bluuebunny/crossref_metadata_2025 huggingface dataset:
A modular approach to tuning the charge transfer properties of photoluminescent quinine analogues.
Authors: Watson Joseph , Pollard Ruth , Etherington Marc , Knowles Jonathan
Published: April 2023

We have shown that Pd-catalysed cascade processes provide molecular access to rigid quinoline-containing tetracylic amines. This enables fine-tuning of the through-space charge transfer (TSCT) state formation by variation of both N-aryl distance and quinoline substitution. It was observed that decreasing the N-aryl distance enhanced the formation of the TSCT species giving control over emission colour and photoluminescence quantum yield. Methoxylation of the quinoline unit decreases the propensity of TSCT formation. This systematic study provides great insight for TSCT formation with impact on further understanding dimeric, excimeric and exciplex species.
Chalcogen-Substituted Carbenes: A Density Functional Study of Structure, Stability, and Donor Ability
Authors: Ritch Jamie
Published: April 2023

Chalcogen-substituted carbenes are examined computationally using density functional theory. Several approaches are used to assess the stability and reactivity of chalcogenazol-2-ylidene carbenes (NEHCs; E = O, S, Se, Te). The known unsaturated species 1,3-dimethylimidazol-2-ylidene is studied at the same level of theory as the NEHC molecules, as a reference. Electronic structures, stability towards dimerization, and ligand properties are discussed. The results highlight the NEHCs as potentially valuable ancillary ligands for stabilizing low-valent metals or paramagnetic main group molecules. A simple, effective computational method for evaluating sigma donor ability and pi acidity of carbenes is presented.
Role of the energy offset on the charge photogeneration and voltage loss of nonfullerene acceptor-based organic solar cells
Authors: Tamai Yasunari , Shirouchi Rei , Saito Toshiharu , Kohzuki Kazuki , Natsuda Shin-ichiro
Published: April 2023

The trade-off between the short-circuit current density (JSC) and open-circuit voltage (VOC) has been one of the largest challenges in improving the power conversion efficiencies (PCEs) of organic solar cells (OSCs). Although energy offset between the optical bandgap and the charge transfer (CT) states should be maintained as small as possible to improve VOC, a very small energy offset typically leads to degradation of JSC, even when novel nonfullerene acceptors (NFAs), such as Y6, are used. Therefore, understanding the limit to what extent the energy offset can be minimized and the underlying physics behind the trade-off relationship is important to optimize the design of new materials and further improve the PCEs. This study provides a threshold energy that can ensure high charge photogeneration quantum efficiencies for Y-series NFA-based OSCs and discusses the role of the energy offset in device performances. We found that an insufficient energy offset led to not only slow hole transfer at the donor:acceptor interfaces, but also inefficient long-range spatial dissociation of the CT states and degradation of the fill factor (FF). This study also discusses the interplay of the energy levels of two NFAs that constitute ternary blend OSCs. We found that combining two NFAs enables to reduce the voltage loss, while maintaining a high charge photogeneration quantum efficiency. Our findings highlight the importance of overcoming the trade-off between FF and VOC for further improving the PCE.
Cultural landscape zoning of Ukraine
Authors: Polyvach Kateryna
Published: April 2023

Formulation of the problem. Nowadays in Ukraine there is a significant gap in the application of cultural-landscape approach and the lack of cultural and landscape zoning (CLZ) at different taxonomic levels, as one of the fundamental stages in the protection and preservation of cultural and natural heritage, which is recognized in a number of international documents by the world community.

The purpose of the article. The purpose of this study is to develop methodological approaches to CLZ in Ukraine.

Analysis of recent research and publications. The study and analysis of the experience of differentiation and zoning of different level territories on the basis of cultural and landscape approach in some European countries showed the crucial role of CLZ in studying cultural landscapes and planning management actions for their protection, conservation and use.

Methodology and results. The overall purpose of CLZ was to identify, define and differentiate integral natural and cultural systemic territorial formations of different levels, which form a set of interconnected cultural landscapes in a given area. The main factors of cultural-landscape differentiation of Ukraine at the macro level were natural-geographical, ethnographic, linguistic, historical-geographical, historical-political and administrative-territorial features and features of spatial localization and concentration of natural and cultural heritage - immovable and intangible. The information base for conducting the CLZ were researches that reflects the territorial differentiation of Ukraine by these groups of features and has developed appropriate zoning schemes with their cartographic implementation. The taxonomic system of the country's CLZ has been developed. It consists of two levels: 14 cultural-landscape regions and 52 cultural-landscape macro-districts; 26 cultural and landscape regions have been identified as a separate taxon, outside of the hierarchy, according to the administrative-territorial division of the country. The most important result of the study – the map "Cultural-landscape zoning of Ukraine", became one of the key topics of the electronic atlas "Population of Ukraine and its natural and cultural heritage". The development of the atlas was completed in 2020 by the Institute of Geography of NASU.

Scientific novelty and practical significance. For the first time in Ukraine, CLZ has been developed at the macro level, thus starting to fill a gap of the absence of domestic developments of this kind. The study identified proposals on the main directions of development and practical application of CLZ in the field of protection and preservation of cultural and natural heritage through inclusion in the systems of national and regional strategy, spatial development planning, research on integrated study of territory, mapping and development of CLZ regions and administrative districts, etc.
Probabilistic-forecasting method for determination of low flow discharge of Pivdennyi Buh, Black Sea area, and Lower Dnieper rivers
Authors: Shakirzanova Zhannetta , Ovcharuk Valeriya , Dokus Anhelina , Kushchenko Liliia , Tymko Olena
Published: April 2023

The aim of the study is to substantiate the probabilistic-forecasting method for forecasting the low flow discharge and its implementation for the Pivdennyi Buh, Black Sea area and Lower Dnieper rivers, taking into account climatic patterns of precipitation distribution and establishing probabilistic characteristics of low flow discharge in multi-year period. The study area is in a zone of significant risk due to the shortage of water resources, the formation of extremely low runoff in the dry flow period, which requires its definition and forecasting. The methodological basis of forecasts is to solve the equation in determining the components of the low flow of rivers by constructing regional dependences for forecasting the average decade summer-autumn low flow from previous water discharge (in runoff modules), establishing their probabilities water discharge for a number of intakes. Results. The paper substantiates the probabilistic-forecasting method for forecasting low flow discharge (in summer, autumn and winter periods) based on the construction of regional dependences of average decadal runoff modules on previous water discharge for groups of basins of studied rivers taking into account climatic dependences of precipitation distribution in the territory and the establishment of probabilistic characteristics of the low flow water discharge in a multi-year period. The methodology of territorial short-term forecasts of average decade water discharge of low flow of summer, autumn and winter river runoff is assessed as satisfactory with a margin of error of 70 % to 97 %, with a number of members of more than 500 points. To determine the cumulative probability of the forecast values of the average decade water discharge of the summer, autumn and winter dry weather flow, the empirical distribution of the average monthly water discharge in the limited seasons, which are generalized in the basins of the studied rivers of Ukraine, is established. Scientific novelty. For the first time for the zone of insufficient natural water content of rivers the method of territorial forecasts of low flow discharge, determination of their probability of occurrence in a multi-year period and cartographic representation of prognostic values have been developed and practically implemented. The practical importance is the use of forecast modules maps of low flow for spatial monitoring and assessment of low water levels on rivers in the whole region, including ungauged rivers, and their probabilistic characteristics – to assess the possible occurrence of low runoff, even when it reaches values close to the environmental runoff, which are critical for the functioning of the river ecosystem.
Effect of oil contamination on the course of changes in chernozem properties and phytotoxicity
Authors: Krainiukov Olekcii , Miroshnychenko Inna , Sіabruk Olesia , Hladkikh Yevheniia
Published: April 2023

Introduction. The consumption of hydrocarbons in the world is steadily growing with the response to the progress of civilization. It is accompanied by the continuous flow of hydrocarbon pollutants into the environment. Soil pollution with oil attracts special attention, because the soil is a key element in the trophic chain of toxicants in the human body.

Purpose. Investigate changes in the properties (physicochemical, agrochemical and biological) of chernozem soils and its phytotoxicity at different levels of oil pollution for further use of the parameters of these indicators during soil monitoring.

Research methods. The research was conducted during 2019-2021 in the conditions of the Left-Bank Forest-Steppe of Ukraine in a field small-plot experiment on Chernozem Luvic with the frequency of observations on diagnostic indicators at 1 month, 6, 12 and 24 months. The scheme of the experiment provided for soil contamination with oil in the amount of 0.4 l/m2, 1.6 l/m2, 6.4 l/m2, 25.6 l/m2.

Results. The rate of biodegradation of oil products for different levels of pollution of Chernozem Luvic was determined - with insignificant pollution, self-purification of the soil is characterized by a faster course than with medium and strong, within 24 months the content of hydrocarbons decreased by 85-87% and 60-64%, respectively. One of the important mechanisms for the loss of hydrocarbons from the soil surface is microbiological decomposition, studies have shown that in the oil concentration range of 6.4-24.6 l/m2, there was a significant increase in the intensity of carbon dioxide release from the soil, which is 60% higher than in the control option, this indicates the intensification of the processes of its biodegradation. Studies of changes in such diagnostic indicators as soil pH, the content of water-soluble potassium and sodium show a less significant influence of the factor of soil pollution with oil compared to the influence of the time factor. However, these indicators are of great diagnostic value in the process of monitoring oil-contaminated soils and remediation, since the most optimal parameters of these indicators determine the suitability of soils for plant growth and microbial life. Studies of phytotoxicity of oil-contaminated soil have shown the negative impact of oil on seed germination in the field condition.

Conclusions. The research results indicate a gradual self-purification of the soil from petroleum hydrocarbons during the observation period. The obtained regularities of the dynamics of changes in the studied parameters will be used to improve the scientific and methodological support for monitoring soils affected by oil pollution.
Interpreting mereotopological connection
Authors: Gan Nat
Published: April 2023

This paper examines ten possible topological interpretations of connection and for each interpretation, identifies sufficient conditions under which a significant class of topological spaces provides models of General Extensional Mereotopology with Closure Conditions (GEMTC) in which some key mereotopological ideas align with their topological analogues. In particular, there is an interpretation under which the non-empty sets of any symmetric topology are a model of GEMTC with alignment between the mereotopological and topological definitions of (self-)connection, open and closed entities, interior, exterior, closure, and boundary.
Geometry of Relevant Implication II
Authors: Urquhart Alasdair
Published: April 2023

This note extends earlier results on geometrical interpretations of the logic KR to prove some additional results, including a simple undecidability proof for the four-variable fragment of KR.
Daylight Control and Window Design In Apartments
Authors:   , Doyle Mackenzie
Published: April 2023

The window design in New Zealand apartments can be limited to their design qualities as they are required to meet the minimum code from Acceptable Solutions G7/AS2. The windows produced under the Building Code standard are not necessarily designed and positioned correctly to optimise light in terms of daylight distribution (Boubekri, 2014). Nor are they designed to provide liveable and habitable qualities where the occupants can sit, stand, or lie down. This can have negative implications on an occupant’s well-being (Bevins III et al., 2012, p. 31).

The aim of this thesis is to design windows that create habitable spaces and manipulate light rather than just being an opening in a wall. 

This paper uses a research-through-design approach. Literature and precedent studies have been analysed to determine the importance of good quality window design that the occupants can inhabit. The strategy of this research is to address the current problem with the window design within the Natural Light Acceptable Solutions G7/AS method in New Zealand and compare it with new enhanced habitable window designs.

To understand the complexity of this, an apartment building has been designed as a testing framework. This framework is used to test quantitative and qualitative metrics. This framework also allowed testing against the Acceptable Solutions baseline method G7/AS and several new window designs. The baseline window solution was established and then compared against a new set of windows that have been designed for the potential to have better habitable qualities. The key simulation metric used is the Daylight Autonomy (DA), modelled through Honeybee heat maps.

The first concept set of windows provided good daylight distribution throughout the building. They also over-provided with excess daylight. Revising the window sizes provided for a more precise window design for each room. The size of the glazing changed, and the overall percentage of wall-to-glazing area decreased.

The Building Code Acceptable Solutions method designed windows with no habitable qualities. They were not designed to tilt towards the sun or respond to orientation and lacked important qualities that could improve the well-being and liveability of the occupants. Habitability starts when a window can provide more than just daylight provision. Designing windows that provide habitability qualities have been found to produce good quality daylight distribution, as well as provide a place where the occupants can sit, stand, lay down or put potted plants.

This thesis successfully revealed that new windows could be designed to meet the New Zealand Building Code and provide more habitable qualities, and are superior for the occupant’s well-being. 
Konsiderans dalam Estetik Karya Fotografi “Manekung”
Authors: Panji Yulli Adam , Akhmad Imam
Published: April 2023

Artikel ilmiah ini memaparkan penelitian dan penciptaan karya seni fotografi manekung. Penamaan tema “manekung” dalam karya fotografi ini diambil dari konsep bahwa karya fotografi dapat dijadikan sebagai media dari meditasi (manekung). Penelitian dan penciptaan memakai pendekatan Practice-led Research yang dilakukan melalui studi praktik di lapangan yang bertujuan menyajikan kreativitas di bidang fotografi. Adapun karya yang dihasilkan menyajikan kebaruan dalam aliran ekspresi fotografi. Tahapan metode penciptaan ini memakai tiga tahapan yaitu sebagai berikut. 1) Praproduksi: penyiapan alat dan bahan, observasi dan kajian pustaka, proses penemuan ide, dan proses meditasi. 2) Tahap Produksi: imaji abstrak dan konkret, eksplorasi objek, eksperimentasi bahan, pematangan konsep, dan meditasi. 3) Tahap Ketiga penyajian karya: pengemasan dan pameran fotografi. Penelitian dan penciptaan karya menghasilkan tujuh belas karya meditasi fotografi berbagai ukuran yang dikemas dengan frame, disajikan pada pameran dengan suasana yang dibangun pada ketenangan dan keheningan.

Kata kunci: meditasi, manekung, fotografi, penciptaan, ekspresi, karya
Kenyamanan Sirkulasi Bangunan Kampus Berdasarkan Persepsi Pengguna (Studi Kasus Gedung E ITERA)
Authors: Satria Widi Dwi , Sinaga Puspita Sari , Wibowo Yoga Hadi
Published: April 2023

Institut Teknologi Sumatera (ITERA) merupakan salah satu institut teknologi yang berada di Pulau Sumatera. ITERA haruslah menyediakan fasilitas gedung yang memadai untuk menunjang kegiatan perkuliahan. Salah satu gedung perkuliahan yang disediakan oleh ITERA yakni Gedung E. Penelitian ini bertujuan untuk mengetahui persepsi mahasiswa terhadap kenyamanan sirkulasi Gedung E ITERA. Penelitian ini dilakukan secara kualitatif dengan pendekatan observasi dan penilaian kuesioner terhadap 50 responden dengan tujuan untuk memperdalam analisa yang dilakukan antara kondisi lapangan dengan persepsi pengguna terhadap suatu fenomena yang terjadi secara apa adanya. Hasil penelitian menunjukkan lebih dari 50% sirkulasi pada area ruang dalam Gedung E ITERA masih dapat dikategorikan nyaman. Adapun berdasarkan hasil kusesioner tentang kelayakan, kesesuaian, kenyamanan, kebisingan, dan keamanan gedung E menunjujukkan hasil yang masih dirasakan nyaman oleh penghuni. Beberapa hal yang masih dirasa kurang oleh pengguna Gedung E adalah tingkat kesesuaian ruang kelas yang dinilai kurang oleh pengguna.
STUDY OF LAYOUT, CIRCULATION, AND ORNAMENTS IN TEMPLE BUILDING (Case Study: Satya Budhi Temple, Bandung)
Authors: Wardhani Mustika , Praseta Aldo , Ramadhan Salman , Cahyowati Thinka S , Achsanta Debby N
Published: April 2023

The existence of temple buildings in Indonesia is part of the acculturation of Chinese culture that develops time by time. The temple, which is functionally used as a place of worship, has a unique role in historical developments in Indonesia, especially in Bandung. Satya Budhi Temple is one of the temple buildings in Bandung, which is more than 50 years old and is the oldest temple in this city. This building is part of the cultural heritage of Bandung, whose sustainability should be studied in terms of architecture. This research seeks to dig deeper into how the temple building's layout, circulation flow, and ornaments manifest the values of the Chinese philosophy of life, society, and culture. The research method uses a qualitative descriptive method accompanied by sketches of the elements forming space and circulation. The findings in this study show that the architecture of the temple has a distinctive spatial layout accompanied by a linear circulation which represents the journey towards the profane-sacred transition of humans towards God. From the findings of this study, it is hoped that cultural heritage buildings with a typology of worship places can continue to be preserved through preservation and revitalization efforts so that their historical value is well maintained.Keywords: Layout, Circulation flow, Ornament, Temple building, Cultural heritage building
СИНТЕЗ, СТРОЕНИЕ И МАГНИТНЫЕ СВОЙСТВА ПОЛИМЕРНЫХ КОМПЛЕКСОВ Cu(hfac)2 С ЦИАНОФЕНИЛЗАМЕЩЕННЫМИ НИТРОКСИЛАМИ
Authors: Артюхова Н.А. , Заргарова Л.В. , Романенко Г.В. , Богомяков А.С. , Овчаренко В.И.
Published: April 2023

Получены спироциклопентильные производные цианофенил-замещенных нитроксильных радикалов 2-(4'-цианофенил)-4,5-бис(спироциклопентил)-4,5-дигидро-1Н-имидазол-3-оксид-1-оксил (NN) и соответствующий иминонитроксил – 2-(4'-цианофенил)-4,5-бис(спироциклопентил)-4,5-дигидро-1Н-имидазол-1-оксил (IN), исследовано их строение и магнитные свойства. При взаимодействии нитроксилов IN и NN с бис(гексафторацетилацетонато)меди(II) [Cu(hfac)2] образуются гетероспиновые цепочечно-полимерные или слоистые комплексы {[Cu(hfac)2]2(IN)}, {[Cu(hfac)2]3(NN)2} и {[Cu(hfac)2]3(NN)2}∙C7H16. Установлено, что слоистый {[Cu(hfac)2]3(NN)2}·C7H16 переходит в магнитоупорядоченное состояние при гелиевых температурах и представляет собой мягкий ферромагнетик.
Photochromic and Electrochromic Study of Schiff Bases Containing Pyrazolone and Anthracene unit
Authors: Surati P.R.
Published: April 2023

New Schiff bases 4-((anthracen-2-ylimino) methyl)-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one (1C), 4-(1-(anthracen-2-ylimino)ethyl)-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one (2C) and 4-((anthracen-2-ylimino)(phenyl)methyl)-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one (3C) were synthesised and characterized by elemental analyses, LC-MS, FTIR and 1H-NMR spectra. The photochromic property of the synthesised compound investigated under 365 nm UV-light irradiation, which can be observed with solution and solid state absorption spectra. The kinetics study show that the photochromic reaction is of peusdo first order. The photoisomerization is due to photoinduced intramolecular hydrogen bond, which results in enol to keto transformation. The electrochromic properties in solution were checked using cyclic voltammetric(CV) results in acetonitrile solvent. The CV result indicates that all three compounds show electrochromic behaviour in solution state. Further frontier molecular orbitals (FMOs) of all molecule in keto and enol form calculated using B3LYP/6-31G* which also relatable with experimental data.
SYSTEM FOR CYBER SECURITY EVENTS CORRELATION AND INCIDENT MANAGEMENT IN CRITICAL INFRASTRUCTURE OBJECTS
Authors: Gnatyuk Sergiy , Berdibayev Rat , Sydorenko Viktoriia , Zhyharevych Oksana , Smirnova Tetiana
Published: April 2023

Modern information infrastructure consists of a large number of systems and components that require constant monitoring and control. To identify, analyze and eliminate possible cyber threats, it is recommended to use a single common solution - the so-called SIEM systems. SIEM technology collects event log data, detects unusual activity through real-time analysis, identifies threats, generates alerts, and suggests appropriate action scenarios. Today, the number and quality of SIEM systems has grown significantly, and the latest technologies of artificial intelligence, the Internet of Things, and cloud technologies are used to ensure fast and effective detection of threats. Thus, the work carried out a study of modern SIEM systems, their functionality, basic principles of operation, as well as a comparative analysis of their capabilities and differences, advantages and disadvantages of use. In addition, a universal system of event correlation and management of cyber security incidents at critical infrastructure facilities was developed and experimentally investigated. Models of the operation of the hybrid security data storage have been developed, which allow the indexing service to access external data storages, to perform scaling when the volume of data increases, to ensure high search speed, etc. Models, methods and algorithms for the operation of a distributed data bus have been developed, which allow for high speed processing of large flows of information, minimal delays in data processing, high resistance to failures, flexibility and expandability of storage. The proposed system is designed to solve a number of current cyber security problems and meets the main requirements of international standards and best global practices regarding the creation of cyber incident management systems.
METHOD OF FORMING ASSOCIATIVE RULES FROM THE SIEM DATABASE BASED ON FUZZY SET THEORY AND LINGUISTIC TERMS
Authors: Subach Ihor , Mykytiuk Artem
Published: April 2023

The article presents a method of forming fuzzy associative rules with weighted attributes from the database (DB) of the SIEM to supplement its knowledge base (KB) in order to more effectively detect cyber incidents that occur during the operation of special information and communication systems (SICS). The problems that reduce the effectiveness of the application of existing methods for solving the problem of forming associative rules based on the analysis of information located in the database of cyber protection systems are considered. An analysis of publications devoted to methods in which attempts were made to eliminate these problems was made. The basic idea of eliminating the shortcomings inherent in known methods is formulated, which consists in finding a compromise between reducing the time of the computing algorithm that implements the method in practice and reducing information losses as a result of its operation. An improved method of finding associative rules from SIEM databases is proposed, which is based on the theory of fuzzy sets and linguistic terms. The problem of finding fuzzy associative rules with weighted attributes is formulated. The mathematical apparatus that forms the basis of the implementation of the method is given. An algorithm for finding frequent sets of elements, including the values of the signs of cyber incidents and the classes to which they belong, is proposed, which implements the first stage of the proposed method. The peculiarities of the structure of the test data sets used for training and testing of cyber protection systems were analyzed, and based on its results, a conclusion was drawn about the possibility of improving the considered algorithm. A graphic illustration of the idea of improving the algorithm for finding frequent sets of elements is given and the essence of its improvement is described. An improved algorithm for finding frequent sets of elements of the considered method is proposed and its main advantages are given.
Zumbo'nun madde tepki sürecine yönelik eleştirel bakış açısıyla Türkçeyi Ölçme ve değerlendirmede yeni yaklaşımlar
Authors: GÖKTENTÜRK Talha , SAĞLAM Mehmet Hilmi , ZUMBO Bruno D.
Published: April 2023

Ana dili olarak Türkçenin ölçülmesi ve değerlendirilmesi maddenin kendisi ve maddeye yönelik katılımcı tepkilerine odaklı bir yaklaşımla sürmektedir. 21. yüzyılda Türkçenin ölçülmesi ise MEB ve ÖSYM öncülüğündeki testler yoluyla gerçekleşmekte ve aynı yaklaşımla paydaşlar tarafından yürütülmektedir. Bununla beraber Dünya’da maddeye tepki sürecinin ekolojik arka planının araştırılması ehemmiyetini giderek artırmaktadır. Madde tepki sürecinde madde ile karşılaşan katılımcı, tepkisinde arka plandaki kompleks bir ekolojik örüntüden etkilenmektedir. Dolayısıyla ilgili örüntünün geçerlilik araştırmalarına dâhil edilmemesi tablonun sınırlı görülebilmesine ve ölçme sonuçlarının eksik yorumlanmasına neden olmaktadır. Madde yanlılığı araştırmalarının mühim bir parçası olan diferansiyel madde fonksiyonunu belirlemeye yönelik çalışmalar bu noktada umut vermektedir. Buradan hareketle Türkçenin ana dili olarak ölçülmesindeki kısıtlı yaklaşımlara da karşılık 3 adımda bu çalışma şekillendirilmiştir. Birinci adımda ana dili olarak Türkçenin ölçülmesi ve değerlendirilmesine yönelik bir çerçeve sunulmuştur. İkinci adımda madde tepki sürecinin ekolojisi tartışılmıştır. Üçüncü adımda kompleks arka planın keşfi için diferansiyel madde fonksiyonu araştırmalarından potansiyel bir çözüm olarak Zumbo ve diğerleri (2015) tarafından geliştirilen ekolojik model tanıtılmıştır. Son aşamada ise kurum bazında MEB ve ÖSYM başta olmak üzere madde yazarları, araştırmacılar ve politika yapıcılar için tavsiye ve teklifler sıralanmıştır. Tartışmanın çıkarımından hareketle ana dili olarak Türkçenin ölçülmesi ve değerlendirilmesinde ekolojik yaklaşımın ve ekolojik modelin geçerlilik araştırmaları için büyük bir potansiyel taşıdığı söylenebilir. Dolayısıyla Türkiye’nin ölçme ihtiyaçlarına uygun olarak ekoloji tabanlı bir perspektifin Türkçenin ana dilinde ölçülmesine adapte edilmesi gerekmektedir. Böylece Türkçe dersi öğretim programının ölçmeye ve değerlendirmeye yönelik yaklaşım ihtiyacının karşılanması mümkün olacaktır.
TRT Çocuk Kitaplık örneğinde kitap kahramanlarına atfedilen mesleklerin karşılaştırılması
Authors: YOLASIĞMAZOĞLU Hülya
Published: April 2023

Bu araştırmada, kitap kahramanlarına atfedilen mesleklerin karşılaştırılması amaçlanmıştır. Bu amaç ile, TRT Çocuk Kitaplık bünyesinde yer alan eserlerden ölçüt örnekleme yolu ile seçilen 202 çocuk kitabı incelenmiş ve kitaplarda yer alan kahramanlara atfedilen mesleklerin kitap kahramanlarının cinsiyetlerine, kitap yazarlarının cinsiyetlerine ve kitap yazarlarının yerli ya da yabancı olması durumuna göre farklılık gösterip göstermediği sorularına yanıt aranmıştır. Betimsel tarama modelinde tasarlanan bu araştırmada veriler, doküman inceleme yöntemi ile elde edilmiştir. Elde edilen verilerin çözümlenmesinde öncelikle, betimleyici istatistiklerden yüzde ve frekans analizi, ardından ki-kare testi kullanılarak hesaplamalar yapılmış; elde edilen sonuçlar tablolar hâlinde sunulmuş ve yorumlanmıştır. Elde edilen sonuçlara göre: araştırmaya konu kitaplarda yer alan kahramanlara atfedilen meslekler, ilgili kahramanın cinsiyetine göre anlamlı yönde farklılık göstermektedir. Cinsiyeti kadın olan kahramanlara en çok ‘Profesyonel Meslek Mensupları’ grubu altında yer alan meslekler, cinsiyeti erkek olan kahramanlara ise en çok ‘Yönetici’ ile ‘Hizmet ve Satış Elemanları’ grubu altında incelenen meslekler atfedilmiştir. Bunun ile birlikte, araştırmaya konu kitaplarda yer alan kahramanlara atfedilen meslekler, kitap yazarlarının cinsiyetine ve de yerli ya da yabancı olması durumuna bağlı olarak farklılık göstermemektedir.
Basic principles of genome editing
Authors: Smirnihina Svetlana , Anuchina Arina , Kucev Sergey
Published: April 2023

This teaching aid is intended for students to master the basic stages of genomic editing using CRISPR-Cas9 technology and is compiled in accordance with the requirements of the Federal State Educational Standard of Higher Education in the specialties 31.08.30 "Genetics" and 31.08.06 "Laboratory genetics", as well as taking into account the professional standards of doctors the above specialties; scientific specialties 1.5.7. "genetics" and 3.3.8. "clinical laboratory diagnostics" in the preparation of scientific and pedagogical staff in graduate school
The main purpose of this manual is to introduce students to the methods of genome editing, gain knowledge about the application of genomic editing for the treatment of hereditary diseases, acquire skills in the design of tools for genomic editing and assess the consequences of genomic editing at the level of a changed DNA locus.
The manual is intended for residents in the above specialties, graduate students in scientific specialties 1.5.7. "genetics", 3.3.8. "clinical laboratory diagnostics", as well as for geneticists, laboratory geneticists and specialists in the field of clinical laboratory diagnostics when training them under advanced training programs.
Published by the decision of the educational and methodological commission of the Institute of Higher and Additional Professional Education of the Federal State Budgetary Scientific Institution “Medical Genetic Research Center named after Academician N.P. Bochkov dated 23.09.2022
Buket Uzuner’in Gelibolu Romanı Örneğinde 1980 Sonrası Türk Romanında Kentli Milliyetçi Tutum
Authors: SOLAK Ömer
Published: April 2023

Kentleşme, tüm dünyada toplumu ve dolayısıyla edebiyatı derinden etkilemiş bir süreçtir. Beraberinde getirdiği sosyolojik olgulardan biri de kentli milliyetçilik‘tir. Kavram, ortaya çıktığından beri sosyoloji, demografi ve ideoloji arakesitinde pek çok çalışmaya konu olmuştur. Öte yandan Türk toplumu da benzeri süreçleri yaşamış ve bu süreçler edebiyata yansımıştır.

Bu çalışmada kentli orta sınıf değerleri ve burjuvazinin periferiye bakışı bir roman örneğinde ele alınmıştır. Buket Uzuner’in olay örgüsü iki farklı zaman katmanı içinde geçen Gelibolu romanı (1999) betimsel analiz yöntemiyle incelenmiştir. Romanın olay örgüsünün birinci katmanının karakterleri doğu-batı çatışmasının temsilcileridir. İkinci katmanın karakterleri de merkez-taşra çatışmasının taraflarıdır. Yazar, romanın biraz Doğulu, biraz Batılı, biraz Balkanlı, biraz Kafkaslı, ama en çok Akdenizli olmayı önemseyen karakterleri üzerinden kentli üst kültürcü milliyetçiliği savunur. Dolayısıyla roman, hem 1960’ların Mavi Anadoluculuğunun bir devamı, hem de seküler milliyetçi ve Atatürkçü perspektifin bir yeniden üretimi şeklinde okunabilir.

Çalışmanın amacı, ele alınan roman örneğinde kentli milliyetçilik olgusunun anılan dönemin edebiyatına nasıl yansıdığını ortaya koymaktır. Öte yandan edebiyat ve sosyoloji arakesitindeki bu olguyu Türk romanları üzerinde ele ala alan herhangi bir çalışmanın bulunmaması çalışmanın önemini ortaya koymaktır. Öte yandan makale türünün sınırları gereği, ele alınan döneme dair yönelimleri tek bir roman ve bu romana uygulanan bir çözümleme yönteminin sağladığı bulgular üzerinden genellendiğini de ifade etmek gerekir
School Library eBook Providers and Spanish Language Equity:
Authors: Paganelli Andrea , Northern Samuel
Published: April 2023

The goal of this study is to revisit and contrast the original data from “School Library eBook Providers and Spanish Language Equity: An Analysis of eBook Collections Available to School Libraries.” Our original study examined the eBooks in Spanish provided by vendors of library resources to school libraries to determine if there are equitable offerings of eBooks in Spanish relative to the Spanish speaking school population in the United States. The processes in that study were replicated where possible and expanded upon for contextual understanding. Results indicate an increase in the Spanish language eBook options available in this replication study.
Mechanisms for committing virtual sexual offenses and their forensic psychiatric evaluation
Authors:   V. P. Serbsky National Medical Research Centre for Psychiatry and Narcology, Moscow, Russian Federation, Korchagin V. V. , Kamenskov M. Yu. ,   V. P. Serbsky National Medical Research Centre for Psychiatry and Narcology, Moscow, Russian Federation
Published: April 2023

The issues of an integrated approach to the forensic psychiatric assessment of persons who have committed sexual crimes by information and telecommunication technologies are considered. The main stages of decision-making are identified and analyzed. The features of the formation of ideas about the problem being solved, decision-making strategies, and the choice of alternatives are considered. Approaches to assessing the subject's ability to comprehend and regulate legally significant behavior are defined. An algorithm for forensic psychiatric assessment is formulated, according to which the most significant are the severity and nature of the leading psychopathological symptoms and the degree of its influence on the cognitive and volitional components of behavior regulation.
Sinergi Kebijakan Penyediaan Benih Unggul Kopi kelapa dan Mete untuk Pemulihan Ekonomi Nasional
Authors:   Kementerian Koordinator Bidang Perekonomian Republik Indonesia, Ahmad Afandi Frendy
Published: April 2023

Subsektor perkebunan menjadi tulang punggung perekonomian nasional (40 % dari PDB pertanian) karena menyerap tenaga kerja dan menyumbang devisa secara signifikan. Kebijakan penyediaan benih unggul berteknologi modern diperlukan untuk meremajakan tanaman perkebunan yang sudah tua agar meningkatkan daya saingnya. Validasi data dalam perumusan naksah kebijakan ini menggunakan metode in depth interview, FGD, observasi, dan rapat koordinasi yang disajikan secara kualitatif. Kebijakan pengembangan perbenihan tanaman perkebunan seperti kopi, kelapa, dan mete perlu dilakukan seperti kelapa sawit. Pilar sukses pengembangan pembibitan dilakukan dengan pemetaan kebutuhan pasar/industri, perancangan kebutuhan benih unggul, pemroduksian benih secara rutin, massal, serta mendekati lokasi penanaman. Selain itu diperlukan seleksi tanaman unggul untuk diperbanyak secara kultur jaringan dan menggunakan teknologi modern.
Kebijakan Pemasaran Kopi Robusta di Kabupaten Bogor
Authors:   Departemen Agribisnis, Fakultas Ekonomi dan Manajemen, IPB University, Miranda Vanesha , Yusalina Yusalina ,   Departemen Agribisnis, Fakultas Ekonomi dan Manajemen, IPB University
Published: April 2023

Potensi Kabupaten Bogor untuk pengembangan kopi Robusta pada faktanya melibatkan beberapa lembaga pemasaran yang melaksanakan fungsi-fungsi pemasaran. Pelaksanaan fungsi pemasaran menjadikan adanya penambahan nilai produk, sehingga terdapat perbedaan harga ditingkat produsen dan konsumen. Keterbatasan petani dalam mengakses dan menjangkau pasar konsumen akhir menjadi alasan dalam keterlibatan lembaga pemasaran. Policy brief ini sebagai langkah strategis dalam optimasi peran stakeholder dan policy maker dalam kegiatan pemasaran kopi Robusta di Kabupaten Bogor.
Model Komunikasi Kolaboratif untuk Keberlanjutan Bisnis pada Usaha Mikro Kecil di Geopark Nasional Pongkor
Authors:   Program Studi Komunikasi Pembangunan Pertanian dan Perdesaan, Fakultas Ekologi Manusia, IPB University, Sarbana Baban , Saleh Amiruddin ,   Departemen Sains Komunikasi dan Pengembangan Masyarakat, IPB University, Fatchiya Anna ,   Departemen Sains Komunikasi dan Pengembangan Masyarakat, IPB University, Firdaus Muhammad
Published: April 2023

Komunikasi kolaboratif merupakan pendekatan dalam mencapai keberlanjutan bisnis melalui peningkatan kompetensi kolaboratif pelaku Usaha Mikro Kecil (UMK). Pelaku UMK merupakan bagian dari komunitas lokal di wilayah Geopark yang memiliki prinsip melestarikan alam dan mensejahterakan warga. Pelaku UMK memiliki peran strategis dalam pengelolaan Geoproduct, yaitu komoditas yang memiliki keunikan dan keunggulan di wilayah Geopark. Geopark Nasional Pongkor terletak di Kabupaten Bogor dan ditetapkan dengan tujuan untuk konservasi edukasi dan pengembangan ekonomi. Keberlanjutan bisnis UMK dapat tercapai dengan adanya dukungan pemangku kepentingan peningkatan, kompetensi digital, geoliterasi, dan kompetensi kolaborasi.
CARDIOPATIA CONGÊNITA NO ADULTO: “TRANSPLANTE CARDÍACO: INDICAÇÕES, LIMITAÇÕES E DESAFIOS”
Authors:   Universidade de São Paulo. Faculdade de Medicina da FAMUSP, Azeka Estela , Dornelas Marques Raquel ,   InCor HCFMUSP, Arrieta Raul ,   InCor HCFMUSP, Siqueira Adailson ,   InCor HCFMUSP, Jatene Marcelo ,   InCor HCFMUSP
Published: April 2023

A insuficiência cardíaca é definida como síndrome clínica caracterizada por sintomas de intolerância aos exercícios na presença de anomalias estruturais e/ou funcionais do coração. Em adultos com cardiopatia congênita, ocorre como expressão das complicações e sequelas mesmo naqueles que foram submetidos a procedimentos cirúrgicos. O transplante cardíaco tem sido indicado em pacientes portadores de cardiopatias congênitas complexas refratárias a terapêutica convencional e após procedimentos cirúrgicos paliativos. Neste artigo, serão revistos a indicação de transplante, limitações e desafios nos adultos com cardiopatia congênita
COVID-19 CONTRIBUINDO COMO AGENTE DE MORBIDADE CARDIOVASCULAR
Authors:   Instituto de Cardiologia de Santa Catarina, Braga Santiago de Sá Valéria , Bonotto Mallmann Fabrício ,   Instituto de Cardiologia de Santa Catarina, Cegielka Rafael ,   Instituto de Cardiologia de Santa Catarina, Magalhães Pinto Gilvan ,   Instituto de Cardiologia de Santa Catarina, Caldara Barreto Ana Carolina ,   Instituto de Cardiologia de Santa Catarina
Published: April 2023

Caso de um paciente masculino de 40 anos, que apresentou síncope associada a miocardite durante quadro agudo de COVID-19. A miocardite é uma doença cardíaca inflamatória caracterizada por infiltrados inflamatórios sem causa isquêmica. O agente etiológico viral é o mais comumente identificável. O paciente tem histórico de tratamento imunossupressor devido a doença reumatológica. Diante deste quadro, podemos inferir que houve correlação do evento infeccioso com disautonomia sintomática. Podemos também considerar a hipótese de algum papel relevante do contexto imunológico predisponente à apresentação mais grave da doença viral aguda
PRINCIPAIS REPERCUSSÕES CLÍNICAS NAS CARDIOPATIAS CONGÊNITAS EM ADULTOS
Authors:   Escola de Enfermagem de Ribeirão Preto (EERP-USP), Nunes Emanuel , Gabiatti Daiane ,   Escola de Enfermagem de Ribeirão Preto (EERP-USP)
Published: April 2023

Introdução: As cardiopatias congênitas (CC) são malformações estruturais e funcionais do coração que ocorrem durante o período embrionário. No mundo, nascem anualmente 1,35 milhões de neonatos com CC. Devido a melhorias nas técnicas de cirurgia cardíaca neonatal e pediátrica para o tratamento das (CC), mais de 85% dos pacientes operados atingem a idade adulta. Objetivo: Conhecer as principais repercussões clínicas das cardiopatias congênitas em pacientes adultos. Método: Revisão integrativa da literatura realizada nas bases de dados EMBASE, LILACS, PubMed, Scopus, Web Of Science, e literatura cinzenta: Open Grey. Após aplicação da estratégia de busca nas bases de dados, os estudos identificados foram exportados para o gerenciador EndNote. Após identificação e remoção de estudos duplicados, foram exportadas para o aplicativo Rayyan web para seleção dos estudos. Todas as etapas foram realizadas de forma independente e mascarada pelos revisores. Os dados dos estudos incluídos foram analisados de forma descritiva. Resultados: Dos 1876 artigos identificados, cinco foram selecionados para compor a presente revisão. As repercussões clínicas mais prevalentes nas cardiopatias congênitas foram: hipertensão pulmonar, sopro cardíaco, dispneia progressiva, arritmias supraventriculares, hipertensão arterial, fibrilação atrial (FA), bloqueio atrio-ventricular (BAVT), insuficiência respiratória crônica. Conclusão: Apesar de algumas repercussões clínicas das CC em adultos também serem comuns nas cardiopatias adquiridas, a hipertensão pulmonar e sopro cardíaco podem ser um sinal de alerta para o profissional de saúde suspeitar de uma CC
Biomarkers and trace elements in beta thalassemia major
Authors: Khaleel Khaleed Jumaa
Published: April 2023

Introduction: Beta thalassemia is one of the most common inherited single gene disorders result from absent or reduced β - chain production. Regular blood transfusions are required to correct anemia for normal growth and development, this cause secondary iron overload which is responsible for peroxidative damage. Iron overload causes high concentrations of serum ferritin which is a protein that plays a key role in iron metabolism by binding and storing excess iron within cells. In β-thalassemia major, liver damage accounts for the changes in lipid profile including total-cholesterol (TC), high-density lipoprotein cholesterol (HDL-C) and triglyceride (TGL). Trace elements including zinc (Zn), copper (Cu) and magnesium (Mg) play a vital role in the body to perform its functions properly and should present in the body in appropriate amounts and must be available for reacting with other elements to form critical molecules as well as to participate in various important chemical reactions. The aims: to evaluate serum ferritin and trace elements (Copper, zinc and magnesium) and lipid profile in beta thalassemia major patients. Patients, material and methods: Patients: sixty patients were diagnosed as beta thalassemia major, they were on blood transfusion program, and thirty healthy medication free volunteers matched for age and sex were studied as control .Blood samples were taken after an overnight fast (12-14-hours.) and serum was obtained for estimation of ferritin levels by ELISA and for TC and TG that were determined enzymatically. The HDL-C was measured after precipitation of other lipoproteins .Copper; zinc and magnesium were estimated by Atomic Absorption Spectrophotometer. Results: A high ferritin level (747.55 ± 158.62 mg/l) was observed. The serum cholesterol and high density lipoprotein levels were found to be lower than normal control (94.4±7.48 and 40.83±4.64 mg/dl respectively), while serum triglyceride level was significantly higher than normal control (177.83±15.91). There was no correlation between serum ferittin and any of the studied lipids. Serum Copper and magnesium levels were significantly higher than normal control (152±6.4 mg/dl and 2.28±0.17 mg/dl respectively), while Serum zincs levels were significantly lower than normal (67.55±2.7 mg/dl) In conclusion : assessment of serum ferittin , trace elements and lipid profile in patients with beta thalassemia major revealed different levels in different studies suggesting variation in the factors influencing their levels in each patients and could be useful in follow up patients with beta thalassemia major.
Photoimmunotherapy by Cortactin monoclonal antibody conjugated with Hematoporphyrin derivative of a subcutaneous murine mammary adenocarcinoma using low power He-Ne laser
Authors: Al-Shammari Ahmed M.
Published: April 2023

Photoimmunotherapy (PIT) is a promising approach which aims to increase the specificity of photosensitisers used in photodynamic therapy through its conjugation to monoclonal antibodies (MAb) directed against tumour antigens. The current study aims to increase and improve the therapeutic selectivity of photodynamic therapy (PDT) by conjugating the HpD to specific (mAb) in order to target one of the specific antigens of mammary adenocarcinoma. a screening has been done to detect specific antigens on mammary adenocarcinoma cells and we found that Cortactin is the unique antigen on tumor tissue in our model, then anti-cortactin mAb was linked to HPD, used for not only improve specificity, but vastly enhances tumor cell killing when they are photo-immunotargeted by HpD-monoclonal antibody conjugates comparing with unconjugated HPD and then exposed to low power He-Ne laser (632 nm). Female mice, which were transplanted with AM3 (mouse mammary adenocarcinoma transplantable tumor line), were randomly divided into five groups of 10 mice each; the first group was treated by PIT using HpD conjugated with Cortactin, in comparison with HpD alone in a second group. The third and fourth were control groups with and without HpD alone respectively. Tumor growth indices and metastasis incidence were calculated. Photoimmunotargeting by HpD-mAb conjugates activated by a low-power He-Ne laser showed significant tumor growth inhibition similar to PDT using unconjugated HpD activated by He-Ne laser, whilst control groups were without any significant effect. The resultssuggest that conjugation was with low quantity of the HPD or not stable enough and this need further studies.