bluuebunny/crossref_metadata_2025 huggingface dataset:
Humanism, Anti-Authoritarianism, and Literary Aesthetics
Authors: Schulenberg Ulf
Published: December 2023

Presenting pragmatist humanism as a form of anti-authoritarianism, this book sheds light on the contemporary significance of pragmatist aesthetics and the revival of humanism.

asThis interdisciplinary study shows that a mediation between pragmatist aesthetics – which emphasizes the significance of creating, making, and inventing – and Marxist materialist aesthetics – which values form – promises interesting results and that the former can learn from the latter.add

In doing so, Ulf Schulenberg discusses 3 layers of the multi-layered phenomenon that is the revival of humanism: He first explains the potential of a pragmatist humanism, clarifying the contemporary significance of humanism. He then argues that pragmatist humanism is a form of anti-authoritarianism. Finally, he shows the possibility of bringing together the resurgence of humanism and a renewed interest in the work of aesthetic form by arguing that pragmatist aesthetics needs a more complex conception of form.

Establishing a transatlantic theoretical dialogue, Humanism, Anti-Authoritarianism, and Literary Aesthetics brings together literary and aesthetic theory, philosophy, and intellectual history. It discusses a broad range of authors – from Emerson, Whitman, James, Nietzsche, Proust, and Dewey to Wittgenstein, Lukács, Adorno, Jameson, Latour, and Rorty – to illuminate how humanism, pragmatism, and anti-authoritarianism are interlinked.
The Rebellion of Forms in Modern Persian Poetry
Authors: Sonboldel Farshad
Published: December 2023

An analysis of the aesthetic, cultural and political aspects of alternative poetic movements and individual poets in three periods: the Constitutional Revolution (1900–1920), the post-constitutional era (1920–1940), and the ascendency of modernism (1940–1960).

Farshad Sonboldel shines new light on the history of modern Persian poetry by re-imagining the roles that the aesthetic experimentations of alternative poets played in different phases of the literary revolution in modern Persian poetry. Dominant narratives portray modern Persian poetry as a gradual, rational, and moderate change in the classical regime of aesthetics as well as a response to – and reflection of – cultural and socio-political changes within Iranian society. They also disregard the significance of radical experiments by alternative poets and undervalue the part they played in the initiation and progress of the so-called "literary revolution." These mainstream narratives minimize the socio-political engagement of literary works with the direct reflection of the social reality, and thus neglect the way many alternative poems struggle with socio-political issues through deconstructing the old and constructing new aesthetic systems.

Each chapter of The Rebellion of Forms in Modern Persian Poetry is centred around poems chosen for their potential to showcase notable experiments of pioneer movements and individuals in each given period. Examining the formal and thematic aspects of these poems, this book reformulates the story of modern Persian poetry and unravels the relationship between radical aesthetic changes in the practice of poetry and resistance against political and cultural domination in society.
Screenwriting
Authors: Gulino Paul Joseph
Published: December 2023

A substantial update of the previous edition, Screenwriting: The Sequence Approach deconstructs recent feature films and offers a new section analysing popular television series.

A proven screenwriting method in emotionally engaging an audience, the sequence approach emphasises the underlying motives of each story plot to better convey its relation to the work as a whole. In this expanded second edition, Paul Gulino includes analyses of recent noteworthy films and serial dramas, such as Parasite, Barry and Breaking Bad, with an eye to how they manage audience attention, convey vital information and deliver their emotional payloads. The aim of the book is to help writers move readily from the feature film to the serial form, mastering both. It is perfect for both beginning writers and those with experience in the feature screenplay form.
Prescription for Inequality
Authors: Duquaine-Watson Jillian M.
Published: December 2023

This book explores how social determinants of health (SDH) impact the health of a variety of marginalized demographic groups in the United States. Chapters focus on the 13 groups that research demonstrates are most disadvantaged by SDH and, consequently, who suffer the most from ongoing health disparities in America. This includes Black and Hispanic individuals, the LGBTQIA+ community, women, the elderly, people with disabilities, veterans, and those living in rural areas, among others.

Chapters follow a standardized format that makes it easy for readers to focus in on aspects of the subject that are of greatest interest. Each profile begins with a snapshot of that group’s current state of health, including the biggest medical concerns and how other determinants of health may play a role. Next, each chapter takes an in-depth look at the four components of SDH: economic factors, educational access and quality, healthcare access and quality, and living environment and social context. Unique problems and possible solutions are explored within each of these four sections. An end-of-volume bibliography and further readings list points readers who wish to continue their investigation of the topic toward additional information.

Relying on an interdisciplinary framework, the book incorporates research from diverse fields including public health, feminist theory, critical studies of race and ethnicity, poverty studies, disability studies, aging studies, cultural competence, legal studies, and global health. In recognition of the reality that health disparities are the result of a complex interplay of forces and structural factors that permeate American culture, analysis extends beyond health and health care to include a broad range of interrelated social, political, economic, and educational components.
An analysis coordinate transform to facilitate use of in-situ aircraft observations for flux estimation
Authors: Tribby Ariana L. , Wennberg Paul O.
Published: December 2023

Abstract. Analysis of aircraft observations of atmospheric trace gases is key towards improving our understanding of fundamental chemical processes and quantifying anthropogenic emissions. A common approach for such analysis is use of chemical transport models to produce 4-D fields for comparison with these observations together with various inversion techniques to constrain the underlying fluxes and chemistry. Yet, time and monetary constraints of expensive computational jobs for chemical transport modelling can be a significant hindrance. Here, we show the advantages of using potential temperature as a dynamical coordinate to compare such simulations to aircraft observations of trace gases whose concentration fields are strongly influenced by synoptic-scale transport. We use global observations of ethane and propane from the Atmospheric Tomography (ATom) aircraft mission and simulate global mole fractions for these gases using GEOS-Chem High Performance v13.4.1. We show, using potential temperature as an analysis coordinate, that Bayesian estimates of the fluxes of these gases in the Northern Hemisphere are largely invariant (± 10 %) even as the simulation spatial resolution is increased 100-fold. Our approach can have broad applications for the modelling of trace gases in the extra-tropics, particularly those with lifetimes long compared to synoptic timescales.
On the potential of a low-complexity model to decompose the temporal dynamics of soil erosion and sediment delivery
Authors: Matthews Francis , Panagos Panos , Fendrich Arthur , Verstraeten Gert
Published: December 2023

Abstract. Testing and improving the capacity of soil erosion and sediment delivery models to simulate the intra-annual dynamics climatic drivers and disturbances (e.g. vegetation clearcutting, tillage events, wildfires) is critical to understand the drivers of the system variability. In seasonally changing agricultural catchments, explicit temporal dynamics are typically neglected within many soil erosion modelling approaches, in favour of a focus on the long-term annual average as the predictive target. Here, we approach the trade-off between the need for model simplicity and temporally-dynamic predictions by testing the ability of a low-complexity, spatially distributed model (WaTEM/SEDEM), to decompose the 15-day dynamics of soil erosion and sediment yield. A standardised parameterisation and implementation routine was applied to four well-studied catchments in North-West Europe with open-access validation data. Through the testing of several alternative model spatial and connectivity structures, including the addition of an empirical runoff coefficient, we show that a temporally-static calibration of transport capacity cannot adequately replicate the relative seasonal decoupling of gross (on-site) soil erosion and sediment delivery. Instead, embedding seasonality into the calibration routine significantly improved the model performance, revealing a negative relationship between gross (pixel-scale soil displacement) and net erosion (stream channel sediment load) throughout the year. By incorporating temporal dynamics, the relative net effect is a reduction in the magnitudes of the spatially-distributed sediment fluxes at aggregated timescales, compared to a temporally-lumped approach. Published catchment observations infer that the efficacy of sediment delivery via overland flow is strongly reduced in the summer by abundant vegetative boundaries and increased in the winter via soil crusting and its promotion of runoff. Models operating at temporally-aggregated timescales should account for the possibility of decoupling in time and space between gross erosion and sediment delivery in arable catchment systems, related to alternations between transport- and detachment-limited sediment transport capacity states. Despite the complexities involved in the temporal downscaling of WaTEM/SEDEM, we show the utility of this approach to: 1) identify key missing information components requiring attention to reduce error in gross erosion predictions (e.g. more consideration of antecedent soil conditions), 2) form a basis for strategically adding physical process-representation, with a focus on maintaining low model complexity while improving predictive skill, and 3) better understand the spatial and temporal interdependencies within soil erosion models when undertaking upscaling exercises.
Extending wind profile beyond the surface layer by combining physical and machine learning approaches
Authors: Liu Boming , Ma Xin , Guo Jianping , Li Hui , Jin Shikuan , Ma Yingying , Gong Wei
Published: December 2023

Abstract. Accurate estimation of the wind profile, especially in the lowest few hundred meters of the atmosphere, is of great significance for weather, climate and renewable energy. Nevertheless, the Monin–Obukhov similarity theory fails above the surface layer over the heterogeneous underlying surface, resulting in an unreliable wind profile obtained from the conventional extrapolation methods. To solve this problem, we propose a novel method that combines the power law method (PLM) with the random forest (RF) algorithm to extend wind profiles beyond the surface layer, called the Phy-RF method. The underlying principle is to treat the wind profile as a power law distribution in the vertical direction, in which the power law exponent (α) is determined by the Phy-RF model. First, the Phy-RF model is constructed based on the atmosphere sounding data at 119 radiosonde (RS) stations across China and in conjunction with other data such as surface wind speed, land cover type, surface roughness, friction velocity, geographical location, and meteorological parameters from June 2020 to May 2021. Afterwards, the performance of the Phy-RF, PLM and RF methods over China are evaluated by comparing them with RS observations. Overall, the wind speed at 100 m of the Phy-RF model exhibits high consistency with RS measurements, with a correlation coefficient (R) of 0.93 and a root mean squared error (RMSE) of 0.92 m s−1. By contrast, the R and RMSE of wind speed results from PLM (RF) method are 0.87 (0.91) and 1.37 (1.04) m s−1, respectively. This indicates that the estimates from the Phy-RF method are much closer to observations than those from the PLM and RF methods. Moreover, the RMSE of the wind profiles estimated by the Phy-RF model is relatively larger at highlands, while is small in plains. The result indicates that the performance of the Phy-RF model is affected by the terrain factor. Finally, the Phy-RF model is applied to three atmospheric radiation measurement sites for independent validation, and the wind profiles estimated by the Phy-RF model are found consistent with the Doppler Lidar observations. This confirms that the Phy-RF model has good applicability. These findings have great implications for the weather, climate and renewable energy.
Validated probabilistic approach to estimate flood direct impacts on the population and assets on European coastlines
Authors: Duo Enrico , Montes Juan , Le Gal Marine , Fernández-Montblanc Tomás , Ciavola Paolo , Armaroli Clara
Published: December 2023

Abstract. This work presents the approach used to estimate coastal flood impact, developed within the EU H2020 European Coastal Flood Awareness System (ECFAS) Project, for assessing flood direct impacts on population, buildings, and roads along the European coasts. The methodology integrates object-based and probabilistic evaluations to provide uncertainty estimates for damage assessment. The approach underwent a user-driven co-evaluation process, it was applied to 16 test cases across Europe and validated against reported impact data in three major reference cases. A comparison with grid-based damage evaluation methods was also conducted. The findings demonstrate that the ECFAS Impact approach offers valuable estimates for affected populations, reliable damage assessments for buildings and roads, and improved accuracy compared to traditional grid-based approaches. The methodology also provides information for prevention and preparedness activities, facilitates further evaluations of risk scenarios and cost-benefit analysis of disaster risk reduction strategies. The approach is a tool suitable for large-scale coastal flood impact assessments, offering improved accuracy and operational capability for coastal flood forecasts. It represents a potential advancement of the existing EU-scale impact method used by the European Flood Awareness System (EFAS) for riverine flood warnings. The integration of object-based and probabilistic evaluations, along with uncertainty estimation, enhances the understanding and management of flood impacts along the European coasts.
Modeling unsteady loads on wind-turbine blade sections from periodic structural oscillations and impinging gusts
Authors: Wei Nathaniel James , Shende Omkar Bhalchandra
Published: December 2023

Abstract. Many traditional methods for wind turbine design and analysis assume quasi-steady aerodynamics, but atmospheric flows are inherently unsteady and modern turbine blades are susceptible to aeroelastic deformations. This study therefore evaluates the effectiveness of simple analytical models for capturing the effects of such unsteady conditions on wind-turbine blades. We consider a pitching and plunging airfoil in a periodic transverse gust as an idealization of unsteady loading scenarios on a blade section. A potential-flow model derived from a linear combination of canonical problems is proposed to predict the unsteady lift on a two-dimensional airfoil in the small-perturbation limit. We then perform high-fidelity two-dimensional numerical simulations of a NACA-0012 airfoil over a range of periodic pitch, plunge, and gust disturbances, and quantify the amplitude and phase of the unsteady lift response. Good agreement with the model predictions is found for low to moderate forcing amplitudes and frequencies, while deviations are observed when the angle-of-attack amplitudes approach the static flow-separation limit of the airfoil. Potential explanations are given for the cases in which the ideal-flow theory proves insufficient. This theoretical framework and numerical evaluation motivate the inclusion of unsteady flow models in design and simulation tools in order to increase the robustness and operational lifespans of wind turbine blades in real flow conditions.
El aliento de vida de Banebdjedet: expresando una antigua creencia mortuoria egipcia en el periodo romano
Authors: Ortiz García Jónatan
Published: December 2023

Los estudios de los últimos años sobre las creencias osirianas en época romana han permitido acceder, a través de las prácticas reflejadas en los ajuares funerarios, a una esfera religiosa en apariencia homogénea, pero que experimentó cambios fruto de la propia evolución interna y no únicamente por los contactos culturales de la época. En este contexto se presenta este estudio sobre un concepto mortuorio que implica a uno de los animales sagrados mejor documentados (también en la literatura grecolatina): el carnero de Mendes, Banebdjedet. En los testimonios recogidos, que se estudian como conjunto por primera vez, dicha manifestación divina proporciona el hálito de vida necesario para la resurrección a los difuntos. El concepto está atestiguado escasamente, pero tuvo una expansión regional relativamente relevante y una perduración importante.
Aboriginal prisoners with cognitive impairment: Is this the highest risk group?
Authors: Shepherd Stephane , Ogloff James , Paradies Yin , Pfeifer Jeffrey
Published: December 2023

Early estimates point to higher rates of cognitive impairment among Indigenous Australians in custody compared to non-Indigenous Australians. This study sought to examine the prevalence of cognitive impairment in a representative sample of Indigenous offenders from Victorian prisons. Differences in mental illness prevalence, offending history and post-release recidivism were explored by presence of cognitive impairment. Results revealed an over-representation of cognitively impaired prisoners in the sample and a large minority with concomitant mental illness or disability. Cognitively impaired prisoners were more likely to re-offend, were younger at first offence, and had greater numbers of prior offences. Findings signal the need for culturally themed disability assistance and diversionary options at all levels of the criminal justice system.
Non-market distribution serves society in ways markets cannot: A tentative defense of food charity from small-town New England
Authors: Bliss Sam , Hill Ava , Bramsen Alexandra , Graziano Raven , Perez Sahagun Saharay , Krivak-Tetley Flora
Published: December 2023

It has become fashionable to call for ending food charity. Anti-hunger activists and scholars advocate instead for ensuring through government programs that everybody has enough money or vouchers to purchase all the food they need. Their criticisms rightly denounce charitable food for being incapable of eradicating hunger, but they neglect the advantages that charity confers as a non-market food practice—that is, an activity that produces or distributes food that is not for sale. Our interviews with non-market food practitioners in the Brattleboro, Vermont, area demonstrated that distributing food for free strengthens relationships, fosters resilience, puts edible-but-not-sellable food to use, and aligns with an alternative, non-market vision of a desirable food future. Interviewees suggested that market food systems, in which food is distributed via selling it, cannot replicate these benefits. Yet food pantries and soup kitchens tend to imitate supermarkets and restaurants—their market counterparts—since purchasing food is considered the dignified way to feed oneself in a market economy. We suggest that charities might do well to emphasize the benefits specific to non-market food rather than suppressing those benefits by mimicking markets. But charities face limits to making their food distribution dignified, since they are essentially hierarchies that funnel gifts from well-off people to poor people. Food sharing among equals is an elusive ambition in this highly unequal world, yet it is only by moving in this direction that non-market food distribution can serve society without stigmatizing recipients.
Infrastructure planning emergency levels of service for the Wellington region, Aotearoa New Zealand – An operationalised framework
Authors: Mowll Richard , Becker Julia , Wotherspoon Liam , Stewart Carol , Johnston David , Neely Daniel
Published: December 2023

‘Planning Emergency Levels of Service’ (PELOS) are goals for the delivery of infrastructure services following a major hazard event, such as an earthquake or flood. This paper presents an operationalised PELOS framework for the Wellington region based on interviews with emergency and critical infrastructure managers and discusses important changes from the preliminary to the operationalised framework. A shared understanding of these PELOS will help Wellington region infrastructure providers, emergency management professionals and the potentially impacted communities plan for major events. PELOS for the energy, telecommunications, transport, and water sectors have been developed, and high-level interdependencies considered. The PELOS framework can be updated for other regions, by the critical infrastructure entities and emergency managers, using locally relevant hazard scenarios. In turn, this approach can inform the end-users (communities) of the goals of the critical infrastructure providers following a major hazard event.
Fatores associados à mortalidade neonatal precoce
Authors: Silva Lucilânia Maria de França , Pereira Milena Camila de Souza Wanderley , Bulhões Camilla de Sena Guerra , De Oliveira Aline Silva , De Oliveira Scarlletie Rodrigues Perreli Batista , Sette Gabriela Cunha Schechtman , Lima Ana Paula Esmeraldo
Published: December 2023

A taxa de mortalidade neonatal reflete as condições de saúde de uma população. No Brasil, a elevada taxa revela que há um problema de saúde pública, especialmente na região Norte e Nordeste. Objetivo: Investigar os fatores associados ao óbito neonatal precoce no estado de Pernambuco. Método: Estudo descritivo, transversal e quantitativo. A população foi composta por todos os óbitos neonatais ocorridos no estado de Pernambuco no ano de 2017. Os dados foram coletados a partir do banco de dados do projeto mestre, oriundos do Sistema de Informação de Mortalidade cedidos pela Secretaria de Saúde de Pernambuco. Realizou-se análise descritiva com o auxílio do programa PSPP; para a análise dos fatores associados, aplicou-se o teste Qui-quadrado ou o Exato de Fisher. Resultados: Foram analisados 1151 óbitos, que mostraram associação da mortalidade neonatal precoce com idade e escolaridade materna, residência na região metropolitana, tipo de gravidez e parto, filhos anteriores, sexo do recém-nascido, peso ao nascer, prematuridade e local de ocorrência do óbito. Conclusão: Ser filho de mãe adolescente, com menos de 8 anos de estudo, residente na região metropolitana, nascido de parto vaginal, primogênito, do sexo feminino, prematuro e com baixo peso ao nascer apresenta maior risco de óbito na primeira semana de vida.
Spor Bilimleri Öğrencilerinin Serbest Zaman İlgilenimleri ve Yaşam Doyumları Arasındaki İlişkinin İncelenmesi
Authors: AKTOP Mustafa , GÖKSEL Ali Gürel
Published: December 2023

Çalışmanın amacı; Spor Bilimleri Fakültesi öğrencilerinin serbest zaman ilgilenimleri ve yaşam doyumları arasındaki ilişkinin incelenmesidir. Çalışmanın problem cümlesi; Spor Bilimleri Fakültesi öğrencilerinin serbest zaman ilgilenimlerinin yaşam doyumları üzerinde etkisi var mıdır? Araştırmanın evrenini; Muğla Sıtkı Koçman Üniversitesi, Spor Bilimleri Fakültesi öğrencileri oluşturmuştur. Örneklemini ise; rastgele örnekleme yöntemi ile tüm bölümlerden seçilen 102’si kadın 159’u erkek olmak üzere toplamda 261 öğrenci oluşturmaktadır. Çalışmada veri toplama aracı olarak; araştırmacılar tarafından hazırlanan kişisel bilgi formu, Kyle vd., (2007) tarafından geliştirilen “Serbest Zaman İlgilenim Ölçeği” ve Diener vd., (1985) tarafından geliştirilen “Yaşam Doyum Ölçeği” kullanılmıştır. Ulaşılan verilerin demografik özelliklerini belirlemek amacıyla frekans ve yüzde analizi, ölçek puanlarının normal dağılıp dağılmadığını belirlemek için basıklık (kurtosis) ve çarpıklık (skewness) analizleri, değişkenler arasındaki ilişkiyi tespit etmek amacıyla t-testi ve ANOVA testleri ve iki değişken arasındaki ilişkiyi tespit etmek amacıyla pearson korelasyon testi yapılmıştır. Araştırma sonucunda; Spor Bilimleri Fakültesi öğrencilerinin serbest zaman ilgilenimlerinin yaşam doyumu üzerinde doğrudan ve olumlu yönde etkili olduğu bulunmuştur.
Sicherheit und Kommunikation bei Fußballgroßveranstaltungen
Authors: Kubera Thomas
Published: December 2023

Sicherheit rund ums Spiel

Fußballspiele locken jedes Jahr Millionen von Zuschauern in die Stadien. Damit werden sie nicht nur zu spektakulären Großveranstaltungen, sondern auch zu Orten der großen Emotionen und der Begegnung unterschiedlicher Fankulturen. Schon angesichts der Menschenmengen stellen die Durchführung und Sicherung jeder Fußballbegegnung personelle wie infrastrukturelle Herausforderungen für die Veranstalter und die öffentlichen Sicherheitsakteure dar.

Sicherheit verbessern

Das Praxishandbuch ermöglicht den Akteuren der Sicherheitsgewährleistung im Fußball, den eigenen Standort zu bewerten, Optimierungsmöglichkeiten zu identifizieren und entsprechend umzusetzen. Mit Hilfe der Handlungsempfehlungen kann eine möglichst effektive Sicherheitsgewährleistung unter Beachtung der Freiheitsansprüche von Fans, Zuschauern und im Interesse der weiteren Öffentlichkeit erreicht werden.

Die Beiträge sind wie in einem Lexikon von A bis Z geordnet und folgen einer einheitlichen Darstellung: Zu Beginn wird jeweils das Schlagwort in Form einer Definition erläutert. Umfassenderen Beiträgen wird zusammen mit der Definition eine kurze Zusammenfassung der thematisierten Inhalte vorangestellt. Komprimierte Empfehlungen sind besonders hervorgehoben.

Die Abschnitte sind so gestaltet, dass sie mit wenig Zeitaufwand gelesen werden können, aber gleichzeitig umfassend informieren. Querverweise innerhalb der Beiträge stellen Zusammenhänge zwischen den Begriffen bzw. den Artikeln her, betten sie in einen größeren Gesamtzusammenhang ein und ermöglichen, sich intensiv mit verschiedenen Aspekten einer Thematik auseinanderzusetzen.

Für Praxis und Ausbildung

Das Handbuch richtet sich an alle involvierten Akteure in Praxis und Ausbildung
From Past to the Future of fMRI in Pediatrics: A Bibliometric Analysis
Authors: Rahnemayan Sama , Habibi Parinaz , Ali Akbari Khoei Reza , Lotfi Alireza , Ghojazadeh Morteza
Published: December 2023

Context: The use of functional magnetic resonance imaging (fMRI) in the evaluation of children's brains is becoming increasingly popular. However, due to the high number of publications, it's nearly impossible to read all the related articles and become aware of the crucial elements or the best approach to invest time and effort in this field. Objectives: Our goal was to gain a better overall understanding of fMRI publications and to use this information in policy and management contexts to make more efficient decisions. Methods: Data were downloaded from Scopus from the 1990s to the end of 2021 based on the theme of fMRI in pediatrics. The retrieved research articles were analyzed with the Bibliometrix package in R software. Results: From 8,544 documents written by 25,697 authors, the USA is by far the most productive country with a total of 3,609 publications. However, regarding the average article citations, Sweden is at the top of the list, with 77.79 average citations. Important themes include emotion, autism spectrum disorders, attention-deficit/hyperactivity disorders, and childhood maltreatment. Conclusions: The results of the present study on fMRI research in the field of pediatrics will be helpful for professionals to visually understand the pediatric modes and trends in fMRI.
Advances in the Use of Nanomaterials in Tumour Therapy: Challenges and Prospects
Authors: Yang Hongmei , Li Chen , Xie Qiang
Published: December 2023

Nanomaterials have shown great potential in anti-tumor applications and are currently the focus of research. This review article aims to provide a comprehensive overview of the challenges encountered in oncology treatment and how nanomaterials are being utilized to overcome these obstacles. The authors discuss the limitations of conventional treatments, including limited efficacy, side effects, and toxicity issues. They highlight the importance of early tumour diagnosis and personalized treatment plans, as well as the need for innovative therapeutic approaches such as targeted therapy, immunotherapy, and gene therapy. The article primarily focuses on how nanomaterials can be engineered to achieve specific recognition and aggregation within tumour tissues through surface modifications involving targeting molecules such as antibodies, peptides, and receptor ligands. This surface modification technique facilitates improved targeting in the targeting of photodynamic therapy, while minimizing harm to normal tissues. The authors also discuss the potential and future prospects of nanomaterials in tumour therapy, including breakthroughs in their application, biosafety concerns, biocompatibility issues, preparation processes, clinical translation challenges, interdisciplinary cooperation, international exchange, relevant regulations and ethical guidelines. Overall, this review highlights the substantial potential of nanomaterials in oncology treatment, emphasizing the need for careful consideration of safety concerns to ensure their safe and effective application. The authors conclude that strengthening interdisciplinary cooperation and international exchange will contribute to the healthy development of nanomaterials in oncology treatment.
The Porch and its Interaction with Building Design in Arid Zones
Authors: Berghout Belkacem , Berghout Walid , Berghout Imene
Published: December 2023

Improving the energy performance of buildings has thus become a major challenge, as the building sector is now one of the main sources of energy consumption and one of the main contributors to greenhouse gas emissions. Faced with these alarming challenges, current building design in the north is based on minimizing heat loss. However, this logic is not necessarily the most relevant in southern countries, characterized by excessive heat and insufficient, variable rainfall. The best way to achieve this is through sustainable design, with its intrinsic, energy-saving qualities, exploited by effective modeling. This article focuses on ideas and innovations that are helping to overcome these challenges. The results of introducing a porch into building design represent best practice in arid zones and beyond in terms of how it is thermally insulated. This has resulted in a significant reduction in thermal load in the energy ratio of up to 53.55%. This latest research aims to provide construction professionals with concrete examples of the design process, its technical feasibility, optimization and digitization based on climatic data from the arid zone.
Implementasi Sistem Informasi Pemerintah Daerah: Apakah Efektif Dalam Mendukung Pelaporan Keuangan OPD
Authors: Dwidya Nitasya  , Lilik Handajani  , Widia Astuti
Published: December 2023

This study aims to determine how effective the implementation of local government information systems (SIPD) in supporting financial reporting at OPDs in Mataram City, namely RSUD X. This research uses descriptive qualitative methods with data collection techniques in the form of observations and interviews. The research analysis refers to the UTAUT effectiveness indicators consisting of Performance Expectancy, Effort Expectancy, Social Influences and Facilitating Conditions. The results of this study indicate that the implementation of SIPD in supporting financial reporting at RSUD X when viewed in terms of indicators of performance expectancy, effort expectancy and facilitating conditions is still less effective because in its implementation SIPD still has many weakness both in terms of system stability and the availability of features needed, while for indicators of social influences SIPD can already be categorized as effective because the implementation of financial report data entry is adapted to user needs.
Levantamento das espécies frutíferas em áreas de agricultura familiar no município de Santarém, Pará
Authors: Rayol Yasmin , Cristovão Eduarda Emilia Magalhães , Romano Maria Lita Padinha Correa
Published: December 2023

As espécies frutíferas se apresentam como estratégia importante para garantia da segurança e soberania alimentar de populações tradicionais. O objetivo do trabalho foi estimar a riqueza e registrar as espécies frutíferas cultivadas em quintais de agricultura familiar no município de Santarém, Pará. O levantamento das espécies frutíferas foi realizado em 13 quintais das famílias visitadas. Foram registrados 520 indivíduos pertencentes a 39 espécies, 29 gêneros e 16 famílias botânicas. Destacaram-se as famílias Arecaceae (6 spp.) e Myrtaceae (5 spp.). Em média foram encontradas 14 espécies frutíferas por quintal, evidenciando que o cultivo dessas espécies nos quintais está fortemente associado ao suprimento da demanda alimentos para o consumo familiar. As espécies Persea americana (100%), Cocos nucifera (100%) e Theobroma grandiflorum (92%) foram as mais frutíferas mais frequentes. A riqueza de espécies frutíferas encontrados nos quintais das famílias visitadas revela a importância desses ambientes na soberania e segurança alimentar e nutricional.
Composição físico-química de sucos de uva elaborados na região do Planalto Norte Catarinense, safra 2021
Authors: Schmidt Eduarda , Maciel Thalia Aparecida Silva , Kowal Alcemir Nabir , Almeida Rabechlt Stange , Jansen Thuany Levandoski , Farias Eduardo Virmond Souza , Altmann Henry Matheus , Steidel Otavio Frederico , Palinguer Rodrigo , Demetrio Kelly Eduarda , Krauss Naira Marina , Würz Douglas André
Published: December 2023

Devido à viticultura ser uma atividade em processo de consolidação na região do Planalto Norte Catarinense, os produtores não realizam um acompanhamento da qualidade físico-química dos seus produtos, com o objetivo de comparar e atender a legislação brasileira vigente e os padrões de qualidade. Neste contexto, o objetivo deste trabalho foi realizar a caracterização físico-química de sucos de uva elaborados na região do Planalto Norte Catarinense na safra 2021. O presente estudo foi realizado no Instituto Federal de Santa Catarina – IFSC Câmpus Canoinhas, abrangendo a região do Planalto Norte Catarinense - Santa Catarina. As avaliações foram realizadas em triplicata, sendo avaliados as variáveis: densidade relativa (g mL-1), sólidos solúveis (°Brix), Grau Glucométrico (°Babo), acidez titulável total (meq L-1) e pH. Observou-se para as dez amostras avaliadas, valores médios de densidade relativa de 1,0476 g mL-1. Para o teor de sólidos solúveis (°Brix) observou-se valor médio de 11,79° Brix. O grau glucométrico, expresso em °Babo, apresentou entre as amostras avaliadas valor médio de 9,82 °Babo, com valores variando de 7,0 a 15,0 °Babo. O valor médio para a variável acidez total titulável foi de 75,6 meq L-1, com valores entre 63,0 a 89,2 meq L-1. Observou-se valor médio de 3,32 para o pH das amostras, com valores variando de 3,2 a 3,62. O Planalto Norte Catarinense possui potencial para a elaboração de sucos de uva de qualidade, contudo, é importante atentar-se ao ponto de maturação das uvas colhidas, com intuito de obter produtos com maiores teores de sólidos solúveis, grau glucométrico e densidade relativa, além da necessidade de refinar o processo de elaboração.
Preparation and evaluation of a liquid fertilizer from lactic fermentation of weeds
Authors: Dominguez Elizabeth Bereníce Chihuan , Morales Juan Gabriel Juscamaita , Tejada Jorge Luis , Ticllahuanaco Edgar Huamani
Published: December 2023

A total of twenty mixtures of weed, B-Lac and molasses were prepared in order to evaluate an accelerated liquid fertilizer (ALF) based on these plants. A mixture of 85% weed: water (1:1), 10% molasses and 5% B-Lac showed the best characteristics and was reproduced at a pilot scale. ALF was applied to lettuce using the following treatments: one foliar application per week of 10 mL L-1 (FA1), two foliar applications per week of 10 mL L-1 (FA2), one drench application of 50 mL L-1 every week (DA1), a drench application of 50 mL L-1 every two weeks (DA2) and a control without application (CWA). The variables evaluated were total yield, commercial yield, fresh weight, height, head diameter, percentage of dry matter and the concentration of foliar nitrogen, phosphorus, and potassium. The mixtures in the laboratory and pilot phase were evaluated in a completely randomized design. The field phase was assessed in a completely randomized block design with five treatments and four replications. No significant differences were found between the treatments, except in the percentage of dry matter and potassium content, where FA2 showed the best results (2.35% and 541 mg plant-1, respectively). The highest total yield (26.4 t ha-1) and commercial (24.11 t ha-1) were achieved with DA2; however, the nutritional content was lower than that in the other treatments. Using homolactic fermentation it was possible to recycle weeds and produce ALF, which has potential as a biofertilizer according to its chemical characterization and effects shown on lettuce cultivation.
Coupled nucleation of dual-phase lamellar structure
Authors: Zheng Gong , Chen Yang , Xiang Henggao , Zhang Jinpeng , Tu K. N. , Feng Chenming , Li Pei , Song Lin , Sha Gang , Qi Zhixiang , Chen Guang
Published: December 2023

Although lamellar structures widely exist in materials, the existing nucleation knowledge has failed to describe the nucleation process of lamellae. This is because it involves the simultaneous formation of two different phases whose early-stage nuclei are always anisotropic and ordered. We report here a coupled nucleation of lamellae in a eutectoid TiAl system, demonstrating the coupled formation of a pair of anisotropic and ordered α2 + γ lamellae from the matrix, and each pair nucleates independently and heterogeneously. The coupled pair has been identified by alternative segregation of Nb in the interface using atom probe tomography. The nucleation kinetics have been confirmed by atomistic simulations and in situ high-energy synchrotron X-ray diffraction. A theoretical model has been proposed for this heterogeneously coupled nucleation, offering potential applications in various systems or phase transitions involving anisotropic, ordered, or lamellar structures. This coupled nucleation model represents a significant enhancement to the existing nucleation theory.
Farmed Fish Market in Svay Rieng Town, Svay Rieng Province
Authors: Mardy Serey  , Chhun Hong  , Chanthorn Thoeung  , Chanthona Prak  , Leat Phai
Published: December 2023

The fisheries sector in Cambodia plays an important role in the economic, security, food, and nutrition sectors, including freshwater, seawater, and aquaculture. This study aims to 1) understand the type and size of farmed fish in Svay Rieng town, 2) understand the farmed fish market chain in Svay Rieng town, and 3) analyze the economic efficiency of selling farmed fish in Svay Rieng town. As a method, a survey was conducted by selecting 40 samples (fish vendors) from Veal Yun Market and Rong Bonler Market in Svay Rieng town by face-to-face interviewing. The results found that the activities of selling and consumption of farmed fish in the market are very active. Fish vendors sold many types of farmed fish. The fish types that the vendors sell the most are channa striata, clarias macrocephalus, channa micropeltes, red tilapia, pantius gorionothus, puntioplites, and other types. The fish market chain in Svay Rieng town is traded and trafficked from brokers to traders and fish vendors in the market and resold to wholesalers, retailers, and consumers. For the economic efficiency analysis of farmed fish sales in Svay Rieng town, there is a majority of vendors who are prosperous. To encourage local fish farming, the government should step up its efforts to support farmers who raise fish as a family and those who depend on fishing for their livelihood by educating and training them to cut back on imports.
Multiple Myeloma, Version 2.2024, NCCN Clinical Practice Guidelines in Oncology
Authors: Kumar Shaji K. , Callander Natalie S. , Adekola Kehinde , Anderson Larry D. , Baljevic Muhamed , Baz Rachid , Campagnaro Erica , Castillo Jorge J. , Costello Caitlin , D’Angelo Christopher , Devarakonda Srinivas , Elsedawy Noura , Garfall Alfred , Godby Kelly , Hillengass Jens , Holmberg Leona , Htut Myo , Huff Carol Ann , Hultcrantz Malin , Kang Yubin , Larson Sarah , Lee Hans C. , Liedtke Michaela , Martin Thomas , Omel James , Robinson Timothy , Rosenberg Aaron , Sborov Douglas , Schroeder Mark A. , Sherbenou Daniel , Suvannasankha Attaya , Valent Jason , Varshavsky-Yanovsky Asya Nina , Kumar Rashmi , Snedeker Jenna
Published: December 2023

The treatment of relapsed/refractory multiple myeloma (MM) has evolved to include several new options. These include new combinations with second generation proteasome inhibitors (PI); second generation immunomodulators, monoclonal antibodies, CAR T cells, bispecific antibodies, selinexor, venetoclax, and many others. Most patients with MM undergo several cycles of remissions and relapse, and therefore need multiple lines of combination therapies. Selecting treatment options for relapsed/refractory MM requires consideration of resistance status to specific classes, and patient-specific factors such as age and other comorbidities should be considered. The NCCN Guidelines for MM provide a framework on which to base decisions regarding workup, treatment, and follow-up of newly diagnosed and previously treated MM. This manuscript outlines the recommendations from NCCN Guidelines for MM specific to relapsed/refractory disease.
Determinación de la contribución de valor de filgotinib para el tratamiento de la colitis ulcerosa de moderada a grave mediante el análisis de decisión multicriterio (MCDA)
Authors: Taxonera Carlos , Sala Ferran , Martín Isabel , Nazco Júlia , Marín Laura , Nos Pilar , Amián Raúl , Arocas Vicente , Martín Arancha , Blasco Martí , Subirán Rafael
Published: December 2023

Objetivo: El objetivo de este estudio fue determinar la contribución de valor de filgotinib en el tratamiento de la colitis ulcerosa de moderada a grave en España, comparado con sus principales alternativas terapéuticas.
Metodología: Se seleccionó el marco EVIDEM para el análisis de decisión multicriterio (MCDA). El marco EVIDEM está formado por 12 criterios cuantitativos y 4 criterios contextuales. Se llevó a cabo una revisión de la literatura para poblar el marco con evidencia relevante para cada criterio. Un panel multidisciplinar formado por 8 expertos determinó la contribución de valor de filgotinib comparado con vedolizumab, ustekinumab, tofacitinib y upadacitinib. Se calcularon las medias, medianas y desviaciones estándar (DE) para los criterios cuantitativos. Los criterios cualitativos se analizaron según porcentaje de expertos que consideraron un impacto positivo, neutral o negativo para el Sistema Nacional de Salud. Se calculó la contribución de valor global de filgotinib.
Resultados: La colitis ulcerosa se consideró una enfermedad moderadamente grave (media ± DE: 3,4±0,7), con una población afectada reducida (2,4±0,5) en comparación con otras enfermedades inmunomediadas, y con necesidades no cubiertas moderadas (3,0±0,9). Los expertos percibieron que filgotinib puede aportar un beneficio similar a sus comparadores en eficacia/efectividad (-0,1±0,8) y seguridad/tolerabilidad (0,0±1). Se observó un pequeño beneficio en los resultados percibidos por los pacientes (0,8±1,3). Los expertos acordaron que de manera global filgotinib aporta un beneficio terapéutico moderado (2,9±0,6). Los expertos anticiparon un menor coste del tratamiento (2,6±0,9), un impacto bajo o nulo en otros costes médicos (0,5±0,9) y otros costes no-médicos/indirectos (0,4±0,7). La evidencia presentada por filgotinib se consideró robusta (3,6±0,9), con alto consenso sobre su futura recomendación en las guías clínicas en España (3,1±0,6). En los criterios contextuales, la mayoría de los expertos percibieron un impacto positivo en las prioridades de acceso de la población (88%), objetivo común e intereses específicos (75%), capacidad del sistema y uso adecuado (71%) y costes de oportunidad y asequibilidad (100%). El resultado de la contribución de valor global de filgotinib fue de 0,4 (en una escala de -1 a +1).
Conclusión: Filgotinib aporta valor añadido al manejo de la colitis ulcerosa de moderada a grave, mostrando un buen balance beneficio/riesgo y mostrando un impacto potencialmente positivo en los costes de tratamiento y en la conveniencia para el paciente.
Palabras clave: Colitis ulcerosa, inhibidores JAK, Análisis de decisión multicriterio, MCDA, toma de decisiones, evaluación medicamentos.
BENDA E ARBRIT NË MESJETËN E VONË
Authors: Xhufi Pëllumb
Published: December 2023

Në fund të shek. XII, në mënyrë të qartë, por në fakt qysh në shek. XI, në burimet bizantine dhe në ato papale e sllave, përmendet vazhdimisht krahina e Arbrit . Këtu u krijua i pari formacion shtetëror mesjetar shqiptar, Principata e Arbrit. Për vetë pozicionin gjeografik, afër Durrësit e përgjatë rrugës Egnatia, Arbri ka qenë në qendër të historisë mesjetare jo vetëm shqiptare, por edhe të asaj adriatiko-ballkanike, dhe jo më kot, balkanologë e albanologë të shquar, e kanë pagëzuar Arbrin si “bërthamën” e Shqipërisë Mesjetare.
AN OVERVIEW OF THE NUTRITIONAL STATUS OF CHILDREN AGED 6 - 60 MONTHS AT "KHANZA DAYCARE"
Authors: Jannah Jauharotul
Published: December 2023

Background: Nutritional problems are one of the most common health problems, especially among children in the world. Malnutrition will cause stunted growth and development of children. Nutritional status is the sensitive indicator of a child's health, and under-five children constitute the most vulnerable segment of any community. Adequate nutrition is a necessary first step in the improvement of quality of life. Nutrition plays a key role in the physical, mental, and emotional development of children, and much emphasis has been given to provide good nutrition to growing populations, especially in the formative years of life.
Aims: To overview of the nutritional status of children aged 6 60 months at Khanza Daycare.
Methods: This type of research is descriptive research with a cross sectional approach. Sampling was carried out using total sampling technique. The research population was children aged 6 36 months with a sample size of 12 children.
Results: The research results showed that the child had a normal weight of 100. Short children 16.7, normal 83.3. Children with over nutrition are 8.3 and normal nutrition are 91.7. Children at risk of overnutrition are 8.3, overnutrition 8.3, and normal 83.4.
Conclusion: Based on the research results obtained, the nutritional status of children aged 6 - 60 months at Khanza Daycare has a good nutritional level, so working mothers do not need to worry about entrusting their children to the daycare.