bluuebunny/crossref_metadata_2025 huggingface dataset:
Mapping the Research Landscape of 360-degree Visual Integrated Virtual Guides: A Bibliometric Review
Authors: Lingga Purwodani Dio , Alfa Rabyn Aswin
Published: November 2024

Integrating 360-degree images into a building's virtual guide or receptionist is an emerging multidisciplinary study area that needs more focus. The first bibliometric analysis of recent research on the connection between virtual guides/receptionists and 360-degree visuals is presented in this paper. Scopus examined publications from 2019 to 2024 to determine subjects, productivity, impact, and collaboration. The findings indicate a rise in yearly production, with over 62 publications released in 2023 attesting to heightened research activity. Additionally, more recent papers have a larger citation effect, demonstrating their relevance today. Most prolific writers are from the US, the UK, and China. However, developing nations like Indonesia, Denmark, and Iran are among the top authoring nations, suggesting an increasing internationalisation. The West is the focal point of international cooperation. However, alliances with China are growing. This quantitative intelligence is a standard for upcoming research in this enormously promising field. Monitoring by bibliographers ought to go on as the conversation develops. The field of dental health, which is extensively utilised in the dental surgery process, surprisingly dominates the production of studies on this issue; this does not preclude the possibility of using 360-degree visual integration in diverse sectors. More involvement from marginalised stakeholders is required to responsibly develop 360-degree visual integration in virtual receptionists and guides.
Prototipe Kurikulum PBI dan IKMBKM Sesuai Permendikbudristek No.53 Tahun 2023
Authors: Sirait Jumaria , Tambunan Marlina Agkris , Sianturi Canni Loren , Siahaan Mungkap Mangapul , Purba Johannes Riscy
Published: November 2024

This research is based on the paradigm of curriculum application or implementation, so the research data analysis technique uses the ADDIE method, namely Analyze, Design, Development, Implementation, and Evaluation to answer the research problem questions: (a) How is the current prototype of the PBI study program curriculum?; (b) How is the prototype of the PBI study program curriculum according to Permendikbudristek No. 53 of 2023? Thus, the purpose of the study is to determine the current PBI curriculum prototype and the PBI curriculum prototype according to Permendikbudristek No. 53 of 2023. The research was carried out in the odd semester of the 2023/2024 academic year. The research results obtained were in the form of a prototype of the PBI study program curriculum development FKIP-UHKBPNP according to Permendikbudristek RI No. 53 of 2023. Furthermore, the agile development method and prototype of the results of the curriculum development were used to be implemented in the PBI study program FKIP-UHKBPNP. The definition of development in this study is a scientific way to obtain data based on initial data, so that it can be used to produce, develop, and validate products. Product validation is also confirmed to users which is carried out through FGD, zoom, or direct meetings. The state of the arts of the research is a documentation study of the current PBI curriculum prototype and curriculum development to produce a PBI curriculum prototype according to Permendikbudristek RI No. 53 of 2023. Thus, the novelty or newness as a research finding is the PBI curriculum prototype according to Permendikbudristek RI No. 53 of 2023 which will be implemented in the PBI study program FKIP-UHKBPNP.
Dinamika Interaksi Kelas dalam Flipped Classroom: Studi Kasus pada Mata Kuliah Strategi Belajar Mengajar SD
Authors: Sianturi Canni Loren , Tambunan Janwar , Tamba Vivi Alexia
Published: November 2024

This study examines in depth the dynamics of classroom interactions in the Flipped Classroom learning model in the Elementary School Teaching and Learning Strategy course at the Elementary School Teacher Education Study Program, HKBP Nommensen University, Pematangsiantar during the even semester of the 2023/2024 academic year. With a qualitative approach and case study design, data were collected through observation, interviews, and documentation studies. The results showed that providing pre-class materials significantly improved students' readiness and understanding before class discussions. Class discussions became more in-depth and interactive thanks to this preparation, while the use of learning videos made it easier to understand complex concepts. Formative assessments provided immediate and useful feedback for students to improve their weaknesses, while focusing on metacognitive skills such as reflection and planning helped in the development of more effective learning strategies. Flipped Classroom has also been shown to improve students' time management and productivity, as well as enrich social interactions in the classroom through active involvement in both in-class and out-of-class discussions. This model is flexible in assignments, which significantly increases student motivation and engagement. In conclusion, Flipped Classroom not only improves academic understanding but also plays an important role in developing students' social and metacognitive skills, making it an effective learning model in the era of the industrial revolution 4.0.
Peran Micro Teaching dalam Peningkatan Kompetensi Calon Guru Ekonomi
Authors: Shalikha Putri Ayu Anisatus
Published: November 2024

This study investigates how the role of micro teaching courses provides valuable experience to prospective economics teacher students and reveals how students' efforts to improve their competencies as provisions for becoming teachers through micro teaching courses. This study was conducted at Universitas PGRI Wiranegara, Faculty of Pedagogy and Psychology, Economics Education Study Program, specifically on students of the 2021 intake who are currently taking semester 6. This study adopted a case study approach, using semi-structured interviews, Focus Group Discussions (FGDs), and observations for data collection. The findings show that all students of the 2021 intake who were the subjects of this study stated that they practiced at least four skills in micro teaching lecture activities. The first skill is the ability to manage learning, the ability to carry out responsibilities as prospective teachers according to the professional code of ethics and oriented towards students, the ability to communicate and interact effectively and efficiently, and no less importantly, the ability to master economics subject matter comprehensively. This study concludes that prospective economics teacher students can hone and combine pedagogical, personality, social, and professional competencies through micro teaching courses. Given the limitations regarding the generalizability of this research, it is recommended that future research collect more comprehensive data in relation to the depth of reflection and feedback in the education of prospective economics teachers through Introduction to School Environment courses or teaching assistantships in schools.
Paradigma Baru Pembelajaran PKn di Sekolah Dasar dalam Membentuk Karakter Siswa di Era Revolusi Industri 4.0
Authors: Armianti Riska , Bungana Reh , Setiawan Deny
Published: November 2024

The new paradigm in Civic Education (PKn) learning in elementary schools is very important in shaping students' character in the digital era. This study aims to evaluate how innovative approaches and methods in PKn learning can create students who have integrity, ethics, and adequate digital skills. Through literature studies and empirical data analysis from several elementary schools in Indonesia, it was found that technology integration in PKn learning can increase student interest and engagement. Project-based learning, the use of interactive digital media, and internet-based educational applications are important tools in this process. Approaches that emphasize collaboration, critical discussion, and self-reflection have also proven effective in instilling citizenship values ??and digital ethics. The results of this study indicate that by adopting a new paradigm that is adaptive to technological developments, PKn learning in elementary schools is not only able to shape good student character, but also prepare them to become smart and responsible citizens in the digital era. These findings provide important implications for curriculum development and educational practices in elementary schools, especially in facing the challenges and opportunities presented by the digital era.
Analisis Implementasi Metode Role Playing dalam Pembelajaran Kosa Kata Bahasa Jawa Kelas 2 SD Negeri 2 Tahunan
Authors: Rahmi Vadia , Mufid Mufid
Published: November 2024

Javanese language learning in elementary schools plays an important role in preserving regional culture and language. However, challenges in teaching Javanese vocabulary often arise, especially due to the dominance of Indonesian and foreign languages ??in everyday life. In SD Negeri 02 Tahunan, interactive learning methods are needed to increase students' interest in learning Javanese vocabulary. This study aims to analyze the implementation of the Role playing method in learning Javanese vocabulary in grade 2 of SD Negeri 02 Tahunan. The main objective is to identify obstacles and find solutions to improve the understanding of Javanese vocabulary for grade 2 students. This study uses a qualitative approach with a case study design. Data were collected through observation, interviews, and questionnaires from 25 grade 2 students. The implementation process of the Role playing method includes scenario preparation, drama implementation, and learning evaluation. The results showed that the majority of students gave a positive response to the Role playing method. The questionnaire data showed an average score of 948 out of a total of 1,250, with the highest score reaching 120. Students felt it was easier to understand vocabulary and were more confident in using Javanese after participating in Role playing activities. The role playing method has proven to be effective in improving students' understanding of Javanese vocabulary and active participation.
Implementasi Manajemen Berbasis Sekolah (MBS) pada Sekolah Menengah Atas (SMA) Negeri 3 Kepulauan Aru
Authors: Sedubun Popy Diana , Ratumanan Tanwey Gerson , Laurens Theresia
Published: November 2024

This study examines the implementation of School-Based Management (SBM) at SMA Negeri 3 Kepulauan Aru with the aim of evaluating the planning, implementation, and development of educational activities at the school. The method used is a descriptive qualitative approach through interviews with the principal, teachers, and school committee as well as a review of documents related to school planning, curriculum, and learning activities. The results of the study indicate that educational activity planning is carried out through the preparation of the School Development Plan (RPS) and involves various related parties. The curriculum implemented includes the 2013 Curriculum and the Merdeka Curriculum, adjusted to the school's vision and mission. However, several obstacles were still found in the implementation, including limited teaching staff and lack of attention to extracurricular activities. Supervision by the principal is carried out routinely to ensure the quality of learning and improve teacher professionalism. Overall, SMA Negeri 3 Kepulauan Aru has implemented SBM, but there is room for improvement in terms of community involvement and optimization of learning activities.
Analisis Manajemen Program Relawan Pengajar Sinode GPM Pada Sekolah Dasar YPPK Kapahewa Dr. JB Sitanala Klasis Seram Utara Barat
Authors: Solissa Risma Jaftien , Wenno Izaak H , Papaliya Josef
Published: November 2024

This study aims to analyze the management of the GPM Synod Volunteer Teaching Program at SD YPPK Kapahewa from the aspects of planning, organizing, implementing, supervising, as well as supporting and inhibiting factors that affect program control. The method used is qualitative with interview, observation, and documentation techniques. The subjects of the study included volunteers, principals, teachers, volunteer mentors, and students. The results of the study indicate that: i) the planning program includes a structured volunteer recruitment, provisioning, distribution process; ii) the organization of the program runs effectively with a clear structure and good communication between volunteers, teachers, and principals; iii) the implementation of the program challenges discipline, but collaboration between volunteers and the school continues to run well; iv) program supervision is carried out through periodic monitoring and evaluation by the GPM Synod; v) supporting factors include financial support and volunteer motivation, while inhibiting factors are low school discipline and interest in volunteer registration. This study provides suggestions for improving the quality of the management program, including strengthening volunteer training and closer collaboration with the local community.
Estratégias de ensino para desenvolver habilidades de escrita no ensino fundamental I
Authors: Laureto Maria Flávia , Maio Taveira Grande Érica
Published: November 2024

O presente artigo é resultado de um Trabalho de Conclusão de Curso cuja temática recai sobre a prática docente a partir de uma proposta de sequência didática de produção de textos escritos, no sentido de desenvolver nos alunos habilidades necessárias para que possam planejar, escrever e revisar textos de forma autônoma e adequada à faixa de ensino que se encontram. O objetivo teórico do estudo foi o de analisar conceitos através de um levantamento bibliográfico das áreas da Psicolinguística e da Linguística Textual, tendo como base a pesquisa de autores como Vygotsky (2007), Dolz, Noverraz e Schneuwly (2004), Koch (2003), Jesus (1995), entre outros. Como objetivo prático, esta pesquisa buscou apresentar uma sequência didática que evidenciasse a importância do professor enquanto mediador para o desenvolvimento das etapas de planejamento, produção e revisão textual, bem como orientasse, através de atividades práticas e perguntas norteadoras, os melhores caminhos para desenvolver nos alunos as habilidades de escrita, a fim de torná-los cidadãos autônomos, críticos e atuantes nos variados campos da vida social. Como resultado, esta pesquisa concluiu que o professor é o responsável por mediar todo o processo de produção de textos escritos, elaborando estratégias e criando ações didáticas. Além disso, como contribuição prática houve a elaboração de uma sequência didática como sugestão para que os docentes tenham mais uma ferramenta metodológica.
Managing Digitalisation of Secondary Education for Sustainable Development in Imo State, Nigeria
Authors: Mba Callistus Okechukwu , Adieme Franca Ginikachi
Published: November 2024

This study examined how digitalisation of secondary education can be managed for sustainable development in Imo State, Nigeria. Two research questions and two hypotheses guided the study. A descriptive research design was adopted. The population comprised all the 296 principals in the 296 public senior secondary schools in Rivers State. Out of these principals, 170 are males while 126 are females. A sample of 133 principals (77 males and 56 females), representing 45% of the population was drawn using both the simple random sampling and proportionate stratified random sampling techniques. This was determined by the Taro Yamane Formula which gave a minimum sample of 109 principals. The instrument that was used for data collection was a researcher-based 16-item questionnaire entitled: “Managing Digitalisation of Secondary Education for Sustainable Development Questionnaire (MDSESDQ).” It was structured after the four-point Likert rating scale and duly validated by five experts. The internal consistency of the instrument was determined using Cronbach’s Alpha. Reliability coefficients of 0.83 and 0.86 were obtained for the various sections of the instrument respectively, which showed that the instrument was reliable. Mean and standard deviation were used to answer the research questions while z-test was used in testing the null hypotheses at 0.05 level of significance. The findings of the study revealed, among others, that digitalisation of secondary education, which brings about change in learners’ behaviour that will drive sustainable development depends largely on the ways principals manage the available digital learning facilities and harness the teachers towards integrating technological devices in the teaching-learning process. Based on the findings, it was recommended, among others, that the Imo State Ministry of Education should formulate policies that will guide digitalisation process, and also ensure that all the public secondary schools are equipped with digital learning facilities.
Navigating the Green Frontier: The Impact of Digitalization on Environmental Pollution in Selected South East Asian Economies
Authors: Mohd Sidek Noor Zahirah , Hasanah Alfiah , Othman Muhammad Hanif
Published: November 2024

The objective of this paper is to re-examine the impact of digitalization on environmental pollution. Past studies use CO2 as a representation of potential environmental harm. In this paper, environmental pollution is extended to cover other sources of pollution such as methane and nitrous oxide. Prior to the analysis, the cross-dependency and panel unit root tests were conducted to understand the underlying structure of the data and to examine the suitability of the econometrics method used. Given the absence of cross-dependency and the presence of unit roots, the panel ARDL estimation method is used to examine the interplay between digitalization and environmental pollution. In addition, CO2 is segregated into different categories of emission such as CO2 resulting from the production of electricity and heat, manufacturing, and emissions from transportation. The sample consists of ten Southeast Asian countries spanning from 2003 to 2022. Results indicate that digitalization amplifies environmental pollution irrespective of the proxy used. The surge in the number of internet users induces higher emissions due to increased production of electricity and heat, emissions from solid and liquid fuel usage, and transport. Similarly, an increase in mobile users increases CO2 emissions from fuel and liquid consumption, manufacturing, construction, and transportation. Moving forward, it is crucial to consider the adoption of green technology in production and explore alternative energy sources to curtail environmental pollution.
Social-Economic Factors and Christian Marital Stability in Tharaka- Nithi County, Kenya
Authors: Kathenya Dr. Luke Murithi
Published: November 2024

Social-economic status plays significant role by guiding couples pursue and maintain intimacy and healthy marital affairs. It also provides couples with the necessary social and economic elements that improve their social and economic life. The study examined the influence of social-economic factors on Christian marital stability in Tharaka- Nithi County Kenya. Tharaka-Nithi County was purposively selected using purposive sampling technique since it is highly affected by cases of Christian marital divorces and conflicts. It adopted descriptive survey design. The researcher used Krejcie and Morgan sample determination table to determine 254 respondents from 750 target population. 250 married couples were randomly selected using simple random sampling technique and 4 priests purposively sampled using purposive sampling technique. A reliability coefficient of 0.740 was obtained using person’s product correlation coefficient. The researcher made questionnaires were utilized to collect data from 250 married couples and 4 priests. The data was organized and analyzed using inferential statistic of data analysis. Mean and standard deviation was used to analyse qualitative data. T-test was used to test null hypothesis at 0.05 level of significance. The finding of the study revealed that there was significant influence of couple’s income level in Christian marital stability in Tharaka- Nithi County. The study further found that there was a significant influence of couple’s educational level on Christian marital stability in Tharaka- Nithi County. The researcher concluded that Couples’ income level has significant influence on Christian marital stability in Tharaka-Nithi County. Couples’ educational level has significant influence on Christian marital stability in Tharaka- Nithi County. Social-economic factors are fundamental necessities in development and stability of Christian marriages in Tharaka-Nithi County. The researcher recommended that each partner in a Christian marriage should improve income by venturing into business activities. Every partner in marriage should promote educational level by attending technical and vocational educational training institutes.
Why Schools Lack Laboratory and Equipment in Science? Through the Lense of Research Studies
Authors: Mangarin Rey Avila , Macayana Liezl B.
Published: November 2024

This paper examined the root causes of the lack of laboratory and equipment in Science among schools in the Philippines through review of related studies. Findings show that root causes why public schools in the Philippines lack laboratory and equipment in science are budgetary constraints and underfunding, mismanagement and utilization of funds,
The Consequences of Over-Indebtedness and its Effect on Individual Well-Being
Authors: Idris, Nur Hafidzah , Muhammad Nur Syuhada , Taib Norraeffa , Mohd Rafien Nor Shahrina , Mohd Noor Nor Hamiza
Published: November 2024

This study examines the methods used by over-indebted borrowers dealing with the issue of over-indebtedness and its effect on borrowers’ well-being. We identified three broad coping strategies that connected with their well-being: sacrifices for basic needs, economic sacrifice, and social and psychological sacrifice. By utilizing the online data collection technique, we identified that most over-indebted borrowers had to do extra work, deplete savings, and sell or pawn their assets to cope with the over-debt situation. Furthermore, the results also reveal that over-indebted borrowers are experiencing psychological distress in their marriages. Despite the difficulties faced by the over-indebted borrowers, they are not compromising on their children’s education, where the majority disagree with reducing education expenses for their children. The findings of this study opened a new dimension in understanding the impacts on borrowers and may contribute to helping policymakers formulate strategies and support systems to alleviate financial distress among borrowers, which could promote economic stability.
Analysis of collaborative navigation modes in swarm application of UAVs in precision farming systems
Authors:   Krasnoyarsk State Agrarian University, Krasnoyarsk, Russia, Kovalev D.I. ,   National Research University "Tashkent Institute of Irrigation and Agricultural Mechanization Engineers", Tashkent, Uzbekistan, Tueva E.V. , Kuzmik S.R.
Published: November 2024

The article presents an analysis of collaborative navigation modes in the swarm application of UAVs in precision farming systems, taking into account the features of existing UAV swarm management methods. Collaborative use of agricultural UAVs is effective for precision farming systems, and has been developed at various stages of agro-technological operations for precise application of fertilizers and pesticides during field processing. Such application contributes to both high efficiency of precision farming systems and environmental sustainability and safety. For the swarm application of UAVs, communication-based collaborative navigation modes and visual collaborative navigation modes are considered. It is advisable to analyze the collaborative navigation modes in the swarm application of UAVs in precision farming systems, assessing the experience of implementing advanced navigation technologies and innovative development in the field of autonomous precision farming. The experience of implementation and the level of development of collaborative navigation modes in the swarm application of UAVs in precision farming allows us to identify ways to improve the efficiency of UAV interaction in a swarm, taking into account the introduction of precision farming systems in modern conditions.
The possibilities of using artificial intelligence and machine learning to analyze the stock market
Authors:   Surgut State University, Institute of Economics and Management, Surgut, Russia, Varlamova Julia Sergeevna , Zavedeev Egor Vladimirovich
Published: November 2024

Goal. To explore the possibilities of using AI (artificial intelligence) and machine learning in predicting stock prices, bonds, futures, etc. of financial instruments and building optimal investment strategies in stock markets. Problem. Conventional, traditional methods of stock market analysis operate either only within the framework of technical analysis, or only fundamental and are limited in their ability to take into account the actions of economic, political, etc. events when building mathematical models to predict the situation on stock markets. Hypothesis. The use of AI and machine learning to analyze the stock market and predict trends in the prices of financial instruments will improve the accuracy of forecasting, optimize investment strategies, and also help identify risky investments.
Adsorption Mechanism of Heavy Metals Using Activated Carbon Derived from Hydrilla Verticillata
Authors: Tarigan Enda Rasilta , Frida Erna , Humaidi Syahrul , Susilawati Susilawati
Published: November 2024

This research investigates the adsorption mechanism of heavy metals (Cu, Pb, Fe and Zn) using activated carbon derived from Hydrilla verticillata, addressing the critical issue of water pollution caused by heavy metals, which pose significant environmental and health risks due to their persistence and toxicity. The study outlines the preparation process of the activated carbon, which involves washing, drying, carbonization, chemical activation and hydrothermal treatment. Characterization through SEM, EDX, XRD and FTIR analyses confirms the presence of functional groups and an amorphous structure conducive to adsorption. Adsorption tests reveal that H. verticillata-derived activated carbon shows high removal efficiency, especially for lead (Pb), with optimal adsorption capacities achieved within 120 min. The adsorption performance is attributed to a combination of physical adsorption, due to the microporous structure and large surface area, and chemical adsorption, facilitated by functional groups on the carbon surface. This study demonstrates that H. verticillata-derived activated carbon is a viable, cost-effective and environmentally friendly alternative to traditional adsorbents for heavy metal removal from water, with potential applications in sustainable water treatment solutions.
HIGHLIGHTS

Activated carbon derived from the invasive aquatic plant verticillata shows significant potential for heavy metal adsorption in water treatment applications.
Hydrothermally treated activated carbon exhibits enhanced surface morphology, larger surface area and better pore characteristics compared to untreated samples, contributing to its high adsorption capacity.
The study demonstrates that verticillata-derived activated carbon effectively adsorbs Cu, Pb, Fe and Zn, with adsorption efficiencies improving with increased contact time.
The adsorption mechanism involves both physical and chemical interactions, with hydroxyl and carbonyl functional groups playing a crucial role in binding heavy metal ions through complexation and coordination.

GRAPHICAL ABSTRACT
Physicochemical and Structural Properties of Resistant Starch Prepared from Tacca Tuber Starch using Autoclaving-Cooling and Acid Hydrolysis Treatments
Authors: Yonata Diode , Triwitono Priyanto , Arsanti Lestari Lily , Pranoto Yudi
Published: November 2024

Tacca tuber (Tacca leontopetaloides) is a neglected and underutilized plant species. Recently, tacca tuber has been studied as a food plant source of high-amylose starch, so it has the potential to be developed into resistant starch (RS), especially type-3 RS (RS3). RS3 can be prepared through the autoclave-cooling (AC) process, but the RS produced is not optimal. Further increase in RS can be obtained through hydrolysis of citric acid (AH). Until now, systematic knowledge about the preparation method and characterization of RS3 produced from tacca tuber starch through the AC-AH process remains unavailable. This study aims to determine the physicochemical properties and structure of RS3 from tacca tuber starch made through the AC-AH process. Tacca tubers were obtained from the Garut coast, Indonesia. They were first extracted to obtain starch and then processed using the AC process to make RS3. The acquired RS3 was hydrolyzed using AH at various concentrations and hydrolysis times. The results showed that all treatments did not affect the proximate composition, except for water content. Significant effects were observed on amylose and RS levels. The swelling power, solubility, water holding capacity, oil holding capacity and color profile of RS3 also significantly changed. The morphology of RS3 was deformed, accompanied by a change in its crystal structure to a combination of B and V types. This alteration was followed by an increase in the relative crystallinity and thermal profile, while the paste profile decreased significantly. In conclusion, all preparation methods affected the physicochemical properties and structure of RS3 from yam starch, except for the proximate composition. AC-AH treatment with 0.3 M citric acid for 4 h is recommended for preparing RS3 because it produces the highest RS content. The acquired RS3 has the potential to be applied in products that require good paste stability, and have health benefits.
HIGHLIGHTS

Tacca tuber is a neglected and underutilized plant species, a potential source of high amylose starch to be developed into resistant starch type-3 (RS3).
Autoclaving-cooling (AC) and citric acid hydrolysis (AH) treatments produced 32.40 % RS3.
RS3 has an irregular, rough and agglomerate morphological structure.
The crystal structure of RS3 is a combination of types B and V, with a relative crystallinity of 24.38 - 45.94 %.
AC-AH treatment with 0.3 M citric acid for 4 h is recommended in preparing RS3 because it results in the highest RS content.

GRAPHICAL ABSTRACT
Onoceranoid Triterpenes of Lansium domesticum Corr. cv. Kokossan and Their Cytotoxicity against MCF-7 Breast Cancer Cells
Authors: Mayanti Tri , Azahra Salwa Alya , Syafriadi Tasya Putri , Nurlelasari Nurlelasari , Maharani Rani , Julaeha Euis , Supratman Unang , Sinaga Siska Elisahbet , Ekawardhani Savira , Fajriah Sofa
Published: November 2024

The onoceranoid triterpenes isolated from the kokossan fruit peels were studied in vitro using MCF-7 breast cancer cells. Three onoceranoids, namely 8,14-secogammacera-8(26),14-dien-3,21-diol (1), 3β-hydroxyonocera-8(26),14-dien-21-one (2) and α,γ-onoceradienedione (3), were obtained from the ethyl acetate extract of kokossan fruit peels. Compounds 1 - 3 were obtained for the first time from this cultivar. Several spectroscopic methods, including IR, HR-TOFMS and 1,2 D-NMR, were used to determine the chemical structures of compounds (1 - 3), and the results were compared to spectrum data that had previously been published. Additionally, the activity of compounds 1 - 3 was assessed in vitro using MCF-7 cells. With an IC50 value of 17.11 µg/mL, compound 2 demonstrated the highest activity in the activity test findings, followed by compounds 3 and 1, with IC50 values of 19.66 and > 150 µg/mL, respectively. When compared to cisplatin as a positive control, compounds 2 and 3 showed considerable potency, while compound 1 showed no activity. Compounds 2 and 3 were the most promising candidates for the anticancer drug; nevertheless, more testing is necessary to ascertain their biological mechanism for future research.
HIGHLIGHTS

Lansium domesticum is a tropical fruit-bearing tree with significant economic and medicinal value. It has been traditionally used for various ailments, including fever, dysentery, and malaria, due to its rich phytochemical composition.
Kokossan is a cultivar of Lansium domesticum that has not been widely studied for its onoseronoid content, especially in the skin of the fruit. 8,14-sekogammacera-8(26),14-dien-3,21-diol (1), 3β-hydroxyonocera-8(26),14-dien-21-one (2), and α,γ-onoceradienedione (3). For the first time, these two compounds (1 and 2) were separated from this genus; earlier, this compound was the outcome of the reduction (synthesis) of compound 3.
3β-hydroxyonocera-8(26),14-dien-21-one exhibited the highest IC50 value compared to α,γ-onoceradienedione and . 8,14-sekogammacera-8(26),14-dien-3,21-diol.
Compounds 2 and 3 demonstrated potential as anticancer agents, with activity comparable to the standard drug cisplatin. This provides insight that onoceranoids have the potential as chemopreventive agents to treat breast cancer.

GRAPHICAL ABSTRACT
Rapid Micro-Propagation of Disease-Free Hemp (Cannabis sativa L.) to Improve Industrial Production
Authors: Wongchaya Panuphon , Bansra Tatiya , Mahadtanapuk Supuk
Published: November 2024

Hemp (Cannabis sativa L.) is widely used in industrial production due to its pharmacological properties, particularly cannabidiol (CBD). For commercial production, it is essential to have a large-scale propagation that is consistently disease-free and rapid. Thus, this study aims to establish a protocol for exponentially increasing the amount of high CBD hemp variety CA-UP1 by nodal segment via tissue culture method. Initially, with 10-minute surface sterilization with 0.1 % HgCl2, the microbial contamination rate was reduced to its lowest level (approximately 16.67 %) within 7 days. The nodal segments exhibited optimal response to MS media supplemented with 0.5 mg/L TDZ, resulting in a 100 % shoot multiplication rate. The average number of shoots per explant was 4.7 ± 1.57, and the average shoot height was 2.30 ± 0.42 cm at 4 weeks. Following the induction of elongation in MS medium supplemented with charcoal, the seedlings were acclimatized and dipped in a 1,000 ppm IBA solution mixed with talcum powder. The cultivation resulted in a 100 % rooting rate, with an average of 5.6 ± 1.94 roots/explant, an average root length of 5.78 ± 1.96 cm, and an average explant height of 4.32 ± 1.52 cm. The tissue culture protocol can produce over 190 times the quantity of hemp plants compared with the stem cutting technique. The researchers anticipate that this micropropagation protocol will be useful as a rapid and economical alternative for the industrial production of effective C. sativa L.
HIGHLIGHTS

A 10-minute surface cleaning protocol with a minimal microbiological contamination rate of 16.67 % in the nodal segment.
Thidiazuron (TDZ) can stimulate the most significant increase in shoot growth in Cannabis sativa L. variety CA-UP1 when grown on a semi-solid medium.
Dispensing talcum powder combined with IBA results in a 70 - 100 % survival percentage by effectively preventing root during the acclimation stage.
The following procedures can be implemented micropropagation of hemp for the production of a large quantity of high-quality, disease-free hemp plants with approximately 190 times more than stem cutting method.

GRAPHICAL ABSTRACT
La linfogammagrafía en la valoración del edema crónico de los miembros inferiores según nuestra experiencia
Authors: Moreno-Ballesteros Ana , de Bonilla Candau María , Romero Fernández Patricia , Cabaleiro-Burguillos Blanca , Jiménez-Heffernan Amelia
Published: November 2024

El diagnóstico diferencial del edema de los miembros inferiores (MMII) continúa suponiendo un reto, sobre todo en aquellos pacientes sin claras características definitorias de las tres principales etiologías: flebedema, por patología venosa; linfedema, por alteración linfática; y lipedema, por alteraciones del tejido adiposo. Estas tres patologías no solo son las más frecuentes, sino que pueden coexistir, por lo que es necesario recurrir a herramientas diagnósticas para establecer un tratamiento que las abarque. En este sentido, además de la exploración clínica, la linfogammagrafía (LGG) es la prueba recomendada inicialmente por las guías de práctica clínica para realizar dicho diagnóstico diferencial. El objetivo de este trabajo ha sido describir la relación de los hallazgos gammagráficos de los pacientes con edema de MMII sin filiar, pertenecientes al área sanitaria del Hospital Juan Ramón Jiménez de Huelva, España, con los datos clínicos, la exploración física y la respuesta al tratamiento. En la muestra de 21 pacientes hemos podido corroborar el papel crucial de la LGG a la hora de establecer un diagnóstico final, así como intuir la relación entre una afectación linfogammagráfica severa y una peor respuesta al tratamiento. Se necesitan estudios confirmatorios con mayor potencia estadística.
A Comprehensive Framework for Preventing Digital Arrest Scams: Integrating Predictive Crime Script Models, Cognitive Resilience, Advanced Forensics, and Public Awareness
Authors: Manoj Kumar
Published: November 2024

Digital arrest scams, in which fraudsters impersonate law enforcement to intimidate victims into financial compliance, are an escalating threat. This research aims to propose an integrated framework that merges four critical areas: predictive crime script modeling, cognitive resilience strategies, advanced forensic tools, and digital literacy initiatives. By leveraging these approaches, this paper aims to enhance law enforcement capabilities, improve victim decision-making processes, advance forensic investigations, and foster public awareness to prevent digital arrest scams. We further explore the application of artificial intelligence (AI), big data, and blockchain in these domains to support future developments and enhance cybersecurity measures
Demand for Malaria Prevention and Treatment among Households in the Federal Capital Territory, Nigeria
Authors: Abraham Ayodeji Dr. Daniel , Seleem Babajide Dr. Alabi , Akindunjoye Daniel Akinboro , Kehind MS. Nike , Abayomi Lawal Dr. Habib , Omede Dr. Owen
Published: November 2024

Background: In Nigeria, malaria remains a public health concern, necessitating the examination of household spending on treatment and prevention. Despite various initiatives, Nigeria still has high malaria-related mortality, prompting this study to clarify the link between household demand for malaria treatment and prevention. The dependent variable is yearly malaria-related spending with independent variables are education, head of household income, age, environmental factor, spouse’s income and cost of prevention/treatment Method: Using primary and secondary data, this cross-sectional study gathered information through household observations and structured questionnaires. Of 400 samples distributed, 381 were completed and returned, focusing on household background and the demand for malaria treatment and prevention products. Results: The logit regression model analyzed the potential associations among variables such as age, household head income, spouse’s income, education, environmental factors, and malaria occurrence. It found that education and household head income were statistically significant at a p-value of 0.05, indicating a meaningful relationship with malaria incidence. No multicollinearity was detected among the variables. Conclusion: The study titled “Demand for Malaria Prevention and Treatment Among Households in the Federal Capital Territory, Nigeria” found that household income and education significantly influence spending on malaria prevention and treatment. These findings underscore the critical role of both education and economic capacity in shaping households’ efforts to combat malaria, emphasizing the need for policies that enhance these factors to improve malaria prevention and treatment outcomes.
Environmental Stress and Social Dynamics: Analyzing the Long-term Effects of Rohingya Refugee Influx in Bangladesh
Authors: Ali Mohammad , Shahreen Tanzima
Published: November 2024

The Rohingya refugee crisis has profoundly impacted Bangladesh, particularly in the Cox’s Bazar region, where over one million refugees have sought shelter since 2017. This paper examines the environmental footprint and social implications of this influx, focusing on the challenges and opportunities it presents. The environmental analysis reveals significant deforestation, soil erosion, and strain on water resources due to the establishment of refugee camps (UNDP, 2018; ReliefWeb, 2018). These changes have increased the risk of natural disasters such as landslides and flooding, necessitating sustainable management strategies. Socially, the influx has altered demographic dynamics, intensified competition for resources, and strained relationships between refugees and host communities (Frontiers, 2022; USIP, 2023). Economic impacts include wage depression and market instability, exacerbating existing vulnerabilities in the host community (Tandfonline, 2020). Educational challenges persist for both refugee and local children due to limited access to quality education (Human Rights Watch, 2019). The study highlights the need for comprehensive policy responses that integrate environmental management with social cohesion initiatives. Recommendations include enhancing international cooperation to support Bangladesh’s efforts in managing the crisis effectively. Future research should focus on long-term environmental monitoring, economic impact assessments, and strategies for improving health care and education access for both populations. By addressing these areas, stakeholders can develop informed policies that promote sustainable development and social stability in Cox’s Bazar.
Role of CCRT In T3n0 Squamous Cell Carcinoma Larynx, Pros Vs Cons
Authors: Khan Ayesha , Naeem Riaz  , Faisal Manzoor  , Kamran Zamurrad Malik  , Shakeel Ahmed  , Muhammad Ali
Published: November 2024

Objective: To assess the use and efficacy of Concurrent Chemoradiotherapy for a T3N0 Laryngeal Cancer as a Laryngeal Function Preservation modality.Study Design: Prospective Study designPlace and Duration of Study: CMH Rawalpindi, Pakistan from January 2022-January 2023.Methodology: The sample size was n=24, having TPF-CCRT from January 2022 to January 2023 was chosen by using a purposive sampling technique. Individuals were having abnormalities of T3 glottis without vocal cord fixation. Along with MRI, the pretreatment evaluation also comprised clinical, endoscopy, and ultrasound examinations with or without fine needle pick cytology samples. Moreover, F-fluoro-2-deoxy-D-glucose positron emitting tomography was used for whole-body CT scanning. The UICC TNM grading method was used to grade the tumors as grade 15.Results: Twelve out of 24 patients had grade 1 tumor (50%), eight had grade 2 tumors (25%), and four had grade 3 tumors (25%). There had been complete resolution among 17 (70%) of patients, while the disease remains persistent disease in 7 (30%) patients. 95% of patients found with good speech and breathing. 95% of patient organs remain preserved. All 24 patients received CCRT. Four individuals (20%) without tumor regression received surgery following 40 Gy of RT. Others received RT with a 66 Gy median total dose.Conclusion: The study found that effective cancer control is possible with CCRT, and its effects are manageable in 70% of patients with tolerable toxicity. However, in 30% of cases, it fails, requiring salvage laryngectomy. However, the search for a viable strategy with tolerabl
The Aesthetics of Belonging: Indigenous Urbanism and City Building in Oil-Boom Luanda
Authors: Gastrow Claudia
Published: November 2024

After centuries of colonial rule, the end of Angola's three-decade civil war in 2002 provided an irresistible opportunity for the government to reimagine the Luanda cityscape. Awash with petrodollars cultivated through strategic foreign relationships, President José Eduardo dos Santos rolled out a national reconstruction program that sought to transform Angola's capital into what he considered to be a modern, world-class metropolis. Until funds dried up in 2014, the program—in conjunction with sweeping private investments in real estate—involved mass demolitions of vernacular architecture to make way for high-rise buildings, large-scale housing projects, and commercial centers. The program thus underestimated the values enshrined in the materials and designs of Luanda's existing "informally" constructed neighborhoods, or musseques. The Aesthetics of Belonging explores the political significance of aesthetics in the remaking of the city. Claudia Gastrow's archival and ethnographic work, which includes interviews with city planners, architects, nonprofit leaders, and urban dwellers, shows how government infrastructure projects and foreign-inspired designs came to embody displacement and exclusion for many. This, Gastrow argues, catalyzed a countermovement, an aesthetic dissent rooted in critically reframing informal urbanism as Indigenous—a move that enabled the possibility of recognizing the political potential of informal settlements as spaces that produce belonging.
Emerging trends in coffee consumption among university students in Béjaïa, Algeria
Authors: Hamitri-Guerfi Fatiha , Bachir-Bey Mostapha
Published: November 2024

Background: In Algeria, coffee consumption, being restricted to the morning and afternoon, is commonly associated with enhancing daily activities and maintaining health. However, the specific patterns of coffee consumption and related health implications within the university environment remain underexplored. Aims: This study aimed to investigate coffee consumption patterns, including frequency, preferred preparation methods, and perceived health benefits, among university students in Algeria. Participants and Methods: A cross-sectional survey was conducted among 254 university students aged 18 to 50. Data was collected through self-administered questionnaires distributed during lectures. Results: The results revealed that 90.9% of the surveyed students consumed coffee regularly. Among regular coffee drinkers (81.8%), 18.2% were classified as high consumers, consuming an average of three cups per day. The majority of students (79.9%) added sugar to their coffee, with 34.6% adding two spoons and 22% adding more than two spoons. Conclusion: Statistical analysis indicated a positive correlation between age, educational level, and coffee consumption frequency. As individuals age and advance in their education, their reliance on coffee tends to increase. These findings highlight the significance of coffee consumption within the university environment and underline the need for further research to explore the potential health impacts of excessive coffee intake.

Keywords: Coffee consumption pattern, eating behavior, university students, Bejaia province.