bluuebunny/crossref_metadata_2025 huggingface dataset:
A Comparative Analysis of the Evaluation Techniques of Capital Budgeting in E-Commerce
Authors:   Multimedia Engineering Department, Hannam University, Daejeon, South Korea, Bharti Preeti , Hossain Md. Rajib ,   Multimedia Engineering Department, Hannam University, Daejeon, South Korea, Islam Md. Rakibul ,   Multimedia Engineering Department, Hannam University, Daejeon, South Korea
Published: May 2024

E-commerce has grown exponentially as the digital revolution reaches its peak. Most business transactions nowadays have the option of being done electronically or online through the Internet. In this growing field of e-commerce and with the increasing number of potential investments, intensive evaluation of a profitable proposal is essentially necessary in order to increase the value of the firm and avoid losses if possible. This paper aims to analyze the different e-commerce capital budgeting evaluation techniques by critiquing their formulas and identifying the corresponding advantages and disadvantages of using them. An introduction to capital budgeting and the key processes involved will also be presented.
Documents Component Ontology (DoCO): Laguna University Accreditation Tool
Authors:   Department of Information Technology, Laguna University, Sta. Cruz Laguna, Philippines, Atanacio Marlon , Fucio Chrisna ,   Department of Information Technology, Laguna University, Sta. Cruz Laguna, Philippines, Matute Alejandro ,   Department of Information Technology, Laguna University, Sta. Cruz Laguna, Philippines
Published: May 2024

The document layers’ representation, arrangement, and discourse in machine-readable survey forms are pivotal for both users and machines in organizing and understanding the documents. In this endeavor, the researchers instituted DoCO, the Document Components Ontology for the Accreditation of Laguna University. This is the classification that gives an all-purpose organized file elements’ vocabulary to chronicle units of a document. As a result of the overall assessment of the respondents and clients in terms of Functional Suitability, Performance Efficiency, Compatibility, Usability, Reliability, Security, Maintainability, and Portability which got 4.12 as the overall weighted mean, which is verbally interpreted as “Good.” The respondents perceived the developed project as effective because it could give quick, valid, and fixed information. This can be utilized for the accreditation purposes of the institution.
Emergency Number Services Rescue Mobile App in Sta. Cruz, Laguna
Authors:   Department of Information Technology, Laguna University, Sta. Cruz, Laguna, Philippines, Atanacio Marlon , Fucio Chrisna ,   Department of Information Technology, Laguna University, Sta. Cruz, Laguna, Philippines
Published: May 2024

This paper aimed to support and help people who are experiencing emergencies, mishaps, crimes, vehicle problems, or disasters in Sta. Cruz, Laguna. With this, an Emergency Number Services Rescue Mobile App in Sta. Cruz, Laguna was devised, developed, and evaluated. This app provides different emergency units where people can send emergency message information, GPS location, and direct calls where users or victims encounter an emergency, crime, vehicle problem, or disaster situation. Respondents from Sta. Cruz Laguna using stratified random sampling was utilized. The use of the descriptive method of research was identified in the study. Questionnaires, formal interviews, observation, library resources, and Internet resources were used for data gathering. The emergency application was assessed by the respondents through software evaluation using ISO/IEC 25010:2011, which got an overall weighted mean of 3.79 with an interpretation of “Agree.”
Analysis on the Development of an Android App for the Management of Blood and Organ Donations
Authors:   Department Information Technology, Sreenidhi Institute of Science and Technology, Hyderabad, Telengana, India, Babu Riteesh , Mooga Sushrutha ,   Department Information Technology, Sreenidhi Institute of Science and Technology, Hyderabad, Telengana, India, Sufianuddin Mohd ,   Department Information Technology, Sreenidhi Institute of Science and Technology, Hyderabad, Telengana, India, Iyengar N.Ch. Sriman Narayana ,   Department Information Technology, Sreenidhi Institute of Science and Technology, Hyderabad, Telengana, India
Published: May 2024

Blood and organ donation are considered noble acts of helping mankind. Yet, one major challenge for the involved agencies is finding the exact blood group and needed specific organ at the required time and situation. This paper deals with the development of an Android app aiming to address this problem by tracking the donors and managing the donation process through Cloud computing. The app is designed in such a way that any person who is willing and eligible to donate blood or organs registers their information, which is preserved in the Cloud. It is capable of sending alerts to available donors whenever there’s a patient that needs a particular organ or blood (i.e., with specific details). The utilization of the Cloud for data storage enables the app to be more efficient as compared with the traditional blood and organ donor banks.
Development of an Academic Performance Monitoring System Using Least Squares Regression for Predicting Student Academic Performance Status on Professional Courses
Authors:   College of Computer Studies, University of Antique, Sibalom, Antique, Philippines, Pilarca Cheene Rose , Opiña Defaje Marie ,   College of Computer Studies, University of Antique, Sibalom, Antique, Philippines, Leuterio Jhon Simon ,   College of Computer Studies, University of Antique, Sibalom, Antique, Philippines, Toledo Fretzl Ann ,   College of Computer Studies, University of Antique, Sibalom, Antique, Philippines, Bellones Marjorie ,   College of Computer Studies, University of Antique, Sibalom, Antique, Philippines, Gerona Rexes ,   College of Computer Studies, University of Antique, Sibalom, Antique, Philippines, Sermeno Jason ,   College of Computer Studies, University of Antique, Sibalom, Antique, Philippines
Published: May 2024

This study deals with the development of an academic performance monitoring system using least squares regression to predict a student’s academic performance status on professional courses. The proposed system monitors the student’s academic performance to promote education and achieve learning outcomes. The study aims to design and create a Graphical User Interface (GUI) and its functions, to utilize MATLAB for forecasting and a least squares regression model to show and predict the relationship between two factors, and to evaluate the system’s predicting accuracy using Percentage Forecast Error (PFE) and Mean Absolute Percent Error (MAPE) to compare actual and forecasted data for every semester. The sample size includes 182 students of BS Information Technology, of whom thirteen (13) were successfully chosen using simple random sampling with their GPAs for the purpose of predicting future academic performance.
Rökstenen. Två nytolkningar
Authors: Hultgård Anders
Published: May 2024

This article discusses two recent studies of the Rök rune stone in Sweden (Ralph 2021 and Williams 2021). They follow different lines of interpretations. Ralph views cosmic symbolism as the key to understanding the inscription as a form of riddles in which the text is preserved. The Ragnarök myth presents the background against which Williams elaborates his interpretation. Some runic sequences that show the differences between the scholars are explored in more detail. The aim of the inscription is finally addressed.
Plurale stedsnavn, genusskiftet og forklaringsproblemet
Authors: Haslum Vidar
Published: May 2024

The article discusses an unsolved problem in Nordic name research, namely the reason monosyllabic nouns in neuter take the plural suffix -ar or -ir in the nominative and accusative when they appear as topographical words in uncompounded place-names, which implies a transition to feminine or masculine inflection. Most scholars who have tried to explain this phenomenon have pointed to various analogies at the morpholog-ical level. In this article, it is suggested that such a morphological change can best be explained as a prosodic analogy, as a transition from a monosyllabic to a multisyllabic form is taking place, and this is a prosodic structure that, for a place-name, is much more functional and natural.
Radical Candor: A Review
Authors: Gatlin J. Brad
Published: May 2024

Review of:
Scott, Kim. (2019). Radical Candor: Be a Kick-Ass Boss Without Losing Your Humanity. Fully Revised & Updated Edition. St. Martin’s Press. 297 pages.
Letter from the Editor
Authors: Dulaney Emmett
Published: May 2024

Admittedly, I may be a bit biased, but I think the collection of articles in this issue of the Christian Business Academy Review constitute the best in the eighteen-year history of the journal. There is so much more to being a professor than chalk-and-talk, and the authors whose works were accepted this year provided a wide-ranging look at many aspects of the profession in and beyond the classroom. As you look at what follows, I hope you will agree.
Taking a Step Back—Maslow’s Theory of Motivation: A Christian Critical Perspective
Authors: McCleskey Jim A. , Ruddell Larry
Published: May 2024

This article presents a review of the extant literature concerning Abraham Maslow’s hierarchy of needs theory of motivation as the key component of Maslow’s broader view of motivation. It also includes a synopsis of prior criticisms of the theory. Further, this manuscript presents a Christian critique of Maslow’s motivation theory (specifically his methodology, view of human nature, and hierarchy of needs) so that the reader will gain new insights about motivation from a Christian worldview in contrast to Maslow’s secular model. After analyzing Maslow’s concepts, including self-actualization, peak experience, and the hierarchy of needs using a biblical perspective, we find that Maslow’s theory of human motivation is not supported by Scripture and Maslow is attempting to create a new worldview designed to supplant the traditional Christian worldview.
Social Impact Bonds: Developing a Christian Perspective
Authors: Reeve Kimberly , Michael Hrynuik , William Devine
Published: May 2024

Social Impact Bonds (SIBs), a form of impact investing, were first introduced in 2010 and enable investors to finance innovative projects to create a measurable social benefit. If the project is successful, investors are paid principal plus an agreed-upon return. This paper summarizes the current state of these bonds and concludes with a Christian perspective.
Casting Lots, Gambling, and Artificial Intelligence
Authors: Saunders Kent T. , Locke Larry G.
Published: May 2024

Casting lots was widely practiced in the ancient Near East as a method for making decisions. In the Bible, casting lots was a common method to determine the will of God when allocating land, determining duties, assigning guilt, selecting individuals for responsibility, and other matters. Additionally, there are instances in the Bible where the use of lots can be seen as an unbiased random allocation method or, possibly, an act of gambling. How might this ancient, biblical practice inform the modern use of artificial intelligence in business decisions? The authors begin with an exegesis of casting lots in the Bible, particularly on the question of whether casting lots was a form of gambling. The authors then compare the biblical practice of casting lots with the use of artificial intelligence in business decision-making. The authors argue that neither practice may fairly be defined as “gambling” of the kind forbidden by different Christian traditions. The authors identify a common ethical issue for casting lots and the use of artificial intelligence—the surrender of control over a decision, resulting in the potential to transfer moral responsibility for that decision. While the authors accept that casting lots resulted in a transfer of moral responsibility, they conclude that using artificial intelligence should not similarly allow for a surrender of moral responsibility.
Fraud, Whistleblowing, And Sins Of Omission: A Call To Action
Authors: Bergsma Tim
Published: May 2024

The world economy loses more than $4.4 trillion each year due to fraud. Fraud losses harm economies and societies. This paper specifically addresses the role of non-fraud actors (NFAs) and how their inaction might perpetuate fraud. NFAs are people within close proximity to fraudsters or fraud schemes. Fraud is connected to sin. From a Christian perspective, how might NFA inaction align with sins of omission and, thus, impact shalom? Several implications, in a business context, are offered.
Do Christian CEOs make a difference? Empirical evidence from the S&P 500
Authors: Slater Dan , Holbrook Robert , Xu Joseph
Published: May 2024

Little empirical work has been done on how Christian business leaders make a difference in the firms they lead, particularly in large publicly traded firms. This research draws on upper echelons theory, stewardship research, and scriptural principles, including the life of Joseph from the book Genesis, to argue that Christian CEOs are more likely to act as good stewards of the resources in their charge and in so doing will reap the positive benefits of stewardship for both their firms and themselves. We test our hypotheses on the S&P 500 CEOs and find supporting results suggesting that indeed Christian CEOs make a difference.
An Exploratory Study of International Financial Reporting Standards (IFRS) from a Christian Perspective
Authors: Kang Gerui , Raquel Sylvie , Shin Martha
Published: May 2024

More than 140 international jurisdictions, not including the United States, have standardized the use of International Financial Reporting Standards (IFRS). Secular research on IFRS focuses on its external goods, which has so far generated mixed results. This paper evaluates IFRS from a Christian perspective, looking at its principles-based nature and ability to produce internal goods. Internal goods facilitate the rationality and responsibility of accounting practices that are crucial in achieving the qualitative objective of financial reporting.
Church Finances for Missional Leaders: Best Practices for Faithful Stewardship
Authors: Lockett Jerome
Published: May 2024

Church leaders have a corporate social responsibility (CSR) to their communities and congregations. In this context, CSR is used as a business model to hold church leaders accountable to themselves, stakeholders, and the public. In Church Finances for Missional Leaders: Best Practice for Faithful Stewardship, Bonnie Marden analyzes how churches can steward growth in their congregants and church finances. The author expresses how the practices of church stewardship and financial stewardship must come together and form a continuous joint relationship for the success of the church.
Sural nerve grafts in subacute facial nerve injuries: a report of two cases
Authors: Jeong Jiwon , Chang Yongjoon , Kim Kuylhee , Chung Chul Hoon , Jung Soyeon
Published: May 2024

Because facial nerve injuries affect the quality of life, leaving them untreated can have devastating effects. The number of patients with traumatic and iatrogenic facial nerve paralysis is considerably high. Early detection and prompt treatment during the acute injury phase are crucial, and immediate surgical treatment should be considered when complete facial nerve injury is suspected. Symptom underestimation by patients and clinical misdiagnosis may delay surgical intervention, which may negatively affect outcomes and in some cases, impair the recovery of the injured facial nerve. Here, we report two cases of facial nerve injury that were treated with nerve grafts during the subacute phase. In both cases, subacute facial nerve grafting achieved significant improvements. These cases highlight surgical intervention in the subacute phase using nerve grafts as an appropriate treatment for facial nerve injuries.
An intercontinental comparison of the influence of smoking on the occurrence of nonsyndromic cleft lip and palate: a meta-analysis and systematic review
Authors: Vathulya Madhubari , Singh Neetu , Naithani Manisha , Kessler Peter
Published: May 2024

Background: The influence of smoking on nonsyndromic clefts has been a topic of research for many years. However, few studies have investigated the effect of smoking on causing clefts in different gene pools.Methods: A meta-analysis was conducted of case-control studies related to smoking. Keywords such as “clefts,” “cleft lip,” “cleft palate,” “orofacial cleft,” and “smoking” were used to search the MEDLINE, Embase, and Cochrane databases.Results: In total, 51 articles were reviewed. The RevMan software was utilized for the analysis, and the Mantel-Haenszel method was employed to pool the odds ratios (ORs) and 95% confidence intervals. Although the overall OR, a measure of the association between exposure and outcome, was higher for smokers than for non-smokers, this association was significantly stronger in individuals from Asia and South America (1.73), and lowest in Europe (1.31). Among active and passive smokers in Asia, the OR was approximately 0.93, indicating an equivalent impact from both types of smoking.Conclusion: This analysis indirectly suggests that restriction measures targeting both active and passive smoking are crucial in Asia.
Drift of neural ensembles driven by slow fluctuations of intrinsic excitability
Authors: Delamare Geoffroy , Zaki Yosif , Cai Denise J , Clopath Claudia
Published: May 2024

Representational drift refers to the dynamic nature of neural representations in the brain despite the behavior being seemingly stable. Although drift has been observed in many different brain regions, the mechanisms underlying it are not known. Since intrinsic neural excitability is suggested to play a key role in regulating memory allocation, fluctuations of excitability could bias the reactivation of previously stored memory ensembles and therefore act as a motor for drift. Here, we propose a rate-based plastic recurrent neural network with slow fluctuations of intrinsic excitability. We first show that subsequent reactivations of a neural ensemble can lead to drift of this ensemble. The model predicts that drift is induced by co-activation of previously active neurons along with neurons with high excitability which leads to remodeling of the recurrent weights. Consistent with previous experimental works, the drifting ensemble is informative about its temporal history. Crucially, we show that the gradual nature of the drift is necessary for decoding temporal information from the activity of the ensemble. Finally, we show that the memory is preserved and can be decoded by an output neuron having plastic synapses with the main region.
Nanobody repertoire generated against the spike protein of ancestral SARS-CoV-2 remains efficacious against the rapidly evolving virus
Authors: Ketaren Natalia E , Mast Fred D , Fridy Peter C , Olivier Jean Paul , Sanyal Tanmoy , Sali Andrej , Chait Brian T , Rout Michael P , Aitchison John D
Published: May 2024

To date, all major modes of monoclonal antibody therapy targeting SARS-CoV-2 have lost significant efficacy against the latest circulating variants. As SARS-CoV-2 omicron sublineages account for over 90% of COVID-19 infections, evasion of immune responses generated by vaccination or exposure to previous variants poses a significant challenge. A compelling new therapeutic strategy against SARS-CoV-2 is that of single-domain antibodies, termed nanobodies, which address certain limitations of monoclonal antibodies. Here, we demonstrate that our high-affinity nanobody repertoire, generated against wild-type SARS-CoV-2 spike protein (Mast et al., 2021), remains effective against variants of concern, including omicron BA.4/BA.5; a subset is predicted to counter resistance in emerging XBB and BQ.1.1 sublineages. Furthermore, we reveal the synergistic potential of nanobody cocktails in neutralizing emerging variants. Our study highlights the power of nanobody technology as a versatile therapeutic and diagnostic tool to combat rapidly evolving infectious diseases such as SARS-CoV-2.
Synapsin E-domain is essential for α-synuclein function
Authors: Stavsky Alexandra , Parra-Rivas Leonardo A , Tal Shani , Riba Jen , Madhivanan Kayalvizhi , Roy Subhojit , Gitler Daniel
Published: May 2024

The cytosolic proteins synucleins and synapsins are thought to play cooperative roles in regulating synaptic vesicle (SV) recycling, but mechanistic insight is lacking. Here, we identify the synapsin E-domain as an essential functional binding-partner of α-synuclein (α-syn). Synapsin E-domain allows α-syn functionality, binds to α-syn, and is necessary and sufficient for enabling effects of α-syn at synapses of cultured mouse hippocampal neurons. Together with previous studies implicating the E-domain in clustering SVs, our experiments advocate a cooperative role for these two proteins in maintaining physiologic SV clusters.
Natural genetic variation underlying the negative effect of elevated CO2 on ionome composition in Arabidopsis thaliana
Authors: Cassan Océane , Pimparé Léa-Lou , Mozzanino Timothy , Fizames Cécile , Devidal Sébastien , Roux Fabrice , Milcu Alexandru , Lèbre Sophie , Gojon Alain , Martin Antoine
Published: May 2024

The elevation of atmospheric CO
2
leads to a decline in the plant mineral content, which might pose a significant threat to food security in the coming decades. To date, very few genes have been identified as having a role in the negative effect of elevated CO
2
on plant mineral composition. Yet, several studies have shown a certain degree of diversity in the ionome’s response to elevated CO
2
, associated with genotypic variation. This suggests the existence of genetic factors controlling the effect of CO
2
on ionome composition. However, no large-scale studies have been carried out to date to explore the genetic diversity of the ionome responses to elevated CO
2
. Here, we used six hundred
Arabidopsis thaliana
accessions, representing geographical distributions ranging from worldwide to regional and local environments, to analyze the natural genetic variation underlying the negative effect of elevated CO
2
on the ionome composition in plants. We show that the growth under elevated CO
2
leads to a global and important decrease of the ionome content whatever the geographic distribution of the population. We also observed a high range of genetic diversity in the response of the ionome composition to elevated CO
2
, and we identified sub-populations, showing effects on their ionome ranging from the most pronounced to resilience or even to a benefit in response to elevated CO
2
. Using genome-wide association mapping on the response of each mineral element to elevated CO
2
or on integrative traits, we identified a large set of QTLs and genes associated with the ionome response to elevated CO
2
. Finally, we demonstrate that the function of one of these genes is associated to the negative effect of elevated CO
2
on the plant mineral composition. This resource will contribute to understand the genetic mechanisms underlying the negative effect of elevated CO
2
on plant mineral nutrition, and could help towards the development of crops adapted to a high-CO
2
world.
Identification of nonsense-mediated decay inhibitors that alter the tumor immune landscape
Authors: Cook Ashley L , Sur Surojit , Dobbyn Laura , Watson Evangeline , Cohen Joshua D , Ptak Blair , Lee Bum Seok , Paul Suman , Hsiue Emily , Popoli Maria , Vogelstein Bert , Papadopoulos Nickolas , Bettegowda Chetan , Gabrielson Kathy , Zhou Shibin , Kinzler Kenneth W , Wyhs Nicolas
Published: May 2024

Despite exciting developments in cancer immunotherapy, its broad application is limited by the paucity of targetable antigens on the tumor cell surface. As an intrinsic cellular pathway, nonsense-mediated decay (NMD) conceals neoantigens through the destruction of the RNA products from genes harboring truncating mutations. We developed and conducted a high-throughput screen, based on the ratiometric analysis of transcripts, to identify critical mediators of NMD in human cells. This screen implicated disruption of kinase SMG1’s phosphorylation of UPF1 as a potential disruptor of NMD. This led us to design a novel SMG1 inhibitor, KVS0001, that elevates the expression of transcripts and proteins resulting from human and murine truncating mutations in vitro and murine cells in vivo. Most importantly, KVS0001 concomitantly increased the presentation of immune-targetable human leukocyte antigens (HLA) class I-associated peptides from NMD-downregulated proteins on the surface of human cancer cells. KVS0001 provides new opportunities for studying NMD and the diseases in which NMD plays a role, including cancer and inherited diseases.
Estradiol elicits distinct firing patterns in arcuate nucleus kisspeptin neurons of females through altering ion channel conductances
Authors: Qiu Jian , Voliotis Margaritis , Bosch Martha A. , Li Xiao Feng , Zweifel Larry S. , Tsaneva-Atanasova Krasimira , O’Byrne Kevin T. , Rønnekleiv Oline K. , Kelly Martin J.
Published: May 2024

Hypothalamic kisspeptin (Kiss1) neurons are vital for pubertal development and reproduction. Arcuate nucleus Kiss1 (Kiss1
ARH
) neurons are responsible for the pulsatile release of Gonadotropin-releasing Hormone (GnRH). In females, the behavior of Kiss1
ARH
neurons, expressing Kiss1, Neurokinin B (NKB), and Dynorphin (Dyn), varies throughout the ovarian cycle. Studies indicate that 17β-estradiol (E2) reduces peptide expression but increases
Vglut2
mRNA and glutamate neurotransmission in these neurons, suggesting a shift from peptidergic to glutamatergic signaling. To investigate this shift, we combined transcriptomics, electrophysiology, and mathematical modeling. Our results demonstrate that E2 treatment upregulates the mRNA expression of voltage-activated calcium channels, elevating the whole-cell calcium current and contributing to high-frequency firing. Additionally, E2 treatment decreased the mRNA levels of Canonical Transient Receptor Potential (TPRC) 5 and G protein-coupled K
+
(GIRK) channels. When TRPC5 channels in Kiss1
ARH
neurons were deleted using CRISPR, the slow excitatory postsynaptic potential (sEPSP) was eliminated. Mathematical modeling confirmed the importance of TRPC5 channels for initiating and sustaining synchronous firing, while GIRK channels, activated by Dyn binding to kappa opioid receptors, were responsible for repolarization. Our findings suggest that E2 modifies ionic conductance in Kiss1
ARH
neurons, enabling the transition from high frequency synchronous firing through NKB-driven activation of TRPC5 channels to a short bursting mode facilitating glutamate release. In a low E2 milieu, synchronous firing of Kiss1
ARH
neurons drives pulsatile release of GnRH, while the transition to burst firing with high, preovulatory levels of E2 facilitates the GnRH surge through its glutamatergic synaptic connection to preoptic Kiss1 neurons.
Identification and characterization of the CRK gene family in the wheat genome and analysis of their expression profile in response to high temperature-induced male sterility
Authors: Liu Hongzhan , Li Xiaoyi , Yin Zehui , Hu Junmin , Xie Liuyong , Wu Huanhuan , Han Shuying , Li Bing , Zhang Huifang , Li Chaoqiong , Li Lili , Zhang Fuli , Tan Guangxuan
Published: May 2024

Cysteine-rich receptor-like kinases (CRKs) play many important roles during plant development, including defense responses under both biotic and abiotic stress, reactive oxygen species (ROS) homeostasis, callose deposition and programmed cell death (PCD). However, there are few studies on the involvement of the CRK family in male sterility due to heat stress in wheat (Triticum aestivum L.). In this study, a genome-wide characterization of the CRK family was performed to investigate the structural and functional attributes of the wheat CRKs in anther sterility caused by heat stress. A total of 95 CRK genes were unevenly distributed on 18 chromosomes, with the most genes distributed on chromosome 2B. Paralogous homologous genes with Ka/Ks ratios less than 1 may have undergone strong purifying selection during evolution and are more functionally conserved. The collinearity analysis results of CRK genes showed that wheat and Arabidopsis (A. thaliana), foxtail millet, Brachypodium distachyon (B. distachyon), and rice have three, 12, 15, and 11 pairs of orthologous genes, respectively. In addition, the results of the network interactions of genes and miRNAs showed that five miRNAs were in the hub of the interactions map, namely tae-miR9657b-5p, tae-miR9780, tae-miR9676-5p, tae-miR164, and tae-miR531. Furthermore, qRT-PCR validation of the six TaCRK genes showed that they play key roles in the development of the mononuclear stage anthers, as all six genes were expressed at highly significant levels in heat-stressed male sterile mononuclear stage anthers compared to normal anthers. We hypothesized that the TaCRK gene is significant in the process of high-temperature-induced sterility in wheat based on the combination of anther phenotypes, paraffin sections, and qRT-PCR data. These results improve our understanding of their relationship.
Exploring the Green Valley with the dark energy survey: studying the evolution of galaxies
Authors:   , Gil Toriello Santiago
Published: May 2024

We investigate the properties of galaxies located at the so-called Green Valley, an intermediate region between the blue-cloud of active star- forming galaxies, and the red-sequence of quenched and "dead" galaxies, visible in a color vs stellar mass diagram for galaxies.We utilize data from multiple releases of the Dark Energy Survey (DES), to characterize galaxies based on their physical properties, and to correlate their location in a stellar mass vs color diagram with their morphologies.We selected a sample of high-quality photometric data from the Year 3 re- lease of the Dark Energy Survey, with redshifts ranging from local z ∼ 0, to intermediate z ∼ 1.5, and cleaned it by applying a set of different quality selection criteria. We obtained a number of measurements for the photometric redshifts of the galaxies, by employing different parametric algorithms, to study each evolution separately as a function of distance. With the use of LePHARE, a template fitting code, we measured a set of physical properties of the galaxies that are helpful to study their evo- lution, and to assess the transitional nature of galaxies inside the Green Valley. These are, mainly, the Absolute Magnitude, the Stellar Mass, the Star Formation Rate and the UV Luminosity.We made use of two catalogues for morphological prediction available for the Year 3 release. These catalogues allowed us to better constrain the relation between the morphological structures of galaxies and their evolutionary stage.Results show that combining SED template fitting algorithms with mor- phological analysis allows to constrain the bi-modality distribution even when working with optical surveys, up to redshifts of z = 1.5.This is a first approach on the use of these methods to pave the way more massive and intensive data treatment surveys, like the future LSST survey to be done with the Vera Rubin Telescope.
Dispositivo grupal para desgaste profesional de equipos de profesionales de Atención Primaria de Salud (APS): recomendaciones para un protocolo de autocuidado y cuidado de equipos
Authors:   , Rocha Caro Macarena Pilar
Published: May 2024

La repentina llegada del COVID-19 a nivel mundial, ha significado una crisis sanitaria con grandes consecuencias, donde la capacidad de respuesta para las altas demandas de atención en salud se ha visto limitada, y los profesionales de la salud se encuentran en un lugar central para su enfrentamiento. Anterior a la pandemia, era conocido que los profesionales de la salud se encontraban en alto riesgo en cuanto a su salud mental, debido a varios estresores psicosociales, y debido a la crisis sanitaria, estos riesgos se intensifican, de manera que los trabajadores de salud se encuentran ante un estrés excepcional. En ese sentido, los profesionales de la salud han sido considerados con una alta vulnerabilidad al desgaste profesional -también llamado burnout-, incluso más que antes, y el fenómeno no ha tardado en aparecer entre los profesionales de Atención Primaria de Salud (APS). Ahora bien, los estudios se han centrado mayoritariamente en profesionales de salud en general, y se han caracterizado por implementar estrategias individuales de autocuidado, a pesar de que se puede detectar la necesidad de intervenir igualmente en los niveles grupales y organizacionales, lo cual podría realizarse por medio de la consideración del cuidado de equipo. Es muy escasa la literatura sobre este nivel en particular, al igual que de intervenciones grupales para el desgaste, modalidad de trabajo que parecería tener posibilidades de ser beneficiosa para reducirlo, debido a características propias de la dinámica grupal, además de que el trabajo en el ámbito mencionado conlleva un trabajo en equipo, el cual debe ser considerado. El objetivo general de este estudio es identificar elementos centrales para el desarrollo del desgaste profesional y estrategias favorecedoras de autocuidado y cuidado de equipos con el fin de diseñar recomendaciones para la construcción de un protocolo de dispositivo grupal de intervención y prevención en equipos de profesionales de Atención Primaria de Salud (APS). Los resultados obtenidos se presentan en fases. De la primera fase se presentan resultados descriptivos de la codificación abierta (levantamiento de información). En esta se identificaron dos categorías principales: desgaste profesional y autocuidado. El desgaste profesional se caracteriza por estrés excesivo, dificultad para detectarlo, síntomas como cansancio, desgano y despersonalización, y consecuencias en el rendimiento laboral. Los problemas laborales, alta demanda de pacientes difíciles, mal funcionamiento de la red de derivaciones y problemas personales/familiares contribuyen al desgaste. El autocuidado se refiere a acciones para promover el bienestar del profesional. Se identifican algunas estrategias individuales que incluyen conocer límites, pedir ayuda y terapia.
Isocitrate Dehydrogenase and Alpha Thalassemia/Mental Retardation, X-linked Mutation Status in Human Gliomas at a Tertiary Care Hospital in Southern India: A Cross-sectional Study
Authors: Veeramachaneni Leela Rani , Kate Madhuri Shreesh , Gosain Ratna , Kumar Samson Sujith , Gopikonda Shreya Sri
Published: May 2024

Introduction: The molecular subtyping of human gliomas in the current World Health Organisation (WHO) 2021 classification highlights the diagnostic and prognostic significance of neoplastic entities. This subsequently contributes to a better understanding of immunohistochemistry markers in various glioma patients. Aim: The study aimed to determine the Isocitrate Dehydrogenase (IDH1) gene mutation and Alpha Thalessemia/Mental retardation X-linked (ATRX) mutation in gliomas through immunohistochemistry and clinically categorise them into various subgroups. Materials and Methods: The present cross-sectional study was conducted in the Department of Pathology and Neurosurgery on 50 glioma samples collected from patients who underwent surgery at ESIC Medical College and Super Speciality Hospital in Hyderabad, Telangana, India from June 2018 to June 2023. Histopathological evaluation and Immunohistochemistry (IHC) study for IDH1 and Alpha Thalessemia/Mental retardation X-linked were performed on all patients. Clinical variables such as age, gender, duration of symptoms, and clinical presentation were collected from medical records and tabulated. Results: Total 50 cases of glioma were studied. The expression of IDH1 wild type was observed in 30 (60%) cases, which was more common than IDH1 mutation observed in 20 (40%) cases. The mean age in the study was 41.9 years, with a majority of male patients 33 (66%). IDH1 mutation was commonly observed in diffuse fibrillary astrocytomas (34%) followed by 12% of cases in anaplastic Astrocytomas. Glioblastoma was the most common histopathological diagnosis in 40% of cases, but the observed IDH mutation was least frequent in glioblastomas. Out of the 20 glioblastoma cases, only one tested positive for IDH mutation. In contrast, ATRX loss was predominantly seen in glioblastomas, with three out of the five positive cases. IDH1 mutation was more common in adults than in children, and a female preponderance (60%) was noted. ATRX mutation was observed in only 10% of cases. Conclusion: The IDH1 and ATRX are reliable prognostic markers, and their analysis through immunohistochemistry provides a practical and dependable method for categorising gliomas compared to molecular analysis, thus assisting clinicians in achieving promising treatment outcomes.
Paediatric Clear Cell Sarcoma of Scalp Masquerading as Benign Sebaceous Cyst: A Diagnostic Dilemma
Authors: Paridhi . , Bahadur Shalini , Adhlakha Bhuvan , Kalhan Shivani , Kumar Satendra
Published: May 2024

Clear Cell Sarcoma of Soft Tissue (CCSST) is a rare and aggressive tumour comprising 1% of all soft tissue sarcomas. They tend to recur locally and have a high predilection for regional, as well as, distant metastases. These tumours usually occur in a young age group; however, their presentation in childhood is extremely rare. They are also known as Malignant Melanoma (MM) of soft parts due to similar histological and Immunohistochemical (IHC) features with MM. Distinguishing between them is very difficult morphologically. Both exhibit high lymph node metastases and positive staining for S-100 protein, Melanoma antigen (Melan-A) and Human Melanoma Black-45 (HMB-45). Here, the authors reported an unusual case of an 11-year-old male child who presented with a slowly progressing scalp swelling that was misdiagnosed as a sebaceous cyst radiologically and on Fine Needle Aspiration Cytology (FNAC), which later turned out to be CCSST on histopathology. Unfortunately, the patient was lost to follow-up, but later presented with multiple cutaneous swellings, emphasising the tumour’s aggressive nature. The index case is being reported as an exception to its age of occurrence and unusual presentation that posed a diagnostic dilemma, leading to a delay in treatment. The treatment for CCSST involves wide surgical resection with negative margins, and adjuvant therapy may be considered based on resection outcomes. In conclusion, the present case underscores the diagnostic challenges posed by CCSST, particularly when it occurs in atypical age groups and locations. Timely recognition and differentiation from similar entities, such as MM, are crucial for appropriate management and improved outcomes.
The Effects of Digital Divide on the Educational Rights of Marginalised
Authors: Joseph Anjali Merin , Prakash L T Om
Published: May 2024

The contemporary education system in Kerala, India, has adapted to the online teaching-learning process with the inevitable integration of technological advancements. Within the diverse socioeconomic-politicall and scapes in India, the gapin various forms of capital available for individuals also expands to the realm of digital engagement. The aim of the current study is toanalyse how spatial locations intersect with digital access to education. This paper showcasesmultiple factors responsible for creating the crisis of digital divide among geographically estranged communities. The current study employs a descriptive design and presents its findings through athorough narrative review of the existing literature.
Evaluation of the Digestibility of Diets Containing Soy Okara in Clarias gariepinus (Burchell, 1822) Fries Raised in a Controlled Environment in Benin
Authors: Segnon Constant Bienvenu , Djissou Arnauld Sedjro Martin , Gangbazo Diane Nathalie Sènami Kpogue , Aboh André Boya
Published: May 2024

Aims: To evaluate the digestibility of diets containing soy okara in Clarias gariepinus fries.
Study Design:  Random complete block design.
Place and Duration of Study: Laboratory of Hydrology and Wetland Research, Faculty of Sciences and technics, University of Abomey-calavi, between June 2019 and July 2019.
Methodology: Four diets containing different levels of soy okara (0%, 10%, 20% and 30%) respectively noted T0, T1, T2 and T3 were tested. Twelve 40L tanks were randomly distributed into 04 batches with 03 repetitions for each of the 04 diets. The fries with an initial average weight of 10.47 +/- 2g were fed ad libitum three times a day (8 A.M., 12 P.M., 4 P.M.) for 30 days. Survival rate, cannibalism rate, average daily gain, specific growth rate, weight-length relationship, condition factor, consumption index, ingested protein, protein efficiency coefficient and digestive utilization coefficients were measured.
Results: The specific growth rates (SGR) ranged between 2.25 +/- 0.165 and 2.58 +/- 0.115 with the best rate for the treatment containing 0% soy okara. The consumption index varied from 1.18 +/- 0.009 to 1.41 +/- 0.132 with the best index for the T3 treatment. Furthermore, the mortality rates were 0% for treatments containing 20% and 30% soy okara. The results indicate that it is possible to incorporate up to 30% soybean okara into the diet of Clarias gariepinus fry without hindering their zootechnical performance. The digestive protein utilization coefficients of the diets were calculated and are 95.12; 88.47; 92.21 and 90.37 for diets containing 0%, 10%, 20% and 30% soy okara respectively.
Conclusion: The results demonstrate that among the different diets tested, treatment T2, containing 20% soy okara, proved to be the most favorable in terms of zootechnical performance. These results suggest that T2 treatment can be considered as a promising option for feeding Clarias gariepinus fries.
Transformation of Agriculture in Damoh District of Madhya Pradesh
Authors: Verma Vinay Kumar
Published: May 2024

India has been considered as a land of villages and from very beginning agriculture has been main means of livelihood of the residents of the country specially people living in rural areas. Agriculture plays a vital role in the nation's economy. About two third of the working population earn their living through agriculture and agriculture sector contributes about 26 per cent in the gross domestic production of the country. The present study examines the transformation of the various dimension of the agriculture in the Damoh district of Madhya Pradesh based on secondary data. With the growing pressure of population, demand for land for non-agricultural activities, implementations of rural development programmes and activities, the land use pattern, cropping pattern, irrigational facilities, farming techniques and other allied activities in the study area has transformed during the period 1990 to 2020.  Damoh district is located in the Bundelkhand region of Madhya Pradesh and is part of Sagar division. Total geographical area of the district is 7306 sq.km. out of which 323386 hectares land is available for cultivation with 293599 hectares of irrigated land. The proportion of forest and fallow land has decreased in last two decades while the proportion of net shown area, other uncultivated land, land not available for agriculture and double cropped area has increased during the period. The cropping pattern of the study region, also transformed. The use of modern agricultural implements, fertilizers and pesticides too has increased during 1990-2020.
Evaluation of Nutrient Balance and Nutrition use Efficiency on Red Gram (Cajanus cajan) under Various Foliar Feeding
Authors: G Akshay Kumar , K Udhaya Kumar , D Vanathi , R Samundeshwari , M Silambarasan , J Patricia Kalairasi
Published: May 2024

AIM: To assess the nutrient balance and nutrient use efficiency on red gram.
Place and Duration of Study: A field experiment was carried out during Rabi season 2023-24 at Instruction farm of Karunya Institute of Technology and Sciences, Coimbatore. Experimental          field was silty clay loam in texture with available N (311.0 kg ha-1), P2O5 (15.7 kg ha-1), K2O (185 kg   ha-1).
Statistical Design: Randomized Block Design (RBD).
Methodology: The study consist of 8 treatment and replicated three times T1- 100% RDF + FYM 12.5 t ha-1 + 2% DAP, T2- 100% RDF + FYM 12.5t ha-1 + 2% Urea, T3- 100% RDF + FYM 12.5 t ha-1 + 40 ppm NAA spray, T4- 100% RDF + FYM 12.5 t ha-1 + 10 ppm Salicylic, T5-100% RDF + FYM 12.5 t ha-1 + 75 ppm GA3, T6- 100% RDF + FYM 12.5 t ha-1 + 5 kg TNAU Pulse wonder T7- 100% RDF + FYM 12.5 t ha-1 T8- Control.
Results: Application of 100% RDF along with 12.5 t ha-1 FYM + 5 kg ha-1 TNAU pulse wonder resulted in Maximum nutrient NPK uptake, nutrient availability and agronomic efficiency was observed.
Conclusion: Application of full dose of RDF along with FYM and TNAU pulse wonder reacted better in terms of NPK uptake, nutrient availability and agronomic efficiency when compared to other foliar treatment in the evaluation of nutrient balance and nutrient use efficiency.
Effect of Different Thermal Regimes and Moisture Levels on the Growth Parameters of Wheat (Triticum aestivum L.) Crop Grown under Agro-climatic Conditions of Eastern Uttar Pradesh, India
Authors: Pandey Anushka , Mishra S.R. , Singh A.K. , Mishra A.N. , Singh Alok Kumar , Agrahari Rajesh Kumar
Published: May 2024

A field experiment was carried out at Agrometeorological Research Farm, Acharya Narendra Deva University of Agriculture & Technology, Kumarganj, Ayodhya (U.P.) during rabi season of 2022-23 and 2023-24 to investigate the influence of different thermal regimes and moisture levels on wheat growth parameters, including phenophases occurrence, leaf area index (LAI), plant height, and dry matter accumulation at various stages of crop development.  The experiment comprised twelve treatment combinations and conducted in split plot design and replicated four times. Treatment consisted of three thermal regimes viz. 15th November, 25th November and 5th December with four moisture levels viz, I1 at CRI (crown root initiation) , I2- CRI+tillering, I3- CRI+ jointing and milking, I4- CRI+ jointing +anthesis and dough stage. Results reveal that Plant height (cm), dry matter accumulation (gm-2) and leaf area index increased significantly at all the stages of crop growth . Highest values are recorded with the crop thermal regime on 15th November followed by 25th November. Lowest values of all were recorded in 5th December thermal regime. Among the moisture levels, I4- (CRI+ jointing +anthesis and dough stage) took relatively longer duration for maturirty compared to levels I3, I2 and I1.. These findings underscore the importance of carefully managing both temperature and moisture conditions to optimize wheat growth and development. This research contributes to the broader understanding of crop responses to thermal regimes/date of sowing and provides valuable insights for moisture management strategies aimed at improving crop yield and resilience in the face of changing climate conditions.