bluuebunny/crossref_metadata_2025 huggingface dataset:
Influence of contact network voltage fluctuations on current transients in the electric locomotive power circuit
Authors:   Ural state university of railway transport (USURT), Kuznetsov A. I.
Published: July 2022

The statistics of electric arc transfers along the collector of traction electric motors of the 2ES6 electric locomotive for 2020 are given. It is noted that half of the failures are associated with a potential spark on the collector, which indicates increased armature currents in the electric locomotive power circuit. The given voltage curve of the contact network also indicates that the power circuit is subject to constant current fluctuations. In the model of the power circuit of the 2ES6 electric locomotive, the mechanical component of the drive has been modified. It takes into account the resistance to train movement on one of the difficult sections of the Sverdlovsk Sabik - Sarga railway, as well as the inertia of the rotating parts of the 2ES6 electric locomotive and four-axle freight gondolas. The effect of voltage fluctuations in the contact network on current transients at different values of the maximum excitation voltage has been modelled. It is established that with the increase in the excitation voltage, the amplitudes of the armature current and the excitation current decrease, the duration of exceeding the currents of their limit value decreases. With voltage fluctuations up to 200 V, the armature current and the excitation current in the power circuit of the 2ES6 electric locomotive are in the range of their limit values with the increased value of the maximum excitation voltage of 120 V. With voltage fluctuations of more than 200 V, it is advisable to use low pass input filters.
Volterra integral equation method in the study of dynamics of self-gravitating gas bounded by free surface
Authors:   Ural state university of railway transport (USURT), Chuyev N. P.
Published: July 2022

The paper investigates dynamics of the finite mass of self-gravitating ideal gas with a variable flow bounded by free surface. Unsteady gas flows are described by a phenomenological mathematical model of gas dynamics, which is constructed using a system of nonlinear integral-differential equations written in Eulerian coordinates. The gas motion is considered under the condition that the free boundary at all times consists of the same particles. This circumstance makes it convenient to switch from Eulerian coordinates to Lagrangian coordinates, for which the domain of determining the solution of the gas motion problem will be fixed in advance. The transformation of the system to Lagrangian coordinates makes it possible to reduce it to an equivalent system consisting of Volterra-type integral equations and the continuity equation in Lagrangian form, and get rid of the unknown boundary. Using the method of successive approximations, properties of compact spaces, a series of original and specific estimates found for functions describing the flows of the self-gravitating gas, convergence of a sequence of approximate solutions is proved under assumptions about smoothness of the initial data. The theorem of existence and uniqueness of the solution of the Cauchy problem for the system of integral equations of the Volterra type is proved, and, consequently, the solution of the desired problem is found within the framework of the assumptions made about the motion in vacuum of the isolated mass of the self-gravitating ideal gas with a variable flow domain.
Improving the reliability of batteries on electric trains
Authors:   Ural state university of railway transport (USURT), Buynosov A. P. , Kozlova A. A. ,   Ural state university of railway transport (USURT)
Published: July 2022

The issue of improving reliability of some components and parts of electric trains to reduce the number of unscheduled repairs, which contributes to improving the organization of maintenance of electric trains, is under study. The issues of violations in operation of technical means of electric trains are considered, the most unreliable components and parts that negatively affect the operation of motor-car rolling stock as a whole are identified. The main causes of premature failures of batteries as one of the most unreliable devices on electric trains have been established. The design, the principle of operation of the battery, its functions are given, the reasons for the premature failure of this unit are considered. As a method of increasing reliability of batteries, the authors propose the use of a device that can increase reliability of this node by eliminating the main causes of failures, explains the scheme and principle of operation of the proposed device, reveals the features of its operation. Special attention is paid to the adjustment characteristics of the proposed unit, its main functions and advantages in its use are revealed. It was found that with the increase in reliability of batteries, the number of unforeseen failures that contributed to the unplanned repair of electric trains is significantly reduced.
Working diagnostics of thyristor arms of a rectifier-inverter converter of an ac electric locomotive
Authors:   Far Eastern State University of Railway Transport, Skorik V. G. , Buneyeva E. V. ,   Far Eastern State University of Railway Transport, Suprun D. A. ,   Far Eastern State University of Railway Transport
Published: July 2022

The article considers the principle of working diagnostics in real time of a rectifier-inverter converter of an AC electric locomotive in case of shoulder control failure. The proposed principle is based on the harmonic analysis of the rectified voltage curve and identification of the relative content of individual harmonics that are missing in normal mode. To increase reliability of detection of the damaged shoulders, it is proposed to use a diagnostic criterion based on assessment of changes in the resulting energy output of the converter at certain intervals of the mains voltage period. Due to the joint application of several criteria, damage detection with the necessary level of sensitivity is achieved. For each criterion, two groups of boundary values are calculated, due to which the selectivity of determining the failed shoulder is realized. The justification of the selected boundary conditions that distinguish the emergency mode from the normal one is presented. A simulation model has been created in the MatLAB Simulink software package, which allows exploring the possibilities of diagnosing a rectifier-inverter converter for various operating conditions. The results of simulation modeling confirming correctness of the proposed solutions are presented. It is indicated that the proposed diagnostic method should be used together with the alternative converter control algorithm that ensures operability of the electric part of the electric locomotive in case of failure of one of the arms.
Formation of a system of transport hubs in conditions of changing passenger traffic
Authors:   Samara State University of Railway Transport, Moskvichev O. V. , Leonova S. A. ,   Samara State University of Railway Transport
Published: July 2022

The paper proposes a quantitative method for determining the optimal location of transport interchange hubs (TH), based on identification of effective transfer hubs, which allows predicting the location of the TH system with sufficient accuracy according to the criterion of reducing the average duration of trips around the city. The method is based on the heuristic algorithm that allows you to determine the optimal direct and transfer routes (with one, two or more transfers) and identify effective transfer nodes. In such nodes, the TH should be created. The method was tested on the example of the Samara city public transport system. The TH system is proposed, which allows to reduce the average travel time on the urban transport network by reducing the time of transfer trips. Regardless of the size of passenger traffic, the maximum reduction in the average duration of a trip in Samara due to the creation of a TH system is six minutes. The fluctuation of passenger traffic and its influence on the choice of TH is investigated. The dependence of the number of TH, the construction of which makes it possible to achieve marginal reduction in the average duration of a trip around the city due to the formation of TH system on passenger traffic is obtained.
Formation of professional subjective activity of future teachers in the field of upbringing
Authors:   Novosibirsk state pedagogical university, Novosibirsk, Abramova Viktoriya V. , Romm Tatyana A. ,   Novosibirsk state pedagogical university, Novosibirsk
Published: July 2022

The increased attention of the state and society to education as an integral part of the educational process at all levels of education actualizes the problem of the readiness of future teachers to implement educational tasks. To determine the prospects of this activity, the provisions of the modern theory of education have a significant place, which is the methodological basis for considering the role and place of the teacher and his subjectivity in the process of preparing for educational activities. In order to achieve a high degree of readiness for professional activity, it is necessary to have a certain personal, intellectual and activity potential, which means that personal and professional changes are an integral attribute of the development of professionally significant personality traits that should be included in the logic of the organization of the process of professional education in the academic and extracurricular components. The success of the educational activity of a novice teacher in the future largely depends on the student's activity in professional self-development during the period of study at the university. The readiness of teachers for educational activities is largely determined by the formation of professional subjective activity of the individual. Professional subjective activity is considered as the activity of a personality that develops and implements its subjectivity in the space of professional activity. Its main characteristics are uniqueness, activity, independence, responsibility, authorship of one's own life and one's own history, value relations, the ability to master one's own behavior and generate one's own behavior. For their formation, it is necessary to create special conditions in a pedagogical university: the organization of horizontal and vertical subjectsubject interaction; development of the mentoring system; development of the institute's life activity as a professional educational organization that creates a space for the accumulation of individual professional style and operational repertoire for solving professional tasks.
Socio-political aspects of reforming russian academic science
Authors:   Russian academy of sciences, Moscow, Naumova Tatyana V.
Published: July 2022

The article considers some areas of reform of academic science, namely a radical change in the existing form of academic scientific activity, the restructuring of domestic science according to Western models, in addition, some attention is paid to such a direction of reform as reduction in the number of research institutes and scientists working there. In this regard, on the basis of the analysis of important components of science, it is shown that academic science is now the most effective sector of science, the basis of the country's scientific potential. As for the policy of the state aimed at optimizing scientific activity, in other words, restructuring science, it negatively affects its development. The article gives an assessment of the reform results, it turns out its impact on the state of Russian science. In this regard, the level of Russian research in certain fields of science is assessed, the place of modern domestic science in world science is being investigated. The main focus is on the question of in which scientific fields Russian research is at the level of development of world science or ahead of it, and where – to one degree or another lag behind it. Particular attention is paid to the consideration of measures to accelerate the development of fundamental science in our country. In this regard, the problems of increasing research funding, eliminating state interference in the process of self-organization of the academic scientific community, modernizing the infrastructure of academic science, ensuring the worthy position of the scientific elite, especially young scientists, whom the future of Russian science in the third millennium largely depends on, are analyzed.
Results of implementation of gaming technology as a pedagogical means of forming the organizational and managerial competence of a future manager
Authors:   Institute for education development, Zolotareva Angelina V. , Sarafanova Irina E. ,   Yaroslavl state pedagogical university named after К. D. Ushinsky
Published: July 2022

The article presents the results of a study of the implementation of gaming technology as a pedagogical means of forming the organizational and managerial competence of a future manager at a university. The essence of the “means of learning” concept is revealed; the relevance of the use of pedagogical means in the process of vocational education is substantiated; the degree of development of the problem of using games in the process of training and professional development of managerial personnel at the university is shown. The competence-based and contextual approaches are presented as the methodological basis of the study; the features of the application of the competence-based process for the organization of the formation of the organizational and managerial competence of the future manager are disclosed; the concept, essence, structure and tools for assessing the organizational and managerial competence of a future manager are disclosed; the possibility of using the contextual approach for the formation of organizational and managerial competence of a manager in activities, including in the process of playing activities as a way of learning is shown; the principles of the implementation of games aimed at the formation of this competence are described - subjectivity, problematicity, professional orientation, dialogue, joint activity of game participants. The article presents a set of games implemented in the research process and includes the following game technologies: business game “Goal-setting as a basis for planning”, simulation game “Effective Communications”, role-playing game “Delegation of Authority”, business game “Effective Control”, “Organization of planning”, “Organization of control”. To confirm the effectiveness of the introduction of gaming technologies in the process of training student managers at the university, the results obtained in the control and experimental groups are shown, the results of processing the results based on the Mann-Whitney U-criterion are given; conclusions are drawn that the use of gaming technologies has proven its effectiveness.
Chirality in the Solid State: Chiral Crystal Structures in Chiral and Achiral Space Groups
Authors: Fecher Gerhard H. , Kübler Jürgen , Felser Claudia
Published: July 2022

Chirality depends on particular symmetries. For crystal structures it describes the absence of mirror planes and inversion centers, and in addition to translations, only rotations are allowed as symmetry elements. However, chiral space groups have additional restrictions on the allowed screw rotations as a symmetry element, because they always appear in enantiomorphous pairs. This study classifies and distinguishes the chiral structures and space groups. The chirality is quantified using Hausdorff distances and continuous chirality measures and selected crystal structures are reported. The chirality is discussed for bulk solids and their surfaces. Moreover, the band structure, and thus, the density of states, is found to be affected by the same crystal parameters as the chirality. However, it is independent of handedness. The Berry curvature, as a topological measure of the electronic structure, depends on the handedness, but is not a proof for the chirality because it responds on the inversion of a structure. For molecules, optical circular dichroism is one of the most important measures for the chirality. Thus, it is proposed in this study that the circular dichroism in the angular distribution of photoelectrons in high symmetry configurations can be used to distinguish the handedness of chiral solids and their surfaces.
Distribution, Assessment, and Source of Heavy Metals in Sediments of the Qinjiang River, China
Authors: Zhang Shuncun , Chen Bo , Du Junru , Wang Tao , Shi Haixin , Wang Feng
Published: July 2022

Heavy metals are toxic, persistent and non-degradable. After sedimentation and adsorption, they accumulate in water sediments. The aim of this study was to understand the heavy metal pollution of Qinjiang River sediments on the ecological environment and apportioning sources. The mean total concentrations of Mn, Zn, Cr, Cu, and Pb are 3.14, 2.33, 1.39, 5.79, and 1.33 times higher than the background values, respectively, except for the Co, Ni, and Cd, which are lower than the background values; Fe, Co, Ni, Cd, Cr, Cu, and Pb are all primarily in the residual state, while Mn and Zn are primarily in the acid-soluble and oxidizable states, respectively. Igeo, RI, SQGs and RAC together indicate that the pollution status and ecological risk of heavy metals in Qinjiang River sediments are generally moderate; among them, Fe, Co, Ni, Cd, Cr, and Pb are not harmful to the ecological environment of the Qinjiang River. Cu is not readily released because of its higher residual composition, depicting that Cu is less harmful to the ecological environment. Mn and Zn, as the primary pollution factors of the Qinjiang River, are harmful to the ecological environment. This heavy metal pollution in surface sediments of the Qinjiang River primarily comes from manganese and zinc ore mining. Manganese carbonate and its weathered secondary manganese oxide are frequently associated with a significant amount of residual copper and Cd, as a higher pH is suitable for the deposition and enrichment of these heavy metals. Lead-zinc ore and its weathering products form organic compounds with residual Fe, Co, Cr, and Ni, and their content is related to salinity. The risk assessment results of heavy metals in sediments provide an important theoretical basis for the prevention and control of heavy metal pollution in Qinjiang River.
The Geometry of Thermodynamics III
Authors: Velazquez Luisberis , Parker Michael Charles , Jeynes Chris
Published: July 2022

We survey the main results emerging in the rapidly developing field that considers the
geometry of thermodynamics and statistical mechanics. Our ideas of stability depend on variational
principles – Maximum Entropy together with Least Action (and the isomorphic Least Exertion) – and
this stability (invariance in time) indicates the centrality of the geometries of the systems. We explore
a variety of examples of the application of thermodynamics in both macro- and micro-systems,
and propose that irreversibility is an intrinsic and fundamental property of the physical realm
(instead of being merely emergent). Using the concept of complex time, we examine the underlying
mathematical unity of quantum mechanics, statistical mechanics, and geometrical thermodynamics.
We show how the Planck and Boltzmann constants provide the fundamental quantum units for
the phenomenological characteristics of the two Noether-conserved quantities controlling overall
thermodynamic behaviour: respectively, energy and entropy production. We discuss the far-reaching
isomorphisms (between all of complex time, temperature and the system symmetry) that always
exist for Maximum Entropy systems, even as they exhibit either irreversible (dissipative, yet still
dynamically stable) or reversible (including stable and static geometries) behaviours.
Absorptive Capacity, Strategic Flexibility, Bricolage, and Product Innovation: Empirical Evidence from Chinese SMEs
Authors: Kuankuan Luo , Zhang Liming
Published: July 2022

There have been relatively few researches that determine the role of bricolage in mediating the empirical relationship between strategic flexibility and product innovation. However, most of the research has studied strategic flexibility to engage the absorptive capacity and facilitate product innovation. The Bricolage approach emphasizes utilizing existing resources in product innovation and explores the mechanisms behind bricolage. A resource-based approach to product innovation involves combining resources in the development process in a concrete manner. This is a groundbreaking study since it is the first to examine empirically how absorptive capacity affects product innovation through bricolage and the serial mediation of strategic flexibility. As a consequence of presenting our results, we concluded that absorptive capacity positively and significantly influences product innovation through the serial mediation of strategic flexibility and bricolage. For strategic flexibility to play a role in supporting product innovation, bricolage is one of the mechanisms that can be utilized. This study contributes to the literature on strategic flexibility by examining the effect of strategic flexibility on bricolage and product innovation from the standpoint that absorptive capacity enhances the strategic flexibility of high-tech SMEs in China. Furthermore, this research offers new insights into the relationship between absorptive capacity and product innovation. In addition, it also provides insight into the economic opportunities that may result from product innovation in transition economies such as China.
Smart and Sustainable Management of Shoes Machinery Company in Taiwan during the Covid-19 Pandemic－Case Studies of the Tung Sheng Company and Strong Basic Enterprise Limited Company
Authors: Tu Ming-Ta , Gau Li-Shiue , Park Ji-Hwan , Huang Wen-Shin , Duong Pham Thuy , Kim Jong-Chae
Published: July 2022

During the Covid-19 pandemic in Taiwan, analytical tools of PEST (political, economic, social-cultural, and technological), SWOT (strength, weakness, opportunity, threat), nine building blocks of a business model canvas, and knowledge management were combined to develop a theoretical framework, and used to assess business, smart and sustainable management of two case companies: Tung Sheng Company Limited and its subsidiary, Strong Basic Enterprise Limited. A heuristic inquiry research design was adopted. In addition to secondary data from the two case companies, major top managers were interviewed to reveal constructive questions about the existing business models and to re-interpret strategy. The results showed that case companies own capabilities of R & D (research and development) as a foundation to further apply new smart ICT (information and communication technology) and execute green manufacturing. Additionally, strong key partnerships are used to diversify business investment for leveraging on limited resources given current insufficient qualified employees. Resilient practices adopted new and green technology to help mitigate the negative impacts of the Covid-19 pandemic. This study provides a useful framework and practical information about how to examine business models, smart and sustainable management processes of the two case companies and to make adjustments in strategies for the future.
Advances in Digital Transformation: a Historical Review in Times of COVID
Authors: Reyes-Cornejo Pablo , Uribe-Bahamonde Yerco E. , Boada-Grau Joan , Araya-Castillo Luis
Published: July 2022

The new SARS-CoV-2 coronavirus has brought with it an increase in the use of digital platforms and an exponential increase in the number of scientific papers worldwide. The purpose of this study is to show a global overview of the digital transformation from 1975 to the present (2021). The main collection of the Web of Science database was used to retrieve global scientific production on digital transformation. Bibliometric indicators of production, visibility, impact, and collaboration were analyzed to assess research progress on the topic. The results show that digital transformation is a construct of recent development, increasingly relevant and transdisciplinary, with a clear growth after the declaration of the global COVID-19 pandemic.
A Method to Study Extracorporeal Development of Early Planococcus Citri Embryos: a New Schedule for Facultative Heterochromatinization
Authors: Posukh Olga , Osipov Yakov , Kalashnikova Darya , Antoshina Polina , Belyakin Stepan , Singh Prim
Published: July 2022

Study of imprinted heterochromatinization of the paternal chromosome set in male mealy bugs is made difficult because it takes place at the blastula stage within the ovary. We describe here a method that allows for the bulk preparation of staged early embryos that develop normally outside the mother. We define an accessible experimental window encompassing 48 to 72hours post-mating in which regulation of heterochromatinization of the paternal chromosome set can now be investigated outside the confines of the ovary.
An Account of Models of Molecular Circuits for Associative Learning with Reinforcement Effect and Forced Dissociation
Authors: Li Zonglun , Fattah Alya , Timashev Peter , Zaikin Alexey
Published: July 2022

The development of synthetic biology has enabled us to make massive progress on biotechnology and to approach research questions from a brand new perspective. In particular, the design and study of gene regulatory networks in vitro, in vivo and in silico, have played an increasingly indispensable role in understanding and controlling biological phenomena. Among them, it is of great interest to understand how associative learning is formed at the molecular circuit level. Noticeably, mathematical models have been increasingly used to predict the behaviors of molecular circuits. The Fernando’s model, which is thought to be one of the first works in this line of research using the Hill equation, attempted to design a synthetic circuit that mimics Hebbian learning in the neural network architecture. In this article, we carry out in-depth computational analysis of the model and demonstrate that the reinforcement effect can be achieved by choosing the proper parameter values. We also construct a novel circuit that can demonstrate forced dissociation, which was not observed in the Fernando’s model. Our work can be readily used as reference for synthetic biologists who consider implementing the circuits of this kind in biological systems.
Detection of Antibodies in Patients with Sarcoidosis
Authors: Starshinova Anna , Malkova Anna , Zinchenko Ulia , Lapin Sergey , Mazing Alexandra , Kudlay Dmitry , Yablonskiy Piotr , Shoenfeld Yehuda
Published: July 2022

There is a need to further characterize the antibody response to vimentin in relation to it possible involvement in pathogenicity of sarcoidosis, and other lung disorders. Objectives: We investigated serum samples from patients with sarcoidosis, healthy and diseased control subjects to evaluate levels and frequency of these antibodies. Materials and methods. A retrospective-prospective comparative study was performed in the years 2014-2017. 188 serum samples were examined for presence of autoantibodies to mutated citrullinated vimentin (anti-MCV). Patients with elevated anti-MCV levels were tested for antibodies to a cyclic citrullinated peptide (anti-CCP) and citrullinated vimentin (anti-Sa). Additionally, sera from 93 patients with sarcoidosis and 40 healthy subjects were evaluated for the presence of autoantibodies to non-modified vimentin. In all cases ELISA assays was used. The results were considered statistically significant at p-value less than 0.05. Results of the study. The high concentrations of anti-MCV. antibodies were more frequent in patients with sarcoidosis (40.9% of the cases, 38/93), compared to the control groups (23.6% and 25.0% of cases, respectively). In sarcoidosis, clinical symptoms similar to the autoimmune pathology were described. A moderate positive correlation between the anti-MCV and anti-Sa antibodies (r = 0.66) was found in 13 patients with sarcoidosis. There was no significant difference between the levels of the anti-MCV and the anti-CCP in patients with non-infectious lung diseases and the healthy control group. Conclusion. A high level of anti-MCV antibodies in patients with sarcoidosis characterizes the presence of an autoimmune process that is not related to citrullination. The absence of a significant difference in the level of antibodies to modifications of vimentin in patients with sarcoidosis may indicate the autoimmune process.
MHD_NX: ideal MHD stability code on two-dimensional unstructured grids
Authors: Medvedev Sergei Yur’evich , Martynov Alexander Alexandrovich , Poshekhonov Yuri Yurievich
Published: July 2022

The code developed by the authors for calculating the MHD stability of two-dimensional plasma configurations with an arbitrary magnetic field topology is presented. The choice of an appropriate version of the finite element method on hybrid unstructured computational grids and test calculations are discussed. Examples of using the code for modeling the plasma stability in Galatea traps and in divertor configurations of tokamak taking into account the plasma beyond the separatrix are given.
Clinically Significant Drug Interactions for Direct Oral Anticoagulants: State of the Art
Authors: Gilyarevsky S. R.
Published: July 2022

The article is devoted to modern ideas about the role of drug interactions as a factor affecting the efficacy and safety of the use of direct oral anticoagulants (DOACs) in clinical practice. Data on drug interactions of apixaban, rivaroxaban and dabigatran with the drugs most frequently used in patients with cardiovascular diseases are given. Drug interactions for DOACs, depending on concomitant use of drugs that are inhibitors or inducers of the CYP3A4 enzyme or P-glycoprotein enzymes, are determined by most of the drug interactions of DOACs are considered. The results of studies in which drug interactions of DOACs were assessed by changes in indicators such as the area under the concentration-time curve and the maximum or minimum concentration of drugs in the blood are discussed. The data presented in the article may be useful for accounting for drug interactions in the treatment of patients with DOACs in clinical practice, despite the current lack of reasonable dose adjustment rules depending on the majority of such interactions. The data presented in the article suggest that apixaban has the fewest number of clinically significant interactions among the DOACs available in Russia.
The Effect of Enhanced External Counterpulsation on the Vascular State, Indicators of Glycemic Control and Quality of Life in Patients with Coronary Artery Disease and Type 2 Diabetes Mellitus
Authors: Slepova O. A. , Lishuta A. S. , Vasiltsova E. Yu. , Privalova E. V. , Belenkov Yu. N.
Published: July 2022

Aim. To study the effect of enhanced external counterpulsation (EECP) on the functional status, quality of life, structural and functional state of the vascular bed, and markers of glycemic control in patients with coronary artery disease (CAD) and type 2 diabetes mellitus (DM).

Material and methods. A pilot prospective randomized study included 30 patients with CAD and DM. Using a random number generator, patients were randomized into 2 groups: EECP (n=15) and a comparison group (n=15). All patients (n=30) received optimal medical therapy (OMT) during 3 months of follow-up. Patients in the EECP group underwent a course of EECP (35 hours, cuff pressure: 220-280 mmHg) during the first 7 weeks of the study. At baseline and after 3 months of follow-up, patients in both groups underwent an assessment of clinical status, quality of life (based on the SF-36 questionnaire), as well as a 6-minute walk test to assess exercise tolerance. The dynamics of fasting glucose, postprandial glucose, insulin resistance index (HOMA-IR) and glycated hemoglobin were assessed. Photoplethysmography and applanation tonometry were performed to assess the state of the vascular bed.

Results. In the EECP group, after 3 months, there was a decrease in the frequency of angina attacks and an improvement in the functional class of angina according to the Canadian Cardiovascular Society (CCS) classification. A significant improvement in exercise tolerance was revealed [an increase in the 6-minute walking distance by 51 (35; 65) m, p<0.05], as well as an improvement in the physical and mental components of health according to the SF-36 questionnaire. A positive dynamics was shown in relation to the indicators of the state of both large vessels and the microvasculature (p>0.05), with the exception of the reflection index and the stiffness index (p<0.05). There was also a significant decrease in the HOMA-IR [-9.9% (-26.5; -4.0) vs 7.7% (-7.9; 13.8), p=0.004], as well as in the levels of fasting glucose [-10.5% (-15.8; -4.0) vs -2.7 (-8.3; 5.9), p=0.012] in the EECP group, compared with the OMT group.

Conclusion. EECP course therapy in addition to OMT has a positive effect on the functional status and quality of life of patients with CAD and DM. After 3 months of observation, there was noted a positive dynamics of the vascular state, as well as markers of glycemic control, and these changes were more pronounced in the EECP group. The results obtained may indicate the effectiveness of EECP as an add-on treatment for this group of patients.
Historical Aspects of the Use of Antiarrhythmic Drugs in Clinical Practice
Authors: Doshchitsin V. L. , Tarzimanova A. I.
Published: July 2022

Heart rhythm disorders are one of the most urgent problems in cardiology. The first reports on the possibility of using drugs in the treatment of cardiac arrhythmias began to appear in the scientific literature from the middle of the 18th century. This pharmacotherapeutic direction has been developed since the second half of the 20th century, when new antiarrhythmic drugs began to be used in clinical practice. The introduction of new drugs and modern methods of treating arrhythmias into clinical practice has significantly improved the prognosis and quality of life of patients. Combination antiarrhythmic therapy, including antiarrhythmic drugs and radiofrequency ablation, seems to be the most promising and successful tactic for treating patients in the future. A historical review of the literature on the clinical use of antiarrhythmic drugs both in past years and at present is presented in the article.
Physicochemical Parameters of Ultrabasic Magmatic Systems of the Northeastern Siberian Platform (Data on Melt Inclusions in Chromian Spinel)
Authors: Simonov V.A. , Vasil’ev Yu.R. , Kotlyarov A.V. , Nikolenko E.I. , Alifirova T.A. , Sharygin V.V. , Aulbach S.
Published: July 2022

—Experimental studies and analysis of silicate inclusions testify to the magmatic genesis of part of chromian spinel from the Triassic deposits of the northeastern Siberian Platform. The compositions of melt inclusions in the chromian spinel show the participation of alkaline (potassic) magmas in their crystallization. Most data indicate the presence of magmatic systems similar to melts in the Guli ultrabasic massif in the northern Siberian Platform. Studies of the distribution of trace and rare-earth elements in the melt inclusions show the existence of several magmatic systems. These are, first of all, magmas that formed Guli-type ultrabasic massifs and gave rise to meimechites and picrites in the Maimecha–Kotui province. There are also plume-related magmatic systems with kimberlites, lamprophyres, and/or other continental “hot spots”. The composition of the melt inclusions suggests the existence of several types of the primary sources of chromian spinel in the northeastern Siberian Platform, which confirms the earlier data on the heterogeneous composition of the deposits of the diamondiferous Carnian (Upper Triassic) Stage. Applying computer modeling with the well-known COMAGMAT, PETROLOG, and WinPLtb programs as well as the Ol–Sp geothermometers based on the melt inclusions in chromian spinel from the Triassic deposits of the northeastern Siberian Platform, we have determined the P–T conditions of crystallization of minerals in the igneous rocks being the sources of the examined chromites. The temperature of liquidus crystallization of chromian spinel is 1324–1275 ºC. The P–T conditions of formation of olivine and clinopyroxene inclusions in it are estimated at ca. 4.5–4.1 kbar, 1510–1150 ºC and 3.2–1.0 kbar, 1285–1200 ºC, respectively.
Metodologia para o Monitoramento da Rede Pública de Água e Esgoto no Âmbito Municipal, para Prevenção à Covid-19
Authors: Barroca de Almeida Neto Onofre , Silva Gustavo Vieira , Dhingra Shermila Peres , BAU Morgana
Published: July 2022

Mediante solicitação do Ministério Público do Estado de Minas Gerais (MPMG), a Prefeitura Municipal de Rio Pomba (PMRP), a Companhia de Saneamento de Minas Gerais (COPASA) e o Instituto Federal de Educação, Ciência e Tecnologia do Sudeste de Minas Gerais, campus Rio Pomba (IF Sudeste MG), em parceria, propuseram ações de monitoramento do esgoto e da água potável distribuída no município de Rio Pomba pelas diferentes instituições, para prevenção e mitigação da propagação da Covid-19. Na água potável foram analisados pH e Cloro Residual Livre (CRL) e no esgoto o método utilizado para o diagnóstico de covid-19 foi o RT-PCR em tempo real. Todos os resultados de pH atenderam às recomendações legais e no esgoto não foram encontrados traços para SARS-CoV-2 vírus da Covid-19. Orientações e medidas corretivas foram dadas e tomadas para adequação dos valores de CRL encontrados fora dos parâmetros legais. Estes resultados nortearam as ações preventivas e corretivas contra Covid-19 das instituições envolvidas, durante o período analisado. O trabalho conjunto e preventivo entre as diferentes instituições, MPMG, PMRP, COPASA e IF Sudeste MG, demostrou ser eficiente, norteador e benéfico a toda comunidade.
Projeto para um Braço Robótico de Baixo Custo Baseado em Open Source e Impressão 3D
Authors: Xavier Reck Miguel Alberto , Antonello Ricardo
Published: July 2022

A robotização industrial abrange diversos campos da tecnologia, como a identificação e a movimentação de objetos. Este artigo, no formato de relato de experiência, deriva de um projeto de extensão iniciado em 2018, cujo propósito foi a construção de um braço robótico de código open source através de Impressão 3D no campus do IFC Luzerna, equipamento este a ser utilizado em atividades pedagógicas e em iniciativas de pesquisa e extensão universitária. Os códigos para movimentação do braço robótico foram inteiramente desenvolvidos na linguagem Python. Segundo os pressupostos do projeto, futuramente a utilização do braço robótico poderá permitir a identificação e movimentação automática de objetos para auxiliar a mão de obra humana dentro da indústria. O principal objetivo deste texto é descrever o processo de construção e montagem do braço robótico no âmbito do IFC Luzerna.
Metodologia para uma Aprendizagem Significativa através do Recurso ao Brincar
Authors: Fraga de Jesus Ivana Regina , TAVARES PEREIRA Maurício , Kimieciki Domingos
Published: July 2022

O estudo apresenta reflexões de como o professor pode desenvolver uma aprendizagem significativa e sólida, utilizando o brincar como recurso com as crianças que atualmente apresentam grande capacidade cognitiva pois surpreendem com suas hipóteses e questionamentos. Nesse sentido o lúdico é apresentado como uma ferramenta indispensável para desafiar e despertar a curiosidade das crianças, utilizando-se dos brinquedos, jogos e brincadeiras para desenvolver o conhecimento e a aprendizagem. Destaca que alguns professores já utilizam esses recursos, no entanto nem sempre, de forma consciente e contextualizada. Sendo assim, este estudo bibliográfico, busca orientar o professor para práticas que estimulam a valorização do brincar no processo de ensino e aprendizagem significativa para as crianças, tanto na educação infantil como no ensino Fundamental I.
A Novel Solution for Network Flexibility Problem in Mobile Multi-hop Tunneling Networks
Authors: Preveze Barbaros
Published: July 2022

Since the network throughput performance is always limited by the currently available technology limits, there are too many number of attempts in the literature to improve the network throughput performance by modifications on the running routing algorithms on the third layer of OSI (open systems interconnection) reference model. Although application of the tunneling on IP networks provide reserved paths for the higher priority packet streams and succeeds in providing faster communication performances, it is also determined in the literature that, the greatest up to date problem of tunneling networks, the flexibility problem, causes the difficulty of keeping the delay at lowest levels in case of instantly changing network conditions when there are congestions or node failures on the network. In this work, an alternative high performance solution, considering the locations of the nodes in addition to their traffic loads, has been proposed for network flexibility problem of mobile multi-hop tunneling networks. And it is shown that, it is succeeded to carry the throughput of the highly loaded traffic network back to 48.6 Mbps from 36.9 Mbps by about 31.7% performance improvement for which we could have improved it from 36.9 Mbps up to 45.9 Mbps by 24.3% using the proposed ACN (Avoid Congested Node) algorithm in our previous work. As a result, we have succeeded in having about 7.4% more improvement on throughput performance with respect to previously proposed ACN algorithm.
Robust Automatic Speech Recognition System for Kannada Speech Sentences in the Presence of Noise
Authors: Swamy Mahadeva
Published: July 2022

An Automatic Speech Recognition system is developed for recognizing the continuous and spontaneous Kannada speech sentences. The language models and acoustic models are constructed using Kaldi toolkit. The speech corpus is developed with the native female and male Kannada speakers and is partioned into training set and testing set. The Performance of the proposed system is analysed and evaluated using the metric Word Error Rate (WER). The Wavelet Packets amalgamated with Mel filter banks are utilized to perform feature vector generation. The proposed hand crafted features perform better than the baseline features such as Perceptual Linear Prediction(PLP), Mel Frequency Cepstral Coefficients(MFCC) interms of Word Error Rate(WER) under both controlled and uncontrolled conditions.
Optimal@NRW - Optimised acute care of nursing home residents using an intersectoral telemedical cooperation network – study protocol for a stepped-wedge trial
Authors: Brücken David , Unterkofler Jenny , Pauge Sophie , Bienzeisler Jonas , Hübel Christian , Zechbauer Sebastian , Rossaint Rolf , Greiner Wolfgang , Aufenberg Birthe , Röhrig Rainer , Bollheimer Cornelius , Brokmann Jörg Christian
Published: July 2022

Background: Increasing life expectancy is associated with a growing number of people living in nursing homes, while the availability of outpatient medical care, especially from family doctors, is stagnating in this sector. Consequently, numerous and often avoidable, low-threshold hospitalizations of nursing home residents are observed. This results in unnecessary use of resources such as emergency services and emergency rooms as well as in potential health risks to the nursing home residents related to hospitalization. This study aims to improve this healthcare gap by implementing an intersectoral telemedicine approach.Methods: 25 nursing homes are participating and provided with telemedical equipment to perform teleconsultations. Additionally, an early warning system and a digital patient record system is implemented. Telephysicians based at RWTH Aachen University Hospital are ready to support the nursing homes around the clock if the family doctor or an emergency service practice is not available in time. Mobile non-physician practice assistants from the telemedicine centre can be dispatched to perform delegable medical activities. General practitioners and the medical emergency practices also have access to the telemedical infrastructure and the non-physician practice assistants.Discussion: Optimal@NRW adds a telemedicine component to standard care – combining elements of outpatient and inpatient health care as well as emergency service practices - to enable timely medical consultation for nursing home residents in case of the development of an acute medical condition. In addition to optimized medical care, the goal is to reduce unnecessary hospital admissions. The intersectoral approach allows for the appropriate use of resources to match the individually needed medical treatment.Trial registration: ClinicalTrials.gov Identifier: NCT04879537. Registered May 10, 2021, https://clinicaltrials.gov/ct2/show/NCT04879537
Making it work: the experiences of delivering a community mental health service during the COVID 19 pandemic
Authors: Burton Leanne , Wall Abbie , Perkins Elizabeth
Published: July 2022

Purpose: The aim of this study was to explore how Community Mental Health Teams (CMHT) staff responded to delivering a service in a crisis. Background: The pandemic forced rapid and innovative change to care delivery. Knowledge about staff experiences may contribute to different approaches to managing staff during future pandemics and could be used in the design and implementation of interventions to support frontline mental health staff working to deliver community services.Methods: A qualitative semi-structured interview approach was adopted. Twenty-one staff from a CMHT in the North West of England, UK were recruited and interviewed remotely. Interviews took place in June and July 2020, three months after the UK entered its first national lockdown.Results: Analysis identified the approaches used by staff, from senior leadership down to those on the frontline, to try to make the service work in difficult circumstances. At every level of the organization staff talked about the challenges and strategies arising from a desire to deliver a service during the pandemic. The data is discussed under four headings; ‘senior trust managers trying to make it work’, ‘individuals making it work’, ‘making it work as a team’; and ‘making it work through working at home’. Clear communication of messages proved key across all areas, to ensure that government guidelines were followed, and that contact with service users and care delivery was directed at keeping people safe.Conclusion: In this study it was clear that the initial response to the pandemic involved the imposition of boundaries on staff by the Trust senior leadership to ensure the most vulnerable service users received a service while staff were kept safe. The data raises questions about how these boundaries were determined and whether the same outcome could have been achieved through involving staff more in the making of decisions about the delivery of services.