bluuebunny/crossref_metadata_2025 huggingface dataset:
ENHANCING STUDENTS’ SPEAKING ABILITY THROUGH COLLABORATIVE LEARNING AT AL MAULIDIYAH ORPHANAGE IN JATIASIH BEKASI
Authors: Supeni Sri , Pribadi Ilham Dhony
Published: September 2021

The aim of this research was to see the improvement of the EFL learners’ speaking ability  through the implementation of  Storytelling Strategy using pictures. This research was also directed to explore the beneficial of collaborative learning for students of Al Maulidiyah Orphanage in Jatiasih Bekasi. The subject consisted of 15 of EFL learners. A Classroom Action Research in two cycles had been conducted within 2 meetings for every cycle. The meetings were focused on the interactivity and communicative ability among learners. The research result showed that the learners’ fulfillment of the storytelling task improved from 40% or 66.7%. It also showed that the learners’ ability in speaking performance improved. The highest improvement was seen from fluency indicator that is from 26.7% to 46.7%. While for the other two indicators namely pronunciation and vocabulary move upward a little. In conclusion, the implementation of Interactive Storytelling Strategy increased the EFL learners’ fulfillment of the storytelling task and their speaking ability
AN ANALYSIS OF FIGURATIVE LANGUAGE AND MORAL VALUE IN ROAR SONG BY KATY PERRY
Authors: Sutrisno Bejo , Lestari Lestari
Published: September 2021

This research is aimed to analyze the figurative languages used in Roar song by Katy Perry. Objectives of the study: (1) to find out the figurative languages used in Roar song by Katy Perry, (2) to find out the meaning of figurative language used in Roar song by Katy Perry, and (3) to find out the moral value messages of the song lyrics. Based on the objective of the study, the researcher uses descriptive qualitative method in collecting the data. From the data analysis, the researcher found out  of figurative language appeared in Roar song by Katy Perry. They are Metaphor, Personification, Simile, Paradox, Irony, Alliteration, Onomatopoeia and Hyperbole. It can be implied that figurative language is always used in song lyrics. In Roar song lyrics, there can find moral value massages that can be learned in by the figurative language shown in this song. That is trusting ourself, never doubt to ourself and believe that we have power to refuse some of bad thins comes to our life such as bullying and toxic relationship.
THE REPRESENTATION OF MEXICAN CULTURE IN DISNEY PIXAR’S MOVIE ENTITLED “COCO”
Authors: Diah Istiwarni , Anisa Siti , Budiarto Budiarto
Published: September 2021

The aims of this research are (1) to find out the meaning of the day of the dead holiday (Día de Los Muertos) based on the movie; (2) to elaborate on the importance of the day of the dead holiday (Día de Los Muertos); and (3) to find out how to deal with a family conflict during the day of the dead holiday (Día de Los Muertos). This study uses a qualitative approach to address research problems as it enables the researcher to perform in-depth studies of a specific phenomenon. The findings or this research are (1) The meaning of the day of the dead holiday (Día de Los Muertos) based on Coco has some indicators such as symbols, heroes, and ritual (2) How the main character deals with his family conflict is that (a) The conflict which comes from the family culture is making the main character to become a rebel. Conflict is highly present in families; however, in general, the presence of conflict is not problematic by itself. (b) parents are making decisions about what they consider is best for all family members.
Faktor Risiko Terjadinya Coronavirus Disease 2019 pada Pasien dengan Komorbid Diabetes Melitus
Authors: Fauzia Nikma Syalsabiela
Published: September 2021

Corona virus disease 2019 (COVID-19) is an infectious disease severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). The clinical scope of Covid-19 varies, from asymptomatic, mild symptoms, to clinical conditions characterized by acute respiratory failure. The most common comorbidities in patients with COVID-19 were hypertension (HTN) (56.2%), followed by diabetes mellitus (DM) (30.1%), and chronic kidney disease (CKD) (17.5%). Several studies suggest that diabetes is one of the main risk factors for COVID-19. Therefore, this literature review aims to determine the risk factors for the occurrence of COVID-19 in patients with diabetes mellitus so that it can be used as a consideration for controlling risk factors and better treatment of COVID-19 patients with comorbidities. The method used in this research is literature review and literature search is carried out through the NCBI, PubMed, and Google Scholar databases. This research involves as many as 24 library sources from 2020-2021. Several studies have shown that diabetes mellitus is a major risk factor for COVID-19. This condition is associated with several macrovascular and microvascular complications that ultimately impact the patient's survival. Diabetes which is a hyperinflammatory condition that can increase susceptibility to COVID-19 with possible mechanisms of chronic inflammation, hypercoagulable state, and activation of the renin-angiotensin-aldosterone system (RAAS) and dysregulation of the sympathetic nervous system. Future research is urgently needed to provide a better understanding of the pathophysiological mechanisms underlying the association between COVID-19 and diabetes, and their clinical management
The Repercussions of Covid-19 on the Stock Market of the Tourism Industry
Authors: Daglis Theodoros , Katsikogianni Maria-Anna
Published: September 2021

The COVID-19 pandemic has already caused important negative consequences on the tourism industry globally. The lockdown measures suspended the tourism activities, and many tourists preferred to abstain from these activities in fear of the virus infection. As a result, investors have abandoned tourism-related companies' stocks, impacting even more the tourism industry. In this article, we examine the impact of COVID-19 on the biggest companies' stocks related to tourism, from the fields of airlines, cruise lines, resorts, hotel groups, travel agents, and other tourism activities (such as car rentals). More precisely, using time series analysis, we test and analyze the effect of the COVID-19 pandemic on these stocks, and we derive the spillover effects through the impulse–response functions from each company to the others. Based on our findings, the tourism-related stocks were affected by COVID-19, as shown by the causality technique, and, moreover, the tourism-related companies are interconnected with each other, transmitting the shock from a specific tourism industry to the others, as shown by the impulse–response functions.
Going . . . Going . . . Going . . . Not Yet Gone! Enhancing Small-scale Festival Survival
Authors: Tkaczynski Aaron , Rundle-Thiele Sharyn , Arli Denni , Gill Chelsea
Published: September 2021

Festival service quality is a precursor to competitive advantage and survival, delivering a positive influence on attendee satisfaction and intentions to repatronize in future. Evidence has been built in large-scale festival settings with mixed constructs and findings reported. Less
is known about small-scale festivals, which operate within more limited human and financial resource constraints. This study aims to confirm the service quality, satisfaction, and behavioral intention relationship for small-scale festivals. Five hundred and twenty-nine respondents attending
four different smallscale festivals participated in an in-person or online self-administered survey. Structural equation modeling confirmed that service quality performance influences behavioral intentions directly and indirectly. Satisfaction and perceived professionalism directly influence
behavioral intentions. Environment directly influences repurchase intentions but not when it is mediated by satisfaction. Focusing on delivery of service quality is essential for small-scale festival survival, given its influence on attendees' satisfaction and behavioral intentions. Ensuring
festivals are delivered in good environments featuring professional staff is the key to ensuring small-scale festival survival.
INFLASI DAN NILAI TUKAR RUPIAH TERHADAP INDEKS SAHAM SYARIAH INDONESIA
Authors: Fuadi Agus
Published: September 2021

Indeks Saham Syariah Indonesia di Indonesia (ISSI) merupakan indikator kinerja pasar saham syariah di Indoneia, perkembangan saham syariah memperlihatkan trend positif. Pertumbuhan ISSI secara fluktuatif dipengaruhi oleh beberapa faktor, diantaranya faktor makro dan mikro ekonomi. Inflasi dan Nilai tukar merupakan faktor makro ekonomi yang mempengaruhi perkembangan saham, dimana ISSI merupakan indeks saham yang dipengaruhi oleh inflasi dan nilai tukar. Penelitian ini bertujuan untuk menganalisis pengaruh Inflasi dan nilai kurs terhadap Indeks Saham Syariah Indonesia. Metode yang digunakan dalam penelitian adalah metode kuantitatif. Perusahaan yang terdapat dalam ISSI menjadi populasi dalam penelitian, dan sampel yang digunakan melalui purposive sampling memperoleh data periode tahun 2014-2018. Analisis yang digunakan melalui uji f (simultan) dan uji t (parsial) menyimpulkan bahwa inflasi dan nilai tukar secara simultan berpengaruh terhadap ISSI. Uji secara parsial menunjukkan bahwa inflasi berpengaruh negatif terhadap ISSI, yang berarti bahwa semakin tinggi inflasi maka ISSI semakin rendah. Sedangkan nilai tukar rupiah tidak memiliki pengaruh terhadap ISSI.
FAKTOR-FAKTOR YANG MEMPENGARUHI SAVING BEHAVIOR GENERASI MILENIAL
Authors: Suryanti Rensi , Setyawan Wisnu , Dwi Nopiana Ulfa
Published: September 2021

Sebagai  Generasi Millenial dalam era perkembangan digital saat ini tentu harus menyadari betul bahwa apa yang dilakukan masa kini akan berdampak pada masa depan dan menabung merupakan salah satu pilihan dalam menjaga kestabilan keuangan untuk jangka pendek maupun jangka panjang. Penelitian ini dilakukan dengan tujuan untuk menganalisis faktor-faktor apa saja yang dapat mempengaruhi saving behavior generasi milenial pada mahasiswa manajemen angkatan 2016 Universitas Pelita Bangsa. Metode analisis data yang digunakan pada penelitian ini adalah metode deskriptif kuantitatif dan data yang digunakan adalah data sekunder dan data primer berupa kuesioner dengan sampel sebanyak 282 mahasiswa. Pengolahan data pada penelitian ini menggunakan program SPPS 26. Hasil dari penelitian ini menunjukan secara parsial financial literacy, self-control, saving motive dan income dapat mempengaruhi saving behavior generasi milenial mahasiswa manajemen angkatan 2016 Universitas Pelita Bangsa, sedangkan secara parsial peer influence tidak berpengaruh signifikan terhadap saving behavior generasi milenial mahasiswa manajemen angkatan 2016 Universitas Pelita Bangsa
PENGARUH KEPEMIMPINAN TRANSFORMASIONAL DAN MANAGEMENT CONTROL SYSTEM SERTA BUDAYA ORGANISASI TERHADAP KINERJA APARATUR PEMERINTAH DAERAH
Authors: Asiah Neng , Sabaruddinsah Sabaruddinsah
Published: September 2021

Penelitian ini bertujuan untuk menguji pegaruh gaya kepemimpinan transformasional, management control system, dan budaya organisasi terhadap kinerja aparatur Organisasi Pemerintah Daerah Kota Bekasi. Metode analisis yang digunakan dalam penelitian ini adalah analisis Regresi Berganda. Data dalam penelitian ini diolah menggunakan software SPSS (Statistical Product and Service Solution) versi 23. Sampel dalam penelitian ini 10 Organisasi Pemerintah Daerah Kota Bekasi. Data yang digunakan dalam penelitian ini diperoleh dari kuesioner yang dibagikan secara langsung kepada responden, kuesioner yang disebarkan dalam penelitian ini berjumlah 60 kuesioner. Hasil penelitian ini menyimpulkan gaya kepemimpinan transformasional tidak berpengaruh signifikan terhadap kinerja organisasi, sedangkan MCS melalui beliefs system berpengaruh positif dan signifikan terhadap kinerja aparatur, MCS melalaui boundary system tidak berpengaruh signifikan terhadap kinerja aparatur, MCS melalui diagnostik system tidak berpengaruh signifikan terhadap kinerja aparatur, MCS melalui interaktif system berpengaruh positif dan signifikan terhadap kinerja aparatur, dan budaya organisasi berpengaruh positif dan signifikan terhadap kinerja aparatur
PENGARUH TINGKAT LIKUIDITAS DAN RENTABILITAS TERHADAP KECUKUPAN MODAL
Authors: Mustopo Agus , Mardiansyah Mardiansyah
Published: September 2021

Penelitian ini bertujuan untuk menganalisis seberapa besar pengaruh likuiditas yang diukur dengan Financing to Deposit Ratio (FDR) dan rentabilitas yang diukur dengan Return On Asset (ROA) terhadap kecukupan modal yang diukur dengan Capital Adequacy Ratio (CAR) pada PT. Bank Panin Syariah Tbk. Data yang digunakan dalam penelitian ini adalah data sekunder yaitu laporan keuangan triwulan PT. Bank Panin Syariah Tbk. periode 2011 – 2015. Teknik analisis data yang digunakan adalah regresi linier berganda, lengkap dengan uji asumsi klasik (normalitas, multikolinieritas, heteroskedasitas, dan autokorelasi). Hipotesis diuji menggunakan uji t dan uji F dengan tingkat signifikansi 5%. Berdasarkan hasil uji parsial menggunakan uji t, diketahui bahwa tingkat likuiditas berpengaruh signifikan positif terhadap kecukupan modal. Sedangkan, tingkat rentabilitas berpengaruh signifikan negatif terhadap kecukupan modal. Secara simultan, likuiditas dan rentabilitas berpengaruh signifikan terhadap kecukupan modal, yaitu sebesar 54.1%, sedangkan sisanya 45.9% dipengaruhi oleh faktor-faktor lain di luar penelitian.
PENGARUH PEMBIAYAAN MURABAHAH TERHADAP KESEJAHTERAAN NASABAH
Authors: Ahmad Ali , Nurrohmah Siti
Published: September 2021

Penelitian ini bertujuan untuk menemukan apakah pembiayaan murabahah berpengaruh pada kesejahteraan nasabah. Hasil penelitian menunjukkan bahwa  pembiayaan murabahah hanya mempengaruhi 0,8% terhadap kesejahteraan nasabah dan 99,2% dipengaruhi dari faktor lain. Pembiayaan murabahah yang diberikan tidak mempengaruhi kesejahteraan nasabah dikarenakan adanya faktor penyalahgunaan akad yaitu nasabah menggunakan pembiayaan murabahah tidak untuk modal usaha melainkan untuk memenuhi kebutuhan sehari-hari seperti biaya sekolah, belanja dapur dan kebutuhan lainya. Penyalahgunaan akad berpengaruh negatif terhadap pembiayaan murabahah yang diberikan. Sehingga pembiayaan murabahah tidak dapat mempengaruhi kesejahteraan nasabah
PRESTASI KERJA : PENILAIAN KERJA KARYAWAN DAN KEPUASAN KERJA
Authors: Rulianti Erina
Published: September 2021

Tujuan penelitian ini yaitu untuk menguji pengaruh penilaian kinerja karyawan  dan kepuasan kerja terhadap prestasi kerja karyawan. Penelitian ini merupakan penelitian deskriptif dengan pendekatan kuantitatif yang dilaksanakan di PT. Mitrapak Eramandiri Cabang Cikarang. Populasi penelitian ini adalah seluruh karyawan PT. Mitrapak Eramandiri Cabang Cikarang yang berjumlah 134 karyawan dengan sampel 57 karyawan. Teknik pengambilan sampel adalah random sampling. Teknik pengumpulan data menggunakan observasi, studi pustaka dan kuisioner. Teknik analisis data yang digunakan adalah uji validitas, uji reliabilitas, analisis linier regresi berganda, koefisien determinasi (r2) dan uji hipotesis. Berdasarkan data analisis, persamaan regresi yang diperoleh adalah sebagai berikut: Y = 0,759 + 0,463 (X1) + 0,274 ( X2). Berdasarkan pengujian hipotesis menggunakan uji t (parsial) bahwa penilaian kinerja karyawan serta kepuasan kerja berpengaruh positif dan signifikan terhadap prestasi kerja karyawan. Hasil uji f (simultan) menunjukan bahwa penilaian kinerja karyawan dan kepuasan kerja berpengaruh positif dan signifikan terhadap prestasi kerja karyawan. Nilai adjust R square sebesar adalah 0,384 atau sebesar 38,4%. Sedangkan sisanya sebesar 61,6% dipengaruhi oleh variabel lain yang tidak dimasukkan atau tidak dibahas dalam penelitian ini.
PENGARUH INFLASI DAN TINGKAT PENGANGGURAN TERHADAP PERTUMBUHAN EKONOMI DI INDONESIA PERIODE 2010 – 2016
Authors: Hartati Nani
Published: September 2021

Makro ekonomi adalah studi tentang kegiatan ekonomi di suatu negara. Indikator ekonomi makro adalah inflasi, pengangguran, dan pertumbuhan ekonomi. Tujuan dari penelitian ini adalah untuk menganalisis faktor-faktor yang mempengaruhi pertumbuhan ekonomi di Indonesia. Faktor-faktor ini meliputi inflasi dan tingkat pengangguran. Penelitian ini menggunakan analisis regresi linier berganda dengan data per semester pada periode 2010 - 2016. Dengan uji parsial inflasi tidak mempengaruhi pertumbuhan ekonomi secara signifikan, sedangkan tingkat pengangguran berpengaruh positif terhadap pertumbuhan ekonomi. Dengan regresi linier berganda simultan terbukti tidak ada pengaruh yang signifikan antara inflasi dan tingkat pengangguran terhadap pertumbuhan ekonomi yang terjadi, hal ini juga ditunjukkan dengan koefisien yang bernilai rendah.
PENGARUH PERSEPSI NASABAH TENTANG PROMOSI DAN KUALITAS PELAYANAN TERHADAP MINAT MENABUNG NASABAH
Authors: Sakum Sakum , Iftia Hidaya
Published: September 2021

Tujuan dari penelitian ini adalah untuk mencari adakah pengaruh antara persepsi nasabah tentang promosi dan kualitas pelayanan secara parsial terhadap minat menabung, di BJB syariah. Tujuan yang kedua adalah untuk mengetahui adakah  pengaruh antara persepsi nasabah tentang promosi dan kualitas pelayanan secara simultan terhadap minat menabung di BJB syariah. Hasil penelitian menunjukkan bahwa ada pengaruh antara persepsi nasabah  tentang promosi dan kualitas pelayanan secara parsial maupun simultan terhadap minat menabung di BJB.  Kualitas pelayanan, dalam penelitian ini, lebih mempengaruhi minat menabung dari pada persepsi nasabah tentang promosi.
JUAL BELI EMAS SECARA TIDAK TUNAI DITINJAU SECARA HUKUM FIKIH
Authors: Kisanda KIsanda Midisen , Handayani Santi
Published: September 2021

Today's gold is only valued as women's jewelry. As an investment platform. Rotting, buying and selling gold too. Increasingly. easy, on reality buy gold already. The growth from cash to non-cash markets is due to the high interest in investment in gold with the exchange of goods as cash as it is, it raises questions. That have developed in communities of clean and illegitimate laws. This research is a type of library literature research. In research researchers use the normative and textual approach, that is, to examine the problem in an existing framework of values based on texts and Islamic law, government regulation and other texts relating to dalarm discussion. In the study it may be concluded that the unlawful sale of gold was two opinions: the first opinion was haram, it was the view of clerical mayonnaise (mahzhab Hanafi, Maliki, Syafi’i and Hambali) and the second opinion was the mubah, this is the opinion of Ibn Taimiyah and Ibn Qayim, as well as contemporary scholars who agree.
IMPLEMENTASI AKAD MURABAHAH PADA PRODUK PEMBIAYAAN MURABAHAH DI KOPERASI SIMPAN PINJAM DAN PEMBIAYAAN SYARIAH BAITUL MAAL WAT TAMWIL FAJAR CABANG BEKASI
Authors: Sakum Sakum
Published: September 2021

In the preparation of this thesis, researchers used qualitative research, the type of research used was library research and field research. Sources of data obtained through primary and secondary data sources, for data collection using two methods, namely: interviews and documentation, for data analysis techniques using 3 methods, namely data reduction, data presentation, and drawing conclusions. This study aims to determine the implementation or practice of the murabahah contract in murabahah financing products at Baitul Maal wat Tamwil Fajar Bekasi branch whether it is in accordance with Islamic law and Fatwa DSN MUI No. 04 / DSN-MUI / IV / 2000 About Murabaha. The result of this research is that in the practice of the murabahah contract at KSPPS BMT Fajar has implemented it according to the SOP and in accordance with Islamic law and fatwa DSN MUI No. 04 / DSN-MUI / IV / 2000 About Murabaha. Based on the results of the study, it can be concluded that the implementation of the murabahah contract on murabahah financing products at KSPPS BMT Fajar Bekasi branch is in accordance with Islamic law and Fatwa DSN MUI No. 04 / DSN-MUI / IV / 2000 About Murabaha. This is based on the results of the analysis of interviews with members who apply for murabahah financing.
PENGARUH PENGELUARAN DANA PROGRAM KEMITRAAN USAHA DAN RELAWAN TERHADAP PENGHIMPUNAN DANA ZAKAT (Studi Lembaga Amil Zakat Baitulmaalku Karawang Periode 2017 - 2019)
Authors: Hamdan Muhammad Hamdan 'Ainulyaqin , Lutin Hendro
Published: September 2021

The very positive potential of zakat in Indonesia triggers competition betweem many amil zakat institutions to gain muzakki‟s trust. In zakat management institutions the activities of collecting (fundraising) zakat funds are very important for amil zakat institutions to cary out institutional activities. This study aims to analyze the effect of business and volunteer partnership programs on the collectionbof zakat funds. Volunteer and business partnership program as an independent variable and zakat fund collection as the dependent variable. The object of research at the Baitulmaalku Karawang amil zakat intitute.

The research method uses quantitative methods of data collection with secondary data in the form of financial reports. The subject of this research is the Baitulmaalku Karawang amil zakat institution. The number of samples is 36, the analysis method used is multiple linear regression analysis, classical assumption test, and hypothesis testing. The analysis results obtained partially, the business partnership program has a value of 4,214 and a significance value of 0,00 and volunteeers have a t value of 1,616 and a significance value of 1,16. simultaneously get the F value count 122,528 and a significance value of 0,00. The business partnership program has a positive and significant effect on the collection of zakat fund. Whilw volnteers do not have a positive and significant effect on the collection of zakat funds. Simultaneously partnership of business and volunteers affects the collection of zakat funds.
PENGARUH KOMPETENSI DAN STRESS KERJA TERHADAP KINERJA KARYAWAN PT BUSANA UTAMA TEXTILE (DEPARTEMEN SEWING)
Authors: Hasyim Wachid , Rokhmatin Isnaini
Published: September 2021

Human Resources is one of the most important factors in a company. It is not easy to find professional human resources to be a problem today. This is due to several factors including the level of competence and work stress that can affect employee performance. This study aims to analyze the competence and work stress on the performance of the employees of PT Busana Utama Tekstil (Sewing Department) Pekalongan. This type of research is quantitative. The population in this study were employees of PT Busana Utama Textile (Sewing Department) Pekalongan. The data were collected using saturated sampling sent to 60 respondents. The data techniques in this study were questionnaires and documentation with Multiple Linear Regression Analysis, with the help of SPSS 21 for windows software.

 The results showed that competence and work stress together have a significant effect on employee performance, indicated by the value of F count = 3.656> F table = 2.54 with a significance level of 0.032 <0.05. Likewise, the partial test (t test) for the competency variable (X1) obtained the value of t = 2.177> t table = 2,000 with a significance level of 0.034 <0.05, but there is a variable Job Stress (X2) which has no significant effect on employee performance by obtaining t count = 0.624 < t table = 2,000 with a significance level of 0.535 > 0.05. Meanwhile, the correlation between competence and work stress on employee performance obtained R2 value of 0.083 or 8.3% while the remaining 91.7% was carried out by other factors outside of the study. This the criteria for companies to be able to improve performance by making improvements continuously. so that it can have a positive impact on the company.
Isolated metastatic lung disease: review of prognostic factors for surgical treatment
Authors: Dubinina Tatiana , Levchenko E.V. , Mikhnin A.E. , Mamontov O.Y.
Published: September 2021

Currently, the surgical method remains leading in the combined treatment of pulmonary metastases. This review provides modern information about prognostic criteria for surgical treatment (primary metastasectomy and repeated resections and chemoperfusion of the lung (ILuP)) of isolated metastatic lung lesions with various primary tumors. It is concluded that knowledge of the influence of various factors on overall survival will create the basis for drawing up an accurate algorithm in determining indications for surgical treatment of patients with metastatic lung disease.
Prognostic possibilities of molecular genetic testing for assessing the risk of recurrence of papillary thyroid cancer in children
Authors: Sergiiko S , Lukianov Sergei , Titov Sergey , Veriaskina Iuliia , Romanchishen Anatolii , Gostimskii Aleksandr , Kazachkov Evgenii , Pasternak Ilona
Published: September 2021

The assessment of aggressiveness and risk of death in papillary thyroid cancer in children is currently based on clinical criteria. To ensure a more accurate risk stratification, new criteria and various molecular genetic markers are constantly being sought. The article studied the dependence of the clinical and pathological manifestations of papillary thyroid cancer in children on the level of expression of various microRNAs and the presence of the BRAF mutation. It was found that the BRAF mutation was present in 20.4% of cases, while the dependence of the clinical behavior of cancer on the BRAF mutation was not established. Of the 14 microRNAs studied, statistical differences were obtained for oncogenic miR-146b, -221, -31, and oncosuppressive miR-144, which correlated with signs such as extrathyroid tumor growth, multi-focus, and metastasis to the neck lymph nodes.
Breast cancer in patients after augmentation with implants
Authors: Khodorovich Olga , Solodkii Vladimir , Kalinina-Masri Alena , Sarkisian Karen , Sherstneva Tatiana , Kleshneva Viktoriia , Kanakhina Liia
Published: September 2021

Relevance. Currently, there is no definite answer to the question of the cause of breast cancer, since it is a systemic and multifactorial disease. Given that the number of aesthetic operations on the mammary glands using endoprostheses only increases every year, new cases of detection of malignant diseases do not decrease. Some researchers are beginning to speak out about the possible connection of augmentation mammoplasty in the anamnesis with the subsequent occurrence of breast cancer due to inadequate clinical and instrumental examination and ignoring some of its components (for example, the mammographic examination).
Introduction. Taking into account the analysis of the literature and the presented clinical examples, the possible reasons for the connection of augmentation mammoplasty in the anamnesis with the subsequent detection of a malignant neoplasm are analyzed.
Materials and methods. We analyzed domestic and foreign literature and described two clinical examples with authentic documentation based on the results of the examination and treatment. The article describes in detail the schemes of drug treatment and descriptions of the results of morphological examination of the surgical material. The types and results of surgical treatment with reliable photos are also presented.
Results. Given the complexity of the diagnostic stage in patients with breast endoprosthesis in the described clinical examples, family history collected in sufficient detail, cytogenetic studies conducted, we should talk about the likely underdiagnosis during preventive examinations.
Conclusion. The multifactorial and systematic nature of such a disease as breast cancer suggests that perhaps an intensive increase in the detectability of the above-mentioned against the background of previously performed aesthetic surgery would be the simplest solution to the problem. In this category of patients, anamnesis should be collected in more detail and carefully, and the entire complex of clinical and instrumental examinations, including mammography, magnetic resonance and ultrasound examinations, should be performed in order to fully diagnose and develop further patient management tactics.
The development of quality of life psychosocial model in cancer patients after lower limb amputation
Authors: Shchelkova Olga Yu. , Iakovleva Maria , Usmanova Ekaterina , Sofronov Denis , Rylnikov Pavel , Sarzhevskaya Yana , Salkov Alexandr
Published: September 2021

The general trend of humanization in medicine in recent decades, along with the biopsychosocial approach to health and illness, has put on the agenda the problem of patients’ quality of life, which resulted in numerous researches. The relevancy of this issue and the need of its investigation is substantiated in the present article on the ground of the analysis of modern literature and the work experience in the oncoorthopedic clinic; the results of the first stage of quality of life study and number of factors determining it in patients with bone and soft tissues tumors in lower extremities who underwent amputation are presented. Such a study should be comprehensive and should include an analysis of the objective functional capabilities and clinical indicators of patients, the subjective assessment of the main aspects of quality of life after amputation, as well as the psychological, social, demographic characteristics of patients. This implies the development of a theoretical model including the components of analysis in their integrated unity and interaction, as well as mathematical and empirical verification of the model. The development of quality of life psychosocial model can help to create scientifically based programs of individualized psychological assistance and social rehabilitation of cancer patients undergoing amputation of lower limb. The authors –doctors and clinical psychologists of the N.N. Blokhin Cancer Research Center and the St. Petersburg State University– put forward a research program in order to develop such a model, as well as present the first results of its implementation.
Features of pain syndrome in patients with bone metastasis
Authors: Khmelevskii Evgenii , Bychkova Natalia
Published: September 2021

Purpose. The purpose of the current study was the search for evaluation criterion for the radiosensitivity of bone metastases of various origins.
Materials and methods. The first part of the study presents a modern classification of pain, method of its evaluation, mechanisms and features of metastatic bone pain. The radiobiological patterns of pain relief in low-dose anti-inflammatory radiation therapy were also considered. The analysis of these features testifies in favor of the antitumor mechanism of pain relief in high-dose irradiation. To identify the relationship between pain and other clinical symptoms, 810 cases of bone metastases of various localization and morphology were analyzed.
Results. The severity of pain directly correlates with gender, lesion length and little affected by the presence of pathological fracture. The intensity of pain does not depend on the primary tumor and bone metastases localization and does not correlate with the presence of neurological deficit.
Conclusion. Completeness and persistence of the analgesic effect may reflect the real radiosensitivity of bone metastases, but taking into account the patient's gender and lesion length in the irradiated area.
А case of breast cancer in pms2 mutation carrier
Authors: Vasiliev Aleksei , Ianus Grigorii , Suspitsyn Evgenii , Iyevleva Aglaia , Sokolova (Strelkova) Tatiana , Bizin Ilya , Sokolenko Anna , Preobrazhenskaya Elena , Ni Valeriia , Laidus Tatiana , Chuynyshena Svetlana , Gorgul Iulii , Aleksakhina Svetlana , Mikhetko Andrei , Imianitov Evgenii
Published: September 2021

Breast cancer (BC) is not a typical manifestation of Lynch syndrome. The existence and extent of excessive breast cancer risk in carriers of pathogenic mutations in the Lynch syndrome-associated genes (MLH1, MSH2, MSH6, PMS2) remains an open question. In addition, it is known that some of the breast neoplasms in patients with this syndrome are causally linked to the hereditary mutation, and some arise completely independently of the hereditary defect in the gene of the DNA mismatch repair system. In the case of accidental detection of such germline mutations in breast cancer patients, a thorough differential diagnosis between these categories of tumors is required, and the result of it is actionable, requiring changes in the management. This is a report of a case of breast cancer that arose in a carrier of a pathogenic mutation in the PMS2 gene, which was an accidental finding. The description of molecular genetic diagnostics is given: the microsatellite markers assessment and the detection of «loss of heterozygosity» allowed to classify the neoplasm in a category of cases that developed without any causal link to the patient's Lynch syndrome.
Procedures for Acquisition of Land Ownership
Authors: OMELCHUK Oleh , CHUDYK-BILOUSOVA Nadiia , TARANENKO Liudmyla
Published: September 2021

It is established that the right of ownership of land is a set of powers of individual entities in relation to land plots or the right to them, enshrined in the norms of law, taking into account the restrictions established by law. The subjects of land relations are characterized depending on the form of land ownership. It is proposed to understand the procedure of granting land ownership as the activity of interested persons or state bodies of the relevant levels and other entities, which is aimed at establishing the right of the relevant entity to a specific plot. It is established that the procedure for acquiring a plot of land by a person is clearly defined and includes several methods defined by law. Procedures for acquiring land ownership by a natural or legal person are analysed, depending on the methods defined by land and civil legislation. It is proposed to introduce only an electronic form of land auctions. It is established that an additional condition for the acquisition of property rights in market conditions is the positive results of the inspection for compliance with the requirements established by the land legislation of the potential purchaser or owner of the agricultural land. The inspection procedure needs to be regulated by the relevant by-law to comply with the requirements of the adopted amendments to the land legislation. The most acceptable model for the introduction of the land market is a moderately limited agricultural land market, which restricts access to purchase by foreigners and legal entities. The expediency of ensuring the proper settlement of relations when concluding agreements on the transfer of ownership of land in market conditions is substantiated. The procedure for acquiring the right of ownership of land is the process of acquiring a person, the right of ownership of land for possession, use and disposal on the terms and in the manner prescribed by law as a result of the decision of the authorized body. The classification of procedures for acquiring land ownership is carried out.
Transfer of Property of the Deceased to the Ownership of Public Legal Entities
Authors: BORYSLAVSKA Maryna
Published: September 2021

Public law entities such as the state and the territorial community have been found to have general grounds for acquiring ownership of property left after the death of an individual in the following cases: they are indicated in the will as an heir; the heir waives the share due to him/her in favor of the state or territorial community. In addition, each of these entities has grounds for acquiring (inheriting) the property of the deceased, relating exclusively to him-her. Thus, a territorial community becomes the successor of the property of the deceased person, in respect of whom there were no heirs after being recognized by court as fictitious in the manner prescribed by law. The property of the deceased may pass to the state in two other cases: the inheritance was opened before July 1, 2003, but was not accepted by any of the heirs (according to article 555 of the Civil Code of Ukraine of 1963); The state of Ukraine is the heir to international treaties. It is established that the latter ground is not mentioned in the Civil Code of Ukraine, which is assessed as a gap in legislation. A detailed analysis of all the mentioned grounds for the acquisition of property of the deceased is carried out. The conclusion is confirmed that the transition to a territorial community of fizzy inheritance is not inheritance. The possibility of submitting an application to the court for recognition of the inheritance as a fictitious body of the prosecutor’s office in the interests of the territorial community, which usually occurs with the inaction of the local government, is justified. The following features of the recognition of inheritance as a fictitious property are highlighted: 1) the rules of law that fix the transition of the hereditary mass to the favor of the territorial community are mandatory in nature, that is, the local government body in its interests is obliged to apply to the court; 2) only one participant in civil legal relations — the territorial community acquires property that has not been inherited; 3) there is no limitation (maximum period) on the moment for appeal to the court; 4) to recognize the inheritance as fictitious, a person needs an appropriate court decision that has entered into legal force. It is proposed to supplement the Civil Code of Ukraine with article 12771 on the transfer to the state of inheritance discovered abroad.
Small-scale Turbulent Motion of the Plasma in a Solar Filament as the Precursor of Eruption
Authors: Seki Daikichi , Otsuji Kenichi , Isobe Hiroaki , Del Zanna Giulio , Ishii Takako T. , Sakaue Takahito , Ichimoto Kiyoshi , Shibata Kazunari
Published: September 2021

A filament, a dense cool plasma supported by the magnetic fields in the solar corona, often becomes unstable and erupts. It is empirically known that the filament often demonstrates some activations such as a turbulent motion prior to eruption. In our previous study, we analyzed the Doppler velocity of an Hα filament and found that the standard deviation of the line-of-sight velocity distribution in a filament, which indicates the increasing amplitude of the small-scale motions, increased prior to the onset of the eruption. Here, we present a further analysis on this filament eruption, which initiated approximately at 03:40 UT on 2016 November 5 in the vicinity of NOAA Active Region 12605. It includes a coronal line observation and the extrapolation of the surrounding magnetic fields. We found that both the spatially averaged microturbulence inside the filament and the nearby coronal line emission increased 6 and 10 hr prior to eruption, respectively. In this event, we did not find any significant changes in the global potential field configuration preceding the eruption for the past 2 days, which indicates that there is a case in which it is difficult to predict the eruption only by tracking the extrapolated global magnetic fields. In terms of space weather prediction, our result on the turbulent motions in a filament could be used as the useful precursor of a filament eruption.
Adjunctive Application of Systemic Antibiotics in Non-surgical Aggressive Periodontitis Treatment: Clinical and Microbiological Findings
Authors: Milinkovic Iva , Mijailovic Iva , Markovic Aleksa , Janjic Bojan , Nikolic Nadja , Milasin Jelena , Milicic Biljana , Aleksic Zoran , Vasovic Dina
Published: September 2021

BACKGROUND: Aggressive periodontitis (AgP) is associated with an extensive and rapid destruction of periodontal tissues. Unpredictable treatment outcomes of the disease are consequences of various cross-linked factors. Antimicrobial adjunctive treatment is routinely used as a part of non-surgical periodontal treatment (NSPT) of AgP.
AIM: Therefore, the aim of this study was to compare the effects of active periodontal treatment (APT) combined with systemic antibiotics with mechanical debridement alone, in patients with generalized AgP (GAgP).
METHODS: Two groups, consisting of 10 participants each, were randomly formed. Both groups were clinically and microbiologically tested and monitored for 3 months. Test group received APT with antimicrobial supplementation (amoxicillin and metronidazole [AMX-MET]). Patients from the control group were treated by APT only. Clinical and microbiological parameters were recorded at baseline and 3 months following the NSPT. Clinical measurements involved probing depth, clinical attachment level, bleeding on probing, and plaque index. Samples of subgingival crevicular fluid were analyzed by qualitative polymerase chain reaction.
RESULTS: Significant improvement of all clinical parameters was observed 3 months following the NSPT (p < 0.05), but significant difference between groups was not found (p > 0.05). Periodontal pathogens’ detection between baseline and 3 months follow-up was also not statistically significant in both examined groups (p > 0.05).
CONCLUSION: Similarity of results obtained in both treatment groups underlined the key role of APT in the treatment of AgP. The AMX-MET supplementation did not improve clinical and microbiological outcomes, when compared to APT alone. Longer follow-up period, with larger sample, could provide a more comprehensive insight into this issue.
La santé publique comme objet sociologique
Authors: Gelly Maud , Mariette Audrey , Pitti Laure
Published: September 2021

Tout en maniant des paradigmes différents d’analyse, les trois sociologues que nous avons interviewé·e·s dans le cadre de ce dossier témoignent des enjeux de l’autonomie d’une recherche sociologique qui se donne la santé – et notamment la santé publique – pour objet. Le premier entretien permet de revenir sur l’histoire d’un courant de sociologie critique à travers la trajectoire de Patrice Pinell. Formé à la médecine puis à la biochimie dans les années 1960 avant de se convertir à la sociologie et de diriger, pendant plus de dix ans, une unité de recherches psychanalytiques et sociologiques en santé publique au sein de l’Inserm, ce dernier fait de la santé et de la médecine des objets de sociologie générale et critique, en développant une analyse socio-historique du champ médical. Le second entretien interroge les enjeux des recherches sociologiques sur la santé dans des mondes professionnels et des institutions de santé publique, à partir de deux trajectoires professionnelles et scientifiques : celle de Cécile Fournier, chercheuse à l’Institut de recherche et documentation en économie de la santé (Irdes), et celle de Gabriel Girard, chargé de recherche à l’Institut national de la santé et de la recherche médicale (Inserm) après un parcours dans le domaine de la santé publique au Québec.
Écrire la question écrite
Authors: Kerléo Jean-François
Published: September 2021

Les questions écrites résultent d’un jeu complexe d’écriture : l’élu peut être l’auteur officiel et unique qui cherche à obtenir de précieuses informations dans le cadre de ses fonctions ou bien le relais des aspirations d’un auteur officieux qui se cache derrière un « prête-nom » parlementaire. Dans toutes ces hypothèses, les questions écrites servent d’outil d’information à destination, soit de l’élu et de la société civile, soit du Gouvernement qui se trouve interpellé par des acteurs innommés. Ainsi la réponse importe-t-elle moins que la question qui sert à faire pression sur le pouvoir exécutif et à l’informer de l’état d’une partie de l’opinion publique. Se posent ainsi de nombreuses questions déontologiques découlant de l’instrumentalisation des questions écrites par les lobbies et de l’opacité des relations entre eux et les parlementaires.
Les questions écrites à la chambre des Communes et au Bundestag : un élément important de l’activité quotidienne des députés aux effets politiques limités
Authors: de Nantois Christophe
Published: September 2021

Les questions écrites au Royaume-Uni et en Allemagne sont d’ordinaire classées parmi les instruments du contrôle parlementaire. Il n’est pas du tout certain que cet objectif de contrôle soit atteint ni même recherché. Certes les questions écrites sont très utilisées puisque plusieurs milliers de questions sont posées chaque année, mais les questions écrites cherchent bien plus souvent à répondre à des points techniques et limités, à mettre leur auteur en lumière, qu’à contrôler véritablement l’action gouvernementale. Cette technique unique est cependant un mécanisme démocratique à la fois utile et discret car elle permet aux citoyens d’obtenir indirectement des réponses à des questions pour lesquelles la réponse tarde à venir par les voies classiques. Cette procédure met alors en valeur le député qui s’en est saisi, ce qui, de fait, renvoie alors à une procédure aux accents clientélistes qui nuit à la défense des intérêts collectifs que le Parlement est censé protéger.
La normativité des réponses ministérielles
Authors: Noël Johanna
Published: September 2021

Le sujet de la normativité des réponses des ministres aux questions écrites des parlementaires n’est pas nouveau. Pourtant, il fait partie des sujets sur lesquels la doctrine a peu écrit. Un consensus existe entre les acteurs juridiques et politiques : elles sont dépourvues de toute valeur normative. En dehors des réponses ministérielles dans le domaine fiscal (art. L. 80 A du Livre des procédures fiscales), elles ne sont ni opposables à l’administration ni justiciables devant le juge. En 2018, a été introduit l’article L. 312-3 du code des relations entre le public et l’administration, qui prévoit sous condition l’opposabilité des réponses ministérielles. Celui-ci, en réalité, ne change que peu de choses à la normativité des réponses ministérielles. Les réponses ne sont pourtant pas « rien » ; elles ont un rôle pratique à ne pas négliger, celui d’orienter les conduites. C’est cette fonction qui oblige à discuter à nouveau de leur nature en convoquant d’autres concepts comme celui de force normative ou encore de performativité des actes de langage.
La responsabilité de l’État est engagée en cas d’absence de mise en œuvre de mesures efficaces pour lutter contre les « rodéos urbains »
Authors: Burg Marc
Published: September 2021

La répression des rodéos urbains ou motorisés, parce qu’ils ne constituent pas des troubles de voisinage, relève de la seule compétence de l’État dans les communes où la police est étatisée. Il appartient alors au préfet de prendre toutes les mesures requises pour garantir la tranquillité publique. La carence dans l’action des services étatiques constitue une faute susceptible d’engager la responsabilité de l’État, pour faute simple. En revanche, la police municipale n’est pas dépourvue de tous moyens pour réprimer les rodéos motorisés, notamment du fait de ses compétences au titre du code de la route et de ses compétences en matière de police judiciaire. La coopération entre les forces de police étatiques et municipales semble être la meilleure solution pour répondre au mieux à ce trouble important à l’ordre public.
La comparaison « au-delà » des systèmes de droit : l’exemple de la protection de l’environnement
Authors: Moccia Luigi
Published: September 2021

Il y a deux thèses, distinctes mais étroitement liées l’une à l’autre, que nous essayons d’argumenter dans cet article. La première est que la mondialisation, économique et technologique, mais aussi sociale et culturelle, se reflète sur le plan juridique, remettant ainsi en cause le droit comparé pour repenser et réaffirmer sa propre vocation d’étude critique et ouverte, en tant que « science de contexte », qui se pose au niveau théorique comme une manière autoréflexive de connaître le droit. La deuxième thèse est qu’il existe des sujets, parmi lesquels l’environnement est peut-être le plus emblématique, qui sont comme des fondements de comparaison, dans le sens qu’ils représentent des paradigmes d’un nouveau statut méthodologique et épistémologique de l’approche comparative en tant que moyen d’étude et de recherche juridiques. Cette approche, au lieu de concevoir le monde à travers le droit à la manière de la classification (taxinomie) des systèmes juridiques mondiaux, elle cherche plutôt à concevoir le droit à travers le monde, dans sa dimension « globale », à la fois spatiale et territoriale, commune et particulière, universelle et relative, selon le point de vue et ses implications.