bluuebunny/crossref_metadata_2025 huggingface dataset:
Interference of personal stigma in occupational performance of adult drug addicts in Portugal: A study at the Unidade de Desabituação do Norte
Authors: Barrantes Francisco , Patrício Joana , Frieza Maria , Custódio Katia , Xavier Celso , Simões Dias Sara
Published: January 2025

Introduction: Given the negative effects of addiction, occupational performance is compromised, impacting on interpersonal relationships and daily routines. Currently there is little literature associating personal stigma with the quality of occupational performance in the drug user population, especially in Portugal. Objective: The aim is to understand how personal stigma can affect the occupational performance of adult individuals with substance dependence, as well as identifying the areas of occupation and activities most affected. Material and Methods: This is a mixed observational and cross-sectional study. Data collection was carried out by applying a sociodemographic questionnaire, the Internalized Stigma of Mental Illness inventory, and a semi structured interview to substance users of the Unidade de Desabituação do Norte. The data analysis and processing were carried out using the WebQDA and SPSS software. Results: The results obtained made possible a better understanding of the areas of occupation and respective activities that are most affected by personal stigma in each sociodemographic variable of the sample, alongside the current literature. The ISMI scale has a Cronbach’s alfa of 0,89, conferring reliability to it, with the sample having a means of 2,42, being the “moderate” level of personal stigma the most representative. It was found that personal stigma affects the participation in IADL’s, health management, labor, and social participation. Conclusion: Given the difficulties caused by personal stigma, it is essential to fight stigma for satisfying occupational performance. Nonetheless, it was also observed that many described difficulties in occupational performance are due to the substance abuse
Supplementation of Dragon Fruit Peel Waste (Hylocereus Polyrhizus) in Goat Ration on Digestibility and Fermentability in Vitro
Authors: Anandari Adelya , Susilawat Iin , Tanuwiria Ujang Hidayat
Published: January 2025

This study aims to evaluate the effect of adding dragon fruit peel (Hylocereus polyrhizus) to goat rations on digestibility and fermentability in vitro. Dragon fruit peel is known to contain antioxidants and nutrients that can improve the quality of animal feed. This study used a completely randomized design (CRD) consisting of 5 treatments and 6 replicates with the addition of different dragon fruit peel (R0 or control) rations without the addition of dragon peel, 5%, 10%, 15% and 20%. The observed variables include dry matter digestibility, organic matter digestibility, total volatile fatty acid production, and ammonia (NH3) production. The results of variance analysis (ANOVA) showed that dragon fruit peel supplementation can significantly increase digestibility and fermentability in vitro. The treatment with the addition of 20% dragon fruit peel (R4) showed the highest performance of DMD of 71.55%, OMD of 81.61% and total VFA production of 195.16 mM while in the production of ammonia (NH3) the treatment with the addition of 10% dragon fruit peel (R2) showed the highest performance with the production value of NH3 as 10.14 mM. This study concluded that supplementation of dragon fruit peel in goat rations can increase the digestibility and fermentability of feed in vitro, as well as provide an efficient and environmentally friendly feed alternative.
The Role of BPM Tools in Achieving Digital Transformation
Authors: Somtochukwu Odionsupu Chinekwu , Adepoju Peter Adeyemo , Francis Ikwuanusi Ugochukwu , Azubuike Chima , Kwaghter Sule Aumbur
Published: January 2025

Digital transformation is reshaping the business landscape, necessitating significant changes in how organizations operate and deliver value. This review paper explores the critical role of Business Process Management (BPM) tools in facilitating digital transformation. It examines how BPM tools align organizational processes with digital transformation goals, improve process efficiency through automation, and integrate with emerging technologies such as AI, machine learning, and the Internet of Things. Furthermore, the paper highlights the strategic implications of BPM tools for organizations, including the need for cultural change, enhancement of customer experience, and long-term sustainability. The discussion concludes with analyzing future trends, predicting greater integration with advanced technologies, and a stronger focus on customer-centric BPM. BPM tools will remain essential for driving innovation, operational agility, and continuous improvement in a digital-first business environment.
Tsunamis in the Japan Major: Shifting Tides and Resilience
Authors: Otsuji Emi , Sharp Luke
Published: January 2025

This reflective piece on the Japan Major at the University of Technology Sydney (UTS) marks three decades of the Bachelor of Arts in International Studies (BAIS), now the Bachelor of International Studies (BIS) since 2022. The past 15 years have been especially transformative for the Japan Major, shaped by two significant events: the devastating tsunami on 11 March 2011 and the declaration of a global pandemic on 11 March 2020. Remarkably connected by a single date, these events frame a reflection on resilience, adaptability, and the evolving practices of global education, with student experiences at the forefront. Using the word ‘tsunami’ both literally and metaphorically, this essay explores how such shifts challenge and inspire pedagogical approaches.
The Southeast Asia Major within the Bachelor of Arts in International Studies at UTS 1996–2007
Authors: Leigh Barbara
Published: January 2025

Between 1996 and 2007, the Bachelor of Arts in International Studies (BAIS) at the University of Technology Sydney offered students the opportunity to engage in transformative In-Country Study (ICS) experiences in Southeast Asia. These transformative experiences broadened students’ intellectual horizons, fostered meaningful connections, and inspired successful careers in fields such as diplomacy, journalism, and academia. These are my reflections as the coordinator of the program.
El Estallido Social and ICS Chile 2019
Authors: Wyndham Marivic
Published: January 2025

This reflection recounts the extraordinary experiences of the 2019 In-Country Study (ICS) Chile cohort during Chile’s Estallido Social, a period of intense social and political unrest. Despite facing immense challenges, including civil unrest and disruptions to their studies, the students demonstrated resilience, adaptability, and a deep commitment to their host communities. Through their collective efforts and independent explorations of Chilean society, they exemplified the global citizenship and intercultural skills nurtured in the International Studies program.
The Global Classroom: ‘We are the Dreamers of Dreams’
Authors: Goodman David S. G.
Published: January 2025

This reflection explores my experiences with the University of Technology Sydney’s (UTS) International Studies program, emphasising the transformative power of The Global Classroom initiative. By integrating language learning, cultural immersion, and overseas study, the program provided students with life-changing opportunities that fostered adaptability, cultural understanding, and global citizenship. My own journey—from shaping the program’s early years to working abroad—reinforced the importance of international education, both for students and educators.
The Red Frock
Authors: Vanni Ilaria
Published: January 2025

In this reflection, I recount my experience supervising a UTS student in Milan during her In-Country Study, where I became a luxury fashion faux buyer as part of her research on luxury shopping. An unexpected encounter in a high-fashion boutique taught me the importance of attentive observation and developing tools to help students make sense of complex global and local interactions. This moment reinforced my appreciation for elevating experiences in teaching and the value of speculative thinking in understanding the interconnectedness of global capitalism, culture, and place.
La vita notturna a Bologna attraverso l’analisi degli statuti (secoli XIII-XV)
Authors: Galletti Filippo
Published: January 2025

Il contributo intende investigare la vita notturna di Bologna (Italia) nel periodo bassomedievale. Attraverso l’analisi delle fonti statutarie redatte tra il XIII e il XV secolo, vengono descritti il ruolo degli ufficiali impiegati nel controllo notturno, il disciplinamento attraverso norme preventive e di divieto, e le attività permesse dalle autorità. I risultati ottenuti permettono di evidenziare un passaggio da una supervisione locale della notte a una esercitata da magistrature forestiere che disciplinano con sempre maggior attenzione anche la sfera morale. Allo stesso tempo, la vita notturna bolognese si caratterizza per una certa dinamicità per via delle molte attività che si svolgevano al calar del sole.
Historia soterrada. La represión franquista en los libros escolares de Bachillerato
Authors: De la Cruz Redondo Alba , Jaén Milla Santiago , Cruz Artacho Salvador
Published: January 2025

La represión franquista es una de las asignaturas pendientes en los libros de texto escolares. Para valorar este tema se han estudiado y analizado los libros de historia de 2º de bachillerato en Andalucía. Se elaboró una ficha de recogida de información que, posteriormente, fue aplicada a las unidades didácticas que abordan la Guerra Civil, la dictadura franquista y la actual democracia en los manuales seleccionados. Se encuentra que ninguna editorial resuelve correctamente la inclusión de esta cuestión en sus manuales, habiéndose advertido numerosas deficiencias en el abordaje de la represión franquista. Se plantean ideas y propuestas para incluirla, de forma real.
Profitability and Efficiency of Cassava Production in Ekiti State, Nigeria
Authors:   Department of Agricultural and Resource Economics, Federal University of Technology, P.M.B. 704, Akure, Nigeria., Bello Temitope Olanrewaju , Oguntade Adegboyega Eyitayo ,   Department of Agricultural and Resource Economics, Federal University of Technology, P.M.B. 704, Akure, Nigeria., Afolayan Thomas Tope ,   Department of Agricultural and Resource Economics, Federal University of Technology, P.M.B. 704, Akure, Nigeria.
Published: January 2025

This research examines the profitability and efficiency of cassava farming in Ekiti State, Nigeria, with a focus on evaluating the economic viability and production efficiency of this vital crop within smallholder farming systems. Cassava plays a crucial role in enhancing food security and generating rural incomes in Nigeria. The study adopts a comprehensive research approach, incorporating structured surveys and interviews with cassava farmers from selected communities in Ekiti State. To ensure a representative sample, a multi-stage sampling technique was applied. Data were gathered using a structured questionnaire, which captured information on socio-economic characteristics, cassava farming inputs and outputs, input costs, and tuber prices. Analytical methods included descriptive statistics, Gross Margin Analysis, and the Stochastic Frontier Production Model. Results highlight diverse profitability levels among cassava farmers and identify factors contributing to production inefficiencies. Strategies to enhance market access and patronage for cassava products were also explored. In Ekiti State, smallholder farmers typically realize ₦4.28 for every ₦1 invested in cassava production, with an observed increase of 1 kg in yield per 1-liter increase in agro-chemical use. Experienced farmers demonstrate higher technical efficiency, while average farmers could achieve up to a 7.5% increase in cost savings or production output by reaching the allocative efficiency levels of their most efficient counterparts. Poor patronage emerged as a critical constraint. Key recommendations include implementing targeted training programs to enhance the technical and allocative efficiency of less experienced farmers. Additionally, strategies should focus on improving market access and increasing patronage for cassava products to maximize profitability and efficiency in cassava farming within Ekiti State.
Etika Berinformasi dalam Al-Qur’an
Authors: Setiawan Ahmad Bayu
Published: January 2025

The main reason for the failure of the praxis ideal democratic conception is the absence of a critical society and has the ability to control and maintain objectivity, freedom, and openness of information in the mass media. This is in praxis, indeed democracy turns out to run contrary to the concept of ideal democracy with the mastery of the mass media. Thus, there is an assumption that ordinary people are not capable enough to be well informed. From this research based on Islam and the Quran, it reveals that in realizing an ideal democratic society, a good ability to inform is needed. The Quran in some places has hinted at instructions for mankind, especially Moslem, about the value and ethics of information as in Q.S an-Nisa' verse 83 and al-Hujurat verse 6. By exploring the interpretation of both verses, the author discovers some values and ethics that must be considered in information. The application of these values and ethics will then form a society that is critical in information which then has implications for the formation of a healthy mass media and realizing ideal democratic praxis.
Arsitektur Alif dan Alef
Authors: Ulil Abshor Ulil Abshor
Published: January 2025

The letters Alif and Alef are architectural masterpieces. Architecture is not only constructed to meet basic human needs. In a semiotic perspective, architecture is a text and is designed to be rich in philosophical values, so it is necessary to trace the meanings contained in it. This research is a literature, with a comparative inductive method. The approach is semiotic architecture. As a result, the Alif and Alef architectures are designed to be timeless so that the letter values can become a guideline that is firmly held by their users. Its extra-detailed design shows the sacredness of the letter. Apart from being the name of God, the letter is constructed as an icon of tahlil or tehlel monotheism that interprets the oneness of God and there is no God but Him. He is All Supreme and to Him man must submit, serve and hold on to His words. Its abstract qualities are the image of infinity and something indescribable.  His intentions show that God is the Creator, can only be articulated through the wonders of His creations. The numerical value of one represents a beginning and the only path to be walked. One thousand is an infinity number that means everything comes from the One Dzat no one can feel high because God is Al-Mutakabbir. And among the ways of obtaining sprirituality is to neutralize lust.
Radyasyon Fiziği
Authors:   İstanbul Üniversitesi-Cerrahpaşa, Cerrahpaşa Tıp Fakültesi, Nükleer Tıp Ana Bilim Dalı, İstanbul, Türkiye, Demir Mustafa
Published: January 2025

Nükleer tıp multidisipliner bir bilim dalı olup, açık radyasyon kaynaklarının tıpta tanı ve tedavi
amacıyla kullanım alanı olarak tanımlanabilir. Radyasyonun 1896’da Henry Becquerel tarafından keşfedilmesinden günümüze kadar geçen süre içinde giderek yaygınlaşan kullanım alanları
olmuştur. Radyoaktif maddelerin üretimi, tıbbi amaçla kullanımı ve radyoaktif maddelerin biyolojik zararlarının bilinmesi radyasyon korunmasını da gündeme getirmiştir. Uluslararası Radyasyon Korunması Komitesinin (ICRP) kuruluş yılları 1925’e kadar uzanmaktadır. Günümüzde
ulusal ve uluslararası komiteler işlevsel durumda olup belirli aralıklarla korunma kurallarını
belirten tavsiye kararları yayınlamaktadır. Bu kitabın içeriğinde ICRP tavsiye kararlarına yer
yerildi. Bu bölümde, ağırlıklı olarak Nükleer Tıp özelinde Radyasyon Fiziği konuları işlendi.
Radyoaktif kaynağa ait bilgilerin işlendiği temel nükleer tıp fiziği konuları, radyasyonun doğası,
çeşitleri, radyoaktivite birimleri, röntgen fiziği, X-ışınlarının özellikleri ve tıbbi amaçlı kullanım
alanları, Ultrasonografi Fiziği, Bilgisayarlı Tomografi Fiziği ve Manyetik Rezonans Fiziği konuları
yer almaktadır.
Otsu Süs Bitkileri
Authors:   İstanbul Üniversitesi-Cerrahpaşa, Ormancılık Meslek Yüksek Okulu, Park ve Bahçe Bitkileri Bölümü, Peyzaj ve Süs Bitkileri Yetiştiriciliği Programı, İstanbul, Türkiye, Yılmaz Hatice
Published: January 2025

Canlı renklere sahip gösterişli çiçekleri, farklı şekil ve büyüklükteki yaprakları ve dikkat çekici
meyveleriyle ilgi ve kontrast sağlayan otsu süs bitkiler, peyzajın vazgeçilmez unsurlarıdır. Ağaçlar
ve çalılar mimari etki yaratırken, nispeten uzun ömürlü çok yıllık otsu bitkiler kalıcı doku, renk
ve form çeşitliliği sağlar. Bir yıllık otsu bitkiler ise tasarımı bir oya gibi işleme ve peyzajda her
yıl değişiklik yapabilme olanağı sunarlar. Bir yıllık ve çok yıllık otsu bitkiler doğru seçimlerle bir
arada kullanılarak küçük alanlarda bile sınırsız renk, şekil, doku seçeneği yaratılabilir.
Kitap, ülkemiz park ve bahçelerinde yaygın olarak kullanılan otsu süs bitkilerinin tanıtımı, üretimi, bakımı, yetişme ortamı özellikleri gibi bazı temel bilgileri içermektedir. Kitap kapsamında,
önce familyaların başlıca özellikleri verilmiştir. Ardından, cins içindeki bitkilerin ayırt edici özellikleri açıklanmış ve bunların kullanım yeri, yetiştirme, çoğaltma ve bakımı hakkında bilgiler
verilmiştir. Türlere özgü yetiştirme ihtiyaçları var ise bunlar ayrıca belirtilmiştir. Son olarak da
yaygın kullanılan türlerin temel özellikleri tanımlanarak teşhisine ve seçimine yardımcı olacak
renkli fotografları verilmiştir.
Uygulamada ve günlük konuşmalarda yerel bitki adları kullanılsa da doğru bitkiyi seçmek ve
temin etmek için bitkilerin bilimsel adını kullanmak gerekir. Bu sebeple kitapta bitkilerin bilimsel ve yerel adları birlikte kullanılmış, fidanlık etiketlerinde ve bahçecilikte halen yaygın şekilde
kullanılan geçersiz (sinonim) isimlere de yer verilmiştir.
Bitkiler tanıtılırken kullanılan terimlerin açıklaması, kitabın sonunda bir terimler sözlüğü halinde verilmiştir. Kitap 260 otsu süs bitkisini içerir. Otsu süs bitkilerinin çeşitliliği göz önüne alındığında çok kapsamlı olmasa da sık kullanılan türleri temsil etmektedir
Hücre Temel Özellikleri
Authors:   İstanbul Üniversitesi-Cerrahpaşa, Cerrahpaşa Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Biyoloji Ana Bilim Dalı, İstanbul, Türkiye, Onaran İlhan , Güven Mehmet ,   İstanbul Üniversitesi-Cerrahpaşa, Cerrahpaşa Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Biyoloji Ana Bilim Dalı, İstanbul, Türkiye
Published: January 2025

Bu bölüm içerisinde hücrenin temel özellikleri ile gram pozitif ve negatif bakteriler çerçevesinde prokaryotik hücreler ile ökaryotik hücreler arasındaki yapısal, organizasyonel ve fonksiyonel
temel benzerlikler ve farklılıkları gözden geçirilecektir. Kitabın bu alt başlığında aynı zamanda
iki hücre alt tipinin farklılıklarının ve benzerliklerinin bilinmesinin ve ortaya çıkartılmasının tıptaki önemi tartışılacaktır.
Canlı ve cansız tüm oluşumların zaman sürecindeki değişimlerini inceleyen evrim teorisine
göre, bu süreçteki ilk basamak evren ve dünyanın oluşumu olup, canlı yaşam formları bu süreçten sonra başlamıştır. Yaşam için gerekli tüm biyolojik olayların gerçekleştiği canlının en küçük
birim olan hücre, prokaryot ve ökaryot olarak ikiye ayrılsa da, her iki hücre tipi de başlangıçta
ortak bir atadan türemiştir. Ortak bir prokaryotik atasal hücrenin evrim sürecinde; Yaklaşık 3,8
milyar yıl önce prokaryotik yaşam başlamış ve bu hücrenin evrimi ile de yaklaşık 2.7 milyar yıl
önce ökaryotik yaşam başlamıştır
Hücre Membran Farklılaşmaları
Authors:   İstanbul Üniversitesi-Cerrahpaşa, Cerrahpaşa Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Biyoloji Ana Bilim Dalı, İstanbul, Türkiye, Bolkent Sema
Published: January 2025

Hücre membranı hücrenin apikal, lateral ve bazal yüzeylerinde fonksiyonlarına göre farklılık
gösterir. Apikal yüzeyde mikrovillus ve sterosilya emilim yüzeyini arttıran membran farklılaşmalarıdır. Hareketli apikal yüzey farklılaşması olan silya ve kamçı plazma membranı ile çevrili
9 adet çift mikrotübül ve merkezde 2 adet tek mikrotübülden oluşur. Hareketli silya (9+2) epitel
hücrelerinde salgıların, yabancı cisimlerin taşınmasında veya sperm kamçı yapısın da spermin
hareketini sağlar. Çeşitli hastalıklar örneğin; kistik böbrek, obezite, zeka geriliği, körlük, çeşitli
gelişim bozuklukları siliopatiler yani silya bozuklukları ile ilişkilidir. Apikal yüzeyin hemen altında bulunan ilk lateral yüzey farklılaşması sıkı bağlantıdır. Beyin kapiler endotel hücre apikalindeki sıkı bağlantı, kan-beyin bariyeri olarak adlandırılır. Menenjit gibi inflamatuvar durumlarda
kan-beyin bariyerinin yapısı bozulur. Kaderin ailesine ait adezyon proteinleri ile iki komşu hücre
birbirine bağlandığında desmozom ve adherens bağlantı oluşur. İntegrin ailesine ait adezyon
proteinleri ile hücreler ekstrasellüler matrikse bağlanarak aktine bağlı hücre matriks adezyonu (fokal adezyon) ve hemidesmozom bağlantılarını oluşturur. Öldürücü olabilen otoimmün
deri hastalığı olan pemfigus’da kişiler kendi desmozomal kaderin proteinlerine karşı antikor
oluşturur. Bazal lamina epitel, kas, yağ ve Schwann hücrelerini çevreleyerek, hücreleri bağ dokudan ayırarak seçici moleküler filtre olarak iş görür. Bazal lamina hücrenin canlılığı, çoğalması, farklılaşması ve göçünü kontrol eder. Bazal lamina proteinlerinde veya keratin tiplerinde
görülen genetik bozukluklar epidermolizis bülloza adı verilen bazen ölümcül olabilen kabarcıklı
deri hastalığına neden olur.
Hücre Yaşlanması
Authors:   İstanbul Üniversitesi-Cerrahpaşa, Cerrahpaşa Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Biyoloji Ana Bilim Dalı, İstanbul, Türkiye, Ulutin Turgut , Öztürk Melek ,   İstanbul Üniversitesi-Cerrahpaşa, Cerrahpaşa Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Biyoloji Ana Bilim Dalı, İstanbul, Türkiye
Published: January 2025

Hücre yaşlanması, DNA hasarı, telomer işlev bozukluğu, onkogen aktivasyonu ve organel stresi
gibi çeşitli faktörlerle tetiklenir. Hücre yaşlanmasının genetik olarak programlanır. Telomerlerin kısalması, hücre bölünmesinin durmasına ve yaşlanmaya yol açar. Serbest radikallerin neden olduğu hasarlar ve DNA’daki hatalar hücre yaşlanmasını tetikler. p53, p16, p21 gibi genler
hücresel yaşlanmada önemli rol oynar. BRAF ve Ras gibi onkogenler hücresel yaşlanmayı tetikleyebilir. Yaşlanmış hücrelerin salgıladığı senesens ilişkili salgı fenotipi (SASP) yaşa bağlı hastalıklarla ilişkilidir. Yaşlanma ile ilişkili ß-galaktosidaz (SA-ß-gal) ve p16 ekspresyonu gibi biyobelirteçler yaşlanmayı tanımlamada kullanılır. Otofaji, hasarlı organelleri ortadan kaldırarak
yaşlanmayı bastırabilir. Sirtuinler ve sestrinler hücresel yaşlanmayı engelleyici etkiler gösterir.
Endoplazmik retikulum (ER) protein ve lipit sentezine katılan hücre içi kanallar sistemidir. Granüllü (GER) ve düz yüzlü (DER) olmak üzere yapı ve işlevsel olarak birbirinden farklı olan iki tip ER vardır. DER özellikle lipid metabolizması ile ilgili hücrelerde daha fazla bulunur. Karaciğer hücrelerinde detoksifikasyonda görev alır. GER’in esas olarak yönlendirilmiş protein sentezinde görev yapar. GER özellikle salgı proteinlerinin, lizozomal enzimlerin ve plazma membranına ait glikoproteinlerin sentezinden sorumludur. Bu sentez mekanizması Sinyal Hipotezi ile açıklanmıştır
Authors:   İstanbul Üniversitesi-Cerrahpaşa, Cerrahpaşa Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Biyoloji Ana Bilim Dalı, İstanbul, Türkiye, Öztürk Melek
Published: January 2025

Endoplazmik retikulum (ER) protein ve lipit sentezine katılan hücre içi kanallar sistemidir. Granüllü (GER) ve düz yüzlü (DER) olmak üzere yapı ve işlevsel olarak birbirinden farklı olan iki tip
ER vardır. DER özellikle lipid metabolizması ile ilgili hücrelerde daha fazla bulunur. Karaciğer
hücrelerinde detoksifikasyonda görev alır. GER’in esas olarak yönlendirilmiş protein sentezinde görev yapar. GER özellikle salgı proteinlerinin, lizozomal enzimlerin ve plazma membranına
ait glikoproteinlerin sentezinden sorumludur. Bu sentez mekanizması Sinyal Hipotezi ile açıklanmıştır
Golgi Kompleksi
Authors:   İstanbul Üniversitesi-Cerrahpaşa, Cerrahpaşa Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Biyoloji Ana Bilim Dalı, İstanbul, Türkiye, Öztürk Melek
Published: January 2025

Golgi kompleksi, hücrede proteinlerin işlenmesi, paketlenmesi ve taşınması süreçlerinde rol
alan oldukça dinamik önemli bir organeldir. GER’de sentezlenen proteinler Golgi kompleksine
cis-Golgi yüzünden alınır, Golgi sisternalarında plazma membran proteinleri, salgı proteinleri
ve lizozomlara ait proteinler işlenir, seçilir ve daha sonra trans-Golgi ağından özel veziküllere
paketlenerek hedeflerine gönderilirler
Sentriol
Authors:   İstanbul Üniversitesi-Cerrahpaşa, Cerrahpaşa Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Biyoloji Ana Bilim Dalı, İstanbul, Türkiye, Tarkan Argüden Yelda
Published: January 2025

Sentrioller, hücrede “mikrotübül organize edici merkez” olarak görev yapan sentrozomları
oluşturan membransız organellerdir. ~250 nm çapında ve ~450-500 nm uzunluğunda silindir
şeklinde yapılardır. İki adet sentriol birbirine dik açı ile konumlanarak sentrozom yapısını meydana getirirler. Sentrozomlar interfazda hücre iskeletini oluşturan mükrotübüllerin oluşumundan sorumluyken, hücre bölünmesi sırasında iğ iplikçiklerinin bipolar mikrotübüllerinin kutuplarını meydana getirirler. Dinlenme halindeki hücrelerde tamamen olgun bir sentriol plazma
membranına yerleşerek silium oluşumunda görev alan bir bazal cisimcik (basal body) haline
dönüşebilir
Tinnitus, Değerlendirmesi ve Yönetimi
Authors:   Akustik Odyoloji Merkezi, Odyoloji Bölümü, İstanbul, Türkiye, Hayır Şenkaya Duygu , Yerlikaya Aysel Bengi ,   İstanbul Üniversitesi-Cerrahpaşa, Cerrahpaşa Tıp Fakültesi, Kulak Burun Boğaz Anabilimdalı, Odyoloji Bölümü, İstanbul, Türkiye
Published: January 2025

Tinnitus, dış uyaran olmadan algılanan ses olarak tanımlanmaktadır ve nüfusun önemli bir kısmını etkileyerek rahatsızlık ve yaşam kalitesinde azalmaya yol açmaktadır. Bu bölüm, tinnitusun
tanımı, tarihi, sınıflandırılması, epidemiyolojisi, mekanizmaları, risk faktörleri ve tanı yöntemlerini ayrıntılı bir şekilde ele almaktadır. Tarihsel bağlam, tinnitus araştırmalarının antik uygarlıklara kadar uzandığını ve uzun süredir devam eden etkisini vurgulamaktadır. Sınıflandırma, tinnitusun subjektif ve objektif türlere ayrılmasını, pulsatile ve etiyolojik özelliklere göre daha fazla
alt gruplandırılmasını içermektedir. Epidemiyolojik veriler, yaş, cinsiyet ve çevresel maruziyet gibi
faktörlere bağlı olarak geniş bir yaygınlık gösterir.
Tinnitus, hem koklear hem de koklear olmayan kökenlerden kaynaklanabilmektedir. Önemli risk
faktörleri arasında işitme kaybı, genetik yatkınlık, yüksek ses maruziyeti ve psikolojik durumlar
bulunmaktadır. Tanı yaklaşımları, detaylı hasta öyküsü, odyolojik değerlendirmeler ve Tinnitus
Engellilik Envanteri ve görsel analog skalalar gibi psikometrik değerlendirmeleri kapsar.
Tinnitusun tedavi ve yönetim stratejileri, bilişsel-davranışçı terapi ve tinnitus yeniden eğitim terapisinden farmakolojik müdahalelere ve akustik terapiye kadar çok yönlüdür. Kesin bir tedavi
bulunmamakla birlikte, bu yaklaşımlar semptomları hafifletmeyi ve hastaların yaşam kalitesini
artırmayı hedefler. Bölüm, kişiselleştirilmiş tedavi planlarının ve tinnitusun altında yatan mekanizmalar ve etkili terapiler üzerine devam eden araştırmaların önemini vurgular
Peningkatan Hasil Belajar pada Materi Operasi Hitung Campuran dan Penaksiran dengan Menggunakan Media Wordwall
Authors: Sinaga Pirmauli , Syamsuyurnita Syamsuyurnita , Siregar Silsia Risqha Revolina
Published: January 2025

Penelitian ini adalah Penelitian Tindakan Kelas. Tujuan dari pelaksanaan PTK ini untuk meningkatkan hasil belajar operasi hitung campuran dan penaksiran dengan penggunaan web wordwall di kelas IV. Penelitian ini menggunakan pendekatan kuantitatif dan kualitatif (mixed method). Penelitian ini dilaksanakan pada semester ganjil, tahun ajaran 2024/2025. Sampel pada penelitian ini adalah seluruh siswa kelas IV SD Negeri 066054 Medan Denai. Populasi yang digunakan berjumlah 22 orang. Teknik pengumpulan data yaitu dengan instrument tes berbentuk pilihan ganda sebanyak 15 soal. Penggunaan web wordwall pada pembelajaran matematika di kelas IV telah efektif dan ketuntas secara klasikal telah tuntas sebesar 100%. Kefektifan tersebut terlihat dari ketuntasan klasikal dan daya serap klasikal berturut-turut pada siklus I sebesar 54% dan 66%. Pada siklus II menunjukkan bahwa ketuntasan klasikal dan daya serap klasikal berturut-turut pada siklus II sebesar 100% dan 78%. Peningkatan hasil belajar darisiklus I dan siklus II telah memberikan suatu Gambaran bagaiamana perubahan dari pemahaman siswa pada operasi hitung campuran dan penaksiran. Persentasi peningkatan hasil belajar siswa pada siklus II sebesar 36%. Hasil belajar pada materi operasi hitung campuran dan penaksiran meningkat dengan menggunakan media wordwall pada siswa SD.
Pengembangan Lembar Kerja Peserta Didik Berbasis Model Pembelajaran Means-Ends Analysis (MEA) pada Materi Sistem Persamaan Linear Dua Variabel
Authors: Dingkol Andini Herlianti , Sulistyaningsih Murni , Kaunang Derel Filandy
Published: January 2025

Penelitian ini dilatarbelakangi oleh masalah yang ditemukan dari berbagai aspek salah satunya penyebab rendahnya kemampuan matematis peserta didik karena kurangnya efektivitas perangkat pembelajaran yang digunakan yaitu Lembar Kerja Peserta Didik (LKPD). Tujuan dari penelitian ini untuk menghasilkan produk Lembar Kerja Peserta Didik (LKPD) pada materi Sistem Persamaan Linear Dua Variabel dengan model pembelajaran Means-Ends Analysis (MEA) di kelas VIII  SMP PGRI Insil yang valid, praktis dan efektif. Jenis penelitian ini adalah Research and Development (R&D) dengan menggunakan model pengembangan ADDIE (Analysis, Design, Development, Implementation and Evaluation). Skor penilaian dari hasil penilaian validator ahli adalah 87 dengan kategori sangat valid. Untuk skor  penilaian kepraktisan dilihat dari respon siswa dengan skor 92 dengan kategori sangat praktis. LKPD yang dikembangkan ini telah memenuhi kriteria efektif berdasarkan presentase ketuntasan belajar klasikal sebesar 82%. Kesimpulannya, LKPD yang dikembangkan valid, praktis dan efektif untuk digunakan dalam pembelajaran Matematika materi SPLDV.
Profil Pemecahan Masalah Etnomatematiak pada Masalah Geometri Ditinjau dari Keceerdasan Visual Spasial
Authors: Prasetyowati Dina , Kartinah Kartinah , Damayani Aries Tika , Wakhyudin Husni
Published: January 2025

Penelitian ini bertujuan untuk mengetahui bagaimana pendekatan etnomatematika membantu peserta didik menyelesaikan masalah geometri berdasarkan kecerdasan visual spasial. Penelitian ini bertujuan untuk mempelajari kecerdasan visual spasial pada siswa tingkat rendah. Ini adalah jenis penelitian deskriptif kualitatif.  Subyek yang dipilih dalam penelitian ini adalah satu subyek memiliki kecerdasan visual spasial rendah berdasarkan hasil tes yang dilakukan. Kami menggunakan tes kecerdasan spasial, tes pemecahan masalah etnomatematika, dan wawancara. Keabsahan data diperiksa dengan cara menggunakan triangulasi teknik, yaitu dengan memeriksa data dari sumber yang sama namun dengan teknik yang berbeda. Analisis dibuat berdasarkan faktor-faktor kemampuan menyelesaikan masalah dengan mempertimbangkan kecerdasan visual spasial. Penelitian menunjukkan bahwa subyek dengan kecerdasan visual spasial rendah dapat memahami masalah, membuat rencana solusi, dan mencoba memecahkan masalah tetapi tidak sepenuhnya berhasil dan mengalami kesulitan
Эстетическое содержание понятия «рациональность» в контексте теории коммуникативного действия Ю. Хабермаса
Authors: Ибрагимова Мехин
Published: January 2025

В статье рассматривается эстетическое содержание концепта «рациональности в контексте теории коммуникативного действия Ю. Хабермаса. Анализ проводится, исходя из модусов рациональности, заданных и идентифицированных в соответствующих трудах Ю. Хабермаса. В качестве релевантного контекста привлечены также концепции целерациональности и ценностной рациональности. Проблема рациональности рассматривается и с точки зрения процессов социокультурной самоидентификации и смыслообразования.
Assessment of Selected Aspects of Safety Management In The Organization of Mass Events: A Case Study of a Football Club in Poland
Authors: EWERTOWSKI Tomasz , KROLL Nina , FENSTER Jakub
Published: January 2025

This article was motivated by the need to address the knowledge gap identified in the literature analysis. The purpose of this article is to present an assessment of the safety of spectators attending a football match held at the stadium of one of Poland’s sports clubs. The analysis focused on three selected aspects of safety management: security provided by information and security services, medical safety, and the safety of the venue and its infrastructure. Additionally, a fourth aspect—spectators’ sense of safety—was included in the analysis. The study was preceded by a review of literature on the subject matter. The research tools used included a semi-structured interview, observation, an internal audit based on a prepared checklist, and a questionnaire survey. The combination of these research methods allowed for the use of triangulation to enhance the reliability of the study. Furthermore, a custom five-point rating scale was developed, which was used to assess both the overall level of safety at the mass event and management of its individual aspects. Based on the results, it was determined that the overall safety management level at the analyzed stadium ranged between 4 and 5, which corresponds to a range between acceptable and broadly acceptable risk. However, it is important to note the existence of a ‘bottleneck’ in this assessment, represented by the aspect of spectators’ sense of safety, which received an average rating of 3.43, indicating tolerable risk. Several possible improvements have been proposed to enhance safety levels in this particular area.
Analysis of Selected Aspects of a Local Community Safety: A Quantitative and Qualitative Research in A District of Poznan, Poland
Authors: EWERTOWSKI Tomasz , KROLL Nina
Published: January 2025

The aim of this article is to diagnose the state of safety and the sense of safety in the local community of a selected district of Poznan, and to present proposals for changes and improvements based on the identified issues, which will enhance the level of safety and its perception among the local community. Three selected aspects of community safety were analyzed: the effectiveness of public services, the effectiveness of interactive reporting systems, and the local community's sense of safety. To analyze the selected aspects, original research was conducted. The chosen research tools included a survey based on a personal questionnaire, observation, and in-depth interviews. The results of the research provided insights into specific safety-related issues. Subsequently, the topics related to the selected aspects were assessed. A custom five-point rating scale for community safety effectiveness was developed and used for this purpose. In the final part of the paper, a summary was prepared, and conclusions were drawn. The main findings indicate a relatively low assessment of the safety conditions in the analyzed district and the existence of a gap between the actual state of safety and the perceived safety in the local community. This suggests that residents assess the situation more critically than it actually is – due to a small difference of 3.5/3, we can describe this as a state of mild safety obsession. Based on these conclusions, several changes were proposed to improve safety in the selected aspects.
Two Approaches to Ranking Aggregation in The Methodology of Multiple-Level, Multiple Criteria Evaluation of Urban Transportation Projects
Authors: KRUSZYNSKI Miroslaw
Published: January 2025

Purpose: The objective of the study was to propose an alternative approach to aggregating rankings in a multi-level, multi-criteria methodology for assessing urban transport projects (UTP).

A gap in the literature: In the literature, only one approach (so-called horizontal) is presented for aggregating rankings in a multi-level, multi-criteria methodology for assessing UTPs, implemented at two levels: operational (level II) based on the normalization formula for aggregating the substantive utility – local (in a given class) of individual UTPs of an appropriate nature to the substantive utility – global of all UTPs in the entire population, and a global assessment of UTPs, leading to obtaining the final ranking of all projects (level V) based on the aggregation formula for hierarchizing UTPs according to their global utility.

Methodology/Approach used in the study: The study used the multi-level, multi-criteria methodology for assessing UTPs, including the horizontal approach to aggregating rankings; the multi-criteria decision support (MCDS) methodology, the AHP method, which is used to conduct computational experiments; and Spearman’s rank correlation coefficient used to evaluate the vertical approach.

Summary of findings: This article develops and presents a new approach to aggregating rankings in the multi-level, multi-criteria UTP evaluation methodology. This approach aggregates rankings only at one, level V of the methodology and is based: firstly on the original aggregation formula for prioritizing UTPs according to their global utilities obtained within predefined project classes based on their partial utilities (substantive, sectoral, strategic); and secondly on the original formula for normalizing the aggregation of global UTP utilities from predefined classes to prioritize UTPs in the final ranking according to their global utilities of all UTPs in the entire population (irrespective of the project class they were in). This article also evaluates the proposed vertical approach to aggregating rankings in the multi-level, multi-criteria UTP evaluation methodology.
Development of Socially Responsible Organizations and Social Entrepreneurship: Understanding the Framework of Operations in The European Union
Authors: BILAS Vlatka , FRANC Sanja , PUCEK Matija
Published: January 2025

By integrating business practices with social mission goals, social entrepreneurship has emerged as a significant approach to addressing societal challenges and generating lasting benefits for communities. This paper explores the operational frameworks and historical evolution of socially conscious enterprises, with a focus on their development within the European Union. While the concept of social responsibility can be traced back to early charitable and community-focused efforts, such as medieval guilds and nonprofit organizations addressing local economic security, these approaches have evolved into institutionalized models that merge business operations with a primary emphasis on social impact and community welfare. Addressing a gap in the literature, this study provides a detailed examination of how policy developments, legal frameworks, and strategic initiatives in the European Union have shaped the growth of social entrepreneurship, promoting inclusive and sustainable economic progress. Methodologically, the paper combines historical analysis with a review of contemporary institutional practices to differentiate between the concepts of social entrepreneurship and social enterprise. The findings underscore the critical role of social enterprises in addressing gaps left by traditional market and public sector approaches, leveraging innovation and community-centred strategies to tackle pressing societal needs. The paper concludes by identifying challenges and potential areas for further development of the strategic and legal framework for social enterprises in the European Union.
IMPLEMENTASI TASJI’UL LUGHOH AL AROBIYAH : STUDI DIPONDOK PESANTREN PEMBANGUNAN BUSTANUL ULUM JAYASAKTI
Authors: AMRULLAH SYARIF , MAULIDIN SYARIF
Published: January 2025

The Tasyjiul Lughoh Al Arobiyah program at Pondok Pesantren Pembangunan Bustanul Ulum Jayasakti aims to improve the Arabic speaking skills of students through the integration of daily habits in learning. The background of this research is the suboptimal Arabic proficiency of students despite various innovations already implemented. The focus of this study is to explore the effectiveness of a program that emphasizes routine speaking practice, the use of the Daily Conversation book, and weekly evaluations in enhancing Arabic language skills. The research employed a descriptive qualitative method, utilizing direct observation, interviews with teachers and students, and document analysis of program activities. The results show that this program successfully increased students' confidence, speaking skills, and their use of Arabic in daily life. The weekly evaluations also positively impacted their public speaking abilities. The conclusion of this study is that an approach based on daily habits and practical communication is more effective in overcoming difficulties in learning Arabic compared to conventional teaching methods. Prospects for the development of this program include extending the practice time and applying it in other pesantren to improve Arabic learning quality more widely.
ABSTRAKProgram Tasyjiul Lughoh Al Arobiyah di Pondok Pesantren Pembangunan Bustanul Ulum Jayasakti bertujuan untuk meningkatkan kemampuan berbicara bahasa Arab santri melalui integrasi kebiasaan harian dalam pembelajaran. Latar belakang penelitian ini adalah kurang maksimalnya kemampuan berbahasa Arab santri meskipun berbagai inovasi telah diterapkan. Fokus penelitian ini adalah untuk mengeksplorasi efektivitas program yang mengutamakan latihan berbicara rutin, penggunaan kitab Daily Conversation, serta evaluasi mingguan dalam meningkatkan keterampilan berbahasa Arab. Metode yang digunakan adalah deskriptif kualitatif dengan observasi langsung, wawancara dengan guru dan santri, serta analisis dokumen kegiatan. Hasil penelitian menunjukkan bahwa program ini berhasil meningkatkan rasa percaya diri, keterampilan berbicara, dan penggunaan bahasa Arab dalam kehidupan sehari-hari santri. Evaluasi mingguan juga memberikan dampak positif terhadap perkembangan kemampuan berbicara di depan umum. Kesimpulan dari penelitian ini adalah bahwa pendekatan berbasis kebiasaan harian dan komunikasi praktis lebih efektif dalam mengatasi kesulitan belajar bahasa Arab dibandingkan dengan metode pembelajaran konvensional. Prospek pengembangan program ini termasuk perpanjangan waktu latihan dan penerapan di pesantren lain untuk meningkatkan kualitas pembelajaran bahasa Arab secara lebih luas.
THE INFLUENCE OF COMMUNICATION AND WORK ENVIRONMENT ON EMPLOYEE PERFORMANCE AT SMA NEGERI 1 TUMPANG, MALANG DISTRICT
Authors: Anfi Dieva Zahrohtu , Wahyudi Eko Juni , Sudarjo  , Pratesa Dimas Putri Mega , Adelia
Published: January 2025

Penelitian ini bertujuan untuk menganalisis pengaruh komunikasi dan lingkungan kerja terhadap kinerja pegawai di SMA Negeri 1 Tumpang Kabupaten Malang. Kinerja pegawai merupakan faktor penting dalam menunjang kualitas pendidikan, dan salah satu aspek yang dapat mempengaruhi kinerja tersebut adalah komunikasi yang efektif serta lingkungan kerja yang kondusif. Penelitian ini menggunakan pendekatan kuantitatif dengan metode survei, dimana data dikumpulkan melalui penyebaran kuesioner kepada 80 pegawai di sekolah tersebut. Hasil penelitian menunjukkan bahwa komunikasi yang baik dapat meningkatkan kinerja pegawai secara signifikan, sementara itu lingkungan kerja yang nyaman dan mendukung juga memiliki pengaruh positif terhadap kinerja pegawai. Secara keseluruhan, kedua faktor ini terbukti saling berinteraksi dan berkontribusi dalam meningkatkan kinerja pegawai di SMA Negeri 1 Tumpang. Penelitian ini memberikan rekomendasi bagi manajemen sekolah untuk memperbaiki kualitas komunikasi internal serta menciptakan lingkungan kerja yang lebih mendukung guna meningkatkan kinerja pegawai.
PENGARUH CURRENT RATIO (CR), DEBT TO EQUITY RATIO (DER), DAN NET PROFIT MARGIN (NPM) TERHADAP HARGA SAHAM DENGAN PRICE BOOK VALUE (PBV) SEBAGAI VARIABEL MODERASI (STUDI PADA PERUSAHAAN SEKTOR FNERGI YANG TERDAFTAR PADA INDEKS LQ-45 TAHUN 2018-2022.)
Authors: Fatimah  , Setyawati Amelia , Sholichah Fatmawati
Published: January 2025

Dampak   yang   diakibatkan   perang   Rusia-Ukraina   terhadap   komoditas   energi   tersebut   juga berkemungkinan  memberikan  pengaruh  pada  pasar  modal  di  Indonesia. Faktor-faktor seperti likuiditas perusahaan, profitabilitas perusahaan, solvabilitas perusahaan dapat berpengaruh harga saham yang ditetapkan pasar modal. Ketiga faktor ini sangat penting dalam menentukan kinerja keuangan perusahaan dan dapat menjadi faktor tinggi rendahnya harga saham dari entitas tersebut (Aji and Ac, 2024). Penelitian ini bertujuan (1) Untuk mengetahui dan menganalisis pengaruh singnifikan Current Ratio (CR),  Debt to Equity Ratio (DER), Net Profit Margin (NPM) secara parsial terhadap harga saham pada perusahaan sektor energi yang terdaftar pada  Indeks LQ-45 Periode 2018-2022    (2) Untuk mengetahui dan menganalisis kemampuan Price to Book Value (PBV) memoderasi pengaruh Current Ratio (CR), Debt to Equity (DER), Net Profit Margin (NPM) terhadap harga saham pada perusahaan sektor energi yang terdaftar pada  Indeks LQ-45 Periode 2018-2022. Jenis penelitian ini adalah kuantitatif, dengan populasi dan sampel adalah perusahaan sektor energi yang terdaftar dalam Indeks LQ 45 periode 2018-2022, berjumlah 8 perusahaan.
Hasil penelitian menunjukkan bahwa Current Ratio (CR) berpengaruh tidak signifikan secara parsial terhadap harga saham pada perusahaan sektor energi yang terdaftar dalam Indeks LQ45 periode 2018-2022, Debt to Equity Ratio (DER) berpengaruh signifikan secara parsial terhadap harga saham pada perusahaan sektor energi yang terdaftar dalam Indeks LQ45 periode 2018-2022, Net Profit Margin (NPM) berpengaruh tidak signifikan secara parsial terhadap harga saham pada perusahaan sektor energi yang terdaftar dalam Indeks LQ45 periode 2018-2022. Price to Book Value (PBV) tidak memoderasi pengaruh Current Ratio (CR) terhadap harga saham pada perusahaan sektor energi yang terdaftar pada indeks LQ45 periode 2018-2022, Price to Book Value (PBV) tidak memoderasi pengaruh Debt to Equity Ratio (DER) terhadap harga saham pada perusahaan sektor energi yang terdaftar pada indeks LQ45 periode 2018-2022. Dan Price to Book Value (PBV) tidak memoderasi pengaruh Net Profit Margin (NPM) terhadap harga saham pada perusahaan sektor energi yang terdaftar pada indeks LQ45 periode 2018-2022.
ANALISIS GREEN TOURISM DI THAILAND: MENUJU PARIWISATA BERKELANJUTAN DALAM PERSPEKTIF EKONOMI DAN SUMBER DAYA MANUSIA
Authors: Saifuddin  , Sugangga Rayyan , Iradah Rahman  , Syarifah Mahdiyah
Published: January 2025

Thailand leads Southeast Asia in terms of foreign tourist arrivals. However, the rapid growth of the tourism industry often has adverse consequences for the environment. Contemporary tourism management has to deal with major issues such as pollution, habitat degradation, and overcapacity of tourist destinations. Therefore, the term “green tourism”, also known as “green tourism”, has emerged as an alternative to achieve a balance between environmental preservation and tourism industry development. The purpose of this article is to identify the concept and implementation of green tourism in Thailand as an effort towards sustainable tourism by reviewing its impact from an economic and human resources (HR) perspective. The article is written using a qualitative descriptive method approach with a literature study to describe in detail and in depth a certain phenomenon based on data and information obtained from various literature sources. The discussion of this article found that the role of education in encouraging pro-environmental behavior is also an important concern. Studies in Thailand show that additional years of formal education increase the likelihood of individuals to take knowledge-based environmentally friendly actions, such as the use of energy-saving tools, as well as appearing that majority religious principles or values have an impact on the implementation of Green Tourism in Thailand