bluuebunny/crossref_metadata_2025 huggingface dataset:
Trends in acute ischemic stroke treatments and mortality in the United States from 2012 to 2018
Authors: Anand Sharath Kumar , Benjamin William J. , Adapa Arjun Rohit , Park Jiwon V. , Wilkinson D. Andrew , Daou Badih J. , Burke James F. , Pandey Aditya S.
Published: July 2021

OBJECTIVE

The establishment of mechanical thrombectomy (MT) as a first-line treatment for select patients with acute ischemic stroke (AIS) and the expansion of stroke systems of care have been major advancements in the care of patients with AIS. In this study, the authors aimed to identify temporal trends in the usage of tissue-type plasminogen activator (tPA) and MT within the AIS population from 2012 to 2018, and the relationship to mortality.

METHODS

Using a nationwide private health insurance database, 117,834 patients who presented with a primary AIS between 2012 and 2018 in the United States were identified. The authors evaluated temporal trends in tPA and MT usage and clinical outcomes stratified by treatment and age using descriptive statistics.

RESULTS

Among patients presenting with AIS in this population, the mean age was 69.1 years (SD ± 12.3 years), and 51.7% were female. Between 2012 and 2018, the use of tPA and MT increased significantly (tPA, 6.3% to 11.8%, p < 0.0001; MT, 1.6% to 5.7%, p < 0.0001). Mortality at 90 days decreased significantly in the overall AIS population (8.7% to 6.7%, p < 0.0001). The largest reduction in 90-day mortality was seen in patients treated with MT (21.4% to 14.1%, p = 0.0414) versus tPA (11.8% to 7.0%, p < 0.0001) versus no treatment (8.3% to 6.3%, p < 0.0001). Age-standardized mortality at 90 days decreased significantly only in patients aged 71–80 years (11.4% to 7.8%, p < 0.0001) and > 81 years (17.8% to 11.6%, p < 0.0001). Mortality at 90 days stagnated in patients aged 18 to 50 years (3.0% to 2.2%, p = 0.4919), 51 to 60 years (3.8% to 3.9%, p = 0.7632), and 61 to 70 years (5.5% to 5.2%, p = 0.2448).

CONCLUSIONS

From 2012 to 2018, use of tPA and MT increased significantly, irrespective of age, while mortality decreased in the entire AIS population. The most dramatic decrease in mortality was seen in the MT-treated population. Age-standardized mortality improved only in patients older than 70 years, with no change in younger patients.
Agreement of novel hemodynamic imaging parameters for the acute and chronic stages of ischemic stroke: a matched-pair cohort study
Authors: Sebök Martina , van Niftrik Christiaan Hendrik Bas , Wegener Susanne , Luft Andreas , Regli Luca , Fierstra Jorn
Published: July 2021

OBJECTIVE

In symptomatic patients with cerebrovascular steno-occlusive disease, impaired blood oxygenation level–dependent cerebrovascular reactivity (BOLD-CVR) and increased flow velocity of the P2 segment of the posterior cerebral artery (PCA-P2) on transcranial Doppler (TCD) ultrasonography have been introduced as emerging clinical imaging parameters to identify patients at high risk for recurrent ischemic events. Since hemodynamic physiology differs between the acute and chronic stages of ischemic stroke, the authors sought to investigate whether those parameters have merit for both the acute and chronic stages of ischemic stroke.

METHODS

From a prospective database, patients who underwent BOLD-CVR and TCD examinations in the acute stroke stage (< 10 days) were matched to patients in the chronic stroke stage (> 3 months). A linear regression analysis for both groups was performed between ipsilateral PCA-P2 systolic flow velocity and BOLD-CVR of the ipsilateral (affected) hemisphere, the ipsilateral middle cerebral artery (MCA) territory, and the ipsilateral steal volume (i.e., paradoxical BOLD-CVR response). The resulting slopes and intercepts were statistically compared to evaluate differences between groups.

RESULTS

Forty matched patient pairs were included. Regression analysis showed no significant difference for either the intercept (p = 0.84) or the slope (p = 0.85) between PCA-P2 flow velocity and BOLD-CVR as measured for the ipsilateral (affected) hemisphere. Similarly, no significant difference was seen between PCA-P2 flow velocity and BOLD-CVR of the ipsilateral MCA territory (intercept, p = 0.72; slope, p = 0.36) or between PCA-P2 flow velocity and steal volume (intercept, p = 0.59; slope, p = 0.34).

CONCLUSIONS

The study results indicated that the relationship between ipsilateral PCA-P2 systolic flow velocity and BOLD-CVR remains the same during the acute and chronic stages of ischemic stroke. This provides further support that these novel hemodynamic imaging parameters may have merit to assess the risk for recurrent ischemic events for a wide ischemic stroke population. PCA-P2 systolic flow velocity, in particular, may be a highly practical screening tool, independent of ischemic stroke stage.
Delays in presentation and mortality among Black patients with mechanical thrombectomy after large-vessel stroke at a US hospital
Authors: Catapano Joshua S. , Rumalla Kavelin , Srinivasan Visish M. , Nguyen Candice L. , Farhadi Dara S. , Ngo Brandon , Rutledge Caleb , Rahmani Redi , Baranoski Jacob F. , Cole Tyler S. , Jadhav Ashutosh P. , Ducruet Andrew F. , Albuquerque Felipe C.
Published: July 2021

OBJECTIVE

The incidence and severity of stroke are disproportionately greater among Black patients. In this study, the authors sought to examine clinical outcomes among Black versus White patients after mechanical thrombectomy for stroke at a single US institution.

METHODS

All patients who underwent mechanical thrombectomy at a single center from January 1, 2014, through March 31, 2020, were retrospectively analyzed. Patients were grouped based on race, and demographic characteristics, preexisting conditions, clinical presentation, treatment, and stroke outcomes were compared. The association of race with mortality was analyzed in multivariable logistic regression analysis adjusted for potential confounders.

RESULTS

In total, 401 patients (233 males) with a reported race of Black (n = 28) or White (n = 373) underwent mechanical thrombectomy during the study period. Tobacco use was more prevalent among Black patients (43% vs 24%, p = 0.04), but there were no significant differences between the groups with respect to insurance, coronary artery disease, diabetes, illicit drug use, hypertension, or hyperlipidemia. The mean time from stroke onset to hospital presentation was significantly greater among Black patients (604.6 vs 333.4 minutes) (p = 0.007). There were no differences in fluoroscopy time, procedural success (Thrombolysis in Cerebral Infarction grade 2b or 3), hospital length of stay, or prevalence of hemicraniectomy. In multivariable analysis, Black race was strongly associated with higher mortality (32.1% vs 14.5%, p = 0.01). The disparity in mortality rates resolved after adjusting for the average time from stroke onset to presentation (p = 0.14).

CONCLUSIONS

Black race was associated with an increased risk of death after mechanical thrombectomy for stroke. The increased risk may be associated with access-related factors, including delayed presentation to stroke centers.
Combined microsurgical-endoscopic paramedian supracerebellar-infratentorial approach for resection of a pineal low-grade glioma
Authors: Revuelta Barbero Juan M. , Soriano Roberto M. , Rindler Rima S. , Bray David P. , Henriquez Oswaldo , Solares C. Arturo , Pradilla Gustavo
Published: July 2021

The authors present the case of a 20-year-old male with a history of headaches and blurred vision found to have a pineal mass and chronic hydrocephalus. The patient initially underwent an endoscopic third ventriculostomy and pineal mass biopsy that revealed a low-grade neuroepithelial neoplasm. A microsurgery-endoscope–assisted paramedian supracerebellar-infratentorial approach was chosen and a gross-total resection was achieved. The patient’s postoperative and follow-up course has been unremarkable, with early postoperative imaging demonstrating no residual tumoral mass. The operative video highlights the advantages of endoscopic visualization for deep lesions in the pineal region and posterior third ventricle.

The video can be found here: https://stream.cadmore.media/r10.3171/2021.4.FOCVID2119.
Occipital interhemispheric transtentorial approach to a pineoblastoma in a 4-year-old child
Authors: Imperato Alessia , Marini Alessandra , Spennato Pietro , Mirone Giuseppe , Cinalli Giuseppe
Published: July 2021

The authors present a pediatric case of a pineoblastoma treated with gross-total removal through an occipital interhemispheric transtentorial approach (OITA). The child presented with acute hydrocephalus that was treated by endoscopic third ventriculostomy (ETV) and tumor biopsy through a single burr hole. Histology revealed a pineoblastoma. Microsurgical total removal was performed 3 months after neoadjuvant chemotherapy. OITA was chosen on the basis of the tumor’s location below the Herophilus-Galen line of sight. In this video, the authors show the positioning, the operating devices, the approach, and the microsurgical dissection, indicating all the neurovascular structures encountered.

The video can be found here: https://stream.cadmore.media/r10.3171/2021.4.FOCVID2122.
Meningioma of posterolateral tentorial incisura: a case demonstration of paramedian supracerebellar transtentorial approach
Authors: Keles Abdullah , Ozaydin Burak , Baskaya Mustafa K.
Published: July 2021

The paramedian supracerebellar transtentorial approach allows unobstructed exposure to the quadrigeminal cistern, tectal plate, pineal region, tentorial incisura, medial basal temporal lobe, and posterior ambient cistern. The authors present a meningioma of the posterolateral tentorial incisura case in a 62-year-old male who presented with a long history of upper-extremity tremors and walking difficulties. MRI revealed supra- and infratentorial tumor extension and hydrocephalus. This approach enabled us to achieve gross-total resection without causing neurovascular injury or any postoperative neurological deficits. For each pathology, the pros and cons of various approaches should be considered based on the anatomy, vasculature, and any surrounding structures.

The video can be found here: https://stream.cadmore.media/r10.3171/2021.4.FOCVID2138.
Anterior endoscopic transcortical approach to a pineal region cavernous hemangioma
Authors: Li Jiuhong , He Jiaojiang , Liu Lunxin , Zhou Liangxue
Published: July 2021

A 57-year-old female presented with headache and dizziness for 3 months. Preoperative MRI revealed a lesion located at the pineal region and back side of the third ventricle, accompanied by hydrocephalus. The infratentorial supracerebellar approach may cause visuomotor, acousticomotor, and hearing disturbances. With the patient in a supine position, the authors used a frontal linear incision that was 3 cm anterior to the coronal suture and 2 cm away from the midline and an anterior endoscopic transcortical approach, which could achieve endoscopic third ventriculostomy, alleviating and preventing hydrocephalus due to postoperative adhesion and resection of the lesion at the same time. The pathological diagnosis was cavernous hemangioma.

The video can be found here: https://stream.cadmore.media/r10.3171/2021.4.FOCVID215.
Depression, Anxiety and Stress among Nepali Health Care Workers during the Coronavirus Disease 2019 Pandemic: A Cross-sectional Survey
Authors: Sharma Ishwor , Misra Anurag , Kumar Shrestha Bipin , Kumar Koirala Arun , Banjade Anita , Banjade Prakash
Published: July 2021

Introduction: Studies among health care workers from different part of world during the coronavirus disease 19 pandemic have reported substantial impact on their physical, mental and emotional well-being. This study measured the impact of coronavirus disease 2019 on the mental health of Nepali healthcare workers in different parts of the world during the pandemic.
Methods: This cross-sectional survey was carried out from December 25, 2020 to Jan 25, 2021. Ethical approval was taken from the Institutional Review Committee (reference number: 372). Online questionnaire including demographic profiles and Depression, Anxiety, and Stress Scales-21 instrument were sent to Nepali healthcare workers around the world through social media apps using convenience sampling. Data were entered into Microsoft Excel for Mac version 16.49 and analysed.
Results: Among 208 who participated in the study, 62 (30%) participants were positive for anxiety, 47 (22.5%) for depression and 25 (12%) for stress. Higher prevalence of depression 18 (30%) and stress 10 (17%) was found in nurses compared to paramedics, among whom depression was seen in 5 (20%) and stress in 4 (16%). Among doctors, depression was found in 24 (19%) and stress in 11 (9%).
Conclusions: This study demonstrated that a high proportion of healthcare workers were suffering from depression, anxiety and stress. Our findings are similar to the data from other national and international studies.
KELAYAKAN MULTIMEDIA PEMBELAJARAN INTERAKTIF DALAM MEMOTIVASI SISWA BELAJAR MATEMATIKA
Authors: Kusumawati Lilis Diah , Sugito NFn , Mustadi Ali
Published: July 2021

Interactive multimedia is a technology that mediates the development of learning activities to make it more interesting and enjoyable so that it can motivate students to learn. This study aims to determine feasibility of interactive learning multimedia product in motivating student for fourth grade of elementary school to learn mathematics. The research method uses the concept of ADDIE models to develop products with five stages, 1) analyze; 2) design; 3) develop; 4) implement; and 5) evaluate. The result showed that the development of interactive learning multimedia is feasible used for motivating students in grade 4 to learn mathematics. The result of validation by material experts showed that the products developed reached a score of 43 so that it was included in the "very good" category, while the results of the validation by the media experts showed that the products developed reached a score of 59 so that it was included in the "very good" category. Teacher responses related to the practicality of product use reached a score of 113 so that it was included in the "very good" category, while student responses related to the practicality of using the product reached a score of 83 so that it was included in the "very good" category. In motivating students to learn mathematics, interactive learning multimedia can be applied to elementary school students in grade 4.AbstrakMultimedia interaktif adalah teknologi yang memediasi pengembangan kegiatan pembelajaran agar lebih menarik dan menyenangkan sehingga mampu memotivasi siswa dalam belajar. Penelitian ini bertujuan untuk mengetahui kelayakan produk multimedia pembelajaran interaktif dalam memotivasi siswa kelas IV sekolah dasar untuk belajar matematika. Metode penelitian menggunakan konsep model ADDIE untuk mengembangkan produk dengan lima tahap, 1) menganalisis; 2) desain; 3) berkembang; 4) mengimplementasikan; dan 5) mengevaluasi. Hasil penelitian menunjukkan bahwa pengembangan multimedia pembelajaran interaktif layak digunakan untuk memotivasi siswa kelas 4 dalam belajar matematika. Hasil validasi oleh ahli materi menunjukkan bahwa produk yang dikembangkan mencapai skor 43 sehingga masuk dalam kategori “sangat baik”, sedangkan hasil validasi oleh ahli media menunjukkan bahwa produk yang dikembangkan mencapai skor 59 sehingga masuk dalam kategori "sangat baik". Tanggapan guru terkait dengan kepraktisan penggunaan produk mencapai skor 113 sehingga masuk dalam kategori “sangat baik”, sedangkan respons siswa terkait dengan kepraktisan penggunaan produk mencapai skor 83 sehingga masuk dalam kategori “sangat baik”. Dalam memotivasi siswa untuk belajar matematika, multimedia pembelajaran interaktif dapat diterapkan untuk siswa sekolah dasar di kelas 4.
Peranan Guru Bimbingan dan Konseling dalam Pembentukan Karakter Siswa di SMP Negeri 36 Palembang
Authors: Syahdana Anisa , Nurlela Nurlela
Published: July 2021

Penelitian ini bertujuan untuk mengetahui peranan guru bimbingan dan konseling dalam pembentukan karakter disiplin siswa di SMP NEGERI 36 Palembang.Penelitian ini menggunakan pendekatan kualitatif deskriptif. Peneliti menggunakan metode pengumpulan data berupa wawancara dan dokumentasi penentuan informan dalam penelitian ini menggunakan teknik sampling purposive. Informan dalam penelitian ini yaitu wakil kesiswaan, guru wali kelas, guru bimbingan dan konseling dan satu orang siswa kelas VII. Hasil penelitian ini menunjukan peran guru bimbingan dan konseling dalam pembentukan karakter disiplin siswa cukup berjalan dengan baik. Guru bimbingan dan konseling berkolaborasi dengan wakil kesiswaan, guru wali kelas, dan orang tua untuk menyelesaikan permasalahan siswa yang kurang disiplin. Siswa yang kurang disiplin diberikan layanan konseling individual dan guru bimbingan dan konseling juga melakukan kunjungan kerumah siswa untuk mencari tahu faktor penyebab siswa tersebut kurang disiplin dan membicarakan permasalahan siswa disekolah kepada orang tua siswa.Â
Studi Kasus Ppda Siswa yang Memiliki Perilaku Pacaran Menyimpang di SMP Negeri I Madang Suku II
Authors: Sri Astuti Ayu , Romli Moh. Edwar
Published: July 2021

Dikalangan remaja sering dijumpai adanya perilaku pacaran menyimpang, perilaku pacaran menyimpang hasil dari proses sosialisasi yang tidak sempurna. Kelompok yang paling rentang dalam proses prilaku pacaran menyimpang yaitu para remajaTujuannya peneliti untuk megetahui bentuk-bentuk siswa yang memiliki perilaku pacaran menyimpang, mengetahui faktor sisiwaÂ  yang memiliki perilaku pacaran menyimpang, mengetahui dampak dari siswa yang memiliki perilaku pacaran menyimpang, mengetahui peran guru BK dalam mengatasi siswa yang memiliki perilaku pacaran menyimpang. Jenis penelitian yang dilakukan pada penelitian ini adalah jenis penelitian kualitatif dengan metode pengumpulan datanya menggunakan fiel research (penelitian lapangan) yaitu peneliti dengan mengamati langsung ke lokasi penelitian atau subyek yang akan diteliti. subyeknya secara langsung dan melalui pengamatan. Setelah semua data yang diperlukan telah terkumpul, lalu dianalisis. Teknik analisisnya dengan cara reduksi data, penyajian data, dan verifikasi.Hasil penelitian adalah bentuk perilaku pacaran menyimpang bersentuhan,berciuman,berpelukan. Faktor keluarga, kelompok bermain, media masa. Dampak prestasi sekolah menurun, pergaulan sekolah, mengisi waktu luang, perasaan nyaman dan peran guru BK.Â Kata kunci : Siswa x Yang Memiliki Perilaku Pacaran Menyimpang
Emotion Focused Coping dalam Mereduksi Kecemasan pada Masa Pandemi Covid-19
Authors: Indra Syaiful , Ayuningtiyas Dian , Pohan Rizky Andana
Published: July 2021

Pandemi Covid-19 membuat tatanan kehidupan manusia terganggu akan kedatangannya. Dampak yang ditimbulkan oleh pandemi covid-19 memaksa individu dalam bersikap adaptif pada kondisi psikologis. Berbagai persoalan psikologis muncul akibat pandemi covid-19, tidak semua individu mampu bertahan dengan kondisi yang baik. Fenomenanya tidak semua individu memiliki kemampuan resiliensi yang memadai, sehingga akan berdampak pula pada kecemasan. Kecemasan akan timbul apabila ada peristiwa buruk yang dialami oleh individu yang belum terselesaikan. Gangguan psikologis yang muncul disebabkan oleh kecemasan dapat terefleksi pada behavior, kognitif, dan fisik. Oleh sebab itu kecemasan sepatutnya perlu adanya penangan atau terapi khusus untuk mereduksi dampak yang muncul. Salah satu variabel yang dapat mereduksi kecemasan adalah emotion focused coping. Emotion focused coping merupakan suatu tindakan untuk mengurangi tekanan psikologis yang muncul oleh stressor. Naskah ini akan mendeskripsikan emotion focused coping dalam mereduksi kecemasan pada masa pandemi covid-19.Â
MAQĀṢID AL-SYARĪ’AH DALAM TINJAUAN PEMIKIRAN IBNU ‘ĀSYŪR DAN JASSER AUDA
Authors: Ni’ami Mohammad Fauzan , Bustamin Bustamin
Published: July 2021

This paper examines the comparative maqāṣid al-syarī’ah in the thoughts of ibn 'āsyūr and jasser auda, preceded by examining the construction of maqāṣid  al-syarī’ah thinking of ibnu' āsyur and jasser auda which contains the background of thought, maqāṣid  al- theory. shārī 'ah, and the method of determining the maqāṣid  al-syarī’ah. This paper also analyzes the advantages and disadvantages of the similarities and differences between the maqāṣid  al-syarī’ah which was initiated by Ibn 'Āsyūr and Jasser Auda. Not to forget that this type of research is library research using a comparative approach. The results show that the similarities of maqāṣid  al-syarī’ah ibnu āsyūr and jasser auda both make constructive criticism of the traditional model maqâsid for various reasons, while the difference is that the concept of maqāṣid asy-syarīʻah is offered with their background backgrounds. The weaknesses of the maqāṣid al-syarī'ah Ibn 'Āsyūr are that the big idea is still the same as that of Imam al-Shāṭibī such as the method of istiqrā' and the way of expressing the aims of shari 'by paying attention to the form of amar, nahi which has a clear start, while the lack of maqāṣid al-syarīʻah Jasser Auda is in the author's opinion setting aside the turast tradition.
El interés emancipador de la ciencia contable. Un recorrido epistemológico
Authors: Amézquita Medina Claudia E.
Published: July 2021

Esta breve mirada epistemológica sobre los horizontes ontológicos de la contabilidad pretende desentrañar determinadas convicciones de fondo, inobservables, de tipo filosófico que permitan fundamentar la contabilidad como la ciencia universal del bien común, en desarrollo de la tesis doctoral en ciencias contables de la Universidad de los Andes de Mérida - Venezuela. Se busca el camino hacia la fundamentación y la legitimación de los saberes desde la praxis del sujeto contable, evidenciando experiencias y razones para el cumplimiento de los preceptos de autenticidad, rectitud y veracidad; en las que se libera de los paradigmas racionalistas y lógicos que ha desarrollado la modernidad en el SXX.Con ayuda de la hermenéutica y la fenomenología se pretende visualizar el horizonte de percepción ontológica y gnoseológica; y a la vez, ha de convertirse en el método, como instrumento emancipador de la técnica contable para garantizar el bien común.
Is it of any positive being COVID-19 positive?: Cross-protection hypothesis
Authors: Alser Muath
Published: July 2021

Many pathogens have been reported to induce cross-protective immune responses against other related and unrelated pathogens due to shared epitopes or induction of trained immunity.

Herein, I review the evidence we have so far on the possible SARS-CoV-2 cross-reactions with other pathogens, and the immune modulatory effects it could induce, which could lead to beneficial effects against other diseases among COVID-19-recovered immunocompetent individuals.
Metacognición y resolución de problemas en niños escolarizados
Authors: Cerchiaro Ceballos Elda , Barras Rodríguez Rafael Antonio , Breidis Nayely Curiel Gómez Breidis Nayely , Bustamante Meza Lucía Yesenia
Published: July 2021

La investigación sobre metacognición indica que la capacidad para comprender, reflexionar y controlar los procesos cognitivos favorece la resolución de problemas en niños. El presente estudio analiza la relación entre las habilidades metacognitivas y el desempeño de niños escolarizados en la Torre de Hanoi (ToH), en una muestra conformada por 30 niños y niñas entre 9 y 11 años. La ToH fue presentada en una versión digital de cuatro discos para ser jugada en un computador, permitiendo registrar número de movimientos, de errores y tiempo empleado. Se utilizó un cuestionario de auto reporte para explorar los procesos metacognitivos de planificación, seguimiento y evaluación en la resolución del problema. Los resultados indican correlaciones positivas significativas entre el desempeño de los niños en la ToH y los funcionamientos metacognitivos de seguimiento y evaluación. Se halló también que los participantes con mejor desempeño realizaron más movimientos y menos errores. Estos resultados representan un nuevo aporte al análisis de la relación entre metacognición y las estrategias de los niños para la resolución de problemas.
Pengelolaan Alokasi Dana Desa untuk Pengembangan Pembedayaan Masyarakat di Desa Panggungharjo
Authors: Aqsati Farah Aruni
Published: July 2021

The purpose of this study is to determine the accountability in terms of planning, management, and accountability of village funds in Panggungharjo Village, Sewon District, Bantul Regency. In addition, it is also to find out the development and empowerment of potential communities in Panggungharjo Village. This research is a qualitative descriptive study through methods of data collection, data reduction and data presentation. Village fund planning is carried out together with the APBDes report and submission of the RAPDes from the village to the district. Management is carried out through meetings between the village head, village secretary, financial division, and development division. The accountability of village fund management is submitted with the APBDes report by the Village Head to the District Head. It then is forwarded from the District Head to the Head Regency of Bantul based on the existed regulation. Developing the potency of the community in Panggungharjo Village includes the establishment of activity units such as BUMDes Panggung Lestari, Bapel JSM, SADEPA, Bumi Panggung and Pakarti.
Percepções sobre o uso de plantas medicinais por profissionais de áreas rurais e urbanas em cidade no nordeste do Brasil
Authors: Nascimento Júnior Braz José do , Lima Fernanda Maira Gomes Andrade , Rocha Carlos Ramon da Anunciação , Gonçalves Rosy Kátia Souza , Souto Lidione Brito , Vieira Denes Dantas
Published: July 2021

O uso de plantas medicinais é uma prática popular aceita por alguns profissionais da saúde. O objetivo desse estudo foi saber se os médicos, cirurgiões-dentistas e enfermeiros das unidades de saúde do município de Juazeiro-Bahia têm o conhecimento e percebem a importância da utilização e das indicações das plantas medicinais e dos fitoterápicos. Trata-se de um estudo transversal, exploratório e descritivo no qual participaram 56 profissionais de nível superior. Os dados foram obtidos através de entrevista individual, usando-se um formulário semiestruturado. Adotou-se para a análise estatística, o teste de Pearson qui quadrado, com nível de significância de p<0,05. Como resultado, observou-se que 30 (53,57%) profissionais disseram não saber orientar os pacientes sobre a utilização de plantas medicinais e que o conceito de fitoterápicos e a diferença em relação aos homeopáticos não estavam claros para alguns. As plantas mais citadas pelos médicos foram Valeriana officinalis L. e Matricaria recutita L., pelos enfermeiros foram Plectranthus barbatus A. e Passiflora edulis S. e pelos dentistas foram Punica granatum L. e Mentha piperita L. Conclui-se que os profissionais do município necessitam de capacitação sobre essa alternativa terapêutica.
Variação intraespecífica na composição e teor do óleo essencial de Lippia thymoides
Authors: Baier Krepsky Patrícia , Suellen Caires Neves Dilaine , Nunes Santana Gabriela
Published: July 2021

Lippia thymoides é uma planta aromática e medicinal nativa na Caatinga e Cerrado brasileiros. Pesquisas foram realizadas nas áreas de farmacologia e fitoquímica, no entanto, o conhecimento científico sobre a variação química é inceptivo. Portanto, esta pesquisa teve como objetivo avaliar possíveis fatores que interferem no teor e composição química do óleo essencial de folhas e flores. Para determinação do teor de óleo essencial foi empregado aparelho de Clevenger. O óleo essencial obtido foi avaliado por cromatografia gasosa acoplada a espectrômetro de massas. As variáveis foram: diferentes indivíduos (seis) e horários de coleta (7, 12 e 17 horas), recuperação após poda e estresse hídrico em campo. O horário de coleta, a poda e a seca não influenciaram o teor de óleo essencial. Foi detectada apenas variação interindividual. A análise da composição química do óleo essencial revelou timol, metiltimol e p-cimeno como componentes majoritários. Algumas variações foram observadas na composição dos óleos essenciais, porém o perfil cromatográfico permaneceu constante. Portanto, a coleta pode ser realizada a qualquer hora do dia, e uma nova coleta pode ocorrer após a recuperação da planta sem comprometer o teor de óleo essencial e sua composição química.
Capacidade de formação de biofilme por cepas bacterianas e ação antibiofilme do extrato de Lafoensia pacari (Lythraceae)
Authors: Pavão Danilo Pavão e , Moraes Francyelle Costa , Ribeiro Brendha Luanny Moreira , Costa Flávio Guilherme Rodrigues , Camara Marcos Bispo Pinheiro
Published: July 2021

Nos últimos anos surgiram inúmeros microrganismos multirresistentes. Um especial mecanismo que confere resistência à antibióticos e sistema imune é a capacidade de formar biofilme. Essa estrutura é um aglomerado de bactérias envolvidas por uma matriz polimérica que as protege. O presente estudo buscou quantificar e classificar a produção de biofilme por microrganismos frequentemente encontrados em Infecções Relacionadas a Assistência à Saúde (IRAS) e de linhagens isoladas de uma Unidade de Terapia Intensiva (UTI), além de testar a atividade antibiofilme do extrato das folhas da Lafoensia pacari. Utilizou-se o método de quantificação de biomassa com cristal violeta e leitura a 570nm. Obteve-se maior produção de biofilme por bactérias do grupo das gram-negativas como Pseudomonas aeruginosa isolada de um colchão e entre as gram-positivas destaca-se a E. faecalis (ATCC 19429). O extrato vegetal teve ação antibiofilme em 50% dos microrganismos testados, inclusive entre os mais fortes formadores de biofilme.
DIRECTIONS AND TOOLS OF THE ECONOMIC MECHANISM OF STATE REGULATION OF MIGRATION PROCESSES IN UKRAINE
Authors: Vasyltsiv Taras , Mulska Olga
Published: July 2021

The article focuses on the problematic aspects and negative effects of increasing the external migration in Ukraine. The necessity of improving the modern migration policy is substantiated. The directions of the economic instrument of regulation of external migration are offered: slowing down of rates of external migration at the expense of improvement of an employment policy and creation of new workplaces; development of the micro and small business sector using the potential of external labour migrants; increasing the level of readiness of migrants for re-emigration by improving institutional capacity and assisting in the establishment of problematic social, labour and other aspects of migrants abroad; increase in investments in the economy at the expense of external labour migrants; preservation of human potential using the regulation of external educational migration. It is proved that the implementation of state policy measures (creation of conditions for legalization of sectoral labour markets by a high level of informal employment; support of non-standard forms of formal legal employment, development of the intermediary sector in the labour market; initiation of development and implementation of employment programs; preparation of ‘turnkey businesses’, implementation of programs to improve the availability of financial and credit resources for micro and small businesses, the creation of urban venture funds to invest in creative, innovative and technological business projects, start-ups of micro and small business, organizational and resource support for organizations specializing in maintaining ties with the diaspora, grants to NGOs to create and support the operation of Internet platforms, stimulating the creation of special bank deposit programs for migrant workers, resource which is used as a guarantee of financial and credit support for micro and small businesses; introduction of grant programs to support entrepreneurship for certain groups of the population – migrants, internally displaced persons, youth) would minimize risks, control the process of intensification of external migration flows in Ukraine.
SYSTEM ECONOMIC DYNAMICS OF PASSENGER AIR TRANSPORT AND INSTITUTIONAL MECHANISMS OF ITS REGULATION
Authors: Smerichevskyi Serhii , Gura Svitlana
Published: July 2021

In the article the system dynamics as a method of studying complex hierarchical systems is applied to the diagnosis of the state and development of passenger air transport in Ukraine during 2010-2020 to clarify the causal quantitative, qualitative, structural changes. The rapid, linear, uniform growth of air passenger traffic in Ukraine during 2015-2019, associated with the signing of the Association Agreement with the EU, has been established. The following 2020 has been identified as a bifurcation point that has reversed a steady upward trend to a sharp threefold decline in passenger traffic due to restrictive measures to counter the spread of COVID-19. Intensive processes of concentration in passenger air transport were revealed, as the growth of passenger turnover took place against the background of a reduction in the number of enterprises and an even greater rate of reduction of employment in the industry. The distribution of the number of employees, services provided, value added created, financial results obtained by size of enterprises is exponential, as the vast majority of them are large enterprises, the share of which is small. The general estimation of development of passenger air transport is carried out on the criterion of financial results. Its shortcomings are: the presence of systemic losses during 2010-2014, a significant number of unprofitable enterprises, the positives – profitable activities at the industry level in 2019, the growing trend of the share of profitable enterprises. The content of institutional mechanisms for regulating the development of passenger air transport enterprises, represented by the management of social and labor relations in the industry, the introduction of customer-oriented approach and promising technologies for passenger air service development, strengthening guarantees of consumer protection, interaction with European and global transport systems. It is shown that the institutional mechanisms of regulation of passenger air transport should not be based on state protectionism, but on the criterion of increasing the efficiency and competitiveness of air transport market entities within the framework of the «open skies» policy.
Ecology, phenology and wintering behavior of Anatidae in the wetlands of Souk–Ahras (north–eastern Algeria)
Authors: Bouali N. , Baaloudj A. , Touarfia M. , Houhamdi I. , Maazi M. C. , Houhamdi M.
Published: July 2021

Understanding the spatial and temporal niche of waterfowl is essential for effective management and conservation. To determine the ecology and phenology of Anatidae in North Africa, we carried out a 12–month study (2019–2020) in three wetlands that constitute a winter refuge for waterbirds in the Souk–Ahras region in north–east Algeria. We surveyed species richness, the seasonal pattern of the number of Anatidae, and their wintering diurnal behavior using regular counts and scans. We recorded thirteen species: six wintering species (Anas clypeata, Anas penelope, Anas strepera, Tadorna tadorna, Aythya ferina, and Anas crecca crecca) and three sedentary nesting species (Anas platyrhynchos, Oxyura leucocephala, and Aythya nyroca), the latter two having national and international protection status. The survey showed that the wintering behavior of all these species is dominated by sleep, which on average accounts for almost half of the total time (48.91 %). Our results indicate that the three wetlands host a complex waterfowl community that includes species of conservation concern and that these sites likely play an essential role in providing the essential resources for wintering. Dataset published through GBIF (Doi: 10.15470/fozdot)
ANALYSIS OF THE CURRENT STATE OF FUNCTIONING OF WATER TRANSPORT ENTERPRISES OF UKRAINE AND THE WORLD
Authors: Tymchenko Nadiia , Kuzmenko Olena , Kuzmenko Valentyn
Published: July 2021

This article is dedicated to the study of the market of freight and passenger transportation by water in the world and Ukraine in order to identify the prevailing trends in the industry. The statistical data and scientific works of domestic and foreign scientists on the current functioning and prospects of water transport were the main basis of the study. The authors analyzed the volume of freight transport by water, identified the main transportation routes and the distance thereof, and the development of maritime transport in different countries was analyzed as well. In the course of study the components affecting the efficiency of water transport enterprises, and generate the indicators of the development rate thereof in particular countries.
It is established in this work that it is possible to assess the state of development of Ukrainian maritime transport on a global scale using the Global Competitiveness Index, which is generated according to the methodology of the World Economic Forum, in particular, water transport is assessed on two indicators: integration into the international transportation routes and port efficiency.
The authors performed a comparative analysis of the Global Competitiveness Index in different countries, which convincingly proves the need for development of transport infrastructure of a state, which is part of the overall infrastructure development in the country.
In this work the main problems of the transport industry development are identified, the factors of negative impact on the state and prospects of river and maritime transport enterprises of Ukraine, including obsolescence or lack of navigational infrastructure, and lack of a systematic approach to water logistics construction, and obsolescence and insufficiency of the fleet, and the lack of qualified personnel in the industry, as well as the lack of state regulation and the lack of state support; unsatisfactory investment climate in the country as a whole, the complexity of registration and high cost of international cabotage in both sea and river water areas of Ukraine, etc.
The authors substantiated the ways of counteracting the identified factors and defined the directions of development of water transport enterprises, as well as measures proposed separately for river and maritime transport.
HOSPITALITY MANAGEMENT AS A PREREQUISITE OF EFFECTIVE TOURISM DEVELOPMENT IN UKRAINE
Authors: Khytra Olena
Published: July 2021

The hospitality industry acquires the features of an integrative industry, which combines material resources and intangible factors to meet the needs of modern man for comfortable travel and recreation. Hospitality is interpreted as a complex economic, social, cultural, psychological phenomenon, the impact of which on the development of the tourism industry determines the effect of synergy from the combination of tourist resources and quality of service. The author of article proposes to consider hospitality management as a multilevel dynamic management system for the process of providing services to tourists and vacationers, based primarily on the principles of humanism, tolerance, personalization of hospitality, respect for cultural diversity, priority to meet human needs for quality recreation and physical strength as well as cultural self-development. The social orientation of this system to some extent balances the commercial, purely pragmatic aspect of managing the development of tourism enterprises. A holistic model of hospitality management is based on a harmonious combination of four concepts. They are humanitarian, technological, functional and commercial. The system-forming component of the hospitality sector is a mechanism for managing consumer behaviour, which ensures an optimal balance of supply and demand in the market of hospitality services. The specifics of service in the hospitality industry is that the quality of service affects the emotional perception of tourists in the area and, accordingly, affects the image of the state. Therefore, the mechanism for implementing the service policy should be established through public administration measures. Among the key areas of hospitality management development is the formation of a rational organizational structure, improvement of hospitality marketing and support of corporate culture, the values of which are adequate to the socio-cultural environment of the hospitality industry. The specificity of the hospitality industry is also that an important role in ensuring competitiveness is played by an attractive brand, which stipulates the allocation in the management system of such a component as brand management. Considerable attention should be paid to the innovative development of hospitality enterprises and the constant improvement of professional competence of managers of socio-cultural activities.
APPLICATION OF THE PRINCIPLES OF GENDER EQUALITY IN THE PLANNING OF BUDGET EXPENDITURE AND INCOME IN UKRAINE
Authors: Pryimak Iryna , Muntian Iryna
Published: July 2021

The article clarifies the essence and benefits of gender-oriented budgeting. The problem of lack of legislative consolidation of the use of GOB in the budget process is considered, which is one of the main reasons for slowing down the process of implementation of this method and approval of methods for its implementation. Indicators of gender statistics, in particular the city of Lviv, such as the structure of the permanent population by gender, unemployment rate by age and gender, mortality rates by cause and gender, social groups of internally displaced persons (IDPs) and the problems they most often face depending on gender are analyzed. It was found that the situation of women in most areas is worse than men, and in modern conditions during the pandemic situation only gets worse. Given recent world events, the need for a public financial management system that takes into account the impact of gender measures to overcome the coronavirus pandemic is justified. A correlation analysis of gender impact on tax revenues of budgets on the basis of indicators that directly affect tax revenues to budgets by gender such as the average monthly wages of women and men in Ukraine for the period 2012-2019, as well as the number of women and men PE and their income for the period 2016 - 2020 has been conducted. The reasons for the reported results of the analysis are substantiated and explained, taking into account all possible factors. It is clear how the closure of “sleeping” private enterpreneurs, which has been observed since 2016, has affected the indicator of the total number of private enterpreneurs and their income indicators, which directly affect tax revenues to local budgets. The influence of these indicators on the formation of revenue and expenditure components of the budget based on the results of their statistical and correlation analyzes is estimated. The article confirms the opinion that the results of gender budget analysis help to make decisions on the directions of budget policy and development of industries in the future, taking into account the needs of men and women from different groups. As a result, it makes it possible to eliminate inequality in access to services financed from the local budget in the indicated areas.
CHANGING THE PARADIGM OF MODELING AND FORECASTING SOCIO-ECONOMIC SYSTEMS
Authors: Kolomiiets Svitlana , Dinits Ruslan
Published: July 2021

Modern socio-economic systems demonstrate instability, chaos, and unpredictability. What methodology should be used to modeling modern socio-economic systems? Constant changes and crises in the development of socio-economic systems require new approaches to the research of these systems. The feature of the approach to the study of socio-economic systems in modern conditions is the conversion from a linear to a nonlinear paradigm.
The models of socio-economic systems are systems of nonlinear differential equations. Nonlinear differential equations demonstrate different modes of functioning of complex socio-economic systems. Nonlinear equations can have several qualitatively different solutions. This explains the existence of different ways of evolution of nonlinear socio-economic systems.
Nonlinearity is a fundamental position of new paradigm of cognition and development. Nonlinearity is a general law of nature and means, first of all, non-observance of the principle of superposition. The whole cannot be the sum of its parts; the result cannot be the sum of efforts, the quality of the whole is not determined by the sum of the qualities of its parts, the reaction of the system is not proportional to the influence.
For nonlinear phenomena, knowledge about the behavior of a part of an object does not yet guarantee correct ideas about the behavior of the object as a whole, and its response to changes in conditions may qualitatively depend on the magnitude of these changes.
Non-linearity is the multivariance of the evolutionary paths, the presence of a choice of alternative paths and determining the rate of evolution. Nonlinearity is the irreversibility of evolutionary processes; nonlinear, indirect dependence of evolutionary processes on external influences.
The article examines the topical issue of changing the paradigm of modeling and forecasting socio-economic systems. The necessity of transition from linear to nonlinear paradigm in economic research is theoretically substantiated. The features of the application of methods of nonlinear dynamics to the modeling of socio-economic systems are considered. The phenomenon of nonlinearity of socio-economic systems is studied.
DEVELOPMENT OF THE ENTERPRISE`S ECONOMIC SECURITY ENSURING SYSTEM IN THE CONDITIONS OF THE CHANGING ENVIRONMENT
Authors: Hviniashvili Tetiana , Khaletska Viktoriya
Published: July 2021

The article provides theoretical and practical recommendations for improving the state of economic security in the enterprise in a changing environment.The origin of the concept of "enterpriseeconomic security" was studied and information on the basic concepts of economic security was provided.The main problems of ensuring the desired level of economic security at domestic enterprises were also considered, the use of clear methods for developing an effective system of economic security was proposed and the structure and stages of monitoring the state of economic security of the enterprise as a whole were given.The proposed monitoring system allows focusing on such phenomena and processes as the selection of the most important elements of the economic security of the enterprise and determining the composition, structure, methods of assessing the effectiveness of the organization's internal control system, risk management methods and methods of eliminating threats to safe operating of business entity. Information was also provided on how to implement an effective mechanism for the operation of the internal cost control service for business entity to improve its overall security. Recommendations were provided for small, medium-sized and large enterprises on the feasibility of creating a separate unit of economic security and recommendations for the formation of an individual risk and threat management system for each business entity. The paper proved that economic security is a complex indicator that is affected by many risks and threats of the enterpriseexternal and internal environment. Sources of these risks may include sources of negative impact, which are related to the financial situation in the market, technological innovations and scientific discoveries, force majeure, etc. In order to comprehensively monitor and control the activities of the enterprise it is necessary to develop a system of indicators of economic security for certain components, which determines the direction of further research in this area.