bluuebunny/crossref_metadata_2025 huggingface dataset:
Report on the 1st Workshop on Reaching Efficiency in Neural Information Retrieval (ReNeuIR 2022) at SIGIR 2022
Authors: Bruch Sebastian , Lucchese Claudio , Nardini Franco Maria
Published: January 2023

As Information Retrieval (IR) researchers, we not only develop algorithmic solutions to hard problems, but we also insist on a proper, multifaceted evaluation of ideas. The IR literature on the fundamental topic of retrieval and ranking, for instance, has a rich history of studying the effectiveness of indexes, retrieval algorithms, and complex machine learning rankers and, at the same time, quantifying their computational costs, from creation and training to application and inference. This is evidenced, for example, by more than a decade of research on efficient training and inference of large decision forest models in Learning to Rank (LtR). As we move towards even more complex, deep learning models in a wide range of applications, questions on efficiency have once again become relevant with renewed urgency. Indeed, efficiency is no longer limited to time- and space-efficiency; instead it has found new, challenging dimensions that stretch to resource-, sample- and energy-efficiency with ramifications for researchers, users, and the environment.

As a step towards bringing together experts from industry and academia and creating a forum for a critical discussion and the promotion of efficiency in the era of Neural Information Retrieval (NIR), we held the ReNeuIR workshop on July 15

th

, 2022 as a hybrid event---in person in Madrid, Spain along with online attendees---in conjunction with ACM SIGIR 2022. Recognizing the importance of this topic, approximately 80 participants answered our call and attended the workshop over three sessions. The event included a total of two keynotes and eight paper presentations, and concluded with a lively discussion where participants helped identify gaps in existing research and brainstormed future research directions. We had consensus in recognizing that efficiency is not simply latency, that a holistic, concrete definition of efficiency is needed to guide researchers and reviewers alike, and that more research is necessary in the development of efficiency-centered evaluation metrics and standard benchmark datasets, platforms, and tools.

Date:
15 July, 2022.

Website:
https://ReNeuIR.org.
Report on the 13th Conference and Labs of the Evaluation Forum (CLEF 2022)
Authors: Barrón-Cedeño Alberto , Da San Martino Giovanni , Esposti Mirko Degli , Faggioli Guglielmo , Ferro Nicola , Hanbury Allan , Macdonald Craig , Pasi Gabriella , Potthast Martin , Sebastiani Fabrizio
Published: January 2023

This is a report on the thirteenth edition of the
Conference and Labs of the Evaluation Forum
(CLEF 2022), held on September 5--8, 2022, in Bologna, Italy. CLEF was a four-day hybrid event combining a conference and an evaluation forum. The conference featured keynotes by Benno Stein and Rita Cucchiara, and presentation of peer-reviewed research papers covering a wide range of topics, in addition to many posters. The evaluation forum consisted of fourteen labs: ARQMath, BioASQ, CheckThat!, ChEMU, eRisk, HIPE, iDPP, ImageCLEF, JokeR, LeQua, LifeCLEF, PAN, SimpleText, and Touché, addressing a wide range of tasks, media, languages, and ways to go beyond standard test collections.

Date:
5--8 September, 2022.

Website:
https://clef2022.clef-initiative.eu/.
Was Fairness in IR Discussed by Cooper and Robertson in the 1970's?
Authors: Hiemstra Djoerd
Published: January 2023

I discuss fairness in Information Retrieval (IR) through the eyes of Cooper and Robertson's probability ranking principle. I argue that unfair rankings may arise from blindly applying the principle without checking whether its preconditions are met. Following this argument, unfair rankings originate from the application of learning-to-rank approaches in cases where they should not be applied according to the probability ranking principle. I use two examples to show that fairer rankings may also be more relevant than rankings that are based on the probability ranking principle.
Answering Topical Information Needs Using Neural Entity-Oriented Information Retrieval and Extraction
Authors: Chatterjee Shubham
Published: January 2023

In the modern world, search engines are an integral part of human lives. The field of Information Retrieval (IR) is concerned with finding material (usually documents) of an unstructured nature (usually text) that satisfies an information need (query) from within large collections (usually stored on computers). The search engine then displays a ranked list of results relevant to our query. Traditional document retrieval algorithms match a query to a document using the overlap of words in both. However, the last decade has seen the focus shifting to leveraging the rich semantic information available in the form of
entities.

Entities are uniquely identifiable objects or things such as places, events, diseases, etc. that exist in the real or fictional world. Entity-oriented search systems leverage the semantic information associated with entities (e.g., names, types, etc.) to better match documents to queries. Web search engines would provide better search results if they understand the meaning of a query.

This dissertation advances the state-of-the-art in IR by developing novel algorithms that understand text (query, document, question, sentence, etc.) at the semantic level. To this end, this dissertation aims to understand the fine-grained meaning of entities from the context in which the entities have been mentioned, for example, "oysters" in the context of food versus ecosystems. Further, this dissertation aims to automatically learn (vector) representations of entities that incorporate this fine-grained knowledge and knowledge about the query. This dissertation refines the automatic understanding of text passages using deep learning, a modern artificial intelligence paradigm.

This dissertation utilizes the semantic information extracted from entities to retrieve materials (text and entities) relevant to a query. The interplay between text and entities in the text is studied by addressing three related prediction problems: (1) Identify entities that are relevant for the query, (2) Understand an entity's meaning in the context of the query, and (3) Identify text passages that elaborate the connection between the query and an entity.

The research presented in this dissertation may be integrated into a larger system designed for answering complex topical queries such as
dark chocolate health benefits
which require the search engine to automatically understand the connections between the query and the relevant material, thus transforming the search engine into an answering engine.

Awarded by:
University of New Hampshire, Durham, USA on 1 September 2022.

Supervised by:
Laura Dietz.

Available at:
https://scholars.unh.edu/dissertation/2714/.
Remembering the Work of Phillip L. Geissler: A Coda to His Scientific Trajectory
Authors: Bowman Gregory R. , Cox Stephen J. , Dellago Christoph , DuBay Kateri H. , Eaves Joel D. , Fletcher Daniel A. , Frechette Layne B. , Grünwald Michael , Klymko Katherine , Ku JiYeon , Omar Ahmad K. , Rabani Eran , Reichman David R. , Rogers Julia R. , Rosnik Andreana M. , Rotskoff Grant M. , Schneider Anna R. , Schwierz Nadine , Sivak David A. , Vaikuntanathan Suriyanarayanan , Whitelam Stephen , Widmer-Cooper Asaph
Published: January 2023

Phillip L. Geissler made important contributions to the statistical mechanics of biological polymers, heterogeneous materials, and chemical dynamics in aqueous environments. He devised analytical and computational methods that revealed the underlying organization of complex systems at the frontiers of biology, chemistry, and materials science. In this retrospective we celebrate his work at these frontiers.
Exogenous succinate impacts mouse brown adipose tissue mitochondrial proteome and potentiates body mass reduction induced by liraglutide
Authors: Gaspar Rodrigo S. , Delafiori Jeany , Zuccoli Giuliana , Carregari Victor Corasolla , Prado Thais P. , Morari Joseane , Sidarta-Oliveira Davi , Solon Carina S. , Catharino Rodrigo R. , Araujo Eliana P. , Martins-de-Souza Daniel , Velloso Licio A.
Published: February 2023

Exogenous succinate induces major changes in brown adipose tissue protein expression affecting particularly mitochondrial respiration and structural proteins. When given exogenously in drinking water, succinate mitigates body mass gain in a rodent model of diet-induced obesity; in addition, when given in association with the glucagon-like peptide-1 receptor agonist, liraglutide, succinate increases body mass reduction promoted by liraglutide alone.
Altered cutaneous reflexes to non-noxious stimuli in the triceps surae of people with chronic incomplete spinal cord injury
Authors: Phipps Alan M. , Thompson Aiko K.
Published: February 2023

This study examined modulation of the triceps surae cutaneous reflexes during standing and walking and the relationship between cutaneous and H-reflexes in people with chronic incomplete spinal cord injury (SCI). In people with SCI, the normal task-dependent, nerve-specific modulation of triceps cutaneous reflexes was missing. Cutaneous and H-reflexes were not correlated. Together with other spinal reflexes, cutaneous reflexes may serve as important biomarkers for the state of spinal interneuronal pathways.
Accurate Diagnosis and Treatment of Painful Temporomandibular Disorders: A Literature Review Supplemented by Own Clinical Experience
Authors: Garstka Adam Andrzej , Kozowska Lidia , Kijak Konrad , Brzózka Monika , Gronwald Helena , Skomro Piotr , Lietz-Kijak Danuta
Published: January 2023

Introduction. Temporomandibular disorders (TMD) is a multifactorial group of musculoskeletal disorders often with combined etiologies that demand different treatment plans. While pain is the most common reason why patients decide to seek help, TMD is not always painful. Pain is often described by patients as a headache, prompting patients to seek the help of neurologists, surgeons, and ultimately dentists. Due to the unique characteristics of this anatomical area, appropriate diagnostic tools are needed, as well as therapeutic regimens to alleviate and/or eliminate the pain experienced by patients. Aim of the Study. The aim of this study is to collect and organize information on the diagnosis and treatment of pain in TMD, through a review of the literature supplemented by our own clinical experience. Material and Methods. The study was conducted by searching scientific databases PubMed, Scopus, and Google Scholar for documents published from 2002–2022. The following keywords were used to build the full list of references: TMD, pain, temporomandibular joint (TMJ), TMJ disorders, occlusal splint, relaxing splints, physiotherapy TMD, pharmacology TMD, natural therapy TMD, diagnostic criteria for TMD, and DC/TMD. The literature review included 168 selected manuscripts, the content of which was important for pain diagnosis and clinical treatment of TMD. Results. An accurate diagnosis of TMD is the foundation of appropriate treatment. The most commonly described treatments include physiotherapy, occlusal splints therapy, and pharmacological treatment tailored to the type of TMD. Conclusions. Based on the literature review and their own experience, the authors concluded that there is no single ideal form of pain therapy for TMD. Treatment of TMD should be based on a thorough diagnostic process, including the DC/TMD examination protocol, psychological evaluation, and cone beam computer tomography (CBCT) imaging. Following the diagnostic process, once a diagnosis is established, a treatment plan can be constructed to address the patient’s complaints.
Extremum Options Pricing of Two Assets under a Double Nonaffine Stochastic Volatility Model
Authors: Ou Shubin , Deng Guohe
Published: February 2023

In this paper, we consider the pricing problem for the extremum options by constructing a double nonaffine stochastic volatility model. The joint characteristic function of the logarithm of two asset prices is derived by using the Feynman–Kac theorem and one‐order Taylor approximation expansion. The semiclosed analytical pricing formulas of the European extremum options including option on maximum and option on minimum of two underlying assets are derived by using measure change technique and Fourier transform approach. Some numerical examples are provided to analyze the pricing results of extremum options under affine model, nonaffine model, Black–Scholes model, and the influences of some model parameters on the option. Numerical results show that the analytical pricing formulas have higher computational efficiency and accuracy than those of Monte Carlo simulation method. Also, results of sensitivity analysis report that the nonaffine models are more effective than other existing models in capturing the effect of volatility on option pricing.
Supply Chain Resilience of Mineral Resources Industry in China
Authors: Jiang Rui , Liu Chunxue , Liu Xiaowei , Zhang Shuai
Published: January 2023

Improving the supply chain resilience of the mineral resources industry is crucial for ensuring national economic security in China. Based on the supply and demand data of China’s mineral resources industry from 2002 to 2018, this study adopts system dynamics model to simulate the supply chain resilience of the mineral resources industry, the mining industry, and the smelting and processing industry under the scenario of steady economic development and the scenario of supply chain crisis. From the simulation results, the reserves of the mineral resources industry and the smelting and processing industry under the two scenarios are nearly the same, indicating that they are weakly affected by the foreign market, and both have strong resilience. The mining industry has a high dependence on imports and a lack of supply chain resilience. Under the condition of steady economic development, the output of the mining industry needs to develop at a low speed to reduce production capacity. More attention should be paid to the high level of import dependence and insufficient supply chain resilience of the mining industry. In the stable international trade situation, reserves of important minerals should be increased to alleviate the resource shortage during the supply chain crisis.
Ensemble Learning-Based Hybrid Segmentation of Mammographic Images for Breast Cancer Risk Prediction Using Fuzzy C-Means and CNN Model
Authors: Jha Sudan , Ahmad Sultan , Arya Anoopa , Alouffi Bader , Alharbi Abdullah , Alharbi Meshal , Singh Surender
Published: January 2023

The research interest in this field is that females are not aware of their health conditions until they develop tumour, especially when breast cancer is concerned. The breast cancer risk factors include genetics, heredity, and sedentary lifestyle. The prime concern for the mortality rate among females is breast cancer, and breast cancer is on the rise, both in rural and urban India. Women aged 45 or above are more vulnerable to this disease. Images are more effective at depicting information as compared to text. With the advancement in technology, several computerized techniques have come up to extract hidden information from the images. The processed images have found their application in several sectors and medical science is one of them. Disease-like breast cancer affects most women universally and it happens due to the existence of breast masses in the breast region for the development of breast cancer in women. Timely breast cancer detection can also increase the rate of effective treatment and the survival of women suffering from breast cancer. This work elaborates the method of performing hybrid segmentation techniques using CLAHE, morphological operations on mammogram images, and classified images using deep learning. Images from the MIAS database have been used to obtain readings for parameters: threshold, accuracy, sensitivity, specificity rate, biopsy rate, or a combination of all the parameters and many others under study.
Cone Beam CT Analysis of Haller Cells: Prevalence and Relationship with Orbital Floor Dehiscence
Authors: Moshfeghi Mahkameh , Dehini Hamidreza , Ghazizadeh Ahsaie Mitra
Published: February 2023

Background and Aim. Haller cells arise from anterior ethmoid air cells and are located in the medial orbital floor, lateral to the maxillary infundibulum. The aim of this cross-sectional study was to determine the prevalence of the Haller cells and its relationship with orbital floor dehiscence on cone beam CT images. Materials and Methods. CBCT images of 120 patients were interpreted in coronal plane for the presence of Haller cells and orbital floor dehiscence. The prevalence of Haller cell, presence of dehiscence, unilateral, or bilateral frequency were assessed. In addition, the size was categorized in three groups of small, medium, and large. Chi-square and Cochran–Mantel–Haenszel tests were used for statistical analysis of the data, and

p
<
0.05

was considered to be significant. Results. A total of 51 male and 69 female with mean ± SD age of 38.84 ± 68.14 were assessed. The overall prevalence of Haller cells was 56.7%, of which 44 (64.7%) were unilateral and 24 were bilateral (35.3%). The majority of the cells (70.7%) were seen in medium (2–4 mm) sized. There was a significant association between Haller cells and orbital floor dehiscence (

p
≤
0.001

). Conclusion. The prevalence of Haller cells was remarkably high and the presence of Haller cells was strongly associated with ipsilateral orbital floor dehiscence. Based on the findings of this study, CBCT can be useful in delineation of the bony anatomy of sinonasal complex.
Chitosan Nanoparticles Alleviated the Adverse Effects of Sildenafil on the Oxidative Stress Markers and Antioxidant Enzyme Activities in Rats
Authors: Sheweita Salah A. , Alian Dalia M. Elsayed , Haroun Medhat , Nounou Mohamed Ismail , Patel Ayyub , El-Khordagui Labiba
Published: January 2023

Sildenafil (SF) is widely used for erectile dysfunction and other conditions, though with limitations regarding oral absorption and adverse effects. Despite nanotechnological improvements, the effect of nanocarriers on SF hepatotoxicity has not been documented to date. This study aimed at assessing the impact of chitosan nanoparticles either uncoated (CS NPs) or Tween 80-coated (T-CS NPs) on the effects of SF on oxidative stress markers and antioxidant enzyme activities in rats. Test SF-CS NPs prepared by ionic gelation were uniform positively charged nanospheres (diameter 178-215 nm). SF was administered intraperitoneally to male rats (1.5 mg/kg body weight) in free or nanoencapsulated forms as SF-CS NPs and T-SF-CS NPs for 3 weeks. Free SF significantly suppressed the activity of the antioxidant enzymes glutathione S-transferase (GST), glutathione peroxidase (GPx), glutathione reductase (GR), catalase (CAT), and superoxide dismutase (SOD), as well as the levels of glutathione (GSH) and thiobarbituric acid reactive substances (TBARS) as in an indirect measure of free radicals. Interestingly, SF-CS NPs and T-SF-CS-NPs treatments significantly attenuated the inhibitory effects of SF on the activity of these enzymes whereas, GST activity was inhibited. Moreover, the protein expression of GST was downregulated upon treatment of rats with free SF, SF-CS-NPs, and T-SF CS-NPs. In contrast, the activity and protein expression of GPx was induced by SF-CS NPs and T-SF-CS-NPs treatments. The histopathological study showed that SF induced multiple adverse effects on the rat liver architecture which were markedly suppressed particularly by T-SF-CS NPs. In conclusion, chitosan nanoencapsulation of SF counteracted the adverse effects of SF on the activity of antioxidant enzymes and liver architecture. Findings might have significant implications in improving the safety and efficacy of SF treatment of the widely expanding disease conditions.
Choice of Survival Metric and Its Impacts on Cancer Survival Estimates for American Indian and Alaska Native People
Authors: Nash Sarah H. , Wahlen Madison M. , Meisner Angela L W. , Morawski Bożena M.
Published: February 2023

Background:

Different survival metrics have different applicability to clinical practice and research. We evaluated how choice of survival metric influences assessment of cancer survival among American Indian and Alaska Native (AIAN) people relative to non-Hispanic Whites (NHW). A secondary objective was to present variations in survival among AIAN people by age, sex, stage, and Indian Health Service (IHS) region.

Methods:

Five-year survival was calculated using the North American Association of Central Cancer Registries Cancer in North America dataset. We calculated survival among AIAN people, compared with NHW using four approaches: (i) observed (crude) survival, (ii) cause-specific survival, (iii) relative survival using age- and sex-adjusted lifetables, and (iv) relative survival using lifetables additionally adjusted for race, geography, and socioeconomic status. For AIAN people, we evaluated how survival varied by age, stage at diagnosis, and IHS region.

Results:

Observed survival methods produced the lowest estimates, and—excepting prostate cancer—cause-specific methods produced the highest survival estimates. Survival was lower among AIAN people than NHW for all methods. Among AIAN people, survival was higher among those 20–64 years, females, and tumors diagnosed at local stage. Survival varied by IHS region and cancer sites.

Conclusions:

These results support the assertion that using the same methodology to compare survival estimates between racial and ethnic groups is of paramount importance, but that the choice of metric requires careful consideration of study objectives.

Impact:

These findings have the potential to impact choice of survival metric to explore disparities among AIAN people.
Payload-Binding Fab Fragments Increase the Therapeutic Index of MMAE Antibody–Drug Conjugates
Authors: Bordeau Brandon M. , Nguyen Toan Duc , Polli Joseph Ryan , Chen Ping , Balthasar Joseph P.
Published: February 2023

Monomethyl auristatin E (MMAE) is a potent tubulin inhibitor that is used as the payload for four FDA-approved antibody–drug conjugates (ADC). Deconjugated MMAE readily diffuses into untargeted cells, resulting in off-target toxicity. Here, we report the development and evaluation of a humanized Fab fragment (ABC3315) that enhances the therapeutic selectivity of MMAE ADCs. ABC3315 increased the IC50 of MMAE against human cancer cell lines by > 500-fold with no impact on the cytotoxicity of MMAE ADCs, including polatuzumab vedotin (PV) and trastuzumab-vc-MMAE (TvcMMAE). Coadministration of ABC3315 did not reduce the efficacy of PV or TvcMMAE in xenograft tumor models. Coadministration of ABC3315 with 80 mg/kg TvcMMAE significantly (P < 0.0001) increased the cumulative amount of MMAE that was excreted in urine 0 to 4 days after administration from 789.4±19.0 nanograms (TvcMMAE alone) to 2625±206.8 nanograms (for mice receiving TvcMMAE with coadministration of ABC3315). Mice receiving 80 mg/kg TvcMMAE and PBS exhibited a significant drop in white blood cell counts (P = 0.025) and red blood cell counts (P = 0.0083) in comparison with control mice. No significant differences, relative to control mice, were found for white blood cell counts (P = 0.15) or for red blood cell counts (P = 0.23) for mice treated with 80 mg/kg TvcMMAE and ABC3315. Coadministration of ABC3315 with 120 mg/kg PV significantly (P = 0.045) decreased the percentage body weight loss at nadir for treated mice from 11.9%±7.0% to 4.1%±2.1%. Our results demonstrate that ABC3315, an anti-MMAE Fab fragment, decreases off-target toxicity while not decreasing antitumor efficacy, increasing the therapeutic window of MMAE ADCs.
The simulation analysis of stator flux droop minimization in direct torque control open-end winding induction machine
Authors: Aihsan Muhammad Zaid , Jidin Auzani , Ahmad Tarusan Siti Azura , Sutikno Tole
Published: January 2023

Direct torque control (DTC) using dual-inverter technique is one of the best topologies for electric vehicle (EV) as it offers abundant selection of voltage vectors to drive the induction machine (IM). This dual-inverter technique also more reassuring as the system still workable even any of its voltage supply is disrupted or the power pack is drained. However, during the uneven voltage supply, the movement of voltage vectors is interrupted and will move obliquely especially in medium voltage vectors. This situation will lead to the faulty movement of the voltage vectors in the default sector definitions and lead to huge flux droop, which later could impose to distort phase current. This paper proposes an optimal sector definition based on the preset voltage ratio between the two inverters. The voltage vectors can be mapped tangentially to the flux vector, minimizing the flux droop and improving the phase current waveform when the proposed sector is utilized. The effectiveness of the proposed sector is tested using MATLAB/Simulink software and the exact parameter from the induction machine.
Pharmacopuncture with a low dosage of B complex vitamins in the Da Zhui acupoint (Governing Vessel 14) for controlling gastrointestinal parasitism in periparturient ewes
Authors: Rosalinski-Moraes Fernanda , Troncha Paula Mara , Oliveira Wilson Junior , Siqueira Marco Túlio Santos , Paiva Vinícius Vieira de , Scognamillo Márcia Valéria Rizzo
Published: February 2023

Gastrointestinal parasites are a significant challenge in sheep farming, and periparturient ewes are one of the most susceptible categories in sheep flocks. This study aimed to verify whether the injection of B vitamins at the acupuncture point governing vessel 14 (GV14) can influence the parasitic load or host parasite interaction in naturally infected ewes during the peripartum period. Four weeks before parturition, 25 ewes were divided into five treatment groups: (1) Dose Control: 0.2 mL of B complex via IM; (2) Drug Control: 2 mL Complex B via IM; (3) Acupoint Control: 0.2 mL of Water at GV14 point; (4) Control; (5) Test group: 0.2 mL of B complex at the GV14 point. Treatments were performed at weeks -3, -1, 2, 4, and 6 about the parturition time. Fecal samples to estimate the parasitic load by fecal egg counts (FEC) and total blood samples for hemogram examination were performed seven days after the treatment, coinciding with weeks -2, 3, 5, and 7 about the parturition time. The number of peripheral eosinophils was higher in group 3 than in group 1 (p <0.05). Although groups 3 and 5 had lower mean values of FEC and higher hematological values at the time of weaning, these differences were not statistically significant (p> 0.05) according to the F test. However, all animals in groups 3 and 5 maintained low parasitism levels until the end of the experiment. Further studies should be performed with larger sample sizes and minor changes to the experimental protocol to elucidate the role of GV14 acupoint stimulation in the host-parasite relationship.
Perspectives on Malay Language Use and Autonym Preference Among Urban Malays in South Thailand
Authors: Joll Christopher M. , Aree Srawut
Published: January 2023

This article offers theoretical and ethnographic perspectives on language ideology and autonym preference among bi-lingual urban Malays in Pattani’s provincial capital. The first of its two substantive sections presents a concise summary of the most relevant insights provided by linguistic anthropologists and sociolinguists who have written on language ideology and the role of language in identity formation. The primary purpose of the second section is to explore the heuristic utility of these theoretical insights on a range of ethnographic vignettes where a range of language-related issues have historically represented a significant source of mistrust between the local Malay majority and Bangkok. We develop insights provided by interactionalist perspectives on language and identity formation to Malay identity formation, specifically which autonyms are strategically adopted.
Morphological and phylogenetic study of Acanthosquilla Manning, 1963 (Stomatopoda: Nannosquillidae) mantis shrimps, with description of two new species from the Ryukyu Islands, Japan
Authors: NAKAJIMA HIROKI , REIMER JAMES DAVIS , NARUSE TOHRU
Published: January 2023

Three species of nannosquillid mantis shrimps, including two new species, Acanthosquilla ryukyuensis n. sp. and Acanthosquilla shoheii n. sp., are described based on specimens collected from the Ryukyu Islands, Japan. The two new species resemble A. derijardi Manning, 1970, but can be distinguished from A. derijardi by the following features: 1) rostral plate anterolateral corner forms almost a right angle; 2) the distal tip of the antennular somite dorsal process reaches or slightly falls short of proximal half of rostral plate; and 3) eighth thoracic somite (= TS8) posterior margin is black medially. Furthermore, A. ryukyuensis n. sp. and A. shoheii n. sp. are easy to identify by the bifurcated lateral tooth of the telson, and by the posterodorsal pattern of the telson, respectively. In this study, molecular analyses based on partial sequences of mitochondrial 12S and 16S ribosomal DNA, cytochrome oxidase subunit I (COI), and the partial nuclear gene of 28S ribosomal DNA recovers these three species of Acanthosquilla and A. multifasciata (Wood-Mason, 1895) (the type species of the genus) in a single clade. The resulting trees also suggest the polyphyly of Nannosquillidae but with low nodal support. Detailed examinations of the morphological and color features and DNA barcoding results allowed us to delineate intraspecific variations and interspecific differences. The number and shape of setae under the dorsal spine of raptorial claw carpus was found to be useful in distinguishing A. shoheii n. sp. from A. derijardi and A. ryukyuensis n. sp., while combinations of the coloration of the rostral plate, posterior margin of TS8 and posterodorsal surface of telson are useful to distinguish the three species.
Description of three new species of Myrmeleon Linnaeus, 1767 from West Africa (Neuroptera: Myrmeleontidae)
Authors: MICHEL BRUNO , AKOUDJIN MASSOUROUDINI
Published: January 2023

Three antlion species, Myrmeleon croceus n. sp., Myrmeleon foucarti n. sp. and Myrmeleon nemoleontoides n. sp. from West Africa are described and illustrated. Information on their distribution, ecology and predators is provided.
The genus Holaptilon Beier, 1964: discussion on the poorly known boxer mantis genus, with a new species (Mantodea, Gonypetidae) 
Authors: YILMAZ KAAN , SEVGİLİ HASAN
Published: January 2023

The boxer mantis genus Holaptilon Beier, 1964 (Mantodea: Gonypetidae: Gonypetinae) is known to include two flightless species with a similar body size and morphology. Type species of the genus, H. pusillulum Beier, 1964, is reported from Israel and Jordan. An interesting species of the genus was recently identified from Iran (H. brevipugilis Kolnegari, 2018). In this research, a new species of H. yagmur Yılmaz & Sevgili sp. n. is described from Turkey. This new species was collected from Karacadağ (Şanlıurfa), a volcanic mountain in the Southeastern Anatolia region. Its typical habitat is steppic stony areas. It indicates that the species may be cryptic or nocturnal since it was collected from under stones and ground traps. This finding indicates that the genus is more widespread than previously known and may have more species yet to be discovered. The existence of the genus Holaptilon was reported for the first time in Turkey. Meanwhile, while reviewing the praying mantis list of Turkey, we determined that the samples collected from Ağrı, which are given in the Mantodea list of Turkey, were misdiagnosed as Armene robusta Mishchenko, 1956 and actually belong to the genus Holaptilon, and that Turkey currently hosts 20 praying mantis species/subspecies.
Bone Marrow Mesenchymal Stem Cells (BMSC) from Exosome with High miR-184 Level Ameliorates Sepsis
Authors: Guo Zhongdong , Yi Shijie
Published: February 2023

This study assesses whether BMSC from exosome with high miR-184 level ameliorates sepsis. BMSC with high miR-184 expression established. RAW264.7 cells were cultivatedin vitroand divided into control set, model set, BMSC set and BMSC with high miR-184 level set. The model was established through infection of RAW264.7 cells with LPS followed by analysis of cell proliferation and apoptosis, activity of ROS and SOD, secretion of IL-1β, IL-6 and TNF-αas well as the expression of NF-κB and TRAIL. BMSC set showed significantly upregulated miR-184 expression, increased cell proliferation and SOD activity, reduced ROS activity, decreased secretion of IL-1β, IL-6 and TNF-αas well as the expression of NF-κB and TRAIL. The above changes were more significant in the set of BMSC with overexpression of miR-184. In conclusion, cell proliferation, apoptosis and inflammation in RAW264.7 cells induced with LPS is regulated by BMSC from exosome with high expression of miR-184, which is possibly through restraining the NF-κB and TRAIL and oxidative stress.
Smart optical fiber fabric based on side-emitting and side-coupling for pulse and blood oxygen measurement
Authors: Zhang Meiling , Su Huiying , Zhang Cheng , Sun Zheng , Jiang Zhen
Published: February 2023

Monitoring pulse and arterial oxygen saturation (SpO2) continuously and in real-time is conducive to the prevention and monitoring of cardiovascular disease. The reported optical fiber fabrics have the shortcomings of low side-emitting and side-coupling efficiency of a single fiber, and more optical fibers were used. In this paper, we propose a micro-bending bulge structure based on side-emitting and side-coupling of the polymer optical fiber (POF), and a small number of the POFs are woven into the fabric as weft yarns to measure pulse and SpO2 using a simple plain weave. The experiments investigated the effect of the different micro-bending bulge structures on the side-emitting and side-coupling efficiencies by means of the ray tracing method, explored the feasibility to measure pulse waves and SpO2 on the fingertip, brachial artery, and forehead ophryon, and evaluated the accuracy of the measurements in the static, dynamic, and sweating states. The results show that the side-emitting and side-coupling efficiencies of the POF are optimal by adopting a 1 mm micro-bending bulge height and a 3 mm micro-bending bulge width. The fabric sensor with three side-emitting POFs and two side-coupling POFs is capable of monitoring pulse and SpO2 on the forehead. In addition, the maximum error is 1 bpm for the pulse and within 2% for SpO2 on the forehead.
“Your English is Good for an Immigrant”: Examining Mixed Effects of Mindset Messages on Perceived Linguistic Potential of and Blame Attributions Towards ESL Migrants
Authors: Lou Nigel Mantou , Noels Kimberly A.
Published: February 2023

Social exclusion can exacerbate newcomers’ language difficulties and undermine their social integration. We examined whether language mindsets induce mixed attitudes towards migrants with limited proficiency in the target language, and indirectly affect willingness to interact with migrants and attitudes toward migrants’ language education. Across two pre-registered experiments ( N = 531) conducted in Canada, we found that people who were primed with fixed (vs. growth or control) mindsets tended to believe migrants have less potential to improve their English, but were less likely to blame them for their lack of improvement (“not their fault if they can't improve”), suggesting fixed mindsets contribute to mixed attitudes toward migrants. Furthermore, perceived linguistic potential was negatively and blame was positively correlated with contact avoidance and opposition to publicly funded language education for newcomers. These effects held after controlling for political orientations and perceived fluency of the target speaker, suggesting that language mindsets contribute to language judgments that could impact migrants’ acculturation experiences.
Understanding and Improving Older People’s Well-Being through Social Prescribing Involving the Cultural Sector: Interviews from a Realist Evaluation
Authors: Gorenberg Jordan , Tierney Stephanie , Wong Geoff , Turk Amadea , Libert Sebastien , Potter Caroline , Eccles Kathryn , Forster Shona , Husk Kerryn , Chatterjee Helen J. , Webster Emma , McDougall Beth , Warburton Harriet , Shaw Lucy , Mahtani Kamal R.
Published: February 2023

Social prescribing is a non-clinical approach to addressing social, environmental, and economic factors affecting how people feel physical and/or emotionally. It involves connecting people to “community assets” (e.g., local groups, organizations, and charities) that can contribute to positive well-being. We sought to explain in what ways, for whom, and why the cultural sector can support social prescribing with older people. We conducted semi-structured interviews with 28 older people (aged 60+) and 25 cultural sector staff. The following nine concepts, developed from interview data, progressed the understanding of tailoring cultural offers, which came from our previous realist review— immersion, buddying, café culture, capacity, emotional involvement, perseverance, autonomy, elitism, and virtual cultural offers. Through tailoring, we propose that older people might experience one or more of the following benefits from engaging with a cultural offer as part of social prescribing—being immersed, psychological holding, connecting, and transforming through self-growth.
Clientelism, partisanship, and ideology
Authors: Arslantaş Düzgün , Arslantaş Şenol
Published: January 2023

This paper aims to highlight the role of clientelism in the Justice and Development Party's (Adalet ve Kalkınma Partisi) electoral dominance in Turkish politics. Based on intensive fieldwork in Istanbul's one of the poorest and conservative districts of Bağcılar, it argues that the expansion of clientelist networks under the Adalet ve Kalkınma Partisi government has twofold ramifications, which in turn have reproduced the cycle of dominance. First, it strengthened clients’ partisan identification. Second, it changed clients’ ideology such that they became less resistant to or even supportive of neoliberal reforms that extensively undermined their well-being.
Citrobacter keratitis: predisposing factors and clinical characteristics
Authors: Soleimani Mohammad , Masoumi Ahmad , Tabatabaei Seyed Ali , Zamani Mohammad Hossein
Published: January 2023

Purpose

To report predisposing factors, clinical presentation, antibiotic sensitivity, and management of Citrobacter-caused infectious keratitis.

Methods

We retrospectively reviewed the medical records of culture-proven cases of Citrobacter keratitis in a tertiary referral center for 8 years (from January 2012 to September 2020). Demographic data of the patients, predisposing factors, and presenting signs were extracted.

Results

Eighteen cases of microbial keratitis due to Citrobacter spp. were identified. The median age of the patients was 66 years (range: 10–89, interquartile range : 59–81). Thirteen patients were male and 5 were female. Multiple predisposing factors were identified in all eyes, including ocular surface disease (n = 8), previous corneal surgery (n = 6), and history of ocular trauma (n = 6). Five patients were diabetic. Corrected distance visual acuity (CDVA) of patients was light perception (LP) in 8 patients, hand motion (HM) in 7, counting fingers (CF) at 1 m in 1, and CF at 2 m in 2 patients. Thirteen eyes exhibited hypopyon. An area of corneal thinning was observed in 7 eyes (38.9%). Endophthalmitis due to infectious keratitis developed in one patient. In vitro susceptibility testing confirmed high sensitivity to ceftazidime and aminoglycosides. Medical management consisted primarily of topical amikacin (20 mg/ml) combined with topical cefazoline (50 mg/ml) (72.2%). Surgical tectonic procedures were carried out in 7 eyes (38.9%).

Conclusion

Citrobacter spp. is a rare cause of bacterial keratitis.Previous keratoplasty and ocular surface problems are important risk factors. The prognosis is not good and surgical tectonic intervention is required in many cases to resolve the corneal infection.
In it for the long run: perspectives on exploiting long-read sequencing in livestock for population scale studies of structural variants
Authors: Nguyen Tuan V. , Vander Jagt Christy J. , Wang Jianghui , Daetwyler Hans D. , Xiang Ruidong , Goddard Michael E. , Nguyen Loan T. , Ross Elizabeth M. , Hayes Ben J. , Chamberlain Amanda J. , MacLeod Iona M.
Published: January 2023

Studies have demonstrated that structural variants (SV) play a substantial role in the evolution of species and have an impact on Mendelian traits in the genome. However, unlike small variants (< 50 bp), it has been challenging to accurately identify and genotype SV at the population scale using short-read sequencing. Long-read sequencing technologies are becoming competitively priced and can address several of the disadvantages of short-read sequencing for the discovery and genotyping of SV. In livestock species, analysis of SV at the population scale still faces challenges due to the lack of resources, high costs, technological barriers, and computational limitations. In this review, we summarize recent progress in the characterization of SV in the major livestock species, the obstacles that still need to be overcome, as well as the future directions in this growing field. It seems timely that research communities pool resources to build global population-scale long-read sequencing consortiums for the major livestock species for which the application of genomic tools has become cost-effective.
Whole exome sequencing with a focus on cardiac disease-associated genes in families of sudden unexplained deaths in Yunnan, southwest of China
Authors: Wei Si-Jie , Du Jin-Liang , Wang Yue-Bing , Qu Peng-Fei , Ma Lin , Sun Zhong-Chun , Tang Xue , Liu Kai , Xi Yan-Mei , Nie Sheng-Jie , Jia Peng-Lin , Long Wu , Qu Yong-Qiang , Li Yu-Hua , Lei Pu-Ping
Published: January 2023

Objectives

To explore the causes of sudden unexpected death (SUD) and to search for high-risk people, whole exome sequencing (WES) was performed in families with SUDs. 

Methods

Whole exome sequencing of 25 people from 14 SUD families were screened based on cardiac disease-associated gene variants, and their echocardiograms and electrocardiograms (ECG) were also examined. The protein function of mutated genes was predicted by SIFT, PolyPhen2 and Mutation Assessor.

Results

In the group of 25 people from 14 SUD families, 49 single nucleotide variants (SNVs) of cardiac disease-associated genes were found and verified by Sanger sequencing. 29 SNVs of 14 cardiac disorder-related genes were predicted as pathogens by software. Among them, 7 SNVs carried by two or more members were found in 5 families, including SCN5A (c.3577C > T), IRX4 (c.230A > G), LDB3 (c.2104 T > G), MYH6 (c.3G > A), MYH6 (c.3928 T > C), TTN (c.80987C > T) and TTN (c.8069C > T). 25 ECGs were collected. In summary, 4 people had J-point elevation, 2 people had long QT syndrome (LQTS), 4 people had prolonged QT interval, 3 people had T-wave changes, 3 people had sinus tachycardia, 4 people had sinus bradycardia, 4 people had left side of QRS electrical axis, and 3 people had P wave broadening. Echocardiographic results showed that 1 person had atrial septal defect, 1 person had tricuspid regurgitation, and 2 people had left ventricular diastolic dysfunction.

Conclusions

Of the 14 heart disease-associated genes in 14 SUDs families, there are 7 possible pathological SNVS may be associated with SUDs. Our results indicate that people with ECG abnormalities, such as prolonged QT interval, ST segment changes, T-wave change and carrying the above 7 SNVs, should be the focus of prevention of sudden death.
Integrated single-molecule real-time sequencing and RNA sequencing reveal the molecular mechanisms of salt tolerance in a novel synthesized polyploid genetic bridge between maize and its wild relatives
Authors: Li Xiaofeng , Wang Xingyu , Ma Qiangqiang , Zhong Yunfeng , Zhang Yibo , Zhang Ping , Li Yingzheng , He Ruyu , Zhou Yang , Li Yang , Cheng Mingjun , Yan Xu , Li Yan , He Jianmei , Iqbal Muhammad Zafar , Rong Tingzhao , Tang Qilin
Published: January 2023

Background

Tripsacum dactyloides (2n = 4x = 72) and Zea perennis (2n = 4x = 40) are tertiary gene pools of Zea mays L. and exhibit many abiotic adaptations absent in modern maize, especially salt tolerance. A previously reported allopolyploid (hereafter referred to as MTP, 2n = 74) synthesized using Zea mays, Tripsacum dactyloides, and Zea perennis has even stronger salt tolerance than Z. perennis and T. dactyloides. This allopolyploid will be a powerful genetic bridge for the genetic improvement of maize. However, the molecular mechanisms underlying its salt tolerance, as well as the key genes involved in regulating its salt tolerance, remain unclear.

Results

Single-molecule real-time sequencing and RNA sequencing were used to identify the genes involved in salt tolerance and reveal the underlying molecular mechanisms. Based on the SMRT-seq results, we obtained 227,375 reference unigenes with an average length of 2300 bp; most of the unigenes were annotated to Z. mays sequences (76.5%) in the NR database. Moreover, a total of 484 and 1053 differentially expressed genes (DEGs) were identified in the leaves and roots, respectively. Functional enrichment analysis of DEGs revealed that multiple pathways responded to salt stress, including “Flavonoid biosynthesis,” “Oxidoreductase activity,” and “Plant hormone signal transduction” in the leaves and roots, and “Iron ion binding,” “Acetyl-CoA carboxylase activity,” and “Serine-type carboxypeptidase activity” in the roots. Transcription factors, such as those in the WRKY, B3-ARF, and bHLH families, and cytokinin negatively regulators negatively regulated the salt stress response. According to the results of the short time series-expression miner analysis, proteins involved in “Spliceosome” and “MAPK signal pathway” dynamically responded to salt stress as salinity changed. Protein–protein interaction analysis revealed that heat shock proteins play a role in the large interaction network regulating salt tolerance.

Conclusions

Our results reveal the molecular mechanism underlying the regulation of MTP in the response to salt stress and abundant salt-tolerance-related unigenes. These findings will aid the retrieval of lost alleles in modern maize and provide a new approach for using T. dactyloides and Z. perennis to improve maize.