bluuebunny/crossref_metadata_2025 huggingface dataset:
Pengaruh Pendapatan Nasabah Terhadap Tingkat Pengembalian Pembiayaan Murabahah PT. Bank Muamalat Indonesia Tbk Kantor Cabang Binjai
Authors: Muhammad Fitra Dana  , Anjur Perkasa Alam
Published: March 2023

The purpose of this study was to determine the effect of the magnitude of the influence and the relationship between customer income on the rate of return on murabahah financing at PT. Bank Muamalat Indonesia, Tbk Binjai Branch Office. The type of research carried out is quantitative research that emphasizes numerical data (numbers) which is processed by inferential statistical methods (performing analysis of relationships between variables by testing hypotheses). The source of this research data was obtained from the answers to the questionnaire given by the research respondents, namely customers who received cheap financing from PT. Bank Muamalat Indonesia. The results of the study explain that there is a significant influence between customer income on the rate of return on murabahah financing at PT. Bank Muamalat Indonesia, Tbk Binjai Branch Office. The income of customers for their business affects the rate of return on murabahah financing provided by PT. Bank Muamalat Indonesia, Tbk Binjai Branch Office to these customers amounted to 89.4%. There is a positive or in line between the Customer's Income (X) and the Rate of Return on Murabahah Financing (Y)
Understanding Similarity through Dilations of Nonstandard Shapes
Authors: Basu Marina , Koellner Karen , Jacobs Jennifer K. , Seago Nanette
Published: March 2023

This set of tasks progressively engages students in geometric proportional reasoning.
“Culturally Responsive Mathematics Teaching and English Language Learners”
Authors: Torres-Velasquez Diane , Lobo Gilberto , Parker Introduction by: Sarah , MeCaskey Rebecca , Robichaux-Davis Rebecca R.
Published: March 2023

From the Archives highlights articles from NCTM’s legacy journals, previously discussed by the MTLT Journal Club.
Teaching Is a Journey: Faculty Speech at Closing Assembly
Authors: King Alessandra
Published: March 2023

This department provides a space for current and past PK-12 teachers of mathematics to connect with other teachers of mathematics through their stories that lend personal and professional support.
A análise do comportamento dos tecidos sobre o corpo humano: uma abordagem para o ensino de desenho de moda
Authors: Zamprogna Lucíola Stenhaus Pires , Lugli Daniele M.
Published: March 2023

O desenho de moda é uma valiosa ferramenta na comunicação de ideias e conceitos relacionados ao desenvolvimento de produtos do vestuário. Nesse processo, é necessário considerar que cada tecido possui características próprias, e sua interação com o corpo humano gera um série de efeitos que precisam ser representados com precisão para que o resultado seja coerente com a realidade. O estudo do comportamento dos tecidos é denominado panejamento, e o presente artigo analisa como ele se manifesta nas belas artes e no desenho de moda com o objetivo de incorporar tal conceito a uma prática pedagógica baseada na construção do conhecimento, que estaria alinhada à formação de um profissional criativo capaz de propor soluções inovadoras.
Kinas historiske erfaring og den globale demokratikrise – Et interview med Wang Hui
Authors: Møller Mulvad Andreas
Published: March 2023

Kinas historiske erfaring og den globale demokratikrise – Et interview med Wang Hui
Bien-être en classe de musique d’élèves du primaire inscrits à un programme Arts-études
Authors: Tardif Catherine , Boucher Hélène , Lane Julie
Published: March 2023

L’objectif de cet article est de décrire le bien-être psychologique de 164 élèves de la 3e à la 6e année du primaire inscrits à un programme Arts-études en musique au Québec. Les résultats soulignent des différences significatives selon le genre et le niveau scolaire des participants. Entre autres, les filles rapportent plus de plaisir et de motivation que les garçons. Les élèves de 6e année indiquent éprouver moins de plaisir, de satisfaction, de motivation, avoir une moins haute estime de soi et une perception plus négative du climat d’appartenance que ceux de 3e et de 4e année. L’origine de la participation au programme (suggestion des parents ou demande de l’enfant) serait un modérateur de ces effets. Il semble ainsi qu’une attention particulière doit être portée quant au bien-être en classe des garçons de 6e année dont les parents suggèrent la participation à un tel programme.
LES BONNES HUMEURS, LE BONHEUR ET LE BIEN-ÊTRE
Authors: Lepine Samuel
Published: March 2023

Dans cet article, je propose d’analyser le concept de bonheur en termes d’humeurs positives. Je montre que cette analyse constitue une voie moyenne entre l’analyse du bonheur comme émotion et l’analyse du bonheur en termes de propensions émotionnelles. Je soutiens plus particulièrement qu’être heureux consiste à ressentir une humeur positive, quelle que soit cette humeur. Cette analyse est donc réductionniste – être heureux n’est rien d’autre qu’être de bonne humeur – et pluraliste –nos bonnes humeurs, dans toute leur diversité, constituent autant de manières différentes d’être heureux. Afin de soutenir cette approche, je défends la thèse selon laquelle les humeurs sont des attitudes prospectives, consistant à évaluer l’impact affectif possible de notre environnement sur nos états motivationnels tels que nos désirs ou nos préférences. Je m’efforce ensuite d’explorer les relations que le bonheur entretient avec le bien-être à partir de cette analyse du bonheur comme bonne humeur.
Trauma transgeneracional y posmemoria entre nietos de víctimas de la dictadura chilena
Authors: Cabrera Sánchez José
Published: March 2023

This article is the result of a research project whose objective was to analyze memory building among the grandchildren of victims of human rights violations during the Chilean dictatorship, and which attempted to identify and interpret post-memorial work strategies related to the elaboration of the traumatic memory transmitted by previous generations. The conceptual framework is based on two theoretical proposals: psychoanalytic approaches to trauma and the concept of post-memory developed by Marianne Hirsch. Both theoretical references are congruent with the qualitative nature of the research, as they sustain an interpretative approach to processes of meaning that unfold discursively. They inform on phenomena of subjectivation that reveal the interweaving of the individual and the social in the constitution of memory, and the processes of transmission between generations that participate in memory building and the elaboration of trauma. The methodology is qualitative and is based on the analysis of semi-structured focused interviews with fifteen grandchildren of political prisoners or disappeared detainees of the Chilean civil-military dictatorship. We conclude that the grandchildren organize imaginary and symbolic narratives of memory by means of which they figure the traumatic experience of their grandparents. This figuration is not intended to fill the gap in the transmission of traumatic memory, but rather acknowledges the loss and enables an elaboration of the trauma that follows the logic of mourning according to the psychoanalytic perspective, making use of representational mechanisms that take the form of what Hirsch calls post-memorial work.
Art + DIY Electronics
Authors: Hertz Garnet
Published: March 2023

A systematic theory of DIY electronic culture, drawn from a century of artists who have independently built creative technologies.

Since the rise of Arduino and 3D printing in the mid-2000s, do-it-yourself approaches to the creative exploration of technology have surged in popularity. But the maker movement is not new: it is a historically significant practice in contemporary art and design. This book documents, tracks, and identifies a hundred years of innovative DIY technology practices, illustrating how the maker movement is a continuation of a long-standing creative electronic subculture. Through this comprehensive exploration, Garnet Hertz develops a theory and language of creative DIY electronics, drawing from diverse examples of contemporary art, including work from renowned electronic artists such as Nam June Paik and such art collectives as Survival Research Laboratories and the Barbie Liberation Organization.

Hertz uncovers the defining elements of electronic DIY culture, which often works with limited resources to bring new life to obsolete objects while engaging in a critical dialogue with consumer capitalism. Whether hacking blackboxed technologies or deploying culture jamming techniques to critique commercial labor practices or gender norms, the artists have found creative ways to make personal and political statements through creative technologies. The wide range of innovative works and practices profiled in Art + DIY Electronics form a general framework for DIY culture and help inspire readers to get creative with their own adaptations, fabrications, and reimaginations of everyday technologies.
Targeting the fatty acid binding proteins disrupts multiple myeloma cell cycle progression and MYC signaling
Authors: Farrell Mariah , Fairfield Heather , Karam Michelle , D'Amico Anastasia , Murphy Connor S , Falank Carolyne , Pistofidi Romanos Sklavenitis , Cao Amanda , Marinac Catherine R , Dragon Julie A , McGuinness Lauren , Gartner Carlos G , Iorio Reagan Di , Jachimowicz Edward , DeMambro Victoria , Vary Calvin , Reagan Michaela R
Published: March 2023

Multiple myeloma is an incurable plasma cell malignancy with only a 53% 5-year survival rate. There is a critical need to find new multiple myeloma vulnerabilities and therapeutic avenues. Herein, we identified and explored a novel multiple myeloma target: the fatty acid binding protein (FABP) family. In our work, myeloma cells were treated with FABP inhibitors (BMS3094013 and SBFI-26) and examined in vivo and in vitro for cell cycle state, proliferation, apoptosis, mitochondrial membrane potential, cellular metabolism (oxygen consumption rates and fatty acid oxidation), and DNA methylation properties. Myeloma cell responses to BMS309403, SBFI-26, or both, were also assessed with RNA sequencing (RNA-Seq) and proteomic analysis, and confirmed with western blotting and qRT-PCR. Myeloma cell dependency on FABPs was assessed using the Cancer Dependency Map (DepMap). Finally, MM patient datasets (CoMMpass and GEO) were mined for FABP expression correlations with clinical outcomes. We found that myeloma cells treated with FABPi or with FABP5 knockout (generated via CRISPR/Cas9 editing) exhibited diminished proliferation, increased apoptosis, and metabolic changes in vitro. FABPi had mixed results in vivo, in two pre-clinical MM mouse models, suggesting optimization of in vivo delivery, dosing, or type of FABP inhibitors will be needed before clinical applicability. FABPi negatively impacted mitochondrial respiration and reduced expression of MYC and other key signaling pathways in MM cells in vitro. Clinical data demonstrated worse overall and progression-free survival in patients with high FABP5 expression in tumor cells. Overall, this study establishes the FABP family as a potentially new target in multiple myeloma. In MM cells, FABPs have a multitude of actions and cellular roles that result in the support of myeloma progression. Further research into the FABP family in MM is warrented, especially into the effective translation of targeting these in vivo.
Symbolic expression generation via variational auto-encoder
Authors: Popov Sergei , Lazarev Mikhail , Belavin Vladislav , Derkach Denis , Ustyuzhanin Andrey
Published: March 2023

There are many problems in physics, biology, and other natural sciences in which symbolic regression can provide valuable insights and discover new laws of nature. Widespread deep neural networks do not provide interpretable solutions. Meanwhile, symbolic expressions give us a clear relation between observations and the target variable. However, at the moment, there is no dominant solution for the symbolic regression task, and we aim to reduce this gap with our algorithm. In this work, we propose a novel deep learning framework for symbolic expression generation via variational autoencoder (VAE). We suggest using a VAE to generate mathematical expressions, and our training strategy forces generated formulas to fit a given dataset. Our framework allows encoding apriori knowledge of the formulas into fast-check predicates that speed up the optimization process. We compare our method to modern symbolic regression benchmarks and show that our method outperforms the competitors under noisy conditions. The recovery rate of SEGVAE is 65% on the Ngyuen dataset with a noise level of 10%, which is better than the previously reported SOTA by 20%. We demonstrate that this value depends on the dataset and can be even higher.
Determinants of age-related decline in walking speed in older women
Authors: Martins Valéria Feijó , Tesio Luigi , Simone Anna , Gonçalves Andréa Kruger , Peyré-Tartaruga Leonardo A.
Published: March 2023

Background

Walking speed is reduced with aging. However, it is not certain whether the reduced walking speed is associated with physical and coordination fitness. This study explores the physical and coordination determinants of the walking speed decline in older women.

Methods

One-hundred-eighty-seven active older women (72.2 ± 6.8 years) were asked to perform a 10-m walk test (self-selected and maximal walking speed) and a battery of the Senior fitness test: lower body strength, lower body flexibility, agility/dynamic balance, and aerobic endurance. Two parameters characterized the walking performance: closeness to the modeled speed minimizing the energetic cost per unit distance (locomotor rehabilitation index, LRI), and the ratio of step length to step cadence (walk ratio, WR). For dependent variables (self-selected and maximal walking speeds), a recursive partitioning algorithm (classification and regression tree) was adopted, highlighting interactions across all the independent variables.

Results

Participants were aged from 60 to 88 years, and their self-selected and maximal speeds declined by 22% and 26% (p < 0.05), respectively. Similarly, all physical fitness variables worsened with aging (muscle strength: 33%; flexibility: 0 to −8 cm; balance: 22%; aerobic endurance: 12%; all p < 0.050). The predictors of maximal walking speed were only WR and balance. No meaningful predictions could be made using LRI and WR as dependent variables.

Discussion

The results suggest that at self-selected speed, the decrease in speed itself is sufficient to compensate for the age-related decline in the motor functions tested; by contrast, lowering the WR is required at maximal speed, presumably to prevent imbalance. Therefore, any excessive lowering of LRI and WR indicates loss of homeostasis of walking mechanics and invites diagnostic investigation.
Functional verification of the JmLFY gene associated with the flowering of Juglans mandshurica Maxim.
Authors: Cai Jiayou , Jia Ruoxue , Jiang Ying , Fu Jingqi , Dong Tianyi , Deng Jifeng , Zhang Lijie
Published: March 2023

In this study, a pBI121-JmLFY plant expression vector was constructed on the basis of obtaining the full-length sequence of the JmLFY gene from Juglans mandshurica, which was then used for genetic transformation via Agrobacterium inflorescence infection using wild-type Arabidopsis thaliana and lfy mutants as transgenic receptors. Seeds of positive A. thaliana plants with high expression of JmLFY were collected and sowed till the homozygous T3 regeneration plants were obtained. Then the expression of flowering-related genes (AtAP1, AtSOC1, AtFT and AtPI) in T3 generation plants were analyzed and the results showed that JmLFY gene overexpression promoted the expression of flowering-related genes and resulted in earlier flowering in A. thaliana. The A. thaliana plants of JmLFY-transformed and JmLFY-transformed lfy mutants appeared shorter leaves, longer fruit pods, and fewer cauline leaves than those of wild-type and the lfy mutants plants, respectively. In addition, some secondary branches in the transgenic plants converted into inflorescences, which indicated that the overexpression of JmLFY promoted the transition from vegetative growth to reproductive growth, and compensate the phenotypic defects of lfy mutant partially. The results provides a scientific reference for formulating reasonable genetic improvement strategies such as shortening childhood, improving yield and quality, and breeding desirable varieties, which have important guiding significance in production.
Eliciação de crenças sobre a doação de leite humano: uma aplicação da teoria do comportamento planejado
Authors: Pinheiro Romel , Reinert Franciane , De Souza Maria José Barbosa
Published: March 2023

O objetivo desse trabalho foi identificar as crenças salientes mencionadas por potenciais doadoras quando pensam em realizar a doação de leite humano (DLH), baseado na teoria do comportamento planejado (TCP). Para isso, foram realizadas 30 entrevistas online, de forma síncrona, com uso de telefone e aplicativo de WhatsApp. A amostra foi por conveniência e as participantes foram puérperas aptas a doar. Os itens da entrevista foram baseados na TCP e a análise de conteúdo foi usada para analisar as transcrições das entrevistas. Os principais resultados sugerem que as participantes sabem que a DLH ajudará os bebês, que esses bebês não dispõem do leite da mãe, e que essa doação ajudará às mães que não dispõem de leite para amamentar; a família é o principal grupo de referência para essa doação; que produzir muito leite e dispor da coleta em domicílio facilitariam essa doação, e que ter pouco tempo para expressar o leite e dispor de frasco para armazená-lo dificultariam essa doação. As conclusões indicam que essas crenças podem subsidiar a elaboração de programas de marketing social, desde que não sejam usadas em estudos que tratem de comportamentos e população diferentes.
Desafios regulatórios à promoção da fonte solar fotovoltaica no Brasil
Authors: Fernandes José Eduardo Stort , Belchior Fernando Nunes , Domingos José Luis
Published: March 2023

O presente trabalho tem como propósito investigar desafios relacionados ao processo de transição energética no Brasil, especialmente para a energia solar fotovoltaica (FV). A metodologia pretende analisar, a partir de modelos de tratamento de dados multicritério, o contexto regulatório, técnico e socioeconômico brasileiro, assim como caracterizar as vantagens e as desvantagens de longo prazo a consumidoras e concessionárias. Este resumo apresenta uma breve descrição da proposta de pesquisa e suas etapas, onde o objetivo principal é mostrar que o processo de transição energética para a fonte FV depende fortemente de incentivos governamentais, além da atuação integrada de vários atores envolvidos na cadeia transição.
Use of Leukotriene-Receptor Antagonists During Pregnancy and Risk of Neuropsychiatric Events in Offspring
Authors: Tsai Hui-Ju , Wu Chi-Shin , Chang Yen-Chen , Yao Tsung-Chieh
Published: March 2023

This cohort study examines the association of the use of leukotriene-receptor antagonists during pregnancy with the risk of neuropsychiatric events in offspring.
Light Fueled Manipulation of Bubble Motion Against Buoyancy via Photosensitive Substrate
Authors: Li Haonan , Yang Yijing , Zhu Xun , Wang Hong , Ye Dingding , Yang Yang , Liao Qiang , Chen Rong
Published: March 2023

Flexibly and precisely controlling bubbles is of paramount significance for biological and chemical analysis, reaction engineering, etc. However, the buoyancy force acting on bubbles is significant, making it difficult to precisely manipulate bubbles. Particularly, controlling the anti‐buoyancy motion of bubbles remains a fundamental challenge. Herein, a versatile light strategy for manipulating the anti‐buoyancy motion of bubbles via a photosensitive substrate is developed. Upon focused laser beam irradiation, an intense Marangoni effect associated with non‐uniform temperature distribution is induced underneath the bubble. The created excess Laplace pressure drives the bubble to move against the buoyancy force downward to the focused‐laser‐acted region, manifesting an excellent phototaxis motion. Theoretical analysis demonstrates that the Marangoni effect is responsible for actuating the anti‐buoyancy motion of a bubble. With this light strategy, the bubble collection, transportation, and on‐demand release can be flexibly implemented. Moreover, the phototaxis motion of bubbles inspires a manipulation protocol via the integration of 3D‐structured design of photosensitive substrate. This light strategy for manipulating bubbles not only possesses sufficiently high accuracy and quick response, but also circumvents the limitation of the liquid volatility and multi‐dimensional motion, which provides new ideas for rational control of bubble behaviors.
Recovery of eutrophized marine ecosystems using the European flat oyster, Ostrea edulis
Authors: Albentosa M. , Akinyemi M. I. , Vera M. , Ibarrola I. , Filgueira R. , Galimany E. , da Costa F. , Pardo B. G. , Vázquez‐Luis M. , Hernández A. , Hernandis S. , Martínez P.
Published: March 2023

The development of tourism and intensification of agriculture has released large amounts of nitrogen and phosphorus into the Mar Menor coastal lagoon in South‐east Spain, resulting in a phytoplankton bloom in 2016. This bloom turned the clear and transparent waters turbid and greenish, and killed approximately 85% of benthic macrophytes.

Nutrient bioextraction by flat oysters, Ostrea edulis, has been proposed for remediation of these eutrophication events and water quality recovery.

This research aims to quantify the clearance rate and investigate the genetic origin of Mar Menor oysters under eutrophized conditions for potential applications to bioremediation projects. Oligotrophic and eutrophic conditions were replicated in the laboratory, and oyster feeding behaviour (i.e. clearance rates, ingestion rates, absorption efficiency and absorption rates) were studied using a flow‐through system.

The genetic characterization of oysters showed no significant difference between individuals from the Mar Menor and individuals collected from a nearby Mediterranean bed (Tabarca Island).

Based on the physiological results observed, oysters were grouped into high‐feeder (HF) and low‐feeder (LF) categories according to their clearance rate, that was 3‐fold higher in the HF group. Different responses in feeding behaviour were observed under eutrophic conditions in both oyster groups. Constraints in the absorption capacity of LF oysters seemed to be related to their reduced filtering activity. Lower body condition of LF oysters was evidenced by their negative scope for growth value.

From this work, several conclusions can be drawn for future restoration/bioextraction actions: (i) the recovery of half of the oyster population that existed in the past would act as an effective top‐down control on the phytoplankton community; (ii) using clearance rate measurements is recommended to select oysters as broodstock; and (iii) Mediterranean oysters could be used as broodstock in the event that Mar Menor oysters fail to reproduce.
Roles of eddy generation and jet characteristics in setting the annual cycle of Siberian storm track
Authors: Xiong Meng , Ren Hong‐Li , Nie Yu , Feng Guolin , Wang Lei
Published: March 2023

The Siberian storm track is one of the drivers of the East Asian extreme weather events. Using the daily JRA‐55 reanalysis data from 1980 to 2021, this study examines roles of eddy generation and jet characteristics in setting the annual cycle of Siberian storm track. It is found that there are two peaks of Siberian storm track intensity in boreal spring and autumn. The possible reason for such an annual cycle is explored by analyzing the maximum Eady growth rate over the Siberian region and jet characteristics. The stronger Siberian Eady growth rate in boreal spring and autumn, favoring a stronger baroclinic eddy generation, could contribute to the stronger intensity of Siberian storm tracks in these two seasons. Furthermore, the Siberian jet stream cores during boreal spring and autumn are located north of 50° N and resembles more an eddy‐driven jet. While in winter, the subtropical jet stream enhanced and the eddy‐driven jet becomes relatively weaker, which is less efficient to generate midlatitude baroclinic eddies. Besides, the eddy‐driven jet can modulate the horizontal wave propagations from upstream, which also plays a role in amplifying the spring and autumn Siberian storm tracks.
The passive avoidance task ameliorate the toxic effects of bisphenol A on dopamine D1 receptor density in hippocampus, amygdala, and cerebellum of male rats
Authors: Taherianfard* Mahnaz , Ahmadijokani Saiedeh
Published: March 2023

Introduction

Dopamine D1 receptor seems to play a role in mediating plasticity. Therefore, the present study aimed to investigate the effects of passive avoidance tasks postexposed to BPA on dopamine D1 receptor density in the hippocampus, amygdala, and cerebellum of male rats.

Methods

Thirty‐five male Sprague–Dawley rats weighing 220.300 g, in standard light‐dark 12 h light/12 h dark were used in the present study; water and food were ad libitum. Animals were divided into six groups. Administration of BPA 5 and 50 mg/kg/day were gavaged for 15 days. Learning and memory assessment were done by a shuttle box after 15 days of BPA administration. The density of the dopamine D1 receptor was investigated using an immunohistochemistry (IH) procedure. For determining the color difference in IH sections, Image Analyzer software was used. The data were analyzed by one‐way ANOVA followed by Tukey's as a post hoc test.

Results

The data showed that BPA in both doses could significantly increase the density of dopamine D1 receptors in the hippocampus, amygdala, and cerebellum of male rats; learning in rats postexposed to BPA improves dopamine D1 receptor density significantly in three brain structures.

Discussion

According to the results, passive avoidance learning and memory can improve the density of dopamine D1 receptors in the hippocampus, amygdala, and cerebellum of male rats.
Early development of respiratory motor circuits in larval zebrafish (Danio rerio)
Authors: McArthur Kimberly L. , Tovar Victoria M. , Griffin‐Baldwin Emmett , Tovar Bria D. , Astad Emma K.
Published: March 2023

Rhythm‐generating circuits in the vertebrate hindbrain form synaptic connections with cranial and spinal motor neurons, to generate coordinated, patterned respiratory behaviors. Zebrafish provide a uniquely tractable model system to investigate the earliest stages in respiratory motor circuit development in vivo. In larval zebrafish, respiratory behaviors are carried out by muscles innervated by cranial motor neurons—including the facial branchiomotor neurons (FBMNs), which innervate muscles that move the jaw, buccal cavity, and operculum. However, it is unclear when FBMNs first receive functional synaptic input from respiratory pattern‐generating neurons, and how the functional output of the respiratory motor circuit changes across larval development. In the current study, we used behavior and calcium imaging to determine how early FBMNs receive functional synaptic inputs from respiratory pattern‐generating networks in larval zebrafish. Zebrafish exhibited patterned operculum movements by 3 days postfertilization (dpf), though this behavior became more consistent at 4 and 5 dpf. Also by 3dpf, FBMNs fell into two distinct categories (“rhythmic” and “nonrhythmic”), based on patterns of neural activity. These two neuron categories were arranged differently along the dorsoventral axis, demonstrating that FBMNs have already established dorsoventral topography by 3 dpf. Finally, operculum movements were coordinated with pectoral fin movements at 3 dpf, indicating that the operculum behavioral pattern was driven by synaptic input. Taken together, this evidence suggests that FBMNs begin to receive initial synaptic input from a functional respiratory central pattern generator at or prior to 3 dpf. Future studies will use this model to study mechanisms of normal and abnormal respiratory circuit development.
NNPEC: Neighborhood node propagation entropy centrality is a unique way to find the influential node in a complex network
Authors: Chakravarthy Thota Seshu , Selvaraj Lokesh
Published: March 2023

In complicated networks, it is still difficult to determine which nodes are influential. To increase the accuracy for identifying influential nodes (IN), several measures have been undertaken in complex networks (CN). Reviewing the research on network attacks, information distribution, and pandemic spread require identifying effective INs. As a result, determining INs in complicated networks has attracted more and more attention toward researchers. Various approaches have been proposed in recent years, each with pros and cons. The development of algorithms to study static social networks has been the focus of previous research. However, social networks are dynamic networks that change over time and are not static. The impact of source localization is generally weak since most existing approaches do not fully exploit the infection of neighboring information in nodes. This research proposes a novel Neighborhood Node Propagation Entropy Centrality (NNPEC) technique for finding the INs in CNs. This technique also helps to identify the neighborhood node entropy and determines each node's ability to spread among uninfected neighboring nodes. The proposed strategy is applied to six different datasets from different domains, including C‐Elegance, Dolphins, Facebook, Gowalla, Karate, and USA Power Grid. Some of the performance evaluations, like maximum degree (MD), average degree (AD), number of nodes, edges and cluster coefficient (CC), are analyzed and compared with different existing algorithms. In the experimental section, a proposed method obtained an MD of 16.66, CC of 0.564, AD of 3.92, edges of 76 and nodes of 33 for the karate dataset. Also, some other existing techniques are compared to prove the efficiency of the proposed method.
How to Open the Ring of a Di‐ene‐Substituted‐δ‐Valerolactone: From Carbon Dioxide and 1,3‐Butadiene to Functional Polyesters
Authors: Chen Kaihao , Mei Yixuan , Zhang Zhuorui , Ling Jun , Ni Xufeng
Published: March 2023

As a substituted‐δ‐valerolactone, α‐ethylidene‐δ‐vinyl‐δ‐valerolactone (EVL) provides a method of utilizing carbon dioxide with 1,3‐butadiene to produce functional polymers. Its di‐ene‐substituted lactone ring was considered inactive in polymerization in the past two decades, while successful polymerization attempts of EVL have been reported very recently. Novel synthetic strategies and functional polymers from EVL have been developed. The ring‐opening reactions of EVL and the corresponding polymers as well as the ring‐opening (co)polymerizations of EVL and its derivatives are highlighted in this review. The obtained functional polymers with or without facile post‐polymerization modification possess unique properties, such as amphipathy, elasticity, peel resistance, etc., allowing for application potential in various fields.
UAV‐Based Prediction of Sugarbeet Yield and Quality
Authors: Walsh Olga S.
Published: March 2023

In Idaho, nitrogen (N) and water management are two major factors affecting sugarbeet yield and quality. If sugarbeet crop yield potential can be accurately predicted early in the growing season, then the crop can be topdressed based on crop nutrient requirements. This approach has the potential to improve the economic returns to sugarbeet growers and processors. The objective of this study was to assess the feasibility of predicting root yield and estimated recoverable sugar using UAV‐based normalized difference vegetation index (NDVI) in sugarbeets grown under varied N and water rates. Earn 0.5 CEUs in Crop Management by reading the article and taking the quiz at https://web.sciencesocieties.org/Learning‐Center/Courses.
The approach of hybrid adaptive coupling synchronization among N Lorenz systems and its application in secure communication for multi‐unmanned aerial vehicle formation
Authors: Xu Wei , Cao Ning
Published: March 2023

In this paper, it is proposed that a hybrid global adaptive coupling synchronization scheme among
Lorenz chaotic dynamical nodes to realize the secure communication system between base station and multi‐unmanned aerial vehicle (UAV) formation. The specific method is that the feedback drive–response synchronization is utilized for first two nodes of base station and the leader of multi‐UAV formation, and the nodes of all UAVs are coupled by unidirectional adaptive coupling synchronization according to a directed link in ad hoc network of multi‐UAV formation. It is demonstrated that the asymptotic stability of the proposed hybrid adaptive coupled synchronization by constructing the Lyapunov function. In this way, the encrypted information formed by plaintext information masked into the chaotic sequence generated by the chaotic dynamical node of base station; meanwhile, it is fed back into the base station node as the drive system. On the other hand, encrypted information is forwarded to the leader node as the response system for decryption. The feedback driver–response synchronization is used to realize secure communication between the base station and the leader of multi‐UAV formation. Meanwhile, secure communication among its leader and followers is achieved through the unidirectional adaptive coupling synchronization in the network. This strategy ensures the multi‐UAV formation decrypting encrypted information synchronously and effectively improves the security, consistency, and overall performance of their commands.
The relationship of psychological well‐being and cognitive emotions with breastfeeding self‐efficacy in mothers in the postpartum period
Authors: Çankaya Seyhan , Ataş Ayşenur
Published: March 2023

To determine the relationship of psychological well‐being and cognitive emotion regulation and breastfeeding self‐efficacy in mothers in the postpartum period. The research was designed as cross‐sectional and correlational and carried out between 1 November 2021 and 1 January 2022 in the pediatric outpatient clinic of a Medical Faculty Hospital of a province in the Central Anatolian Region of Turkey. Responses from a total of 325 mothers who were in postpartum 1–6 months were analyzed. Data were collected using a Personal Information Form, the Scales of Psychological Well‐Being (SPWB), the Cognitive Emotion Regulation Questionnaire (CERQ), and the Breastfeeding Self‐Efficacy Scale‐Short Form (BSES‐SF). The following factors were found to be important associated risk factors that negatively affected breastfeeding self‐efficacy in 29% of the mothers (F = 14.536, p < .001): mothers' poor mental health, using self‐blaming maladaptive cognitive coping strategy, inability to use positive reappraisal coping strategy, and feeding the baby only formula or both breast milk and formula. Weak and positive correlations were found between psychological well‐being of mothers and adaptive cognitive coping subdimensions, and negative and weak correlations were found between psychological well‐being of the mothers and maladaptive cognitive coping subdimensions (p < .001). Breastfeeding self‐efficacy of mothers in a well psychological state, who can use adaptive cognitive coping strategies, and who exclusively breastfeed their babies is positively affected.
Evaluation of the herbicide glyphosate, (aminomethyl)phosphonic acid, and glyphosate‐based formulations for genotoxic activity using in vitro assays
Authors: Smith‐Roe Stephanie L. , Swartz Carol D. , Rashid Asma , Christy Nicholas C. , Sly Jamie E. , Chang Xiaoqing , Sipes Nisha S. , Shockley Keith R. , Harris Shawn F. , McBride Sandra J. , Larson Gary J. , Collins Bradley J. , Mutlu Esra , Witt Kristine L.
Published: March 2023

Glyphosate, the most heavily used herbicide world‐wide, is applied to plants in complex formulations that promote absorption. The National Toxicology Program reported in 1992 that glyphosate, administered to rats and mice at doses up to 50,000 ppm in feed for 13 weeks, showed little evidence of toxicity, and no induction of micronuclei was observed in the mice in this study. Subsequently, mechanistic studies of glyphosate and glyphosate‐based formulations (GBFs) that have focused on DNA damage and oxidative stress suggest that glyphosate may have genotoxic potential. However, few of these studies directly compared glyphosate to GBFs, or effects among GBFs. To address these data gaps, we tested glyphosate, glyphosate isopropylamine (IPA), and (aminomethyl)phosphonic acid (AMPA, a microbial metabolite of glyphosate), 9 high‐use agricultural GBFs, 4 residential‐use GBFs, and additional herbicides (metolachlor, mesotrione, and diquat dibromide) present in some of the GBFs in bacterial mutagenicity tests, and in human TK6 cells using a micronucleus assay and a multiplexed DNA damage assay. Our results showed no genotoxicity or notable cytotoxicity for glyphosate or AMPA at concentrations up to 10 mM, while all GBFs and herbicides other than glyphosate were cytotoxic, and some showed genotoxic activity. An in vitro to in vivo extrapolation of results for glyphosate suggests that it is of low toxicological concern for humans. In conclusion, these results demonstrate a lack of genotoxicity for glyphosate, consistent with observations in the NTP in vivo study, and suggest that toxicity associated with GBFs may be related to other components of these formulations.
A recent paradigm on iron absorption, prevalence, and emerging dietary approaches to eradicate iron deficiency
Authors: Malhotra Umang , Roy Mrinmoy , Sontakke Manmath , Choudhary Pintu
Published: March 2023

Iron is an essential micronutrient required for growth and development during all stages of human life with the most important function of oxygen transportation via hemoglobin. With the prevalence of the triple burden of malnutrition in the world, there is an increase in iron deficiency anemia affecting a lot of people, especially the adolescent population of girls. The diagnosis of iron deficiency anemia is confirmed by low iron stores and decreased hemoglobin levels. It is prevalent in both urban and rural regions; however, gender differences exist which start from the age of 15 years, as females are more prone to develop iron deficiency. On comparing the 4th and 5th surveys conducted by the National Family Health Survey, India, it can be observed that the prevalence of anemia has increased which is a major cause of concern. One of the major reasons that people suffer from this deficiency would be vegetarianism. Plant sources contain iron but they are present in the ferric state which needs to be converted to the ferrous state. The bioavailability of plant sources is low therefore, this condition can be tackled by adopting steps like dietary diversification, biofortification, fortification, and supplementation.
Nonlinear vibration phenomena in hydrodynamically supported rotor systems
Authors: Nitzschke Steffen , Woschke Elmar , Strackeljan Cornelius
Published: March 2023

It is a well‐known fact, that hydrodynamically supported systems are prone to nonlinear vibrations. Their exact simulative prediction with respect to frequency and amplitude is complicated by the fact that different system properties interact. The paper at hand outlines an approach that takes all relevant influences like rigid body motions, elastic deformations, nonlinear relation between fluid film pressure and bearing kinematics as well as temperature increase due to power loss or adjacent heat sources into account as detailed as necessary. Both journal and thrust bearings are considered as they contribute to the system's stiffness and damping capabilities. The approach is applied to self‐excited pad vibrations of tilting pad thrust bearings as well as the run‐up simulation of a turbocharger rotor under different axial loads. Both models are validated against measurements.
Using graph theory as a common language to combine neural structure and function in models of healthy cognitive performance
Authors: Litwińczuk Marta Czime , Muhlert Nils , Trujillo‐Barreto Nelson , Woollams Anna
Published: March 2023

Graph theory has been used in cognitive neuroscience to understand how organisational properties of structural and functional brain networks relate to cognitive function. Graph theory may bridge the gap in integration of structural and functional connectivity by introducing common measures of network characteristics. However, the explanatory and predictive value of combined structural and functional graph theory have not been investigated in modelling of cognitive performance of healthy adults. In this work, a Principal Component Regression approach with embedded Step‐Wise Regression was used to fit multiple regression models of Executive Function, Self‐regulation, Language, Encoding and Sequence Processing with a collection of 20 different graph theoretic measures of structural and functional network organisation used as regressors. The predictive ability of graph theory‐based models was compared to that of connectivity‐based models. The present work shows that using combinations of graph theory metrics to predict cognition in healthy populations does not produce a consistent benefit relative to making predictions based on structural and functional connectivity values directly.
Utility of gamma‐glutamyl transpeptidase to lymphocyte count ratio in predicting prognosis of patients with oral cancer: A prospective cohort study in Southeastern China
Authors: Wang Na , Lin Yulan , Chen Fa , Liu Fengqiong , Wang Jing , Gao Bingju , Qiu Yu , Lin Lisong , Shi Bin , He Baochang
Published: March 2023

Background

To assess the prognostic role of gamma‐glutamyl transpeptidase to lymphocyte count ratio (GLR) and develop a prognostic nomogram for patients with oral cancer.

Methods

A prospective cohort (n = 1011) was conducted during July 2002 to March 2021 in Southeastern China.

Results

The median follow‐up time was 3.5 years. Multivariate Cox regression (OS: HR = 1.51, 95% CI: 1.04, 2.18) and Fine–Gray model (DSS: HR = 1.68, 95% CI: 1.14, 2.49) both showed that high GLR could act as an indicator of poor prognosis. A nonlinear dose–response relationship was observed between continuous GLR and the risk of all‐cause mortality (p for overall = 0.028, p for nonlinear = 0.048). Compare with TNM stage, time‐dependent ROC curve proved that GLR‐based nomogram model performs better in predicting prognosis (the area under curve for 1‐, 3‐, and 5‐years mortality: 0.63, 0.65, and 0.64 vs. 0.76, 0.77, and 0.78, p < 0.001).

Conclusion

GLR might be a useful tool in predicting prognosis for patients with oral cancer.
Temperature influence on NiFeMo nanoparticles magnetic properties and their viability in biomedical applications
Authors: Muchenski Fabio , Gonçalves Jenifer Pendiuk , Ribeiro Yasmin Carla , Franco Célia Regina Cavichiolo , de Oliveira Carolina Camargo , Marcon Bruna Hilzendeger , Robert Anny , de Medeiros Lia Carolina Soares , de Oliveira Ronei Cardoso , de Oliveira Adilson Jesus Aparecido , Mattoso Ney
Published: March 2023

NiFeMo alloy nanoparticles were synthesized by co‐precipitation in the presence of organic additives. Nanoparticles thermal evolution shows that there is a significant increase in the average size (from 28 to 60 nm), consolidating a crystalline structure of the same type as the Ni3Fe phase but with lattice parameter a = 0.362 nm. Measurements of magnetic properties follow this morphological and structural evolution increasing saturation magnetization (Ms) by 578% and reducing remanence magnetization (Mr) by 29%. Cell viability assays on as‐synthesized revealed that nanoparticles (NPs) are not cytotoxic up to a concentration of 0.4 μg/mL for both non‐tumorigenic (fibroblasts and macrophages) and tumor cells (melanoma).
Development and validation of a cancer cachexia risk score for digestive tract cancer patients before abdominal surgery
Authors: Tan Shanjun , Xu Jiahao , Wang Junjie , Zhang Zhige , Li Shuhao , Yan Mingyue , Tang Min , Liu Hao , Zhuang Qiulin , Xi Qiulei , Meng Qinyang , Jiang Yi , Wu Guohao
Published: March 2023

Background

Cancer cachexia is prevalent in digestive tract cancer patients and has significant impacts on prognosis; it is vital to identify individuals who are at risk of cancer cachexia to allow for appropriate evaluation and treatment. This study evaluated whether digestive tract cancer patients with a risk of cancer cachexia and who had a risk of adverse survival could be identified before abdominal surgery.

Methods

This large‐scale cohort study involved patients who underwent abdominal surgery between January 2015 and December 2020 to treat digestive tract cancer. Participants were allocated to the development cohort, the validation cohort, or the application cohort. Univariate and multivariate analyses of the development cohort were performed to detect distinct risk variables for cancer cachexia to create a cancer cachexia risk score. The performance of the risk score across all the three cohorts was assessed through calculating the area under the receiver operating characteristic curve (AUC), as well as calibration and decision curves. We tested how well the score predicted survival outcomes in the application cohort.

Results

A total of 16 264 patients (median 64 years of age; 65.9% male) were included, with 8743 in the development cohort, 5828 in the validation cohort, and 1693 in the application cohort. Seven variables were identified as independent predictive factors and were included in the cancer cachexia risk score: cancer site, cancer stage, time from symptom onset to hospitalization, appetite loss, body mass index, skeletal muscle index, and neutrophil‐lymphocyte ratio. The risk score predicting cancer cachexia owns a good discrimination, with the mean AUC of 0.760 (P < 0.001) in the development cohort, 0.743 (P < 0.001) in the validation cohort, and 0.751 (P < 0.001) in the application cohort, respectively, and had an excellent calibration (all P > 0.05). The decision curve analysis revealed net benefits of the risk score across a range of risk thresholds in the three cohorts. In the application cohort, compared with the high‐risk group, the low‐risk group experienced significantly longer overall survival [hazard ratio (HR) 2.887, P < 0.001] as well as relapse‐free survival (HR 1.482, P = 0.01).

Conclusions

The cancer cachexia risk score constructed and validated demonstrated good performance in identifying those digestive tract cancer patients before abdominal surgery at a higher risk of cancer cachexia and unfavourable survival. This risk score can help clinicians to enhance their capabilities to screen for cancer cachexia, assess patient prognosis, and strengthen early decision‐making on targeted approaches to attune cancer cachexia for digestive tract cancer patients before abdominal surgery.
Metastatic prostate cancer‐derived extracellular vesicles facilitate osteoclastogenesis by transferring the CDCP1 protein
Authors: Urabe Fumihiko , Kosaka Nobuyoshi , Yamamoto Yusuke , Ito Kagenori , Otsuka Kurataka , Soekmadji Carolina , Egawa Shin , Kimura Takahiro , Ochiya Takahiro
Published: March 2023

Bone metastases are still incurable and result in the development of clinical complications and decreased survival for prostate cancer patients. Recently, a number of studies have shown that extracellular vesicles (EVs) play important roles in tumour progression. Here, we show that EVs from metastatic prostate cancer cells promote osteoclast formation in the presence of receptor activator of NF‐κB ligand (RANKL). EV characterization followed by functional siRNA screening identified CUB‐domain containing protein 1 (CDCP1), a transmembrane protein, as an inducer of osteoclastogenesis. Additionally, CDCP1 expression on plasma‐derived EVs was upregulated in bone metastatic prostate cancer patients. Our findings elucidate the effect of EVs from metastatic prostate cancer cells on osteoclast formation, which is promoted by CDCP1 located on EVs. Furthermore, our data suggested that CDCP1 expression on EVs might be useful to detect bone metastasis of prostate cancer.