bluuebunny/crossref_metadata_2025 huggingface dataset:
IDENTIFICAÇÃO DE BIOMARCADORES SÉRICOS PARA DETECÇÃO PRECOCE DE CÂNCER DE PULMÃO
Authors: Carneiro Ellis Neide Alves , Dagios Mariana da Silva , Batista Maisa Pereira , Freitas Camila Melo de , Costa José Henrique Cardoso Ferreira da , Figueiredo Camile Tripári Cordeiro , Rocha Ana Carolina da Silva , Pinchemel Neto Newton Rubens , Sousa Igor Martins Godoy de , Sampaio Bruno Franco
Published: August 2023

O resumo do artigo "Identificação de Biomarcadores Séricos para Detecção Precoce de Câncer de Pulmão" abrange os principais aspectos abordados no estudo, destacando os avanços, desafios e perspectivas relacionados à busca por indicadores moleculares para diagnóstico precoce da doença.

 

O artigo investiga a identificação de biomarcadores séricos que possam ser utilizados como indicadores eficazes na detecção precoce do câncer de pulmão, uma abordagem fundamental para melhorar as taxas de sobrevivência e resultados clínicos. O estudo examina uma variedade de biomarcadores potenciais, incluindo proteínas, ácidos nucleicos, miRNAs e metabólitos, que refletem as mudanças moleculares associadas ao câncer de pulmão nos estágios iniciais.

 

A pesquisa destaca a promissora capacidade desses biomarcadores séricos em fornecer informações valiosas sobre a presença do câncer de pulmão, muitas vezes antes que sintomas clínicos se manifestem. A revisão dos estudos aponta para uma diversidade de candidatos promissores, cuja análise poderá ser realizada individualmente ou em combinação para maximizar a sensibilidade e a especificidade do diagnóstico.

 

No entanto, o resumo também reconhece os desafios enfrentados nesse campo, incluindo a necessidade de validação clínica rigorosa em estudos prospectivos de grande escala, bem como a padronização de métodos de coleta, armazenamento e análise de amostras. Além disso, o resumo enfatiza a importância da colaboração multidisciplinar entre pesquisadores, clínicos e indústria para avançar na aplicação clínica desses biomarcadores.

Em última análise, o resumo conclui destacando que a identificação de biomarcadores séricos para a detecção precoce do câncer de pulmão representa uma abordagem promissora e inovadora, com o potencial de transformar os métodos de diagnóstico e melhorar os resultados clínicos para os pacientes afetados por essa doença grave. A pesquisa contínua nesse campo é essencial para a validação clínica e o desenvolvimento de estratégias de diagnóstico mais eficazes e sensíveis.
PATOLOGIAS E TRATAMENTOS ASSOCIADOS AO USO DE PRÓTESES TOTAIS REMOVÍVEIS: UMA REVISÃO INTEGRATIVA
Authors: Melo Maria Wilka Samylla Rodrigues , Oliveira Victor Flávio de Oliveira e , Braga Filho Daniel da Silva , Roriz Vinicius de Moraes , Salvador Lucas Samuel de Oliveira , Miranda Jaqueline da Silva , Leite Gleison Lopes , Silva Liza Beatriz Pessoa , Sales Laura Soares , Nascimento Sidrayton Pereira do
Published: August 2023

Objetivo: identificar na literatura científica as características das patologias mais comumentes, tratamentos e alterações ligadas ao uso de próteses totais removíveis em pacientes adultos e idosos, uma vez que são facilitadoras de doenças bucais e lesões orais apresentando diferentes níveis de gravidade. Método: revisão integrativa, cujos critérios de elegibilidade dos artigos foram: corresponder aos descritores “Próteses”; “Patologia oral” e “Reabilitação oral”, ser artigo de pesquisa; estar nos idioma português e inglês; estar disponível eletronicamente nas bases de dados BVS (Biblioteca Virtual em Saúde) e as fontes de dados Scientific Eletronic Library onLine (SciELO) e ano de publicação referente ao período de 2013 a 2023. Resultados: encontraram-se 10 publicações expressivas. A análise ocorreu mediante leituras analítica e interpretativa. A importância das intervenções educativas, inovações, tratamentos afim de minimizar os impactos negativos advindos de perdas dentárias assim como a manutenção impresumível de próteses dentarias afetando a qualidade de vida . Considerações finais: Destacaram-se as próteses totais como indicações positivas para pacientes totalmente edêntulos que são acometidos por suas funções orais essenciais.
Guided in vitro chondrogenesis of bone marrow stromal cells using signaling molecules and genetic engineering
Authors:   , Franco Rose Ann Gabriel
Published: August 2023

The chondrogenic differentiation of bone marrow stromal cells (BMSCs) often leads to hypertrophy, limiting their potential for cartilage repair. While previous attempts to regenerate functional cartilage using various approaches have fallen short of achieving the quality of articular hyaline cartilage, this study explores manipulation of growth factors during culture, the use of signaling pathway inhibition and gene modification to guide BMSC microtissue towards stable chondrogenesis with reduced hypertrophy.
The influence of workforce diversity and organisational culture on innovation in very small information technology entities
Authors:   , Nonoyama Tatsuya
Published: August 2023

Innovation is important for the survival of information technology (IT) firms. Small IT firms, also known as Very Small Entities (VSEs), may capitalise on their workforce diversity to enhance innovation. In this research, VSEs refers to small IT/service-based firms with between 15 and 25 employees. The main challenge for VSEs is that their workforce often lacks the diversity and experience to enhance innovation. The generic workforce diversity practices of large firms are often too complex for VSEs to implement due to major differences in financial situations and organisational culture.
Burial history and hydrocarbon generation model of the Lower–Middle Jurassic sediments in the Tarnovo depression
Authors: Botoucharov Nikola
Published: August 2023

This study deals with the geodynamic evolution in the Tarnovo depression, contributes to a better understanding of the burial and thermal history, and gives a model of the generation of hydrocarbons from the Lower–Middle Jurassic rocks. The implications of the complex heat flow scenario for the timing of hydrocarbon generation from the Stefanets Member of the Etropole Formation in selected sections were also analyzed. The Tarnovo depression is defined as a small tectonic unit in the central part of the South Moesian Platform margin developed mainly during the Early–Middle Jurassic. Therefore, the sediment subsidence during the Early–Middle Jurassic is largely a consequence of the tectonic processes in an extensional basin with tilted, fault-bounded, and eventually rotated blocks. There is a trend of increasing tectonic and basin subsidence in southern direction, observed in modeled well sections. The Lower–Middle Jurassic rocks enter the “oil window” in the late Barremian, Hauterivian, or even the late Valanginian towards the south, starting active generation in the middle Aptian. The model shows that gas generation is possible only in the southern and marginal zones of the Tarnovo depression. Among the sequence, the Stefanets Member of the Etropole Formation (Aalenian–early Bajocian in age), composed of shales and siltstones, possesses source rock qualities and good hydrocarbon generation potential. The research model argues for peak of the oil generation from the Stefanets Member at the end of the Barremian up to the Albian to the north and gas generation starting in the Barremian and continuing during the Cenozoic only in the southern part.
Reaction mechanism of investors of new energy vehicle enterprises to China’s program of retrogressive subsidies in the context of COVID-19 pandemic: Based on the event study method
Authors: Li Zhi , Xie Yundong ,   International Institute of Finance, School of Management, University of Science and Technology of China, Hefei 230601, China
Published: August 2023

In recent years, the subsidy policy of new energy vehicles (NEVs) has promoted the vigorous development of China’s NEV industry. In the past, scholars tended to focus on consumers’ reactions to subsidy policies for NEVs, while attention to the reaction of investors is relatively scarce, especially in the context of major public emergencies. Based on the event study method, this study empirically tested the reaction mode of investors of NEV enterprises to China’s program of retrogressive subsidies (PRS) in the context of COVID-19 pandemic and discussed the differences in investors’ reactions under different enterprise attributes (i.e., whether listed on the Shanghai Stock Exchange, whether located in a first-tier city, whether belonging to state-owned enterprises, and whether belonging to the upstream NEV industry). Our research results provide a reference for the strategic management practices of NEV enterprises and their investors.
Supply chain optimization considering consumers’ mental accounting by time dimension in advance selling
Authors: Nan Yining , Chen Yuan , Nie Tengfei , Du Shaofu ,   School of Management, University of Science and Technology of China, Hefei 230026, China,   School of Management, Shandong University, Jinan 250100, China
Published: August 2023

Advance selling activities based on e-commerce platforms have received much attention from consumers, which is a two-stage sales mode. However, many consumers have indicated that they are relatively happy to pay a deposit and feel more burdened at the final payment stage. That is, consumers feel differently at the two moments even though they know they will pay the same total amount for the product. This psychological behavior can be explained by mental accounting, which means the cognitive-computational process by which individuals or households code, evaluate, and record financial behavior. With the use of advance selling, this research has developed a game theoretical model to investigate how consumers’ mental accounting affects the optimal pricing and ordering decisions of supply chain members under wholesale price and revenue sharing contracts. The analysis shows that under wholesale price contracts, regardless of the optimal wholesale price set by the supplier, a portion of consumers will forgo the deposit paid, and the optimal order quantity for the retailer will always be equal to the consumers’ demand at the final payment stage. In exceptional cases, the optimal wholesale price may be equivalent to the retail price. The supplier’s optimal wholesale price increases monotonically with the consumer’s time coefficient for the price and decreases monotonically with the consumer’s time coefficient for product valuation. Furthermore, under a revenue sharing contract, there is a situation where the supplier’s optimal wholesale price is equal to cost. Additionally, a supplier’s optimal wholesale price exists such that none of the consumers will forgo the deposit they have paid. The study contributes to the understanding of mental accounting in advance selling and has implications for supply chain contract design.
Tratamento cirúrgico e ortodôntico de Mesiodente: relato de caso
Authors: Costa Juliana Dantas da , Oliveira Maria Lucia Rodrigues de , Carvalho Diego Armando Leite , Pinheiro Thyciana Rodrigues , Castro-Silva Igor Iuco , Santiago Sérgio Lima , Pimenta José Luciano Couto
Published: August 2023

Mesiodente é um elemento dentário supranumerário encontrado entre os incisivos maxilares em região de linha média. Esta anomalia está frequentemente associada a desordens de erupção e alinhamento dos incisivos superiores. É mais comum encontrá-los em pacientes do sexo masculino e na dentição permanente. Quanto à morfologia, podem ser encontrados na forma cônica ou tubercular, apresentando uma raiz curta. O tratamento visa a remoção cirúrgica do elemento, desde que não prejudique o desenvolvimento radicular dos dentes adjacentes, e caso necessário, uma posterior intervenção ortodôntica. O objetivo deste trabalho foi apresentar um relato de caso de mesiodente em paciente do sexo masculino, 6 anos de idade, compareceu à clínica acompanhado de seu responsável legal relatando queixa estética e atraso na erupção dos elementos 11 e 21. Após o diagnóstico clínico e radiográfico, foi realizada a exérese do elemento supranumerário e tratamento ortodôntico para corrigir a má oclusão instalada relacionada aos incisivos centrais superiores. O diagnóstico precoce e o tratamento adequado apresentam grande importância no desenvolvimento do sistema estomatognático e psicossocial de crianças e adolescentes, pois a presença do mesiodente pode gerar más oclusões e queixas estéticas no indivíduo acometido.
Pengaruh Customer Experince di Era Digitalisasi Terhadap Retensi Pelanggan pada Industri Retail
Authors: Suriansha Reza
Published: August 2023

Efektifitas manajemen Customer Experince atau  pengalaman pelanggan di seluruh touchpoints, adalah kunci untuk membangun komitmen pelanggan, retensi, dan kesuksesan finansial berkelanjutan. Penelitian ini merupakan penelitian kualitatif yang dilakukan melalui program digitalisasi retail. Sumber yang digunakan dalam penulisan data ini adalah data sekunder dengan metode kualitatif. data sekunder berupa referensi data dalam penulisan karya ilmiah sumbernya diperoleh dari jurnal, artikel dan penulisan sebelumnya. Hasil penelitian menunjukkan bahwa customer experience dengan memanfaatkan digitalisasi   dapat membantu meningkatkan retensi pelanggan. Transformasi digital membuat semua stakeholder harus menawarkan solusi yang kreatif dan memiliki nilai tambah agar produk mereka bisa bersaing di pasar. Solusi yang ditawarkan pun harus memiliki biaya yang murah dan mudah untuk didapatkan oleh pelanggan, serta mampu menjangkau semua elemen pengguna di Indonesia yang tidak bisa dijangkau oleh layanan saat ini. Ketiga hal ini merupakan manfaat digital yang bisa terwujud jika transformasi digital berhasil dilakukan.
Pengaruh Supervisi Kepala Sekolah, Lingkungan Kerja Dan Motivasi Kerja Terhadap Kinerja Guru Smk Muhammadiyah 6 Donomulyo Kabupaten Malang
Authors: Wicaksono Adinda Bagus , Handoko Yunus , Ruspitasari Widi Dewi
Published: August 2023

SMK Muhammadiyah 6 Donomulyo Kabupaten Malang adalah salah satu sekolah menengah kejuruan (SMK) yang telah dipilih sebagai Sekolah Menengah Kejuruan Pusat Keunggulan. Program SMK Pusat Keunggulan ini bertujuan untuk mengembangkan SMK dengan fokus pada kompetensi keahlian tertentu, dengan tujuan meningkatkan kualitas dan kinerja sekolah. Program ini diperkuat melalui kerjasama dan sinergi dengan dunia usaha, industri, dan lapangan kerja. Kemampuan seorang guru dalam menjalankan tugas pembelajaran di sekolah dikenal sebagai kinerja guru. Kinerja guru adalah hasil dari pekerjaannya dan kemampuan serta motivasinya dalam menjalankan tugas-tugas seperti merancang program pembelajaran, mengajar, melakukan evaluasi, dan menganalisis hasil evaluasi. Penelitian ini bertujuan untuk mengidentifikasi dan mengevaluasi dampak dari beberapa faktor terhadap kinerja guru. Faktor-faktor tersebut meliputi 1) pengaruh supervisi kepala sekolah terhadap kinerja guru, 2) pengaruh lingkungan kerja terhadap kinerja guru, 3) pengaruh motivasi kerja terhadap kinerja guru, dan 4) pengaruh supervisi kepala sekolah, lingkungan kerja, dan motivasi kerja secara bersamaan terhadap kinerja guru. Jenis penelitian ini adalah penelitian penjelasan (explanatory research) yang menggunakan pendekatan survei (survey). Penelitian ini dilaksanakan di SMK Muhammadiyah 6 Donomulyo, Kabupaten Malang, antara bulan April hingga Mei 2023. Sampel penelitian terdiri dari 41 guru sebagai responden, dan metode pengambilan sampel yang digunakan adalah non-probability sampling dengan penerapan teknik sampel jenuh. Hasil penelitian menunjukkan beberapa temuan penting. Pertama, supervisi kepala sekolah memiliki dampak yang signifikan terhadap kinerja guru. Kedua, tidak ada pengaruh yang signifikan dari lingkungan kerja terhadap kinerja guru. Ketiga, motivasi kerja memiliki pengaruh yang signifikan terhadap kinerja guru. Terakhir, supervisi kepala sekolah, lingkungan kerja, dan motivasi kerja secara bersama-sama mempengaruhi kinerja guru.
Strategi Pengelolaan Manajemen Sumber Daya Manusia pada Kinerja Karyawan dalam Menghadapi Era Revolusi Industri 4.0
Authors: Marthalia Lia
Published: August 2023

Tantangan terbesar Indonesia dalam menghadapi era Revolusi Industri 4.0 adalah kesenjangan digital akibat minimnya pengetahuan SDM dalam mengoptimalkan teknologi digital dan infrastruktur Teknologi Revolusi Industri 4.0. Oleh karena itu, kesiapan SDM sangat diperlukan untuk menghadapi tantangan di era disrupsi 4.0, maka diperlukan strategi pengelolaan manajemen SDM agar dapat mendukung kinerja karyawan lebih optimal. Tujuan dari penelitian ini yaitu untuk mengetahui strategi pengelolaan manajemen sumber daya manusia pada kinerja karyawan dalam menghadapi era revolusi industri 4.0. Jenis penelitian ini adalah penelitian kualitatif. Lokasi penelitian berada di Jakarta. Sumber data pada penelitian ini yaitu data primer dan data sekunder. Data primer diperoleh langsung melalui wawancara, sedangkan data sekunder diperoleh melalui dokumentasi berupa artikel, buku dan mencari referensi terkait pada permasalahan strategi pengelolaan MSDM pada kinerja karyawan. Teknik analisis data menggunakan tiga tahapan reduksi, penyajian data dan verifikasi. Hasil penelitian adalah strategi pengelolaan manajemen sumber daya manusia pada kinerja karyawan dalam menghadapi era revolusi industri 4.0 bukan sekedar pelatihan, pendidikan, pembinaan, rekrutmen, perubahan sistem, kesempatan, dan penghargaan. Tetapi SDM juga harus meningkatkan kreativitas dan mengubah pola pikir tetap ke pola pikir berkembang, agar siap beradaptasi dan merevolusi diri terhadap perkembangan teknologi yang pesat, sehingga akan tercipta SDM yang unggul, kreatif, dan inovatif, serta adaptif terhadap revolusi industri 4.0. Sehingga karyawan mampu mengaktualisasi diri dalam pengembangan SDM dan menguasai teknologi digital.
Analisis Keuntungan Investasi Bitcoin dengan IHSG
Authors: Masduki Charis , Nur Chasanah Amalia , Yovita Lenni , Prawitasari Dian
Published: August 2023

Tujuan dari penelitian ini adalah untuk membandingkan return investasi antara Bitcoin dengan Indeks Harga Saham Gabungan (IHSG) menggunakan periode waktu antara April 2013 sampai dengan Maret 2023 dengan rentang waktu 1 tahun, 5 tahun dan 10 tahun. Penelitian ini merupakan penelitian kuantitatif menggunakan metode komparatif. Data yang digunakan adalah data historis Harga Bitcoin dan harga IHSG. Analisis data menggunakan uji Mann-Whitney. Hasil dari penelitian ini menunjukkan bahwa investasi Bitcoin dengan IHSG dalam jangka waktu 1 tahun dan 5 tahun Tidak terdapat perbedaan pengembalian investasi antara Bitcoin dengan IHSG, sedangkan jangka waktu 10 tahun terdapat perbedaan pengembalian atau return investasi antara Bitcoin dengan IHSG.
Work Ideologies of Juvenile Probation Officers: The Effects of Individual Characteristics
Authors: Jenkins Keenan Sheri , Daquin Jane
Published: August 2023

Probation is the oldest and most widely used community-based corrections program. Research on probation primarily focuses on the experiences of justice-involved juveniles and the supervision of juveniles in the probation system. Much less is understood about the impact probation officers' perceptions have on job performance and what factors influence those perceptions. The current study aimed to examine the relationship between individual characteristics (e.g., age, gender, race, level of education, tenure, political party affiliation, and jurisdiction) and juvenile probation officers' perceptions about their work ideology. Data for the study came from a sample of juvenile probation officers in nine states. Participants were asked questions about sanctioning, disposition, and role orientation. The study's findings show that few individual characteristics are significantly associated with attitudes/perceptions about work ideology. Probation officers’ race was the only predictor significantly associated with several outcomes. Implications and future directions for research are discussed.
Media Flipchart dalam Pembelajaran Kosa Kata Bahasa Arab
Authors: Fahrurrozi Muhammad , Suparmanto Suparmanto , Alparizi Salman , Mardawiah Mufidatul
Published: August 2023

Mufrodat for students is not easy, learning is boring and contains rote material making students’ interest in learning and student’ abiliti to study the material decrease. The use of flipchart media can help students improve their ability to interpret arabic. This study aims to determine the effectiveness of flipchart media to improve language mufrodat skills arab. The method used is qualitative research. The results of using this flipchart media show that this media is very effective for use in arabic vocabulary. This flipchart media can be used as an alternative arabic learning tool to help students become better arabic interpreters. Mufrodat for students is not easy, learning is boring and contains rote material making students’ interest in learning and student’ abiliti to study the material decrease. The use of flipchart media can help students improve their ability to interpret arabic. This study aims to determine the effectiveness of flipchart media to improve language mufrodat skills arab. The method used is qualitative research. The results of using this flipchart media show that this media is very effective for use in arabic vocabulary. This flipchart media can be used as an alternative arabic learning tool to help students become better arabic interpreters
Peningkatan Kosakata Bahasa Arab melalui Media Teka Teki Silang Bergambar di Kelas V SD Al Ashriyyah Nurul Iman Parung- Bogor
Authors: Parhan Parhan , Safii Mohamad , Rozaq Abdul
Published: August 2023

This study aims to obtain an overview of the implementation of the use of Pictorial Crossword Puzzles in improving Arabic Vocabulary for fifth grade students of SD Al Ashriyyah Nurul Iman Ds. Waru Jaya Kec. Parung Kab. Bogor Province West Java. This research is a classroom action research which consists of two cycles, each cycle includes planning, implementation, observation, and reflection. The data collection techniques used in this study were tests, observations, interviews, and documentation. Based on the results of the research that has been carried out, it shows that Pictorial Crossword Puzzle Media can increase the Arabic vocabulary of fifth grade students of SD Al Ashriyyah Nurul Iman Ds. Waru Jaya Kec. Parung Kab. Bogor Province West Java. The increase in Arabic vocabulary for fifth grade students of SD Al Ashriyyah Nurul Iman Ds. Waru Jaya Kec. Parung Kab. Bogor Province West Java, can be seen from memorization and pronunciation, intonation, application, sentence structure, writing lafadz. From the results of the action research conducted by the researcher, it can be concluded that the Arabic vocabulary of the fifth grade students of SD Al Ashriyyah Nurul Iman Ds. Waru Jaya Kec. Parung Kab. Bogor Province West Java by using the application of Pictorial Crossword Puzzles to increase significantly. The students are more enthusiastic and focused in carrying out Arabic learning activities
The Impact of the Resort-Based Borobudur Highland Master Plan as an Integrated Tourism Area
Authors: Siregar Aisyah Astinadia
Published: August 2023

Tourism in Indonesia has quite good potential and is one of the sectors that spurs the economy in Indonesia. Development of Borobudur Highland which is included in the five super priority tourist destinations. One of them is the construction of hotels and resorts in the Menoreh Hills, Purworejo Regency, Central Java. The master plan was made as a tourism area plan under the Borobudur Authority Agency (BOB) covering an area of ​​309 hectares (ha). This master plan consists of five zones, namely the exclusive resort zone, the entry gate zone, the adventure zone, the cultural zone and the extreme zone. There are three themes in the development of this area, namely ecotourism, cultural tourism and adventure tourism. The method used is using descriptive qualitative. Data collection techniques through interviews, observation, and documentation. The data analyzed using the SWOT matrix. The results of this research can increase the existence of tourism objects in the Purworejo and Kulonprogo areas to international class that are sustainable, educative, and provide new breakthroughs that have an impact on investment in employment and local products around the area. The threats that can occur are changes in rainwater catchment areas to become prone to landslides, loss of springs, damage to ecosystems due to logging of trees, and disruption of existing flora and fauna habitats.
Evaluasi Program Magang Oleh Training Section Dalam Meningkatkan Kinerja Trainee Di Royal Ambarrukmo Yogyakarta
Authors: Hermalia Putri
Published: August 2023

Various strategies and activities carried out by the Human Resources Department (HRD) to enhance Trainee performance during the internship program, such as appropriate Trainee selection, development of suitable training programs, monitoring and evaluation of Trainee performance, and the establishment of a sustainable internship program, can be the focus of this final project. Additionally, it can also discuss the impact of the internship program and the role of the Training Section in creating a conducive work environment for Trainees to contribute maximally to the companyThis research utilizes a qualitative method with data collection through interviews and questionnaires. The researcher will distribute several questionnaires to the Trainees and conduct interviews with the Training Section. Purposive sampling is employed in this study, where 10 Trainees from each department will be intentionally selected to represent their respective departments. The total sample obtained is 40 out of a population of 128.After conducting questionnaires, interviews, and observations with 40 Trainees, the three main components of the internship program that can enhance Trainee performance are job description, training and development programs, and performance monitoring and evaluation. The Trainee's performance is assessed based on 10 components, with the highest being improvement achieved and the lowest being initiatives.
Pengembangan Soal Asesmen Kompetensi Minimum Berbasis Literasi Numerasi
Authors: Taufik Azin , Riyadi Mohamad , Nurhayati Nunu
Published: August 2023

Implementasi kurikulum Merdeka Belajar pada satuan pendidikan menuntut tenaga pendidik untuk mampu memahami konsep dan pelaksanaan kurikulum Merdeka Belajar. Salah satu asesmen yang dilakukan oleh pemerintah dalam mengevaluasi dan memberikan tindak lanjut dari hasil evaluasi adalah dengan adanya Asesmen Nasional Berbasis Komputer (ANBK). Pada pelaksanaan ANBK terdapat Asesmen Kompetensi Minimum (AKM), AKM ini mengukur kemampuan peserta didik dalam kompetensi literasi numerasi. Dalam upaya mendukung suksesnya pelaksanaan AKM tersbut, maka perlu diadakan pelatihan pengembangan soal Asesmen Kompetensi Minimum berbasis literasi numerasi kepada tenaga pendidik. Dengan mengenalkan dan menerapkan soal-soal tersebut dalam pembelajaran di kelas diharapkan peserta didik akan lebih siap dan terbiasa dalam mengerjakan soal berbasis literasi numerasi. Target luaran dalam kegiatan ini adalah dihasilkannya satu buah artikel yang akan diterbitkan pada jurnal nasional dan dihasilkannya soal-soal AKM. Kegiatan pengabdian ini dilaksanakan dalam bentuk pemberian pelatihan kepada tenaga pendidik pada Kelompok Kerja Madrasah Aliyah 3 Kabupaten Cirebon. Kegiatan dilaksanakan selama 3 hari yaitu pada tanggal 22, 23 dan 24 September 2022. Hasil dari kegiatan ini adalah telah dihasilkan soal Asesmen Kompetensi Minimum berbasis literasi numerasi pada mata pelajaran matematika. Evaluasi yang dilakukan dalam bentuk tugas berupa pembuatan soal-soal AKM.
Biodegradation of polyethylene, biodegradable-polyethylene bags and corn residues using Tenebrio molitor larvae
Authors: Mier Mabel Vaca , Reyes-Lomelí Karla Patricia , Cervantes-Cabrera Getsemani , Mata-Guadarrama Miguel Ángel , López-Callejas Raymundo , Rojas-Valencia María Neftalí
Published: August 2023

Se estudió la capacidad de degradación de distintos tipos de plástico a partir de su ingestión por gusanos de la harina (larvas de Tenebrio molitor), así como su supervivencia. Se utilizaron bolsas construidas con plástico denominado polietileno de baja densidad (LDPE); plástico compostable, fabricado a partir de residuos de maíz (CPE); y plástico de polietileno con tecnología d2w (d2wPE).

Las larvas de T. molitor fueron sometidas a un periodo de inanición de 7 días y luego alimentadas únicamente con los distintos tipos de plásticos durante 56 días. Se prepararon dos grupos de muestras con los diferentes plásticos. Por un lado, los plásticos se expusieron a un pretratamiento de fotodegradación UV de 260 a 285 nm y luego se utilizaron como única fuente de alimento para las larvas. Por otro lado, se realizó el mismo experimento sin el pretratamiento UV. El objetivo era comparar los posibles efectos de la radiación UV sobre los plásticos y su posterior degradación por las larvas.

Las tasas máximas de degradación con pretratamiento UV fueron del 98%, 77% y 4% para las muestras de CPE, LDPE y d2wPE, respectivamente. Las tasas de degradación sin pretratamiento fueron del 79%, 54% y 3%, y se obtuvieron en el mismo orden. En ambos escenarios, la supervivencia de las larvas sólo se vio afectada significativamente en las muestras de d2wPE, alcanzando una tasa media de mortalidad del 98%. Para el resto de las muestras, la tasa media de mortalidad fue sólo del 12%.
PENGARUH PERSAHABATAN TERHADAP KEAKTIFAN KEGIATAN LITURGI KAUM MUDA DI LINGKUNGAN SANTO PETRUS PAROKI SANTO VINCENTIUS A PAULO MALANG
Authors: Aryasena Gathan`
Published: August 2023

Sahabat memegang peranan penting dalam kehidupan setiap orang. Selain dari keluarga, biasanya seseorang dalam hal ini kaum muda akan menimba banyak pengaruh baik yang bersifat positif maupun negatif dari sahabat-sahabatnya. Yang dimaksud dalam penelitian ini adalah persahabatan rohani kaum muda yang ada di lingkungan Santo Petrus Paroki Santo Vincentius a Paulo Malang khususnya dalam bidang liturgi atau pengudusan. Banyak kegiatan liturgi yang diikuti oleh kaum muda di lingkungan Santo Petrus antara lain mengikuti kegiatan doa lingkungan, pendalaman iman dan kegiatan liturgi di Gereja sebagai lector, pemazmur dan misdinar. Tujuan penelitian ini adalahuntuk melihat apakah ada  pengaruh dari persahabatan terhadap keaktifan kegiatan liturgi kaum muda di lingkungan Santo Petrus Paroki Santo Vincentius a Paulo Malang. Adapun teknik pengambilan sampel dengan tehnik purposive sampling artinya pengambilan data dengan kriteria tertentu dalam hal ini hanya kaum muda yang betul-betul aktif dalam kegiatan liturgi. Untuk metode pengumpulan data menggunakan metode kuesioner, sedangkan instrumennya ialah angket dengan skala empat (4) tingkat. Untuk kuesionernya tertutup di mana peneliti sudah menentukan jawaban sehingga responden tinggal memilih. Angket yang disebar sebanyak dua puluh (20) tetapi angket yang kembali delapan belas (18). Pengambilan data dilakukan pada bulan November 2022. Dari analisa data  ternyata hasilnya berpengaruh yaitu dari 18 kaum muda  diperoleh hasil rata-rata 64,16 %. Ini menunjukkan bahwa kegiatan liturgia yang diikuti dan dijalankan oleh kaum muda berpengaruh dimana antara kaum muda yang satu mempengaruhi kaum muda yang lain untuk ambil bagian dalam kegiatan liturgi baik di gereja maupun di lingkungan
MENINGKATKAN KEMAMPUAN MEMBACA PERMULAAN MELALUI MEDIA GAMBAR BAGI ANAK TUNAGRAHITA SEDANG DI SDLB BHAKTI LUHUR MALANG
Authors: Desa Maria Vianti
Published: August 2023

Setiap orang berhak memperoleh kesempatan dalam belajar, karena dengan belajar membaca orang akan mampu untuk memahami dan mengerti dengan baik. Membaca merupakan  kemampuan yang kompleks sebagai satu kesatuan proses psikologis dan perkembangan keterampilan. Membaca merupakan proses pengenalan kata, memahami kata-kata, dan suatu keterampilan yang wajib dimiliki  oleh anak. Membaca permulaan merupakan kegiatan dimana anak belum bisa membaca maka perlu dikenalkan huruf. Kesempatan belajar membaca terbuka bagi semua orang termasuk anak tunagrahita sedang.  Kondisi keterbatasan tunagrahita sedang, dalam menerima dan menangkap informasi mempengaruhi kemampuan membaca  di SDLB Bhakti Luhur Malang  kelas C1. Ada 3 anak tunagrahita sedang belum bisa membaca permulaan. Langkah yang diambil melatih membaca permulaan menggunakan media gambar. Tujuannya membuktikan bahwa melalui media gambar dapat meningkatkan kemampuan membaca permulaan anak tunagrahita sedang. Jenis penelitian adalah desain eksperimen digunakan pre eksperimen dalam bentuk one group pretest-posttest. Penelitian ini dilaksanakan di SDLB Bhakti Luhur Malang kelas C1 yang  terdiri dari 3 anak tunagrahita sedang. Hasil yang diperoleh setelah diberi perlakuan untuk 3 anak tunagrahita mengalami peningkatan dalam membaca permulaan yaitu FD, memperoleh rata-rata 17,5%   untuk latihan meniru, mencocokan, mengenal huruf dan mengeja suku kata. AB, memperolah nilai rata- rata 25% latihan meniru, mencocokan, mengenal huruf dan mengeja suku kata.  CE, memperoleh  nilai rata- rata 27,5%  dalam meniru, mencocokan, mengenal huruf dan mengeja suku kata.
Penguatan Sikap Pro-sosial melalui Kegiatan Pramuka untuk Mencegah Kekerasan di Sekolah Inklusif
Authors: Subasno Yohanes , Dacosta Fransiska , Syamsudin . , Gracia Sakristi Maria Antonia
Published: August 2023

Kegiatan kepramukaan merupakan kegiatan yang menginternalisasi sikap tata nilai baik bagi peserta didik. Kendati pramuka merupakan ekstrakurikuler, namun sebagian besar isi kegiatannya berwujud penanaman sikap dan tindakan pro-sosial yang diperlukan peserta didik sebagai generasi muda. Sikap pro-sosial berkaitan dengan berbagi, kerjasama, menolong, jujur, kedermawanan, dan mempertimbangkan hak dan kesejahteraan orang lain. Penelitian ini bertujuan untuk menggambarkan persepsi siswa SMPK Bhakti Luhur Malang terhadap kontribusi penguatan sikap pro-sosial dalam kegiatan pramuka, sebagai upaya pencegahan kekerasan. Metode penelitian yang diterapkan adalah mix-method, yakni penggabungan pendekatan kuantitatif untuk mendeskripsikan persepsi siswa dan pendekatan kualitatif sebagai data pendukung. Seluruh siswa kelas VIII dan IX yang berjumlah 28 menjadi responden, dan 4 orang yang terdiri dari pembina pramuka, wali kelas, dan kepala sekolah menjadi informan dalam penelitian ini. Data dikumpulkan menggunakan angket mengacu pada skala model Likert dan panduan wawancara. Data kuantitatif dianalisis menggunakan persentase dan grafik, sedangkan data kualitatif dianalisis dengan pendekatan Miles and Huberman. Hasil penelitian menyatakan persepsi siswa terhadap sikap berbagi memperoleh skor 79.9%, kerjasama dan menolong 82.6%, kejujuran 70.3%, kedermawanan 76.1%, memperhatikan hak orang lain 76.6%, dengan rerata 78.0% (berkontribusi sangat tinggi). Hasil tersebut dikonfirmasi oleh hasil penelitian kualitatif yang menyatakan bahwa antarsiswa saling berbagai mainan dan alat tulis, bekerjasama dalam menolong teman terutama yang berkebutuhan khusus, bersikap dermawan dengan membagi bekal pada siswa lain, berempati pada orang lain. Pada unsur kejujuran, beberapa siswa masih menyontek saat ujian dan memberi alasan tidak benar ketika datang terlambat
Creativity of the linguistic personality of a columnist in the media discourse (based on the Russian and German languages)
Authors: Хачмафова З.Р.
Published: August 2023

Статья посвящена проблеме изучения лингвокреативных средств актуализации авторской позиции в дискурсе колумнистики. Выявлены и проанализированы маркеры креативности языковой личности колумниста в медиадискурсе (метафора, языковая игра, фразеологизмы, использование прецедентных текстов). Изучены когнитивные основы порождения креативности языковой личности колумниста в дискурсе СМИ в аспекте реализации непрямого воздействия на массового адресата. Лингвокреативность в дискурсе СМИ рассматривается как механизм непрямого воздействия на массового адресата.

The article aims to study linguocreative means of updating the author's position in the discourse of author`s columns. The author identifies and analyzes markers of the creativity of a columnist`s linguistic personality in the media discourse such as metaphor, language game, phraseological units and use of precedent texts. The cognitive basics of generating the creativity of a columnist's linguistic personality in the media discourse are studied as means of indirect impact on the audience. Linguistic creativity in the media discourse is considered as a mechanism of indirect influence on the masses.
SHORT STORY TEXT TEACHING MATERIALS ORIENTED ON CRITICAL THINKING ABILITY FOR HIGH SCHOOL STUDENTS
Authors: Nurul Inayah  , Abdul Rozak  , Dede Endang Mascita
Published: August 2023

This research was to obtain digital teaching materials for short story texts oriented towards critical thinking skills for high school students. Learning is an activity planned and facilitated by the teacher which aims to change student behavior for the better. Teaching materials can help and guide students in carrying out learning activities so that students' mastery of the subject matter becomes better. Short stories are stories that are physically short and can be read in one sitting. The research method that the author will use in this study is the Research and Development (R&D) method. This study uses the ADDIE research and development model method. The ADDIE development design stages are as follows: analysis, design, development, implementation, and evaluation. Aspects of content or material obtained a percentage of 81,25%, aspects of presentation of material obtained a percentage of 75,00%, aspects of language and readability obtained a percentage of 81,25%, graphic aspects obtained a percentage of 90,00%. The results of the overall percentage of four aspects, namely content or material aspects, material presentation aspects, language and readability aspects, and graphic aspects obtained a score of 82.45%. Based on the results of these scores, the digital learning module for short story texts oriented towards critical thinking skills is included in the sufficiently valid criteria. Based on the results of the analysis of students' needs for teaching materials by the teacher and students, it can be concluded that students need teaching materials for short story texts oriented towards thinking skills for class XI high school students. Short story text learning modules oriented towards critical thinking skills for class XI high school students can be used as an alternative learning, because this teaching material is in accordance with the demands of the curriculum and according to the needs of students
Efeitos de uma educação permanente no conhecimento de enfermeiros acerca da fibrilação atrial
Authors: Costa Adriele , Silva Camila de Souza da , Flores Anderson , Teló Fernanda Ceolin , Beffart Milena Luisa , Eberhardt Thaís Dresch
Published: August 2023

Tem-se como objetivo analisar os efeitos de uma atividade de educação permanente em enfermagem acerca da Fibrilação Atrial. Trata-se de um estudo antes e depois, realizado com enfermeiros de uma unidade de emergência de um hospital do Rio Grande do Sul, de agosto a outubro de 2022, desenvolvida em três etapas (t0 pré-teste; t1 intervenção educativa e pós-teste; t2 pós-teste 30 dias após t1). Os dados foram analisados por meio de estatística descritiva simples. Em t0 foi identificado uma média de acertos de 4,0 questões. Após a educação permanente, a média de acertos foi de 7,0; 30 dias após a educação permanente, a média de acertos foi de 6,1. A questão que a educação permanente mais teve efeito foi sobre as complicações mais frequentes da FA. Conclui-se que a educação permanente teve efeito positivo no conhecimento dos enfermeiros da unidade de emergência, tendo diminuído seu efeito após 30 dias.
Incidência de casos de tuberculose em Santos (SP): características dos casos notificados nos anos de 2017 a 2021
Authors: Bezerra Thiago Augusto Rochetti , Paschoal Juliana Fontes Beltran , Vicente Marcela , Ranéia e Silva Priscila Andrade
Published: August 2023

A tuberculose continua como uma das doenças mais frequentes no mundo e é considerada um grande problema de saúde pública. Dados apresentados mostram que o Brasil foi responsável por 30% dos casos notificados de tuberculose nas Américas em 2016. O presente estudo objetiva analisar o padrão epidemiológico da tuberculose na cidade de Santos nos anos de 2017 a 2021.  Trata-se de um estudo ecológico descritivo com uso de dados secundários, os dados foram expressos em número absoluto e, para possível efeito de comparação, foi utilizado o cálculo do coeficiente de incidência. Verificou-se uma predominância dos casos novos de tuberculose no sexo masculino e surpreendentemente a faixa etária entre 15 e 49 anos, como de maior risco à infecção.  O conhecimento da situação epidemiológica da tuberculose ao longo dos anos fornece subsídios para o direcionamento de recursos em áreas de risco e às novas estratégias de prevenção e controle da doença, além de garantir maior mobilização das entidades responsáveis para que as medidas preventivas e de controle sejam satisfatórias na população de Santos.
Alcaloide milonina: atividades biológicas e farmacológicas uma revisão da literatura
Authors: De Melo Santos Gleyka Daisa , Ferreira Hávila , Silva Thallys , Silva Teresinha
Published: August 2023

A milonina é um alcaloide do tipo morfinânico, isolado das folhas da Cissampelos sympodialis Eichl. Ensaios preliminares já haviam demonstrado o potencial biológico da milonina. Entretanto, avanços experimentais nesse sentido ainda são escassos. Este estudo trata-se de uma revisão bibliográfica, que teve como objetivo reunir evidências científicas acerca das propriedades farmacológicas da milonina. Foram selecionados dez estudos que melhor atenderam ao objetivo da revisão. Os achados destacaram que o alcaloide apresenta consideráveis efeitos cardiovasculares, anti-inflamatórios, anti-histamínicos, antioxidantes e citotóxicos, destacando, portanto, o quão importantes e promissores são estes dados, uma vez que apoiam e impulsionam a realização de mais estudos, visando o desenvolvimento de novas estratégias terapêuticas envolvendo o emprego da milonina.
Alfabetização na pós-pandemia: uma proposta a partir dos indicadores educacionais à luz da perspectiva discursiva de alfabetização
Authors: Mendes de Oliveira Rayannie , Ribeiro Pinto Glenda , Dominices Coutinho Fernandes Vanja Maria
Published: August 2023

O presente estudo tem por objetivo analisar dados dos indicadores acerca do processo de alfabetização de crianças das escolas públicas brasileiras em tempos de pandemia e pós-pandemia, elucidando os impactos da covid-19 no processo de alfabetização das mesmas. Para que fosse possível trilhar o percurso metodológico, lançamos mão da pesquisa bibliográfica, da pesquisa qualitativa e quantitativa. Para tal análise, fizemos uso dos dados divulgados pelos indicadores educacionais, sendo eles: Índice de Desenvolvimento da Educação Básica (Ideb), Pesquisa Nacional por Amostra de Domicílios Contínua (Pnad-c) e o Sistema de Avaliação da Educação Básica (Saeb). No que se refere aos resultados acerca da alfabetização das crianças no período da pandemia e pós-pandemia, constatou-se que houve aumento considerável, a partir de 2021, no percentual de crianças que não sabiam ler e escrever no país, segundo dados da Pesquisa Nacional por Amostra de Domicílios Contínua (Pnad-c). Nesse bojo, acreditamos ser pertinente propor sugestões de intervenção a partir da perspectiva discursiva de linguagem à luz de Bakhtin (1998), Geraldi (2011), Smolka (2012), Jolibert (2006), dentre outros.
Contribuições do uso do GeoGebra no ensino de funções polinomiais no 1º ano do ensino médio
Authors: Araujo Weslay de , Lopes Renata , Cole Bruno , Freitas Antônio , Dos Santos Kristian , Lustosa Iuri
Published: August 2023

O presente trabalho tem por objetivo mostrar como o uso do software GeoGebra pode contribuir para o ensino de funções polinomiais de primeiro e segundo grau no 1º ano do ensino médio, visto que este conteúdo se apresenta de difícil entendimento quando usados apenas quadro, pincel, lápis e papel. Inicialmente é feita uma explanação sobre a importância das Tecnologias Digitais de Informação e Comunicação (TDIC) na educação. O aporte teórico mostra desde a inclusão das tecnologias em sala de aula, perpassa pela importância do uso do GeoGebra no ensino de funções e chega à necessidade do professor em saber manusear esse tipo de software. Notou-se através do referencial teórico utilizado e também da sequência didática apresentada, que o software GeoGebra mostra-se como um importante recurso que facilita o ensino de Matemática, em especial aqui trabalhado, o ensino de funções polinomiais, bem como é uma maneira de usar TDIC em sala de aula, tão presente no cotidiano dos estudantes
Aspectos etnobotânicos, fitoquímicos e farmacológicos da espécie Siparuna guianensis Aublet: revisão sistemática
Authors: Rodrigues Elizângela Sofia Ribeiro , Moreira Rodrigo De Faveri , Santos Naiane Oliveira , Soares Wagner Rodrigues de Assis , Lima Emersom Silva , Aguiar Raimundo Wagner de Souza
Published: August 2023

A espécie Siparuna guianensis Aublet é conhecida pelo uso etnobotânico atribuído a povos tradicionais ribeirinhos e comunidades indígenas da América Central e do Sul para tratar dores, inflamações e infecções. O objetivo deste estudo foi descrever o uso etnomedicinal e verificar as propriedades fitoquímicas e farmacológicas da espécie. Foi realizado um estudo de revisão sistemática, com o termo Siparuna guianensis Aublet combinado aos descritores fitoquímico ou farmacológico. O uso etnomedicinal foi confirmado em estudos controlados. Foram identificados 96 metabólitos secundários, das classes dos alcaloides, flavonoides e terpenoides entre outros. Propriedade anti-inflamatória, antioxidante, antinociceptiva, bactericida, antifúngica, neuroprotetora, antiparasitária, inseticida e como bio repelente foram confirmadas em estudos in silico, in vivo e in vitro. Pesquisas de toxicidade aguda e subcrônica demonstraram baixa toxicidade e ausência de respostas mutagênicas. Tais achados apontam a possibilidade da utilização da espécie para tratar doenças ligadas ao estresse oxidativo, inflamações e infecções, e podem ser úteis para nortear futuras aplicações biotecnológicas como formulações fitoterápicas a partir da espécie.
A relação mulher e trabalho no livro didático: uma análise enunciativa
Authors: Gonçalves Garcia Ana Laura , Schreiber da Silva Soeli
Published: August 2023

Este artigo tem o intuito de abordar a mulher em enunciações dos textos de livros didáticos. Mais especificamente, a mulher e sua relação com o trabalho. O preconceito de gênero é um tema demandado mais assiduamente nos dias de hoje e para compreender seus sentidos enunciativos será necessária a análise das expressões: mulher e trabalho, com base na Semântica do Acontecimento, por meio da descrição do espaço de enunciação que é o livro didático. O corpus selecionado foi o livro didático de linguagens e códigos aprovado pelo Programa Nacional do Livro Didático (PNLD), da editora Ática. Com isso, a finalidade é além de ancorar-se na analítica de Eduardo Guimarães, que busca identificar os sentidos semânticos enunciativos dos textos, mostrar as condições relacionada a exclusão da mulher em um local de influência.