bluuebunny/crossref_metadata_2025 huggingface dataset:
Novel Mosquito Net Nearly Halves Malaria Infection in Community Trials in Tanzania
Authors: Rowland Mark
Published: August 2022

A novel class of bed net that kills mosquitoes resistant to traditional insecticides by making them unable to move or fly, significantly reduces malaria infection in children, according to new research published in The Lancet public health journal. Unlike other insecticides which
kill the mosquito via the nervous system, the effects of the new bed net means the mosquito dies from muscle paralysis, being unable to undertake cellular respiration, continue flying or blood feeding. A two-year community randomised trial involved more than 39,000 households and followed
over 4,500 children aged 6 months to 14 years in Tanzania. It found that a longlasting insecticidal net treated with two insecticides, chlorfenapyr and the pyrethroid alpha-cypermethrin (chlorfenapyr LLIN), reduced the prevalence of malaria by 43% and 37% in the first and second year respectively,
compared to a standard pyrethroid only long-lasting insecticidal net (LLIN). The chlorfenapyr LLIN also reduced clinical episodes of malaria by 44% over the two years and the number of malaria-carrying mosquitoes sampled in exit traps by 85%.
Технології створення High-Poly моделей у пакеті Blender 3D
Authors: Бойцова М. , Ломовцев П. Б. , Бойцова О. С.
Published: August 2022

У роботі розглянуто процес розробки асетів для комп’ютерних ігор за професійним пайплайном, етапи моделювання та текстурування, акцентовано увагу на технологіях OpenGL та PBR. В роботі пропонується оптимальне поєднання технологій та програмних засобів для створення якісного проекту для подальшого використання як унікальних ігрових об’єктів.  Особливу увагу приділено питанню оптимізації моделей на етапі роботи з сіткою, розлянуто ряд автоматичних засобів і виконано порівняння в ефективності з ручними методами. З метою прискорення роботи та економії цифрових ресурсів виконується ряд технічних задач : виконання ретопології, розгортки моделей, запечення карт нормалей. Продемонстровано технології високоякісного рендерингу в реальному часі для створення фінальної демонстрації готових асетів.
Дослідження методів соціальної інженерії. Частина I. Вплив на здоров’я людини.
Authors: Селіванова А. В. , Левитський Ю. О.
Published: August 2022

Представлена робота присвячена дослідженню впливу методів соціальної інженерії (СІ) на здоров’я людини.
В процесі роботи досліджено визначення терміну соціальна інженерія, його популярність, алгоритм дії соціальних інженерів (СІн), методи впливу СІ на людину, види агресивного психологічного впливу на особистість у кіберпросторі, засоби подолання наслідків впливу методів СІ на людину, інформаційні системи, що інформують про методи СІ та їх вплив на здоров’я людини.
Проведено збір даних методом опитування, що характеризує вплив дії СІн на здоров’я людей. Отримані дані оброблені за допомогою засобів інтелектуального аналізу даних  із використанням інструментальних засобів Google  та Orange. Розроблено модель впливу СІ на здоров’я людини.
Результати дослідження було впроваджено у аналітичну платформу KitStat у якості оновлення, що дозволяє надати інформаційну підтримку та забезпечити продовження збору даних для подальшого дослідження. 
В процесі проведення дослідження використано такі засоби та технології як  Google Forms, Google Analytіcs, Orange, мови HTML5, CSS3, PHP, JavaScript.
Результати дослідження можуть бути використані як фахівцями при дослідженні методів СІ так і звичайними людьми для захисту від дії соціальних інженерів.
From A. A. Zimin’s Scholarly Heritage: The Publication of the Poganaya Kniga
Authors: Khoruzhenko Oleg
Published: August 2022

This work publishes a previously unknown paper by Aleksandr Aleksandrovich Zimin (1920–1980), an outstanding Soviet historian, source study specialist, and archaeographer, discovered in the personal archive of his student Margarita Evgenyevna Bychkova (1936–2014). It is a publication of the so-called Poganaya Kniga prepared following several copies. The Poganaya Kniga is a genealogical pamphlet of the seventeenth century based on the Votskaya Pyatina cadastre from 1500 by scribe Dmitry Kitaev. In the Poganaya Kniga, several noble families were ranked among serfs (kholopy) who received estates in Novgorod Land after its annexation by the State of Muscovy. A. A. Zimin repeatedly referred to this source in his research and, as it transpires, he was preparing its publication. This work was never completed; Bychkova was supposed to continue it as an acknowledged specialist in the textual study of genealogical books. However, having supplemented Zimin’s publication with the variants found in the copies she had identified, she did not publish it for some reason. Considering the scale and scholarly significance of A. A. Zimin’s and M. E. Bychkova’s papers, the author assumes that this publication of the Poganaya Kniga will be of interest to those dealing with source studies and historiography.
Eyewitnesses to the Phenomenon of Russian Cold: Robert Boyle and the Accounts of Early Travelers North
Authors: Jansson Maija
Published: August 2022

This article examines the Russian cold as reflected in accounts of early travelers to the north. For his study of the phenomenon of cold in the early 1660s, Robert Boyle repurposed parts of Giles Fletcher’s travel account of Russia written seventy-seven years earlier. Inspired by Sir Francis Bacon’s work on heat, Boyle sought to understand the extremes of cold but found himself hampered by its absence in northern England. Consequently, he turned, among other sources, to the printed account of Ambassador Fletcher who, sailing north on a Muscovy Company ship, had kept a journal following the Instructions and Ordinances drafted for that Company by Sebastian Cabot. Boyle found verification of the accuracy of Fletcher’s eyewitness description of cold through his friends and compatriots in the Royal Society who had been to Russia. Ultimately, this is the story of the impact of England’s mid-sixteenth century navigational technology and commercial and diplomatic relations with Russia on Robert Boyle’s late seventeenth century early scientific study of cold which, according to the author’s conclusion, demonstrates how the study of the Russian north impacted the early development of natural science in England.
The National and Confessional Policy of P. N. Wrangel’s Regime
Authors: Kalinovsky Vladimir , Samylovskaya Ekaterina
Published: August 2022

This paper examines the main directions of P. N. Wrangel’s national and confessional policy in Crimea in 1920. The study aims to determine the specifics of national and confessional policy implementation during P. N. Wrangel’s political regime regarding various population groups. The research methodology relies on the principles of critical analysis of periodicals and private sources, many of which have never been studied previously. More particularly, the authors talk about data from Crimean newspapers published in 1920 (such as Yuzhnye Vedomosti, Tavricheskiy Golos, Krymskiy Vestnik, etc.), which are practically unknown to researchers, as well as the memoirs of the participants of the events, i. e. officers and residents. Due to the peculiarities of the era, these materials are the foundation for the qualitative development and understanding of the state policy implementation in the ethno-confessional sphere. The fundamental innovation of this work is a comprehensive approach to the issue. The authors try to analyse the actions of the national and ethnic communities of Crimea at the final stage of the Civil War. They emphasise the importance of the national question in the activities of the government in the South of Russia, as well as identify the historical features of the region, which traditionally influenced the ethnic and religious lifestyle, which the new administration could not disregard. The main results of the study are related to the demonstration of the following provisions: in contrast to A. I. Denikin’s regime, P. N. Wrangel’s regime made fundamental concessions regarding national and confessional groups, paying attention to the Crimean Tatars. At the same time, at the official level, the regime positioned itself primarily as Orthodox, which was emphasised in its leaders’ rhetoric and propaganda. Attention is paid to such a little-known story as the emigration of certain ethnic groups from Crimea during P. N. Wrangel’s regime.
Don’t We Have Enough in Russia, a Handful, to Feed Our Own?! Letters of Citizens to the Authorities of Besieged Leningrad
Authors: Piankevich Vladimir
Published: August 2022

This article examines written petitions of residents of besieged Leningrad to the city leaders. The author refers to approximately four hundred letters kept in the archival fund of the Food Commission of the Military Council of the Leningrad Front, as well as evidence of citizens’ appeals to the leaders of Leningrad from official documents, diaries, letters of the siege, memoirs, and later interviews. The study makes it possible to identify the needs, interests, aspirations, dissatisfaction, and hopes of many Leningraders. Also, it helps make conclusions about the reasons and purposes of writing petitions, their structure, content, and how the appellants perceived themselves, the situation in the city, and the authorities in the conditions of the siege. The article examines the form, language, and style of letters to the authorities, the types of paper used, and the peculiarities of writing letters. Petitions to the city leaders were not common practice. However, the very appearance of appeals and the content is significant evidence of the situation in Leningrad, the moral and psychological state, and the survival strategies of the besieged. Many Leningraders referred to their merits and tried to convince the addressee of their need, understanding the pragmatic attitude of the authorities to the city’s population. Often the appeal was a cry for help from a desperate person. Letters from individuals facing the siege alone and dependent’s rations received were especially dismal. The inequality that transpired in the conditions of the siege and the difference in nutritional norms caused discontent. The article analyses letters that were particularly critical of workers in the supply and trade spheres, which reflected the sentiments prevalent in the besieged city. Also, the author examines petitions containing proposals, criticism, and accusations against those in power. The article provides the results of the analysis of written appeals from the siege and the dominance and reasons for the authorities’ refusal to help. In accordance with their attitudes, ordinary siege survivors were supposed to be victorious heroes but in no way pathetic “moral weaklings” and victims. The author concludes that the letters to the authorities paradoxically combined a commitment to paternalism, a desire to take advantage of the possibilities of the state distribution system, its privileges and benefits on the one hand, and initiative and self-reliance, on the other.
Factors associated with the intermediate probability of heart failure with preserved ejection fraction on the H2FPEF score in asymptomatic patients in rotation work conditions in the Arctic
Authors: Vetoshkin A. S. , Shurkevich N. P. , Simonyan A. A. , Gapon L. I. , Kareva M. A.
Published: August 2022

Aim. To study the factors associated with the intermediate probability of heart failure (HF) with preserved ejection fraction (HFpEF) according to the H2FPEF score (Heavy; Hypertensive; Atrial Fibrillation; Pulmonary Hypertension; Elder; Filling Pressure) in asymptomatic patients in rotation work conditions in the Arctic.

Material and methods. In the polar village of Yamburg (68° 21’ 40” northern latitude), 100 men and 80 women with grade 1, 2 hypertension and normotensive persons were examined on the basis of the Medical Unit of OOO Gazprom Dobycha Yamburg. All patients underwent echocardiography using generally accepted methods of imaging and data processing, according to European Society of Echocardiography guidelines. To calculate the probability of HFpEF, the H2FPEF score was used. The Bruce protocol treadmill test was performed. The SF-36 (Health Status Survey) questionnaire for assessment of life quality was used.

Results. Group 1 included 95 male and female patients with a low probability of HF (H2FPEF score — 0-1), group 2 — 85 patients of both sexes with an intermediate probability of HF (H2FPEF score — 2-5). Group 2 patients were older (p=0,038), worked longer on a shift (p=0,0143), and had higher ambulatory systolic (p=0,0001) and diastolic blood pressure (p=0,0013) with a higher body mass index (BMI) (p=0,0001). Based on the odds ratio (OR) analysis, the factor most strongly influencing the intermediate probability of HFpEF was BMI (OR=1,261, 95% confidence interval (CI): 1,140-1,393). SF-36 questionnaire revealed intergroup differences only on the role functioning scale (p=0,013) with lower values in group 2. In the logistic regression model, dyspnea during the treadmill test occupied a leading position as follows: OR=8,952; 95% CI: 3,454-15,197 (p<0,0001). The second place was taken by inotropic reserve value (OR=1,020; 95% CI: 1,006-1,035 (p=0,005), which was higher in group 2 and was regarded as one of the compensatory mechanisms for adapting to stress. In the group 2, echocardiography revealed significant differences in terms of left ventricular (LV) myocardial mass (p=0,0002), LV internal area (p=0,0002), isovolumic relaxation time (p=0,003), and ratio of transmitral diastolic flow rate to mean mitral annulus velocity (p=0,0001), which indirectly indicates the presence of LV diastolic dysfunction.

Conclusion. There are following factors associated with H2FPEF intermediate probability of HFpEF in asymptomatic patients on shift in the Arctic: BMI, length of shift, dyspnea and an increase in inotropic reserve during exercise due to a decrease in adaptive potential, impaired LV diastolic function. Initiating management strategies that target identified factors in patients with asymptomatic HF may slow symptomatic disease progression in shift workers in the Arctic region.
Prevalence of myocarditis, genetic cardiomyopathies and their combinations among patients of the Cardiology Hospital of the V.N. Vinogradov Faculty Therapeutic Clinic of the Sechenov University
Authors: Ruchkin D. V. , Nartova A. A. , Zaitseva A. I. , Lutokhina Yu. A. , Blagova O. V. , Alijeva I. N. , Sarkisova N. D. , Nedostup A. V.
Published: August 2022

Aim. To establish the prevalence of myocarditis and primary (genetic) cardiomyopathies (CMP) among patients in a cardiology hospital.

Material and methods. Medical records of 671 patients of the cardiology department were analyzed. The diagnosis at admission and at discharge was recorded. The diagnoses were divided into 7 following categories: hypertension, coronary artery disease, heart disease, idiopathic arrhythmias, cardiomyopathy, myocarditis and others. Types of myocarditis and cardiomyopathy, the presence of arrhythmias and heart failure were also recorded.

Results. Myocarditis was diagnosed in 194 (28,9%) patients, cardiomyopathy — in 76 (11,3%) patients, combination of cardiomyopathy and myocarditis — in 26 (3,9%) patients. Myocarditis with the development of arrhythmia and heart dilatation prevailed as follows: 47,4 and 41,2%, respectively. The most numerous CMPs were left ventricular noncompaction (n=30), non-inflammatory dilated CMP (n=13), hypertrophic CMP (n=10) and arrhythmogenic CMP of the right ventricle (n=9). In the group with idiopathic arrhythmias, 64,3% of patients were diagnosed with myocarditis, and 19,4% — with cardiomyopathy.

Conclusion. The prevalence of non-coronary myocardial diseases among patients in a cardiology hospital is high and amounts to 40,2%. The presence of arrhythmias, heart failure or dilated cardiomyopathy may be a manifestation of non-coronary myocardial diseases, and requires a comprehensive examination aimed, in particular, at ruling out or verifying the diagnosis of myocarditis.
Comparative retrospective analysis of the prevalence of deep vein thrombosis detected by duplex ultrasound in primary health care facilities
Authors: Rozykhodzhaeva G. A. , Zhuraev Z. A.
Published: August 2022

Aim. To identify the incidence of deep vein thrombosis (DVT) as determined by compressive duplex ultrasound in primary health care facilities before and during the pandemic of a coronavirus disease 2019 (COVID-19).

Material and methods. This retrospective analysis of 1492 duplex ultrasound examinations in 2018 and 1710 examinations in 2020-2021 in patients with suspected lower limb DVT was performed. The studies were carried out in 4 primary health care institutions in different cities of the Republic of Uzbekistan. Each patient underwent duplex ultrasound of lower limb deep veins. Most patients had complaints (swelling, leg pain) (symptomatic patients), while some individuals underwent preventive screening before various surgical interventions and had no complaints (asymptomatic patients).

Results. According to the data obtained, the prevalence of DVT increased significantly during the pandemic — from 3,9 to 15,1% (χ2=113,23, p<0,001). During the pandemic, there was a trend towards a relative increase in lower limb DVT among the elderly and young people — by 8,7 and 3,8%, respectively (χ2=1,66, p=0,19 and χ2=0,64, p=0,42, respectively). No dependence of the prevalence of lower limb DVT on the sex was found (χ2=0,02, r=0,9).

Conclusion. The study results showed an increase in the prevalence of lower limb DVT during the COVID-19 pandemic. Further clinical studies are needed to analyze the lower limb DVT during this period.
Verification of subclinical carotid atherosclerosis as part of risk stratification in overweight and obesity: the role of machine learning in the development of a diagnostic algorithm
Authors: Druzhilov M. A. , Kuznetsova T. Yu. , Gavrilov D. V. , Gusev A. V.
Published: August 2022

Aim. Comparative analysis of mathematical models obtained using multivariate logistic regression (MLR) with stepwise inclusion of predictors and machine learning (ML) for assessing the probability of subclinical carotid atherosclerosis in normotensive overweight and obese patients without cardiovascular diseases and/or diabetes.

Material and methods. We received data on patients from the Webiomed platform database. The inclusion criteria were age ≥18 years, body mass index ≥25 kg/m2, extracranial artery ultrasound results, while the exclusion criteria included diabetes and/or cardiovascular disease. MLR analysis was carried out with stepwise inclusion of predictors. ML algorithms were used to create an alternative model.

Results. The overall percentage of true results for MLR model was 73,2%, while the proportion of true negative and positive predictions was 80,1% and 63,4%, respectively. Mathematical models created using ML methods are characterized by a predictive value from 75 to 97% with a sensitivity of 77 to 92% and a specificity of 80 to 98%.

Conclusion. A significant superiority of ML models was revealed in the study of available clinical and paraclinical parameters. Integration of ML mathematical models into a diagnostic algorithm for making a decision to refer a low-risk patient for extracranial artery ultrasound will significantly improve its accuracy and cost efficiency.
Features of immittance spectra as performance indicators for cement-based concretes
Authors: McCarter W. John , Suryanto Benny , Abdalgadir Hussameldin Taha , Starrs Gerry , Kim Jaehwan
Published: August 2022

Design for durability and performance-based standards and specifications for reinforced concrete infrastructure is limited by the lack of rapid, science-based test methods for characterising the deterioration resistance of concrete. In this paper, this issue is addressed though the application of two-point electrical impedance measurements taken within the frequency range 100 Hz–10 MHz. Data are presented for a range of industry-standard cement-based concrete mixes with and without supplementary cementitious materials. Nyquist plots (−iZ″(ω) against Z′(ω)) and Bode plots (Z*(ω) and θ against frequency) clearly highlight the frequency dependence of the electrical response. However, when presented in the form of permittivity and conductivity, a region of dispersion was evident over the entire frequency range for all concretes. The features of this response, which could be gainfully exploited as durability indices for assessing the long-term performance of concrete, are identified and discussed. A range of formalisms is presented and it is shown that, within this frequency range, conductivity was found to obey Jonscher's universal power law. Two novel durability parameters are presented based on features of Jonscher's model; from a practical viewpoint, the power-law model can be evaluated using conductivity measurements obtained at three, easily measured, spot frequencies (10 kHz, 1 MHz and 10 MHz).
Evaluation of micro-metakaolin and ferric chloride solution in stabilising expansive soils
Authors: Sakr Mohamed A. , Azzam Wasiem R. , Meguid Mohamed A. , Hassan Asaad F. , Ghoneim Hebatalla A.
Published: August 2022

Expansive soils are generally characterised by their volume change when subjected to variation in water content. This may result in significant damage to supported and nearby structures. In this study, the swelling properties of bentonite material as an expansive soil are first determined. The expansive soil is then improved using two different approaches, namely, micro-metakaolin (Mm) and ferric chloride (FeCl3) solution. The optimum percentages for both additives are determined using laboratory experiments, which are 25 and 1% for the Mmand the ferric chloride solution, respectively. The free swell index of the bentonite after being treated with Mmand ferric chloride solution at the optimum percentages is found to decrease by about 54 and 62%, respectively. Meanwhile, the swelling pressure for the expansive soil decreased by 33 and 43% when mixed with the same optimum values of Mmand ferric chloride solution, respectively. On the basis of the results obtained in this study, the addition of ferric chloride solution achieved better results compared with Mm. This improvement technique may be used to enhance the properties of expansive soils that support different construction engineering projects.
Modelling the pedestrian crossing choice in urban streets (case study of Qazvin city)
Authors: Mirbaha Babak , Minuee Mahnoosh , Rassafi Amir Abbas , Layegh Maziyar
Published: August 2022

Pedestrians are the most vulnerable road users in traffic accidents. This study analyses the effective factors in choosing the type of crossing by pedestrians. The required data were collected through interviews based on the pedestrian behaviour scale questionnaire and video images of crossing pedestrians in Qazvin city. The observed variables such as individual characteristics, crossing choices, traffic volume and the role of latent variables of pedestrian behaviours are considered on crossing choices. Latent behavioural variables were identified through exploratory factor analysis and were divided into positive and negative habits. In addition, structural equation model, traditional binary logit and hybrid discrete choice model were used in this paper. The results show that men are less likely to use a pedestrian overpass compared to women. In addition, young people in the age group of 18–30 and 30–45 are more eager to use overpasses compared to older ones. Furthermore, negative behavioural habits such as distraction and inattention, error and violation resulted in choosing a riskier alternative compared with level crossing. Furthermore, positive behavioural habits such as daily walking had a positive effect on choosing a safer crossing alternative (pedestrian overpasses). The findings are useful in developing policy measures to build safe and efficient facilities.
Recomendaciones para la valoración psicológica o psiquiátrica forense en víctimas de violencia contra la pareja en Colombia
Authors: Charry Lozano Liliana , Cabezas-Charry Ana Gabriela
Published: August 2022

Este estudio se propone plantear recomendaciones que puedan servir de insumo inicial para la realización de una guía o procedimiento de valoración psicológica o psiquiátrica forense en víctimas de violencia contra la pareja (vcp), que cumpla las exigencias de la normatividad nacional e internacional, ya que no se ha publicado ninguna guía o procedimiento forense en este sentido por parte del Instituto Nacional de Medicina Legal y Ciencias Forenses en Colombia. La vcp es una realidad humana y un problema de salud pública. Los datos de la investigación científica demuestran que la vcp es un fenómeno complejo, en su mayoría bidireccional, heterogéneo, multicausal e independiente del género [1]. Se realiza un estudio descriptivo, de características retrospectivas, en que se revisa la normatividad existente, los enfoques explicativos actuales y la atención forense en Colombia, complementada con la revisión de las guías publicadas en la región para las valoraciones psicológicas o psiquiátricas forenses en los últimos diez años. En las guías revisadas se recomienda que mediante la entrevista clínico-forense y la administración de instrumentos de evaluación adecuados se constate la existencia de violencia, se estime si el testimonio ofrecido es congruente con la información de la literatura sobre violencia psicológica y se valore las repercusiones psicológicas o psiquiátricas en la víctima para así determinar el nexo causal. Valorar el impacto de la victimización en vcp permite apoyar la investigación judicial y contribuir a mejorar la calidad de vida de las víctimas y a restaurar el estado previo a la vivencia traumática.
Sexual harassment
Authors: Cabeza-Monroy Gina , Perea-Fernandez Ivan
Published: August 2022

Sexual harassment is a set of physical, verbal or non-verbal behaviors of a sexual nature that has the effect of an affront to the dignity of a person by creating intimidation, hostility, humiliation, offense or a degrading environment. The Colombian penal code requires as conditions to prove a case of sexual harassment: first, to demonstrate that the victim has been harassed, persecuted or besieged; second, the sexual purposes in favor of the victimizer or third parties; third, there is no consent in the victim; fourth, a relationship of imbalance of power in favor of the victimizer and against the victim. The recommendations for the forensic evaluation include: Framing into the socio-cultural context of the evaluated person; Recolection of the story identifying the psychic trace and the emotional, social and physical effects of the sexual harassment and the closing of the interview -closing the psychic wounds that could be opened with the psychological exploration and not revictimize-; Make a succinct and clear expert report informing if there is a vital risk to the authority, the treatment recommendations and if you find fictitious sexual harassment.
On the unsuitability of a vibrating sample magnetometer for measuring the magnetization curves of magnetic fluids
Authors:   Institute of Continuous Media Mechanics UB RAS, Lebedev A. V.
Published: August 2022

The magnetization curves of magnetic fluid samples were measured using a vibrating sample magnetometer (VSM) and the differential run method. For standard magnetic fluids, the VSM gives significantly underestimated values of magnetization. In the case of a solid sample of a magnetic fluid based on epoxy resin, there is a complete coincidence of the magnetization curves obtained by the two measurement methods. The last experiment was performed with a styrene-based sample. It was initially measured with the use of the VSM in a liquid state. Then the sample was polymerized (without being removed from the magnetometer) and repeated measurements were performed. The magnetization curve of the liquid sample was noticeably lower than that of the polymerized sample.
TİROİD İNCE İĞNE ASPİRASYONLARINDA İNCELENEN PREPARAT SAYISI İLE TANI ARASINDAKİ İLİŞKİ
Authors: TAN Ayça , İŞİSAĞ Aydın
Published: August 2022

Amaç

Tiroid nodüllerinin tanısında kullanılan tek yöntem

olan ince iğne aspirasyonunu değerlendirmede en

yaygın kullanılan sistem Bethesda sistemidir. Semptomatik

ve asemptomatik nodüllere uygulanan ince

iğne aspirasyonunun yeterliliği hastanın uygun takip

ve tedavisi için önemlidir. Çalışmanın amacı tiroid nodüllerinden

yapılan aspirasyonlarda hazırlanan preparat

sayısı ve aynı anda örneklenen nodül sayısı ile

tanısal yeterlilik arasındaki ilişkiyi değerlendirmektir.

Gereç ve Yöntem

3747 olguya ait 5092 ince iğne aspirasyonu çalışmaya

alındı. Olguların yaş ve cinsiyeti, nodül çapı, nodül

başına örneklenen preparat sayısı, aynı seansta örneklenen

nodül sayısı ve tüm nodüllerin tanıları not

edildi. Preparat sayısı ve örneklenen nodül sayısı

parametreleri kategorize edilerek tanı ile arasındaki

ilişkiye bakıldı. Tüm veriler SPSS 20 programı kullanılarak

analiz edildi.

Bulgular

İnce iğne aspirasyonlarının 3929’u (%77,2) kadın,

1163’ü (%22,8) erkek hastalardan yapılmıştı ve yaş

ortalaması 52,3 (11-93 yaş) idi. Tek preparat ile incelenmiş

aspirasyonlarda tanısallık oranı multipl preparat

ile incelenenlere göre daha düşük idi (p=0,001).

Multipl preparat ile incelenenlerde kuşkulu grup ve

malign tanıları daha fazlaydı, tek preparat incelenenlerde

ise benign tanı oranı daha yüksek idi (p=0,013).

Tanı kategorilerine bakıldığında ise multipl nodülden

yapılan aspirasyonlarda benign tanılar daha fazlayken,

tek nodül aspirasyonlarında kuşkulu ve malign

tanı daha fazla idi.

Sonuç

Aspirasyon yapılan nodülün ultrasonografik özellikleri

ve yapılan işlemin doğruluğu tanıyı doğrudan etkilemektedir.

Nodülden yapılan aspirasyonlarda nodülün

birkaç alanından aspirasyon yapılması ve aspirasyonların

tek preparata kıyasla iki ya da daha fazla

preparat ile hazırlanmasının hem tanısallığı artırmak

hem de kuşkulu ve malign tanı olasılığını artırmak için

önemli olduğu sonucuna varıldı.
EVALUATION OF THE ELASTICITY AND THICKNESS OF THE HEEL FAT PAD WITH ULTRASOUND IN PLANTAR FASCIITIS
Authors: BİÇEN Ahmet Çağdaş , YILDIRIM Utku Mahir , UNAL Meric
Published: August 2022

Objective

The aim of this study was to evaluate thickness and

elasticity of heel fat pad in patients with unilateral

plantar fasciitis and to investigate the effects of age,

sex, body mass index (BMI), and functional scores on

plantar fasciitis.

Material and Method

70 patients who had been suffering from unilateral

plantar fasciitis longer than 6 months were enrolled

in the study. The thickness and elasticity of fat pad

were compared between the painful and healthy feet

of the patients with ultrasound. For measurement of

elasticity, shear wave elastography (SWE) was used.

Comparative analysis was performed for thickness

and elasticity variables between the painful and

healthy feet with Mann–Whitney U and independent

samples t-test.

Results

Average of age of the patients was 44±11.66. The

average thickness of the heel fat pad was 17.9±3.1

mm on the affected side and 18.3±3.3 mm on the

healthy side. The mean SWE value of the painful side

was 23.9 m/s (range 9.3-32) and was 24.7 m/s (range

10.8-34) on the healthy side. Heel fat pad thickness

was greater in the healthy feet than in the painful feet,

but there was no statistical significance (p=0.448).

The painful feet were stiffer, but the difference was

statistically similar (p=0.347). BMI had a statistically

significant impact on thickness of heel fat pad.

Conclusion

The results showed that a decrease in the heel fat pad

thickness was a supporting finding of plantar fasciitis

in patients with normal BMI but not in patients with

BMI>25.
FOURNİER GANGRENİ HASTALARINDA VAC KULLANIMININ HASTANE YATIŞ SÜRESİNE ETKİSİ
Authors: CANLIKARAKAYA Fırat , TERZİOĞLU Serdar Gökay , AKINCI Felat
Published: August 2022

Amaç Bu çalışmada fournier gangreni hastalarında vakum yardımlı yara kapatması (VAC) kullanımının hastanedeki yatış süresini azalttığını göstermek amaçlanmıştır. Gereç ve Yöntem Bu bir retrospektif çalışma olup hastanemize 1 Haziran 2019- 31 Ocak 2022 tarihleri arasında başvurup fournier gangreni tanısı alan 78 hastanın bilgilerinin hastane kayıt sisteminden incelenmesiyle oluşturulmuştur. Karşılaştırmalarda Student T testi kullanılmış olup p değeri
CUT&RUN Chromatin Profiling of Human Kidney Tissue v1
Authors: Robbins Lynn
Published: August 2022

Histone post-translational modifications are key epigenetic features that define gene regulatory elements in the genome. Identifying changes in the epigenome has the potential to uncover novel disease signatures. Chromatin immunoprecipitation with sequencing (ChIP-seq) is a commonly used method to define the chromatin landscape. A limitation of this method is that the amount of starting material (≥106 cells) does not lend itself to interrogation of kidney biopsies. Cleavage Under Targets and Release Using Nuclease (CUT&RUN) is a recently described method that provides genome-wide mapping of chromatin profiles for histone binding. In this method, cells are immobilized on beads, permeabilized with detergent (digitonin) and incubated with an antibody that recognizes specific histone post-translational modification in nucleosomes, DNA binding proteins (e.g., transcription factor) or other factors that associate with chromatin. After antibody binding, a fusion protein of Micrococcal nuclease and protein A/G (pAG-MNase) is added. The protein A/G moiety binds the antibody and the nuclease cuts accessible chromatin adjacent to the nucleosomes. The released DNA fragments, representing the genomic regions enriched for antibody binding, are column purified and used to construct a library for sequencing. Sequence is aligned to the human genome and peaks that represent statistically significant binding (e.g., histone H3 lysine 27 trimethylation, H3K27me3) are called using the Model-based Analysis for ChIP-seq Method (Macs2) that we have adapted for CUT& RUN.
Halal Education: Curriculum Management Based on Halal Entrepreneurship at Nahdlatul Ulama University of Sidoarjo
Authors: Anam Fatkul , Istiq’faroh Nurul
Published: August 2022

Indonesia is well-known for having the world’s largest Muslim population. As a result, Indonesia has significant halal market potential. After forming the Institute for the Study of Food, Drugs, and Cosmetics in the Indonesian Ulema Council, halal products became more widely known (LPPOM-MUI). Since then, public awareness and demand for Halal products have risen significantly, making Indonesia a lucrative market for halal businesses. In response to the rapid rise of the halal industry, a new curriculum has emerged in education to meet the difficulties of today’s industrial world. Halal entrepreneurship is a newly designed university program. This study was implemented to determine the curriculum management based on halal entrepreneurship at the Nahdlatul Ulama University of Sidoarjo. The result of this study can be reflected in the well-run and methodical planning, execution, and evaluation stages. The curriculum development team incorporates halal entrepreneurship into courses and teaches halal materials in halal food management, halal cosmetics, and halal supply chain management. At the end of each lecture, students participate in curriculum evaluation exercises used to improve the curriculum in the future.
Politología y netnografía: Una alternativa para la investigación online en la educación superior
Authors: Liccioni Edith
Published: August 2022

La introducción de las tecnologías que llevan el aula a los hogares y la implementación de nuevos modelos educativos implica cierta dificultad y no está supedita a la selección de un programa, sino a la multiplicidad de elementos generadores de transformaciones. La facilidad para acceder a todo tipo de información a través de la web ha generado que estudiantes, docentes e investigadores en la educación superior (área de ciencias políticas) sean atraídos por las nuevas tecnologías. Esto conlleva a plantear la necesidad de introducir opciones metodológicas para dar cuenta de fenómenos emergentes, complejos y múltiples en las casas de estudio de educación superior ecuatorianas. Así, el objetivo del estudio fue describir la netnografía como alternativa para potenciar el desarrollo de investigaciones online relacionadas con las ciencias políticas en la educación superior de Ecuador. Se optó por una investigación descriptiva con diseño biblográfico de tipo documental. El instrumento aplicado fue la matriz de análisis de contenido. Se utilizó una muestra teórica de 25 artículos científicos. Los resultados evidencian la potencialidad del método netnográfico por sus cualidades metodológicas de flexibilidad, adaptabilidad, poder descriptivo y, especialmente, su naturaleza multimetódica. Se concluye que se abre una amplia gama de oportunidades de relevancia para las investigaciones online en la educación superior en el área de las ciencias políticas, pues se presenta como un método eficaz para promover la comprensión de las señales culturales de esferas sociales encubiertas y poco representativas, pero que encuentran en la virtualidad un espacio fértil para proporcionar información natural para su desarrollo y manifestación.
Trece ideas en torno a la emergencia de las ciencias jurídicas reveladas por la pandemia global de la Covid-19: Del pacto social al reino de la ciencia
Authors: Córdova Edgar Rafael , Quintana Pérez Bleidis Vanessa
Published: August 2022

La gobernabilidad del Estado social de derecho se examina a partir de las decisiones asumidas por el gobierno en nombre de la bio política, a partir de la aparición de la COVID-19 (marzo de 2020). El presente trabajo tiene por objetivo interpretar las relaciones entre los acuerdos políticos, económicos y sociales que se derivan de ese diseño institucional en la que se fundamentó la gobernabilidad en la sociedad moderna pre Covid-19, y por otro lado las decisiones de los gobiernos, a propósito de la declaratoria de pandemia por la Organización Mundial de Salud-OMS). Se procedió a analizar el contenido y las formas presentes en las decisiones de gobiernos que determinaron el periodo de confinamiento y los procesos de flexibilización posteriores. Como conclusión se establece que elementos para la construcción de una sociedad pos pandémica dependerá en buena parte de la fortaleza a institucional democrática para el mantenimiento de las libertades y protección propias del estado de derecho, ya que de no existir tal fortaleza institucional esta relación pondría en peligro para la sociedad de libertades.
Discussion on the Construction of New Media Language “XX Ben X”
Authors: Niu Saichen
Published: August 2022

The new construction of new media language “XX běn X” has a fixed structure, consisting of the constant term “běn” and two variables “XX” and “X”. Its initial construction “kěài běn ài “ comes from “kě’ài běnrén”, indicating that this construction directly comes from the expansion of “referring to person nouns/personal pronouns + běnrén”. The expansion of “běn NP” affects its construction changes. The Chinese characters/syllables of the variable “X” are selected from the components of the variable “XX”. The selection mechanism is determined by semantic and prosodic factors, with semantic factors taking precedence. The variable “XX” can be general nouns, proper nouns and adjectives, mostly new media language words referring to a certain type of people, with high productivity. “XX běn X” means that the reference object is the typical “XX”, which is often used to evaluate in an exaggerated manner, and has strong resonance in the new media language community.
Jornal do professor: a voz do magistério do estado de Pernambuco (1955-1962)
Authors: Anjos Iracema Santos Carvalho dos , Ávila Virgínia Pereira da Silva de
Published: August 2022

Este texto propõe analisar as características e as principais notícias veiculadas no Jornal do Professor, com enfoque na divulgação das ações do Centro de Professorado Primário de Pernambuco (CPPP), no período entre os anos de 1955 e 1962. O exame ocorreu nas matérias publicadas nas 84 páginas dos exemplares do periódico, localizado no Arquivo Público Estadual de Pernambuco, em Recife (PE). A delimitação temporal compreende o primeiro ano de circulação do Jornal do Professor até o último disponível neste arquivo. Trata-se de pesquisa histórico-documental, que se insere na perspectiva da História Cultural e da História e Historiografia da Educação. O conjunto de matérias do Jornal do Professor evidencia as fragilidades das políticas educacionais destinadas ao magistério pernambucano, entre elas, a diferença nos vencimentos conforme a delimitação espacial. Além disso, os professores e professoras que viviam na zona rural sofriam com a desvalorização, o que gerou uma situação de descrédito do magistério, e a condição de povo esquecido em matéria de educação, justamente em um momento de expansão da educação e do ensino elementar no Brasil.
ОПРЕДЕЛЕНИЕ 151Sm В ПРОБАХ ПОЧВЫ С ИСПОЛЬЗОВАНИЕМ МЕТОДА ЖИДКОСТНОЙ СЦИНТИЛЛЯЦИОННОЙ СПЕКТРОМЕТРИИ
Authors: Сальменбаев Саян Елеусизович , Берикхан Кайыржан Асетулы , Мухамедияров Нурлан Жумагазыевич , Жамалдинов Фаиль Фиргатович , Харченко Артем Алексеевич , Мустафина Куралай Тасбулатовна
Published: August 2022

Ссылка для цитирования: Определение 151Sm в пробах почвы с использованием метода жидкостной сцинтилляционной спектрометрии / С.Е. Сальменбаев, К.А. Берикхан, Н.Ж. Мухамедияров, Ф.Ф. Жамалдинов, А.А. Харченко, К.Т. Мустафина,  // Известия Томского политехнического университета. Инжиниринг георесурсов. – 2022. – Т. 333. – № 5. – С. 100-107.

Актуальность исследования обусловлена отсутствием информации об уровнях содержания в почвах Семипалатинского испытательного полигона техногенного радионуклида 151Sm. Расчетное количество 151Sm, которое могло быть рассеяно во время наземных и атмосферных испытаний ядерных зарядов, проведенных на Семипалатинском испытательном полигоне, составляет 6,1·105 Ки. Как известно, почва является депонирующей системой, накапливающей различные токсичные, вредные вещества и радионуклиды. В результате ветровой и водной эрозии почв, поглощения радионуклидов растениями, может происходить их дальнейшее перераспределение и миграция, в результате чего радионуклиды могут поступать в организм человека, приводя к его облучению. Цель: разработка способа радиохимического определения 151Sm в почвах Семипалатинского испытательного полигона с использованием метода жидкостной сцинтилляционной спектрометрии. Объекты: поверхностные пробы почвы, отобранные на территории Семипалатинского испытательного полигона. Основными критериями при выборе образцов было наличие в них 137Cs как возможного индикатора присутствия 151Sm, и отсутствие радиоактивных изотопов Eu как основного мешающего радионуклида. Значения удельной активности 137Cs в исследуемых образцах варьировали от 3,6 до 780 Бк/кг. Метод. Способ определения 151Sm включает полное кислотное разложение исследуемых образцов почвы концентрированными растворами кислот (HF, HNO3), выделение и радиохимическую очистку с использованием ионообменных смол, а также осаждение малорастворимых соединений. Удельная активность 151Sm определялась с помощью ультра-низкофонового жидко-сцинтилляционного спектрометра Quantulus 1220. Кривая эффективности регистрации 151Sm от гашения в образце была построена с использованием метода CIEMAT/NIST. Для измерения концентрации изотопов самария использовался масс-спектрометр Agilent 7700x, содержание гамма-излучателей оценивалось с помощью гамма-спектрометров ВЕ-5030 и GEM 5825. Результаты. Разработан способ определения 151Sm в пробах почвы с использованием метода жидкостной сцинтилляционной спектрометрии. Средний химический выход составил 83 %, предел обнаружения – 0,01 Бк/г для времени измерения 60 мин. Зафиксированные значения удельной активности 151Sm составили диапазон от 158 до 290 Бк/кг.
САМООЧИЩЕНИЕ ПРОДУКТИВНОГО ГОРИЗОНТА НА МЕСТЕ ПРОВЕДЕНИЯ ДВУХСКВАЖИННОГО ОПЫТА ПО ВЫЩЕЛАЧИВАНИЮ УРАНА НА ДОБРОВОЛЬНОМ МЕСТОРОЖДЕНИИ (КУРГАНСКАЯ ОБЛАСТЬ)
Authors: Сащенко Анна Владимировна , Авдонин Геннадий Иванович , Тарханова Галина Александровна , Носков Михаил Дмитриевич
Published: August 2022

Ссылка для цитирования: Самоочищение продуктивного горизонта на месте проведения двухскважинного опыта по выщелачиванию урана на добровольном месторождении (Курганская область) / А.В. Сащенко, Г.И. Авдонин, Г.А. Тарханова, М.Д. Носков // Известия Томского политехнического университета. Инжиниринг георесурсов. – 2022. – Т. 333. – № 5. – С. 137-147.

Актуальность темы обусловлена необходимостью определения природы повышенных содержаний урана в породах на месте проведения опыта двухскважинного подземного выщелачивания и мониторинга качества подземных вод для выявления их потенциальной возможности к самовосстановлению природного равновесия и условий самоочищения рудовмещающего горизонта без проведения специальной рекультивации. Цель: определение нейтрализующих свойств рудовмещающих пород по отношению к техногенным компонентам, поступающим в недра при проведении скважинного подземного выщелачивания; изучение изменения концентраций загрязняющих компонентов в пластовых водах и минерального состава рудовмещающих пород на месте проведения опыта двухскважинного подземного выщелачивания. Объект: рудовмещающие отложения и пластовые воды таборинской свиты (J2-3tb) средне-позднеюрского возраста, изученные на месте проведения натурного двухскважинного опыта (контрольная скважина 224) на Добровольном месторождении. Методы. Состав пластовых вод изучен непосредственно на месте бурения контрольной скважины; минералого-аналитическое изучение пород и руд выполнено с применением комплекса методов, в том числе и прецизионных, в лабораториях Федерального государственного бюджетного учреждения «Всероссийский научно-исследовательский институт минерального сырья им. Н.М. Федоровского»: исследования проведены на рентгеновском микроанализаторе (РСМА) JEOL JХА 8100, укомплектованном энергодисперсионной приставкой INCA, на растровом электронном микроскопе наиболее представительного образца с целью изучения химического состава, морфологии и детального характера распределения урановой минерализации. Радиоизотопные исследования осуществлены гамма-спектрометрическим методом с использованием «ORTEC-65195-P/DSPecPlus» по методике, разработанной Всероссийским научно-исследовательским институтом минерального сырья им. Н.М. Федоровского. С целью изучения влияния жизнедеятельности микроорганизмов на физико-химические свойства среды в Институте микробиологии им. С.Н. Виноградского РАН выполнены микробиологические исследования. Результаты. Выявлены остаточные после проведения двухскважинного опыта концентрации урана; определены участки переотложения урана. Установлено, что через 30 лет после проведения опыта пластовые воды на Добровольном месторождении восстановились практически до исходного состояния. Подтверждена безопасность добычи урана методом скважинного подземного выщелачивания на Добровольном месторождении.