bluuebunny/crossref_metadata_2025 huggingface dataset:
Panduan Konseling dengan Teknik Coping Self-Talk untuk Mengatasi Body Dysmorphic Disorder Siswa Sekolah Menengah Kejuruan
Authors: Fikriyah Aidatul , Simon Irene Maya , Lasan Blasius Boli
Published: February 2022

Abstract: This research and development aim to create a counseling guideline with coping self-talk technique to resolve vocational high school students' body dysmorphic disorder. It used a research and development model from Borg and Gall. The results of the assessment carried out by experts and field assessment on the user candidate were analyzed using the inter-rater agreement model. The validity index of the experts and users demonstrates very high criteria. This counseling guideline has followed the requirements from the National Education Standard Institution and four acceptability aspects so that it is feasible to be used.
Abstrak: Penelitian dan pengembangan ini bertujuan untuk mengembangkan panduan konseling dengan teknik coping self-talk untuk mengatasi body dysmorphic disorder siswa sekolah menengah kejuruan (SMK). Penelitian ini menggunakan model research and development yang dikembangkan oleh Borg dan Gall. Uji ahli dan uji lapangan calon pengguna dianalisis menggunakan inter-rater agreement model. Indeks validitas uji ahli dan calon pengguna menunjukkan kriteria sangat tinggi. Produk panduan konseling sudah memenuhi kriteria Badan Standar Nasional Pendidikan (BSNP) dan memenuhi empat aspek akseptabilitas sehingga produk sudah layak dan dapat digunakan.
Meningkatkan Self Disclosure Siswa Menengah Kejuruan Menuju Era Society 5.0 dengan Art Psychotherapy
Authors: Anggraini Helda Yusfarina , Sari Nina Permata , Rachman Ali
Published: February 2022

Abstract: Self Disclosure is essential for every individual to freely express himself and improve his emotional, cognitive, physical, and spiritual well-being. Art Psychotherapy can be used to increase Self Disclosure. This study aimed to determine the effectiveness of Art Psychotherapy in increasing Vocational high school students' Self Disclosure. A quasi-experimental design is used in this quantitative study. A total of six students of the eleventh grade Music Skills Program at SMK Negeri 4 Banjarmasin became the research sample selected using the purposive sampling technique. Art Psychotherapy is a treatment that is used and given in four meetings. The measuring instrument uses a scale of self-disclosure that has been tested for validity and reliability. Data analysis technique using Mann Whitney U Test and Wilcoxon Test. The result shows differences in the level of Self Disclosure before and after being given treatment. Overall, the technique is Art Psychotherapy effective for increasing Self Disclosure in vocational high school students.
Abstrak: Self Disclosure penting untuk dimiliki oleh setiap individu agar dapat dengan bebas mengekspresikan diri dan meningkatkan kesejahteraan emosional, kognitif, fisik, serta spiritual dalam diri. Penggunaan teknik Art Psychotherapy dapat meningkatkan Self Disclosure. Tujuan dari penelitian ini adalah untuk mengetahui keefektifan Art Psychotherapy dalam meningkatkan Self Disclosure siswa SMK. Penelitian ini menggunakan metode kuantitatif dengan rancangan quasi experimental design. Enam siswa kelas XI Program Keahlian Seni Musik SMK Negeri 4 Banjarmasin menjadi sampel penelitian yang dipilih menggunakan teknik purposive sampling. Art Psychotherapy adalah treatment yang digunakan dan diberikan sebanyak empat kali pertemuan. Alat ukur menggunakan skala Self Disclosure yang telah teruji validitas dan reliabilitasnya. Teknik analisis data menggunakan Mann Whitney U Test dan Wilcoxon Test. Hasil penelitian yang didapatkan yakni terdapat perbedaan tingkat Self Disclosure sebelum dan sesudah diberikan treatment. Secara keseluruhan, teknik Art Psychotherapy efektif untuk meningkatkan Self Disclosure pada siswa sekolah menengah kejuruan.
Pengembangan Panduan Teknik Flooding dalam Konseling Behavioral untuk Mereduksi Fear of Missing Out Siswa Sekolah Menengah Atas
Authors: Wati Ovita Dewi Sandra , Hotifah Yuliati , Ramli M.
Published: February 2022

Abstract: Research and development in this study aim to produce a product of Flooding technique guidance in Behavior Counseling to reduce Fear of Missing Out of high school students who are theoretically and practically acceptable. The design of this study uses research and development steps: preliminary studies, product development, and product testing. The guide was tested using a Likert scale and concluded with the Aiken rater agreement analysis. The test results show that the Flooding technique guide has been theoretically and practically acceptable to reduce high school students' Fear of Missing Out.
Abstrak: Penelitian dan pengembangan pada penelitian ini bertujuan menghasilkan produk panduan teknik Flooding dalam konseling Behavioral untuk mereduksi Fear of Missing Out siswa SMA yang berterima secara teoritis maupun praktis. Rancangan penelitian ini menggunakan Langkah penelitian dan pengembangan: studi pendahuluan, pengembangan produk dan uji produk. panduan diuji menggunakan skala Likert dan disimpulkan dengan analisis kesepakatan rater Aiken. Hasil uji menunjukkan bahwa panduan teknik Flooding telah berterima secara teoritis maupun praktis untuk mereduksi Fear of Missing Out siswa SMA.
Pengembangan "Perasaan Kita" sebagai Upaya Internalisasi Empati pada Siswa SMP
Authors: Muharammah Nanda Widya , Setiyowati Arbin Janu , Flurentin Elia
Published: February 2022

Abstract: One of the factors that cause cases of aggression that occur among adolescents is the low level of individual empathy. This research and development aim to develop the "Perasaan Kita" media as a student tool in the internalization of empathy. "Perasaan Kita" is a media in interactive books by utilizing the QR code feature in its use. A guidebook for school counselors also accompanies this media to provide essential services in schools. The research method used is research and development using the Borg and Gall model, adapted according to the situation and field conditions. Test material experts, media experts, and potential users evaluate the acceptance of the developed media by looking at accuracy, usability, and convenience. The research instrument uses an expert and prospective user assessment format. The material and media expert test results were then analyzed using the analysis of the inter-rater agreement model, while the results of the prospective user test were analyzed using the numerical average. The test results show that the "Perasaan Kita" media gets a high score, so it can be interpreted that the "Perasaan Kita" media is an appropriate medium used by junior high school students to internalize empathy.
Abstrak: Salah satu faktor penyebab kasus-kasus agresi yang terjadi di kalangan remaja adalah tingkat empati individu yang rendah. Penelitian dan pengembangan ini bertujuan untuk mengembangkan media "Perasaan Kita" sebagai upaya internalisasi empati siswa. "Perasaan Kita" merupakan media yang berwujud buku interaktif dengan memanfaatkan fitur QR code dalam penggunaannya, yang memenuhi kriteria akseptabilitas. Media ini juga disertai buku panduan bagi guru BK untuk memudahkan pemberian layanan dasar di sekolah. Metode penelitian yang digunakan yaitu research and development dengan menggunakan model Borg dan Gall yang telah diadaptasi sesuai dengan situasi dan kondisi lapangan. Uji ahli materi, ahli media dan calon pengguna memperhatikan keberterimaan media yang dikembangkan dengan melihat aspek ketepatan, kegunaan dan kemudahan. Instrumen penelitian menggunakan format penilaian ahli dan calon pengguna. Hasil dari uji ahli materi dan media kemudian dianalisis menggunakan analisis dari model kesepakatan inter-rater agreement sedangkan hasil uji calon pengguna dianalisis menggunakan rerata. Hasil uji menunjukkan bahwa media "Perasaan Kita" memperoleh nilai yang tinggi sehingga dapat diartikan bahwa media "Perasaan Kita" merupakan media yang sesuai untuk digunakan oleh siswa SMP dalam internalisasi empati.
Pengembangan Panduan Layanan Konseling Kelompok Berbasis Petualangan Untuk Meningkatkan Resiliensi Siswa SMP
Authors: Nurdestama Handika Mulya , Flurentin Elia , Ramli M
Published: February 2022

Abstract: The research aims to develop an adventure-based group counseling service guide to improve student resilience. Adventure-based group counseling services are packaged in a guide that contains daily activities by reflecting on the actual situation and includes treatments to increase resilience. The researcher uses the Research and Development design developed by Borg and Gall with research steps: (1) data collection, (2) planning, (3) product development, (4) expert testing, (5) product design revision, (6) stage test potential users, (7) revise the product into a prototype. Researchers did not conduct field tests due to the Covid-19 pandemic. In the expert test, the product is tested by two experts in terms of material and media and then tested by potential users. The results of the expert and prospective user test assessments show that the guide in the form of a prototype has met the acceptance criteria, so it is feasible to use.
Abstrak: Penelitian bertujuan mengembangkan panduan layanan konseling kelompok berbasis petualangan untuk meningkatkan resiliensi siswa. Layanan konseling kelompok berbasis petualangan dikemas dalam suatu panduan yang memuat aktivitas keseharian dengan merefleksikan situasi sebenarnya, serta memuat treatment untuk meningkatkan resiliensi. Peneliti menggunakan desain Research and Development yang dikembangkan oleh Borg dan Gall dengan langkah penelitian: (1) pengumpulan data, (2) perencanaan, (3) pengembangan produk, (4) uji ahli, (5) revisi desain produk, (6) tahap uji calon pengguna, (7) revisi produk menjadi prototipe. Peneliti tidak melakukan uji lapangan karena adanya pandemi Covid-19. Pada uji ahli produk diuji oleh 2 ahli dari segi materi dan media dan selanjutnya diuji oleh calon pengguna. Hasil penilaian uji ahli dan calon pengguna menunjukkan bahwa panduan berupa prototipe telah memenuhi kriteria keberterimaan, sehingga layak untuk digunakan.
SCIENTIFIC DEVICES AND INSTRUMENTS AS A SPECIAL KIND OF ARTIFACTS
Authors:   Institute for Analytical Instrumentation of RAS,  Saint-Petersburg, Russia, Ptitsyna I. B.
Published: February 2022

The history of artifacts (human-made objects) is as great as the history of mankind. Among the wide variety of artifacts, tools occupied an important place from the very beginning and, somewhat later, instruments. The development of society has always been accompanied by the need to increase the capabilities of these artifacts and their complications. All artifacts of this kind are extrasomatic organs — addition to bodily and mental organs — they are tools created to increase the ability to solve certain problems. With the development of technology, their capabilities have become so great that the question has arisen whether they exceed the capabilities of the human brain. This question is especially relevant for these kinds of tools that are created to assist the brain — self-learning computer programs of artificial intelligence. To understand this, one needs to turn to the origins of science, back to the day when the foundations of methodology and general principles for obtaining a mental product were laid. This result has a peculiarity: it is often perceived anthropomorphically, transferring the properties of the experimenter to the result of his activity. This is especially true for complex devices and instruments. The article shows the nature of the relationship between a person and an instrument as his artificial extrasomatic organ.
METHODOLOGY FOR ASSESSING THE QUALITY OF GENOMIC ASSEMBLY BASED ON THE ANALYSIS OF THE FREQUENCY OF K-MERS IN A PARALLEL SEQUENCING SEQUENCER
Authors:   Institute for Analytical Instrumentation of RAS,  Saint-Petersburg, Russia, Borodinov A. G. , Manoilov V. V. , Zarutskiy I. V. , Petrov A. I. , Kurochkin V. E.
Published: February 2022

Counting the occurrence of different k-mers often causes problems of genome assembly. Analysis of the frequency distribution of k-mers makes it possible to find assembly errors in already formed contigs. Currently, in connection with the development of instrumentation for genetic analysis, there is an urgent need to develop methods for assessing the quality of genomic assembly. Such techniques will make it possible to assess the reliability of genetic analysis in existing and newly developed devices. In this work, based on the analysis of various software tools, programs were selected to assess the quality of genomic assembly in parallel sequencing sequencers. Using the selected programs, the data obtained on the domestic sequencer for parallel sequencing Nanofor SPS were processed. Based on the results of processing these data, the quality of the genomic assembly was assessed by the method of analysis of k-mers and recommendations were given for improving the hardware and software of the Nanofor SPS device.
A motivação social da haplologia variável no português de Porto Alegre
Authors: Battisti Elisa , Oushiro Livia
Published: February 2022

O artigo trata da motivação social da haplologia sintática variável (dentro de casa::den’de casa, voltando de carro::voltan’de carro) no português brasileiro falado em Porto Alegre, capital do estado do Rio Grande do Sul. A análise quantitativa de dados de fala (cf. LABOV, 1972, 1994, 2001, 2010), de caráter exploratório, verifica que o processo, aplicado a sílabas iniciadas por /t/ ou /d/ em posição final e inicial de palavras em sequência na frase, (a) ocorre numa proporção total de 27,2% na fala de jovens; (b) correlaciona-se às variáveis sociais Mobilidade entre zonas e Renda e à variável linguística Estrutura da segunda sílaba. Os resultados sugerem que os efeitos de mobilidade na haplologia variável no português de Porto Alegre devam-se à persona jovem urbana cosmopolita que o processo, como recurso de identificação e distinção (cf. ECKERT 2000, 2018), auxilia a compor.
Ensinar português em Timor-Leste: relatos e reflexões
Authors: Brito Regina Helena Pires de , Bueno Alexandre Marcelo
Published: February 2022

Este trabalho apresenta, na primeira parte, duas experiências de ensino da língua portuguesa em Timor-Leste. Separadas pelo tempo, cada relato mostra diferentes problemas e distintas situações a partir das necessidades sociais, culturais e históricas da língua portuguesa em Timor-Leste. Na segunda parte, apresenta-se uma reflexão conjunta a respeito da formação de professores em Timor-Leste e, principalmente, uma defesa da necessidade de se conhecer as particularidades locais a partir de pesquisas de campo e de relatos das vivências dos profissionais que trabalham em projetos de cooperação internacional para se planejar adequadamente o ensino formativo e incentivar uma política de educação linguística mais efetiva.
A perífrase verbal trabalhar + de + infinitivo na língua portuguesa: de finais do século XIII a meados do século XVII
Authors: Machado José Barbosa
Published: February 2022

Pretendemos com este estudo identificar as ocorrências da perífrase trabalhar + de + infinitivo em obras que vão do português antigo (finais do século XIII) até ao português clássico (meados do século XVII), constatando a sua permanência no tempo e analisando o seu comportamento sintático e o seu valor semântico. Desenvolveremos os seguintes itens no nosso estudo: a presença da perífrase verbal no corpus selecionado; os tempos e modos do verbo semiauxiliar; os verbos principais presentes no segundo termo da perífrase; os pronomes pessoais clíticos dependentes quer do verbo semiauxiliar, quer dos verbos principais; alguns casos particulares, como o reforço do verbo semiauxiliar com outro verbo ou expressão verbal, o uso da perífrase sem a preposição de e o testemunho da sua presença no castelhano do século XV.
Atitudes e crenças sobre o uso de tu e você na variedade de Rio Branco
Authors: Camacho Roberto Gomes , Da Silva Marinete Rodrigues
Published: February 2022

A questão da avaliação subjetiva de variantes se assenta teoricamente no levantamento de crenças e atitudes a respeito de algum fenômeno variável próprio de línguas ou variedades dialetais em termos de atribuição de valores de prestígio e de estigma. Nesse âmbito, um fenômeno particularmente variável na variedade acriana de Rio Branco é o uso das formas de referência ao interlocutor. Em razão disso, o principal objetivo deste artigo é o de aplicar testes de avaliação de atitudes e crenças aos falantes dessa comunidade de fala para avaliar se há valores sociais de estigma e prestígio relacionado aos pronomes tu e você. Os resultados mostram que (i), por um lado, os dados obtidos com base na dimensão do poder apontaram para a existência de um valor de prestígio atribuído ao pronome você, que se origina, de modo geral, dos julgadores de grau superior de escolaridade; (ii) por outro lado, os dados analisados com base na dimensão de solidariedade apontaram para uma aceitação maior de todos os grupos de avaliadores por tu.
O papel do conector aliás na articulação de argumentos e na construção de imagens identitárias
Authors: Cunha Gustavo Ximenes
Published: February 2022

Procedemos, neste trabalho, ao estudo dos usos do conector aliás no último debate eleitoral da campanha à Presidência da República do Brasil, ocorrida em 2018, investigando o modo como as onze ocorrências do conector constantes do debate auxiliam na articulação e hierarquização de argumentos, na defesa de pontos de vista e na construção de imagens identitárias pelos candidatos. A perspectiva teórica que seguimos é a da Semântica da Enunciação (ou Pragmática integrada). No debate, identificamos dois usos do conector, um em que introduz um argumento suplementar e outro em que introduz uma correção ou retificação. Em ambos os usos, o conector, indicando rupturas enunciativas entre os argumentos que conecta, desempenha um papel estratégico. Empregando-o, o locutor busca atribuir diferentes graus de importância aos argumentos, graduar a maior ou menor amplitude de seu público-alvo, bem como poupar-se de ataques, corrigindo-se.
Investigando a categorização radial: o que nos ensinam os verbos de separação do português brasileiro?
Authors: Pinheiro Diogo , Muniz Jéssica Cassemiro
Published: February 2022

A Linguística Cognitiva tem se caracterizado pela crítica ao ideal de definibilidade clássica das categorias linguísticas. Uma questão, no entanto, permanece pendente: é possível demonstrar empiricamente que as categorias definidas por itens linguísticos não apresentam estruturação clássica? Para ajudar a responder a essa pergunta, este estudo apresenta uma investigação da semântica de três verbos de separação do português brasileiro: “cortar”, “quebrar” e “rasgar”. Para isso, um experimento de produção induzida, no qual os participantes deveriam descrever oralmente eventos de separação representados em vídeos curtos, foi rodado com 49 falantes nativos do português brasileiro. Os resultados, ao mesmo tempo em que apontaram para a validade da crítica cognitivista ao ideal de definibilidade clássica, permitiram delinear a estrutura semântica dos verbos “cortar”, “quebrar” e “rasgar” em termos de categorias radiais.
Propriedades coesivas e semânticas da construção complexa [com isso]conector à luz da linguística funcional centrada no uso
Authors: Lopes Monclar Guimarães , Da Silva Simone Josefa
Published: February 2022

[com isso]conector é uma construção complexa que atua na articulação de orações, períodos e parágrafos. Apresenta uma dupla função coesiva, já que é um mecanismo de sequenciação e referenciação. De um lado, a preposição com estabelece uma relação temporal, lógico-semântica ou discursivo-argumentativa entre diferentes unidades discursivas; de outro, o pronome demonstrativo isso encapsula porções precedentes de texto. Além disso, [com isso]conector é polifuncional – uma vez que pode exercer a função de sequenciador ou conector – e polissêmico – já que pode assumir valores semânticos de tempo, consequência, conclusão e elaboração. Os dados apresentados são descritos qualitativamente à luz da Linguística Funcional Centrada no Uso (cf. CUNHA et al., 2013; OLIVEIRA e ROSÁRIO, 2016, entre outros), em diálogo com estudos da Linguística Sistêmico-Funcional (HALLIDAY, 2004), da Pragmática (SWEETSER, 1990) e da Linguística de Texto (cf. KOCH, 2003; FÁVERO, 2004).
Processamento do sinal acústico em experimento dicótico
Authors: Scliar Cabral Leonor
Published: February 2022

Discute-se o processamento do sinal acústico da fala em escuta dicótica de pares mínimos simultâneos, diferindo apenas no primeiro segmento oclusivo, em paroxítonas bissilábicas CV, para verificar o efeito da alfabetização. Metodologia: Participaram 29 crianças com idade média de 7,3 ou 7,4 anos, pertencentes a dois níveis socioeconômicos médio-alto (NSEM) e baixo (NSEB), sendo dez alfabetizadas, pertencentes ao NSEM, oito, ao NSEB e onze não alfabetizadas, somente ao NSEB: as dos grupo alfabetizadas, ao término do 1º ano do EF e as do não alfabetizadas, no início. Resultados: embora sem diferenças significativas no número de respostas corretas, intrusões e blendings entre os alfabetizados e não alfabetizados, as respostas se diferenciam quanto às estratégias das duas populações. A alfabetização influencia na maior consistência nas estratégias baseadas na duração, enquanto as dos não alfabetizados são aleatórias, ou difusas. Comprova-se o processamento dos traços fonéticos distintivos que compõem o feixe dos fonemas.
Collision au carrefour de l’histoire des idées (linguistiques): Typographie, prosodie, pragmatique linguistique et herméneutique
Authors: Swiggers Pierre
Published: February 2022

Au début des années 1840, Marcellin Jobard, un industriel belge d’origine française, proposa une série de symboles typographiques nouveaux, qui devaient servir comme signes de sentiments (tels que l’ironie, l’irritation, la satisfaction) et comme signes des modulations prosodiques. Ses propositions, qui préfigurent les innovations modernes rendues possibles par les polices de logiciels spécifiques, visaient à rapprocher le texte écrit/imprimé de la production orale. Les idées de Jobard, qui n’ont pas eu de succès immédiat, répondaient à un projet de transparence herméneutique, à un programme sémiotique de continuité entre l’oral et l’écrit, et à un souci d’économie, qui apparaît dans l’exploitation d’une série réduite de formes graphiques tournées en différentes positions. Du point de vue de la pragmatique linguistique il est particulièrement intéressant de constater que Jobard proposait aussi des marquages typographiques spécifiques pour distinguer les différentes personnes (il)locutoires.
Os adágios da língua portuguesa na obra de Bento Pereira (1605-1681)
Authors: Henríquez Salido Maria do Carmo
Published: February 2022

Neste trabalho estudam-se enunciados breves, concisos e com força expressiva de caráter moral, transmitidos oralmente de geração em geração, resumidos na maioria dos exemplos em estruturas simples, bimembres ou trimembres, uma oração ou várias orações, ou fórmulas sintéticas como uma locução ou grupos muito heterogéneos de palavras, recolhidos por Bento Pereira como Adagios da Lingoa Portuguesa (1655). Elaboram-se umas notas sobre a origem da lexicografia em Portugal, a lexicografia bilingue (latim e português) e a relevância dos Tesouros. Incorporam-se comentários sobre a biografia e a obra do autor. Apresenta-se apenas uma ordenacão por palavras-nucleares que combina a ordem alfabética do nosso dicionarista e uma possível ordenação por domínios a partir das unidades lexicais documentadas na formulação de cada adágio, embora seja habitual que em muitos exemplos se entrecruzem vários domínios. Finaliza com as conclusões.
Apresentação
Authors: Cavaliere Ricardo
Published: February 2022

Apresentação à Confluência 62
Somatyczna embriogeneza: od odkrycia przez badania do praktycznego wykorzystania.
Authors: Mikuła Anna , Tomiczak Karolina , Grzyb Małgorzata , Tomaszewicz Wojciech
Published: February 2022

Komórki roślinne mają niezwykłą zdolność adaptacji do zmian środowiskowych. Jej przejawem jest tworzenie zarodków wprost z komórek ciała rośliny z pominięciem etapu zapłodnienia. Powstałe tą drogą strukturyrozwijają się w kompletne rośliny, a samproces, dla odróżnienia drogi powstawania i podkreślenia spójności z embriogenezą zygotyczną, jest określany mianem embriogenezy somatycznej (SE). Mimo, iż w2018 roku minęło 60 lat od opisania tego zjawiska po raz pierwszy, to mechanizm przeprogramowania komórki somatycznej w embriogeniczną nadal nie jest w pełni poznany. Jest to krytyczny etap wSE, który może być indukowany przez egzo- i endogenne czynniki oraz stresowe traktowanie. Działanie tych czynników na materiał roślinny wpływa na reorganizację struktury chromatyny, a tym samym na ekspresję genów, co w konsekwencji może uruchamiać program embriogenezy. W niniejszej pracy dokonano przeglądu aktualnej wiedzy na temat tego, jak określana jest tożsamość komórek totipotencjalnych oraz bodźców wymaganych do przeprogramowania rozwoju komórek somatycznych. Podsumowano wiedzę na temat kluczowych molekularnych regulatorów i związanej z nimi sieci powiązań, które kontrolują indukcję SE. Zdefiniowano równieżzagadnienia, które są ważne dla podniesienia zrozumienia mechanizmów leżących u podstaw totipotencji. Na zakończeniepokazano potencjał praktyczny drzemiący w tym procesie i podano przykłady jego wykorzystania.
Rola stresu oksydacyjnego i nitracyjnego oraz szlaku katabolitów tryptofanu w patogenezie depresji
Authors: Wigner Paulina , Śliwiński Tomasz
Published: February 2022

Depresja jest najczęstszą chorobą psychiczną, dotykającą około 350 mln ludzi na całym Świecie. Pomimo licznych badań, etiologia tej choroby nadal pozostaje niejasna. Dotychczasowe badania sugerują udział powiązanych ze sobą szlaków biochemicznych, tj.: stresu oksydacyjnego i nitracyjnego oraz nieprawidłowości szlaku katabolitów tryptofanu (szlak TRYCATs, ang. tryptophan catabolites pathway) w rozwoju zaburzeń depresyjnych. W związku z tym celem niniejszej pracy było wyjaśnienie roli stresu oksydacyjnego i nitracyjnego oraz zaburzeń przebiegu szlaku TRYCATs w molekularnym podłożu depresji. W niniejszej pracy podjęto próbę określenia wpływu polimorfizmów pojedynczego nukleotydu, zlokalizowanych w genach, kodujących enzymy zaangażowane w stres oksydacyjny i nitracyjny oraz szlak TRYCATs na częstość występowania depresji. Ponadto, wykorzystując model in vivo depresji dokonano oceny wpływu bodźców stresowych chronicznego łagodnego stresu na ekspresję na poziomie mRNA i ilość białka oraz stopień metylacji regionów promotorowych genów kodujących enzymy zaangażowane w badane szlaki. Uzyskane wyniki jednoznacznie potwierdziły udział badanych szlaków biochemicznych w patogenezie depresji na poziomie molekularnym.
Quality of Life among the Traffic Police Officers Working in Shyambazar Jurisdiction, Kolkata
Authors: Raja Alagesan Inba , Bisoi Sukamal
Published: February 2022

Background: As far as the working environment is concerned, traffic police officers are usually exposed to different health problems due to the nature of their work. This study aimed to assess the life quality of traffic police officers working in Shyambazar jurisdiction, Kolkata, India. Methods: A cross-sectional study was done by simple random sampling, on 115 traffic police officers, working in Shyambazar jurisdiction at Kolkata, India. The World Health Organization Quality of Life questionnaire (WHOQOL-BREF) was adopted. The four domains of the study were physical health, psychological health, social relationship and environmental health regarding the age and working experiences, and frequency, hours of work, and their mean scores were compared respectively. ANOVA and independent t-test were performed to interpret the results using SPSS software. Results: The mean age of the respondents was 37.5 ± 6.162. The mean of work experience was 11.2 ± 5.122 years. The overall life quality of the traffic police officers was good. The mean difference of work experiences was statistically significant (p<0.05) regarding the working environment. The mean difference of working hours was statistically significant (p<0.05) with respect to physical health. The mean difference of working frequency was statistically significant (p<0.05) concerning the social and environmental health domains. It was noted that environmental health was most affected followed by psychological and physical health. Conclusion: Making time for leisure and recreational activities along with regular counseling sessions for traffic police officers helps improve the quality of their life.
Increasing Hospital Noise Levels: a Worldwide Challenge
Authors: Abbasi Milad
Published: February 2022

The article's abstract is not available.
The Impact of Covid-19 Anxiety on the Quality of Life (QOL) of People Working in an Industry in 2021: a case study
Authors: Sobhani Seyvan , Sharif Hosseini Mohammad , Koroozhdeh Behnam , Tabanfar Sara
Published: February 2022

Background: This study was carried out aimed to investigate the effect of anxiety caused by Covid-19 on the quality of life of people working in the industrial sector. Methods: 212 people working in the industrial sector participated in a descriptive cross-sectional study using multi-stage random sampling. Data was collected using the Demographic Information Questionnaire, the Corona Disease Anxiety Scale (CDAS) and The World Health Organization Quality of Life–BREF (WHOQOL-BREF). SPSS statistical software version 24 was used for data analysis. The significance level of 0.05 is considered. Results: The mean age of participants was 33.27±6.6 years, 78.8% were male and 79.3% (168 people) were married. The mean scores of CDAS and WHOQOL-BREF were 11.60±8.2 and 64.66±10.8, respectively. The highest and lowest score of WHOQOL-BREF belonged to the dimensions of social relationships and mental health, respectively. There was a significant inverse correlation between CDAS and WHOQOL-BREF (P<0.001 and r = -0.656). Women had higher anxiety scores and lower quality of life than men. Individuals with a family member over 65 years of age or a member with a chronic illness had significantly higher mean anxiety scores and lower mean quality of life scores compared to other individuals. Conclusion: The results of this study show that the quality of life of employees in the industrial sector increases with reducing their anxiety. Therefore, it is recommended that factory managers take necessary measures to identify and eliminate the causes of anxiety to increase the quality of life and productivity of employees.
The Knowledge of Post Exposure Prophylaxis for Hepatitis B Virus and the Related Factors among Health Care Workers in Accra, Ghana
Authors: Senoo- Dogbey Vivian Efua
Published: February 2022

Background: Post Exposure Prophylaxis (PEP) of Hepatitis B virus (HBV) is important, especially in healthcare settings with low HBV vaccination uptake and high prevalence of HBV among the general public. It is important for Health Care Workers (HCWs) to have adequate knowledge of PEP for HBV for effective adherence following occupational exposure. This study assessed the level of knowledge of PEP for HBV among HCWs. Methods:  A cross-sectional study involving 174 HCWs from five facilities in the Greater Accra Region. Selection was by random sampling after stratification into six professional categories. A structured, pretested questionnaire was used to collect data. SPSS software was used to analyse data. Chi-square test was used to determine significance, ANOVA and logistic regression analysis were done. Results: Thirty three percent of the HCWs had knowledge scores of less than 50%, whereas only 27% had good knowledge of PEP for HBV. The average mean of knowledge score was 47.85 (CI=44.35-51.35). An analysis of variance identified a statistically significant difference between the scores obtained by the various cadres (P=0.01). A logistic regression analysis revealed that nurses and midwives had lower odds of having a good knowledge of PEP for HBV (aOR=0.4; 95% CI=0.1-0.9). Conclusion: Respondents demonstrated inadequate knowledge of PEP for HBV in this study. In poor settings where HBV disease burden is high and HBV vaccination coverage among HCWs is suboptimal, good knowledge of PEP for HBV is recommended for effective adherence to PEP protocols among HCWs, who are at risk of exposure to HBV.
Validity of Estimating the 3 kHz Audiometric Threshold by Averaging the Thresholds at 2 and 4 kHz in Cases of Noise-Induced Hearing Loss
Authors: Philippe Henri DeJonckere , Jean Lebacq
Published: February 2022

Background: Hearing thresholds at 3000 Hz are generally not measured in routine clinical audiometry. However, for purposes other than clinical diagnosis, the threshold at 3 kHz has many applications, in epidemiological studies in the field of occupational health and medicine, as well as in (medicolegal) quantification of physical impairment due to hearing loss, particularly noise-induced hearing loss (NIHL). The present study addressed the validity of estimating, in the case of NIHL, the 3 kHz-audiometric thresholds by averaging the thresholds at 2 and 4 kHz. Methods: All 200 investigated subjects (400 ears) had a well-documented noise exposure, moderate to severe NIHL, and underwent, as they were claiming for compensation, a detailed medicolegal audiological investigation, including beside pure tone audiometry, electrophysiological objective frequency-specific threshold definition using cortical evoked response audiometry (CERA) and auditory steady-state response (ASSR). Results: The study results showed a good correlation between the 2-4 kHz interpolation and the actual 3 kHz threshold; the error may be around 2 dB on average. However, in individual cases, the results demonstrated that the error due to interpolation exceeds 5 dB HL in about one-quarter of the cases. This error is predictable; the larger the 2- 4 KHz difference (which reflects the steepness of the left slope of the audiometric notch), the larger the error (on either side) made by interpolating. Conclusion: For epidemiological studies with large amounts of data, the interpolated threshold (average of 2 and 4 KHz) may be considered as a valid estimate of the true value of the 3 KHz threshold. More caution is required in individual cases: the error due to interpolation exceeds 5 dB HL in about one-quarter of the cases, but this error is predictable.
Implementation of Health, Safety and Environment Management System (HSE-MS) Requirements with Emphasis on Payment Management
Authors: Gholami Abdollah , Laal Fereydoon , Jamali Masoud
Published: February 2022

Background: In this study, the implementation of the requirements of health, safety and environment management system with emphasis on payment management in contracting companies has been compared. Methods: The current research is a cross-sectional study in which 200 persons were randomly chosen from a Krejcie and Morgan table as a sample (159 contractors of the gas company and 41 of the two contractors of the water and wastewater company). Two questions created by the researcher were included in the data gathering instrument. The first questionnaire included ten questions comparing HSE standards, while the second questionnaire had 28 questions comparing the two organizations' health, safety, and environmental indicators. Descriptive statistics and t-test were used to analyze the data. Results: The questionnaire's validity (qualitative content analysis) and reliability (Cronbach's alpha) were both validated as a consequence of the findings (0.879). Based on the findings, it was discovered that the Gas Organization's contracting companies implement the requirements of the health management system and safety better than the Water and Sewerage Organization of South Khorasan Province, and that the reason for this appropriate situation is the Gas Organization's emphasis on payment management (P<0.001). Conclusion: The results showed that the implementation of health, safety, and environmental management system requirements in the contracting companies of the Gas Organization is better than the Water and Sewerage Organization of South Khorasan Province. There are various aspects at play, and one of the most significant in the correct circumstances is the gas company's concentration on payment management.
Rapidly progressive dementia and severe awake bruxism resistance to treatment: An unresolved challenge to treatment
Authors: Bidaki Reza , Alizadeh Zahra , Sadeghi Milad , Zare Ali
Published: February 2022

Background: Bruxism is a chief complaint in some patients with dementia, but there is no clear guideline for its management.Here, we presented a case with awake bruxism.
Case presentation: This case report study described an 88-year-old woman with severe rapidly progressive dementia (RPD) and awake bruxism, which was improved with discontinuation of sertraline, quetiapine, gabapentin, and resumption of trazodone.
Conclusion: In this case study, despite taking drugs from different classifications for bruxism treatment, no improvement was seen. Bruxism is an important and challenging condition for physicians and caregivers in dementia patients. Although  bruxism needs serious treatment, there is no suitable and well-defined treatment for this disorder. Further studies are needed to suggest an efficient drug for the management of bruxism.
Vestibular schwannoma; dramatically response of facial Pain to carbamazepine and psychotic symptoms after tumor removal
Authors: Bidaki Reza , Asadi Mohadeseh , Cheraghali Hamed
Published: February 2022

Medical problems are common in psychiatric patients, especially in patients with schizophrenia, so more attention should be considered. Benign tumors such as Vestibular Schwannoma (VS) are also a rare condition that may occur in psychiatric patients. This study presented a 36-years-old married woman known case of schizophrenia and with cerebellopontine angle (CPA) following atypical facial pain. This study aims to draw the attention of physicians, psychiatrists, mental health personnel, and internal care to the physical and medical issues of chronic psychiatric patients. In addition, misdiagnosis in these patients can cause more problems, and drug-drug interactions can be important.
Ketamine as a novel treatment protocol for treatment-resistant major depressive disorder
Authors: Fallah Tafti Atena , Yasini Seyed Mojtaba , Saghafi Fatemeh , Bidaki Reza , Jafari Hossein , Vakili Mahmoud , Rameshi Yekta
Published: February 2022

Aims: Major depressive disorder (MDD) has devastating effects on patient's quality of life (QOL). It seems that the use of ketamine in the treatment of MDD is an easy and less invasive technique compared with invasive methods, such as electroconvulsive therapy (ECT). As there were few studies in this regard, especially in Yazd province, the current study aimed to evaluate the therapeutic effect of repeated injected ketamine on patients with MDD  and resistant to treatment.
Methods: This hospital-based open-label prospective study was conducted from September 2017 to May 2019 at Comprehensive Psychiatric Center, Taft,Yazd, Iran. In this pre-and post- trial, 18 patients with a diagnosis of MDD were recruited. The patients were diagnosed with MDD based on Diagnostic and Statistical Manual of Mental Disorders (5e) text revision Adapted from American Psychiatric Association (DSM 5). The patients aged between 18 to 70 years. Patients were eligible to participate in this study if they did not have history  of physical or mental comorbidity. After completing Hamilton Depression Rating Scale  (HDRS), the patients received 0.5 mg/kg ketamine infusion over 40 minutes with vital signs monitoring. After 2.5 hours of infusion, the HDRS was re-completed. The patients, who responded to treatment (≥50% reduction in HDRS score), received the treatment on days 3, 5, 7, 9, and 11 after the start of the study. Patients were re-evaluated after receiving the last dose of ketamine.
Results: After the first ketamine infusion, 13 of 18 (72%) patients responded to treatment. A significant decrease was seen between the mean depression score before (21.6 ± 8.5) and 2.5 hours after the first injection (9.7 ± 4.8) in responded patient (p<0.001). In addition, a significant decrease was seen in all of 13 patients who continued ketamine until the 11th day (6.3 ± 4.0) (p<0.001).
Conclusion: Findings suggested that ketamine injection was efficacious in reducing the severity of depression in patients with MDD. Due to the decrease in the average of HDRS score and the absence of significant side effects, it seems that repeated ketamine infusion therapy can be offered as a new therapy protocol for TRD.
The role of Ivermectin in COVID -19 |management, issues and challenges
Authors: Bidaki Reza , Afshang Habibollah , Zabihi Mohsen
Published: February 2022

The article's abstract is not available.
Evaluation of the Relationship of Concha Bullosa and Nasal Septal Deviation with Chronic Maxillary Sinusitis Based on Cone Beam Computed Tomography
Authors: Tafakhori Zahra , Pourabdolahi Mahboobeh , Sadeghi Mostafa , Khaleghi Mehran
Published: February 2022

Introduction: Due to the possible association between chronic sinusitis and anatomical variations of the area, the present study was performed to determine the prevalence of concha bullosa and nasal septal deviation and their association with chronic sinusitis to increase the success rate of nasal endoscopic surgery by eliminating the predisposing factors.
Methods and Materials: In this cross-sectional study, CBCT images of maxilla from 100 patients referred to the radiology department of Hamadan Dental School in the year 2016-2017 were examined. Pneumatization of middle concha (concha bullosa) on sides, nasal septum deviation, and mucosal thickening were recorded. Data were analyzed by Chi-square test based on gender and age (p value ≤ 0.05).
Results: The results showed that there was no significant difference between the mean age and sex with the presence of concha bullosa (p value > 0.05). 50% of the samples had nasal septum deviation and 42% had chronic sinusitis displaying no significant difference between men and women (p value > 0.05); Also, there was no significant difference between nasal deviation and chronic sinusitis (p value > 0.05), although chronic sinusitis was significantly higher in people with concha bullosa and while concha Bullosa was significantly higher in people with nasal septal deviation (p value < 0.05).
Conclusion: According to the results of the study, concha bullose can be considered as a predisposing factor for chronic sinusitis.
Titer and Prevalence of Fusobacterium Nucleatum in Histological Section of Human Oral Epithelial Cells in Patients with Chronic Periodontitis
Authors: Yahyaabadi Roya , Aminzadeh Gohari Atousa , Farhad Shirin Zahra , Ebrahimi Dastgerdi Mehrnoush
Published: February 2022

Introduction: Anaerobic bacteria in the oral microbial flora are involved in many infections of the oral cavity and surrounding structures. Fusobacterium nucleatum is believed to differ from other bacteria in its interaction with oral mucosal epithelial cells. The aim of this study was to determine the prevalence of Fusobacterium nucleotum in the epithelial cells of the oral mucosa of patients with periodontitis compared with healthy individuals.
Materials and Methods: In this case-control study, Realtime-PCR technique used to detect the Fusobacterium nucleatum in gingival samples of 15 patients with chronic periodontitis and 15 individuals with clinically healthy gingival specimens. The results analyzed by Fisher's exact and Independent t-tests with a significance level of less than 0.05.
Results: The Fisher's exact test showed that the F.nucleatum in patients with periodontitis was higher than the healthy population. Also Independent t-test showed that average titer of bacteria in patients with Periodontitis was significantly more than people without gingival inflammation (p value < 0.001).
Conclusion: There is a statistically significant relationship between periodontitis and the presence of F.nucleatum in epithelial cells of oral mucusa.
Compare the Prevalence of Temporomandibular Disorders in Class II Orthodontic Patients with and without Orthosurgery
Authors: Najafian Mohammad , Sadeghian Susan , Ehrami Eilnaz , Esnaashari Nasim
Published: February 2022

Introduction: Most orthodontists believe that orthodontic treatment does not cause TMD (Temporomandibular disorder), although some disagree with this. The aim of this study was to evaluate the prevalence of symptoms of temporomandibular joint disorders in class II skeletal patients in three groups with a history of orthodontic treatment, orthosurgery and no treatment
Materials and Methods: In this descriptive-analytical study, 99 adult skeletal patients of class II referred to the orthodontic department of Khorasgan in 2020 were selected. The prevalence of TMD was assessed in three subgroups: recipient of orthodontic treatment without orthosurgery, recipient of orthodontic treatment with orthosurgery treatment, and not receiving orthodontic treatment. Anamnestic and Dysfunction indices were assessed using Helkimo index and questionnaire. Data were analyzed by Kruskal-Wallis and Chi-square and Fisher's exact test (p value < 0.05).
Results: There was no significant difference in the severity and prevalence of TMD in adults with class II malocclusion among the three groups when comparing the anamnestic index and dysfunction index among patients with orthodontic treatment, orthosurgery and without treatment (p value < 0.05). In the examination of TMD in adults with class II malocclusion div1 and div2 among the three groups, there was no significant difference among patients with orthodontic treatment, orthosurgery and without treatment when compared with the anamnestic index and dysfunction index (p value < 0.05).
Conclusion: Severity and prevalence of TMD in adults with Class II malocclusion were no different in the three groups.
Quality of Life Related to Environment of Dental and Medical Student’s Life and Its Correlation with Stress
Authors: Tahani Bahareh , Jami Shiva
Published: February 2022

Introduction: The purpose of this study was to investigate the quality of life (QOL) score based on stress scale, the relationship between the two and their influencing factors in medical and dental students of Isfahan University of Medical Sciences.
Materials and methods: This cross sectional study was carried out on 235 dental students and 488 medical students between April-June 2020. In this study 24 items of physical quality, psychological quality, social quality, environmental quality and 2 general health items related to quality of life and 14 items related to stress level were assessed using the electronic questionnaire of WHOQOL-BREF. The collected data was fed into SPSS and analyzed by ANOVA, T-test, correlation coefficients and linear regression test (α = 0.05).
Results: The mean for total quality of life was 78.5 ± 14.1 (26-120) and 27.6 ± 7.2 (10-56), respectively. In both professions, the relationship between QOL and total stress showed a significant and inverse relationship (p value < 0.001, r = -0.78). In dental students, four domains and the total score were significantly higher and stress levels were significantly lower compared to medical students. In both professions, women had significantly higher levels of stress than men (p value = 0.03). Based on academic year, in medical students mean for total QOL scores (p value = 0.04), physical (p value < 0.001) and emotional quality (p value = 0.07) were significantly different and while the academic year increased, the QOL scores decreased.
Conclusion: There is a significant and inverse relationship between QOL and stress level. The level of stress in females is higher than in males and also in medical students than in dental students. The score of quality of life and academic year were inversely correlated.