bluuebunny/crossref_metadata_2025 huggingface dataset:
Decoding the Gaugino Code Naturally at High-Lumi LHC
Authors: Baer Howard , Barger Vernon , Zhang Kairui
Published: October 2024

Natural supersymmetry with light higgsinos is most favored to emerge from the string landscape, since the volume of a scan parameter space shrinks to tiny volumes for electroweak unnatural models. Rather general arguments favor a landscape selection of soft SUSY breaking terms tilted to large values, but they are tempered by the atomic principle that the derived value of the weak scale in each pocket universe lies not too far from its measured value in our universe. But, that leaves (at least) three different paradigms for gaugino masses in natural SUSY models: unified (as in nonuniversal Higgs models), anomaly mediation form (as in natural AMSB), and mirage mediation form (with comparable moduli- and anomaly-mediated contributions). We perform landscape scans for each of these, and we show that they populate different, but overlapping, positions in m(ℓℓ¯) and m(wino) space. The first of these may be directly measurable at high-lumi LHC via the soft opposite-sign dilepton plus jets plus E/T signature arising from higgsino pair production, while the second of these could be extracted from direct wino pair production, leading to same-sign diboson production.
Pathophysiology and Prevention of Manual-Ventilation-Induced Lung Injury (MVILI)
Authors: White Luke A. , Conrad Steven A. , Alexander Jonathan Steven
Published: October 2024

Manual ventilation, most commonly with a bag-valve mask, is a form of short-term ventilation used during resuscitative efforts in emergent and out-of-hospital scenarios. However, compared to mechanical ventilation, manual ventilation is an operator-dependent skill that is less well controlled and is highly subject to providing inappropriate ventilation to the patient. This article first reviews recent manual ventilation guidelines set forth by the American Heart Association and European Resuscitation Council for providing appropriate manual ventilation parameters (e.g., tidal volume and respiratory rate) in different patient populations in the setting of cardiopulmonary resuscitation. There is then a brief review of clinical and manikin-based studies that demonstrate healthcare providers routinely hyperventilate patients during manual ventilation, particularly in emergent scenarios. A discussion of the possible mechanisms of injury that can occur during inappropriate manual hyperventilation follows, including adverse hemodynamic alterations and lung injury such as acute barotrauma, gastric regurgitation and aspiration, and the possibility of a subacute, inflammatory-driven lung injury. Together, these injurious processes are described as manual-ventilation-induced lung injury (MVILI). This review concludes with a discussion that highlights recent progress in techniques and technologies for minimizing manual hyperventilation and MVILI, with a particular emphasis on tidal-volume feedback devices.
Trends in Marijuana Use among Adolescents in the United States
Authors: Yang Jack , Mejia Maria C. , Sacca Lea , Hennekens Charles H. , Kitsantas Panagiota
Published: October 2024

Background: Marijuana is a widely used substance in the United States (US) and worldwide. We explored trends in self-reported marijuana use among US adolescents overall as well as by gender, race/ethnicity, and school grade. Methods: Biennial data from the Youth Risk Behavior Survey from 2011 to 2021 included 88,183 adolescents in grades 9th through 12th. We used percentage change as a measure of effect and the chi-square test for significance. All analyses were conducted at the national level. Results: The percentage of adolescents who reported current marijuana use dropped significantly from 23.1% in 2011 to 15.8% in 2021 (p < 0.05). The self-report of trying marijuana for the first time before age 13 also decreased significantly from 8.1% in 2011 to 4.9% in 2021 (p < 0.05). For current use, there were similar significant decreases by race/ethnicity, with Asian, Hispanic, and White adolescents experiencing the steepest declines. In 2021, the percentage of Black adolescents self-reporting marijuana use was significantly higher (20.5%) compared to White (14.8%), Hispanic (16.7%), and Asian (5.1%) adolescents. Although current marijuana use declined significantly for both girls and boys over time, in 2021 girls were more likely (17.8%) to currently use marijuana than boys (13.6%). In 2011, the opposite was true, with boys (25.9%) being more likely to use marijuana than girls (20.1%). Conclusions: In US adolescents in 2021, there were decreases in self-reports of marijuana use compared to 2011. Behavioral interventions within school and family environments may be critical in mitigating the risk of marijuana use.
Respiratory Syncytial Virus in Pregnancy: An Obstetrics View
Authors: Dominoni Mattia , Gardella Barbara , Spinillo Arsenio
Published: October 2024

Respiratory syncytial virus (RSV) represents one of the most prevalent causes of lower respiratory tract infection in newborns and children by the time they are two years old, with a peak rate of hospitalization in those between two and three months of age and a high risk of morbidity and mortality, especially under the age of six months of life [...]
Probiotic and Postbiotic Potentials of Enterococcus faecalis EF-2001: A Safety Assessment
Authors: Han Kwon Il , Shin Hyun-Dong , Lee Yura , Baek Sunhwa , Moon Eunjung , Park Youn Bum , Cho Junhui , Lee Jin-Ho , Kim Tack-Joong , Manoharan Ranjith Kumar
Published: October 2024

Background: Probiotics, which are live microorganisms that, when given in sufficient quantities, promote the host’s health, have drawn a lot of interest for their ability to enhance gut health. Enterococcus faecalis, a member of the human gut microbiota, has shown promise as a probiotic candidate due to its functional attributes. However, safety concerns associated with certain strains warrant comprehensive evaluation before therapeutic application. Materials and Methods: In this study, E. faecalis EF-2001, originally isolated from fecal samples of a healthy human infant, was subjected to a multi-faceted assessment for its safety and probiotic potential. In silico analysis, CAZyme, biosynthetic, and stress-responsive proteins were identified. Results: The genome lacked biogenic amine genes but contained some essential amino acid and vitamin synthetic genes, and carbohydrate-related enzymes essential for probiotic properties. The negligible difference of 0.03% between the 1st and 25th generations indicates that the genetic information of the E. faecalis EF-2001 genome remained stable. The live E. faecalis EF-2001 (E. faecalis EF-2001L) demonstrated low or no virulence potential, minimal D-Lactate production, and susceptibility to most antibiotics except some aminoglycosides. No bile salt deconjugation or biogenic amine production was observed in an in vitro assay. Hemolytic activity assessment showed a β-hemolytic pattern, indicating no red blood cell lysis. Furthermore, the EF-2001L did not produce gelatinase and tolerated simulated gastric and intestinal fluids in an in vitro study. Similarly, heat-killed E. faecalis EF-2001 (E. faecalis EF-2001HK) exhibits tolerance in both acid and base conditions in vitro. Further, no cytotoxicity of postbiotic EF-2001HK was observed in human colorectal adenocarcinoma HT-29 cells. Conclusions: These potential properties suggest that probiotic and postbiotic E. faecalis EF-2001 could be considered safe and retain metabolic activity suitable for human consumption.
Club Drugs and Psychiatric Outcomes: A Descriptive Case Series from Spain
Authors: Montemitro Chiara , Mosca Alessio , Chiappini Stefania , Miuli Andrea , Schifano Fabrizio , Montano Maria Josè Gordillo , Villar Cristina Merino del , Allegretti Rita , Marrangone Carlotta , Di Petta Gilberto , De Berardis Domenico , Pettorruso Mauro , Martinotti Giovanni
Published: October 2024

Background: illegal drugs significantly contribute to global health issues, with health complications often occurring not only in regular users with Substance Use Disorders (SUDs) but also in first-time and occasional users. Methods: this study examines five clinical cases from a public hospital in Ibiza, Spain, where patients presented with acute psychiatric symptoms due to recreational drug use. Results: Contrary to previous studies on SUDs, our patients typically had higher education levels and stable employment. Most of them used multiple substances, with cannabis, cocaine, and alcohol being the most frequently used. There was also a common occurrence of consuming drugs with uncertain contents. Upon admission, typical symptoms included aggression, hallucinations, mood swings, and disorientation in time and space. Conclusions: Our findings underscore the significant mental health risks posed by illicit drugs, even for individuals with no prior psychiatric history. Factors like the drug’s potency, frequency and amount of use, past mental health issues, personality traits, and previous traumatic experiences might influence the onset of these symptoms.
Synthesis and Bioevaluation of New Stable Derivatives of Chrysin-8-C-Glucoside That Modulate the Antioxidant Keap1/Nrf2/HO-1 Pathway in Human Macrophages
Authors: Ávila-Román Javier , Quevedo-Tinoco Lirenny , Oliveros-Ortiz Antonio J. , García-Gil Sara , Rodríguez-García Gabriela , Motilva Virginia , Gómez-Hurtado Mario A. , Talero Elena
Published: October 2024

Background/Objectives: The beneficial effects of the flavonoid chrysin can be reduced by its poor oral bioavailability. It has been shown that chrysin-8-C-glucoside (1) has a better absorption capability. The aim of this study was to evaluate the antioxidant and anti-inflammatory activity of this glucoside, as well as the respective hexa-acetate derivative 1a and the hexa-ethyl carbonate derivative 1b since the inclusion of moieties in bioactive molecules may increase or modify their biological effects. Methods: THP-1 macrophages were used to determine the viability in the presence of chrysin derivatives, and non-cytotoxic concentrations were selected. Subsequently, lipopolysaccharide (LPS)-induced reactive oxygen species (ROS) production and inflammatory mediators were examined. The involvement of chrysin derivatives with the Keap1 and Nrf2 antioxidant system was determined by docking and Western blotting studies. Results: Our data demonstrated, for the first time, that pretreatment with the three compounds caused a significant reduction in LPS-induced reactive oxygen species (ROS) production and pro-inflammatory cytokines tumor necrosis factor alpha (TNF-α) and interleukin 1β (IL-1β) levels, as well as in cyclooxygenase 2 (COX-2) expression. The mechanisms underlying these protective effects were related, at least in part, to the competitive molecular interactions of these phenolic compounds with Kelch-like ECH-associated protein 1 (Keap1)–nuclear factor erythroid 2-related factor 2 (Nrf2), which would allow the dissociation of Nrf2 and its translocation into the nucleus and the subsequent up-regulation of hemo-oxygenase 1 (HO-1) expression. Conclusions: Compared to the 8-C-glucoside parent chrysin, compound 1a exhibited the strongest antioxidant and anti-inflammatory activity. We hypothesized that the incorporation of an acetate group (1a) may reduce its polarity and, thus, increase membrane permeability, leading to better pharmacological activity. These findings support the potential use of these phenolic compounds as Nrf2 activators against oxidative-stress-related inflammatory diseases.
Astronomical Intensity Interferometry
Authors: Yi Shufei , An Qichang , Zhang Wenyi , Hu Jincai , Wang Liang
Published: October 2024

The development of astronomy relies heavily on advances in high-resolution imaging techniques. With the growing demand for high-resolution astronomical observations, conventional optical interferometry has gradually revealed various limitations, especially in coping with atmospheric phase fluctuations and long baseline observations. However, intensity interferometry is becoming an important method to overcome these challenges due to its high robustness to atmospheric phase fluctuations and its excellent performance in long-baseline observations. In this paper, the basic principles and key technologies of intensity interferometry are systematically described, and the remarkable potential of this technique for improving angular resolution and detection sensitivity is comprehensively discussed in light of the recent advances in modern photon detector and signal processing techniques. The results show that the intensity interferometry technique is capable of realizing high-precision observation of long-range and low-brightness targets, especially in the field of exoplanet detection, which shows a wide range of application prospects. In the future, with the continuous development of telescope arrays and adaptive optics, the intensity interferometry technique is expected to further promote the precision and breadth of astronomical observations, and provide new opportunities for revealing the mysteries of the universe.
Nonlinear Optical Microscopic Imaging for Real-Time Gaseous Chemical Sensing
Authors: Ariunbold Gombojav O. , Semon Bryan , Carlson Logan , Bandi Thejesh N.
Published: October 2024

Nonlinear optical microscopic imaging techniques have advanced for chemically sensitive imaging of solid and liquid samples but lack advancements for gaseous samples. In this work, wide-field three-color ultrafast coherent anti-Stokes Raman scattering microscopy is implemented for selectively imaging the ambient nitrogen gas. Our technique operates by capturing a series of spectrally selected images with a rate of 5–10 frames per second. The recorded data are analyzed both qualitatively and quantitatively. This technique has been demonstrated to be sensitive to a variation of approximately 1011 nitrogen molecules in ambient air confined within a microscopic volume of 10 μm by 50 μm by 50 μm. We believe that our approach can potentially be extended toward real-time, in situ chemical imaging of the microscopic dynamics of gases, for example, in ammonia for nitrogen cycle, greenhouse gases for environmental pollution, plant fertilization regulation for precision agriculture, or byproducts produced from lower-temperature plasmas.
Non-Pharmacological Therapies for Management of Temporomandibular Myofascial Pain Syndrome: Laser Photobiomodulation or Dry Needling? Meta-Analyses of Human Clinical Trials
Authors: Alsarhan Jumana , El Feghali Rita , Alkhudari Thaer , Benedicenti Stefano
Published: October 2024

This review aims to compare the effect of photobiomodulation therapy (PBMT) using visible and near-infrared diode laser wavelengths to that of the dry needling technique (DNT) on the management of orofacial pain in patients with Temporomandibular Disorder Myofascial Pain Syndrome (TMD/MPS) in term of effectiveness, speed of recovery, and lasting of treatment. A systematic search of multiple electronic databases was carried out to identify the relevant clinical trials published between 1 January 2010 and 1 January 2024. The included studies were limited to human subjects who had orofacial pain associated with Axis 1 of TMD/MPS, involving two genders with age >18 years and were treated either with photobiomodulation using diode laser with wavelengths ranging from 600 up to 1200 nanometer (nm), or with the dry needling (DN) technique (superficial SDN or deep DDN), as a non-pharmacological therapies to decrease the intensity of orofacial pain associated with TMD/MPS. The risk of bias for included studies was assessed using the Cochrane RoB tool (for randomized studies). Three distinct meta-analyses were performed to quantify the pooled effects of PBM and DN in the management of TMD/MPS myofascial pain and deactivation of myofascial trigger points (MTPs). The meta-analyses were performed using Review Manager (RevMan) 5.3 from Cochrane. The confidence interval (CI) was established at 95% and p-values of less than 0.05 (p < 0.05) were considered statistically significant. Statistical heterogeneity was assessed using I2. Qualitative data were extracted and summarized in tables for each group study, while quantitative data were reported as Mean and Standard Deviation (SD) values for assessment variables in each sub-group study. The results among groups were systematically evaluated to draw the final conclusion. A rigorous electronic and manual search revealed 4150 possible articles. Following the application of the inclusion and exclusion criteria, twelve eligible studies were included in the analysis. Both PBMT and DNT were found to be effective in controlling the myalgia pain and primary symptoms associated with TMD/MPS, as well as deactivating the MTPs. DNT was statistically superior in terms of recovery time while PBMT was the more effective long-term therapy.
Camouflage Breaking with Stereo-Vision-Assisted Imaging
Authors: Yao Han , Chen Libang , Lin Jinyan , Liu Yikun , Zhou Jianying
Published: October 2024

Camouflage is a natural or artificial process that prevents an object from being detected, while camouflage breaking is a countering process for the identification of the concealed object. We report that a perfectly camouflaged object can be retrieved from the background and detected with stereo-vision-assisted three-dimensional (3D) imaging. The analysis is based on a binocular neuron energy model applied to general 3D settings. We show that a perfectly concealed object with background interference can be retrieved with vision stereoacuity to resolve the hidden structures. The theoretical analysis is further tested and demonstrated with distant natural images taken by a drone camera, processed with a computer and displayed using autostereoscopy. The recovered imaging is presented with the removal of background interference to demonstrate the general applicability for camouflage breaking with stereo imaging and sensing.
Advancements and Prospects in Algal Biofuel Production: A Comprehensive Review
Authors: Falfushynska Halina
Published: October 2024

Microalgae represent a valuable renewable resource for biofuel production due to their high lipid content, rapid growth rates, and non-competition with food resources. Both freshwater species like Chlorella and marine species such as Dunaliella, Tetraselmis, and Nannochloropsis are among the most commonly utilized candidates. This review provides a comprehensive overview of current cultivation and harvesting methodologies for microalgae in the context of biofuel production, emphasizing sustainable aviation fuel and biohydrogen. It synthesizes recent findings, technological advancements, and practical implementations to enhance the productive and economic viability of microalgae-based biofuels, highlighting their potential as a sustainable renewable energy source. Among the biofuels, sustainable aviation fuel and biohydrogen stand out as significant contributors to reducing greenhouse gas emissions. Technologies such as the oil-to-jet process and Fischer–Tropsch synthesis are being optimized to convert algal lipids into high-quality fuels. Biohydrogen offers several advantages, including the potential for negative CO2 emissions and compatibility with existing hydrogen infrastructure. Despite the challenges associated with the high costs of cultivation and processing, advances in biotechnological methods and process engineering promise to overcome these barriers. This review highlights the importance of continued research and development to maximize the potential of microalgal biofuels in achieving sustainable energy goals and contributing to global efforts in mitigating climate change.
Green Silver Nanoparticles: Plant-Extract-Mediated Synthesis, Optical and Electrochemical Properties
Authors: Stozhko Natalia , Tarasov Aleksey , Tamoshenko Viktoria , Bukharinova Maria , Khamzina Ekaterina , Kolotygina Veronika
Published: October 2024

Antioxidants of plant extract play an important role in the phytosynthesis of silver nanoparticles (phyto-AgNPs), providing the reduction of silver ions and capping and stabilization of nanoparticles. Despite the current progress in the studies of phytosynthesis, there is no approach to the selection of plant extract for obtaining phyto-AgNPs with desired properties. This work shows that antioxidant activity (AOA) of plant extracts is a key parameter for targeted phytosynthesis. In support of this fact, the synthesis of phyto-AgNPs was carried out using extracts of four plants with different AOA, increasing in the order Ribes uva-crispa < Lonicera caerulea < Fragaria vesca < Hippophae rhamnoides. Phyto-AgNPs have been characterized using Fourier-transform infrared spectroscopy, transmission electron microscopy, energy-dispersive X-ray spectroscopy, selected area electron diffraction technique, ultraviolet–visible spectroscopy, electrochemical impedance spectroscopy and cyclic voltammetry. It was established that the change in the AOA of the plant extract is accompanied by a size-dependent change in the optical and electrochemical properties of phyto-AgNPs. In particular, an increase in the extract AOA leads to the formation of smaller phyto-AgNPs with higher electrochemical activity and low charge transfer resistance. A “blue shift” and an increase in the plasmon resonance band of silver sols are observed with an increase in the extract AOA. The obtained regularities prove the existence of the “AOA–size–properties” triad, which can be used for controlled phytosynthesis and prediction of phyto-AgNPs’ properties.
Adaptive Seedling Strategies in Seasonally Dry Tropical Forests: A Comparative Study of Six Tree Species
Authors: Espinosa Carlos Ivan , Esparza Elvia , Jara-Guerrero Andrea
Published: October 2024

This study examines seed germination strategies and seedling establishment in six tree species typical of seasonally dry tropical forests. We focused on how interspecific and intraspecific differences in seed size and germination speed influence biomass allocation and seedling growth. Using generalized linear models, we analyzed the effects of these traits on root/shoot ratios and growth rates. Our findings reveal two main strategies: slow germination, high root/shoot ratio, and low growth rate in Erythrina velutina Willd and Terminalia valverdeae A.H. Gentry, associated with enhanced drought tolerance. In contrast, Cynophalla mollis (Kunth) J. Presl and Coccoloba ruiziana Lindau exhibited rapid germination, lower root/shoot ratios, and low to moderate growth rates, favoring competition during early establishment. Centrolobium ochroxylum Rose ex Rudd partially aligned with this second strategy due to its fast growth. Vachellia macracantha (Humb. & Bonpl. ex Willd.) Seigler & Ebinger presented a unique case, displaying slow germination and a broad range in both root/shoot ratios and growth rates. At the intraspecific level, significant variation in biomass allocation and growth rate was observed, influenced by germination speed and seed weight. We discuss the adaptive significance of seed traits in SDTFs and their role in seedling establishment under varying environmental conditions, providing insights for strategies for conservation and restoration in these ecosystems.
Differences in the Virulence Between Local Populations of Puccinia striiformis f. sp. tritici in Southwest China
Authors: Yang Fang , Wang Yunjing , Ji Zhiying , Liu Jiahui , Zhang Mei , Peng Yunliang , Zhao Jie , Ji Hongli
Published: October 2024

The virulence analysis of Puccinia stiiformis f. sp. tritici (Pst), the cause of wheat stripe rust, is essential for predicting and managing the disease epidemic in Southwest China, where the wheat cultivation has significantly reduced in the past few decades due to the impact of this disease. From 2020 to 2021, 196 Pst isolates were collected from Guizhou, Yunnan, and Sichuan. The virulence and race assessments were conducted using Chinese differential genotypes. Additionally, the resistance expression of 102 wheat lines was evaluated in 2021 in two disease nurseries located in Ningnan and Jiangyou. All the 45 Pst isolates from Guizhou and Yunnan belonged to pathogroup Hybrid 46, with 36 identified as race CYR32. Among the 69 isolates from the Liangshan Prefecture, 67 belonged to the Hybrid 46 group, while the remaining two were identified as race CYR34 in the G-22 group. Furthermore, all 79 isolates from the western Sichuan Basin belonged to the G-22 group, with 54 identified as race CYR34. The diversity indices of the Pst populations from Guizhou, Sichuan, and Yunnan exhibited a sequential decline. Virulence variation among the Pst populations from Yunnan, Guizhou, and the Ganzi-Liangshan region was minimal; however, significant virulence differences were observed when these populations were compared to those from the western Sichuan Basin. Results from disease nurseries indicated that Pst virulence was notably stronger in Ningnan compared to that in Jiangyou. The Sichuan Basin exhibits a notable diversity in Pst virulence, coupled with a more frequent genetic exchange occurring between the Liangshan Prefecture and the Yunnan-Guizhou Plateau. This information is essential for developing effective management strategies to mitigate the impact of wheat stripe rust in this region.
Transcriptomic Analysis Reveals the Mechanism of Color Formation in the Peel of an Evergreen Pomegranate Cultivar ‘Danruo No.1’ During Fruit Development
Authors: Wang Xiaowen , Yang Chengkun , Zhu Wencan , Weng Zhongrui , Li Feili , Teng Yuanwen , Zhou Kaibing , Qian Minjie , Deng Qin
Published: October 2024

Pomegranate (Punica granatum L.) is an ancient fruit crop that has been cultivated worldwide and is known for its attractive appearance and functional metabolites. Fruit color is an important index of fruit quality, but the color formation pattern in the peel of evergreen pomegranate and the relevant molecular mechanism is still unknown. In this study, the contents of pigments including anthocyanins, carotenoids, and chlorophyll in the peel of ‘Danruo No. 1’ pomegranate fruit during three developmental stages were measured, and RNA-seq was conducted to screen key genes regulating fruit color formation. The results show that pomegranate fruit turned from green to red during development, with a dramatic increase in a* value, indicating redness and anthocyanins concentration, and a decrease of chlorophyll content. Moreover, carotenoids exhibited a decrease–increase accumulation pattern. Through RNA-seq, totals of 30, 18, and 17 structural genes related to anthocyanin biosynthesis, carotenoid biosynthesis and chlorophyll metabolism were identified from differentially expressed genes (DEGs), respectively. Transcription factors (TFs) such as MYB, bHLH, WRKY and AP2/ERF were identified as key candidates regulating pigment metabolism by K-means analysis and weighted gene co-expression network analysis (WGCNA). The results provide an insight into the theory of peel color formation in evergreen pomegranate fruit.
Myrciaria jaboticaba Fruit Peel: Bioactive Composition as Determined by Distinct Harvest Seasons and In Vitro Anti-Cancer Activity
Authors: Nascimento Roberto de Paula do , Rizzato Julia Soto , Polezi Gabriele , Boughanem Hatim , Williams Non Gwenllian , Borguini Renata Galhardo , Santiago Manuela Cristina Pessanha de Araujo , Marostica Junior Mario Roberto , Parry Lee
Published: October 2024

Jaboticaba (Myrciaria jaboticaba) is a recognizable and unique crop from Brazil. The fruit’s byproducts are currently being studied, given their bioactive composition and promising anti-cancer potential. It is not evident, however, if different harvesting seasons can modify the chemical profile and antioxidant capacity of jaboticaba fruit fractions. Furthermore, as there is limited data for jaboticaba’s anti-proliferative effects, additional assessments are required to improve the robustness of these findings. Therefore, this study aimed to determine the composition of the peel of jaboticaba collected in two periods (May—off-season, sample 1—and August–October—peak season, sample 2) and test the peel’s richest anthocyanin sample against colorectal cancer (CRC) cell lines. To accomplish this, proximate, spectrophotometric, and chromatographic analyses were performed in two freeze-dried samples; and anti-proliferative and/or colony-forming assays were carried out in Caco-2, HT29, and HT29-MTX cells. As a result, sample 2 showed the highest levels of polyphenols overall, including flavonoids and anthocyanins. This sample displayed significative higher contents of cyanidin-3-O-glucoside (48%) and delphinidin-3-O-glucoside (105%), in addition to a superior antioxidant capacity (23% higher). Sample 1 showed higher amounts of total protein, gallic acid (20% higher), and specific carotenoids. An aqueous extract from sample 2 was tested against CRC, showing anti-proliferative effects for Caco-2 cells at 1 and 2 mg/mL concentrations, with IC50 values of 1.2–1.3 mg/mL. Additionally, the extract was able to inhibit cell colony formation when tested at both low and high concentrations. In conclusion, jaboticaba collected in the main season stands out regarding its polyphenol composition and holds potential against cancer cell growth.
Identification of New Cultivar and Different Provenances of Dendrocalamus brandisii (Poaceae: Bambusoideae) Using Simple Sequence Repeats Developed from the Whole Genome
Authors: Geng Ruiman , Xu Junlei , Jiang Jutang , Cheng Zhanchao , Sun Maosheng , Xia Nianhe , Gao Jian
Published: October 2024

Dendrocalamus brandisii is a high-quality bamboo species that can be used for both bamboo shoots and wood. The nutritional components and flavors of D. brandisii vary from different geographical provenances. However, the unique biological characteristics of bamboo make morphological classification methods unsuitable for distinguishing them. Although the new cultivar ‘Manxie No.1’ has significant differences in the branch characteristics and the color of shoot sheaths compared to the D. brandisii, it still lacks precise genetic information at the molecular level. This study identified 231,789 microsatellite markers based on the whole genome of D. brandisii and analyzed their type composition and distribution on chromosomes in detail. Then, using TP-M13-SSR fluorescence-labeling technology, 34 pairs of polymorphic primers were screened to identify the new cultivar ‘Manxie No.1’ and 11 different geographical provenances of D. brandisii. We also constructed DNA fingerprinting profiles for them. At the same time, we mapped six polymorphic SSRs to the gene of D. brandisii, among which SSR673 was mapped to DhB10G011540, which is related to plant immunity. The specific markers selected in this study can rapidly identify the provenances and the new cultivar of D. brandisii and help explore candidate genes related to some important traits.
Potential of Ca-Complexed in Amino Acid in Attenuating Salt Stress in Sour Passion Fruit Seedlings
Authors: Souto Antônio Gustavo de Luna , Pessoa Angela Maria dos Santos , Sá Sarah Alencar de , Sousa Nayana Rodrigues de , Barros Emerson Serafim , Morais Francimar Maik da Silva , Ferreira Fagner Nogueira , Silva Wedson Aleff Oliveira da , Batista Rafael Oliveira , Silva Daniel Valadão , Marcelino Rita Magally Oliveira da Silva , Gheyi Hans Raj , Lima Geovani Soares de , Pessoa Rosa Maria dos Santos , Rêgo Mailson Monteiro do
Published: October 2024

Salt stress results in physiological changes that inhibit plant growth and development. Ca-complex sources are used as a potential salt stress attenuator. This study was carried out with the aim of verifying the effects of Ca-complex sources in reducing the effects of saline water stress on the physiological aspects of sour passion fruit seedlings. The experiment was carried out in a randomized block design with a 2 × 2 × 3 factorial scheme, consisting of two cultivars of sour passion fruit (BRS GA1 and BRS SC1), two levels of water salinity (electrical conductivity of 0.5 and 4.0 dS m−1) and three sources of Ca-complex (without, organic acids and amino acids). The traits measured at 60 days after sowing were gas exchange, chlorophyll indices, chlorophyll fluorescence, electrolyte leakage, and relative water content in the leaf limb. Under moderate water salinity, the application of Ca-complex in amino acids promoted increases of 49.84% and 43.71%, respectively, in the efficiency of water use and carboxylation. The application of complex sources increased the stability of cell membranes, reducing electrolyte leakage, providing higher relative water content in seedlings irrigated with moderately saline water. From the results, we conclude that Ca-complex sources have potential as modulators of moderately saline water stress in sour passion fruit seedlings.
Study of Mechanical and Thermal Properties of Environmentally Friendly Composites from Beer Bagasse
Authors: Jordá-Reolid María , Martínez-García Asunción , Ibáñez-García Ana , León-Cabezas Miguel Ángel , Galvañ-Gisbert Josefa
Published: October 2024

The influence of bagasse fibres from beer manufacturing in mechanical, thermal, and rheological properties of three polymers (BioPE, PLA, and PP) has been studied in order to develop new environmentally friendly biocomposites for injection moulding applications. Totals of 10 wt%, 20 wt%, and 30 wt% of bagasse fibre (BSG) were added to the polymers by extrusion compounding, adding specific compatibilising additives, and injected samples were mechanically characterised by tensile, Charpy impact, and hardness tests. In addition, the fractures obtained after the impact test were observed using scanning electron microscopy (SEM) to assess the compatibility matrix filler. Characterisation of the thermal properties is also carried out by using differential scanning calorimetry (DSC) and thermogravimetry (TGA). Additionally, melt flow index of the biocomposites is also studied. An increase in the rigidity of the BioPE and PP composites was produced with the increase in BSG content, dealing with a decrease in maximum strain and impact resistance; whereas, in the filled BGS PLA biocomposites, Young’s modulus was lower than that of the PLA material, improving the ductility of the PLA-BGS formulations. Compatibilisation effect was, therefore, different in the nine developed formulations, and the BGS content also influenced their thermal, mechanical, and rheological behaviours.
Influence of Different Filler Systems on the Thermal Conductivity and Mechanical Properties of Thermosets
Authors: Rösel Uta , Drummer Dietmar
Published: October 2024

The changing demands in terms of the compactness and performance of electronic devices increase the role of thermal management within this application field. Because polymers and especially thermosets have a low thermal conductivity, filler systems have to be used to improve their performance and make thermosets suitable for applications. So far, several factors influencing thermal conductivity have been defined; however, the combined investigation of mechanical properties as another important value in terms of applications has not been realized. Therefore, this paper analyzes thermal conductivity based on the orientation of fillers and a contact path as well as mechanical properties in different material systems. In addition to the matrix material, the filler type and grade and the geometry and size were varied. It was shown that boron nitride provides the best values in terms of thermal conductivity after orientation along the flow path is realized. An aluminum silicate was defined as the best filler system in terms of mechanical properties. However, the boron nitride was found to reveal the greatest potential in terms of applications, since the mechanical properties are likely to be increased by the usage of finishing additives such as silane.
Experimental and Numerical Analysis of Bolted Repair for Composite Laminates with Delamination Damage
Authors: Xiao Shan , Huang Mingxuan , Xu Zhonghai , Yang Yusong , Du Shanyi
Published: October 2024

Composite materials are widely used in aircraft due to the urgent need for high-quality structures in aerospace engineering. In order to verify the effectiveness of complex bolt repairs on composite structures, compression tests have been performed on three types (intact, damaged, and repaired) of composite plate specimens, and finite element simulation results of these three types’ specimens were obtained. The experimental results show that for damaged composite laminates, the strength recovery after bolt repair can reach an impressive 107%, and the delamination propagation caused by over-buckling deformation is considered to be the main cause of failure, which also suggests that although bolt repair can improve the strength of the specimens, it has a limited ability to inhibit delamination propagation. The simulation results of the finite element model in this paper are in good agreement with the actual experimental results, and the maximum error does not exceed 7.9%. In conclusion, this paper verifies the suitability of the proposed repair scheme in engineering applications and the correctness of the modeling method for repaired composite laminates.
Artificial Neural Network Modeling of the Removal of Methylene Blue Dye Using Magnetic Clays: An Environmentally Friendly Approach
Authors: Ates Asude , Demirel Hülya , Altintig Esra , Bozdag Dilay , Usta Yasin , Over Ozçelik Tijen
Published: October 2024

In this study, the effectiveness of Fe3O4-based clay as a cost-effective material for removing methylene blue (MB) dye from aqueous solutions was evaluated. The structural properties of the clay and Fe3O4-based clay were analyzed using SEM, XRF, BET, XRD, FTIR, and TGA techniques. In this research, the effects of various aspects, such as adsorbent amount, contact time, solution pH, adsorption temperature, and initial dye concentration, on the adsorption of Fe3O4-based clay are investigated. The experiments aimed at understanding the adsorption mechanism of Fe3O4-based clay have shown that the adsorption kinetics are accurately described by the pseudo-second order kinetic model, while the equilibrium data are well represented by the Langmuir isotherm model. The maximum adsorption capacity (qm) was calculated as 52.63 mg/g at 25 °C, 53.48 mg/g at 30 °C, and 54.64 mg/g at 35 °C. All variables affecting the MB adsorption process were systematically optimized in a controlled experimental framework. The effectiveness of the artificial neural network (ANN) model was refined by modifying variables such as the quantity of neurons in the latent layer, the number of inputs, and the learning rate. The model’s accuracy was assessed using the mean absolute percentage error (MAPE) for the removal and adsorption percentage output parameters. The coefficient of determination (R2) values for the dyestuff training, validation, and test sets were found to be 99.40%, 92.25%, and 96.30%, respectively. The ANN model demonstrated a mean squared error (MSE) of 0.614565 for the training data. For the validation dataset, the model recorded MSE values of 0.99406 for the training data, 0.92255 for the validation set, and 0.96302 for the test data. In conclusion, the examined Fe3O4-based clays offer potential as effective and cost-efficient adsorbents for purifying water containing MB dye in various industrial settings.
High-Precision Numerical Investigation of a VAWT Starting Process
Authors: Mălăel Ion , Strătilă Sergiu
Published: October 2024

For both conventional and renewable energy conversion processes, computational fluid dynamics (CFD) has been used to address more energy-related challenges in recent decades. Using CFD to investigate vertical-axis wind turbines has become more common in recent years. The main goals of this application have been to more accurately predict the turbine’s performance and to comprehend the complicated nature of the complex turbulent flow. The vertical-axis wind turbine (VAWT) simulation for energy-generating applications has several intricate components. One of them is the study of the chaotic flow that occurs during the first stages of the starting process, and which greatly influences overall effectiveness. In this article, the performance of the wind turbine was increased using a passive flow control approach. The numerical research was carried out using Large Eddy Simulation for four alternative tip speed ratios in both cases, the classic and the optimized case, equipped with a vortex trap on the extrados of the blades. The power and torque coefficient variations, as well as the velocity magnitude contours, show that the starting process may begin with a significant improvement in efficiency when flow control is used.
Synthesis and Characterization of CMC/PAM-Amy Hydrogel and Its Efficacy in Apple Juice Clarification
Authors: Roheen Taleeha , Ramzan Rimsha , Nadeem Muhammad , Atif Farhan Ahmad , Munir Masooma , Qureshi Tahir Mahmood
Published: October 2024

The high amount of starch in fruits is responsible for its post-processing cloudiness. In the current study, α-amylase from porcine pancreases was immobilized onto carboxymethyl cellulose/polyacrylamide (CMC/PAM) hydrogel. This in-house-built CMC/PAM-Amy hydrogel offers a more efficient and sustainable solution for apple juice clarification. To acquire the best immobilization efficiency, the concentration of glutaraldehyde crosslinker was optimized. Biocatalytic characterization studies were brought into consideration for free and immobilized α-amylase. The synthesized native and immobilized CMC/PAM-Amy hydrogels were also characterized using SEM, FTIR and XRD. Under ideal circumstances, the activity of CMC/PAM-Amy was up to 604 μmolmin−1, and its immobilization efficiency was 96.29 ± 1.15%. A kinetic parameters study resulted in a conspicuously lowered Km value for immobilized amylase, signifying its higher affinity for its substrate. CMC/PAM-Amy showed a half-life (t1/2) 3.5 times higher than free-Amy at 50, 55 and 60 °C. The higher values of the inactivation rate constant (kd), free energy of inactivation (ΔG*), enthalpy of inactivation (ΔH*) and change in entropy (ΔS*) of CMC/PAM-Amy manifested the enhanced thermal stability of amylase after immobilization. A reusability study revealed that immobilized amylase retained roughly 70% of its initial catalytic activity after six successive repetitions of the process. CMC/PAM-Amy displayed improved recycling ability operational stability and biocatalytic activity, rendering it an auspicious tool in decreasing the starch content of crude apple juice to about 61% of its total starch content before treatment. Moreover, the values of Brix, viscosity, acidity and turbidity were also decreased in CMC/PAM-Amyclarified apple juice. Therefore, immobilized amylases with other industrial enzymes could be an efficient tool for potential industrial application.
Application, Progress, and Trend of Thickened Acid Fracturing in Carbonate Rock Reservoir Development
Authors: Sui Yu , Cao Guangsheng , Tian Yu , Guo Tianyue , Xiao Zhongmin , Yao Liming
Published: October 2024

The efficient development of carbonate rock reservoirs with rich oil and gas resources has become a hot topic and a focal point in the current oil and gas industry. The development of carbonate rock oil and gas reservoirs differs from that of sandstone reservoirs. Although gas flooding, water flooding, and chemical flooding have been carried out in recent years, the development is still unsatisfactory, and the on-site application of technologies such as nanoparticles is on the rise. For the future development of acid fracturing technology, accurate reservoir geological description, core printing based on additive manufacturing technology, the development of new acid fracturing techniques, and the research and development of acid fracturing equipment will have great research potential and economic value in the development of carbonate rock oil and gas reservoirs. Under the development background of high-temperature deep reservoirs, this paper comprehensively reviews unconventional acidizing fracturing fluids in carbonate rock oil and gas reservoirs. We introduce the main components, corresponding mechanisms of action, current research achievements, and advantages of promising acid fracturing fluids, including thickened acids. We focus on the application and limitations under harsh conditions of high temperature and high salinity while also focusing on the development of thickened acid fracturing technology. The thickening agent is the core of a thickened acid solution. Therefore, this article fully reviews the structure, sources, advantages and disadvantages, as well as the current development status of biological, cellulose, and synthetic polymer thickeners. Synthetic polymers, low-molecular-weight polymers, and small-molecular compound crosslinkers provide clues for temperature and salt-resistant thickeners and also promote the development of tight reservoirs.
A Novel Strength Reduction Method for a Slope Stability Assessment Based on a Finite Element Method
Authors: Gu Yuming , Yuan Yunxing , Xue Kangsheng , Yin Yongming , Lu Sen , Jiang Xutong
Published: October 2024

Ensuring the stability of slopes is critical to the safe operation of geotechnical engineering. Evaluating slope stability to minimize geologic risks induced by destabilization is significant in reducing casualties and property damage. A conventional, single-coefficient strength reduction method is widely applied in slope stability analyses, but this method ignores the attenuation degree of different parameters in the slope destabilization. A new double-strength reduction method considering different contributions of the mechanics’ parameters is proposed in this study for evaluating the stability of nonhomogeneous slope. First, the role of each mechanic’s parameters in the slope destabilization was investigated theoretically and numerically using ABAQUS software 2022. The results indicate that the effect of elasticity (E), Poisson’s ratio (v), and soil gravity (γ) on the evolution of factor of safety (FOS) are insignificant and can be neglected compared with cohesive force (c), and angle of internal friction (φ). Next, an improved method was constructed to correlate the FOS with cohesive force (c) and the angle of internal friction (φ). Then, a numerical method was constructed based on the computation of the mathematical–mechanical relationship between FOS and the mechanical parameters, and the stability of slope is estimation based on the Mohr–Coulomb yield criterion. Finally, the double-strength reduction coefficient method proposed in this study, the limit equilibrium method, and the traditional finite element strength reduction coefficient method were applied to nonhomogeneous slopes and slopes containing a soft underlying layer for comparison, and the difference between them was within the range of ±5%. The results indicate that both the limit equilibrium method and the traditional finite element strength reduction method tend to overestimate the FOS of intricate slopes compared with the evaluated method proposed in this study. This parallel comparison serves to validate the accuracy of the double-strength reduction method proposed in the present study. Further, based on the proposed method, the relationship between slope stability and slope displacement is established, which provides a theoretical basis for the safety assessment of slope engineering.