bluuebunny/crossref_metadata_2025 huggingface dataset:
The Review of The Effects of Realistic Mathematics Education on Students' Academic Achievement in Turkey: A Meta-Analysis Study
Authors: ÖKSÜZ Cumali , ESER Mehmet Taha , GENÇ Galip
Published: December 2022

Realistic Mathematics Education (RME) includes identifying and solving problems. Besides, it is an effort to organize a case, reorganize it according to new ideas, and concretize and rediscover the case to understand it better. This research aims to determine the effect of RME-based teaching against traditional methods, develop a general opinion, and contribute to the literature. In the study, the meta-analysis method was used to synthesize the results of independent experimental studies examining RME's effect on academic achievement. The data set of the research was created in September 2022. Necessary searches were carried out within the ULAKBİM TR Index, YÖK Thesis, ERIC and Web of Science databases. As a result of these searches, 54 studies met the selection criteria to be included in the meta-analysis. The random-effects model was used in the research. As a result of the analysis, the calculated effect sizes were all positive. In the light of this finding, it has been concluded that in all studies, RME-based teaching was more effective than traditional methods on students' academic achievement in mathematics. A moderator analysis was also carried out to determine whether the effect sizes differed statistically significantly according to the variables "publication type, sample size, and educational stage." As a result of the moderator analysis, it was concluded that all moderator variables obtained from the GME-based teaching practices significantly affected the combined effect size.
A Study on Parents' Emotion Regulation Skills, Self-Awareness, and Cognitive Flexibility Levels
Authors: DOĞAN LAÇİN Betül Gökçe , TURP Hurizat Hande
Published: December 2022

Individuals' cognitive flexibility, their capacity to regulate their emotions, and their ability to be aware of the present moment will positively influence the way they behave toward themselves and their environment. It is considered that parents with these characteristics will exhibit behaviors that influence future generations largely in a positive way. The research aims to test a hypothetical model developed based on the literature to determine the factors affecting the cognitive flexibility of parents. The study group for the research consists of 351 parents with children in various age groups who are attending preschool, primary school, secondary school, or high school. The Cognitive Flexibility Inventory, Emotion Regulation Questionnaire, and Interpersonal Mindfulness in Parenting Scale were utilized as data collection tools in this study. The research was carried out with the relational screening model. Structural equation modeling was used for the analysis of the data. In the model, where cognitive flexibility was accepted as a predicted variable, emotion regulation skills and mindfulness demonstrated a positive relationship. Besides, mindfulness displays a positive relationship with cognitive flexibility.
Impelementasi Metode Simpleks Untuk Optimasi Penjualan Produk UKM Pada Masa Pandemi
Authors: Rumetna Matheus Supriyanto , Lina Tirsa Ninia , Salawe Diosphyros , Irianti Rezky , Buku Gabriel Valentino , Lokollo Sonia , Walalayo Titalae , Sauyai Yetti , Wayega Ferdinandus , Karepouwan Vincent
Published: December 2022

Small and Medium Enterprises (SMEs) are one of the businesses that have an important role in developing the economy in Indonesia. However, when the Covid-19 pandemic hit many SME players who had difficulty optimizing business activities. The Covid-19 pandemic is a major threat in all fields. Mrs. Martina's SME is one of the SMEs that experienced a decline in profits during the Covid-19 pandemic. Some of the obstacles faced by Mrs. Martina are costs, transportation and distance. For the development of Mrs. Martina's business, it is necessary to take steps to increase the profit from the sale. These steps must use a technique or method so that they have a more accurate estimate in the calculation. One of the methods that can be used is the Simplex method which is part of the Linear Program. This research has the main objective of helping SMEs, especially those owned by Mrs. Martina, in terms of optimizing sales results in order to increase profits. This research also utilizes information technology, namely POM-QM software, to make it easier to determine and calculate the maximum profit obtained from each production carried out by Mrs. Martina's SME within one week quickly and accurately. The results obtained are used as reference material or benchmarks for SMEs in terms of making decisions for business development.
The rationale for heterogeneous inclusion of ecosystem trends and variability in ICES fishing opportunities advice
Authors: Trenkel VM , Ojaveer H , Miller DCM , Dickey-Collas M
Published: December 2022

Incorporation of ecosystem information into fish stock assessments and management advice, a cornerstone of delivering ecosystem-based fisheries management (EBFM), occurs often implicitly, faces multiple challenges, and remains often unquantified in terms of scope and scale. This paper provides a comprehensive overview of the inclusion of ecosystem trends and variability in ICES fishing opportunities advice in the Northeast Atlantic, by covering 87% of stocks corresponding to 99% of landings. Just under 50% of all stock assessments considered ecosystem information and the majority of management strategy evaluations did so in at least one way. Almost 73% of the data-rich stocks incorporated ecosystem trends and variability in at least one way, and almost 55% of short-term forecasts did so. Stock (individual growth rate) and fisheries (landings) characteristics largely explained the observed patterns of incorporation of ecosystem information into advice, with pelagic species and stocks with higher landings having higher instances of incorporation. Early stages of the advice process (closer to data analysis and methods development) had greater inclusion of ecosystem information, though this inclusion was generally implicit and not explicit, e.g. based on a hypothesis of environmental influence on stock dynamics. Moving towards explicit instructions and routine documentation of the inclusion of ecosystem information in fishing opportunities advice will accelerate the path to the EBFM in a consistent and transparent manner.
Byssal thread attachment and growth are not correlated across gradients of temperature and food availability for two congeneric mussel species
Authors: Roberts EA , Carrington E
Published: December 2022

Anthropogenic warming and natural climate variability affect global patterns of seawater temperature and marine primary productivity and affect organism survival, growth, and physiology. Mussels are ecosystem engineers that utilize byssal thread structures to attach to hard substrate, a strategy key to survival in wave-swept rocky shore environments. Byssal thread production varies according to season and environmental conditions, and temperature and food availability may influence the production of these structures by affecting energy limitation. Mytilus trossulus and M. galloprovincialis are congeneric mussel species in the Northeast Pacific with cold- and warm-adapted thermal tolerances, respectively. First, we hypothesized that temperature has opposing effects on growth rates of the 2 species. Second, we hypothesized that either (1) byssal thread production is positively correlated with growth rate (the ‘production’ hypothesis), or (2) there is a trade-off between growth and byssal thread production, and resources are allocated first to byssal thread production rather than growth. Under this ‘trade-off’ hypothesis, we predicted no relationship between growth rate and byssal thread production. We manipulated seawater temperature and food availability and quantified mussel performance in terms of survival, growth, and byssus attachment. Across all treatment combinations, we found that M. galloprovincialis had positive shell and tissue growth and M. trossulus had minimal shell growth and a loss in tissue mass. Temperature had opposing effects on each species; temperature increased shell growth of M. galloprovincialis but increased tissue loss of M. trossulus. Temperature did not affect byssal thread production, and there was no significant relationship between byssal thread quality or quantity and shell or tissue growth across the temperature and food gradient for either species. Our results suggest that energy allocation is prioritized towards byssal thread production over growth.
Simvastatin and dehydroepiandrosterone sulfate effects against hypoxic pulmonary hypertension are not additive
Authors: Krása K , Vajnerová O , Ďurišová J , Minaříková M , Miková D , Srbová M , Chalupský K , Kaftanová B , Hampl V
Published: December 2022

Pulmonary hypertension is a group of disorders characterized by elevated mean pulmonary artery pressure (mPAP) and pulmonary vascular resistance. To test our hypothesis that combining two drugs useful in experimental pulmonary hypertension, statins and dehydroepiandrosterone sulfate (DHEA S), is more effective than either agent alone, we induced pulmonary hypertension in adult male rats by exposing them to hypoxia (10%O2) for 3 weeks. We treated them with simvastatin (60 mg/l) and DHEA S (100 mg/l) in drinking water, either alone or in combination. Both simvastatin and DHEA S reduced mPAP (froma mean±s.d. of 34.4±4.4 to 27.6±5.9 and 26.7±4.8 mmHg, respectively), yet their combination was not more effective (26.7±7.9 mmHg). Differences in the degree of oxidative stress (indicated by malondialdehydeplasma concentration),the rate of superoxide production (electron paramagnetic resonance), or blood nitric oxide levels (chemiluminescence) did not explain the lack of additivity of the effect of DHEA S and simvastatin on pulmonary hypertension. We propose that the main mechanism of both drugs on pulmonary hypertension could be their inhibitory effect on 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase, which could explain their lack of additivity.
Blood pressure reduction induced by chronic intracerebroventricular or peroral clonidine administration in rats with salt-dependent or angiotensin II-dependent hypertension
Authors: Zicha J , Řezáčová L , Behuliak M , Vaněčková I
Published: December 2022

The agonists of α2-adrenergic receptors such as clonidine, rilmenidine or monoxidine are known to lower blood pressure (BP) through a reduction of brain sympathetic outflow but their chronic antihypertensive effects in rats with low-renin or high-renin forms of experimental hypertension were not studied yet. Moreover, there is no comparison of mechanisms underlying BP reduction elicited by chronic peroral (po) or intracerebroventricular (icv) clonidine treatment. Male salt-sensitive Dahl rats fed 4% NaCl diet and Ren-2 transgenic rats were treated with clonidine administered either in the drinking fluid (0.5 mg/kg/day po) or as the infusion into lateral brain ventricle (0.1 mg/kg/day icv) for 4 weeks. Basal BP and the contributions of renin-angiotensin system (captopril 10 mg/kg iv) or sympathetic nervous system (pentolinium 5 mg/kg iv) to BP maintenance were determined in conscious cannulated rats at the end of the study. Both peroral and intracerebroventricular clonidine treatment lowered BP to the same extent in either rat model. However, in both models chronic clonidine treatment reduced sympathetic BP component only in rats treated intracerebroventricularly but not in perorally treated animals. In contrast, peroral clonidine treatment reduced angiotensin II-dependent vasoconstriction in Ren-2 transgenic rats, whereas it lowered residual blood pressure in Dahl rats. In conclusions, our results indicate different mechanisms of antihypertensive action of clonidine when administered centrally or systemically.
Perspektif Xenotransplantasi (Transplantasi Organ Hewan ke Manusia) Ditinjau dari Hukum Islam
Authors: Nazar Muhamad , Sensu La , Sjaiful Muhammad
Published: December 2022

Perkembangan teknologi di bidang kesehatan berkembang sangat pesat termasuk pada metode transplantasi. Transplantasi menjadi pilihan yang dapat memperpanjang usia harapan hidup manusia dalam bentuk transfer organ. Tetapi, terdapat pula hambatan berupa tidak sedikit yang harus kehilangan nyawa akibat waktu tunggu cukup lama/antrean dalam menemukan organ manusia yang sesuai. Xenotransplantasi merupakan jenis transplantasi dari hewan ke manusia yang dapat dijadikan alternatif serta telah diuji coba di beberapa negara. Tulisan ini bertujuan untuk menjelaskan pembahasan mengenai xenotransplantasi ditinjau dari aspek filosofis, yuridis serta hukum Islam. Metode yang digunakan adalah penelitian deskriptif. Hasil penelitian ini menunjukkan bahwa dalam aspek filosofis, xenotransplantasi dapat digunakan sebagai pilihan kesembuhan seutuhnya atau sebagai media sementara hingga menemukan organ manusia yang tepat. Aspek yuridis yakni pemerintah Indonesia belum mengatur regulasi resmi terkait xenotransplantasi, tetapi terdapat referensi sebelumnya mengenai transplantasi yakni UU No. 36 Tahun 2009 dan PP No. 53 Tahun 2021. Kemudian, dalam aspek hukum Islam terdapat panduan mengenai transplantasi yang diatur berdasarkan Fatwa MUI No. 11 Tahun 2019. Kesimpulan dalam penelitian ini bahwa xenotransplantasi dalam hukum Islam berdasarkan fatwa MUI berpegang pada 3 kondisi penting yaitu Ad-Dharurah, Al-Hajah serta Tahsiniyat. Dalam artian xenotrasplantasi tidak diperbolehkan dalam kondisi pasien yang tidak mendesak sehingga disarankan untuk mencari pengobatan lain dengan pertimbangan keamanan, serta kehalalan. Adapun saran dalam penelitian ini adalah diharapkan tenaga kesehatan dapat bekerja lebih keras untuk menggunakan aspek syar’i dalam melakukan tindakan medis, serta diwujudkan dalam bentuk regulasi oleh pemerintah.
Upaya Administratif sebagai Instrumen Mewujudkan Penyelenggaraan Pemerintahan yang Baik Bagi Masyarakat
Authors: Safiuddin Sahrina , Muchtasar Rizal , Heryanti
Published: December 2022

Penulisan ini bertujuan untuk mengetahui bagaimana upaya administratif sebagai instrumen dalam mewujudkan penyelenggaraan pemerintahan yang baik bagi masyarakat dan faktor apa yang mempengaruhi penerapannya. Metode penelitian dan penulisan hukum yang digunakan adalah normatif (normative legal research) dengan bertumpu pada data sekunder dengan pendekatan perundang-undangan (statute approach). Analisis data dilakukan secara deskriptif yang memberikan gambaran utuh atas masalah yang diteliti. Hasil penelitian dan pembahasan menemukan bahwa (1) upaya administratif sebagai instrumen mewujudkan penyelenggaraan pemerintahan yang baik telah diatur dengan jelas secara substantif meliputi perubahan paradigma terkait administrasi pemerintahan dan telah runut secara prosedur yang ditempuh masyarakat jika terdampak hukum akibat tindakan pemerintahan baik akibat pembuatan keputusan maupun tindakan faktual. (2) Faktor-faktor yang mempengaruhi penerapannya dilihat berdasarkan struktur, substansi dan budaya hukum tampak terkendala pada struktur hukum yang belum memadai ditambah dengan budaya hukum masyarakat yang masih memiliki anggapan bahwa upaya administratif tidak akan berjalan optimal kecuali melalui gugatan ke pengadilan.
Peran Jaksa dalam Sistem Peradilan di Indonesia
Authors: Saputra Denny , Kurniawan  , Perdana Andi Surya , Murbawan Hendrik
Published: December 2022

Pada sistem peradilan Indonesia membagi beberapa ranah pengadilan di antaranya yaitu Pengadilan Negeri, Pengadilan Agama, Pengadilan Militer dan Pengadilan Tata Usah Negara. Dalam Pengadilan Negeri itu sendiri dapat membedakan antara pengadilan umum dan pengadilan khusus. Apabila ditinjau dari sisi peran, peran sendiri memiliki arti sebagai suatu rangkaian perilaku yang diharapkan dari seseorang atau sekelompok orang dengan berdasarkan posisi sosial, baik itu dengan cara formal maupun informal. Sehingga dapat ditarik kesimpulan bahwa peran merupakan tindakan yang dilakukan oleh seorang atau kelompok orang dalam suatu kejadian atau peristiwa. Berdasarkan Pasal 30 Undang-Undang Nomor 16 Tahun 2004 tentang Kejaksaan Republik Indonesia merupakan cerminan dari peran jaksa itu sendiri. Yang mana dalam pasal tersebut pada bidang pidana perdata maupun tata usaha negara kejaksaan dapat bertindak baik di dalam maupun di luar pengadilan untuk dan atas nama negara atau pemerintah. Jaksa dalam hal ini baik dalam bidang pidana, perdata maupun tata usaha negara memiliki fungsi untuk menegakkan keadilan, menjaga kewibawaan pemerintah, menyelamatkan kekayaan negara dan melindungi kepentingan masyarakat.
ANALYSIS OF TRAFFIC ROAD CAPACITY ON ROAD SECTION OF SEI LIAT PANGKALPINANG CITY BOUNDARY
Authors: Saraswati Adinda , Iskandar Isdaryanto ,   Atma Jaya Catholic University of Indonesia
Published: December 2022

The increasing number of vehicles in Bangka Belitung Province has caused several congestion points on several roads, one example in the Road Section of Sei Liat - Pangkalpinang City Boundary which is the main route connecting Pangkalpinang City with Sungailiat City. For the purpose of analyzing the existing capacity of the Sei Liat - Bts Road Section in Pangkal Pinang City, a traffic survey was conducted for seven days using CCTV as the data source. The average daily traffic volume value obtained on the Road Section of Sei Liat - Pangkalpinang City Boundarywas 11,156 vehicles/day or 902 pcu/hour. The value of Road Traffic Capacity obtained on the Road Section of Sei Liat - Pangkalpinang City Boundary was 2,977 pcu/hour with a degree of saturation of 0.3 which means that the Road Section of Sei Liat - Pangkalpinang City Boundary is included in the safe/unsaturated category and capable of serving vehicles that pass through this road every day.
iBiopsy® for Precision Medicine
Authors: Brag Johan , Auffret Michaël , Ramos Corinne , Liu Yan , Baudot Pierre
Published: December 2022

A high-throughput artificial intelligence-powered image-based phenotyping platform, iBiopsy® (Median Technologies, Valbonne, France), which aims to improve precision medicine, is discussed in the presented review. The article introduces novel concepts, including high-throughput, fully automated imaging biomarker extraction; unsupervised predictive learning; large-scale content- based image-based similarity search; the use of large-scale clinical data registries; and cloud-based big data analytics to the problems of disease subtyping and treatment planning. Unlike electronic health record-based approaches, which lack the detailed radiological, pathological, genomic, and molecular data necessary for accurate prediction, iBiopsy generates unique signatures as fingerprints of disease and tumour subtypes from target images. These signatures are then merged with any additional omics data and matched against a large-scale reference registry of deeply phenotyped patients. Initial applications targeted include hepatocellular carcinoma and other chronic liver diseases, such as nonalcoholic steatohepatitis. This new disruptive technology is expected to lead to the identification of appropriate therapies targeting specific molecular pathways involved in the detected phenotypes to bring personalised treatment to patients, taking into account individual biological variability, which is the principal aim of precision medicine.
Konversi Batubara Menjadi Syngas Menggunakan Metode Gasifikasi Dengan Variasi Air Fuel Ratio
Authors: Nurlatifah Ismi , Amyranti Mutia , Maftukhah Siti
Published: December 2022

Batubara merupakan salah satu komoditi sumber daya alam yang dihasilkan dari aktivitas pertambangan di indonesia dan merupakan bahan tambang strategis dalam penyediaan sumber energi. Untuk wilayah Banten batubara banyak ditemukan di daerah Banten Selatan tepatnya di daerah Bayah. Gasifikasi merupakan solusi untuk pemanfaatan batubara. Gasifikasi batubara adalah proses konversi batubara berwujud padat menjadi campuran gas. Reaksi utama yang terjadi adalah reaksi water gas, boundouard dan water gas-shift. Penelitian ini bertujuan untuk mengetahui pengaruh Air Fuel Ratio (AFR) gasifikasi pada proses gasifikasi batubara Alam Bayah Banten yang menghasilkan gas sintesis dengan Rasio H2/CO ≈ 2. Parameter yang diukur adalah komposisi gas H2 dan CO dengan menggunakan Gas Chromatography. Proses gasifikasi dilakukan dengan reaktor fixed bed tipe updraft menggunakan medium steam pada ukuran batubara 14 mesh sebanyak 300 gram dengan variasi AFR 1,5, 2 dan 2,5 pada temperatur 800oC. Energi aktivasi reaksi gasifikasi dapat diturunkan dengan menggunakan katalis Ca(OH)2 sebanyak 3% dari massa batubara. Dari hasil penelitian diperoleh komposisi gas syngas rasio H2/CO terbaik pada nilai AFR 1,5 temperatur 800oC menggunakan katalis Ca(OH)2 yaitu 1,98 dengan komposisi gas H2 33,8% dan gas CO 17,1%.
Analysis of Changes in Saliva Composition in Adult Patients
Authors:   The Korean Society of Oral Health Science, Kwon Hong-Min , Choi Won-Joo , Lee Sun-Mi
Published: December 2022

Objectives: This study analyzes the saliva of adult patients using the Sill-Has ST-4910 salivary measurement system and evaluates the possibility of future application of the salivary measurement system in the clinic. Methods: First saliva measurement was performed on 38 patients aged between 20 and 65 who visited the dental clinic, followed by expert dental plaque management, followed by secondary saliva measurement 4 weeks later. Results: In all items, the value of the second survey was lower than the value of the first survey, indicating a significant difference. Conclusions: The proposed salivary measurement system can be expected to gain widespread usage in dental clinics due to its advantages.
Uluslararası Hukuk Kaynakları Çerçevesinde İş Hukukunda Cinsiyet Ayrımcılığı
Authors: KONUK Gülşah
Published: December 2022

Toplumsal cinsiyet rolleri sebebiyle, çalışma hayatında cinsiyet temelli ayrımcılık, sıklıkla karşılaşılan bir durumdur. Özellikle aile sorumlulukları ve güçsüz kabul edilmeleri sebebiyle kadınlar, cinsiyete dayalı ayrımcılığa daha çok maruz kalıyor olsalar da toplumda kadının yapacağı iş olarak kabul edilen bazı meslekler bakımından erkeklerin de cinsiyet ayrımcılığı ile karşı karşıya kaldıkları durumlar olabilmektedir. Bununla birlikte son zamanlarda kendinden söz ettirmeye başlayan cinsel yönelim sebebiyle ayrımcılık da çalışma hayatında cinsiyete dayalı ayrımcılığın unsurlarından biri haline gelmiştir. Çalışma hakkı ve kendini geliştirme hakkı çerçevesinde bireylerin cinsiyete dayalı ayrımcılığa maruz kalmaları, aynı zamanda insan hakları ihlali niteliğindedir. Bu tür ayrımcı muameleleri engellemek üzere pek çok uluslararası düzenlemede konuya ilişkin hükümler yer almaktadır. Bu düzenlemeler tek başına cinsiyet ayrımcılığını engellemeye muktedir olamamakta, bu hükümlerin yargı kararlarıyla desteklenmesi ve toplumsal cinsiyet rollerinin yol açtığı kalıp yargıların önüne geçilmesi gerekmektedir. Çalışmamızda, ilgili uluslararası düzenlemeler ve yargı kararları ile birlikte, Türk iş hukukundaki düzenlemeler ve yargı kararları çerçevesinde inceleme yapılmıştır.
A Study on the Similar Structure of Baratanatiyam and Hatha Yoga Based on The Shiva Mythology
Authors:   The Korean Society of Culture and Convergence, Kim Youngsuk
Published: December 2022

This study analyzed similar structure between the traditional dance of Baratanatiyam which has deep Indian history and Hatha yoga which is centered on physical training, based on Shiva mythology. For conducting the research, we collected various papers and journals related to Shiva mythology, Indian dance, Hatha yoga, and other scientific articles on Indian traditional dance to enhance understanding of Indian traditional culture. Through this, the background composition and characteristics of Indian dance and Hatha yoga derived by Shiva mythology were identified and the gestures of the shiva god were used to symbolize the meanings contained in the gestures. First, it has a symbolic similarity that coincides with the ultimate goal of reaching the state of liberation. Second, the characteristics of Nritta, Nritya, and Natya of Baritanatiyam have structural similarities that work similarly to the structure of Hatha Yoga. Third, symmetrical and repetitive motions and elaborate and standardized motions act in the same pattern. As a result, this study focuses on the understanding of contact between Indian dance and Hatha yoga, which have been separated into different areas and develops the new language of yoga that has become popular in Korea and embraces it within dance studies to promote diversity in dance studies.
Analysis on Foreign Drug Offenders Covered in Media
Authors:   The Korean Society of Culture and Convergence, Shin Jaehun , Kim Sangwoon
Published: December 2022

The purpose of this paper is to examine the cases of rapidly increasing foreign drug offenders, identify their characteristics, and suggest the measures against the foreigner drug issues. This paper analyzed the recent foreign drug crimes covered in the media by referring to the preceding research, statistics on foreigner drug, and the crime of narcotics white paper. Among the recent increase in the crimes committed by foreigners, the foreign drug offenders are rising. These criminals are different from the existing drug-related crime in Korea. Instead, they commit new forms of drug-related crimes, such as production and distribution of the illicit drugs. This resulted in harming the title as “Drug-Free Country” and qualitatively changing the ecosystem in Korea. As a result, the foreign drug-related crimes showed characteristics of online SNS-based distribution, drug smuggling using international mail, distribution of new type of drug, popularization of drug offender, and increase in drug distribution at farming areas and manufacturing areas.
Analysis of Idol Marketing Success Factors through Metaverse Platform
Authors:   The Korean Society of Culture and Convergence, Jo Hakyung , Jeon Yoonhan
Published: December 2022

This study analyzed the success factors of idol-marketing through the metaverse platform, which has become a new marketing tool in the era of untact(Non-Contact) accelerated by COVID-19. Research was conducted based on the analysis of idol-marketing cases by using the metaverse platform and the analysis of acceptance recognition through literature research. For more in-depth research, the target of the study were limited to the marketing using Zepeto by the K-Pop girl group 'Black Pink'. Result of the analysis was confirmed by the five factors which includes smooth communication, direct experience, overcoming spatial limitations, targeting the MZ generation and oversea users, and lastly generate revenue was served as success factors.
Analysis of College Student’s Perception of Liberal Arts Classes and Demands for Improvement of Liberal Arts Curriculum
Authors:   The Korean Society of Culture and Convergence, Kim Jongsuk
Published: December 2022

The purpose of this study is to draw improvement plans by identifying the perceptions of good liberal arts classes of college students and the demand for organization and operation of liberal arts curriculum for those who have taken liberal arts classes. The FGI study was conducted as a research method, and 73 university students (30 in 2020, 43 in 2021) participated. Data collection was conducted for 1 hour 7 times in November 2020 and 12 times in November 2021. FGI data were transcribed and the content was analyzed and classified. The main research results are as follows. First, students perceived interactive classes, classes without grades, classes with easy explanations, classes with updated content, and classes that broaden their horizons as good liberal arts classes. Second, in relation to the organization and operation of the liberal arts curriculum, it was requested to reduce the number of credits required to complete the liberal arts, increase the number of classes, and improve the operation of language and expression/foreign language/liberal education fields. Third, based on the results of the analysis, measures were sought to improve the quality of the liberal arts curriculum.
A Study on the Current Status of Character Education Curriculum in College’s Liberal Arts Education
Authors:   The Korean Society of Culture and Convergence, Lee Yeonjoo , Jeon Jonghee
Published: December 2022

The purpose of this study is to check the current status of the subjects of character education in college’s liberal arts education and to explore future educational directions. To this end, in this study, from June to November 2020, through literature research and survey development and consultation related to character education, questions were confirmed and surveyed, and results were analyzed and discussed. Considering that it is not easy to cooperate with each university due to COVID-19, related information was investigated online such as universities' websites. The subjects of this study became a total of 115 universities. As a result of the study, there were many cases where the domain called 'character' was not organized separately, and the degree of non-organization in the sub-category of character education was also varied. The percentage of subjects opened was 'emotional/aesthetic experience', 'employment/start-up', and 'physical experience' in the order. As for the required subjects, ‘college life guidance for freshmen' and 'college teaching' were high. According to the results of the analysis of 'character education' subjects, the subjects in the physical and emotional experience domain showed clear and differentiated characteristics. It was confirmed that the history and tradition of character education are in touch with the present. Through this study, it will be possible to examine the purpose and operational status of character education in college’s liberal arts education and to explore the future educational directions.
A Study on the Phenomenon of Music Promotion using TikTok
Authors:   The Korean Society of Culture and Convergence, Chen Yu , Kim hyun tai
Published: December 2022

TikTok, developed in 2017 in China, has sparked a worldwide craze with its short video, and among TikTok's video content, “Music + short video” has developed into the most effective promotional method in new popular music. However, as there are two sides to everything, the popularity of TikTok brings opportunities to the music industry, but also brings problems. This paper explored the new mode of music promotion led by TikTok and the characteristics of music propagation in TikTok. It also considered and analyzed the impact of TikTok's promotion mode on music creation, and the possible problems caused by the current copyright cooperation mode between TikTok and the music industry.
Analysis on Sales Products and Consumer Preference Design for Small Wedding Dresses Planning
Authors:   The Korean Society of Culture and Convergence, Han Eunkyoung , Lim Ji Young
Published: December 2022

The purpose of this thesis is to consider the wedding dress designs preferred by the Generation MZ who are the core consumers of wedding market, in order to suggest wedding dresses suitable for the changed small wedding culture. For this, this study analyzed the designs of small wedding dresses currently sold in shopping malls, and then conducted a survey on the preferred designs of small wedding dresses targeting the Generation MZ, especially the unmarried women in their 20s-30s. The results showed the necessity to have the designs with practical image besides the dresses with elegant or classical image mostly shown in the existing wedding dresses, to expand the form from one-piece type with full-length & maxi length to various items of two-piece type such as jacket & skirt or jacket & pants, and to expand the color from white color to various colors like light gray, red, or navy color. It would be necessary to develop the design of wedding dress in the form of everyday wear. The results of this study could be working as the criteria of new wedding dresses for the Generation MZ who pursue such individual and practical wedding.
A Phenomenological Study on the Experience of Career Choice of Out-of-School Adolescents Who Do Not belong to Youth Institutions
Authors:   The Korean Society of Culture and Convergence, Lee seon hwa , Lee Seonyoung
Published: December 2022

This study aims to investigate the career choice experience of out-of-school adolescents who are not affiliated with the institution.,The study was conducted for out-of-school youths living in K city, and four youths who were not affiliated with youth-related organizations were selected.,In-depth interviews were conducted based on changes before and after school interruption and career choice experience., Giorgi's phenomenological method was analyzed according to the procedure, and as a result, four essential themes and 12 central themes were derived, saying that my life, which I have to take responsibility for myself, can start and do, and that two years of empty time is nothing.,The study on the deep story about the experience before and after the school interruption and the experience of career choice in the out-of-school environment is meaningful in that it gives more effective support and help to out-of-school youths by sharing the experience of realistic career that out-of-school youths should face and it is not enough data about youths who are not affiliated with youth-related organizations.
A Study on the Gamification Elements Affecting the User Experience of Mobile Services of Securities Companies: Focusing on the MZ Generation
Authors:   The Korean Society of Culture and Convergence, Won Changsun , Sul Sanghun
Published: December 2022

The purpose of this study is to present gamification elements that affect user experience in building securities company mobile service for MZ generation, which is emerging as the next-generation major customer of securities companies. To this end, we conducted a workshop that applied the service design methodology, the double diamond process. First, MZ generation characteristic keyword, Pain point, Persona were derived, and based on this, service concept and service content were derived. Next, we created a prototype by applying gamification elements to service content. Finally, the MZ generation participated in the prototype verification, and After the in-depth interview, qualitative analysis and quantitative analysis were conducted. Through this analysis, the main gamification elements affecting the user experience of MZ generation are the fun elements of social interaction, reward, and Altruism, and the game mechanism elements of social engagement loop, Virtual goods, and Gifts and charity.
Analysis of Music Intervention Studies on the Elderly at Residential Care Facilities in Korea
Authors:   The Korean Society of Culture and Convergence, Kim Jueun , Park Hye Young
Published: December 2022

The purpose of this study was to review trends and characteristics of the researches on the elderly in care facilities rapidly increased due to societal aging. For this, 13 researches published in KCI journals that met the analysis criteria were selected and analyzed according to general characteristics, variables, results, and rationale evaluation as well as reporting guidelines for music interventions. As a result, regarding intervention goals, psychological and emotional domains accounted for the largest proportion and this seems to be associated with the trait of the elderly in care facilities more vulnerable in that domains than the general elderly due to residing in a closed space and experiencing changes in their living. Recent researches have clearly outlined the connection between music interventions and their goals to support rationale reflecting a continuous development in the area. The analysis based on the guidelines revealed that delivery unit and schedules of interventions were relatively well reported, however, therapist, intervention integrity, and setting were not sufficiently described. It is meaningful that this study suggests directions for strengthening the expertise and effectiveness of further research by in-depth analysing music intervention researches focusing on the elderly in care facilities.
A Study on the Methodology of Strengthening Competencies of Vietnamese Students Studying in Korea
Authors:   The Korean Society of Culture and Convergence, Seo Jeong Mok
Published: December 2022

The purpose of this study is to present convergence majors and programs, and a systematic methodology for strengthening the competency of Vietnamese students studying in Korea. By applying this methodology, if Vietnamese students succeed in finding jobs or starting businesses in Korea or in Vietnam, a virtuous cycle which creates demands for new Vietnamese students can be established. The specific methods are as follows; first, academic guidance and career coaching by Vietnamese, second, the education of languages for specific purposes, third, the major of Vietnamese interpretation and translation, fourth, reverse study abroad system in Vietnam and credit exchange system with Vietnamese universities based on distance learning system, fifth, convergence majors with Vietnamese characteristics such as Southeast Asian studies and multinational tax accounting major, sixth, joint operation of online courses between Korean and foreign universities and a credit linkage system between the universities in both countries.
A Teaching Case Study Using Facilitation in the Subject of Thinking and Expression
Authors:   The Korean Society of Culture and Convergence, Yu Yukrye
Published: December 2022

This paper analyzes the creative integration competency and problem-solving abilities of students in C University. With facilitation teaching method, they learned the topics of . In classes, they discussed learning topics one another and a representative of each group announced the contents to other students. After filling their ideas in a questionnaire, students represented their ideas, completing the topic of what they learned. In this process, they showed a variety of ideas and had a creative discussion. Moreover, they improved smooth communication by respecting other members’ opinions. Therefore the class of facilitation enabled students to present their ideas and greatly contribute to enhance students’ creation-conversion competency and problem-solving abilities, with students structurely perceiving the learning topics.
Strategi manajemen produksi untuk memaksimalkan profitabilitas pada provider perspektif islam
Authors: Syukur Musthafa , Fitri Yoviana
Published: December 2022

Penelitian ini bertujuan untuk mengungkap strategi manajemen produksi dalam menghasilkn profitabilitas pada persuasahaan provider  sehingga dapat mengahsilkan kemaksimlakan dalam laba perusahaan. Metode yang di gunakan adalah kualitatif dengan pendekatan studi literatur. Hasil dari penelitian ini dikemukan bahwa starategi yang dilakukan oleh provider dengan mengatasnamakan embel embel islam terbukti efektif untuk menarik custumer dalam membeli yang di tawarkan oleh provider, sehingga provider menghasilkan laba profit yang melebiha standart yang ditentukan oleh perusahaan.
Apakah Belanja Pemerintah Pusat Bersinergi dengan Belanja Daerah?
Authors: Astuti Resti , Khoirunurrofik Khoirunurrofik
Published: December 2022

Indonesia telah menerapkan desentralisasi selama dua dekade. Transfer ke Daerah dan Dana Desa (TKDD) sebagai instrument desentralisasi mengalami peningkatan yang sangat tinggi sehingga mendorong peningkatan belanja daerah. Beberapa penelitian telah mengidentifikasi faktor-faktor yang mempengaruhi belanja daerah di Indonesia, antara lain PAD, dana perimbangan dan populasi. Pada penelitian ini, penulis tidak hanya ingin menguji pengaruh dari faktor-faktor tersebut namun juga tertarik untuk menguji hubungan antara belanja pemerintah pusat di daerah dan belanja daerah untuk melihat apakah belanja pemerintah pusat di daerah dapat menstimulus belaja daerah. Dengan menggunakan data panel kabupaten/kota di Indonesia untuk periode 2010-2019 dan metode fixed effect model (FEM), hasil penelitian menunjukkan bahwa belanja pemerintah pusat di daerah berkorelasi positif dengan belanja daerah di Indonesia. Artinya, belanja pemerintah pusat di daerah dapat menjadi stimulus dalam meningkatkan belanja daerah.
The progress in titanium alloys used as biomedical implants: From the view of reactive oxygen species
Authors: Yang Jun , Liu Chang , Sun Hui , Liu Ying , Liu Zhaogang , Zhang Dan , Zhao Gang , Wang Qiang , Yang Donghong
Published: December 2022

Titanium and Titanium alloys are widely used as biomedical implants in oral and maxillofacial surgery, due to superior mechanical properties and biocompatibility. In specific clinical populations such as the elderly, diabetics and patients with metabolic diseases, the failure rate of medical metal implants is increased significantly, putting them at increased risk of revision surgery. Many studies show that the content of reactive oxygen species (ROS) in the microenvironment of bone tissue surrounding implant materials is increased in patients undergoing revision surgery. In addition, the size and shape of materials, the morphology, wettability, mechanical properties, and other properties play significant roles in the production of ROS. The accumulated ROS break the original balance of oxidation and anti-oxidation, resulting in host oxidative stress. It may accelerate implant degradation mainly by activating inflammatory cells. Peri-implantitis usually leads to a loss of bone mass around the implant, which tends to affect the long-term stability and longevity of implant. Therefore, a great deal of research is urgently needed to focus on developing antibacterial technologies. The addition of active elements to biomedical titanium and titanium alloys greatly reduce the risk of postoperative infection in patients. Besides, innovative technologies are developing new biomaterials surfaces conferring anti-infective properties that rely on the production of ROS. It can be considered that ROS may act as a messenger substance for the communication between the host and the implanted material, which run through the entire wound repair process and play a role that cannot be ignored. It is necessary to understand the interaction between oxidative stress and materials, the effects of oxidative stress products on osseointegration and implant life as well as ROS-induced bactericidal activity. This helps to facilitate the development of a new generation of well-biocompatible implant materials with ROS responsiveness, and ultimately prolong the lifespan of implants.
Challenges confronting construction information management
Authors: Adekunle Peter , Aigabvboa Clinton , Thwala Wellington , Akinradewo Opeoluwa , Oke Ayodeji
Published: December 2022

This paper aims to present the results of an investigation of the prevailing challenges in construction information management. The study implemented a quantitative survey methodology, using a questionnaire to gather data from architects, civil engineers, quantity surveyors, mechanical and electrical engineers, construction managers, and project managers. Data analysis was conducted using the SPSS software package: applicable measures of dispersal were computed and inferential statistical tests performed. The study revealed that information management is a significant aspect of construction procedures and that a well-structured information system must be in place to achieve success in the construction domain. Additionally, the researchers discovered that construction information management could be affected by both internal and external factors within an organization. Further findings revealed that the major challenges in construction information management are long-term reliance on legacy systems, a lack of technological equipment, leadership development, poor financial investment in infrastructure for data management, and the implementation of appropriate policies by management. The primary contribution of this study lies in its appraisal of the difficulties facing construction information management and its identification of the relevant challenges, which can help in the proposal of solutions to improve methods of managing construction information, in turn producing improved performance and more efficient delivery of services on the part of professionals within the construction industry.
AUF-1 knockdown in mice undermines gut microbial butyrate-driven hypocholesterolemia through AUF-1–Dicer-1–mir-122 hierarchy
Authors: Das Oishika , Kundu Jayanta , Ghosh Atanu , Gautam Anupam , Ghosh Souradeepa , Chakraborty Mainak , Masid Aaheli , Gauri Samiran Sona , Mitra Debmalya , Dutta Moumita , Mukherjee Budhaditya , Sinha Surajit , Bhaumik Moumita
Published: December 2022

Introduction and objective

Cholesterol homeostasis is a culmination of cellular synthesis, efflux, and catabolism to important physiological entities where short chain fatty acid, butyrate embodied as a key player. This discourse probes the mechanistic molecular details of butyrate action in maintaining host-cholesterol balance.

Methods

Hepatic mir-122 being the most indispensable regulator of cholesterol metabolic enzymes, we studied upstream players of mir-122 biogenesis in the presence and absence of butyrate in Huh7 cells and mice model. We synthesized unique self-transfecting GMO (guanidinium-morpholino-oligo) linked PMO (Phosphorodiamidate-Morpholino Oligo)-based antisense cell-penetrating reagent to selectively knock down the key player in butyrate mediated cholesterol regulation.

Results

We showed that butyrate treatment caused upregulation of RNA-binding protein, AUF1 resulting in RNase-III nuclease, Dicer1 instability, and significant diminution of mir-122. We proved the importance of AUF1 and sequential downstream players in AUF1-knock-down mice. Injection of GMO-PMO of AUF1 in mouse caused near absence of AUF1 coupled with increased Dicer1 and mir-122, and reduced serum cholesterol regardless of butyrate treatment indicating that butyrate acts through AUF1.

Conclusion

The roster of intracellular players was as follows: AUF1-Dicer1-mir-122 for triggering butyrate driven hypocholesterolemia. To our knowledge this is the first report linking AUF-1 with cholesterol biogenesis.
Comparison of high throughput RNA sequences between Babesia bigemina and Babesia bovis revealed consistent differential gene expression that is required for the Babesia life cycle in the vertebrate and invertebrate hosts
Authors: Capelli-Peixoto Janaina , Saelao Perot , Johnson Wendell C. , Kappmeyer Lowell , Reif Kathryn E. , Masterson Hayley E. , Taus Naomi S. , Suarez Carlos E. , Brayton Kelly A. , Ueti Massaro W.
Published: December 2022

Bovine babesiosis caused by Babesia bigemina and Babesia bovis is an economically important disease that affects cattle worldwide. Both B. bigemina and B. bovis are transovarially transmitted by Rhipicephalus ticks. However, little is known regarding parasite gene expression during infection of the tick vector or mammalian host, which has limited the development of effective control strategies to alleviate the losses to the cattle industry. To understand Babesia gene regulation during tick and mammalian host infection, we performed high throughput RNA-sequencing using samples collected from calves and Rhipicephalus microplus ticks infected with B. bigemina. We evaluated gene expression between B. bigemina blood-stages and kinetes and compared them with previous B. bovis RNA-seq data. The results revealed similar patterns of gene regulation between these two tick-borne transovarially transmitted Babesia parasites. Like B. bovis, the transcription of several B. bigemina genes in kinetes exceeded a 1,000-fold change while a few of these genes had a >20,000-fold increase. To identify genes that may have important roles in B. bigemina and B. bovis transovarial transmission, we searched for genes upregulated in B. bigemina kinetes in the genomic datasets of B. bovis and non-transovarially transmitted parasites, Theileria spp. and Babesia microti. Using this approach, we identify genes that may be potential markers for transovarial transmission by B. bigemina and B. bovis. The findings presented herein demonstrate common Babesia genes linked to infection of the vector or mammalian host and may contribute to elucidating strategies used by the parasite to complete their life cycle.