bluuebunny/crossref_metadata_2025 huggingface dataset:
Estirpò ancora delli suoi paesi le strighe - The one (and only) report on the persecution of witches in the Nemanjic state
Authors: Hekic Benjamin
Published: December 2019

In the Copioso risretto de gli anali di Rausa (1605), written by the Ragusan
chronicler Jakov Lukarevic (Giacomo Luccari), we find a report on the
persecution of witches in the Nemanjic State. According to Lukarevic, grand
zupan Stefan Nemanja and tsar Stefan Dusan persecuted witches in their
country, and moreover, tsar Dusan burned the books of magic called
?Grominjak? in Slavic language. This report can?t be confirmed by any other
historical source, contemporary or later, but we think that Lukarevic didn?t
invent the story. We reckon that Lucarevic based his report on the
persecution of witches on certain historical events. The persecution of
heretics during Nemanja?s reign could?ve been that on which Lukarevic based
his story of Nemanja?s persecution of witches. In the time of Stefan Dusan
the legislation sanctioned the practice of magic (though, the practitioners
are predominantly termed as males); perhaps the tsar has persecuted
individually some wizards or sorcerers that had broken the law. But this
certainly couldn?t have been a true witch hunt, like those that Lukarevic
could?ve witnessed in his time. Likewise, Grominjak in fact could?ve been
the same as gromovnik, an astrological and meteorological manual used in
mediaeval Serbia for divination by thunders and earthquakes; this handbook
could?ve seemed to Lukarevic as a real grimoire used for summoning demons.
And since numerous manuscripts of gromovniks have survived, they obviously
hadn?t been systematically destroyed by the authorities. Our conclusion is,
therefore, that Jakov Lukarevic knew of some real events that were
influenced by his own experience and knowledge which ultimately shaped his
story into one of an early modern witch hunt ?transported? into mediaeval
Serbian state.
Notes from the life of Janko Veselinovic by Dragutin Dj. Tufegdzic
Authors: Popovic Radomir
Published: December 2019

Dragutin Dj. Tufegdzic (1881-1960), a teacher, priest and writer, was Janko
Veselinovic's son-in-law. After graduation from Sabac Grammar School (in
1897) and Teacher Training School in Aleksinac (in 1900), he first found
employment as a teacher. In 1906 Tufegdzic married Persida, Janko
Veselinovic's daughter, and in 1908 he was ordained priest. He served in
Badovinci in Macva District, and beginning in 1936, at St Mark's Church in
Belgrade, where he was dean (1941-1954). During 1931 he visited the holy
places in Palestine and became a pilgrim (hajji). Tufegdzic was a prolific
writer, contributor to Orthodoxy, The Voice of the Church, The Wreath, The
Bosnian Fairy, The Wheel Dance, The New Spark (Pravoslavlje, Glas crkve,
Venac, Bosanska vila, Kolo, Nova iskra) and other journals, the author of a
brochure, two novellas and a short story collection. As the heir to
Veselinovic?s manuscript legacy, during his lifetime D. Tufegdzic took
meticulous care of his father-in-law?s heritage. In The Wreath during 1913
and 1914 he published four notes from Veselinovic?s life (?Janko and the
Operator?, ?Janko and the Animal Doctor?, ?Janko?s Lottery Ticket? and
?Janko Responds to the Sergeant?), and they resemble the notes we present
here: ?From Janko?s Childhood?, ?Janko?s Last Christmas?, ?Janko?s
Gallantry? and ?Janko?s Last Living Moments?). The manuscripts are preserved
in the Intermunicipal Historical Archives in Sabac within the Presents and
Purchases Collection. The notes were edited according to their date of
origin and their call numbers in the Sabac Archives: ?From Janko?s
Childhood?, Belgrade, February 9, 1950, Collection (No. 18), ?Janko?s Last
Christmas?, Belgrade, February 9, 1950 (No. 19), ?Janko?s Gallantry?,
Belgrade, February 12, 1950 (No. 20), and ?Janko?s Last Living Moments?,
Belgrade, February 13, 1950 (No. 21). The notes were written on chequered
paper 21x33,5 cm in size. Although Tufegdzic wrote his memoirs of Janko
Veselinovic from a considerable time distance, his testimonies can be
considered authentic, because he got them directly from Janko?s daughter and
his wife Persida.
Increased Cardiovascular Response to a 6-Minute Walk Test in People With Type 2 Diabetes
Authors: Senefeld Jonathon W. , D’Astice Sarah E. , Harmer Alison R. , Hunter Sandra K.
Published: December 2019

Background and objective

Exercise is a cornerstone of management for type 2 diabetes; however, little is known about the cardiovascular (CV) response to submaximal functional exercise in people with type 2 diabetes. The aim of this study was to compare performance and CV response during a 6-minute walk test (6MWT) between people with type 2 diabetes and matched control subjects.

Methods

CV response and distance walked during the 6MWT were assessed in 30 people with type 2 diabetes, matched for age, body composition, physical activity, and estimated aerobic capacity with 34 control subjects (type 2 diabetes group: 16 men, 59.8 ± 8.8 years of age, 33.3 ± 10.9% body fat, physical activity of 7,968 ± 3,236 steps·day−1, estimated aerobic capacity 31.9 ± 11.1 mLO2·kg−1·min−1; control group: 19 men, 59.3 ± 8.8 years of age, 32.7 ± 8.5% body fat, physical activity 8,228 ± 2,941 steps·day−1, estimated aerobic capacity 34.9 ± 15.4 mLO2·kg−1·min−1).

Results

People with type 2 diabetes walked a similar distance (590 ± 75 vs. 605 ± 69 m; P = 0.458) compared with control subjects during the 6MWT and had similar ratings of perceived exertion (RPE) after the 6MWT (4.19 ± 1.56 vs. 3.65 ± 1.54, P = 0.147). However, at the end of the 6MWT, people with type 2 diabetes had a higher heart rate (108 ± 23 vs. 95 ± 18 beats·min−1; P = 0.048), systolic blood pressure (169 ± 26 vs. 147 ± 22 mmHg, P = 0.003), and rate-pressure product (18,762 ± 5,936 vs. 14,252 ± 4,330, P = 0.009) than control subjects.

Conclusion

Although people with type 2 diabetes had similar performance and RPE during the 6MWT compared with control subjects, the CV response was greater for people with type 2 diabetes, indicating greater cardiac effort for similar perceived effort and performance of 6MWT. These data suggest that observation and prescription of exercise intensity should include both perceived effort and CV response.
Research on pointing correction algorithm of laser ranging telescope oriented to space debris
Authors: Ma Tianming , Zhao Chunmei , He Zhengbin
Published: December 2019

This study aims to analyze four different telescope pointing correction models to verify the highest accuracy of the laser ranging telescope corrected by the back propagation (BP) neural network model optimized by the proposed genetic algorithm and Levenberg–Marquardt. In this process, first, the observation data of 95 stars are used to solve the coefficients of the four models, and then the pointing accuracy of the telescope corrected by those four models is verified by the detection results of 22 stars. The results indicate that the pointing accuracy of the telescope corrected by the three traditional pointing correction models, the mount model, the spherical harmonic function model, and the basic parameter model, reaches approximately 15 in. in the azimuth and ∼10 in. in the pitch; however, the BP neural network model optimized by the genetic algorithm and Levenberg–Marquardt has a pointing accuracy of 3.42 in. in the azimuth and 2.44 in. in the pitch. Finally, different space debris is detected by the telescope corrected by this model. The results show that the pointing accuracy of the telescope corrected by this model probably increases to nine times in the azimuth and three times in the pitch. The results of this study prove that the BP neural network model optimized by the genetic algorithm and Levenberg–Marquardt greatly increases the pointing accuracy of the telescope and thus significantly improves the success rate of space debris detection.
Pros and Cons of Raw Vegan Diet
Authors: Raba Diana-Nicoleta , Iancu Tiberiu , Bordean Despina-Maria , Adamov Tabita , Popa Viorica-Mirela , Pîrvulescu Luminiţa Cornelia
Published: December 2019

Diet has a major influence on both, human health and their behavior. Raw veganism is a diet that brings together two concepts: the one of veganism and the one of raw foodism, a diet that excludes all ASF (Animal Source Foods), all food cooked at a temperature above 48 °C (118 °F), and any food that is changed from its ordinary condition, and/or processed. The aim of the study was to bring more information about raw vegan diet and the controversy raw vegan versus cooked food. Scientific data taken into account recommend the use of the raw vegan diet mostly for a short period.
A new formula for the coefficients of Gaussian polynomials
Authors: Andrica Dorin , Bagdasar Ovidiu
Published: December 2019

We deduce exact integral formulae for the coefficients of Gaussian, multinomial and Catalan polynomials. The method used by the authors in the papers [2, 3, 4] to prove some new results concerning cyclotomic and polygonal polynomials, as well as some of their extensions is applied.
On L
′ (2, 1)–Edge Coloring Number of Regular Grids
Authors: Deepthy D. , Kureethara Joseph Varghese
Published: December 2019

In this paper, we study multi-level distance edge labeling for infinite rectangular, hexagonal and triangular grids. We label the edges with non-negative integers. If the edges are adjacent, then their color difference is at least 2 and if they are separated by exactly a single edge, then their colors must be distinct. We find the edge coloring number of these grids to be 9, 7 and 16, respectively so that we could color the edges of a rectangular, hexagonal and triangular grid with at most 10, 8 and 17 colors, respectively using this coloring technique. Repeating the sequence pattern for different grids, we can color the edges of a grid of larger size.
Leray–Schauder Alternatives for Maps Satisfying Countable Compactness Conditions
Authors: O’Regan Donal
Published: December 2019

In this paper we present Leray–Schauder alternatives for a general class of Mönch type maps.
On an improved computational solution for the 3D HCIR PDE in finance
Authors: Soleymani Fazlollah , Akgül Ali , Akgül Esra Karatas
Published: December 2019

The aim of this work is to tackle the three–dimensional (3D) Heston– Cox–Ingersoll–Ross (HCIR) time–dependent partial differential equation (PDE) computationally by employing a non–uniform discretization and gathering the finite difference (FD) weighting coe cients into differentiation matrices. In fact, a non–uniform discretization of the 3D computational domain is employed to achieve the second–order of accuracy for all the spatial variables. It is contributed that under what conditions the proposed procedure is stable. This stability bound is novel in literature for solving this model. Several financial experiments are worked out along with computation of the hedging quantities Delta and Gamma.
Existence results for an impulsive neutral integro-differential equations in Banach spaces
Authors: Usha Venkatesh , Baleanu Dumitru , Arjunan Mani Mallika
Published: December 2019

In this manuscript we investigate the existence of mild solution for a abstract impulsive neutral integro-differential equation by using semi-group theory and Krasnoselskii-Schaefer fixed point theorem in different approach. At last, an example is also provided to illustrate the obtained results.
Evaluating the Relationship Between Financial Sustainability and Socio-Economic Development of Countries
Authors: Kremen Viktoriia , Shkolnyk Inna , Semenog Andrii , Kremen Olha
Published: December 2019

This paper examines the mainstream theories of “financial sustainability” and “financial development”. It is suggested understanding “financial development” as the complex dynamic characteristics of the financial sector, which is formed under the influence of financial and economic policy factors and the financial market functioning. The paper provides the methodology of relationship between financial sustainability and socio-economic development of countries evaluation. Based on the matrix method, it is proved that the differences in developed and developing countries occur due to the relationship between financial sustainability and financial development.
Use of modelling for the renovation of drainage channels – The case of the Bouteldja plain in northeastern Algeria
Authors: Sennaoui Foued , Benabdesselam Tamara , Saihia Abdallah
Published: December 2019

Agricultural drainage has become a priority in agriculture and the economic development of the state. Algeria has launched several agro-economic projects pertaining to natural resources and human potential for development in agricultural areas. Our aim is to model the morphological evolution of open drainage channels, under the influence of sedimentary transport processes. The application of the Hydrologic Engineering Center’s River Analysis System (HEC-RAS) software is to examine two-phase mathematical models. In our case it is the flow and the sedimentary charge along a trapezoidal earth channel of a wetland north east of Algeria. The results of these models were validated by actual data obtained during the observation period from 2017 to 2018, for various rainy events. The solid transport and sedimentation velocity equations of Engelund and Hansen and Van Rijn respectively used by this model, give Nash performance criteria equal to 0.95 and determination coefficient R2 equal to 0.91. On the other hand, the laying of a coarse gravel layer of median diameter of the grains d50% = 60 mm on the bottom of the channels reduces the rate of sedimentation by about 32% over an 11-year period. This satisfying objective study of the modelling allows to obtain an approach to the renovation and a plan for new design of drainage systems, that participates to the sustainable development in the agricultural field.
Effect of water scarcity on households’ livelihoods in Iwoye-Ketu Area of Ogun State, Nigeria
Authors: Aromolaran Adetayo K. , Ademiluyi Ibiyinka O. , Sotola Abiodun E. , Wole-Alo Felicia I. , Aromiwura Oluwadamilola A. , Ogunsuyi Olubukola E.
Published: December 2019

Water is an essential commodity which affects life and livelihoods in the universe. This study examined perceived effect of water scarcity on livelihoods in Iwoye-Ketu, Ogun State. Random sampling was used to select 80 rural households and water samples for the study. Data collected were analysed using descriptive, inferential and laboratory analyses. Findings showed that the mean age of respondents was 38 years with an average household size of four persons. The major sources of water were boreholes (97.5%) and rainwater (90.0%), the average trekking time to the water source was 24 minutes and the households requires an average of 162 litres of water per day. Water analysis’ result showed that the water has pH (6.87), total dissolved solids (0.175 mg∙dm−3), temperature (29.9°C) and turbidity (0.6 FTU). The major causes of water scarcity include insufficient rainfall (97.5%), increased sunlight intensity (97.5%), pollution of water sources (95.0%) and increased population (93.8%). About 60% of them perceived water scarcity to have a negative effect on their livelihoods. Correlation analysis shows that there is a significant relationship between usage of water (r = 0.370, p < 0.01) and perceived effect of water scarcity. It was concluded that water available for household use is not sufficient, although it is safe but contain some elements which are not of World Health Organization standard for good potable water. It is recommended that the community should build a hub for water collection and distribution close to the village centre and the government should provide water infrastructures to increase the supply of potable water.
Characterization of the climatic drought indices application to the Mellah catchment, North-East of Algeria
Authors: Bendjema Lina , Baba-Hamed Kamila , Bouanani Abderrazak
Published: December 2019

Drought is one of the important phenomena resulting from variability and climate change. It has negative effects on all economic, agricultural and social sectors. The objective of this study is to rapidly detect climate dryness situations on an annual scale at the Mellah catchment (Northeast Algeria) for periods ranging from 31 years through the calculation of: the standardized precipitation index (SPI), the standardized Streamflow index (SSFI), the standardized temperature index (STI). Calculations made it possible to locate periods of drought more precisely by their intensity, duration and frequency, and detect years of breaks using the tests of Pettitt, rang, Lee and Heghinian, Hubert and Buishand. The use of the statistical tests for the rainfall series analyzed show all breaks, the majority of which are in 1996/1997 and 2001/2002. For the temperatures the breaks are situated in 1980/1981.
Current status and perspectives on offshore wind farms development in the United Kingdom
Authors: Dawid Leszek
Published: December 2019

The purpose of the article is to present perspectives for the development of offshore wind farms in the leading, in this respect, country in the EU and in the world – Great Britain. Wind power plays a remarkable role in the process of ensuring energy security for Europe since in 2016 the produced wind energy met 10.4% of the European electricity demand while in 2017 it was already around 11.6%. The article analyses the capacity of wind farms, support systems offered by this country and the criteria related to the location of offshore wind farms. The research has been based on the analysis of legal acts, regulations, literature on the subject, information from websites. The article shows that in recent years, the production of energy at sea has been developing very rapidly, and the leading, in this matter, British offshore energy sector is characterised by strong governmental support.
Geospatial and socioeconomic traits encumbering tractorisation of farmland among crop farmers in Ogun State, Nigeria
Authors: Lawal-Adebowale Okanlade A.
Published: December 2019

The objective of this study was to ascertain the socioeconomic and geospatial traits responsible for little or no usage of tractors for land clearing and cultivation by rural farmers in Ogun State, Nigeria. Data were obtained on the study objectives with use of interview guide, in-depth discussion and field observation a randomly selected 247 arable crop farmers. The obtained data were subjected to frequency count and binominal analysis of variance. Results showed factors such as farmers’ inability to afford tractor acquisition and/or hire tractors services (prop = 1.00, p < 0.05) as the major economic traits encumbering tractor usage for land preparation. The social traits included inadequate available of tractors to serve the farmers (prop = 0.76, p < 0.05), and farmers’ apprehension of possible destruction of soil structure and/or farm land (prop = 0.64, p < 0.05) as a result of tractor usage for land preparation. The geospatial traits were stump/tree distribution (prop = 0.97, p < 0.05) and land fragmentation (prop = 0.92, p < 0.05). It was thus concluded that both socioeconomic and farm geospatial traits interactively encumbered farm tractorisation in the study area. It was recommended that farmers should be supported technically and financially by stakeholders in agro-development so as to enable them to afford tractor usage for land cultivation.
Palm grove groundwater assessment and hydrodynamic modelling Case study: Beni Abbes, South-West of Algeria
Authors: Merzougui Touhami , Bouanani Abderezak , Rezzoug Cherif , Mekkaoui Abedrehmene , Hamzaoui Fadoua A. , Merzougui Fatima Z.
Published: December 2019

This paper presents the groundwater modelling of Beni Abbes palm grove in Southwest Algeria. Beni Abbes oasis alluvial aquifer is part of the Saoura Valley aquifer system, including a loose slick contained in a Quaternary alluvial embankment that fills the Beni Abbes basin. To address local needs, industry and agriculture, groundwater has been intensively exploited in recent years. Groundwater of the Beni Abbes oasis in the Saoura Valley oasis chain, is composed of a complex system, whose layer of alluvial terraces ensures a vital role for a 40-hectare palm grove. Due to its architectural position in the local aquifer system, the alluvial aquifer is mainly fed by the Great Western Erg and sometimes by the Saoura River floods. Based on the hydrogeological, hydrochemical characterisation and hydrodynamic modelling of the alluvial aquifer system of the Beni Abbes oasis, the mathematical model of finite difference and finite difference at steady state leads to the estimation of the hydrodynamic parameters of the aquifer and the evaluation of the complete water balance. The main results of this study provide a better understanding of the geometry and functioning of this aquifer currently in a state of concern. Furthermore, it is necessary to undertake integrated water resource management in this oasis in order to ensure sustainable development.
Spatiotemporal evolution of land surface temperature of Lake Oubeira catchment, northeastern Algeria
Authors: Rezzag Bara Chouaib , Djidel Mohamed , Medjani Fethi , Labar Sofiane
Published: December 2019

The difficulties of access and detailed measurements of land surface temperature (LST) and water surface temperature (WST) especially in wetlands made the use of remote sensing data as one of the sources and techniques to estimate many climate elements including surface temperature and surface emissivity (ɛ). This study aims to estimate the surface temperature of the wetland of Lake Oubeira located in northeastern Algeria and their spatiotemporal evolution in both land and water. Landsat OLI-TIRS images in two dates (April and September 2016) obtained from the USGS have been used in this work, and forms the basis of a series of operations to obtain the final LST: development of the normalized difference vegetation index (NDVI), conversion of the digital number (DN) of the thermal infrared band (TIR) into spectral radiance as well as the calculation of the effective luminosity temperature of the sensor from the spectral radiation and surface emissivity (ɛ).

The results show that the LST varies in space and time (from 16 to 31°C in April and from 24 to 41°C in September). This implies that the absorption of the equilibrium temperature at land cover depends on the optical properties of the surface, which are essentially determined by its water content, colour and morphology. At the same time, the water surface is the lowest land cover temperature, which also has a spatial variation (from 19 to 25°C in April and from 26 to 34.5°C in September) induced by atmospheric temperature, wind direction and speed and the depth of the lake.
Business model - an ephemeral trend or a claim of the future? the orientation of enterprises within the agricultural machinery sector
Authors: Nogalski Bogdan , Niewiadomski Przemysław
Published: December 2019

The fundamental objective of this research paper is to determine whether contemporary management is recognized traditionally, in the light of a strategy and the entailing methods of operation, adapted to the target recipients, based on knowledge and studies, strongly embedded in the market reality or perhaps more as a paradigm, in which the focal point is the architecture of business processes, which comprises a description of their conceptualization, the determination of individual and necessary stages of operations and the modelling of these process, i.e., a business model. Opinion reconnaissance requires – in the first place – to develop a catalogue of features clearly identifying a business model and a strategy. The theoretical and design layers will utilize a method of reconstructing and interpreting the source literature supported by a discussion among purposively selected experts. This will be reflected by a set of key identifiers, which quantify a strategy and a business model subject to further assessment by the representatives of agricultural machinery companies. On the empirical level, it is important to determine, which of the suggested dimensions truly capture the sense of the concept in terms of practical operations of the enterprises invited to the study. It seems that the complexity of the problems and the so far limited scientific recognition justify treatment of the mentioned issues as the subject matter of the research.
An attempt to determine the determinants of an effective impact of corporate social responsibility on consumer behaviour. A pilot study report
Authors: Spodarczyk Edyta
Published: December 2019

It is assumed that the idea of corporate social responsibility implemented by an enterprise will be appreciated by consumers. Consumers will be more willing to choose offers and support initiatives of socially responsible companies. Social responsibility, as a distinguishing mark used in positioning an enterprise (brand), also aims to contribute to building the loyalty of consumers who will be characterised, among others, by lower price sensitivity, and in their purchasing decisions they will be guided by the company’s positive image.

The above assumptions are partly correct. According to numerous studies, consumers favour socially responsible companies. They declare positive attitudes towards such enterprises and their good practices. The problem is that consumer activity in supporting responsible companies is often limited to declarations. The fact that the costs of social responsibility, as manifested in a higher price, are mainly to be borne by consumers is not emphasised. It turns out that good practices accompanying the offer (brand) are not always an important selection criterion for the consumer.

The purpose of the article is to attempt to define determinants of an effective impact of corporate social responsibility on consumer behaviour. By an effective impact, the author understands that corporate social responsibility is an important criterion for the choice of an offer by the consumer. The article presents a review of selected studies on the impact of social responsibility on consumer behaviour. The empirical part describes a pilot study in which an attempt was made to identify the reasons for the lack of an effective impact of social responsibility on consumer behaviour. Respondents’ opinions on measures to increase the effectiveness of the impact of social responsibility on consumer behaviour were also obtained.
Socially responsible university from the perspective of a student as a stakeholder – a pilot study report
Authors: Spodarczyk Edyta , Szelągowska-Rudzka Katarzyna
Published: December 2019

The article presents results and conclusions of a pilot study. This study aimed to determine the importance of distinguishing (model) characteristics for students of SRU, shaping mutual relations with students in five dimensions distinguished by the authors (values, relations, graduate, education, efficient organization) and to indicate the importance of these dimensions by students. It was found that education is the most important dimension for students, and it should be included in the social responsibility strategy implemented by the university, because it leads to the formation of a graduate desired in the modern labour market in the KBE. The features of particular dimensions identified by the authors were considered important by the respondents. They constitute a certain model to which universities can be compared, and which can be a hint as to what to look for when designing activities addressed to students as internal stakeholders of socially responsible university.
New business models for Cultural and Creative Institutions
Authors: Nikiel Sławomir
Published: December 2019

Total integration of social media and internet into daily life of the young people is the most distinct demographic characteristics of the Generation Z (born between 1995 and 2015). For Cultural and Creative Industries and Institutions in order to engage with this audience efficiently, their business models have to consider social media and more participative approach. The paper addresses the challenges and opportunities that face cultural institutions by analysing and assessing the business models related to new internet solutions. The paper provides a fresh review of the business models in which the author examines the new business model concepts through CCII subject-matter lenses. Discussed case-studies show generally successful result in activating Generation Z audience participation in cultural activities. While trying to understand limitations of the cultural institutions position and motivation towards social media and generally mobile internet, the paper raises critical implications of the pervasive internet in the CCII area.
An examination of the relationship between flexible work arrangements, work-family conflict, organizational commitment, and job performance
Authors: Ongaki Jacob
Published: December 2019

Many employees are often faced with an inter-role conflict between work and that of a family in the U.S. However, business leaders and Human Resource Management (HRM) may not recognize the problem affecting white-collar employees. The purpose of this non-experimental quantitative study was to determine whether or not a relationship existed between employees’ use of flexible working arrangements as predictor variables (such as flexible work schedules and telecommuting) and work-family conflict and family-work conflict as covariate variables, and organizational outcomes (such as organizational commitment and job performance outcome variables). The self-reported survey data included 237 employees who have utilized flexible work arrangements in service organizations in the state of Texas. The inconclusive ANCOVA parametric data assumption resulted in further employ Kruskal-Wallis statistical analysis with less restrictive normality assumption The ANCOVA and Kruskal-Wallis analyses tests revealed a statistically significant result for employees’ use of flexible work options (a combination of flexible work schedules and telecommuting) to alleviate family-work conflict. The use of a single option (flexible work schedules or telecommuting) was statistically insignificant to employees. Despite the rigorous study, limitations are inevitable particularly for self-reported data and non-experimental study. The difficulty to determine the participants’ honesty unintentional misrepresentations reflected in the validity of the study (Hunter, 2012; Matsui et al., 2005). Nevertheless, the study provided insight information to organizational management not to overlook the use of flexible work arrangement practices to mitigate employees’ family-work conflict (Gözükara & Çolakoğlu, 2015) to achieve organizational outcomes. Future researchers should replicate this study to include flexible work arrangement users vs. non-flexible work arrangement employees in other states, regions, and industries.
Accumulation of assets in farms covered by the FADN farm accountancy system in Poland – the economic and eco-efficiency context
Authors: Grzelak Aleksander
Published: December 2019

The primary objective of the article is to identify the accumulation processes in farms in Poland based on the economic size as well as the context of eco-efficiency (from the perspective of Environmental Sustainable Value). In addition, the importance of subsidies in generating accumulation was specified and the context of eco-efficiency was taken into account. Analysis of the environmental context was carried out with the use of the assessment of subsidies for public goods and return to cost ratio (RTC) based on the concept of Sustainable Value (SV). Cross-analysis has shown that with the transition to groups of farms with an increasing economic size, the situation was more favourable from the perspective of the accumulation rate and its level per 1 ha. Subsidies play a significant role in shaping accumulation. It was observed that the higher rate of accumulation associated with the transition to groups of farms with greater economic strength is accompanied by an increase in eco-efficiency through the prism of the RTC indicator. Larger (but not the largest) farms are more efficient in using the transformation of environmental inputs into production output, which does not mean that they exert an absolutely lower environmental pressure.
Design and Simulation of a Solar Energy System for Desalination of Brackish Water
Authors: Ennasri Hind , Drighil Asmaa , Adhiri Rahma , Fahli Ahmed , Moussetad Mohamed
Published: December 2019

In light of a sort of crisis of water scarcity which begins to loom worldwide as well as the economic constraints for achieving sustainable development, it becomes essential to find appropriate solutions to face this challenge. Morocco, which has considerable brackish water resources and an important solar resource deposit, is required to use desalination techniques; however, the reliability of such techniques can no longer be applied just in terms of their value as renewable sources of energy. The solution presented in this publication, establishes a rather reliable way to produce drinking water. The technique of desalination by reverse osmosis is considered in this study to be a promising technique. The objective of our study is the implementation of a prototype for desalination of reverse osmosis, which is a low-cost small unit used to treat brackish water based on solar energy.
THE DIRECT AND REMOTE RESULTS OF URGENT ANTIHYPERTENSIVE THERAPY AT THE PRE-HOSPITAL STAGE
Authors: Ruksin V. V. , Grishin О. V.
Published: December 2019

A comparison of the efficacy and safety of the ACE inhibitor captopril and the centrally acting moxonidine has been carried out. The randomized trial included 45 patients randomly divided into two groups. 24 patients received captopril, 21 patients received moxonidine. All patients received furosemide. From the very beginning of the study, blood pressure an heart rate was monitored during the day. It was shown that the efficacy and safety of the compared drugs in the first 30 minutes did not differ significantly. However, the effect of captopril, even in combination with furosemide, lasted no more than 6–8 hours, and moxonidine with furosemide — 18–24 hours. Cases of excessive decrease in blood pressure in both groups were rarely observed. Thus, the compared drugs in the first 30 minutes after administration do not differ in effectiveness. At the same time, daily monitoring of blood pressure showed that the effect of captopril more briefly. Moxonidine acts longer and allows you to more effec­tively control blood pressure fluctuations during the day. High efficacy and good tolerability of both drugs allow recommending them to patients as a means of self-help in case of high blood pressure. The use of daily monitor­ing of blood pressure allows to make therapy personalized.
ANALYSIS OF STRUCTURE AND FUNCTIONING OF HOSPITAL BEDS OF EMERGENCY DEPARTMENT IN THE RUSSIAN FEDERATION
Authors: Bagnenko S. F. , Miroshnichenko A. G. , Alimov R. R. , Razumnyj N. V. , Turov I. A.
Published: December 2019

29 emergency departments (ED) with hospital beds were functioning in 2018 in the Russian Federation (RF). Within the period 2014–2018 the bed capacity has been increased from 415 to 737, which portion is increased from 0,036% to 0,071% (in 2018 the portion of daily bed was 27,3%, the portion of the bed of short stay department was 72,7%). The number of discharged patients has been increased from 94545 to 306757. Therewith the portion of patients referred from ED to specialized units has been decreased from 19,0% to 11,1%. The average annual bed occupancy rate is 276,6 and 274,1. The bed turnover has been increased from 262,6 to 447,2. The lethal index is decreased from 0,18% to 0,13%. Bed population ratio keeps at the low level (5.0 bed per 1 million people which is rated as 4,5% from recommended values). Additional introduction of hospital departments of emergency medicine in 56 federal subjects of the RF al­lows quicker to achieve the goals of the National Project «Health care».
PERSPECTIVES OF USE LASER DOPPLER FLOWMETRY FOR ACCURATE DETERMINATION ОF DEGREE OF A BURN AT PREHOSPITAL STAGE
Authors: Yurova Yu. V. , Zinoviev E. V. , Krylov K. M. , Soloshenko V. V.
Published: December 2019

Objective of study was definition of opportunities to use laser doppler flowmetry for accurate determination оf degree of a burn at prehospital stage. This is the result of an study of 25 patients with burn injury in emergency room. It was found communication between indicator of the perfusion and depth of burn wound. It was installed value of the perfusion with help laser doppler flowmetry (ПМ — 1,0 PU), which is diagnostics significant criterion of depth of burn. If indicator of the perfusion is lower 1.0 PU, that is-deep burn, If indicator of the perfusion is above 1.5 PU, that is — superficial burn, indicator of the perfusion is between 1.0 and 1.5 PU, that is — borderline burn. It was developed diagnostic algorithm of treatment.
MEDICAL EVACUATION AT LIQUIDATION OF CONSEQUENCES OF EMERGENCIES: ROUTING, CRITERIA OF QUALITY
Authors: Baranova N. N. , Goncharov S. F.
Published: December 2019

Based on an analysis of expert assessments by specialists of the All-Russian Center for Disaster Medicine «ZASCHITA» on routing and quality criteria for medical evacuation, proposals have been developed for the development of a medical evacuation system for patients and injured in emergency situations. The main approaches to solving the problems of medical evacuation in emergencies are presented.
THE STATISTICAL IMPORTANCE OF INFLUENCE OF VARIOUS OPTIONS OF INFUSIONAL THERAPY ON PARAMETERS OF A HOMEOSTASIS OF PATIENTS WITH HEAVY TRAUMATIC SHOCK
Authors: Stepanov S. S. , Girsh A. O. , Stukanov M. M. , Leonov G. V. , Malyuk A. I. , Chernenko S. V.
Published: December 2019

In work it is presented that application of infusional therapy for patients with heavy traumatic shock at a prehospital stage is not only pathogenetic expedient, but also authentically reasonable component of antishock treatment. It is revealed that the most effective option of volemichesky compensation at patients with heavy traumatic shock at pre-hospital and hospital stages of treatment is application sterofundin isotonic and 4% the modified gelatin.
FIRST EXPERIENCE OF APPLICATION OF A STREPTOTEST AT THE PRE-HOSPITAL STAGE AND IN THE EMERGENCY DEPARTMENT OF THE CHILDREN’S HOSPITAL
Authors: Shaytor V. M. , Safronova A. I. , Klitsenko O. A. , Shaytor D. I. , Belyaev A. I. , Bruchikov K. V.
Published: December 2019

The publication presents the results of a comparative study of the use of diagnostic streptotest in the provision of emergency medical care and in the hospital. The possibility of differentiation of diagnoses in diseases of the upper respiratory tract and the development of early tactical and therapeutic measures at the stage of emergency and emergency medical care and in the emergency Department.
O sítio Serrano
Authors: Cordeiro Jeanne , Buarque Angela , Táboas Alice
Published: December 2019

O artigo aborda o contato entre franceses e tupinambá, tendo como suporte a historiografia do século XVI, fontes primárias, e a cultura material obtida em pesquisas arqueológicas realizadas no sítio Serrano, Araruama, Região dos Lagos, Rio de Janeiro. Serão discutidas as estratégias de dominação/instalação de europeus, franceses em particular, bem como a resistência e inter-relação das sociedades nativas no período que se seguiu, a partir da segunda metade do século XVI.
Gastroesophageal reflux disease and heartburn among the general population of Saudi Arabia
Authors: Al-Zahrani Sumayah , Mohamed Malikah , Mohammed Arub , Al-Harbi Nawal , Al-Qatari Basma , Alatwi Sarah , Al-Halal Doaa , Al-Matar Zainab , Saeed Rawan , Asiri Abeer
Published: December 2019

Background: Gastroesophageal reflux disease (GERD) is one of the most common upper gastrointestinal disorders that develop when a retrograde flow of stomach contents occurs leading to GERD symptoms or complications. The present study aimed at evaluating the prevalence of GERD and heartburn as well as their main characteristics and risk factors among the Saudi population, Saudi Arabia.
Methodology: A cross-sectional study was carried out on a random sample of the general population of Kingdom of Saudi Arabia, during the period from 1 January to 16 June 2019, using a pre-designed questionnaire for data collection.
Results: The study included 1734 participants; the majorities (76.8%) of the participants were females. The study reported that 17.8% of the Saudi population had GERD. There was a significant correlation between GERD and gender, age, BMI group, marital status, region and family history of GERD (P>0.05) but, there was no relation with average family income. It was more prevalent among females by 73.1% and among the age group 31-40 years by 32 %. Further, 38.8% of cases were with average weight, and more than half were married (57.6%).
Conclusion: The study concluded that 17.8% of the Saudi population had GERD. There was a significant correlation between GERD and gender, age, obesity, marital status, region, and family history of GERD.
Fanconi anemia: a single center experience of a large cohort
Authors: Kesici Selman , Ünal Şule , Kuşkonmaz Barış , Aytaç Selin , Çetin Mualla , Gümrük Fatma
Published: December 2019

Fanconi anemia (FA) is an inherited disease, characterized by congenital malformations, short stature, progressive bone marrow failure and predisposition to leukemia and solid tumors. The aim of this study was to evaluate the clinical and prognostic features of FA patients followed in a single center. The charts of FA patients were reviewed 35 years retrospectively and a total of 175 patients were included in the study in which 51.4% of patients were male. The mean age at diagnosis was 6.3±4.1 years. The incidence of microcephaly was 92.6%, skin findings were 88.0%, eye abnormality was 74.3%, thumb and radius abnormality was 53.1%, urinary system abnormality was 30.9%, skeletal system abnormality other than thumb and radius was 18.9%, genital system abnormality was 11.4%, cardiovascular system abnormality was 11.4%, ear and hearing abnormalities were 9.7% and gastrointestinal system abnormality was 5.7%. Short stature was present in 75.4% of the patients. Of the 175 patients 167 (95.4%) developed bone marrow failure during follow-up and the mean age of bone marrow failure was 7.1 ±3.7 years (1 month-old-19.8 years). The first clinical symptom was thrombocytopenia in 83.4% of patients. Malignancy developed in a total of 23 (13.1 %) patients (20 leukemia, 3 solid tumors) during follow-up. Of 175 patients, 35 (20%) underwent hematopoietic stem cell transplantation. Fatality rate among patients who underwent hematopoietic stem cell transplantation was 31.4% (11/35) and fatality rate among other patients was 63.4% (83/131; p < 0.05). Of 94 patients who deceased, death was due to bleeding in 44.7%, infection in 34%, leukemia progression in 16.0% and graft versus host disease in 5.3%. In terms of the number of patients included, this study is one of the largest cohorts with a remarkable duration of follow-up time. Hematopoietic stem cell transplantation was found to have a good impact on sur vival of patients.
New Provisions on Receiving and Handling Information and Report About Crimes and Petition to Charge in the 2015 Criminal Procedure Code and Recommendations
Authors: Hanh Tran Thu
Published: December 2019

The article discusses new provisions of the 2015 Criminal Procedure Code on receiving and handling information and report about crimes and petition to charge in comparison with the 2003 Criminal Procedure Code, as well as highlights some shortcomings of the provisions and propose recommendations for improvement.
Computational Strategies and Challenges for Using Native Ion Mobility Mass Spectrometry in Biophysics and Structural Biology
Authors: Allison Timothy , Barran Perdita , Cianferani Sarah , Degiacomi Matteo , Gabelica Valerie , Grandori Rita , Marklund Erik , Menneteau Thomas , Migas Lukasz , Politis Argyris , Sharon Michal , Sobott Frank , Thalassinos Konstantinos , Benesch Justin
Published: December 2019

Native mass spectrometry (MS) allows the interrogation of structural aspects of macromolecules in the gas phase, under the premise of having initially maintained their solution-phase non-covalent interactions intact. In the more than 25 years since the first reports, the utility of native MS has become well established in the structural biology community. The experimental and technological advances during this time have been rapid, resulting in dramatic increases in sensitivity, mass range, resolution, and complexity of possible experiments. As experimental methods are improved, there have been accompanying developments in computational approaches for analysing and exploiting the profusion of MS data in a structural and biophysical context. Here, based on discussions within the EU COST Action BM1403 on Native MS and Related Methods for Structural Biology with broad participation from Europe and North America, we consider the computational strategies currently being employed by the community, aspects of best practice, and the challenges that remain to be addressed.
X-Ray Crystallography and Free Energy Calculations Reveal the Binding Mechanism of A2A Adenosine Receptor Antagonists
Authors: Jespers Willem , Verdon Grégory , Azuaje Jhonny , majellaro maria , Keränen Henrik , García-Mera Xerardo , Congreve Miles , Deflorian Francesca , Graaf Chris de , Zhukov Andrei , Dore Andy , Mason Jonathan S. , Åqvist Johan , Cooke Robert M. , Sotelo Eddy , Gutierrez de Teran Hugo
Published: December 2019

Nowadays, rigorous free energy calculations are routinely considered in pharmaceutical design strategies. One typical sce- nario is the lead-optimization based on well-defined protein-ligand binding modes, inferred by pharmacological data in com- putational models and ultimately revealed by structural data. In this work, we reveal the molecular determinants of antago- nist binding to the adenosine A2A adenosine receptor (AR), an emerging target in immuno-oncology, via a robust protocol that connects structural and pharmacological data through free energy perturbation (FEP) calculations. Eight A2AAR binding site mutations from biophysical mapping experiments were initially analyzed with FEP simulations of each side-chain mutation, performed on alternate binding modes previously proposed in the literature. The results strongly suggested that only one binding mode could explain this experimental data, which was used to subsequently design a series of 11 chromone deriva- tives. The experimental affinities of these new compounds were linked through a cycle of ligand-FEP calculations around selected ligand pairs, which allowed the identification of the optimal positioning of the different chemical substituents in the proposed binding model. Subsequent X-ray crystallography of the A2AAR with a low and high affinity chromone derivative confirmed the predicted binding orientation, and provided new insights in the role of the explored substituents in the chro- mone scaffold.