bluuebunny/crossref_metadata_2025 huggingface dataset:
DEVELOPMENT OF THE DESIGN OF THE PRECLINICAL TRIALS OF RADIOPHARMACEUTICALS FOR THE RADIONUCLIDE DIOAGNOSTICS AND THERAPY BASED ON THE AMBA PEPTIDE
Authors: Stanzhevsky Andrey A. , Mosunov Artem A. , Chipiga Larisa , Vodovatov Aleksandr V. , Naurzbaeva Laura , Kushnarenko Stanislav M. , Lavreshov Dmitry D. , Petrova Anna E.
Published: December 2020

The use of the bombesin analogues labeled with 68Ga and 177Lu for the radionuclide diagnostics and therapy of the prostate cancer, respectively, is one of the novel and promising approaches of the nuclear medicine. These radiopharmaceuticals are currently on the stage of preclinical and clinical trials in the foreign countries; in the Russian Federation, a preclinical trial is being developed.

The aim of the current study was to develop the design of the preclinical study for the radiopharmaceuticals based on AMBA for the assessment of their biodistribution.

The study was based on the meta-analysis of the available publications in peer-reviewed journals. The analysis was performed using the full-text archive of biomedical and life sciences journals PubMed Central for the following keywords: radionuclide therapy, nuclear medicine, AMBA, 68Ga и 177Lu. The study included the comparative analysis of the animal and patient samples, methods of data collection and results of the accumulation of radiopharmaceuticals in nodules and radiosensitive organs and tissues.

The results of the study allowed proposing the minimal requirements for the animal samples (at least 30 animals for each radiopharmaceutical), data collection (direct radiometry and PET) and time points (not less than 5 measurements in 120-240 minutes for the radiopharmaceuticals labeled with 68Ga and 5 measurements in 336 hours for the radiopharmaceuticals labeled with 177Lu) for the assessment of the biodistribution of the radiopharmaceuticals.
A Ground-Motion Prediction Model for Shallow Crustal Earthquakes in Greece
Authors: Boore David M. , Stewart Jonathan P. , Skarlatoudis Andreas A. , Seyhan Emel , Margaris Basil , Theodoulidis Nikos , Scordilis Emmanuel , Kalogeras Ioannis , Klimis Nikolaos , Melis Nikolaos S.
Published: December 2020

Using a recently completed database of uniformly processed strong-motion data recorded in Greece, we derive a ground-motion prediction model (GMPM) for horizontal-component peak ground velocity, peak ground acceleration, and 5% damped pseudoacceleration response spectra, at 105 periods ranging from 0.01 to 10 s. The equations were developed by modifying a global GMPM, to account for more rapid attenuation and weaker magnitude scaling in the Greek ground motions than in the global GMPM. Our GMPM is calibrated using the Greek data for distances up to 300 km, magnitudes from 4.0 to 7.0, and time-averaged 30 m shear-wave velocities from 150 to 1200  m/s. The GMPM has important attributes for hazard applications including magnitude scaling that extends the range of applicability to M 8.0 and nonlinear site response. These features are possible because they are well constrained by data in the global GMPM from which our model is derived. An interesting feature of the Greek data, also observed previously in studies of mid-magnitude events (6.1–6.5) in Italy, is that they are substantially overpredicted by the global GMPM, which may be a repeatable regional feature, but may also be influenced by soil–structure interaction. This bias is an important source of epistemic uncertainty that should be considered in hazard analysis.
Unjuk Kerja Pengering Tenaga Surya Tipe Efek Rumah Kaca Untuk Pengeringan Cabai Dengan Perlakuan Low Temperature Long Time Blanching
Authors: Irfan Andi Muhammad , Arimansyah Arimansyah , Rasyid A. Ramli , Lestari Nunik
Published: December 2020

Abstrak. Penelitian ini bertujuan untuk menguji unjuk kerja pengering tenaga surya tipe efek rumah kaca pada pengeringan cabai dengan perlakuan low temperature long time (LTLT) blanching. Selain itu, pada penelitian ini juga dilakukan kajian mengenai karakteristik pengeringan cabai yang dipengaruhi oleh perlakuan LTLT blanching, terutama pada kadar air, laju pengeringan, kecepatan pengeringan, dan kualitas warna. Pengujian dilakukan dengan cara mengeringkan cabai merah dengan pretreatment LTLT blanching yang dikombinasikan dengan perlakuan merotasikan rak pengering (R) dan tanpa merotasikan rak pengering (TR). Sebagai kontrol adalah cabai yang dikeringkan tanpa blanching dan tanpa merotasikan rak pengering (K). Hasil penelitian menunjukkan bahwa perlakuan LTLT blanching yang dikombinasikan dengan merotasikan rak pengering (R) merupakan perlakuan yang terbaik, dengan kadar air akhir cabai kering sebesar 9,82% dan sesuai dengan standar SNI. Waktu pengeringan yang dibutuhkan adalah selama 5 hari. Warna cabai kering yang dihasilkan adalah yang terbaik dari dua perlakuan lainnya, dengan nilai L*, a*, dan b* untuk setelah proses LTLT blanching (sebelum proses pengeringan) dan setelah pengeringan berakhir (cabai kering) berturut-turut adalah 36,02, 38,22, 13,62, dan 32,44, 33,89, dan 10,19. Energi yang terpakai untuk pengeringan cabai adalah sebesar 596181 kJ. Perlakuan R ini juga menghasilkan efisiensi pengeringan terbaik, yaitu sebesar 34,01%.Performance of Green House Effect Type Solar Dryer in the Chillies Drying with Low Temperature Long Time Blanching TreatmentAbstract. This study aims to examine the performance of the greenhouse effect type solar dryer on drying chillies with low temperature long time (LTLT) blanching treatment. In addition, a study was also conducted on the characteristics of drying chillies and the final product affected by LTLT blanching treatment, especially in terms of moisture content, drying rate, drying speed, and color. Testing was performed by drying red chilli with LTLT blanching treatment, which was combined with the treatment of rotating dryer rack (R) and without rotating dryer rack (TR). As a control, chillies were dried without blanching treatment and without rotating dryer rack (K). The results show that the LTLT blanching treatment combined with rotating the drying rack (R) is the best treatment, with a final moisture content of 9.82% which is in accordance with SNI standards. The drying time needed is 5 days. The dried chilli color produced is the best of the other treatments, with values of L*, a*, and b* for after the LTLT blanching process and after drying ended, respectively 36.02, 38.22, 13.62, and 32.44, 33.89, 10.19. The energy used for drying chillies is 596181 kJ. This R treatment also produces the best drying efficiency, which is 34.01%.
Synthesis and Properties of Bisthiadiazoles with Ethyl and Butyl Spacers
Authors: Suvorova Yu. V. , Petukhova E. A. , Danilova E. A. , Tyurin D. V.
Published: December 2020

This article is devoted to a selection of the most effective preparative method for the synthesis of bis(5-amino-1,3,4-thiadiazole-2-yl)alkanes. These compounds are binuclear diamines consisting of symmetrical 1,3,4-thiadiazole fragments connected by alkyl spacers of various lengths. The structures of the obtained compounds were determined by IR spectroscopy, mass-spectrometry and elemental analysis. The possibility of using these molecules as precursors for the synthesis of macroheterocyclic compounds with expended coordination cavity consisting of six small cycles was demonstrated. Optimal synthesis conditions of bis(5-amino-1,3,4-thiadiazole-2-yl)ethane and bis(5-amino-1,3,4-thiadiazole-2-yl)butane were found by variation of reaction time and temperature. Virtual screening of the obtained compounds was carried out in order to predict antibacterial and biological activities as well as toxic properties of the targeted products. On the basis of the known literature data on polynuclear diamines, the exhibition of the liquid crystal properties of the synthesized molecules is supposed.
Targeted drug delivery system for doxorubicin based on a specific peptide and phospholipid nanoparticles
Authors: Kostryukova L.V. , Tereshkina Y.A. , Korotkevich E.I. , Prozorovsky V.N. , Torkhovskaya T.I. , Morozevich G.E. , Toropygin I.Y. , Konstantinov M.A. , Tikhonova E.G.
Published: December 2020

Doxorubicin is one of the widely known and frequently used chemotherapy drugs for the treatment of various types of cancer, the use of which is difficult due to its high cardiotoxicity. Targeted drug delivery systems are being developed to reduce side effects. One of the promising components as vector molecules (ligands) are NGR-containing peptides that are affinity for the CD13 receptor, which is expressed on the surface of many tumor cells and tumor blood vessels. Previously, a method was developed for preparing a composition of doxorubicin embedded in phospholipid nanoparticles with a targeted fragment in the form of an ultrafine emulsion. The resulting composition was characterized by a small particle size (less than 40 nm) and a high degree of incorporation of doxorubicin (about 93%) into transport nanoparticles. When assessing the penetrating ability and the degree of binding to the surface of fibrosarcoma cells (HT-1080), it was shown that when the composition with the targeted fragment was added to the cells, the level of doxorubicin was almost 2 times higher than that of the liposomal form of doxorubicin, i.e. the drug in the system with the targeted peptide penetrated the cell better. At the same time, on the control line of breast adenocarcinoma cells (MCF-7), which do not express the CD13 receptor on the surface, there was not significant difference in the level of doxorubicin in the cells. The data obtained allow us to draw preliminary conclusions about the prospects of targeted delivery of doxorubicin to tumor cells when using a peptide conjugate containing an NGR motif and the further need for its comprehensive study.
The Importance of Food Packaging Containers in Marketing
Authors:   The College of Business, Jiangsu University of Technology, China, Chen Pei-Yu , Chen Shun-Hsing , Chang Hsiao-Ming
Published: December 2020

As food safety is tied up with the strength of the country and also associated with the protection of the individual’s life, the materials used in packaging and the containers are of great importance. Not only has the plasticizer incident triggered a crisis in food additives, but it also induced the infiltration hazard of packaging containers. This study aims to explore the green business opportunities of food packaging containers and the impacts of different materials on packaging containers based on the circular economy. A comparative analysis was done between the environmentally friendly inks and traditional inks to emulate the advantages and disadvantages of plastic, paper, glass, and metal materials. Finally, R&D was carried out to discuss the overall results and benefits of creative edible tableware. The study found that we should follow and implement the experience of advanced countries and future trends. The consumers’ desire for environmentally friendly, creative, and diversified food packaging containers is one thing that needs urgent consideration.
Construction and Practice of Excellence Talent Training System for Computer Science and Technology in Yunnan University
Authors:   School of Information Science & Engineering, Yunnan University, Kunming, China, Yuan Guowu , Luo Gaifang , Yang Xutao , Yue Kun , Qian Wenhua
Published: December 2020

Taking the computer science and technology of Yunnan University as an example, the ideas and methods of training excellent talents are expounded in this paper. This major trains excellent talents from four points: classified training based on course group, collaborative education based on school-enterprise cooperation, computer professional certification and construction of practice innovation base. By setting up three course groups and dividing each course group into application type and research type, the individualized classified training of students can be realized. Through school-enterprise cooperation and education project, the industry enterprises deeply participate in the training process, and the students become industry-recognized talents. Through Certified Software Professional (CSP) organized by China Computer Federation (CCF), talents are trained according to industry standards. Through the construction of practice and innovation base, we will change to "learning by doing" which centers on students and focuses on students' active practice, and strengthen the cultivation of students' engineering ability and innovation ability. It can provide reference for the construction of computer talent training in relevant universities.
To Meet the Trend of AI: The Ecology of Developing AI Talents for Pre-service Teachers in China
Authors:   Educational Development Department, Hanshan Normal University, Chaozhou, PR China, Xia Li , Zheng Gengzhong
Published: December 2020

In answering the tremendous achievement and growing advancement in the age of Artificial Intelligence (hereafter AI) in China and across the world, China has issued a series of political statements on developing AI including its national guideline on the development of AI in 2017. In contrast to the grooming applications of AI technologies in the field of engineering, agriculture, medicine etc, the deficiency of qualified and certified AI teachers for all grades is one of the major barriers that China is now facing in promoting its national AI scheme. This paper analyses the current situation observed in the east part of Guangdong Province and proposes a model that integrates regional government, regional normal universities, elite universities, AI companies and local primary and secondary schools as a unified organisation with regional normal universities(normal universities are the universities specifically founded for nurturing teachers at primary and secondary school education) as the central coordinator facilitating the smooth cooperation between different parties. This model which addresses the development of AI talents for pre-service teachers has the potential to be applied to other less-developed regions in China.
Research and Practice on Compound Talents Training Model of Safety Management—A Case Study from Xi'an University of Science and Technology
Authors:   Department of Safety Engineering, School of Safety Science and Engineering, Xi'an University of Science and Technology, Xi'an, Shaanxi Province, China, Wang Li , Tian Shuicheng , Cheng Lianhua , Li Lei
Published: December 2020

The current frequent occurrence of major accidents shows the urgent need of the society for compound talents in safety management. At present, the training of safety engineering talents in colleges and universities is more prominent in the safety knowledge and skills of students in their professional fields. Therefore, by analyzing the problems existing in the training of safety engineering professionals in engineering colleges and universities, the necessity of cultivating safety management talents has been discussed. According to the questionnaire, we can understand the social needs of safety management talents and analyze the knowledge structure of safety management talents. It also introduces the attempts of Xi'an University of Science and Technology(XUST) in the training of safety management compound talents. Through exploring the training method of safety management compound talents, it provides a reference for improving students' comprehensive practical ability and innovative ability in safety technology and management.
ANALYTICAL AND COMPARATIVE INVESTIGATION OF PARTICULATE SIZE EFFECT ON SLURRY FLOW CHARACTERISTICS USING COMPUTATIONAL FLUID DYNAMICS
Authors: PARKASH Om , KUMAR Arvind , SİKARWAR Basant
Published: December 2020

The key issue associated with the industries is the transportation and dumping of solids particulates in the form of slurry at the desired place using long length pipelines. In this perspective, numerical simulation of three-dimensional horizontal slurry pipeline of 0.0549 m diameter using Eulerian two-phase model with RNG k-ɛ turbulence closure is carried out. The glass - beads solid particulates having density ( = 2470 kg/m3) and slurry concentration varies as 10% to 50% (by volume) for velocity ranges of 3-5 ms-1. The computational modeling is done using available commercial software ANSYS Fluent for 125µm and 440 µm particulate size at different velocity and concentration range to know their effect on slurry flow characteristics. It is observed that for chosen particulate size pressure drop increases with increase in velocity at all solid concentration range. The pressure drop in slurry for 440 µm solid particulates is found higher as compared to the pressure drop of 125 µm solid particulates slurry. The percentage change in pressure drop is also reported in the paper due to particulate size effect at all velocity and solid concentration. The obtained results of predicted pressure drop are analytically compared with the available experimental results of literature and are in synchronism with that. A parametric study is carried out with the aim of visualizing and understanding the solid particulate size effect on slurry flow characteristics. Finally, the results of settling solid concentration contour, velocity contour, concentration profiles, velocity profiles and vector representation of concentration/velocity were also predicted for chosen particulates sized slurry.
Prevalence and risk factors associated with depressive symptoms among end-stage renal disease patients undergoing hemodialysis in Indian setting
Authors: Bhatia Rajeev Kumar , Marwaha Ajay
Published: December 2020

Background: This study aimed to evaluate the prevalence of depressive symptoms among the patients with end-stage renal disease (ESRD) on hemodialysis and to explore associated risk factors.Methods: A prospective observational study of patients with ESRD undergoing hemodialysis were included in the study. Data was collected based on questionnaire created by the study team, and by verbal interviews with patients. The questionnaire consisted of two parts, which included demographic data (gender, age, sleep quality, duration of sleep, appetite pattern, and duration of dialysis) and evaluation of the severity of depressive symptoms by using the depression, anxiety and stress scale-21.Results: Out of total 93 patients with ESRD on hemodialysis majority of patients belonged to the age group of >60 to ≤80 years (47.8%) and age group >40 to ≤60 years (40.0%). Patients had a higher incidence of severe anxiety (38.7%) than depression (34.4%), and stress (22.6%). The proportion of patients diagnosed with depression (50.0%) and stress (57.1%) was higher in the older age group (>60 to ≤80 years); while the proportion of patients having severe anxiety was similar in both adult (>40 to ≤60 years) and older (>60 to ≤80 years) age group (38.9%). More than 50% of patients with depressive, anxiety, and stress symptoms had insufficient sleep (≤1 to ≤4 h). The present study could not predict the risk factors of depressive symptoms in patients with ESRD on hemodialysis.  Conclusions: Depression and anxiety symptoms were more frequent among patients with ESRD undergoing hemodialysis in Indian settings.
Outcome of pterygium surgery by using conjunctival autograft attachment with fibrin glue: a prospective study
Authors: Kaur Happy , Maqbool Babar , Kaur Manpreet
Published: December 2020

Background: Pterygium is a degenerative condition of sub conjunctival tissues that proliferates as vascularised granulation tissue to invade cornea. Treatment modalities may be medical or surgical. Objectives were to asses results of pterygium surgery in patients with pterygium, in terms of operative time, post-operative symptoms, overall graft success and post-operative complications conducted at government medical college, hospital, Jammu during one year.Methods: Prospective study conducted on 25 patients by using fibrin glue over a period of one year in upgraded department of ophthalmology at GMC Jammu.Results: Mean operating time was 23.20 minutes by using fibrin glue, severity of post-operative symptoms were less. Graft successfully attached in all cases.Conclusions: Present study concluded that use of fibrin glue associated with less operating time and less post-operative discomfort in terms of severity and duration
A comparative study of efficacy between transforaminal epidural injection and selective nerve root block in disc prolapse of L4-L5 and L5-S1
Authors: Ghosh Arindam , Ghorai Debayan , Dutta Dibyendu
Published: December 2020

Background: To compare efficacy between transforaminal epidural injection (TFEI) and selective nerve root block (SNRB) in prolapsed L4-L5 and L5-S1 disc.Methods: This study was a randomized parallel group open label interventional study. Patients suffering from low back pain (LBP) with radiation due to prolapsed inter-vertebral disc (PIVD) were selected for intervention (n=78). After computer generated randomization, they were allocated into two groups (TFEI group and SNRB group) consisting 39 patients in each group. Each patient received combination of 2 ml of depot methylprednisolone acetate (40 mg/ml) and 1 ml of 0.25% preservative free bupivacaine under fluoroscopy guidance.                                                                                                            Primary outcome measures were visual analogue scale (VAS) score of LBP and VAS score of radiation pain. Secondary outcome measure was Oswestry LBP disability questionnaire (ODQ) score.Results: At 1-day post-intervention TFEI group showed statistically significant improvement in VAS score of LBP (p=0.000) as compared to SNRB group. At 1-month post-intervention TFEI group showed statistically significant improvement in VAS score of LBP (p=0.000) and VAS score of radiation pain (p=0.000) as compared to SNRB group. At 3-month post-intervention TFEI group again showed statistically significant improvement in VAS score of LBP (p=0.000), VAS score of radiation pain (p=0.000), and ODQ score (p=0.000) as compared to SNRB group.Conclusions: TFEI is better than SNRB in terms of improvement in LBP, radiation pain, and functional activity up to 3-month post-intervention.
Burden of drug induced allergic reactions: a 3-year experience in a tertiary care hospital
Authors: Mukherjee Shatavisa , Tripathi Santanu Kumar
Published: December 2020

Background: DIARs includes a wide spectrum of immunologically-mediated hypersensitivity reactions with varied mechanisms and clinical manifestations. Besides affecting a patient’s quality of life, it may also lead to increased treatment cost and length of hospitalization. The present study aims to provide an overview of drug induced allergic reactions experienced in a tertiary care set-up.Methods: A prospective observational outcome research was conducted over a 3-year period on patients encountering drug induced allergic reactions, who has been analysed for their spectrum of presentation, clinical outcomes (including severity, management and outcome of reaction), economic outcomes (including cost of treatment) and humanistic outcomes (including assessment of quality of life).Results: Drug induced allergic reactions accounts for 2.71% of total hospitalization in this study period. While majority reactions were moderate in severity grading, most were preventable. Direct cost of treating such preventable reactions were much higher along with increased indirect cost (due to prolonged hospitalization) adding to economic burden. Quality of life in patients encountering such reactions was also compromised as assessed using EQ-VAS.Conclusions: Prompt identification, consultation, cessation of culprit drug, management and patient counselling can act as strategies to minimize the burden of these reactions on society and healthcare system at large.
Rare presentation of hallucinations in cerebellar multisystem atrophy
Authors: D'Souza Galina L. , K. Priya Nayak
Published: December 2020

Psychotic symptoms are seen in patients with medical disorders. Multisystem atrophy (MSA) is a neurodegenerative disorder which is rapidly progressive. It can occur in two forms; one with parkinsonian features (MSA-P) and other with cerebellar ataxia (MSA-C). The prevalence of this disorder is about 2-5 per 1,00,000 individuals. Neuropsychiatric symptoms like depression, apathy and anxiety have been reported frequently in these patients but there are isolated reports describing hallucinations in patients with MSA. It is mostly seen in patients with parkinsonian type of MSA rather than cerebellar type of MSA. Here we report a rare case of psychotic disorder in a patient with cerebellar type of multi-system atrophy.
Critical factors leading to wound complications in amputated patients: low hematocrit levels
Authors: Omeroglu Sinan , Demir Ibrahim , Beyaz Metin O.
Published: December 2020

Background: Patients with diabetes-induced lower extremity infection and gangrene suffer from post-amputation wound complications. The aim of this report is to identify critical factors leading to wound complications in amputated patients.Methods: 50 patients with ipsilateral transmetatarsal (TMA) or finger amputation treated in Istanbul University Medical Faculty between 2001 and 2013 were retrospectively reviewed. Amputations were caused by diabetic foot infection. None of the patients had peripheral artery disease (ABPI>1.1).Results: In 9 (18%) patients, revision was required despite appropriate antibiotherapy after amputation. 7 (78%) of these patients were women, 8 (89%) were smokers and hematocrit levels were below 25% in all of them. 4 of the 5 patients (80%) with chronic kidney disease were among the patients in need of revision.Conclusion: The risk of wound complications after amputation is high. These complications increase morbidity and treatment costs. This study showed that low hematocrit value is a risk factor for the development of wound infection after amputation.
A comparative study on topical recombinant human epidermal growth factor vs conventional betadine dressing in management of diabetic wounds
Authors: Kundal Ajay , Kohli Manu , Kapoor Sudershan
Published: December 2020

Background: Major complications of diabetes mellitus include cardio vascular disease, chronic kidney disease, diabetic foot ulcers and non-healing wounds. Lack of knowledge and awareness has led to worsening of wounds which can involve deeper tissues and bones also. If treated on time majority of patients can be prevented from undergoing major debilitating surgical procedures such as amputation of toes, foot etc.Methods: In this proposed study, 60 cases of diabetic wounds were studied for healing who were randomly allocated into two groups of 30 patients each. Group A included topical recombinant epidermal growth factor (EGF) application and group B included conventional Betadine dressing for wound healing.Results: Anaemia had a significant role in delaying wound healing in group B patients. Blood sugars had no significant role in delaying wound healing in this study as patients in group A had mean FBS more than group B and still the wound healing was observed better in group A patients. Topical recombinant EGF resulted in faster wound healing than conventional dressings in diabetic wounds. 90% wound healing rates were seen with topical EGF dressings in comparison to 36.67% in conventional betadine dressings. Signs of wound healing i.e., early granulation, decreased discharge, early wound closure were seen faster in group A. Moreover, all patients in group A showed healthy granulation tissue by the end of our study.Conclusions: We concluded that topical recombinant EGF resulted in faster and better wound healing than conventional betadine dressing.
Clinical profile of patients with intussusception in a tertiary care institution in South India
Authors: San Diljith , P. Ranjit , Ainippully Arun M.
Published: December 2020

Background: Intussusception is a common abdominal emergency in children. It is the most common cause of intestinal obstruction in children less than 2 years. Awareness about the clinical presentation vomiting, abdominal pain, blood in stools, abdominal mass helps in early diagnosis. This study describes the demographics and clinical profile of patients with intussusception in a tertiary care institute in South India.Methods: This was a prospective case series study conducted in the pediatric surgery department in a tertiary care hospital in South India. Children upto 12 years with clinically and radiologically confirmed intussusception were enrolled over 12 months study period. Demographic and clinical data was collected and recorded.Results: Eighty two children with clinical and radiological picture suggestive of intussusception were studied. 57 patients (75%) were below 1 year of age. Male:female ratio was 1.7:1. The classical triad of abdominal colic, palpable abdominal mass and rectal bleeding was seen in 39 patients (50%). Most common signs were rectal bleed and abdominal mass.Conclusions: Awareness about the clinical presentation of intussusception helps in early diagnosis and prompt treatment of this common pediatric emergency and helps to prevent mortality.
Study on hydrostatic reduction of intussusception under general anaesthesia without ultrasound guidance
Authors: San Diljith , P. Ranjit , Ainipully Arun M.
Published: December 2020

Background: Currently the recommended treatment for intussusception is ultrasound guided hydrostatic reduction under sedation. The procedure is very safe due to real-time visualisation, but inadequate sedation and absence of muscle relaxation may cause difficulty during the procedure. Muscle relaxation under general anaesthesia will make reduction of mass easier. In this context, we conducted this study of hydrostatic reduction of intussusception under general anaesthesia without USG guidance.Methods: In this prospective study eighty two children were treated for intussusception from January 2010 to December 2010. General anaesthesia was induced and lump was confirmed. Normal saline was infused through Foleys catheter and i.v. drip set into rectum from saline bottle kept 3 feet above operating table. Saline reduction was done, and if not reduced a second attempt was done. Partially reduced or failed cases underwent immediate surgery. In successful cases, reduction was confirmed by ultrasound.Results: Hydrostatic reduction under general anaesthesia was done in 78 children. In 54 patients (68%) procedure was successful with no residual mass in check ultrasonogram. 24 (30.7%) patients required surgical treatment, immediate surgery in 18 and delayed surgery in 6 patients. Procedure was uncomplicated in 77 patients (98.7%). One patient developed peritonitis due to delayed presentation.Conclusions: Hydrostatic reduction is treatment of choice in intussusception unless contraindicated. Hydrostatic reduction under general anaesthesia without ultrasound guidance is safe and effective. Hospital stay is less for hydrostatic reduction. Failure with hydrostatic reduction is more if mass extends distal to splenic flexure. Most failed cases were easily reducible by laparotomy.
Comparison of STONE score with Guy’s stone score as a tool to predict stone clearance rates in patients undergoing percutaneous nephrolithotomy: a single center study
Authors: Handa Anoop , Dash Sharat Chandra , Solanki Nimit , Shukla Abhishek , Singh Gagandeep , Jha Aditya Abhishek , Khandelwal Sachin
Published: December 2020

Background: We aimed to compare the Guy’s stone score and STONE nephrolithometry score and assess their predictive accuracy for percutaneous nephrolithotomy (PCNL) outcomes.  Methods: A total of 100 patients, who underwent PCNL between Jan 2018 and Dec 2018 were included in the study. All patients were evaluated with computerized tomography (CT) scan preoperatively and scores were calculated. Patient demographic characteristics, intraoperative and postoperative variable were evaluated. The relationship between the Guy’s and STONE scores, and their prediction for postoperative stone-free status, complications were compared. Results: The mean Guy’s score was 2.04±1.01, and the mean STONE score was 8.0+1.7. The mean operative time was 101.9+41 minutes and the mean blood loss was 170+113ml. The complication rate in our study was found to be 32%, majority were grade 1-2. Both scoring systems showed positive correlation with stone burden, operating time and blood loss. The overall stone free rate was 72% and both the GSS and STONE score were significantly associated with success of the procedure.  Conclusions: Both Guy’s and STONE scoring systems are equally effective in predicting stone-free status.
Trichobezoar: a rare clinical rendezvous with twin sisters
Authors: Almuawi Abdulrahman , Alsamahy Omar , Fahiem-Ul-Hassan Mir , Abdelhamid Brahemi
Published: December 2020

Trichobezoar is very uncommon in the pediatric age group. Till now no familial predisposition has been reported. We hereby report our clinical experience with eight years old twin sisters one of whom had a huge gastric trichobezoar and other one had a history of trichotillomania with recurrent vomiting and weight loss. An eight years old female child, one of the twin, presented with history of recurrent vomiting. Abdominal examination revealed firm mass in epigastric region. X-ray abdomen showed the transverse colon pushed down. Ultrasonography revealed echogenic mass in the stomach. Preoperative diagnosis of trichobezoar was achieved by a computed tomography (CT) scan. Laparotomy was done through the midline abdominal incision after initial session of resuscitation. A huge mass of hair was retrieved from the stomach part of which was passing into the duodenum. Patient was found to have underlying trichotillomania and obsessive compulsive disorder. As the patient was one of the twins, other sibling was called and evaluated for the mental health. Interestingly, she was found to have trichotillomania and trichophagia. Examination revealed sparse scalp hair. X-ray and the sonography of the abdomen were normal. Patient was advised endoscopic examination which the guardian of the patient refused. Patient was put on outpatient department (OPD) follow up after psychiatric counselling. Trichobezoar should be suspected in a pediatric patient of gastrointestinal symptoms, epigastric mass and anemia with history of trichophagia. Open surgery gives optimum results. Sibling of an affected twin must be evaluated on the similar lines and managed accordingly.
Cystic lymphangioma of breast and axillary region in an adult: a rare presentation
Authors: Shukla Samir , Shivhare Rahul , Lal Vikas , Rathore Deepak
Published: December 2020

Cystic lymphangioma also known as cystic hygroma, is a congenital malformation of lymphatic system. Most lymphangioma are present at birth and are diagnosed by the age of 2 years. They are usually located in the head and neck region and are rare in other location. We are reporting a case of cystic lymphangioma in breast and axillary region in a 23 years old female. Physical examination revealed a non-tender cystic mass in axilla and upper outer quadrant of left breast. Ultrasonography (USG) revealed a hypoechoic mass lesion and magnetic resonance imaging (MRI) showed a multi-spectated cystic mass in left axilla closely involving the left breast parenchyma. Wide local excision was done and histopathological examination further confirmed the diagnosis of cystic lymphangioma. Although it is very rare, cystic lymphangioma should be considered in the differential diagnosis of mass in breast and axillary region.
Safety Monitoring and Evaluation of Construction Projects Based on Multi-sensor Fusion
Authors: Ni Na
Published: December 2020

For most construction projects, the complex engineering environment, the backward data collection technology, and the unreasonable monitoring network have resulted in many problems in monitoring data such as lots of noise and missing data items, therefore, it is of great significance to study the safety monitoring system of construction projects based on wireless sensor network (WSN). For this reason, this paper proposed a construction safety monitoring and evaluation (CSME) model based on multi-sensor fusion. First, the system structure and data flow model of the construction safety monitoring system were constructed; then, combining with a multi-sensor deep fusion system which was built on physical and information systems, this paper designed a spectrum sensing algorithm for sensor signals within the construction area. After that, tempo-spatial correlation analysis was conducted on the monitoring data, and a multi-sensor monitoring network joint sparse (MSMN-JS) model was constructed, which realized reconstruction of missing data items. At last, this paper used experimental results to prove the application value of the algorithm model to the safety monitoring and evaluation of construction projects.
Network community partition based on intelligent clustering algorithm
Authors:   Information Engineering College, Henan University of Animal Husbandry and Economy, Cai Z.M.
Published: December 2020

The division of network community is an important part of network research. Based on the clustering algorithm, this study analyzed the partition method of network community. Firstly, the classic Louvain clustering algorithm was introduced, and then it was improved based on the node similarity to get better partition results. Finally, experiments were carried out on the random network and the real network. The results showed that the improved clustering algorithm was faster than GN and KL algorithms, the community had larger modularity, and the purity was closer to 1. The experimental results show the effectiveness of the proposed method and make some contributions to the reliable community division.
The study of skeleton description reduction in the human fall-detection task
Authors:   Tula State University, Seredin O.S. , Kopylov A.V. ,   Tula State University, Surkov E.E. ,   Tula State University
Published: December 2020

Accurate and reliable real-time fall detection is a key aspect of any intelligent elderly people care system. A lot of modern RGB-D cameras can provide a skeleton description of a human figure as a compact pose presentation. This makes it possible to use this description for further analysis without access to real video and, thus, to increase the privacy of the whole system. The skeleton description reduction based on the anthropometrical characteristics of a human body is proposed. The experimental study on the TST Fall Detection dataset v2 by the Leave-One-Person-Out method shows that the proposed skeleton description reduction technique provides better recognition quality and increases the overall performance of a Fall-Detection System.
Analytical design of refractive optical elements generating a prescribed two-dimensional intensity distribution
Authors:   IPSI RAS – Branch of the FSRC “Crystallography and Photonics” RAS, Byzov E.V. , Doskolovich L.L. ,   IPSI RAS – Branch of the FSRC "Crystallography and Photonics" RAS; Samara National Research University,   Samara National Research University, Kravchenko S.V. ,   IPSI RAS – Branch of the FSRC “Crystallography and Photonics” RAS, Kazanskiy N.L. ,   IPSI RAS - Branch of the FSRC “Crystallography and Photonics” RAS,   Samara National Research University
Published: December 2020

A new source-target mapping for the design of refractive optical elements generating prescribed 2D intensity distributions is proposed. The calculation of the optical element is reduced to the solution of ordinary explicit differential equations. The simulation results presented demonstrate high performance of the proposed method. While generating uniform rectangular intensity distributions with angular dimensions varying from 80°×1° to 40°×20°, the normalized root-mean-square deviations between the generated and required distributions do not exceed 15 %.
Du spécifique au générique dans la détermination du mot souffrance dans Salvifici doloris de Jean-Paul II : Analyse contrastive français-arabe
Authors: El Kak Manar
Published: December 2020

Od użycia szczegółowego do ogólnego określnika wyrazu souffrance w Salvifici doloris Jana Pawła II: analiza konrastywna francusko-arabska

Celem artykułu jest wykazanie, w jaki sposób dokonuje się przejście od użycia szczegółowego do ogólnego określnika wyrazu souffrance, pojawiającego się w strukturze: souffrance + N lub N de la souffrance, w Salvifici doloris Jana Pawła II. Analiza wyrazu souffrance i jego tłumaczenia jest przeprowadzana w perspektywie kontrastywnej francusko-arabskiej według dwóch parametrów: rodzajnik i kategoria liczby. W wyniku tej analizy ujawnia się kilka typów tłumaczenia wyrazu souffrance. Tak więc tłumaczenie souffrance de l’homme ma kilka różnych wartości w zależności od tego, czy jest wyrażone za pomocą struktur rzeczownik + rzeczownik ʾalam-u al-ʾinsān-i, rzeczownik + przymiotnik ʾalam-un bašarīyy-un, bądź za pomocą zdania czasownikowego z komponentem pasywnym. Ponadto w języku arabskim w przeciwieństwie do francuskiego brak rodzajnika w liczbie mnogiej zmusza rzeczownik do przekształcenia siebie samego w liczbę mnogą. W konsekwencji w tłumaczeniu francuskiej liczby pojedynczej ogólnej na arabski większość rzeczowników jest wyrażona w liczbie mnogiej, zwłaszcza w tłumaczeniu la souffrance du Christ, akcentując w ten sposób różnorodność w jedności.

Du spécifique au générique dans la détermination du mot souffrance dans Salvifici doloris de Jean-Paul II : Analyse contrastive français-arabe

L’objectif de cette étude consiste à démontrer comment s’opère le passage du spécifique au générique dans la détermination du mot souffrance engagé dans une construction d’annexion : souffrance + N, ou N + de la souffrance, dans Salvifici Doloris de Jean-Paul II. L’étude examine la traduction du mot souffrance dans une perspective contrastive français-arabe, par le biais de deux paramètres : l’article et la catégorie du nombre. L’analyse révèle la présence de plusieurs types de traduction du mot souffrance. Ainsi, la traduction de la souffrance de l’homme possède différentes valeurs selon qu’elle est rendue par un : nom + nom alam al-insān, nom + adjectif alam bašariyy, ou par une phrase verbale avec une nuance de passivité. Par ailleurs, en arabe, et contrairement au français, l’absence d’un article-pluriel oblige le nom à se transformer lui-même au pluriel. Par conséquent, pour traduire le singulier générique français en arabe, la plupart des noms sont rendus par un pluriel, notamment dans la traduction de la souffrance du Christ, accentuant ainsi la diversité sous l’unité.
The Interpreting Portfolio as a Self-Regulation Tool in Interpreter Training: Preliminary Findings from a Pilot Study
Authors: Mirek Joanna
Published: December 2020

Portfolio jako narzędzie samoregulacji w kształceniu tłumaczy konferencyjnych: wstępne wnioski z badania pilotażowego

Z uwagi na to, że od profesjonalnych tłumaczy konferencyjnych oczekuje się autonomicznego rozwoju, zadaniem dydaktyków przekładu powinno być przygotowywanie początkujących tłumaczy do rozwoju zawodowego po ukończeniu edukacji formalnej. Jedną z najtrafniejszych koncepcji w tym kontekście jest pojęcie samoregulacji, opisane przez Barbarę Moser-Mercer. Wdrożenie elementów samoregulacji, tj. refleksji nad procesem tłumaczenia oraz poczynionych postępów, praca nad jakością przekładu oraz rozwijanie praktyk profesjonalnego tłumacza konferencyjnego może być ułatwione przez wprowadzenie „indywidualnie dopasowanego narzędzia” (Kiraly  49), umożliwiającego rozwój zarówno w edukacji uniwersyteckiej, jak i po ukończeniu studiów. Niniejszy artykuł przedstawia koncepcję portfolio jako narzędzia wspierającego samoregulację u początkujących tłumaczy konferencyjnych, które umożliwia im dokumentowanie i ocenianie poczynionych postępów, rozwijanie skutecznych strategii umożliwiających dążenie do wyznaczonych celów oraz skłania do refleksji nad procesem przekładu. Otrzymane wyniki oraz pozytywne reakcje zwrotne od studentów biorących udział w badaniu pilotażowym wskazują na wysoką efektywność portfolio w zakresie rozwoju umiejętności samoregulacyjnych u adeptów przekładu konferencyjnego.
Sprawność czytania w praktyce nauczania języka polskiego jako obcego (na przykładzie języka biznesowego)
Authors: Oczko Paulina
Published: December 2020

W artykule została poruszona kwestia rozwijania sprawności czytania w materiałach do nauczania polskiego języka biznesowego. Przeprowadzone analizy bardzo wyraźnie pokazują, że teksty zawarte w podręcznikach stanowią głównie bazę do nauczania gramatyki. Ponadto brakuje koncentracji na sprawności czytania jako umiejętności językowej samej w sobie. Nauczaniu języków specjalistycznych przyświeca idea podejścia komunikacyjnego (tę tendencję można dostrzec w nowszych podręcznikach do nauki języka biznesowego). Prowadzi to do konkluzji, że w praktyce glottodydaktycznej nauczanie języka biznesu nie różni się znacząco od nauczania języka ogólnego, w obu przypadkach stosowane są te same metody dydaktyczne.
Foreign-Space Dramatization in Graham Greene’s The Power and the Glory: Revisiting Greeneland
Authors: Valverde Beatriz
Published: December 2020

Dramatyzacja obcej przestrzeni w powieści Moc i chwała Grahama Greene’a: Ponowna wizyta w Greeneland

Graham Greene często podróżował i akcja jego książek często ma miejsce w różnych zakątkach świata. Mimo to krytycy są zgodni, że w swych powieściach Greene stworzył a-topos – przestrzeń odzwierciedlającą rozwój tematów (czy to duchowych, czy politycznych) zajmujących autora, a nie konkretne rzeczywiste miejsce. Z czasem ów a-topos otrzymał nazwę Greeneland. Niniejszy artykuł stawia tezę, że krytycy, skupiając się na głównych motywach w twórczości Greene’a, ignorują fakt, że dokładna analiza świata przedstawionego podważa powszechnie panujące przekonanie, jakoby Greene wykreował w swojej twórczości przestrzeń mentalną, nie-miejsce. W celu dowiedzenia postawionej tezy, artykuł analizuje reprezentację przestrzeni i społeczeństwa w Mocy i chwale (1940), powieści, której akcja toczy się podczas religijnych prześladowań w Meksyku w latach dwudziestych dwudziestego wieku. Porównuję utwór Greene’a z powieścią Pedro Páramo Juana Rulfo (1955), gdyż powieść ta opisuje ten sam okres, a krajobrazy w niej opisane przypominają te z powieści Greene’a. Tym samym artykuł proponuje redefinicję idei Greeneland.
The Concept of the Edge in the Plays of Marina Carr
Authors: González Chacón María Del Mar
Published: December 2020

Pojęcie krawędzi w sztukach Mariny Carr

Kobiety w sztukach Mariny Carr zawsze są na krawędzi. Mai cierpi z powodu braku indywidualności i próbuje odrzucić ograniczenia narzucone przez rodzinę, Portia walczy o prawo do bycia matką która nie kocha swoich dzieci, Hester nie potrafi żyć poza trzęsawiskiem, które ją zabija, a Catherine próbuje żyć we śnie. Krawędź w sztukach Mariny Carr można zdefiniować jako przestrzeń umysłu, przestrzeń oporu w której bohaterki próbują zamieszkać. Krawędź oznacza margines na którym kobiety odnajdują własną przestrzeń. W późniejszych sztukach Mariny Carr mitologiczne, wiejskie krajobrazy ustępują miejsca współczesności. Przestrzenie miejskich napięć i konfliktów tworzą krawędzie, które są bardziej widoczne w przestrzeni dramatu, a transformacje dokonują się poprzez prowokacyjne dialogi i zachowania, wskazujące na nowe pojęcie krawędzi na której kobiety nadal poszukują swojego miejsca.
The Genii Locorum as the Necessary Space and Place for Human Development
Authors: Kłos Jan
Published: December 2020

Genii locorum jako konieczna przestrzeń i miejsce ludzkiego rozwoju

Głównym tematem tego tekstu jest znana postać wiktoriańska, John Henry Newman (1801–1890) oraz sposób, w jaki odpowiadał na swój etos. Zakłada się tutaj, że każda osoba wzrasta w konfrontacji z miejscem, w którym żyje. Miejsce to, nasz genius loci, wywiera wpływ na nasze decyzje. Najważniejszą rzeczą jest odkryć system, który to miejsce tworzy. Miejsce to może być prawdziwe lub fałszywe. Newman wysoko cenił sobie swój dom rodzinny, przyjaźni uniwersyteckie oraz Kościół jako ostateczny cel życiowej podróży. Urodził się w Kościele anglikańskim, kiedy to środowisko anglikańskie było szczególnie wrogo nastawione do katolików rzymskich. Jego osobista historia jest tak fascynująca, ponieważ pomimo wrogo nastawionego otoczenia, potrafił przewartościować własne życie.