bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluation of Wound Healing Activity of Teucrium polium on Excisional Wounds in Wistar Rats
Authors: Yassine Kalbaza Ahmed , Houari Hemida , Eddine Rezgui Houssam , Younes Hamouta , Mokhtar Benchohra , Karim Amara
Published: May 2023

Background: Teucrium polium a member of Lamiaceae family is a widely used plant in Algerian traditional medicine; however, there are few reports on its use as a healing agent. The aim of this study is to investigate the wound healing property of aerial part of this plant on excisional wounds. Methods: Twenty adult male Wistar rats with an average weight of 180 g were used in this study. Post wound development, 10 rats received daily treatment with the plant ointment and the remaining rats served as control. Measurement of wound areas and calculation of closure percentages were made in order to evaluate wound healing macroscopically and a sample of the scar tissue formed was submitted at day 24 post treatment for a histological study. Result: Better and faster healing was observed in the Teucrium polium group compared to control. This improvement in wound healing was confirmed by the histological study which revealed that the effect of the plant lies in its stimulation of proliferative phase and its regulation of the inflammatory phase of wound healing. Based on these results, we could deduce that Teucrium polium enhance healing of excisional wounds.
Economic Evaluation of Magmeal for Quail Feed as a Remunerative Poultry Feed in India
Authors: Mohapatra S.S. , Suganya G. , Leela V. , Latha B.R.
Published: May 2023

Background: Maggot meal, popularly magmeal is a core product consisting of dried defatted larvae that is ground into a high protein larvae meal. It is a potential alternative for fish replacement in the diet of quails. Methods: A study on 240 Japanese quail birds from day old to six week of age was conducted at Poultry Research Station, Madhavaram Milk Colony, Chennai with magmeal supplementation during the year 2015-16. The birds were divided into four groups and each having with three replicates with 20 birds in each replicate. Group 1 (Control group) was fed basal diet (with 7% fish meal), group 2 was fed basal diet replacing 50% fish meal with magmeal, group 3 was fed basal diet replacing 75% fish meal with magmeal and group 4 was fed with Japanese quail basal diet replacing 100% fish meal with magmeal. Economic evaluation of magmeal at various levels of inclusion in Japanese quail diet was calculated. Result: There was a sizeable reduction in the cost of production in all the treatment groups when compared to control group. It is concluded that feed containing magmeal was found to be cost effective than the feed containing fishmeal for the Japanese quails.
SSR Marker-based Molecular Characterization of Lentil (Lens culinaris Medik.) Genotypes
Authors: Tomar Shraddha , Sharma Stuti , Tripathi Niraj , Thakur Sunny , Pathak Nidhi , Sharma Radhyeshyam , Tiwari Priya
Published: May 2023

Background: Lentil is an important legume crop that plays a vital role in sustainable agriculture and human health. However, the restricted genetic foundation or parentage of contemporary cultivars has arisen as a serious challenge for lentil development. Therefore, determining the genetic diversity and yield-related characteristics is crucial for the breeder to broaden the genetic base and aid in selecting the desirable parents for hybrid development programmes. Methods: In the current study, microsatellite markers were used for diversity analysis among 37 lentil genotypes. Morphological and molecular systems both were able to differentiate lentil genotypes. Among applied SSR primers 10 were able to produce successful amplifications with template DNA of all the studied genotypes of lentil. Result: A sum of 357 scoreable bands were produced, 148 of which accounted for 41.45% polymorphism. The UPGMA dendrogram grouped 37 lentil genotypes into 2 groups. PIC values ranged from 0.37 to 0.77. For this experiment, SSR 80, SSR 130, SSR 34-2 and SSR 33 were highly informative polymorphic markers, demonstrating the efficacy and higher resolution in exposing molecular genetic diversity among lentil genotypes. The highest numbers of alleles (5) were produced by SSR 80 primer which was selected as extremely polymorphic. This study reveals the variation across lentil genotypes, which might be employed further in breeding efforts for lentils that result in strong heterosis in the segregating generation. The SSR markers found as polymorphic may also be utilized for further polymorphism analysis among different set of lentil genotypes.
‘Muchness’ as the subjective experience of wellbeing: sharing the findings of a participatory inquiry with nurses
Authors:   Foundation of Nursing Studies, Sanders Kate
Published: May 2023

Background: I discovered the concept of muchness when reading a blog that considered quotes from Alice in Wonderland to identify what meaning they could offer healthcare. One was from the Mad Hatter: ‘You used to be much more “muchier”. You’ve lost your muchness.’ Reflecting on my experiences of working with nurses who reported feeling overworked, undervalued and undermined, I questioned whether some nursing staff had lost their muchness – their subjective experience of wellbeing. Aims: The research aimed to work with nurses to explore two research questions: What is muchness? How can muchness be nurtured? Methods: An innovative research method was developed – Virtual Picture Voice. This enabled nurses to create and share ‘stories of muchness’ and then participate in their analysis and synthesis, contributing to the creation of the Muchness Model Version 1. A metasynthesis process followed, drawing on wider theoretical understandings and resulting in the development of the Muchness Model Version 2. Findings: Version 2 advocates for a ‘full-life’ understanding of wellbeing – a balance between the pursuit of feeling fulfilled and feeling good, facilitated by reflection and action. Conclusions: A holistic approach to the facilitation of wellbeing can enable nurses to identify what is important/matters to them, personally and professionally. Critical reflection on self, our relationships and the contexts in which we work can generate knowledge to inform actions towards experiencing subjective wellbeing in the workplace. Implications for practice: Creative approaches to self-inquiry can facilitate access to experiential and embodied knowledge, informing actions that facilitate wellbeing The Muchness Model Version 2: – can stimulate critical reflection and dialogue with self and others, helping identify factors that enable or limit muchness and potentially informing action at individual, team and organisational levels – offers a person-centred approach to the facilitation of wellbeing in nurses across the career trajectory and within leadership and culture-change programmes
A critical reflection on the transformation from bachelor of nursing student to researcher
Authors:   University of Wollongong, Wollongong, New South Wales, Australi, Kell Meg , Marriott-Statham Kelly ,   University of Wollongong, Wollongong, New South Wales, Australi, Mackay Maria ,   University of Wollongong, Wollongong, New South Wales, Australi
Published: May 2023

Background: The school of nursing at the University of Wollongong developed an innovative approach entitled the ‘Students as Researchers Internship’ to provide an opportunity for students who identify as Aboriginal or Torres Strait Islanders to experience research as co-researchers. This programme was developed in response to a need to increase the number of Aboriginal and Torres Strait Islander persons who complete research degrees and progress to academic careers in nursing. The initial programme included two students who identified as Aboriginal women in their final year as bachelor of nursing students, with both employed as research assistants. Aim: This article aims to share the students’ perspective of their learnings from participating in the Students as Researchers Internship programme through a critical reflection using the Mezirow model of reflection. Conclusion: The opportunity to be a research assistant and co-researcher during the final year of the bachelor of nursing degree offered the students a platform to gain skills, and an understanding of the research process and the application of research in practice. It also provided the experience of being supported in their academic studies. Implications for practice: Mezirow’s model of reflection provides an effective framework for students to unearth their assumptions and learnings from experience Developing skills and experience in research can transform undergraduate students’ understanding of the application of research in their practice Participation in writing ethics applications and research publications offers students insight into the skills of referencing, academic writing and critical thinking The experience as co-researchers enabled students who identify as Aboriginal or Torres Strait Islanders to consider future career opportunities in research
A formação profissional para o atendimento à comunidade surda: um estudo da formação básica em LIBRAS em Juazeiro, BA
Authors: Tôrres Fabiana Pionório , Silva Flaviane Maria Florêncio Monteiro , Tenório Pedro Pereira , Tôrres Ednaldo Ferreira
Published: May 2023

Este trabalho busca analisar os impactos da formação em Língua Brasileira de Sinais (LIBRAS) para a inserção no mercado de trabalho de estudantes de uma escola para pessoas com deficiência de Juazeiro, BA. A metodologia é de víeis qualitativo, a partir de um estudo de caso, com coleta de dados realizadas por meio de observação participante e entrevistas com roteiro semiestruturado − com a direção, professores e estudantes. Entre os resultados destaca-se: (1) que apesar do avanço na legislação e do incentivo à capacitação, a inclusão no mercado de pessoas com deficiência ainda é tímida; (2) a formação inicial em LIBRAS tem uma boa aceitação e é reconhecida com um diferencial; e (3) a cidadania plena do surdo somente será possível quando o mercado também estiver receptivo. Por tudo, é possível concluir que a formação em LIBRAS favorece a aceitação das pessoas com deficiência e aproxima o mercado de trabalho das pessoas surdas.
Peranan Komisi Pengawas Persaingan Usaha dalam Kegiatan yang Dilarang dalam Wujud Predatory Pricing Sektor E-Commerce
Authors: Jonathan Julius
Published: May 2023

Abstract
In globalization, modernization has occurred all aspects including economic field with emergence of e-commerce platforms to facilitate trade. In e-commerce sector, there is practice of flash sales are suspected form of predatory pricing. In addition, business competition in e-commerce sector must be supervised by KPPU because it has opportunity for unfair business competition to occur easily and technical aspects of business competition are different from conventional. The purpose of preparing this article to analyze alleged practice of flash sales as predatory pricing and analyze role of KPPU in supervising business competition in e-commerce sector. The research methodology uses normative juridical methods. The results, practice of flash sales cannot be stated directly as form of predatory pricing so that it uses a rule of reason approach and KPPU's role in supervising business competition in e-commerce must supported by adjustments to statutory regulations and KPPU can supervise business competition in e-commerce sector. 
Keywords: e-commerce; unfair business competition; predatory pricing; KPPU
 
Abstrak 
Pada era globalisasi, terjadi modernisasi pada seluruh aspek kehidupan manusia termasuk pada bidang ekonomi dengan timbul platform e-commerce untuk mempermudah perdagangan. Pada bidang e-commerce, terdapat praktik flash sale dan diduga merupakan bentuk predatory pricing. Selain itu, persaingan usaha pada sektor e-commerce harus diawasi oleh KPPU karena berpeluang terjadinya persaingan usaha tidak sehat dengan mudah dan teknis persaingan usaha memiliki perbedaan dari konvensional. Oleh karena itu, tujuan penyusunan artikel ini adalah menganalisa dugaan praktik flash sale sebagai predatory pricing terhadap ketentuan Undang-undang Nomor 5 tahun 1999 dan menganalisa terkait peran KPPU dalam mengawasi persaingan usaha di sektor ecommerce. Metodologi penelitian menggunakan metode yuridis normatif. Hasil dari penelitian ini adalah praktik flash sale tidak dapat dinyatakan secara langsung merupakan bentuk predatory pricing sehingga menggunakan pendekatan rule of reason dan peran KPPU dalam mengawasi persaingan usaha pada e-commerce harus didukung penyesuaian regulasi peraturan perundang-undangan sehingga KPPU dapat mengawasi persaingan usaha pada sektor e-commerce.
Kata Kunci: e-commerce; persaingan usaha tidak sehat; predatory pricing; flash sale; KPPU
Parental Triangulation in Separated & Divorced Families: Causes and Impact on the Intergenerational Parent-Child Conflict
Authors: Salerno Alessandra , Raciti Iolanda , Tosto Monica , Merenda Aluette
Published: May 2023

The triangulation process represents a violation of the boundary between parental and child relational subsystems which, in turn, affects family dynamics and relationships. The paper, with distinct reference to marital conflict and divorced couples, describes the main causes of the triangulation process and its impact on children (and adolescents) as significant third participants within the parental conflict. Besides, it fo-cuses on long-term consequences associated with triangulation process to parental conflict exposure, that can adversely affect the well-being of children during their life-cycle, and even into adulthood. A data-search was carried out for articles to be included in the review and articles were retrieved from different electronic databases (first: Scopus and Web of Science, then: PsychINFO, Google Scholar, EBSCO and ScienceDirect,). After having initially considered 152 articles, 58 studies were selected for this research. A qualitative analysis was conducted on selected studies, focusing on: (1) different types of triangulation commonly used in intergenerational family relationships; (2) an updated summary of the research around the impact of triangulation on the well-being of children and the parent-child conflict; and (3) the main characteristics of successful intervention of preventative and psychotherapeutic treatments. In conclusion, the results, examining the long-term effects of the triangulation process, highlight the developmental paths of children that are more exposed and at risk, and focuses on the importance of preventing the intergenerational transmission of marital conflict, as a way to reduce mental health costs and to improve the well-being of children and families who are all involved in these conflicting and destructive dynamics.
Lessons from a 3-Year Review of PSMA PET-CT in a Tertiary Setting: Can We Fine Tune Referral Criteria by Identifying Factors Predicting Positivity and Negativity?
Authors: Pant Vineet , Vinjamuri Sobhan , Zanial Ahmad zaid , Naeem Faisal
Published: May 2023

Aim of the study: To draw inferences from a retrospective evaluation of PSMA PET CT scans performed for the evaluation of biochemical recurrence.
Material and Methods: Retrospective analysis of 295 PSMA PET CT scans spanning 3 years between 2020 and 2022 was undertaken.
Results: Of 295 PET CT scans, 179 were positive, 66 negative and 50 had indeterminate findings. In positive group, 67 had radical prostatectomy and PSMA avid lesions were seen most commonly in pelvic lymph nodes. Remaining 112 positive scans, in non-radical prostatectomy group; 25 had recurrence only in prostate, 17 had recurrence involving prostate bed; 28 had no recurrence in prostate gland, while 42 had recurrence in prostate as well as extra prostatic sites. Overall, in non-prostatectomy group, 75 % population was harbouring a PSMA avid lesion in prostate gland while in remaining 25% population recurrence did not involve prostate gland. Majority of indeterminate findings were seen in small pelvic or retroperitoneal lymph nodes or skeletal regions (ribs/others) and in 9 patients indeterminate focus was seen in the prostate bed only. Follow up PSMA PET CT was helpful in prior indeterminate findings and unexplained PSA rise.
Conclusion: A higher recurrence in prostate bed while evaluating biochemical recurrence prompts us to think; whether prostatectomy should be offered more proactively? Follow up PSMA PET CT is helpful for indeterminate findings; a PSA rise of 0.7 ng/ml in 6 months can result in positive PSMA PET CT while negative scan can be seen upto 2ng/ml PSA rise in 6 months.
Analysis of Skull Anatomy for 3D Cephalometry – Normative Data Reveal Four Different Skull Types
Authors: Ludwigs Leon , Pape Christian , Visse Helena Sophie , Runte Christoph , Meyer Ulrich , Dirksen Dieter
Published: May 2023

The unsolved problem in three-dimensional surgical planning for patients with facial deformity, dysgnathia, or asymmetry is the lack of a normative database of “norm skulls” that can be used as treatment objectives. A study was conducted on 90 Eurasian persons (46 male and 44 female adults) with normal and balanced facial appearance, skeletal Class I pattern, and proper interincisal relationship with normal occlusion. Cone-beam computed tomography was performed. 18 landmarks were digitized and 3D cephalometric measurements of overall facial features, skull, midface and mandible were performed and analyzed by means of proportions calculated from the landmarks. Male and female skulls were analyzed as well as subdivisions revealed by cluster analysis. The data showed that four subtypes of skulls were distinguishable with statistical significance (p< 0,05). A male and a female type subdivided in a brachiocephalic and dolichocephalic phenotype could be identified. For each type then a mean shape was calculated by a Procrustes transformation, which in turn was used to create four template skulls from a male and a female skull by means of a thin plate spline transformation. The normative data of the subtypes can individually serve as a guide for orthodontic surgery, especially helpful in 3D plan-ning and execution of craniofacial operations.
Relationship of Force-Velocity Profile Between Field Sprints and Lab Ballistic or Cycling Ergometer on Wheelchair Basketball Players.
Authors: Brassart Florian , Faupin Arnaud , Hays Arnaud , Watelain Eric , Weissland Thierry
Published: May 2023

The upper limb force-velocity relationship (FVR) is a crucial aspect of athletic performance, par-ticularly in para sports where upper limb movements play a leading role in activities such as wheelchair propulsion. Athletes’ mechanical capacities can be evaluated on the field or in lab conditions. However, no studies have indicated a relationship between ergometers and field FVR or performances. Understanding para-athletes’ upper limb FVR can provide important insights for developing effective training programs and improving athletic performance in wheelchair bas-ketball players. Twenty-three wheelchair basketball players (12 women and 11 men) from French national teams performed a battery of three tests consisting of a 20 m sprint (SP) with Inertial measurement units (IMU) on wheels, a horizontal upper limb push-offs on a frictionless sled with two Kistler force plates (HBP), and a crank ergometer sprints test (CES) derived from arm er-gometer sprints using Brachumera, Lode. For the SP test, the FVR was computed with an estimation of force from the acceleration, the rolling resistance, and an estimation of the air resistance. Correlations between each variable measured were computed via Pearson correlations in R, as-suming strong relationships for r=0.7-1.0, moderate when r=0.40-0.69, and weak relationship when r<0.1-0.39. Significant differences were assumed when p<0.05. Strong correlations were found between the results of three tests conducted. The correlation coefficient between maximal theo-retical force (F0) data ranged from 0.85 to 0.88 and that between maximal theoretical power (P0) data ranged from 0.87 to 0.94. However, for maximal theoretical velocity (V0) data, the correlations between the three tests were less important. The performance variables showed a strong corre-lation with power measured on the HBP test without load. There is a significant relationship between HBP, CES, and SP variables. There is a correlation between performances on the three tests in our population, especially for the power. However, the V0 value of HBP was not representative of any performances. This work can show multiple protocols to assess para-athletes’ performances and show that upper limb symmetry depends on the gesture of the task and personal sports’ wheelchairs.
Investigation of the Gold Nanoparticles Synthesis, Mechanism and Characterization Using the Turkevich Method
Authors: Pereira Arnaldo César , Oliveira Ana E.F. , Resende Mayra A. C. , Ferreira Lucas Franco
Published: May 2023

The gold nanoparticle (AuNP) was synthesized using the well-known Turkevich method. This article explains didactic step-by-step of the synthesis, showing pictures of the entire process, including a well-explained mechanism and characterization study. The synthesis includes the reduction of NaAuCl4 using sodium citrate in high temperature (around 90 ⁰C). The two main mechanisms used to explain the AuNP synthesis via Turkevich method were explained. The first mechanism considerate that a nanowire intermediary and the other proposed that aggregate intermediates are not formed at any time during the synthesis. The materials (NaAuCl4 and AuNP) were characterized by UV-Vis, SEM, AFM, XRD and DLS. The UV-Vis exhibit an absorption maximum in 521 nm because the surface plasmon resonance (SPR) absorption band of AuNP. The SEM images of NaAuCl4 presents crystals with cubic shapes, while the AuNP presents average particle size of about 16-25 nm and particles that appear mainly spherical. To confirm the particles shapes, the AFM was conducted and it was possible to observe clearly the individual spherical nanoparticles. The XRD of AuNP showed the four main characteristic peaks for silver corresponding to (111), (200), (220) and (311) planes, confirming the cubic (FCC) silver. The DLS presented the average particle size of 3.3 ± 0.9 nm and the polydispersity index (PDI) of 0.574. In summary, the AuNP was synthesized using a simple and fast method. The result was a spherical and ultrasmall particle, that can be used is several applications.
Autologous Transplantation May Still Effectively Treat Relapsed Diffuse Large B-cell Lymphoma in Selected Patients
Authors: Bicsko Reka Rahel , Antal Lili , Magyari Ferenc , Szász Róbert , Udvardy Miklós , Illes Arpad , Gergely Lajos
Published: May 2023

Treating relapsed and refractory diffuse large B-cell lymphoma is still challenging for clinicians, but the available CAR-T and bispecific antibodies revolutionized therapy. Autologous stem cell transplantation was the most effective treatment modality previously. The authors report data from a single center over ten years. The retrospective study included 116 patients. There were 53 relapsed, 39 primary refractory cases, 19 had CNS involvement, and 5 received primary consolidation transplants. The median duration of follow-up was 46 months. The median event-free survival was 75 months, and the median overall survival was 105 months for all cases. Five-year overall survival was 59%, and event-free survival was 54%. Pretreatment prognostic factors at diagnosis had no effect on the outcome of transplantation. The authors found no difference between survival in relapsed or refractory cases, and the number of salvage lines or the germinal center / activated B-cell type also did not influence the results. Complete metabolic response before transplant confirmed by 18FDG PET/CT strongly affected survival. The pretransplant creatinine and CRP levels significantly influenced the long-term outcome. The number of stem cells infused did not affect survival, but engraftment within nine days did result in better survival. These data support the finding that the response to salvage therapy did select a better prognostic group who may still benefit from autologous transplantation.
Nanobiotics and the One Health Approach: Boosting the Fight against Antimicrobial Resistance at the Nanoscale
Authors: K Himanshu , Mukherjee Riya , Vidic Jasmina , Leal Elcio , da Costa Antonio Charlys , Prudencio Carlos , Raj V. Samuel , Pandey Ramendra , Chang Chung-Ming
Published: May 2023

Antimicrobial resistance (AMR) is a growing public health concern worldwide, and it poses a significant threat to human, animal, and environmental health. The overuse and misuse of antibiotics have contributed significantly to the emergence and spread of antimicrobial resistance, which may lead to significant economic consequences like reduced productivity and increased healthcare costs. Nanotechnology offers a promising platform for addressing this challenge. Nanoparticles have unique properties that make them highly effective in combating bacterial infections by inhibiting the growth and survival of multidrug-resistant bacteria in three areas of health: human, animal, and environmental. To conduct an economic evaluation of surveillance in this context, it is crucial to have a comprehension of the connections to be addressed by several nations by implementing national action policies based on the One Health strategy. This review provides an overview of the progress made thus far and presents potential future directions to optimize the impact of nanobiotics on AMR.
The Anti-Inflammatory Effects of Cannabis Sativa Extracts on LPS-Induced Cytokines Release in Immune and Non-Immune Cells in Vitro
Authors: Zaiachuk Mariia , Suryavanshi Santosh V , Pryimak Nazar , Kovalchuk Igor , Kovalchuk Olga
Published: May 2023

Inflammation is the response of the innate immune system to any type of injury. Although acute inflammation is critical for survival, dysregulation of innate immune response leads to chronic in-flammation. Many synthetic anti-inflammatory drugs have side effects, and thus, natural an-ti-inflammatory compounds are still needed. Cannabis sativa L. may provide a good source of in-flammation-reducing molecules. Here, we tested the anti-inflammatory properties of cannabis ex-tracts and pure cannabinoids in lipopolysaccharide (LPS)-induced inflammation in human THP-1 macrophages. We found that pre-treatment with cannabidiol (CBD), delta-9-tetrahydrocannabinol (THC), or extracts containing high levels of CBD or THC reduce the level of induction of various cytokines. The CBD was more efficient than THC, and the extracts were more efficient than pure cannabinoids. Finally, IL-6, IL-10 and monocyte chemoattractant protein-1 (MCP-1) were most sensitive to pre-treatments with CBD and THC, while IL-1β, IL-8 and TNF-α were less responsive. Thus, our work demonstrates the potential of use of cannabinoids or/and cannabis extracts for the reduction of inflammation and establishes IL-6 and MCP-1 as the sensitive markers for the analysis of the effect of cannabinoids on inflammation in macrophages.
Crop Prediction Model using Machine Learning Algorithms
Authors: Elbasi Ersin , ZAKI Chamseddine , Topcu Ahmet E. , Abdelbaki Wiem , Zreikat Aymen I , Cina Elda , Shdefat Ahmed Younes , Saker Louai
Published: May 2023

This research investigates the potential benefits of integrating machine learning algorithms and IoT sensors in modern agriculture. The focus is on optimizing crop production and reducing waste through informed decisions about planting, watering, and harvesting crops. The paper discusses the current state of machine learning and IoT in agriculture, highlighting key challenges and opportunities. It also presents experimental results that demonstrate the impact of changing labels on the accuracy of data analysis algorithms. The findings recommend that by analyzing wide-ranging data collected from farms, including real-time data from IoT sensors, farmers can make more informed verdicts about factors that affect crop growth. Eventually, the integration of these technologies can transform modern agriculture by increasing crop yields while minimizing waste. In our studies, we achieve a classification accuracy of 99.59% using the Bayes Net algorithm and 99. 46% using Naïve Bayes Classifier, and Hoeffding Tree algorithms. Our results indicate that we achieved high accuracy results in our experiments in order to increase crop growth.
Acute Effects of Blood Flow Restriction Training on Movement Velocity and Neuromuscular Signal During the Back Squat Exercise
Authors: SILLERO MANUEL GARCÍA , Maroto-Izquierdo Sergio , Galvan-Garcia Maria , Benitez-Porres Javier , Vargas-Molina Salvador , Jurado-Castro Jose Manuel
Published: May 2023

The aim of this study was to verify the effects of blood flow restriction on movement velocity and muscle activity during the back-squat exercise. Methods: Twenty-four university students participated in this study. In two randomized 72-hours apart sessions, participants performed a 4-set protocol consisting of 30-15-15-15 repetitions performed at 30% of their one-repetition maximum in the back-squat exercise. In both sessions, neuromuscular function was monitored by surface electromyography (EMG) and movement velocity (mean propulsive velocity [MPV], peak concentric velocity [Vmax] and the effort index [EI]). Blood flow restriction (BFR) was applied during exercise in one of the experimental sessions with 80% of full arterial occlusion pressure over lower limbs. Results: BFR condition showed higher (p<0.05) EI, peak and rooted mean square normalized EMG in set 1 compared to set 2. Similar MPV and Vmax were observed at each set for both BFR and control conditions. No significant differences were observed between conditions at any set. Conclusions: BFR did not imply changes in neuromuscular performance during low-intensity resistance training, but it might induce greater intra-series velocity loss and less activation of the muscles involved.
Hierarchical Model-Based Deep Reinforcement Learning For Single-Asset Trading
Authors: Millea Adrian
Published: May 2023

We present a hierarchical reinforcement learning (RL) architecture that employs various low-level agents to act in the trading environment, i.e. the market. The highest level agent selects among a group of specialised agents, and then the selected agent decides when to sell or buy a single asset for some period. This period can be variable according to a termination function. We hypothesized that due to different market regimes, more than one single agent is needed when trying to learn from such heterogeneous data, and instead, multiple agents will perform better, with each one specialising in a subset of the data. We use $k-means$ clustering to partition the data and train each agent with a different cluster. Partitioning the input data also helps model-based RL (MBRL), where models can be heterogeneous. We also add two simple decision-making models to the set of low-level agents, diversifying the pool of available agents and thus increasing overall behaviour flexibility. We perform multiple experiments showing the strengths of a hierarchical approach and test various prediction models at both levels. We also use a risk-based reward at the high level, which transforms the overall problem into a risk-return optimization. This type of reward shows a significant reduction in risk while minimally reducing profits. Overall, the hierarchical approach shows significant promise, especially when the pool of low-level agents is highly diverse.
Evolution of Collective Sars-Cov-2 Humoral Immunity among the Population of the Republic of Belarus
Authors: Popova Anna Y. , Smirnov Viacheslav , Egorova Svetlana A. , Tarasenko Alexander A. , Dashkevich Alla M. , Milichkima Angelika M. , Scuranovich Angela L. , Drozd Irina V. , Glinskaya Iruna N. , Zueva Elena V. , Samoilovich Elena O. , Ivanov Valery A. , Ramsay Edward S. , Gubanova Alexandra V. , Drobyshevskaya Victoria G. , Zhumbaeva Oyuna B. , Petrova Olga A. , Razumovskaya Alexandra P. , Karaban Inna A. , Amvrosieva Tamara V. , Shmeleva Natalya P. , Rubanic Ludmila V. , Dronina Alina M. , Totolian Areg A.
Published: May 2023

Background. The course of the COVID-19 epidemic process depends on population immunity which prevents pathogen spread among the population. Aim: to study the evolution of SARS-CoV-2 humoral immunity in the Belarusian population relative to COVID-19 pandemic dynamics. Materials and methods. The work was carried out according to a methodology for assessing population immunity developed by Rospotrebnadzor (Russia) and the Belarusian Ministry of Health with the participation of the St. Petersburg Pasteur Institute (SPPI), taking into account WHO recommendations. The study was approved by the Bioethics Committee of Belarus and the SPPI Bioethics Committee. Participant selection was carried out by questionnaire using a cloud (internet server) service. To monitor population immunity, a cohort of 4,661 people (participating in all stages of seromonitoring) was formed from the overall volunteer group. Volunteers were randomized by age group (1-17, 18-29, 30-39, 40-49, 50-59, 60-69, 70+ years), region, and professional group. For the detection of antibodies (Abs) to nucleocapsid (Nc) and S glycoprotein receptor-binding domain (RBD), corresponding assay systems were used following manufacturer instructions. The study was conducted in 4 stages according to a single scheme. Results. In the 1st stage (pandemic month 15), collective immunity was due mainly to Nc+RBD+ Ab status alone. By the 2nd stage (carried out after 4 months), their share decreased 1.2-fold, while the share of volunteers who had only RBD Abs increased 1.7-fold. In the 3rd and 4th stages (carried out after 9 and 19 months), the share of persons with RBD+Nc‒ compared to the 2nd stage decreased by 3.5%; the proportion of persons with Nc+RBD‒ Abs increased by 1.5-fold. The most important factor in population immunity was vaccination of the population, the coverage of which reached 70% by the 4th stage. Among vaccines, the Sputnik V and Sputnik Light vector designs were used most often. The whole-virion, inactivated BIBP-CorV vaccine was used less often. Conclusion. The evolution of collective SARS-CoV-2 humoral immunity included a set of changes in circulating Ab levels (Nc, RBD). The hybrid immunity formed helped to reduce the incidence to nearly zero.
Javaslatok a szövegértés tantárgyakba ágyazott fejlesztéséhez – az olvasási stratégiák tanítása I.
Authors: Tary Blanka , Fejes József Balázs , Hódi Ágnes , Szenczi-Velkey Beáta , Vígh Tibor
Published: May 2023

Jelen munka célja a szövegértés-fejlesztés egy, a hazai iskolai gyakorlatban kevéssé ismert és alkalmazott lehetőségének, az olvasási stratégiák tanításának a bemutatása annak érdekében, hogy iránymutatásul szolgáljon az osztálytermi gyakorlatokhoz. A tanulmány röviden definiálja az olvasási stratégiákat, elemzi a tanítási helyzetüket, bemutatja a szövegtípusok, -formák és az olvasási stratégiák közötti kapcsolatokat, és kitér tanításuk jelentőségére is. Ismerteti a szövegtípusok és a stratégiák kapcsolatát, hiszen az olvasási stratégiák alkalmazása különböző szövegek esetében eltérő lehet. Ezt követően – példákkal szemléltetve, elsősorban gyakorlati vonatkozásban – bemutatja a leggyakoribb olvasási stratégiákat. Végül javaslatokat fogalmaz meg az olvasási stratégiák tanítását illetően. A cikkben ismertetett olvasási stratégiák elsősorban nyomtatott szövegekhez kapcsolódnak, de jelentős részük digitális szövegek olvasásakor is hasznosítható lehet.
A tanári beszéd fatikus nyelvi elemei az osztálytermi diskurzusban
Authors: Asztalos Anikó
Published: May 2023

A tanulmány témája a fatikus nyelvi elemek vizsgálata a tanári beszédben. A fatikus funkció a nyelv eredendő, elsődleges funkciója, az osztálytermi diskurzusokban a tanár és a diákok közötti kapcsolat létrehozásához, fenntartásához és lezárásához járul hozzá. Az ismertetett kutatás célja a tanárok beszédfordulóiban lévő verbális fatikus elemek típusainak a megfigyelése. A tanulmány 12 magyar nyelvi tanóra videós anyagának annotálása és szegmentálása alapján mutatja be az osztálytermi diskurzus általános jellemzőit, emellett differenciálja a fatikus nyelvi elemek fajtáit a tanárok beszédében. A nyelvi példák alátámasztják, hogy a fatikus nyelvi elemek az osztálytermi diskurzusban minden tanári megnyilatkozástípushoz kapcsolódnak, megfigyelhetők a tanári értékelésben, a kérdésben és a magyarázatban is. A fatikus nyelvi elemek megjelenésében egyéni beszédrituálék, szokásszerű mintázatok azonosíthatók. A vizsgálatban feltárt eredmények mind a gyakorló pedagógusok, mind az osztálytermi diskurzust kutatók számára hasznos adalékul szolgálhatnak a további elemzésekhez.
Kontaktushatások vizsgálata a kárpátaljai diákok nyelvhasználatában
Authors: Váradi Krisztián
Published: May 2023

A tanulmány kárpátaljai főiskolai és egyetemi hallgatók, valamint különböző szakképzési intézményekben tanuló diákok nyelvhasználati szokásait mutatja be. A kárpátaljai magyarok mindennapi nyelvhasználatában gyakran előfordulnak szláv nyelvekből átvett kölcsönszók, hiszen az ukrán államnyelv és az orosz nyelv hatással van a helyi kisebbségek anyanyelvére, jelen esetben a magyar nyelvre is. A tanulmány azt vizsgálja meg, hogy a kárpátaljai diákok milyen mértékben ismerik a szláv kölcsönszók jelentését. Összesen 63 adatközlő oldott meg különböző feladatokat egy kérdőíves felmérés során (képleírás, kölcsönszók helyettesítése magyar nyelvi elemekkel, többszöri választás, szómeghatározás definíció alapján, kölcsönszók felsorolása). Az eredmények azt mutatják, hogy a kárpátaljai fiatalok többségében ismerik a szláv lexikai kölcsönelemek jelentését, anyanyelvi dominanciájuk hatására azonban a magyar nyelvi megfelelőket részesítik előnyben. Ez alól kivételt egyedül a kultúraspecifikus kifejezések jelentenek.
Az Okos Doboz digitális feladatbank „Kárpát-medence – Külhoni régiók” digitális feladatgyűjteményének szerepe az anyanyelvi nevelésben
Authors: Lénárd András
Published: May 2023

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An Analysis Of Leading And Potential Sectors In The Development Of Archipelagic Areas (A Case Study in East Seram Regency, Maluku)
Authors: Rumau Untung F , Hahury Hendri D , Tutupoho Ali , Louhenapessy Fredy H , Saptenno Fibryano
Published: May 2023

This study aims to understand leading and potential sectors in the development of archipelagic area. This study used time-series data obtained from Statistics Indonesia in the form of Gross Regional Domestic Product (GRDP) of East Seram Regency, Maluku Province with location quotient and shift share at the analysis tools. The results show that East Seram Regency has 4 basic sectors – including agricultural, forestry and fisheries; mining and quarrying; real estate; and health service and social activity – in addition to 13 non basic sectors. Meanwhile, the economic sectors which have the potential to grow faster and are specialized include the agriculture, forestry and fisheries; mining and quarrying; processing industry, electricity and gas supply; water supply, sewerage, waste and recycling management; construction; wholesale and retail trade, and car and motorcycle repairs; provision of accommodation and food and beverages; information and communication; financial and insurance service; real estate; corporate service; public administration, and defense and compulsory social security; education service; health service and social activity; and other services. Further, the differential shift components which are found to be positive and growing faster compared to the GRDP of Maluku Province consist of the agriculture, forestry and fisheries; wholesale and retail trade, and car and motorcycle repairs; transportation and warehousing; provision of accommodation and food and beverages; financial and insurance service; and real estate. Furthermore, the development pattern in East Seram Regency still adopts the development pattern in continental areas as evidenced by the economic sectors in the marine and waters whose potential have not been fully utilized.
Analysis of Marketing Strategy in Achieving Banking Goals at PT Bank Xyz
Authors: Mustajab Duta
Published: May 2023

This study aims to determine the marketing strategy that has run the company and to determine the relationship marketing strategy through SWOT analysis carried out by the company in relation to the achievement of corporate goals.

While the methods of analysis used in this study is an analysis of SWOT analysis is to mngetahui strengths and weaknesses and the opportunities and threats faced by the Bank in the implementation of marketing strategies.

Based on the results of the study showed that based on the evaluation of the implementation of the marketing strategy implementation SWOT banking services , especially in the company of PT. Bank Mandiri Branch Makassar, which indicates that the marketing strategies undertaken so far in the marketing of banking services has been able to minimize weaknesses and threats in implementing strategies that have been carried out and in addition the power and opportunities are more prominent when compared to the weaknesses and threats. Based on the results of the SWOT analysis , the strategy is suitable for use in the marketing of banking services at PT. Bank Mandiri Branch Makassar is an aggressive strategy.
The Power of Digital Tools Leveraged for Excellence in Operation Planning
Authors: Gupta N. , Moraes W. Oda de Oliveira , Vieira C. , Khelil R.
Published: May 2023

The oil and gas (O&G) business is going through a natural but accelerated evolution to incorporate more digital tools into its business model. While it is important to adapt quickly, under such circumstances it is equally important to plan with the future in mind. The biggest challenge the oil and gas industry has faced recently is the sudden shifts in demand and supply. The pandemic era curbed demand, while the recovery resulted in an unprecedented supply shortage. This imbalance identified an opportunity to quickly evolve new sales and operational planning (S&OP) processes. These processes were designed to continually balance supply and demand at different time horizons. The digital capabilities were further empowered to harness S&OP potential to forecast and plan better than ever before. The digital planning tool (DPT) is now part of the business fabric, enabling product forecasting up to 12 months out. This paper illustrates one of the steps in the technological digital journey driven by O&G service companies. It shows how implementing a DPT enables S&OP processes to optimize resource management. Such optimization creates a more agile and accurate response to a fluctuating demand-supply balance, improving company performance overall.
Citizen Developers – KIPIC Case Study: Empowering Innovation and Accelerating Digital Transformation
Authors: Alfedaghi Hadla S.
Published: May 2023

The oil and gas industry face unprecedented challenges and opportunities which demand innovative solutions. There needs to be more than the traditional centralized IT operational model to meet the dynamic needs of the industry. This has led to new models, such as the citizen developer program, which enables business users to create and deploy applications without requiring specialized technical skills.

The citizen developer program is a new approach allowing non-IT professionals to create applications for their business needs using low-code and no-code platforms. This program aims to decentralize IT operations, increase innovation, reduce costs, and enhance customer experience. The democratization of technology is the core concept behind the citizen developer program, which enables businesses to create their applications and automate their processes [1].

The implementation of a citizen developer program requires careful planning and consideration of various factors, including change management, awareness and marketing of the concept, training, selecting the correct low code no code tool, management buy-in, building a community of practices for citizen developers, governance/policy, and more. These elements are critical to the program's success and must be carefully considered during implementation.

This manuscript provides a framework for implementing a citizen developer program in the oil and gas industry. It also includes a case study of implementing such a program and creating significant value in Kuwait Integrated Petroleum Industries Company (KIPIC). The Framework emphasizes the importance of change management, awareness and marketing of the concept, training, selecting the correct low code no code tool, management buy-in, building a community of practices for citizen developers, governance/policy, and more. The manuscript aims to provide insights into the benefits of implementing a citizen developer program in the oil and gas industry and its potential impact on the IT operational model.

In summary, the citizen developer program represents a paradigm shift in the oil and gas industry, which enables businesses to create and deploy applications without relying solely on IT professionals. This program can increase innovation, reduce costs, and enhance customer experience. The implementation of a citizen developer program requires careful planning and consideration of various factors, as outlined in this manuscript.
Sustainable Water Management Solution for Drilling Fluids Wastes
Authors: Hamdan Tariq , Al Nuaimi Mouza , Arena Carmelo , Kostic Tijana
Published: May 2023

Scarcity of water resources in UAE and affording a nonstop water supply for drilling operation was always a concern.

The main objective of availing a fit for purpose solution was: Saving the underground water resources.Cost optimization:Saving the cost of Haulage transportation. (30-50%)Save the Total Value of waste disposal injection package.Saving the cost of salt as the treatment technologies is designed to save the salt content.HSE advantage by reducing the Transportation requirements.Simple to implement in all ADNOC rigs fleetNot affect the rig operation.

Dewatering of the waste drilling fluid It is the most common and promising treatment technology. Dewatering It is the most common and promising drilling fluids waste treatment technology, this technology depends on 2 simple Mechanisms which is Coagulation and Flocculation (chemical treatment) –Coagulation is the water treatment process that causes very small, suspended particles to attract one another and form larger particles.–Flocculation is the water treatment process where the coagulated particles (pinpoint flocs) bridge together resulting in larger, more shear resistant structures that settle faster with less carryover of solid particles into the separated water.