bluuebunny/crossref_metadata_2025 huggingface dataset:
Office Building’s Occupancy Prediction Using Extreme Learning Machine Model with Different Optimization Algorithms
Authors: Motuzienė Violeta , Bielskus Jonas , Lapinskienė Vilūnė , Rynkun Genrika
Published: September 2021

Increasing energy efficiency requirements lead to lower energy consumption in buildings, but at the same time occupants’ influence on the energy balance of the building during the use phase becomes more crucial. The randomness of the building’s occupancy often leads to the mismatch of the predicted and measured energy demand, also called Energy Performance Gap. Therefore, prediction of occupancy is important both in the design and use phases of the building. The goal of the study is to apply Extreme Learning Machine (ELM) models with different optimisation algorithms – Genetic (GA-ELM) and Simulated Annealing (SA–ELM) for occupancy prediction in an office building based on measured CO2 concentrations. Both models show similar and high accuracy of prediction: R2 – 0.73–0.74 and RMSE – 1.8–1.9 for the whole measured period. Influence of population size, number of neurons, and number of iterations on results accuracy was also analysed and recommendations are given. It was concluded that both methods are suitable for occupancy prediction, but because of different simulation times, SA-ELM is recommended for the Building Management Systems (BMS), where higher speed is required.
The Funcitonalization of in Absentia Court as a Form of Corruption Crime’s Asset Recovery
Authors: Ariansyah Raffky , Sunarto Sunarto , Husin Sanusi , Nurahman Dwi
Published: September 2021

Examination of corruption cases in the absence of the defendant at trial still has many obstacles. The elucidation of Law Number 31 of 1999 as amended in Law Number 20 of 2001 concerning eradicating criminal acts of corruption, especially in Article 38, provides an opening for the judiciary in absentia as an orientation to save state assets. What is the importance of the judiciary in absentia as an effort to recover assets, how is the implementation of justice in absentia to recover assets? What is the basis for the judges' legal considerations on the implementation of the trial? Then this study uses a normative research method with a normative juridical approach, while this type of research is descriptive. Based on the discussion in the study that the importance of the in absentia judiciary as an effort to recover assets carried out by the defendant legally and appropriately summoned to eradicate the crime of corruption and recover state losses can still be implemented, the assets and all assets of the defendant based on the verdict are proven to be related to corruption. A criminal act of corruption can then be executed. The implementation of the judiciary in absentia is an effort to recover assets through a legal process by taking into account the defendant's rights. The judiciary without the presence of the defendant is guided by Law Number 31 of 1999 as amended in Law Number 20 of 2001 concerning the eradication of criminal acts of corruption in Article 38 paragraph (1). The basis for the Judge's legal considerations regarding the trial examination in the defendant's absence is to ensure legal certainty so that the prosecutor as the executor can save the country's assets with considerations of exceptionality, return, and rescue of state assets.
Grado de relación entre violencia familiar y conexiones interpersonales en progenitores de familia, Chachapoyas, Amazonas
Authors: Pizango Antich Jak Man
Published: September 2021

La investigación tuvo por objetivo determinar el grado de relación entre violencia familiar y conexiones interpersonales en los progenitores de familia de la Institución Educativa “Pedro Castro Alva” de Chachapoyas, 2017; la población estuvo circunscrita a 155 progenitores, cuya muestra obtenida mediante muestreo probabilístico fue de 64 progenitores de familia. El estudio de tipo descriptivo-correlacional, se aplicó una encuesta válida y confiable estadísticamente, para la variable violencia familiar α=0.97 y para conexiones interpersonales α=0.87. Los resultados obtenidos demuestran relación significativa entre violencia familiar y conexiones interpersonales (p < 0.05, X2 = 33.83, r = 0.185), es decir existe una relación positiva entre las variables de estudio; así mismo, se encontró que el 3% de los progenitores, presentó violencia psicológica grave y moderada y en el 44% se inicia relación de abuso; en el 70% de los progenitores no existe violencia física y en el 23% se inicia relación de abuso; el 3% de los progenitores presentó violencia económica grave y en el 56% se inicia relación de abuso; el 2% de los progenitores presentó violencia sexual grave, moderada y leve; y el 81.3% presentan un nivel de cautela de conexiones interpersonales, esto quiere decir, que el individuo se encuentra en un nivel bajo y que el nivel de estrés es muy alto. En conclusión, el estudio determinó que existe correlación significativa positiva pero muy baja estadísticamente entre violencia familiar y conexiones interpersonales en los progenitores de familia.
Correlación entre velocidad y comprensión lectora en alumnos de educación primaria, Kusu Chapi, región Amazonas
Authors: Chuintam Sanchez Abiezer , Farje Escobedo José Darwin
Published: September 2021

El presente trabajo tuvo como objetivo general determinar la correlación entre velocidad lectora y comprensión lectora en alumnos de quinto grado de educación primaria de la Institución Educativa 17347 de la comunidad de Kusu Chapi, distrito de Imaza, provincia de Bagua, región Amazonas, Perú. La investigación fue descriptiva, con diseño descriptivo correlacional. La muestra estuvo conformada por 20 alumnos. Los instrumentos utilizados para la medición de la velocidad lectura fueron una ficha de registro que permitió medir la cantidad de palabras leídas por minuto, a partir de una lectura; y para el nivel de comprensión lectora, una prueba de opción múltiple, conformada por diez preguntas, cinco de tipo literal y cinco de tipo inferencial. Según los resultados, el 70% de estudiantes en promedio, se ubican en el nivel bajo de comprensión lectora en los niveles literal e inferencial; además, el 85% tiene un nivel deficiente en la velocidad lectora; y finalmente, al comparar los hallazgos obtenidos entre el nivel de comprensión lectora y su relación con la velocidad lectora, se concluye que la comprensión lectora no es independiente del nivel de velocidad lectora de los alumnos del quinto grado, con el 95% de confianza; lo que significa que los estudiantes tienen una deficiente velocidad para leer y en consecuencia, no comprenden los textos que leen.
ОСНОВНІ ТЕНДЕНЦІЇ РИНКУ БАНКІВСЬКИХ ПОСЛУГ: КРЕДИТНИЙ ТА ДЕПОЗИТНИЙ АКЦЕНТ
Authors: Fedyshyn Maiia , Zhavoronok Artur , Abramova Alla
Published: September 2021

The article analyzes the current state of the banking system of Ukraine, defines the peculiarities of its functioning. It is determined that in recent years, in the conditions of structural reformation of the economy in the banking services market, there have been such tendencies as: rapid development of information, including banking, technologies that allow banks to expand the range of services and products they provide; restructuring of the financial and banking sectors, characterized by the emergence of new segments; increase of financial literacy of clients. The complex of measures aimed at maintaining the stable state of domestic financial and credit institutions, timely neutralization and preventing the development of destabiliz-ing tendencies is considered: providing assistance to enterprises in the search for opportunities to obtain loans for the for-mation and modernization of fixed assets; giving the state its financial and tax policies more liberal in relation to low-profit and loss-making enterprises; expanding the scope of credit to provide businesses with fixed and current assets; creation of an actively functioning system of state support of investment activity.
Opioid disposal rates after spine surgery
Authors: Howard Susanna Davis , Agarwal Anish , Delgado Kit , Rodriguez-Caceres Edward , Joshi Disha , Marcotte Paul , Ozturk Ali , Petrov Dmitriy , Schuster James , Welch William , Malhotra Neil , Ali Zarina
Published: September 2021

Background:

Diversion of prescription opioids pills is a significant contributor to opioid misuse and the opioid epidemic. The goal of this study was to determine the frequency and quantity of excess opioid pills among patients undergoing spine surgery. Further, we wanted to determine the frequency of appropriate opioid disposal.

Methods:

This was a prospective cohort study of patients undergoing elective spine surgery within a multi-hospital, academic, urban university health system enrolled in a text-messaging program used to track postoperative opioid disposal. Patients who self-reported discontinuation of opioid use but with leftover pills were contacted via telephone and surveyed on opioid disposal.

Results:

Of the 291 patients who enrolled in the text-messaging program, 192 (66%) patients reported discontinuing opioids within 3 months of surgery. Although 76 (40%) reported excess opioid pills after cessation of use, only 47 (62%) participated in the telephone survey regarding opioid disposal. The median number of leftover pills among these 47 patients was 5 (5, 15) and 64% had not disposed of their prescription.

Conclusion:

Among the 47 telephone survey participants, a persistent gap remained in postoperative opioid excess and improper disposal. Future efforts must focus on initiatives to improve opioid disposal rates to reduce the quantity of opioids at risk for diversion and to reduce excess prescribing.
Indonesian and Malaysian Press Policy: Pre and Post-Independence
Authors: Samsudin Dafrizal , Faridah Ibrahim
Published: September 2021

Indonesia and Malaysia are the two countries that come from a family of the Malay Archipelago. These two countries were born after a different colonial occupation namely the Netherlands and the United Kingdom. However, each country has a different press system and policy. This study aims to look at the main objectives of Indonesian and Malaysian press policy trough critical reviews of secondary data obtained from library research based on categories in two stages of newspaper development in pre and post-independence.  This study found that, in Indonesia, in the pre-independence era, the main objectives of Indonesian press policy were to control security and public order, and abuse of the press, during the Japanese occupation as Preventive censorship, and Propaganda. In the Post-Independence, the main objectives policy of the press namely as Freedom of Press, support 'political manifesto' and Implementing the "Pancasila Press System". Meanwhile, In Malaysia, in the pre-independence era, the main objective of the policy press was as controlling the press as a medium of internal racial conflict among the Chinese in Singapore and Kuala Lumpur due to differences of support for the Chinese monarchy since 1911, and propaganda machinery. In Post-Independence, the main objective of the press is to control and maintain the political stability of the country and prevent racial riots due to political and economic crisis.  This study concludes that the main objectives of the Indonesian and Malaysian Press Policy are made in accordance with the direction of the system and political policies of the ruling regime.
The role of von Willebrand factor in the development of systemic infl ammation, coagulopathy and organ dysfunctions
Authors: Лянгузов А.В. , Сергунина О.Ю. , Игнатьев С.В. , Ковтунова М.Е. , Калинина С.Л. , Семакин А.С.
Published: September 2021

Фактор фон Виллебранда (vWF) является мультимерным гликопротеином, который играет ключевую роль в осуществлении тромбоцитарного и плазменного гемостаза. В последние годы выявлено участие vWF в ангиогенезе, апоптозе нормальных и опухолевых клеток, определена его транспортная роль. Комплекс vWF и фермента ADAMTS-13, который отвечает за его расщепление, имеет существенное значение в развитии воспалительных процессов. Механизмы такого участия vWF различны и включают в себя взаимодействие с микроорганизмами, форменными элементами крови и продуктами их распада, внеклеточными ловушками нейтрофилов, системой комплемента и др. Уникальные свойства молекулы vWF при сепсисе способствуют развитию и прогрессированию коагулопатии. Системное воспаление вносит дополнительный вклад в опосредованное ADAMTS-13 локальное ингибирование расщепления vWF и усугубляет дисбаланс соотношения vWF/ADAMTS-13, тем самым способствуя развитию распространенной внутрисосудистой коагуляции. Образование ультрабольших мультимеров vWF и дефицит ADAMTS-13 выявлены при сепсисе, тяжелом течении COVID-19, черепно-мозговой и сочетанной травме, остром повреждении почек и др. В основе патогенеза возникающей при этом полиорганной недостаточности лежит развитие микроангиопатии и микрососудистых тромбозов. Возможными методами коррекции нарушений в системе vWF/ADAMTS-13 являются применение терапевтического плазмообмена, гепарина, N-ацетилцистеина, рекомбинантного ADAMTS-13, препаратов магния.

Von Willebrand factor (vWF) is a multimeric glycoprotein that plays a key role in platelet and plasma hemostasis. In recent years, the involvement of vWF in angiogenesis, apoptosis of normal and tumor cells has been revealed, and its transport role has been determined. The complex of vWF and enzyme ADAMTS-13, which is responsible for its splitting, is essential in the development of inflammatory processes. The mechanisms of vWF participation in inflammatory processes varies and include interaction with microorganisms, blood cells and their degradation products, neutrophil extracellular traps, the complement system, etc. The unique qualities of the vWF contribute to the development and progression of coagulopathy in sepsis. Systemic inflammation enhances local inhibition of vWF cleavage and exacerbates an imbalance in the vWF/ADAMTS-13 ratio, which contributes to the development of intravascular coagulation. The formation of ultralarge vWF (ULvWF) multimers and ADAMTS-13 deficiency were detected in sepsis, severe COVID-19, craniocerebral and concomitant trauma, acute kidney injury, etc. The pathogenesis of the resulting multiple organ failure due to the accumulation of ULvWF is based on the development of microangiopathy and microvascular thrombosis. Possible methods for correcting disorders in the vWF/АDAMTS-13 system are the use of therapeutic plasma exchange, heparin, N-acetylcysteine, recombinant ADAMTS-13, and magnesium preparations.
Thrombin generation assay for hemostasis assessment in trans- latitudinal Arctic voyage
Authors: Воробьева Н.А. , Воробьева А.И. , Марусий А.А.
Published: September 2021

Введение. Существуют данные об активации системы гемостаза в виде формирования гиперкоагуляции при вахтовой работе в циркумполярных территориях. Новым перспективным методом, способным оценить как гипер-, так и гипокоагуляционные состояния, является тест генерации тромбина (ТГТ). Цель исследования: анализ динамики параметров ТГТ в условиях трансширотного морского арктического рейса. Материалы и методы. Выполнено проспективное клинико-лабораторное исследование во время трансширотной экспедиции «ТрансАрктика-2019». Отбор образцов плазмы для ТГТ у 52 членов экспедиции выполнен в нулевой точке (г. Архангельск, 64°33’ с. ш., 40°32’ в. д.) до выхода судна в рейс и в самой высокой точке экспедиции (остров Хейса, архипелаг Франца–Иосифа, 80°34’ с. ш., 57°41’ в. д.) на 18–20-е сутки арктического рейса. Параметры кинетики тромбина определены на анализаторе Ceveron- alpha с TGA-модулем (Technoclone, Австрия). Результаты. В высокой точке транширотного рейса время лаг-фазы (tLag) и время достижения пика тромбина (tPeak) были значимо меньше, чем в исходной нулевой точке, что указывало на состояние гиперкоагуляции. Значения эндогенного потенциала тромбина (AUC) у членов экспедиции были существенно больше в высокой точке экспедиции. Заключение. Нахождение в высоких широтах возможно связано с формированием состояния гиперкоагуляции.

Background. Data are exist about hemostasis activation in the form of hypercoagulation during rotational work in circumpolar territories. Thrombin generation assay (TGA) is a new perspective method for assessing both hyper- and hypocoagulation. Objectives: to analyze the dynamics of TGA parameters in trans- latitudinal Arctic sea voyage. Patients/Methods. A prospective clinical and laboratory study was carried out in 52 expedition members during the trans- latitudinal expedition “TransArktika-2019”. Plasma samples for TGA were taken at the zero point (Arkhangelsk, 64°33’ N, 40°32’ E) prior to the ship’s voyage and at the highest point of the expedition (Heiss Island, Franz Josef Land, 80°34’ N, 57°41’ E) on 18–20 days of the voyage. Thrombin kinetic parameters were determined on a Ceveron-alpha analyzer with a TGA-module (Technoclone, Austria). Results. At the highest point of the trans-latitudinal voyage, the lag phase (tLag) and the time to peak thrombin (tPeak) were statistically less than at the initial zero point that pointed to hypercoagulation. The endogenous thrombin potential (AUC) values were significantly higher at the highest point. Conclusions. Location in high latitudes is possibly associated with the formation of hypercoagulation.
Mídia, celebrização e música popular: o caso de Dalva de Oliveira e Herivelto Martins
Authors: Vargas Herom , Bruck Mozahir Salomão
Published: September 2021

A partir da famosa polêmica do casal de cantores Dalva de Oliveira e Herivelto Martins, entre as décadas de 1940 e 1950, este artigo busca discutir como a busca pela fama, dentro do sistema industrial de produção e circulação da canção, e os interesses mercadológicos de gravadoras e emissoras de rádio permitiram a midiatização da vida privada e íntima desses artistas. Para a análise, usaremos estudos sobre a configuração da indústria fonográfica e do rádio no período, além de noções como glamourização e celebrização. A polêmica midiática estabelecida entre o casal será tratada a partir de 16 canções gravadas por ambos no final do casamento e após a separação e pela repercussão na imprensa. São boleros, sambas e sambas-canções, compostos entre 1947 e 1952 por Herivelto e parceiros (gravadas pelo seu Trio de Ouro), e por autores que compuseram para Dalva.
As “crianças da zika” segundo nos contaram os jornais brasileiros: uma leitura retrospectiva a partir da cobertura noticiosa
Authors: Barros Alessandra Santana Soares e
Published: September 2021

Parte-se da premissa de que a epidemia de Zika seria uma história não acabada, na medida em que suas consequências se estenderão para sempre. Estão estampadas nas sequelas sofridas pelas crianças acometidas pela síndrome congênita – deficientes múltiplos, que seguirão demandando, de suas famílias e do Estado, cuidados perenes. Desse modo, foi encaminhada uma pesquisa documental que analisou a narrativa de jornais brasileiros de grande circulação sobre a Síndrome Congênita do Zika-Vírus/Microcefalia, recortada ao longo dos dois e meio primeiros anos da cobertura noticiosa. Interessava saber como se deu o enquadramento discursivo acerca dos efeitos dos danos neurológicos e das anomalias, na infância e na vida futura dos bebês afetados. Conclui-se que essa permanência histórica da epidemia de microcefalia e, portanto, da Síndrome Congênita do Zika, não foi adequadamente antecipada pelos jornais que noticiaram o fenômeno naquela época.
Editorial
Authors: História da Mídia Associação Brasileira De Pesquisadores de
Published: September 2021

Editorial
The "Taranaki Type": C.H. Moore and the "revolutionary" fresh-air classroom design
Authors: Naus Natasha
Published: September 2021

Charles Howard Moore was the Taranaki Education Board Architect from 1920-43. During his tenure Moore developed an open-air classroom design that he called the "Taranaki type"; a design that he claimed was an improvement on the "Fendalton type" of Christchurch. The first Taranaki "fresh air classroom" was opened in New Plymouth in 1928. The "Taranaki type" embraced the principles of natural light and fresh air in an innovative and thoughtful way that took into consideration climatic conditions and the needs of the users. Moore's distinctive design dominated classroom construction throughout the Taranaki region and many of them continue to be used for educational purposes. The New Zealand Historic Places Trust has registered examples of the Taranaki fresh-air classroom and many have been identified by local councils for their architectural and technological values. However, little has been written about CH Moore - his life, training, experiences, and influences. Was he a lone practitioner of the open-air design? Was his design "revolutionary"? Were his classrooms successful? Utilising a variety of archival sources, genealogical research, and comparative analysis, this paper will reveal a more detailed picture of CH Moore and examine his contribution to the design of educational buildings in New Zealand.
Colour, Hell of a Good Thing!
Authors:   , Burke Belinda
Published: September 2021

Although the importance of colour as a fundamental element in architecture has heightened in literature recently, there is little research that explores the potential for its use in New Zealand. This design-led research explores how Mexican Architect Luis Barragan’s strategies in choreographing magical atmospheres through light and colour can influence contemporary architectural practice in New Zealand. Three predominant strategies are determined; coloured light, coloured latticework and planes of colour. Analogue design experiments engaging with the analysis of these strategies provoke further enquiries. This research investigates how the design of a residential house in South Wairarapa seeks integration with Barragan’s light/colour strategies from Mexico. This is influenced by a photographic and illustrated analysis of the site’s climatic characteristics and architectural context of the region, and is subsequently tested through the design processes and methodology of Barragan’s including written narratives, sketching and physical modelling. Finally, exterior and interior colour schemes are visualised through drawings that interrogate relationships between the proposed architecture and its surrounding environment and atmospheres desired. This research demonstrates one approach to designing with light and colour for New Zealand architecture to generate emotional, magical atmospheres. The findings of this research suggest that the element of contrast is important in generating the mysterious or unexpected, giving impact to the extraordinary quality of coloured moments. It further acknowledges that the public concern of colour is just as crucial as its private concern, and both must be considered with respect to the project’s individual context. It is hoped that this research will raise confidence in using colour in New Zealand as a powerful spatial tool and means to express individuality and identity. 
Analysis of Distance Learning for Foreign Students during Quarantine
Authors:   Poltava, Poltava State Medical University. 23, Shevchenka St., Poltava 36000, Ukraine, Yeroshenko G. A. , Klepets O. V. , Perederii N. O. , Ulanovska-Tsyba N. A. , Vatsenko A. V.
Published: September 2021

Nowadays, the attention of researchers is attracted by issues related to the study of the effectiveness of distance learning. And there is also an ongoing discussion about the disadvantages and advantages of the methods that are used in online training during quarantine. The purpose of the study was to conduct an anonymous survey of the 1st year students of the English-language form of study, in order to identify the objective attitude of students to distance learning during quarantine and to determine its advantages and disadvantages, taking into account the proposals from foreign students. Materials and methods. The study was carried out among the 1st year English-speaking students of the International Faculty about the online form of education, during quarantine, using the questionnaire "Distance learning during quarantine" developed by the psychologist T.M. Klimach. The questionnaire contained 10 questions that had one or more correct answers (at the request of the students). 50 students took part in the survey. Results and discussion. As a result of the study, it was established that the majority of students are aware of the seriousness of the epidemiological situation and the need for online learning. The most conscientious part of the respondents blamed themselves for the difficulties of distance learning, pointing out self-discipline and a serious attitude to learning as the basis for success. Among the advantages of distance learning, students noted an additional incentive and new opportunities for self-education and an increase in the time free from classes. And the disadvantages of the distance form are considered excessive workload and lack of personal contact with teachers. Among the proposals for improving the organization of distance learning, students focused on reducing the volume and complexity of tasks, increasing the teacher's explanations during classes, as well as using the algorithmization of educational material and the learning process. Conclusion. In a survey of foreign students, it was determined that the organization of distance learning at Poltava State Medical University received a positive assessment. Some students noted the support of teachers and saw new opportunities for themselves to acquire knowledge. Most respondents blamed self-discipline and a serious attitude to learning for the difficulties of distance learning
“Knowledge cleanses our mind and brings peace.”
Authors: Shankar Gurudev Sri Sri Ravi
Published: September 2021

None
Adenomatoid Odontogenic tumor in an 8 year old patient : Report of a case
Authors: M.D.S. Dr. G. Suchitra. , M.D.S Dr. Kango Prasad Gopal. , M.D.S Dr. Kaustubh.N.Tambekar.
Published: September 2021

Adenomatoid odontogenic tumor is a benign hamartomatous odontogenic neoplasm. This entity is more commonly seen in young individuals in second decade of life. It occurs commonly in the anterior maxillary region usually in association with impacted maxillary canine. Here, a case report in which the tumor occurred at an early age of 8 years (in the first decade of life) and associated with an unerupted first premolar tooth (which is an unusual situation) has been reported. Priority should be made on early diagnosis and proper treatment planning.
Applicability of smart phones in identification and transferring the static images of oral mucosal lesions by allied health workers- A feasibility study
Authors: Shareef Kotyal Dr. Mahammad , Nusrath Fareed Dr. , Shaik Rafi
Published: September 2021

Background: Recent years have witnessed an enormous increase in the use of smart phones by almost the entire population. These phones are devices which use satellite communication and computation which can be hand held and used at point of service delivery. Aim: This pilot study aims at training allied health workers in identifying and locating people with oral mucosal lesions using smart phone technology. Methodology: This pilot project was designed and conducted amongst allied health workers in Sullia Taluk of Dakshina Kannada District for identification and transferring the static images of oral mucosal lesions for further diagnosis and follow up. A total of six of the ten PHC’s in Sullia Taluk were selected using simple random sampling method. Allied health workers who met our inclusion criteria were included in this study. Results: Preliminary analysis of the images obtained through smartphones revealed benign lesions in 14 images (7 pairs) potentially- malignant lesions in 34 images (17 pairs) and malignant lesions in 14 images (7 pairs). Conclusion: Health care delivery using Smartphone technology can be used as a promising tool in monitoring, diagnosing of diseases and referral of patients.
Pharmacovigilance: An Emerging Trend in Dental Practice of India
Authors: Sachdev Rohan , Grag Kriti , Singh Garima , Mehrotra Vishal
Published: September 2021

Medicine plays potent part in our life, helps in curing various deadly disease. Safe administration of medicine is the chief goal of all people involved in curing the patient and prescribing medicines. Effective drug regulation is required to ensure the safety, efficacy and quality of drugs, as well as the accuracy and appropriateness of the drug information available to the public. Pharmcoviliglance is a important tool in health care field by helping in assessment, monitoring and discovery of newer drugs for the benefit of patients. Pharmcovigilance also plays role in checking drugs interaction among other drugs and adverse drug reaction of any drug which can cause harm to the humans. Dental field is involved in various drug uses in treatment of oral conditions. Dentists are aware of drugs side effects but they should be aware of adverse drug reactions of other drugs. Dental pharmacoviglance is a new important trend for dentist in treating patient with oral disease.
Influence of two different desensitizers on the shear bond strength of two newly introduced bonding agents following the total etch strategy: an in vitro study
Authors: Pandey Dr. Alok Pandey , Shetty Dr. Shibani , K B Dr. Jayalakshmi , PrasannalathaNadig Dr. , Sujatha I Dr. , Elizabeth Dr. Deena
Published: September 2021

Objective: Evaluate the shear bond strengths of two different dentin bonding agents following the pretreatment of dentine with two different desensitizing agents. Materials and methods: 60 premolar samples were grounded to expose the dentine. The teeth were categorized into three major groups. Each major group was subdivided into 2 subgroups of 10 samples each. Groups 1&2 involved no pretreatment with desensitizer prior to the bonding agents application. Groups 3&4 were pretreated with Gluma desensitizing agent prior to the use of All bond Universal as self-etching modality in group 3 and One Coat 7.0 in group 4. Groups 5&6 involved pretreatment with MS Coat One desensitizer and use of All bond Universal and One Coat7.0 bonding agents respectively. Shear bond testing of the samples were then evaluated by the universal testing machine. Analysis of the data was done using One-way ANOVA and pair-wise comparison was performed using Tukey’s multiple comparison test. Results: Control groups in which no pretreatment was done with any desensitizing agent had the highest bond strength when compared to the experimental groups. Among the desensitizers, significantly higher bond strength was shown by Gluma than MS Coat One. Conclusion: Gluma with One Coat 7.0 can be used to decrease the post-operative sensitivity without compromising bond strength.
Association between interleukin-6, C-Reactive protein and periodontal inflamed surface area : a cross- Sectional investigation
Authors: BDS Deepanwita , Madaiah Hemalata
Published: September 2021

Background and Objective: Periodontitis is a complex disease and is proven to be a risk factor for various systemic diseases by causing an inflammatory burden. CRP is an extremely sensitive marker for inflammation and its levels have been shown to be associated with periodontal inflammation. IL-6 has been shown to affect the production of CRP. To associate periodontal inflammation to any systemic disease it is necessary to quantify the amount of inflamed periodontal tissues. A new measure Periodontal Inflamed Surface Area (PISA) has been developed for the same. In the light of the above mentioned facts this study is designed to assess serum and GCF levels of CRP and IL-6 and correlate these with PISA in patients affected by chronic periodontitis. Materials and Methods: A total of 45 systemically healthy patients with chronic periodontitis participated in the study. Periodontal parameters, i.e BI, PI, CI, mean CAL and PISA (using spreadsheet by Huojel et al,2000) were recorded for all patients. GCF and serum samples were harvested from all subjects and samples were stored and analyzed for CRP and IL-6 using ELISA kits. Results: The PI, BI, CI and mean CAL had a positive correlation with PISA. BI and mean CAL had a significantly positive correlation with PISA (p<0.05). PISA also had a positive correlation with GCF levels of CRP (r=0.098, p=0.57), serum CRP levels (r=0.14, p=0.42), GCF IL-6 (r=0.89, p=0.61) and a significantly positive correlation was seen between PISA and serum levels of IL-6 (r=0.41, p=0.014). Also, there was a positive correlation between GCF and serum levels of CRP and IL-6. The serum levels of CRP and IL-6 had a significantly positive correlation (r=0.39, p=0.02). Conclusion: Higher PISA values were associated with higher serum levels of the inflammatory markers., thus proving that PISA could probably be used to correlate the local inflammatory burden with the systemic inflammatory burden.
Comparative evaluation ofantimicrobial activity of herbal oils and their ability in disinfection of gutta percha cones - Aninvitro study
Authors: Rastogi Dr.Mansi , Nadig Dr. Prasannalatha , K B Dr.Jayalakshmi , Selvan K Dr. Arul , I Dr. Sujatha , P.G. Dr. Manjegowda
Published: September 2021

Aim: The purpose of this study is to evaluate antimicrobial activity of different herbal oils and their ability in disinfection of gutta percha cones. Material and methods: Antimicrobial activity of Lemon grass oil, Cinnamonoil, Peppermintoil and sodium hypochlorite (positive control) was evaluated using Agar diffusion method against Staphylococcus aureus and E. Faecalis. Sixty gutta percha cones were glove handled during ongoing routine endodontic procedures and then cut into two equal halves. First half of contaminated gutta percha cones were placed in brothand incubated and the other halves were treated with herbal oils and sodium hypochlorite for one minute and then incubated for 24hours to check for turbidity. Results: 1)For both tested micro-organisms, Cinnamon oil showed largest zones of inhibition (mean ± SD), 28.6 ± 1.18 mm, 30.8 ± 1.4 mm against E. faecalis, S. aureus. 2)Cinnamon oil is most effective in decontamination of GP cones in 1 minute, followed by NaOCl, Lemon grass oil and Peppermint oil. Conclusion: Cinnamon oil is a potent antimicrobial agent for rapid disinfection of GP cones in one minute and can be an alternative to sodium hypochlorite.
Evaluation of efficacy of clorni* gel as an adjunct to phase 1 Therapy, in the treatment of gingivitis - A randomisedControlled clinical study.
Authors: S Dr. Sangeetha
Published: September 2021

Aim: To evaluate the efficacy of Clorni* gel as an adjunct to phase 1 therapy, in the treatment of gingivitis. Methodology: The study was carried out on 30 patients. Group 1(control group): scaling and root planing, oral hygiene instruction and Hexi* gel application. Group 2(test group): scaling and root planing, oral hygiene instruction and Clorni* gel application. Clinical parameters like Gingival Index, Plaque Index and Papillary Bleeding Index were recorded at baseline, one week and after one month for each patient. Results: There were reduction in the PI, GI and Papillary bleeding index scores in both the groups. Within the groups (group1 and group 2) clinical parameters showed overall reduction from baseline to 1 month and on multiple analysis the results were statistically significant from baseline to one month, but no statistical significance was seen from one week to one month. On comparison between the groups there was no statistical significance in the clinical parameters. Conclusion: Clorni gel can be used as an adjunct to SRP in the treatment of gingivitis.
In-vitro evaluation of intermediate irrigants for removal of para-chloroaniline from the tooth during root canal treatment
Authors: Koshy Varughese Dr Blesy , K Dr Annapoorna , I B Dr Geeta , Ganessin Aravind
Published: September 2021

Introduction: The need for root canal treatment is to eliminate bacteria from the infected canal system and to prevent recontamination. In this case, most common irrigant used in root canal treatment are sodium hypochlorite (NaOCl) and 2% chlorhexidinegluconate (CHX) have been recommended as a less toxic alternative. This treatment of using chemical irrigants for eliminating bacteria leads to a colour formation in the tooth by formation of parachloroaniline (PCA). Our study focuses on the spectrophotometric analysis of PCA formation during the NaOCl and CHX are mixed and thereby using intermediate irrigant solutions to prevention of orange brown precipitate. Spectrophotometer works on the principle of Beer Lambert’s Law in which - max determination of PCA was done using a wavelength scan between 350nm to 550nm. Furthermore, three different intermediate irrigant solutions were tested to analyse the efficient solution system for prevention of the orange brown precipitate. Group A fresh lime juice extract, group B 14.25% EDTA and group C 70% ethanol was used.Group A (lime group) exhibited the least OD value among all the experimental groups followed by group B (14.25% EDTA) and group C(70% Ethanol) and also statistically proved. Spectrophotometric analysis showed freshly prepared lime juice extract was found to be very effective in prevention of PCA precipitate followed by 14.25% EDTA and 70% ethanol. Thus, this study gives and insight about the analysis and novel ways of prevention of PCA during root canal treatment
Cherubism in a 12-year old Child; A Rare Case Report
Authors: Hiremath Dr. Mallayya C. , Srinath Dr. SK. , Balan Dr. Bineesh , H S Dr. Sushma
Published: September 2021

Cherubism is a non-neoplastic, fibro-osseous, self-limiting, autosomal dominant disorder of the jaws. It is also called as familial fibrous dysplasia and familial multi-locular cystic lesion of the jaws. Its typical dento-facial deformities are caused by mutations in the SH3BP2 gene. The lesion regresses during puberty and the disease stabilizes after the growth period. But it leaves some facial deformity along with disturbances in occlusion. Cherubism may occur as an individual case or in multiple members of the same family, oftenly in multiple generations. Radiographic examination of the lesion shows bilateral multi-locular radiolucent areas.The aim of this case report is to present a case of 12-years old cherubic child, with its clinical and radiological features and discussion about the clinical outcome.This patient was diagnosed with Cherubism and being followed up periodically.
“Knowledge is the new rich, arm yourselves with it” - Toni Payne
Authors: A Dr. Suchetha
Published: September 2021

None
Effects of Enlarged Adenoids on Craniofacial Growth in Bangalore Population – A Cross-Sectional Cephalometric Study
Authors: Arya Siddarth , HC Shashikumar , GS Shwetha , Mallikarjuna Spoorthy , T Suma
Published: September 2021

Background and Objectives: The purpose of the present cross-sectional study was to determine the effects of enlarged adenoids on the growth pattern of maxilla and mandible and to evaluate the relationship between airway size and lip strain. Methods: Pre-treatment lateral cephalograms of twenty-five children (10 boys, 15 girls) were taken. The children selected for the study were in the age group of 5 – 13 years (mean age of 10 years) during the year 2008- 11. All the tracings were made on 75µm lacquered polyester acetate tracing papers using a 0.05” lead pencil. This study assessed the associations of upper lip strain and upper pharynx size with selected cephalometric measures. The data was analyzed using SPSS (Statistical Package for Social Science, Ver.10.0.5) package. Results: The increased upper lip strain was associated with a forwardly placed maxilla, increased mandibular plane angle and upper pharynx size was associated with decrease in mandibular size (mandibular corpus size), increase in gonial angle (Ar-Go-Gn), decrease in middle third of face (N- ANS) and increase in lower jaw anterior face height (ANS- Me). Also, the dental effect of increase in the degree of mandibular incisor proclination relative to mandibular plane was observed. Conclusion: With an increase in upper-lip strain and decreased upper pharynx size, forward maxillary placement, retrognathic mandible, downward and backward rotation of the mandible, decreased middle third of face, increase in lower anterior face height and increase in degree of mandibular incisor proclination relative to mandibular plane were observed. It was inferred from the present study that a decreased upper airway affects the craniofacial skeletal growth pattern in children.
Tissue Engineering in the Craniomandibular Region: Where Do We Stand?
Authors: Shrinivasa Kamath Apoorva
Published: September 2021

The science of tissue engineering is a promising one to a craniofacial biologist with a plethora of research studies being conducted over the years. Stem cells (SCs) along with scaffolds and biological stimulants have been at the epicenter of such studies. The field has also gained importance due to prevalent drawbacks with organ transplantation, such as shortage in the number of donors coupled with other complications associated with the procedure. Moreover, it finds its applications in congenital defects as well. Several electronic databases were thoroughly researched including the Directory of Open Access Journals (DOAJ), Google scholar, Digital Dissertations and meta Register of Controlled Trials for relevant data. References and citations of articles and existing reviews were also researched. The search was confined to articles in English, published till March 2021. Casecontrol, cross-sectional, retrospective and prospective studies, systematic reviews and meta-analysis were included in this article. A hand search of the reference lists of the included articles was also carried out to include missed out articles. Here, the aim was to provide a comprehensive review of tissue engineering in general and its application in the craniomandibular region in particular to some of the potential futuristic novel methods which are being developed.
Perio Millennium The journey of periodontology from then to now
Authors: R Patnaik , A Nayak
Published: September 2021

Since the beginning of the civilisation, humans have been in a constant process of development. Along with lifestyle, healthcare developments have also been embraced in a remarkable journey through ages. With evolving lifestyle, the survival of disease-causing pathogens has also parallelly developed by sudden mutations and gradual evolution of species for their survival, demanding an improvement in healthcare facilities which include physical, mental and social well-being. The physical health care has seen an interesting journey in terms of both systemic and oral health. While we speak of health, the contribution of periodontal health is an appreciable factor determining the health of the oral cavity. Periodontal healthcare has existed, evolved and advanced with every passing day. This manuscript aimed at reviewing the history of periodontology from its earliest evidence up to the impending future of periodontology, exploring its existence from an era of prehistoric civilisation to an era which is yet to present itself.
Can Condylar Fracture Still Be Treated with Conservative Approach?? – A Retrospective Study
Authors: Awasthy Arunima , Krishna B Pramod , Singh Rajdeep , Mazhar Heena , Kumbhare Durgesh , Agrawal Palak
Published: September 2021

Background: Ideal management of mandibular condylar fractures remains controversial in maxillofacial trauma. Traditionally, conservative approach was implemented but recently ORIF (Open Reduction with Internal Fixation) has become prevalent. A difference of opinion has been acknowledged in the review of literature concerning the results achieved by open/closed reduction of fractures of the condyle in mandible. Research Objectives: To assess the preference of treatment for fractures of condyle and their indications, advantages, disadvantages and complications for open/closed reduction of fractures of condyle. Methodology: A 13-year retrospective study involving 56 patients who reported with fractures of condylar region were selected from 264 patients who experienced maxillofacial fractures. Out of them, seven were treated with ORIF, while 49 underwent closed reduction. Every patient was critically evaluated for identifying their indications, advantages, disadvantages, their effectiveness and complications of chosen interventions used in the management of condylar fractures. Findings: A male predominance was observed. Closed reduction with concomitant active physical therapy after inter-maxillary fixation gave similar results to that of open method. Conclusion: This study manifested that an appropriately followed conservative treatment provided similar clinical results when compared to ORIF for the management of condylar fractures. In cases with severe loss of height of mandible, surgical intervention is to be preferred to restore it. Further prospective randomized controlled trials with larger sample size are required to come to a decisive conclusion.
Significance of Recording Dental Morphological Features: An Aid in Personal Identification
Authors: S. Kamat Mamata , V. Datar Uma , Vadaliyac Margi , P. Wadgave Umesh , VK Varsha
Published: September 2021

Aims: To record selected dental morphological features among students of our medical campus, to correlate type of dental features in males and females and to maintain records of these dental features among the study population as database for personal identification. Methodology: The present cross-sectional survey was carried out among students of Bharati Vidyapeeth Medical Campus, Sangli aged between 18-25 years. The detailed clinical examination was done to record various dental morphological features. Descriptive statistics were employed. Results: Overall, 720 students from the medical, dental and nursing colleges of our medical campus took part in the survey, consisting of 309 (42.91%) males and 411 (57.08%) females. The selected dental features were observed in 13.7% (n=97) of subjects. The most frequent features detected were talon’s cusp & cusp of Carabelli and the least being parastyle, protostylid and fusion. Cusp of Carabelli showed frequent bilateral presence than unilateral. Conclusion: The study findings stipulate an evolutionary reduction in the size of human dentition. The study highlighted the necessity for understanding the forensic value of these dental morphological features and maintenance of dental records as an adjuvant in person identification.