bluuebunny/crossref_metadata_2025 huggingface dataset:
Experimental Investigation of Inclusion of Various Nanocarbon Black Concentrations on Mechanical Characteristics of Oil-Well Cement Slurries in High-Pressure High-Temperature Conditions
Authors: Ebied Ahmed , Fakher Sherif , Kayed Hatem
Published: February 2025

This study investigates the impact of adding nanocarbon black (NCB) to wellbore cement under high-pressure, high-temperature (HPHT) conditions to enhance its properties for long-term zonal isolation. Four cementitious slurries were prepared in the laboratory using the wet-mixing method, following the American Petroleum Institute standards (API 10B-2 and API 10A). NCB was incorporated as a reinforced nanomaterial in cementitious composites at varying concentrations of 0.05%, 0.1%, and 0.2% by weight of cement (BWOC) into the slurry mix fluid following a specific mixing sequence before the addition of Class-G wellbore Portland cement, which is manufactured via the dry process and commonly used in the oil and gas industry. The study evaluated parameters, such as density, rheology, free fluid (FF), fluid loss (FL), thickening time (TT), compressive strength (CS), tensile strength (TS), porosity, and permeability, following API standards. The results demonstrated that NCB additions slightly increased slurry density and significantly improved rheological properties, with low yield stress at bottomhole circulating temperatures. NCB concentrations of 0.05% and 0.1% reduced free fluid, fluid loss, and thickening time while enhancing the cement sheath's compressive and tensile strength, simultaneously reducing its porosity and permeability. Moreover, the improved early compressive strength development indicated accelerated cement hydration reactions due to incorporating NCB. The study found that 0.1% NCB was the optimal concentration, enhancing mechanical properties and operational efficiency by reducing wait-on-cement time and costs while improving wellbore integrity. However, higher NCB concentrations required careful dispersion to prevent nanoparticle agglomeration. Overall, NCB significantly enhanced cement sheath characteristics under HPHT conditions.
Advances in engineered T cell immunotherapy for autoimmune and other non-oncological diseases
Authors: Huang Qiaolin , Zhu Xiaojian , Zhang Yicheng
Published: February 2025

Adoptive immunotherapy using engineered T cells expressing chimeric antigen receptors has shown remarkable success in treating patients with hematological malignancies. However, realizing broader therapeutic applications of engineered T cells in other diseases requires further exploration in clinical investigations. In this review, we highlight recent advances in the engineering of T cells in non-oncology areas, including autoimmune and inflammatory diseases, infections, fibrosis, hemophilia, and aging. Chimeric antigen receptor immunotherapy has shown good outcomes in non-oncology areas, but many challenges remain in improving its safety and efficacy and and expanding its application to the treatment of non-oncological diseases.
Sol–gel synthesis of silicon oxide (SiO2) nanoparticles: exploring gas sensing and photocatalytic applications
Authors: Sonawane Laxmi D. , Mandawade Abhinay S. , Gite Anil B. , Shinde Sarika D. , Patil Ganesh E. , Nikam Latesh K. , Goswami Vishal H. , Bhise Ramesh B. , Sarawade Pradip B. , Shinde Mahendra S.
Published: February 2025

In this research, silicon oxide (SiO2) nanoparticles (NPs) were synthesized using the sol–gel method. The synthesized materials were characterized through various techniques. Fourier transform infrared spectroscopy (FTIR) revealed the absorption band corresponding to Si–O–Si bonds. Ultraviolet–visible (UV–Vis) spectroscopy analysis indicated a band gap energy of 5 eV. X-ray diffraction (XRD) analysis displayed a broad peak, confirming the amorphous nature of the material. Field emission scanning electron microscopy (FESEM) further demonstrated a spherical morphology of the SiO2 NPs. The photocatalytic degradation of MB dye using SiO2 NPs has been examined, revealing promising and improved degradation properties. Even a small amount of SiO2 NPs achieved around 69.20% degradation of MB within 240 min, with the rate constant for the material being 0.001 min−1. The gas sensing properties of the SiO2 NPs were tested on domestic gas sensor units for different gases, including ethanol, methanol, CO2, LPG, H2S, NH3, O2, and Cl2, at temperatures ranging from room temperature to 300 °C. Among these materials, SiO₂ NPs displayed the strongest response to H₂S gas, showing outstanding gas-sensing performance at a concentration of 100 ppm. The response time was 18 S, with a quick recovery time of approximately 22 S.

Graphical Abstract
Beyond minutiae: inferring missing details from global structure in fingerprints
Authors: Searston Rachel A. , Thompson Matthew B. , Robson Samuel G. , Tangen Jason M.
Published: February 2025

Visual inference involves using prior knowledge and contextual cues to make educated guesses about incomplete or ambiguous information. This study explores the role of visual inference as a function of expertise in the context of fingerprint examination, where professional examiners need to determine whether two fingerprints were left by the same person, or not, often based on limited or impoverished visual information. We compare expert and novice performance on two tasks: inferring the missing details of a print at an artificial blank spot (Experiment 1) and identifying the missing surrounds of a print given only a small fragment of visual detail (Experiment 2). We hypothesized that experts would demonstrate superior performance by leveraging their extensive experience with global fingerprint patterns. Consistent with our predictions, we found that while both experts and novices performed above chance, experts consistently outperformed novices. These findings suggest that expertise in fingerprint examination involves a heightened sensitivity to gist, or global image properties within a print, enabling experts to make more accurate inferences about missing details. These results align with prior research on perceptual expertise in other expert domains, such as radiology, and extend our understanding of scene and face recognition to fingerprint examination. Our findings show that expertise emerges from an ability to combine local and global visual information—experts skillfully process both the fine details and overall patterns in fingerprints. This research provides insight into how perceptual expertise supports accurate visual discrimination in a high-stakes, real-world task with broader implications for theoretical models of visual cognition.
Abdominal pseudocyst: a rare complication of ventriculoperitoneal shunt
Authors: Al-Mahrouqi Omar , Al-Saadi Tariq
Published: February 2025

Like any other surgical intervention, ventriculoperitoneal shunt (VPS) insertion is associated with multiple complications including bleeding, shunt infection, and shunt malfunction. Additionally, other complications involve the gastrointestinal tract, such as CSF pseudocyst or abdomen pseudocyst (APC) formation, have also been reported. The APC inhibits cerebrospinal fluid (CSF) absorption and causes shunt malfunction. Differential diagnosis might be difficult since APC can mimic other cystic abdominal diseases. This article aims to provide an updated review that summarize the most relevant findings available in the literature. This review can help clinicians in better understanding the clinical characteristics of this complication in order to develop a comprehensive approach that is associated with a lower incidence and recurrence rate of APC. Accurate history taking, precise clinical examination of signs and symptoms, abdominal imaging, and a high index of suspicion are key components of an APC diagnosis. Therefore, understanding predisposing factors and clinical features of such distinctive complication is essential for the adequate management of patients. Abdominal pseudocyst formation at the distal end of VPS can result in both features of shunt malfunction and abdominal signs and symptoms. Post-VPS APC, whenever suspected, should be assessed appropriately by imaging. The treatment of APC ranges from shunt removal and external drainage to various forms of shunt repositioning or conversion, and treatment decisions often depend on individual patient characteristics and surgeon preference.
“Spontaneous epidural hematoma in a pediatric patient following pansinusitis: a case report and review of the literature”
Authors: Nazarpour Shahin , Qoorchi Moheb Seraj Farid , Sharifzadeh Khavari Seyed Morteza , Seadghat Mehran , Abouei Mehrizi Mohammad Ali
Published: February 2025

Background

Spontaneous epidural hematoma commonly occurs in patients who have coagulopathy, vascular tumors, and vascular malformations. The association between this entity and maxillofacial infection is rare.

Case Presentation

A 17-year-old male patient presented to our emergency with a decreased level of consciousness. The patient had a history of nasal discharge and fever for about four days. The brain Computed tomography scan revealed a hematoma that was treated with craniotomy. The hematoma culture was positive for staphylococcus aureus, so antibiotic therapy was started for the patient and continued for six weeks. All the symptoms were fully recovered and the patient was discharged without any neurological deficits. Although spontaneous epidural hematoma following craniofacial infection is rare, prompt imaging and hematoma evacuation have been found with higher rates of favorable outcomes and Markley decreased mortality.

Conclusion

Distinguishing between hematoma and cerebral abscess is slightly difficult. However, consideration of surgery facilitates reaching a reliable diagnosis and treatment.
Detection to false data for smart grid
Authors: Zheng Jian , Ren Shumiao , Zhang Jingyue , Kui Yu , Li Jingyi , Jiang Qin , Wang Shiyan
Published: February 2025

False data injection attack in smart grid might does not launch interference and attack behaviors, so that this attack is difficult found. To address this, this paper proposed a conformal neural network detection method being sensitive to false data. Firstly, using the conformity scores calculated by the mathematical probability to identify the false data. Then, the neural network learns a boundary separating false data and normal data on the conformal region yielded by the conformity scores. Finally, experiments on simulated and real datasets indicate that the proposed method obtains 0.9738 detected accuracy, and the sensitivity to false data reaches 0.9387, defeating against the competitors, moreover, the proposed method does not exhibit exponential detection time as data volume augments. We demonstrate that evaluating the consistency between the data does not rely on data distributions and the operation status in this real-time system like smart grids, since conformity scores can calculate the mathematical probability following the same data distribution. The boundaries learned from conformal regions are independent of data distribution and the information of operation status in smart grids. This evaluation manner of data consistency and that of boundary learning are equally applicable to the identification and separation of those false data injected into other real-time systems.
Case report: a rare case of hereditary colorectal cancer and brain tumor with café au lait spots in a child: constitutional mismatch repair deficiency (CMMRD) syndrome
Authors: Khurshid Zubair , Shaikh Mishraz , Elkadi Tarek Talaat Harb
Published: February 2025

Background

Colorectal carcinoma (CRC) is rarely seen in the pediatric population. Hereditary cancers due to mismatch repair deficiency cause colorectal, brain, hematological malignancies, and other tumors in early childhood.

Case presentation

We present an 11-year-old boy who presented with colorectal cancer and brain tumor due to constitutional mismatch repair deficiency syndrome with a family history of sibling deaths due to brain tumors.

Conclusions

Hereditary cancers arising due to mismatch repair gene mutations cause early colorectal and brain cancers in children. The members of such families should be genetically screened for any mutations.
Exploring and detecting predictors associated with survival and mortality of cervical cancer patients: a 10-year retrospective study
Authors: Muneeha Shaba , Chaudhary Raushan Kumar , Shetty Vijith Vittal , Patil Soumya , Mateti Uday Venkat
Published: February 2025

Background

Cervical cancer is the 4th most prevalent cancer among females globally. In India, approximately 123,907 women are diagnosed with cervical cancer every year, leading to 77,348 deaths annually. However, Indian healthcare system lacks the sufficient information regarding the factors influencing survival and mortality among cervical cancer patients at regional levels. Thus, we aimed to identify the predictors associated with survival outcomes and mortality rates among cervical cancer.

Methods

A retrospective cohort study was conducted over 8 months at a tertiary care hospital where 10-year (January 2013–December 2022) data of cervical cancer patients were analyzed from medical record department (MRD). Telephonic interviews were carried out with patients or patient parties to know the survival status of patients. The data was analyzed using descriptive statistics, Kaplan–Meier curve, log-rank test and Cox regression.

Results

Out of 330 cervical cancer patients, majority (64.24%) were > 50 years of age followed by 35.76% were < 50 years. Most of the patients had abnormal body mass index (BMI) (46.96%), postmenopausal stage (75.76%), stage II cancer (43.03%), histologically poorly differentiated grade (47.88%) and squamous cell carcinoma (87.88%), with radiation plus chemotherapy being popular treatment choice (48.79%) and with the overall mean age of 56 years. Age, BMI, menopause, stage of cancer, histological grades and types of treatment were found to be significant predictors (p < 0.05) of survival among cervical cancer patients. Using cox regression analysis, advanced age (age > 50 years: hazard ratio (HR): 1.82), underweight (BMI < 18.5: HR:1), postmenopause (HR:1), advanced stage of cervical cancer (Stage I, Stage II, Stage III, Stage IV: HR:1, HR:2.78, HR:10.08, HR:20.81), poorly differentiated cervical cancer (HR:1.70), radiation therapy (HR:4.86), chemotherapy (HR:6.55) or chemoradiation therapy (HR:3.31) and surgery plus chemotherapy (HR: 4.55) were identified to be significant predictors of mortality among cervical cancer patients.

Conclusion

We conclude that the 5- and 10-year survival rates for cervical cancer patients were found to be 51.2% and 42.9%, respectively. Advanced age, underweight, postmenopausal status, advanced cancer stage, poor cancer cell differentiation and chemotherapy-based treatment were significant predictor of mortality and vice-versa for survival which might guide clinicians and policymakers in making informed clinical decisions to combat cervical cancer.
Patient-Reported Outcomes: Comparing Functional Avoidance and Standard Thoracic Radiation Therapy in Lung Cancer
Authors: Poiset Spencer J. , Lombardo Joseph , Castillo Edward , Castillo Richard , Jones Bernard , Miften Moyed , Kavanagh Brian , Dicker Adam P. , Boyle Cullen , Simone Nicole L. , Movsas Benjamin , Grills Inga , Rusthoven Chad G. , Vinogradskiy Yevgeniy , Wilson Lydia
Published: February 2025

PURPOSE

Novel methods generate functional images using image processing techniques combined with four-dimensional computed tomography (4DCT) data (4DCT-ventilation). 4DCT-ventilation was implemented in a phase II, multicenter functional avoidance clinical trial. The work compares functional avoidance patient-reported outcomes (PROs) against historical standards.

METHODS

Patients with locally advanced lung cancer undergoing curative-intent chemoradiation were accrued. 4DCT-ventilation imaging was generated and functional avoidance treatment plans created reduced dose to functional lung. PRO instruments included Functional Assessment of Cancer Therapy Lung questionnaire and accompanying subscales (including the Trial Outcome Index [TOI]), EuroQol-5 Dimension (EQ-5D), and EQ-Visual Analog Scale (EQ-VAS). The average change from baseline and percentage of clinically meaningful declines were calculated. We compared results against PROs from RTOG 0617 and PACIFIC trial data using Student t-tests and chi-square tests.

RESULTS

Fifty-nine patients completed baseline PRO surveys. The median age was 65 (44-86) years, non–small cell lung cancer comprised 83%, and median dose was 60 Gy in 30 fractions. The percent of patients with clinically meaningful decline in FACT-TOI at 12 months was 47.8% for RTOG 0617% and 26.8% for functional avoidance (
P
= .03). The functional avoidance cohort demonstrated a significantly (
P
= .012) higher change in EQ-VAS score at 12 months (9.9 ± 3.3; average ± SE) compared with the PACIFIC cohort (1.6 ± 0.6).

CONCLUSION

The current work demonstrates improved PROs from a phase II functional avoidance trial in certain subscales (FACT-TOI and EQ-VAS) compared with PROs from seminal studies (RTOG 0617 and PACIFIC). The presented data support investigation of 4DCT functional avoidance in a phase III setting.
Development of a Dermal Nanoemulsion with Antioxidants Derived from Rice Residues Using an HLD Theory Approach
Authors: Vargas-Escobar Paola , Quintero-Rincón Patricia , Flórez-Acosta Oscar
Published: February 2025

Agricultural waste, such as rice straw, has become increasingly valuable as biocomposites in various industries. For cosmetic and pharmaceutical sectors, these biocomposites have improved active substance incorporation and waste reduction, which is pivotal for mitigating environmental impact. This study reports the encapsulation of a protein derivative derived from rice straw within a nanoemulsion for skin care applications, emphasizing stability and efficacy. Protein hydrolysates were produced by extracting proteins in an alkaline medium, followed by precipitation at the isoelectric point. The hydrolysates were enzymatically treated with Alcalase® at 80 °C and pH 10 for 45 min to generate antioxidant-rich formulations. Utilizing Hydrophilic-Lipophilic Deviation (HLD) theory, oil-in-water (O/W) emulsions were formulated by adjusting variables to achieve an HLD near zero. Sunflower oil and surfactants were combined, stirred at 70 °C, and homogenized using a rotor–stator. The final formulation's stability and permeability were evaluated through fluorescence microscopy, particle size analysis, zeta potential measurements, and accelerated stability assays. Nanoemulsion ENE37 showed high stability with 47.25 nm size, PDI 0.21, and excellent dispersion, maintaining integrity without phase separation. Hydrolyzed protein into ENE37 (NE37-HP) improved stability, increasing zeta potential and preventing aggregation while maintaining structure without phase inversion. NE37-HP exhibited shear-thinning behavior and good diffusion capacity, achieving 20.14 μg/cm2.h. The HLD theory and ternary diagrams are valuable methodological tools for formulating stable nanoscale emulsions. Additionally, this dosage form, containing protein hydrolysates derived from rice straw, demonstrated potential for adequate dermal absorption in humans.

Graphical Abstract
Sex Differences in the Association Between Thyroid Hormone Sensitivity and Cardiovascular-Kidney-Metabolic Syndrome
Authors: Jiang Lanxuan , Zhou Liyuan , Liu Jia , Wang Ying , Wang Guang
Published: February 2025

Background

The relationship between thyroid hormone sensitivity and cardiovascular-kidney-metabolic (CKM) syndrome remains unclear. This study aims to investigate the association between thyroid hormone sensitivity and the early-stage of CKM syndrome, with a specific focus on the moderating effects of sex and age.

Methods

A total of 8391 euthyroid participants were enrolled in this cross-sectional study. Data on metabolic parameters and thyroid hormone levels were collected. Thyroid hormone sensitivity indices-thyroid feedback quantile index (TFQI), thyroid-stimulating hormone index (TSHI), thyrotrophic thyroxine resistance index (TT4RI), and free T3 to free T4 ratio were calculated. Logistic regression models and restricted cubic spline regression (RCS) were used to analyze the association between thyroid hormone sensitivity and stage 2 of CKM syndrome stratified by sex and age.

Results

In men, the higher TFQI, TSHI, and TT4RI values were significantly associated with increased risks of stage 2 of CKM syndrome. In women, these associations were weaker but still present, particularly for TSHI. RCS analysis also showed that the risk of CKM syndrome tended to increase with decreasing thyroid hormone sensitivity in men. However, these associations in women were not as significant as in men. Age-stratified analysis revealed that older men (>50 years) showed a stronger correlation between thyroid hormone sensitivity and CKM syndrome compared to women.

Conclusion

This study demonstrated that impaired thyroid hormone sensitivity was significantly associated with the early-stage of CKM syndrome, particularly in older men. These findings provide the evidence of the importance of thyroid hormone sensitivity in CKM syndrome, especially in men over the age of 50.
Cognitive Risk Stratification Score in Middle-aged and Older Adults With Type 2 Diabetes: A Cross-Sectional Study
Authors: Zhang Jinghua , Tam Wilson Wai San , Lu Jinhua , Chen Junjie , Kusuyama Joji , Dong Yanhong , Yap Xin Yi , Zhou Wentao , Wang Na , Yeo Hui Nan , Lee Frena Jia Sy , Wu Vivien Xi
Published: February 2025

Context

Cognitive impairment (CI) affects approximately 45% of middle-aged and older adults with type 2 diabetes mellitus (T2DM) globally. Although formal comprehensive neuropsychological tests are the gold standard for diagnosing CI, they are often time-intensive and may not be feasible in primary care.

Objective

This study aimed to develop and validate a novel risk stratification score (RSS) to rapidly and comprehensively predict CI risk among middle-aged and older adults with T2DM, offering a streamlined alternative in clinical practice.

Methods

A cross-sectional study was conducted from July 2023 to February 2024 in a primary care polyclinic in Singapore's western region. Participants aged between 40 and 85 diagnosed with T2DM (n = 150) were included in a convenience sampling. The primary outcome was CI status, which was assessed using formal neuropsychological tests, including the Montreal Cognitive Assessment (MoCA).

Results

CI was identified in 49.3% of participants (n = 74). The RSS, incorporating the MoCA, diastolic blood pressure, and Short Physical Performance Battery, demonstrated excellent discrimination, achieving an area under the receiver operating characteristic curve of 0.802 (P < .001). With an optimal cutoff of 0.3, the model showed a sensitivity of 63.5% and specificity of 86.8%, effectively differentiating high- and low-risk CI groups.

Conclusion

RSS in clinical practice, exemplified by the Integrated Metabolic Cognitive Risk Stratification Pathway, is a promising tool for rapid CI risk assessment in primary care. Its robust predictive accuracy and ease of use support its application for early intervention in middle-aged and older adults with T2DM. Future studies should validate its use longitudinally and across diverse populations to enhance generalizability.
Gamificação do aplicativo Strava e o engajamento dos corredores do grupo Sun Runners
Authors: Wilbert Daniela Morgana , Viana Luciane Pereira
Published: February 2025

Este estudo teve como objeto um grupo de atletas amadores que utilizam o aplicativo Strava para o automonitoramento, tendo como objetivo identificar como a gamificação utilizada no aplicativo Strava consegue engajar os corredores do grupo Sun Runners a fazerem suas atividades físicas e melhorarem suas performances. Utilizou-se uma abordagem descritiva e qualitativa, com a aplicação de um questionário aos 64 corredores do grupo e uma análise das funcionalidades do aplicativo Strava. Os resultados mostram que os recursos de segmentos, treinamento, prêmios, mapas e desafios são os mais eficazes para ajudar os atletas a atingirem suas metas de treino. Além disso, as funcionalidades de feedback e a análise de desempenho contribuem para a melhoria contínua da performance dos corredores. Conclui-se que a gamificação no Strava estimula o engajamento dos usuários na corrida e promove a busca pela superação pessoal.
Práticas de gestão de custos no cenário brasileiro
Authors: Ribeiro Sílvio Paula , Tsunoda Macla Toyoko , Tisott Sirlei Tonello , Brandt Eloi Almiro , Carraro Nilton Cezar
Published: February 2025

Um dos atributos para que as empresas se mantenham competitivas no mercado global é a gestão de custos. Portanto, o estudo teve como objetivo descrever o cenário brasileiro da produção científica sobre práticas de gestão de custos nas empresas. Foi realizada pesquisa bibliométrica com 16 artigos científicos obtidos nas bases scielo, scopus e spell. Os resultados indicam que há baixo número de publicações, falta de continuidade nas pesquisas, poucos autores pesquisando o tema e ausência de abordagem teórica nos estudos. Vale ressaltar que todas as pesquisas foram publicadas em periódicos com boas avaliações, sendo 6 (seis) deles em periódicos avaliados com indicador “A” no Qualis-Capes.
Το μοναχικό παιχνίδι ως μέσο κοινωνικοποίησης και αυτονομίας του παιδιού προσχολικής ηλικίας
Authors: Αθανασοπούλου Άννα
Published: February 2025

Κυρίαρχη θέση στις αλληλεπιδράσεις του παιδιού έχει το παιχνίδι, ελεύθερο ή οργανωμένο. Ιδιαίτερα το ελεύθερο παιχνίδι προάγει την αποκέντρωση της σκέψης δημιουργώντας καταστάσεις προβληματισμού, οι οποίες ενθαρρύνουν την αποδοχή και τον σεβασμό του άλλου, αλλά και του εαυτού. Αυτό όμως που κάνει το παιδί να διαφέρει ως οντότητα μέσα στην ομάδα είναι το πώς ερμηνεύει και αντιλαμβάνεται την επιρροή των άλλων στη δική του πορεία. Έτσι, ακόμη κι αν ένα παιδί εμπλέκεται σε μοναχικό παιχνίδι βρίσκεται σε μια διαδικασία αξιολόγησης όσων βλέπει, μέχρι να φτάσει στο σημείο να εμπλακεί ενεργά σε αλληλεπίδραση με τους άλλους. Σκοπός της παρούσας έρευνας είναι η μελέτη του μοναχικού παιχνιδιού μέσα στα πλαίσια της ομάδας των συνομηλίκων ως μέσο κοινωνικοποίησης και αυτονομίας του παιδιού προσχολικής ηλικίας. Μέσω συμμετοχικής παρατήρησης που έλαβε χώρα σε τέσσερα νηπιαγωγεία σε προάστια του Παρισιού, και συνεντεύξεων με νηπιαγωγούς, αναδικνύεται ότι η ικανότητα του παιδιού να δραστηριοποιείται και να παίζει ελεύθερα μόνο του μέσα στο χώρο του νηπιαγωγείου, παρουσία άλλων ατόμων, του παρέχει τη δυνατότητα να πάρει πρωτοβουλίες και να δράσει αυτόνομα κάνοντας τις δικές του επιλογές. Έπειτα από ποιοτική ανάλυση πρωτογενούς υλικού, τα αποτελέσματα δείχνουν ότι τα παιδιά εμπλέκονται σε μοναχικό παιχνίδι για να συγκεντρωθούν στη δραστηριότητα που έχουν επιλέξει και να εξυπηρετήσουν τις προσωπικές τους ανάγκες, ενώ παράλληλα αναπτύσσουν κοινωνικές δεξιότητες διαπραγματεύοντας το ρόλο τους και τον χώρο τους μέσα στην ομάδα των συνομηλίκων.
The dynamics of financial performance and market performance in the context of Indian banking industry
Authors: Sar Ashok , Panigrahi Kshirod
Published: February 2025

Background This study aims to gain insight into the effect of banks’ financial performance on their market performance. We conceptualized the research subject on the assumption that the financial performance of an organization is the most important criterion for triggering movement in its stock price. We explored various models and parameters to evaluate financial performance of banks and found CAMELS being one of the most comprehensive and appropriate model. We considered share price growth of banks to measure their stock market performance Methods We collected financial and stock market data pertaining to 32 listed Indian banks for the period 2018 to 2022. The study has employed multiple linear regression analysis of panel data for evaluating the relationship between independent and dependent variables. We adopted panel regression for data analysis and used the Prais- Winsten regression with panel corrected standard errors, as the data suffers from contemporaneous cross-sectional correlation. Results The results show that net non-performing assets, net interest margins, and return on capital have a significant negative impact on share price growth. The capital adequacy ratio and the current and savings account deposit ratios have a positive insignificant impact. The liquid asset-to-total asset ratio has a negative, insignificant impact. The coefficient of determination indicates that the share price growth of banks is more dependent on other factors which are not included in the regression analysis of this study. Conclusion This study helps investors and bankers understand the limited impact of financial parameters on banks’stock prices and to look for other parameters which explain the stock price movement better.
Fuzzy Set Theory Applied on Autometrized Algebra
Authors: Tilahun Gebrie Yeshiwas
Published: February 2025

This paper introduces fuzzy subalgebras of autometrized algebras and studies their properties. Also, we present fuzzy ideals of autometrized algebras and provide examples to illustrate our findings. We examine the homomorphisms of both the images and the inverse images of fuzzy subalgebras and ideals. Furthermore, we introduce fuzzy congruences on autometrized algebras. We prove that in normal autometrized algebra, the set of all fuzzy ideals is in one-to-one correspondence with the set of all fuzzy congruences.
Protocol for a Realist Review of Pathways to Lung Cancer Diagnosis in LMICs: A Focus on Contextual Factors and Application to the South African Healthcare System (ECLiPSA)
Authors: Nyawira Githaiga Jennifer , Murphy Conor F. , Graham Joshua , Day Sarah , Khurana Vedika , Khosaf Raghad , Brady Bates Oisin , Innocent Besigye Kabahena , Weakliam Professor David , Mash Professor Bob , Redmond Professor Patrick
Published: February 2025

Background Lung cancer is a leading cause of cancer-related mortality globally, with diagnostic delays in Low- and Middle-Income Countries (LMICs) often resulting in late-stage detection and poor outcomes. A comprehensive understanding of the pathways to diagnosis, and the contextual factors that shape them, is essential to improving early detection in these settings. This protocol describes a realist review to examine how patient, healthcare provider, and system-level contexts influence pathways to lung cancer diagnosis, focusing on barriers and facilitators. Methods The review will employ a realist approach to develop, test, and refine theories on how diagnostic pathways operate within LMIC contexts. Specifically, we will explore how contextual factors at the patient, healthcare provider, and system levels interact to influence mechanisms that lead to timely or delayed diagnosis. The initial programme theory (IPT) will be developed through a scoping review and stakeholder consultation, with iterative refinement as evidence is synthesised. Data from multiple sources, including peer-reviewed literature, grey literature, and stakeholder input, will be extracted, coded, and synthesised to identify context-mechanism-outcome (CMO) configurations. The review will adhere to RAMESES standards for realist reviews. Outcomes The review will generate CMO configurations explaining the function of lung cancer diagnostic pathways in LMICs, with a particular focus on South Africa as a case context. Findings will inform strategies and policies to improve early diagnosis by addressing key contextual barriers and enhancing facilitators. Stakeholder engagement will ensure findings are applicable and relevant to local healthcare settings. Conclusion This review aims to provide actionable insights into lung cancer diagnostic pathways in LMICs, enabling the development of targeted interventions to reduce delays, promote early diagnosis, and ultimately improve patient outcomes, with an emphasis on translating findings to South African healthcare contexts.
Protocol for a scoping review to explore governance for national hip fracture clinical audits
Authors: Brent Louise , Ojeda-Thies Cris , Fitzpatrick Fidelma , Merriman Niamh , Byrne Elaine
Published: February 2025

Background Hip Fractures are serious injuries leading to increased morbidity and mortality. The global incidence of hip fracture is rising. National hip fracture audits facilitate improvements in patient outcomes and care quality. There is a wealth of literature regarding hip fracture care, evidence-based standards, use of registry/clinical audit data for improvement, benchmarking and outcomes. There is however a gap in the literature for describing how to establish the governance for a national hip fracture audit. Objective This scoping review aims to identify the core governance components for national clinical audits (NCAs) of hip fractures. Methods The Joanna Briggs Institute guidance will be used in conducting the review and Preferred Reporting Items for Systematic Reviews extensions for Scoping Reviews (PRISMA-ScR) guidance for scoping reviews will be followed. has been used. Articles published in English, between 1988–2024 and indexed in MEDLINE (Ovid), Embase (Elsevier) and CINAHL (EBSCOHost) will be included in this review. Two reviewers will independently screen the articles, with any disagreements resolved by a third reviewer. Data extraction will be conducted by two reviewers and shared with external stakeholders to ascertain whether there is documentation or reports that were missed and preliminary analysis will be shared to validate the data we have extracted. The results will be disseminated widely through publication in an international peer reviewed journal and through the Global Fragility Fracture Network (FFN) Hip Fracture Audit Special Interest Group. Conclusions By identifying the core components for the governance of NCAs for hip fracture it is hoped that application of these components will support the existing NCAs for hip fracture to enhance their current governance and aid in the establishment of NCAs in the future.
The Skin as a Window to Diabetes Mellitus: Manifestations, Complications and Clinical Insights
Authors: Kutaj Aleksandra , Adamowicz Zuzanna
Published: February 2025

Introduction and purpose
Diabetes mellitus (DM) is a chronic disease with a growing global prevalence, affecting 8.3% of adults, with a significant proportion remaining undiagnosed. The condition impacts multiple organ systems, including the skin, where manifestations often represent the earliest and most visible signs of metabolic dysregulation. Skin changes associated with DM, such as acanthosis nigricans, xerosis, diabetic dermopathy  and necrobiosis lipoidica, not only highlight underlying metabolic disturbances but also provide valuable non-invasive tools for monitoring glycemic control and disease progression.

Material and methods
This study is based on a comprehensive review of recent literature focusing on the skin manifestations and clinical implications of diabetes mellitus -related skin changes.
Description of the State of KnowledgeHyperglycemia disrupts normal cellular processes in the skin, leading to impaired wound healing, increased oxidative stress, and inflammation. These pathological changes contribute to various dermatological symptoms, including xerosis, pruritus, erythema, and fibrosis. Skin changes, such as diabetic dermopathy, necrobiosis lipoidica, and recurrent fungal infections, are not only indicators of DM but also reflect glycemic control and disease severity. These manifestations can signal undiagnosed diabetes or poorly controlled blood glucose levels, offering a non-invasive method for disease monitoring.
ConclusionsSkin manifestations are vital diagnostic tools in diabetes care, providing early indications of metabolic imbalances and poor glycemic control. Their presence underscores the need for timely interventions, including lifestyle modifications, pharmacological treatments, and patient education. Dermatological assessments, particularly in resource-limited settings, offer an accessible approach to monitoring therapy effectiveness and predicting complications.
De Dr. Jekyll a Mr. Hyde: as obras de Gilberto Freyre e sua trajetória intelectual
Authors: Cazetta Felipe
Published: February 2025

Gilberto Freyre foi sociólogo fundamental na compreensão da formação
da sociedade brasileira, suas contradições e complexidade. Todavia, por possuir
produção intelectual longeva, alguns de seus textos são polêmicos provocando ruídos
na recepção acadêmica. Diante disso, pesquisadores se debruçam por organizar em
etapas a produção de Freyre. O objetivo deste artigo é oposto, por justamente buscar
compreender não os intervalos ou etapas, mas a continuidade na obra de Gilberto
Freyre, desde de seu período de formação nos Estados Unidos, até sua associação
ao regime salazarista. Assim, busca-se compreender suas nuances, contradições e
permanências, tal como seus objetivos, paixões e influências intelectuais.
Hacer a los españoles lo que ellos hacen con nosotros”: represalia, canje y regularización de la guerra, Colombia 1819- 1820
Authors: Cardona Zuluaga Patricia
Published: February 2025

A través del análisis de fuentes primarias, este texto estudia la represalia y la
vindicación en la regularización de la guerra y en la reglamentación de estrategias
(como el canje de prisioneros) para mitigar los desmanes de una guerra sin límites
como la Guerra de Independencia. En ese marco, el fusilamiento de los 38 prisioneros
ordenado por Santander en octubre de 1819, se analiza como un hecho que provocó
discusiones sobre filantropía y civilización y como hecho que motivó la firma de
al Tratado de Trujillo entre Bolívar y Morillo en 1820. Dicho tratado se entiende
como un reconocimiento de facto de la República de Colombia, un mecanismo para
promocionarla en el mundo civilizado, y una primera sistematización del derecho
de gentes en el mundo americano.
Oriente son los otros: Occidente, protestantismo e islam en el pensamiento de Ziya Gökalp
Authors: Gil Guerrero Javier
Published: February 2025

Espoleado el acoso de las potencias europeas y el fracaso de la liberalización
emprendida por los Jóvenes Otomanos, Ziya Gökalp desarrolló un programa que
buscaba reconciliar las visiones asimilista y refractaria con respecto al proyecto
de occidentalización y modernización. Su pensamiento fue tomado tanto por los
Jóvenes Turcos como por Atatürk y es fundamental para entender la Turquía del
siglo XX. Separando los conceptos de cultura y religión de la idea de civilización,
Gökalp propuso una interpretación esencialista de los primeros y sincretista de
la última. Para justificar una entrada de los turcos en la civilización occidental
moderna sin renunciar a su cultura y religión, Gökalp presentó un relato que situaba
al islam en el origen de la modernidad occidental surgida a partir de la Reforma. Al
establecer un parentesco entre islam y protestantismo, Gökalp también pretendía
disociar a los turcos de cualquier vínculo con la idea de Oriente
Design Battery Charger With CC-CV Method for Series Connected Lithium-Ion Batteries Using Fuzzy Logic Controller
Authors: Sutedjo Sutedjo , Rakhmawati Renny , Putih Bening Putri Permata , Adila Ahmad Firyal , Irianto Irianto , Yanaratri Diah Septi
Published: February 2025

Considering the many human needs, the existence of solar energy is considered very appropriate to help meet the energy needs consumed by humans. All the energy produced by solar panels can be stored using batteries which can then be converted into electrical energy. The battery will work when the energy stored in the battery is fulfilled, but if the use of the battery is carried out continuously it causes the energy in the battery to run out, so that the battery energy must be recharged immediately so that it can still be used again. charging which is used to recharge battery energy at this time unfortunately it still takes quite a long time to be recharged. Through the description of the problem, so that in study this is a tool fast charging use buck converter by using the method (Constant Current) CC-CV (Constant Voltage) on a Lithium-Ion battery. Buck converter This is necessary because the source used in this study is a solar panel which produces a very high voltage, so the voltage needs to be lowered by using buck converter. Using a 11.1V / 2.2 Ah LithiumIon battery. To keep the current and voltage constant, the charging process is carried out charging this current and voltage the output will be stabilized by Fuzzy Logic Controller (FLC). From the simulation results that have been carried out, it appears that the FLC has been able to stabilize the charging current of 2.2Ah and 11.1V.
Analysis the Impact of Inset Fed Design with Reference Impedance of Rectangular Microstrip Patch Antenna using Neural Network
Authors: Fariza Nadilla
Published: February 2025

Abstract -- Research on microstrip antennas is currently growing in prevalence, as their compact design and low cost make them simple to adapt to various needs. The goal of this study is to find out how the inset-fed depth affects the impedance matching of a rectangular microstrip antenna using a simple RMSA design. The author designs the antenna to operate at a frequency of 2.4 GHz with an FR-4 epoxy substrate and simulates it using CST Suite Studio 2019 software. The research shows that adding an inset fed with a depth of 5 mm results in an impedance value of 50.28 + j3.68 Ω, which is close to the desired impedance. The computation process using Neural Network reduces simulation time by 65% faster compared to CST simulation.
Machine learning in shoulder arthroplasty
Authors: Schneller Tim , Kraus Moritz , Schätz Jan , Moroder Philipp , Scheibel Markus , Lazaridou Asimina
Published: February 2025

Aims

Machine learning (ML) holds significant promise in optimizing various aspects of total shoulder arthroplasty (TSA), potentially improving patient outcomes and enhancing surgical decision-making. The aim of this systematic review was to identify ML algorithms and evaluate their effectiveness, including those for predicting clinical outcomes and those used in image analysis.

Methods

We searched the PubMed, EMBASE, and Cochrane Central Register of Controlled Trials databases for studies applying ML algorithms in TSA. The analysis focused on dataset characteristics, relevant subspecialties, specific ML algorithms used, and their performance outcomes.

Results

Following the final screening process, 25 articles satisfied the eligibility criteria for our review. Of these, 60% focused on tabular data while the remaining 40% analyzed image data. Among them, 16 studies were dedicated to developing new models and nine used transfer learning to leverage existing pretrained models. Additionally, three of these models underwent external validation to confirm their reliability and effectiveness.

Conclusion

ML algorithms used in TSA demonstrated fair to good performance, as evidenced by the reported metrics. Integrating these models into daily clinical practice could revolutionize TSA, enhancing both surgical precision and patient outcome predictions. Despite their potential, the lack of transparency and generalizability in many current models poses a significant challenge, limiting their clinical utility. Future research should prioritize addressing these limitations to truly propel the field forward and maximize the benefits of ML in enhancing patient care.

Cite this article: Bone Jt Open 2025;6(2):126–134.
Food for the Lewd: Ananius fr. 5 & 6W
Authors: Hawkins Shane
Published: February 2025

Abstract: Ananius fr. 5 is not simply a list of gastronomic delights but an extended series of humorous metaphors of a type common among early iambic and comic authors. The bon vivant image of the poem, whether merely ironic or echoing ethical concerns with consumption and self-control, and the confusion surrounding Ananius’ name and identity are all difficult points of interpretation. It is argued here that, although he is often thought of as representing a gentler strand of the iambic repertoire, a comparison with the Homeric Odysseus suggests that Ananius is a more familiar iambic figure than previously thought.
Lucian’s Queer Book User in the Adversus Indoctum
Authors: Lambert Cat
Published: February 2025

Abstract: Lucian’s Adversus Indoctum has long held the interest of book historians, but one curious feature of the text—a feature that seemingly has little to do with books—remains undertheorized. Two thirds of the way through the satire, the speaker outs the so-called “ignorant book collector” as a kinaidos . Jointly engaging book history and queer studies, this article argues that treating the kinaidos as a core feature of the satire unlocks a new perspective onto the book collector. Rather than being hapless and vain, the kinaidic book collector embodies a queer relation to books as objects that undercuts the authority of his attacker. This “bibliographically queer” mode of reading illuminates how Lucian challenges and playfully subverts the dominant perspectives of his time.
Servius’ Use of Persius in His Commentary on Vergil’s Aeneid : Uncovering a Rich Intertextual Dialogue
Authors: Celotto Giulio
Published: February 2025

Abstract: This paper shows that in his commentary on Vergil’s Aeneid Servius makes significant use of Persius’ Satires . Although these poems are mainly cited in the context of linguistic explanations, the selection of the material reveals Servius’ close familiarity with Persius’ work, as well as his thorough understanding of the satirist’s allusive engagement with Vergil. Most of the parallels are drawn from scenes where Persius evokes Vergil either directly to comment on his predecessor’s poetic technique, or indirectly to create a comic effect by describing the morally degraded world of his satires with the language of a loftier literary genre.
Using ENGAGED for CHANGE to Develop a Multicultural Intervention to Reduce Disparities among Sexual and Gender Minorities in Appalachia
Authors: Rhodes Scott D. , Tanner Amanda E. , Alonzo Jorge , Mann-Jackson Lilli , Chaffin John W. , Garcia Manuel , Erb Hannah J. , Sucaldito Ana D. , Williams Faller Rachel E. , Stafford Jeanette M. , Russell Laurie , Weil Peggy H. , Jibriel Mohammed Sheikh Eldin , McGuire Tucker , Wilkin Aimee M. , Aguilar-Palma Sandy K. , Kline David M.
Published: February 2025

Abstract: Background: Gay, bisexual, queer, and other men who have sex with men (GBQMSM) and transgender persons in Appalachia are at an increased risk for HIV, sexually transmitted infections (STIs), hepatitis C virus (HCV), mpox (formerly known as monkeypox) and are less likely to use prevention and care services. Objectives: Our community-based participatory research partnership sought to develop an intervention to increase use of HIV, STI, HCV, and mpox prevention and care services among diverse GBQMSM and transgender and nonbinary persons living in rural Appalachia. Methods: We used ENGAGED for CHANGE , a novel community-engaged participatory intervention development process, to integrate two evidence-based strategies—community-based peer navigation and mHealth—into a multi-cultural intervention. Results: The developed Appalachian Access Project intervention contains five modules to train GBQMSM and transgender and nonbinary persons to serve as peer navigators (known as “community health leaders”) within their social networks. The modules are designed to increase awareness of HIV, STIs, HCV, and mpox and their prevention and care; provide guidance on how to promote use of services, including pre-exposure prophylaxis, syringe services, and medically supervised gender-affirming hormone therapy; improve understanding of social determinants of health; and increase ability to effectively communicate and apply social support strategies in person and through mHealth social media. Conclusions: The Appalachian Access Project intervention builds on the strong, preexisting social networks of GBQMSM and transgender and nonbinary persons. It is designed to meet the needs and priorities of underserved and minoritized communities in rural Appalachia through community-based peer navigation and mHealth.