bluuebunny/crossref_metadata_2025 huggingface dataset:
Pengaruh Model Guided Discovery Learning (GDL) Berbantuan Benda Konkret terhadap Kemampuan Menganalisis Siswa Kelas V pada Muatan IPA Tema 6
Authors: Yunita Irma , Bintartik Lilik , Sukamti Sukamti
Published: December 2022

Abstract: The purpose of this study is to determine the effect of the Guided Discovery Learning (GDL) model using concrete objects on the ability of fifth grade students to analyze the theme of Science 6. The research uses a quasi-experimental design with a non-equivalent control group. The research sample included 26 students from the experimental class VB SDN Wlingi 02 and 25 students from the control class VA. Purposive sampling was used to collect samples. The test method was used to collect data. A multiple choice test was used as the instrument. Descriptive and inferential statistics were used to analyze the data. The results showed that the average experimental class outperformed the control class by 8.54 points. The paired t-test results obtained a significance value of .000 less than 0.05, indicating that the GDL model assisted by concrete objects has a significant influence on the ability of class V students to analyze the Science content of Theme 6. The results of the independent t-test show that there is no significant difference between the experimental class taught by the GDL model and the control class taught by the CTL model.

Abstrak: Penelitian ini bertujuan untuk mengetahui pengaruh model Guided Discovery Learning (GDL) berbantuan benda konkret terhadap kemampuan menganalisis siswa kelas V pada muatan IPA Tema 6. Penelitian menggunakan metode kuasi eksperimen dengan rancangan non-quivalent control group design. Sampel penelitian berjumlah 26 siswa kelas VB SDN Wlingi 02 sebagai kelas eksperimen dan 25 siswa kelas VA sebagai kelas kontrol. Sampel diambil menggunakan teknik purposive sampling. Data dikumpulkan dengan metode tes. Instrumen yang digunakan berupa tes pilihan ganda. Data dianalisis menggunakan statistik deskriptif dan inferensial. Hasil penelitian menunjukkan bahwa rata-rata kelas eksperimen lebih unggul 8,54 dari kelas kontrol. Hasil uji-t berpasangan memperoleh nilai signifikansi 0,000 kurang dari 0,05 yang berarti model GDL berbantuan benda konkret memiliki pengaruh yang bermakna terhadap kemampuan menganalisis siswa kelas V pada muatan IPA Tema 6. Hasil uji-t independen menunjukkan bahwa tidak terdapat perbedaan yang signifikan antara kelas eksperimen yang dibelajarkan dengan model GDL dan kelas kontrol yang dibelajarkan dengan model CTL.
Analisis Penerapan TPACK dalam Rencana Pelaksanaan Pembelajaran di Sekolah Dasar Negeri
Authors: Wardani Alifya Kusuma , Suhartono Suhartono , Rini Titis Angga
Published: December 2022

Abstract: TPACK is a framework that integrates three main areas of knowledge, namely technological knowledge, pedagogical knowledge, and content knowledge. These three knowledge are important knowledge and are in accordance with current educational needs. Therefore, it is important for teachers to be able to apply the TPACK framework in their lesson plans. The purpose of this study was to analyze the application of TPACK in the implementation plan of learning at SDN 01 Ngadilangkung, Kepanjen District, Malang Regency. This research is a mixed methods research / mixed methods research type explanatory sequential. Techniques in data collection using documentation, questionnaires and interviews. The validity of the data in this study used triangulation with this type of triangulation technique. Based on the research that has been done, the results show that the implementation of TPACK in the learning implementation plan at SDN 01 Ngadilangkung is included in good criteria with an average score of 77.5 percent.

Abstrak: TPACK merupakan kerangka yang mengintegrasikan tiga pengetahuan utama yakni pengetahuan teknologi, pengetahuan pedagogi, dan pengetahuan konten. Ketiga pengetahuan itu merupakan pengetahuan yang penting dan sesuai dengan kebutuhan pendidikan saat ini. Oleh sebab itu, penting untuk guru dapat menerapkan kerangka kerja TPACK dalam rencana pelaksanaan pembelajaran. Tujuan dari penelitian ini untuk menganalisis penerapan TPACK dalam rencana pelaksanaan pembelajaran di SDN 01 Ngadilangkung Kecamatan Kepanjen Kabupaten Malang. Penelitian ini merupakan penelitian mixed methods/ penelitian metode campuran jenis explanatory sequential. Teknik dalam pengumpulan data menggunakan dokumentasi, angket dan wawancara. Keabsahan data dalam penelitian ini menggunakan triangulasi dengan jenis triangulasi teknik. Berdasarkan penelitian yang sudah dilakukan, diperoleh hasil yang menunjukkan bahwa penerapan TPACK dalam rencana pelaksanaan pembelajaran di SDN 01 Ngadilangkung termasuk dalam kriteria baik dengan skor rata-rata sebesar 77,5 persen.
Pengembangan LKPD Berbasis Situation Based Learning Muatan Matematika Materi Bangun Ruang Kelas VI
Authors: Kumala Shukma Dyah Ayu , Yuniawatika Yuniawatika , Untari Esti
Published: December 2022

Abstract: Research and development of Situation Based Learning LKPD is conducted to improve the quality of learning and meaningful learning for students in the material of building class VI. LKPD Based on Situation Based Learning is a sheet of activity that contains material and assignments for students with 4 stages including creating mathematical situations, posing mathematical problem, solving mathematical problems, and applying mathematics. In this study using the ADDIE research model with 5 stages, namely Analysis-Design-Develop-Implement Evaluate). Data collection in this study was in the form of a questionnaire (questionnaire) which was given to the validation of material experts, media experts, and class VI teachers as users in the form of quantitative and qualitative data. The results of the validation by material experts showed a percentage of 95 percent, 100 percent of media experts, 93.75 percent of users and 96.9 percent of student response questionnaires, so it can be said that Situation Based Learning LKPD is very valid, practical and usable.

Abstrak: Penelitian dan pengembangan LKPD Berbasis Situation Based Learning dilakukan untuk meningkatkan kualitas pembelajaran dan pembelajaran bermakna bagi siswa pada materi bangun ruang kelas VI. LKPD Berbasis Situation Based Learning adalah lembaran aktivitas yang berisi materi dan tugas untuk siswa dengan 4 tahapan meliputi creating mathematical situation, posing mathematical probel, solving mathematical problem, dan applying mathematics. Dalam penelitian ini menggunakan model penelitian ADDIE dengan 5 tahapan yaitu Analysis-Design-Develop-Implement Evaluate). Pengumpulan data dalam penelitian ini berupa angket (kuesioner) yang diberikan kepada validasi ahli materi, ahli media, dan guru kelas VI sebagai pengguna berupa data kuantitatif dan kualitatif. Hasil validasi oleh ahli materi menunjukkan presentase sebesar 95 persen, ahli media sebesar 100 persen, pengguna sebesar 93,75 persen dan angket respon siswa sebesar 96,9 persen, sehingga dapat dikatakan bahwa LKPD Berbasis Situation Based Learning sangat valid, praktis dan dapat digunakan.
Ameloblastoma: A hostile lesion of mandible: A challenging case report
Authors: Sunil M. K. , Malik Upender , Vishnoi Lakshay , Srivastava Chhavi , Singh Priya
Published: December 2022

Swellings in the maxillofacial region always play a challenging task for clinicians to reach for apt diagnosis. These swellings can be soft, firm or bony hard in consistency. There are various clinical and radiographic features which are peculiar to these pathologies but sometimes the features are similar to more than one lesion. Thus, histopathological evaluation is must before planning for treatment. In this article we have discussed a case of swelling on the left side of face along-with the clinical, radiographical and pathological findings.
Craniofacial fibrous dyplasia: A case report with emphasis on radiographic findings
Authors: Durugkar Mrunmayee Shrikant , Patait Mahendra Ramdas , Saraf Kedar , Mulla Misbah Farheen , Tupsakhare Suyog , Jadhav Swati
Published: December 2022

Fibrous dysplasia (FD) is an idiopathic skeletal disorder where normal bone gets replaced by poorly organized fibrous connective tissue. The lesion is classified into two forms: monostotic and polyostotic. This disorder arises from sporadic mutation of the α-subunit of the Gs stimulatory protein. Although histopathology is a gold standard in the diagnosis of any pathology, radiology remains an important investigation. In radiology, fibrous dysplasia is very often associated with the term ground glass matrix. The knowledge of its unique pathogenesis and course are crucial to understand imaging findings and potential complications. Here, we are presenting case report of fibrous dysplasia involving the craniofacial bones.
Demethylase FTO promotes neuropathic pain development via regulating the m6A methylation levels of CXCR3
Authors: Wu Song Fei , Wang Yang , Zhao Qiu Cheng
Published: December 2022

Objective: Neuropathic pain (NPP) is an indirect or direct pain caused by somatic sensory nervous system dysfunction or primary injury, which is considered to be one of the most serious public health problems. This study aimed to investigate the role of adiposity-associated protein (FTO) in NPP. Materials and Methods: Sciatic nerve injury (SNI) treatment was performed to establish an NPP model in vivo. The qRT-PCR and western blot assays were conducted to measure the relative mRNA and protein expressions. Additionally, the paw withdrawal threshold (PWT) and paw withdrawal latency (PWL) of the mice were measured on days 0, 1, 3, 5, 7, and 14. The m6A level of CXCR3 was determined with Methylated RNA immunoprecipitation (MeRIP) assay and the inflammatory factor expressions were determined with Elisa kits. Results and Discussion: The FTO and CXCR3 expressions were up-regulated and the METTL14 expression was down-regulated in SNI mice. FTO-silenced increased the m6A and decreased the mRNA levels of CXCR3 in SNI mice. Furthermore, FTO-silenced decreased the mRNA stability of the CXCR3. Besides, in the SNI mice, FTO-silenced increased the PWL and PWT, and decreased the TNF-α, IL-1β, and IL-6 levels. While over-expressed CXCR3 inverted the FTO-silenced effects. Conclusions: Knockdown of FTO relieved the NPP progression via triggering the demethylation of CXCR3, thereby down-regulating the CXCR3expression.
Białka z rodziny Bcl-2 oraz neurotrofiny jako istotny czynnik decydujący o przeżywalności neuronów obwodowych u zwierząt transgenicznych
Authors: Trzęsicki Michał , Białoń Natalia , Kuźma Damian , Górka Dariusz
Published: December 2022

Apoptoza jest uporządkowanym, czynnym procesem przebiegającym z aktywacją określonych genów, w wyniku którego komórka może wejść na drogę programowanej śmierci. Podczas embriogenezy, zaprogramowane szablony śmierci komórkowej w regresji struktur pierwotnych lub nieprawidłowych są niezbędne w prawidłowym kształtowaniu narządów i funkcjonowaniu układu nerwowego. Z kolei, nasilona śmiertelność komórek w dojrzałym układzie nerwowym może prowadzić do różnych chorób neurodegeneracyjnych. Z tych powodów rodzina białek Bcl‑2 jest intensywnie badana w kontekście funkcjonowania układu nerwowego. Programowana śmierć komórki (PCD) pozwala eliminować komórki zbędne, przyczyniając się w ten sposób do utrzymania homeostazy w organizmie. Jako przykład można podać usuwanie z tkanek komórek starych, uszkodzonych lub nadliczbowych. Nieprawidłowa regulacja apoptozy charakterystyczna jest dla procesów nowotworowych, zmian zwyrodnieniowych i schorzeń autoimmunologicznych. Obecnie badania nad ekspresją genów białek pro- i antyapoptotycznych, z zastosowaniem technologii knock‑out budzą wielkie nadzieje na leczenie pacjentów, dotkniętych zmianami neurodegeneracyjnymi. Aktualne odkrycia sugerują, że nie bez znaczenia pozostaje stosunek poziomów ekspresji genów białek Bcl‑2 i Bax. Białka Bcl‑2 poprzez regulację kaspazo- zależnej apoptozy w neuronach, zapobiegają szybkiej degeneracji wallerowskiej. Możliwości oddziaływania absencji genu bcl-2 na substancje i czynniki neurotroficzne może mieć przełożenie na proces regeneracji nerwów obwodowych.
Mózgowy metabolizm glukozy i wybranych jej transporterów w chorobach neurodegeneracyjnych.
Authors: Białoń Natalia , Trzęsicki Michał , Górka Mikołaj , Suszyński Krzysztof , Górka Dariusz
Published: December 2022

Mózgowy metabolizm glukozy jest zagadnieniem, które w dalszym ciągu stanowi przedmiot zainteresowań naukowców. Zaburzenie transportu i metabolizmu glukozy w mózgu może być czynnikiem rozwoju licznych patologii. Wyniki badań ostatnich lat wykazują istotny związek pomiędzy zaburzeniami mózgowego metabolizmu glukozy a rozwojem chorób neurodegeneracyjnych. Glukoza jest monosacharydem stanowiącym główne źródło energii komórek mózgu. Mózg jest organem najbardziej wrażliwym na zmiany stężenia glukozy we krwi. Zaburzenia w transporcie glukozy doprowadzają do powstania zmian w obrębie ośrodkowego układu nerwowego. Choroby neurodegeneracyjne w literaturze definiowane są jako postępujące i nieodwracalne zwyrodnienia tkanki nerwowej, której komórki obumierają w wyniku procesów degeneracyjnych. Celem niniejszej pracy jest opisanie fizjologii i roli wybranych transporterów glukozy oraz przedstawienie ich znaczenia w rozwoju chorób neurodegeneracyjnych. Omówiono tutaj zaburzenia ekspresji wybranych transporterów: GLUT1 oraz GLUT3 w chorobie Alzheimera i Pląsawicy Huntingtona. Zrozumienie podstaw mózgowego metabolizmu glukozy może stanowić istotny czynnik w walce z chorobami w obrębie ośrodkowego układu nerwowego.
Histon H1 – struktura i funkcja
Authors: Kilichowska Marta , Kotliński Maciej
Published: December 2022

Histony łącznikowe (H1) są białkami występującymi w jądrze komórkowym większości eukariontów. Pełnią ważną rolę w ich życiu i rozwoju, uczestnicząc m.in. w kondensacji chromatyny, regulacji transkrypcji genów czy indukcji apoptozy. Mimo powszechnego występowania oraz istotnych funkcji H1, na wiele pytań nie znaleziono dotąd odpowiedzi. Zagadką pozostaje mechanizm odpowiedzialny za tryb wiązania tego histonu do nukleosomu oraz wpływ każdego z trybów na strukturę chromatyny. Pojawiają się również doniesienia na temat uczestnictwa H1 w procesach fizjologicznych nie związanych bezpośrednio z organizacją materiału genetycznego. Postuluje się, że histon ten bierze udział w powstawaniu wrzeciona podziałowego u roślin, a jego fragmenty – w obronie ryb przed patogenami. Artykuł ten ma na celu przyjrzenie się histonowi H1 pod wieloma aspektami, zgromadzenie i uporządkowanie zdobytej już wiedzy oraz nakreślenie pytań, na które odpowiedzi należy szukać w przyszłości.
The works of А. N. Radishchev: A study of economic and anthropological interpretation
Authors:   Saratov State University, Maximov Vadim A.
Published: December 2022

Introduction. A. N. Radishchev in his writings lays the foundations of a humanistic study of Russian society and an anthropological understanding of economic orders. Most of the works were not published during his lifetime; the scientific publication of works and the study of views, mainly of a social nature, was undertaken in the 1940s–1950s. The comments emphasized the radical worldview of the thinker, manifested in the literary field. In reality, the enlightener’s work is more multifaceted and covers philosophy, law, history, and economics. Three life periods are distinguished, different in subject matter, but consonant with moral ideas. Theoretical analysis. The first period of writing is characterized by works of social philosophy, fiction and official notes of a legal and economic nature, in which Radishchev’s ambivalent attitude to power, lawmaking and moral values is revealed. The probable coincidence of the enlightener’s views with his European contemporaries (Locke, Diderot, A. Smith, Blackstone) and Russian philosophers (Tatishchev, Storkh) is revealed. Parallels with the works of I. Kant and the categorical apparatus of modern economic anthropology are determined. Empirical analysis. The views of Radishchev and Catherine II are interpreted in a comparative way. It is shown that there are no direct invectives in the “Journey from St. Petersburg to Moscow” against the Empress. The works on legislation in the third period of creativity are an adjusted continuation of the works of the first period. The most complete economic and anthropological theme is presented in the essay “On Chinese Bargaining”, which implicitly rejects the principles of the government’s economic policy, which does not take into account the spatial identity of Russia, its civilizational mission and the potential of free enterprise. Results. The writings of A. N. Radishchev anticipate the field of research of modern economic anthropology: the importance of reflection in human behavior, its noumenal and phenomenal representation, historical construction of ways of action and thought, performative thinking, hierarchy and fragmentation of power, structuration of economic (market) relations are taken into consideration. The key concepts are collective faith, feelings and habits, inclinations and individual differences, good-action, objective and subjective interests, reasonableness and rationality in historical refraction. The problems of conciliarity, will, moral imperatives, acquisition of systematic knowledge, necessity of laws, human rights are highlighted as the most important from the position of the enlightener.
Forming a model for assessing economic security in conditions of digital transformations
Authors:   Yuri Gagarin State Technical University of Saratov, Levchenko Ekaterina V. , Levchenko Andrey A. ,   Stolypin Volga Region Institute of Administration of the Russian Presidential Academy of National Economy and Public Administration
Published: December 2022

Introduction. New economic conditions today are reflected in the development of the digital economy and determine the need to develop new methods of assessment, management, ways to attract specialists. In this article, an attempt was made to formulate a model for assessing economic security in the context of digital transformation, showing how the introduction of digital technologies contributes to the growth of real industry indicators and indicators and economic security. Theoretical analysis is based on the assumption that the effectiveness of digital transformations is expressed through the rate of change in the economic security indicators of a particular industry. For example, the agro-industrial complex was chosen as the key one in the field of maintaining the food and economic security of Russia. The model for assessing the economic security of innovation activity includes four stages: the formation of a set of indicators that characterize the level of digital development of the industry; construction of a reference series and ranking of indicators; comparison of the actual ranking series with the reference ranking series, calculation of the development coefficient; interpretation of the digital transformations’ economic security assessment results. Empirical analysis. The results obtained indicate that there are pathological problems in the industry that cannot be resolved through digitalization, this is proved by the development coefficient trend: there is an outstripping growth of investment in digital development against the backdrop of weakly growing intra-industry indicators; there is a decrease in the real disposable income of the population against the backdrop of rising inflation, which affects the purchasing power of the population; in the agro-industrial complex there is a high level of depreciation of fixed assets. Conclusions. The use of the economic security assessment model quite informatively reflects the current realities of economic development. The results of the assessment showed the presence of crisis phenomena in the industry and its grave condition. A way of solving the existing problems can be the increase of economic security both at the level of the state and industry, and at the level of a single organization.
Conceptual approach to the classification and certification of robots and complex automated information systems
Authors:   Saratov State University, Amelin Roman V. , Bessonov Leonid V. ,   Saratov State University, Komkova Galina N. ,   Saratov State University, Channov Sergey E. ,   Saratov State University, Stolypin Volga Region Institute of Administration of the Russian Presidential Academy of National Economy and Public Administration
Published: December 2022

Introduction. The development and spread of robots, artificial intelligence systems and complex automated information systems are associated with the problem of causing harm by their decisions and actions, as well as the problem of legal liability for this harm. Theoretical analysis. One of the main functions of legal liability is general and private prevention. When applied to robots, it requires them to be reprogrammed, retrained, or eliminated. Thus, the issue of the possibility, forms and conditions of their existence is directly related to the problem of legal responsibility of autonomous and sometimes unpredictable software and hardware mechanisms. A systemic legal structure aimed at ensuring safety and predictability in the creation and operation of robots can be built on the basis of a classifying standard, and each class will be associated with certain forms and models of responsibility. Empirical analysis. The basis of the legal classification of robots and complex automated information systems will be the threats associated with causing harm as a result of their spontaneous actions and decisions, correlated with the forms of legal liability. The following threats can be identified: causing the death of a person; unlawful change in the legal status of the subject; causing material harm; violation of the personal non-property rights of a person; information or other property of the owner (user), not related to causing harm to third parties; the threat of illegal behavior of robots. Results. The authors propose a classification of robots and complex automated systems, as well as approaches to legal liability and security for each class, and indicate directions for promising development of legal and technical standards necessary to ensure this classification and certification.
Interruption des enseignements par les « congés anticipés » et violence en milieu scolaire en Côte d’Ivoire : Causes, manifestations, meneurs et mécanismes de gestion
Authors: Hillarion BENIE Aloh , Adigra MESMIN Ehui
Published: December 2022

Violence persists more and more in schools, particularly in Côte d'Ivoire, where it is experiencing a resurgence through early leave which consists of the cessation of classes in secondary schools. She intervenes under the pretext of wanting to go on Christmas leave before the date officially prescribed by the educational authorities. The recurrence of the phenomenon with its share of destruction of material goods and loss of human life prompted this study. Its objective is to analyze the manifestations of early leave in order to propose management mechanisms. The data was collected in the municipalities of Cocody and Yopougon, the epicenter of the phenomenon, from students, teachers and educators. A questionnaire and an interview guide were used for data collection. The results indicate that the main causes are group spirit, the expression of bravery and the reproduction of violent behavior among students. The warning signs are hissing and dislodging of classes by throwing stones. The leaders are students, generally from the second cycle and male. The mechanisms for managing early leave proposed by the respondents focus more on preventive measures.
Use of Stream of Consciousness in Brick Lane: A Psychoanalytical Approach to Study Nazneen’s Evolution
Authors: Jabin Haque Manfath
Published: December 2022

This paper attempts an interpretive study of Monica Ali’s use of steam of consciousness in her first novel Brick Lane (2003), examining the psychological connection with this technique to comprehend the protagonist Nazneen’s evolutionary expedition. Brick Lane starts with the stillbirth of Nazneen and by her mother’s influence she learns to accept fate without any question. After her marriage with Chanu, she becomes a British immigrant and embarks her journey to adjust in a new place, new life and to form a new identity beyond the patriarchal constraints. Throughout the novel, she undergoes various internal and external dilemma and troubles; but, she establishes her own identity by attaining economic emancipation and by establishing her logical opinion. This paper purports to interpret step by step journey of ‘a village girl’ Nazneen towards her transformation as an independent woman retaining her native cultural values. The study identifies the stream of consciousness used by the author to reveal the mind’s workings of Nazneen behind her behaviours and activities. This article attempts to explore the psychological interpretation of Nazneen’s thoughts and actions. In this regard, Freud’s theory of ‘unconscious’ and ‘conscious’ mind is used to explore how her stream of consciousness works for the readers to dive deep into the character to comprehend her predicament and upswing.  This paper presents, through a psychoanalytical approach, an in-depth textual interpretation of Nazneen’s story with a specific reference to her stream of consciousness.
Knowledge Creation and Performance of Private Health Facilities in Kisii County, Kenya
Authors: Manyange Abuki Alice , Muchemi Anne W.
Published: December 2022

Well performing private health facilities afford countries access to quality healthcare and support services, easing the disease burden in public health facilities. Being a knowledge-driven industry, the field of medicine keeps advancing, highlighted by new discoveries in treatments from continuing research. As such, desirable performance among private health facilities would ideally necessitate that healthcare providers adequately share knowledge. By so doing, when one that bears knowledge that is specialized exists the facility, other staffs may continue accessing the knowledge, thus decreasing the probability of committing errors as a result of misinformation. Whereas extant studies attempt to link knowledge sharing and organizational performance, their focus has been on industries other than private healthcare. The present research thus set out to assess the effect of knowledge sharing on the performance of private health facilities in Kisii County, Kenya. The study was grounded on both knowledge-based view, and upper echelon theories. The research adopted both descriptive and explanatory research designs, with the target population comprising 135 staff drawn from all 43 private health entities in Kisii County. The research used a census survey with one top cadre staff from each facility forming the unit of observation. The research involved the gathering of data that is primary by utilizing a questionnaire that is semi-structured. Inferential and descriptive calculations were then computed in data analysis. Findings reveal a statistically significant relationship between knowledge sharing (β = .221, Sig.=.008<.05) and performance. It is thus concluded that knowledge sharing significantly influences performance among private health facilities in Kisii County, Kenya. The study recommends that in order to realize improved and superior performance, private health facilities in the country ought to invest in knowledge sharing.
Papiller Tiroid Kanserli Hastalarda Preoperatif Santral Lenf Nodu Metastazının Öngörücüsü Olarak Glikoz-Lenfosit Oranı
Authors: ALKURT Ertugrul Gazi , TURHAN Semin , ŞAHİN Fatih , TUTAN Mehmet Berksun
Published: December 2022

Amaç Papillertiroid kanserinde santral lenf nodlarının metastazının cerrahi öncesi saptanması zordur. Papiller tiroid kanserinin tedavisinde santral lenf nodu diseksiyonunun rolü belirsizliğini koruyor. Bu çalışma, papiller tiroid kanserli hastalarda preoperatif santral lenf nodu metastazı oluşumunu öngörmek için hazır preoperatif klinik özelliklere dayalı bir nomogram oluşturmayı amaçladı Gereç ve Yöntemler 2013-2022 tarihleri arasında bilateral total tiroidektomi yapılmış papillertiroid karsinomu tanılı hastalar tarandı ve 314 hasta çalışmaya dahil edildi. Hastaların demografik verileri, operasyon süresi, TSH, T3, T4 düzeyleri, glukoz/lenfosit oranları (GLR), patoloji raporlarındaki lenfovasküler invazyon, kapsül invazyonu ve boyun metastazı durumu retrospektif olarak taranarak not edildi. Tüm istatistiksel analizler için IBM SPSS 26.0 kullanılarak değerlendirildi. p
Long-Term Consequences Of Intensive Care Patients Diagnosed With COVID-19 Infection After Hospital Discharge
Authors: GÜLTEKİN Yücel , ÖZÇELİK Zerrin
Published: December 2022

Introduction: The Covid 19 pandemic has become a serious health problem that spreads rapidly in the world and in our country. The problems that may be encountered in the future in patients with Covid-19 infection are still unknown. This study aimed to evaluate long-term symptoms following Covid-19 infection. Materials and Methods:This study evaluated post-discharge continued symptoms of patients hospitalized in the intensive care unit with the diagnosis of Covid-19. Results: The most common symptom that persisted after Covid-19 infection was fatigue. It was determined that as the age of the patient increases, the incidence of symptoms after Covid-19 infection increases. Conclusion: There are persistent symptoms after Covid-19 infection. Their identification is crucial for early diagnosis and treatment.
Mędrzec zawsze niesie ludziom ocalenie - poza granicami wyobraźni: rozważania nad humanistycznym przekazem "Księżniczki Mononoke" jako filmowym centrum twórczości Hayao Miyazakiego
Authors: Braszka Justyna
Published: December 2022

Celem artykułu jest przedstawienie różnych perspektyw filmu Księżniczka Mononoke — dzieła anime autorstwa japońskiego reżysera Hayao Miyazakiego, które jest zdominowane przez motywy ekologiczne i myśl antropocentryczną. Artykuł przedstawia humanistyczną perspektywę filmu, która koresponduje z innymi obrazami japońskiego twórcy. Tekst obejmuję analizę filmoznawczą i przedstawia perspektywę antropologiczną (w tym byty nieludzkie wywodzące się z japońskiego folkloru) oraz motywy historyczno-społeczne, do których należy krytyka współczesnego społeczeństwa i wpływy myśli postkolonialnej. Dodatkowo filmy Miyazakiego zostały zilustrowane pod kątem filozofii taoistycznej.
Field Efficacy of Cowpathy Products and Biological Control Agents in Controlling Banded Leaf and Sheath Blight Disease and Increasing Maize Yield
Authors: Yadav Lokesh , Kumar Ashwani , Punia Rakesh , Yadav Naresh Kumar , Yadav Pankaj
Published: December 2022

Background: Maize is an important cereal crops as it is a good source of nutrition and raw material for industries. Among various pathogens attacking maize crop, banded leaf and sheath blight (BLSB) caused by Rhizoctonia solani f.sp sasakii is a potential threat for quality maize production. It affects all the plant parts at every stage of crop growth. Methods: The present investigation was carried out at Regional Research Station Uchani, Karnal of CCS Haryana Agricultural University, Hisar to evaluate the efficiency and efficacy of biorational products (Cowpathy) such as Vedic Krishi inputs viz., Beejamrit and Jiwamrit, compost extract and biocontrol agents with the objective to manage banded leaf and sheath disease and increasing yield of maize. Result: All the biorational products were found quite effective in controlling the disease and enhancing the yield attributes. Seed treatment with Achook (Neem based fungicide containing azadirachtin) @ 2 g/l of seed was found most effective in controlling disease upto 51.77 per cent. Seed treatment with Pseudomonas fluorescens @ 10 ml/kg followed by Beejamrit @ 10 ml/kg were also found effective in reducing the disease incidence as compared to control. These are economic, reliable and viable sources and hold good promise for use in organic and sustainable agriculture.
Local Girth Choosability of Planar Graphs
Authors: Postle Luke , Smith-Roberge Evelyne
Published: December 2022

In 1994, Thomassen famously proved that every planar graph is 5-choosable,
resolving a conjecture initially posed by Vizing and, independently, Erd˝os, Rubin, and Taylor in the 1970s. Later, Thomassen proved that every planar graph of girth at least five is 3-choosable. In this paper, we introduce the concept of a local girth list assignment: a list assignment wherein the list size of a vertex depends not on the girth of the graph, but rather on the length of the shortest cycle in which the vertex is contained. We give a local list colouring theorem unifying the two theorems of Thomassen mentioned above. In particular, we show that if G is a planar graph and L is a list assignment for G such that |L(v)| ≥ 3 for all v ∈ V(G); |L(v)| ≥ 4 for every vertex v contained in a 4-cycle; and |L(v)| ≥ 5 for every v contained in a triangle, then G admits an L-colouring.
Medico-Legal Examination of Sexual Assaulted Victims Unable to Consent in Portugal: Ethical Decision-Making
Authors: Santa-Rosa Bárbara , Silvestre Margarida , Vieira Duarte Nuno , Corte Real Francisco
Published: December 2022

Medical decision-making is a complex task in any field. In the medico-legal examination of victims that have (allegedly) been sexually assaulted there are many specific variables and features influencing the decision. It is essential to complement the clinical intervention with a forensic approach. Clinical parameters such as the victim’s physical and cognitive state along with circumstantial information such as the elapsed time from the event and the type of abuse (described or suspected) grant different levels of priority to the forensic medical assessment. In such cases, forensic medical doctors or other medical doctors responsible for attending to the victim may have to decide whether to perform the examination prior to a judicial analysis of the case if consent cannot be obtained. This implies the need to deliberate about performing the examination and/or reporting the case to legal authorities. This article discusses the forensic medical decision-making process in cases of alleged recent sexual assault of victims who are legally unable to consent or unable to consent for other reasons. We aimed to identify possible ethical problems that can arise in this context and discuss which elements should be considered by medical doctors when making decisions about such cases. The Portuguese legal framework of medico-legal examinations is analyzed. The authors also make considerations about reporting these cases from a legal point of view. The discussion turns to an ethical perspective where possible ethical problems arising from medical deliberation are identified. Issues about legally incompetent victims and incompetent victims due to other reasons are addressed. A decision-making tree, based on the problems identified, is proposed.
Nature of Literacy Instruction in Elementary School History Lessons
Authors: Khawaja Amna , Puustinen Mikko
Published: December 2022

This paper examines literacy-related practices existing in elementary history classrooms and asks to what extent these practices are compatible with the ideals of historical literacy, i.e. disciplinary literacy specific to history. A total of 50 hours were spent observing nine Finnish classrooms. Data sources included numeric data, field notes and classroom artifacts. The results show that the most common text type used was the body text of a textbook while primary sources were few. The textbook was typically addressed as a neutral source of information. Teachers used visual texts only briefly and to support an existing narrative. None of the teachers modeled reading strategies specific to history. The teacher profiles suggest diverse approaches to literacy but the practices used by teachers point more to content-area and cultural literacy than disciplinary literacy. Implications for elementary literacy and history instruction are discussed.
Analysis of the Differences between Employees Perceptions of Remote Working According to Demographic Characteristics
Authors: Toygur Eroglu Duygu , Gundem Ramazan , Eroglu Umut
Published: December 2022

Uzaktan çalışma, gündeme geldiği 1970’li yıllardan, Covid-19 pandemisinin yaşandığı döneme kadar nispeten daha yavaş bir gelişim gösterse de pandeminin yaratmış olduğu olağanüstü koşullar nedeniyle zorunlu bir çalışma biçimine dönüşmüştür. Uzaktan çalışmanın pandemi ile yaygınlaşan bir olgu alarak öne çıkması, örgütler, çalışanlar, toplum ve çevre açısından sağladığı olası faydalarını daha çok görünür hale getirmiştir. Aynı zamanda, uzaktan çalışma uygulamalarında karşılaşılan güçlükler hem araştırmacılar hem de uygulamacıların dikkatini bu yöne çekmiştir. Bu çalışma, işletmelerde uzaktan çalışanların, uzaktan çalışma deneyimlerine yönelik algılarının, demografik özelliklerine göre farklılaşıp farklılaşmadığını ortaya koymayı amaçlamaktadır. Uzaktan çalışma deneyimine sahip 667 kişiden, anket tekniği kullanarak veri toplanmıştır. Veriler, t-testi ve tek yönlü varyans analizi (ANOVA) kullanılarak analiz edilmiştir. Çalışmanın bulguları, belirlenen demografik değişkenlere göre çalışanların genel uzaktan çalışma algıları arasında istatiksel olarak anlamlı bir farklılık olmadığını göstermektedir. Buna karşın, uzaktan çalışma algısı ölçeğinin uygunluk, toplum üzerindeki etki, organizasyonel destek, ilişkilerin etkilenmesi, iş-yaşam dengesi, finansal katkı ve beceri gelişimi algısı boyutlarında demografik değişkenlere göre anlamlı farklılıkların olduğu tespit edilmiştir.
Implementation of Corporate Social Responsibility (Compatibility of The Programme with Smes Needs, Smes Capabilities, and Organisations Capabilities)
Authors: Chotimah Nur
Published: December 2022

Corporate Social Responsibility (CSR) emerges as a concept that requires companies not only focus on business profit, or to meet the demands of company shareholders, but also to fulfill the interests of all stakeholders. In Indonesia, implementation of CSR has been regulated by Law Number 40 of 2007 concerning Limited Liability Companies, Article 74, even for State-Owned Enterprises (BUMN). PT. Telkom Jatim as one of BUMN in Indonesia provides CSR to SMEs in Tanggulangin, Sidoarjo. This study aims to describe the compatibility of the CSR programme with SMEs needs, SMEs capabilities, and organisations capabilities of PT. Telkom Jatim for SMEs Tanggulangin, Sidoarjo. This research uses qualitative research methods through in-depth interviews, observation, and documentation. The conclusions obtained from this study are the compatibility of the CSR programme with SME needs, SMEs capabilities, and organisations capabilities to implement CSR of PT. Telkom Jatim in SMEs Tanggulangin, Sidoarjo is appropriate, although there are still things that need to be improved, so that the implementation of the CSR programme PT. Telkom Jatim can meet the expectations of SMEs players and provide positive feedback for the company.
MYOPIA PREVALENCE AMONG STUDENTS DURING COVID-19 PANDEMIC. A SYSTEMATIC REVIEW AND META-ANALYSIS
Authors: Savitri Natasha Hana , Adinda Sandya Poernomo  , Muhammad Bagus Fidiandra1  , Eka Candra Setyawan1  , Arinda Putri Auna Vanadia1  , Bulqis Inas Sakinah1  , Lilik Djuari
Published: December 2022

The lockdown policy was implemented during the Covid-19 pandemic to stop its spread. Indonesia modified the lockdown into PSBB (Pembatasan Sosial Berskala Besar). During PSBB school activities were replaced with online learning methods. This increased screen time and near-sighted activities and reduced time outdoors, were the risk factors for myopia. The objective of this study was to determine the myopia prevalence among students during the pandemic. This study used a systematic review method with meta-analysis. Data collection was taken from PubMed, Mendeley, and Google Scholar databases published in 2020-2021. The inclusion criterion was research on myopia prevalence among students during the pandemic of Covid-19. Data retrieval used the PICO method and journal adjustments were selected using the PRISMA algorithm. Data analysis was performed using a random-effects model. Out of 971 studies found, only six studies met the criterion. The results of the study based on the forest plot showed high heterogeneity and significant differences in the results. This was probably due to the inclusion criterion being too broad. In the funnel plot, there was a possible publication bias because the data obtained was only available and accessible. Overall, the journals studied stated that increased screen time and lack of outdoor activity increased myopia prevalence. Other risk factors that consistently cause an increase in myopia prevalence are education level, paternal and maternal myopia, and too-close reading distance. Otherwise, age, gender, BMI, eye exercise, eating habits, posture, and lighting while reading showed so many differences in the results that conclusions cannot be made.
COMMUNITY DEVELOPMENT INFLUENCE ON PUBLIC’S KNOWLEDGE IN MANDANGIN ISLAND ABOUT ACUTE DIARRHEA AND FUNCTIONAL CONSTIPATION IN CHILDREN
Authors: Ranuh Reza Gunadi , Susianto Steven Christian , Athiyyah Alpha Fardah , Darma Andy , Puspitasari Dwiyanti , Sumitro Khadijah Rizky , Nesa Ni Nyoman Metriani , Faizi Muhammad , Sudarmo Subijanto Marto
Published: December 2022

In children, acute diarrhea and functional constipation (FC) are still more prevalent in Indonesia, especially in isolated islands, and need comprehensive management. This study aimed to determine the effect of community development from the Department of Child Health Faculty of Medicine, Universitas Airlangga, Surabaya, on Mandangin Island’s public knowledge about acute diarrhea and functional constipation in children. This cross-sectional study was conducted on 29 subjects from Mandangin Island, Sampang, Indonesia on 17th February 2022. Subjects were given education and dissemination as community development by pediatricians via hybrid and could ask questions and discuss at the end of the presentation. The subject’s knowledge was measured using a pre-and post-test questionnaire about children’s acute diarrhea and functional constipation. Each questionnaire (diarrhea and functional constipation) consisted of 5 questions, with a minimum score of 0 and the maximum score of 100. The subject's knowledge was compared before and after the webinar using Paired T-Test and p<0,05 was measured as significant. We assessed the subject’s age, gender, occupation, and last education. There was a significant increase in public knowledge about diarrhea (26,9±18,7; 55,1±24,3; p=0.000) and functional constipation pre-and post-webinar (24,8±18,2; 48,3±24,2; p=0.000). These findings support the importance of community development with education about acute diarrhea and functional constipation in children.
A QUALITATIVE STUDY OF THE KNOWLEDGE OF INFORMAL CAREGIVERS OF CHILDREN WITH HIV/AIDS ON ANTIRETROVIRAL THERAPY ADHERENCE
Authors: Osman Wahab , Lilian Yiryuo  , Stephen Kpekura
Published: December 2022

The burden faced by informal caregivers in caring for a child diagnosed with HIV/AIDS, and placed on Antiretroviral Therapy (ART) is high due to the nature of the child’s dependence on the caregiver for fulfilling the child’s necessary needs. Evidence linking knowledge to the likelihood of performing the desired action exists. It is therefore crucial to explore caregivers’ knowledge of ART, and how that influences their children’s adherence to ART. The sought to explore the knowledge of informal caregivers on adherence to ART among their children with HIV/AIDS who received care at St. Joseph’s Hospital, Jirapa, Ghana. A qualitative phenomenology design was used. Data were collected from 13 purposively chosen caregivers of children with HIV/AIDS on ART at a hospital, using a semi-structured in-depth interview guide. A reflexive thematic analysis approach was used for data analysis. Informal caregivers were knowledgeable in the regularity of visits to the HIV Testing and Counselling (HTC) Centre for ARTs, identifying ARTs, ARTs administration, ARTs side effects identification, HIV transmission, and the nutritional restrictions for ARTs. A few, however, had misconceptions about HIV transmission. Informal caregivers still need education in the area of HIV transmission. The findings will guide nurses to focus on areas of education for informal caregivers to improve upon their knowledge of ART and to ensure increased adherence among children living with HIV/AIDS under their care.
Preliminary Phytochemical Studies, GC-MS Analysis, and Anti-Nephrototic Activity of Ethanol Extract of Phoenix dactylifera L
Authors: Warsinah Warsinah , Rachmani Eka Prasasti Nur , Diastuti Hartiwi
Published: December 2022

Date palm seeds (Phoenix dactylifera L.) are known to contain phenolic compounds that have the potential as natural nephroprotective agents. Phenolics with solvents suitable for polarity and compounds identified by phytochemical screening, GC-MS analysis, and activity assays. This research went through 3 stages, screening with exploration and qualitative analysis of GCMS. The anti-nephrotoxic activity test used a pre-posttest controlled group design. In this study, rats have divided into six groups, namely Healthy control, negative control, and three treatment groups with ethanol extract of dates 150, 300, and 600 mg/kg. Mice were induced with 1% carrageenan twice a week. On macroscopic observation, date palm seeds are oval with indentations and light brown with a hard texture. Microscopic profile, endosperm, parenchyma, endocarp, stone cells, collenchyma, starch, oil cells, and carrier bundles. Physicochemical analysis, water content (8%), ash content (1.15%), fiber content (14.96%), and ethanol soluble extract content (10.3%). GC-MS analysis showed phenol,2,6-bis(1,1-dimethyl ethyl)-4-methyl, 1,2-benzene dicarboxylic, and dihydromethyl jasmonate. A dose extract ethanol of 600 mg/kg BW reduces urea and creatinine levels up to 8,3 mg/dl and 0.132 mg/dl. The conclusion of the phytochemical study obtained a pharmacognostic profile. The GCMS analysis obtained the compound. The activity of the ethanol extract of date palm seeds can reduce urea and creatinine levels so that it developed as an anti-nephrotoxic alternative from natural ingredients.
Preparation of Atorvastatin Calcium-Dipicolinic Acid Multicomponent Solids by Liquid-Assisted Grinding Method to Increase Solubility
Authors: Wicaksono Yudi , Tsaniyah Shafira Faradiba , Wisudyaningsih Budipratiwi , Barikah Kuni Zu''aimah , Sari Lusia Oktora Ruma Kumala
Published: December 2022

Atorvastatin calcium is a cholesterol-lowering drug that is very potent but difficult to dissolve in water, so its bioavailability is low. In this study, atorvastatin calcium-dipicolinic acid multicomponent solids were prepared using the liquid-assisted grinding method to improve atorvastatin calcium's solubility. Characterization of multicomponent solids was carried out using powder x-ray diffraction (PXRD), differential scanning calorimetry (DSC), fourier transform infrared spectroscopy (FTIR), and scanning electron microscopy (SEM). Solubility test was carried out by shaking method using distilled water media. The results showed that the particles of atorvastatin calcium - dipicolinic acid multicomponent solids had an irregular shape with rough and porous surface topography. The multicomponent solids have a diffractogram with specific peaks of 2θ at 8.8, 9.9, 11.5, 16.7, 19.1, 21.2, 22.4, 23.4, and 27.7°. The DSC thermogram of multicomponent solids showed a sharp endothermic peak at 181.9 °C (∆H=17.69 J/g), indicating its melting point. The FTIR spectra of atorvastatin calcium-dipicolinic acid multicomponent solids indicated an intermolecular interaction that was thought to be a hydrogen bond between the molecules of atorvastatin calcium and dipicolinic acid. The results of the solubility test showed that the atorvastatin calcium-dipicolinic acid multicomponent solids had a significantly increased solubility (p<0.05) compared to the solubility of pure atorvastatin calcium.