bluuebunny/crossref_metadata_2025 huggingface dataset:
Design and Simulation of Two-Wheeled Balancing Mobile Robot with PID Controller
Authors: Mudeng Vicky , Hassanah Barokatun , Priyanto Yun Tonce Kusuma , Saputra Okcy ,   Department of Electrical Engineering, Institut Teknologi Kalimantan, Indonesia,   National Center for Sustainable Transportation Technology, Indonesia,   Department of Electrical Engineering, Institut Teknologi Kalimantan, Indonesia,   Department of Electrical Engineering, Institut Teknologi Kalimantan, Indonesia,   National Center for Sustainable Transportation Technology, Indonesia,   Department of Electrical Engineering, Institut Teknologi Kalimantan, Indonesia
Published: April 2020

Mobile transportation robots using two wheels have now been investigated. The work within this study is to design and simulate two-wheeled robots, thus it can maintain its balance. Many control methods are used to determine satisfactory control optimization, therefore a proper response is obtained by sensor recitation corresponding with the reaction of a Direct Current (DC) motor. Recently, two-wheeled transportation robot is a Segway model. In this study, we apply a Proportional Integral Derivative (PID) controller as a control system in a self-balancing robot with a working principle is similar to an inverted pendulum. In the next study, the PID controller and the whole system are applied in the microcontroller board. The angular velocity of two DC motors used as a plant can be adjusted by Pulse Width Modulation (PWM) through a motor driver. An Inertial Measurement Unit (IMU) sensor is utilized to detect the angular acceleration and angular velocity of the self-balancing robot. The phase design is constructed by planning the robot dimension, mechanical system, and an electronic system. Particularly, this study performs mathematical modeling of the robot system to obtain the transfer function. In addition, we simulate the PID parameter with multiplication between the basic parameter and several fixed constants. The simulation results indicate that the robot can maintain its balance and remains perpendicularly stable for balancing itself.
Türkçede İlgi Tümceciği Adası Dışına Yapılan Taşımalar Üzerine Bir İnceleme
Authors: ÇAKIR Sinan
Published: April 2020

ÖZ: Geç Eklenti Varsayımına (Stepanov, 2001; 2007; Fox, 2002; Boskovic, 2004; Henderson, 2007) göre eklentiler türetime diğer tümce öğelerine kıyasla daha geç katılmaktadırlar. Bu nedenle de bu tür yapılardan dışarı doğru taşıma yapmak mümkün olmamaktadır. Türkçede ilgi tümceciği eklenti adası dışına yapılan taşımaları inceleyen çalışmaların bulguları (Gürel ve Çele, 2011, İnce, 2012, Çakır, 2018) Geç Eklenti Varsayımının iddialıyla örtüşmektedir. Ancak Hoffman (1995, s.56-57), Türkçede kişi adılı kullanılan bazı durumlarda ilgi tümcecikleri gibi oldukça güçlü eklenti adalarından bile öğelerin dışarı taşınabildiğini iddia etmektedir. Mevcut çalışma, bu tür yapılara odaklanmaktadır. 18 maddeden oluşan Bir Dilbilgisellik Değerlendirme Testi ve 9 maddeden oluşan Bireysel Hızda Belirlenen Hızda Okuma Testi (Self-paced Reading Test) ile toplam 93 katılımcıdan veri toplanmıştır. Çalışmanın bulguları Geç Eklenti Varsayımının iddialarını desteklemektedir. İlgi tümceciği içeren tümcenin öznesi konumunda ister bir kişi adılı bulunsun ister diğer bir ad öbeği, bu tümcecikten dışarı doğru yapılan taşımalar dilbilgisel sonuçlar vermemektedir. Kişi adılı içeren tümcelerde, ilgi tümceciğinden dışarı doğru yapılan taşımaların göreceli olarak daha fazla kabul edilebilir oluşu ise bu tümcelerde bulunan açık adılların zihinsel işlemleme esnasında düşürüldüğü şeklinde açıklanmıştır. Çalışma bulgularının da gösterdiği gibi, açık adılların başka ad öbekleri ile değiştirilmesiyle bu tür taşımalardaki dilbilgisellik sorunu daha belirgin bir hale gelmektedir.  Anahtar sözcükler: Geç Eklenti Varsayımı, İlgi Tümceciği Adası, açık adıllar, Türkçe.
Seçilmiş On Bir Eserden Hareketle Orhon, Uygur ve Karahanlı Türkçesinde Ur- Eyleminin Durum Ekli Tamlayıcıları Üzerine
Authors: ÇAKMAK Vildan
Published: April 2020

Fiil ile tamlayıcı arasındaki ilişki Türkiye’de
araştırmacılar tarafından İstem Dil Bilgisinin bir kolu olarak incelenmiştir.
Aynı zamanda fiil tamlayıcısı, Türkiye’de istem terimini karşılamak için
kullanılmış, yapılan çalışmalarda özellikle durum ekli tamlayıcılar üzerinde
durulmuştur. Bu çalışmada da ur-
eyleminin Orhon, Uygur ve Karahan Türkçelerindeki durum ekli tamlayıcıları ve
tamlayıcılara göre anlam değişimleri tespit edilmeye çalışılmıştır. Çalışmada
mantıksal ve söz dizimsel istem türleri dikkate alınmıştır. Buna göre ur- eyleminin söz konusu üç dönemde on
yedi anlamı saptanmış ve bir örnek dışında çoğunlukla iki veya daha fazla
zorunlu istem aldığı görülmüştür.
Türkçe Öğretmeni Adaylarının Çocuk Kitaplarının Tasarım, İçerik ve Eğitsel Özelliklerine Yönelik Yeterliklerinin İncelenmesi
Authors: ÇER Erkan
Published: April 2020

ÖZ: Bu araştırmanın amacı, Türkçe öğretmeni adaylarının çocuk
kitaplarının tasarım, içerik ve eğitsel özelliklerine yönelik yeterliklerini
incelemektir. Böylelikle öğretmen adaylarının çocuk kitaplarının tasarım,
içerik ve eğitsel özelliklerine yönelik bilgi düzeyleri ortaya çıkartılabilir. Kesitsel araştırma modelinin kullanıldığı bu araştırmanın
çalışma grubunu bir üniversitede Türkçe Öğretmenliği programına devam etmekte olan
251 öğretmen adayı oluşturmaktadır. Araştırma
verileri “Çocuk Kitaplarının Tasarım, İçerik ve Eğitsel Özelliklerine Yönelik
Değerlendirme Formu” ile “Genel Bilgi Formu” ile toplanmış ve bu veriler “Tek Yönlü ANOVA” ile “Tamamlayıcı Post-Hoc” kullanılarak
çözümlenmiştir. Sonuç olarak, bu
araştırma üçüncü ve dördüncü sınıfta yer alan Türkçe öğretmeni adaylarının çocuk kitaplarının tasarım,
içerik ve eğitsel özellikleri ile ilgili değerlendirme ölçütlerine yönelik
yeterli düzeyde bilgi sahibi olduğunu ortaya koymaktadır. Bu araştırmanın sonuçlarına yönelik olarak sunulacak
öneri ise, Türkiye'nin farklı bölgelerinden
seçilecek üniversitelerin Türkçe Öğretmenliği programları üzerinde öğretmen
adaylarının çocuk kitaplarının tasarım, içerik ve eğitsel özelliklerine yönelik
değerlendirme ölçütlerini bilip bilmediği ile ilgili araştırmaların yapılmasıdır.

Anahtar sözcükler: Türkçe öğretmeni
adayları, çocuk kitaplarının tasarım, içerik ve eğitsel özellikleri, yeterlik düzeyleri
Дискурс транскультурації в сучасних британських романах: ревізія архетипу Дому
Authors: Drozdovskyi Dmytro
Published: April 2020

Теорія транскультурності (Ф. Ортіс) набуває особливої значущості в річищі сучасного літературознавства й культурології, об’єктами яких є гібридні культурні явища. Транскультурність заміщує мультикультуралізм, який не передбачає трансферу сенсів, цінностей, досвіду, культурних феноменів тощо, а лише утверджує їх наявність в одному геополітичному й соціокультурному полі. Транскультурність дає можливість розглядати культурні артефакти як складні явища, позначені іманентною неоднорідністю й негомогенністю, що водночас і забезпечує особливу креативну цінність і культурну значущість таких феноменів. У вітчизняному й зарубіжному літературознавстві окреслення транскультурації представлено у працях Г. Бгабги, І. Оржицького, Т. Свербілової, М. Тлостанової та ін. Проте найчастіше у студіях здійснено історичний огляд форм становлення дискурсу транскультурації та основних теоретичних концептів (ідей), реалізованих у лоні цього дискурсу. У пропонованій статті, що є спробою розвитку ідей, належних до дискурсу транскультурації, йдеться про окреслення архетипу Дому як визначального в літературі концепту й водночас такого, що сьогодні позначений впливом транскультурації, яка призводить до зміщення іманентної сутності цього архетипу в сучасному романі Великої Британії та США. Трансформації підлягають такі базові уявлення, що корелюють із архетипом Дому, як безпека, захист, комфорт тощо. У романах, написаних після 2000-го р., вихід за межі власного етнічного простору, дає можливість персонажам вийти на новий рівень соціальної безпеки, гарантування цінності власного життя, натомість перебування в межах локусу дому позначене небезпеками й потенційними загрозами життю. У статті порушено питання про трансформацію базового архетипу світової культури й літератури в парадигмі постпостмодернізму. Заміна іманентних рис архетипу Дому співвідноситься з концептом «заміщення» («displacement»), широко представленому в сучасній британській теорії літератури.
Gender Peculiarities of English-Language Internet Communication
Authors: Handabura Oksana
Published: April 2020

The article is devoted to the enrichment of the contemporary English language with the neologisms used in the social networks, particularly in Facebook and Twitter. The author has researched the essence of the notion «neologism», its types and ways of formation. The influence of the Internet and social networks Facebook and Twitter on the change of the English language lexicon has been thoroughly investigated.

The examples of morphological and semantic neologisms from Facebook and Twitter social networks, the process of their formation and meaning have been presented. The author has determined the most productive ways of neologisms’ formation.
Сонце як компонент мовного полотна повісті «Небесний змій» Докії Гуменної
Authors: Filiniuk Valentyna
Published: April 2020

У статті досліджено лексико-семантичні та стилістичні особливості функціонування слова сонце у фантастичній повісті Докії Гуменної «Небесний змій». Було використано функціонально-семантичний аспект для виявлення лексико-семантичних зв’язків між словами, семантичного наповнення лексем, актуалізації різних сем для передачі авторського задуму. Було зафіксовано близько 80 випадків уживання слова сонце. Цей лексичний компонент в аналізованій повісті значно розширив семантичне поле. Окрім, зафіксованих у словниках значень слова сонце, ми виявили такі семи: ʽсторона світуʼ, ʽджерело світлаʼ, ʽастрономічне поняттяʼ, ʽформаʼ, ʽнапрям рухуʼ, ʽчасʼ, ʽколоʼ, ʽвізерунокʼ, ʽбожествоʼ, ʽлюдинаʼ. Найчастіше Докія Гуменна пише про сонце як персоніфіковану істоту, оживлене явище природи. Могутньому богу Сонця, який щороку народжувався, поклонялися представники різних народів, зображених у творі. Антропоморфні та зооморфні образи втілення сонячного божества (бик, кінь, олень) творяться за участю дієслівних і прикметникових лексем. Було проаналізовано низку перифразів, метафоричних і порівняльних конструкцій із компонентом сонце. Дослідження доповнено семантичним аналізом спільнокореневих слів сонячний, підсоння.
Management of Traumatic Spinal Fracture in the Coronavirus Disease 2019 Situation
Authors: Sornsa-ard Tuanrit , Niramitsantiphong Anugoon , Liawrungrueang Wongthawat
Published: April 2020

The coronavirus outbreak was labeled a pandemic by the World Health Organization in 2020. Patients who require spine surgery should receive coronavirus disease 2019 (COVID-19) screening to prevent nosocomial cross-infection before surgery. However, spine fracture and spinal injury are critical and serious, and there are no standard protocols for management. This article aims to propose a treatment algorithm for the management of traumatic spine fracture during the COVID-19 pandemic.
Long-term outcomes after surgery for catastrophic epilepsy in infants: institutional experience and review of the literature
Authors: Ye Vincent C. , Shah Ashish H. , Sur Samir , Achua Justin K. , Wang Shelly , Ibrahim George M. , Bhatia Sanjiv , Ragheb John
Published: April 2020

OBJECTIVE

Uncontrolled epilepsy is associated with serious deleterious effects on the neurological development of infants and has been described as “catastrophic epilepsy.” Recently, there has been increased emphasis on early surgical interventions to preserve or rescue neurodevelopmental outcomes in infants with early intractable epilepsy. The enthusiasm for early treatments is often tempered by concerns regarding the morbidity of neurosurgical procedures in very young patients. Here, the authors report outcomes following the surgical management of infants (younger than 1 year).

METHODS

The authors performed a retrospective review of patients younger than 1 year of age who underwent surgery for epilepsy at Miami (Nicklaus) Children’s Hospital and Jackson Memorial Hospital between 1994 and 2018. Patient demographics, including the type of interventions, were recorded. Seizure outcomes (at last follow-up and at 1 year postoperatively) as well as complications are reported.

RESULTS

Thirty-eight infants (median age 5.9 months) underwent a spectrum of surgical interventions, including hemispherectomy (n = 17), focal resection (n = 13), and multilobe resections (n = 8), with a mean follow-up duration of 9.1 years. Hemimegalencephaly and cortical dysplasia were the most commonly encountered pathologies. Surgery for catastrophic epilepsy resulted in complete resolution of seizures in 68% (n = 26) of patients, and 76% (n = 29) had a greater than 90% reduction in seizure frequency. Overall mortality and morbidity were 0% and 10%, respectively. The latter included infections (n = 2), infarct (n = 1), and immediate reoperation for seizures (n = 1).

CONCLUSIONS

Surgical intervention for catastrophic epilepsy in infants remains safe, efficacious, and durable. The authors’ work provides the longest follow-up of such a series on infants to date and compares favorably with previously published series.
Relationship between direct cortical stimulation and induced high-frequency activity for language mapping during SEEG recording
Authors: Cuisenier Pauline , Testud Bénédicte , Minotti Lorella , El Bouzaïdi Tiali Samuel , Martineau Laurence , Job Anne-Sophie , Trébuchon Agnès , Deman Pierre , Bhattacharjee Manik , Hoffmann Dominique , Lachaux Jean-Philippe , Baciu Monica , Kahane Philippe , Perrone-Bertolotti Marcela
Published: April 2020

OBJECTIVE

The authors assessed the clinical relevance of preoperative task-induced high-frequency activity (HFA) for language mapping in patients with refractory epilepsy during stereoelectroencephalography recording. Although HFA evaluation was described as a putative biomarker of cognition, its clinical relevance for mapping language networks was assessed predominantly by studies using electrocorticography (ECOG).

METHODS

Forty-two patients with epilepsy who underwent intracranial electrode implantation during both task-induced HFA and direct cortical stimulation (DCS) language mapping were evaluated. The spatial and functional relevance of each method in terms of specificity and sensitivity were evaluated.

RESULTS

The results showed that the two methods were able to map classic language regions, and a large and bilateral language network was obtained with induced HFA. At a regional level, differences were observed between methods for parietal and temporal lobes: HFA recruited a larger number of cortical parietal sites, while DCS involved more cortical temporal sites. Importantly, the results showed that HFA predicts language interference induced by DCS with high specificity (92.4%; negative predictive value 95.9%) and very low sensitivity (8.9%; positive predictive value 4.8%).

CONCLUSIONS

DCS language mapping appears to be more appropriate for an extensive temporal mapping than induced HFA mapping. Furthermore, induced HFA should be used as a complement to DCS to preselect the number of stimulated sites during DCS, by omitting those reported as HFA−. This may be a considerable advantage because it allows a reduction in the duration of the stimulation procedure. Several parameters to be used for each method are discussed and the results are interpreted in relation to previous results reported in ECOG studies.
Clip retraction of the tentorium: application of a novel technique for tentorial retraction during supracerebellar transtentorial approaches
Authors: Baranoski Jacob F. , Bajaj Ankush , Przybylowski Colin J. , Catapano Joshua S. , Frisoli Fabio A. , Lang Michael J. , Lawton Michael T.
Published: April 2020

Supracerebellar transtentorial (SCTT) approaches have become a popular option for treatment of a variety of pathologies in the medial and basal temporal and occipital lobes and thalamus. Transtentorial approaches provide numerous advantages over transcortical approaches, including obviating the need to traverse eloquent cortex, not requiring parenchymal retraction, and circumventing critical vascular structures. All of these approaches require a tentorial opening, and numerous techniques for retraction of the incised tentorium have been described, including sutures, fixed retractors, and electrocautery. However, all of these techniques have considerable drawbacks and limitations. The authors describe a novel application of clip retraction of the tentorium to the supracerebellar approaches in which an aneurysm clip is used to suspend the tentorial flap, and an illustrative case is provided. Clip retraction of the tentorium is an efficient, straightforward adaptation of an established technique, typically used for subtemporal approaches, that improves visualization and surgical ergonomics with little risk to nearby venous structures. The authors find this technique particularly useful for the contralateral SCTT approaches.
An altered posterior question-mark incision is associated with a reduced infection rate of cranioplasty after decompressive hemicraniectomy
Authors: Veldeman Michael , Daleiden Lorina , Hamou Hussam , Höllig Anke , Clusmann Hans
Published: April 2020

OBJECTIVE

Performing a cranioplasty (CP) after decompressive craniotomy is a straightforward neurosurgical procedure, but it remains associated with a high complication rate. Surgical site infection (SSI), aseptic bone resorption (aBR), and need for a secondary CP are the most common complications. This observational study aimed to identify modifiable risk factors to prevent CP failure.

METHODS

A retrospective analysis was performed of all patients who underwent CP following decompressive hemicraniectomy (DHC) between 2010 and 2018 at a single institution. Predictors of SSI, aBR, and need for allograft CP were evaluated in a univariate analysis and multivariate logistic regression model.

RESULTS

One hundred eighty-six patients treated with CP after DHC were included. The diagnoses leading to a DHC were as follows: stroke (83 patients, 44.6%), traumatic brain injury (55 patients, 29.6%), subarachnoid hemorrhage (33 patients, 17.7%), and intracerebral hemorrhage (15 patients, 8.1%). Post-CP SSI occurred in 25 patients (13.4%), whereas aBR occurred in 32 cases (17.2%). An altered posterior question-mark incision, ending behind the ear, was associated with a significantly lower infection rate and CP failure, compared to the classic question-mark incision (6.3% vs 18.4%; p = 0.021). The only significant predictor of aBR was patient age, in which those developing resorption were on average 16 years younger than those without aBR (p < 0.001).

CONCLUSIONS

The primary goal of this retrospective cohort analysis was to identify adjustable risk factors to prevent post-CP complications. In this analysis, a posterior question-mark incision proved beneficial regarding infection and CP failure. The authors believe that these findings are caused by the better vascularized skin flap due to preservation of the superficial temporal artery and partial preservation of the occipital artery. In this trial, the posterior question-mark incision was identified as an easily and costless adaptable technique to reduce CP failure rates.
Episodio maníaco tras la administración simultánea de 4 vacunas: relación temporal frente a relación causal. A propósito de un caso
Authors: Real-López M. , Fuertes-Saiz A. , Prades Salvador N. , Ruiz-Palomino E. , Ramos-Vidal C.
Published: April 2020

Ante un cambio radical en el comportamiento en un varón de 17 años, a las 12 horas de administrar, en el mismo día, las vacunas contra el Meningococo C, Hepatitis B, Triple Vírica y Varicela, y la detección de un cuadro maníaco a la semana, se sospechó que se tratase de un cuadro de encefalitis post-vacunal. A pesar de la ausencia de hallazgos patológicos en las exploraciones complementarias realizadas, y aunque en la literatura científica no se haya demostrado una asociación temporal a día de hoy, no podemos aceptar ni descartar con certeza la sospecha diagnóstica dado que no contamos con la serología infecciosa o un estudio de anticuerpos en líquido cefalorraquídeo. Los efectos secundarios graves tras vacunaciones no han quedado claramente demostrados, lo que sí está ampliamente demostrado es que la inmunidad adquirida es uno de los mayores logros de la medicina que ha ayudado a erradicar enfermedades potencialmente mortales.
A model for determining the operating costs of machine-tractor units for sowing, taking into account the duration of work and the size of the area
Authors: Starcev A. V , Alushkin T. E , Romanov S. V , Storozhev I. I
Published: April 2020

The article presents an analysis of the impact of the performance of machine-tractor units on the duration of technological work in crop production. The results of a survey among specialists of agricultural organizations of the Tomsk region, indicating a significant influence of the technical factor in general on the productivity of machinery (33,9 %), are presented. An interpretation of the survey results is given and, based on these data, a rationale is formulated to create a methodology for optimizing the technological parameters of sowing units. The aim of the work is to develop a methodology for optimizing the technological parameters of sowing units, compiled on the basis of different models of tractors by the criterion of minimum operating costs. The scientific novelty is the introduction of the indicator «unit operating costs of the sowing unit», which explains the choice of a tractor of a certain traction class taking into account the used sowing machines. As a result of the calculations, the fact of a nonlinear dependence of the productivity of the sowing units on the installed tractor power was confirmed. For the given conditions (sowing days, sown area), various sowing units were selected and the costs of their operation were calculated. As a result of mathematical modeling, the operating costs of various sowing units are determined in standard and reduced tractor engine power options. To assess the specific operating costs of the sowing unit for processing a unit area, an appropriate indicator and its graphical interpretation are proposed. The dependences of the indicator of specific operating costs on the power of the tractor engine with its installed (nominal) value and reduced to 15 % are obtained. If the engine power meets the set value, the optimal sowing machine and tractor unit according to the criterion of minimum specific operating costs is the unit based on a wheeled tractor with an engine power of 125 kW, which corresponds to 2 or 3 drawbar category. It was found that a decrease in tractor engine power by 15 % from the installed one, due to a change in its technical condition, provides an increase in unit costs for sowing by 28,4 %.
The Association of Osteoarthritis and Related Pain Burden to Incident Alzheimer’s Disease and Related Dementias: A Retrospective Cohort Study of U.S. Medicare Beneficiaries
Authors: Innes Kim E. , Sambamoorthi Usha
Published: April 2020

Background:

Emerging evidence suggests osteoarthritis (OA) and related symptom burden may increase risk for Alzheimer’s disease and related dementias (ADRD). However, longitudinal studies are sparse, and none have examined the potential mediating effects of mood or sleep disorders.

Objective:

To determine the association of OA and related pain to incident ADRD in U.S. elders.

Methods:

In this retrospective cohort study, we used baseline and two-year follow-up data from linked Medicare claims and Medicare Current Beneficiary Survey files (11 pooled cohorts, 2001–2013). The study sample comprised 16,934 community-dwelling adults≥65 years, ADRD-free at baseline and enrolled in fee-for-service Medicare. Logistic regression was used to assess the association of OA and related pain (back, neck, joint, neuropathic) to incident ADRD, explore the mediating inlfuence of mood and insomnia-related sleep disorders, and (sensitivity analyses) account for potential survival bias.

Results:

Overall, 25.5% of beneficiaries had OA at baseline (21.0% with OA and pain); 1149 elders (5.7%) were subsequently diagnosed with ADRD. Compared to beneficiaries without OA, those with OA were significantly more likely to receive a diagnosis of incident ADRD after adjustment for sociodemographics, lifestyle characteristics, comorbidities, and medications (adjusted odds ratio (AOR) = 1.23 (95% confidence interval (CI) 1.06, 1.42). Elders with OA and pain at baseline were significantly more likely to be diagnosed with incident ADRD than were those without OA or pain (AOR = 1.31, CI 1.08, 1.58). Sensitivity analyses yielded similar findings. Inclusion of depression/anxiety, but not sleep disorders, substantially attenuated these associations.

Conclusion:

Findings of this study suggest that: OA is associated with elevated ADRD risk, this association is particularly pronounced in those with OA and pain, and mood disorders may partially mediate this relationship.
Odor Identification Impairment and Change with Cholinesterase Inhibitor Treatment in Mild Cognitive Impairment
Authors: Devanand D. P. , Liu Xinhua , Chunga Richard E. , Cohen Hannah , Andrews Howard , Schofield Peter W. , Stern Yaakov , Huey Edward D. , Choi Jongwoo , Pelton Gregory H.
Published: April 2020

Background:

Anticholinergic challenge can induce odor identification impairment that indicates Alzheimer’s disease (AD) pathology, and short-term change in odor identification impairment with cholinesterase inhibitor (CheI) treatment may predict longer term cognitive outcomes.

Objective:

In patients with mild cognitive impairment (MCI) treated prospectively with donepezil, a CheI, for 52 weeks, to determine if 1) acute decline in odor identification ability with anticholinergic challenge can predict cognitive improvement, and 2) change in odor identification over 8 weeks can predict cognitive improvement.

Methods:

MCI was diagnosed clinically without AD biomarkers. At baseline, the University of Pennsylvania Smell identification Test (UPSIT) was administered before and after an anticholinergic atropine nasal spray challenge. Donepezil was started at 5 mg daily, increased to 10 mg daily if tolerated, and this dose was maintained for 52 weeks. Main outcomes were ADAS-Cog total score and Selective Reminding Test (SRT) total immediate recall score measured at baseline, 26 and 52 weeks.

Results:

In 100 study participants, mean age 70.14 (SD 9.35) years, atropine-induced decrease in UPSIT score at baseline was not associated with change in ADAS-Cog or SRT scores over 52 weeks. Change in UPSIT score from 0 to 8 weeks did not show a significant association with change in the ADAS-Cog or SRT measures over 52 weeks.

Conclusion:

These negative findings in a relatively large sample of patients with MCI did not replicate results in much smaller samples. Change in odor identification with anticholinergic challenge, and over 8 weeks, may not be useful predictors of cognitive improvement with CheI in patients with MCI.
CONTROL NOVEL MODEL OF KNEE CPM DEVICE
Authors: Tu Thanh Diep Cong
Published: April 2020

In recent years, CPM - Continuous Passive Motion has been proved to be one of the most effective therapeutic methods for patients who have problems with motion such as spinal cord injury, ankle and knee injury, parkinson and so on. Many commercial CPM devices are found in market but all of them use motors as the main actuators. The lack of human compliance of electric actuators, which are commonly used in these machines, makes them potentially harmful to patients. An interesting alternative, to electric actuators for medical purposes, particularly promising for rehabilitation, is a pneumatic artificial muscle (PAM) actuator because of its high power/weight ratio and compliance properties. However, the highly nonlinear and hysteresis of PAM make it the challenging for design and control. In this study, a PID compensation using neural network control is studied to improve the control performance of the novel model of Knee CPM device.
ANALYSES OF THE THERMAL EFFICIENCY AND THE OUTPUT POWER IN A JOULE-BRAYTON CYCLE
Authors: Le Kien Chi
Published: April 2020

The analyses on Joule-Brayton cycle, which could be used for a high efficiency power generation system, using the temperature and the pressure of compressor have been carried out. As a result, when the ratio of maximum temperature to the minimum temperature in the cycle increased, the thermal efficiency increased. By analyzing the efficiency and the output power, it is understood that the ratio of compressor outlet pressure to the compressor inlet pressure, as well as the pressure ratio across the compressor for maximum thermal efficiency and maximum output power are different. The maximum thermal efficiency could be an important technical parameter; however, the maximum output power is significant in the cost and the size of system. For that reason, depending on the required system for maximum efficiency or for maximum power, the ratio of temperature and pressure are designed
NON-LINEAR ANALYSIS OF COMPOSITE BEAMS WITH PARTIAL INTERACTION
Authors: Le Nghi Luong Bao , Bui Thanh Cong
Published: April 2020

This paper present the displacement-based finite element formulation for the non-linear analysis of composite steel-concrete beams with partial interaction that occurs due to deformation of shear connectors. The formuation considers the non-linear behaviour of materials as well as shear connectors. The finite element for composite beams which is based on Newmark kinematical model has 8 DOF. Numerical applications are perfomed for simply supported beam and continuous beams. The results are compared with experimental data in order to validate the reliability of the formulation. The results are also disscussed for influence of partial interaction and non-linear behaviour of materials as well as shear connectors on behaviour of composite beams.
THE FACTORS EFFECT THE STRENGTH OF MIXING COLUMN
Authors: Dau Ngo Van
Published: April 2020

Basing on collecting and classifying the researches in soil mixing column method, and applying soil mixing column method at Sai Gon East West highway, this article wants to state and analysis the factors that effect strength and stability of mixing column. It also has some comments of applying this method in soil improvement.
A Review : Plasmodium knowlesi
Authors: Kurniawan Betta , Suwandi Jhons Fatriyadi , Mustofa Syazili , Hayati Sri Janahtul
Published: April 2020

Malaria adalah suatu penyakit yang disebabkan oleh parasit yang termasuk dalam anggota spesies dari genus Plasmodium. Plasmodium knowlesi adalah parasit malaria yang ditemukan pada kera ekor-panjang dan ditemukan pertama kali pada tahun 1930 pada spesimen Macaca fascicularis dari Singapura. Pada tahun 2004 dilaporkan terjadi infeksi P. knowlesi pada manusia di Sarawak, Borneo Malaysia dan penemuan ini menjadikan P. knowlesi sebagai spesies parasit malaria kelima yang menginfeksi manusia. Plasmodium knowlesi dapat melangsungkan siklus eritrositiknya dalam waktu 24 jam sehingga dapat menyebabkan progresifitas infeksi yang lebih tinggi dibandingkan plasmodium lainnya. Transmisi P. knowlesi yang beralih menginfeksi manusia melibatkan beberapa faktor, baik secara demografis, lingkungan ataupun kebiasaan individu.
The development of water quality monitoring system using internet of things
Authors: Yasin Sharifah Nurulhuda Tuan Mohd , Yunus Mohd Fauzi Mohd , Wahab Nur Bahiyah Abdul
Published: April 2020

Biological diversity or biodiversity is an important element in the river water management system. The interaction between the various organisms in the river makes it a very complex ecological system. Therefore, water safety issues are a very important issue. Consumer complaints and reports made by the relevant government departments indicate that consumers are dissatisfied with the quality of water supplied. Hence, a concept in which equipment, machines, sensors and devices are connected to the Internet and there is data collection and transfer through the network developed to follow the river water quality index. Integration of the elements of sustainability and IR4.0 through the Internet of Thing by adopting electronic and Internet applications of Thing has a very positive impact to refresh the approach to lesions in Malaysia. The project aims to develop a wireless water quality monitoring system that aids in continuous measurements of water conditions based on pH and turbidity measurements. The developed system was successfully detecting both the pH and turbidity values. Water analysis and monitoring is a very important aspect of water conservation and protection. Water is a vital resource that runs more quickly overtime. To ensure continued supply of safe, clean drinking water, together as community to protect and to this vital resource.
The effect of different doses of probiotic feed additives on hematologic indices and morphological structure of individual pig internal organs
Authors: Zhyla M. , Shkodyak N. , Kotsyumbas G. , Stronskyi Y. , Sobodosh O. , Shkil M.
Published: April 2020

In order to improve the digestibility and absorption of feed, metabolic processes, growth and development of animals, increase the resistance of the body immunomodulatory agents, probiotics, prebiotics, combined enzyme-probiotic feed additives are widely used. The purpose of our work was to conduct comparative clinical trials of the effectiveness of the probiotic feed additive Probion-forte in terms of productivity, blood indices and histological structure of individual internal  pigs organs during fattening. The researches were carried out on 120 piglets of big white breed at the age of 28 days, which were divided into 4 groups with 30 units in each one. The probiotics were added to feed in different concentrations in order to determine their efficiency and examine influence on piglets organism: the first group was given probiotic Probion-forte in dose of 1.0 g/kg (10 weeks); the second one – Probion in dose of 1.0 g/kg (6 weeks) and 0.5 g/kg (4 weeks); the third one was given probiotic Bio Plus 2B in dose of 0.4 g/kg for 10 weeks; and the fourth one was a control group. The compound feed was provided according to norms recommended for big white breed taking into account age. On the 42nd day (6 weeks) and on the 70th day of test 10 units were selected for haematological, pathomorphological and microbiological tests. The productivity of animals of all studied groups was evaluated by the average daily gains, safety, feed conversion and slaughter output. The stabilized with EDTA piglets’ blood was used for morphological studies, and blood serum – for biochemical studies. The clinical trials have shown that the application of Probion-forte, as a feed additive for fattening of piglets within 10 weeks after weaning, did not cause adverse reactions, was well tolerated by animals and contributed to the improvement of the processes of erythropoiesis and leucopoiesis, increased of serum total protein content. The increasing activity of serum transaminases indicated more intense metabolic processes in experimental animals’ organism, which was confirmed by increase in average daily weight gains and slaughter output compared to control. In the microscopic examination of the thymus, spleen, lymph nodes, intestines, liver, the characteristic histological structure of the organs was preserved and indicated their active morphofunctional state throughout the study period. Morphometrically the increase in the height of the villi in the duodenum and the size of the thymus lobes in piglets, which were fed with probiotic feed additives was established. The efficiency and appropriateness of the application of these products was confirmed in the first and second experimental groups. However, the most significant difference was observed in piglets fed with Probion-forte for 10 weeks at a dose of 1.0 g/kg of feed.
Modern state of fish and fishery products export in Ukraine
Authors: Burhaz M. I. , Matviienko T. I. , Soborova O. M. , Bezyk K. I. , Kudelina O. Y. , Lichna A. I.
Published: April 2020

For every country in the world trade plays an important role in the fishing industry as an employment center, a food supplier, a source of income, a contribution to economic growth and development, as well as it provides food security and nutrition. In fisheries the fierce competition not only for resources but also for markets is not weakening. Leading fishing states are implementing the strategies aimed at ensuring the excellence in both domestic and foreign markets. The purpose of the work was to find out a current state of the fish and fish products export in Ukraine. Based on the specialized literature a current state of the fish and fish products export in Ukraine has been evaluated. A state of the fish and fish products export in Ukraine from 2015 to 2019 was analyzed; the main consumer countries of Ukrainian fish and fish products were identified; the structure of Ukrainian fish and fish products export was analyzed and the ways to increase the export of Ukrainian fish products in the main fish markets of the World were determined. Nowadays Ukraine has excellent resources for growing and catching fish and is gradually gaining the fish markets of many countries around the world. To develop the fishing industry the state constantly allocates the funds that are to support the industrial species of aquatic bio-resources, especially herbivorous fish, which do not breed naturally in Ukraine, to update the material and technical base for genetic research and cryopreservation work, etc. It was established that in recent years there is a tendency to increase the export of fish and fishery products of Ukraine in the markets of different countries of the World. In 2015 this figure was 6.4 thousand tons of fish and fishery products, and in 2019 it reached 7.6 thousand tons. The main countries that buy Ukrainian fish are: Moldova, Denmark, Georgia, Azerbaijan and Germany. The main export is processed fish products: crab sticks, canned sardines, coleslaw, while sprats or sprats, frozen cod, salmon and other fish.
Effects of probiotic Clostridium Butyrate on Performance and Immunocompetence and Digestive Function of poultry
Authors: Wang Xiaofei , Xu Yanzhao , Fotina Hanna
Published: April 2020

The purpose of our research was to study the effects of dietary addition of Clostridium butyricum (CB) on performance, immunocompetence and digestive function of poultry. Using single factor experiment design, 720 one-day-old and healthy AA broilers were divided into 6 groups with 6 replicates in each group and 20 broilers in each replicate. Broilers in control group were fed a basal diet, while broilers of other experimental group were fed the basal diet supplemented with CB 250 mg/kg, 500 mg/kg, 750 mg/kg, 1000 mg/kg and 1250 mg/kg. The results showed as follows: The 1000mg/mg group had the best effect on immunity enhancement, with the thymus index, spleen index and bursa index increased by 18.38 % (P < 0.05), 16.00 % (P < 0.05) and 8.03 % (P > 0.05) in 1–21 days, and 6.45 % (P < 0.05), 12.92 % (P < 0.05) and 13.94 % (P < 0.05) in 22–49 days. The 1000 mg/kg group and 1250 mg/kg group had the best effect on improving the digestive function, with the VH/CD value increased by 27.56 % (P < 0.05) and 29.56 % (P < 0.05) in 1–21 days, and 29.48 % (P < 0.05) and 30.80 % (P < 0.05) in 22–49 days, with the number of harmful bacteria Escherichia coli and Salmonella decreased significantly (P < 0.05). These results indicated that the addition of CB in diets of broiler can improve the production performance, enhance immunity and improve digestive function, and the optimal dosage is 1000 mg/kg.
The effectiveness of using protein mixed feed in feeding honey bees
Authors: Nedashkivskyi V. M. , Hutsol H. V.
Published: April 2020

The study of effectiveness of the use of protein feeding bees was carried out in the conditions of the apiary ALLC “Volodymyr” in village Shershni Tyvriv district of Vinnytsia oblast. According to the principle of analogous groups were selected bee colonies for the formation of experimental groups. Protein feed was moistened with 50% sugar syrup and filled in the honeycomb. According to the experimental scheme during the preparatory period the bee colonies of the experimental groups II, III and IV were fed a feed mixture in an amount of 25 g per day. According to the experimental scheme during the main period bee colonies were fed a feed mixture of 70 g per day. Accounting of bees brood on the set dates was carried out at the expense of a grid frame every 12 days. Commercial honey was determined by weighing after pumping from each bee colonies separately. Forage honey was determined by weighing the honeycomb and then subtracting the conditional mass of the honeycomb. During the experimental Ukrainian breed bee colonies were involved which they were kept in long hive. Care and maintenance for bee colonies were the same. It was studied the effectiveness of using combined protein feeds in bee feeding. It is proved that in the spring during the harvesting honey use protein feeds (defatted soya flour with soy peptides and pollen) for feeding bees has a positive effect on the brood rearing by bee colonies and the production of honey and wax in the following sequence: defatted soya flour and pollen (50 % + 50 %) defatted soya flour and soy peptides (50 % + 50 %) defatted soya flour (100 %).
The influence of the preparation “Bendamin” on the morphological and biochemical indices of blood of rats in experimental modeling of heart failure
Authors: Varkholiak I. S. , Gutyj B. V.
Published: April 2020

The purpose of this work was to study the influence of “Bendamin” on the morphological and biochemical indices of rat blood in experimental modeling of heart failure. The investigation were performed on white sexually mature young  male-rats of Wistar line  weighing 180–200 g, kept at the standard ration of the institute vivarium of the State Research Institute of Veterinary Preparations and Fodder Additives. To create a model of doxorubicin-induced cardiomyopathy, 24 male rats were selected. Animals were divided into 3 groups of 6 animals in each: control group – intact animals; experimental group E1, in which animals were modeled doxorubicin-induced cardiomyopathy by intraperitoneal injected of doxorubicin at a dose of 2.5 mg/kg 3 times a week for two weeks; experimental group E2, in which animals, after injection of doxorubicin, the preparation “Bendamin” was injected in the dose 20 mg/kg intragastrically. For experimental modeling of heart a decrease in the number of red blood cells was found in the blood of rats of the first experimental group by 34.7 % and hemoglobin level – by 24.2 %, with a simultaneous increase in the average hemoglobin content in one erythrocyte by 16.2 %. Doxorubicin-induced cardiomyopathy in rats of the first experimental group was accompanied by a decrease in leukocyte count by 22.2 %, an increase in uric acid level by almost in 2 times, creatinine by 11.4 %, cholesterol by 61.1 %. In the research of the protein synthesizing function of the liver of rats in experimental modeling of heart failure, a decrease in total protein by 9.6 % was found. These changes were accompanied by a slight decrease in albumin levels and a slight increase in globulin levels. By intoxication with doxorubicin, rats of the first experimental group showed a violation of the functional state of the liver, indicating an increase in the activity of aminotransferases in their blood, namely: AlAT by 34.2 %, AsAT – by 21.7 %, accordingly. Positive action of cardio preparation “Bendamin” on rats organism under conditions of creation of a model of doxorubicin-induced cardiomyopathy was installed, manifested by the normalization of hematological and biochemical parameters, functional status and protein synthesis of the liver.
Resistencias indígenas
Authors: Aparicio Wilhelmi Marco , Varo Barranco Anaís , Sánchez De Jaegher Carolina , El Fakih Rodríguez Fátima , García Ruales Jenny , Mora Navarro Fanny Verónica , Cassú Camps Enric , Rufino Parente Alexis , Duque Santiago R. , Guagnelli Núñez Aldo Armando
Published: April 2020

El 30 i 31 de maig de 2019 es va celebrar la X Edició de la Trobada de la Xarxa Multidisciplinària sobre Pobles Indígenes, amb la temàtica de ́Resistències Indígenes ́, coordinada per Salvador Martí Puig i Marco Aparicio, i organitzat per Daniel Rodríguez, Nila Chávez, María Inés Rivadeneira i Anaïs Varo. La X Trobada EMPI no només es va convocar com una trobada acadèmica, si no que de forma decidida es va pensar per a totes aquelles persones que treballen per aconseguir el ple compliment dels drets dels pobles indígenes, integren o acompanyen els processos de transformació i de lluita dels pobles i nacions indígenes i a els qui defensen el dret a la protesta i denuncien la seva criminalització.
Modified Block-Pulse Functions Scheme for Solve of Two-Dimensional Stochastic Integral Equations
Authors: FALLAHPOUR Mohsen , KHODABİN Morteza
Published: April 2020

In this paper, two-dimensional modified block-pulse functions (2D-MBPFs) method is introduced for approximate solution of 2D-linear stochastic Volterra-Fredholm integral equations so the ordinary and stochastic operrational matrices of integration are utilized to reduce the computation of such equations into some algebraic equations. Convergence analysis of this method is discussed. Finally an illustrative example is given to show the accuracy of the proposed method so the results of it is compared with the block-pulse functions (BPFs) method.
Learning from Royal Shell’s Logistics and Supply Chain Management
Authors: AbdulGhani Gaghman
Published: April 2020

The study is conducted to analysis the supply chain management paying special attention to the logistics. The aim is to understand the impact of logistics on organization performance, also to help in identifying opportunities for cost/time removals and/or value adding along the supply chain. The company chosen for the study is Royal Dutch Shell Plc. As Shell is the one of the big-gest Oil and Gas Company known in the world and one of the leaders of logistic and supply chain management.  Though Shell is working efficiently for providing customers with quality services still there are is-sues with the supply chain which should be taken care of in order to be much better. These factors grouped in Control the Cost, Planning and Risk Management, Suppliers/Owners Relationship Management. Study concluded with some suggestions can be adopted by any organization aiming for better performance in supply chain.
Aritmética e objetos manipuláveis: uma proposta metodológica para os anos iniciais do ensino fundamental
Authors: Frazão Samara Sales , Barroso Maria Cleide da Silva
Published: April 2020

Considerando os resultados obtidos em avaliações em larga escala, realizadas tanto em nível nacional como internacional, Prova Brasil e PISA respectivamente, que apontam dados preocupantes quanto ao desenvolvimento das habilidades pertinentes à matemática, nos inquietamos em investigar quais as possíveis causas para o fracasso escolar. Nesse sentido, lançamos uma luz nas práticas pedagógicas desenvolvidas nos anos iniciais do ensino fundamental, tendo em vista a pouca diversidade dos recursos pedagógicos utilizados em sala, uma vez que predominam o livro e o caderno. Temos como objetivo geral refletir sobre a utilização dos materiais manipuláveis, em especial do material dourado, no processo de ensino e aprendizagem das propriedades do sistema de numeração decimal e, por conseguinte, do cálculo matemático nos anos iniciais do ensino fundamental. Para tanto, a pesquisa está constituída em um estudo teórico-bibliográfico projetando ampliar nossas concepções e possibilitar uma melhor discussão acerca do fenômeno em questão. Após as leituras e reflexões observou-se um consenso entre os autores em relação à importância e os benefícios da utilização dos materiais manipuláveis nas aulas de matemática.