bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluation of lung adverse events with nivolumab using the spontaneous reporting system in Japan: a pharmacovigilance study
Authors: Kanbayashi Yuko , Shimizu Tadashi , Kojima Asuka , Anzai Miku , Kawai Rika , Uchida Mayako
Published: January 2023

Purpose: Nivolumab has been widely used in patients since its launch, but detailed information on lung-specific adverse events (AEs) from post-marketing monitoring has not been reported. We therefore conducted this study to examine times to onset, incidence rates, and outcomes of nivolumab-induced lung AEs in patients with cancer, using the Japanese Adverse Drug Event Report database.
Methods: We analysed data for the period between April 2004 and March 2021. Data on lung AEs were extracted, and relative risks of AEs were estimated using the reporting odds ratio.
Results: We analysed 5,273,115 reports and identified 18,721 reports of AEs caused by nivolumab. Of these, 3,084 lung AEses were reportedly associated with nivolumab. Signals were detected for nine lung AEs (expressed using terminology preferred by the Medical Dictionary for Regulatory Activities): interstitial lung disease; pneumonitis; lung disorder; organising pneumonia; pleural effusion; pneumonia aspiration; pneumonia bacterial; radiation pneumonitis; and infectious pleural effusion. Among these, interstitial lung disease was the most frequently reported (68.7%) and included some fatal cases. A histogram of median times to onset showed AEs occurring from 34 to 79 days after the first dose, but some cases occurred even more than one year after starting administration.
Conclusion: We focused on lung AEs caused by nivolumab as post-marketing AEs. Some cases could potentially involve serious outcomes, particularly in interstitial lung disease. Patients should be monitored for signs of the development of these AEs not only at the start of administration, but also over an extended period after starting nivolumab administration.
ELFN1-AS1 Promotes GDF15-Mediated Immune Escape of Colorectal Cancer from NK cells by Facilitating GCN5 and SND1 Association
Authors: Han Bin , He Jinsong , Chen Qing , Yuan Min , Zeng Xi , Li Yuanting , Zeng Yan , He Meibo , Zhou Qilin , Feng Dan , Ma Daiyuan
Published: January 2023

The ability of colorectal cancer (CRC) cells to escape from natural killer (NK) cell immune surveillance leads to anti-tumor treatment failure. The long non-coding RNA (lncRNA) ELFN1-AS1 is aberrantly expressed in multiple tumors suggesting a role as an oncogene in cancer development. However, whether ELFN1-AS1 regulates immune surveillance in CRC is unclear. Here, we determined that ELFN1-AS1 enhanced the ability of CRC cells to escape from NK cell surveillance in vitro and in vivo. In addition, we confirmed that ELFN1-AS1 in CRC cells attenuated the activity of NK cell by down-regulating NKG2D and GZMB via the GDF15/JNK pathway. Furthermore, mechanistic investigations demonstrated that ELFN1-AS1 enhanced the interaction between the GCN5 and SND1 protein and this influenced H3k9ac enrichment at the GDF15 promotor to stimulate GDF15 production in CRC cells. Taken together, our findings indicate that ELFN1-AS1 in CRC cells suppresses NK cell cytotoxicity and ELFN1-AS1 is a potential therapeutic target for CRC.
Spatial Variation in groundwater quality and Health Risk Assessment for Fluoride and Nitrate in Chhotanagpur Plateau, India
Authors: Sinha Heena , Rai Suresh Chand , Kumar Sudhir
Published: January 2023

The evaluation of groundwater quality is extremely important to assess the risk to human health. This study deals with the spatial variation in physico-chemical parameters of groundwater for drinking purposes and human health risk assessment concerning fluoride and nitrate. GIS techniques have been used to determine and delimit zones of pollution. Samples were collected in the post-monsoon season (November 2020) and analyzed for physico-chemical parameters such as pH, TDS, conductivity, cations, and anions. For drinking water quality assessment, analyzed parameters were compared with WHO standards, and Water Quality Index (WQI) was used. Results reveal that the majority of the samples come within the desired limit suggested by WHO. However, in a few samples, EC, TDS, TH, chloride, sulphate, and calcium are higher than the desirable limit, whereas fluoride and nitrate are beyond the maximum permissible limit in some of the samples. To assess health risk, the Hazard quotient (HQ) and total hazard index (THI) were computed. The results indicate that the total non-carcinogenic risk for children, male and female ranges from 0.01 to 7.46 for males, 0.009 to 7.055, and 0.01 to 7.34 for children respectively. Furthermore, 84%, 78%, and 82% of the samples are greater than the recommended limit of THI > 1 for males, females, and children respectively, suggesting detrimental impacts on the health of the residents. Knowledge of spatial variation and anomalous concentration is vital for groundwater management as well as health risk assessment. The findings of this study will be helpful to government officials, policy planners, NGOs, and local communities.
Clinical Outcomes in Ventilator-Associated Pneumonia Patients with and without Chronic Obstructive Pulmonary Disease: A Retrospective Observational Study
Authors: Lu Caiden Taowei , Hung Ming-Szu , Lin Yi-Tsung , Fang Tien-Pei
Published: January 2023

Background
Chronic obstructive pulmonary disease (COPD) is the third leading cause of death worldwide. Critically ill patients with COPD exacerbations may require invasive mechanical ventilation (IMV). Ventilator-associated pneumonia (VAP) commonly occurs in the intensive care unit (ICU) and is usually associated with high mortality. Current studies on the relationship between COPD and VAP are limited. This work compares the etiology and clinical outcomes of VAP between patients with and without COPD in Taiwan.
Methods
This retrospective observational study was conducted at the Chiayi Chang Gung Memorial Hospital. Patients with VAP were enrolled between January 2015 and December 2019. The COPD diagnosis was based on post-bronchodilator pulmonary function tests. We compared the bacterial etiology, ICU and hospital stay length, IMV duration, and mortality.
Results
A total of 175 patients with VAP were enrolled, 44% of whom presented pre-existing COPD. The disease severity on the day of admission was similar in both groups. Microorganisms were identified in 83 (47%) patients, with Pseudomonas aeruginosa, Acinetobacter spp., and Stenotrophomonas maltophilia being the most common pathogens. Acinetobacter spp. were more frequently isolated from patients with COPD than from those without. The proportion of multi-drug resistant isolates showed no significant differences between groups. Most patients underwent antibiotic treatment before VAP onset. The length of ICU and hospital stays and IMV duration after VAP onset were similar between groups, as well as ICU mortality and 30-, 60-, and 90-day mortalities.
Conclusions
Our study revealed that COPD was not associated with worse clinical outcomes in patients with VAP. Patients with VAP and concomitant COPD were more susceptible to Acinetobacter spp. than those without COPD. Our results may provide a rationale for empirical antibiotic coverage in this group.
Isolation and identification of Lacticaseibacillus rhamnosus YT and the antibacterial characteristics of its cell free supernatant and cells
Authors: Guan Chengran , Su Jianbo , Li Feng , Zhang Wenjuan , Chen Dawei , Chen Xia , Huang Yujun , Zhang Chenchen , Gu Ruixia
Published: January 2023

Lactic acid bacteria (LAB) which produce diverse imperative antimicrobial metabolites have an immense number of applications in food industry. Here, human-derived strain YT was isolated due to its cell free supernatant (CFS-YT) and cells (Cs-YT) respectively performed obvious inhibitory ring to Gram positive and negative spoilage bacteria. Strain YT was identified as Lacticaseibacillus rhamnosus YT by 16s rDNA sequence and morphology. The antibacterial activity of CFS-YT was demonstrated to be growth-dependent, pH sensitive, broad thermostable and proteases insensitive. Cs-YT displayed a broad antibacterial spectrum with the action mode of bacteriostatic. The antibacterial activity of Cs-YT was due to substances located at the cell surface which was sensitive to heat, stable at broad pH gradients and sensitive to specific proteases. These data suggested that L. rhamnosus YT could be used as alternative antimicrobial agents against foodborne spoilage bacteria in food industry.
A Case Study on the Spread of Fake News by Social Media in the COVID-19 Era in Bangladesh
Authors: Hossain Imran , Haque AKM Mahmudul
Published: January 2023

Fake news has negative impacts on society. It can sometimes cause the death of a person. In Joypurhat, Bangladesh, a garment worker has committed suicide because of fake news. At midnight, a passenger on a bus in Bangladesh's Naogaon district believed Corona had affected his mother. However, after testing, his Corona report came back negative. So, this incident has also happened based on fake news. With the internet, social media have become the most acclaimed tool for freedom of speech, democracy, truth, and as a source of infotainment. In this study, the researchers have attempted to find out whether social media is informing or misinforming the public with regard to the COVID-19 pandemic, adopting the qualitative method of study. The findings of this study will aid in determining whether social media is disseminating accurate or incorrect information to the public about the COVID-19 outbreak. The findings show that social media generates approximately 100 COVID-19-related fake news stories over the course of 150 days, from March 1 to July 30, 2020. In this research, the results also show that 64.6% of respondents get COVID-19 related information through social media. In this aspect, Facebook plays an important role. About 53.0% of social media users acclaimed that they get COVID-19 related fake information through Facebook. Facebook spreads 63.0% of fake news, and it is the quickest way to spread any fake news in a short period of time. Most of the fake news is a combination of text and video (49.0%). So, social media is a large platform for getting COVID-19 related information. Fake news and rumors are new words related to COVID-19. This study reveals that 87.3% of respondents are familiar with these words, whereas 12.7% were not familiar with them before the COVID-19 era. About 47.6% of respondents never try to verify any rumors or information related to COVID-19. However, there is less research analyzing the circulation of false and evidence-based information during health emergencies. Thus, the present study aims at shedding new light on the type of fake news that circulated on social media around the COVID-19 outbreak in order to analyze how false information was shared.
Effect of (4R, 5S) 4-hydroxy-7-angeloyloxycarvatoneacetone from Blumea axillaris (Lam.) DC. plant against An. stephensi and Cx. quinquefasciatus vector mosquitoes (Diptera: Culicidae) and expression of different functional genes
Authors: Hillary V. Edwin , Sivanandhan S. , Ceasar S. Antony , Ayyavoo K. , Tamilselvan C. , Kumar M. Ravi , shirotta Osamu , Balakrishna K.
Published: January 2023

The present study was conducted to evaluate the mosquitocidal efficiency using a compound isolated from Blumea axillaris (Lam.) DC. against Culex quinquefasciatus and Anopheles stephensi. The compound isolated from leaves of B. axillaris is (4R, 5S) 4-hydroxy-7-angeloyloxycarvatoneacetone. This isolated compound was exposed to eggs and larvae of An. stephensi and Cx. quinquefasciatus and with different concentrations of 0.5, 1.0, 1.5, and 2.0 ppm. Primarily, the hexane extract of an isolated compound exhibited promising larvicidal activities of LC50 and LC90 values of 155.811 and 566.763 ppm against An. stephensi and 77.215 and 99.653 against Cx. quinquefasciatus at 24 hours. Secondly, the compound isolated from B. axillaris at 2-ppm concentration exhibited LC50 and LC90 values of 0.85 and 3.59 and 1.19 and 3.678 ppm against Cx. quinquefasciatus and An. stephensi larvae, respectively. Furthermore, histopathological studies revealed serious damage to the larval midgut cells in both Cx. quinquefasciatus and An. stephensi (treated with compound). Additionally, it showed 81.0% and 84.2% ovicidal activity against both Cx. quinquefasciatus and An. stephensi eggs at 120 h post-treatment. In addition, we also analyzed the influence of isolated compound on the expression of different functional genes of An. stephensi and Cx. quinquefasciatus namely (1) White (Wh) gene, which is responsible for eye pigmentation; (2) the Glutathione transferase (GST) gene that helps for survival when exposed to any insecticides or pesticides; (3) Cytochrome P450 monooxygenase (CYP450) gene that enhances resistance in mosquitoes to digest pesticides and (4) Esterase (Est) gene, which helps in resistance to the variety of insecticides. These overall studies and results clearly suggest that compounds from B. axillaris could act as good mosquitocidal agents against both Cx. quinquefasciatus and An. stephensi and the compound were also first time reported as mosquitocidal activity.
Geographical Disparities of uncertainty stress and life stress among university students in China
Authors: Yang Tingzhong , Sihui Peng , Wang Huihui , Oliffe John L.
Published: January 2023

Background
Ecological models have emphasized that mental stress both is an individual phenomenon and an environmental outcome. However, many mental stress studies focused primarily on individual variables. Few studies have examined the geographical disparities in mental stress, with no comparable studies implemented on this issue with regard to different type of mental stress. This study investigates geographical variations in overall stress, uncertainty stress and life stress among university students in China.
Methods
Respondents comprised 11,954 students from 50 universities and 31 provinces in Mainland China. Respondents completed the extended version of the Global Health Professional Student Survey (GHPSS) on Tobacco Control in China. The survey included additional health, mental stress, and behavioral items along with regional variables which were retrieved from the National Bureau of Statistics database. Both unadjusted and adjusted methods were used in the logistic regression analysis.
Results
Uncertainty stress and life stress prevalence were 19.6% (95% CI: 15.9%, 23.3%) and 8.6% (95% CI: 7.2%, 10.7%) respectively, while overall stress prevalence was 37.2%, 95% CI: 24.7%, 49.7%). All stresses varied widely across the 31 provinces. Random parameters of 0.3971 for life stress, 0.2593 for uncertainty stress, and 0.1449 for overall stress were statistically significantly at the 0.01 level, in terms of their geographical distribution, high life stress was concentrated in central provinces, high uncertainty stress mainly in both central and western provinces, while provinces displaying higher overall stress tended to display a north-south distribution. Multilevel logistic regression showed province level per capital disposable income of households partly contributed to uncertainty stress (OR: 0.52) and life stress (OR: 0.59).
Conclusions
This study maps the geographical distribution of uncertainty stress, life stress, and overall stress in China. These findings underscore the importance of environmental factors affecting stress levels among university students.
An in-Silico approach to evaluate the binding efficacy and stability profile of MWCNT entangled rutin for breast cancer treatment
Authors: Bhusan Kirthi , Ammunje Damodar Nayak , Kunjiappan Selvaraj , Jyaraman Anbu , Devi Manisha , Pavadai Parasuraman
Published: January 2023

Cancer is one of the most devastating diseases and ranks second in a total number of deaths caused globally. In recent years there is a steady increase in breast cancer (BC) incidence due to several etiological factors. Due to indiscriminate drug delivery and the lack of target specificity, current cancer therapies can cause life-threatening side effects. The present research emphasises targeting the rutin-loaded onto carbon nanotubes (CNTs) for breast cancer treatment. Intermolecular interaction studies between rutin (PubChem CID 5280805) and the target protein folate receptor (PDB ID 4LRH) via Autodock Vina programme and PyRx tool was carried out, and the docking score was found to be -8.7 Kcal mol− 1. In comparison, that of the standard chemotherapeutic drug 5-Fluorouracil was − 5.9 Kcal mol− 1. Molecular dynamic studies were performed via Desmond for 100ns. The root-mean-square deviation (RMSD) value of the ligand remained stable, root-mean-square fluctuation (RMSF) values have been observed to be stable throughout the simulation time. Based on these promising results, rutin-loaded CNTs can be further evaluated for their efficacy against breast cancer preclinically.
Active poly (lactic acid) films with rice straw aqueous extracts for meat preservation purposes
Authors: Freitas Pedro A. V. , González-Martínez Consuelo , Chiralt Amparo
Published: January 2023

Aqueous extracts from rice straw, using ultrasound-assisted reflux heating extraction (USHT) and Subcritical Water Extraction (SWE), under two process conditions (160°C, 7 bars; and 180°C, 11 bars), were obtained and characterised as to their phenolic content and antioxidant and antimicrobial capacities. These extracts were incorporated (6% wt.) into PLA films by melt blending and compression moulding that were characterised as to their structural and functional properties and their capacity to preserve fresh pork meat, as vacuum thermo-sealed bags, throughout 16 days of cold storage. The extracts slightly reduced the extensibility, resistance to break and water barrier capacity of the PLA films but enhanced their oxygen barrier capacity and the UV light-blocking effect. The films with RS extracts were effective at preserving meat quality parameters, inhibiting microbial growth, meat oxidation, discolouration, and weight loss, thus extending the meat shelf life. The SWE extract obtained at 180°C was the most effective at obtaining active films for meat preservation, exhibiting the greatest antioxidant and antibacterial activity. Therefore, the green SWE technique is useful for obtaining active extracts from RS, allowing for its valorisation in the development of biodegradable active materials useful to extend the food shelf life.
High optical properties of solar cells devices to produce clean energy
Authors: Afroozeh Abdolkarim
Published: January 2023

The important of sustainable energy supply in today’s world has led to widely efforts by researchers to find an alternative source. In this paper we present a renewable resource called solar cell. Also, traditional solar cells is analysed which help us design new devices with high conversion energy. In other world to solve the problem and limitations of old solar cells devices like low efficiency, expensive operating process and not economically to use in large scale, perovskite solar cells (PVCs) proposed. Perovskite solar cells have the highest capability compared to other solar cells like Si-based photovoltaic solar cells and CFTs solar cells, with high efficiency and cost effectiveness. It is noteworthy that the discovery of new materials with unique properties such as graphene help researchers to improve solar cells efficiency. Beside this graphene-based perovskite devices are enabled rapid progress with high efficiency. To note developed solar cells technology pave the way for easy processing, mass production and commercialization.
Cardenolide glycosides from the aerial parts of Pergularia tomentosa.L and their biological activities
Authors: BABAAMER zohra , Al-abdallah Nesren Ghazi , kouadri fayza , zarga musa Abu
Published: January 2023

The authors have requested that this preprint be removed from Research Square.
The Association Between Birth Weight and the Risk of Neuroblastoma: A Meta- Analysis of Observational Studies Involving 4,361,141 Participants
Authors: Arayici Mehmet Emin , Cecen Refik Emre , Basbinar Yasemin , Ellidokuz Hulya , Olgun Hatice Nur
Published: January 2023

Purpose
One of the most common extracranial childhood solid tumors is neuroblastoma. In this study, it was aimed to perform a systematic review and meta-analysis to evaluate the risk of neuroblastoma in both high and low birth weight.
Methods
The PRISMA and MOOSE guidelines were followed during the design, analysis, and reporting of this study. A comprehensive literature search was performed for the published papers in Embase, PubMed/Medline, Scopus, and Web of Science databases. The odds ratio (OR) of neuroblastoma in high and low birth weight groups, with 95% confidence intervals (CIs), were calculated using the random-effects and fixed-effects model.
Results
A total of 16 papers and 4,361,141 participants were included in this study. In this meta-analysis, it was observed a U-shaped relationship between birth weight and neuroblastoma. Individuals with both high and low birth weights may face an increased risk of developing neuroblastoma later in life (OR = 1.17, 95% CI: 1.06–1.29, p = 0.002; OR = 1.19; 95% CI: 1.03–1.37, p = 0.017, respectively).
Conclusion
As a result, both high and low birth weight in individuals may be among the important risk factors for neuroblastoma development.
A Climate Justice Based Model for Carbon Budget Allocation
Authors: Fabiyi MALCOLM
Published: January 2023

Current Integrated Assessment Models (IAMs) and general carbon budget models do not sufficiently account for climate justice in their allocations of future emissions. To address these limitations, several modeling frameworks such as equal per capita (EPC) and per capita convergence (PCC) that aim to incorporate fairness and justice more comprehensively into emissions attribution and carbon budget allocation have emerged. We propose a novel integrated attribution – allocation (IAA) model construct that robustly incorporates three equity principles of responsibility, capability, and equality into the estimation of carbon budget emissions allocations. Results demonstrate that simple reductions of responsibility for climate action to categories such as global south vs global north and developed vs developing cannot be established a priori as methodologies for fairly and justly assigning emissions rights and mitigation obligations.
Impact on performance, combustion and exhaust emission characteristics using mahua oil and diesel blends
Authors: Pavuluri Subramanyam , Reddy B.Sidda , Prasad B.Durga
Published: January 2023

Today’s energy scenario has propagated and enhanced the research in the non-conventional, renewable and environmentally friendly fuels. The increasing cost of conventional fuels has motivated researchers to look at renewable alternatives for use in internal combustion engines. When compared to other seed fuels like ethanol and essential oils, mahua oil has comparable low viscosity, boiling temperature, and flash point. The present paper discuss on the experimental investigations carried out using the blends of Mahua oil and diesel. The blends are prepared on a volume basis and designated as MO10, MO 20, MO 30 and MO 40. It is observed that BTE increases for MO10 and MO20 blends by 2.7 and 5.8% respectively. Whereas there is a decrease in CO, HC and smoke emission compared to diesel. The NOx Emission levels for all Mahua oil blends increased due to rise In-cylinder pressure.
Site selection of hydropower station based on three-way MADM considering intuitionistic fuzzy rough numbers
Authors: Liu Fang , Liu Yi , Wu Ju , Xu Lei , Zhou Zhongli
Published: January 2023

With the rapid development of modern society, the construction of hydropower stations has produced a series of ecological and environmental problems, which are becoming increasingly serious. The siting of hydropower stations is a multi-attribute decision-making problem. Considering the successful application of three-way decision (TWD) in multi attribute decision-making (MADM), combined with the advantages of intuitionistic fuzzy rough numbers (IFRNs) to deal with uncertainty problems, a new method of three-way MADM is proposed and applied this model to the siting of hydropower stations. The main contributions of this work are as follows: (1) According to characteristics of IFRNs, a method of calculating relative loss function based on IFRNs is proposed; (2) Combining advantages of objective weight and subjective weight calculation method, a new method for calculating combination attribute weight is put forward; (3) By extending the grey relational analysis method, a conditional probability calculation method based on IFRNs is proposed. (4) a three-way MADM method to classify and rank alternatives is proposed, and the corresponding algorithm description is given. Then, the calculation steps and ranking results of the method are illustrated by an example of hydropower station location. At last, we verified the feasibility and effectiveness of the method through comparative analysis, and analyzed the influence of each parameter on the classification and ranking results.
Aspects and Background of Records Describing Goryeo as an Island in Medieval Islamic Literature and European Literature
Authors: Lim Hyung-Soo
Published: January 2023

Some types of literature created in the Islamic world and Europe during the medieval period describe Goryeo’s topography as an island or a group of islands instead of a peninsula. Such records have been mentioned several times in diverse fields, including history, geography, and cartography. This study reviewed medieval Islamic literature and European literature published in the Islamic world and Europe, respectively, over hundreds of years. It organized records describing Goryeo, as well as Silla and Joseon—kingdoms established before and after Goryeo, respectively—as an island or group of islands and analyzed the background that caused medieval Arab and European people to regard these places as such. The analytical results indicate that the background for medieval Arab and European people’s perception of the Korean Peninsula as an island or group of islands differed by region and period. This study’s results suggest that these inaccurate records on Silla, Goryeo, and Joseon were created because writers who never traveled to the Korean Peninsula referred to false knowledge passed down from their ancestors and unreliable information directly or indirectly obtained from adjacent countries. They mixed fictitious and factual stories when writing their books.
Managing the risks of the Coronavirus Pandemic: the case of the Mediterranean island of Menorca
Authors: Pastrana-Huguet Josep , Casado-Claro Maria-Francisca
Published: January 2023

The COVID-19 crisis could act as a catalyst for a series of social, economic, and political changes since it has sensitized governments and institutions on the need for a structural paradigm shift in their growth models from a triple economic, environmental and social perspective. This article offers a case study of the Spanish island of Menorca and its incidence rates in comparison with other territories of the European Union and Spain. Furthermore, we offer a brief description of the current context of the island and its function during the 19th century as a point of control and containment of infectious diseases in the Lazaretto of Maó. This study intends to interpret how the COVID-19 management has been carried out considering the actions made at the State, regional (autonomous community), insular and local levels. The paper is focused principally on the preventive actions at the insular level to know if some of these actions made during the crisis Covid and insular particularities before the start of the pandemic are conditions for the control of the COVID-19 and its incidence rates on the island.
Gender roles in the Anchovies Food Supply Chain – Bagang System in Mempakad Laut, North Borneo, Malaysia
Authors: Foo Jurry , Hamdan Diana Demiyah Mohd , Amirul Sharifah Rahama , Sapari Siti Muslihah , Janoni Nur Hazirah , Jotin Emily
Published: January 2023

This article examines the roles of gender in the Bagang system, an organisation of the anchovy supply chain in Mempakad Laut, Sabah, Malaysia bordering the Marine Protected Area named Tun Mustapha Marine Park. Gender study on marine ecosystem management is important to understand the involvement of men and women specifically on how they are complementing each other in ensuring effective resource management. This exploratory study was obtained via qualitative approach as the data collections method including Focus Group Discussion (FGD), interviews as well as field observation. A total of 30 informants participated in this study which were selected through purposive sampling and snowball sampling method. Findings reveal that men and women are equally important in the Bagang system. Men work on marine affairs and material development, while women work on product processing and marketing. The contribution of women in the sustainability of the Bagang system was significantly visible and was treated equally in most aspects notably in financial management and in the decision-makings from the initial to the end of the anchovy supply chain. These findings are very important as guidelines to plan a better sustainable marine management for the future and a fine example of how sustainable fisheries can be achieved in supporting the United Nations Sustainable Development Goals No. 5 which is gender equality.
Topeng Kona: A Sacred Dance in the Ritual Bersih Desa at Blimbing Village, Bondowoso Regency, East Java, Indonesia
Authors: Izzah Latifatul , Rochwulaningsih Yety , Sulistiyono Singgih Tri
Published: January 2023

This study aimed to describe the procession of the ritual ‘Bersih Desa’ and analyze the existence of the sacred dance ‘Topeng Kona’ as a tool for validating the ritual ‘Bersih Desa’ in Blimbing Village, Bondowoso Regency, East Java, Indonesia. The intelligence and local wisdom possessed by the ancestors of Blimbing Village, was able to give birth to masterpieces of high noble value in the ritual ‘Bersih Desa’, such as ‘Topeng Kona’ dance, ‘Singo Ulung’ dance, Tandhe’ Bini’ and ‘Ojhung’ dance. The masterpiece was the result of the marriage of two cultures, namely Javanese culture (represented by the figure of Juk Seng or Juk Singo Ulung) and Madurese culture (represented by the figure of Juk Jasiman). The result of the marriage produced a migrant culture with a high value that differed from the culture of the migrant’s home region. The sacred dance ‘Topeng Kona’ was used as a medium to validate the ritual ‘Bersih Desa’ as a form of appreciation for Jasiman figures who came from Madura and became the member of the residents of Blimbing Village.
Gender inequalities in a tourist region: the case of the Canary Island companies in a pre-pandemic scenario
Authors: Flores-Muñoz Francisco , Báez-García Alberto Javier , Gutierrez-Barroso Josué
Published: January 2023

The Canary Islands conform the most populated ultra-peripheral region of the European Union with almost two million inhabitants, receiving more than 13 million tourists in 2019, in a pre-pandemic scenario. Therefore, the islands represent a very particular setting to explore the impact of the global pandemic in business in general, and also in gender diversity and the situation of women on corporate boards in particular. Firms from several industries were observed in detail, as retail, wholesale, construction, manufacturing, repair and sale of vehicles and accommodation. The study explores the setting just before the advent of the coronavirus to their lives in a region which is obviously highly fragile to these events. The study reveals huge gaps in gender equality, with women less present and with less executive power than men, particularly in companies with better results and from certain industries, which confirms previous stereotypes. Further research will be required by means of longitudinal studies.
Time-reparametrization invariances, multithermalization and the Parisi scheme
Authors: Kurchan Jorge
Published: January 2023

The Parisi scheme for equilibrium and the corresponding slow dynamics
with multithermalization - same temperature common to all observables,
different temperatures only possible at widely separated timescales -
imply one another. Consistency requires that two systems brought into
infinitesimal coupling be able to rearrange their timescales in order
that all their temperatures match: this time reorganisation is only
possible because the systems have a set of time-reparametrization
invariances, that are thus seen to be an essential component of the
scenario.
Land use decision-making on residential plots in Fingo Village, Makhanda (Grahamstown), South Africa
Authors:   , Memela Sinehlanhla Truth
Published: January 2023

This study seeks to understand land use decision-making dynamics on large residential plots in Fingo Village, Makhanda (Grahamstown). Fingo Village was selected as a study area because it is one of the poorest urban settings in South Africa where urban poverty is observed alongside access to land. A dominant economic perspective not only suggests that land use decisions are motivated by economic motives, but also implies that access to land would enable people to generate income from its use to improve their livelihoods. This study argues against an uncritical embrace of this assumption. Lefebvre’s production of space thesis provides a holistic understanding of the factors involved in the making of land use decisions. The focus of this study is on the dialectic process in the spatial triad– spatial practice, representational space and representations of space. This involved the reading of government policies and legislation together with local lived experiences to gain an understanding of the particular spatial practices seen in Fingo Village. Snowball and convenience sampling were used to select 36 household plots in Fingo Village. Primary data was gathered by means of semi-structured interviews and participatory mapping while additional information was sourced from secondary sources and desktop analysis. The findings of the study show that there is no uniform pattern of land use and success. Different land use activities found on the selected residential plots, including the main house, backyard flat or flats, spaza shops, a funeral parlour, livestock keeping, cultural use (a kraal for ancestral worship) and food gardening. These activities are motivated by residents’ perceptions and attitudes towards their spaces, as well as the value and meaning they attach to the land which is not limited to economic factors, but is also influenced by socio-cultural, political and biophysical considerations. Although some spatial practices are prohibited by the government, they are important to the residents. Other participants fail to use the land as would be expected by a conventional economic perspective, due to spatial conflict relating to different interests as a result of collective land ownership and the failure of municipalities to enforce policies and regulations. The fact that numerous factors influence households’ land use decisions means that access to land does not always directly translate into economic benefits. It is all about what people think or do about their land, as well as what the state lays out in terms of policy and legislation, that will influence whether those people with large plots of land will ‘prosper’ or not.
A carne é fraca: humor como denúncia
Authors: Oliveira Cintia Rodrigues de , Alcadipani Rafael
Published: January 2023

Neste artigo, nós documentamos as manifestações de internautas nas redes sociais online quando veio a público uma operação deflagrada pela Polícia Federal no Brasil contra a corrupção corporativa, com grande repercussão nacional e internacional, a “carne fraca”. Nosso objetivo é compreender a utilização do humor nas manifestações contra as supostas ações criminosas de corporações, especialmente quando essas atingem os usuários das redes sociais online que, potencialmente, podem ser consumidores dessas empresas. A pesquisa é de natureza qualitativa, do tipo documental e utilizamos a análise temática com foco na intertextualidade e no humor presente em memes. Analisamos a apropriação nos memes difundidos nas redes sociais Facebook e WhatsApp, buscando reconhecer de que modo o humor foi utilizado pelos usuários. Nossa análise identificou que os memes representam uma estratégia de resistência discursiva contra os crimes corporativos, a qual se manifesta na forma do humor como denúncia:  denúncia das corporações, denúncia da nossa fragilidade perante as corporações e denúncia contra o marketing corporativo.
Aprender a reciclar: um olhar sobre as práticas de trabalho
Authors: Junges Vanessa De Campos , Campos Simone Alves Pacheco de , Becker Rúbia Goi
Published: January 2023

Este estudo tem como objetivo compreender como a prática do trabalho coletivo da reciclagem é apreendida, produzida e reproduzida, a partir de um estudo de caso em uma associação de reciclagem. A elaboração dos dados empíricos tomou por base o método de zoom in e zoom out, operacionalizado por meio de técnicas etnográficas. A análise foi desenvolvida por meio de análise textual e uso de templates. Os dados revelam que os praticantes ressignificam a prática do trabalho coletivo da reciclagem mediante negociação e reflexividade, suspendendo o fluxo da ação anterior e legitimando um novo repertório de construções normativas, reconhecidas conjuntamente. Concluiu-se que o modo de organização e aprendizagem dos recicladores propicia, ao longo do tempo, a construção e a reconstrução de práticas produzidas nas interações entre sujeitos, conhecimento e materialidade, fazendo com que a prática do trabalho coletivo da reciclagem mantenha-se em refinamento constante. Estes achados, especialmente no tocante ao trabalho coletivo, revelam nuances sobre o processo de organizing e learning, incentivando gestores a superar, por meio da aprendizagem pela prática, desafios advindos de projetos sociais.
SEPARATION PERFORMANCE OF PEG-LINKED CALIX[4]ARENE AS STATIONARY PHASE FOR CAPILLARY GAS CHROMATOGRAPHY
Authors: Zhang Wei , Cai Zhiqiang , Li Wei , Huang Qiuchen , Chen Ruonan , Li Yiwen , Jin Keyun , Zhao Yi , Sun Tao
Published: January 2023

This work presented a new PEG modified calix[4]arene stationary phase (C4A-PEG-2PTSC) for gas chromatographic (GC) separations. The statically coated C4A-PEG-2PTSC column exhibited moderate polarity and column efficiency of 2224 plates m-1 determined by 1-octanol at 120 oC. The results showed that the C4A-PEG-2PTSC column exhibited the good separation performance for various types of analytes containing halogenated benzenes, benzaldehydes, phenols, alcohols, anilines isomers and showed the different retention behavior with the comparative columns. Importantly, it showed the better separation capacity of toluidine and xylidine isomers than commercial HP-35 column. Moreover, it was applied in practical sample analysis to detect the content of isomer impurities. This work exhibited the good application potential of C4A-PEG-2PTSC stationary phase in GC analyses.
Diat and Peace Money in the Crime of Culpable Homicide
Authors: Hapsin Abu , Nurdin Nazar
Published: January 2023

Islamic Law and Indonesian Criminal Law place compensation as an essential part of criminal liability. The fundamental difference is that compensation is primary in Islamic law, while positive law is an alternative. This paper examines and compares the application of the theory of diat and compensation in the crime of culpable homicide. The writing is framed with a normative-empirical approach, with data sources from books and court decisions. The results of the study show three things: First, diat and peace are different conceptions. Diat refers to property given in exchange for a slain soul, while peace is given as a compensation fee and as an effort to forgive. Second, the amount of compensation in the diat is regulated in detail with a certain nominal. At the same time, positive law is an agreement considering the perpetrator's ability. Third, compensation in the diat is an inspiration for developing legal theories such as restitutive justice, which emphasizes the importance of forgiveness and reconciliation between two parties. Research suggestions so that the diat theory can be developed into modern law so that it can be an inspiration for lawmakers so that in its application, the diat theory can be a reason for the abolition of crimes, not limited to leniency.
Grants as a Model of Inheritance Prospective Distribution in the Coastal Santri Community
Authors: Muhtarom Ali , Nugroho Yuli Sutoto
Published: January 2023

The practice of Islamic inheritance law in Muslim communities in Indonesia experiences many obstacles. One of the reasons is that there is still a tradition of distribution of assets when parents are still alive and the prevailing kinship system. It was found in transferring property to the coastal santri community in Pekalongan City. This paper reveals the method of dividing the prospective inheritance of the coastal santri community and the mechanism for resolving disputes in the event of a dispute. This article uses a qualitative socio-legal studies approach and is descriptive and analytic. This article finds two things. First, the model for distributing the assets of the coastal santri community in Pekalongan City is carried out using grants orally and deliberation for consensus. Prospective inheritance is divided by the grant system equally, without distinguishing between men and women. The dispute resolution mechanism is carried out in negotiation and mediation.
An Assessment of Independent Sharī'a Panel (ISP) and Its Roles in Resolving Marital Conflicts in Osun State of Nigeria
Authors: Aremu Tijani Abdul-Lateef , Aladire Musa-Jeje Ibrahim , Sikiru Alimi Lawal
Published: January 2023

Every relationship, including marriage, is prone to conflict. There have been many solutions offered in dealing with this problem. The Independent Sharī’a Panel (ISP) in Osun State, Nigeria, is a panel that plays a role in resolving marital conflicts in Osun State. This article aims at describing the family conflict resolution program in Osun State. This article is a result of the study employing both quantitative and qualitative methods. The data gathered were from the field involving the interviews. This article reveals that marital conflict in Osun State is rampant and tends to increase yearly. This study also identified that the Independent Sharī’a Panel has served as a credible alternative mechanism, resulting in the resolution of many marital conflicts in this state. This research recommends that the Independent Sharīʿa Panel initiates a strong orientation program for young people on successful marriages, the consequences of marital discord, and how to resolve the issues.
Sirri Marriage Celebration and Its Impact on Social Change in Banjarese Community, South Kalimantan
Authors: Hafidzi Anwar , Bahran Bahran , Luthfi Fuad , Rusdiyah Rusdiyah , Ali Mohd. Hatta Mohamed , Esfahani Ali Banaeian
Published: January 2023

This study seeks to reveal that sirri marriages, which are usually secret, in the Banjar community are carried out openly and are carried out by walimah 'ursy (wedding ceremonies). In contrast to other studies, most of them only discuss the law of unregistered marriage and its legality in Indonesia. This study tends to pay more attention to aspects of habits and shifts in the meaning of the sirri marriage. The method used in this study is empirical with an ethnographic-phenomenological approach to the celebration of sirri marriages in the Banjar community, South Kalimantan. The results of this study prove that the legality of sirri marriages is illegal in Indonesia State because it is not recorded at the Office of Religious Affairs. However, aspects of the habit of unregistered marriages and holding wedding celebrations in the Banjar community,  make sirri marriages "as if" they have legal rights in society based on social norms.
Characteristics of the flow in channels with extended boundaries
Authors: Kamal M. , Fattouh E. , Mokhtar M. , Ead S.
Published: January 2023

In the flow in channels with extended boundaries, the channel sides are extended covering parts of the channel flow surface symmetrically or asymmetrically. The pressure on the top surface remains approximately atmospheric, while the distributions of both velocities and discharges in the flow cross-section are severely affected. In this study, cases with different asymmetric extension ratios and aspect ratios were experimentally examined. The effect of the roughness of both extensions and the flume bed was investigated. The velocity data were sampled using Acoustic Doppler Velocimeters. The resulting velocity iso-lines showed deformations due to asymmetricity and the maximum velocity distribution was shifted towards the sides of smaller extension ratios. Low-velocity zones were formed bounded by the extensions, the side boundaries, and the flume bed where the flow resembles that of a closed conduit with maximum velocity value near the middle, but with a major difference that the iso-lines are not closed due to the absence of the fourth boundary. In cases with a larger aspect ratio and roughness, high turbulence was noticed with severe cross-currents resulting in a low-flow velocity component. Results are demonstrated through figures and tables and the data were tested against well-known equations available in the literature.
Morphoanatomical Characterization and Chemical Composition of Essential oils of Lippia lupulina Cham. and Lippia pohliana Schauer (Verbenaceae)
Authors: Morais Sandra Ribeiro de , Oliveira Thiago Levi Silva , Abdalla Dayana Figueiredo , Thomaz Douglas Vieira , Tresvenzol Leonice Manrique Faustino , Conceição Edemilson Cardoso da , Rezende Maria Helena , Fiuza Tatiana de Sousa , Ferri Pedro Henrique , Paula José Realino de
Published: January 2023

Lippia lupulina Cham. and  Lippia pohliana Schauer are species of Verbenaceae used in folk medicine in the Brazilian Midwest. In order to identify the characteristics with taxonomic value that differentiate these species, the morphoanatomical characterization of the leaves and description of the chemical composition of the essential oils was carried out. The investigation of the anatomical characteristics of each species allowed the identification of different structural characters, related to the types of glandular and non-glandular trichomes, types of stomata, structural organization of the petiole's vascular system and the presence of sclereids in the petiole. Regarding the chemical composition of essential oil, in L. lupulina the main constituents were E-caryophyllene, caryophyllene oxide and dauca- 5,8-diene, while in L. pohliana, E-caryophyllene was the main constituent, followed by α-humulene and amorpha-4,7(11)-diene. Therefore, the results found have taxonomic value, as they allow the identification of species and help in the knowledge of the genus. And the characters studied contribute to future morphoanatomical, taxonomic and pharmacological studies.