bluuebunny/crossref_metadata_2025 huggingface dataset:
Objective and Subjective Appetite Assessment in Patients with Gynecological Cancer: A Pre- and Post-Operative Pilot Study
Authors: Gounitsioti Iro-Spyridoula , Poulimeneas Dimitrios , Grammatikopoulou Maria G. , Kotzamanidis Charalambos , Gkiouras Konstantinos , Nigdelis Meletios P. , Tsolakidis Dimitrios , Papanikolaou Alexios , Tarlatzis Basil C. , Bogdanos Dimitrios P. , Tsigga Maria , Goulis Dimitrios G.
Published: August 2022

Although appetite and its disorders have been implicated in disease progression and outcomes, ghrelin concentrations, an objective appetite measure, are rarely assessed in patients with gynecological malignancies. The present study aimed to assess changes in post-operative versus pre-operative appetite levels in patients with gynecological cancers scheduled for tumor removal surgery (N = 53). Acylated ghrelin concentrations were assessed as an objective appetite proxy, whereas the Council of Nutrition appetite questionnaire (CNAQ) was employed as a subjective appetite measure. Ghrelin concentrations were increased post-operatively (median: 12.1 pg/mL, IQR: 0.67 to 23.5, p-value = 0.001) but the perceived appetite of patients (CNAQ) remained unchanged (median: −1, IQR: −3 to 1). Tumor removal surgery decreased all anthropometric indices (body weight, body mass index, waist and hips circumferences, triceps skinfolds, body fat, fat mass and fat mass index, p-value ≤ 0.001 for all) and doubled the risk of malnutrition among patients. No difference was recorded in the change in participants’ objective and subjective appetite when they were classified according to the tumor type. No correlation was observed between ghrelin concentrations and CNAQ score pre-operatively (Spearman’s rho correlation coefficient = −0.181, p-value = 0.298) or post-operatively (Spearman’s rho correlation coefficient = 0.071, p-value = 0.684). The observed post-operative rise in ghrelin concentrations is associated with body weight loss and consists of a possible defense mechanism of the human body, aiming to prolong survival.
Mentalization and Its Relation to Life Satisfaction and the Level of Mental Adjustment to Illness in Women with Breast Cancer—A Pilot Study
Authors: Cieślak Mariusz , Kozaka Joanna , Golińska Paulina Beata , Bidzan Mariola
Published: August 2022

This study’s aim was assessing of the relationship between mentalization and life satisfaction and the level of adaptation to oncological disease in patients with breast cancer. The study involved 41 women (M = 59.88; SD = 8.81) with breast cancer who completed their treatments and participated in a cancer rehabilitation program. In the study, we used the Mentalization Questionnaire (MZQ), the Satisfaction Life Scale (SWLS), and the Mini-Mental Adjustment to Cancer Scale (Mini-MAC). The mean of declared level of mentalization was 45.54 (SD = 11.65). The significant correlation between mentalization (its general value and individual dimensions) and satisfaction with life/mental adjustment to cancer was observed. The strongest positive correlations were noted between refusing self-reflection, helplessness–hopelessness, and anxious preoccupation and the negative correlation between mentalization and satisfaction with life. Mentalization was a predictor of satisfaction with life and mental adjustment to illness. Mentalization was related with life satisfaction and adjustment to cancer in patients with breast cancer, which is in line with previous studies suggesting the crucial role of subjective psychological factors in maintaining mental health.
Physical Performance Tests in Adult Neck Pain Patients with and without Clinical Myelopathic Signs: A Matched Case-Control Study
Authors: Lwin Mon Mon Hnin , Puntumetakul Rungthip , Sae-Jung Surachai , Tapanya Weerasak , Chatchawan Uraiwan , Chatprem Thiwaphon
Published: August 2022

Patients with neck pain may experience cervical myelopathy, this may be detected by clinical myelopathic signs, although they did not have any symptom of myelopathy, except having neck pain. Decreasing physical performance is one symptom of cervical myelopathy that can lead to reduced quality of life in the elderly, however, in adult neck pain with clinical myelopathic signs have not been evaluated. Therefore, this research aimed to compare physical performance in two groups of adult patients with neck pain: those with and without clinical myelopathic signs. A total of 52 participants, gender, age, and body mass index (BMI) matched were allocated into 2 groups of 26 subjects with neck pain, those with, and without, clinical myelopathic signs. The grip and release test, nine-hole peg test, ten second step test and foot-tapping test were evaluated. The group of neck pain participants with clinical myelopathic signs exhibited greater impairment in all the tests than the group without clinical myelopathic signs (p < 0.001). Effect sizes (Cohen’s d) were grip and release test: 2.031, nine-hole peg test: 1.143, ten second step test: 1.329, and foot-tapping test: 0.798. Neck pain participants with clinical myelopathic signs demonstrated reduced physical performance. Physical performance tests may need to assessed in adult patients with neck pain who had clinical myelopathic signs.
Traffic Risk Environment Impact Analysis and Complexity Assessment of Autonomous Vehicles Based on the Potential Field Method
Authors: Cheng Ying , Liu Zhen , Gao Li , Zhao Yanan , Gao Tingting
Published: August 2022

Although autonomous vehicles have introduced a promising potential for improving traffic safety and efficiency, ensuring the safety of autonomous vehicles in complex road traffic environments is still a huge challenge to be tackled. To quickly quantify the potential risk factors of autonomous vehicles in traffic environments, this paper focuses mainly on the influence of the depth and breadth of the environment elements on the autonomous driving system, uses the potential field theory to establish a model of the impact of the environmental elements on the autonomous driving system, and combines AHP to quantify equivalent virtual electric quantity of each environment element, so as to realize the quantitative evaluation of the traffic environment complexity. The proposed method comprehensively considers the physical attributes and state parameters of the environmental elements, which compensates for the fact that the shortage of the factors considered in the traffic environment complexity assessment is not comprehensive. Finally, a series of experiments was carried out to verify the reliability of our proposed method. The results show that the complexity of the static elements is determined only by the physical attributes and shape of the obstacle; the complexity of the dynamic elements is determined by the movement of the obstacle and the movement of the autonomous vehicle, and the comprehensive complexity mainly depends on the complexity of their dynamic elements. Compared with other methods, the complexity evaluation values are generally consistent, the absolute percentage error of the majority of samples was within ±5%, and the degree of deviation was −1.143%, which provides theoretical support for autonomous vehicles on safety and the risk assessment in future.
How Does a Healthy Interactive Environment Sustain Foreign Language Development? An Ecocontextualized Approach
Authors: Xiao Hao-Zhang
Published: August 2022

Recent inconsistent empirical findings on the impact of context on foreign language development (FLD) are related to some conflicting context views, which hinders healthy FLD. Given this, an ecocontextualized approach/perspective is presented as a ”recipe”, holding that inter-intrastratally interactive context-oriented learning starts with the alignment of implicit sound-meaning mapping (phonic listening and speaking only) with the low cognitive levels of early starters and physical objects/visual realia in the proximate context, and only when the learners’ cognitive levels develop several years later can it turn to explicit formal learning through abstract written language and contents. Based on this view, a sound-meaning mapping prioritizing (SMMP) route to healthy/sustainable FLD is proposed and testified via questionnaires and an interview/oral test. Results showed: (1) SMMP early starters surpassed the non-SMMP (NSMMP) early starters (learning reading, listening, speaking, and writing simultaneously) in oral proficiency at the late stage despite their homogeneity at the early stage; (2) oral, especially listening abilities, could not be well developed at the late stage by NSMMP learners; (3) written proficiency could be developed later by both types. These findings reveal the SMMP route to healthy/sustainable FLD in the Chinese context.
Changes in Certitude, Adherence, and Attitude: Immediate Effects of Rape Myth Intervention on Jurors in a Mock Trial
Authors: Pang Yazhi , Davies Kari , Liu Yong
Published: August 2022

Previous studies have demonstrated the prevalence and negative consequences of rape myths in various social contexts, including their impact on jury decision-making. The current study adopted a mixed methods design to explore how educating jurors about rape myths via a judge’s direction affected their decision-making regarding the guilt or innocence of a defendant in a rape case. Data were obtained from two mock trials and 12 questionnaire responses. The sample consisted of 12 women participants aged from 20 to 25. The thematic analysis indicated that participants who received rape myths education exhibited resistance to rape myths, increased scrutiny of the defendant as opposed to the complainant, and less disbelief of the complainant’s alleged behaviours. Quantitative analysis suggested a strong positive correlation between the understanding of rape myths education and its influence on decision making; however, this was only found in the intervention group. Findings showed insights into the possible advantages of rape myths education for jurors that were delivered via the judge’s direction. Future research directions and implications were discussed.
The Association between Coparenting Behavior and Internalizing/Externalizing Problems of Children and Adolescents: A Meta-Analysis
Authors: Zhao Fengqing , Wu Haomeng , Li Yixuan , Zhang Huifang , Hou Jie
Published: August 2022

This study aimed to determine the association between coparenting behavior and children’s externalizing and internalizing problems and possible factors that may moderate their associations. A meta-analysis of 93 studies involving 41,207 participants found that coparenting behavior was slightly and significantly related to externalizing problems, r = −0.17, 95% CI [−0.194, −0.15], and internalizing problems, r = −0.16, 95% CI [−0.18, −0.14]. In addition, coparenting integrity, cooperation, conflict, competitiveness, and triangulation were significantly related to externalizing and internalizing problems. Moderation analyses revealed the following findings: (a) data reporter moderated the association between coparenting and internalizing problems, with children-report coparenting showing a significantly stronger relation with internalizing symptom than father-report coparenting; (b) developmental stage was found to moderate the association between coparenting behavior and externalizing problems, with stronger association found in childhood than in toddlerhood; (c) female percentage, individualism–collectivism culture, research methods, and publication year were not found to moderate the association between coparenting behavior and externalizing or internalizing problems. These findings help summarize the previous studies and provide an empirical basis for the relation between coparenting and child externalizing/internalizing problems, and benefits targeted interventions towards coparenting behaviors.
Leveraging Reddit for Suicidal Ideation Detection: A Review of Machine Learning and Natural Language Processing Techniques
Authors: Yeskuatov Eldar , Chua Sook-Ling , Foo Lee Kien
Published: August 2022

Suicide is a major public-health problem that exists in virtually every part of the world. Hundreds of thousands of people commit suicide every year. The early detection of suicidal ideation is critical for suicide prevention. However, there are challenges associated with conventional suicide-risk screening methods. At the same time, individuals contemplating suicide are increasingly turning to social media and online forums, such as Reddit, to express their feelings and share their struggles with suicidal thoughts. This prompted research that applies machine learning and natural language processing techniques to detect suicidality among social media and forum users. The objective of this paper is to investigate methods employed to detect suicidal ideations on the Reddit forum. To achieve this objective, we conducted a literature review of the recent articles detailing machine learning and natural language processing techniques applied to Reddit data to detect the presence of suicidal ideations. Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, we selected 26 recent studies, published between 2018 and 2022. The findings of the review outline the prevalent methods of data collection, data annotation, data preprocessing, feature engineering, model development, and evaluation. Furthermore, we present several Reddit-based datasets utilized to construct suicidal ideation detection models. Finally, we conclude by discussing the current limitations and future directions in the research of suicidal ideation detection.
Exercise to Improve Postural Stability in Older Adults with Alzheimer’s Disease: A Systematic Review of Randomized Control Trials
Authors: Adzhar Mohamad Asyraf , Manlapaz Donald , Singh Devinder Kaur Ajit , Mesbah Normala
Published: August 2022

In this systematic review, we aim to synthesize published evidence on the effects of exercise in improving postural stability among older adults with Alzheimer’s Disease (AD). A systematic electronic literature search was undertaken in Pedro, Cochrane, MEDLINE, ProQuest, Science direct and Clinical trial databases involving human participants published from year 2000–2022. This search was updated in June 2022. The studies chosen were based on predetermined criteria. Data relating to the contents and parameters of exercise in persons with AD were gathered and analyzed. A total of 8 experimental studies met the inclusion criteria. Overall, the selected studies were of a medium quality. In these studies, information and physical exercises were used to improve postural stability in older adults with AD. The findings of the review suggest that performing combined strength, balance and executive function training can improve postural stability. However, we are unable to conclude the specific dose for specific type of exercise. More high-quality studies are required pertaining to exercise prescription for older adults with AD. Mostly, information and physical exercise were delivered via face-to-face sessions conducted by health professionals. The structure of exercises summarized in this review may be beneficial for older adults with AD to improve postural stability and as a result reduce falls.
Benzene and NO2 Exposure during Pregnancy and Preterm Birth in Two Philadelphia Hospitals, 2013–2017
Authors: Escoto Kathleen M. , Mullin Anne M. , Ledyard Rachel , Rovit Elizabeth , Yang Nancy , Tripathy Sheila , Burris Heather H. , Clougherty Jane E.
Published: August 2022

Infants born preterm are at risk of neonatal morbidity and mortality. Preterm birth (PTB) can be categorized as either spontaneous (sPTB) or medically indicated (mPTB), resulting from distinct pathophysiologic processes such as preterm labor or preeclampsia, respectively. A growing body of literature has demonstrated the impacts of nitrogen dioxide (NO2) and benzene exposure on PTB, though few studies have investigated how these associations may differ by PTB subtype. We investigated the associations of NO2 and benzene exposure with sPTB and mPTB among 18,616 singleton live births at two Philadelphia hospitals between 2013 and 2017. Residential NO2 exposure was estimated using a land use regression model and averaged over the patient’s full pregnancy. Benzene exposure was estimated at the census tract level using National Air Toxics Assessment (NATA) exposure data from 2014. We used logistic mixed-effects models to calculate odds ratios for overall PTB, sPTB, and mPTB separately, adjusting for patient- and tract-level confounders. Given the known racial segregation and PTB disparities in Philadelphia, we also examined race-stratified models. Counter to the hypothesis, neither NO2 nor benzene exposure differed by race, and neither were significantly associated with PTB or PTB subtypes. As such, these pollutants do not appear to explain the racial disparities in PTB in this setting.
Rare Diseases: Needs and Impact for Patients and Families: A Cross-Sectional Study in the Valencian Region, Spain
Authors: Gimenez-Lozano Cristina , Páramo-Rodríguez Lucía , Cavero-Carbonell Clara , Corpas-Burgos Francisca , López-Maside Aurora , Guardiola-Vilarroig Sandra , Zurriaga Oscar
Published: August 2022

Families with rare diseases (RDs) have unmet needs that are often overlooked by health professionals. Describing these needs and the impact of the disease could improve their medical care. A total of 163 surveys were obtained from patients visiting primary care centres in the Valencian Region (Spain), during 2015–2017, with a confirmed or suspected diagnosis of RD. Of the 84.7% with a confirmed diagnosis, 50.4% had a diagnostic delay exceeding one year, and it was more prevalent among adults (62.2%). Families with paediatric patients were in a worse economic situation, with lower incomes and higher monthly disease-related expenses (€300 on average). These expenses were incurred by 66.5% of families and were mainly for medication (40.3%). Among them, 58.5% reported not being able to afford adjuvant therapies. The disease had an impact on 73.1% of families, especially on their routine and emotional state. Expenses, needs, and impacts were more frequent among families of patients with a history of hospitalisation or deterioration. Patients with delayed diagnosis had a higher consumption of drugs prior to diagnosis. People affected by RDs in the Valencian Region need therapies to improve their autonomy and emotional state. Health professionals should be aware of these needs.
Dose–Response Relationship of Resistance Training on Metabolic Phenotypes, Body Composition and Lipid Profile in Menopausal Women
Authors: Magalhães Ana Carla Leocadio de , Carvalho Vilma Fernandes , Cruz Sabrina Pereira da , Ramalho Andrea
Published: August 2022

The relationship between volume training of resistance training (RT), body composition and cardiometabolic profile in menopausal women is poorly understand. This study aimed to evaluate the dose–response relationship of RT on lipid profile, body composition and metabolic phenotypes in menopausal women. A total of 31 women were categorized according to different volume of RT. Body composition was evaluated by DEXA and the cardiometabolic risk by metabolic phenotypes and lipid profile. There was a higher frequency of metabolically unhealthy phenotype in women who practiced RT for less than two years and had a weekly frequency lower than three days a week (p > 0.05). Women with more than two years and a higher weekly frequency of RT had lower trunk fat mass than their counterparties (15.33 ± 7.56 versus 10.57 ± 4.87, p = 0.04; 16.31 ± 7.46 versus 10.98 ± 5.49, p = 0.03, respectively). There was an association between HDL-c and time of RT in years. A moderate correlation was identified between variables of body adiposity, time in years and weekly frequency of RT. The present study concludes that more time in years and weekly frequency of RT practice are associated with lower body adiposity in menopausal women, the first also being associated with HDL-c.
Spatio-Temporal Variation and Influencing Factors of the Coupling Coordination Degree of Production-Living-Ecological Space in China
Authors: Cui Xinghua , Xu Ning , Chen Wanxu , Wang Guanzheng , Liang Jiale , Pan Sipei , Duan Binqiao
Published: August 2022

Territorial space is a multi-functional complex. The coordinated production-living-ecological space (PLES) effectively coordinates the man-land relationship, promotes regional sustainable development, and maximizes territorial space. How to build a high-quality national spatial layout and support system for development has become a hot topic of concern in all sectors of society. However, few studies have explored the coupling coordination considering the various production-living-ecological functions of land use type and its influencing factors of PLES at the county scale in China. To address the gap, based on the connotation of PLES theory, this study established a classification and evaluation system for PLES and analyzed the spatio-temporal characteristics, coupling coordination degree, spatial autocorrelation, and influencing factors of PLES in China from 2000 to 2020. The results are as follows: (1) The production space index and living space index in China showed a continuous increase tendency, while the ecological space index decreased continuously during the study period. The production space and living space were concentrated in the east of Hu Line, and the ecological space indexes in mountainous areas were significantly higher than those in plain areas during the study period. (2) The gravity centers of PLES all migrated to the west of China to different degrees during the study period. (3) From 2000 to 2020, the basically balanced category was the main coupling coordination type, and the number of seriously unbalanced categories accounted for the least. In the west of the Hu Line, the seriously unbalanced category was dominant, while in the east of the Hu Line were the moderately unbalanced categories and above. (4) During the study period, the low-low type was the main relationship type, widely distributed in western China, followed by the high-high type, mainly situated in the North China Plain, Yangtze River Delta, Pearl River Delta, Jianghan Plain, Chengdu Plain, Northeast China Plain, and some provincial capital cities. (5) Regression results showed that natural factors were the main reason restricting the coordinated development of PLES, and socioeconomic factors could effectively promote the coordinated development of PLES. Landscape pattern also significantly influenced the coordinated development of PLES, but varied greatly. The findings of this study can provide a scientific reference for the optimization of territorial space layout and the promotion of high-quality development of territorial space.
Multilayer Perceptron-Based Real-Time Intradialytic Hypotension Prediction Using Patient Baseline Information and Heart-Rate Variation
Authors: Bae Tae Wuk , Kim Min Seong , Park Jong Won , Kwon Kee Koo , Kim Kyu Hyung
Published: August 2022

Intradialytic hypotension (IDH) is a common side effect that occurs during hemodialysis and poses a great risk for dialysis patients. Many studies have been conducted so far to predict IDH, but most of these could not be applied in real-time because they used only underlying patient information or static patient disease information. In this study, we propose a multilayer perceptron (MP)-based IDH prediction model using heart rate (HR) information corresponding to time-series information and static data of patients. This study aimed to validate whether HR differences and HR slope information affect real-time IDH prediction in patients undergoing hemodialysis. Clinical data were collected from 80 hemodialysis patients from 9 September to 17 October 2020, in the artificial kidney room at Yeungnam University Medical Center (YUMC), Daegu, South Korea. The patients typically underwent hemodialysis 12 times during this period, 1 to 2 h per session. Therefore, the HR difference and HR slope information within up to 1 h before IDH occurrence were used as time-series input data for the MP model. Among the MP models using the number and data length of different hidden layers, the model using 60 min of data before the occurrence of two layers and IDH showed maximum performance, with an accuracy of 81.5%, a true positive rate of 73.8%, and positive predictive value of 87.3%. This study aimed to predict IDH in real-time by continuously supplying HR information to MP models along with static data such as age, diabetes, hypertension, and ultrafiltration. The current MP model was implemented using relatively limited parameters; however, its performance may be further improved by adding additional parameters in the future, further enabling real-time IDH prediction to play a supporting role for medical staff.
Causal Model Analysis of Police Officers’ COVID-19 Fear, Resistance to Organizational Change Effect on Emotional Exhaustion and Insomnia
Authors: Hung Wen-Ling , Liu Hsiang-Te
Published: August 2022

Since the end of 2019, COVID-19 has continued to spread around the world. The police have performed various epidemic prevention and routine duties. This study explores how police officers’ COVID-19 fear, resistance to organizational change, intolerance of uncertainty, and secondary trauma affect emotional exhaustion and insomnia in the context of COVID-19. A total of 205 valid police samples were collected in this study, and the established hypotheses were tested using confirmatory factor analysis and structural equation modeling. The results of the study confirmed that during the COVID-19 outbreak, secondary trauma of police officers positively affects emotional exhaustion and insomnia; intolerance of uncertainty positively affects emotional exhaustion; resistance to organizational change positively affects intolerance of uncertainty and emotional exhaustion; intolerance of uncertainty mediates the relationship between resistance to organizational change and emotional exhaustion; COVID-19 fear positively influences secondary trauma.
Spatio-Temporal Characteristics of Water Ecological Footprint and Countermeasures for Water Sustainability in Japan
Authors: Su Yin , Zheng Qifang , Liao Shenghai
Published: August 2022

Water-related problems are mostly caused by water imbalances between supply and demand. This study adopts the ecological footprint method to conduct an empirical study on the sustainable utilization of water resources in Japan. According to the basic principles and calculation methods of water ecological footprint (WEF), the characteristics of Japan’s water ecological footprint were investigated from the time and space dimensions, and a comparative analysis was made with the water ecological footprint of China. The results show that: from 1980 to 2020, the total water ecological footprint in Japan showed a downward trend in both the traditional account and pollutant account, and its spatial pattern was characterized by the relation that the higher the urbanization rate, the larger the water ecological footprint. In terms of water ecological footprint efficiency, Japan’s agricultural water ecological footprint efficiency was the lowest, and the domestic water ecological footprint efficiency was the highest. The water resources policies and measures that Japan and other developing countries should take to ensure the sustainability of water resources were analyzed separately.
A Two-Week Vacation in the Tropics and Psychological Well-Being—An Observational Follow-Up Study
Authors: Laukkala Tanja , Rosenström Tom , Kantele Anu
Published: August 2022

Despite the vast annual number of international visitors to the tropics, surprisingly little data are available on the psychological well-being associated with the travels or with travelers’ diarrhoea (TD). We herein recruited participants of a vaccination trial, OEV-123, before their 12-day holiday in Benin, West Africa. We assessed the travelers’ psychological distress with a general health questionnaire (GHQ-12) and retrieved data on TD from the trial database. The GHQ-12 was completed before (wave 0), at return (wave 1), and 1-month after (wave 2) the trip. Of the 174 participants, 73% were women, with a mean age 40 years. Moreover, 24% reported psychological distress before traveling, 10% immediately after, and 16% 1-month after the trip (GHQ-12, 3 or more; 0–12 scoring). The findings showed that psychological well-being increased after the tropical holiday. The GHQ-12 middle wave sum score differed from the wave 0 (p < 0.001) and wave 2 (p = 0.008) sum scores, with travelers reporting highest levels of well-being on their return, with evidence of a lasting improvement. TD was experienced by 71%, and it had a negative impact on psychological well-being only if experienced after travel.
The Role of Context in Integrating Buprenorphine into a Drop-In Center in Kampala, Uganda, Using the Consolidated Framework for Implementation Research
Authors: Dickson-Gomez Julia , Krechel Sarah , Katende Dan , Johnston Bryan , Twaibu Wamala , Glasman Laura , Ogwal Moses , Musinguzi Geofrey
Published: August 2022

Background: Although Africa has long borne the brunt of the human immunodeficiency virus (HIV) epidemic, until recently, the continent has been considered largely free of illicit drug use and injection drug use in particular. In Uganda, the number of people who use or inject drugs (PWUD and PWID, respectively) has increased, and PWID are a key population at high risk for human immunodeficiency virus (HIV) and hepatitis C virus (HCV) infection. However, harm reduction practices, including providing clean injection equipment and medication-assisted treatment (MAT), have only recently been piloted in the country. This project aims to integrate buprenorphine into a harm reduction drop-in center (DIC). Methods: The Consolidated Framework for Implementation Research was used to guide our preparations to integrate buprenorphine into existing practices at a harm reduction DIC. We conducted key informant interviews with members of a community advisory board and DIC staff to document this process, its successes, and its failures. Results: Results indicate that criminalization of drug use and stigmatization of PWUD challenged efforts to provide buprenorphine treatment in less regulated community settings. Conclusions: DIC staff and their commitment to harm reduction and advocacy facilitated the process of obtaining necessary approvals.
Pakistani Women: Promoting Agents of Healthy Eating Habits in Catalonia—Protocol of a Culturally and Linguistically Appropriate Randomized Control Trial (RCT) Based on the Transtheoretical Model
Authors: Mohamed-Bibi Saba , Contreras-Hernández Jesús , Vaqué-Crusellas Cristina
Published: August 2022

(1) Introduction: Dietary and lifestyle changes along with the cultural and linguistic barriers convert the immigrant women of Pakistani origin into a risk population for developing metabolic syndrome (MetS) and cardiovascular diseases (CVD). The objective of this project is to evaluate the efficacy of a culturally and linguistically appropriate food education program based on the Transtheoretical model that will allow the participants to become ambassadors of healthy eating habits for their community. (2) Methods: In this community-based RCT, any Pakistani adult woman with residence in Badalona and Santa Coloma de Gramenet will be able to participate. We will use a mixed model approach. From the quantitative perspective, the participants will answer a survey accompanied by a multilingual nutritionist that will help us to determine the sociodemographic, clinical, anthropometric, dietary data, and quality of life. From the qualitative perspective, we will conduct 6 focus groups (3 in each municipality) to determine the cultural and religious beliefs with the aim of tailoring the intervention to the target population. Hereafter, the participants from one municipality will randomly become the control group and from the other, the intervention group. The intervention group will participate in 10 weekly food education sessions based on the Transtheoretical model while the control group will receive 3 general educational sessions on food and health. During the evaluation procedure, we will assess the impact of the intervention considering the outcomes of the study. (3) Discussion: This study will establish intercultural bridges between health professionals and the Pakistani community living in Catalonia. The project will open the door for future interventions, and it will be sustainable in time as the participating women will become health promotion agents for the rest of their community.
Nicotine Dependence and the Level of Motivation for Ceasing Smoking in the Case of Patients Undergoing Vascular Surgeries Versus the Optimisation of Perioperative Care—Pilot Survey
Authors: Piotrkowska Renata , Mędrzycka-Dąbrowska Wioletta , Jarzynkowski Piotr , Ślusarz Robert
Published: August 2022

Introduction: Smoking is one of key risk factors of cardiovascular diseases, including abdominal aortic aneurysm (AAA), peripheral arterial disease (PAD), and carotid artery disease (CAD). Despite attempts being made to make the society aware of the consequences of passive and active smoking, as well as worldwide and nationwide epidemiologic research reflecting the scale of the problem, there are still a lot of smokers. Aim: The purpose of the study was to assess the relationship between the degree of addiction and the level of motivation for ceasing smoking in the case of patients before vascular surgery. Furthermore, to point out factors that have a significant impact on the level of nicotine dependence and motivation for ceasing smoking. Methods: The survey included patients qualified for vascular surgeries. The patients were active smokers: 69.3% men and 30.7% women. The survey was conducted in the form of a questionnaire based on standard research tools: the Fagerström Test for Nicotine Dependence (FTND), the Test of Motivation for Ceasing Smoking by Nina Schneider, and the original questionnaire aimed at collecting social and demographic data. Results: Most patients showed a high or moderate degree of nicotine dependence: 46.5% and 40.6%, respectively. An average nicotine dependence ratio based on the Fagerström test was 6.23 ± 2.39. An average motivation for the ceasing smoking ratio was 4.88 ± 2.76. Only 34.7% of the patients had a high motivation for ceasing smoking. Over half of the patients (61.4%) attempted to cease smoking in the past. Conclusions: Most patients undergoing vascular surgeries showed a high or moderate degree of nicotine dependence and low motivation to quit smoking. The greater the addiction to nicotine, the lower the motivation to quit smoking. Social and demographic factors do not affect the degree of nicotine addiction and the motivation to quit smoking. Years of smoking had an impact on the incidence of chronic obstructive pulmonary disease (COPD).
Physical Education Classes and Responsibility: The Importance of Being Responsible in Motivational and Psychosocial Variables
Authors: Manzano-Sánchez David
Published: August 2022

The objective of this research work was to analyse the different profiles that can be identified, based on levels of responsibility in relation to Self-Determination Theory, school climate and violence in Physical Education classes. For this, a total of 470 students of Compulsory Secondary Education or Baccalaureate were given a questionnaire where aspects related to motivation, basic psychological needs, responsibility, school social climate and violence were analysed. An analysis of these profiles was conducted, taking into account the variables of “personal responsibility” and “social responsibility”, with the results leading to the conclusion that three profiles exist: “low responsibility” (n = 89), “moderate responsibility” (n = 187) and “high responsibility” (n = 194). The results reflected statistically significant differences in all the variables between the three profiles. The high responsibility cluster obtained significantly higher values for the different constructs of motivation (except in external regulation, where there were no differences, compared to the “moderate responsibility” group), basic psychological needs and school social climate. On the other hand, it obtained lower values in amotivation and violence, with no differences based on the sex or age of the participants in the distribution of the clusters. It is concluded that the more responsible profile can have positive results in psychological variables in Physical Education classes and in the general educational field. For this reason, the use of active methodologies, which have been extensively studied to promote responsibility in PE classes, could be an appropriate strategy to achieve a more adaptive psychological profile regardless of the gender or age of the students.
Spatio-Temporal Characteristics of the Supply and Demand Coupling Coordination of Elderly Care Service Resources in China
Authors: Zhang Yijie , Zhang Mingli , Hu Haiju , He Xiaolong
Published: August 2022

The current situation and future development of the supply and demand coupling coordination of elderly care service resources reflect the level of elderly care service resource allocation. Whether factors affecting its development can be found is the key to promote the accurate allocation of elderly care service. Based on the coupling coordination model, the supply and demand of elderly care service resources, the development circumstance and the spatio-temporal evolution of supply and demand coupling coordination are analyzed in this paper by using the data of the elderly care service resources in 31 regions and autonomous regions in China from 2010 to 2019. The result shows that there are regional differences in the development of supply and demand coupling coordination of elderly care service resources. The degree of supply and demand coupling coordination of elderly care service resources in the western and northern regions is lower than that in the eastern and southern regions. Although the level in most areas of supply and demand coupling coordination of elderly care service resources will improve in the future, there is still a gap from good coordination. In order to strengthen the supply of elderly care service resources, and promote the upgrade of the supply and demand of elderly care service resources, the government should start from the demand of the elderly to increase investment in infrastructure construction, investment in elderly care services resources, talent training and other aspects.
Endometrial Cancer in Aspect of Forkhead Box Protein Contribution
Authors: Adamczyk-Gruszka Olga , Horecka-Lewitowicz Agata , Gruszka Jakub , Wawszczak-Kasza Monika , Strzelecka Agnieszka , Lewitowicz Piotr
Published: August 2022

(1) Background: The present study aimed to investigate the influence of forkhead box (FOX) on endometrial cancer (EC) progression. For a better understanding, the driving mechanisms are vital to identifying correlations between genes and their regulators. (2) Methods: The study enrolled one hundred and three white female patients with confirmed EC. For the analysis, we used next-generation sequencing with the Hot Spot Cancer Panel provided by Illumina Inc., San Diego, CA, USA, and an immunohistochemical analysis of FOXA1, FOXP1, and estrogen receptors. (3) Results: FOXA1 silencing led to a worse outcome based on the correlation with FOXA1 (test log-rank p = 0.04220 and HR 2.66, p = 0.033). Moreover, FOX proteins were closely correlated with TP53 and KRAS mutation. (4) Conclusions: Our study confirmed previous reports about FOX box protein in the regulation of tumor growth. A remarkable observation about the unclear crosstalk with crucial genes, as TP53 and KRAS need deeper investigation.
Manufacturer’s Encroachment and Carbon Emission Reduction Decisions Considering Cap-and-Trade Regulation and Consumers’ Low-Carbon Preference
Authors: Ding Fan , Lu Zhangping , Jin Mengfan , Sun Licheng
Published: August 2022

Carbon emission reduction and achieving carbon neutrality has become an inevitable trend in the sustainable development era. We investigate the manufacturer’s encroachment and carbon emission reduction decisions considering government cap-and-trade regulations and consumers’ low-carbon preference. The equilibrium decisions for the four scenarios are analytically obtained and compared based using the Stackelberg game. A comparison with and without cap-and-trade regulation under two encroachment decisions regarding member’s profits and carbon emission reduction levels are conducted. It is shown that the encroachment decision is always advantageous for the manufacturer if the government decides not to implement cap-and-trade regulation, and the retailer always loses profit. Moreover, if the carbon quota is sufficient, cap-and-trade regulation benefits the manufacturer. Otherwise, the manufacturer’s encroachment decision depends on the appropriate initial unit amount of carbon emission and unit carbon price. The retailer’s profit may not always be hurt by the manufacturer’s encroachment with cap-and-trade regulation; unless the unit carbon price exceeds a certain threshold, a higher consumer’s low-carbon preference in the encroachment scenario reduces more carbon emissions than in the no-encroachment scenario for the manufacturer. Further, the rising platform commission rate causes the platform profit to increase first and then decrease; the platform profit will slightly decrease if both products become more substitutes.
Psychometric Properties of the Italian Version of the 25-Item Hikikomori Questionnaire for Adolescents
Authors: Amendola Simone , Presaghi Fabio , Teo Alan Robert , Cerutti Rita
Published: August 2022

Hikikomori is a form of social withdrawal that is commonly described as having an onset during adolescence, a life stage when other psychiatric problems can also emerge. This study aimed to adapt the 25-item Hikikomori Questionnaire (HQ-25) for the Italian adolescent population, examining its psychometric properties; associations between hikikomori and psychoticism, depression, anxiety, problematic internet use (PIU), psychotic-like experiences (PLEs), to confirm convergent validity of the HQ-25; and the interaction effect between symptoms of hikikomori and PIU in predicting PLEs. Two-hundred and twenty-one adolescents participated in the study. Measures included the HQ-25, the Psychoticism subscale of the Personality Inventory for the Diagnostic and Statistical Manual of Mental Disorders, the Depression and Anxiety subscales of the Brief Symptom Inventory, the Internet Disorder Scale, and the Brief Prodromal Questionnaire. Data showed a satisfactory fit for a three-factor model for the HQ-25 that is consistent with the original study on the HQ-25. Three factors (socialization, isolation, and emotional support) were associated with psychopathology measures. Six participants reported lifetime history of hikikomori. Symptoms of hikikomori and PIU did not interact in predicting PLEs. This is the first study to validate the HQ-25 in a population of adolescents. Findings provide initial evidence of the adequate psychometric properties of the Italian version of the HQ-25 for adolescents.
Evaluation of Oral Mucosal Lesions Using the IllumiScan® Fluorescence Visualisation Device: Distinguishing Squamous Cell Carcinoma
Authors: Taguchi Yuki , Toratani Shigeaki , Matsui Kensaku , Hayashi Seiya , Eboshida Natsuki , Hamada Atsuko , Ito Nanako , Obayashi Fumitaka , Kimura Naohiro , Yanamoto Souichi
Published: August 2022

We evaluated whether fluorescence intensity (FI) and its coefficient of variation (CV) can be used to diagnose squamous cell carcinoma (SCC) through IllumiScan®, an oral mucosa fluorescence visualisation (FV) device. Overall, 190 patients with oral mucosal lesions (OMLs; SCC, 59; non-SCC OMLs, 131) and 49 patients with normal oral mucosa (NOM) were enrolled between January 2019 and March 2021. The FI of the images was analysed using image analysis software. After establishing regions of interest for SCC, non-SCC, and NOM, the average FI, standard deviation (SD), and CV were compared. There was a significant difference in the average FI for all pairs of comparisons. The SD was not significantly different between the SCC and NOM groups (p = 0.07). The CV differed significantly for NOM (p < 0.001) and non-SCC groups (p < 0.001) relative to the SCC group but was not different between NOM and non-SCC groups (p = 0.15). Univariate analysis of SCC and non-SCC groups showed significant differences for all factors, except age. However, multivariate analysis showed a significant intergroup difference only in the CV (p = 0.038). Therefore, analysing the CV in FV images of OML may be useful for the diagnosis of oral cancer.
Development of the Anthropometric Grouping Index for the Eastern Caribbean Population Using the Eastern Caribbean Health Outcomes Research Network (ECHORN) Cohort Study Data
Authors: Almodóvar-Rivera Israel A. , Rosario-Rosado Rosa V. , Nazario Cruz M. , Hernández-Santiago Johan , Ramírez-Marrero Farah A. , Nunez Maxime , Maharaj Rohan , Adams Peter , Martinez-Brockman Josefa L. , Tessier-Sherman Baylah , Nunez-Smith Marcella
Published: August 2022

Improving public health initiative requires an accurate anthropometric index that is better suited to a specific community. In this study, the anthropometric grouping index is proposed as a more efficient and discriminatory alternative to the popular BMI for the Eastern Caribbean population. A completely distribution-free cluster analysis was performed to obtain the 11 categories, leading to AGI-11. Further, we studied these groups using novel non-parametric clustering summaries. Finally, two generalized linear mixed models were fitted to assess the association between elevated blood sugar, AGI-11 and BMI. Our results showed that AGI-11 tends to be more sensitive in predicting levels of elevated blood sugar compared to BMI. For instance, individuals identified as obese III according to BMI are (POR: 2.57; 95% CI: (1.68, 3.74)) more likely to have elevated blood sugar levels, while, according to AGI, individuals with similar characteristics are (POR: 3.73; 95% CI: (2.02, 6.86)) more likely to have elevated blood sugar levels. In conclusion, the findings of the current study suggest that AGI-11 could be used as a predictor of high blood sugar levels in this population group. Overall, higher values of anthropometric measures correlated with a higher likelihood of high blood sugar levels after adjusting by sex, age, and family history of diabetes.
Does COVID-19 Fear Induce Employee Innovation Performance Deficiency? Examining the Mediating Role of Psychological Stress and Moderating Role of Organizational Career Support
Authors: Hossin Md Altab , Chen Lie , Hosain Md Sajjad , Asante Isaac Owusu
Published: August 2022

With the immense, short/long-term, and multidirectional effects of the coronavirus disease (COVID-19) pandemic on work performance, industry activities, and the national/global economy, it has adversely affected employees’ psychological well-being due to its elevated stress and anxiety that have substantially affected employee innovation performance (deficiency) (EIP(D)). The goal of this empirical paper is to identify how COVID-19 induces EIPD by examining the mediating role of psychological stress (PS) on the relationship between fear of infection with COVID-19 (FIC) and EIPD based on affective events theory (AET) and the moderating effect of organizational career support (OCS) on the relationship between PS and EIPD. Based on 865 survey responses provided by mid-level managers from Chinese manufacturing firms and the covariance-based structural equation modeling (SEM) technique using AMOS 25, we identified that FIC has a positive relationship with EIPD while PS can fully mediate the link between FIC and EIPD and OCS weakens the positive relationship between PS and EIPD (that is, in the presence of OCS, EIPD decreases despite the presence of PS among the employees). The findings of our empirical study will theoretically and practically contribute to the pandemic-related existing literature by providing an in-depth understanding of these variables. Furthermore, policymakers can also benefit by boosting their EIP from the outcomes revealed and suggestions provided.