bluuebunny/crossref_metadata_2025 huggingface dataset:
Russian Medical Society for Arterial Hypertension expert consensus. Arterial hypertension and adherence to antihypertensive therapy
Authors: Chazova I. E. , Solntseva T. D. , Sivakova O. A. , Ageev F. T. , Fofanova T. V. , Bragina A. E. , Trushina O. Iu.
Published: June 2024

Despite the existing recommendations for the diagnosis and treatment of arterial hypertension, a wide selection of antihypertensive drugs, the efficacy of treatment of arterial hypertension remains low. The main cause for unsatisfactory control of arterial hypertension is patients’ non-adherence to treatment, which adversely affects the prognosis for cardiovascular complications. The first step in increasing adherence to antihypertensive therapy is to determine its level. There are various methods characterized by their accessibility and accuracy for assessing adherence. There are several categories of factors influencing the level of adherence. Identifying the cause in a subsequent patient is a significant step in reducing adherence to antihypertensive therapy. In addition, it’s necessary to use strategies to increase adherence to antihypertensive therapy, including both “simplification” of the treatment regimen and strengthening the doctor-patient interaction.

   The aim of this consensus is to summarize and supplement knowledge about the prevalence of adherence to antihypertensive therapy in patients with arterial hypertension, methods for assessing the level of adherence, the reasons for low adherence to the treatment of arterial hypertension and approaches to improving adherence to antihypertensive medications.
Alternative Learning System Formal Education in Jail Student Learning Experiences
Authors: S. Sala Aykinar
Published: June 2024

The purpose of this study was to explore the Alternative Learning System( ALS) Students Learning Experiences in jail in Zamboanga City in terms of describing the student’s learning experiences taking Alternative Learning System in jail, identifying the challenges experienced of the student’s taking Alternative Learning System in jail and gain an in depth understanding on how do the students in jail continue to learn in the presence of these challenges. The study employed a qualitative design utilizing a case study method and purposive sampling. This was administered to three (3) of the students under ALS program in the jail and found that their experiences were good in terms of (1) overcoming their obstacles and personal growth; (2) increasing their interest in learning due to teachers’ motivational strategies and support; (3) overcoming their hesitations due to the feeling of inappropriateness of education; (4) and experienced a long-term impact of education. However, the inmates also posted challenges despite of the positive experiences they receive from their teachers under ALS program in term of educational preparedness, struggling in comprehension and understanding, open-minded teachers and jail personnel and education for better future living. Thus, it is concluded that the ALS Program provides a realization of educational value to each of the inmates inside and a motivation as well to become a more responsible person even after breaking laws. It is also an indication that implementing ALS Program inside the Jail provided an equal opportunity for all. This study recommends further, by conducting a research on understanding the barriers faced by learners with diverse geographic and socio-economic backgrounds, more in-depth local representative studies are encouraged to inform evidence-based policymaking for the betterment of education for ALS learners.
Effect of Modified Chitosan on the Fat Oxidation of Frozen Filleted Tuna (Thunnus sp.)
Authors: Nursyam Happy , Yufidasari Hefti Salis , Budi Sasmita Bambang
Published: June 2024

This research aims to obtain the best method for the chitosan modification process by paying attention to fat content, TBA, and color (L, a*, b*). Two different chitosan production protocols, namely: DCMPA (deproteinization - decolorization - demineralization - deacetylation) as a control process and DPMCA (deproteinization - demineralization - decolorization - deacetylation)) as a modification process were used to obtain quality archived frozen tuna during storage. 30 days. The fat and color levels (a* and b*) were lowest in DCMPA using 5% acetic acid solvent. TBA content, color (L) in chitosan using 10% acetic acid solvent. Meanwhile, on the other hand, the fat content, color (a* and b*) of DPMCA chitosan used 10% acetic acid solvent, the TBA content and L value of chitosan were modified using 5% acetic acid solvent. In general, modified chitosan is able to protect tuna fillets from fat oxidation compared to standard.
Motif Akademi Halkbilimi Dergisi 2018- 2022 Yılları Arası Yayınlanmış Makalelerin Bibliyometrik Açıdan İncelenmesi
Authors: Türkan Hüseyin Kürşat , Ateş Tuba
Published: June 2024

Bilim, teknoloji ve realitenin hâkim olduğu yaşanılan çağda, sosyal bilim ve alt disiplinlerin her geçen gün geliştiği görülmektedir. Söz konusu gelişmelere paralel olarak sosyal bilimlerle ilgili çalışmalarda değerlendirmeye yönelik birtakım analiz ve yöntemlerin kullanıldığı bilinmektedir. Adı geçen onlarca yöntemlerden birisi de “bibliyometrik” analizidir. Bibliyometrik analiz, eski bir yöntem olmasına rağmen sosyal bilimler için kullanımı oldukça yenidir. Genel anlamıyla bibliyometrik analiz, yayınlanmış olan herhangi bir çalışmanın (makale, tez, süreli yayınlar, vb.) araştırma yapılan dönem içerisindeki yönelimin belirlenmesi ve tespit edilmesi amacıyla yapılır. Aynı zamanda bibliyometrik çalışma, alanla ilgili yapılan çalışmaların çeşitli özelliklerini matematiksel biçimde ortaya çıkarıp elde edilen bulgu ve tespitlerin yorumlanmasını da sağlamaktadır.
Motif Akademi Halk Bilimi Dergisi 2008 yılında dergicilik faaliyetine başlamıştır. 2008’den 2017’ye kadar yılda iki sayısı çıkarılan derginin 2018’den itibaren yılda dört sayı olarak çıkarıldığı görülmüştür. Söz konusu dergi, genel perspektifte sosyal bilimler, özelde ise daha çok halkbilimi çalışmalarının yapıldığı bir konuma sahiptir. Halk bilim ile ilgili bibliyometrik analiz yöntemi yapılacak olan bu çalışmada, Motif Akademi Halk Bilimi Dergisi’nin 2018 ve 2022 yılları arasında yayınlanan makalelerinden yararlanılacaktır. Bahsi geçen yıllarda yayınlanan makaleler, bibliyometrik analiz yöntemine tabii tutularak incelenecektir. Elde edilen verilerden hareketle oluşturulan tablolarla ilgili tespit ve tahlillerde bulunulacaktır. Araştırmada; 20 sayıda toplam 442 makale yayınlanmıştır. Verilere göre en çok makale 2020 yılında (104 makale) olduğu ve en uzun makalenin 35 sayfa olduğu, yayınlanan makalelerin birçoğunun araştırma makalesi olduğu, makalelerde kullanılan yazım dilinin daha çok Türkçe olduğu, bu makalelerde ise en çok yayım yapan araştırmacıların “Dr. Öğr. Üyesi” ünvanına sahip olduğu, tespit edilmiştir. Toplanan sonuçların adet (N) ve yüzdelik oran verileri belirlenmiştir. Verilen bu bilgiler izinde çalışmanın alana fayda sağlaması ve araştırmacılara yol göstermesi amaçlanmıştır.
Reconstruction of Binary Black Hole Harmonics in LIGO Using Deep Learning
Authors: Chatterjee Chayan , Jani Karan
Published: June 2024

Gravitational-wave signals from coalescing compact binaries in the LIGO and Virgo interferometers are primarily detected by the template-based matched filtering method. While this method is optimal for stationary and Gaussian data scenarios, its sensitivity is often affected by nonstationary noise transients in the detectors. Moreover, most of the current searches do not account for the effects of precession of black hole spins and higher-order waveform harmonics, focusing solely on the leading-order quadrupolar modes. This limitation impacts our search for interesting astrophysical sources, such as intermediate-mass black hole binaries and hierarchical mergers. Here we show, for the first time, that deep learning can be used for accurate waveform reconstruction of precessing binary black hole signals with higher-order modes. This approach can also be adapted into a rapid trigger generation algorithm to enhance online searches. Our model, tested on simulated injections in real LIGO noise from the third observing run (2019–2020) achieved a high degree of overlap with injected signals. This accuracy was consistent across a wide range of black hole masses and spin configurations chosen for this study. When applied to real gravitational-wave events, our model's reconstructions achieved between 85% and 98% overlap with those obtained by Coherent WaveBurst (unmodeled) and LALInference (modeled) analyses. These results suggest that deep learning is a potent tool for analyzing signals from a diverse catalog of compact binaries.
Primerjava Josipa Jurčiča in Ivana Cankarja z računalniškimi metodami za zaznavanje semantičnih premikov
Authors: Žejn Andrejka , Pranjić Marko , Pollak Senja
Published: June 2024

V prispevku uvodoma predstavimo heterogenost in interdisciplinarnost digitalne humanistike kot dva osrednja in medsebojno povezana koncepta. V osrednjem delu vpeljemo uporabo metode zaznavanja semantičnih premikov z uporabo kontekstualnih besednih vložitev pri analizi literarnih del. Potencial metode prikažemo na primerjalni analizi pripovednih opusov Josipa Jurčiča in Ivana Cankarja, kanoničnih slovenskih avtorjev, ki sta ustvarjala v različnih obdobjih, in sicer z avtomatskim prepoznavanjem besed, katerih pomeni se med avtorjema najbolj razlikujejo. Nadaljnja interpretacija temelji na kvalitativni analizi avtomatsko pridobljenih rezultatov in na uvrščanju besed, prepoznanih kot relevantnih za razlike med Jurčičevim in Cankarjevim slogom, v pomenska polja. Pokazali smo, da je pristop, ki temelji na kontekstualnih besednih vložitvah, mogoče uporabiti za analize literature z zadovoljivimi rezultati. S tem z vidika literarne zgodovine ponujamo nov vpogled v Cankarjevo in Jurčičevo pripovedništvo, saj pokažemo, da razlika med Jurčičevim (romantičnim) realizmom in Cankarjevo moderno sloni tudi na semantiki besed, povezani z gibanjem ter družbenimi in psihološkimi dejanji in procesi.
Augmented Reality in Elementary Education: System Architecture for Implementing an Interactive and Immersive E-Learning Application
Authors: Ghosh Apurba , Ghosh Anindya , Uddin Md. Salah , Rahman Mizanur , Hasan Kazi Jahid
Published: June 2024

Early childhood language acquisition is crucial, but complex scripts such as Bengali present challenges. BIPLOB, an Android-based augmented reality (AR) application, seeks to revolutionize language learning by introducing interactive 3D models and meticulously recorded audio pronunciations. Targeting both engagement and accuracy, BIPLOB addresses issues encountered by traditional methods. Its optimized workflow offers a replicable framework for future AR-based language learning applications, especially for complex scripts. BIPLOB paves the way for immersive and effective early language acquisition through the transformative power of AR technology.
On-Device Neural Network for Object Train and Recognition using Mobile
Authors: Uddin Md. Salah , Slany Wolfgang , Hasan Kazi Jahid
Published: June 2024

A neural network is a machine learning (ML) program or model that processes information and recognizes patterns, similar to the human brain. The neural network algorithm operates by training on data to learn and enhance its accuracy. If there is any mistake in the learning process, the machine will react unexpectedly and produce incorrect information. So, whenever a neural network model is developed, it is mandatory to evaluate its performance and ensure its output is accurate. Cameras, touchscreens, internet connectivity, and powerful CPUs have contributed to the popularity of smartphones. Mobile apps are software applications that run on smartphones. ML enhances mobile app functionality by offering features such as voice recognition, image analysis, natural language processing, personalization, and recommendations. Training ML models using mobile apps is challenging due to limited resources, data, and privacy concerns. Object recognition is a neural network-based technique that enables the identification and localization of objects in an image or video. This technique is used in driverless cars, disease identification, industrial inspection, robotics, and more. In this paper, the author introduces a new neural network-based algorithm that utilizes mobile devices for training and recognizing images. Although mobile devices have some technological limitations for training, well-established guidelines for systematically mapping verification and validation techniques have been used in the proposed neural network to ensure performance and correctness in on-device object training and recognition.
Modelling User Behavior Towards Smartphones and Wearable Technologies
Authors: Jamalova Maral
Published: June 2024

The study employs bibliometric and content analysis to assess the current status of applying technology adoption models (such as the Technology Acceptance Model (TAM), Unified Theory of Acceptance and Use of Technology (UTAUT), and Innovation Diffusion Theory (IDT)) to the smartphone market, which also encompasses smart wearables. Hereby, the author aims to explore the relationship between smartphone usage and adoption models and contribute to the literature through current trends and methodologies. To achieve the goal, the author applied a two-stage approach. In the first stage, 213 articles were analyzed using citation and bibliographic coupling tools in VOS viewer (version 1.6.20). The papers were selected from the Scopus database, and the search was conducted in the fields of economics, business, and computer technologies. In the second stage, the author conducted a brief literature review of the most influential papers. The results illustrate the situation regarding the implementation of various models in the case of smartphone adoption. Content analyses of the most influential papers were conducted to elucidate and enhance the findings of bibliometric analyses, identify research gaps, and guide future research development.
Des œuvres en morceaux et des trous sur les murs. La difficulté d’écrire la vie des œuvres du Pérugin au XIXe siècle
Authors: Dumas Éloïse
Published: June 2024

Parmi les milliers d’œuvres ramenées à Paris par les troupes napoléoniennes, on en compte vingt-six attribuées au Pérugin et presque toutes proviennent de Pérouse. La géographie des œuvres en est bouleversée. Une fois en France, les tableaux sont dispersés dans les musées de province et les commissaires des États italiens renoncent à les récupérer en 1816, se concentrant sur celles restées au Louvre. Celles provenant de Pérouse n’y reviendront jamais, elles sont gardées pour la nouvelle Pinacothèque vaticane. L’entrée au musée représente un tournant dans la vie des œuvres. C’est à partir de là que commence un travail d’appropriation matérielle, intellectuelle et affective. À Pérouse, leur absence laisse place au souvenir qui fige l’érudition et participe de la cristallisation de la conscience communale. Ce bouleversement dans la vie des objets marque profondément leur biographie, que les historiens rédigent tout au long du siècle, réunissant dans les livres les retables démembrés.
La vie des Gommes : pour une approche biographique des pneus de Carol Rama
Authors: Spovieri Carolina
Published: June 2024

Les événements biographiques semblent souvent motiver les œuvres de Carol Rama (1918-2015). Les bandes en caoutchouc utilisées pour la série des Gommes (1970) sont par exemple présentées comme les chambres à air d’anciens pneus de bicyclette, provenant de l’usine paternelle. Si ces bandes en caoutchouc ont pu susciter un certain intérêt, c’était généralement pour les étudier du point de vue de la vie passée de Rama, en les ramenant à la tragédie familiale du suicide de son père. Mais en dépassant une telle approche biographique, quittant alors la vie de l’artiste pour suivre la trajectoire historique des bandes en caoutchouc (usage et fonction ordinaires du pneu, emploi comme matériau artistique), il devient possible de soulever de nouvelles hypothèses pour lire l’œuvre autrement. D’abord, si l’origine marchande de l’objet nous ouvre à son caractère périssable, l’état usé du pneu nous renseigne aussi sur le choix de l’artiste à l’intégrer dans son œuvre, elle qui aime « les choses qui font vécu » (Vergine, 1985). En l’arrachant à son statut de marchandise inutilisable, le geste créatif confère au déchet une sorte de nouvelle mémoire, comme une seconde vie qui le rendrait du même coup autonome. De même, le processus de vieillissement du pneu, mis au premier plan dans la série, pourrait ironiquement pointer la courte vie des objets de la société bourgeoise dont Rama était issue, et simultanément indiquer l’obsolescence du support lui-même car l’objet remplace la peinture. De plus, les Gommes sauraient contenir « la crise du tableau comme institution normale à la peinture de notre passé » (Sanguineti, 1994). Prendre au sérieux les facteurs multiples qui contribuent à tracer la vie de ces bandes en caoutchouc permettrait de réfléchir aux dimensions interprétatives de l’art à partir de la biographie des matériaux et non seulement de celle de l’artiste.
De fil palatial en aiguille patrimoniale. La soierie du cabinet de repos du petit appartement de Napoléon Ier à Versailles.
Authors: Gressé-Denois Laureen
Published: June 2024

Au printemps 2024, le château de Versailles présentera les soieries lyonnaises de Napoléon Ier pour les palais de Versailles et de Trianon. D’or en abeilles, de fleurs en nuances, ces textiles n’auront jamais été installés, la chute de l’Empire entraînant leur remise au Garde-Meuble. Pourtant, leur destinée témoigne de l’entrecroisement, au fil du temps, de nombreux remplois, acteurs et discours. Passant de régime monarchique à républicain, de souverains et soyeux d’antan aux conservateurs et restaurateurs d’aujourd’hui, ils révèlent une histoire sensible, sociale, économique, politique et patrimoniale à laquelle ils prennent activement part. Pour illustrer ce riche devenir, cet article se propose de revenir sur cinq aspects d’agentivité à travers la biographie du gros de Tours blanc broché soie nuée du cabinet de repos des petits appartements de l’Empereur. De sa création au sein d’un plan de relance napoléonien et de ses remplois par souci d’économie après 1815 à ses ornements véhiculant un discours symbolique, le parcours de ces soieries est en effet dessiné dans un premier temps par des intentions économiques et politiques. Témoin de la volonté impériale, il est ensuite doté d’une aura mémorielle au château de Malmaison, dédié au souvenir napoléonien au début du XXe siècle, avant de servir également d’agent immersif dans la muséographie des attiques Chimay et du Midi au château de Versailles, repensés par Gérald Van der Kemp. Enfin, son agentivité patrimoniale s’illustre par ses retissages, notamment à l’hôtel de Beauharnais, préservant un savoir-faire historique. L’article analyse pour finir le parti pris scientifique et scénographique de l’exposition versaillaise de 2024.
De l’Anjou à la Bohême : le double portrait équestre de Pierre de Rohan-Gié
Authors: Alis Jeanne
Published: June 2024

Au XIXe siècle, le château de Sychrov en Bohême du Nord devient le fief d’une branche de la famille de Rohan. Les vitres de la demeure conservent de cette période un double portrait équestre de Pierre de Rohan (1451-1513) réalisé à la demande de l’un de ses descendants le Prince Camille de Rohan (1800-1892). Précieux témoins de l’histoire de la famille, la présence de ces modèles artistiques interpelle : en effet, ceux-ci sont issus d’œuvres qui, agrémentant le château du Verger à la toute fin du Moyen Âge, disparaissent au XVIIIe siècle soit un siècle avant leur réemploi à Sychrov. Dans cet article, il s’agira de revenir sur la conception de ce vitrail et de remonter aux origines du modèle artistique employé pour faire l’histoire d’un objet disparu à travers ses copies successives.
Integração de pessoas com deficiência visual no mercado de trabalho em Portugal: Contributos para a identificação de boas práticas
Authors: Andrade Ana , Henriques Lúcia , Silva Isabel S. , Costa Daniela
Published: June 2024

Dados estatísticos recentes e estudos realizados em Portugal revelam a dificuldade que pessoas com deficiência visual enfrentam na integração no mercado de trabalho. O presente trabalho surgiu com o objetivo de identificar e dar a conhecer boas práticas que as entidades empregadoras podem (e devem) adotar, esperando-se desse modo contribuir para a promoção da integração das pessoas com deficiência visual no mercado de trabalho. Para o efeito, recorreu-se à revisão da literatura, tendo-se privilegiado nessa revisão as recomendações nacionais e europeias neste domínio e os estudos realizados em Portugal cujo objetivo se centrava precisamente na compreensão do processo de integração profissional de pessoas com deficiência visual.
Carbonate Hydroxyapatite - A Multifunctional Bioceramics with Non-Medical Applications
Authors: Adekanmi Daniel Gbenga , Garcia Carlos Rodriguez , Lopez-Badillo Claudia M.
Published: June 2024

Carbonate hydroxyapatite is the common derivative of hydroxyapatite found in living systems. It is the building block of most hard tissues, including the teeth and bones. A vast majority of the applications of this versatile material focus on its biomedical applications, which is attributable to its closeness to biological apatites. Hydroxyapatite is a strong precursor to carbonate apatite in nature, and many experiments show that both are similar in a few respects. A significant divergence point is carbonate's obvious impact on its physicochemical properties and concomitant applications. The inclusion of carbonate ions into the lattice of hydroxyapatite results in morphological and physicochemical changes that vary with the method of synthesis and extent of substitution. The unique crystal structure, improved surface area, and porous morphology of carbonate hydroxyapatites also make it useful for catalysis and environmental remediation as adsorbents for heavy metals. This review briefly examines carbonate hydroxyapatite, its synthesis, its modification, and its characterization. It also highlights its biomedical applications while drawing attention to its non-medical potential.
Electroless Synthesis of Ni-P-ZrO2 Nanocomposite to Analyse Corrosion
Authors: Hassan Suriaya , Sharma Sulaxna , Sharma Awanish , Tripathi Ankita
Published: June 2024

Electroless Synthesis of Nicle phosphate zirconium dioxide (EL NiP/-ZrO2) has been carried out with ZrO2 nanocomposite (50 to 160 nm and concentration 4 gpl) and randomly dispersed into an alkaline Ni-P electroless bath (pH 8.0). The deposited thickness of NiP/-ZrO2 nanocoatings resting on mild steels (MS) substrate (AISI 1040 grade) is carried out to evaluate the surface morphology and elemental composition. The SEM, EDAX and XRD methods elucidated clear difference between Ni-P along with NiP/-ZrO2 nanocomposite coatings. Moreover NiP/-ZrO2 nanocoatings contain uniform burly of ZrO2 nanoparticles like whitish globules. Further the as-coated Ni-P/-ZrO2 nanocoatings revealed mostly amorphous structures, while in heated coatings (temperatures 150, 350, and 550 °C with pure Ar) as temperature rises, the amorphous structure transformed leisurely to crystalline structure. The microhardness values in Vickers-unit of the developed nanocomposite coatings are determined and it is found that for a particular load with increase of temperature microhardness as well as corrosion resistancealso increases. Keywords: Electroless; Corrosion; Ni-P/-ZrO2; nanocoatings; Microhardness
The Effect of Modified Material in Screen-Printed Carbon Electrode for Oxalic Acid Detection
Authors: Bayu Indra , Madurani Kartika A. , Kurniawan Fredy
Published: June 2024

In this study, we investigated the effect of modified material on screen-printed carbon electrode (SPCE) for detection of oxalic acid. The SPCE was modified with (1) carbon conductive ink and (2) combination of carbon conductive ink and nickel nanoparticles (Ni-NPs). Modification process of (1) was conducted using drop-cast method by adding a mix of carbon conductive ink and nickel nanoparticles (1:1) on the surface of SPCE. Modified SPCE was then dried and stored in desiccator. Performance test of SPCE with and without modification was carried out using cyclic voltammetry (CV) method. The CV scan was done at the range of-0.5 to 1.5 V with scan rate of 100 mV/s in 20 mM oxalic acid solution. The result showed that carbon conductive ink and nickel nanoparticles mix (1:1) modified SPCE could be used to detect oxalic acid on potential 1.2 V.
Effects of Leaching Agents on Pb and Cd Immobilization in Battery Waste Contaminated Soils Amended with Bare and Stabilized Zero-Valent Iron Nanoparticles
Authors: Adedokun Rosemary , Ogungbesan Shephrah Olubusola , Anegbe Bala , Okuo James , Ayesa Samuel Abayomi , Ikpe Edidiong Emmanuel
Published: June 2024

This study compared the effectiveness of bare zero-valent iron nanoparticles (B-nZVI) and starch-stabilized zero-valent iron nanoparticles (S-nZVI) in immobilizing Pb and Cd from lead-acid battery waste soils. Both B-nZVI and S-nZVI were prepared in almost identical manner using the technique of reducing ferric chloride with sodium borohydride. X-ray diffraction (XRD) and dynamic light scattering (DLS) analyses confirmed that polydisperse B-nZVI and S-nZVI were synthesized. XRD and DLS analyses showed that B-nZVI and S-nZVI had different surface properties. To assess the immobilization capability of B-nZVI and S-nZVI, a composite soil sample was collected from an automobile lead-acid battery waste dumpsite. The soil sample had a pH of 3.85 and Pb and Cd levels of 16,674 mg/kg and 41 mg/kg, respectively. Single extraction procedures using 0.01M CaCl2, 0.1 M HCl, and 0.05 M EDTA were used to simulate phytoavailable Pb and Cd in the soil studied. Batch immobilization analysis showed that Cd was mobile in the control but immobile in B-nZVI and S-nZVI treated soils. Pb was however not immobile in either the control or treated soils. The mobility of Pb however decreased with increasing doses of S-nZVI and 0.003 g of S-nZVI was needed to make Pb completely immobile in soil. Batch immobilization also showed that S-nZVI was 1.8-2.49 times more efficient in immobilizing Pb than B-nZVI. Simulated phytoavailability of Pb was in the order of EDTA > HCl > CaCl2 > H2O while simulated photoavailable Cd was in the order of HCl > EDTA > H2O > CaCl2.
Highly Porous Ni Electrode Decorated with Fe3O4 for Oxygen Evolution Reaction(OER)
Authors: Wardhana Bayu Satria , Lee Sheng Wei , Jang Jason Shian Ching
Published: June 2024

Hydrogen is an environmentally friendly energy source that can be extracted from water through electrolysis. However, the slow oxygen evolution reaction (OER) at the anode side is the main obstacle to the widespread use of water-splitting devices. This study used self-developed highly porous nickel structures (SMNF) and commercial nickel foam (CNF) as working electrodes in the electrolysis process. Iron (II, III) Oxide (Fe3O4) as a catalyst is coated with a dip coating technique on the Ni porous structure and then calcined using a laser process to produce a Ni-Fe3O4-based electrode. Electrochemical test results show that the presence of Fe3O4 significantly impacts high reaction kinetics. The SMNF-Fe3O4 demonstrated an overpotential of 217,3 mV at 1 M KOH electrolyte, at a current density of 10 mA, lower to SMNF electrode without Fe3O4 with an overpotential of 361,4 mV under the same conditions. In addition, the difference in porosity less significantly affects the electrode's effectiveness due to the slight difference in mass loading, which is only < 5 mg. However, electro-impedance spectroscopy (EIS) testing shows better performance on SMNF-Fe3O4 with a smaller electrical series resistance (ESR), around 0.638 Ω, compared to CNF-Fe3O4, which is 0.767 Ω. Overall, observations by chronoamperometry test at an overpotential of 155 mV at 5 hrs show stable performance of SMNF-Fe3O4 electrodes.
Simulation of Stress Intensity Factor and J-Integral on UIC 54 Railway Failure Using A Fracture Mechanics Approach
Authors: Kurniawan Pradhana , Darto Darto , Iswantoko Agus , Sutrisno Feliks
Published: June 2024

Repeated loading on the railroad tracks will result in fatigue failure. Fatigue failure combined with a defect in the form of a crack in the railroad track will result in a decrease in strength. Defects in the form of cracks are formed due to improper manufacturing and treatment processes. One treatment that can cause the formation of defects in the form of cracks is thermite welding. Improper and non-standard thermite welding techniques can trigger the formation of defects in the form of cracks in the railroad joints. Based on these problems, this simulation aims to obtain information about the value of maximum stress, SIF, J-Intergal, number of cycles, and crack extension from variations in crack size to repeated loading. The method consists of preprocessing, processing and postprocessing. Preprocessing begins with the design of the UIC 54 railroad crack which consists of 3 variations of crack length, namely 10 mm, 15 mm, and 20 mm. The design was tested through static structural simulation using the ANSYS 2021 R2 application. Meshing is configured using an element size of 5 mm and uses curvature capture. The results of the simulation obtained maximum stress values, SIF, J-Integral, number of cycles, and crack extension. Based on the simulation of SIF 1 and J-Integral values on the specimen design with a crack length of 10 mm it shows 362.03 Mpa.mm1/2 of 0.5708 mJ/mm2, for an initial crack length of 15 mm that is equal to 482.81 Mpa.mm1/2 and 0.91738 mJ/mm2, and for an initial crack length of 20 mm, it is 600.54 Mpa.mm1/2 and 1.4465 mJ/mm2. The results show that the increase in SIF 1 and J-Integral will be proportional to the increase in the initial crack length value. .
Inflammatory Profiles Induced by Intranasal Immunization with Ricin Toxin-immune Complexes
Authors: Tolman Lindsey E , Mantis Nicholas J
Published: June 2024

The underlying contribution of immune complexes in modulating adaptive immunity in mucosal tissues remains poorly understood. In this report, we examined, in mice, the proinflammatory response elicited by intranasal delivery of the biothreat agent ricin toxin (RT) in association with two toxin-neutralizing mAbs, SylH3 and PB10. We previously demonstrated that ricin-immune complexes (RICs) induce the rapid onset of high-titer toxin-neutralizing Abs that persist for months. We now demonstrate that such responses are dependent on CD4+ T cell help, because treatment of mice with an anti-CD4 mAb abrogated the onset of RT-specific Abs following intranasal RICs exposure. To define the inflammatory environment associated with RIC exposure, we collected bronchoalveolar lavage fluid (BALF) and sera from mice 6, 12, and 18 h after they had received RT or RICs by the intranasal route. A 32-plex cytometric bead array revealed an inflammatory profile elicited by RT that was dominated by IL-6 (>1500-fold increase in BALF) and secondarily by KC (CXCL1), G-CSF, GM-CSF, and MCP-1. RICs induced inflammatory profiles in both BALF and serum response that were similar to RT, albeit at markedly reduced levels. These results demonstrate that RICs retain the capacity to induce local and systemic inflammatory cytokines/chemokines that, in turn, may influence Ag sampling and presentation in the lung mucosa and draining lymph nodes. A better understanding of the fate of immune complexes following intranasal delivery has implications for the development of mucosal vaccines for biothreats and emerging infectious diseases.
Longitudinal effects of land-cover transitions on the periphyton community of a tropical stream
Authors: Da Silva Bruna Suelen , Zandona Eugenia , Neres de Lima Vinicius , Moulton Timothy P. , Tromboni Flavia , Thomas Steven A. , Feijó-Lima Rafael
Published: June 2024

Our study aims to investigate the longitudinal effects of two land-cover transitions on the periphytic algal community. We utilized datasets from three different studies conducted over a 5-year interval in a tropical headwater stream. The studied stream traverses two abrupt adjacent transitions from an upstream forest to a pasture and back to a downstream forest remnant. We performed a high-spatial resolution sampling and used generalized additive models (GAMs) to capture the non-linear gradient response of algal metrics to distance from land-cover transitions. Algal biomass presented a lagged response to increased light availability along the pasture section and decreased along a shorter distance in the downstream forest. Most algal metrics presented a lagged response to transitions, with chlorophyll-a taking up to 375 m to reach the maximum values inside the pasture and up to 300 m to return to reference conditions inside the downstream forest. In the downstream forested section, diatom richness and abundance were similar to the upstream forested section but did not return to reference conditions. The results were consistent across years. Our results indicate that, while riparian forest remnants can play an important role in buffering impacts related to land-cover changes in low order streams, both the magnitude and directionality of these effects might be influenced by longitudinal effects caused by the flow of water. Riparian forest remnants can have a longitudinal effect in stream conditions, influencing environmental characteristics even over non-forested reaches, to where the forest conditions can be propagated downstream by the flow of water.
Die magaliesberg
Authors: Ferreira O.J.O.
Published: June 2024

No abstract available.
The impact of high-altitude and cold environment on brain and heart damage in rats with hemorrhagic shock
Authors: Xu Jun , Yu Wantong , Li Ning , Li Sijie , Wang Xiaojie , Gao Chen , Liu Feng-Yong , Ji Xunming , Ren Changhong
Published: June 2024

BACKGROUND:

Hemorrhagic shock (HS) causes severe organ damage, worsened by high-altitude conditions with lower oxygen and temperatures. Existing research lacks specific insights on brain and heart damage under these conditions. This study hypothesizes that high-altitude and cold (HAC) environments exacerbate HS-induced damage in the brain and heart, aiming to improve treatment strategies.

MATERIALS AND METHODS:

Twenty-four male Sprague-Dawley (SD) rats (200–250 g of weight) were randomly assigned into sham, HS + normal, HS + HAC (4,000 m), and HS + HAC (6,000 m). The HS model was established in SD rats (35% loss of total blood volume), and histopathological injuries of the brain and heart were detected using hematoxylin and eosin staining, Sirius red staining, and immunohistochemistry. Apoptosis of the brain and heart tissues was detected by terminal transferase-mediated dUTP nick end labeling (TUNEL) immunofluorescence staining. To determine the levels of tumor necrosis factor-α (TNF-α), interferon-gamma (IFN-γ), monocyte chemoattractant protein-1 (Mcp-1), BCL2-associated X (BAX), and myeloid cell leukemia-1 (Mcl-1) protein, western blotting assay was used.

RESULTS:

The HAC environment induced pathological damage to the brain and heart and aggravated the degree of cardiac fibrosis in HS rats. However, it did not cause apoptosis of the brain and heart. In addition, it upregulated TNF-α, IFN-γ, Mcp-1, and BAX protein levels, but downregulated Mcl-1 protein levels (P < 0.05).

CONCLUSIONS:

The HAC environment aggravated the degree of brain and heart damage in HS rats, which may be related to neuron nucleus pyknosis, myocardial fibrosis, and inflammatory and apoptosis activation.
Primary antiphospholipid syndrome in the elderly: Four strokes and mechanical thrombectomies until the diagnosis - A case report
Authors: Anastasiadi Anatoli , Bott Chiara , Kitterer Daniel , Roser Elke , Henkes Hans , Bäzner Hansjörg , Wolf Marc E.
Published: June 2024

Antiphospholipid syndrome (APS) is known as a rare etiology of embolic ischemic stroke. In individuals below 50 years, up to 20% of strokes are associated with APS, whereas in patients >50 years, it is considered a very seldom cause of stroke. We describe the course of a 66-year-old white woman, who experienced four embolic strokes with large vessel occlusion over a period of 2 years, which were repeatedly and successfully treated by mechanical thrombectomy. Initially attributed to atrial fibrillation and treated with direct oral anticoagulants, the patient was finally diagnosed with primary APS due to isolated anti-beta 2-glycoprotein antibodies and successfully treated after several stroke recurrences. After initiation of Vitamin K antagonist therapy, no further strokes occurred. For recurrent embolic stroke despite oral anticoagulation, late-onset APS might be considered a rare etiology also in the elderly.
A bibliometric review of unilateral neglect: Trends, frontiers, and frameworks
Authors: Zhao Wanying , Ye Linlin , Cao Lei , Song Weiqun
Published: June 2024

BACKGROUND:

Owing to the adverse effects of unilateral neglect (UN) on rehabilitation outcomes, fall risk, and activities of daily living, this field has gradually got considerable interest. Notwithstanding, there is presently an absence of efficient portrayals of the entire research field; hence, the motivation behind this study was to dissect and evaluate the literature published in the field of UN following stroke and other nonprogressive brain injuries to identify hotspots and trends for future research.

MATERIALS AND METHODS:

Original articles and reviews related to UN from 1970 to 2022 were retrieved from the Science Citation Index Expanded of the Web of Science Core Collection. CiteSpace, VOSviewer, and Bibliometrix software were used to observe publication fields, countries, and authors.

RESULTS:

A total of 1,202 publications were incorporated, consisting of 92% of original articles, with an overall fluctuating upward trend in the number of publications. Italy, the United Kingdom, and the United States made critical contributions, with Neuropsychologia being the most persuasive academic journal, and Bartolomeo P. ranked first in both the quantity of publications and co-citations. Keywords were divided into four clusters, and burst keyword detection demonstrated that networks and virtual reality might additionally emerge as frontiers of future development and warrant additional attention.

CONCLUSIONS:

UN is an emerging field, and this study presents the first bibliometric analysis to provide a comprehensive overview of research in the field. The insights and guidance garnered from our research on frontiers, trends, and popular topics could prove highly valuable in facilitating the rapid development of this field while informing future research directions.
The effects of stress hyperglycemia in diabetic and nondiabetic patients with large vessel occlusions undergoing mechanical thrombectomy
Authors: Kasturiarachi Brittany M. , Saeed Omar , Gachechiladze Leila , Alsbrook Diana , Singh Savdeep , Zaid Ghaida , Eswaradass Prasanna , Goyal Nitin , Elangovan Cheran , Arthur Adam S. , Alexandrov Andrei V , Krishnaiah Balaji
Published: June 2024

INTRODUCTION:

Diabetes and hyperglycemia are major risk factors that can increase infarction volume and contribute to poor functional status. Our study aim was to investigate the effect of stress hyperglycemia on various safety and efficacy outcomes in patients with large vessel occlusions (LVOs) undergoing mechanical thrombectomy (MT) with or without diabetes.

METHODS:

A retrospective analysis of consecutive LVO patient data treated with MT at a Comprehensive Stroke Center in the Mid-South was conducted. Adult patients with LVO on computed tomography angiography (CTA) and treated with MT within 24 h of symptom onset were included. The primary outcome was to determine if there was an association in collateral flow or infarct size in the setting of hyperglycemia. Secondary outcomes included National Institute of Health Sciences Score (NIHSS) and Modified Rankin Score (mRS).

RESULTS:

A total of 450 patients underwent MT, out of which 433 had baseline hemoglobin A1c recorded: mean age: 64 ± 15 years, 47% women, pretreatment NIHSS median 15 points (interquartile range 10–19), 323 (75%) with good collaterals grades >2 on multiphasic CTA, 326 (75%) were non-diabetic, and 107 (25%) were diabetic. Nondiabetics with stress hyperglycemia had a tendency toward higher pre-treatment NIHSS scores (mean 17.5 ± 7.6, P = 0.02) and at 24-h (12.9 ± 9.0, P = 0.02), poor collaterals (multiphasic CTA score ≥2; 21.4% vs. 34.5%, P = 0.02), larger infarct volumes (50.7 ± 63.6 vs. 24.4 ± 33.8 cc, P < 0.0001), and had poorer functional outcomes (good mRS 0–2 47.7% vs. good mRS 0–2 36.8%) when compared to nondiabetics without stress hyperglycemia. For every 1 mg/dL increase in admission blood glucose, there was a 0.3 cc increase in infarct volume (95% confidence intervals for β =0.2–0.4; P < 0.0001) after adjusting for the final thrombolysis in cerebral infarction score.

CONCLUSIONS:

LVO patients with stress hyperglycemia without previously diagnosed diabetes had more severe strokes, developed larger infarct volumes, poorer collaterals, and had worse functional outcomes at 90 days post-MT. In addition, LVO patients with diabetes and stress hyperglycemia exhibited more passes during MT and worse functional outcomes.
Palliative Right Ventricular Outflow Tract Stenting in Tetralogy of Fallot with Severe Cyanosis: Experience from a Single Center in Southern India
Authors: Priyadarshini Bhavana , Kasturi Sowmya , Reddy Srinath N. , Mohanty Satish
Published: June 2024

Background:

This study conducted at an Indian tertiary care hospital aimed to characterize the clinical profile of tetralogy of Fallot (ToF) patients undergoing right ventricular outflow tract (RVOT) stenting and assess their immediate postprocedural outcomes until discharge.

Methods:

In this retrospective analysis, the clinical and procedural outcomes were analyzed for 20 patients who underwent palliative stenting in the RVOT for severe cyanosis associated with ToF during 2021–2023.

Results:

The median age for the patients was 2.3 years (range 3 months–21 years), two being adults (>18 years). Fourteen (70%) patients underwent elective RVOT stent and 30% underwent emergency stenting. The most common indication of RVOT stenting was hypoplastic branch pulmonary arteries (PAs) (n = 11, 78.6%) and cyanotic spell (n = 4, 66.7%) for elective and emergency surgeries, respectively. The average improvement in SpO2 was 27.2% (95% confidence interval 23.4–31.0, P < 0.001). Six (30%) patients had complications including reperfusion injury of lungs (n = 2, 33.4%) sepsis (n = 1, 16.7%), stent embolization (n = 1, 16.7%), re-stenting (n = 1, 16.7%), transient complete heart block (n = 1, 16.7%) during the procedure, and. One child went through RVOT stent postoperative due to severe residual stenosis and child developed severe tricuspid regurgitation and succumbed to death due to culture positive sepsis with multi-organ dysfunction. Rest (n = 19, 95%) were discharged with an average 6.7 days of hospital stay.

Conclusion:

ROVT stenting is a safe and effective palliative management in ToF enhancing oxygen saturation prior to definitive surgical repair.
Troponin-I as a Prognostic Marker in Patients with Coronavirus Disease 2019: Insights from a Single-center Investigation
Authors: John Dany , Kawade Ramesh , Shelke Abhijeet B
Published: June 2024

Background:

Troponin-I is conventionally correlated with myocardial injury, but its relevance in assessing the severity of coronavirus disease 2019 (COVID-19) and its implications for patient management remains an area of ongoing investigation. This study was designed to assess the correlation between troponin-I levels and the disease severity among patients with COVID-19.

Materials and Methods:

This retrospective study was conducted at a tertiary care center in India between April 2020 and November 2021. The patients with reverse transcription-polymerase chain reaction who tested positive for COVID-19 infection, and who underwent troponin-I examination at presentation were included in the study. A comparison of baseline clinical characteristics among patients who survived and who did not survive post-COVID-19 was done, and risk factors associated with mortality among hospitalized patients were analyzed.

Results:

A total of 1673 patients were enrolled in this study. Of these, 1431 patients survived, and 242 patients did not survive post-COVID-19. The mean age of the patients with troponin-I levels ≤0.06 ng/ml was 49.66 ± 17.88 years and that of patients with troponin-I levels >0.06 ng/ml was 60.13 ± 20.04 years. The nonsurvival rate was high in patients aged >50 years compared to the patients aged ≤50 years (81.4% vs. 18.6%; P < 0.001). The mortality rate was high in patients with troponin-I levels >0.06 ng/ml compared to the patients with troponin-I levels ≤0.06 ng/ml (51.7% vs. 48.3%; P < 0.001). Breathlessness (odds ratio [OR]: 26.901; P < 0.001), cut-off troponin-I levels (OR: 8.246; P < 0.001), and other comorbidities (OR: 8.246; P < 0.001) were independently correlated with mortality among hospitalized patients with COVID-19.

Conclusion:

This study demonstrated that elevated troponin-I level at presentation was associated with disease severity and increased mortality in patients with COVID-19.
A Cross-sectional Analytical Study of Morphological Patterns of Acanthosis Nigricans and Its Association with Components of Metabolic Syndrome
Authors: Parmar Brijesh Vinubhai , Pala Nilam
Published: June 2024

Background:

Acanthosis nigricans (AN) is a dermatosis that manifests as asymptomatic and symmetrical darkening, affecting the skin of intertriginous areas. It is a marker of insulin resistance and is usually associated with metabolic syndrome (MS). The present study was conducted to study the morphological patterns of AN and to assess its correlation with different components of MS.

Methodology:

Using the purposive sampling technique (1-year period), 100 patients fulfilling the case definition of AN were enrolled based on the inclusion and exclusion criteria. A detailed history and a cutaneous examination (color, texture, and sites of AN) were done. Anthropometric measurements and scoring of the AN were done. Investigations were reviewed. Data were recorded, and MS was diagnosed using the National Cholesterol Education Program’s Adult Panel III criteria. The data were analyzed using Microsoft Excel 13 software.

Results:

The mean age was 36.9 ± 10.1 years, with a male-to-female ratio of 1:1.38. The mean duration of AN was 18.8 ± 12.5 months. Seventy percent of cases had involvement of two or more sites. MS was present in 55% of cases of AN. Gender, duration of AN, site of AN, neck and axilla severity, and total cholesterol were not statistically significantly associated with MS (P > 0.05). Its association with systolic and diastolic blood pressure, waist circumference, fasting blood sugar, and high triglyceride was found to be statistically significant (P < 0.05). A low high-density lipoprotein level was found to be highly significant (P < 0.01). On applying the Chi-square test, all five parameters of MS had a significant association with AN.

Conclusion:

Understanding the relationship between AN and MS is important, as patients with AN are at risk for all the components of MS individually and collectively.
A Case of Dilated Cardiomyopathy and Concomitant Cardiac Syndromes: The Lost Cause Regained with Cardiac Resynchronization Therapy with Defibrillator Implantation
Authors: Sharma Sanjay Kumar
Published: June 2024

A 50-year-old male patient with cardiomyopathy (New York Heart Association Class IV, left ventricle ejection fraction of 15%, left bundle branch block, intermittent supraventricular tachycardia, tricuspid regurgitation, and mitral regurgitation) was qualified for a cardiac resynchronization therapy with defibrillator (CRT-D) procedure. CRT-D has become an integral part of systolic heart failure therapy. It can minimize rehospitalization, improve the exercise capacity and well-being of the patient, and potentially decrease mortality. After the CRT-D implantation, electrocardiographic changes were found to be reverted. No hospitalization was reported at 2-year follow-up. The patient survived and regained his quality of life.