bluuebunny/crossref_metadata_2025 huggingface dataset:
Cytomegalovirus infection of brain tumors and CMV immunotherapy
Authors: Lisianyi Mykola I. , Klyuchnikova Antonina I. , Lisianyi Oleksandr M. , Belska Liudmyla M. , Kot Larysa A. , Stanetska Diana M.
Published: November 2022

Objective. The article presents the literature of the last ten years and the results of our own research on the importance of cytomegalovirus (CMV) in the development of brain tumors, especially glioblastoma and medulloblastoma. Two alternative views are discussed - the pros and cons of the role of the virus in the induction and stimulation of tumor growth.Materials and methods. 256 samples of biotic material of tissues of various brain tumors were studied. Among them are histologically diagnosed: in 123 cases glial tumors of various grade of malignancy, in 51 cases meningiomas, in 25 cases medulloblastomas, in 16 cases oligodendroastrocytomas of the second grade of malignancy, in 14 cases metastatic tumors. Tumor fragments were obtained from biopsy material 1.5-2.0 hours after surgical removal. To detect the presence of CMV in the tumor tissue real-time polymerase chain reaction (PCR) using "DNA sorb A and B" kits was performed, the company "Amplisens" (Russia), according to the manufacturer’s instructions and BioRal device (USA) with standard DNA detection kits of CMV "DNA Technology" (Russia). Cytological imprints on slides were also made from tumor tissue fragments, which were examined by indirect immunofluorescence method with monoclonal antibodies to CMV pP-65 protein using the "MonoScan CMV" kit.Results. The frequency of detection of CMV antigen or its DNA in brain tissue depends on the research method - the immunofluorescence method detects pP-65 antigen by monoclonal antibodies 2-2.5 times more often than the PCR method of CMV in tumor tissue. In the tissue of different histogenesis of brain tumors both the pP-65 antigen and CMV DNA are detected with different frequencies. CMV was most often detected in tumors of glial origin and medulloblastomas. No CMV DNA was detected in the peripheral blood of patients with brain tumors at the time of admission for examination and surgical treatment, indicating an earlier contamination of the tumor focus with this virus. Data on the mechanisms of CMV induction and stimulation of tumor growth by activating cell proliferation, including nerve stem cells, are presented. Works using specific antiviral therapy and CMV specific cell immunotherapy in the treatment of gliomas have been analyzed in detail.Conclusions. The paper concludes on the important clinical and prognostic value of determining CMV infection in brain tumors and indicates the need for CMV viral and cellular immunotherapy in the combined treatment of malignant brain tumors.
Concentration-dependent characteristics of a complex coacervate
Authors: Li Hongwei , Porcar Lionel , Bentaleb Ahmed , Schatz Christophe , Chapel Jean-Paul
Published: November 2022

In this work, we have comprehensively and systematically investigated the influence of the initial concentration of oppositely charged polyelectrolyte solutions on the interaction strength, interfacial tension and local structure of the coacervate phase generated at charge stoichiometry in a PDADMAC/PANa model system. We have shown for the first time that the concentration has a direct and significant impact on the complexation strength between the two polyelectrolytes, leading to lighter coacervates with constant mass yield and increasing network mesh and decreasing liquid-liquid interfacial tensions until a critical concentration where oppositely charged chains no longer interact, generating the so-called self-supressed coacervate single phase (SSCV). An effect that is due the free counterions present in the solution, whose concentration increases with that of the PE polyelectrolytes and gradually screens the electrostatic complexation. These characteristics will certainly have an impact on the capacity of these coacervates, objects of great scientific and technical interest today, to be efficiently stabilized, to encapsulate active principles and to serve as bioreactors.
Water soluble chromenylium dyes for shortwave infrared imaging in mice
Authors: Jia Shang , Lin Eric , Lim Irene , Mobley Emily , Guo Lei , Sletten Ellen
Published: November 2022

In vivo imaging using shortwave infrared light (SWIR, 1000-2000 nm) benefits from deeper penetration depths, decreased background autofluorescence, and high resolution. However, the development of biocompatible contrast agents for these low energy wavelengths has significant challenges. While there have been significant advances in SWIR chromophore scaffolds over the past 5 years, a major barrier for widespread utility of SWIR small molecule fluorophores is their hydrophobicity and tendency to form non-emissive aggregates. Here, we report a platform for generating a panel of soluble and functional dyes for SWIR imaging by late-stage functionalization of a fluorophore intermediate via click chemistry. The resulting fluorophores with sulfonate, ammonium or zwitterion functionalities are all water soluble with bright SWIR fluorescence in serum, allowing for fast imaging in mice. Specifically, the sulfonate-carrying derivative enables clear video-rate imaging of vasculature with as little as 0.05 nmol injected dye, and the ammonium-modified dye shows strong retention in cells that enables tracking of xenograft tumor growth. We further showcase the versatility of this design by incorporating phosphonate functionalities for imaging of bone in awake and moving mice. This modular design of functional SWIR fluorophores in water provides insights for facile derivatization of existing fluorophores to introduce solubility and bioactivity towards bioimaging applications.
Anion Redox as a Means to Derive Layered Manganese Oxychalcogenides with Exotic Intergrowth Structures
Authors: Sasaki Shunsuke , Giri Souvik , Cassidy Simon , Dey Sunita , Batuk Maria , Vandemeulebroucke Daphne , Cibin Giannantonio , Smith Ronald I. , Holdship Phil , Grey Clare , Hadermann Joke , Clarke Simon
Published: November 2022

Topochemistry enables step-by-step conversions of solid-state materials often leading to metastable structures that retain initial structural motifs. Recent advances in this field revealed many examples where relatively bulky anionic constituents were actively involved in redox reactions during (de)intercalation processes. Such reactions are often accompanied by anion-anion bond formation, which heralds possibilities to design novel structure types disparate from known precursors, in a controlled manner. Here multistep conversion is presented of layered oxychalcogenides Sr2MnO2Cu1.5Ch2 (Ch = S, Se) into Cu-deintercalated phases where antifluorite type (Cu1.5Ch2)2.5- slabs collapsed into 2D arrays of chalcogen dimers. The collapse of the sulphide layers on deintercalation led to various stacking types of Sr2MnO2Ch2 slabs, which formed unprecedented polychalcogenide structures unattainable by conventional high-temperature syntheses. Anion-redox topochemistry is demonstrated to be of interest not only for electrochemical applications but also to design of complex novel layered architectures.
Simultaneous N-deglycosylation and digestion of complex samples on S-Traps enables efficient glycosite hypothesis generation
Authors: DeRosa Christine , Weaver Simon , Wang Chien-Wei , Schuster-Little Naviya , Whelan Rebecca
Published: November 2022

N-linked glycosylation is an important post-translational modification that is difficult to identify and quantify in traditional bottom-up proteomics experiments. Enzymatic deglycosylation of proteins by peptide:N-glycosidase F (PNGase F) prior to digestion and subsequent mass spectrometry analysis has been shown to improve coverage of various N-linked glycopeptides, but inclusion of this step may add up to a day to an already lengthy sample preparation process. An efficient way to integrate deglycosylation with bottom-up proteomics would be a valuable contribution to the glycoproteomics field. Here, we demonstrate a proteomics workflow in which deglycosylation and proteolytic digestion of samples occurs simultaneously using suspension trapping (S-Trap). This approach adds no additional time to standard digestion protocols. Applying this sample preparation strategy to a human serum sample, we demonstrate improved identification of potential N-glycosylated peptides in deglycosylated samples compared with non-deglycosylated samples, identifying 156 unique peptides that contain the N-glycosylation motif (Asparagine–X–Serine/Threonine), the deamidation modification characteristic of PNGase F, and an increase in peptide intensity over a control sample. We expect that this rapid sample preparation strategy will assist in the identification and quantification of both known and potential glycoproteins. Data are available via ProteomeXchange with identifier PXD037921.
Mediating Photochemical Reaction Rates at Lewis Acidic Lanthanides by Selective Energy Loss to 4f-Electron States
Authors: Ruoff Kevin , Gish Melissa , Song Ellen , Douair Iskander , Steger Mark , Johnson Justin , Carroll Patrick , Gau Michael , Chang Christopher , Larsen Ross , Ferguson Andrew , Schelter Eric
Published: November 2022

Manifesting chemical differences in individual rare earth (RE) element complexes is challenging due to the similar sizes of the tripositive cations and the core-like 4f-shell. We disclose a new strategy for differentiating between similarly-sized Dy3+ and Y3+ complexes through a tailored photochemical reaction, where the f-electron states of Dy3+ act as an energy sink. Complexes RE(hfac)3(NMMO)2 RE = Dy (2-Dy), Y (2-Y), hfac– = hexafluoroacetylacetonate, NMMO = N-methyl-morpholine-N-oxide, synthesized from their hydrated precursors, showed variable rates of oxygen atom-transfer to triphenylphosphine acceptor under UV irradiation, as monitored by 1H- and 19F-NMR spectroscopies. Ultrafast transient absorption spectroscopy identified the excited state(s) responsible for the photochemical OAT reaction. Sensitization pathways leading to excited state deactivation in 2-Dy through energy transfer to the 4f-electron manifold ultimately slow the reaction at that metal cation. The measured rate differences between the open- and closed-shell Dy3+ and Y3+ complexes demonstrates that using established principles of 4f-ion sensitization may deliver new, selective modalities for differentiating the elements that do not depend on cation size.
THE EFFECT OF JOB INSECURITY AND WORK STRESS ON WORK MOTIVATION ON BMT EMPLOYES IN THE REGENCY OF PURBALINGGA
Authors: Ulfa Nadia , Ario Wibowo Ugung Dwi , aeni Nur’ , dian Her
Published: November 2022

This study aims to determine the effect of job insecurity and stress on BMT employees’ work motivation in the Purbalingga Regency. The sample used in this study was 90 BMT employees in the Purbalingga Regency (43 men and 47 women, with an average age of 30 years). This research uses quantitative research methods. This study uses the job insecurity scale to measure the job insecurity scale, the work stress scale to measure the work stress scale, and the work motivation scale to measure the work motivation scale. The data analysis used is multiple linear regression analysis. The results of data analysis in this study obtained an F value of 1392,386 at a significance level of 5% with a p-value of 0.000 (P < 0.05), and an R-square determination of 0.970 was obtained. The coefficient of determinants shows that job insecurity and work stress effectively contribute 97% to work motivation, while 3% is influenced by other variables not examined in the study.
REVISITING THE STATUS OF AGRICULTURAL PRODUCTIVITY IN ODISHA
Authors: Pal Priti Plabani , Nayak Pragyan Parimita , Mallick Rajat Kumar
Published: November 2022

The present study analyses the productivity growth performance of major crop categories grown across the state of Odisha from 1970-71 to 2019-20. For analysing growth performance and comparing yield of important crops in Odisha, the research applies statistical methods such as annual growth rate (AGR), compound annual growth rate (CAGR), and ordinary least square method (OLS) of regression. On the other hand, the coefficient of variation (CV) and the instability index (Cuddy & Valle, 1978) have been used to investigate the state’s crop productivity instability. The study reveals the fact that the selected categories of crops which include cereals, oilseeds, pulses, food grains, fibres and small millets have not been experienced with steady annual growth rate from 1970-71 to 2019-20 rather they have been featured with high volatility. Moreover, the high degree of instability is evident in productivity of specified crop categories in Odisha. To boost agricultural production rates, it is vital to emphasise agricultural research and development and ensure that research discoveries are easily accessible to farmers, particularly small and marginal farmers. JEL Code: Q10, Q19
ARE COMPETENCIES OF AN ENTREPRENEUR DETERMINANT OF SUCCESS IN A CONFLICT ZONE: AN EVIDENCE FROM CONFLICT ZONE KASHMIR
Authors: Shah Mohd Shiob , Farooq Lala Muhammad
Published: November 2022

Exploring and understanding entrepreneurship in a conflict zone has been one of the concerns in entrepreneurship research. Responding to the concerns of multiple authors about providing empirical evidence from places under conflict, we present the findings relating entrepreneur and success in a conflict zone Kashmir. The study undertaken explores the impact of entrepreneurial competencies which include strategic, conceptual and commitment competencies on entrepreneurial success in a conflict zone. The findings of the current study reveal that competencies play a substantial role in achieving success in a conflict zone. Upon the analysis of data, we found that the hypothesized significant positive relationship of strategic, commitment and conceptual competencies with success was proven correct. Among the analyzed competencies, strategic competencies had the highest impact on success. Using Smart-PLS for analysis of data, we found that the theoretical model relating competencies and success was found to have a high predictive accuracy and relevance. The results of the study are expected to provide insights to the entrepreneurs, governments, and other stakeholders in a conflict zone. Especially, the institutions which impart entrepreneurship education and training in a conflict zone are provided with empirical evidence that competencies are an important asset for the successful entrepreneurial outcome. Because competencies are learnable, observable and therefore could be enhanced, as such special considerations should be given to entrepreneurial competencies.
CONFIRMATORY FACTOR ANALYSIS OF JOB SATISFACTION
Authors: Meilani Eka Rizki , Dwiyanti Retno
Published: November 2022

Every job creates satisfaction with the work done to get maximum results. This research aims to analyze the factors that influence job satisfaction, as well as find dimensions and indicators that can shape job satisfaction. Job satisfaction is measured by the dimensions of the work itself, salary, promotion, supervisor, and co-workers. The population in this research were junior high school teachers in Purwokerto, with a total of 327 teachers. The sample of this research was 90 teachers. The sampling technique in this research used accidental sampling. The data collection method is the job satisfaction scale. The research data were analyzed by Structural Equation Modeling (SEM) through SmartPLS program 3.2.8. The analysis results show that the dimensions and indicators that make up the job satisfaction construct are valid and reliable. The dominant dimension reflecting the construction of job satisfaction is co-workers, with a loading factor of 0.814. The lowest dimension reflecting the construct is the supervisor, with a loading factor of 0.766. Thus, all aspects and indicators can reflect and form a job satisfaction construct, as well as a measurement model that can be accepted because the theory that describes job satisfaction corresponds to empirical data obtained from the subject.
MULHERES NA DOCÊNCIA: NARRATIVAS E REFLEXÕES PARA A CONSTRUÇÃO DE UMA CONSCIÊNCIA CRÍTICA SOBRE SEXISMO, CULTURA E SOCIEDADE
Authors: Santos Luciana Xavier Morais dos , Gonçalez Mirian Maria Andrade
Published: November 2022

Este artigo parte dos resultados de uma pesquisa de mestrado que teve como objetivo investigar o movimento de formação continuada de professores que ensinam matemática, por meio de narrativas elaboradas segundo os parâmetros da História Oral. Nesse texto, apresentamos uma discussão sobre como os aspectos culturais atrelados à figura feminina influenciam nos processos formativos e, para isso, destacamos alguns trechos de narrativas em que as professoras compartilharam suas experiências a partir da participação na Oficina Pedagógica de Matemática (OPM), um projeto de extensão universitária, que tem como objetivo principal a elaboração e execução de oficinas pedagógicas de matemática, fundamentadas teórica e metodologicamente na teoria Histórico-Cultural e Teoria da Atividade. O objetivo desse texto é proporcionar reflexões que conduzam a um pensamento crítico sobre gênero, igualdade e desigualdade na profissionalização das mulheres que exercem a docência, discorrendo sobre aspectos históricos, culturais e sociais que as atravessam nesse percurso formativo e que ainda são latentes nas narrativas dessas professoras. Nesta perspectiva, propomos a discussão como uma forma de desconstruir barreiras que ainda prejudicam o acesso das professoras em espaços de formação científica e tecnológica, assim como, se constituem como limitadores do acesso à pesquisa e a qualidade dos processos formativos.
Formulation of sprouted cowpea yoghurt rich in antioxidant, as functional
drink for diabetics
Authors: Winarsi H. , Erminawati E. , Ramadhan G.R.
Published: November 2022

This study aimed to obtain a formula of Cowpea sprouted yoghurt (Cops-Yo) rich in
phenolic antioxidants, fibre, vitamin C, and protein based on Lactic Acids Bacteria (LAB)
levels and the proportion of sprouted cowpea milk (Cops-milk) and skim milk. This
factorial study used a completely randomized design (CRD), with a factor of LAB levels
and the proportion of sprouted cowpea milk and skim milk. Cops-Yo product was
obtained and tested for phenolic content (Folin Ciocialteau method), fibre (oven method),
vitamin C (Iodometry), and soluble protein (Lowry method). Data was tested using
ANOVA, followed by DMRT if there was significance at a 5% level. The best Cops-Yo
formula was obtained from a proportion of 70 parts of sprouted cowpea milk and 30 parts
of skim milk with 0.3% LAB. The product has characteristics that contain 529.75 mg
GAE/L of phenolic, 3.09% dietary fibre, 100.55 mg/100 g vitamin C, and 36.22% soluble
protein. The result reflects that Cops-Yo could help improve sugar levels in diabetic
patients.
Development of a Custom Extracorporeal Circuit for Endovascular Resuscitation Research
Authors: Abdou Hossam , Richmond Michael , Madurska Marta J , Elansary Noha , Morrison Jonathan J
Published: November 2022

Our aim was to demonstrate the utility and applicability of in vitro extracorporeal circuits in endovascular resuscitation research. The method for building an inexpensive in vitro extracorporeal circuit for endovascular resuscitation research is described. In this study, aortic cannulas and pump combinations were evaluated in the in vitro extracorporeal circuit. Then one aortic cannula and pump set up was evaluated in a post-mortem swine model. Flow data was collected and compared among groups. The peristaltic pump generated the highest flow as compared with the other pump combinations at any given catheter size. The peristaltic pump combined with the 10 Fr cannula produced the highest flow overall at 2,304 ml/min. This same combination produced a peak flow of 886 ml/min at the aortic root in the swine model. The flow generated in the swine model was less than half of that generated in the in vitro model. However, all flow was channeled through one outflow tract in the in vitro model whereas the swine aorta has several branches of outflow. As such, a 50% reduction in flow or greater is anticipated at the level of the aortic root. An in vitro extracorporeal circuit for endovascular research can be built for less than US$10,000, with most of the materials being reusable, and can be used to generate representative data that may be anticipated in a swine model.
Principios básicos y distinción entre cliente y parte interesada
Authors:   Florida State University, Tallahassee, Florida, US, Bailey Jon S. , Burch Mary R. ,   Tallahassee, Florida, US
Published: November 2022

Cuatro principios fundamentales, que todos los analistas de conducta deben esforzarse por encarnar, sirven de marco para el Código Ético para Analistas de Conducta. Los analistas de conducta deben utilizar estos principios para interpretar y aplicar las normas del código. Los cuatro principios fundamentales que deben guiar a los analistas de conducta son beneficiar a los demás; tratar a los demás con compasión, dignidad y respeto; comportarse con integridad y garantizar su propia competencia....
KAMPANYE AKI DAN AKB DI DINAS KESEHATAN KOTA PALOPO
Authors: Suriati Israini
Published: November 2022

Angka Kematian Ibu (AKI) di Indonesia masih tergolong sangat tinggi, ini jauh dari target pemerintah  Angka kematian ibu dan angka kematian bayi merupakan salah satu indikator tercapainya derajat Kesehatan di suatu negara. Dikarenakan AKI dan AKB menunjukkan kualitas dari pelayanan kesehatan yang didapatkan oleh masyarakat. Data dari dinas Kesehatan Provinsi Sulawesi Selatan, pada tahun 2021 lalu, dicatatkan total angka kematian ibu di Sulsel sebesar 195 kasus, sedang angka kematian bayi mencapai 844 kasus. Sedangkan data terbaru khusus di kota palopo selama memasuki Tahun 2022 terdapat 2 Ibu meninggal yang memiliki Riwayat komplikasi sebelumnya. Berdasarkan data Sampling Registration System (SRS) tahun 2018, sekitar 76% kematian ibu terjadi di fase persalinan dan pasca persalinan dengan proporsi 24% terjadi saat hamil, 36% saat persalinan dan 40% pasca persalinan. Yang mana lebih dari 62% Kematian Ibu dan Bayi terjadi di rumah sakit. Artinya akses masyarakat mencapai fasilitas pelayanan kesehatan rujukan sudah cukup baik. Kegiatan pengabdian ini di selenggarakan oleh Dinas Kesehatan Kota Palopo dengan mengundang kader sekota Palopo dan saya sendiri sebagai bidan praktisi yang mewakili untuk memberikan kampanye terkait dengan Angka Kesehatan Ibu dan Angka Kesehatan Bayi. Kegiatan ini di laksanakan pada tanggal 14 Juni 2022 di depan gedung Dinas Kesehatan Kota Palopo. Kegiatan ini dihadiri ibu kader sebanyak 200 orang sekota Palopo.
The Fundamental Causes of Economic Growth: A Comparative Analysis of the Total Factor Productivity Growth of European Agriculture, 1950-2005
Authors: Martín-Retortillo Miguel , Pinilla Vicente
Published: November 2022

In recent decades, the debate on economic growth has largely focused on the role of its fundamental causes: institutions, geography, trade, and culture. This study analyses the underlying causes of agricultural productivity growth in Europe during the second half of the twentieth century. To determine the importance of fundamental causes, Total Factor Productivity growth in European agriculture was calculated for the period 1950-2005 and several econometric models are discussed. This study highlights inclusive institutions, agricultural support policies that encourage innovation, qualified human capital and openness to international trade as key factors that favour productivity growth in agriculture.
Analisis Variasi Nilai Duty Cycle pada PWM Terhadap Durasi Pengisian Baterai Lithium-Ion dan Lithium-Polymer
Authors: Akbar Febriansyah Kumaraning , Rohman Fatkhur
Published: November 2022

Lithium batteries are currently widely used as energy storage devices in electric vehicles. However, it takes quite a long time to charge the battery. One solution to the problem of battery charging is to increase the charging voltage and current. The purpose of this study was to determine the effect of variation in the value of the duty cycle with pulse-width modulation on the duration of the battery charge. The battery charging test method uses various duty cycle values ranging from 50% to 100%. Data extraction uses a method of changing the output voltage and current with different duty cycle values on a pulse width modulation signal, which is controlled by the Arduino Uno microcontroller. The results of this study show that changes in the duty cycle value can affect the charging time of Lithium Ion and Lithium Polymer batteries. Fastest charging results on Lithium Ion battery 15,183 minutes with 100% duty cycle at 14V output voltage and 5.83A Lithium polymer battery 15,083 minutes with 100% duty cycle at 14V output voltage and current 6 ,14A.
Variasi Kadar CaCO3 Terhadap Pertumbuhan Fasa Suoperkonduktor BPSCCO-2223 Menggunakan Metode Pencampuran Basah
Authors: Wijaya Ketut Putra , Suprihatin Suprihatin , Manurung Posman
Published: November 2022

Telah dilakukan penelitian tentang pengaruh kadar CaCO3 terhadap pertumbuhan fasa BPSCCO-2223 menggunakan metode pencampuran basah dengan memvariasikan kadar Ca. Sintesis dilakukan dengan melarutkan sampel menggunakan HNO3 dan aquades secara perlahan kemudian dilakukan pengeringan pada suhu 300, 400, dan 600 ℃ secara bertahap. Sampel dikalsinasi selama 10 jam  pada suhu  800 ℃ dan disintering pada suhu 865℃ selama 10 jam. Hasil sintesis superkonduktor dikarakterisasi menggunakan XRD, SEM  dan uji Meissner. Hasil XRD menunjukkan  bahwa penambahan kadar Ca berpengaruh terhadap tingkat kemurnian fasa superkonduktor BPSCCO-2223. Pada penelitian ini, kadar Ca yang optimum yaitu Ca 2,05 mol dengan  nilai fraksi volume (Fv) sebesar 79,98%. Sedangkan fraksi volume terendah adalah Ca 1,95 mol sebesar 41,27%. Derajat orientasi yang relatif tinggi terdapat pada sampel Ca 2,10 mol sebesar 7,67% dan terendah terdapat pada Ca 1,95 mol sebesar 0%. Hasil SEM menunjukkan bahwa semua sampel telah memiliki lapisan-lapisan yang tersusun (terorientasi) dengan ruang kosong antara lempengan (void) relatif kecil. Hasil uji-Meissner menunjukkan bahwa Ca 2,05 mol mengalami efek Meissner lemah, sedangkan sampel BPSCCO-2223 yang lain tidak menunjukkan adanya efek Meissner dalam nitrogen cair    (77 K).Kata Kunci : BPSCCO-2223, Derajat Orientasi, Fraksi Volume, Superkonduktor, Uji-Meissner
Sistem Pendukung Keputusan Berbasis Web Rekomendasi Pekerjaan Bagi Lulusan JTI Polinema Dengan Metode SAW
Authors: Wibowo Dimas Wahyu , Mentari Mustika , Chandra Abdallah Darussalam , Kuddah Amin Anis , Putra Rahardhiyan Wahyu
Published: November 2022

Sistem Pendukung Keputusan adalah sebuah sistem yang mampu memberikan kemampuan pemecahan masalah maupun kemampuan pengkomunikasian untuk masalah dengan kondisi semi terstruktur dan tak terstruktur. Sistem rekomendasi tersebut memiliki hubungan dengan proses pengambilan keputusan. Pada penelitian ini, sistem pendukung keputusan akan digunakan untuk memilih lowongan pekerjaan yang sesuai dengan kriteria yang diinputkan user. Maka dibuatlah sistem pendukung keputusan ini yang menggunakan metode Simple Additive Weighting (SAW). Kriteria yang digunakan pada penelitian ini adalah pendidikan terakhir, IPK, usia, akreditasi, dan kemampuan berbahasa Inggris. Sedangkan untuk data alternatif, digunakan data lowongan kerja yang didapat dari situs-situs web penyedia informasi lowongan kerja. Untuk menggunakan sistem ini, user hanya perlu menginputkan kriteria-kriteria yang sesuai dengan user. Output dari sistem ini berupa daftar lowongan pekerjaan yang telah diurutkan berdasar bobot dari sistem Simple Additive Weighting (SAW). User juga dapat melihat informasi mengenai lowongan pekerjaan dengan lebih detail.Kata Kunci : Sistem, Rekomendasi, Lowongan, Pekerjaan, Simple additive
Desain Dan Analisis Pengaruh Parameter PI Pada Respon Sistem Kontrol Arus Purwarupa Kendaraan Listrik
Authors: Kurniawan Syah Hendri , Rohman Fatkhur
Published: November 2022

At this time, there are many electric vehicle manufacturers in Indonesia. The main obstacle in building electric vehicles is the electric motor control system, usually electric vehicles use the BLDC motor type. However, this type of motor has more complex control than conventional DC motors, it requires an encoder sensor to read the rotation of the motor with high accuracy, and a motor controller that can accurately control the amount of current in the motor. Based on the problem, the purpose of this study is to analyze the BLDC motor current control system using odrive motor driver and PI regulation, so that PI parameter values can be obtained to obtain a stable motor current control system, which can also produce system stability with small errors when the system is running. The results of the study show that variations in the value of the PI constant and the load affect the stability parameters of the system under steady-state error, rise time, and overshoot. At the same time, a change in the PI constant does not have a significant effect on the stability parameters of the system.
Sistem Informasi Geografis Pemetaan Museum Di Bali Berbasis Android
Authors: Renata Nyoman , Anggara Wijaya Nyoman Yudi , Kresna Sudiatmika Ida Bagus
Published: November 2022

A museum is an institution that maintains and exhibits a collection of objects of cultural and scientific value for research, educational and entertainment purposes. The purpose of the creation of the museum is a means of educational tourism, interesting and informative for society. Thus, the museum plays a very important role because the existence of the museum will provide a broad understanding for the community. But here the problem is the lack of comprehensive information about Bali's museums, especially museums that are rarely visited by tourists. So that people only know about famous museums. With this Android-based Bali Museum Map Information System, it can help both the public and tourists to find information about museums in Bali, ranging from well-known or frequently visited museums to rarely visited museums. The existence of this information system also helps to find information about the history of the museum, its location and the history of the existing collections in each museum. The method used in this study uses the prototype method, where every process that we have tested the user to what we are doing, met the user's expectations.
Rancang Bangun Pengendali Senjata SS1 Pemantau Keamanan Pos Perbatasan Berbasis Mikrokontroler
Authors: Apriyanto Rochmat , Rabi Abdul , Saputra Jeki , Mujahidin Irfan
Published: November 2022

The problem of borders between countries and between regions, both on land and at sea, is very complex. The current state of using security personnel at the border posts still has many limitations (human factor) in carrying out monitoring in the area of the border post. The guard post staff cannot fully carry out regional monitoring at the border post, as the visibility of each guard post staff member is still limited. As technology advances in the world, especially technology in the military, with the advent of upgrades in weapons control systems operating in automatic mode. This final design aims to develop the design or design of the SS1 weapons control system, which controls the security of border posts, automatically controls movements in azimuth and elevation. In this study, electronic control is used as an SS1 weapons control system to monitor the security of border posts. This tool is capable of moving 90˚ in azimuth and 15˚ in elevation to match the expected system of the tool.
Analisis Kesiapan Penerapan E-learning di Sekolah Dasar Menggunakan E-learning Readiness Model: Studi kasus Madrasah Islamiyah Darwata Karangasem
Authors: Arsyad Mirza Ali , Saintika Yudha , Setyadi Resad
Published: November 2022

In 2020, the world was shocked by the covid-19 virus, which has spread to all countries of the world, including Indonesia. In education, almost all schools in Indonesia have been forced to close by the government and replaced with distance learning. However, in many schools there are obstacles such as the inability of teachers and students to use technology. One of the problems in Islamiya Darwata Karangasem Madrasah. The purpose of this study was to determine the relationship between environmental, teacher, technology and student readiness and provide recommendations for schools to be more prepared to implement distance learning. The method used in this study is a descriptive analysis with an e-readiness model. The sample in this study consisted of 52 students and 9 teachers. The results showed that an overall ELR score of 3.62288 was included in the readiness category, but needed some improvement. The teacher had a score of 3.79167, which was classified as readiness, but needed some improvement. , which was included in 64814, is categorized as finished but needs work, and the technology is rated 3.48148, which means it's ready but needs a little improvement. By improving school internet speeds, evaluating student learning, providing new policies, changing individual perspectives, and increasing budgets.
Implementasi Pengamanan Sistem Informasi Personel Berbasis Website
Authors: Paramita Sari Resti Indah , Puspita Sari Anggraini , Yulisusianto Gatut
Published: November 2022

The SIP (Personnel Information System) is designed to assist staff in managing the personal data of STTAD on the website. This SIP is for personnel who need personal data quickly. In the STTAD environment, the current HR information system is still operated manually. Personnel who need personal data should contact the Administrative Personnel (TS) to obtain the data required by the personnel. Through XAMPP, PHP, MySQL and PHPMyAdmin will later be used as an environment for developing SIP websites that can be accessed on the Internet. SIP can display Curriculum Vitae (RH) data and dossiers according to employees who successfully logged in at that time. SIP can be accessed by users (users) online. As well as personal data that was entered by the administrator into the database and then registered in the domain house (domain name) so that he receives the domain address and the user can open it through a web browser. Which later this system can be visited by the user through a web browser and make it easier for staff in terms of searching for personal data of staff.
Image Extraction of Lettuce Leaves using Fast Fourier Transform Method and Color Moments
Authors: Erwanto Danang , Utomo Yudo Bismo
Published: November 2022

Lettuce (Lactuca sativa L.) is a seasonal leaf vegetable with high nutritional content which is usually fresh for consumption. Typical harvest age for lettuce is 45 days. Lettuce which is harvested more than 45 days will affect the taste of the lettuce. In addition to the lettuce’s age, there are several things that can affect taste of the lettuce, including room temperature, harvest time, and thickness of the leaf color. In this study, Fast Fourier transform (FFT) was used as feature extraction by changing the spatial domain in frequency domain image of the lettuce leaves, while the color moment method was used as the extraction of lettuce leaves. With this digital image processing, it can automatically identify maturity level of lettuce leaves. The classification process uses the Naïve Bayes method with the Weka application. The obtained results of texture and color extraction using FFT method and the color moment using Naïve Bayes classification method in the Weka application work well. From the results of the age classification of lettuce based on its leaf color, the average percentage of total accuracy was 94.4%. The correlation of color and taste using the correlation test which performed by SPSS, and it was found that there are positive relationship between color and taste with sig. (1-tailed) 0.05.
Inclusão e o Ensino de Ciências e Biologia Para Alunos com Transtorno do Espectro Autista: Análise dos Trabalhos Publicados nos Encontros Nacionais de Biologia e de Pesquisa em Educação em Ciências
Authors: Menezes Naiara Silva , Borges Dias Viviane
Published: November 2022

O presente trabalho analisou a produção científica sobre a inclusão de alunos com Transtorno do Espectro Autista (TEA) nos anais do Encontro Nacional de Ensino de Biologia (ENEBIO) e do Encontro Nacional de Pesquisa em Educação em Ciências (ENPEC), período de 2010 a 2020. A pesquisa tem abordagem qualitativa, do tipo levantamento bibliográfico, e foi realizada nos anais supracitados. Para selecionar os artigos, utilizamos os seguintes descritores: autismo, autista, Transtorno do Espectro Autista, inclusão, inclusiva, inclusivo. Ademais, fizemos uma busca a fim de comparar a produção de artigos que discutem a inclusão escolar de alunos com TEA com trabalhos que abordam outras deficiências, utilizando os descritores: deficiência visual, deficiência auditiva, surdo, cego, libras, cegueira ou surdez. A metodologia de análise de dados utilizada foi a análise de conteúdo descrita por Bardin (2016). Observamos uma baixa produção de trabalhos que relacionem ensino de Ciências, Biologia e TEA nos anais. A investigação revelou ainda que os trabalhos não apresentam um referencial teórico de base. Em relação ao referencial metodológico, a maioria dos trabalhos trata da abordagem qualitativa. Foi possível verificar ainda diversos aspectos clínicos como nomenclaturas e documentos médicos, a exemplo do laudo, como instrumentos balizadores da entrada/permanência do aluno na escola. Consideramos que pesquisas do tipo levantamento bibliográfico possibilitam um panorama dos estudos da área e colaboram com o desenvolvimento de futuras investigações que tenham como foco a inclusão dos alunos com TEA nas aulas de Ciências e Biologia.
Emoções e Museus de Ciência: Um Estudo com Visitas de Famílias ao Museu de Microbiologia do Instituto Butantan, São Paulo
Authors: Scalfi Graziele , Massarani Luisa , Gonçalves Waneicy , Marandino Martha
Published: November 2022

Os estudos em museus de ciência destacam cada vez mais o papel da emoção nas experiências de visita dos públicos. Neste artigo, nosso objetivo é investigar as características das experiências de emoções de famílias com crianças em visita ao Museu de Microbiologia do Instituto Butantan, São Paulo (Brasil). Participaram deste estudo três famílias, em um total de 10 pessoas, sendo quatro adultos (um homem e três mulheres) e seis crianças (três meninos e três meninas). Como instrumentos de coleta, utilizamos a observação das visitas familiares que foram gravadas por meio de uma câmera subjetiva e entrevistas realizadas com as crianças ao término do percurso. A análise de valência (sensação agradável ou desagradável experimentada) e excitação (se sentir ativo ou tranquilo) foi aplicada nas conversas e interações durante a visita e uma análise interpretativa das falas das crianças no processo de entrevista. De maneira geral, nossos resultados trazem evidências de que a experiência foi positiva e que a resposta emocional das famílias com crianças esteve relacionada ao interesse, à motivação, ao conhecimento e a experiências anteriores.
Respon Pertumbuhan Stek Batang Gamal (Gliricidia sepium) pada Berbagai Ukuran Bahan dan Pemberian Monosodium Glutamat (MSG)
Authors: Sukendro Andi , Dikari I Putu Wita Wardana Dharma
Published: November 2022

Gamal (Gliricidia sepium) is a plant that has many benefit in several aspect including ecology, economic and social. The purpose of the study was to obtain the respon of gamal cuttings to the administration of Monosodium Glutamate (MSG) and to obtain the best cuttings size. This research used a completely randomized design (CDR) with 2 factors, namely MSG and material size. The result showed that the interaction of MSG administration and differences in material size did not significantly affect each parameter tested. The treatment of MSG alone also had no effect, while treatment of differences in the size of the material significantly affected the parameters of shoot length and root length. Gamal stem cuttings has the best growth using 70 cm long material.

Keywords: Gliricidia sepium, material size, MSG, stem cuttings
Komposisi Struktur dan Penyebaran Bidara (Ziziphus mauritiana Lamk.) pada Savana Bekol Taman Nasional Baluran
Authors: Istomo Istomo , Utami Ariyani Pramudita
Published: November 2022

Savanna is the icon of Baluran National Park. The endemic species of Bekol Savana is bekol or bidara (Ziziphus mauritiana Lamk.). Emerge complication instant exotic like Acacia nilotica spread in Savanna for nature fire burning partition plant. Growth of A. nilotica is invasive so can be change nature conditition of savanna. The goals are to know composition structure and pattern distribution of Z. mauritiana in raise savanna and invasive savanna. Examination did with rectangular plot of analisis vegetation as purposive sampling in wide 20 m x 60 m in 10 plot each location. The result shows the structure in raise savanna is opened area and have density of grass is abundant than density tree is low and the invasive savanna is change to be closed A. nilotica forest. Density of Z. mauritiana in raise savanna is more which 3 364/ind/ha than invasive savanna is 260 ind/ha. Pattern distribution of Z. mauritiana in Bekol Savanna is clumped. Biofisic factors can be straddling of Z. mauritiana are open area, clay loam teksture, alkaline pH and arid season.

Keywords: Bekol Savanna in Baluran National Park, Bidara (Z. mauritiana), pattern distribution, structure
Potensi Kebakaran Hutan BKPH Dander, KPH Bojonegoro, Jawa Timur
Authors: Saharjo Bambang Hero , Wintanti Rizkia Ajeng Setya
Published: November 2022

The potential of forest fires in BKPH Dander KPH Bojonegoro can be assessed based on forest fires sourse, the control efforts, and rainfall. This study aims to analyze the source of forest fires and the control efforts done by BKPH Dander, and analyze the level of vulnerability of forest fires based on rainfall. The data used is divided into primary data and secondary data. Average annual rainfall in last 5 years is 1 788.8 mm/years with total area of forest fires 44.66 Ha and total loss approximately Rp5.645.300. The potential of forest fires based on land clearing in BKPH Dander are medium, meanwhile the potential by conflict caused of the burning activity by some perpetrator with their own circumstances and for thair needs. Optimalization the control effort of forest fires showing good result, it caused by the cooperation of community's high awarness and participation to protect and sustaining forest environment.

Keywords: Community participation, Forest fire, KPH Bojonegoro, prevention, potency.
Peran Masyarakat dalam Pengendalian Kebakaran Hutan di KPH Cepu, Jawa Tengah
Authors: Saharjo Bambang Hero , Artaningsih Indah
Published: November 2022

Forest Fire is one form of forest destruction. The cause of forest fires is usually due to the clearing of forest areas used for agricultural land. There are 2 factors for forest fires namely natural and human factors. Natural factors are caused by volcanic and lightning eruptions, then human factors due to the clearing of forest areas for agricultural areas. This study aims to examine the efforts and role of the community in controlling forest fires at KPH Cepu, Central Java. The highest incidence of forest fires occurred in 2015 with a frequency of 40 times with a total area of land that burned 140.0 Ha. Forest fires in 2015 were the largest forest fires in the Cepu KPH, costing Rp38.292.909. The form of control carried out by the KPH Cepu itself is through counseling or socialization related to fire and how to deal with it in the event of a fire. The form of direct counseling is given to the LMDH community association, RT association, and other unspecified associations. Community participation is very high in prevention and blackout activities at KPH Cepu, Central Java.

Keywords: Factors, participation, control of forest fires
PENGARUH PENYULUHAN ONLINE TERHADAP PERUBAHAN PENGETAHUAN DAN SIKAP SISWA SMK NEGERI 1 KOTA BIMA MENGENAI TINDAKAN ABORSI PADA TAHUN AJARAN 2020
Authors: Anisa  , Syamsun Arfi , Jumsa Muhammad Rizkinov
Published: November 2022

Latar Belakang: Kurangnya pengetahuan tentang waktu yang aman untuk melakukan hubungan seksual dapat mengakibatkan terjadinya kehamilan, yang sebagian besar tidak dikehendaki. Kehamilan menimbulkan situasi yang serba salah dan memberikan tekanan batin (stress), oleh karena itu untuk menghentikan kehamilan dilakukan tindakan aborsi. Aborsi adalah pengeluaran hasil konsepsi sebelum janin dapat hidup diluar kandungan.

Tujuan: Untuk mengetahui pengaruh penyuluhan terhadap perubahan pengetahuan dan sikap siswa SMK Negeri 1 Kota Bima mengenai tindakan aborsi pada tahun ajaran 2020.

Metode: Penelitian ini bersifat analitik pre-eksperimental dengan desain one group pretest-posttest. Lokasi penelitian di SMK Negeri 1 Kota Bima. Penelitian dilakukan bulan September-Oktober 2020 dengan jumlah sampel 36 siswa kelas XI jurusan Kriya Batik dan Tekstil. Sampel diambil dengan cara total sampling. Analisis data dengan menggunakan uji statistik wilcoxon.

Hasil: Pengetahuan sebelum penyuluhan berada dalam kategori cukup sebanyak 22 orang (61,1%) dan setelah dilakukan penyuluhan berubah menjadi kategori baik sebanyak 27 orang (75,0%). Sikap siswa sebelum penyuluhan menunjukkan sikap positif yaitu tidak setuju terhadap tindakan aborsi sebanyak 33 orang (91,7%) dan setelah diberikan penyuluhan sikap siswa berubah menjadi 100% tidak setuju. Hasil uji wilcoxon variabel pengetahuan dan sikap setelah dilakukan pretest-posttest menunjukkan nilai signifikansi untuk variabel pengetahuan sebesar 0,000 yang berarti lebih kecil dari nilai ?=0,05 menandakan terdapat perubahan secara signifikan berdasarkan statistic teruntuk variabel pengetahuan. Sedangkan, nilai signifikan untuk variabel sikap setelah dilakukan pretest-posttest menunjukan hasil sebesar 0,083 yang menandakan lebih besar dari nilai ?=0,05 sehingga tidak terdapat perubahan secara signifikan berdasarkan statistik.

Kata kunci : Penyuluhan, Tingkat Pengetahuan, Sikap, Tindakan Aborsi
PEPTIDE RECEPTOR RADIONUCLIDE THERAPY
Authors: Hidayatullah Rian , Budiawan Hendra , Darmawan Budi , Affandi Erwin
Published: November 2022

Peptide receptor radionuclide therapy (PRRT) is an effective and usually well-tolerated treatment for unresectable or metastatic neuroendocrine tumors expressing somatostatin receptors. Somatostatin analog which is labeled by ?- or ?-emitting radionuclide binds specifically to SSTRs abnormally expressed in NETs. The two radiopharmaceuticals most commonly used for PRRT are 90Y-DOTATOC and 177Lu-DOTATATE which have been demonstrated to provide an effective tumor response and symptom relief with positive impact on survival. Chronic side effects on the kidneys and bone marrow are generally mild. The radiopharmaceuticals is internalized into the cell for the irradiation. Furthermore, the long half-life of the analog maintains a persistent therapeutic effect. Different approaches are now under evaluation to improve PRRT efficacy, it may be expected that the use of PRRT will increase in the coming years.
GAMBARAN PERESEPAN OBAT TRADISIONAL DI POLI JAMU PUSKESMAS PEJERUK AMPENAN KOTA MATARAM PERIODE JULI-DESEMBER 2017
Authors: Permatasari Kartika , Aini Siti Rahmatul , Hanifa Nisa Isneni
Published: November 2022

Obat diresepkan oleh dokter dengan mempertimbangkan beberapa aspek yaitu pembuktian obat secara ilmiah, obat yang paling bermanfaat, paling aman dan paling ekonomis. Obat tradisional merupakan salah satu obat yang dapat digunakan oleh dokter dalam terapi karena memiliki efek samping yang sedikit dan aman digunakan. Ramuan B2P2TOOT (Balai Besar Penelitian dan Pengembangan Tanaman Obat dan Obat Tradisional) merupakan salah satu obat tradisional yang memiliki peresepan tertinggi di 12 provinsi. Penelitian ini bertujuan untuk mengetahui gambaran peresepan obat tradisional di Puskesmas Pejeruk Ampenan yang memberikan pelayanan poli Jamu (Ramuan B2P2TOOT). Penelitian ini bersifat deskriptif retrospektif, data yang diperoleh diolah menggunakan Microsoft excel. Hasil yang diperoleh, penyakit yang dominan diresepkan obat tradisional adalah penyakit degeneratif (kolesterol, hipertensi, asam urat dan diabetes melitus) dengan peresepan obat yang lebih dominan oleh dokter yaitu 2x2 caps/hari dengan jumlah obat yang diresepkan sebanyak 40 kapsul dengan lama terapi 10 hari.