bluuebunny/crossref_metadata_2025 huggingface dataset:
Distribution of macronutrients (N, P, K, Mg) from single-nutrient and compound fertilizers application in oil palm seedlings (Elaeis guineensis Jacq.)
Authors: Ginting Eko Noviandi , Rahutomo Suroso , Farrasati Rana , Pradiko Iput
Published: April 2021

Nutrients availability and plant's ability to absorb nutrients are essential factors in supporting plant performance. There are two forms of fertilizer as a source of nutrients for oil palm, which are single-nutrient fertilizer (SNF) and briquette compound-nutrient fertilizer (BCNF). This study observed the concentration, uptake, distribution, and efficiency of macronutrients in plant organs of oil palm seedlings with two different fertilizer types. An experiment using oil palm seedlings was arranged in non-factorial complete randomized design (CRD) with three treatments, namely control, NPK in the form of briquettes, and single nutrient fertilizer consisting of urea, TSP, MOP, and kieserite with doses adjusting the composition of the slow-release BCNF (16-10-24-0.75) in three replications with a total of 27 seedlings. The results showed that the concentration, uptake, and distribution of nutrients between treatments and control were not significantly different. The order of nutrient uptake in leaves and stems of plants was N > K > Mg and P, while in roots was K > N > Mg > P. In BCNF and SNF treatments, the biomass accumulation in the stems, roots, and leaves were at percentage of 41 %, 30 %, and 29 %, while in the control, the biomass accumulation in the roots, stems, and leaves were at percentage of 39 %, 33 %, and 28 %, respectively. BCNF treatment had a greater efficiency indicated by a higher nutrient use efficiency (NUE) value compared to SNF or control.
Relationship between Nonspecific Low Back Pain and Physical Function among Japanese High School Long-distance Runners
Authors: Nakagawa K. , Mitomo A. , Takahashi Y.
Published: April 2021

Background: For long-distance runners, low back pain as well as lower extremity disorders are becoming more common. This study analyzed the relationship between regular physical assessment results and nonspecific low back pain among long-distance runners. Methods: Subjects included 105 high school long-distance runners, who were divided into the low back pain group (n = 20; LP) and non-pain group (n = 85; NP). All subjects underwent regular chronic pain and physical assessments every six months. Differences in each measurement between both groups were analyzed using an unpaired t-test for comparison.Results: The LP had a shorter history of athletics (LP=3.2 years, NP=4.6 years, 95% confidence interval (95%CI): -2.55, -0.28, r=0.45), a greater hip extension angle (LP=32.7°, NP=28.4°, 95% CI: 2.85, 5.61, r=0.67), a lower hip extension muscle strength (LP=3.1 kgf/kg, NP=4.0 kgf/kg, 95% CI; 0.19, 0.61, r=0.45), and a greater number of times during the stand-up test (LP=11.1, NP=8.1, 95% CI; 0.40, 5.56, r=0.45) than the NP.Conclusion: An excessive hip extension angle and insufficient hip extension muscle strength were considered as risk factors. It is possible that the excessive movement of the hip joint and the biarticular muscles may have caused the low back pain in the inexperienced runners.
ANTIOXIDANT ACTIVITY OF METHANOL EXTRACT NATUNA MARINE SPONGE (PORIFERA) WITH DPPH METHODE
Authors: MAYEFIS DELLADARI , HAINIL SRI , WIDIASTUTI SISKA
Published: April 2021

Objective: Natuna sponge is a marine animal that contains a wide range of secondary metabolites that can be utilized in the field of pharmacy. The research aims to test the phytochemical content and antioxidant activity of the Natuna methanol marine sponge extract. Sample extraction is done by the maceration method with methanol solvent.

Methods: Phytochemical tests include alkaloid testing, flavonoids, steroids, saponins, and tannins. Test antioxidant activity using the immersion DPPH method (1.1-diphenyl-2-picryl hydroxyl) measured absorption at a wavelength of 517 nm.

Results: The phytochemical test results showing the sponge of Natuna contain secondary metabolites including alkaloids, flavonoids, steroids, saponins, and tannins.

Conclusion: This Natuna sponge methanol extract has an antioxidant activity that is very strong with an IC50 value of 52.91 ppm, and the comparator used is Vitamin C with an IC50 value of 43,51 ppm.
COMMUNITY-BASED STUDY ON PREVALENCE AND PATTERN OF SELF-MEDICATION PRACTICES AND ITS ASSOCIATED FACTORS IN S.S LAYOUT, DAVANGERE
Authors: FATHIMA NAZISH , JACOB ANITTA MARIAM , VARUGHESE ANJU , ABRAHAM ARPITHA , MATHEW ASHA
Published: April 2021

Objectives: Self-medication practice is an element of self-care and it is the use of medication without the prescription of health-care professionals. This community-based prospective observational study was undertaken with the aim to evaluate the prevalence and pattern of self-medication practices and to assess the knowledge, attitude, and belief of the subjects toward this practice.

Methods: This study was carried out in S.S Layout, Davangere, for a period of 6 months. The data were collected in predesigned validated questionnaire. A total of 400 subjects were participated in the study.

Results: Among 400 individuals, 280 subjects were practicing self-medication, and this practices were high among females 174 (62%) than males 106 (38%). The majority of subjects participated in this study were students (36%). The most common indications for self-medication practice were headache (30%) followed by fever (25%) and heartburn (13%). The highly used drug in this practice was acetaminophen (57%). The most commonly used category of drugs for self-medication were analgesics (57%) followed by antacids (17%) and others (anti-hypertensive, anti-diarrheal, anti-pyretic, anti-histamines, and laxative) (13%). The main reasons for self-medication practice were no need to visit the doctor for minor illness (62%), long distance to health center (24%), and inability to pay for health-care cost (6%).

Conclusion: This study shows that self-medication is widely practiced among students in our society. There is dire need to make them aware about the pros and cons of self-medication in order to ensure safe usage of drugs. Interventions are required to reduce the frequency of misuse of drugs.
DEVELOPMENT AND VALIDATION OF AN RP-HPLC METHOD FOR THE DETERMINATION OF ULIPRISTAL ACETATE IN BULK AND PHARMACEUTICAL DOSAGE FORM
Authors: SINGHA S SANATHOIBA , RAO T SREENIVAS
Published: April 2021

Objective: This work makes an attempt to establish a sensitive and accurate method for the development and validation of an analytical method for estimation of ulipristal acetate (UPA) in bulk and pharmaceutical dosage form.

Methods: A mixture of 20 mM acetate buffer pH 3.7 and methanol in the ratio of 70:30 (v/v %) was used as the mobile phase. An xBridge™ C18 column (250 mm × 4.6 mm, 5μ) was used for the analysis at a flow rate of 1 ml/min, injection volume of 20 μl, run time of 15 min, and detection wavelength of 309 nm. The repeatability (within-day in triplicates) and intermediate precision (for 2 days) were carried out by six injections and the obtained results within and between the days of trials were expressed as percent relative standard deviation (% RSD). The linearity of the method was determined by the analysis of analyte concentration across a range of 10 μg/ml–60 μg/ml.

Results: The % RSD values of precision studies were found to be below the accepted limit of 2%. The method was found to be linear with a correlation coefficient (R2) of 0.98. The method was also found to be accurate and robust with suitable values. Limit of detection (LOD) and limit of quantification (LOQ) of the method were found to be 0.371 μg/ml and 1.23 μg/ml, respectively.

Conclusion: The results of analysis prove that this method can be used for the routine determination of UPA in bulk drug and in pharmaceutical dosage forms.
EVALUATION OF THE ANALGESIC ACTIVITY OF AQUEOUS AND ALCOHOLIC EXTRACT OF FLOWERS OF PLUMERIA ALBA LINN IN EXPERIMENTAL ANIMALS
Authors: VINOTHA AT SATHIYA , MS UMAMAGESWARI , A UMAMAHESWARI , S VELARUL
Published: April 2021

Objective: Plumeria alba (Apocynaceae), commonly known as “Frangipani” is an important medicinal plant, widely distributed throughout Southern India. In the traditional medicinal system, different parts of this plant have been mentioned to be useful in a wide variety of diseases. In this study, analgesic activity of aqueous and alcoholic extract of flowers of P. alba Linn was evaluated by hot-plate and acetic acid-induced writhing methods to substantiate and expand its clinical applications.

Methods: The flowers of P. alba were collected from the local area in and around Coimbatore (India). The flowers were dried, powdered, and were extracted using soxhlet apparatus for 12 h using water and 95% of ethanol as a solvent. The test extracts were administered orally at a dose of 100 & 200 mg/kg while diclofenac sodium (10 mg/kg) served as standard.

Results: The ethanolic flower extract of 200 mg/kg had significant analgesic activity in acetic acid-induced abdominal writhing response (***p<0.001) when compared to control and standard drug diclofenac. It also exhibited significant analgesic activity (***p<0.001) by increasing the pain reaction time of the rats in comparison to control and standard in hot plate method.

Conclusion: The results suggest that ethanolic flower extracts of P. alba possess potent analgesic properties, which support its use in traditional medicine and suggesting that the plant should be further investigated for its pharmacological active natural products.
CLINICAL PROFILE, PRESCRIPTION PATTERNS, AND ADVERSE DRUG REACTIONS IN PATIENTS WITH VITILIGO: A PROSPECTIVE STUDY
Authors: M INDRANEEL , M GOVARDHAN , T KIRANMAYI , PR SNEHA REDDY , A SUREKHA , REKHA O DIVYA , SHARAN T RAM , BALAJI ANNA
Published: April 2021

Objectives: The objectives of the study were to assess clinical profile (age of onset, age of presentation, gender, site of involvement, severity (stage), type of vitiligo, triggering factors, and associated diseases), prescription patterns (monotherapy, combination therapy, oral, topical, and therapeutic categories of drugs prescribed) and to monitor and report adverse drug reactions (based on World Health Organization [WHO] causality assessment scale) in vitiligo patients.

Methods: A hospital-based prospective observational study was carried out by evaluating and assessing the clinical profile and prescription patterns of 85 patients who attended dermatology venereology and leprosy (DVL) outpatient department at Sri Padmavathi Medical College for Women, SVIMS, Tirupati, over a period of 6 months from June 2019 to December 2019.

Results: In our study, forty four (51.77%) patients were female, vitiligo vulgaris is the most common morphological type observed in twenty seven (31.76%) patients. 31–50 years was the predominant age group. The mean age of onset and presentation was 38.35 (standard deviation of 18.37) and 43.27 (standard deviation of 17.96) years, respectively. Forty-one (48.23%) patients were having Stage 1 vitiligo. Fifty (58.85%) patients were having vitiligo at more than 1 site. Twelve (14.11%) patients were having a positive family history of vitiligo. Thirty-seven (43.53%) patients had triggering factors. Associated diseases were found in thirty (35%) patients. Combination therapy was given to sixty one (71.77%) patients. Topical medications were given to fifty two (61.18%) patients. During the study, we did not have a single patient complaining of any adverse drug reaction.

Conclusion: Longer the time after appearance of vitiligo, lesser the number of patients attending follow-up. If vitiligo is diagnosed at the earliest stage, more are the chances for complete repigmentation. Patients with a poor economic background are less bothered about their skin condition and are not using medications properly.
RECURRENT MALIGNANT APOCRINE SWEAT GLAND CARCINOMA - A CASE REPORT
Authors: JANGA AKHILA , ZIAUDDIN MOHAMMED , PATLOLLA RAVI CHANDER
Published: April 2021

Apocrine carcinomas arise from normal or modified sweat glands. The slow-growing nature and rarity of sweat gland carcinomas complicate their diagnosis at the early stage. The incidence of PASGC is quite low at 0.0049–0.0173 cases/100,000 persons/year. A 21-year-old male patient was presented in February 2016 with small solitary mass in the right axilla with mild tenderness and pain. Underwent wide local excision and axillary dissection at our institution followed by adjuvant radio and chemotherapy. Later on, after 18 months developed local recurrence and was planned for re-surgery and a second phase of palliative radiotherapy. After a year, presented to the hospital with pin sized irregular swelling in the axilla. Sweat gland carcinomas which are rarely diagnosed create a pathological dilemma due to their unpredicted biological behavior. However, wide local excision with or without nodal dissection is the primary treatment till date. In this particular case even though patient had underwent axillary node dissection, patient had recurrence twice with no distant metastasis which is a key point to be noted. Thorough study of the available apocrine carcinoma case reports or case series, the better knowledge regarding the apocrine carcinoma can be obtained.
HIGH-PERFORMANCE LIQUID CHROMATOGRAPHIC ESTIMATION METHOD FOR TRANSDERMAL DIFFUSION STUDY OF GRANISETRON
Authors: BUKKA RAMA , HN CHAYA
Published: April 2021

Objective: The study is aimed to develop a simple, isocratic and sensitive reversed-phase high-performance liquid chromatography method for the analysis of granisetron during transdermal permeation studies through porcine ear epithelium.

Methods: A reversed-phase (C18) column was used with ultraviolet detection at 210 nm. Selected mobile phase contained 25% (v/v) of acetonitrile and 75% (v/v) of 0.25 mM potassium dihydrogen orthophosphate solution pH adjusted to 3.0 using 1% orthophosphoric acid solution.

Results: Calibration curve showed good linearity over 0.1–30 μg/mL concentration range of porcine ear permeates in 80% ethanol and 20% water (blank permeates). The applicability of the method was demonstrated by the analysis of diffusion study samples of granisetron through porcine ear epithelium and the steady-state permeability flux (J) from ethanolic solution was found to be 4.707 µg/square cm/h.

Conclusion: The developed method can be used in the analysis of diffusion study samples of granisetron transdermal formulations through the porcine ear epithelium.
A REVIEW ON NANOEMULSIONS: FORMULATION, COMPOSITION, AND APPLICATIONS
Authors: HAMID KHAN MOHAMMAD , WAIS MOHAMMAD , SAWANT GAURANG
Published: April 2021

Nanoemulsions are sub-micron sized emulsions that are undergoing detailed assessment as potential drug carriers for enhancing the delivery of therapeutic agents. These are to date the most developed nanoparticulate systems for the systemic delivery of active pharmaceutical for controlled drug delivery as well as targeting. These are the thermodynamically durable isotropic system, in which two incompatible liquids (water and oil) are blended to form a single homogenous phase by utilizing a required quantity of surfactants to achieve mixing with a droplet diameter approaching roughly in the range of 0.5–100 μm. They find applications in various fields such as cosmetics as well as are adopted in various routes of administration.
SYNTHESIS, IN SILICO CHARACTERIZATION AND EX VIVO EVALUATION OF THE NOVEL ORGANIC NITRATE NDIBP AS A POTENTIAL VASORELAXANT AGENT
Authors: MEDEIROS CAVALCANTI AIRLLA LAANA DE , LINS ROCHA PATRÍCIA KEYTTH , LUNA ISADORA SILVA , BRANDÃO MARIA CLÁUDIA RODRIGUES , DA TRINDADE EMMELY OLIVEIRA , GUIMARÃES GEOVANI PEREIRA , ATHAYDE-FILHO PETRÔNIO FILGUEIRAS , MURATOV EUGENE , KHAN BARKAT , TULLIUS SCOTTI MARCUS , ANDRADE BRAGA VALDIR DE
Published: April 2021

Objective: This study aimed to describe the synthesis and biological/pharmacokinetic potential of the 1,3-diisobutoxypropan-2-yl nitrate (NDIBP) using in silico and ex vivo approaches.

Methods: The compound was characterized by Fourier-transform infrared spectroscopy and 1H and 13C- nuclear magnetic resonance spectra. NDIBP biological activity spectrum was obtained by Prediction of Activity Spectra for Substances (PASS). The pharmacological effect was validated in ex vivo studies using mesenteric artery. Drug-like properties and Absorption Distribution Metabolism Excretion and Toxicity (ADMET) studies were carried out by pkCSM (Predicting Small-Molecule Pharmacokinetic Properties Using Graph-Based Signatures) software.

Results: PASS prediction indicated NDIBP as nitric oxide (NO) donor with vasodilator effect. Ex vivo studies validated PASS analysis and showed the NDIBP vasorelaxant activity in mesenteric arteries. Physicochemical parameters and ADMET prediction suggested that NDIBP is a drug-like molecule with a good theoretical oral bioavailability, good absorption in the gastrointestinal tract, and a low distribution in the tissues.

Conclusion: All the data indicated that NDIBP possesses biological activities and drug-like properties to be considered as a vasorelaxant agent and a good candidate for further investigation in the treatment of arterial hypertension and drug development studies.
On comparative Proto-Mǐn *Dʰ- and putting conjectural morphology in its place
Authors: Smith Jonathan
Published: April 2021

Recent conjectural morphological (‘word family’) approaches to early Chinese assign the aspirated causative verbs of the Mǐn group to Jerry Norman’s comparatively reconstructed Proto-Mǐn voiced aspirated *Dʰ-, proposing on this basis that *Dʰ- reflects prefixation of Old Chinese provenance. In this article, I argue that comparative phonological work on Mǐn has never suggested *Dʰ- for these items. In this case as elsewhere, morphological models can be of use but require grounding in comparative results.
EFEKTIVITAS PENGELOLAAN ALOKASI DANA DESA PADA PEMERINTAH DESA DI KOTA BATU
Authors: Sari Shenia Nilla , Abdullah M Faisal
Published: April 2021

The purpose of this research is to find out the effectiveness of the management of village fund allocation in the Village Government in Batu City and to find out the opportunities and challenges faced in managing ADD. Data analysis used in this study is to use the effectiveness measurement ratio in accordance with the effectiveness criteria and use the SWOT analysis. The results of this study indicate the effectiveness of the management of village fund allocations in 19 villages in Batu City in 2017-2018 already in effective criteria. Opportunities faced in ADD management are the role of the role of the city government, the sub-district government and village facilitators, the synergy between the city and village governments, the information system, the increasing welfare of the community and the economy and improving village infrastructure facilities and infrastructure. The challenges faced in the management of ADD are the uncertainty of the ADD disbursement process, the reduced budget from the city government, the success rate of the program that is not according to plan and the delay in regulation regarding village financial management.Keywords : ADD, Effectiveness village funds allocation, SWOT analysis
PENGARUH INFRASTRUKTUR PEMBANGUNAN TERHADAP PERTUMBUHAN EKONOMI JAWA TIMUR
Authors: Panama Herlina , Zuhroh Idah , Nuraini Ida
Published: April 2021

This study aims to determine the effect of Infrastructure for Road, Electricity, Water, Education, and Health Development on the economic growth of the study of the North-South Corridor of East Java Province in 2010-2017. The data used in this study is to use secondary data taken from 2010-2017. This study uses a multiple linear regression tool using panel data method by testing hypotheses such as F test, t test, and Determination Coefficient R2. Based on the results of the study, it shows that Water, Electricity and Education Development Infrastructure has an effect on economic growth in the North-South Corridor Area of East Java while Road and Health Infrastructure does not affect Economic Growth in the North Corridor- South East Java Province. Water infrastructure has a positive and significant effect on economic growth. Electricity infrastructure has a positive and significant effect on economic growth. Educational infrastructure has a positive and significant effect on economic growth. Health Infrastructure has a negative and significant effect on economic growth. Based on the results of this study, it is necessary to have policies that can encourage infrastructure to help increase economic growth.
Kearifan Lokal Kabumi: Media Internalisasi Nilai-Nilai Karakter Masyarakat Tuban Jawa Timur
Authors: Widianto Ahmad Arif , Lutfiana Rose Fitria
Published: April 2021

Kearifan lokal berperan penting dalam kehidupan masyarakat, utamanya di tengah gencarnya arus modernisasi. Hal ini berdampak terhadap perubahan sosial di masyarakat. Kabumi sebagai salah satu kearifan lokal menjadi media penting bagi internalisasi nilai-nilai karakter masyarakat. Penelitian ini bertujuan untuk mendeskripsikan kearifan lokal kabumi sebagai media internalisasi pendidikan karakter bagi masyarakat di Desa Bader, Kecamatan Jatirogo, Kabupaten Tuban. Metode penelitian yang digunakan adalah kualitatif deskriptif. Penelitian dilakukan di Desa Bader, Kecamatan Jatirogo, Kabupaten Tuban. Subjek penelitian ini adalah kepala desa, sesepuh desa, dan masyarakat Desa Bader. Pengumpulan data dilakukan dengan wawancara, observasi, dan studi dokumentasi. Teknik analisis data menggunakan model Miles dan Hubberman. Uji keabsahan data menggunakan triangulasi sumber. Hasil penelitian menunjukkan bahwa proses internalisasi nilai-nilai karakter dilakukan melalui lima tahapan, yaitu penerimaan nilai, respon, seleksi nilai, internalisasi, dan aktualisasi. Di sisi lain, nilai-nilai karakter yang muncul sebagai bentuk internalisasi kearifan lokal kabumi antara lain nilai religius, gotong royong, toleransi, dan peduli lingkungan.
 
Local wisdom plays an important role in people's lives, especially in the midst of modernization. This phenomenon has an impact on social change in society. Kabumi as one of the local wisdoms is an important medium for internalizing character values ​​in society. This study aims to describe the local wisdom of Kabumi as a medium for internalizing character education for the community in Bader Village, Jatirogo District, Tuban Regency. The research method used is descriptive qualitative. This research was conducted in Bader village, Jatirogo district, Tuban district. The subjects in this study were the village head, village elders and the Bader village community. Data collection was carried out by interview, observation, and documentation. The data analysis technique used the Miles and Hubberman technique. The data validity test used source triangulation. The results showed that the process of internalizing character values ​​was carried out in five stages, namely acceptance of value, providing response, value selection, internalization and actualization. On the other hand, the character values that appear as a form of internalization through local Kabumi wisdom include religious values, mutual cooperation, tolerance, and environmental care.
DEPOIMENTOS SOCIAIS SOBRE O USO DE PLANTAS MEDICINAIS NO TRATAMENTO DA DOR
Authors: Machado Sara Tavares de Sousa , Batista Paulo Ricardo , Sousa Jéssica Pereira de , Rosa Andressa Gabrielli da Silva , Santos Ana Deyva Ferreira dos , Kerntopf Marta Regina
Published: April 2021

Almejamos investigar o saber popular do uso de plantas medicinais associados ao manejo da dor e verificar a interação deste conhecimento com os aspectos da biomedicina local, centrando-se nesta temática ainda desafiadora apresenta contribuições interdisciplinares em especial para díade ciências da saúde/ciências sociais e humanas. Foram entrevistados moradores da comunidade Santo Antônio, Barbalha, Ceará. Os informantes apresentam nível de instrução escolar baixo e a agricultura como principal fonte de renda. Os resultados obtidos denotam que os entrevistados externaram a preferência pela medicina caseira de plantas no manejo de algias. Percebeu-se que o diálogo com os profissionais a respeito da fitoterapia é desfavorecido, e aos que possuem essa interlocução, predomina a não indicação. Assim, aponta-se para a necessidade de aceitação, incorporação e intervenção adequadas no que concerne essas tradições culturais milenares na expectativa de um atendimento integrado de atenção primária.
Combat COVID-19 with Exercise and Vitamin D Supplementation
Authors: Mishra Allan , Murrell William D
Published: April 2021

COVID-19 is a raging pandemic with cases, hospitalizations and deaths surging. Prevention has focused to date on mask wearing, social distancing, and the development of vaccines. Novel mitigation strategies, however, are needed to combat the pandemic optimally.There was an epidemic of inactivity in 2020 partially because of government recommendations to stay indoors and the mandated closure of gyms. Vitamin D deficiency is also a common worldwide problem, especially for persons of color. These two issues are contributing to the severity of the pandemic and should be addressed.
Simultaneous Estimation of Drug Digoxin in Tablet Dosage Form by UV Spectrophotometric Method
Authors: Paulzagade Omita , Borkar Anshuman
Published: April 2021

Digoxin has a cardiac glycoside property. Aim of the present study was to develop UV - Spectrophotometric method using simultaneous equation for the drug Digoxin in tablet formulation. Objective of the study is to develop a simple and precise analytical method for the drug Digoxinwith statistical data. In validation, our study includes accuracy, precision, specificity, limit of detection, limit of quantitation, linearity and range parameters. Digoxin has antihypertensive activity and various new tablet formulations were already introduced in the market, so we compared the results of marketed tablet formulation with standard drug Digoxin. Literature review helped us in planning of work that includes selection of solvent, wavelength identification, sample preparation, analyzing test & standard solutions and validation study. The detection of the drug was carried out in 220 nm. The method was linear (Correlation Coefficient= 0.99) over the range of 25 to 125 μg/ml, precise (Standard Deviation = 0-1, Relative Standard Deviation < 2%), accurate (mean recoveries from 97.5% and 104.3%), and had a LOD and LOQ equal to 0.12 and 0.38 μg/ml, respectively. For specific stability, the forced degradation study (alkali, acid, oxide and heat) was performed on marketed formulations to show the stability indicating ability of the developed method. The method showed robustness, remaining unaffected by deliberated variations in spectrophotometric conditions. Due to correlative results the validated analytical method was successfully applied for the quantification of Digoxin and demonstrated the uniform distribution of the drug into the systems. Finally, we developed an accurate, less time consuming and cheaper UV-Spectrophotometric method for the determination of the Digoxin in tablet formulation
Pengaruh Peran Modal Sosial Terhadap Loyalitas Anggota Kelompok Tani Alpukat Ngudi Rahayu 2 Kecamatan Jambu Kabupaten Semarang
Authors: Sinaga Herlin Yolanda , Gayatri Siwi , Satmoko Sriroso
Published: April 2021

Terdapat beberapa faktor yang berpengaruh terhadap loyalitas anggota terhadap kelompok tani yaitu Kepercayaan, Kerjasama dan nilai/norma yang tergolong dalam modal sosial. Penelitian ini bertujuan untuk menganalisis peranan modal sosial yang ada di kelompoktani, menganalisis tingkat loyalitas anggota kelompoktani dan menganalisis bagaimana peran modal sosial terhadap loyalitas anggota kelompoktani. Metode penelitian yang digunakan adalah survey. Sampel penelitian adalah anggota kelompoktani Ngudi Rahayu 2, Dusun Kalibening, Desa Kebondalem, Kecamatan Jambu, Kabupaten Semarang. Analisis yang digunakan dalam penelitian ini adalah analisis deskriptif dan analisis regresi berganda. Hasil penelitian menunjukkan bahwa tingkat loyalitas anggota kelompoktani tergolong tinggi (100%), kepercayaan anggota tergolong tinggi (100%), kerjasama anggota tergolong tinggi (100%) dan nilai/norma anggota tergolong tinggi (83,3%). Hasil penelitian menunjukkan bahwa modal sosial yang terdiri dari kepercayaan, kerjasama dan nilai/norma berpengaruh secara nyata terhadap tingkat loyalitas anggota kelompok tani Ngudi Rahayu 2 di Kecamatan Jambu Kabupaten Semarang dengan total pengaruh sebesar 78,8% sedangkan 21,2% lainnya dipengaruhi oleh variabel lain yang tidak dimasukkan kedalam model dalam penelitian.
Analisis Sikap Konsumen Terhadap Pembelian Beras Organik Melalui E-Commerce di Kota Semarang (Studi Kasus pada Konsumen Beras Organik Eka Farm Produksi CV Agro Sukses Abadi)
Authors: Larasati Dewi , Prasetyo Edy , Santoso Siswanto Imam
Published: April 2021

Penelitian ini bertujuan untuk menganalisis sikap konsumen terhadap atribut beras organik Eka Farm dan faktor-faktor yang mempengaruhi keputusan pembelian beras organik yang dipasarkan melalui sistem E-Commerce di Kota Semarang. Penelitian dilaksanakan pada bulan Februari sampai bulan April 2020. Metode penelitian yang digunakan adalah survei. Metode penentuan sampel yang digunakan yaitu dengan accidental sampling. Jumlah sampel ditentukan secara quota sampling sebanyak 100 responden yang dipilih secara purposive sampling. Pengumpulan data dilaksanakan dengan menggunakan kuesioner secara online. Analisis data yang digunakan adalah analisis multiatribut fishbein dan analisis statistik yaitu regresi linier berganda. Hasil penelitian menunjukkan bahwa nilai kepercayaan yaitu kemasan 4.34, varian 4.29, warna 4.15, dan harga 3.72. Nilai kepentingan yaitu harga 4.22, varian 4.2, kemasan 4.19 dan warna 4.17. Sikap total konsumen sebesar 69.2065 yang berarti netral. Faktor varian, kemasan, warna dan harga berpengaruh secara signifikan terhadap keputusan pembelian konsumen.
El desarrollo sostenible como política en Colombia
Authors: Vargas-Chaves Iván , Gómez-Rey Andrés , Rodríguez Gloria Amparo
Published: April 2021

El presente artículo pretende mostrar cómo la existencia del principio de desarrollo sostenible en el ordenamiento jurídico, posee un impacto sobre el bienestar de las personas; relación que además puede considerarse en tensión en aquellos casos donde se presenten prohibiciones absolutas que impidan un verdadero desarrollo sostenible en sus tres dimensiones: social, económica y ambiental. Para mostrar esta realidad, se llevó a cabo un análisis normativo, jurisprudencial y doctrinal, con énfasis especial en el caso de los ecosistemas de páramo, donde, en pro del proteccionismo ambiental, se han creado restricciones absolutas en relación al uso de los recursos naturales renovables, soportado en la bandera del interés general. Como resultados, los autores logran evidenciar las tensiones que plantea el principio de desarrollo sostenible respecto a derechos por cuenta de su incorrecta aplicación e interpretación.
Maltrato en relaciones de noviazgo de jóvenes universitarios en Bucaramanga y su área metropolitana
Authors: Redondo-Pacheco Jesús , Durán-Cubides Laura Viviana , Luzardo-Briceño Marianela , Inglés-Saura Candido José
Published: April 2021

El maltrato en las relaciones de pareja supone una forma de actuar agresiva y negativa que tiene como fin causar daño en la pareja, y puede presentarse desde múltiples dimensiones (maltrato físico, psicológico, emocional, sexual y económico). El objetivo principal fue caracterizar las experiencias de maltrato presentes en las relaciones de noviazgo de jóvenes universitarios en Bucaramanga y su área metropolitana en una muestra de 407 estudiantes universitarios, vinculados a 26 carreras profesionales en 7 universidades públicas y privadas de la ciudad (62.9% mujeres y 37.1% hombres), con edades comprendidas entre 18 y 30 años. El 91.6% informó haber vivenciado, al menos una vez, alguna de las tipologías de maltrato por parte de su pareja, evidenciando que es más frecuente en las mujeres; sin embargo, no se encontró una diferencia estadísticamente significativa en cuanto al género, exceptuando el maltrato físico. El rango de edades donde se encontró mayor presencia de maltrato fue entre los 21 y 22 años. Así mismo, el tipo de maltrato con mayor frecuencia fue el psicológico, seguido por el emocional, el físico, económico y, por último, el maltrato sexual.
El ecohéroe escolar como figura arquetípica para la niñez
Authors: Bolaños Motta José Ignacio , Chávez Ospina Laura Rocío , Sánchez Rodríguez Carlos Alfonso
Published: April 2021

El presente artículo expone los alcances de un estudio que tuvo como objetivo fortalecer el sentido de la responsabilidad hacia el manejo de los residuos sólidos de los estudiantes de preescolar de la Institución Educativa Jorge Eliécer Gaitán Ayala de Villavicencio (Meta). A través de un enfoque cualitativo desarrollado a partir de dos propuestas metodológicas; a saber, la investigación creación y la investigación acción, se llevaron a cabo actividades escolares relacionadas con la creación de dos superhéroes. La categoría de ecohéroe escolar, a la cual pertenecen estos superhéroes, buscó sensibilizar a la comunidad estudiantil sobre el correcto manejo de los residuos sólidos. Como resultado, se encontró que los niños fueron influenciados por el ecohéroe y desarrollaron una toma de conciencia sobre el manejo de los residuos en la institución.
Desarrollo de experiencias emocionales en educación
Authors: Barrios-Tao Hernando
Published: April 2021

El fortalecimiento de habilidades socioemocionales es un desafío para los ámbitos laboral, político y educativo, e indica una ruta para comprender el desarrollo de las experiencias emocionales: propósito de la educación emocional. El objetivo de este artículo fue determinar, en resultados investigativos realizados por educadores, principios y acciones para la comprensión de los episodios emocionales en educación que podrían contribuir con la formación humanística. La metodología correspondió a una revisión narrativa de carácter selectivo. Los criterios de inclusión se determinaron por aspectos temporales (2000-2018), de publicación (revistas situadas en sistemas y bases internacionales: Scopus, Science Direct, Ebsco, Proquest, Dialnet), tipología (estudios teóricos, de revisión o reflexión; investigaciones cualitativas o cuantitativas; investigaciones realizadas por educadores en el aula). Los resultados trazan principios orientadores como la comprensión del acto educativo como un acto emocional, la consideración de la complejidad y la dimensión múltiple de las emociones, así como la atención a teorías de aprendizaje que contribuyan con el desarrollo emocional. Tanto los principios como las acciones halladas fundamentan las prácticas para comprender el desarrollo emocional en el ámbito educativo y podrían contribuir con la formación humana de los actores educativos.
La Ciencia Política a través de sus manuales
Authors: Barrientos del Monte Fernando
Published: April 2021

En este artículo se elabora un recorrido del desarrollo de la ciencia política en México y en América Latina desde la perspectiva interna de la historia de la ciencia. A partir de una selección de manuales de ciencia política escritos y/o traducidos al español, se analizan los temas, los paradigmas y las metodologías que han dominado la disciplina en diversos periodos, desde principios del siglo XX hasta las primeras décadas del siglo XXI. En los manuales están contenidos los alcances y objetivos de una disciplina, delimitados por la comunidad científica que la cultiva, de esta manera son un objeto esencial para comprender la sociología de la ciencia política. Se identifican cuatro tendencias teórico metodológicas en igual número de periodos: filosófico-institucionalista, legal institucionalista, sociológico funcionalista y marxista, y finalmente democrático-pluralista. Se destaca que la ciencia política surgió con una baja independencia de otras disciplinas, y en la actualidad tiene sus propios paradigmas y teorías, y ha incorporado nuevas temáticas como reflejo de los cambios histórico políticos en la región.
Guerra Fría en las aulas
Authors: Garzón Vallejo Iván , Ramírez Sarmiento Diana María
Published: April 2021

En este trabajo se buscó identificar la existencia de un canon de autores, escuelas y temáticas en la enseñanza de la teoría política contemporánea en los programas de pregrado de Ciencias Políticas vigentes en Colombia. A partir de dicho canon se formuló un diagnóstico de los enfoques o teorías predominantes en la enseñanza de la teoría política contemporánea tomando como criterio de análisis la forma como aquel resuelve cuatro tensiones epistemológicas de la subdisciplina: monismo vs. pluralismo, local vs. global, modernidad vs. posmodernidad y disciplinar vs. Interdisciplinar. La solución de estas tensiones permitió concluir que el canon se caracteriza por una perspectiva pluralista, interdisciplinar, local y moderna y evidencia un proceso de redefinición de sus fronteras problemáticas, así como un espíritu relativamente refractario al influjo de la teoría política anglosajona.
Cartografías de la ciencia política argentina
Authors: Salatino Maximiliano , Gallardo Osvaldo
Published: April 2021

El presente trabajo tuvo por objetivo realizar un mapeo del estado actual de las estructuras de producción y circulación politológica en Argentina. Este tipo de análisis se inserta dentro de una serie de estudios que han analizado las formas que ha adoptado la ciencia periférica, sus estilos de producción y circuitos de publicación. Buscamos responder una sencilla pregunta que posee respuestas complejas: ¿dónde publica la ciencia política de Argentina y qué características presentan sus investigadores/as —considerando trayectorias, estrategias y perfiles— en el CONICET? Para ello, analizamos la trayectoria de 148 investigadores/as del CONICET con el fin de comprender sus prácticas de publicación y posicionamiento en el campo científico argentino. Al mismo tiempo, examinamos el espacio de publicación de revistas de ciencia política, sus circuitos y orientaciones de circulación. Se encontró que más allá de las políticas científicas de descentralización de las actividades de ciencia y técnica, la concentración de capacidades de investigación en las zonas metropolitanas es casi absoluta. Para el caso de la ciencia política, el nodo UBA-UNSAM-UNR centraliza la mayor cantidad de investigadores/as y, por tanto, de producción politológica del país.
An interesting case of chronic myeloid leukemia (CML) with T315I mutation raising suspicion of de novo AML, a diagnostic conundrum.
Authors: Iqbal Phool , Shahzad Aamir , Shahid Zubair , Iqbal Aden , Qamar Muhammad Sohaib , Ghori Firdous , Omri Halima El , Soliman Dina
Published: April 2021

Chronic myeloid leukemia (CML) is a myeloproliferative disorder due to
translocation between chromosomes (9, 22), known as the “Philadelphia
chromosome.” In 2016, the World health organization (WHO) introduced a
new clinical entity of de novo acute myeloid leukemia (AML). Both
diseases share some commonalities, therefore, create a challenge to
diagnose.
Seed dormancy varies widely among Arabidopsis thaliana populations both between and within Fennoscandia and Italy
Authors: Zacchello Giulia , Bomers Svenja , Böhme Cecilia , Postma Froukje , Agren Jon
Published: April 2021

The timing of germination is a key life-history trait in plants, which
is strongly affected by the strength of seed dormancy. Continental-wide
variation in seed dormancy has been related to differences in climate
and the timing of conditions suitable for seedling establishment.
However, for predictions of adaptive potential and consequences of
climatic change, information is needed regarding the extent to which
seed dormancy varies within climatic regions and the factors driving
such variation We planted 17 Italian and 28 Fennoscandian populations of
Arabidopsis thaliana in the greenhouse and at two field sites in Italy
and Sweden. To identify possible drivers of among-population variation
in seed dormancy, we examined the relationship between seed dormancy and
climate at the sites where populations were originally sampled. Seed
dormancy was on average stronger in the Italian compared to the
Fennoscandian populations, but also varied widely within both regions.
Estimates of seed dormancy in the three maternal environments were
positively correlated, but seeds had on average stronger dormancy when
produced in the greenhouse than at the two field sites. Among
Fennoscandian populations, seed dormancy tended to increase with
increasing summer temperature and decreasing precipitation at the site
of origin. In the smaller sample of Italian populations, no significant
association was detected between mean seed dormancy and climate at the
site of origin. The correlation between seed dormancy and climatic
factors in Fennoscandia suggests that at least some of the
among-population variation is adaptive and that climate change will
affect selection on this trait.
Working equation of LR-TD-DFT First-order polarization propagator approximation
Authors: Pedersen Jacob , Mikkelsen Kurt
Published: April 2021

We present the derivation of a new response method termed rst order po-
larization propagator approximation. The electronic structure is given
by a density functional representation. We provide a detailed derivation
of the method along with explicit expressions for the relevant integrals
and matrix elements.
Waste generation as a side impact of COVID-19 pandemic: Communication on correct disposal of single-use face masks
Authors: Tomaszewski Débora
Published: April 2021

The rapid global spread of SARS-CoV-2 and the resulting Coronavirus
disease (COVID-19) pandemic has led to urgent efforts to contain and
mitigate transmission. The use of face masks became a primary measure to
limit the spread, which increased the production and consequent waste
generation. It is estimated that globally 129 billion single-use face
masks are discharged into the environment every month. Besides to add to
already great concerns over plastic pollution, contaminated face masks
not properly handled also poses a health risk. The health and
environmental consequences caused by the inadequate disposal of
single-use face masks are treated in this study as an eminent risk to be
properly communicated. This study framed the waste generation as a side
impact of the COVID-19 pandemic and analysed how the communication has
been made regarding the correct disposal of single-use masks, with focus
in users of public transport in Stockholm region. National and regional
authorities are recognized as the main responsibles for the
communication about correct disposal, together with manufacturers and
suppliers of single-use face masks. Disclosure and informative material
of four government authorities and instruction manuals of eight brands
of single-use face masks are analysed according to: i) presence /
absence of information (about the disposal); ii) type of communication
(visual or written); iii) message transmitted and; ix) availability in
other languages. It was found guidance about correct disposal of face
mask in two thirds of the existing communication, that is mainly written
and with few visual aids. Half of communication is made only in Swedish
and with no sufficient focus on the importance of correct disposal
neither with reference to trash bins with lid. It suggests that the
current communication about how to dispose single-use masks safely may
not be enough, which is affecting the perception of risk by the
population and worsening the health and environmental consequences
caused by the inadequate disposal.
EVIDÊNCIAS DO ISOMORFISMO NA GESTÃO DE RISCOS OPERACIONAIS EM INSTITUIÇÕES FINANCEIRAS QUE ATUAM NO BRASIL
Authors: Ferreira Marta Lourdes , Peleias Ivam Ricardo , Parisi Claudio
Published: April 2021

O trabalho analisou evidências do isomorfismo na Gestão de Riscos Operacionais em bancos atuantes no Brasil, buscando identificar pontos de convergência e porque ocorrem. A pesquisa é qualitativa e descritiva, realizada por análise de conteúdo do Relatório “Pilar 3” de oito instituições entre 2013 e 2019. Foram usadas categorizações descritivas de situações/eventos obtidos a partir do referencial teórico, classificáveis como referências de atuação. As principais categorias por mecanismo e índices de evidenciação foram: a) coercitivo: atendimento legal (100%); Plano de Continuidade de Negócios (100%); declaração de Apetite ao Risco (100%); gestão de outros riscos além dos obrigatórios (88%); modelo das 3 Linhas de Defesa (88%) e divulgação de perdas operacionais (88%). b) normativo: responsabilidades de comitês, diretores e assemelhados (100%); disseminação da cultura de risco (100%); treinamento em risco operacional (88%), e. c) mimético: uso de tecnologias na Gestão de Riscos Operacionais (100%); determinações da matriz (100%); padronização de procedimentos entre matriz e filiais (88%); e uso de indicadores (88%). Os pontos de convergência foram a busca pelo aperfeiçoamento da Gestão de Riscos Operacionais e o atendimento aos requisitos para aprovar modelos internos para cálculo de requerimentos de capital. A homogeneização da Gestão de Riscos Operacionais ocorreu em função das demandas legais e seus efeitos benéficos melhoram o ambiente. A divulgação de princípios, melhores práticas e Relatórios “Pilar 3” permite que outras organizações usem as informações como base e implantem suas próprias estruturas de Gestão de Riscos Operacionais.
IMPACTO DO NOVO RELATÓRIO DOS AUDITORES INDEPENDENTES NOS HONORÁRIOS DOS AUDITORES
Authors: Mello Lorena Costa de Oliveira , Araújo Paolo Giuseppe Lima de , De Luca Marcia Martins Mendes
Published: April 2021

A adoção do novo relatório dos auditores independentes acarretou novas exigências de divulgação, principalmente quanto aos Principais Assuntos de Auditoria, envolvendo riscos e procedimentos executados pela empresa auditada. Nesse contexto, analisa-se o impacto da adoção do novo formato nos honorários de auditorias realizadas nas empresas listadas na B3. Foram examinados dados de 346 empresas, abrangendo o biênio anterior à adoção do novo relatório (2014-2015) e o primeiro biênio de sua vigência (2016-2017). O resultado obtido por meio da análise de dados em painel sugere que a adoção do novo relatório não impactou os honorários de auditoria das empresas examinadas, rejeitando-se a hipótese norteadora da pesquisa de que essa nova modalidade poderia gerar um esforço adicional dos auditores independentes, devido às novas exigências de divulgação. Pode-se inferir que as alterações introduzidas pelo novo relatório não alteram substancialmente o escopo do trabalho dos auditores independentes, apenas aumentando os níveis de divulgação e de transparência sobre os procedimentos adotados. Constatou-se ainda que a divulgação dos Principais Assuntos de Auditoria relacionados aos riscos no nível de entidade impacta positivamente os honorários de auditoria. Ademais identificou-se que, exceto a variável comitê de auditoria, as variáveis complexidade, risco de litígio, risco inerente, tamanho da empresa, tipo de firma de auditoria, tipo de relatório de auditoria, rodízio de auditorias e setor econômico apresentaram relação estatisticamente significante com os honorários de auditoria. Além de contribuir para que os órgãos reguladores entendam os impactos de novas demandas no trabalho dos auditores independentes, os resultados facilitam a negociação entre as firmas de auditoria e seus clientes, ao fornecer elementos para o entendimento dos critérios de definição dos honorários dos auditores independentes.