bluuebunny/crossref_metadata_2025 huggingface dataset:
THE EXCESSIVE USE OF SOCIAL MEDIA AND ITS RELATIONSHIP TO INSOMNIA AMONG NURSING STUDENTS
Authors: Siregar Deboorah , Adellia Adellia , Harefa Alserina Hideni , Oriza Yonavia , Siregar Deborah , Hutasoit Elissa
Published: October 2021

Social media is online media used to interact and exchange information with other people. Excessive use of social media can negatively impact, one of which can make a person's sleep patterns change, causing insomnia. Insomnia is a condition characterized by a disturbance in the amount, quality, or time of an individual's sleep. This study aimed to analyze the relationship between the excessive use of social media and insomnia among nursing students. This research method was correlational quantitative with a cross-sectional design. The sampling technique used was purposive sampling with a sample size of 207 participants. Data analysis used the chi-square test.The results showed 102 participants (49.3%) actively used social media, and 105 participants (50.7%) were not actively using social media, 103 participants (49.8%) experienced insomnia, and 104 participants (50.2%) do not experience insomnia. This study demonstrated a significant relationship between the excessive use of social media and insomnia among nursing students(p-value 0.01).Therefore, this research can provide information to students to optimize the use of social media to support the learning process and improve students’ sleep quality.
SELF CARE ABILITY INFLUENCES THE QUALITY OF LIFE CONGESTIVE HEART FAILURE (CHF) PATIENTS
Authors: Febtrina Rizka , Putri Elisa Mardika , Malfasari Eka
Published: October 2021

The prevalence of congestive heart failure sufferers in Indonesia is very high and is expected to continue to increase every year. Heart failure conditions and other manifestations cause a decrease in the quality of life due to the patient's inability to perform self-care properly. The purpose of this study was to determine the relationship between self-care ability and the quality of life of patients with congestive heart failure (CHF) in cardiac outpatient unit Arifin Achmad Hospital, Riau Province. This research was conducted on 64 respondents which by purposive sampling technique. Methode of this research was descriptive correlative with cross-sectional disign. The instrument of this research is the Self Care of Heart Failure Index (SCHFI) questionnaire to measure self-care ability and  Minnesota  Living  with  Heart  Failure  Questionnaire (MLHFQ)  questionnaire  to measure quality of life. The results of this study indicate that the respondent's self-care ability is balanced by good and bad as many as 32 respondents (50.0%)   and the quality of life of the majority is bad as many as 39 respondents (60.9%). Based on the chi square test it can be concluded that p value= 0.01 (<0.05) means that there is a significant relationship between self-care ability and the quality of life of people with congestive heart failure (CHF). The recommendation for further research is to study about the factors that influence self-care ability and quality of life in patients with congestive heart failure.
PENGARUH DENSITAS ARUS TERHADAP PERILAKU RETAK BETON BERTULANG YANG MENGALAMI KOROSI TULANGAN
Authors: Amalia Zahra , Saidi Taufiq , Saidi Taufiq , Aulia Teuku Budi , Aulia Teuku Budi , Mahlil Mahlil , Mahlil Mahlil
Published: October 2021

Abstrak

 

Korosi pada struktur beton betulang dapat mengurangi kinerja struktur dan umur layannya karena volume tulangan yang berkurang. Besarnya jumlah korosi yang dipengaruhi oleh laju korosi dapat digambarkan melalui besarnya densitas arus yang terjadi. Jumlah korosi yang terjadi mempengaruhi perilaku retak pada beton bertulang, oleh karen itu, pada studi ini dilakukan uji eksperimental untuk mengevaluasi pengaruh densitas arus terhadap perilaku retak permukaan beton dari struktur beton bertulang yang mengalami korosi tulangan. Pengujian dilakukan dengan mengaplikasikan variasi densitas arus yaitu 900 µA/cm2, 500 µA/cm2, 200 µA/cm2 and 100 µA/cm2 pada pengujian korosi secara elektrik menggunakan larutan NaCl sebagai elektrolit untuk menghasilkan ion Cl-. Benda uji yang digunakan adalah balok dengan luas penampang 150x150 mm2 dan panjang benda uji 300 mm. Tulangan baja diameter 19 mm digunakan pada tengah penampang. Hasil pengujian menunjukkan bahwa perilaku retak dari beton bertulang yang mengalami korosi pada tulangannya memiliki kurva yang bilinear. Selain itu, hasil pengujian menunjukkan bahwa densitas arus yang rendah memiliki kecepatan retak permukaan beton yang lebih tinggi jika dibandingkan dengan benda uji dengan menggunakan densitas arus yang tinggi.

 

Kata kunci: korosi, beton bertulang, produk korosi, retak, densitas arus

 

Abstract

 

Corrosion in reinforced concrete structure can reduce structure performance and its service life due to rebar mass loss. Corrosion amount influenced by corrosion rate can be figured out by using current density. Corrosion amount influences the crack behavior of reinforced concrete, therefore, in this study, experimental study was performed to evaluate the effect of current density to surface concrete cracking behavior of corroded reinforced concrete structure. Accelerated corrosion test tests were conducted with various current density. It was 900 µA/cm2, 500 µA/cm2, 200 µA/cm2 and 100 µA/cm2. NaCl solution was used as electrolyte to produce ion Cl-. The specimens were beam with cross section area 150x150 mm2 and 300 mm in length. Rebar with diameter 19 mm was applied in the center of specimen. The results showed that cracking behavior of corroded rebar has bilinear curve that shows the effect of corrosion products movement through cracks. Furthermore, lower corrosion rate has higher cracking speed than higher corrosion rate.

 

Keywords: corrosion, reinforced concrete, corrosion products, cracking, current density
KESIAPAN ADOPSI BUILDING INFORMATION MODELING (BIM) PADA KONSULTAN PERENCANA DI KOTA PALEMBANG
Authors: Fitriani Heni , Br Bangun Wina Prasetio
Published: October 2021

Abstrak

 

Salah satu industri yang memfokuskan pada pengembangan infrastruktur adalah industri Architecture Engineering and Construction (AEC). Penggunaan berbagai teknologi dan aplikasi Building Information Modeling (BIM) pada sektor konstruksi semakin meningkat. Penelitian ini bertujuan untuk mengetahui tingkat kesiapan pelaku AEC khususnya konsultan perencana dalam proses adopsi BIM. Penelitian ini menggunakan survei kuesioner dengan mengumpulkan data dari 96 responden pada perusahaan konsultan di Palembang. Dari hasil analisa didapat bahwa hampir semua responden telah mengetahui istilah BIM dan tingkat kesiapan dalam mengadopsi BIM dengan nilai rata-rata sebesar 3,187 yang berarti bahwa kesiapan konsultan perencana di Kota Palembang dinyatakan cukup siap dalam mengadopsi BIM. Adapun 3 hambatan utama dalam mengadopsi BIM menurut penelitian ini yaitu tingginya biaya investasi awal; terlalu nyaman dengan budaya kerja lama; dan kurangnya pengetahuan mendalam terkait BIM, oleh karena itu penggunaan BIM pada industri konstruksi harus ditingkatkan dengan penguatan regulasi oleh pemerintah. Peranan kesadaran perusahaan dan individu di dalamnya serta ketegasan pemerintah  akan menentukan tingkat perkembangan BIM.

 

Kata kunci: Adopsi, digitalisasi, Building Information Modeling, AEC

 

 

Abstract

 

One of the industries focusing on infrastructure development is Architecture Engineering and Construction (AEC) industry. The use of technology and Building Information Modeling (BIM) in construction sector has been widely increased. This research aimed to identify the readiness level of design consultants on BIM adoption. This research used a questionnaire survey to collect data from 96 respondents of consultant firms in Palembang. Based on the analysis, it was found that almost all respondents were already familiar with BIM term and the level of readiness in adopting BIM had a mean average value of 3.187, indicating that the respondents were quite ready in adopting BIM. The three main barriers in adopting werethe high investment cost; being too comfortable with the conventional work culture; and lack of knowledge about BIM. Therefore, the use of BIM in the construction industry must be increased by strengthening regulations conducted by the government. The role of corporate, individual awareness and government involvement will determine the level of BIM development.

 

Keywords: Adoption, digitalization, Building Information Modeling, AEC

 
Satisfacción de habitabilidad durante el confinamiento por Covid-19.
Authors: Ramos Sanz Alba Inés
Published: October 2021

Mediante la realización de una Investigación Empírica de tipo Descriptivo, se espera determinar el grado de satisfacción de los usuarios residenciales con su hábitat, estimando oportuno para la recopilación de información el escenario atípico de confinamiento social, en su instancia más estricta. El presente trabajo se basa en un estudio comparativo de dos tipologías residenciales: la vivienda unifamiliar y el departamento. A través de una encuesta electrónica estructurada se obtienen datos referidos a las condiciones de habitabilidad de los usuarios de dichas tipologías, durante el período inicial de la cuarentena. Las respuestas procesadas revelan indicadores de insatisfacción comunes de los encuestados respecto de la amplitud, dimensiones, localización, confort del hábitat que se perciben en período de cuarentena. Estos resultados grafican un instante de corte transversal de la interacción del habitante con su espacio habitable, siendo de utilidad para advertir a los organismos encargados de diseñar políticas y/o a los profesionales de la construcción sobre necesidades insatisfechas o disconformidades y tendencias emergentes del hábitat de espacios físicos residenciales y su inserción urbana, que podrían en la actualidad y en el corto plazo entrar en conflicto con las tendencias del mercado inmobiliario residencial.
Regularización y mercado de suelo urbano en asentamientos irregulares.
Authors: Leal-Iga Carlos , Cedillo Salazar María Teresa
Published: October 2021

El mercado del suelo urbano en polígonos con asentamientos irregulares ha sido estudiado desde varias perspectivas, sin embargo, las dificultades para entender los motivos que fundamentan el vivir en ambientes sin las condiciones urbanas adecuadas no han sido resueltas. Este artículo tiene por objetivo general estudiar los factores que determinan la decisión de los posesionarios de ocupar el espacio, y en lo particular se analiza el caso de estudio de la zona denominada Cima de la Loma ubicada en la parte alta del área central de la ciudad de Monterrey, México. Se utilizó como metodología el análisis georreferenciado de información de los pobladores, la visita al campo en conjunto con autoridades para recorrer la zona, así como la aplicación del método de regresión logística binaria a las variables de interés. El resultado obtenido indica que hay una tendencia a regularizar los predios de los posesionarios en la medida en que sean mejor sus condiciones de accesibilidad en cuanto a condiciones físicas del espacio y estado físico de los habitantes, y de los factores de la población, el convivir en hogares y la mejor preparación escolar tienden a fomentar la decisión de los posesionarios a la regularización.
El espacio urbano y sus procesos de expansividad adyacente.
Authors: Sousa-González Eduardo
Published: October 2021

La evidencia empírica indica, sobre la forma en que el espacio urbano y en particular las zonas metropolitanas avanzan inexorablemente en el territorio, en múltiples casos sin un control eficiente, efectivo y eficaz, expandiendo constantemente sus límites físicos perimetrales hacia una orientación periférica del centro urbano; un sometimiento de facto en este proceso evolutivo transformacional que va de lo no-urbano (rural, periurbano), a lo urbano-metropolitano (ciudad-metrópoli); no solo a la naturaleza originaria adyacente al lugar, sino también a todos los componentes que sobre ella se asientan y transitan: desde los diferentes grupos sociales originarios ahí radicados, que han desarrollado patrones específicos: identitarios, culturales, idiosincráticos, de hábitos y costumbres, las cuales se han cimentado a lo largo de sus vivencias cotidianas en el lugar; hasta la modificación de las formas edilicias de edificación y de las maneras de la utilización de los materiales para la construcción in situ. Requiriendo para ello inevitablemente la devastación y en múltiples casos, la aniquilación de la naturaleza originaria…
Phonecardoperated payphones in buses in Brazil
Authors: Tavares Wagner de Souza
Published: October 2021

Payphones were installed in public buses in Brazil. These payphones worked with same phonecards used in tradicional payphones or with specific phonecards produced by telecommunication companies in collaboration with bus transport companies. The objectives of this study were to identify the buses installed with payphones in Brazil, chronology, payphone system, and phonecard type (whether tradicional or specific). The specific phonecards were described. A mobile phone-type payphone working with tradicional phonecards, developed by Telecomunicações da Paraíba S.A. (TELPA; João Pessoa, Paraíba State, Brazil) and installed in 1994 on Rogetur Transporte e Turismo Ltda. transport company buses, is the first consolidate case of a payphone used in a bus in Brazil. Specific phonecards developed by Globalstar, Inc. (Covington, Louisiana, United States of America) in 2000 were used in payphones installed on Viação Itapemirim S.A. and Empresa de Ônibus Nossa Senhora da Penha S.A. transport company buses.
Desafios e práticas no âmbito de um laboratório universitário de fabricação digital em apoio a prática artística
Authors: Henno Juliana , Guerra Priscila , Tavares Monica , Yamanoi Marcelo , Medina Carol
Published: October 2021

Em um espaço de dez anos, laboratórios de fabricação digital – inicialmente dedicados a engenharia e desenho industrial – vêm se proliferando e ampliando sua abrangência para áreas diversas em que a prática experimental como meio para criação é elemento focal. Enquanto alguns destes laboratórios permitem o acesso livre a seus equipamentos ou, de modo diverso, são privados, outros são exclusivamente voltados para o suporte a atividades universitárias. O presente artigo tem por finalidade destacar a relevância da implantação de laboratórios de fabricação digital para o ensino, pesquisa e extensão, em contexto artístico acadêmico, com apresentação de caso específico do ModelaFab, Laboratório de Modelagem e Fabricação Digital do Departamento de Artes Plásticas da Escola de Comunicações e Artes da Universidade de São Paulo (ECA-USP). Em primeiro lugar, apresentaremos os desafios decorrentes da implementação de um laboratório universitário de fabricação digital; em segundo lugar, exporemos o processo de instalação do ModelaFab, sua estrutura e as atividades nele desenvolvidas até 2019.
Reaproveitamento de resíduos – um estudo de caso sobre pesquisas da linha Design
Authors: Gomes Mayara Maluf , Santos Wener Miranda Teixeira dos , Santos Denilson Moreira
Published: October 2021

Este artigo busca refletir sobre a importância das pesquisas em design voltadas para sustentabilidade e inovação social, tendo como objetivo a ênfase no estudo de materiais, especificamente no reaproveitamento de resíduos, a partir de pesquisas realizadas no Programa de Pós-Graduação em Design (PPGDg) da Universidade Federal do Maranhão (UFMA) na Linha de Materiais, Processos e Tecnologia. A metodologia utilizada aciona a revisão de literatura e o estudo de caso que explanará 3 dissertações desenvolvidas no PPGDg (UFMA), visando um maior embasamento teórico sobre o reapro- veitamento de resíduos no setor da construção civil. Nas considerações finais houve a elaboração de uma tabela que contém os autores e títulos das pesquisas desenvolvidas no PPGDg (UFMA) ao longo dos últimos anos com foco em materiais, visando auxiliar novos pesquisadores e/ou entusiastas do assunto.
Experimentos no campo do design – reflexões sobre a linha de pesquisa Design
Authors: Rodrigues Pedro Paulo Bezerra , Noronha Raquel Gomes
Published: October 2021

Este artigo apresenta estudos recentes da linha de pesquisa Design: Materiais, Processos e Tecnologia, que faz parte do curso de Mestrado em Design do Programa de Pós-Graduação em design da Universidade Federal do Maranhão – UFMA. As pesquisas aqui demonstradas têm em comum a realização de experimentações de design, que diferem da definição clássica de experimento científico e se aproximam dos preceitos do design research, amparados pelo design participativo e pelas práticas do design anthropology, de forma a aproximar os sujeitos de pesquisa, entendendo-os como copesquisadores. Três estudos foram revisados e a análise dos mesmos contribui no entendimento do das possibilidades e das fronteiras do método experimental de design.
Pesquisa, Design e Ergonomia
Authors: Diniz Raimundo Lopes , Lima André Luís de Oliveira , Viana Thiscianne Mesquita
Published: October 2021

O presente artigo pretende descrever a criação, implantação e contexto atual da linha de pesquisa “Design: ergonomia e usabilidade de produtos e sistemas”, como parte do processo de consolidação do Programa de Pós-Graduação em design, da Universidade Federal do Maranhão, em seu panorama histórico. Apresentam-se sua definição e objetivo, além de todos os elementos constituintes da sua conformação (estrutura curricular, docente vinculados, dissertações defendidas, laboratórios e grupos de pesquisa).
Identificando Potenciais Preditores de Replicabilidade de Experimentos na Iniciativa Brasileira de Reprodutibilidade
Authors: Fernandes Nathalia Raquel de Souza , GOULART RICARDO NETTO , LINHARES JIMMY GLEDSON HAYDEN PONTES , Neves Kleber , Amaral Olavo
Published: October 2021

A credibilidade dos achados científicos vem sendo analisada nos diversos campos da ciência ao longo dos últimos anos (Forsell, et al. 2019). Entre vários projetos de replicação sistemática, a Iniciati
Significado de Medellín para a Igreja católica na América Central
Authors: Meléndez Guillermo
Published: October 2021

O passado compartilhado, a história vivida em comum impõe ao termo “Centroamérica” (América Central) uma definição que se restringe a cinco países: Guatemala, EI Salvador, Honduras, Nicarágua e Costa Rica. O território tem uma superfície de 419 mil km2, o que significa 2% da superfície latino-americana. Por outro lado, seus aproximadamente 22 milhões de habitantes equivalem a 6% de toda a população da América Latina...
Changes in the spectrum of protein components and the concentration of phospholipids of the erythrocyte membrane in patients with ulcerative colitis
Authors: Sai O. V. , Pivovarov Yu. I. , Dmitrieva L. A. , Sergeeva A. S.
Published: October 2021

Ulcerative colitis is a chronic inflammatory bowel disease with unclear etiology. An insufficient amount of data on the etiopathogenetic mechanisms of the disease creates opportunities to research them at the cellular level, including the membrane level. Since the functional state of the cytoplasmic membrane largely depends on protein-lipid interactions, we studied the effect of the proportional ratio of three proteins (glucose transporter, glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and glutathione-S-transferase (GST)) on the level of phosphatidylethanolamine and phosphatidylcholine in the erythrocyte membrane of patients with ulcerative colitis during an acute attack. The study involved 51 patients with ulcerative colitis during the acute attack and 26 clinically healthy individuals. The groups are comparable by gender and age to study the proteins of the cytoplasmic membrane, Laemmli electrophoresis technique in polyacrylamide gel was used, followed by an assessment of the intensity of protein bands staining on electropherograms. Phospholipid fractions were obtained using thin-layer chromatography and their content was assessed using the Mathcad 2001 Professional system. Statistical processing was carried out by the program Statistica 10.0 for Windows. Changes of phosphatidylcholine and phosphatidylethanolcholine levels in patients and healthy individuals are not of the same type and are interrelated with changes in the proportion of membrane proteins of the glucose transporter, GAPDH and GST. The proportions of proteins that affect the level of phospholipids have calculated. In patients with ulcerative colitis, a decrease in the level of the studied membrane lipids have revealed in comparison with the clinically healthy group, in addition, an increase in the proportion of the glucose transporter and a decrease in the proportion of GST have noted. In addition, the relationship between an increase in the level of the cytoplasmic membrane phospholipids in ulcerative colitis and a change in the proportion of GAFDH in a smaller direction, which slows down the process of glucose oxidation, was determined. The obtained data confirm the strengthening of the processes of antioxidant protection and the increased need for energy supply of the cell membrane in patients with ulcerative colitis during an acute attack.
Historical aspects of the problem of treatment of trigeminal neuralgia and the role of neurosurgical methods in its solution (literature review)
Authors: Zhurkin A. N. , Semenov A. V. , Sorokovikov V. A. , Bartul N. V.
Published: October 2021

The trigeminal nerve is a mixed fifth cranial nerve, consisting of motor and sensory components. The sensitive component receives somesthetic information from the skin and mucous membranes of the face into the central nervous system, and the motor component is responsible for the innervation of chewing muscles. One of the manifestations of the pathology of the trigeminal nerve is pain syndrome. Trigeminal neuralgia occupies the main place among neurogenic pain syndrome in the face, is characterized by а severe course and the absence of sufficiently effective methods of treatment. According to the World Health Organization (WHO), the prevalence of trigeminal neuralgia in different countries is 2–5 cases per 100 thousand people per year. Trigeminal neuralgia is classified into 3 etiologic categories. Idiopathic trigeminal neuralgia occurs without apparent cause. Classical trigeminal neuralgia is caused by vascular compression of the trigeminal nerve root. Secondary trigeminal neuralgia is the consequence of a major neurologic disease, e. g., a tumor of the cеrеbеllоpоntine angle or multiple sclerosis. Today, there are many different options for the surgical treatment of trigeminal neuralgia. microvascular decompression of the root, radiosurgical destruction of the Gasser’s node, radiofrequency destruction, glycerol rhizotomy, balloon microcompression are considered the main effective and proven surgical methods for treating trigeminal neuralgia. But the questions of diagnosing the cause of the disease and choosing an adequate surgical method for treating therapeutically resistant trigeminal neuralgia for a particular patient remain open. The development of surgical methods begins from ancient times to the present day. The main stages in the development of neurosurgical treatment methods are presented. The following surgical techniques are described: open method – microvascular decompression, and closed percutaneous destructive methods – radiofrequency destruction, glycerol rhizotomy, balloon compression, radiosurgery, cryodestruction, laser destruction, botulinum toxin injections.
Clinical case of combined diabetes insipidus and cerebral salt-wasting syndrome in a patient with craniocerebral and spinal injury
Authors: Ivanova A. A. , Lebedeva M. N. , Pervukhin S. A. , Abysheva Yu. V.
Published: October 2021

Introduction. Cerebral salt-wasting syndrome and diabetes insipidus are serious complications of craniocerebral injury and spinal cord injuries. Each of the syndromes in some cases causes a life-threatening condition. This determines the importance of timely diagnosis and emergency intensive care measures. In the literature, there are only single descriptions of combinations of these symptoms in one patient.Clinical case report. A victim with craniocerebral injury and cervical spinal cord injury underwent, according to emergency indications, emptying and drainage of a tense subgaleal hematoma of the fronto-parieto-occipital region, spinal cord decompression, and stabilization of the spine. Postoperative follow-up and intensive care: on the 1st day the rate of diuresis was 2.5 mL/kg/h, blood glucose level – 14.18 mmol/L, and sodium level – 148–158 mmol/L. The patient was diagnosed with diabetes insipidus, and a therapy with desmopressin at a dose of 0.6 mg/day, restoration of fluid volume with hypotonic solutions, and correction of hyperglycemia was started. On the 4th day blood sodium level was 133 mmol/L, and blood glucose level – 8.67 mmol/L. On the 5th day, hyponatremia of 126–115 mmol/L was noted with a diuresis rate of 4 mL/kg/h and glicemya level of 7.86 mmol/L. The development of cerebral salt-wasting syndrome was diagnosed, and the infusion of hydrocortisone 400 mg/day and of 10% NaCl solution was started. On the 6th day glucose level returned to normal. On the 9th day of follow-up, an increase in the volume of diuresis was again observed, and desmopressin therapy was continued. Stable normalization of water-electrolyte balance, urine output, and glucose levels were observed on the 16th day of follow-up.Conclusion. Monitoring of fluid balance and electrolyte composition of blood serum, and adequate replacement therapy were the conditions for successful treatment of a rare combination of diabetes insipidus and cerebral salt-wasting syndrome in patients with concomitant craniocerebral and spinal cord injuries.
Dietary intake in indigenous adolescents in rural Buryatia, Russia
Authors: Rychkova L. V. , Dolgikh O. A. , Pogodina A. V. , Аstakhova T. A. , Ayurova Zh. G.
Published: October 2021

Background. The diet of adolescents is an important factor in their future health. The diet is formed under the influence of biological, personal, family, socio-economic, environmental, and cultural factors.The aim: to study the diet of adolescents in rural areas of Buryatia and compare the dietary intake of the Russian and Buryat ethnic groups.Materials and methods.The study included 92 rural adolescents 11–17 years old (44 boys, 48 girls); 49 of them were Buryats, 43 – Russians. Dietary intake was assessed by the food record method. The intake of energy, macronutrients (proteins, fats and carbohydrates) and micronutrients (major groups of vitamins and trace elements) of the diet was determined. The values obtained were compared with references to daily energy and nutrient intake, and between groups of adolescents of different ethnicity.Results.The diets of rural adolescents were not balanced. Only 7.6 % of adolescents include fish in their diet. Milk and dairy products are consumed by 38 % of the respondents. Daily energy intake was significantly lower the recommended guidelines. The diet is characterized by a deficiency of vitamins of groups A, C, and D, group B (with the exception of cobalamin), niacin, biotin, essential trace elements (calcium, phosphorus, iodine), high sodium intake. A significant deficiency of dietary fiber has been noted. The Buryats showed a shift in the ratio of proteins, fats and carbohydrates in the diet towards carbohydrates (1 : 1.2 : 5.3).Conclusion.The results indicate significant disturbances in the composition of the diet in rural adolescents in Buryatia, more pronounced in the Asian subgroup. This can be a rationale for the development of targeted nutrition monitoring programs aimed at preserving the health of the youth.
Predictive risk factors for the development of diseases with lymphoproliferative syndrome in children
Authors: Makhmutov R. F.
Published: October 2021

Background. Harmful environmental factors and negative social trends have an adverse effect on the adaptive resources of the child’s body, which in combination reduces the health index in the child population. An ambiguous epidemiological situation, an increase in morbidity rates in children, a variety of clinical manifestations of Epstein – Barr viral infection, recurrent respiratory diseases, adenovirus infection complicate their differential diagnosis in the early stages. In this regard, the assessment of risk factors and early prognosis of the development of primary form of Epstein – Barr viral infection (EBVI), recurrent respiratory diseases (RRD), adenovirus infection (ADVI) in children is an urgent task.The aim: to study the significance of risk factors influencing the development of diseases with lymphoproliferative syndrome in children.Materials and methods. Clinical and laboratory examination and analysis of case histories of 336 children and adolescents held with diseases with lymphoproliferative syndrome. Data from 30 apparently healthy children and adolescents of the same age were used as a comparison group. The Bayesian method with sequential Wald analysis was used to assess risk factors. ROC-analysis was used to check the adequacy of the forecasting models. The quality of the built models was evaluated by their sensitivity and specificity.Results. It has been established that predictors of diseases with lymphoproliferative syndrome in children are intrauterine fetal hypoxia, low or, on the contrary, high birth weight, neonatal jaundice, low Apgar score, as well as maternal factors (somatic pathology and SARS during pregnancy, gestosis, gestational anemias, young or mature age of the pregnant women). Additional predictors of the development of this pathology can be considered a decrease in the indicator of the cell-phagocytic potential to 337.1 ± 2.3 CU, a decrease in the immune-lymphocytic potential to 237.0 ± 8.2 CU, an increase in the load-erythrocyte coefficient to 0.67 ± 0.03 CU and a decrease in the leukocyte index of intoxication to 0.40 ± 0.05 CU.Conclusion. The combination of clinical and anamnestic factors with indicators of general reactive potential increases the integral general informative value of the prognostic model. The accounting by specialists of the general medical and preventive network of the identified predictors of the development of diseases with lymphoproliferative syndrome will contribute to the timely diagnosis of the primary form of Epstein – Barr viral infection, recurrent respiratory diseases and adenovirus infection in children.
Metabolic syndrome: Epidemiology, diagnostic criteria, racial characteristics
Authors: Vilson N. I. , Belenkaya L. V. , Sholokhov L. F. , Igumnov I. A. , Nadelyaeva Ya. G. , Suturina L. V.
Published: October 2021

Metabolic syndrome (MS) is a very serious pathological condition that occurs in the clinical practice of doctors of various specialties. Often, the presence of MS aggravates the course of comorbidities, while various diseases can serve as a risk factor for its development. The significant prevalence of MS determines the need for its early diagnosis for timely correction and prevention of its long-term complications.The aim. To systematize data on the prevalence of metabolic syndrome in various countries and populations and to discuss the most frequently used diagnostic criteria, including racially and ethnically differentiated ones.Materials and method. A literary search was carried out using scientific databases: eLIBRARY, PubMed.NCBI, CyberLeninka, the official website of IDF for the period from 1999 to 2020.Results. It was found that despite different diagnostic criteria used for MS, its prevalence in many countries is comparable (10–30 %) but differs in different populations. Thus, MS occurs more often in Caucasians than among Asians, and its prevalence is significantly higher in the newcomer vs the indigenous population. Nevertheless, a comparative analysis of the frequency of MS is difficult due to the use of research results based on different approaches to its diagnosis in the literature presented in the literature. Although the analysis of literature data indicates the existence of specific features of the prevalence of MS in different populations, the differentiated approaches to detecting MS depending on the race of patients, which are necessary for many countries, have not yet been sufficiently developed.
Assessing risks of developing and persistence of infectious process in knee joint replacement
Authors: Grishchuk A. N. , Leonova S. N. , Kameka A. L.
Published: October 2021

Despite of intensive work on improving endoprosthetic replacement constructions, using minimally invasive techniques, developing methods of prevention for and treatment of periprosthetic joint infection, relapse of infection process can reach up to 52 % after treatment.The aim of the study: to show the importance of identifying the risks of development and recurrence of periprosthetic infection after implantation of a knee joint endoprosthesis. A clinical case of the development of a deep periprosthetic infection in a patient after primary knee replacement and successful treatment of the resulting complication was demonstrated. The analysis of this case of an infectious complication using the proposed prognosis for the development of periprosthetic infection showed that before surgical treatment of the patient, the risk of an infectious process was not assessed, and appropriate preventive and therapeutic measures were not carried out.Materials and methods. In the treatment of developed periprosthetic infection of the knee joint, the author’s algorithm for choosing surgical tactics was used, which allowed to determine the high risk of recurrence of periprosthetic infection, evaluate additional criteria and choose the optimal type of surgical intervention – two-stage revision endoprosthetic, which allowed to stop the infectious process.New was the use of the proposed prognosis for the development of periprosthetic infection and the algorithm for choosing surgical tactics for periprosthetic infection, which make it possible to determine the necessary preventive measures to reduce the risk of an infectious complication and to apply the optimal type of surgical intervention to relieve periprosthetic knee infection.
Functional state of the brain bioelectric activity in treatment of diaphyseal lesions of the radius using the transosseous osteosynthesis of the wire and rod arrangement
Authors: Kinash I. N. , Puseva M. E. , Butaev Ch. Z. , Verkhozina T. K. , Ippolitova E. G.
Published: October 2021

Radial fracture is the most common trauma to the musculoskeletal system and accounts for 50 % of traumatic injuries to the bones of the upper limb. Disability in patients with fractures of the forearm bones ranges from 6 to 8 months, so the choice of the most effective method of treatment is very relevant. Currently, an important point is the tendency of optimizing the transosseous method by eliminating the disadvantages and looking for new advantages of external fixation. Bone fracture and associated surgical intervention are always accompanied by varying degrees of changes in the links of the central nervous system, hemodynamics and metabolism. In order to study the bioelectrical activity of the brain in 47 patients with a fracture of the radial diaphysis treated in the Traumatology Department of the Irkutsk Scientific Centre of Surgery and Traumatology, in the pre- and postoperative period we compared EEG indicators of two variants of the layout of the external fixation apparatus (EF): wire and rod. Analysis of the rhythms of bioelectrical activity of the brain in both groups in the preoperative period revealed a normal zonal distribution with the dominance of the alpha rhythm on the EEG, which generally reflects a rather high degree of organization of neuroactivity and indicates the stability of cerebral homeostasis. At the same time, in the group of patients with a wire-mounted EF device in the postoperative period, EEG indices significantly differed from the values of the norm and ndicators in the group with a rod-shaped arrangement. A decrease in the amplitude of alpha and beta rhythms was noted, as well as a shift in the frequency of bioelectric activity towards slow waves, which is a sign characteristic of discirculatory encephalopathy. An EEG study using the method of transosseous osteosynthesis with EF devise of a rod assembly showed its greater efficiency compared to the use of an EF device of a wire assembly during treatment and rehabilitation. Thus, the study of the bioelectric activity of the brain is a reliable method for assessing its functional state after an injury, as well as the effectiveness of the treatment.
Analysis of the association of polymorphisms of genes markers functions of endothelium and vascular-plate hemostasis with development of diabetic foot syndrome
Authors: Troitskaya N. I. , Shapovalov K. G. , Mudrov V. A.
Published: October 2021

The aim. To study the prevalence of various combinations of polymorphic variants of genes markers of endothelial function and vascular-platelet hemostasis in the development of diabetic foot syndrome.Materials and methods. In 198 patients with uncomplicated diabetes mellitus and 199 patients with diabetic foot syndrome, the frequency of polymorphic variants of the NOS 786C>T, END1 Lys198Asn, ITGB3 1565T>C (Leu33Pro), F5 1691G>A, F2 20210G>A, MMP9 8202A>G, MTHFR 1298A>C, VEGFA-634C>G genes was studied. Using binary logistic regression analysis, the relationship of various combinations of polymorphisms of the studied genes with the development of diabetic foot was assessed.Results. In diabetic foot syndrome, the most significant contribution is made by the combination of polymorphic variants of the ITGB3 1565T>C (Leu33Pro) and MTHFR 1298A>C genes. With the development of this complication of diabetes mellitus, a combination of the 1565 TC polymorphism of gene ITGB3 and the 1298AA polymorphism of gene MTHFR is 2.1 times more common. The association of the 1565TT polymorphism of gene ITGB3 and the 1298AC polymorphism of gene MTHFR is 2 times more common in diabetes mellitus without complications.Conclusion. The combination of the 1565TС polymorphism of gene ITGB3 and the 1298АА polymorphism of gene MTHFR is associated with the risk of developing a diabetic foot and increases the risk of developing this complication by 2.4 times. The presence of a combination of the 1565TT polymorphisms of gene ITGB3 and the 1298AC polymorphism of gene MTHFR is more common in uncomplicated diabetes mellitus, which suggests its protective effect against the development of diabetic foot syndrome.
Features of physical activity and school anxiety in pupils of the secondary general education school and the cadet corps
Authors: Valina S. L. , Shtina I. E. , Ustinova O. Yu. , Eisfeld D. A.
Published: October 2021

Relevance. The relevance of the study is due to the high significance of school anxiety in the formation of psychosomatic diseases and nervous disorders. Identification of risk factors for increased anxiety, one of which is low physical activity, is important for the timely organizing of preventive measures.The aim: to assess the characteristics of physical activity and school anxiety among schoolboys of secondary school and the cadet corps.Materials and methods. The observation group consisted of 47 schoolboys studying in a secondary general school at the age of 13–16; the comparison group consisted of 140 schoolboys of the cadet corps. The comparative assessment of physical activity bases on the analysis of the physical education implementation in educational organizations and the results of a survey according to the author’s questionnaire. A comparison was made of the parameters of bioimpedance analysis (BIA) of body composition, the content of cortisol and serotonin in the blood serum, and indicators of the Phillips school anxiety test.The results. Physical activity in the school system was limited to 3 hours per week, and in the additional education system there are only 14.9 % of schoolboys who devote 6–8 hours a week to sports, which is 3 times less than in the comparison group (46.4 %). Lower values of indicators of physical activity and body composition were found in secondary school boys relative to those in cadet corps (p = 0.015–0.038). The level of cortisol in the blood serum was 1.4 times higher, and the serotonin was 1.2 times less in schoolboys of the schools comparatively to cadets (p = 0.001–0.037). In secondary school schoolboys, relative to cadets, significantly 1.9–3.9 times more often increased values were recorded for the factor general anxiety at school, frustration of the need to achieve success, fear of self-expression, fear of the situation of testing knowledge, fear of not meeting the expectations of others, problems and fears in relations with teachers and general anxiety oppositely directed correlations of weak and moderate strength were established between the frequency and duration of physical education, BIA parameters, cortisol in the blood serum and factors of school anxiety.Conclusion. The values of the factors of school anxiety schoolboys of secondary general school are higher than in boys of the cadet corps and possibly they are associated with irregularity, relatively low duration of physical activity and the degree of development of metabolically active tissues.
Short-term results of treatment of staphylococcal periprosthetic hip joint infection with combined antibiotics and bacteriophages treatment
Authors: Fedorov E. A. , Kretien S. O. , Samokhin A. G. , Tikunova N. V. , Korytkin A. A. , Pavlov V. V.
Published: October 2021

Infectious complications after primary implantation of the hip joint are 0.5–3 %, and in the case of re-endoprosthetics, the risk of periprosthetic infection can reach 30 %. Also, we should not forget about the high percentage (16–20 %) of recurrence of periprosthetic infection of the hip joint, which leads to an unsatisfactory result of treatment up to amputation of a limb or even death of the patient. The reasons for the recurrence of the infectious process can be antibiotic resistance and antibiotic tolerance of microorganisms, as well as the ability of microorganisms to form biofilms on implants. In this regard, there is a constant need to search for alternative means of antimicrobial therapy, as well as to select the optimal ways of their delivery and deposition, which is of practical importance when performing surgical interventions in traumatology and orthopedics to protect the implantable structure from possible infection of the surgical site. One of the methods currently available to combat bacterial infections acquired antibiotic resistance and antibiotic tolerance is the use of natural viruses that infect bacterial bacteriophages. The above suggests a more effective suppression of periprosthetic infection, including persisters that deviate from antibiotics. It is, as a rule, associated with biofilms if used in conjunction with antibiotics and phages, when the use of bacteriophages predetermines the effectiveness of treatment. With the use of sensitive bacteriophages in the treatment of periprosthetic infections, a significant (p = 0.030) reduction in the rate of recurrence of infection (from 31 to 4.5 %) was observed. The use of lytic bacteriophages in traumatology and orthopedics is of great interest for phagotherapy of infections caused by antibiotic-resistant and biofilm-forming strains of bacteria. A clinical study using a single-stage surgical revision with simultaneous application of antibiotics and phages in the treatment of deep periprosthesis infection of the hip joint endoprosthesis, followed by 12 months follow-up for periprosthetic infection recurrence, demonstrated the effectiveness of the use of combined antibiotic and bacteriophages treatment.
Coronavirus disease 2019 (COVID-19): NETosis-associated mechanisms of progression and prospects for therapy regulating the formation of neutrophil extracellular traps (NETs)
Authors: Aitbaev K. A. , Murkamilov I. T. , Fomin V. V. , Kudaibergenova I. O. , Yusupov F. A.
Published: October 2021

Infectious disease COVID-19 caused by the SARS-CoV-2 coronavirus is characterized by high contagiousness, complexity of pathogenesis and unpredictability of the clinical course. In severe cases, which are especially susceptible to men, the elderly and people with underlying medical conditions such as obesity, diabetes, hypertension, cardiovascular and chronic respiratory diseases, the infection leads to respiratory failure and death due to the development of an extensive inflammatory reaction. As a result of many studies, it has been established that one of the leading causes of the severe course and death of patients with COVID-19 is the development of coagulopathy, that is, increased thrombus formation in small vessels due to excessive activity of neutrophils, which form the so-called neutrophil extracellular traps (NETs). Although NETs play a useful role in protecting their host from pathogens, their overgrowth can trigger a cascade of adverse reactions including: the production of antibodies against the host’s DNA (autoimmunization); damage to surrounding tissue; or the occurrence of thromboembolic complications. Therefore, extracellular neutrophil traps and their markers have been identified as targets for new therapeutic strategies aimed at reducing the severity of COVID-19 disease and/or mortality. This article describes the structure of NETs, as well as analyzes the molecular mechanisms that contribute to their overgeneration. In addition, the prospects for COVID-19 therapy aimed at regulating the formation of extracellular traps by creating drugs both limiting the production of NET structures and dissolving their excess amounts in the body of patients are discussed.
Overview of potential drugs for the treatment of new coronavirus Infection (COVID-19)
Authors: Shirobokov Ya. E. , Gladunova E. P. , Borodulina E. A. , Sukhanova A. E.
Published: October 2021

The new coronavirus infection (SARS-CoV-2), better known as COVID-19, quickly evolved into a worldwide pandemic with a significant public health burden. Currently, there are no approved drugs or preventive therapeutic strategies to combat infection. Decisions about prescribing many medications are made based on the results obtained in in vitro studies, or expert opinions. Most of the drugs currently used to treat COVID-19 are approved antivirals or antibodies against other diseases. However, there are hundreds of clinical studies underway around the world to discover effective treatments for COVID-19. This article summarizes the results of clinical studies of potential therapeutic drugs used as COVID-19 therapy. Based on this review, it can be concluded that there is still no high-quality evidence to support any of the drugs described below. Until the unambiguous results of randomized controlled trials are available, the use of any of the following drugs is not clinically proven as an effective treatment for COVID-19.
Itineraries of an Anthropologist
Studies in Honour of Massimo Raveri
Authors: Bulian Giovanni , Rivadossi Silvia
Published: October 2021

This volume is a Festschrift in honour of Massimo Raveri, Honorary Professor of Japanese Religions at the Department of Asian and North-African Studies at Ca’ Foscari University of Venice. This wide-ranging collection features essays that pay homage to his extensive academic interests and his interdisciplinary approach to the study of classical and contemporary Japanese religions. It is a tribute by friends and colleagues wishing to express their esteem and affection towards a scholar who, over the course of his long career, has shared many research experiences with them, in a spirit of unfailing support and collaboration.
Massimo Raveri, the Oxford School of Social Anthropology and Researching and Teaching on Japanese Society
Authors: Goodman Roger , Hendry Joy
Published: October 2021

This paper explores the context in which Massimo Raveri has produced his corpus of work on Japan and explains how and why he has so successfully been able to cover such a wide range of topics – stretching from the pre-modern to the contemporary. It situates his work in the context of debates between those in the worlds of Japanology and Japanese Studies and considers how he and his work have acted as a bridge between the two. It also examines the influence on his work of the debates taking place in the Oxford School of Anthropology at the time that he studied in Oxford in the late 1970s and how his distinctive approach has influenced the social anthropology of Japan.