bluuebunny/crossref_metadata_2025 huggingface dataset:
EMOÇÕES A FLOR DA PELE: A RELAÇÃO ENTRE AS FALHAS DO EMPREENDEDOR E OS ASPECTOS AFETIVOS
Authors: DA COSTA EVANGELISTA JULIANE , Nassif Vânia Maria Jorge , Paiva Luis Eduardo Brandão , Dellaquila Alessandra Cassia de Medeiros
Published: November 2023

Objetivo: Esta pesquisa tem como objetivo investigar como os aspectos afetivos dos empreendedores se relacionam com as falhas.
Método/abordagem: O método utilizado é o qualitativo de natureza descritiva e exploratória. A coleta de dados foi realizada por meio de entrevistas com 15 empreendedores brasileiros. Os dados foram categorizados através do software Atlas.ti. Em seguida, foi realizada a análise dos dados, adotou-se o método da análise de conteúdo, considerando a perspectiva de Bardin (2016).
Principais Resultados: Os resultados obtidos variaram de acordo com as vivências e particularidades de cada indivíduo. As emoções dos empreendedores foram identificadas em duas vertentes: (i) os aspectos afetivos podem afetar o empreendedor, levando-o a realizar ações e atitudes ineficazes, resultando em falhas no negócio; e (ii) as consequências e as emoções que o empreendedor carrega após a falha ter ocorrido. Ambas as vertentes apresentaram atenuantes positivos e negativos, variando em intensidade e tempo de duração.
Contribuições teóricas/práticas/sociais: O propósito deste estudo é contribuir para o debate sobre como a afetividade pode afetar os empreendedores e preencher uma lacuna nas evidências existentes. Mais especificamente, este estudo visa retirar o estigma associado à falha como algo que traz apenas consequências negativas para o empreendedor, ajudando a promover um processo de aprendizagem mais efetivo.
Originalidade/relevância: Ao investigar como os aspectos afetivos dos empreendedores se relacionam com as falhas, alinhando os campos do conhecimento do empreendedorismo e da psicologia, este estudo se mostra relevante por oferecer insights que possam ser aplicados tanto no âmbito acadêmico quanto no gerencial, contribuindo para o desenvolvimento do empreendedorismo e o aprimoramento das práticas empreendedoras.
Case Study of Stomatitis Medicamentosa Due to Trigeminal Neuralgia Medication
Authors: Reddy Pavani , C Ganesh
Published: November 2023

Our study aim is to characterize and assess the case of Stomatitis medicamentosa in a patient who developed manyoral ulcers after using Carbamazepine for the treatment of Trigeminal Neuralgia of a 35-year-old female patient with a medicalhistory of hypertension for the past ten years and under medication. The patient also gave a history of electric shock-like painon the left side of the face for the past month and was prescribed Tegretol 100mg (Carbamazepine) twice daily. After taking thismedication, the patient suffered several mouth ulcers. The patient was asked to stop taking this medication and asked to takeoral antihistamines and systemic Gabapentin steroids for one month. After one week, the patient heals completely from thelesions. Burning sensation with altered taste sensation and difficulty while swallowing are common patient complaints. Mouthopening was restricted and painful. The skin test (prick test) is done, which shows red, papular, or vesicular reactions. Earlyidentification of the lesion and prompt withdrawal of the offending drug are key for successful management, and the drug can bereplaced with another drug of the same efficacy. Thus, adverse drug reactions can be minimised by asking the patient aboutallergy to any drug or food while writing a prescription, and the patient should be informed and familiarised with the drugpatient the patient is allergic.
Simulación numérica de la producción de hollín en una llama laminar de difusión axisimétrica de propano
Authors: Salazar-Navarro Adalberto Rafael
Published: November 2023

En este trabajo se realiza el estudio computacional de la formación de hollín para una llama de propano. Estas simulaciones, serealizaron teniendo en cuenta el efecto del uso de parámetros como, la velocidad del flujo y el flujo masico por unidad de área, parala predicción de la formación de hollín. También se tienen en cuenta parámetros como la altura de llama y la temperatura. En elpresente artículo se utiliza la herramienta computacional Fire Dynamics Simulator (FDS) para observar el comportamiento de laproducción de hollín en una llama laminar de difusión de propano (C3H8). En particular, se comparan los resultados de este softwarecon (a) datos experimentales presentados dentro de la literatura y (b) con las aproximaciones Large Eddy Simulation (LES) y DirectNumerical Simulation (DNS), las cuales se emplean para predecir parámetros como, la producción de hollín, altura de llama y latemperatura de llama alcanzada. Los resultados obtenidos muestran un buen comportamiento frente a los resultados experimentales.
Estratégia de Difusão Agressiva para Aumentar a Vazão do Algoritmo de Consenso HyperPaxos
Authors: Pereira Djenifer R. , Kiotheka Fernando M. , Duarte Jr Elias P.
Published: November 2023

Algoritmos de consenso distribuído são essenciais para sistemas de armazenamento, bancos de dados, controle de acesso e orquestração de aplicações em nuvem. Este trabalho apresenta uma estratégia para melhorar a vazão do algoritmo HyperPaxos em termos de decisões por segundo. O algoritmo HyperPaxos é uma versão hierárquica de um dos principais algoritmos de consenso, o Paxos. O HyperPaxos é baseado na topologia virtual hierárquica vCube, que apresenta diversas propriedades logarítmicas. Os acceptors são organizados em clusters e os proposers executam as duas fases do Paxos escolhendo um acceptor dito difusor. O difusor é responsável por retransmitir as mensagens para os demais acceptors sobre o vCube. Neste trabalho, propomos que o difusor adote uma estratégia de difusão agressiva para transmitir, de uma só vez, as mensagens para uma maioria de acceptors paralelamente. A estratégia proposta foi implementada e comparada à versão original. Resultados obtidos mostram o desempenho superior da estratégia proposta em todos os cenários testados.
Brute force prey metabarcoding to explore the diets of small invertebrates
Authors: Flo Snorre , Vader Anna , Præbel Kim
Published: November 2023

1. Prey metabarcoding has become a popular tool in molecular ecology for
resolving trophic interactions at high resolution, from various sample
types and animals. To date, most predator-prey studies of small-sized
animals (<1 mm) have met the problem of overabundant predator
DNA in dietary samples by adding blocking primers/peptide nucleic acids.
These primers aim to limit the PCR amplification and detection of the
predator DNA but may introduce bias to the prey composition identified
by interacting with sequences that are similar to those of the predator.
2. Here we demonstrate the use of an alternative method to explore the
prey of small marine copepods using whole-body DNA extracts and deep,
brute force metabarcoding of an 18S rDNA fragment. 3. After processing
and curating raw data from two sequencing runs of varying depth (0.4 and
5.4 billion raw reads), we isolated 1.3 and 52.2 million prey reads,
with average depths of ~15 900 and ~120
000 prey reads per copepod individual, respectively. While data from
both sequencing runs were sufficient to distinguish dietary compositions
from disparate seasons, locations and copepod species, greater
sequencing depth led to better separation of clusters. 4. As computation
and sequencing are becoming ever more powerful and affordable, we expect
the brute force approach to become a general standard for prey
metabarcoding, as it offers a simple and affordable solution to
consumers that are impractical to dissect or unknown to science.
Tree mycorrhizal associations determine how biodiversity, large trees, and environmental factors drive aboveground carbon stock in temperate forests
Authors: Yue Chen , Mao Zikun , Myers Jonathan A. , Yu jinghua , Wang Xugao
Published: November 2023

Experimental and observational studies have elucidated that an
amalgamation of biotic (e.g., biodiversity, large trees) and abiotic
factors (e.g., climate, soil) jointly determine tree aboveground carbon
stock within forest ecosystems. Yet, a pivotal factor potentially
influencing these carbon repositories might be the specific tree
mycorrhizal associations, especially given that ectomycorrhizal (EM)
tree species frequently comprise more large-sized trees, translating to
an augmented carbon reserve, as opposed to arbuscular mycorrhizal (AM)
counterpart. However, how biotic and abiotic factors determine forest
carbon through regulating AM vs. EM tree carbon stock is still elusive
across large regions. Here, we examined a forest inventory data
consisting of over 90,000 trees from 631 forest plots (30m × 30m each).
Our objective was to explore how biodiversity (i.e., species diversity
and ecological uniqueness), large trees (top 1% tree diameters), and
environmental factors (e.g., climate and soil nutrients) differently
regulate AM and EM, and thus, total tree aboveground carbon stock of
temperate forests in northeast China. Our findings illuminated that
large trees had consistent enhancement effect on AM and EM tree carbon
repositories. However, the effects of biodiversity and environmental
factors on carbon stock were opposite between AM and EM trees.
Specifically, the two components of biodiversity were positively
associated with AM tree carbon stock while negatively associated with EM
tree carbon stock. Environment heterogeneity (i.e. mean annual
temperature and soil nutrients) also exhibited contrasting impacts on AM
and EM tree carbon stock. Consequently, when integrating AM and EM tree
carbon stock into total carbon stock, the consistent effect of large
trees on AM vs. EM trees was strengthened and most important, while the
opposite effect of biodiversity or environment factors was diluted. In
summary, this study emphasized a mycorrhizal viewpoint to better
understand the determinants of overarching aboveground carbon profile
across regional forests.
Research on the Dynamic Mechanical Properties and Energy Dissipation Rules of Gradient Materials
Authors: Zhang Yuantong , Renshu Yang , Jun Chen , Li Chengxiao , Boyang Zhai , Rui Zhu
Published: November 2023

In engineering practice, the strength of layered rock often changes in a
gradient manner, and the failure mode and strength under dynamic loads
of strength gradient composites are important indicators for evaluating
their mechanical properties. The Split Hopkinson Pressure Bar (SHPB)
technology can measure the material’s constitutive relationship under a
fixed strain rate, which is one of the basic means of dynamic mechanics
testing. This article uses the SHPB device to conduct dynamic
compression tests on sandstone gradient rock, studies its dynamic
mechanical properties, and combines the DIC method to study the
deformation field and strain field of the test piece, analyzing the
dynamic failure mode of strength gradient composites under different
impact speeds. By introducing the concept of equivalent wave impedance,
it systematically expounds the impact of the impedance ratio in gradient
composites and the length of incident waves on the transmission
coefficient.
Could refuges from human disturbance stem the decline of Capercaillie in Scotland?
Authors: Geary Matthew , Moss Robert , Kortland Kenny
Published: November 2023

Capercaillie in Scotland have declined in number and contracted in range
since the 1970s, most remaining in Strathspey on the northwest flank of
the Cairngorm mountains. Strathspey, however, is popular for recreation
and suffers anthropogenic disturbance from visitors and their use of new
forest tracks and remote, off-track areas. Disturbance reduces the area
of forest available to Capercaillie. Refuge areas wherein the creation
of new tracks is not allowed, and in which recreation is not encouraged,
are a management option that might mitigate such effects. We simulate
this possibility for the area covered by Forest and Land Scotland’s
Strathspey Land Management Plan. Spatially explicit, stage-based matrix
models assessed the potential of protecting this population with refuges
under ‘optimistic’, ‘central’ and ‘pessimistic’ scenarios based on
observed demographic data. Fifteen potential refuges comprised
less-disturbed areas of forest still used by Capercaillie. We simulated
population growth using combinations of 1, 3, 5, 7, 10, 12 and the full
complement of 15 refuge areas. An increasing Capercaillie population
could be sustained by a network of refuges, but refuges could not arrest
a wider population decline due to causes other than disturbance. This
suggests that refuges could play a role in mitigating the increasingly
damaging effects of disturbance on Capercaillie in the Strathspey LMP
but that the birds’ long-term prospects will depend upon improving their
performance more widely.
Listening to life: Sonification for enhancing discovery in biological research
Authors: Braun Rhea , Tfirn Maxwell , Ford Roseanne
Published: November 2023

Sonification, or the practice of generating sound from data, is a
promising alternative or complement to data visualization for exploring
research questions in the life sciences. Expressing or communicating
data in the form of sound rather than graphs, tables, or renderings can
provide a secondary information source for multitasking or remote
monitoring purposes or make data accessible when visualizations cannot
be used. While popular in astronomy, neuroscience, and geophysics as a
technique for data exploration and communication, its potential in the
biological and biotechnological sciences has not been fully explored. In
this review, we introduce sonification as a concept, some examples of
how sonification has been used to address areas of interest in biology,
and the history of the technique. We then highlight a selection of
biology-related publications that involve sonifications of DNA datasets
and protein datasets, sonifications for data collection and
interpretation, and sonifications aimed to improve science communication
and accessibility. Through this review, we aim to show how sonification
has been used both as a discovery tool and a communication tool and to
inspire more life-science researchers to incorporate sonification into
their own studies.
India-Asia slowing convergence rate controls on the Cenozoic Himalaya-Tibetan tectonics
Authors: Knight Ben , Capitanio Fabio Antonio , Weinberg Roberto F. , Zilio Luca Dal
Published: November 2023

The Cenozoic evolution of the Himalaya-Tibet Plateau, dictated by the
India-Asia convergence, remains a subject of substantial ambiguity.
Here, a thermo-mechanical model is used to show the critical controls of
decelerating convergence on the formation and stabilization of
distinctive tectonic structures during prolonged collision. At high
constant convergence rates, similar to the late Paleogene India-Asia
motions, the lower plate crust is injected beneath the overriding crust,
uplifting a plateau, first, then is exhumed towards the orogeny front.
Conversely, low constant convergence rates, similar to the Neogene
India-Asia motions, induce crustal thickening and plateau formation
without underplating or exhumation of incoming crust. Strikingly, models
simulating the decelerating India-Asia convergence history portray a
dynamic evolution, highlighting the transitory nature of features under
decreasing convergence, as the orogen shifts to a new equilibrium. In
the transitional phase, the slowing of convergence decreases basal
shearing and compression, leading to extension and heating in the orogen
interiors. This allows diapiric ascent of buried crust and plateau
collapse, as accretion migrates to a frontal fold-and-thrust belt. The
models provide insights into the multi-stage evolution of the long-lived
Himalayan-Tibetan orogeny, from fast early growth of the Tibetan
Plateau, through its transient destabilisation and late-stage internal
extension, behind the expanding Himalayan belt.
Nearshore flow dynamics over shore-oblique bathymetric features during storm wave conditions
Authors: Szczyrba Laura , Mulligan Ryan , Pufahl Peir Kenneth , Humberston Josh L , McNinch Jesse
Published: November 2023

Shore-oblique bathymetric features occur around the world and have been
statistically correlated with enhanced shoreline retreat on sandy
beaches. However, the physical mechanisms that explain a causal
relationship are not well understood. In this study, radar remote
sensing observations and results from a phase-resolved numerical model
explore how complex morphology alters nearshore hydrodynamics.
Observations at selected times during high-energy storm events as well
as a suite of idealized simulations indicate that shore-oblique features
induce strong spatial variations in the water surface elevation and wave
breaking patterns. Re-emergent offshore flows and longshore current
accelerations occur near the apex of the oblique nearshore features. The
results suggest that complex bathymetric morphology exerts a powerful
control on nearshore hydrodynamics and increases the potential for
enhanced cross-shore and alongshore sediment transport, thus
contributing to localized erosional zones.
Ventilation of the Arabian Sea Oxygen Minimum Zone by Persian Gulf Water
Authors: Font Estel , Swart Sebastiaan , Bruss Gerd , Sheehan Peter M. F. , Heywood Karen J. , Queste Bastien Yves
Published: November 2023

Dense overflows from marginal seas are critical pathways of oxygen
supply to the Arabian Sea Oxygen Minimum Zone (OMZ), yet these remain
inadequately understood. Climate models struggle to accurately reproduce
the observed extent and intensity of the Arabian Sea OMZ due to their
limited ability to capture processes smaller than their grid scale, such
as dense overflows. Multi-month repeated sections by underwater gliders
off the coast of Oman resolve the contribution of dense Persian Gulf
Water (PGW) outflow to oxygen supply within the Arabian Sea OMZ. We
characterize PGW properties, seasonality, transport and mixing
mechanisms to explain local processes influencing water mass
transformation and oxygen fluxes into the OMZ. Atmospheric forcing at
the source region and eddy mesoscale activity in the Gulf of Oman
control spatiotemporal variability of PGW as it flows along the shelf of
the northern Omani coast. Subseasonally, it is modulated by stirring and
shear-driven mixing driven by eddy-topography interactions. The oxygen
transport from PGW to the OMZ is estimated to be 1.3 Tmol
yr over the observational period, with dramatic
inter- and intra-annual variability (±1.6 Tmol yr).
We show that this oxygen is supplied to the interior of the OMZ through
the combined action of double-diffusive and shear-driven mixing.
Intermittent shear-driven mixing enhances double-diffusive processes,
with mechanical shear conditions (Ri<0.25) prevailing 14% of
the time at the oxycline. These findings enhance our understanding of
fine-scale processes influencing oxygen dynamics within the OMZ that can
provide insights for improved modeling and prediction efforts.
Wavelet Analysis for Automatic Detection of Pi-2 Pulsations during Substorm Onset Along the 210$^{\circ}$ Magnetic Meridian
Authors: Omondi stephen Owino , Yoshikawa Akimasa , Uozumi Teiji , Obana Yuki , Hayashi Moe , Mahrous Ayman Mohamed
Published: November 2023

Ground Pi-2 pulsations comprise superpositions of various modal
components of shear and fast Alfven waves, field line resonance, and
plasmaspheric resonances. These complex waveforms, hard to resolve with
Fourier transforms are successfully characterized by wavelet techniques.
Wavelet detection employs decomposition and reconstruction modes to
characterize time-frequency components. Hence, suitable for the
examination of the locality and complexity of natural signal patterns.
The current study presents the automatic detection of Pi-2 pulsations
using Daubechies and Morlet wavelet transforms. In the study, distinct
Pi-2 events from CPMN stations along 210${^\circ}$
magnetic meridian were detected. Global Pi-2 pulsations with harmonious
H oscillations and discrete D bays in the sub-aurora zone suggest a
common source with diverse tunneling paths. Scalograms of Pi-2
undulations of the frequency band of 6.7-22 mHz were observed despite
different kinds of Pi-2s. Auroral Pi-2s were highly localized in local
time with clear H and D bays, implying magnetospheric-ionospheric
current couplings. Latitudinal and longitudinal Pi-2 propagations are
exemplified by 180${^\circ}$ phase-shift
(polarization) in EWA and group delay in the mid-latitudes of the
northern hemisphere. Overall, Pi-2 wave power from high to low latitudes
declined with peak amplitudes of 15 nT to less than 1 nT, respectively.
Finally, external influences from sea currents causing signal
attenuation due to the station’s proximity to the sea were also
identified. To conclude, the accuracy and efficiency of wavelet analysis
with no computation hassle render it a valuable tool for the study of
space events in the magnetospheric community.
Multi-decadal trends of low clouds at the Tropical Montane Cloud Forests
Authors: Q. J. Antonio Guzmán , Hamann Hendrik F. , Sanchez-Azofeifa G. Arturo
Published: November 2023

Clouds are critical to the biodiversity and function of Tropical Montane
Cloud Forests (TMCF). These ecosystems provide vital services to
humanity and are considered hotspots of endemism, given that the number
of species is restricted to their microclimates. Cloudiness (e.g., the
fraction of low-clouds) in these ecosystems is projected to decline
owing to global warming, but recent temporal trends remain unclear.
Here, we evaluated trends in low-cloud fractions (CF) and other
Essential Climatic Variables (ECV) (e.g., surface temperature, pressure,
soil moisture, and precipitation) for 521 sites worldwide with TMFCs
from 1997 to 2020. Thus, we hypothesize that recent traces of global
warming over the last few decades have led to decreases in low-cloud
cover on TMCFs. The previous study was also evaluated globally and among
biogeographic realms to identify regional trends. We computed trends by
aggregating hourly observations from ERA5 reanalysis and CHIRPS into
annual averages and then used linear regressions to calculate slopes
(i.e., rate of change) (Δ, year). Our results
suggest that CF trends at the TMCFs range between -64.7
×10 and 51.4 ×10 CF
year, revealing that 70% of the assessed sites have
experienced reductions in CF. Declines in low-clouds in these ecosystems
are 253% more severe than tropical landmasses when peak values of
density distribution are compared (TMCFs: -7.8 ×10CF
year; tropical landmasses -2.3
×10 CF year). Despite this, CF
trends tend to differ among biogeographic realms, as those TMCFs from
the Neotropics and Indomalayan realms have the most pronounced declines.
Decreases in CF were also associated with increases in surface
temperature and pressure and decreases in soil moisture, revealing that
the TMCF’s climate is changing to warmer environments. These climatic
shifts may represent a fingerprint of global change on TMCFs,
highlighting a current threat to species and essential ecosystem
services that these ecosystems provide.
METTL3-mediated m6A Methylation Controls Pancreatic Bipotent Progenitor Fate and Islet FormationUntitled Item
Authors: Sun Jiajun , Wang Yanqiu , Fu Hui , Kang Fuyun , Song Jiaxi , Xu Min , Ning Guang , Wang Jian , Wang Weiqing , Wang Qidi
Published: November 2023

The important role of m6A RNA modification on β cell function has been established, yet how it regulates pancreas development and endocrine differentiation remains unknown. Here, we generated transgenic mice lacking RNA methyltransferase-like 3 (Mettl3) specifically in Pdx1+ pancreatic progenitor cells and found the mutant mice developed hyperglycemia and hypo-insulinemia at 2 weeks of age, with atrophic pancreas, reduced islet mass and abnormal increase in duct formation. At E15.5, Mettl3 deletion caused a significant loss of Ngn3+ endocrine progenitor cells, which was accompanied by increased Sox9+ duct precursor cells. We identified histone deacetylase 1(Hdac1) as the critical direct m6A target in bipotent progenitor, whose degeneration caused abnormal activation of Wnt/Notch signaling pathway and blocked endocrine differentiation. This transformation could be manipulated in embryonic pancreas culture in vitro through the regulation of the axis of Mettl3-Hdac1-Wnt/Notch signaling. Our finding that Mettl3 determines endocrine lineage through modulating Hdac1 activity during the transition of bipotent progenitor might help in the development of targeted endocrine cell protocols for diabetes treatment.
The cemetery of the Trzciniec Cultural Circle community in Łubna in light of radiocarbon chronology (AMS)
Authors: Makarowicz Przemysław , Muzolf Przemysław , Romaniszyn Jan
Published: November 2023

The barrow cemetery in Łubna (Łubna-Jakusy), Poland, excavated shortly after World War II , is one of the best-known necropolises in the western area of the Trzciniec Cultural Circle. During the archaeological research conducted by K. Jażdżewski, up to 27 mounds wereexcavated. In this article, the authors present and specify the absolute chronology of this site. Thanks to a search in the museum storerooms, it was possible to obtain osteological material, which was subsequently dated in the Poznań Radiocarbon Laboratory using the AM S method. These absolute dates combined with the results of a study of the archaeological material allowed the chronology of almost half of the excavated barrows to be defined. The dates obtained thanks to modelling functions answer the question about the timeframe the necropolis was in use. Additionally, the authors present a probable scenario for the development of the cemetery in Łubna, outlining the direction of expansion and characterizing its spatial arrangement.
Wczesnośredniowieczne bursztynowe krzyżyki z terenu Pomorza na tle porównawczym. Materiały i problemy interpretacyjne
Authors: Szczepanik Paweł
Published: November 2023

This paper presents early medieval amber cross pendants that display a great degree of diversity not only concerning form and morphology but also with regard to chronology and – as we assume – functionality, with the pendants examined herein sharing one common denominator: the raw material from which are made. This paper analyses amber artefacts discovered in Pomerania, shown in a broad comparative context. Thus, the research objectives undertaken are twofold: first, to present the sources of the relevant materials, which are formally, chronologically, and contextually diverse, and second, to point out the main interpretative problems relating to the possibility of deciphering their original meanings and functions.
Prof. dr hab. Jerzy Kmieciński (8 października 1927 – 5 grudnia 2022)
Authors: Olędzki Marek , Klonowski Michał
Published: November 2023

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Using novel data linkage of biobank data with administrative health data to inform genomic analysis for future precision medicine treatment of congenital heart disease
Authors: Lain Samantha J. , Blue Gillian , O’Malley Bridget , Winlaw David , Sholler Gary , Dunwoodie Sally , Nassar Natasha , The Congenital Heart Disease Synergy Study group
Published: November 2023

IntroductionContemporary care of congenital heart disease (CHD) is largely standardised, however there is heterogeneity in post-surgical outcomes that may be explained by genetic variation. Data linkage between a CHD biobank and routinely collected administrative datasets is a novel method to identify outcomes to explore the impact of genetic variation.
ObjectiveUse data linkage to identify and validate patient outcomes following surgical treatment for CHD.
MethodsData linkage between clinical and biobank data of children born from 2001-2014 that had a procedure for CHD in New South Wales, Australia, with hospital discharge data, education and death data. The children were grouped according to CHD lesion type and age at first cardiac surgery. Children in each `lesion/age at surgery group' were classified into 'favourable' and 'unfavourable' cardiovascular outcome groups based on variables identified in linked administrative data including; total time in intensive care, total length of stay in hospital, and mechanical ventilation time up to 5 years following the date of the first cardiac surgery. A blind medical record audit of 200 randomly chosen children from 'favourable' and 'unfavourable' outcome groups was performed to validate the outcome groups.
ResultsOf the 1872 children in the dataset that linked to hospital or death data, 483 were identified with a `favourable' cardiovascular outcome and 484 were identified as having a 'unfavourable' cardiovascular outcome. The medical record audit found concordant outcome groups for 182/192 records (95%) compared to the outcome groups categorized using the linked data.
ConclusionsThe linkage of a curated biobank dataset with routinely collected administrative data is a reliable method to identify outcomes to facilitate a large-scale study to examine genetic variance. These genetic hallmarks could be used to identify patients who are at risk of unfavourable cardiovascular outcomes, to inform strategies for prevention and changes in clinical care.
Behind the Scenes of the Mind: an Attempt to Conceptualize the Types of Philosophizing Subjects
Authors:   Kryvyi Rih State Pedagogical University, Panafidina Oksana
Published: November 2023

The article examines the metaphilosophical issue of the philosophizing subjects. The transcendental argument addresses the inquiry into what enables the variety of existing philosophizing practices. A conceptual model of philosophizing subjects is developed using the reconstructed Kantian model of the mind. Following this model, the article discusses marginal and mainstream types. The former comprises epigones and skeptics, while the latter encompasses dogmatic metaphysicians, scientific rationalists, relativists, and critical rationalists. In the modeling of philosopher-innovator types, the concept of maximalist and minimalist philosophies by Tatarkiewicz is also incorporated.
Foreword to the Ukrainian Translation of Isaiah Berlin's Article "The Purpose of Philosophy"
Authors:   Zaporizhzhia State Medical University, Sepetyi Dmytro
Published: November 2023

The foreword focuses on the life of Isaiah Berlin, his interests, as well as the article “The Purpose of Philosophy”, which is translated into Ukrainian for the first time. Isaiah Berlin's metaphilosophical reflections on philosophy are important for understanding what is the place of philosophy in the system of sciences, what tasks philosophy can solve. This article also explains the value of philosophy for society and man.
Osobennosti ekspressii CD163+ i HLA-DR+ na monocitah krovi pri rake molochnoj zhelezy
Authors: Патышева М. Р. , Стахеева М. Н. , Григорьева Е. С. , Тарабановская Н. А. , Брагина О. Д. , Кжышковска Ю. Г. , Чердынцева Н. В.
Published: November 2023

Cirkuliruyushchie monocity — znachimye uchastniki patogeneza opuholevogo rosta. Pokazano, chto v krovi bol'nyh rakom molochnoj zhelezy nablyudayutsya osobennosti populyacij monocitov, ekspressiruyushchih receptory endocitoza, libo komponentov glavnogo kompleksa gistosovmestimosti. Cel'yu dannoj raboty bylo provedenie analiza vzaimosvyazi parametrov opuholi i citokinovogo profilya krovi s populyacionnym sostavom cirkuliruyushchih monocitov bol'nyh lokalizovannymi i mestno-rasprostranennymi formami raka molochnoj zhelezy. V issledovanii bylo pokazano, chto fenotipicheskie harakteristiki cirkuliruyushchih monocitov vzaimosvyazany s kliniko-morfologicheskimi osobennostyami opuholevogo processa. Soderzhanie populyacij s fenotipom CD14+CD16++CD163+ i CD14++CD16+CD163+ imelo polozhitel'nuyu korrelyaciyu so stadiej zabolevaniya, v to vremya kak bol'shij razmer pervichnogo opuholevogo uzla associirovan s bolee nizkim soderzhaniem CD14+CD16++-monocitov. U bol'nyh RMZH uvelicheno soderzhanie IL8 i MSR-1 v syvorotke krovi. Vysokij uroven' soderzhaniya IL6 u bol'nyh RMZH associirovan so snizheniem doli CD14++CD16-HLADR+ monocitov, CD14+CD16++HLA-DR+-monocitov i CD14++CD16-SD163+-monocitov. Takim obrazom, CD163+ i HLA-DR+-monocity svyazany s klinikomorfologicheskimi parametrami i urovnem citokinov krovi, chto svidetel'stvuet o vovlechenii dannyh populyacij v progressiyu raka molochnoj zhelezy i govorit o celesoobraznosti dal'nejshih issledovanij dlya translyacii poluchennyh rezul'tatov v klinicheskuyu praktiku.
De ir y venir: variantes textuales en la obra de Olvido García Valdés
Authors: García-González Ariana
Published: November 2023

La publicación de Esa polilla que delante de mí revolotea en 2008 y recopilaciones posteriores evidencia que los poemas de Olvido García Valdés no se han desprendido por completo de la mano de su autora, sino que están sujetos a un proceso de relectura que puede implicar modificaciones en los mismos, o incluso su desaparición. El objetivo de este artículo consiste en examinar dicho proceso y mostrar algunas de las intervenciones llevadas a cabo en los textos. Esta tarea hace aflorar dos operaciones consustanciales a esta escritura y determinantes para la comprensión de su poética: la depuración y la precisión.
“¿Quién hablará cuando callemos?”: compromiso y memoria en La voz perdida / La veu perduda de Angelina Gatell
Authors: Lozano Marín Laura
Published: November 2023

En el presente artículo se propone analizar el poemario bilingüe de la escritora catalana Angelina Gatell publicado de manera póstuma en 2017 y titulado La voz perdida / La veu perduda.

El objetivo fundamental del trabajo es estudiar la presencia y la utilización del compromiso social y la memoria este último libro de poemas de la autora, para cuyo análisis se ha recurrido también a la autobiografía Memorias y desmemorias (2012) y diferentes entrevistas en las que la escritora plasmó su testimonio.
La luz sepultada de Irene Vallejo: una exploración del espacio del miedo, Zaragoza verano 1936
Authors: Serrano Asenjo Enrique
Published: November 2023

El artículo analiza la primera novela de Irene Vallejo, La luz sepultada (2011). Para ello se inserta la obra, situada en Zaragoza en el verano de 1936, dentro del patrón narrativo de la reparación de las memorias marginadas en relación con la Guerra Civil. El método de trabajo consiste en cartografiar los espacios por los que transitan unos personajes cargados de miedo: el ámbito urbano, sometido a cambios radicales por la extensión de la violencia a partir del 18 de julio; y la casa de la familia protagonista, de ideología republicana, domicilio paulatinamente invadido por la tensión exterior y, por fin, perdido por sus habitantes, tras el fusilamiento del padre.
PEMANFAATAN LIMBAH KULIT KOPI DAN PRAKTIK PEMBUATAN SABUN CASCARA KOPI
Authors: Widyasanti Asri , Muharram Alifiansyah
Published: November 2023

Kopi (Coffea sp.) merupakan komoditas perkebunan yang banyak dibudidayakan di Indonesia. Dusun Cikoneng Babakan, Desa Cibiru Wetan merupakan salah satu wilayah yang memiliki banyak perkebunan kopi rakyat yang sudah dikenal baik oleh masyarakat dengan nama kopi manglayang. Proses pengolahan buah kopi menghasilkan kulit buah kopi yang berlimpah dan belum termanfaatkan dengan optimal. Maka dari itu, diperlukan upaya untuk mengurangi limbah kulit kopi salah satu adalah dengan memanfaatkan limbah kulit buah kopi menjadi produk yang memiliki nilai tambah tinggi. Tujuan pengabdian kepada masyarakat adalah memberikan penyuluhan dan praktik mengenai pemanfaatan limbah kulit kopi menjadi sabun ‘Casa soap”, sehingga sabun ini dapat menjadi produk unggulan atau souvenir khas Cibiru Wetan. Metode PPM yang digunakan adalah pendekatan partisipatori. Dari hasil kegiatan yang telah dilakukan dapat ditarik kesimpulan bahwa: (1) Kegiatan PKM ini dapat memberikan pengetahuan dan ketrampilan masyarakat untuk mengolah limbah kulit kopi menjadi sabun; (2) Peserta pelatihan  terutama kelompok ibu-ibu PKK mengikuti praktik pembuatan sabun dengan antusias. Praktik pembuatan produk ini juga memberikan motivasi usaha bagi peserta pelatihan untuk mengembangkan produk lebih lanjut dengan bekerjasama dengan Badan Usaha Milik Desa (Bumdes) Desa Cibiru Wetan.  Rekomendasi sebagai tindak lanjut kegiatan yaitu pengrajin sabun Desa Cibiru Wetan sebaiknya terus bekerjasama dengan Universitas Padjadjaran dalam bentuk desa binaan sehingga pendampingan, monitoring kualitas produk akhir, serta inovasi produk dapat terus dilakukan.
PENDAMPINGAN PENYUSUNAN LAPORAN KEUANGAN UMKM GEDHANG NUGGET MALANG
Authors: Cahyadi Rino Tam , Lembut Putu Indrajaya , Oktariani Fitri , Pratama Bagas Brian
Published: November 2023

Gedhang Nugget merupakan usaha mikro, kecil, dan menengah (UMKM) yang bergerak dalam industri food and beverages sejak beberapa tahun terakhir. Dalam perjalanannya, usaha tersebut masih belum sepenuhnya menerapkan sistem keuangan akuntansi secara tepat, dan yang paling krusial adalah dari segi pencatatan. Untuk itu, pengabdian masyarakat ditujukan untuk membantu Gedhang Nugget dalam memperbaiki pencatatan keuangannya. Metode pelaksanaan yang digunakan oleh peneliti merupakan metode kualitatif berupa wawancara dan pengamatan langsung dengan data primer terhadap Gedhang Nugget. Selama proses pengabdian, penulis memperoleh informasi dan data yang dibutuhkan melalui pemilik usaha dan pihak yang terlibat langsung dalam operasi. Output dari pengabdian ini adalah pembuatan template Microsoft Excel untuk pencatatan keuangan. Seperti yang diharapkan, keberadaan template yang telah diberi formula dan dihubungkan berperan dalam membantu Gedhang Nugget memantau jumlah penjualannya dan labanya baik secara bulanan maupun tahunan.
Educación comparada o juegos de poder epistemológicos para dominar el mundo
Authors: Tröhler Daniel
Published: November 2023

Este artículo sostiene que los mundos que ha explorado y explora la educación comparada se caracterizan por tres patrones políticos. El primero y más antiguo es el Estado nación competitivo como punto de partida de la comparación, un Estado educacionalizado, cuya fuerza relativa global en economía y su destreza militar se atribuyen al sistema educativo. El segundo patrón, fácilmente visible en la Guerra Fría, es la idea de una progresión casi estandarizada, vinculada al poder económico, militar y, por tanto, geopolítico. Y el patrón contemporáneo es que este nexo entre potencia mundial y educación puede desglosarse en pruebas comparadas de rendimiento escolar (por ejemplo, PISA) a través de las cuales las necesidades de reforma se formulan (casi automáticamente) en el ámbito local y en otros lugares. Si este análisis y su historia -que se ilustran a continuación- son siquiera aproximadamente exactos, la “educación comparada” debería replantearse algunos de sus supuestos básicos.
Meio ambiente
Authors: Krawczyk Ana Carolina de Deus Bueno , Silva Merieli de Melo da , Rosa Jonathan , Gemelli Emanuelli , Ribeiro Marcos Otávio , Bettim Franciele Lima , Assis Helena Cristina da Silva de
Published: November 2023

Os rios são sistemas aquáticos integrados que estão sujeitos a ações abióticas e bióticas. Quando um rio sofre alterações, isso acarreta mudança no fluxo natural de nutrientes e sedimentos. Somado a isso, a utilização de organofosforados em monocultivos próximos a córregos e rios, pode culminar na sua contaminação. Alterações físicas no leito do rio, somado a contaminação através de substâncias com potencial mutagênico, podem gerar efeitos deletérios e acumulativos em organismos de ecossistemas aquáticos. Portanto, o estudo de monitoramento de ecossistemas aquáticos se faz necessário e pertinente. Diante o exposto o presente trabalho objetivou avaliar os possíveis efeitos ecotoxicológicos, em Astyanax bifasciatus. Espécie endêmica de peixe da região Sul do Brasil. Os peixes foram coletados em pontos com diferentes graus de atividade antrópica na bacia do médio Iguaçu-SC. Foi utilizada a metodologia de análise de alterações nucleares (micronúcleo), e atividade da enzima acetilcolinesterase (AChE). Os resultados de nosso trabalho apontaram que nos três pontos de amostragem, os peixes exibiram anomalias micronucleares. Os testes de atividade da enzima acetilcolinesterase apontaram diferenças de sua atividade quando comparada entre os grupos coletados em diferentes pontos, Rio Timbó-SC e Rio Pintado-SC. Nossos resultados reforçam a hipótese que sistemas hídricos que recebem efluentes urbanos não tratados, combinados com possíveis agentes xenobiontes oriundos de monocultivos próximos e alterações ambientais, podem acarretar alterações celulares em nível nuclear/enzimático. Portanto, o monitoramento constante dos ecossistemas aquáticos, se faz cada vez mais pertinente, frente aos desafios contemporâneos em manter o equilíbrio entre a atividade antrópica e a preservação dos recursos naturais.
Palavras-chave: Astyanax bifasciatus; micronúcleo; acetilcolinesterase; alterações.
A pénzügyi tudatosság és a generációs hovatartozás hatása a magyarok megtakarításképzésére
Authors: Csiszárik-Kocsir Ágnes
Published: November 2023

A XXI. század számos változást hozott az életünkbe. Soha nem látott léptéket öltött a digitalizáció és az információáramlás, mely számos előnnyel és hátránnyal járt. A létezésünket minden percben megrohanó információ dömping, a reklámok hada, a döntéseinket befolyásoló üzenetek folyamatos készenlétre kényszerítenek minket. Ebben a felgyorsult világában meg kellett tanulnunk azt, hogy a bizonytalanság állandó, és egyre váratlanabb helyzetekben kell szembe néznünk az élet minden frontján. Ez a bizonytalanság kiterjed nemcsak a jövedelmi pozíciónkra, hanem a munkahelyünkre, egzisztenciánkra is. A globális konfliktushelyzetek pedig csak tovább erősítik ezt a bizonytalansági érzetet. A bizonytalan helyzetekben az egyének és szervezetek alapvető célja a biztonságra törekvés, melyet a rendelkezésre álló eszközök mentén próbálnak elérni. Nincs ez másképp a pénzügyeink tekintetében sem. A megtakarítások célja éppen az, hogy védőhálót képezzen a váratlan, előre nem látható helyzetekre, szituációkra egyéni, nemzeti és nemzetgazdasági szinten egyaránt. Azon nemzetek, amelyek magas megtakarítási rátával rendelkeztek mindig többet tudtak fordítani a beruházásokra, így magasabb gazdasági növekedéssel büszkélkedhettek. A megtakarítások, a kincsképző funkciójukból kiindulva segítenek abban, hogy a hirtelen jött váratlan helyzeteket kezelni lehessen. A megtakarítások napjainkban a klasszikus biztonsági funkción messze túlmutatnak. A fogyasztói társadalomban, a kínálat bősége mellett a jövőbeli fogyasztás zálogát is jelenti, melyre a folyó jövedelmek nem nyújtanak fedezetet. A tanulmány a fenti indító gondolatok mentén arra vállalkozik, hogy felmérje a megtakarítás képzés mögötti tényezőket, indítékokat, és motivációkat a pandémia utáni időszakban. A megtakarítást indukáló tényezőket a generációs hovatartozás és a pénzügyi tudatosság szempontjai mentén kívánom megvizsgálni egy Magyarországon végrehajtott kérdőíves adatfelvétel eredményei alapján.
A kulturális és kreatív ipar vizsgálata a Szigetközben : Egy kvalitatív fókuszcsoportos kutatás eredményei
Authors: Kézai Petra Kinga , Gombos Szandra
Published: November 2023

Szigetköz jelentős természeti kincsekkel rendelkező tájegysége hazánknak, amely vonzó a kulturális és kreatív ipar szereplői számára. Jelen tanulmány ezen régió 35 településén vizsgálja a kulturális és kreatív ipar helyzetét. A tanulmány nemzetközi és hazai szakirodalom elemzés által kívánja bemutatni a kulturális és kreatív iparágak (CCI) fogalom értelmezését és jelentőségét, majd pedig fókuszcsoportos felmérés (N=14) alapján értékeli az iparág vizsgált régióban betöltött szerepét. A kutatás eredményeképpen a kulturális és kreatív ipar regionális fejlesztésére fogalmaz meg javaslatokat és további kutatási irányokat.
Análisis de la realidad aumentada y el Big Data como herramientas tecnológicas aplicadas a la hostelería en un contexto Covid-19
Authors: Calderón-Fajardo Víctor
Published: November 2023

El primer capítulo se contextualiza temporal y socioculturalmente el uso de las aplicaciones móviles en la actualidad y de las nuevas tendencias del mercado en las mismas. Se analizan las preferencias de los turistas experienciales y su interés en temas relacionados sobre la salud y el bienestar del cuerpo. Finalmente, se enmarca todo lo anterior en la tecnología aplicada a la hostelería. En el segundo capítulo se plantea el crecimiento de la realidad aumentada debido a la proliferación y uso de teléfonos inteligentes en nuestra vida diaria. Se realiza una intensa investigación sobre la literatura que ha tratado el concepto de realidad aumentada. En concreto, aparece información relativa a la evolución que ha tenido la realidad aumentada desde el primer prototipo diseñado por Ivan Sutherland en 1966, hasta su explosión de prototipos en la década del 2000. Igualmente, se hace hincapié en las características que tiene una aplicación móvil con realidad aumentada, y en las ventajas y desventajas de aplicarla. Finalment en el tercer y último capítulo se realiza una definición del concepto del Big Data, su evolución histórica, su composición, sus características y sus elementos principales. Se concluye con algunos desafíos que tiene el Big Data y que aún no han quedado resueltos. Se encuentra intercalado con algunas imágenes y composiciones, de elaboración propia, que dinamizan y agilizan su comprensión. Finalmente, se realiza un análisis de las ventajas del Big Data en el sistema de gestión de procesos en el restaurante y sobre la ingeniería de menús. Además, se enfatiza la importancia que tiene como herramienta enfocada a la gestión de la oferta del menú del restaurante, en correspondencia con el comportamiento del consumidor.
TAX AMNESTY DAN PROGRAM PENGUNGKAPAN SUKARELA: MANAKAH YANG LEBIH EFEKTIF?
Authors: Faisol Moh. , Al Hakim Muhammad Taufik
Published: November 2023

Kebijakan TA dan PPS sebagai alternatif dalam rangka meningkatkan kepatuhan wajib pajak dan meningkatkan penerimaan negara. Penelitian ini bertujuan untuk mengetahui efektifitas program TA dan PPS di KPP Pratama Pamekasan. Penelitian ini menggunakan metode study kasus dengan melakukan wawancara kepada dua orang informan pegawai KPP Pratama Pamekasan. Analisis data dilakukan dengan reduksi data, penyajian data, kesimpulan dan verifikasi. Hasil penelitian ini menyatakan bahwa tinjauan efektifitas dari program TA dan PPS sebagaimana diuraikan di atas memberikan kesimpulan bahwa dari (1) aspek antusias peserta yang mengikuti TA dan PPS lebih banyak peserta yang mengikuti TA sebanyak 771 wajib pajak sedangkan PPS sebanyak 376 wajib pajak, kondisi ini karena TA merupakan program pertama dan dilakukan sosialisasi lebih intens dan menyeluruh dibandingkan dengan PPS, yang juga merupakan program lanjutan dari mereka yang belum mengikuti; dan (2) aspek penerimaan pajak lebih efektif dan lebih tinggi program TA sebesar Rp. 27.605.294.926 dibandingkan dengan PPS sebesar ± Rp. 22.249.591.880. Namun, demikian kedua program tersebut dianggap efektif karena sudah melampai target yang ditetapkan oleh KPP Pratama Pamekasan. Implikasi dari penelitian ini adalah kebijakan pajak penting dilakukan di tengah tingkat ketidakpatuhan wajib pajak tinggi, dan potensi penerimaan negara tinggi.