative democracy emphasises the importance of changing participants’ preferences through rational discourse, the existence of a link between opinion changes and deliberation quality has not been thoroughly examined. Furthermore, the influence of alternative forms of communication, such as storytelling, on attitude changes has not yet been investigated. Using data from a deliberation event modelled after a deliberative poll, we conducted a multiple regression analysis to examine the factors that contribute to individual attitude changes, using ‘Opinions,’ ‘Reasons,’ and ‘Personal experience’ as explanatory variables, coded and scored by an index according to the Discourse Quality Index. Our findings revealed that personal experience significantly affected individual opinion changes, although the effect and its direction were inconsistent and contradictory, depending on specific aspects of attitudes. While prior studies have focused on the exchange of reasoned opinions to examine the relationship between opinion changes and deliberation quality, our research suggests that personal storytelling may have an impact on preference changes.
Paul Tillich and the Genesis of Existential Psychology
Authors: Walter M. Fontanini
Published: July 2024

This study traces back the intellectual journey of Paul Tillich while focusing on his central role in the emergence of existential psychology. It starts with a historical overview of Tillich's German roots and discusses his interactions with key figures such as Manheim, Horkheimer, Adorno, and Heidegger, and his move to the US, where he influenced Rollo May and the development of existentialist psychology. The core of the present study explores Tillich's work “The Courage to Be” and juxtaposes it with May's works “The Meaning of Anxiety” and “The Courage to Create”, suggesting a collective reading. This part also highlights Tillich's influence on figures such as Martin Luther King Jr. The conclusion outlines possible avenues of research in existential psychology, gerontology, and the interplay between theology and psychology.
Bürökgyökér, pókháló és maszlag... Népi gyógyászati praktikák a 18–19. századból
Authors: Bálint Petra
Published: July 2024

Ha betegségről vagy gyógyításról esik szó, napjainkban is rendre felemlegetjük a „régiek” tanácsait, praktikáit, az ősi bölcsességet és egyszerűséget, amellyel kezelték egészségügyi problémáikat. Hiszen a betegségek, járványok, balesetek, sérülések nem kímélték felmenőinket, sőt az előző századok emberét sem, ezek megoldására viszont sokkal kevesebb eszközük volt, mint jelen korunkban. Azonban alapvető volt a természethez való fordulás, az élővilág adta növények vagy az állati (sőt emberi) eredetű anyagok használata. Mindezek mellett azonban számolhatunk a néphit körébe tartozó olyan elképzelésekkel is, amelyektől a kor embere szintén javulást és gyógyulást remélt: varázsló eljárások, imák, ráolvasások vagy mágikus gesztusok formájában. Ezek a tényezők – a tapasztalaton alapuló gyógyító eljárások és a néphit elemei – azonban sokszor nem is választhatók el teljesen egymástól.
Формы и методы финансового контроля в системе мер профилактики коррупционных нарушений
Authors: Kozlov N. A.
Published: July 2024

Рассматривается вопрос о месте отдельных институтов финансового права в системе мер профилактики коррупционных нарушений. В последнее время обозначилась явная тенденция возрастания роли финансового права в регулировании общественных отношений. Отношения, складывающиеся в сфере профилактики коррупционных нарушений, не стали исключением. В исследовании показано, насколько значительную роль в данной области играют формы и методы финансового контроля.
Зарубежный опыт применения искусственного интеллекта в судебной системе
Authors: Galkina N. M. , Kuznetsova D. V. , Vorobyev M. A.
Published: July 2024

В последнее десятилетие технологии искусственного интеллекта (ИИ) получают все большее распространение. Положительные эффекты их применения трудно недооценить – оптимизация рабочих процессов, повышение эффективности труда, экономия времени и простота использования. Сегодня мы можем наблюдать, как все большее количество программ на базе ИИ берется на вооружение судебными системами различных стран мира. В России применение ИИ в судебной системе находится на начальном этапе. В связи с этим авторы статьи провели обзор зарубежного опыта применения ИИ в судебной системе и пришли к выводу, что технологии ИИ имеют значительный потенциал в качестве инструмента в системе правосудия, однако при внедрении технологий на базе ИИ необходимо учитывать ряд этических моментов и правовых рисков.
Правовой статус домашних животных: новый взгляд судебной практики на старую проблему
Authors: Bibikov S.E.
Published: July 2024

Освещается проблема защиты нематериальных благ человека и гражданина в связи с утратой домашнего животного, приведен обзор российской судебной практики по спорам о компенсации нравственных страданий. Акцентируется внимание читателя на новом подходе Верховного Суда РФ к разрешению споров о компенсации морального вреда, отмечаются тенденции развития судебной практики по данной категории дел. По результатам исследования данной проблематики приводятся рекомендации по совершенствованию российского правоприменения, предлагаются пути решения ключевых вопросов, имеющих значение для граждан по спорам о возмещении морального вреда. Особое внимание уделяется расчету компенсации морального вреда за гибель домашнего животного.
Налоговое обязательство: признаки и понятие
Authors: Krasyukov A.V.
Published: July 2024

Изучается налоговое обязательственное правоотношение, выделяются его важнейшие признаки. Рассматриваются признаки обязательства как межотраслевой категории и обосновывается соответствие налогового обязательства данным признакам. Далее изучаются имеющиеся в науке финансового права подходы к выделению специфических признаков налогового обязательства. На основе изученного материала формулируется подход автора к выделению специфических особенностей налогового обязательства. На основе выделенных признаков дается определение налогового обязательства, опосредующего отношения по уплате налоговых платежей.
Замораживание, наложение ареста и конфискация криптовалют и других цифровых активов: пути решения правовых и процессуальных проблем
Authors: Rastoropov S.V. , Pushkarev V.V.
Published: July 2024

Проводится сравнительно-правовой анализ актуальной правоприменительной практики в отношении криптовалюты и цифровых активов. Для реализации обоснованных интересов органов государственной власти в этой сфере и создания четкого и надежного регулирования авторы предлагают нормативные новации, направленные на предотвращение злоупотребления потенциалом этих активов и изыскание дополнительных полномочий соответствующих государственных органов для их конфискации более быстрым и легким способом.
Преемственность государственности: сущность явления в историко-правовом ракурсе
Authors: Tonkov E.E. , Abdullaev M.N.
Published: July 2024

Рассматривается сущность преемственности государственности как историко-правового феномена на примере развития социально-юридических систем в Дагестане. На основе осмысления результатов теоретико-методологического анализа и фактических данных, характеризующих потенциальную возможность сохранения социумами имманентного своеобразия в эволюционном процессе, дается оценка преемственности как закономерности развития государственности. Являясь органическим принципом развития, преемственность представляется фактором детерминации историко-правовой сущности государственности и содержит комплекс политических, правовых, религиозных и других общезначимых ценностей конкретного периода формирования определенной социосистемы.
Heavy Metal Contamination in Soil and Health Risk Assessment through Onion Consumption in Mojo and Koka, Ethiopia
Authors: Hailu Reta , Nibret Mekonen , Bayissa Leta
Published: July 2024

The objective of this study was to determine the concentration of heavy metals in the soil and horticultural crops grown under irrigation in the Mojo and Koka sites in Oromia, Ethiopia, and to evaluate the potential health risks that these metals may cause to consumers. For this investigation, a total of 50 onion (Allium porrum L.) and 50 soil samples were gathered. The content of heavy metals was measured using Inductively Coupled Plasma Optical Emission Spectroscopy (ICP-OES) after the samples were digested using microwave-assisted digestion. The mean concentrations of examined trace elements in onion (mg/kg) were found in the range of 0.80 to 0.95, for As 1.77 to 0.91 for Sn, 2.09 to 1.49 for Pb, 12.29 to 7.31 for B, 13.85 to 12.33 for Zn, 0.34 to 0.25 for Cd, 1.83 to 1.78 for Hg, 11.29 to 7.54 for Cu, 0.83 to 0.78 for Ni, 0.34 to 0.31 for Co, 78.39 to 42.19 for Fe, 17.03 to 11.56 for Mn, and 1.03to 1.02 for Cr. Given that the average levels of Pb, Hg, Cd, and As in onions at both irrigation sites surpassed the upper limit of allowable levels established by the joint FAO/WHO commission. These metals’ concentrations in soil are found to be within acceptable bounds. As compared to other literatures, their concentration exceeded in both irrigation sites. According to the metal pollution load index, the overall pollution load of trace metals, including As, Pb, Cd, and Hg, was found to be moderately higher in both irrigation locations for the majority of the onions under study. The results, which were computed using an adult consumer’s food intake, indicated that the Pb and Hg dietary exposure levels were much higher than the daily intake amounts that were considered tentatively tolerated. The soil-to-onion transfer factor showed that whereas Fe has a strong sorption to the soil colloids, metal Cu is comparatively poorly maintained in the soil. The degree of metal enrichment in soils and sediments is higher than in other literature, according to the soil pollution indices. Thus, swift action is needed to stop the issue and guarantee public safety along the food system’s supply chain.