bluuebunny/crossref_metadata_2025 huggingface dataset:
Influence of immunological nutrition on treatment of patients with oncological profile
Authors: Katrichenko M. O. , Lisnyi I. I.
Published: July 2018

In the reviewed article, we consider epidemiological and laboratory data that confirm the protective effects of biologically active nutrients in our diet for various diseases. Along with various factors such as alcohol, smoking, nutrition plays a vital role in influencing the patient’s immune response by transforming cells or by preventing, or acceleration of malignancy. Many data suggest that immunoactive nutrients control inflammatory and precancerous reactions in immune cells. Immunoprophylaxis is usually associated with modulation of the immune response when inflamed, thereby improving clinical outcomes. Different nutrients, including glutamine, arginine, vitamins, minerals and long-chain fatty acids, are important components of immunological nutrition. Clinical studies associated with these substances show different results with minimal effect. However, some studies have shown that these nutrients may have immunomodulatory effects that can reduce the risk of developing cancer. Pre-clinical studies claim that most of these nutrients have a positive effect in the complex treatment of cancer patients. In this article, we will consider the effect of the above nutrients on the immune system in patients of oncologic profile.

Recent evidences suggest that immunological nutrition plays an important role in the development of cancer and its progression. Data from animal studies have clearly shown that the use of immunomodulatory nutrients isolated from food, by launching a cascade of immunological reactions, can detect and eliminate the tumor. Although the technology has evolved to such an extent that we can study each individual cytokine or function of the immune cell, it is difficult to demonstrate the powerful role of the immune system in preventing or treating cancer due to the complexity of the tumor cell or heterogeneity in different patients' populations. However, the study sheds light on interactions in immune responses and cancer development, prevention and therapeutic strategies that involve modulation through biologically active agents.
Intensive therapy in patients with scar strictures of the esophagus
Authors: Shaprynskyi V. O. , Shaprynskyi Y. V. , Kryvetskyi V. F. , Hussein Mustafa Bassam
Published: July 2018

The proposed medical tactics and intensive therapy of scar strictures of the esophagus we represent in this article. The causes of their occurrence: burns in the esophagus, surgical interventions on the esophagus, reflux esophagitis, and malignant genesis – esophageal cancer. A considerable part of patients with scar strictures of the esophagus is hospitalized at later stages of the stricture: with 4th and 5th degrees of obstruction. This leads to increasing of the number of exhausted patients and neglected cases, that contributes to increasing of levels of postoperative lethality and complications. The sults of surgical treatment of 116 patients with esophageal strictures at the period of 2003–2017 were analyzed. We used a logistic regression method to determine the risk factors for postoperative complications. It was established that the risk increases significantly with the presence of technical difficulties during operation, diabetes mellitus, blood plasma albumin levels less than 25 g/l, complete obstruction of the esophagus. The proposed program of treatment of patients with scar strictures of the esophagus reliably reduces the risk of postoperative complications. The diagnostic algorithm, the program of treatment of patients with preoperative infusion therapy and parenteral nutrition with “all in one” system were applied in patients of the main group. Due to the treatment program and intensive therapy, the number of postoperative complications has decreased from 27,27% to 12,0%, and mortality – from 6,06% to 2,0%.
Practical aspects of use of emergency sonography for differential diagnosis of critical respiratory incidents (Blue-protocol “Bedside Lung Ultrasound in Emergency”)
Authors: Valenko O. O. , Volkov O. O. , Bessarab A. S.
Published: July 2018

This article contains rather motivating than teaching information. It is a synthesis of analysis of authoritative global scientific publications and personal experience. The modern approaches to diagnosis of critical respiratory incidents using ultrasound, superficial theoretical review of the core of the method and our own experiences regarding effective protocol of sonographic lung assessment are presented here. Several interesting clinical cases emphasize the advantages of routine use of diagnostic ultrasound in patients with critical uncompensated respiratory disaster as well as in sub-compensated and compensated patients.

The main principles of bedside lung ultrasound in emergency that should encourage wider implementation and use of this method by doctors of different specialties are: “Lung ultrasound is very easy to perform using simple equipment”, and “BLUE-protocol is a simple protocol that allows quick (< 3 min) diagnosis of the cause of respiratory failure”.

Lung sonographic assessment allows not only to determine quickly the cause of critical respiratory failure and counteract it starting the etiotropic treatment as soon as possible, but also visualize the dynamics of pathological changes in response to therapy, thus allowing us to evaluate its effectiveness properly.

The use of ultrasound in diagnosing enables more adequate decision making regarding the need of interventional therapy. It also leads to setting the right diagnosis faster, improving the quality of medical care, shortening the length of stay of patients in ICU, decreasing the total cost of the treatment.

Identification and analysis of the amount of sonographic signs “B-lines – lung rockets” provides an opportunity to measure the volume/amount of interstitial lung fluid properly and track this marker/indicator in dynamics in response to the treatment.

The unified method of protocolized assessment should be used within one medical facility in order to boost effectiveness and make evaluation and dynamic evaluation of pathological changes more objective by the same one or different medical specialists.

Diagnostic ultrasound has a very low cost and there is no radiation exposure to patients which allows performing as many examinations as needed, without limitations.
MODEL MEDIA PEMBELAJARAN E-KOMIK UNTUK SMA
Authors: Aeni Wiwik Akhirul , Yusupa Ade
Published: July 2018

The development of learning media model becomes a necessity for improving the quality of education in Indonesia. Following the development of technology and information, new models continue to be developed, one of which is comic. This study aims to develop a model of electronic comic (e-Comic) as a medium of learning. With the ADDIE development method, it is done through needs analysis, model design, prototype development, prototype implementatio (testing) and evaluation of prototype implementation results to the field. The result is a comic electronic model in which graphic-shaped graphics are highlighted to deliver learning materials in accordance with the applicable curriculum. The material is delivered in story form so the delivery is not rigid. Implementation of field trial prorotype obtained data that the user liked the model of this e-Comic learning media and feel like learning to read comics with digital format. The conclusion of the development of e-Comic model, innovative learning media, fun, effective and efficient, so as to increase the students' attention in understanding the subject AbstrakPengembangan model media pembelajaran menjadi kebutuhan untuk peningkatan kualitas pendidikan di Indonesai. Mengikuti perkembangan teknologi dan informasi, model-model baru terus dikembangkan dari waktu ke waktu. Komik yang dimaknai sebagai sebuah gambar kartun berteks mampu menyampaikan sebuah pesan dengan gaya yang ringan dan menyenangkan.Tujuan pembuatan model ini untuk membuat sebuah model berformat elektronik komik (E-komik) sebagai media pembelajaran menyampaikan materi pendidikan. Dengan metode pengembangan ADDIE, yang dimulai dengan kegiatan Analisis Kebutuhan, Desain/Perancangan Model, Development Prototype, Implementasi Prototype berbentuk ujicoba prototype ke user dan dilanjutkan dengan Evaluasi hasil implementasi prototype ke lapangan model Elektronik komik ini dikembangkan. Hasil dari pengembangan ini adalah sebuah model elektronik komik yang didalamnya berupa grafis berbentuk kartun ditonjolkan untuk menyampaikan materi-materi pembelajaran sesuai dengan kurikulum yang berlaku di sekolah. Materi disampaikan dalam bentuk cerita sehingga penyampaiannya tidak kaku. Implementasi ujicoba prorotype dilapangan diperoleh data bahwa user menyukai model media pembelajaran E-komik ini dan merasa belajar seperti membaca komik dengan format digital. Kesimpulan pengembangan model E-komik yang dilakukan menjadi salah satu jawaban atas kebutuhan terhadap media pembelajaran yang inovatif, menyenangkan, efektif dan efisien, sehingga dapat meningkatkan perhatian siswa dalam memahani mata ajar. Untuk itu penerapannya dapat dilakukan secara bertahap pada SMA tertentu.
MEDIA LITERASI BAGI DIGITAL NATIVES: PERSPEKTIF GENERASI Z DI JAKARTA
Authors: Rastati Ranny
Published: July 2018

In 2017 the majority of internet users are 19-34 years old or 49.52% (APJI, 2017). Almost half of the internet users in Indonesia are digital natives who were born after 1980: Generation Y (1980-1995) and Generation Z (1996-2009). This research will be focused on Generation Z as the true generation of the internet. Generation Z was born when the internet is available, a contrast to Generation Y who is still experiencing the transition of the internet. The purpose of this research is to find an effective way of providing information about media literacy to Generation Z. Through descriptive qualitative, the study was conducted with in-depth interview and observation toward 12 university students in Jakarta. The results showed that there are four effective ways of providing information about media literacy which is i) videos distributed to social media such as Youtube and Instagram, ii) interesting memes in communicative style, iii) through selebgram or micro-celebrity in Instagram who is consider as a role model and have a positive image, and iv) roadside billboards. Another interesting finding is that male informants tend to like media literacy information through videos and memes, while female informants prefer campaigns conducted by positive image selebgram and billboard. AbstrakPada tahun 2017 pengguna internet di Indonesia mayoritas berusia 19-34 tahun yaitu sebanyak 49,52% (APJI, 2017). Dari data tersebut terlihat bahwa hampir sebagian pengguna internet di Indonesia adalah digital natives atau penutur asli teknologi digital yaitu orang-orang yang lahir setelah tahun 1980: Generasi Y (1980-1995) dan Generasi Z (1996-2009). Penelitian ini akan difokuskan kepada Generasi Z karena mereka dianggap sebagai sebenar-benarnya generasi internet. Generasi Z lahir saat teknologi tersebut sudah tersedia, berbeda dengan Generasi Y yang masih mengalami transisi teknologi hingga menuju internet. Tujuan penelitian ini adalah mencari tahu cara yang efektif dalam memberikan informasi mengenai media literasi kepada generasi Z. Metode yang digunakan adalah deskriptif kualitatif dengan observasi dan wawancara mendalam. Informan berjumlah 12 orang mahasiswa di Jakarta. Hasil penelitian menunjukkan bahwa ada empat cara yang efektif dalam memberikan informasi mengenai media literasi yaitu i) video yang disebarkan ke media sosial seperti Youtube dan Instagram, ii) meme menarik dengan bahasa yang mudah dimengerti, iii) melalui selebgram yang menjadi panutan dan berimage positif, dan iv) papan iklan di pinggir jalan. Temuan menarik lainnya adalah informan laki-laki cenderung menyukai informasi media literasi melalui video dan meme yang disebarkan ke media sosial, sementara perempuan lebih menyukai kampanye yang dilakukan oleh selebgram berimage positif dan papan iklan.
Synthesis, Crystal Structure and Biological Evaluation of Novel 2-Phenylthiazole Derivatives as Butyrylcholinesterase Inhibitors
Authors: Shi Da-Hua , Ma Xiao-Dong , Liu Yu-Wei , Min Wei , Yin Fu-Jun , Tang Zong-Ming , Song Meng-Qiu , Lu Chen , Song Xiao-Kai , Liu Wei-Wei , Dong Tong
Published: July 2018

To find novel butyrylcholinesterase inhibitors, three novel 2-phenylthiazole derivatives were synthesised. The synthesised compounds were characterised by NMR and single-crystal X-ray diffraction analysis. Hirshfeld surface analysis and two-dimensional fingerprint plots of the compounds were used as a theoretical approach to assess the driving force for crystal structure formation via the intermolecular interactions in the crystal lattices of the synthesised compounds. Among the three compounds, N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro- 1H-pyrazol-4-yl)-2-(4-methoxyphenyl)thiazole-4-carboxamide showed the best butyrylcholinesterase-inhibition activity with an IC50 value of 75.12 μM. A docking study demonstrated that this compound interacts with the peripheral anionic site of butyrylcholinesterase.
PERUBAHAN FUNGSI LINGKUNGAN TERBANGUN DI KORIDOR JALAN CIGONDEWAH KOTA BANDUNG
Authors: Wijaya Karto
Published: July 2018

Abstract:. Cigondewah road corridor is an area that has wide potential especially in the development of tourism trade of Bandung, especially in the leading product sector of textile industri. Home-based economic activities of the industri that has been done since the 1960s has contributed income, especially for residents of Cigondewah area, because labor comes from the residents of the three villages themselves. In early 1997 the Cigondewah area was able to serve as a fabric trading center. This center serves buyers who come from Bandung and surrounding areas. This area in RTRW Bandung City 2013 is environmentally friendly industrial area. The development of this area provides a wide potential especially in its development as an area that has excellent products within the scope of Bandung tourism development plan. This study aims to provide an overview of the facts and phenomena that occur in the Cigondewah Area Bandung. Thus the research method used is qualitative descriptive research. This research is intended to describe or describe the phenomena that exist in the field such as shape, activity, characteristics, changes, relationships, similarities and differences of phenomena so that in this study is not done manipulation only describe according to reality or an existing condition location.Keyword: The changes of Built Environment Function, Corridor Development, EnvironmentAbstrak: Koridor jalan Cigondewah adalah kawasan yang memiliki potensi yang luas terutama dalam pengembanga pariwisata perdaganagn Kota Bandung khususnya pada sektor produk unggulan industri tekstil. Kegiatan ekonomi berbasis home industri yang telah dilakukan sejak tahun 1960-an ini telah memberikan kontribusi pendapatan khususnya bagi penduduk kawasan Cigondewah, karena tenaga kerja berasal dari penduduk ketiga kelurahan itu sendiri. Pada awal 1997 kawasan Cigondewah mampu berperan sebagai sentra perdagangan kain. Sentra ini melayani pembeli-pembeli yang berasal dari Bandung dan sekitarnya. Kawasan ini dalam RTRW Kota Bandung 2013 adalah kawasan industri berwawasan lingkungan. Perkembangan kawasan ini memberikan potensi yang luas terutama dalam pengembangannya sebagai sebuah kawasan yang memiliki produk unggulan dalam cakupan rencana pengembangan pariwisata Kota Bandung. Penelitian ini bertujuan untuk memberikan gambaran mengenai fakta dan fenomena yang terjadi di Kawasan Cigondewah Kota Bandung. Dengan demikian metode penelitian yang digunakan adalah penelitian deskriftif kualitatif. Penelitian ini ditujukan untuk mendeskripsikan atau menggambarkan fenomena-fenomena yang ada di lapangan seperti bentuk, aktivitas, karakteristik, perubahan, hubungan, kesamaan dan perbedaan fenomena sehingga dalam penelitian ini tidak dilakukan manipulasi hanya menggambarkan sesuai kenyataan atau suatu kondisi eksisting dilokasi.Kata Kunci: Perubahan fungsi lingkungan terbanguan, Perkembangan Koridor, Lingkungan
SUSTAINABLE STREETSCAPE PADA KORIDOR KAWASAN KOMERSIAL Studi Kasus : Koridor Jalan Cibaduyut Raya, Kawasan Sentra Industri Sepatu Cibaduyut (KSISC)
Authors: Ramadhan Try , Wijaya Karto , Muttaqin Zakhi Rezki , Rahmat Amat
Published: July 2018

Abstract:. Cibaduyut Shoe Industry Center (KSISC), especially the corridor of Jalan Cibaduyut Raya is one of shoe shopping center in Bandung. The key to the success of the commercial corridor area to be profitable from the economic aspect is the attractiveness of the space / space of the commercial corridor. Sustainable streetscape plays an important role in shaping the visual image of sustainable cities, as this is one of the most important factors that help the success of cities, and tourist spots. this study aims to see the existing physical quality in the corridor of Jalan Cibaduyut Raya as the center of the activities of shopping area of leather shoes in Bandung. Then examine the elements and principles of sustainable streetscape that can be applied to the corridor of Jalan Cibaduyut Raya so that it impacts on the social, economic and visual image of the city. The method used is qualitative method by focusing on problem solving. The results show that KSISC corridor is not sustainable enough so as to build sustainable streetscape, the principles of sustainable streetscape should be applied thoroughly. Keyword: corridor, sustainable, streetscape Abstrak: Kawasan Sentra Industri Sepatu Cibaduyut (KSISC) khususnya bagian koridor Jalan Cibaduyut Raya merupakan salah satu pusat kegiatan wisata belanja sepatu di Kota Bandung. Kunci kesuksesan kawasan koridor komersial agar menjadi menguntungkan dari aspek ekonomi adalah daya tarik tempat/ruang kawasan koridor komersial tersebut. Sustainable streetscape memainkan peran penting dalam membentuk citra visual kota-kota yang berkelanjutan, karena ini adalah salah satu faktor terpenting yang membantu keberhasilan kota, dan tempat-tempat wisata. penelitian ini bertujuan untuk melihat kualitas fisik existing pada koridor Jalan Cibaduyut Raya sebagai pusat kegiatan area belanja sepatu kulit di Kota Bandung. Lalu mengkaji elemen dan prinsip sustainable streetscape yang nantinya dapat diterapkan pada koridor Jalan Cibaduyut Raya sehingga berdampak pada sosial, ekonomi dan citra visual kota. Metode yang digunakan adalah metode kualitatif dengan berfokus pada pemecahan masalah. Hasil penelitian menunjukkan bahwa koridor KSISC belum cukup berkelanjutan sehingga untuk membangun streetscape yang berkelanjutan, prinsip-prinsip sustainable streetscape harus diterapkan secara menyeluruh. Kata Kunci: koridor, sustainable, streetscape
Response of Some Landrace Rice (Oryza sativa L.) Cultivars to Applied Nitrogen in Lowland Ecosystem
Authors: Mamun M A A , Haque M M , Khaliq Q A , Karim M A , Karim A J M S
Published: July 2018

An experiment was conducted to determine the effects of nitrogen (N) fertilization on growth and yield of some landrace rice (Oryza sativa L.) cultivars in lowland ecosystem. Three popular landrace rice cultivars: Rajashail, Kutiagni and Sadamota were treated with five times of N application viz. (i) two split applications of prilled urea (PU) at 10 days after transplanting (DAT) and before panicle initiation (PI) stage, (ii) deep placement of urea super granule (DPUSG) at 10 DAT, (iii) DPUSG before PI stage, (iv) PU application before PI stage and (v) control. The results showed that the landrace rice cultivar Kutiagni had the highest number of tillers under PU, while  Rajashail gave the highest number of tillers under DPUSG applied before PI stage. Further, Kutiagni produced higher amount of dry matter under two splits of PU, while Rajashail produced higher amount of dry matter under DPUSG applied before PI stage. However, application of PU before PI stage significantly increased leaf area index in all the three landraces. The varieties responded to applied N and produced the highest yield in Kutiagni. The DPUSG at 10 DAT increased straw yield but failed to increase grain yield even over control. The DPUSG before PI stage significantly increased rice yield and economic return. The yield of rice in DPUSG applied before PI stage was comparable to two splits of PU and top dressing of PU before PI stage. Compared to control (2.93 t ha-1), yield increase was 26% in Kutiagni (3.70 t ha-1) under DPUSG before PI stage. These results suggest that Kutiagni was more responsive to added N and this cultivar could be cultivated with DPUSG at PI stage.The Agriculturists 2018; 16(1) 01-12
Comparative Advantages of Lentil (Lens culinaris) and Mustard (Brassica nigra L.) Production and their Profitability in a Selected District of Bangladesh
Authors: Tithi Sabrina Momtaj , Barmon Basanta Kumar
Published: July 2018

The present study was conducted to estimate the profitability, domestic resource cost (DRC) and comparative advantages of lentil and mustard production in Bangladesh. Primary data were used in this study, where a total of 100 randomly selected farm survey (Mustard 50 & Lentil 50) was conducted in Meherpur district using structured questionnaire. The study revealed that per hectare total cost and net profit of lentil production were about Tk. 78,442 and Tk. 86,590, respectively, whereas they were Tk. 62,527 and Tk. 38,718 for mustard production. The benefit cost ratios (BCR) of lentil and mustard production were 2.32 and 1.73, respectively, indicating that both lentil and mustard cultivation in Bangladesh are profitable. The domestic resource costs (DRC) of lentil and mustard production were 0.39 and 0.55, respectively which imply that Bangladesh has comparative advantage in producing both lentil and mustard. The Cobb-Douglas production function coefficients show that farm area, irrigation, pesticides, and chemical fertilizers (Gypsum, MP) were statistically significant factors affecting lentil production having increasing returns to scale. Farm area, irrigation and manure were statistically significant factors affecting mustard production with constant return to scale. In this study, production, technology and marketing problems have been listed down which will help the policy makers and the researchers to undertake proper steps for further improvement of lentil and mustard production in Bangladesh. The Agriculturists 2018; 16(1) 21-33
Effect of Seed Priming on Seed Germination and Seedling Growth of Modern Rice (Oryza sativa L.) Varieties
Authors: Mamun A A , Naher U A , Ali M Y
Published: July 2018

The experiment was carried out in the Seed Laboratory of Bangladesh Agricultural Development Corporation (BADC), Gazipur during June to July 2014 to investigate the effects of different priming methods on seed germination and the seedling growth of some rice (Oryza sativa L.)  varieties. Four rice varieties: 1) Nerica, 2) BRRI dhan51, 3) BRRI dhan41 and 4) BRRI dhan49; and six priming treatments: 1) On-farm Priming, 2) Hardening, 3) Hydro-priming, 4) Osmo-hardening, 5) Vitamin C Priming and 6) Control were used in the experiment. The experiment was laid out in a completely randomized design (CRD). The treatments were replicated three times. The germination percentage and seedling growth parameters differed significantly among the priming treatments. For germination, Nerica variety showed poor performance, whereas the other varieties were found superior. Among the priming treatments, Vitamin C priming and Osmo-hardening were found superior. In case of interaction, germination was increased with Vitamin C priming and Osmo-hardening in Nerica. For seedling growth parameters, particularly vigor index, shoot and root lengths, BRRI dhan41 and BRRI dhan51 were found superior. The priming treatment Vitamin C and Osmo-hardening performed better than others.  Seedling vigor index was increased with Vitamin C priming and Osmo-hardening in Nerica variety. Shoot length at 15th day was influenced by hydro-priming in Nerica. Root length at 10th day was significantly increased with hardening in BRRI dhan41. Vitamin C priming and Osmo-hardening could therefore, be used for improving germination and seedling growth of Nerica. The Agriculturists 2018; 16(1) 34-43
Principes généraux de l’éducation thérapeutique du patient
Authors: Lucet Chloé , Dupouy Julie , Laqueille Xavier
Published: July 2018

L’allongement de l’espérance de vie et le progrès médical ont pour corollaire l’augmentation des maladies chroniques qui constituent un enjeu majeur en termes de santé publique. Responsables de 63% des décès, elles représentent la toute première cause de mortalité dans le monde et sont liées en grande partie à des comportements de santé inadaptés (mauvaise alimentation, sédentarité, addictions…) [1]. Leur expansion a mis en évidence la nécessité de concevoir et de mettre en œuvre une politique de santé publique centrée sur l’éducation du patient. Considéré aujourd’hui comme un acteur de sa propre santé, le patient demande à être informé et impliqué dans le suivi de sa maladie, tout en étant accompagné par des professionnels de santé compétents et à l’écoute de ses besoins.
Éducation thérapeutique et promotion de la santé : contribution du VIH à son émergence en France
Authors: Certain Agnès , Berki Zohra
Published: July 2018

L’actualité est riche en débats dans le domaine de la santé : Lévothyrox®, obligation de 11 vaccins pour les moins de 2 ans, Etats généraux de la bioéthique… La mobilisation des personnes concernées (patients, parents, citoyens), des professionnels de santé et du droit, des scientifiques et des politiques est remarquable. Ces débats sont-ils pour autant des épiphénomènes ou les signes d’une profonde évolution des rôles et des relations des acteurs en présence ? Sont-ils une manifestation de cette démocratie en santé, dont l’instauration est réclamée jusqu’à son inscription dans la loi 1  ? La réponse n’est pas simple. La démocratie est un apprentissage, requérant une information éclairée, des capacités de décision, des choix citoyens : en un mot une éducation dans le champ de la santé.
L’éducation thérapeutique en pédiatrie
Authors: Guilbaud Liliane , Lebras Marie-Noëlle , Baum Sandrine , Couroussé Annabelle , Wanin Stéphanie
Published: July 2018

L’Education thérapeutique du patient (ETP), définie dès 1998 par l’OMS, puis reprise et décrite en France par la HAS en 2007 (1), s’adapte à la pédiatrie, dès lors que les acquisitions des compétences thérapeutiques permettent l’autonomie familiale dans la gestion du traitement de l’enfant, dans un partage évolutif et progressif des compétences de chacun. En pédiatrie, il y a nécessité d’accompagner la famille dans l’adaptation à la maladie et au projet de vie. Cette éducation s’adresse au jeune patient, à sa famille et aux autres acteurs impliqués dans ses soins au quotidien. Elle s’inscrit enfin dans les temps de l’éducation en fonction des temps du patient qui grandit (3). L’ETP fait partie de la prise en charge de la pathologie asthmatique dans les recommandations GINA (5).
Éducation thérapeutique et patients douloureux atteints de cancer : quels enjeux ?
Authors: Renault Tessier Evelyne
Published: July 2018

L’éducation thérapeutique du patient (ETP) s’adresse à des personnes atteintes de maladies chroniques. Selon l’OMS 1 , elle a pour but de leur permettre d’acquérir et de conserver les compétences pour les aider à vivre de manière optimale avec leur maladie. En oncologie, elle se pratique au cours de séances individuelles ou collectives ayant pour objectif, au-delà d’une sensibilisation, l’acquisition de compétences concernant la maladie, ses complications et les traitements prescrits, la compréhension des comportements d’adaptation, ainsi que le fonctionnement du système de soins. Elle permet ainsi que le patient appréhende mieux la maladie et son traitement, améliore ses capacités d’adaptation et d’auto-gestion, coopère en meilleure harmonie avec les soignants, vive plus sainement et maintienne ou améliore sa qualité de vie. Au total, il s’agit qu’il vive mieux sa maladie chronique.
Quel monde voulons-nous pour demain ?
Authors: Beaufils François , Deverre Jean-Claude , Poisson Dominique
Published: July 2018

C’est en 1994 qu’ont été promulguées les premières lois de bioéthique (voir historique des lois page 57). Ces lois se sont inscrites d’emblée dans l’affirmation de principes généraux de protection de la personne humaine qui ont dès lors été introduits dans le Code civil.
Les transformations de l’assurance maladie complémentaire à la lumière de la démutualisation/hybridation des banques coopératives
Authors: Abecassis Philippe , Coutinet Nathalie , Domin Jean-Paul
Published: July 2018

Ce travail analyse l’évolution de deux secteurs comparables : les banques mutualistes et coopératives (M&C) d’une part, les mutuelles de santé et les institutions de prévoyance d’autre part. Si les premières ont entamé une phase de concentration du capital et de démutualisation/hybridation dès les années 1980, les secondes connaissent aujourd’hui une évolution semblable, mais plus prudente. L’article propose dans un premier temps une analyse comparative des deux secteurs et montre dans une seconde partie que les processus d’hybridation constatés dans le secteur bancaire ne sont pas identiques dans l’assurance maladie complémentaire. Les processus de démutualisation/hybridation n’ont pas été sans conséquence sur le fonctionnement des banques M&C, mais il semble que les mutuelles de santé et les institutions de prévoyance protègent mieux leurs principes mutualistes originels.
Les réseaux d’innovation public-privé dans les services (RIPPS) : une nouvelle expression des réseaux d’innovation dans une économie des services et du développement durable
Authors: Djellal Faridah , Gallouj Faïz
Published: July 2018

Le concept de réseau d’innovation est un concept bien établi qui a fait l’objet d’une abondante littérature. Nous nous intéressons dans ce travail à des réseaux d’innovations particuliers, encore peu connus, mais qui se développent dans une économie de service dominante : les réseaux d’innovation public-privé dans les services (RIPPS). Les RIPPS décrivent des collaborations entre organisations de services publiques et privées dans le domaine de l’innovation. Ils diffèrent des RI traditionnels de plusieurs manières. Tout d’abord, les prestataires de services y sont les acteurs principaux. Ensuite, les relations entre les acteurs publics et privés sont placées au centre de l’analyse. Enfin, l’innovation non technologique, souvent négligée dans la littérature, y est prise en compte. L’objet de ce travail est, tout d’abord, d’examiner la manière dont les caractéristiques des RIPPS peuvent contribuer à modifier et enrichir le concept traditionnel de RI, et ensuite, d’en tirer d’éventuels enseignements en matière de politique publique. Ce travail s’appuie à la fois sur un bilan de la littérature et sur l’exploitation d’une base de données d’études de cas de RIPPS constituée dans le cadre du projet européen ServPPIN (Public Private Innovation Networks in Services).
Cumulativité et diversification des exportations dans le bas et le haut de gamme : une vérification empirique
Authors: El Gouddi Sami
Published: July 2018

Notre problématique concerne l’étude de l’aspect cumulatif et la diversification des exportations des pays. Nous tentons de comprendre si la relation entre l’aspect cumulatif et la diversification est stable ou si au contraire elle est, d’une façon ou d’une autre, affectée par la dimension cognitive des pays et des produits. Afin d’apporter des éléments de réponse à ces interrogations, nous menons des estimations économétriques sur des pays à niveaux de développement différents tout en mettant l’accent sur le rôle de la composante cognitive des produits sur la base d’une différenciation qualitative. Ainsi, à travers cette étude empirique, nous chercherons à répondre à trois types de questions. Tout d’abord, dans quelle mesure la spécialisation dans les différentes gammes de qualité peut-elle s’avérer cumulative. La relation entre l’aspect cumulatif et la diversification est-elle vraiment antagoniste, comme le montrent la plupart des modèles théoriques ? Enfin, la différenciation verticale conforte-t-elle les faits statistiques stylisés affirmant l’existence d’une relation positive entre la taille d’un pays et son degré de diversification ? Au-delà des résultats mis en évidence, ce papier ouvre de nouvelles pistes de recherche, notamment en ce qui concerne l’implication des externalités de connaissances dans l’évolution des avantages comparatifs.
Service quality perceptions of campus-based food outlets
Authors: Eresia-Eke Chukuakadibia E. , Stephanou Mon A. , Swanepoel Rochelle
Published: July 2018

Orientation: In a competitive retail business environment, the essence of service quality is invariably amplified. Within a university context, the same applies, given that the student population of customers is relatively finite and yet there are a variety of food outlets on campuses.Research purpose: This study aims to investigate the existence (or lack of it) of a relationship between gender, race and price and the dependent variable of students’ service quality perception of campus-based food outlets. Although gender and race are the most obvious defining demographic features of a student population, the variable of price is usually a major consideration for student purchases.Motivation for the study: The study is an applied research as it is focused on addressing an issue with real-life business implications.Research design, approach and method: It employs the use of data collected in a cross-sectional manner from 200 respondents selected through non-probability sampling.Main findings: The findings of the study indicate that no significant differences exist in service quality perception when gender is considered. Conversely, results show that the service quality perceptions of racial groups differ. The study also finds that a weak but positive correlation exists between price and service quality perceptions.Practical/managerial implications: These results indicate practical implications as they can become useful condiments for refining the offerings and services of the studied campus-based food outlets in the quest to meet or exceed customer expectations.Contribution/value-add: From an academic perspective, the study builds on existing knowledge by exposing the association that the independent variables of gender, race and price have with students’ service quality perception in the specific context of campus-based food outlets in Gauteng, South Africa.
Chief executive officer compensation sensitivity in the South African mining industry
Authors: Bussin Mark
Published: July 2018

Orientation: The level of chief executive officer (CEO) compensation and its relationship with organisational performance has generated considerable interest worldwide. In light of compromised mining productivity as a result of the recent labour unrest in South Africa, some commentators have questioned the justification of certain CEO compensation in the country’s mining industry.Research purpose: The primary purpose of this study was to describe the relationship between CEO compensation and organisational performance in the South African mining industry.Motivation for the study: A deeper understanding of the relationship would enhance knowledge when developing optimal CEO reward systems to ensure sustainability of the mining industry within the South African context.Research design, approach and method: The research was a quantitative, archival study involving 30 mining companies over a 5-year period. The statistical analysis techniques used in the study included analysis of normality variance and multivariate regression.Main findings: The main finding of the research was that there was a moderate to strong relationship between CEO compensation and organisational performance in the South African mining industry. However, operating expenses have progressively increased, putting performance under pressure. Furthermore, it was also found that organisation size plays an influential role in CEO compensation levels.Practical/managerial implications: While the CEO compensation appears to be generally aligned with the organisational performance, the findings suggest that boards of directors should focus on structuring reward systems more optimally to mitigate managerial rent seeking in large companies and unsustainability in smaller companies.Contribution/value-add: This study has contributed to the body of existing knowledge on executive pay for performance in the context of the South African mining industry. In addition, the study has demonstrated that the other measures related to non-performance need to be considered in executive compensation design. The study adds practical value in contributing to information for engagements with stakeholders such as organised labour on executive pay.
‘Flowing’ under the radar in a multifaceted liquid reality: The ekerk narrative
Authors: Joubert Stephan
Published: July 2018

We live in a liquid new world driven by incessant change. Our reality is constantly shaped by new forms of non-linear individualism, which is expressed in countless factions, networks, tribes and alliances. Social systems do not maintain their shape for very long, because they decompose and melt faster than the time it takes to cast them, according to the sociologist Zygmunt Bauman. Religious institutions that do not come to terms with these rapid rates of change soon find themselves trapped in a so-called parallel universe, with hardly any influence on society. In order to embrace our fluid new reality with its numerous open systems and ever-increasing levels of complexity, ekerk understands herself as a movement of Jesus followers whose tribal identity is shaped around his teachings on the Kingdom of God, and which is reflected in the values of relationality and generosity. We have ‘tribal habitats’ in various digital and physical spaces. Under the radar of institutionalised church and academia, but also as their ally in a somewhat subversive manner, ekerk facilitates the spreading of the good news of Jesus in decentralised but very real ways. ekerkalso runs a large generosity ministry, as well as various seminars, meetings and growth programmes such as DieGang/TheGang to invest in young Christian leaders.
Aspects of political theology in the spiritual autobiography of Saint John of Kronstadt (1829–1908)
Authors: Morariu Iuliu-Marius
Published: July 2018

It has been often said nowadays that since the fall of Constantinople, the Eastern-Orthodox Church has not been concerned with political theology. In this research, we will try to show that aspects of the aforementioned topic can be found even in works like the spiritual autobiographies from that space. Therefore, our analysis will focus on the diaries of an important Russian Orthodox priest, Saint John of Kronstadt, who lived in the second half of the 19th century and in the first decade of the 20th century. An important personality of his time, he was a great priest who developed the Eucharistic life, highlighting the relevance of the Holy Liturgy in the Christian life, the social life, offering accommodation, food, money and a place to work for the poor people from his parish and abroad. At the same time, he had a political and intellectual life, being in a good relationship with the tsar and his family, and wrote in his diaries, published during his lifetime and translated into English, his spiritual experiences, his daily life ones and his teaching and opinions on different topics and so on. By highlighting and investigating here episodes like his attitude towards the failed attempt for revolution that took place in Kronstadt in 1905, his relationship with the poor ones and his critique directed to the unfairly attitude of the rich people of his time towards the less fortunate ones or even his preaches against the famous contemporary writer Lev Tolstoy, we will try to show how political theology was understood by such a great father as John of Kronstadt and to emphasise the actuality of some of his ideas related to this topic.
High incidence of cisplatin-induced ototoxicity in paediatric patients in the Western Cape, South Africa
Authors: Phanguphangu Mukovhe , Ramma Lebogang
Published: July 2018

Background: Fourteen million new cancer cases are reported annually, and up to 10% of those involve children below 15 years. Cisplatin, a commonly used anti-cancer drug for its high success rate, is associated with ototoxicity. Cisplatin-induced ototoxicity is characterised by permanent bilateral severe-to-profound hearing loss. Hearing loss, when occurring during childhood, can impact negatively communication development, scholastic performance and quality of life.Aim: To determine the incidence of cisplatin-induced ototoxicity in paediatric oncology.Setting: A retrospective records review of paediatric oncology patients who underwent cisplatin-based chemotherapy and had ototoxicity monitoring from January 2015 to December 2017 at a children’s hospital.Method: Data collected included demographic, cisplatin treatment and audiometric information. The data were analysed using descriptive and inferential statistics.Results: A total of 49 records meeting the inclusion criteria were reviewed. Ototoxic hearing loss was found in 39 (80%) of the patients whose records were reviewed and the majority (56%) presented with a bilateral moderate-to-severe sensorineural hearing loss. Distortion product otoacoustic emissions were absent in 32 (67%) patients. Cumulative dose (> 200 mg/m2) was associated with higher incidences of ototoxicity (odds ratio [OR]: 1.81; 95% confidence interval [CI]: 0.67–17.34; p = 0.044). Younger patients (< 10 years) had higher odds of developing ototoxicity, but this was not statistically significant (OR: 4.00; 95% CI: 0.82–19.46; p = 0.085).Conclusion: This study found a high incidence of cisplatin-induced ototoxicity in paediatric oncology patients. This is concerning because hearing loss during this age can have long-term negative impact on a child’s development and overall quality of life. Early identification of ototoxicity-induced hearing loss and appropriate intervention are highly recommended in this patient group.
Metachronous endobronchial metastasis from uterine cervical adenocarcinoma
Authors: Darling Harry S.
Published: July 2018

Malignant involvement of the lung can be primary or metastatic. Although primary lung cancer may be endobronchial, parenchymal or both, metastases to the lung are generally parenchymal. However, less commonly, they may be endobronchial. The lungs are the most common site of metastases among all the malignancies. Common extrapulmonary malignancies causing endobronchial metastases (EBMs) are breast, colorectal and kidney. EBMs from uterine cervical cancer are very rare. Although there are a few case reports in the medical literature describing EBM from cervical cancer, none are from adenocarcinoma histology. In this study, we report a case of EBM which on histopathological examination and immunohistochemistry were found to be from a prior adenocarcinoma cervix. Differentiating EBM from bronchogenic carcinoma and other more common extrapulmonary solid organ malignancies may present a clinico-pathological and radiological challenge.
EVALUACIÓN DE LAS CARACTERÍSTICAS DINÁMICAS Y SERVICIABILIDAD VIBRATORIA DE ENTREPISOS DE MADERA
Authors: Toledo Mario , Nallim Liz , Sanchez Ezequiel Domingo
Published: July 2018

Los sistemas de entrepisos de madera son comunes en edificios públicos y privados en la ciudad de Salta, Argentina. Las vibraciones verticales pueden provocar una sensación de incomodidad que afecta la serviciabilidad estructural. Recientemente, se aprobó el nuevo Reglamento Argentino de Estructuras de Madera CIRSOC 601 que contempla el control de vibraciones, que establece un valor mínimo para la frecuencia natural de vibración y limita la deflexión máxima instantánea. Por lo mencionado, la determinación de las características dinámicas es de fundamental importancia para la verificación y estudio de la serviciabilidad vibratoria de este tipo de sistemas estructurales. En este trabajo se estudia la serviciabilidad vibratoria de entrepisos de madera estableciendo comparaciones con los criterios propuestos por la normativa vigente. Se presentan resultados obtenidos experimentalmente y aplicando métodos numéricos, a través del método de los elementos finitos (MEF), de entrepisos de madera construidos con Pino Elliottis, considerando diferentes combinaciones de luces. En cuanto a la determinación experimental, se obtuvieron las características dinámicas utilizando acelerómetros triaxiales Kinemetrics y registradora de datos. En cuanto al MEF, se construyeron modelos tridimensionales empleando el programa SAP. Del análisis de los resultados obtenidos tanto numérica como experimentalmente, y de la comparación con los criterios propuestos por el reglamento CIRSOC 601, se extraen conclusiones acerca de la serviciabilidad de esta tipología de entrepisos.
USO DE ARMADURA INCORPORADA NO ANSYS CUSTOMIZADO PARA A ANÁLISE DE VIGAS EM CONCRETO ARMADO
Authors: Manica Lazzari Paula , Campos Filho Américo , Manica Lazzari Bruna , Rodrigues Pacheco Alexandre
Published: July 2018

Este trabalho versa sobre o desenvolvimento de um modelo computacional, através do método dos elementos finitos, para análise não linear de estruturas em concreto armado sob estados planos de tensão com a utilização de armadura incorporada no ANSYS. O objetivo deste trabalho foi implementar dois procedimentos distintos no modelo computacional, baseados em um modelo elasto-viscoplástico. No primeiro, a resposta da estrutura é dada para um carregamento instantâneo, considerando o material com um comportamento elastoplástico. No segundo, a resposta da estrutura é dada ao longo do tempo, considerando, neste caso, que o material possui um comportamento viscoelástico. Para a representação do modelo constitutivo do concreto e da armadura, utilizou-se a ferramenta de customização UPF (User Programmable Features) do ANSYS, onde foram adicionadas ao programa principal as novas sub-rotinas desenvolvidas em linguagem FORTRAN. A grande vantagem da implementação deste modelo foi a possibilidade da utilização de elementos bidimensionais quadráticos de 8 nós e 2 graus de liberdade por nó (PLANE183) com armadura incorporada (REINF263), de modo a reduzir o esforço computacional e tornar a solução do problema muito mais rápida e eficaz. A fim de validar as sub-rotinas implementadas através da interface com o programa principal, foram simuladas as vigas de concreto armado, ensaiadas por Bresler e Scordelis (1963), que abrangem uma grande variedade de comportamentos, incluindo situações de falhas por flexão e corte. A comparação entre análises numéricas e experimentais mostraram resultados bastante satisfatórios.