bluuebunny/crossref_metadata_2025 huggingface dataset:
TRENDS IN THE SOCIO-ECONOMIC BEHAVIOR OF BUSINESS ENTITIES IN THE POST-COVID ERA
Authors: Шинкарёва О.В. , Алексейчева Е.Ю. , Куломзина Е.Ю.
Published: July 2024

В исследовании описаны выявленные направления социально-экономической жизни России в постковидную эпоху, основанные на исследованиях российских ученых в этой области, данных ФНС и Росстата, опросах Всероссийского центра изучения общественного мнения. Отмечено, что исследования фиксируют ослабление социального комфорта, рост чувства социальной незащищенности граждан, уменьшение уровня индивидуальной социально-экономической автономии граждан на фоне роста экономической и социальной зависимости от государства, а также то, что пандемия COVID-19 может стать поводом глубоко переосмыслить методы управления, механизмы взаимодействия между государством, обществом, бизнесом. Показан риск, который может негативно повлиять на прогнозируемый восстановительный рост экономики страны в будущем, — снижение потребительского спроса в связи с ростом сберегательных настроений населения.

The study describes the identified directions of the socio-economic life of Russia in the post-covid era, based on research by Russian scientists in this area, data from the Federal Tax Service and Rosstat, surveys by the All-Russian Center for the Study of Public Opinion. It was noted that studies record a weakening of social comfort, an increase in the feeling of social insecurity of citizens, a decrease in the level of individual socioeconomic autonomy of citizens against the background of an increase in economic and social dependence on the state, as well as the fact that the COVID-19 pandemic can become an occasion to deeply rethink management methods, mechanisms of interaction between the state, society, business. The risk is shown that may negatively affect the projected recovery growth of the country’s economy in the future — a decrease in consumer demand due to the growth of savings sentiment of the population.
ORGANIZATION OF TAX PLANNING IN THE FINANCIAL SPHERE OF AN ECONOMIC ENTITY
Authors: Латышева А.Ю. , Костюков К.И.
Published: July 2024

В научной статье представлено рассмотрение вопросов налогового планирования как наиболее важного элемента финансовой политики экономического субъекта, способствующего повышению эффективности предпринимательской дея- тельности посредством минимизации и оптимизации налоговых платежей. Актуаль- ность данной темы определена стремлением налогоплательщиков снизить налоговые выплаты и столь же объяснимым стремлением государства воспрепятствовать этому. Налоговое планирование в Российской Федерации представляет собой постоянно развивающуюся сферу деятельности. В случаях выплат экономическим субъектом всех налоговых платежей по стан- дартной налоговой ставке является следствием ошибочного налогового менеджмента. Цель данного исследования заключается в построении оптимизированных этапов налогового планирования, обеспечивающих на своем выходе уменьшение налоговой нагрузки экономического субъекта. В работе мы представили различные инструменты налогового менеджмента и на их основе разработали этапы налогового планирования, которые могут быть внедрены в деятельность экономических субъектов с разной отраслевой спецификой. Этапы представляют собой четкий последовательный процесс.
STATISTICAL RESEARCH OF THE STATE OF THE REGIONAL INFRASTRUCTURE OF INFORMATIZATION AND COMMUNICATIONS OF THE POPULATION OF THE RUSSIAN FEDERATION
Authors: Платонова И.В.
Published: July 2024

В данной статье приведен сравнительный анализ распределения объемов инвестиций в субъекты РФ по виду деятельности в области информатиза- ции и связи в 2017 и 2020 годах, подтверждающий усугубляющуюся региональную дифференциацию. Определен набор основных показателей для исследования. Выяв- лены регионы с отличительными чертами в состоянии и развитии информационной и коммуникационной инфраструктуры населения РФ. Проведен корреляционный анализ и анализ дескриптивных статистик. С помощью неиерархического метода k-средних получена кластерная модель субъектов РФ, характеризующая уровень разви тия инфор матизации и коммуникаций населения РФ.
DEVELOPMENT OF MODELS OF ANTI-CRISIS MANAGEMENT OF SME ORGANIZATIONS IN MODERN CONDITIONS
Authors: Газгиреев А.Ш.
Published: July 2024

Данное исследование посвящено разработке моделей антикризис- ного управления малых и средних организаций в условиях современных вызовов. Тема развития моделей антикризисного управления организаций МСП в условиях современных вызовов является актуальной и важной в современном бизнес-мире. В настоящее время, когда мировое сообщество сталкивается с глобальными вызова- ми, такими как пандемия COVID-19, негативные экономические явления, изменения в мировой политике и технологические изменения, организации МСП становятся особенно уязви мыми и нуждаются в эффективных моделях антикризисного управ- ления. Развитие моделей антикризисного управления является ключевым фактором для обеспечения устойчивости и развития организаций МСП в период кризиса. В ста- тье анализируются основные проблемы, с которыми сталкиваются МСП в период кризиса, а также представлены модели антикризисного управления, которые способны обеспечить сохранение устойчивости и развития организаций МСП в сложный период кризиса.
ANALYSIS OF FOREIGN EXPERIENCE OF COMMUNICATION BETWEEN AUTHORITIES AND THE POPULATION IN THE FIELD OF URBAN TRANSPORT DEVELOPMENT
Authors: Темникова Ю.Ю.
Published: July 2024

Процесс коммуникации органов управления городским транспор- том и населения на сегодняшний день выступает одним из приоритетов развития управленческих моделей в системе транспортного обслуживания. Цель исследования заключается в проведении анализа зарубежного опыта коммуникации органов власти и населения в сфере развития городского транспорта и выявлении ключевых факторов успешности данного процесса. В статье определены понятие, структура и ключевые функции коммуникации органов власти и населения в сфере развития городского транспорта, сформулированы критерии эффективности систем коммуникации органов власти и населения в сфере развития городского транспорта. Представлены результаты анализа опыта коммуникации органов власти Сингапура, Пекина, Лондона, Парижа, Нью-Йорка и Токио с населением. На основании полученных данных определены ключевые факторы успешности систем коммуникации органов власти и населения в сфере развития городского транспорта.
The relevance of appeal to the heritage of K. D. Ushinsky in the process of professional training of lawyers
Authors: Румянцева О.О.
Published: July 2024

В статье приведены примеры закономерного обращения к наследию выдающегося отечественного педагога К. Д. Ушинского при подготовке специалистов юридической сферы. Базу наблюдений составляет деятельность кафед ры русского языка и культуры речи Российского государственного университета правосудия (РГУП). Целью работы является обобщение и трансляция практического опыта, накоплен- ного названной кафедрой благодаря использованию педагогических идей и художест- венно-публицистических текстов К. Д. Ушинского. Методология и методы. Изыскание опирается на труды К. Д. Ушинского, а также современных авторов и содержит системно-функциональный анализ педагогического опыта; применяются методы наблюдения, описания, синтеза. Основные результаты исследования. Автором представлен учебно-воспитатель- ный потенциал произведений К. Д. Ушинского при подготовке современных юристов. Научная новизна. Продемонстрированы возможности обращения к наследию К. Д. Ушинского в целях личностного и профессионального развития будущих юристов. В стенах РГУП это представляется особенно важным, потому что сам К. Д. Ушинский получил юридическое образование. Практическая значимость. Результаты исследования могут быть полезны для органи- зации учебно-воспитательного процесса в сфере среднего и высшего профессио нального образования, а также могут быть применены в деятельности специалистов, которые связа- ны с юриспруденцией и педагогикой. Апробацией результатов работы стало выступление автора с докладом на ХХVII Межрегиональных педагогических чтениях «К. Д. Ушин- ский и русское национальное образование. Исторические уроки, идеи и совре менность», которые проходили в Московском городском педагогическом университете в рамках реализации проекта «Мероприятия в честь 200-летия со дня рождения одного из основа- телей российской педагогики Константина Дмитриевича Ушинского».
A Generalized Theory of the Chemical Kinetics from Statistical Mechanics
Authors: Brandes Benedikt Axel
Published: July 2024

In this contribution, I derive the transition state theory through a probabilistic model embedded in statistical mechanics. This leads to a formulation equivalent to the Eyring equation proving that the transfer coefficient must always be one. This derivation proves that the transition between two systems that are themselves in thermal equilibrium, but separated by a bidirectional transition of any kind, can be described by the Eyring equation. The herein presented derivation does not only lead to the prediction of chemical kinetics, but also provides another proof of the second law of thermodynamics demonstrating intuitively how chemical kinetics, energy, and entropy are all fundamentally statistical phenomena.
A Lead(II) Substituted Triplet Carbene
Authors: Dankert Fabian , Messelberger Julian , Swain Abinash , Authesserre Ugo , Scheschkewitz David , Morgenstern Bernd , Munz Dominik
Published: July 2024

Reaction of the pincer-type ligand L3 supported complex [L3PbBr][BArF24] (1) with Li[(C(=N2)TMS)] furnishes [L3Pb(C(=N2)TMS)][BArF24] (2). Diazo-compound 2 eliminates dinitrogen upon irradiation affording formal plumba-alkyne 3, which persists in cold fluoroarene solutions. Variable temperature UV/Vis and NMR spectroscopies in combination with quantum-chemical calculations identify 3 as a metal-substituted triplet carbene. In-crystallo irradiation of [L3Pb(C(=N2)TMS)(tol)][BArF24] (2∙tol) provides a snapshot of intermolecular C–H bond insertion with toluene (4).
An in vitro one pot synthetic biology approach to emulating Golgi O-glycosylation divergence in MUC1 and tumor associated MUC1
Authors: Nashed Abdullateef , Naidoo Kevin
Published: July 2024

Peptide O-glycosylation is a non-template driven process dependent on an orchestrated collaboration of glycosyltransferases (GTs) in the ER and golgi apparatus. An in vitro modelling of this requires an understanding of GT specificities, kinetics and their spatial distribution along the ER-Golgi axis. This study explores the specificity and kinetics of O-GalNAc glyco-sylation on a designed tandem repeat of MUC1 (23mer), a protein significantly implicated in cancer progression. Using an in vitro one-pot synthetic biology approach, MUC1 glycopeptides were produced, and GT specificity for cancer-associated anti-gens Tn, T, and their sialylated forms were assessed. The impact of GT re-localization from the ER to Golgi on glycosyla-tion patterns was modelled and analyzed. The model suggests that presenting MUC1 to GALNTs in isolation from other GTs, namely C1GALT1 and ST6GALNAC1 significantly increases the extent of site occupancy by Tn a tumour epitope. This mimics the ER localization of GALNTs associated with cancer. In contrast when MUC1 is presented to GALNTs in combination with C1GALT1 there is a decline in observed occupancy. Our modelling shows this to be the result of a com-petition between the secondary glycosylation of the GalNac sites by C1GALT1 and the GALNTs’ lectins that need to bind to the GalNac sites to further proceed with the primary glycosylation of adjacent free sites. In the case of normal MUC1 C1GALT1 shows greater specificity to the under-occupied (GalNAc3-23mer) form of Tn. In the cancer case ST6GALNAC1 shows greater specificity to the fully occupied form (GalNAc5-23mer). These results suggest a mechanism of regulation of tumour associated MUC1 antigens independent of GTs expression level.
Will it blend? Exploring the viscoelastic characteristics of P3HT-polyborosiloxane blends towards flexible electronic materials
Authors: Gilhooly-Finn Peter A. , Westwood Megan M. , Schroeder Bob C.
Published: July 2024

Organic semiconducting polymers blended into elastomeric materials has shown to be a successful method for improving flexibility designed for wearable electronics. One such elastomer that has not been readily explored in combination with an organic semiconducting polymer is polyborosiloxane (PBS). PBS shows remarkable viscoelastomeric properties, due to the borate ester groups that crosslink the siloxane backbones, demonstrating a dynamic covalent crosslinking mechanism. The detailed study presented here showcases the properties of two different PBS elastomers and the effect of blending a well-known organic semiconducting polymer, poly(3-hexylthiophene) (P3HT). Compatibility studies find that one elastomer blends more favourably than the other due to differences in the crosslinking density leading to the formation of P3HT crystallites within the blend. The viscoelastic properties of the PBS:P3HT blends are studied through detailed rheological experiments and the relaxation processes are discussed.
Identification of Peptide-Based Hepatitis B Virus Capsid Inhibitors Based on the Viral Core Protein
Authors: Kawahara Kazutoshi , Fujimoto Junko , Takeo Sayuri , Sato Kohei , Nakashima Kenji , Mase Nobuyuki , Yokoyama Masaru , Suzuki Tetsuro , NARUMI Tetsuo
Published: July 2024

In this study, we have identified two novel peptides, 19Ac (comprising residues 91-105) and 20Ac (encompassing residues 96-110), from a systematically designed peptide library based on the Hepatitis B virus (HBV) core protein, that inhibit the assembly of HBV capsid. Peptide 20Ac exhibited about twofold the inhibitory potency of 19Ac and proved effective against both standard and morphothiadin (GLS4)-resistant HBV strains. Molecular dynamics simulations revealed that despite their overlapping sequence, 19Ac and 20Ac bonded to different regions of the core protein, thereby inhibiting capsid assembly through distinct mechanisms. These peptides could serve as valuable seed compounds for the further development of HBV capsid inhibitors, including GLS4-resistant strains.
Ab Initio Molecular Dynamics Study of Trivalent Rare Earth Rich Borate Glasses: Structural Insights and Formation Mechanisms
Authors: Ohkubo Takahiro , Sasaki Syunta , Masuno Atsunobu , Tsuchida Eiji
Published: July 2024

In this work, trivalent rare earth (RE)-rich borate glasses (30La2O3-70B2O3, 50La2O3-50B2O3, 60La2O3-40B2O3, and 50Y2O3-50B2O3) were modeled using ab initio molecular dynamics (AIMD) simulations through the melt-quenching route. It was found that the AIMD-derived structures reproduced the experimental structure factors and 11B solid-state nuclear magnetic resonance data. Isolated borate units (monomers, dimers, and trimers) terminated with non-bridging oxygen were found in the structures. Polymer units containing four or more boron atoms were identified with and without three-membered boron rings (Bring). Increasing the proportion of La2O3 in La2O3-B2O3 glasses resulted in an increased number of isolated units, indicating that La3+ acts as a network modifier, breaking the borate glass network. The formation of these units via the melt-quenching process was detected by labeling boron species at each AIMD step from $1500$ to 300 K. Representation with transition matrices clarified the specific reaction routes leading to the formation of isolated boron units in solid glass. A key finding is the stabilization of polymer units involving ring formation. The formation of isolated units is achieved through the reaction of polymers without rings. The RE coordination structure was thoroughly analyzed from the perspective of shape and symmetry. Reference structures derived from the solution of the Thomson problem were compared to the AIMD-derived coordination structures and crystalline LaBO3 and YBO3. The results highlight the specificity of the Y coordination structure with rings in YBO3, which is not observed in RE borate glasses. The analytical approaches and interpretations used in this study provide insights into the diverse coordination structures of glasses containing heavy elements other than REs.
COOPERATION OF NURSING STAFF AND THEIR SATISFACTION WITH WORK IN THE HOSPITAL OF A MEDICAL ORGANIZATION
Authors:   AL-FARABI KAZAKH NATIONAL UNIVERSITY, Demeubaeva Dinara , Kapanova Gulnara , Grjibovski Andrej , Dikanbaeva Saule , Zhappargaly Nurken , Tashenova Gulnara
Published: July 2024

A "team" in healthcare is traditionally referred to as an interdisciplinary team. Studying this particular professional group is important to understand how teamwork exists among those who provide most of the patient care. Communication skills contribute to the development of interpersonal relationships. Improving the quality of communication between participants in the healthcare system is a global priority and can contribute to better diagnosis and treatment. The purpose of the study: to study the relationship of interpersonal communication with the degree of job satisfaction of a nurse among nurses. Meterials and methods Design is an observational cross–sectional study using analytical statistics methods. Data collection was carried out using a survey (using the on-line Google Form server), in one of the State Clinical Hospitals in Almaty, in 2023. 281 nurses participated in the study. The questionnaire developed by us is an assessment of the strategy of behavior of nurses in the event of a conflict situation) It was carried out using Pearson's chi-square criterion and/or Fisher's exact test, with the calculation of relative risk (RR), as well as binary logistic regression. In addition to these basic methods, the following tests were used for analysis: single-sample binomial criterion and single-sample chi-square criterion. The null hypothesis was rejected in the case of p <0.05. Results and discussion In general, the proportion of nurses who were satisfied and dissatisfied with their work was 39.86% (n=112) and 60.14% (n= 169), respectively. The asymptotic significance of a single sample binomial criterion was p=0.001, which indicates the reliability of differences in proportions. Among the nurses dissatisfied with their work (n=169), the following prevailed: older sisters (χ2=40.645, p≤0.001), sisters with less work experience (χ2=90.941, p≤0.001) and sisters engaged in practical activities (χ2=83.568, p≤0.001). The results obtained indicate the presence of a statistically significant association of the level of satisfaction of nurses with work activities with such characteristics as "team cohesion" (RR=8,050, p≤0.001), "the level of trust in the team" (RR=3,470, p≤0.001), "friendly and business criticism in the team" (RR=3.393, p=0.004), "free expression of opinion in the team" (RR=12.285, p≤0.001), "the emotional attitude with which you usually come to work" (RR=4.442, p=0.003) and "the moral and psychological climate in the team" (RR=7.068, p≤0.001).
Fundamentación teórica sobre inteligencia emocional y su gestión a través del teatro en educación básica primaria
Authors: Pinto Lara Yasmin Liliana , Rodríguez Castro Diana Marcela , Sarmiento Sanabria Wendy Natalia
Published: July 2024

El presente estudio aborda la fundamentación teórica alrededor de la inteligencia emocional y su manejo a través de la educación teatral desde edades tempranas. Este texto contextualiza la importancia del conocimiento, el manejo y la gestión de las emociones. Asimismo, identifica la importancia de la educación en las emociones de los niños y niñas de edad primaria y su relación con el manejo apropiado de situaciones presentes en la cotidianidad. Además, se remite a las afirmaciones y teorías alrededor de la importancia de la educación en las artes escénicas, particularmente del teatro, en los entornos escolares, así como su relación con el manejo de las emociones. El estudio de estos temas pretende identificar las posibilidades que puede brindar la educación sobre la inteligencia emocional a través del teatro en niños en los años de educación básica primaria. La investigación encontró que existe una relación entre los fines de la enseñanza de la inteligencia emocional y del teatro que convergen en el reconocimiento y gestión de las emociones. Finalmente, se evidencia que el reconocimiento, el manejo y la práctica de las emociones son elementos fundamentales para el desarrollo integral de los niños en educación básica primaria y que a través del teatro se pueden generar espacios de apropiación, canalización y manejo de estas, fortaleciendo aspectos sociales del individuo.
Analisis Yuridis Perkembangan Tindak Pidana Pencucian Uang Saat Ini Sebagai Upaya Pencegahannya Di Indonesia
Authors: Saptono Saptono , Hadiyanto Alwan , Ciptono Ciptono
Published: July 2024

The aim of this study is to study efforts to prevent the criminal practice of money laundering in Indonesia. Research on the prevention of money laundering crime in Indonesia is critical and urgent, given the huge impact it has on the economy and national security. Money laundering not only undermines the integrity of the financial system, but is also often associated with other crimes such as corruption, drug trafficking, and terrorist financing, which can threaten social and political stability. The research has made an important contribution to strengthening the TPPU prevention system and raising awareness of the urgency of combating money laundering crimes in order to maintain economic stability and national security. This research uses normative research methods and uses secondary data. The prevention of TPPU in Indonesia is a very important and urgent matter. The impact of the TPPU not only undermines the integrity of the financial system, but is also potentially linked to other crimes such as corruption, drug trafficking, and the financing of terrorism, which can threaten the country's social and political stability. Effective prevention strategy but also synergy between the Government, the DPR, and PPATK. Prevention steps with the principles of Costumers Due Diligence Principle and the Know Your Customer system as one of the ways of TPPU prevention.  

 

Tujuan dari penelitian ini adalah untuk mengkaji upaya pencegahan praktik tindak pidana pencucian uang (TPPU) di Indonesia. Penelitian tentang pencegahan tindak pidana pencucian uang di Indonesia sangat penting dan mendesak, mengingat dampak besar yang ditimbulkannya terhadap ekonomi dan keamanan nasional. Pencucian uang tidak hanya mengganggu integritas sistem keuangan, tetapi juga sering terkait dengan kejahatan lain seperti korupsi, perdagangan narkotika, dan pembiayaan terorisme, yang dapat mengancam stabilitas sosial dan politik. Penelitian ini memberikan kontribusi penting dalam memperkuat sistem pencegahan TPPU dan meningkatkan kesadaran akan urgensi memerangi kejahatan pencucian uang guna menjaga stabilitas ekonomi dan keamanan nasional. Penelitian ini menggunakan metode penelitian normatif dan menggunakan data sekunder. Upaya pencegahan TPPU di Indonesia merupakan hal yang sangat penting dan mendesak. Dampak dari TPPU tidak hanya mengganggu integritas sistem keuangan, tetapi juga berpotensi terkait dengan kejahatan lain seperti korupsi, perdagangan narkotika, dan pembiayaan terorisme, yang dapat mengancam stabilitas sosial dan politik negara. strategi pencegahan yang efektif tetapi juga adanya sinergi antara  Pemerintah, DPR, dan PPATK.  Langkah pencegahan dengan prinsip Prinsip Costumers Due Diligence Principle dan sistem Know Your Customer sebagai salah satu cara pencegahan TPPU.  
The Effect of Tibetan Medicine 15-Flavor Gentian Flower Pills Combined with Budesonide on the Expression of Inflammatory Factors in Asthmatic Mice
Authors: Ge Liji , Li Jing , Yang Xudong , Li Xu , Zhai Xiaoting , Yang Kun , Zhang Hongyan , Ji Xu
Published: July 2024

Objective: To investigate the effects of the Tibetan medicine 15-flavor gentian flower pills combined with budesonide on the expression of inflammatory factors in asthmatic mice. Methods: 50 healthy female BALB/c mice of 6–8 weeks were selected and randomly divided into five groups, including the control group, the asthma group, the budesonide group, the 15-flavor gentian flower pill group, and the combination group. The budesonide group was fed with budesonide suspension, the 15-flavor gentian flower pill group was fed with 15-flavor gentian flower pill suspension, and the combined group was fed with budesonide suspension and 15-flavor gentian flower pill suspension. Asthma symptoms of mice in the five groups were recorded. Serum ovalbumin (OVA)-specific antibody levels, the proportion of eosinophils in bronchoalveolar lavage fluid (BALF), and the relative expression of inflammatory factors were compared among the five groups of mice. Results: Mice in the asthma group, budesonide group, 15-flavor gentian flower pill group, and combination group presented asthma symptoms. The OVA-specific antibody levels, the proportion of eosinophils, and expression of inflammatory factors (IL-4, IL-33, IL-5, and TNF-α) in the budesonide group, the 15-flavor gentian flower pill group, and the combined group were significantly better than those in the asthma group (P < 0.05); the OVA-specific antibody levels, the proportion of eosinophils, and expression of inflammatory factors (IL-4, IL-33, IL-5, and TNF-α) in the combined group were significantly lower than those in the budesonide group and the 15-flavor gentian flower pill group (P < 0.05). Conclusion: The Tibetan medicine 15-flavor gentian flower pills combined with budesonide can effectively inhibit the expression of inflammatory factors in asthmatic mice.
Global Trends and Insights in Actuarial Accounting for Insurance Companies: A Bibliometric Study
Authors: Ahmuda Mohamed Aghel , Yakhlf Mahmoud Abdualaziz Y
Published: July 2024

Purpose: This research examines the relationship between actuarial accounting and insurance; with particular reference to its emergence, current status, and major achievement. By employing research strategies of bibliometric, this study aims to establish findings in regard to trends, authors, organizations, countries and Intellectual cooperative systems influencing Actuarial Accounting in the Insurance market.
Design/Methodology/Approach: This research employs bibliometric analysis inclusive of the Scopus database to obtain actuarial accounting and insurance articles from the publication years between 1973 to 2023 using peer-reviewed journals only. Strict procedures of separating datasets assure data credibility, whereas co-word analysis and visualization help reveal theme patterns and prominent authors.
Findings: These findings present the shift in activity and key contributors in the field of actuarial accounting, including shifts in research focus and famous global contributions.
Implications/Originality/Value: This research advances scholars’ actuarial accounting knowledge in the insurance sector, which is crucial for academics, insurers, and policymakers to enhance their approaches and effectively face new challenges.
INTRATHORACIC AND EXTRATHORACIC METASTASES IN PIRLAK EWES WITH OVINE PULMONARY ADENOCARCINOMA (JAAGSIEKTE)
Authors: Dayı Belma , De Las Heras Marcelo , Sevimli Alper
Published: July 2024

Ovine pulmonary adenocarcinoma (OPA) is a contagious neoplastic disease caused by jaagsiekte sheep retrovirus (JSRV) and is characterized by chronic respiratory clinical signs. In this study we describe intrathoracic and extrathoracic metastases in Pırlak ewes naturally infected with JSRV. Two Pırlak sheep flocks brought from two different provinces had progressive respiratory distress, nasal discharge, cough, and emaciation, and nine ewes from these two flocks were necropsied at the request of the owners. Gross findings revealed purple colored and consolidated cranioventral lung lobes with scattered white nodules of various sizes. One ewe had metastasis in the mediastinal lymph node, and another had metastasis in the left kidney. Histopathological examinations of the tumors in the lungs and metastases showed papillary and acinary growth patterns. Immunohistochemically, strong JSRV-Env expression was observed in neoplastic cells.
On the Linear Complexity of Generalized Cyclotomic Sequences with Odd Period
Authors: Edemskiy V. A.
Published: July 2024

The linear complexity of new generalized cyclotomic sequences with odd period was estimated. The sequences were deﬁned using generalized cyclotomic classes composite modulo. Conditions suﬃcient for the existence of binary and non-binary sequences with high linear complexity were obtained. The earlier results on the linear complexity of sequences with the period equal to the power of a prime were generalized.
Vacation in Egypt associated with Shiga toxin-producing Escherichia coli infection in children and adolescents, northern Italy, 2023
Authors: Ria Thomas , Mancuso Maria Cristina , Daprai Laura , Liporace Maria Francesca , Gazzola Alessandra , Arnaboldi Sara , Vianello Federica , Luini Mario , Consonni Dario , Ardissino Gianluigi ,   on behalf of the ItalKid-HUS Network
Published: July 2024

Background

Haemolytic uremic syndrome (HUS) is a severe complication of infection with Shiga toxin-producing Escherichia coli (STEC). Although the reservoirs of STEC are known, the source of the infection of sporadic cases is often unknown. In 2023, we observed several cases of bloody diarrhoea with STEC infection in children and adolescents returning from vacations.

Aim

We aimed to explore the association between travel and bloody diarrhoea with STEC infection in children and adolescents.

Methods

We included all children and adolescents with bloody diarrhoea with STEC infection identified in 2023 by the ItalKid-HUS Network surveillance system in northern Italy. We interviewed children’s families and sent a questionnaire on recent travels abroad. The exposure time was between 3 days after arrival abroad and 5 days after return home. A self-controlled case series (SCCS) design was used in the analysis.

Results

Of the 43 cases, 11 developed HUS. Twenty-three cases did not travel abroad, while 20 had travelled to several destinations. The incidence rate ratio (IRR) associated with travel to Egypt was 88.6 (95% confidence interval (CI): 17.0–462). Serotype analysis excluded the possibility of a single strain causing the infections. We did not find the source of the infections.

Conclusion

There is an elevated risk of acquiring STEC infection with bloody diarrhoea and HUS associated with travel to Egypt. Specific investigations to identify the source are needed to implement effective preventive measures.
Strain-dependent variations in replication of European clade 2.3.4.4b influenza A(H5N1) viruses in bovine cells and thermal inactivation in semi-skimmed or whole milk
Authors: Palme Diana I , Lang Juliane , Helke Dajana , Kuryshko Maryna , Abdelwhab Elsayed M
Published: July 2024

We investigated the thermostability of four European avian influenza A(H5N1) viruses in whole and semi-skimmed milk and their replication in bovine kidney and lung cells amid the current influenza A(H5N1) dairy cattle outbreak in the United States. Results showed strain-dependent differences in thermal inactivation, particularly in whole milk, and variable replication efficacy in lung cells. These findings support assessing the inactivation of European H5N1 viruses in milk and their replication in bovine cells, aiding biosafety protocols and public health measures.
Early rise of West Nile fever in Israel, June 2024
Authors: Mor Zohar , Omari Husein , Indenbaum Victoria , Kirstein Oscar D , Shatach Catabi Oren , Reicher Shay , Lustig Yaniv , Davidovich-Cohen Maya , Kaliner Ehud , Sheffer Rivka , Elbaz Shirly , Kriger Or , Alroy-Preis Sharon
Published: July 2024

This report describes an unusual surge of West Nile fever in Israel in June 2024, during which 125 cases were diagnosed, compared with 4 cases on average during June in previous years (2014–23). Of the cases, 64 (62.1%) had neuroinvasive disease and 12 (9.6%) died; the 2024 case fatality rate was not significantly elevated vs the average rate in 2014–23. The early rise could be related to a temperature increase in spring and early summer of 2024.
Історія становлення й розвитку спортивної ходьби на факультеті фізичної культури, спорту та здоров’я Волинського національного університету імені Лесі Українки
Authors: Yalovyk Volodymyr , Yalovyk Anton
Published: July 2024

Topicality. Race walking has been one of the leading educational components of athletics at the Faculty of Physical Culture, Sports and Health of Lesya Ukrainka Volyn National University for decades. The development of race walking at the Faculty has played a significant role in the glorification of the famous Volyn University at international competitions of various kinds. The development of race walking at the Faculty and the results of students' performances are only partially covered in the media, and they become forgotten over the years. The Aim of the study is to analyze the historical development of race walking at the Faculty of Physical Culture, Sports and Health at Lesya Ukrainka Volyn National University. Research Methods. Historical and pedagogical analysis of archival documents, reports of sports organisations (Burevisnyk, Spartak, Dynamo, Kolos), sports club of the Faculty, School of Sports and Physical Education, sports department of Volyn Regional State Administration, survey of teachers of the Faculty, coaches and heads of sports clubs, children and youth sports schools, information resources of the Internet. Results of the Study. The analysis of archival documents of the university, interviews with teachers and the university graduates, coaches of societies that continue to train speed walkers helped to reveal the peculiarities of the origin and development of race walking at the Faculty of Physical Culture, Sports and Health. The establishment of the Faculty of Physical Education at Lesya Ukrainka Lutsk State Pedagogical Institute in 1969 contributed to the development of race walking. Over the years, the faculty has trained 28 MSU, 15 MSUMC, more than 100 KMU and 5 Olympic Games participants. During this period, the students of the Faculty won 12 gold, 9 silver and 10 bronze medals at the World Summer University Games, European and World Cups and Championships. Conclusions. The historical analysis of the development of race walking at the Faculty of Physical Culture, Sports and Health helped to identify certain achievements of the University students over the period of its activity.
Передумови для розробки концепції застосування фізкультурно-оздоровчої технології для школярів із порушенням зору в процесі адаптивного фізичного виховання
Authors: Bukhovets Вozhena , Todorova Valentina , Shchekotylina Natalia
Published: July 2024

Topicality. The existence of a forced decline in the motor activity of visually impaired students, which leads to low physical fitness indicators compared to their relatively healthy peers, causes the formation of coordination disorders that can be persistent and significantly limit their motor abilities. The Aim of the Research is to reveal the preconditions for the development of the physical culture concept and health-improving technology for 12-year-old schoolchildren with visual impairment in the process of adaptive physical education. Purpose and Methods. The research study involved 23 schoolchildren aged 12 years old. 13 – visually impaired and 10 – relatively healthy. Pedagogical study has been conducted guided by ethical principles and based on informed consent. The following methods have been used in the study: theoretical (analysis of scientific and methodological literature, theoretical analysis and generalization, system analysis); pedagogical research (experiment and testing of physical fitness indicators); standard tests were used to determine the level of physical fitness; mathematical static data processing. Results and Key Conclusions. The study of the results obtained in the group of 12-year-old relatively healthy schoolchildren showed that the majority of those performed the test of speed and agility at a sufficient level and above it. In terms of endurance, all the participants performed trunk lifts at a sufficient level, and when jumping rope, they performed the exercise at a satisfactory level more often than their visually impaired peers. Scientists argue that it is possible to improve the level of physical fitness of visually impaired students in secondary education through adaptive physical education. However, the existing programs are not adapted to the modern realities of the educational process and do not include the latest approaches and methods. All of the above determines the relevance of developing the concept of applying physical culture and health technology for visually impaired students in the process of adaptive physical education, which is the prospect of further scientific research.
Дослідження фізичного стану учнів 10-х класів ліцею спортивного профілю
Authors: Prykhodko Igor , Olkhovyi Oleh , Korchagin Mukola
Published: July 2024

Topicality. The educational and training process of specialized sports education institutions requires a systematic analysis of the physical development and the physical condition of young athletes. The Aim of the Study is to determine the level of the physical condition of 10th-grade students of the specialized sports profile lyceum based on anthropometric and medical-biological indicators and to investigate its dynamics over three years. Research Methods and Organization. The research was conducted during 2020–2022 on the basis of the Kharkiv Professional College of Sports. The anthropometric and medical-biological indicators of 10th-grade pupils of the lyceum over three years have been studied. The number of respondents was 210, and the average age of the representatives was 15,46 years. Anthropometric (measurement of anthropometric indicators) and medical-biological (spirometry, rhythm vasometry, electromanometry) research methods were applied. The level of physical condition was assessed according to the Pirogova index. One-dimensional statistical analysis according to the Student’s t-test was chosen to prove the regularities discovered in the process of research and hypothesis testing. Research Results. The study showed that the average values of the physical development indicators of the 10th-grade pupils of the lyceum of 2020–2022 years have no statistically significant differences and correspond to the rating of “average” for their age category. The average value of the physical condition index of the 10th graders of the lyceum ranges from 0,676 to 0,825 conditional units, which corresponds to the rating “above average”. However, during the three years of the study, the number of students with a “high” rating gradually decreases and the number of representatives with an assessment of the level of physical condition “above average” increases. Conclusion. Regular purposeful sports engagements and an increased level of physical activity allow ensuring a better physical condition level with average indicators of physical development. At the same time, the percentage ratio of physical condition assessments of 10th-grade lyceum pupils over three years shows a gradual deterioration of the indicator.
Вивчення мотивів та потреб до систематичних занять фітнесом жінок 35–45 років
Authors: Rymar Olha , Zaletska Anastasiia
Published: July 2024

Topicality. Women aged 35–45 are particularly aware of the significance of maintaining a healthy lifestyle, whereas health problems, such as weight gain, declining physical abilities, and decreased cognitive functioning, might arise. Fitness activities become a means of supporting and improving both physical and mental health. The study of the motives and needs that contribute to the desire and involvement in regular fitness training is one of the essential issues in physical education. The Aim of this Article is to determine the main motives and needs for regular fitness training among women aged 35–45. Material and Methods of the Research. Analysis and synthesis of scientific-methodological literature, survey, and descriptive statistics. Results of the Work. Women aged 35–45 strive to maintain their health and understand the benefits of physical activity but face health issues and fatigue. The common interests in fitness activities include knowledge of their benefits, the example set by friends, and the example set by their children. The main motivations for attending fitness classes for women aged 35–45 are improving health status, enhancing physical fitness, and increasing physical activity. Other incentives, such as improving posture, alleviating pain syndromes, body weight correction, and the opportunity to spend time enjoyably, are also significant. Conclusions. The study revealed that women aged 35–45 are highly-motivated for fitness and have a positive attitude towards a healthy lifestyle. They appreciate the beneficial impact of fitness on health and physical form. However, they encounter obstacles such as health problems and lack of time on the way to the regularity of fitness classes. It is essential to consider the above-mentioned factors when creating programs for this target audience, in particular, developing dance fitness programs that are popular among women aged 35–45.
Психічне здоров’я та посттравматичний синдром у військових залежно від участі в активних бойових діях
Authors: Shynkaruk Oksana , Byshyvets Nataliia , Dutchak Myroslav , Andrieieva Olena , Iakovenko Olena
Published: July 2024

Topicality. The issue of stress-related conditions in military personnel arises due to high workloads, danger, and psychological stress during service. There is a need to develop and implement effective methods of physical and sports rehabilitation. The Aim of the Study is to investigate the symptoms of PTSD in military personnel actively participating in combat and to identify differences in military personnel of different ages and genders. Research Methods: this study includes literature analysis, comparison, surveys, systematization, and statistical analysis methods. These statistical methods include testing data for normal distribution (Kolmogorov-Smirnov test), descriptive statistics (central tendency and dispersion Me (25; 75) conv. units), chi-square group tests, and rank dispersion analysis. The Mississippi Scale has been used to assess the severity of post- traumatic stress reactions. Participants. The study involved 4403 military personnel, 89,9 % of whom were men. The research was conducted from February 27 to April 15, 2024. Results. The average PTSD score was 69 (54; 79) points, with PTSD symptoms identified in 20.3% of the military personnel, 0,4 % of whom required urgent care. The highest average PTSD scores were observed in military personnel aged 21–30 and over 50 years, while the lowest were for those aged 41–50 years. PTSD scores in men exceeded those in women, which is associated with a higher proportion of men participating in combat. The intensity of PTSD symptoms depends on military specialty and education level. The highest PTSD scores were recorded among junior and senior officers, and the lowest among senior sergeants. Military personnel with higher education showed higher PTSD scores. Statistically significant differences in PTSD scores have been found depending on gender, combat participation, military specialty, and education. No differences have been traced based on marital status, the presence of minor children, and military experience prior to the armed conflict. Conclusion. The study emphasizes the need for targeted approaches in the rehabilitation of military personnel with PTSD.
últimas reformas de los delitos sexuales en el código penal español
Authors: Requejo Conde Carmen
Published: July 2024

La entrada en vigor en España el 7 de octubre de 2022 de la denominada ley del solo sí es sí trajo importantes novedades en los delitos contra la libertad sexual. Estas fueron la definición del consentimiento, entendido en sentido positivo, proactivo, y una inicial indiferenciación del delito de agresión y del de abuso sexual. Ambos delitos quedaron unificados en una sola tipología y castigados con la misma pena. Esta reforma convirtió la ley en una norma más favorable que la anterior, con el indeseable efecto de la excarcelación de multitud de delincuentes sexuales o la reducción de sus condenas. Ello debió corregirse solo seis meses después, promulgándose la Ley Orgánica 4/2023, que volvió a distinguir unos medios comisivos de otros en la agresión sexual,  convirtiendo en subtipo agravado la agresión sexual con violencia o intimidación, y en agravante de segundo grado la sumisión química.
Análisis de la calidad del aire en el área metropolitana de Monterrey
Authors: Luévano Hipólito Edith , Alfaro-Chacón Julian , Alvarez-Ramos Adriana , Álvarez-Sosa Sara D. , Mellado-Lira Emireth A
Published: July 2024

El área metropolitana de Monterrey (AMM) es considerada una de las más contaminadas de México. Por lo que, con el objetivo de analizar la distribución de los contaminantes criterio en el aire: PM10, PM2.5, CO, O3, SO2 y NO2 del AMM, se registró su concentración en los últimos tres años en 14 estaciones de monitoreo durante las temporadas: invierno, primavera, verano y otoño. De acuerdo con el análisis, las concentraciones de O3, CO, NOx y SO2 resultaron significativamente afectadas por el año, temporada y estación analizada; mientras que, para PM (2.5 y 10) solo la temporada y estación resultaron significativas.
PHYTOCHEMICAL ANALYSIS OF ANDROGRAPHIS PANICULATA LEAF FOR THEIR ANTIBACTERIAL AND ANTIOXIDANT POTENTIAL
Authors: Khatun Rojina , Sengupta Sudeshna , Bhattacharya Malavika
Published: July 2024

Background: Andrographis Paniculata, a herbaceous plant of the Acantharean family, is referred to as the "king of bitters" and is rich in bioactive chemicals. Andrographis Paniculata is a medicinal plant that has been used for many years in traditional medicine. Numerous bioactive substances found in the plant, including polyphenols, flavonoids, and diterpenoids, are responsible for its wide range of pharmacological effects. To assess the antibacterial and antioxidant activity of Andrographis Paniculata leaf extracts, a thorough phytochemical investigation was carried out in this work. Often referred to as the "king of bitters," Andrographis paniculata is a medicinal plant that has been used for many years in traditional medicine. Numerous bioactive substances found in the plant, including polyphenols, flavonoids, and diterpenoids, are responsible for its wide range of pharmacological effects.Aims: This study aimed to investigate the phytochemical composition of Andrographis Paniculata leaves and evaluate their potential antibacterial and antioxidant activities.Materials and Methods: The leaves of Andrographis Paniculata were collected, dried, and subjected to sequential extraction using various solvents including methanol, ethanol, and water. The phytochemical composition of the extracts was determined through qualitative and quantitative analyses to identify the presence of flavonoids, tannins, flavanols, and polyphenols. The antibacterial potential of Andrographis Paniculata, leaf extracts was assessed against six pathogenic bacteria including both gram positive and gram-negative strains by determining minimum inhibitory concentration and zone of inhibition. The extracts inhibited the growth of these bacteria and also induced bacterial cell death. Zone of inhibition values were compared with control in concentration 20 mμg /ml.Result: The growth of both Gram-positive and Gram-negative bacteria is inhibited by the ethanol extract. The antioxidant ability of leaf extracts was evaluated using assays such as 2, 2-diphenyl-1-picrylhydrazyl (DPPH), and vitamin C. The results show that when oxidized, the DPPH produces a persistent purple radical.Conclusion: Andrographis paniculata leaf extracts have been shown in this study to have excellent antibacterial and antioxidant properties, highlighting the plant's therapeutic value as a source of naturally occurring bioactive chemicals. These results add to the increasing amount of data that supports the traditional medicine practice of using Andrographis paniculata and shed light on the uses of the plant in the creation of new antioxidant and antibacterial agents.