bluuebunny/crossref_metadata_2025 huggingface dataset:
Developing a novel therapeutic strategy against cancer stem cell heterogeneity and plasticity
Authors: Kondo Toru
Published: September 2024

Cancer consists of heterogeneous cells, including cancer stem cells (CSCs), cancer cells, and tumor-associated cells, such as immune cells and vascular cells. Considering that these diverse cell types influence one another directly and indirectly through membrane proteins and secretion factors, such as exosomes and growth factors, the overall heterogeneity affects tumorigenicity and resistance to therapy. This review explores cancer heterogeneity, focusing on CSC heterogeneity, and discussed how the heterogeneity emerges by the intrinsic mechanism and the external factors and affects response to therapy. Additionally, as a potential therapeutic strategy to address this heterogeneity, I propose new Adeno-associated virus carrying a miRNA-dependent CSC eradication system that targets all types of CSCs with minimizing side effects.
A Sentiment Analysis of Customer Product Review Based on Machine Learning Techniques in E-Commerce
Authors:   Tata Consultancy Services, Senior Solution Architect, USA, Patra Gagan Kumar
Published: September 2024

The use of customer evaluations as a basis for purchasing decisions has grown in importance with the meteoric rise of e-commerce in the last several years. Reviews provide businesses with valuable information and foster trust, in addition to helping potential customers make informed decisions.
Elevating Healthcare ETL Quality: The Role of Automated Testing in Ensuring Data Excellence
Authors:   Senior Solution Specialist, Deloitte Consulting LLC, 633 Cranford Dr, Pineville, NC, Unites States - 28134, Singu Santosh Kumar
Published: September 2024

Data quality significantly impacts patient care, operational efficiency, and regulatory compliance in healthcare. Extract, Transform, and Load (ETL) processes connect and manage healthcare data, yet data quality is difficult to maintain
AJDODLARIMIZ BOY ILMIY MEROSINING О‘ZBEKISTONDA MA’RIFATLI JAMIYAT QURISH HAMDA YOSHLAR TARBIYASIDA TUTGAN О‘RNI
Authors: Tog‘ayev Nodirjon
Published: September 2024

Ushbu maqolada ajdodlarimizning jahon ilm-fani hamda sivilizatsiyasiga qо‘shgan bebaho hissasi va bizga qoldirilgan boy ilmiy-ma’naviy merosi xalqimiz uchun eng ulug‘ qadriyat ekanligi yoritib berilgan. Shu bilan birgalikda ajdodlarimizning boy ilmiy merosi xalqimizning ma’naviy yuksalishida, О‘zbekistonda ma’rifatli jamiyat barpo etishda, ayniqsa yoshlar ta’lim-tarbiyasida tutgan о‘rni tahlil qilingan.
“АДАБ АЛЬ-ТАБИБ” КАК ИСТОЧНИК НАЦИОНАЛЬНОЙ БИОЭТИКИ
Authors: Агзамова Нилюфар
Published: September 2024

В статье анализированы взгляды восточно-мусульманских мыслителей, в частности представления Ибн Сино, так как объективная история и этика философии и медицины нуждается в более скрупулезном изучении наследия отечественных ученых, чтоб через их творчество обосновать современные принципы биомедицинской этики.
DEMOKRATIK JAMIYAT TARAQQIYOTIDA IJTIMOIY G‘OYALAR EVOLYUTSIYASI VA MODERNIZATSIYASI
Authors: Nabiyev Mansur
Published: September 2024

Ijtimoiy g‘oyalar evolyutsiyasi va modernizatsiyasi faqat sof nazariy yoki ijtimoiy jarayonlargina bo‘lib qolmay, shu bilan birga xalqning turmush tarzi, madaniy an’analari, urf-odatlari va uning ruhiy xususiyatlarini ham o‘z ichiga oladi.  Ushbu maqolada demokratik jamiyat taraqqiyotida ijtimoiy g‘oyalar evolyutsiyasi va modernizatsiyasining asosiy jihatlari, o‘ziga xos xususiyatlari yoritib berilgan.
GLOBALLASHUV SHAROITIDA MILLIY MADANIYAT SOHASIDAGI O‘ZGARISHLARNING O‘ZIGA XOS JIHATLARI
Authors: Kenjayeva Dilrabo , Xaydarova Larisa
Published: September 2024

Jahonda globallashuvning yangi bosqichida dunyo mamlakatlari o‘rtasidagi madaniy-iqtisodiy aloqalarni yanada chuqurlashishi, albatta, iqtisodiy o‘sish va turli madaniyatlarni boyitishga yordam beradi, biroq globallashuv sharoitida milliy madaniyatlarni modernizatsiyalashishi va integratsiyalashishi natijasida sodir bo‘layotgan o‘zgarishlarni o‘rganish dolzarb masalalar qatoriga kiradi.
Narasi Realisme Magis dalam Novel Mustika Zakar Celeng Karya Adia Puja
Authors: Andriana Wahyu Dian , Rengganis Ririe , Sudikan Setya Yuwana
Published: September 2024

This research aims to describe Wendy B Faris' forms of magical realism in the novel Mustika Zakar Celeng by Adia Puja, including 1) irreducible magical elements, 2) phenomenal world, 3) unsettling doubts, 4) incorporation of nature, 5) disruption of space, time, and identity, and 6) magical realism narrative in the novel Mustika Zakar Celeng. The research approach used in this study is a qualitative approach with descriptive method. The data source used, namely the novel Mustika Zakar Celeng by Adia Puja with data in the form of words, phrases, sentences, and paragraphs relevant to the research focus. The data collection techniques used in this research are listening and recording techniques. Meanwhile, the data analysis technique used is hermeneutic technique. Based on the results of the research, it shows that the novel Mustika Zakar Celeng contains five elements of magical realism, including 1) five data of irreducible elements, 2) three data of phenomenal world, 3) two data of unsettling doubts, 4) three data of world merging, and 5) four data of interference with time, space, and identity.  The relationship between the five elements can be seen in the characters of Kang Kopral, Tobor, and Ki Ama Hudlan as real characters who interact with the Queen of Siluman Celeng as a magical character. All of these elements are interconnected and continuous, forming a series of magical realism.
Kata Kunci:
Myth;
Wendy B Faris' Narrative of Magical Realism;
Mustika Zakar Celeng Novel;
Reformas y Retos en la Suspensión Condicional de la Pena en Ecuador
Authors: Ruiz Castillo Santiago Vinicio , Castillo Álvarez Pablo José
Published: September 2024

El presente estudio profundiza la temática de la Suspensión Condicional de la Pena en el contexto ecuatoriano, mecanismo previsto en el Código Orgánico Integral Penal. Se investigan los factores que restringen su empleo por las partes involucradas en el proceso judicial, subrayando la necesidad de superar las barreras identificadas para mejorar la efectividad de este recurso. Este análisis apunta a ofrecer una perspectiva crítica que contribuya a la optimización de las prácticas penales, enfatizando la relevancia de adaptaciones legales y procedimentales que faciliten una justicia más eficiente y equitativa en Ecuador.
AI-Driven Predictive Models for Early Detection of Diabetes: A Review Study
Authors: Giri Srishti
Published: September 2024

Diabetes is a chronic condition with profound global health implications, making early detection critical for effective management and prevention of complications. This paper offers a comprehensive review of AI-driven predictive models for diabetes detection, highlighting their evolution, current trends, and clinical relevance. The review traces the progression from early statistical methods like logistic regression to sophisticated machine learning and deep learning approaches, such as neural networks and gradient boosting machines. These AI techniques have significantly enhanced the accuracy of diabetes risk prediction by leveraging diverse data sources, including electronic health records (EHRs) and continuous glucose monitoring (CGM) devices. The review also explores the integration of multi-omics data, further refining predictive capabilities. Case studies demonstrate the real-world impact of these models, showing substantial improvements in early detection and personaliSed treatment. However, challenges persist, particularly in data security, interdisciplinary collaboration, and ethical AI deployment. This review identifies existing research gaps and proposes future directions, emphasizing the ongoing need for innovation in predictive modelling. The insights provided are intended to inform researchers, clinicians, and policymakers in advancing AI-driven strategies for diabetes prediction and prevention.
Enhancing Agricultural Sustainability in Geographically Isolated and Disadvantaged Areas (GIDA): A Study on Awareness, Perceptions, and Information-Communication-Education (ICE) Interventions for Organic Fertilizer Adoption in Digkilaan, Iligan City
Authors: Aque Annabeth , Guiritan Almira Faye , Nabua Edna
Published: September 2024

This research study focuses on enhancing agricultural sustainability in Geographically Isolated and Disadvantaged Areas (GIDA), specifically in Digkilaan, Iligan City. Through a comprehensive investigation, the study assesses the awareness and perceptions of residents regarding organic fertilizer usage. The research incorporates Information-Communication-Education (ICE) interventions, including seminars and workshops, to promote the adoption of organic farming practices. Findings reveal positive attitudes towards organic fertilizer, with a notable knowledge gap addressed through the ICE campaign. The study recommends expanding educational initiatives, strengthening government support, and encouraging community engagement to foster the sustainable integration of organic farming practices in Digkilaan.
Customer Satisfaction among J&T Users in Terengganu
Authors: Sidik Siti Noor Aishah Mohd , Sukor Hanis Athirah Abd , Atiqah Nur Fatwa , Saedon Aiezwa Zetty Syafina , Apandi Fatin Syafiqah Mohd , Rahim Muhammad Kamal Fudhail Mohd
Published: September 2024

Service delivery plays a vital role since the buying behavior has changed. The customer prefers to buy products online and expects products to be delivered on time and in the best condition. This phenomenon is a challenge to the company to always maintain the best service to the customer and compete with other competitors. This study wants to identify the factors that influence satisfaction among J&T users. The service quality dimension, which is tangibility, reliability, assurance, empathy, and responsiveness, is all under investigation. This sample of this study consisted of J&T uses from Terengganu. 300 questionnaires were distributed to respondents via online, and 249 data were collected and usable. The questionnaire feedback was analyzed using SPSS to access the regression effect of each research variable. The study discovered that tangibility, reliability, empathy, and responsiveness influence customer satisfaction. Regression analysis also proven that empathy is the most critical factor impacting customer satisfaction. The findings as a guideline for service delivery companies to always upgrade the service to the customers.
Conflict Dynamics and Obstacles to Peace in the Lake Chad Basin: Analysis and Perspectives for a Positive Dynamic of Peace.
Authors: Fouodji Dezo
Published: September 2024

The recurrence of conflicts in the Lake Chad basin positions this region in the high-risk zone of the African Sahel, described by researchers of the Center of Progress as “arc of tension”. Focusing on the southern shore of the lake, this article is based on analyses of the documentary content of scientific works dealing with conflicts in the Lake Chad basin, the results of research and scientific articles also devoted to the same issues, and empirical data was collected from community members (through personal interviews) in order to understand the process of renewal of conflict dynamics in this ecological basin. It also draws on the work of Thomas Homer-Dixon and his Toronto research group to demonstrate that the resurgence of conflict in this basin is attributable to the mismatch between the need for vital resources and the supply, as well as to the inadequacy of national and community instruments for regulating natural resources. The article attempts to answer the following questions: what explains the recurrence of conflicts in the Lake Chad basin? And what are the obstacles to peace in this area? Firstly, it shows how the activities of cross-border criminals, the Islamist sect (Boko Haram) and the scarcity of natural resources are fueling the process of renewed conflict dynamics in the Lake Chad Basin. It then identifies the factors blocking peace in this ecological basin, in particular the difficulty of access to land and natural resources, the scarcity of economic resources, the competition between social groups for access to and control of resources, and the system for managing these resources. Finally, as a way out of the conflicts circle in this region, the article proposes an environmental mediation approach based on the promotion of incentive mechanisms for the sustainable and concerted management of natural resources and the creation of a community of interests to strengthen peaceful cohabitation between peoples, with the aim of building a positive dynamic of peace.
Evaluation of Teacher Training in Integration of ICT in Teaching Public Secondary Schools in Tigania West, Meru County, Kenya
Authors: Ngaya Nancy Mukiri , Omae Hilda , Thuranira Mercy
Published: September 2024

Kenya has experienced significant growth in the incorporation of ICT into secondary school curricula in recent years. The Kenyan government has implemented numerous initiatives to enhance this. Information and Communication Technology integration in secondary school teaching and learning environments remains incomplete due to several factors. These include inadequate infrastructure, limited teacher training, resistance to change, and insufficient government policies supporting ICT implementation. Additionally, financial constraints prevent schools from acquiring the necessary technologies, and there is often a lack of ongoing technical support. Despite the growing recognition of ICT’s importance in enhancing learning outcomes, these challenges hinder its full adoption, leaving many schools without effective digital learning environments. Several experts contend that the mere installation of technical equipment and infrastructure would not inherently result in the incorporation of ICT in schools unless the teachers receive proper training on how to utilize the technologies. This study aimed to investigate the impact of teacher training on the incorporation of ICT in the instruction of public secondary schools. The study utilized a descriptive survey approach. The sample consisted of 50 public secondary schools, 50 principals, 100 heads of departments, and 200 teachers. The study utilized a stratified random sampling technique to choose schools. The purposive sampling technique was employed to assess school principals, heads of departments, and teachers. The study included a total of 105 participants, consisting of 15 administrators, 30 heads of department, and 60 teachers. Data gathering involved the utilization of questionnaires, interview schedules, and observation checklists. The quantitative data was analyzed using statistical methods such as calculating means, frequencies, and percentages. The interviews yielded qualitative data, which was evaluated using content analysis. The study determined that the training of teachers in ICT had a beneficial and substantial impact on its incorporation into the educational process. The study proposes that it is essential for all instructors to receive specialized training on the utilization of ICT in their teaching practices. One way to accomplish this is by implementing a teacher training curriculum that includes specific content on ICT pedagogy. The Ministry of Education should offer professional development programs in information and communication technology for teachers, as this will enable them to acquire ICT skills. Additional research is required to determine the level of preparedness of secondary school teacher trainers in equipping secondary school teachers with ICT skills. Incorporating integration into the process of teaching and learning.
PERSPECTIVAS DO ENDOLIFT COM LASER DE DIODO 1470NM NO TRATAMENTO DA GORDURA SUBMENTONIANA: UMA ANÁLISE BIBLIOGRÁFICA
Authors: Wakabayashi Yoshiko , Lopes Sobral Jacqueline , Manoel Rodrigues Fabrizio , Ferraz João Rafael
Published: September 2024

O artigo tem como objetivo apresentar uma revisão de literatura sobre o uso da tecnologia a laser Subdérmico de 1470nm para tratamento de gordura submentoniana, a partir de artigos científicos e casos clínicos descritos na literatura. Revisão bibliográfica: A gordura submentoniana é o acúmulo de gordura abaixo do queixo que faz com que concavidade cervicofacial diminua e leva à perda da elasticidade. A busca por novas tecnologias que entreguem resultados através de técnica segura com eficiência comprovada fez com que muitos estudos sobre o endolaser ganhassem destaque. Conclusão: O laser de diodo de 1470nm é uma tecnologia aplicada na gordura submentoniana que atua na redução da adiposidade e flacidez tecidual de maneira eficiente, segura, inovadora e com rápida recuperação.
PREVALÊNCIA DE ACIDENTES COM SERPENTES PEÇONHENTAS NOS ESTADOS DO RIO DE JANEIRO E MINAS GERAIS ENTRE 2017 E 2022
Authors: Oliveira Millena Silva de , Costa Alexandre de Pina , Cordeiro Julia Adolpho de Jesus , Barros Letícia Lira , Moreira Lucas Raphael Romero Suane , Vairo Leonardo Rodrigues , Ongaratto Lorenna Pontes , Santos Isabella Lacerda Calheira dos , João Millena Guimarães , Silva Leticia Vale da , Moraes Rocheli Jacques , Reis Maria Fernanda Miranda dos , Costa Maria Clara Barbosa Alencar
Published: September 2024

Foi realizado um estudo epidemiológico do tipo observacional analítico ecológico para compreender a prevalência de acidentes com serpentes peçonhentas nos estados do Rio de Janeiro (RJ) e Minas Gerais (MG) entre 2017 e 2022. Os agravos causados por animais peçonhentos são uma grande preocupação no Brasil, sendo a principal causa de intoxicação em humanos. Esses incidentes resultam em complicações graves, podendo levar à morte. Assim, foram analisados os gêneros Crotalus (cascavel), Bothrops (jararaca), Lachesis (surucucu) e Micrurus (coral verdadeira), obtendo resultados destas variáveis: Acidentes por Estado e por Sexo, Sazonalidade, Faixa Etária, Tipo de Serpente e Evolução dos casos. Nesse sentido, MG apresentou maior incidência de acidentes e maior disparidade entre os gêneros em relação ao RJ. Observamos uma tendência de aumento de casos entre os meses de fevereiro a março e uma predominância do gênero Bothrops. Esses dados contribuem para entender os agravos de serpentes, além da vigilância e controle no Brasil, pois auxiliam as estatísticas epidemiológicas e pesquisas estratégicas dentro do Sistema Único de Saúde (SUS). Ademais, criam base para o desenvolvimento de intervenções públicas voltadas à prevenção e ao tratamento desses agravos, contribuindo para melhoria da saúde pública e para redução do impacto desses incidentes na população.
GESTÃO ESCOLAR: TRAÇANDO O PERFIL DA GESTÃO DESENVOLVIDA EM UMA ESCOLA DA REDE ESTADUAL DE ENSINO DE MANAUS-AM
Authors: Farias  Lima Eli
Published: September 2024

A presente investigação aborda a questão da gestão escolar e explora conceitos associados à autonomia, competência e liderança na educação. A partir da proposta de estilo de gestão que se situa hoje, procura-se identificar os estilos de liderança adequados para os espaços educacionais que desejam implementar a liderança democrática. Sua finalidade é reconhecer as competências individuais necessárias à atuação do diretor (a) escolar, que é o profissional responsável por administrar os aspectos administrativos, pedagógicos, sociais e políticos da escola. A partir deste ponto de partida, buscou-se fundamentos teóricos que nos permitissem estudar o objeto. Trata-se de um estudo de natureza quali-quantitativa, o sujeito principal da investigação foi o diretor(a) da escola. O objetivo desta pesquisa não foi traçar o perfil da gestão escolar desenvolvida em uma escola da rede estadual de ensino da cidade de Manaus-AM. Os resultados do estudo permitiram deduzir que os processos de gestão escolar contornaram a questão administrativa e colocaram a escola num local simultaneamente educativo e recreativo, tornando-se a instituição num local de aprendizagem significativa e de atividade comunitária, esta última facilitada pela democratização das relações institucionais e pela participação ativa da comunidade. No entanto, existem numerosos obstáculos a superar para se alcançar uma liderança democrática e participativa.
POLÍTICAS PÚBLICAS DE ENFRENTAMENTOS À VIOLÊNCIA DOMÉSTICA
Authors: Mello dos Santos Grasiele , Eugenio da Cruz Claudio
Published: September 2024

Este artigo tem como propósito iniciar uma reflexão teórica acerca da violência de gênero, conectando-a com as abordagens das políticas governamentais para o seu combate. Para isso, destacamos a importância de políticas públicas, que são essenciais para lidar de forma eficaz e consistente com a violência de gênero. Com o intuito de atingir tais objetivos, iremos abordar o exemplo da Rede de Atenção à violência contra as mulheres, que busca elaborar estratégias preventivas eficazes e políticas que visam assegurar a autonomia das mulheres e seus direitos humanos, responsabilizar os agressores e fornecer atendimento especializado às mulheres que sofrem violência. O objetivo deste estudo é promover uma discussão entre os dados coletados sobre violência doméstica em nível nacional e as iniciativas de segurança implementadas para lidar com os casos de violência contra a mulher no âmbito familiar. Dessa forma, ao analisar de forma mais detalhada a implementação de políticas públicas dedicadas a esse tema, levando em consideração a influência dos movimentos feministas nesse contexto, busca-se avaliar as ações recentes do governo em resposta ao problema da violência contra a mulher, destacando os desafios enfrentados no sistema de justiça criminal convencional.
PROJETO CRIANÇA FELIZ: UMA ABORDAGEM RECREATIVA REFERENTE AO DIA DAS CRIANÇAS POR ESTUDANTES DE MEDICINA
Authors: Nascimento da Fonseca Filho José César , Pontes Carneiro Monalyza , Domingos de Sousa Oliveira Leonardo , De Souza Rodrigues Letícia Vitória , Linhares Sousa Eliciane Maria , Nunes Turbano Myrella Evelyn , De Sousa Morais Maria Clara , Freres Holanda Pedro Henrique , Mendes de Souza Romulo , Barbosa Oliveira Feitosa Melice , De Souza Carlos Camilo Magno
Published: September 2024

As Ligas Acadêmicas de Medicina são entidades constituídas fundamentalmente por estudantes, sem fins lucrativos e voltadas para o estudo de assuntos, ou de áreas específicas da Medicina. Dentro do eixo de extensão é possível aplicar, na prática, os conhecimentos obtidos durante a graduação com os mais diversos públicos. Em face disso, destacam-se as atividades lúdicas, por possuírem um impacto positivo em relação à educação em saúde, principalmente com o público infantil. Metodologia: O estudo em questão constitui um relato de experiência com caráter descritivo, o qual pretende descrever e avaliar uma atividade de extensão realizada pela Liga Acadêmica de Urgências e Emergências Pediátricas (LAUEP-IESVAP). Relato De Experiência: A COPPEXI promoveu uma ação para o dia das crianças que ocorreu no IESVAP, com as crianças e responsáveis da comunidade Mãe Rainha. A LAUEP em parceria com a LACITRE, desenvolveu de forma didática o ensino para as crianças de como reconhecer uma situação de engasgo no cotidiano e como realizar a manobra de Heimlich. Acompanhamos de perto também o desenvolvimento das crianças em outras atividades realizadas por outras ligas e núcleos acadêmicos. Considerações Finais: O projeto Criança Feliz faz possível a reflexão sobre as experiências vivenciadas e os impactos gerados durante todo o processo. Em sequência, pôde-se observar a importância da integração entre a área da saúde e a comunidade, especialmente no contexto infantil. Além disso, a presente abordagem recreativa mostrou-se uma ferramenta eficaz para promover a saúde integral das crianças, indo além da perspectiva tradicional médica.
ASSOCIAÇÃO ENTRE HEMORRAGIA SUBARACNÓIDEA E SÍNDROME DE TAKOTSUBO: CORRELAÇÕES CLÍNICAS, COMPLICAÇÕES E INCIDÊNCIA CONCOMITANTE
Authors: Almeida Ferreira Ana Júllia , Da Silva Mendonça Helena , Sanches de Carvalho Mariana , Teixeira Nunes Yasmin
Published: September 2024

A hemorragia subaracnóidea (HSA) e a síndrome de Takotsubo (ST), também conhecida como cardiomiopatia de estresse, são condições clínicas distintas que afetam o sistema cardiovascular e neurológico, respectivamente. Recentemente, têm surgido evidências que sugerem uma inter-relação entre a HSA e a síndrome de Takotsubo.  Objetivo: explorar a conexão entre a hemorragia subaracnóidea e a síndrome de Takotsubo. Materiais e métodos: trata-se de uma revisão integrativa, em que a questão norteadora foi “A associação entre Síndrome de Takotsubo e hemorragia subaracnóidea é mais grave para o paciente acometido em termos de recuperação neurológica, função cardíaca, taxa de complicações e mortalidade?”. A busca pelos artigos ocorreu no PubMed a partir dos termos “subarachnoid hemorrhage” e “takotsubo syndrome”, combinados entre si por operadores booleanos. Resultados e discussão: estudos prospectivos recentes confirmaram que o ST é uma complicação relativamente comum da HSA aguda, ocorrendo em até 28% dos casos. Na HSA, a ST está associada a um risco aumentado de complicações cardíacas e não cardíacas. Relatórios anteriores sugerem que o ST é um fator de risco para arritmias, edema pulmonar e isquemia cerebral atrasada na HSA. Conclusão: Nosso estudo concluiu que a incidência de Síndrome de Takotsubo em pacientes com hemorragia subaracnóidea é variável chegando até a 30%, com predominância significativa em mulheres. A gravidade da HSA foi significativamente maior em pacientes com ST do que naqueles sem a síndrome.
EFICÁCIA DA OXIGENOTERAPIA HIPERBÁRICA NO TRATAMENTO DE PIODERMA GANGRENOSO
Authors: Almeida Ferreira Ana Júllia , Macedo Torrente Natally , Custódio Martinez Sacchi Pedro Paulo , Pezzotto Poliana
Published: September 2024

O pioderma gangrenoso (PG) é uma condição dermatológica rara e severa, caracterizada por úlceras necrosantes que frequentemente evoluem para lesões extensas e dolorosas. Nos últimos anos, a oxigenoterapia hiperbárica (OHB) tem surgido como uma opção terapêutica promissora para uma variedade de condições médicas, incluindo lesões crônicas e doenças inflamatórias. Objetivo: explorar a eficácia da oxigenoterapia hiperbárica no tratamento do pioderma gangrenoso. Materiais e métodos: trata-se de uma revisão integrativa, em que a questão norteadora foi “Em pacientes com pioderma gangrenoso, como a oxigenoterapia hiperbárica é eficaz em termos de taxa de cicatrização das lesões, redução da dor e tempo de tratamento?”. A busca pelos artigos ocorreu no PubMed a partir dos termos “hyperbaric oxygen therapy” e “pyoderma gangrenosum, combinados entre si por operadores booleanos. Resultados e discussão: A oxigenoterapia hiperbárica consiste na inalação de 100% de oxigênio enquanto o paciente está no interior de uma câmara hiperbárica a uma pressão mais alta do que a atmosférica, favorecendo o processo de cicatrização do tecido danificado. Esta terapia demonstrou tratar efetivamente as úlceras de PG e reduzir a dor associada à PG. Conclusão: Apesar de não ter ensaios controlados confirmando a eficácia da oxigenoterapia hiperbárica em PG, vários relatos de caso apontam os benefícios dessa terapia sozinha ou como adjuvante.
Transformational learning experiences on productive-failure approach in Mamthematics
Authors: Luzano Jay Fie
Published: September 2024

A learning failure is not always a denial of knowledge but an opportunity to be productive in the academic pursuit in the field of mathematics. This qualitative case study explored the students’ experiences with the utilization of the Productive-Failure Approach in teaching Mathematics. This employed thematic analysis to analyze the qualitative data from the ten (10) BSEd Mathematics students via Individual Interviews and Focus-Group Discussion. Findings revealed four (4) emergent themes on the utilization of the productive-failure approach in mathematics: (1) prior knowledge activation in mathematics; (2) engaging mathematics learning processes; (3) exerting effort in learning mathematics; and (4) involvement and interaction in learning mathematics. The findings of this study signify that the use of the Productive-Failure Approach helped the students thrive in the learning process; thus, it is recommended that mathematics teachers strengthen their utilization of the Productive-Failure Approach in teaching Mathematics.
Technostress Creators and Inhibitors on the Psychological Well-Being Of Tertiary Educators in the State Universities in CALABARZON Region, Philippines
Authors: Manabo Carlo Emil , Buena Maria Corazon A.
Published: September 2024

This study determined the demographic profile of the tertiary educators, their level of technostress creators and inhibitors, and the level of their psychological well-being. Likewise, the correlation among the said variables were also identified. A descriptive-correlational research design was employed in the study with a total of two hundred thirty-one (231) regular faculty members as participants. Frequency count and percentage, median, and Spearman's Rank-Order correlation were used to analyze the gathered data. Results revealed that most of the participants are in the middle age of their career, female, taking their PhD units, are in the assistant professorial level, have been connected in the university for sixteen years and above, and majority have no ICT related training attended for academic year 2023-2024. Findings also revealed that there was a low level of technostress creators and a high level of technostress inhibitors in the state universities in the region. Furthermore, findings revealed that the tertiary educators have a high level of psychological well-being in all of its aspects. Further, the results showed a significant negative correlation between the level of technostress creators and the level of psychological well-being; and a significant positive correlation between the level of technostress inhibitors and the level of psychological well-being of the tertiary educators. Thus, it only means that to improve the level of psychological well-being of the tertiary educators, the level of technostress creators must be reduced and the level of technostress inhibitors must be strengthened. This will ensure the continuous integration of ICTs in education by the tertiary educators for a technology-driven education in CALABARZON region.
BÜTÇE AÇIĞI BELİRSİZLİĞİNİN BELİRLEYİCİLERİ: FARK VE SİSTEM GMM YAKLAŞIMINDAN ELDE EDİLEN KANITLAR
Authors: Çobanoğulları Gökhan , Erkam Serkan
Published: September 2024

Bu çalışmada, 1992-2016 döneminde 48 ülke için politik, ekonomik ve mali değişkenlerin bütçe açığı belirsizliği üzerindeki etkisi dinamik panel veri yöntemi (fark ve sistem GMM) kullanılarak analiz edilmektedir. Çalışmanın amacı, bütçe açığı belirsizliğini belirleyen faktörleri ampirik olarak incelemek, bu belirsizlik ile kamu harcamaları ve kamu gelirleri arasındaki nedensellik ilişkisini analiz etmektir. Bulgular, enflasyonun bütçe açığı belirsizliğini pozitif yönde, ekonomik büyümeyi ise negatif yönde etkilediğini göstermektedir. Kamu harcamaları ise bütçe açığı belirsizliğini pozitif yönde, kamu gelirlerini negatif yönde etkilemektedir. Bütçe açığı belirsizliği üzerindeki etkisi açısından ise, kamu harcamalarının kamu gelirlerine baskın olduğu sonucuna ulaşılmaktadır. Bu sonuç, kamu borçluluğu arttıkça bütçe açığı belirsizliğinin de artması bulgusuyla desteklenmektedir. Politik ve kurumsal faktörlerin etkisi incelendiğinde, politik risk azaldıkça bütçe açığı belirsizliğinin arttığı görülmektedir. Bu durum, demokrasi seviyesinin artmasıyla kamu harcamalarının artması ve bütçe dengesinin bozulması ile açıklanmaktadır. Nedensellik testleri, kamu gelirleri ile harcamaları arasında çift yönlü bir nedensellik olduğunu ve bütçe açığı belirsizliğinin bu sonucu değiştirmediğini göstermektedir. Genel olarak, kamu gelir ve giderlerinin planlanması ve ilgili kurumların iş birliği yapmasının bütçe açığı belirsizliğini azaltmada önemli olduğu sonucuna varılmaktadır.
Antikçağda Ordu Bölgesindeki Madencilik Faaliyetleri
Authors: Oy Harun
Published: September 2024

Ordu ilinin iç kısımlarında, özellikle Mesudiye çevresindeki yerleşmelerde belirlenen madeni alet ve cüruflar MÖ. 3. Binyıldan itibaren bölgedeki toplulukların madencilikle uğraştıklarına işaret etmektedir. Bölgede çok geniş alanlarda bulunan bakır, kurşun, çinko, gümüş, demir ve altın yatakları sebebiyle madencilik faaliyetleri bakımından bölgenin 5000 yıllık bir geçmişe sahip olduğu değerlendirilmektedir. Ordu ilinde en azından İlk Tunç Çağından beridir madeni buluntulara rastlanmaktadır. Bölgedeki Demir Çağı (MÖ. 1. binyıl) yerleşimlerinde yoğun maden cüruflarının varlığı, antik kaynakların Homeros’tan başlayarak bölgedeki madenlerden söz ediyor olması, MÖ. 6. Yüzyıldan itibaren antik kaynaklarda demirden ve Khalip’lerden söz edilmesi, Roma, Bizans ve Ortaçağdan günümüze kadar bölgede var olan madenler hakkında devamlı bilgiler bulunması, günümüzde de bu zengin madenlerin işlenmeye devam edilmesi Ordu çevresindeki güçlü madencilik faaliyetlerinin tarihsel kökenlerinin çok eskiye gitmesiyle bağlantılıdır. Ordu bölgesinde Kabadüz ilçesindeki Haramiköy ve Akgüney mahalleleri ile merkeze bağlı olan Gümüşköy çevresinde yapmış olduğumuz incelemelerde çok eskilere gitmesi muhtemel madencilik faaliyetlerine işaret eden ocak ve galeriler bulunmaktadır. Ocaklarda iptidai yöntemlerle madencilik yapıldığı ocakların durumundan anlaşılmaktadır. Yöre halkı da zaten madenci topluluklardan oluşmakta ve geçimlerini bu şekilde sağlamaktadırlar. Antik çağlarda bölgede yaşayan toplumların böyle sarp bir coğrafyaya yerleşmesi için madenlerin varlığı etkili olmuş olmalıdır. Ordu ilinin iç kısımlarındaki dağlık bölgelerde çıkarılan madenler Tokat ve Sivas bölgelerine gönderilmekte olduğu, Karadeniz sahillerine yakın olan madenlerin ise Kotyora (Ordu) üzerinden ihraç edilmiş olduğu ortaya çıkmaktadır.
Determining the Trends in Global Citizenship Publications in Education: A Bibliometric Analysis
Authors: Erdoğan Erdi , Temel Ayşenur
Published: September 2024

Although numerous educational studies have been conducted on global citizenship, a significant gap in the literature needs to improve a comprehensive understanding of global citizenship research in education. Therefore, this study aims to employ a bibliometric method to analyze the academic production of global citizenship in education. In line with this purpose, the data from 2000 to 2022 were obtained from the Web of Science database, and an analysis encompassing annual scientific production, cited documents, sources, authors, affiliations, countries, keywords, research trends, and conceptual structure was conducted. Furthermore, predictions were made regarding the future of global citizenship research. Analysis was performed by using the Biblioshiny interface via RStudio. It is concluded that global citizenship research has shown a strong upward trend since 2008. Notably, the United States and the United Kingdom have emerged as central contributors in the field of global citizenship. Global citizenship research is evolving towards the global citizenship education dimension. In particular, there is a focus on internalization of the curriculum to develop global sensitivity. In future research, sub-themes of global citizenship can be tested using different artificial intelligence tools.
Cloud Computing: Revolutionizing IT Infrastructure with On-Demand Services and Addressing Security Challenges
Authors: Suraj Patel
Published: September 2024

Cloud computing has emerged as a revolutionary computing paradigm that integrates virtualization, parallel and distributed computing, utility computing, and service-oriented architecture. This model allows enterprises to leverage scalable and flexible IT infrastructure, reducing capital expenditures and operational costs. Cloud computing offers various services such as Infrastructure as a Service (IaaS), Platform as a Service (PaaS), and Software as a Service (SaaS), providing computing resources on-demand with a pay-as-you-go pricing model. Popular commercial implementations include Amazon’s EC2, Google App Engine, and Salesforce’s CRM system. While cloud computing offers immense benefits in terms of cost efficiency, scalability, and immediate time-to-market advantages, it also raises significant security concerns, particularly in data security and privacy. Ensuring data confidentiality and implementing robust access control mechanisms are crucial to addressing these security challenges. Without resolving these issues, the future widespread adoption of cloud computing could be hindered. In this paper we have result show response time for RR, ESCE, TTL and TLB for overall response time and data center processing time
AI Ethics and Big Data Governance in FinTech Applications
Authors: Geetesh Sanodia
Published: September 2024

The integration of Artificial Intelligence (AI) and Big Data analytics in the financial technology (FinTech) sector presents both significant opportunities and ethical challenges. This paper explores the core principles associated with the ethical use of AI and Big Data in FinTech, emphasizing concerns such as data privacy, algorithmic fairness, transparency, and governance. By examining case studies and analyzing industry practices, this study highlights the impact of these ethical considerations on consumer trust, regulatory compliance, and the overall efficacy of AI and Big Data applications in finance. Recommendations are provided to promote responsible use of these technologies in FinTech, ensuring fairness and integrity in their deployment.
Kearifan Lokal Sasi Terhadap Eksistensi Teripang di Desa Lelingluan, Kecamatan Tanimbar Utara, Kabupaten Kepulauan Tanimbar
Authors: Kormasela Dince Avia , Nifanngelyau Jakobus , Srue Olivir
Published: September 2024

Sasi is one of the indigenous wisdoms that have been preserved in the Tanimbar Archipelago Regency, North Tanimbar District, and particularly in Lelingluan Village. The Lelingluan village community is rich in culture and local wisdom, namely Sasi local wisdom. The local wisdom, or sasi, is usually used to conserve, maintain, and protect natural resources, both on land and at sea, with the aim that all communities can enjoy the results together. Sasi, which is usually done in general and involves traditional leaders and their  implementation through customary law procedures, is for sea cucumbers. This is because sea cucumbers are one of the marine resources that can meet the needs of the Lelingluan village community, so their existence must be maintained properly. Sea cucumbers, on the other hand, are one of Lelingluan village's properties; hence, sea cucumber sasi is included in the state sasi and must go through customary (oath) implementation before proceeding with ecclesiastical procedures. The existence of sea cucumbers in Lelingluan village can be preserved thanks to the local wisdom of sasi. This research aimed to describe the local wisdom in this case sasi, regarding the existence of sea cucumbers in Lelingluan village, North Tanimbar District, and Tanimbar Archipelago Regency.
Kristologi Humanis dan Diskriminatif bagi Etnis Tionghoa
Authors: Patty Martha Marselina
Published: September 2024

Racial discrimination generally arises from the perceived superiority of one particular ethnicity over other ethnicities. This is what happens to ethnic Chinese in Indonesia. Discrimination against ethnic Chinese is a phenomenon that has been going on for quite a long time. This can be seen from the cases of riots from 1998 to 2020, also when the Covid-19 pandemic hit the world which also hit Indonesia. This discrimination against ethnicity is carried out in verbal and physical form. This article aims to offer a humanist Christology of Jesus as a point of view on the problem of discrimination as stated above. The method used is library research which examines selected Christian texts and extracts and concludes them as a humanist attitude of Jesus. This research found that Jesus' good attitude towards people who were marginalized and looked down upon by other groups shows that Jesus began to build bridges for relations between humans regardless of ethnicity, religion,race and between groups. This research concludes that Jesus was very pro-humanity, He did not view other ethnicities as "non-natives" or small groups that should be isolated and ostracized, but as fellow humans who should be treated equally, even as brothers.
Musik Pop dan Kebebasan Berekspresi
Authors: Salenussa Peter Boris
Published: September 2024

All of artworks always give expression but not all expressions of artworks can be accepted by everyone. Rejection of certain artwork that is considered deviant, it means also resisting the expression of artwork. Music, especially pop music as part of the art often gets a lot of resistance because of the freedom of expression. In some cases denial of artistic expression in pop music in Indonesia, it is done based on norms that are considered to be noble social values.Without intending to assess which is the most correct, this paper will try to trace critically about what is behind the phenomenon of pop music that often reap the denial of freedom of expression. This article is not intended to reconcile the conflict between the many people who have refused the aberrant expression of music with product of pop music itself, but rather tries to lay the base of foundation that can be used by music, especially pop music, in the use of expression responsibly.
Pendidikan Seksual (Kesehatan Reproduksi & Personal Hygiene pada Masa Menstruasi) dan Pengukuran IMT pada Remaja
Authors: Andini Tressia , Brett Nito Paul Joae , Destriani Rizka Mariyana , Juniawinata Resa , Chaidir Shaila , Widia Widia , Yelika Yelika , Dano Rebecca Nathalie , Dhea Manto Onieqie Ayu
Published: September 2024

World Health Organization (WHO) tahun 2019 telah mensurvey dibeberapa negara dan menemukan banyak remaja putri usia 10-14 tahun mengalami gangguan kesehatan reproduksi, diantara masalah yang dialami adalah infeksi saluran reproduksi. Data statistik 2012 di Indonesia menunjukkan perilaku menstrual hygiene remaja pada level usia 10-14 tahun masih dalam kategori kurang baik. Maka dari itu, perlu dilakukannya pendidikan seksual untuk menumbuhkan kesadaran remaja putri akan pentingnya menstrual hygiene dan status gizi. Tujuan dari pendidikan kesehatan yang dilaksanakan adalah untuk meningkatkan pengetahuan remaja putri terkait menjaga asupan nutrisi, kesehatan reproduksi khususnya saat masa menstruasi. Metode yang digunakan dalam pendidikan kesehatan ini adalah metode ceramah, dan pengukuran IMT. Pengetahuan remaja putri meningkat setelah dilakukan pendidikan kesehatan mengenai cara Personal Hygiene yang benar, dan perawatan diri yang baik pada saat menstruasi.
Cenário das Práticas Administrativas em Acessibilidade e Internacionalização nas Universidades das Regiões Sul e Sudeste
Authors: Gehling Liska Milene , Barros de Sales Márcia
Published: September 2024

Este artigo objetiva mapear as práticas administrativas referentes à acessibilidade e à internacionalização, divulgadas nos sites das Instituições de Ensino Superior (IES) contempladas no edital CAPES-PrInt 2017. Trata-se de um estudo com abordagem qualitativa, caracterizando-se como descritiva e exploratória, que foi conduzido por meio de análise documental. A amostra intencional e não-probabilística compreendeu as dezesseis IES das regiões Sul e Sudeste do Brasil. Entre os resultados obtidos, em 14 IES da amostra, foram identificadas 52 práticas administrativas em acessibilidade, tais como: políticas, plano de ação, projetos de pesquisa, laboratórios de pesquisa e de tecnologias assistivas. Constatou-se, ainda, que, nos sites de 10 das 16 IES analisadas, não foram encontradas nenhum tipo de divulgação de práticas em Internacionalização.
The Rights of Minority Women Before the European Court of Human Rights: Critical Review in Light of the Practice of the UN Human rights comitee and other international human rights bodies
Authors:   European Court of Human Rights, Jelić Ivana
Published: September 2024

Women from ethnic, national, religious, and cultural minorities face distinct legal challenges in their struggle for gender equality. They are at constant risk of multiple discrimination as minority women, particularly with regard to their identity and religious rights. This is evident in matters of inheritance, wearing religious items in public, and issues related to sexual and domestic violence. International approaches to this problem are fragmented, with the ECtHR, UN HRC, and other international human rights bodies taking different approaches. This article will critically discuss the status of minority women’s rights in the jurisprudence of the ECtHR and will reflect on what the Court could learn from the practices of the UN HRC and other international human rights bodies.
Elements of Statehood of the Independent State of Croatia (1941–1945)
Authors:   University of Belgrade Faculty of Law, Serbia, Zdravković Miloš
Published: September 2024

The historical phenomenon of the Independent State of Croatia (NDH) is subjected to a basic legal theory analysis, which showed that this Nazi creation, at least to a minimal extent, possessed all the elements of statehood. On a large part of its territory, the Ustasha regime had a monopoly of physical force and was able to implement its basic political purposes. In this regard, the organization of terror against a large number of its inhabitants, which implied a completely new legislation, the formation of new judicial, police and other authorities, the organization of the camp system and railway transport, etc., proves a sufficient measure of the efficiency and regularity of the actions of the NDH state government. Such action produced wartime chaos, which eventually resulted in the loss of elements of statehood, with the creation of a new Yugoslav state in its territory.
Kontrola odluke o izboru na sudijsku funkciju u postupku pred Ustavnim sudom
Authors:   University of Belgrade Faculty of Law, Serbia, Bodiroga Nikola
Published: September 2024

The paper explores the review of decisions on the election to judicial functions. The candidate may file an appeal on the decision on the election to the judicial function to the Constitutional Court within 15 days from the day of the publication of the decision in the Official Gazette of the Republic of Serbia, which excludes the right to submit a constitutional appeal. Appeal to the Constitutional Court suspends the enforcement of the decision, which means that the elected candidate cannot take office before the appeal is decided. The scope of the Constitutional Court review has been limited to proper execution of powers by the High Judicial Council, following procedure provided for in the Law on Judges and the quality of reasoning in decisions on the election to the judicial function. So far, all appeals submitted to the Constitutional Court have been dismissed as manifestly ill-founded.
Leveraging Generative AI for On-Demand Tutoring as a New Paradigm in Education
Authors: Leon Maikel
Published: September 2024

Traditional education often fails to provide personalized, immediate support to all students, leading to gaps in understanding and learning inequality. Generative Artificial Intelligence (GenAI) offers a scalable, cost-effective solution for on-demand tutoring, providing personalized, 24/7 support. This paper explores the application of GenAI as an on-demand tutoring system, addressing the critical need for personalized, immediate educational support. Using GenAI to create an on-demand tutoring system that offers personalized, real-time student support is vital to today’s academic needs. Crucial components of this approach include advanced natural language processing to understand and respond to student queries, machine learning algorithms to adapt to individual learning styles, and a scalable cloud-based infrastructure to ensure 24/7 availability. This approach’s expected scientific surplus value lies in its potential to significantly enhance educational outcomes by providing scalable, personalized learning experiences. This paper outlines a pathway for future research and development in this area, highlighting the potential of GenAI to revolutionize education and improve learning outcomes for all students.