bluuebunny/crossref_metadata_2025 huggingface dataset:
RESTRIÇÃO ALIMENTAR: DIFERENÇAS ENTRE PERTENCER OU NÃO A CURSOS DA SAÚDE E AS VIVÊNCIAS DURANTE A PANDEMIA DA COVID-19
Authors: Amaro Rolfsen Ana Laura , Sumico de Lima Uyeno Jordão Karyne , Moraes César
Published: October 2023

O conjunto de características que diferencia pessoas que praticam maior restrição alimentar e vivenciam repercussões prejudiciais à saúde em função da prática, demanda maior elucidação. Conhecer essas características em resposta a situações de estresse extremo como o que ocorrera na pandemia da COVID-19 é aspecto pertinente visto que conhecer a influências destas situações sobre o comportamento alimentar pode auxiliar na construção de habilidades para melhorar a alimentação da população. Neste contexto, o presente estudo teve por objetivo investigar a relação entre características de universitárias e vivências na pandemia sobre os componentes da restrição alimentar: descontrole alimentar, restrição cognitiva e comer emocional. Para isso, foi realizado um desenho transversal com utilização de survey online, com obtenção de respostas de noventa e três mulheres universitárias ao Three Factor Eating Questionnaire com 21 itens (TFEQ-21), questionário que mede a restrição alimentar segundo os fatores descontrole alimentar, restrição cognitiva e comer emocional. Os resultados foram comparados a “pertencer ou não à área da saúde”, “perceber ou não impactos na saúde física e emocional na pandemia”, “perceber ou não mudanças no corpo na pandemia”, Índice de Massa Corporal e dados sociodemográficos.  Os dados foram analisados por análise de variâncias com covariável (ANCOVA) e correlação de pearson. Não houve diferença significativa entre pertencer ou não a área da saúde (descontrole alimentar: F=0,60, p=0,44; restrição cognitiva: F=1,31, p=0,25; comer emocional: F=0,37, p=0,56) ou perceber os impactos físicos e mentais (descontrole alimentar: F=0,14, p=0,7; restrição cognitiva: F=1,79 p=0,18; comer emocional: F=2,66, p=0,11) sobre as variáveis de interesse. Mas houve maior pontuação significativa para restrição cognitiva entre aqueles que perceberam mudanças positivas no corpo durante a pandemia em relação aos que não perceberam (F=3,84, p=0,025). A maior pontuação de restrição cognitiva entre os que relacionaram mudanças positivas no corpo pode se relacionar ao maior grau de rigidez que profissionais da saúde (boa parte da amostra) comumente se impõe em relação a alimentação e forma corporal, o que pode ter se agravado na pandemia. Essa rigidez merece observação já que pode se relacionar com repercussões negativas para a saúde.
Relationship-Oriented Recovery System for Youth (RORSY): Clinical Protocol for Transition-Age Youth with Opioid Use Disorders
Authors:   Partnership To End Addiction, Hogue Aaron
Published: October 2023

This article introduces the Relationship-Oriented Recovery System for Youth (RORSY) protocol, which is designed to increase uptake of Medications for Opioid Use Disorder (MOUD) and related services among adolescents and young adults. Youth exhibit alarmingly poor rates of MOUD initiation and adherence, OUD services involvement and long-term recovery success.
Skrining Fitokimia dan Profil Kromatografi Lapis Tipis (KLT) Tumbuhan Antimalaria Asal Indonesia
Authors: Arifuddin Muhammad , Bone Mahfuzun
Published: October 2023

Phytochemical screening tests have been carried out to detect secondary metabolites in several plants, namely Brotowali stem (Tinospora crispa), Jambu Biji leaves (Psidium guajava), Manggis rind (Garcinia mangostana), Pare fruit (Momordica charantia), Pepaya leaves (Carica papaya), Pulai sari stem bark (Alstonia scholaris), Sirsak leaves (Annona muricata). The test results obtained the state that each sample of the plant contains secondary metabolites which have the potential as antimalarial compounds.
Formulasi dan Evaluasi Hidrogel Mukoadhesif Metronidazole Menggunakan Kombinasi Kitosan dan Natrium Karboksimetilselulosa
Authors: Fahrurroji Andhi , Wijianto Bambang , Styawan Agus
Published: October 2023

Antibiotik metronidazole merupakan suatu antibiotik yang sering digunakan pada pengobatan infeksi, salah satu penggunaannya adalah dalam pengobati infeksi Helicobacter pylori. Antibiotik ini memiliki kelarutan yang relatif tinggi pada kondisi asam yaitu 30,6 mg/mL pada pH 1, sebagai upaya untuk mengoptimalkan kelarutan tersebut maka dilakukan pengembangan sediaan yang bertahan lama pada kondisi lambung sediaan tersebut adalah dalam bentuk hidrogel mukoadhesif yang dapat mempertahankan waktu tinggal di lambung lebih lama sehingga terapi infeksi H.pylori lebih optimal. Tujuan dari penelitian ini adalah melihat pengaruh penggunaan kombinasi polimer kitosan dan natrium karboksimetilselulosa yang dapat mengontrol pelepasan metronidazole secara in vitro dalam sediaan hidrogel. Metode yang digunakan untuk memprediksi formula tersebut adalah menggunakan desain faktorial yang selanjutnya diambil formula optimumnya. Rancangan formula awal untuk memprediksi formula optimum terdiri dari 4 formula dengan perbandingan polimer kitosan dan natrium karboksimetilselulosa berturut-turut 0,5:1,5; 1,0:1,5; 0,5:3,0; dan 1,0:3,0. Hasil pengamatan  menunjukkan formula optimum dengan perbandingan polimer kitosan dan natrium karboksimetilselulosa sebesar 1,0% (kitosan) dan 3,0% (natrium karboksimetilselulosa), dengan respon untuk kemampuan mengembang  sebesar 96,95%; kekuatan mukoadhesif sebesar 0,1911 N/cm2; dengan pelepasan obat sebesar  67,457 % dan mekanisme pelepasan obat mengikuti sistem difusi Fick. Berdasarkan uji independent sampel t-test pada program SPSS 22 menjelaskan bahwa formula hasil observasi tidak berbeda siginifikan dengan hasil prediksi (p-value>0,05).
Pasien Laki-Laki Usia 29 Tahun dengan Urolithiasis Di Klinik Saintifikasi Jamu: Studi Kasus
Authors: Nisa Ulfatun , Widhi A Peristiwa R. , Zulkarnain Zuraida , Fitriani Ulfa , Wijayanti Enggar
Published: October 2023

Setiap individu memiliki resiko Sekitar 5-10% terkena batu saluran kemih (BSK) sepanjang hidupnya. Angka kekambuhan penyakit BSK sekitar 50 % setelah 5 tahun dan 80-90% setelah 10 tahun. Selain pengaturan pola makan yang bisa menjadi solusi dalam menurunkan resiko terjadinya batu saluran kemih, herbal atau fitoterapi dapat menjadi alternatif pilihan dalam pengobatan penyakit batu saluran kemih. Tujuan studi kasus ini untuk memberikan informasi pasien dengan batu saluran kemih yang berobat dengan jamu di klinik saintifikasi jamu hortus medicus Tawangmangu. Batu saluran kemih sebesar 7 mm keluar melalui kencing setelah minum rebusan jamu yang terdiri dari daun tempuyung, daun kumis kucing, daun keji beling, alang-alang, temulawak, kunyit dan meniran.
Assessment of bacteria exposure in vitro activity to 1st, 2nd, 3rd and 4th generation-cephalosporins and Comparison effects
Authors: K. Salim Dunia , A. Altif Ibraheem , H. Abdulwahab Marwa
Published: October 2023

The emergence and spread of resistance to cephalosporin generations are threateningto create species resistant to all currently available agents. Recently, we have seen thedevelopment and spread of bacteria carrying metallo-betalactamase genes that areresistant to cephalosporins (and all beta-lactams). This study was designed tocomparison the effects of first, second, third and fourth- generation-cephalosporin ondifferent bacterial species, which include: Escherichia coli, Enterobacter cloacae,proteus mirabilis, Klebsiella pneumonia, Pseudomonas aeruginosa, Streptococcuspneumonia and Staphylococcus aureus. 11 cephalpsporins antibiotics were used inthis study, which include: cefalexin, cefazolin, cephalothin, cefuroxime, cefoxitin,cefaclor, ceftibuten, cefotexime, ceftazidime, cefpirome and cefepime. kirby bauermethod was used to detect the activity of these antibiotics in vitro. Results showedthat cefpirome and cefepime antibiotics belonging to 4th generation cephalosporin,exhibit antibacterial spectrum effective, except Str. pneumonia and K. pneumonia.Some cases, 1st generation cephalosporin exhibit more antibacterial spectrum effectivethan other cephalosporin generation. In conclusion. This study indicated thatinsignificant influence among four cephalosporins generation on different bacterialspecies. Although, cephalosporins antibiotics have variant activity against differentbacterial species, but the resistant development among bacteria become the publicproblem during the past 2 decades.
Synthesis & spectroscopic studies of some Oxazepeines & Benzooxazepine derivatives
Authors: J.Mohammed Moayed , Kh. Ahmed Ahmed , T.Abachi Faris
Published: October 2023

The present work includes synthesis, characterization and investigation of a newcompounds of [1,3] oxazepines and [1,3] benzooxxazepine which were prepared frompyrimidine -2- thione Schiff-bases (compounds 5-12) with maleic or phthalicanhydride. The chemical structures of the synthesized oxazepine products(compounds 13- 28) were confirmed on the bases of physical & spectroscopic FTIR,NMR (1H & 13CMR) data.
Mixed Fidelity Shape Models for Efficient Small Body Gravity Modeling
Authors: Pedros-Faura Anivid , McMahon Jay W.
Published: October 2023

The polyhedral gravity model is the de facto standard for computing the gravity field near the surface of small bodies due to their irregular shapes. However, the computational load to compute the gravitational acceleration can increase significantly for high-resolution shape models. In this work, an algorithm for creating mixed-resolution shapes is developed with the goal of getting similar accuracy in the gravitational acceleration while reducing the computational cost. This method is tested for full integration into low-altitude trajectory simulations. The results show that blended models can provide comparable accuracy while improving the computation performance. Additionally, this approach does not require any fitting or estimation process as it only involves creating shape model connections, which is done in a deterministic manner. Test cases with asteroids Bennu and Itokawa demonstrate that the errors in the gravitational accelerations computed with the hybrid models are comparable to expected uncertainties from unknown heterogeneous mass distributions. For precomputed hybrid shape model strategies, we see savings in computational time on the order of 50% compared to using the high-resolution shape model, while getting much lower propagation errors than using only a low-resolution model alone.
Dual-Function Cloak of Edge Target in Metamaterial Plate with Active Intelligent Control
Authors: Jiang Jing-Wei , Wang Yi-Ze
Published: October 2023

Wave invisibility has attracted great attention because of its significant influences on mechanical, acoustic, and many other fields, and it has a great potential application to practical engineering. In this work, a dual-function cloak is proposed in which there is an edge object with an intelligent control system in an elastic wave metamaterial plate. Based on the image and scattering cancellation methods, the scattering mode coefficients are derived. The effects of material and structural parameters on dynamic stress concentration and scattering amplitude are investigated. The cloaking configuration consists of concentric layers of piezoelectric (lead–zirconate–titanate [PZT]) patches, which are connected with the intelligent control system. The theoretical and experiment results show that the dual-function cloak can effectively reduce the dynamic stress concentration and scattering amplitude. Compared to the range from 100 to 450 Hz for the original structure without a control system, the effective frequency range of the intelligent cloak can be extended from 100 to 500 Hz. The present design with both strength enhancement and invisibility of the edge target is expected to provide new ideas for the development of mechanical metamaterials and novel structures.
Aerodynamic Characterization of a Fan-Array Wind Generator
Authors: Li Songqi , Liu Yutong , Jiang Zhutao , Hu Gang , Noack Bernd R. , Raps Franz
Published: October 2023

Experimental assessment of safe and precise flight control algorithms for unmanned aerial vehicles under gusty wind conditions requires the capability to generate a large range of velocity profiles. In this study, we employ a small fan-array wind generator that can generate flows with large spatial and temporal variabilities. We perform a thorough aerodynamic characterization, operating the fans uniformly from low to maximum levels. Particle image velocimetry and hot-wire measurements indicate a jetlike flow with a nearly uniform core, which monotonously contracts in the streamwise direction and the surrounding, growing unsteady shear layers. These complex dynamics result in a limited region with a desired flow profile and turbulence level. The experimental results shed light on the flow generated by a full-scale fan-array wind generator, and they indicate the need for further improvements via properly designed add-ons and dedicated control algorithms.
Cross-Field Structured Adaptive Mesh Using Medial Axis Flow Feature Extraction
Authors: Deng Siqiang , Wang Yibin , Qin Ning
Published: October 2023

A method to generate feature-aligned anisotropic structured meshes automatically is presented for high resolution of two-dimensional complicated flow features such as normal and oblique shock waves, shock reflection, shock/shock interaction, and shock/boundary-layer interaction. The method starts from extraction of dominant flow features to be treated alongside geometric entities. This is followed by automatic generation of multiblock structured meshes of the flow domain using a cross-field based method so that the flow feature entities are embedded along with the geometries. The cross-field method allows for the automatic blocking so that anisotropic quadrilateral meshes generation and adaptation to resolve flow features can be carried out. The resulting mesh possesses high element quality for orthogonality and high resolution of the flow features, suitable for the shock capturing methods and higher-order reconstruction schemes. The method is demonstrated through a number of aerodynamic flow test cases with discussion on its efficiency, accuracy, and robustness.
Vibration and Heat Transfer Study on Elastic-Tube Heat Exchange with Curved Baffle
Authors: Xiwang Qie , Jiadong Ji , Feiyang Li , Xu Deng , Jianxin Zhou
Published: October 2023

A heat exchanger with a curved baffle for an elastic-tube bundle (ETB) is designed to effectively improve the performance based on a common ETB heat exchanger, and this paper systematically studies its vibration and heat transfer characteristics under different inlet velocity and structural parameters. The results indicate that the ETB vibration characteristics increase significantly with an increasing velocity, and the average amplitude of the ETB at [Formula: see text] is 4.51 times higher than that at [Formula: see text]. Similarly, the heat transfer performance subsequently decreases, but the average heat transfer coefficient of the ETB is significantly increased with the increase of the inlet velocity. When the long axis increases from 45 to 75 mm, the vibration intensity of the ETB decreases sharply, and the [Formula: see text] direction and the total vibration [Formula: see text] decrease by 43.4 and 51.5%, respectively. At the same time, the heat transfer coefficient of the ETB and its growth rate decrease by 3.9 and 45.6%. Additionally, the baffle curvature has little impact on the vibration and heat transfer performance. The difference between the average heat transfer coefficient and the total vibration amplitude of the ETB for different baffle curvatures is less than 5%.
RECONSTRUCTIVE PRACTICES AS A RESOURCE FOR THE DEVELOPMENT OF ORIENTATION TO THE FATHERLAND AS A VALUE
Authors:   Orenburg State University, Orenburg, Russia, Zhuikov S.О.
Published: October 2023

The development of modern society is characterized by complex international political instability, crisis phenomena in the socio-economic development of the state, spiritual imbalance in society and insufficient attention of young people to spiritual values. In such a situation, Russia is making every effort to preserve traditional values and historical truth. The most important task of the state and Russian education is to strengthen educational work on the development of orientation to the Fatherland as a value. Today it is important to prevent the loss of interest in the national history, culture and traditions. The Fatherland belongs to the absolute universal values and is one of the main means of educating youth patriotism. Currently, patriotic education is a priority in the country’s educational policy. It is impossible to build a strong Russia without love for the Fatherland, for native places, for the native language. Without respect for one’s own history, traditions and customs of one’s people, it is impossible to raise decent citizens. One of the modern innovative resources for the development of orientation to the Fatherland as a value is historical reconstruction. Reconstructive practices, as a democratic, creative and interactive form of patriotic education, have very extensive axiological possibilities in pedagogy. “Live” historical authentic representations are aimed at understanding the military episodes of the history of the state, contribute to the education of genuine feelings of patriotism and citizenship, arouse pride in the ancestors, deep respect for the history of the Fatherland. On the example of historical reconstruction “Afghanistan: 9 years, 1 month and 19 days” actualized the importance of historical reconstruction as an effective way of knowing the past and a resource for the development of orientation to the Fatherland as a value.
DEVELOPMENT OF PROFESSIONAL READINESS OF MASTER’S STUDENTS TO WORK WITH GIFTED CHILDREN
Authors:   Orenburg State Pedagogical University, Orenburg, Russia, Tavstukha O.G. , Miheeva E.V. ,   Orenburg State Pedagogical University, Orenburg, Russia, Moiseeva A.N. ,   Orenburg State Pedagogical University, Orenburg, Russia
Published: October 2023

A qualitative leap in the development of new technologies has led to the need of society for people who are able both to solve new problems in an unconventional way and to bring new content to all spheres of life. Therefore, today an important direction in state policy in the field of education is connected with the development and support of children with increased educational needs and abilities, which constitutes the potential of the country. To identify such children at the earliest stage, to promote the development of their talents is the task of modern education. The primary role in this process is played by teachers working with children. It depends on them whether the child will be able to develop his/her abilities or not. In modern psychological and pedagogical research works, it is noted that only a teacher with general and special knowledge, certain personal qualities of character can work effectively with such a category of students as gifted children. All this demanded the timely and qualitative preparation of students of correspondence courses to work with gifted children in educational institutions. Readiness to work with gifted children is directly related to the readiness of teachers to implement the educational process in accordance with the requirements of modern state educational policy, taking into account the needs, capabilities, desires and abilities of students, to develop and implement program and methodological documentation, to carry out scientific and methodological work and dissemination of advanced pedagogical experience, to the development and implementation of pedagogical innovations in the educational process. The purpose of our experimental work was connected with the practical implementation of the organizational and pedagogical conditions for the development of professional readiness of students of correspondence courses (teachers of additional education) to work with gifted children.
METHODOLOGICAL ASPECTS OF TEACHING MATHEMATICS USING INFORMATION AND END-TO-END TECHNOLOGIES
Authors:   Orenburg state university, Orenburg, Russia, Usova L.B. , Shakirova D.U. ,   Orenburg State University, Orenburg, Russia
Published: October 2023

Digital transformation affects all aspects of educational and professional activities. An urgent task of digital transformation of education is access to digital and end-to-end technologies. Modern digital and end-to-end technologies provide an innovative approach to learning, put forward new digital tools for the development of the university, promote the exchange of accumulated knowledge and experience. The use of digital technologies in modern education has become an affordable and reliable tool that contributes to improving the daily work of high-tech industries and service companies. This article is devoted to the review of new opportunities of digital transformation in education. Attention is paid to the role of information and end-to-end technologies, digital tools in teaching mathematical disciplines. The necessity of including these technologies in the educational process in connection with the demand for their application in modern professional activity is substantiated. On the basis of information and digital end-to-end technologies, the authors updated the main blocks of the work program of the discipline “Discrete Mathematics and mathematical Logic” In the fund of evaluation tools, practice-oriented tasks were developed. Taking into account: analysis and integration of scientific and methodological literature, internet resources, experience of scientific and pedagogical activity, the authors have improved and tested the methodology for the formation of digital competencies of students of the 02.03.02 Fundamental Informatics and Information Technology training direction.
Être Et Chair Chez Merleau-Ponty
Authors: Saint Aubert Emmanuel de
Published: October 2023

D’après ses propres termes, Merleau-Ponty appelle de ses vœux une « philosophie de la chair » et une « nouvelle ontologie ». Il ne s’agit pas là de projets différents, mais bien d’un seul et même geste. Ce qui ne signifie pas pour autant que les deux expressions se recouvrent parfaitement, encore moins que la chair et l’être forment un seul et même concept. L’objet de cet article est justement d’éclairer chez Merleau-Ponty les sens et enjeux de la chair, de l’être, ainsi que leurs rapports. Avant de rappeler la genèse critique de sa conception de la chair, il faut revenir au terme lui-même et à ses significations dans la langue française, puis dissiper certains contresens encore courants sur le sens merleau-pontien de la chair. Autant de préalables nécessaires avant d’interroger le statut de l’ontologie chez Merleau-Ponty, l’originalité de sa conception de l’être, puis d’aborder quelques traits saillants des relations que le philosophe esquisse entre être et chair.
Gestar sensibilidades em diálogo: tarefa para a fenomenologia da percepção na era digital
Authors: Fabri Marcelo
Published: October 2023

A era digital está promovendo a ruína da vida teórica. O artigo investiga se é possível preservar uma tal vida, beneficiando-se das conquistas da fenomenologia da percepção. Mas isso nos conduz a um desafio que muitos consideram destinado ao fracasso. Trata-se de gestar (formar) sensibilidades em diálogo, subjetividades impactadas pelo acontecimento do aprender e do ensinar. Daí a pergunta: haveria ainda sentido em se falar em corpos grávidos de futuro, subjetividades capazes de reativar e reanimar o convívio intersubjetivo a partir do qual reencontramos nossa participação na cultura e na história? Aposta-se na resposta de que somos ainda capazes de afirmar a nossa liberdade, reivindicando uma responsabilidade pelo futuro. Responsabilidade que tem seu ponto de partida numa fenomenologia da percepção.
Descartes, Husserl e a epoché como fundamento existencial
Authors: Dantas Caio Lívio Sulpino
Published: October 2023

O presente artigo tem por objetivo analisar a influência do pensamento de René Descartes sobre o conceito de epoché de Edmund Husserl. Trataremos do conceito de epoché, portanto, realçando o papel do cogito em suas implicações fenomenológicas. Husserl condiciona a epoché à discussão sobre o caráter constituinte da consciência, portanto ao intuicionismo e às remessas intencionais, opondo-se à interpretação objetivista e físico-naturalista da consciência. Afirma, desta feita, a partir de Descartes, uma naturalidade operacional primeira à naturalidade das ciências modernas. Ao abster-se do ego afirmativo por meio da dúvida sistemática (o cogito), Husserl promoverá uma renovação da relação entre consciência e sentido, seguindo-se de uma renovação da noção de consciência a partir da defesa de uma existência correlata ao mundo. O que se fez possível graças à renovação da subjetividade alcançada na epoché fenomenológico-transcendental.
A encarnação muda tudo: a gênese da filosofia da carne no pensamento de Merleau-Ponty
Authors: Ribeiro Júnior Nilo
Published: October 2023

Essa investigação visa apresentar em linhas gerais a gênese da filosofia da carne com base na obra do filósofo francês Merleau-Ponty. Não se pode negar o fato de que a filosofia de nosso autor esteja a receber um novo fôlego na contemporaneidade graças tanto à publicação como à recepção de seus escritos Inéditos referentes aos cursos ministrados na fase intermediária de seu pensamento (1950), lançados na França no início dessa década. Sem sombra de dúvida, esses escritos, em consonância com os que o antecedem como a Fenomenologia da Percepção (1945), bem como os posteriores, oferecem ao leitor elementos novos para a matização da compreensão da carnalidade em função de sua ontologia da negatividade desenvolvida na obra da maturidade O visível e o invisível (1960). Ao ater-se à questão da gênese da filosofia da carne pretende-se igualmente salientar que o pensamento do autor focado no mote de que a encarnação muda tudo, permite reinscrever as questões da linguagem, da cultura, da ética, da subjetividade, da alteridade etc., em um outro espaço existencial e ontológico a ponto de se poder evadir da tendência à abstração do Logos teorético ou até mesmo dos limites da fenomenologia transcendental de certa forma ainda latentes em algumas correntes filosóficas hodiernas.
A percepção e o artista: uma perspectiva antropológica da fenomenologia de Merleau-Ponty
Authors: Silva Patricia Mara Rodrigues
Published: October 2023

O objetivo do presente artigo é apresentar o modo particular com que Merleau-Ponty trabalha o primado da percepção para a fenomenologia, tomando por base as reflexões levantadas por ele no texto A dúvida de Cézanne. Nosso texto se faz em três tópicos; no primeiro discorre-se rapidamente acerca das concepções de corpo e espírito; e em seguida parte-se para a análise de como a pintura de Paul Cézanne nos é apresentada pelo autor como um modo particular de pesquisa fenomenológica; para que, então, no terceiro tópico, seja esclarecida a importância da percepção para se pensar uma nova concepção de racionalidade humana que funcione fora dos impasses das dicotomias, corpo e espírito, sensibilidade e inteligência, e que, para tanto, será preciso reaprender a vincular-se ao mundo sensível e reconhecer definitivamente a percepção como um modo de conhecimento. Só assim será possível viver nossa animalidade humana em toda sua identidade relacional.
Merleau-Ponty e Wittgenstein escapando da oposição entre ciência e fé apoiada no absolutismo alienante de um radicalismo obtuso
Authors: Parreiras Mônica
Published: October 2023

O presente artigo tem por objetivo abordar a conflituosa relação entre ciência e fé, com vistas a mostrar a impossibilidade de invalidar tanto o campo da ciência quanto o campo da fé. Com isso, defende-se a tese de que invalidar significa assumir uma postura absolutista que tem como principal característica o assujeitamento alienante derivado de um radicalismo obtuso, ou seja, os posicionamentos radicais tornam os indivíduos alienados por ficarem assujeitados em um fechamento. Para tal, toma-se por base as elaborações de Maurice Merleau-Ponty principalmente na sua tese de doutoramento Phénoménologie de la Perception (1945). Ao longo do artigo, recolhe-se algumas notas de outras obras suas com o intuito de ilustrar uma postura legitimadora quanto à importância de abertura ao inacabamento, concernente à ciência, bem como, à religião. Por fim, versa-se sobre a teorização de Ludwig Wittgenstein em Lectures e Conversations on Aesthetics, Psychology and Religious Belief (1967), abordando sua concepção fideísta da crença em Deus não pelo viés das crenças factuais, racionais e/ou empíricas, mas vistas por ele, como uma maneira de ver o mundo e se posicionar nele. O paralelo entre os referidos autores serve para corroborar a tese de que é inexequível pensar a ciência e a fé por um viés essencialmente cartesiano, mas, sobretudo, assinalar a impossibilidade de explicar cientificamente a fé, ou anular sua importância nas trilhas do humano, além de reconhecer o valor da ciência para a evolução da humanidade.
Os registros de pré-natal sob a perspectiva dos enfermeiros de unidades básicas de saúde
Authors: Cardoso Ana Cláudia Paiva , Feitosa Bruno Raphael da Silva , Corrêa Mayra Loreanne Nascimento , Santos Matheus Lopes dos , Correa Aldalice Tocantins , Santana Pablo Palmerim , Silva Marlucilena Pinheiro da , Mata Nely Dayse Santos da , Nemer Camila Rodrigues Barbosa
Published: October 2023

Objetivo: Analisar os registros de pré-natal sob a perspectiva dos enfermeiros das Unidades Básicas de Saúde (UBS’s) em uma capital da Amazônia Legal. Métodos: Trata-se de um estudo descritivo, qualitativo, no qual foram visitadas as unidades básicas do município. Para coleta de dados foi utilizada a entrevista semiestruturada realizada com os enfermeiros. Foram entrevistados 59 enfermeiros, de 19 unidades básicas de saúde. A análise dos dados foi realizada através da análise categorial de Bardin. Resultados: Pode-se inferir categorias que analisam as ferramentas utilizadas para o registro das consultas, a falta de uniformidade desses registros, entender a importância do prontuário como documento legal tanto para a paciente quanto para o profissional e a falta de conhecimento dos profissionais a respeito do armazenamento desses arquivos. Conclusão: Ficaram evidenciados a necessidade de padronização do preenchimento dos prontuários e elaboração de estratégias para atender as necessidades das gestantes de forma mais efetiva, e a vulnerabilidade do arquivamento de prontuários nas UBSs. As falhas nos registros de informações prejudicam a construção de indicadores e, consequentemente, prejudicam a avaliação do pré-natal.
Apicificação de incisivos centrais superiores avulsionados
Authors: Silva Maria Eduarda Sampaio Freitas , Cavalcante Kaline Bereniz Marinho de Araújo , Perciano Isabelle Costa de Almeida , Lessa Samara Verçosa
Published: October 2023

Objetivo: Relatar o caso de trauma dentolalveolar em um paciente do gênero masculino de 9 anos, com avulsão dos incisivos centrais superiores e o sucesso no reimplante dentário dos mesmos. Detalhamento do caso: Durante a consulta emergencial o responsável relatou que a criança havia sofrido um trauma e procurou o dentista, cerca de 60 minutos após o acidente. Foi realizado reimplante e esplintagem dos dentes 11 e 21 e após a intervenção cirúrgica, foi feita uma contenção semirigida com fio ortodôntico. Após a realização dos exames clínicos e radiográficos, o tratamento proposto foi apicificação para os dentes reimplantados, foi utilizado medicação intracanal com hidróxido de cálcio, com troca a cada sessenta dias. Após 2 meses da conclusão do tratamento endodôntico do elemento 11, observou-se aspecto de normalidade nos tecidos dentário e gengival no elemento 21, e foi visto que o mesmo apresentava reabsorção radicular por substituição. Considerações finais: Após esse período, consideramos que, mesmo com a presença de reabsorção, os dentes avulsionados puderam ser mantidos em função, ajudando no restabelecimento estético, funcional e equilíbrio psicológico do paciente.
Dificuldades para atuar na rede de enfrentamento à violência contra a mulher no sul da Bahia
Authors: Moreira Michelle Araújo , Dias Marcella Bonifácio Lelles , Pereira Maryana Orrico , Almeida Lilian Conceição Guimarães de , Marques Patrícia Figueiredo , Araújo Junior José Carlos de , Carneiro Yolanda Aguiar
Published: October 2023

Objetivo: Analisar as dificuldades elencadas por profissionais para o trabalho na Rede de Enfrentamento à Violência contra a Mulher no Sul da Bahia. Métodos: Estudo qualitativo, descritivo e exploratório, realizado com 12 profissionais que atuam em instituições da Rede de Enfrentamento à Violência contra a Mulher. Os dados foram coletados por meio de entrevista semiestruturada, através de gravação por aparelho digital, entre novembro de 2022 e fevereiro de 2023 e analisados por meio da técnica de conteúdo temática proposta por Bardin. Resultados: As dificuldades elencadas pelos profissionais estão relacionadas à insuficiência de recursos, baixa qualificação profissional, alta demanda social, a morosidade no atendimento e pouca articulação na rede. Conclusão: Há necessidade de maior captação de recursos financeiros, materiais e humanos, melhorias na articulação dos serviços e na capacitação profissional além de apoio contínuo dos gestores nacionais, estaduais e municipais para ampliação dos serviços de atendimento à mulher vítima de violência.
Photodynamic interstitial stereotactic therapy for recurrent malignant glioma
Authors: Rafaelian Artem , Martynov Boris , Chemodakova Kseniia , Martynov Roman , Kholyavin Andrey , Papayan Garry , Svistov Dmitry
Published: October 2023

Objectives

Stereotactic photodynamic therapy (sPDT) using 5-aminolaevulinic acid (5-ALA) as a cytotoxic photosensitizer may be a potentially prospective treatment option for malignant gliomas.

Material and Methods

We analyzed data from 10 patients with recurrent malignant gliomas of the brain who were treated with sPDT at the Department of Neurosurgery of the Military-Medical Academy S. M. Kirov, from 2020 to November 2021. Three patients were treated with sPDT again after 3, 7, and 15 months due to relapse.

Results

The median age of the patients was 55.5 years, range was 30–60 years, there were six men and four women. At the time of sPDT, 7 (70%) patients with recurrent tumors were diagnosed with glioblastomas (WHO grade IV), and 3 (30%) with anaplastic astrocytomas (WHO grade III). Tumors were without IDH mutation in 7 (70%) patients; MGMT gene expression status was evaluated in tumors in 9 (90%) patients. A 1p/19q co-deletion was not detected in any of the patients. The median tumor volume was 5.85 cm3 (min. 3.2 cm3, max. 22.5 cm3). We have found that the median recurrence-free period after sPDT in patients with anaplastic astrocytomas and glioblastomas was 435 and 195 days, respectively.

Conclusion

This result allows to consider sPDT as one of the perspective methods of treatment of patients with recurrent gliomas of high malignancy in cases when repeated open surgical intervention has high risks of new neurological deficit.
Losing vigilance in diagnosing pulmonary alveolar microlithiasis: A report on four cases
Authors: Van Luong Hoang , Anh Lam Viet , Nguyen Pham Thanh
Published: October 2023

Pulmonary alveolar microlithiasis (PAM) is a rare chronic lung disease characterized by calcium and phosphate deposition in the alveolar lumen throughout the parenchyma of both lungs, with predominance in the middle and lower lung fields. It is caused by mutations in the recessive gene, SLC34A2, on the autosomal chromosome. In this article, we characterize four cases of PAM and analyze the loss of diagnostic vigilance in two of them. Patients came to medical facilities with clinical manifestations such as cough, shortness of breath, chest pain, and fatigue. The initial diagnosis was unclear in two cases because the X-ray film’s quality was not good enough and the medical staff had little experience in clinical and chest X-ray interpretations for PAM. The definitive diagnosis was based on a combination of high-resolution computed tomography (CT) and bronchoalveolar lavage fluid testing. In addition, chest X-ray and high-resolution CT enable the assessment of the stage, progression, and severity of the disease. There is currently no specific treatment for PAM other than lung transplantation.
Congenital afibrinogenemia presenting with cellulitis in the lower back: A case report
Authors: Shamanur Latha Gowda , M Swathi , Gopan Swetha , Mandal Shibendra
Published: October 2023

Afibrinogenemia is a rare inherited bleeding disorder characterized by the complete absence of fibrinogen, a clotting protein essential for normal blood coagulation. We present a case of a 13-year-old girl diagnosed with afibrinogenemia at the age of 1 month, now admitted due to cellulitis in the lower back. Here, we have examined how to diagnose a case of these uncommon conditions and emphasized the management and treatment strategy for such a case.
Bio-degradation of Azo dye by the Bacteria isolated from Textile Industry Effulent of Solapur district
Authors: Lingappa K. , Sindhe Ananda , Sneha Horti , Begum Nabeela , Ratkal Mahesh
Published: October 2023

Nowadays, water pollution is one of the major problems which the world is facing. Many factors are responsible for water pollution, among the various reasons, one of the major reason is the dyes released from the textile industry, as they contains numerous numbers of chemicals and heavy metals which affect the water and its habitats which are responsible for health problems in humans like cancer and other diseases in humans. In order to control this, elimination of azo dyes which is being released from the textile industries is necessary. In order to eliminate this, biological approach has been applied. In the present investigation, we isolated around 5 different bacterial strains from the textile effluents collected from industrial area of Solapur, Maharashtra. India in which the strain KL (SN) was found to decolorize the malachite green upto 40mg/1000ml with a 70.39% decolourization at a temperature of 280C and at a pH of 7 at 120 rpm for 4 days which was found to be highest than other strains. Further the strain KL (SN) was found to have 99.9% similarity with Tistrella mobilis.
Synthesis and characterization of Guargum Mandelic acid resin and its applications in industrial wastewater treatment
Authors: Sankhla Manisha , Singh A.V.
Published: October 2023

Presently, micro pollutants which occur in water resources worldwide are the main problematic issues causing hazardous effect on environment and harming human life. Polymeric resins are the effective adsorbents, which have properties like static chemical properties, high porosity and specific adsorbent sites. The new resin Guargum Mandelic Acid Resin (GMA), has been synthesized which is toxic free substance for the treatment of industrial waste water. Guargum Mandelic Acid Resin (GMA) has been used for the adsorption of heavy metal ions like Lead (Pb2+), Copper (Cu2+), Iron (Fe2+), Chromium (Cr²+), Zinc (Zn+²) etc. by batch and column method. The GMA resin was characterized by FTIR and SEM. In laboratory, experiments were performed at different pH range, concentration and time of contact.
Phytochemical profiling, antioxidant and antimicrobial activity of aerial parts (stem bark and aerial roots) of Ficus benghalensis L.
Authors: Singh Preeti , Dhankhar Jyotika , Sharma Asha
Published: October 2023

Plants, being effective antioxidant and antimicrobial agents, continue to play a key role in the healthcare. The present study was conducted to evaluate the antioxidant and the antimicrobial potential of polar (water, methanol and acetone) and non-polar (petroleum ether) extracts of stem bark and aerial root of F. benghalensis L. The total phenol, flavonoid and condensed tannin content exhibited high variation ranging from 75.84 ± 2.70 mg gallic acid equivalent (GAE)/g to 6.24 ± 2.34 mg GAE/g, 71.64 ± 03.71 mg quercetin equivalent (QE)/g to 09.14 ± 2.70 mg QE/g and 19.25 ± 0.58 mg catechin equivalent (CE)/g to 2.03 ± 1.2 mg CE/g respectively. Radical scavenging activity (RSA) was quantified by 2,2-dyphenyl-1-picrylhydrazyl (DPPH) and 2, 2’-azino-bis 3-ethylbenzothiazoline-6-sulphonic acid (ABTS) assay where % RSA ranged considerably. Antimicrobial activity was estimated by investigating zone of inhibition (ZOI) and minimum inhibitory concentration (MIC) against Gram-positive (Bacillus subtilis and Staphylococcus aureus) and Gram-negative (Salmonella typhi and Escherichia coli) bacteria and fungal strains (Aspergillus niger, Fusarium oxysporum and Rhizopus oryzae). The diameter of ZOI ranged from 9.5 ± .88mm to 6.2 ± .88mm for different bacterial strains whereas from 9.2 ± 1.6mm to 6.2 ± .90mm for fungal strains. MIC values ranged between 50μg/μl to 0.024μg/μl against both bacterial and fungal strains. Methanolic extracts were further analyzed using Gas Chromatography-Mass Spectrometry (GC-MS) for their phytochemical profile since they showed higher antioxidant and antimicrobial activity. This study supports the use of Ficus benghalensis L. in microbial infection therapy.
Synthesis, Characterization and biological activity of some novel heterocyclic β-lactam/thiazol compounds derived from 4-phenyl-4,5-dihydrothiazol-2-yl-imino
Authors: Prakash Ram , Singh R.B. , Vishnoi R.K. , Srivastava K.
Published: October 2023

An efficient and convenient synthesis of β-lactam/ thiazol derivatives has been achieved by the reaction of acetophenone, substituted aromatic aldehyde and thiourea yield substituted schiff’s bases which further undergo the cyclization in the presence of chloroacetyl chloride, triethyl amine/ZnCl2, thioglycoolic acid. All the synthesized novel derivatives have been established by % of C, N, S elements, FT-IR, 1H NMR and Mass spectral studies. Further in-vitro antimicrobial activity of novel derivatives was carried out against some Gram-positive and Gram-negative bacteria by serial dilution method. The activity of IIIc, IIId, IIc, IId, IIf derivatives showed significant response against the tested microbes.
Biosorption of Crystal violet, Congo red and Methyl orange on Nephelium lappaceum stem-derived activated carbon and its composite with chitosan
Authors: Abdul Samad Kamdod , Ektha V. , Shika S. , Malladi V. Pavan Kumar
Published: October 2023

Activated carbon was prepared using Nephelium lappaceum stem as the pre-cursor biomass. A bio-composite with chitosan and the activated carbon (NLAC) was synthesized. The activated carbon and the bio-composite were tested for the adsorptive removal of three dyes, namely Crystal violet (CV), Congo red (CR) and Methyl orange (MO), from their aqueous solutions. The characterization of each adsorbent revealed higher value for surface area, satisfactory mechanical strength, higher crystallinity as well as superior porosity. The batch adsorption equilibrium data were best fitted to Langmuir isotherm model. A maximum adsorption capacity of 212.1 mg/g was seen for CV using NLAC. For CR and MO, the maximum adsorption capacitity values were 182.57 mg/g and 64.21 mg/g respectively with CHS-NLAC composite. Electrostatic interaction was the dominant mechanism in the adsorption of the dyes and the rate controlling steps in the adsorption were reasoned in the kinetic studies.
Recent synthetic and biological aspects of 1, 4-dihydro pyridine derivatives
Authors: Garapati Sushma , Lakkoju Babi , Vemulapalli Vandana , Redipalli Gowri Sankar
Published: October 2023

Among the large variety of organic compounds, heterocycles are interesting compounds widely occurring in nature, showing biological activities. Dihydropyridine (DHP) is a privileged scaffold having nitrogen in a six-membered cyclic ring as a central moiety. DHP is a significant compound studied in medicinal chemistry and pharmacology activities. Therefore, organic chemists have made considerable efforts to create new drug candidates with DHP subunits associated with a known or possible pharmacophore. The Hantzsch is a well-studied synthesis of DHP and pyridines and is currently one of the reliable approaches for preparing various DHP derivatives along with new approaches. The most recent studies on diverse synthesis methods for DHP derivatives during the preceding years were highlighted in this study. The main objective of this review is to discuss various approaches for synthesizing dihydropyridine derivatives and documented rife literature on the different pharmacological applications of these versatile scaffold. The supreme importance is given to 1, 4 DHP in the survey according to their pharmacological activity.
development and introduction into the educational system of the Republic of sakha (yakutia) a unified digital pedagogical platform “e-teacher”
Authors: Semenova M. I. , Alekseeva I. S. , Podlinyaev O. L.
Published: October 2023

The article proposes a project for the development and implementation of a unified digital pedagogical platform «E-teacher» into the education system of the Republic of Sakha (Yakutia). The project was developed to solve the problem of replenishing the shortage of teaching staff in the Republic of Sakha (Yakutia). The problem of shortage of teaching staff in the Republic of Sakha (Yakutia) is considered. One of the solutions to the problem is the introduction of a specialized unified digital platform for teachers. All teaching staff of the republic and students of pedagogical specialties will be included in the work of this system. With the successful implementation of the project of a unified digital pedagogical platform «E-teacher», it is possible to solve the problem of replenishing the personnel shortage in the education sector of the Republic of Sakha (Yakutia).
Methodology for teaching Russian as a Foreign in chinese universities with the cooperation of chinese and Russian teachers
Authors: Qian J. , Xiaoxia L.
Published: October 2023

Currently, against the backdrop of strengthening friendship and cooperation between Russia and China, the demand for Russian language specialists with higher education in China continues to grow. This explains the desire of many Chinese universities and institutes to attract Russian teachers to improve the level of their specialist training. The article examines the experience of organizing the educational process by Russian teachers who currently teach Russian in Chinese universities; the existing problems between Chinese and Russian teachers in the organization of training are explored, the solution of which can significantly improve the level of training of specialists in the Russian language in Chinese universities.
The origins of citizen passivity in safeguarding activities on cultural heritage monuments
Authors: Savvinov A. S.
Published: October 2023

The movement to protect cultural heritage is paradoxical because of the relationship between the age of Homo sapiens and the beginning of the movement to protect the best achievements of material culture. The last circumstance is related to a person’s awareness of his own identity. Therefore, the role of the organizational principle put forward by individuals is exceptionally great. A striking example of this is the decision of Pope Benedict XIV. The article discusses the material of public hearings on the protection of historical and cultural monuments in the Republic of Sakha (Yakutia), which took place on July 17, 2015. The author puts forward the idea that the main reason for the social passivity of citizens is the incorrect application of the dialectic of the universal and the unique in the system of positively significant values of human existence, which negatively manifests itself in the upbringing of the younger generation.