bluuebunny/crossref_metadata_2025 huggingface dataset:
Ancient schwannoma (Neurilemmoma) of the tongue: A rare case report
Authors: Deepthi TR  , Sasikumar Prem , Adarsh VJ  , Vani MH  , Vijayan Anu , Maheesan Kavya
Published: December 2022

Schwannoma or neurilemmoma is an uncommon, benign peripheral nerve tumor derived from Schwann cells. It is usually a slow growing, asymptomatic, well encapsulated tumor that arises in association with a nerve trunk.Here we present a rare case of Ancient Schwannoma in a 20 year old male. The patient presented with a small, slow growing asymptomatic mass on the dorsal surface of the tongue, present since past 1year. Lesion was completely excised. Diagnosis was confirmed by histopathology and immunohistochemistry.
Trends in dengue virus infection with seasonal variation at a tertiary care centre, Mangaluru: A retrospective study
Authors: Sharma Prajna , K Pavithra , Shettigar Sanchita
Published: December 2022

: Dengue is currently the second most prevalent vector borne disease in the world. Dengue fever and its more serious forms, dengue hemorrhagic fever and dengue shock syndrome are becoming important public health problems. Since there is no immunoprophylaxis or specific antiviral therapy available, clinico-microbiological diagnosis plays a vital role in patient management and implementation of control measures.

: To identify dengue seropositive patients by NS1 antigen and anti-dengue IgM antibody detection by ELISA and correlate the changes in epidemiology.

A retrospective study was performed for a period of 5 years from January 2017 to December 2021 in A.J Institute of Medical Sciences & Research Centre, Mangaluru. 1871 seropositive cases of all age groups admitted in the medical wards were included. Rapid immunochromatography test and ELISA was performed to detect NS1 antigen and IgM antibodies. Platelet count and total leucocyte count were also analysed.

: Out of 14656, 1871 samples (12.75%) were positive for dengue. Higher rate of cases were in males and the age group of 21 to 30 years were chiefly affected. 1158(61.89%) were positive for NS1 antigen and total positive cases for IgM antibody was 530(28.32%). About 183 (9.79%) cases were positive for both NS1 antigen and IgM antibody. An increase in the prevalence of dengue was recorded during the month of June to October.

The present study indicates a decline in dengue infection from 2020 which may be attributable to preventive and control measures provided by the health care workers besides having increased awareness among people. The decline may also may be due to the outbreak of SARS –Cov-2 in December 2019, which led to under diagnosis of dengue cases.
Bacterial urinary tract infection in diabetes patients and evaluation for multidrug resistant organisms
Authors: Narayanaswamy Girish , S.P Reenu , Kushwaha Ramesh Kumar
Published: December 2022

Bladder infection exists as frequently occurring infectious disease in diabetic mellitus of all distinct age groups. Acute cystitis is recognised as higher frequency in person with diabetes. Urinary Tract infection is most familiar and widespread infection in world-wide. The frequency of urinary tract infection is at peak in patients with diabetic mellitus. Diabetic mellitus (DM) is a group of metabolic impairment characterised by hyperglycaemia resulting from defects in insulin secretion, insulin action or both. It’s a common disease that affects health in many ways and relevant problems one of the leading illness world-wide. Urinary tract infection medical aid experimental is less execution of urine culture and sensitivity. In the present study designed to find out occurrence of bacterial urinary tract infection, Multidrug resistant organisms, health risk and antimicrobial drug medication for UTI’s.

To hypothesize the spectrum of uropathogens and the profile of antibiotic resistance pattern in both diabetic and non-diabetic patient with asymptomatic urinary tract infection.

The research study was performed for the duration of 6 Months (April-September 2022) in Vydehi Institute of medical science and research centre (VIMS & RC) Whitefield Bangalore. Diabeticas well as non-diabetic patientsabove 18 years of age, from OPD and also admitted in General medicine department of VIMS & RC was considered. A total of 247 diabetic and non-diabetic urine samples from outpatients and inpatients was collected and processed in the microbiology laboratory. In accordance to principle of Clinical and Laboratory Standards Institute, the urine samples was collected and analysed. VITEK 2 Automated system analyser was used to determine Antimicrobial Sensitivity.

Bacterial Multidrug Resistant Organism isolates in diabetes mellitus with bacteriuria is 48 (53%). Bacterial isolates in non-diabetic mellitus with bacteriuria is 29 (17%). and is frequently isolated. Gram-negative bacteria are highly resistant to multiple drugs like, Amikacin, Nitrofurantoin, Ceftriaxone, Clavulanic acid, Cefpirome, etc moreover increasingly resistant accessible antibiotics.

and was the most familiar isolated microorganisms.
Unusual non-albicans candida yeast in South India: Incidence in cancer patients and antifungal susceptibility towards first-line drugs
Authors: K Umamaheswari , Ranganathan Gnanasekar , Chellappa Arun Kumar
Published: December 2022

Unusual Ascomycetes yeasts are frequently reported in obstinate infections among the cancer population. Emergence of resistance among the non-albicans yeasts towards promising first-line azoles queries over treatment options. The present study probes on the recent trends in incidence of and emerging non- albicans yeasts in cancer patients and to determine the species-wise antifungal susceptibility towards first-line Triazoles and Echinocandin.

A total of 53 isolates recovered from the clinical specimens collected from 87 cancer patients were presumptively identified on CHROMagar and speciated by sequencing internal transcribed spacer (ITS) target. The species-wise antifungal susceptibility were determined for the first-line triazoles (Fluconazole, Voriconazole, Posaconazole) and Echinocandin (Anidulafungin) following CLSI guidelines.

The proportion of Candida isolates were predominantly non-albicans Candida (NAC) species (85%) and (15%). All isolates were speciated using ITS sequencing and the spectrum of NAC species isolated were dominated with (17) followed by (9), (5), C. tropicalis (4), (3), (3), (2) and one isolate of each and The unusual NAC species showed varied resistance profile towards first-line azoles and were susceptible to Anidulafungin.

The changing spectrum, high prevalence and pattern of low level azoles susceptibility among unusual NAC species recovered from the cancer population are alarming.
Eumycetoma infection of the hand: A case report
Authors: Tomar Jyoti , Goyal Neelima , Jangid Ketki
Published: December 2022

Mycetoma is a chronic granulomatous infection of cutaneous and subcutaneous tissues caused by filamentous bacteria (actinomycetoma) or fungi (eumycetoma). The most common site of infection is the foot, followed by the hand, but sometimes other body parts may also be infected. The patients present with a painless hard and swelling subcutaneous mass, multiple sinuses, and the pathognomonic discharge of grains. A 42-year-old male patient, presented pain and swelling in his right hand and also complained of swelling in his right forearm. The swelling later involved his whole right hand and wrist joint. Physical examination revealed multiple discharging sinuses with serosanguineous exudates and black grains. Swelling and local erythema were present, lymph nodes were not palpable. The patient complained of constant mild pain which is relieved by pain medications. The serohematic discharge was witnessed with conglomerates of small and firm blackish pellets, evoking eumycetomaSaline dressing was applied overnight and next morning grains were directly collected from sinuses. Tissue and black grain samples were analyzed for bacterial and mycological evaluation. Direct microscopy was performed using Gram stain showed thicker hyphae of eumycetoma. Modified ZN stain showed no acid fast bacilli. LPCB was helpful in confirming thicker hyphae of eumycetoma. Here, on clinical diagnosis (classical triad that is, painless soft tissue swelling, draining sinuses and extrusion of grains) with microbiological investigation, we concluded it a case of “Eumycetoma”.
Imported malaria with chikungunya co-infection: A case report
Authors: Das Anupam , Sen Manodeep , Pandey Pranshu , Rautela Apurva , Jafar Haniya , Singh Vikramjeet , Garg Jaya , Agarwal Jyotsna
Published: December 2022

Malaria is a parasitic disease caused by and is associated with acute febrile episodes. The disease burden is highest in Southeast Asia. Various measures are being taken to curb the disease in different countries. Even after the introduction of various programmes there has been reports of imported malaria which has been transported from highly endemic countries to less endemic or countries not having cases of Malaria. Not only this, various other viral disease come in as coinfection with malaria which makes the situation even worse. Here we describe one such case of malaria imported from traveller from Nigeria to India who also developed coinfection with Chikungunya.
A importância do geoprocessamento na opinião de pessoas apresentadas a um software SIG livre, através de minicursos
Authors: Souza Júnior Teobaldo Gabriel de , Lima Mirelle Tainá Vieira , Palácio Orjana Dias , Oliveira Carlos Wagner
Published: December 2022

O projeto objetivou prover a diversos profissionais e estudantes, minicursos de introdução ao geoprocessamento utilizando o software QGIS. Executadas entre janeiro e dezembro de 2019, pelo grupo de extensão denominado Laboratório de Estatística, Modelagem e Geoprocessamento (LEMGE) da Universidade Federal do Cariri (UFCA), as referidas formações contemplaram 108 pessoas e visaram apresentá-las a uma ferramenta tecnológica gratuita, bastante utilizada na gestão de informações georreferenciadas. Concluiu-se que, na opinião dos participantes, as ações foram válidas podendo auxiliar tanto na sua prática cotidiana quanto na construção de novos conhecimentos, o que endossa a necessidade da constante aproximação de diversos nichos de trabalho ao estado da arte das geotecnologias contemporaneamente difundidas.
PRÁTICAS DE EXTENSÃO NO IFRS CAMPUS BENTO GONÇALVES: CURSO DE LÍNGUA PORTUGUESA PARA IMIGRANTES E REFUGIADOS E VI SEMANA DE LÍNGUA E LITERATURA
Authors: Nunes Alicia Kuhn , Merlo Ana Júlia Tesser , Zimer Bárbara , Gebing Samuel Ânderson , Balzan Carina Fior Postingher , Eckert Kleber
Published: December 2022

Este relato de experiência busca discutir a curricularização da extensão no ensino superior ao apresentar as atividades realizadas no componente curricular Estágio Supervisionado - Projetos de Extensão, no curso de Licenciatura em Letras - Língua Portuguesa do IFRS - Campus Bento Gonçalves. Um dos compromissos das instituições de ensino superior é desenvolver ações de extensão que atendam às necessidades da sociedade, promovendo, assim, a democratização do conhecimento. Aborda-se, no texto, a prática realizada pelos licenciandos dentro de dois projetos de extensão: o Curso de Língua Portuguesa para imigrantes e refugiados e a VI Semana de Língua e Literatura. A partir desse estágio, percebe-se a importância da imersão dos futuros docentes em ações de extensão, cujos benefícios se fazem sentir tanto para a formação acadêmica dos licenciandos quanto para os públicos atendidos pelos projetos.
CONHECENDO A INFORMÁTICA POR INTERMÉDIO DO PROGRAMA MULHERES MIL: EXPERIÊNCIA NO IFRN/CEARÁ-MIRIM
Authors: De Oliveira Idelmárcia Dantas , Da Silva Sara Barbosa
Published: December 2022

Este artigo pretende descrever a experiência vivenciada durante a realização da primeira turma do Programa Mulheres Mil no Campus Ceará-Mirim do Instituto Federal de Educação, Ciência e Tecnologia do Rio Grande do Norte. O programa foi implementado por meio de Projeto de Extensão com vistas a oferta de Curso de Formação Inicial e Continuada em Operador de Computador, cuja execução ocorreu no ano de 2019. Das 30(trinta) mulheres que iniciaram o curso, 18(dezoito) concluíram. As principais dificuldades enfrentadas pela coordenação de curso foram o acesso aos laboratórios de informática em condições adequadas e a indisponibilidade de professores do Campus para a condução das disciplinas técnicas do curso. O apoio de alunos voluntários foi considerado imprescindível para o andamento do curso, assim como dos servidores do quadro técnico administrativo. Por fim, as alunas participantes avaliaram a experiência como positiva e externaram interesse em continuar os estudos, após a finalização do curso e, ainda, relataram que utilizarão os conhecimentos adquiridos em seus negócios.
Expediente
Authors: Abiahy Ana Carolina De Araújo
Published: December 2022

v. 10, n. 21 (2022): Revista Práxis: saberes da extensão
CONSCIENTIZAÇÃO PARA A SUSTENTABILIDADE AMBIENTAL CONSIDERANDO O CONFORTO AMBIENTAL E O USO DE TECNOLOGIAS BIM EM ESCOLA PÚBLICA (CAJAZEIRAS – PB)
Authors: Dias David Dos Santos , Junior Francisco Edmilson dos Passos , Oliveira Daniel Cosmo , Maciel José Thiago Silva , Oliveira José Lucas Pessoa , Freitas Lucas Tavares de , Sarmento Thauan Ribeiro
Published: December 2022

As escolas são ambientes de extrema importância na formação moral e intelectual do ser humano. Portanto, é indispensável que as salas de aula apresentem o mínimo de conforto necessário para um bom aprendizado. Dessa forma, o presente trabalho de extensão teve o intuito de retratar as condições de bem-estar de alunos e professores das escolas públicas de Cajazeiras-PB e para isso foram analisados três parâmetros: térmico, acústico e lumínico. O térmico é levado em conta devido ao clima semiárido em que se localiza a região do município, sendo responsável por temperaturas elevadas em boa parte do ano; o acústico devido ao fato de isso interferir na comunicação entre aluno e professor; e no contexto de iluminação do ambiente foi avaliado condições lumínicas, em função de que os alunos necessitam de uma boa percepção visual do que está escrito no quadro, bem como para a realização de anotações. Para essa análise, foram coletados dados de uma escola da rede pública através de medições utilizando equipamentos apropriados e posteriormente os resultados foram comparados com os parâmetros estabelecidos nas Normas Brasileiras (NBRs). Além disso, foi realizado algumas atividades, dinâmicas e debates com os gestores e alunos da escola, a fim de instigar a interação do ambiente escolar básico com a universidade, e levar informações sobre a importância de se avaliar o conforto ambiental dos alunos durante as aulas.
NEGÓCIO LOCAL - PLATAFORMA ONLINE PARA DIVULGAÇÃO DE MICRO E PEQUENOS EMPREENDIMENTOS
Authors: Moura Costa Antonio Alexandre
Published: December 2022

A pandemia do novo coronavírus vem causando consequências catastróficas em todo o mundo.  Dessa forma, governos foram compelidos a adotar o isolamento o social como forma de combate a disseminação do vírus. Apesar de importante, essa medida tem impacto na economia, afetando principalmente micros e pequenos empreendimentos (MPEs). Neste artigo, é apresentado um relato de experiência acerca da execução do projeto Negócio Local, o qual consistiu na implementação de uma alternativa para divulgação de produtos e serviços de MPEs, através de uma plataforma online gratuita, como forma de impulsionar o desenvolvimento regional do município de Santa Luzia/Paraíba e região do Vale do Sabugi. Durante a execução do projeto, uma equipe do Instituto Federal da Paraíba, campus Santa Luzia, realizou a prospecção de potenciais empreendedores que desejassem inserir seus negócios no ambiente virtual. Em seguida, foram desenvolvidos websites para os MPEs, de forma completamente gratuita. Além disso, foram realizadas capacitações para que os próprios empreendedores fossem habilitados a administrar seus respectivos websites. Dentre os parceiros sociais do projeto, encontram-se empreendimentos do ramo alimentício e do setor de serviços. Por fim, as ações e resultados do projeto foram divulgados em mídias sociais.
MODELOS DE EXTENSÃO REPRESENTATIVOS DO DIFUSIONISMO, DIALOGISMO E TRANSFERENCISMO NA AMÉRICA LATINA
Authors: Medeiros Crisvalter Rogério De Araújo
Published: December 2022

Este trabalho tem o objetivo de identificar os modelos de extensão mais convergentes com as dimensões do difusionismo, dialogismo e transferencismo, dentre aqueles que são adotados nas universidades da América Latina, a partir de uma pesquisa exploratória realizada na base de dados Sistema de Información Científica Redalyc. O trabalho aborda a gênese da extensão universitária na Europa e a sua disseminação para outros continentes, apresentando os diversos modelos de extensão identificados nas instituições de educação superior da América Latina, comparando-os, entre si, e com as dimensões da extensão dialógica concebida por Paulo Freire (2013), e com os marcos conceituais dos contextos latino-americanos da extensão, através de uma metodologia comparativa (Quivy e Campenhoudt, 1995). Conclui-se que o modelo de extensão crítica (Tommasino e Cano (2016) representa os demais modelos de extensão de características dialógicas; o modelo de divulgação cultural e científica (Menéndez, 2017), representa o difusionismo acadêmico; sendo que os modelos voltados à vinculação empresarial são representados pelo de serviços a terceiros e inovação e transferência de tecnologia.
UM GRUPO DE ESTUDO COMO UM AMBIENTE DE PRÁTICAS BASEADAS EM EVIDÊNCIAS MATEMÁTICAS
Authors: Santos William De Souza
Published: December 2022

Em meio ao processo de desinformação que vem ocorrendo no mundo, se torna importante a criação de ambientes de discussão que possam propiciar à população o acesso a informações corretas. Nessa perspectiva, através de uma abordagem qualitativa, este artigo tem como objetivo, divulgar as ações realizadas através do projeto de extensão intitulado "Práticas Baseadas em Evidências Matemáticas" que tinha como fundamento, possibilitar um espaço de formação inicial e continuada de pesquisadores da área de matemática, demais interessados e entusiastas sobre a importância e a responsabilidade da matemática em diversos contextos. Como resultado, são apresentados os temas das reuniões realizadas de forma remota por este grupo de estudos com o intuito de facilitar o processo de difusão do conhecimento, bem como outros desdobramentos desta ação durante a execução deste projeto de extensão.
The Child and the Anthropocene: A Time Travel Narrative as a Means to Empower Children in the Face of a Global Pandemic
Authors: Colerick Edward
Published: December 2022

The following article looks at a contemporary children’s time travel story, The Dog Who Saved the World by Ross Welford, written and published just at the very outset of the COVID-19 epidemic. The novel is itself about an even more potentially dangerous epidemic which might have serious consequences in the near future for the whole of humanity. The author skilfully uses the narrative in order to include the child reader by replicating the mood and atmosphere of the current pandemic, thus, effectively empowering them against it. To achieve this, the author foregrounds what he considers to be “good” as opposed to “bad” technology and enables the child to comfortably deal with its complexities along with the complexity of time travel through scientific initialisms and other forms of abbreviation which children are highly familiar with (texting friends on smartphones or using the social media).
Haunting Time in Jesmyn Ward’s Sing, Unburied, Sing
Authors: Eyrolles Suchet Stéphanie
Published: December 2022

Jesmyn Ward’s Sing, Unburied, Sing is a story about the past as well as about the present. It is peopled not only by characters living in the present South but also by ghosts representing past racial injustice. These ghosts are the manifestation of past racial brutality, the sign of the past haunting the present. But Sing, Unburied, Sing presents a temporal aporia: the past is separate from the present, hence the presence of ghosts as a link between the two temporalities but they are also merged through the present remains of the past: the Parchman prison or the present racial discrimination Jojo and his family have to cope with. The story thus seems to have a temporal dimension of its own. Following French philosopher Paul Ricoeur’s theory presented in his Time and Narrative, I will try to show that the different narrators are telling their story, not only to try to make sense of this temporality they exist in, but also to try to achieve a form of narrative identity that reinforces the African American community.
A Comprehensive Approach to Investigating Fluorine-Bearing Gas Mixtures
Authors: Andreev A.A. , Pashkevich D.S. , Bryankin D.V. , Belov N.A. , Kambur P.S. , Kapustin V.V. , Zhuravkov S.P.
Published: December 2022

An integrated method is proposed for examining the compositions of fluorine-bearing gaseous mixtures, which allows for determining the concentration of HF, F2, N2, O2, CO2, CF4, and C2F6 in these mixtures. The concentration of hydrogen fluoride is determined by its sorption on sodium fluoride followed by the determination of the fluoride ion by the potentiometric method. The lower threshold of determination of hydrogen fluoride is found to be 0.09 vol.%. The concentrations of N2, O2, CO2, CF4, and C2F6 are determined by the gas chromatographic method using a thermal conductivity detector. The proposed gas-chromatography method offers a quantitative measurement of the concentration of N2, O2, CO2, CF4, and C2F6 at the lower limits of detection of 0.008, 0.012, 0.011, 0.009, and 0.019 vol.%, respectively. Based on the developed method, the compositions of a standard fluorine-nitrogen (10 vol.%) and anodic gas samples, synthesized in a laboratory electrolyzer at the National Research Tomsk Polytechnic University and in an industrial electrochemical reactor at JSC Siberian Chemical Plant (Russia), are studied.
Mathematical Modeling of the Corrosion Behavior of Austenitic Steels in Chloride-Containing Media During the Operation of Plate-Like Heat Exchangers
Authors: Narivs’kyi O. , Atchibayev R. , Kemelzhanova A. , Yar-Mukhamedovа G. , Snizhnoi G. , Subbotin S. , Beisebayeva A.
Published: December 2022

Mathematical models that describe the dependences of the critical temperatures of pitting formation of AISI 304, 08Kh18N10, AISI 321, 12Kh18N10T steels in model circulating waters with pH 4…8 and chloride concentrations from 350 to 600 mg/l on their chemical composition and structure have been developed. They are based on linear squares regressions and a feed-forward neural network for reduced feature numbers. Using the developed mathematical models, it was found that the critical pitting temperatures of these steels increase with an increase in the pH of the circulating water, the number of oxides up to 3.95 μm in size, the average distance between titanium nitrides, the Cr content and a decrease in the concentration of chlorides in the circulating waters, the average distance between oxides and average austenite grain diameter. At the same time, it was found that the geometric dimensions of the steel structure most intensively affect their pitting resistance in circulating waters, and the effect of their chemical composition is minimal and is determined by the amount of Cr, which contributes to an increase in the pitting resistance of steels, probably increasing the solubility of nitrogen in the austenite solid solution. It is proposed to use the developed mathematical models to select the optimal heats of these steels for the production of heat exchangers and predict their pitting resistance during their operation in circulating waters.
Preliminary Study and Assessment of Drinking Water from Almaty, Kazakhstan
Authors: Sailaukhanuly Y. , Popova A. , Mansur T. , Bexeitova K. , Azat S. , Toshtay K. , Tovassarov A. , Tasmagambetova A.
Published: December 2022

Drinking water samples from eight districts of Almaty, Kazakhstan was collected and physical and chemical analysis of the samples was carried out. Quality indicators of drinking water, such as organoleptic characteristics of water (smell, taste, color, and turbidity), general characteristics (pH, total hardness, permanganate demand, and dry residue), inorganic substances (cations and anions) and contaminants (heavy metals and total petroleum hydrocarbons) were determined, except pesticide residues which will be analyzed for further analysis with a wide range of pollutants. According to all indicators obtained for all districts of Almaty, the anthropogenic impact on drinking water in Almaty districts is assessed as low, not exceeding the permissible maximum allowable concentrations (MAC) values, and drinking water in Almaty corresponds to the approved standards and rules for drinking water of Kazakhstan. Despite of the fact that studied pollutants are below their MAC values, they still pose threat to public health due to their accumulative properties. The study of drinking water in the districts of Almaty made it possible to assess the ecological state in the studied districts of Almaty, as well as to propose recommendations for improving the quality of drinking water in areas where water quality indicators are closer to their MAC values.
The existence of the Ahmadiyya in Indonesian democracy: a struggle for survival in the midst of the Islamic-movement competition
Authors: Usman M. , Widodo Aris , Aini Shofwatul
Published: December 2022

This article attempts to portray the competition of forces in the Indonesian democratic system, with the Ahmadiyya movement as the test case for the “contestation”. This article takes into account the reformation era as the landscape of the study, since this era opens a relatively wider opportunity for many entities to freely express their ideas and actions. Exploring the socio-political approach, this study comes up with the following findings: first, in the sociological domain, as predicted by Dawam Rahardjo, moderates defeat radical Indonesian Islam as the former outnumber the latter. However, in the political domain, as pointed out by Martin van Bruinessen, since the moderate Islam is just a silent majority, then the radical Islam wins the competition - marked by the issuance of the SKB Tiga Menteri, because the factor at work in the winning of this political competition is more on the “logic of power”, rather than the “power of logic”. The victory of the radical Islam in the political domain in turn implies at the failure of the Ahmadiyya movement in its struggle for survival in Indonesia.
Prediction of severe post-castration syndrome in women after surgical menopause
Authors: Butina L.I. , Olshevska O.V. , Shelestova L.P. , Olshevskyi V.S.
Published: December 2022

Objectives: prediction of severe post-castration syndrome (PCS) in women after surgical menopause.Materials and methods. The study included 67 surgically menopausal women aged 45–55 years who underwent surgical hysterectomy with or without appendages (the main group) and 30 naturally menopausal women (the comparison group). The method of constructing and analyzing multifactorial mathematical models was used to identify risk factors associated with the development of severe PCS in women after surgical menopause and assess its impact on the severity of PCS. 12 clinical and morphological factors were considered in the analysis. The severity of the PCS in women after surgical menopause was evaluated one month after surgery and symptoms of climacteric syndrome in women with natural menopause were assessed according to the modified Kupperman index.Results. Surgical menopause significantly increases the risk of severe PCS in comparison with natural menopause, when climacteric syndrome develops (p < 0.001). The risk of severe PCS increases with the removal of the uterine appendages, inflammatory changes in the uterine appendages, the ovarian cyst (p < 0.001), and uterine fibroids (p = 0.04). Three factor signs remain after selecting a set of independent signs in a multifactorial model for predicting the risk of severe PCS: removal of the uterine appendages (p < 0.001), inflammatory changes in the uterine appendages (p = 0.006), ovarian cyst (p = 0.082). Based on these factor signs, we can accurately predict the risk of severe PCS (AUC = 0.951, 95% CI 0.89–0.98).Conclusions. Women with surgical menopause after the uterine appendages removal, with inflammatory changes in the uterine appendages, and ovarian cysts are at risk for the development of severe PCS and therefore it is advisable for them to include in the complex treatment of PCS medicines which reduce inflammatory changes in the uterine appendages and restore immunological reactivity.
Evaluation of the complex approach effectiveness of atrophic colpitis treatment in menopausal aged women from the pathogenetic view
Authors: Beniuk V.O. , Goncharenko V.M. , Usevych I.A. , Oleshko V.F. , Momot A.A. , Puchko M.S. , Veretelnyk Y.I.
Published: December 2022

Objectives: to determine the status of connective tissue and ionized magnesium value before and after complex treatment of atrophic colpitis with the CO2 laser in menopausal women. Materials and methods. 160 women with atrophic colpitis took part in this prospective study and were divided into three groups depending on the therapy. The main group included 55 patients who underwent CO2 laser therapy. The comparison group included 40 women who underwent CO2 laser therapy and local hormonal treatment with suppositories containing estriol and magnesium saturation by magnesium lactate dihydrate. The control group consisted of 65 women who received only suppositories containing estriol. The duration of treatment was 12 months. In addition to general clinical studies, markers of collagen synthesis (Total PINP, Total PІІІNP), collagen resorption marker (Pyriliks-D), as well as the ionized magnesium value in blood serum were determined in all patients.Results. A significant increase and steady retention at the physiological level of the average value of the Total PINP in the comparison group was revealed. The average level of the Total PIІІNP in patients of this group underwent a significant decrease and remained steadily at the upper limit of the physiological norm. A significant decrease and stable retention at the physiological level of the Pyriliks-D was noted in the comparison group against the background of the proposed therapy. Correction of magnesium status in the comparison group leads to a reliable and stable increase in the Mg+ ions concentration in blood serum.Conclusions. The inclusion CO2 laser in combination with local hormonal therapy and long-term correction of mineral metabolism in the treatment of the comparison group led to the stable normalization and prolonged retention at the physiological level for 12 months of the procollagen type I N-terminal propeptide, procollagen type III N-terminal propeptide, collagen resorption marker Pyriliks-D and a significant increase in magnesium concentration. This is confirms the effectiveness of the proposed complex.
Role of prenatal microbiota in fetal programming
Authors: Zhuk S.I. , Shchurevska O.D. , Yefisko V.M.
Published: December 2022

According to the concept of D. Barker, the intrauterine period is decisive in the programming of postnatal pathology, which can manifest during life. Among the factors of fetal programming, the microbiota plays an important role, but many aspects are still debatable.Objective: analysis and generalization of literary data devoted to the study of the association between the human body and microorganisms, their characteristics during pregnancy and their role in the health and pathology.According to the literature analysis, the article provides data on the non-sterility of the intrauterine environment and ways of its formation. The dynamics and features of “healthy” biotopes of intestines, vagina, mouth and placenta during pregnancy are considered. The main ways of fetus colonization by microorganisms are described, in particular, a major role is given to oral microflora. The effects of prenatal microbiota in physiological and complicated pregnancy, namely in preeclampsia, gestational diabetes, and miscarriage are discussed.Evidence is provided that microbial metabolites are capable of epigenomic modifications that alter fetal metabolism. This is further realized in the diseases of civilization. In addition, there are 360 times more bacterial genes than human genes. Therefore, they are called the “second genome” of a human, which can be changed according to needs. Modern research points to the essential importance of the maternal environment impact on the formation of microflora in fetus and pathology programming, and this process begins in utero. Maternal microbiota in normal and pathological conditions has a direct and indirect effect on the fetus through the immune reactions of the body or microbial metabolites penetrating through the placenta.Conclusions. The importance of microbiota in the metabolic processes of the fetus and newborn is extremely important. Microbiota also plays a significant role in the main pathophysiological aspects of programmed pathology. The development of correct preventive and therapeutic measures to modify the “healthy” microbiota during periods of its active formation should be a perspective for further research. This will allow it to be corrected taking into account the characteristics of individual biotopes.
The prospects for the use of artificial intelligence in obstetrics in Ukraine
Authors: Zhylka N.Y. , Shcherbinska O.S. , Netskar I.P.
Published: December 2022

In Ukraine, there is a steady trend towards an increase in the incidence of various forms of hypertensive disorders, both mild and severe, among pregnant women. Preeclampsia and eclampsia are severe forms of hypertensive disorders during pregnancy, the rates of which tend to increase, and lead to severe morbidity, disability and mortality in both women and newborns.The article reveals the question of the artificial intelligence (AI) use in modern midwifery in the national health care system of Ukraine in order to prevent pregnancy complications, in particular eclampsia. Implementation of AI systems in medicine is one of the most important modern trends in global healthcare. AI technologies are fundamentally changing the world health care system, allowing to radically rework the system of medical diagnostics, the development of new medicines, and also to generally improve the quality of health care services while simultaneously reducing costs for medical clinics. AI allows analyzing placenta samples and calculating the risk for a woman’s health in future pregnancies. The system is designed to help obstetrician-gynecologists, who will find it useful to forecast possible complications of future births. The use of AI in clinical practice makes it possible to identify the most serious prognostic signs of damage to blood vessels of the placenta, which is called decidual vasculopathy in preeclampsia and eclampsia. If preeclampsia is detected at an early stage, the patient can be treated before symptoms appear.AI use must be in compliance with six principles of the WHO in order to limit risks and increase the possibilities of using AI technologies: protection of human autonomy; promotion of human well-being and safety and public interests; ensuring transparency and comprehensibility; promoting responsibility and accountability; ensuring inclusiveness and fairness; promotion of AI in accordance with the principles of adaptability and sustainable development. Adherence to the ethical principles of AI gives the green light for the development of modern health care systems. It can become an effective method of preventing eclampsia in pregnant women, women in labor, and newborns and preserving their health and life.
Clinical and ultrasound characteristics of the health status of fertile aged women, who smoke and have metabolic syndrome
Authors: Podolskyi Vol. V. , Podolskyi V.V. , Buhro V.V.
Published: December 2022

Objectives: to identify clinical and ultrasound indicators that can determine the need for further examination of fertile aged women who smoke and have metabolic syndrome (MS) regarding the risk of developing somatic pathology or diseases of the reproductive system.Materials and methods. 2 groups of women of fertile age were examined: the first group consisted of 20 women who smoked with MS, the second group included 20 women who smoked without MS. All women were interviewed using a specially designed general and reproductive health questionnaire. Ultrasound examination of the abdominal cavity and pelvic organs was performed using convex and transvaginal sensors according to existing examination protocols.Results. Women of the first group had a higher body mass index and other obesity parameters, which is typical for MS. Women of the second group smoked more cigarettes per day. The identified early onset of menstrual function in women with MS may be a manifestation of hormonal homeostasis disorders at the end of puberty with a predominance of estradiol secretion and insufficient progesterone synthesis in the second phase of the menstrual cycle. A significant amount of blood loss during menstruation and painful menstruation in women of the first group may be a manifestation of adenomyosis, which confirms by echo-positive and echo-negative inclusions in the myometrium and thickening of the uterine walls. In most patients with MS ultrasound showed multifollicular ovaries, which may point at polycystic ovary syndrome, given changes in body mass index and ovarian structure as a response on hyperestrogenemia. Prolonged manifestation of MS also negatively affected the abdominal organs, as evidenced by echo-positive inclusions in the liver and pancreas parenchyma, which is a manifestation of inflammatory diseases of these organs.Conclusions. The combination of prolonged smoking and metabolic syndrome leads to more pronounced changes in the reproductive system and abdominal organs, which in turn expands the range of recommended methods of instrumental examination for such women.
Menopauseal hormonal therapy and the risk of breast cancer in the light of new data
Authors: Yefimenko O.О.
Published: December 2022

Menopause is a natural and inevitable physiological process of the decline of reproductive function due to a decrease in ovarian function, which every woman has to face after about 45–60 years. During this period of hormonal changes the female body needs support more than ever, because the quality of life of a modern woman directly depends on it.The question of the menopausal hormone therapy (MHT) safety in relation to the risk of breast cancer is a perennial subject of research, studied and debated in the medical literature for more than 20 years. During this time, several different studies on this issue were conducted. In this review we describe previous insights along with recent research using estradiol and natural micronized progesterone in MHT regimens. The body of evidence suggests that modifiable lifestyle factors (such as obesity and alcohol consumption) rather than combined MHT are the real breast cancer risks; combined MHT containing estradiol and micronized progesterone was not associated with an increased risk of breast cancer; when prescribing MHT, micronized progesterone may be a safer progestogen. The clinical significance of the obtained results is also discussed.
Efficiency of treatment and diagnostic algorithms in the rehabilitation program of women after hysterectomy with opportunist salpingectomy due to uterine myoma
Authors: Proshchenko O.M. , Ventskivska I.B.
Published: December 2022

Objectives: to determine the effectiveness of the rehabilitation program in women of reproductive age with uterine fibroids for correction of genitourinary syndrome after hysterectomy with opportunistic salpingectomy.Materials and methods. 160 women were examined after hysterectomy with fallopian tubes. State of the urogenital tract and urogenital dysfunction researched with the using the POP-Q system, the Barlow scale, vaginoscopy. Also it was used evaluation of the vaginal pH and mucosal microbiota state, assessment of the vaginal health index according to G. Bochmann, assessment of the impact of vulvovaginal symptoms on the life’s quality with the MOS SF-36 questionnaire in the dynamics of the postoperative period. The treatment algorithm included local preparations of hyaluronic acid, lactobacillus preparations in combination with vitamin D solution, in case of a severe course – topical estrogens, in case of vasomotor symptoms – estradiol 50 μg/day and vitamin D 4000 IU daily or 20,000 IU once a week.Results. Manifestations of genitourinary syndrome were revealed 1 year after surgery, namely: hypotrophy of the vaginal mucous membrane in 36.3% of women, urinary incontinence in almost a third of patients, prolapse of the vaginal walls of the I–II degree in 8.8% of women, a pathological microscopic picture in 68.1% of female. The proposed algorithms in the rehabilitation program made it possible to eliminate or reduce the severity of genitourinary symptoms 5 years after hysterectomy, in particular, to reduce the frequency of vulvovaginal atrophy by 25%, to normalize the biocenosis and pH of the vaginal contents, to reduce the clinical manifestations of urination disorders (pollakiuria and nocturia by 14% and 12,8%, respectively), feeling of incomplete emptying of the bladder by 12.9%, stress urinary incontinence by 17.9%, vaginal prolapse by 13.3% compared to the group with standard postoperative management.Conclusions. Hysterectomy with opportunistic salpingectomy for uterine fibroids has a positive effect on the life’s quality of patients by improving the physical comfort due to the reduction of clinical symptoms of uterine fibroids. However, changes in the quality of life after surgical intervention associated with disturbances in the psycho-emotional sphere were recorded in 49.4% of women, including those provoked by the manifestation of genitourinary syndrome in 19.3%. The proposed algorithm in the rehabilitation program made it possible to reduces the severity of genitourinary symptoms.
Components and their assessment in different biogas slurries for enhanced waste management
Authors: NAMLI Ayten , AKÇA Hanife , AKÇA Muhittin Onur
Published: December 2022

In this study, liquid fermented wastes from 15 licensed biogas plants located within different regions of Türkiye were determined and the parameters that are important to waste management evaluations were revealed. Accordingly, some physical, chemical, and biological analyses include moisture, dry matter (DM), organic matter (OM), pH, EC, total N, P, K, Salmonella, Escherichia coli, E.coli O157:H7, and Enterobacteria were conducted. Spearman’s correlation analysis was conducted to determine the relationship among the results, and a regression analysis was conducted to reveal the effect of the results on each other. In the wastes, DM values were between 0.53-9.71%, OM values were between 0.53-7.76%, N contents were between 0.10-0.74%, P contents were between 0.04-0.22%, K contents were between 0.15-0.56%, EC values were between 1.50-6.51 dS m-1, B contents were between 16.96-34.63 mg kg-1, and Na contents were between 0.11-0.40%. A correlation analysis was conducted to reveal the relationship of OM and DM to other parameters. OM content had a significant correlation with N (73.9%), P (80.4%9, Fe (71.4%), Mn (75.7%), EC (53.2%), K (60.7%), and Mg at 72.1%. The DM contents had a significant correlation with N (68.2%), P (95.4%), Cu (60.0%), Fe (88.2%), Mn (94.3%), Zn (67.5%), EC (76.1%), K (81.4%), and Mg at 83.9%. A significant regression model and the variances of DM and OM variables were 37.8 and 24.8% for N (%), 61.7 and 31.5% for P (%), 53.9 and 22.4% for K (%), 46.6 and 23.8% for Ca (%), and 70.0 and 45.7% for Mg (%), respectively. Finally, these observations should be used to demonstrate the usability of liquid fermented wastes for agricultural purposes.
Seasonal fluctuations in phthalates’ contamination in pond water: A case study
Authors: RAJPUT Sneh , KUMARİ Arpna , SHARMA Ritika , RAJPUT Vishnu D. , MİNKİNA Tatiana , ARORA Saroj , KAUR Rajinder
Published: December 2022

Phthalates are endocrine disruptors, reported to cause deformities and reproductive damages in animals. Numerous studies reported the presence of phthalates in water samples of rivers, wetlands, and estuaries, while the scenario in case of ponds is different, however they are reported as an integral part of biosphere. In this study, the level of phthalates’ contamination in the water samples collected from the different ponds of Amritsar district for four consecutive seasons in two years was analysed. The maximal level of phthalate contamination was found in samples collected during the monsoon season (July 2015) of first year of sampling followed by post-monsoon (October 2015) and winter season (January 2016). S8 sampling site was found to be the most phthalate contaminated site followed by S1=S11>S2=S9=S4=S5=S7>S6=S3>S10. Benzyl butyl phthalate was most abundant (found in 32% water samples) followed by di-n-butyl and dimethyl phthalate, while diallyl phthalate and diethyl phthalate were not detected. The two main drivers for these seasonal variations were observed to be temperature and precipitation. Hence, this data will be useful to explain the temporal and spatial distributions of phthalates in aquatic ecosystem, as well as to devise cost-effective ways to reduce their ecological footprints.
Identification of species of the genus Quercus L. with different responses to soil and climatic conditions according to hyperspectral survey data
Authors: DMİTRİEV Pavel , KOZLOVSKY Boris , DMİTRİEVA Anastasiya , LYSENKO Vladimir , CHOKHELİ Vasily , MİNKİNA Tatiana , MANDZHİEVA Saglara , SUSHKOVA Svetlana , VARDUNİ Tatyana
Published: December 2022

Soil standing may be studied indirectly using remote sensing through an assessment of state of the plants growing on it. The ability to evaluate the physiological state of plants using the hyperspectral survey data also provides a tool to characterize vegetation cover and individual samples of woody plants. In the present work the hyperspectral imaging was applied to identify the species of the woody plants evaluating the differences in their physiological state. Samples of Quercus macrocarpa Michx., Q. robur L. and Q. rubra L. were studied using Cubert UHD-185 hyperspectral camera over five periods with an interval of 7-10 days. In total, 80 vegetation indices (VIs) were calculated. Sample sets of values of VIs were analyzed using analysis of variance (ANOVA), principal component analysis (PCA), decision tree (DT), random forest (RF) methods. It was shown using the ANOVA, that the following VIs are the most dependent on the species affiliation of the samples: Carter2, Carter3, Carter4, CI, CI2, CRI4, Datt, Datt2, GMI2, Maccioni, mSR2, MTCI, NDVI2, OSAVI2, PRI, REP_Li, SR1, SR2, SR6, Vogelmann, Vogelmann2, Vogelmann4. VIs that are effective for the separation of oak species, were also revealed using the DT method – these are Boochs, Boochs2, CARI, CRI1, CRI3, D1, D2, Datt, Datt3; Datt4, Datt5, DD, DDn, EGFN, Gitelson, MCARI2, MTCI, MTVI, NDVI3, PRI, PSND, PSRI, RDVI, REP_Li, SPVI, SR4, Vogelmann, Vogelmann2, Vogelmann3. PCA and RF methods reliably differentiated Q. rubra from Q. robur and Q. macrocarpa. Q. rubra, unlike other species, was under stress from the impact of soil pH against the background of drought. This was manifested in leaf chlorosis. Influence of the environmental stress factors on the reliability and efficiency of species identification was demonstrated. Q. robur and Q. macrocarpawere were poorly separated by PCA and RF methods all over the five periods of the experiment.
KONFERENCIA A TANULÁSRÓL ÉS A TÁRSADALOMRÓL
Authors: Mező Ferenc
Published: December 2022

Az Eszterházy Károly Katolikus Egyetem volt a helyszíne a „Tanulás és Társadalom” Interdiszciplináris Nemzetközi Konferenciának 2022. november 10-12.-én. A konferencián 12 ország 331 résztvevőjének 161 előadását tették közzé 16 szekcióban. A rendezvény a MEC_SZ_141117 projekt keretében valósult meg, mely projekt az Innovációs és Technológiai Minisztérium Nemzeti Kutatási Fejlesztési és Innovációs Alapból nyújtott támogatásával, a MEC_SZ_21 pályázati program finanszírozásában valósult meg. Jelen tanulmány egy rövid beszámoló a konferenciáról.