bluuebunny/crossref_metadata_2025 huggingface dataset:
Eksistensi Surau di Era Modernisasi: Daya Tahan dan Perubahan Surau Buya Lubuak Landua di Pasaman Barat
Authors: Khoiroti Miftahul
Published: January 2021

This research examines the resilience and change of Surau Buya Lubuak Landua in the West Pasaman region, which is 167 years old in the midst of modernization. Although in his journey Surau Buya Lubuak Landua has experienced a crisis due to ideas of religious reform in all its aspects which caused the surau to experience shock, nevertheless Surau Buya Lubuak Landua has survived until now. This research uses a qualitative-descriptive method. This method tries to explain all events, incidents related to Surau Buya Lubuak Landau in detail according to current conditions. The results showed that the existence of Surau Buya Lubuak Landua had a very significant development, with an estimated age that was as old as Islam in the West Pasaman region. During its development, Surau was more focused on teaching religious education. The development and durability of the Buya Lubuak Landua surau was possible because of the comprehensive cooperation between Buya Lubuak Landua, the government, traditional leaders, and the community in maintaining the sustainability of the surau. In addition, Buya Lubuak Landua's ability to streamline the elements of surau to function properly can help mobilize the economic potential of the Lubuak Landua community.
Penelitian ini mengkaji daya tahan dan perubahan Surau Buya Lubuak Landua di wilayah Pasaman Barat yang telah berusia 167 tahun di tengah arus modernisasi. Meskipun dalam perjalanannya Surau Buya Lubuak Landua pernah mengalami krisis akibat adanya ide-ide pembaharuan keagamaan dalam segenap aspeknya yang menyebabkan surau mengalami goncangan, namun demikian Surau Buya Lubuak Landua tetap bertahan hingga saat ini. Penelitian ini menggunakan metode kualitatif-deskriptif. Metode ini berusaha menjelaskan segala peristiwa, kejadian yang berhubungan dengan Surau Buya Lubuak Landau secara terperinci sesuai dengan kondisi sekarang. Hasil penelitian menunjukkan bahwa eksistensi Surau Buya Lubuak Landua mengalami perkembangan yang sangat signifikan, dengan capaian usia yang diperkirakan setua usia Islam di wilayah Pasaman Barat. Dalam perkembangannya, surau lebih terfokus pada pengajaran pendidikan agama.   Perkembangan dan daya tahan surau Buya Lubuak Landua dapat terlaksana karena adanya kerjasama yang komprehensif antara Buya Lubuak Landua, pemerintah, pemuka adat, dan masyarakat dalam menjaga keberlangsungan surau. Selain itu kemampuan Buya Lubuak Landua dalam mengefektifkan unsur-unsur surau agar berfungsi dengan baik dapat membantu dalam menggerakkan potensi ekonomi masyarakat Lubuak Landua.
Moderasi Islam Pespektif Sufi: Kajian Kitab Tajul ‘Arus Karya al-Syaikh Tajuddin Ibn ‘Athaillah al-Sakandari
Authors: Dahri Harapandi
Published: January 2021

Islam as one of the divine religions carries the message of peace, harmony between people and even between God's creatures (rahmatan lil 'Ālamîn). There is no single text either al-Qur'an or al-Hadith which instructs its adherents to do the opposite, think and act radically and are anti-establishment. This problem by the previous scholars has been explained in various strokes of their thoughta. This article focuses on the thoughts of al-Shaykh Tajuddin ibn 'Athaillah al-Sakandari as one of the classical Sufism scholars who concentrate on and focus on the harmonization and moderation of Islam. By using a text and context study approach to the Kitab Tâjul 'Arus, this article finds that Islamic moderation in the Sufi perspective is seen through concepts such as al-taubah, the nature of ittibâ' al-Nabi, ahwâl al-qalb wa al-nafs, asrâr. al-Salah, as well as a lover of the world and the hereafter. Therefore, moderation in Islam is the highest value that must be maintained and carried out by every human being, so that there are no words of swearing, insults, or persecution in the name of religion, race, and group. Faith in Allah and love for the Messenger of Allah should be able to be a force in stopping all forms of injustice against everyone, even other creatures of God.

Islam sebagai salah satu agama samawi membawa pesan perdamaian, keharmonian antara sesama bahkan antara makhluk Allah (rahmatan lil ‘Ālamîn). Tiada satu teks baik al-Qur’an maupun al-Hadits yang menyuruh penganutnya melakukan perkara-perkara sebaliknya, berfikir dan bertindak radikal dan anti kemapanan. Persoalan tersebut oleh para ulama’ terdahulu telah dijelaskan dalam berbagai goresan pemikirannya. Artikel ini fokus pada pemikiran al-Syaikh Tajuddin ibn ‘Athaillah al-Sakandari sebagai salah satu dari ulama tasawuf klasik yang konsen dan fokus terhadap harmonisasi dan moderasi Islam. Dengan menggunakan pendekatan kajian teks dan konteks atas Kitab Tâjul ‘Arus, artikel ini menemukan bahwa pemikiran moderasi Islam dalam perspektif sufi terlihat melalui konsep-konsep seperti al-taubah, hakikat ittibâ’ al-Nabi, ahwâl al-qalb wa al-nafs, asrâr al-Shalah, serta pencinta dunia dan akhirat. Karenanya, moderasi dalam Islam adalah nilai (value) tertinggi yang mesti dijaga dan dijalankan oleh setiap insan, sehingga tiada terdengar kata-kata umpatan, cacian, maupun persekusi atas nama agama, ras, dan juga golongan. Keyakinan akan Allah dan kecintaan kepada Rasulullah mestinya dapat menjadi kekuatan dalam memberhentikan segala bentuk ketidakadilan terhadap setiap insan bahkan pada makhluk-makhluk Tuhan yang lain.
Pembentukan Identitas Sosial Perempuan pada Zaman Orde Baru dalam Novel Saman Karya Ayu Utami
Authors: Nuri Zalifa , Machdalena Susi
Published: January 2021

This paper discusses the formation of women's identity in the novel Saman. Lately, women's social identity has changed in meaning with the times, so the author wants to analyze the identity of women in this novel. This novel has a background in the New Order era, the author wants to analyze how the formation of women's identity at that time. This paperis a qualitative approach with descriptive study by the writer reading the novel. The author uses Henri Tajfel's Theory of identity which explains that social identity is part of the concept of each individual who comes from his membership and is in a social group where the social group has the same values and emotional significance in the membership. The results of the analysis show that there is a strong influence from the socialization stage of parents to children because parents are the first and foremost people who carry out social interactions with children. In addition, in the novel, during the New Order era, there was a state policy towards women or mothers/parents with the five dharma program so that it had an influence on the formation of women's identity, besides that the influence of the environment and policies in the New Order era had a strong influence on the formation of women's identity.

Tulisan ini membahas tentang pembentukan identitas perempuan dalam novel Saman. Akhir akhir ini identitas sosial perempuan menjadi berubah arti seiring berkembangnya zaman, oleh sebab itu penulis ingin menganalisis tentang identitas perempuan pada novel ini. Novel ini berlatar belakang waktu pada zaman orde baru, penulis ingin menganalisis bagaimana pembentukan identitas perempuan pada zaman itu. Tulisan ini merupakan penelitian kualitatif dengan studi deskriptif dengan cara penulis membaca novel tersebut. Penulis menggunakan Teori identitas Henri Tajfel menjelaskan terkait identitas sosial yaitu sebagai sebuah konsep pada setiap individu yang asal muasalnya dari keanggotaan komunitas dan berada dalam komunitas sosial tersebut, komunitas tersebut merupakan kelompok sosial yang memiliki kesamaan nilai serta kesamaan emosional dalam keanggotaan komunitas tersebut. Hasil analisis menunjukkan adanya pengaruh kuat dari tahap sosialisasi orang tua pada anak dikarenakan orang tua adalah orang pertama dan utama yang melakukan interaksi sosial dengan anak. Selain itu, dalam novel itu di masa orde baru ada kebijakan negara terhadap para perempuan atau ibu/orang tua dengan programnya panca dharma sehingga memberikan pengaruh pada pembentukan identitas perempuan, selain itu pengaruh lingkungan dan kebijakan pada zaman orde baru memberi pengaruh kuat dalam pembentukan identitas perempuan.
Reading Indonesian and Malaysian Young Adult Novels: Capturing the Image of Young Muslim Women in Indonesia and Malaysia
Authors: Ismah Nor
Published: January 2021

A number of novel remaja, which mean young adult novels, written by women writers from Indonesia and Malaysia have been published. Writing competitions held by book publishers and language centers have also encouraged the production of the novels. However, since they address youth as their readers and tend to consider the characters, issues, language, and values that appeal to the modern young adult; therefore, some critics say that the novels only respond to the demands of the reader market and they are less creative and lack of quality. In this paper I demonstrate the value of Indonesian and Malaysian novel remaja by examining four novels which are Siti Zaleha M. Hashim’s Biarkan Kupu-Kupu Terbang (“Let the Butterfly Fly”), Rumah Cinta Kelana (“The Love House of Kelana”), written by Sofie Dewayani, Nisah Haron’s Mencari Locus Standi (“Finding the Defense Locus”), and Jadilah Purnamaku Ning written by Khilma Anis. I argue that those novels do not only explore young adults’ feelings, including romance, fear, sadness, happiness, and challenges, but they also describe important themes which may inspire young readers, such as how young Muslim women deal with their identity formation, living in a single mother family, and polygamy.

 

Novel-novel remaja karya penulis perempuan banyak diterbitkan di Indonesia dan Malaysia. Lomba menulis yang diadakan oleh penerbit buku dan pusat bahasa juga mendorong banyaknya produksi novel-novel tersebut. Namun, karena novel remaja menyasar remaja sebagai pembacanya, novel tersebut ditulis dengan mempertimbangkan karakter, isu, bahasa, dan nilai-nilai yang menarik bagi remaja modern. Sehingga, beberapa kritikus mengatakan bahwa novel remaja hanya menjawab tuntutan pasar pembaca dan kurang kreatif serta berkualitas. Tulisan ini bertujuan untuk menunjukkan nilai positif novel remaja yang terbit di Indonesia dan Malaysia dengan menelaah empat novel. Yaitu, Biarkan Kupu-Kupu Terbang karya Siti Zaleha M. Hashim, Rumah Cinta Kelana yang ditulis oleh Sofie Dewayani, Mencari Locus Standi karya Nisah Haron, dan Jadilah Purnamaku Ning ­yang ditulis oleh Khilma Anis. Saya berpendapat bahwa novel-novel tersebut tidak hanya mengeksplorasi perasaan remaja, termasuk percintaan, ketakutan, kesedihan, kebahagiaan, dan tantangan hidup, tetapi juga menggambarkan tema-tema penting yang dapat menginspirasi pembaca remaja. Misalnya, tema tentang bagaimana remaja Muslim perempuan menjalani proses pembentukan jati diri, hidup bersama keluarga dengan ibu tunggal, dan poligami, bahkan juga mengkritisi ketimpangan posisi perempuan di dalam masyarakat.
Analysis of Islamic Messages in the Lyrics of Sawéran Local Wisdom in The Pasirtamiang Communities in Ciamis
Authors: Widiawati Nani , Fitriyani Ela Nurlaela
Published: January 2021

The research is focused on finding the social, geographical, and religious context of the sawéran tradition in the Muslim community of Pasirtamiang, the dynamics of the message narrative in the sawéran lyrics, and the Islamic values and messages contained therein. This focus is important so that the dialectic between religion and culture, which is sometimes seen as a form of syncretism that endangers religion's existence, can be clarified. In this writing, the Muslim community of Pasirtamiang shows a fairly representative model of religious and cultural dialectics so that their people can preserve their cultural heritage without losing their Islamic identity. The research used explanative methods to find causal relationships between local wisdom facts identified by participant observation and in-depth interviews. The results showed that the socio-geographic and religious factors of the Pasirtamiang community also influenced the development process of the sawéran tradition. The format and substance of the sawéran content have transformed, the lyrics are simpler, and the Islamic values are emphasized, both technically and substantially. Islamic values in the lyrics sawéran are classified into divine, spiritual, and moral values. Overall, the content of sawéran's lyrics is an integral part of the Islamic message.

Penelitian difokuskan untuk menemukan konteks sosial, geografis, dan religius tradisi sawéran dalam masyarakat muslim Pasirtamiang, dinamika narasi pesan dalam lirik saweran, serta nilai dan pesan Islam yang terkandung di dalamnya. Fokus ini penting supaya dialektika antara agama dan budaya, yang terkadang ditengarai sebagai bentuk sinkretisme yang membahayakan eksistensi agama, dapat diklarifikasi. Dalam tulisan ini, masyarakat muslim Pasirtamiang menunjukkan model dialektika agama dan budaya yang cukup representatif sehingga masyarakatnya dapat melestarikan warisan budaya tanpa kehilangan identitas keislamannya. Penelitian ini menggunakan metode eksplanatif untuk menemukan hubungan kausalitas antara fakta kearifan lokal yang diidentifikasi melalui observasi partisipan dan wawancara mendalam. Hasil penelitian menunjukkan bahwa faktor sosial-geografis dan keagamaan masyarakat Pasirtamiang turut mempengaruhi proses perkembangan tradisi sawéran. Format dan substansi isi sawéran telah mengalami transformasi, penuturan liriknya lebih sederhana dan semakin menegaskan nilai-nilai keislaman, baik secara teknis maupun substansial. Nilai-nilai Islam dalam lirik sawéran diklasifikasikan menjadi nilai ketuhanan, spiritual, dan moral. Secara keseluruhan, isi lirik sawéran merupakan bagian tak terpisahkan dari pesan Islam.
Syair dalam Pendidikan Islam Madrasah As’ad Jambi Seberang 1944-1970
Authors: Il Yasin Nirwan , Syuhada Siti
Published: January 2021

Researchers and academicians have indeed done a lot of researches in Jambi. The aspects of the life the society of Jambi Seberang in all any studies have been carried out, one of them is historical studies. The research process was also carried out by involving in-depth studies which became a reference to previous studies in this research. The rhyme is one of the Jambi education learning process in the Jambi Seberang area that still needs to be revealed. This awareness also wants to be built in the midst of the many educational patterns that have been adjusted during the times. Rhyme in the 20th century has become a powerful method, in addition to the fact that the people of Jambi have already recognized the repertoire of this rhyme as part of the cultural speech of the people. One of the teachers who uses rhyme in his studies is  teacher Abdul Qodir Ibrahim. This research was using historical methods, namely: Heuristics, criticism, interpretation, and historiography. The disclosure was made so that all forms of educational changes that exist in Jambi society can be appointed as the identity of the Jambi Sebrang society. This disclosure was made in the Jambi Seberang area, which is the first area of Islamic education in Jambi. This investigation tries to explain rhyme in the Islamic education of Jambi community, and the dynamics of its development process.

 Peneliti dan akademisi memang telah banyak melakukan penelitian di Jambi. Aspek sisi kehidupan masyarakat Jambi seberang dalam kajian apapun telah dilakukan. Salah satunya kajian sejarah. Proses penelitian ini pun dilakukan dengan melibatkan kajian yang mendalam yang menjadi referensi tinjauan terdahulu tentang penelitian ini. Syair dalam proses pembelajaran pendidikan Jambi di wilayah seberang Kota Jambi yang masih perlu untuk diungkap. Kesadaran ini juga ingin dibangun di tengah banyak pola pendidikan yang sudah disesuaikan pada perkembangan zamannya. Syair pada akhir abad 20 menjadi metode yang ampuh, disamping memang secara garis besar masyarakat Jambi telah mengenal khasanah syair ini sabagai bagian dari tutur kebudayaan masyarakatnya. Salah satu Tuan guru yang mengunakan syair dalam pembelajarannya yaitu Tuan guru Abdul Qodir Ibrahim. Dalam penelitian ini menggunakan metode ilmu sejarah yaitu: Heuristik, kritik, intepretasi, dan historiografi. Pengungkapan ini dilakukan agar segala bentuk proses perubahan pendidikan yang ada dalam masyarakat Jambi bisa diangkat sebagai identitas masyarakat Jambi. Pengungkapan ini dilakukan di wilayah Jambi Seberang yang merupakan wilayah pertama pendidikan Islam di Jambi. Dalam penelitian ini mencoba menjelaskan syair dalam pendidikan Islam masyarakat Jambi, dan dinamika proses perkembangannya.

 
INTERACTION OF SPATIAL OSCILLATION WITH ROUGHNESS OF SURFACE WORKED BY EXAMPLE OF TURNING
Authors: Schetinin Vladimir , Sablin Pavel
Published: January 2021

The work purpose is to determine the impact of cutter spatial oscillation upon parameters and values of worked surface roughness, in particular, the paper is dedicated to the definition of differences in roughness parameters depending on a projecting plane in which cutter oscillation is considered. There are considered the matters of the impact of cutter spatial oscillation upon roughness of the surface worked, and also cutting parameters influencing the intensity and frequency of oscillation of cutter point oscillation. The solution of the problems specified is carried out on the basis of the analysis of data published in scientific literature and experimental data obtained in the course of investigations. The novelty of the work: it is revealed that a dynamic state of the technological system for machining which depends upon a multitude of factors has an influence not only upon a value of surface roughness, but also upon its parameter. Conclusion: surface roughness depends upon relative oscillation processes of the part under machining and a tool cutting edge in the working space caused mainly by a process of chip formation.
Morphofunctional changes in the colon and immune responses during cold stress in male and female C57BL/6 mice
Authors:   Research Institute of Human Morphology, Moscow, Russia, Zolotova N.A. , Tsvetkov I.S. ,   Research Institute of Human Morphology, Moscow, Russia, Khochanskiy D.N. ,   Research Institute of Human Morphology, Moscow, Russia, Dzhalilova D.Sh. ,   Research Institute of Human Morphology, Moscow, Russia, Kosyreva A.M. ,   Research Institute of Human Morphology, Moscow, Russia, Mikhailova A.L. ,   Lomonosov Moscow State University, Moscow, Russia, Mikhailova L.P. ,   Research Institute of Human Morphology, Moscow, Russia, Makarova O.V. ,   Research Institute of Human Morphology, Moscow, Russia,   Lomonosov Moscow State University, Moscow, Russia
Published: January 2021

Introduction. Stress is one of the factors contributing to the gastrointestinal tract diseases development and exacerbating the course of diseases of the gastrointestinal tract. The cold factor is the most common stress factor in Russia. Therefore, the aim of our work was to characterize the immune responses and colon morphological and functional changes during cold stress in male and female C57BL/6 mice. Materials and methods. We studied alterations in the subpopulation composition of peripheral blood lymphocytes and morphofunctional changes in the thymus, spleen, and colon in response to a course intermittent cold exposure during 35-minute sessions for 14 days at –20° in adult male and female C57BL/6 mice. Results. The volume fraction of the PALS zone of the spleen and the content of endocrine cells in the colon decreased in animals of both sexes in the cold stress conditions. In females, the number of platelets and leukocytes in the peripheral blood increased, the width of the subcapsular zone of the thymus decreased, and the volume fraction of the red spleen pulp increased. In males, in the peripheral blood, the absolute and relative content of T-regulatory lymphocytes decreased, and the relative content of activated T-helpers increased, the volume fraction of the light centers of lymphoid nodules in the spleen decreased, the length of the crypts increased in the colon. A number of differences between males and females of control groups were also revealed: in the peripheral blood, males had more platelets and the absolute content of T-regulatory lymphocytes and less absolute content of T-cytotoxic. In the colon of males, the content of proliferating epithelial cells in the colon was higher than the one in females, and the bulk density of goblet cells was lower in males. Conclusion. Under the cold stress factor exposure in animals, physiological stress develops. Immune reactions and colon morphofunctional changes in the colon during cold stress differ between males and females. Keywords:cold stress, sex differences, colon, immune system
Case report of tufting-enteropathy: course of the disease, complexity of morphological diagnosis
Authors:   Krasnoyarsk regional pathoanatomical bureau, Krasnoyarsk, Russia, Garkusha T.A. ,   V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk, Russia, Gappoev S.V. ,   Krasnoyarsk regional pathoanatomical bureau, Krasnoyarsk, Russia,   V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk, Russia, Khorzhevskii V.A. ,   Krasnoyarsk regional pathoanatomical bureau, Krasnoyarsk, Russia,   V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk, Russia, Levkovich L.G. ,   V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk, Russia
Published: January 2021

Tufting enteropathy (TE) is a rare autosomal recessive disease characterized by diarrhea starting in the neo-natal period. This disease was first described in 1994 by Reifen R.M. et al. The disease is caused by muta-tions in the cell adhesion molecule EpCAM. TE is characterized by alterations in the intestinal epithelium: surface enterocytes are primarily affected, and they form tufts. At the ultrastructural level, this disease is characterized by an increase in the length and number of desmosomes. This paper presents a clinical case of TE in a 3-month-old boy who was diagnosed based on clinical and morphological, electron microscopy findings. Diarrheal syndrome developed in the patient from the second day of life and persisted regardless of enteral nutrition and led to severe exsicosis. Keywords: tufting enteropathy, diarrhea, desmosome, enterocyte, microvilli
Evolution of forms of international scientific and technical cooperation in the USSR and the Russian Federation
Authors: Balkhaeva Sayana , Kapustin Anatolij , Simvolokov Oleg , Shulyatev Igor
Published: January 2021

International scientific and technical cooperation (ISTC) is one of the factors in the development of the modern economy. The foundations of international scientific and technical policy were laid in the USSR. The Russian Federation not only took over from the USSR a relatively large volume of international obligations in the field of ISTC, but also updated the legal instruments of state policy in this area, adapting them to the new conditions of modern international relations. The article examines the scale and significance of the changes, which have taken place, their relevance to modern challenges, which makes it possible to predict new forms of ISTC.
«Слово о полку Игореве»: реконструкция стихотворного текста
Authors:   Институт славяноведения РАН, Николаев Сергей Львович
Published: January 2021

В книге предлагается реконструкция текста «Слова о полку Игореве» как памятника древнерусской поэзии. В основе исследования лежит гипотеза о том, что «Слово» — стихотворное произведение, состоящее из стихотворных строк с разным количеством слогов. Каждая строка имеет индивидуальный метр; весь текст «Слова» прошит «лестничной» рифмовкой между смежными строками. Метрическая система «Слова о полку Игореве» может быть определена как неравносложная силлаботоника; такая же система обнаруживается и в некоторых других древнерусских текстах. Установление регулярной метрики в «Слове» стало возможным благодаря гипотезе (А. Ю. Чернов, А. В. Дыбо), согласно которой в памятнике представлено факультативное прояснение слабых редуцированных. Реконструкция ударения в «Слове» основывается на результатах позднепраславянской акцентологической реконструкции и данных древнерусского акцентологического словаря А. А. Зализняка (2014; 2019). Существенная часть книги посвящена языку «Слова», анализу лексических, морфологических и фонетических диалектизмов, реконструкции акцентуационной системы и вопросу о диалектной локализации памятника. Представленная в книге реконструкция «Слова» является первым опытом системного моделирования стихотворного текста на гипотетическом древнерусском диалекте XII–XIII в.
Ruthenians of the Austrian Empire in the diaries and memoirs of Russian officers who participated in the Hungarian campaign of 1849
Authors:   Institute of Slavic Studies, Russian Academy of Sciences, Dronov Mikhail Yu.
Published: January 2021

The book includes fragments from previously published texts by ten Russian officers – participants of the Hungarian campaign of 1849, who personally came into contact with the Ruthenian population of the Austrian Empire (the ancestors of modern Western Ukrainians and Carpatho-Rusyns). It is intended for researchers and a wide range of readers interested in the history and culture of Western Ukraine and Carpathian Rus’.
Ukuran Gejala Pusat Data belum dikelompokkan
Authors: Ibrahim Fery Maulana
Published: January 2021

Memecahkan masalah Ukuran gejala pusat data belum dikelompokan.
STAP2 is a differentially expressed gene in brain metastatic human breast cancer.
Authors: Mamoor Shahan
Published: January 2021

Metastasis to the brain is a clinical problem in patients with breast cancer (1-3). We mined published microarray data (4, 5) to compare primary and metastatic tumor transcriptomes for the discovery of genes associated with brain metastasis in humans with metastatic breast cancer. We found that signal-transducing adaptor protein 2, encoded by STAP2, was among the genes whose expression was most different in the brain metastases of patients with metastatic breast cancer as compared to primary tumors of the breast. STAP2 mRNA was present at increased quantities in brain metastatic tissues as compared to primary tumors of the breast. Importantly, expression of STAP2 in primary tumors was significantly correlated with patient distant metastasis-free survival. Modulation of STAP2 expression may be relevant to the biology by which tumor cells metastasize from the breast to the brain in humans with metastatic breast cancer.
TRIM62 is a differentially expressed gene in human metastatic breast cancer, in the brain and in the lymph nodes.
Authors: Mamoor Shahan
Published: January 2021

Metastasis to the brain is a clinical problem in patients with breast cancer (1-3). We mined published microarray data (4, 5) to compare primary and metastatic tumor transcriptomes for the discovery of genes associated with brain metastasis in humans with metastatic breast cancer. We found that the tripartite motif-containing 62, encoded by TRIM62, was among the genes whose expression was most different in the brain and lymph node metastases of patients with metastatic breast cancer. TRIM62 mRNA was present at increased quantities in brain metastatic tissues as compared to primary tumors of the breast. Importantly, expression of TRIM62 in primary tumors was significantly correlated with patient recurrence-free survival in patients with breast cancer. Modulation of TRIM62 expression may be relevant to the biology by which tumor cells metastasize from the breast to the brain while evading immune clearance in the lymph nodes in humans with metastatic breast cancer. These data are one piece of evidence suggesting a common ancestor or tumor clone for brain and lymph node metastases that originate from the primary tumor, alluding to patterns in developmental origin and migratory pathways through the lymph node in human brain metastatic breast cancer.
ukuran gejala pusat data dikelompokan
Authors: Dwiputra Valiza Sevtian
Published: January 2021

Statistika memiliki ruang lingkup yang sangat luas sehabis statistika tumbuh secara mandiri. Seluruh permasalahan yang berkaitan dengan informasi berbentuk angka bisa dipecahkan dengan memakai tata cara statistik. Dengan memakai statistik kita bisa membagikan cerminan, menyamakan serta menampilkan ikatan informasi ekonomi.Kemampuan statistika serta keahlian memakainya ialah sesuatu perihal yang sangat berarti serta sangat berguna untuk suatu organisasi industri spesialnya dalam bidang ekonomi serta bisnis. Sebab dengan itu, suatu organisasi industri dapat memperoleh data yang sangat bermanfaat untuk kemajuan perusahaannya. Data tersebut dapat didapatkan dari hasil pengolahan informasi yang sudadisimpulkan setelah itu informasi tersebut dapat kita analisa buat dijadikan bahan ditaksir dalam mengambil keputusan di masa yang hendak tiba.
Abundant transmission of Corona Virus Nsp2 RNA Topoisomerse I120F Mutants with Concurrence D614G Spike Protein Mutation in Australia
Authors: CHAKRABORTY ASIT KUMAR
Published: January 2021

We previously predicted Nsp2 Corona virus protein as RNA topoisomerase through amino acid homology among Vibrio haemolytica DNA topoisomerase IA/IV as well as DNA primase, DNA gyrase and bi-subunit Trypanosoma brucei DNA topoisomerase IB. Many DNA topoisomerase I/III have RNA topoisomerase activity and such ubiquitous enzymes are conserved and involved in the regulation of replication and transcription. We have checked here mutational profile of Nsp2 RNA topoisomerase analyzing >10000 orf1a 4405 amino acid length Corona virus polyprotein. Mutant proteins were selected by BLAST search having 99.84% sequence similarity and 181-818aa portion Nsp2 protein (protein id. QIU82057) was analyzed using CLUSTAL Omega software. We found 26 different mutations where most changes were selected at Isoleucine and Alanine into Valine or Leucine into Phenylanaline pinpointing conserved nature of the Corona virus RNA topoisomerase. Major nonsense very abundant mutations were found at I120F (Isoleucine to Phenylalanine). Other important mutations were R27C, I198V, T85I, L410F, I559V and P583S. The I120F mutation was abundant in Australian isolates and its spread was seen in the Bangladesh and other countries like USA. We suggest that abundant I120F mutation of Nsp2 Topoisomerase may increase transmission of Corona virus by stabilizing RNA structure for efficient virus pakaging. Interestingly, such mutations were found in association of D614G mutation of Spike protein, known to >70% increase infectivity. On the contrary, all P583S Nsp2 mutants analyzed had no concurrence D614G spike protein mutation. Many silent mutations (5-7) were detected by genome wide analysis but no N501Y Spike protein mutation. This is first report that predicts a link of greater Corona virus transmission with Nsp2 protein I120F and spike protein D614G mutations.
Văn hóa doanh nghiệp thời kì mới
Authors: AISDL
Published: January 2021

(CTG) Việc hội nhập ASEAN tạo ra tiềm năng lớn để các nước có thể chuyển dịch cơ cấu và phát triển kinh tế như cơ hội về mở rộng xuất nhập khẩu, đầu tư, chia sẻ học tập kinh nghiệm xây dựng an sinh xã hội nhằm đảm bảo phát triển bền vững. Với quy mô nguồn nhân lực dồi dào và cơ cấu dân số vàng, người lao động lại được đánh giá cần cù, chăm chỉ, thông minh... Việt Nam sẽ hướng tới nâng cao chất lượng lao động đáp ứng hội nhập.
Superspreading: The engine of the SARS-CoV-2 pandemic
Authors: Salas Antonio , Bello Xabier , Pardo-Seco Jacobo , Martinón-Torres Federico , Gomez-Carballa Alberto
Published: January 2021

A growing amount of evidence point to a key role of superspreaders in the SARS-CoV-2 pandemic. A few superspreader events have been recently reported (e.g. Boston (USA), Spain); each of them has been responsible for important coronavirus local outbreaks. By examining >160K SARS-CoV-2 entire genomes from the GISAID database, we were able to detect hundreds of these events (including those already reported in the literature) that have occurred worldwide since the beginning of the pandemic.
Cultural Artditivity
Authors: Vuong Quan-Hoang , Ho Manh-Toan , Ho Tung Manh , Nguyen Minh-Hoang , Nguyen Hong-Kong T.
Published: January 2021

As a cultural product, arts are generally comprehensible across cultures. However, even though every story has already been told, not every person resonates with a story similarly. In a way, the culture of a cultural product cannot be added to a person’s core cultural value. As a consumer, a person needs to accept cultural elements in a story, even though those elements might contradict their existing beliefs. The process of cultural additivity in experiencing arts can be explained by the mindsponge mechanism.
Văn minh làm giàu từ góc nhìn của một người Việt
Authors: AISDL
Published: January 2021

(Dân trí) - Bạn hãy thử hình dung một bức tranh thể hiện hình ảnh một thương gia cưỡi một chú lạc đà. Dưới chân họ chỉ có cát nóng bỏng của sa mạc khô cằn, phía sau lưng họ là ánh mặt chời chói lòa, bỏng rát. Hai bên đường chỉ có sương rồng gai góc, như biểu trưng cho hành trình vất vả đầy chông gai. Một điều gây bất ngờ: chú lạc đà lại kéo theo một chiếc xe hơi sang trọng.
PENDALAMAN MATA KULIAH SOCIOLINGUISTICS VARIASI SOSIAL PENGGUNA BAHASA
Authors: Asrifan Andi
Published: January 2021

Variasi sosial pengguna bahasa yang pertama ditinjau dari segi status sosial. Status sosial terdapat dalam kelas sosial. Sumarsono (2007: 43) menjelaskan bahwa kelas sosial mengacu pada golongan masyarakat yang mempunyai kesamaan tertentu dalam bidang kemasyarakatan seperti ekonomi, pekerjaan, pendidikan, kedudukan, kasta, dan sebagainya. Kasta biasanya dianggap sebagai salah satu jenis kelas sosial. Akan tetapi, menurut Sumarsono (2007: 44), ada satu hal yang dapat membedakan kasta dari kelas sosial yang lain, yaitu pada kasta orang tidak boleh seenaknya bebas memasuki golongan. Kasta bersifat tertutup sedangkan kelas sosial lain bersifat terbuka yang memungkinkan adanya mobilitas sosial, yaitu berpindahnya seseorang dari kelas ke kelas.
The Primary Pitfalls on the Road to Understanding Consciousness
Authors: Sipfle Karl
Published: January 2021

Consciousness and the human mind have been pondered for centuries [1] [2]. Today the most fundamental, likely outlines of the explanation of consciousness are known, and from this landscape we are well-positioned to fill in the basket of specific theories that will include the correct one. However, many errors in thinking and assumptions have accumulated, and even gained fashion, that obscure our progress. It is time to eliminate these, which we do herein by enumerating the complementary true assertions. Following that we mention four principles for choosing direction for further work. We conclude with a framework for further progress.
The Devil is Mainly in the Nuisance Parameters: Performance of Structural Fit Indices Under Misspecified Structural Models in SEM
Authors: Heene Moritz , Maraun Michael , Glushko Nadine J. , Pornprasertmanit Sunthud
Published: January 2021

To provide researchers with a means of assessing the fit of the structural component of structural equation models, structural fit indices- modifications of the composite fit indices, RMSEA, SRMR, and CFI- have recently been developed. We investigated the performance of four of these structural fit indices- RMSEA-P, RMSEA_S, SRMR_S, and CFI_S-, when paired with widely accepted cutoff values, in the service of detecting structural misspecification. In particular, by way of simulation study, for each of seven fit indices- 3 composite and 4 structural-, and the traditional chi-square test of perfect composite fit, we estimated the following rates: a) Type I error rate (i.e., the probability of (incorrect) rejection of a correctly specified structural component), under each of four degrees of misspecification in the measurement component; and b) Power (i.e., the probability of (correct) rejection of an incorrectly specified structural model), under each condition formed of the pairing of one of three degrees of structural misspecification with one of four degrees of measurement component misspecification. In addition to sample size, the impacts of two model features, incidental to model misspecification- number of manifest variables per latent variable and magnitude of factor loading- were investigated. The results suggested that, although the structural fit indices performed relatively better than the composite fit indices, none of the goodness-of-fit index with a fixed cutoff value pairings was capable of delivering an entirely satisfactory Type I error rate/Power balance, [RMSEA_S,.05] failing entirely in this regard. Of the remaining pairings; a) RMSEA-P and CFI_S suffered from a severely inflated Type I error rate; b) despite the fact that they were designed to pick up on structural features of candidate models, all pairings- and especially, RMSEA-P and CFI_S- manifested sensitivities to model features, incidental to structural misspecification; and c) although, in the main, behaving in a sensible fashion, SRMR_S was only sensitive to structural misspecification when it occurred at a relatively high degree.
An Exploration of Staff Member’s Experiences of Receiving Clinical Supervision using Virtual Platforms, during the Covid-19 Pandemic
Authors: Chaisty Frances , Cunningham Roisin
Published: January 2021

AbstractBackground: Supervision is an integral part of standard practice within Clinical Psychology. Following the COVID-19 outbreak, much of the UK’s population were required to work from home, leading to an increase in supervision being conducted via virtual platforms.Objective: To explore clinical health psychology staff members’ experiences of receiving supervision virtually. Method: A mixed-methods approach was adopted to explore 12 practitioners experience of remote supervision. This was completed online and consisted of the Supervisory Relationship Questionnaire and eight open-ended questions. Descriptive data were analysed using Microsoft Excel and qualitative data were analysed using thematic analysis. Results: Participant’s ratings of the supervisory relationship were high. Overall, practitioners found virtual supervision positive, but still preferred face to face supervision. Clinician’s reported that the pre-established relationship with supervisors was important and building a new supervisory relationship virtually was more challenging. Discussion: This study highlights the importance of monitoring supervisory relationships whilst supervision is delivered virtually. Recommendations made by participants for virtual supervision should be used to support this.
Segmentation of root and pattern morphology
Authors: Finley Sara , Newport Elissa
Published: January 2021

Morphology is the study of how form and meaning are combined to form complex words. While previous studies of morphology learning rely on semantic associations of continuous affixes (e.g., prefixes and suffixes), the present study focuses on the learnability of non-continuous (non-concatenative) forms, without the use of semantic information. We performed three artificial grammar learning experiments testing the types of information that adult, English speaking learners can extract from hearing words made up of CCC ‘roots’. In Experiment 1, participants were exposed to 24 CVCVC words made up of 12 CCC roots and four VV residues, repeated 15 times. In Experiments 2 and 3 the number of CCC items was increased to 72 (repeated five times), but with four additional templates (e.g., CVCCV in addition to CVCVC) in Experiment 2, and the addition of a prefix in Experiment 3. The results were parallel across all three experiments: participants could readily identify familiar items compared to both ungrammatical and novel grammatical items, and could correctly identify novel words compared to ungrammatical items, but only when the ungrammatical item was sufficiently different from the items heard in training. These results suggest that while learners can extract discontinuous information from lexical items, learners rely heavily on their memory for these lexical items, suggesting a possible bias against learning non-concatenative morphology.
SOCIO-ECONOMIC EFFECTS OF THE COVID-19 PANDEMIC IN THE GULF MONARCHIES
Authors:   INION RAN, Bibikova Olga , Zhilina Irina
Published: January 2021

The article reviews aspects of coronavirus spread of in member-countries of the Cooperation Council for the Arab States of the Gulf. The measures taken by the governments of these countries to curb the spread of the COVID-19 pandemic as well as to support people and businesses are highlighted.
A New Two-Parameter Lindley Distribution
Authors: Shanker Rama , Rahman Umme Habibah
Published: January 2021

In this paper, a new two-parameter Lindley distribution has been proposed. Descriptive statistical properties along with order statistics, Fisher information matrix and confidence interval of the proposed distribution have been discussed. Parameters are estimated by the method of Maximum Likelihood estimation. A real lifetime data has been presented to test the goodness of fit of the proposed distribution over other one parameter and two –parameter Lindley family of distributions.
3n+1 Problem and its Dynamics
Authors: Subedi Bishnu Hari , Singh Ajaya
Published: January 2021

The subject of this paper is the well-known 3n + 1 problem of elementary number theory. This problem concerns with the behaviour of the iteration of a function which takes odd integers n to 3n + 1, and even integers n to n/2. There is a famous Collatz conjecture associated to this problem which asserts that, starting from any positive integer n, repeated iteration of the function eventually produces the value. We briefly discuss some basic facts and results of 3n + 1 problem and Collatz conjecture. Basically, we more concentrate on the generalization of this problem and conjecture to holomorphic dynamics.
An Alternative Proof of Rubin's Lemma
Authors: Ghimire Santosh
Published: January 2021

Rubin's Lemma is an inhomogenous type inequality which is satisfied by the sequence of dyadic martingales. In this paper, we give a proof using the measure theoretic approach which is simpler and different than the original probabilistic approach.
Basic Operations on Vedic Mathematics: A Study on Special Parts
Authors: Parajuli Krishna Kanta
Published: January 2021

Vedic Mathematics was rediscovered and reconstructed by Sri Bharati Krishna Tirthaji from ancient Sanskrit texts Veda early last century between 1911 – 1918 is popularly known today is Vedic Mathematics. It is an extremely refined, independent and efficient mathematical system based on his 16 formulae and some sub-formulae with simple rules and principles.

The main purpose of this paper is to communicate a new approach to Mathematics, offering simple, direct, one-line, mental solutions to mathematical problems. In the way of basic mathematical operations like addition, subtraction, multiplication and division can be done in simple ways, and results are obtained quickly and can be checked in a minute by using the Vedic techniques. In this system, for any problem, there is always one general technique and also some special pattern problems. This paper especially concentrates only on the specific pattern of elementary operation of Vedic Mathematics.
Public Service Bureaucratic Reform: A Case Study on Coordination in One Stop Services (KPTSP) in Takalar Regency
Authors: Susanti Gita , Rifany Rifany
Published: January 2021

Bureaucratic services tend not to improve their performance and carry out reforms. Service users are often faced with so many problems when they are dealing with bureaucracy. The purpose of this study is to describe the reform of the Public Service Bureaucracy in terms of coordination in One Stop Services (KPTSP) in Takalar Regency. In this study, a qualitative approach was used. The type of research used in this research is descriptive research type. The results showed that hierarchical mechanisms in the form of a structured flow of coordination and power need each other to establish cooperation within organizational units. The market mechanism shows that the change in the bureaucracy from services to revenue to provide income for the region through the collection of fees. Licensing and providing incentives can improve the performance of One-Stop Services, Takalar District has a network mechanism that is interrelated and needs each other, this can be seen from the requirements given by the Service Agency One-Stop Integrated Takalar Regency that asks for recommendations from related Regional Work Units (SKPD).
FEATURES OF THE USE OF ADVERTISING CAMPAIGNS IN THE TOURISM SECTOR
Authors:   Odessa National Economic University, Nazarenko Olga V. , Martynova Natalia S. ,   Odessa National Economic University
Published: January 2021

In recent decades, the development of the tourism industry has been a worldwide trend. The interest shown in the development of the tourism sector is associated not only with the fact that the industry is developing dynamically but also with the fact that the development of tourism affects almost all key sectors of the economy. The task of the activities of tourist enterprises is the organization of comprehensive services for tourists. Services in tourism are varied ‒ transportation, accommodation, meals, excursions, entertainment, and personal services etc.The tourism sector is characterized by such characteristics as rapid growth rates, continuous improvement of the industry, and a high level of competition. That is why the success of enterprises in this area largely depends on carefully implemented advertising campaigns as one of the main elements of the communication complex and marketing strategy.Advertising campaigns in the tourism sector have their own characteristics and play an essential role in the lives of consumers when choosing travel products and services. The popularity of a travel product is largely due to how well the potential client is aware of it. And this is one of the main functions of advertising campaigns in the tourism industry. Advertising campaigns, like any other type of marketing communications, play an important role in implementing the strategy of tourism enterprises. With the help of advertising, they are developing new markets, and as a means of competition, advertising campaigns exacerbate it, helping to improve the quality of tourist services.The purpose of the article is to explore and analyze the features of the use of advertising campaigns in the tourism industry, to identify the positive and negative aspects, as well as prospects in this area.The relevance of the topic of the article is significant, because tourism is one of the largest and most dynamic sectors of the economy. High rates of its development, large volumes of foreign exchange earnings actively affect various sectors of the economy and contribute to the formation of a full-fledged tourism industry.