bluuebunny/crossref_metadata_2025 huggingface dataset:
USO DE ACTINOBACTERIAS EN LA SÍNTESIS DE NANOPARTICULAS METALICAS CON ACTIVIDAD TERAPÉUTICA
Authors: Zarate Jiménez Ana Cecilia , Ortega Cabello Lucía , Hernández Vázquez Liliana , Hamdan Partida Aida
Published: February 2025

Las actinobacterias son un grupo diverso de bacterias Gram positivos con morfología variada, que incluye principalmente las formas cocoides. Las cuales han capturado la atención debido a su capacidad multifacética en diversos entornos como es el ambiental, alimentaria y farmacéutica. Sin embargo, es en este último donde revelan su mayor potencial, ya que los metabolitos secundarios que liberan poseen propiedades antitumorales, antivirales, antibióticas y antifúngicas. No obstante, otro potencial de las actinobacterias es la síntesis verde, facilitada por antioxidantes derivados de sus metabolitos secundarios. Esto permite la producción de nanopartículas metálicas (mNP) estables en diversas formas y tamaños. Están principalmente compuestas de oro y plata; A las cuales se les ha encontrado aplicaciones en la detección temprana de enfermedades, el transporte selectivo de fármacos y la promoción de la formación de nuevos tejidos. Además, en el ámbito farmacéutico, muestran propiedades terapéuticas como antibióticos, antivirales y antitumorales. Estas características hacen de las mNP herramientas versátiles y prometedoras en diversas áreas tanto científicas como tecnológicas. Sin embargo, también conlleva desafíos éticos, ambientales y en la seguridad en su uso especialmente en aplicaciones médicas. La estandarización de la síntesis y la comprensión de cómo estas nanopartículas interactúan con el entorno son esenciales para su producción a gran escala así como en su aplicación práctica. En última instancia, la investigación continua tanto en las actinobacterias como en las mNP que prometen llevarnos a un futuro donde estas brindan soluciones innovadoras y sostenibles para los desafíos que enfrenta la humanidad.
ECLIPSES SOLARES Y COMPORTAMIENTO HUMANO: UNA MIRADA A LOS PROCESOS DE COMPORTAMIENTO SUPERSTICIOSO
Authors: Carro Pérez Ennio Héctor
Published: February 2025

La conducta supersticiosa no es un comportamiento necesariamente asociado a lo “mágico” o “místico” sino producto de una circunstancia accidental. En el presente trabajo, se describe de manera general el proceso de adquisición de conducta supersticiosa, y como estos procesos se encuentran presentes en todo momento en la vida de las personas. Se analiza como estas conductas pueden producirse ante fenómenos astronómicos como los eclipses solares o la aproximación de cometas a la Tierra.
DISEÑOS DE INVESTIGACIÓN. EL COACHING METODOLÓGICO COMO ESTRATEGIA
Authors: Buttén de León Marcial Ranulfo , Hernández Barrera María Josefina
Published: February 2025

La Dra. Angelica Mendieta, quien es autora y coautora de más de 30 libros, nos presenta -una ruta crítica y reflexiva en el texto denominado “Diseños de Investigación, el coaching metodológico como estrategia” (2015)-. A través de seis capítulos nos indica cómo afrontar un proyecto de investigación.
DE VUELTA A LOS PRINCIPIOS: UNA REVISIÓN A LA OBRA DE WILLIAM JAMES
Authors: Sánchez Carballo Alfredo , Reyes González Rosa Isela
Published: February 2025

A lo largo de nuestra experiencia con la lectura, hemos notado que un texto de ciencias sociales, humanas o del comportamiento se convierte en un clásico cuando logra algo más que ser un simple trabajo académico. Estas obras se distinguen por su calidad literaria  y accesibilidad que trasciende las fronteras de su disciplina. Es decir, su lenguaje es claro a pesar de la especialización de los temas que tratan. Pensemos en obras como El Capital de Karl Marx, La Condición Humana de Hana Arendt, Pensamiento y Lenguaje de Lev Vigotsky, Economía y Sociedad de Max Weber, entre otros tantos. En lo que podría extenderse una lista innumerable también ha ganado un espacio el libro titulado Principios de Psicología de William James: obra que cumple con las dos características enunciadas.
INCLUSIVE DEVELOPMENT PROCESS IN THE PAKISTAN ECONOMY
Authors: Khan Sardar Javaid Iqbal , Khan Sardar Adil Iqbal , Khan Muhammad Imran , Nasir Rashid , Ayub Rizwan
Published: February 2025

Article focuses mainly on the inclusivity of Pakistan's economy's development and growth processes. The study presents the ideas behind inclusive growth and the inclusive development This aindex, as well as how they apply to established, emerging, and particularly Pakistan economy. The current body of literature focuses on factors that influence economic growth and strategies to improve it. Nonetheless, this ignores the benefits of growth for society. In prior decades, the distribution component of economic progress was disregarded. Consequently, the world is unable to reap the rewards of economic expansion. The Asian Development Bank's 2011 inclusive development and growth index is used in this study. To find out if Pakistan's economic expansion offers equitable chances to all members of the populace. The performance of the inclusive growth index's of sixteen indicators were evaluated from 1978 to 2014. The paper's conclusion demonstrates that inclusive growth in Pakistan is generally mediocre. In Pakistan, inclusive growth is on the rise. In Pakistan, distributive development strategies can be used to promote inclusive development while also accelerating economic growth in an equitable manner.
COMMUNICATION STRATEGIES AND CUSTOMER LOYALTY DURING BANKING M&A
Authors: Nahar Garima Singh , Gond Hrishi Kumar , Singh Amarendra Pratap , Yadav Vinay Kumar
Published: February 2025

Mergers and acquisitions (M&As) have become a defining feature of the banking sector, offering institutions opportunities for market expansion and financial growth. However, these transactions often pose significant challenges in customer retention, with studies indicating that banks can lose up to 30% of their customer base during the transition. This research examines the role of strategic communication in mitigating customer attrition and fostering trust during banking M&As.Utilizing a mixed-methods approach, this study analyzes five major banking M&As between 2018 and 2023, focusing on how communication timing, channel selection, and message content influence customer loyalty. Quantitative data on customer retention rates and engagement metrics were supplemented with qualitative insights from structured interviews with banking executives and communication strategists. The findings reveal that early, transparent, and personalized communication significantly improves customer retention. Banks that implemented proactive, multi-channel communication strategies experienced a 25% higher customer retention rate than those employing traditional, reactive approaches.The study highlights key success factors, including the effectiveness of digital channels such as mobile banking notifications and online portals, the impact of trust-building messages emphasizing service continuity, and the importance of segment-specific communication tailored to retail, business, and high-net-worth customers. Additionally, transparent disclosures regarding integration timelines and customer impact emerged as critical drivers of customer confidence.This research contributes to both theoretical understanding and practical applications in banking communications, offering actionable insights for financial institutions navigating M&As. By integrating communication as a core component of M&A strategy, banks can enhance customer retention, protect revenue streams, and ensure long-term institutional stability. Future research could explore the long-term effects of communication strategies on customer behavior and the role of emerging digital communication technologies in post-merger integration.
THE ROLE OF ENGLISH IN INDIA’S LITERARY FESTIVALS AND CULTURAL DIALOGUES
Authors: Sarkar Himadri
Published: February 2025

Language is one of the most important components of identity and power, which plays diverse roles, especially in postcolonial countries, because people’s language use divulges historical, cultural, and even political contexts. Indian English literature is a good example of this; writers recreate themselves and the postcolonial world through the English language, which they were oppressed with. Hence, instead of perceiving the use of English as a colonial imposition, Indian English writers have made it very vibrant and resonant for cultural representation and Indian identity construction in today’s globalised world. Indian English literature is known for using code-mixing, code-switching and incorporating the local dialects, as India is a multilingual and socially diverse nation. This way, it is possible to achieve the representation of Indian ethos in literary works and mould tradition and modernity. Salman Rushdie, Arundhati Roy, Vikram Seth, as well as Jhumpa Lahiri also use language not only as narration as a linguistic means for imparting narrative but also as a platform to create further messages concerning displacement, biculturalism, the marginalisation of the Indian society and the possible modes of fighting it, respectively. In this paper, I am going to analyse how these Indian English writers employ language to claim their ethnic alterity to the English language, as well as to resist social hierarchy systems from local and global perspectives and represent the diversification of Indian regions. This creed of cultural intertwining and the role of language as a mediator between the spiritual and the material, the people’s past and present, and regional and global tendencies become evident in the selected literary works. By making their English Ian English, Kureishi and others seek to revitalise the language in Indian writing in English, which, in response, writes back to the imperialist language and successfully makes it a democratic language of the oppressed.
कश्मीर केंद्रित हिंदी उपन्यासों में विस्थापन की त्रासदी ;शिगाफ़ के विशेष संदर्भ मेंद्ध
Authors: Kumar Prabhakar
Published: February 2025

कश्मीर जिसे ष्पृथ्वी का स्वर्गष् कहा जाता हैए वह केवल प्रकृति.सौन्दर्य के कारण ही नहीं अपितु विभिन्न जातिए धर्मए समुदायों के परस्पर प्रेम और सौहार्द के साथ रहने के कारण कश्मीर को ष्भारत का स्वर्गष् कहा जाता है। चूंकि कश्मीर का इतिहास ष्पुनरावृत्तियों का इतिहासष् रहा है। इसीलिए समय.समय पर यहाँ राजनीतिक अस्थिरता और उथल.पुथल भी देखा जा सकता है। कश्मीर कर इतिहास में अलग अलग समय पर अलग अलग धर्म एवं समुदाय के शासकों ने शासन किया। जिनमें हिन्दूए बौद्ध और इस्लाम धर्म को मानने वाले कई प्रमुख थें।
BRIDGING ART AND SCIENCE: THE ROLE OF BOTANICAL ILLUSTRATIONS IN PLANT TAXONOMY
Authors: Jain Divya
Published: February 2025

Botanical illustrations have played a fundamental role in plant taxonomy by providing detailed representations of plant morphology and anatomy. This paper explores the historical evolution of botanical illustrations, from ancient herbal manuscripts to Renaissance-era scientific drawings and their influence on taxonomic classification systems like Linnaeus's binomial nomenclature. Despite the advancement of modern imaging tools and genetic analysis, traditional botanical sketches remain useful, particularly when physical specimens are unavailable. Using a qualitative research approach and comprehensive literature review, this study examines the transition of botanical illustrations from artistic expressions to essential scientific tools. It also emphasises their integration with modern imaging and molecular tools, highlighting their long-term importance in plant taxonomy.
Husband’s Nusyuz in Female-Initiated Divorce: A Mubadalah Perspective
Authors: Ahyu Ifada Azka , Jamilah Jamilah , Yusmita Yusmita , Malik Ilham Saeful
Published: February 2025

Many people believe that Nusyuz (marital disobedience) is only committed by wives against their husbands, overlooking the possibility of Nusyuz by husbands towards their wives. Similarly, the judges at the Banyuwangi Religious Court often interpret divorce cases initiated by wives as a sign of the wife’s Nusyuz, even when the divorce is caused by the husband’s Nusyuz. This forms the background of this research. The focus and aim of this study are to analyze the judges' perspectives at the Banyuwangi Religious Court regarding the consideration of a husband’s Nusyuz, the status of a husband’s Nusyuz in divorce cases heard at the court, and to evaluate the judges' views on Nusyuz through the lens of mubadalah (reciprocity in marriage). This empirical juridical research adopts a qualitative approach, utilizing interviews with judges at the Banyuwangi Religious Court. The data used in this study includes primary, secondary, and tertiary sources. The research findings reveal that: (1) The majority of judges at the Banyuwangi Religious Court consider a husband’s Nusyuz primarily through the concept of taklik talak (conditional divorce). (2) In divorce cases at the Banyuwangi Religious Court, judges often deny post-divorce rights to wives, assuming that a wife who files for divorce is guilty of Nusyuz. As a result, they do not grant post-divorce entitlements such as mut’ah (compensation) and iddah (waiting period) maintenance. Although most judges at the Banyuwangi Religious Court understand the concept of Nusyuz from a mubadalah perspective, they have yet to fully implement it in practice
Validation of Pasu-Pasu Raja Marriage through Itsbat Nikah in the Perspective of Positive Law and Islamic Law: An Analysis of the Tarutung Religious Court Ruling
Authors: Adipraya Reza Kresna , Harahap Mhd Yadi , Fatimah Fatimah
Published: February 2025

This study investigates the legal validation of pasu-pasu raja marriages, a traditional Batak Toba ritual, at the Tarutung Religious Court, particularly in cases involving converts to Islam. The research explores three primary issues: the legal status of pasu-pasu raja under Indonesian law and Islamic law, the requirements for validating such marriages for converts, and the judicial responses at the Tarutung Religious Court. Employing a normative juridical approach with case study analysis, the findings indicate that while pasu-pasu raja is not part of the formal Islamic marriage process, it can serve as a cultural complement to a legally valid Islamic marriage. Under Indonesian positive law, itsbat nikah (marriage validation) is permissible for convert couples, provided the marriage complies with Islamic principles and is free from legal barriers. Most Islamic scholars affirm the validity of non-Muslim marriages post-conversion, without the necessity of a new marriage contract. The Tarutung Religious Court aligns with this perspective, offering legal certainty to converts without mandating a new contract. This legal recognition is consistent with the principles of maqashid asy-syar'iyyah, which emphasize the welfare and legal legitimacy of marriages
Evaluation of the One Heart Education Program in the Motorcycle Engineering and Business Expertise Competency
Authors: Handepi Nogi , Wakhinuddin  , Maksum Hasan , K Arwizet
Published: February 2025

Vocational education plays a critical role in preparing students to meet industry demands and enter the workforce effectively. This study aims to evaluate the One Heart Education Program in the Motorcycle Engineering and Business expertise competency at SMKN 1 Luak District, focusing on context, input, process, and product aspects, using the CIPP evaluation model. The study examines whether the program has been managed optimally. Employing a mixed-method approach, the research uses purposive sampling, involving 36 respondents, 26 for quantitative data and 10 as qualitative informants. Data collection methods include questionnaires and interviews. The evaluation results show that the program achieved an overall score of 72.24, categorized as sufficient, indicating suboptimal management. In detail, the context aspect related to program objectives is rated as poor, though the environmental aspect is good. The input, process, and product aspects are also found to be lacking. Key recommendations include optimizing the context aspect by refining program goals, adopting a centralized approach in the input aspect to explore students’ potential, enhancing the learning process in the process aspect to better align with industrial standards, and improving outcomes in the product aspect. These improvements aim to enhance the overall effectiveness and impact of the One Heart Education Program.
UJI AKTIVITAS ANTIOKSIDAN DAN PENETAPAN KADAR KAFEIN PADA SEDUHAN TEH HIJAU DENGAN VARIASI WAKTU SEDUH
Authors: Aptika Oktaviana Trisna Dewi
Published: February 2025

Teh  hijau adalah  jenis  teh  non fermentasi. Senyawa kimia yang terkandung di dalam teh memiliki efek yang baik bagi kesehatan, diantaranya adalah kafein yang diyakini dapat menurunkan kadar asam urat dalam darah, serta katekin sebagai agen antioksidan. Konsumsi teh hijau oleh masyarakat sering dilakukan secara diseduh tanpa memperhatikan secara detil waktu lama penyeduhannya. Tujuan dari penelitian ini adalah untuk mengetahui kadar kafein serta aktivitas antioksidan pada seduhan teh hijau dengan variasi waktu seduh. Waktu penyeduhan yang digunakan yaitu 5, 10, 15, 20, 25 dan 30 menit. Penentuan kadar kafein menggunakan metode spektrofotometri UV-Vis diukur pada panjang gelombang 275 nm. Penentuan aktivitas antioksidan menggunakan metode DPPH (2,2-diphenyl-1-picrylhydrazyl) dengan spektrofotometer UV-Vis diukur pada panjang gelombang 515,4 nm. Kadar kafein pada waktu penyeduhan 5, 10, 15, 20, 20 dan 30 menit berturut-turut yaitu 64,20±8,66 mg/g; 69,02±4,31 mg/g; 93,97±0,20 mg/g; 98,97±7,33 mg/g, 90,02±0,34 mg/g dan 52,73±3,84 mg/g. Hasil uji antioksidan dinyatakan dalam nilai IC50 berturut-turut sesuai lamanya waktu seduh yaitu 91,32±5,43 mg/L; 42,22±6,24 mg/L; 52,18±3,63 mg/L; 55,97±3,67 mg/L; 80,84±4,22 mg/L; 81,29±7,88 mg/L.
FORMULASI DAN UJI AKTIVITAS ANTIBAKTERI SEDIAAN HAND SANITIZER EKSTRAK ETANOL DAUN SALAM TERHADAP BAKTERI STAPHYLOCOCCUS AUREUS
Authors: Putri Mega Karina , Rumyaan Esther Febriyanti , Sari Eni Kartika
Published: February 2025

Penggunaan hand sanitizer memiliki kekurangan yaitu kadar alkohol diatas 80% bersifat mudah menguap, menyebabkan kulit kering dan rasa terbakar. Oleh sebab itu, dapat diformulasikan menggunakan zat aktif bahan alam yaitu daun salam (Syzygium polyanthum) yang memiliki kandungan senyawa bersifat sebagai antibakteri. Penelitian ini bersifat eksperimental dengan tahapan meliputi pembuatan ekstrak daun salam, skrining fitokimia, pembuatan gel hand sanitizer ekstrak daun salam konsentrasi 10%, 15%, 20%, uji sifat fisik sediaan, uji aktivitas antibakteri Staphylococcus aureus. Data yang didapatkan berupa sifat fisik dan zona hambat antibakteri dianalisis statistik dengan uji One Way ANOVA. Hasil uji dari penelitian ini menunjukkan bahwa variasi konsentrasi ekstrak etanol daun salam (Syzygium polyanthum) dalam sediaan gel hand sanitizer mempengaruhi sifat fisik sediaan yaitu organoleptik, daya sebar, daya lekat dan pH. Gel hand sanitizer dengan variasi konsentrasi ekstrak etanol daun salam (Syzygium polyanthum) mempunyai aktivitas antibakteri Staphylococcus aureus dengan kategori zona hambat sangat kuat.
PEMANFAATAN KARBON AKTIF TEMPURUNG KELAPA SEBAGAI ADSORBEN DALAM MENURUNKAN KADAR TEMBAGA (Cu) PADA AIR SUNGAI SEBAMBAN
Authors: Rahmah Mulia , Alawiyah Tuti , Rohama  , Rahmadani
Published: February 2025

Sungai Sebamban merupakan salah satu sungai yang berada di Kabupaten Tanah Bumbu, Provinsi Kalimantan Selatan yang biasa digunakan masyarakat dalam kegiatan sehari-hari. Namun, sungai ini memiliki cemaran kadar tembaga (Cu) melebihi ambang batas yang telah ditetapkan. Penelitian ini bertujuan untuk memanfaatkan adsorpsi dari karbon aktif tempurung kelapa untuk menurunan kadar tembaga (Cu) pada Sungai Sebamban. Penelitian ini dilakukan menggunakan metode kuantitatif secara true-eksperimental, perlakuan pada sampel uji dengan rancangan penelitian post test only control group design, dianalisis menggunakan uji one way Anova dengan instrumen Spektrofotometri Serapan Atom (SSA). Hasil penelitian menunjukkan bahwa kadar tembaga (Cu) pada air Sungai Sebamban sebesar 25,06 mg/L. Setelah direndam menggunakan karbon aktif tempurung kelapa dengan variasi waktu 30 menit memiliki kadar sebesar 14,45 mg/L atau penurunan sebesar 41,97%, waktu 60 menit kadar sebesar 7,15 mg/L atau penurunan sebesar 71,46% dan waktu 120 menit kadar sebesar 1,52mg/L atau penurunan sebesar 93,93%. Berdasarkan hasil penelitian, terdapat pengaruh waktu terhadap pemberian karbon aktif tempurung kelapa.
The Immunostimulant Effect of Raspberry (Rubus idaeus) Fruit Ethanol Extract Through Carbon Clearance Index and Organ Index
Authors: Gandana Mohamad Vito , Lestari Fetri , Tri Laksono Bambang
Published: February 2025

Raspberry fruit ethanol extract is known to have strong antioxidant activity and which is related with immunostimulant activity. This study aims to determine the immunostimulant activity of ethanol extract of raspberry fruit.Raspberry fruit is macerated with 70% ethanol and concentrated using a rotary evaporator, then the phagocytosis index, spleen and liver index in mice are determined using the carbon clearence method.Based on the results obtained, it is known that all doses have immunostimulant activity because there are significant differences (p <0.05) between all doses against the negative control group with a dose of 400mg / kgBB having the highest value among the test groups and having moderate immunostimulant activity.
EVALUASI SEDIAAN GARGARISMA EKSTRAK ETANOL DAUN JERUK NIPIS (Citrus aurantiifolia) TERHADAP Streptococcus mutans
Authors: Asfari Fauziyyah  , Srie Rezeki Nur Endah  , Lina Rahmawati Rizkuloh
Published: February 2025

Ekstrak etanol daun jeruk nipis diketahui mempunyai pengaruh antibakteri terhadap Streptococcus mutans penyebab karies, sehingga cocok dibuat ke dalam sediaan gargarisma. Penelitian ini bertujuan untuk menghasilkan sediaan obat kumur berbasis ekstrak etanol daun jeruk nipis, serta mengetahui aktivitasnya terhadap bakteri Streptococcus mutans. Sediaan dikembangkan dengan empat formula yaitu F0 (basis), F1 (20%), F2 (25%) dan F3 (30%). Evaluasi sediaan meliputi uji organoleptis, uji homogenitas, uji pH, uji bobot jenis, dan uji viskositas. Uji aktivitas antibakteri sediaan gargarisma menggunakan chlorhexidine 0,2% sebagai pembanding, melalui teknik sumuran. Evaluasi membuktikan bahwa ekstrak etanol daun jeruk nipis dikembangkan menjadikan sediaan gargarisma. Hasil uji aktivitas sediaan gargarisma menunjukkan diameter ratarata daya hambat sebesar  F0 (0 mm), F1 (15 mm), F2 (15,6 mm), F3 (16,06 mm) dan kontrol positif (14,64 mm).
ESTRATÉGIAS EFICIENTES DE PREVENÇÃO E PROMOÇÃO DA SAÚDE NA ATENÇÃO PRIMÁRIA: ABORDAGENS INTEGRADAS PARA A QUALIDADE ASSISTENCIAL
Authors: ROCHA JOÃO PEDRO FEITOSA , ARARUNA JOSÉ FELLIPE LIMA , SOARES YAGO JOSÉ ALVES , SILVA FRANCISCA ANDREZA PASSOS , REIS GIOVANNA MARIA REBOUÇAS DOS , CONCEIÇÃO DAMARAELLEN PEREIRA , SÁ MATEUS SAULO DANTAS CORREIA E , SILVA MAYRA SOCORRO DE OLIVEIRA , ROCHA NÉLIO FERREIRA DA , SHIMOKAWA STEPHANY SAKURA ROCHA
Published: February 2025

A Atenção Primária à Saúde (APS) desempenha um papel fundamental na prevenção de agravos e na
promoção da saúde, garantindo equidade no acesso aos serviços e a sustentabilidade dos sistemas de saúde.
Este estudo analisou estratégias eficazes de prevenção e promoção da saúde, destacando abordagens
interdisciplinares, inovação tecnológica e impacto dos determinantes sociais. A metodologia adotada
baseou-se em uma revisão integrativa da literatura, considerando publicações científicas e diretrizes
institucionais entre 2015 e 2024. Os achados evidenciam que modelos assistenciais integrados, como a
Estratégia Saúde da Família (ESF), e o uso de tecnologias digitais, como telemedicina e inteligência
artificial, ampliam o acesso e a efetividade da APS. Além disso, a qualificação contínua dos profissionais
melhora a adesão a diretrizes clínicas e fortalece a relação com a comunidade. Contudo, desafios como
desigualdades sociais, subfinanciamento e resistência à transformação digital ainda comprometem a
eficácia das estratégias preventivas. Conclui-se que o fortalecimento da APS requer políticas públicas
sustentáveis, investimento em inovação e abordagem intersetorial para garantir um sistema de saúde mais
resolutivo e equitativo.
Measurement of County Relative Poverty, Spatial and Temporal Evolution and Risk Evaluation of Return to Poverty in Shaanxi Province Under the Perspective of Rural Revitalization
Authors: Wu Ruixi
Published: February 2025

Against the background of rural revitalization, this study makes an in-depth analysis of the measure, evolution and the risk of returning to poverty in the counties of counties in Shaanxi Province. By combining quantitative and qualitative methods, a multi-dimensional evaluation index system of relative poverty was constructed, and spatial autocorrelation model and geographical weighted regression model were used to analyze the measurement and spatiotemporal evolution of relative poverty in 78 counties (cities) in Shaanxi Province between 2014 and 2023. Furthermore, this study identified key influencing factors for the risk of returning to poverty and proposed targeted anti-poverty strategies. The results of this study show that the county relative poverty in Shaanxi province showed significant spatial agglomeration characteristics and obvious regional differences. Meanwhile, this study also found that factors such as education level, health conditions and industrial development had an important influence on the risk of returning to poverty. Based on this, this research puts forward policy suggestions such as strengthening education and medical investment and promoting industrial diversification development, in order to provide scientific basis and decision support for realizing the strategic goal of rural revitalization in Shaanxi Province.
Analytics revolution in pharmaceutical industry: A technical perspective
Authors: Venkata Siva Prasad Maddala
Published: February 2025

The pharmaceutical industry is experiencing a transformative revolution through the integration of advanced analytics capabilities across its value chain. This comprehensive article explores how data-driven methodologies and analytical tools are revolutionizing various aspects of pharmaceutical operations, from drug discovery to patient care. The article encompasses computational drug discovery, clinical trial optimization, manufacturing analytics, supply chain optimization, personalized medicine, sustainability analytics, and technical infrastructure requirements. The implementation of artificial intelligence, machine learning, and big data analytics has significantly improved operational efficiency, reduced costs, enhanced quality control, and accelerated drug development processes. These technological advancements have enabled more precise patient stratification, improved treatment outcomes, and fostered sustainable manufacturing practices while ensuring regulatory compliance and data security.
A comprehensive review on antimicrobial resistance in uropathogens isolated from ICU patients in the south-east Asian region
Authors: Md Rakibul Hasan  , Whitney Rogers  , Saifur Rahman  , Moryom Akter Muna  , Kanij Fatema Rabu  , Sajid Hassan
Published: February 2025

Introduction: Urinary tract infections (UTIs) are a significant concern in intensive care units (ICUs) due to the high prevalence of indwelling urinary catheters and the compromised health status of patients. The South-East Asian region faces unique challenges in managing UTIs due to varying healthcare infrastructure, antibiotic resistance patterns, and pathogen profiles. This review aims to assess the burden of antimicrobial resistance (AMR) in uropathogens isolated from ICU patients in this region.

Methods: This review was conducted as a content analysis, focusing on observational studies that reported on the prevalence and antimicrobial sensitivity of uropathogens in ICU patients in the South-East Asian region. Data were extracted from studies published between January 2020 and June 2023. The risk of bias was assessed using the tool developed by Hoy et al., and the quality of included studies was evaluated using the NIH quality assessment tool. Statistical analyses were performed using STATA 16.0.

Results: A total of 50 studies met the inclusion criteria, providing data on 50,000 ICU patients. The pooled prevalence of UTIs was 25% (95% CI: 20%-30%). Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa were the most commonly isolated uropathogens. High resistance rates were observed in Escherichia coli to ampicillin (70%) and ciprofloxacin (50%), and in Klebsiella pneumoniae to cephalosporins (60%) and carbapenems (40%). The heterogeneity among studies was moderate (I² = 60%).

Discussion: The high prevalence of UTIs and significant resistance rates underscore the urgent need for effective infection control measures and antimicrobial stewardship programs. The variability in resistance rates suggests that local factors play a significant role in the emergence and spread of AMR.

Conclusion: This review highlights the significant burden of AMR in uropathogens isolated from ICU patients in the South-East Asian region. Continuous surveillance and a multifaceted approach are essential for addressing this pressing issue.
Primary squamous cell carcinoma of the sigmoid colon revealed by acute intestinal obstruction: A case report and literature review
Authors: Ahmed  Zeroual  , Mohammed Essaid Ramraoui  , Ahmed EL Guazzar  , Mohamed Jawad  Fassi EL Fihri  , Hicham  Baba  , Mohammed  Lahkim  , Ahmed El Khader  , Rachid, El Barni
Published: February 2025

Primary squamous cell carcinoma (SCC) of the colon is an exceptional tumor. Fewer than 150 cases have been reported in the literature up to 2014. Besides its rarity, it is often associated with other digestive neoplasms. We report the case of a 54-year-old patient with primary SCC of the colon. This case allows us to discuss the anatomo-clinical and therapeutic characteristics, as well as the etiopathogenic hypotheses of this uncommon entity.
Evaluating the benefits of Ultra-High-Performance Fiber Reinforced Concrete (UHPFRC) for Rehabilitation of Dams: Insights for Potential Integration into the KDRP in Zambia
Authors: Musonda Katongo  , Pu Zhang
Published: February 2025

Ultra-high-performance fiber-reinforced concrete (UHPFRC) is a cutting-edge material in the field of cement-based engineering, offering significant advancements over traditional concrete. Its superior compressive strength along with its enhanced durability, has garnered growing interest across the globe. UHPFRC's ability to withstand aggressive conditions and its high resistance to abrasion and corrosion make it particularly suitable for applications demanding long-term performance. Experiments carried out on UHPFRC has revealed a compressive strength greater than 150MPa. The choice of fibers, their quantity, alignment, and length are crucial factors that shape the mechanical characteristics of UHPFRC. UHPFRC has gained notable notoriety as a versatile material that can be tailored to suit specific project needs as its mechanical properties can be modified to match the requirements of the intended application. Developing sustainable structures is essential for advancing Zambia's energy sector, particularly in the construction and rehabilitation of dams, with a specific focus on large-scale hydroelectric power facilities like the Kariba Dam. Because of the damage in its significant parts, such as the plunge pool and sluice gates, the Kariba Dam is now in a dangerous state that needs urgent rehabilitation. The continued operation of the Kariba Dam depends heavily on timely rehabilitation efforts to address aging infrastructure and environmental wear. Traditional concrete often exhibits limitations that require frequent repairs and high costs. UHPFRC has emerged as a promising alternative to conventional concrete due to its superior mechanical properties, durability, and reduced environmental footprint. The study compares UHPFRC with conventional concrete, highlighting the benefits and limitations of each material in dam rehabilitation. By analyzing the Kariba Dam Rehabilitation Project (KDRP), the paper explores how Ultra-High-Performance Fiber Reinforced Concrete (UHPFRC) could offer a superior alternative to conventional concrete. It discusses the material's characteristics, its advantages in terms of structural performance and longevity, and the economic and environmental implications. The study argues that while conventional concrete has been the material of choice for decades due to its availability, cost-effectiveness, and proven performance, UHPFRC offers superior durability, strength, and longevity, which could extend the lifespan of Zambia's existing dams.
The effectiveness of e-learning on academic growth: A Post-COVID-19 study on Moroccan undergraduate students
Authors: Salma Habiballah  , Mehdi Belghmi  , Latifa Belfakir
Published: February 2025

The repercussions of the COVID-19 pandemic have had a tremendous influence on education, pushing students to migrate to distance or online learning, which has prompted problems with how students perceive this new mode of learning. Hence, this paper aims to investigate students’ perceptions of online learning by assessing student engagement, learning outcomes, and student satisfaction in the context of Moroccan higher education. The study addresses the extent to which those three variables affect students’ perceptions of online education. Adopting the mixed methods approach, this study recruited 100 EFL undergraduate students from the University of Sidi Mohamed Ben Abdellah to investigate their perceptions towards online education through self-reported questionnaire responses and in-depth interview explanations. The findings showed that online learning is viewed negatively among Sidi Mohamed Ben Abdellah University students, since quantitative scores of engagements, learning outcomes, and satisfaction were low for the study’s participants. At the same time, the qualitative data revealed the causes of students’ general dissatisfaction with online learning, which stemmed from the poor quality of communication, feedback, and technical help they received.
Review on Plant Parasitic Nematode (PPN) Infections in Sugarcane Cultivation Using AI Algorithms
Authors: Viswanathan Arjunan  , Surya Prabha Deenan
Published: February 2025

Sugarcane farming plays a vital role in India's economy, society, and culture, as the country is among the top producers and users of sugarcane globally. Plant parasitic nematodes (PPNs) is a major global threat to sugarcane crops, resulting in yield reductions and financial hardship for farmers. In order to minimize crop damage and implement efficient management strategies, the early detection of nematode infestations is imperative. Artificial Intelligence (AI) presents a viable approach for the early identification, tracking, and prevention of damage caused by nematodes through the implementation of cutting-edge machine learning algorithms, remote sensing technologies, and data analytics. This review focuses on the use of AI in sugarcane crop nematode infection detection and management. By integrating AI technologies in a complementary way with conventional agricultural practices, it is feasible to enhance the productivity and resistance of sugarcane crops to nematode infections.
From branding to sales conversion: How AI-Powered CRM systems shape the customer journey for African SMEs
Authors: Justina Eweala Abubakar  , Samuel Omokhafe Yusuf  , Prosper Onagie Yusuf
Published: February 2025

This study examines the impact of AI-powered Customer Relationship Management (CRM) systems on African Small and Medium-sized Enterprises (SMEs), focusing on how these systems enhance the customer journey, improve branding, and drive sales conversions. African SMEs face significant challenges, including limited access to finances and resources, lack of expertise, political instability, corruption, and lack of government support, which hinder their ability to scale and compete effectively. The study utilizes a combination of case studies and literature reviews to explore the application of AI-driven CRM tools across various sectors such as retail, agriculture, and services. It highlights the practical implementation of CRM platforms like HubSpot, Zoho, and Salesforce Einstein in helping SMEs automate customer interactions, optimize marketing strategies, and personalize customer experiences. Findings indicate that AI-powered CRM systems significantly streamline the customer journey for African SMEs by automating key processes such as lead nurturing, customer support, and personalized marketing. These systems improve brand consistency, foster stronger customer engagement, and increase sales conversion rates. Case studies from different sectors show how SMEs successfully utilize AI tools to tailor their services to customer needs and enhance their competitive edge. In conclusion, AI-powered CRM systems provide African SMEs with an affordable, scalable solution to overcome resource constraints and improve branding and customer service. To fully leverage these benefits, SMEs should adopt accessible AI tools like SaaS CRM platforms and focus on mobile-first strategies. Future research should explore the long-term impact of AI on SME growth, the effectiveness of different AI tools in regional markets, and strategies for overcoming barriers to AI adoption, such as technological and infrastructure limitations.
Influence of the shape of the grain boundary on the I-V characteristic, power and diffusion capacity of the cylindrical grain solar cell
Authors: Modou Kara MBENGUE  , Serigne Ndiangue LEYE  , Mamadou Salif DIALLO  , Senghane MBODJI
Published: February 2025

In this study, a numerical simulation of a three-dimensional model was carried out to analyze the excess minority carrier density in the base of a bifacial polycrystalline silicon solar cell composed of cylindrical grains. The solution obtained is adapted to boundary conditions that take into account the shape of the grain boundaries. The idea of the shape of the grain boundaries was used to characterize the charge carrier density of the solar cell illuminated from both sides and to evaluate the I-V characteristic, the power and the diffusion capacity. Plots of charge carrier density, power and diffusion capacity were used to investigate the influence of grain boundary shape on the electrical parameters of the n+-p-p+ solar cell. The results indicate that the grain boundary size plays a very significant role on the production activity of the solar cell. Therefore, this study highlights the importance of production losses in the cell due to the shape of the grain boundaries.
SOSIALISASI BAHAYA RADIASI SMARTPHONE TERHADAP ANAK
Authors: Salakory Dince , Dasmasela Levina , Armila Armila , Wattimena Juan Febrian
Published: February 2025

Smartphone atau HP memancarkan radiasi Radio Frequency (RF) tingkat rendah, yang merupakan jenis radiasi elektromagnetik yang dapat diserap oleh jaringan tubuh di dekatnya. Efek kesehatan dari paparan radiasi elektromagnetik seperti dari smartphone juga bervariasi. Tujuan dilaksanakannya sosialisasi ini adalah (1) memberikan pengetahuan pada anak usia dini tentang bahaya radiasi bermain smartphone yang berlebihan serta dampak negative yang akan mereka dapatkan dan (2) memberikan solusi serta cara untuk mengurasi dampak negative radiasi smartphone. Adapun peserta kegiatan ini adalah anak-anak di daerah sekitar daerah kelurahan kudamati dari rentang 8-10 tahun yang memiliki dan aktif menggunakan smartphone. Temuan yang didapat ketika kegiatan ini diadakan adalah anak cenderung menggunakan smartphone dengan rentang waktu hampir setiap hari dan setiap saat dengan belasan jam penggunaan dalam sehari.Hasil yang didapatkan yaitu anak-anak selaku pengguna smartphone di Kelurahan Kudamati daerah Kudamati telah memahami akan pentingnya Bahaya Radiasi Smartphone pada Anak-anak.
SOSIALISASI PEMBUATAN MIE SAGU DI NEGERI SIRISORI AMALATU, SAPARUA TIMUR
Authors: Hasimin Mega Apriani
Published: February 2025

Negeri Sirisori Amalatu memiliki potensi bahan pangan lokal berupa sagu. Bahan pangan lokal ini hingga sekarang masih dikonsumsi oleh masyarakat setempat namun dalam bentuk pangan yang masih sederhana seperti papeda dan sagu lempeng. Kegiatan sosialisasi ini sangat bermanfaat bagi peserta karena mampu meningkatkan produk sagu menjadi mie untuk nilai jual yang tinggi sehingga mampu membantu dalam perekonomian pendapatan keluarga. Mie sagu memiliki karakteristik yang berbeda dengan mie yang terbuat dari terigu, berukuran lebih besar dan lebih transparan. Teksturnya juga lebih kenyal daripada mie dari terigu. Satu hal penting yang membedakan mie sagu dengan mie dari terigu adalah manfaat kesehatannya. Mie sagu tidak hanya bermanfaat untuk kesehatan saja. Bahan makanan ini juga bisa diolah menjadi berbagai macam hidangan. Selain itu, mie sagu juga lebih tahan lama dibandingkan mie dari terigu, walaupun tidak diolah menggunakan bahan pengawet. Mie sagu mengandung "resistant starch" pati yang tidak tercerna oleh saluran pencernaan manusia. Kadar Resistant starch dalam mie sagu bahkan 3-4 kali lebih banyak dibandingkan kandungan resistant starch dalam mie yang dibuat dari tepung terigu. Resistant starch ini bekerja sebagai prebiotik dan menurunkan indeks glikemik mie sagu, sehingga konsumsi mie sagu tidak akan meningkatkan kadar glukosa dalam darah dengan cepat. Dengan kata lain, mie sagu cocok dikonsumsi oleh penderita diabetes melitus. Selain itu, manfaat lain dari mie sagu adalah mencegah sembelit, melancarkan pencernaan, dan mencegah kanker usus, meningkatkan kesehatan tulang dan sendi, dan mencegah darah tinggi. Karena kandungan karbohidratnya yang tinggi, sagu juga merupakan sumber energi yang baik. Itulah sebabnya mie sagu terasa mengenyangkan dan sering dikonsumsi sebagai sajian saat sarapan.
SOSIALISASI TATA CARA TEKNIK SAMBUNG PUCUK (GRAFTING) PADA TANAMAN MANGGA (MANGIFERA)
Authors: Tallaut Mario Abraham
Published: February 2025

Program Kuliah Kerja Nyata (KKN) merupakan salah satu proses pembelajaran serta bentuk pengabdian mahasiswa kepada masyarakat banyak dan secara langsung mengidentifikasi serta menangani masalah-masalah yang sedang di hadapi masyarakat di daerah tertentu. Pemberdayaan teknik sambung pucuk (grafting) pada tanaman mangga (Mangifera) dilaksanakan pada tanggal 20, November 2023 di Desa Passo, Kec. Baguala, Kota Ambon. kegiatan ini bertujuan untuk memberikan pengetahuan sekaligus tata cara melakukan teknik sambung pucuk yang baik dan benar, guna menjadi solusi dari masalah pada budidaya tanaman rambutan. Metode yang digunakan adalah metode demplot (Demonstrasi Plot) yaitu salah satu metode penyuluhan dengan cara membuat lahan percontohan sehingga petani sebagai pelaku utama bisa melihat dan membuktikan dari objek yang didemonstrasikan. Hasil dari pemberdayaan teknik sambung pucuk pada tanaman rambutan adalah para masyrakat mengetahui teknik sambung pucuk (grafting) yang baik dan benar dan bisa merealisasikan langsung pada tanaman budidaya mereka sendiri.
SOSIALISASI PEMBUATAN PESTISIDA NABATI DAUN PEPAYA DI PT.NISAINA GROUP KEBUN WILAYA II /PT MITRA USAHA MAJU BERSAMA DESA LATEA
Authors: Reniwuryaan Sirnawati
Published: February 2025

Pencemaran lingkungan yang dilakukan oleh residu pestisida sintesis semakin bertambah buruk terhadap lingkunagan. Pembuatan pestisida nabati merupakan sosialisasi alternative yang dapat dilakuakan guna mengurangai dampak pencemaran. Daun pepaya (carica pepaya) yang diketahui menggunalan enzyme papain sangant berpotensi dikembangkan sebagai bahan baku pembuatan pestisida nabati. Penelitian ini bertujuan untuk mendaptkan metode pembuatan pestiseda nabati dari daun pepaya yang efektif. Penelitian dilakukan dalam tiga tahap yaitu pembuatan pestisida tanpa modifikasi,, pembuatan pestisida termodifikasi minyak tanah dan deterjen dan uji kinerja terhadap hama.
PROSES PENGELOLAAN HASIL HUTAN BUKAN KAYU (HHBK) GULA AREN DI DESA ETI KECAMATAN SERAM BARAT KABUPATEN SERAM BAGIAN BARAT
Authors: Maslebu Odri Tara
Published: February 2025

Hasil Hutan Bukan Kayu (HHBK) berperan penting dalam ekosistem hutan dan kehidupan manusia. HHBK telah digunakan oleh masyarakat sekitar hutan secara langsung maupun tidak langsung. HHBK memiliki nilai ekonomi yang penting dan dapat memenuhi kebutuhan masyarakat dalam hal pangan, papan, dan keperluan ritual. Beberapa jenis HHBK yang telah dimanfaatkan dan dikomersialkan antara lain cendana, gaharu, sagu, rotan, aren, sukun, bambu, sutera alam, jernang, kemenyan, kayu putih, aneka tanaman obat, minyak atsiri, dan madu. Salah satu HHBK yang memiliki nilai ekonomi tinggi dan menjadi sumber pendapatan masyarakat pedesaan adalah Arenga pinnata atau yang dikenal sebagai enau atau aren. Aren (Arenga pinnata Merr.) adalah pohon serbaguna yang telah lama dikenal menghasilkan bahan-bahan industri. Tumbuhan aren menghasilkan buah, nira, dan pati atau tepung di dalam batangnya. Semua hasil produksi aren ini memiliki nilai ekonomi dan dapat dimanfaatkan, termasuk akar, batang, buah, tandan bunga, dan ijuk. Di Maluku, banyak tumbuh pohon aren, dan masyarakat di pedesaan memanfaatkannya untuk konsumsi dan produksi. Salah satu bagian aren yang digunakan adalah tangkai bunganya yang menghasilkan air nira atau sageru. Air nira ini dapat diolah menjadi sageru, cuka, gula aren, dan sopi, yang menjadi sumber pendapatan masyarakat. Di desa Eti, kecamatan Seram Barat, kabupaten Seram Bagian Barat, mayoritas penduduknya adalah petani. Salah satu komoditas utama yang dimanfaatkan adalah air nira dari pohon aren untuk dijadikan sopi, gula aren, dan adonan kue. Meskipun gula aren juga memiliki nilai ekonomi, produksinya masih terbatas di kalangan masyarakat. Oleh karena itu, pada saat menjelang hari-hari besar seperti Natal dan Paskah, baru diproduksi dalam jumlah yang lebih banyak. rogram KKN Tematik Individu memiliki bertujuan untuk mengembangkan ketrampilan dan pengetahuan mahasiswa dalam bidang yang ditekuni, dan juga memberikan pengalaman belajar yang nyata kepada mahasiswa. Melalui program ini, mahasiswa dapat belajar dan bekerja dalam masyarakat untuk menerapkan dan mengembangkan ilmu dan pengetahuan di luar kampus. Program ini juga dapat meningkatkan keterampilan mahasiswa dalam memecahkan masalah yang ada di masyarakat serta memberikan informasi terkait pengelolaan HHBK Gula Aren dalam upaya meningkatkan perekonomian masyarakat desa Eti.
PEMETAAN POTENSI SUMBER MATA AIR DI DESA MEGERI
Authors: Rante Queen Athalia Deborah
Published: February 2025

Desa Megeri merupakan salah satu desa yang berada di Kecamatan Kradenan Kabupaten Blora, Provinsi Jawa Tengah, berbatasan langsung dengan Desa Selopuro Kecamatan Pitu Kabupaten  Ngawi, Jawa Timur. Desa Megeri terdiri dari 3 Dusun yaitu Dusun Megeri, Dusun Setren dan Dusun Sembungan. Permasalahan yang ada di Desa Megeri belum ada pemetaan tentang  potensi sumber air pada desa tersebut. Untuk itu kegiatan pengabdian kepada masyarkat  dilaksanakan dalam bentuk sosialisasi dengan tujuan menambah pengetahuan lebih tentang  pemetaan potensi sumber mata air bagi masyarakat. Metode pengabdian yang  dilakukan yaitu  sosialisasi berupa pemaparan hasil pemetaan potensi sumber mata air yang diakhiri dengan sesi tanya jawab. Materi yang disampaikan dalam sosialisasi adalah pengertian peta hingga cara  pembuatan peta sederhana yang didalamnya terdapat titik-titik sumber mata air dan juga  manfaat dari pembuatan peta. Partisipan berantusias dalam kegiatan sosialisasi dan sesi tanya  jawab