bluuebunny/crossref_metadata_2025 huggingface dataset:
Gambaran Peresepan Antibiotik, Biaya, Efektifitas Terapi Pasien Demam Tifoid Rawat Inap RS Palang Biru Kutoarjo
Authors: Raharti Ima , Yuniarti Endang , Handayani Eka Wuri
Published: May 2022

Demam tifoid merupakan penyakit infeksi akut dan bersifat sistemik yang disebabkan oleh bakteri Salmonella typhy. Pada pengobatan demam tifoid diperlukan terapi antibiotik. Pengeluaran biaya antibiotik dapat mencapai 50% dari total anggaran obat namun belum bisa menjamin efektifitas dalam perawatan. Penelitian ini bertujuan untuk mengetahui gambaran pola peresepan antibiotik dan biaya perawatan pada pasien demam tifoid rawat inap di RS Palang Biru Kutoarjo. Penelitian ini dirancang dengan metode desain cross sectional. Pengambilan subyek penelitian menggunakan teknik purpose sampling dari populasi yang memenuhi kriteria inklusi periode Januari – Desember 2019. Data yang diperoleh dianalisis dengan metode statistik kemudia dibuat tabel dan disajikan secara deskriptif. Sampel dalam penelitian ini sebanyak174 pasien. Jenis antibiotik yang digunakan pada pasien demam tifoid rawat inap di RS Palang Biru Kutoarjo yaitu cefotaxim, ceftriaxon, ciprofloxacin, metronidazol, chloramfenicol, cefixim, amoxicillin, ampicillin dan cefadroxil. Pemakaian antibiotik paling banyak yaitu cefotaxim(51,9%) dan ceftriaxon (35,4%) dengan total biaya perawatan 2.737.851 dan 2.478.835
 
Kata kunci: Antibiotik, Demam Thypoid, Biaya, Efektivitas
Unsteady Stream-Tube Model for Pulse Performance of Bipropellant Thrusters
Authors: Oishi Yuki , Tauchi Soma , Inoue Chihiro
Published: May 2022

We propose a theoretical model for predicting the impulse bit of bipropellant thrusters under pulse-firing operations. The present theoretical model, which considers the nonuniformity of the mixture ratios created inside the thrust chamber, extends the stream-tube approach, which is limited to the prediction of the steady performance. In pulse-firing operation, the fuel or the oxidizer alone can be injected in isolation due to the mismatched injection timing before the rated injection, which leads to the deterioration of performance as compared with the steady operation. The present approach (the unsteady stream-tube model) successfully implements a time-dependent stream-tube structure inside the thrust chamber, allowing for the prediction of the impulse bit as a straightforward function of the injection conditions. Three different pulse-firing tests using distinct hypergolic propellants demonstrate the validity of this model, typically reproducing the notable trend of deterioration in the impulse bit in the short-pulsed mode. We also examine the time-averaged specific impulse and mass flow rate to improve the impulse bit during short-pulsed operations.
Oral pemphigus vulgaris: A case report and review of the literature
Authors: Rishi Sudhir , Chawla Pallavi , Dubey Deepa
Published: May 2022

The oral cavity presents with a variety of pathological lesions ranging from benign to malignant. Autoimmune mucocutaneous disorders of the oral cavity constitute an important group of lesions that pose diagnostic, therapeutic, and prognostic difficulties to the dental clinician. Many of the lesions may become potentially fatal if they are undiagnosed or misdiagnosed in their early stages. Pemphigus vulgaris is a potentially life-threatening autoimmune mucocutaneous disorder that causes blisters and erosions of the skin and the mucous membrane. It manifests clinically as vesicles, bullae, or desquamative gingivitis and histopathologically shows the presence of acantholysis. Eighty to ninety percent of patients with pemphigus vulgaris develop oral lesions and in 60% of cases, oral lesions are the first sign. Timely recognition and therapy of oral lesions are critical as they may prevent skin involvement. The incidence of pemphigus vulgaris occurs in a ratio of 2:1 (female: male). Adequate knowledge of diagnostic and therapeutic modalities helps the clinician in appropriate management. In this article, we report a case of oral pemphigus vulgaris in a 34-year-old male.
Imaging Microspectroscopic, Secondary Ion Mass Spectrometric and Electron Microscopic Studies on Discoloured and Partially Discoloured Smalt in Cross-sections of 16th Century Paintings
Authors: Boon Jaap J. , Keune Katrien , Van der Weerd Jaap , Geldof Muriel , Van Asperen de Boer J.R.J.
Published: May 2022

Paint cross-sections of five 16th century paintings with areas of discoloured smalt oil paint were investigated. Semi-quantitative SEM-EDX analysis revealed that potassium was relatively low in all discoloured smalts, while cobalt remained at an approximately steady level. Reflection
light microscopy demonstrated the presence of partially discoloured smalt particles with a remaining blue core. Imaging SIMS demonstrated that cobalt has a uniform distribution in the glass particles. Potassium however shows relatively high levels in the oil paint matrix around the discoloured
glass particles and an uneven distribution in smalt particles with a blue core. These blue cores always have a higher K level compared to the discoloured rim of the particle. The loss of potassium from smalt in oil paint is interpreted as a leaching process which lowers the basicity of the
glass below a critical level for colour maintenance. The colour change of the smalt is thus an indicator of a change in alkalinity inside the glass. The critical level appears to be near a K:Co of about 1:1 in 16th century potash glass on the basis of semi-quantitative SEM-EDX data. The migrated
K is thought to be accommodated on the many fatty acid groups of the mature oil network ionomer in the aged oil paint. Ca was observed in a number of blue remaining smalts which suggest a role in preservation of the blue glass or retardation of the leaching process. It is estimated that the
colour change is an early phenomenon possibly related to the early stages of oxidation and hydrolysis of the cross-linking oil paint. The differences in potassium levels in the remaining blue part of the smalt particles point to variability in the quality of the base potash glass in the 16th
century. Analysis of partially discoloured smalt from two panels of a triptych by Dirck Barendsz (1534–1592) demonstrated that he had access to two chemically different smalts.
Joint Attention Ability and the Neurocognitive functioning in children with Autism Spectrum Disorders
Authors: DAMIAN Ovidiu
Published: May 2022

Introduction: Autism spectrum disorders (ASD) have neurobiological origins but the exact nature of these brain dysfunctions has not been yet fully elucidated. Children with autism have difficulties in processing social and emotional stimuli, imitating body movements or interpreting relational gestures. These difficulties suggest as candidate factors related to autistic symptomatology, a specialised brain system involved in the mechanisms of social cognition, consisting in the medial temporal lobe (MTL) and the ventromedial prefrontal cortex (VMPFC). Objective: Our research examines whether young children with autism are impaired on neuropsychological tasks and also if the performance on such neurocognitive tasks can be correlated with joint attention ability (JAT). Methods: Three groups of children – with autism, with intellectual disability and with typical development, matched according to the mental age (calculated with the Fairview development scale, Giampiccolo & Boroskin, 1974) were administered neurocognitive and joint attention tests and procedures. Results: The results showed that only the MTL-VMPFC task performances were strongly correlated with the JAT behavior, while the dorsolateral prefrontal (DLPFC) ones were not. Conclusion: Our findings suggest that the VMPFC is involved in the development of JAT mechanisms. We found no correlation between the performance in tasks related to JAT behavior and the DLPFC factor. This means that autism is not associated, at least at young ages, with a unique pattern of poor executive functioning, so this dimension cannot be used as an indicator for the early diagnosis of autism.
COVID-19 Effect on Everyday Mobility of Different Demographic Groups of People with Blindness and Visual Impairment
Authors: SIKIRIĆ Dominik , MAŠIĆ FABAC Valentina
Published: May 2022

Introduction: The COVID-19 pandemic imposed some challenges on the mobility of people with blindness and visual impairment (BVI). Compliance with social distance epidemiological guidelines proved to be especially troublesome for those with BVI. Objective: The goal of this research was to determine the differences between specific demographic groups of people with BVI before and during the COVID-19 pandemic lockdown in everyday mobility, to identify the groups most affected. Methods: Forty-five people with BVI members of the Croatian Blind Union completed the questionnaire describing their pre-pandemic and lockdown independent everyday mobility activity frequencies on a 5-point Likert scale along with demographic questions in May 2020. Wilcoxon signed ranks test and paired samples t-test were used to test differences before and during the pandemic lockdown on average scale results for demographic groups. Results: A decline in independent everyday mobility between before and during the COVID-19 pandemic lockdown was shown for the total sample of people with BVI. When considering demographic groups both those with blindness and low vision, non-married and married, females, participants living in apartments, employed and unemployed participants, and participants living in a household with two members showed a statistically significant decline in independence during the pandemic. Males, retired participants, and participants older than 40, living alone in a house did not show a statistically significant decline. Conclusion: The decline in mobility functioning implies possible long-term effects of the pandemic lockdown on specific groups of people with BVI and additional support needed after the lockdown and the COVID-19 pandemic.
Legal Party Extraction from Legal Opinion Texts Using Recurrent Deep Neural Networks
Authors: Samarawickrama Chamodi , de Almeida Melonie , de Silva Nisansa , Ratnayaka Gathika , Perera Amal Shehan
Published: May 2022

Since the advent of deep learning based Natural Language Processing (NLP), diverse domains of human society have benefited form automation and the resultant increment in efficiency. Law and order are, undoubtedly, crucial for the proper functioning of society; for without law there would be chaos, failing to offer equality to everyone. The legal domain being such a vital field, the incorporation of NLP into its workings has drawn attention in many research studies. This study attempts to leverage NLP into the task of extracting legal parties from legal opinion text documents. This task is of high importance given the significance of existing legal cases on contemporary cases under the legal practice, \textit{case law}. This study proposes a novel deep learning methodology which can be effectively used to resolve the problem of identifying legal party members in legal documents. We present two models here, where the first is a BRNN model to detect whether an entity is a legal party or not, and a second, a modification of the same neural network, to classify the thus identified entities into petitioner and defendant classes. Furthermore, in this study, we introduce a novel data set which is annotated with legal party information by an expert in the legal domain. With the use of the said dataset, we have trained and evaluated our models where the experiments carried out support satisfactory performance of our solution. The deep learning model we hereby propose, provides a benchmark for the legal party identification task on this data set. Evaluations for the solution presented in the paper show that our system has 90.89\% precision and 91.69\% recall for legal party extraction from an unseen paragraph from a legal document. As for the classification of petitioners and defendants, we show that GRU-512 obtains the highest F1 score.
Geographic Entity Retrieval for Finding Places Suitable for Certain Purposes by Using Relevance Graphs on Places and Reviews
Authors: Maekawa Yui , Shoji Yoshiyuki , Durst Martin J.
Published: May 2022

This paper proposes a method of ranking geographic entities (places) where a purpose, given as a query, can be achieved. Most existing map search engines accept only the name of a place or the type of a place. Thus when searchers want to find a suitable place for ``guitar practice'', they have to input a place type such as ``music studio''. To create such a query, prior knowledge (\textit{i.e.}, that a music studio is suitable for playing guitar) is required. Our proposed method uses online review information on places to enable direct place retrieval from a given purpose query. Our method creates a bipartite graph consisting of places and the words that appear in the reviews of these places. The relevance between the given keyword query and a place is calculated by using the Random Walk with Restart algorithm. Additionally, we expand the graph with three hypotheses: 1) places that are suitable for the same purpose are similar to each other, and purposes that can be achieved in the same place are similar to each other, 2) the same purpose can be achieved in places with similar metadata, and 3) purposes which have semantically similar meaning can be achieved in the same places. Through an experiment using real review data taken from Google Maps, the usefulness of the proposed method was demonstrated. In particular, experimental result shows that the expansion by places' metadata is effective for finding more relevant places.
Doc2Vec-based Approach for Extracting Diverse Evaluation Expressions from Online Review Data
Authors: Kurihara Kosuke , Shoji Yoshiyuki , Fujita Sumio , Durst Martin J.
Published: May 2022

This paper proposes a method for extracting diverse expressions from online movie review texts for a given keyword query. When people watch a movie that makes them cry, they generally do not say ``I cried.'' Instead, they use such euphemistic language as ``I needed a handkerchief'' or ``My makeup was running.''To enable information retrieval based on audience reactions such as ``movies that make me cry'' using review texts, various paraphrased expressions must be collected for arbitrary queries. Our proposed method extracts such expressions from review datasets by applying two extensions to Doc2Vec: 1) it changes the granularity of the training sentences to mitigate a lack of context, and 2) it applies query expansion for similarity calculation in advance.We conducted a large-scale crowdsourcing experiment with 1.29 million actual sentences taken from Yahoo! Movies, Japan. The experimental result revealed that changing the training data granularity and adding the query expansion effectively collect more diverse expressions that have a meaning similar to the given query.
Erratum: On the extremal points of the Lambda-polytopes and classical simulation of quantum computation with magic states
Authors: Okay Cihan , Zurel Michael , Raussendorf Rovert
Published: May 2022

We will fix an error in the proof of Theorem 2 of the work On the extremal points of the $\Lambda $-polytopes and classical simulation of quantum computation with magic states by the current authors, published in Quantum Information and Computation Vol.21 No.13\&14, 1533-7146 (2021). The theorem as it is stated is still correct, however there is a gap in the proof that needs to be filled.
Activated Carbon Electrodes with Improved Sorption Capacity for Supercapacitive Swing Adsorption of Carbon Dioxide
Authors: Bilal Muhammad , Li Jiajie , Landskron Kai
Published: May 2022

Global warming due to anthropogenic CO2 emissions demands the rapid development of efficient carbon capture technologies. Supercapacitive swing adsorption (SSA) is a technology that relies on the reversible charge and discharge of supercapacitor electrodes to selectively adsorb and desorb CO2. A current limitation of SSA is the low sorption capacity. Here, we investigate a series of activated carbons derived from biomass, coke, coal, and carbide as electrode materials for SSA. The energetic and adsorptive performance metrics are quantitatively analyzed and their relationship with double layer capacitance, real capacitance, imaginary capacitance, and diffusion resistance is studied. The results show that there is a strong positive correlation between specific capacitance and CO2 adsorption capacity. The highest gravimetric sorption capacity was measured for garlic-root derived activated carbons valuing 273 mmol.kg-1 for 4 cm2 electrodes having a specific capacitance of 257 F.g-1. This is a ~4-fold increase compared to BPL 4x6 carbon having a specific capacitance of 86 F.g-1 and an adsorption capacity of 70 mmol.Kg-1. Volumetric specific capacitances and volumetric sorption capacities are also correlated. The highest volumetric sorption capacity was found for garlic powder-derived activated carbon valuing 65.3 mol.m3 at a volumetric specific capacitance of 62.3 F.cm3 which is a two-fold increase compared to BPL 4x6 carbon which has a volumetric specific capacitance of 41.2 F/cm3 and a volumetric sorption capacity of 27.1 mol.m3. In addition, higher specific capacitance tends to improve the overall adsorption rate and productivity.
Quantitative Predictions from Chemical Read-Across and Their Confidence Measures
Authors: Banerjee Arkaprava , Chatterjee Mainak , De Priyanka , Roy Kunal
Published: May 2022

In silico modeling new approach methodologies (NAMs) are viewed as a promising starting point for filling the existing gaps in safety and ecosafety data. Read-across is one of the most widely used alternative tools for hazard assessment, aimed at filling data gaps. However, there are no systematic studies or recommendations on the measures to identify the quality of read-across predictions for the data points without any experimental response data. Recently, we have reported a new similarity-based read-across algorithm for the prediction of toxicity (biological activity in general) of untested compounds from structural analogues (the tool available from https://sites.google.com/jadavpuruniversity.in/dtc-lab-software/home). Three similarity estimation techniques such as, Euclidean distance-based similarity, Gaussian kernel function similarity, and Laplacian kernel function similarity are used in this algorithm. As the confidence of predictions for untested compounds is important information, we have addressed this issue here by consideration of several similarity and error – based criteria. The role of these measures in discriminating high and low residual query compounds is studied in three different approaches: (a) comparison of means of a measure for high and low residual groups; (b) development of classification models for absolute residuals to identify the contributing measures; (c) application of the sum of ranking differences (SRD) approach to identify the measures closer to the reference rank defined by the absolute residuals. Finally, the frequency of occurrences of different measures in the three approaches is compared. The results from three data sets with 10 divisions of source and target compounds in each case indicate that weighted standard deviation of the predicted response values appear to be the most deterministic feature for the reliability of predictions followed by different similarity-based features. The derived reliability measures will provide a greater confidence to the quality of quantitative predictions from the chemical read-across tool for new query compounds.
Activity of metal-fluorine states upon delithiation of disordered rocksalt oxyfluorides.
Authors: Roy Indrani , Kumar Khagesh , Li Haifeng , Freeland John william , rodolakis Fanny , Cabana Jordi
Published: May 2022

The capacity of transition metal oxides as Li-ion battery cathodes is limited by instabilities that arise when high states of charge are achieved. Oxyfluorides with a disordered rock-salt structure have emerged as attractive alternatives, but the role of F in their electrochemical function, particularly when metals reach high formal oxidation states through cationic redox, remains to be ascertained. Using XAS measurements of Mn, O and F, we reveal the existence of Mn-F covalent interactions in Li2MnO2F and Li2Mn2/3Nb1/3O2F. New unoccupied states evolve from both Mn-F and Mn-O interactions when the phases are delithiated. The results challenge the assumption of F as largely a spectator ion, providing instead a nuanced picture of redox compensation in oxyfluorides. They suggest the existence of unique knobs of design of battery cathodes in these chemical spaces, by manipulating the covalent interactions between transition metals and two different anions.
A molecular-locked organic crystal imitating the connection mode of base pairs
Authors: Wung XiaoNan , Chen Humin , song xiaojing , wang di
Published: May 2022

At present, the biggest challenge for the development of organic electronic devices is the uncontrollable molecular structure of organic materials. For small molecule organic electronic materials, due to the lack of design, the arrangement between molecules is often uncontrollable and the formed crystals lack thermal stability. For polymer electronic materials, it is difficult to form ordered lattice, which greatly limits the improvement of its mobility. In this paper, we first proposed the strategy of ‘adjacent molecules can be locked to each other’ (TML) and designed and synthesized a TML molecule with bio-simulating the structure of DNA. Experiments show that TML molecules have good thermodynamic stability and electron beam radiation robustness. PL Spectrum and calculation verified that TML molecules had strong electron coupling, revealing its application potential in organic electronics. More importantly, TML molecules verify the feasibility of bottom-up construction of all-crystalline organic electronic materials.
Crystallographic–Morphological Paradoxes in Metal–Organic Frameworks
Authors: di Gregorio Maria Chiara , Singh Vivek , Shimon Linda J. W. , Lahav Michal , van der Boom Milko E.
Published: May 2022

The symmetry of a crystal’s morphology usually reflects the symmetry of the crystallographic packing. For single-crystals, the space and point groups allow only a limited number of mathematical descriptions of the morphology (forms), all of which are convex polyhedrons. In contrast, concave polyhedrons are a hallmark of twinning and polycrystallinity and are inconsistent with single crystallinity. Here we report unique metallo-organic crystals that exhibit, on the one hand, single crystallinity and, on the other hand, a concave, multidomain appearance and a rare space group (P622). Despite these contradictions, it is puzzling that the symmetry of these crystals is linked at different hierarchies, from the molecular to the microscopic levels. They exhibit a deceptive combination of the three characteristics that define a crystal at different length scales: the unit cell, the organization of these unit cells, and morphology. The structural properties of this system are intrinsic, as no other materials (additives) were used to shape the facets. The unusual concave morphology of the crystals can be a direct consequence of the open molecular packing often found in metal-organic frameworks. This fact has not been recognized before in these and other porous materials. Such crystals offer new opportunities for the formation of 3D objects where the physical properties can be designed and predicted based on the point group symmetry.
Uni-Mol: A Universal 3D Molecular Representation Learning Framework
Authors: Zhou Gengmo , Gao Zhifeng , Ding Qiankun , Zheng Hang , Xu Hongteng , Wei Zhewei , Zhang Linfeng , Ke Guolin
Published: May 2022

Molecular representation learning (MRL) has gained tremendous attention due to its critical role in learning from limited supervised data for applications like drug design. In most MRL methods, molecules are treated as 1D sequential tokens or 2D topology graphs, limiting their ability to incorporate 3D information for downstream tasks and, in particular, making it almost impossible for 3D geometry prediction or generation. Herein, we propose Uni-Mol, a universal MRL framework that significantly enlarges the representation ability and application scope of MRL schemes. Uni-Mol is composed of two models with the same SE(3)-equivariant transformer architecture: a molecular pretraining model trained by 209M molecular conformations; a pocket pretraining model trained by 3M candidate protein pocket data. The two models are used independently for separate tasks, and are combined when used in protein-ligand binding tasks. By properly incorporating 3D information, Uni-Mol outperforms SOTA in 14/15 molecular property prediction tasks. Moreover, Uni-Mol achieves superior performance in 3D spatial tasks, including protein-ligand binding pose prediction, molecular conformation generation, etc. Finally, we show that Uni-Mol can be successfully applied to the tasks with few-shot data like pocket druggability prediction. The model and data will be made publicly available at \url{https://github.com/dptech-corp/Uni-Mol}
Transforming the science of transformation toward sustainability: the case of ammonia and reactive nitrogen
Authors: Whalen J. Marc , Matlin Stephen A. , Holme Thomas A. , Stewart Jaclyn J. , Mahaffy Peter G.
Published: May 2022

Chemistry has played a central role over the past century in the large-scale anthropogenic transformation of matter into diverse materials that have improved the quality of life for many people on our planet. The lens of chemistry is fundamentally necessary to understand the resulting flux of chemical substances in Earth system processes, the unintended consequences of those transformations, impacts on food supply security, water and energy concerns, ways to mediate and adapt to climate change, loss of biodiversity, and how best to build and maintain resilient ecosystems. Reactive nitrogen compounds (Nr) such as ammonia from the industrial fixation of atmospheric nitrogen exemplify both the central importance of chemistry in providing food and meeting basic human needs for a global population of 7.9 billion people and the sustainability challenges arising from the intended and unintended consequences of large-scale human production and release of Nr. The chemistry profession can use the Planetary Boundaries framework as a systems thinking tool to understand and address challenges facing the entire Earth system resulting from the altered biogeochemical flows of nitrogen. This analysis has compelling priority due to the roles Nr currently plays in global food production and ammonia’s potential role as an energy carrier for large-scale human activities in a future low carbon economy. As this example illustrates, navigating the complex benefits and challenges large-scale human activity imposes on Earth system processes requires the convergence of chemistry research, industrial practice, and education. Since the chemical reactions and processes that transform matter are foundational to sustainability challenges, this perspective maps multiple levels at which chemistry can contribute toward the emergence of sustainability of the Earth system. We conclude with recommendations for steps the profession of chemistry can take to make education relevant and engaging and to connect chemistry research and practice to cross-disciplinary sustainability challenges.
The molecular structure and phase equilibria of molten fluoride salt with and without dissolved cesium: FLiNaK-CsF (5 mol%)
Authors: Sprouster David , Zheng Guiqiu , Lee Shao-Chun , Olds Daniel , Agca Can , McFarlane Joanna , Z Y , Khaykovich Boris
Published: May 2022

We demonstrate effects of Cs ions on the melting transition and molecular structure of molten FLiNaK (a eutectic mixture of LiF-NaF-KF). FLiNaK is a commonly studied multi-component model system, which represents the physical and chemical behavior of fluoride salts for nuclear energy applications. Dissolution of nuclear fuels leads to the formation of fission products directly in the molten salt. Cs is one of the most important fission products, due to its relative abundance, long half life, and potential environmental and health effects. Here, we determine the molecular structure and phase equilibria of dissolved Cs in FLiNaK by a combination of X-ray diffraction, X-ray total scattering, ab initio molecular dynamics calculations, and computational thermodynamics. Although Cs ions have a relatively large size, we did not find significant evidence that they disrupt the existing molecular structure of the liquid. We found good agreement between our simulated and measured structure factors, and calculated that the coordination number of Cs is close to 10. X-ray diffraction in combination with computational thermodynamics demonstrates that upon freezing Cs ions are captured into a CsLiF2 compound, with a lower melting temperature than the FLiNaK mixture and much higher than that predicted for CsLiF2 by computational thermodynamics. We also demonstrated a novel sample environment that we developed to X-ray measurements of molten fluoride or fuel salts.
El ingeniero industrial y la innovación tecnológica
Authors: Flit Isaías
Published: May 2022

La innovación tecnológica, implica cambios en la tecnológía de la producción industrial. Los empresarios industriales se enfrentan a cambios que obligan a modificar la tecnología empleada y a mejorar los procedimientos de elaboración de sus productos.
La ingeniería industrial y las filosofías de producción
Authors: Villegas Chamorro Ciro
Published: May 2022

No presenta resumen.
Simbiosis Universidad-Industria. Concepciones y experiencias cubanas en Ingeniería Industrial
Authors: Gallardo Capote Mariela , Benitez Almeida Estrella
Published: May 2022

Las autoras de este artículo pertenecen al Instituto Cubano de Investigaciones de los derivados de caña de azúcar; ellas nos muestran que el estudiante es el trabajador del futuro inmediato y tiene que estar en constante interación con las fábricas, empresas e industrias; conocer los problemas y trabajar sobre ellos, brindando las posibles soluciones.
La biología y el desarrollo: El ganado "Amazonas"
Authors: Cubas Vinatea Rafael
Published: May 2022

Presentamos a continuación un interesante artículo que se refiere al importantísimo campo de la biología en relación con el desarrollo económico.
Política económica y pequeña empresa industrial
Authors: Ochoa de la Cruz José Martín
Published: May 2022

En este artículo se destaca el interés que se debe otorgar a dos temas fundamentales: la pequeña empresa industrial y el desarrollo económico de nuestra nación.
Los principios de la filosofía Just-in-time de producción para elevar la competitividad
Authors: Villegas Chamorro Ciro A.
Published: May 2022

La potencia pretende demostrar que la filosofia de producción just in time de origen japonés, esta conformada por principios, objetivos, instrumentos y medidas de desempeño que permiten a las  empresas que la practican,  convertirse en empresas  de clase mundial.
El aprovechamiento del camarón gigante en el Perú
Authors: Kleeberg Hidalgo Fernando
Published: May 2022

El apreciado sabor y el alto valor económico son dos factores que han contribuido a la sobreexplotación del camarón de río, es por ello que la crianza intensiva  del camarón gigante se presenta como una alternativa de sustitución, por la facilidad y productividad en su cultivo.
La energía de la biomasa
Authors: Fernández Baca Marco
Published: May 2022

No presenta resumen.
Aditivos para combustible diesel como parte del mantenimiento preventivo
Authors: Salas A. José A.
Published: May 2022

No presenta resumen.
Proyecto empresarial peruano
Authors: Vega Monteferri Luis G.
Published: May 2022

No presenta resumen.
Estudio químico de la alga roja
Authors: Paz Castillo Berríos Juan Julio
Published: May 2022

No presenta resumen.
Extracción del aceite de jojoba
Authors: Díaz Bertha
Published: May 2022

No presenta resumen.
Layout Analysis of Goods Storage: Case Study Spare Part Warehouse Z Company
Authors: Wijaya Edo
Published: May 2022

This research is a case study to solve the problems that occur at PT. Z, which is engaged in palm oil processing. The case raised is the spare parts warehouse of PT. Z, where the problem that has occurred so far is the policy of random storage in the spare parts warehouse. This results in irregularities that complicate the process of receiving, storing, searching and releasing spare parts, which is indicated by the high total travel distance in the warehouse. Thus, the purpose of this study is to minimize the total travel distance in the spare parts warehouse by using a dedicated storage policy which is based on an analysis of the product storage layout (spare parts). Based on the results of data processing using a dedicated storage policy, the initial trip distance is 4257.25 meters and the proposed trip distance is 4002,5 meters. From these conditions, it can be concluded that using a dedicated storage policy can reduce the total travel distance in the spare parts warehouse by 254,75 meters or around 5,9%.
ПСИХОКОРЕКЦІЙНИЙ ВПЛИВ НА РОЗВИТОК ЖИТТЄСТІЙКОСТІ У ПІДЛІТКІВ В УМОВАХ ВОЄННОГО КОНФЛІКТУ
Authors: Басенко О. М. , Чернобровкін В. М.
Published: May 2022

У статті представлено результати дослідження впливу програми психологічної корекції та розвитку «Безпечний простір» на рівень життєстійкості підлітків, постраждалих внаслідок воєнного конфлікту на Сході України. Для діагностики рівня життєстійкості підлітків та оцінки ефективності програми використано такі методики: опитувальник «Сильні та слабкі сторони» SDQ (Strength and Difficulties Questionnaire), опитувальник психосоціального стресу у дітей CPDS (Child Psychosocial Distress Screener), скрінер оцінки психічного здоров’я КМА-УДХ (Mental Health Assesment Instrument), опитувальник з резильєнтності (життєстійкості). У дослідженні взяло участь 27 підлітків 14-17-ти років з м.Покровськ та м. Авдіївка (Донецька область). За результатами участі у програмі було виявлено зростання рівня життєстійкості та покращення показників психоемоційного стану учасників експериментальної групи. Аналіз отриманих даних засвідчив зменшення симптомів посттравматичного стресу, тривожності, депресії, схильності до зловживання алкоголем, а також покращення міжособистісних стосунків, зменшення проблем емоційного стану та поведінки, мінімізацію ризику інтерналізації завдяки зростанню таких факторів життєстійкості, як «відчуття щастя» та «підтримка батьків». Підтверджено, що зазначені фактори життєстійкості позитивно впливають на показники психічного здоров’я та утворюють специфічні захисні чинники, сприятливі для розвитку й зміцнення життєстійкості досліджуваної цільової групи. Сформульовано умови підвищення ефективності корекційно-розвиткових заходів для підлітків, постраждалих внаслідок подій воєнного конфлікту: попередня діагностика психологічного стану учасників з метою застосування диференційованого корекційного підходу та важливість врахування у процесі аналізу ефективності програми не тільки результатів загальних психометричних оцінювань, а й даних відповідних якісних методів (фокус-групи, індивідуальні інтерв’ювання тощо).
Yerleşik Yabancıların Destinasyon Marka İmajı Algılarını Belirlemeye Yönelik Bir Araştırma
Authors: SİPAHİ Güneş Açelya , TURAN MUTLU
Published: May 2022

Turizmin hizmet sektörü içerisinde önemli bir yeri vardır. Günümüzde insanların tatil anlayışları değişse de her koşulda tatil ihtiyaçlarının değişmediği görülmektedir. Yeni yerler görmek, farklı deneyimler yaşamak için insanlar bir yerden başka bir yere gitme ihtiyacı duymaktadır. S on yıllarda daha yaygın bir şekilde destinasyonda kısa süreli geceleme yerine o ülkenin vatandaşı olmasa da oraya kalıcı bir şekilde yerleşen veya yıllın belli bir bölümünü orada geçiren “yerleşik turist” ya da “yerleşik yabancı” olarak adlandırılan turist davranışları görülmektedir. İster uzun ister kısa süreli olsun insanların tatil için nereye gidecekleri ya da tekrar gidip gitmeyecekleri destinasyon olarak adlandırılan o yeri nasıl algıladıklarına bağlıdır. Bu nedenle destinasyon imaj algısının tespitine yönelik çalışmalara sıklıkla rastlanmaktadır. Literatürde; turistler, yerel halk, otel yöneticileri, yerel yönetimler ve turist rehberlerinin gibi kesimlerin destinasyon imaj algısını ölçmeye yönelik çalışmalar bulunmaktadır. Ancak çalışmanın amacı olan bir bölgede yaşayan yerleşik yabancıların o bölge ile ilgili destinasyon imaj algılarının tespit edilmesine yönelik bir çalışmaya rastlanmamıştır. Bu amaç doğrultusunda Amerika’dan iki kişi olmak üzere, Meksika, İrlanda ve Ukrayna’dan gelen beş yerleşik yabancı ile yarı yapılandırılmış derinlemesine mülakatlar yapılmıştır. Verilen cevaplar MAXQDA veri analiz programı ile analiz edilerek Kuşadası’na ait imaj algısının temel unsurlarının belirlenmesi amaçlanmıştır. Araştırma sonuçlarına göre Kuşadası’nın imajını oluşturan unsurlar; başta iklim, plajlar ve gün batımı manzarası olmak üzere doğal kaynaklar, güvenlik, ulaşım kolaylığı, sağlık hizmetleri ve sosyal ortam iken geliştirilebilecek konular, temizlik ve kış aylarında etkinliklerin artması şeklindedir. Ayrıca ortak bir destinasyon marka imajına yönelik belirsizlikler olduğu belirlenmiştir.
Relationship Between Language and Thought: Linguistic Determinism, Independence, or Interaction?
Authors: Li Jing
Published: May 2022

The relationship between language and thought has long been a topic of great interest in the field of linguistics, especially in psycholinguistics. Herder, Humboldt, Trendelenbury, Sapir, Whorf, Gui Shichun, Lian Shuneng, and Bao Huinan are some of the well-known scholars who have conducted research on the relationship between language and thought. With regard to the relationship between language and thought, there are three main viewpoints. The first group of scholars, represented by Sapir and Whorf, supports linguistic determinism. Some scholars believe that language and thought are mutually independent. However, others believe that language and thought are inseparable. Beginning from Sapir-Whorf hypothesis and their theory of linguistic determinism and linguistic relativity, this article agrees with the influence of language over thought but refutes the extreme viewpoint of linguistic determinism from several points, proving the independence and mutual influence of language and thought. This article finally concludes that the preferred relationship between language and thought should be that they are independent but interactive.
New Equipment Training Based on Virtual-Real Fusion Training Model
Authors: Zhu Min , Huang Huang , Guo Ming , Li Yan
Published: May 2022

In view of the phased development in college education, military training, and new equipment combat training, this paper proposes the virtual-real fusion training model of “five-in-one and step-by-step.” The five training modes, namely virtual panel training, immersive virtual training, physical (semi-physical) simulation training, training with equipped training equipment, and installation drill, are organically combined in the practical training of new equipment, which improves students’ innovation consciousness and serviceability.
Teaching Effect of Online Live Broadcasting with Screen Sharing and PowerPoint Recording and Broadcasting on Medical Students’ Learning of Obstetrics and Gynecology
Authors: Cai Yu , Jia Yuanyuan , Wang Siqi , Tian Chang , Feng Yu , Chen Rui , Wu Ge
Published: May 2022

Objective: During the prevention and control of the outbreak of the new coronavirus, an upsurge of online teaching was set off in various teaching institutions. There is a relatively new online teaching method that has stood out, namely the screen sharing method. The purpose of this study was to compare the effectiveness of live broadcasting and PowerPoint recorded lectures in terms of medical students’ mastery of knowledge. Methods: The study was carried out among medical students of class 1806 from the First Affiliated Hospital of Xi’an Medical University who were in their clinical years. The students were randomly divided into two groups, in which 15 students were enrolled in the live broadcast lecture group, while 13 were in the PowerPoint recorded lecture group. Each group underwent two weeks of teaching in obstetrics and gynecology. After the second week of the course, a knowledge post-test and satisfaction survey were carried out, and the same test paper was used again 14 days after the previous test. The knowledge post-test and satisfaction survey were carried out using the Dingding intelligent form. Results: With regard to the post-test knowledge, the scores of the students under the two teaching methods were high, indicating that the learning effects from the two methods are similar (p > 0.05). In terms of satisfaction, students showed more acceptance to screen sharing lectures (p < 0.01). Conclusion: In small-scale online teaching, live lecture with screen sharing is a better and more effective teaching method, and students are more likely to accept this teaching method.
A Summary of Lei Genping’s Experience in the Treatment of Chronic Nephritis
Authors: Zhang Yue , Lei Genping
Published: May 2022

Chronic glomerulonephritis involves multiple organs. It has a variety of clinical manifestations and is the major cause of progression to end-stage renal disease in patients with kidney disease. Professor Lei Genping believes that the treatment of this disease in Chinese medicine should be based on the deficiency and reality characteristics of the disease mechanism, distinguishing the priorities and identifying the strengths and weaknesses of the internal organs, as well as advocating the integration of Chinese and western medicine at the right time and in the right manner, in order to achieve fundamental results.
Are M1 and M2 macrophages Effectual Players in Pathological Conditions?
Authors: Abdollahi Elham , Saghafi Nafiseh , Hasanzade Malihe
Published: May 2022

Pathologic inflammatory conditions are frequently correlated with dynamic alterations through macrophage activation, with classically activated M1 cells associated with promoting and sustaining inflammation and M2 cells implicated in resolving or smoldering chronic inflammation. Inflammation is a common feature of various chronic diseases, and it has direct involvement in the emergence and progression of these conditions. Macrophages participate in an autoregulatory loop characterizing inflammatory process, as they produce a wide range of biologically active mediators that exert either deleterious or beneficial effects during inflammation. Therefore, balancing the ratio of M1/M2 macrophages can help to ameliorate the inflammatory landscape of pathological conditions. This review will explore the role of macrophage polarization in distant pathological inflammatory conditions, such as cancer, autoimmunity, renal inflammation, stroke, and atherosclerosis, while sharing macrophage-driven pathogenesis.
Clinical Value of Peripheral Blood Circulating Tumor Cells and Cell-Free DNA Combined Detection in Triple-Negative Breast Cancer
Authors: Sun Jirui , Ma Shuangqui , Chen Hong , Geng Huijuan , Zhang Jinku
Published: May 2022

Objective: To determine the clinical value of combined detection of circulating tumor cells (CTCs) and cell-free DNA (cfDNA) in peripheral blood of patients with triple-negative breast cancer. Method: 41 patients with breast cancer admitted to the First Central Hospital of Baoding from January 2020 to December 2021 were selected and recruited into the experimental group, 42 patients with benign breast cancer admitted during the same period were recruited into the conditional control group, and 41 healthy patients admitted during the same period were recruited into the blank control group. The positive rate of peripheral blood CTCs, the level of cfDNA, and the diagnostic efficacy of peripheral blood CTCs, cfDNA alone and the combination thereof for breast cancer were analyzed. Result: The positive rates of peripheral blood CTCs in the experimental group, the conditional control group, and the blank control group were 43.90%, 11.90%, and 9.74%, respectively, and there was significant difference among the groups. The levels of cfDNA in peripheral blood of the experimental group, the conditional control group, and the blank control group were 0.26 ± 0.08 bp, 0.17 ± 0.03 bp, and 0.15 ± 0.04 bp, respectively, which were statistically significant. The detection levels of 100 bp hTERT/ng·ml-1 and 241 bp hTERT/ng·ml-1 in the experimental group were significantly higher than those in the conditional control group and the blank control group. The accuracy of peripheral blood CTCs detection in the three groups was 66.21%, the accuracy of cfDA241 bp / 100 bp hTERT detection was 80.41%, and the accuracy of combined detection of peripheral blood CTCs and cfDNA was 94.03%. Conclusion: The clinical application of peripheral blood CTCs combined with cfDNA level detection can increase detection accuracy, provide data support for clinicians, and improve the clinical diagnostic effect of triple-negative breast cancer.
A Study on Corporate Public Diplomacy and National Image, Based on “16+1” Cooperation
Authors: Meng Jiao
Published: May 2022

Public diplomacy is an important aspect for the national development therefore, many enterprises are increasingly involved in the cooperation with different countries, in different fields, especially in the economy and trade market. In 2012, China established diplomatic cooperation and relationship with 16 different countries in the Central and Eastern Europe, subsequently leads to the establishment of the “16+1” cooperation platform. In the route of strengthening the cooperation between the two sides, more enterprises are participating in the economy and trade cooperation with different countries. A number of enterprises, are involved in the specific cooperation projects such as port construction, transportation, and financial cooperation. In the process of globalization, sharing, and integration of culture from different environments is something that due to happen, which may influence in the shaping of the country’s image.
Lin Zhao’en’s Ge-Wu Moral Cultivation Theory, and its Psychological Interpretation
Authors: Li Le
Published: May 2022

Lin Zhao’en is a folk religionist and ideologist in the late Ming Dynasty, who is influenced by Yangmingism. His practical theory on spiritual cultivation is widely influential, where he has thousands of followers up to now. He emphasis on the practice of Ge Wu, the concept of ‘The Great Learning,’ where the word ‘wu’ in ge-wu refers to ‘things in mind’ meaning the turn of wills. The ‘turn of wills’ refers to the psychological phenomenon of cognitive fusion, describing the relationship between an agent and their wills. The negative impact of the turn of wills, lies in the cognitive fusion between the people and their self-concept (conceptualized self), especially when dealing with external objects, which makes the perceptual function of the mind challenging to operate normally, further reduces the psychological flexibility of the mind. He also classifies ‘things in mind’ into three types, which are desires, biases, and the practice of deliberately doing good. This paper will discuss on the Lin Zhao’en practical theory and the concept of Ge Wu.
工程招投标中的违规行为及防范措施
Authors: 慧慧 谭
Published: May 2022

如今中国政府正处于行政审批改革阶段，政府职能发生了巨大改变，尤其是在建设工地领域，政府对招投标审批工作逐步予以重视。为了保证投标活动的规范化和合理化，政府逐渐开始应用信息技术，建立登记程序，实施二级登记政策，完善监督管理体制。其目的是简化审核流程，降低审核人员工作难度，保证其审核工作的范化科学。但是，受到多种因素影响，目前中国工程招投标市场仍较不规范，违规行为发生频率较高，不仅会影响招投标市场发展质量，还会阻碍建设工程行业发展水平。因此，工作人员需要对其引起重视，全面了解工程招投标过程中可能会出现各类违规行为并制定解决措施，从而提高招投标工作规范。基于此，论文以工程招投标工作为例，对其违规行为进行深入分析并制定预防措施。