bluuebunny/crossref_metadata_2025 huggingface dataset:
Implementation of the book tuhfatul athfal in maintaining the quality of qur'an recitation among students of Pondok Pesantren Tahfidzul Qur'an Bilal Bin Rabah Sukoharjo, Central Java
Authors: Al Adni Muhammad Wijdan Aly , Nurhidayati Indah , Khoirunnisa Izzun , Al Hawary Abdu Robbi Rasul Nuh
Published: January 2025

The implementation of the Tuhfatul Athfal book in Tajweed education at Pondok Pesantren Tahfidzul Qur'an Bilal bin Rabah Sukoharjo is the focus of this study, given the importance of maintaining the quality of Quranic recitation. This study aims to analyze the implementation of this book, identify the factors affecting its success, and develop strategies to address gaps in Tajweed understanding and application among students. The research employs a qualitative descriptive method, with data collected through in-depth interviews, participatory observations, and documentation. The findings indicate that the Tuhfatul Athfal book is effectively implemented through interactive and practice-based teaching methods. However, challenges such as differences in students' levels of understanding, limited time for guidance, and students' motivation were identified. To address these gaps, it is recommended to adjust teaching methods, provide additional guidance time, use technology as a supplementary tool, and strengthen motivation and support from instructors. By applying these strategies, it is hoped that the quality of Quranic recitation among students will improve and the gaps in Tajweed understanding will be minimized.
The effect of using game-based learning (bamboozle) on the learning motivation of fourth grade students at Madrasah Ibtidaiyah Payungan, Kaliwungu District, Semarang Regency
Authors: Rahayu Erni Tri , Amin Lailla Hidayatul , Gunawan Herri , Hawary Abdu Robbi Rasul Nuh Al
Published: January 2025

The transformation of education in Indonesia requires the world of education to be able to adapt to changing times, which is the widespread use of various kinds of digital technology in the world of education. Digital technology has become an important part of today's learning methods. The lack of teacher understanding of the use of renewable learning media methods and media causes low student motivation. The purpose of this study is the first to describe how the use of Game-Based Learning (Baamboozle) in the IPAS subject of grade IV students of Madrasah Ibtidaiyah Payungan in the 2024/2025 academic year, the second to describe how high is the learning motivation of grade IV students of Madrasah Ibtidaiyah Payungan in the IPAS subject, the third to describe how big is influence of the use of Game-Based Learning (Baamboozle) on the students’ learning motivation of IV grade students of Madrasah Ibtidaiyah Payungan in the IPAS subject in the 2024/2025 academic year. This research method uses a quantitative approach. The population in this study was the IV grade students of Madrasah Ibtidaiyah Payungan, Kaliwungu Semarang with a total of 39 students. The research was conducted at Madrasah Ibtidaiyah Payungan with sampling using comlete sampling totaling 39 students. While the data collection is done through observation, questionnaires and documentation where the instrument of the questionnaire has been validated and reliable. Furthermore, it was analyzed by unit analysis and prerequisite tests and ends with hypothesis testing using product moment and simple linear regression tests. The results of this study were 1) The level of the used of Game-Based learning (Baamboozel) in IV grade students of Madrasah Ibtidaiyah Payungan was very high, seen in the classification of its value showes 38 students were in the category of very high value category. 2) The level of students’ learning motivation of IV grade students of Madrasah Ibtidaiyah Payungan showed the highest value of 80 and the lowest value was 72, while the mean was 77,15 with a standard deviation of 2,37. It was known that the value of student learning motivation in IPAS lessons was 20 students got quite high scores. 3) on the product moment test obtained 0,758 with sig. (2 tailed) 0,00, it could be concluded that between the use of Game-Based Learning (Baamboozle) and students’ learning motivation had significant relationship
The Analysis of the implementation and criticism of the teaching campus program in improving the soft skills of islamic religious education students
Authors: Sanuhung Fitriyani , Muh. Wasith Achadi  , Aisah Nur Ilfi
Published: January 2025

The MBKM policy is one of the policies created by the government, especially the Indonesian education minister, to answer the needs of students in the 4.0 era where technological progress is very rapid. One of the programs of this policy is a teaching campus which provides a platform for students to study and improve their abilities for 4-6 months outside the university or campus environment. This research aims to find out how the teaching campus program is implemented, and also to criticize this program because there are several obstacles that exist in the implementation of the teaching campus program. This research method uses a qualitative method with a critical analysis approach, by collecting data through interviews and documents. The results of the research show that the implementation of the campus teaching program has gone well because from this program students' literacy and numeracy levels have increased, apart from that, students' abilities regarding self-confidence to speak in front of many people have also increased. It's just that there are still several obstacles that occur in the field.
Private university policy in formulating the KKNI for islamic religious education
Authors: Lola Lola Pitaloka , Muh. Wasith Achadi  , Yeni Wulandari
Published: January 2025

The purpose of this study is to see how the policy of private universities in formulating KKNI, the basic theory related to KKNI explains the statement of the quality of Indonesian Human Resources (HR) whose qualification levels are based on the level of ability stated in the formulation of learning outcomes. Universities as producers of educated HR need to measure their graduates, whether the graduates produced have 'abilities' equivalent to the 'abilities' (learning outcomes) that have been formulated in the KKNI qualification levels. This study uses a Qualitative research method. The data sources used in this study are primary data and secondary data, in the primary data there is an interview with the secretary of LPM STIT Makrifatul Ilmi Bengkulu Selatan, in the secondary data there is KKNI data that has been recorded. This study uses data collection techniques, namely interviews, documentation and observation with data analysis techniques, namely Data Reduction, Data display/data presentation and drawing conclusions on the results of the study in the interview with the secretary of LPM STIT Makrifatul Ilmi Bengkulu Selatan. The work management of LPM is structured, LPM and Quality Group design the mapping of courses, learning outcomes, course achievements and study program achievements and mapping of course studies. But in the concept of campus management, which requires every decision to coordinate with the Makrifatul Ilmi foundation institution, this is what makes the fiqh material courses and fiqh learning in madrasahs not revised as needed because the foundation institution does not give permission to make revisions to the KKNI in conclusion in this study explains the formulation of KKNI at the Makrifatul Ilmi Bengkulu Selatan Tarbiyah College of Science in the conclusion of this study was found in the interview data of the secretary of LPM STIT Makrifatul Ilmi Bengkulu Selatan, that the work management of LPM is structured, LPM and Quality Group design the mapping of courses, learning outcomes, course achievements and study program achievements and mapping of studies.
Religious Character Education Using a Compassion Approach: A Case Study at Baitul Qurro' Wal Huffadz Darusshomad Islamic Boarding School
Authors: Mardiah Siti Abidatul , Muh. Wasith Achadi  , Muhammad Shalahuddin Al Awwaby
Published: January 2025

This article is a case study design using a critical analysis method oriented towards a qualitative approach. The problems in this article are first, what is the background of the establishment of the Baitul Qurro' Wal Huffadz Darusshomad tahfidz boarding school. Second, how are the forms of affection approach as one of the religious character education programmes of students at PONPES Baitul Qurro' Wal Huffadz Darusshomad. Third, what are the obstacles in implementing this form of affection in implementing religious character education. The results of this study are: First, the concern of the founder of the pondok pesantern related to the character and morals of teenagers around his residence who are still far away in Islamic law. Second, the form of compassion approach as one of the religious character education programmes implemented there are two kinds, namely by applying habituation in good speech and applying the principle of equality for all parties in the Baitul Qurro' Wal Huffadz Darusshomad boarding school environment, so that none of the santri feel discriminated against. Third, the obstacles felt by educators such as, children influencing each other's bad treatment, for example teaching their friends to smoke, skip class, or even the existence of seniority between them.
Literacy house as a means of fostering the people: strategies for increasing islamic-based reading interest
Authors: Hanifah Noviandari  , Mohd Nazri bin Abdul Rahman
Published: January 2025

The background of this research is the low interest in reading the community, which is a challenge in building an Islamic literacy culture in the village. The purpose of the study is to find out the strategies that can be implemented, as well as to identify the supporting and inhibiting factors. The research method is qualitative with a phenomenological approach. Data were collected through interviews, observations, and documentation, and analysed using Miles, Huberman, Saldana's interactive model analysis techniques and applying Henry Mintzberg's 5P Theory. The results of the study show that the Sidoharjo Village Literacy House has succeeded in increasing people's interest in reading with a 5P theory-based strategy. Careful planning is well implemented. The tactics are carried out by Islamic fairy tale competitions, and social media campaigns. A pattern of reading habits that continues to be developed consistently. The strategic position of the Literacy House as a center for non-formal literacy and perspectives that respect local values also strengthens the attractiveness of the program, increasing citizen participation and ownership. Supporting factors include needs surveys and cooperation with local publishers, selection and procurement of structured reading materials, improvement of library facilities and interactive activities, evaluation and feedback collection. In addition, the inhibiting factors include a lack of awareness and limited knowledge about the benefits of reading, limited collections, lack of literacy education, budget limitations, and inadequate information technology infrastructure. The contribution of this research is to provide a model of a strategy for increasing reading interest that can be applied in other regions, as well as to recommend collaboration between the government, the community, and educational institutions to build a strong Islamic-based reading culture in the community.
The influence of positive psychology on PAI (Islamic Education) learning on social behavior and empathy among students
Authors: Fitriana Setiawati  , Wasith Achadi
Published: January 2025

This research aims to examine the influence of positive psychology in Islamic Religious Education (PAI) learning on the development of students' social behavior and empathy. This type of qualitative research uses the method of literature review by analyzing various literature, scientific journals, books and related documents. Positive psychology offers an innovative approach that is in line with PAI values, such as gratitude (Grattiude), compassion, mindfulness, and empathy, which can support student character formation. The research results show that the integration of positive psychology in PAI learning can improve students' ability to understand other people's feelings and show better prosocial behavior. This research recommendation includes the development of a PAI curriculum based on positive psychology to create more effective and meaningful learning.
Explanatory factor analysis on islamic education teachers’ level of technological pedagogical content knowledge (TPACK) at primary schools
Authors: Abd. Khaliq
Published: January 2025

This study aims to measure teachers’ Technological Pedagogical Content Knowledge (TPACK) level and analyze the factors that influence their TPACK level. It was conducted at Islamic primary schools in Gresik Regency, East Java, Indonesia. Involving 246 teachers as a sample, this study employed a mixed-method approach, combining quantitative and qualitative analysis. Quantitative data were analyzed using descriptive analysis and Structural Equation Modeling (SEM) to identify the relationships between variables affecting TPACK. Meanwhile, qualitative data were obtained through in-depth interviews with several teachers to understand their context and experiences in applying TPACK. The results showed that factors such as technology training, institutional support, professional teaching certification, and personal motivation significantly influenced the TPACK level of teachers. These findings provide important insights for the development of more effective training programs and enhanced institutional support to improve teachers' TPACK, aiming to facilitate more interactive and meaningful learning.
The integration of character education in junior high schools during the 5.0 industrial revolution: a case study in Yogyakarta
Authors: Roidah Lina  , Qiyadah Robbaniyah
Published: January 2025

This research examines the application of character education values ​​in the Industrial Revolution 5.0 era at four junior high schools in Yogyakarta: SMP Negeri 2 Wonosari, SMP Muhammadiyah 1 Yogyakarta, SMPN 2 Berbah, and MTS Islamic Education Center Muharrikun Najaah. Using qualitative methods and case studies, data was collected through interviews, observation and documentation. The results of the research are that SMP Negeri 2 Wonosari, SMP Muhammadiyah 1 Yogyakarta, SMP Negeri 2 Berbah, and MTS Islamic Education Center Muharrikun Najaah have made great efforts in implementing the values ​​of character education in the 5.0 era with various strategies and challenges faced. At SMP Negeri 2 Wonosari, the emphasis on technological adaptation and social dynamics supports character education that is relevant in the digital era, despite facing resistance from students and parents. SMP Muhammadiyah 1 Yogyakarta implements the values ​​of faith and piety, mutual cooperation, creativity and critical thinking through the independent curriculum program, even though the challenges of globalization and social media remain. At SMP Negeri 2 Berbah, the application of character values ​​through daily and extracurricular activities faces the challenges of cultural adaptation and limited resources, while MTS Muharrikun Najaah emphasizes character formation through religion and technology-based education, although digital influences and globalization remain obstacles. Each school shows a positive reflection in student attitudes and behavior that reflects the character values ​​taught, although challenges remain in the process of internalizing these values ​​in an era that continues to develop.The study highlights practical implications for enhancing character education. Schools are encouraged to integrate technology with localized cultural values, provide enhanced teacher training in digital pedagogy, actively involve parents, and establish community partnerships to address resource constraints. Policymakers must support efforts to align character education with the demands of the 5.0 era, ensuring its relevance and sustainability. This research offers valuable insights into how schools can adapt and innovate to embed character education effectively within the evolving educational landscape. By focusing on targeted strategies and addressing contextual challenges, educators and stakeholders can ensure the continued significance of character education in an era shaped by globalization and digital transformation.
Character education as the foundation of vocational curriculum: a case study at SMK Mardhotullah Al-Islamy
Authors: Eko Ngabdul Shodikin  , Shafira Azzahra  , Tamami Muhammad Zaki
Published: January 2025

Character education has become a major focus in the education system in Indonesia, particularly in vocational schools. This study examines the integration of character education into the vocational curriculum at SMK Mardhotullah Al-Islamy, aiming to assess the impact of implementing the Panca Jiwa and Panca Karakter values on shaping students' character, balancing technical competence and moral integrity. This research uses a qualitative approach with a case study method. Data were collected through interviews with teachers, field observations, and analysis of curriculum documents and program implementation. Data analysis was conducted descriptively to describe the implementation and impact of character education in the vocational school context. The results show that the integration of character education into the vocational curriculum at SMK Mardhotullah Al-Islamy has successfully shaped students who are not only technically competent but also possess high moral values. The role of teachers as Ruhul Mudarris and the supportive school environment contributed significantly to the success of the program. Challenges encountered in the implementation of the program include time constraints, varying levels of understanding among teachers, and the socio-economic backgrounds of students. This study recommends that this approach be adapted by other vocational schools in Indonesia, with adjustments to local contexts
Review of gender-responsive sex education material and methods in the context of islamic education
Authors: Luluk Ifadah  , Yuni Setya Hartati  , Dea Puji Saputri  , Puput Sukma Ayu Wulandari  , Mohamad Ardin Suwandi
Published: January 2025

The discussion of material and methods for gender-responsive sex education is an important issue within the context of Islamic education, approached with sensitivity to gender differences. This study aims to explore how sex education can be aligned with Islamic teachings that emphasize moral values, ethics, and gender justice. The study finds that the material for sex education in Islamic education must encompass aspects of reproductive health, ethics of inter-gender relationships, and the value of purity in Islamic teachings. Additionally, the teaching methods applied should be sensitive to gender issues, avoiding stereotypes, and providing equal space for both men and women in understanding sexuality. This research also identifies various challenges, such as conservative perceptions in society and the unpreparedness of parents as educators in delivering sex education materials. It can be concluded that, with the appropriate materials and methods, gender-responsive sex education in Islamic education will contribute to the development of individuals who are healthy physically, mentally, and spiritually, while respecting the values of gender equality and justice.
Character education based on islamic inheritance law: a contextual strategy to address modern moral challenges
Authors: Sulistyo Agus , Nur Faizah Enik , Ryadhush Shalihin Rahmat
Published: January 2025

This study aims to explore the potential integration of Islamic inheritance law, particularly the concept of murder as a disqualifier for inheritance rights (māni’ al-mīrāṡ), as a medium for character education within the Islamic Religious Education (PAI) curriculum. Family conflicts over inheritance disputes, often culminating in acts of murder, provide a critical context for connecting moral values such as justice, responsibility, and respect for life to ethics-based learning. This approach innovatively employs the normative concepts of Islamic law as a character development tool, addressing the modern era's moral challenges. The study adopts a qualitative-descriptive methodology, incorporating analyses of Islamic law literature and character education frameworks. Primary sources include the Qur’an, Hadith, and classical jurisprudential texts such as Al-Mughni by Ibn Qudamah and Al-Ahkam As-Sulthaniyyah by Al-Mawardi. Secondary sources encompass literature on character education and learning strategies. Content analysis is employed to identify the moral values inherent in Islamic inheritance law and their relevance to character education using case-based studies. The findings indicate that Islamic inheritance law can effectively function as a tool for character education, fostering values such as self-control, respect for life, and ethical conflict resolution. Case-based learning and problem-based learning (PBL) approaches prove effective in integrating these themes into the moral and religious character formation of students. This study offers a novel, contextual, and practical approach distinct from conventional teaching methods, addressing the increasingly complex moral challenges posed by materialism and individualism in society.
Temel Radyofarmasi
Authors:   Moleküler Görüntüleme ve Teranostik Merkezi, Missouri Universitesi, Columbia, Missouri, Amerika, Ocak Meltem
Published: January 2025

Radyofarmasötikler, nükleer tıp uygulamalarında hastalıkların tanı ve tedavisinde kullanılan
radyoaktif ilaçlardır. Tanı amaçlı kullanılan radyofarmasötiklerin çogu gamma veya pozitron yayan radyonüklitler kullanılarak hazırlanırken, tedavi radyofarmasotikleri çoğunlukla beta (β-)
veya alfa (α) gibi partiküler radyasyon yayan radyonüklitler ile hazırlanır. Son yıllarda, farklı
radyofiziksel özelliklere sahip olan aynı elementin iki radyonükliti veya farklı radyonüklitlerin
benzer veya aynı biyomoleküllerle kompleksler oluşturarak moleküler görüntüleme ve tedavi
amaçlı kullanımları da yaygınlaşmaktadir. Bu tür uygulamalar, 2000’li yıllarda tıp literatüründe “teranostik” uygulamalar olarak anılmaya başlanmış ve günümüzde kişiselleştirilmiş tıp
uygulamalarının bir örneği haline gelmiştir. İdeal radyofarmasötikler kolay temin edilebilmeli,
kolay hazırlanabilmeli, ucuz olmalı, farmakolojik etki göstermemeli, toksik olmamalı ve hedefte olabildiğince seçici ve yüksek miktarda birikmelidir. Radyofarmasötiklerin etkin ve güvenilir
bir şekilde hazırlandığından emin olmak için, her ülkenin kendi farmakopesi veya takip edilen
(Avrupa Farmakopesi, Amerika Farmakopesi gibi) farmakopelerin standartlarına uygun olarak
hazırlanması zorunludur.
Gastrointestinal Sistem ve Hepatobilier Sistem Sintigrafileri
Authors:   İstanbul Üniversitesi-Cerrahpaşa, Cerrahpaşa Tıp Fakültesi Nükleer Tıp Ana Bilim Dalı, İstanbul, Türkiye, Asa Sertaç
Published: January 2025

• Tükürük bezi sintigrafisi, Sjögren sendromu, sialolitiazis ve bazı radyonüklit tedaviler sonrası tükürük bezi fonksiyonlarını değerlendirmek için kullanılır. Özefagus transit zamanı
sintigrafisi, sistemik sklerozis gibi hastalıklarda erken tanı ve hastalık takibi için güvenilir
ve tekrar edilebilir bir yöntemdir. Ayrıca gastroözefageal reflünün izlenmesi, reflü özofajit
ve özefagus motilite bozukluklarının nedenlerinin anlaşılmasında önemlidir.
• Gastroözefageal reflü sintigrafisi, %90’a varan duyarlılıkla invaziv olmayan bir yöntemdir
ve akciğerlere aspirasyonu gösterebilir. Mide boşalım sintigrafisi ise diyabetik gastroparezi
değerlendirilmesinde kullanılır.
• Eritrosit işaretli kanama sintigrafisi, düşük hacimli kanamaları tespit edebilir ve aralıklı
kanamalar için başarılıdır. İn vitro yöntemle eritrositlere radyoaktif maddenin bağlanma
verimliliği %98’dir. Gastrointestinal kanama sintigrafisinde SPECT/BT, cerrahi öncesi odak
tespiti için faydalıdır.
• Meckel divertikülü sintigrafisinin pozitifliği hematokezya, iki yaşından küçük hasta ve düşük hemoglobin düzeyi ile artar. Safra yolları sintigrafisinde bağırsak aktivitesinin gözlemlenmesi, biliyer atrezinin dışlanması için kritiktir. Akut kolesistitte 4. saatte safra kesesi
aktivitesinin olmaması tanıyı doğrular. Morfin kullanılarak tanı süresi kısaltılabilir.
• Splenozis veya aksesuar dalak tespiti için selektif dalak sintigrafisi kullanılır.
İskelet Sistemi Sintigrafileri
Authors:   İstanbul Üniversitesi-Cerrahpaşa, Cerrahpaşa Tıp Fakültesi, Nükleer Tıp Ana Bilim Dalı, İstanbul, Türkiye, Uslu Beşli Lebriz
Published: January 2025

Kemik sintigrafisi (KS), kemikte kanlanma artışı ve osteoblastik değişiklikleri göstererek kemiklerin metabolizması hakkında bilgi verir. Kemiklerde henüz anatomik değişikliğin oluşmadığı, bu nedenle radyolojik görüntüleme yöntemlerinin bulgu vermediği erken safhadaki pek çok
kemik lezyonu kemik sintigrafisi ile kolayca ayırt edilebilir. Kemik sintigrafisinde hidroksiapatit
kristallerine bağlanan Tc-99m işaretli difosfonat türevleri veya daha az sıklıkla F-18 sodyum
florür kullanılır. Kemik metastazlarının saptanması, tedavi yanıtının değerlendirilmesi, primer
kemik malignitelerinin evrelemesi, stres fraktürlerinin tanısı, protez enfeksiyonlarının araştırılması, avasküler nekroz gibi farklı pek çok endikasyonda kemik sintigrafisi kullanılır. Kemik
iliği sintigrafisi ise kemik iliğinin durumu, aktivitesi, kemik iliğini infiltre eden hastalıkların ve
kemik iliği enfarktının tayini ve kemik enfeksiyonlarının ayırıcı tanısı amacıyla yapılır ve retiküloendotelyal sistemi hedef alan radyoaktif işaretli kolloidler kullanılır. Kemik mineral yoğunluğunu ölçmek ve bu sayede osteopeni veya osteoporoz tanısını koyabilmek için altın standart
yöntem Dual Enerji X-ışını Absorbsiyometri (DEXA)’dır.
Beyin ve Baş-Boyun Tümörlerinde PET Görüntüleme
Authors:   İstanbul Üniversitesi-Cerrahpaşa, Cerrahpaşa Tıp Fakültesi Nükleer Tıp Ana Bilim Dalı, İstanbul, Türkiye, Sağer Sait
Published: January 2025

Primer beyin tümörlerinde ve baş-boyun tümörlerinde PET/BT görüntülemesi tanı, evreleme,
tedaviye yanıt değerlendirme amacıyla yaygın olarak kullanılmaktadır. Bu amaçla en çok kullanılan radyofarmasötik F-18 ile işaretli FDG olup, bunun yanı sıra diğer PET ajanları olan reseptör görüntülemesi, aminoasit sentezi, DNA sentezi, hücre zarı sentezi, hipoksi görüntülemesi
gibi yeni yöntemler de yaygınlaşarak kullanılmaktadır.
Akciğer Kanserlerinde PET Görüntüleme
Authors:   İstanbul Üniversitesi-Cerrahpaşa, Cerrahpaşa Tıp Fakültesi Nükleer Tıp Ana Bilim Dalı, İstanbul, Türkiye, Sayman Haluk Burçak
Published: January 2025

Akciğer kanserinin tanısında kullanılan yöntemler arasında F-18 FDG ile yapılan pozitron emisyon tomografisi (PET) önemli bir yer alır.
Bu amaçla yapılan PET/BT incelemeleri yalnızca primer tümörü incelemek için değil aynı zamanda olası uzak metastazları saptamak amacı ile verteksten femoral bölgeye kadar tüm vücut
tarama şeklinde yapılır.
F-18 FDG PET/BT, tanı amaçlı transtorasik biyopsi işlemine de yol göstericidir.
F-18 FDG PET/BT, akciğer kanserlerinde evreleme, nükslerin belirlenmesi ve yeniden evreleme, tedaviye cevabın araştırılması, radyoterapi planlama, prognoz öngörme amacı ile kullanılır.
Kemik ve Kemik İliği Malignitelerinde PET Görüntüleme
Authors:   İstanbul Üniversitesi-Cerrahpaşa, Cerrahpaşa Tıp Fakültesi Nükleer Tıp Ana Bilim Dalı, İstanbul, Türkiye, Uslu Beşli Lebriz
Published: January 2025

F-18 FDG PET görüntüleme, primer kemik sarkomlarının evrelemesinde, tedavi yanıtının
değerlendirilmesinde ve takip döneminde nüks hastalığın saptanmasında yaygın olarak kullanılmaktadır. Birçok kemik sarkomu yoğun FDG tutulumu gösterirken bazı kemik sarkomları
(genellikle düşük grade’li olanlar) düşük düzeyli FDG tutulumu gösterir ve tümörün agresifliği
ile FDG tutulumu arasında genellikle pozitif korelasyon vardır. FDG PET multipl myelom lezyonlarını göstermede yüksek duyarlılık ve özgüllüğe sahiptir. Diğer konvansiyonel yöntemlerden
farklı olarak aktif miyelom lezyonlarını inaktif lezyonlardan ayırt edebilir, hastalık remisyonunu
ve relapsını gösterebilir, ve ekstramedüller hastalığı görüntüleyebilir. Kemik metastazlarının
gösterilmesinde FDG haricinde F-18 sodyum florür (NAF), Ga-68 veya F-18 işaretli PSMA, Ga68 işaretli oktreotid analogları, F-18 DOPA, F-18 floroöstrodiol (FES) gibi birçok farklı PET radyofarmasötiği de kullanılmaktadır
Tiroit Kanserlerinde İyot-131 (I-131) Tedavisi
Authors:   İstanbul Üniversitesi-Cerrahpaşa, Cerrahpaşa Tıp Fakültesi Nükleer Tıp Ana Bilim Dalı, İstanbul, Türkiye, Sayman Haluk Burçak
Published: January 2025

Tiroit kanserleri arasında en sık %95 oranı ile papiller tiroit kanseri görülür. Bunu folliküler
(%4,5) ve Hürthle (%1,8) hücreli kanserler ile parafoliküler C hücrelerinden kaynaklanan medüller tiroit (%1,6) kanseri izler. Ayrıca tiroidin az görülen indifferansiye anaplastik (%0,8) kanseri de vardır.
Bu kanser tipleri arasında differansiye tiroit kanserlerin tedavisinde tam ya da tama yakın tiroidektomi sonrasında bazı özel kriterler gözetilerek uygun bulunan, yüksek riskli hastalarda
İyot-131 (I-131) ile radyoaktif iyot tedavisi (RAİ) yapılması gerekir.
Bu amaçla ß-
ışıması yapan I-131 kullanılır ve işleme remnant ablasyonu adı da verilir. Papiller,
foliküler varyant papiller tiroit kanserleri ve foliküler kanserler büyük çoğunluğunda I-131 tutulur. Hürthle hücreli tiroit kanserlerinde ise genellikle düşük yoğunlukta I-131 tutulumu olur.
Foliküler tiroit kanserinde I-131’in etkili olabilmesi için iyot simportörüne sahip olması ve iyotu
alması gerekir.
Medüller tiroit kanserlerinde ve indifferansiye kanserlerde I-131 tutulmayacağından ablasyon
tedavisi etkisizdir.
Total tiroidektomi sonrası bakiye dokunun ilk I-131 ablasyonu ve/veya lokal bölgesel tedavi için
ya tiroit hormon ilacı kesilerek endojen TSH yükselmesi (>30 mU/l) sağlanır ya da art arda 2
günlük intramüsküler tirotropin alfa (rhTSH) enjeksiyonu ile ekzojen TSH kullanılır.
Total tiroidektomiyi ve rezidüel hastalığın mevcut olup olmadığını değerlendirmek için ameliyattan sonra tanısal tüm vücut I-131 görüntülemesi önerilir.
Karaciğer Malignitelerinde İntrahepatik Arteryel Radyoembolizasyon Tedavisi
Authors:   İstanbul Üniversitesi-Cerrahpaşa, Cerrahpaşa Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Nükleer Tıp Ana Bilim Dalı, İstanbul, Türkiye, Sönmezoğlu Kerim
Published: January 2025

Radyoembolizasyon (RE) tedavisi, hepatik arterden beta ışıması yapan radyoaktif mikroküreler verilerek uygulanan ve cerrahi rezeksiyon şansı bulunmayan primer ve metastatik
karaciğer malignitelerinde yaygın kullanılan etkin bir lokal tedavi seçeneğidir.
• RE tedavisine uygun aday olduğu düşünülen hastalarda tedavi seansından önce prova anjiyografisi ve Tc-99m MAA ile hepatik perfüzyon sintigrafisi yapılması hayati önem taşır. Bu
çalışmada karaciğer vasküler anatomisinde tedaviyi etkileyebilecek varyasyonların belirlenmesi, tümör alanını en iyi besleyen hepatik arter dalının bulunması, tümörün kanlanma
özelliklerinin ortaya konması, karaciğer dışına kaçışların tespit edilmesi amaçlanır. Gastrointestinal sisteme kaçış olması durumunda buna neden olan arterin koille kapatılması elzemdir. Aksi taktirde tedavide böyle bir kaçış ölümcül komplikasyonlara yol açabilmektedir.
• RE tedavisinden sonra radyoaktif mikrokürelerin dağılımı sintigrafik görüntüleme yapılarak değerlendirilir. Çok büyük oranda beta ışıması yapan Y-90 ile yüksek kalitede sintigrafik görüntüleme yapmak güçtür. Genellikle Y-90’ın minimal pozitron ışımasından yararlanılarak PET görüntüleme ya da Y-90’ın dokudan geçerken oluşturduğu sekonder x-ışınları
(Bremsstrahlung) kullanılarak düşük kalitede SPECT görüntüleme yapılır.
• Yapılan klinik araştırmalarda RE tedavisinin hem primer karaciğer malignitelerinde hem
de metastatik karaciğer hastalığında tüm evrelerde birinci basamak tedavide rutin tedavilere kombine olarak veya kurtarma tedavisinde tek başına veya kombine olarak güvenle
kullanılabileceğini ortaya koymuştur. Fiziksel performansı ve hepatik rezervi iyi olan ve karaciğer dışı metastazı olmayan hastalarda daha iyi progresyonsuz sağ kalım ve genel sağ
kalım süreleri elde edilebilmektedir. Bir grup hepatosellüler kanser hastası RE tedavisi ile
transplantasyona uygun hale getirilebilmekte (köprü tedavisi) ve diğer bir kısım metastatik
hasta ise cerrahi rezeksiyona uygun hale gelebilmektedir
Radyosinovektomi
Authors:   İstanbul Üniversitesi-Cerrahpaşa, Cerrahpaşa Tıp Fakültesi Nükleer Tıp Ana Bilim Dalı, İstanbul, Türkiye, Uslu Beşli Lebriz
Published: January 2025

Radyosinovektomi, sinovit ile seyreden ve eklem ağrısına sebep olan birçok hastalıkta eklem
ağrısını ve hareket kısıtlılığını gidermek için kullanılan bir intraartiküler lokal radyonüklit tedavi
yöntemidir. Radyosinovektomide enflame sinoviyal membranda tutularak membranı ışınlayan
ve çoğunlukla kolloid ile bağlanmış özel radyonüklitler intraartiküler olarak enjekte edilir. Bu
kolloid içeren radyoaktif partiküller, enflame sinoviyal membrandaki makrofajlar tarafından fagosite edilerek membranda tutulur, yaydıkları beta partikülleri membranda koagülasyon nekrozuna yol açar, bu sayede sinoviyal membran incelir ve enflamasyon azalır. Hastaların yaklaşık
%60-80’i tedaviye cevap verir ve genellikle tedavi cevabı uygulamadan 2-4 hafta sonra görülür.
Geçmişten Geleceğe Mekanik Ahşap Teknolojisi Alanındaki Gelişmeler
Authors:   İstanbul Üniversitesi-Cerrahpaşa, Orman Fakültesi, Orman Endüstri Mühendisliği Bölümü, Odun Mekaniği ve Teknolojisi Ana Bilim Dalı, İstanbul, Türkiye, Dündar Türker , Görgün Hızır Volkan ,   İstanbul Üniversitesi-Cerrahpaşa, Orman Fakültesi, Orman Endüstri Mühendisliği Bölümü, Odun Mekaniği ve Teknolojisi Ana Bilim Dalı, İstanbul, Türkiye, Kurul Fatih ,   İstanbul Üniversitesi-Cerrahpaşa, Orman Fakültesi, Orman Endüstri Mühendisliği Bölümü, Odun Mekaniği ve Teknolojisi Ana Bilim Dalı, İstanbul, Türkiye, Avşar Esra Yıldız ,   İstanbul Üniversitesi-Cerrahpaşa, Orman Fakültesi, Orman Endüstri Mühendisliği Bölümü, Odun Mekaniği ve Teknolojisi Ana Bilim Dalı, İstanbul, Türkiye
Published: January 2025

Bu çalışma kapsamında Türkiye Cumhuriyeti’nin ilk yüzyılında, fiziksel ve mekanik ahşap teknolojisi alanındaki gelişmeler ortaya konulmaya çalışılmıştır. Genel olarak ahşap ve ahşap esaslı
malzeme üretimi, modifikasyonu, karakterizasyonu gibi konuların yer aldığı bu alanda, tarih içerisinde yaşanan gelişmeler sıralanmıştır. Aynı zamanda bu gelişim sürecinde İstanbul Üniversitesi-Cerrahpaşa Orman Fakültesi, Orman Endüstri Mühendisliği Bölümü, Odun Mekaniği ve
Teknolojisi Anabilim Dalı’nda gerçekleştirilen bilimsel ve endüstriyel çalışmalara da değinilerek,
bu alanda Türk akademisine yapılan katkılara da yer verilmeye çalışılmıştır.
Cumhuriyetimizin 100. Yılında Peyzaj Mimarlığı Eğitim ve Öğretimi
Authors:   İstanbul Üniversitesi-Cerrahpaşa Orman Fakültesi Peyzaj Mimarlığı Bölümü, Peyzaj Teknikleri Ana Bilim Dalı, İstanbul, Türkiye, Ekşi Mert
Published: January 2025

Peyzaj mimarlığı; doğal ve kültürel kaynaklar ile fiziksel çevreyi bilimsel ilkeler çerçevesinde ele
alan, arazi planlaması, tasarımı, yönetimi, korunması ve onarılması konularını kapsayan bir planlama ve tasarım bilim ve sanatı olarak tanımlanmaktadır. Peyzaj mimarlığı lisans eğitim ve öğretimi, dünyada ilk olarak 1900 yılında Amerika Birleşik Devletleri’nde, Harvard Üniversitesi’nde
başlamıştır. Ülkemizde ise peyzaj mimarlığı eğitim ve öğretiminin temelleri 1930’lu yıllara kadar
uzanmaktadır. 1968 yılında Ankara Üniversitesinde eğitim ve öğretim sürecinin başlamasıyla
resmi bir kimlik kazanan süreç, ülkemizdeki diğer programların açılması ile devam etmiştir. 1984
yılında ülkemizin ikinci peyzaj mimarlığı bölümü olarak fakültemizde kurulan Peyzaj Mimarlığı
Bölümü, 1985 yılında eğitim ve öğretime başlamıştır. Bölümümüz, 1989 yılında Türkiye’de peyzaj
mimarı meslek unvanı ve diploması veren ilk bölüm olarak mezunlarını vermiştir. 21. yüzyılda
peyzaj mimarlığı mesleği; ev bahçelerinden kent parklarına, kentsel yeşil alan sistemlerinden
kırsal gelişim projelerine kadar çok geniş bir yelpazeyi kapsayan bir meslek dalıdır. Bu kapsamda, bölümümüz doğal ve kültürel peyzajların sürdürülebilirlik ilkeleri çerçevesinde korunması,
onarımı, planlanması, tasarımı ve yönetiminde katkılar sunan peyzaj mimarları yetiştirmeyi hedeflemektedir. Bu çalışmada İstanbul Üniversitesi – Cerrahpaşa Peyzaj Mimarlığı Bölümümün
geçmişi ile peyzaj mimarlığı alanındaki gelişmelere yönelik bir değerlendirme sunulmuştur
Implementing Blockchain for Secure and Efficient Cross-Border Payment Systems
Authors: Sule Aumbur Kwaghter , Eyo-Udo Nsisong Louis , Onukwulu Ekene Cynthia , Agho Mercy Odochi , Azubuike Chima
Published: January 2025

The global financial ecosystem has long been hindered by inefficiencies, high costs, and security concerns in cross-border payment systems. Blockchain technology has emerged as a promising solution to address these challenges, offering enhanced security, transparency, and operational efficiency. This paper explores the potential of blockchain for transforming cross-border payment systems, focusing on its role in improving transaction speed, reducing costs, and ensuring the integrity of data. Blockchain’s decentralized nature eliminates intermediaries, reducing transaction times from days to minutes, which is particularly crucial for international money transfers. One of the key advantages of blockchain in cross-border payments is its ability to provide a transparent and immutable ledger, ensuring the traceability of transactions. This enhances security by making fraud and errors less likely, as all records are permanently stored in a distributed ledger accessible by all parties involved. Smart contracts, another feature of blockchain, enable automatic execution of predefined agreements, reducing the need for manual intervention and streamlining operations. Furthermore, blockchain facilitates the integration of digital currencies and stablecoins, providing an alternative to traditional currency exchange methods and minimizing the risks associated with fluctuating exchange rates. By utilizing cryptocurrencies or digital tokens, blockchain-based systems can reduce the dependence on correspondent banks, thereby minimizing transaction fees and delays. Despite its numerous advantages, there are challenges to blockchain adoption in cross-border payments, including regulatory compliance, scalability, and integration with existing financial infrastructure. However, ongoing advancements in blockchain protocols and regulatory frameworks are progressively overcoming these barriers, paving the way for broader implementation. This paper examines real-world case studies of blockchain applications in cross-border payments, demonstrating its impact on financial inclusion and international trade. The findings suggest that blockchain has the potential to revolutionize the global payment system by making cross-border transactions more secure, efficient, and cost-effective.
Organizational (Re-)Configurations of Introducing Medical Innovations into Sustainable Practice: The Case of TAVI
Authors: MASOVIC Jasmina , VARGOVIC Emil , MILOVANOVIC Bojan MORIC
Published: January 2025

This study explores the adoption of Transcatheter Aortic Valve Implantation (TAVI) at a Norwegian university hospital, with an emphasis on the organizational and relational dynamics required to sustain new medical innovations in long-term practice. The article highlights a lack of empirical studies on the early-phase relational configurations and negotiations necessary for sustaining new procedures in healthcare. Employing a five-year ethnographic case study approach, we gathered data through direct observations and semi-structured interviews involving multiple stakeholders, including medical practitioners, managers, technology vendors, and many others. Our findings reveal that sustaining TAVI as a standard practice required establishing relational configuration among multidisciplinary stakeholders, balancing collaborative learning with jurisdictional boundaries. A notable outcome was the division of the TAVI team into sub-groups, facilitating specialization and enhancing procedural efficiency, thus promoting TAVI’s routinization. These findings contribute to a relational framework for understanding how early stakeholder configurations and collaborative patterns affect the sustainability of healthcare innovations.
Theoretical Background on Valuation Methods of Intangible Assets in Listed and Unlisted Companies: A bibliometric analysis from 2010-2024
Authors: BUTNARU (CIOBOTAR) Alina
Published: January 2025

The study is oriented to observe the theoretical issues regarding the perception of intangible assets in listed and unlisted firms. The market, cost or income approaches are the main techniques for the valuation of intangibles in listed and unlisted firms, and the influencing factors of this process include: corprorate governance policies, the profitability of the firm or ownership structure. The bibliometric analysis showed that the number of papers dealing with the valuation of intangibles in listed firms is much higher than in unlisted firms, due to the fact that listed firms provide more complex data due to the mandatory disclosure of financial statements. It is possible that unlisted firms, although an important link in the global economy, consider the financial effort to be too great to meet the listing requirements. It should be noted that a correct evaluation of intangible resources can lead to more efficient management and investment targeting that can generate major future benefits. The study is also a signal of the growing importance of the contribution of intangibles to the total value of firms, and the need for a regulatory framework for the valuation of intangible assets should ensure a minimum degree of comparability, transparency and reasoned delineation.
GANGGUAN MOOD PADA ANAK DENGAN IBU KEPRIBADIAN AMBANG: LAPORAN KASUS
Authors: NEGARA NI WAYAN WIRAYANTI PUTRI , ARDANI I GUSTI AYU INDAH , WINDIANI I GUSTI AYU TRISNA , ADNYANA I GUSTI AGUNG NGURAH SUGITHA
Published: January 2025

ABSTRACT
Childhood is an important phase in personality formation, but it is often accompanied by psychological problems that affect child development. Child development is greatly influenced by various factors, including parenting patterns. Data in this case study were obtained through in-depth interviews, medical records and psychometric examinations and projection tests aimed at seeing how mood disorders in children who have mothers with borderline personality. The patient is a 9-year-old boy who shows symptoms of aggression, hallucinations, unstable moods, and feelings of emptiness and loneliness. The child in this case shows problems with emotional dysregulation due to inconsistent parenting and environmental stress. The patient's mother has a borderline personality characterized by difficulty controlling emotions, extreme mood swings, and unstable behavior, which negatively affects parenting patterns. Studies show that mothers with borderline personality tend to create unstable environments, increase the risk of insecure attachment in children, and affect their emotional regulation. This case study highlights the importance of understanding the relationship between parental personality disorders and parenting, and their impact on child development. Interventions in parenting and support for families at risk of psychopathology can be preventive steps to reduce the incidence of mood disorders in children.
ABSTRAKMasa kanak-kanak adalah fase penting dalam pembentukan kepribadian, namun sering disertai masalah psikologis yang memengaruhi perkembangan anak. Perkembangan anak sangat dipengaruhi oleh berbagai faktor, diantaranya pola asuh orangtua. Data dalam studi kasus ini diperoleh melalui wawancara mendalam, catatan rekam medis dan pemeriksaan psikometri dan tes proyeksi yang bertujuan untuk melihat bagaimana gangguan mood pada anak yang memiliki ibu dengan kepribadian ambang. Pasien adalah anak laki-laki 9 tahun yang menunjukkan gejala agresivitas, halusinasi, mood yang tidak stabil, serta rasa hampa dan kesepian. Anak dalam kasus ini menunjukkan masalah disregulasi emosi akibat pola asuh yang tidak konsisten dan tekanan lingkungan. Ibu pasien memiliki kepribadian ambang yang ditandai dengan kesulitan mengendalikan emosi, perubahan suasana hati yang ekstrem, dan perilaku tidak stabil, yang memengaruhi pola pengasuhan secara negatif. Studi menunjukkan bahwa ibu dengan kepribadian ambang cenderung menciptakan lingkungan yang tidak stabil, meningkatkan risiko kelekatan yang tidak aman pada anak, dan memengaruhi regulasi emosinya. Studi kasus ini menyoroti pentingnya memahami hubungan antara gangguan kepribadian orang tua dan pengasuhan, serta dampaknya pada perkembangan anak. Intervensi pada pola asuh dan dukungan bagi keluarga dengan risiko psikopatologi dapat menjadi langkah preventif untuk menurunkan kejadian gangguan mood pada anak.
General Circulation Models evaluation at different time scales over tropical region using ESA-CCI satellite data records: a case study of water vapour and cloud cover
Authors: Ngoungue Langue Cedric Gacial , Brogniez Helene , Naveau Philippe
Published: January 2025

Abstract. Water vapour and cloud cover are two essential components of the earth's atmosphere. General circulation models (GCM) are used to study the long term evolution of the Earth's climate over past and future periods. The present work consists of assessing the representation of total column water vapor (TCWV) and total cloud cover (TCC) in the Atmospheric Model Intercomparison Project Phase 6 (AMIP6), the ERA5 reanalysis from the European Centre for Medium-Range Weather Forecasts (ECMWF), and satellite data records from the European Space Agency Climate Change Initiative (ESA-CCI). ESA-CCI is used as the reference for the common observation period with AMIP6, spanning from July 2003 to December 2014, to calibrate the framework. For the period prior to the observational period, from January 1981 to June 2003, ERA5 serves as the reference. This study is carried out over the tropical region which has been splitted in two sub-regions: the tropical oceans and tropical lands. The assessment of TCWV and TCC at different time-frequency is performed using a mathematical tool called "multi-resolution analysis" (MRA). By applying the MRA decomposition, we found that the AMIP6 models produce consistent evolution of TCWV and TCC at seasonal to interannual scales (from 2 months to 5.6 years) in the tropical region, even if the representation of the amplitude of TCC remains sometimes challenging. The evaluation of ESA-CCI TCWV and TCC variability in AMIP6 models reveals that the models do not perform well at daily and subseasonal scales. At seasonal to interannual scales, the models reproduce more accurate variability of TCWV and TCC with respect to ESA-CCI. However, AMIP6 models do not capture the trend in the evolution of ESA-CCI TCWV and TCC. The co-variations between TCWV and TCC were analyzed in the Nino3.4 region, revealing a significant positive correlation at the subseasonal scale, with a value of 0.7 for ESA-CCI and 0.3 for AMIP6. At seasonal to annual scales, we found a strong positive correlation between TCWV and TCC, with the exception of the CanESM5 and IPSL models, which showed a negative but significant correlation around -0.5.