bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluating Against a Multi-Dimensional Economic Goal: A Sustainable and Prosperous Socialism
Authors: Campbell Al
Published: May 2021

The concept of evaluation of any existing or proposed policy only has meaning in relation to some goal. Further, if the goal used for the evaluation is not the actual goal of the actor involved, any conclusions about the effectiveness or appropriateness of the policies are irrelevant for that actor. It is very common for people around the world to evaluate the economic policies of Cuba relative to claimed effects on the rate of growth of Gross Domestic product (GDp), followed by discussions on what the real effect on the GDp of the policies has been or will be. Given that Cuba has very explicitly stated that its economic goal is a prosperous, sustainable socialism, such considerations cannot constitute economic evaluations of policies for the country. A proper evaluation is, however, complicated by the multi-dimensional nature of the Island’s economic goal. This article considers six of Cuba’s most fundamental and commonly discussed economic policies as examples, to argue that in practice it is very often, though not necessarily always, possible to design policies in such a way that their evaluation relative to all the dimensions of Cuba’s economic goal does not involve the potential problem of the “trade-off between dimensions” inherent to any multi-dimensional goal.
Four-direction global matching with cost volume update for stereovision
Authors: Jin Yusheng , Zhao Hong , Bu Penghui
Published: May 2021

The accuracy and speed of semi-global matching (SGM) make it widely used in many computer vision problems. However, SGM often struggles in dealing with pixels in the homogeneous regions and also suffers from streak artefacts for weak smoothness constraints. Meanwhile, we observe that the global method usually fails in occluded areas. The disparities for occluded pixels are typically the average of the disparity of nearby pixels. The local method can propagate the information into occluded pixels with a similar color. In this paper, we propose a novel, to the best of our knowledge, four-direction global matching with a cost volume update scheme to cope with textureless regions and occlusion. The proposed method makes two changes in the recursive formula: a) the computation process considers four visited nodes to enforce more smooth constraints; b) the recursive formula integrates cost filtering to propagate reliable information farther in nontextured regions. Thus, our method can inherit the speed of SGM, properly avoid streaking artefacts, and deal with the occluded pixel. Extensive experiments in stereo matching on Middlebury demonstrate that our method outperforms typical SGM-based cost aggregation approaches and other state-of-the-art local methods.
Achromatic photonic tricouplers for application in nulling interferometry
Authors: Martinod Marc-Antoine , Tuthill Peter , Gross Simon , Norris Barnaby , Sweeney David , Withford Michael J.
Published: May 2021

Integrated-optic components are being increasingly used in astrophysics, mainly where accuracy and precision are paramount. One such emerging technology is nulling interferometry that targets high contrast and high angular resolution. Two of the most critical limitations encountered by nullers are rapid phase fluctuations in the incoming light causing instability in the interference and chromaticity of the directional couplers that prevent a deep broadband interferometric null. We explore the use of a tricoupler designed by ultrafast laser inscription that solves both issues. Simulations of a tricoupler, incorporated into a nuller, result in an order of a magnitude improvement in null depth.
Space curvature-inspired nanoplasmonic sensor for breast cancer extracellular vesicle fingerprinting and machine learning classification
Authors: Kazemzadeh Mohammadrahim , Hisey Colin L. , Artuyants Anastasiia , Blenkiron Cherie , Chamley Lawrence W. , Zargar-Shoshtari Kamran , Xu Weiliang , Broderick Neil G. R.
Published: May 2021

Extracellular vesicles (EVs) are micro and nanoscale lipid-enclosed packages that have shown potential as liquid biopsy targets for cancer because their structure and contents reflect their cell of origin. However, progress towards the clinical applications of EVs has been hindered due to the low abundance of disease-specific EVs compared to EVs from healthy cells; such applications thus require highly sensitive and adaptable characterization tools. To address this obstacle, we designed and fabricated a novel space curvature-inspired surfaced-enhanced Raman spectroscopy (SERS) substrate and tested its capabilities using bioreactor-produced and size exclusion chromatography-purified breast cancer EVs of three different subtypes. Our findings demonstrate the platform’s ability to effectively fingerprint and efficiently classify, for the first time, three distinct subtypes of breast cancer EVs following the application of machine learning algorithms on the acquired spectra. This platform and characterization approach will enhance the viability of EVs and nanoplasmonic sensors towards clinical utility for breast cancer and many other applications to improve human health.
Depth-recognizable time-domain fluorescence molecular tomography in reflective geometry
Authors: Cheng Jiaju , Zhang Peng , Cai Chuangjian , Gao Yang , Liu Jie , Hui Hui , Tian Jie , Luo Jianwen
Published: May 2021

Conventional fluorescence molecular tomography (FMT) reconstruction requires photons penetrating the whole object, which limits its applications to small animals. However, by utilizing reflective photons, fluorescence distribution near the surface could be reconstructed regardless of the object size, which may extend the applications of FMT to surgical navigation and so on. Therefore, time-domain reflective fluorescence molecular tomography (TD-rFMT) is proposed in this paper. The system excites and detects the emission light from the same angle within a field of view of 5 cm. Because the detected intensities of targets depend strongly on the depth, the reconstruction of targets in deep regions would be evidently affected. Therefore, a fluorescence yield reconstruction method with depth regularization and a weighted separation reconstruction strategy for lifetime are developed to enhance the performance for deep targets. Through simulations and phantom experiments, TD-rFMT is proved capable of reconstructing fluorescence distribution within a 2.5-cm depth with accurate reconstructed yield, lifetime, and target position(s).
Overcoming constraints of scaling: Critical and empirical perspectives on agricultural innovation scaling
Authors: Gebreyes Million , Mekonnen Kindu , Thorne Peter , Derseh Melkamu , Adie Aberra , Mulema Annet , Kemal Seid Ahmed , Tamene Lulseged , Amede Tilahun , Haileslassie Amare , Gebrekirstos Aster , Mupangwa Walter Tamuka , Ebrahim Mohammed , Alene Temesgen , Asfaw Addisu , Dubale Workneh , Yasabu Simret
Published: May 2021

Scaling is a ubiquitous concept in agricultural research in the global south as donors require their research grantees to prove that their results can be scaled to impact upon the livelihoods of a large number of beneficiaries. Recent studies on scaling have brought critical perspectives to the rather technocratic tendencies in the agricultural innovations scaling literature. Drawing on theoretical debates on spatial strategies and practical experience of agricultural innovation scaling in Ethiopia, this paper adds to the current debate on what constitutes scaling and how to overcome critical scaling constraints. The data for the paper came from a qualitative assessment using focus group discussions, key informant interviews, and document analysis on scaling work done in Ethiopia by a USAID-funded research for development project. The paper concludes with four broad lessons for the current understating of agricultural innovation scaling. First, scaling of agricultural innovations requires a balanced focus on technical requirements and associated social dynamics surrounding scaling targets, actors involved and their social relations. Second, appreciating the social dynamics of scaling emphasizes the fact that scaling is more complex than a linear rolling out of innovations towards diffusion. Third, scaling may not be strictly planned; instead, it might be an extension of the innovation generation process that relies heavily on both new and long-term relationships with key partners, trust, and continuous reflection and learning. Fourth, the overall implication of the above three conclusions is that scaling strategies need to be flexible, stepwise, and reflective. Despite the promises of flourishing scaling frameworks, scaling strategies it would appear from the Africa RISING experience that, if real impact is to be achieved, approaches will be required to be flexible enough to manage the social, processual and emergent nature of the practice of scaling.
Knockdown of hsa_circ_0001275 reverses dexamethasone-induced osteoblast growth inhibition via mediation of miR-377/CDKN1B axis
Authors: Xu Yan , Sun Liqin , Hu Juncheng , Xu Sai
Published: May 2021

Background

Osteoporosis affects the quality of life among middle-aged and elderly individuals. In addition, dysfunction of osteoblasts can lead to the progression of osteoporosis. Circular (circ)RNAs are involved in various types of diseases, including osteoporosis. Moreover, it has been reported that hsa_circ_0001275 expression is upregulated in osteoporosis. However, the effects of hsa_circ_0001275 on the growth of osteoblasts remain unclear.

Methods

In the present study, the gene and protein expression levels in hFOB1.19 cells were detected via reverse transcription-quantitative (RT-qPCR) and western blot analyses, respectively. In addition, alkaline phosphatase (ALP) activity and calcium nodules were examined by ALP and alizarin red staining, respectively. Cell proliferation was measured using the Cell Counting Kit-8 assay. Cell apoptosis and cell cycle were analyzed by flow cytometry. Furthermore, dual luciferase reporter and RNA pull-down assay were used to confirm the association among hsa_circ_0001275, microRNA (miR)-377 and CDKN1B.

Results

DEX-induced hFOB1.19 cell growth inhibition was significantly reversed by silencing hsa_circ_0001275. Moreover, DEX significantly increased ALP activity and calcium nodules in hFOB1.19 cells, while this effect was significantly reversed in the presence of hsa_circ_0001275 small interfering RNA. In addition, miR-377 was sponged by hsa_circ_0001275 and CDKN1B was directly targeted by miR-377 in hFOB1.19 cells. Furthermore, the therapeutic effect of hsa_circ_0001275 knockdown on osteoporosis was notably reversed by miR-377 antagomir.

Conclusion

The data demonstrated that knockdown of hsa_circ_0001275 reversed DEX-induced osteoblast growth inhibition via activation of the miR-377/CDKN1B axis. Therefore, this study might shed new lights on the treatment of osteoporosis.
Comparative proteomic analysis to annotate the structural and functional association of the hypothetical proteins of S. maltophilia k279a and predict potential T and B cell targets for vaccination
Authors: Ezaj Md. Muzahid Ahmed , Haque Md. Sajedul , Syed Shifath Bin , Khan Md. Shakil Ahmed , Ahmed Kazi Rejvee , Khatun Mst. Tania , Nayeem S. M. Abdul , Rizvi Golam Rosul , Al-Forkan Mohammad , Khaleda Laila
Published: May 2021

Stenotrophomonas maltophiliais a multidrug-resistant bacterium with no precise clinical treatment. This bacterium can be a vital cause for death and different organ failures in immune-compromised, immune-competent, and long-time hospitalized patients. Extensive quorum sensing capability has become a challenge to develop new drugs against this pathogen. Moreover, the organism possesses about 789 proteins which function, structure, and pathogenesis remain obscured. In this piece of work, we tried to enlighten the aforementioned sectors using highly reliable bioinformatics tools validated by the scientific community. At first, the whole proteome sequence of the organism was retrieved and stored. Then we separated the hypothetical proteins and searched for the conserved domain with a high confidence level and multi-server validation, which resulted in 24 such proteins. Furthermore, all of their physical and chemical characterizations were performed, such as theoretical isoelectric point, molecular weight, GRAVY value, and many more. Besides, the subcellular localization, protein-protein interactions, functional motifs, 3D structures, antigenicity, and virulence factors were also evaluated. As an extension of this work, ’RTFAMSSER’ and ’PAAPQPSAS’ were predicted as potential T and B cell epitopes, respectively. We hope our findings will help in better understating the pathogenesis and smoothen the way to the cure.
Lung function and peak oxygen uptake in chronic obstructive pulmonary disease phenotypes with and without emphysema
Authors: Rasch-Halvorsen Øystein , Hassel Erlend , Brumpton Ben M. , Jenssen Haldor , Spruit Martijn A. , Langhammer Arnulf , Steinshamn Sigurd
Published: May 2021

Previous studies of associations of forced expiratory lung volume in one second (FEV1) with peak oxygen uptake (VO2peak) in chronic obstructive pulmonary disease (COPD) have not taken sex, age and height related variance of dynamic lung volumes into account. Nor have such demographic spread of spirometric measures been considered in studies comparing VO2peak between COPD phenotypes characterized by degree of emphysema. We aimed to assess the association of FEV1Z-score with VO2peak in COPD (n = 186) and investigate whether this association differs between emphysema (E-COPD) and non-emphysema (NE-COPD) phenotypes. Corresponding assessments using standardized percent predicted FEV1 (ppFEV1) were performed for comparison. Additionally, phenotype related differences in VO2peak were compared using FEV1Z-score and ppFEV1 as alternative expressions of FEV1. E-COPD and NE-COPD were defined by transfer factor of the lung for carbon monoxide below and above lower limits of normal (LLN), respectively. The associations were assessed in linear regression models. One unit reduction in FEV1Z-score was associated with 1.9 (95% CI 1.4, 2.5) ml/kg/min lower VO2peak. In stratified analyses, corresponding estimates were 2.2 (95% CI 1.4, 2.9) and 1.2 (95% CI 0.2, 2.2) ml/kg/min lower VO2peak in E-COPD and NE-COPD, respectively. The association did not differ statistically by COPD phenotype (p-value for interaction = 0.153). Similar estimates were obtained in analyses using standardized ppFEV1. Compared to NE-COPD, VO2peak was 2.2 (95% CI 0.8, 3.6) and 2.1 (95% CI 0.8, 3.5) ml/kg/min lower in E-COPD when adjusted for FEV1Z-score and ppFEV1, respectively. In COPD, FEV1Z-score is positively associated with VO2peak. This association was stronger in E-COPD but did not differ statistically by phenotype. Both the association of FEV1 with VO2peak and the difference in VO2peak comparing COPD phenotypes seems independent of sex, age and height related variance in FEV1. Mechanisms leading to reduction in FEV1 may contribute to lower VO2peak in E-COPD.
Big Five Personality Model-based study of death coping self-efficacy in clinical nurses: A cross-sectional survey
Authors: Lin Xi , Li Xiaoqing , Liu Qing , Shao Shengwen , Xiang Weilan
Published: May 2021

Background

Specific personality traits may affect the ability of nurses to deal with patient death. The relationship between personality and death coping self-efficacy (DCS) has rarely been investigated in the palliative care setting. In this study, we explored the associations between different personality profiles and DCS in clinical nurses from general wards and ICU.

Methods

A cross-sectional survey of 572 Chinese nurses was conducted between August and September 2020, by way of a self-administered questionnaire.

Results

Among the Big Five Personality Traits, in nurses the score was highest for conscientiousness and lowest for neuroticism. With regard to DCS, nurses scored highly on the intention of hospice care. The Big Five Personality Traits were found to explain 20.2% of the overall variation in DCS. Openness, agreeableness and conscientiousness were significantly associated with DCS in nurses.

Conclusions

Nursing managers should pay attention to differences in personality characteristics and provide personalized and targeted nursing education. This should improve nurses’ DCS, enrich their professional development and promote high quality palliative care for patients and their families.
Mundane ideologies of (in)hospitality: A guided coach tour
Authors: Lynch Paul
Published: May 2021

This article explores impressions of welcome and non-welcome in relation to a guided day tour in mainland China. The study is contextualized with regard to hospitality as ethics and tourism as a stage where the struggle for hegemonic ideology occurs. It focuses upon the author’s cognitive and emotional reception of the guides’ narratives and explores the mundane ideologies of (in)hospitality present drawing upon analysis of autoethnographic notes captured through sociological impressionism. Elements of the narrative sustaining the (in)hospitality discourse are identified. The tour serves as an embodiment of national hospitality and the guide as an ideology refractor. Ideological hospitality is one of the conditioning elements embedded in the hospitality interaction. Consideration is given to how tours might be ‘rehumanized’ through a social justice and equity guiding philosophy and education. In so doing, the study contributes to discussion regarding the possibilities of a hospitable society.
Deaf voices / Deaf art: Vocality through and beyond sound and sign1
Authors: Panopoulos Panayotis
Published: May 2021

Do we have a voice if we don’t speak a language? How does the voice of a sign language look like? What do we learn about vocality when we turn our ears and eyes towards deaf voices and the sign languages of the deaf? How can you make others hear the voice of a ‘silent’ minority? And what about ventriloquism, vocal interiority and acousmatic voice in the case of the deaf? By focusing mainly on the ways of the deaf with voice, especially as they materialize in the work of deaf artists using sound as the main material of their art-making, in this article I approach the significance of deaf vocalities for a wider understanding and experience of sound and voice for both the deaf and the hearing. The work of deaf artists working with sound and voice is an acoustic, vibratory, interpretive and activist lens through which we can get parallax views of our common assumptions about the vocal and listen to modulated renderings of our common conceptions of vocality. Through their investigations of the vocal and the sonic, deaf artists explore the deep roots of the metaphorical and symbolic valence of the vocal trope, while they steadily argue for alternative voices, non-acoustic, vibrational sonorities, through sign, motion, space, contact. Their experimental works unravel the experiential, metaphorical and theoretical facets of voice and sound, while they also project vocality onto other modes of communication and sociality, mainly sign and embodied ways of physical movement, thus extending the notion of voice to include sign languages and non-vocal communication. Deaf voices reveal a whole new field of questions on voice and agency, through and beyond sound and sign.
Das Lernen in Organisationen
Authors: Mbah Melanie , Brohmann Bettina
Published: May 2021

Transformationen und Verfahren, die über lange Zeiträume - über Generationen hinweg - andauern, stellen besondere Anforderungen an institutionelles bzw. organisationales Lernen. Institutionen müssen auf veränderte gesellschaftliche Rahmenbedingungen reagieren und neue Informationen und Wissensbestände in Entscheidungsprozessen berücksichtigen. Transformationen weisen spezifische Kennzeichen auf und stellen damit spezifische Managementanforderungen an Institutionen, um anpassungsfähig und flexibel zu sein. Hierzu braucht es die Bereitschaft und Offenheit, Neues aufzunehmen, um Kritik und insbesondere Fehler konstruktiv zu bearbeiten. Des Weiteren braucht es Räume und Formate, die ein Lernen auf verschiedenen Ebenen - des Individuums, des Kollektivs (eine Institution) und zwischen Kollektiven (mehreren Institutionen) - begünstigen, und Anstöße zum Lernen geben. Ausgehend von Transformationen und deren Kennzeichen werden im vorliegenden Beitrag spezifische Managementanforderungen abgeleitet und auf transformative Langzeit-Verfahren am Beispiel der Entsorgung hochradioaktiver Abfälle übertragen. Hierbei werden Konzepte des organisationalen Lernens diskutiert, unter Berücksichtigung von Change Management Ansätzen und spezifischen Voraussetzungen für das Lernen zwischen Organisationen. Das Standortauswahlverfahren und dessen Akteure werden hierbei beispielhaft
Design of Double Barrier Ceramic Radio Frequency Vacuum Window
Authors: Jha Akhil , Ajesh P. , Anand Rohit , Vasava Paresh Kumar , Trivedi Rajesh , Mukherjee Aparajita
Published: May 2021

Vacuum windows are an essential part of any radio frequency (RF) system which launches/couples RF power from an atmospheric to a vacuum environment. This paper describes the RF design of a double barrier ceramic coaxial vacuum window. Alumina 99.5% pure is considered as ceramic barrier material while inner and outer conductors are oxygen-free copper. As the initial design approach the thickness, slope, depth of ceramic in the conductor is varied and the performance of the window is studied. The design is optimised to achieve the best insertion loss, return loss response for operating frequency range up to 65MHz.
Design and Development of High Power Broad Band Dry RF Load
Authors: Nayek Narugopal , Naik Arvind , Phatangare Manoj , Tiwari T.
Published: May 2021

High power S-Band ferrite based RF load is designed and developed which is capable of handling 3 kW average power at operating frequency 2998±20 MHz . Electrical and thermal design is carried out using CST Studio Suite. Mechanical parts are fabricated according to the design. Water cooling is provided to the absorbing ferrites to support high power operation. Various RF load parts are fabricated, chemically cleaned and brazed. The experimental return loss better than 30 dB for a bandwidth of 250 MHz is achieved. The numerical and experimental results are discussed and presented in this paper.
Microwave Absorbing Materials
Authors: Singh Dharmendra
Published: May 2021

The 4th Prof. Vijaya Agarwala Memorial National Symposium on Microwave Absorbing Materials (VAMMAM-2020)” was held during 23 - 24th, August 2020 at Indian Institute of Technology Roorkee in association with Centre of Nanotechnology and Common Research Technology Development Hub (CRTDH) for New Materials/Stealth Applications and Department of Applied Mechanics Motilal Nehru National Institute of Technology Allahabad, Prayagraj, India.
Перевоспитать нельзя наказывать? Как конструируются сценарии реинтеграции и ресоциализации «трудных» подростков
Authors: Лисовская Ирина Викторовна
Published: May 2021

В статье описывается применение сценарного подхода к анализу процессов ресоциализации и реинтеграции «трудных» подростков, воспитывающихся в социально-поддерживающих организациях. В качестве исследовательской стратегии используется кейс-стади, детально изучаются четыре случая (учреждения) с использованием методов: полуструктурированного интервью с подростками (n = 29); экспертного интервью с работниками социально-поддерживающих организаций (n = 11); включенного наблюдения и анализа документов. Отвечая на исследовательский вопрос, какие существуют сценарии реинтеграции и ресоциализации «трудных» подростков, и каким образом они конструируются, автор выделяет группы образующих и частных критериев. Приводится пять сценариев: «слияния», «выхода за рамки», «подчинения режиму», «беглеца» и «изоляции», которые отображают ситуативные модели поведения подростков, воспитывающихся в социально-поддерживающих организациях; трансформацию опыта социальной группы под воздействием институционального дизайна организации; режимов взаимоотношений между работниками и воспитанниками; различных частных особенностей случаев. В статье также анализируются возможности сценарного подхода — его достоинства и недостатки.
Благодарность. Выражаю благодарность моей научной руководительнице Омельченко Елене, внесшей огромный вклад в кандидатскую диссертацию (защищена в январе 2019 г), по материалам которой написана эта статья, обобщающая ключевые выводы. Также большая благодарность всем организациям, принявшим участие в исследовании, всем неравнодушным проводникам, информантам, согласившимся на интервью, а также моему со-интервьюеру в одном из кейсов — Багуриной Ольге.
Professional written voice “in flux”: the case of social work
Authors: Lillis Theresa
Published: May 2021

Contemporary professional social work can be characterised by increased textualisation (after Iedema and Scheeres 2003) with written texts mediating most action. At the same time, writing, as a key dimension to social workers’ practice and labour, is often institutionally unacknowledged, becoming visible primarily when identified as a “problem.” This paper draws on a three year nationally funded UK-based research project to offer a situated account of contemporary professional social work writing, challenging dominant institutional orientations to writing in professional practice. The paper outlines the specific ways in which social work practices, including writing, can be characterised as being ‘in flux’. Drawing on ethnographic data and adopting a  Bakhtinian (1981, 1986) oriented approach to voice, the paper explores the entextualisation of three specific social work texts, focusing in particular on critical moments (after Candlin 1987, 1997). These critical moments offer insights into key problematics of social work writing, in particular the tensions around professional voice and discourse. The paper concludes by arguing for an articulation of professional social work writing which takes account of the dialogic nature of language and the discoursal challenges experienced in everyday practice.
What About Realism? Alberto Blest Gana, Georg Lukács, and Their Chilean Readers
Authors: Patruno Luigi
Published: May 2021

In this article, I analyse Georg Lukács’s theories of realism in relation to Alberto Blest Gana’s work. For this purpose, I explore two essays that have greatly contributed to locating the Chilean author’s novels within the realm of literary realism. The texts chosen for my study are Jaime Concha’s prologue to the Martín Rivas edition by the Ayacucho Library and Ricardo A. Latcham’s essay “Blest Gana y la novela realista” [Blest Gana and the Realist Novel]. Concha and Latcham find appropriate categories for the interpretation of Blest Gana’s work in Lukács’s essays. In their readings, they accurately apply notions such as the selective principle or the typology of characters. However, while using those insights as a shared critical platform, they arrive at different interpretations of what is meant by realism. The article elucidates the role played by Concha and Latcham in the Chilean intellectual field and shows how literary genealogies inform their critical projects.
Basic Issues of Cultural Interaction: A European Perspective
Authors: Rüsen Jörn
Published: May 2021

The paper concentrates on the issue of ethnocentrism in cultural interaction. It briefly mentions the East Asian case and mainly tackles the European one. It gives examples of ethnocentric attitudes in history, but its main point is presenting examples of overcoming the unbalanced evaluation in expressing cultural identity and difference by means of new forms of generating a sense of history. Examples are discussed as indicators of new approaches to dealing with morality beyond the highly problematic distinction between good and evil along the line of self and other.
Partial sums and inclusion relations for analytic functions involving (p, q)-differential operator
Authors: Tang Huo , Vijaya Kaliappan , Murugusundaramoorthy Gangadharan , Sivasubramanian Srikandan
Published: May 2021

Let

f

k

(

z

)

=
z
+

∑

n
=
2

k

a

n

z

n

{f}_{k}\left(z)=z+{\sum }_{n=2}^{k}{a}_{n}{z}^{n}

be the sequence of partial sums of the analytic function

f

(

z

)

=
z
+

∑

n
=
2

∞

a

n

z

n

f\left(z)=z+{\sum }_{n=2}^{\infty }{a}_{n}{z}^{n}

. In this paper, we determine sharp lower bounds for

Re

{

f

(

z

)

/

f

k

(

z

)

}

{\rm{Re}}\{f\left(z)\hspace{-0.08em}\text{/}\hspace{-0.08em}{f}_{k}\left(z)\}

,

Re

{

f

k

(

z

)

/

f

(

z

)

}

{\rm{Re}}\{{f}_{k}\left(z)\hspace{-0.08em}\text{/}\hspace{-0.08em}f\left(z)\}

,

Re

{

f

′

(

z

)

/

f

k

′

(

z

)

}

{\rm{Re}}\{{f}^{^{\prime} }\left(z)\hspace{-0.08em}\text{/}\hspace{-0.08em}{f}_{k}^{^{\prime} }\left(z)\}

and

Re

{

f

k

′

(

z

)

/

f

′

(

z

)

}

{\rm{Re}}\{{f}_{k}^{^{\prime} }\left(z)\hspace{-0.08em}\text{/}\hspace{-0.08em}{f}^{^{\prime} }\left(z)\}

, where

f

(

z

)

f\left(z)

belongs to the subclass

J

p
,
q

m

(

μ
,
α
,
β

)

{{\mathcal{J}}}_{p,q}^{m}\left(\mu ,\alpha ,\beta )

of analytic functions, defined by Sălăgean

(

p
,
q

)

\left(p,q)

-differential operator. In addition, the inclusion relations involving

N

δ

(

e

)

{N}_{\delta }\left(e)

of this generalized function class are considered.
The inhibitory effect of conditioned pain modulation on temporal summation in low-back pain patients
Authors: O’Neill Søren , Holm Liam , Filtenborg Johanne Brinch , Arendt-Nielsen Lars , Nim Casper Glissmann
Published: May 2021

Objectives

The literature on conditioned pain modulation (CPM) is inconclusive in relation to low-back pain and it is unclear how CPM affects temporal summation as a proxy of central pain integration. The aim of this study was to examine whether the CPM effect would be different on pain induced by temporal summation than single stimuli in a group of low back pain patients.

Methods

A total of 149 low-back pain patients were included. CPM was examined using single, repeated and temporal summation (repeated-single difference) of mechanical pressure pain as test stimuli at an individualized, fixed supra-pain-threshold force, before and after 2 min of cold pressor test (0–2 degrees Celsius). Participants were categorized as CPM responders or non-responders according to three different criteria: simple (any pain inhibition), strict (pain inhibition of more than 10VAS) and reversed (pain inhibition or facilitation of less than 10VAS). Clinical data on back pain was collected for correlation and descriptive purposes.

Results

Significant modulation was observed for all three test stimuli. Effects sizes were comparable in relative terms, but repeated pressure pain modulation was greater in absolute terms. No correlations to clinical data were observed, for any measure.

Conclusions

The current data suggests that repeated pressure pain may be better suited as the CPM test stimuli, than single pressure pain and temporal summation of pressure pain, as the CPM effect in absolute terms was greater. Employing temporal summation as the test stimulus in a CPM paradigm may be more sensitive than a single test stimulus.
Immunoregulation and antidepressant effect of ketamine
Authors: Zhang Nan , Yao Lihua , Wang Peilin , Liu Zhongchun
Published: May 2021

Major depressive disorder (MDD) is a common mental health disorder that brings severe disease burden worldwide. Traditional antidepressants are mainly targeted at monoamine neurotransmitters, with low remission rates and high recurrence rates. Ketamine is a noncompetitive glutamate N-methyl-d-aspartate receptor (NMDAR) antagonist, and its rapid and powerful antidepressant effects have come to light. Its antidepressant mechanism is still unclarified. Research found that ketamine had not only antagonistic effect on NMDAR but also strong immunomodulatory effect, both of which were closely related to the pathophysiology of MDD. Although there are many related studies, they are relatively heterogeneous. Therefore, this review mainly describes the immune mechanisms involved in MDD and how ketamine plays an antidepressant role by regulating peripheral and central immune system, including peripheral inflammatory cytokines, central microglia, and astrocytes. This review summarizes the related research, finds out the deficiencies of current research, and provides ideas for future research and the development of novel antidepressants.
Enhanced Synaptic Transmission in the Extended Amygdala and Altered Excitability in an Extended Amygdala to Brainstem Circuit in a Dravet Syndrome Mouse Model
Authors: Yan Wen Wei , Xia Maya , Chiang Jeremy , Levitt Alyssa , Hawkins Nicole , Kearney Jennifer , Swanson Geoffrey T. , Chetkovich Dane , Nobis William P.
Published: May 2021

Dravet syndrome (DS) is a developmental and epileptic encephalopathy with an increased incidence of sudden death. Evidence of interictal breathing deficits in DS suggests that alterations in subcortical projections to brainstem nuclei may exist, which might be driving comorbidities in DS. The aim of this study was to determine whether a subcortical structure, the bed nucleus of the stria terminalis (BNST) in the extended amygdala, is activated by seizures, exhibits changes in excitability, and expresses any alterations in neurons projecting to a brainstem nucleus associated with respiration, stress response, and homeostasis. Experiments were conducted using F1 mice generated by breeding 129.Scn1a+/−mice with wild-type C57BL/6J mice. Immunohistochemistry was performed to quantify neuronal c-fosactivation in DS mice after observed spontaneous seizures. Whole-cell patch-clamp and current-clamp electrophysiology recordings were conducted to evaluate changes in intrinsic and synaptic excitability in the BNST. Spontaneous seizures in DS mice significantly enhanced neuronal c-fosexpression in the BNST. Further, the BNST had altered AMPA/NMDA postsynaptic receptor composition and showed changes in spontaneous neurotransmission, with greater excitation and decreased inhibition. BNST to parabrachial nucleus (PBN) projection neurons exhibited intrinsic excitability in wild-type mice, while these projection neurons were hypoexcitable in DS mice. The findings suggest that there is altered excitability in neurons of the BNST, including BNST-to-PBN projection neurons, in DS mice. These alterations could potentially be driving comorbid aspects of DS outside of seizures, including respiratory dysfunction and sudden death.
“It Feels Right to Me”
Authors: Cvetkovich Ann
Published: May 2021

Focusing in particular on how affect theory has been informed by art practice, this article develops the concept of the “sovereignty of the senses” through queer and feminist installation projects by Rachael Shannon and Zoe Leonard, as well as Alison Bechdel’s account of retreat from the social in her graphic narrative memoir Are You My Mother? (2012). Aiming to articulate notions of sovereignty, democracy, and freedom in affective and sensory terms, it conceives of sovereignty as an embodied practice and something that must be learned and experienced collectively over time rather than a fixed condition of a discrete individual or nation. It explores tensions between Indigenous notions of sovereignty and queer notions of the antisocial or non-sovereign, as well as recent discussions of the commons as an affective category, to offer an anti-racist and decolonial account of queer feminist affect theory and cultural politics.
Recognition Method of Mine Water Sources Based on Factor Analysis
Authors: Li Yue  , Shi Longqing
Published: May 2021

Taking Jiaozuo mining area as the research background, according to the survey of water samples among the main water-filled aquifers of the mine and water gushing sources due to the exploitation of the No.21 coal seams in Shanxi group, six kinds of water chemical composition were selected as the sample indexes, including Cl-, SO42-, HCO3-, Na++K+, Ca2+, Mg2+, based on the data of groundwater chemical composition, and a principal component analysis was applied to establish the mathematical model by the method of factor analysis. A piper diagram was used to intuitively conduct the synthetical analyses for the general chemical characteristics and water quality types of the water samples. At the same time, via the comparative analysis between the water properties of water exits and that of the main aquifers in the Jiaozuo mining area, discrimination of the hybridization of the multiple water gushing sources due to coal mining was done. Moreover, by dint of the SPSS factor analysis, the water chemical proxies were carried on dimensionality reduction from the six kinds of water chemical composition to the three major factors, which replaced the original variables to participate in the data modeling. The results of the study showed that the combination of the piper diagram and the factor analysis modeling could effectively identify the water gushing sources owing to exploiting the No.21 coal seams of the Shanxi group in the Jiaozuo mining area and rank on the basis of the contributions of each aquifer to the amounts of water bursting in the mine, solving the problems of information superposition and correlations consisted in the identification of water gushing sources, which provides a theoretical basis for the prevention and cure of the mine water disasters.
Conhecendo o nosso passado a partir da história local
Authors: Bezerra de Azevedo Filho Jefson , Salles André Mendes
Published: May 2021

O artigo em tela tem como objetivo apresentar e refletir sobre um projeto – intitulado “Seridó: nas pegadas da História” – desenvolvido no Programa Residência Pedagógica (PRP), da Licenciatura em História da Universidade Federal do Rio Grande do Norte (UFRN), Campus Caicó. O referido projeto foi desenvolvido na Escola Estadual Antônio Aladim (EEAA), na Cidade de Caicó, RN. Durante o primeiro semestre de 2019, bolsistas residentes do PRP desenvolveram aulas e atividades que debatiam sobre os conceitos de memória, identidade, patrimônio e história local. A culminância do projeto foi uma aula de campo que teve como roteiro os principais pontos históricos da cidade de Caicó. Os resultados reforçam a importância de se trabalhar educação patrimonial e história local no currículo escolar, visto que possibilita ao aluno se perceber enquanto agente produtor da história.
Ultrahang-elasztográfia alkalmazásának lehetőségei a szülészet-nőgyógyászatban
Authors: Kozma Bence , Pákozdy Krisztina , Lampé Rudolf , Berényi Ervin , Takács Péter
Published: May 2021

Összefoglaló. Az ultrahang-elasztográfia az elmúlt évek során egyre
növekvő figyelmet kapott a lágyszövetek elaszticitásának vizsgálatában. A
módszer használatát az teszi szükségessé, hogy egyes, a mechanikai
tulajdonságaikban különböző szövetek hasonló echogenitásúak lehetnek, valamint
hogy egy adott szövet megváltozott struktúrája vagy mechanikai tulajdonsága nem
minden esetben jár együtt a szövet hagyományos ultrahangképének megváltozásával.
Az elmúlt évtizedben a deformációs és a nyírási ultrahang-elasztográfia vált
széles körben elérhetővé. Ezen új képalkotási technika egyre nagyobb szerepet
tölt be a szülészeti-nőgyógyászati ultrahang-diagnosztikában is. A
nőgyógyászatban szerephez juthat az endometriosis és az adenomyosis
kimutatásában, valamint a benignus és a malignus cervicalis és ovarialis
képletek elkülönítésében. A nőgyógyászathoz hasonlóan a szülészetben is jelentős
változást hozhat az ultrahang-elasztográfia: alkalmas lehet a szülésindukció
sikerességének, a koraszülés bekövetkezésének és a praeeclampsia kialakulásának
előrejelzésére. Orv Hetil. 2021; 162(18): 690–695.

Summary. Ultrasound elastography has received significant attention
for the assessment and measurement of soft tissue elastic properties in recent
years. The advantage of ultrasound elastography lies in the fact that two
different tissues can share similar echogenicities but may have other mechanical
properties or, on the contrary, mechanical abnormalities of a designated tissue
do not necessarily go hand in hand with an altered appearance on a conventional
ultrasound image. In the last decade, strain and shear-wave elasticity imaging
methods have become the most widely available among commercial ultrasound
equipments. The importance of this new method expands rapidly also in the field
of obstetrics and gynecology. Ultrasound elastography has a promising role in
the diagnosis of endometriosis and adenomyosis and helps to differentiate benign
and malignant cervical and ovarian lesions. The use in the prediction of the
outcome of labor induction and preterm birth, and in the evaluation of
preeclampsia are emerging. Orv Hetil. 2021; 162(18): 690–695.
Implicaciones identitarias en la divulgación del patrimonio cultural a través de Internet: un estudio desde la Teoría del Framing
Authors: Piñeiro-Naval Valeriano , Igartua Juan José , Rodríguez-de-Dios Isabel
Published: May 2021

Esta investigación, centrada en el patrimonio de los municipios, procura señalar aquellos elementos culturales que, de manera latente, son reflejo de la identidad colectiva de las localidades a través de la red. Por tanto, se plantea que un sitio web municipal es un dispositivo identitario, construido sobre la base de objetos patrimoniales y sucesos históricos, que categorizan a un grupo social y, al mismo tiempo, lo diferencian de los demás colectivos. El objetivo de este trabajo radica, entonces, en identificar los componentes del patrimonio que acaparan mayor cobertura informativa en los portales de los municipios de España, para luego señalar el enfoque que predomina en cuanto a su caracterización; un encuadre basado en la dialéctica entre lo local y lo global. Para ello, se implementó un análisis de contenido sobre una muestra de 500 sedes web de todo el país. A la vista de los resultados, se puede postular que la identidad patrimonial de España está marcada por un cariz religioso, ya que las manifestaciones que mayor presencia suelen tener son las construcciones eclesiásticas (en el plano de lo tangible), así como los eventos litúrgicos (a nivel intangible).
NDSHA - The New Paradigm for RSHA - An Updated Review
Authors: Bela J. , Panza G. F.
Published: May 2021

A New Paradigm (data driven and not like the currently model driven) is needed for Reliable Seismic Hazard Assessment RSHA. Neo-Deterministic Seismic Hazard Assessment (NDSHA) integrates earthquake geology, earthquake science, and particularly earthquake physics to finally achieve a New (and needed) Paradigm for Reliable Seismic Hazard Assessment RSHA.Although observations from many recent destructive earthquakes have all confirmed the validity of NDSHA’s approach and application to earthquake hazard forecasting-nonetheless damaging earthquakes still cannot yet be predicted with a precision requirement consistent with issuing a red alert and evacuation order to protect civil populations. However, intermediate-term (time scale) and middle-range (space scale) predictions of main shocks above a pre-assigned threshold may be properly used for the implementation of low-key preventive safety actions, as recommended by UNESCO in 1997. Furthermore, a proper integration of both seismological and geodetic information has been shown to also reliably contribute to a reduction of the geographic extent of alarms and it therefore defines a New Paradigm for TimeDependent Hazard Scenarios: Intermediate-Term (time scale) and Narrow-Range (space scale) Earthquake Prediction.
Relationship between seismicity and active faults in Thanh Hoa province detected by local seismic network
Authors: N. Duong T. , Phong Lai Hop , N. Pham D. , H. Chen C. , T. Dinh V.
Published: May 2021

Thanh Hoa province belongs to the southwest part of Northwest Vietnam, which is considered a tectonically active region. In the area of Thanh Hoa province, there are three deep-seated tectonic faults, namely Son La-Bim Son, Song Ma, and Sop Cop. As predicted by scientists, these faults are capable of producing credible earthquakes that might be the strongest in the territory of Vietnam. Besides the three main seismogenic sources, in the province, there are other smaller active faults such as Thuong Xuan-Ba Thuoc and Thuong Xuan-Vinh Loc but the relationship of these faults with seismic activity is still rather blurred. This may due to the sparseness of the Vietnamese National Seismic Network which can not record adequately small earthquakes in the area. This paper presents new results of additional monitoring from a local seismic network using 12 Guralp - 6TD broadband seismometers that have been deployed in Thanh Hoa province since November 2009. We found that the Thanh Hoa area is not seismically quiet. The average number of earthquakes recorded by the network has reached 80 - 90 events per year and some of them have magnitude from ML 3.0 to 4.0.By integration of the earthquake epicenters derived from the local network and distribution of active faults, we can detect several earthquakes locating near the three active faults, not only along the main faults but also along its subsidiary faults. We focused on the active faults of Thuong Xuan-Ba Thuoc and Thuong Xuan-Vinh Loc by using the recent results of the gravity, seismic, and magnetotelluric data analyses. Several recorded earthquakes distribute along the two small faults and some of them reach magnitude 3.0 or greater on the ML scale. In this study, the Thuong Xuan-Vinh Loc is recognized as a seismogenic source. To identify seismic hazard potential caused by earthquakes generated from the active faults, segmentation of the Thuong Xuan - Ba Thuoc fault had been done based on geological and geomorphological indications and seismic activity, and then the peak ground acceleration was determined for each fault segment. Besides, a large number of earthquake epicenters do not have a good correlation with a specific fault, especially in the area of Thanh Hoa coastal plain, which is covered by thick layers of Neogene - Quaternary sediment. This shows that there may be hidden active faults in the area which are needed to study further.
Obstetric nurse and the factors that influence care in the delivery process
Authors: Oliveira Patricia Santos de , Couto Telmara Menezes , Oliveira Graziele Matos , Pires Jaqueline Alves , Lima Keury Thaisana Rodrigues dos Santos , Almeida Laís Teixeira da Silva
Published: May 2021

ABSTRACT Objective: To identify the factors that influence the improvement of obstetric nurse care in the delivery process. Methods: Descriptive exploratory study with a qualitative approach conducted at a teaching maternity hospital located in the city of Salvador, Bahia, Brazil with 20 obstetric nurses from the Obstetric Center. Data was collected through semi-structured interviews between June and September 2017 and was then subjected to the Thematic-Categorical Content Analysis proposed by Franco. Results: Six categories emerged from the analysis, which presented factors that favor the improvement of obstetric care in the delivery process and factors unfavorable to this care. These factors address power and gender relations among health professionals; recognition of obstetric nurses; physical space and bed occupation; interaction between woman/ companion, among others. Final considerations: The factors indicated by obstetric nurses reveal the need for improvements in the working conditions by managers and changes of behavior and codes of conduct of health professionals.