bluuebunny/crossref_metadata_2025 huggingface dataset:
Signal Processing Application Based on a Hybrid Wavelet Transform to Fault Detection and Identification in Power System
Authors: Nasser Mohamed Yasmin , Seker Serhat , Akinci Tahir Cetin
Published: October 2023

The power system is one of the most susceptible systems to failures, which are most frequently caused by transmission line faults. Transmission line failures account for 85% of all power system malfunctions. However, over the last decade, numerous fault detection methods have been developed to ensure the reliability and stability of power systems. A hybrid detection method based on the idea of redundancy property is presented in this paper. Because the continuous wavelet transform itself does not extract fault features for small defects effectively, the stationary wavelet transform approach is employed to assist in their detection. As a result of its ability to decompose the signal into high- and low-frequency components, undecimated reconstruction by using the algebraic summation operation (ASO) is used. This approach creates redundancy, which is useful for the feature extraction of small defects and makes faulty parts more evident. The numerical value of the redundancy ratio’s contribution to the original signal is approximately equal to 36%. Following this method for redundant signal reconstruction, a continuous wavelet transform is used to extract the fault characteristic significantly easier in the time-scale (frequency) domain. Finally, the suggested technique has been demonstrated to be an efficient fault detection and identification tool for use in power systems. In fact, using this advanced signal processing technique will help with early fault detection, which is mainly about predictive maintenance. This application provides more reliable operation conditions.
Predictive Factors Associated with Successful Response to Percutaneous Adhesiolysis in Chronic Lumbar Radicular Pain
Authors: Kose Halil Cihan , Akkaya Omer Taylan
Published: October 2023

Percutaneous adhesiolysis (PEA) is of interest in the treatment of lumbar radicular pain. This study aimed to assess the effectiveness of PEA in patients with chronic lumbar radicular pain refractory to epidural steroid injections and to determine predictive factors, including demographic, clinical, and procedural data, to provide superior treatment efficacy. One hundred and ninety-three patients were reviewed. Successful treatment outcome was described as a 50% reduction in the visual analog scale score. Among the 193 patients, 109 (56.2%) exhibited a positive treatment response at 12 months. In multivariate logistic regression analysis, no depression (OR, 3.105; 95% CI, 1.127–8.547; p = 0.028), no spondylolisthesis (OR, 2.976; 95% CI, 1.246–7.092; p = 0.014), no previous lumbar surgery (OR, 2.242; 95% CI, 1.067–4.716; p = 0.033), mild foraminal stenosis (OR, 3.460; 95% CI, 1.436–8.333; p = 0.006), no opioid use (OR, 1.782; 95% CI, 0.854–3.717; p = 0.123), and baseline pain scores (OR, 0.787; 95% CI, 0.583–1.064; p = 0.120) were the predictive factors significantly associated with unsuccessful treatment outcome. PEA is a useful treatment option for patients with chronic lumbar radicular pain refractory to epidural steroid injections. A history of lumbar surgery, spondylolisthesis, depression, and severe foraminal stenosis could be associated with a poor prognosis.
Autoimmune Pancreatitis Type 1 with Biliary, Nasal, Testicular, and Pulmonary Involvement: A Case Report and a Systematic Review
Authors: Kourie Mourad , Bogdanovic Darko , Mahmutyazicioglu Kamran , Ghazi Sam , Panic Nikola , Fjellgren Eva , Hellkvist Laila , Thiel Tomas , Kjellman Anders , Kartalis Nikolaos , Danielsson Olof , Dani Lara , Löhr J.-Matthias , Vujasinovic Miroslav
Published: October 2023

Introduction: Immunoglobulin G4-related disease (IgG4-RD) is an immune-mediated condition associated with fibroinflammatory lesions that can occur at almost any anatomical site. It often presents as a multiorgan disease that may mimic malignancy, infection, or other immune-mediated conditions. Autoimmune pancreatitis (AIP) type 1 is the most prominent manifestation of IgG4-RD in the digestive tract, with common extra-pancreatic inflammation. We present the first patient with AIP and involvement of the testicles and nasal cavity. Patient and methods: A case of a patient with AIP type 1 and other organ involvement (bile ducts, testicles, nasal polyps, and lungs) is described. Additionally, a systematic review of AIP type 1 with testicular and nasal involvement was conducted. Results: The systematic review found two cases of AIP type 1 with testicular involvement and 143 cases with AIP type 1 with nasal cavity involvement. None of them had both testicular and nasal involvement. Conclusions: This is the first case of AIP type 1 with other organ involvement, including testicular and nasal involvement, to be described. The number of patients with nasal and testicular involvement described in the literature is low. Creating awareness of this rare clinical condition is necessary, especially due to the very effective available treatment with corticosteroids and rituximab.
Fatigue, Depression and Health-Related Quality of Life in Patients with Post-Myocardial Infarction during the COVID-19 Pandemic: Results from the Augsburg Myocardial Infarction Registry
Authors: Meisinger Christa , Kirchberger Inge , Raake Philip , Linseisen Jakob , Schmitz Timo
Published: October 2023

The interplay between fatigue and depression and their association with health-related quality of life (HRQoL) after acute myocardial infarction (AMI) has received little attention during the COVID-19 pandemic. Therefore, this study evaluated the frequency of fatigue and depression in post-AMI patients during the COVID-19 pandemic and investigated the cross-sectional associations between fatigue, depression and HRQoL. Methods: The analysis was based on population-based Myocardial Infarction Registry Augsburg data. All survivors of AMI between 1 June 2020 and 15 September 2021 were included (n = 882) and received a postal questionnaire containing questions about fatigue (Fatigue Assessment Scale), depression (Patient Health Questionnaire), and HRQoL (MacNew Heart Disease HRQoL questionnaire) on 17 November 2021. The questionnaire was returned by 592 patients (67.1%), and 574 participants could be included in the analysis. Multivariable linear regression models were performed to investigate the associations between fatigue and depression (both exposures) and HRQoL (outcome). Results: Altogether, 273 (47.6%) participants met the criteria for the presence of fatigue, about 16% showed signs of moderate to severe depression. Both fatigue and depression were significantly associated with a decreased HRQoL (total score and emotional, social, and physical subscales; all p-values < 0.0001). In particular, a combined occurrence of fatigue and depression was associated with a significantly reduced HRQoL. Conclusions: It seems necessary to screen post-MI patients for the presence of fatigue and depression in clinical practice on a routine basis to provide them with adequate support and treatment and thus also to improve their HRQoL.
Qualification of the PAVIN Fog and Rain Platform and Its Digital Twin for the Evaluation of a Pedestrian Detector in Fog
Authors: Segonne Charlotte , Duthon Pierre
Published: October 2023

Vehicles featuring partially automated driving can now be certified within a guaranteed operational design domain. The verification in all kinds of scenarios, including fog, cannot be carried out in real conditions (risks or low occurrence). Simulation tools for adverse weather conditions (e.g., physical, numerical) must be implemented and validated. The aim of this study is, therefore, to verify what criteria need to be met to obtain sufficient data to test AI-based pedestrian detection algorithms. It presents both analyses on real and numerically simulated data. A novel method for the test environment evaluation, based on a reference detection algorithm, was set up. The following parameters are taken into account in this study: weather conditions, pedestrian variety, the distance of pedestrians to the camera, fog uncertainty, the number of frames, and artificial fog vs. numerically simulated fog. Across all examined elements, the disparity between results derived from real and simulated data is less than 10%. The results obtained provide a basis for validating and improving standards dedicated to the testing and approval of autonomous vehicles.
Diversity of CO2 Concentrating Mechanisms in Macroalgae Photosynthesis: A Case Study of Ulva sp.
Authors: Sun Jingyi , Zhao Chunyan , Zhao Shuang , Dai Wei , Liu Jinlin , Zhang Jianheng , Xu Juntian , He Peimin
Published: October 2023

Many algae respond to the CO2 limitation in seawater by inducing a CO2 concentrating mechanism (CCM) to obtain sufficient inorganic carbon to meet their photosynthetic needs, and Ulva sp. is a model population suitable for studying the ecological adaptability of macroalgae. As the dominant species of green tide disaster, Ulva sp. often faces strong inorganic carbon restriction due to its rapid growth and high population density and must have evolved a variety of carbon acquisition strategies, such as CCM, to overcome these limitations. This paper briefly summarizes the position and function of the important components of CCM (inorganic carbon transporters, carbonic anhydrase, Rubisco, and pyrenoid) and introduces several indexes suitable for evaluating the relative function of CCMs in macroalgae from the aspects of affinity between photosynthesis and Rubisco for CO2, and carbonic anhydrase inhibitor. The methods of judging the carbon sequestration pathway of Ulva sp., the CCM responses of diversity under different carbon sources, and the related genes that may be involved in the operation of CCMs were summarized. This work could provide a reference for revealing the CCMs of macroalgae and lay a foundation for further research on the inorganic carbon utilization strategy of the Ulva sp.
Object Recognition Scheme for Digital Transformation in Marine Science and Engineering
Authors: Choi Jinseo , An Donghyeok , Kang Donghyun
Published: October 2023

With the advancement of deep learning (DL), researchers and engineers in the marine industry are exploring the application of DL technologies to their specific applications. In general, the accuracy of inference using DL technologies is significantly dependent on the number of training datasets. Unfortunately, people in marine science and engineering environments are often reluctant to share their documents (i.e., P&ID) with third-party manufacturers or public clouds to protect their proprietary information. Despite this, the demand for object detection using DL technologies in image-formatted files (i.e., jpg, png, or pdf format) is steadily growing. In this paper, we propose a new mechanism, called a no-training object picker (NoOP), which efficiently recognizes all objects (e.g., lines, tags, and symbols) in image-formatted P&ID documents. Notably, it can recognize objects without any training dataset, thus reducing the time and effort required for training and collection of unpublished datasets. To clearly present the effectiveness of NoOP, we evaluated NoOP using a real P&ID document. As a result, we confirmed that all objects in the image-formatted P&ID file are successfully detected over a short time (only 7.11 s on average).
Urgent Off-Label Use of Flow–Diverter Stents in the Endovascular Management of Tonsillar Loop-Associated Internal Carotid Artery Dissections Presenting with Carotid Occlusion or Near-Occlusion and Major Ischemic Stroke
Authors: Cohen José E. , Filioglo Andrei , Gomori John Moshe , Honig Asaf , Leker Ronen R. , Henkes Hans
Published: October 2023

We present our experience with the implantation of flow diverter stents (FDSs) for the management of internal carotid artery (ICA) dissections in tortuous tonsillar loop segments. A total of 16 patients (10 women, 62.5%; mean age 39 ± 8 years; median baseline NIHSS 13; median ASPECTS 8.5) with acute ischemic stroke due to ICA dissection in a tortuous tonsillar loop segment, with/without large intracranial vessel thrombotic occlusion diagnosed between June 2015–February 2022 were included in this retrospective study under a waiver of informed consent. An FDS device was deployed from the petrous ICA toward the upper cervical ICA, completely covering the tonsillar loop. Stentriever-assisted thrombectomy was performed when indicated. A dual antiplatelet regimen was used during and after the procedure. Thrombocyte inhibition levels were evaluated before, during, and after the intervention. The ICA occlusion/near occlusion was successfully recanalized in all 16 patients with mean postangioplasty residual stenosis of 34 ± 14% (range 0–50%). Stent-assisted thrombectomy was performed in 15/16 patients (93.7%), achieving revascularization (TICI 2b–3) in all. There were no procedural complications and no intraprocedural embolic events; one asymptomatic petechial hemorrhage was detected. At 3-month follow-up, mRS 0–2 was seen in all patients. This report provides pilot data for a subsequent study on the use of flow diverter stents for ischemic cerebrovascular conditions. Our encouraging preliminary results await confirmation from further experience and prospective randomized studies.
Environmental Sustainability in Vineyards under a Protected Designation of Origin in View of the Implementation of Photovoltaic Solar Energy Plants
Authors: Arias-Navarro Irene , Del Campo-Gomis Francisco José , Agulló-Torres Asunción M. , Martinez-Poveda África
Published: October 2023

Environmental sustainability is a fundamental asset in the development of all agricultural policies within the European Union. However, its practical application is finding important incompatibilities between several of its objectives, such as the preservation of the landscape and action against climate change, through the exploitation of renewable energies systems. Indeed, Spain and its viticulture under PDOs are facing an exponential dilemma: the change in use of agricultural wine grape producing land to install solar panels for renewable energy generation. Therefore, this study aims to provide an assessment of the community where the Alicante PDO is based, on the environmental sustainability of its vineyards in view of the implementation of photovoltaic solar energy plants, and to identify an optimal and socially sustainable design. Online research techniques ensuring anonymity were used, achieving a valuation of the quality of the wine-growing landscape and its associated cultural heritage in the territory of the of Alicante PDO. However, as the importance of solar energy generation is also valued, the preferred alternative would be a limited combination of use and design to maintain the wine-growing landscape. These terms should be reflected by competent administrations when authorizing future installations in the Alicante PDO.
Exploring Health-Related Quality of Life in Patients with Anal Fistulas: A Comprehensive Study
Authors: Mateescu Tudor , Fulger Lazar , Tummala Durganjali , Nelluri Aditya , Kakarla Manaswini , Stelea Lavinia , Dumitru Catalin , Noditi George , Dobrescu Amadeus , Paleru Cristian , Toma Ana-Olivia
Published: October 2023

Anal fistulas often cause significant impairment to patients’ health-related quality of life (HRQOL). This cross-sectional study aimed to compare the HRQOL between patients with anal fistulas with inflammatory bowel disease (IBD) and those without, hypothesizing significant differences in HRQOL scores between these groups. The secondary objectives were to identify specific aspects of life quality most affected and explore potential variables influencing HRQOL. The study was conducted at the Clinical Emergency Hospital “Pius Brinzeu” in Timisoara, Romania, using a convenience sample of 175 adult patients diagnosed with anal fistulas, stratified into IBD and non-IBD groups. Quality of life was evaluated at initial hospital admission and three months post-treatment using four questionnaires: SF-36, GIQLI, HADS, and the WHOQOL-BREF. Initial SF-36 scores were marginally lower in the IBD group, with mean physical and mental scores of 52.0 and 54.5, respectively. Both groups showed an improvement after intervention, but the mean difference was higher in the IBD group, with an increase of 1.1 in physical score. Initial GIQLI scores were significantly lower in the IBD group (110) compared to the non-IBD group (116). Post-intervention, the mean scores increased to 116 and 121, respectively. HADS scores suggested higher anxiety levels in the non-IBD group (7.5 vs. 6.1), although depression scores were similar. Post-intervention, anxiety scores decreased more substantially in the non-IBD group (−0.9 vs. −0.3). The WHOQOL-BREF scores were lower across all domains for the IBD group at the initial test (physical health: 12.4, psychological health: 14.9, social relationships: 14.4, environment: 13.0). Post-intervention, scores increased marginally in the IBD group (physical health: 12.7, psychological health: 15.9, social relationships: 14.1, environment: 13.8) but varied in the non-IBD group. HRQOL, as measured by multiple questionnaires, is impacted differently in anal fistula patients with and without IBD. These findings highlight the importance of a tailored approach to managing this patient population to improve their quality of life post-treatment.
Testing the Homogeneity of Differences between Two Proportions for Stratified Bilateral and Unilateral Data across Strata
Authors: Zhang Xueqing , Ma Changxing
Published: October 2023

Medical comparative studies often involve collecting data from paired organs, which can produce either bilateral or unilateral data. While many testing procedures are available that account for the intra-class correlation between paired organs for bilateral data, more research needs to be conducted to determine how to analyze combined correlated bilateral and unilateral data. In practice, stratification is often used in analysis to ensure participants are allocated equally to each experimental condition. In this paper, we propose three Maximum Likelihood Estimation (MLE)-based methods for testing the homogeneity of differences between two proportions for stratified bilateral and unilateral data across strata using Donner’s model. We compare the performance of these methods with a model-based method based on Generalized Estimating Equations using Monte Carlo simulations. We also provide a real example to illustrate the proposed methodologies. Our findings suggest that the Score test performs well and offers a valuable alternative to the exact tests in future studies.
Efficient Monitoring of a Parameter of Non-Normal Process Using a Robust Efficient Control Chart: A Comparative Study
Authors: Chaudhary Aamir Majeed , Sanaullah Aamir , Hanif Muhammad , Almazah Mohammad M. A. , Albasheir Nafisa A. , Al-Duais Fuad S.
Published: October 2023

The control chart is a fundamental tool in statistical process control (SPC), widely employed in manufacturing and construction industries for process monitoring with the primary objective of maintaining quality standards and improving operational efficiency. Control charts play a crucial role in identifying special cause variations and guiding the process back to statistical control. While Shewhart control charts excel at detecting significant shifts, EWMA and CUSUM charts are better suited for detecting smaller to moderate shifts. However, the effectiveness of all these control charts is compromised when the underlying distribution deviates from normality. In response to this challenge, this study introduces a robust mixed EWMA-CUSUM control chart tailored for monitoring processes characterized via symmetric but non-normal distributions. The key innovation of the proposed approach lies in the integration of a robust estimator, based on order statistics, that leverages the generalized least square (GLS) technique developed by Lloyd. This integration enhances the chart’s robustness and minimizes estimator variance, even in the presence of non-normality. To demonstrate the effectiveness of the proposed control chart, a comprehensive comparison is conducted with several well-known control charts. Results of the study clearly show that the proposed chart exhibits superior sensitivity to small and moderate shifts in process parameters when compared to its predecessors. Through a compelling illustrative example, a real-life application of the enhanced performance of the proposed control chart is provided in comparison to existing alternatives.
Diagnostic Value of Immunological Biomarkers in Children with Asthmatic Bronchitis and Asthma
Authors: Wu Ming , Liu Danru , Zhu Fenhua , Yu Yeheng , Ye Zhicheng , Xu Jin
Published: October 2023

Background and Objectives: This study aimed to investigate the diagnostic value of immunological biomarkers in children with asthmatic bronchitis and asthma and to develop a machine learning (ML) model for rapid differential diagnosis of these two diseases. Materials and Methods: Immunological biomarkers in peripheral blood were detected using flow cytometry and immunoturbidimetry. The importance of characteristic variables was ranked and screened using random forest and extra trees algorithms. Models were constructed and tested using the Scikit-learn ML library. K-fold cross-validation and Brier scores were used to evaluate and screen models. Results: Children with asthmatic bronchitis and asthma exhibit distinct degrees of immune dysregulation characterized by divergent patterns of humoral and cellular immune responses. CD8+ T cells and B cells were more dominant in differentiating the two diseases among many immunological biomarkers. Random forest showed a comprehensive high performance compared with other models in learning and training the dataset of immunological biomarkers. Conclusions: This study developed a prediction model for early differential diagnosis of asthmatic bronchitis and asthma using immunological biomarkers. Evaluation of the immune status of patients may provide additional clinical information for those children transforming from asthmatic bronchitis to asthma under recurrent attacks.
May Nutritional Status Positively Affect Disease Progression and Prognosis in Patients with Esophageal and Pharyngeal Cancers? A Scoping Review of the Current Clinical Studies
Authors: Antasouras Georgios , Papadopoulou Sousana K. , Tolia Maria , Pandi Aimilia-Lynn , Spanoudaki Maria , Tsoukalas Nikolaos , Tsourouflis Gerasimos , Psara Evmorfia , Mentzelou Maria , Giaginis Constantinos
Published: October 2023

Background: Malnutrition in esophageal and pharyngeal cancer patients constitutes a common and serious concern, which significantly reduces patients’ prognoses. Cancers of the esophagus and the pharynx can considerably impair feeding in patients, resulting in severe undernutrition. This is a scoping review that intends to critically analyze the most well-designed clinical studies investigating the potential beneficial impact of diverse nutritional assessment tools on the prognosis of patients with esophageal and pharyngeal cancers. Methods: The most accurate and remarkable scientific databases were comprehensively explored utilizing relative keywords to detect clinical studies that investigate whether nutritional status may affect disease prognosis. Results: Several assessment tools have evaluated and highlighted the potential beneficial impact of nutritional status on disease progression and patients’ prognosis in both esophageal and pharyngeal cancers. Regarding esophageal cancer, CONUT, PNI, PG-SGA, and NRS-2002 are more commonly used, while albumin is also frequently evaluated. Regarding pharyngeal cancers, fewer studies are currently available. PNI has been evaluated, and its significance as a factor for shorter survival’ times has been highlighted. The Comprehensive Nutritional Index has also been evaluated with positive results, as well as NRS 2002, GPS, and body-weight status. However, there is currently a lack of studies with an adequate number of women with cancer. An international literature gap was identified concerning follow-up studies with adequate methodology. Conclusions: Nutritional status may significantly affect disease progression and patients’ survival, highlighting the significance of a great nutritional status in individuals with esophageal and pharyngeal cancers. Further large-scale and well-designed prospective surveys should be performed to verify the potential beneficial effects of adequate nourishment in people suffering from cancer of the esophagus and pharynx.
A South African Perspective on the Microbiological and Chemical Quality of Meat: Plausible Public Health Implications
Authors: Manyi-Loh Christy E. , Lues Ryk
Published: October 2023

Meat comprises proteins, fats, vitamins, and trace elements, essential nutrients for the growth and development of the body. The increased demand for meat necessitates the use of antibiotics in intensive farming to sustain and raise productivity. However, the high water activity, the neutral pH, and the high protein content of meat create a favourable milieu for the growth and the persistence of bacteria. Meat serves as a portal for the spread of foodborne diseases. This occurs because of contamination. This review presents information on animal farming in South Africa, the microbial and chemical contamination of meat, and the consequential effects on public health. In South Africa, the sales of meat can be operated both formally and informally. Meat becomes exposed to contamination with different categories of microbes, originating from varying sources during preparation, processing, packaging, storage, and serving to consumers. Apparently, meat harbours diverse pathogenic microorganisms and antibiotic residues alongside the occurrence of drug resistance in zoonotic pathogens, due to the improper use of antibiotics during farming. Different findings obtained across the country showed variations in prevalence of bacteria and multidrug-resistant bacteria studied, which could be explained by the differences in the manufacturer practices, handling processes from producers to consumers, and the success of the hygienic measures employed during production. Furthermore, variation in the socioeconomic and political factors and differences in bacterial strains, geographical area, time, climatic factors, etc. could be responsible for the discrepancy in the level of antibiotic resistance between the provinces. Bacteria identified in meat including Escherichia coli, Listeria monocytogenes, Staphylococcus aureus, Campylobacter spp., Salmonella spp., etc. are incriminated as pathogenic agents causing serious infections in human and their drug-resistant counterparts can cause prolonged infection plus long hospital stays, increased mortality and morbidity as well as huge socioeconomic burden and even death. Therefore, uncooked meat or improperly cooked meat consumed by the population serves as a risk to human health.
Syntheses, Crystal Structures, and Catalytic Properties of Three Cu(II) and Cobalt(II) Coordination Compounds Based on an Ether-Bridged Tetracarboxylic Acid
Authors: Kang Xiuqi , Wang Hongyu , Mei Zhenzhong , Fan Xiaoxiang , Gu Jinzhong
Published: October 2023

Three new products, [Cu2(μ3-dppa)(2,2′-bipy)2(H2O)]n·2nH2O (1), [Co4(μ4-dppa)2(phen)4(H2O)4]·2H2O (2), and [Co2(μ6-dppa)(μ-4,4′-bipy)(H2O)2]n·3nH2O (3) were synthesized using a hydrothermal method from Cu(II) and Co(II) metal(II) chlorides, 3-(3,4-dicarboxyphenoxy)phthalic acid (H4dppa), and different auxiliary ligands, namely 2,2′-bipyridine (2,2′-bipy),1,10-phenanthroline (phen), and 4,4′-bipyridine (4,4′-bipy). Products 1–3 were characterized by elemental analysis, FTIR, TGA, PXRD, SEM, and single-crystal X-ray crystallography. The structure of 1 features a 1D chain of the 2C1 topological type. Compound 2 shows a discrete tetrameric complex. Product 3 demonstrates a 3D metal–organic framework (MOF) with the new topology. Their structure and topology, thermal stability, and catalytic activity were studied. In particular, excellent catalytic activity was demonstrated for copper(II)-polymer 1 in the cyanosilylation reaction at 35 °C.
Microplastics’ Shape and Morphology Analysis in the Presence of Natural Organic Matter Using Flow Imaging Microscopy
Authors: Kim Soyoun , Hyeon Yejin , Park Chanhyuk
Published: October 2023

Ubiquitous microplastics in urban waters have raised substantial public concern due to their high chemical persistence, accumulative effects, and potential adverse effects on human health. Reliable and standardized methods are urgently needed for the identification and quantification of these emerging environmental pollutants in wastewater treatment plants (WWTPs). In this study, we introduce an innovative rapid approach that employs flow imaging microscopy (FlowCam) to simultaneously identify and quantify microplastics by capturing high-resolution digital images. Real-time image acquisition is followed by semi-automated classification using customized libraries for distinct polyethylene (PE) and polystyrene (PS) microplastics. Subsequently, these images are subjected to further analysis to extract precise morphological details of microplastics, providing insights into their behavior during transport and retention within WWTPs. Of particular significance, a systematic investigation was conducted to explore how the presence of natural organic matter (NOM) in WWTPs affects the accuracy of the FlowCam’s measurement outputs for microplastics. It was observed that varying concentrations of NOM induced a more curled shape in microplastics, indicating the necessity of employing pre-treatment procedures to ensure accurate microplastic identification when utilizing the FlowCam. These observations offer valuable new perspectives and potential solutions for designing appropriate treatment technologies for removing microplastics within WWTPs.
Photo-Induced, Phenylhydrazine-Promoted Transition-Metal-Free Dehalogenation of Aryl Fluorides, Chlorides, Bromides, and Iodides
Authors: Zhu Yiwei , Wu Zhimin , Sun Hongcai , Ding Junjun
Published: October 2023

In this study, we present a straightforward and highly effective photo-triggered hydrogenation method for aryl halides, devoid of transition-metal catalysts. Through the synergistic utilization of light, PhNHNH2, and a base, we have successfully initiated the desired radical-mediated hydrogenation process. Remarkably, utilizing mild reaction conditions, a wide range of aryl halides, including fluorides, chlorides, bromides, and iodides, can be selectively transformed into their corresponding (hetero)arene counterparts, with exceptional yields. Additionally, this approach demonstrates a remarkable compatibility with diverse functional groups and heterocyclic compounds, highlighting its versatility and potential for use in various chemical transformations.
Coumarins from Jinhua Finger Citron: Separation by Liquid–Liquid Chromatography and Potential Antitumor Activity
Authors: Wang Chaoyue , Huang Jiangang , Zhou Zhiling , Xu Ping , Shi Jingyi , Yang Yushun , Tong Shengqiang , Hu Hongyu
Published: October 2023

In this paper, liquid–liquid chromatography was introduced for the first time for the separation of fingered citron (Citrus medica L. var. sarcodactylis Swingle). The fingered citron cultivated in Jinhua is of significant industrial and medicinal value, with several major coumarin compounds detected in its extract. Therefore, further separation for higher purity was of necessity. A preparative liquid–liquid chromatographic method was developed by combining two elution modes (isocratic and step-gradient) with selection according to different polarities of the target sample. Five coumarin derivatives—5,7-dimethoxycoumarin (52.6 mg, 99.6%), phellopterin (4.9 mg, 97.1%), 5-prenyloxy-7-methoxycoumarin (6.7 mg, 98.7%), 6-hydroxy-7-methoxycoumarin (7.1 mg, 82.2%), and byakangelicol (10.5 mg, 90.1%)—with similar structures and properties were isolated on a large scale from 100 mg of petroleum ether (PE) extract and 100 mg of ethyl acetate (EA) extract in Jinhua fingered citron. The productivity was much improved. The anti-growth activity of the isolated coumarins was evaluated against three cancer cell lines (HeLa, A549, and MCF7) with an MTT assay. The coumarins demonstrated potential anti-tumor activity on the HeLa cell line, with 5,7-dimethoxycoumarin in particular exhibiting the best anti-growth activity (IC50 = 10.57 ± 0.24 μM) by inhibiting proliferation. It inhibited colony formation and reduced the size of the tumor sphere in a concentration-dependent manner. The main mechanism was confirmed as inducing apoptosis. This work was informative for further studies aimed at exploring new natural-product-based antitumor agents.
Synthesis of Liquid Hydrocarbon via Direct Hydrogenation of CO2 over FeCu-Based Bifunctional Catalyst Derived from Layered Double Hydroxides
Authors: Li Ziqin , Wang Kangzhou , Xing Yaqin , Song Wenlong , Gao Xinhua , Ma Qingxiang , Zhao Tiansheng , Zhang Jianli
Published: October 2023

Here, we report a Na-promoted FeCu-based catalyst with excellent liquid hydrocarbon selectivity and catalytic activity. The physiochemical properties of the catalysts were comprehensively characterized by various characterization techniques. The characterization results indicate that the catalytic performance of the catalysts was closely related to the nature of the metal promoters. The Na-AlFeCu possessed the highest CO2 conversion due to enhanced CO2 adsorption of the catalysts by the introduction of Al species. The introduction of excess Mg promoter led to a strong methanation activity of the catalyst. Mn and Ga promoters exhibited high selectivity for light hydrocarbons due to their inhibition of iron carbides generation, resulting in a lack of chain growth capacity. The Na-ZnFeCu catalyst exhibited the optimal C5+ yield, owing to the fact that the Zn promoter improved the catalytic activity and liquid hydrocarbon selectivity by modulating the surface CO2 adsorption and carbide content. Carbon dioxide (CO2) hydrogenation to liquid fuel is considered a method for the utilization and conversion of CO2, whereas satisfactory activity and selectivity remains a challenge. This method provides a new idea for the catalytic hydrogenation of CO2 and from there the preparation of high-value-added products.
Theoretical Investigation on the “ON-OFF” Mechanism of a Fluorescent Probe for Thiophenols: Photoinduced Electron Transfer and Intramolecular Charge Transfer
Authors: Wang Yuxi , Zhang Meng , Li Wenzhi , Wang Yi , Zhou Panwang
Published: October 2023

In this study, the sensing mechanism of (2E,4E)-5-(4-(dimethylamino)phenyl)-1-(2-(2,4dinitrophenoxy)phenyl)penta-2,4-dien-1-one (DAPH-DNP) towards thiophenols was investigated by density functional theory (DFT) and time-dependent DFT (TD-DFT). The DNP group plays an important role in charge transfer excitation. Due to the typical donor-excited photo-induced electron transfer (d-PET) process, DAPH-DNP has fluorescence quenching behavior. After the thiolysis reaction between DAPH-DNP and thiophenol, the hydroxyl group is released, and DAPH is generated with the reaction showing strong fluorescence. The fluorescence enhancement of DAPH is not caused by an excited-state intramolecular proton transfer (ESIPT) process. The potential energy curves (PECs) show that DAPH-keto is less stable than DAPH-enol. The frontier molecular orbitals (FMOs) of DAPH show that the excitation process is accompanied by intramolecular charger transfer (ICT), and the corresponding character of DAPH was further confirmed by hole-electron and interfragment charge transfer (IFCT) analysis methods. Above all, the sensing mechanism of the turn-on type probe DAPH-DNP towards thiophenol is based on the PET mechanism.
Angiostrongyliasis: A Changing Scenario?
Authors: Bruschi Fabrizio
Published: October 2023

Angiostrongyliasis is a parasitic disease caused by larvae of the genus Angiostrongylus, with Angiostrongylus cantonensis and Angiostrongylus costaricensis being the two main species causing diseases in humans [...]
Models of Protective Immunity against Schistosomes: Implications for Vaccine Development
Authors: Wilson R Alan
Published: October 2023

After many decades of research, a schistosome vaccine still looks to be a distant prospect. These helminths can live in the human bloodstream for years, even decades, surrounded by and feeding on the components of the immune response they provoke. The original idea of a vaccine based on the killing of invading cercariae in the skin has proven to be illusory. There has also been a realisation that even if humans develop some protection against infection over a protracted period, it very likely involves IgE-mediated responses that cannot provide the basis for a vaccine. However, it has also become clear that both invasive migrating larvae and adult worms must expose proteins and release secretions into the host environment as part of their normal biological activities. The application of modern ‘omics approaches means that we now have a much better idea of the identity of these potential immune targets. This review looks at three animal models in which acquired immunity has been demonstrated and asks whether the mechanisms might inform our vaccine strategies to achieve protection in model hosts and humans. Eliciting responses, either humoral or cellular, that can persist for many months is a challenge. Arming of the lungs with effector T cells, as occurs in mice exposed to the radiation-attenuated cercarial vaccine, is one avenue. Generating IgG antibody titres that reach levels at which they can exert sustained immune pressure to cause worm elimination, as occurs in rhesus macaques, is another. The induction of memory cell populations that can detect trickle invasions of larval stages remains to be explored. One promising approach is the analysis of protective antibodies using high-density peptide arrays of target proteins to identify reactive regions. These can be combined in multi-epitope constructs to immunise a host against many targets simultaneously and cheaply.
Model for Technology Selection in the Context of Industry 4.0 Manufacturing
Authors: Aballay Claudio , Quezada Luis , Sepúlveda Cristián
Published: October 2023

Manufacturing companies face significant challenges due to rapid changes in globalized markets and open economies, which are experiencing mega-trends such as urbanization, globalization, and individualization. For sustainable growth, advanced technology is necessary. However, selecting technology is a difficult task due to the wide variety of options in the market. Technology has become a fundamental strategic factor for the growth and profitability of companies. The main objective of this paper is to propose a model and a methodological proposal for technology selection in the context of Industry 4.0 manufacturing. The proposed methodology is divided into three stages: The first stage is of knowledge and intervention, which allows for the socialization of the model and data collection. The second stage is the operational stage, where a hybrid method of FAHP and FANP is used to determine the weights of the factors considered. Lastly, the third stage is the analysis and evaluation stage, where the analysis, discussion, and evaluation of the results take place. To validate the proposed model, the methodology was applied to two case studies in Chilean industrial companies. The results obtained through the FAHP and FANP algorithms enabled decision makers to manage and select the most suitable technology from the wide variety of options available in today’s markets.
Special Issue on “Advanced Liquid Waste and Gas Waste Treatment Processes”
Authors: Rybarczyk Piotr
Published: October 2023

The development of industry and increasing population result in the growing demand for clean water and air, with higher and higher volumes of sewage and post-process air to be treated [...]
Building a Deposit–Refund System (DRS) for Closed-Loop Recycling of Water Bottles in the United Arab Emirates
Authors: Jadayil Wisam Abu , Aqil Eman
Published: October 2023

Water bottles are widely used in the Gulf countries. One estimate indicates that the water bottle usage in the United Arab Emirates (UAE) may reach up to 250 L of water per person annually. Generally, the water bottles are made of polyethylene terephthalate (PET), a recyclable material. Because of the non-availability of a powerful incentive system, these recyclable water bottles are often disposed of in landfills. This paper proposes a feasibility study of building a Deposit–Refund System (DRS) to encourage the closed-loop recycling of 0.5 L PET water bottles in the UAE waste disposal system. Water bottles are collected by a reverse vending machine (RVM) and recycled to produce PET bottles, and the proposed system will reward consumers with 0.04 United Arab Emirates Dirham (AED) per deposited water bottle. Additionally, this study calculates the cost of 100% virgin polyethylene terephthalate (vPET) and 60% recycled polyethylene terephthalate (rPET) bottles based on the UAE population, data obtained from local water bottle companies, and existing research. Adopting this DRS will cut down on waste, protect the environment, improve the manufacturing process of water bottles, and boost the local economy.
The Impact of Sex and Biological Maturation on Physical Fitness in Adolescent Badminton Players
Authors: Fernandez-Fernandez Jaime , Herrero-Molleda Alba , Álvarez-Dacal Francisco , Hernandez-Davó Jose Luis , Granacher Urs
Published: October 2023

The main objective of this study was to examine the impact of maturity status and sex on selected measures of physical fitness in adolescent badminton players. Eighty-one badminton players (39 boys, 42 girls; age: 12.7 ± 1.4 years; body height: 153.5 ± 10.5 cm; body mass: 48.3 ± 13.2 kg) participated in the study and were divided into pre-peak height velocity (PHV, n = 31), circa-PHV (n = 29), and post-PHV (n = 21) groups. The assessment of physical fitness included linear sprint (5-m, 10-m) and change-of-direction (CoD) speed tests using a modified 5-0-5 CoD test (CoD deficit [CoDD%]) and an on-court CoD test, as well as the countermovement jump (CMJ) test as a proxy of lower limbs’ muscle power. Pre-PHV players presented lower performance levels (p < 0.001; ES: 1.81–1.21) than post-PHV in CMJ, linear sprint (5, 10-m) speed, and both CoD tests. In addition, compared to circa-PHV, pre-PHV players demonstrated moderately lower performances in the 10 m sprint and CoD tests (p < 0.05; ES: 0.65–1.00). Regarding the CoDD%, no between-group differences were found. Irrespective of the maturity status, boys outperformed girls in CMJ (p = 0.01; ES: 0.71), linear sprint speed (p < 0.05, ES: 0.52–0.77), and the modified 505 test (p = 0.01; ES: 0.71). Findings only showed significant sex-by-maturity interactions for the pre-PHV group. In addition, sex-related performance differences were found in favor of the boys for most measures except for CoDD%. Our results imply that maturity status (i.e., PHV) and not chronological age should be used to design training programs. Female adolescent badminton players should receive specifically targeted exercise interventions based on their fitness status and needs.
Volatility Connectedness of Chinese Financial Institutions: Evidence from a Frequency Dynamics Perspective
Authors: Li Yishi , Ni Yongpin , Zheng Hanxing , Zhou Linyi
Published: October 2023

Accurately measuring systemic financial risk and analyzing its sources are important issues. This study focuses on the frequency dynamics of volatility connectedness in Chinese financial institutions using a spectral representation framework of generalized forecast error variance decomposition with the least absolute shrinkage and selection operator vector autoregression. It assesses the volatility connectedness network using complex network analysis techniques. The data are derived from 31 publicly traded Chinese financial institutions between 4 January 2011 and 31 August 2023, encompassing the Chinese stock market crash in 2015 and the COVID-19 pandemic. The frequency dynamics of the volatility connectedness results indicate that long-term connectedness peaks and cross-sectoral connectedness rises during periods of financial instability, especially in the recent bull market (2014–2015) and the 2015 Chinese stock market crash. The volatility connectedness of Chinese financial institutions declined during the COVID-19 pandemic but rose during the post-COVID-19 pandemic period. Network estimation results show that securities triggered the 2015 bull market, whereas banks were the main risk transmitters during the 2015 market crash. These results have important practical implications for supervisory authorities.
Entropy Weighted TOPSIS Based Cluster Head Selection in Wireless Sensor Networks under Uncertainty
Authors: Sen Supriyan , Sahoo Laxminarayan , Tiwary Kalishankar , Senapati Tapan
Published: October 2023

In recent decades, wireless sensor networks (WSNs) have become a popular ambient sensing and model-based solution for various applications. WSNs are now achievable due to the developments of micro electro mechanical and semiconductors logic circuits with rising computational power and wireless communication technology. The most difficult issues concerning WSNs are related to their energy consumption. Since communication typically requires a significant amount of energy, there are some techniques/ways to reduce energy consumption during the operation of the sensor’s communication systems. The topology control technique is one such effective method for reducing WSNs’ energy usage. A cluster head (CH) is usually selected using a topology control technique known as clustering to control the entire network. A single factor is inadequate for CH selection. Additionally, with the traditional clustering method, each round exhibits a new batch of head nodes. As a result, when using conventional techniques, nodes decay faster and require more energy. Furthermore, the inceptive energy of nodes, the range between sensor nodes and base stations, the size of data packets, voltage and transmission energy measurements, and other factors linked to sensor nodes are also completely unexpected due to irregular or hazardous natural circumstances. Here, unpredictability represented by Triangular Fuzzy Numbers (TFNs). The associated parameters of nodes were converted into crisp ones via the defuzzification of fuzzy numbers. The fuzzy number has been defuzzified using the well-known signed distance approach. Here, we have employed a multi-criteria decision-making (MCDM) approach to choosing the CHs depending on a bunch of characteristics of each node (i) residual energy, (ii) the number of neighbors, (iii) distance from the sink, (iv) average distance of cluster node, (v) distance ratio, and (vi) reliability. This study used the entropy-weighted Technique for Order Preference by Similarity to the Ideal Solution (TOPSIS) approach to select the CH in WSNs. For experiments, we have used the NSG2.1 simulator, and based on six characteristics comprising residual energy, number of neighbor nodes, distance from the sink or base station (BS), average distance of cluster nodes, distance ratio, and reliability, optimal CHs have been selected. Finally, experimental results have been presented and compared graphically with the existing literature. A statistical hypothesis test has also been conducted to verify the results that have been provided.