bluuebunny/crossref_metadata_2025 huggingface dataset:
In the porcine placenta, aromatase (CYP19) is specifically expressed in trough-like structures of the trophoblast at the basis and flanks of chorionic folds
Authors: KHATRI PERSHOTAM , SCHULER GERHARD , ÖZOCAK-BATMAZ ELÇIN , ÖZALP GÖZDE R.
Published: May 2021

Aromatase was localized in the porcine placenta by immunohistochemistry during the first peak of maternal estrogen concentrations (D25; n=3), their nadir around midgestation (D50; n=3) and their second increase in late gestation (D110; n=3). On D25, aromatase was highly expressed throughout the trophoblast. On D50, its expression was restricted to the trophoblast lining the trough-like fossal regions between the bases of chorionic folds. However, immunostaining was detected only in a minor proportion of these locations, with staining intensity being generally only weak to moderate. On D110, distinct to intense immunostaining was found in virtually all trophoblast fossal regions and in similar structures at the flanks of chorionic folds adjacent to the free margins of secondary and tertiary endometrial folds. A weak staining of questionable specificity was occasionally observed in endometrial glands. In other cell types of the utero-placental compartment, aromatase was undetectable. The results suggest that in pigs placental estrogens could be involved in the formation of a more complex geometry of the feto-maternal interface as pregnancy progresses.
Determination of Serum Nesfatin-1 Level in Healthy Sheep
Authors: AKSOY NEŞE HAYAT
Published: May 2021

Nesfatin-1 is a peptide hormone first documented in studies with rats. It affects appetite control, hunger, fat storage, obesity, water intake, and body temperature. It also plays a role in the regulation of sleep. The lack of knowledge on the level of nesfatin in sheep prompted this study to estimate serum nesfatin concentrations in healthy sheep of different ages and both sexes. Nesfatin values were found to be significantly lower in females than in males. The following differences were observed between the groups: In the female group, the nesfatin level amounted to 5.23 ±1.13 ng/mL in ewes and 3.14 ±0.59 ng/mL in lambs. In the male group, the nesfatin level was 14.31 ±3.94 ng/mL in adults, but higher in male lambs, at 28.83 ±1.72 ng/mL. This preliminary study of serum nesfatin levels in healthy sheep of different ages and both sexes is relevant for future studies and may guide further research on this topic.
Research on factors that influence the course of canine parvovirosis
Authors: WÓJCIK ALICJA , WINIARCZYK STANISŁAW , ADASZEK ŁUKASZ
Published: May 2021

The aim of this study was to demonstrate correlations of the course of canine parvovirus infection and the rate of cytopathic effect (CPE) on CPV-infected CCC clone 81 cell lines with the age of the affected animals, their history of CPV vaccination and the strain of the virus causing the infection. Forty-five dogs with parvovirus confirmed by rapid diagnostic tests and PCR were studied. Faecal samples from diseased animals were used to infect cell lines, which were then observed for a cytopathic effect. The statistical analysis of the results obtained demonstrated a positive correlation between the recovery rate of the diseased animals and the fact that they had been vaccinated against CPV. In dogs that had been vaccinated against CPV, the mean duration of the disease was 6 days, whereas in the group of unvaccinated dogs it was 7 days. The course of the disease also depended on the virus strain. It was shown that dogs from which the CPV-2a strain was isolated took longer to recover, had more severe clinical signs and higher mortality. The cytopathic effect appeared in all infected cultures, while the rate at which changes occurred was independent of the virus strain with which the cells were infected, the age of the dogs from which CPV was isolated and their CPV vaccination history. The study results obtained may serve as valuable prognostic guidelines as to the duration of and recovery from canine parvovirus infection.
Singleton and twin pregnancies in Red Maradi goats: changes in maternal serum biochemical composition and ovarian biometrics at mid gestation
Authors: MBEGBU EDMUND CHIDIEBERE , ANYA KENNETH ORJI , UGWUANYI HILLARY EMEKA , AKANAGA CHUKWUNOMSO EINSTEIN , ABIAEZUTE CLIFFORD NWABUGWU
Published: May 2021

Pregnancy involves some structural and physiological adjustments to achieve an optimal outcome for the fetus and its mother. The magnitude of these changes is influenced by number of fetuses in utero. This research was designed to compare serum biochemical and ovarian morphometric changes associated with singleton and twin pregnancies in Maradi goats. Using Richardson formula, 2.1 × [CRL (cm) + 17], twelve (12) ovarian and blood samples (7 single and 5 twin) from mid gestation (≈70-100 dGA) pregnant goats were purposively selected. Ovarian weights, ovarian diameters, serum biochemistry and levels of ovarian sex hormones were determined and analyzed using standard procedures. Twin pregnant goats had higher (p < 0.05) left ovarian weights, average ovarian weight, left ovarian diameters, average ovarian diameter, serum calcium and inorganic phosphorus levels compared with singleton pregnant goats. There was no significant variation (p > 0.05) in the mean crown-rump length, mean gestational age, mean fetal weight, right ovarian weights, right ovarian diameters, serum concentrations of sodium, potassium, chloride, urea, creatinine, AST, ALT, total protein, estrogen and progesterone between sinlgeton and twin pregnant Red Maradi goats. Ovarian sections from the twin bearing mid gestation goats had more growing follicles and fewer primordial follicles compared with the singleton bearing goats. Findings from this study indicate that twin pregnancy, which could be genetically programmed, has the tendency to affect ovarian follicles development, ovarian morphometrics and calcium metabolism in mid gestation in Red Maradi goats.
TEORES DE VANÁDIO, MOLIBDÊNIO E ANTIMÔNIO EM SOLOS DE DIFERENTES LITOLOGIAS EM SANTA CATARINA
Authors: Suppi Ilana , Campos Mari , Miquelluti David , Machado Matheus
Published: May 2021

VANADIUM, MOLYBDENUM AND ANTIMONY CONTENTS IN SOILS OF DIFFERENT LITHOLOGIES IN SANTA CATARINA. Trace element levels knowledge in soils is important for establishing quality standards. This study has objective to determine levels of vanadium (V), molybdenum (Mo) and antimony (Sb) in soils from Santa Catarina, observing the different source materials and establishing relationships between these elements and soil properties. The extractions occurred according to USEPA 3051 A protocol, with nitric and hydrochloric acid addition for V and Mo and only with hydrochloric acid for Sb. The quantification of V and Mo occurred by inductively coupled plasma optical emission spectrometry and of Sb by hydride generation inductively coupled plasma optical emission spectrometry. The results were submitted to variance analysis and Scott-Knott test and evaluated by Pearson’s correlation with soil attributes. V and Mo contents differed between soils of different source materials. Highest V levels were found in andesite and basalt soils and Mo in porphyry phonolite, granite, mica schist and sedimentary rocks. V and Sb showed a positive correlation with each other and with oxides of iron, silt, and organic carbon. Mo showed a negative correlation with cation exchange capacity (CEC), iron oxides and organic carbon
The Impact of Shopee's Youtube Ads Shopee Version 4.4 Mega Elektronik Sale on Purchase Intention
Authors: Fataron Zuhdan Ady
Published: May 2021

Shopee's e-commerce in recent years has dominated the Indonesian online market because it offers a variety of attractive features. The support for Youtube Ads makes it easier for businesses to offer their products online. Shopee ads are packaged in Youtube Ads with a tagline that can spark consumer interest. One of the Shopee Ad taglines is Shopee 4.4 Mega Elektronik Sale. This tagline is quite booming considering that electronics is a part of modernization which is the basic need of generation Z. This study aims to measure how far the exposure of Shopee's 4.4 version of Shopee's advertisement is. Mega Elektronik Sale: New Refrigerator, Price Slams 50% on student buying interest. The novelty in this study refers to Youtube's capacity as an advertising medium to influence student purchase intentions as the largest market share of electronic products. The research is structured with a quantitative approach with a survey method. The results showed that 44% of students' buying interest was influenced by the Shopee advertisement version of the Shopee 4.4 Mega Elektronik Sale. The Shopee ad version of Shopee 4.4 Mega Elektronik Sale has a positive and significant effect on buying interest with a fairly strong correlation value, namely 0.663 which indicates that the stronger the advertising intensity can directly increase student buying interest.
Development of Tolerance in University Students during Second Language Acquisition
Authors: Kartavtseva Antonina
Published: May 2021

The present research tested various technologies of pedagogical support of tolerance development in students of a technical university during foreign language acquisition. The paper reviews scientific approaches to the essence of tolerance and introduces the stages of its formation, the definitions of pedagogical technology and teaching technology, etc. The author focused on teaching a foreign language in a non-linguistic university and proved that the choice of forms, methods, and technologies depends on a number of circumstances. The research revealed substantive characteristics of tolerance in students and the positive effect of second language acquisition on the parameters of tolerance. The changes in the content characteristics of tolerance were registered on the basis of the corresponding indicators. The study made it possible to determine the effectiveness of the classroom and extracurricular conditions that contribute to the development of tolerance in students of technical universities.
Projected changes in temperature and precipitation over mainland Southeast Asia by CMIP6 models
Authors: Supharatid S. , Nafung J. , Aribarg T.
Published: May 2021

Five mainland SEA countries (Cambodia, Laos, Myanmar, Vietnam, and Thailand) are threatened by climate change. Here, the latest 18 Coupled Model Intercomparison Project Phase 6 (CMIP6) is employed to examine future climate change in this region under two SSP-RCP (shared socioeconomic pathway-representative concentration pathway) scenarios (SSP2-4.5 and SSP5-8.5). The bias-corrected multi-model ensemble (MME) projects a warming (wetting) over Cambodia, Laos, Myanmar, Vietnam, and Thailand by 1.88–3.89, 2.04–4.22, 1.88–4.09, 2.03–4.25, and 1.90–3.96 °C (8.76–20.47, 12.69–21.10, 9.54–21.10, 13.47–22.12, and 7.03–15.17%) in the 21st century with larger values found under SSP5-8.5 than SSP2-4.5. The MME model displays approximately triple the current rainfall during the boreal summer. Overall, there are robust increases in rainfall during the Southwest Monsoon (3.41–3.44, 8.44–9.53, and 10.89–17.59%) and the Northeast Monsoon (−2.58 to 0.78, −0.43 to 2.81, and 2.32 to 5.45%). The effectiveness of anticipated climate change mitigation and adaptation strategies under SSP2-4.5 results in slowing down the warming trends and decreasing precipitation trends after 2050. All these findings imply that member countries of mainland SEA need to prepare for appropriate adaptation measures in response to the changing climate.
Protection of the Interests of Private Investors Through Compliance Control
Authors: Gusev Gleb Mikhailovich
Published: May 2021

This article reveals the term “compliance control” and its role in protection interests of private investors. In the context of international cooperation, the anticipation of risks arising in the process of attracting investments becomes especially important.
Antioxidant Effects of Chalcones during the Inflammatory Response: An Overall Review
Authors: Martins Thaise , Fonseca Bruno M. , Rebelo Irene
Published: May 2021

Reactive oxygen/nitrogen species (ROS/RNS) are produced physiologically by
several mechanisms, especially during the inflammatory response. However, their overproduction
can lead to the evolution of conditions known as oxidative/nitrosative stress,
resulting in the establishment of chronic inflammatory diseases. Chalcones are considered
as a class of flavonoids having the molecular pattern 1,3-diaryl-2-propen-1-one. In the last
few years, the antioxidant property of chalcones has been extensively studied, mainly due
to their ability to inhibit the production or scavenging ROS/RNS. The antioxidant activity
of chalcones, focusing on the production of ROS/RNS during the inflammatory response,
is demonstrated and discussed in the present review. This literature revision was based on
the modulatory effects of chalcones against different enzymes, such as superoxide dismutase
(SOD), nicotinamide adenine dinucleotide phosphate (NADPH) oxidase, catalase
(CAT), myeloperoxidase (MPO) and inducible nitric oxide synthase (iNOS), and, in the
scavenging of ROS/RNS. Whenever possible, the structure-activity relationship (SAR)
was established. Through the analysis accomplished in this review, it can be observed that
the presence of substituents, e.g. hydroxyl, methoxyl, prenyl, and halogen atoms in the
chalcones scaffold, often occurs and can improve their modulatory activities, namely, in
the production of ROS/RNS during the inflammatory response.
Very Early Onset of ATTRE89Q Amyloidosis in a Homozygous Patient
Authors: Russo Massimo , Cucinotta Francescopaolo , Gentile Luca , Fabrizi Gian Maria , Taioli Federica , Vita Giuseppe , Toscano Antonio , Mazzeo Anna
Published: May 2021

Case Presentarion:

Hereditary transthyretin amyloidosis is a progressive, fatal disease that generally involves the peripheral nervous system, the autonomic nervous system, and the heart. It is autosomal dominant with different penetrance depending on the mutation and the genetic background. Many other missense mutations of the TTR gene may cause the disease. Being an overall rare disease is very rare to observe the condition of homozygosity. In particular, cases of homozygosity have been described in patients with ATTRV30M and ATTRV122I amyloidosis. In the former, the phenotype does not seem to be aggravated, having an age of onset and disease course that does not appear to differ from those of heterozygotes, while in the latter, the onset appears to be earlier.

Conclusion:

We report the first case of ATTRE89Q amyloidosis in a patient that was homozygous for the E89Q mutation in the TTR gene. The clinical phenotype resulted in the earlier disease onset reported in this form of amyloidosis, suggesting that the homozygous condition may be prognostically negative.
Studi Parametrik Mortar Geopolimer Hybrid Abu Sawit (Palm Oil Fuel Ash/POFA)
Authors:   Universitas Riau, Yanuari Ramadhan , Ikrammullah Muhammad ,   Universitas Riau, Septari Dinda ,   Universitas Riau, Wijaya Miguel Felix ,   Universitas Riau, Olivia Monita ,   Universitas Riau
Published: May 2021

In this study, the Palm Oil Fuel Ash (POFA) was used as a raw material for making geopolymer mortars that uses a combination of sodium hydroxide (NaOH) and sodium silicate (Na2SiO3). The purpose of this study was to determine the effect of various parameters on the compressive strength of mortars. The parameters involved were namely modulus of activator ratio (Ms 1-3), the molarity of NaOH (10-16M), curing temperature (28-110ºC), type of POFA particle processing (oven-dried, passed the #200 sieve, burned in a brick kiln, burned at 800ºC), rest periods of 3 and 5 days. Based on the parametric study, it was found the optimum mixture with the highest compressive strength consisted of NaOH 14M, Ms ratio of 2.5, curing temperature of 100OC, a rest period of 5 days, particles sieved using #200 sieve and had 15% PCC content.
Analisis Pengaruh Penyekatan Kanal Untuk Untuk Pembahasan Lahan Gambut Tropis
Authors:   Universitas Riau, Khotimah Gina Khusnul , Sutikno Sigit ,   Universitas Riau, Wijatmiko Indradi ,   Universitas Riau
Published: May 2021

Peatlands rewetting for hydrological restoration plays an important role for fire prevention and peatland restoration of degraded peatland. One of the methods for the rewetting is canal blocking. The impact of canal blocking for peatland rewetting is further analyzed in this research. This study focused in Pulau Tebing Tinggi peatland hydrological unit (PHU), which is located in Kepulauan Meranti Regency, Riau Province. To analysis the rewetting impact, 15 dipwells were installed with the distance of 1 m, 51 m, 101 m, 201 and 301 m from the canal for each transect of the three transects. A transect was set in the downstream and two transects were set in the upstream of canal block. The ground water level (GWL) in the 15 dipwells was recorded using water-loggers for one year. This research found that canal blocking has a good effect on maintaining groundwater levels and keeping peatlands in always wet or humid conditions up to a distance of 201 m perpendicular to the canal if the rise in water level in the canal due to canal blocking is more than 0.6 m. It is able to maintain the ground water depth in peatlands around 0.4 m, where the peatlands become low risk to the fire, emission rates and subsidence.
Performance of a Mobile Single-Lead Electrocardiogram Technology for Atrial Fibrillation Screening in a Semirural African Population: Insights From “The Heart of Ethiopia: Focus on Atrial Fibrillation” (TEFF-AF) Study (Preprint)
Authors: Pitman Bradley M , Chew Sok-Hui , Wong Christopher X , Jaghoori Amenah , Iwai Shinsuke , Thomas Gijo , Chew Andrew , Sanders Prashanthan , Lau Dennis H
Published: May 2021

BACKGROUND

Atrial fibrillation (AF) screening using mobile single-lead electrocardiogram (ECG) devices has demonstrated variable sensitivity and specificity. However, limited data exists on the use of such devices in low-resource countries.

OBJECTIVE

The goal of the research was to evaluate the utility of the KardiaMobile device’s (AliveCor Inc) automated algorithm for AF screening in a semirural Ethiopian population.

METHODS

Analysis was performed on 30-second single-lead ECG tracings obtained using the KardiaMobile device from 1500 TEFF-AF (The Heart of Ethiopia: Focus on Atrial Fibrillation) study participants. We evaluated the performance of the KardiaMobile automated algorithm against cardiologists’ interpretations of 30-second single-lead ECG for AF screening.

RESULTS

A total of 1709 single-lead ECG tracings (including repeat tracing on 209 occasions) were analyzed from 1500 Ethiopians (63.53% [953/1500] male, mean age 35 [SD 13] years) who presented for AF screening. Initial successful rhythm decision (normal or possible AF) with one single-lead ECG tracing was lower with the KardiaMobile automated algorithm versus manual verification by cardiologists (1176/1500, 78.40%, vs 1455/1500, 97.00%; P<.001). Repeat single-lead ECG tracings in 209 individuals improved overall rhythm decision, but the KardiaMobile automated algorithm remained inferior (1301/1500, 86.73%, vs 1479/1500, 98.60%; P<.001). The key reasons underlying unsuccessful KardiaMobile automated rhythm determination include poor quality/noisy tracings (214/408, 52.45%), frequent ectopy (22/408, 5.39%), and tachycardia (>100 bpm; 167/408, 40.93%). The sensitivity and specificity of rhythm decision using KardiaMobile automated algorithm were 80.27% (1168/1455) and 82.22% (37/45), respectively.

CONCLUSIONS

The performance of the KardiaMobile automated algorithm was suboptimal when used for AF screening. However, the KardiaMobile single-lead ECG device remains an excellent AF screening tool with appropriate clinician input and repeat tracing.

CLINICALTRIAL

Australian New Zealand Clinical Trials Registry ACTRN12619001107112; https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=378057&isReview=true
The Impact of Inpatient Telemedicine on Personal Protective Equipment Savings During the COVID-19 Pandemic: Cross-sectional Study (Preprint)
Authors: Halabi Reem , Smith Geoffrey , Sylwestrzak Marc , Clay Brian , Longhurst Christopher A , Lander Lina
Published: May 2021

UNSTRUCTURED

With the emergence of the COVID-19 pandemic and shortage of adequate personal protective equipment (PPE), hospitals implemented inpatient telemedicine measures to ensure operational readiness and a safe working environment for clinicians. The utility and sustainability of inpatient telemedicine initiatives need to be evaluated as the number of COVID-19 inpatients is expected to continue declining. In this viewpoint, we describe the use of a rapidly deployed inpatient telemedicine workflow at a large academic medical center and discuss the potential impact on PPE savings. In early 2020, videoconferencing software was installed on patient bedside iPads at two academic medical center teaching hospitals. An internal website allowed providers to initiate video calls with patients in any patient room with an activated iPad, including both COVID-19 and non–COVID-19 patients. Patients were encouraged to use telemedicine technology to connect with loved ones via native apps or videoconferencing software. We evaluated the use of telemedicine technology on patients’ bedside iPads by monitoring traffic to the internal website. Between May 2020 and March 2021, there were a total of 1240 active users of the Video Visits website (mean 112.7, SD 49.0 connection events per month). Of these, 133 (10.7%) connections were made. Patients initiated 63 (47.4%) video calls with family or friends and sent 37 (27.8%) emails with videoconference connection instructions. Providers initiated a total of 33 (24.8%) video calls with the majority of calls initiated in August (n=22, 67%). There was a low level of adoption of inpatient telemedicine capability by providers and patients. With sufficient availability of PPE, inpatient providers did not find a frequent need to use the bedside telemedicine technology, despite a high census of patients with COVID-19. Compared to providers, patients used videoconferencing capabilities more frequently in September and October 2020. We did not find savings of PPE associated with the use of inpatient telemedicine.
Identifying False Human Papillomavirus (HPV) Vaccine Information and Corresponding Risk Perceptions From Twitter: Advanced Predictive Models (Preprint)
Authors: Tomaszewski Tre , Morales Alex , Lourentzou Ismini , Caskey Rachel , Liu Bing , Schwartz Alan , Chin Jessie
Published: May 2021

BACKGROUND

The vaccination uptake rates of the human papillomavirus (HPV) vaccine remain low despite the fact that the effectiveness of HPV vaccines has been established for more than a decade. Vaccine hesitancy is in part due to false information about HPV vaccines on social media. Combating false HPV vaccine information is a reasonable step to addressing vaccine hesitancy.

OBJECTIVE

Given the substantial harm of false HPV vaccine information, there is an urgent need to identify false social media messages before it goes viral. The goal of the study is to develop a systematic and generalizable approach to identifying false HPV vaccine information on social media.

METHODS

This study used machine learning and natural language processing to develop a series of classification models and causality mining methods to identify and examine true and false HPV vaccine–related information on Twitter.

RESULTS

We found that the convolutional neural network model outperformed all other models in identifying tweets containing false HPV vaccine–related information (F score=91.95). We also developed completely unsupervised causality mining models to identify HPV vaccine candidate effects for capturing risk perceptions of HPV vaccines. Furthermore, we found that false information contained mostly loss-framed messages focusing on the potential risk of vaccines covering a variety of topics using more diverse vocabulary, while true information contained both gain- and loss-framed messages focusing on the effectiveness of vaccines covering fewer topics using relatively limited vocabulary.

CONCLUSIONS

Our research demonstrated the feasibility and effectiveness of using predictive models to identify false HPV vaccine information and its risk perceptions on social media.
Protocol for stepped wedge cluster randomized trial to evaluate the effects of SurgeCon: A quality improvement emergency department surge management platform (Preprint)
Authors: Mariathas Hensley , Asghari Shabnam , Hurley Oliver , Anaraki Nahid , Young Christina , Aubrey-Bassler Kris , Wang Peter , Gadag Veeresh , Nguyen Hai Van , Etchegary Holly , McCrate Farah , Knight John
Published: May 2021

BACKGROUND

Despite many efforts, long wait time and overcrowding at Emergency Departments (EDs) have remained a significant health system issue in Canada. For several years, Canada has had one of the longest wait times among Organisation for Economic Co-operation and Development OECD countries. From the patient’s perspective, the challenge has been described as “patients wait in pain or discomfort for hours before being seen at EDs”. In this study, we propose an innovative quality-improvement intervention called SurgeCon that includes a protocol-driven software platform and several other initiatives to reduce wait times and improve the sustainability of health systems without significant workforce changes. We piloted SurgeCon at an ED in Carbonear, Newfoundland and Labrador (NL) and found there was a 32% reduction in ED wait time.

OBJECTIVE

Our primary objectives of the trial are to evaluate the effects of SurgeCon on ED performance based on length of stay (LOS), time to physician’s initial assessment (PIA), and the number of patients leaving the ED without being seen by a physician (LWBS), patient satisfaction and patient-reported experience with ED wait times. The ultimate goal of this study is to create better value care by reducing the per-patient cost of delivering ED services.

METHODS

This study will investigate the effects of SurgeCon on health system key performance outcomes and patient-reported experience and satisfaction. The study uses a comparative effectiveness-implementation hybrid design. This type of hybrid design has been recommended to help achieve rapid translational gains that can hasten the movement of interventions from research to practice to public health impact. In our hybrid design, we will use a pragmatic stepped wedge cluster randomized trial (SW-CRT) design that enrols four 24/7 on-site ED physician support (category A) hospitals into a 30-month trial. All clusters (hospitals) start with a baseline period of “usual care” and are randomized to determine the order and timing of transitioning to “intervention care” until all hospitals are exposed to the intervention condition for the remainder of the study.

RESULTS

Data collection for this study is ongoing. To date, 15 randomly selected patients have participated in telephone interviews concerning patient-reported experiences and patient satisfaction with ED wait times.

CONCLUSIONS

By evaluating the mechanisms behind the use of SurgeCon, we hope to be able to improve wait times and create better value ED care in this healthcare context.

CLINICALTRIAL

This study is registered in ClinicalTrials.gov NCT04789902
Antecedents and Implications of Innovation Capability: Empirical Study of Bakpia MSMEs in Yogyakarta
Authors: Nurhayati Baroroh , Kusmantini Titik , Wahyuningsih Tri
Published: May 2021

Introduction/Main Objectives: This research examines the antecedents and implications of innovation capability, empirically. The outcomes aim at contributing to the knowledge and understanding about the main driver of innovation capability.  Background Problems: Yogyakarta is known for its many and varied charms, its tourist attractions, the availability of facilities and infrastructure to support tourism, such as souvenir sellers. But there is known that number of total foreign and domestic tourists has been a decrease in 2018 (Semester I by 11.51% and II by 3.33%), also in 2019 (Semester I by 11.23%). This is a challenge for MSMEs in the tourism sector and MSMEs in other sectors that support tourism, such a souvenir seller. Bakpia is one of the well-known products of the food and beverage sector in Yogyakarta often bought for souvenirs. The Bakpia MSMEs’ innovations were triggered by competition among the Bakpia producers in Yogyakarta. Therefore, every Bakpia MSME must be competitive to survive in the market. Thus, there is a need to improve their innovation capability, which will impact the innovation performance of the Bakpia MSMEs in Yogyakarta. There is a gap in the research regarding the influence of the factors that are predicted to build innovation capability. Novelty: Previous studies’ results indicate that the influence of knowledge donating and knowledge collecting about innovation performance is not yet conclusive. Therefore, this study aims to fill the gap in the previous research by examining the role of capability as a mediating between knowledge sharing process (knowledge donating and knowledge collecting) to innovation performance. Research Methods: Forty-eight items of data were obtained from Bakpia MSMEs in Yogyakarta through a survey conducted by distributing questionnaires directly to them. The data were analyzed using PLS-SEM via SmartPLS version 3.3.2. Findings/Results: This study shows that the direct and indirect effects of sharing knowledge (which includes donating and collecting knowledge) about innovation performance are found to be positive but not significant. The results also indicate that innovation capability does not significantly mediate knowledge donating and knowledge collecting about innovation performance. Meanwhile, the influence of innovation capability on innovation performance was found to be positive and significant. Conclusion: The antecedents are insignificant for innovation capability, but the antecedent’s constructs still act as a driver to build innovation capability.
Determinant Factors for Community Participation in Dutungan Island of Barru Regency
Authors: Junaid Ilham
Published: May 2021

Understanding determinant factors in community participation is essential in encouraging community participation in tourism activities. However, community participation studies mainly focused on identifying community participation issues and reasons to advocate community participation. This research aims at 1) exploring factors that affect community participation in tourism, and 2) proposing strategies to encourage active participation by the local community. This paper employs a qualitative methodology conducted in 2019. The research reveals that community participation around Dutungan Island has three categories: supportive participation, micro business-based creation participation and passive participation. The determinant factors for community participation include; 1) private management of tourism attraction; 2) lack of collective awareness by the local community, and 3) lack of skills and knowledge in tourism. This paper proposes the importance of implementing communitybased tourism village; strengthening cooperation between the owner or manager of Dutungan Island and the local community; and optimising Dutungan Island management’s role to help the local people who reside the village. Dutungan Island’s manager should be able to share profit to help the local people through social programs that may include training for the local people and providing investment for micro business. This paper provides insight into how to encourage community participation through the role of different stakeholders, including the island and the local community.
De sobrevivir a vivir
Authors: Hernández Alvarado Miguel Ángel
Published: May 2021

A lo largo de todo el período de contingencia, la cotidianeidad ha cambiado, al pasar por situaciones que la llevan de un lado a otro, agotando la expectativa de volver a la antigua normalidad, que se ve cada vez más lejana. En esta nostalgia por cómo eran las cosas, la constante ha sido adaptarse a lo que ocurre, a los eventos que suceden y sorprenden, así como a los cambios, con sus consecuencias de diversas dimensiones.
Marked differences in local bone remodelling in response to different marrow stimulation techniques in a large animal
Authors:   308A Stemmler Hall, 3450 Hamilton Walk, Philadelphia, PA, 19104-6081, USA, Zlotnick HM , Locke RC , Stoeckl BD , Patel JM , Gupta S , Browne KD , Koh J , Carey JL , Mauck RL
Published: May 2021

Marrow stimulation, including subchondral drilling and microfracture, is the most commonly performed cartilage repair strategy, whereby the subchondral bone plate is perforated to release marrow-derived cells into a cartilage defect to initiate repair. Novel scaffolds and therapeutics are being designed to enhance and extend the positive short-term outcomes of this marrow stimulation. However, the translation of these newer treatments is hindered by bony abnormalities, including bone resorption, intralesional osteophytes, and bone cysts, that can arise after marrow stimulation. In this study, three different marrow stimulation approaches – microfracture, subchondral drilling and needle-puncture – were evaluated in a translationally relevant large-animal model, the Yucatan minipig. The objective of the study was to determine which method of marrow access (malleted awl, drilled Kirschner wire or spring-loaded needle) best preserved the underlying subchondral bone. Fluorochrome labels were injected at the time of surgery and 2 weeks post-surgery to capture bone remodelling over the first 4 weeks. Comprehensive outcome measures included cartilage indentation testing, histological grading, microcomputed tomography and fluorochrome imaging. Findings indicated that needle-puncture devices best preserved the underlying subchondral bone relative to other marrow access approaches. This may relate to the degree of bony compaction occurring with marrow access, as the Kirschner wire approach, which consolidated bone the most, induced the most significant bone damage with marrow stimulation. This study provided basic scientific evidence in support of updated marrow stimulation techniques for preclinical and clinical practice.
Das metamorfoses do amor n’Os Lusíadas: arma-amar
Authors: Costa Mariana Caser da
Published: May 2021

A leitura detida dos dez cantos constitutivos de Os Lusíadas permite-nos associar o substantivo arma e a forma verbal amar a questões que excedem a casualidade textual ou a ludicidade proveniente da mudança de posição da letra r. Tematicamente, sabemos que “as armas e os barões assinalados” cedem, algumas vezes, espaço ao lirismo, por exemplo, na voz de um ca- pitão que parece deixar sua patente, suas armas, portanto, para armar es- petáculos cujo protagonista é o amor. Este artigo pretende pensar sobre a forma como esse jogo de palavras transforma não apenas o campo vocabu- lar, mas, especialmente, o semântico, na extensão do poema: quais efeitos causa na leitura; quais leituras podem ser feitas, contemporaneamente; em que implica a relação entre arma e amar. Ao refletir sobre essas questões a partir das ideias de António Saraiva, Eduardo Lourenço, Luiza Nóbrega, bem como do escritor português contemporâneo Mário Cláudio, dentre outros nomes de relevo no cenário da crítica e da teoria literárias, não pre- tendemos gerar uma interpretação inovadora do poema, mas reforçar a leitura atual d’Os Lusíadas, em que demandas maneiristas, lúdicas e, espe- cialmente, denotadoras da plasticidade do texto, ressurgem como pontos de relevo na exegese da obra.
A busca da linguagem na mudez dos incêndios em Lídia Jorge e Clarice Lispector
Authors: Castro Ana Maria Vasconcelos Martins de
Published: May 2021

Deparamo-nos, no conto “Marido”, de Lídia Jorge, e na peça “A pecadora queimada e os anjos harmoniosos”, de Clarice Lispector, com duas mulhe­res que, se viveram abafadas, encontram na morte uma última e dolorosa possibilidade de fala e de poder. Se é verdade que ambas morrem numa luta inglória e desigual com o masculino, também é patente o esforço por encontrar, da sombra à qual foram subjugadas, um lugar onde a respiração seja possível no mundo falocêntrico.
Memórias de uma geração da utopia, ou da esperança como princípio
Authors: Abdala Jr. Benjamin
Published: May 2021

A geração da utopia, de Pepetela, é um romance autoficcional: o narrador disserta ficcionalmente a partir de fatos e da ambiência diretamente vividos pelo autor. São problematizadas, em cada momento do processo da luta de libertação nacional de Angola, as reais motivações dos revolucionários, antes e depois da independência do país. Os revolucionários se motivaram por uma perspectiva ampla de libertação, para além da nacional: a social. Entretanto, como em toda a travessia, o ponto atingido na outra margem não foi exatamente o sonhado. E as formas opressivas do colonialismo aca­baram por enredar, com novas roupagens, a Angola liberta, dando origem a perspectivas distópicas, contrárias à utopia revolucionária.
Intertextualidade e memória literária: a leitura como prática de memória em Rui Knopfli
Authors: Meloni Otavio Henrique
Published: May 2021

Escrita e leitura são práticas indissociáveis, bastante íntimas e reveladoras de um profundo exercício de memória. Por mais pessoal que seja tal exer­cício, a memória sempre compartilha e associa fragmentos da esfera íntima com aspectos sociais e culturais. Por isso, quando pensamos na memória que é construída por intermédio das leituras de um indivíduo, temos vá­rias esferas de pensamento e reflexão sobre uma mesma realidade, ainda que transformada por seu olhar de leitor. Este trabalho pretende discutir o papel das memórias literárias na construção do universo poético do mo­çambicano Rui Knopfli, levando em consideração sua condição de “dester­ritorializado” e a necessidade de afirmar um local de pertença (a leitura) como passível de referência. Tal local de segurança se fortalece na junção da memória literária com a intertextualidade que ela provoca. Acredita­mos, assim, que as memórias literárias assumem o papel de local de per­tença para o sujeito poético do moçambicano, amenizando suas fraturas de naturalidade, afirmando e justificando a existência deste sujeito por meio de sua experiência de leitura.
A inútil poesia: breve análise da poesia de Luís Quintais
Authors: Moreira Deyse dos Santos
Published: May 2021

Assinalados de cinza e permeados por uma presença imprecisa da melan­colia, os versos de Luís Quintais nos apresentam um mundo tecido de ima­gens fragmentadas, quotidiano opaco cujo espaço e tempo são interrom­pidos por vazios. Mas que vazios são esses? Estas páginas, oriundas dessa questão, em seu buscar respostas, depararam-se com outra dúvida: afinal, por que muitas das poéticas atuais, das quais a poesia de Luís Quintais faz parte, dão protagonismo à palavra, pincelando nos versos uma reflexão so­bre a linguagem poética e a sua (in)utilidade e poder de resistência face à sociedade do seu tempo? Assim, quando lemos a poesia de Luís Quintais, observamos que a função metalinguística é fundamental para compreen­der, em seus poemas, o sentimento de vazio que, por sua vez, levam-nos a uma reflexão sobre a linguagem, a memória e a história.
Banquetes, manjares desusados
Authors: Maffei Luis
Published: May 2021

O Canto VI d’Os Lusíadas apresenta algumas das questões centrais do po­ema. Uma delas diz respeito a uma série de desdobramentos que se anun­ciam nesse ponto da narrativa, a partir de dicotomias que opõem, apa­rentemente, gozo alimentar x valor sacrificial, por exemplo, para explodir em lugares futuros. Os manjares e os banquetes são lugares de partida, e também de chegada, de muito dessa discussão, que envolve Veloso, Vênus, Baco, vinho, amor, etc.
A comida recriada pela literatura portuguesa: entrevista a Carlos Reis
Authors: Calvão Dalva , Figueiredo Monica
Published: May 2021

Entrevista a Carlos Reis.
Por uma literatura infantil portuguesa: Aquilino Ribeiro e Matilde Rosa Araújo
Authors: Ruas Luci
Published: May 2021

Meu propósito é mostrar que, no século XX, especificamente na sua segun­da metade, muitos dos textos que se produzem para crianças já mostram evidente preocupação em descolar-se do destinatário, para que se dê im­portância ao como se constroem, isto é, para que a escrita se faça escritura e o texto literatura. Para isso, começamos por apresentar as preocupações de Antero de Quental e Eça de Queirós para depois abordar o trabalho literá­rio de Aquilino Ribeiro, especificamente O romance da raposa, passando, em seguida à abordagem da obra de Matilde Rosa Araújo.
Infância e história nos romances de João Paulo Borges Coelho
Authors: Can Nazir Ahmed
Published: May 2021

Focando As Duas Sombras do Rio, As Visitas do Dr. Valdez e Crónica da Rua 513.2, pretendemos demonstrar como a infância possui dois tipos de funções na estética de João Paulo Borges Coelho. Simultaneamente retros­pectivo e prospectivo, sinalizando tanto uma singularidade (fugaz) quanto uma opressão (permanente), o tempo das crianças representado nestes ro­mances liga-se a uma específica e desencantada visão sobre a história.
Territórios da infância em Ondjaki: uma estética da pós-colonialidade angolana
Authors: Coutinho Fernanda , Nascimento Marlúcia Nogueira do
Published: May 2021

Considerando a infância uma categoria epistemológica que dá margem a muitas indagações sobre as representações sociais na contemporaneidade, abordamos, neste trabalho, uma leitura da obra do prosador e poeta ango­lano Ondjaki (Ndalu de Almeida), por meio da perspectiva da voz infantil que predomina em vários de seus textos. Fundamentados em Agamben (2005) e Spivak (2010), buscamos verificar como essa (ante)voz in-fante, em textos ficcionais e não ficcionais do escritor luandense, percebe e repre­senta o contexto da pós-colonialidade angolana. Para isso, foram selecio­nadas obras de Ondjaki publicadas na primeira década deste século XXI, momento em que o autor afirma-se como intelectual e como ficcionista.
Vozes emudecidas: pode o subalterno falar? (Uma leitura do conto “Tio me dá só cem”, de João Melo)
Authors: Lima Danuza Américo Felipe de , Valentim Jorge Vicente
Published: May 2021

Propomos, neste ensaio, uma análise do conto de João Melo “Tio me dá só cem”, que faz parte do livro de contos Filhos da Pátria (2001), pautados na teoria pós-colonial e nos pressupostos teóricos abordados por Gayatry Spivak sobre a questão da subalternidade e os sujeitos emudecidos pelos discursos oficiais. Importa-nos, aqui, perceber os recursos utilizados pelo escritor angolano na efabulação de infâncias sob o ponto de vista da crian­ça no contexto do abandono social.
Imagens, narrativas e agenciamento. Ensaiando abordagens transdisciplinares sobre representação, infância e género
Authors: Brugioni Elena
Published: May 2021

A partir dos acontecimentos relacionados com a campanha #BringBackOur Girls, procura-se esboçar uma reflexão crítica e conceptual pautada por um contraponto entre imagens fotográficas e narrativas escritas, problematizando as práticas de representação do sujeito subalterno e o seu agenciamento. Encarando a intersecção entre infância e género como lugar matricial de uma narrativa subalterna, procura-se reflectir em torno da relação entre sujeito e objecto que as representações – escrita e visuais – da infância subentendem e convocam.
Comunidade e imunidade pós-colonial: o campo literário e cultural nos espaços da língua portuguesa
Authors: Coutinho Alexandre Montaury Baptista
Published: May 2021

O texto propõe uma sistematização preliminar do quadro de relações literárias e culturais formadas entre artistas e intelectuais angolanos, brasileiros, moçambicanos e portugueses no âmbito das lutas políticas da modernidade do século XX. Partindo do pressuposto de que essas relações geraram um campo cultural específico que configurou e reconfigurou sentidos de comunidade, pretende-se reconstituir a formação de redes intelectuais que, à margem das instituições oficiais, no plano da escrita literária ou da intervenção cultural, se posicionaram frente a desafios políticos comuns nos últimos sessenta anos.
‘Barranco de Cegos’: o homem e a história na “Torre dos quatro ventos”
Authors: Serra José Pedro
Published: May 2021

Barranco de Cegos não é apenas um romance neo-realista de intervenção político-ideológica. No conflituoso universo rural desenhado, onde se manifestam poderosas e ancestrais forças ctónicas, são as questões da vida, da morte, da alteridade, do sentido que estão presentes.
Cabral aporta em Portugal: poesia brasileira lida pela crítica portuguesa atual
Authors: Bosi Viviana
Published: May 2021

Pretendemos comentar leituras realizadas pela crítica portuguesa atual acerca da poesia brasileira moderna, enfocando, no âmbito deste artigo, ensaios recentes sobre João Cabral de Melo Neto. Na introdução, fazemos um breve apanhado sobre a situação do ensino da literatura brasileira em Portugal hoje.
A materialidade poética de Gonçalo M. Tavares
Authors: Espínola Paloma Roriz
Published: May 2021

A arquitetura não raro se empresta a um diálogo com a literatura, como ve­mos na apropriação que dela já fizeram alguns escritores, como Paul Valéry e João Cabral de Melo Neto, a partir de uma recriação do mito de Anfion. O escritor angolano-português Gonçalo M. Tavares propõe, através de dois textos, Arquitetura, natureza e amor e A estranha casa do senhor Walser, uma aproximação entre o ofício do escritor e o do arquiteto. O objetivo deste artigo é o de mostrar como a proposição de Gonçalo M. Tavares em torno desta aproximação poderia se refletir numa poética baseada na busca de um caráter material da linguagem, mais especificamente nos poemas que compõem o seu livro intitulado 1, poética a qual se tentará articular as ideias de uma “lucidez emotiva” de Roland Barthes e a de “moção” de Georges Didi-Huberman.
Distribution of 137Cs and 40K in the Bottom Sediments of the Balaklava Bay (the Black Sea)
Authors: Kremenchutskii D. A. ,   Marine Hydrophysical Institute, Russian Academy of Science, Sevastopol, Russia, Gurov K. I. ,   Marine Hydrophysical Institute, Russian Academy of Sciences, Sevastopol, Russia
Published: May 2021

Purpose. The aim of the work is to study spatial variability of the 137Cs and 40K concentrations in the bottom sediments of the Balaklava Bay, and to estimate the sedimentation rate and relative content of the biogenic fraction. Methods and Results. The results of the 137Cs and 40K concentration measurements in 5 columns of the bottom sediments sampled in various parts of the Balaklava Bay are represented. Activity of 137Cs and 40K in the samples was determined by the gamma spectrometric analysis. Based on the measurement data, spatial variability of the 137Cs and 40K concentration fields in the bottom sediments was studied, and the sedimentation rate was quantitatively estimated. Application of the balance equation provided quantitative estimates of the relative biogenic fraction content; its spatial variability was described. Quantitative estimates of the relationship between the biogenic fraction estimates resulted from use of the direct and indirect methods are represented. Conclusions. According to the obtained results, the 137Cs and 40K concentrations in the upper 5 cm layer of bottom sediments varied in space from 11 to 62 and from 155 to 562 Bq/kg, respectively. The maximum radionuclide concentrations were characteristic of the northern part of the bay, the minimum ones – of its southern part. The sedimentation average rate was 0.51 ± 0.06 cm/year. Relative biogenic fraction content in the sediments varied in space from 30 to 89% and averaged 46 ± 25%. The maximum values were observed in the southern part of the bay, the minimum ones – in the northern part.