bluuebunny/crossref_metadata_2025 huggingface dataset:
A High Secured Steganalysis Using QVDHC Model
Authors: Akki Praveena , J Gitanjali , Iwendi Celestine , S Sumathy. , Waheed Amtul
Published: October 2022

Data compression plays a vital role in data security as it saves memory, transfer speed is high, easy to handle and secure. Mainly the compression techniques are categorized into two types. They are lossless, lossy data compression. The data format will be an audio, image, text or video. The main objective is to save memory of using these techniques is to save memory and to preserve data confidentiality, integrity. In this paper, a hybrid approach was proposed which combines Quotient Value Difference (QVD) with Huffman coding. These two methods are more efficient, simple to implement and provides better security to the data. The secret message is encoded using Huffman coding, while the cover image is compressed using QVD. Then the encoded data is embedded into cover image and transferred over the network to receiver. At the receiver end, the data is decompressed to obtain original message. The proposed method shows high level performance when compared to other existing methods with better quality and minimum error.
Relative Focal Mechanism Inversion and Its Application to Ridgecrest Sequence
Authors: Kuang Wenhuan , Yuan Congcong , Zhang Jie , Zhang Wei
Published: October 2022

Earthquake focal mechanisms are important for characterizing the subsurface faulting geometry and evaluating stress distributions. Existing approaches usually strive to determine the absolute focal mechanisms and may be subject to large uncertainties due to incomprehensive knowledge of the velocity model, particularly for moderate-to-small earthquakes. Alternatively, difficulties that arise from the velocity model can be largely mitigated by inverting the relative data variations in a series of earthquakes, because effects from the velocity model are systematic among all events in the vicinity. In this study, we propose a novel relative focal mechanism inversion (RFMI) method to invert the second-order variations in a series of focal mechanisms utilizing a well-constrained primary event. We test the RFMI method on both synthetic data and 251 real earthquakes (M ≥3) in the 2019 Ridgecrest sequence. The synthetic test results show that the RFMI method is robust and insusceptible to location errors (<2 km) and systematic velocity errors (5%). The real data application results demonstrate improved consistency among the inverted focal mechanisms, resulting in better characterization of the fault orientations than the Southern California Seismic Network (SCSN) focal mechanism catalog. The retrieved earthquake depths are also well correlated with the depths of the Mw 6.4 and 7.1 mainshocks. Waveform cross-correlation analysis verifies the reliability of the results. Furthermore, dynamic stress monitoring is enabled with decent resolution. The proposed RFMI method paves a new path toward achieving a rich number of reliable earthquake focal mechanisms, which will benefit the investigation of the earthquake process.
Using a genetic algorithm to model broadband regional waveforms for crustal structure in the western United States
Authors: Bhattacharyya Joydeep , Sheehan Anne F. , Tiampo Kristy , Rundle John
Published: October 2022

In this study, we analyze regional seismograms to obtain the crustal structure in the eastern Great Basin and western Colorado plateau. Adopting a forward-modeling approach, we develop a genetic algorithm (GA) based parameter search technique to constrain the one-dimensional crustal structure in these regions. The data are broadband three-component seismograms recorded at the 1994-95 IRIS PASSCAL Colorado Plateau to Great Basin experiment (CPGB) stations and supplemented by data from U.S. National Seismic Network (USNSN) stations in Utah and Nevada. We use the southwestern Wyoming mine collapse event (Mb = 5.2) that occurred on 3 February 1995 as the seismic source. We model the regional seismograms using a four-layer crustal model with constant layer parameters. Timing of teleseismic receiver functions at CPGB stations are added as an additional constraint in the modeling.

GA allows us to efficiently search the model space. A carefully chosen fitness function and a windowing scheme are added to the algorithm to prevent search stagnation. The technique is tested with synthetic data, both with and without random Gaussian noise added to it. Several separate model searches are carried out to estimate the variability of the model parameters. The average Colorado plateau crustal structure is characterized by a 40-km-thick crust with velocity increases at depths of about 10 and 25 km and a fast lower crust while the Great Basin has approximately 35-km-thick crust and a 2.9-km-thick sedimentary layer.
Velocity structure of the upper crust under the San Francisco volcanic field, Arizona
Authors: Durrani Bashir A. , Doser Diane I. , Keller G. R. , Hearn Thomas M.
Published: October 2022

In addition to traditional in-line wide-angle seismic profiles, the 1989 Pacific to Arizona Crustal Experiment (PACE-1989) included some off-line shots and seismic recorders, which, along with the data from the main profiles, provide tomographic coverage of the late Cenozoic San Francisco volcanic field. This major volcanic center is interesting because of its location on the margin of the Colorado plateau and because of the diversity of the composition of the volcanics. We employed arrival times for the Pg phase to undertake a tomographic analysis of the structure of the upper crust. The tomographic image indicates high-velocity zones at upper crustal depths under the San Francisco Mountain region. The P-wave velocities within these zones are 6% higher than the surrounding basement rocks. Although other interpretations are possible, we believe that these high-velocity regions most likely represent igneous intrusions associated with the volcanic centers that formed the San Francisco volcanic field. Geologic studies indicate that these intrusions would be of intermediate to mafic composition. Gravity data in the San Francisco volcanic field area also indicate that these high-velocity regions are coincident with high-density bodies at upper crustal depths.
Arrangement and objectives of providing patients with lung cancer with treatment during the COVID-19 pandemic in the Russian region
Authors: Startsev V. Yu. , Golubev S. V.
Published: October 2022

The operation of the oncological services of the Russian Federation were complicated by the spread of the Severe Acute Respiratory Syndrome CoronaVirus-2, which worsened the diagnosis of lung cancer and led to the reorientation of medical institutions to the anti-epidemic mode.

The aim. To evaluate the features of providing medical care for lung cancer to residents of the Magadan Region during the pandemic of COronaVIrus Disease-19 (COVID-19).

Methods. The analysis of the Magadan Region database on patients with lung cancer was carried out. The databased is filled in with the information from state statistical reporting forms No.7 and No.35. General problems of the Magadan Region healthcare system were identified using materials of publications from the Medline, CrossRef, Pubmed and Scopus databases for 2019 – 2021; the potential solutions were also suggested.

Results. The analysis of the incidence of malignant neoplasms in 2014 – 2020 yy. showed that lung tumors are in the lead among Magadan Region residents. The “rough” incidence rate of lung cancer in 2019 (58.8 per 100,000 inhabitants an increase from 2009 +20.74%) and the relative proportion of these tumors detected in 2020 in localized stages are ahead of the average values for the Russian Federation. In 2018 – 2021, the indicator of morphological verification of lung cancer and the proportion of advanced tumors continued to increase, but the one-year mortality rate was decreasing. In 2021, 10.3% of the residents of Magadan Region had low-dose computed tomography (CT) of the chest organs. 10 (1.8%) cases of lung cancer were detected. Localized lung cancer was detected in 32.5% of those cases (2020 – 24.5%, 2019 – 20.3%). The spread of the coronavirus infection has complicated work of the staff of the Magadan Region oncology service: remote medical consultations for patients living far from the regional center (Magadan) are to be developed. Insufficient number of low-dose CT machines in the medical institutions, understaffing in health facilities, insufficient use of chemotherapy in the treatment of patients with lung cancer, as well as problems of palliative care for patients with advanced stages of the tumor were identified.

Conclusion. The main problems of the oncological service of the Magadan Region are the shortage of personnel, lack of equipment and the lack of a single information field in the medical institutions. These problems of specialized medical care for patients with lung cancer will have to be solved by the regional Ministry of Health, scientific schools, and universities.
Bacterial ligands in the rehabilitation of healthcare workers after COVID-19
Authors: Kryukova N. O. , Abramova N. D. , Khromova E. A. , Khasanova A. A. , Bisheva I. V. , Skhodova S. A. , Kostinov M. P. , Baranova I. A. , Svitich O. A. , Chuchalin A. G.
Published: October 2022

Immune defense mechanisms in survivors of the COronaVIrus Disease-19 (COVID-19) and development of their rehabilitation during the pandemic both portray a great scientific and practical interest.

The aim of the study was to explore effect of Immunovac-VP-4® (I-VP-4), a vaccine based on bacterial ligands, on the clinical and airway mucosal immunity parameters, along with systemic immune response in a group of medical workers in post-COVID period and in persons who did not develop the disease.

Methods. 82 healthcare workers aged from 18 to 65 years were included in a prospective open controlled study. The participants were divided into 4 groups: groups 1 (n = 20) and 2 (n = 27) included those with a history of COVID-19, and groups 3 (n = 18) and 4 (n = 17) included those who did not have the disease. Volunteers in groups 1 and 3 received I-VP-4. Samples of oral fluid, induced sputum, nasopharyngeal and oropharyngeal mucosa scrapings, and venous blood were examined. The levels of total secretory immunoglobulin class A (sIgA) and immunoglobulin G (IgG) were determined by enzyme immunoassay. The phagocytic index (PI) of leukocytes was assessed by flow cytometry.

Results. The group of patients who did not have COVID-19 and received IVP-4 (Group 3) showed a tendency to a smaller number of COVID-19 cases, as well as some reduction in days of incapacity for work due to the acute respiratory infections (ARI). The vaccine improved airway mucosal immunity parameters and innate immune response. sIgA increased in the induced sputum (p < 0.005) and unchanged in the oropharyngeal mucosa samples in Group 1. The PI of macrophages in oral fluid doubled (p < 0.05) in this group. At the same time, those parameters decreased in Group 2. In non-infected vaccinated patients (Group 3), a significant increase of PI of blood monocytes was found on the day 90 of the study (p < 0.05). Also, a four-fold increase of PI of macrophages in oral fluid in comparison with Group 4 (p < 0.05) was noted.

Conclusion. I-VP-4 improved airway mucosal immunity mechanisms and the systemic immune response. The vaccine can be recommended for rehabilitation programs for COVID-19 survivors and for prevention of ARIs.
Shimmer
Authors: Lau Daniel
Published: October 2022

Shimmer is a collection of poems that explores the unfixed nature of self-construction through the complications of intersectionality. Throughout the text, the speaker, possessing multiple positions that share the locus of the singular unified body, navigates existing power structures in various publics in which bodies and cultures are read and deemed legible or illegible to situated hegemonic social structures. Through confessional and lyric strategies, the speaker reflects on the rituals that reify culturally informed social contracts within diverse publics.
Gallbladder agenesis, a diagnostic difficulty
Authors: Thulasilingam Kathirazhagan , Akhter Jameel
Published: October 2022

Gallbladder agenesis is a very rare presentation where surgeons were put in a situation to diagnose the same during laparoscopy for cholecystectomy or during diagnostic laparoscopy. The preoperative diagnosis of gallbladder agenesis remains a challenge to both surgeons and radiologists. Here we present a case of gall bladder agenesis in a 59-year-old male with a preoperative diagnosis of a contracted gallbladder. Agenesis was confirmed after diagnostic laparoscopy and MRCP.
Principles and challenges of quality management in primary care
Authors: Aljuhani Faisal Ahmad , Alhejji Abdullah Mohammed , Aljaloud Musaad Sulaiman , Al Shammari Turki Habib , Aljurbua Abdulelah Abdullah , Turkostany Nesma Saleh , Alhassan Abdullah Hasem , Aljuaid Nada Naji , Jereb Mashael Mohammed , Alhussain Sarah Abbas , Hutaylah Ibrahim Saleh Al
Published: October 2022

The provision of care is fragmented in the complex field of health care. In order to fulfil the needs of all groups in healthcare, quality can serve as a common paradigm. For lowering adverse events, enhancing efficiency, and improving patient satisfaction, the evaluation of quality in medical settings is becoming more and more critical. The objective of the healthcare system is to give a specific patient the best care possible from a certified practitioner in the right environment. Quality management in healthcare is the management of system designs, policies, and procedures that reduce, if not completely eradicate, harm while enhancing patient care and outcomes. Quality improvement must be ongoing in order to improve efficiency, patient safety, the delivery of evidence-based healthcare, and health outcomes. Hospitals were early adopters of quality improvement but adopting evidence-based interventions is still difficult in many primary care settings. The purpose of this research is to review the available information about principles and challenges of quality management in primary care. Relationship management, customer focus, effective leadership, employee engagement, process approach, and improvement are few of the principles of quality management. Various challenges including severely departmentalized, bureaucratic, and hierarchical structure, professional autonomy, conflicts between managers and professionals among several others are faced in primary care. Research in future can effectively contribute to addressing challenges and developing guidelines for overcoming these challenges in primary care to ensure best quality healthcare services.
DINÂMICA ESPAÇO-TEMPORAL DA COBERTURA VEGETAL E USO DA TERRA NOS ASSENTAMENTOS FACÃO ESTADUAL E FACÃO/BOM JARDIM - CÁCERES-MT, BRASIL
Authors: Mendes Marcílio Ferreira , Neves Sandra Mara Alves da Silva , Kreitlow Jesã Pereira
Published: October 2022

O planejamento do uso da terra nos assentamentos rurais é elaborado no âmbito do Plano de Desenvolvimento do Assentamento (PDA), visando desenvolvimento socioeconômico dos Agricultores familiares e a sustentabilidade ambiental. O objetivo deste trabalho é analisar a dinâmica espaço-temporal da cobertura vegetal e uso da terra dos assentamentos Facão Estadual e Facão/Bom Jardim, Cáceres-MT. Para a elaboração da análise espaço-temporal dos assentamentos foram utilizadas imagens dos satélites Landsat 5, dos anos de 1986, 1996 e 2006 e Landsat 8 de 2016 e Sistema de Informação Geográfica. Foi calculado o índice de transformação antrópica (ITA) dos anos de estudo. Constatou-se que houve diminuição da vegetação nativa devido ao avanço da criação de gado, sendo que esta prática ocorre nas áreas de estudo antes destas constituírem em assentamentos e o ITA dos assentamentos em 1984 era pouco degradado, sendo que a partir de 1996 passou a regular no assentamento Facão estadual e nos anos seguintes para o Facão/Bom Jardim. Concluiu-se que nos assentamentos estudados predomina a vegetação de Savana arborizada com a presença de Savana florestada que estão sendo suprimidas devido ao crescimento da Pastagem plantada para manutenção do gado de leiteiro e de corte, propiciando a alteração da paisagem e implicando na redução da biodiversidade do Cerrado nas áreas investigadas.
Análise do campo térmico e higrométrico no campus da Universidade Federal do Espírito Santo, Vitória (ES)
Authors: Do Nascimento Fabricio Holanda , Dos Santos Fernanda Barboza , Jaques Jonatha Liprandi
Published: October 2022

O presente estudo tem por objetivo analisar a temperatura e umidade relativa do ar no campus da Universidade Federal do Espírito Santo, localizado no bairro Goiabeiras, Vitória (ES). A pesquisa realizou-se em dois horários distintos: 9 e 15 horas entre os dias 08 e 09 de abril de 2015. Foram realizadas coletas de dados de temperatura do ar e umidade relativa do ar em 18 pontos no interior do campus, através de dois relógios Termo Higrômetros de leitura direta tipo MINIPA-MT214, em abrigos confeccionados a partir de cano de PVC, associados à leitura de um ponto fixo e um transecto móvel com registro a cada 10 minutos. Os resultados alcançados na pesquisa permitiram um conjunto de conclusões bastante surpreendentes, pois se verificou uma diferença térmica e higrométrica relativamente grande nos diferentes pontos pesquisados, considerando que o espaço lócus da pesquisa compreende uma área relativamente pequena do campus. Ao final, aferiu-se que os resultados corroboram e dialogam com as principais teorias das correntes que identificam as ações humanas como causas de significativas transformações no comportamento dos elementos da atmosfera, em especial da temperatura do ar e da umidade relativa do ar.
LINGUAGEM CARTOGRÁFICA: A GEOTECNOLOGIA MOOVIT COMO SUPORTE PARA O DESENVOLVIMENTO DO PENSAMENTO ESPACIAL
Authors: Vasconcelos Junior José Luiz Ferreira , Pompeu Cristian Lima
Published: October 2022

As geotecnologias expõem novas possibilidades de analisar o espaço que se apresenta cotidianamente, trabalhá-las no ensino e aprendizagem de Geografia pode gerar resultados positivos. Neste contexto, o presente estudo teve como objetivo propor o uso da Geotecnologia Moovit no ensino de Geografia tendo como base nos Parâmetros Curriculares Nacionais (1998). A problemática do trabalho buscava responder qual a contribuição da Geotecnologia Moovit para o ensino de Geografia? Os resultados obtidos mostram que os alunos são favoráveis a ferramentas inovadoras que trabalhem os conhecimentos da sala de aula com problemas do cotidiano. Assim, é possível inferir que o uso de geotecnologias, como o Moovit, no ensino e aprendizagem de Geografia contribui de forma satisfatória na formação de um discente com um pensamento espacial mais crítico e amplo.
MOBILIDADE ACADÊMICA INTERNACIONAL: UM ESTUDO EXPLORATÓRIO NA CIDADE DE LAJEADO/RS, NA PERSPECTIVA DE CHEGADA
Authors: Cazarotto Rosmari Terezinha , Sindelar Fernanda Cristina Wiebusch , Radavelli Marina
Published: October 2022

O número de estudantes que participam de programas de mobilidade acadêmica internacional, aumentou significativamente nas últimas décadas. Este estudo, de caráter exploratório, tem como objetivo compreender o fluxo internacional de estudantes da educação superior, na perspectiva de quem chega a Lajeado, uma cidade média situada no interior do Rio Grande do Sul. Para tal, articulam-se informações de dados quantitativos, obtidos em bancos de dados oficiais, seguidas de uma abordagem qualitativa a partir de aplicação de questionário a estudantes em mobilidade acadêmica na Univates, em 2019. A análise dos resultados evidenciou que os estudantes estrangeiros são provenientes de diferentes países e continentes, com destaque para os colombianos, para o sexo feminino e para uma média de idade de 23 anos. Essa realidade contribui com as dinâmicas de circulação intercultural na cidade.
As pequenas cidades da Amazônia Setentrional: um estudo sobre a cidade de Caracaraí/RR
Authors: Silva Talita Alves da , Rosa Filho Artur
Published: October 2022

A presente pesquisa se propôs a analisar o crescimento temporal da malha urbana de Caracaraí-RR. A preocupação em realizar essa análise se deve ao fato de Caracaraí se enquadrar na classificação das pequenas cidades, e, ao mesmo tempo, ser um palco interessante para as investigações sobre o urbano. O estudo iniciou-se, primeiramente, com pesquisa bibliográfica; posteriormente houve a pesquisa documental e a observação do objeto de estudo. A previsão das ações para cada uma dessas fases buscava responder aos objetivos específicos: traçar uma periodização dos agentes produtores de seu espaço urbano, considerando os eventos de cada período de sua Geo-história, e mapear o processo de expansão urbana da cidade. Os resultados demonstram que a expansão urbana da cidade tem como marco inicial a década de 1970, quando esse espaço recebeu um plano de urbanização. Considerando os proprietários dos meios de produção, os proprietários fundiários, os promotores imobiliários, o Estado e os grupos sociais excluídos, houve e ainda há a presença de alguns desses agentes na cidade, tendo estes interferência na modelagem de seu espaço urbano. Espera-se que as discussões retratadas nesta pesquisa possam contribuir para a relevância das discussões sobre pequenas cidades, bem como suas dinâmicas urbanas e sua importância no cenário da rede urbana brasileira.
Asociación entre síndrome de Guillain-Barré y COVID-19 pediátrico. Informe de caso
Authors: Manzanera-Ornelas Diana Alejandra , Aguirre-García Michel Iveth , Romero-Jacobo Ginna Mariana , Quintero-Jurado Gloria Liliana , Saad-Manzanera María Isabel , Guerrero-Lara María Fernanda
Published: October 2022

ANTECEDENTES: El 11 de marzo del 2020 se declaró como pandemia a la infección por SARS-CoV-2, estableciendo principalmente clínica respiratoria y gastrointestinal. La infección en pacientes pediátricos ha tenido una variedad importante de sintomatologías, destacando las alteraciones neurológicas, así como un aumento de informes por síndrome de Guillain-Barré (SGB); sin embargo, estos últimos son escasos.CASO CLÍNICO: Niño de 10 años de edad, el cual inició con debilidad de extremidades inferiores, tos productiva y fiebre; con antecedente de hospitalización a los 2 años por Síndrome de Guillain-Barré durante 15 días, con recuperación completa. Al llegar a nuestra unidad se realizó Tomografía Axial Computarizada de tórax con datos sugestivos de COVID-19, se solicitó RT-PCR para SARS-Cov-2 con resultado positivo, además de una electromiografía en la que se obtuvieron resultados concordantes con una polineuropatía desmielinizante compatibles con variante de neuropatía axonal aguda motora en las cuatro extremidades. A pesar del manejo con gammaglobulina y plasmaféresis el paciente falleció.CONCLUSIÓN: El diagnóstico y tratamiento del Síndrome de Guillain-Barré relacionado con COVID-19 en pacientes pediátricos se ha mostrado como un verdadero reto al disponer de pocos reportes en la bibliografía, por lo que la importancia de la revisión del presente caso es tener en mente la diversidad de manifestaciones que se presentan en la infección por COVID-19 y contemplarlo en el diagnóstico diferencial de las encefalitis y cuadros infecciosos con manifestaciones neurológicas.
High Analytics Information Technologies: A Patent-Based Cooperation Network Analysis
Authors: Pigola Angelica , Costa Priscila Rezende Da , Carvalho Luisa Margarida  Cagica , Porto Geciane Silveira , Paulo Alex Fabianne De
Published: October 2022

Technologies that involve great part of firms are those based on high analytics information (HAI) technologies as an essential resource for operating different types of businesses. Through HAI patents analysis filed between 2000 and 2020 in the main patent offices in the world, this study aims to understand whether assignees have been developing HAI technologies in cooperation and emerging HAI technologies using social network analysis (SNA). Findings show that HAI patents assignees prioritize half of their developments in R&D internally, and the other half in partnership with other companies, primarily. It is also identified that cooperation relations are between organizations with the same nationality, especially those in South Korean and North American. In addition, United States is the main market of interest even the number of HAI technologies patented have been decreasing over the last five years. Despite this context, the identification of relational capabilities between assignees and the reconfiguration of resources, as a dynamic capability, is evidenced in HAI technologies development. Findings may support to identify HAI that still emerge in different industries, especially in service industry and support strategic Research & Development (R&D) decision-making processes to prioritize investments, identify new partnerships to innovate, or collaborate to develop public policies to foster new HAI technologies development.
Evaluation of Factors Affecting the Quality of Virtual Education During the COVID-19 Pandemic
Authors: Seddighi Narjes , Bolbolizade Pedram , Vatanparast Dabanlou Mohamadamin , Davaridolatabadi Nasrin
Published: October 2022

The prevalence of Corona virus Disease 2019 (COVID-19) has affected the university education system. Due to the development of technology in recent decades and the need for social distance to prevent the spread of the disease and to prevent interruptions in student education, education has changed to virtual. Considering the importance of education and its decisive role in improving the academic level of students, we tried to review the challenges of virtual education and the factors affecting its quality. This review study was performed by searching databases such: as Pubmed, Scopus, SID, and Magiran using keywords including virtual teaching, virtual learning, COVID-19, and Medical Sciences and limiting the search to the keywords in the title and abstract and also according to PRISMA guidelines. In the present study, the advantages and disadvantages of e-learning were investigated. Findings showed that the factors affecting the quality of e-learning are classified into four main sections, which include: the existence of appropriate infrastructure, Class control and administration, Necessary training for using software for professors and students, and the Proportion of the volume of taught content with its evaluation. One of the most important disadvantages of e-learning in the past year is the lack of proper infrastructure for training and exams, high internet interruption, the impossibility of student interaction, and the large volume of content. Due to the existence of barriers to the formation of classes in person, it is possible to help increase the educational quality of students and advance learning by using the necessary and appropriate measures in the correct use of virtual education and increasing the quality of the required infrastructure.
Nursing University Students' Experience of Online Education in COVID-19 Pandemic: A Content Analytic Study
Authors: Broujeni Razieh Beigi , Khademi Zahra , Ahmadi Zakieh
Published: October 2022

COVID-19 pandemic and the consequent online mode of education have challenged the national educational system and higher education. Thus, the present research aimed to explore students' experience of the advantages and disadvantages of online education at Bandar Abbas University of medical sciences during the pandemic. The present qualitative research conducted a content analysis of 26 nursing students' experiences. The sampling method was purposive. Unstructured face-to-face interviews were conducted with participants of the study to collect the required data. The interview protocol was followed. The required social distance was kept, and the ethical code was adhered to. The participants were interviewed as already arranged at a place of convenience. The interviews took between 40 and 60 minutes, depending on the immediate condition. The data collection continued until data saturation. The data analysis led to the extraction of 5 themes and 8 categories, including teacher-student miscommunication, student-student miscommunication, evaluation issues, anxiety, distancing from active learning, materials/sources, lack of physical attendance, non-educational activities, and 22 subcategories. The present findings could help professors and education authorities to better understand students' expected learning and the challenges of online education. They could, thus, be better aware of the existing barriers and could better plan to remove them.
A Case Report of a Rare Huge Ureteral Fibroepithelial Polyp: Challenges and Clinical Management
Authors: Rezayat Alireza Akhavan , Yarahmadi Amir , Aghaee Atena , Zeynali Farid , Soltani Salman
Published: October 2022

Ureteral  fibroepithelial  polyps  (UFPs)  are  rare  abnormality  that  may  cause  ureteral obstruction.  Herein,  we  report  a  35-  year-  old  woman  with  flank  pain,  dysuria, frequency and transient total gross hematuria. A mass in the right ureter was reported on imaging and in endoscopic evaluation, small polypoid mass protruding from the right ureteral orifice in the bladder, and a huge ureteral mass originating from proximal ureter was observed. A right subcostal flank incision was done, a huge polypoid mass with a segment of ureteral was excised, and end-to-end anastomosis of the ureter was done. Histopathological examination showed a UFP without malignancy.
Congenital Insensitivity to Pain with Anhidrosis (CIPA) Syndrome; A Rare Genetic Disorder Case Story
Authors: Nafei Zahra , Jafari Marjan
Published: October 2022

Congenital insensitivity to pain with anhidrosis (CIPA) is the subtype four of hereditary sensory and autonomic neuropathy (HASN IV), caused by a defect in the NTRK1 gene and presenting early in life. We report a ten-year-old boy with gait problems and an inability to put weight on his feet. Four days before the visit, a trauma entered his right knee during a football match. He had swelling and erythema in his right knee and multiple scars on his torso and limbs. Magnetic resonance imaging (MRI) offered osteomyelitis and soft tissue periosteal abscess. The patient underwent an operation, and based on the pathology results, myositis ossificans (MO) was reported. Moreover, he was treated with antibiotics and supportive measures and was discharged with partial recovery. According to our knowledge, this is the first report of MO due to recurrent trauma in children with CIPA syndrome.
The Effects of Preimplantation Genetic Testing for Aneuploidy (PGT-A) on Patient-Important Outcomes in Embryo Transfer Cases: A Meta-Analysis
Authors: Sordia-Hernandez Luis H. , Morales-Martinez Felipe A. , González-Colmenero Fernando Díaz , Flores-Rodriguez Andrea , Leyva-Camacho Paloma C. , Sordia-Piñeyro Maria Ofelia , Valdés-Martínez Otto H. , García-Luna Selene M. , Rodríguez-Guajardo René , Sordia-Piñeyro Luis H.
Published: October 2022

Background: The aim of this study was to evaluate the effect of preimplantation genetic testing for aneuploidy (PGT‐A) on patient-important reproductive outcomes after in vitro fertilization (IVF).
Methods: Randomized and non-randomized studies have been sought in Ovid, MEDLINE, EMBASE, Web of Science, Scopus, and Cochrane Central Register of Controlled Trials since each database’s inception through May 2021. Main keywords used for the search strategy included "Embryo transfer", "In vitro fertilization", "DNA sequencing", and "Comparative genome hybridization". Studies were screened independently and in duplicate.
Results: Ten studies were finally analyzed, representing a total of 2630 embryo transfers. The pooled OR for live birth rates were 1.45 (95%CI 0.24-8.78, I2 96%) and 1.66 (95%PI 0.15-18.01, 95%CI 0.98-2.83, I2 81%) derived from the NRSIs and the RCTs, respectively, in which the miscarriage rate were 1.25 (95%CI 0.19-8.33, I2 70%) and 0.57 (95%PI 0.06-5.34, 95%CI 0.27-1.21, I2 53%), and clinical pregnancy rates were 3.08 (95%CI 2.22-4.29, I2 0%) and 1.43 (95%PI 0.38-5.42, 95%CI 0.96-2.13, I2 68%). Influence analyses showed a greater treatment effect when excluding studies without patients at advanced maternal age.
Conclusion: There seems to be no significant difference in reproductive outcomes when using PGT-A in the general population; however, the procedure seems advantageous for patients at advanced maternal age. Nevertheless, this warrants caution when recommending the procedure to all couples seeking ART, as the current possible benefits may not justify the additional costs for all groups of patients.
Frequency, Risk Factors, and Pregnancy Outcomes in Cases with Placenta Accreta Spectrum Disorder: A Case-Control Study
Authors: Tadayon Mitra , Javadifar Nahid , Dastoorpoor Maryam , Shahbazian Nahid
Published: October 2022

Background: Placenta accreta spectrum (PAS) disorder is an important life-threatening problem. The purpose of the current study was to determine the frequency, risk factors, and pregnancy outcomes of PAS in our population.
Methods: This is a case-control study using the data from a main tertiary referral university hospital in Ahvaz, southwest of Iran. The sample included 187 cases diagnosed with placenta accreta spectrum from 2015 to 2019 and 552 controls without PAS. A multivariable logistic regression model was used to find independent risk factors with 95% confidence interval. Pregnancy outcomes were evaluated using chi-square, t-test, and Mann-Whitney U test and p<0.05 were considered statistically significant.
Results: The frequency of PAS during the study period was 3.7/1000 deliveries (0.37%). It was found that multiparity (≥3 deliveries, OR=2.05: 95%CI:1.21-3.47) and multigravidity (≥3 deliveries, OR=2.98: 95%CI:1.55-5.72), prior cesarean delivery (OR=52.55: 95%CI:19.73-139.96), and placenta previa (OR=27.48: 95%CI: 9.62-78.5) are the independent risk factors of PAS. Complications and morbidity associated with PAS included hysterectomy (60.4% vs. 0.7%, p<0.001), cystostomy (24.1% vs. 0.2%, p<0.001), the need for blood transfusion (73.7% vs. 1.4%, p< 0.001), intensive care unit admission of mother (42.8% vs. 0.2%, p<0.001), duration of hospitalization (7.52±6.34 vs. 1.97±1.83, p<0.001), preterm birth <37 weeks (61.4% vs. 16.8%, p<0.001), and perinatal mortality (7.4% vs. 1.8%, p<0.001) which manifested statistically significant values.
Conclusion: The frequency of PAS is similar to other populations.  Prior cesarean delivery, placenta previa, multigravidity, and multiparity were independent risk factors and also perinatal hysterectomy and preterm birth were the most important complications.
Apparent Homozygosity for a gr/gr AZFc Deletion in A 47,XYY Man with Oligozoospermia and Secondary Infertility
Authors: J. Bunyan David J. Bunyan , Saran Mili , I Hobbs James , J Anderson David , J. Duncan-Flavell Philippa , J Howarth Rachel , L.A. Callaway Jonathan , N MacPherson James
Published: October 2022

Background: Approximately 1 in 1000 men have a 47,XYY karyotype. Previous publications have presented cases of infertile XYY men and have suggested that the additional Y chromosome may cause disrupted meiosis leading to sperm apoptosis. The purpose of the current study was to determine whether XYY men are over-represented in infertility cohorts.
 
Methods: In this paper, an ongoing infertility cohort was evaluated for Y chromosome microdeletions using the MLPA technique and the data from the first 2000 referrals were recorded. Moreover, the MLPA technique detected 47,XYY karyotypes.
Results: Four XYY individuals were identified within the cohort. One of the four XYY men was shown to have an apparent gr/gr partial AZFc deletion on both Y chromosomes while Sertoli cell only syndrome was detected in another case. The other two cases (out of 2000) might, therefore, represent an incidental finding. 
Conclusion: The gr/gr deletion is not detectable by the multiplex PCR method; therefore, there might be additional explanations for the fertility problems of infertile XYY men reported in previously published articles. It seems that among other cases, their XYY karyotype may be coincidental, rather than causative of their fertility issues.
Mechanical Circulatory Assist Devices: Time for More Attention by Iranian Cardiologists
Authors: Ashraf Haleh , Taghavi Sepideh , Navid Hossein
Published: October 2022

The. Article Abstract is not available.
Correlations Between the Circulating Level of Cell-Derived Microparticles and Surgical Variables in Heart Valve Surgery with Cardiopulmonary Bypass
Authors: Abdolalian Mehrnaz , Khalaf-Adeli Elham , Yari Fatemeh , Hosseini Saeid , Bakhshandeh Hooman
Published: October 2022

Background: Cell-derived microparticles (MPs) as membrane vesicles are procoagulant. They play a role in surgical hemostasis. In this study, the correlations between the circulating level of cell-derived MPs and surgical variables in heart valve surgery were investigated.
Methods: The present prospective case-series study was conducted in Rajaie Cardiovascular Medical and Research Center from January through March 2021. Forty patients undergoing heart valve surgery with cardiopulmonary bypass (CPB) were enrolled. Before the induction of anesthesia and 30 minutes after the administration of protamine sulfate, venous blood samples were collected. After MP isolation, the concentration of MPs was determined via the Bradford method. Flow cytometry analysis was performed to determine the MP count and phenotype. Intraoperative variables and postoperative routine coagulation tests were defined as surgical variables. Postoperative coagulopathy was defined as an activated partial thromboplastin time (aPTT) ≥48 seconds or an international normalized ratio (INR) >1.5.
Results: The total concentration of MPs and the MP count increased significantly after surgery compared with before surgery. The postoperative concentration of MPs was positively correlated with the CPB time (P=0.030, ρ=0.40). The preoperative concentration of MPs was significantly lower in patients with higher postoperative aPTT and INR (P=0.003, Ρ= −0.50 and P=0.020, Ρ= −0.40, respectively). In multivariate logistic regression analysis, the preoperative MP concentration (OR, 1.00; 95% CI, 1.00 to 1.01; P=0.017) was considered a risk factor for postoperative coagulopathy.
Conclusion: The levels of MPs, especially platelet-derived MPs, rose after surgery, in correlation with the CPB time. Given the role of MPs in the induction of coagulation and inflammation, they can be considered therapeutic goals for preventing postoperative complications. In addition, the preoperative levels of MPs are a risk factor for predicting the occurrence of postoperative coagulopathy in heart valve surgery.
Degradação de ibuprofeno por eletrólise sob plasma elétrico de alta tensão e baixa corrente, com sistema multieletrodos
Authors: Freitas Rodrigo Marlière de , Reis Efraim Lázaro , Reis César , Moreira José Flávio , Matias Alexsandro Antônio , Damasceno Odilaine Inácio de Carvalho
Published: October 2022

Foi feita a degradação do fármaco Ibuprofeno, por meio de eletrólise sob plasma elétrico de alta tensão e baixa corrente. Este é um processo eletrolítico não faradáico, onde o plasma é sustentado por descargas entre o ânodo e o eletrólito líquido no seu entorno, causando efeitos físicos e químicos variados, produzindo espécies químicas radicalares e moleculares, todos de alta reatividade. Na célula eletroquímica utilizada os ânodos de fios de platina ficam expostos cerca de 1,5 mm na solução enquanto o cátodo de grafite espectroscópico fica envolto por um tubo de plástico com furos laterais. A diferença de potencial foi mantida em 625 volts nos experimentos de medidas temporais de produção de H2O2, observando-se um aumento exponencial na concentração em função do tempo de aplicação do plasma, tendendo à estabilidade após 40 minutos. A geração de H2O2 de acordo com o número de ânodos adicionados não é linear, aparentemente devido a pequenas diferenças dos ânodos de platina. Para o estudo da degradação do Ibuprofesno foi feito um planejamento fatorial com as variáveis eletrólito, número de ânodos e diferença de potencial. O acompanhamento da degradação foi realizado por varreduras espectrais no ultravioleta, nos tempos de 0, 30 e 60 minutos após a ignição do plasma. Ocorreu uma redução substancial da banda de absorção do ibuprofeno em 222 nm. Para as soluções em que se trabalhou com dois eletrodos, apareceu uma banda de absorção em 210 nm. Esta banda desapareceu após 60 minutos de aplicação do plasma, aparentemente devido a existência de uma espécie intermediária facilmente degradável, uma vez que a banda não aparece quando se utiliza mais eletrodos. Pelas medições de Carbono Orgânico Total obteve-se degradações acima de 90% após 60 minutos de aplicação do plasma, para algumas soluções, provavelmente devido a um efeito sinérgico, pela combinação de variáveis destas soluções no planejamento.
Plant-based products: potential, production technology and challenges
Authors: Costa Isabella Maciel , Barbosa Cosme Damião , Silva Nayana Hayss Araújo da
Published: October 2022

Consumers have become more interested in diets that provide health benefits and contain plant-based products. Therefore, the food industry has observed the demands and developed plant-based products. Vegetable extracts are water-soluble extracts based on vegetables, legumes, fruits, grains, cereals, pseudocereals, oilseeds or nuts that present different composition and sensory characteristics, depending on the raw material used. Meat substitutes, such as tofu and soy protein, have long been consumed by the population. However, nowadays there is a market demand for plant-based products that resemble animal products in taste, texture and appearance. One of the biggest challenges for the food industry is the development of new innovative products which do not contain ingredients of animal origin and contain nutritional support to act as a replacement for the daily consumption of the population. This work aimed to evaluate the possibility of elaborating plant-based products, the technologies used in the process, and the challenges involved. The study was characterized as a qualitative and bibliographic literature research. Scientific articles, monographs and reviews published between 2018 and 2022 were selected. Studies showed that technological innovations in the food industry produce plant extracts with better sensory characteristics and an increase in acceptability using additives and ingredients that provide a pleasant flavor and aroma. Thus, it was observed that plant-based products are promising and meet market demands, and new technologies have been used to improve their sensory characteristics. However, it is necessary to pay attention to the adequate supply of nutrients essential for the proper functioning of the body through a balanced diet recommended by nutrition professionals.
Interferometer for Monitoring Convex Hyperbolic Surfaces of Small Diameters
Authors: Timashova L.N. , Kulakova N.N.
Published: October 2022

We used Fourier transforms to perform a theoretical analysis of how the process of interference pattern formation in a laboratory-scale Fizeau laser interferometer is affected by the error in the working wave front. The interferometer is designed to monitor convex hyperbolic surfaces characterised by small diameters and low aperture angles. We indicate their application scope. The interferometer consists of a laser illuminator, a microlens, a beam splitter, that is, a thin plane-parallel plate with a semitransparent coating on its front surface, and a screen. A thin translucent plate located perpendicular to the line connecting the geometric foci of the hyperbolic surface acts as a separator and a reference simultaneously. The paper provides the main equations describing the wave aberration of the working branch and the position of optical elements in the interferometer design. We present an example of computing aberration in the working branch of the interferometer. This calculation reveals that aberrations in the thin plane-parallel plate can be discarded at low aperture angles. The interferometer forms a high-precision optical surface map, that is, interference band distortion caused by the interferometer error does not exceed 0.1 of the distortion caused by the error inherent to the surface being monitored. The interferometer provides highly accurate measurement of hyperbolic surfaces while featuring an obviously simple design
Adaptive Approach to Implementation of Complex Simulation Systems
Authors: Gordin M.V. , Ivanova G.S. , Proletarsky A.V. , Fetisov M.V.
Published: October 2022

The paper presents an approach potentially capable of implementing efficient import substitution in the field of modern software systems for simulating and designing manufacturing processes in various industries, as well as of compensating for the destruction of international connections that made it possible to build efficient labor division structures for developing modern software systems. To solve these problems, we propose to implement an adaptive simulation system than can adjust to different domains by means of considerable automation concerning development of domain-specific programming languages describing models in the relevant subject areas. We also propose to split development into the following competence and responsibility zones: developing an extensible core for the adaptive simulation system and shared language and visual (graphic) components; developing domain-specific extensions, which may include both language and visual (graphic) components; populating a specific extension with a database of industry standards; developing a manufacturing model specifically. Using a shared platform represented by the adaptive simulation system allows for reusing extensions from different domains so as to form complex simulations, resulting in possible technological breakthroughs at the juxtaposition of various industries. The paper also briefly describes certain risks associated with the implementation and maintenance of complex simulation systems in the Russian Federation. We consider alternatives to the solutions proposed
„Fail better”, czyli jak poprawić improwizację
Authors: Żaglewska Agata
Published: October 2022

W tym artykule wskazuję związki filomackiej poezji okolicznościowej z improwizacją poetycką. Na podstawie analizy autografów dwóch wybranych utworów – Jambu dla Jana II Tomasza Zana i Odezwy spod stołu Teodora Łozińskiego – uzasadniam tezę, że jamby przedstawiane podczas imieninowych fet to przykłady improwizacji w piśmie. Analizowane utwory intensyfikują dwie najbardziej charakterystyczne cechy jambografii – zawrotną szybkość tworzenia (Zan) i wynikające z niej niedopracowanie, bylejakość wypowiedzi poetyckiej (Łoziński). Zwracam uwagę na uzupełnianie się kodów lingwistycznych i materialnych, tj. wzmożenie podanych cech zawartych w warstwie słownej utworów poprzez sposób ich zapisu w autografach. W części drugiej artykułu zastanawiam się nad możliwościami wprowadzania modyfikacji do utworów o improwizowanym charakterze – wprowa­dzam kategorię „poprawiania przez powtórzenie” i opisuję ją, odwołując się zarówno do Jambu dla Jana II i Odezwy spod stołu, jak i do innych tekstów pozostałych po filomackich fetach.
Traces of improvisation in "Jedyne wyjście" by Witkacy
Authors: Bocheński Tomasz
Published: October 2022

In the article I have analysed the concept of improvisation recorded in Jedyne wyjście by Witkacy. He described the notion as unconstrained variation-based creation flowing from an inspired vision. Witkacy considered vision as the most fundamental source element of artistic theory and creative practice. I have also analysed the traces of improvisation in the manuscript of Jedyne wyjście and I have discussed the play between amplifications and visions recorded in the improvised fragments.