bluuebunny/crossref_metadata_2025 huggingface dataset:
Network topology and movement cost, not updating mechanism, determine the evolution of cooperation in mobile structured populations
Authors: Pires Diogo L. , Erovenko Igor V. , Broom Mark
Published: August 2023

Evolutionary models are used to study the self-organisation of collective action, often incorporating population structure due to its ubiquitous presence and long-known impact on emerging phenomena. We investigate the evolution of multiplayer cooperation in mobile structured populations, where individuals move strategically on networks and interact with those they meet in groups of variable size. We find that the evolution of multiplayer cooperation primarily depends on the network topology and movement cost while using different stochastic update rules seldom influences evolutionary outcomes. Cooperation robustly co-evolves with movement on complete networks and structure has a partially detrimental effect on it. These findings contrast an established principle from evolutionary graph theory that cooperation can only emerge under some update rules and if the average degree is lower than the reward-to-cost ratio and the network far from complete. We find that group-dependent movement erases the locality of interactions, suppresses the impact of evolutionary structural viscosity on the fitness of individuals, and leads to assortative behaviour that is much more powerful than viscosity in promoting cooperation. We analyse the differences remaining between update rules through a comparison of evolutionary outcomes and fixation probabilities.
Impact of patterns of language use and socio-economic status on a constructed response Situational Judgment Test (SJT)
Authors: Pan Xuan , Huang Vivian , Laumbach Sonia , Copeland H. Liesel , Akinola Modupeola , Rosenbaum Daryl , MacIntosh Alexander
Published: August 2023

The study explored the impacts of patterns of language use (PLU) and socio-economic status (SES) on Casper, a constructed-response situational judgment test (SJT). 10,266 applicants from two U.S. medical schools were grouped into self-reported balanced bilinguals, unbalanced bilinguals, English monolinguals, and English as a Second Language (ESL) students. A multicomponent SES composite was used to assess the degree of socioeconomic disadvantage (DSD). Results from a hierarchical regression analysis showed that after accounting for demographic variables, both PLU and DED were significant factors on applicants’ Casper performance. Bilingualism was associated with better Casper performance compared to English monolinguals and ESL students. No significant effect of speaking English as a native language was found on applicants’ Casper performance. English monolinguals and ESL students performed equivalently on Casper. Finally, high DSD was associated with better Casper performance than low DSD, and the impact of DSD on Casper held the same across all four language groups. These findings provide evidence that socio-cultural factors, such as PLU and DSD have important impacts on SJT performance. Further research is needed to understand the role of differences in language construction across socio-cultural factors on constructed-response SJT performance.
Joan Crawford: The Essential Biography, Lawrence J. Quirk and William Schoell (2021)
Authors: Razmadze Mariami
Published: August 2023

Review of: Joan Crawford: The Essential Biography, Lawrence J. Quirk and William Schoell (2021)

Lexington, KY: University Press of Kentucky, 344 pp.,

ISBN: 9780813180496 (pbk), $24.95
Marcel the Shell with Shoes On: Life Through Googly Eyes
Authors: Gutierrez Allan
Published: August 2023

Review of: Marcel the Shell with Shoes On: Life Through Googly Eyes

Marcel the Shell with Shoes On (2021)

USA

Director Dean Fleischer Camp

Runtime 90 minutes
The Plague Dogs (1982)
Authors: Smith Yaakov “Jacob”
Published: August 2023

Review of: The Plague Dogs (1982)

UK & USA

Director Martin Rosen

Runtime 85 minutes theatrical/103

minutes extended

Blu-ray

USA, 2019

Distributed by Shout Factory

(region A/1)
Conditions for transplantation of primordial germ cells in the yellowtail tetra, Astyanax altiparanae
Authors: Coelho Geovanna Carla Zacheo , Carvalho Gabriella Braga , Monzani Paulo Sergio , Lopez Lucia Suarez , do Nascimento Nivaldo Ferreira , Senhorini José Augusto , Yasui George Shigueki
Published: August 2023

Biotechniques, including surrogate propagation derived from primordial germ cell (PGC) transplantation, are valuable tools for the reconstitution of endangered fish species. Although promising, there are no previous studies reporting such approaches using neotropical fish species. The aim of this study was to establish germline chimeras in neotropical fish by using the yellowtail tetra Astyanax altiparanae as a model species of the order Characiformes. Germline chimeras were obtained after transplantation of PGCs cultivated under different conditions: saline medium and supplemented with DMEM, amino acids, vitamins, glutamine, pyruvate, and fetal bovine serum, and subsequently transplanted into A. altiparanae triploids and triploid hybrids from the cross between A. altiparanae (♀) and A. fasciatus (♂). The results indicate ectopic migration in host embryos after transplantation of PGCs cultivated in saline medium. However, PGCs cultivated in supplemented medium migrated to the region of the gonadal ridge in 4.5% of triploid and 19.3% in triploid hybrid. In addition, the higher expression of dnd1, ddx4 and dazl genes was found in PGCs cultivated in supplemented culture medium. This indicates that the culture medium influences the maintenance and development of the cultivated cells. The expression levels of nanos and cxcr4b (related to the differentiation and migration of PGCs) were decreased in PGCs from the supplemented culture medium, supporting the results of ectopic migration. This is the first study to report the transplantation of PGCs to obtain germline chimera in neotropical species. The establishment of micromanipulation procedures in a model neotropical species will open new insights for the conservation of endangered species.
Addressing the Challenges of Bioconjugate Medicines
Authors:   Abzena, Babraham Research Campus, Cambridge, CB22 3AT, United Kingdom, Frigerio Mark , Kang Fuan ,   Abzena, Babraham Research Campus, Cambridge, CB22 3AT, United Kingdom
Published: August 2023

The continuing advancements in bioconjugate medicines from delivery of potent cytotoxins to vaccine-, oligonucleotide-, radionuclide-, immunomodulator- and check-point inhibitor-conjugates, can start to address the large unmet medical need currently unattainable from current therapeutic approaches. As the field of bioconjugation develops, and the recent spate of antibody-drug conjugates (ADCs) approvals continues, the resulting knock-on effects for delivering a wider range of bioconjugated molecules will also continue to expand in utility.
AJICAP Second-generation: Realizing Versatility and Robustness through Fc-Affinity Guided Chemical Conjugation Technology
Authors:   Ajinomoto Co., Inc., 1-1, Suzuki-Cho, Kawasaki-Ku, Kawasaki-Shi, Kanagawa 210-8681, Japan., Fujii Tomohiro , Matsuda Yutaka ,   Ajinomoto Bio-Pharma Services, 11040 Roselle Street, San Diego, CA 92121, United States
Published: August 2023

Over the past decade, site-specific chemical conjugation has emerged as a promising strategy to produce antibody-drug conjugates (ADCs) in the field of oncology [1]. Daiichi-Sankyo’s chemical conjugation method, which uses high drug-to-antibody ratio (DAR) technology, was approved by the U.S. Food and Drug Administration as the first site-specific ADC (fam-trastuzumab-deruxtecan-nxki; Enhertu® | Daiichi Sankyo and AstraZeneca). However, owing to limitations in high-DAR technology and the potential need for DAR=2 production, the Ajinomoto group has been developing a chemical site-specific conjugation technology using Fc-affinity peptide reagents since 2019 [2]. This approach modifies a specific lysine in the Fc region of various antibodies such as IgG1, IgG2, and IgG4 to create homogeneous DAR=2 ADCs, as demonstrated in a proof-of-concept study.
A tudatos jelenlét öt aspektusának mérésére alkalmas kérdőív (FFMQ-24) hazai adaptációja és 10. évfolyamos tanulók körében végzett előméréseinek eredményei
Authors: Budis Imola
Published: August 2023

A mindfulness egy meglehetősen új kutatási terület Magyarországon, a neveléstudomány területén egyáltalán nincs erre a jelenségre irányuló empirikus vizsgálat. Tanulmányunk célja, hogy beszámoljon a tudatos jelenlét mérésére alkalmas Five Facet Mindfulness Questionnaire (FFMQ-24) mérőeszköz hazai adaptálási folyamatáról és két, 10. évfolyamosok körében kivitelezett előmérésének eredményeiről. Az SPSS, Jamovi és Smart- PLS3 programok segítségével elvégzett, részletes statisztikai adatelemzés által vizsgáltuk az adaptált kérdőív működését és jóságmutatóit. Mindezt annak érdekében, hogy megfelelő megbízhatósággal, faktorszerkezettel és itemszintű diszkriminációs validitás-értékekkel bíró kérdőívváltozatot hozzunk létre. Az első mérés eredményei mentén átdolgozott kérdőívváltozatot alkalmaztuk a második mérésben. Az utóbbi eszközváltozat faktorstruktúrája és belső konzisztenciája a kis mintaelemszám (n = 66) ellenére is kifejezetten jó. Az RMSEA-érték (0,080) szintén kiváló illeszkedést jelez. Három item nem illeszkedett tökéletesen. A tudatos cselekvés alskála részét alkotó 23. tétel valószínűleg az individuális preferenciák miatt nem működött megfelelően. A reagálásmentesség faktorhoz tartozó 18. és 21. állítások esetében pedig a vírushelyzet látens hatásai befolyásolhatták a részt vevő diákok válaszadási mintázatait. A teljes kérdőív jó megbízhatósággal rendelkezik (α = 0,803). Az öt alskála közül egyedül a tudatos cselekvés Cronbach-α (= 0,487) értéke kevésbé jó, ugyanakkor a szerkezeti megbízhatóságot mutató CR értéke (0,711) elfogadható, tehát az itemek betöltik funkciójukat, adatgyűjtésre alkalmasak. A többi alskála reliabilitás- (α = 0,586-0,779) és CR-értékei (0,696–0,850) megfelelő működésre utalnak. Összegezve az eredményeket, a második kérdőívváltozat hazai adatgyűjtésre használható, megbízható és a tudatos jelenlét mérésére alkalmas mérőeszköznek ítélhető.
Deserción universitaria: investigación con jóvenes evadidos del curso de Administración de una IES confesional
Authors: Santos Marcos Aurélio Corrêa dos , Vieira Almir Martins , Coelho Patrícia Margarida Farias
Published: August 2023

El fenómeno de la deserción en la enseñanza superior viene siendo investigado en diferentes escenarios, abordajes metodológicos y cortes temporales. El alcance de esta investigación se encuentra en entender por qué el joven estudiante de una institución de enseñanza superior (IES) confesional perde su interés en cursar administración. A través de una investigación cualitativa, por el método del estudio de caso, esta investigación objetivó levantar los motivos que llevan a los jóvenes de una institución de enseñanza superior confesional a abandonar el curso de Administración antes de su final. Los resultados han evidenciado que la deserción del joven investigado puede originarse de una acumulación de factores que generan insatisfacción y frustración con la experiencia estudiantil, como cuestiones pedagógicas, administrativas y personales. Además, es necesario señalar que los profesores necesitan comprender la necesidad de resignificar el aprendizaje para estos nuevos discentes. Dado este panorama, parece ser razonable asumir que este trabajo puede ayudar a comprender el universo juvenil y sus insatisfacciones, sobre todo en el plano de la enseñanza superior. Aparte de estos aspectos, estudios futuros en otros cursos, otras instituciones y también en otras regiones del país, podrán auxiliar en la construcción de un panorama más completo sobre el tema.
Fairy-Tale Design and the Heroine’s Transition to the Ordinary World
Authors: Arif Saffeen N.
Published: August 2023

Like many of her contemporaries, the fictional works of the Canadian writer Alice Munro can be read as a realistic portrayal of the people from her native Ontario, Canada, describing their set of beliefs, values, dreams, aspirations, fears, and apprehensions. A second way to evaluate this fiction is to approach it from a feminist perspective, shedding light on the question of women’s need to be free from the patriarchal rule. The aim of this article, however, is to consider the function of the fairy-tale framework by which Munro’s short story “Red Dress – 1946” is constructed. This fairy-tale design is considered a point of departure from which the story’s heroine grows mentally and spiritually so that she can get her way into the normal world. In addition to taking a brief look at some of the views offered by Munro’s critics of her writings, it also tries to answer such questions as, what function(s) does this form perform to the story to bring about the heroine’s development? Aside from where the Bildungsroman and fairy tale genres meet and where they deviate, how far are certain traditional fairy-tale elements, such as structure, themes, characterization, etc. significant in bringing about the heroine’s mental as well as emotional growth?
Documentary data collection: an initial step for information management in the conservation and restoration of cultural heritage
Authors: Korro Jaione , Valle-Melón José Manuel , Rodríguez Miranda Álvaro
Published: August 2023

Architectural heritage documentation is a preliminary step to address any heritage conservation and management problem. However, data collection is often isolated resulting in lack of communication between different data types and incomplete documentation. This text examines the wide-ranging collection of technical and administrative documentation concerning to the successive conservation-restoration works carried out in the monastery of San Millán de la Cogolla de Yuso (La Rioja, Spain) since its declaration as a UNESCO World Heritage site in 1997. The main objective is to propose a document management system which can support an efficient long-lasting safeguard and also allows new uses and additional values. This aim entails the consideration of information retrieval (when the documents are scattered across many archives), classification (a normalised and comprehensive classification chart is lacking for the documents generated in conservation-restoration), and description (a list of metadata needs to be benefit of future users and any other additional uses).
Things rust but memories last forever: creative conservation in the industrial heritage
Authors: Triães Ricardo , Chasqueira Ânia , Ferraz Ângela
Published: August 2023

The concept of creative conservation began to be developed in 2012 by conservators from the Polytechnic Institute of Tomar. This approach, which begins with a process of resignification of fragmented objects, those apparently without possible recovery and on the verge of being discarded, has the goal to develop actions that encourage reflective thinking on preservation and collective memory. This article explores its application in industrial heritage through two case studies: Cartão de Ponto project (2012), based on the conservation of a set of timecards of former workers of the Spinning Mill of Tomar, and the ongoing POR1FIO project, which seeks to create an educational tool from preserved objects from the Torres Novas Nacional Spinning & Weaving Co. These projects demonstrate that creative conservation approach can be a new strategy to help the local community to establish positive memories based on their industrial heritage and to manage the trauma from the de-industrialization processes.
Grenzverhandlungen: Zu Narrativen des Posthumanen in Katja Brandis und Hans-Peter Ziemeks "Ruf der Tiefe"
Authors: Njanjo Burrhus , Tezokeng Klaus
Published: August 2023

Der vorliegende Beitrag erschließt Narrative des Posthumanen in Katja Brandis und Hans-Peter Ziemeks Roman Ruf der Tiefe (2011). Dabei wird das Augenmerk auf literarische Darstellungsweisen von Hybridisierungsprozessen und Verwobenheiten zwischen Natur und Kultur gerichtet. Die Studie stützt sich auf Posthumanismus-Ansätze nach der neu-Deleuzianischen Theoretikerin Rosi Braidotti und fragt besonders danach, wie anthropozentrische hierarchische Dynamiken literarisch überwunden werden und neue nomadische Subjektkonstitutionen ästhetisch perspektiviert werden. Ferner wird die Rekonfiguration der Beziehung zu einem gemeinsamen Lebensraum in Brandis und Ziemeks Roman untersucht.
The Public History Turn in History Education Seen Through the Lens of the Polish–German History Textbook
Authors: Wojdon Joanna
Published: August 2023

This article presents the changes in history education that bring school history closer to public history and discusses the potential of a textbook as a tool for fostering public history. The analysis of the chapters dealing with the Second World War from the Polish–German history textbook, Europe – Our History, provides arguments in support of the claim that history education may become history for the public – by engaging pupils, not just providing them with knowledge; with the public – by letting the pupils reflect on the lesson content, not take it for granted; about the public – by focusing on ordinary people’s fates, not on political and military operations; and by the public – by referring extensively to people’s memories and letting primary sources speak for themselves, not just illustrate the historiographical narrative.
A preliminary examination of burrow use of the understudied Ctenomys pilarensis in Ñeembucú, Paraguay
Authors: Hordijk Kim Anna Cornelia , Pottie Sam Bert , Ayala Jorge
Published: August 2023

Very little is known on Ctenomys pilarensis, as it has rarely been studied. We conducted a preliminary study on its burrow use by implementing a capture-mark-recapture method. Between February and June 2022, 12 different Pilar tuco-tucos were captured and chipped using MiniHPT8 PIT tags, 7 individuals were recaptured at least once. Our results indicate this species to be solitary, as we found no evidence of burrow sharing. These findings should, however, be viewed with caution due to our small sample size.
Para-occupational exposure to chemical substances: a systematic review
Authors: Ramezanifar Soleiman , Azimian Afsane , khadiv Elahe , Naziri Seyed Husein , Gharari Noradin , Fazlzadeh Mehdi
Published: August 2023

Today, many health problems related to work have overshadowed workers and their families. In the meantime, chemicals are among the risk factors that have created many problems due to para-occupational exposure. In para-occupational exposures, family members are exposed to work pollutants transferred to the home environment. This study was conducted to investigate para-occupational exposure to chemicals. To conduct this systematic review, databases such as “Web of Science”, “Google Scholar”, “Scopus”, and “SID” were used. Relevant articles in these databases were extracted by searching keywords such as “take-home exposure”, “para-occupational exposure”, and “chemicals” from 2000 to 2022. To extract the required data, all parts of the articles were reviewed following the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA 2020). Among the 44 identified articles, 23 were selected as final articles, of which 10 were related to agriculture workers and their families, and 13 were related to other occupations. These studies mainly investigated para-occupational exposure to pesticides (14 studies) and metals (four studies). Also, contaminated work clothes, the washing place of contaminated clothes, and storage of working clothes, equipment, and chemicals were proposed as the main routes of contamination transmission. As a result of these para-occupational exposures, problems like neuro-behavioral disorders in children, end-stage renal disease, black gingival borders, and autism spectrum disorder were created or aggravated. Limiting the transmission routes and taking measures such as training and providing facilities like devoting places for washing and storing clothes in the workplaces can decrease this type of exposure.
Pathogenesis underlying hexanucleotide repeat expansions in C9orf72 gene in amyotrophic lateral sclerosis
Authors: Chong Zhao Zhong , Menkes Daniel L. , Souayah Nizar
Published: August 2023

Amyotrophic lateral sclerosis (ALS) is a rapidly progressive and fatal neurodegenerative disorder. Mutations in C9orf72 and the resulting hexanucleotide repeat (GGGGCC) expansion (HRE) has been identified as a major cause of familial ALS, accounting for about 40 % of familial and 6 % of sporadic cases of ALS in Western patients. The pathological outcomes of HRE expansion in ALS have been recognized as the results of two mechanisms that include both the toxic gain-of-function and loss-of-function of C9ORF72. The gain of toxicity results from RNA and dipeptide repeats (DPRs). The HRE can be bidirectionally transcribed into RNA foci, which can bind to and disrupt RNA splicing, transport, and translation. The DPRs that include poly-glycine-alanine, poly-glycine-proline, poly-glycine- arginine, poly-proline-alanine, and poly-proline-arginine can induce toxicity by direct binding and sequestrating other proteins to interfere rRNA synthesis, ribosome biogenesis, translation, and nucleocytoplasmic transport. The C9ORF72 functions through binding to its partners-Smith-Magenis chromosome regions 8 (SMCR8) and WD repeat-containing protein (WDR41). Loss of C9ORF72 function results in impairment of autophagy, deregulation of autoimmunity, increased stress, and disruption of nucleocytoplasmic transport. Further insight into the mechanism in C9ORF72 HRE pathogenesis will facilitate identifying novel and effective therapeutic targets for ALS.
„do you really beLIEVE that.“ – Positionierungen von Lehrkräften zu Verschwörungstheorien im Spannungsfeld von Epistemik, Vertextungsform und Institution
Authors: Weiser-Zurmühlen Kristin , Schildhauer Peter , Gerlach David
Published: August 2023

We analyse how teachers position themselves towards conspiracy theories in teaching contexts following the methodology of conversation analysis and positioning theory. For the analysis we selected sequences in which three teachers narrate and comment retrospectively on incidents from their everyday school life in which their students confronted them with conspiracy theories. Since conspiracy theories are seen as a complex and potentially explosive phenomenon in both public and academic discourse, many see it as mandatory to take or at least express a critical stance towards them. In general, however, conspiracy theories make it difficult to take a clear position, as they are often vague and incoherent on evaluative, textual, functional and epistemic levels. These ambiguities are also reflected in the teachers’ positions as evidenced in our data: On the one hand, they emphasise the need to raising students’ awareness of how to identify conspiracy theories and how to adopt a critical stance towards them. On the other hand, the micro-analytical reconstruction of the narrative sequences of concrete classroom situations shows that the teachers do not always act in line with these beliefs. This can be interpreted as a tension between socially conforming positioning acts towards conspiracy theories on the one and the teachers‘ professional self-perception on the other hand.
Self-Verifying Depression in Retrospect: More Depressed People Reconstruct the Past to Seem More Depressed
Authors: Hart William , Cease Charlotte K. , Lambert Joshua T. , Witt Danielle E.
Published: August 2023

Introduction: Self-verification theory makes the controversial claim that people higher in depression seek to confirm their depressed identity. Recent evidence suggests that people with higher self-reported depression severity alter their reports of self-relevant information to seem depressed. This article discusses the results of two preregistered studies that examined whether people with higher self-reported depression severity will distort memories of previously encoded events to seem depressed. Methods: In Studies 1 and 2, participants (total N = 665) self-reported their depression severity and then completed a (sham) perceptual task that could presumably diagnose the possession of a brain type that causes depression symptoms. Results: Across the two studies, depression severity (apart from negative affectivity or gender) was related to how people distorted their memories on the task; specifically, people with relatively “high” depression severity distorted their recalls to seem as if they had the depression-prone brain, and people with relatively “low” depression severity showed the opposite bias. These effects did not involve conscious awareness of distortion and had downstream effects on people's self-concepts. Discussion: Broadly, the data align with the possibility that people relatively higher in depression are prone to exhibit biases in reconstructive memory that validate their depressive symptoms.
Supporting Physicians During the COVID-19 Pandemic: A Cumulative Feminist Autoethnography
Authors: Hernandez Barbara Couden , ChenFeng Jessica L. , Schwenke Naomi J.
Published: August 2023

Three marriage and family therapists discuss their experience providing therapy and support interventions for physicians during the COVID-19 pandemic. They present three feminist autoethnographic accounts about the unique intersectionality of their lives as they served physicians on the frontlines of the pandemic whilst also negotiating the pandemic themselves. Three themes from the narratives are presented and explored and implications are given for other therapists whose clinical services for medical care professionals also carried a personal and emotional cost.
Madison Grant and the Dark Side of the Conservation Movement
Authors: Wheeler Jim
Published: August 2023

James B. Wheeler, a career Park Ranger/Interpreter with the National Park Service and interpreter in North Coast Redwoods State Parks, wrote a letter before retiring in 2017 to his superiors and other Parks employees about Madison Grant’s history, positive and negative. He asked for an adjustment to the stories told by the Prairie Creek memorial to Grant and the Founders Tree monument. His plea went unheard at the time, but it is central to the victory for historical truth and human decency that was achieved in more recent years. It is included here in its entirety as a necessary historical document (lightly edited for clarity and grammatical consistency).
Tree-Mining: Understanding Applications and Challenges
Authors: Pathak Anubha , Saxena Sameer
Published: August 2023

Tree-mining is an essential system of techniques and software technologies for multi-level and multi-angled operations in databases. Pertaining to the purview of this manuscript, several applications of various sub-techniques of tree mining have been explored. The current write-up is aimed at investigating the major applications and challenges of different types and techniques of tree mining, as there have been patchy and scanty investigations so far in this context. To accomplish these tasks, the author has reviewed some of the latest and most pertinent research articles of the last two decades to investigate the titled aspects of this technique.
Design of chemically recyclable nanocellulose chiral liquid crystal photonic elastomer vitrimer and its mechanosensitive colour-changing materials
Authors: Zhang Jinlong , Li Weiguo , Wu Qinglin
Published: August 2023

The development of nanocellulose (CNCs) chiral liquid crystal photonic elastomeric vitrimer materials is promising for achieving needed reduction in carbon emissions (elastomer material recycling) and developing novel photonic functional materials. The primary questions discussed are about what is the basic principle of chiral liquid crystal and photonic property of CNCs, how to design vitrimer elastomer materials, and what is the general approach to designing CNC chiral liquid crystal photonic elastomer vitrimer and mechanosensitive colour-changing materials.
Política tributaria y formalización de las micro y pequeñas empresas en Lima Metropolitana
Authors: Ramirez Campomanes Clesy Rosilene
Published: August 2023

Objetivo: Determinar la relación entre la política tributaria y la formalización de las micro y pequeñas empresas en Lima Metropolitana. Método: Se utilizó el enfoque cuantitativo; el diseño fue no experimental, transversal, de tipo relacional porque permitió asociar las variables, para ello, se utilizó la prueba chi-cuadrado de Pearson. La muestra fue de 384 mypes. Resultados: De las 384 mypes, un 23,44 % (90) respondió que ningún tributo es difícil de pagar y, a pesar de que un 10,42 % (40) contestó que los impuestos que se pagan a la Superintendencia Nacional de Aduanas y de Administración Tributaria fueron los tributos más difíciles de pagar, al igual que los tributos municipales con un 27,08 % (104), se halló que el 64,85 % (249) está acogido a un régimen tributario, donde el mayor porcentaje pertenece al nuevo RUS con el 50,3 % (193). Conclusión: La política tributaria tiene una relación significativa con la formalización de las micro y pequeñas empresas en Lima Metropolitana.
Nutritional Strategies to Optimize Outcomes among Infants with Congenital Heart Disease
Authors: Miller Audrey N. , Naples Angelo
Published: August 2023

Growth failure is common among infants with congenital heart disease (CHD), affecting approximately half of all infants with CHD. Achieving good growth is difficult secondary to both cardiac and noncardiac factors that affect energy expenditure and nutritional intake. Growth failure is associated with poor outcomes, including mortality, prolonged length of hospital stay, delayed cardiac surgery, postoperative complications, and neurodevelopmental delay. Clinical practice varies widely when it comes to how nutrition is managed in these infants, with varying approaches to enteral feeding initiation, advancement, and discontinuation. This variation persists despite several practice guidelines that have been created in recent years to guide nutritional care. Standardized feeding protocols have been proven to reduce growth failure and improve outcomes for this patient population. Centers and clinicians should be encouraged to adopt existing guidelines, or create their own from evidence-based literature, to improve growth and outcomes for infants with CHD.
Multicenter Clinical Research in Congenital Heart Disease: Leveraging Research Networks to Investigate Important Unanswered Questions
Authors: Schwartz Bryanna N. , Pearson Gail D. , Burns Kristin M.
Published: August 2023

Congenital heart disease (CHD) is the most common birth defect in the United States. Neonates with CHD are often cared for by neonatologists in addition to cardiologists. However, there is a paucity of rigorous evidence and limited clinical trials regarding the management of neonates with CHD. In this review, we will describe some of the challenges of research in this field. The Pediatric Heart Network serves as an example of how a research network can effectively overcome barriers to conduct and execute well-designed multicenter studies.
What Came First: Malnutrition or Severe Disease?
Authors: Carey Megan N. , Cameron Lindsay H. , Rider Nicholas L. , Hergenroeder Albert , Cohen Adam
Published: August 2023

A 20-year-old female with depression presented to the emergency department with chronic weight loss, weakness, fatigue, hair loss, rash, palpitations, and 2 weeks of cough. Initial history revealed that she had disordered eating habits with dietary restriction, experienced a 50-pound unintentional weight loss over 2 years despite reported adherence to nutritional supplementation, and had a normal gastrointestinal workup. On examination, she was markedly cachectic with a BMI of 10.3kg/m2 and hypotensive (84/69 mmHg). Her cardiovascular examination revealed a regular rate and rhythm without a murmur. Her breath sounds were diminished in the upper lobes bilaterally. A skin examination showed diffuse hair loss, skin breakdown, and peeling with a tender, erythematous, papular rash over the bilateral ankles, and nonpitting edema. A chest radiograph showed a right upper lobe opacity and lucent lesions in the left proximal humerus. A focused assessment with sonography for trauma examination showed a large pericardial effusion. Chest computed tomography revealed a right upper lobe opacity with an associated cavitation. Though she began improving with rifampin, isoniazid, pyrazinamide, ethambutol, levofloxacin, azithromycin, and nutritional rehabilitation, her clinical course was complicated by an acute worsening nearly 1 month into her hospitalization with persistent high fevers, worsening cough, development of a murmur, and worsening consolidation on chest computed tomography. Adolescent Medicine, Infectious Diseases, Gastroenterology, and Allergy and Immunology were consulted to guide the diagnostic evaluation and management of this patient’s complex clinical course.
Subjetividad afectiva e infancia queer: Un análisis de la película Wild Tigers I Have Known
Authors: Brenes Vargas Alonso
Published: August 2023

Este ensayo propone un análisis crítico sobre la subjetividad afectiva de una infancia queer, a partir de la película de Cam Archer Wild Tigers I Have Known. Se pretende así aportar una comprensión sobre cómo la violencia heteronormativa se imprime en la afectividad de le «niñe queer».
realismo materialista abierto de Xavier Zubiri y la filosofía de la realidad histórica de Ignacio Ellacuría
Authors: Samour Héctor
Published: August 2023

El artículo analiza los principales argumentos del pensamiento filosófico zubiriano desde la interpretación de Ignacio Ellacuría con el fin esclarecer la forma en que sus tesis metafísicas, antropológicas y epistemológicas se asumen en la construcción de la concepción de la realidad histórica y en la idea de la función política y liberadora de la filosofía.
Derechos humanos desde la Filosofía de la realidad histórica
Authors: Rosillo Martínez Alejandro
Published: August 2023

En este artículo, se desarrolla una comprensión de los derechos humanos desde un paradigma complejo, con base en la Filosofía de la realidad histórica de Ignacio Ellacuría. Para tal objetivo, se sigue el esquema propuesto en su texto “Hacia una conceptualización de los derechos humanos”, que consiste en diez afirmaciones. Cada uno de estos conceptos es profundizado, en conexión con otros textos de Ellacuría, para dar cuenta de lamanera en que se repiensan los derechos humanos desde la Filosofía de la realidad histórica.
Antinomias filosóficas en la pintura: Vermeer y Friedrich
Authors: Noel Lapoujade María
Published: August 2023

A partir del epígrafe de Leonardo la premisa fundamental de este artículo es que así como la pintura es filosofía, también la filosofía es pintura. Sostengo que así como la pintura expresa en imágenes visuales diversos problemas filosóficos, también la filosofía puede aplicarse, “aterrizarse” concretamente en la pintura. Con base en la premisa el propósito de este artículo es el de mostrar que las pinturas de Jan Vermeer y de Caspar Friedrich son un campo fértil para formular ciertas antinomias conceptuales, abstractas, a partir de las imágenes visuales pictóricas. Por su parte, la literatura ha expresado en poesías y prosas poéticas memorables, el esplendor de la pintura respecto de nuestro tema, además, desbordándolo. Me refiero en particular a Wolfang Goethe, Rainer-María-Rilke, Marcel Proust, Giusseppe Ungaretti. De modo que el enfoque es interdisciplinario. La integración de pintura, música, literatura y filosofía logran poner de relieve una mayor densidad, espesor, encontrar la universalidad concreta de las obras en un tejido vivo.
Presentación biográfica-filosófica de Ernst Kapp
Authors: Coto Murillo Sebastián A.
Published: August 2023

El presente artículo se interesa enla filosofía de la técnica mediante la presentaciónde uno de sus pioneros, tal como fue ErnstKapp (1808-1896). En el artículo se detallan losaspectos biográficos más importantes de Kapp,así como un perfil de su pensamiento filosóficoa partir tanto de su obra más relevante como desu concepto de proyección.
¿Hay filosofía en los Vedas?
Authors: Antón Pacheco José Antonio
Published: August 2023

Habitualmente, en el mundo académico que se ocupaba del pensamiento de la India, era normal que se afirmara que en los cuatro Vedas no se encontraba nada de filosofía. Había que esperar al surgimiento de las Upaniṣad para que estuviéramos ante el fenómeno filosófico, fenómeno que luego desarrollarían las seis dársanas o sistemas clásicos del hinduismo (el budismo tiene su propia trayectoria). Solo René Guénon y sus seguidores atribuían a los Vedas la presencia de verdadera filosofía; metafísica, en palabras de Guénon.
períodos de formación del pensamiento indio: notas no esencialistas
Authors: Wulff Alonso Fernando
Published: August 2023

Se analizan los orígenes y consecuencias de cuatro aspectos esencialistas en la imagen del mundo “Védico-hinduista” en la antigüedad india: 1. Evolución orgánica y sin rupturas. 2. Hegemonía. 3. Una evolución sin contacto ni participación en componentes comunes con otras corrientes religiosas. 4. Aislamientorespecto al exterior del Subcontinente.
Diálogos del Amor y la Muerte: La victoria del amor en la filosofía india
Authors: Junco Ethel
Published: August 2023

La pandemia y sus primeras consecuencias visibles ponen al hombre ante un tipo de encrucijada que no puede ignorar y que exige opciones de reorientación. El arcano mundo de los relatos originarios de la Indiapone a disposición su capacidad simbólica para resignificarse en el decurso histórico; a tal efecto, proponemos recurrir al saber virtuoso de la tradición oriental para corroborar su tránsito y su renovación en sede de autor o en boca del pueblo anónimo. Consideraremos aquí una lectura en relación del relato de la reina Savitrî del Mahâbhârata y su transformación en dos tiempos: en visión griega, Alcestis de Eurípides y en visión maravillosa, La Bella Durmiente del bosque, según texto de Perrault y de los hermanos Grimm, todo através del tamiz de la figura de Orfeo.
Leo Löwenthal y Herbert Marcuse: la amistad como utopía redentora
Authors: Jansen Peter-Erwin , Engel Inka , García Quesada George
Published: August 2023

El 28 de octubre de 2021, desde el Miniauditorio de la Facultad de Letras de la Universidad de Costa Rica, el profesor Jansen dictó una conferencia basado en una versión en inglés de este texto (de su autoría y de la profesora Engel). Durante la transmisión por redes sociales, mientras el conferencista leía, se proyectaba en la pantalla el texto traducido al español, el cual con ligeras variaciones presentamos aquí al público lector.
Usos e interpretaciones profético-materialistas de El capital
Authors: Martínez Andrade Luis
Published: August 2023

La relación entre el marxismo y la Teología de la liberación ha sido explorada por algunos investigadores para señalar la existencia de afinidades electivas entre estas corrientes de pensamiento en la crítica del capitalismo. Este artículo aborda la lectura de El Capital que algunos teólogos de la liberación han realizado y, al mismo tiempo, muestra la manera cómo estos teólogos la incorporaron en su proyecto teórico.
En la hora de la barbarie: múltiples marxismos e identidad de izquierda en Bolívar Echeverría
Authors: González Jiménez Fernando Alejandro
Published: August 2023

En este trabajo se esboza una interpretación del texto En la hora de la barbarie de 1983 de Bolívar Echeverría, que constituye la primera versión de lo que posteriormente será la Presentación al libro de 1985 titulado El discurso crítico de Marx. En esta versión primitiva del texto nuestro autor ofrece su balance sobre el siglo XX a unas décadas de que éste finalizara y pone las bases para reconstruir lo que entenderá por “marxismos múltiples” su idea de la substancia-Marx, así como una consideración crítica sobre la identidad de la izquierda comunista.
Sigmund Freud y un embrollo siempre implícito en su explicación acerca de Dios
Authors: Mora Calvo Hernán
Published: August 2023

Establecer el sentido y dimensiones del tema de Dios en el pensamiento de Sigmund Freud es difícil y no se debe confundir con sus criterios sobre la religión. ¿En qué consiste el pensamiento freudiano sobre Dios y cómo se articula? ¿Se trata de un círculo vicioso o de un conflicto que progresa de definición en definición?
Estética neotomista en la orden de predicadores
Authors: Granados Valdéz Juan
Published: August 2023

Las estéticas del siglo XX han sido muchas y entre ellas hay una estética neotomista. El propósito de este trabajo es rastrear las ideas estéticas de algunos filósofos tomistas dominicos, probablemente los más conocidos del viejo mundo: Ceferino González y Díaz Tuñón O.P. (1831-1894); Heinrich Seuse Denifle O.P. (1844-1905); Norberto del Prado O.P. (1852-1918); Pedro Mandonnet O.P. (1858-1936); Ambrosio Gardeil O.P. (1859-1931); Antonin-Dalmace Sertillanges O.P. (1863- 1948); Gallus Manser O.P. (1866-1950); Édouard [Florentin-Louis] Hugon O.P. (1867-1929); Francisco Marín-Sola O.P. (1873-1932); Reginald Garrigou-Lagrange O.P. (1877-1964); Manuel Barbado O.P. (1884-1945); Santiago María Ramírez Ruíz de Dulanto O.P. (1891-1967); Abelardo Lobato O.P. (1925-2012); Sixto Castro (1970). Todos ellos han tenido amplio reconocimiento. No en todos los casos se ha conseguido hacer hallazgos en orden a la belleza y el arte.
Minima Moralia. La fractal crítica del valor de Th. W. Adorno
Authors: Montero Osvaldo
Published: August 2023

Este artículo realiza un trabajo exploratorio sobre algunos aspectos filosóficos presentes en la obra Minima Moralia de Th. W. Adorno. Se pretende rescatar los principales elementos relacionados a su crítica del valor como realidad totalizadora, dando cuenta de las consecuencias concretas manifestadas en la vida social y de las posibilidades asequibles para superar tal estado. Se parte de la hipótesis de que Minima Moralia constituye un elemento central de la crítica del valor en la versión de Adorno. En primer lugar, se presenta el contexto de publicación del escrito adorniano. A continuación, se investiga el papel de la experiencia en el pensamiento crítico del pensador. Después se precisa la importancia de la teoría de la apariencia e inversión real en la comprensión de este universo social, para cerrar el escrito con un análisis de las posibilidades objetivas de trascender lo dado y el papel de la felicidad en la Teoría crítica.
ser humano como ser supremo y la dialéctica antropológica del método de Marx
Authors: Bautista S. Juan José
Published: August 2023

El pensamiento crítico contemporáneo ya no está pensando desde los mismos presupuestos en los que se construyó el pensamiento crítico marxista y de izquierda del siglo XX. Apunta, sobre todo, a la propuesta de salidas al impasse político de la izquierda. El pensamiento que Franz Hinkelammert ha estado desarrollando en estos últimos años es un gran ejemplo de lo que podríamos hacer en aras de la construcción de este nuevo pensamiento. Es sobre esta línea que en el presente ensayo se desarrollan tres hipótesis que se sostienen como producto del diálogo con Hinkelammert, Marx, con E. Bloch y W. Benjamin La primera tiene que ver con los presupuestos implícitos en la antropología con la cual surge la modernidad. La segunda tiene que ver con la secularización moderna de los mitos presupuestos en las antropologías en la modernidad. Y la tercera hipótesis intenta situar el lugar que este tipo de reflexión antropológica tiene al interior de la dialéctica, tanto de Hegel, de Marx, como de la posible idea de dialéctica que se podría desarrollar a partir de este último.
“Estudiantes como sombras del futuro”: las voces de las víctimas de la masacre del 30 de julio de 1975 en las memorias públicas de la Universidad de El Salvador
Authors: Zúñiga Núñez Mario
Published: August 2023

Este articulo analizará las memorias públicas de las víctimas de la masacre de estudiantes del 30 de julio de 1975, perpetrada por las Fuerzas Armadas de El Salvador para reprimir una marcha por la autonomía universitaria. Se enfatizará en los puntos comunes en los testimonios que aparecen en medios institucionales de la Universidad de El Salvador.
Testimonios de pandemia: injusticia epistémica desde la experiencia escolar costarricense
Authors: Jiménez Asenjo Wendy
Published: August 2023

Para analizar los procesos de educación a distancia desarrollados durante el curso lectivo 2020 en Costa Rica, se aplicaronlos planteamientos de la injusticia epistémica a testimonios de familias, estudiantes y personal docente. Se concluye que las desigualdades estructurales y la verticalidad administrativa son evidencia de dicha injusticia.
APAKAH DEWAN KOMISARIS DAN DEWAN DIREKSI MEMPENGARUHI KINERJA KEUANGAN PERUSAHAAN PROPERTY DAN REAL ESTATE INDONESIA?
Authors: Putri Meidyna , Fakhruddin Imam , Firdaus Firdaus
Published: August 2023

Perusahaan sektor properti dan real estate tahun ke tahun mengalami penurunan valuasi saham dan kinerja keuangan. Oleh karena itu, penelitian ini bertujuan untuk mengkaji pengaruh dewan komisaris dan dewan direksi terhadap kinerja keuangan perusahaan sektor properti dan real estate di Indonesia. Penelitian ini menggunakan populasi perusahaan sektor properti dan real estate yang terdaftar di Bursa Efek Indonesia (BEI), namun pengambilan sampel berdasarkan kriteria tertentu sehingga jumlah sampel yang diambil adalah 22 perusahaan. Penelitian ini menggunakan regresi berganda sebagai analisis data, dan teknik pengumpulan data menggunakan dokumentasi melalui laman resmi perusahaan yang diteliti. Hasil penelitian menyimpulkan secara parsial hanya dewan komisaris yang berpengaruh terhadap kinerja keuangan perusahaan sektor properti dan real estate di Indonesia. Namun secara simultan, keduanya berpengaruh signifikan terhadap kinerja keuangan perusahaan. Melalui hasil penelitian ini diperoleh implikasi secara teoritis bahwa keputusan struktur manajerial akan menentukan bagaimana bisnis beroperasi ke depan. Tentunya hal ini dilakukan dalam upaya mencapai tujuan perusahaan secara maksimal, khususnya peningkatan kinerja keuangan.
Sharp inequalities for Toader mean in terms of other bivariate means
Authors: JIANG Weidong
Published: August 2023

In the paper, the author discovers the best constants $\alpha_1$, $\alpha_2$, $\alpha_3$, $\beta_1$, $\beta_2$ and $\beta_3$ for the double inequalities
\[
\alpha_1 A\left(\frac{a-b}{a+b}\right)^{2n+2} < T(a,b)-\frac{1}{4}C-\frac{3}{4}A-A\sum_{k=1}^{n-1}\frac{(\frac{1}{2},k)^2}{4((k+1)!)^2}\left(\frac{a-b}{a+b}\right)^{2k+2}<\beta_1 A\left(\frac{a-b}{a+b}\right)^{2n+2}
\]
\[
\alpha_2 A\left(\frac{a-b}{a+b}\right)^{2n+2} < T(a,b)-\frac{3}{4}\overline{C}-\frac{1}{4}A-A\sum_{k=1}^{n-1}\frac{(\frac{1}{2},k)^2}{4((k+1)!)^2}\left(\frac{a-b}{a+b}\right)^{2k+2}<\beta_2 A\left(\frac{a-b}{a+b}\right)^{2n+2}
\]
and
\[
\alpha_3 A\left(\frac{a-b}{a+b}\right)^{2n+2} < \frac{4}{5}T(a,b)+\frac{1}{5}H-A-A\sum_{k=1}^{n-1}\frac{(\frac{1}{2},k)^2}{5((k+1)!)^2}\left(\frac{a-b}{a+b}\right)^{2k+2}<\beta_3 A\left(\frac{a-b}{a+b}\right)^{2n+2}
\]
to be valid for all $a,b>0$ with $a\ne b$ and $n=1,2,\cdots$, where
\[
C\equiv C(a,b)=\frac{a^2+b^2}{a+b},\,\overline{C}\equiv\overline{C}(a,b)=\frac{2(a^2+ab+b^2)}{3(a+b)},\, A\equiv A(a,b)=\frac{a+b}{2},
\]
\[
H\equiv H(a,b) =\frac{2ab}{a+b},\quad T(a,b)=\frac2{\pi}\int_0^{\pi/2}\sqrt{a^2\cos^2\theta+b^2\sin^2\theta}\,{\rm d}\theta
\]
are respectively the contraharmonic, centroidal, arithmetic, harmonic and Toader means of two positive numbers $a$ and $b$, $ (a,n)=a(a+1)(a+2)(a+3)\cdots (a+n-1)$ denotes the shifted factorial function. As an application of the above inequalities, the author also find a new bounds for the complete elliptic integral of the second kind.