bluuebunny/crossref_metadata_2025 huggingface dataset:
KAZAKH NATIONAL LIBERATION UPRISINGS AGAINST RUSSIAN COLONIAL POLICY: CAUSES OF DEFEATS, PECULIARITIES, RELATIONSHIPS
Authors: Kurmanalin Samat
Published: December 2024

National liberation rebellion is characteristic of colonial countries. The Kazakh people also resisted the metropolis for a long time to preserve their independence. The resistance movements were persistent. The values of honour and dignity were high. Secondly, we consider political, social, economic reasons. A bright and tragic page of Kazakh history is when the Kazakh people throughout the XIX century periodically rose to major uprisings and defended their independence. Because of unequal strength all resistance was defeated. The main reason for the defeat was the military technique between colonists and colonisers. The paper analyses the reasons for the defeat of the armed struggle against the empire. The historical significance, general patterns, interrelationships of the uprisings led by Kazakh leaders in the history of the nation will be studied.
  The rebellions were led by heroes from dynasties that enjoyed great authority in Kazakh society. One of them was Yeset Kotibaruly from the Shekty clan. The rebellion of Eset batyr was defeated in history. However, the reader and subsequent generations have created history so that it can be studied. That is its peculiarity. The national uprisings had interconnections. The leaders had not only outwardly familiar-knowledgeable, but also communicative relations. There were strongholds to each other. There was military support. Recognising bravery and valour, they followed each other. They were united by common interests against a common enemy. This is noteworthy. Because past historiography has divided the uprisings of the Kazakh people against colonialism. We subscribe to the concept of the unity of the freedom movement.
МИР БЕЗ КОЧЕВНИКОВ: ПРОБЛЕМЫ РАЗВИТИЯ ИНДЕЙСКИХ КУЛЬТУР МЕЗОАМЕРИКИ
Authors: Ужкенов Ернар
Published: December 2024

This article examines the history of Mesoamerica, focusing on specific aspects of indigenous societies. All these aspects are united by a common factor: the absence of nomadic groups, which significantly influenced the development of indigenous cultures. In turn, this highlights the role and importance of the nomadic element in fostering intercultural connections between various cultural centers, which eventually led to the creation of the unified transcontinental artery of the Old World—the Great Silk Road. Despite the remarkable achievements of Mesoamerican societies, these cultures were unable to establish a similar trade and cultural network, leading to their isolation, decline, and collapse of their unique civilizations.
Beyond trade, the absence of nomads in the cultural environment resulted in a general lag in the development of metallurgy, which saw its greatest advancements in specific regions. Similarly, military advancements, constrained by the availability of resources and the natural landscape, failed to reach a level that could withstand new invaders. All these interconnected reasons underscore the role and importance of nomadic economies as a foundation for the development of cultural societies in the Old World.
ПРОФЕССОР Қ.ЖҰБАНОВ ЖӘНЕ ҚАЗАҚ ТІЛІНІҢ ФОНЕТИКАСЫ МӘСЕЛЕЛЕРІ
Authors: Кайыров Асан
Published: December 2024

Articles, theses and major scientific works of Professor K.K. Zhubanov cover many topics. This is explained by the fact that K.K. Zhubanov was a scientist who worked in all areas of Kazakh linguistics. The main emphasis of his scientific research is made on the issues of phonetics, including the sounds of the Kazakh language, their classification by the way of sounding, acoustic and articulatory features of sounds, their terminology, Kazakh language curricula and teaching methods.
Especially important are the scientific conclusions of the scientist in the field of phonetics, such as determination of the quantity and quality of sounds of the Kazakh language, their classification, valuable remarks on the sounding of vowel and consonant sounds, analysis of types and features of vowel sounds by the way of their formation, description of types and characteristics of consonant sounds, as well as the study of the laws of synharmonism, their types and features. K.K. Zhubanov approached these questions with his own scientific view, paying special attention to specific linguistic data.
The article deals with Professor K.K. Zhubanov's views on phonetics and his importance in Kazakh linguistics. In particular, the peculiarities of classification of linguistic sounds, types of Kazakh language sounds and their phonetic characteristics on the basis of specific examples are analysed in detail.
МЕТОД ВЕНИКОВА В.А. В ПОМОЩЬ ОРГАНИЗАЦИИ ЭЛЕКТРОРЕМОНТНЫХ ПРЕДПРИЯТИЙ В УСЛОВИЯХ НЕСТАБИЛЬНОСТИ
Authors: Соловьев Дмитрий , Бакиров Сергей
Published: December 2024

Taking into account the increase in the volume of work and changes in economic conditions in the field of capital repairs of electrical equipment, especially electric motors for agriculture, the task of cost optimization is urgent. The article proposes a mathematical model that minimizes the cost of capital repairs through effective coordination of labor and material costs. The main parameters affecting the cost of repairs are determined, and a method for calculating the optimal radius for electrical repair enterprises (power lines) is developed. An important element is to take into account the uncertainty of the initial information, which makes it possible to adapt the model to various conditions using the method of V.A. Venikov. The optimal combination of labor and technical costs for major repairs is justified, which helps to reduce overall costs. The proposed solutions make it possible to improve the economic efficiency of repair processes and significantly reduce costs, which is especially important for agriculture, where the effectiveness of repairs directly affects the reduction of production costs. The development of such models is an important step towards improving the performance of electrical repair enterprises and increasing their competitiveness. The implementation of the proposed optimization model will improve the quality of repair services, improve resource management and ensure the sustainable development of repair enterprises in the field of electrical equipment in conditions of instability.
ЭФФЕКТИВНОСТЬ ПРИМЕНЕНИЯ ФИЗИЧЕСКОГО ВОЗДЕЙСТВИЯ НА ПРОДУКТИВНЫЙ ПЛАСТ ДЛЯ УВЕЛИЧЕНИЯ НЕФТЕОТДАЧИ ПЛАСТОВ
Authors: Сулейменова Райхан , Шамшенова Асира , Мукамбеткалиева Айнаш , Беркалиева Гульмира
Published: December 2024

This article assessed the technical and economic efficiency of using physical impact on the productive formation in one of the fields in Western Kazakhstan. World experience in using this technology in fields testifies to its high technological efficiency. To optimize oil production, changes in oil viscosity, increase in oil production, and decrease in water content were analyzed. All Cretaceous horizons are characterized by good reservoir properties. However, the high viscosity of oil and insufficient cementation of the rocks forming the horizons limit the complete extraction of the product. The determination of phase permeabilities in the oil-water system was carried out in laboratory conditions during stationary filtration. As a result of the use of physical impact, the viscosity of oil decreased by almost half, from 700 cP to 480 cP, which helps to increase oil production and reduce the water content in the produced products.
Pretrial Failures in Ensuring the Merit of Cases: Critical Analysis and Innovative Reconstruction
Authors: Susilo Erwin , Din Mohd. , . Suhaimi , Mansur Teuku Muttaqin , Negara Dharma Setiawan
Published: December 2024

Determining a suspect has serious implications for human rights because it has the potential to limit human freedom through arrest and detention. However, the pre-trial mechanism which should function to test whether the suspect's determination is valid or not is often ineffective because it is formal administrative in nature, moreover strengthened by Article 2 paragraph (2) PERMA No. 4 of 2016. This research uses doctrinal legal research methods to analyze legal theories and norms governing pretrial and evidence. The aim of this research is to explain the legal basis for pretrial judges' authority to examine formal aspects, analyze the implications of their weaknesses, and determine the conceptualization of assessing material aspects in pretrial to overcome these weaknesses. This research found that the formal administrative approach was caused by the use of civil procedural law in pretrial as regulated in Article 101 of the Criminal Procedure Code and reaffirmed in Article 2 paragraphs (2) and (4) PERMA No. 4 of 2016, so that pre-trials tend to only seek formal truth and are unable to prevent prosecution based on inadequate evidence. Therefore, it is proposed to expand the authority of pre-trial judges so that they can examine the substance of the evidence used in determining a suspect, including ensuring that the determination of a suspect is not based on hearsay evidence, ensure that the determination of the suspect is not based on witnesses who cannot be sworn in, ensure that there is evidence that is decisive in determining the suspect, and ensure that the testimony of witnesses or suspects is obtained without pressure or violence. This reform is expected to strengthen the implementation of Article 28D of the 1945 Constitution and increase protection of human rights by ensuring that the determination of suspects is based on valid and reliable evidence.
Análisis del costo económico directo asociado al no retiro de medicamentos por parte de los pacientes diabéticos del Área de Salud Cartago y sus implicaciones en el control de la enfermedad
Authors: Villalta Blanco María Laura  , Sánchez Araya José Miguel , Álvarez Asenjo Carolina , Cordero García  Eugenia
Published: December 2024

Objetivo: determinar los costos asociados al procedimiento de reintegro de medicamentos no retirados por pacientes con diabetes mellitus (DM) y sus implicaciones en el control de la enfermedad.
Métodos: se realizó un estudio retrospectivo-cuantitativo de pacientes diagnosticados con DM que no retiraron su tratamiento al menos una vez entre julio y diciembre de 2015. A cada paciente se le determinó el porcentaje de adherencia y se le dio un seguimiento del deterioro de los factores predictores de la enfermedad en los últimos cinco años. Para el cálculo de los costos asociados se consideró el costo de la preparación de los medicamentos no retirados y el del proceso de reintegros.
Resultados: en total, 18 pacientes diagnosticados con DM no retiraron su medicamento al menos una vez durante el periodo en estudio, lo que representó un costo de ¢331 613,42. El porcentaje de pacientes con adherencia óptima fue de 17 %, el cual es menor al reportado en otros estudios. Los resultados indican un valor HbA1C más alto en los pacientes con baja adherencia y valores más altos de glicemia en ayunas.
Conclusión: el no retiro de medicamentos genera un costo para la Caja Costarricense de Seguro Social y deja en evidencia el mal manejo de las enfermedades crónicas no trasmisibles, como la diabetes, por parte de los pacientes.
Principios y valores que deben primar en el ejercicio de la medicina
Authors: Jaramillo Antillón Juan
Published: December 2024

Todo aquel que ha ejercido la medicina en los diferentes niveles de la sociedad, desde la pobreza extrema y hasta donde priva la riqueza, tal vez se ha dado cuenta que para ejercer dicha profesión adecuadamente, esta debe ser considerada como un “apostolado social” (apóstol del griego enviar, que significa, además, mensajero).
Efecto de la pandemia por COVID-19 en la prestación de servicios de salud del primer nivel de atención de la CCSS durante el año 2020
Authors: Araya-Vega Paul , Barrantes-Arroyo Alexander , Juárez-Quesada Greivin , León-Solís Miriam , Madrigal-Loría Gustavo , Mendoza-Vega Jennifer , Rodríguez-Jiménez Elizabeth , Soto-Alpízar Shirley , Víquez-Garro Marianella
Published: December 2024

Tema y propósito: identificar el efecto que la pandemia por COVID-19 ocasionó en la mayoría de los indicadores de la Evaluación de la Prestación de Servicios de Salud (EPSS), realizada anualmente por la Dirección Compra de Servicios de Salud; además de conocer la relación entre este efecto y el comportamiento de la COVID-19 por área de salud (AS) e identificar las distintas estrategias desarrolladas para enfrentarla, así como la implementación de modalidades alternativas de atención.
Métodos: se efectuó un estudio de tipo descriptivo, cuya población de interés fueron los resultados obtenidos por 102 áreas de salud (AS) de las 105 que conformaban el primer nivel de atención en el año 2020. Estos se compararon con los resultados obtenidos en un período de referencia que cambió según el indicador. Las diferencias encontradas se contrastaron con los siguientes criterios dados por la Organización Mundial de la Salud (OMS): afectación severa: decrecimientos de 50 % o más; afectación moderada: decrecimientos entre 5,0 % y 49,9 %; y sin afectación: cambios positivos o negativos no mayores al 5,0 %. Las diferencias positivas mayores al 5 % se consideraron como evidencia de una mejoría en el indicador correspondiente.
Conclusiones: se lograron determinar los indicadores con mayor y menor afectación según los parámetros de la OMS, resaltando los referentes al tamizaje de cáncer de cuello uterino, pues la mayoría de las AS obtuvo reducciones superiores al 50 %. A nivel de Redes Integradas de Prestación de Servicios de Salud (RIPSS) destacó la Central Norte, que obtuvo reducciones mayores en el año 2020 con respecto al periodo de referencia.
Challenges and opportunities of quantum computing and its transformative potential to revolutionise various sectors and industries
Authors: Singh Ravinder
Published: December 2024

Quantum computing, leveraging the principles of quantum mechanics, is emerging as one of the most transformative technologies of the 21st century, promising computational power that can tackle problems once considered unsolvable. Unlike classical computing, which processes data in bits, quantum computing operates using quantum bits or ‘qubits’ that exploit quantum superposition and entanglement, enabling vastly superior processing power. This paper examines the challenges and opportunities presented by quantum computing, focusing on its potential to transform various industries such as healthcare, finance, education, defence, utilities and more. Additionally, the paper explores its environmental implications and impact on sustainability. A literature survey of key research contributions and a discussion of commercial timelines highlight the current state and future of this revolutionary technology. While quantum computing presents immense opportunities, its technical and economic challenges must be overcome for it to reach widespread commercial adoption. The paper concludes with an exploration of the road ahead for this nascent technology. Despite significant challenges, quantum computing offers unprecedented opportunities to transform multiple sectors, making it an essential area for ongoing research.
Dermatolojik Amaçlı Sumak Özütü İçeren Organofilik Kil-Nanokompozit Sentezi ve Biyoaktivitesinin Araştırılması
Authors: Gültek Gülay , Deniz Özcan
Published: December 2024

Killerin kozmetik amaçlı kullanımı antik çağlardan beri, terapötik kullanımı ise tarih öncesinden beri var olmuştur ve günümüz kozmetik endüstrisinde dünya çapında önemli miktarda kullanılmaktadır. Birçok kozmetik ürününde genellikle aktif içerik olarak antioksidan ve antibakteriyel bileşikler kullanılmaktadır. Bu araştırmada, kozmetik formülasyonlarda yaygın olarak kullanılan kil (montmorillonit, MMT) mineralinin kullanım amaçları doğrultusunda etkinliğinin artırılması amacıyla yenilikçi bir yaklaşımla biyoaktif organofilik naokompozitlerinin hazırlanması ve biyoaktivitesinin test edilmesi amaçlanmıştır. Bu amaçla yerli kaynaklardan alınan montmorillonit kili sedimentasyon yöntemiyle saflaştırıldı. Dodesiltrimetil amonyum klorür çözeltisi kullanılarak montmorillonit kili organofilik (OMMT) hale getirildi. Şifalı bitkiler arasında bulunan ve baharat olarak kullanılan sumak (meyve kısmı) attardan alınarak kurutuldu, öğütüldü ve su, etanol ve n-hekzan ile ayrı ayrı 8 saat boyunca Soxlet ekstraksiyon düzeneğinde özütlendi. n-kekzan özütündeki n-hekzan vakum altında uzaklaştırıldı ve elde edilen katı tekrar su/etanol çözeltisi ile özütlenerek %95 verimle gıda kalitesinde (foodgrade) sumak özütü elde edildi. Su ve etanolik ekstrakların çözücüleri de vakum altında uzaklaştırıldı. OMMT içerisindeki sumak özütü miktarı %1; %3 ve %5 olacak şekilde nanokompozitleri hazırlandı ve PEG-400 ile uyumlaştırılarak biyoaktiviteleri test edildi. Biyoaktivite testleri, deri yüzeyinde üreyen gram pozitif Staphylococcus aureus ve gram negatif bakterisi Escherichia coli kullanılarak Nutrient Agar ve Violet Bile Red Agar ortamında 37oC’de yapıldı. Üç farklı bileşimde hazırlanan kil nanokompozilerin tamamı Staphylococcus aureus ve Escherichia coli bakterilerinin üremesini inhibe ederek biyoaktif özelliğe sahip olduklarını gösterdi.
Technological Leadership Behavior and Technological Formation as Predictors of Education 4.0 Competency Determination of Educators in Region XII: A Convergent Design
Authors: Simpal Mohamad , Pidor Sylvia
Published: December 2024

This study determined the influence of technological leadership behavior and technological formation on Education 4.0 competency determination of educators in Region XII, Philippines. This study utilized mixed methods research, mainly convergent design. In the quantitative phase, adapted and validated survey questionnaires were employed, while an interview guide was utilized in the qualitative phase during in-depth interview (IDI) and focus group discussion (FGD). The statistical tools used in analyzing the quantitative data included mean, standard deviation, and multiple linear regression analysis, while thematic analysis was used for the qualitative data. The results revealed that the status of technological leadership behavior, technological formation, and Education 4.0 competency determination of educators were rated high. Moreover, technological leadership behavior and technological formation significantly influenced Education 4.0 competency determination. Further, facing limitations in the pedagogical and conceptual competencies related to Education 4.0, encountering inadequacy of resources, engaging in ICT upskilling and technology capacity-building activities, and becoming a proactive teacher were the themes generated from the lived experiences of educators. Furthermore, the themes extracted from the role of experiences that shaped their beliefs included learning is a continuous process, teaching is a vocation and bearing accountability to students. Likewise, manifesting resiliency, keeping a spirit of positivity, and embodying appropriate values were the themes generated from the experiences that shaped their attitude. Along with this, the themes that surfaced from the experiences that shaped the commitment of teachers involved visioning for knowledgeable students and manifesting passion for teaching. Finally, the nature of data integration revealed merging-converging.
Determine the Connection Between Endometriosis and Hypertensive Disorders During Pregnancy: A Systematic Review
Authors: Md Sayed Sheikh  , Ahmed Alshaikh  , Maged Elshamy  , Umme Salma
Published: December 2024

This study is designed to explore the correlation between endometriosis and hypertensive disorders during pregnancy. We looked through the Cochrane Library, PubMed and Scopus, for pertinent papers to the end of 2023. Included were full-text qualitative research studies that were published in English and provided a definitive diagnosis of endometriosis. While pregnant women without a prior endometriosis diagnosis made up the control group, pregnant women having an endometriosis diagnosis at any stage were included in the case group. The data was separately extracted and examined by two authors. A third author reviewed the entire manuscript to resolve disagreements. Data extraction and screening were done using Endnote X9. Review Manager 5.3's fixed and random effects models were employed to examine the combined data. The Downs and Black checklist were used to evaluate the included studies' quality. This analysis found that pregnancy-related hypertension disorder in 3116 endometriosis-affected women. The study confirmed that endometriosis may raise the risk of pregnancy-induced hypertension and conditions related to hypertension. Raising knowledge of hypertension diseases during pregnancy will help create screening and early diagnosis strategies that are effective.
Identifying Complex High-Risk Individuals (HRI-C) for Early Detection of Occult Pancreatic Cancers Using Risk Models and Biomarkers.
Authors: Brand Randall , Whitcomb David , Wu Bechien
Published: December 2024

Early detection and diagnosis of pancreatic cancer (pancreatic ductal adenocarcinoma, PDAC) offers the best option for effective treatment and prolonged survival. Image-based screening programs are useful in early detection of pancreatic cancers in high-risk individuals (HRI) defined by strong family history and/or pathogenic variants (PV) in hereditary cancer syndrome (HCS) genes associated with an increased risk for PDAC development. However, this only applies in about 10% of people who eventually develop pancreatic cancer.  An additional 15% of PDACs are associated with a pancreatic cystic neoplasms.  Thus, the majority (~75%) of patients diagnosed with PDAC are not candidates for surveillance under an existing framework. Based on growing evidence we believe that early detection is also possible in what we call Complex High-Risk Individuals (HRI-C) through frequent, time-limited image-based screening. These HRI-C are identified by combining multiple clinical and genetic risk factors alongside early markers of pancreatic cancer (e.g. family history, past medical history, social history, and multiple genetic factors in individuals with worrisome individual or combinations of biomarkers of occult pancreatic cancer in older individuals (>50 years) such as new onset diabetes (NOD), new idiopathic acute or chronic pancreatitis, maldigestion with exocrine pancreatic insufficiency (EPI), abnormal liver injury test (especially biliary), unexplained weight loss and typical cancer-associated pain patterns). Here we propose a potentially cost-effective clinical decision pathway aimed at improving early detection, diagnosis and outcomes of this large group of individuals at risk for developing PDAC.
A POSSIBILIDADE DE UTILIZAÇÃO DA ARBITRAGEM COMO MEIO PARA RESOLUÇÃO DE CONFLITOS NAS RELAÇÕES DE CONSUMO
Authors: Oliveira Ana Carolina Rôvere de
Published: December 2024

Este artigo examina a possibilidade da arbitragem como meio de resolução de conflitos de relações de consumo no Brasil. Em um primeiro momento, destaca-se as alterações introduzidas na Lei nº 12 e discute-se o regime jurídico do tribunal arbitral em conformidade com os princípios do Código de Defesa do Consumidor.

O presente artigo explora conceitos como princípio de competência, jurisdição e sua aplicação aos tratados de adesão, mostrando os benefícios da arbitragem, como celeridade e profissionalismo, bem como suas limitações, principalmente em relação às relações com clientes onde a vulnerabilidade do cliente exige maior proteção e garantias de equidade.
IMPACTOS AMBIENTAIS DO DESCARTE DOMICILIAR DE MEDICAMENTOS: REVISÃO DA LITERATURA
Authors: Costa Jandira Ribeiro da , Sá Nívea Silva , Sousa Matheus Oliveira Carvalho de , Araújo Franciele Alves de , Moraes Thecio Augusto Gomes de , Silva Francisco Rafael da , Gomes Francisco Antonio da Silva , Oliveira Guilherme Antônio Lopes de
Published: December 2024

The objective of this research was to analyze in the literature the impacts caused by the disposal of expired or disused medicines on the environment. The study consists of an Integrative Literature Review (IR), where the process of searching, analyzing and describing of an area of ​​knowledge takes place to answer to a specific question. The research was carried out using the following databases: United States National Library of Medicine (PUBMED), Scientific Electronic Library Online (SCIELO) and Coordination for the Improvement of Higher Education Personnel (CAPES), with the inclusion criteria being articles published between the years 2014 and 2024, with free access and available in Portuguese and English. 18 articles were selected, which highlighted the incorrect disposal of medicines by the population. With the review, it was possible to identify that the disposal of medicines in the environment causes countless damages, as they affect water sources, animals, soil and crops, causing toxic bioaccumulation.
CARACTERIZAÇÃO LABORATORIAL DE ANTICORPOS IRREGULARES COMO GARANTIA DE SEGURANÇA TRANSFUSIONAL
Authors: Lemos Maria Fernanda Ramalho Pereira , Carvalho Luane Silva , Pereira Ítalo Freitas , Magalhães Marta Gomes de , Pereira Heronides dos Santos , Silva Patrícia Maria de Freitas e
Published: December 2024

As transfusões sanguíneas podem trazer riscos ao receptor, como transmissão de doenças e o desencadeamento do processo de aloimunização, o qual ocorre quando o organismo produz anticorpos em razão da exposição a um antígeno não próprio, seja por transfusão sanguínea, gestação ou abortos espontâneos, e em menor frequência por doenças autoimunes, fatores genéticos e a alimentação. Este estudo objetivou caracterizar os anticorpos irregulares de pacientes atendidos pelo Hemocentro Regional de Campina Grande - PB, com base nos prontuários, para viabilizar transfusões de sangue seguras. Tratou-se de um estudo transversal, descritivo e quantitativo, abrangendo o período de janeiro de 2022 a junho de 2024. A pesquisa dos AI foi realizada através da técnica de gel centrifugação (coombs indireto) e a identificação dos AI realizada através de um painel de hemácias, usando a técnica em tubos com hemácias fenotipadas. Entre os 72 pacientes incluídos, observou-se uma predominância do gênero feminino (68,06%; n=49) e da faixa etária de 61 a 80 anos (27,78%; n=20), com prevalência do grupo sanguíneo O positivo (36,12%; n=26). Quanto ao histórico transfusional, 41,7% (n=30) dos pacientes realizariam sua primeira transfusão. 45,83% (n=33) apresentaram apenas um anticorpo, enquanto 38,89% (n=28) tiveram especificidade indeterminada. Entre os anticorpos identificados (61,11%; n=44), o sistema Rh foi o mais frequente (23,61%; n=17), destacando-se o Anti-D (8,33%; n=6), enquanto a associação Anti-k + Kpb + Lub foi a mais comum (5,56%; n=4). Na categoria "1ª transfusão", os aloanticorpos indeterminados prevaleceram (39,28%; n=11), enquanto Anti-D e Anti-E apareceram em 10,71% (n=3). Em pacientes politransfundidos, o Anti-K foi mais frequente (16%; n=4). Os resultados reforçam a relevância da identificação de aloanticorpos para maior segurança transfusional, permitindo estratégias personalizadas que reduzem os riscos de aloimunização.
O ENFERMEIRO COMO PROTAGONISTA DA IDENTIFICAÇÃO PRECOCE DA SEPSE: CUIDADOS NO MANEJO E EVOLUÇÃO DO AGRAVO
Authors: Dias Bruno de Oliveira , Nogueira Elisangela Leite , Assis Tamara Quintella , Lopes William Olimpio Da Costa , Gracio Andréa Lucia Reis , Nascimento Leandro da Silva
Published: December 2024

A sepse é uma das doenças fatais mais comumente encontradas em todo o mundo. Trata-se de uma patologia que é caracterizada como uma disfunção orgânica resultante da resposta imunológica desregulada do hospedeiro à um processo infeccioso, que pode ser causado por microrganismos, com alta taxa de mortalidade. Diante disso surge o problema de pesquisa; “Qual a relevância do papel da enfermagem na identificação precoce da sepse e como intervir preventivamente?” O objetivo desse estudo foi Identificar o papel do enfermeiro na identificação precoce da sepse. Será feito um levantamento através da revisão integrativa de literatura nas bases de dados do Scientific Electronic Library Online (Scielo), Google Acadêmico e Biblioteca Virtual da Saúde. Foram utilizados 08 artigos dos anos de 2019 a 2024 que adentraram aos critérios de inclusão e objetivos do estudo relevantes à temática, sendo efetuada uma seleção de forma a utilizar aqueles que continham dados mais característicos com relação ao tema. Os resultados obtidos evidenciaram que as intervenções de enfermagem, como o uso da escala de Sofa, uso de Nanda, monitoramento dos sinais vitais, foram evidenciados como elementos chaves para a assistência de enfermagem ao paciente séptico. Ressalta-se a necessidade de atualização e qualificações para que os enfermeiros sejam capacitados. Conclui-se que é fundamental que o enfermeiro seja protagonista no manejo da sepse além  da possibilidade de criação de protocolos por parte destes profissionais, que se utilizam da sistematização da assistência de enfermagem para a identificação e prevenção de agravos, sendo essa uma forma eficaz de diminuir as complicações nos mais variados setores de atendimento em saúde
A Quantitative Analysis of the Impact of Influencer-Product Convergence and Influencer Popularity on Consumer Purchasing Behaviour
Authors: Dr. Ritika Singh
Published: December 2024

In today's marketing landscape, influencer marketing has emerged as an effective strategy for businesses. By leveraging social media and the reach of social media influencers, brands can easily advertise their products and connect with large audiences. The current generation of teenagers and young adults is highly digital-savvy and actively engages with social networks, making them the main focus for companies employing this tactic. The objective of this study is to quantitatively assess the influence of influencer-product fit and influencer popularity on consumer purchasing behavior. This research seeks to understand how well influencers align with the products they endorse and how their popularity, measured by follower count and engagement metrics, impacts consumer buying decisions. Additionally, it aims to explore the effects of this influence on consumer behavior, especially regarding purchasing decisions.
Perú se comporta como una extensión del Asia enla epidemiologia oncohematológica
Authors: Beltrán Gárate Brady
Published: December 2024

Existen mucha evidencia de alta de frecuencia de neoplasias en Perú tanigual que en el Asia , específicamente China.Para tal fin, mencionaremos 4 ejemplos, de lo anteriormente mencionado. Uno de los cánceres más frecuentes en el Perú, es el cáncer gástrico ubicado en el tercer lugar en incidencia y el primer lugar en mortalidad. En China el cáncer gástrico ocupa el quinto lugar y el tercero en mortalidad (1). En Japón, se ubica en el tercer puesto de incidencia y mortalidad. Sin embargo, en USA, elcáncer gástrico ocupa el puesto 16 en incidencia y mortalidad. Una explicaciónde ello es la alta frecuencia de infección por Helicobacter pylori en nuestro paíscomo en el Asia.
Primera cita de Orthetrum trinacria (Selys, 1841) (Odonata, Libellulidae) para la isla de Gran Canaria (España)
Authors: Martínez-Darve Sanz Pablo
Published: December 2024

First record of Orthetrum trinacria (Selys, 1841) (Odonata, Libellulidae) in Gran Canaria (Spain)
El género Armadillo Latreille, 1802 en el área ibero-balear, con la descripción de cuatro nuevas especies (Crustacea, Isopoda, Armadillidae)
Authors: Cifuentes Julio , Rando José Luis , Anguita-Erena Juan Manuel , Escarabajal-Bernabé Iván
Published: December 2024

The genus Armadillo is represented by eight species in the ibero-balear region, of which A. officinalis is a common find, while A. almerius, A. hirsutus and A. moncayotus are really scarce. The new species that are described in this work, Armadillo aguilensis n. sp., Armadillo nanii n. sp., Armadillo rinconensis n. sp. and Armadillo vinuelensis n. sp., are clearly differentiated from the aforementioned species by their lateral groove of the first pereonite and the morphology of the scale-setae that appear in the dorsal face of the integument. In this study, the male specimen of A. almerius is described for the first time and three species are referenced for the first time for some Spanish provinces. Furthermore, illustrations are provided for all the species present in the ibero-balear region, as well as a guideline to help in its identification. In addition, the stridulatory apparatus, characteristic of the Mediterranean species of this genus, is also illustrated. This apparatus is probably used in defense against predators, and in communication between the specimens of the colony.
PENGARUH INFRASTRUKTUR JALAN, INFRASTUKTUR LISTRIK DAN PERKEMBANGAN INTERNET TERHADAP PRODUK DOMESTIK REGIONAL BRUTO DI KABUPATEN SIDOARJO
Authors: Huda Syamsul , Yuliati Anik
Published: December 2024

Penelitian ini bertujuan untuk menganalisis pengaruh infrastruktur jalan, infrastruktur listrik, dan perkembangan internet terhadap Produk Domestik Regional Bruto (PDRB) di Kabupaten Sidoarjo pada periode 2019 hingga 2022. Dengan menggunakan metode regresi linier berganda, penelitian ini mengevaluasi sejauh mana masing-masing variabel independen berkontribusi terhadap pertumbuhan ekonomi regional.
Data yang digunakan mencakup panjang infrastruktur jalan (X1), persentase cakupan infrastruktur listrik (X2), dan kecepatan akses internet (X3), serta nilai PDRB (Y) Kabupaten Sidoarjo. Hasil analisis menunjukkan bahwa semua variabel independen berpengaruh positif dan signifikan terhadap PDRB. Secara khusus, peningkatan panjang jalan, kualitas pasokan listrik, dan akses internet berkecepatan tinggi berkontribusi secara signifikan terhadap pertumbuhan ekonomi daerah.
Hasil uji F menunjukkan bahwa model regresi secara keseluruhan signifikan dalam menjelaskan variasi PDRB. Uji t mengungkapkan bahwa infrastruktur jalan, infrastruktur listrik, dan perkembangan internet masing-masing memiliki pengaruh yang signifikan terhadap PDRB.
Berdasarkan temuan ini, disarankan agar pemerintah Kabupaten Sidoarjo terus meningkatkan dan memperluas investasi dalam infrastruktur jalan, listrik, dan internet. Kebijakan yang integratif dan berkelanjutan akan memastikan pertumbuhan ekonomi yang lebih inklusif dan berkelanjutan. Monitoring dan evaluasi berkala juga diperlukan untuk menilai dampak dari investasi-infrastruktur terhadap PDRB dan memastikan efektivitas kebijakan pembangunan.
Pemanfaatan Internet of Things (IoT) untuk Menjaga Kualitas Air Bersih di Desa Nongkosawit
Authors: Nugroho Agung , Kurniasari Laeli , Prianto Riska , Jati Isnanto Prasetyo , Nugroho Ardi Tio Ageng , Priangkoso Tabah
Published: December 2024

Program pengabdian masyarakat ini bertujuan untuk mengatasi permasalahan kualitas air bersih di Desa Jedung, Kecamatan Gunungpati, Kota Semarang, yang dihadapi oleh masyarakat setempat. Permasalahan utama yang diidentifikasi adalah tingginya kandungan Total Dissolved Solids (TDS), besi (Fe), mangan (Mn), serta kekeruhan air yang tidak memenuhi standar kualitas air bersih. Sebagai solusi, diterapkan sistem filtrasi berbasis Internet of Things (IoT) dan teknologi auto blowdown untuk memonitor dan mengoptimalkan kualitas air secara berkelanjutan. Kegiatan pengabdian ini dimulai dengan sosialisasi kepada masyarakat dan pengelola air, diikuti dengan survei kualitas air dan pemasangan sistem filtrasi. Hasil yang dicapai menunjukkan penurunan signifikan pada TDS, kandungan besi (Fe), mangan (Mn), dan kekeruhan, dengan peningkatan pH yang terukur pada angka 7.8 setelah penerapan sistem filtrasi. Selain itu, teknologi IoT efektif dalam memantau kinerja sistem secara real-time, memastikan sistem berfungsi secara optimal.
The Culture of Water Use in Armenia from Ancient Times to Our Days
Authors:   Institute of Archaeology and Ethnography, Bobokhyan Arsen , Hovsepyan Roman
Published: December 2024

The monograph includes results of studies in humanities and social science as well as interdisciplinary studies related to the culture of water use in Armenia, in particular, the irrigation systems, and shows the current state and the relevance of these investigations. In the presented articles, the issues related to the culture of water use are considered and discussed from the point of view of archeology, ethnography, philology, epigraphy, archaeobotany and other related disciplines, which until now were considered understudied. The articles are accompanied by descriptions and photographs of cultural landscapes, historical and cultural monuments, artifacts, cultural processes and phenomena, as well as natural environments and bioclimatic factors that have influenced the culture of water use, which further increases the value of the work.

The publication was prepared within the framework of the project "The Culture of Water Use in the Armenian Highlands from Ancient Times to the Present" (21AG-6A080) funded by the Committee of Higher Education and Science of Armenia.
The Water Use System in the Shnogh River Basin (From Ancient Times Until Our Days)
Authors:   Institute of Archaeology and Ethnography, Saratikyan Ani
Published: December 2024

The Lori region has been one of the most active economic areas of Armenia for centuries. This is evidenced by the archaeological excavations and ethnographic studies carried out there. The developed horticultural zone of the region mainly includes the basins of Debed and its tributaries. One of the big tributaries of the Debed river is Shnogh, which passes through the territories of Shnogh and Teghut villages. Our data on the water use system of this area dates back to the 3rd and 1st millennia BC, as well as to the Middle Ages and present days. The riverside horticultural slopes of the Shnogh river basin are an important evidence of the irrigation system. The intensive cultivation of these lands is evidenced by the medieval winepresses (dated from 12th to 13th centuries) documented by excavations here. Recently, due to the construction of the Teghut mining complex, the irrigation system of gardens has been disrupted. As a result of river pollution, the riverside lands are now partially irrigated by the main water pipes of the village.
On the Water System of Erebuni Fortress
Authors:   Institute of History, Badalyan Mikayel , Deschamps Stéphane ,   Ministry of Culture, France, Danielyan Henrik ,   Independent Researcher, Fichet de Clairfontaine François ,   Ministry of Culture, France
Published: December 2024

Urartu (Biaina, Kingdom of Ararat, Kingdom of Van) is considered to have had one of the most developed irrigation systems among powers in the Ancient Near East. Many cuneiform inscriptions left by the monarchs of the Ararat Kingdom mention the construction of canals, artificial lakes, cisterns etc. To date, important investigations have been carried out in the study of Urartian canals, artificial lakes, and dams. However, there is a lack of research on the water systems (supply or sewage) in the Urartian fortresses themselves. In this context, the excavations carried out in the Altıntepe Urartian fortress near the city of Yerznka in Historical Armenia provide relevant data. A very similar “aqueduct’’ system was also unearthed in Erebuni fortress, Yerevan, Republic of Armenia. The discovery of fixed water systems in Altıntepe and Erebuni allows us to assert the presence of a highly developed water supply or sewage system in Urartu. Apparently, such “water canals” were built after the planning of the fortresses in the preliminary phase and were mainly underground. It is possible that the “water canals” had a drainage or sewage function. However, it should not be excluded that at least a part of them was used for water supply. In our opinion, the provision of a water supply to Urartian fortresses built on high hills could be implemented using highly developed engineering knowledge and systems, such as, for example, the qanat system. It is interesting that the traditions and use of those Urartian systems continued also in the Middle Ages of Armenia.
Water Reservoirs of Medieval Fortresses
Authors:   “Service for The Protection of Historical Environment and Cultural Museum-reservations” SNCO, Mkrtchyan Levon , Sargsyan Gagik ,   Institute of Archaeology and Ethnography
Published: December 2024

This article is dedicated to the water reservoirs of the High Middle Age fortresses of Armenia, which are located outside the walls and are examples of civil architecture of the given period.

Ancient and Early Medieval fortresses were usually built near water outlets (rivers, lakes or springs), from which water was brought to the fortress through pipes or culverts. However, the situation changed when in the High Middle Ages, with the deepening feudal fragmentation, the fortresses began to be located in the most isolated and inaccessible places, which soon led to the problem of water supply. Being built on the tops of rocky hills, it was even a problem to dig a deep well. Although some of the hills with fortresses were located near water sources, it was very necessary to store water for a long siege.

Since the 10th century, buildings called “water reservoirs” appeared in fortresses. These buildings are made of stone or are rock-cut, the interior of which is plastered to ensure water resistance.

Thus, we are dealing with a very important monument of medieval Armenia, which can actually become not only an architectural, but also a rich engineering and technical source for specialists investigating this period. Therefore, giving these structures the status of a separate monument or sub-monument becomes a priority. Due to it, by separating a special category of “fortress”, a new unit of Armenian civil monument will be added. In this regard, the works carried out by our team using modern methods (modeling, GIS) within the framework of the “Study of Syunik and Artsakh Fortresses” program, are of particular importance. As a result, nearly two dozen fortresses were attested.
New Discoveries Intowards the Water Use Systems of the Medieval Baths of the Lore Berd Fortress
Authors:   "Scientific Research Center of Historical and Cultural Heritage" SNCO, Nalbandyan Arman
Published: December 2024

The fortress Lore Berd, located in the Lori Berd community of the Lori Province of the Republic of Armenia, is one of the best preserved fortresses in Armenia. This famous fortress of historical Gugark region arose on a high cape formed at the intersection of gorges where the rivers Dzoraget (Tashrajur) and Urut (Miskhana) merge. It is located at an altitude of 1490 m above sea level and together with the suburbs occupies an area of 50–60 hectares (only the citadel takes up 9 hectares). Based on archaeological excavations carried out both in the Soviet Union period and in the 2000s, the cultural image of this famous fortress was revealed.

Excavations of the Lore Berd Fortress resumed in 2022, under a special grant from the RA MoESCS, within the framework of the restoration and development project, the archaeological expedition of the Scientific Research Center of Historical and Cultural Heritage (expedition leader: A. Nalbandyan, archaeologist: M. Khechoyan, assistant: S. Bislamyan). The work was carried out at several sites. They, revealed significant results both in terms of architecture and studying of cultural layers.

Particularly noteworthy are the results of excavations in two baths of the Lore Berd Fortress. The studied lower, earliest layers gave not only a huge number of findings of material culture (ordinary, red-polished, stamped and glazed ceramics, glass bracelets and beads, smoking pipes, coins, various copper objects, etc.), but also led to remarkable discoveries concerning the water supply of baths, the movement/circulation of water and, the floor heating systems. The discovered pools, ditches, clay water pipes and water taps further enriched our understanding of the engineering system of the bathhouses of Lore Berd Fortress.
On The Prehistoric Irrigated and Rain-Fed Agricultural Systems in the Territory of Armenia (According to Archaeobotanical Studies)
Authors:   Institute of Archaeology and Ethnography, Hovsepyan Roman
Published: December 2024

Agriculture in the territory of the Republic of Armenia was established about eight thousand years ago, in the Ararat Valley, and was irrigated. About five and a half thousand years ago, because of the global climate changes, in particular, the aridification of the climate and the reduction of water resources in lowlands, there were still sufficient water resources for agriculture in the mountains (rain, ice and snow accumulations, springs fed from them, etc.). As a result, starting from the Early Bronze Age, local communities began to engage in rainfed agriculture in the hard-to-reach and hard-to-cultivate mountainous lands. From the Early Bronze Age to the Early Iron Age, the main or only direction of agriculture in the region was the cultivation of cereals.

This was most probably due to climate aridification, which was the original and main cause of this phenomenon: irrigation is essential to agriculture in the dry lowlands, while some hardy crops in the mountains can be cultivated without water, relying only on rain. It is noteworthy that the “specialization” of agriculture in cereals cultivation was the same both in the mountains and in the lowlands. It is possible that the access to water gave the communities living in the mountains an environmental and economic advantage, which was the reason for the spread and strengthening of their forms of production, primarily - agricultural traditions, in the communities living in the lowlands.
Estrategia innovadora para fomentar la lectura en estudiantes de educación general básica
Authors: Zapata William , Pazmiño Medina Diana del Rosario
Published: December 2024

Desde tiempos remotos, es decir, desde la aparición de la escritura,  la lectura ha desempeñado un papel muy importante en la formación integral de las personas, contribuyendo significativamente al desarrollo y progreso de las sociedades.  El presente estudio tiene un enfoque positivista de carácter cuantitativo, su objetivo es elaborar un folleto de lectura  como una estrategia didáctica  para optimizar  la comprensión lectora en los educandos de educación general  básica. La población que formó parte del estudio está integrada por 80 estudiantes de quinto año de educación general básica media de la Unidad Educativa “Atahualpa” de la ciudad de Ambato.  El diseño de este estudio es cuasi experimental con pre test y post test. Las técnicas de recolección de información a emplearse son una evaluación de base estructurada de 10 preguntas tanto para el pre test como para  el post test, tres talleres de manera individual y tres de forma  grupal, cada taller cuenta con un  test de evaluación de 5 preguntas de opción múltiple. Los resultados demuestran que los estudiantes quienes usaron el folleto de lectura tienen mejores resultados en su rendimiento académico que aquellos sometidos a clases tradicionales. En conclusión los docentes deben integrar estrategias innovadoras para motivar el hábito de la lectura y optimizar la comprensión lectora en los educandos.
Review on Synergistic Effects of Probiotics, Prebiotics, and Synbiotics on Gut Microbiota Homeostasis
Authors: Ghulam Murtaza  , Zaighum Abbas  , Sabeen Gul  , Asfa Karam  , Nadia Cheema  , Maham Zahra  , Sarwat Abbas  , Fazil Ali  , Abdul Kabir  , Muhammad Kamal Shah  , Muhammad Sajid
Published: December 2024

Functional foods are an essential part of the contemporary diets, and it is evident that these foods contain the health benefits in addition to the familiar nutritional effects. Probiotics and prebiotics together is referred to as synbiotics and are presently the most popular functional food ingredients. The most commonly used probiotic strains are Lactobacilli, Bifidobacterium, S. boulardii and B. coagulans. Some of the most used fibers are galacto-oligosaccharides (GOS), fructo-oligosaccharides (FOS), xylose-oligosaccharide (XOS), inulin, and fructans when blended with probiotics are referred to as synbiotics and are efficient in provoking the growth of the bacteria.