bluuebunny/crossref_metadata_2025 huggingface dataset:
Rekrutmen dan Pemeliharaan (Maintenance) Karyawan Disabilitas dalam Perspektif Manajemen Sumber Daya Insani
Authors: Ulum Khozainul , Muflihin Mohammad Dliyaul
Published: August 2022

Abstract: The recruitment and maintenance of employee with disabilities should be handled by company in harmonic context. This research aims at revealing how the recruitment and maintenance for the employees with disabilities practically carried by the company. Qualitative method is applied in this research, while the data are taken from relevant literary sources under the theme of recruitment and maintenance of employees with disabilities. The data, than, are analyzed using descriptive analysis. The findings suggest several points. First, recruitment is the process of searching, recruiting, and finding the competent and reliable employee candidates to deal with certain division, even if they have such disabilities. Being selective while choosing the right candidate is really the crucial key point since all the candidates are competent, smart, responsible, reliable, and expert in their jobs. Second, after obtaining the appropriate candidate, the maintenance toward the employees with disabilities is really a must do. The maintenance can be done by settling the policy of disability, twining the relationship and consulting with organization of employee with disability, adjusting the workplace, and raising awareness of the employees.Â Keywords: recruitment and maintenance; employee with disability; management of human resources
ENGLISH LEXICAL BUNDLES IN THE GRADUATE THESES: THE FREQUENCY, STRUCTURE AND DISTRIBUTION
Authors: Faqih Mohamad Syihabuddin , Harjanto Ignatius
Published: August 2022

Lexical bundles are one of the important characteristics of academic discourse which tell readers to know whether the writer is professional or novice. Inevitably, studies on lexical bundles in scientific essays are important to do. This study identifies the most frequent, structural characteristics, and the functional categorization of lexical bundles in the Master Theses in Teaching English as a Foreign Language (TEFL), specifically in the Findings and Discussion section. There were 651.083 words from 74 different theses compiled to create the corpus by using Antconc 3.5.8. The results found 117 different lexical bundles and the sequences ‘the result of the’ and ‘on the other hand’ dominate the section. Noun phrase + of structure which covers one third of overall forms in the corpus were the most lexical bundles’ structural types in the findings and discussion section followed by other noun phrase structures (22% out of overall bundles). Functionally, research-oriented bundles (45% of overall bundles) were the most frequent ones followed by text-oriented (40%) and the least frequent bundles were participant-oriented. Reported findings are further discussed with related theories.
THE ROLE OF CLASSROOM INTERACTION IN ONLINE LEARNING: VOICES FROM THE STUDENTS
Authors: Entusiastik  , Siregar Yuniar D.A.
Published: August 2022

The importance of classroom interaction in learning has been widely researched. Through the lens of sociocultural theory, classroom interaction could be seen as mediation for learning where learners develop their knowledge and understandings through collaborative activities and dialogic processes which take place during the learning process in class. This paper qualitatively explores the types of classroom interaction that take place in an online learning environment to analyze factors that impacted and shaped classroom interactions. Further, how students perceive each type of interaction and how it might contribute to learning and learners’ satisfaction were also discussed. The study highlights the importance of balancing the use of both synchronous and asynchronous interaction modes to allow maximum classroom interaction. While technology might be a potential tool in encouraging learners to interact more actively and engage in interaction within a less threatening condition, instructors should think carefully about the design of learning activities to create positive classroom interaction with learners, among learners, and between learners and the course materials.
Professional Difficulties of Young Teachers (by the Example of Amur Region Universities)
Authors: Boltenkov Nikolay Vladimirovich , Grinko Andrey Aleksandrovich
Published: August 2022

The study aims to identify negative factors accompanying young teachers’ professional activities at higher education organisations. The paper considers the main trends that have a negative impact on modern teachers under the age of 35 and the specificity of their manifestation at Amur Region universities. Scientific novelty of the work lies in the fact that based on the research relevant to the subject of the paper that was conducted at Amur Region universities among the teaching staff aged 22 to 68, it has been found that young teachers are less stable psychologically than middle-aged teachers, less self-confident, they are characterised by the emerging foundations of emotional burnout. In addition, young teachers are in a less stable position than more experienced employees due to the influence of a whole range of factors, which accounts for the increased turnover among young staff. As a result, the researchers have determined the place of a young teacher in a modern university, have identified the main factors contributing to the decline in the quality and effectiveness of teachers’ professional activities at higher education organisations, have noted regional specifics.
Socio-Cultural Project as the Implementation of an Active Method in the Process of Professional Competence Formation among Future Buryat Language and Literature Teachers
Authors: Dareeva Oksana Alexandrovna , Gunzhitova Garma-Khanda Tsybikzhapovna , Dashieva Soelma Ananduevna
Published: August 2022

The aim of the study is to substantiate the effectiveness of using the project method in the process of professional competence formation among students during the implementation of the socio-cultural project “The Interactive Platform”. The paper describes the implementation of the project method in extracurricular activities of students in the training programme “Pedagogical Education with Two Training Programme Specialisations: Native Language and Literature, Russian Language and Literature” at Buryat State University. The study is novel in that it proposes the idea of using the project method as one of the active teaching methods to increase students’ internal motivation, which is a condition for professional competence formation in extracurricular activities of teacher trainees. As a result of the study, it has been found that project work allowed students to realise the social significance of their future profession, greatly increased their motivation to carry out their future professional activities and contributed to professional competence formation.
Teaching “Effective Reading” in a Foreign Language (Based on IELTS Training Materials)
Authors: Pomortseva Nadezhda Pavlovna , Shigapova Farida Finsurovna , Antropova Anastasia Evgenyevna
Published: August 2022

The aim of the research is to identify the features of teaching “effective reading” in a foreign language (hereinafter - FL) for the successful passing of the Reading section of the International English Language Testing System (hereinafter - IELTS). The paper presents the definitions of the concepts of “reading in FL” and “effective reading in FL”, considers the basic techniques of “effective reading” of FL texts, identifies the main issues encountered by students when completing tasks of the IELTS Reading section and also offers recommendations on using the technology of “effective reading” of FL texts when preparing students for this examination. Scientific novelty of the research lies in developing authors’ recommendations on the use of the “effective reading” technology to improve reading as a speech skill in FL to increase the effectiveness of IELTS preparation. The research findings are as follows: the authors have summarised and clarified the issues that arise when teaching “effective reading”, have classified a number of methods and techniques of “effective reading” in FL, as well as have made recommendations for the successful passing of the IELTS Reading section.
The Context of Designing a Partnership Ecosystem of a Pedagogical University in the New Reality of Education Transformation
Authors: Lozovitskaya Alyona Andreevna , Goloborod’ko Irina Eduardovna , Sapozhnikova Yuliya Andreevna
Published: August 2022

The research aims to substantiate the trends of ensuring the transformation of pedagogical education in the context of actively addressing the discourse of expanding the multidimensional partnership of segments of the educational system at the level of the municipality and the region. The paper considers the aspects of construction, functioning and development of educational ecosystems studied as one of the priority areas of modern education; identifies the relevant formation tracks of a regional ecosystem of the innovative territorial educational cluster, describing the experience of the Rostov Region pedagogical community in the context of understanding the “plots” of interaction between the Taganrog Institute named after A. P. Chekhov (branch) of RSEU (RINH) and the subjects of the general education system among other things. The research is novel in that it substantiates the factors that form the “growth points” of the higher pedagogical education system in the aspect of the content-related and sense-bearing and organisational-methodological components of the functioning of innovative educational ecosystems. As a result, the authors have presented their own vision regarding the possibilities of developing ecosystem cluster models for building an integral educational environment, which act as productive drivers of strategic initiatives of the modern educational policy corresponding to innovative pedagogical trends.
Assessing the Influence of Structural Components of the University Educational Environment on a Future Teacher’s Formation
Authors: Krolevetskaya Elena Nikolaevna , Mikhailova Darya Ivanovna , Shekhovskaya Natalia Leonidovna
Published: August 2022

The research aims to determine the influence of structural components of the university educational environment on the personal, professional, sociocultural formation of a future teacher. The paper sheds light on the essence of the “educational environment”, “educational space” notions within the fundamental theoretical concepts and models of the educational environment. The researchers analysed and provided insight into the specific characteristics of structural components of the educational environment at the Belgorod National Research University, which have a “developing effect”. The research is novel in that it substantiates the structural components of the university educational environment as a set of microenvironments, each of which consists of a structural framework in the form of the spatial-subject component (“space of things”), the event-activity component (“space of events”) and the subject-social component (“space of relations”). As a result, it has been proved that the didactic, practice-oriented, creative and educational microenvironments have the greatest influence on the formation of future teachers in all areas, especially in the “space of relations” component.
Success of Verbs of Motion Mastering by Chinese Students as a Content Component of Teaching Russian as a Foreign Language (by the Example of Delayed Test Survey)
Authors: Mokrishcheva Veronika Sergeevna
Published: August 2022

The aim of the study is to analyze the success of mastering verbs of motion by Chinese students of Belgorod State National Research University in the process of teaching Russian as a Foreign Language. The difficulty of mastering of this component of the program by Chinese students at the preparatory faculty is determined by crosscultural and mental barriers while studying Russian verbs of motion arising from insufficient comparative analysis of Russian verbs of motion and their Chinese equivalents according to differentiating semantic features: direction of movement, mode of transportation and nature of orientation. The scientific novelty of the study lies in identifying difficulties in mastering verbs of motion in the Russian language by Chinese students and substantiating the causes of these difficulties. As a result, practical and methodological recommendations have been formulated for Russian as a Foreign Language teachers on training Chinese students in verbs of motion based on the comparison of Russian verbs of spatial meaning and their Chinese counterparts regarding objective and subjective reference points.
Author’s Electronic Course “English for Mining Engineers” as a Tool for Teaching a Foreign Language to Students of Engineering Specialties
Authors: Shirokolobova Anastasia Georgievna , Larionova Julia Sergeevna , Chistyakova Galina Victorovna
Published: August 2022

The aim of the study is to create and implement the author’s electronic course “English for Mining Engineers” developed in LMS Moodle to realize the educational process of learning a foreign language for students of the Mining Institute. The article deals with the issues of language training of engineering personnel in a technical university in the context of digital transformation of education; describes the organization of educational activity of students of the Mining Institute on the “Foreign Language” discipline based on the principles of digital didactics. The scientific novelty of the research lies in the introduction of new methods for organizing the students’ educational activity in the context of the digital transformation of education by integrating the author’s electronic course “English for Mining Engineers” into LMS Moodle to organize classroom and independent work of students of the Mining Institute of the Kuzbass State Technical University on the “Foreign Language” discipline. The results of the study are the creation of the author’s electronic course “English for Mining Engineers” in LMS Moodle for students of the Mining Institute; identification of the level of formation of language skills and abilities of students of the Mining Institute when learning a foreign language using the author’s electronic course “English for Mining Engineers” in LMS Moodle.
Attention Assessment of Fourth-Grade Schoolchildren
with Dysgraphia within the Framework
of the Basic General Education Program
and the Adapted Basic General Education Program
Authors: Yakovleva Natalia Nikolaevna
Published: August 2022

The aim of the study is to determine the impact of attention functions development on the formation of independent written speech in fourth-grade schoolchildren with dysgraphia. The article presents scientific and methodological foundations for attention development in children with dysgraphia at school age (Grade 4); a comparative analysis of the development of such attention functions as concentration, stability, switchability, distribution in students with dysgraphia studying according to the basic general education program (BGEP) in a speech therapy center and the adapted basic general education program (ABGEP) for students with severe speech disorders. The scientific novelty lies in the addition and description of criteria for assessing the features of attention functions development (concentration, stability, switchability and distribution) that affect the development of such cognitive processes as memory, perception, thinking and ensure the quality of written communication in fourth-grade schoolchildren with dysgraphia. A qualitative interpretation of the development levels of concentration, stability, switchability and distribution of attention has previously been presented in psychological and pedagogical literature in fragments. The results of attention research have shown that schoolchildren with dysgraphia studying according to the BGEP and ABGEP are more affected by the functions of switching and distributing attention, which naturally influences both the formation of learning skills in general and written communication in particular and requires the development of a special system of pedagogical activity including work on the above mentioned functions elaboration.
LA-ICP-MS U-PB AGES OF DETRITAL ZIRCONS FROM SEDIMENTARY ROCKS OF THE KOMSOMOLSKAYA GROUP (NORTHERN SIKHOTE-ALIN)
Authors:   Kosygin Institute of Tectonics and Geophysics, Far East Branch, Russian Academy of Sciences, Kudymov A.V. , Oto Sh. ,   Graduate School of Science and Engineering, University of Toyma, Japan, Arkhipov M.V. ,   Kosygin Institute of Tectonics and Geophysics, Far East Branch, Russian Academy of Sciences, Peskov A.Yu. ,   Kosygin Institute of Tectonics and Geophysics, Far East Branch, Russian Academy of Sciences, Zyabrev S.V. ,   Kosygin Institute of Tectonics and Geophysics, Far East Branch, Russian Academy of Sciences, Nagata M. ,   Graduate School of Science and Engineering, University of Toyma, Japan, Didenko A.N. ,   Kosygin Institute of Tectonics and Geophysics, Far East Branch, Russian Academy of Sciences
Published: August 2022

A geochronological study of detrital zircons from sedimentary rocks of the Gorinskaya (91 zircons with concordant ages), Pionerskaya (117 zircons with concordant ages), and Pivanskaya (115 zircons with concordant ages) formations of the Komsomolskaya Group was carried out. Comparison of the 206Pb/238U isotopic age of the youngest zircon populations from these formations with their stratigraphic age revealed that they are consistent only for one of them (Pivanskaya Formation). For the other two formations, the youngest zircons turned out to be significantly younger than the upper limit of their stratigraphic age. New evidence shows that: 1) the age of the «Berriassian-Valanginian» deposits of the Pionerskaya Formation is not older than the Barremian; and 2) the age of the «Titonian-Berriasian» deposits of the Gorinskaya Formation is not older than the Hauterivian. The division of deposits in the Komsomolskaya Group into formations is based primarily on lithological criteria, and since the composition of the formations is very similar, similar deposits in other Lower Cretaceous sections of the region may have been assigned to other stratigraphic units, so the above conclusion is valid only for the sections we studied.
Evaluation of Pre-conflict International Olympic Committee Actions against Russia for Doping Violations
Authors: Stefani Raymond
Published: August 2022

It is sadly ironic that in ancient Greece, wars were stopped for the Olympics, whereas during the period of the Olympic Truce for the 2022 Beijing Olympics and Paralympics, Russia began an armed incursion into Ukraine. For some time to come, Russia will suffer serious sanctions against competing in the Olympics and in many other international competitions. When Russia is again allowed to compete in the Olympics, there will remain the issue of insuring that the Russian athletes are no longer gaining an advantage by taking performance- enhancing drugs. Although it would seem that the International Olympic Committee (IOC) has been punishing Russia for its past doping transgressions, most of the IOC actions were not sanctions at all, based on the Olympic Charter. However, some previous actions were punitive and could force compliance if reinstituted and increased. The Russian Olympic Committee (ROC) should be disenfranchised. Russian athletes should compete simply as Olympic Athletes with no mention of Russia and no medal table should include Russian-earned medals. The IOC should exercise its ability to screen all Russian athletes for past and present use of performance-enhancing drugs. Further, Russia should not compete in team sports until there is compliance with anti-drug standards. Keywords: anti-doping, Russian sports doping, medals stripped, IOC sanctions
DICTADURA, PODER ESTATAL Y GRANDES PROYECTOS EN REGIONES MARGINALES. LA AMAZONIA BRASILEÑA Y LA PATAGONIA ARGENTINA DURANTE LA DÉCADA DE 1960 Y 1970
Authors: Martins de Souza César , Ruffini Martha
Published: August 2022

En América Latina, las décadas de 1960 y 1970 estuvieron atravesadas por regímenes dictatoriales que procuraban evitar el cuestionamiento de la dominación mediante el control social, en alianza con los intereses nacionales y transnacionales en pos de la expansión del capitalismo. Tanto en Brasil a partir de 1964 como en Argentina desde 1966, los gobiernos militares procuraron visibilizar el poder a través de grandes proyectos ubicados fundamentalmente en áreas consideradas marginales. En la Amazonia brasileña como en la Patagonia argentina, los megaproyectos formaron parte de un constructo ideológico destinado a resignificar esos espacios como parte de una política de crecimiento económico. El discurso oficial basado en la premisa del progreso, la grandeza y el desarrollo nacional se orientó a legitimar a la dictadura y acrecentar el consenso social. Este artículo se realiza sobre la base de fuentes primarias, fundamentalmente discursos presidenciales, artículos de revista y documentación oficial de organismos nacionales e internacionales.
Para abrir a Ciência Odontológica
Authors: Zanetti Carlo Henrique Goretti , Sousa Nétto Otacílio Batista de
Published: August 2022

O propósito desse texto é relatar a experiência iniciada em 2016 de giro epistêmico da disciplina Práticas de Saúde (DSC/UnB) para alinhá-la ao esforço pragmático de formar estudantes mais capazes de atribuir sentido e valor à sua presença futura em cenários complexos de prática, tais como os campos de estágio no SUS. O artigo considera que sem a Ciência Moderna não seria possível consolidar as profissões da saúde como profissões igualmente modernas, mas problematiza a perspectiva epistêmica (reducionista e positivista) que suporta suas teorizações, e compreende a cultura científica vigente como obstáculo, seja para a atualização dos referenciais epistêmicos, seja para uma formação democrática que considere a pluralidade dos discursos no interior da cultura. Apresenta as dificuldades institucionais nos cursos de saúde da UnB para introduzir os estudantes dos períodos iniciais em atividades de campo no SUS, e justifica a opção de apostar na pragmática como antecipação à práxis, de fazer a ação do discurso como acumulação para ações subsequentes de intervenção em campo. Nesse contexto, optou-se pela estratégia de extensão ao contrário (extensão inversa, reversão da extensão) para abrir o diálogo de saberes com outras comunidades epistêmicas na formação profissional universitária. O artigo descreve o processo e faz uma análise críticoreflexiva do mesmo.
Karakteristik Peternakan Wilayah Sumber Bibit Sapi Peranakan Ongole dan Penyediaan Hijauan Pakannya di Kabupaten Gunungkidul
Authors: Zuljisman Zuljisman , N.R Kumalasari , L Abdullah
Published: August 2022

Peternakan sapi rumpun Peranakan Ongole (PO) di Kabupaten Gunungkidul sebagai wilayah sumber bibit ternak ditetapkan melalui Keputusan Menteri Pertanian. Mendukung penetapan tersebut, pakan hijauan sebagai sumber pakan utama memegang peranan penting dalam pengembangan peternakan ruminansia potong. Penelitian dilakukan dengan survey untuk investigasi pola penyediaan hijauan pakan saat ini pada kelompok ternak peternakan wilayah sumber bibit sapi PO di Kabupaten Gunungkidul. Penelitian survey ini dilakukan pada bulan Februari tahun 2022 di Kecamatan Playen dan Wonosari secara purposive sampling kelompok peternak sapi PO. Statistik deskriptif digunakan untuk menggambarkan ciri-ciri dasar data dalam penelitian ini. Hasil penelitian menunjukan bahwa kecilnya skala kepemilikan ternak sapi antara 1-6 ekor, atau rata-rata 2,78 ekor per peternak. Jumlah ini menunjukan kecilnya skala kepemilikan ternak yang dipelihara. Karakteristik responden terhadap sistem pemeliharaan intensif dapat diaplikasikan peternak dengan penyediaan hijauan pakan cukup hingga banyak dan luas lahan hijauan pakan ternak yang variatif. Peternak pada umumnya menyediakan pakan ternak ruminansia dalam jumlah yang cukup sesuai dengan kebutuhan ternak. Jenis hijauan tergantung pada ketersediaan hijauan di sekitar lokasi peternakan.
The Performance of the Uterine Artery Resistance Index following Stimulation of the Cervix in the Diagnosis of Endometriosis: A Prospective Study
Authors: Jia Su-Hong , Sun Hong , Wei Ying , Ma Qi , Ren Qiong-Zhen , Shao Min-Fang , Jin Yu-Ma , Xie Yuan
Published: August 2022

Background: We speculated that stimulating the uterine cervix of patients may increase blood flow resistance of the uterine artery more significantly in women with endometriosis than those without. Accordingly, the resistance index (RI) of the uterine artery following stimulation of the cervix may offer a novel and promising non-invasive method for diagnosing endometriosis. In this prospective study, the aim was to determine the performance of the uterine artery resistance index (RI) following stimulation of the cervix in the diagnosis of endometriosis. Methods: This prospective cohort study included 270 patients with non-uterine diseases who were scheduled for laparoscopic surgery. Each patient underwent Doppler sonography for peak systolic velocity (PSV), end diastolic velocity (EDV), and RI before and after stimulation of the cervix, in addition to conventional ultrasound examination one day prior to laparoscopic surgery. The cervix was stimulated using a double convex array electronic vaginal probe for real-time tissue elastography. Results: Laparoscopic surgical evaluation revealed endometriosis in 91 (33.7%) patients. Following stimulation of the cervix, the RI of the uterine artery was significantly increased in the endometriosis group (p = 0.00), but no significant increase in the RI was observed in the control group (p = 0.45). The sensitivity and specificity of the post-stimulation RI for diagnosing endometriosis (using a cut off of 0.83) were 85.71% (95% confidence interval (CI): 76.45–91.88) and 88.83% (95% CI: 83.05–92.87), respectively. For peritoneal endometriosis (PEM), sensitivity and specificity were 86.96% (95% CI: 65.33–96.57) and 88.83% (95% CI: 83.05–92.87), respectively. The sensitivity and specificity of transvaginal ultrasonography (TVU) for diagnosing endometriosis were 63.74% (95% CI: 52.93–73.37) and 94.41% (95% CI: 89.68–97.14), respectively. The positive rate for TVU in diagnosing all endometrioses was 63.7%, and this was lower than that for the post-stimulation RI (84.6%, p = 0.001). Conclusions: Stimulation of the cervix leads to a significant decrease in uterine blood perfusion in women with endometriosis. TVU is a sensitive and specific method for the diagnosis of endometrioma, while the RI is a more sensitive parameter for diagnosing PEM than TVU. For the diagnosis of endometriosis, especially for PEM, the post-stimulation RI may prove to be a promising non-invasive diagnostic technique.
Differential expression of NFRKB in amyotrophic lateral sclerosis.
Authors: Mamoor Shahan
Published: August 2022

Neurodegenerative diseases that affect the motor neurons, including amyotrophic lateral sclerosis (ALS), have little treatment options and are generally rapidly fatal (1, 2). We harnessed the power of unbiased, whole transcriptome differential gene expression analysis, utilizing primary patient cells and tissues to discover genes whose expression defines sporadic ALS using published data (3, 4). We found significant differential expression of NFRKB, encoding nuclear factor related to kappaB binding protein, in primary fibroblasts of patients with sporadic ALS (SALS). NFRKB transcript was present at significantly lower levels in SALS patient fibroblasts as compared to control, non-diseased fibroblasts. These analyses will begin to define the transcriptional landscape of sporadic ALS.
On the use of percent change within rehabilitative ultrasound imaging research: a systematic review with Monte Carlo simulations
Authors: Fernández-Matías Rubén , Tu Yu-Kang , Koppenhaver Shane
Published: August 2022

Objective: The aim of this study is to review the reasons reported within rehabilitative ultrasound imaging (RUSI) research for using percent change, and to conduct Monte Carlo simulations to evaluate the statistical assumptions, statistical power, reliability, and type 1 error rate regarding this practice.Design: Systematic review with Monte Carlo simulations.Literature search: A systematic search of Medline, EMBASE, Web of Science, SPORTDiscus, Scopus, and Cochrane Library was performed on 1st of August 2022.Study selection criteria: Studies measuring percent change of muscle thickness with RUSI procedures.Data synthesis: Narrative synthesis was conducted regarding study design, measured muscles, reasons reported for using percent change and if they evaluated assumptions for using percent change. Monte Carlo simulations were conducted to compare statistical assumptions, statistical power, reliability, and type 1 error rate of percent change measures with contracted muscle estimates obtained with multiple linear regression (MLR).Results: 720 studies were retrieved and 59 were included. No reason for using percent change was reported in 47 (77.2%) of the included studies. The most common reported reason was to normalize muscle thickness during contraction (12.3%). Monte Carlo simulations showed that MLR performs better regarding statistical power than percent change for a wide range of situations.Conclusions: There is a lack of reported justification for using percent change within RUSI research. Monte Carlo simulations show that percent change is statistically inefficient, and MLR including rest thickness as a covariate should be used instead.
Soviet computing, microchip precedence fight, early digital cash (historiography VI:2)
Authors: Akmut Camille
Published: August 2022

Computer science and technology : historiography VI (2)
The Primordial Dynamic Space (Introduction 1)
Authors: Di Sia Paolo
Published: August 2022

Introduction 1 to the "Primordial Dynamic Space"
Differential expression of BANK1 in amyotrophic lateral sclerosis.
Authors: Mamoor Shahan
Published: August 2022

Neurodegenerative diseases that affect the motor neurons, including amyotrophic lateral sclerosis (ALS), have little treatment options and are generally rapidly fatal (1, 2). We harnessed the power of unbiased, whole transcriptome differential gene expression analysis, utilizing primary patient cells and tissues to discover genes whose expression defines sporadic ALS using published data (3, 4). We found significant differential expression of BANK1, encoding B-cell scaffold protein with ankyrin repeats 1, in primary fibroblasts of patients with sporadic ALS (SALS). BANK1 transcript was present at significantly lower levels in SALS patient fibroblasts as compared to control, non-diseased fibroblasts. These analyses will begin to define the transcriptional landscape of sporadic ALS.
Gravity or Magnetic Monopoles? You Cannot Have Both! II
Authors: Maes Stephane
Published: August 2022

In this paper, we argue that gravity breaks the symmetry between electric and magnetic equations (without sources) within the Standard Model. As a result, the motivation for introducing magnetic monopoles disappears (without affecting charge quantization): magnetic monopole probably do not exist in the presence or gravity. It is consistent with the absence of observation of magnetic monopoles and resolves the magnetic monopole cosmology problem. This result could have serious implications for supersymmetry, supergravity, GUTs and ToEs, including in particular superstrings. Some of these implications, and possible ways forward, are discussed.
Experience of irreproducibility as a risk factor for poor mental health in biomedical science doctoral students: A survey and interview-based study
Authors: Lubega Nasser , Anderson Abigail , Nelson Nicole Christine
Published: August 2022

High rates of irreproducibility and of poor mental health in graduate students have been reported in the biomedical sciences in the past ten years, but to date, little research has investigated whether these two trends interact. In this study, we ask whether the experience of failing to replicate an expected finding impacts graduate students’ mental health. Using an online survey paired with semi-structured qualitative interviews, we examined how often doctoral students at a large American public university experienced events that could be interpreted as failures to replicate and how they responded to these experiences. We found that almost all participants had experience with irreproducibility: 84% had failed to replicate their own results, 70% had failed to replicate a colleague’s finding, and 58% had failed to replicate a result from the published literature. A majority (82%) of participants initially believed that the anomalous results could be attributed to their own error. However, after further experimentation, most participants concluded that the original result was wrong (38%), that there was a key difference between the original experiment and their own (17%), or that there was a problem with the protocol (17%). Participants reported feelings of self-doubt, frustration, and depression while experiencing irreproducibility, and in 24% of cases, these emotional responses were strong enough to interfere with participants’ eating, sleeping, or ability to work. These results suggest that biomedical science graduate students may be biased towards initially interpreting failures to replicate as indicative of a lack of skill, which may trigger or perpetuate feelings of anxiety, depression, or impostorism.
Tailoring Interventions to Suit Self-Reported Format Preference Does Not Decrease Vaccine Hesitancy
Authors: Mäki Karl Otto , Karlsson Linda C. , Kaakinen Johanna K. , Schmid Philipp , Lewandowsky Stephan , Antfolk Jan , Soveri Anna
Published: August 2022

Individually tailored vaccine hesitancy interventions are considered auspicious for decreasing vaccine hesitancy. In two studies, we measured self-reported format preference for statistical vs. anecdotal information in vaccine hesitant individuals, and experimentally manipulated the format in which COVID-19 and influenza vaccine hesitancy interventions were presented (statistical vs. anecdotal). Regardless of whether people received interventions that were in line with their format preference, the interventions did not influence their vaccine attitudes or vaccination intentions. Instead, a stronger preference for anecdotal information was associated with perceiving the material in both the statistical and the anecdotal interventions as more frustrating, less relevant, and less helpful. However, even if the participants reacted negatively to both intervention formats, the reactions to the statistical interventions were consistently less negative. These results suggest that tailoring COVID-19 and influenza vaccine hesitancy interventions to suit people’s format preference, is not a viable tool for decreasing vaccine hesitancy. The results further imply that using statistics in interventions with people who hold anti-vaccination attitudes may be a less risky choice than using anecdotal testimonies.
Folk Explanations of Aggressive Behaviors
Authors: McCarthy Randy J.
Published: August 2022

Unsurprisingly, victims and perpetrators often view aggressive behaviors differently. The current study examined whether victims, perpetrators, and witnesses also explained aggressive behaviors differently. The current study included 408 participants who recalled a time when they harmed another person (i.e., perpetrator memory), when another person harmed them (i.e., victim memory), and when they witnessed an aggressive behavior (i.e., witness memory). Replicating past research, participants rated their recalled aggressive behaviors from the victim perspective as being more harmful and less justified than they did for their recalled behaviors from the perpetrator perspective. When examining their explanations for the behaviors, participants most often explained their own aggressive behaviors by referring to their mental deliberations that led to their behavior (i.e., reason explanations). In comparison, they referred to background causal factors (i.e., causal history of reasons explanations)—such as personality traits, demographic factors, cultural norms, etc.—more when explaining others’ aggressive behaviors. These findings show the subtleties in how people communicate about their aggressiveinteractions: When communicating about their own aggressive behaviors, people use modes of explanations that portray their behaviors as sensible, and when communicating about a time when another person behaved aggressively towards them, people use modes of explanations thatomit the thought processes that led to those behaviors.
Self-Reported Cognitive Decline Among Middle and Older Age Autistic Adults
Authors: Klein Claire , McQuaid Goldie , Charlton Rebecca Ann , Klinger Laura , Wallace Gregory
Published: August 2022

Very little is known about autistic adults as they age. Early evidence suggests a potentially high risk for dementia and atypical cognitive decline in autistic middle age and older adults. Research in the general population indicates that self-reported cognitive decline may predict future dementia earlier than performance-based measures. Nevertheless, self-report dementia screeners have not been used to date in autism research. Therefore, in a sample of middle and older age autistic adults (N=210), participants completed a self-rated dementia screener, the AD8, to describe the prevalence of cognitive decline, to examine associations of cognitive decline with age, sex designated at birth, and autistic traits, and to document the psychometrics of a dementia screener in autistic adults. We found high rates of cognitive decline with 30% of the sample screening positive. The most common symptoms were declining interest in leisure activities, and increases in everyday problems with thinking, memory, and judgment. There was evidence that autistic individuals designated female at birth may be more vulnerable to cognitive decline than autistic individuals designated male at birth. Notably, reports of cognitive decline did not vary by age. Modestly elevated autistic traits were found in those screening positive versus negative for cognitive decline. Finally, the psychometrics of the dementia screener were good, including convergent validity with an independent measure of current memory problems. These results could signal an emerging public health crisis in autistic adults as they age, and support the potential utility of self-report measures for early screening for cognitive decline in this population.
प्रकरणार्थविज्ञानका आधारभूत अवधारणा: प्रतिज्ञप्ति, पूर्वधारणा, निहितार्थ र अभिव्यञ्जना {Basic concepts of epistemology: Promises, preconceptions, implications and expressions}
Authors: भुसाल Bhusal केशव Keshav
Published: August 2022

प्रस्तुत लेख प्रायोगिक भाषाविज्ञानको महत्वपूर्ण क्षेत्र प्रकरणार्थविज्ञानमा आधारित रहेको छ । यस लेखमा प्रकरणार्थविज्ञानका आधारभूत अवधारणाअन्तर्गत पर्ने प्रतिज्ञप्ति, पूर्वधारणा, निहितार्थर अभिव्यञ्जनाको सूक्ष्म अन्वेषण गरिएको छ । प्रकरणार्थविज्ञानको परिचय दिनु, प्रतिज्ञप्ति,पूर्वधारणा, निहितार्थ र अभिव्यञ्जनाको सैद्धान्तिक चर्चा गर्नु, यीअन्तर्गतका विभिन्न भेदोपभेदको व्याख्या विवेचन गर्नु यस अध्ययनका मूलभूत उद्देश्यहरू रहेका छन् । प्रस्तुत अध्ययन गुणात्मक अनुसन्धान विधिमा आधारित रहेको छ । यस अध्ययनमा मूलतः द्वितीयक स्रोतका सामग्रीहरूको प्रयोग गरिएको छ । यस क्रममा पुस्तकालयीय कार्यका माध्यमबाट आवश्यक सामग्रीहरूको सङ्कलन गरिएको छ । यो लेख तयार गर्ने सिलसिलामा अङ्ग्रेजी सैद्धान्तिक सामग्रीहरूकोअधिक उपयोग गरिएको छ । यस अध्ययनबाट प्रकरणार्थविज्ञान प्रकरणपरक भाषिक प्रयोगकोअध्ययनसँग सम्बन्धित रहेको, प्रतिज्ञप्ति भाषिक अभिव्यक्ति वा उच्चारबाट प्रकट हुने आधारभूत अर्थसँग सम्बन्धित रहेको, पूर्वधारणा व्यक्त अभिव्यक्तिका आधारमा अव्यक्त अभिव्यक्तिको अनुमान गर्ने कार्यसँग सम्बन्धित रहेको, निहितार्थ प्रतिज्ञप्तिहरूका बिचको सम्बन्धसँग सम्बन्धित रहेको, अभिव्यञ्जना भाषिक अभिव्यक्तिमा व्यक्त अभिधार्थभन्दा भिन्न लक्ष्यार्थसँग सम्बन्धित रहेको लगायतका निष्कर्ष निकालिएको छ । प्रस्तुत अध्ययन प्रकरणार्थविज्ञान र यसअन्तर्गत पर्ने प्रतिज्ञप्ति, पूर्वधारणा, निहितार्थ र अभिव्यञ्जनाका बारेमा आवश्यक जानकारी लिन विशेषोपयोगी हुने अपेक्षा गरिएको छ ।
Strategi Komunikasi Dinas Perpustakaan Kabupaten Polewali Mandar dalam meningkatkan Minat Baca Pemustaka
Authors: Syaeba Muhammad , Masyhadiah Masyhadiah
Published: August 2022

The purpose of this study was to determine the communication strategy used by the Polewali Mandar Regional Library and Archives Service in increasing reading interest, especially in the Polewali Mandar area. The method in this study is a qualitative research method, the researchers conducted in-depth interviews with informants, namely the librarian of the Polewali Mandar Regency Library and Archives Service. The results showed that the communication strategy carried out was aimed at the community and school students. The message conveyed is the activities held in order to increase interest in reading the program targets. The impact is very good because the enthusiasm of the community and school students is very high in welcoming activities in the form of storytelling competitions and speaking competitions at the central level, in collaboration with literacy groups in Balanipa and mobile library activities. the implications of this communication strategy are very clear changes in the increase in reading interest, in 2018 elementary school students, namely 41% boys, 45% female elementary school students then in 2019 there was an increase in reading interest in elementary school students, namely male students increased 44% and female students to 46%, there is real progress from the communication strategy that has been implemented to increase interest in reading.Keywords: Communication Strategy, Interest in Reading, Library. Regional Library and Archives Service
Acute hepatitis following mRNA BNT162b2 COVID-19 vaccination
Authors: Cheah Matthew , Girgis Safwat , Bain Vincent G
Published: August 2022

BACKGROUND: Widespread administration of COVID-19 vaccinations have led to reports of rare but potentially serious side effects. METHODS: We present two cases of acute hepatitis following mRNA BNT162b2 (Comirnaty, Pﬁzer-BioNTech) vaccination. RESULTS: A 25-year-old male presented to hospital with progressive jaundice 5 days following his second dose of Comirnaty. Initial bloodwork revealed severe hepatocellular enzyme elevation and conjugated hyperbilirubinemia with preserved INR. Extensive serologic workup was negative, with normal imaging. Percutaneous liver biopsy was performed and revealed acute cholestatic hepatitis possibly related to drug-induced liver injury. He was started on prednisone 40 mg daily with good initial response but had a second flare; a biopsy was repeated which showed near-identical findings. Steroids were discontinued given non-response and the patient had gradual near complete resolution of liver enzymes and hyperbilirubinemia. A 32-year-old male presented with a 4-week history of nausea followed by progressive choluria, jaundice, and pruritis. He received his second dose of Comirnaty vaccination two weeks prior to presentation. Initial bloodwork showed mixed enzyme elevation with hyperbilirubinemia. Serological workup and imaging were unrevealing. He underwent liver biopsy which showed severe intrahepatic cholestasis, with drug-induced liver injury being suggested as most likely cause. His course was self-limited with resolution of serological abnormalities and symptoms. CONCLUSIONS: While overwhelmingly safe on a population level, our case series illustrate two cases of acute icteric hepatitis following mRNA BNT162b2 vaccination. Clinicians should be aware of this association with hepatic inflammation and consider vaccine history an important component of evaluating patients with acute liver injury.
Prevalence of syphilis coinfection in hepatitis C virus positive prenatal patients from Alberta during a pilot routine screening program
Authors: Thompson L Alexa , Plitt Sabrina S , Gratrix Jennifer , Charlton Carmen L
Published: August 2022

BACKGROUND: Alberta routinely screens pregnant patients for select communicable diseases. Hepatitis C virus (HCV) was added to the prenatal screening panel as part of a provincial pilot program in February 2020. This retrospective cross-sectional study aimed to characterize the prevalence of syphilis coinfections in prenatal patients infected with HCV following implementation of the pilot program. METHODS: Routine prenatal HCV and syphilis testing data were extracted from the Public Health Laboratory Information System over a 21-month period. HCV positivity was defined as HCV enzyme immunoassay (EIA) reactive with detected HCV ribonucleic acid (RNA) following molecular confirmation, and positive results were examined for syphilis coinfections. All patients reactive on a syphilis EIA and confirmatory Treponema pallidum particle agglutination (TPPA) or follow-up rapid plasma reagin (RPR) test were considered positive for syphilis. Descriptive statistics for coinfected patients were analyzed. RESULTS: Eighty-seven prenatal patients were identified to be positive for HCV. Of those, 19 (21.8%) were reactive on the syphilis EIA and 17 (19.5%) had confirmed infections with the TPPA or RPR tests. For HCV/syphilis coinfected patients, the majority resided in metropolitan regions (64.6%), were from the lowest income quintile neighbourhoods (47.1%) and had previously tested positive for HCV (82.4%) and syphilis (64.6%) at the public health laboratory. CONCLUSIONS: The prevalence of syphilis coinfections in prenatal patients infected with HCV is high in Alberta. HCV/syphilis coinfection prevalence should be further investigated in other jurisdictions and prenatal cohorts to better understand testing and treatment options for prevention of congenital transmission.
A LITERATURE REVIEW ON EUROPEAN INTEGRATED BORDER MANAGEMENT
Authors: Yao Xuedan
Published: August 2022

In the wake of the Schengen Agreement, the EU has assumed the role of maintaining European security, and border integration management has been ranked among the top priorities for the EU. It is necessary to improve border integration management to advance the integration process. Despite this, border integration management in the EU has been challenging, particularly since the refugee crisis of 2015. This article analyzes the current directions and trends of relevant research on border integration management in the EU. Three main areas of research on border integration management are currently being conducted: migration policy, border control agency, and border integration problems. The study concluded that theoretical and organizational analysis need to complement border management research.
علماء كشمير؛ تراجم وجهودهم في الدراسات العربية
Authors: شيخ مظفر أحمد
Published: August 2022

كشمير منطقة خصبة أنجبت عددًا كبيرًا من جهابذة العلماء وفطاحل الأدباء الذين أسهموا في نشر العلوم الإسلامية وتطوير اللغة العربية وآدابها على مر العصور. ونالوا قبولًا واعترافًا في العالم الإسلامي والعربي على السواء. إن كل ما نرى من آثار اللغة العربية وآدابها في كل بقعة من بقاع جامو وكشمير وناحية من نواحيها يرجع الفضل فيه بعد فضل الله عزوجل إلى العلماء البارزين الذين أصبحوا منارًا في مجال التعليم والتربية والتأليف ووصلوا إلى قمة الشهرة بمؤلفاتهم في العربية. وهذه حقيقة ناصعة أن علماء جامو وكشمير قاموا بمساهمات قيمة في تطوير اللغة العربية وآدابها منذ بداية الإسلام في الهند، وبرز نخبة من النبلاء والأدباء قديمًا وحديثًا، هم تركوا آثارًا خالدة في مجال التفسير والحديث والفقه والتصوف والفلسفة والتاريخ والسيرة والنحو وعلوم اللغة والأدب، والبلاغة والشعر، وهناك قائمة طويلة للكتاب البارزين الذين لهم مساهمة كبيرة بمؤلفاتهم المرموقة وكتاباتهم الأدبية، واعترف العرب بفضلهم وتضلعهم وتمكنهم في اللغة العربية وآدابها كتابة وخطابة وتكلمًا وتحدثًا. ولا تقل قيمتها العلمية والأدبية أمام روائع التراث الإسلامي التي أنتجتها مراكز العروبة ومدن العالم العربي، كما أنهم شاركوا مشاركة فعالة في نشر الإسلام والثقافة الإسلامية.