bluuebunny/crossref_metadata_2025 huggingface dataset:
Alzheimer’s Disease Frontal Cortex Mitochondria Show a Loss of Individual Respiratory Proteins but Preservation of Respiratory Supercomplexes
Authors: Kenney Paula M. , Bennett James P.
Published: March 2019

Alzheimer’s disease (AD), the most common cause of sporadic dementia of in adults, shows increased risk of occurrence with aging and is destined to become a major sociomedical tragedy over the next few decades. Although likely complex in origin, sporadic AD is characterized by a progressive and stereotyped neuropathology with aggregated protein deposition (esp beta amyloid (BA) and hyperphosphorylated tau (P-tau)) and neuronal degeneration. To date, prevention of BA synthesis or immune-mediated removal of BA has failed to alter AD progression. Development and testing of P-tau therapeutics are a work in progress. AD brain tissues show multiple system deficits, including loss of respiratory capacity. In the present study there were no differences in mitochondrial mass between AD and CTL samples. We examined mitochondrial preparations of postmortem AD and CTL frontal cortex for relative levels of individual respiratory protein complexes by Western immunoblotting. ANOVA revealed deficiencies of all respiratory complex subunits in AD; post-ANOVA t-testing revealed significant differences in levels of subunits for complexes II, III, and V, borderline significance for subunit of complex IV, and no difference for subunit of complex I. We also examined mitochondrial extracts with blue-native gel electrophoresis combined with immunoblotting for subunits of complexes I and III to search for “respiratory supercomplexes” (RSC’s). We found that levels of RSC’s did not differ between AD and CTL samples. Mitochondrial preparations from end-stage AD brain tissue showed loss of individual ATP-producing respiration subunits but preservation of levels of assembled respiratory subunits into RSC’s. Possible explanations include insufficient sensitivity of our method of RSC detection to find loss of individual subunits, or normal levels of RSC’s in AD brain mitochondria coupled with decreased levels of nonassembled respiratory complex subunits. Disease-altering therapies of early AD could include stimulation of mitochondrial biogenesis to overcome loss of respiratory subunits.
Sliding Mode Controllers for Standalone PV Systems: Modeling and Approach of Control
Authors: Chaibi Y. , Salhi M. , El-jouni A.
Published: March 2019

This paper presents a single-phase standalone photovoltaic (PV) system with two stages of converters. The aim of this work is to track the maximum power point (MPP) so as to transfer the maximum available power to the load and to control the output current in order to feed the AC load by a sinusoidal current. These goals are attained by using the sliding mode to design control laws in order to command the boost DC-DC and the inverter switches. Thus, a maximum power point tracking (MPPT) and an output current controller based on the sliding mode are proposed. The innovative aspect of this work is to propose a standalone PV system with the controllers based only on the sliding mode control approach. The proposed system is modeled and simulated under MATLAB Simulink under fast variations of irradiance and temperature. Then, the obtained results using the suggested MPPT are compared to those using the incremental conductance (IC) method. These results demonstrate the superiority of the sliding mode MPPT in terms of the tracking speed, the efficiency, and the time of response. Moreover, the current controller provides an output current of high quality with a THD of 3.47%. Furthermore, for accurate results, these controllers are evaluated under the fluctuations of two daily climatic profiles (sunny and cloudy) and compared those of the IC method. The results illustrate that the sliding mode MPPT has the potential of generating more electrical energy than the IC MPPT with benefits of up to 13.02% for the sunny daily profile and 27.57% for the cloudy one.
A General Method for Transforming Nonphysical Configurations in BPS States
Authors: Santos J. R. L. , Dutra A. de Souza , Winter O. C. , Correa R. A. C.
Published: March 2019

In this work, we apply the so-called BPS method in order to obtain topological defects for a complex scalar field Lagrangian introduced by Trullinger and Subbaswamy. The BPS approach led us to compute new analytical solutions for this model. In our investigation, we found analytical configurations which satisfy the BPS first-order differential equations but do not obey the equations of motion of the model. Such defects were named nonphysical ones. In order to recover the physical meaning of these defects, we proposed a procedure which can transform them into BPS states of new scalar field models. The new models here founded were applied in the context of hybrid cosmological scenarios, where we derived cosmological parameters compatible with the observed Universe. Such a methodology opens a new window to connect different two scalar fields systems and can be implemented in several distinct applications such as Bloch Branes, Lorentz and Symmetry Breaking Scenarios, Q-Balls, Oscillons, Cosmological Contexts, and Condensed Matter Systems.
Slippery Stents: A Case Report and Review of the Literature Describing Patients with May-Thurner Syndrome That Experienced Stent Migration
Authors: Mando Ramy , Sigua-Arce Priscilla , Spencer Lisa , Halalau Alexandra
Published: March 2019

Endovascular stent placement is an effective treatment for relieving chronic venous obstruction in patients with May-Thurner Syndrome (MTS) with or without the presence of thrombotic lesions. Stent migration is a rare but potentially life-threatening complication of endovascular stenting. Herein, we describe a case of stent migration from the left common iliac vein into the right heart, requiring open-heart surgery. We also completed a literature review of MTS patients with stent migration in hopes of raising awareness of this rare and life-threatening complication.
Achieving Better Function through Combining Orthodontics and Restorative Dentistry in the Case of Dental Abrasions
Authors: Giacobbo Laís C. , Guimarães Lara Karolina , Fornazari Isabelle Adad , Meda Eduardo Monteiro , Tanaka Orlando Motohiro
Published: March 2019

This case report describes the orthodontic treatment used to prepare for restorative dentistry, aimed at the functional rehabilitation of an adult patient with Class I malocclusion, right posterior crossbite, and significant tooth wear on the palatal face of the maxillary canine to canine. The orthodontic treatment was performed with a total fixed appliance mini-expandex-type expander, associated with vertical elastics. Good dental intercuspation was obtained and enabled conditions for the restoration of the abrasions on the palatal surfaces of the maxillary incisors and canines and the tips of the buccal cusps of the maxillary right premolars and first molar. Excellent results were found during a 37-month follow-up.
Path Choice of Emergency Logistics Based on Cumulative Prospect Theory
Authors: Zhu Chang-feng , Zhang Zheng-kun , Wang Qing-rong
Published: March 2019

We study the problem of path choice for emergency logistics in this paper. Based on the uncertainty environment during the path choice from emergency logistics network and the bounded rationality of decision makers, cumulative prospect theory is introduced to study the problem of emergency logistics path choice with comprehensive consideration of path properties and risk attitude of decision makers. In addition, the decision behavior of decision maker with the attitude of risk seeking and risk aversion under limited rationality is comprehensively analyzed respectively. Based on the choice behavior, a strategy to demarcate the value of reference point value is also proposed, and an optimization model is used to obtain the combined weight based on the moment estimation. Finally, both the theory and model are verified by calculation and compared analysis in a case study. In addition, perturbation analyses of related parameter are carried out to further reveal the influence mechanism between the prospect value of each path and related parameters. The result shows that the decision-making model can make emergency logistics path choice with higher efficiency and reliability under different complex interference conditions.
Interaction Topologies in Mobile-Based Situated Networked Music Systems
Authors: Matuszewski Benjamin , Schnell Norbert , Bevilacqua Frederic
Published: March 2019

In this paper, we present a complete framework, both technical and conceptual, aimed at developing and analysing Networked Music Systems. After a short description of our technical framework called soundworks, a JavaScript library especially designed for collective music interaction using web browser of mobile phones, we introduce a new conceptual framework, we named interaction topologies, that aims at providing a generic tool for the description of interaction in such systems. Our proposition differs from the theoretical approaches generally proposed in the literature by decoupling the description of interaction topologies from the low level technical implementation of the network. We then report on a set of scenarios and prototypes, illustrating and assessing our framework, which were successfully deployed in several public installations and performances. We particularly show that our concept of interaction topologies succeeds at describing and analysing global aspects of interaction from multiple point of views (e.g., social, human-computer) by allowing for composing simple abstract figures. We finally introduce a discussion on agencies and perception of users engaged in such systems that could later complete our framework to conceive and analyse Networked Music Systems.
Multi-Omics Profiling Reveals Distinct Microenvironment Characterization and Suggests Immune Escape Mechanisms of Triple-Negative Breast Cancer
Authors: Xiao Yi , Ma Ding , Zhao Shen , Suo Chen , Shi Jinxiu , Xue Meng-Zhu , Ruan Miao , Wang Hai , Zhao Jingjing , Li Qin , Wang Peng , Shi Leming , Yang Wen-Tao , Huang Wei , Hu Xin , Yu Ke-Da , Huang Shenglin , Bertucci François , Jiang Yi-Zhou , Shao Zhi-Ming
Published: March 2019

Purpose:

The tumor microenvironment has a profound impact on prognosis and immunotherapy. However, the landscape of the triple-negative breast cancer (TNBC) microenvironment has not been fully understood.

Experimental Design:

Using the largest original multi-omics dataset of TNBC (n = 386), we conducted an extensive immunogenomic analysis to explore the heterogeneity and prognostic significance of the TNBC microenvironment. We further analyzed the potential immune escape mechanisms of TNBC.

Results:

The TNBC microenvironment phenotypes were classified into three heterogeneous clusters: cluster 1, the “immune-desert” cluster, with low microenvironment cell infiltration; cluster 2, the “innate immune-inactivated” cluster, with resting innate immune cells and nonimmune stromal cells infiltration; and cluster 3, the “immune-inflamed” cluster, with abundant adaptive and innate immune cells infiltration. The clustering result was validated internally with pathologic sections and externally with The Cancer Genome Atlas and METABRIC cohorts. The microenvironment clusters had significant prognostic efficacy. In terms of potential immune escape mechanisms, cluster 1 was characterized by an incapability to attract immune cells, and MYC amplification was correlated with low immune infiltration. In cluster 2, chemotaxis but inactivation of innate immunity and low tumor antigen burden might contribute to immune escape, and mutations in the PI3K-AKT pathway might be correlated with this effect. Cluster 3 featured high expression of immune checkpoint molecules.

Conclusions:

Our study represents a step toward personalized immunotherapy for patients with TNBC. Immune checkpoint inhibitors might be effective for “immune-inflamed” cluster, and the transformation of “cold tumors” into “hot tumors” should be considered for “immune-desert” and “innate immune-inactivated” clusters.
Direct CDKN2 Modulation of CDK4 Alters Target Engagement of CDK4 Inhibitor Drugs
Authors: Green Jennifer L. , Okerberg Eric S. , Sejd Josilyn , Palafox Marta , Monserrat Laia , Alemayehu Senait , Wu Jiangyue , Sykes Maria , Aban Arwin , Serra Violeta , Nomanbhoy Tyzoon
Published: March 2019

The interaction of a drug with its target is critical to achieve drug efficacy. In cases where cellular environment influences target engagement, differences between individuals and cell types present a challenge for a priori prediction of drug efficacy. As such, characterization of environments conducive to achieving the desired pharmacologic outcome is warranted. We recently reported that the clinical CDK4/6 inhibitor palbociclib displays cell type–specific target engagement: Palbociclib engaged CDK4 in cells biologically sensitive to the drug, but not in biologically insensitive cells. Here, we report a molecular explanation for this phenomenon. Palbociclib target engagement is determined by the interaction of CDK4 with CDKN2A, a physiologically relevant protein inhibitor of CDK4. Because both the drug and CDKN2A prevent CDK4 kinase activity, discrimination between these modes of inhibition is not possible by traditional kinase assays. Here, we describe a chemo-proteomics approach that demonstrates high CDK4 target engagement by palbociclib in cells without functional CDKN2A and attenuated target engagement when CDKN2A (or related CDKN2/INK4 family proteins) is abundant. Analysis of biological sensitivity in engineered isogenic cells with low or absent CDKN2A and of a panel of previously characterized cell lines indicates that high levels of CDKN2A predict insensitivity to palbociclib, whereas low levels do not correlate with sensitivity. Therefore, high CDKN2A may provide a useful biomarker to exclude patients from CDK4/6 inhibitor therapy. This work exemplifies modulation of kinase target engagement by endogenous proteinaceous regulators and highlights the importance of cellular context in predicting inhibitor efficacy.
Relative Factors Analysis of Imatinib Trough Concentration in Chinese Patients with Gastrointestinal Stromal Tumor
Authors: Wu Xingye , Li Juan , Zhou Yi , Mao Yun , Luo Shiqiao , He Xuemei , Wang Li , Shen Yifan , Zhang Hua , Yang Longwei , Zhang Jun
Published: March 2019

Aims: Imatinib plasma trough levels (IM Cmin) have been reported to have a considerable clinical impact in patients with gastrointestinal stromal tumors (GISTs). We therefore have investigated the factors affecting IM plasma concentration in Chinese GIST patients. Methods: IM Cmin in 190 patients with GIST who were taking IM were measured. Results: In patients treated with IM 300 mg/day (n = 16), 400 mg/day (n = 168), and > 400 mg/day (500: n = 1, 600: n = 5), IM Cmin was 1,564.54 ± 596.15, 1,521.26 ± 610.33, and 2,540.31 ± 1,298.14 ng/mL, respectively. Of the 168 patients treated with IM 400 mg/day, IM Cmin was significantly lower in males (1,353.94 ± 492.89 ng/mL) than in females (1,680.79 ± 669.03 ng/mL, p < 0.01), and in patients with gastrectomy (1,439.60 ± 587.66 ng/mL) than those without gastrectomy (1,649.88 ± 620.12 ng/mL) (p = 0.033). High IM Cmin was correlated with low body weight (p = 0.004) and low body surface area (p < 0.001). Conclusion: IM Cmin at steady state was significantly associated with body weight and body surface area. Monitoring of IM Cmin might be particularly important for the optimal treatment with IM of male patients and those who have undergone gastrectomy.
A Prospective Study Evaluating the Effects of SSRI Exposure on Cardiac Size and Function in Newborns
Authors: Ansah Deidra A. , Reinking Benjamin E. , Colaizy Tarah T. , Roghair Robert D. , Haskell Sarah E.
Published: March 2019

Background: Selective serotonin reuptake inhibitors (SSRIs) are antidepressants prescribed in 10% of pregnancies in the USA. We have previously shown in preclinical studies that sertraline exposure impacts cardiomyocyte development, leading to reductions in left ventricular size and cardiac function. Objectives: We hypothesized that in utero SSRI exposure will lead to reduced left ventricular dimensions and cardiac function on echocardiography immediately after birth. Methods: Twenty term infants with and 21 term infants without in utero exposure to SSRIs underwent echocardiograms to assess cardiac size and function. The exclusion criteria for infants were prematurity, small or large for gestational age, any respiratory or cardiovascular support needed after birth, and any major congenital malformation. Results: Infants exposed to in utero SSRIs had significantly reduced right ventricular dimensions in the diastole (controls 1.0 cm [0.86, 1.20], SSRI 0.89 cm [0.730, 1.05], p = 0.03), and left ventricular lengths in the diastole and systole (diastole: controls 3.4 cm [3.25, 3.65], SSRI 3.25 cm [3.10, 3.45], p = 0.03; systole: controls 2.9 cm [2.65, 3.05], SSRI 2.6 cm [2.50, 2.85], p = 0.01). No differences were observed in cardiac function. Importantly, there were no differences in maternal conditions or infant birth weight, body surface area, or gestational age. Conclusions: Our findings suggest an association between in utero exposure to SSRIs and ventricular size in infants. Given the increasing use of SSRIs during pregnancy and the importance of early life programming on future cardiovascular health, larger studies need to be completed to determine if in utero SSRI exposure impacts ventricular size.
Neurological Symptoms in Danes with a History of Poliomyelitis: Lifelong Follow-Up of Late Symptoms, their Association with Initial Symptoms of Polio, and Presence of Postpolio Syndrome
Authors: Kay Lise , Nielsen Nete Munk , Wanscher Benedikte , Jennum Poul
Published: March 2019

Background: Previous studies suggest that patients with a history of poliomyelitis (PM) later in life experience a variety of symptoms. These studies were carried out in patients who later in life were admitted to hospital or became members of polio societies and may therefore not be representative of all polio patients. Little data have been published concerning patients actually discharged from hospital with a diagnosis of acute paralytic PM. Objectives: The aim of this study was to compare the prevalence of late symptoms in individuals with a history of paralytic PM with that of controls, and to study whether late symptoms in individuals with a history of PM were associated with symptoms at the acute stage of polio, and finally to compare the prevalence of symptoms in polio patients with postpolio syndrome (PPS) with the prevalence of symptoms in polio patients without PPS. Methods: A questionnaire concerning various symptoms was sent to a previously established cohort of patients, who during the polio epidemics were discharged from the Department of Infectious Disease at Blegdamshospitalet, Copenhagen, with a diagnosis of paralytic PM, and to age- and gender-matched controls without PM. Information about symptoms at the acute stage of disease was obtained from hospital records. Logistic regression analysis with adjustment for age and gender was applied to compare the occurrence of late symptoms in cases and controls and within the above-mentioned groups of individuals with a history of PM. Results: (i) Compared with controls, individuals with a history of polio significantly more often reported muscle symptoms, pain, neuropathic sensory symptoms, and bulbar symptoms; (ii) the occurrence of symptoms did not seem to be related to symptoms of the initial PM; and (iii) symptom prevalence was significantly higher in individuals with a history of polio who reported PPS as compared with those who did not. Conclusion: Our data indicate that individuals with a history of PM late in life experience a variety of symptoms that cannot be attributed to lesions of the anterior horn. Furthermore, late symptoms do not seem to be related to initial symptoms of the acute stage of PM but to reported PPS. The last finding supports the perception that the cause of PPS is not just normal ageing.
Allogeneic Leukocyte-Reduced Red Blood Cell Transfusion Is Associated with Postoperative Infectious Complications and Cancer Recurrence after Colon Cancer Resection
Authors: Deeb Andrew-Paul , Aquina Christopher T. , Monson John R.T. , Blumberg Neil , Becerra Adan Z. , Fleming Fergal J.
Published: March 2019

Background/Aims: Transfusion rates in colon cancer surgery are traditionally very high. Allogeneic red blood cell (RBC) transfusions are reported to induce immunomodulation that contributes to infectious morbidity and adverse oncologic outcomes. In an effort to attenuate these effects, the study institution implemented a universal leukocyte reduction protocol. The purpose of this study was to examine the impact of leukocyte-reduced (LR) transfusions on postoperative infectious complications, recurrence-free survival, and overall survival (OS). Methods: In a retrospective study, patients with stage I–III adenocarcinoma of the colon from 2003 to 2010 who underwent elective resection were studied. The primary outcome measures were postoperative infectious complications and recurrence-free and OS in patients that received a transfusion. Bivariate and multivariable regression analyses were performed for each endpoint. Results: Of 294 patients, 66 (22%) received a LR RBC transfusion. After adjustment, transfusion of LR RBCs was found to be independently associated with increased infectious complications (OR 3.10, 95% CI 1.24–7.73), increased odds of cancer recurrence (hazard ratio [HR] 3.74, 95% CI 1.94–7.21), and reduced OS when ≥3 units were administered (HR 2.24, 95% CI 1.12–4.48). Conclusion: Transfusion of LR RBCs is associated with an increased risk of infectious complications and worsened survival after elective surgery for colon cancer, irrespective of leukocyte reduction.
Interleukin-35 Promotes Macrophage Survival and Improves Wound Healing After Myocardial Infarction in Mice
Authors: Jia Daile , Jiang Hao , Weng Xinyu , Wu Jian , Bai Peiyuan , Yang Wenlong , Wang Zeng , Hu Kai , Sun Aijun , Ge Junbo
Published: March 2019

Rationale:

Targeting inflammation has been shown to provide clinical benefit in the field of cardiovascular diseases. Although manipulating regulatory T-cell function is an important goal of immunotherapy, the molecules that mediate their suppressive activity remain largely unknown. IL (interleukin)-35, an immunosuppressive cytokine mainly produced by regulatory T cells, is a novel member of the IL-12 family and is composed of an EBI3 (Epstein-Barr virus–induced gene 3) subunit and a p35 subunit. However, the role of IL-35 in infarct healing remains elusive.

Objective:

This study aimed to determine whether IL-35 signaling is involved in healing and cardiac remodeling after myocardial infarction (MI) and, if so, to elucidate the underlying molecular mechanisms.

Methods and Results:

IL-35 subunits (EBI3 and p35), which are mainly expressed in regulatory T cells, were upregulated in mice after MI. After IL-35 inhibition, mice showed impaired infarct healing and aggravated cardiac remodeling, as demonstrated by a significant increase in mortality because of cardiac rupture, decreased wall thickness, and worse cardiac function compared with wild-type MI mice. IL-35 inhibition also led to decreased expression of α-SMA (α-smooth muscle actin) and collagen I/III in the hearts of mice after MI. Pharmacological inhibition of IL-35 suppressed the accumulation of Ly6C
low
and major histocompatibility complex II
low
/C-C motif chemokine receptor type 2
−
(MHC II
low
CCR2
−
) macrophages in infarcted hearts. IL-35 activated transcription of CX3CR1 (C-X3-C motif chemokine receptor 1) and TGF (transforming growth factor) β1 in macrophages by inducing GP130 signaling, via IL12Rβ2 and phosphorylation of STAT1 (signal transducer and activator of transcription family) and STAT4 and subsequently promoted Ly6C
low
macrophage survival and extracellular matrix deposition. Moreover, compared with control MI mice, IL-35–treated MI mice showed increased expression of α-SMA and collagen within scars, correlating with decreased left ventricular rupture rates.

Conclusions:

IL-35 reduces cardiac rupture, improves wound healing, and attenuates cardiac remodeling after MI by promoting reparative CX3CR1
+
Ly6C
low
macrophage survival.
Anticoagulation for Atrial Fibrillation in Cirrhosis of the Liver: Are Low‐Dose Non‐Vitamin K Oral Anticoagulants a Reasonable Alternative to Warfarin?
Authors: Gallagher Celine , Sanders Prashanthan , Wong Christopher X.
Published: March 2019

See Article by
Lee et al
Staking the Subject: The Self's Own Gamble with Art
Authors: Damisch Hubert
Published: March 2019

Devoted to the Freud-Signorelli case, this study by French art-historian/philosopher Hubert Damisch offers an in-depth analysis of “the implication of the subject in the various dimensions of perception, remembering, analysis, and interpretation.” To better reflect the complex relationships between art, psychoanalysis, and interpretation, Damisch's commentaries take the form of a diary. By discussing his comings and goings between the 1960s and 1990s and by making an effort to remember his own life and practice, Damisch builds a dispositif where Freud's analyses of the mechanisms of oblivion, Signorelli's painting of “the damned,” Dante's Inferno, and Primo Levi's testimony on the Shoah reverberate with each other. This study, which is one of the chapters of the unfinished book La machine d'Orvieto, was first published in French in Y voir mieux, y regarder de plus près (Rue d'Ulm, 2010).
The Troubles of the Neck
Authors: Krauss Rosalind E.
Published: March 2019

Rosalind E. Krauss discusses William Kentridge's The Head & the Load.
Surface Statistics of an Unknown Language Indicate How to Parse It
Authors: Wang Dingquan , Eisner Jason
Published: March 2019

We introduce a novel framework for delexicalized dependency parsing in a new language. We show that useful features of the target language can be extracted automatically from an unparsed corpus, which consists only of gold part-of-speech (POS) sequences. Providing these features to our neural parser enables it to parse sequences like those in the corpus. Strikingly, our system has no supervision in the target language. Rather, it is a multilingual system that is trained end-to-end on a variety of other languages, so it learns a feature extractor that works well. We show experimentally across multiple languages: (1) Features computed from the unparsed corpus improve parsing accuracy. (2) Including thousands of synthetic languages in the training yields further improvement. (3) Despite being computed from unparsed corpora, our learned task-specific features beat previous work’s interpretable typological features that require parsed corpora or expert categorization of the language. Our best method improved attachment scores on held-out test languages by an average of 5.6 percentage points over past work that does not inspect the unparsed data (McDonald et al., 2011), and by 20.7 points over past “grammar induction” work that does not use training languages (Naseem et al., 2010).
New species and new records of Copris (Coleoptera: Scarabaeidae: Scarabaeinae) from Mexico and the United States
Authors: MCCLEVE SCOTT , KOHLMANN BERT
Published: March 2019

One new species of Copris Geoffroy from Sonora and Chihuahua is described and illustrated: Copris warneri sp. nov. The new species is closely related to C. arizonensis Schaeffer. Drawings of the male and female and a distribution map are included. New distributional records for C. arizonensis Schaeffer and C. martinezi Matthews and Halffter are provided.
A taxonomic revision of Piezura Rondani (Diptera: Fanniidae)
Authors: MOORES AMY , SAVAG JADE
Published: March 2019

The world fauna of the genus Piezura Rondani is revised in order to resolve a series of long standing taxonomic errors. All species are redescribed, and species concepts and distribution ranges of most species have been modified. The genitalia of all species are illustrated and keys to each sex are provided. The female of P. nearctica Chillcott is described for the first time. Piezura pardalina shanxiensis Wang et al, 1992 is treated as an unavailable name, and P. pardalina shanxiensis Xue et al, 1999 is accepted as the valid name for this taxon.
Revision and phylogeny of the rare Priotomis Townes (Hymenoptera, Ichneumonidae, Cryptinae), with three new species and first description of the male
Authors: TEDESCO ANAZÉLIA M. , AGUIAR ALEXANDRE P.
Published: March 2019

Priotomis vinhai Tedesco, sp. nov., from the restingas of southeastern Brazil, P. echyrus Tedesco, sp. nov., from Mexico and Costa Rica, and Priotomis flammatus Tedesco, sp. nov., from Panama and Brazil, are described and illustrated. The monophyly of the genus and the relationships of its species were cladistically tested using implied weighting, in a matrix with 22 species, including four species of Priotomis, and 92 external structural characters. Concavity constants (K) from 1 to 6 were tested. All analyses recovered Priotomis as monophyletic. A redescription of Priotomis is presented, combining the original definition with original information, expanding the limits of the genus. All results indicate P. vinhai, sp. nov. as the basal-most species of the genus; all results with K=2–5 recovered the apical clade P. rana + (P. echyrus, sp. nov. + P. flammatus, sp. nov.). An updated key to species is presented. Additional distribution records are provided, expanding the known range of Priotomis to 41º11’ latitude degrees, from Mexico to Argentina.
Tentative key to robber fly (Diptera: Asilidae) subfamilies based on pupal cases
Authors: DENNIS D. STEVE , BARNES JEFFREY K.
Published: March 2019

Subfamily keys for pupal cases of Asilidae are currently based on 5 taxa, Asilinae, Dasypogoninae, Megapodinae, Laphriinae and Leptogastrinae. Analysis of recently published adult morphological data and DNA sequence data suggests that the family consists of 14 subfamilies. A tentative key based on known pupal cases is provided for 10 of these subfamilies: Asilinae, Brachyrhopalinae, Dasypogoninae, Dioctriinae, Laphriinae, Leptogastrinae, Ommatiinae, Stenopogoninae, Stichopogoninae and Willistonininae. It is difficult to distinguish between Brachyrhopalinae and Dasypogoninae pupal cases because so many characteristics overlap. There are no described pupal cases for 4 subfamilies: Bathypogoninae, Phellinae, Tillobromatinae and Trigonomiminae. Morphological data are available for only approximately 10% of the genera and 2% of the species of Asilidae.
Notes on winter flies Trichoceridae (Diptera) of Mongolia with description of new species ANDRIUS PETRAŠIŪNAS & SIGITAS PODĖNAS (Lithuania)
Authors: PETRAŠIŪNAS ANDRIUS , PODĖNAS SIGITAS
Published: March 2019

The family of winter flies Trichoceridae is newly recorded for Mongolia. Four species, Trichocera (Metatrichocera) gigantea (Dahl), T. (M.) mackenziei (Dahl), T. (Saltrichocera) regelationis (Linnaeus) and T. (Trichocera) hiemalis (De Geer) are first recorded in Mongolia from sampling during 1996, 2003–2006, 2008. A new species, Trichocera (Saltrichocera) chuluuta, is described from specimens collected during the fieldwork of the Mongolian Aquatic Insect Survey Project in western and north-central Mongolia.
The Little Lichen Dragon—an extraordinary katydid from the Ecuadorian Andes (Orthoptera, Tettigoniidae, Phaneropterinae, Dysoniini)
Authors: BRAUN HOLGER
Published: March 2019

Lichenodraculus matti gen. et sp. nov. is described, along with its conspicuous diurnal calling song and some aspects of its interesting ecology and life history. The song allowed a complete acoustic assessment of the altitudinal distribution of this otherwise very cryptic canopy-dwelling insect. The nymph perfectly mimics epiphytic lichens growing in the same elevation range, and apparently the downside of this camouflage is a strictly lichenous diet.
The ontogeny of morphological traits in three European species of Cosmochthonius Berlese, 1910 (Acari: Oribatida: Cosmochthoniidae)
Authors: SENICZAK STANISŁAW , PENTTINEN RITVA , SENICZAK ANNA
Published: March 2019

The morphology of juvenile stages and ontogeny of Cosmochthonius reticulatus Grandjean, 1947, C. foliatus Subías, 1982, and C. ugamaensis Gordeeva, 1980 are described and illustrated for the first time, and compared to the adults. Juveniles of these species differ mainly by the number of cilia on hypertrophied setae of e- and f-series, the shape of seta h 1 in the larva, and the shape of posterior gastronotal setae in nymphs. Cosmochthonius reticulatus has the fewest cilia on these setae, while the larva of C. ugamaensis and the nymphs and adult of C. foliatus have the most. In all species the number of cilia increases during ontogeny, more so in C. foliatus than in C. ugamaensis and C. reticulatus. Adults of these species differ mainly by the pattern of cerotegument and cuticle, best seen in SEM micrographs. Apparent in light microscopy the pygidium of C. reticulatus is reticulate, that of C. foliatus has rounded foveae, while that of C. ugamaensis has small circles and semicircles. The cuticle of the latter species is covered with thin, granular cerotegument, while that of the other species has thick, netlike cerotegument; C. foliatus also has a cerotegumental collar. Adults of all species differ also by the shape of posterior notogastral setae, and the location of some genital setae.
On the Calviriidae Martens and Curini-Galletti, 1993 (Platyhelminthes, Proseriata), with the description of three new species
Authors: SCHOCKAERT ERNEST R. , CURINI-GALLETTI MARCO , DE RIDDER WOUTER , ARTOIS TOM
Published: March 2019

Three new species of Calviriidae are described, belonging to two new genera: Diskeria gigantea n.g. n.sp., D. tasmanica n.sp. and Paracalviria islandica n.g. n.sp. The species of Diskeria have a copulatory organ with two rings of needles of which the internal ring forms a structure resembling a stylet. The accessory organ has a large glandular reservoir connected by a muscular duct to a “true” stylet surrounded by needles. The two species can be discerned by the number and size of the needles in the copulatory organ and in the accessory organ. In the female system there is a large terminal bursa. Paracalviria islandica has a copulatory organ with one circle of ±60 needles and an unarmed, sucker-like accessory organ in the male atrium. The female system is very simple without a bursa. Contrary to the other members of the Calviriidae, P. islandica has an epidermis with insunk nuclei, no septum in front of the pharynx and no sphincter around the gut above the pharynx. The relationships of and within the Calviriidae are discussed and compared with the recent results based on DNA analyses. Morphological arguments are given for the monophyly of the taxon Calviriidae. Amended diagnoses for the family and the four genera within the family are provided.
"Xenopus paratropicalis" is not a valid name
Authors: BLACKBURN DAVID C. , BEIER MANFRED
Published: March 2019

Mechkarska et al. (2011) recently provided an analysis of antimicrobial peptides in two species in the frog family Pipidae — Xenopus andrei and “Silurana paratropicalis”. We provide a review of the species associated with the latter taxon name and argue that this is not a valid name.
Phylogenetic position of Dendropsophus gaucheri (Lescure and Marty 2000) highlights the need for an in-depth investigation of the phylogenetic relationships of Dendropsophus (Anura: Hylidae)
Authors: FOUQUET ANTOINE , NOONAN BRICE P. , BLANC MICHEL , ORRICO VICTOR GOYANNES DILL
Published: March 2019

Dendropsophus gaucheri is a recently described species which inhabits open areas of the eastern part of the Guiana Shield and is currently assigned to the D. parviceps species group based on the presence of a subocular cream spot. Herein we investigate its phylogenetic position including material from the type locality and newly documented populations from Suriname and Brazil based on mtDNA sequences. The species, as well as D. riveroi which is assigned to the D. minimus species group, were recovered nested within the D. microcephalus species group which implies the paraphyly of the three Dendropsophus species groups. Such result, along with other evidences, highlights the need for a thorough revision of the genus. The genetic distances among D. gaucheri samples studied are low confirming their conspecificity and suggesting recent connections among populations from open areas currently isolated by rainforest in the lowlands of the Guiana Shield.
Two new species of the deep-sea squat lobster genus Munida Leach, 1820 (Crustacea: Decapoda: Munididae) from Taiwan: morphological and molecular evidence
Authors: CABEZAS PATRICIA , LIN CHIA-WEI , CHAN TIN-YAM
Published: March 2019

The genus Munida Leach, 1820 is the most diverse group within the squat lobsters, with approximately 250 described species. The extreme morphological similarity among certain species makes very difficult to identify diagnostic characters, and the real diversity of the group is probably underestimated. Here, two new species of the genus Munida from Taiwan previously identified as M. distiza Macpherson, 1994 and M. militaris Henderson, 1885, respectively, are described and illustrated. The two species are identified by subtle and constant morphological differences, which match clear molecular divergences in the 16S and COI genes. These results confirm the taxonomic value of slight morphological differences, and emphasize the need for more detailed analysis to clarify the phylogenetic relationships within the genus.
Review of the genus Microphilypnus Myers, 1927 (Teleostei: Gobioidei: Eleotridae) from the lower Amazon basin, with description of one new species
Authors: CAIRES RODRIGO A. , DE FIGUEIREDO JOSÉ LIMA
Published: March 2019

Microphilypnus Myers, 1927 is a genus with three nominal species (M. amazonicus and M. macrostoma from the lower Amazon basin, and M. ternetzi from Orinoco), and is among the most poorly studied groups of Neotropical fishes. In this paper, M. ternetzi and M. macrostoma are redescribed and validated and M. amazonicus is regarded as synonym of M. ternetzi. Also, a new species, M. acangaquara, is described from the lower Amazon.
Pseudeutropius indigens, a new species of schilbeid catfish (Teleostei: Siluriformes) from peninsular Thailand
Authors: NG HEOK HEE , VIDTHAYANON CHAVALIT
Published: March 2019

Pseudeutropius indigens, a new species of schilbeid catfish from peninsular Thailand, is described here. It can be distinguished from congeners in having the following combination of characters: head length 23.1–24.3% SL, head width 10.5– 11.0% SL, length of anal-fin base 45.6–50.4% SL, 37–41 anal-fin rays, isognathous jaws in which the premaxillary teeth are not visible when the mouth is closed, and long nasal, maxillary and mandibular barbels that reach to at least the analfin origin.
Revision of the genus Paraplaneta Warren, 1895 (Lepidoptera: Geometridae, Larentiinae) from Southeast Asia
Authors: CHOI SEI-WOONG , STÜNING DIETER
Published: March 2019

The genus Paraplaneta Warren, 1895, until recently treated as a junior synonym of Cataclysme Hübner [1825], is revised. Both genera are members of the tribe Cataclysmini (Herbulot, 1962–63). As a whole, eight species of Paraplaneta are recognized from Himalaya region (India, Pakistan) and China, including four new species: P. anthracica, P. griseobrunnea, P. subfasciata (from China), and P. hreblayi (from Pakistan), described herein. A lectotype for Cataclysme conturbata sternecki Prout, 1938 is designated. Descriptions, diagnoses and illustrations of antennae, wing venation and male and female genitalia of most species are given. The tribal placement of Paraplaneta and related genera within the Cataclysmini is discussed.
A new species of Paramaka Savage & Domínguez, 1992 (Ephemeroptera: Leptophlebiidae: Atalophlebiinae) from Brazil
Authors: MARIANO RODOLFO
Published: March 2019

A new species of Paramaka is described based on nymphs and male imagos from State of Mato Grosso, Brazil. The imago of Paramaka pearljam sp. n. can be easily separated from the other species of the genus by the presence of a conspicuous and large median projection with apex curved ventrally on styliger plate; and in nymph by the gills not ended in a thin apical process and tarsal claw without accessory denticles. A new key is proposed and new geographic records for the genus are reported.
The Rheumatobates Bergroth, 1892 (Hemiptera: Heteroptera: Gerridae) of Colombia, including the description of R. plumipes n. sp. and a key to represented species
Authors: CASTRO-VARGAS MARIA I. , MORALES-CASTAÑO IRINA T.
Published: March 2019

Nine species of Rheumatobates are recorded from Colombia. Rheumatobates plumipes n. sp. is described. New departamental records are presented for R. imitator (Córdoba) and R. crassifemur crassifemur (Caquetá), and the geographical range of R. clanis is expanded to Colombia. The general habitus of males and females is illustrated. A key for the species of the genus found in Colombia is also provided.
A new species of Alloperla (Plecoptera: Chloroperlidae) from China
Authors: LI WEIHAI , WANG RONGFENG
Published: March 2019

A chloroperline stonefly species from Liaoning Province, northeastern China is described as new to science: Alloperla yangi sp. n. Its taxonomic relationship to similar species is discussed.
The genus Micandra Staudinger (Lepidoptera: Lycaenidae: Theclinae) in Colombia, with the description of a new species from the Sierra Nevada de Santa Marta
Authors: PRIETO CARLOS
Published: March 2019

Micandra stephanieae, sp. nov., is described and illustrated from the Sierra Nevada de Santa Marta in northern Colombia. Adult specimens and male genitalia are illustrated and compared with those of M. aegides (C. Felder & R. Felder) and M. dignota (Draudt), the putatively most closely related species. A synopsis of the Micandra species in Colombia is presented along with distribution maps and a key to the species based on wing pattern.
Six new species and three new records of infaunal alpheid shrimps from the genera Leptalpheus Williams, 1965 and Fenneralpheus Felder & Manning, 1986 (Crustacea, Decapoda)
Authors: ANKER ARTHUR
Published: March 2019

Several species of the infaunal alpheid genera Leptalpheus Williams, 1965 and Fenneralpheus Felder & Manning, 1986 are described as new or reported from new localities in the tropical western Atlantic and eastern Pacific. In the genus Leptalpheus, five species are described as new: L. marginalis sp. nov. from the Caribbean coast of Colombia; L. penicillatus sp. nov. from the Pacific coast of Panama and Costa Rica; L. azuero sp. nov., L. hendrickxi sp. nov., and L. bicristatus sp. nov., all three from the Pacific coast of Panama. In addition, L. cf. forceps Williams, 1965 and L. felderi Anker, Vera Caripe & Lira, 2006 are reported for the first time from the Caribbean coast of Panama. Several unidentified species of Leptalpheus presently known from incomplete or immature specimens are also reported. In the genus Fenneralpheus, F. orabovis sp. nov. is described as new, whereas F. chacei Felder & Manning, 1986 is reported from the Caribbean coast of Panama, representing the first finding of this species outside its type locality in Florida. The generic diagnoses of both Leptalpheus and Fenneralpheus are emended to accommodate the new species.
First record of Symphyla (Myriapoda) from Iran, with description of a new species in Scolopendrellopsis (Scolopendrellidae)
Authors: SCHELLER ULF , KAVIANPOUR MOHAMMAD REZA , ESFANDIARI MEHDI
Published: March 2019

The first species of Symphyla was described in 1763 and many hundreds of papers on the group have since appeared with almost 200 species having been described. However, very few of them deal with material from Asia (Scheller, 1971, 1988, Scheller & Golovatch, 1982, Scheller & Mikhaljova, 2000) and not a single species has been recorded from Iran. Now one of us (M.R. Kavianpour) has collected them for the first time from there. They appeared in a study of soil-living mites in gardens with pomegranates and grapes in the vicinity of Shahreza in the Esfahan Province, about 500 km south of Teheran, 1800 m asl., and were obtained from Berlese extractions of soil samples down to a depth of 20–30 cm.
Calappa exanthematosa Alcock & Anderson, 1894, as a valid species of box crab from the Indian Ocean (Crustacea: Decapoda: Calappidae)
Authors: NG PETER K. L. , LAI JOELLE C. Y. , GHOTBEDDIN NEGAR , SAFAIE MOHSEN
Published: March 2019

The box crab Calappa exanthematosa Alcock & Anderson, 1894, originally described from the Bay of Bengal, has been synonymised under C. japonica Ortmann, 1892 (type locality Japan), since 1937. Comparisons of specimens from the Gulf of Oman and India reveal consistent differences in the live colour of material from the rest of the Indo-West Pacific region, carapace (general form, shape of lateral teeth, position of longitudinal gastro-cardiac grooves, structures of posterior region), pterygostomian lobe, chela, male abdominal somite 6, male telson and G1. Calappa exanthematosa is here recognised as a distinct species, redescribed, and illustrated.
New eriophyoid mites (Acari: Prostigmata: Eriophyoidea) from banana and heliconia in Northeastern Brazil—two new genera and three new species
Authors: REIS ALEUNY C. , GONDIM JR. MANOEL G. C. , NAVIA DENISE , FLECHTMANN CARLOS H. W.
Published: March 2019

A new genus and new species of the mite family Eriophyidae (Phyllocoptinae), namely Cothrix erugata n. sp. et n. gen., is described from Heliconia stricta Huber (Heliconiaceae). In addition, one new genus and two new species of Diptilomiopidae, namely Rhyncadicrus asperulus n. sp. et n. gen. from banana, Musa acuminata Colla x Musa balbisiana Colla (genomic group AAB) (Musaceae) and Catarhinus granatus n. sp. from Heliconia bihai L., are described and illustrated. The mites were collected in the State of Pernambuco, Northeastern Brazil. All were vagrants on the lower leaf surfaces of their host plants and no visible damage symptoms were observed.
Amphisbaena uroxena Mott, Rodrigues, De Freitas and Silva 2008 (Squamata, Amphisbaenidae) shows sexual dimorphism in precloacal pores
Authors: MOTT TAMÍ , RODRIGUES MIGUEL TREFAUT , DE FREITAS MARCO ANTÔNIO
Published: March 2019

In 2008, Mott, Rodrigues, De Freitas and Silva (Journal of Herpetology 42: 172) described as a new species Amphisbaena uroxena, characterized among other features by the presence of conic tubercles concentrated in a circle on the dorsal surface of the tail, an unique feature among South American amphisbaenids. At that time, based only on the three specimens of the type series, all without precloacal pores, they speculated that the absence of pores could be a sex-based difference. In fact, in other amphisbaenid species, the absence of pores in females has been either reported (A. dubia and A. heathi, Vanzolini 2002; A.hiata, Montero & Céspedez 2002) or noticed (A. anaemariae, observed by TM).
Mantodea of Egypt
Authors: MOHAMMAD SALWA KAMAL , ALLA SOHAIR MOHAMMAD GAD , EL-HAMOULY HAYAM , EHRMANN REINHARD , NASSER MOHAMED GEMAL EL-DEN
Published: March 2019

The Mantodea of Egypt were studied by examining and identifying specimens from four main Egyptian collections and some of those preserved in international museums, collecting specimens from various parts of the country between July 2007 and April 2010, and previous Egyptian records. We found 60 species belonging to 21 genera and 4 families. Eremiaphilidae included 31 species in 2 genera with one new record from Egypt, Eremiaphila gigas; Empusidae, 7 species in 4 genera; Mantidae, 18 species in 13 genera with one new species, Elaea solimani; and Tarachodidae, 3 species in 2 genera. We provide identification keys for Egyptian taxa, data on the material examined, the world distribution, synonyms and a description of the new species.