bluuebunny/crossref_metadata_2025 huggingface dataset:
Investigating the impact of psychedelic drugs on social cognition defects: A scoping review protocol
Authors: Smith Sarah Ann , Smith Shaina , Dennett Liz , Zhang Yanbo
Published: July 2024

Background

Impairments in social cognition are known to be a key factor in several psychiatric and neurodevelopmental disorders. Interest in psychedelic drugs has increased in recent years, with significant research identifying psychedelic and hallucinogenic drugs as modulators of social cognition. However, more research is necessary before psychedelics are implemented in clinical settings as treatments for social cognition defects. Therefore, this study describes a scoping review protocol which will be used to analyze the body of literature on psychedelic drugs as modulators of social cognition in patients with psychiatric and neurodevelopmental disorders.

Methods

This scoping review protocol was developed using the JBI Scoping Review Methodology Group’s description of how to conduct a scoping review. The guidelines identified by this group as well as a search strategy developed with the assistance of a research librarian will be applied to a search of several peer-reviewed journals, including MEDLINE (Ovid), PsycINFO, EMBASE (Elsevier), and Scopus (Elsevier). Each study extracted will be screened in a two-step screening process, including a title and abstract screen, and a full-text screen. One independent individual will complete both steps of the screening, and a second independent individual will review the completed screening.

Discussion

An understanding of the current literature on psychedelic drugs as modulators of social cognition will provide insight into what is presently known on the subject, and any gaps in the literature that can be addressed in future studies. The knowledge gained from this scoping review could lead to a new treatment for social cognition defects in clinical populations.
The relationship of milk expression pattern and lactation outcomes after very premature birth: A cohort study
Authors: Levene Ilana , Fewtrell Mary , Quigley Maria A , O’Brien Frances
Published: July 2024

Introduction

Mothers of very premature infants often have difficulties expressing breastmilk, which can cause distress and potential negative impact on infant health. Clinical recommendations on breastmilk expression are extrapolated from term infants’ breastfeeding patterns. This study’s objective was to analyse the association of expressing pattern with lactation outcomes after very premature birth.

Methods

132 participants were recruited after birth between 23+0 and 31+6 weeks’ gestation. Participants recorded the milk expressed in several 24-hour periods in the three weeks after birth.

Results

Expressing frequency was positively associated with 24-hour milk yield, with an adjusted 30.5g increase per expressing session on day four (95% CI 15.7 to 45.3) and 94.4g on day 21 (95% CI 62.7 to 126.2). Expressing ≥8 times per day was associated with higher adjusted milk yield than expressing <6 times (on day four, 146.8g, 95% CI 47.4 to 246.1), but not in comparison to expressing 6–7 times (on day four, 82.1g, 95% CI –25.9 to 190.1). Participants with six months or more prior breastmilk feeding experience had a higher adjusted milk yield than others (on day four, 204.3g, 95% CI 125.2 to 283.3). Night-time (2300–0700 hours) expressing sessions were not associated with increased milk yield after adjustment for time since the prior session. On average, participants who had a longest gap between expressions of less than six hours achieved the UK target of 750g breastmilk, whereas those with a longer gap did not.

Conclusion

Expressing frequency was an important determinant of milk yield. Clinical recommendations to express ≥8 times per day were supported but for some, 6–7 times was sufficient. This was particularly likely for those with six months or more of prior breastmilk feeding experience. A need to express during the night-time hours appeared to be related to minimising the gap between expressions rather than an inherent value of night-time expression.
Increased serum caspase-1 in adult-onset Still’s disease
Authors: Matsumoto Haruki , Yoshida Shuhei , Koga Tomohiro , Fujita Yuya , Sumichika Yuya , Saito Kenji , Temmoku Jumpei , Asano Tomoyuki , Sato Shuzo , Mizokami Masashi , Sugiyama Masaya , Migita Kiyoshi
Published: July 2024

Background

Caspase-1 is a crucial component in the inflammasome activation cascade. This study evaluated the potential of serum caspase-1 level as an inflammatory biomarker in patients with adult-onset Still’s disease (AOSD).

Methods

The study included 51 consecutive patients diagnosed with AOSD based on the Yamaguchi criteria, 66 patients with rheumatoid arthritis (RA) as disease control, and 36 healthy controls (HCs). Serum caspase-1 concentrations were measured using enzyme-linked immunosorbent assay. The serum 69 cytokine levels were analyzed using a multisuspension cytokine array in patients with AOSD, and a cluster analysis of each cytokine was performed to determine specific molecular networks.

Results

Patients with AOSD had significantly increased serum caspase-1 levels versus patients with RA (p < 0.001) and HCs (p < 0.001). Additionally, serum caspase-1 demonstrated significant positive correlations with AOSD disease activity score (Pouchot score, r = 0.59, p < 0.001) and serum ferritin (r = 0.54, p < 0.001). Furthermore, among patients with AOSD, significant correlations existed between serum caspase-1 and inflammatory cytokines, including interleukin-18. Immunoblot analysis detected the cleaved form of caspase-1 (p20) in the serum of untreated patients with AOSD, not in those from patients with inactive AOSD receiving immunosuppressive treatments.

Conclusions

Caspase-1 is a useful biomarker for AOSD diagnosis and monitoring. Caspase-1 activation could be correlated with the inflammatory component of AOSD, specifically through proinflammatory cytokine induction via inflammasome activation cascades.
Dipeptidyl peptidase 4 inhibitor sitagliptin decreases myocardial fibrosis and modulates myocardial insulin signaling in a swine model of chronic myocardial ischemia
Authors: Harris Dwight D. , Sabe Sharif A. , Broadwin Mark , Stone Chris , Bellam Krishna , Malhotra Akshay , Abid M. Ruhul , Sellke Frank W.
Published: July 2024

Objective

Although both clinical data and animal models suggest cardiovascular benefits following administration of Dipeptidyl Peptidase 4 (DPP-4) inhibitors, the underlying mechanisms remain unclear. We therefore sought to evaluate the effect of the DPP-4 inhibitor sitagliptin on myocardial fibrosis, and insulin signaling in chronic myocardial ischemia using a swine model. An ameroid constrictor placement on the left coronary circumflex artery of thirteen Yorkshire swine to model chronic myocardial ischemia. After two weeks of recovery, swine were assigned to one of two groups: control (CON, n = 8), or sitagliptin 100mg daily (SIT, n = 5). After 5 weeks of treatment, the swine underwent terminal harvest with collection of myocardial tissue. Fibrosis was quantified using Masson’s trichrome. Protein expression was quantified by Immunoblotting. Trichrome stain demonstrated a significant decrease in perivascular and interstitial fibrosis in the SIT group relative to CON (all p<0.05). Immunoblot showed a reduction in Jak2, the pSTAT3 to STAT 3 Ratio, pSMAD 2/3, and SMAD 2/3, and an increase in STAT 3 in the SIT group relative to CON (all p<0.05). SIT treatment was associated with increased expression of insulin receptor one and decreased expression of makers for insulin resistance, including phospho-PKC- alpha, RBP-4, SIRT1, and PI3K (p<0.05). Sitagliptin results in a reduction in perivascular and interstitial fibrosis and increased insulin sensitivity in chronically ischemic swine myocardium. This likely contributes to the improved cardiovascular outcomes seen with DPP-4 inhibitors.
Structural modelling and preventive strategy targeting of WSSV hub proteins to combat viral infection in shrimp Penaeus monodon
Authors: Panrat Tanate , Phongdara Amornrat , Wuthisathid Kitti , Meemetta Watcharachai , Phiwsaiya Kornsunee , Vanichviriyakit Rapeepun , Senapin Saengchan , Sangsuriya Pakkakul
Published: July 2024

White spot syndrome virus (WSSV) presents a considerable peril to the aquaculture sector, leading to notable financial consequences on a global scale. Previous studies have identified hub proteins, including WSSV051 and WSSV517, as essential binding elements in the protein interaction network of WSSV. This work further investigates the functional structures and potential applications of WSSV hub complexes in managing WSSV infection. Using computational methodologies, we have successfully generated comprehensive three-dimensional (3D) representations of hub proteins along with their three mutual binding counterparts, elucidating crucial interaction locations. The results of our study indicate that the WSSV051 hub protein demonstrates higher binding energy than WSSV517. Moreover, a unique motif, denoted as "S-S-x(5)-S-x(2)-P," was discovered among the binding proteins. This pattern perhaps contributes to the detection of partners by the hub proteins of WSSV. An antiviral strategy targeting WSSV hub proteins was demonstrated through the oral administration of dual hub double-stranded RNAs to the black tiger shrimp, Penaeus monodon, followed by a challenge assay. The findings demonstrate a decrease in shrimp mortality and a cessation of WSSV multiplication. In conclusion, our research unveils the structural features and dynamic interactions of hub complexes, shedding light on their significance in the WSSV protein network. This highlights the potential of hub protein-based interventions to mitigate the impact of WSSV infection in aquaculture.
Understanding early HIV-1 rebound dynamics following antiretroviral therapy interruption: The importance of effector cell expansion
Authors: Phan Tin , Conway Jessica M. , Pagane Nicole , Kreig Jasmine , Sambaturu Narmada , Iyaniwura Sarafa , Li Jonathan Z. , Ribeiro Ruy M. , Ke Ruian , Perelson Alan S.
Published: July 2024

Most people living with HIV-1 experience rapid viral rebound once antiretroviral therapy is interrupted; however, a small fraction remain in viral remission for an extended duration. Understanding the factors that determine whether viral rebound is likely after treatment interruption can enable the development of optimal treatment regimens and therapeutic interventions to potentially achieve a functional cure for HIV-1. We built upon the theoretical framework proposed by Conway and Perelson to construct dynamic models of virus-immune interactions to study factors that influence viral rebound dynamics. We evaluated these models using viral load data from 24 individuals following antiretroviral therapy interruption. The best-performing model accurately captures the heterogeneity of viral dynamics and highlights the importance of the effector cell expansion rate. Our results show that post-treatment controllers and non-controllers can be distinguished based on the effector cell expansion rate in our models. Furthermore, these results demonstrate the potential of using dynamic models incorporating an effector cell response to understand early viral rebound dynamics post-antiretroviral therapy interruption.
A rede de atenção à saúde, a prática interprofissional e o capitalismo contemporâneo
Authors: Gois Rosimeire
Published: July 2024

Este ensaio tem como objetivo geral refletir sobre a importância da análise de conjuntura ao realizar uma pesquisa, considerando a relação entre Estado e capital na crise contemporânea. Entretanto, há também a necessidade de realizar a análise considerando a conjuntura capitalista moderna a qual a rede de atenção está exposta, considerado o capitalismo contemporâneo, gerencialismo na gestão pública em saúde e a interprofissionalidade na rede de atenção à saúde. Desde a reforma sanitária Brasileira, muito se ouve falar sobre a Rede de Atenção à Saúde – RAS, Sistema Único de Saúde – SUS e interprofissionalidade. Mas, pouco se falar sobre a crise do capitalismo e a quais os impactos dessa crise na saúde pública. O ensaio deriva de pesquisa de doutorado. O objetivo é analisar ações colaborativas no trabalho em equipe. Os resultados esperados descrever a intencionalidade de ações colaborativas conjunta e contribuir para a ampliação políticas públicas de fortalecimento ao SUS.
O pensamento da epidemiologia crítica de Jaime Breilh e a economia política da saúde de Michael Harvey
Authors: Macedo Aline do Nascimento , Fernandes Beatriz Campanerut , Silva Cleide Bonifácio da , Rigoni Helena Hoffmann , Aquino Luz Graciela Wild , Olivares Miguel Armando Zúñiga , Amaral Sergio Henrique do
Published: July 2024

Neste ensaio crítico, realizou-se uma reflexão teórica sobre a relação entre o sistema capitalista e as iniquidades sociais e em saúde, através de um dos estudos sobre economia política da saúde de Michael Harvey à luz do pensamento crítico de Jaime Breilh, autor destacado da epidemiologia crítica originada do movimento latino-americano da medicina social/saúde coletiva. O texto está estruturado em três partes. A primeira descreve uma breve biografia intelectual e político-institucional de Michael Harvey e Jaime Breilh a fim de situá-los historicamente. A segunda descreve e explica o pensamento de Michael Harvey ao analisar a economia política da saúde. A terceira discute o valor do pensamento da epidemiologia crítica de Jaime Breilh. Por fim, compreende-se a conjunção de ideias desses autores na discussão das iniquidades sociais e em saúde reproduzidas pelo sistema capitalista, permitindo avançar, desde uma perspectiva histórico-crítico, na análise ampla e aprofundada da realidade social e sanitária.
Wychowawczy, edukacyjny i społeczny wymiar wileńskich cechów doby wczesnonowożytnej. Towarzysz w służbie mistrza i cechu
Authors: Manyś Bernadetta
Published: July 2024

In the following paper I would like to analyze educational, social and upbringing related dimensions of Vilnius guilds, employing apprentices. They not only worked but, participating in manufacturing of goods, they also prepared themselves for the profession. In this article, I take a look at the functioning of this group in the structures of guilds and workshops run by Vilnius craftsmen. The question arises what was expected of them as members of craft workshops and guilds. How the companions’ dependence on the master, for whom they worked, changed. In addition, there is an issue of the role of practice – the journey that had to be made in the case of some professions and the skills acquired in the process. The following research does not have an ambition of being a holistic study of the issue; it is a revision and a supplement to Józef Morzy’s research where he partly analyzed craft guilds in Vilnius, in terms of essential work skills. In order to explain these issues, the statutes of the craft guilds were analyzed in Vilnius, one of the biggest cities of the Polish–Lithuanian Commonwealth, in the early modern period.
Szkolne przygotowanie uczniów staropolskich kolegiów jezuickich do służby politycznej
Authors: Nowicki Michał
Published: July 2024

The primary purpose of this article is to show the opportunities offered by old-Polish Jesuit education in preparing young people for political service, from the historical and pedagogical perspective. Due to the scarcity of fundamental studies on everyday school practice in Jesuit colleges of the First Polish Republic, the text will analyze selected source texts, possibly from various periods and school centers. Of course, the framework of the article does not allow for thorough comparative studies on such an extensive issue that deserves a monographic study. To avoid generalities, the paper will focus on showing specific content standards in the Jesuits school circle. The source material on everyday school life in the old-Polish period is abundant and still unsatisfactorily used, to mention school notebooks and lecture scripts, school panegyric literature, and programs of theater plays (these enjoy the greatest interest).
Edukacja bocznych linii rodu Radziwiłłów w XVIII wieku. Wyznacznik statusu społecznego czy szansa na awans?
Authors: Mariani Andrea
Published: July 2024

The paper analyses the education of the members of three collateral lines of the Radziwiłł family (Kleck, Szydłowiec and Berdyczów) between the late 17th century and 1773, the year of the suppression of the Society of Jesus. The author has resorted to various archival sources, particularly private letters and diaries. The decline in social prestige of these family lines determined the way in which their members were educated. While all the members of the first generation studied in various Jesuit colleges and later undertook the grand tour, later on most Radziwiłłs were educated under the supervision of their more powerful relatives from Nieśwież. Nevertheless, they received careful education, often in Jesuit or Piarist colleges for noblemen. Command of modern languages, history and geography favoured their political career during the crisis of the Nieśwież branch in the 1760s. After reconstructing the early life of various members of the Radziwiłł family, the author analyses the criteria that determined the choice of various schools.
W domu i na pensji – dziewczęce zapiski i kobiece wspomnienia o edukacji z końca XVIII wieku
Authors: Żołądź-Strzelczyk Dorota , Kowalczyk Małgorzata Ewa
Published: July 2024

Women’s opportunities to acquire knowledge and skills in the 18th century still differed significantly from men’s. Girls had fewer choices: education at home, or at a finishing school. It was mainly convent education, over time giving way to secular education. This article attempts to show education from the perspective of women, their memories recorded in diaries. Two of them were selected for this purpose. The author of the first, Wirydianna Fiszerowa, née Radolińska, described and evaluated her home education retrospectively. She showed a lack of consistency and a thoughtful approach, frequent changes of teachers, whom she sometimes assessed in a decidedly negative way, the teaching and upbringing methods they used. The other girl, Apolonia Helena Massalska, while studying at a convent finishing school, wrote down her diary on a regular basis, showing the life of her peers, her relations with the teachers and their educational methods. In the first case, the author could distance herself after several decades and life experience; she included a reflection on the scope and method of providing education. This second diarist, inevitably deprived of distance, basically limited herself to describing life and teaching at the finishing school.
An Overview of the Groundwater Situation in Namkhana Block, Sundarban Biosphere Reserve, India, from the Pinnacle of a Propagating Delta Front: A Post-Monsoonal Survey
Authors: Das Uddipan ,   Jadavpur University, Chaudhuri Susanta , Halder Bijay , Dutta Poulomi ,   Jadavpur University,   Vidyasagar University,   Jadavpur University
Published: July 2024

This study is a real-time hydrogeological investigation to appraise the groundwater scenario and spatial variations of its major physicochemical parameters at the southernmost apical fringe of the Indian Sundarban Biosphere Reserve area in mesoscale during the recent post-monsoon season (PoM). The study was based on the acquisition and analysis of primary field data collected from the southernmost apex of the river Ganga-Brahmaputra-Meghna delta and restricted to the Namkhana Development Block of South 24 Parganas district, West Bengal, India. Twenty-two groundwater samples were collected from bore wells post-monsoon (October 2022). Measurements of major physical parameters were done in situ. Geospatial contour maps representing variations of influencing parameters were prepared. The drinking and irrigation suitability of the water was validated by existing standard equations and plots. Chemical analyses were done to evaluate its hydrochemistry and suitability for drinking and agriculture. Obtained results primarily revealed that TDS and pH are at marginal ranges with significantly alarming concentrations for some major contributing ions, chiefly bicarbonates, and sodium. The overall suitability of groundwater for agriculture, drinking, and domestic purposes differs from acceptable limits. Indiscriminate groundwater exploitation from deeper aquifers for agriculture seemed to be the prime factor responsible for this situation.
Agoranomische Urkunden aus Philadelpheia (P.Freib. 78 und 79)
Authors: Gerardin François , Neitmann Stephan , Weisser-Gericke Lucas
Published: July 2024

The texts published here for the first time are documents copied at the branch of the agoranomos’s office in Philadelphia in the first half of the second century BCE. P.Freib. 78, on the one hand, records a conciliation before the chrematistai, which comprised the official recording of the mutual concessions made by the parties as well as a memorandum to the judges. The attestation of an Atargateion, a private sanctuary dedicated to the “Syrian goddess”, provides a link to another papyrus of the Freiburg collection (P.Freib. 42) and suggests Philadelphia as the likely provenance of the piece. P.Freib. 79a‒c, on the other hand, were written in the same hand as P.Freib. III 32-33 and a recently edited papyrus from the collection in Giessen, which provides a secure paleographical link with the agoranomic material from Philadelphia.
A double clad ASE Re-injected hybrid TDFA and HDFA amplifier with ±1.44 dB GF
Authors: Bhandari Vijaya , Trivedi Neelu
Published: July 2024

Current developments in wireless communications accentuate the exigency of high gain, low noise figure (NF) and minimum gain fluctuations (GF) based optical amplifier in 1.9–2.15 μm eye safe wavelength band. Hybrid thulium (Tm) doped fiber amplifier (TDFA) and holmium (Ho) doped fiber amplifier (HDFA) are the perfect candidates to extend the bandwidth towards 2 μm long wavelengths. In this work, amplifier spontaneous emission (ASE) re-injected double clad TDFA-HDFA hybrid amplifier using Fiber bragg gratings (FBGs) is presented for the amplification of 64 wavelength division multiplexed (WDM) channels covering 63 nm wavelength window. Further, performance of proposed amplifier with and without ASE reinjection is evaluated in terms of Gain, NF, GF and optical signal to noise ratio (OSNR). Effects of single and double clad on the Gain are studied and optimization of Tm and Ho doped fiber length, pump powers, and input power has also been accomplished. The GF as low as ±1.44 dB, Gain >28 dB, NF < 5.08 dB, output power 4.2 W are achieved in ASE re-injected configuration using 785 nm pump at 55 dBm in TDFA and 1,900 nm pump at 20 dBm in HDFA. It is noticed that double clad and ASE reinjection in TDFA and HDFA offer better GF.
Comparative morphology of the cruciate ligaments: A radiological study
Authors: Gan Xin , Chen Xin , Zeng Yunqian , Li Mengwei , Nie Mingbo , Kang Hao
Published: July 2024

Background

The anterior cruciate ligament (ACL) and posterior cruciate ligament (PCL) are important structures to maintain knee stability. The present study aimed to further enrich understandings of the morphology of the cruciate ligaments and explore the relationship between the diameter of ACL and PCL.

Method

This study collected valid MRI samples of 50 male and 50 female normal right knee joints and measured the diameter of each point of the ACL and PCL through the 3D Slicer.

Results

The diameter of the ACL in the sagittal MRI of the normal right knee joint was significantly different from the diameter of each point of the PCL. The average diameter of each point of the ACL was larger than the diameter of the corresponding point of the PCL. Males and females had statistical differences in their PCL origin point, PCL midpoint, ACL origin point, ACL midpoint, and ACL insertion point diameters under sagittal MRI examination. The average diameter of males was greater than the average diameter of females at the above corresponding sites. In sagittal MRI scans of the normal right knee joint, we observed that only the origin point of the PCL exhibited a moderate correlation with the midpoint and insertion point of the ACL in terms of their respective diameters.

Conclusion

The correlation between diameters of normal ACL and PCL in knee joint MRI was moderate and may help clinicians determine appropriate graft for cruciate ligament reconstruction surgery quickly for severe cruciate ligament injuries.
Meinen, Deuten, Verstehen
Authors: Rieger Florian
Published: July 2024

Meaning, Interpreting, Understanding

In his Kritik der verstehenden Vernunft (2018), Vittorio Hösle attempts to develop a comprehensive foundation for the so-called Geisteswissenschaften (humanities). The basis for this foundational work is a conception of understanding that ties all understanding to the interpretative grasp of what we and others mean by the use of certain symbols or linguistic expressions. The present essay argues that this makes Hösle’s approach vulnerable to a particular form of skepticism, as it is expounded by Saul Kripke in his Wittgenstein on Rules and Private Language (1982). The first part of the essay outlines this skeptical challenge and its implications for Hösle’s conception of understanding. The second part advances the argument that this conception's vulnerability to skepticism undermines its viability as a foundation for the humanities. Instead, it invites the kind of skepticism described in Kripke’s challenge, where understanding itself seems to be impossible. The essay concludes with some tentative suggestions for an alternative conception of understanding that not only avoids this skepticism altogether but also makes room for a way of thinking about the mental that is of independent interest.
Impact of Leg Strength on the Force Produced During a Cross-Punch in Highly Trained Amateur Boxers
Authors: Satkunskiene Danguole , Bruzas Vidas , Mickevicius Mantas , Snieckus Audrius , Kamandulis Sigitas
Published: July 2024

Satkunskiene, D, Bruzas, V, Mantas, M, Snieckus, A, and Kamandulis, S. Impact of leg strength on the force produced during a cross-punch in highly trained amateur boxers leg strength impact on cross-punch force. J Strength Cond Res 38(10): 1739–1744, 2024—The purpose of this study was to determine the impact of leg strength on force generation during the execution of a cross-punch by highly trained amateur boxers. This study involved 12 male, amateur boxers with a body mass range of 64.5–112.2 kg and a mean of 89.2 ± 17.0 kg. This study used an isokinetic dynamometer to measure the peak torque of the knee extensor and flexor muscles at 60°/s. The force plate was used to collect three-dimensional ground reaction forces (GRF), moments (GRM), and the center of pressure (COP) during a maximal cross-punch. The Kiktest-100 system was used to determine the force of the punch, while the Hykso punch tracker accelerometer measured the maximum fist velocity. This study revealed a positive correlation between knee extensor strength and GRFz, GRFy, and COPy during punch performance. In addition, the GRMz gradient and GRMz impulse during the execution phase have a significant positive effect on cross-punch force. In conclusion, the force of a straight punch in highly trained, amateur boxers is related to a greater angular velocity about the vertical axis during body rotation.
A LITERATURA NA EDUCAÇÃO INFANTIL: CRITÉRIOS DE SELEÇÃO E POSSIBILIDADES DE INTERVENÇÃO
Authors: Batista dos Santos Karoline , Irie Saito Heloisa Toshie
Published: July 2024

O presente artigo apresenta alguns resultados obtidos em uma pesquisa bibliográfica desenvolvida no programa de iniciação científica (PIC) de uma universidade pública no estado do Paraná que investigou como a leitura deve ser trabalhada na Educação Infantil, tendo como objeto de análise a Coleção “Leitura e Escrita na Educação Infantil” do Ministério de Educação (MEC). Objetiva discutir o papel da literatura nos espaços da Educação Infantil, bem como apresentar critérios para seleção de obras literárias e algumas possibilidades de intervenção com os livros junto as crianças. Destaca-se, primeiramente, o papel da literatura como objeto para promoção do desenvolvimento infantil em meio as práticas de leitura, tendo o planejamento como peça chave para um trabalho profícuo. Subsidiados em Paiva (2016), evidencia-se que os critérios de seleção da literatura infantil relacionam-se com a qualidade textual, a qualidade temática e a qualidade gráfica das obras elencadas para práticas com as crianças pequenas. Por fim, apresenta-se três formas de se trabalhar com a literatura na educação infantil: a contação de histórias, a leitura compartilhada e a leitura livre. Conclui-se que as atividades elencadas devem ser desenvolvidas nas instituições de educação infantil de maneira sistematizada, pois promovem o desenvolvimento das funções psicológicas superiores das crianças e a imersão delas no universo da literatura, bem como possibilitam a análise da prática docente.
SIĞIR KARKASLARINDAN İZOLE EDİLEN PSEUDOMONAS AERUGINOSA SUŞLARININ BİYOFİLM OLUŞTURMA ÖZELLİKLERİ İLE QUORUM SENSING VE MAJOR KARBAPENEMAZ GENLERİNİN ARAŞTIRILMASI
Authors: Uyanık Tolga , Bölükbaş Ayşegül , Gücükoğlu Ali , Çadırcı Özgür , Sezener Merve Gizem
Published: July 2024

Bu çalışma mezbahalardaki sığır karkaslarından izole edilen ve fenotipik olarak karbapenem direnci gösteren P. aeruginosa suşlarının biyofilm oluşturma kapasitelerini kalitatif ve kantitatif yöntemlerle araştırmak, karbapenem direncinden sorumlu major karbapenemaz ve ayrıca quorum sensing (lasI, lasR, rhlI ve rhlR) genlerinin varlığı belirlemek amacıyla gerçekleştirilmiştir. Çalışmada her biri farklı bir sığır karkas yüzeyinden izole edilen ve moleküler yöntemlerle doğrulanmış 13 P. aeruginosa suşu materyal olarak kullanılmıştır. Çalışmada tüm P. aeruginosa suşlarının test edilen karbapenemlerden en az birine karşı dirençli olduğu belirlenmiştir. Karbapenemaz genleri (blaKPC, blaOXA-48, blaNDM, blaVIM ve blaIMP) hiçbir izolatta tespit edilememiştir. Karbapenem direnci gösteren tüm izolatların kantitatif olarak güçlü biyofilm üreticisi olduğu saptanmıştır. PCR analizleri doğrultusunda analiz edilen 13 izolattan 12’sinin (%92.3) lasI, lasR, rhlI ve rhlR genlerinin tümünü içerdiği tespit edilmiştir. Bir izolatın (%7.69) sadece lasR ve rhlR genlerini içerdiği belirlenmiştir. Yapılan bu çalışma ile hayvansal orjinli P. aeruginosa suşlarında karbapenem direncinin ve biyofilm üretiminin birbirleriyle ilişki içerisinde olduğu belirlenmiştir. Halk sağlığının korunması açısından çiğ etlerden kaynaklanabilecek kontaminasyona karşı dikkatli olunması tavsiye edilmektedir.
Las comunidades judías en la Lombardía española
Authors: Sánchez Casado Ana
Published: July 2024

Este artículo propone el estudio de las comunidades judías asentadas en el Estado de Milán durante los siglos XVI y XVII, a partir de una revisión bibliográfica. El objetivo principal es el de realizar una visión general sobre la presencia de estas comunidades durante la Lombardía española, mediante el análisis y comparación de los estudios previos, y prestando particular atención al reinado de Carlos II, con el fin de estudiar los diferentes agentes que afectaron a las expulsiones de 1591 y de 1690.
Aerosol measuring complex
Authors: ВАЛИУЛИН С.В. , ОНИЩУК А.А. , БАКЛАНОВ А.М. , КАРАСЕВ В.В. , ДУЛЬЦЕВА Г.Г.
Published: July 2024

Измерительное оборудование, способное в режиме реального времени определять характеристики частиц в газовой фазе, необходимо при проведении широкого спектра исследований, включая изучение влияния антропогенных загрязнений на климатические изменения и здоровье человека, а также при разработке новых способов доставки лекарственных средств и синтезе нанокомпозитных материалов. Представлен разработанный и созданный в ИХКГ СО РАН измерительный комплекс, включающий диффузионный аэрозольный спектрометр, оптический аэрозольный спектрометр и измеритель массовой концентрации аэрозоля. Проведены лабораторные испытания приборов измерительного комплекса с использованием стандартных тестовых систем. Cопоставление показало хорошее согласие измеренных размеров частиц с данными, полученными независимыми методами (просвечивающая электронная микроскопия, измерение скорости седиментации частиц). Приборы комплекса позволяют измерять концентрацию и размер аэрозольных частиц в широком диапазоне значений с представлением результатов в реальном времени. Измерительный комплекс может быть использован в лабораторных и полевых исследованиях в области химии, физики и медицины, а также на станциях мониторинга состояния воздуха окружающей среды.

The measurement complex including diffusion aerosol spectrometer, optical aerosol spectrometer, and aerosol mass concentration meter has been developed and manufactured at the Institute of Chemical Kinetics and Combustion SB RAS. Laboratory tests of the instruments included in the measurement complex were carried out using standard test systems. Comparison of measured particle size values with the data obtained by independent methods (transmission electron microscopy and measurement of particle sedimentation velocity) revealed their good agreement. It is demonstrated that the measuring complex is suitable for determining concentrations and sizes of aerosol particles within wide ranges with the real-time presentation of results both in laboratory and in situexperiments.
Analysis of monitoring data for long-term air pollution with benzo(a)pyrene in Irkutsk
Authors: РАПУТА В.Ф. , ЛЕЖЕНИН А.А.
Published: July 2024

Экспериментальные исследования состава атмосферного воздуха являются основой для последующего численного анализа процессов загрязнения и принятия управленческих решений по улучшению качества городской среды. Представлены результаты исследования процессов длительного загрязнения атмосферы г. Иркутска и влияния на них штилевых условий. Выполнен анализ линейных корреляционных связей между результатами измерений среднемесячных концентраций бенз(а)пирена на стационарных постах контроля состава атмосферного воздуха города. Показано, что результаты внутригодовых измерений на постах в целом пропорциональны друг другу. Исследованы связи концентрации бенз(а)пирена со штилевыми условиями. Выявлена корреляция между его высокими концентрациями в зимний период и повторяемостью штилей. Установленные закономерности создают возможности для внешнего контроля результатов наблюдений на стационарных постах мониторинга города. Найденные зависимости позволяют численно восполнять пропуски в данных наблюдений. Полученные результаты могут быть использованы при планировании мероприятий по улучшению качества атмосферного воздуха, построении моделей оценивания полей концентраций бенз(а)пирена.

Experimental studies of the composition of atmospheric air are the basis for subsequent numerical analysis of pollution processes and management decisions to improve the quality of the urban environment. The processes of long-term air pollution in Irkutsk and the influence of calm conditions on them are studied. An analysis of linear correlations between the measurements of monthly average concentrations of benzo(a)pyrene at stationary posts for monitoring the composition of atmospheric air in the city is performed. It is shown that the results of intra-annual pairwise measurements at posts, in general, are proportionally correlated to each other. The relationships between benzo(a)pyrene concentrations and calm conditions were studied. A correlation between its high concentrations in winter and the frequency of calm weather conditions is revealed. The established patterns create opportunities for external monitoring of observation results at stationary monitoring posts in the city. The derived dependencies allow you to numerically fill gaps in observational data. The results can be used when planning measures to improve the quality of atmospheric air and constructing models for assessing concentration fields.
Sensitivity of the model of methane emission from the Arctic shelf seas to the parameterization of the gas exchange process
Authors: МАЛАХОВА В.В. , КРАЙНЕВА М.В.
Published: July 2024

Существует значительная неопределенность в отношении масштабов эмиссии метана из морей арктического шельфа. Потоки метана в этом регионе могут быть недооценены и играть значимую роль из-за большого объема газа, который содержится в донных отложениях в слое многолетнемерзлых пород и газовых гидратов. Проведен анализ чувствительности модели эмиссии метана к параметризации процессов газообмена на поверхности моря на основе результатов численного моделирования переноса растворенного метана в морях Арктики. Модель переноса растворенного метана включена в базовую модель океана и морского льда SibCIOM, разработанную в ИВМиМГ СО РАН. Оценки эмиссии метана в атмосферу выполнены на основе различных соотношений для параметризации процесса газообмена в системе «вода – атмосфера» и «вода – лед – атмосфера» с использованием данных реанализа NCEP/NCAR. Неопределенность оценки годовой эмиссии метана составила 6–12% с учетом различных зависимостей коэффициента газообмена от ветра. Более выраженное влияние при расчете потока оказывает схема учета ледового покрова – неопределенность увеличилась до 50–130%. Параметризация взаимосвязи между ледовым покровом и газообменом может оказывать большое влияние на расчетные потоки метана и приводить к недооценке его эмиссии из морей арктического шельфа.

There is considerable uncertainty about the methane emission from the Arctic shelf seas. Methane fluxes in this region can be underestimated and play a significant role due to the large volume of gas contained in bottom sediments in the permafrost and gas hydrates. We have analyzed the model sensitivity to the parametrization of gas exchange processes on the sea surface. The study is based on the numerical modeling results of the transport of dissolved methane in the seas of the Arctic. The dissolved methane transport model is included in the basic model of the ocean and sea ice developed at the Institute of Computational Mathematics and Mathematics, Siberian Branch, Russian Academy of Sciences. Estimates of methane emissions into the atmosphere were made with various parametrization of the gas exchange process in the "water – atmosphere" and "water – ice – atmosphere" systems using NCEP/NCAR reanalysis data. The uncertainty of the estimate of annual methane emission amounted to 6–12% when considering different dependencies of gas exchange on wind. The scheme accounting the ice cover has a more pronounced influence on the flux: the uncertainty increased to 50–130%. Parameterization of the relationship between ice cover and gas exchange can have a great influence on the calculated methane fluxes and lead to underestimation of its emission from the seas of the Arctic shelf.
Dynamics of species diversity of the small mammal community in slope larch forests of Northern Coast of the Sea of Okhotsk
Authors: Дубинин Е.А.
Published: July 2024

В 2010–2023 гг. прослежены динамика численности популяций и изменение долевого участия видов в составе сообщества мелких млекопитающих (насекомоядных и грызунов), населяющих склоновый лиственничный лес в окрестностях г. Магадана (Северное Приохотье). Учеты зверьков осуществлялись методами ловушко-линий с использованием ловушек Геро и конусов. В общей сложности отработано 4700 ловушко-суток и 15 720 конусо-суток, поймано 3384 экз. мелких млекопитающих девяти видов, принадлежащих семействам бурозубок (Soricidae), беличьих (Sciuridae), мышиных (Muridae) и хомячьих (Cricetidae). За рассматриваемый период в популяциях равнозубой бурозубки (Sorex isodon) и красно-серой полевки (Craseomys rufocanus) уменьшились относительная численность и амплитуда ее межгодовых колебаний. Доли средней бурозубки (S. caecutiens) и восточноазиатской лесной мыши (Apodemus peninsulae) в сообществе увеличились соответственно в 2,6 и 2,5 раза, одновременно сократившись у равнозубой бурозубки в 2,8 раза и у красно-серой полевки в 3 раза. В результате около 50 % особей в выборках стали принадлежать средней бурозубке и около 30 % – красной полевке (Clethrionomys rutilus). Это, в свою очередь, привело к усилению доминирования (индекс доминирования Симпсона увеличился с 0,21 до 0,34), снижению выравненности (индекс Пиелу сократился с 0,87 до 0,61) и достоверному уменьшению видового разнообразия сообщества мелких млекопитающих (индекс Шеннона сократился с 1,7 до 1,3; t= 10,90,p< 0,001).

In 2010–2023 the dynamics of population numbers and changes in the share of species in the community of small mammals (insectivores and rodents) inhabiting a slope larch forest in the vicinity of Magadan (Northern Coast of the Sea of Okhotsk) were traced. Сensuses of animals were carried out using trap-line methods, using Gero traps and cones. A total of 4.700 trap-days and 15.720 cone-days were worked. 3.384 individuals of 9 species belonging to the families of shrews (Soricidae), squirrels (Sciuridae), mice (Muridae) and hamsters (Cricetidae) were caught. During the period under review, the relative abundance and the amplitude of its interannual fluctuations decreased in the populations of the equal-toothed shrew (Sorex isodon) and the red-gray vole (Craseomys rufocanus). The shares of the Laxmann’s shrew (S. caecutiens) and the East Asian wood mouse (Apodemus peninsulae) in the community increased by 2.6 and 2.5 times, respectively, while simultaneously decreasing in the equal-toothed shrew by 2.8 times and in the red-gray vole by 3 times. As a result, about 50 % of the individuals in the samples began to belong to the Laxmann’s shrew and about 30 % to the red-backed vole (Clethrionomys rutilus). This, in turn, led to increased dominance (the Simpson index increased from 0.21 to 0.34), a decrease in evenness (the Pielou index decreased from 0.87 to 0.61) and a significant decrease in the species diversity of the small mammal community (the Shannon Index decreased from 1.7 to 1.3; t = 10.90, p< 0.001).
Analysis of the Stress State of a Layer with Two Cylindrical Swivel Joints and a Cylindrical Cavity
Authors: Miroshnikov Vitalii Yu. ,   National Aerospace University Kharkiv Aviation Institute, Pelykh Valentyn P. , Denshchykov Oleksandr Yu. ,   National Aerospace University Kharkiv Aviation Institute,   National Aerospace University Kharkiv Aviation Institute
Published: July 2024

In practice, connections in the form of cylindrical swivel joints are often encountered. However, exact methods for calculating such models are absent. Therefore, the development of algorithms to solve such problems is relevant. In this study, a spatial elasticity problem is solved for an infinite layer with two cylindrical swivel joints and a cylindrical cavity positioned parallel to each other and parallel to the layer surfaces. The embedded cylindrical swivel joints are represented as cavity with given contact-type conditions (normal displacements and tangential stresses). Stresses are specified on the layer surfaces and the cavity surface. The layer is considered in a Cartesian coordinate system, while the cylindrical cavities are considered in local cylindrical coordinates. The spatial elasticity problem is solved using the generalized Fourier method applied to the Lamé equations. Satisfying the boundary conditions results in a system of infinite linear algebraic equations, which undergo reduction methods. In the numerical study, the accuracy of boundary condition fulfillment reached 10-3 for stress values ranging from 0 to 1, with the equation system (Fourier series members) order of m=4. As the order of the system equations increases, the accuracy of calculations increases. Stress state analysis was conducted at varying distances between supports. The obtained results indicate that with an increased distance between supports, stresses on the supporting cylindrical surfaces of the layer and the cylindrical cavity surface decrease. These stresses are redistributed to the upper and lower surfaces of the layer, where the stresses increase and exceed the specified ones. The numerical outcomes can be applied to predict geometric parameters during design processes.
Identification and Management of Ankyloglossia and Its Effect on Breastfeeding in Infants: Clinical Report
Authors: Thomas Jennifer , Bunik Maya , Holmes Alison , Keels Martha Ann , Poindexter Brenda , Meyer Anna , Gilliland Alison ,   SECTION ON BREASTFEEDING, Long Sahira , Richter Monica , Hannon Emily , Kellams Ann , Williams Tara , Feldman-Winter Lori , Mass Sharon , Noble Larry , St. Fleur Rose , Stellwagen Lisa , Thomas Jennifer , Younger Meek Joan , O’Connor Mary , Ware Julie , Beskin Kera , Onyema-Melton Ngozi ,   SECTION ON ORAL HEALTH, Karp Jeffrey M. , Beyer Eric , Brooks Chevon , Kimball C. Eve , Tate Anupama Rao , Feldman Lauren , Zaborowski Matt , Crespin Matt , Moursi Amr , Beskin Kera ,   COUNCIL ON QUALITY IMPROVEMENT AND PATIENT SAFETY, Shaikh Ulfat , Alvarez Francisco Javier , Chuo John , Drayton Jackson Meghan , Kim Julia M. , Miotto Mary Beth , Paul Raina , Rea Corinna , Spencer Sandra , Tyler Amy , Vachani Joyee , Guch Cathleen ,   COMMITTEE ON FETUS & NEWBORN, Eichenwald Eric , Ambalavanan Namasivayam , Guillory Charleta , Hudak Mark , Kaufman David , Martin Camilia , Lucke Ashley , Parker Margaret , Pramanik Arun , Wade Kelly , Jancelewicz Timothy , Narvey Michael , Miller Russell , Barfield Wanda , Grisham Lisa , Couto Jim ,   SECTION ON OTOLARYNGOLOGY-HEAD AND NECK SURGERY, Simons Jeffrey Philip , Sobol Steven E. , Dedhia Kavita , Gallagher Thomas , Kelley Peggy Elaine , Mudd Pamela Anne , Ostrower Samuel , Raynor Eileen Margolies , Reilly Brian Kip , Windsor Alanna , Thorne Vivian B.
Published: July 2024

Ankyloglossia refers to a congenitally tight lingual frenulum that limits the motion of the tongue. Whether the release of a tight lingual frenulum in neonates improves breastfeeding is not clear. Because many of the symptoms of ankyloglossia overlap those of other breastfeeding difficulties, a team partnership is necessary.
Description of feather mite Proctophyllodes musicus (Acariformes, Proctophyllodidae) obtained from Turdus merula
Authors: Melnychuk V. , Yevstafieva V. , Kolomak I. , Muzyka D. , Chaplygina A. , Filonenko S. , Opara N.
Published: July 2024

Feather mites (Acariformes, Astigmata) are a large group of species in which mites of the genus Proctophyllodes Robin, 1868. Analgoidea are among the most common parasites of passerines. These mites are permanent obligate ectoparasites localized on the flight feathers, greater wing coverts, and on the tail. Most species of feather mites are characterized by high host specificity. The taxonomy and fauna of feather mites of the genus Proctophyllodes, and their morphological identification characters in different countries of the world are still a matter of research. The aim of our work was to describe the morphological features and metric parameters of feather mites of the species P. musicus Vitzthum, 1922, isolated from the common blackbird Turdus merula Linnaeus, 1758 in Ukraine. 32 parameters are determined in males and females of P. musicus mites, which characterize both their general structure of the body and sexual dimorphism. The structure and sizes of the body, gnathosoma, idiosoma, prodorsal and hysteronotal shields, epimerites I, setae cp and c3, and the distance between setae of the scapula se–se and si–si are described. In males, the sizes of adanal sucker discs, epigastric shields, genital arch, setae ps2, h3, h2, the distance between setae 4a–4a, g–g, ps3–ps3, ps1–ps1 are additionally described and determined. Lamellae in males are wide, tongue-shaped, do not overlap. The aedeagus is short, slightly extending beyond the posterior margin of the genital arch. In female mites, the dimensions of the lobar shield, terminal appendages, and terminal recess are additionally described and determined, taking into account the location of setae ps1, h2, the dimensions of setae cp, c3, h3, h2, the distance between setae h1–h1, the distance between hysteronotal and lobar shields. The mite eggs were measured in the body of the female and on the feathers of the birds. The scientific data obtained in this study expand the already existing data on morphological and metric characters of feather mites of the species P. musicus (Proctophyllodidae) isolated from the common blackbird.