bluuebunny/crossref_metadata_2025 huggingface dataset:
INTEGRAÇÃO SENSORIAL E PROTOCOLOS DE AVALIAÇÃO: UMA REVISÃO DE LITERATURA
Authors: Prazeres Larissa Santos , Rodrigues Mara Camila , Torres Raphaela Fonseca , Oliveira Suelen Pereira Santos , Cunha Suelen Diane Pantoja da , Costa Samara de Araújo , Montenegro Karina Saunders
Published: January 2023

Tradicionalmente, o Terapeuta Ocupacional atua para promover
a independência e autonomia de sujeitos que apresentam dificuldades
para exercer seus papéis ocupacionais na sociedade, seja por demandas
físicas, sensoriais, mentais e/ou sociais, podendo participar de equipes
de saúde, educação e na área social (BARROS et al., 2002 apud
CARVALHO, 2012).
De acordo com o Artigo 4, do Código de Ética de Terapia
Ocupacional, este profissional compõe equipes de promoção,
prevenção de agravos, tratamento, reabilitação e cuidados paliativos.
Além de estabelecer diagnósticos na área, realizar avaliação e
acompanhamento do desempenho ocupacional de sujeitos
individualmente ou em grupos, sem qualquer tipo de discriminação e
seguindo os princípios do sistema de saúde e de assistência vigentes no
Brasil (BRASIL, 2013).
O USO DA ABORDAGEM DE INTEGRAÇÃO SENSORIAL DE AYRES POR TERAPEUTAS OCUPACIONAIS NO TRATAMENTO DE CRIANÇAS COM SELETIVIDADE ALIMENTAR: UMA REVISÃO INTEGRATIVA DE LITERATURA
Authors: Moura Bárbara , Barbosa Anne Clei de Amaral , Nascimento Eliane Santos Silva , Khalek Maíza de Brito Barbosa Abdul , Cortez Michele Rizzi , Silva Thaiane Sena e , Costa Maria de Fátima Góes da
Published: January 2023

A Integração Sensorial é compreendida como um processo
neurofisiológico, que busca identificar a função do sistema nervoso
central em ordenar, interpretar, processar e modular as informações
provenientes dos sistemas sensoriais. Os sistemas sensoriais são os
seguintes: visual, olfativo, gustativo, tátil, auditivo, vestibular e
proprioceptivo, todos relacionados diretamente à aprendizagem e a
memórias anteriores consolidadas no cérebro (SILVA et al., 2021).
INFLUÊNCIA DA INTEGRAÇÃO SENSORIAL NO DESEMPENHO MOTOR DA CRIANÇA COM TRANSTORNO DO ESPECTRO AUTISTA
Authors: Serra Ana Paula Penha , Alves Eduarda Mendes Costa , Nunes Emanuela Ramos , Cabral Joseane Muniz , Moraes Bárbara Letícia Costa de
Published: January 2023

O processo de Integração Sensorial foi definido por A. Jean
Ayres como: “[...] o processo neurológico que organiza a sensação do
próprio corpo e torna possível usar eficientemente no meio.”
É um processo inconsciente, pois acontece sem que
necessitemos pensar nele e é muito importante para todas
as formas de aprendizagem, seja ela acadêmica, de
competências para as atividades de vida diária e sociais,
ou mesmo a capacidade de ter empatia pelo outro. Aquilo
que vemos, cheiramos, saboreamos ou tocamos é
decifrado a cada momento na nossa experiência de viver.
(SERRANO, 2016, p. 32).
Pelatihan pemanfaatan aplikasi Kahoot! sebagai Assesment Edutainment bagi guru Sekolah Dasar
Authors:   Universitas Muria Kudus, Ardianti Sekar Dwi , Ulya Himmatul ,   Universitas Muria Kudus
Published: January 2023

Pandemi Covid-19 memberikan dampak penyesuaian pada semua sektor termasuk dalam sektor pendidikan di Indonesia. Untuk mengatasi hal tersebut Pemerintah Indonesia menerapkan pembelajaran secara daring dan luring. Akan tetapi ketidak siapan guru dalam menghadapi perubahan system berlajar tersebut menjadi salah satu kendala dalam pembelajaran daring, terutama penggunaan media pembelajaran digital. Sehingga perlu diadakan pendampingan pengembangan media pembelajaran dan asesment yang baik.Tujuan dari kegiatan pengabdian ini adalah memberikan pengetahuan kepada guru-guru di SD 2 Peganjaran mengenai pemanfaatan aplikasi Kahoot! sebagai sistem Assesment Edutainment. Metode yang digunakan dalam pengabdian ini adalah dengan memberikan pelatihan interaktif dan pendampingan. Selanjutnya, dalam proses pelatihan ada interaksi dua arah sehingga memberikan kesempatan kepada guru-guru di SD 2 Peganjaran sebagai peserta pelatihan untuk menyumbangkan ide, pendapat, pikiran, dan pengalamannya. Peserta pendampingan terdiri dari 12 guru dan 1 kepala sekolah. Pelaksanaan pendampingan pemanfaatan aplikasi Kahoot! sebagai sistem assesment edutainment pada guru di SD 2 Peganjaran dirancang dalam beberapa tahap, antara lain: perencanaan, pelaksanaan, follow up, dan evaluasi. Hasil dari kegiatan pengabdian ini adalah guru-guru di SD 2 Peganjaran mampu memanfaatkan Kahoot! sebagai sistem assesment edutainment. Hasil yang diperoleh dari kegiatan pengabdian yaitu guru di SD 2 Peganjaran sebanyak 84,6%mampu membuat instrumen dengan aplikasi Kahoot! sebagai sistem Assesment Edutainment pada pembelajaran daring. Pendampingan pemanfaatan aplikasi untuk penilaian pembelajaran secara daring memberikan pengetahuan dan keterampilan guru untuk memanfaatkan dan menyusun penilaian menggunakan aplikasi Kahoot! sebagai sistem Assesment Edutainment pada pembelajaran daring
Pemberdayaan masyarakat melalui pengolahan teh dan kopi beras khas Ketan Hitam di Desa Latellang Kabupaten Bone
Authors:   Universitas Muhammadiyah Bone, Asfar Andi Muhammad Irfan Taufan , Nur Syarif ,   Universitas Muhammadiyah Bone, Asfar Andi Muhamad Iqbal Akbar ,   Politeknik Negeri Ujung Pandang, Asfar Andi Hasryningsih ,   Universitas Muhammadiyah Bone, Nurannisa Andi ,   Universitas Muhammadiyah Bone, Sudartik Eka ,   Universitas Muhammadiyah Bone
Published: January 2023

Black glutinous rice is a potential commodity in Latellang Village. However, this potential is not empowered because there is no counseling or other service activities in processing black glutinous rice. The community, especially partners, namely the Maddaung Farmer Group, do not take full advantage of black glutinous rice and only process it into delicious snacks and served at certain times. Therefore, this community service aims to maximize the potential of black glutinous rice by diversifying processed black glutinous rice products into coffee and tea. This product has never existed or been introduced by extension workers or replicated other product innovations, especially in Bone Regency. Community empowerment through this community service program is carried out through three main stages: counseling, training, and mentoring. The results of the program implementation are that partners can find out information on the benefits of processing black glutinous rice and have skills in diversifying products into tea and coffee. In addition, partners have also been able to process finances and market products through the marketplace with an increase in productivity of 98%. The impact of this service can realize sustainable development goals, namely healthy and prosperous villages.
Pelatihan seni musik Tradisi Gamelan Tokol pada generasi muda
Authors:   Universitas Hamzanwadi, Murcahyanto Hary
Published: January 2023

Traditional music is one of the characteristics of an area that needs to be preserved. The traditional music of the Gamelan Tokol is starting to become less attractive to the younger generation due to the need for more socialization, training, and platforms for performing their works so that the younger generation's creativity in developing traditional music begins to wane. In addition, there is a need for the notation of traditional pieces that have never been written in notation form. This activity aims to realize conservation efforts, creativity, and regeneration of traditional Gamelan Tokol music. The mentoring activities will be carried out from May to July 2022 at the Tunggal Galih art studio, Denggen Village, Selong District. This activity was attended by 43 youth arts activists from areas around the Selong sub-district and assisted by ten students. The result of this activity is the existence of traditional Gamelan Tokol music training activities, contributing to the younger generation in terms of creativity in playing patterns using notation so that a new generation is formed, which is the previous regeneration as an embodiment of efforts to preserve traditional music in the younger generation.
Pelatihan peningkatan kemampuan komputer, internet dan aplikasi desa
Authors:   Universitas Islam Negeri Mataram, Ghazali Muhammad , Zohri Muhammad ,   Universitas Islam Negeri Mataram, Ramadhan Wahyu ,   Universitas Islam Negeri Mataram, Jamaluddin Jamaluddin ,   Universitas Hamzanwadi
Published: January 2023

Operating a computer as a data processor is needed in all fields. One of the fields that must master Information Technology, and Communication (ITC) skills is the field of government, from the central government to the village government. It is crucial to upgrade the capabilities of computers for village officials because, currently, all data is computerized. The purpose of this community service is to help improve the computer/laptop and internet skills of village staff, especially in Perampuan Village, Labuapi District, West Lombok Regency, NTB. The stages in this service are: analyzing service problems; second, preparing service material; third, carrying out service; and fourth, reporting or post-service activities. The results show increased participant ability on computers and the internet. The participants were enthusiastic about the training on making Google Drive, Google Docs, and Google Spreadsheets because this was the first training they had received. Because creating Google Drive, Google Docs, and Google Spreadsheets is necessary for village services, especially in an era when all residents have smartphones, and all data must now be cloud-based. The village head and the training participants hope the Mataram UIN lecturer service team will still be scheduled to carry out a community service program because the village really needs this service. The participants also suggested that they spend more time so that they are more flexible in the teaching and learning process
The interdisciplinary round-table discussion "Methodological linguoconceptology: exploring different perspectives"
Authors: Demidova N. I. , Bogdanova E. S.
Published: January 2023

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Algorithmic technology of mastering the lexical-semantic and grammatical norms of pronominal usage. Part 2. Enhancing school students’ speech culture while studying lexical-semantic and grammatical norms of pronominal usage
Authors: Sulnichenko V. N.
Published: January 2023

The second part of the paper considers the norms of using various lexical and grammatical categories of pronouns. Additionally, the research reveals their significance in promoting school students’ speech culture. Sixth-form students learn to differentiate between lexical-semantic and grammatical norms, use pronouns correctly in sentences as well as in texts, and examine them with the help of linguistic analysis and generalisation. This approach to learning pronouns encourages schoolchildren to evaluate speech in terms of correctness, to detect speech errors and correct them. The presented methodology for studying pronouns helps to engage schoolchildren in unsupervised research activity when proofreading texts with the aid of algorithms. It also increases the cognitive activity level in the classroom and forms speech culture.
The mystery of creativity in man and in nature: a linguostylistic analysis of M. M. Prishvin’s "failed novel" "Crane Homeland" (to the 150th anniversary of the birth)
Authors: Frolova E. A.
Published: January 2023

Based on a linguo-stylistic analysis of the story "Crane Homeland", the article attempts to reveal M. M. Prishvin’s concept of creative mastery origins. The research aims to examine those linguistic means of the writer’s "failed novel" which enabled M. M. Prishvin to unlock the "secrets" of creativity in man and in nature. To achieve this goal, I used lexical and word-formation analysis, comparative, and integrative methods. Additionally, contextual semantic analysis made it possible to identify the transformations of the meaning of individual linguistic units and reveal the philosophical component of this work of fiction in its entirety. The paper explores various linguo-stylistic devices which allowed the writer to reveal the essence of creativity. These include devices of comparison and contrast, repetition, si mile, semantic widening, playing with set phrases, polynomination, and others. The characterisation of the Claudophora algae nomination series permits establishing the intertextual connections of the work as well as determining the symbolic meaning of the text components. The paper concludes that M. M. Prishvin saw two sides of the creative process, namely the technical and the divine. One can learn the former and become a belletrist. The latter defies explanation and is a revelation from Heaven (a book... falls from the heavens).
Non-agreeing attributes in a sentence and a text
Authors: Devyatova N. M.
Published: January 2023

The article considers non-agreeing attributes in an oblique case modifying a noun that names a person (i. e. a person noun), an object, or space as well as their semantics, textual functions, and the problem of detachment. The aim is to show the dependence of the detachment problem on the text functions fulfilled by a non-agreeing attribute. As a rule, it is non-detached attributes which serve as a means of expressing the semantic category of definiteness. The category of definiteness/indefiniteness manifests itself as a textual category in this part of the language system. A non-agreeing attribute referring to a person is more often used when introducing new characters or a new view of them. Such text fragments are reproductive; they are usually organised by the observer’s point of view. A non-agreeing attribute can join a sequence of other attributes which it is connected with through different relationships such as clarifying, cause-effect, extending, and others. The problem of the number of attributes modifying a noun referring to a person is associated with the viewpoint issue, i. e. different extent of the observer’s interest in the depicted character. The important/unimportant (random) depicted character criterion turns out to be significant for describing non-agreeing attributes. Object and spatial nouns also function as indefinite in the context of non-agreeing attributes. Attributes modifying them name significant features of the object and convey the idea of definiteness.
The lexicographic legacy of Professor B. A. Larin and modern lexicography (to the 130th anniversary of the birth)
Authors: Generalova E. V.
Published: January 2023

The paper examines the lexicographic legacy left by Professor B. A. Larin (1893–1964). It also points out the direct correlation between Larin’s ideas and the controversial issues and moot points in modern lexicography. 

I provide a brief review of B. A. Larin’s biography and his philological interests. The conclusion underscores the significance of the lexicographic ideas in the linguist’s works as well as the versatility of his scientific interests. At the same time, they are united by such cross-cutting leitmotifs as a broad historical perspective, studying colloquial speech in its various manifestations, attention to semantics. B. A. Larin’s ideas that were far ahead of their time are identified as a result of comparing the concepts he developed and the directions of modern lexicography evolution. For example, one such idea is a complete dictionary. It directly correlates with the currently relevant project of a complex (universal) dictionary. Moreover, Larin raised the issues of combining linguistic and encyclopaedic information in a historical dictionary as well as of scientific illustration of historical dictionary entries, which are still unresolved. The ideas of bilingual author lexicography, onomastic author lexicography, and historical phraseology proposed by Larin have hardly been implemented yet. The paper emphasises that B. A. Larin is one of the founders of Russian historical lexicography. Also, he created such a type of historical dictionary as the thesaurus of one written monument and became the father of Russian sociolinguistics and comparative phraseology. He formulated principles for describing various aspects of vocabulary, proposed a number of innovative lexicographic projects, thus anticipating many modern lexicographic theories and developments.
Teachers’ Obstacles of Online Learning Process During Pandemic Era (A Study of English Teachers at Golden Kidz School, West Jakarta)
Authors: Isrofiah Nurul , Kusumadewi Hermariyanti
Published: January 2023

The objective in this research is that there are various obstacles in the implementation of online learning due to the impact of the COVID-19 pandemic experienced by Golden Kidz teachers, Jakarta. This research uses a descriptive case study design with a qualitative approach. In this research, the key instrument is the researcher. The data in this study are the obstacles faced and the source of interview data from subject teachers at the Golden Kidz School Jakarta, there are 3 people. They were selected as informants based on the problems experienced by the teacher during the implementation of online learning. Collecting data using interview techniques. To test the validity of the data, the researcher triangulated the time by comparing the results of the interviews. Based on data analysis, the results of the study indicate that there are several obstacles that become teacher problems during online learning at Golden Kidz School. These problems include (a) internet access, (b) technology literate, (c) lack of student interest in learning, (d) difficult communication, (e) limitation of teachers in preparing learning materials.
Pemanfaatan Media Interaktif Sebagai Pendukung Pembelajaran Daring di MTs Esa Nusa Islamic School
Authors: Mutia Intan , Cholifah Wahyu Nur , Yulianingsih Yulianingsih
Published: January 2023

Pembelajaran yang hanya mengutamakan buku sumber dan metode ceramah di ruang kelas saja memberikan kesan bahwa pembelajaran merupakan kegiatan yang kurang menarik dan kurang bermakna. Melihat kenyataan tersebut maka guru dituntut untuk mengembangkan model pembelajaran yang bisa melibatkan siswa secara aktif dalam kegiatan pembelajaran, apalagi dalam kondisi tidak dapat bertatap muka dengan siswa. Metode yang digunakan dengan kombinasi presentasi, diskusi dan pelatihan. Tujuan pengabdian masyarakat ini adalah peningkatan keterampilan guru dalam menyebarkan materi ajar yang sudah diolah melalui media interaktif Powerpoint dan grup WhatsApp. Hasil kegiatan berupa meningkatnya kemampuan guru dalam mengolah bahan ajar menggunakan fitur-fitur aplikasi Powerpoint agar lebih menarik dan interaktif serta mudah dimengerti siswa. Kegiatan ini direkomendasikan keberlanjutannya dengan materi-materi yang disesuaikan dengan kebutuhkan mitra dan penggunaan media interaktif lainnya.
Penerapan Literasi Digital Dalam Pembelajaran Siswa SMK Ki Hajar Dewantoro
Authors: Priambodo Caka Gatot , Setiawan Heri Satria
Published: January 2023

Literasi media dan digital kini mulai dibicarakan di masyarakat dan saling terkait satu sama lain. Literasi media lebih memfokuskan pada penafsiran pesan yang disampaikan melalui media dan cara kita menanggapi pesan tersebut, sedangkan kata digital berfokus pada akses informasi berbasis teknologi informasi dan komunikasi serta solusi mengakses informasi dan layanan internet yang mempermudah masyarakat dalam berbagai aktivitas. Penting bagi guru SMK untuk mengetahui bagaimana cara yang baik, aman, terkontrol dan bermanfaat dalam menggunakan aplikasi teknologi informasi berbasis Literasi Digital dalam pembelajaran bagi siswa. SMK Ki Hajar Dewantoro merupakan salah satu sekolah menengah kejuruan bidang studi keahlian bisnis dan manajemen, teknologi informasi dan komunikasi di kota Tangerang provinsi Banten. Guru-guru SMK Ki Hajar Dewantoro sudah tentu mengajarkan siswa belajar dengan menggunakan perangkat atau aplikasi program komputer maupun teknologi informasi dalam aktivitasnya di  kelas. Untuk menambah atau memperkaya pengetahuan guru-guru di SMK Ki Hajar Dewantoro maka tim pengabdian kepada masyarakat melalui dosen-dosen informatika Universitas Indraprasta PGRI mengadakan sosialisasi pengetahuan tentang Literasi Digital untuk menambah metode pembelajaran guru bagi siswa didik di sekolah. Sosialisasi ini dapat berdampak baik bagi guru dalam metode pembelajarannya yang bisa berdampak baik juga bagi siswa didiknya agar hasil yang ingin dicapai bersama terlaksana dengan optimal.
PERANCANGAN BASIS DATA HELPDESK SYSTEM PT XYZ MENGGUNAKAN MICROSOFT SQL SERVER 2019
Authors: Arif Sutan Mohammad , Purwoko Hendro
Published: January 2023

Helpdesk merupakan sistem yang bermanfaat memberikan pelayanan seperti: keluhan, informasi atau kendala teknis yang seluruh datanya dapat dijadikan tolok ukur keberhasilan pelayanan pada pelanggan dan atau karyawan internal. Data Helpdesk disimpan kedalam basis data berfungsi sebagai media penyimpanan dengan basis data Microsoft SQL Server 2019 menggunakan aplikasi SQL Server Management Studio (SSMS) Pengembangan basis data menggunakan Database Life Cycle yang memiliki lima tahapan: Requirements analysis, Logical design, Physical design, Implementation, Monitoring, modification, and maintenance. Tujuannya agar tahap pendefinisian basis data hingga tahap administasi dengan SQL Server 2019 konsisten dan efisien sehingga dapat dengan mudah diakses oleh berbagai platform seperti: Web, Desktop, Rest API dan lainnya.
PERANCANGAN SISTEM INFORMASI INVENTORY STOK BARANG PADA TB.RIFKY RAWAGENI BERBASIS JAVA
Authors: Wijiningsih Atik , Himawan Imam , Cleopatra Maria
Published: January 2023

Melihat perkembangan dan kemajuan teknologi informasi dan komunikasi, para pesaing bisnis dalam dunia industri semakin ketat. Jumlah perusahaan semakin banyak dan terus-menerus melakukan usaha dengan berbagai macam strategi dalam mempertahankan bisnisnya. Kesuksesan perusahaan dalam mempertahankan bisnisnya tidak akan terlepas dari peran perusahaan tersebut dalam mengelola inventory (persediaan) stok barang sehingga dapat memenuhi permintaan dari pelanggan semaksimal mungkin. Tujuan dari penelitian ini adalah untuk memperbaiki sistem informasi inventory stok barang pada TB.RIFKY Rawageni, yang masih menggunakan sistem manual menjadi sistem yang terkomputerisasi. Selain itu, hasil dari penelitian tugas akhir ini, penulis berharap penelitian ini dapat menjadi acuan sebagai referensi. Metode penelitian yang digunakan dalam penelitian ini adalah observasi, dimana penulis melakukan pengamatan secara langsung ke lokasi penelitian. Metode selajutnya yaitu wawancara, dimana penelitian melakukan wawancara kepada pemilik dan karyawan tempat penulis melakukan penelitian. Dalam penelitian ini penulis akhirnya dapat menarik kesimpulan bahwa aplikasi inventory stok barang ini dapat membantu memperbaiki sistem menjadi lebih efektif dan efisien dalam pengolahan data dan proses pembuatan laporan.
Pengaruh Penggunaan Media Pembelajaran Animasi Terhadap Hasil Belajar Matematika Siswa Kelas IV di Sekolah Dasar
Authors: Kamalia Addina , Rahmadhar Yulia
Published: January 2023

Tujuan penelitian ini yakni untuk melihat terdapat pengaruh atau tidaknya penggunaan media pembelajaran animasi terhadap hasil belajar Matematika siswa kelas IV Sekolah Dasar. Metode penelitian ini menggunakan penelitian kuantitatif berbentuk eksperimen quasi dimana metode ini digunakan untuk melihat adanya pengaruh atas suatu perlakuan terhadap varibel terikat. Desain yang digunakan ialah One Group Pretest-Posttest Design, yang berarti hanya satu grup yang nantinya akan menerima dua perlakuan sekaligus. Sampel penelitiannya yakni siswa kelas IV.a yang sebanyak 21 siswa/i berisi 12 siswa serta 9 siswi. Penelitian ini menggunakan teknik sampling jenuh yakni sampel penelitian yang akan digunakan adalah semua anggota populasi. Alat penelitian yang digunakan yakni format tes dengan menggunakan materi Bangun Datar, meliputi pretest dan posttest sebanyak 12 soal. Hasil yang di dapat pada penelitian ini memperoleh Thitung= 6,192 dan Ttabel = 1,725 pada ἀ= 0,05. Berdasarkan standar kriteria Thitung > Ttabel menunjukkan bahwa Hₒ ditolak dan H₁ diterima. Oleh karena itu, penggunaan media pembelajaran animasi berpengaruh terhadap hasil belajar Matematika siswa kelas IV di Dasar.
Pengaruh Model Pembelajaran ICARE Berbantuan Permasalahan Matematika Realistik terhadap Kemampuan Pemecahan Masalah Siswa Ditinjau dari Ketermapilan Berpikir Kritis
Authors: Hingnasari L. Virginayoga
Published: January 2023

Pasar modal memiliki peran yang cukup kuat dalam meningkatkan stabilitas ekonomi di suatu negara, Penelitian ini bertujuan untuk mengetahui pengaruh model pembelajaran ICARE berbantuan permasalahan matematika realistik terhadap kemampuan pemecahan masalah matematika siswa ditinjau dari keterampilan berpikir kritis siswa. Penelitian ini merupakan penelitian eksperimen semu dengan rancangan penelitiannya menggunakan desain faktorial 2´2. Penelitian dilaksanakan pada siswa kelas VII di SMP Negeri 9 Denpasar dengan sampel penelitian ditentukan menggunakan teknik cluster random sampling. Instrumen penelitian yang digunakan berupa tes keterampilan berpikir kritis dan tes kemampuan pemecahan masalah matematika. Data yang telah diperoleh dianalisis menggunakan analisis varians (ANAVA) dua jalur. Hasil yang diperoleh menunjukkan bahwa: 1) Kemampuan pemecahan masalah siswa yang dibelajarkan dengan model pembelajaran ICARE berbantuan permasalahan realistik lebih baik daripada kemampuan pemecahan masalah siswa yang dibelajarkan dengan model pembelajaran konvensional. 2) Terdapat interaksi antara model pembelajaran dengan keterampilan berpikir kritis terhadap kemampuan pemecahan masalah matematika siswa. 3) Pada siswa dengan tingkat keterampilan berpikir kritis tinggi, kemampuan pemecahan masalah siswa yang dibelajarkan dengan model pembelajaran ICARE berbantuan permasalahan realistik lebih baik daripada kemampuan pemecahan masalah siswa yang dibelajarkan dengan model pembelajaran konvensional. 4) Pada siswa dengan tingkat keterampilan berpikir kritis rendah, kemampuan pemecahan masalah siswa yang dibelajarkan dengan model pembelajaran konvensional lebih baik daripada kemampuan pemecahan masalah siswa yang dibelajarkan dengan model pembelajaran ICARE berbantuan permasalahan matematika realistik.
Metode Menghafal Al-Qur’an di Yayasan Tahfidz Qur’an Al-Husna Sei Kepayang
Authors: Arlina Arlina , Bagus Muhammad Syah , Mazid Miftah Ilham , Limbong Asmadi , Elsil Elda Arzetin
Published: January 2023

This study aims to analyze the method of memorizing the Qur’an YTQ al-husna Sei kepayang to foster Islamic religious education in the village. The focus of the Qur’an memorization method is the form of effort, supporting factors, and obstacles. This study analyzed the efforts made by UINSU students in Sei kepayang, Sei Kepayang district, east of Asahan Regency, North Sumatra. The research method used is qualitative based on descriptive studies. The data collection techniques used are observation, interviews, and documentation studies. The data that was proleh was then analyzed using Miles and Huberman's techniques, namely data reduction, data display, and drawing conclusions. The results of the study explained that the form of efforts made was to include children in non-formal religious education, foster children's religious practice at YTQ al-husna and be useful at home, and participate in diversity traditions based on local wisdom, getting children to grow up in surau. The supporting factors for the implementation of these efforts are the high motivation and expectations of parents for their children's education, besides being supported by a religious village environment. The inhibiting factor is that the busyness of parents at work is an obstacle to not being able to fully control the child's religious development.
Pengembangan Media Pembelajaran QuizWhizzer dan Kinemaster untuk Meningkatkan Motivasi Belajar Siswa di Sekolah Dasar
Authors: Iskandar Sofyan , Rosmana Primanita Sholihah , Fazriyah Aflahatul , Febriyano Agung , Rosyada Alya Amrina
Published: January 2023

This study aims to develop digital learning media using the video editor application kinemaster and Quizwhizzer as an evaluation to increase students' learning motivation in learning IPAS. Research The development of this learning media uses qualitative research methods. The research was conducted by observation to determine the success of student learning, researchers conducted pretest and posttest to students. From the observation results, it can be seen that learning using the video editor application kinemaster and quizwhizzer can increase student learning motivation, this can be seen when learning takes place, many students are active.
Nilai Pendidikan Tuturan Ritual Ka Nggua pada Masyarakat Paumere Desa Kerirea Kecamatan Nangapanda Kabupaten Ende
Authors: Pande Rikardus , Ola Simon Sabon , Semiun Agustinus
Published: January 2023

This study raises the educational value of the utterances of the Ka Nggua ritual carried out in the life of the Paumere people. This study aims to describe the educational value of the Ka Nggua ritual utterances carried out in the life of the Paumere people which are beneficial for the education of values, character and for the preservation of culture for the local community. The results of this study explain that the educational values contained in the ritual utterances of Ka Nggua, namely (1) the value of religious education as the main value in the life of the Pau mere people, (2) the value of moral education which teaches honesty, sincerity and openness, (3) ethical values teach self-awareness, sensitivity, adaptability, responsibility (4) cultural values that teach respect, inherit and preserve cultural customs, and (5) social education values that teach the nobility of cooperation, mutual cooperation, mutual assistance, mutual respect, cooperation, maintaining unity and brotherhood.
Bibliometric Analysis on Antenatal Depression: A Comparison of Research between Web of Science and China National Knowledge Infrastructure
Authors: Zhu Yuan , Wang Qiuqin , Ma Jiayuan , Wang Huimei , Xu Guihua
Published: January 2023

Background: Antenatal depression (AD) has adverse effects on mothers and children. While pregnant women in China are given less attention in terms of their mental health, in contrast, AD has resulted in increased interest at the international level. Methods: This study reviewed 1881 studies on AD from the Web of Science (WOS) and China National Knowledge Infrastructure (CNKI), using the bibliometric method in CiteSpace, to systematically analyze the research status, research hotspot, and potential trends of research on AD in China and abroad. Results: The results showed that: (1) There are 511 papers from the United States, followed by 210 from England, 136 from Australia, and 116 from Canada. Furthermore, articles from these four countries have the highest influence. And that the quantity and influence of papers published in China are relatively low; (2) Institution with the most publications is located in England, and those with the most influence are located in Australia and the United States; there are few Chinese institutions that publish on AD; (3) Literature on WOS clustered 7 hot topics, while documents on CNKI clustered 6, with similarities and differences; (4) With the passage of time, the researches of AD on CNKI gradually focused on the investigation and intervention of specific groups, while researches on WOS tend to consistently explore the biological and psychological mechanism and variety of intervention measures. Conclusions: It is the goal of China’s research to further explore the mechanisms and influencing factors of AD in order to better implement diversified interventions and improve the quality of life for mothers with AD and their offspring.
Challenges of Turner Syndrome Care in Adulthood: A Single Tertiary Center Experience
Authors: Robeva Ralitsa , Elenkova Atanaska , Zacharieva Sabina
Published: January 2023

Background: Turner syndrome (TS) is a well-known genetic condition associated with increased morbidity and mortality in adult patients. Accordingly, comprehensive guidelines for TS follow-up across the lifespan have been developed. However, the data about their implementation in clinical practice need to be expanded. The present study aims to describe a cohort of adult East-European TS patients and to highlight pitfalls in long-term medical care. Methods: Data from 45 TS women (18–53 years) were included in the present retrospective study. Personal history of the patients along with anthropometric, cytogenetic, clinical, and laboratory parameters were collected. Results: The median age of initial diagnosis was 15 years varying between one and forty-nine years, with nearly one-third of patients being diagnosed as adults. TS women treated with growth hormone during childhood were, on average, 5 cm taller than the non-treated patients (150.00 [147.00–155.00] vs. 145.00 [140.25–150.75], p = 0.055). Patients on hormone replacement therapy (HRT) had higher high density lipoprotein (HDL) cholesterol levels (1.80 mmol/L [1.44–1.99] vs. 1.55 mmol/L [1.31–1.74], p = 0.041) and lower follicle-stimulating hormone levels (33.70 IU/L [23.65 – 65.07] vs. 70.00 IU/L [46.90–79.39], p = 0.008) compared to non-treated women. Adherence to HRT was suboptimal, with only 55.6% of hypogonadal women being on hormonal treatment. The presence of comorbidities was increased as expected, but the percentage of hypertensive TS patients was lower than usually reported (11.1%). Conclusions: Growth hormone and estrogen replacement therapy might exert different positive effects on TS patients. However, the late diagnosis of TS and low adherence to treatment could limit the beneficial hormonal effects. A tendency for a more accurate diagnosis of concomitant endocrine diseases compared to non-endocrine conditions in TS patients has been observed. These results support the need for dedicated multidisciplinary teams focused on TS diagnosis and adult follow-up worldwide.
The Possibility of Deploying CO2 from Biogas Combustion to Improve the Productivity of a Periodical Chlorella vulgaris Culture
Authors: Zieliński Marcin , Kazimierowicz Joanna , Dębowski Marcin
Published: January 2023

Background: Carbon dioxide (CO2) is the major contributor to the global emissions of greenhouse gases, which necessitates the search for its fixation and utilization methods. Engaging photosynthesizing microorganisms for its biosequestration is one of the prospective technologies applied to this end. Considering the paucity of literature works on the possibilities of deploying CO2 from biogas combustion to intensify microalgae production, this research aimed to identify the feasibility of using this type of CO2 in Chlorella vulgaris culture by evaluating biomass production yield and CO2 biosequestration effectiveness. Methods: The experiment was performed in glass PBR, in which the culture medium occupied the volume of 1.0 dm3, and the gaseous phase occupied 0.3 dm3. The reactors were continuously illuminated by fluorescent lamps. The temperature of flue gases and air fed to reactors, and culture temperature was 20 °C ± 2 °C. Results: The use of flue gases promoted a more rapid biomass growth, reaching 77.8 ± 3.1 mgVS/dm3⋅d, and produced a higher microalgae concentration, i.e., 780 ± 58 mgVS/dm3. Nevertheless, the flue gas-fed culture turned out to be highly sensitive, which was manifested in a decreased culture medium pH and relatively quickly achieved decay phase of the C. vulgaris population. The microalgae effectively assimilated CO2, reducing its concentration from 13 ± 1% to 1 ± 0.5% in the effluent from the photobioreactor. Conclusions: The flue gases were found not to affect the qualitative composition of the microalgal biomass. However, strict control and monitoring of microalgae biomass production is necessary, as well as rapid responses in flue gas-fed systems. This is an important hint for potential operators of such technological systems on the large scale. Regardless of the possibility of deploying microalgae to fix and utilize CO2, a justified avenue of research is to look for cheap sources of CO2-rich gases.
Cellular Uptake, Metabolism and Sensing of Long-Chain Fatty Acids
Authors: He Qiburi , Chen Yuhao , Wang Zhigang , He Hu , Yu Peng
Published: January 2023

Fatty acids (FAs) are critical nutrients that regulate an organism’s health and development in mammal. Long-chain fatty acids (LCFAs) can be divided into saturated and unsaturated fatty acids, depending on whether the carbon chain contains at least 1 double bond. The fatty acids that are required for humans and animals are obtained primarily from dietary sources, and LCFAs are absorbed from outside of cells in mammals. LCFAs enter cells through several mechanisms, including passive diffusion and protein-mediated translocation across the plasma membrane, the latter in which FA translocase (FAT/CD36), plasma membrane FA-binding protein (FABPpm), FA transport protein (FATP), and caveolin-1 are believed to have important functions. The LCFAs that are taken up by cells bind to FA-binding proteins (FABPs) and are transported to the specific organelles, where they are activated into acyl-CoA to target specific metabolic pathways. LCFA-CoAs can be esterified to phospholipids, triacylglycerol, cholesteryl ester, and other specialized lipids. Non-esterified free fatty acids are preferentially stored as triacylglycerol molecules. The main pathway by which fatty acids are catabolized is β-oxidation, which occurs in mitochondria and peroxisomes. stearoyl-CoA desaturase (SCD)-dependent and Fatty acid desaturases (FADS)-dependent fatty acid desaturation pathways coexist in cells and provide metabolic plasticity. The process of fatty acid elongation occurs by cycling through condensation, reduction, dehydration, and reduction. Extracellular LCFA can be mediated by membrane protein G protein-coupled receptor 40 (GPR40) or G protein-coupled receptor 120 (GPR120) to activate mammalian target of rapamycin complex 1 (mTORC1) signaling, and intracellular LCFA’s sensor remains to be determined. The crystal structures of a phosphatidic acid phosphatase and a membrane-bound fatty acid elongase-condensing enzyme and other LCFA-related proteins provide important insights into the mechanism of utilization, increasing our understanding of the cellular uptake, metabolism and sensing of LCFAs.
Pharmaceutical Development of Intraperitoneal Arachis hypogaea as a Renal Protective Agent
Authors: Gul Arab , Khan Haroon , Shah Sayyed Ibrahim , Alsharif Khalaf F , Qahl Safa H , Rehman Inayat Ur , Goh Khang Wen , Ardianto Chrismawan , Ming Long Chiau
Published: January 2023

Background: Kidneys are among the vital organs of the human body; therefore, damage from any exogenous/endogenous agent may put human life at risk. Arachis hypogaea (AH) contains different free radical scavenging flavonoids, stilbenes, and tannins. This research aimed to elucidate the possible nephroprotective mechanism of AH methanolic crude extract (AHcr) and n-hexane oil fraction (AHO) against gentamycin-induced nephrotoxicity. Methods: After the extraction of the crude oil of the plant, they were tested against a Gentamycin (GM)-treated group of Swiss Albino mice for their nephroprotective action. Animals were divided into six (6) equal groups with five (5) animals in each group. These groups were: control group (0.5 mL normal saline via intraperitoneal -i.p), gentamycin group (gentamycin 100 mg/kg i.p), Silymarin + gentamycin group (Silymarin 50 mg/kg and gentamycin 100 mg/kg i.p), plant extract (AHcr1) and gentamycin group (AHcr1 250 mg/kg and gentamycin 100 mg/kg i.p), AHcr2 + gentamycin group (AHcr2; 500 mg/kg and gentamycin 100 mg/kg i.p) and the hexane oil fraction (AHO) + gentamycin (AHO 1 mL/kg and GM 100 mg/kg i.p). After completion of doses, animals were sacrificed for the collection of blood to further investigate biochemical changes and histopathological changes in kidney tissues. Results: Serum creatinine, urea, and blood urea nitrogen significantly increased (p < 0.001) in the gentamycin-treated group as compared to the control group. The elevated level of serum creatinine, urea, and blood urea nitrogen was decreased significantly (p < 0.001) in groups treated with AHcr and AHO compared to the gentamycin group. Similarly, the histopathological study of kidney tissues from the gentamycin group showed tubular necrosis, vacuolation, and fibrosis. Conclusions: The effect of crude extract and hexane soluble fraction of AH caused a significant reversal of gentamycin-induced nephrotoxicity.
Effect of L-Carnosine in Patients with Age-Related Diseases: A Systematic Review and Meta-Analysis
Authors: Sureshkumar Kaoshik , Durairaj Mahesh , Srinivasan Kaviya , Goh Khang Wen , Undela Krishna , Mahalingam Vijayakumar Thangavel , Ardianto Chrismawan , Ming Long Chiau , Ganesan Rajanandh Muhasaparur
Published: January 2023

Introduction: L-carnosine has been found to have multimodal activity. Aim: The aim of this review was to find out the efficacy of L-carnosine in patients with age-related diseases. Methods: Clinical studies evaluated the effect of L-carnosine on cancer, cardiovascular disease, diabetes, and neurodegenerative disorders were searched in electronic bibliographic databases. The protocol has been registered with PROSPERO (CRD42022314033). The revised Cochrane risk of bias tool for randomized trials was used to assess all of the reports for risk of bias. RevMan 5.4 was used to conduct the meta-analysis. Results: Following the screening process, 14 papers were selected for systematic review, with 9 of them being qualified for meta-analysis. Many of the included studies showed that L-carnosine has potential therapeutic activity in age related diseases. Results from the meta-analysis showed that in diabetes mellitus, HbA1c [mean difference (MD) 95% CI = –1.25 (–2.49, –0.022); p = 0.05; p = 0.001; I2 = 85%] and fasting blood sugar (FBS) [MD 95% CI = –12.44 (–22.44, –2.44); p = 0.01; p = 0.40; I2 = 0%] and in neurodegenerative disorder, Wechsler Memory Scale Logical Memory 2 (WMS-LM2) [MD 95% CI = 1.34 (0.83, 1.85); p < 0.00001; p = 0.43; I2 = 0%], showed statistically significant difference, favoring the L-carnosine group over the control group. While in neurodegenerative disorder, Alzheimer ’s Disease Assessment Scale (ADAS) [MD 95% CI = 0.98 (–1.55, –0.42); p = 0.0007; p = 0.86; I2 = 0%] and Back Depression Inventory (BDI) [MD 95% CI = –1.12 (–1.87, –0.37); p = 0.003; p = 0.73; I2 = 0%] showed statistically significant difference, favoring the control group over L-carnosine group. Conclusions: Clinical studies were conducted to manage chemotherapy induced toxicities and there are no clinical studies available for its anti-cancer use, and the current evidence does not support its use in the treatment of cardiovascular disease.
Hybrid Nanoparticles of Manganese Oxide and Highly Reduced Graphene Oxide for Photodynamic Therapy
Authors: Khan Haseeb A. , Lee Yong-kyu , Shaik Mohammed Rafi , Siddiqi Nikhat J. , Siddiqui Mohamed R. , Alrashood Sara T. , Alharbi Amal S. , Ekhzaimy Aishah A.
Published: January 2023

Background: Graphene-based nanomaterials possess unique optical, physicochemical and biomedical properties which make them potential tools for imaging and therapy. Manganese oxide nanoparticles are attractive candidates for contrast agents in magnetic resonance imagint (MRI). We used manganese oxide (Mn3O4) and highly reduced graphene oxide (HRG) to synthesize hybrid nanoparticles (HRG-Mn3O4) and tested their efficacy for photodynamic therapy (PDT) in breast cancer cells. Methods: The newly synthesized nanoparticles were characterized by transmission electron microscopy (TEM), energy-dispersive X-ray (EDX) spectroscopy, UV-visible spectroscopy, Fourier-transform infrared (FT-IR) spectroscopy, thermogravimetry, and X-ray diffraction (XRD) analyses. We used standard protocols of cytotoxicity and PDT after exposing A549 cells to various concentrations of hybrid nanoparticles (HRG-Mn3O4). We also performed fluorescence microscopy for live/dead cellular analysis. A549 cells were incubated with nanoparticles for 24 h and stained with fluorescein diacetate (green emission for live cells) and propidium iodide (red emission for dead cells) to visualize live and dead cells, respectively. Results: The cell viability analysis showed that more than 98% of A549 cells survived even after the exposure of a high concentration (100 μg/mL) of nanomaterials. These results confirmed that the HRG-Mn3O4 nanoparticles are nontoxic and biocompatible at physiological conditions. When the cell viability analysis was performed after laser irradiation, we observed significant and concentration-dependent cytotoxicity of HRG-Mn3O4 as compared to Mn3O4 nanoparticles. Fluorescence microscopy showed that almost 100% cells were viable when treated with phosphate buffered saline or Mn3O4 while only few dead cells were detected after exposure of HRG-Mn3O4 nanoparticles. However, laser irradiation resulted in massive cellular damage by HRG-Mn3O4 nanoparticles which was directly related to the generation of reactive oxygen species (ROS). Conclusions: HRG-Mn3O4 hybrid nanoparticles are stable, biocompatible, nontoxic, and possess therapeutic potential for photodynamic therapy of cancer. Further studies are warranted to explore the MRI imaging ability of these nanomaterials using animal models of cancer.
Abscopal Effect Following Cryoablation in a Patient with Metastatic Breast Cancer
Authors: Kaplan Jamie L. , Turker Ismail , Chumsri Saranya , Gabriel Emmanuel
Published: January 2023

While breast cancer is a common disease with many available treatment options, many patients still have limited responses, especially those with metastatic breast cancer. Surgery of the primary tumor or metastatic sites is often not part of the treatment regimen for patients with metastatic breast cancer. Cryoablation is a relatively non-invasive procedure that is being investigated for patients with breast cancer. Patients with metastatic breast cancer who are not surgical candidates may derive benefit from cryoablation through the abscopal effect. In this case report, we present a patient with stage IV breast cancer who was treated with cryoablation of the primary breast tumor and showed evidence of an abscopal effect in regional and distant metastases.
Striatal Subregion Analysis Associated with REM Sleep Behavior Disorder in Parkinson's Disease
Authors: Kwak In-hee , Lee Yun Kyoung , Ma Hyeo-il , Lee Sangwon , Yun Mijin , Kim Yun Joong , Hwang Hee Sung , Kim Young Eun
Published: January 2023

Background and Purpose: REM sleep behavior disorder (RBD) in Parkinson’s disease (PD) is associated with characteristic clinical subtypes and prognosis. In addition, nigrostriatal pathway, the most vulnerable anatomical area in PD, formed neuronal network interplaying with cortical and subcortical structures, and which may cause PD clinical phenotype. We evaluated the regional selectivity of presynaptic striatal dopaminergic denervation associated with RBD in PD. Methods: We compared two groups (n = 16) of PD patients with and without RBD in terms of specific binding ratios (SBR) in subregions of the striatum, which were measured using positron emission tomography with 18F-FP-CIT. SBRs of the anterior and posterior caudate, ventral striatum, and posterior and ventral putamen regions were measured in more or less affected side, and right or left side, or bilateral sum of the striatum. Results: Age, disease duration, and severity of parkinsonism were not significantly different between groups. Although group differences in all areas were not significant with multiple comparison corrections, SBR of the ventral striatum and anterior caudate in sum of both sides was significantly less in the RBD than in the non-RBD group without correction (p < 0.05). In the right anterior caudate and left ventral striatum, SBR was also lower in the RBD than in the non-RBD group without correction (p < 0.05). Attention function was impaired in the RBD group compared with the non-RBD group (p < 0.05). However, these statistical significances were not definite after correction of multiple comparisons (p > 0.05). Conclusions: There is a possibility that RBD in early PD may be associated with presynaptic dopaminergic denervation in the ventral striatum and anterior caudate, which may explain decreased attention in our RBD group. RBD in PD may imply a distinct pathological progression. However, further study using large numbers of participants or longitudinal observation is necessary for the statistical conclusion because of small sample size.