bluuebunny/crossref_metadata_2025 huggingface dataset:
AN An Enhanced Differential Homomorphic Model using N-Prime Scheme for Privacy Preservation
Authors: Sanni Hafiz O. , Isiaka Rafiu M. , Babatunde Akinbowale N. , Jimoh Muhammed K.
Published: April 2023

In preserving individual privacy in data publishing, several efforts have been made by scholars globally to develop an individual privacy preserving model and hybridized models which harness the strength of the individual model to increase privacy preservation in data Publishing (PPDP). The Differential homomorphic model (DHM) was among the hybridized models developed that combine differential and homomorphic models. Though is one of the state of the art hybridization methods for privacy preservation because of the Differential model and Homomorphic model strengths of the two hybridized models which are the ability to prevent composition problems and database attacks respectively. However, applying this model is challenging because of the high computational complexities due to the modular exponentiation problem available in pailler encryption scheme used in DHM. In this research, an N-PRIME homomorphic encryption scheme was proposed to replace the Pailler encryption scheme in the differential homomorphic model (DHM). The designed model was 51% faster than the existing model (Differential Homomorphic Model) in terms of computation time and 48.5% faster when generating the graphical data set, though the designed model consumed 4% more storage space than the existing model.
STAKEHOLDER IDENTIFICATION: A STUDY ON PERFOMANCE AUDIT CONCEPT AND ORGANIZATIONAL EXCELLENCE
Authors: SAHERTİAN Rachel , JATİNİNGSİH Dyah Ekaari Sekar
Published: April 2023

This study aims to examine the concept of performance audit and organizational excellence using a stakeholder perspective. This research was conducted in a service organization by observing and collecting information from informant covering directors, shareholders, and employees. This research is qualitative, using semi-structured interviews with a constructionist approach. Based on the results of the analysis that has been carried out, it is found that there are no significant differences of opinion among stakeholders regarding the concept of performance auditing in the achievement of organizational excellence, and there are differences of opinion regarding the magnitude of the contribution of performance audits given in an effort to achieve organizational excellence, namely 5–10%, 80–90%, and 95–95%. This study uses stakeholder theory to identify stakeholders in the object of research, and the results show that there is a dominant role, namely, the dominant stakeholder which plays the role of customer. In this case, the organization relies on significant stakeholders to achieve organizational excellence.
Comparison between the Levels of N Terminal Pro-Brain Natriuretic Peptide and Troponin I to Predict Left Ventricular Ejection Fraction in Patients Presenting with First ST-Elevation Myocardial Infarction
Authors: Sheikh Kaleem Ullah , Farooq Amna , Sarfaraz Abeer , Sarfaraz Sana , Athar Sadaf , Zehra Aemon
Published: April 2023

Objectives: To compare the levels of N Terminal- ProBrain natriuretic peptide (NT-proBNP) and Troponin I (Trop I) to predict left ventricular ejection fraction (LVEF) in patients presenting with first ST-elevation myocardial infarction (STEMI).
Methodology: A cross-sectional study was carried out in Cardiology department of a tertiary care hospital from June to November 2021. A total of 150 patients who presented at emergency department with first STEMI and underwent primary percutaneous coronary intervention (PCI) were included. The patient’s second set of troponin I and NT-proBNP were collected during hospitalization. Echocardiography was done. Left ventricular function was assessed using modified Simpson’s method. For data analysis, SPSS 21 was used.
Results: The mean age was 60.60±11.1 years. There were 76% males, 53% hypertensive, 44% diabetic, 14% smokers with the most prominent type of myocardial infarction being anterior wall myocardial infarction accounting for 76.7%. Mean Trop I was 12.2±6.81 ng/ml, 9.5±8.63 ng/ml and 3.0±5.41 ng/ml for LVEF≤40%, 41-49% and >50% respectively while NT-proBNP was 7136.4±7.97pmol/l, 2328.9±3498.6pmol/l and 441±283.6pmol/l for LVEF ≤40%, 41-49%, and >50% respectively. We found a significant mean difference for Trop I (p=0.000) and NT-proBNP (p=0.0001). There was an inverse significant relationship of left ventricular ejection fraction with Trop I (r=-0.290, p=0.000) and NT- proBNP (r=-0.388, p=0.000).
Conclusion: In comparison to Troponin I, NT-proBNP serves as a better marker to predict LVEF in patients presenting with first STEMI.
Evaluation of the Quantity and Duration of Junctional Rhythm during Successful Radiofrequency Ablation among Patients with Atrioventricular Nodal Re-Entry Tachycardia
Authors: Butt Usman Mahmood , Saleem Imran , Shahid Hafiz Abdul Mannan , Hassan Waqar , Dar Muhammad Ashraf , Akram Zubair
Published: April 2023

Objectives: To evaluate the quantity and duration of junctional rhythm during radiofrequency ablation among atrioventricular nodal reentry tachycardia (AVRNT) patients.
Methodology: A Cross sectional study was conducted at Punjab Institute of cardiology from May – July, 2022. Ablations of slow pathway were executed on 50 patients who fulfilled the inclusion criteria using ablation catheters of 4-mm tip. Power output was kept between 35- 40 Watt with a temperature control at 60 °C depending upon the occurrence of junctional rhythm. The target end points of radio frequency ablation (RFA) were inability to either induce or spontaneously demonstrate clinical tachycardia. Presence of more than one atrio-ventricular (AV) nodal echo beat was the criteria to continue further ablations as it was considered indicator residual slow pathway. Data was entered in SPSS software version 21.0 and were presented as mean ± SD were used.
Results: The mean age of the patients was 36.50 ± 7.129 years. Ablation power was titrated between 35-40 watts (Mean 39.6 ± 1.37). The average amount of junctional beats in each patient was 57.34 ± 9.71 (73-38) with mean duration of junctional rhythm was 29.20 ± 3.47 sec. Successful ablation mean was 54.25 + 8.45 as compared to unsuccessful attempts of 44.32 ± 5.77 and was statistically significant (p<0.001).
Conclusion: The study concluded that RFA had high success rate and a low recurrence rate with less complication. Junctional rhythm is a sensitive predictor of successful ablation and is a safe and effective way of permanent termination of AVNRT.
12-Lead Electrocardiogram - A Valuable Tool in Temporary Cardiac Pacing Management
Authors: Naqvi Syed Haseeb Raza
Published: April 2023

Inadvertent malposition of pacing leads is a recognized complication of temporary cardiac pacing procedure, which can be fatal particularly if lead placement is in the left ventricular (LV) cavity because of the risk of thromboembolic events.1 Malposition leads can be either due to unrecognized congenital heart defects including atrial or ventricular septal defects, patent foramen ovale or due to iatrogenic perforation of interventricular septum but sometimes it may be due to faulty insertion via trans-arterial instead of trans-venous access.2
 
References

Gupta S, Annamalaisamy R, Coupe M. Misplacement of temporary pacing wire into the left ventricle via an anomalous vein. Hellenic J Cardiol. 2010;51(2):175-7.
Garg N, Moorthy N. Inadvertent temporary pacemaker lead placement in aortic sinus. Heart views: the official journal of the Gulf Heart Association. 2013;14(4):182.
Electrocardiogram Changes in Patients with Positive Troponin I Presenting with Non-ST-Elevation Myocardial Infarction
Authors: Khowaja Raheela , Khowaja Aamir , Khan Waqar , Ammar Ali , Khursheed Munawar , Sial Jawaid Akbar
Published: April 2023

Objectives: Unlike “ST-segment elevation myocardial infarction (STEMI)”, there is a wide spectrum of ECG changes for Non-STEMI (NSTEMI) patients with varying prognostic implications. Therefore, the purpose of this study was to determine the frequency of ECG changes in patients with positive high-sensitive troponins (hs-cTn) presenting with NSTEMI.
Methodology: This Cross sectional study included 282 patients with positive hs-cTn diagnosed with NSTEMI. Standard 12-lead ECG was performed for all the patients. The clinical profile and ECG changes such as ST elevation in aVR, T wave inversion, and ST depression were noted.
Results: Out of 282 patients, 68.1% (192) were male, mean age was 58.5 ± 10.6 years, 56.7% (160) were hypertensive, and 39.7% (112) were diabetic. The ECG was normal in 8.2% (23) while, 64.5% (182) had ST-depression, out of which 1.1% (2) had ST-depression of <1mm, 78% (142) had ST-depression of 1-2mm, and remaining 20.9% (38) had ST-depression of >2mm. T-wave inversions were observed in 45.7% (129). ST-elevation of ≥1 mm in lead aVR was noted in 19.1% (54) patients.
Conclusion: A considerable number of NSTEMI patients with positive hs-cTn showed no specific ECG changes. ST-depression followed by T wave inversion and ST-elevation in aVR were the most commonly observed ECG findings in these patients. Considering the prognostic implications and association of these changes with the severity of diseases, prompt decision-making regarding invasive management strategy could be helpful in improving the outcomes of these patients.
Inferoposterior ST-Elevation Myocardial Infarction in a Patient with Frank’s Sign: A Case Report
Authors: Henrina Joshua , Teressa Maria , Wiraatmadja Agustinus , Purnama Asep , Cahyadi Alius
Published: April 2023

Coronary artery disease (CAD) is one of the main global causes of death. Early diagnosis by physical examination may play important role to identify population at risk and reduce morbidity and mortality. Diagonal Ear Lobe Crease (DELC), also known as Frank’s sign, was observed to be associated with coronary artery disease. We report a case of patient who presented with inferoposterior STEMI and findings of bilateral DELC. A systematic literature search was conducted to identify the latest evidence and its implications for clinical practice.
Online Collaborative Activities during Covid-19: Students’ Perception
Authors: Farrah Mohammed , Itkaidek Manar , Dandis Ameera
Published: April 2023

This study investigates the advantages and disadvantages of online collaborative learning activities as perceived by the English Department students at Hebron University, Palestine. A 34-item questionnaire was used to collect this data. The participants of the study consisted of 61 students at Hebron University. The researchers tried to illustrate the advantages and disadvantages of online collaborative activities and tried to give solutions for the challenges students may face. The results indicate that the students in general express positive attitudes towards the online collaborative activities, as they develop several areas for them. The results also show that the students face several problems in this experience, although they support and try to suggest some solutions to them.
Problem-Based Learning for Teaching Biology in Adult Education
Authors: Macanchi Procel Narcisa de Jesus , Seni Pinoargote Oscar David
Published: April 2023

This paper presents field research where the concepts of biology associated with genetic terminology related to the frequency of alleles have been analyzed from the implementation of two types of teaching methodologies: the traditional methodology with masterclasses and the problem-based learning methodology, and both applied to a group of people with unfinished schooling aged between 20 and 60 years. Experimental and control groups were taken, and pretest and posttest tests were conducted to determine the activity's contribution. The main results show that both methodologies are significant for learning. However, problem-based learning yielded better results than the pretest.
Calidad del sueño en estudiantes de ingeniería
Authors: Martinez Cristhian , Chacon Ana , Marquez Victor
Published: April 2023

En este trabajo se determinaron los factores que influyen en la calidad de sueño de los estudiantes de ingeniería, mediante un estudio descriptivo y trasversal. Se empleó una muestra aleatoria de 930 estudiantes de ingeniería eléctrica (124), mecánica (184), civil (281), industrial (164) y química (177). Se utilizó el cuestionario auto aplicable de Índice de Calidad de Sueño de Pittsburg que valora siete componentes hipotéticos, añadiendo al análisis algunas variables socioeconómicas. Se observó que un número importante de estudiantes duermen menos de 8 horas, además se pudo confirmar que la calidad del sueño afecta el desempeño académico ocasionando necesidades médicas, también se pudo constatar que las situaciones socioeconómicas, la carrera, el sexo, la edad y el lugar de procedencia son factores determinantes en la calidad de sueño.
AN UPDATED REVIEW ON HYPERTENSION
Authors: K Sowmyashree , S Vinutha , G Venkatesh K , K Prajwal Kumar Y , R Bharathi D , K Chandan
Published: April 2023

A common, aging-related chronic condition called hypertension frequently results in kidney and heart problems that are quite serious. A number of additional cardiovascular risk variables are frequently reported together with blood pressure. Automated blood pressure testing methods are becoming more and more common in the diagnosis of hypertension. The main or secondary kidney's failure to drain salt at a normal blood pressure is a prerequisite for the pathophysiology of essential hypertension.  Many people with hypertension are unaware of their disease, and among those who have been identified, therapy is typically insufficient. Population-level actions are necessary to stop the onset of hypertension as well as to enhance community hypertension awareness, care, and management. In this review we focus on the epidemiology, risk factors, and diagnosis, screening and preventive measures of hypertension.
Spline Model in The Case of Cervical Cancer Patient Resilience
Authors: Hidayat Rahmat , Ilyas Muhammad , Yuliani Yuliani
Published: April 2023

Cervical cancer ranks highest in developing countries, and ranks 10th in developed countries as a cause of death for women. In Indonesia, cervical cancer ranks second out of the 10 most common cancers based on Anatomical Pathology data in 2010 with an incidence rate of 20 %. The number of new women with cervical cancer ranges from 90 - 100 cases per 100,000 population and every year there are 40 thousand cases of cervical cancer. Cervical cancer is a gynecological disease that has a high level of malignancy and is caused by the Human Papilloma Virus (HPV). One method that can be used in the analysis of human survival is survival analysis using the Cox proportional hazard model. This research will use the development of the Cox model using the Spline function as its basis. Based on the results obtained, the developed model can model the data well and give a low MSE. Based on the developed model, it is found that the variables that influence the survival rate of cervical cancer patients are age, stage, type of PRC transfusion treatment and comorbidities.
HIGHLIGHTS

Due to in silico study such as molecular docking, molecular dynamic simulation is an important computational method for drug design. It can be used to predict the binding orientation of small molecule drug candidates to their protein targets. In addition, docking is also can be applied to predict small molecule affinity and activity. Thus, molecular docking has an important role in drug discovery and rational design
The ligand interaction with the receptor was more stable due to the decreased binding free energy value
The lowest binding free energy and lowest RMSD value of this molecule, which may presumably cause compound 3 to has better binding affinity compare to other compounds

GRAPHICAL ABSTRACT
Multiple Introduction and High Genetic Diversity: Drivers for Successful Establishment of Invasive Peacock Bass (Cichla spp.) in Peninsular Malaysia
Authors: Khaleel Aliyu Garba , Mohd Nasir Muhammad Syafiq Aiman , Mohd Dali Mohamad Zulkarnain , Madiran Norainsyafikah , Md Sheriff Shahreza , Seong Wei Lee , Hou Chew Ha , Ismail Norshida , Kamarudin Ahmad Syazni
Published: April 2023

The introduction of invasive Cichla spp. was followed by the several reports regarding the decline of local freshwater native species in Malaysia. The purpose of this research was to generate information concerning the introduction history of Cichla spp. in Malaysia. Studies on genetic diversity and structure provides the essential baseline data for monitoring and conservation of invasive species. This will help to clearly understand the propagule pressure and genetic distribution of Cichla spp. in the invaded freshwaters of Malaysia. A total of 61 samples of Cichla spp. were collected from 9 sampling location in Malaysia for mitochondrial DNA (control region) analysis. Overall samples showed high genetic diversity (Hd, 0.6700; π, 0.0254) and yielded 9 haplotypes resulted from different Cichla spp. present. The maximum likelihood tree with strong bootstrap support revealed that Cichla spp. forms 3 clusters, and confirmed to be C. monocoulus, C. occelaris and C. temensis. Except for Malacca populations, other populations were largely dominated by either C. monocoulus or C. occelaris. The current study suggesting that more than one introduction event of invasive Cichla spp. occurred in Malaysia.
HIGHLIGHTS

One of the common problem in the conservation effort for Malaysia’s freshwater aquatic ecosystem is failure to understand the introduction events of invasive species (Cichla)
Mitochondrial DNA analysis (control region) conducted in order to find the genetic diversity and genetic structure of invasive Cichla across freshwater habitats in Malaysia
High genetic diversity was observed, suggesting multiple introduction occurance of invasive Cichla in the country

GRAPHICAL ABSTRACT
The Rise of Secure IoT: How Blockchain is Enhancing IoT Security
Authors: T. Aditya Sai Srinivas  , A. David Donald  , I. Dwaraka Srihith  , D. Anjali  , A. Chandana
Published: April 2023

The convergence of the Internet of Things (IoT) and blockchain technology is revolutionizing the field of security. IoT devices are becoming increasingly prevalent in our daily lives, from smart homes to wearable technology, but they also pose a significant risk to cybersecurity. Blockchain technology offers a decentralized, tamper-proof network that can enhance the security of IoT devices. By creating secure identities, communication channels, and transactions, blockchain can protect IoT devices from potential cyber-attacks. This paper explores the advantages of using blockchain to enhance IoT security and highlights the potential of this technology to create a safer and more secure IoT ecosystem
Changing Scenario of Information Needs of Library Users with Special Reference to Women B.Ed Institutions in Jhunjhunu City
Authors: Nand Kishor  , Vaishali U. Bhakt (Chaudhari)
Published: April 2023

Women B.Ed. Institution in Jhunjhunu city in Rajasthan state library being considered as knowledge hub caters to the information needs of diverse categories of users like library users, research scholars, scientists, teachers, etc. by providing access to wide variety of learning resources. Apart from print resources Women B.Ed. Institution in Jhunjhunu city in Rajasthan state libraries are increasingly adding electronic resources like E-Books, E-Journals, E-Theses, databases, E-Standards, Institutional repositories, consortia, online public access catalogue and other networked resources to their collections which have been widely used nowadays as primarily for teaching, learning as well as research activities. Since the Library users are not involved in any kind of research work thus presumed to make use of most resources of books/notes/ e-books to fulfill their academic need The present review study is being conducted to ascertain the kind of information resources mostly used by the Library users and further to know their changing scenario level about resources & services of the library. It is basically a systematic review of studies conducted in the past to know their changing scenario level; information needs behavior and attitude towards different resources used in achieving the academic goals
Students’ Critical Thinking Skills Perform in Debate Activities
Authors: Naqia Dzakiyatun , As'ari As'ari , Suaidi Afif
Published: April 2023

This study aims to explore student’s critical thinking skills by finding out students' ability to develop arguments, supporting details, and the analysis to the problems and its solution. This study used a qualitative approach with a case study method through observation and interviews as data collection techniques. This study involves 6 members of English Club at SMAN 2 Kota Serang as participants. The results of this study showed students' abilities in developing arguments and supporting details such as: (1) Ability to research data, (2) ability to develop arguments, and (3) ability to explore references from various sources. in addition, the results of the analysis showed that students are able to identify problems and determine solutions. The points are as follows: (1) Comprehending the issue and (2) finding the best solution. Based on the results obtained, it can be concluded that the results of this study are able to answer the research questions.
A Utilização da Metodologia Ágil em Projetos do Segmento Industrial Automotivo
Authors: Catto Sergio Luiz , Antonio Maccari Emerson
Published: April 2023

Este estudo tem como objetivo evidenciar como a utilização da metodologia Ágil se desdobram no âmbito da gestão de projetos no segmento industrial automotivo na literatura científica. Este trabalho é uma Revisão Sistemática de Literatura, onde procedimentos foram aplicados na seleção de artigos das bases de dados Scopus e Web of Science, para a identificação e interpretação das principais publicações acerca do tema na literatura científica buscando compreender sua relevância e sua evolução. Os achados desta pesquisa contribuirão para o entendimento de como a utilização das metodologias ágeis pode contribuir para maximizar o sucesso nas tratativas praticadas nos projetos do segmento industrial automotivo. E devido às particulares características das metodologias ágeis, focar na eficiência da gestão e foco nos resultados. Esse trabalho contribui para a melhoria no entendimento dos benefícios da aplicação das metodologias ágeis na gestão de projetos no segmento industrial automotivo. Esta pesquisa aborda dois temas principais, atuais e bastante abrangentes – metodologias ágeis e gestão de projetos - envolvendo diversas disciplinas complementares encontradas nas obras coletadas (Automotive Industry; Impact; Implementation; Management;  Model; Performance; Process Engineering; Process Monitoring; Six Sigma; Six Sigma methodology; Work Simplification), que dão embasamento para a identificação de como estes temas se relacionam à presença e utilização das metodologias ágeis no gerenciamento de projetos no segmento industrial automotivo.
Análise da Gestão Secretarial na Gestão Documental: Um Estudo de Caso no Arquivo Geral da Universidade Federal de Pernambuco (UFPE)
Authors: Ferreira de Lucena Israel , Souza Tiago Morais de , Silva Rozângela Bezerra de Almeida , Moura Maria do Céu de Sena
Published: April 2023

A Gestão Secretarial relaciona-se com várias áreas do conhecimento, para tal, a Arquivologia está entrelaçada ao Secretariado Executivo pelo fato de que para as organizações, a informação representa seu maior ativo. O objetivo geral desta pesquisa consistiu em analisar a atuação da Gestão Secretarial na Gestão Documental do arquivo geral da Universidade Federal de Pernambuco (UFPE). Para tanto, os objetivos específicos consistiram em mapear as atividades da Gestão Documental; identificar as atividades realizadas que estão no âmbito da Gestão Secretarial; mapear a formação dos gestores e checar a percepção e entendimento do Gestor Documental com relação à Gestão Secretarial. A metodologia constou de um estudo de caso, pesquisa de campo de caráter exploratória através da coleta dos dados de forma direta, por meio da aplicação de questionários fechados e observação assistemática em grupo, em que os dados coletados foram submetidos às análises qualitativas. O resultado da pesquisa constatou que cerca de 78% dos servidores não dominam ou entendem pouco das técnicas secretariais, logo, este resultado se justifica pela inexistência de profissionais na equipe com a formação em Secretariado Executivo. Por fim através de uma intersecção, foi constato relação indiretas e diretas entre Arquivologia e Secretariado, por meio de convergências entre as práticas de ambas as áreas, sendo a Gestão Documental o elo entre elas.
A Influência da Formação Empreendedora na Carreira dos Egressos do Curso de Secretariado Executivo Trilíngue da Unioeste
Authors: Abich Jaqueline , Schmidt Carla , Daga Cielo Ivanete , Sanches-Canevesi Fernanda Cristina
Published: April 2023

Manter-se atualizado e investir em novos nichos de atuação são fatores preponderantes para todos os profissionais, a exemplo dos que atuam na área de Secretariado Executivo. Assim, o curso de Secretariado Executivo Trilíngue da Unioeste (SET) oferta a disciplina de Empreendedorismo em sua grade curricular, com o intuito de desenvolver e ampliar o leque de atuação dos profissionais. Neste contexto, este estudo busca, como objetivo central, investigar a inserção dos egressos do Curso de Secretariado Executivo Trilíngue da Unioeste, formados no período de 2017 a 2019 (59 egressos) no campo do empreendedorismo. Para tanto, aplicou-se um questionário a estes egressos e constatou-se que 20,33% deles constituíram seu próprio negócio. Além disso, os resultados ainda apontaram que a disciplina de Empreendedorismo contribuiu com o desenvolvimento das habilidades empreendedoras dos egressos, com destaque para a criatividade.  Em relação ao motivo que levou os egressos a abrirem os empreendimentos, a maioria afirmou buscar satisfação pessoal e ter maior autonomia.
Interchromophoric Twist: Gateway to Long-Lived Excitons
Authors: Jadhav Sohan D. , Hariharan Mahesh , Maret Philip Daniel
Published: April 2023

Structure-property-function relationships play a key role in governing physical properties in molecules and materials in the broader sense. Particularly in organic light-harvesting materials, the sensitivity is magnified as the vibronic and electronic energy landscapes are highly sensitive to the type and extent of quantum chemical communication between molecules. In this article, we select a particular geometric feature- the interchromophoric twist and discuss its implication on several fundamental photophysical properties in connection with our lab’s research interests. We highlight two important processes, singlet fission (SF) and symmetry- breaking charge separation (SB-CS). We narrate how the interchromophoric rotation angle can be a crucial tool in achieving an appropriate electronic coupling in each of the cases and help us utilize these processes to achieve long- lived excitons (triplets and unbound electron-hole pairs) for the design and development of efficient artificial solar energy systems.
The world of exotic crystals: Raman spectro-microscopy for probing local structure
Authors: Reddy C Malla , Ghosh Ishita , Kumar Rajesh , Tanwar Manushree
Published: April 2023

In this article, we review briefly the recent progress on mechanically responsive molecular crystals which defy the common perception that “crystals are rigid”. Crystals which respond to different external stimuli are emerging fast and may find applications in miniature technologies, sensors, flexible devices, and soft-robotics. Here, we present some early examples of molecular crystals from our group, along with other examples of our choice, to emphasize on the use of Raman spectromicroscopy technique for characterizing crystals, polymorphic forms and strained crystals in the context of structure- property correlation and crystal engineering.
Evolution of Chemistry for Precision Engineering of Proteins
Authors: V. Ragendu , Kumar Mohan , Molla Rajib , Thakur Kalyani , Chauhan Preeti , Rai Vishal
Published: April 2023

A chemical toolbox for protein bioconjugation drives the innovation at the biology-medicine interface. It provides an alternative to thebiochemical approaches while enabling access to a much more significant proteome segment. However, “precision” was often elusive from the bioconjugation methods till recently. The increasing knowledge of core principles for bond formation and dissociation with proteins has led to multiple breakthroughs in recent years. It also unraveled protein-driven reactivity and selectivity attributes unknown to small molecules′ chemical reaction repositories. This research field promises to address the growing demands in protein-based diagnostics and therapeutics.
Chemical Approaches to Tackle the Silent Pandemic of Antibiotic Resistance
Authors: Saini Snehlata , Shanbhag Chitra , Saraogi Ishu
Published: April 2023

The rapid rise of antibiotic resistance among infectious pathogens is a matter of grave concern. This development of resistance is an evolutionary process, which is intensified due to prolonged and excessive exposure to antibiotics, which will ultimately force us to a situation where well-established lines of treatment will cease to be effective against routine infections. Thus, it is imperative to develop novel strategies to tackle this silent pandemic of antibiotic resistance. Here we briefly summarize the far-reaching implications of antibiotic resistance globally and highlight some key mechanisms by which resistance arises. We also discuss possible approaches to address this problem, including the identification and validation of novel antibacterial pathways that can circumvent existing resistance mechanisms to effectively curb this global threat.
The Style of Internal Rhythm in The Poetry of Sarsari
Authors: Ibrahim Ghufran Khaled , Mohamed Latif Mahmoud
Published: April 2023

This study, tagged with (the style of the internal rhythm of Sarsari) sought to study the internal rhythm and enter into the poetry of Sarsari through a stylistic study, and to analyze all linguistic phenomena found in poetic texts by relying on the stylistic principles represented in phonetic stylistic structures, the researcher used the descriptive analytical approach In order to determine the language of the poet, his style, his poetic experience, and his artistic formations, as well as access to the significance of the texts, and the extent of the poet's ability to influence the recipient. These vocal formations were exemplified in the study of Al-Sarari’s rhythms through models of his poetry, and the elements of internal rhythm in the poet’s poetic discourse varied between (vocal or verbal repetition) and other rhythmic units such as (anagrams, parallelism, and letter distribution), which helped this On highlighting the aesthetics of the text and its meanings, the use of these intonations and linguistic units revealed the poet’s ability to express his feelings of pent-up obsessions and feelings, and This results from the good choice of the constructor for its phrases and words and the quality of its arrangement. The study of the internal rhythm was reflected in the psyche of the recipient, and this is the poet's deep vision that came through his poetry in its significance, inspiration, and beauty.
Conceptual Metaphor of Life in Emily Dickinson’s “My Life Had Stood- A Loaded Gun”
Authors: Shtewi Aiyad Ziyad , Hussein Juma’a Qadir
Published: April 2023

Conceptual metaphor is the structures that linguistically work to denotes metaphors. To the researcher's best knowledge, conceptual metaphor has been tackled from different perspectives; Still few studies have dealt with conceptual metaphor in the poetry of Emily Dickinson. The study deals with the types of conceptual metaphor of life in Emily Dickinson's My life had stood- a loaded gun. Therefore, this study aims at analyzing the types of conceptual metaphors of life in the target poem. To this end, the poem was purposefully and analyzed based on Lackoff and Johnson's (2003) model of conceptual metaphor theory. The findings revealed that there were 2 structural metaphors and 4 ontological metaphors.
Legal Protection for Works in The Digital Environment in International Agreements and Legal Legislation (Comparative Study)
Authors: Mohammed Fatima Jassim
Published: April 2023

The developments that the world witnessed and the existence of the technological revolution led to cyberspace being a stage for the dissemination of human intellectual creativity and the importance of this creativity and its role in the world led everyone to seek to protect it from any aggression that might be inflicted on it to ensure its continuity by creating a sense of security for its owners and based on that I proceeded Countries have to conclude international agreements and enact internal legislation that protects this type of digital creativity in all its forms from any form of attacks that may be exposed to it in the digital environment. This important and sensitive issue requires the development of national legislation and international agreements in a clearer and more detailed manner because many of these digital works are subject to violation and theft. to pursue violators.
O DESENVOLVIMENTO DO PROCESSO DE ENSINO- APRENDIZAGEM DO ALUNO COM NECESSIDADES EDUCACIONAIS ESPECIAIS
Authors: Silva Eva Aparecida Gomes da
Published: April 2023

O presente estudo tem como objetivo a análise do desenvolvimento do aluno com necessidades educacionais especiais no ensino regular. A metodologia aplicada foram as pesquisas bibliográficas, desenvolvendo a partir destas observações quanto à necessidade da criação de novos métodos e modelos de ensino para alunos da educação especial, em especial a alunos surdos. Este artigo demonstrará que o conhecimento do aluno e o auxílio de jogos e brincadeiras são eficientes para o processo de ensino-aprendizagem. Com a finalização deste artigo, pretende-se gerar uma maior confiança quanto as atividades lúdicas no processo de ensino-aprendizagem da educação infantil.
أخلاقيات (كف الأذى وحفظ اللسان وإفشاء السلام والإنفاق) في الأحاديث النبوية كتاب (الإيمان) من صحيح البخاري أنموذجاً (دراسة تحليلية)
Authors:   قسم الدراسات الإسلامية/ كلية العلوم الإسلامية/ جامعة السليمانية, طاهر إسماعيل ماهر , علي محمد إبراهيم ,   قسم الدراسات الإسلامية/ كلية العلوم الإسلامية/ جامعة السليمان
Published: April 2023

إنّ (للقيم الاجتماعية) أهمية كبرى في حياة الأمم والشعوب كونها الإطار المرجعي الذي يحكم علاقات أفراد المجتمع بعضهم ببعض وينظم شؤون حياتهم، فهي التي تحدد خيرية الفعل الذي يقوم به الإنسان من عدمه. ولقد أخبر نبيّ الإسلام (صلى الله عليه وسلّم) عن جملة من (القيم الاجتماعية) مثل: إفشاء السلام وإطعام الطعام والانصاف في التعامل مع الآخرين وبيان ما يجب أن يكون عليه المسلم تجاه أخيه المسلم من سلامة الصدر وكف الأذى عنه باللسان وباليد الى غير ذلك من أخلاق وسلوكيات لها ارتباط مباشر ووثيق بـ(القيم الاجتماعية).
قاعدة (الاجتهاد لا يُنقض بمثله) تأصيل وتطبيق
Authors:   جامعة الموصل / كلية العلوم الإسلامية / قسم الشريعة, طارق خضر سمية
Published: April 2023

تعد هذه القاعدة من القواعد المشتركة بين علمي أصول الفقه والقواعد الفقهية، فهي -في الأصل- قاعدة أصولية؛ لأنها تتعلق بأحد مباحث علم اصول الفقه وهو الاجتهاد، ويمكن ان تدرج ضمن القواعد الفقهية؛ لأن جزئيات موضوعها هو فعل المكلف أي القاضي، إذ يبحث الفقهاء في كتاب القضاء حكم نقض اجتهاده أيجوز أم لا؟ ولهذا عنونها ابن السبكي في كتابه الاشباه والنظائر بقوله: "فيما ينقض فيه قضاء القاضي وما لا ينقض". وتأتي أهمية هذه القاعدة من حاجة كل من القاضي والمفتي والمقلد اليها، فالقاضي يحتاج اليها لمعرفة الأمور التي يُنقض بها الحكم المبني على الاجتهاد، والمفتي يحتاج اليها لمعرفة الحالات التي يُنقض بها العمل باجتهاده الأول، والمقلد يحتاج اليها لمعرفة حكم بقائه على الاجتهاد الأول، هل يمكن البقاء عليه أو الانتقال إلى اجتهاد ثان، وقد عرضت لهذه المسائل كلها بين طيات البحث.
القدرة الإنسانية عند المتكلمين وعند الفقهاء والأصوليين دراسة مقارنة
Authors:   كلية الإمام الكاظم, مزعل لفتة جاسم
Published: April 2023

يُعد مصطلَح القدرة من المصطلَحات المشتركة، إذ استعمله علماء الكلام؛ لتعلقه بواحدة من أمات المسائل الكلامية؛ وهي مسألة القضاء والقدر، التي أُثيرت عند المسلمين منذ فجر الاسلام، ووقع البحث فيها بين علماء الكلام، وتعددت الآراء في أنّ الانسان قادر على الفعل والترك، أو أنّه مجبر على أحدهما؛ وليس له القدرة على الاختيار. واستعمل الفقهاء هذا المصطلَح أيضاً، إذ إنّهم ذكروا شروطاً عامة للتكليف الإلهي، فما لم تتوفر تلك الشروط لا يتوجه التكليف للإنسان، ومن هذه الشروط العقل والبلوغ وغيرهما مما هو مذكور في الكتب الفقهية. ومن الشروط العامة للتكليف قدرة المكلف على الاتيان بما كُلِّف به. ولعله لا يوجد باب من الأبواب الفقهية، لا يوجد فيه ذكر لهذا الشرط: لأصل الحكم الشرعي، أو لأحد أجزائه، أو شرائطه. وقد استُعمل المصطلَح نفسه في تلك العلوم من دون تمييز واضح للمعنى الذي يكشف عنه في كلٍ منها؛ فكان من الضروري تحديد معناه تحديداً دقيقاً في كلٍ من تلك العلوم؛ لاجتناب ما قد يفضي إليه ذلك من الخلط والاشتباه. وتعني القدرة عند المتكلمين حرية الاختيار بين الفعل والترك ويقابلها الجبر، وهذه القدرة –على القول بها- ممنوحة من الله تعالى حين خلقه للإنسان، ولا تتحكم بها الأسباب الطبيعية. في حين تعني القدرة عند الفقهاء سلامة الأعضاء والجوارح وسائر الأسباب التي تمكِّن المكلف من أداء التكليف، ويقابلها العجز. وهذه القدرة تتحكم بها الأسباب الطبيعية، كانعدام الصحة، أو انعدام المال، أو عدم تخلية السرب، ونحو ذلك ممّا يحول بين المكلف وبين أدائه للتكليف. وقد استند الفقهاء في اثبات هذا الشرط العام الى قاعدة مهمة بُحثت في علم أصول الفقه، سُمِّيت بأسماء متعددة: نحو قاعدة التكليف بما لا يُطاق، أو التكليف بالمحال، أو التكليف بالممتنع، أو التكليف بغير المقدور، إذ قام الأصوليون هناك بإثبات أنّ التكليف من دون قدرة غير ممكن، واستدلوا بأدلة من الكتاب والسُّنة والعقل، لإثبات شرطية القدرة في التكليف.
Presencia digital en las MiPyMEs con establecimiento físico en México
Authors: Valdez-Palazuelos Omar , Ovalles-Toledo Luiz Vicente , Bueno-Camacho Federico , Meriño Córdoba Víctor Hugo
Published: April 2023

La globalización ha obligado a las Micros, Pequeñas y Medianas Empresas (MiPyMEs) a buscar alternativas que permitan posicionarse ante un mercado cada vez más competitivo, en ese sentido, este trabajo tiene como objetivo, analizar los elementos que constituyen la presencia digital y su aprovechamiento actual en las MiPyMEs con establecimiento físico en México; Para ello, se realizó una investigación descriptiva de tipo cuantitativo, donde a través de una muestra a conveniencia se eligieron de manera aleatoria 426 empresas de estas características, de la zona centro de la ciudad de Culiacán, Sinaloa, encontrándose que existe un elevado porcentaje de estas empresas que no cuentan con un perfil digital de negocio en la plataforma de Google mi Negocio, así mismo analizando otros elementos clave de la presencia digital en otros medios tales como redes sociales, sitio web y uso de mensajería instantánea. Se destaca que existe una gran oportunidad para estas empresas de aprovechar en mayor medida las herramientas de apoyo para la mejora de su presencia digital que actualmente están a su alcance.
Gerencia educativa desde la metodología integrada input-output del modelo dinámico
Authors: Carranza Hernández Karina Milena , Salazar Leyva Máryury , Hinojosa Hernández Marcos de Jesús
Published: April 2023

El propósito es analizar la gerencia en las organizaciones educativas a través de la metodología integrada input-output del modelo dinámico con tecnologías emergentes, en las Instituciones “Camilo Torres Restrepo, San José y San Isidro”, municipio Curumaní (Cesar-Colombia). La investigación fue de tipo analítica; apoyada en el enfoque cualitativo macroetnográfico. De acuerdo con el encuadre epistemológico la investigación se considera fenomenológica. La técnica utilizada fue la entrevista a profundidad, aplicando el guión de entrevista dirigido a nueve (9) docentes informantes clave de las instituciones mencionadas. En la educación básica secundaria, la metodología integrada input-output del modelo dinámico utilizando las tecnologías emergentes, no constituye una prioridad del docente para dar respuesta al aprendizaje mediado por la virtualidad durante el Covid-19. Finalmente, es necesario que los gerentes de aula apliquen de manera efectiva los elementos teórico-prácticos relacionados con la metodología integrada input-output, para orientar asertivamente al estudiante en su proceso de aprendizaje.
Analysis Of Factors Influencing The Number Of Poor Population Provincial Central Kalimantan
Authors: Manurung Mariduk , Jaya Misel
Published: April 2023

ABSTRACT

The purpose of this study is to analyze the factors that affect the number of poor people of Central Kalimantan Province. The data used in this study is secondary data obtained from the Central Bureau of Statistics (BPS) of Central Kalimantan Province. The research method used is Ordinary Least Square Method (OLS), multiple linear regression method and to manage the data using SPSS version 17 software.

The results of this study indicate that: a) Economic growth has a positive and insignificant effect on the number of poor people of Central Kalimantan Province. b) Per capita income has a negative and significant effect on the number of poor people of Central Kalimantan Province c) Inflation has a positive and significant impact on the number of Poor People of Central Kalimantan Province. d) Open Unemployment has a positive and insignificant effect on the Number of Poor People of Central Kalimantan Province. as well as the variables of these studies together significantly affect the Poor Population of Central Kalimantan Province.
Analysis Of Employment In The Hospitality Sector And Other Accomodation In The City Of Palangka Raya
Authors: Simanjuntak Royen , Harati Rima
Published: April 2023

ABSTRACT

The purpose of this study is to determine the role of the hospitality sector and other accommodation on the amount of labor absorbed in the sector. This research uses quantitative method with cross sectional approach. The results showed that: a) Where the number of rooms, room rental prices and number of visits have a positive and significant impact on employment. b) The value of coefficient number of rooms amounted to 0.443 means that if there is an increase of 1% of the number of rooms then the absorption of labor by 0.443%. c) The coefficient value for the room rental price of 0,507 means that if the room rental price increases by 1% causes the increase in the amount of labor by 0.507%. d) Value of visitor number coefficient of 0.279 means if the number of visitors increased by 1% then the employment of 0.279%. The results showed X1, X2, X3 simultaneously have a significant effect on employment in the hospitality sector and other accommodation in Palangkaraya City and T-test results indicate that star hotels and non-star hotels have an influence on visitors to choose hotels.
Analysis of Determinants of Economic Growth in Central Kalimantan Province
Authors: Asrawi Faisal , Embang Andrie Elia , Bakar Miar
Published: April 2023

ABSTRACT

This study aims to determine and analyze the effect of capital expenditure on economic growth in Central Kalimantan Province, to find out and analyze the effect of investment in the form of domestic investment (PMDN) on economic growth in Central Kalimantan Province, to find out and analyze the effect of investment in foreign investment (PMA) on economic growth in Central Kalimantan Province, to find out and analyze the influence of exports on economic growth in Central Kalimantan Province. The research method used is descriptive quantitative with time series secondary data 1995-2014. Then the data will be analyzed using multiple linear analysis. The results showed that capital expenditure has a positive and significant effect on economic growth in Central Kalimantan Province, domestic investment (PMDN) has a positive and significant effect on economic growth in Central Kalimantan Province, foreign investment (PMA) has a negative and not significant effect on growth economy in Central Kalimantan Province, exports have a negative and not significant effect on economic growth in Central Kalimantan Province.
Analysis of Prospects of Refilling Mineral Water Business in The City Palangka Raya
Authors: Ompusunggu Febri Humisar , Embang Andrie Elia , Sabirin Sabirin
Published: April 2023

This study aims to determine and analyze: 1) The factors that influence consumer demand forrefill drinking water in Palangka Raya City; 2) The effect of per capita income, average price andpopulation on the demand for water in Palangka Raya City; and 3) Growing demand for refilldrinking water in the City of Palangka Raya. The research methods in this thesis are descriptivestatistical analysis, multiple linear regression, and linear trend analysis. The independentvariables in this study are family income, water prices, and the number of family members whilethe dependent variable is the business prospects of mineral water refill. The population in thisstudy is the number of households that consume water from mineral water refill depots in theCity of Palangka Raya. The sample in this study were 40 respondents in the City of PalangkaRaya based on the theory of sampling and sample size by Uma Sekaran in multivariate research.The type of data used is primary data and secondary data. The results of this study indicate that:1) Factors affecting the demand for mineral water based on primary data are consumer income,water prices, and the number of family members; 2) Simultaneously (simultaneously) there is a significant relationship between consumer income, the average price of water, and the number offamily members to the demand for mineral water in Palangka Raya City; and 3) There is agrowth in demand for mineral water based on per capita income, the average price of brandedwater, and the number of residents in the City of Palangka Raya
Influence of Accountability And Transparency on The Management of The Apbesa of Tumbang Bunut Village, Rungan District, Gunung Mas Regency
Authors: NINGSIH SELVIANI , RAHMIATI RAHMIATI , DIARSYAD M.ICHSAN
Published: April 2023

The porpose of this study is to determine the readiness of village government in realizing accountability and transparency in the management of APBDesa By quantitative method there hypotheses proposed in this study. The subjects of this research are 4 principal areas of village, village government of Tumbang Bunut, The sampling technique in this research is done using the techningque of vorposive sampling the instrument of data collection in this research is questionnaire of questionnaire. The resuls of this study indclate that accountability is positively releated to the management of APBDesa, Transparency is also positively realited to the management of APBDesa, and accountability, and transparency together have a positive relationship to APBDesa Mangement
Analysis Of Regional Acceptance Potentials From The Tourism Sector In West Kotawaringin, East Kotawaringin, And Palangka Raya City
Authors: DAHLIA DAHLIA , TIAWON HARIN
Published: April 2023

This study aims to analyze and determine the potential revenue of the tourism sector on Regional Original Income in three regions, namely West Kotawaringin Regency, East Kotawaringin Regency, and Palangka Raya City. The data used is qualitative data and is also supported by quantitative data, the method used in this research is descriptive qualitative. Data analysis uses the contribution of tourism income to Regional Original Income, namely using an analysis of the contribution of PAD based on the classification of contribution criteria. The results of this study indicate that the different tourist characteristics between the three regencies/cities have their own tourist attractions. But the number of tourists visiting only come directly to the tourist attraction, so that previously the tourism industry was a source of income for the private sector and the region through restaurant taxes or hotel taxes, now the source of income from the tourism industry is less contributing to Regional Original Income