bluuebunny/crossref_metadata_2025 huggingface dataset:
Efektifitas Pelatihan Konten Kreatif dan Pemasaran Digital UMKM di Kecamatan Gunung Kaler Kabupaten Tangerang
Authors: Komalasari Nia , Haryanto Haryanto , Djamaludin Djamaludin
Published: February 2025

. Media sekarang ada di dalam genggaman konsumen, untuk itu jika ingin meningkatkan omzet maka kita harus piawai membuat konten yang kreatif dan menarik dan menawarkannya di media sosial. Konten kreatif bisa membuat para pengguna media sosial (warganet) tertarik untuk selalu mengikuti informasi produk yang ditampilkan. Sementara para pelaku UMKM di Kecamatan Gunung Kaler Kabupaten Tangerang sebagian besar belum bisa membuat konten kreatif dan pemasaran di media sosial untuk menawarkan produknya. Tujuan penelitian ini adalah melihat sejauh mana peningkatan omzet UMKM setelah diberi pelatihan pembuatan konten kreatif dan penjualannya di media sosial. Metode yang digunakan pada penelitian ini adalah mix method, yaitu gabungan antara metode kualitatif dan metode dengan desain kuasi eksperimen dengan dua kelompok responden, yaitu kelompok sebelum diberi pelatihan dan setelah diberi pelatihan. Hasil  dari penelitian ini adalah nilai pengetahuan dan keterampilan sebelum diberikan pelatihan pembuatan konten Capcut dan pemasaran melalui media sosial dibandingkan dengan setelah diberi pelatihan jauh meningkat, demikian pula omzet harian yang diterima pasca pelatihan mengalami peningkatan setelah diuji menggunakan uji beda rata-rata paired t-tes. Kesimpulanya adalah dengan adanya pelatihan pembuatan konter kreator dan pemasaran menggunakan media sosial para pelaku UMKM mendapatkan pengetauan dan keterampilan yang baik sehingga bisa meningkatkan pendapatan harian secara signifikans.
Manajemen Komplain sebagai Upaya Meningkatkan Kepuasan Pasien di Rumah Sakit
Authors: Asriani Asriani , Putrawan Agus
Published: February 2025

Manajemen keluhan pasien merupakan aspek krusial dalam peningkatan kualitas pelayanan rumah sakit, di mana keluhan pasien tidak hanya dipandang sebagai bentuk ketidakpuasan, tetapi juga sebagai peluang berharga untuk perbaikan. Berbagai studi menunjukkan bahwa penerapan Total Quality Management (TQM) secara signifikan mengurangi jumlah keluhan pasien melalui perbaikan pada berbagai aspek seperti proses pendaftaran, kecepatan diagnosis, dan kemampuan komunikasi staf. Fasilitas pelaporan keluhan yang memadai, termasuk kotak saran, formulir, media sosial, dan call center, mempermudah pasien menyampaikan keluhan, yang kemudian ditangani dengan mekanisme yang responsif dan transparan. Sistem dokumentasi yang baik mencatat identitas pelapor, jenis keluhan, dan tindak lanjut, memungkinkan rumah sakit untuk mengelola dan menyelesaikan keluhan secara efektif dalam waktu 1x24 jam hingga 7x24 jam. Selain itu, evaluasi berkala dan tindak lanjut terhadap keluhan menjadi penting untuk mencegah terulangnya masalah yang sama. Penelitian juga menyoroti perlunya komitmen manajemen, sumber daya manusia yang terlatih, dan anggaran yang memadai, serta integrasi sistem informasi yang mendukung proses penanganan keluhan secara real-time. Dengan demikian, penanganan keluhan yang efektif berkontribusi pada peningkatan kepuasan pasien, loyalitas, dan citra positif rumah sakit.
ASSESSMENT OF DRUG UTILISATION PATTERN FOR STROKE PATIENTS IN TERTIARY CARE HOSPITAL
Authors: Saha Sankha Shubra , Patel Nivedita , Patel Vidit , Lokhanwala Zainab , Patel Harsh P , Panchal Parthkumar Janakbhai , Vaghela Prashant , Kakadiya Jagdish , Chakraborthy Gunosindhu
Published: February 2025

BACKGROUND: Stroke represents a major public health concern globally, with significant implications for both patients and healthcare systems. The appropriate use of medications is essential in managing strokes to lower the risk of serious disease and demise. Pharmacotherapy plays a central role in the acute and long-term management of stroke, encompassing a range of medications aimed at preventing recurrence, managing risk factors, and promoting recovery. OBJECTIVE: Evaluating the pattern of drug usage in stroke patients admitted to a specialized referral hospital. MATERIALS AND METHODS: In this study data of the patients receiving treatment of stroke is obtained. Total 154 patients’ data was collected and observed from Parul sevashram hospital. In the data collection analysis form, the data was reported and analysed using graphical representations and is summarized. RESULT: In 154 patients the common medications like enoxaparin, heparin, aspirin, clopidogrel were used. Various classes of antihypertensive drugs were prescribed for 53 hypertensive patients, while phenytoin was administered to those with seizures. Atorvastatin and mannitol were also frequently prescribed. Antibiotics, lactulose, and cerebral activators like citicholine were utilized to address specific needs. CONCLUSION: The study concluded that males are more prone to stroke and patients with age of 46-60 years have more common occurrence for stroke with risk factor of hypertension and high cholesterol levels. Atorvastatin, aspirin and clopidogrel is the usually prescribed drug in the study. To promote safe and efficient drug use, the selection of drugs should be focused.
Anestesia em pacientes de alto risco na cirurgia geral: Protocolos de segurança e manejo perioperatório
Authors: Choptian Junior Mário Ciro , Silveira Natyele Rippel , Muniz Karen Duran , Silva Brenda , Müller Murad Livia Maria , Silva Gabriela Vieira , Rosa Fonseca Gustavo Santa , Santos Costa Luís Henrique , De Paula Douglas Marques , Santos Caldeira Manoel Victor , Dameda Luiz Eduardo , De Almeida Barbosa Maria Clara Marques , Castro Felipe Rodrigues
Published: February 2025

A anestesia em pacientes de alto risco submetidos à cirurgia geral representa um desafio significativo para a equipe multidisciplinar, exigindo protocolos rigorosos de segurança e manejo perioperatório. Este estudo teve como objetivo revisar as principais estratégias anestésicas utilizadas nessa população, abordando desde a avaliação pré-operatória até o monitoramento pós-operatório. A metodologia baseou-se em uma revisão integrativa da literatura, analisando estudos recentes sobre técnicas anestésicas, monitorização intraoperatória e medidas preventivas para minimizar complicações. Os resultados indicaram que a avaliação pré-operatória detalhada, a escolha criteriosa da técnica anestésica e a monitorização avançada são fatores determinantes para reduzir a morbimortalidade em pacientes com comorbidades. Além disso, a atuação da equipe multidisciplinar e a adoção de protocolos estruturados foram associadas a melhores desfechos clínicos. Conclui-se que o manejo anestésico de pacientes de alto risco deve ser personalizado, equilibrando a aplicação de diretrizes baseadas em evidências e a necessidade de adaptação conforme o perfil individual do paciente.
Resilience and Adaptation: Plant Responses to Environmental Stressors
Authors:   Department of Life Sciences, Khwaja Fareed University of Engineering and Information Technology, Rahim Yar Khan, Pakistan, Sameen Saira
Published: February 2025

Understanding plant resilience and how plants cope with environmental challenges such as climate change and air pollutants is an important focus in biology. The current study creates a potential complexity of regulatory pathways under abiotic stresses, including drought, salinity, flooding (hypoxia), heat stress, and heavy metal toxicity in plants. To allow plants to survive under these stresses, integrated physiological, biochemical, and molecular strategies were permuted by controlling water transport systems together with the production of antioxidants and genetic adaptation. For example, plants may close stomata to reduce water vapor during droughts and stimulate root development for improved water absorption. For instance, it leads to metabolic changes necessary for living in an oxygen-deprived environment like flooding. In addition, some recently developed biotechnology approaches as strategies for the amelioration of plant tolerance via genetic modification and rhizosphere microorganism supplementation are also examined. Due to the complex interplay of stress responses and adaptation mechanisms, understanding these relationships is crucial for designing sustainable agriculture practices. A new understanding of mechanisms dealing with plants’ resistance towards biotic and abiotic stresses can be built by these kinds of interdisciplinary approaches which lightens the need for more research so that plant productivity can be improved under stressed environmental circumstances. Eventually, food preservation and overall ecosystem balance can be achieved by implementing the research results in common agricultural and farming practices.
Integrating Biotechnology into Plant Biology: Challenges and Future Directions
Authors:   Department of Life Sciences, Khwaja Fareed University of Engineering and Information Technology, Rahim Yar Khan, Pakistan, Sameen Saira , Khalil Bilal
Published: February 2025

Integrating biotechnology into plant biology has emerged as a critical method to cope with the escalating global demand for plant-based reservoirs amidst a growing populace and environmentally demanding situations. This review paper explores the current conditions, demanding situations, and instructions for biotechnological programs in plant science. We have analyzed the key areas of advancement, which consist of transgenic plant development, gene editing strategies, bioinformatics in plant research, metabolic engineering, epigenetics in crop improvement, synthetic biology for novel plant structures, and microbiome studies. The paper highlights how technology like CRISPR/Cas9 has revolutionized crop improvement, permitting precise genetic changes for better yield, stress tolerance, and dietary content. To research complicated plant genetic data and enable powerful breeding strategies, we cope with the convergence of bioinformatics and machine learning strategies. The paper additionally discusses the significance of epigenetics in comprehending heritable capabilities and the opportunities of metabolic engineering in the biofuel era. We additionally study the new field of plant synthetic biology and how it might be used to develop engineered microbiomes and sensor effector systems. The paper concludes by analyzing the complications in public recognition, regulatory frameworks, and the need for interdisciplinary procedures to recognize the ability of plant biotechnology to address international food protection and sustainability issues.
Aplicación del Modelo Hidrodinámico TELEMAC-2D en un Tramo del Río Paraná
Authors: Pairetti Lucía C. , Casanova Luciano V. , Peruzzo Florencia C. , Riccardi Gerardo A. , Basile Pedro A.
Published: February 2025

Se presenta la aplicación del modelo matemático hidrodinámico bidimensional horizontal TELEMAC-2D en un tramo del río Paraná entre los km 452 (Puerto San Martín-PSM) y km 405 (Alvear- ALV). La modelación fue realizada en régimen de flujo permanente, determinándose profundidades y niveles de agua, velocidades en dos direcciones integradas en la vertical y caudales. La calibración del modelo consistió en el ajuste del coeficiente de rugosidad de Manning que aseguraba la mejor aproximación entre niveles hidrométricos observados y simulados en el km 416 (Rosario-ROS) y en km 452 (PSM) en los distintos escenarios. Los resultados fueron empleados en trabajos posteriores, como base hidrodinámica para la simulación de dispersión de contaminantes, ante diferentes alternativas de volcamiento de efluentes cloacales.
British Colonial Strategy in Malaya in the 19th Century: Deliberate Global Strategy or Geopolitical Necessity?
Authors: WEN Yutong , Liu Chenglin
Published: February 2025

The Industrial Revolution drove Britain’s globally strategy in the 19th centu-ry, which saw the Malay Peninsula’s geographic location and resources as key. The process of British colonization in Malaysia was as much the result of deliberate strategic planning as it was of geopolitical in rivalry and flexibil-ity. Britain progressively increased its authority over the Malacca Straits by managing tin and rubber assets. And it would strengthen her hold over the area. Britain first focused mostly on the security of shipping in the Indian Ocean. It did not see the strategic value of the Malay Peninsula until rivalry with other powers increased. Adopting “informal imperialism” and “sub-im-perialism,” Britain indirectly controlled the Malay area by means of trade control and co-operation with local the rich and famous. And its lower the cost of conflict but also causing social divisions and laying the seeds of later ethnic conflicts and independence movements. British colonial advances on the Malay Peninsula mixed global strategies and geopolitical reality is un-spoken threats due to the variety and complexity of imperialism.
Prevalence and Antibiotic Resistance Patterns of Staphylococcus Aureus in Dermatological Infections: A 5-Year Retrospective Study
Authors: Asma Khan  , Nasir Ali  , Sameen Fatima  , Ayesha Jamshaid  , Akif Saeed  , Muhammad Ali Zahid
Published: February 2025

Background: Staphylococcus aureus (S. aureus) is a leading cause of dermatological infections, with rising methicillin-resistant S. aureus (MRSA) cases posing significant therapeutic challenges. The increasing antibiotic resistance necessitates continuous surveillance to inform treatment strategies. However, limited longitudinal data exist on resistance trends in dermatological infections, especially in tertiary care settings. Objective: This study aimed to assess the prevalence and antibiotic resistance patterns of S. aureus in dermatological infections over a five-year period, identifying risk factors associated with MRSA infections. Methods: A retrospective observational study was conducted from January 2020 to December 2024 in multiple tertiary care hospitals. A total of 850 clinical samples were analyzed. Inclusion criteria included patients diagnosed with dermatological infections, while those with systemic infections were excluded. S. aureus isolates were identified using microbiological and molecular techniques, with antimicrobial susceptibility testing performed per CLSI guidelines. Ethical approval was obtained (IRB No: 2024-0123). Statistical analysis was performed using SPSS v28.0, applying chi-square, t-tests, and logistic regression. Results: MRSA prevalence was 38.9% (331/850), with the highest resistance observed against penicillin (95.3%) and erythromycin (56.7%). Vancomycin and linezolid showed the lowest resistance (5.8% and 4.1%, respectively). Older age (OR: 2.17, p<0.001), prior antibiotic use (OR: 3.84, p<0.001), and hospital-acquired infections (OR: 4.12, p<0.001) were significantly associated with MRSA infections. Conclusion: The increasing MRSA prevalence highlights the urgent need for targeted antimicrobial stewardship and infection control measures. Strengthened surveillance programs and judicious antibiotic use are crucial to mitigating resistance trends. Keywords: Staphylococcus aureus, MRSA, antibiotic resistance, dermatological infections, antimicrobial susceptibility, tertiary care hospitals.
Enhancing Sedation Management in Mechanically Ventilated Patients in the Critical Care Unit
Authors: Abdul Samad  , Summiya Rahman  , Syed Ali Kazmi  , Muhammad Yasir  , Haider Ali Shah  , Zubair Sharif
Published: February 2025

Background: Sedation management in mechanically ventilated patients in the ICU is critical for optimizing patient outcomes. This study aimed to evaluate sedation practices and their impact on clinical outcomes in critically ill patients. Methods: A prospective observational research was performed including 196 ICU patients on mechanical ventilation. Demographic information, primary diagnoses, sedation procedures, duration of mechanical breathing, length of stay in the ICU and hospital, and clinical outcomes were documented. sedation was administered in accordance with a standardized protocol including sedatives like propofol, midazolam, and dexmedetomidine. Multivariate regression analysis was conducted to ascertain predictors of ventilation duration. Results: The average age of patients was 62.5 years, with respiratory failure as the predominant diagnosis (43.4%). The mean duration of mechanical ventilation was 7.8 days, accompanied by an intensive care unit stay of 12.5 days and an overall hospital stay of 18.4 days. Mortality was 14.3%, and 20.4% of patients acquired ventilator-associated pneumonia (VAP). Propofol was the predominant sedative utilized (48.5%), succeeded by midazolam (35.7%) and dexmedetomidine (15.8%). Patients administered propofol exhibited the briefest breathing duration, whereas those treated with midazolam demonstrated the most prolonged length. Multivariate regression indicated that age, APACHE II score, adherence to sedation protocols, and dexmedetomidine usage were significant predictors of breathing duration. Delirium and ventilator-associated pneumonia (VAP) were correlated with extended mechanical ventilation. Conclusion: Enhancing sedation techniques, such as compliance with sedation guidelines and judicious application of dexmedetomidine, may decrease the time of mechanical breathing and enhance patient outcomes. Delirium and ventilator-associated pneumonia (VAP) were recognized as significant determinants of extended mechanical ventilation. Additional research is required to enhance sedation protocols for critically ill patients.
Frequency and Risk Factors of Acute Appendicitis in Patients with Equivocal Appendicitis
Authors: Safwan
Published: February 2025

Objective: “To determine the frequency of acute appendicitis in patients with equivocal appendix; CT interpretation and to assess risk factors that favor acute appendicitis in patients with equivocal appendix. Study design and Setting: This Cross sectional study was conducted at General Surgery Department of Agha Khan University Hospital Karachi for 6 months October 2022 to March 2023. Patients and method: After meeting selection criteria 172 patients were enrolled. The patients’ data was filled using a performa, including details regarding age, gender, Neutrophil-to-lymphocyte ratio, and WBC count Using HIMS database by data collectors. The Alvarado score greater than 7 was followed with CT scan and Histopathology. All the collected data was entered and analyzed on SPSS version 20. Results: The mean age of the patients was 35.06±14.24 years, 89 (51.7%) patients were male and 83 (48.3%) were diabetics. Appendicitis was detected on CT in 80 (46.51%) patients. In patients with positive appendicitis on CT, the mean neutrophil count was 88.87±6.58, mean lymphocyte count was 14.8±3.07 and mean NLR was 6.27±1.22. In negative patients was 88.74±6.57 (p-value=0.260). In patients with positive appendicitis on CT the and in negative appendicitis on CT patients was 14.75±2.92. In negative patients mean neutrophil count was 6.22±1.17, mean lymphocyte count was 14861.07±3066.26 and mean NLR was 14751.52±2917.27. The difference in parameters was insignificant whether patients were positive or negative for acute appendicitis. Conclusion: This study concludes that the frequency of acute appendicitis in patients with equivocal appendicitis as determined by CT interpretation is 46.51% while factors include age, gender, BMI, diabetes, and raised NLR showed no association with appendicitis on CT scan.
Exploring Socio-Economic Factors and Business Profiles: A Holistic Study of Small-Scale Entrepreneurship Dynamics
Authors: Joshi Kamal ,   School of Management and Commerce Medhavi Skills University Sikkim India
Published: February 2025

This research paper delves into the multifaceted interplay between socio-economic variables and small-scale entrepreneurship, shedding light on the factors influencing entrepreneurial pursuits. Drawing from an extensive survey of 240 entrepreneurs, this study explores the impact of various socio-economic factors on the development and performance of small-scale businesses. The research reveals compelling insights into how age, gender, caste, religion, education, marital status, family background, prior experience, and financial aspects shape entrepreneurial decisions and outcomes. The study unveils intriguing patterns through meticulous data analysis, such as the influence of familial entrepreneurial history and the significance of education as an entrepreneurial catalyst. Moreover, the study underscores the urban advantage for fostering entrepreneurial endeavours due to increased access to amenities and opportunities. The findings highlight that the reasons for selecting specific business lines and the stages of business growth are intricately linked to socio-economic determinants. This paper presents an in-depth analysis of these variables’ effects on small-scale entrepreneurship. It suggests implications for policymakers, stakeholders, and prospective entrepreneurs aiming to navigate the complex entrepreneurial landscape.
Role of Media in Transforming Political Culture: A Comparative Study of ARY and Geo News in Political Agenda Setting
Authors: Akram Sidra , Fatima Mehwish , Anwar Rukhsar
Published: February 2025

Aim of the Study: This study analyses the two famous TV channels ARY and Geo News particularly, to investigate their political debate shows i.e. “Off the Record” & “Capital Talk”, which might be cornerstones in political agenda setting, predominant on the country's broadcasting channels. This study investigates at how media influences public opinions and encourages people to change their mindset. This study also highlights how these two talk shows can shape what people think is important and what they should be concerned about.  
Methodology: This research adopts a quantitative approach to how ARY News and Geo News affect political awareness among the people of Pakistan. Talk shows like “Capital Talk by Hamid Mir” and “Off the Record by Kashif Abbassi” are focused due to their high viewership. A total of (n=50) respondents were selected using a stratified random sampling technique. Participants were chosen based on age, gender, education level, and affiliations to ensure a diverse representation. The sample included people from urban and rural areas to reflect different regions of the country.
Findings: Media significantly influences public opinion and shapes political culture in Pakistan. ARY and Geo News, as leading news channels, have played a crucial role in establishing the political agenda and framing the public discourse. Both ARY and Geo News have demonstrated a considerable influence on establishing political agendas.
Conclusion: Media access acts like a “Magical Key”. It gives people a vast amount of information and helps them stay connected. The proposed study concludes that people can find a variety of viewpoints through news channels and online platforms. They can participate in discussions and create their own opinions. However, it's crucial to critically assess the information to gain a complete understanding of the relevant issues.
Shaping masculinity through control: Unveiling the impact of paternal authoritarian parenting on child gender role identity
Authors: Saif Ullah  , Khalil Ur Rehman
Published: February 2025

This study seeks to explore the influence of paternal parenting styles associated with masculinity on the development of gender role identity in children. Data was collected from male and female graduates as well as undergraduates at Hazara University Mansehra to address the research questions. Data was collected using a quantitative approach, employing the Bem Sex Role Inventory to evaluate masculinity among the study participants; along with the Paternal Authority Questionnaire, data collection was conducted using a structured questionnaire. A sample of 370 individuals was utilized to collect data at the selected university. The method of Systematic sampling was utilized to gather data from participants. The statistical data was analyzed through univariate, Bi-variate and multi-variate methods. A comprehensive analysis was performed to determine the relationship between dependent and independent variables. The chi-square and gamma association results between the Authoritarian Parenting Style and level of Masculinity were statistically significant and negatively associated.
Estrategias metodológicas para la enseñanza-aprendizaje en los estudiantes del sub nivel básica elemental de la unidad educativa Rvdo Jorge Sánchez Moreno
Authors: Gordillo Mera Sabina Marlene , Silverio Valle Erwin Leonardo , Espinoza Rojas Stalin Jeovanny , Moncayo Peña Ana Elizabeth , Padilla Rosario Thalía Gabriela
Published: February 2025

The research is about Methodological strategies for teaching-learning in students of the basic elementary sub-level of the educational unit Rvdo Jorge Sánchez Moreno. The general objective is to analyze the implementation of methodological strategies in the teaching-learning process in students, the specific objectives Theoretically identify the methodological strategies in the teaching-learning process in students of basic elementary of the Educational Unit Rvdo Jorge Sánchez Moreno, to improve the understanding of learning. Evaluate through the application of research instruments the effectiveness of methodological strategies in the teaching-learning process, to improve the understanding of learning. Propose methodological strategies for the teaching-learning process, how techniques for collecting information were used observation guides, field diaries and for the interview the interview guide instrument was used, it was applied to 1 teacher and 12 students of the sub-elementary level. The results obtained from the observation of the teacher revealed that she has an optimal academic training and the ability to solve various problems in the educational environment. However, a significant lack of integration of Information and Communication Technologies (TIC) in the applied methodological strategies was observed, which could enrich the teaching-learning process. It is concluded that it is crucial to implement continuous training programs for teachers in the use of digital tools and active methodologies that integrate TIC effectively, this will improve teaching-learning.
Analysis of the Impact of Illegal Parking on Consumer Purchase Interest: Case Study of Indomaret Jl. Srijaya Negara, Palembang
Authors: Eogenie Lakilaki  , Rusdianto  , Murlita  , Nova Tri Evriani  , Muhammad Zaky Ramadhan  , Reza Junita
Published: February 2025

The phenomenon of illegal parking in public areas, particularly around shopping centers like Indomaret on Jl. Srijaya Negara, Palembang, has become an urgent issue, disrupting traffic order and affecting consumer purchasing interest. This study explores the impact of illegal parking on consumer purchasing interest at Indomaret Jl. Srijaya Negara, Palembang. The method used in this research is qualitative with a case study design. The study population consists of consumers shopping at Indomaret, with informant selection using a purposive sampling technique. The instrument used is semi-structured interviews, and data analysis is conducted using the Miles & Huberman model. Interview results indicate that illegal parking creates discomfort and concerns about vehicle security, negatively impacting consumer purchasing decisions. In conclusion, illegal parking significantly impacts consumer purchasing interest, and Indomaret management needs to improve parking facilities and security to attract more customers.
Kerion Celsi and erythaema nodosum in childhood
Authors:   University of Szeged Albert Szent-Györgyi Medical Center Department of Dermatology and Allergology, Csoma Zsanett Renáta , Tajti Zsanett , Pósfai Éva , Hánis Csilla , Gyulai Rolland Péter
Published: February 2025

Kerion Celsi is a markedly inflammatory presentation
of tinea capitis, usually caused by Microsporum and
Trichophyton infections. Rapid introduction of aggressive systemic antifungal therapy is pivotal in the treatment. Erythema nodosum is a hypersensitivity reaction
characterized by red, tender, nodular lesions usually on
the pretibial surfaces; the most common etiologic causes in childhood are infections. Erythema nodosum is an
“id” or dermatophytid reaction in kerion Celsi; the hypersensitivity reaction is the consequence of vast amount
of fungal antigens. There are only a few case reports in
the literature on the common occurrence of kerion Celsi and erythema nodosum in children, the authors find
their case worthy of presentation because of this rare
constellation.
The role of dermatopathology in unusual and severe cutaneous infections
Authors:   University of Szeged Albert Szent-Györgyi Medical Center Department of Dermatology and Allergology, Varga Erika , Korom Irma , Németh István Balázs , Csoma Zsanett Renáta , Szolnoky Győző , Zoltán Zsófia , Nagy Boglárka , Honfi Vivien , Manczinger Máté , Tajti Zsanett , Kui Róbert , Terhes Gabriella , Juhász Hajnalka , Virok Dezső , Piukovics Klára , Adamkovich Nóra , Kárpáti Krisztina , Hajdú Edit , Pósfai Boglárka , Dósa Sándor , Kemény Lajos , Gyulai Rolland
Published: February 2025

The diagnosis of severe dermatological infections is usually
not the pathologist’s task, but sometimes the pathological
diagnosis enables the beginning of the targeted or even lifesaving therapy. An infectious disease is considered unusual
when it is rare in the given climate or the causative agent
normally not cause human illness, or when the disease itself
is very rare. In the case of an uncommon disease with generalized skin symptoms and possibility of infectious origin
skin biopsy is easily feasible, and the relatively quick and
precise „bed-side” histological diagnosis could be lifesaving. Authors present such rare infectious diseases diagnosed by dermatolpathologist.
The UHPLC-HRMS profiling, in vitro-antioxidant and pancreatic lipase inhibitory activities of Peronema canescens leaves extract and fractions from Indonesia
Authors: Suryani Ade Erma , Nisa Khoirun , Handayani Sri , Darsih Cici , Wuryastuty Hastari , Yanuartono Yanuartono
Published: February 2025

This study aims to identify metabolite compounds and determine the in vitro antioxidant and pancreatic lipase inhibitory activity of Peronema canescens Jack extracts and fractions. The results of phytochemical content showed that the ethyl acetate (FEA), n-butanol (FB), and aqueous (FA) fractions had significantly higher amounts of phenolic and flavonoid compounds than other fractions. It is linear with the antioxidant activity of FEA, FB, and FA, producing very strong to strong antioxidant activity. N-hexane fraction (FH) showed significant terpenoid content and a strong inhibitory effect on the lipase enzyme. Phytoconstituents in the extracts and fractions were profiled using ultra-high-performance liquid chromatography-high resolution mass spectrometry equipped with principal component analysis to classify chemical compounds. Diosmetin and pinoquercetin compounds were identified as being present abundantly in FEA. Meanwhile, terpenoid compounds and fatty acids are abundant in FH, including 7-oxodehydroabietic acid, oleanonic acid, oleanolic acid, docosanamide, eleostearic acid, ethyl linolenic acid, 1-stearoylglycerol, 9-oxo-10 (E), 12 (E)-octadecadienoic acid, and 12-oxo-phytodienoic acid. These findings indicate that FEA contains bioactive compounds that increase antioxidant activity, while FH contains many bioactive compounds with pancreatic lipase inhibitory effects. Further research is required to determine the correlation between the amount of active compound content and the bioactivity of P. canescens leaf extracts and fractions. In addition, further research using experimental animals and optimization of safer solvents will provide more comprehensive bioactivity information and increase our best knowledge of ethnomedicine based on P. canescens herbal preparations.
Quantum Transport in Topological Matters under Magnetic Fields
Authors: 强晓斌  , 卢海舟
Published: February 2025

Topological matters include topological insulator, topological semimetal and topological superconductor. The topological semimetals mainly concerned in this paper are three-dimensional topological states of matter. They are simply divided into Weyl, Dirac, and nodal-line semimetals according to the touch type of the conduction band and the valence band, and genalrally have topologically protected Fermi arcs at certain surfaces. We review our recent works on quantum transport in topological semimetals, according to the strength of the magnetic field. Near zero magnetic fields, there are competitions between the
positive magnetoresistivity induced by the weak anti-localization effect and negative magnetoresistivity related to the nontrivial Berry curvature. We propose a fitting formula for the magnetoconductivity of the
weak anti-localization. We expect that the weak localization may be induced by inter-valley effects and interaction effect, and occur in double-Weyl semimetals. We propose the conductivity correction
Main complaints identified by parents of children with developmental delays during the initial consultation: a 10-year all-case study
Authors: Kusumoto Yasuaki , Takahashi Eri , Takaki Kenji , Matsuda Tadamitsu , Nitta Osamu
Published: February 2025

Background

In Japan, the child development support initiative is one of the government’s daycare support programs for children with disabilities. Children, aged 0–6 years, who are not attending elementary school can participate in the initiative and receive various support. Reports on the approaches taken by private child development support centers and the guardians’ perceptions are increasing. Conversely, information from public child development support centers, which serve as places for initial developmental consultation, is extremely scarce. Moreover, there are no nationwide reports on the main complaints from each region, which are of concern to the parents. This study aimed to clarify children’s gender and age, presence of referral sources, and characteristics of the main complaints obtained during the initial consultation with parents of children with developmental delays, who used a public developmental support center in a medium-sized city in Tokyo.

Methods

This study included 1,241 parents of children with developmental delays (average 40.3 months, range 2–87 months). Five questions regarding each child’s characteristics (gender, age in months, and medical diagnosis), referral sources for the use of support centers, and main complaints that they would like to discuss at the initial consultation, were asked. The participants were asked to describe their main complaints (specific consultation details) as precisely as possible. From the free-form descriptions of the main complaints, 137 codes were extracted and grouped into 13 categories. Participants were divided into two groups according to the presence (n = 122) or absence (n = 1,119) of a medical diagnosis. The t-test, chi-square test, and Fisher’s exact probability test were used to examine differences between the two groups. Logistic regression analysis with forced entry was performed to examine whether the factors related to the main complaints raised by parents of children with developmental delays differed depending on the presence or absence of a medical diagnosis.

Results

The most common chief complaint at the time of the initial consultation was “language development” (43.9%), followed by “childcare and preschool counseling” (15.4%), “hyperactivity/inattention” (13.9%), and “general developmental issues” (13.6%). The regression analysis revealed that gender, age (months), and general developmental issues were factors associated with the presence or absence of a medical diagnosis were gender, age in months, and general developmental issues. The odds ratios (95% confidence intervals) were 1.573 (1.056–2.343) for gender, 0.988 (0.976–1.000) for age (months), and 0.421 (0.200–0.886) for general developmental issues.

Conclusion

Professionals involved in child development support are expected to have broad knowledge of various developmental issues as well as comprehensive knowledge of local childcare and schooling systems.
Translating Tamil God into Sanskrit in Vedāntadeśika’s Dramiḍopaniṣattātparyaratnāvalī
Authors: Akepiyapornchai Manasicha
Published: February 2025

This study explores the Śrīvaiṣṇavas’ commitment to upholding both the Sanskrit and Tamil scriptures or ubhayavedānta (literally, the dual Vedāntas). In particular, it focuses on how one of the most influential post-Rāmānuja ācāryas in the community, Vedāntadeśika (1269–1369), supported the two-scriptures principle in his Dramiḍopaniṣattātparyaratnāvalī. In this work Vedāntadeśika summarizes and translates the Tamil scripture, the Tiruvāymoḻi of Nammāḻvār, arguably the most authoritative South Indian Vaiṣṇava poet of a group collectively known as the Āḻvārs (ca. sixth to tenth century), into Sanskrit. I argue that Vedāntadeśika’s main goal is to secure the status of Nammāḻvār’s Tiruvāymoḻi as the Tamil Vedānta or Upaniṣad (and as the Tamil Veda in some cases). His attempt to bridge the gap between the Sanskrit and Tamil scriptures can be seen in three different aspects: their scriptural status, theology, and linguistic expression. Vedāntadeśika reinforces the scriptural status of the Tirūvāymoḻi, restructures the text so that it consistently illustrates God’s qualities, similar to the Sanskrit Upaniṣads, and, through the linguistic medium of Sanskrit, deemphasizes the poetic tropes of classical Tamil love poetry. While there were other summaries of the Tiruvāymoḻi before, during, and after his time, Vedāntadeśika’s summary is remarkable for its systematic approach and clear agenda.
New Sources of Han Verse
Authors: Waring Luke
Published: February 2025

Manuscripts excavated and looted from tombs in recent decades have greatly enriched our understanding of Western Han verse. Some of these documents have been designated by scholars as poems, and a few have even been assigned to particular poetic genres. In this article, however, I am less concerned with sorting texts into neat formal or generic categories and more interested in exploring the range of texts and contexts in which verse was employed. To that end, I introduce, analyze, and at least partially translate five new or little-known texts retrieved from various Western Han sites that make extensive use of rhyme and metrical rhythm: *Xiangma jing 相馬經 from Mawangdui M3, Tang Le 唐勒 from Yin- queshan M1, Wang Ji 妄稽 and Fan yin 反淫 from the looted Peking University manuscript corpus, and *Daowang fu 悼亡賦 from Haihunhou M1. Some of these documents are very similar to sources in the transmitted literature, while others are quite different from any verse previously known from the period. Taken together, however, they greatly enhance our understanding of the different ways verse functioned in various Western Han cultural contexts.
Hermeneutic Strategies of Mesopotamian Scholars
Authors: Baragli Beatrice , Kikuchi Saki
Published: February 2025

Commentaries represent the best-known evidence for scholarly activities and the exegetical tradition of Mesopotamia. However, commentaries were not the only textual expressions of exegetical activity and scholarship took many different forms. The aim of this article is to elucidate the ways and purposes of the use of various hermeneutic practices other than the writing of commentaries. By analyzing mostly hemerological compilations and simultaneous bilingual compositions, a particular kind of bilingual text, this article illustrates the multiplicity of forms, functions, and scholarly strategies of exegesis and how they are deployed for different kinds or genres of texts. These alternative strategies will be compared to commentaries and their unique features and limitations will be highlighted through an analytical approach.
Lexicon and Grammar in the Aramaic Land Description Ostraca from Idumea
Authors: Notarius Tania
Published: February 2025

This article is based on the corpus of Aramaic epigraphic cadastral documents published in Bezalel Porten and Ada Yardeni, Textbook of Aramaic Ostraca from Idumea, vol. 5 (University Park, PA: Eisenbrauns, 2023). The lexicon and syntax of these texts present a number of intriguing phenomena, and the examination of these phenomena allows the clarification of the reality behind the words. In particular, this article discusses ellipsis, omissions, and the syntax of captions as part of scribal conventions, as well as some technical terms and groups of lexemes that belong to the vocabulary of the land descriptions.
Review of Arab Traders in Their Own Words: Merchant Letters from the Eastern Mediterranean around 1800
Authors: Hathaway Jane
Published: February 2025

Arab Traders in Their Own Words: Merchant Letters from the Eastern Mediterranean around 1800. By Boris LieBrenz. Handbook of Oriental Studies I, vol. 165. Brill, 2022. Pp. ix + 701. $215.
Review of Writing Egypt: Al-Maqrizi and His Historical Project
Authors: Khalek Nancy
Published: February 2025

Writing Egypt: Al-Maqrizi and His Historical Project. By Nasser Rabbat. Edinburgh University Press, 2022. Pp. xi + 337. $125 (cloth); $29.95 (paper).
Review of The Women Who Ruled China: Buddhism, Multiculturalism, and Governance in the Sixth Century
Authors: Buckelew Kevin
Published: February 2025

The Women Who Ruled China: Buddhism, Multiculturalism, and Governance in the Sixth Century. By Stephanie Balkwill. University of California Press. Pp. xx + 262. $34.95 (paper); open access.
Review of Strange Tales from Edo: Rewriting Chinese Fiction in Early Modern Japan
Authors: Atherton David C.
Published: February 2025

Strange Tales from Edo: Rewriting Chinese Fiction in Early Modern Japan. By William D. Fleming. Harvard East Asian Monographs, vol. 465. Harvard University Asia Center, 2023. Pp. xii + 295. $49.95.
Review of The Betrayal of the Humanities: The University during the Third Reich
Authors: Beckman Gary
Published: February 2025

The Betrayal of the Humanities: The University during the Third Reich. Edited by Bernard M. Levinson and Robert P. Ericksen. Studies in Antisemitism. Indiana University Press, 2022. Pp. xx + 600. $40 (paper).
Review of Exploring Writing Systems and Practices in the Bronze Age Aegean
Authors: Nash Theodore
Published: February 2025

Exploring Writing Systems and Practices in the Bronze Age Aegean. By Philippa M. Steele. Contexts of and Relations Between Early Writing Systems, vol. 7. Oxbow Books, 2024. Pp. xxi + 169, illus. $80.
Co-existence of Untreated Chronic Lymphocytic Leukaemia and Acute Myeloid Leukaemia: A Rare Case of Synchronous Dual Haematological Malignancy
Authors: Sukumaran Renu , Nair Rekha A , Jayasudha AV , Sugeeth MT
Published: February 2025

The occurrence of Acute Myeloid Leukaemia (AML) or Myelodysplastic Syndrome (MDS) in patients with Chronic Lymphocytic Leukaemia (CLL) is rare. In most of the reported cases, AML occurs after treatment of CLL with cytotoxic drugs suggesting that AML may be a secondary leukaemia (therapy-related AML). AML or MDS occurring in untreated CLL patients is extremely rare with isolated case reports. Herein, we report the case of a 74-year-old male patient who was diagnosed four months back to have chronic B cell lymphoproliferative disorder, from an outside centre. The patient did not receive any treatment. Because of intermittent fever and increased fatigability, he came to our centre. Peripheral blood smear and bone marrow studies showed a dual population of atypical cells-one population of large immature cells with opened-up chromatin, prominent nucleoli, and another population of small atypical lymphocytes with clumped chromatin. Around 10% of immature cells showed Myeloperoxidase (MPO) positivity. Flow cytometric analysis also showed two separate populations of cells. The immunophenotype of one population was compatible with AML, with monocytic differentiation, and the second population showed features of CLL. A diagnosis of coexistent CLL and AML was given. The awareness of the co-existence of dual haematological malignancy, thorough morphological evaluation, and flow cytometric immunophenotyping will lead to accurate diagnosis of these combined malignancies.
Gestão do território e suas dinâmicas na região do Tapajós/PA
Authors: Benassuly Barros Márcio Júnior , Monteiro Raimunda Nonata , Nunes Pereira Izaura Cristina
Published: February 2025

O presente artigo é o resultado de pesquisa que teve como objetivo analisar a gestão do território e suas dinâmicas na área de influência da BR-163, em especial, nos municípios de Itaituba e Rurópolis, na região do Tapajós, estado do Pará, entre 2014 e 2020. Os procedimentos metodológicos adotados foram: pesquisa bibliográfico e documental; trabalho de campo e levantamento cartográfico. Os resultados da pesquisa indicam que, com o avanço do asfaltamento da BR-163 no estado do Pará e a instalação de várias estações de transbordo de cargas de grãos às margens do rio Tapajós (no município de Itaituba), a região vem passando, em pouco tempo, por profundas transformações. As conclusões do estudo indicam a necessidade de fortalecer os instrumentos de gestão e planejamento territorial, sobretudo, com atenção para a qualidade de vida da população dos municípios de Itaituba e Rurópolis.
Gestão dos resíduos sólidos de uma atividade mineradora: um estudo das operações da Vale em Corumbá/MS
Authors: Santo Anderson Luís , Cavalcante Ana Cecília Victorio
Published: February 2025

Os inúmeros acidentes ambientais que têm ocorrido recentemente vêm, em certa medida, promovendo a conscientização da sociedade sobre os impactos ambientais decorrentes dos processos produtivos, principalmente, das atividades que exploram os recursos minerais. Em consequência, uma série de leis e medidas protetivas vêm sendo criadas, visando encontrar meios que articulem a preservação ambiental e o crescimento econômico. Assim, este artigo busca examinar (através de levantamento bibliográfico, documental e entrevistas) a gestão dos resíduos sólidos gerados pela atividade da exploração mineral da Vale em Corumbá, no estado do Mato Grosso do Sul, evidenciando os impactos socioambientais causados pela atividade mineradora. Os resultados demonstram que, desde o acidente de Brumadinho/MG, a mineradora tem desenvolvido e implantado vários projetos que visam reduzir o impacto socioambiental de suas atividades. Alguns desses programas advêm do cumprimento de normas reguladoras, da legislação ambiental e da Política Nacional de Resíduos Sólidos.
Fragmentação produtiva regional e seus desdobramentos sobre o esvaziamento institucional da SUDENE: uma análise a partir das resoluções do CONDEL
Authors: Lopes Guilherme Carneiro Leão de Albuquerque , Macedo Fernando Cezar de
Published: February 2025

No século XXI prevalece, em relação à economia brasileira, um quadro de desindustrialização precoce e de especialização regressiva da pauta produtiva. As instituições e políticas voltadas ao desenvolvimento regional perdem prestígio na agenda política nacional. A Superintendência do Desenvolvimento do Nordeste (SUDENE), por exemplo, enfrenta dificuldades no seu papel de coordenação entre os entes subnacionais. O presente artigo se propõe a analisar a atuação da SUDENE com o objetivo principal de verificar sua estrutura de governança. Assume-se como hipótese que, diante do ciclo de acumulação voltado para a exportação de especialização produtiva, a autarquia passa por um processo de desmonte político e institucional. O artigo aponta para um movimento de esvaziamento normativo, político e financeiro, especialmente devido à debilidade do seu Conselho Deliberativo (CONDEL), agente principal no processo da tomada de decisão da política regional. A pesquisa seguiu dois caminhos metodológicos interligados: em primeiro plano, utiliza-se o método histórico-estrutural aplicado à análise regional e, de modo conjunto, realizam-se análises das deliberações contidas nas atas de reunião do CONDEL para investigar a lógica de atuação da Autarquia Federal.