bluuebunny/crossref_metadata_2025 huggingface dataset:
African languages as medium of assessment in the teaching of indigenous languages in higher education: a paradigm shift
Authors: Viriri Eunitah , Ndimande-Hlongwa Nobuhle
Published: December 2023

This study was a call for a paradigm shift in the language of assessment for indigenous languages in higher education. It challenged the continued use of English in Teaching Practice supervision at one Zimbabwean State University whose language policy emphasises the teaching of African languages through the respective languages. It sought to establish challenges encountered by students studying African languages who are taught and examined through indigenous languages in all the other modules except for Teaching Practice. This research used the qualitative paradigm where ten randomly selected student teachers practicing ChiShona were interviewed together with two section coordinators. Document analysis was also used to analyse assessment reports. From the study, it was established that the English instruments were designed to accommodate supervisors who are not indigenous languages specialists, there was confusion among supervisors and supervisees on translating indigenous languages on documents and used during lesson delivery to English and vice versa and the student teachers’ potentials were limited due to difficulties in interpreting the instrument. The study concluded that the use of English in teaching practice for African languages was not effective as it compromised quality in both practice and supervision. It, therefore, recommends the use of assessment instruments prepared in indigenous languages.
Challenges faced by intermediate phase isiZulu teachers in teaching inclusive reading
Authors: Ntshangase Chief
Published: December 2023

Despite several interventions put in place to alleviate the reading crisis in South African education, many teachers still experience challenges in teaching reading comprehension. The situation is even more dire with regards to teaching inclusive reading to at-risk readers in mainstream schools in under-resourced settings. Very few studies have been conducted to investigate the pedagogical strategies in teaching inclusive reading in the intermediate phase (IP) isiZulu classrooms. This study aims to investigate the pedagogical challenges faced by IP isiZulu teachers who are teaching reading comprehension skills to at-risk readers in the mainstream schools of uMkhanyakude district, in the Northern part of KwaZulu-Natal province. This qualitative study is guided by the Word Learning Theory which posits that reading instruction should enhance learners’ knowledge of the alphabet and high-frequency words. Data were collected through non-participant classroom observations and interviews with 10 IP isiZulu teachers based in uMkhanyakude district. The qualitative data were analysed by the researcher through coded thematic analysis. The units of analysis in this study are IP teachers’ pedagogic strategies in teaching inclusive reading. The findings indicate that IP isiZulu teachers struggle to organise meaningful and cohesive reading strategies. Strategies employed are not structured to address specific reading challenges and consequently at-risk readers in mainstream schools remain inadequately catered for. This study will contribute to the body of knowledge related to the pedagogical strategies best suited for developing inclusive reading.
The Trend of Plastic Recycling Policies in Japan on the Current Legal Regulation of Transboundary Movements of Plastic Waste
Authors: Yang Yunhan
Published: December 2023

Since China’s import ban on solid waste in 2017 and the entry into force of “Plastic Amendment” to the Basel Convention, global plastic waste trading has entered a new historical stage that transboundary movements of plastic waste is no longer regarded as a wise approach for many developed countries. Due to the fact that China, a traditional plastic-importing country, no longer accepts plastic waste after 2021, and the strict regulations on cross-border plastic transactions under the amendment to the Basel Convention, the circulation of plastic waste is increasingly restricted, making it imperative for the world to build a new plastic disposal system to deal with the immediate crisis. As a traditional plastic-export country in Asia, Japan faces domestic plastic overstocking crisis as well. However, as a well-known environmentally-friendly country, Japan’s new policies and legal perfection implemented thereafter have triggered concerns. Regulations through the whole process including production, use, recycling of plastic have clearly specified the responsibilities of main bodies, and the macro control of product production standards sets a unified supervision system at the national level. The valuable experience of this “Japanese Model” can provide some references for China’s future improvements of domestic plastic waste management.
Razvoj slovenske prisotnosti v goriškem javnem prostoru pred prvo svetovno vojno
Authors: Devetak Robert
Published: December 2023

Prispevek obravnava razvoj slovenske prisotnosti v javnem prostoru mesta Gorice – večnarodnostnem središču dežele Goriške in Gradiške na prehodu iz 19. v 20. stoletje. Slovenska strategija vstopa v mestni javni prostor, kjer je imela primat italijanska mestna skupnost, se je usmerila v krepitev gospodarske in politične moči v mestu. V praksi se je to izkazovalo z vse večjim številom slovenskih gospodarskih subjektov, različnih društev in organizacij ter nakupi in izgradnjami reprezentativnih zgradb. Vrhunec slovenskega prodora v središče mesta je predstavljala izgradnja Trgovskega doma leta 1904.
Historical Science in Chains: The Impact of the Bilateral Agreement Between Skopje and Soﬁa on Freedom of Academic Work
Authors: Vankovska Biljana
Published: December 2023

The article focuses on the impact of the bila- teral Treaty between Skopje and Soﬁa (2017) on academic freedom of history research in N. Macedonia. It starts with the elaboration of the wider problem of the marriage of convenience between politics and academia, followed by que- stioning if historical research is possible under the grip of geopolitics. The central part argues that the current political and legal framework curtail the freedom of research for the sake of the ‘greater good’. To sum up, the Macedonian historiography is subject to unconcealed external control that challenges its existence as a genuine academic discipline.
Antibiotic Susceptibility Patterns of Gram-Negative Anaerobic Bacteria Isolated from Clinical Samples
Authors: BİLDEN Alican , ATMACA Selahattin , ÖZCAN Nida
Published: December 2023

Amaç: Anaerop bakteriler vücudun normal flora elemanı olmasına karşın, bağışıklık sisteminin zayıflamasıyla enfeksiyona neden olabilirler. Bu bakterilerin izolasyonları ve identifikasyonları güç olduğu için çoğu laboratuvarda yapılmamaktadır. Bu sebeple çoğu zaman anaerop bakteriler göz ardı edilebilmektedir. Bunun sonucu olarak da gelişen antibiyotik direnç durumları tespit edilememektedir. Bizim bu çalışmadaki amacımız, anaerop bakterilerin antibiyotik direnç profillerinin bilinmesinin tedavinin seyri açısından gerekli olduğunu ve belirli periyodlarda antibiyotik duyarlılık testlerinin yapılması gerektiğini ortaya koymaktır.
Metod: Çalışmaya, Dicle Üniversitesi Tıp Fakültesi Tıbbi Mikrobiyoloji AD. Bakteriyoloji/Kültür laboratuvarına, çeşitli klinik birimlerden anaerop kültür istemiyle gönderilmiş 372 numune dahil edilmiştir. Bu numuneler, ilk olarak bakteri izolasyonu için Brucella kanlı agara ekildi. İzole edilen bakterilerin identifikasyonları MALDI-TOF MS ile yapıldıktan sonra antimikrobiyal duyarlılık profillerinin belirlenmesi için E – test yöntemi kullanıldı.
Bulgular: İzole edilen 17 Bacterioides türünde antimikrobiyal direncin en yüksek olduğu antibiyotikler sırasıyla % 100 oranında penisilin (P), % 41,2 oranında klindamisin (CM) ve % 35,3 oranında ise amoksisillin-klavulanik asid (AMC) olarak belirlendi. İzole edilen 22 Prevotella türünde ise antimikrobiyal direncin en yüksek olduğu antibiyotikler % 45,5 oranında penisilin (P) ve % 27,3 oranında moksifloksasin (MX) olarak belirlendi. Yine izole edilen 1 Dialister pneumosintes bakterisinde sadece metronidazol (MZ) direnci gözlemlenirken, 1 Veillonella parvula bakterisinde ise penisilin (P), imipenem (IP) ve piperasillin-tazobaktam (TPZ) antibiyotiklerine karşı direnç gözlemlenmiştir. Son olarak da izole edilen 4 Fusobacterium türünde ise hiçbir antibiyotiğe karşı direnç gözlemlenmemiştir.
Sonuç: Çalışmamızda izole edilen Gram-negatif anaerop bakterilerin büyük çoğunluğunun penisilin, klindamisin, moksifloksasin, metronidazol ve amoksisillin-klavulanik aside karşı bir direnç geliştirdiği veya bu antibiyotiklere karşı artan bir dirence sahip olduğu görülmüştür.
Anahtar Sözcükler: Gram-Negatif Anaerop Bakteriler, E-Test, MIC, MALDI-TOF MS
The Effect of Arm Length and Hand Quickness on Shot Accuracy Rates in Basketball Players
Authors: GÖZAÇIK Yusuf
Published: December 2023

Objective: The effects of various physical and motor skills on the performance of basketball players are well known. Scoring through shooting is one of the most commonly used techniques in basketball. This study analysed the connection between arm length and hand quickness among basketball players and their shooting accuracy.
Method: The study was carried out on 17 male and 16 female athletes, aged 18-25 years, who played basketball in university teams in 2021-2022 and had at least 5 years of eligibility. The athletes' height, body weight and full length of each athlete's arm were measured. The AAHPERD Basketball Speed Spot Shooting Test was used to measure the shooting accuracy of the athletes. For the athletes' hand quickness, Hand Quickness Test (Touching Discs) was used.
Results: Results indicated a moderate positive correlation between hand quickness score and shot accuracy score among male athletes, but this relationship was not statistically significant. However, a moderate positive and statistically significant correlation was found between hand quickness score and shot accuracy score among female athletes. Among all athletes, there was a positive and statistically significant correlation between arm length, hand quickness speed, and shot accuracy score.
Conclusion: The study's findings indicated that shooting accuracy was also impacted by arm length, with particular emphasis on hand quickness of the athletes.
KẾT QUẢ PHẪU THUẬT KẾT XƯƠNG NẸP KHÓA ĐIỀU TRỊ GÃY XƯƠNG GÓT PHẠM KHỚP
Authors: Nguyễn Năng Giỏi , Nguyễn Văn Lượng
Published: December 2023

Mục tiêu: Đánh giá kết quả xa kết xương nẹp khóa gãy kín xương gót phạm khớp. Phương pháp nghiên cứu: Nghiên cứu hồi cứu và mô tả, không nhóm chứng trên 56 bệnh nhân (BN) gãy kín xương gót phạm khớp được kết xương nẹp khóa, tại Bệnh viện Trung ương Quân đội (BVTWQĐ) 108, trong thời gian từ tháng 11/2016 - 12/2022. Kết quả: Góc Böhler trước mổ có độ lớn trung bình là -1,9º (-40º ÷ 22º). Phân loại theo Sander: Gãy loại IIA, IIB, IIC có lần lượt 3 BN, 4 BN, 10 BN. Gãy loại IIIAB, IIIAC, IIIBC có lần lượt là 1 BN, 4BN, 6 BN; gãy loại IV có 8 BN. Góc Bӧhler sau mổ đạt 31,5º ± 6,4º, góc Gissane đạt từ 115º - 1400. 52/56 BN có vết mổ liền kỳ đầu, 2 BN có vết mổ liền sẹo thì 2, và 2 BN không liền vết mổ. Tổn thương thần kinh hiển gặp ở 9 BN. 36/56 BN không có biểu hiện viêm khớp sên gót, tuy nhiên có tới 20 BN có biểu hiện thoái hóa khớp sên gót ở độ I và II và không có liên quan đến kiểu gãy xương gót. Điểm AOFAS Ankle-Hindfoot đạt 79,5 ± 8,6 điểm. Kết luận: Phẫu thuật kết xương gót phạm khớp bằng nẹp khóa cho kết quả tốt.
THE ALL-INSIDE ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION WITH FIBER-LOOP AUGMENTATION
Authors: Vu Anh Dung , Tran Quang Dung , Pham Ngoc Thang
Published: December 2023

Objectives: To evaluate the functional outcomes in patients who underwent anterior cruciate ligament (ACL) reconstruction with fiber-loop augmented to reinforce the ligament, acting as a secondary stabilizer. Methods: A retrospective study was conducted on 25 patients who underwent the all-inside ACL reconstruction with the addition of fiber-loop inside the ACL graft in the Department of Joint Surgery, Military Hospital 103, from August 2022 to August 2023. Patients were evaluated pre-operatively and finally post-operatively via the Lachman test, Pivot shift test, and Lysholm score. Results: The mean follow-up was 9.84 months; the mean age was 33.04 ± 9.95 years. 24 patients (96%) were post-operatively Lachman negative. The pivot-shift test showed 96% of patients absent or glide after surgery. The Lysholm knee score at the last visit was good and very good in 96% of the patients; the mean score was 92.56 ± 4,53. Conclusion: This study showed good functional outcomes of arthroscopic ACL reconstruction with fiber-loop augmentation to reinforce the ligamental graft. There is a need for more comparative studies with longer follow-ups and large sample sizes.
ANALISIS PENGARUH POSTER ERGONOMI KERJA TERHADAP MANAJEMEN KINERJA PEGAWAI LONDRI CUCI KILOAN
Authors: Ramawisari Ica , Bahri Nurul Fitriana , Chalik Chris
Published: December 2023

Ergonomi adalah ilmu yang mempelajari sifat, kemampuan dan juga keterbatasan manusia untuk merancang suatu sistem kerja sehingga orang dapat hidup dan juga bekerja pada suatu sistem dengan baik dan mencapai tujuan yang diinginkan secara efektif, aman dan nyaman. Ergonomi kerja adalah aspek penting dalam lingkungan kerja yang dapat memengaruhi kenyamanan, produktivitas, dan kesejahteraan pegawai. Penelitian ini bertujuan untuk menganalisis dampak penggunaan poster ergonomi kerja pada manajemen kinerja pegawai di industri Londri Cuci Kiloan. Penelitian ini menggunakan metode kualitatif untuk menganalisis pengaruh poster ergonomi kerja terhadap manajemen kinerja pegawai di industri Londri Cuci Kiloan melalui pendekatan studi kasus yang memungkinkan peneliti untuk memahami secara mendalam persepsi, sikap, dan pengalaman subjektif pegawai terkait dengan penggunaan poster ergonomi. Data dikumpulkan melalui wawancara mendalam dengan sejumlah pegawai di tempat yang telah dipasangi poster ergonomi, serta melalui observasi langsung dalam lingkungan kerja. Analisis data kualitatif dilakukan dengan menggunakan teknik pemilahan, pengelompokan, dan interpretasi temuan-temuan kualitatif, sehingga hasil penelitian ini akan memberikan pemahaman yang lebih komprehensif tentang bagaimana poster ergonomi kerja memengaruhi persepsi, perilaku, dan manajemen kinerja pegawai Londri Cuci Kiloan dari perspektif yang lebih mendalam dan kontekstual. Hasil penelitian ini menunjukkan bahwa pemasangan poster ergonomi kerja dapat memiliki dampak positif pada manajemen kinerja pegawai di industri Londri Cuci Kiloan.  Poster ergonomi tidak hanya meningkatkan pemahaman pegawai tentang ergonomi kerja tetapi juga berkontribusi pada peningkatan produktivitas dan kepuasan pegawai secara keseluruhan. Oleh karena itu, disarankan agar perusahaan-perusahaan dalam industri ini mempertimbangkan pemasangan poster ergonomi sebagai salah satu upaya untuk meningkatkan manajemen kinerja pegawai mereka.
Սուրբ Ներսէս Շնորհալու «Հաւատով խոստովանիմ» աղօթքի լեզուաոճական առանձնայատկութիւնները
Authors: Առաքելեան Կարինէ
Published: December 2023

Saint Nerses Shnorhali is one of the brightest representatives of Armenian spiritual, scientific, literary and musical intellect. His merit in the literary field is too great: he was a highly multi-genre creator, left a legacy to his people poems, verses, riddles, songs, epistles, prayers, etc.. The most famous and especially popular among prayers is "I confess whith faith", which is part of the church service. It consists of twenty-four strophes and corresponds to the twenty-four hours of the day. The deep, multi-layered, rich content is combined with the accessible yet opulent and beautiful language of prayer, with the skillful and appropriate use of various ns of imagery, creating a perfect harmony of form and content.

Одним из самых ярких представителей армянской духовной, научной, литературной и музыкальной мысли является Святой Нерсес Шнорали. Велики его заслуги на литературном поприще: он был в высшей степени многожанровым творцом, оставил своему народу наследие в виде поэм, стихов, кладами, песен, загадок, посланий, молитв и т.д.. Наиболее известным и особенно популярным среди молитв является «Сь вьрою исповьдую», являющаяся частью церковного богослужения. Она состоит из двадцати четырех строф и соответствует двадцати четырем часам суток. Глубокое, многослойное, богатое содержание сочетается с доступным, но богатым и красивым языком молитвы, с умелым и уместным использованием различных средств изображения, создавая совершенную гармонию формы и содержания.
Քրիստոնեական ընկալումներն արցախյան բանահյուսության մեջ․ հեքիաթներ
Authors: ՍԱՐԳՍՅԱՆ Տ. ԱԹԱՆԱՍ ԱԲԵՂԱ
Published: December 2023

Общеизвестно, что сказки являются одним из наиболее важных и богатых материалом жанров фольклора. В рамках представленной статьи мы изучили и объединили сказки, встречающиеся в фольклоре Арцаха, в которых присутствуют христианские представления, образы и эпизоды с чисто религиозными мотивами. Таким образом, мы рассмотрели и провели сравнительный анализ сказок, а также изучили их генеалогию и семантику. Следует отметить, что в Арцахе не мало таких сказок с ярко выраженными христианскими и назидательными мотивами. В данной статьи мы также стремились выяснить, какую роль играет христианское мировоззрение в сказках, вошедших в арцахский фольклор, и насколько они идентифицируются со сказками, распространенными в других армянских регионах. Дело в том, что нравственные посылы, содержащиеся ской Армении.
It is known that the fairy tales are one of the most important and widespread sections of folklore. Within the framework of the presented article, we have studied and combined the fairy tales found in the folklore of Artsakh, in which there are Christian perceptions, episodes with religious motifs. Thus, we have examined them and made a comparative analysis, as well as studied their genealogy and significance. It is worth noting that the number of such tales is about a dozen. Within the framework of this article, we aimed to find out what role Christian perceptions have in the tales that are part of Artsakh folklore and to what extent they identify with the tales born in other Armenian settlements. The presence of religious motifs in Artsakh fairy tales and folklore in general gives an opportunity to conclude that the people of Artsakh lived and lives with a Christian value system and worldview, as the fairy tales are created on the basis of various manifestations of folk life.
Կրթութիւն, իրաւունք, լեզու. միջնադարից լուսաւորութիւն
Authors: Պողոսյան Սամվել սարկավագ
Published: December 2023

Среди армянской общины Османской империи, начиная с 18 века, европейское просвещение распространялось по многим векторам, что привело к значительным изменениям образования, литературного языка и юридического статуса. Осуществленные изменения, в течении последующих десятилетий, оказывали существенное влияние на общее мировоззрение армянского народа. В какой-то мере это был не только процесс секуляризации и попыток приноравливания к условиям данного времени, но также культурного пробуждения и подъема.
Among the Armenian community of the Ottoman Empire, the European Enlightenment spread by many vectors and led to significant changes from the 18th century onwards. Under these influences, medieval modes of education, legal status, and literary language underwent an unprecedented transformation. These changes had a decisive influence not only on the Church in the following decades, but also on the general outlook of the Armenian people. It was in some measure a process of secularization, but also of revival and attempt to adapt to the conditions of the time.
On the solution of T−controllable abstract fractional differential equations with impulsive effects
Authors: Ram Gautam Ganga , Pinelas Sandra , Kumar Manoj , Arya Namrata , Bishnoi Jaimala
Published: December 2023

In this research article, we delimitate the definition of mild solution for abstract fractional differential equations with state-dependent delay (AFDEw/SDD) of order α ∈(1,2) with impulsive effects and compare the solution to the second-order impulsive differential equations. Further, we obtain sufficient conditions of the existence of mild solution for instantaneous and non-instantaneous impulsive fractional functional differential inclusions with state-dependent delay (IFDIw/SDD) using the multi-valued fixed point theory and operator techniques. Furthermore, we study the trajectory controllability (T−controllability) of the AFDEw/SDD. At last, we present some examples to illustrate the sufficient conditions involving partial and ordinary derivatives.
«HALAL». WHAT DO WE KNOW ABOUT THIS FROM THE POSITION OF DIETOLOGY AND MEDICINE
Authors: Завьялова А.Н. , Игнатова П.Д. , Новикова В.П. , Хранилова Д.А.
Published: December 2023

Религиозные течения влияют на выбор рационов, продуктов и блюд, а также времени приема пищи. В многоконфессиональных странах предприятия пищевой промышленности с целью привлечения массового потребителя выпускают продукцию, разрешенную институтом религии той конфессии, к которой принадлежит потребитель. В ряде религий диетические предписания особо строгие как в повседневной жизни, так и в период религиозных постов. «Халяль» — структура разрешенных действий, пищи, производства. В плане питания в религии ислам особо строгие правила: запрещены в пищу мертвечина, свинина, мясо задушенных животных, этанол, искусственные красители и ингредиенты, пивные дрожжи, желатин (ввиду его возможного происхождения из свинины), растительные и прочие одурманивающие вещества. При упоминании слова «халяль» большинство из нас предполагает особое мясо и исключение свинины. Однако к «халяль» можно отнести и молочные продукты, и кондитерские изделия, и лекарственные препараты. Для религиозного мусульманина важно соблюдение законов. В статье отмечены ключевые моменты в выборе не только продуктов питания «халяль», детского питания, но и лекарственных средств категории «халяль».

Religious currents also influence the choice of diets, foods and dishes, as well as the time of eating. In multi-confessional countries, food industry enterprises, in order to attract the mass consumer, produce products that are permitted by the institute of religion of the confession to which the consumer belongs. In a number of religions, dietary prescriptions are especially strict both in everyday life and during religious fasts. Halal is a permitted structure of actions, food, production. In terms of nutrition in the religion of Islam, there are especially strict rules: carrion, pork, meat of strangled animals, ethanol, artificial colors and ingredients, brewer’s yeast, gelatin (in view of its possible origin from pork), vegetable and other intoxicating substances are prohibited. At the mention of the word Halal, most of us assume special meat, and the exclusion of pork. However, dairy products, confectionery and medicines can also be classified as halal. For a religious Muslim, the observance of laws is important. The article highlights the key points in the choice of not only Halal food, baby food, but also Halal medicines.
NEW CORONAVIRUS INFECTION. HISTORY OF CORONAVIRUS FROM ORIGIN TO EPIDEMIOLOGY
Authors: Ниязов Р.М. , Савченко И.В. , Веретенникова Е.И. , Магомедова А.М.
Published: December 2023

Впервые РНК вируса SARS-CoV-2 была выявлена 8 декабря 2019 года у пациента с пневмонией. 31 декабря 2019 года Всемирная организация здравоохранения (ВОЗ) была оповещена о нескольких случаях вирусной пневмонии, вызванной неизвестным патогеном. 7 января 2020 года информация о новом вирусе была подтверждена, а сам вирус был отнесен к коронавирусам. В январе 2020 года ВОЗ объявила вспышку, связанную с SARS-CoV-2, а 11 марта 2020 года охарактеризовала принявшее мировой масштаб распространение болезни как пандемию. В данном обзоре затронута история открытия коронавирусов в целом, а также строение вируса SARS-CoV-2.

For the first time, SARS-CoV-2 virus RNA was detected on December 08, 2019 in a patient with pneumonia. On December 31, 2019, the World Health Organization (WHO) was notified of several cases of viral pneumonia caused by an unknown pathogen. On January 7, 2020, information about the new virus was confirmed, and the virus itself was classified as a coronavirus. In January 2020, WHO declared an outbreak associated with SARS-CoV-2, and on March 11, 2020, characterized the worldwide spread of the disease as a pandemic. This review touches upon the history of the discovery of coronaviruses, as well as the structure of the SARS-CoV-2 virus.
RENDIMIENTO INTELECTUAL Y DESEMPEÑO EJECUTIVO EN ADULTOS CON ALTAS CAPACIDADES DE LIMA METROPOLITANA
Authors: Pereyra R. Andrés
Published: December 2023

Este estudio describe la relación entre medidas de rendimiento intelectual (Gc y Gf) y desempeño ejecutivo (FE. Los datos se obtuvieron de muestra conformada por 13 participantes altamente inteligentes y miembros activos de MENSA – Perú, para su evaluación se usó el K-BIT y BANFE-2 respectivamente. Tras el análisis descriptivo de los principales estadísticos, utilizando el coeficiente de correlación r de Spearman, se encontró una correlación moderada y significativa entre la inteligencia no verbal (Gf), la memoria de trabajo y las funciones ejecutivas (.6608, p < 0.02); entre la inteligencia no verbal y las funciones básicas (control inhibitorio, seguimiento de instrucciones y estimación de riesgo), hubo una correlación moderada (.545, p < 0.05). Asimismo, no se hallaron evidencias de relación entre inteligencia verbal con memoria operativa y funciones ejecutivas (.382, p <.2). Se concluye que se debe tomar en cuenta el rol y su evaluación de las funciones ejecutivas como capacidades cognitivas que distinguen a la población de altas capacidades intelectuales.
PROPIEDADES PSICOMÉTRICAS DE LA ESCALA DEL TRASTORNO DE ANSIEDAD GENERALIZADA: GAD-7 EN UNIVERSITARIOS DE LIMA, PERÚ
Authors: Anicama G. José , Ignacio C. Felipe , Talla B. Karina , Bruno C. Brunela
Published: December 2023

La ansiedad generalizada en estudiantes universitarios merece mayor atención debido al incremento de la prevalencia y a la gran comorbilidad con otros trastornos de ansiedad, por lo cual es necesario contar con instrumentos válidos y fiables. El objetivo fue evaluar las propiedades psicométricas del GAD-7 en universitarios de Lima, Perú. Se realizó un estudio psicométrico instrumental, transversal, descriptivo correlacional, en 300 universitarios de Lima, de uno u otro sexo, entre 18 y 50 años, quienes completaron la Escala GAD-7 en clases virtuales. Los resultados muestran que los coeficientes de correlación ítem-test corregida van de .853 a .875. El análisis factorial permitió confirmar que existe una sola dimensión, además, el alfa de Cronbach fue .87 y el omega de McDonald’s .88. La ansiedad severa fue 22.6%.
FUNCIONAMIENTO FAMILIAR E IDEACIÓN SUICIDA EN ESTUDIANTES DE TRES INSTITUCIONES EDUCATIVAS ESTATALES DE VILLA EL SALVADOR
Authors: Huamani M. Stefany
Published: December 2023

Se determinó la relación entre el funcionamiento familiar e ideación suicida en educandos de secundaria de tres instituciones educativas estatales de Villa El Salvador. Con una muestra conformada por 438 estudiantes que oscilan entre las edades de 12 a 17 años de ambos sexos. Los instrumentos empleados fueron la Escala Apgar Familiar adaptado por Castilla, Caycho, Shimabukuro y Valdivia (2014) y la Escala de ideación suicida (SS-I) de Beck, Kovacs y Weissman adaptado por Eugenio y Zelada (2011) para medir ambas variables. Los hallazgos demostraron que predomina el nivel leve de disfunción familiar (34.0%), en cuanto a la ideación suicida, predomina el nivel medio (40,6%). Se identificó una relación significativa entre el funcionamiento familiar e ideación suicida (p=.000), así como, entre los niveles de funcionamiento familiar con cada una de las dimensiones de ideación suicida. Se concluye que a mayor funcionamiento familiar habrá menor ideación suicida.
ESTEREOTIPOS DE ROLES DE GÉNERO Y AGRESIVIDAD EN TRABAJADORES DE LA MUNICIPALIDAD DE ALTO LARAN - 2022
Authors: Ramírez S. Lesly , Contreras C. Karol
Published: December 2023

El estudio buscó como objetivo fue establecer como los estereotipos de roles de género se relacionan con la agresividad en los colaboradores de la Municipalidad de Alto Laran en 2022. Se seleccionó como no experimental transversal al diseño, siguiéndose los lineamientos de un enfoque cuantitativo bajo un alcance correlacional. Se partió de una muestra de 108 colaboradores de edades entre 18 a 70 años. Se utilizaron los instrumentos del Inventario de Agresividad de Buss & Perry adaptado por Matalanares (2012) y Estereotipos de Roles de Género de Bem adaptado por Razul (1991), ambos en versión peruana. Los resultados revelaron que el 53.7% de los colaboradores mostraron una mayor predominancia en la dimensión de distracción o filtros, y el 47.2% presentó niveles medio significativos de agresividad. Demostrándose que, no existe relación entre ambas variables.
FACTORES ASOCIADOS A LA VIOLENCIA EN EL NOVIAZGO, UNA REVISIÓN SISTEMÁTICA ENTRE LOS AÑOS 2019 – 2023
Authors: Caller L. Juan , Arrasco S. Fiorella
Published: December 2023

El propósito de este estudio fue realizar una revisión sistemática entre 2019 y 2023 para identificar factores asociados a la violencia en el noviazgo y su medición. Para lo cual se han revisado los artículos que han sido publicados entre el 2019 y 2023 en español e inglés en las siguientes bases: Redalyc, Scielo, Dialnet, Ebsco y Google académico, que estén dentro del Cuartil 1 (Q1), cuartil 2 (Q2), cuartil 3 (Q3) y cuartil 4 (Q4). La búsqueda inicial arrojó un total de 6095 artículos, los cuales finalmente fueron sistematizados, de los cuales 20 cumplieron con los criterios de inclusión y exclusión. Los hallazgos mostraron diferencias en el desarrollo madurativo de adolescentes y adultos e identificaron siete factores independientes que contribuyen a la prevalencia de la violencia en el noviazgo. En resumen, la revisión nos permite arrojar nueva luz sobre las cuestiones planteadas, aún se necesita profundizar más en esta problemática a nivel local.
EVIDENCIAS PSICOMÉTRICAS DE LA ESCALA BÁSICA DE EMPATÍA EN ADOLESCENTES DE UN DISTRITO DE LIMA SUR
Authors: Chauca C. Max , Molfino V. Alessandra
Published: December 2023

La empatía hoy en día es considerada esencial para el bienestar mental y físico del individuo en cualquier etapa de su vida, permitiendo relaciones sociales y laborales saludables y que son necesarios medir a través de instrumentos válidos y confiables El presente estudio tuvo como objetivo fin determinar las evidencias de confiabilidad y validez de la escala básica de empatía para adolescentes en una muestra de 219 estudiantes secundarios de un distrito del cono sur de Lima. La metodología incluye además un diseño no experimental, trasversal y tipo psicométrico e instrumental. Los resultados confirmaron que la variable contenía 2 factores subyacentes que explicaba el 48.60% de la varianza mediante el análisis factorial exploratorio. Resultados que se confirmaron mostrando un modelo de estructura aceptable, formada por 11 ítems, con índices: CFI=.93, TLI=.92 y NFI.91. La consistencia interna para la escala total obtuvo un valor de Alfa .92, mientras que para la dimensión afectiva fue de .88 y para la dimensión cognitiva de .85. Por último, se obtuvo la confiabilidad por mitades, donde se demostró correlaciones positivas con coeficientes superiores a .89.
CLIMA ORGANIZACIONAL Y EL DESEMPEÑO LABORAL DEL PERSONAL DE SEGURIDAD DE UN HOSPITAL GENERAL DE LIMA METROPOLITANA, 2022
Authors: Mujica M. Elmer
Published: December 2023

El objetivo fue analizar la relación existe entre el clima organizacional y el desempeño laboral de los trabajadores de seguridad de una institución hospitalaria en Lima, 2022. Se ejecutó una investigación de tipo descriptiva-correlacional y de diseño no experimental. La muestra estuvo conformada por 96 personas entre los 20 a 55 años. Los instrumentos empleados fueron el Cuestionario de Percepción del Desempeño Laboral y Cuestionario del Clima Organizacional. Los resultados indican que, el clima organizacional sí presenta correspondencia con el desempeño laboral de los colaboradores de una institución hospitalaria en Lima, 2022, con un Rho = 0,843 que representa una correspondencia fuerte, asimismo, es significante con una p = 0,01.
FACTORES PSICOSOCIALES Y SATISFACCIÓN LABORAL EN TECNÓLOGOS MÉDICOS DE LA REGIÓN 1
Authors: Garcia T. Neida
Published: December 2023

La presente investigación tuvo como objetivo determinar la relación entre Factores Psicosociales y Satisfacción Laboral en los tecnólogos médicos que laboran en la región 1. El diseño es no experimental y transversal ya que investiga fenómenos en su contexto natural sin cambiar o manipular las variables, el tipo fue correlacional con los fines de identificar el tipo de relación existente entre las variables del presente estudio. La muestra fue de 250 tecnólogos médicos de ambos sexos. Los instrumentos fueron el Cuestionario Batería "UNIPSICO", para factores psicosociales y la Escala de satisfacción laboral. Los resultados arrojaron que existe relación directa, nivel bajo y altamente significativa (Rho=.278; p<0.00) entre factores psicosociales y satisfacción laboral, comprendiendo que a mayor presencia de los factores mayor será la satisfacción laboral en el personal de los tecnólogos médicos que laboran en la Región Lima, 2022.
Ferramenta de apoio à decisão no rastreamento mamográfico para mulheres de 40 a 49 anos
Authors: Santos Renata Oliveira Maciel dos , Assis Monica de , Migowski Arn
Published: December 2023

Introdução: O rastreamento do câncer de mama no Brasil é recomendado para as mulheres de 50 a 69 anos, conforme diretrizes nacionais para a detecção precoce do câncer de mama do Instituto Nacional de Câncer/Ministério da Saúde. Embora ele seja tradicionalmente difundido como prática apenas benéfica, as evidências científicas apontam sua complexidade e a necessidade de comunicar o balanço entre os riscos e os benefícios, sobretudo em mulheres mais jovens. Objetivo: Descrever o processo participativo de elaboração de uma ferramenta de apoio à decisão para o rastreamento do câncer de mama quando buscado por mulheres com idade entre 40 e 49 anos no Brasil. Métodos: Estudo qualitativo-participativo que envolveu nove médicos de diferentes estados do Brasil e 104 mulheres na etapa de elaboração e 40 na de avaliação da ferramenta, seguindo as recomendações do International Patient Decision Aid Standards, em quatro etapas: rodas de conversa, síntese de evidências, revisão de ferramentas e avaliação da ferramenta por médicos e mulheres. Resultados: A ferramenta elaborada é inédita no Brasil e todos os médicos que a utilizaram a consideraram útil na conversa sobre os riscos e benefícios do rastreamento; 88,9% avaliaram que as informações facilitaram o entendimento — visão compartilhada por 80% das mulheres — e 77,8% consideraram que reduziu ou não interferiu no tempo de consulta. A ferramenta foi posteriormente aprimorada conforme as críticas e sugestões. Conclusões: O estudo mostrou o alcance do objetivo da ferramenta em oferecer suporte à decisão compartilhada e boa aceitação entre médicos e mulheres.
Effet antioxydant et capacité quenching de l’oxygène singulet du beurre de karité et de sa fraction phénolique
Authors: Goumbri Bertrand W. F. , Jansen Olivia , Marini Roland D. , Frederich Michel , Semdé Rasmané , Somé Touridomon Issa , Danthine Sabine , Mouithys-Mickalad Ange
Published: December 2023

Introduction : Les rayons ultraviolet (UVR) peuvent-être nocifs pour la peau, par l’action des radicaux libres générés par les espèces réactives de l’oxygène (ROS), comme l’oxygène singulet (1O2). Le beurre de karité (BK) revendique des propriétés de photoprotection contre les rayons UVA et UVB, par l’action de ses insaponifiables. Notre étude consiste à déterminer la capacité antioxydante du BK extrait au Burkina Faso, et à évaluer in vitro son pouvoir de photoprotection indirecte.

Matériel et Méthodes : Les composés phénoliques totaux du BK brut, ont été obtenus par extraction liquide-liquide et dosés par technique colorimétrique avec le réactif de Folin-Ciocalteu. Leur capacité antioxydante a été évaluée par les tests colorimétriques ABTS et DPPH. Un modèle expérimental UVR- like a été mis au point afin d’évaluer in vitro le pouvoir photo-protecteur indirecte du beurre brut et de ses extraits phénoliques par photosensibilisation du Rose Bengal (RB) en présence de l’anthracène.

Résultats : La teneur en phénols totaux des échantillons de BK du Burkina Faso était comprise entre 14,16 ± 2,33 et 82,99 ± 8,70 ppm d'équivalent pyrogallol. Ces composés phénoliques ont montré une activité antiradicalaire dose-dépendante. Sur modèle acellulaire expérimental UVR-like, le beurre brut et sa fraction phénolique ont montré une capacité quenching dose-dépendante de l’1O2 par photosensibilisation du RB, en présence d’anthracène, ce qui met en évidence une photoprotection indirecte du beurre brut et de ses composés phénoliques.

Conclusion : Le BK brut peut être utilisé pour ses propriétés antioxydantes dû à sa fraction phénolique. Outre ses propriétés antioxydantes, le BK a un pouvoir de photoprotection indirecte, par effet quenching de l’O2, qui est plus prononcé que celui de sa fraction phénolique. L'effet photoprotecteur sur modèle UVR-like pourrait donc être attribuable à un effet antioxydant indirecte, et à l’action des insaponifiables.
Emulsions de Pickering stabilisées par des Nanoparticules Solides Lipidiques : Taux de couverture et comportement interfacial
Authors: Dieng Sidy Mouhamed , Fall Ahmedou Bamba Kouemel , Anton Nicolas , Bouriat Patrick , Thioune Oumar , Sy Papa Mady , Massaddeq Nadia , Diop Moussa , Diarra Mounibé , Vandamme Thierry
Published: December 2023

Introduction : Ces dernières années, le développement de biomatériaux à faible impact environnemental a attiré un intérêt croissant. Dans ce contexte, les nanoparticules lipidiques ont émergé comme une solution privilégiée dans la recherche et l'industrie. L'objectif de cette étude était de mettre au point des émulsions Pickering O/W stabilisées exclusivement par des nanoparticules lipidiques solides (SLNs). Ces émulsions de Pickering sont une nouvelle génération de transporteurs lipidiques, à la fois sûrs, non toxiques, biocompatibles et sensibles à la température.

Matériel et Méthodes : La première partie de l'étude se concentre sur la compréhension du comportement interfacial des SLNs et les mécanismes de stabilisation associés aux nanoémulsions formulées par ultrasons. Les recherches ont exploré la couverture de surface en fonction des fractions volumiques des phases dispersées et de la taille des SLNs. La deuxième partie de l'étude aborde l'adsorption des SLNs à une interface modèle entre l'huile et l'eau, en évaluant la tension superficielle et la rhéologie. Cela a été réalisé au moyen d'une analyse de la forme d'une goutte axi-symétrique (à l'aide d'un tensiomètre de goutte), en suivant l'évolution de la tension interfaciale et du comportement rhéologique.

Résultats : Ces expériences ont démontré de manière concluante que la stabilisation des nanogouttelettes est effectivement assurée par les nanoparticules, tout en mettant en lumière les limites de cette formulation. La caractérisation des dimensions et de la morphologie des émulsions a permis de confirmer nos hypothèses. Par ailleurs, nous avons procédé à la caractérisation du phénomène régissant les interactions entre les nanogouttelettes et l'interface, tout en décrivant le comportement rhéologique de la monocouche de SLNs à l'interface.

Conclusion : En conclusion, les émulsions de Pickering stabilisées par les SLNs se révèlent être des nano-transporteurs de médicaments innovants et très efficaces. Elles ouvrent ainsi de nouvelles perspectives en tant que système de délivrance de médicaments sensible à la température.
Nanogels obtenus par interactions électrostatiques ; Formulation, caractérisations et études de libérations
Authors: Dieng Sidy Mouhamed , Fall Ahmédou Bamba Koueimel , Sy Papa Mady , Djiboune Alphone Rodrigue , Niass Mamadou , Diop Moussa , Diouf Louis Augustin Diagua , Mbaye Gora , Thioune Oumar , Diarra Mounibé
Published: December 2023

Introduction : Le domaine de la nanoformulation connaît un essor continu depuis l'avènement de vecteurs permettant d'encapsuler des molécules à la fois hydrosolubles, liposolubles et amphiphiles pour la délivrance de médicaments. Avec l'émergence prédominante de nouveaux agents thérapeutiques principalement lipophiles, le développement de nouvelles formulations capables de les transporter efficacement vers leurs cibles représente aujourd'hui un défi essentiel. L'objectif de notre étude est de formuler des nanogels à base de polymères et de lipides en exploitant les interactions électrostatiques en surface.

Matériel et Méthodes : Nous avons élaboré des nanogels mixtes en combinant un polymère lipophile, le poly (anhydride maléique-alt-1-octadécène) (PMAO), qui se solubilise dans la phase huileuse, avec un polymère hydrophile, le chitosane, qui se solubilise dans la phase aqueuse.

La méthode de formulation repose sur l'instauration d'interactions électrostatiques entre un polymère à charge positive dans la phase aqueuse et les groupements carboxylates présents à la surface des nanogouttelettes formant ainsi les nanogels.

La caractérisation a été réalisée à l'aide de techniques telles que la diffusion dynamique de la lumière, la zétamétrie et la spectrophotométrie UV-Visible.

Résultats : Sur l’ensemble des préparations retenues aucun phénomène d’instabilité n’a été observé. Concernant la taille et l’indice de polydispersité des nanogels, nous avons trouvé qu’ils dépendent du pourcentage de Chitosane. Le potentiel zêta évolue en fonction de la quantité de Chitosane. La libération du Kétoproféne est comparable à celle des molécules lipophiles). En effet, nous n’avons observé que 6% de libération après 210 min.

Conclusion : Notre étude à montrer la possibilité d’élaborer des nanogels mixtes constitué de lipide et de polymère en vue du transport et de la libération de PA lipophiles.
Développement d’un procédé de production et de stérilisation de liposomes en une seule étape en utilisant le dioxyde de carbone supercritique
Authors: Delma Kouka Luc , Penoy Noémie , Sakira Abdoul Karim , Egrek Sabrina , Sacheli Rosalie , Grignard Bruno , Hayette Marie-Pierre , Somé Touridomon Issa , Evrard Brigitte , Piel Géraldine , Semdé Rasmané
Published: December 2023

Introduction : les liposomes sont des vecteurs ciblés de médicaments présentant aujourd’hui un grand intérêt pharmaceutique et thérapeutique et généralement administrés par voie parentérale. Cependant, leur fabrication industrielle ainsi que leur stérilisation demeurent un défi. Le dioxyde de carbone supercritique (CO2Sc) constitue aujourd’hui une méthode alternative de production des liposomes et présente également des propriétés stérilisantes. Le but de ce travail est de développer un procédé innovant de production et de stérilisation des liposomes en une seule étape en utilisant le ScCO2.

Méthodologie : la capacité de 4 conditions ScCO2 à atteindre le niveau d’assurance de stérilité (SAL) de 10-6 exigé pour des liposomes a d’abord été évaluée en utilisant les spores de Bacillus Atropheus comme indicateur microbiologique de référence, en vue de sélectionner des conditions opératoires de procédé : C1 (70° C/150 bar/240 min), C1A (80° C/240 bar/30 min), C1B (80° C/150 bar/60 min), C1C (80° C/240 bar/60 min). Les conditions sélectionnées ont ensuite été utilisées pour la production de deux formulations de liposomes : F1 (HEPC/DC-CHOL/CHOL/DSPE-PEG2000 50,05/29,40/0,60/19,95 % m/m) et F2 (HSPC/CHOL/DSPE-PEG2000 65/30/5 % m/m). Les liposomes obtenus ont enfin fait l’objet d’une caractérisation physicochimique et microbiologique.

 

Résultats : les résultats ont montré l’atteinte du SAL requis pour les liposomes avec les conditions C1, C1B et C1C, lesquelles ont été utilisées pour les essais de production/stérilisation des deux formulations. Concernant les liposomes résultants, les résultats ont montré l’atteinte du SAL requis avec les 2 formulations pour toutes les 3 conditions. Par ailleurs des liposomes de caractéristiques appropriées pour une administration parentérale (taille <200 nm, PdI ≤ 0,3) ont été obtenus avec la formulation F2 pour toutes les 3 conditions.

Conclusion : Le ScCO2 pourrait être utilisé pour la production et la stérilisation de liposomes dans un procédé en une seule étape.
Formulation of shea butter-based lipid nanoparticles for topical and transdermal applications
Authors: YAMEOGO B. Gérard Josias , KABORE Carmen F. W. , SOMBIE B. Charles , ZIME DIAWARA Hermine , WOUESSIDJEWE Denis , SEMDE Rasmané , GEZE Annabelle
Published: December 2023

Introduction: Shea butter is a natural lipid widely used in topical formulations because of its hydrating, anti-inflammatory and regenerative properties on the skin. The aims of this study was to develop lipid- based nanoparticles using local shea butter as building material for topical and transdermal applications. Methods: The nanoparticles of shea butter were made using three different processes (high shear homogenization, phase inversion temperature or solvent injection techniques. The formulation factors were optimized. The obtained nanoparticle suspensions were evaluated for particle size using dynamic light scattering, polydispersity index, zeta potential and physicochemical stability. Subsequently the aqueous colloidal suspension obtained by high shear homogenization technique was converted into a gel by adding 0,5 % Carbopol 980NF (polymer) as a gelling agent and subsequent neutralization with sodium hydroxide. The gel formulations were investigated for pH and viscosity measurements at day

The viscosity was assessed at 26°C using a rotational viscometer STS-2011 (shear rate of 2 s-1, spindle n°R4, 10 rpm).

Results: The optimized conditions make it possible to obtain nanoparticles with average sizes of 54.1 ±

5.0 nm, 99.1 ± 1.0 nm and 161.5 ± 4.4 nm, when the phase inversion temperature, high shear homogenization or the solvent injection techniques were respectively used. All optimized formulations

 

showed a narrow size distribution and the zeta potential values were between -20 and -38 mV depending on the technique used. The three colloidal suspensions were considered physically stable at room temperature for at least three months as no significant changes in mean size, polydispersity index or zeta potential values were observed. The gel formulations exhibited viscosities of 32 800 ±100 mPa.s with pH values of 5,0 ± 0,5.

Conclusion: In order to evaluate their potential as a new carrier system for skin delivery and as a follow- up to these promising initial results, morphological analysis of the nanosystems and evaluation of their encapsulation capacity are in progress, before in vitro skin permeation and retention studies are considered.