bluuebunny/crossref_metadata_2025 huggingface dataset:
Medical-Sanitary Consequences of Emergency Situations in the World, 2012–2021
Authors:   A.M.Nikiforov Russian Center of Emergency and Radiation Medicine, EMERCOM of Russia, St. Petersburg, Russian Federation, Evdokimov V.I. , Rybnikov V.Yu. ,   A.M.Nikiforov Russian Center of Emergency and Radiation Medicine, EMERCOM of Russia, St. Petersburg, Russian Federation
Published: April 2023

Summary. Investigation purpose – to analyze and summarize data about medical-sanitary consequences of major emergency situations (ES) in the world for last 10 years (2012–2021). Materials and methods of the investigation. An object of investigation – data base about major ES in the world (The Emergency Events Database, EM-DAT: OFDA/CRED) [https://public.emdat.be/]. Average annual data is presented by median, upper and lower quartiles (Me [q25; q75]). Risks of injury, illness or death because of ES were calculated for 1 million people (10–6). Analysis of dynamic of changing medical-sanitary indicators of consequences of major ES in the world were provided by analysis of dynamic series with calculating of 2nd stage polynomial trend and determination coefficient. Investigation results and their analysis. From 2012 till 2021 in EM-DAT data base 5533 major ES were presented, including 877 natural disasters, 1814 technogenic disasters. With low determination coefficients polynomial trends show, as rule, a tendency of ES number reduction, decreasing of risks of injury, illness and appearance of ES with medical-sanitary consequences.
Organization and Provision of Specialized Medical Treatment for Victims with Burns in the Russian Federation
Authors:   A.V.Vishnevskiy Centre of Surgery of Ministry of Healthcare of the Russian Federation, Moscow, Russian Federation, Alekseev A.A. ,   Russian Medical Academy of Continuous Professional Education, the Ministry of Health of the Russian Federation, Moscow, Russian Federation, Malyutina N.B. ,   A.V.Vishnevskiy Centre of Surgery of Ministry of Healthcare of the Russian Federation, Moscow, Russian Federation,   Russian Medical Academy of Continuous Professional Education, the Ministry of Health of the Russian Federation, Moscow, Russian Federation, Bobrovnikov A.E. ,   A.V.Vishnevskiy Centre of Surgery of Ministry of Healthcare of the Russian Federation, Moscow, Russian Federation,   Russian Medical Academy of Continuous Professional Education, the Ministry of Health of the Russian Federation, Moscow, Russian Federation, Filimonov K.A. ,   A.V.Vishnevskiy Centre of Surgery of Ministry of Healthcare of the Russian Federation, Moscow, Russian Federation
Published: April 2023

Summary. Investigation purpose – to research the conditions of organization and provision of specialized medical treatment on the profile “surgery (combustiology)” basing on the data from informational-analytic system “Combustiological treatment in Russia”. Material and methods of the investigation. In the basis of research – reports from 120 medical treatment organizations (MTO) in the year 2021 and some date from previous years reports. Investigation results and their analysis. In 2021 in the Russian Federation a specialized treatment for victims with burns was provided in 63 burns departments/centers, including 7 children departments/centers, and on profiled burns bunks in surgical and combustiological departments. Summary there were 44886 patients with burns and their consequences got treatment. More than 79% of adults and 95% of children with burns entered the stage of specialized treatment at the time less than 72 hours after injury. Average duration of patients stay on the bunks was 17,8 bunk-days – for adults and 11,0 bunk-days – for adults, Summary lethality among the adults was in average number for the Russian Federation 7,7%; among the children – 0,3%. A conclusion was made that improvement of organization and provision of medical treatment on all stages of medical evacuation and treatment of victims with burns allow to improve the nearest and far results of this category of patients treatment.
Realization of Strategy of Sanitary Aviation Development in Omsk Area
Authors:   The National Medical Surgical Center named after N.I. Pirogov, Moscow, Russian Federation, Isaeva I.V. , Kostyuk I.I. ,   Territorial Center for Disaster Medicine of the Omsk Region, Omsk, Russian Federation, Baranova N.N. ,   State Research Center – Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency, Moscow, Russian Federation,   Russian Medical Academy of Continuous Professional Education, the Ministry of Health of the Russian Federation, Moscow, Russian Federation
Published: April 2023

Summary. Investigation purpose – to research and assess an interim results of sanitary aviation development strategy realization in Omsk area. Materials and methods of the investigation. Investigation materials: accounting forms filled in “Disaster medicine centers monitoring” system (smk.minzdrav.gov.ru) by specialists of territorial canter of disaster medicine (TCDM); report form of industry statistic monitoring №56 “An information about an activity of medical organizations which implement an urgent medical treatment provision and medical evacuation conducting on mobile work forms, including organizations having an emergency consulting medical treatment departments” in 2021; Omsk area TCDM work reports. Investigation methods – analytic, statistic Investigation results and their analysis. Changings which happened during improvement of complex of systematic approaches to the organization of emergency form medical treatments provision for population in Omsk area were analyzed. A comparative analysis of avia-medical crews of TCDM work indicators during emergency medical treatment provision with a usage of sanitary aviation in daily and emergency modes were analyzed.
Comparison of Analgesia Schemes Based on Nefopam and Tramadol in Injured with Mine-Explosion Trauma during Conducting of Medical Evacuation by Sanitary Vehicles
Authors:   State Research Center – Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency, Moscow, Russian Federation, Reza A.V. , Baranova N.N. ,   State Research Center – Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency, Moscow, Russian Federation,   Russian Medical Academy of Continuous Professional Education, the Ministry of Health of the Russian Federation, Moscow, Russian Federation
Published: April 2023

Summary. Investigation purpose – to compare an effectivity and safety of implementation of schemes of analgesia based on nefopam and tramadol in conditions of medical evacuation by sanitary vehicles with mine-explosion trauma (MET); to determine a possibility of its usage as an alternative for drugs analgetic. Materials and methods of the investigation. Calls maps (form 110/u) of crews of Center of sanitary aviation and urgent medical treatment of All-Russian Center of Disaster Medicine “Zashchita” of Federal State Budget Organization “SSC – Federal Medical Biophysical Center named after A.I. Burnazyan” of FMBA of Russia. Patients were divided into 2 groups. Each group contained 8 people. A scheme with nefopam and non-steroid anti-inflammation medicines (NSAIM) was used for analgesia in the first group. There was a scheme with tramadol and NSAIM in the second group. Investigation results and their analysis. A usage of nefopam combined with NSAIM in patient with MET in conditions of prolonged medical evacuation by sanitary vehicles is not inferior in its efficiency to the combination of tramadol with NSAIM and has some benefits to stability and frequency of side effects. A nefopam usage as a component of multimodal scheme of analgesia as an alternative to tramadol can be recommended by medical specialists who provide treatment for patients during military actions. Nefopam doesn’t contain in the list of potent and toxic substances. This fact gives organization and logistics benefits during nefopam usage in conditions of emergency situation.
An integrated bioinformatic analysis of bulk and single-cell sequencing clarifies immune microenvironment and metabolic profiles of lung adenocarcinoma to predict immunotherapy efficacy
Authors: Li Mengling , Zhou Baosen , Zheng Chang
Published: April 2023

Targeting the tumor microenvironment is increasingly recognized as an effective treatment of advanced lung adenocarcinoma (LUAD). However, few studies have addressed the efficacy of immunotherapy for LUAD. Here, a novel method for predicting immunotherapy efficacy has been proposed, which combines single-cell and bulk sequencing to characterize the immune microenvironment and metabolic profile of LUAD. TCGA bulk dataset was used to cluster two immune subtypes: C1 with “cold” tumor characteristics and C2 with “hot” tumor characteristics, with different prognosis. The Scissor algorithm, which is based on these two immune subtypes, identified GSE131907 single cell dataset into two groups of epithelial cells, labeled as Scissor_C1 and Scissor_C2. The enrichment revealed that Scissor_C1 was characterized by hypoxia, and a hypoxic microenvironment is a potential inducing factor for tumor invasion, metastasis, and immune therapy non-response. Furthermore, single cell analysis was performed to investigate the molecular mechanism of hypoxic microenvironment-induced invasion, metastasis, and immune therapy non-response in LUAD. Notably, Scissor_C1 cells significantly interacted with T cells and cancer-associated fibroblasts (CAF), and exhibited epithelial–mesenchymal transition and immunosuppressive features. CellChat analysis revealed that a hypoxic microenvironment in Scissor_C1elevated TGFβ signaling and induced ANGPTL4 and SEMA3C secretion. Interaction with endothelial cells with ANGPTL4, which increases vascular permeability and achieves distant metastasis across the vascular endothelium. Additionally, interaction of tumor-associated macrophages (TAM) and Scissor_C1 via the EREG/EFGR pathway induces tyrosine kinase inhibitor drug-resistance in patients with LAUD. Thereafter, a subgroup of CAF cells that exhibited same features as those of Scissor_C1 that exert immunosuppressive functions in the tumor microenvironment were identified. Moreover, the key genes (EPHB2 and COL1A1) in the Scissor_C1 gene network were explored and their expressions were verified using immunohistochemistry. Finally, the metabolism dysfunction in cells crosstalk was determined, which is characterized by glutamine secretion by TAM and uptake by Scissor_C1 via SLC38A2 transporter, which may induce glutamine addiction in LUAD cells. Overall, single-cell sequencing clarifies how the tumor microenvironment affects immunotherapy efficacy via molecular mechanisms and biological processes, whereas bulk sequencing explains immunotherapy efficacy based on clinical information.
Long QTc in hypertrophic cardiomyopathy: A consequence of structural myocardial damage or a distinct genetic disease?
Authors: Cava Francesco , Micolonghi Caterina , Musumeci Maria Beatrice , Petrucci Simona , Savio Camilla , Fabiani Marco , Tini Giacomo , Germani Aldo , Libi Fabio , Rossi Carla , Visco Vincenzo , Pizzuti Antonio , Volpe Massimo , Autore Camillo , Rubattu Speranza , Piane Maria
Published: April 2023

Hypertrophic cardiomyopathy (HCM) is an autosomal dominant disease, characterized by the presence of unexplained left ventricular hypertrophy. This condition is often associated with electrocardiographic abnormalities including QTc prolongation occurring in 13% of patients. The main explanation for prolonged QTc in HCM is myocardial hypertrophy and the related structural damage. However, other mechanisms, including long QT syndrome (LQTS) genes mutations, may be involved. In the present study we explored the hypothesis of a distinct genetic basis underlying QTc prolongation in HCM by investigating the potential co-inheritance of pathogenic gene variants associated with LQTS and HCM. For this purpose, starting from a cohort of 150 HCM patients carrying pathogenic variants in sarcomere genes, we selected 25 patients carrying a QTc prolongation unexplained by any other cause. The QTc was considered prolonged if greater than 450 ms in males and greater than 470 ms in females. The NGS analysis was performed with Illumina TrueSight Cardio panel genes on Illumina MiniSeq platform. We identified pathogenic/likely pathogenic variants in the KCNQ1 in two patients (c.1781G > A, p. Arg594Gln; c.532G > A, p. Ala178Thr) (8%). Variants of uncertain significance were identified in SCN5A, KCNJ5, AKAP9 and ANK2 in four patients (16%). Although the results are limited by the small number of patients included in the study, they highlight a minor contribution of LQTS genes for QTc prolongation in HCM patients. The screening for ion channel genes mutations may be considered in HCM patients with prolonged QTc unexplained by any other cause. This in-depth molecular diagnosis may contribute to improve risk stratification and treatment planning.
Real-time changes in brain activity during tibial nerve stimulation for overactive bladder: Evidence from functional near-infrared spectroscopy hype scanning
Authors: Li Xunhua , Fang Rui , Liao Limin , Li Xing
Published: April 2023

Purpose

To use functional near-infrared spectroscopy (fNIRS) to identify changes in brain activity during tibial nerve stimulation (TNS) in patients with overactive bladder (OAB) responsive to therapy.

Methods

Eighteen patients with refractory idiopathic OAB patients were recruited consecutively for this pilot study. At baseline, all patients completed 3 days voiding diary, Quality-of-Life score, Perception-of-Bladder-Condition, and Overactive-Bladder-Symptom score. Then 4 region-of-interest (ROI) fNIRS scans with 3 blocks were conducted for each patient. The block design was used: 60 s each for the task and rest periods and 3 to 5 repetitions of each period. A total of 360 s of data were collected. During the task period, patients used transcutaneous tibial nerve stimulation (TTNS) of 20-Hz frequency and a 0.2-millisecond pulse width and 30-milliamp stimulatory current to complete the experiment. The initial scan was obtained with a sham stimulation with an empty bladder, and a second was obtained with a verum stimulation with an empty bladder. Patients were given water till strong desire to void, and the third fNIRS scan with a verum stimulation was performed. The patients then needed to urinate since they could not tolerate the SDV condition for a long time. After a period of rest, the patients then were given water until they exhibited SDV state. The fourth scan with sham fNIRS scan in the SDV state was performed. NIRS_KIT software was used to analyze prefrontal activity, corrected by false discovery rate (FDR, p < 0.05). Statistical analyses were performed using GraphPad Prism software; p < 0.05 was considered significant.

Results

TTNS treatment was successful in 16 OAB patients and unsuccessful in 2. The 3 days voiding diary, Quality-of-Life score, Perception-of-Bladder-Condition, and Overactive-Bladder-Symptom score were significantly improved after TNS in the successfully treated group but not in the unsuccessfully treated group. The dorsolateral prefrontal cortex (DLPFC) (BA 9, Chapters 25 and 26) and the frontopolar area (FA) (BA 10, Chapters 35, 45, and 46) were significantly activated during TNS treatment with an empty bladder rather than with an SDV. Compared with the successfully treated group, the unsuccessfully treated group did not achieve statistical significance with an empty bladder and an SDV state.

Conclusion

fNIRS confirms that TNS influences brain activity in patients with OAB who respond to therapy. That may be the central mechanism of action of TNS.
Equity Investment Decisions of Operating Firms: Evidence from Property and Liability Insurers
Authors: Bae Sunghan , Liebenberg Andre P. , Liebenberg Ivonne A.
Published: April 2023

During the 2007–2009 financial crisis, almost 10% of Property and Liability (P&L) insurers completely liquidated their equity portfolios, and more than half of them never resumed equity market investments. In contrast, those P&L insurers that continued investing in equities after the crisis, increased their portfolio allocation substantially. To understand these findings, we develop and estimate models that explain P&L insurers’ dynamic equity investment decisions, in terms of firm, group, and market characteristics over the period 2002–2018. We study three different approaches to equity investments, a pure investment strategy, internal capital market contributions, and an outsourcing option and find that the factors driving the decision to invest in equities differ from those that explain the extent of their equity investments. Moreover, we find that while equity portfolio losses drive the decision to temporarily cease investments in equities, the decision to permanently exit equity markets is driven by both equity market losses and underwriting losses. These findings shed some light on the factors driving the demand for equity investments by operating firms.
Protection of Consumer Data on Digital Services in The Perspective of International Law and National Law
Authors:   Universitas Komputer Indonesia, Sari Febilita Wulan
Published: April 2023

The Covid-19 pandemic has implications for the community, namely the use of digital services to fulfill daily needs. This research aims to find the legal aspects of consumer data on digital services in the international law and national law, and how it is applied in Indonesia. This research uses analytical descriptive method with a juridical normative approach. The result of this research show that international law has various regulations in the form of hard law and soft law that regulate the protection of consumer data in digital service activities, including Article 17 of the International Covenant on Civil and Political Rights (ICCPR) 1966. Consumer protection in the national legal system is guaranteed by Article 4 Law Number 8 of 1999 concerning Consumer Protection, however, consumer data protection in digital services has not been optimally implemented because the law does not yet cover data protection. The guarantees stipulated in the Consumer Protection Law are information about goods and services, not information regarding consumer data. Data obtained from digital services is sometimes misused or transferred to other unauthorized parties. Encouraging the renewal of national provisions regarding consumer protection given the current developments in the digital era that make consumer data vulnerable.
The Establishment of Gender Quotas for Leadership Positions in Cooperatives to Promote the Principal of Voluntary and Open Membership
Authors: Ferraz Teixeira Marianna
Published: April 2023

The present work aims to understand whether the establishment of gender quotas for the composition of management positions in Brazilian and Portuguese cooperatives would have the power to fully promote the principle of voluntary and open membership. Therefore, an approach to the roles imposed by society on men and women and propagated by patriarchy is essential to understand why women created the feminist movement and how important it is to achieve equality. In addition, it is essential to understand the characteristics of cooperatives, as well as its first principle - voluntary and open membership - in order to verify the reasons why cooperatives become an ideal model for promoting gender equality. Despite this, in the Brazilian and Portuguese cases, the data show that there is a disparity between men and women from entry, but that it is more relevant when observing the managerial positions. Thus, based on this information and in view of the barriers that keep women away from leadership positions, understanding the conditions for implementing affirmative action such as quotas is essential to verify the possibility of its implementation in the case of cooperatives, in respect for the principles that govern them. In this way, the use of the focus-group methodology seeks to fill in the information collected by the doctrinal, legal and statistical study, based on the empirical analysis of the opinions of jurists and directors of cooperatives on the feasibility of the implementation and of alternatives capable of leading to parity.
Weaponizing Resilience: Women in the Trenches and Fringes of Pandemic Pedagogy
Authors: Schwartzman Roy , Simon Jenni
Published: April 2023

This study foregrounds the conflicting social pressures that women educators in the United States face in dealing with the ongoing COVID-19 pandemic in higher education. Narratives from three standpoints interweave to provide three perspectives on pandemic-informed practices that can build resilience as an inclusive rather than simply an individual process. The three points of view are: a mother in a non-tenure track teaching position who juggles caregiving duties; a male department head navigating how to energize allyship within a neoliberal educational system that suppresses acknowledgment and support of caretaking; and interactions among members of the Facebook group Pandemic Pedagogy, a global social media hub for educators adjusting to the pandemic’s impact. Collectively, these standpoints constitute a critical autoethnographic multilogue to deconstruct and remediate the systemic gender inequities exposed and exacerbated by the pandemic. The three perspectives converge on implementing feminist ethics of care as both a philosophical and practical foundation for constructively cultivating resilience at the personal, community, and institutional levels.
Softboys in the age of Millennial Masculinity
Authors: Muldoon Aaron
Published: April 2023

The last decade has witnessed the rise of a new type of Hollywood film star: the softboy. Actors including Timothée Chalamet and Harry Styles all appeal to the stereotypical characteristics of this type—young, skinny, fashionable, clean-shaven, quirky, gentle and emotionally intelligent. By analysing a sample of mainstream media articles on the softboy published between 2015 and 2023, the following paper seeks to deepen our understanding of this influential internet type and the dominant stereotype of masculinity he undermines—what R. W. Connell termed hegemonic masculinity. More specifically, this paper explores the extent to which the softboy can be understood as the product of an overlapping matrix of demand from gay male and straight female film and television audiences. Within this matrix, the softboy emerges as the result of a delicate balancing act in which he avoids presenting either as too straight, too gay or too masculine. He achieves this balance through a range of strategies involving clothing choices, film role choices, choices about sharing his personal life with the public and a carefully curated public persona. Considering the softboy from a cultural materialist perspective, this paper argues that the affected personality traits and designed sexual ambivalence of the softboy can be understood as a response not of men themselves but of the entertainment industry to both the increased demand for this type from straight female audiences in the wake of the #MeToo movement and the increasingly recognised demand for this type from gay male audiences. For straight women, the softboy appears to have superseded the stereotype of the muscled, bearded, deep-voiced or emotionally unavailable man in the hierarchy of desire precisely because he resists being easily framed as an aggressor. Meanwhile, either by playing gay roles in films or pandering to a stereotypically gay aesthetic or set of behaviours, these actors appeal simultaneously to the gay male audience. This analysis therefore attempts to construe contemporary changes in the nature of masculinity as it is represented by the rise of the softboy film star in terms of fundamental changes in the market of desire.
Red bilberry (Vaccinium vitis-idaed L.) microclonal reproduction
Authors:   Institute of Horticulture of the National Academy of Agrarian Sciences of Ukraine, Yaremko N.O. , Medvedieva T.V. ,   Institute of Horticulture of the National Academy of Agrarian Sciences of Ukraine, Udovychenko K.M. ,   Institute of Horticulture of the National Academy of Agrarian Sciences of Ukraine, Natalchuk T.A. ,   Institute of Horticulture of the National Academy of Agrarian Sciences of Ukraine, Zapolskyi Y.S. ,   Institute of Horticulture of the National Academy of Agrarian Sciences of Ukraine
Published: April 2023

The agents and their concentrations (0.1 % HgCl2 solution and 1 % and 2 % “Lizoformin 3000” solutions) influence on the efficiency and the explants initiation was researched in order to red bilberry cultivate under the conditions. All of them appeared effective for obtaining explants however for the further regeneration the use of the 0.1 % solution was optimum (61-85 % of the regenerated explants depending on the exposition). Such explants amount was maximum when utilizing 70 % of alcohol (30 sec.) and 0.1 % of the HgCl2 solution (4 min). Three nutritive media were studied for the effiecent red bilberry reproduction, namely: Anderson, Zimmerman and Broome and McCown as well as the best concentration was selected which provided the highest reproduction coefficient of the cultivar Runo Bielawskie. For instance, a nutritive medium and concentration were selected for the maximum explants proliferation in the conditions in vitro (the medium WPM with the addition of 2-iP in the concentration 5 mg/l – the reproduction coefficient being 3.8). Besides, the investigated factors effect on the reproduction coefficient was established statistically, the medium composition influence being the greatest one – 91 %. The rest of the factors did not effect this index considerably. The possibility of the simultaneous rooting and adaptation directly under the conditions ex vitro was proved with an effectivity of approximately 90 % that makes it possible to save costs when growing plants commercially. The efficient methods of the cv Runo Bielawskie reproduction were elaborated for the first time in Ukraine. Those methods may be applied for the studied crop drawing in the industrial numbers.
Modes of Callistephus chinensis (L.) nees seeds preservation
Authors:   Institute of Horticulture of the National Academy of Agrarian Sciences of Ukraine, Shevel L.O. , Rudnyk-Ivashchenko O.I. ,   Institute of Horticulture of the National Academy of Agrarian Sciences of Ukraine
Published: April 2023

The authors present the results of researching two Callistephus chinensis (L.) Nees varieties of different origin seeds storage regime for 36 months under different humidity and have established the positive effect on the seeds sowing qualities when storing them in low positive temperatures (+ 2 ... + 4 °С) (refrigerator) under a humidity of 8.0 % and 6.0 %. During the long-term storage in a humidity of 12.0 % the Callistephus chinensis (L.) Nees reduced dramatically the germination energy and laboratory germination, their values being zero. Therefore such storage regimes is critical for the studied crop. The three year investigations showed the advantage of storing the seeds under low positive temperatures as compared to the laboratory conditions (in banging). The varietal dependence of this economic trait was determined: the seeds of the cv Kniagynia of our own breeding have higher germination energy and laboratory germination in all the studied regimes as compared to the strain Birma of the German origin. This indicates a higher level of the inland variety plasticity. The results of the analysis have shown that it is inexpedient to store the Callistephus chinensis (L.) Nees seeds for 36 months under low positive temperatures and a humidity of 12.0 %.
Resource-saving elements of drip irrigation technology of intensive cherry plantations (Cerasus avium Moench.) in the conditions of the Southern Steppe of Ukraine
Authors:   M.F. Sydorenko Melitopol Research Station of Horticulture of the Institute of Horticulture, Maliuk T.V. , Kozlova L.V. ,   M.F. Sydorenko Melitopol Research Station of Horticulture of the Institute of Horticulture
Published: April 2023

The research is dedicated to establishing the parameters of the micro-irrigation regime in cherry orchards in the south of Ukraine using meteorological indicators and the amount of evapotranspiration as a basis for further determining the optimal irrigation regime. Field experiments were conducted in 2019-2020 on the lands of the M.F. Sydorenko Melitopol Research Station of Horticulture of the Institute of Horticulture, NAAS of Ukrain. In the investigation the following variants of the experiment are provided: a control variant – natural moistening, variants with the use of irrigation at pre-irrigation soil moisture level (PISML) of 70 % of least soil moisture (LSM) at different moisture layers of 0.4 m, 0.6 m, and 0.8 m, and variants with deficient irrigation at 100 %, 75 % and 50 % evapotranspiration compensation (ET0). As a result of research, it was established that the compensation of evapotranspiration (ET0) at the level of 75 % determines the maintenance of soil moisture in a layer of 0.6 m not lower than 67-70 % HB. The deviations of irrigation rates between this option and the PISML of 70 % LSM (0.6 m) do not exceed 6 % due to the increase in irrigation efficiency. Maintenance of 70 % LSM in the 0.4 m layer and at 50 % ET0 leads to a weakening of cherry production processes, which indicates the inconsistency of such a moisture regime with the biological requirements of cherry culture. The advantages of the irrigation regime for PISML 70 % LSM in a layer of 0.8 cm and for 100 % ET0 in terms of influence on cherry production processes were not revealed. At the same time, water consumption increases by 28-33 % due to a decrease in irrigation efficiency relative to compliance with this moisture regime in a layer of 0.6 m. The best indicators of irrigation efficiency were in the options of 75 % ET0 - 2.8 kg/m3 and with PISML 70 % LSM (0.6 m) – 2.2 kg/m3. Such data indicate the expediency of using the calculation method for determining the irrigation regime of cherry trees, as an alternative to the thermostatic-weight method.
Effectiveness of the biological agents application against apple (Malus domestica Borkh.) diseases
Authors:   Institute of Horticulture of the National Academy of Agrarian Sciences of Ukraine, Hradchenko S.I.
Published: April 2023

The author presents results of the two-year researching (2019-2020) the effectiveness of the biological means (PhytoHelp, MikoHelp, Kazumin 2L, RK, Cydox Pro, LS-1, Micro-Mineralis (universal) Plus, RK, Phytocid-r) against scab and apple fruit rot. The crop protection is limited almost as a whote to narrowing the spread and development of scab, all spraying was carried out the because of risk of the apple scab infection. The analysis of the weather conditions and instrumental monitoring of the epiphytic situation was conducted during April-August. There were 15 critical periods of the scab infection in 2019 and 2020. Respectively 5 and 4 sprays of the trees were made with experimental preparations. The analysis of the diseases spread and development the studing areas showed that all the preparations had a deterrent effect against apple scab, but higher results were obtained with the use of Kazumin, Fitohelp, MikoHelp and Fitocid-r. The development of this disease on the leaves as compared to the control variant decreased by nesrly 3-7 times( 1.4-6.1 % on the average). The efficiency of these preparations was 71-86 %. The development of scab when utilizeng LS 1 and Cydox Pro well as the fertilizers Micro-Mineralis Plus was 2.7-3 times less than in control, and their technical effectivity was 61-70 %. Casumin and Phytocid-r, which were 72-75 % effective, coped better with limiting the scab spread. With the application of Micro-Mineralis Plus worse the results were - only 41 %. The observations over fruit rot showed a low prevalence of the disease in all the experiment treatments. Nerely a few rotten fruits were defected. In the control variant without the use of where the fungicides, were fruit damage was 11 %, while in other variants this findex did not exceed 2 %, and the technical efficiency of the experimental preparations ranged from 79 to 100 %.
Facies associations and depositional environments of a mixed siliciclastic-carbonate marginal marine succession: The Lower Carnian (Upper Triassic) middle Charlie Lake Formation, Kobes-Blueberry area, British Columbia, Canada
Authors: Booker Simone , Hubbard Stephen , Rommens Chelsea , Zonneveld John-Paul
Published: April 2023

The Upper Triassic (Carnian) Charlie Lake Formation in northeastern British Columbia, Canada is a heterolithic mixed siliciclastic-carbonate succession of dolomite dolomitic siltstone, well-sorted sandstone, bioclastic sandstone, and anhydrite. This succession is unusual in that it records the only significant non-marine interval in the Triassic of the Western Canadian Sedimentary Basin. In the Kobes-Altares-Blueberry area, moderately abundant core are available through the middle members of the Charlie Lake Formation. All available core were analyzed in order to interpret the depositional setting of constituent members and identify reservoir quality lithofacies and horizons.

The middle Charlie Lake Formation in the Kobes-Altares-Blueberry area was deposited in an arid coastal setting. Sixteen lithofacies were identified and placed in three lithofacies assemblages and the latter characterize three depositional settings: coastal salina/playa, aeolian dune, and proximal marine ramps. The coastal salina/playa lithofacies assemblage is heterolithic, and is dominated by dolomitic and anhydritic facies. Depositional subenvironments include intertidal flat, ephemeral lagoon, shore proximal ephemeral lake, sabkha and supratidal paleosol. Potential reservoir lithofacies in this assemblage includes peloidal to stromatolitic dolomitic siltstone deposited in lagoonal and intertidal flat settings. The aeolian dune lithofacies assemblage preserves the movement of small, shore-proximal dunes and associated interdune successions. Well-sorted, fine-grained sandstone beds comprise the best reservoir lithofacies in this assemblage. The proximal marine ramp facies assemblage records several marine transgressions that punctuate the dominantly nonmarine/marginal marine Charlie Lake Formation. Bioclastic packstone, bioclastic sandstone and peloidal dolomitic siltstone to sandstone beds, all exhibit good porosity and are potential hydrocarbon reservoir units within this lithofacies assemblage.
Re-Label By Data Pattern Is All You Need For Knowledge Driven Deep Learning
Authors: Guo Tong
Published: April 2023

In industry deep learning application, we should fix the badcase by human evaluation after we achieve more than 95% accuracy at dev dataset. The badcase reason is from the wrong rule/knowledge of human labeling and will cause low accuracy under human evaluation. In this paper, we propose the pattern-based method to fix the badcase for industry application inference. We propose the pipeline to solve the problem and improve the accuracy of human evaluation. The experiment results verify our idea, which means label-edit is the method to implement controllable deep learning application.
Quantifying Impacts of the COVID-19 Pandemic on Ridership of CTA Rail and Bus Systems in Chicago
Authors:   University of Illinois Urbana-Champaign, Liu Yining , Osorio Jesus ,   University of Illinois Urbana-Champaign, Ouyang Yanfeng ,   University of Illinois Urbana-Champaign
Published: April 2023

This study’s research team conducted a comprehensive statistical analysis to help transit agencies better understand factors that may have contributed to transit ridership loss and the extent of its impacts. Building off ICT-IDOT project R27-SP45, they developed a series of statistical models for the Chicago Transit Authority’s rail and bus systems. Data-driven analysis of the COVID-19 pandemic’s impacts on CTA bus and rail ridership can help the Illinois Department of Transportation and Regional Transportation Authority, as well as other transit agencies, make policy decisions on planning resources and services during and after the pandemic. This study’s research team observed that most of the identified pandemic and socioeconomic factors, especially work occupancy rates, vaccination rates, discount programs, and crime rates, have affected over 80 to 90 percent of all CTA rail stations and bus lines. It is also observed that different population groups may react differently to policy decisions. The fare discount program, for example, may be most successful in attracting transit trips from the employed population in the health and retail industries. In particular, the temporal and spatial analyses show that work occupancy rates are crucial to answering most of the ridership loss at all of CTA’s bus lines and rail stations because workplace commute trips have driven a large proportion of CTA ridership. Therefore, transit ridership recovery may depend on individual industries’ remote work policies rather than city-wide quarantine executive orders. This could further suggest that transit agencies may need to collaborate closely with specific industry sectors to expedite the recovery of public transit ridership.
Retrospective Study of Pattern of Skull Fractures in Different Medicolegal Autopsies
Authors: G. Hema Latha  , M. Ramesh Babu  , B. Sugnan  , K. Lakshmi  , N. Dinesh Varma
Published: April 2023

Skull fractures occurred in RTAs, Assaults and other cases are the most common cause for hospitalization, disability, financial loss and death of the individual. Skull fractures are of various types i.e., linear, comminuted, depressed, hinge etc. Some of the skull fractures may cause rupture of dura mater and injury to brain matter thereby, causing permanent neurological damage and death. In this present study, we focused on the pattern of skull bone fractures involved in various manners like Accidental, Homicidal, Suicidal, also pattern of distribution among male and female, age wise distribution, time of death in a day, and also discussed about any other associated injuries that contributes to cause of death. 165(92%) skull fractures are observed in accidents, 141(78%) cases involve linear fracture. region wise distribution most commonly involved is base of skull region alone in 63(35%) cases commonly seen in fall from height cases, parieto-temporal and base of skull together 36(20%) cases seen in road traffic accidents, temporal and base of skull region 14(7.8%). In other associated injuries commonly involved intracranial haemorrhages and scalp contusions
Autopsy Study of Sudden Death Cases With Special Reference to Histopathological Changes in Heart
Authors: Mathipa S
Published: April 2023

Background: Sudden cardiac death and arrhythmia accounts for 15 – 20% of all deaths. Though Coronaryartery disease is the major cause of sudden deaths, diagnosis of other underlying causes is necessary. Hence weintended to analyze the various cardiac causes related to sudden deaths and the associated histopathologicalfindings of heart.Methods: Present study was an autopsy based cross sectional observational study conducted at MaduraiMedical College mortuary for a period of one year. 100 cases of sudden deaths were subjected to autopsy andhistopathological changes of heart were studied.Results: In the present study, majority of cases belonged to the age group of 40 - 60 years with male preponderance.In histopathological examination, atherosclerosis was the most common finding with involvement of left anteriordescending artery. Other findings include myocardial infarction, myocarditis, pericarditis and dysarrythmogenicventricular hypoplasia. Multiple cardiac lesions were noted in few cases.Conclusion: An accurate diagnosis of the underlying morbidity at risk of sudden death either at postmortemor in living patients and life threatening arrhythmias is the pre – requisite to adopt therapeutic and preventivestrategies.
An Incidental Autopsy Finding of Seminoma Testis in A Case of Suicidal Hanging – A Case Report
Authors: Rajalakshmi S  , Ragul Kumar D  , Vinoth K V
Published: April 2023

In the day-to-day practice of Forensic expert, hanging deaths is more commonly encountered. According toNational Crime Bureau Report of 2016, death due to hanging constitutes 46.2% of suicide in India. Hanging isdefined as a form of death which is produced by suspending the body with a ligature encircling the neck, theconstricting force being the weight of the body or a part of the body. Testicular cancers have been proven to causeparaneoplastic dermatomyositis and psychological depression in long term survivors. We report the case of a31-year-old man who was found hanging from a ceiling fan in his hostel room. He had a past medical historyof Schizophrenia & Depression for the past 5 years and a history of skin disease with lesions all over his body.Histopathological examination revealed Mixed Germ Cell Tumours – Seminoma Testis which was incidentallyfound during the autopsy.
Preliminary Emotional User Experience Model for Mobile Augmented Reality Application Design: A Kansei Engineering Approach
Authors: Nik Ahmad Nik Azlina , Abdullah Munaisyah , Mohd Lokman Anitawati , Suhaimi Ahmad Iqbal Hakim
Published: April 2023

The user experience, often known as UX, is the key factor in determining a product success and increase user’s acquisition. However, this field of research lacks conceptual and practical models to follow when designing pervasive technologies such as mobile augmented reality (MAR). To convey a pleasant UX, it is necessary to identify the contributing factor and the components that influence the enhancement of the MAR design. The findings of the study indicated that emotions are the main factor that drives the user’s perception and hence, their choice and pleasure. This paper presents a preliminary model for designing an emotional UX mobile augmented reality application with the use of Kansei engineering approach. Ultimately, this model will provide insight into the design fundamentals that influence the user experiences. The outcomes of this study will assist researchers and designers in shaping the emotional user experience design.
Fratura completa de tíbia em canino filhote tratado com tala: relato de caso
Authors:   Centro Universitário Ingá – Uningá, Maringá, PR, Brasil., Watanabe Paola Tieko Chiozzi , Marques Gabriel de Amorim ,   Centro Universitário Ingá – Uningá, Maringá, PR, Brasil., Casado Izabella Machado ,   Centro Universitário Ingá – Uningá, Maringá, PR, Brasil., Gonçalves Gabrieli  Junqueira ,   Centro Universitário Ingá – Uningá, Maringá, PR, Brasil., Lavelli Danielli Aparecida ,   Centro Universitário Ingá – Uningá, Maringá, PR, Brasil., Leal Leonardo Martins ,   Centro Universitário Ingá – Uningá, Maringá, PR, Brasil.
Published: April 2023

As fraturas são comuns na rotina de cães e de gatos. Seu diagnóstico se baseia na anamnese e exame físico ortopédico. Sua confirmação é feita pelo exame radiográfico. A osteossíntese é o tratamento de eleição na maioria dos casos, porém, em situações específicas, pode-se realizar o manejo das fraturas de tíbia com o uso de tala. Objetivou-se relatar o caso de um cão jovem com fratura completa de tíbia direita, que obteve rápida consolidação óssea somente com o uso de tala. Tal fato foi possível pois a fíbula direita não fraturou, o que possibilitou a manutenção do alinhamento interno do membro.
Hiperadrenocorticismo em cães: relato de caso
Authors:   Centro Universitário Ingá – Uningá, Maringá, PR, Brasil., Leite Juliana Thayna Soares , Liberato Adriely ,   Centro Universitário Ingá – Uningá, Maringá, PR, Brasil., Hungaro Gabriela ,   Centro Universitário Ingá – Uningá, Maringá, PR, Brasil., Fiorato Camila ,   Centro Universitário Ingá – Uningá, Maringá, PR, Brasil.
Published: April 2023

Hiperadrenocorticismo ou Síndrome de Cushing é uma endocrinopatia que está relacionada à produção excessiva de cortisol, no entanto, é comum acometer cães de meia idade a idosos. É considerada uma enfermidade silenciosa, pois, os pacientes possuem sinais clínicos inespecíficos, tais como poliúria, polidipsia, polifagia e alterações cutâneas, podendo desencadear doenças secundárias. O teste de supressão com Dexametasona é o de escolha para diagnosticar cães com o distúrbio. O presente trabalho tem como objetivo relatar o caso da cadela Lili, sem raça definida, 17 anos de idade, atendida na Clínica Veterinária Uningá e descrever como é a fisiopatogenia da doença.
Associação entre doença periodontal e doenças cardiovasculares: revisão de literatura
Authors:   Centro Universitário Ingá – Uningá, Maringá, PR, Brasil., Hildebrand Verônica , Coêlho Yuri Fernando Sampaio ,   Universidade Estadual de Maringá - UEM, Maringá, PR, Brasil.
Published: April 2023

A saúde oral é importante para a saúde geral e implica que dentes, gengiva e mucosas orais estejam íntegros e saudáveis. O objetivo é demonstrar, por meio de revisão, a relação entre a doença periodontal e doenças cardiovasculares. A metodologia adotada é uma revisão de literatura entre os anos de 2014 a 2022 nas bases de dados digitais. Os resultados evidenciam que existe uma associação entre saúde bucal e doenças sistêmicas, pois o desprovimento da higiene oral pode manifestar a doença periodontal. Em conclusão, pacientes com Doença Periodontal apresentam maior risco para Doenças Cardiovasculares, recomenda-se cuidados orais para prevenção de doenças sistêmicas.
Complicações associadas a exacerbações de asma na pediatria
Authors:   Centro Universitário Ingá – Uningá, Maringá, PR, Brasil., Cabral Karine Rodrigues , Calcagni Alexia Gimeni ,   Centro Universitário Ingá – Uningá, Maringá, PR, Brasil., Brambila Amanda Menezes ,   Centro Universitário Ingá – Uningá, Maringá, PR, Brasil., Vituri Bruna Bruder ,   Centro Universitário Ingá – Uningá, Maringá, PR, Brasil., Fumagalli Maria Gabriela ,   Centro Universitário Ingá – Uningá, Maringá, PR, Brasil.
Published: April 2023

A asma é uma das doenças crônicas mais comuns em Pediatria. Avaliamos o impacto causado nos pacientes através de artigos atualizados, em função da evolução para diversas complicações. Para tal, foi extraído informações diante das Diretrizes da Associação Brasileira de Alergia e Imunologia e Sociedade Brasileira de Pediatria, com o intuito de alertar sobre as dificuldades associadas a exacerbações de asma durante a infância. Além de estarem associadas a limitações, sendo capaz de atrapalhar o desenvolvimento.
Numerically Optimized Effects of Contact Time Factor of Pulverized and Modified Bio-Adsorbents on Nitrogen Removal Rates in Industrial Wastewater
Authors: Ossai Blessing Josephine , Iweriolor Sunday , Odeworitse Eyide
Published: April 2023

This study investigated the effect of contact time of two agricultural wastes (cassava peels and ripe plantain peels) used as bio-adsorbents that were modified with base and acids to ascertain their ability to absorb nitrogenous compounds from hospital and abattoir wastewater. The absorbents were prepared using standard procedures into powdered forms and a portion was modified with acid and base respectively. Fourier Infrared spectroscopy was used on the prepared absorbents to determine the organic and functional groups present. Each modified bio-adsorbents was used to inoculate each of the 250 ml flasks containing the wastewater sample. Contact was allowed to be made for 14 hours and the nitrogen removal rate was measured and recorded. The Nitrogen concentration in the wastewater was determined using Ultra-violent spectroscopy. Response surface optimization was used to investigate the effect of contact time on the nitrogen removal rate. Models were generated to analyze the interactions between variables at optimum conditions. The results showed that the bio-adsorbents have the ability to remove nitrogen from wastewater. The nitrogen percentage removal recorded was 57%, 81%, and 77%, 55%, 91% ,and 78% respectively. The R2 from ANOVA was seen to be 96.5%, 97.9%, 97.9%, 98.2%, and 99.7%, and 97.9% repectively. Experimental results were best fitted into linear and quadratic polynomial models. The optimum conditions having desirability of 0.964 showed that the time of 13.558 hrs. The values obtained are a good indicator that the bio adsorbents used in this should be considered by the chemical industries in the process of absorbent design and production.