bluuebunny/crossref_metadata_2025 huggingface dataset:
Comprehensive Analysis of the Expression and Functions of Pattern Recognition Receptors in Differentiated Cytotrophoblasts Derived from Term Human Placentas
Authors: Motomura Kenichiro , Morita Hideaki , Okada Naoko , Matsuda Akio , Nakae Susumu , Fujieda Mikiya , Sago Haruhiko , Saito Hirohisa , Matsumoto Kenji
Published: April 2023

Pregnant women are exposed to various microbes, some of which can harm the mother and/or fetus and can lead to life-long morbidity and even death. The syncytiotrophoblast (STB) covers the placental villi and comes into direct contact with pathogens contained in the maternal blood and plays a key role in placental host defense. However, the precise mechanisms whereby the STB recognizes and responds to pathogenic microbes remain unclear. In this study, we comprehensively analyzed the expression of functional pattern recognition receptors, which are responsible for tissue defense against pathogens, in a primary STB model differentiated from highly purified human term cytotrophoblasts (CTBs). Screening for mRNA expression and multiplex cytokine/chemokine production demonstrated that differentiated CTBs (dCTBs) predominantly expressed dsRNA receptors, including TLR3, MDA5, and RIG-I. We confirmed that term human placentas also expressed TLR3. Transcriptome analysis revealed common and unique responses of dCTBs to a synthetic dsRNA (polyinosinic-polycytidylic acid) compared with human peripheral mononuclear cells. Moreover, polyinosinic-polycytidylic acid induced the release of type I and type III IFNs (IFN-β, IFN-λ1, IFN-λ2, IFN-λ3), as well as mRNA expression of IFN-stimulated genes (IFIT1, MX1, and OAS1). dCTBs underwent apoptosis via the mitochondrial pathway in response to dsRNA stimulation. These results suggest that dsRNA receptors expressed on the STB are key players in antiviral defense in the placenta. Elucidation of the underpinnings of these defense processes can help us better understand the pathophysiology of viral infections during pregnancy.
Table of Contents Vol 22, No 1 (2022)
Authors: Office Editorial
Published: April 2023

No abstract available.
Table of Contents Vol 11, No 1
Authors: Office Editorial
Published: April 2023

No abstract available.
Table of Contents Vol 45, No 1 (2022)
Authors: Office Editorial
Published: April 2023

No abstract available.
A professional nurse’s understanding of quality nursing care in Limpopo province, South Africa
Authors: Nyelisani Maggie , Makhado Lufuno , Luhalima Takalani
Published: April 2023

Background: Quality has increasingly become a critical part of life in every aspect. Patients are today continuously looking for good quality services from health professionals. Professional nurses are expected to render quality care to fulfil the patients’ healthcare needs. Poor nursing care has led to several litigations and the loss of patients’ lives. It is essential to explore professional nurses’ viewpoints regarding quality nursing care.Objectives: To explore and describe the understanding of professional nurses regarding quality care rendered to patients in the selected hospitals of Limpopo Province.Method: This study utilised a qualitative, exploratory-descriptive design. Individual semi-structured interviews were conducted for data collection. Participants comprised 35 professional nurses who were purposely selected. Data collected were audio-recorded and transcribed verbatim. Data were analysed using Tech’s eight-step data coding process, which led to the emergence of themes and sub-themes. Trustworthiness was ensured through credibility, confirmability, dependability, and transferability.Results: Three themes emerged: professional nurses’ descriptions, meanings, and expectations of quality nursing care. The findings highlight that quality nursing care means meeting patients’ needs through advocacy, empathy, fulfilment of patients’ needs, good interpersonal relationships and teamwork. Challenges experienced included the lack of resources and staff shortage.Conclusion: Hospital management needs to develop effective ways to support professional nurses in delivering quality nursing care. In discussion with the Department of Health (DoH), hospitals should be fully equipped with resources to render quality care to patients. Evaluation of service quality and patient satisfaction should be ongoing for improving the quality of patient care.Contribution: The study reveals that professional nurses perceive quality nursing care differently. Moreover, it emphasises the importance of maintaining and promoting quality nursing care as the cornerstone of healthcare.
Objective structured clinical examination: Do first-year nursing students perceive it to be stressful?
Authors: Adibone Emebigwine Dorothee Line , Linda Ntombizodwa S.B. , Martin Penelope
Published: April 2023

Background: The Objective Structured Clinical Examination (OSCE) is widely accepted as an effective means of assessing clinical competence and nursing skills. There is, however, little existing knowledge on how first-year nursing students perceived stress during their first OSCE.Objectives: To determine the perception of stress; to identify the perceived factors causing stress; and to determine the perceived incidence of stress.Method: A descriptive, survey was conducted on a sample of 82 first-year nursing students using the Perceived Stress Scale (PPS).Results: The results showed that more than half (n = 54) of students perceived stress at moderate levels. Students not having sufficient time to complete the OSCE was perceived as the main factor causing stress (mean = 22.04; standard deviation [s.d.] = 6.21). The correlation between perception of stress and perceived factors causing stress showed a significant weak positive linear correlation among the variables (r = 0.45; p  0.05).Conclusion: The study findings are important as the data determining the first-year nursing students’ perception of stress were collected immediately after their first OSCE, which may indicate that perception of stress was related to the actual event rather than the preparation for the OSCE. A follow-up qualitative research study should be conducted, preferably in the same setting, so that the students’ experiences of stress during the first OSCE can be explored in depth.
Table of Contents Vol 14, No 1 (2022)
Authors: Office Editorial
Published: April 2023

No abstract avalaible.
Table of Contents Vol 13, No 1 (2022)
Authors: Office Editorial
Published: April 2023

No abstract available.
Table of Contents Vol 69, No 1 (2022)
Authors: Office Editorial
Published: April 2023

No abstract available.
Human resource policies and work–life balance in higher education: Employee engagement as mediator
Authors: Opoku Felix K. , Kwao Isaac T. , Johnson Agyemang-Prempeh
Published: April 2023

Orientation: This article focuses on workplace policies, employee engagement and work–life balance in higher education.Research purpose: This study examined the mediation of employee engagement on the relationship between human resource (HR) policies and work–life balance among employees in the College of Distance Education (CODE) in Ghana.Motivation for the study: Although there is a plethora of research linking HR policies and employees’ work–life balance, the same cannot be said of the variables that mediate this relationship, as there are only few studies in that perspective.Research approach/design and method: The study adopted a purely quantitative approach, using the descriptive survey design. Data were collected from 232 staff of the CODE in Ghana. The Structural Equation Modelling was used to analyse the data.Main findings: The results indicated that employee engagement is a complementary partial mediator of the nexus between HR policies and work–life balance. It was also found that HR policies had a statistically significant effect on work–life balance.Practical/managerial implications: In order to effectively improve their staff’s work–life balance, management of the college must formulate policies that support employee engagement. Specifically, they can use flexible work arrangements, leave policy, and caretaking policies to positively influence their employees’ work engagement.Contribution/value-add: The results from this study offer a remarkable new knowledge that can be applied in promoting the work–life balance of employees in higher education.
Risk factors and predictors of adverse outcomes of in paediatric febrile neutropenia
Authors: Adekunle Motunrayo O. , Davidson Alan , Hendricks Marc
Published: April 2023

Background: Febrile neutropenia (FN) is the commonest acute complication of cancer treatment in children. The identification of patients at risk for FN as well as adverse outcomes has been described.Aim: To evaluate the prevalence and potential risk factors for FN and describe adverse outcomes in a cohort of children treated for cancer.Setting: The study was carried out in a paediatric oncology unit in a children’s hospital, Cape Town, South Africa.Methods: A retrospective study from 01 January 2017 to 31 December 2019 on children with cancer at Red Cross War Memorial Children’s Hospital, Cape Town, South Africa.Results: Two hundred and sixty-seven episodes of FN occurred in 179 patients. Independent predictors of FN were acute myeloid leukaemia (AML) (p = 0.039), acute lymphocytic leukaemia (ALL) (p = 0.020) and intensive chemotherapy (p ≤ 0.001). Mucositis (p = 0.001), central venous access device (CVAD) placement (p = 0.004), haematologic malignancies (p = 0.040), blood transfusion during FN episode (p  0.001) and severe neutropenia (white cell counts 0.3 × 109 cells/L) (p ≤ 0.001) were risk factors for adverse outcomes. The mortality rate from FN was 3.57%. Independent predictors of adverse outcomes in those with FN were AML (p = 0.001), CVAD placement (p = 0.019) and severe neutropenia (p = 0.005).Conclusion: Treatment related adverse outcomes following chemotherapy-induced FN are likely in children with AML, severe neutropenia and with CVAD placement.Contribution: Adverse outcomes from paediatric febrile neutropenia is high. There is need for clinical decision making aimed at prevention and early identification of individuals at risk.
Assessing the quest for miracles in Nigeria from the economic perspective
Authors: Ademiluka Solomon O.
Published: April 2023

In recent times, the quest for miracles among Nigerian Christians has become a social menace as many have fallen victim to fake miracle workers. The article studied the quest for miracles in Nigeria against the purpose and significance of miracles in the New Testament (NT), and sought to appraise this behaviour as a possible effect of the poor economic situation in the country. It applied the reader-oriented and descriptive methods. The work found that the manner of the quest for miracles by many Nigerian Christians indicates their lack of understanding of the essence of miracles in the NT. This wrong perception also explains the frantic efforts by some pentecostal preachers to work miracles, including commercialisation of miracles and certain occult practices. The essay concluded that Nigerian Christians wrong attitude towards miracles is an effect of the high rate of poverty in the country. The menace can, therefore, be ameliorated by addressing the economic situation. Government should change its corrupt attitude towards the economy while the church has to educate their members about the teaching of the Bible on miracles, and direct her preaching against corruption and its perpetrators.Contribution: The article is a contribution to the discourse on the controversies on miracles. It argues that Nigerian Christians’ perception of miracles contradicts the essence of miracles in the NT, and that this perception and the practices involved are an effect of the poor economic situation in the country.
Haematological Indices and Coagulation Profile as Predictors of Disease Severity and Associations with Clinical Outcome among COVID-19 Patients in Lagos, Nigeria
Authors: Kalejaiye Olufunto Olufela , Bolarinwa Abiola Bukunmi , Amaeshi Lemchukwu Chukwunonye , Ogamba Chibuzor Franklin , Nmadu Danladi Abraham , Sopekan Babajide Ayodeji , Akase Iorhen Ephraim
Published: April 2023

Background:

This study aims to evaluate the use of haematological indices and coagulation profiles as possible low-cost predictors of disease severity and their associations with clinical outcomes in COVID-19-hospitalized patients in Nigeria.

Materials and Methods:

We carried out a hospital-based descriptive 3-month observational longitudinal study of 58 COVID-19-positive adult patients admitted at the Lagos University Teaching Hospital, Lagos, Nigeria. We used a structured questionnaire to obtain the participants’ relevant sociodemographic and clinical data, including disease severity. Basic haematologic indices, their derivatives, and coagulation profile were obtained from patients’ blood samples. Receiver Operating Characteristic (ROC) analysis was used to compare these laboratory-based values with disease severity. A P < 0.05 was considered statistically significant.

Results:

The mean age of the patients was 54.4 ± 14.8 years. More than half of the participants were males (55.2%, n = 32) and most had at least one comorbidity (79.3%, n = 46). Significantly higher absolute neutrophil count (ANC), neutrophil–lymphocyte ratio (NLR), systemic immune-inflammation index (SII), lower absolute lymphocyte count (ALC) and lymphocyte–monocyte ratio (LMR) were associated with severe disease (P < 0.05). Patients’ hemoglobin concentration (P = 0.04), packed cell volume (P < 0.001), and mean cell hemoglobin concentration (P = 0.03) were also significantly associated with outcome. Receiver operating characteristic (ROC) analysis of disease severity was significant for the ANC, ALC, NLR, LMR, and SII. The coagulation profile did not show any significant associations with disease severity and outcomes in this study.

Conclusion:

Our findings identified haematological indices as possible low-cost predictors of disease severity in COVID-19 in Nigeria.
Preoperative Percutaneous Hamstring Tenotomy in a Patient with Severe Flexion Deformity Undergoing Primary Total Knee Replacement
Authors: Maitama Mohammed Inuwa , Alabi Ibrahim Abolaji
Published: April 2023

Fixed flexion deformity may accompany severe knee osteoarthritis in patients with long-standing pathology. This makes it difficult to achieve complete knee extension intraoperatively during total knee replacement surgery. Various options of treatment are available including preoperative serial knee extension and casting, intraoperative additional distal femoral resection to increase extension gap, and extensive soft tissue releases. We present this technique of on-table percutaneous medial hamstring tenotomy that we found helpful in achieving complete or near-complete knee extension intraoperatively, thereby minimizing the need for extensive bone resection and soft tissue dissection. An M is a 78-year-old man who presented with inability to walk for a 2-year duration due to pain and deformity of both knees. Complete clinical evaluation revealed the diagnosis of bilateral severe knee osteoarthritis with fixed flexion deformities. Ranges of knee motion were 90°–120° on the right and 80°–125° on the left. On-table percutaneous medial hamstring tenotomy + extension exercise under spinal anesthesia was carried out first and subsequently had posterior stabilized semi-constrained knee replacement. Knee extensions of 160° and 180° were achieved preoperatively after tenotomy and exercise and intraoperatively following distal cuts and soft tissue releases, respectively. This technique may be additive to various attempts at achieving adequate knee extension preoperatively for successful knee replacement. May be further evaluated to assess its effectiveness or otherwise to selected patients with severe flexion contractures undergoing primary total knee replacement.
The Effects of Consuming Almonds and Almond Oil on Blood Lipids
Authors: Osman Muhamed T. , Al-Naggar Redhwan Ahmed
Published: April 2023

Introduction:

Pharmacological approaches to hyperlipidemia are used in practice to lower lipids, but the benefits in lowering lipid levels also lead to some adverse effects. Therefore, the aim of this systematic review is to find out how almonds and almond oil affect blood lipids.

Methodology:

The studies in this systematic review were chosen systematically by searching Cochrane, PubMed, Scopus, Web of Science, and Embase from the earliest date to March 2021. Two authors independently screened titles and abstracts, followed by screening. Search strategy was conducted using the following keywords: Almond, Prunus, Prunus dulcis, amygdalus, oleum amygdalae, P. amygdalus, Prunus dulcis, Prunus amygdalus dulcis, and P. dulcis; human, person, subject, people, patient, participant, individual, volunteer, elder, senior, geriatric, women, men, adult, woman, and man; and LDL, Lipid, Lipid Profile, blood profile, HDL, Low Density Lipoprotein, TAG, Triglyceride, Triacylglycerol, High Density Lipoprotein, Cholesterol, Lipid regulation, TG Lipid Distribution, Total Cholesterol, Cholesterol, TC Lipid Distribution, cholesterol, total cholesterol, HDL-C, LDL, LDL-C, lipoprotein, hyperlipidaemia, hypercholesterolaemia, and hyperlipaemia.

Results:

Overall, the studies demonstrate a significant outcome of almond or almond oil on lowering blood lipid levels, except in three studies. We included 40 clinical trials. In all studies, the average daily intake of almonds was between 10 and 100 g/day. For almond oil, it was 500 ml of almond oil daily. The duration of almond consumption ranged from 3 to 30 weeks. Sample sizes in all strata ranged from 12 to 128 participants. In the 17 strata, subjects were described as generally healthy and in 5 strata as overweight or obese.

Conclusions:

Consuming almonds or almond oil has a significant effect on lowering lipids.
Effect of Neck Rehabilitation Exercise and Breathing Exercise on Visual Complaints in Individuals with Idiopathic Chronic Neck Pain
Authors: Abishek J R , Jeyaraj D Vincent
Published: April 2023

Background:

Neck pain is one of the most common musculoskeletal disorders and a leading cause of disability. Chronic neck pain causes hyperalgesia in soft tissues around the neck, and in severe cases, it leads to restriction of daily life activities. The excessive stress caused by the chronic pain leads to cervico-ocular gain, leading to a mismatch of reflexes that determine the gaze and vision. Chronic neck pain also alters the cervicothoracic kinematic change and length-tension changes in neck muscles and leads to decreased thoracic cage mobility. This leads to respiratory insufficiency in patients with chronic neck pain, which is similar to the changes that occur in cases of a neuromuscular disorder.

Objective:

The objective of this study was to find the effect of neck rehabilitation exercises and breathing exercises on visual complaints in individuals with idiopathic chronic neck pain.

Materials and Methods:

Thirty individuals with idiopathic chronic neck pain of both sexes ranging from 20 to 35 years were included according to the selection criteria and divided into two groups. Group A (n = 15) received the intervention for neck pain, whereas Group B (n = 15) did not receive any interventions.

Outcome Measures:

Neck disability Index, Visual Complain Index and NPRS are used as outcome measures.

Results:

Statistical analysis was done using SBM SPSS software version 20, which showed that there was a significant improvement in NDI in the experimental group (P < 0.05).

Conclusion:

This study concludes that there is a significant effect of neck rehabilitation exercises and breathing exercises on visual complaints in individuals with idiopathic chronic neck pain.
Subpulmonary membrane: A rare cause of right ventricular outflow tract obstruction
Authors: Gupta Rajat , Garg Garima , Mahant Tek Singh
Published: April 2023

Subpulmonary membrane is a rare cause of right ventricular outflow tract (RVOT) obstruction, and only a few case reports exist with or without associated ventricular septal defect. We report a series of three cases with subpulmonary membrane causing RVOT obstruction. Two of these have been operated (the first case operated after unsuccessful attempt at balloon dilatation), and the third case is on follow-up at present.
Innominate vein reconstruction in patients with bilateral superior vena cava undergoing bilateral bidirectional superior cavopulmonary anastomosis
Authors: Talwar Sachin , George Niwin , Firdaus Afroza , Fanai Mary H. , Choudhary Shiv Kumar
Published: April 2023

A 4.5-year-old patient with tricuspid atresia, pulmonary stenosis, bilateral superior vena cava veins with absent innominate vein, and hypoplasia of the left pulmonary artery required a bidirectional superior cavopulmonary anastomosis. An innominate vein was fashioned out of a 6 mm polytetrafluoroethylene graft. The technique is briefly discussed.
Successful balloon dilatation of an infolded polytetrafluoroethylene graft: An unusual cause of early Fontan failure
Authors: Gupta Saurabh Kumar , Mishra Sataroopa , Rajashekar Palleti , Kumar Sanjeev , Kothari Shyam Sunder
Published: April 2023

Despite optimal medical management, an 8-year-old boy had persistent pleural drainage following total cavopulmonary connection. Detailed evaluation, including computed tomography angiography, confirmed obstruction at the lower end of the circuit due to infolding of the polytetrafluoroethylene graft. Balloon dilation of the obstruction resulted in prompt resolution of pleural effusion with sustained relief at 1-year follow-up. The case demonstrates the importance of careful assessment in the diagnosis and successful nonsurgical management of an unusual cause of obstruction in the Fontan circuit.
Predictive performance of qSOFA in confirmed COVID-19 patients presenting to the emergency department
Authors: Heydari Farhad , Abbasi Saeed , Shirani Kiana , Zamani Majid , Masoumi Babak , Majidinejad Saeed , Nasr-Esfahani Mohammad , Sadeghi-Aliabadi Mahsa , Arbab Mohammadreza
Published: April 2023

ABSTRACT

Objectives:

It is critical to quickly and easily identify coronavirus disease 2019 (COVID-19) patients who become severely or even critically ill. Thus, this study was conducted to determine the accuracy of the quick Sequential Organ Failure Assessment (qSOFA) score in predicting the severity and mortality of COVID-19 patients.

Materials and Methods:

This was a prospective observational study of COVID-19 patients admitted to the emergency department (ED) between June 22, 2021, and November 21, 2021. The clinical characteristics of the participants were collected by the emergency physicians. The correlation of the qSOFA, Systemic Inflammatory Response Syndrome criteria (SIRS), Pneumonia Severity Index (PSI), and confusion, urea, respiratory rate, blood pressure, 65 years of age and older (CURB-65) scores for 14-day mortality were evaluated. The area under a receiver operating characteristic (AUROC) curve analysis was calculated to compare the effectiveness of qSOFA, SIRS, PSI, and CURB-65 to predict severe disease.

Results:

Eight hundred and ninety-four subjects were included. Of them, 721 patients (80.6%) survived after 14 days of admission. The mean age was 58.92 ± 17.80 years, and 551 subjects (61.6%) were male. Nonsurvived patients were significantly older (51.09 ± 23.60 vs. 38.10 ± 18.24, P = 0.004) and had more comorbidities (diabetes mellitus, respiratory, cardiovascular, and cerebrovascular disease) in comparison with survived patients. For COVID-19 mortality prediction, the AUROCs of qSOFA, CURB-65, PSI, and SIRS score were 0.799 (95% confidence interval [CI 0.771–0.825]), 0.829 (95% CI [0.803–0.853]), 0.830 (95% CI [0.804–0.854]), and 0.759 (95% CI [0.730–0.787]), respectively. All scores were good predictors of COVID-19 mortality.

Conclusion:

The qSOFA was more successful than SIRS in predicting mortality for COVID-19 patients and was similar to CURB-65 and PSI. Therefore, the qSOFA score can be considered a simple and rapid screening tool for identifying high-risk patients.
Health-Seeking Behavior Returning to Normalcy Overcoming COVID-19 Threat in Breast Cancer
Authors: Lee Eun-Gyeong , Han Yireh , Lee Dong-Eun , Moon Hyeong-Gon , Koh Hyoung Won , Kim Eun-Kyu , Jung So-Youn
Published: April 2023

Purpose The coronavirus disease 2019 (COVID-19) outbreak has significantly impacted the diagnosis and treatment of breast cancer. Our study investigated the change in diagnosis and treatment of breast cancer with the progress of COVID-19 pandemic.Materials and Methods The study group comprised 6,514 recently diagnosed breast cancer patients between January 1, 2019, and February 28, 2021. The patients were divided into two groups: pre–COVID-19 period (3,182; January 2019 to December 2019) and COVID-19 pandemic period (3,332; January 2020 to February 2021). Clinicopathological information related to the first treatment after breast cancer diagnosis was retrospectively collected and analyzed in the two groups.Results Among the 6,514 breast cancer patients, 3,182 were in the pre–COVID-19 period and 3,332 were in the COVID-19 pandemic period. According to our evaluation, the least breast cancer diagnosis (21.8%) was seen in the first quarter of 2020. The diagnosis increased gradually except for the fourth quarter in 2020. While early-stage breast cancer was diagnosed 1,601 (48.1%) during the COVID-19 pandemic (p=0.001), the number of surgical treatments increased 4.6% (p < 0.001), and the treatment time was slightly shorter 2 days (p=0.001). The breast cancer subtype distribution was not statistically different between the pre–COVID-19 and COVID-19 period groups.Conclusion In the early stages of the pandemic, the number of breast cancer cases temporarily decreased; however, they stabilized soon, and no significant differences could be identified in the diagnosis and treatment when compared to the period before the pandemic.
2020-2021 Reviewers
Authors: Hardy Hardy
Published: April 2023

Reviewer Acknowledgment
Extração assistida por ultrassom do óleo essencial da casca da laranja Pera Rio (Citrus sinensis)
Authors:   Centro Universitário Ingá – Uningá, Maringá, PR, Brasil., Silva Heloisa Almeida Montes , Pellogia Dyessica Santos ,   Centro Universitário Ingá – Uningá, Maringá, PR, Brasil., Vidal Nathalia Lohamy da Silva ,   Centro Universitário Ingá – Uningá, Maringá, PR, Brasil., Peixoto Juliana Luna  Bilheiro ,   Centro Universitário Ingá – Uningá, Maringá, PR, Brasil.
Published: April 2023

Citrus sinensis, conhecida popularmente como laranja, é a fruta cítrica mais produzida anualmente no mundo. Sua composição é de interesse para várias indústrias como perfumaria, cosméticos ou medicamentos, devido às propriedades benéficas para a saúde como antiobesidade, antidiabetes ou anticancerígena. Neste sentido, este trabalho teve como objetivo extrair o óleo essencial da casca de laranja Pêra Rio usando dois métodos distintos: hidrodestilação e ultrassom. A metodologia mais eficiente em termos de rendimento (peso/peso) foi o ultrassom alcançando 5,4%, na frequência de 80 Hertz, 40 °C por 30 minutos, enquanto a extração por Clevenger o rendimento foi de 0,32% em duas horas.
Impacto da pandemia da Covid-19 no rastreamento do câncer de colo uterino
Authors:   Universidade Estadual de Maringá - UEM, Maringá, PR, Brasil., Santos Lander dos , Pelloso Fernando Castilho ,   Fundação Estatal de Atenção à Saúde do Paraná – FEAS, Curitiba, PR, Brasil., Rosseto Rosana ,   Centro Universitário Ingá – Uningá, Maringá, PR, Brasil., Borghesan Deise Helena Pelloso ,   Centro Universitário Ingá – Uningá, Maringá, PR, Brasil., Carvalho Maria Dalva de Barros ,   Universidade Estadual de Maringá - UEM, Maringá, PR, Brasil., Pelloso Sandra Marisa ,   Universidade Estadual de Maringá - UEM, Maringá, PR, Brasil.
Published: April 2023

O objetivo foi comparar os dados relacionados à realização do rastreamento do câncer de colo de útero no período anterior ao início da pandemia no Brasil, com os resultados durante e após a pandemia. Estudo observacional sobre número de rastreamento realizados nos serviços públicos de saúde entre janeiro e dezembro dos anos de 2018 a 2021. Os dados foram obtidos no Sistema de Informação DATASUS. Os resultados mostram queda importante do rastreamento durante a pandemia. Este cenário exige um olhar minucioso sobre as mulheres uma vez que o resultado da falta de rastreamento não é evidenciado a curto prazo e sim a longo prazo.
Impacto da pandemia de Covid-19 nos tratamentos ortodônticos
Authors:   Centro Universitário Ingá – Uningá, Maringá, PR, Brasil., Stroppa Lorena Caroline , Anhani Gabriela ,   Centro Universitário Ingá – Uningá, Maringá, PR, Brasil., Peloso Renan Morais ,   Centro Universitário Ingá – Uningá, Maringá, PR, Brasil., Pinzan-Vercelino Célia Regina Maio ,   Centro Universitário Ingá – Uningá, Maringá, PR, Brasil., Silva Paula Patrícia Cotrin da ,   Centro Universitário Ingá – Uningá, Maringá, PR, Brasil., Freitas Karina Maria Salvatore de ,   Centro Universitário Ingá – Uningá, Maringá, PR, Brasil.
Published: April 2023

O estudo analisou o impacto da pandemia de Covid-19 nos tratamentos ortodônticos. Um questionário Google Forms foi enviado aos pacientes ortodônticos de diversas clínicas via WhatsApp. O questionário foi respondido por 104 pacientes com média de idade de 30,45 anos (dp=14,53). Dos pacientes, 31,7% declarou ter o tratamento ortodôntico interrompido em algum momento durante a pandemia, com tempo médio de 2 meses. Do total de pacientes, 29,8% não compareceu às consultas, por apresentarem sintomas de Covid-19 (46,2%) e por não quererem correr o risco de contaminação (35,3%); 31,7% declarou que a pandemia atrapalhou seu tratamento ortodôntico.
Incidência de infecção urinária em crianças na comunidade nos últimos dois anos na cidade de Maringá, PR, Brasil
Authors:   Centro Universitário Ingá – Uningá, Maringá, PR, Brasil., Ermino Karina Tiemi , Pellogia Dyessica Santos ,   Centro Universitário Ingá – Uningá, Maringá, PR, Brasil., Santos Letícia Carniato Jorge dos ,   Centro Universitário Ingá – Uningá, Maringá, PR, Brasil., Moreno Vanessa Generale ,   Centro Universitário Ingá – Uningá, Maringá, PR, Brasil., Romanichen Francine Maery Dias Ferreira- ,   Centro Universitário Ingá – Uningá, Maringá, PR, Brasil.
Published: April 2023

A Infecção do Trato Urinário (ITU) é uma doença causada pela multiplicação de microrganismos patogênicos em qualquer segmento do trato urinário. Este trabalho tem como objetivo avaliar a incidência de Infecção do Trato Urinário em crianças com idade de 0 a 12 anos, e os principais microrganismos causadores da infecção. Trata-se de uma pesquisa quantitativa e descritiva, realizada com dados coletados no Laboratório Central de Análises Clínicas da Prefeitura. Obteve-se um total de 505 amostras, no qual 11,48% foram positivas e 88,52% negativas. Contudo, 75,86% das amostras foram do sexo feminino e 24,14% masculino. Entre as bactérias mais prevalentes nas ITU houve um predomínio da Escherichia coli.
Influência da escovação com dentifrícios de diferentes abrasividades na cor de cerâmicas de silicato de lítio com zircônia
Authors:   Centro Universitário Ingá – Uningá, Maringá, PR, Brasil., Colauto Gabriel Nichele , Ferruzzi Fernanda ,   Centro Universitário Ingá – Uningá, Maringá, PR, Brasil., Pini Nubia Inocencya Pavesi ,   Centro Universitário Ingá – Uningá, Maringá, PR, Brasil., Neto Daniel Sundfeld ,   Centro Universitário Ingá – Uningá, Maringá, PR, Brasil., Hespanhol Hermes Carvalho ,   Centro Universitário Ingá – Uningá, Maringá, PR, Brasil., Merino Bruna Gabriela ,   Centro Universitário Ingá – Uningá, Maringá, PR, Brasil.
Published: April 2023

O estudo avalia os efeitos da escovação com dentifrícios de diferentes abrasividades sobre a cor de cerâmicas de dissilicato de lítio. Foram produzidos 21 espécimes de cerâmica, seccionados e polidos. Posteriormente, os espécimes foram divididos em grupos e submetidos a protocolos de escovação dentária simulada, sendo que o grupo controle foi escovado com água destilada, o grupo C com o dentifrício Colgate Whitening e o grupo E com o dentifrício Elmex Sensitive. A avaliação da cor foi realizada com espectrofotômetro EasyShade em dois momentos distintos: antes e após a escovação simulada e por final feito uma média.
Levantamento epidemiológico sobre diabetes em Maringá e o entendimento da doença pelo paciente a partir da orientação do médico
Authors:   Centro Universitário Ingá – Uningá, Maringá, PR, Brasil., Marques Natiele Ilucenski , Corsi Lorena Gervásio ,   Centro Universitário Ingá – Uningá, Maringá, PR, Brasil., Costa Rafael Bezerra Dalla ,   Universidade Estadual de Maringá - UEM, Maringá, PR, Brasil., Barrena Helenton Cristhian ,   Centro Universitário Ingá – Uningá, Maringá, PR, Brasil.
Published: April 2023

O diabetes mellitus é um distúrbio metabólico crônico, caracterizado por hiperglicemia. A pesquisa foi realizada através de um formulário online, compartilhado nas redes sociais, com o objetivo de verificar o nível de entendimento da doença pelo paciente e avaliar o grau de satisfação em relação às orientações recebidas. Foram obtidas 23 respostas de residentes de Maringá, sendo a maioria (56,7%) diabéticos do tipo 2. Com relação ao entendimento dos pacientes, 39,1% afirmaram que esse se deve apenas às explicações do médico, 21,7% se deve apenas às pesquisas realizadas na internet e 34,8% a ambos. A maioria mostrou-se satisfeita com o atendimento médico.
Determination of optimal plant growth regulators for breaking seed dormancy and micropropagation of Sorbus aucuparia L.
Authors: Dinçer Deryanur
Published: April 2023

Sorbus aucuparia L. is an important forest tree used in the reforestation of high-altitude mountainous areas, which carries significant pharmaceutical, industrial, ornamental, food, and ecological properties. However, the seed propagation and micropropagation of mature trees of S. aucuparia L., presents various difficulties which are integral aspects for the re-propagation and breeding of novel cultivars. In this study, we isolated the mature embryo-containing seeds of selected varieties of S. aucuparia L. from their seed coat and used them directly as explants in vitro to investigate and determine the optimal dose of cytokinin in breaking seed dormancy and micropropagation. 3 mg/L of benzyl adenine (BA) in addition to different concentrations and combinations of kinetin (0.5, 1, and 2 mg/L), indole-3-butyric acid (IBA) (0, 1, 0.5, and 1 mg/L), and 1-naphthalene acetic acid (NAA) (0, 1, 0.5, and 1 mg/L) were applied within a Murashige and Skoog (1962) (MS) medium at germination inhibition, shoot elongation, and shoot proliferation. In the MS mediums containing BA and kinetin, germination was achieved at the end of 1 week, and shoot proliferation was achieved at the end of 3 weeks. The most successful germination (96%), tallest shoot length (mean 5.1 cm), most shoot proliferation (mean 7.2 pieces), and number of nodes (mean 9.7 pieces) were identified in the MS containing 3 mg/L BA and 1 mg/L kinetin. Direct root formation with shoot elongation occurred in 25% of explants which germinated in the MS medium. For shoots propagated without roots in this medium, 62% of these achieved rooting at the highest dose of 1 mg/L indole-3-acetic acid (IAA) using a two-stage rooting method. Rooted shoots were successfully transferred to an ex vitro medium. These results provide a basis for breaking seed dormancy of selected Sorbus L. genotypes quicker, leading to more effective clonal production.
Keywords: Sorbus aucuparia L., rowanberry, tissue culture, seed dormancy, micropropagation, in vitro
De la filosofía del lenguaje a la filosofía política del siglo XXI
Authors: Nagua-Jiménez Luis Felipe , Moreno-Morán Douglas Xavier , Jumbo-Balcázar Germania Lorena
Published: April 2023

En el presente artículo de investigación, se tiene como objetivo reflexionar acerca de la transición de la filosofía del lenguaje a la filosofía política del siglo XXI. Para ello, se maneja un diseño cualitativo con alcance descriptivo, además se trata de una investigación documental. Es menester plantear estas consideraciones dedicadas a estudiar la lengua como inherente al hombre, en el entendido como hombre referido a la especie humana y la política, como dedicada a establecer una sociedad de carácter honesto y equitativa para cada miembro e integrante de la misma, así como la filosofía política observada en la Constitución nacional de 2008. La conclusión que resalta consiste que en cada época la filosofía se comprometió a tutelar a las formas de gobierno existentes o proponer un cambio, en búsqueda de una mejor sociedad, en el Ecuador debe tener presente al sumak kawsay, pues promulga procura equilibrar al hombre y a la naturaleza, en discordancia con la visión de solo cuidar el ambiente y naturaleza, por ser necesarios para la humanidad y no por derecho propio, como lo merece; de igual manera se plantea una definición del término filosofía.
Feminism as a gender condition for global bioethics
Authors: Vargas-Machado Camilo Andrés , Vargas Sepúlveda Claudia Faviola
Published: April 2023

With the objective of corresponding the political and social movement of feminism with the bioethical discipline, a systematic review of literature produced and generated in the Spanish, English and Portuguese languages in the period from 1970 to 2021 was carried out. With exploration in search engines and databases. Of virtual data, where a qualitative method was applied, with a descriptive approach, with the design of a review matrix instrument to apply a correlational method, from which two emerging categories were determined: complex thinking and neo-atheism. As a result of the review, it was concluded that feminism is a mass movement of a different nature, which germinated from the current defending the will and self-determination of women, whose theory has adapted to the changes in the situation that has allowed it to accept more equitable positions, to break patriarcal schemes where global bioethics has changed, supported by the theories of complex thought and neo-atheism, to invigorate its critical-revisionist nature and framed to produce changes, they will be recorded in the everyday reality.
Centralidade intraurbana, permanências e transformações espaciais em Montes Claros/MG
Authors: França Iara Soares de
Published: April 2023

Este artigo analisa a recente dinâmica da área central de Montes Claros/MG e a centralidade que nela se configura como forma espacial e relevante papel que exerce na articulação das diferentes partes do conjunto do tecido urbano. A análise tem como base a Teoria das Localidades Centrais ou da Centralidade/TLC, de cunho urbano e regional, desenvolvida pelo geógrafo alemão Walter Christaller. Isto posto, apresenta um breve diagnóstico, mapeamento atual da área de estudo e registros iconográficos analisados por meio de abordagem quali-quantitava.O recorte espacial escolhido na estrutura interna distingue-se dos demais setores da cidade em razão da elevada concentração, diversidade e especialização de atividades. A análise mostrou mudanças na estruturação da cidade, constatou-se que a atual dinâmica presente na área central de Montes Claros produz dialeticamente permanências e transformações nessa cidade média, daí a redefinição da centralidade intraurbana. Como desdobramento, no plano interurbano, Montes Claros figura-se historicamente como um centro de atração para os municípios de sua região geográfica consolidando interações espaciais cada vez mais complexas
How Do Arts Contribute to Educational Research? A Book Review of Arts-Based Research in Education: Foundations for Practice
Authors: Dahal Niroj
Published: April 2023

I write this review as a recommendation for potential readers: those who are new to and veterans with respect to arts-based research. Arts-Based Research in Education: Foundations for Practice is edited by Melisa Cahnmann-Taylor and Richard Siegesmund, with contributions from 22 authors and a cover artist. In addition to providing some information from a usual structure around contents, central themes and concepts, intended audience, genres of writing styles, strengths and weaknesses, and uniquenesses, I primarily focus on the content of the chapter entitled “Four guiding principles for arts-based research practice” which I found extraordinarily significant in the second edition of this book and most meaningful for those planning their arts-based research projects.
“Research Is Not Innocent”: A Review of Thalia Mulvihill and Raji Swaminathan’s Collaborative Qualitative Research
Authors: Wulff Daniel
Published: April 2023

Mulvihill and Swaminathan have written a wide-ranging book that takes a close look at how qualitative research can be collaborative and what implications come from how collaborative practices are taken up. While taking an appreciative stance toward collaborative research practices, they do not shy away from the challenges and unrealized potentials that are involved. This book serves as both an introduction to the basics of collaborative qualitative research and an in-depth look at the issues for the more experienced collaborative researcher.
The Challenges of Educating Children in Low-Income Contexts: A Book Review of Learner-Centred Pedagogy in the Global South Pupils and Teachers’ Experience
Authors: Marlina Reni , Hamdani Hamdani
Published: April 2023

Learner-Centred Pedagogy in the Global South: Pupils and Teachers' Experience, published by Routledge in 2022 is a book written by Nozomi Sakata. The purpose of writing this book review is to guide readers through a case-based and mixed methods investigation of Learner-Centred Pedagogy (LCP) implementation in the global South, which has primarily been investigated through qualitative methodologies. This book can shed further light on the connection between students' learning attitudes and their academic achievement, particularly those of low-income students. This book serves as a link between early education, which was still founded on culture, and modern education, which is rife with political philosophy, especially in low-income communities.
KINETICS OF THE REACTION OF AN ARYLIDENE 2-THIOHYDANTOIN DERIVATIVE WITH SOME Pd(II) COMPLEXES
Authors:   University of Kragujevac, Institute for Information Technologies, Serbia, Stanić Petar , Ašanin Darko ,   University of Kragujevac, Institute for Information Technologies, Serbia, Vasić Marijana ,   Academy of Professional Studies Šumadija, Department in Kruševac, Serbia, Soldatović Tanja ,   State University of Novi Pazar, Department of Chemical Technological Sciences, Serbia, Šmit Biljana ,   University of Kragujevac, Institute for Information Technologies, Serbia
Published: April 2023

Reactions of 3-(benzylideneamino)-2-thioxoimidazolidin-4-one with some palladium complexes (PdCl2, Pd(DMSO)2Cl2 and K2PdCl4) were monitored with NMR spectroscopy, which is used as a convenient and practical tool for determining the kinetic parameters of the reactions. Rate constants of the reactions were determined and reactivity of the complexes towards the 2-thiohydantoin derivative was compared.
THE INFLUENCE OF THE ENOLOGICAL TANNINS APPLICATION ON THE PHENOLIC COMPOSITION OF WINE
Authors:   University of Belgrade, Faculty of Agriculture, Serbia, Petrovic Aleksandar , Lisov Nikolina ,   University of Belgrade, Faculty of Agriculture, Serbia, Plavsic-Janjatovic Ivana ,   University of Belgrade, Faculty of Agriculture, Serbia, Sredovic-Ignjatovic Ivana ,   University of Belgrade, Faculty of Agriculture, Serbia, Mitrovic Danka ,   University of Belgrade, Faculty of Agriculture, Serbia
Published: April 2023

The chemical composition of wine depends on the degree of maturity and quality of the grapes, as well as the agroecological conditions under which the grapes are grown. Tannins are of particular importance for wines, they are the source of the characteristic astringency of red wines. The main aim of this study was to investigate the influence of addition of enological tannins (0.05 g/L; 0.15 g/L; 0.3 g/L) on the phenolic composition of wine. The effect of the addition of differenttannins on the certain phenolic compounds (gallic acid, caffeic acid, ellagic acid and quercetin) was measured by HPLC analysis.Only forcontent of gallic and caffeic acid, there was a statistically significant difference between the control sample and all other samples with added tannins.
UPTAKE OF HEAVY METALS BY ALFALFA (Medicago sativa L.): POT EXPERIMENT
Authors:   University of Niš, Faculty of Sciences and Mathematics, Serbia, Mitov Denis , Petrović Stefan ,   University of Niš, Faculty of Sciences and Mathematics, Serbia, Ranđelović Aleksandar ,   University of Niš, Faculty of Sciences and Mathematics, Serbia, Mrmošanin Jelena ,   University of Niš, Faculty of Sciences and Mathematics, Serbia, Pavlović Aleksandra ,   University of Niš, Faculty of Sciences and Mathematics, Serbia, Tošić Snežana ,   University of Niš, Faculty of Sciences and Mathematics, Serbia
Published: April 2023

In this work, the uptake of some heavy metals (Cd, Cr, Cu, Ni and Pb) by alfalfa (Medicago sativa L.) was studied in a pot experiment. Alfalfa and soil samples were prepared by wet digestion and analyzed by ICP-OES. The obtained results were discussed based on the determined concentrations, translocation factors (TFs) and enrichment factors (EFs) values, showing that this plant species is able to uptake increased amounts of Cd by roots.
UPTAKE OF HEAVY METALS BY WHEAT (Triticum aestivum L.): POT EXPERIMENT
Authors:   University of Niš, Faculty of Sciences and Mathematics, Serbia, Mitov Denis , Petrović Stefan ,   University of Niš, Faculty of Sciences and Mathematics, Serbia, Đorđević Nikola ,   University of Niš, Faculty of Sciences and Mathematics, Serbia, Mrmošanin Jelena ,   University of Niš, Faculty of Sciences and Mathematics, Serbia, Pavlović Aleksandra ,   University of Niš, Faculty of Sciences and Mathematics, Serbia, Tošić Snežana ,   University of Niš, Faculty of Sciences and Mathematics, Serbia
Published: April 2023

In the present work, the uptake of some heavy metals by wheat grown on soils artificialcontaminated with Cd, Cr, Cu,Ni and Pb individually and in combination,was studied in a pot experiments. The samples were prepared by wet digestion and analyzed by ICP-OES and the obtained results were discussed based on the values of the obtained concentrations, enrichment factors (EFs) and translocation factors (TFs).
PENINGKATAN HASIL BELAJAR SISWA PADA POKOK BAHASAN IKATAN KIMIA DENGAN MENGGUNAKAN MODEL PEMBELAJARAN SINEKTIK
Authors: Gultom Fransiskus , Hernawaty Hernawaty , Karo-karo Selamat
Published: April 2023

Penelitian ini bertujuan untuk mengetahui hasil belajar kimia siswa dengan menggunakan model pembelajaran Sinektik di SMA Swasta Jambi Medan. Populasi dalam penelitian adalah seluruh siswa kelas X SMA Swasta Jambi Medan yang terdiri dari 2 kelas. Sampel diambil secara acak berjumlah 2 kelas yang terdiri dari kelas eksperimen dan kelas kontrol. Data yang diamati adalah hasil belajar kimia siswa, yang dikumpulkan melalui tes pilihan berganda sebanyak 30 soal yang terdiri dari 5 opsi jawaban, yang sebelumnya telah diujicobakan validitas, reliabilitas, tingkat kesukaran dan daya pembeda tes. Data yang diperoleh dianalisis dengan uji t, dimana sebelumnya telah diuji normalitas dan homogenitas data. Hasil belajar kelas eksperimen rata-rata pretest (27,81 ± 7,21) dan rata-rata posttest (76,88 ± 5,70) dengan peningkatan hasil belajar Gain sebesar 68% sedangkan hasil belajar kelas kontrol rata-rata pretest (22,03 ± 6,70) dan rata-rata posttest (70,47 ± 6,00) dengan peningkatan hasil belajar Gain sebesar 62%. Uji hipotesis dilakukan pada taraf signifikansi α = 0,05 menggunakan uji-t satu pihak yaitu pihak kanan dimana thitung > ttabel (3,05 > 1,667139), yang berarti Ho ditolak dan Ha diterima. Dengan melihat hasil penelitian tersebut dapat disimpulkan bahwa hasil belajar kimia siswa yang diberi perlakuan melalui penerapan model pembelajaran Sinektik lebih tinggi daripada menggunakan pengajaran konvensional.