bluuebunny/crossref_metadata_2025 huggingface dataset:
Social Currency: Analysis of The Economic Potential of Community Development Banks as Instruments of Public Policies in Brazil
Authors: Melquiades Isac , Vieira Naldeir dos Santos
Published: January 2024

Objective: Analyze Community Development Banks and social currencies as instruments of public policies.
 
Theoretical Framework: The study includes theoretical approaches on Community Development Banks and public policies focused on solidarity economy and social currency.
 
Method: The study is a basic, qualitative research grounded in a descriptive approach method, supported by a literature review.
 
Results and conclusion: It was observed that Community Development Banks adopt solidarity financial practices and financial inclusion by facilitating access to credit for individuals in socially vulnerable situations. Social currencies emerge as instruments aiming to energize the local economy through Community Development Banks, promoting the inclusion of marginalized populations. However, there is still much to be explored regarding complementary social currencies, and many municipalities are replicating and implementing this model in their territories to leverage local development. Simultaneously, resources are made available to enhance consumption and income in areas with low levels of credit conditions and financial literacy.
 
Implications of the research: The study emphasizes the need to address Community Development Banks and, particularly, the establishment of public policies for solidarity economy and the creation of social currencies, considering the diversity of each locality.
 
Originality/value: This study offers an original and valuable approach in analyzing Community Development Banks and social currencies as instruments of public policy. It reveals significant insights into the effectiveness of these banks in promoting solidarity financial practices and financial inclusion, especially for those in socially vulnerable situations.
Impact Of Interactive Control In Improving Academics' Performance: Mediating Role Of Fairness
Authors: Yani Indah , Nazaruddin Ietje
Published: January 2024

This study aims to empirically examine the direct and indirect effects of interactive control on performance by analysing the role of justice as an intervening variable. This research uses a survey approach by distributing questionnaires directly or online. The research sample obtained was 383 academics at universities throughout Indonesia. Data analysis was carried out using structural equation modelling. The results showed that interactive control has no direct effect on performance. However, interactive control indirectly affects academic performance through fairness. This suggests the importance of improving fairness in effective performance measurement to improve academic performance. The novelty of this study lies in equity as an intervening variable in the relationship between interactive control and performance. The findings of this study provide practical insights for higher education management to implement an interactive control approach that can increase the sense of fairness towards implementing performance measurement systems to impact academic performance positively.
Congenital nephrotic syndrome secondary to congenital infection: a case report
Authors: Santos Camila , Faria Gabriella , Duarte Marianne , Camara Filipe , Lima Tereza
Published: January 2024

Congenital nephrotic syndrome (CNS) is a rare glomerular disease characterized by massive proteinuria, hypoproteinemia, and generalized edema that manifests in the first 3 months of life. This report describes the case of a patient with congenital nephrotic syndrome secondary to congenital infection in a pediatric patient. The article aims to sensitize pediatricians to the pathology and its etiologies, considering that clinical suspicion allows for better therapeutic management of affected patients and the prevention of potential sequelae.
PENERAPAN MODEL OPEN-ENDED BERBASIS BELAJAR BERMAKNA UNTUK MENINGKATKAN KEMAMPUAN BERPIKIR INOVATIF SISWA
Authors: Sofyan Ahsan , Aznur Utari Putri
Published: January 2024

AbstrakSistem pembelajaran dalam suatu proses belajar yang diduga mampu meningkatkan kemampuan berpikir inovatif siswa adalah implementasi model Open-ended dimana model pembelajaran ini lebih menekankan pada usaha bagaimana siswa sampai pada jawaban daripada ketepatan jawaban semata. Kemampuan berpikir inovatif mampu meningkatkan kemampuan berpikir siswa menjadi lebih kompleks dan mendalam. Dalam mencapai tujuan tersebut maka pendidik harus memfasilitasinya melalui penggunaan model, metode, media, pendekatan, strategi pembelajaran yang bisa menunjang peningkatan kemampuan berpikir siswa. Pengukuran pada penerapan model Open-ended diperoleh rata-rata nilai pretest pada kelas eksperimen sebesar 65,17 sedangkan kelas kontrol memperoleh nilai 73,67. Kemudian setelah dilakukan post test pada kelas eksperimen mengalami peningkatan nilai rata-rata 81,08. Sedangkan kelas kontrol sebesar 78,79 dengan kategori sedang. Aktivitas yang paling menonjol selama proses penerapan model Open-ended yang menggambarkan terciptanya suasana belajar yang berpusat pada siswa, belajar bersama, dan berdiskusi antar siswa menunjukkan adanya peningkatan keaktifan siswa dalam proses pembelajaran.Kata kunci: Berpikir Inovatif; Model Open-ended; Teori Belajar Bermakna AbstractThe learning system in a learning process that is thought to be able to improve students' innovative thinking skills is the implementation of the Open-ended model where this learning model places more emphasis on the effort of how students arrive at answers rather than the mere accuracy of answers. Innovative thinking skills can improve students' thinking skills to become more complex and deep. In achieving these goals, educators must facilitate it through the use of models, methods, media, approaches, and learning strategies that can support the improvement of students' thinking skills. Measurements on the application of the Open-ended model obtained an average pretest value of 65.17 in the experimental class while the control class obtained a value of 73.67. Then after the post-test was carried out in the experimental class it experienced an increase in the average value of 81.08. While the control class was 78.79 in the moderate category. The most prominent activity during the process of implementing the Open-ended model which describes the creation of a student-centered learning atmosphere, learning together, and discussing among students shows an increase in student activity in the learning process.Keywords: Innovative Thinking; Open-ended model; Meaningful Learning Theory
Direct Numerical Simulation of Nonequilibrium Effects on Decaying Isotropic Turbulence
Authors: Kerkar Pawan P. , Ghosh Shankar
Published: January 2024

The Direct Numerical Simulation of decaying isotropic turbulence is performed with nonequilibrium effects. Oxygen is used as the test gas in the simulations. The individual and combined effects of vibrational relaxation and chemical reactions are studied by considering four different simulation cases. The time evolution of mean thermodynamic properties and turbulent statistics is analyzed. Budgets for turbulent kinetic energy and mean internal energy are computed to explain the dynamics of energy exchange associated with different nonequilibrium effects. The time evolution of enstrophy and turbulent length scales is also studied. The dissociation reaction is found to significantly affect the evolution of mean thermodynamic quantities as well as turbulence. Vibrational relaxation is found to significantly affect the flow in the presence of chemical reactions. The effects of changing the initial conditions on the resulting flowfield are analyzed.
Taurine: a supplement for extending life-span and health
Authors: Yadav Vijay Kumar , Singh Parminder , Gollapalli Kishore
Published: January 2024

The world population is aging. In our recent study, we identified that levels of an amino acid called taurine decline during aging. When we used taurine supplementation to reverse this decline, it improved healthspan in worms, mice and monkeys, and lifespan in worms and mice. Thus, taurine deficiency could be a driver of aging and taurine supplementation a potential anti-aging intervention.
PERAN GURU IPS SEBAGAI INFLUENCER DALAM MENINGKATKAN ECOLITERACY PESERTA DIDIK PADA PEMBELAJARAN IPS
Authors: Ramadani Novi Fitria
Published: January 2024

Penelitian ini dilatarbelakangi oleh rendahnya kemampuan kecerdasan ekologi peserta didik kelas VII F SMP Negeri 10 Bandung, keadaan lingkungan kelas yang kotor akibat sampah yang berserakan, boros dalam menggunakan kertas, mengendarai sepeda motor ketika pergi ke sekolah, dan banyaknya peserta didik yang memiliki kebiasaan membeli air minum kemasan dibandingkan dengan membawa botol minum isi ulang dari rumah. Berdasarkan permasalahan tersebut, penelitian ini bertujuan untuk mengembangkan karakter ekoliterasi peserta didik melalui influencer guru dengan memanfaatkan media sosial Instagram untuk menginfluence peserta didik melalui konten-konten ekoliterasi yang dapat mendorong pelibatan karakter ekoliterasi dalam diri peserta didik. Dalam pengembangan karakter ekoliterasi peserta didik, guru pada indikator kompetensi dari The Center for Ecoliteracy yang mencakup tiga aspek yakni aspek pengetahuan, sikap dan keterampilan. Metode yang digunakan dalam penelitian ini adalah penelitian tindakan kelas (PTK) model Kemmis dan Mc Taggart. Desain ini dilakukan dengan empat tahapan, terdiri dari perencanaan, pelaksanaan, observasi dan refleksi. Penelitian ini dilaksanakan dalam tiga siklus. Hasil penelitian menunjukkan penelitian tindakan kelas melalui guru influencer dapat meningkatkan karakter ekoliterasi pada aspek pengetahuan, sikap dan keterampilan peserta didik kelas VII F SMP Negeri 10 Bandung. Desain ini dilakukan dengan empat tahapan, terdiri dari perencanaan, pelaksanaan, observasi dan refleksi. Penelitian ini dilaksanakan dalam tiga siklus. Hasil penelitian menunjukkan penelitian tindakan kelas melalui guru influencer dapat meningkatkan karakter ekoliterasi pada aspek pengetahuan, sikap dan keterampilan peserta didik kelas VII F SMP Negeri 10 Bandung. Desain ini dilakukan dengan empat tahapan, terdiri dari perencanaan, pelaksanaan, observasi dan refleksi. Penelitian ini dilaksanakan dalam tiga siklus. Hasil penelitian menunjukkan penelitian tindakan kelas melalui guru influencer dapat meningkatkan karakter ekoliterasi pada aspek pengetahuan, sikap dan keterampilan peserta didik kelas VII F SMP Negeri 10 Bandung.
Construction of Multi-Scale Dissipative Particle Dynamics (DPD) Models from other Coarse-Grained Models
Authors: Wang Yinhan , Hernandez Rigoberto
Published: January 2024

We present a general scheme for converting coarse grained models into Dissipative Particle Dynamics (DPD) models. We build the corresponding DPD models by anal- ogy with the de novo DPD coarse graining scheme suggested by Groot and Warren (J. Chem. Phys., 1997). Electrostatic interactions between charged DPD particles are represented though the addition of a long-range Slater Coulomb potential as suggested by Gonz ́alez-Melchor et al (J. Chem. Phys 2006). The construction is illustrated by converting MARTINI models for various proteins into a DPD representation, but it not restricted to the usual potential form in the MARTINI model—viz Lennard-Jones potentials. We further extended the DPD scheme away from the typical use of homo- geneous particle sizes, and therefor faithfully representing the variations in the particle sizes seen in the underlying MARTINI model. The accuracy of the resulting construc- tion of our generalized DPD models with respect to several structural observables have been benchmarked favorably against all-atom and MARTINI models for a selected set of peptides and proteins, and variations in the scales of the coarse-graining of the water solvent.
Understanding the resolution and sensitivity in photothermal nanoscale chemical imaging - a point spread function approach
Authors: Zhang Yide , Yilmaz Ufuk , Lukasievicz Gustavo Vinicius Bassi , O’Faolain Liam , Lendl Bernhard , Ramer Georg
Published: January 2024

Atomic force microscopy-infrared spectroscopy (AFM-IR) is a photothermal scanning probe technique that combines nanoscale spatial resolution with the chemical analysis capability of mid-infrared spectroscopy. Using this hybrid technique, chemical identification down to the single molecule level has been demonstrated. However, the mechanism at the heart of AFM-IR, the transduction of local photothermal heating to cantilever deflection, is still not fully understood. Existing physical models only describe this process in few special cases but not in many of the types of sample geometries encountered in the practical use of AFM-IR. In this work an analytical expression for modeling the temperature and photothermal expansion process is introduced, verified with finite element simulations and validated with AFM-IR experiments. This method describes AFM-IR signal amplitudes in vertically and laterally heterogeneous samples and allows us study the effect of position and size of an absorber, laser repetition rate and pulse width on AFM-IR signal amplitudes and spatial resolution. The analytical can be used to identify optimal AFM-IR experimental settings in conventional and advanced AFM-IR modes (e.g., tapping mode, surface sensitive mode). It also paves the way for signal inversion based super-resolution AFM-IR.
PROBLEMS OF HUMAN RESOURCES MANAGEMENT AT INDUSTRIAL ENTERPRISES IN THE POST-WAR PERIOD
Authors: Штепа А.С.
Published: January 2024

The article examines the issues of personnel policy of industrial enterprises in the post-war period. The quantitative and qualitative composition of the personnel in the industrial sector, the number of permanent employees, and the business’s innovative activities have been investigated. It is noted that personnel serves as the foundation for enterprise development, ensuring the stability of industrial enterprises. It has been found that the number of permanent employees in the industrial sector is constantly decreasing, and factors such as the implementation of automated systems and robots replacing human labor, reduction of staff positions by transferring some production to external enterprises, periods of economic crisis, changes in the enterprise’s activities, cost reduction, changes in consumer demand, and demographic decline affect the outflow of personnel. The dependence of industrial workforce on the country’s population is determined. The demographic situation of Ukraine’s population is considered, and the main indicators are calculated, namely: the index of the population’s numerical strength of Ukraine; the index of the working-age population of Ukraine; the index of the number of permanent employees in the industry. The level of workforce turnover is analyzed, the main groups are investigated, and their main reasons for the high level of workforce turnover are identified, based on components such as personnel needs, employer requirements, external factors, aspects, and factors for investigating the quantitative and qualitative composition of employees. The main consequences of high workforce turnover are determined. It is substantiated that in order to prevent a critical situation with personnel issues in the future, a series of preventive measures have been formulated, which need to be implemented soon for each individual industrial enterprise.
University Extension Beyond the Educational Axis: Contributions and Challenges for the Empowerment Process of the Working Classes in Brazil
Authors: Fernandes Yara Dias , De Siqueira Graziana Donata Punzi
Published: January 2024

Objective: The objective of this article is to identify the contributions and challenges of the University Extension to the process of empowerment of the popular classes in Brazil.
 
Theoretical Reference: The authors studied point to the possibility of the University Extension proposing dialogs and transformations between the university and various sectors of society (Soares, 2011). Maciel (2010) clarifies that the University Extension contributes to the approximation of the university with society, which contributes to the democratization of knowledge and development of the critical sense of the population. However, there are still challenges and difficulties regarding the implementation of the extensionist actions, both in relation to the implementation of the actions, as well as the continuity of the proposals developed.
 
Design/Methodology/Approach: We research and study the articles on University Extension, from its genesis to the present day. A survey of articles on education in the capitalist society model was also carried out. The research was carried out from academic sites and periodicals.
 
Results: Although there is a significant contribution of the University Extension to the process of empowerment of the popular classes in Brazil, there are still difficulties as to the continuous and effective execution in this process. Both as regards long-term actions, as well as the impact of the contradictions that exist in this model of society, which still persists inequalities, injustices and arbitrariness.
 
Research, Practical and Social Implications: We suggest researches and in-depth studies on the theme, that make possible strategies for the Extension dialog with the community and be effective in a continuous and democratic manner.
 
Originality/Value: The studies point to significant importance of the University Extension in terms of a dialogical relationship with society, as well as collaboration in the process of empowerment of the popular classes in Brazil.
Um cenário sobre a Educação Estatística na Revista de Ensino de Ciências e Matemática (REnCiMa)
Authors: Coelho Matheus Rodrigues , Barbosa Geovane Carlos , Santos Sidney Silva
Published: January 2024

Este artigo tem por objetivo analisar como se apresentam as pesquisas em Educação Estatística (EE) publicadas na Revista de Ensino de Ciências e Matemática (REnCiMa), no período de 2010 a fevereiro de 2023. Quanto à abordagem metodológica, trata-se de uma pesquisa qualitativa do tipo estado do conhecimento. Os dados foram organizados a partir da seleção de 54 trabalhos formando sete categorias de análise, das quais destacamos: tendências teóricas e didático-pedagógicas; desenvolvimento profissional; políticas públicas educacionais; e sequência didática. Os resultados mostram um aumento na quantidade de trabalhos ao longo do tempo, principalmente, da região Sudeste, bem como um enfoque no conteúdo de Estatística Descritiva; e apontam lacunas urgentes no ensino de combinatória e inferência estatística informal. Por fim, concluímos que a área de EE continua em crescimento, porém, mais pesquisas nessa vertente são necessárias para que as potencialidades e os percursos que ainda faltam trilhar nesse campo sejam identificados.
Diseño de iluminación del Parque del Ferrocarril Miguel Ángel Estrella en Cuenca – Ecuador
Authors: Morocho Chicaiza Walter Geovanny
Published: January 2024

El presente trabajo exhibe una propuesta de Diseño de Iluminación del Parque del Ferrocarril Miguel Ángel Estrella ubicado en la ciudad de Cuenca – Ecuador. Su desarrollo fue basado en un análisis de sus características arquitectónicas, paisajísticas y de la vivencia ciudadana que son esenciales para un parque recreacional de este tipo, la justificación técnica de la propuesta planteada fue apoyada con  criterios, normas y reglamentos de iluminación vigentes en el Ecuador, así también de algunas recomendaciones de normas y  guías de iluminación internacionales, esta  última dando énfasis en el aspecto cualitativo (estético). Inicialmente se  conceptualizo la idea de  iluminación del parque,  trayendo a colación  su marco histórico, su gente, ubicación, localidad, flora y fauna del sector, dicho trabajo nos  ayudó a definir parámetros muy importantes a  ser considerados dentro de la propuesta, como: las alturas  de los puntos de luz, la temperatura de color, el índice de reproducción cromática (CRI), diseños y  modelos de los luminarios, etc. Una vez implementado los criterios  y con la ayuda de software de rasterización como  Revit, SketchUp y DiaLux evo 10.1 se  procedió a modelar y a calcular todos los espacios que componen elparque, valorando así parámetros como  la iluminancia, luminancia y uniformidad que fueron  planteados en la fase inicial del sistema de alumbrado ornamental propuesto. Finalmente, se realizó una  valoración económica  con  el fin de analizar la  vialidad del proyecto.
Análisis de riesgo de la declaración de conformidad de la potencia de luminarias a un nivel determinado de confianza
Authors: Juiña Daniela , Silva Byron , Velásquez Carlos
Published: January 2024

El presente trabajo ha estudiado el análisis de riesgo probabilístico al momento de efectuar una declaración de conformidad sobre las bondades técnicas de una luminaria. Las luminarias bajo prueba son luminarias LED, dado que la tecnología LED tiene un creciente desarrollo y que actualmente estas luminarias son las más utilizadas para el alumbrado público a nivel mundial. Existen gran cantidad de fabricantes y por tanto, es necesario verificar la calidad de las luminarias que se comercializan; para lo cual, se requiere que algún organismo evaluador de la conformidad (OEC) certifique que las bondades técnicas de las luminarias cumplen con normativas. Para este estudio, el parámetro a analizar es la potencia, el OEC es un laboratorio de ensayos que se encuentra acreditado con la norma ISO/IEC 17025, y bajo la cual realiza la declaración de conformidad; el valor de potencia se obtiene durante la ejecución de ensayos de matriz de intensidad luminosa. Las medidas de potencia se han evaluado bajo una estadística paramétrica y se ha obtenido que para niveles de confianza inferiores a 99,99% la potencia registrada de la luminaria es conforme, y para niveles de confianza superiores a 99,998% el resultado es no conforme con el esquema experimental utilizado.
Soluciones digitales de inclusión educativa para personas con discapacidad visual
Authors: Bermejo Marlon , Leon Pacheco Diego , Minchala González Jacobo , Lema Lema Edwin
Published: January 2024

En este estudio realizado se define lo que se considera como discapacidad visual y cuáles son sus tipos, características, causas y cuantas personas padecen de esto en todo el mundo según la Organización mundial de la salud y dentro del Ecuador según la CONADIS nos aporta un total de 11,47% de la población que sufre esta discapacidad, enfocándonos en cuales son los impactos que tienen las personas cuando deciden estudiar una educación superior y como el avance de las tecnologías pueden aportar una ayuda mediante el uso de herramientas por ello este trabajo se centra dentro de la Universidad Católica de Cuenca identificando estudiantes que tengan casos visuales dentro de la institución y realizando métodos de recolección de información como entrevistas, observación, revisión literarias y de documentación tomando en cuenta los estudios previos en otros países como Colombia, Venezuela y como las TICS ha llevado a un desenvolvimiento dentro de su estudios universitarios  y con la sociedad tomando en cuenta las herramientas y realizando comparativas para dar como resultado una recomendación que les pueda servir de apoyo ya que con la ayuda de las nuevas tecnologías se puede tener una mayor interacción entre estudiantes y profesores así reforzando su aprendizaje.
A Critical Analysis of the General Principles of Sentencing under the Criminal Law Doctrine and Their Application by the Supreme Court of the Russian Federation
Authors: Safin L. R.
Published: January 2024

This article highlights the need to enhance the procedures for determining guilt through criminal law. The study is based on a careful analysis of the legal standards laid down in the Criminal Code of the Russian Federation and key academic sources of the Russian criminal law. Potential solutions were offered to address the contentious matters within the criminal law doctrine. According to the obtained results, when the Plenum of the Supreme Court of the Russian Federation voices its stance on a number of issues regarding sentencing, it occasionally surpasses its powers conferred by the Constitution of the Russian Federation. It was established that the general principles of sentencing are such regulations that apply to all types of offenses, regardless of the type, nature, or gravity of the crime committed. The scope of these regulations extends beyond Article 60 of the Criminal Code of the Russian Federation and specifies its provisions. Another batch of standards includes regulations governing the rules and procedures for imposing certain types of penalties, as well as their specificity for certain criminal behaviors.
Evrişimli sinir ağları kullanılarak ince kesit görüntülerden hidrotermal alterasyon tespiti
Authors: ÇENET Rıza , ÜNSAL Emre , CANBAZ Oktay
Published: January 2024

Hidrotermal alterasyon, cevher oluşturan hidrotermal sıcak sulu çözeltilerin etkisiyle yan kayaçlarda meydana gelen mineralojik, kimyasal ve fiziksel değişimler olup değerli maden arama araştırmalarında kullanılan önemli bir jeolojik özelliktir. Kayaçlardan hazırlanan ince kesitler kullanılarak alterasyon türlerinin belirlenmesi ve sınıflandırılması jeolojik çalışmaların önemli bir aşaması olup uzmanlar tarafından yürütülmektedir. Bu araştırma, en yaygın beş hidrotermal alterasyon türünü tanımlamak ve sınıflandırmak için oluşturulan bir derin öğrenme ağı yapısına odaklanmaktadır. Saha çalışmalarında toplanan temsili kayaç örneklerine ait ince kesitlerden her sınıfa ait 500 adet olmak üzere toplamda 2500 mikroskop görüntüsü bulunduran bir veri seti oluşturulmuştur. Bu veri setinin, %70’i ağın eğitilmesinde, %20’si ağın test edilmesinde ve %10’u ağın geçerliliğinin ölçülmesinde kullanılmıştır. CNN tabanlı oluşturulmuş derin öğrenme ağında, dört katman bulunmaktadır. Bu ağ, Adam, Rmsprop ve SGD optimizasyon fonksiyonları kullanılarak eğitilmiş ve sonuçları karşılaştırılmıştır. Adam ve Sgd fonksiyonları %96 doğru sınıflandırma yaparak, en başarılı sınıflandırmayı gerçekleştirmiştir. Yüksek seviyedeki bu sınıflandırma, hidrotermal alterasyon tiplerinin belirlenmesinde, oluşturulan derin öğrenme ağ modelinin kullanılabileceğini göstermektedir.
Peer-to-Peer Data Transfer Evaluation in SmartSSD-based Multi-devices System
Authors: Daoud Luka , Sun Gongjin , Huen Hingkwan
Published: January 2024

Due to the growing demands on big data, data centers are expanding their systems to improve their capacity and capability. Common expansion techniques are: adding more memories, increasing the storage capacity, and attaching hardware accelerator devices. Benefit aside, such expansion puts a higher demand on the host system due to the increasing amount of data movements. It quickly consumes the available system bandwidth and sets a heavy burden on data transfers among the devices. To ease this situation, recent advanced solutions have appeared to optimize the data flow. These include peer-to-peer data transfer, allowing direct device-to-device data exchange without involving host memory. This paper evaluates the system performance for peer-to-peer (P2P) data transfer among connected devices. The results show that P2P data transfer between two devices in the system is 2x - 6x faster than non-P2P cases via bypassing the host memory. Not only does it reduce the memory occupancy but also the system power cost.
Sentinel lymph node biopsy versus no axillary surgery in early breast cancer clinically and ultrasonographically node-negative: A prospective randomized controlled trial – venus trial early results after 3.5 years of study inception
Authors: Araújo Danielle Cristina Miyamoto , Duarte Giuliano Mendes , Hubert Maria Beatriz de Paula Leite Kraft Enz , Jales Rodrigo Menezes , Sarian Luis Otávio , Pessoa Eduardo Carvalho , Oliveira Júnior Idam de , Group Venus Trial
Published: January 2024

Objective: The VENUS trial is an ongoing prospective, multi-center, non-inferiority randomized controlled clinical trial aimed at comparing the disease-free and overall survival of T1-2 N0 M0 breast cancer patients subjected to either (a) sentinel lymph node (group sentinel) or (b) no axillary surgery (group no-sentinel). This is a partial report on the initial data collected 3.5 years after the trial started. VENUS differs from previous similar trials in that women undergoing mastectomy and neoadjuvant chemotherapy are accepted. Methodology: The protocol was approved by the local research ethics committee (CAAE: 068051 18.2.0000.5404). Initial axillary status was ascertained through physical examination and axillary ultrasound. Randomization is being stratified by age and clinical tumor size. Secondary endpoints include regional recurrence-free survival, axillary recurrence rate, axillary morbidity rate, ultrasound accuracy, and cost-effectiveness. The sample size was estimated at 800 participants. Primary and secondary endpoints will be reported after 5 years of follow-up of the completed cohorts. VENUS trial is registered in Clinical Trials (Identifier: NCT05315154) and ReBEC (Identifier: RBR-8g6jbf). Results: As of February 2023, 176 patients were enrolled and 156 were randomized to the sentinel (84 patients) and no-sentinel (72 patients) groups. The current mean follow-up time is 18.57 (+8.52) months. Patients are statistically evenly distributed across study groups regarding age and molecular subtype. Sentinel lymph node positivity in the sentinel group was 17.8% (1.19% isolated tumor cells, 3.57% micrometastasis, 11.90% 1–3 macrometastasis, and 1.19% > 4 macrometastasis). There were no axillary recurrences in both groups. Conclusion: Until now, with nearly 20% of the trial completed, VENUS showed no significant difference regarding its posted objectives in women undergoing or not sentinel lymph node dissection.
Oncological outcomes of selective axillary dissection using carbon as a marker
Authors: Budel Lucas Roskamp , Spautz Cleverton César , Louveira Maria Helena , Cavalcanti Teresa Cristina Santos , Gasperin Jr Plinio , Fornazari Alessandra Cordeiro , Nissen Leonardo Paese , Budel Vinicisu Milani
Published: January 2024

Objective: The use of axillary marking before neoadjuvant systemic therapy (NST) is a field of controversy in patients with positive lymph nodes (LNs). Several methods were tested leading to a reduction in the false negative rate compared with the sentinel lymph node (SLN), adding precision. The aim of this study is to evaluate oncological outcomes in patients undergoing selective axillary dissection with pre-NST marking with 4% carbon. Methodology: A prospective study was carried out in patients with cT1–T4 and cN1–N2 breast cancer who underwent analysis of suspected LNs and concomitant marking with 4% carbon. After NST, the marked LNs were identified and resected associated with SLN biopsy. The oncological outcomes identified were overall survival (OS), specific survival (SE), distant disease-free survival (DDFS), axillary recurrence (AR), and local recurrence. Results: A total of 168 patients were analyzed over a median time of 49 months. Axillary dissection was omitted in 89 (50.6%) cases. Out of 168 cases, 5 (2.9%) had AR. There was a significant association between axillary dissection and AR (0 vs. 6% p=0.012). The DDFS was 140/168 (83.3%), SG 158/168 (94%), and SE 158/163 (96.9%). Conclusion: The use of carbon as a marker in selective axillary dissection is a reliable, low-cost, and easy-to-perform material. Among the oncological events, AR should not be used for post-downstaging axillary evaluation analysis, as it is a rare event and is not necessarily related to OS or DDFS.
What happens in residual disease after neoadjuvant chemotherapy? Efficacy of a novel in vitro breast cancer chemoresistance platform to demonstrate high resistance to drugs
Authors: Lichtenfels Martina , Fontana Vivian , Nyland Francine Hickmann , Marques Bianca Silva , Schorr Mário Casales , Marcolin Júlia Caroline , Farias Caroline Brunetto de , Pedrini José Luiz
Published: January 2024

Objective: Our preliminary study aimed to validate the efficacy of a novel in vitro chemoresistance platform to demonstrate tumor resistance in residual disease after neoadjuvant treatment for breast cancer. Methodology: Patients with invasive BC who presented residual disease after neoadjuvant chemotherapy (NACT) were included. Fresh tumor samples were collected during surgery and dissociated to obtain the tumor cells. The tumor cells were cultured in the chemoresistance platform with doxorubicin, epirubicin, paclitaxel, docetaxel, and cyclophosphamide, and after 72 h, cell viability was evaluated. The test result is defined based on cell viability as low (60%) resistance. Results: Samples from 20 patients with residual disease after NACT were tested in the chemoresistance platform. Regarding molecular subtypes: 9 tumors were triple-negative (45%), 6 luminal (30%), 4 LuminalHER2 (20%), and 1 HER2 (5%). A total of 16 (80%) patients responded partially to NACT, and 4 (20%) presented disease progression. Most (80%) of the patients used ACT (doxorubicin + cyclophosphamide + paclitaxel) chemotherapy regimen, 10% only paclitaxel, and 10% doxorubicin plus cyclophosphamide. The chemoresistance platform demonstrated that tumors treated with doxorubicin, paclitaxel, and cyclophosphamide in neoadjuvant setting presented high rates of resistance to the drugs (94.7% showed high resistance to paclitaxel, 58% to doxorubicin, and 52.6% to cyclophosphamide). In addition, we investigate if the tumor becomes more resistant to drugs from the same class (taxanes and adriamycin) of the treatment already used by the patients and evidenced 93.7% of high resistance to docetaxel and 50% to epirubicin. Conclusion: This preliminary finding highlighted the efficacy of the in vitro chemoresistance platform to demonstrate the acquisition of resistance during NACT and suggested a role of acquired resistance in the worse prognosis of patients with residual disease after NACT.
Empowering Teachers: Multicultural Social and Emotional Learning (MSEL) Among Arab Minority Teachers
Authors: Soffer-Vital Shira , Finkelstein Idit
Published: January 2024

Teachers are the professionals at the forefront in the implementation of the educational enterprise, yet it is widely known that despite being surrounded by learners, they are oftentimes isolated and lonely individuals.  The plight of teachers, particularly ones who are minorities, is critical to the success of schooling. To address this problem, schools have been seeking to pay closer attention to the holistic characteristics of schooling in general and how to ameliorate teacher conditions in particular. In recent years, the onset of the COVID-19 pandemic has heightened concern for the overall well-being of teachers, for enhancing their ability to cope with stress, depression, and loneliness, and for empowering resilience. In this sense, social and emotional learning (SEL) can serve as a main component in addressing these issues. SEL of teachers plays a central role in their daily practices and functioning. This study was devised and aimed at investigating the role of SEL as it impinges on teachers using a quantitative research study. The major hypothesis of this research involving SEL is that cultural empathy is the key linking mediator between both social competence and emotional stability of teachers and their self-efficacy for learning. To verify these interactions, questionnaires were distributed and completed by 415 teachers from the Arab Muslim sector, a minority population in Israel potentially vulnerable to the above-mentioned alienating effects of teaching. Our results did show a significant interaction between social competence and cultural empathy on self-efficacy for learning.  Additionally, our results also detected a significant interaction between emotional stability and cultural empathy on self-efficacy for learning. This research supports the proof of concept that the potential of SEL to foster increased achievement and equity in multicultural schools may be fulfilled provided that there is a greater effort to integrate the ideals of SEL into school practices. Finally, we discuss the importance of promoting emotional stability, social competence, and cultural empathy in schools by fostering social inclusion.
Upaya Peningkatan Pengetahuan dan Sikap Remaja Putri Tentang Keputihan Melalui Pendidikan Kesehatan dengan Media Komik Elektronik dan Leaflet di SMA N 3 dan SMA N 9 Bengkulu Selatan
Authors: Magrita Nova , Sunartono  , Mediastuti Fitriani
Published: January 2024

Menurut World Health Organization (WHO), keputihan dialami oleh hampir seluruh wanita di dunia, 60% pada usia 15-22 tahun dan 40% pada usia 23-45 tahun. Sebanyak 75% wanita Indonesia pernah mengalami keputihan dengan kejadian keputihan 50% pada remaja dan 25% pada wanita usia subur. Menganalisis pengaruh pendidikan kesehatan melalui komik elektronik dan leaflet untuk meningkatkan pengetahuan dan sikap remaja putri tentang keputihan di SMAN 3 dan SMAN 9 Bengkulu Selatan. Penelitian quasi experiment dengan desain pre test-post test with control group. Populasi siswi kelas XI sebanyak 65 orang di SMAN 3 dan 90 orang di SMAN 9 Bengkulu Selatan, menggunakan metode purposive sampling, diperoleh 41 responden pada kelompok eksperimen dan 41 responden pada kelompok kontrol. Hasil uji independent samples t-test menunjukkan nilai p sebesar 0,008 artinya ada perbedaan rata-rata pengetahuan kelompok eksperimen dan kontrol artinya ada peningkatan pengetahuan remaja putri tentang keputihan setelah dilakukan intervensi. Pada variabel sikap nilai p sebesar 0,000. maka ada perbedaan rata-rata sikap kelompok eksperimen dan kontrol artinya ada peningkatan sikap remaja putri tentang keputihan setelah dilakukan intervensi. Media komik elektronik dan leaflet berpengaruh untuk meningkatkan pengetahuan dan sikap remaja putri tentang keputihan di SMAN 3 dan SMAN 9 Bengkulu Selatan.
Studi Kasus: Foot Massage Minyak Zaitun untuk Fatigue pada Pasien Hemodialisis
Authors: Melati Nimsi , Retang Yohana Rambu Anarara , Kristiningsih Agustin Eka
Published: January 2024

Pasien gagal ginjal kronik memerlukan terapi dialisis, salah satunya hemodialisis.  Fatigue merupakan efek samping hemodialisis. 71-92% pasien mengalami fatigue ketika hemodialisis berlangsung. Fatigue disebabkan karena lamanya proses hemodialisis, anemia, sindrom uremia, dan penurunan tekanan darah akibat efek hemodialisis. Fatigue menyebabkan penurunan konsentrasi, gangguan emosional, dan gangguan tidur yang dapat mempengaruhi aktivitas sehari-hari dan kualitas hidup. Tujuan penelitian ini mengetahui pengaruh foot massage untuk menurunkan fatigue pada pasien hemodialisisMetode penelitian menggunakan deskriptif kuantitatif dengan studi kasus. Teknik pengambilan sampel menggunakan purposive sampling dengan jumlah sampel satu orang. Alat ukur penelitian menggunakan Functional Assessment Chronic Illness Therapy (FACIT) Fatigue Scale. Pada pasien intervensi setelah diberikan tiga kali intervensi, setiap intervensi dilakukan selama 15 menit saat intrahemodialisis. Hasil penelitian menunjukkan terjadi penurunan fatigue dari tingkat sedang ke tingkat ringan yang berarti foot massage mampu menurunkan fatigue pada pasien gagal ginjal kronik yang sedang menjalani hemodialisis. Hal ini dikarenakan foot massage mampu meningkatkan sirkulasi darah yang dapat meningkatkan suplai oksigen dan energi ke tubuh serta mempercepat pembuangan sisa metabolisme dari tubuh, sehingga keluhan fatigue berkurang
Spiritual Emotional Freedom Technique (SEFT) untuk Menurunkan Tekanan Darah pada Penderita Hipertensi: Tinjauan Sistematis
Authors: Jumain  , Agustinus Talindong  , Wahyu  , Parmi  , Mutmainnah HS
Published: January 2024

Spritual Emotional Freedom Technique (SEFT) merupakan tehnik yang menggabungkan teknik sistem tubuh dan terapi spiritual menggunakan menekan pada titik-titik tertentu pada tubuh. SEFT termasuk bantuan individu bebas dari tekanan emosional (energi negatif), yang merupakan penyebab meningkatkan tekanan darah pada pasien hipepertensi. Hipertensi adalah suatu keadaan terjadi peningkatan tekanan darah dengan ditandai gejala yang akan berlanjut ke suatu organ target seperti stroke, penyakit jantung coroner dan hipertrofi ventrikel kanan. Tinjauan sistematis ini bertujuan meniliai efek yang ditimbulkan dari Spritual Emotional Freedom Technique (SEFT) dengan adanya hasil terjadi penurunan tekanan darah pada penderita hipertensi. Menggunakan tinjauan sistematis dengan memanfaatkan empat database elektronik untuk pencarian: Pubmed, Science Direct, Google Scholar dan Portal Garuda. Studi Randomized Control Trial dan Quasy Experimen yang melakukan penelitian mengenai SEFTdigunakan sebagai kriteria inklusi. Tinjauan sistematis ini terdapat sepuluh penelitian memenuhi kriteria untuk ulasan teks lengkap. Temuan dalam penelitian ini menunjukkan bahwa SEFT sangat efektif menurunkan tekanan darah pada penderita hipertensi. Intervensi non farmakologis yaitu SEFT (Spiritual Emotional Freedom Technique) berdampak baik dilakukan pada penyakit hipertensi untuk penurunan tekanan darah. Sehingga dapat dijadikan sebagai terapi komplementer yang baik bagi penderita hipertensi.
Investigation of Encountered Problems After Laparoscopic Surgery in Children
Authors: CAKMAK Aynur , VURAL Fatma
Published: January 2024

Aim: This study was planned to determine the problems and affecting factors that children encounter at hospital and at home after laparoscopic surgery.

Materials and Methods: This study was conducted in accordance with the descriptive cross-sectional study type in order to determine the post-operative conditions in hospital and home problems and factors affecting the operation of the study. The study was carried out on the patients of pediatric service of whom had laparoscopic surgery. Pre-operative and post-operative descriptive features form, which was developed according to literature by researchers as data collection tool, was collected by using a diagnosis form for problems occurred at home after discharge and for problems occurred in hospital after surgery.

Results: It was found in the study that 54.5% of the children were male, 90.9% were gastrointestinal system surgeons and 65.4% were acute appendectomies. It was determined that most of the problems the children lived in hospital and at home was pain.

Conclusion: This study will contribute to the planning of nursing interventions that will be useful for the identification, prevention and early identification of the problems that children experience both at home and in the hospital, after the surgery, and to determine the maintenance criteria.
Die schwangere Psychoanalytikerin
Authors: Hajek Gisela
Published: January 2024

Durch eine Schwangerschaft der Psychoanalytikerin verändern sich das Setting und die Dynamiken innerhalb der Therapie. Die spezifischen, häufig intensiven Auswirkungen dieser Veränderungen für Psychoanalytikerin und Patient*in können konstruktiv nutzbar werden, wenn der Psychoanalytikerin die Möglichkeiten und Bedeutungen dieser Veränderungen bewusst sind. Dennoch haben Schwangerschaft und eine eigenständige weibliche Entwicklungstheorie bislang wenig Eingang in psychoanalytische Theorien gefunden. Gisela Hajek veranschaulicht, was es bedeutet, als Psychoanalytikerin schwanger zu sein. Der Tradition psychoanalytischer Theoriebildung folgend zeigt sie anhand des Zustandes von Schwangerschaft auf, wie die Bedeutung weiblicher Potenz auf theoretischer Ebene denkbar und auf praktisch-therapeutischer Ebene nutzbar werden kann. Mit Die schwangere Psychoanalytikerin leistet sie einen enttabuisierenden und aufklärerischen Beitrag zur feministischen Psychoanalyse.
SOSIALISASI PROFESI AKUNTAN DAN KELAS INTERNASIONAL AKUNTANSI PADA SEKOLAH MENENGAH ATAS DI LOMBOK TIMUR
Authors: Rizki Novia
Published: January 2024

Accounting is a science that studies the preparation of financial reports and various types of financial analysis, while an accountant is a profession that carries out accounting. The accounting profession is very diverse, ranging from public accountants, corporate accountants, educator accountants, to government accountants. Each type of accounting profession has different qualifications, duties and responsibilities. For high school students, knowledge about the accounting profession is still very minimal, so socialization is needed regarding this matter. This community service activity is in the form of socialization which aims to better understand the various accounting professions so that they can strengthen them to continue studying in the accounting department.In addition to this socialization, material about international accounting classes was added, especially at the University of Mataram. The methods for implementing these service activities include preparation, preparation of materials and media, socialization, and post-socialization by evaluating activities. A positive response was given by socialization participants who were students majoring in Social Sciences who were in class XII.
Influence of Anodal tDCS on the Brain Functional Networks and Muscle Synergy of Hand Movements
Authors: Chen Sijia , Luo Zhizeng , Lai Jianjun
Published: January 2024

Background: Transcranial direct current stimulation (tDCS) is a non-invasive technique that has demonstrated potential in modulating cortical neuron excitability. The objective of this paper is to investigate the effects of tDCS on characteristic parameters of brain functional networks and muscle synergy, as well as to explore its potential for enhancing motor performance. Methods: By applying different durations of tDCS on the motor cortex of the brain, the 32-lead electroencephalogram (EEG) of the cerebral cortex and 4-lead electromyography (EMG) signals of the right forearm were collected for 4 typical hand movements which are commonly used in rehabilitation training, including right-hand finger flexion, finger extension, wrist flexion, and wrist extension. Results: The study showed that tDCS can enhance the brain’s electrical activity in the beta band of the C3 node of the cerebral cortex during hand movements. Furthermore, the structure of muscle synergy remains unaltered; however, the associated muscle activity is amplified (p < 0.05). Conclusions: Based on the study results, it can be inferred that tDCS enhances the control strength between the motor area of the cerebral cortex and the muscles during hand movements.
Storytelling: Generational Losses in Translation of IDEA Concepts and Terminologies
Authors: Sprinkle Therese , Yawson Robert
Published: January 2024

  

Through the use of generational storytelling, our multi-layered exercise is designed to bridge gaps in the inclusion, diversity, equity and accessibility conversations. In doing so, students become aware of all that has been gained, and begin planning for the next phase of acceptance and inclusion. We begin by challenging the students on statements made about inclusion and equity from readings and textbooks. Stories are then shared from across generations to provide the IDEA definitions each different working generation has used. Finally, students are challenged to craft a path forward, to identify what steps are needed next. 