bluuebunny/crossref_metadata_2025 huggingface dataset:
The Analysis of relation to brain iron deposition of Parkinson’s Disease using Quantitative Susceptibility Mapping
Authors: Jeon Gyu-Ri , Lee Han-Gyul , Kwon Seung-won , Cho Seung-Yeon , Jung Woo-Sang , Moon Sang-Kwan , Park Jung-Mi , Ko Chang-Nam , Park Seong-Uk
Published: March 2024

Objectives: This study aimed to investigate the levels of brain iron deposition in Parkinson's disease (PD) patients using Quantitative Susceptibility Mapping (QSM) and to determine whether distinctions compared to the general population exist. Furthermore, we examined potential variations in iron deposition among different PD subtypes.Methods: Structural brain imaging was conducted on 75 participants at Gangdong Kyung Hee University Hospital between August 2017 and May 2020. PD patients were categorized into Tremor Dominant (TD) and Postural Instability and Gait Difficulty (PIGD) subtypes. Voxel-based morphometry and QSM were employed to compare voxel-wise magnetic susceptibility across the entire brain between Normal Controls (NC) and PD groups. Subsequently, QSM values were compared between TD and PIGD groups.Results: QSM values were compared among 46 PD patients and 23 normal controls, as well as between TD (n=22) and PIGD (n=24) groups. Voxel-based QSM analysis revealed no significant differences between groups. Similarly, ROI-based QSM analysis showed no significant distinctions.Conclusions: No significant variations were observed between the PD patient group, NC group, or PD subtypes. This study systematically compared QSM values across a broad range of brain regions potentially linked to PD pathology. Additionally, the subdivision of the PD group into TD and PIGD subtypes for QSM-based iron deposition analysis represents a meaningful and innovative approach.
Current Status of Informed Consent Form for Acupotomy in Korean Medicine Hospitals and Development of a Standard Informed Consent Form Using Delphi Method
Authors: Kim Jihun , Goo Bonhyuk , Kim Hyongjun , Seo Kyoungsuk , Oh Myungjin , Ryu Myungseok , Yoon Sang-Hoon , Lee Kwang Ho , Lee Hyun-Jong , Leem Jungtae , Jun Hyungsun , Jeong Ihn Sook , Choi Sung Woon , Lee Tae Wook , Kim Yeonhak , Oh Yoona , Kim Kunhyung , Yang Gi Young , Kim Eunseok
Published: March 2024

Objectives: This study was conducted to develop a standard acupotomy consent form that takes into account the unique characteristics of Korean Medicine. The study was motivated by the increasing importance of patient autonomy and the growing number of legal disputes related to medical malpractice in the clinical field of Korean Medicine.Methods: The analysis phase of the study involved a survey of the current status of acupotomy consent forms in Korean Medicine hospitals nationwide. The items of each form were analyzed based on the contents of the Medical law and the standard contract for medical procedures of the Fair Trade Commission (FTC). In the development and evaluation phase, the items and contents of the acupotomy consent form were evaluated using a 5-point Likert scale and content validity was assessed through two rounds of Delphi surveys. In the improvement phase, the contents of the consent form were revised based on the results of a survey of inpatient and outpatient patients in the Department of Acupuncture and Moxibustion at Pusan National University Korean Medicine Hospital, and real-time online meeting. The final version of the standard acupotomy consent form was completed after undergoing proofreading and corrections by a linguistics expert.Results: Only 30% of Korean Medicine hospitals have implemented acupotomy consent forms. The items of the consent forms did not fully include the items presented in the Medical act and the standard contract for medical procedures of the FTC. To address this issue, two rounds of Delphi surveys and a real-time discussion were conducted with a panel of 12 experts on 27 preliminary items of consent forms. The items and contents that met the criteria for content validity ratio, convergence, and consensus were derived. Based on the derived items and content, a standard acupotomy consent form was developed.Conclusions: The standard consent form for acupotomy is anticipated to ensure patient autonomy and enhance transparency and liability in acupotomy. Furthermore, it is expected to serve as evidence in case of medical disputes related to acupotomy and contribute as a reference document for the development of standard consents forms for various procedures of Korean Medicine. However, the limitations of the study include that the survey of consent forms was limited to only training hospitals of Korean Medicine, and the standard consent form is only applicable to adults in Korea. Future studies are needed to address these limitations.
Pilot Development of a 'Clinical Performance Examination (CPX) Practicing Chatbot' Utilizing Prompt Engineering
Authors: Kim Jundong , Lee Hye-Yoon , Kim Ji-Hwan , Kim Chang-Eop
Published: March 2024

Objectives: In the context of competency-based education emphasized in Korean Medicine, this study aimed to develop a pilot version of a CPX (Clinical Performance Examination) Practicing Chatbot utilizing large language models with prompt engineering.Methods: A standardized patient scenario was acquired from the National Institute of Korean Medicine and transformed into text format. Prompt engineering was then conducted using role prompting and few-shot prompting techniques. The GPT-4 API was employed, and a web application was created using the gradio package. An internal evaluation criterion was established for the quantitative assessment of the chatbot's performance.Results: The chatbot was implemented and evaluated based on the internal evaluation criterion. It demonstrated relatively high correctness and compliance. However, there is a need for improvement in confidentiality and naturalness.Conclusions: This study successfully piloted the CPX Practicing Chatbot, revealing the potential for developing educational models using AI technology in the field of Korean Medicine. Additionally, it identified limitations and provided insights for future developmental directions.
A Case of Chronic Nummular Dermatitis Improved by Hwangryunagyo-tang
Authors: Lee Ju-Hyun , Lee Sang-Bae , Jo Eun-Heui , Park Min-Cheol
Published: March 2024

Objectives: This study aims to report a case of chronic nummular dermatitis improved by Hwangryunagyo-tang.Methods: The patient in this study was a 15-year-old female, who visited our hospital with symptoms such as redness, erythema, papule, excoriation, scale, exudation, crusting, lichenification, and pruritus of the extremities and trunk. Considering that the skin lesions were coin-shaped and persisted for more than 6 months, the patient's symptoms were diagnosed as chronic nummular eczema. Based on the patient's symptoms and overall condition, Hwangryunagyo-tang was prescribed.Results: Approximately 4 months after administration of Hwangryunagyo-tang, the exudate disappeared, and overall skin symptoms improved, from objective score 33.7 to 6.6, leaving only slight scale, dryness, and pigmentation. As the pruritus of the skin lesion decreased from numeric rating scale 8 to 1, the patient's sleeping condition also improved from numeric rating scale 9 to 0.Conclusion: This study is significant in that the symptoms of chronic nummular dermatitis were effectively improved after administration of Hwangryunagyo-tang.
Chuna therapy include Space Spinal Conduction Exercise and Manipulation Treatment for Functional dyspepsia patients: A case report
Authors: Yu Myung-hwan , Cho Jae-Heung
Published: March 2024

Objectives: The purpose of this case study was to report the effect of Chuna therapy include Space Spinal Conduction Exercise and Manipulation Treatment for Functional dyspepsia patients.Methods: A 32-years-old male patients with functional dyspepsia visited the clinic ten times from March 17th 2023 to April 22th 2023. To assess the treatment outcomes, we used the Standard tool for pattern identification of Functional dyspepsia and Nepean Dyspepsia Index-Korean version (NDI-K) symptom score.Result: After treatment, Standard tool for pattern identification of Functional dyspepsia and Nepean Dyspepsia Index-Korean version (NDI-K) score decreased.Conclusion: Chuna therapy include Space Spinal Conduction Exercise and Manipulation Treatment was effective in the treatment of patient with Functional dyspepsia.
A Case of Presbystasis Patient Improved after Korean Medicine Treatment - Focusing on Taking Gamiboik-tang and Body Balance Test
Authors: Park JungGun , Lee Hyo Gyung , Nam Hae Jeong
Published: March 2024

Objectives: We would like to report improvement in symptoms after performing Korean Medicine treatment including Gamiboik-tang administration to patient with presbystasis that lasts for more than a decade.Methods: An 83-year-old male patient diagnosed with presbystasis was administered Gamiboik-tang for 4 weeks and acupuncture was performed. The degree of improvement is evaluated based on the body balance test and the patient's subjective symptom change.Results: Both the body balance test and the patient’s subjective symptoms improved after administration of Gamiboik-tang and Korean Medicine treatment Conclusions: Korean Medicine treatment, including Gamiboik-tang administration and acupuncture treatment, is thought to be effective for presbystasis.
Korean Medicine Treatment Accompaning Myofascial Trigger-Point Accupuncture for Lower Urinary Tract Symptoms after Radical Prostatectomy : A Case Report
Authors: Lee Jin Kwang
Published: March 2024

Objectives: The purpose of this study is to report a case of Korean medicine treatment accompaning myofascial trigger-point accupuncture for severe & persistent lower urinary tract symptoms after radical prostatectomy.Materials and Methods: A prostate cancer patient with severe & persistent lower urinary tract symptoms after radical prostatectomy conducted 26 months ago, was treated with Korean medicine accompaning myofascial trigger-point accupuncture. The International Prostate Symptom Score(IPSS), the IPSS Quality of Life(IPSS-QoL) and the Overactive Bladder Symptom Score(OABSS) questionaires were administered to evaluate the effect of treatment for lower urinary tract symptoms.Results: After 5 month treatment with Korean medicine accompaning myofascial trigger-point accupuncture, IPSS, IPSS-QoL and OABSS progressed from 28 to 8, from 5 to 2 and from 12 to 4 respectively.Conclusion: This case study suggests that Korean medicine accompaning myofascial trigger-point accupuncture may contribute to treat severe & persistent lower urinary tract symptoms after radical prostatectomy.
The short-term effect of Blood Pressure Reduction after Biofeedback in Malignant Hypertension: A case report
Authors: Oh Seung-Yun , Kim Yeon-Ju , Kim Lak-Hyung , Park Soo-Jung
Published: March 2024

Objectives: The purpose of this study was to report the short-term blood pressure-lowering effects observed in a patient with malignant hypertension through slow breathing maneuver with heart rate variability(HRV) biofeedback.Methods: Biofeedback sessions, totaling 13, each lasting 10 minutes, were administered. Blood pressure was measured pre and post-treatment, as well as thrice daily at 10 am, 4 pm, and 8 pm. Systolic blood pressure(SBP), diastolic blood pressure(DBP), and pulse rate were recorded for comparative analysis.Results: Before biofeedback, the average SBP, DBP, and pulse rate were 227.2±18.3, 135.2±11.0, and 104.4±5.3, respectively. Immediately post-biofeedback, these values changed to 213.7±15.2, 126.9±8.5, and 99.2±3.6. However, sustained long-term blood pressure reduction was not observed.Conclusions: The findings suggest that biofeedback therapy induces a short-term reduction in blood pressure in cases of malignant hypertension, potentially associated with autonomic nervous system regulation. Integrating biofeedback with other Korean medicine treatments, such as acupuncture or moxibustion, may offer a comprehensive approach for managing malignant hypertension.
Current Status and Sustainable Development Strategies of Traditional Korean Medicine Official Development Assistance (ODA) in Global Health
Authors: Hwang Yeeun , Lee Seunghyeon , Kim Hyungwoo , Nam Hyoju , Lee Seungun , Baik Yousang , Chae Han
Published: March 2024

Objectives: Korea has a unique history of being both a recipient and a donor of Official Development Assistance (ODA), and the international community expects Korea to contribute to the development of developing countries by utilizing this experience. Traditional Korean medicine (TKM) seeks to contribute to global health, however the concept of ODA has been unclear and there has been no clear strategy and sustainable initiatives.Methods: This study examines the concept of ODA and its application in global health, including business objectives, scale, evaluation principles, and development strategies. Additionally, we reviewed the current status of Traditional Korean medicine globalization projects and conducted a SWOT analysis of the internal and external environment of the TKM sector. Based on these findings, we redefined the concept of ODA for TKM and proposed suggestions for its development.Results: The current study identified key ideas for TKM ODA. It should prioritize the improvement of primary healthcare in recipient countries, aligning with the international evaluation criteria of the SDGs. Secondly, TKM's 70 years of experience can be leveraged to enhance both the competence and economic benefits of recipient countries' medical systems. Based on these concepts, a TKM ODA development model was proposed, comprising two core visions, three development strategies and goals, and six core values.Conclusion: This study systematically examined the TKM in global health and suggested sustainable development strategies for TKM ODA. Through its expansion, TKM could contribute to the advancement of global traditional medicine and its overall engagement in healthcare.
The Becomings of a Mime: Dis/empowerment in Borges' "Emma Zunz"
Authors: Estrada Jorge
Published: March 2024

Abstract: In the short story "Emma Zunz," Borges depicts a character seeking revenge and justice, but to enact her clear, straightforward intentions, the eponymous protagonist must engage in a mirror game, a game of mimicry in which Emma Zunz reproduces diverse sources, creates an overlap, and in this manner undergoes a process of dis/empowerment. Her actions become overdetermined and acquire a multifaceted meaning, but lose its single, identifiable, and original intention. The murder, which as a single action should have completed her revenge, becomes part of a continuous unfolding of versions and subversions of the same event and, in this manner, reveals a narrative structure challenging the idea of an autonomous and self-contained rational subject. To shed light on the dis/empowerment ensuing when a character is described in terms of a potential to affect and be affected, my approach builds up on mimetic studies as well as on Deleuze's and Lacoue-Labarthe's reflections.
The expression of the surfactant proteins SP-A and SP-B during postnatal alveolarization of the rat lung
Authors: Roeder Franziska , Knudsen Lars , Schmiedl Andreas
Published: March 2024

Objective

Surfactant-specific proteins (SP) are responsible for the functional and structural integrity as well as for the stabilization of the intra-alveolar surfactant. Morphological lung maturation starts in rat lungs after birth. The aim of this study was to investigate whether the expression of the hydrophilic SP-A and the hydrophobic SP-B is associated with characteristic postnatal changes characterizing morphological lung maturation.

Methods

Stereological methods were performed on the light microscope. Using immunohistochemical and molecular biological methods (Western Blot, RT-qPCR), the SP-A and SP-B of adult rat lungs and of those with different postnatal developmental stages (3, 7, 14 and 21 days after birth) were characterized.

Results

As signs of alveolarization the total septal surface and volume increased and the septal thickness decreased. The significantly highest relative surface fraction of SP-A labeled alveolar epithelial cells type II (AEII) was found together with the highest relative SP-A gene expression before the alveolarization (3th postnatal day). With the downregulation of SP-A gene expression during and after alveolarization (between postnatal days 7 and 14), the surface fraction of the SP-A labeled AEII also decreased, so they are lowest in adult animals. The surface fraction of SP-B labeled AEII and the SP-B gene expression showed the significantly highest levels in adults, the protein expression increased also significantly at the end of morphological lung maturation. There were no alterations in the SP-B expression before and during alveolarization until postnatal day 14. The protein expression as well as the gene expression of SP-A and SP-B correlated very well with the total surface of alveolar septa independent of the postnatal age.

Conclusion

The expression of SP-A and SP-B is differentially associated with morphological lung maturation and correlates with increased septation of alveoli as indirect clue for alveolarization.
Becoming topological of heavy metal: Notes from India
Authors: Sarkar Debarun
Published: March 2024

The article argues for doing away with master concepts such as ‘subculture’ and similar ancillary concepts and instead argues for the open-ended pursuit of the social. Instead of deploying a priori spatiotemporal concepts such as ‘subculture’, ‘scene’ or ‘tribe’ it argues that a more fruitful approach would be to interrogate the work that these concepts do. It is important to grasp how and if these concepts close down or open up the field. The article argues that these concepts are necessarily topological and scalar, i.e. they are concerned with fixing musical collectivities in space–time. Through two ethnographic vignettes from India – of metal gigs in Kolkata and Bengaluru set a decade apart – the article argues for a minor and open-ended approach to heavy metal. Against the master concepts, the article argues for a seepage of minor aesthetics into our theorizations which can challenge the totalizing impulse of theory. An open-ended pursuit of heavy metal allows comprehension of a range of human and non-human processes in the social which otherwise risk being obfuscated by a narrow concern of chasing a master concept. In the concluding section, the article ends with a brief methodological note on the black metal/punk/grindcore act from India, Heathen Beast and the difficulty of situating them through conventional concepts.
Kvetching abovt kvlt: Conflicting social uses of the index ‘kvlt’ in online metal spaces
Authors: Robertson Wesley C.
Published: March 2024

The word ‘kvlt’, generally pronounced as ‘cult’, is a well-recognized linguistic feature of (black) metal discourse. To date, over a dozen academic studies have included reference to the term, and all are united in sharing a broad consensus that ‘kvlt’ serves as a marker of ‘black-metal-ness’ or black metal aesthetics. The common recognition of ‘kvlt’ in both metal scenes and academic studies belies a lack of actual investigation of how the word is used, however, with ‘kvlt’ extensively appearing in discussions of metal but seeing little analysis itself. Approaching ‘kvlt’ as an index, i.e. a linguistic form linked to contested social meaning(s), the current study attempts to better understand ‘kvlt’ itself through analysis of how ‘kvlt’ is used across contemporary metal discourses. The study’s data comes from 200 uses of ‘kvlt’ divided between two sources: the Metal Archive Forums and the Reddit forum (or ‘subreddit’) r/blackmetal. Through analysing these uses in context, the study finds that while many previously attested uses of ‘kvlt’ certainly exist, there are differences in how ‘kvlt’ is used and differences in the extent to which they actually signal internal borders within (black) metal communities. Not only do black metal focused spaces utilize ‘kvlt’ differently from more generic metal ones, but also the ways that ‘kvlt’ is used to praise, critique or even simply describe metal music and scenes differ as well. As a result, the study argues that both discourse around ‘kvlt’ and the use of ‘kvlt’ itself are more than just a form of subcultural capital, serving also as part of contemporary metal identity work, boundary policing and debates over the proper ways to ‘be’ or ‘do’ metal.
A professzionalizáció szerepe a hazai közepes méretű családi vállalatok versenyképességében
Authors: Kárpáti Zoltán , Ferincz Adrienn
Published: March 2024

Jelen tanulmány célja a professzionalizáció szerepének vizsgálata a hazai közepes méretű családi és nem-családi vállalatok versenyképességében. Számos hazai tanulmány foglalkozott már a kis- és közepes méretű vállalkozások versenyképességével, ám kevés tett közülük különbséget családi és nem-családi között. A szerzők kutatása a családi vállalatok professzionalizációjára és az erőforrás-alapú elméletre épít, feltárva a családi és nem-családi cégek különböző erőforrás- és képességkombinációit, valamint eltérő típusú stratégiájukat a versenyképességüket tekintve. A Budapesti Corvinus Egyetem Versenyképesség Kutatóközpont adatbázisán azonosították a családi vállalatok professzionalizációjával kapcsolatos változókat, amelyeken főkomponens majd klaszterelemzést végeztek. A kapott eredményeket összevetették a Vállalati Versenyképességi Index-szel. Az eredmények azt mutatják, hogy a családi cégek a kapcsolatépítésre, tudásmenedzsment és innovációs képességeikre, míg a nem-családi versenytársaik a működési kiválóságra és vezetői képességeikre koncentrálnak. Jelen mintában a nem-családi cégek értek el magasabb professzionalizációs szintet és versenyképességi értéket, ám ez nem jelenti azt, hogy a családi tulajdonban lévők ne lehetnének versenyképesek.
A kulturális diverzitás megjelenése nemzetközi projektcsapatokban – A virtuális és személyes részvételű csapatmunka összehasonlító elemzése
Authors: Yousef Katul
Published: March 2024

Jelen tanulmány a kulturális sokszínűség megjelenési formáit vizsgálja a virtuális és személyes részvételű csapatmunka során. A nemzetközi üzleti és menedzsmentképzésben kiemelkedően fontos a kulturális sajátosságok eltérő megnyilvánulásának megértése, értelmezése és az ezekhez igazodó interkulturális kompetenciák fejlesztése. Annak érdekében, hogy megértsük a kulturális diverzitás kihívásait a csapatmunka során, a kutatáshoz egy hallgatói projektmunkát hirdettek meg, amelyben 65 egyetemi hallgató vett részt. A résztvevők két alkalommal adtak visszajelzést, így összesen 130 visszajelzés tartalmát elemezték az NVivo szoftver segítségével. A kutatási eredmények rávilágítottak arra, hogy a virtuális csapatmunka alatt a kulturális sokszínűséget gyakran kockázati tényezőnek tekintik a projekttagok, ezzel szemben a projekt személyes része során a kulturális sokszínűség értékes eszközként jelent meg, amely hozzájárult az innovatív és kreatív megoldásokhoz. A kutatás kritikus szemléletmódot képvisel, hasznos lehet oktatók, vállalati szakemberek, projektmenedzserek számára, továbbá az üzleti és akadémiai szféra azon résztvevőinek, akik a kultúrák közötti interakciók optimalizálására törekednek a virtuális és személyes csoportmunkában egyaránt.
Reverse engineering of pump as turbine for CFD analysis
Authors: Souček Jiří , Bílková Eva , Nowak Petr
Published: March 2024

Reverse engineering (RE) using 3D scanning is already a relatively technologically simple and cost-effective method. For water turbines, this is particularly true for RE of larger machines. With microturbines, there is a lot of pressure to minimise costs, even at the cost of reduced accuracy. Using an existing micro-PAT (Pump as Turbine) as an example, we showed the approach to assessing these microturbines, starting with scanning the entire internal flow profile of the turbine, reconstructing the surface into a 3D model, and numerically assessing it using CFD (Computational Fluid Dynamics). A different approach is necessary compared to standard large machines, whose dimensions allow troublefree scanning of the flow parts of the turbine. Using CFD, we assessed the reconstructed geometry of the PAT. Two significant findings were made: the importance of high-quality 3D scanning by combining several cheaper 3D scanners and the necessity for reliable in-situ measurements for a successful CFD validation. Our future focus involves optimising PAT runner geometry in turbine mode to enhance energy production at the site and, at the same time, eliminating existing cavitation.
Analysis of Differences in the Use of Kahoot and Quizizz Applications in Improving Analytical Thinking of Physics Education Students, Universitas Negeri Yogyakarta
Authors: Amalia Ayu , Daynuari Mellina Ayu , Setiaji Bayu
Published: March 2024

Learning media is one of the important things in determining the results of the learning process. Interesting learning activities by focusing the interaction between lecturers and students will increase motivation in learning. Therefore, it needs to be packaged well, one of which is an interactive quiz after learning. There are several online quizzes that are often used, namely Kahoot and Quiziz, these quizzes provide services for users to create their own quizzes and can share them with others to take quizzes. The purpose of this study was to determine whether there was a difference in the use of the Kahoot and Quizizz quizzes in improving the analytical thinking of students of Physics Education C UNY 2020 on light interference material. The research method used is an experimental research method in quasi experiment with posttest only design where the research subject will do an analytical ability test given in the form of multiple choice questions given through Kahoot and Quizizz. After that, data analysis will be carried out using a t-test, the results of the analysis show that there are differences in the use of the two quizzes, namely Kahoot and Quizizz with a significance value of 0.642.
Development of TPACK-Based Physics Magazine as Teaching Material for High Schools: A Study on Rotational Dynamics and Rigid Body Equilibrium
Authors: Junaida  , Fitriyawany  , Ilyas Zahriah
Published: March 2024

This study aims to develop a physics teaching magazine based on Technological Pedagogical and Content Knowledge (TPACK) for senior high school students, focusing on rotational dynamics and equilibrium of rigid bodies. Employing a Research and Development (R&D) approach with the 4-D model, the process encompassed definition, design, and development stages. The magazine's content and media aspects were validated by experts, achieving feasibility scores of 94% and 87.9%, respectively. The magazine was evaluated by students of SMAN 1 Lembah Seulawah Aceh Besar, with results indicating strong acceptance and effectiveness as a learning medium. While the study confirms the potential of TPACK-based interactive learning materials in science education, its limited scope and sample size suggest caution in generalizing the findings. Future research should expand the scope, involve larger samples, and integrate diverse technological tools. This research contributes to the discourse on digital competencies in science education, emphasizing the need for innovative materials and continuous professional development.
The Development of Electronic-based Student Worksheets to Facilitate the Critical Thinking Skills of Tenth Graders
Authors: Yanti Alya Rahma , Mawardi Ari Cahya
Published: March 2024

Smartphones become something familiar to learners. Most learners have smartphones. Learners require guidance to use smartphones for learning. This matter becomes the principle of developing an electronic-based worksheet. Based on the encountered problems especially the materials about renewable energy and critical thinking, the learners needed the development of an electronic-based worksheet to facilitate their cognitive skills within the material of renewable energy.  This research and development, R&D, applied the 4D design, starting from defining, designing, developing, and disseminating. However, this research only lasted until the development stage specifically the limited test. The result showed the category of extremely excellent from the learners. On the other hand, the implementation of the whole aspect was done excellently.
Computational Analysis of Free Fall Motion with Air Friction Constraints
Authors: Miyaqi Iqlides Ahmad , Supardi  , Barokah Najilul
Published: March 2024

Free fall motion without initial velocity is a mechanical concept that can be analyzed using analytical, experimental, and computational methods. Free fall motion is difficult to analyze analytically if air friction is not neglected. The aim of this research is to explain computational free fall motion analysis procedures with air friction. Air friction disturbance in free fall motion is represented by the coefficient C which states the drag coefficient is time dependent. In this scientific study, the application used for computational analysis is IDE Spyder with various library support. With the help of this application, a significant difference in the output vmax and tmax is obtained between the two cases of free fall based on the interpretation of the graph that appears.
Konsep Pemimpin Ideal dalam Pemikiran Al-Farabi dan Al-Mawardi
Authors: Pangesti Hestyana Widya , Muthiullah  , Rahmat Hidayat
Published: March 2024

Problematika tentang pemimpin ideal sudah ada sejak dahulu yang berlangsung dari zaman ke zaman. Berbagai kriteria dimunculkan untuk mewujudkan pemimpin yang ideal dalam suatu negara. Al-Farabi dan Al-Mawardi adalah dua konseptor yang telah merusmuskan konsep pemimpin ideal. Keduanya memiliki kesamaan dan perbedaan dalam mencantumkan kriteria pemimpin Ideal, meskipun keduanya hidup di bawah Dinasti yang sama. Penelitian ini adalah kualitif dengan pendekatan studi pustaka (Library Research). Data dikumpulkan dengan membaca buku primer Al-Madinah Al-Fadilah milik Al-Farabi dan Al-ahkam Al-Sulthaniyyah karya Al-Mawardi. Fokus penelitian adalah mengkaji konsep kepemimpinan Al-Farabi dan Al-Mawardi. Hasil penelitian menunjukkan adanya kesamaan pemikiran Al-Farabi dan Al-Mawardi dalam mencatumkan kriteria pemimpin yaitu memilik tubuh dan pancaindera yang sehat dan lengkap, akal dan ilmu pengetahuan, akhlak dan budi pekerti, keberanian dalam membela negara. Perbedaannya ada pada kerincian syarat Al-Farabi yaitu tuturan yang baik dan jujur dan menjauhi kenikamatan dunia sedangkan Al-Mawardi yaitu bersuku Quraisy dan memiliki keseimbangan seluruh kriteria. Hasil lainnya Al-Farabi cenderung menyeimbangan hubungan vertikal dan horizontal pada konsep pemimpin idealnhya sedangkan Al-Mawardi lebih mengutamkan hubungan vertikal dari pada hubungan horizontal dalam prinsip pemimpin idealnya.
Kata Kunci: Pemimpin Ideal, Al-Farabi, Al-Mawardi
Reconception of Environmental Ethics in Islam: A Review of the Philosophy and Applications of Husein Nasr's Thought
Authors: Syihabuddin Muhammad , Kirwan
Published: March 2024

Wacana mengenai krisis dan etika lingkungan sangat penting untuk dikaji lebih mendalam. Hal ini karena kajian tersebut tidak pernah berhenti hanya sekedar konsep belaka dan selalu diperdebatkan. Tujuan tulisan ini ingin memahami gagasan Husein Nasr mengenai konsep etika lingkungan dalam bingkai ajaran tasawuf Islam (ekosufisme), aplikasi penerapan pemikiran Nasr, hingga gagasan filsafat etika lingkungan yang inklusif dan berkelanjutan. Metode yang digunakan dalam tulisan ini adalah pendekatan literatur berbasis deskriptif kualitatif berlandaskan teori atas pemikiran Husein Nasr mengenai Manusia, Tuhan, dan Alam. Adapun pengumpulan data dengan cara mengumpulkan beberapa teks-teks yang sesuai dengan topik yang dibahas berupa artikel dan buku dan dianalisis dengan teknik analisis keyword, abstrak, dan hasil atau kesimpulan pada sumber yang serupa. Hasil yang ditemukan 3 hal: Pertama, Husein Nasr menawarkan ajaran hubungan antara manusia dengan alam hablun min alam berupa ekosufime sebagai penghantar hubungan harmoni antara Tuhan, manusia, dan alam. Kedua, secara aplikatif, berupa integrasi antara rekonsepsi dan kesadaran manusia sebagai khalifah fil ardhi untuk menjaga bumi. Terakhir yaitu merekonsepsikan filsafat etika lingkungan yang bersifat inklusif dan berkelanjutan dengan melibatkan para stakeholder berpartisipasi untuk kedaulatan alam.
Kata Kunci: Husein Nasr, Ekologi, Ekosufisme, Inklusif
BİYOSANATIN AHLAKİ FAİLLİĞİ SORUNU
Authors: USLU Ayşe
Published: March 2024

The meaning of creating aesthetic value has been defined as an activity as an end in itself in the sense of not serving any other interest or human need. In this respect, art seems free of social value judgements and practical concerns. In parallel, an artist’s conflict with social values is accepted as normal in the name of the freedom of artistic expression. The risk of moralism causes a separation between ethics and aesthetic values. The discussion surrounding "moralism" and "artistic autonomy" revolves around the argument for a clear separation between art and ethics, or their integration with one another. Whereas moralism reduces aesthetic value to ethical value, autonomism claims autonomy of aesthetic and ethical values because of the legacy of ethical criticisms. In this respect, this article dwells on the limits of art’s moral agency by placing it outside the extreme divide between moralism and autonomism. For this aim, the claim that every artwork cannot necessarily be subjected to ethical judgement or agency, because not all artworks consist of propositional knowledge, will be eliminated. Second, considering the fact that nonpropositional artwork is immanent to the social networks that they emerge from and their mutual effects on these networks, it will be asserted that artwork as a fabrication of reality can be seen as responsible for its actions. The relationship between art and ethics when the subject matter is "living beings" will be assessed through a bioethical lens by analyzing notable examples of bioart. Does art have a responsibility to treat living beings? The use of biotechnology by artistic aims and the forms of how bioengineered life becomes an artistic medium can be seen as either a break from traditional art and an artistic revolution or an intervention to “natural” processes and destroy the perception of the nature-human relationship. To emphasize the moral responsibility of new media art involving biotechnologies, it is recommended to concentrate on their connection to the broader social-material field and their impact, in addition to the physical characteristics of these artworks or the medium through which they are presented. By examining the impact of these artwork on biotechnological networks and societal relationships, it is possible to trace their ethical and political effects and differentiate the boundaries of their moral agency within the realm of bioart.
Nurses and Artificial Intelligence Implementation
Authors:   Jordan University of Science and Technology, M. Akhu-Zaheya, Laila
Published: March 2024

N.A
Marek Jakoubek – Vladimir Penčev: Češi a Slováci v Bulharsku. Příspěvky ke studiu české, slovenské a československé krajanské přítomnosti v bulharských zemích
Authors: Lančová Tereza
Published: March 2024

A review of the book by Marek Jakoubek and Vladimir Penčev.
Knockdown of ANP32E inhibits colorectal cancer cell growth and glycolysis by regulating the AKT/mTOR pathway
Authors: Liu Jiaojiao , Liu Yanchao , Zhao Qi
Published: March 2024

Colorectal cancer (CRC) is the third most common tumor, with an increasing number of deaths worldwide each year. Tremendous advances in the diagnosis and treatment of CRC have significantly improved the outcomes for CRC patients. Additionally, accumulating evidence has hinted the relationship between acidic nuclear phosphoprotein 32 family member E (ANP32E) and cancer progression. But the role of ANP32E in CRC remains unclear. In our study, through TCGA database, it was demonstrated that the expression of ANP32E was enhanced in COAD tissues (n = 286). In addition, the mRNA and protein expression of ANP32E was also confirmed to be upregulated in CRC cell lines. Further investigation uncovered that knockdown of ANP32E suppressed cell proliferation and glycolysis, and facilitated cell apoptosis in CRC. Moreover, inhibition of ANP32E inhibited the AKT/mTOR pathway. Through rescue assays, we discovered that the reduced cell proliferation, glycolysis and the enhanced cell apoptosis mediated by ANP32E repression was reversed by SC79 treatment. In summary, ANP32E aggravated the growth and glycolysis of CRC cells by stimulating the AKT/mTOR pathway. This finding suggested that the ANP32E has the potential to be explored as a novel biomarker for CRC treatment.
Photosynthetic physiological characteristics, growth performance, and element concentrations reveal the calcicole–calcifuge behaviors of three Camellia species
Authors: Chai Shengfeng , Jiang Haidu , Yang Yishan , Pan Xinfeng , Zou Rong , Tang Jianmin , Chen Zongyou , Zeng Danjuan , Wei Xiao
Published: March 2024

We grew three yellow Camellia species (the calcifuge C. nitidissima and C. tunghinensis, and the calcicole C. pubipetala) in acidic and calcareous soils for 7 months and assessed their photosynthetic physiological characteristics, growth performance, and element concentrations in this developmental context. The calcifuge C. nitidissima and C. tunghinensis species exhibited poor growth with leaf chlorosis, growth stagnation, and root disintegration in calcareous soils, and with their P
n, G
s, T
r, F
v/F
m, ΦPSII, ETR, qP, leaf Chla, Chlb, and Chl(a + b) concentrations, and root, stem, leaf, and total biomass being significantly lower when grown in calcareous soils relative to in acidic soils. In contrast, the calcicole C. pubipetala grew well in both acidic and calcareous soils, with few differences in the above parameters between these two soil substrates. The absorption and/or transportation of nutrient elements such as N, K, Ca, Mg, and Fe by the two calcifuge Camellia species plants grown in calcareous soils were restrained. Soil type plays a major role in the failure of the two calcifuge Camellia species to establish themselves in calcareous soils, whereas other factors such as competition and human activity are likely more important limiting factors in the reverse case. This study furthers our understanding of the factors influencing the distribution of these rare and endangered yellow Camellia species, allowing for improved management of these species in conservation projects and horticultural production.
Framing victimhood, making war: A linguistic historicizing of secessionist discourses
Authors: Isiaka Adeiza
Published: March 2024

As separatist yearnings resurge and gain traction in Nigeria, the agency of language and digitality in spreading dissident discourses has come under scrutiny. In this study, I investigate the linguistic-historical dimension of the Biafran movements, exploring the rhetorical frames by which the actors curate ethnic victimhood and sustain the secessionist struggle. Drawing on a corpus of memoiristic narrative of the Biafra war and digitally mediated discourses from a new Biafran movement – Indigenous People of Biafra (IPOB), I identify and discuss the central topoi of warspeak in both narratives across space and time. In this context, the notions of linguistic framing and atrocity propaganda are fruitfully integrated to analyse the range of rhetorical strategies for incentivizing the struggle and for animating its social capital. While both narratives draw on shared belongings, historical precedents, cultural frameworks, and atrocity stories for incitement, they vary in style and audience. I attribute the shifts to changes in actors’ demographics, discursive contexts, and Nigeria’s ethnopolitical cartographies.
Coping with old-age poverty – the role of agency and different forms of societal support
Authors: Grages Christopher , Och Ralf
Published: March 2024

Across Europe, there is a substantial but varying number of older people struggling to make ends meet. We examine how older people with a low income make use of their individual resources and those that are available from their family and community as well as public support (in cash and in kind) when coping with poverty. This article is based on the experience of old-age poverty, drawing on 59 life-course interviews with low-income older people in Norway, Germany, Estonia, Hungary, Italy, Spain and the United Kingdom. We introduce a typology of coping strategies with two main dimensions: the capacity for agency and the capacity for transformation. We show that coping strategies vary not only based on individual factors and appropriate social policy support, but also on further societal support provided by civil society, families or social networks that supplements or compensates for gaps in social policy provision.
Social policies and the life course – a complex relationship re-visited
Authors: Scherger Simone
Published: March 2024

Social policies structure individual life courses, cushion individual life course risks, and provide normative orientation. The paper brings together literature from life course sociology and welfare state research in order to provide an updated systematisation of the relationship between individual life courses and social policies. The modern life course regime and its welfare regulation are described as centred around individual actors, and as part and parcel of modernisation processes and the institutional arrangement mediating between the modern (democratic) state and the capitalist economy. Furthermore, the paper discusses these structural roots of life course policies, their resulting characteristics and their normativity. Key aspects in this are individualisation and its limits, the multilevel implementation of social policies and their life course effects with regard to inequalities.
Overview of Injectable Hydrogels for the Treatment of Myocardial Infarction
Authors: Yi Bingcheng , Xu Yiwei , Wang Xiaoyu , Wang Guangjun , Li Shuo , Xu Ruijie , Liu Xuequan , Zhou Qihui
Published: March 2024

Myocardial infarction (MI) triggers adverse remodeling mechanisms, thus leading to heart failure. Since the application of biomaterial-based scaffolds emerged as a viable approach for providing mechanical support and promoting cell growth, injectable hydrogels have garnered substantial attention in MI treatment because of their minimally invasive administration through injection and diminished risk of infection. To fully understand the interplay between injectable hydrogels and infarcted myocardium repair, this review provides an overview of recent advances in injectable hydrogel-mediated MI therapy, including: I) material designs for repairing the infarcted myocardium, considering the pathophysiological mechanism of MI and design principles for biomaterials in MI treatment; II) the development of injectable functional hydrogels for MI treatment, including conductive, self-healing, drug-loaded, and stimulus-responsive hydrogels; and III) research progress in using injectable hydrogels to restore cardiac function in infarcted myocardium by promoting neovascularization, enhancing cardiomyocyte proliferation, decreasing myocardial fibrosis, and inhibiting excessive inflammation. Overall, this review presents the current state of injectable hydrogel research in MI treatment, offering valuable information to facilitate interdisciplinary knowledge transfer and enable the development of prognostic markers for suitable injectable materials.
Comparative assessment of surgical myocardial revascularization using autoarterial and autove-nous conduits in patients with coronary artery disease: In-hospital results
Authors: Boyadzhyan Gevorg A. , Donakanyan Sergey A. , Shvartz Vladimir A. , Petrosyan Andrey D. , Koasari Anton K. , Sanakoev Merab K. , Ispiryan Artak Y. , Aygumov Rasul N. , Bockeria Leo A.
Published: March 2024

Objective: to evaluate the hospital results of coronary artery bypass grafting using autoarterial and au-tovenous conduits. Material and methods. A randomized clinical trial was conducted. The internal thoracic artery on the left was used in both groups (for shunting the anterior interventricular branch), the remaining conduits, depending on the distribution into groups, were either only the radial artery or the radial artery and the large subcutaneous vein (the study group) or only the large subcutaneous vein (the control group). The outcomes studied were: hospital mortality, myocardial infarction (type 5), cerebrovascular events, respiratory failure, bleeding, cardiac arrhythmias, acute kidney injury, etc. Results. 27 patients were randomized: 12 of whom were included in the study group, and 15 were included in the control group. According to operational and early postoperative data, there were no statistically significant differences between the groups, except for the duration of stay on a ventilator in the ICU: in the study group, the duration of a ventilator was longer than in the control group: 14 (12; 18) hours versus 9.3 (5.8; 13) hours, p=0.034. The most frequent complications were cardiac arrhythmias, as well as AKI. There were no statistically significant differences between the groups according to the outcomes studied. The bed-day after surgery also did not differ statistically significantly between the groups. Conclusion. According to the data obtained, it can be concluded that the first days after surgery, the use of the radial artery does not provide significant advantages compared to the use of a large saphenous vein.
Communication in virtual reality as applied to medical education
Authors: Meany Brendan , Fenn Jonathan , Rescober Stephanie , Narang Karamveer , Dhanda Jagtar
Published: March 2024

Virtual Reality (VR) has materialized as a technology enabling users to experience computer-generated 3D environments.1 Medical education programs have recently incorporated VR into their curriculum as a supportive means of experiential learning modalities like laboratory exercises and simulation training.2 Applying Kolb’s Experiential Learning Theory,3 the use of VR in medical education allows students to acquire knowledge and develop “soft skills” like collaboration, communication, and teamwork through interactive processes.2,4,5 Traditionally, medical training has occurred in siloed specialties instead of integrated practices that require coordination across disciplines to provide excellent patient care.6 While the efficacy and realism of VR have room for improvement, incorporating VR into experiential exercises can enhance non-technical skills such as interpersonal interactions, minimize medical error, democratize opportunities, and galvanizing diverse people and practitioners.6–9 This practical review briefly explains VR’s utility, its function as an experiential learning tool, and application in clinical exercises.