bluuebunny/crossref_metadata_2025 huggingface dataset:
Optimalisasi Fungsi Penegakan Hukum Dalam Menjamin Pemerataan Layanan Kepolisian
Authors: Saputra Azis , Saputra Rizki
Published: July 2023

Pelayanan tugas kepolisian di bidang penegakan hukum khususnya di tingkat Polsek pada dasarnya sudah dilaksanakan dengan baik. Namun pelayanan terhadap masyarakat yang tinggal di pedalaman, perbukitan, pegunungan, kepulauan, atau lokasi yang sulit terjangkau masih perlu ditingkatkan agar pemerataan pelayanan kepolisian di masyarakat dapat terjamin. Pentingnya dilakukannya penelitian tersebut  dikarenakan kondisi geografis di wilayah hukum Polsek memiliki karakteristik, tingkat kerawanan yang berbeda–beda, dan tingkat keterjangkauan yang beragam.  Ada yang bisa ditempuh dalam waktu puluhan menit dan ada juga yang membutuhkan waktu tempuh puluhan jam karena kondisi wilayah yang sulit dijangkau, kondisi wilayah yang dipisahkan oleh lautan, kondisi wilayah yang diliputi pegunungan, daerah perbatasan ataupun daerah yang merupakan pulau kecil terluar berpenghuni dan lain sebagainya. Kondisi ini tentu sangat berpengaruh terhadap kecepatan quick respon pelayanan kepolisian kepada masyarakat khususnya di bidang penegakkan hukum. Penelitian ini dilakukan di 8 (Delapan) Polda pada Bulan November 2020. Penelitian ini menggunakan pendekatan kualitatif dengan memakai panduan wawancara serta pengumpulan data sekunder. Responden dan informan adalah para Kapolsek, Kasat Reskrim, Kasat Lantas, Kanit Reskrim, Penyidik Pembantu dan masyarakat. Hasil penelitian menyebutkan bahwa: 1) wacana penghapusan kewenangan penyidikan di tingkat polsek tidak diinginkan baik dari kalangan masyarakat maupun internal anggota polri; 2) Masyarakat lebih suka berurusan dengan polisi Polsek karena jarak dan waktu tempuh dekat dengan tempat tinggal serta merasa lebih mengenal polisi di Polsek; 3) Sebagian besar polsek (63% dari 347 polsek sampel penelitian) belum menerapkan Penyelesaian Perkara melalui  Keadilan Restoratif; 4) Keterbatasan kualitas penyidik/penyidik pembantu sangat berpengaruh pada kinerja penyidikan perkara pidana; 5) Kecenderungan penerimaan laporan atau pengaduan masyarakat yang tidak/belum bisa dibuat dalam bentuk Laporan Polisi di SPK Polsek dituangkan dalam bentuk Pengaduan Masyarakat (Dumas); 6) Pola penugasan rangkap pada Polsek yaitu Bhabinkamtibmas merangkap sebagai penyidik pembantu; 7) Keberadaan polsek yang memiliki wilayah perairan belum terdukung  dengan sarana transportasi air sesuai kondisi perairan wilayahnya.  Penguatan penegakan hukum di tingkat Polsek dalam memberikan pelayan prima meliputi: 1) Penegakan hukum di polsek mestinya  lebih mengedapkan   keadilan restoratif dari pada penghapusan kewenangan penyidikan; 2) Perlu dipikirkan tentang keberjalanan proses penanganan perkara; 3) Perlunya strategi penguatan Polsek yang dapat dilakukan guna optimalisasi fungsi penegakan hukum; 4) Perlunya strategi penguatan Polsek melalui redesain pola integrasi penanganan perkara antar unit kepolisian; 5) Perluya penerapan manajemen pengetahuan diterapkan sebagai salah satu penguatan Polsek guna membangun capacity building
Pengaruh Religiusitas dan Job Satisfaction terhadap Organizational Citizenship Behavior pada Anggota Brigadir di Polres Pamekasan
Authors: Susanto Hairil
Published: July 2023

Penelitian ini bertujuan untuk mengetahui adakah pengaruh religiusitas dan job satisfaction terhadap organizational citizenship behavior. Sampel penelitian ini berjumlah 122 orang anggota brigadir Polres Pamekasan. Pengambilan sampel dalam penelitian ini menggunakan teknik random sampling. Penelitian ini menggunakan metode kuantitatif. Data penelitian dianalisis dengan menggunakan teknik anakova. Hasil penelitian menunjukan adanya pengaruh religiusitas terhadap organizational citizenship behavior sebesar 6,7 %, selain itu job satisfaction juga memiliki pengaruh terhadap organizational citizenship behavior sebesar 7,1 %. Penelitian ini menunjukan bahwa anggota brigadir yang sudah menikah memiliki organizational citizenship behavior yang lebih tinggi dibandingkan anggota yang belum menikah, dan anggota brigadir yang memiliki pendapatan lebih tinggi memiliki organizational citizenship behavior yang lebih tinggi dibandingkan anggota brigadir dengan pendapatan yang lebih rendah. Penelitian selanjutnya diharapkan dapat memuat perbandingan demografis lebih banyak lagi dan melakukan penelitian pada variabel lain yang dapat meningkatkan organizational citizenship behavior.
PEMERIKSAAN KADAR GLUKOSA DARAH SEWAKTU PADA MASYARAKAT DI WILAYAH PUSKESMAS KALIBARU KOTA BEKASI
Authors: Siti Nurfajriah  , Maulin Inggriani  , Ria Amelia  , Elfira Maya Sari
Published: July 2023

Pendahuluan: Glukosa darah adalah gula yang berada dalam darah yang terbentuk dari hasil akhirkatabolisme karbohidrat. Kadar glukosa darah erat kaitannya dengan penyakit diabetes mellitus (DM).Pemeriksaan penyaring dapat dilakukan melalui pemeriksaan glukosa darah sewaktu (GDS) yang dapatdigunakan sebagai deteksi dini penyakit DM. Tujuan kegiatan pengabdian kepada masyarakat ini adalahmelihat gambaran kadar GDS di 4 posbindu (teratai 1, anggrek 1, dahlia, dan mawar) wilayah kerjaPuskesmas Kalibaru Kecamatan Medan Satria Kota bekasi. Metode: Jenis penelitian cross sectionaldengan metode pengambilan sampel secara acak. Kegiatan dilakukan pada tanggal 12 – 19 Agustus 2019.Pelaksanaan kegiatan PKM bekerjasama dengan Puskesmas Kalibaru yang melibatkan dosen, mahasiswa,kader posbindu, dan tenaga kesehatan dari Puskemas Kalibaru. Sasaran kegiatan adalah warga yangtinggal di 4 wilayah posbindu. Pemeriksaan glukosa darah sewaktu menggunakan metode point of caretesting (POCT). Hasil: Hasil pemeriksaan menunjukkan responden yang memiliki kadar GDS < 70mg/dL sebanyak 1 orang (1%) dan GDS > 200 mg/dl sebanyak 21 orang (11%). Kadar GDS > 200mg/dL lebih didominasi pada responden perempuan sebanyak 81% dan laki-laki 19%. Responden denganrentang usia 55 – 64 tahun memiliki kadar GDS > 200 mg/dL sebanyak 43%. Kesimpulan: 52% wargayang ditinggal di 4 wilayah posbindu memiliki kadar GDS normal.
STUDI TINGKAT PENGETAHUAN AKSEPTOR TENTANG EFEK SAMPING PIL KB KOMBINASI
Authors: Primihastuti Dianita , Rhomadona Shinta Wurdiana , Intiyaswati Intiyaswati
Published: July 2023

Keluarga berencana adalah suatu program pemerintah untuk menjarangkan/ merencanakan jumlah dan jarak kehamilan dengan menggunakan alat kontrasepsi. pil KB, yaitu kontrasepsi yang digunakan untuk mencegah terjadinya kehamilan, mengandung hormon estrogen dan progesteron dengan cara minum pil setiap hari secara teratur. Selama ini masalah yang dihadapi para pengguna pil KB adalah efek samping pada masa adaptasi. Efek samping tersebut meliputi mual, perdarahan bercak, pusing, nyeri payudara, berat badan naik, amenorea, dan penurunan gairah seks. Tujuan dari penelitian ini adalah untuk mengetahui tingkat pengetahuan akseptor tentang efek samping pil KB Kombinasi. Berdasarkan tujuan penulis, desain penelitian yang digunakan adalah desain deskriptif. Populasi penelitiannya adalah akseptor pil KB Kombinasi di PMB Any Iswahyuni, Amd. Keb Demak Surabaya pada tanggal 1-14 April 2023 sebanyak 32 akseptor. Sampel yang diambil dengan cara purposive sampling sebanyak 30 akseptor. Dari hasil penelitian ini didapatkan tingkat pengetahuan akseptor tentang efek samping pil KB Kombinasi di PMB Any Iswahyuni, Amd. Keb yaitu 3 akseptor (10%) berpengetahuan baik, 7 akseptor (23%) berpengetahuan cukup dan 20 akseptor (67%) berpengetahuan kurang, sehingga dapat disimpulkan bahwa tingkat pengetahuan akseptor tentang efek samping pil KB Kombinasi di PMB Any Iswahyuni, Amd. Keb yang terbanyak adalah kurang. Dengan demikian diharapkan tenaga Kesehatan meningkatkan upaya-upaya untuk menambah pengetahuan akseptor pil KB Kombinasi di PMB Any Iswahyuni, Amd. Keb.
The Smart Home and Telemedicine for Senior Citizens
Authors: Абдулкина Н. Г. , Замятин Н. В. , Смирнов Г. В.
Published: July 2023

концепция умной среды обитания для здоровья пожилых людей должна обеспечить достойную жизнь в своих домах пожилым людям. В статье показан интеллектуальный подход, представляющий объединение умного дома и телемедицины на основе применения таких технологических областей, как информационные системы, техническое обеспечение умного дома, повсеместные датчики, роботизированная поддержка. Рассмотрена необходимость стандартизации и некоторые этические представления.

the concept of Smart Habitat for the Health of the Seniors shall provide a decent living for the elderly in their homes. The paper presents an intelligent approach combining the smart home and telemedicine through information systems, smart home hardware, ubiquitous sensors, and robotics. Standardization and some ethical issues are also considered.
MAESSTRO: Masked Autoencoders for Sea Surface Temperature Reconstruction under Occlusion
Authors: Goh Edwin , Yepremyan Alice R. , Wang Jinbo , Wilson Brian
Published: July 2023

Abstract. This study investigates the use of masked autoencoders (MAE) to address the challenge of filling gaps in high-resolution (1 km) sea surface temperature (SST) fields caused by cloud cover, which often results in gaps in the SST data and/or blurry imagery in blended SST products. Our study demonstrates that MAE, a deep learning model, can efficiently learn the anisotropic nature of small-scale ocean fronts from numerical simulations and reconstruct the artificially masked SST images. The MAE model is trained and evaluated on synthetic SST fields and tested on real satellite SST data from VIIRS sensor on Suomi-NPP satellite. It is demonstrated that the MAE model trained on numerical simulations can provide a computationally-efficient alternative for filling gaps in satellite SST. MAE can reconstruct randomly occluded images with a root mean squared error (RMSE) of under 0.2 °C for masking ratios of up to 80 %. It has exceptional efficiency, requiring three orders of magnitude (a factor of 5000) less time. The ability to reconstruct high-resolution SST fields under cloud cover has important implications for understanding and predicting global and regional climates, and detecting small-scale SST fronts that play a crucial role in the exchange of heat, carbon, and nutrients between the ocean surface and deeper layers. Our findings highlight the potential of deep learning models such as MAE to improve the accuracy and resolution of SST data at kilometer scales. It presents a promising avenue for future research in the field of small-scale ocean remote sensing analyses.
Extending the utility of space-borne snow water equivalent observations over vegetated areas with data assimilation
Authors: Pflug Justin M. , Wrzesien Melissa L. , Kumar Sujay V. , Cho Eunsang , Arsenault Kristi R. , Houser Paul R. , Vuyovich Carrie M.
Published: July 2023

Abstract. Snow is a vital component of the Earth system. Yet, no snow-focused satellite remote sensing platform currently exists. In this study, we investigate how synthetic observations of snow water equivalent (SWE) representative of a synthetic aperture radar remote sensing platform could improve spatiotemporal estimates of snowpack. We use an Observation System Simulation Experiment, specifically investigating how much snow simulated using popular models and forcing data could be improved by assimilating synthetic observations of SWE. We focus this study across a 24°-by-37° domain in the Western United States and Canada, simulating snow at 250 m resolution and hourly timesteps in water-year 2019. We perform two data assimilation experiments, including: 1) a simulation excluding synthetic observations in forests where canopies obstruct remote sensing retrievals, and 2) a simulation inferring snow distribution in forested grid cells using synthetic observations from nearby canopy-free grid cells. Results found that assimilating synthetic SWE observations improved average SWE biases at peak snowpack timing in shrub, grass, crop, bare-ground, and wetland land cover types from 14 %, to within 1 %. However, forested grid cells contained a disproportionate amount of SWE volume. In forests, SWE mean absolute errors at peak snowpack were 111 mm, and average SWE biases were on the order of 150 %. Here, the data assimilation approach that estimated forest SWE using observations from the nearest canopy-free grid cells substantially improved these SWE biases (18 %) and the SWE mean absolute error (27 mm). Simulations employing data assimilation also improved estimates of the temporal evolution of both SWE and runoff, even in spring snowmelt periods when melting snow and high snow liquid water content prevented synthetic SWE retrievals. In fact, in the Upper Colorado River basin, melt-season SWE biases were improved from 63 % to within 1 %, and the Nash Sutcliffe Efficiency of runoff improved from –2.59 to 0.22. These results demonstrate the value of data assimilation and a snow-focused globally relevant remote sensing platform for improving the characterization of SWE and associated water availability.
CSDMS Data Components: data-model integration tools for Earth surface processes modeling
Authors: Gan Tian , Tucker Gregory E. , Hutton Eric W. H. , Piper Mark D. , Overeem Irina , Kettner Albert J. , Campforts Benjamin , Moriarty Julia M. , Undzis Brianna , Pierce Ethan , McCready Lynn
Published: July 2023

Abstract. Progress in better understanding and modeling Earth surface systems requires an ongoing integration of data and numerical models. Advances are currently hampered by technical barriers that inhibit finding, accessing, and executing modeling software with related datasets. We propose a design framework for ‘Data Components’: software packages that provide access to particular research datasets or types of data. Because they use a standard interface based on the Basic Model Interface (BMI), Data Components can function as plug-and-play components within modeling frameworks to facilitate seamless data-model integration. To illustrate the design and potential applications of Data Components and their advantages, we present several case studies in Earth surface processes analysis and modeling. The results demonstrate that the Data Component design provides a consistent and efficient way to access heterogeneous datasets from multiple sources, and to seamlessly integrate them with various models. This design supports the creation of open data-model integration workflows that can be discovered, accessed, and reproduced through online data sharing platforms, which promotes data reuse and improves research transparency and reproducibility.
PENGARUH PEMBERIAN KALIUM TERHADAP FISIOLOGIS DAN MORFOLOGIS KEDELAI PADA CEKAMAN KEKERINGAN
Authors: Fahri Romi , Khairani Siti
Published: July 2023

Domestic soybean production is weakened by the problem of drought stress that affects all aspects of plant growth and metabolism, while an alternative that can be used is the use of potassium. Potassium is believed to have an important role in increasing plant tolerance to drought. This study aims to examine the effect of potassium application on the physiological and morphological of drought-stressed soybean. The research was conducted in a plastic house in Aras Kabu Village, Beringin Subdistrict, Deli Serdang Regency, North Sumatra using a group randomized design with two factors and three replications. The first factor was soil moisture condition consisting of 80% KL (field capacity) and 40% KL. The second factor was potassium fertilizer application of 100 kg/ha, 200 kg/ha, 300 kg/ha, and no potassium fertilizer. The observed variables were total sugar and leaf area. The results showed that the use of potassium can increase the value of total sugar and leaf area of drought-stressed soybean. Application of K dose of 100 kg/ha (0.5 g/polybag) is the most appropriate to encourage physiological and morphological drought stressed soybean plants.
Heavy Metal Concentrations in Mollusks and Crustaceans Harvested from Eastern Samar’s Taft River in the Philippine and the Health Risks Posed to Consumers
Authors: Cabahug Madel Reina , Ultra Venecio , Morallos Shian , Lanuza Nancy , Espejon Eduardo , Tan Zaldee Nino , Bejar Feleciano
Published: July 2023

Heavy metal (HM) contamination from mining activities poses a health risk to humans who consume mollusks and crustaceans from mine-affected environments. One such example is the Taft River, which receives drainage water and sediments from the Bagacay mines in Samar, Philippines. To assess the accumulation of HM in mollusks and crustaceans and the associated risks to the humans, a comprehensive analysis was conducted on representative specimens, which were gathered from different sections of the river. The concentrations of Cu (97.67 mg kg–1), Ni (29.30 mg kg–1), Pb (0.59 mg kg–1), and Sr (14.67 mg kg–1) in the flesh of “bebe” (Batissa violacea Lamarck) were significantly higher than those in “tangili” (Telescopium telescopium Linn.), “tuway” (Mercenaria mercenaria Linn.), and “sihi” (Nerita albicilla Linn.); whereas for crustaceans, the flesh of mud crabs (Scylla serrata) contained higher concentrations of As (17.67 mg kg–1), Cu (118.67 mg kg–1), Ni (25.79 mg kg–1), Rb (31.33 mg kg–1), Sr (60.67 mg kg–1), and Zn (331.00 mg kg–1) compared with giant freshwater prawns (Macrobrachium rosenbergii). The consumption of T. telescompium, N. albicilla, and B. violacea may result in an estimated daily intake (EDI) that is greater than the provisional tolerable daily intake (PTDI) for As [2.03–4.48 μg kg–1 body weight (BW) d–1], while all mollusks may have an EDI for Cr of between 124.59–136.23 48 μg kg–1 BW d–1. This may subsequently lead to a high target hazard quotient (THQ), high hazard index (HI), and high target cancer risk (TCR) for adults. With respect to crustaceans, the consumption of S. serrata exceeds the PTDI index for As. Both S. serrata and M. rosenbergii exceed the PTDI for Cr by 20–21 times, as well as the elevated health risk values of 22.36 and 28.57 48 μg kg–1 d–1 for M. rosenbergii and S. serrata, respectively. Overall, current results indicate that human consumption of the Taft River mollusks and crustaceans may inadvertently lead to an increased intake of As and Cr that could negatively impact human health.
Metaverse dalam Pembuatan dan Penggunaannya: Kegiatan Metaverse di Bidang Bisnis Online dan Pengaturannya di Indonesia
Authors: Abbydzar Nur Fauzan Muhammad , Soerjati Priowirjanto Enni
Published: July 2023

Metaverse is a platform in a three-dimensional virtual world, where users can explore the 3-dimensional world with other Internet users using avatars by interacting like in the real world. Users can also have the same opportunity to change their economic situation in the virtual world. The metaverse becomes a means to do many things, such as social activities by creating communities in the metaverse, meetings, teaching and learning activities, and economic activities. The researcher will discuss about analyzing the impact of the metaverse on the development of the digital economy in Indonesia and what regulations are appropriate for the activities in the metaverse world. The research method used in this research is the Normative Juridical Method and Qualitative Method in which researchers will quote secondary data such as laws and regulations, scientific journals, and law books.
Individualized consideration and the growth of intra-regional trade in the East African community
Authors: Oketch Timothy C , Aden Abdikadir O
Published: July 2023

The study sought to investigate the influence of individualized consideration of the Council of Ministerson the perceived growth of Intra-Regional Trade in the EAC. The research question for the study: Howdoes individualized consideration of the Council of Ministers influence the growth of Intra-RegionalTrade in the EAC? The study adopted positivism research philosophy and explanatory sequential mixed design and was anchored on the transformational leadership theory. Population for the study was 205Senior Trade Officers and Senior technical officers at the EAC headquarters. A sample size of 152 wasdrawn using random sampling technique. Data was collected using a structured questionnairecontaining open and closed ended questions, while interview guide was used for the technical officers.Data collected was coded, cleaned and analyzed using SPSS version 24 to obtain descriptive andinferential statistics. Results showed that the individualized consideration significantly influenced thegrowth of intra-regional trade in the EAC, R2=.366, F(1,121) = 69.786, p<.05; β =.561,t(7.868)=8.354, p<.05 leading to the rejection of the null hypothesis. Based on the findings, it wasconcluded that to enhance the growth of intra-regional trade, the council should be aware that theirindividualized consideration behavior enhances the growth of intra-regional trade. The studyrecommends for further research to understand the influence of the individualized consideration of theSummit members of the EAC on the growth of intra-regional trade.
Optimasi Formula Tablet Black Garlic Menggunakan Kombinasi Laktosa dan Avicel Ph 102 dengan Metode Simplex Lattice Design
Authors: Zahroh Siti Lailatu , Nurmay Stiani Sofi , Kholifah Eva
Published: July 2023

The study aims to find out whether the combination of lactose and avicel pH 102 can be formulated into black garlic extract tablet in accordance with the Indonesian Pharmacopoeia, the influence of combination, and determine the optimum formulation of the two ingredients using the SLD method. Methods used in this research Black Garlic extract is made by maceration method with 96% ethanol solvent with an extract weight of each tablet of 400 mg. Black garlic extract tablets are made in three formulations with a ratio of lactose-avicel PH-102, namely FI (100%:0%), FII (50%:50%), and FIII (0%:100%). Result shows that the optimum formula obtained was 80% lactose and 20% avicel PH 102 with a total predicted value of 0.645. The greater the concentration of avicel PH 102 as a crushing material, the faster the time rate of destruction, the hardness decreases, and the fragility value rises. The higher the concentration of the filler, the longer the crushing time it will take. The results of the statistical analysis of the three formulas tested showed the absence of significant differences between flow time, hardness, and brittleness, while crushed time tests showed the presence of significant differences (p?0.05).

 

Tujuan penelitian ini adalah kombinasi antara laktosa dan avicel pH 102 dapat diformulasikan menjadi sediaan tablet sesuai dengan Farmakope Indonesia, pengaruh tehadap kombinasi dan penentuan formulasi yang optimum dari kedua bahan tersebut dapat dilakukan dengan metode SLD. Metode dalam penelitian ini adalah Ekstrak Black Garlic dibuat dengan metode maserasi dengan pelarut etanol 96% dengan bobot ekstrak setiap tablet 400 mg. Tablet ekstrak black garlic dibuat tiga formulasi dengan perbandingan laktosa-avicel PH-102 yaitu FI (100%:0%), FII (50%:50%) dan FIII (0%:100%). Hasil penelitian menunjukkan bahwa formula optimum yang diperoleh adalah 80% laktosa dan 20% avicel PH 102 dengan total nilai prediksi 0.645. Semakin besar konsentrasi avicel PH 102 sebagai bahan penghancur, maka tingkat waktu hancur semakin cepat, kekerasan semakin turun, nilai kerapuhan semakin naik. Semakin tinggi konsentrasi pengisi, maka semakin lama waktu hancur yang dibutuhkan. Hasil analisis statistik dari ketiga formula yang diuji menunjukkan tidak adanya perbedaan yang signifikan antara waktu alir, kekerasan dan kerapuhan, sedangkan untuk uji waktu hancur menunjukkan adanya perbedaan yang signifikan (p?0.05).
Prioritizing Improvement Among Disadvantaged Students in Principle and in Practice
Authors: Joyce Kathryn E.
Published: July 2023

The US uses an evidence-based approach to education (US-EBE) as a strategy for pursuing two major goals: (1) to raise achievement in the US overall by facilitating improvement among all students, including students in disadvantaged groups; (2) to narrow achievement gaps between socially advantaged and disadvantaged groups by levelling up achievement among disadvantaged students. While both goals prioritize improvement among disadvantaged students in absolute terms, only the second attempts to address unequal achievement by prioritizing improvement among disadvantaged students relative to advantaged students. I argue that US-EBE can be reasonably expected to advance either the first goal or the second goal but not both simultaneously, as intended. This descriptive point raises a normative question: which goal should we pursue using US-EBE? I explore moral considerations that bear on this question, focusing on costs and benefits for students. I argue, provisionally, that we ought to use US-EBE to narrow gaps because the costs associated with doing so are morally justifiable whereas those associated with the alternative are not.
The Spatial Nature of Trust in Cosmopolitan Education
Authors: Hirose Yuzo
Published: July 2023

This paper investigates the core moment of cosmopolitan education by considering trust in education. Critical and postcolonial approaches recognize that dialogue plays a crucial role in cosmopolitan education. However, dialogue is not possible without sharing a fundamental platform. Trust could encourage us to construct this platform, and should thus be examined in an educational context. Previous studies on trust in education have mainly focused on the asymmetric relationship between educators and children, offering the impression that trust strengthens authoritarian order. However, in this paper I propose that trust in education needs to be recognized for containing a spatial and contextual nature, that is, a vertical trust between educators and children, and a horizontal trust especially between friends. Such spatial trust is based on trust in matters and therefore an open trust that embraces all matters in the world. This spatial trust could contribute to reinforcing cosmopolitan education, and furthermore, to formulating a post-anthropocentric cosmopolitan education.
The differentiation and integration of the hippocampal dorsoventral axis are controlled by two nuclear receptor genes
Authors: Yang Xiong , Wan Rong , Liu Zhiwen , Feng Su , Yang Jiaxin , Jing Naihe , Tang Ke
Published: July 2023

The hippocampus executes crucial functions from declarative memory to adaptive behaviors associated with cognition and emotion. However, the mechanisms of how morphogenesis and functions along the hippocampal dorsoventral axis are differentiated and integrated are still largely unclear. Here, we show that
COUP-TFI
and
-TFII
genes are distinctively expressed in the dorsal and ventral hippocampus, respectively. The loss of
COUP-TFII
results in ectopic CA1/CA3 domains in the ventral hippocampus. The deficiency of
COUP-TFI
leads to the failed specification of dorsal CA1, among which there are place cells. The deletion of both
COUP-TF
genes causes almost agenesis of the hippocampus with abnormalities of trisynaptic circuit and adult neurogenesis. Moreover,
COUP-TFI
/
-TFII
may cooperate to guarantee appropriate morphogenesis and function of the hippocampus by regulating the
Lhx5-Lhx2
axis. Our findings revealed a novel mechanism that
COUP-TFI
and
COUP-TFII
converge to govern the differentiation and integration of distinct characteristics of the hippocampus in mice.
Comparative analysis of two Caenorhabditis elegans kinesins KLP-6 and UNC-104 reveals common and distinct activation mechanisms in kinesin-3
Authors: Kita Tomoki , Chiba Kyoko , Wang Jiye , Nakagawa Atsushi , Niwa Shinsuke
Published: July 2023

Kinesin-3 is a family of microtubule-dependent motor proteins that transport various cargos within the cell. However, the mechanism underlying kinesin-3 activations remains elusive. In this study, we compared the biochemical properties of two
Caenorhabditis elegans
kinesin-3 family proteins, KLP-6 and UNC-104. Both KLP-6 and UNC-104 were predominantly monomeric in solution. As previously shown for UNC-104, non-processive KLP-6 monomer was converted to a processive motor when artificially dimerized. While it has long been thought that UNC-104 monomers do not have enough affinity to form homodimers, we found releasing the autoinhibition was sufficient to trigger dimerization of UNC-104 at nanomolar concentrations. In contrast, KLP-6 remained to be a non-processive monomer even when its autoinhibition was unlocked, suggesting a requirement of other factors for full activation. By examining the differences between KLP-6 and UNC-104, we identified a coiled-coil domain called CC2 that is required for the dimerization and processive movement of UNC-104. Our results suggest a common activation mechanism for kinesin-3 family members, while also highlighting their diversification.
The structural repertoire of Fusarium oxysporum f. sp. lycopersici effectors revealed by experimental and computational studies
Authors: Yu Daniel S. , Outram Megan A. , Smith Ashley , McCombe Carl L. , Khambalkar Pravin B. , Rima Sharmin A. , Sun Xizhe , Ma Lisong , Ericsson Daniel J. , Jones David A. , Williams Simon J.
Published: July 2023

Plant pathogens secrete proteins, known as effectors, that function in the apoplast or inside plant cells to promote virulence. Effector detection by cell-surface or cytosolic receptors results in the activation of defence pathways and plant immunity. Despite their importance, our general understanding of fungal effector function and detection by immunity receptors remains poor. One complication often associated with effectors is their high sequence diversity and lack of identifiable sequence motifs precluding prediction of structure or function. In recent years, several studies have demonstrated that fungal effectors can be grouped into structural classes, despite significant sequence variation and existence across taxonomic groups. Using protein x-ray crystallography, we identify a new structural class of effectors hidden within the secreted in xylem (SIX) effectors from
Fusarium oxysporum
f. sp.
lycopersici
(
Fol
). The recognised effectors Avr1 (SIX4) and Avr3 (SIX1) represent the founding members of the

Fol
d

ual-domain (FOLD) effector class, with members containing two distinct domains. Using AlphaFold2, we predicted the full SIX effector repertoire of
Fol
and show that SIX6 and SIX13 are also FOLD effectors, which we validated experimentally for SIX6. Based on structural prediction and comparisons, we show that FOLD effectors are present within three divisions of fungi and are expanded in pathogens and symbionts. Further structural comparisons demonstrate that
Fol
secretes a limited number of structurally related effectors during infection of tomato. This analysis also revealed a structural relationship between transcriptionally co-regulated effector pairs. We make use of the Avr1 structure to understand its recognition by the I receptor, which lead to disease resistance in tomato. This study represents an important advance in our understanding of
Fol
-tomato, and by extension plant-fungal interactions, which will assist the development of novel control and engineering strategies to combat plant pathogens.
Bioinspired Robust Helical‐Groove Spindle‐Knot Microfibers for Large‐Scale Water Collection
Authors: Wang Shaomin , Zhu Lingmei , Yu Dongdong , Han Xuefeng , Zhong Lieshuang , Hou Yongping , Zheng Yongmei
Published: July 2023

Helical structure is ubiquitous in nature with high‐order configuration, specific paths, large superficial areas, providing an approach to bioinspired wettability control. Owing to its special hydrophilic rough surfaces and periodic knot and joint structure, natural spider silk can catch tiny droplets in fog and transport them directionally, sparking scientific interest in bioinspired knotted microfibers to address the risk of water scarcity. To further enhance the water collection ability, a bioinspired helical‐groove‐modified spindle‐knot (HSK) microfiber is continuously fabricated in this work by a simple coating method combined with crack regulation. The formation and morphology can be precisely manipulated by adjusting the drawing velocity and concentration of the coating solution. Compared with smooth spindle‐knot microfibers, HSK exhibits greater performances of wetting speed, droplets growth rate, and hanging ability, which can be attributed to the unique helical paths that bring capillary force difference and offer extra three‐phase contact line lengths for water collection behavior. The maximum droplet volume is almost 2114 times that of the microfiber knots, which is the highest compared with previous reports. Moreover, HSK microfibers are endowed with repairable wettability, long‐term durability, excellent mechanical properties, and flexibility, showing great potential in the realm of applications for large‐scale water collection.
Synergistic Effect of Dual Surface Modified Ecoflex Polymer for Dynamic Triboelectric Nanogenerator Towards Sustainable Battery‐Free Tally Counter
Authors: Basith Sayyid Abdul , Chandrasekhar Arunkumar
Published: July 2023

Triboelectric nanogenerators (TENGs) scavenge electricity from low‐frequency mechanical motions. This study proposes a simple and cost‐effective method to synthesize a dual‐surface modified Ecoflex polymer (SME Sponge) with a porous inner structure and micro pyramidal projections on its surface. An Ecoflex‐Aluminum‐based contact separation triboelectric nanogenerator (EA‐CS TENG) is fabricated to investigate the impact of pores and micro pyramidal projections on triboelectric performance. The performances are evaluated with and without an air gap between the materials. Despite the gapless responses being lower than those with the air gap, the gapless system demonstrates the capability to charge a 0.1 µF capacitor up to 0.8 V with mechanical forces of 9 N, validating the potential of surface‐modified porous triboelectric materials for gapless TENGs. Additionally, the device with an air gap achieves a charge of 0.1 µF up to 3.3 V with mechanical forces of 9 N. Finally, a completely self‐powered tally counter is employed to verify the powering and sensing applications of EA‐CS TENG with an air gap. This study confirms the feasibility of utilizing low‐cost EA‐CS TENG as a renewable energy source for generating electricity from mechanical motions and driving devices without the need for batteries.
Exact and Computationally Robust Solutions for Cylindrical Magnets Systems with Programmable Magnetization
Authors: Masiero Federico , Sinibaldi Edoardo
Published: July 2023

Magnetic systems based on permanent magnets are receiving growing attention, in particular for micro/millirobotics and biomedical applications. Their design landscape is expanded by the possibility to program magnetization, yet enabling analytical results, crucial for containing computational costs, are lacking. The dipole approximation is systematically used (and often strained), because exact and computationally robust solutions are to be unveiled even for common geometries such as cylindrical magnets, which are ubiquitously used in fundamental research and applications. In this study, exact solutions are disclosed for magnetic field and gradient of a cylindrical magnet with generic uniform magnetization, which can be robustly computed everywhere within and outside the magnet, and directly extend to magnets systems of arbitrary complexity. Based on them, exact and computationally robust solutions are unveiled for force and torque between coaxial magnets. The obtained analytical solutions overstep the dipole approximation, thus filling a long‐standing gap, and offer strong computational gains versus numerical simulations (up to 106, for the considered test‐cases). Moreover, they bridge to a variety of applications, as illustrated through a compact magnets array that could be used to advance state‐of‐the‐art biomedical tools, by creating, based on programmable magnetization patterns, circumferential and helical force traps for magnetoresponsive diagnostic/therapeutic agents.
Barrier and passivation effects of 2D PANI@JNSs Janus nanosheets in epoxy anticorrosion coating
Authors: Zheng Yanyan , Chi Chongyi , Chen Denglong , Zeng Tuer , Zhang Yuxia , Lu Xiaoyu , Chen Qinhui
Published: July 2023

The filled sheet‐like inorganic materials can usually improve the anticorrosion performance of the coating. Herein, the Janus nanosheets (JNSs) with two‐dimensional structure were prepared by phase separation method, modified by polyaniline (PANI) on the amino side of JNSs and composited with epoxy resin (EP). Scanning electron microscope (SEM), transmission electron microscopy (TEM), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FT‐IR), thermogravimetry (TG) were used to characterize the morphology and chemical structure of JNSs and PANI@JNSs. The anti‐corrosion performance of coatings was measured by electrochemical impedance spectroscopy (EIS) and salt spray experiment. Compared with pure EP, the |Z|0.01Hz of 0.5%‐JNSs/EP coating and that of 0.5%‐PANI@JNSs/EP coating reached 5.6 × 108 and 5.4× 1010 Ω·cm2 after immersed for 35 days, nearly 2 and 4 orders of magnitude higher than pure EP respectively. The excellent anti‐corrosion performance of 0.5%‐PANI@JNSs/EP coating is due to the synergistic effect of physical barrier effect of PANI@JNSs, interfacial interaction between PANI@JNSs and epoxy resin and passivation effect of PANI. Moreover, PANI@JNSs possess both strengthening and toughening effects on composite coating. Janus nanosheets provide a new idea and method for preparing high‐performance anticorrosive materials.
Intense green light emission in Sr2ZnGe2O7:Mn2+ phosphors by the design of high symmetry melilite structure
Authors: Fang Yongzheng , Li Yuhang , Wang Chengze , Yin Wenxiang , Shi Tongna , Zhang Ganghua , Zhao Guoying , Zhou Xiaoping , Yang Jiexiang , Wu Dehua , Dong Langping , Hou Jingshan
Published: July 2023

A green phosphor Sr2ZnGe2O7:Mn2+ with a melilite structure was prepared using a high‐temperature solid‐state reaction. When the 535 nm emission was monitored, the excitation spectrum of the Sr2ZnGe2O7:Mn2+ was found to contain two excitation bands in the ultraviolet (UV) region. When excited by UV light, the sample shows bright green emission at 535 nm, which corresponds to the distinctive transition of Mn2+ (4T1→6A1). Moreover, the quantum efficiency of Sr2ZnGe2O7:Mn2+ could reach 67.6%. Finally, a high‐performance white‐light‐emitting diode (WLED) with a low correlated colour temperature of 4632 K and a high colour rendering index (CRI) of 92.3 were packaged by coating commercial blue and red phosphors with an optimized Sr2ZnGe2O7:Mn2+ sample on a 310 nm UV chip. This indicated that Sr2ZnGe2O7:Mn2+ has the potential application as a green component in the WLED lighting field.
Method validation, dissipation and residue status of fluopicolide and fosetyl‐aluminium in citrus using a rapid extraction method coupled with ultra‐performance liquid chromatography–tandem mass spectrometry
Authors: Litoriya Nitesh S. , Vaghela Kiran M. , Patel Mitesh R. , Parmar Kaushik D. , Chauhan Nirmal R. , Kalasariya Ravi L. , Chawla Suchi , Shah Paresh G.
Published: July 2023

The dissipation and residue status of a combination of fluopicolide and fosetyl‐aluminium (fosetyl‐Al) in citrus were evaluated in an experimental field. An efficient and sensitive liquid chromatography–tandem mass spectrometry, with rapid extraction, was carried out according to the SANTE guidelines. During the method validation, the recovery was within the range of 106.1–117.5, 94.4–115 and 85.4–109.5%, for fluopicolide, its metabolite 2,6‐dichlorobenzamide and fosetyl‐Al, respectively, with a relative standard deviation (RSD) of 0.3–10.6%. As a result, accuracy and precision at the spiking concentrations of 0.01, 0.05 and 0.10 mg/kg in citrus were within the acceptable range of 70–120% with an RSD of 20%. The amount of the deposits of fluopicolide, 2,6‐dichlorobenzamide and fosetyl‐Al was less than the limit of quantification (LOQ) at 0.01 mg/kg at 0 day, adhering to the application in standard [1.77 + 2.66 g of active ingredient (a.i.)/L] and double (3.54 + 5.32 g a.i./L) doses. The present study proposes that the utilisation of fluopicolide and fosetyl‐Al in citrus and the soil may not pose a health or environmental hazard provided that good agricultural practices are followed.
Accidentally discovered non‐communicating membranous ventricular septal aneurysm in a middle‐aged male patient
Authors: Abdelnabi Mahmoud , Almaghraby Abdallah , Saleh Yehia , Benjanuwattra Juthipong , Abdelgawad Hoda
Published: July 2023

Key Clinical Message

Membranous interventricular septal (MIVS) aneurysm is a rare often asymptomatic, accidentally discovered congenital anomaly, which might be complicated with right ventricular obstruction, rupture, thromboembolism, and conduction abnormalities.
The elusive cause of syncope: Left atrial myxoma with mitral valve obstruction
Authors: Haque Mahfujul Z. , Ahmed Muhammad , Mannan Abdul , Reesha Syeda , Husain Mashkur
Published: July 2023

Key Clinical Message

Syncopal patients should be evaluated for cardiac causes, including myxoma, as highlighted in this case. Transthoracic echocardiography and coronary angiography are valuable diagnostic tools. Interventional cardiology plays a crucial role in the successful treatment of myxoma.

This case video describes the presentation and successful treatment of a 58‐year‐old woman who experienced recurrent episodes of syncope. After ruling out other health concerns, a pulmonary embolism was suspected and further investigations revealed a mass in the left atrium causing significant obstruction of the mitral valve. The mass, identified as a neovascularized myxoma, was successfully resected, emphasizing the significance of considering myxoma as a potential cause of syncope and highlighting the role of interventional cardiology in its management.
Chemisches Recycling von Kunststoffen
Authors: Biessey Philip
Published: July 2023

No abstract.
Wasserstoff: Perspektiven der Nutzung in Energie, Verkehr und Chemie
Authors: Müller Karsten
Published: July 2023

In diesem Übersichtsartikel werden die wichtigsten Technologien zur Erzeugung, Speicherung und Nutzung von Wasserstoff vorgestellt. Für jeden der drei Schritte der Prozesskette stehen jeweils eine Reihe von technologischen Optionen zur Verfügung, die sich aber teilweise deutlich in ihrem Technologiereifegrad unterscheiden.
Unraveling the “ta‐da” moments of implementation in quality improvement
Authors: Park Ko Un , Weiss Anna
Published: July 2023

Plain Language Summary

This editorial explores the importance of developing surgeon‐level performance metrics and the use of implementation strategies for quality improvement.
Storytime, Audience to Authors: Enhancing Stakeholder Engagement
Authors: Brown Dale , Johnson Chamara , Ruggiero Allison , Gleckler William , McDonnell Devon , Simpson Denis
Published: July 2023

This paper is largely aimed at Public Agencies, such as Infrastructure and Transit authorities. The creation and development of projects at these agencies impacts multiple layers of stakeholders, who, in the collective experience of the authors, are often not involved in the project until the middle or end of the development phase or not until they have to use the system. These neglected end users and influencers of the system do not have a timely voice – they are effectively excluded.

This paper advocates for the early engagement of all defined stakeholders; the obvious and the unconventional, both internal and external to the agency. This paper does not provide a detailed ConOps process but rather defines what a ConOps is, why it is necessary, and at what stage in the project should one be developed. The principal conversation herein focuses on how to determine who the audience is for the system of interest (SOI) and ways to engage them. The paper describes a holistic approach to the creation and development of a ConOps deliverable by engaging the audience, who become stakeholders and effectively, authors. This paper concludes with a case study encompassing the discussion.
Benefits of Systems Engineering in Large Infrastructure Projects: the much‐anticipated empirical proof.
Authors: Ferrer Jaume Sanso , Rodríguez David Martín
Published: July 2023

Following successful deployment in the aerospace and automotive industries, the demand for a structured approach to Systems Engineering on large infrastructure projects is rapidly increasing in the current decade. However, there is still certain inertia on the part of some firms to adapt their processes within this engineering discipline, and hence an empirical demonstration of the benefits of systems engineering is needed. The purpose of this paper is twofold: on the one hand, it outlines an overall methodology to perform studies on Return on Investment of Systems Engineering (SE‐ROI) in large infrastructure engineering companies; on the other hand, this paper presents the results of this methodology applied to calculate the SE‐ROI in one such infrastructure engineering company.
Multilayer Network Models for Coordinating Orchestration of Systems Security Engineering
Authors: Williams Adam D. , Birch Gabriel C. , Caskey Susan A. , Fleming Elizabeth S.
Published: July 2023

Systems security engineering (SSE) faces new internal (e.g., increased digitization) and external (e.g., adversary capabilities) obstacles as systems increase in complexity and are deployed to increasingly challenging operating environments. Legacy approaches heavily rely on individual, physical, digital, or personnel domain‐specific strategies for security. Such segmented responses helped initiate efforts by the INCOSE systems security working group to identify fundamental elements of SSE. One of these fundamental elements is security orchestration, where the SSE goal is to coordinate between previously disparate security solutions. Multilayer network‐based approaches seemingly provide the logical structure and mathematical foundation to conduct security orchestration for “tightly coupled coordinated system defense in cyber‐relevant time.” Within multilayer networks, the ability to identify and manipulate cross‐domain (e.g., intralayer) connections that influence security performance measures demonstrates an enhanced level of security orchestration. As such, multilayer networks support the future of SSE efforts to mitigate real‐world complexities, innovative adversaries, and disruptive technologies. After describing security orchestration as a concept and foundational element, this paper explores how multilayer network models can enhance orchestration systems security engineering. Additionally, a demonstration case of systems security for a high consequence facility (as a complex system) is followed insights and implications for incorporating orchestration in the future of systems security.
An MBSE Architectural Framework for Inter‐Satellite Communication in a Multiorbit Disaggregated System
Authors: Anyanhun Awele , Adejokun Ademola Peter , Hause Matthew
Published: July 2023

The Multi‐Orbit Disaggregated System (MODS) concept is a disaggregation strategy geared towards improved resiliency and flexibility of space missions by dispersing payloads and/or functionality across multiple small satellites (SmallSats). Although SmallSats make good candidates for deployment as a MOD System, their success hinges on the ability to realize reliable Inter‐Satellite Communication (ISC). To this end, we investigate the efficacy of developing a model‐based systems engineering (MBSE) Architectural Framework for ISC to guide and constrain instantiations of ISC architecture solutions. An MBSE architectural framework is a systems engineering artifact that defines a set of views required to describe an architecture based on MBSE principles and practices. It provides a standardized structure and guidance to capture architectural decisions while maximizing opportunities for commonality, consistency, and interoperability within the Domain of Interest. To achieve well‐defined architecture descriptions, a MODS architectural framework pattern, and a comprehensive architectural framework for the ISC (sub)system are created and presented. The Systems Modeling Language (SysML) (OMG, 2019) serves as the modeling language for the framework design.