bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluation of School Health Status, Explanatory Study
Authors:   Umm Al-Qura University, Bushara Mohamed Osman Elamin
Published: December 2020

Background: Schools are one of the best settings-based approach to promote health. Schools remain for many years been recognized as an important settings for health promotion for the community. The study provides description of schools health status in the city, concerning the activities and services components of school health and the deficiencies, accordingly the requested procedures and processes to improve that health situation, assuming that improvement of schools health status will lead the improvement of health status of the overall community. Objectives: The study aims to assess schools health status in Makkah city. Introduction: The study conducted to evaluate schools health status and services provided in Makkah city, 20 schools selected randomly for this purpose. Methodology: Descriptive study had been implemented, simple random sampling used, (20) schools selected for the evaluation of the six components of school health services and activities, data collected through checklist and interviews. Results: The study clarified that most schools in Makkah have a health supervisor, health supervision plan and a committee, but only 32% of schools have healthy foods provided. Conclusion: The study concluded that, health supervision was active, but there were weaknesses in the food services, unhealthy foods and drinks were available in schools. Recommendations: The study recommends for motivating schools health supervisors for the extra efforts they are providing beside their teaching responsibilities, in addition to that, periodic health education sessions for students is requested to raise their awareness on different health risks especially in school environment.
Feminist Öznenin Toplumsalla Kuruluşunda Sinema-Ötekiyle Karşılaşma
Authors: ELPEZE ERGEÇ Nüket
Published: December 2020

Bu çalışma, Türkiye’de “mahcup feminizm” kavramı ekseninde 1980’li yılların akademik feminist düşüncesinin sinemaya etkisine bakmayı amaçlayan bir girişimdir. Güçlü bir feminist sesin olmadığı bu yıllar, akademide kadın sorunun araştırıldığı yıllardır. Aynı yıllar sinemanın da değişim geçirdiği yıllardır. Özellikle kadınlara ve kadınlığa ilişkin meselelerin ele alındığı kadın filmleri kategorisi oluşmaya başlaması da bu döneme denk gelir. Feminist söylem çözümlemesi metnin içinde doğallaşarak görünmezleşmiş olan ve kendini metin aracılığıyla yeniden üreten her türlü ideolojiyi ortaya çıkarır. Çalışmanın kavramsal çerçevesi Türkiye’deki feminist hareketin öncüllerinden Şirin Tekeli’nin güçlü bir feminist sesin olmamasını tanımlamakta kullandığı “mahcup feminizm” terimi merkezinde oluşturulmuştur. Kavramsal çerçeve kurulurken dikkat edilen nokta fail olan öznenin değişimi dönüşümü ve kendini kurma biçimi olmuştur. Akademide Şirin Tekeli, Bir Yudum Sevgi filmindeki Aygül, Videosinema dergisinde karşılaşılan Şengül’ün söylem düzeni içinde feminist özne olma biçimleri incelenmiştir. Çalışmada akademik yazın, popüler yazın ile sinema arasındaki kadın kimliğine ilişkin öznelerin karşılaşmaları, kucaklaşmaları, benzerlikler ve sınırlamaları saptanmış ve tartışılmıştır.
Faces and Surfaces in the Landscape of Pasolini’s ‘Palestina’
Authors: BAYSAN SERİM Işıl
Published: December 2020

Hardly known that Pier Paolo Pasolini has created a landscape trilogy through the location-hunting documentaries in his oeuvre. The first of these works is also the one that comprises the spine of this essay, Sopraluoghi in Palestina (Locations in Palestine, 1963), the second one is Appunti per un film sull'India (Notes for a Film on India, 1968), and finally, in Per un'orestiade africana (Notes for an African Oresteia, 1969/70). The use of historically and culturally layered landscapes from varying perspectives makes his documentaries a ”territorial assemblage” in which any number of things or pieces of things has gathered. Following the footprints of Pier Paolo Pasolini, this study aims to explore the film, namely Sopraluoghi in Palestina (Locations in Palestine, 1963) and to present different articulation of space, landscape, territory and place. Particularly, the narrative information, pure observation and his self-experience of landscape are spliced together in mythical as well as historical shots which have been incandescently defined by his poetic realism. Film, indeed, not only does enable to mediate some Deleuzoguattarian concepts penetrating from philosophy to cinema, but also does open new paths for ”thinking differently” on the complexity of space. This article, by delving into the real-time shots of the film will problematize the spatial-temporal dimensions are involved in the cartography formed by heterogeneous forces or/and multiplicities defined by ”zones of indiscernibility” in the landscape. In this way, I target to reveal its diagrammatic formation which provide the viewer thinking through words and images, nature and culture, faces and surfaces.
Bir Kara Kaplumbağasının Karapaksındaki Kırık Olgusu
Authors: Polat Eren , Coşkun Sinem , Can Ümit Koray , Kayapınar Sema Dilan , Yıldırım Onur
Published: December 2020

Bu olgu sunumunda, bir kara kaplumbağasının üst kabuğundaki kırık olgusu konu edildi. Kaplumbağanın yapılan muayeneleri sonucunda, nöral ve kostal plakları arasında longitudinal yönde bir kırık olduğu tespit edildi. Bununla birlikte, kostal ve marjinal plaklar üzerinde transversal doğrultuda ikinci bir kırık hattının daha olduğu görüldü. Radyografik muayenede, ikinci kırık hattının nöral plaklar üzerinden geçerek kaplumbağanın sağ tarafına doğru devam ettiği tespit edildi. Bu iki kırık hattı ortopedik pin ve teller kullanılarak operasyon ile sabitlendi. Yapılan bu operasyon ve postoperatif bakımın ardından sağlığına kavuşan kaplumbağa doğal ortamına bırakıldı. Sonuç olarak, nadiren karşılaşılan karapaks kırıklarının tanı ve tedavileri hakkında meslektaşlarımıza bilgi vermek amaçlandı.
Koroner Arter Hastalığı olan Köpeklerde Hipertansiyonun İnflamatuar Etkisinin Ekokardiyografi ile Değerlendirilmesi
Authors: İriadam Mehmet , Toker Melahat
Published: December 2020

Bu çalışma; koroner arter hastalığı (KAH) bulunan köpeklerde hipertansiyonun oluşturduğu (HT) inflamatuvar süreci üzerine olası etkilerini belirlemek üzere yapılmıştır. Ankara ilindeki özel pet kliniklerine gelen, farklı yaş, kilo, cins ve ırklardaki toplam 25 köpek üzerinde yürütüldü. Hayvanlara elektrokardiyografi, tansiyon, telegrafi, tam kan ve C- reaktif protein (CRP) ölçümleri yapıldı. Ekokardiyografilerinde ise 2D, M-mod, ve renkli Doppler ekokardiyografi yöntemleri kullanılarak, sol ventrikül sistol ve diyastol çapları, ventrikül duvar kalınlıkları, ventrikül duvar hareketlerindeki anormallikler ile kapak patolojileri değerlendirildi. Hayvanların ekokardiyografilerinde sol ventrikül konsantrik hipertrofi (LVH) ve diastolik diskfonksiyonu tespit edildi. Ayrıca; Ekokardiyografide Mitral kapak tutulumları ile kapakçıklar üzerinde anüler kalsifikasyon izlendi. İnterventriküler septum kalınlığında önemli ölçüdeki artışlarla beraber sol ventrikül arka duvar kalınlığında bir artış belirlendi. Bununla birlikte; yüksek olan CRP ve kolestrol değerlerinde ise anlamlı bir artış belirlendi. Yapılan rutin ekokardiyografilerde parasternal uzun eksende M mode tekniği ile sol ventrikül diastolik ve sistolik çapları (cm), interventriküler septum çapı (cm), posterior duvar kalınlığı (cm), ejeksiyon fraksiyon (%), fraksiyon kısalma (%), aort çapı (cm) ve sol atriyum(cm) ölçüldü. Parasternal kısa eksende mitral kapağın yapısı, segmenter duvar hareket bozukluğu, pulmoner arter çapı ve pulmoner kapak değerlendirildi. Apikal boşluklarda 2,3,4 ve 5 boşlukları atriyoventriküler kapakları (mitral-triküspit kapak) ve semilunar kapak (aort kapak) değerlendirildi. İnflamasyonun sürecinin artışı, damarlarda oluşan kolestrol plaklarını da tetikleyebileceği ya/ya da daha fazla pıhtı yaratabileceği şeklindedir. Hipertansiyonun kardiyovasküler hastalıklar için önemli risk faktörlerinden hem morbidite hem de mortaliteyi önemli ölçüde arttırdığı şeklinde düşünülmektedir. Bütün bu değerlendirmelerimiz de ekokardiyografi, sol ventrikül hipertansiyonun tanısında elektrokardiyografinin yanı sıra vazgeçilemez bir tanı yöntemi olarak karşımıza çıkmaktadır.
From the ecocalypse to the infocalypse: The importance of building a new culture of protecting the infosphere
Authors: Ho Tung Manh
Published: December 2020

In this essay, we reflect on the importance of building a new culture that protects the infosphere. We also discuss the parallels between the ecosphere and the infosphere.
The Development of Digital Economy in Indonesia
Authors: Intansari Rosa Kusnia
Published: December 2020

Pesatnya perkembangan teknologi digital di Indonesia mendukung perkembangan aktivitas perusahaan berbasis teknologi dan digital untuk mengembangkan bisnis start up, industri kreatif, UMKM dan lembaga pendidikan yang bergerak di bidang informasi teknologi. Pelaku jasa keuangan konvensional dan teknologi keuangan nasional perlu membangun kolaborasi yang didorong oleh keberadaan pemerintah sebagai penyedia layanan teknologi keuangan untuk meningkatkan pemerataan akses, memajukan industri keuangan agar lebih efisien dalam menopang modal dan kegiatan produksi UMKM serta meningkatkan pertumbuhan ekonomi Indonesia. Faktanya, sejumlah perusahaan besar berbasis teknologi bekerjasama baik dengan bank untuk perihal sumber daya investasi. Beberapa pengaruh perkembangan teknologi digital adalah adanya internet yang mendorong pertumbuhan ekonomi, pendapatan per kapita Indonesia di tengah-tengah ekonomi global yang menurun karena adanya persaingan harga minyak di pasar internasional yang semakin meningkat memperluas kesempatan kerja serta meningkatkan fasilitas publik. Contohnya penggunaan kartu kredit dan kartu ATM yang menjadi pilihan pembayaran dalam transaksi online maupun offline. E-money juga menjadi salah satu peningkatan teknologi digital dalam hal alat pembayaran. E-money mengalami pertumbuhan pesat sejak dulu dalam hal jumlah transaksi, nilai transaksi, dll. Bahkan pemerintah mewajibkan pengguna jalan melakukan pembayaran menggunakan e-money. Teknologi digital membuat kegiatan menjadi lebih efisien dan memungkinkan lalu lintas informasi menyebar lebih cepat dibagikan dengan orang lain.
NHÀ VĂN HÓA TRONG ĐỜI SỐNG NÔNG THÔN VIỆT NAM
Authors: AISDL
Published: December 2020

NHÀ VĂN HÓA TRONG ĐỜI SỐNG NÔNG THÔN VIỆT NAMNGUYỄN THỊ THÚY NGÂNKHÓA LUẬN TỐT NGHIỆP NGÀNH VIỆT NAM HỌCKHOA VIỆT NAM HỌC VÀ TIẾNG VIỆTTRƯỜNG ĐẠI HỌC KHOA HỌC XÃ HỘI VÀ NHÂN VĂNĐẠI HỌC QUỐC GIA HÀ NỘI - 2016
FGF12 is differentially expressed in the brain metastases of patients with metastatic breast cancer.
Authors: Mamoor Shahan
Published: December 2020

Metastasis to the brain is a clinical problem in patients with breast cancer (1-3). We mined published microarray data (4, 5) to compare primary and metastatic tumor transcriptomes to discover genes associated with brain metastasis in patients with metastatic breast cancer. We found that the fibroblast growth factor 12, encoded by FGF12, was among the genes whose expression was most different in the brain metastases of patients with metastatic breast cancer as compared to normal breast tissues. FGF12 mRNA expression was significantly higher in brain metastatic tissues as compared to primary tumors of the breast. Up-regulation of FGF12 expression may contribute to metastasis of tumor cells from the breast to the brain in humans with metastatic breast cancer.
Variabel dan Skala Pengukuran Statistik
Authors: Janna Nilda Miftahul
Published: December 2020

Setelah merumuskan rumusan masalah, mengukur variabel dalam kerangka teorimerupakan bagian integral dari penelitian yang merupakan aspek penting dari desainpenelitian. Objek yang secara fisik dapat diukur dengan beberapa instrumen yangdikaliborasi tidak menimbulkan masalah pengukuran. Skala pengukuran digunakan untukmenentukan panjang pendeknya interval yang ada dalam satuan alat ukur. Denganmenggunakan skala pengukuran, maka alat ukur yang digunakan akan menghasilkan datakuantitatif
Exorcising the “Ghosts” from the Government Payroll in Developing Countries in the Wake of the Covid-19 Pandemic: Ghana’s Empirical Example
Authors: Quarm Richmond Sam , Sam-Quarm Rosemond , Sam-Quarms Richmond
Published: December 2020

The salary payment of government workers constitute a significant percentage of total government expenditure in developing economies, simply because the government remains the largest or biggest employer. The Government Payroll system, therefore, requires a robust control mechanism to detect and prevent the occurrence of “payroll fraud”, as the irregularity denies the state of huge sums of monies going down the drain and into private pockets, and which could have otherwise been channelled into some critical sectors of the economy; and to minimise the excessive borrowing by government to fill the gap. The several efforts and reforms by the Controller and Accountant-General’s Department (CAGD) and the Ghana Audit Service (GAS) in particular; and the Ministry of Finance (MoF) in general, to clean the Government Payroll of these “payroll frauds” consistently over the years have not yielded the desired results. The various studies conducted on “payroll fraud” in Ghana did not address themselves to the introduction of the “Electronic-Salary Payment Voucher (E-SPV) system since 2014, which was hailed by many as the final panacea to the “annual ritual of ghost workers on the government payroll”. To fill the gap, we conducted this empirical cross-sectional research on “payroll fraud” based on the “fraud triangle theory” and the “graft estimation model”. We employed non probability purposive, but convenient, sampling methodology by means of structured questionnaires and face-to-face interviews to arrive at our conclusion. Our major finding was that “payroll fraud” can never be eliminated (but only minimised), and must therefore be treated and necessarily managed to the barest minimum (between 1% and 5%), just as normal “bad debts” in Financial Statements. Policy makers will have to revisit the issues about “Ghost Workers”, in the midst of the novel and dreaded, and disastrous Convid-19 pandemic.
Pentingnya Materi Lingkungan Terhadap Pembelajaran Bahasa Indonesia
Authors: Luthfiana Anisa
Published: December 2020

Berdasarkan hasil penelitian diatas, maka dapat disimpulkan bahwa materi lingkungan sangat penting, khususnya pada pembelajaran bahasa Indonesia. Oleh karena itu, dengan adanya materi lingkungan, peserta didik akan lebih menjaga dan melestarikan lingkungan sekitarnya. Materi lingkungan juga memberikan dampak pada perilaku peserta didik, dengan adanya materi lingkungan ini peserta didik juga lebih peka terhadap kondisi lingkungan, membangun individu peserta didik yang jujur, disiplin, optimis, empati, dan religius. Tulisan ini bertujuan agar masyarakat dan peserta didik dapat menjaga dan melestarikan lingkungan.
The role of gender on the effects of Indonesian manpower skills on their competition readiness/preparedness
Authors: AISDL
Published: December 2020

The Asean economic community requires high economic competition among ASEAN countries. Indonesia is one of the ASEAN Countries which is assumed to have a low capacity to win the competition. Hence, Indonesian workers are sued to have a better skill level heading the tight competition. Thus, workers with better skills are needed to strengthen the comptetition. Both practition and scholars believe that the issues of gender are currently attractive for the manpower market. Accordingly, this study is aimed to explore the effects of gender on the influence of skill on the readiness of Indonesia worker toward business competition in the Asean Economic Community (AEC). This study employs 352 workers from various Industries. Multiple regressions are used to analyze the data. The result shows that the skill of male workers has stronger effect on their readiness toward AEC competition rather than their counterparts. Implication and future research are discussed.
“Kinh tế Việt Nam - Thăng trầm và đột phá” - VTV Giới thiệu sách
Authors: AISDL
Published: December 2020

Không thể không tự hỏi, sự phát triển trong hơn 20 năm Đổi Mới của Việt Nam nằm ở đâu trong lịch sử của dân tộc, của nền kinh tế toàn cầu đương đại và của số phận nhân loại? Có lẽ, không một ai, với sự tâm huyết dành cho dân tộc Việt Nam, sự trăn trở và những nỗ lực của người Việt Nam, lại không thấy được nỗi truân chuyên của một hành trình đầy thăng trầm, những bước đột phá và cả những bài học sâu sắc, không chỉ dành cho nhận thức lịch sử, mà còn có cả ý nghĩa hướng tới giải pháp tương lai.
Emotional AI and Freedom of Thought
Authors: Ho Tung Manh
Published: December 2020

In this essay, I reflect on five ways emotional AI technologies interfere with our freedom of thought.
Contingency Theory and Mediating Effect within Work Life
Authors: syam muhammad alvin arkananta
Published: December 2020

artikel ini bertujuan untuk menjelaskan tentang apa itu Contingency Theory dan Mediating Effect, kenapa kedua hal tersebut sering dipakai oleh perusahaan dalam hal memecahkan masalah, dan yang lain-lain. semua akan dijelaskan di artikel ini
Bevacizumab treatment of patients with breast cancer is associated with differential expression and up-regulation of C10orf10.
Authors: Mamoor Shahan
Published: December 2020

Bevacizumab (Avastin) is an approved treatment option by the European Medicines Agency (1) for more than a quarter billion women in the European Union, and despite having its indication withdrawn by the Food and Drug Administration in 2011 is still utilized in clinical trials in the United States (2, 3). We mined published microarray data (4) from the PROMIX trial to understand in an unbiased fashion genes most transcriptionally perturbed by bevacizumab administration and how this interacted with a standard anthracycline and taxane chemotherapeutic regimen, epirubicin and docetaxel; we integrated these findings with analysis of findings from a separate microarray dataset generated using bevacizumab administration in an experimental model of endometrial cancer (5). We report here the differential and increased expression of open reading frame 10 on chromosome 10, encoded by C10orf10 in the primary tumors of women treated with bevacizumab for breast cancer.
GRM8 is differentially expressed in the brain metastases of patients with metastatic breast cancer.
Authors: Mamoor Shahan
Published: December 2020

Metastasis to the brain is a clinical problem in patients with breast cancer (1-3). We mined published microarray data (4, 5) to compare primary and metastatic tumor transcriptomes to discover genes associated with brain metastasis in patients with metastatic breast cancer. We found that the glutamate metabotropic receptor 8, encoded by GRM8, was among the genes whose expression was most different in the brain metastases of patients with metastatic breast cancer as compared to normal breast tissues and primary tumors of the breast. GRM8 mRNA was present at increased quantities in brain metastatic tissues as compared to primary tumors of the breast and to normal breast tissues. Up-regulation of GRM8 expression may contribute to metastasis of tumor cells from the breast to the brain in humans with metastatic breast cancer.
LYVE1 is differentially expressed in the lymph node and brain metastases of patients with metastatic breast cancer.
Authors: Mamoor Shahan
Published: December 2020

Metastasis to the brain is a clinical problem in patients with breast cancer (1-3). We mined published microarray data (4, 5) to compare primary and metastatic tumor transcriptomes to discover genes associated with brain metastasis in patients with metastatic breast cancer. We found that lymphatic vessel endothelial hyaluronan receptor 1, encoded by LYVE1, was among the genes whose expression was most different in the brain and lymph node metastases of patients with metastatic breast cancer as compared to normal breast tissues. LYVE1 mRNA was present at significantly reduced quantities in brain metastatic tissues as compared to normal breast tissues. These data combined suggest some level of common origin for metastases that reside in the lymph nodes and colonize the brain.
Nebulin is differentially expressed in the brain metastases of patients with metastatic breast cancer.
Authors: Mamoor Shahan
Published: December 2020

Metastasis to the brain is a clinical problem in patients with breast cancer (1-3). We mined published microarray data (4, 5) to compare primary and metastatic tumor transcriptomes to discover genes associated with brain metastasis in patients with metastatic breast cancer. We found that nebulin, encoded by NEB, was among the genes whose expression was most different in the brain metastases of patients with metastatic breast cancer as compared to normal breast tissues. NEB mRNA was present at increased quantities in brain metastatic tissues as compared to primary tumors of the breast. Up-regulation of NEB expression may contribute to metastasis of tumor cells from the breast to the brain in humans with metastatic breast cancer.
El dibujo como método de estimulación cognitiva en adultos mayores sanos y pacientes con trastorno neurocognitivo: Implementación por medios virtuales como respuesta al aislamiento por pandemia de COVID-19
Authors: Sánchez-Gaviria Jesús , Forero Barbara , Espitia Angie , Montañés Patricia
Published: December 2020

Las restricciones por la pandemia de COVID-19 han impedido que los pacientes con demencia puedan asistir a espacios de acompañamiento e intervención neuropsicológica, por lo cual se hace necesario el uso de medios virtuales para la atención de esta población. Es por ello que en este artículo se presenta el desarrollo de un programa virtual de estimulación cognitiva por medio del dibujo de aves, en donde el propósito principal de la investigación fue describir y comparar el desempeño de pacientes colombianos con Trastorno neurocognitivo y adultos mayores sanos en un programa virtual de dibujo de aves. Ambos grupos tuvieron un desempeño diferente en los dibujos realizados antes, durante y después del programa, siendo posible inferir los procesos cognitivos o habilidades implicadas en su elaboración, así como las dificultades exhibidas según su diagnóstico o si atravesaban por un proceso de envejecimiento cognitivo normal
Prenatal maternal infections and psychopathology in childhood and adolescence: Findings from the ALSPAC birth cohort
Authors: Hall Hildigunnur Anna , Speyer Lydia Gabriela , Lombardo MIchael , Murray Aja Louise , Auyeung Bonnie
Published: December 2020

Aims: Studies have suggested that exposure to prenatal infections may be a risk factor in the aetiology of neurodevelopmental disorders such as schizophrenia and autism, but that its effects may differ by timing of exposure. Evidence on other psychiatric outcomes, however, is scarce and mixed. The aims of this study were to examine whether exposure to infections, at any point in gestation and during each trimester, is associated with increased odds of psychiatric disorders (pervasive developmental disorders, attention-deficit hyperactivity disorder, behavioural disorders and emotional disorders) at ages 7 and 14. Methods: Participants were n = 8859 mother and child pairs from the UK Avon Longitudinal Study of Parents and Children (ALSPAC) cohort. Exposure to prenatal infections was assessed for each trimester using maternal self-reports. Children’s psychiatric status was assessed using the parent-reported Development and Well-being Assessment (DAWBA). Logistic regressions were used to examine links between prenatal infections and child outcomes. Results: Half of the mothers reported an infection at some point during pregnancy and 7% of children were reported to have a psychiatric condition. Increased odds of children having any psychiatric disorder at age 14 were found in association with infections at any point during pregnancy, OR = 1.27 (95% CI 1.04, 1.55) and in the third trimester specifically, OR = 1.28 (95% CI 1.02, 1.61), after adjusting for the effects of potential confounds and other covariates. No other links were found in adjusted models. Conclusions: Findings suggest that associations between prenatal infections and children’s psychiatric disorders are weak to non-existent, after adjusting for the effects of other factors.
Using tertiary sulci to map the “cognitive globe” of prefrontal cortex
Authors: Miller Jacob , D'Esposito Mark , weiner kevin
Published: December 2020

Stuss (1984) considered the human prefrontal cortex (PFC) as a “cognitive globe” on which functions of the frontal lobe could be mapped. Here, we discuss classic and recent findings regarding the evolution, development, function, and cognitive role of shallow indentations, or tertiary sulci, in PFC with the goal of using tertiary sulci to map the “cognitive globe” of PFC. First, we discuss lateral PFC (LPFC) tertiary sulci in classical anatomy and modern neuroimaging, as well as their development, with a focus on those within the middle frontal gyrus (MFG). Second, we discuss tertiary sulci in comparative neuroanatomy, focusing on primates. Third, we summarize recent findings showing the utility of tertiary sulci for understanding structural-functional relationships with functional network insights in ventromedial and LPFC. Fourth, we revisit and update unresolved theoretical perspectives considered by Vogt and Vogt (1919) and Sanides (1964) that tertiary sulci serve as landmarks for cortical gradients. Together, the consideration of these classic and recent findings indicate that tertiary sulci are situated in a unique position within the complexity of the “cognitive globe” of PFC: they are the smallest and shallowest of sulci in PFC, yet can offer insights that bridge spatial scales (microns to networks), modalities (functional connectivity to behavior), and species. As such, the map of tertiary sulci within each individual participant serves as a coordinate system specific to that individual on which functions may be further mapped. We conclude with new theoretical and methodological questions that if answered in future research, will likely lead to mechanistic insight regarding the structure and function of human LPFC.
Consciousness, Religion, and Gurus: Pitfalls of Psychedelic Medicine
Authors: Johnson Matthew
Published: December 2020

This viewpoint identifies pitfalls in the study of psychedelic compounds including those that pose challenges for the potential use of psychedelics as medicines. They are: 1) Sloppiness regarding use of the term “consciousness;” 2) Inappropriate introduction of religious/spiritual beliefs of investigators or clinicians; and 3) Clinical boundaries and other ethical challenges associated with psychedelic treatments.
Constructive Friction Creates A Third Space for Art/Science Collaborations
Authors: Ellison Aaron M , Borden David Buckley
Published: December 2020

Successful interdisciplinary collaboration between artists and scientists is not about discovering “common ground,” but about deliberately creating a new space for collaboration. This novel space includes physical, virtual, and intellectual elements brought together through creation of a shared language and using it in open dialogue. Communication not only shapes the collaboration and leads to the creation of joint work, but also engenders new ways of working together and new levels of understanding. The co-authors interrogate a series of their art/science collaborations to identify essential, general principles for synergistic communication and productive collaborations between artists and scientists. [This paper has been accepted for publication in Leonardo]
Comparative study of EpCAM expression in polyps and adenocarcinoma of the distal colon
Authors: Shyshkin M. A. , Khrystenko T. O.
Published: December 2020

Annotation. ЕpCAM is known as a universal stem cell marker, however, the question of its value in colorectal cancerogenesis is still open. The aim of the research was to compare EpCAM immunohistochemical expression levels in polyps and adenocarcinoma of the distal colon. Pathohistological and immunohistochemical studies of biopsies of polyps and non-changed mucosa of 40 patients, as well as surgical material of 30 patients that underwent surgical treatment of colorectal cancer were carried out. The data were statistically processed using the STATISTICA® for Windows 13.0 package (StatSoft Inc., license № JPZ804I382130ARCN10-J). The median (Me), the lower and upper quartiles (Q1; Q3) were calculated, the comparison between the two groups of observations was performed using the Mann-Whitney test. It was figured out that the polyps are characterized by membranous pattern of EpCAM expression by epitheliocytes with the median equal to 65.22 (33.65; 78.94) CUOD. Comparative analysis of EpCAM expression levels in the polyps and histologically non-changed mucosa, as well as in two studied subgroups of the polyps revealed no significant differences. Colorectal adenocarcinoma is characterized by membranous-cytoplasmic pattern of EpCAM expression by cancer cells with the median equal to 90.86 (80.24; 99.02) CUOD. Comparative analysis of EpCAM expression levels in studied subgroups of the carcinoma (subgroups that correspond to the pTNM stages) revealed the tendency to increasing of EpCAM expression by cancer cells with statistically significant growth of the expression level median during the progression of the tumor from II to IV stages. Furthermore, it was established that the median of EpCAM expression is 28 % higher than the median of the marker expression in the polyps that is statistically significant: 90.86 (80.24; 99.02) CUOD vs. 65.22 (33.65; 78.94) CUOD, р˂0.05. Based on the data obtained, the difference in the patterns of EpCAM expression in the polyps and colorectal carcinoma is due to structural changes that happens to the molecule during colorectal carcinogenesis, moreover, significant increasing of EpCAM expression level at advanced stages of colorectal carcinoma reflects the acquisition of stemness by cancer cells.
Clinical and functional characteristics of the cardiovascular system in patients with paroxysmal atrial fibrillation
Authors: Seredyuk L. V. , Vakalyuk I. P.
Published: December 2020

Annotation. Atrial fibrillation (AF) is a potentially dangerous heart rhythm disorder that is diagnosed in 2 % of the population. Patients with AF have a five times higher risk of thromboembolic events. The reason for its appearance is stable coronary heart disease, hypertension, cardiomyopathy, hyperthyroidism. However, a review of recent studies suggests that psychological stress may also be a risk factor for AF paroxysm. The aim of the study was to investigate the clinical, psychological and functional characteristics of the cardiovascular system in patients with paroxysmal AF, considering the anxiety and depressive symptoms. The psychometric method combines the use of materials such as: psychosocial scale L. Reeder’s stress and perceived stress-10; hospital scale of anxiety and depression (HADS) to study the presence and level of affective disorders; PHQ-15 health questionnaire to assess somatization disorders; PHQ-9 health questionnaire to detect mental disorders of the non-psychotic register. The statistical processing of the obtained results was subjected to mathematical and statistical analysis using the computer program STATISTIKA-19 and the package of statistical functions of the program “Microsoft Office Excel”, classical methods of variation statistics. The results of the study show that the appointment of mebicar eliminates the manifestations of astheno-vegetative syndrome. Significantly reduces stress, anxiety and depressive symptoms, improves myocardial conduction and increases its contractility, normalizes lipid profile and electrolyte balance. Thus, the addition of mebicar to the standard of care helped to reduce stress and somatization disorders, reduces the score of anxiety and depression, increases the ejection fraction of the left ventricle and potentiates the manifestations of dyslipidemia. The prospect of clinical research is the feasibility of further implementation of the results in clinical practice.
Diagnostic significance of clinical and para-clinical signs of community-acquired pneumonia in children
Authors: Pasik V.Yu.
Published: December 2020

Annotation. Respiratory diseases are relevant in pediatric practice, which is associated with its widespread and frequent complications, especially in young children. The aim of the study was to assess the diagnostic value of clinical symptoms, laboratory and ultra-sonographic parameters in pneumonia in children of the first 3 years of life. A retrospective study of medical records of 218 children who were hospitalized in the department for young children diagnosed with pneumonia for the period from 2016 to 2018. The average age of children was 11.67±9.97 months and it was within the range from 1 month to 3 years. The ration of boys and girls was practically identical (51.8% and 48.2% accordingly). The first group included children aged under one year (the average age is 4.57±0.84 months; n=88). The second group included children aged from 1 to 3 years (the average age is 18.2±4.25 months; n=130). To characterize the information content of clinical and laboratory symptoms the study has used objective parameters defined as the operational characteristics of tests. The most important operational characteristics of diagnostic methods included: sensitivity (Se, sensitivity) and specificity (Sp, specificity). To check the statistical hypothesis on differences of absolute and relative frequencies, fractions, and ratios in two independent samples, the criteria of хі-square (χ2) was used. While detailing an anamnesis, the disease was more often related to untimely treatment and outpatient care. Various data were obtained on the absolute and relative risk, as well as the sensitivity and specificity of the localization of pneumonia depending on age. Therefore, the incidence of bilateral pneumonia was considered an indicator of risk. On admission to hospital, the body temperature of patients was 38.2±0.66°С. Most of the complaints were on the unproductive or productive cough. Besides, in some cases, shortness of breath and runny nose were mentioned. Thus, in young children with pneumonia, a diagnostically significant clinical symptom is a bilateral lung impression (82.6%), compared with right-handed (15.1%) and left-handed (2.3%), which is significantly more common in children under 1-th year of life compared with patients 1–3 years; laboratory features are probably higher levels of liver-specific enzymes – ALT and AST in children under 1 year; ultrasonographic indicators associated with the presence of pneumonia in young children include increased liver size, gallbladder deformity, the presence of sediment in the gallbladder, dyskinesia of the biliary tract, thickening of the gallbladder wall; children under 1 year of age have a risk of liver enlargement and biliary dyskinesia.
Spontaneous splenic rupture
Authors: Kozak I. O. , Sukhodolia S. A. , Kozak L. I. , Ladyshkin V. V.
Published: December 2020

Annotation. We represent a clinical case of spontaneous rupture of the spleen in a patient 35 years old without of signs of injury and pathological changes of the organ. Based on own clinical experience and literature review, the extreme rarity of such pathology, the atypicality of its clinical manifestations, the causes of diagnostic errors and grave consequences are considered. It is noted that in the operation for acute appendicitis in the absence of destructive changes in the appendix, it is mandatory to search for the cause of abdominal pain, one of which may be a spontaneous rupture of the spleen.
The technique of simultaneous laparoscopic operations in the treatment of gallstone disease and hiatal hernia
Authors: Halei M. , Dzubanovskij I. , Marchuk I.
Published: December 2020

Annotation. Aim of work – to evaluate the quality of medical aid for the regular and simultaneous treatment of patients with gallstone disease in combination with a hiatal hernia. To evaluate the safety of simultaneous operations in the treatment of such patients. Determine advantages and disadvantages of both treatment strategies. Assess the ergonomics of laparoscopic surgery techniques. For sampling the database, statistic collected at the laparoscopic surgery unit of the Volynian Regional Clinical Hospital was used. The number of patients was 332. Patients were formed into two groups: the group of simultaneous laparoscopic treatment (laparoscopic cruroraphy with Toupet fundoplication and laparoscopic cholecystectomy with advanced surgery technique) – the first group of 126 people, and the group with only one operation (laparoscopic cruroraphy) was performed – the second group of 206 patients. The method that was chosen in first group (simultaneous laparoscopic treatment with advanced technique) allowed to prevent re-hospitalization, one more operation, and all associated risks (surgical, anesthesiologycal). Though the cost was a slight increased time of surgery (52 minutes versus 41), as well as a slightly increased the average hospital stay (3.25 days versus 3.1 days) comparing to a single surgery group. Complication rate didn`t increased significantly (5.5% in the first group versus 6.3% in the second group), with zero mortality in both groups. These data allow us to notice the safety and value of this treatment method and to continue its research and testing. The method can be linked to increasing the efficiency of medical care by reducing the number of hospitalizations, the total hospital stay, and reducing the overall cost of treatment, minimizing the cost of dealing with the complications.
Evaluation of the relevance of the application of innovative teaching methods in the context of distance education
Authors: Gumeniuk N. I. , Romanovska O. O. , Matviychuk M. V. , Korolyova N. D. , Chorna V. V. , Khlestova S. S. , Humeniuk-Chaus J. K. , Polyarush V. V. , Sidorchuk T. M. , Angelska V. Y.
Published: December 2020

Annotation. The purpose of the work is to substantiate the feasibility of implementing innovative technologies, forms, and methods of teaching in the educational process of higher education institutions, as the main factor in the formation of professional skills of future professionals in terms of combined distance learning. The following methods have been using at work: biblio-semantic, historical, and content analysis. The issues of implementation of innovative teaching methods in higher education students in the conditions of distance learning are covered, namely: the creation of "intelligence map" on a given topic and independent work of students in "small group," the efficiency of application of "case technologies" in practical classes and conducting seminars in the format of a problem lecture. The importance of innovative training in the process of forming professional skills of future specialists in the conditions of combined classroom and distance education has been emphasizing.
Principle “student voices” as a tool of partnership cooperation at the department of pharmacology
Authors: Alchuk A. I. , Pashinska O. S. , Denisyuk O. M. , Voloshchuk N. I. , Marynych L. I.
Published: December 2020

Annotation. The article is devoted to the implementation of the principles of “student voices” and teacher`s feedback in the process of improving the teaching and learning pharmacology. There were introduced results of the students questionnaire, which were conducted in 2017, 2018, 2019, according to the questionnaire developed by us, together with teachers of the Department of Medical Psychology. Every year from 300 to 500 respondents were interviewed, and in 2019 another 247 4th year students were included in the survey. According to the results of the survey, 76–85% of respondents (3rd and 4th year students, respectively) did not change their attitude to the chosen specialty. 78% of respondents believe that the quality of education at the university is high. At the same time, about 90% of respondents are satisfied with the quality of lecture material, and about 88% of respondents are satisfied with the quality of practical classes. According to the assessment of studying at the department on a scale from “not at all interesting” to “very interesting”, 84.9% of respondents chose the answer “very interesting”. Assessment of the teacher's attitude to the student as a person showed a good attitude in 96% and unsatisfactory – in 3.9% of respondents. Students noted that to improve their knowledge and deeper understanding of the subject, they need to increase the number of practical classes (32% – 3rd year and 48% – 4th year). So, the data obtained made it possible to analyze the effectiveness of existing methods of teaching pharmacology, student satisfaction with the educational process, the final results and the quality of competencies. Also, to determine the role and function of the teacher in modern reality, to choose the vector of potential changes in the competencies of the teaching staff of the Department of Pharmacology.
Issues of stigmatization to mental patients from medical students and medical staff of psychiatric institutions and measures for its minimization
Authors: Chorna V.V. , Makhnyuk V.M. , Khliestova S.S. , Gumeniuk N.I. , Khliestova I.V.
Published: December 2020

Annotation. The aim of the study was to identify the presence of stigmatization among students of medical educational institutions and medical stuff of psychiatric institutions toward mental patients, to establish the causes and develop measures to minimize it. Methods were used in the work: bibliosemantic, historical, content analysis, as well as a questionnaire method using a specially designed questionnaire. Using Telegram, Microsoft Excel 2003 software, 1062 students were interviewed anonymously of 4–5 courses of medical institutions of higher education of Ukraine. The average age of students ranged from 20 to 22 years – 913 (85.9 %); from 23 to 24 years old – 119 (11.3 %) and from 25 to 26 years old – 30 (2.8 %). It was found that 93.8% of respondents from the total number of students surveyed are convinced that people with mental illness need special treatment; 87.9 % – were convinced that people who have mental illness pose a threat to society; 17.3 % respondents witnessed the humiliation of mental patients by working medical personnel in the presence of medical students. It is a fact, but in 2.1 % of cases, future doctors allowed themselves to offend patients who were hospitalized in psychiatric healthcare facilities during training. Thus, the inheritance of the Soviet system of medical education in the field of training young specialists for the mental health sector in Ukraine, which, unfortunately, has not experienced significant structural changes, is reflected in the behavior of the working medical personnel of psychiatric hospitals and the views of future doctors. Stigmatization of mental patients was carried out by every fourth medical worker (24.5 %) in psychiatric institutions in Odessa and every fifth medical worker in psychiatric institutions in Poltava (21.4 %) and Chernivtsi (20.9 %), which is violation of the moral and ethical principles of the doctor's behavior and unacceptable. The stigmatization of the mentally ill by medical students of medical schools is 2.1 %, which indicates that students use the negative example of the medical personnel of psychiatric institutions for their future medical activities.
Computational fluid dynamic analysis of blood flow through critical stenosis of the right coronary artery in human
Authors: J.Muhseen Saba , M. Hannun Rafid
Published: December 2020

The aim of this paper is to predict the hemodynamics properties of blood flow during in the Critical stenosis RCA . This paper examines pulsed , laminar blood flow through  state of the right coronary artery in patient  heart. Data for these case were taken from a catheter laboratory in the Thi Qar Heart Center . The case  for a man born in 1957 who has one stenosis in RCA with a stenosis of 80%. A non-Newtonian blood model characterized by the Carreau equation was used, and a 3D model was used with the governing equations analyzed using the specified volumetric method. The SIMPLE algorithm has been adopted to link pressure and speed during runoff. Geometric figures are drawn using Auto CAD software and combined with FLUENT. The results showed that the speed increased significantly in the area of stenosis. Non-Newtonian viscosity increases its effect near the center of stenosis. The total pressure is equal to diastolic pressure with little increase
Ks. Wojciech Kania
Authors: Longosz Stanisław
Published: December 2020

oficjalne
Rola Eucharystii w walce z szatanem u Ojców Kościoła
Authors: Borkowska Małgorzata
Published: December 2020

Although the Desert Fathers did not speak often about Eucharist, there are passages in their conferences showing that they had a great cult of the holy Mysteries and set a great value upon acquiring orthodox notions of it.
Nieśmiertelna książka Orygenesa
Authors: Ćwik Zbigniew
Published: December 2020

Ab amicis suis Ambrosio et Tatiana rogatus Origenes anno 234 in Caesarea Palaestinensi opus "De oratione" scripsit.
Najstarszy tekst "Vita S. Pauli Primi Eremitae" św. Hieronima
Authors: Degórski Bazyli
Published: December 2020

Delle tre biografie scritte da San Girolamo, la Vita S. Pauli e generalmente considerata la piu antica.
Termin "Eucharistia" w pismach Klemensa Aleksandryjskiego
Authors: Drączkowski Franciszek
Published: December 2020

Der Begriff "Eucharistie" tritt 21 mal in den Schriften des Clemens von Alexandria auf.
Zalążki ogólnokościelnej dyscypliny duchowieństwa w świetle postanowień I soboru nicejskiego (325)
Authors: Dudziak Jan
Published: December 2020

Der Verfasser beschreibt in dem Artikel die Hauptsatze der Berufspflichten der Geistlichkeit nach den Beschlussen des okumenischen Konzils zu Nizaa im Jahre 325.
Ikonografia Ducha św. w okresie patrystycznym
Authors: Filarska Barbara
Published: December 2020

The Author briefly discusses three types of images interpreted as probable representations of the Holy Spirit.
Problem wysłuchania modlitwy u Klemensa Aleksandryjskiego
Authors: Grzywaczewski Józef
Published: December 2020

Clemens Alexandrinus perfectum christianum gnosticum appellat. Gnosticus autem, qui homo mundo corde habetur, Deum et omnia in Deo amat.
Złoto i srebro jako pieniądz w łacińskiej literaturze patrystycznej okresu późnego cesarstwa rzymskiego
Authors: Jundziłł Juliusz
Published: December 2020

The article showed the situations, in which gold and silver are used as a money. The majority of information like these resulted from stylistic convention Fathers of the Church.
Ks. Jan Chrzciciel Alzog (1808-1878) historyk Kościoła i patrolog
Authors: Kiełbasa Antoni
Published: December 2020

Johann Baptist Alzog (1808-1878) war ein bekannter Kirchenhistoriker und Patrologie des XIX Jahrhunderts.
"Suavitas sermonis" św. Ambrożego na przykładzie diatryby "De Nabuthae historia"
Authors: Kozera Marek
Published: December 2020

Der heilige Augustinus, dessen 1600 Jahrestag der Taufe eben auf Ostern vorigen Jahres (1987) fiel, hat geschrieben, dass indem er Predigten des Bischofs von Mailand hl. Ambrosius horte.
Biblijna orientacja medytacji pachomiańskiej
Authors: Kurek Ryszard
Published: December 2020

La meditazione elaborata negli ambienti anacoretici assunse il significato di recitare a voce bassa, ed aveva come soggetto la parola di Dio.
O przyczynach zaniku diakonatu stałego w Kościele zachodnim
Authors: Marczewski Marek
Published: December 2020

Die ersten Jahrhunderte des Christentums waren eine Blutezeit in der Geschichte des standigen Diakonats.
Życie i działalność literacka Orozjusza
Authors: Obrycki Kazimierz
Published: December 2020

Hoc in commentariolo de vita ac litteraria activitate Orosii tractatur. Primum antiqui illi fontes exponuntur, in quibus certae et validae mentiones de Orosio factae sunt.
Egzegeza IV Ewangelii w pismach Ojców Apostolskich
Authors: Paciorek Antoni
Published: December 2020

Hoc in brevi articulo expositum est, quomodo locutiones ac ideae Joannis evangelistae in selectis scriptis (Epistola Clementis Romani ad Corinthios, Epistolae Ignatii Antiocheni, Epistola Barnabae) mutuatae sint.