bluuebunny/crossref_metadata_2025 huggingface dataset:
The Possible Role of Pathogenic and Non-Pathogenic Bacteria in Initiation and Exacerbation of Celiac Disease; A Comprehensive Review
Authors: Azimi Taher , Nasser Ahmad , Shariati Aref , Shiadeh Seyedeh M.J. , Safari Hossein , Alizade-Sani Mahmood , Taghipour Ali , Dehghan Amin
Published: December 2019

Celiac Disease (CD) is an immune-mediated enteropathy, generally of the proximal intestine, that occurs in genetically susceptible individuals triggered by the ingestion of gluten. The incidence and frequency of CD are increasing, and it is predicted that CD affects approximately 1% of the people worldwide. The common clinical manifestations of CD are divided in two sections, including classic and non-classic symptoms that can be created in childhood and adulthood. The relationship between pathogenic and non-pathogenic bacteria with CD is complex and multidirectional. In previous published studies, results demonstrated the triggering impact of bacteria, viruses, and parasites on initiation and development of Inflammatory Bowel Disease (IBD) and Irritable Bowel Syndrome (IBS). Different studies revealed the inducing effect of pathogenic and non-pathogenic bacteria on CD. However, increasing evidence proposes that some of these microorganisms can also play several positive roles in CD process. Although information of the pathogenesis of the CD is quickly expanding, the possible role of bacteria needs further examination. In conclusion, with respect to the possible correlation between different bacteria in CD, the current review-based study aims to discuss the possible relationship between CD and pathogenic and non-pathogenic bacteria and to show various and significant aspects of mechanisms involved in the CD process.
Recent Advancements in Biological Activities of Oxadiazole and their Derivatives: A Review
Authors: Mishra Arun Kumar , Kumar Arvind , Sahu Jagdish K.
Published: December 2019

Oxadiazole moiety, which is one of the heterocyclic aromatic groups of the azole family; with the molecular formula C2H2N2O, exists in four isomeric form; out of which, 1,2,4-oxadiazole; 1,2,5-oxadiazole and 1,3,4-oxadiazole are common isomers. The stable isomeric forms of oxadiazoles are observed in a variety of pharmaceutical important potent drugs including raltegravir, butalamine, fasiplon, oxolamine and pleconaril. An attempt has been made to emphasize the chemistry and pharmacology associated with oxadiazole and its derivatives. A number of oxadiazole derivatives are very popular and common in use as potential therapeutic agents. However, a number of researchers are working and have worked to find out more synthetic analogues for anticancer and antifungal, anti-HIV agents using biological and in-silico models.
Chiral Catalysts Utilized in the Nucleophilic Addition of Dialkyl-zinc Reagents to Carbonyl Compounds
Authors: Cetin Adnan
Published: December 2019

The aim of this review is an overview of diverse dialkyl zinc pro-chiral aldehydes addition
reactions. One way of conducting asymmetric reactions is through the use of chiral catalyst. Therefore,
new chiral ligands have attracted considerable attention in organic chemistry. Carbon-carbon bond
formation reactions are an active research topic. The addition of dialkyl zinc to pro-chiral aldehydes is
one of these popular reactions. Also, the chiral amino alcohols are important substrates for drug
synthesis. These chiral ligands can be prepared by a simple synthetic way from easily accessible
starting materials. This article reviews current catalyst reactions with the addition of dialkyl zinc to
carbonyl compounds.
Cardiac Amyloid - A Hidden Contributor to Cardiac Dysfunction Following Cardiac Surgery: Case Report and Literature Review
Authors: Flood Trevor A. , Bradshaw Scott H. , Veinot John P. , Nair Vidhya
Published: December 2019

We present two patients who underwent cardiac surgery followed by post-operative low
cardiac output, diastolic dysfunction and resistance to inotropic support. Despite aggressive medical
management, both patients died. At autopsy, the hearts were enlarged and showed previously undiagnosed
myocardial and vascular amyloidosis. Occult cardiac amyloidosis is an uncommon, often
occult, contributor to post-operative complications post cardiac surgery. Pre-operative or intraoperative
myocardial biopsy may be useful in patients with unexplained diastolic dysfunction.

Brief Summary:

We present two patients who underwent cardiac surgery followed by low cardiac
output, diastolic dysfunction and resistance to inotropic support. Cardiac dysfunction was due to
occult amyloidosis. Pre-operative or intra-operative myocardial biopsy may be useful in patients
with unexplained diastolic dysfunction. With recent therapy advances, classification and possible
treatment of amyloid are possible.
The Anticancer Properties of Silibinin: Its Molecular Mechanism and Therapeutic Effect in Breast Cancer
Authors: Binienda Agata , Ziolkowska Sylwia , Pluciennik Elzbieta
Published: December 2019

Background:

Silibinin (SB), the main component of Silymarin (SM), is a natural substance obtained
from the seeds of the milk thistle. SM contains up to 70% of SB as two isoforms: A and B. It has an antioxidant
and anti-inflammatory effect on hepatocytes and is known to inhibit cell proliferation, induce apoptosis, and
curb angiogenesis. SB has demonstrated activity against many cancers, such as skin, liver, lung, bladder, and
breast carcinomas.

Methods:

his review presents current knowledge of the use of SM in breast cancer, this being one of the most
common types of cancer in women. It describes selected molecular mechanisms of the action of SM; for example,
although SB influences both Estrogen Receptors (ER), α and β, it has opposite effects on the two. Its action on ERα
influences the PI3K/AKT/mTOR and RAS/ERK signaling pathways, while by up-regulating ERβ, it increases
the numbers of apoptotic cells. In addition, ERα is involved in SB-induced autophagy, while ERβ is not. Interestingly,
SB also inhibits metastasis by suppressing TGF-β2 expression, thus suppressing Epithelial to Mesenchymal
Transition (EMT). It also influences migration and invasive potential via the Jak2/STAT3 pathway.

Results:

SB may be a promising enhancement of BC treatment: when combined with chemotherapeutic drugs
such as carboplatin, cisplatin, and doxorubicin, the combination exerts a synergistic effect against cancer cells.
This may be of value when treating aggressive types of mammary carcinoma.

Conclusion:

Summarizing, SB inhibits proliferation, induces apoptosis, and restrains metastasis via several mechanisms.
It is possible to combine SB with different anticancer drugs, an approach that represents a promising therapeutic
strategy for patients suffering from BC.
Pharmacokinetics and Acute Toxicity of a Histone Deacetylase Inhibitor, Scriptaid, and its Neuroprotective Effects in Mice After Intracranial Hemorrhage
Authors: Yang Heng , Gao Xinjie , Su Jiabin , Jiang Hanqiang , Lei Yu , Ni Wei , Gu Yuxiang
Published: December 2019

Background & Objective:

The pharmacokinetics and acute toxicity of a histone deacetylase
inhibitor, Scriptaid, was unknown in the mouse. The aim of this study was to determine the pharmacokinetics,
acute toxicity, and tissue distribution of Scriptaid, a new histone deacetylase inhibitor, in
mice, and its neuroprotective efficacy in a mouse intracranial hemorrhage (ICH) model.

Methods:

The pharmacokinetics, acute toxicity, and tissue distribution were determined in C57BL/6
male and female mice after the intraperitoneal administration of a single dose. Behavioral tests, as well
as investigations of brain atrophy and white matter injury, were used to evaluate the neuroprotective
effect of Scriptaid after ICH. Western blotting was used to investigate if Scriptaid could offer antiinflammatory
benefits after ICH.

Results:

No significant differences were observed in body weight or brain histopathology between the
group that received Scriptaid at 50 mg/kg and the group that received dimethyl sulfoxide (control).
The pharmacokinetics of Scriptaid in mice was nonlinear, and it was cleared rapidly at low doses and
slowly at higher doses. Consistent with the pharmacokinetic data, Scriptaid was found to distribute in
several tissues, including the spleen and kidneys. In the ICH model, we found that Scriptaid could reduce
neurological deficits, brain atrophy, and white matter injury in a dose-dependent manner. Western
blotting results demonstrated that Scriptaid could decrease the expression of pro-inflammatory cytokines
IL1β and TNFα, as well as iNOS, after ICH.

Conclusion:

These findings indicate that Scriptaid is safe and can alleviate brain injury after ICH,
thereby providing a foundation for the pharmacological action of Scriptaid in the treatment of brain
injury after ICH.
Mean Platelet Volume and Red Cell Distribution Width in Differentiated Thyroid Cancer Patients
Authors: Ozmen Hilal Kiziltunc , Askin Seda , Simsek Eda , Carlioglu Ayse , Arikan Şenay , Utlu Mustafa
Published: December 2019

Aim:

The purpose of this study was to investigate MPV and RDW values in DTC patients.

Background:

Differentiated Thyroid Cancer (DTC) is subdivided into papillary, follicular and papillary micro thyroid cancers. Mean Platelet Volume (MPV) and red cell distribution width (RDW) are markers which have been investigated in many cancers, but no data are available for DTC.

Objective:

MPV and RDW values were assessed in 108 patients with DTC, consisting of 44 with Papillary Thyroid Cancer (PTC) (mean age 43±13.9 years), 34 with Papillary Micro Thyroid Cancer (PmTC) (mean age 43.1 ± 10.6), and 28 with Follicular Cancer (FC) (mean age 46.9±12.5), and 77 control subjects (mean age 47.5±5.9).

Methods:

The patient and control groups were matched in terms of age, and body mass index. All subjects were investigated using platelet and biochemical parameters.

Results:

Both MPV [(PTC, PmTC, and FC) (p=0.000, p=0.000 and p=0.001, respectively)] and RDW (PTC, PmTC, and FC) (p=0.02, p=0.04 and p=0.02, respectively)] values increased in patients with DTC compared to the controls. MPV values were significantly positively correlated with CRP (r=0.247; p=0.043), postoperative thyroglobulin (r=0.246; p=0.03), gamma glutamyl transferase (r=0.024; p=0.762), tumor size (r=0.209; p=0.047) and RDW (r=0.207; p=0.005). Age, gender, total cholesterol, and C-reactive protein were identified as independent predictors of MPV. Adjustment for other these factors produced no alteration in these relative risks at multiple regression analysis.

Conclusion:

Our results suggest that patients with DTC have higher MPV and RDW values than healthy controls. MPV may represent a good follow-up criterion in DTC patients because of its positive correlation with tumor size and thyroglobulin.
Questioning Global Citizenship Education in the Internationalization Agenda
Authors: Freire Oliveira Piccin Gabriela , Finardi Kyria Rebeca
Published: December 2019

The present paper provides a reflection on global citizenship education (GCE) in the internationalization agenda. With that aim, the internationalization of higher education (IHE) is discussed from a critical perspective, mainly informed by postcolonial and decolonial studies. More specifically, the paper addresses GCE issues related to criticisms that have been raised against it in terms of (1) its different educational approaches, (2) its cosmopolitan bias with its (3) ideological frame of the so-called “global citizen”. Some alternatives to mainstream approaches to GCE and IHE are offered in the conclusion, based on the contributions of Stein (2017), Andreotti (2015) and Fiedler (2007), who advocate for the otherwise approach and/or postcolonial learning spaces.
Vietnamese Consortium Fellowship
Authors: Tan Poh
Published: December 2019

On August 7, 2019, Dr. Allan Mackinnon and the Faculty of Education welcomed back five Vietnamese Consortium Fellowship Program alumni and their spouses to share discussions on how the program impacted and influenced their role as a teacher in Vietnam.
Quando o corpo se torna rosto
Authors: Marques Bruno
Published: December 2019

Que espaço ocupa o retrato num panorama que dá tanta ênfase ao corpo? É caso para dizer que o corpo, a partir das últimas décadas do século XX, se tornou num significante despótico que subordina qualquer expressão artística chegando mesmo ao ponto de afectar a prática do retrato ousando eclipsar daquilo que com ele estava mais conotado: a imagem de um rosto. Partindo do conceito de visagéité de Gilles Deleuze e Félix Guattari e das noções “paisagens-corpos”, “paisagens-rostos” e “devir-rosto” desenvolvidas por José Gil, predentemos com este ensaio reflectir sobre um processo que aqui designamos de “transferência de funcionalidade”, através da qual o corpo se torna “rosto”.
O Blocódromo está na rua: a apropriação mercadológica e os blocos de carnaval da cidade do Rio de Janeiro
Authors: Ribeiro Tiago Luiz Dos Santos , Ferreira Felipe
Published: December 2019

A partir da proposta da Prefeitura da Cidade do Rio de Janeiro de criar uma arena para desfile de blocos carnavalescos, para o carnaval de 2018, projeto que ficou conhecido como “Blocódromo”, visamos identificar que aspectos deste empreendimento – que não saiu do papel – ganharam vida no carnaval de 2019. Para tanto, abordaremos esta manifestação carnavalesca como objeto de ressignificações na sociedade contemporânea, o que se revela de modo evidente nos variados estágios de reformulação do projeto Arena Carnaval Rio, tanto em 2018 (o que inclui mudanças estruturais e de data) como em 2019, quando recebeu um outro formato, cuja implementação esbarrou em novos processos de negociação. A partir daí, utilizando alguns blocos de carnaval, analisaremos a ideia de apropriação destes grupos como produtos de interesse mercadológico, tanto por empresas privadas quanto pelo poder público, destacando questões como a perda de controle sobre práticas culturais assim como os efeitos da mercantilização e turistificação do carnaval carioca. Através das tensões e diálogos entre os diversos atores envolvidos observaremos como este tipo de organização carnavalesca desafia o projeto de ordenação da festa, por meio das disputas de poder nas vias públicas, enquanto se revela uma atraente fonte de receita.
Recensie van: Zij komen allen aan de beurt, de Zwarten: Het kamp van Lokeren 1944-1947 / Björn Rzoska (1999)
Authors: Wils Lode
Published: December 2019

recensie
Фотодиэлектрический эффект в кристаллах силленита Bi-=SUB=-12-=/SUB=-SiO-=SUB=-20-=/SUB=-
Authors: Аванесян В.Т. , Писковатскова И.В.
Published: December 2019

Abstract The results of studies of the effect of illumination on the frequency dependence of the electrical parameters of bismuth silicate Bi_12SiO_20 single crystals are presented. Illumination in the visible spectral region induces a change in the dielectric parameters (the photodielectric effect) and the manifestation of photoconductivity in the low-frequency region under study. The hopping character of conduction in the dark and upon excitation with light is established. The possible mechanisms of the photodielectric effect and charge transport in the crystals are discussed.
Аномальное краевое свечение ZnSe, сильно легированного кислородом
Authors: Морозова Н.К. , Мирошникова И.Н.
Published: December 2019

The features of the emission spectra of high-purity CVD ZnSe condensates grown with excess selenium and strong oxygen doping were studied. Investigated prevalent in the spectra of low-temperature cathodoluminescence of ZnSe∙O abnormal edge emission 477-490 nm to ascertain its nature. The connection of this luminescence with the stoichiometric composition of ZnSe and the concentration of dissolved oxygen is established.Obtained data indicating the role admixture of copper. Based on the theory of anti-crossing zones, a band model is presented, explaining the nature of the main luminescence bands of ZnSe∙O in the near edge region of the spectrum. It is shown that the model is identical for ZnSe, ZnS and CdS.
Неодномерный эффект dU/dt в мощных тиристорах
Authors: Юрков С.Н. , Мнацаканов Т.Т. , Тандоев А.Г.
Published: December 2019

The method allowing to take into account the influence of the design peculiarities of a power thyristor on its dU/dt parameter is described. A simple model is proposed, that makes it possible to find the parameters of the auxiliary thyristor structure that belongs to the regenera-tive control gate and provides the given value of the thyristor dU/dt parameter. The minimum possible value of turn-on current of the thyristor, limited by a given value of the maximum rate of voltage rise, is found.
Cиловой МДП-транзистор на 4H-SiC с эпитаксиальным заглубленным каналом
Authors: Михайлов А.И. , Афанасьев А.В. , Ильин В.А. , Лучинин В.В. , Решанов С.А. , Schoner A.
Published: December 2019

Abstract A method for reducing the on-state resistance of a high-power 4 H -SiC metal-oxide-semiconductor field-effect transistor (MOSFET) by forming a buried channel via the growth of epitaxial layers on the surface of the heavily doped p -region is proposed. The features of the carrier transport in the epitaxial buried channel are considered in comparison with that fabricated by conventional technology. A more than threefold decrease in the resistance of the high-power MOSFET is achieved.
Неравновесная кинетика начальной стадии фазового перехода
Authors: Змиевская Г.И.
Published: December 2019

Kinetic partial differential equations of Kolmogorov-Feller and Einstein-Smoluchowski equation with nonlinear coefficients are solved by a new, stable numerical methods. The theory of stochastic dynamic variables establishes the connection of the solution of Ito stochastic equations in the sense of Stratonovich for the trajectories of Wiener random processes with the transition probability density of these processes, or distribution functions of kinetic equations. The classical theory of nucleation (formation of nuclei of the first order phase transition) describes a non-equilibrium stage of the condensation process by a diffusion random process in the space of the size of the nuclei of the phase transition, when fluctuations affect the clustering of the nuclei. The model of formation of vacancy-gas defects (pores, blisters) in the crystal lattice, arising as a result of its irradiation by inert gas ions xenon, is supplemented by the consideration of Brownian motion of non-point lattice defects, occurring under the action of superposition of paired long-range potentials of indirect elastic interaction of pores between themselves and with the boundaries of the layers. Pores coordinates are changing at times of the order of 10 − 100 ms, sustainable algorithms for calculating which provide a self-consistent defnition spatial - temporal structures of porosity in the sample. According to calculations of 106 trajectories, non-equilibrium kinetic functions were found. Pores distribution in size and coordinates in the layers of the irradiated materials, they characterize the fluctuation instability the initial stage of the phase transition, they are estimated local stresses and porosity in the model volume.
Синхротронные, рентгеновские и электронно-микроскопические исследования каталитических систем на основе многостенных углеродных нанотрубок, модифицированных наночастицами меди
Authors: Сивков В.Н. , Объедков А.М. , Петрова О.В. , Некипелов С.В. , Мингалева А.Е. , Кремлев К.В. , Каверин Б.С. , Семенов Н.М. , Кадомцева А.В. , Гусев С.А. , Юнин П.А. , Татарский Д.А.
Published: December 2019

Abstract The results of the studies of a composite based on multiwalled carbon nanotubes (MWCNTs), onto the outer surface of which nanosized copper particles are deposited by the pyrolysis of copper formate, via electron microscopy, X-ray diffractometry, and ultrasoft X-ray spectroscopy, are discussed. It is found that, in an inert argon atmosphere, copper nanoparticles are deposited onto the surface of MWCNTs in the form of different-size nanoparticles consisting of a metallic copper nucleus and a cuprous oxide Cu_2O shell. However, after being taken out into the atmosphere, a layer of copper oxide CuO is formed on the surface of the copper nanoparticles. It is shown that the good adhesion of the copper nanoparticles on the surface of the MWCNTs is provided by the formation of a chemical bond between the carbon atoms of the outer graphene layer of the nanotube and the oxygen atoms of cuprous oxide Cu_2O that initially covers the metallic nucleus of the nanoparticles.
Механизмы переноса тепла и температурная зависимость теплового сопротивления кристаллов CaLa-=SUB=-2-=/SUB=-S-=SUB=-4-=/SUB=-
Authors: Лугуев С.М. , Лугуева Н.В. , Лугуев Т.С.
Published: December 2019

The results of the study of the temperature dependence of the thermal resistance of CaLa2S4 crystals in the temperature range of 80–450 K according to the measurement of their thermal conductivity are presented. The mechanisms of heat transfer in samples with different technological background are established. The causes that determine the magnitude and characteristics of the temperature dependence of the thermal resistance of CaLa2S4 crystals in the region and above the Debye temperature are revealed.
Моделирование диффузии ускоренных частиц в бесстолкновительных ударных волнах с примесью ионов тяжелее водорода
Authors: Кропотина Ю.А. , Быков А.М. , Осипов С.М. , Ермолина В.Е. , Романский В.И.
Published: December 2019

Представлены результаты гибридного моделирования диффузионного ускорения ионов с различным соотношением заряда к массе в квазипродольных бесстолкновительных ударных волнах. Рассмотрена водородная среда с динамически незначимой примесью ионов гелия и углерода в различных зарядовых состояниях. Определены пространственные области применимости бомовского приближения, а также квазилинейной теории диффузии. Обсуждается возможность недиффузионного распространения в областях далеко перед фронтом ударной волны. Ключевые слова: диффузия, бесстолкновительные ударные волны, космические лучи, квазилинейная теория.
Модификация свойств поверхности свободных пленок Si-Cu имплантацией ионов активных металлов
Authors: Исаханов З.А. , Косимов И.О. , Умирзаков Б.Э. , Ёркулов Р.М.
Published: December 2019

Методами оже-электронной спектроскопии, спектроскопии характеристических потерь энергии электронами и ультрафиолетовой фотоэлектронной спектроскопии изучено влияние имплантации ионов Ва+ на состав, кристаллическую и электронную структуры поверхности свободных пленок Si-Cu(100). В частности, показано, что имплантация ионов Ва и последующий отжиг позволяют получить нанопленки типа ВаSi с некоторым (до 10 at.%) избытком несвязанных атомов Si. Ключевые слова: оже-электронная спектроскопия, имплантации ионов Ва+, нанопленки.
Пробеги атомов водорода, дейтерия, гелия в аморфных кремнии и вольфраме
Authors: Мелузова Д.С. , Бабенко П.Ю. , Шергин А.П. , Зиновьев А.Н.
Published: December 2019

Получены распределения пробегов для атомов H, D, He с энергиями в диапазоне 0.1-100 keV в аморфных W и Si для нормального падения налетающих частиц. Расчеты проведены как в приближении парных соударений, так и более точным методом расчета траекторий частиц. Показано, что результаты обоих методов хорошо согласуются между собой и с экспериментальными данными по средним пробегам для системы H-Si. Оценено влияние притягивающей ямы в потенциале взаимодействия налетающей частицы с атомами твердого тела на результаты расчетов. Ключевые слова: пробеги, вольфрам, кремний, аморфный.
Линейная трансформация поляризационных мод в намотанных на катушку spun-световодах. III. Приближенное аналитическое представление
Authors: Малыкин Г.Б. , Позднякова В.И.
Published: December 2019

С использованием аппроксимации проведенного численного моделирования получены приближенные аналитические зависимости интегральных величин эффективного эллиптического двулучепреломления собственных поляризационных мод от длины намотанных на катушку spun-световодов. Показано, что зависимость интегрального эллиптического двулучепреломления собственных поляризационных мод от длины этих световодов весьма быстро выходит на свое предельное значение. Показано также, что зависимость интегральной эллиптичности собственных поляризационных мод намотанных на катушку spun-световодов от их длины имеет сложную периодическую структуру, включающую два существенно различных пространственных периода. Вид рассматриваемых зависимостей определяется длинами поляризационных биений невозмущенного намоткой исходного линейного двулучепреломления spun-световода и циркулярного двулучепреломления, обусловленного кручением spun-световода. Ключевые слова: spun-световод, собственные поляризационные моды, эллиптическое двулучепреломление.
Спектроскопия возбуждения фотолюминесценции массивов квантовых точек InAs/InGaAs/GaAs в температурном диапазоне 20-300 K
Authors: Рыбалко Д.А. , Надточий А.М. , Максимов М.В. , Жуков А.Е.
Published: December 2019

Detailed photoluminescence and photoluminescence excitation (PLE)
studying in temperature range 20-300 K with variation of detection energy of selforganized InAs/InGaAs/GaAs quantum dots is presented in this work. PLE spectra analysis allowed us to identify two types of peaks. First type associated with excited-ground state transitions with high probability. Second corresponds to transitions from excited states to the ground state which probability is small, but significantly increased due to the effective relaxation of carriers with LO phonons. We discovered, that the QD distinctive dependence of the energy difference between peaks spectral positions corresponding to the ground and excited states on the ground state energy (i.e., on the quantum dots size) deviates as the temperature rises to 140–160 K, at which charge carrier transport between QD is activated.
Влияние кислородных вакансий на формирование и структуру филамента в мемристорах на основе диоксида кремния
Authors: Окулич Е.В. , Окулич В.И. , Тетельбаум Д.И.
Published: December 2019

The improvement of the parameters of the SiO2-based memristor is found when creating displacement cascades in the near-surface layer of a silicon dioxide film by irradiation with Xe+ ions. Molecular dynamic modeling of the structure of amorphous SiO2 enriched with oxygen vacancies has shown the possibility of nucleation of silicon nanoclusters, which can play a significant role in the formation and evolution of current conducting paths (filaments) and thereby affect the parameters of the memristor.
Моделирование распределения дисперсной фазы при течении в цилиндрической области методами вычислительной гидродинамики
Authors: Чернышев А.С. , Шмидт А.А.
Published: December 2019

The influence of the diameter of a cylindrical region filled with water on the structure of a bubble polydisperse flow is analyzed. Numerical simulation of the flow is based on a mathematical model that uses the Euler-Euler approach to the description of multiphase media, and includes the heterogeneous MUSIG model for the description of polydispersity, the k-ω-SST turbulence model, and interfacial momentum transfer. The bubble distributions in the sections near the sparger and near the free surface are obtained. The regimes of the bubble flow with full and partial filling of the region are identified and the transition criterion is determined.
Полоса синхронизации магнетрона
Authors: Черноусов Ю.Д. , Шеболаев И.В. , Икрянов И.М. , Болотов В.А. , Танашев Ю.Ю. , Медведев Л.Э. , Воскобойников Р.В.
Published: December 2019

Frequency bandwidth of the injection locked magnetron by an external microwave signal was measured. It is shown that injection locking in a given band requires an order of magnitude less microwave power than follows from recent works. For measurements, a microwave generator based on a magnetron of a household oven with a wide range of changes in pulsed and average microwave power was used. A method for measuring the parameters of strongly coupled resonators is given.
Параметры высоковольтных разрядов на лопастях винтов вертолета и создаваемых ими электромагнитных помех
Authors: Гущин М.Е. , Зудин И.Ю. , Коробков С.В. , Костров А.В. , Микрюков П.А. , Привер С.Э. , Стриковский А.В. , Сысоев В.С.
Published: December 2019

Abstract Parameters of pulsed electric discharges arising between insulated metal parts of helicopter rotor blades, which generate electromagnetic interferences for onboard radio stations operating in the very short wave (VSW) and ultrashort wave (USW) bands have been studied. These discharges appear as a result of the in-flight engine-driven differential charging of helicopters. In-flight and laboratory experiments were used to determine the range of discharge voltages and currents and the amplitude and spectral characteristic of electromagnetic interferences produced by these discharges for onboard antennas.
Дальнодействующее магнитное взаимодействие в гетероструктурах InGaAs/GaAs/delta-< Mn>
Authors: Дорохин М.В. , Дёмина П.Б. , Малышева Е.И. , Кудрин А.В. , Ведь М.В. , Здоровейщев А.В.
Published: December 2019

The low-temperature circularly polarized electroluminescence in InGaAs/GaAs/delta heterostructures was investigated. It was found that the degree of circular polarization weakly depends on the spatial separation of the active region and the magnetic layer and is retained even at a spacer layer thickness of 12 nm. The revealed effect is associated with the long-range interaction of carriers with Mn ions.
THE EFFECT OF MANAGERIAL CAPABILITIES OF PRINCIPAL TOWARD SCHOOL QUALITY IN VOCATIONAL HIGH SCHOOL
Authors: KUSWANA Hasan
Published: December 2019

The figure of principal as top management in schools has an important role in optimizing the function of teachers in accordance with the background of their expertise, particularly to vocational high school, which becomes one of Indonesian’s government priorities. Thus, the aim of the study was to examine the influence of the principal's managerial ability on the quality of vocational high school. The study was conducted at three public vocational schools of Business Management group located in North Jakarta. The study employed a quantitative survey method with 102 teachers as a sample from the teacher population of 138 people. Prior to the research, trials were conducted on 30 teachers. The research reports that direct influence of the principal's managerial ability on the quality of vocational school of business management group is 16%. This figure indicates the direct influence of the Principal's managerial ability on the quality of vocational high Schools. It is concluded that the competency of principal has a major role to bring the success of school as an educational organization and the quality of teachers.
MULHERES NO LAGO DOS CISNES: DESIGUALDADE DE OPORTUNIDADES NO ITAMARATY BRASILEIRO
Authors: Balestero Gabriela Soares
Published: December 2019

O presente estudo busca compreender o feminino e arepresentatividade política feminina na Diplomacia Brasileira. A participação de mulheres na política precisa ser discutida, visto que, em um mundo no qual as injustiças e lutas por igualdade não se restringem apenas ao âmbito doméstico, a participação paritária e representativa das mulheres no espaço público é uma exigência para o avanço da promoção da igualdade de gênero. Assim, o artigo científico pretende analisar teoricamente uma política que traduza as ideias de democracia e inclusão, visto que ainda há baixa presença de mulheres na estrutura de comando do Itamaraty bem como em concursos de admissão à carreira diplomática, trazendo alguns questionamentos e complexidades da própria luta pelo poder em paridade ao masculino que ainda é maioria na carreira diplomática.
SÍNTESE DA EVOLUÇÃO DOS PRINCIPAIS INDICADORES SÓCIO ECONÔMICOS UTILIZADOS COMO MEDIDA DA DESIGUALDADE SOCIAL NO BRASIL ENTRE OS ANOS 2000 E 2015
Authors: Cares Bustamante Paula Margarita Andrea
Published: December 2019

O artigo objetiva apresentar os principais conceitos relacionados ao desenvolvimento e verificar como isso tem se dado no Brasil a partir do ano 2000. Especificamente o trabalho objetiva identificar o comportamento dos indicadores socioeconômicos no Brasil a partir de 2000. A metodologia utilizada na pesquisa será a revisão bibliográfica com base nos textos de Souza (2012) e Paulani; Braga (2007) que apresentam as teorias de desenvolvimento econômico, Jannuzzi (2012) trabalha o conceito de indicadores sociais e, Neri e Souza (2012); Oxfam (2017) apresentam o comportamento dos principais índices sociais no Brasil ao longo da década 2000 e descrevem a importância e limitação dos indicadores sociais. Constatou-se que o crescimento econômico no período analisado, junto com a redução das desigualdades de renda, favoreceu a melhoria das condições de vida da população brasileira.
INFORMAÇÕES DOS CLIENTES E A INOVAÇÃO NOS PEQUENOS NEGÓCIOS DA REGIÃO DO CARIRI PARAIBANO
Authors: Linhares Thaiguara Martins da Silva , Frascaroli Bruno Ferreira , Guimarães Maria Amélia Dutra , Lima Correio José De Arimatéia Augusto de
Published: December 2019

Neste trabalho são analisadas informações a partir de uma amostra de trinta e cinco pequenos empreendimentos no estado da Paraíba, atendidas pelo Programa Agentes Locais de Inovação (Programa ALI), no ciclo 2014-2016. O objetivo desse estudo é compreender o grau de inovação das MPEs na região do Cariri Ocidental Paraibano, a partir das informações das suas carteiras de clientes. A estratégia empírica consistiu em analisar as informações geradas a parir do Radar da Inovação – ferramenta utilizada pelos agentes locais de inovação para medir o grau de inovação das empresas, bem investigar como características e correlações entre as dimensões da inovação. Controlou-se os resultados também para o grupo das empresas mais inovadoras na dimensão clientes, e foi revelado que a identificação de necessidades dos clientes e o uso das informações dos mesmos foi importante para aumentar seu grau de inovação. Conclui-se que além das dificuldades gerais dos pequenos negócios no Brasil, intensificada pela crise econômica, houve implementação de ações de baixo custo, mas que ainda não conseguiram tornar a inovação um processo endógeno.
O PERFIL DOS CONSUMIDORES DE PRODUTOS ORGÂNICOS DA CIDADE DE SANTA MARIA-RS
Authors: Pohl Natália Heinze , Pereira Filho João Batista Corrêa , Abbade Eduardo Botti
Published: December 2019

Produtos orgânicos adquiriram grande atenção dos mercados e da sociedade, pois o mercado e a demanda por produtos orgânicos vêm crescendo de forma significativa em todo o mundo. Este estudo teve como objetivo analisar o perfil demográfico e comportamental do consumidor de produtos orgânicos. Foi realizado um estudo de levantamento por meio de uma pesquisa de campo com aplicação de questionário com uma amostra por adesão de 206 respondentes. Após a coleta, os dados obtidos foram tabulados e posteriormente analisados com o auxílio do software Excel. O estudo encontrou um perfil de consumidores de alimentos orgânicos de maioria do gênero feminino, com alta escolaridade, solteiro e sem filhos. A preocupação com a saúde é o principal motivo para o consumo de orgânicos, mas a maioria não tem total confiança de que os alimentos que compram como orgânicos o sejam totalmente orgânicos. Os respondentes que não consomem orgânicos afirmam como principal motivo a falta de acesso, o que mostra que há uma demanda no mercado por esses produtos, cuja oferta é muito baixa em relação ao alimento convencional.
[ID 37442] PROBLEMA CRÔNICO DE COLUNA E FATORES ASSOCIADOS: UM ESTUDO BASEADO NA PESQUISA NACIONAL DE SAÚDE 2013
Authors: Bernardelli Luan Vinícius , Pereira Camila
Published: December 2019

Objetivo: O presente estudo teve como objetivo identificar os possíveis fatores de risco para os Problemas Crônicos de Coluna (PCC), como também os fatores que podem se comportar como protetores para o desenvolvimento desse problema, em adultos com 18 anos ou mais de idade. Material e Métodos: A base de dados utilizada foi da Pesquisa Nacional de Saúde de 2013, disponibilizada pelo IBGE em parceria com o Ministério da Saúde. Resultados: Aproximadamente 27 mil indivíduos se enquadraram neste estudo, dos quais aproximadamente 16% relataram ter PCC. Destes, 46% não realizavam tratamento algum e 62% relataram que esses problemas geravam algum tipo de limitação. Os resultados encontrados foram relevantes, em virtude da confirmação de evidências importantes contidas na literatura, ou seja, identificaram-se fatores de risco e de proteção no desenvolvimento do PCC, como o de que mulheres apresentam maiores chances de desenvolverem PCC. Quando analisado a realização de exercício físico, este demonstrou ser um fator de proteção, diminuindo em 9% a chance de desenvolver problema na coluna. Conclusão: Em geral, o Logit dessa investigação classificou 84,4% das observações, contudo, é certo que existem muitos fatores envolvidos no desenvolvimento dos PCC e o conhecimento desses é de extrema importância, visto que medidas preventivas podem ser aplicadas.

DESCRITORES: Dor nas costas. Fatores de risco. Modelo Logístico.
[ID 41272] LIMITAÇÃO DE ATIVIDADE E CONSCIÊNCIA DE RISCO EM CLIENTES ACOMETIDOS PELA HANSENÍASE
Authors: Costa Carla Rossana Lima , Brito Karen Krystine Gonçalves , Mônica Valéria Morais de Oliveira  , Mirian Alves Silva  , Soares Maria Julia Guimarães Oliveira
Published: December 2019

Objetivo: Caracterizar a limitação de atividade e a consciência de risco entre pacientes com hanseníase e analisar a correlação entre os escores da escala SALSA para limitação com a Classificação Operacional, Forma Clínica, Reação Hansênica e Consciência de Risco. Material e Métodos: Estudo descritivo, seccional, quantitativo realizado com indivíduos com hanseníase utilizando a Screening of Activity Limitation and Safety Awarenes (Escala SALSA) para diagnóstico situacional. Para análise dos dados adotou-se o software estatístico SPSS 20.0. Resultados: O perfil sociodemográfico da amostra aponta elevados índices de detecção da doença na população masculina (70,5%), com escolaridade de nível fundamental (58,8%), baixa renda, em faixa etária economicamente produtiva. A faixa etária oscilou entre 15 e 69 anos. Identificou-se leve limitação (escores 25 a 39) e baixa consciência de risco (escores 0 a 5), havendo forte significância estatística entre as mesmas (p=0,001). Verificou-se correlação positiva da limitação de atividade com a reação hansênica (r=0,068) e a consciência de risco (r=0,801). Observou-se ainda que a consciência de risco foi baixa em todos os aspectos, contudo estiveram correlacionadas as formas mais graves da doença e aos clientes que já apresentavam alguma limitação. Conclusão: A existência de limitação para AVD’s, embora em categoria leve, bem como nenhuma e baixa consciência de risco sinalizam para a necessidade de fortalecimento de ações de prevenção das incapacidades, dentre as quais, a educação em saúde consolida-se como ferramenta relevante, mediadora de reversibilidade destas consequências.

DESCRITORES: Hanseníase. Risco. Limitação Crônica da Atividade.
[ID 44150] AVALIAÇÃO DO TEOR DE SÓDIO CONTIDO EM SALGADINHOS INDUSTRIALIZADOS COMERCIALIZADOS EM SUPERMERCADOS DA CIDADE DE MACEIÓ, ALAGOAS
Authors: Sousa Maria Clara Domingos de Araújo , Barros Yáskara Veruska Ribeiro , Silva Vânia Nascimento Tenório , Santos Júnior Claudio José dos
Published: December 2019

Objetivo: Analisar experimentalmente o teor de sódio de salgadinhos industrializados disponíveis no comércio da Cidade de Maceió, Alagoas. Material e Métodos: Classificar o teor de sódio de acordo com a legislação vigente. Vinte amostras de salgadinho de milho, trigo e batata, de diferentes sabores foram avaliadas utilizando-se a metodologia de espectrofotometria de emissão com atomização em chama. Resultados: Verificou-se que todas as amostras apresentavam a classificação de “alto teor” de sódio, tendo por base a RDC n° 24 de 2010 da Anvisa e que 65% das amostras apresentaram valores reais do teor de sódio superiores aos que estavam declarados nos rótulos. Conclusão: Com relação ao teor de sódio encontrado nos salgadinhos analisados, verificou-se que todas as amostras apresentaram a classificação de “alto teor” de sódio.

DESCRITORES: Teor de Sódio. Salgadinhos Industrializados. Informação Nutricional.
[ID 44861] NÍVEL DE FLEXIBILIDADE DE ADOLESCENTES PRATICANTES DE JIU-JITSU E JUDÔ: UM ESTUDO COMPARATIVO
Authors: Ferreira Andre Fellipe , Moratelli Jéssica , Carsten Junior Marcelo Miguel Correa , Boing Leonessa , Guimarães Adriana Coutinho de Azevedo
Published: December 2019

Objetivo: O estudo de delineamento transversal objetivou investigar a flexibilidade de adolescentes praticantes de jiu-jitsu e judô participantes de projetos sociais. Metodologia: Participaram 74 adolescentes de ambos os sexos, com idade entre 10 e 17 anos, que responderam um questionário em forma de entrevista: a) informações gerais e b) flexibilidade. Resultados: A frequência de treino de 3 a 4 vezes por semana teve diferença significativa sendo os praticantes de judô com maior porcentagem (82%) quando comparados com os de jiu-jitsu (30%). A maioria dos adolescentes encontram-se em condição de risco para a flexibilidade de quadril. Conclusão: Concluiu-se que em ambas as modalidades os adolescentes encontram-se em condições atléticas para flexibilidade de ombros, no entanto, para a flexibilidade de quadril parece haver a necessidade de uma maior prática nas aulas para o aumento da mesma.

DESCRITORES: Adolescentes. Jiu-jitsu. Judô.
[ID 44983] AVALIAÇÃO DOS NÍVEIS PRESSÓRICOS E ANTROPOMÉTRICOS DE ESCOLARES NO INTERIOR DO NORDESTE BRASILEIRO
Authors: Rafaela Góis de Mendonça  , Bianca Vanessa dos Santos Ribeiro  , Laís Lima de Oliveira  , Tiago da Silva Nunes  , Diego Moura Tanajura
Published: December 2019

Objetivo: Avaliar a influência do excesso de peso nos valores de pressão arterial (PA) de escolares 4 a 17 anos em uma cidade no interior de Sergipe. Metodologia: Trata-se de um estudo transversal, em que foram avaliados 119 estudantes de 5 escolas, por meio de avaliação antropométrica e obtenção dos valores da PA. Os estudantes foram classificados quanto seu estado nutricional e a presença de níveis pressóricos alterados de acordo com os percentis propostos pela Organização Mundial da Saúde e da Sociedade Brasileira de Cardiologia, respectivamente. Em seguida, os dados foram analisados estatisticamente com o programa GraphPad Prism V7.0., utilizando-se o teste de Mann Whitney para comparação e o coeficiente de Spearman para correlação entre duas variáveis, sendo adotado como nível de significância, 5%. Resultados: Dos 119 estudantes avaliados, 8,41% foram considerados com baixo peso, 38,32% eutróficos e 53,27% com excesso de peso. Os estudantes com excesso de peso apresentaram maiores medidas de circunferência abdominal. Observou-se uma correlação forte e positiva entre os valores de IMC-z e a razão CA/A, em que os estudantes com maiores valores de IMC-z possuíam também valores maiores da relação CA/A. Além disso, foi constatado maior número de estudantes com níveis considerados PA alterados, dentre aqueles que possuíam maiores medidas tanto de IMC-z e quanto da relação CA/A. Conclusão: Crianças e adolescentes com PA alterada apresentaram maior média de IMC e maior relação CA/A em comparação com as que possuíam PA normal, o que evidencia a necessidade de intervenção nessa população para prevenção e promoção da saúde.

DESCRITORES: Obesidade. Sobrepeso. Pressão Arterial. Criança. Adolescente. Saúde Pública.
What makes a board director better connected? Evidence from graph theory
Authors: Samarbakhsh Laleh , Tasic Boza
Published: December 2019

We are interested in quantifying and uncovering the relationships that form between the board directors of companies. Using these relationships we compute three network centrality measures for each director in the network and employ them in the analysis of connectedness of directors. Our focus in this study is on the attributes that make a board member better connected. The biological, educational and experiential attributes are used as independent variables to develop a regression model measuring the impact on the three connectivity measures (degree, betweenness and closeness). Our results show that ?Age? has a direct significant impact on all connectedness measures of a board member. We also find that female directors have a higher measure of degree centrality and betweenness centrality, but lower closeness. The number of foreign degrees increases the degree centrality and betweenness centrality but not closeness. The three identified characteristics of ?Age?, ?Gender?, and ?Education? are supporting the idea that a high level of social connection can in part be expected by the characteristics of individual board members and can explain up to 25% of the board member?s connectivity.
“Sticking It to Them”—Reducing Migration of Peripherally Inserted Central Catheters
Authors: Ralph Webber Joan L. , Maningo-Salinas Marie J. (Jay)
Published: December 2019

Highlights

TA for stabilization and securement of PICCs reduced catheter migration. This solution to catheter migration was safe, inexpensive, and highly effective. TA reduced migration rates from 19.35% to 1.4% in more than 411 inpatients. There was no evidence of phlebitis, cellulitis, or microbial contamination. There also was no evidence of central line infections.
2019 Update to: Management of Hyperglycemia in Type 2 Diabetes, 2018. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)
Authors: Buse John B. , Wexler Deborah J. , Tsapas Apostolos , Rossing Peter , Mingrone Geltrude , Mathieu Chantal , D’Alessio David A. , Davies Melanie J.
Published: December 2019

The American Diabetes Association and the European Association for the Study of Diabetes have briefly updated their 2018 recommendations on management of hyperglycemia, based on important research findings from large cardiovascular outcomes trials published in 2019. Important changes include: 1) the decision to treat high-risk individuals with a glucagon-like peptide 1 (GLP-1) receptor agonist or sodium–glucose cotransporter 2 (SGLT2) inhibitor to reduce major adverse cardiovascular events (MACE), hospitalization for heart failure (hHF), cardiovascular death, or chronic kidney disease (CKD) progression should be considered independently of baseline HbA1c or individualized HbA1c target; 2) GLP-1 receptor agonists can also be considered in patients with type 2 diabetes without established cardiovascular disease (CVD) but with the presence of specific indicators of high risk; and 3) SGLT2 inhibitors are recommended in patients with type 2 diabetes and heart failure, particularly those with heart failure with reduced ejection fraction, to reduce hHF, MACE, and CVD death, as well as in patients with type 2 diabetes with CKD (estimated glomerular filtration rate 30 to ≤60 mL min–1 [1.73 m]–2 or urinary albumin-to-creatinine ratio >30 mg/g, particularly >300 mg/g) to prevent the progression of CKD, hHF, MACE, and cardiovascular death.
EDUCAÇÃO APÓS A INTRUSÃO DE GAIA: E O QUEER TEM A VER COM ISSO?
Authors: Ranniery Thiago
Published: December 2019

Neste texto, inspirado pela formulação de Isabelle Stengers sobre a intrusão de Gaia, busco explorar relações entre política de currículo, ecologia política e crítica queer em nossa era chamada de Antropoceno. A partir de intercessores da literatura e do teatro, argumento, por um lado, a possibilidade de existir experiência educacional por fora da retórica do primado do sujeito humano como projeto de formação do currículo no passo que, para tanto, insisto que necessitamos de práticas queers que nos desloquem das formas habituais de pensar à política, ecologia e natureza. Mobilizo, assim, a imaginação cosmoecológica da ética bicha para perturbar as histórias esmagadoras do gêmeo tributário do sujeito da educação, o puído antropocentrismo, que, vai não vai, surge revigorado, confundido com a própria matéria do currículo. Ao fim, sugiro que política curricular está mais para um experimento de estar mundo, de criar mundos, de encontrar um mundo, de encontrar modos de estar em circuitos de forças de transfigurações alquímicas; uma ecologia estético-política em que se desdobram trajetórias muito além – ou mesmo aquém – dos modelos humanistas de reconhecimento ou dos registros hiperintelingíveis usuais da normatividade e do Estado.