bluuebunny/crossref_metadata_2025 huggingface dataset:
Terahertz electromagnetically-induced transparency of self-complementary meta-molecules on Croatian checkerboard
Authors: Zhao Zhenyu , Zheng Xiaobo , Peng Wei , Zhang Jianbing , Zhao Hongwei , Shi Wangzhou
Published: April 2019

A terahertz (THz) electromagnetically-induced transparency (EIT) phenomenon is observed from two types of self-complementary meta-molecules (MMs) based on rectangular shaped electric split-ring resonators (eSRR) on Croatian checkerboard. Each MM contains a couple of identical size eSRRs and a couple of structural inversed eSRRs twisted π/2 in checkerboard pattern. In the first type of MM (type-I), the gap is in the middle line of eSRR. In the second type of MM (type-II), the gap is on the two arms of eSRR. Both types of MMs exhibit EIT effect. A maximum 20 ps group delay is observed at the transparency window of 0.63 THz in type-I MM; while a maximum 6.0 ps group delay is observed at the transparent window of 0.60 THz in type-II MM. The distribution of surface currents and electrical energy reveals that only CeSRR contribute to the transparency window as well as the side-modes in type-I MM, where the current leakage via contact point contributes to the low-frequency side-mode, and the coupled local inductive-capacitive (LC) oscillation in CeSRRs contributes to the high-frequency side-mode. In type-II MM, however, the localized dipolar oscillator of CeSRR contributes to the low-frequency side-mode; while the hybridization of dipole oscillation on eSRR and LC resonance on CeSRR contributes to the high-frequency side-modes. Our experimental findings manifest a new approach to develop THz slow-light devices.
Maternal body mass index moderates antenatal depression effects on infant birthweight
Authors: Petursdottir Maack Heidrun , Skalkidou Alkistis , Sjöholm Anna , Eurenius-Orre Karin , Mulic-Lutvica Ajlana , Wikström Anna-Karin , Sundström Poromaa Inger
Published: April 2019

Obesity and depression are two common medical problems that pregnant women present with in antenatal care. Overweight and obesity at the beginning of the pregnancy, and excessive weight gain during pregnancy, are independent explanatory variables for fetal birthweight and independent risk factors for giving birth to a large for gestational age (LGA) infant. However, the effect of co-morbid depression has received little attention. This study set out to investigate if maternal body mass index (BMI) in early pregnancy moderates antenatal depression effects on infant birthweight. 3965 pregnant women participated in this longitudinal cohort study, where cases (n = 178) had Edinburgh Postnatal Depression Scale (EPDS) score ≥ 17 in gestational week 17 or 32, and remaining women (n = 3787) were used as controls. The influence of maternal BMI and antenatal depressive symptoms on standardized birthweight was evaluated by analysis of covariance, with adjustment for relevant confounders. Depressed women with BMI 25.0 kg/m2 or more gave birth to infants with significantly greater standardized birthweight than non-depressed overweight women, whereas the opposite pattern was noted in normal weight women (BMI by antenatal depressive symptoms interaction; F(1,3839) = 6.32; p = 0.012. The increased birthweight in women with co-prevalent overweight and depressive symptoms was not explained by increased weight gain during the pregnancy. Maternal BMI at the beginning of pregnancy seems to influence the association between antenatal depressive symptoms and infant birthweight, but in opposite directions depending on whether the pregnant women is normal weight or overweight. Further studies are needed to confirm our finding.
Author Correction: Selective Inhibition of Succinate Dehydrogenase in Reperfused Myocardium with Intracoronary Malonate Reduces Infarct Size
Authors: Valls-Lacalle Laura , Barba Ignasi , Miró-Casas Elisabet , Ruiz-Meana Marisol , Rodríguez-Sinovas Antonio , García-Dorado David
Published: April 2019

A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.
Effects of rikkunshito on renal fibrosis and inflammation in angiotensin II-infused mice
Authors: Azushima Kengo , Uneda Kazushi , Wakui Hiromichi , Ohki Kohji , Haruhara Kotaro , Kobayashi Ryu , Haku Sona , Kinguchi Sho , Yamaji Takahiro , Minegishi Shintaro , Ishigami Tomoaki , Yamashita Akio , Tamura Kouichi
Published: April 2019

The underlying pathogenesis of chronic kidney disease involves an activated renin-angiotensin system and systemic inflammation which ultimately develop renal injury. Rikkunshito (RKT) has been reported to exert anti-fibrotic and anti-inflammatory effects through enhancement of ghrelin signaling pathway. In this study, we investigated the effects of RKT on renal fibrosis and inflammation in angiotensin II (Ang II)-induced renal injury model. Ang II-infused mice exhibited hypertension, cardiac hypertrophy, increases in blood urea nitrogen and serum creatinine, moderate albuminuria and renal pathological changes such as mild urinary cast, interstitial macrophage infiltration and modest interstitial fibrosis. RKT had no evident effects on the Ang II-induced renal functional insufficiency and fibrosis, but attenuated renal interstitial macrophage infiltration. In addition, RKT significantly restored the Ang II-induced alteration in the expression of renal fibrosis- and inflammation-related genes such as type 3 collagen, transforming growth factor-β, monocyte chemoattractant protein-1 and interleukin-6. Furthermore, although RKT did not affect the expression of renal ghrelin receptor, an Ang II-induced decrease in renal sirtuin 1 expression, a critical down-stream pathway of the ghrelin receptor, was restored by RKT. These findings suggest that RKT potentially has a renal anti-inflammatory effect in the development of renal injury, and this effect could be mediated by the ghrelin signaling pathway.
Assessment of body adiposity in preterm children at the beginning of school age
Authors: Perenc Lidia , Zajkiewicz Katarzyna , Drzał-Grabiec Justyna , Majewska Joanna , Cyran-Grzebyk Barbara , Walicka-Cupryś Katarzyna
Published: April 2019

In Poland, like in other developed countries, 6.3% of babies are born prematurely. Preterm babies suffer from numerous health issues. The aim of the study was to assess body adiposity in preterm children at the beginning of school age. The study population consisted of 61 children aged 5 to 8 years who had been born preterm. We performed standard anthropometric measurements according to internationally recognized methodology. The following parameters were used: Body Weight (BW), Body Heigh (BH), Waist Circumference (WC), Body Mass Index (BMI), Waist to Height Ratio (WtHR), Triceps Skinfold Thickness (TST), Subscapular Skinfold Thickness (SST), Umbilical Skinfold Thickness (UST), as well as total sum of the above parameters, or the Global Adiposity (GA). The anthropometric measurements were taken according to international anthropometric methodology. All anthropometric parameters for body adiposity were significantly lower in the study population than in the reference system. We found a statistically significant relationship between: the number of fetuses and: UST (p = 0.007) and z-score UST (p = 0.030); combined number of unfavorable perinatal events: and UST (p = 0.013) and z-score UST (p = 0.007), GA (p = 0.038) and z-score GA (p = 0.040). Preterm children who are about to start school have significantly lower values of anthropometric features that characterize their body adiposity. In preterm children at early school age number of fetuses diversifies UST; and combined number of unfavorable perinatal events diversifies UST and GA. It is recommended that more studies are conducted on positively oriented modification of body adiposity in these children, as well as its long term monitoring.
Simulated gastrointestinal digestion of inclusion complexes based on ovalbumin nanoparticles and conjugated linoleic acid
Authors: Visentini Flavia F. , Ferrado Joana B. , Perez Adrián A. , Santiago Liliana G.
Published: April 2019

Ovalbumin delivery system of conjugated linoleic acid resistsin vitrogastrointestinal digestion with high percentages of bioactive retention.
Microfluidic on-demand engineering of exosomes towards cancer immunotherapy
Authors: Zhao Zheng , McGill Jodi , Gamero-Kubota Pamela , He Mei
Published: April 2019

3D printing-based facile microfabrication of a microfluidic culture chip integrates harvesting, antigenic modification, and photo-release of surface engineered exosomes in one workflow, which enables rapid and real-time production of therapeutic exosomes for advancing cancer immunotherapy.
Self-assembly of manganese(i) based thiolato bridged dinuclear metallacycles: synthesis, characterization, cytotoxicity evaluation and CO-releasing studies
Authors: Kumar Udit , Jose Shilpa , Divya Dhanaraj , Vidhyapriya Pitchavel , Sakthivel Natarajan , Manimaran Bala.
Published: April 2019

Manganese(i) based thiolato bridged dinuclear metallacycles were assessed as anticancer agents along with myoglobin assay for CO-releasing studies.
Scrutinizing metal–ligand covalency and redox non-innocence via nitrogen K-edge X-ray absorption spectroscopy
Authors: Lukens James T. , DiMucci Ida M. , Kurogi Takashi , Mindiola Daniel J. , Lancaster Kyle M.
Published: April 2019

A series of nitrogen K-edge XAS data obtained for coordination complexes of diverse transition metals is used to calibrate computational pre-edge peak energies and to afford estimates of metal–ligand covalencies. The approach is extended to probe an inner-sphere aminyl radical ligand.
Photo-responsive liposomes composed of spiropyran-containing triazole-phosphatidylcholine: investigation of merocyanine-stacking effects on liposome–fiber assembly-transition
Authors: Zhang Dawei , Shah Parag K. , Culver Heidi R. , David Sabrina N. , Stansbury Jeffrey W. , Yin Xiaobo , Bowman Christopher N.
Published: April 2019

Assembly-transition study of photo-responsive liposomes composed of spiropyran-containing triazole-phosphatidylcholine (SPTPC).
Enantioselective iridium catalyzed α-alkylation of azlactones by a tandem asymmetric allylic alkylation/aza-Cope rearrangement
Authors: Bai Xue-Dan , Zhang Qing-Feng , He Ying
Published: April 2019

An enantioselective and regioselective α-alkylation of azlactones was developed by iridium catalysis using asymmetric allylic alkylation.
4-Hydroxymethyl-substituted oxazolidinone synthesis by tetraarylphosphonium salt-catalyzed reactions of glycidols with isocyanates
Authors: Toda Yasunori , Tanaka Shoya , Gomyou Shuto , Kikuchi Ayaka , Suga Hiroyuki
Published: April 2019

A tetraarylphosphonium catalyst enables efficient coupling reactions between glycidols and isocyanates to afford 4-hydroxymethyl-substituted oxazolidinones.
Boosting photocatalytic H2evolution on g-C3N4by modifying covalent organic frameworks (COFs)
Authors: Luo Maolan , Yang Qing , Liu Kewei , Cao Hongmei , Yan Hongjian
Published: April 2019

Modifying g-C3N4with covalent organic frameworks (COFs) through imine linkage results in a dramatically enhanced visible-light-driven photocatalytic hydrogen evolution, which reached 10.1 mmol g−1h−1when 2 wt% Pt and triethanolamine were used as co-catalyst and sacrificial agent, respectively, corresponding to an apparent quantum efficiency (AQE) of 20.7% at 425 nm.
Construction of three-dimensional anionic molecular frameworks based on hydrogen-bonded metal dithiolene complexes and the crystal solvent effect
Authors: Yokomori So , Ueda Akira , Higashino Toshiki , Kumai Reiji , Murakami Youichi , Mori Hatsumi
Published: April 2019

Three-dimensional hydrogen-bonded anionic molecular frameworks based on a metal dithiolene complex were constructed with a significant solvent effect.
On the capability of metal–halogen groups to participate in halogen bonds
Authors: Scheiner Steve
Published: April 2019

Halogens in a M–X bond are inhibited from forming a halogen bond but can do so in certain circumstances, with or without a σ-hole.
COSMOplex: self-consistent simulation of self-organizing inhomogeneous systems based on COSMO-RS
Authors: Klamt Andreas , Schwöbel Johannes , Huniar Uwe , Koch Larissa , Terzi Selman , Gaudin Théophile
Published: April 2019

A novel combination of quantum chemistry, statistical thermodynamics and state sampling yields an efficient predictive method for the simulation of complex, self-organizing liquid systems.
Multifunctional Ag@MOF-5@chitosan non-woven cloth composites for sulfur mustard decontamination and hemostasis
Authors: Liu Lin , Ping Enming , Sun Junmei , Zhang Lijuan , Zhou Yunshan , Zhong Yuxu , Zhou Yuanyuan , Wang Yong'an
Published: April 2019

The designed ternary porous composite shows satisfactory sulfur mustard decontamination and hemostasis performance.
Highly active rare-earth metal catalysts for heteroselective ring-opening polymerization of racemic lactide
Authors: Pan Yu , Li Wenqiang , Wei Ning-Ning , So Yat-Ming , Lai Xiaoling , Li Yang , Jiang Kang , He Gaohong
Published: April 2019

Chiral anilido-oxazoline-supported Sc complexes showed outstanding activity (TOFs of up to 2910 h−1) and heteroselectivity in the ring-opening polymerization of rac-LA.
Phenolic profile and effects of acetone fractions obtained from the inflorescences of Calluna vulgaris (L.) Hull on vaginal pathogenic and non-pathogenic bacteria
Authors: Mandim Filipa , Barros Lillian , Heleno Sandrina A. , Pires Tânia C. S. P. , Dias Maria Inês , Alves Maria José , Santos Paulo F. , Ferreira Isabel C. F. R.
Published: April 2019

Fractionated acetone extract of Calluna vulgaris (L.) Hull rich in (−)-epicatechin and (+)-catechin derivatives inhibited vaginal pathogenic bacteria.
Superior Li-ion storage of VS4 nanowires anchored on reduced graphene
Authors: Yang Guang , Wang Huanhuan , Zhang Bowei , Foo Shini , Ma Mingbo , Cao Xun , Liu Jilei , Ni Shibing , Srinivasan Madhavi , Huang Yizhong
Published: April 2019

Kinetic study on VS4 nanowires anchored on rGO for lithium ion storage.
Plastic recovery and self-healing in longitudinally twinned SiGe nanowires
Authors: Shikder Md Ruhul Amin , Ramasubramanian Ajaykrishna , Maksud Mahjabin , Yurkiv Vitaliy , Yoo Jinkyoung , Harris Charles T. , Vasudevamurthy Gokul , Mashayek Farzad , Subramanian Arunkumar
Published: April 2019

This article presents self-healing and mechanical stabilization in longitudinally-twinned SiGe nanowires through segmented elastic and plastic deformation within their grains.
Scalable fabrication of metal–phenolic nanoparticles by coordination-driven flash nanocomplexation for cancer theranostics
Authors: Liu Zhijia , Le Zhicheng , Lu Liejing , Zhu Ying , Yang Chengbiao , Zhao Pengfei , Wang Zhiyong , Shen Jun , Liu Lixin , Chen Yongming
Published: April 2019

Scalable fabrication of highly uniform all-in-one theranostic nanoparticles through a coordination-driven flash nanocomplexation (cFNC) process in a kinetically controlled manner.
Synthesis of multisubstituted arylsulfones via a one-pot, three-component [3 + 3] benzannulation reaction
Authors: Tang Xiang-Zheng , Liang Jie , Zhang Xue-Jing , Sun Raymond Wai-Yin , Yan Ming , Chan Albert S. C.
Published: April 2019

A one-pot, three-component [3 + 3] benzannulation reaction of α,β-unsaturated carbonyl compounds, bromoallylic sulfones, and sodium sulfinates provided multisubstituted arylsulfones with moderate to good yields.
Drawing a clear mechanistic picture for the aggregation-induced emission process
Authors: Zhang Haoke , Liu Junkai , Du Lili , Ma Chao , Leung Nelson L. C. , Niu Yingli , Qin Anjun , Sun Jingzhi , Peng Qian , Sung Herman H. Y. , Williams Ian D. , Kwok Ryan T. K. , Lam Jacky W. Y. , Wong Kam Sing , Phillips David Lee , Tang Ben Zhong
Published: April 2019

Excited-state “double-bond” torsion plays an important role in the nonluminescent behaviour of a stilbene-based twisted isomer.
Fabrication of novel carrageenan based stimuli responsive injectable hydrogels for controlled release of cephradine
Authors: Rasool Atta , Ata Sadia , Islam Atif , Khan Rafi Ullah
Published: April 2019

Kappa carrageenan was used to prepare hydrogels having novel compositions with poly(vinyl alcohol) (PVA) and a crosslinker (3-aminopropyl)triethoxysilane (APTES).
Exploring metabolic biomarkers and regulation pathways of acute pancreatitis using ultra-performance liquid chromatography combined with a mass spectrometry-based metabolomics strategy
Authors: Guo Jiajia , Li Xuesong , Wang Donghong , Guo Yuekun , Cao Ting
Published: April 2019

Acute pancreatitis (AP), as a common kind of pancreas-based inflammatory disease, is accompanied by a serious and abnormal metabolism.
Ruthenium polypyridyl complex-catalysed aryl alkoxylation of styrenes: improving reactivity using a continuous flow photo-microreactor
Authors: Yamaguchi Eiji , Taguchi Nao , Itoh Akichika
Published: April 2019

Previously, we reported the ruthenium polypyridyl complex-catalysed aryl alkoxylation reaction of styrenes with aryldiazonium salts.
Synthesis of sterically hindered 4,5-diarylphenanthrenes via acid-catalyzed bisannulation of benzenediacetaldehydes with alkynes
Authors: Li Yuanming , Yagi Akiko , Itami Kenichiro
Published: April 2019

Acid-catalyzed bisannulation of benzenediacetaldehydes with alkynes provided a rapid access to sterically hindered 4,5-diarylphenanthrenes and multisubstituted phenanthrenes regioselectively.
Highly efficient and very robust blue-excitable yellow phosphors built on multiple-stranded one-dimensional inorganic–organic hybrid chains
Authors: Fang Yang , Sojdak Christopher A. , Dey Gangotri , Teat Simon J. , Li Mingxing , Cotlet Mircea , Zhu Kun , Liu Wei , Wang Lu , ÓCarroll Deirdre M. , Li Jing
Published: April 2019

Strong, multiple-stranded Cu–N bonds lead to a group of highly emissive 1D-CumIm(L) hybrid yellow phosphors with excellent thermal- and photo-stability.
Interfacial transmetallation synthesis of a platinadithiolene nanosheet as a potential 2D topological insulator
Authors: Pal Tigmansu , Doi Shotaro , Maeda Hiroaki , Wada Keisuke , Tan Choon Meng , Fukui Naoya , Sakamoto Ryota , Tsuneyuki Shinji , Sasaki Sono , Nishihara Hiroshi
Published: April 2019

Platinadithiolene nanosheet synthesized by interfacial transmetallation is a possible candidate of a 2D topological insulator at room temperature and an effective catalyst for the electrochemical HER.
Self-assembled propylammonium cations at grain boundaries and the film surface to improve the efficiency and stability of perovskite solar cells
Authors: Fei Chengbin , Zhou Meng , Ogle Jonathan , Smilgies Detlef-M. , Whittaker-Brooks Luisa , Wang He
Published: April 2019

Large size cation (PA) was introduced into the grain boundary and film surface of the 3D perovskite to improve the solar cell efficiency and moisture stability.
DUXAP10 inhibition attenuates the proliferation and metastasis of hepatocellular carcinoma cells by regulation of the Wnt/β-catenin and PI3K/Akt signaling pathways
Authors: Han Kun , Li Chunqi , Zhang Xin , Shang Liang
Published: April 2019

The long non-coding RNA DUXAP10 has been involved in the development, progression, and metastasis in several human cancers, but its biological function and underlying mechanism in hepatocellular carcinoma (HCC) still undetermined. The present study was proposed to explore the effect of DUXAP10 on the growth and metastasis of HCC cells and the potential mechanisms involved. The results showed that DUXAP10 is dramatically elevated in HCC tumor tissues and cell lines. Knockdown of DUXAP10 by DUXAP10 si-RNA significantly inhibited the cell viability, proliferation and induce the apoptosis of HCC cell line. Meanwhile, inhibition of DUXAP10 attenuates the cell migration, invasion, and epithelial–mesenchymal transition (EMT) process. No significant change of JNK MAPK pathway was detected in DUXAP10 siRNA transfected HCC cell lines. The β-catenin and pAkt levels were decreased in the Hep G2+DUXAP10 siRNA and SMMC7721+DUXAP10 siRNA groups, while the activation of Wnt/β-catenin or PI3K/Akt suppressed the inhibition of DUXAP10 siRNA on cell proliferation and migration. Collectively, DUXAP10 plays a critical role in regulating HCC development, potentially by regulating EMT and cell proliferation through the PI3K/Akt and Wnt/β-catenin signaling. Inhibition of DUXAP10 in HCC HepG2 cells could attenuate the EMT and cell proliferation and invasion. Therefore, DUXAP10 might be a promising therapy target to inhibit the growth of HCC.
Using genome editing to engineer universal platelets
Authors: Lawrence Moyra , Mueller Annett , Ghevaert Cedric
Published: April 2019

Genome editing technologies such as zinc finger nucleases, TALENs and CRISPR/Cas9 have recently emerged as tools with the potential to revolutionise cellular therapy. This is particularly exciting for the field of regenerative medicine, where the large-scale, quality-controlled editing of large numbers of cells could generate essential cellular products ready to move towards the clinic. This review details recent progress towards generating HLA Class I null platelets using genome editing technologies for β2-microglobulin deletion, generating a universally transfusable cellular product. In addition, we discuss various methods for megakaryocyte (MK) production from human pluripotent stem cells and subsequent platelet production from the MKs. As well as simply producing platelets, differentiating MK cultures can enable us to understand megakaryopoiesis in vivo and take steps towards ameliorating bleeding disorders or deficiencies in MK maturation in patients. Thus by intersecting both these areas of research, we can produce optimised differentiation systems for the production of universal platelets, thus offering a stable supply of platelets for difficult-to-match patients and providing areas with transmissible disease concerns or an unpredictable supply of platelets with a steady supply of quality-controlled platelet units.
Skywave delay estimation in Enhanced Loran based on Extended Invariance Principle Weighted Fourier transform and Relaxation algorithm
Authors: Zhang Kai , Wan Guobin , Li MinChao , Xi Xiaoli
Published: April 2019

A high precision algorithm is proposed to estimate the Enhanced Loran skywave delay, which is based on an Extended Invariance Principle Weighted Fourier transform and Relaxation (EXIP‐WRELAX) algorithm. It is an innovation on the application of the skywave interference estimation algorithm in the Enhanced Loran receiver. Compared with existing algorithms, this algorithm has higher accuracy and lower computational complexity. Simulation results show that the proposed algorithm reduces the estimated error accuracy from ∼1000 to 50 m. At the same time, accurate search over the entire frequency domain is avoided, which greatly reduces the computational complexity. The algorithm is also proved by the off‐air data.
Study on Physical Account and Value Account of Sea Area Resources
Authors: Wang P , Lin X , Yu Y H
Published: April 2019

Conducting surveys on the status quo of sea area resources, figuring out the basic information about endowment of sea area resources, constructing an accounting standard system for sea area resource assets - value and establishing a physical account and a value account for sea area resource reserve are the foundation for sea area price evaluation and necessary conditions for the perfection of natural resource asset property rights system. This paper analyzes the survey on the status quo of sea area resources in China and the status quo of resource account and value account, brings up a problem that surveys and accountings of sea area resources cannot meet the management requirements of paid utilization of sea area and offers specific suggestions such as carrying out surveys on the space resources of sea area, evaluating the value of resources.
Biological Hydrogen Production from Amphora sp. Isolated from Eastern Coast of Thailand
Authors: Jangiam W , Tongtubtim P , Penjun M
Published: April 2019

The world is finding ways of producing fuel from many sources to replace the fossil fuels. Hydrogen is considered one of the most promising fuels for the future. One biological way of producing hydrogen from solar energy is using photosynthetic microorganisms.The objective of this study is to search for marine algae which produce hydrogen and study the appropriate conditions to produce hydrogen from marine algae. Firstly, the 5 strains of algae were studied the total gas production. Amphora sp. was selected and studied the appropriate conditions to produce hydrogen gas. The first condition, we studied the important factors for marine algae which were present and absent sulfur. The second condition was to find the suitable pH for producing hydrogen which were pH 7, pH 8 and pH 9. The last condition, we studied the optimal light intensity which were 481, 1075 and 2085 lux. The result showed that Amphora sp. can produce hydrogen gas in present sulfur media, pH 8 and light intensity 2085 lux in volume 495.3 ml per 1 L of algae or the average rate of produce hydrogen is 0.798 ml per g of algae per hour.
Traitement des classes II pour les patients au cours de la croissance par gouttières thermoformées : quel protocole ?
Authors: Sabouni Waddah , Eichelberger Alexandre , Des Georges Olivia
Published: April 2019

Introduction : Les classes II squelettiques, fréquemment associées à une rétromandibulie et un surplomb supérieur à 2 mm, entraînent un préjudice fonctionnel et esthétique que le traitement orthodontique se doit de corriger. L’objectif de cet article est de décrire un protocole de traitement par aligneurs, chez le patient en cours de croissance, en fonction de l’importance de la classe II et du stade de maturité de ses vertèbres cervicales. Matériels et méthodes : Au travers de cas cliniques, cet article va présenter trois approches thérapeutiques différentes en fonction du stade de croissance. Résultats : L’étude du potentiel auxologique et la détermination de l’âge osseux (analyse radiologique de la maturation des vertèbres cervicales) vont permettre de déterminer le moment le plus opportun pour traiter la classe II et l’attitude thérapeutique la plus appropriée en fonction du stade de croissance. Discussion : Ce prérequis avant traitement est donc essentiel afin d’adapter un protocole clinique individualisé à chaque patient. En ce sens, les aligneurs sont des dispositifs qui répondent bien à cet impératif, car ils sont personnalisables au vu de la thérapeutique et du plan de traitement envisagés par le praticien. Toutefois, il faut garder à l’esprit qu’une bonne observance est indispensable, quelle que soit la thérapeutique envisagée.
Mütterliche Notfälle: methodisch qualifiziert – schlüssig handeln
Authors: Strauss Alexander , Gräsner Jan-Thorsten
Published: April 2019

Mütterliche Notfälle können den Ausgang von Schwangerschaft und Geburt in erheblichem Maße beeinflussen. Da bedrohliche Situationen in nahezu jeder Lebenssituation und zu jedem beliebigen Zeitpunkt während der Schwangerschaft auftreten können, ist ein Notfalltransport in eine Klinik nicht immer rasch genug möglich. In diesen Fällen hat die Patientinnenversorgung außerhalb einer stationären perinatologischen Einrichtung zumindest zu beginnen. Dabei darf sich der Fokus des Rettungsteams nicht nur auf sich direkt aus der Schwangerschaft ergebende Befunde (z. B. überraschend beginnende oder besonders rasch verlaufende Geburtsbestrebungen, vorzeitiger Blasensprung, Nabelschnurvorfall) konzentrieren, sondern muss ebenso auf Schwangerschaft-koinzidenten Ereignissen (u. a. Akutes Abdomen, Trauma, Uterusverletzung, Anaphylaxie) liegen. Der unvermeidlichen geburtshilflichen Unerfahrenheit des Notarztes gepaart mit den situationsimmanenten Beschränktheiten der Mittel am Einsatzort sind konkrete situationsadaptierte Handlungsschemata entgegenzustellen. Ballastfreies perinatologisches Basiswissen verbunden mit klinischem Pragmatismus markieren hierbei die Eckpunkte ihrer Zweckdienlichkeit: methodisch zu qualifizieren um schlüssig zu handeln.
Tränenwegsspülung – Schritt für Schritt
Authors: Leberkühne Lisanne
Published: April 2019

Das Leitsymptom Epiphora kann neben einer Hypersekretion oder funktionellen Tränenabflussbehinderung auch durch eine anatomische Tränenwegsobstruktion bedingt sein. Hierbei kann eine relative Obstruktion (Stenose) oder absolute Obstruktion (Verschluss) vorliegen. Eine einfache und schnelle Methode zur Diagnostik und Lokalisation oder zum Ausschluss einer Obstruktion ist die Tränenwegsspülung.
Anular Closure RCT – Interpretation der Ergebnisse und Bedeutung für die klinische Entscheidungsfindung im Jahr 2019
Authors: Thomé Claudius
Published: April 2019

Obwohl die lumbale Bandscheibenoperation als häufigster wirbelsäulenchirurgischer Eingriff mit sehr guten klinischen Ergebnissen in Verbindung gebracht wird, besteht ein relevantes Reherniations- und Reoperationsrisiko. Dies gilt insbesondere für Patienten mit hohen Bandscheiben und großen Anulusdefekten, also für bis zu 30 % des Gesamtkollektivs. Um die Rezidivraten nach Mikrodiskektomie zu senken, wurde ein Anulusverschlussimplantat (ACD) entwickelt und kürzlich in einem großen Multicenter-RCT evaluiert. Dieser Übersichtsartikel soll die publizierten Daten und deren Bedeutung für die wirbelsäulenchirurgische Praxis zusammenfassen.

In der Kontrollgruppe des RCT konnte die hohe Rezidivrate von ca. 25 % für diese Hochrisikopopulation nach limitierte Mikrodiskektomie bestätigt werden. Die Reherniationsrate wurde durch das Implantat um die Hälfte gesenkt, so dass bei einer Häufigkeit von Implantat-bedingten Revisionen von unter 3 % auch eine Halbierung der Reoperationsrate erzielt wurde. Die nach harten Kriterien definierte Erfolgsquote betrug ohne Implantat 66 % und mit ACD 76 %. Diese statistisch signifikanten Unterschiede in Reoperations- und Erfolgsraten führten nach 3 Jahren auch zu einem signifikanten Outcomevorteil. Auffällig waren häufige Endplattenveränderungen bei ACD-Patienten, die zwar ohne klinische Konsequenzen blieben, aber eine Langzeitbeobachtung anraten.

Bei der Hochrisikopopulation macht ein Anulusverschluss nach aktueller Datenlage Sinn und verbessert das Operationsergebnis, so dass der Patientenselektion entscheidender Stellenwert zukommt.
Differenzialdiagnose des Bluthochdruckes
Authors: Schricker Severin
Published: April 2019

Die arterielle Hypertonie betrifft etwa jeden dritten Menschen. Sie stellt einen der Hauptfaktoren kardiovaskulärer Morbidität und Mortalität dar. Neben der sehr häufigen multifaktoriellen und polygenen primären oder essenziellen Hypertonie existieren verschiedene Ursachen, welche teilweise kausale Behandlungsansätze erlauben und somit eine große prognostische Relevanz besitzen. Das pathophysiologische Verständnis und die Kenntnis möglicher Differenzialdiagnosen sind für einen rationellen Einsatz der Diagnostik unerlässlich. Der vorliegende Artikel fasst diese zusammen und stellt mögliche Vorgehensweisen zur Bewertung verschiedener Formen der sekundären Hypertonie dar.
Carbon–Oxygen Homocoupling of 2-Naphthols through Electrochemical Oxidative Dearomatization
Authors: Chen Ting , Chen Song , Fu Shaomin , Qin Song , Liu Bo
Published: April 2019

A homocoupling reaction of 2-naphthols with formation of a C–O bond through electrochemical oxidative dearomatization in the presence of catalytic amounts of ferrocene and a ruthenium complex was developed. Mechanistic studies revealed that the reaction might proceed through coupling between two identical radical species. Moreover, a gram-scale experiment was performed to illustrate the potential practicability of this methodology in organic synthesis.
Hitchhiker’s Guide to Reductive Amination
Authors: Podyacheva Evgeniya , Afanasyev Oleg I. , Tsygankov Alexey A. , Makarova Maria , Chusov Denis
Published: April 2019

A comparative study of various widely used methods of reductive amination is reported. Specifically, such reducing agents as H2, Pd/C, hydride reagents [NaBH4, NaBH3CN, NaBH(OAc)3], and CO/Rh2(OAc)4 system were considered. For understanding the selectivity and activity of the reducing agents reviewed herein, different classes of starting materials were tested, including aliphatic and aromatic amines, as well as aliphatic and aromatic aldehydes and ketones. Most important advantages and drawbacks of the methods, such as selectivity of the target amine formation and toxicity of the reducing agents were compared. Methods were also considered from the viewpoint of green chemistry.
Estimation of the Humerus Length by its Proximal Segments: A South Indian Anatomical Study
Authors: Prashanth Kasargod Umesh , Pai Mangala Manohar , Murlimanju Bukkambudhi Virupakshamurthy , Prabhu Latha Venkatraya , Prameela Manoor Dass
Published: April 2019

Introduction To determine the morphometric data of the proximal segments of the humerus in the South Indian population, and to obtain the regression equations that will enable us to predict the whole length of humerus.

Materials and Methods The present study included 166 dried adult human humeri. Their lengths were measured by using the osteometric board. The seven proximal segment lengths of the humeri were assessed by using a digital Vernier caliper (Mitutoyo Corporation 150 mm/6 inch, model number 500-196-20, Kawasaki, Japan).

Results The mean humerus length in the present study was 30.75 ± 2.03 cm on the right side and 30.27 ± 2.28 cm on the left side. The comparison between the right and left sides of the proximal segments of the humerus did not yield statistically significant results (p > 0.05). The present study observed that the relationship between the dimensions of the proximal segments of the humerus and the length of humerus were strong (p = 0.00). The oblique length between the most proximal and distal points over the anatomical neck was the best parameter to predict the length of humerus (the Pearson coefficient was 0.78 for the right side and 0.77 for the left side).

Conclusion The simple regression formulae, which were derived in this study, are helpful in the estimation of the length of the humerus. The formulae can be used in forensic investigations, in which the stature of a person has to be determined and only bone fragments are available. The morphometric data of the present study have implications in archaeological and anthropological studies. The data are enlightening to orthopedicians, when planning reconstructive surgeries of the proximal end of the humerus in the South Indian population.
Anatomical Variation of Hepatic Vascularization: Case Report
Authors: Ruiz Cristiane Regina , Nascimento Sergio Ricardo Rios , Vidsiunas Alex Kors , de Souza Cristiano Cirqueira , Andrades Lilian
Published: April 2019

Anatomical variations in the hepatic arteries and in the celiac trunk are important in liver transplants, laparoscopic surgeries, abdominal radiological interventions, and perforating injuries in the abdomen. The goal of the present report is to describe an abdominal vascular variation observed during a routine dissection in the Anatomy Laboratory of the Centro Universitário São Camilo, São Paulo, state of São Paulo, Brazil, in a male individual. The superior mesenteric artery had its origin in the celiac trunk and originated a right accessory hepatic artery that followed its path all the way to the liver. Several authors described variations in the origin and in the path of the hepatic artery and even created specific classifications. The advance of imaging methods that increase the number of studied individuals, without the need of dissection, aids exponentially the quantifying studies that seek to determine a pattern in the variations present in certain populations. The variations of the hepatic artery, as well as of the celiac trunk, have been extensively described in the literature; however, there is no pattern in the number of variations found both in the celiac trunk and in the regular hepatic artery, what leads to a need of description in each case found.
Interest rates forecasting and stress testing in India: a PCA-ARIMA approach
Authors: Mallick Aswani Kumar , Mishra Alok Kumar
Published: April 2019

In the Basel III era, measuring, managing, mitigating and forecasting interest rate risk has become significant. In the first study of its kind, this paper develops a principal component analysis-based forecasting of interest rates of different maturities and stress testing approach in a univariate auto-regressive integrated moving average (ARIMA) framework in the context of India. Debating the existence of multiple representations of interest rates in the Indian market, the study broke down all the short-term, as well as long-term interest rates to derive the optimal principal component of unique interest rates. These unique interest rates are further exercised to forecast the future interest rates through the ARIMA model. The rolling average method was applied to the recently created Indian volatility index (VIX) to place the stress points. The model performance was examined over this stress point of building multiple scenario analysis. The study found that ARIMA (2-1-1) forecasting model of interest rates produced a better forecast result, both in the case of in-sample and out-of-sample performances as well as in stress periods. From the forecasting results, the study found that the proportionate gain in yield is higher as the maturity increases. By examining the stress period on the basis of eight quarters (2007: Q4 of 2009: Q3) rolling average on Indian volatility Indices, the survey concluded that the Indian economy will reach a stable situation signalled by less volatile interest rates post the second quarter of 2018.
Thermal energy harvester powered piezoresistive pressure sensor system with wireless operation for nuclear reactor application
Authors: Aparna J. , Philip Sebin , Topkar Anita
Published: April 2019

To access the crucial parameters of a nuclear reactor during station blackout condition, we have proposed a concept of using thermal energy harvester powered sensors and instrumentation with wireless operation. To demonstrate this concept, low power electronics comprising a micro electro mechanical system piezoresistive pressure sensor, amplifier, and wireless transmitter was developed for measurement of pressure in a reactor process. The required electrical power for the sensor and instrumentation was derived from the thermal energy produced by the reactor process itself. A thermoelectric generator was used as an energy harvester for converting the heat energy from the process to electrical energy. A power management circuitry was used for the management of the power which was fed to the sensor and electronics. The complete instrumentation was tested in a test loop to demonstrate the operation of thermal energy harvester powered sensor with wireless operation for static and dynamic pressure measurements. Static pressure, increase or decrease of pressure with time and pressure oscillations were measured in a wireless mode using the developed instrumentation. Differential mode measurements were also carried out. The concept of thermal energy harvester powered sensor and instrumentation presented in this paper would be suitable for wireless sensor network of self-powered/thermal energy harvester powered sensors and for wearable devices by operators. An overview of the design and development of the instrumentation and the results are presented in this paper.
Simultaneous measurements of thin film thickness using total internal reflection fluorescence microscopy and disjoining pressure using Scheludko cell
Authors: Ma Tengxiao , Zhou Leping , Du Xiaoze , Yang Yongping
Published: April 2019

This work describes a method for measuring the thin film thickness using total internal reflection fluorescence microscopy, with the use of evanescent wave illumination. The thin liquid film was formed in a hole drilled at the center of a porous plate, which is used for measurement of the disjoining pressure by using the Scheludko cell method. The aim of simultaneous and in situ measurements of thin film thickness and disjoining pressure is to obtain the relationship between them, which is critical for explicitly depicting the thin film profile that determines the interfacial mass and heat fluxes in the thin film region near the triple line. This method can overcome the drawbacks of the optical methods that are insufficient for measuring the thickness of a thin film with curvature. The influence of structural forces formed by tracer nanoparticles seeded in the thin liquid film on the relationship was analyzed. The obtained expression for disjoining pressure vs thin film thickness provides a basis for analyzing the formation, evolution, and stability of the thin liquid film, which is the dominant mechanism of controlling the mesoscopic structure in many transport processes.
Sixth-order schemes for laser–matter interaction in the Schrödinger equation
Authors: Singh Pranav
Published: April 2019

Control of quantum systems via lasers has numerous applications that require fast and accurate numerical solution of the Schrödinger equation. In this paper, we present three strategies for extending any sixth-order scheme for the Schrödinger equation with time-independent potential to a sixth-order method for the Schrödinger equation with laser potential. As demonstrated via numerical examples, these schemes prove effective in the atomic regime as well as the semiclassical regime and are a particularly appealing alternative to time-ordered exponential splittings when the laser potential is highly oscillatory or known only at specific points in time (on an equispaced grid, for instance). These schemes are derived by exploiting the linear in space form of the time dependent potential under the dipole approximation (whereby commutators in the Magnus expansion reduce to a simpler form), separating the time step of numerical propagation from the issue of adequate time-resolution of the laser field by keeping integrals intact in the Magnus expansion and eliminating terms with unfavorable structure via carefully designed splittings.
Broadband photodetection in wide temperature range: Layer-by-layer exfoliation monitoring of WS2 bulk using microscopy and spectroscopy
Authors: Abid  , Sehrawat Poonam , Islam S. S.
Published: April 2019

Exfoliation of bulk WS2 powder has been conducted by ultrasonication, and its layer by layer peeling is monitored by HRTEM, XRD, UV-Vis, and Raman spectroscopy. HRTEM confirms the peeling process and selected area electron diffraction pattern shows the crystallinity of nanosheets which is in accordance with the X-ray diffraction results. Raman and UV-visible spectroscopies further confirm the exfoliation of WS2 to nanosheets having a few layers. A photodetector developed from a few-layered WS2 film is used for photodetection over wide wavelength and temperature ranges. The detector exhibits the highest sensitivity at 635 nm with a value of 382% at 77 K against a value of 138% at 300 K, while the response and the recovery time are ∼78 ms and ∼40 ms, respectively. Temperature, excitation wavelength, and laser power-dependent studies show the threshold limit of its faithful operation. Temperature-dependent photoresponsivity and sensitivity are explained in terms of the carrier–phonon scattering dependent transport mechanism. The scattering cross-section analysis using the density functional theory model reveals that it is the in-plane and out-of-plane acoustic modes that play a key role in carrier transport, rather than the optical phonons. The influence of atmospheric constituents (N2, O2) on detector performance is checked by a successive exposure to dry N2 and ambient air flow. A 14% reduction in photoresponsivity under O2 exposure is observed and suitable analysis is given in terms of O2 induced enhancement of the electron–hole recombination process, leading to a loss of photogenerated carriers. The sensor's cycling performance remains unaffected even after a prolonged exposure in ambient conditions (55% RH), showing its chemical stability even for long-term use.
E × B configurations for high-throughput plasma mass separation: An outlook on possibilities and challenges
Authors: Gueroult Renaud , Zweben Stewart J. , Fisch Nathaniel J. , Rax J.-M.
Published: April 2019

High-throughput plasma separation based on atomic mass holds promise for offering unique solutions to a variety of high-impact societal applications. Through the mass differential effects they exhibit, crossed-field configurations can in principle be exploited in various ways to separate ions based on atomic mass. Here, we review some of the E × B mass filter concepts proposed to date and underline how the practicality of these concepts is conditioned upon the ability to sustain a suitable perpendicular electric field in a plasma for parameters compatible with high-throughput operation. We show that while the limited present predictive capabilities do not make it possible to confirm this possibility, past experimental results suggest that end-electrode biasing may be effective, at least for certain electric field values. We conclude that a better understanding of cross-field conductivity is needed to confirm these results and confirm the potential of crossed-field configurations for high-throughput separation.
Ab initio structure and vibration-rotation dynamics of the formyl and isoformyl cations, HCO+/HOC+
Authors: Koput Jacek
Published: April 2019

Accurate structure and potential energy surface of the formyl and isoformyl cation system, HCO+/HOC+, in its ground electronic state X̃ 1Σ+ have been determined from ab initio calculations using the coupled-cluster approach in conjunction with the correlation-consistent basis sets up to septuple-zeta quality. Both the isomers are confirmed to be linear at equilibrium, with the total energy minimum of HOC+ lying 14 120 cm−1 above that of HCO+ and the HCO+ → HOC+ isomerization energy barrier being 26 870 cm−1 (in the Born-Oppenheimer approximation). The equilibrium structural parameters for HCO+ are estimated to be re(HC) = 1.0919 Å and re(CO) = 1.1058 Å, whereas those for HOC+ are estimated to be re(HO) = 0.9899 Å and re(CO) = 1.1544 Å. The vibration-rotation energy levels were predicted for various isotopologues using a variational approach and compared with the experimental data. For the spectroscopically well characterized formyl cation, the observed vibration-rotation energies and the effective rotational constants are reproduced to within about 2.3 cm−1 and 1.7 MHz, respectively. The role of the core-electron correlation, higher-order valence-electron correlation, scalar relativistic, and adiabatic effects in determining the structure and vibration-rotation dynamics of both the isomers is discussed.
Mass accommodation at a high-velocity water liquid-vapor interface
Authors: Nie J. , Chandra A. , Liang Z. , Keblinski P.
Published: April 2019

We use molecular dynamics to determine the mass accommodation coefficient (MAC) of water vapor molecules colliding with a rapidly moving liquid-vapor interface. This interface mimics those present in collapsing vapor bubbles that are characterized by large interfacial velocities. We find that at room temperature, the MAC is generally close to unity, and even with interfaces moving at 10 km/s velocity, it has a large value of 0.79. Using a simplified atomistic fluid model, we explore the consequences of vapor molecule interfacial collision rules on pressure, temperature, and density of a vapor subjected to an incoming high-velocity liquid-vapor interface.