bluuebunny/crossref_metadata_2025 huggingface dataset:
Monitoring the Flesh Softening and the Ripening of Peach during the Last Phase of Growth On-tree
Authors: Pinto Catalina , Reginato Gabino , Mesa Karen , Shinya Paulina , Díaz Mariana , Infante Rodrigo
Published: February 2019

The aims of this study were to characterize the softening rate of the flesh and some physiological parameters of three peach cultivars during the last phase of on-tree development. During two consecutive seasons, labeled fruits were nondestructively monitored on-tree, from the stone-hardening phase up to harvest. The absorbance index of the skin (IAD) follows a segmented, nonlinear regression. Beyond the intersection point of the two segments of the regression, the IAD decreased linearly at a higher rate 10 to 15 day before harvest. The most dramatic change of the IAD coincided with the “color break” of the skin. The IAD and the flesh softening were similar in ‘Andes Du-1’ and ‘Loadel’, while there was no difference in the growth rate of ‘Bowen’ and ‘Loadel’. ‘Andes Du-1’ and ‘Bowen’ showed the same growth rate in the upper and the lower sections of the canopy. The fruit at the upper section showed a mass of 30 to 50 g greater than the fruit at the lower section. In addition, no significant changes in the evolution of the soluble solids content (SSC) were observed, with the exception of ‘Loadel’ located in the upper section of the canopy. Differences in the length of the fruit development period are strongly influenced by the accumulated temperature after bloom. The difference in the fruit mass, SSC, IAD, and background color depend on the position of the fruit on the canopy. The use of mixed models, based on repeated sampling over time allows to accurately describing the evolution of peach ripening.
Light-emitting Diodes Can Replace High-pressure Sodium Lighting for Cut Gerbera Production
Authors: Llewellyn Dave , Schiestel Katherine , Zheng Youbin
Published: February 2019

A greenhouse study was undertaken to investigate whether light-emitting diode (LED) technology can be used to replace high-pressure sodium (HPS) lighting for cut gerbera production during Canada’s traditional supplemental lighting (SL) season (November to March). The study was carried out at the University of Guelph’s research greenhouse, using concurrent replications of SL treatments within the same growing environment. LED (85% red, 15% blue) and HPS treatment plots were set up to provide equal amounts of supplemental photosynthetically active radiation (PAR) at bench level. This setup was used to assess the production of three cultivars of cut gerbera (Gerbera jamesonii H. Bolus ex Hook.f): Acapulco, Heatwave, and Terra Saffier. There were no treatment differences in SL intensity, with average SL photosynthetic photon flux density (PPFD) and daily light integral (DLI) of 55.9 µmol·m−2·s−1 and 2.3 mol·m−2·d−1, respectively. Flowers harvested from the LED treatment had a 1.9% larger flower diameter in ‘Acapulco’; 4.2% shorter and 3.8% longer stems in ‘Heatwave’ and ‘Terra Saffier’, respectively; and 7.7% and 8.6% higher fresh weights for ‘Acapulco’ and ‘Terra Saffier’, respectively, compared with flowers harvested from the HPS treatment. There were no differences in accumulated total or marketable flower harvests for any of the cultivars. The vase life of ‘Acapulco’ flowers grown under the LED treatment was 2.7 d longer than those grown under the HPS treatment, but there were no SL treatment effects on water uptake for any of the cultivars during the vase life trials. There were no SL treatment effects on specific leaf area for any of the cultivars. There were only minimal treatment differences in leaf, soil, and air temperatures. Cut gerbera crops grown with under LED SL had equivalent or better production and crop quality metrics compared with crops grown under HPS SL.
Variation for Salinity Tolerance During Seed Germination in Diverse Carrot [Daucus carota (L.)] Germplasm
Authors: Bolton Adam , Simon Philipp
Published: February 2019

Global carrot production is limited by the crop’s high susceptibility to salinity stress. Not much public research has been conducted to screen for genetic salinity stress tolerance in carrot, and few resources exist to aid plant breeders in improving salinity tolerance in carrot. The objectives of this study were to evaluate the response of diverse carrot germplasm to salinity stress, identify salt-tolerant carrot germplasm that may be used by breeders, and define appropriate screening criteria for assessing salt tolerance in germinating carrot seed. Carrot plant introductions (PIs) (n = 273) from the U.S. Department of Agriculture (USDA) National Plant Germplasm System representing 41 different countries, inbred lines from the USDA Agricultural Research Service (n = 16), and widely grown commercial hybrids (n = 5) were screened for salinity tolerance under salinity stress and nonstress conditions (150 and 0 mm NaCl, respectively) by measuring the absolute decrease (AD) in the percent of germination, inhibition index (II), relative salt tolerance (RST), and salt tolerance index (STI) of germinating seeds. All salt tolerance measurements differed significantly between accessions; AD ranged from −4.2% to 93.0%; II ranged from −8.0% to 100.0%; RST ranged from 0.0 to 1.08; and STI ranged from 0.0 to 1.38. Broad sense heritability calculations for these measurements were 0.87 or more, indicating a strong genetic contribution to the variation observed. Six accessions identified as salt-tolerant or salt-susceptible were evaluated in a subsequent experiment conducted at salt concentrations of 0, 50, 100, 150, 200, and 250 mm NaCl. Variations between mean AD, II, RST, and STI of tolerant and susceptible lines were greatest at 150 mm NaCl, validating the use of 150 mm NaCl concentrations during salt tolerance screening of carrot seed. Wild carrot accessions displayed little tolerance, and PI 256066, PI 652253, PI 652402, and PI 652405 from Turkey were most salt-tolerant.
Identification of Historic Homestead and Orchard Apple Cultivars in Wyoming
Authors: Magby Jonathan , Volk Gayle M. , Henk Adam , Miller Steve
Published: February 2019

Thousands of apple trees were planted in Wyoming’s orchards and homesteads in the 1800s, many of which are still alive today. Unfortunately, cultivar identity of these trees has mostly been lost or obscured. The purpose of this research was to identify heritage apple cultivars in Wyoming using genetic fingerprinting (microsatellite) techniques and to use this information to make recommendations on candidate cold-hardy cultivars for specialty crop and breeding programs. Leaf samples were collected from 510 heritage apple trees from 91 sites in 19 locales across Wyoming. Known cultivars from the U.S. Department of Agriculture (USDA)–National Plant Germplasm System, Seed Savers Exchange, and Washington State University apple collections were used as standards to determine cultivar identities. Overall, 328 (64%) of the previously unidentified apples trees were identified to 47 known cultivars. Fifteen of these known cultivars comprised more than 80% of the samples that were identified, with all 15 of those cultivars developed in states and countries with average temperatures or winter conditions similar to Wyoming. Seventy-one of the heritage trees were identified as the Wealthy cultivar. Other commonly identified cultivars were Haralson, Patten’s Greening, Yellow Transparent, Northwestern Greening, and McMahon. It is likely that a combination of popularity and cultivar origin affected the choice of cultivars that were grown in Wyoming. Although most original Wyoming heritage apple trees are reaching the end of their life span, many surviving trees continue to produce fruit. This strongly suggests that despite lower resistance to certain pathogens than many modern cultivars, these heritage trees should be considered for use today. The results provide insights into possible cultivars that could be grown in Wyoming and also in other states with similar harsh growing conditions.
Containerized Onion Transplants: A Management System to Enhance Growth, Yield, and Quality
Authors: Macias-Leon Maria A. , Leskovar Daniel I.
Published: February 2019

In the United States, most short-day onions are direct seeded. With this method, plant stands can be reduced because of extreme temperatures, weed pressure, and soil-borne diseases. Containerized transplants offer an alternative method of stand establishment with less seedling losses while producing uniform bulb sizes and high marketable yield. However, the use of transplants is not a widespread commercial practice because of the high cost of production. This study aims to select the best transplant strategies to improve onion crop performance in semiarid regions of southwest Texas or similar environments. Three sequential transplanting dates of early, mid, and late season (14 Nov., 8 Dec., and 9 Jan.) and two seedling densities of one seed per cell (T1) and three seeds per cell (T3) were evaluated on growth, yield, bulb quality, and phytonutrient content of three onion cultivars, two yellow (‘Caramelo’ and ‘Don Victor’), and one red (‘Lambada’). During early development, late-transplanted onions had an increase in plant height and greater leaf elongation rate than early and midtransplanted onions, whereas early plantings required more days to reach maturity than mid and late plantings. Overall, early and midtransplanting dates resulted in higher yields than late plantings. Although increasing seedling density (T3 vs. T1) did not significantly reduce marketable yield in early plantings, T1 produced a higher number of jumbo and colossal bulb sizes than T3. Onion quality was mostly affected by cultivar and not by transplant strategies. The technique of establishing onions from transplants grown from one plant per cell (T1) or multiple plants (T3) from early November to early December provides a practical and economical alternative to achieve earlier crops, while reducing the length of the production season, as planting date is delayed.
Comparison of Supplemental Lighting Provided by High-pressure Sodium Lamps or Light-emitting Diodes for the Propagation and Finishing of Bedding Plants in a Commercial Greenhouse
Authors: Craver Joshua K. , Boldt Jennifer K. , Lopez Roberto G.
Published: February 2019

High-quality young plant production in northern latitudes requires supplemental lighting (SL) to achieve a recommended daily light integral (DLI) of 10 to 12 mol·m−2·d−1. High-pressure sodium (HPS) lamps have been the industry standard for providing SL in greenhouses. However, high-intensity light-emitting diode (LED) fixtures providing blue, white, red, and/or far-red radiation have recently emerged as a possible alternative to HPS lamps for greenhouse SL. Therefore, the objectives of this study were to 1) quantify the morphology and nutrient concentration of common and specialty bedding plant seedlings grown under no SL, or SL from HPS lamps or LED fixtures; and 2) determine whether SL source during propagation or finishing influences finished plant quality or flowering. The experiment was conducted at a commercial greenhouse in West Lafayette, IN. Seeds of New Guinea impatiens (Impatiens hawkeri ‘Divine Blue Pearl’), French marigold (Tagetes patula ‘Bonanza Deep Orange’), gerbera (Gerbera jamesonii ‘Terracotta’), petunia (Petunia ×hybrida ‘Single Dreams White’), ornamental millet (Pennisetum glaucum ‘Jester’), pepper (Capsicum annuum ‘Hot Long Red Thin Cayenne’), and zinnia (Zinnia elegans ‘Zahara Fire’) were sown in 128-cell trays. On germination, trays were placed in a double-poly greenhouse under a 16-hour photoperiod of ambient solar radiation and photoperiodic lighting from compact fluorescent lamps providing a photosynthetic photon flux density (PPFD) of 2 µmol·m−2·s−1 (ambient conditions) or SL from either HPS lamps or LED fixtures providing a PPFD of 70 µmol·m−2·s−1. After propagation, seedlings were transplanted and finished under SL provided by the same HPS lamps or LED fixtures in a separate greenhouse environment. Overall, seedlings produced under SL were of greater quality [larger stem caliper, increased number of nodes, lower leaf area ratio (LAR), and greater dry mass accumulation] than those produced under no SL. However, seedlings produced under HPS or LED SL were comparable in quality. Although nutrient concentrations were greatest under ambient conditions, select macro- and micronutrient concentrations also were greater under HPS compared with LED SL. SL source during propagation and finishing had little effect on flowering and finished plant quality. Although these results indicate little difference in plant quality based on SL source, they further confirm the benefits gained from using SL for bedding plant production. In addition, with both SL sources producing a similar finished product, growers can prioritize other factors related to SL installations such as energy savings, fixture price, and fixture lifespan.
Metalized-striped Plastic Mulch Reduces Root-zone Temperatures during Establishment and Increases Early-season Yields of Annual Winter Strawberry
Authors: Deschamps Stephen S. , Agehara Shinsuke
Published: February 2019

Black plastic mulch is used predominantly for winter strawberry (Fragaria ×ananassa Duch.) production in Florida because of its warming effects. However, black plastic mulch can increase heat stress during establishment, especially when growers advance planting dates (e.g., late September) to improve earliness. Consequently, we designed a new plastic mulch film that has a metalized center stripe with black shoulders. We hypothesized that metalized-striped mulch can minimize heat stress during establishment, while maintaining the warming effects of black mulch during winter. We conducted field trials over two seasons to evaluate black mulch, fully metalized mulch, and metalized-striped mulch using two cultivars differing in heat stress tolerance and fruit production patterns: ‘Florida Radiance’ and ‘Florida Beauty’. The effect of plastic mulch type on plant growth and yield was generally consistent across both seasons. Compared with black mulch, metalized-striped mulch reduced afternoon root-zone temperature (RZT) by up to 3.1 °C and reduced the duration of heat stress conditions (RZT > 30 °C) by 119 hours across October and November, but exhibited equivalent soil warming during winter. Yield increases by metalized-striped mulch compared with black mulch ranged from 19% to 34% in the early season (November–January), 6% to 20% in the late season (February–March), and 12% to 26% over the entire season. Statistical significance was detected for the 2016–17 early-season yield and when yield data were expressed on a weekly basis. Compared with black mulch, metalized-striped mulch improved fruit number significantly without affecting fruit weight or canopy area, suggesting that heat stress on black mulch negatively affects flower and fruit development more than plant growth. Weekly fruit yield data indicate that metalized-striped mulch can produce greater yields than fully metalized mulch. Metalized-striped mulch is an easily implementable strategy for reducing establishment heat stress and improving fruit earliness in subtropical winter strawberry production regions.
Diversity of Bacterial and Fungal Communities in Wheat Straw Compost for Agaricus bisporus Cultivation
Authors: Cao Guangtian , Song Tingting , Shen Yingyue , Jin Qunli , Feng Weilin , Fan Lijun , Cai Weiming
Published: February 2019

The Agaricus genus represents the most popular edible mushroom in the world. Wheat straw often is used as the substrate for mushroom cultivation following pretreatment to degrade the lignocellulosic biomass in agricultural waste. In this study, we investigated the changes in bacterial and fungal microflora of wheat straw substrate during different phases of composting. We collected samples of the raw material (M1), phase I aerobic fermentation (F1, F2, F3), and phase II after-fermentation (AF1) for high-throughput 16S rRNA and internal transcribed spacer (ITS) sequencing to analyze the microbial diversity in the substrate during composting. Our data revealed that among the five stages, 365 operational taxonomic units (OTUs) were shared, with Firmicutes, Proteobacteria, and Actinobacteria being the predominant bacterial phyla. In addition, Thermobispora, Thermopolyspora, Ruminiclostridium, Thermobacillus, and Bacillus were the predominant genera in F3 and AF1, with the species Thermobispora bispora and Pseudoxanthomonas taiwanensis being predominant in F2. Both principal component analysis (PCA) and nonmetric multidimensional scaling (NMDS) plots showed that the bacterial communities of five stages could be distinguished from each other based on their composting time. The Shannon and Simpson indexes of F2 were lower than M1 (P < 0.05), and the clustering dendrogram showed that the bacterial communities in AF1 were similar to F3, with Micromonosporaceae, Streptosporaceae, Thermomonosporaceae, and Vulgatibacteraceae representing the differential bacterial families by linear discriminant analysis with effect size (LEfSe) analysis. The analysis of fungal communities showed that 384 OTUs were common among the five stages, with 1054 and 454 OTUs unique to M1 and AF1, respectively. Ascomycota and Basidiomycota were the two predominant phyla in all stages, and Chytridiomycota was predominant in F2, F3, and AF1 stages. PCA and NMDS plots showed that the clusters of F2 and AF1 were more dispersed than the other stages. No differences were observed in alpha diversity between the stages, and samples of F1, F2, and F3 were closer to AF1 in the clustering dendrogram. By LEfSe analysis, Mycothermus thermophilus, Gonapodya polymorpha, and Phaeophleospora_eugeniae were identified as the predominant fungal species in AF1.
Micropropagation to Conserve the Endangered Gabal Elba Dragon Tree (Dracaena ombet Heuglin ex Kotschy & Peyr)
Authors: Dewir Yaser Hassan , Aldubai Abdulhakim A. , Al-Obeed Rashid Sultan , El-Hendawy Salah , Seliem Mayada Kadri , Al-Harbi Khadija Rabeh
Published: February 2019

Plant tissue culture offers opportunities for the rescue and conservation of endangered plant species. Here, we report the successful in vitro propagation of Dracaena ombet, an endangered plant. Several physical and chemical seed treatments were evaluated to develop a propagation approach. Germination of D. ombet seeds was monitored for 16 weeks by placing them onto Murashige and Skoog (MS) medium. Maximum seed germination (20%) was recorded when seeds were soaked-scarified, whereas all other treatments did not result in seed germination. Fragmented (longitudinally bisected) and intact in vitro shoots were cultured onto MS medium supplemented with various concentrations of 6-benzylaminopurine (BAP) and indole butyric acid (IBA) to induce axillary shoots. Longitudinal fragmentation of explants had a greater effect than the intact explants for shoot proliferation when cultured onto medium containing plant growth regulators. Fragmented shoots cultured onto MS medium supplemented with 2 mg·L−1 BAP and 0.5 mg·L−1 IBA treatment resulted in the highest amount of axillary shoots (seven shoots per explant). The intact shoots had the highest axillary shoots (1.8 shoots per explant) when cultured onto a medium supplemented with a combination of 1 mg·L−1 BAP and 0.5 mg·L−1 IBA. One hundred percent rooting was obtained using half strength MS medium supplemented with 0.5 or 1 mg·L−1 IBA. With full strength MS medium, a maximum rooting of 60% was obtained with 1 mg·L−1 IBA or naphthalene acetic acid (NAA) addition. The plantlets were acclimatized to ex vitro conditions with a 95% survival rate. This study offers a simple method for in vitro propagation of D. ombet, which is valuable to enable conservation of this endangered species.
Using learning styles in learning objects: a case study in a colombian public university
Authors: Pérez-Gutiérrez Boris
Published: February 2019

AbstractBackground: computer-programming courses aren’t easy to study. Some authors have studied the difficulties in learning programming to support developing learning materials for basic programming courses. In Colombia there is an approach to teaching programming using an active learning approach (Interactive Learning Objects – ILOs) as one of the components that reinforce their pedagogical model, by supporting the generation of high-level programming skills. Objective: we want to explore the possibilities of using Learning Styles and Team Learning to increase the learning levels of Computer Programming students. Methods: this study was applied outside of the classroom in order to encourage autonomous learning. To do this we’ll pick a sample and apply a series of comparative tests between research groups. Results: the objective was met by effectively showing that providing content based LS and team-based leaning can improve a student’s performance. The intervention group grades were better than those of the comparison group though they should be analyzed further to get a more accurate conclusion. Conclusion: This study will give us the chance to see whether the strategy can be applied to the Francisco de Paula Santander University students.Keywords: Active learning, informal learning, learning objects, learning styles, team-based learning Resumen  Antecedentes: la programación de computadores es un tema difícil de aprender. Algunos autores han estudiado las dificultades en el aprendizaje de la programación para soportar el desarrollo de materiales de aprendizaje para los cursos básicos de programación. En Colombia hay un enfoque para enseñar programación usando aprendizaje activo (Objetos Interactivos de Aprendizaje) como uno de los componentes que refuerzan el modelo pedagógico, al apoyar la generación de habilidades de programación de alto nivel. Objetivo: se busca explorar las posibilidades al utilizar Estilos de Aprendizaje y Aprendizaje en Equipo para mejorar en los estudiantes los niveles de aprendizaje de programación. Métodos: este estudio se aplicó fuera del salón de clase para fomentar el aprendizaje autónomo. Para esto se seleccionó una muestra y se aplicaron una serie de pruebas comparativas entre los grupos de investigación. Resultados: el objetivo se cumplió al mostrar que efectivamente que esta estrategia puede mejorar el desempeño de un estudiante. Las calificaciones del grupo de intervención fueron mejores que las del grupo de comparación, sin embargo, estos resultados deben analizarse a profundidad para obtener una conclusión para exacta. Conclusión: este estudio nos dará la oportunidad de revisar si esta estrategia puede aplicarse a los estudiantes de la Universidad Francisco de Paula Santander.Palabras clave: Aprendizaje activo, aprendizaje basado en equipos, aprendizaje informal, estilos de aprendizaje, objetos de aprendizaje.
KHAZANAH ULAMA NUSANTARA : Tafsir Murāh Labīd Karya Nawawi Banten
Authors: Muttaqin Tsalis
Published: February 2019

In the history of Islamic development has well noted thatthere was an Indonesian Islamic scholar that very much respected bymost of the Islamic scholar in the Middle East. In fact, he has gottenhonorary title Sayyid Ulama Hijāz. One of his famous work is MurāhLabīd. A side of making us, especially as Indonesian Muslim society beproud to that great work, this book also very much compatible to theIndonesian society, in which the majority are following Imam Syāfi‟īfor their fiqh mazhab. This book has well known by pesantrencommunity in Indonesia, as well as the other Syaikh Nawawi works
Considerações acerca da cultura filistina: A seriedade da existência e a Arte como distração e entretenimento
Authors: Silveira João Eduardo Navachi da
Published: February 2019

O presente artigo analisa as críticas que o jovem Nietzsche dirigiu à concepção de arte vigente na cultura alemã da segunda metade do século XIX, em particular as críticas apresentadas em O nascimento da tragédia e na Primeira consideração intempestiva. Longe do potente significado que a arte possuía nas tragédias de Ésquilo e Sófocles, a arte moderna, diante da “seriedade da existência” e na esteira da tendência de Eurípides, seria apenas representação de uma cultura vazia e sem substância. Se entre os gregos do período de Sófocles, a arte possuiria um sentido existencial profundo, na modernidade, ela apareceria como mero instrumento de distração e entretenimento. Como procuraremos demonstrar, o filósofo da Basileia salienta inclusive a pobreza de sentido e a torção semântica que as obras de grandes compositores como Beethoven, Haydn e Wagner teriam adquirido nas mãos de determinados tipos humanos tomados como referência na época. Segundo ele, mesmo quando os filisteus da cultura [Bildungsphilister] se referiam aos grandes artistas ou gênios, em tom supostamente elogioso, eles assim o faziam de forma equivocada e canhestra. Assim, buscando ressignificar e redimensionar o papel da arte na cultura alemã moderna, Nietzsche critica o exaltado escritor da época David Strauss, enxergando nele uma espécie de modelo humano ou expressão lapidar da cultura filistina.
Unique Influences on American Indian Relationship Quality: An American-Indian and Caucasian Comparison
Authors: Gray Alexander C , Shafer Kevin , Limb Gordon E , Busby Dean M
Published: February 2019

We compare American Indians and Caucasians on the influence of family-of-origin quality on the adult-children’s later romantic relationship quality. Using data from the RELATE, 341 American Indians and 341 Caucasian participants were analyzed using group comparison methods. Structural equation modeling demonstrated that, overall, the perceived impact of family-of-origin mediated the significant influence of family-of-origin on later adult romantic relationship stability and satisfaction. However, for American Indians, the quality of the father-child relationship did not directly or indirectly influence the child’s later adult relationship quality. Still, a large portion of the father-child and mother-child relationship and quality of the parent’s marriage explains a large portion of the variance of the child’s overall perception of the impact of his or her family. Additionally, group comparison methods demonstrated that American Indians generally reported lower values on family-of-origin quality measures and relationship stability. However, they had comparable relationship satisfaction and father-child relationship quality ratings. Findings suggest that historical trauma and collectivistic cultural patterns may at least partially explain these observations. Several suggestions are made to guide interventions for American Indian families.
Families in the Future: Stories of Finnish Students
Authors: Forsberg Hannele , Nätkin Ritva
Published: February 2019

The question of the future of families emerges as a topic especially during times of rapid social change and uncertainty. Typically, the trends of the future are anticipated on the basis of existing expert knowledge. However, the interest of this paper will be in ordinary people, especially young adults’ knowledge and ways of envisioning the future from their position in life. The approach is based on an interpretative, fictive and narrative perspective to the future, using the role-play method with students. As a result, three different story types of the futures of families are found: families can strengthen, families can weaken or a catastrophe threatens families and puts them in danger of being destroyed. In all of these future stories the young adults explain the changes in families in terms of economy, values and religions, family policy and ecological factors. The results add to knowledge of how culture and values reshape family change.
Multi-Perspective Tolerance Evaluation of Bacillus Calmette-Guerin with Interferon in the Treatment of Non-Muscle Invasive Bladder Cancer
Authors: Steinberg Ryan L. , Thomas Lewis J. , Mott Sarah L. , O’Donnell Michael A.
Published: February 2019

Background:

Bacillus Calmette-Guerin (BCG) toxicities have been reported but with relative agranularity regarding severity and temporal changes during therapy. In its most severe form, BCG intolerance remains poorly understood and exploring ways to optimize toleration of the most effective treatment (BCG) is prudent.

Objective:

To report the results of both patient- and physician-centered metrics of BCG toxicity as part of the National Phase II BCG/Interferon (IFN) study, as well as the efficacy of low-dose BCG/IFN for previously deemed BCG intolerant patients.

Methods:

Patients were treated with 6 weekly treatments of BCG (various dosing based on prior BCG exposure) with 50 million units of IFN. BCG intolerance was strictly defined. Maintenance BCG was instituted if disease free. Treatment tolerance during induction was measured using physician- and patient-completed evaluations. Linear mixed effects regression was used to evaluate differences.

Results:

533 BCG naïve, 415 BCG failure, and 37 BCG intolerant patients were enrolled. There was no significant difference in quality of life scores between groups ( p = 0.70). A predictable temporal toxicity pattern was identified in all groups with symptom resolution by day 2-3. Despite BCG intolerant patients having significantly worse bladder pain/spasms and cystitis, treatment discontinuation was under 4%. Recurrence-free survival was similar between naïve and intolerant patients.

Conclusions:

BCG toxicity is common and follows a predictable pattern. While at slightly increased risk of toxicity, BCG intolerant patients may be managed successfully with 1/10th dose BCG with IFN.
Impact of yoga based mind-body intervention on systemic inflammatory markers and co-morbid depression in active Rheumatoid arthritis patients: A randomized controlled trial
Authors: Gautam Surabhi , Tolahunase Madhuri , Kumar Uma , Dada Rima
Published: February 2019

Background:

Recovery of patients with rheumatoid arthritis (RA) depends on several physical and psychological factors, besides pharmacological treatment. Co-morbid depression adversely affects the outcome in RA. Usual medical therapies have a limited scope and fail to cure the psychological component of the disease. With advanced therapeutic options, achieving a state of remission has become the treatment goal, yoga based mind body intervention (MBI) may provide a holistic approach in its treatment dimension. Hence, MBIs are the need of hour as majority of diseases have a psychosomatic component.

Objective:

To explore the effect of Yoga based MBI on disease specific inflammatory markers and depression severity in active RA patients on routine disease modifying anti-rheumatic drugs (DMARDs) therapy.

Methods:

A total of 72 RA patients were randomized into 2 groups: yoga group (yoga with DMARDs) and control group (DMARDs only). Blood samples were collected pre and post intervention for primary outcome measurements of systemic biomarkers. Disease activity score 28, erythrocyte sedimentation rate (DAS28ESR) and health assessment questionnaire disability index (HAQ-DI) were used to assess disease activity and functional status respectively at pre and post intervention time-points. Secondary outcome, depression severity, was assessed by Beck Depression Inventory II scale (BDI-II) at 2 weekly intervals during 8 weeks of the study interventional plan.

Results:

After 8 weeks of yoga based MBI, there was significant decrease in the severity of RA as seen by reduction in levels of various systemic inflammatory markers as well as in DAS28ESR ( p-value <0.0001; effect size = 0.210) and HAQ-DI ( p-value 0.001; effect size = 0.159). Also, yoga group experienced a statistically significant time dependent step-wise decline in depression symptoms over the period of 8 weeks as compared to control group ( p-value <0.0001; effect size = 0.5). Regression analysis showed greater reduction in the scores of BDI-II with DAS28ESR (R2 = 0.426; p <  0.0001) and HAQ-DI (R2 = 0.236; p = 0.003) in yoga group.

Conclusions:

Yoga, a mind body intervention re-established immunological tolerance by aiding remission at molecular and cellular level along with significant reduction in depression. Thus in this severe autoimmune inflammatory arthritis with a major psychosomatic component, yoga can be used as a complementary/adjunct therapy.
Fundamento teórico para el análisis de impacto de la Ley Paez en el norte del Departamento del Cauca, como estudio de caso de innovación territorial y desarrollo local.
Authors: Aguilar Erazo Francisco Javier
Published: February 2019

El artículo determinó el marco teórico para la investigación denominado ANALISIS DE IMPACTO DE LA LEY PAEZ EN EL NORTE DEL DEPARTAMENTO DEL CAUCA, COMO ESTUDIO DE CASO DE INNOVACION TERRITORIAL Y DESARROLLO LOCAL, enmarcado en el macro proyecto de investigación establecido por la Universidad Politécnica Estatal del Carchi del Ecuador, dentro del componente de Innovación Territorial, denominado MODELOS DE GESTIÓN PARA ACTORES SOCIALES BASADO EN DIAGNÓSTICO DE REALIDADES DE BIENESTAR, PARA EL DESARROLLO ECONÓMICO SUSTENTABLE Y SOSTENIBLE EN LA PROVINCIA DEL CARCHI.Bajo los objetivos propuestos por el proyecto de investigación, se define como fundamento teórico el concepto de Desarrollo Territorial establecido por el Economista Chileno SERGIO BOISIER, donde busca interpretar el desarrollo local de un territorio a partir del concepto de capital, del cual trasciende a cinco enfoques para entender el proceso de transformación social y productivo de un territorio, siendo estos el Enfoque Productivo, donde se vislumbra el Modelo de Desarrollo Endógeno; el Enfoque Cultural denotando la interacción entre el capital humano y social; el Enfoque Ambiental a través del desarrollo sostenible y sustentable; el Enfoque Urbano Regional, donde se analizó el alcance de integración territorial y finalmente, el Enfoque Político-Institucional, como criterio de legitimidad de las acciones gubernamentales entorno al desarrollo territorial.De esta manera, se determinó bajo este enfoque teórico, el análisis de impacto de la población objetivo, como un estudio de caso de Innovación Territorial y Desarrollo Local, partiendo de la interacción sistemática e integral de los enfoques de Desarrollo Territorial establecidos por BOISIER.
Analisis Pola Migrasi Penduduk di Dataran Tinggi Kabupaten Aceh Tengah Provinsi Aceh (Dimensi Sosial, Ekonomi, dan Infrastruktur)
Authors: Zulhilmi Muhammad , Maulana Hafiizh
Published: February 2019

Kebijakan pengendalian jumlah penduduk di Kabupaten Aceh Tengah dihadapkan pada persoalan penurunan kualitas penduduk dengan tingginya jumlah imigran yang masuk. Penelitian ini ingin menjawab serangkaian permasalah migrasi dengan menelaah secara mendalam pola migrasi penduduk dan faktor-faktor yang mempengaruhinya. Penelitian dilakukan pada 14 kecamatan di Kabupaten Aceh Tengah, dengan model estimasi migrasi data cross section. Model migrasi yang dihasilkan membagi model dalam lingkup sosial, ekonomi/ketenagakerjaan, dan infrastruktur. Pola migrasi risen yang masuk di Kabupaten Aceh Tengah secara sosial dipengaruhi oleh faktor pendidikan, beban ketergantungan yang tinggi, fasilitas kesehatan. Sementara dalam lingkup ekonomi, tingkat partisipasi angkatan kerja dan jumlah penduduk bekerja menambah tingginya migrasi risen yang masuk.Dalam lingkup infrastruktur penduduk akan bergerak secara masif terjadi karena faktor akses perumahan dan sumber penerangan listrik. Pemerintah Kabupaten Aceh Tengah diharapkan dapat responsif dalam membuat perencanaan pembangunan yang berbasis kependudukan dengan memperhatikan faktor migrasi penduduk di daerah tersebut.
CFD investigation on steady and unsteady performances of contra-rotating propellers
Authors: Kaewkhiaw Prachakon
Published: February 2019

The realistic flow on each blade of the front and rear propellers with contra-rotating propellers (CRPs) are most complex because that consist the interaction forces with themselves and it affects to the actual efficiency of the propeller blades. The wake of CRPs at the gap between the front and rear propellers have influent to the variation of propeller performance for the front and rear propellers. So, this paper presented the numerical simulation of propeller performance on CRPs with steady method in the first. Second, it is applied to evaluate the propeller performance with unsteady method in time accuracy including investigating the wake on a transverse plane between the front and rear propellers and a transverse plane located downstream of the rear propeller. The wake was analyzed through velocity vector magnitude contours. The numerical simulations were conducted using the Reynolds Averaged Navier-Stokes (RANS). The calculation results have been compared the measurement data.
Sinop Yarımadası Kıyıları (Güney Karadeniz, Türkiye) Makroalg Topluluklarının Zamansal Değişimi
Authors: Karaçuha Ali , Yıldız Gökhan , Ersoy Karaçuha Melek
Published: February 2019

Bu
çalışmada, Karadeniz’in Sinop Yarımadası çevresindeki mevcut denizel makroalg
türlerinin dağılımı ve biyokütlesindeki
mevsimsel değişimler
incelenmiştir. Örneklemeler Eylül 2013-Temmuz 2014 tarihleri arasında 2-5 m
derinlikler arasında yer alan dokuz farklı istasyonda gerçekleştirilmiştir. Alg
örnekleri tüple dalış yapılarak metal bir çerçeve (20x20cm) ile üç tekerrürlü
olarak elle toplanmıştır. Araştırma sonucunda, 6’sı Chlorophyta, 6’sı
Ochrophyta ve 18’i Rhodophyta olmak üzere toplam 30 takson tespit edilmiştir.
İstasyonlar genelinde tespit edilen en baskın türler Cystoseira crinita Duby, 1830 (%53) ve Cystoseira barbata (Stackhouse) C.Agardh, 1820 (%37) olup bunu Polysiphonia fucoides (Hudson) Greville,
1824 ve Ceramium spp. türleri izlediği
tespit edilmiştir.  İstasyonlar genelinde
ortalama en yüksek biyokütle değeri 8861.9 gm-2 (yaş ağırlık)ile
Taşocağı istasyonunda, en düşük değer ise Ayı İni Koyu (4006.8 gm-2)
istasyonundan elde edilmiştir. Örnekleme boyunca tespit edilen biyokütle değerinin
2150.6 gm-2 (Karakum
istasyonu, yaz mevsimi) ile 10947.2
gm-2 (Taşocağı istasyon, ilkbahar) arasında değişim gösterdiği
saptanmıştır. Bu çalışma ile Karadeniz’in Sinop Yarımadası kıyılarındaki
makroalg türleri ve biyokütlelerindeki mevsimsel değişikliklere değinerek
dinamikler bilgisine katkıda bulunulmaya çalışılmıştır.
La locura de Don Quijote. Ideología y literatura en la novela cervantina
Authors: Martínez Torrón Diego
Published: February 2019

No disponible.
Don Quijote como Sileno: ¿Una pista para descifrar las intenciones de Cervantes?
Authors: Iffland James
Published: February 2019

No disponible.
Loaysa: visión cervantina de un mito clásico
Authors: Berrio Pilar
Published: February 2019

No disponible.
El caballero del Verde Gabán y el caballero de los Leones: la plenitud del encuentro
Authors: Vivar Francisco
Published: February 2019

No disponible.
El personaje de Sancho Panza y los lectores del siglo XVII
Authors: Salazar Rincón Javier
Published: February 2019

No disponible.
Pastores en el 'Quijote'
Authors: López Estrada Francisco
Published: February 2019

En el Quijote un hidalgo de la Mancha pierde el juicio por leer libros de caballerías e imitar las aventuras que cuenta esta literatura. Lee también libros de pastores, pero los pastores existen en su realidad social y es un oficio de las gentes del campo. Sancho declara haber sido pastor. La poesía de Garcilaso atrae a su señor don Quijote, y en una ocasión se la muestra en prosa a Sancho. Dulcinea es el nombre que da don Quijote a su amor, y parece nombre de pastora. Unos cabreros oyen un discurso pastoril que les dirige don Quijote. Y unos pastores lo acercan a Sierra Morena al entierro de Grisóstomo, que ha muerto de amor por Marcela. También asiste a la preparación de las bodas de Camacho, un rico pastor, y ayuda a que la novia se case con Basilio, un pastor pobre. Finalmente, don Quijote es derrotado como caballero por un amigo que quiere que se retire a la aldea. Obligado a regresar a su casa por un acuerdo con el que lo ha vencido, entonces él y sus amigos y vecinos, se preparan para vivir a la manera pastoril, y el hidalgo recobra la razón, y así muere cuerda y cristianamente.
Una continuación dieciochesca del Quijote: la Historia del más famoso escudero Sancho Panza
Authors: Pérez García Norberto
Published: February 2019

La Historia del más famoso escudero Sancho Panza es una de las más características continuaciones del Quijote del siglo XVIII. Tras situar la obra en su contexto, el artículo traza un estudio comparativo (coincidencias episódicas, en personajes, estructura y estilo; y diferencias sustanciales entre las dos novelas) para mostrar el alcance de la consideración cervantina durante esta época.
Alquimia y atomismo en el Quijote
Authors: García-Verdugo Caso Carlos
Published: February 2019

En la época de publicación del Quijote aún no se han escindido los lenguajes humanista y científico. En el presente trabajo se han indagado pasajes de la novela que hacen posible relacionar ambos ámbitos del conocimiento. Ello permite entender las ideas que una persona culta de la época posee sobre lo que, en un sentido amplio, conocemos como ciencia. Además, ciertas ideas científicas se utilizan de manera creativa desde el punto de vista literario. Entender dichas ideas conlleva el conocer con mayor riqueza aspectos puramente artísticos de la obra. Esa relación simbiótica se circunscribe en este trabajo al ámbito alquímico en sus diversas manifestaciones. También es posible encontrar rastros de atomismo.
El año cervantino en Serbia
Authors: Stojanovic Jasna
Published: February 2019

En este trabajo, realizado en la Cátedra de Estudios Ibéricos de la Facultad de Filología de Belgrado, se reúnen los datos sobre la recepción de la obra cervantina en Serbia durante 2005. La presencia del autor y la difusión de su obra han sido analizadas a través de varias actividades artísticas, científicas y culturales organizadas a lo largo del año. Atención especial han merecido las nuevas traducciones de títulos cervantinos y las nuevas críticas. Asimismo, se ha elaborado una bibliografía completa del material editado con motivo de la conmemoración.
Les deux Amantes (1705): una traducción preciosista de Las dos doncellas, novela ejemplar de Miguel de Cervantes
Authors: Iñarrea Las Heras Ignacio
Published: February 2019

En el presente artículo se ofrece un análisis de las principales similitudes y diferencias entre Las dos doncellas, una de las Novelas ejemplares de Miguel de Cervantes, y Les deux Amantes, versión francesa de esta narración, publicada en 1705. Se pretende mostrar, en primer lugar, que el traductor ha añadido a la historia original influencias literarias cuyo origen está en el movimiento preciosista francés del siglo XVII. En segundo lugar, se desea hacer ver cómo, en última instancia y a partir de las aportaciones del Preciosismo, el autor de Les deux Amantes ha utilizado la creación de Cervantes para dar expresión a ideas más personales, concernientes a la defensa de la libertad de la mujer.
Espejismos y desengaños en la Nápoles virreinal: los Viajes al Parnaso de Cervantes y Cortese
Authors: Gagliardi Donatella
Published: February 2019

Miguel de Cervantes y Giulio Cesare Cortese compartieron la misma aspiración a entrar en la corte literaria del séptimo conde de Lemos en la Nápoles virreinal. Escudándose en su magisterio poético, ambos reivindicaron la legitimidad de tal ambición, destinada, sin embargo, a un doloroso fracaso. En este artículo se analizan motivos y tonos comunes a sus respectivos sueños parnasianos, dedicando especial atención al Viaggio de Cortese, sobre cuyos temas arroja nueva luz el estudio de un cancionero inédito del padre de la poesía napolitana.
Tradición y dinámica editorial: hacia una renovadora visión crítica de la obra de Miguel de Cervantes. La labor editorial de la Academia del Hispanismo
Authors: Arlandis Sergio
Published: February 2019

No disponible
El mito de Dánae en El curioso impertinente: Terencio, Tiziano y Cervantes
Authors: De Armas Frederick A.
Published: February 2019

Uno de los mitos clásicos que aparecen en la novela intercalada cervantina, El curioso impertinente, el del rapto de Dánae, no ha recibido mucha atención crítica. Las muchas imágenes visuales de la novela cervantina recuerdan la écfrasis de este mito en el Eunuco de Terencio, donde la pintura es una de las causas del rapto de Pánfila. La novela cervantina se hace eco de la controversia que había suscitado el Eunuco, comenzando con San Agustín; controversia que continuó hasta el Siglo de Oro con escritores tales como Juan de Mariana y Juan de Pineda. El estudio de la comedia de Terencio y de la pintura de Dánae enviada por Tiziano a Felipe II ayudan a comprender la importancia del mito como elemento temático y estructural en la novela. La historia de Dánae en Cervantes forma parte del debate sobre el impacto de las artes visuales en la época de la Contrarreforma.
El amante liberal y la importancia del territorio en la cuestión matrimonial
Authors: López Rubio Lucía
Published: February 2019

La novela El amante Liberal sitúa la trama en el conflicto territorial entre cristianos y otomanos, los personajes sortean y conocen muy bien ambas legislaciones para conseguir darle a sus aventuras el final deseado, las nupcias. Sin embargo, para el lector actual la interpretación y combinación de ambas normativas legales y sociales resulta un aspecto desconocido. A lo largo del artículo realizaré un análisis de los puntos clave que ambas sociedades imponen en torno a la cuestión matrimonial, lo cual exige un estudio del derecho musulmán, de los cánones del Concilio de Trento y de los manuales escritos por los principales humanistas sobre el comportamiento óptimo en la sociedad de los Siglos de Oro.
De lo que aconteció cuando Martín Sarmiento se subió a la zebra del moro Muzaraque y encontró a Cervantes en el camino de Alcalá
Authors: Santos Puerto José , Santos Vega Elena
Published: February 2019

En este estudio se recuerda la importancia que tuvo Martín Sarmiento en el descubrimiento de Alcalá como lugar de nacimiento de Cervantes. Según exponen los autores, la novedad no fue planteada previamente por Juan de Iriarte, como afirmó su sobrino en una carta publicada por Juan Antonio Pellicer, sino únicamente por el benedictino Sarmiento, debido a una triple coincidencia en la primavera de 1752: primero, la redacción del escrito Sobre la Zebra, que llevó a Sarmiento a consultar documentos y textos antiguos, para explicar que las cebras abundaban y se cazaban en la España medieval; segundo, la asociación de la cebra con Cervantes en el Diccionario de la Real Academia; y tercero, la adquisición de la obra de Diego de Haedo en esas mismas fechas. Los autores recuerdan, por otra parte, la inexistencia de datos que avalen que Martínez Pingarrón se anticipó a Agustín Montiano para conseguir la partida de bautismo de Cervantes.