bluuebunny/crossref_metadata_2025 huggingface dataset:
Standard Tree and Shrub Plants in the Landscape Design of the City of Kyiv: Current Condition and Perspectives of Use
Authors: Shvets Iryna , Rybalko Yuliya , Ternopolska Yanа
Published: November 2022

The purpose of the research is to summarize the information and evaluate the prerequisites for optimizing the taxonomic composition of plants for the general use plantations of the city of Kyiv. The work aims to provide specific proposals for the introduction of standard tree and shrub plants in the city’s public plantings, focusing on the motivation of plant selection based on ecological, biological and decorative features. Research methodology. In the process of conducting research, several special and generally scientific methods were used, including field survey, monitoring, description, analysis, synthesis, abstraction, generalization, comparison, forecasting and classification. The scientific novelty of the research consists in conducting an in-depth analysis of the modern taxonomic composition of standard tree and shrub plants, summarizing the condition and prerequisites for their use in the landscape design of Kyiv. Based on the results of the work, practical recommendations have been provided in the form of a specific list of standard tree and shrub plants, which are advisable to use in public plantations of the city, which confirms the practical significance of the conducted research. Conclusions. It has been established that modern landscape design trends, in particular, the use of standard tree and shrub plants, contribute to the improvement and modernization of public plantings in the city of Kyiv. The proposed list of these species’ plants aims to significantly enrich the taxonomic composition of green spaces and improve the urbanized space of the city. The motivation for the choice becomes quite clear given the decorative indicators of these plants, their biological and ecological stability, adaptability, dimensions (stem height, shape and size of the crown), safety and practicality of use in urban conditions. An essential enrichment of the standard tree and shrub plants’ taxonomic composition over the past decades has become possible thanks to active selection work abroad. Predictions in the field of landscape design and decorative horticulture testify to the planned changes in the system of green spaces in the city of Kyiv, including public spaces, under the influence of European experience.
Specifics of Design of Healthcare Institutions Interiors in the Conditions of the "COVID 19" Pandemic
Authors: Semyroz Nina , Lopukhova Natalya , Nikulina Daryna
Published: November 2022

The purpose of the article is to forecast, determine changes in the methodological basis for creating an interior environment by means of design in conditions of extremely uncertain requirements for the protection of the population from COVID-19. The research methodology involves the use of methods of generalization and systematization of scientific and theoretical information on the design of the environment in the context of the spread of coronavirus infection. The scientific novelty of the study is to clarify the features of interior design of healthcare institutions in the context of protection against coronavirus infections. Conclusions. Ukrainian healthcare sector found itself in an ambivalent state in late 2020, as the coronavirus raged relentlessly across the country, vaccination was developed quite slowly, therefore, being in public institutions, vulnerable population groups needed special safety conditions. Coronavirus-related expenses have already leveled a financial blow to healthcare system. Many hospitals lacked the space and resources to treat Covid-19 patients with severe symptoms, while treating those with mild and asymptomatic patients who could infect healthcare professionals and other patients. During the first wave of the virus pandemic, beds for patients were set up in lobbies, conference rooms and even cafeterias. They were added to the wards and corridors, filling any free space. The pandemic required the flexibility of medical and research institutions and services to overcome current and future crises.

As a result of the conducted research what specific design decisions should be considered when designing medical facilities in a pandemic. The peculiarities of creating safe, adapted, flexible and efficient spaces that support the quality of medical care and are resistant to infections on the example of foreign experience are highlighted. And research the basic regularities of pandemic-resistant healthcare design were identified: versatility, flexibility, aesthetics and harmony, safety and sterility, mobility and innovation. The interior should be focused on reducing the transmission of infectious particles.
The Effect of Altman Z-Score as Tool for Predicting Potential Bankruptcy on Stock Prices in Retail Subsector Companies Listed on the IDX in 2019 – 2021
Authors:   Politeknik Negeri Bali, Githayoni IGA Kade Amanda , Ardina Cening ,   Politeknik Negeri Bali, Wijana I Made ,   Politeknik Negeri Bali
Published: November 2022

The purpose of this study is to determine the Effect of Altman Z-Score as Tool for Predicting Potential Bankruptcy on Stock Prices in Retail Companies Listed on the IDX in 2019 – 2021. The data collection technique in this study uses documentation methods as well as literature studies published by the company. The data in this study uses financial statements published by retail sector companies listed on the Indonesia Stock Exchange in 2019 – 2021 by sampling using purposive sampling techniques. Companies that have met the sampling criteria are 11 companies. The data analysis method in this study uses Altman Z-score bankruptcy analysis, as well as for financial ratios using the ratio of Altman Z- score consisting of Working capital on total assets, retained earnings on total assets, profit before tax and interest on total assets, and book value of total equity at the book value of total liabilities. The next data analysis technique in this study used classical assumption tests, simple liner regression, and other hypothesis test tools. The results of this study showed that the Altman Z-score had a significant effect on the Stock Price of 17.7% with a calculated t value of 2.578 > 2.03951 (0.05 significant α) from the table. Based on the results of the Calculated Altman Z-score classification, it is shown that in 2021 there are 36 companies in a state of bankruptcy, 28% are in a state of gray area, and 36% are in a safe state.
Financial Ratio Analysis in Assessing Financial Performance of Denpasar City Government for the Year 2018 – 2021
Authors:   Politeknik Negeri Bali, Garbania Ida Ayu Putu Jyotisna , Bagiada I Made ,   Politeknik Negeri Bali, Putrayasa I Made Agus ,   Politeknik Negeri Bali
Published: November 2022

The execution of the standard of decentralization with regards to understanding the local independence of city in the Province of Bali has not been completely ready to investigate provincial pay sources which will uphold the outcome of carrying out territorial independence. Monetary information written in the Regional Government Budget isn't adequate to give sufficient data with respect to monetary administration execution in a specific locale. This exploration looked to evaluate the presentation of territorial monetary administration in Denpasar City during 2018-2021, as estimated by the local monetary reliance proportion, adequacy proportion, productivity proportion, the provincial consumption similarity proportion, the level of financial decentralization proportion and development proportion. Monetary Ratio Analysis utilizing the Budget Realization Report can be an estimating instrument for evaluating the monetary exhibition of nearby government. The exploration results uncovered that the monetary administration execution of Denpasar City during 2018-2021 still generally low in a few proportions explicitly the territorial monetary reliance proportion, productivity proportion, the level of monetary decentralization proportion and development proportion, while viability pro- portion and the local consumption similarity proportion show great monetary execution. It tends to be seen from its low territorial independence and its high reliance on the focal government. Furthermore, the territorial government has not had the option to smooth out the local funds in which provincial consumptions were more prominent than provincial incomes. The development pace of provincial monetary administration can be sorted as bad, since there is a lessening in pay consistently during the estimation time of the financial year.
Menguji Konsistensi Alat Ukur Penilaian Kinerja Anggaran Tingkat Satuan Kerja Pada Aplikasi “Smart DJA"
Authors: Santoso Arif Gunawan , Zakiah Zakiah , Dewi Rita Sukma
Published: November 2022

Salah satu nilai kinerja Lembaga/kementerian negara, diukur dari bagaimana ia mengelola keuangan negara. Berdasarkan Peraturan Menteri Keuangan Nomor 214/PMK.02/2017 tentang Pengukuran dan Evaluasi Kinerja Anggaran atas Pelaksanaan Rencana Kerja dan Anggaran Kementerian Negara/Lembaga, salah satu instrument penilaian kinerja Lembaga adalah Nilai Kinerja Anggaran (NKA). Terdapat empat instrumen yang digunakan untuk mengukurnya, yaitu variabel capaian keluaran, realisasi anggaran, efisiensi, dan konsistensi rencana penarikan dana. Tiga variable merupakan variable independent, sementara satu variable, yaitu efisiensi, merupakan variable terikat, yaitu variable efisiensi. Efisiensi terikat dengan nilai realisasi anggaran dan nilai capaian keluaran. Sebagai instrument penilaian kinerja, berbagai alat ukur tersebut harus memenuhi kriteria alat ukur yang konsisten dan relevan. Pada tahun 2020, terdapat anomali ketika ketiga variable bebas yang diperoleh oleh Balai Litbang Agama Semarang mendapatkan nilai tertinggi, namun nilai akhir yang dihasilkan, ternyata perolehan nilainya berada dibawah satker lain yang memiliki nilai lebih rendah. Penelitian dilakukan untuk menguji apakah mekanisme penilaian yang ditentukan oleh Kementerian Keuangan memenuhi kriteria sebagai alat ukur yang konsisten dan relevan. Penelitian dilakukan dengan pendekatan simulasi variasi nilai pada keempat variable dan dibandingkan dengan hasil akhir penilaian kinerja berdasrakan datasimulasi. Berdasarkan pengamatan data simulasi, ditemukan bahwa terdapat ketidakkonsistenan atas alat ukur yang ditentukan. Inkonsistensi terutama didapatkan pada mekanisme penentuan nilai efisiensi, yang berdampak pada tidak konsistennya nilai pada masing-masing variable terhadap nilai akhir kinerja anggaran. Karena itu, perlu peninjauan ulang metode/cara mengukur variabel efisiensi, sehingga tidak berdampak pada tidak konsistennya keseluruhan alat ukur kinerja anggaran.
Ilalang Arenna Haji Bawakaraeng:
Authors: Syamsurijal Syamsurijal
Published: November 2022

Haji Bawakaraeng selama ini telah menjadi istilah kontroversial dalam masyarakat Sulawesi Selatan. Istilah itu ditujukan kepada komunitas yang sering melakukan ritual di Gunung Bawakaraeng, khususnya pada bulan Zulhijah. Istilah tersebut seakan-akan menunjukkan adanya pelaksanaan haji yang aneh dan menyempal dari kelaziman. Jika biasanya masyarakat pada umumnya melakukan ritual haji di Mekkah, maka di Sulawesi Selatan ada sekelompok orang yang justru melakukannya di puncak Bawakaraeng. Tetapi komunitas itu sendiri tidak merasa sedang melakukan haji sebagaimana pelaksanaan haji di Mekkah. Mereka yakin haji ke Mekkah tidak bisa digantikan dengan naik ke Bawakaraeng. Hanya saja soal mendapatkan pahala haji, tempat sering kali tidak menjadi soal. Tulisan ini bertujuan untuk mengungkapkan mengapa bisa mereka digelari Haji Bawakaraeng dan bagaimana sikap mereka dalam merespons pelabelan tersebut. Melalui penelitian kualitatif, ditemukan, istilah Haji Bawakaraeng adalah konstruksi orang di luar komunitas Bawakaraeng untuk memberikan label negatif terhadap ritual yang sering dilakukan di Gunung Bawakaraeng. Pelabelan itu adalah upaya kelompok Islam tertentu untuk menyingkirkan komunitas yang secara resmi beragama Islam, tetapi dipandang oleh kalangan tersebut masih sering melakukan perbuatan khurafat dan kemusyrikan. Tetapi yang menarik, meski ada di antara komunitas Bawakaraeng yang menolak istilah itu tetapi secara umum mereka justru menggunakannya. Mereka menggunakan istilah tersebut sebagai identitas. Melalui identitas Haji Bawakaraeng itulah mereka lalu membangun diskursus baru tentang haji. Cara mereka memberi makna baru terhadap Haji Bawakaraeng di tengah pelabelan negatif masyarakat adalah sebuah permainan identitas melalui sebuah nama.
Mappanre temme’: Sisi Eksotis Akulturasi Budaya di Kecamatan Belawa Kabupaten Wajo
Authors: Waris Abdul , Ahmad Hadiah
Published: November 2022

Tradisi Mappanre temme’ adalah salah satu tradisi turun temurun yang dilaksanakan oleh masyarakat di Kecamatan Belawa setelah anak-anaknya mengkhatamkan bacaan Al-Qur’annya sebanyak 30 Juz. Pada dasarnya, tradisi ini juga dilaksanakan di sejumlah daerah, namun tradisi ini mengalami pergeseran nilai sosial di Kecamatan Belawa, di antaranya dengan pelaksanaannya yang tidak lagi mengikut pada acara lainnya. Hal ini menjadi menarik untuk meneliti perubahan-perubahannya dan hal yang mendasarinya, serta nilai yang dikandungnya. Penelitian ini menggunakan metode kualitatif deskriptif untuk melihat eksistensi dan keunikan tradisi Mappanre temme’, serta mengurai nilainilainya sebagai sebuah hasil akulturasi. Metode yang digunakan untuk mengumpulkan data adalah dengan wawancara, observasi, dan dokumentasi. Penelitian ini menunjukkan bahwa masyarakat Bugis di Kecamatan Belawa masih mempertahankan keberadaan tradisi Mappanre temme’, bahkan cenderung melahirkannya sebagai tradisi yang mewah dan berkelas. Pergeseran nilai sosialnya tampak dari proses pelaksanaannya, yakni berdiri sendiri, penggunaan pakaian adat yang mewah dan komplit, pengadaan menu dan resepsi mewah, dan pengadaan musik hiburan. Sebagai dampaknya, tradisi Mappanre temme’ terlihat sangat unik dan eksotis ketika dilaksanakan secara sendiri, tanpa mengikut pada acara lain. Mappanre temme’ pada akhirnya menjadi simbol kelas sosial di masyarakat Kecamatan Belawa.
Pengislaman Federasi Duri Abad XVII
Authors: Hadrayani Ira , Mukarramah Mukarramah , Karim Abd.
Published: November 2022

Federasi Duri sering kali kurang dilirik oleh akademisi terutama dalam kajian Islam. Sementara itu, wilayah ini juga cukup penting dalam perkembangan sejarah Sulawesi Selatan. Keberadaan Federasi Duri sering kali tidak terbaca pada beberapa kajian. Disisi lain, Federasi memiliki perjalanan panjang mulai dari fase tomanurung, kerajaan, masuknya Islam, Kolonialisme sampai revolusi. Artikel ini membahas tentang Federasi Duri dan berfokus pada kajian pengislaman wilayah ini. Melihat bagaimana proses Islamisasi Federasi Duri? Penyebaran Islam di Duri menempuh jalur apa? Kedua pertanyaan ini sangat penting karena proses pengislaman membutuhkan media dalam penyalurannya. Federasi Duri dalam beberapa catatan, bersentuhan dengan Islam pada 1608. Persentuhan Islam dan Federasi Duri dapat dilihat dari posisi wilayah ini yang berada dibawah kekuasaan Kerajaan Luwu. Pada mulanya, wilayah ini tidak menerima Islam sepenuhnya namun faktor ekonomi dalam hal ini hubungan dagang dan faktor politik Federasi Duri akhirnya tercatat memeluk Islam pada Selasa 2 Sya‟ban (17 Juni 1687). Posisi Duri berada di jalur perdagangan Bone-Sidenreng-Duri-Toraja dan pada tahun tersebut telah menjadi wilayah fasal dari Kerajaan Bone. Hasil kajian tersebut ditemukan dengan menggunakan metode penelitian sejarah yang terdiri dari heuristik, kritik, interpretasi dan historiografi. Data diperoleh dari penelusuran Arsip Kolonial Belanda dan sumber sejarah yang berhubungan langsung dengan objek kajian baik primer maupun sekunder. Kata kunci: federasi duri, islam, pengislaman, perdagangan, politik
Ekspresi Tazkiyah al-Nafs dalam Pappaseng
Authors: Susmihara Susmihara , Nuraeni Nuraeni , M M. Dahlan , Yani Ahmad
Published: November 2022

Tulisan ini mengkaji tentang pappaseng Bugis yang merupakan ekspresi dari tazkiyah al-nafs dalam tasawuf yang mengandung nilai-nilai kebajikan. Pappaseng sebagai sebuah genre puisi dalam sastra Bugis secara subtansi memiliki relevansi dengan nilai-nilai Islam. Penelitian diawali dengan pemerolehan teks pappaseng yang dilakukan melalui sumber pustaka kemudian dipadukan dengan sumbersumber lisan. Analisis yang diterapkan menggunakan pendekatan antropologi agama yang bermaksud untuk mengungkap nilai-nilai kebajikan kehidupan yang terkandung dalam teks-teks pappaseng. Hasil pengkajian menunjukkan bahwa, narasi pappaseng yang berkembang dalam masyarakat Bugis memiliki keselarasan dengan nilai-nilai Islam yang mencakup tiga aspek yaitu „tawakkal‟ yang di dalam pappaseng Bugis disebut pesona (pasrah kepada Tuhan); ukhuwah dalam pappaseng Bugis disebut assimellereng (persaudaraan); dan; shiddiq dalam pappaseng Bugis disebut lempu (jujur).
Nilai Simbolik Rumah Adat Caile dalam Studi Budaya
Authors: Nur Haerani , Syukur Syamzan , Mastanning Mastanning
Published: November 2022

Penelitian ini bertujuan untuk menjelaskan mengenai rumah adat Caile di Desa Pao Kecamatan Tombolo Pao Kabupaten Gowa dalam Perspektif Budaya. Penelitian ini menggunakan jenis penelitian kualitatif dengan menggunakan Field Research berupa hasil wawancara, observasi langsung ke lokasi dan Library Research sebagai data pendukung yaitu mencari sumber-sumber secara tertulis yang berkaitan dengan penelitian. Hasil penelitian menunjukkan bahwa: pertama, Caile dibagun oleh Dampangia pada tahun 1468 atau pertengahan abad 15 M. Rumah adat Caile merupakan rumah pertama yang dibangun di wilayah itu dan setiap orang yang lewat akan menoleh sehingga nama Caile diambil dari bahasa Konjo yaitu Assaile yang berarti menoleh. Kedua, fungsi rumah adat Caile pada masa kerajaan hingga masa modern, Rumah adat Caile difungsikan sebagai tempat pelantikan raja dan orang-orang yang dipercaya sebagai pelaksana tugas pemerintahan namun pada masa modern ini Caile tidak lagi menjadi tempat pelantikan raja. Ketiga, nilai-nilai yang terkandung dalam rumah adat Caile sebagai salah satu warisan budaya yang ikonik bagi masyarakat Pao memberikan pengaruh pada pola hidup masyarakat. Oleh karena itu, rumah adat tersebut perlu dijaga dan dipertahankan. Keyakinan masyarakat terhadap kesakralan rumah adat tersebut membuat keberadaannya menjadi salah satu warisan budaya terpenting di desa Pao Kecamatan Tombolo Pao Kabupaten Gowa.
TARİHÎ DÖNEM TÜRKÇE KUR’AN TERCÜMELERİNDE DEYİMLER: FATİHA VE BAKARA SURELERİ
Authors: ÇETİN Engin
Published: November 2022

Bu çalışmada Türkçenin en eski Kur’an tercümelerindeki deyimler ilk iki sure olan Fatiha ve Bakara surelerinde tespit edilerek karşılaştırmalı bir şekilde incelenmiştir. Çalışmada TİEM 73 numarada kayıtlı olan, 1334 tarihinde istinsah edilmiş Kur’an tercümesi esas alınmış, buradaki deyimler Özbek İlimler Akademisi Kur’an tercümesi (ÖİAKT) Harezm Türkçesi Hekimoğlu Kur’an tercümesi (HKT) ve Eski Anadolu Türkçesine ait iki Kur’an tercümesiyle (EAT (Bursa), EAT (Manisa)) karşılaştırmalı olarak incelenmiştir. Deyimlerin tespitinde TİEM 73 numaralı Kur’an tercümesinin esas alınmasının sebebi, eldeki yazmanın tama yakın bir nüsha olmasıdır. John Rylands nüshasının baştan ve sondan eksik olması nedeniyle bu nüsha deyimleri belirlemeye esas olarak tercih edilmemiştir. Tespit edilen deyimlerin Kur’an-ı Kerim’de hangi sözün veya ibarenin karşılığı olarak kullanıldığı, bu söz veya ibarenin Kur’an-ı Kerim’in başka yerlerinde kullanılıp kullanılmadığı, kullanıldıysa Türkçe Kur’an tercümelerinde ne şekilde karşılandığı, Türkçe deyimlerin tercümenin başka yerlerinde hangi söz veya ibarenin karşılığı olarak kullanıldığı ve tespit edilen deyimlerin Tarihî Türk yazı dillerindeki durumları üzerinde ayrıntılı olarak durulmuştur. Türkçe en eski Kur’an tercümelerinin Farsçadan çevrildiği düşünüldüğünde Farsçanın söz konusu deyimler düzeyinde tercümeye etkisi de çalışmada akılda tutulan sorulardandır. Daha önce birçok araştırmacının değindiği, en eski Kur’an tercümelerinin birbirlerinden veya aynı tercümeden istinsah edilmiş olabileceği düşüncesi de çalışmada deyimler açısından ele değerlendirilmiştir.

Çalışmanın sonucunda, incelenen yirmi altı deyimin çoğunluğunun Türkçeye bire bir tercüme edilmekle birlikte dokuz deyimin serbest çeviriyle Türkçeye aktarıldığı, bu dokuz deyimin bir bölümünün Kur’an tercümelerinden önceki ve sonraki dönem metinlerinde de tespit edildiği görülmüştür.
Modern İran Öykü Yazarı Golî Terakkî’nin “Bir Başka Yer (جای دیگر)” Adlı Öyküsünde Anlatım Teknikleri
Authors: EREN SOYSAL Esin
Published: November 2022

Edebiyat dünyasında sanatçı, duygu ve düşüncelerini çeşitli anlatım teknikleriyle edebî eserlerinde ortaya koyar ve okuyucuya sunar. Bu anlatım teknikleri ile yeni bakış açıları geliştirerek eserinde kendine has bir anlatım tekniği kullanır. Özellikle modern edebiyat anlayışıyla öykü türünün gelişim sürecine bakıldığında anlatım teknikleri çeşitlilik göstermektedir. Bu çalışmada modern İran edebiyatının 50’li ve 60’lı yıllarında öne çıkan kadın yazarlarından olan ve eserlerinde hayatın içinden kahramanlara sıklıkla rastlanılan Golî Terakkî tarafından kaleme alınan Bir Başka Yer (جای دیگر) adlı öykü, anlatım teknikleri bakımından değerlendirilecektir. Mevcut çalışmada Bir Başka Yer (جای دیگر) adlı öykünün anlatıcısı ve onun bakış açısı çevresinde bireyin iç çözümlemeleri, aklından geçenler, aile ve toplum ilişkileri, yaşama dair düşünceleri, hayatın içindeki duruşu anlatma esasına bağlı anlatım teknikleri ile betimlenecektir. Çalışmada yöntem olarak özellikle “anlatma”, “tasvir”, “geriye dönüş”, “leitmotiv” ve “İç çözümleme” gibi anlatım teknikleri ele alınıp, bu anlatım teknikleri öyküden verilecek örneklerle desteklenecektir. Çalışmada incelenecek bu anlatım teknikleri ile öykünün çeşitli bakış açıları ile tekrar gözden geçirilmiş olması ve okuyucunun farklı bir bakış açısı elde etmesi amaçlanmaktadır. Dolayısıyla yazarın eserinde vermek istediği mesajın okuyucusuna daha etkili bir şekilde ulaştırılması sağlanacaktır.
Thiol-dependent mechanisms of selenium-containing preparations and thiolylfluanide effect on electrolytes leaching and peroxidase activity in Zea mays L.
Authors: Poluboyarinov P. A. , Shchetinina N. V. , Moiseeva I. Ya. , Mikulyak N. I. , Golubkina N. A. , Kaplun A. P.
Published: November 2022

Objectives. While organic and inorganic derivatives of selenium like thiol poisons are known to activate enzymes in cells of different organisms, the mechanism of enzyme activity induction is poorly studied. Therefore, the aim of the study was to investigate the effect of selenium compounds on peroxidase activity induction in maize tissues.Methods. Mechanism of sulfhydryl groups blocking in selenium derivatives was studied on maize in comparison with fungicide tolylfluanid—a typical thiol poison. Electrolytes leakage was determined using conductometry and capillary electrophoresis, protein fractions—by the Ermakov–Durinina method, protein concentration—according to Bradford protein essay, and peroxidase activity—by the Boyarkin method.Results. Diacetophenolylselenide (DAPS-25) was shown to react with SH-groups similarly with tolylfluanid fungicide. DAPS-25 increased K+ and leakage by 58 and 14 times, while appropriate increases for tolylfluanid were 4.4 and 1.5 times as compared to control. Increased total protein content—especially albumins—was due to electrolyte leakage from maize cells. DAPS-25 increased albumins concentration by 2.4–4.5 times, and tolylfluanid application by 2 times. Similar increase of peroxidase activity in maize roots and sprouts as a result of DAPS-25 (by 63% and 112%) and tolylfluanid (by 73% and 63%) application indicates close mechanism of their effect. Under DAPS-25 loading L-cysteine decreases peroxidase activity, which records the removal of SH-groups blockage. A less intensive effect was registered for sodium selenite and L-selenocystin, also capable of reacting with SH-groups. L-cysteine supplementation to DAPS-25 solution decreases selenium concentration in maize, indicating the decrease of selenium bioavailability.Conclusions. The results indicated that selenium containing compounds react with SH-groups of maize cells increasing electrolytes leakage, protein content and especially albumins resulting in the increase of peroxidase activity.
Interaction of the anion [2-B10H9O(CH2)4O]− with secondary amines
Authors: Matveev E. Yu. , Novikov S. S. , Levitskaya V. Ya. , Nichugovskiy A. I. , Sokolov I. E. , Zhizhin K. Yu. , Kuznetsov N. T.
Published: November 2022

Objectives. One of the most promising methods of treating malignant tumors is 10B-neutron capture therapy. While compounds based on cluster boron anions [BnHn]2− (n = 10, 12) are often used as boron-containing agents due to the very high specific concentration of boron atoms per particle, the use of such compounds is associated with the need to develop new methods for the functionalization of boron clusters associated with the production of boron-containing derivatives containing biologically active functional groups. One of the most convenient methods of modification of [BnHn]2− (n = 10, 12) anions is the interaction of their derivatives containing cyclic oxonium-type substituents with negatively charged or neutral nucleophilic reagents. The disclosure of substituents of this type leads to the formation of closo-borates with functional groups separated from the cluster by an alkoxyl spacer chain. The purpose of this study is to develop methods for the synthesis of derivatives of the closo-decaborate anion [B10H10]2− with pendant nitrogen-containing groups.Methods. The general control of the reactions of the disclosure of cyclic substituents was carried out on the basis of 11B nuclear magnetic resonance (NMR) spectroscopy data. The structure of the obtained derivatives, including the nature of the attached functional groups, was determined using 1H, 13C attached proton test (APT) NMR and infrared (IR) spectroscopy data. The molecular weight of the synthesized compounds was confirmed by electrospray ionization mass-spectrometry (ESI–MS).Results. The interaction of the anion [2-B10H9O(CH2)4O]− with secondary amines (dimethylamine, dipropylamine, diallylamine, dibutylamine, diisobutylamine, morpholine, di-sec-butylamine) in an ethanol environment is investigated. As a result of the reactions, a cyclic substituent is shown to expand with the addition of a nucleophilic reagent. Seven new derivatives of the closodecaborate anion with pendant nitrogen-containing groups have been synthesized.Conclusions. A developed method for obtaining closo-decaborates with ammonium groups separated from the boron cluster by an alkoxyl spacer group is presented. It is shown that the use of amines of various structures does not fundamentally affect the course of the reactions, allowing the composition and structure of the target derivatives to be effectively regulated. The resulting compounds can be involved in further modification reactions due to a reactive pendant group, as well as being suitable for use as effective polydentate ligands. Closo-decaborates with pendant nitrogen-containing groups and their derivatives are of considerable interest in the synthesis of compounds for use in 10B-neutron capture therapy of malignant tumors.
Cell viability and collagen metabolism of MCF-7 breast cancer cells are affected by carbon monoxide released from CORM-2.
Authors: Sawicka Magdalena , Drągowski Paweł , Stelmaszewska Joanna , Prokop Izabela , Sawicki Karol , Polityńska Barbara , Miltyk Wojciech
Published: November 2022

Carbon monoxide (CO), despite its reputation as a deadly poison, is being recognized as a powerful physiological regulatory agent with potential anti-cancer properties. To harness the potential of CO towards a safe therapy, CO-Releasing Molecules (CO-RMs) have been developed. In the present study, the effects of tricarbonyldichlororuthenium(II) dimer (CORM-2) on MCF-7 breast cancer cell cultures were evaluated, with particular regard to mechanisms affecting collagen biosynthesis. In our model, CORM-2 exerted dose-dependent cytotoxic and antiproliferative effects, i.e., attenuated cell viability, induced apoptosis and reduced autophagy. Collagen biosynthesis was significantly reduced, with signs of the involvement of nuclear factor kappa B, integrin β1, insulin-like growth factor 1 and proline metabolism as the probable underlying mechanism. No effects of CO-depleted CORM-2 were found, thereby demonstrating that CORM-2 activity is associated with carbon monoxide. Additionally, it was found that CORM-2 had no influence on control fibroblasts cultures.
Our results confirm both the cytotoxic and collagen-related properties of CO-releasing molecule in a breast cancer cell culture, and therefore serve to encourage further research in a pre-clinical setting. To the best of our knowledge, this study is the first to attempt to relate the effects of CORM-2 on cell viability and collagen metabolism in a cancer cell culture.
Hypoxia- Inducible Factor-1α promotes the therapeutic effect of Astragaloside IV on hypertension
Authors: Hou Yiling , Chai Cijing , Wang Shufang
Published: November 2022

Objective To explore the effect of HIF-1α on the cardiovascular protective effect of Astragaloside IV. Method To divide the mice into four groups, hypertension model group (LC), Astragaloside IV treatment group (LR), HIF-1α overexpression combined with Astragaloside IV treatment group (LO), HIF-1α knockdown combined with Astragaloside IV treatment group (LK), and measure the mean blood pressure of mice at day 1, day 7, day 14 and day 21. Then, the aortic tissue sample was collected, the expression of HIF-1α related signaling pathway molecules were detected using western blot and qPCR method. The concentration of vascular protective molecules was detected using ELISA method. Results The mean blood pressure in LO group was significantly decreased, while the JAK/STAT3/HIF-1α signaling pathway was significantly activated, and the expression of anti-apoptosis and vascular protection molecules was increased. Besides, the concentration of vascular protection molecules was significantly increased in blood sample. Conclusions Overexpression of HIF-1α significantly activated the JAK/STAT3 signaling pathway, increased the expression and the concentration of vascular protection related molecules, enhanced the cardiovascular protective effect of Astragaloside IV.
Artificial neural networks and their application in the optimization of carbamazepine solid dispersions
Authors: Vojinovic Tanja , Potpara Zorica , Vukmirovic Mihailo , Turkovic Nemanja , Ibric Svetlana
Published: November 2022

The aim of this study was to examine the possibility of using artificial neural networks in the optimization of solid dispersions with carbamazepine. Artificial neural networks of the Generalized regression neural network type with four layers, gave models that describe the effect of components in solid dispersions carbamazepine-Neusilin ® UFL2 (magnesium aluminosilicate)-Collidon ® VA64 (vinylpyrrolidone-vinyl acetate) and dissolved carbamazepine value (%) after 10 (Q10) and 30(Q30) minutes of carbamazepine testing. After the learning process, root mean square error (RMS) values of 0.0029 were obtained for the training data set, and 0.1185 for the test training data, which is an excellent prediction of the neural network.
Release of salicylic acid from new multiphase bases with consideration of the preparation method
Authors: Bułaś Lucyna , Szulc - Musioł Beata , Siemiradzka Wioletta , Służalec Małgorzata , Dolińska Barbara
Published: November 2022

Abstract: The study evaluated the release of salicylic acid with new two multiphase ointment bases: Fitalite™ and Nourivan™ Antiox. Fitalite™ is a cream-gel base while Nourivan™ Antiox is a cream oil in water. Salicylic acid is a substance often used in the formulation of semi-solid dosage forms applied on the skin. The release rate of salicylic acid was examined depending on the base and the particle size of the active ingredient. For this purpose, formulations containing 5% salicylic acid were prepared and used for the study. Three different methods were used for the incorporation of salicylic acid into the bases: non-grinded, ground with the base for 15 minutes, and concentrate of salicylic acid with white soft paraffin (1:1). Measurements of the particles of the active substance in each of the preparations were also taken. Salicylic acid has been shown to be released to a greater extent from Fitalite ™ base. Qualitative analysis of the composition of the bases, in studies conducted by the Department staff, allows concluding that the amount and release rate of salicylic acid from the bases is influenced by its viscosity. This parameter has a significant impact on the level of trituration of salicylic acid. It was also found that the concentrate of salicylic acid with white soft paraffin (1:1) reduces the time of preparation of a suspension type ointment with salicylic acid, wherein the particle size accomplishes the requirements of pharmacopeia.
Konvergálnak vagy divergálnak az Európai Unió tagországai demográfiai szempontból?
Authors: Drabancz Áron
Published: November 2022

Tanulmányunkban az Európai Unióhoz régebben és 2004 után csatlakozó tagországok demográfiai folyamatait vetettük egybe a teljes termékenységi arányszám, a várható élettartam, a nettó migráció, illetve az időskori függőségi ráta változókkal. Az újonnan csatlakozó tagországok demográfiai kilátásai borúsak, a nagymértékű kivándorlás és az alacsony teljes termékenységi arányszám miatt az elöregedési problémák összességében fokozottabban érvényesülhetnek a 2004 után csatlakozó tagállamok körében, mint a korábban csatlakozók esetében. Klaszterelemzésünk kimutatta, hogy az újonnan csatlakozó tagországok mind 2004-ben, mind napjainkban a vizsgált demográfiai változók tekintetében bizonyos mértékben elkülönülnek a centrumországok értékeitől, azonban a klaszterek stabilitása az alkalmazott metódusok függvényében viszonylag alacsony.
Sprawa wydalenia Szalwy Amiredżibiego
z Polski w 1931 roku
Authors: Chikhoria Razhden
Published: November 2022

Na podstawie materiałów archiwalnych autor przedstawia mało znane karty z historii ruchu prometejskiego, mianowicie kulisy wydalenia z Polski gruzińskiego publicysty i działacza partii nacjonaldemokratycznej, Szalwy Amiredżibiego. Mimo że Amiredżibi był aktywnie zaangażowany w działalność ruchu prometejskiego, jednak wiosną 1929 roku zerwał współpracę z polskim obozem i nawiązał kontakt z opozycją. Autor tłumaczy kontekst i przyczyny tych wydarzeń. W październiku 1930 roku, Amiredżibi przybył do Polski z nieznanym nikomu celem. Przebywając w Polsce przez trzy miesiące uczestniczył on w różnych tajnych zebraniach zwolenników oraz członków obozu gruzińskich nacjonaldemokratów. Gruziński rząd emigracyjny w Paryżu i jego przedstawiciele w Warszawie obawiali się, że ich rywale polityczni obmyślają plan przejęcia steru władzy w gruzińskiej kolonii w Polsce. Na prośbę strony gruzińskiej czynniki polskie podjęły decyzję o tym, by nie przedłużać wizy ani Sz. Amiredżibiemu, ani drugiej osobie powiązanej z obozem nacjonaldemokratów, Wacznadzemu. Obydwaj zostali poproszeni o opuszczenie terytorium Rzeczypospolitej. Prawdopodobnie prośba ta została przez nich zignorowana, po czym Sz. Amiredżibi został aresztowany i przymusowo wydalony z Polski. Autor skupia się na analizie kryzysu, konfliktów personalnych wśród gruzińskiej emigracji, które miały wpływ na decyzję polskich władz.
A in (eficácia) da lei 13.344/2016 no âmbito de prevenção e punição ao crime de tráfico humano
Authors: Silva Luis Henrique Couto , Lima Caroline Moreira , Frazão Camila Giovana Xavier de Oliveira
Published: November 2022

Objetiva-se, através da presente pesquisa científica, tratar acerca da ineficácia da Lei 13.344/2016 quanto à estipulação de medidas de prevenção e repressão ao crime de tráfico humano. É sabido que o tráfico de pessoas se constitui como uma das maiores preocupações da atualidade, haja vista que afeta a vida de milhares de pessoas ao redor do mundo, conduzindo-as para um mundo de exploração, de cerceamento da liberdade e da aniquilação da dignidade humana. Desse modo, observa-se se o Brasil, país signatário do Protocolo de Palermo, cumpre com todas as medidas, diretrizes e preceitos necessários ao combate ao crime de tráfico humano e, concomitantemente, estabelece medidas de prevenção ao mencionado delito. Com base nos resultados auferidos, coaduna-se com o posicionamento de que a Lei nº 13.344/16 mostra-se um importante avanço no combate ao crime de tráfico humano, estabelecendo medidas preventivas, repressivas e de proteção às vítimas. Ademais, demonstra-se, através da referida Lei, alterações importantes no Código Penal Brasileiro, onde passou-se a estipular novas modalidades de tráfico humano que antes não eram consideradas. Contudo, embora tal diploma legal constitua como um importante passo em detrimento do crime de tráfico humano, o mesmo ainda se mostra ineficaz, haja vista os altos índices de pessoas brasileiras que se encontram nessa realidade. Dessa forma, mister que as autoridades públicas unam esforços em prol de novos mecanismos legais em prol de uma maior abrangência do crime em análise e, principalmente, que se instituam mecanismos de coleta de informações para se prevenir o cometimento de tal delito em âmbito nacional. Com relação à metodologia, enfatiza-se a utilização de mecanismos bibliográficos, doutrinários, jurisprudenciais e também o conteúdo presente em artigos científicos e periódicos, para fins de refinamento e alinhamento dos resultados da pesquisa.
Islamic Fiqh Views on E-Commerce
Authors: Nahlah  , Lutfi Mukhtar , Lutfi Mukhtar , Nasrullah Bin Sapa
Published: November 2022

The development of e-commerce continues to increase from year to year following the development of information and communication technology. E-commerce has had a significant impact on various sectors. E-commerce can reduce the flow of human traffic but increase the flow of goods traffic. In the modern era, humans have felt comfortable with this e-commerce. Just by being at home, various types of needs can be ordered through an online application and the items needed arrive at the buyer's house. For companies, e-commerce can improve efficiency and productivity. For the community, e-commerce can help increase economic growth and business opportunities. But at the same time, it poses challenges and problems in terms of security and trust. And is e-commerce not against Islamic law? This study examines how Islamic fiqh views e-commerce or online shop businesses whose data is obtained from related journals in 2012 – 2022. The method used in this study is the Systematic Literature Review (SLR) method. The SLR method is used to identify, review, evaluate, and interpret all available research with topic areas of interest to phenomena, with specific relevant research questions. The result is e-commerce is identical to the as-salam trade (buying and selling in fiqh muamalah), namely the purchase of goods received after payment is made up front in cash and is considered to meet the requirements of as-salaam.
Association of Prostate Cancer and Lipid Profile: A Case-Control Study
Authors: McGrowder Donovan , Coard Kathleen , Aiken William , Gibson Tracey , Morrison-Blidgen Belinda , McFarlane Shelly , Mayhew Richard
Published: November 2022

There are inconsistent findings concerning the association between the serum concentrations of lipid parameters and prostate cancer (PCa), particularly in Caucasian men. There is limited data on men of African ancestry. The study examined the relationship between serum total cholesterol (TC) levels and its fractions and PCa in a hospital-based case-control study in Jamaica. The serum levels of TC, triglycerides (TG), HDL-cholesterol (HDL-C), and LDL-cholesterol (LDL-C) in 46 male patients (cases) who underwent prostate biopsy were measured over an eighteen month period. There were 32 patients without PCa who served as controls. The serum lipid concentrations between cases and controls were compared using an independent samples t-test. Multiple linear regression and binary logistic regression were used to assess the relationship between lipids and overall PCa, as well as disease severity. Based on the results, there were no significant differences between the concentrations of lipids for the cases and controls. The results of the regression analysis revealed that the serum lipid levels were not significant predicators of overall PCa. The outcomes of the binary regression analysis showed the same for PCa severity. The study concluded that there was no association between serum levels of lipids and overall PCa as well as disease severity at the time of diagnosis in the sample of Jamaican men.
Studi Efek Skala pada Uji Kuat Tekan Uniaksial Terhadap Batupasir Pada Formasi Balikpapan Daerah Samarinda Utara, Provinsi Kalimantan Timur
Authors: Milda Milda , Trides Tommy , Hasan Harjuni , Oktaviani Revia , Winarno Agus
Published: November 2022

Scale effect testing on rocks is carried out with the aim of knowing the strength of a rock based on different dimensions. This test was carried out using a uniaxial compressive strength test and also testing the physical properties of rocks. In the rock compressive strength test used 5 dimensions of rock samples with a H/W ratio of which are 4.5/3, 6/3, 7.5/3 for dimensions of 3 cm, 5.25/3.5, 7 /3.5, 8.75/3.5 for dimensions 3.5 cm, 6/4, 8/4, 10/4, for dimensions 4 cm, 6.75/4.5, 9/4.5, 11.25/4,5 cm for the 4.5 cm dimension and for the 5 cm dimension, namely 7.5/5, 10/5 and 12.5/5. Physical properties testing is carried out to determine the porosity value in the test rock samples, which will then be compared between the porosity values ​​and the results of the compressive strength test of rock samples. Physical properties testing carried out obtained the average value of rock porosity, namely 22.562%, 22.122%, 20.454%, 21.227%, and 22.413%. In the scale effect test, it is known that the higher the rock sample, the smaller the value of the rock strength can be seen based on the R2 value obtained in the Balikpapan Formation, which is 0.0548.
Viscoelastic Dynamic Response of Asphalt Pavement in Long Slope Sections
Authors: Gao Yuanyuan , Dong Shuai , Xiao Han , Hlupo Nkosilathi lovewell , Liu Zhi
Published: November 2022

To deeply understand the performance of asphalt pavement in long slope sections, the object of this paper is to obtain the viscoelastic dynamic response of asphalt pavement in long slope sections considering interface bonding conditions. An asphalt pavement model is built, and then for solving the problem, the Laplace-Hankel transformation is used to transfer the partial differential equations to the ordinary differential equations. Transfer matrices are adopted to present the relationship of stress and displacement between the pavement surface and any pavement depth, and a special transfer matrix characterizes the interface bonding condition. By this method, the analytical solution of the stress and displacement at any pavement position is received. After that, an example of asphalt pavement in a long slope section is introduced considering the distribution of stress and displacement, the magnitude of the horizontal load, and the interface bonding strength. The horizontal vehicle load affects the distribution of shear stress τrz in the pavement. The interface bonding strength is more important in long slope sections than in any other normal section of asphalt pavement.
Distribusi Batubara dalam Memenuhi Kebutuhan Bahan Bakar PLTU Wilayah Kalimantan Barat
Authors: Sartika Sartika , Wahyudi Eka
Published: November 2022

Kalimantan Barat merupakan wilayah yang sebagian besar pasokan listrik bersumber dari pembangkit listrik dengan bahan bakar minyak. PT PLN melakukan percepatan pembangunan pembangkit listrik yang tersebar di seluruh wilayah Indonesia di mana program tersebut telah menghasilkan beberapa PLTU Eksisting di wilayah Kalimantan barat diantaranya adalah PLTU Sintang, Sanggau, dan Khatulistiwa. Mengingat bahwa di Provinsi Kalimantan Barat belum terdapat perusahaan yang memproduksi batubara, sehingga batubara untuk bahan bakar PLTU harus dipasok dari provinsi lain. Perbedaan jarak antar setiap pemasok batubara dan spesifikasi batubara yang dihasilkan oleh perusahaan memberikan kontribusi biaya pengadaan batubara yang berbeda pula. Hal tersebut mencerminkan bahwa terdapat keterbatasan sumber daya dan batasan sistem yang dapat dimodelkan dari permasalahan ini. Dalam menentukan pemecahan masalah yang bertujuan untuk memaksimumkan atau meminimumkan sesuatu dengan batasan-batasan tertentu digunakan teknik optimasi yang dikenal dengan metode Linear Programming. Untuk itu pada penelitian ini dilakukan kajian terhadap distribusi batubara untuk kebutuhan PLTU dengan biaya pengadaan yang paling minimum serta menjamin ketersediaan pasokan listrik di Provinsi Kalimantan Barat. Berdasarkan output dari Linear Programming, untuk memperoleh biaya pengadaan batubara minimum pada PLTU Sintang, Sanggau dan Khatulistiwa, batubara dapat dipasok dari PT. Adaro Indonesia.
Rancang Bangun Electric Power Converter (Catu Daya) Untuk Alat Anodizing Portable
Authors: Purwanto Sugeng
Published: November 2022

Electric Power Converter is an electrical device that provides a voltage source for other electrical devices by changing the voltage level to the desired voltage, AC to DC. The Electric Power Converter is to drain and regulate the voltage to be stable, which is important in the anodizing process. Its functions to flow DC during the anodizing process which requires variations in voltage and current, the greater the voltage and current, the thicker the oxide layer that occurs on the aluminum surface and the hardness will increase. This research has 4 stages. The design stage, which is a design process that includes specifications of shape, material, and tolerance as well as component standards. The component identification stage is the process of collecting data needed in designing, including the value, function, and type of component. The assembly stage is the process of compiling and unifying components according to the design and identification results. The testing aims to determine the quality of the tools that have been made, including testing the voltage and current. The Electric Power Converter in this study produces a voltage in the range between 0 - 250 VDC and has a stable voltage and current output.

Keywords: Electric Power Converter, Power Supply, Design, Anodizing.

 

 ABSTRAK

Electric Power Converter (Catu Daya) merupakan alat listrik yang menyediakan sumber tegangan untuk perangkat listrik dengan cara mengubah tingkat tegangan listrik yang tersedia menjadi tegangan yang diinginkan, tegangan AC menjadi DC. Electric Power Converter berfungsi untuk mengalirkan dan mengatur tegangan yang masuk ke perangkat elektronik menjadi stabil. Electric Power Converter memegang peranan penting dalam proses anodizing yaitu berfungsi untuk mengalirkan arus DC selama proses anodizing yang membutuhkan variasi tegangan dan arus searah, semakin besar tegangan dan arus maka semakin tebal lapisan oksida yang terjadi di permukaan aluminium dan kekerasannya (hardness) juga akan meningkat. Penelitian ini dilakukan dalam empat (4) tahap yaitu tahap perancangan, merupakan proses perancangan alat yang mencakup spesifikasi lengkap dari bentuk, material dan toleransi serta standar komponen. Tahap identifikasi komponen adalah proses pengumpulan data yang dibutuhkan dalam merancang electric power converter, mencakup nilai, fungsi dan jenis komponen. Tahap perakitan merupakan proses penyusunan dan penyatuan komponen sesuai desain dan hasil identifikasi. Tahap pengujian yang bertujuan untuk mengetahui kualitas dari alat yang telah dibuat, mencakup pengujian tegangan dan arus baik input maupun output. Electric Power Converter pada penelitian ini menghasilkan tegangan dengan kisaran antara 0 – 250 VDC dan mempunyai keluaran tegangan dan arus yang stabil.

Kata kunci: Electric Power Converter, Catu Daya, Rancang Bangun, Anodizing.