bluuebunny/crossref_metadata_2025 huggingface dataset:
Conceptualizing Post-COVID-19 Malaysia’s Tourism Recovery: An Auto-Regressive Neural Network Analysis
Authors: Arokiasamy Anantha Raj A. , Smith Philip Michael Ross , Kijbumrung Thanapat
Published: September 2021

The pandemic caused by the SARS-CoV-2 virus (COVID-19) has significantly affected the tourism industry. Tourist destinations have adopted emergency measures and restrictions that have affected the mobility of individuals around the world. This study aims to analyze the effects of the COVID-19 pandemic on the tourism industry in Malaysia and its overall economic performance. This research used an extensive set of statistical tests, including a newly constructed Auto-Regressive Neural Network-ADF (ARNN-ADF) test, to determine if foreign visitor arrivals from 10 main source markets in Malaysia will revert to normal. Secondary data from various government published sources were used in this conceptual methodology technique for this study. Based on the research results and exploratory research of the literature, we listed in a synthesizing manner several measures to ensure the resilience of the tourism sector during the COVID-19 pandemic period. This research makes a significant contribution to the literature in terms of validating a new framework that emphasizes the effects of tourists that are largely transitory. In conclusion, this conceptual study will further help the authorities to take precautions and the best policy to be implemented in the future. Doi: 10.28991/esj-2021-SPER-10 Full Text: PDF
THEORY AND PRACTICE IN THE STUDY OF THE TIME PERSPECTIVE OF PERSONALITY: THE ABILITY TO ACT "IN THE MIND" OF YA.A. PONOMAREV
Authors:   School of Anthropology of the Future RANEPA, Pasternak Nina A.
Published: September 2021

The study was conducted as an empirical test of the model of mental development proposed by Ya.A. Ponomarev, who showed that the ability to act “in the mind” is one of the most important indicators of the overall development of the human psyche. Within the framework of these ideas, a comparative analysis of the features of time planning by first-year students of one of the Moscow universities of low (10 people) and high (10 people) levels of development of the ability to act “in the mind” through expert assessments of teachers of this university (40 people) protocols of students’ responses is carried out. As a result of the expert assessment, it was shown that with a low level of development of the ability to act “in the mind”, it is more difficult to systematically achieve the set life goals, plan your future based on a logical calculation. The study raises the question of the possible connection between “theory and practice” when taking into account the personal characteristics associated with a certain stage of the development of the ability to act “in the mind”, raises the question of the desirability of psychological support for a teenager when, due to the low level of development of this ability, planning for the future is difficult. It is postulated that if a practical psychologist provides such support in adolescence, practical psychology will be able to really influence the life path of a growing personality.
Evaluation of performance and early degradation of a 180.8 KWP rooftop on a grid-connected photovoltaic system in a Colombian tropical region environment
Authors: Audivet Cinthia , Romero Elena , García Jesús , Fonseca Ana , Pinzón Horacio , Bula Antonio , Sanjuan Marco
Published: September 2021

The use of renewable energy such as photovoltaic is growing. According to IRENA, these systems are one of the most dynamic generation technologies. The global photovoltaic market has grown rapidly between 2000 and 2016 at an annual average compound rate of 44%, from 0.8 GW to 291 GW. In Colombia, regions with high solar irradiation levels have been identified as emerging markets. The Government's plan is to increase the share of non-conventional energies in the energy matrix from 2% to 8% - 10%. However, the uncertainties associated with technology and sites specific degradation rates make it difficult to calculate accurate electricity generation efficiencies and predicting future performance and material degradation rates, and thus business models exhibit considerable deviations related to the real electricity generation rates. This work studies the performance and early degradation of a 180.8 kWp rooftop on grid connected photovoltaic system, installed in Barranquilla, Colombia. Two methods were used: i) estimation of solar conversion efficiency, and ii) visual inspection. The first method includes a cross analysis of climatic conditions, irradiance levels, and the generated energy downstream the inverters. The second method consists of periodical visual inspections of installed modules to check: discoloration, delamination, busbar corrosion, cracking of solar cell, glass breakage, anti-reflection coating, and solder bond.
Kewenangan Pemerintah Daerah Kabupaten Labuhanbatu Dalam Memberikan Perlindungan Terhadap Pekerja Anak
Authors: Siagian Duma Fitria Utami , N Nuribadah , Dameria Eny
Published: September 2021

Persoalan pekerja anak sebagai salah satu jenis tenaga kerja telah lama menjadi persoalan bagi masyarakat Indonesia banyak kekhawatiran yang muncul dengan keberadaan pekerja anak.Permasalahan pekerja anak di Indonesia ternyata tidak dapat disikapi dengan pilihan boleh atau tidak. Kenyataan menunjukkan kemiskinan adalah faktor utama yang mengakibatkan anak harus turut bekerja di usia yang masih sangat belia. Undang-Undang Ketenagakerjan dalam Pasal 74 (1) menyebutkan bahwa siapapun dilarang mempekerjakan dan melibatkan anak pada pekerjaan-pekerjaan terburuk baik itu pekerjaan yang membahayakan kesehatan, keselamatan atau moral anak.Penelitian ini bertujuan untuk untuk mengetahui dan menjelaskan kewenangan Pemerintah Daerah Labuhanbatu dalam memberikan perlindungan terhadap pekerja anak juga mendeskripsikan apa saja kendala dan upaya Pemerintah Daerah Kabupaten Labuhanbatu dalam memberikan perlindungan terhadap pekerja anak. Jenis Penelitian ini adalah Yuridis Empiris dengan pendekatan kasus yang dianalisis secara Kualitatif.Sumber data primer yang digunakan adalah wawancara dengan responden dan informan sedangkan sumber data sekunder adalah studi kepustakaan.Dalam Pasal 8 Peraturan Daerah Kabupaten Labuhanbatu telah menguraikan secara rinci dan tegas bahwa pemerintah daerah berkewajiban dan bertanggung jawab dalam memberikan perlindungan terhadap anak termasuk didalamnya mencegah, mengurangi resiko terhadap kekerasaan anak juga eksploitasi bagia anak.Berdasarkan hasil penelitian penulis faktor utama mengapa anak bekerja adalah himpitan ekonomi keluarga bahkan tidak sedikit anak harus berhenti sekolah untuk dapat membantu memenuhi kebutuhan hidup keluarga.
PENYELESAIAN SENGKETA TANAH WAKAF MASJID (STUDI KASUS DI GAMPONG ULEE TANOH KECAMATAN TANAH PASIR KABUPATEN ACEH UTARA
Authors: A Azriati , J Jamaluddin , H Hamdani
Published: September 2021

Studi ini bertujuan untuk mengetahui dan menganalisis faktor penyebab terjadinya sengketa tanah wakaf masjid di gampong Ulee Tanoh Kecamatan Tanah Pasir Kabupaten Aceh Utara, dan juga untuk mengetahui dan menganalisis proses penyelesaian sengketa tanah wakaf masjid di gampong Ulee Tanoh Kecamatan Tanah Pasir Kabupaten Aceh Utara. Gugatan yang dilakukan oleh si penggugat terhadap tanah wakaf masjid bahwa tanah yang sudah diwakafkan tidak memiliki akta wakaf sebagai alat bukti. Sehingga tampak bahwa tidak adanya akta wakaf menjadi sebuah alasan terjadinya gugatan terhadap tanah yang sudah diwakafkan. Kondisi tersebut membuat pihak penggugat semakin berani untuk melakukan gugatnnya, walaupun pada dasarnya bahwa mewakafkan satu benda cukup dilakukan dengan ikrar wakaf saja. Terkait tanah wakaf terdapat dalam Undang Undang Nomor 41 Tahun 2004 tentang wakaf, tetapi realita terjadi beberapa wakaf berjalan tidak sesuai dengan pengaturan tersebut. Penelitian ini menggunakan metode penelitian kualitatif dengan pendekatan empiris/yuridis sosiologis. Penelitian ini menghasilkan data deskriptif berupa kata-kata tertulis maupun lisan orang-orang atau perilaku yang diamati. Berdasarkan hasil penelitian diketahui bahwa sengketa tanah wakaf masjid ini adalah tidak memiliki akta wakaf sebagai alat bukti dan juga tidak adanya niat yang ikhlas dari ahli waris, yakni ahli waris dalam menerima kenyataan bahwa tanah ibunya sudah diwakafkan belum sepenuh hati secara ikhlas, serta dalam proses penyelesaiannya sengketa tanah wakaf masjid dengan pihak ahli waris terjadi kesepakatan perdamaian yaitu tanah wakaf masjid ini masih bisa digunakan seperti biasa oleh masyarakat dari ketiga kemesjidan. Namun pihak masjid, aparatur gampong beserta masyarakat harus membayar ganti rugi kepada ahli waris. Pembayaran dilakukan dengan cara dibayar secara cicil dalam seminggu sekali pembayaran dan dapat dilunasi pada akhir tahun 2019. Uang yang dibayar kepada anak si wakif berasal dari hasil wakaf masyarakat gampong dan luar gampong. Hak kepemilikan dari tanah tersebut sudah berpindah menjadi milik masyarakat gampong Ulee Tanoh, Mee Meurubo, Matang Ranub Laseh, serta kaum kaum muslimin dan muslimat.
Tinjauan Yuridis Perjanjian Kuasa Menjual Mutlak Dalam Transaksi Jual Beli Tanah.
Authors: Helmi Nurul , Afrizal Teuku Yudi , F Fatahillah
Published: September 2021

Studi ini bertujuan untuk mengetahui dan menjelaskan kedudukan hukum perjanjian kuasa jual mutlak oleh pembeli hak atas tanah dalam transaksi jual beli tanah, beserta untuk mengetahui dan menjelaskan akibat hukum yang timbul dari perjanjian kuasa mutlak dalam transaksi jual beli tanah dan untuk mengetahui dan menjelaskan perlindungan hukum kepada pihak pembeli tanah berdasarkan kuasa mutlak dalam peralihan hak milik atas tanah.
EKSISTENSI PERKAWINAN EKSOGAMI MASYARAKAT SUKU GAYO DI LINGKUNGAN PERKOTAAN DAN PERDESAAN (Studi Penelitian di Kecamatan Lut Tawar dan Kecamatan Linge Kabupaten Aceh Tengah)
Authors: Beru sembiring Nofrin Ariska , J Jamaluddin , F Faisal
Published: September 2021

Abstrak

The Gayo tribe community is prohibited from carrying out exogamous marriages for several reasons, one of which is that they consider one clan / split to be one offspring. The Gayo tribe community still maintains this custom and cannot be violated, if the Gayo people marry into one clan / split or one village with girls in the village then this is considered a disgrace and will have a direct impact on being ostracized by the community in that village. Communities who carry out exogamous marriages will be subject to customary sanctions in the form of farak (exile) which is decided by customary deliberations conducted by Sarak Opat (customary institution). But in reality, there are still Gayo people in urban and rural areas who carry out exogamous marriages.
This study aims to determine and explain the Exogamy Marriage Exogamy of the Gayo Tribe between urban and rural areas in Central Aceh Regency, to find out and explain the legal consequences of exogamous marriages in urban and rural areas for the Gayo tribe in Central Aceh District and efforts to resolve customary sanctions given to people who carry out exogamous marriages in Central Aceh District.
This study uses a qualitative method with an empirical juridical approach. Data obtained through library research (library research) and supported by field research (field research). Data analysis was carried out descriptively (descriptive analysis).
Based on the results of the research, it is known that exogamous marriage in urban communities has maintained the prohibition of marrying one clan / split until now, while in rural communities the prohibition of marrying among tribes is not really cared about because there has been a shift in customs in the countryside. So that the customs in the Gayo Tribe, not all people of Central Aceh District comply with the customary prohibition of exogamous marriage. The leniency of customs in several places, especially in Linge District, is because the majority of pentani communities from outside the region who carry out exogamous marriages due to ignorance of local customary rules.
It is recommended for the community to continue to maintain the customs in the Gayo Tribe. Gayo and Reje Adat Majlis so that they can provide guidance to all rural communities so that they understand and know the local customs rules because the Gayo Tribe customs are the norms (rules) for all people in Central Aceh Regency that must be obeyed.

Keywords: Exogamy Marriage of the Gayo Tribe, Traditional Gayo Tribe, Sanctions of Gayo Tribe Customary Law, and Differences in the Application of Gayo Customs.
PERLINDUNGAN HUKUM BAGI KONSUMEN TERHADAP PENGGUNA KOSMETIK YANG TIDAK TERDAFTAR BADAN PENGAWASAN OBAT DAN MAKANAN (BPOM) (Studi Penelitian Di Kota Idi Kabupaten Aceh Timur)
Authors: Humaira Ayu , Y Yulia , F Fatahillah
Published: September 2021

Abstract/Digest
Legal protection is very important for consumers. The government has provided legal protection for consumers as regulated in Article 4 of Law Number 8 of 1999 concerning Consumer Protection. Cosmetic consumers in Idi City use a lot of cosmetic products that are not registered with BPOM, as a result, skin damage occurs after the use is made by consumers. The people of Idi City as consumers of cosmetics are easily tempted by the effects of creams that can whiten the skin in a short period of time and the community does not have awareness of the legal protection rights they have.
This study aims to identify and explain the legal protection for consumers who use cosmetics that are not registered with BPOM, to find out and explain the obstacles to BBPOM Banda Aceh in legal protection of consumers using cosmetics that are not registered at BPOM and BBPOM Banda Aceh efforts in resolving barriers to consumers. cosmetic users who are not registered with BPOM.
This study uses a qualitative method with an empirical juridical approach. The data were obtained through library research and supported by field research. Data analysis was done descriptively (descriptive analysis).
Based on the results of the study, it is known that the implementation of legal protection for consumers has not been implemented optimally. Barriers to consumer protection are the lack of knowledge of consumers and business actors about regulations related to cosmetics. The efforts made are prevention strategies (socialization with the community), surveillance strategies and enforcement strategies.
It is suggested to the public to be wiser in choosing cosmetic products. Legal awareness for business actors in producing illegal cosmetics and carrying out their obligations as business actors in accordance with the laws and regulations and BPOM further enhances the cosmetic reducer in the market.
Keywords: Legal Protection, Consumers, Cosmetics.
Penegakan Syariat Islam di Aceh dalam Perspektif HAM
Authors: H Hamdani
Published: September 2021

Aceh merupakan satu-satunya provinsi di Indonesia yang diberikan keluasan oleh pemerintah pusat untuk mengatur kehidupan dan pembangunan di Aceh sesuai dengan Syariat Islam, pe-runtukan ini diperkuat dengan keluarnya UU Nomor 44 Tahun 1999 Tentang Keistimewaan Daerah Istimewa Aceh, UU Nomor 6 Tahun 2006 Tentang Pemerintah Daerah. Artinya secara hukum pemerintah Indonesia mengakui dan memberikan atau mengizinkan penerapan Syariat Islam di Aceh. Pada awal penerapan Syariat Islam di Aceh banyak mendapatkan tantangan dan rintangan baik secara internal, yaitu masyarakat yang tinggal di Aceh maupun eksternal yaitu dari luar Aceh juga dunia internasional dan pegiat HAM. Seiring perjalanan waktu pelaksanaan Syariat Islam di Aceh sudah diterima oleh semua pihak. Penegakkan syariat Islam di Aceh me-rupakan hak kebebasan dasar bukan saja tidak dilarang, melainkan dilindungi oleh Negara Indonesia. Legitimasi penegakan syariat Islam didasarkan pada HAM Internasional dan bebe-rapa Konvenan Hukum Internasional seperti Konvenan DUHAM 1948, konvensi mengenai hak-hak sosial, ekonomi, dan budaya (ICCESR) 1996 dan konvensi internasional tentang hak-hak sosial dan politik (ICCPR) 1996. Secara konstitusional UUD 1945 hasil amandemen 1999-2002 juga telah memperkuat argumen hukum internasional. Konsekuensinya negara dan pemerin-tah Republik Indonesia berkewajiban untuk tidak saja memberikan perlindungan dan perla-kuan yang adil dan proposional, melainkan juga memberikan dukungan terhadap penegakan syariat Islam di Aceh sebagai wahana yang memberikan penguatan terhadap Negara Kesatuan Republik Indonesia.
ANALISIS LAJU DOSIS SERAP MATERIAL NORM DI SEDIMEN DASAR LAUT BANDA, SULAWESI TENGAH
Authors: Siregar Ghifari Raihan Silam , Muslim Muslim , Ali Ali , Rochaddi Baskoro , Widada Sugeng
Published: September 2021

Material radioaktif alam atau NORM (naturally occurring radioactive materials) adalah material yang terkandung di bumi dan umumnya berasal dari beberapa sumber seperti pembakaran batubara, produksi migas, dan penambangan. Daerah pesisir laut banda, khususnya sepanjang Luwuk, Morowali, dan Kendari, Sulawesi Tengah, adalah daerah yang menjadi lokasi untuk beberapa kegiatan, seperti industri pertambangan, migas, dan pembangkit listrik. Tujuan dari penelitian ini adalah untuk mengkaji sebaran laju dosis serap material NORM pada sedimen dasar Laut banda, khususnya sepanjang Luwuk, Morowali, dan Kendari, Sulawesi Tengah, serta menganalisis nilainya terhadap baku mutu yang ada. Pengukuran laju dosis serap dari 226Ra, 232Th, dan 40K yang dilakukan pada 5 stasiun dan didapatkan hasil sebesar 52,53 nGy/jam; 355,75 nGy/jam; 45,88 nGy/jam; 131,86 nGy/jam; dan 35,38 nGy/jam. Hasil kajian yang didapatkan menunjukan bahwa sebaran nilai laju dosis serap dipengaruhi oleh kegiatan industri penghasil NORM yang dekat dengan lokasi stasiun pengukuran. Pola arus dan batimetri sendiri tidak terlalu berpengaruh dalam wilayah kajian ini. Tingkat bahaya laju dosis serap yang didapatkan masih berada <1 sehingga mengindikasikan bahwa risiko terhadap organisme di sekitar perairan tersebut tergolong rendah.
TINJAUAN TEKNIS PENEMPATAN SISTEM MOORING BUOY DAN OBU INA-TEWS DI DASAR LAUT
Authors: Irfan Muhamad , Haryadi Yudo , Haryanto Dwi , Rusdiansyah Alfi
Published: September 2021

Pengembangan teknologi sistem peringatan dini tsunami sudah dilakukan oleh BPPT sejak tahun 2006. Sejalan dengan perkembangannya, tahun 2021 BPPT mendapatkan tugas pemasangan sistem peringatan dini tsunami dengan platform buoy di laut lepas menggunakan wahana survei Kapal Riset Baruna Jaya BPPT. Metode penempatan platform buoy di dasar laut harus direncanakan secara baik, mulai dari desain, spesifikasi teknis, rencana operasi, dan teknis pelaksanaan yang sesuai dengan prosedur standar. Hal ini cukup penting mengingat platform buoy dibangun dengan biaya yang cukup besar, dan biaya operasi survei yang besar juga, sehingga sistem ini harus ditempatkan di laut lepas secara akurat dengan menggunakan teknologi survei kelautan yang handal. Selain itu, kondisi cuaca juga harus diperhatikan dengan baik karena lokasinya adalah di samudera lepas. Kondisi arus laut juga harus diketahui secara akurat agar sistem mooring buoy bisa tegak terpasang dengan baik, dan sistem OBU mampu mendeteksi tinggi muka laut dan mengirimkannya ke buoy permukaan, selanjutnya dikirimkan ke pusat data Ina-TOC di Jakarta via satelit.
Genogeography of norway spruce (Picea abies (L.) Karst.) according to the analysis of cytoplasmic DNA
Authors: Padutov V. E. , Kagan D. I. , Ivanovskaya S. I. , Baranov O. Yu. , Markevich T. S.
Published: September 2021

Norway spruce (Picea abies (L.) Karst.) is one of the main forest-forming species in Belarus. It plays important economic, ecological and social roles. The spruce forest of the region is characterized by a complex history of the formation of its population genetic structure. The aim of this study was the genogeographic analysis of P. abies populations and the description of regional features of its gene pool in Belarus. Molecular genetic analysis of microsatellite (SSR) loci of chloroplast DNA and mt15-D02 locus of mitochondrial DNA of Norway spruce was carried out for samples from 57 naturally originated forest stands. We identified 19 allelic variants of the Pt63718, Pt26081, Pt71936 cpDNA loci and two allelic variants of mt15-D02 mtDNA. The geographical distribution of the alleles has been described and the regional features of the genogeographic differentiation of the spruce forests have been considered. The southern border of the continuous distribution area of P. abies and its island localities lie in the south of Belarus (Brest and Gomel regions). The frequency of occurrence of individual allelic variants of cpDNA SSR loci has the most pronounced deviations from the average values for the whole country in those regions. Analysis of cpDNA showed the presence of certain regional features of the genogeographic structure of the spruce forest in the “south-north” and “west-east” directions. According to mitochondrial DNA analysis higher concentration of P. abies trees of southern (Carpathian) origin is observed in the southwest of Belarus. On the contrary northern (Boreal) origin dominates in the rest of the country. The results of performed genogeographic analysis of Norway spruce populations can serve as a basis for improving the forest seed zoning of the tree species.
Extraction sample preparation for chromatographic determination of residual quantities of acidic penicillins in milk
Authors: Polonevich A. G. , Leschev S. M. , Palianskikh A. I. , Belyshava L. L.
Published: September 2021

The distribution of six acid-type penicillins (penicillin G, penicillin V, oxacillin, cloxacillin, nafcillin, dicloxacillin) in the extraction systems of chloroform–aqueous solutions of ammonium sulfate was studied. The reported distribution coefficients values of penicillins demonstrated the effectiveness of using ammonium sulfate as a salting-out agent. Based on the data obtained, a procedure for milk sample preparation was developed for the quantification of the residual content of six acid-type penicillins.
Eighteen-year results of treatment of uveal melanoma using Ruthenium-106 + Rhodium-106 brachytherapy
Authors: Naumenko L. V. , Zhyliayeva K. P. , Evmenenko A. A. , Zherka I. Yu. , Krasny S. A.
Published: September 2021

The objective of the study was to evaluate the results of Ruthenium-106 (106Ru) + Rhodium-106 (106Rh) brachytherapy in uveal melanoma (UM) patients.The data for the period 2001–2018 were taken from the Belarusian Cancer Registry and medical records of patients with clinically diagnosed uveal melanoma who received treatment at the N. N. Alexandrov National Cancer Centre of Belarus. A total of 383 patients were included in the study. 106Ru + 106Rh β-ophthalmic applicators were used for brachytherapy (BT). The calculated dose to the tumor apex was 120–130 Gy, while the reduced 100–110 Gy was administered to tumors close to the optic nerve. To analyze the treatment outcomes, patients were divided into three groups based on a basal diameter of a tumor.Out of a total 383 patients, complete tumor resolution was observed in 282 (73.6 %), tumor stabilization was present in 76 (19.8 %). Continued tumor growth and tumor relapse were observed in 34 (9.13 %) and 50 (13.05 %) patients, respectively. 59 (15.1 %) patients underwent enucleation. The metastatic disease developed in 47 (12.3 %) cases. BT adverse effects were observed in 21.3 % cases. The relapse-free survival in the group of patients with a basal tumor diameter of up to 9 mm was 76.0 ± 6.3 %, which was higher than that in the groups with a large basal diameter (p = 0.002). Over a 15-year follow-up period, almost half of the patients (52.2 ± 15.6 %) with a tumor base of more than 12 mm relapsed.Considering the high rates of the continued tumor growth during treatment in patients with a basal tumor diameter of more than 12 mm, combined therapy must be used in this group.
Epidemiological features of malignant mesothelioma in the Republic of Belarus
Authors: Hutsich K. A. , Levin L. F.
Published: September 2021

Based on the data of the Belarusian Cancer Register for 2000–2019 the dynamics and structure of incidence of mesothelioma in the Republic of Belarus are studied. We calculated incidence rates, age-standardized incidence rates, taking into account the gender and place of residence of patients, cumulative risk. The analysis of the structure was carried out both for the whole population and separately for men and women, as well as for the urban and rural population.We detected that the incidence rates of malignant mesothelioma in the Republic of Belarus are significantly lower than those in the Western Europe region and the Central and Eastern European region. For the period from 2000 to 2019 the dynamics of the incidence rates of mesothelioma in the Republic is characterized by a moderate tendency to decrease, and in the general structure of the incidence rate both among men and among women, pleural mesothelioma is the dominant localization. The population of regions where asbestos-cement manufacturing is located has no higher risk of developing malignant mesothelioma in comparison with population levels.The estimated incidence of mesothelioma in men is 2 times higher than the incidence of women, and this excess is independent of age differences between these two populations. The highest incidence rates for men are observed at the age of 75–79 years, while the peak incidence for men living in the city falls at the earlier age – 70–74 years. Among women living both in the city and in rural areas, the peak incidence falls at the age of 80–84 years.
Use of laparocentesis in the treatment of ascites in patients with liver cirrhosis
Authors: Mahiliavets E. V. , Bozhko Y. N. , Mahiliavets O. N.
Published: September 2021

Ascites occurs in about 60 % of patients with cirrhosis within 10 years of diagnosis. Laparocentesis is the preferred first-line therapy in patients with cirrhosis and massive tense ascites, allowing more than 5–6 liters of ascitic fluid to be removed at one time. The search for informative prognostic factors and the development of a method for predicting unfavorable outcomes of repeated laparocenteses in patients with ascites are relevant to timely refer this contingent of patients to perform TIPS.The purpose of the study was to develop and evaluate the diagnostic significance of a model for determining the probability of unfavorable outcomes of laparocentesis in patients with ascites on the background of liver cirrhosis.The results of treatment of 99 patients with the ascitic syndrome associated with intrahepatic portal hypertension were studied. The multiple regression analysis using the binary response logit model was carried out to calculate the prediction models. The analysis of the treatment results of patients with liver cirrhosis and ascites by the laparocentesis method revealed a number of factors that influence the onset of an unfavorable outcome. 2 models with the inclusion of initial variables are the most promising for forecasting. Model A includes: patient weight, serum-ascites total protein gradient, hyponatremia; model B: MELD-Na score, serum-ascitic total protein gradient, patient weight. The developed prediction method is highly informative, effective, easily applicable, and can be widely used in clinical practice.The ability to predict an unfavorable outcome in patients with portal hypertension and ascites after laparocentesis allows for a personalized approach in the process of timely selection of more effective, but also more expensive treatment methods, such as TIPS, which will help us to increase the therapy effectiveness and the survival of this cohort of patients.
Relapse risk factors during allogeneic stem cell transplantation in children, adolescents and young adults with acute lymphoblastic leukemia
Authors: Prudnikau D. V. , Kirsanava N. P. , Mareika Yu. E. , Minakovskaya N. V. , Aleinikova O. V.
Published: September 2021

More than 20–25 % of patients with acute leukemia underwent transplantation of HSC from HLA-identical sibling or unrelated donor had relapse.Therefore, the purpose of this study was to evaluate the influence of different factors on the risk of post-transplantation relapse in children and teenagers with acute lymphoblastic leukemia (ALL).The gender, the age of a donor at the time of transplantation; the gender, the age of a recipient at the time of transplantation; the type, the number of relapses of previous HSCTs; the type of conditioning; the type of transplantation; the source of stem cells; transplant parameters; the acute (aGVHD) and chronic (cGVHD) graft-versus-host disease or its absence; the KIRalloreactivity of donor NK cells were estimated as risk factors for the disease relapse in our study.We established that the recipient’s age of less than 4 years at the time of transplantation (p = 0.0042); the time of relapse (very early and early) (p = 0.0047); the absence of aGVHD (p = 0.0183) or cGVHD (p = 0.0384) have been the important factors for the disease relapse of patients with ALL after allogeneic HSC transplantation.
Methodology and practice of building a new end-to-end corporate governance system for the agro-industrial complex
Authors: Gusakov E. V.
Published: September 2021

A conceptual model of the organization and functioning of the agro-industrial complex management system as a mega-cluster formation has been constructed, which includes four main blocks: organizational, economic, legal and institutional, which contain their inherent instruments and levers of regulation. Based on the above, the definition of the management model of the agro-industrial complex as a mega-cluster organization has been formulated. In development, an appropriate definition of the organizational and economic model of corporate governance of the agro-industrial complex as a mega-cluster is given. A set of factors that affect the management system in the agro-industrial complex has been established, and their brief interpretation is given. It has been established that in the modern practice of the agro-industrial complex, several main groups of models can be distinguished, typical for all levels of management: A. Incomplete – not all levels of management are covered; B. Traditional – all functions and organizational structures can be present in the management system; C. Market models – correspond to the specifics of management in market conditions; D. Innovative – based on combining the best aspects of all known models. On this basis, it was revealed that at present, the solution of most of the problems of the agro-industrial complex is possible, first of all, through the development of an end-to-end system of corporate management of agro-industrial production as a megacluster infrastructure.
The complex interplay in the regulation of cardiac pathophysiologic functionalities by protein kinases and phosphatases
Authors: Chrysanthus Chukwuma Sr
Published: September 2021

Protein phosphorylation regulates several dimensions of cell fate and is substantially dysregulated in pathophysiological instances as evident spatiotemporally via intracellular localizations or compartmentalizations with discrete control by specific kinases and phosphatases. Cardiovascular disease manifests as an intricately complex entity presenting as a derangement of the cardiovascular system. Cardiac or heart failure connotes the pathophysiological state in which deficient cardiac output compromises the body burden and requirements. Protein kinases regulate several pathophysiological processes and are emerging targets for drug lead or discovery. The protein kinases are family members of the serine/threonine phosphatases. Protein kinases covalently modify proteins by attaching phosphate groups from ATP to residues of serine, threonine and/or tyrosine. Protein kinases and phosphatases are pivotal in the regulatory mechanisms in the reversible phosphorylation of diverse effectors whereby discrete signaling molecules regulate cardiac excitation and contraction. Protein phosphorylation is critical for the sustenance of cardiac functionalities. The two major contributory ingredients to progressive myocardium derangement are dysregulation of Ca2+ processes and contemporaneous elevated concentrations of reactive oxygen species, ROS. Certain cardiac abnormalities include cardiac myopathy or hypertrophy due to response in untoward haemodynamic demand with concomitant progressive heart failure. The homeostasis or equilibrium between protein kinases and phosphatases influence cardiac morphology and excitability during pathological and physiological processes of the cardiovascular system. Inasmuch as protein kinases regulate numerous dimensions of normal cellular functions, the pathophysiological dysfunctionality of protein kinase signaling pathways undergirds the molecular aspects of several cardiovascular diseases or disorders as related in this study. These have presented protein kinases as essential and potential targets for drug discovery and heart disease therapy.
Two Egyptian Heart-Scarabs from Sicily and a Parallel from Berlin
Authors: Laroche Claude , Rosati Gloria
Published: September 2021

Two Egyptian heart-scarabs, both connected to the city of Cefalù, are presented here: the first one, at Palermo, Museo Archeologico Regionale, was published in 1942 by E. Bacchi, as one of the few heart-scarabs found outside Egypt, on the rock of Cefalù. Its text has been checked and some new readings are proposed. Inscribed for a Chantress of Bastet, it shows a peculiar decoration on the first register, looking like a lunette, then the traditional beginning of Chapter 30B of the Book of the Dead, typical for heart-scarabs, combined with a rare variant. It had remained a unicum until July 2020, when a parallel in the Berlin Museum came to our knowledge, and this is published here as well: the same decoration in the first register and the same text, although shorter. Mainly on the base of prosopographical data, a date to the Twenty-second Dynasty seems appropriate for the Berlin scarab, and consequently for the one in Palermo, which could even belong to a member of the same family. The owner of the scarab in Berlin shows a set of priestly titles that are typical of Per-Sopdu/Saft el-Henna, which therefore may be an indication of its origin. The second “Sicilian” scarab, held at Cefalù itself in the collection of Enrico Pirajno Baron of Mandralisca, after whom the Museum is named, is unpublished. Its owner was another Chantress, serving Amun-Re, and nearly contemporary: it is to be dated to the early Third Intermediate Period, Twenty-first – Twenty-second Dynasty. In the Appendix at the end, notes and remarks on the provenance of the two scarabs in Sicily, documenting mainly the discovery of the Palermo scarab.

ملخص

تظهر هنا قطعتان تمائم جعران القلب المصرية، ترتبط كلاهما بمدينة تشِفالو: القطعة الأولى، معروضة في المتحف الأثري الإقليمي في مدينة باليرمو، نُشِر عنها في عام 1942 من قبل إ. باكي كاحدى جعران القلب الفرعونية النادرة التي وُجدت خارج الأراضي المصرية. تَحدّث المؤلفون عن ظروف اكتشافها، تحققوا مرة أخرى من النص واقترحوا بعض القراءات الجديدة. كانت تملكها مطربة باستيت، وهو لقب لم يتم تناوله  ضمن المنشورات الحالية لمجموعة جعران القلب. إنها على غرار جعران القلب التي لم ينشر عنها ومحفوظة في برلين، من المدهش أنها تنتمي على الأرجح إلى شخص من نفس أفراد تلك العائلة، تعود غالباً إلى تاريخ الأسرة الثانية والعشرين. كانت تنتمي جعران برلين إلى والد الإله أنوبيس وإلى الكاهن بتاح-ون، وهو لقب خاص لبير-سوبدو / سفت-الحنا. تميمة جعران القلب الثانية الموجودة في جزيرة صقلية، محفوظة في نفس موقع تشِفالو، في متحف ماندراليسكا، لم يُنشر عنها أي مقال: مرة أخرى شاءت الظروف أن تكون مالكتها مغنية، لكنها كانت  تخدم آمون رع. تعود القطعة أيضاً إلى أوائل فترة الإنتقال الثالثة.
Investigation of the Prevalence of Cerebral Transverse Venous Sinus Stenosis in Idiopathic Intracranial Hypertension
Authors: YİLMAZ CAN Fatma , PANPALLI ATEŞ Mehlika
Published: September 2021

Purpose: Idiopathic intracranial hypertension (IIH) is an increase in intracranial pressure with a normal cerebrospinal fluid (CSF) composition that is not due to a secondary cause. The existence of cerebral transverse venous sinus stenosis and changes in venous outflow in IIH has recently gotten a lot of attention, and this situation is becoming increasingly important in terms of diagnosis and treatment plan.

This study aimed to investigate how frequent cerebral transverse venous sinus stenosis is in patients with IIH.

Methods: The demographic profile of 27 patients with IIH who were followed up in the hospital's neurological headache outpatient clinic and the occurrence of cerebral transverse venous stenosis on cranial magnetic resonance venography (MRV) were studied. Considering the pre-diagnosis of cerebral venous thrombosis (SVT), patients who underwent magnetic resonance venography (MRV) and whose SVT was ruled out during their follow-up were included as the control group. This control group consisted of 48 patients diagnosed with migraine, tension-type headache (TTH), and new-onset daily persistent headache.

Results: When MRVs were investigated, cerebral transverse venous sinus stenosis was detected in %55.6 (n=15) of IIH patients and 25% (n=12) of the control group (p = 0.017).

Conclusions: The frequency of cerebral transverse sinus stenosis in MRV of patients diagnosed with IIH was found to be significantly higher in this study than in the control group. These findings indicated that cerebral transverse venous stenosis can play a role in the progression of IIH.
In Silico MLST, SCCmec and SPA Typing OF Human MRSA Strains and Determination of Antimicrobial Resistance Genes
Authors: DEMİRCİ Mehmet , YIĞIN Akin , EKİCİ Seda
Published: September 2021

Objectives: The incidence of MRSA still remains an important public health problem. This study aimed to perform in silico analysis of MLST, SCCmec, spa type, evolutionary similarity, and whole-genome sequencing (WGS) based antimicrobial susceptibility testing by using genomic data of MRSA strains isolated from human infections in different countries.
Methods: WGS data of 30 MRSA strains were obtained as etiological agents were download from NCBI. Phylogeny analysis with large data was performed via CSI Phylogeny online software. SCCmec, MLST, and spa typing were performed using the software at the Center for Genomic Epidemiology. ResFinder 4.0 was used to perform WGS based antimicrobial susceptibility testing.
Results: After in silico analysis of 30 MRSA strains, 14 different spa types, 11 different sequence types, and 9 different SCCmec types were detected. T037, ST239, and SCCmec_type_III(3A) were the most detected spa, MLST, and SCCmec types. WGS based antimicrobial susceptibility testing results were analyzed, 28, 27, and 26 out of 30 MRSA strains carrying aminoglycoside tetracycline and fluoroquinolone resistance genes respectively.
Conclusion: Our in silico analysis results, we found that similar typing profiles could be observed in the strains in different geographical locations, and certain types of spa, MLST, and SCCmec can coexist.
Deradikalisasi Narapidana Teroris melalui Individual Treatment
Authors: Yuliyanto Yuliyanto , Michael Donny , Utami Penny Naluria
Published: September 2021

Radikalisme yang dilakukan oleh teroris, baik individu maupun kelompok, jika tidak dilakukan penanganan yang serius, dampak negatifnya akan semakin meluas. Penelitian ini bertujuan untuk mengetahui dan menganalisa penerapan perlakuan individu terhadap narapidana teroris. Penelitian ini menggunakan pendekatan yuridis empiris. Data primer dalam penelitian ini diperoleh melalui wawancara mendalam dengan sejumlah pemangku kepentingan. Sedangkan, data sekunder diperoleh melalui regulasi terkait pembinaan narapidana teroris. Studi ini menemukan bahwa deradikalisasi narapidana teroris melalui perlakuan individu dilakukan dengan pembinaan kepribadian yang meliputi pembinaan kesadaran beragama, kesadaran berbangsa dan bernegara, kesadaran hukum, dan penyuluhan. Pembinaan dilakukan secara individu di ruang / sel penjara. Pemilahan narapidana dalam rangka penempatan didasarkan pada penilaian tingkat risiko setiap narapidana. Ruang lingkup dalam penelitian ini adalah program pembinaan kepribadian terhadap narapidana teroris melalui perlakuan individu. Melalui penelitian ini, penulis ingin memberikan kontribusi kepada Kementerian Hukum dan HAM, khususnya Direktorat Jenderal Pemasyarakatan untuk lebih meningkatkan kualitas pembinaan terhadap narapidana teroris; dan membangun kerjasama dengan instansi lain dalam menangani narapidana teroris di Indonesia.
Gagasan Konstitusi Pangan: Urgensi Pengaturan Hak Atas Pangan Warga Negara dalam Amandemen Kelima UUD 1945
Authors: Saifulloh Putra Perdana Ahmad
Published: September 2021

Berdasarkan potret buruk pemenuhan hak atas pangan, maka penelitian ini mengusulkan penguatan norma jaminan perlindungan dan pemenuhan hak atas pangan dalam rencana Amandemen Kelima UUD 1945. Tujuan penelitian ini agar dimuatnya hak atas pangan sebagai materi muatan konstitusi. Penelitian ini menggunakan metode penelitian hukum normatif dengan pendekatan perundang-undangan, dan konseptual. Hasil penelitian ini: UUD 1945 mengalami kelemahan, terutama pengaturan dalam jaminan, pemenuhan dan perlindungan hak atas pangan yang tidak secara eksplisit diatur. Yang diperkuat dengan fakta-fakta beberapa kasus krisis pangan di Indonesia memberikan justifikasi bahwa eksistensi hak atas pangan urgen dimuat dalam Amandemen UUD 1945 Kelima untuk memperkuat hak atas pangan dalam konstitusi dan amandemen konstitusi juga memberikan jaminan ketersediaan lahan pertanian demi mewujudkan ketahanan pangan. Dalam amandemen tersebut, Penulis menilai memberikan kepastian hukum kepada warga negara agar haknya di bidang pangan lebih terjamin. Sehingga bisa dikatakan bahwa UUD 1945 adalah Konstitusi Pangan.
Terapi Psikososial Pada Osteoartritis Di Komunitas
Authors: Pratiwi Arum , Muhlisin Abi , Rahayu Umi Budi
Published: September 2021

Program kemitraan komunitas ini dilakukan dengan tujuan membimbing, dan melatih para mitra yaitu kelompok penderita osteoartritis (OA) dan masyarakat yang berisiko untuk meningkatkan kualitas hidup. Metode yang digunakan adalah bersama dengan mitra yaitu kader kesehatan dan masyarakat, mengidentifikasi kelompok sasaran dan menciptakan home based untuk pusat terapi. Tim kemitraan ini melatih para penderita OA dengan teknik relaksasi, senam osteoarthritis, dan pendidikan kesehatan mengenai diet dan kontrol emosional. Sebelum kegiatan dilakukan, tim kemitraan melakukan pemerikasaan laboratorium asam urat dan gula darah sewaktu. Alat pemeriksaan yang digunakan adalah easy touch dan stik, media komunikasi yang digunakan adalah modul, leaflet, audiovisual, dan poster. Jumlah peserta pengabdian ini adalah 100 orang ysng kemudian teridentifikasi OA menjadi 52 orang. Hasil kegiatan ini terdiri dari gambaran hasil asam urat, gula darah, gambaran nyeri, tingkat pengetahuan yang meningkat pada mitra yaitu rata-rata nilai pre-test 55,27 menjadi 72,10; Peningkatan ketrampilan mitra yaitu mampu memperagakan senam OA dan teknik relaksasi secara mandiri.Kata Kunci: Pemberdayaan masyarakat, pelatihan, pendampinganPsychosocial Therapy for Osteoarthritis in the CommunityABSTRACTThe purpose of the community partnership program was guiding of partner to train them who are groups of osteoarthritis (OA ) sufferers and communities that risk to improve quality of life . The method of this activity including built home based therapy centers and then trained OA sufferers used relaxation techniques, osteoarthritis exercises, and health education on diet and emotional control. Before the activity was carried out, the partnership team conducted a laboratory test of uric acid detection and blood sugar level. The examination was used easy touch tools and sticks . the medium of display was used modules, leaflets, audiovisual, and posters. The number of participants of this activity was initially 100 people, next, was identified 52 participant with OA. The results of this activity consisted of a description of the results of uric acid level, blood sugar level, a description of pain, an increased level of knowledge at partners that the average score of 55.27 to 72.10; Enhancing partner skills is able to demonstrate OA exercises and relaxation techniques independently.Keywords: Community empowerment, training program, coaching, mentoring.
Perbaikan mutu produk baby fish nila krispi di Kelompok Tani Karya Mina Utama, Rowo Jombor, Klaten, Jawa Tengah
Authors: Ratnaningsih Nani , Rahayu Tutiek , Mujiyono Mujiyono
Published: September 2021

Kelompok Tani Karya Mina Utama merupakan kelompok produsen baby fish nila krispi di Rowo Jombor dengan mutu produk tidak konsisten, kemasan dan labeling sangat sederhana. Tujuan kegiatan pengabdian kepada masyarakat ini adalah memperbaiki mutu dan kemasan produk baby fish nila krispi sehingga dapat meningkatkan branding produk dan pangsa pasar. Metode kegiatan dilakukan dengan diskusi bersama, penyusunan standar proses produksi, pendampingan penerapan standar proses produksi, serta perbaikan kemasan dan label. Hasil kegiatan menunjukkan mutu produk baby fish nila krispi yang diproduksi oleh Kelompok Tani Karya Mina Utama, Desa Krakitan, Klaten dapat ditingkatkan dengan perbaikan standar proses produksi, kemasan dan labeling produk. Standar proses produksi nila krispi meliputi pemilihan anak ikan, pembersihan isi perut, pembelahan, pencucian, perendaman dalam bumbu, pelapisan dengan tepung beras dan tapioka, penggorengan, penirisan minyak dengan spinner, dan pengemasan. Produk dikemas dengan kantong plastik pouch (200 gram) dengan label berisi brand/merk, nama produk, komposisi, berat bersih, informasi gizi, nomer P-IRT, nomer sertifikat halal, tanggal kadaluwarsa, nama dan alamat produksi, dan binaan. Produk nila krispi dari kegiatan ini dapat mencantumkan klaim kaya kalsium dan sumber protein sehingga berpotensi sebagai oleh-oleh khas Rowo Jombor.Kata Kunci: baby fish nila krispi; mutu produk; pendampingan; Rowo Jombor Improving the quality of crispy tilapia baby fish products at the Karya Mina Utama Farmers Group, Rowo Jombor, Klaten, Central Java ABSTRACTKarya Mina Utama Farmer Group is a producer of baby tilapia crisp from Rowo Jombor with inconsistent product quality and very simple in packaging and labeling. The purpose of community service activities was to improve the quality and packaging of baby tilapia crisp for increasing the brand product and market. The activities were done by focus group discussions, preparation of standards of production process, assistance in applying the standards of production process, and improvement of packaging and labels. The results showed that the quality of baby tilapia crisp produced by the Karya Mina Utama Farmer Group can be increased by improving the production process, packaging and labeling. Standard of production process consisted of selecting baby fish, cleaning stomach contents, cleavage, washing, soaking in seasonings, coating with rice flour and tapioca, frying, draining oil with spinner, and packaging. The product is packaged in a plastic bag pouch (200 grams) with a label containing the brand, product name, composition, net weight, nutritional information, P-IRT number, halal certificate number, expired date, name and address of production, and support team. Baby tilapia crisp can use the claim of rich in calcium and source of protein so that they have the potency as the special souvenir from Rowo Jombor.Keywords: baby tilapia crisp; product quality; assistance; Rowo Jombor