bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figure 4 from NEDD9 Regulates Actin Dynamics through Cortactin Deacetylation in an AURKA/HDAC6–Dependent Manner
Authors: Kozyreva Varvara K. , McLaughlin Sarah L. , Livengood Ryan H. , Calkins Robin A. , Kelley Laura C. , Rajulapati Anuradha , Ice Ryan J. , Smolkin Matthew B. , Weed Scott A. , Pugacheva Elena N.
Published: April 2023

PDf - 35K, Supplementary Figure 4. F-actin pull down assay using lysates from MDA-MB-231 cells expressing shCon, shCTTN and shHDAC6 (HD6) as in Fig.4B (shCon, shHD6). Representative images of WB analysis of F-actin precipitates (P) and supernatant (S) fractions with anti-CTTN and -actin antibodies. Experiment was performed three times.
Supplementary Methods from Novel Potent and Selective Inhibitors of p90 Ribosomal S6 Kinase Reveal the Heterogeneity of RSK Function in MAPK-Driven Cancers
Authors: Aronchik Ida , Appleton Brent A. , Basham Stephen E. , Crawford Kenneth , Del Rosario Mercedita , Doyle Laura V. , Estacio William F. , Lan Jiong , Lindvall Mika K. , Luu Catherine A. , Ornelas Elizabeth , Venetsanakos Eleni , Shafer Cynthia M. , Jefferson Anne B.
Published: April 2023

PDF file - 166K
Table S11 from Metabolic Profiling in Formalin-Fixed and Paraffin-Embedded Prostate Cancer Tissues
Authors: Cacciatore Stefano , Zadra Giorgia , Bango Clyde , Penney Kathryn L. , Tyekucheva Svitlana , Yanes Oscar , Loda Massimo
Published: April 2023

Metabolite statistical analysis of the differences between normal and tumor prostate tissues.
Table S1 from Metabolic Profiling in Formalin-Fixed and Paraffin-Embedded Prostate Cancer Tissues
Authors: Cacciatore Stefano , Zadra Giorgia , Bango Clyde , Penney Kathryn L. , Tyekucheva Svitlana , Yanes Oscar , Loda Massimo
Published: April 2023

Analysis of the metabolites found and missed in FFPE cell samples categorized by superclass, class, subclass, substituent, physical/chemical properties, and pathways.
Supplemental Table 2 from A Genome-Wide Loss-of-Function Screen Identifies SLC26A2 as a Novel Mediator of TRAIL Resistance
Authors: Dimberg Lina Y. , Towers Christina G. , Behbakht Kian , Hotz Taylor J. , Kim Jihye , Fosmire Susan , Porter Christopher C. , Tan Aik-Choon , Thorburn Andrew , Ford Heide L.
Published: April 2023

Supplemental Table 2: GSEA analysis for upregualted (enriched) pathways in TRAIL treated BJAB-LEXR vs. BJAB WT
Supplemental Materials from Increased Expression of System xc− in Glioblastoma Confers an Altered Metabolic State and Temozolomide Resistance
Authors: Polewski Monika D. , Reveron-Thornton Rosyli F. , Cherryholmes Gregory A. , Marinov Georgi K. , Cassady Kaniel , Aboody Karen S.
Published: April 2023

Complete list of Gene Ontology categories. Supplementary Table 1: Read mapping statistics. Supplementary Table 2: Full list of Gene Ontology categories enriched in genes upregulated upon SLC7A11 overexpression. Supplementary Table 3: Full list of Gene Ontology categories enriched in genes downregulated upon SLC7A11 overexpression. Supplementary Table 4: Full list of Gene Ontology categories enriched in genes upregulated upon SLC7A11 knock down. Supplementary Table 5: Full list of Gene Ontology categories enriched in genes downregulated upon SLC7A11 knock down.
Supplementary Table 5 from A Monotonic and Prognostic Genomic Signature from Fibroblasts for Colorectal Cancer Initiation, Progression, and Metastasis
Authors: Berdiel-Acer Mireia , Cuadras Daniel , Díaz-Maroto Natalia Guillén , Sanjuan Xavier , Serrano Teresa , Berenguer Antoni , Moreno Victor , Gonçalves-Ribeiro Samuel , Salazar Ramon , Villanueva Alberto , Molleví David G.
Published: April 2023

XLSX file - 879KB, TCGA analysis.
Supplemental Figures 1-5 from Increased Expression of System xc− in Glioblastoma Confers an Altered Metabolic State and Temozolomide Resistance
Authors: Polewski Monika D. , Reveron-Thornton Rosyli F. , Cherryholmes Gregory A. , Marinov Georgi K. , Cassady Kaniel , Aboody Karen S.
Published: April 2023

Supplementary Figure 1. Pharmacologic inhibition with SSZ inhibits proliferation of U251 glioma cells in a dose-dependent manner while increasing apoptosis. Supplementary Figure 2. Establishment of stable lentivirus-transduced shSLC7A11 and SLC7A11 U251 glioma cell lines. Supplementary Figure 3. SLC7A11 over-expressing U251 glioma is more resistant to oxidative stress. Supplementary Figure 4. SLC7A11 over-expressing U251 glioma is more resistant to apoptosis induced by TMZ. Supplementary Figure 5. Gene expression changes upon SLC7A11 knock-down in U251 cells.
Supplementary Table 4 from A Monotonic and Prognostic Genomic Signature from Fibroblasts for Colorectal Cancer Initiation, Progression, and Metastasis
Authors: Berdiel-Acer Mireia , Cuadras Daniel , Díaz-Maroto Natalia Guillén , Sanjuan Xavier , Serrano Teresa , Berenguer Antoni , Moreno Victor , Gonçalves-Ribeiro Samuel , Salazar Ramon , Villanueva Alberto , Molleví David G.
Published: April 2023

PDF file - 39KB, PAM analysis (19-gene classifier). Genes are ordered in terms of contribution to the correct classification of a given sample as a recurrent or non-recurrent.
Supplemental Figure Legends from A Novel EGFR Extracellular Domain Mutant, EGFRΔ768, Possesses Distinct Biological and Biochemical Properties in Neuroblastoma
Authors: Keller James , Nimnual Anjaruwee S. , Varghese Mathew S. , VanHeyst Kristen A. , Hayman Michael J. , Chan Edward L.
Published: April 2023

Supplemental Figure Legends 1-7
Supplementary Table 1 from A Monotonic and Prognostic Genomic Signature from Fibroblasts for Colorectal Cancer Initiation, Progression, and Metastasis
Authors: Berdiel-Acer Mireia , Cuadras Daniel , Díaz-Maroto Natalia Guillén , Sanjuan Xavier , Serrano Teresa , Berenguer Antoni , Moreno Victor , Gonçalves-Ribeiro Samuel , Salazar Ramon , Villanueva Alberto , Molleví David G.
Published: April 2023

PDF file - 19KB, fibroblast, tumor stage, gender, age.
STR profiles of the neuroblastoma cell lines from A Novel EGFR Extracellular Domain Mutant, EGFRΔ768, Possesses Distinct Biological and Biochemical Properties in Neuroblastoma
Authors: Keller James , Nimnual Anjaruwee S. , Varghese Mathew S. , VanHeyst Kristen A. , Hayman Michael J. , Chan Edward L.
Published: April 2023

S3. STR profiles of BE(2)C, BE(2)-M17 and IMR32.
Expression level of the EGFRÎ"768 and WT-EGFR in the stable 3T3 clones from A Novel EGFR Extracellular Domain Mutant, EGFRΔ768, Possesses Distinct Biological and Biochemical Properties in Neuroblastoma
Authors: Keller James , Nimnual Anjaruwee S. , Varghese Mathew S. , VanHeyst Kristen A. , Hayman Michael J. , Chan Edward L.
Published: April 2023

S6. These clones were used for the XTT assay.
Erlotinib treatment effect on EGFRÎ"768+ and control GFP+ 3T3 clones from A Novel EGFR Extracellular Domain Mutant, EGFRΔ768, Possesses Distinct Biological and Biochemical Properties in Neuroblastoma
Authors: Keller James , Nimnual Anjaruwee S. , Varghese Mathew S. , VanHeyst Kristen A. , Hayman Michael J. , Chan Edward L.
Published: April 2023

S4. n = 6 for EGFRÎ"768 and n = 8 for GFP cells.
Supplemental Figure 1 from Patient Mutation Directed shRNA Screen Uncovers Novel Bladder Tumor Growth Suppressors
Authors: Hensel Jonathan , Duex Jason E. , Owens Charles , Dancik Garrett M. , Edwards Michael G. , Frierson Henry F. , Theodorescu Dan
Published: April 2023

Supplemental Figure 1. Knockdown of IQGAP1 has no effect on ERK1/2 activity when cells were grown in monolayer culture.
Data Supplement from Targeted Deletion and Lipidomic Analysis Identify Epithelial Cell COX-2 as a Major Driver of Chemically Induced Skin Cancer
Authors: Jiao Jing , Ishikawa Tomo-O , Dumlao Darren S. , Norris Paul C. , Magyar Clara E. , Mikulec Carol , Catapang Art , Dennis Edward A. , Fischer Susan M. , Herschman Harvey R.
Published: April 2023

COX-2 immunostaining of samples collected from (A) untreated skin, (B) one-time TPA treated skin (24 hrs after treatment), and from (C) skin and (D) a papilloma from same mouse after the DMBA/TPA skin tumor induction protocol (24 hrs after 20 week treatment) from Cox-2fl/fl mice. Scale bar: 100µm.
Figure S4 from Distinct Effects of Adipose-Derived Stem Cells and Adipocytes on Normal and Cancer Cell Hierarchy
Authors: Anjanappa Manjushree , Burnett Riesa , Zieger Michael A. , Merfeld-Clauss Stephanie , Wooden William , March Keith , Tholpady Sunil , Nakshatri Harikrishna
Published: April 2023

The effect of HGF and IFNgamma on MCF10A cells
Supplemental Figures 1-10 from Deubiquitinase USP18 Loss Mislocalizes and Destabilizes KRAS in Lung Cancer
Authors: Mustachio Lisa Maria , Lu Yun , Tafe Laura J. , Memoli Vincent , Rodriguez-Canales Jaime , Mino Barbara , Villalobos Pamela Andrea , Wistuba Ignacio , Katayama Hiroyuki , Hanash Samir M. , Roszik Jason , Kawakami Masanori , Cho Kwang-jin , Hancock John F. , Chinyengetere Fadzai , Hu Shanhu , Liu Xi , Freemantle Sarah J. , Dmitrovsky Ethan
Published: April 2023

S1. Introduction of enzymatically-active USP18 overcomes growth inhibition of USP18-repressed lung cancer cells. S2. Loss of USP18 expression reduces growth of KRAS mutant human lung cancer cells. S3. Interferon (IFN) treatment of lung cancer cells having repressed USP18 expression promotes growth inhibition. S4. Modifying USP18 expression alters KRAS protein levels. S5. USP18 regulates KRAS post-transcriptionally. S6. Repression of USP18 expression downregulates AKT and MAPK signaling pathways. S7. KRAS is ISG15-modified. S8. USP18 knockdown promotes KRAS localization to the endomembrane compartment. S9. KrasLA2/+ mice were crossed with Usp18-/- mice to generate KrasLA2/+/Usp18-/- compound mice. S10. KRAS mRNA is increased with presence of activating KRAS mutations and USP18 protein expression is augmented in the presence of high KRAS levels.
Supplemental Figure S1 from Defining ATM-Independent Functions of the Mre11 Complex with a Novel Mouse Model
Authors: Balestrini Alessia , Nicolas Laura , Yang-lott Katherine , Guryanova Olga A. , Levine Ross L. , Bassing Craig H. , Chaudhuri Jayanta , Petrini John H.J.
Published: April 2023

Nbs1deltaB/deltaB Atm -/- immortalized MEFs show inability to form colonies at atmospheric oxygen levels.
Supplementary Figure 1 from Actin-Binding Protein, Espin: A Novel Metastatic Regulator for Melanoma
Authors: Yanagishita Takeshi , Yajima Ichiro , Kumasaka Mayuko , Kawamoto Yoshiyuki , Tsuzuki Toyonori , Matsumoto Yoshinari , Watanabe Daisuke , Kato Masashi
Published: April 2023

PDF file - 44K, Gene maps of Espin isoforms.
Supplementary Figure 5 from Autotaxin and LPA1 and LPA5 Receptors Exert Disparate Functions in Tumor Cells versus the Host Tissue Microenvironment in Melanoma Invasion and Metastasis
Authors: Lee Sue-Chin , Fujiwara Yuko , Liu Jianxiong , Yue Junming , Shimizu Yoshibumi , Norman Derek D. , Wang Yaohong , Tsukahara Ryoko , Szabo Erzsebet , Patil Renukadevi , Banerjee Souvik , Miller Duane D. , Balazs Louisa , Ghosh Manik C. , Waters Christopher M. , Oravecz Tamas , Tigyi Gabor J.
Published: April 2023

Supplementary Figure 5. ATX and LPA receptor profiling in isolated rat alveolar type I-like (A) or type II (B) epithelial cells. Note that expression levels in type II alveolar cells are approximately 10-fold lower than in type I-like cells. Data presented are representative of an experiment performed three times in quadruplicates and are expressed as mean {plus minus} SD.
Data Supplement from Bioactive Lipids, LPC and LPA, Are Novel Prometastatic Factors and Their Tissue Levels Increase in Response to Radio/Chemotherapy
Authors: Schneider Gabriela , Sellers Zachariah Payne , Abdel-Latif Ahmed , Morris Andrew J. , Ratajczak Mariusz Z.
Published: April 2023

Supplementary Figure 3. Ki16425 is not toxic against RMS cells. Panel A - Proliferation of RH30 cells pretreated for 1h with 10 μM or 50 μM Ki15425 in comparison to control cells pretreated with vehicle only. Panel B - Representative FACS analysis of Anexin V binding and propidium iodide incorporation into RMS cells 24h after pre-treatment with Ki16425. Panel C - Analysis of Anexin V and propidium iodide staining in cells 24h and 48h after 1h pre-treatment pre with Ki16425. Pre-treatment was done in PBS, then cells were washed out from inhibitor, resuspended in medium supplemented with 10% FBS and cultured in suspension in low cell adherence dishes. Panel D - Analysis of Anexin V and propidium iodide staining in RMS cells exposed for 48 hours to Ki16425. Cells were incubated in the presence of inhibitor in medium supplemented with 0.5% BSA or 10% FBS.
Supplementary Figure 4 from Autotaxin and LPA1 and LPA5 Receptors Exert Disparate Functions in Tumor Cells versus the Host Tissue Microenvironment in Melanoma Invasion and Metastasis
Authors: Lee Sue-Chin , Fujiwara Yuko , Liu Jianxiong , Yue Junming , Shimizu Yoshibumi , Norman Derek D. , Wang Yaohong , Tsukahara Ryoko , Szabo Erzsebet , Patil Renukadevi , Banerjee Souvik , Miller Duane D. , Balazs Louisa , Ghosh Manik C. , Waters Christopher M. , Oravecz Tamas , Tigyi Gabor J.
Published: April 2023

Supplementary Figure 4. Effect of BMP22 on the basal invasion of B16F10 cells across a matrigel layer. Data are representative of an experiment performed twice in quadruplicates and are expressed as mean {plus minus} SD. *Denotes p value < 0.05 using one-way ANOVA followed by a Bonferroni post-test.
Dataset S2 from Stromal Senescence By Prolonged CDK4/6 Inhibition Potentiates Tumor Growth
Authors: Guan Xiangnan , LaPak Kyle M. , Hennessey Rebecca C. , Yu Christina Y. , Shakya Reena , Zhang Jianying , Burd Christin E.
Published: April 2023

Real-time PCR hit validation.
Figure S2 from p120-Catenin Downregulation and PIK3CA Mutations Cooperate to Induce Invasion through MMP1 in HNSCC
Authors: Kidacki Michal , Lehman Heather L. , Green Michelle V. , Warrick Joshua I. , Stairs Douglas B.
Published: April 2023

Representative images of Boyden-chamber matrigel invasion assay in NOK cells. Scale bars = 50μm. n=3.
Data Supplement from Cyclosporin A Promotes Tumor Angiogenesis in a Calcineurin-Independent Manner by Increasing Mitochondrial Reactive Oxygen Species
Authors: Zhou Alice Yao , Ryeom Sandra
Published: April 2023

Supplementary Data Figure Legends
Supplementary Figure 6 from Mcl-1 Mediates TWEAK/Fn14-Induced Non–Small Cell Lung Cancer Survival and Therapeutic Response
Authors: Whitsett Timothy G. , Mathews Ian T. , Cardone Michael H. , Lena Ryan J. , Pierceall William E. , Bittner Michael , Sima Chao , LoBello Janine , Weiss Glen J. , Tran Nhan L.
Published: April 2023

PDF file - 101K, EU-5148 inhibits Mcl-1-Bim protein interaction.
Supplemental Table 1 from USP6 Confers Sensitivity to IFN-Mediated Apoptosis through Modulation of TRAIL Signaling in Ewing Sarcoma
Authors: Henrich Ian C. , Young Robert , Quick Laura , Oliveira Andre M. , Chou Margaret M.
Published: April 2023

GSEA analysis
Supplemental Figure 6 from USP6 Confers Sensitivity to IFN-Mediated Apoptosis through Modulation of TRAIL Signaling in Ewing Sarcoma
Authors: Henrich Ian C. , Young Robert , Quick Laura , Oliveira Andre M. , Chou Margaret M.
Published: April 2023

RTqPCR of FasL and death receptors
Supplemental Figure 5 from USP6 Confers Sensitivity to IFN-Mediated Apoptosis through Modulation of TRAIL Signaling in Ewing Sarcoma
Authors: Henrich Ian C. , Young Robert , Quick Laura , Oliveira Andre M. , Chou Margaret M.
Published: April 2023

Apoptotic pathways overview and controls for CRISPR and inhibitors
Supplementary Figures S1 - S2 from Differential Response of Glioma Stem Cells to Arsenic Trioxide Therapy Is Regulated by MNK1 and mRNA Translation
Authors: Bell Jonathan B. , Eckerdt Frank , Dhruv Harshil D. , Finlay Darren , Peng Sen , Kim Seungchan , Kroczynska Barbara , Beauchamp Elspeth M. , Alley Kristen , Clymer Jessica , Goldman Stewart , Cheng Shi-Yuan , James C. David , Nakano Ichiro , Horbinski Craig , Mazar Andrew P. , Vuori Kristiina , Kumthekar Priya , Raizer Jeffrey , Berens Michael E. , Platanias Leonidas C.
Published: April 2023

These figures show the PN and MES specific drugs identified by the follow-up cell viability screen. Also shown are the enrichment of translation gene sets in MES GSCs. Relates to Figure 1.
Supplementary Methods and Figure S1 from Downregulation of Critical Oncogenes by the Selective SK2 Inhibitor ABC294640 Hinders Prostate Cancer Progression
Authors: Schrecengost Randy S. , Keller Staci N. , Schiewer Matthew J. , Knudsen Karen E. , Smith Charles D.
Published: April 2023

Contains Figure S1; SK2 siRNA validates Myc depletion by ABC294640. Supplemental methods for figure S1 also included.
Table S3 from Chemoradiotherapy Resistance in Colorectal Cancer Cells is Mediated by Wnt/β-catenin Signaling
Authors: Emons Georg , Spitzner Melanie , Reineke Sebastian , Möller Janneke , Auslander Noam , Kramer Frank , Hu Yue , Beissbarth Tim , Wolff Hendrik A. , Rave-Fränk Margret , Heßmann Elisabeth , Gaedcke Jochen , Ghadimi B. Michael , Johnsen Steven A. , Ried Thomas , Grade Marian
Published: April 2023

siRNAs sequences.
Table S1 from Chemoradiotherapy Resistance in Colorectal Cancer Cells is Mediated by Wnt/β-catenin Signaling
Authors: Emons Georg , Spitzner Melanie , Reineke Sebastian , Möller Janneke , Auslander Noam , Kramer Frank , Hu Yue , Beissbarth Tim , Wolff Hendrik A. , Rave-Fränk Margret , Heßmann Elisabeth , Gaedcke Jochen , Ghadimi B. Michael , Johnsen Steven A. , Ried Thomas , Grade Marian
Published: April 2023

Experimental conditions for cellular viability assays and dual luciferase reporter assays.
Supplementary Table S4 from Integrated Genetic, Epigenetic, and Transcriptional Profiling Identifies Molecular Pathways in the Development of Laterally Spreading Tumors
Authors: Hesson Luke B. , Ng Benedict , Zarzour Peter , Srivastava Sameer , Kwok Chau-To , Packham Deborah , Nunez Andrea C. , Beck Dominik , Ryan Regina , Dower Ashraf , Ford Caroline E. , Pimanda John E. , Sloane Mathew A. , Hawkins Nicholas J. , Bourke Michael J. , Wong Jason W.H. , Ward Robyn L.
Published: April 2023

Epigenetically inactivated, upregulated, downregulated and differentially expressed genes.
Supplementary Table S3 from Integrated Genetic, Epigenetic, and Transcriptional Profiling Identifies Molecular Pathways in the Development of Laterally Spreading Tumors
Authors: Hesson Luke B. , Ng Benedict , Zarzour Peter , Srivastava Sameer , Kwok Chau-To , Packham Deborah , Nunez Andrea C. , Beck Dominik , Ryan Regina , Dower Ashraf , Ford Caroline E. , Pimanda John E. , Sloane Mathew A. , Hawkins Nicholas J. , Bourke Michael J. , Wong Jason W.H. , Ward Robyn L.
Published: April 2023

Somatic mutations identified by WES.
Supplementary Figure Legends from mTOR Inhibition Potentiates HSP90 Inhibitor Activity via Cessation of HSP Synthesis
Authors: Acquaviva Jaime , He Suqin , Sang Jim , Smith Donald L. , Sequeira Manuel , Zhang Chaohua , Bates Richard C. , Proia David A.
Published: April 2023

PDF file - 47K
Supplementary Figure 1 from mTOR Inhibition Potentiates HSP90 Inhibitor Activity via Cessation of HSP Synthesis
Authors: Acquaviva Jaime , He Suqin , Sang Jim , Smith Donald L. , Sequeira Manuel , Zhang Chaohua , Bates Richard C. , Proia David A.
Published: April 2023

PDF file - 355K, Chemical structures of ganetespib and PI3K/mTOR inhibitor compounds used in the study.
Data Supplement from Glucose-6–phosphatase Is a Key Metabolic Regulator of Glioblastoma Invasion
Authors: Abbadi Sara , Rodarte Julio J. , Abutaleb Ameer , Lavell Emily , Smith Chris L. , Ruff William , Schiller Jennifer , Olivi Alessandro , Levchenko Andre , Guerrero-Cazares Hugo , Quinones-Hinojosa Alfredo
Published: April 2023

Supplementary Figure S1, related to Experimental Procedures: Molecular characterization of primary BTICs. Supplementary Figure S2, related to Supplementary Figure 1: BTICs recover their proliferative and invasive capacities in vitro. Supplementary Figure S3, related to Supplementary Figure 3: BTICs express G6PC and its inhibition decreases cell migration, invasion and proliferation. Supplementary Figure S4, related to Supplementary Figure 3: G6PC knockdowns exhibit decreased cell invasion and migration. Supplementary Figure S5, related to Supplementary Figure 4: Pharmacological inhibition of G6PC induces an increase in the expression of the astrocytic marker GFAP in the recovery group. Supplementary Figure S6, related to Supplementary Figure 5: G6PC knockdown activates glycogen synthase (GYS1) and inhibits glycogen phosphorylase (PYGL). Supplementary Figure S7, related to Supplementary Figure 6: Invasion and proliferation capacity of BTICs in vivo.
Supplementary Table from Exploiting AR-Regulated Drug Transport to Induce Sensitivity to the Survivin Inhibitor YM155
Authors: Nyquist Michael D. , Corella Alexandra , Burns John , Coleman Ilsa , Gao Shuai , Tharakan Robin , Riggan Luke , Cai Changmeng , Corey Eva , Nelson Peter S. , Mostaghel Elahe A.
Published: April 2023

Correlation of tumor androgen levels with SLC35F2 transcript expression in PDX models
Data Supplement from Cytoskeletal Regulatory Gene Expression and Migratory Properties of B-cell Progenitors Are Affected by the ETV6–RUNX1 Rearrangement
Authors: Palmi Chiara , Fazio Grazia , Savino Angela M. , Procter Julia , Howell Louise , Cazzaniga Valeria , Vieri Margherita , Longinotti Giulia , Brunati Ilaria , Andrè Valentina , Della Mina Pamela , Villa Antonello , Greaves Mel , Biondi Andrea , D'Amico Giovanna , Ford Anthony , Cazzaniga Giovanni
Published: April 2023

Supplementary Figures 1-6. Supplementary Figure 1: RQ-PCR analyses of adhesion molecule expression in control and ETV6-RUNX1 positive Ba/F3 cells. Supplementary Figure 2: Phenotypic analyses of control and ETV6-RUNX1 positive Ba/F3 cells. Supplementary Figure 3: Analysis of the role of CCL2/CCR2 axis in the CXCL12 migratory defects of ETV6-RUNX1 positive Ba/F3 cells. Supplementary Figure 4: Analysis of the role of CXCR7, FLT3L receptor and CDC42 in the CXCL12 migratory defects of ETV6-RUNX1 positive Ba/F3 cells. Supplementary Figure 5: Phenotypic analyses of Pre-BI MIGR-GFP and MIGRETV6-RUNX1 cells. Supplementary Figure 6: Migration assay of PreBI cells towards CXCL12 in presence or not of EGF.
Supplementary Table from Loss of Keratinocytic RXRα Combined with Activated CDK4 or Oncogenic NRAS Generates UVB-Induced Melanomas via Loss of p53 and PTEN in the Tumor Microenvironment
Authors: Coleman Daniel J. , Chagani Sharmeen , Hyter Stephen , Sherman Anna M. , Löhr Christiane V. , Liang Xiaobo , Ganguli-Indra Gitali , Indra Arup K.
Published: April 2023

Antibodies used for experiments. Supplementary Table S2: PCR primers used for genotyping of mouse lines.
Supplementary Data from Pathology-Driven Comprehensive Proteomic Profiling of the Prostate Cancer Tumor Microenvironment
Authors: Staunton Lisa , Tonry Claire , Lis Rosina , Espina Virginia , Liotta Lance , Inzitari Rosanna , Bowden Michaela , Fabre Aurelie , O'Leary John , Finn Stephen P. , Loda Massimo , Pennington Stephen R.
Published: April 2023

Additional method details, tables and figures to support text in the manuscript. Figure S.1 Protein yield from LCM of regions of interest. Figure S.2 Variations on data analysis in the Perseus software. Figure S.3 Incidence of Biochemical Recurrence in Sample Cohort for Immunohistochemistry. Figure S.4 Expression of significant proteins in 'normal' patient biopsy tissue. Table S1.1 Significantly changing proteins between G3 epithelia and stroma. Table S1.2 Significantly changing proteins between G4 epithelia and stroma. Table S.1.3 Significantly changing proteins between G3 and G4 epithelia Table S1.4 Significantly changing proteins between G3 and G4 Stroma
Supplementary Figure Legends from P-Cadherin Promotes Ovarian Cancer Dissemination Through Tumor Cell Aggregation and Tumor–Peritoneum Interactions
Authors: Usui Akihiro , Ko Song Yi , Barengo Nicolas , Naora Honami
Published: April 2023

PDF file - 70K
Supplementary Figure 4 from Active FOXO1 Is a Key Determinant of Isoform-Specific Progesterone Receptor Transactivation and Senescence Programming
Authors: Diep Caroline H. , Knutson Todd P. , Lange Carol A.
Published: April 2023

FOXO1 enhances progestin-dependent PR-A transcriptional activity in Hela cells.
Supplementary Figure S4 from FOXO3a and Posttranslational Modifications Mediate Glucocorticoid Sensitivity in B-ALL
Authors: Consolaro Francesca , Ghaem-Maghami Sadaf , Bortolozzi Roberta , Zona Stefania , Khongkow Mattaka , Basso Giuseppe , Viola Giampietro , Lam Eric W.-F.
Published: April 2023

The resistant REH cells were treated with LY294002 (30μM), PI-103 (30μM) or Rapamycin (30μM) in the absence or presence of dexamethasone (1μM). Cell viability analysis was performed after 48 h using MTT assay. (t-test 2-tailed: treated verses untreated cells) *significant p<0.05, ** very significant p<0.01 and ns: not significant.
Supplementary Figure 4 from The Nuclear Pool of Tetraspanin CD9 Contributes to Mitotic Processes in Human Breast Carcinoma
Authors: Rappa Germana , Green Toni M. , Lorico Aurelio
Published: April 2023

Abrogation of CD9 expression in MDA-CD9sh cells.
Supplemental Figures and Tables from Oncogenic STRAP Supports Hepatocellular Carcinoma Growth by Enhancing Wnt/β-Catenin Signaling
Authors: Wang Wenhui , Li Shan , Liu Pengyu , Sideras Kostandinos , van de Werken Harmen J.G. , van der Heide Marieke , Cao Wanlu , Lavrijsen Marla , Peppelenbosch Maikel P. , Bruno Marco , Pan Qiuwei , Smits Ron
Published: April 2023

S1. Specificity of STRAP antibody tested on a STRAP knock-out Huh6 clone and control thereof. S2. Knockout of the STRAP gene by CRISPR/Cas9 technology in HCC cell lines. S3. Elevated expression of STRAP in DEN-induced mouse liver tumors (T) compared with flanking normal liver tissue (N). S4. Analysis of the TCGA liver cancer cohort reveals that no significant difference in average STRAP RNA levels is observed between normal and tumor samples. S5. Baseline levels of STRAP protein and RNA in a panel of 9 HCC cell lines. S6. Log2 fold change of liver stemness markers (A), liver differentiation related genes (B) and TGF-β signaling target genes (C) in STRAP knock-out clones compared to controls. Supplemental Table S1. Gene mutations of Wnt/β-catenin signaling components in HCC cell lines. Supplemental Table S2. Clinicopathologic characteristics of HCC TMA. Supplemental Table S3. Selected STRAP sgRNAs. Supplemental Table S4. Primer sequences of STRAP used for Sanger sequencing. Supplemental Table S5. Primer sequence used for Ion Torrent sequencing. Supplemental Table S6. Primer sequences used for qRT-PCR Supplemental Table S7. Gene information
supplementary Data from Therapeutic Effect of Quinacrine, an Antiprotozoan Drug, by Selective Suppression of p-CHK1/2 in p53-Negative Malignant Cancers
Authors: Park Soyoung , Oh Ah-Young , Cho Jung-Hyun , Yoon Min-Ho , Woo Tae-Gyun , Kang So-mi , Lee Ho-Young , Jung Youn-Jin , Park Bum-Joon
Published: April 2023

supplementary Figure S1-10
Supplemental Fig. 5 from Nuclear Receptor CAR Suppresses GADD45B-p38 MAPK Signaling to Promote Phenobarbital-induced Proliferation in Mouse Liver
Authors: Hori Takeshi , Saito Kosuke , Moore Rick , Flake Gordon P. , Negishi Masahiko
Published: April 2023

Expression of the GADD45 (A, B, and G) and Cyp2b10 genes following PB treatment.
Supplementary File 1 from Histone H3.3K27M Mobilizes Multiple Cancer/Testis (CT) Antigens in Pediatric Glioma
Authors: Deng Houliang , Zeng Jianming , Zhang Ting , Gong Longcai , Zhang Hongjie , Cheung Edwin , Jones Chris , Li Gang
Published: April 2023

The sequence analysis of different variants of VCX3A and VCX3B.
Figure S2 from STAT3 Targets ERR-α to Promote Epithelial–Mesenchymal Transition, Migration, and Invasion in Triple-Negative Breast Cancer Cells
Authors: Ma Jia-Hui , Qi Jie , Lin Shi-Qi , Zhang Cai-Yun , Liu Fang-yuan , Xie Wei-Dong , Li Xia
Published: April 2023

The illustration of STAT3/ERR-α signaling pathway.
Supplementary Materials and Methods from Centrosome Linker–induced Tetraploid Segregation Errors Link Rhabdoid Phenotypes and Lethal Colorectal Cancers
Authors: Remo Andrea , Manfrin Erminia , Parcesepe Pietro , Ferrarini Alberto , Han Hye Seung , Mickys Ugnius , Laudanna Carmelo , Simbolo Michele , Malanga Donatella , Oliveira Duarte Mendes , Baritono Elisabetta , Colangelo Tommaso , Sabatino Lina , Giuliani Jacopo , Molinari Enrico , Garonzi Marianna , Xumerle Luciano , Delledonne Massimo , Giordano Guido , Ghimenton Claudio , Lonardo Fortunato , D'angelo Fulvio , Grillo Federica , Mastracci Luca , Viglietto Giuseppe , Ceccarelli Michele , Colantuoni Vittorio , Scarpa Aldo , Pancione Massimo
Published: April 2023

The file contains supplementary Materials and Methods
Supplementary Figures 1-9 from Centrosome Linker–induced Tetraploid Segregation Errors Link Rhabdoid Phenotypes and Lethal Colorectal Cancers
Authors: Remo Andrea , Manfrin Erminia , Parcesepe Pietro , Ferrarini Alberto , Han Hye Seung , Mickys Ugnius , Laudanna Carmelo , Simbolo Michele , Malanga Donatella , Oliveira Duarte Mendes , Baritono Elisabetta , Colangelo Tommaso , Sabatino Lina , Giuliani Jacopo , Molinari Enrico , Garonzi Marianna , Xumerle Luciano , Delledonne Massimo , Giordano Guido , Ghimenton Claudio , Lonardo Fortunato , D'angelo Fulvio , Grillo Federica , Mastracci Luca , Viglietto Giuseppe , Ceccarelli Michele , Colantuoni Vittorio , Scarpa Aldo , Pancione Massimo
Published: April 2023

S1. Whole exome sequencing analysis of two rhabdoid colorectal cancers (RC). S2. Non-silent somatic mutations in rhabdoid tumours are enriched in centrosome-microtubule components. S3. Effect of CROCC mutations on centrosome phenotype. S4. CROCC expression profiling in classical colorectal cancers (CRCs). S5. Allelic loss at the 1p36.13 locus correlates with chromosomal instability in colorectal cancer cells. S6. Centrosome and chromosome instability in colorectal cancer cells. S7. Mitotic errors and impaired cell cycle caused by stable CROCC depletion in RKO cells. S8. Invasive behavior of colorectal cancer cells triggered by CROCC depletion. S9. Mitotic aberrations suppressed by CROCC or microtubule stabilizing agents in metastatic T84 and HT29 colorectal cancer cells.
Figure S1 from Targeting IDH1 as a Prosenescent Therapy in High-grade Serous Ovarian Cancer
Authors: Dahl Erika S. , Buj Raquel , Leon Kelly E. , Newell Jordan M. , Imamura Yuka , Bitler Benjamin G. , Snyder Nathaniel W. , Aird Katherine M.
Published: April 2023

Ovcar3 and Ovcar10 cells are wildtype for IDH1; RT-qPCR primers and shRNA binding sites.
Supplementary Table 4 from ELF4 Is a Target of miR-124 and Promotes Neuroblastoma Proliferation and Undifferentiated State
Authors: Kosti Adam , Du Liqin , Shivram Haridha , Qiao Mei , Burns Suzanne , Garcia Juan Gabriel , Pertsemlidis Alexander , Iyer Vishwanath R. , Kokovay Erzsebet , Penalva Luiz O.F.
Published: April 2023

Table S4. PANTHER and mSigDB analysis of siELF4 down- and up-regulated genes.
Figure S2 from β4-Integrin/PI3K Signaling Promotes Tumor Progression through the Galectin-3–N-Glycan Complex
Authors: Kariya Yukiko , Oyama Midori , Hashimoto Yasuhiro , Gu Jianguo , Kariya Yoshinobu
Published: April 2023

Analysis of MDA-MB435S cells expressing control lacZ, WT, and â^†N.
Supplementary Table 2 from ELF4 Is a Target of miR-124 and Promotes Neuroblastoma Proliferation and Undifferentiated State
Authors: Kosti Adam , Du Liqin , Shivram Haridha , Qiao Mei , Burns Suzanne , Garcia Juan Gabriel , Pertsemlidis Alexander , Iyer Vishwanath R. , Kokovay Erzsebet , Penalva Luiz O.F.
Published: April 2023

Table S2. siELF4 differentially expressed genes.
Supplementary Figure Legends from ELF4 Is a Target of miR-124 and Promotes Neuroblastoma Proliferation and Undifferentiated State
Authors: Kosti Adam , Du Liqin , Shivram Haridha , Qiao Mei , Burns Suzanne , Garcia Juan Gabriel , Pertsemlidis Alexander , Iyer Vishwanath R. , Kokovay Erzsebet , Penalva Luiz O.F.
Published: April 2023

Figure S1. Knockdown efficiency 48 h after reverse transfection. Figure S2. miR-124 directly binds ELF4 and regulates ELF4 expression. Figure S3. ELF4 ectopic expression antagonizes the effect of miR-124 on differentiation of KELLY cells. Figure S4. ELF4 ectopic expression antagonizes the effect of miR-124 on differentiation of SK-N-DZ cells. Figure S5. High ELF4 expression correlates with poor prognosis of neuroblastoma patients. Figure S6. Synergistic effect of ALK and ELF4 inhibition on differentiation and proliferation of KELLY cells. Figure S7. Validation of RNA-seq Results.
Supplementary Movie 5 from O-GlcNAcylation Enhances Double-Strand Break Repair, Promotes Cancer Cell Proliferation, and Prevents Therapy-Induced Senescence in Irradiated Tumors
Authors: Efimova Elena V. , Appelbe Oliver K. , Ricco Natalia , Lee Steve S.-Y. , Liu Yue , Wolfgeher Donald J. , Collins Tamica N. , Flor Amy C. , Ramamurthy Aishwarya , Warrington Sara , Bindokas Vytautas P. , Kron Stephen J.
Published: April 2023

Time-lapse live cell imaging of caspase-3/7 activation in irradiated Panc02 cells treated with PUGNAc or alloxan
Supplementary Figure S1 from Runx2 Suppression by miR-342 and miR-363 Inhibits Multiple Myeloma Progression
Authors: Gowda Pramod S. , Wildman Benjamin J. , Trotter Timothy N. , Xu Xiaoxuan , Hao Xiaoxiao , Hassan Mohammad Q. , Yang Yang
Published: April 2023

Assess expression levels of DKK1 and RANKL.
Supplementary Data (included supplementary methods, figures and tables) from Enhanced Activity of Variant DNA Polymerase β (D160G) Contributes to Cisplatin Therapy by Impeding the Efficiency of NER
Authors: Wang Meina , Li Enjie , Lin Lin , Kumar Alagamuthu Karthick , Pan Feiyan , He Lingfeng , Zhang Jing , Hu Zhigang , Guo Zhigang
Published: April 2023

Supplementary Table 1: DNA substrates for pol β activity and BER assays Supplementary Table 2: Salt bridges of WT and D160G pol β protein Supplementary Table 3: Primers for D160G mutant and sequence for XPA knock down Supplementary Figure 1. SDS-PAGE of the WT and D160G pol β. Proteins were purified by Ni-NTA column from E. coli. Supplementary Figure 2. ELISA tested the same amount of WT and D160G pol β protein were precoated on microtiter plates in DNA-binding assay. Supplementary Figure 3. Western blot analysis of polβ protein levels in 786-0 cells. Similar protein levels of D160G and wild-type pol β were used in BER assays. Supplementary Figure 4. Real-time PCR analysis of polβ mRNA levels in 786-0 cell (A) and MCF-7 cell (B). Data represent the mean {plus minus}SD. Student's t-test. Supplementary Figure 5. Cell transformation assay. Supplementary figure 6. Overexpression of WT or D160G pol β caused no significant apoptosis(A) and γH2AX foci (B) in cells. Supplementary Figure 7. Western blot analysis of XPA protein levels. XPA was knock-down by shRNA in MCF-7 cells expressing vector, WT or D160G pol β.
Supplementary Table 2 from LINC00152 Promotes Invasion through a 3′-Hairpin Structure and Associates with Prognosis in Glioblastoma
Authors: Reon Brian J. , Takao Real Karia Bruno , Kiran Manjari , Dutta Anindya
Published: April 2023

List of oligonucleotides used in this study.
Supplemental Tables 1-5, Supplemental Figure 1-2 from Breast Cancer Risk–Associated SNPs in the mTOR Promoter Form De Novo KLF5- and ZEB1-Binding Sites that Influence the Cellular Response to Paclitaxel
Authors: Chen Qiuchen , Deng Xiaolan , Hu Xiaoyun , Guan Shu , He Miao , Wang Yilin , Wei Binbin , Zhang Jing , Zhao Haishan , Yao Weifan , Jin Feng , Liu Yong , Chen Jianjun , Olapade Olufunmilayo I. , Wu Huizhe , Wei Minjie
Published: April 2023

Table S1. Frequencies of mTOR promoter polymorphisms in patients with breast cancer and healthy controls Table S2. Frequency distribution of mTOR haplotypes and their associations with the risk of developing breast cancer Table S3. Association of mTOR haplotypes with clinicopathological parameters in patients with breast cancer Table S4. Association of mTOR polymorphisms with clinicopathological parameters in patients with breast cancer Table S5. Association of mTOR polymorphisms with therapeutic response to neoadjuvant chemotherapy (n=131) Figure S1. The impact of forced expression of pcmTOR-Ht1 or pcmTOR-Ht2 on cell proliferation and cell cycle and chemoresistance to PTX in MCF7/PTX cells. Figure S2. Plasma concentration of PTX detection by using UPLC-MS/MS method.
Supplementary Figure 2 from LINC00152 Promotes Invasion through a 3′-Hairpin Structure and Associates with Prognosis in Glioblastoma
Authors: Reon Brian J. , Takao Real Karia Bruno , Kiran Manjari , Dutta Anindya
Published: April 2023

LINC00152 does not affect U87 cell proliferation rate. A) qRT-PCR showing knockdown of LINC00152 after treatment with two different siRNAs. B) Cell proliferation rate measured by MTT assay of U87 cells treated with two different siRNA against LINC00152. C) qRT-PCR showing overexpression of LINC00152 after LINC00152 full length overexpression. D) Cell proliferation rates of U87 cells with and without LINC00152 overexpression.
Supplementary Data from SREBF1 Activity Is Regulated by an AR/mTOR Nuclear Axis in Prostate Cancer
Authors: Audet-Walsh Étienne , Vernier Mathieu , Yee Tracey , Laflamme Chloé , Li Susan , Chen Yonghong , Giguère Vincent
Published: April 2023

S1. ChIP-qPCR of SREBF1 in LNCaP cells after treatment with R1881, with infection of shRNA control (NTC; non-targeted control) or against SREBF1 (shSRE_1 and shSRE_2). S2. Protein expression of unprocessed SREBF1, with and without siRNAmediated knockdown (siSREBF1) in 22rv1 PCa cells. Tubulin is shown as a loading control. Phosphorylation status of S6, a downstream target of mTOR, is shown as a control of mTOR activation by R1881 (n=2). Supplemental Table 1. Human qRT-PCR primers. Supplemental Table 2. Human ChIP-qPCR primers.
Supplementary Figure 7 from SPHK1 Is a Novel Target of Metformin in Ovarian Cancer
Authors: Hart Peter C. , Chiyoda Tatsuyuki , Liu Xiaojing , Weigert Melanie , Curtis Marion , Chiang Chun-Yi , Loth Rachel , Lastra Ricardo , McGregor Stephanie M. , Locasale Jason W. , Lengyel Ernst , Romero Iris L.
Published: April 2023

SPHK1 expression does not alter other markers of metformin sensitivity.
Supplementary Figure 4 from SPHK1 Is a Novel Target of Metformin in Ovarian Cancer
Authors: Hart Peter C. , Chiyoda Tatsuyuki , Liu Xiaojing , Weigert Melanie , Curtis Marion , Chiang Chun-Yi , Loth Rachel , Lastra Ricardo , McGregor Stephanie M. , Locasale Jason W. , Lengyel Ernst , Romero Iris L.
Published: April 2023

Metformin inhibits induction of SPHK1 transcription by HIFs.
Supplementary Figure S4 from Expression Profiling of Circulating Microvesicles Reveals Intercellular Transmission of Oncogenic Pathways
Authors: Milani Gloria , Lana Tobia , Bresolin Silvia , Aveic Sanja , Pastò Anna , Frasson Chiara , te Kronnie Geertruy
Published: April 2023

(A) cMYC expression in leukemic cell lines. (B) cMYC transcript levels in MVs released from parental cell lines.
Supplementary Figure S3 from Expression Profiling of Circulating Microvesicles Reveals Intercellular Transmission of Oncogenic Pathways
Authors: Milani Gloria , Lana Tobia , Bresolin Silvia , Aveic Sanja , Pastò Anna , Frasson Chiara , te Kronnie Geertruy
Published: April 2023

(A) MEIS1 and HOXA9 expression in leukemic cell lines. (B) MVs uptake of two MLL-hallmarks transcripts, over-expressed downstream the MLL fusion protein in both RS(4;11) cells, who carry the MLL-AF4 translocation, and in SHI-1 cells, carrying the MLL-AF6 rearrangement.
Supplementary Figure S2 from Expression Profiling of Circulating Microvesicles Reveals Intercellular Transmission of Oncogenic Pathways
Authors: Milani Gloria , Lana Tobia , Bresolin Silvia , Aveic Sanja , Pastò Anna , Frasson Chiara , te Kronnie Geertruy
Published: April 2023

cABL (p120) protein studied in K562 cells and K562 MVs.
Supplementary Methods from Interactions with Muscle Cells Boost Fusion, Stemness, and Drug Resistance of Prostate Cancer Cells
Authors: Uygur Berna , Leikina Evgenia , Melikov Kamran , Villasmil Rafael , Verma Santosh K. , Vary Calvin P.H. , Chernomordik Leonid V.
Published: April 2023

Supplementary Methods
Table S1 from Antisecretory Factor–Mediated Inhibition of Cell Volume Dynamics Produces Antitumor Activity in Glioblastoma
Authors: Ilkhanizadeh Shirin , Sabelström Hanna , Miroshnikova Yekaterina A. , Frantz Aaron , Zhu Wen , Idilli Aurora , Lakins Jon N. , Schmidt Christin , Quigley David A. , Fenster Trenten , Yuan Edith , Trzeciak Jacqueline R. , Saxena Supna , Lindberg Olle R. , Mouw Janna K. , Burdick Jason A. , Magnitsky Sergey , Berger Mitchel S. , Phillips Joanna J. , Arosio Daniele , Sun Dandan , Weaver Valerie M. , Weiss William A. , Persson Anders I.
Published: April 2023

Compression-induced changes in the transcriptional GBM phenotype. Differentially expressed genes in tumorspheres derived from human GBMs (GBM5, GBM14, GBM34, and GBM43) when comparing compression to other conditions.
Figure S7 from Antisecretory Factor–Mediated Inhibition of Cell Volume Dynamics Produces Antitumor Activity in Glioblastoma
Authors: Ilkhanizadeh Shirin , Sabelström Hanna , Miroshnikova Yekaterina A. , Frantz Aaron , Zhu Wen , Idilli Aurora , Lakins Jon N. , Schmidt Christin , Quigley David A. , Fenster Trenten , Yuan Edith , Trzeciak Jacqueline R. , Saxena Supna , Lindberg Olle R. , Mouw Janna K. , Burdick Jason A. , Magnitsky Sergey , Berger Mitchel S. , Phillips Joanna J. , Arosio Daniele , Sun Dandan , Weaver Valerie M. , Weiss William A. , Persson Anders I.
Published: April 2023

Fig. S7. AF reversed compression-induced transcriptional phenotype of GBM tumorspheres. Both (A-B) smaller and (C-D) larger GBM43 tumorspheres expanded in response to 48h compression. (***P < 0.05, Student's t-test). (E) Principle components analysis of all expressed genes. The first principle component is associated with GBM subtype, while the second principle component is associated with the presence of compression. (F) Heat map of genes differentially expressed when comparing compression to other conditions (see supplementary table S1 for gene list).
Supplementary Figure and Table Legendslegends from Imprecision and DNA Break Repair Biased towards Incompatible End Joining in Leukemia
Authors: Gassner Franz Josef , Schubert Maria , Rebhandl Stefan , Spandl Karina , Zaborsky Nadja , Catakovic Kemal , Blaimer Stephanie , Hebenstreit Daniel , Greil Richard , Geisberger Roland
Published: April 2023

Supplementary Figure and Table Legendslegends from Imprecision and DNA Break Repair Biased towards Incompatible End Joining in Leukemia
Supplementary Figure S1 from Imprecision and DNA Break Repair Biased towards Incompatible End Joining in Leukemia
Authors: Gassner Franz Josef , Schubert Maria , Rebhandl Stefan , Spandl Karina , Zaborsky Nadja , Catakovic Kemal , Blaimer Stephanie , Hebenstreit Daniel , Greil Richard , Geisberger Roland
Published: April 2023

Sequences of the 9 DNA substrates used for the DNA repair assay. Restriction sites for linearization are indicated. Primer binding sites are colored red, unique 6bp motifs used for substrate identification of resected junctions are colored green.
Supplementary Figure S2 from Association of USP10 with G3BP2 Inhibits p53 Signaling and Contributes to Poor Outcome in Prostate Cancer
Authors: Takayama Ken-ichi , Suzuki Takashi , Fujimura Tetsuya , Takahashi Satoru , Inoue Satoshi
Published: April 2023

Supplementary Figure S2. USP10 regulates androgen-dependent signals and G3BP2 protein level in VCaP cells.
Supplementary Figure S4 from Functional Toll-like Receptor 4 Overexpression in Papillary Thyroid Cancer by MAPK/ERK–Induced ETS1 Transcriptional Activity
Authors: Peyret Victoria , Nazar Magalí , Martín Mariano , Quintar Amado A. , Fernandez Elmer A. , Geysels Romina C. , Fuziwara Cesar S. , Montesinos María M. , Maldonado Cristina A. , Santisteban Pilar , Kimura Edna T. , Pellizas Claudia G. , Nicola Juan P. , Masini-Repiso Ana M.
Published: April 2023

Conditional HRasG12V and RET/PTC3 expression upregulate TLR4 expression at the plasma membrane.
Supplemental Figure Legends from Competitive Kinase Enrichment Proteomics Reveals that Abemaciclib Inhibits GSK3β and Activates WNT Signaling
Authors: Cousins Emily M. , Goldfarb Dennis , Yan Feng , Roques Jose , Darr David , Johnson Gary L. , Major Michael B.
Published: April 2023

Supplemental Figure Legends
Supplemental Figures 1-7 and Supplemental Table 1 from Cholesterol Sulfotransferase SULT2B1b Modulates Sensitivity to Death Receptor Ligand TNFα in Castration-Resistant Prostate Cancer
Authors: Vickman Renee E. , Yang Jiang , Lanman Nadia A. , Cresswell Gregory M. , Zheng Faye , Zhang Chi , Doerge R. W. , Crist Scott A. , Mesecar Andrew D. , Hu Chang-Deng , Ratliff Timothy L.
Published: April 2023

Figure S1 provides quality control from scRNA-seq analysis. Figure S2 indicates altered pathways in SULT2B1b KD cells. Figure S3 demonstrates TNF and SULT2B1b KD interact to further reduce AR activity in LNCaP cells. Figure S4 demonstrates that TNFR expression is not altered by SULT2B1b KD. Figure S5 demonstrates that SULT2B1b KD induces TRADD expression in LNCaP cells. Figure S6 indicates SULT2B1 is expressed at low levels. Figure S7 supports that TRAIL, TL1, and DAXX are not involved in apoptosis in SULT2B1b KD cells. Table S1 gives correlations of SULT2B1 with TNF-related genes.
Supplementary Materials and Methods, Figures S1 - S4 from Inhibition of CD95/CD95L (FAS/FASLG) Signaling with APG101 Prevents Invasion and Enhances Radiation Therapy for Glioblastoma
Authors: Blaes Jonas , Thomé Carina M. , Pfenning Philipp-Niclas , Rübmann Petra , Sahm Felix , Wick Antje , Bunse Theresa , Schmenger Torsten , Sykora Jaromir , von Deimling Andreas , Wiestler Benedikt , Merz Christian , Jugold Manfred , Haberkorn Uwe , Abdollahi Amir , Debus Jürgen , Gieffers Christian , Kunz Claudia , Bendszus Martin , Kluge Michael , Platten Michael , Fricke Harald , Wick Wolfgang , Lemke Dieter
Published: April 2023

Supplementary Figure 1: Detection of asunercept/ APG101 in brains of treated mice. Supplementary Figure 2: qPCR for MMP2 (A) or MMP9 (B) and representative images of human microglia after 12 h treatment with vehicle (I), 20 µg/ml APG101 (II), 50 U/ml CD95L (III) and both 20 µg/ml APG101 and 50 U/ml CD95L (IV). Supplementary Figure 3: APG101 is effective in murine cells. Supplementary Figure 4: Radiation effects on CD95L expression.
Supplementary Figure S2 from Cortactin Phosphorylation by Casein Kinase 2 Regulates Actin-Related Protein 2/3 Complex Activity, Invadopodia Function, and Tumor Cell Invasion
Authors: Markwell Steven M. , Ammer Amanda G. , Interval Erik T. , Allen Jessica L. , Papenberg Brenen W. , Hames River A. , Castaño Johnathan E. , Schafer Dorothy A. , Weed Scott A.
Published: April 2023

ECM degradation analysis of OSC19 and UMSCC1 cells with cortactin knockdown.
Supplementary Material from Novel Intergenically Spliced Chimera, NFATC3-PLA2G15, Is Associated with Aggressive T-ALL Biology and Outcome
Authors: Bond Jonathan , Tran Quang Christine , Hypolite Guillaume , Belhocine Mohamed , Bergon Aurélie , Cordonnier Gaëlle , Ghysdael Jacques , Macintyre Elizabeth , Boissel Nicolas , Spicuglia Salvatore , Asnafi Vahid
Published: April 2023

Supplementary Methods, Tables, figures and references.
Supplementary Figure Legends from Cortactin Phosphorylation by Casein Kinase 2 Regulates Actin-Related Protein 2/3 Complex Activity, Invadopodia Function, and Tumor Cell Invasion
Authors: Markwell Steven M. , Ammer Amanda G. , Interval Erik T. , Allen Jessica L. , Papenberg Brenen W. , Hames River A. , Castaño Johnathan E. , Schafer Dorothy A. , Weed Scott A.
Published: April 2023

Supplementary Figure Legends from Cortactin Phosphorylation by Casein Kinase 2 Regulates Actin-Related Protein 2/3 Complex Activity, Invadopodia Function, and Tumor Cell Invasion
Figure S7 from AP-1 Signaling by Fra-1 Directly Regulates HMGA1 Oncogene Transcription in Triple-Negative Breast Cancers
Authors: Tolza Claire , Bejjani Fabienne , Evanno Emilie , Mahfoud Samantha , Moquet-Torcy Gabriel , Gostan Thierry , Maqbool Muhammad Ahmad , Kirsh Olivier , Piechaczyk Marc , Jariel-Encontre Isabelle
Published: April 2023

Effect of Fra-1 down-regulation on Pol II P-Ser5 and Pol II P-Ser2
Table S1 from High Prevalence of a Hotspot of Noncoding Somatic Mutations in Intron 6 of GPR126 in Bladder Cancer
Authors: Garinet Simon , Pignot Géraldine , Vacher Sophie , Le Goux Constance , Schnitzler Anne , Chemlali Walid , Sirab Nanor , Barry Delongchamps Nicolas , Zerbib Marc , Sibony Mathilde , Allory Yves , Damotte Diane , Bieche Ivan
Published: April 2023

Relationship between GPR126 mutation status and standard clinical pathological and biological parameters in bladder cancer