bluuebunny/crossref_metadata_2025 huggingface dataset:
PREDICTORS OF RE-BLEEDING AFTER OESOPHAGEAL VARICEAL BANDING IN CIRRHOTIC PATIENTS AT 4 WEEKS
Authors: Shoaib Asghar  , Junaid Mustafa  , Habib ur Rehman  , Muhammad Kamran Farooq  , Muhammad Umar Waheed  , Salman Shahid
Published: May 2023

Background: Acute upper gastrointestinal bleeding is a serious complication in cirrhotic patients. Without recommended management, recurrent bleeding happens in 30-40% within the next 2-3 days, and up to 60% within 1 week. Aim was to determine predictors of re-bleeding after oesophageal variceal banding in cirrhotic patients for 4 weeks. It was a descriptive study, conducted at the Department of Medicine, Sheikh Zayed Hospital, Rahim Yar Khan. Six months from June 21 to December 21, 2021. Methods: A total of 93 patients with active oesophageal variceal bleeding were included in this study. Upper gastrointestinal (UGI) endoscopy was performed to look for bendable varices (grades 1-4) and band ligation was applied. Patients were followed for 4 weeks for the history of hematemesis or Malena, fall in haemoglobin of 2 grams per decilitre or more and endoscopic rebleeding findings. Results: Out of 93 patients, 67(72.0%) were males, while 26(28.0%) were females. The Mean age of the patients was 45.66±16.61 years. According to Child-Pugh Classification, the majority of the patients 45(48.4%) had Child-Pugh Class-A, while 33 (35.5%) were Child B and 15 (16.1%) patients belonged to Child-Pugh Class C. Red wale sign was noted in 22 patients (23.7%). Among 93 cirrhotic patients who presented with variceal bleeding, 9 (9.7%) had re-bleeding within 4 weeks. Amongst 9 patients, 8 patients (88.9%) had red wale sign, grade II or above oesophageal varices and belonged to severe liver disease with child class B or C. Conclusion: Endoscopic variceal band Ligation is an effective treatment modality for the control of oesophageal variceal bleeding. Re-bleeding after band ligation was 9.7%. The major contributing factors to re-bleeding were the severity of cirrhosis, grades and columns of oesophageal varices, number of bands ligation and findings of red wale sign. Increasing age and duration of cirrhosis were contributing predictors of increased re-bleeding risk
EFFECT OF COTTON DUST EXPOSURE ON RESPIRATORY HEALTH OUTCOMES AMONG TEXTILE WORKERS
Authors: Afreen Sadia  , Yousaf Ali  , Hasan Nawaz Tahir  , Natasha Shaukat  , Muhammad Irfan  , Nafees Asaad Ahmed
Published: May 2023

Background: Cotton dust is generated during various textile manufacturing processes. Only a few studies from Pakistan assessed cotton dust exposure and explored the relationship of duration of work in the textile industry with respiratory health outcomes. We aimed to assess cotton dust exposure and its association with lung function and respiratory symptoms among textile workers in Pakistan. Methods: We report findings from the baseline cross- sectional survey of the larger study, MultiTex, among 498 adult male textile workers from six mills conducted between Oct 2015-March 2016 in Karachi, Pakistan. Data collection included the use of standardized questionnaires; spirometry, and area dust measurements through UCB-PATS. Multivariable logistic and linear regression models were developed to assess the association of risk factors with respiratory symptoms and illnesses. Results: We found the mean age of workers to be 32.5 (±10) years; around 25% were illiterate. The prevalence of COPD, asthma, and byssinosis in our study was 10%, 17%, and 2%, respectively. The median cotton dust exposure was 0.33 mg/m3 (IQR;0.12-0.76). Increased duration of work among non-smokers was associated with a decline in lung function, FVC (-245 ml; 95% CI -385.71, -104.89) and FEV1 (-200 ml; 95 % CI -328.71, -84.11). Workers with certain job titles (machine operators, helpers, and jobbers), those with greater duration of work, and higher dust exposure, were more likely to report respiratory symptoms and illnesses. Conclusion: We report a high prevalence of asthma and COPD and a low prevalence of byssinosis. Cotton dust exposure and duration of employment were associated with respiratory health outcomes. Our findings highlight the need for preventive interventions in the textile industry in Pakistan.
CLINICAL RESULTS AFTER INTRA-CAVITARY DRAINAGE OF GIANT BULLAE IN PATIENTS WITH POOR PULMONARY RESERVES
Authors: Muhammad Shoaib Lodro  , Mazcuri Misauq , Tanveer Ahmad  , Ambreen Abid
Published: May 2023

Background: Giant bullae (GB) are space occupying lesions associated with chronic respiratory symptoms. The aim of this study is to evaluate outcome of intra-cavitary tube drainage procedures (ITDP) in terms of clinical and radiological benefits. Methods: A prospective study was conducted in The Department of Thoracic Surgery, Jinnah Postgraduate Medical Center, Karachi, from February 2021 to April 2022 after ethical approval. Patients above 12 years, with poor reserve and GB underwent clinical, radiological and laboratory assessment before and after ITDPs to document various studied parameters. Results: A total of 48 patients were included; thirty-two (66.7%) were males. Mean age was 46.7±12.14 years. Most common aetiology was COPD (28; 58.3%). GB were ‰¥10 cm in size in 36 (75%) with right upper lobe involvement in 20 (41.7%). Preoperative dyspnoea score of IV was seen in 41 (85.4%) and chest pain in 42(87.5%) patients. In 34(70.8%) patients, Monaldi procedure and in 14 (29.2%) Brompton technique was used. Dyspnoea score improved from grade IV to II (24/41; p=0.004) along with reduction in pain and cough (p=0.012; p=0.002), respectively. Improvement post operatively in oxygen saturation, forced vital capacity, forced expiratory volume in 1 sec (6.08±1.36%, 0.73±0.516 L and 0.57±0.07 L, respectively, p<0.001) was seen. Partial pressure of oxygen (PaO2) and carbon dioxide improved by 40.6±4.82 (p=0.009) and 13.22±3.62mmHg (p=0.7). Improvement of PaO2 was associated with reduction in the size of bullae (9.33±5.13cm; p=0.006). Radiographical resolution was seen in 41 (87.5%) majorly within 2 months (21; 51.2%). Duration of hospital stay was 4.20 ±0.92 days with no mortality. Complications were seen in 25 (52.1%) patients. Conclusion: intra-cavitary tube drainage procedures allow both clinical and physiological improvement in patients with GB. They allow resolution of bullae in patients with poor reserves and help in expansion of underlying compressed lung, improving both the clinical symptoms and radiological picture.
GANGLION IMPAR BLOCK FOR CHRONIC COCCYDYNIA
Authors: Malik Sara Haider , Khaleel Ahmad  , Liaquat Ali
Published: May 2023

Background: Coccydynia is also known as coccygodynia or coccygeal neuralgia. Coccyx is a triangular bone located within the vertebral column. The cause of coccydynia is unknown in the literature; however, it is found to be common among obese individuals, particularly females. The probability of women having coccydynia is five times higher than among men, which may result from larger pressure during pregnancy and child delivery. It is treated well with ganglion impar block. The aim of our study was to assess pain relief after Ganglion Impair Block with subsequent improvement in quality of life. Methods: A single-arm study was done in the department of Pain Medicine, Fauji Foundation Hospital, Rawalpindi from July 2021 to June 2022. A total of 50 patients with ‰¥3 months coccygeal pain of either gender aged between 20-60 years unresponsive to analgesics & anti-inflammatory medications with no laboratory abnormalities were included. Fluoroscopic guided trans-sacro'‘coccygeal ganglion impair block was done with alcohol neurolysis. The patients were observed for 1 hour in the recovery room to record post-intervention complications that may occur like hypotension, bradycardia, signs, and symptoms of cardiotoxicity or neurotoxicity etc. and evaluated for pain scores on the basis of the numeric rating scale (NRS). Data collected was analyzed using the statistical package for social scientists (SPSS) version 21. The quantitative data, i.e., age and NRS score were analyzed using mean and standard deviation and compared between pre and post-intervention periods. Results: The data from 50 patients who completed the follow-up period were used for analysis. The average age of the patients was 42.9±8.39 years, with a range of 38-60 years. Based on the data obtained, 30% of the patients experienced trauma (that is falling on the coccyx region). The mean score from NRS before intervention was 7.80±0.16 which decreased to 0.96±0.35, respectively, and this difference was statistically significant (p-value, <0.001). Conclusions: Ganglion Impar neurolysis is highly effective in the treatment of Chronic coccydynia.
THE PATIENTS' CHARACTERISTICS AND NON-SURGICAL TREATMENT RESULTS FOR HYPOPHARYNGEAL CANCER IN SOUTHEAST OF IRAN: A 13-YEAR STUDY
Authors: Larizadeh Mohammad Hasan , Aliasghar Arabi-Mianroodi  , Hadi Eslami
Published: May 2023

Background: Various modalities have been used to treat hypopharyngeal cancer. Non- surgical modalities include radiotherapy alone, sequential chemoradiation and concomitant chemoradiation or bio radiation. This study was conducted to evaluate the primary non-surgical treatment. Methods: A total number of 67 patients treated from March 2009 to January 2022 were enrolled in this study. The 2-year and 5-year survival rates were estimated using the Kaplan-Meier method. Log-rank test was used to compare the survival outcomes according to various factors. To define independent prognostic factors, we used Cox regression analysis. Results: The mean age of the patients was 56.2 years, and 55.2% of them were male. These patients were treated by radiation alone (9 patients) or induction chemotherapy followed by either radiation (4 patients), chemoradiation (33 patients), or bio-radiation (21 patients). The mean follow-up time was 18.12 months. The 2-year and 5-year overall survival rates were estimated to be 43% and 18%, respectively. Multivariate analysis showed that T stage, N stage, and treatment modality had a statically significant relationship with overall survival. Conclusion: The results of non-surgical treatment for hypopharyngeal cancer are not satisfactory. More studies are needed to investigate the role of salvage surgery.
LETHAL FUNGAL AORTITIS IN SURGICALLY CORRECTED SUPRAVALVULAR AORTIC STENOSIS IN A CHILD WITH WILLIAMS SYNDROME
Authors: Ayesha Butt  , Naela Ashraf  , Khuzaima Tariq  , Muneer Amanullah
Published: May 2023

Williams syndrome (WS), is a multisystem disorder occurring in 1 in 10,000 live births with supravalvular aortic stenosis (SVAS) being the most common cardiovascular manifestation. We present the case of a 2.5 years old male, known case of WS who presented with cognitive delay, history of right-sided stroke and left hemiplegia. Echocardiography revealed severe SVAS with a gradient of 105 mmHg. Diameter of the Sino tubular junction was 4 mm. Computerized tomography angiogram showed diffuse stenosis of ascending aorta with intraluminal thrombus. At surgery, the ascending aorta was augmented with autologous pericardial patches and end-to-end anastomosis of the proximal and distal aorta completed the reconstruction. The patient was discharged in a stable condition. He presented 6 weeks post-op with a pulsating pseudoaneurysm through the sternal wound. Emergency surgery with removal of fungal vegetation and reconstruction of the ascending aorta was performed. He expired due to fungal sepsis a week later.
Logging Crew Attributes by Region in the Southeast USA
Authors: Diniz Carlos , Smidt Mathew , Cooper Jason , Zhang Yaoqi
Published: May 2023

Urbanization, shrinking markets, and reduced forestry investment may affect harvesting efficiency in regions of the US South. To monitor these conditions, logging businesses have been tracked by surveys conducted by universities and trade associations. This project used a sampling approach coordinated with FIA utilization studies to sample logging crews based on a harvesting location. The approach was used to develop relationships among firm attributes and site attributes in six southeastern states (AL, GA, FL, NC, SC, and VA) from 2011 to 2018. The data included harvest attributes (location, harvest size and stand type) and logging firm attributes (production, crew labor, crew number, the number of machines by type, and machine age). For crew capital value, an equation was developed for this study using machine number and average machine age. The data from logging crews on 419 harvests were analyzed by region, harvest size, and stand type. Mean values for crew labor ranged from 3.1 to 7.1 workers. The average capital value per crew ranged from $220,000 to $524,000 per crew in the Coastal Plain with a narrower range in the Piedmont. In the Coastal Plain, higher productivity was detected for larger harvests and pine versus hardwood and mixed stands; however, in the Piedmont those trends were less obvious. Ratio of feller-bunchers, skidders and loaders were mostly 1:1:1 or 1:2:1 with 41% and 24% of samples, respectively. There were notable trends among Coastal Plain loggers regarding capital value and productivity with evidence supported by a production function. The differences in Piedmont (e.g., ownership size, market access, terrain, population density, etc.) may combine to limit daily production and labor productivity.
Efecto del nivel de proteina en la dieta sobre los indicadores de crecimiento de alevines del guanchiche (hoplias microlepis)
Authors: Rodríguez Tobar Jorge Magno , González Vélez Martin Armando , Vivas Moreira Luis Roque , Burgos Carpio Byron Andrés , García Martínez Antón Rafael
Published: May 2023

Es necesario explorar nuevas especies de peces destinadas a diversificar la oferta para contribuir con la seguridad alimentaria Ecuador cuenta con especies nativas que tienen un gran potencial en acuicultura. Se evaluó el efecto del porcentaje de proteína del alimento exógeno sobre el crecimiento de alevines de guanchiche (H. microlepis); Para tal efecto se utilizaron 1500 alevines de Hoplias microlepis de 1,5 g peso. La investigación experimental consistió en el manejo de variables en situaciones de control exhaustivo, en la provisión del alimento y el cálculo de los indicadores de crecimiento, Se utilizo 15 acuarios, provistos de aireación, recambio de agua del 30% cada día, 4 bombas de aire, con capacidad de salida de 2 l/seg, 100 alevines por cada acuario, se alimentó los alevines con balanceado comercial que contenía 24,32 y 40 % de proteína, durante 56 días; Los peces se pesaron cada 7 días. Resultados, el peso final fue 14,6±0,55; 10,4±0,55; 5,9±2,07, para los tratamientos que contenía 40,32 y 24 % de proteína en la dieta. se encontró diferencias significativas (p< 0.05) entre los niveles de proteína aplicados al experimento, el peso ganado ganancia de biomasa crecimiento absoluto y crecimiento especifico. En el presente estudio el porcentaje de proteína del alimento exógeno influyo sobre el crecimiento de alevines de guanchiche (H. microlepis).
Arteterapia jako forma wspomagania funkcjonowania spoecznego dziecka z autyzmem. Studium indywidualnego przypadku
Authors: Świderek Aleksandra , Kierzkowska Iryna
Published: May 2023

Artyku przedstawia analiz teoretyczn i empiryczn problematyki wykorzystania arteterapii we wspomaganiu funkcjonowania spoecznego dziecka z autyzmem. Na podstawie analizy teoretycznej (ujcie definicyjne pojcia arteterapii, funkcje i formy arteterapii oraz moliwoci wykorzystania arteterapii w pracy z dzieckiem ze spektrum autyzmu) skonstruowano i zrealizowano badanie majce na celu ustalenie stopnia i zakresu oddziaywa poszczeglnych form arteterapii na wspomaganie funkcjonowania spoecznego dziecka z autyzmem. Zwrcono uwag na intensywno i zakres oddziaywa takich form arteterapii jak muzykoterapia, choreoterapia, teatroterapia, ekspresja plastyczna, biblioterapia oraz formy czone (rysowanie wzorw graficznych do piosenek i rymowanek metod Dobrego Startu; wychwytywanie odgosw z otaczajcego wiata; zajcia rytmiki; chwytanie struktur palcami; stymulowanie polisensoryczne; wiczenia ruchu rozwijajcego metod W. Sherborne) w poszczeglnych obszarach funkcjonowania spoecznego dziecka, w ktrych najczciej w przypadku dzieci z autyzmem wystpuj trudnoci, czyli w zwizkach midzyludzkich, komunikacji i fantazji, repertuarze aktywnoci i zainteresowa.
Optimización de costos de producción, liquidez y solvencia en empresas bananeras: Estrategias clave.
Authors: Chusin-Cuzco María Fabiola , Peñaloza-López Verónica Leonor
Published: May 2023

La liquidez se refiere a la capacidad de una empresa para cumplir con sus deudas a corto plazo, considerando los plazos de vencimiento de dichas obligaciones. Por otro lado, la solvencia se relaciona con los activos disponibles para cumplir con las obligaciones de la empresa. En esta investigación, se aborda el problema del alto endeudamiento en Manobal Cía. Ltda., una empresa ubicada en Quevedo, causado por la variación en los costos de producción de banano, lo cual afecta su liquidez y solvencia. Con el objetivo de enfrentar esta problemática, se han diseñado estrategias de reducción de costos para mejorar la situación financiera de la empresa. El enfoque de la investigación es cualitativo y cuantitativo, de tipo no experimental, utilizando un método deductivo. Los resultados revelan que la entidad no ha implementado estrategias de control preventivo para mitigar el impacto negativo del COVID-19, lo cual ha afectado los costos en el proceso de producción durante la pandemia.
THE INFLUENCE OF WORKLOAD AND WORK STRESS ON EMPLOYEE PERFORMANCE AT PT ASURANSI JASA TANIA TBK
Authors: Adimulyo Nurcahyo , Ustria Mala Rora , Sudianto
Published: May 2023

The purpose of this research is to find outThe Influence of Workload and Work Stress on Employee Performance at Pt Asuransi Jasa Tania TbkIn 2021, the number of the Company's employees will be185 people. The following table below presents information regarding the composition of the Company's employees by gender, position and age. In 2021, the number of the Company's employees is 185 people. Based on research conducted at PT Asuransi Jasa Tania, Tbk Pekanbaru, it can be concluded that workload has an effect and is significant on the performance of employees of PT Asuransi Jasa Tania, Tbk, Work Stress has no effect and is not significant on employee performance at PT Asuransi Jasa Tania, Tbk. Workload and workload have a significant and significant effect on employee performance at PT Asuransi Jasa Tania, Tbk. These results explain that the dependent variable, namely performance (Y), can be explained by the independent variable, namely workload ( X1) and work stress (X2) with a value of 64
PENGEMBANGAN PRODUK BISNIS DALAM MENINGKATKAN OMSET PENJUALAN PADA POKDA IKAN PATIN
Authors: Yusuf Muhammad , Hidayat Rahmadani , Nusyirwan
Published: May 2023

Petani ikan patin di Kota Pekanbaru mengalami kendala dalam pengelolaan dan pemasaran ikan patin, dimana harga jual rendah, sedangkan biaya pengelolaan tinggi. Tujuan kegiatan ini untuk membantu petani ikan patin untuk meningkatkan pendapatan dan nilai jual patin yang dihasilkan melalui diversifikasi produk olahan ikan patin yang memiliki nilai jual tinggi. Diversifikasi produk olahan berbasis ikan patin sangat dibutuhkan untuk meningkatkan nilai tambah dan sekaligus meningkatkan perekonomian masyarakat petani ikan patin di Kel. Air Dingin kec. Marpoyan Damai Kota Pekanbaru Riau. Kegiatan yang dilakukan adalah: 1. variasi produksi olahan patin, mengingat ikan patin sangat melimpah, namun pengolahannya masih sangat kurang. Produk yang ditambahkan adalah abon, nugget, dan kerupuk iakn patin. 2. Pengemasan produk yang lebih menarik. 5. Perubahan strategi pemasaran. Ikan patin biasanya dijual pengepul atau ke pasar tradisional di Pekanbaru. Pemasaran yang dilakukan dengan cara menjual ke toko/supermarket, membuat brosur, dan memberi label agar kelihatan menarik. Hasil dari kegiatan ini adalah : 1. Meningkatnya pengetahuan dan kemampuan mitra tentang pembuatan varian olahan patin (nugget) 2. Adanya kemasan yang menarik, sehingga meningkatkan daya jual dan 3. Semakin luasnya daerah pemasaran
Dijital Bir İçerik Olarak Podcasting: Ulusal Radyoların Podcast Yayıncılığı Üzerine Bir İnceleme
Authors: AYDEMİR İsmail Mücahit , KODAK Dilge
Published: May 2023

Bu araştırmanın amacı Türkiye’de ulusal ölçekli karasal yayın yapan radyo istasyonlarının podcast yayıncılığına adapte olup olmadığını ortaya koymaktır. Bu çalışmada nitel araştırma yöntemlerinden doküman tarama yöntemi kullanılmıştır. Bu araştırma, Türkiye’de ulusal radyo yayın lisansı anlamına gelen R1 lisansına sahip olan radyo kuruluşları ile sınırlandırılmıştır. Bu çalışmaya Radyo ve Televizyon Üst Kurulu’nca (RTÜK) yayımlanan ‘‘R1-Ulusal Radyo Yayın Lisansına Sahip Kuruluşlar’’ listesinde yer alan radyo kuruluşları dahil edilmiştir. Bir radyo kuruluşunun sahip olduğu web site, mobil uygulama veya dahil olduğu başka özgün platform ya da platformlar, podcast yayıncılığını yapabilmesini sağlayan parametreler olarak belirlenmiştir. Bu parametreler doğrultusunda örneklem grubundaki radyo kuruluşlarının; kurumsal bir web site ve mobil uygulama sahibi olup olmadıkları, ayrıca farklı bir özgün platforma dahil olup olmadıkları incelenmiştir. Örneklem grubundaki radyo kuruluşlarının söz konusu dijital ortamlarda podcast içerikleri yayınlayıp yayınlamadıkları tespit edilmiştir. Bu araştırma kapsamında aynı zamanda örneklem grubundaki radyo kuruluşlarının, küresel ölçekte popüler olan Spotify, Apple Podcast, Google Podcast isimli podcast platformlarında yer alıp almadıkları da analiz edilmiştir. Bu araştırma, son yıllarda küresel ölçekte popüler hale gelen podcast yayıncılığına, Türkiye’de ulusal ölçekte karasal yayın yapan konvansiyonel radyo istasyonlarının adapte olup olmadığını ortaya koyması bakımından önem arz etmektedir. Podcast içerikleri üreten bireysel ve kurumsal yayıncıların ortaya çıktığı günümüzde, her gün sesli içerikler üreten ve yayınlayan radyo kuruluşlarının, mevcut içeriklerini internet ortamında ‘arşiv’ veya ‘podcast’ başlığı altında yeniden yayınlayıp yayınlamadıkları konusu, bu çalışmanın temel problemini oluşturmaktadır. Bu araştırmanın sonucunda elde edilen verilere göre: Türkiye’deki ulusal radyoların nerdeyse yarısının 5 adet özgün medya platformu içerisine dahil olduğu tespit edilmiştir. Türkiye’deki ulusal radyoların ‘podcast’ kavramına ilgisiz kalmadığı ve söz konusu dijital yayıncılığa adapte olmak için alternatif çalışmalar yaptıkları görülmüştür.
Avaliação dos transtornos ansiosos e alimentares nos estudantes de medicina da UNAERP de 2021 a 2022
Authors: Freitas Valdomiro Sampaio de , Faria Júnior Milton , Banzatto Sofia , Cantieri Nathalie Cristina , Rodrigues Júlia Nakao
Published: May 2023

A compulsão alimentar (CA) é caracterizada pela ingesta exagerada de comida em um curto período de tempo e de forma descontrolada, porém sem a adoção de medidas compensatórias para impedir o ganho ponderal. Os indivíduos com histórico de transtorno alimentar, por sua vez, tendem a uma personalidade mais ansiosa. É sabido, entretanto, que a ansiedade é um estado emocional fisiológico desde que as preocupações não ocupem a maior parte do dia do indivíduo, como nos transtornos ansiosos generalizados (TAG). Com o objetivo de combater esses pensamentos ansiosos obsessivos, a pessoa opta por algumas medidas de escape, sendo que na maior parte dos casos a descarga psicológica é descarregada na ingesta patológica de alimentos. Dessa forma, observa-se como consequência comum de ambas as desordens o risco elevado da obesidade, que tem impacto negativo na saúde e na qualidade de vida. Frente a isso, o presente estudo objetiva avaliar a comorbidade entre ambos os transtornos psíquicos, tendo como público alvo acadêmicos de medicina da Universidade de Ribeirão Preto (UNAERP), para que com os resultados possamos despertar o interesse nessas áreas de estudo e assim gerar uma promoção e prevenção de saúde, evitando, por exemplo, a obesidade que é altamente prevalente em ambas as patologias e além disso, um fator de risco para doenças crônicas, principalmente as cardiovasculares, que além de afetar a qualidade de vida do doente é uma ameaça socioeconômica.
Evaluation of sleep quality, excessive daytime sleepiness and associated factors in medical students - a systematic review
Authors: De Martin Almeida Rodrigo , Resende Neiva Andreza , Ribeiro Zago Isabella , Eduardo Guimarães Macedo Miguel
Published: May 2023

Objective: To systematically review the scientific literature from the last 20 years about the EDS and Medical Students dyad, in order to understand the relationship and the impacts on the health of these individuals. Methods: A systematic review was conducted in December 2020 in PubMed and SciELO using the descriptors "Sleep Disorders", "Excessive Daytime Sleepiness" (EDS) and "Medical Students". Inclusion criteria were: original articles from the last 20 years, in English, Portuguese and Spanish, and, as exclusion criteria, failure to meet inclusion eligibility. Result: The analysis of the studies demonstrates a direct relationship between the academic responsibilities of medical students and sleep deprivation. As a consequence, this course presents itself as a trigger of poor sleep quality indices and EDS, as well as social and psychological consequences for academics. Conclusion: The great demands of the medical course may lead to sleep disorders due to the difficulty in reconciling them with individual health, causing psychopathological symptoms and mental exhaustion. Thus, measures that balance the student's routine with academic needs are important.
 
DOI: 10.56238/isevmjv1n2-005
ANALISIS PENGETAHUAN MASYARAKAT TERHADAP KETEPATAN PENGGUNAAN MULTIVITAMIN DI MASA PANDEMI DI KELURAHAN LENTENG AGUNG JAKARTA SELATAN
Authors: Zuzana Zuzana , Putri Setiawan Deasy
Published: May 2023

ABSTRAK

 

Virus corona Disease 2019 (COVID-19) adalah penyakit jenis baru yang belum pernah diidentifikasi sebelumnya pada manusia dengan tanda dan gejala antara lain gejala gangguan pernapasan akut seperti demam, batuk dan sesak napas, masyarakat berupaya agar dapat terhindar dari penularan virus COVID-19 salah satunya adalah dengan meningkatkan daya tahan tubuh dengan mengkonsumsi multivitamin. Tujuan penelitian ini adalah untuk mengetahui adanya hubungan antara usia, jenis kelamin, tingkat pendidikan, pekerjaan dan pendapatan terhadap tingkat pengetahuan masyarakat mengenai multivitamin. Metode penelitian ini menggunakan desain cross sectional. Sampel yang digunakan seluruh populasi yaitu sebanyak 263 responden. Analisis data menggunakan program SPSS versi 22. Hasil penelitian menujukkan sebagian besar responden merupakan berada pada rentang usia 20-35 tahun sebanyak 178 responden (67,7%), jenis kelamin perempuan sebanyak 161 responden (61,2%), pendidikan terakhir SMA/Sederajat sebanyak 178 responden (67,7%), pekerjaan pegawai swasta sebanyak 117 responden (44,5%) dan pendapatan tinggi Rp.2.500.000-Rp.3.500.000 perbulan sebanyak 94 responden (35,7%). Hasil analisis univariat didapat mayoritas masyarakat termasuk dalam kategori cukup sebanyak 104 responden (39,5%). Hasil analisis bivariat menunjukkan terdapat hubungan pada tingkat pendidikan, pekerjaan dan pendapatan dengan tingkat pengetahuan mengenai multivitamin sedangkan tidak terdapat hubungan antara usia dan jenis kelamin terhadap tingkat pengetahuan multivitamin.
PERSEPSI MASYARAKAT TERHADAP OBAT TRADISIONAL UNTUK MENCEGAH COVID-19 DI KABUPATEN PASAMAN BARAT KECAMATAN LUHAK NAN DUO
Authors: Reslina Isra , Syofyan Syofyan , Raharjo Budi , Elvina Ridha
Published: May 2023

ABSTRAK

 

Obat tradisional adalah bahan atau ramuan bahan yang berupa bahan tumbuhan, bahan hewan, bahan mineral, sediaan sarian (galenik) atau campuran dari bahan tersebut yang secara turun menurun telah digunakan untuk pengobatan dan dapat diterapkan sesuai dengan norma yang berlaku di masyarakat. Pengunaan obat tradisional meningkat selama pandemi Covid-19 seiring dengan meningkatnya kesadaran masyarakat akan pentingnya meningkatkan imunitas tubuh. Penggunaan obat tradisional digunakan sebagai upaya pemeliharaan kesehatan, pencegahan penyakit, dan perawatan kesehatan terkait pemanfaatan tanaman obat berupa obat tradisional Indonesia pada masa kedaruratan kesehatan masyarakat dan atau bencana nasional Coronavirus Disease 2019. Penelitian ini bertujuan untuk mengetahui persepsi masyarakat terhadap obat tradisional untuk mencegah Covid-19 serta untuk mengetahui hubungan antara karakteristik sosiodemografi dengan persepsi masyarakat terhadap obat tradisional untuk mencegah Covid-19 di Kecamatan Luhak Nan Duo Kabupaten Pasaman Barat. Penelitian dilakukan pada bulan April - Mei 2021 pada masyarakat yang sedang berada di rumah. Penelitian dilakukan menggunakan metode survei lapangan (observasi) menggunakan kuesioner tervalidasi. Pengisian kuesioner dilakukan oleh 100 responden yang memenuhi kriteria inklusi yang telah ditetapkan dengan menggunakan metode purposive sampling. Data yang diperoleh dianalisis menggunakan uji chi square. Hasil penelitian menunjukkan persepsi masyarakat terhadap obat tradisional untuk mencegah Covid-19 adalah baik (98%). Dapat disimpulkan dari hasil uji chi square tidak terdapat hubungan signifikan antara karakteristik sosiodemografi dengan persepsi masyarakat terhadap obat tradisional untuk mencegah Covid-19 (p > 0,05).
Europium doped titanium dioxide nanocrystalline: synthesis, structure and optical properties
Authors: Adriss I. A. S. , Shabanb F. , Yagoube M. Y. A. , Wardia H. , Issa Nashwa A. , Abuelhassanb Hassan H. , Journal Albaydha University
Published: May 2023

Abstract

Uniform, spherical-shaped TiO2: Eu nanoparticles with different doping concentrations were synthesized using the sol-gel method. The structural, morphology, optical, luminescent, and surface properties of the samples were investigated at different Eu3+ concentration. The morphology, crystalline structure, and chemical composition of the samples were characterized by scanning electron microscopy, X-ray diffraction, and X-ray photoelectron spectroscopy. The X-ray diffraction results reveal that the obtained powder nanoparticles consist of a single phase tetragonal structure. The crystallite sizes calculated by utilizing Scherrer’s equation were found in the range of 18.94 – 7.77 nm for TiO2:Eu samples annealed at 550οC. The SEM images reveal an irregular agglomerated morphology indicating a decrease in particle size with an increase in Eu3+ concentration. X-ray photoelectron spectroscopy (XPS) high resolution spectra of the Ti-2p peak confirmed that Ti atoms were in a doubly ionized state, and the deconvolution of the O1s XPS peak show the presence of oxygen related defects in the sample. EDS results confirm a systematic increase of Eu content in the as-prepared samples with the increase of europium concentration. Incorporation of europium in the titania particles induces a structural deformation and a blueshift of their absorption edge. The luminescence intensity increases with Eu3+ concentration up to 3 mol% and then quenched. While the PL emission of the as-grown samples is dominated by the 5D0 - 7Fj transition of Eu3+ ions, the emission intensity reduces drastically after thermal annealing due to outwards segregation of dopant ions.

Keywords: Titanium dioxide; Photoluminescence Spectroscopy; XPS; Nanocrystalline; Anatase; Rutile.
Fitrah Dalam Al-Qur’an Dan Harmonisasinya Dengan Pendidikan
Authors: Ansor dan Abu Anwar
Published: May 2023

Al-Qur’an adalah kitab yang diturunkan Allah SWT kepada Nabi Muhammad SAW sejak 14 abad yang lalu sampai sekarang, berisi petunjuk dan pedoman hidup bagi umat manusia. Al-Qur’an juga memiliki banyak isyarat dan solusi dalam mengarungi kehidupan. Manusia sebagai hamba sekaligus juga khalifah di bumi, Allah jelaskan dalam Al-Qur’an memiliki Fitrah, anugrah Allah yang ditanamkan secara rahasia. Kata Fitrah dalam Al-Qur’an diualang sebanyak 20 kali dalam berbagai bentuk, dan tidak hanya bermakna Suci atau penciptaan.
Penafsiran Da'i Dalam Tafsir Al-Azhar
Authors: Rengga Irfan
Published: May 2023

Tulisan ini bertujuan untuk memaparkan bagaimana penafsiran buya Hamka dalam membahas ayat-ayat da'wah yang berbicara seputar da'i dengan menggunakan metode tafsir tematik (maudhu'i). Metode penelitian yang digunakan adalah metodologi kepustakaan (library research) yang bersifat kualitiatif serta memakai metode analisa isi (content analysis) dalam menganalisa ayat-ayat da'wah yang berkaitan dengan da'i tersebut. Adapun hasil penelitian ini adalah pertama, Hamka mengatakan ada sebelas syarat yang harus dimiliki oleh seseorang yang menekuni bidang dakwah.

Kemudian, tiga metode dakwah dalam Alquran, yaitu: dakwah dengan kebijaksanaan, dakwah dengan nasehat yang baik dan membantah/mendebat dengan sopan. Kedua, Terdapat beberapa langkah yang dilakukan buya Hamka ketika menafsirkan ayat-ayat seputar da'i, yaitu: Mengambil sumber dari nash dan dalil aqli. Memberikan sub-judul pada tafsirannya. Sedikit memberikan penjelasan makna suku kata dalam ayat. Menerangkan hubungan suatu ayat dengan ayat sebelumnya. Memuat kisah inspiratif. Ketiga, ada enam karakteristik da'i yang muncul pada tafsiran buya Hamka yaitu: Memiliki kesadaran beragama, punya wawasan yang luas, pribadi yang kuat, memiliki budi pekerti yang luhur, tidak mengharapkan imbalan, dan memiliki jiwa persatuan.
EKSISTENSI WALI DALAM AKAD PERNIKAHAN PERSPEKTIF TEORI DOUBLE MOVEMENT FAZLUR RAHMAN
Authors: Irawan Ah. Soni
Published: May 2023

Eksistensi wali dalam akad pernikahan sampai saat ini masih menjadi perdebatan diantara fuqoha’, sebab tidak ada ayat al-Quran yang jelas secara ibarat al-nash menghendaki adanya wali dalam akad pernikahan. Jumhur ulama berpendapat bahwa keberadaan wali nikah merupakan syarat dan rukun sahnya suatu akad pernikahan, akibatnya perempuan tidak boleh dan tidak sah secara hukum apabila menikahkan dirinya sendiri tanpa restu walinya meskipun ia telah dewasa. Sedangkan menurut madzhab Imam Abu Hanifah perempuan yang sudah dewasa boleh dan sah menikahkan dirinya sendiri tanpa harus izin walinya, selama perempuan tersebut menikah dengan pasangan yang sekufu, bahkan menurutnya kehadiran wali dalam proses akad nikah sebatas pada hukum mustahab (disenangi), sehingga keberadaan wali tidak berpengaruh pada keabsahan akad nikah. Masing-masing pandangan yang dikemukakan oleh keduanya berdasar, baik secara ijtihad ushul linguistik (qat’iyyah dilalah) maupun rasional (al-qat al-mantiqi). Menghadapi problematika hukum yang masih diperdebatkan tersebut, penulis mencoba untuk mensinergikan antara dalil naqli dan dalil aqli serta  memahami keaslian historis (qat’iyyah al-tsubut) kemudian dikontekstualisasikan dengan kondisi saat ini, sehingga kajian pembahasanya lebih komperhensif (holistik), tidak lagi atomistik (hanya sebatas pendapat satu atau dua ulama madzhab). Penelitian ini bertujuan untuk mendeskripsikan eksistensi wali nikah dalam proses akad nikah dengan tinjauan teori double movement (gerak ganda), sebagai langkah upaya untuk mendorong umat Islam agar mendayagunakan pemikiran akalnya (ra’yu), penalaran analogis (qiyas), serta penalaran hukum (ijtihad) dalam rangka menelaah kembali hadis nabi tentang keberadaan wali dalam akad pernikahan yang menjadi perdebatan di kalangan ahli fikih untuk dikontekstualisasikan sesuai dengan situasi dan kondisi sosial saat ini.
Peran Lembaga Pembiayaan Syariah dalam Mempercepat Pemulihan UMKM di Masa Pandemi
Authors: Nasution Lokot Zein
Published: May 2023

Covid-19 pandemic has not only impacted the health sector, but also social, political, security, and especially the economic sector. Various empirical studies prove that the Covid-19 pandemic has significantly reduced market demand due to social activities and trade transactions. SMEs are one of the most powerful business actors, and a threat to business in the long term. The source of the problem is the low accessibility of financing, including the non-optimal use of sharia financing during the pandemic. how this can be done to find and explore Islamic financing institutions that can be done in the recovery of pandemic MSMEs. Based on a review of the study literature, it was found that Islamic financing has advantages in the form of the principle of risk sharing to overcome the vulnerability of SMEs businesses. Another advantage lies in sharia guidelines that are in accordance with democracy, and the application of the precautionary principle. In Islamic financing, there is no party who benefits above the loss of the other party, and there is no unilateral or repressive treatment to other parties. The advantage it has is that Islamic financing must be conditioned to suit business needs, equipped with an empowerment model as part of the SMEs financing scheme. For this reason, the government needs to encourage the Islamic finance ecosystem as a foundation in developing Islamic financing institutions for the recovery of SMEs during the pandemic.
Towards Sustainable Food Security in Jakarta: Assessing the Effectiveness of Supporting Systems and Identifying Pathways for Improvement
Authors: Dewi Marulina
Published: May 2023

This research conceptual paper aims to explore the current state of food security in Jakarta and assess the effectiveness of supporting systems in ensuring sustainable food access, availability, and utilization. The study examines the interplay of various factors, including agricultural practices, distribution networks, market mechanisms, and policy frameworks, to evaluate their impact on food security outcomes in Jakarta. Through a comprehensive analysis of existing literature, empirical data, and stakeholder perspectives, this paper identifies key challenges and proposes pathways for improving the supporting systems to achieve sustainable food security in Jakarta.
Hambatan Pelaksanaan Program Directly Observed Treatment Short-Course (DOTS) Di Negara Berkembang: Sebuah Tinjauan Sistematik
Authors: Venia Oktafiani
Published: May 2023

Tuberculosis is a global burden with most cases occurring in developing countries. After the implementation of Directly Observed Treatment Short-course (DOTS), the incidence of tuberculosis decreased. Despite, studies reported constraints in implementing this program. This study aims to describe the challenges of DOTS implementation in developing countries narratively. Methods: a search strategy through PUBMED was used to identify relevant articles. 10 relevant articles were included from 349 records. The studies were conducted in 8 developing countries namely South Africa, Sub-Saharan Africa, Brazil, Ethiopia, Indonesia, Angola and Nigeria. All articles included was extracted and categorized in ten main points regarding the challenges of the implementation of DOTS program. Results: There were 10 main points of challenges in implementing the DOTS strategy in developing countries : lack of access to health centres, managerial and organizational service problems, lack of health education-related tuberculosis, lack of supervision, TB co-infection, lack of trained health workers, smoking, alcohol, and drug abuse during treatment, patient-health professional relationship, lack of food availability and interruption during treatment. Conclusion: The implementation of the DOTS strategy encounters many challenges in developing countries where lack of health facilities, managerial and organizational service problems and lack of education-related TB are the main challenges to implement the program
FAKTOR YANG MEMPENGARUHI MUTU PELAYANAN KEPERAWATAN SELAMA MASA PANDEMI COVID-19 DI RSUD DR. HASRI AINUN HABIBIE PROVINSI GORONTALO
Authors: Arifin Umar  , Firmawati Firmawati  , Cicin S. Kodu  , Rimawati Polontalo
Published: May 2023

Mutu pelayanan kesehatan ialah derajat kesempurnaan pelayanan kesehatan yang diselenggarakan sesuai standar pelayanan yang telah berlaku. Penelitian ini bertujuan untuk mengetahui faktor-faktor yang berhubungan dengan mutu pelayanan kesehatan.  Desain penelitian yaitu deskriptif dengan rancangan cross sectional. Hasil penelitian menunjukkan bahwa  tidak ada hubungan antara Tangible dengan mutu  pelayanan, ada hubungan antara Reability dengan mutu pelayanan, ada hubungan antara responsiveness dengan mutu pelayanan, tidak ada hubungan antara Emphaty  dengan mutu pelayanan, ada hubungan antara Assurance dengan mutu pelayanan. Sehingga bisa di simpulkan adanya pengaruh antara Reability, Responsiveness, Asurance dengan mutu pelayanan kesehatan selama masa pandemi covid 19.
Hubungan Penggunaan Gadget Dengan Perkembangan Psikososial Pada Anak Usia Prasekolah di TK Raudhatul Atfhal Assalam Manado
Authors: Siska Dauwango  , Irma M. Yahya  , Sri Wahyuni
Published: May 2023

Latar Belakang Penggunaan gadget bagi perkembangan anak usia dini dapat memberikan dampak positif dan dampak negatif. Anak yang terbiasa menggunakan gadget secara berlebihan akan berdampak pada perkembangan psikososialnya. Tujuan Penelitian diketahui hubungan penggunaan gadget dengan perkembangan psikososial anak usia prasekolah di TK Raudhatul Athfal Assalam Manado. Metode Peneltian menggunakan Deskriptif Analitik dengan rancangan Cross Sectional. Sampel dalam penelitian ini sebanyak 60 orang menggunakan total sampling. Hasil Penelitian Dari hasil uji Chi-Square with Continuity Correction  menunjukan ada hubungan antara penggunaan gadget dengan perkembangan psikososial pada anak usia prasekolah di TK Raudhatul Athfal Assalam Manado nilai p-value = 0,001 ≤ 0,05. Kesimpulan dalam penelitian ini ada hubungan penggunaan gadget dengan perkembangan psikososial anak usia prasekolah di TK Raudhatul Athfal Assalam Manado. Saran orang tua untuk lebih selektif lagi dalam memberikan mainan kepada anak dan perlu adanya pengawasan serta ketegasan dalam memberikan batasan kepada anak dalam bermain gadget.
Pengaruh Edukasi Tentang Penyakit Tb Paru Terhadap Sikap Penerimaan Anggota Keluarga yang Menderita TB Paru di Poliklinik TB DOTS (Directly Observed Treatment Short-Course) RSU GMIM Pancaran Kasih Manado
Authors: Sandra Wowiling  , Rahmat H. Djalil  , Faradilla M. Suranata
Published: May 2023

Tuberkulosis paru (TB paru) adalah suatu penyakit infeksi menular yang disebabkan oleh bakteri Mycobacterium tuberculosis. Sebagian besar kuman Tuberkulosis menyerang paru, tetapi dapat juga mengenai organ tubuh lainnya. Kuman ini berbentuk batang dan mempunyai sifat khusus yaitu tahan terhadap asam pada pewarnaan. Tujuan penelitian ini untuk mengetahui pengaruh edukasi tentang penyakit TB Paru terhadap sikap penerimaan anggota keluarga yang menderita TB Paru di Poliklinik TB DOTS (Directly Observed Treatment Short-Course) RSU GMIM Pancaran Kasih Manado.
Penelitian dilakukan dengan menggunakan desain penelitian Eksperimen dengan pendekatan divasi Experimen Pre test – post test group. Sampel diambil dengan menggunakan teknik pengambilan sampel Total Sampling dimana mencakup seluruh pasien yang menderita TB Paru di Poliklinik DOTS RSU GMIM Pancaran Kasih Manado, yaitu sebanyak 30 orang. Pengumpulan data dilakukan dengan cara memberikan kuesioner dan observasi. Selanjutnya data diolah dengan menggunakan bantuan komputer program SPSS versi 16,0 untuk di analisa dengan uji statistic McNemar dengan tingkat kemaknaan (α) 0,05.
Hasil penelitian menunjukkan bahwa sebagian besar responden memiliki sikap baik yaitu 29 responden (96,7%), dengan nilai p = 0,002. Nilai p < α = 0,05, maka Ha diterima,
Kesimpulan dalam penelitian ini yaitu terdapat pengaruh edukasi tentang penyakit TB Paru terhadap sikap penerimaan anggota keluarga yang menderita di Poliklinik TB DOTS (Directly Observed Treatment Short-Course) RSU GMIM Pancaran Kasih Manado. Penulis menyarankan agar pasien dan keluarga lebih banyak lagi mencari informasi tentang penyakit Tb Paru baik melalui media massa, media cetak maupun melalui edukasi dari petugas kesehatan. Sehingga penulis mengharapkan pasien dan keluarga mengerti dan memahami serta dapat mengimplementasikannya didalam kehidupan sehari-hari.
Pengaruh Edukasi Terhadap Keterampilan Keluarga Dalam Penanganan Tersedak (Choking) Pada Anak di Lingkungan IV Kelurahan Bailang Kecamatan Bunaken Kota Manado
Authors: Alfin Sanggilalung  , Faradilla Miftah Suranata  , Silvia Dewi  Mayasari Riu
Published: May 2023

Latar Belakang : Tersedak (Choking) adalah tersumbatnya saluran jalan napas akibat benda diluar tubuh secara total atau parsial, sehingga menyebabkan korban sulit bernapas, dan menyebabkan kekurangan oksigen. Tujuan : Tujuan penelitian ini mengetahui “Pengaruh Edukasi Terhadap Keterampilan Keluarga Dalam Penanganan Tersedak (Choking) pada Anak di Lingkungan IV Kelurahan Bailang Kecamatan Bunaken”. Metode Penelitian : Penelitian ini menggunakan metode penelitian Quasi Eksperimen dengan rancangan One group Pretest –Posttest Design. Sampel responden dalam penelitian ini sebanyak 56 orang dengan tehnik pengambilan sampel Total Sampling. Pengumpulan data menggunakan lembar observasi. Di analisa dengan uji statistik Mc.Nemar. Hasil Penelitian : Dari hasil Uji statistik Mc.Nemar menunjukan ada pengaruh yang bermakna antara edukasi terhadap keterampilan keluarga dalam penanganan tersedak (choking) pada anak di Lingkungan IV Kelurahan Bailang (p) = 0,000; α = 0,05. Kesimpulan : Kesimpulan dalam penelitian ini terdapat Ada pengaruh edukasi terhadap keterampilan keluarga dalam penanganan tersedak (choking) pada anak di lingkungan IV kelurahan bailang kecamatan bunaken. Saran : Diharapkan dapat menjadi acuan untuk  instansi kesehatan dan pendidikan dalam upaya pemberian edukasi kesehatan kepada masyarakat dalam upaya menangani masalah kesehatan yang mengancam nyawa pada masyarakat.
Uji Aktivitas Antibkteri Ekstrak Etanol Daun Kemangi (Ocium Sanctum L) Asal Desa Ureng Kabupaten Maluku Tengah Terhadap Pertumbuhan Bakteri Staphylococcus epidermis
Authors: Amelia Niwele  , Aulia Debby Pelu  , Laitupa Hardiyanti L
Published: May 2023

One of the plants that can use drugs is the (Ocimum Sanctum Linn). Basil leaves are one of the many available and readily available natural plants in Asia such as Indonesia.In addition to using it as fly,basil leaves are used as bronchitis,malaria,diarrhoea,skin disease,and so on.Studies have been conducted on the test of the leaf’s antibacterial ethanol (Ocimum Sanctum Linn) for the growth of the staphylococcus epidermis bacteria by using the diffusion method for the commonwealth.The study is to identify the extract of basil leaf ethanol (Ocimum Sanctum Linn) that gives resistance to bacteria. Basil leaves (Ocimum Sanctum Linn) in extraction by means 0f a 96% ethanol solducer. The results of the extraction are then in the screening of antibacterial activity at a concentration 25%,50%,and 100%.  Tests obtained indicate that ethanol extract is 96% of basil leaves (Ocimum Sanctum Linn) cannot prevent the growth of the staphylococcus epidermis bacteria. The false factor derived from the powdered leaf ethanol extract (Ocimum Sanctum Linn) is influenced by mildew suspension,milquetide exposure to media,incubation temperatures,incubation times,media thickness,and media composition.
Uji Aktivitas Antidiabetes Ekstrak Etanol Daun Pala (Myiristica Fragrans) Terhadap Tikus(Rattus Norvegicust) Galur Wistar Jantan Yang Diinduksi Aloksan
Authors: Aulia Debby Pelu  , Pia Batmomolin  , Salama Nurlette
Published: May 2023

Nutmeg is known as a spice plant that has economic value and multipurpose because every part of the plant can be used in various industries. Compounds contained in nutmeg leaves include alkaloids, triterpenoids, tannins and 2 flavonoids. The purpose of this study was to determine the antidiabetic effect of ethanolic extract of nutmeg leaf (myristica frangrans) against male wistar white rats (Rattusnorvegicus) induced by alloxan administered intraperitoneally and compare its effectiveness with glibenclamide. This study used five treatment groups, namely the administration of aquadest as a negative control, glibenclamide as a positive control and ethanol extract of nutmeg leaves at a dose of 100 mg/kg BW, 200 mg/kg BW and 300 mg/kg BW as control treatments. Blood glucose measurements were carried out on day 0 (three days after induction), day 3, day 7 and day 10. The results showed that the ethanol extract of nutmeg leaf (myristica frangrans) TEST ACTIVITY can reduce blood glucose levels. At a dose of 300 mg/kg but not exceeding the decrease in blood sugar in the administration of glibenclamide. Giving ethanol extract of nutmeg leaves (myristica frangrans) also has activity to repair damage to pancreatic -cells in white rats (Rattus norvegicus) induced by alloxan.