bluuebunny/crossref_metadata_2025 huggingface dataset:
Accelerated Antibacterial Inactivation on 2D Cu-Titania Surfaces: Latest Developments and Critical Issues
Authors: Rtimi Sami , Kiwi John , Pulgarin Cesar
Published: September 2016

This review focuses on Cu/TiO2 sequentially and Cu-TiO2 co-sputtered catalytic/photocatalytic surfaces leading to bacterial inactivation discussing their stability, synthesis, adhesion and antibacterial kinetics. The intervention of TiO2, Cu and the synergic effect of Cu and TiO2 on films prepared by a colloidal approach and other techniques is also reviewed leading to bacterial inactivation. Processes in aerobic media and anaerobic media leading to bacterial loss of viability on multidrug resistant (MDR) pathogens, Gram-negative (-) and Gram-positive(+) bacteria are described. Insight is provided for the interfacial charge transfer mechanism under solar irradiation occurring between TiO2 and Cu. surface properties of 2D TiO2/Cu and TiO2-Cu films are correlated with the bacterial inactivation kinetics observed in the dark and under light. The intervention of these antibacterial sputtered surfaces in health-care facilities leading to MRSA-isolates is described in the dark and under the actinic light. The synergic intervention of the Cu and TiO2 films leading to bacterial inactivation prepared by direct current magnetron sputtering (DCMS), pulsed direct current magnetron sputtering (DCMSP) and highly ionized pulse plasma magnetron sputtering (HIPIMS) is reported in a detailed way.
Influencia de la actividad física acuática sobre el neurodesarrollo de los bebés: revisión sistemática
Authors: Latorre García Julio , Sánchez-López Antonio Manuel , Baena García Laura , Noack Segovia Jessica Pamela , Aguilar-Cordero María José
Published: September 2016

Introducción: la actividad física en bebés mediante terapia acuática es ampliamente conocida para el posterior desarrollo de las áreas sensoriales, cognitivas y motoras. De este modo, el bebé tendrá mayor sensación de libertad, placer y recuerdo del útero materno. Además, el margen de seguridad terapéutico en el agua es muy amplio, lo que permite un desarrollo óptimo de programas de estimulación temprana acuática.Objetivo: llevar a cabo una revisión sistemática de la literatura científica sobre el ejercicio físico en el agua y su influencia en el neurodesarrollo de los bebés.Métodos: se ha efectuado una búsqueda sistemática mediante el modelo PRISMA. La búsqueda de los artículos de la presente revisión se realizó en las bases de datos a través de Scopus y PubMed, así como en la plataforma Web of Science (WOS) y en webs oficiales de organismos internacionales, como la Organización Mundial de la Salud (OMS/WHO). La revisión se efectuó entre los meses de mayo y noviembre del año 2015.Resultados: se incluyen un total de 14 artículos que cumplen los criterios de inclusión. La realización de ejercicios acuáticos en bebés tiene más beneficios que riesgos. No existe un aumento de enfermedades infecciosas, respiratorias o alérgicas. Por el contrario, se describen efectos beneficiosos en el ámbito social, mayor apego con los padres y efectos positivos en la movilidad, coordinación y velocidad de reacción ante los estímulos. El agua supone un medio adecuado para el tratamiento de niños con diversidad funcional, ya que reduce la espasticidad y permite realizar movimientos más amplios que en el medio terrestre.Conclusiones: la metodología empleada en los estudios incluidos en la presente revisión es diversa. Los bebés que realizan actividad física en el agua ven aumentadas su movilidad funcional, coordinación y sociabilización, tanto con los padres como con otros bebés presentes en el grupo de intervención. Algunos estudios señalan que los ejercicios acuáticos promueven mejoras en el neurodesarrollo.
Consumo de alcohol en adultos de Monterrey: relación con actividad físico-deportiva y familia
Authors: Ruiz-Juan Francisco , Isorna-Folgar Manuel , Vaquero-Cristóbal Raquel , Ruiz-Risueño Jorge
Published: September 2016

Objetivo: determinar la relación entre práctica físico-deportiva y consumo de alcohol en adultos mexicanos en función de una serie de variables sociodemográficas y la influencia de la familia.Material y métodos: 1.008 mexicanos fueron entrevistados mediante cuestionario por rutas aleatorias. Se utilizó una regresión logística multinomial para calcular odds ratio (OR) e intervalo de confianza (IC = 95%).Resultados: el consumo de alcohol de alto riesgo alcanza al 12,7% de la población, siendo muy superior el consumo en los hombres respecto a las mujeres. Por edades el consumo es superior entre los 18 y 45 años. A mayor nivel de estudios mayor probabilidad de consumir alcohol frecuentemente y menor de consumirlo en grandes cantidades. No hay una relación clara entre la práctica de ejercicio físico y el consumo de alcohol. Se ha encontrado que los que practican modalidades deportivas colectivas y/o recreacionales presentan un mayor consumo de alcohol. El contexto familiar constituye un factor de riesgo, siendo hermanos y padres los más influyentes. El consumo de tabaco está ligado de forma significativa al consumo de alcohol. Conclusiones: se encuentran diferencias en el consumo de alcohol en cantidad y/o en frecuencia en función del sexo, la edad, el nivel de estudios, el contexto familiar y la práctica de ejercicio físico. Los resultados de este estudio son de gran utilidad, ya que ponen de manifiesto el efecto que la práctica físico-deportiva y el entorno socioafectivo poseen en la adquisición y regulación de conductas saludables o nocivas.
Beneficios inmunológicos de la leche humana para la madre y el niño. Revisión sistemática
Authors: Aguilar Cordero María José , Baena García Laura , Sánchez López Antonio Manuel , Guisado Barrilao Rafael , Hermoso Rodríguez Rafael , Mur Villar Norma
Published: September 2016

Introducción: la leche es un fluido cambiante formado por lípidos, proteínas, minerales y moléculas inmunes. Las tasas de lactancia materna (LM) exclusiva se encuentran por debajo de los objetivos fijados por la Organización Mundial de la Salud (OMS), que establece que las madres deben dar el pecho de forma exclusiva durante 6 meses y suplementarla con otros alimentos durante los dos primeros años. Si se llevan a cabo esas recomendaciones, las madres y sus bebés se verían beneficiados. La leche materna modifica su composición en función de la edad del bebé, el momento del día, la dieta materna o el grado de plenitud de la glándula mamaria. Estudios recientes apuntan que existe una relación dinámica entre el estado de salud del niño y la composición de la leche de la madre, ya que, incluso, aumenta la producción de anticuerpos ante una infección activa del lactante.Objetivo: efectuar una revisión sistemática de la literatura científica a base de reunir los conocimientos actuales relacionados con las propiedades inmunológicas de la lactancia materna y de sus efectos en la salud de la madre y el niño.Métodos: se lleva a cabo una búsqueda sistemática y se seleccionan 21 artículos específicos sobre el tema, siguiendo las directrices PRISMA.Resultados: los estudios analizados muestran que la leche materna tiene gran cantidad de componentes inmunológicos que aumentan ante las necesidades del bebé. También ofrece beneficios físicos y psicológicos para la madre y el niño y supone, igualmente, un ahorro económico al disminuir los ingresos hospitalarios de los bebés, puesto que disminuye su morbilidad. Conclusiones: los bebés alimentados con leche materna tienen menos probabilidades de padecer enfermedades gastrointestinales, respiratorias, alérgicas o asma, y también previene la obesidad infantil. Además, la LM tiene efectos beneficiosos para la madre, pues disminuye el riesgo de padecer cáncer de mama, enfermedades cardiovasculares y el síndrome metabólico. Se deben aumentar las tasas de lactancia materna exclusiva, al menos hasta los 6 meses de vida.
Voidage Replacement Ratio as a Decision Variable in Closed Loop Reservoir Management Process Improving Field Production Efficiency
Authors: Nogueira Elysio Mendes
Published: September 2016

Closed Loop Reservoir Management (CLRM) aims to automate the classic reservoir management process by means of using artificial intelligence, control theory and optimization workflows. One of the tasks performed during a CLRM is the optimization process which deals with defining the best allocation of resources so as to maximize, for instance, Net Present Value. This resource allocation may be wells location, injection (or production) rate for each well, etc.

In this context, the goal of this paper is to introduce an innovative approach of CLRM for optimization of waterflooding process by using Voidage Replacement Ratio (VRR) as a decision variable to generate optimum NPV of a given field. It is argued that this decision should be taken prior to any definition on well injection rates or either zone injection rate for Intelligent Wells.

A simplified oil-water reservoir model is used to simulate real field behavior under a number different scenarios of VRR values defined by an optimization algorithm designed to reach maximum value of a simplified NPV function. From that initial model, three case studies are performed to answer three questions: How can different reservoir and economic scenarios impact decision of the optimum value of VRR to be pursued by reservoir managers?;How to adapt the proposed method to different development project drivers?Is it possible to improve field's performance by defining an optimum sequence of variation for VRR through time?

This paper demonstrates that, although being the most common practice for waterflooding projects, a strategy of keeping VRR ~ 1 do not always lead to optimal profitability in terms of NPV. They are also discussed the many aspects to be considered when deciding on the pressure management strategy for developing a reservoir safely and economically while limited by technical and operational constraints.

The studies performed demonstrate how an active VRR management during production lifetime might generate improved efficiency of company's assets aligned to its development strategy. Also, a reliable rule of thumbs guideline is presented to give operators a qualitative insight on how different geological and economic scenarios might impact on the definition of optimum strategy for VRR management.
New Method of Steam Channeling Plugging in Horizontal Wells of Heavy Oil Steam Stimulation
Authors: Yu Haiyang , Li Liangchuan , Zheng Jiapeng , Ji Wenjuan , Qin Xiaoping , Fu Xiaopo , Gao Wenming
Published: September 2016

An effective plugging method is proposed for the purpose of solving the problem of steam channeling in the steam stimulation horizontal wells when the steam injection pressure is close to the critical pressure of boiler. The method is successfully applied to several wells in the field. The core of the technology is the original method for calculating the volume of steam channeling, the new plugging agent system and the dam type sealing channeling process. Based on the well logging data, well temperature curve and inters well connectivity, the original method for calculating the volume of steam channeling is determined by theoretical calculation. A new low cost and high temperature resistant agent system has been developed by experiment. The dam type sealing technology is established according to 3D model experiment and numerical simulation.

The results show that the probability of occurrence of steam channeling is significantly increased when the permeability difference is greater than 4. The location of steam channeling is high permeability layer and small well spacing. The original calculation method of steam channeling volume can accurately predict the dosage of the plugging agent.

The new low cost and high temperature resistant agent system is a solution system without solid particles, which is based on inorganic materials, organic materials as the inducing agent and surfactant as the stabilizer. The viscosity is about 3mPa.s at room temperature. The system begins to solidify at 80°C and forms the bulk solid state finally. The system can be able to bear 350°C, and the residual resistance coefficient is as high as 30.

The technical core of the dam type sealing technology is the alternate combination of high strength slug and weak strength slug. The role of the high strength slug is sealing of the steam channeling while the role of the weak strength slug is adjusting the subsequent injection pressure. The total dosage of plugging agent is 0.4 times of the volume of steam channeling. According to the intensity of steam channeling and the size of steam injection pressure, the high strength slug is 1/3~1/2 times of the dosage of the total blocking agent. The high permeability layer is not only the steam channeling, but also the flow passage of crude oil. The high permeability layer is not completely blocked, so the yield of the subsequent crude oil is not affected. The dam type sealing technology can effectively control the subsequent injection pressure, and does not affect the crude oil production.

The advantage of this technology is effective steam channeling plugging, suitable injection pressure and high yield of crude oil, and this technology has very important significance for the exploitation of heavy oil steam stimulation.
Optimization and Adaptation of Wastewater Treatment Plants WWTP Located in Camps of Oil & Gas Operations in Peruvian Jungle
Authors: Centurión Mario , Alosilla Luis
Published: September 2016

It was identified that the original design of the Wastewater Treatment Plant (WWTP) to be implemented in the different projects of Block 57 only includes an aerobic biological process followed by a process of sedimentation and disinfection in two complementary consecutive stages, designed to comply the Water Quality Limits (LMP) according the Ministry of Environment regulations for effluent from domestic wastewater treatment plants, DS 003-2010-Minam. Since four years ago, oil and gas companies are regulated in terms of effluents by D.S. No. 037-2008-PCM: Maximum Permissible Limits of Liquid Effluent by Oil&Gas Industry, being more demanding on water quality parameters. For this reason, it is presented this study: Techniques for Optimization and Adaptation of Wastewater Treatment Plants (WWTP) adapting the plants to meet effluents regulations, also due to temporary increase of users, short term projects, presence of compounds of nitrogen and phosphorus in the water. The optimization includes controlling the aerobic biological process with operational changes by adjusting the concentration of dissolved oxygen to remove the ammoniacal nitrogen and purification of organic matter by biological means using the primary settling tank as anoxic process, the elimination of total phosphorus by testing dosage metal salts such as aluminum sulfate and ferric chloride to produce an ion exchange to remove the total phosphorus and operational improvements including a treatment system and sludge drying.
Effectiveness in Heavy Oil Wells Cleaning at Boscan Field With Cyclone Bailer and Coiled Tubing Unit
Authors: Leal Wendy , Rodriguez Maria , Chirinos Florelia , Mustone Carlos , Mogollon Gustavo , Vilchez Zulay , Rodriguez Marianh , Arteaga Francisco , Pirela Henrut
Published: September 2016

The obstructions generated by elastomers is one of the most common problems in the majority of the heavy oil fields producing with progressive cavity pump (PCP) in Venezuela. For this reason rehabilitation work are done constantly to clean wells with the objective of reactivating, or increasing their production.

Given that the application of conventional rehabilitation work done with service rig using wash pipe and shoe mill has not shown successful results because of lack of circulation in the well; arises the need for a new cleaning technique by using the cyclone bailer tool combined with coiled tubing unit.

The global procedure of this combination involve making runs with coiled tubing and the cleaning's BHA composed of: a shoe mill, collecting chamber, a flapper valve, a bottom filter, a high torque bottom motor, and a cyclone bailer which allows, by a suction effect, catching the residuals inside the collecting chamber. Once the collecting chamber is filled with elastomers and oil residuals, the tool is taken to surface for cleaning and this process is repeated until reaching the target depth and remove all obstruction.

As a consequence of applying this technique on the four wells studied, an average overall effectiveness of 85% was achieved in clearing blockages ranging from 363-817 ft in liners from 3-1/2 to 6-5/8 in, in an average of 8 runs in 7 days operational time per job, thereby achieving full production restoration at 769 BPD, which meant an average increase of 22% above the estimated production of 630 BPD.

The result of the application of the cyclone bailer tool to remove the cumulated rubber residuals in the liner showed more effective than cleaning with jets, or conventional motors with wicks used previously, this is due to compaction and the sizes of the elastomers residuals, which in several occasions reached up to 1.5 feets in length, too big to pass by annular space between inner diameter of liner and outer diameter of coiled tubing (CT) and the debris were too heavy to be lifted using fluids energized with nitrogen.

It is important to highlight that during the first run of well intervention with this technology, no further progress was observed due to flapper valve obstruction in the BHA due to the presence of large pieces of trapped elastomer, which prevented entry of other elastomers in the collecting chamber, making it difficult to reach full capacity and thereby causing lost time in the recovery of elastomers and well cleaning, so it was decided to try changing the BHA eliminating the flapper valve to allow free passage of elastomeric rubber clippings and so achieve greater debris collection by run, thus obtaining better results in the operation, due to their compaction and maintaining a low fluid pumping rate while pulling the CT to surface to prevent their return to the well.
Insidie nella confezione di un cloze mirato. Appunti a partire dall’osservazione di cloze morfolessicali della certificazione di italiano per stranieri CELI
Authors: Torresan Paolo
Published: September 2016

L’indagine che conduciamo ha per oggetto due cloze morfolessicali inclusi nella Prova di Competenza Linguistica di livello B2 della certificazione di italiano come lingua straniera CELI dell’Università di Stranieri di Perugia, sessione estiva 2007 (CVCL, 2007a). I cloze sono analizzati nei loro diversi elementi: le istruzioni, il punteggio, il testo, i singoli item (vale a dire le espunzioni che il candidato è tenuto a integrare). L’analisi di alcune criticità consente di avviare un ragionamento ampio sulle insidie che la confezione di un cloze, sia in sede di testing che nella normale prassi didattica, può comportare.
INVESTIGATION OF THE PROCESSES OF BIODEGRADA-TION OF SORTED MUNICIPAL SOLID WASTE IN LAND-FILL REACTOR
Authors: Pitak Inna , Shaporev Valery , Novozhylova Tetiana , Nechyporenko Dmytro
Published: September 2016

The article describes methods to intensify the processes of biodegradation. The results of the investigations of waste biodegradation process modeling of waste and the intensification of these processes are given. Generalized mathematical model of emission of biogas at the landfill is developed and methods of process intensification in the body of the landfill are proved. As a result of research, microbiological and biochemical processes in the body of the landfill are analyzed, the main factors affecting the intensity of the processes are revealed and their impact is analyzed. It was concluded that the landfill is a biochemical reactor, where interrelated heat and mass transfer processes occur in the dense bed through which the gas is filtered and internal sources of heat. It was developed a complete mathematical model allowing estimating based on the equations of material and heat balances, the rate of biogas reactor. A model and calculation method for the analysis of heat and mass transfer processes in a dense bed with internal heat sources and to calculate the emission of biogas at design and operation of the landfill-reactor were given. Possible ways of intensifying the process of biodegradation in the reactor were revealed on the basis of analysis of the equations of the mathematical model describing the process in the reactor and the theory of microbiological processes of this class.
MANUFACTURE OF TWO-LAYERS AND DOUBLE-SIDED IRON CASTINGS WITH DIFFERENTIAL STRUCTURE AND PROPERTIES
Authors: Fesenko Kateryna , Mogylatenko Volodymir , Fesenko Anatoliy , Kosyachkov Vyacheslav , Fesenko Maksym
Published: September 2016

The paper proposes a new method of production of bilayer and double-sided castings with differentiated structure and properties using the technology of in-mold modification of the initial melt, smelted in a single melting furnace, which ensures formation of hard wear-resistant white iron as the working layer, and formation of ductile shock-resistant cast iron with nodular graphite as the core or the mounting part. Numerous laboratory studies confirm the feasibility of the proposed method and provide conditions ensuring differentiation of structure and properties in local parts or layers of castings. The prospects of the method for manufacturing a wide range of industrial castings are indicated.
CAPABILITIES TO VISUALIZE THE OPERATING REGION OF SURGICAL INTERVENTION RELATIVELY TO CRANIAL LANDMARKS FOR NEURONAVIGATION
Authors: Avrunin Oleg , Tymkovych Maksym , Kononenko Tetiana
Published: September 2016

During the work we analyze the process of neuronavigation in terms of using different approaches for aligning the operational volume at surgical stage in respective to the preplanning data. The work is dedicated to capabilities to visualize the operating region of surgical intervention relatively to cranial landmarks for neuronavigation.

We analyzed the principles of selection of anatomical landmarks. We give practical advice on the choice of anatomical landmarks with respect to system of image analysis. Based on processes of image analysis and image processing we show necessity of utilization specialized anatomical landmarks. At this research we propose utilize the cranial landmarks on outer edge of cranium.

It was confirmed the possibility of their automated determination. Was shown the necessity of intracerebral landmarks binding to the cranial landmarks.

The proposed approach to selection of anatomical landmarks can be applied in neuronavigation for simplification process of their extraction and their calculation.
THREE-DIMENSIONAL COMPUTER MODELLING AND STRESS-STRAIN ANALYSIS OF TEMPOROMANDIBULAR JOINT
Authors: Palyvoda Roman , Malanchuk Vladyslav , Kryschuk Mykola , Volovar Oksana
Published: September 2016

The main purpose of the study is to build 3D model of temporomandibular joint and mandible using programs for modelling and design, research stress and strain in cartilage and bone of model depending on different contraction of chewing muscles (especially lateral pterygoid muscle). There were used such methods as computer tomography data, finite element method and analysis topography of lateral pterygoid muscle on cadavers. In results of study was obtained maximal stress in anterior and distal parts of articular disc between 1,4–3 MPa and 0,4–1 MPa. Thus, static loads of articular disc were different, depends on force of contraction lateral pterygoid muscle. Muscle disturbances (hyperfunctioning, atrophy etc.) should be considered in treatment of temporomandibular dysfunction and examined on magnetic resonance investigation if it is present in the same patient.
DENTAL STATUS OF CHILDREN WITH THE TEETH FORMATION DISORDERS
Authors: Liubarets Svetlana
Published: September 2016

Aim of research: to analyze the dental status of children with the teeth formation disorders on the background of the digestive diseases (DD). Object of research – the change of the teeth hard tissues and periodontal tissues, subject of research – clinical characteristics of the status of teeth hard tissues and periodontal ones. Results of research: in children with chronological enamel hypoplasia (CEH) and molar-incisor hypomineralization (MIH) on the background of digestive diseases (Class ICD-10, К00-К93: “Gastritis and duodenitis” (К29), “Cholecystitis” (К81), “Other bile-excreting diseases” (К83)) was fixed the high and very high intensity of the dental caries, respectively. Caries as CEH and MIH complication was diagnosed in 55,81 % and 42,85 % of examined, respectively. In children with CEH and MIH on the background of digestive organ diseases was diagnosed the middle severity of gingivitis РМА, Papillary, Marginal, Alveolar Indices): 29,13±8,87 % and 25,24±8,97 %, respectively. The rate of persons with the healthy periodontal tissues according to CPI (Community Periodontal Index) was 21,42±21,91 % in children with CEH and 7,14±13,11 % in examined with MIH. In examined with CEH and MIH was fixed the satisfactory hygiene of the oral cavity according to Green-Vermillion index (OHI – Oral Hygiene Index). Conclusion: children with teeth hard tissues formation disorders on the background of digestive diseases need the dispensary observation and course of the therapeutic and prophylactic arrangements for preventing the possible complications (caries, gingivitis, periodontitis).
Genetic Mutations in Acute Myeloid Leukemia
Authors: Blau Ol'ga Vladimirovna
Published: September 2016

Acute myeloid leukemia (AML) is a clonal malignancy characterized by ineffective hematopoiesis. Most AML patients present different cytogenetic and molecular defects associated with certain biologic and clinical features of the disease. Approximately 50-60 % of de novo AML and 80-95 % of secondary AML patients demonstrate chromosomal aberrations. Structural chromosomal aberrations are the most common cytogenetic abnormalities in about of 40 % of de novo AML patients. A relatively large group of intermediate risk patients with cytogenetically normal (CN) AML demonstrates a variety of outcomes. Current AML prognostic classifications include only some mutations with known prognostic value, namely NPM1, FLT3 and C/EBPa. Patients with NPM1 mutation, but without FLT3-ITD or C/EBPa mutations have a favorable prognosis, whereas patients with FLT3-ITD mutation have a poor prognosis. A new class of mutations affecting genes responsible for epigenetic mechanisms of genome regulations, namely for DNA methylation and histone modification, was found recently. Among them, mutations in genes DNMT3A, IDH1/2, TET2 and some others are the most well-studied mutations to date. A number of studies demonstrated an unfavorable prognostic effect of the DNMT3A mutation in AML. The prognostic significance of the IDH1/2 gene is still unclear. The prognosis is affected by a number of biological factors, including those associated with cytogenetic aberrations and other mutations, especially FLT3 and NPM1. The number of studies of genetic mutations in AML keeps growing. The data on genetic aberrations in AML obtained to date confirm their role in the onset and development of the disease.
Allogeneic Hematopoietic Stem Cell Transplantation in Acute Myeloid Leukemias: Prognostic Significance of Complex Karyotype Including del(5q), -7, del(7q) Abnormalities
Authors: Gindina Tat'yana Leonidovna , Mamaev N.N. , Bondarenko S.N. , Nikolaeva E.S. , Petrova I.A. , Slesarchuk O.A. , Borovkova A.S. , Razumova S.V. , Alyanskii A.L. , Zubarovskaya L.S. , Afanas'ev B.V.
Published: September 2016

Aim. To evaluate the prognostic significance of the complex karyotype including del(5q), -7, del(7q) abnormalities in acute myeloid leukemia (AML) after allogeneic hematopoietic stem cell transplantation (allo-HSCT). Materials & Methods. Forty-four AML patients with chromosome 5 and/or 7 abnormalities (22 women and 22 men, aged from 1.2 to 67 years, median 31.2 years) were examined. Analysis of overall (OS) and event-free survival (EFS) predictors after allo-HSCT in patients with different clinical, transplant and cytogenetic characteristics was performed. Results. Prior to allo-HSCT, the complex karyotype (with three or more chromosomal abnormalities) was observed in 19 (43 %) patients, the monosomal karyotype was in 8 (18 %) patients. Univariate analysis demonstrated that OS and EFS differed in patients from different age groups (> 18 vs. < 18 years; p = 0.01 and p = 0.05, respectively), with different disease status at transplantation (1 remission vs. other clinical status; p = 0.1 and p = 0.008, respectively), with and without complex karyotype (СК- vs. CK+; p = 0.05 and p = 0.002, respectively), with and without monosomal karyotype (МК- vs. MK+; p = 0.009, only for EFS), and with different stem cells source (bone marrow vs. other source; p = 0.03 only for OS). Multivariate analysis confirmed that age of 18 years and more (p = 0.02 and p = 0.01, respectively), active disease at allo-HSCT (p = 0.04 and p = 0.005, respectively), complex karyotype (p = 0.04 и p = 0.0008, respectively) and stem cell source other than bone marrow (p = 0.02 only for OS) were independent predictors of OS and EFS deterioration. Conclusion. The study demonstrates that chromosome 5 and/or 7 abnormalities as a part of the complex karyotype is high-risk factor in AML patients undergoing allo-HSCT (unlike the monosomal karyotype), that requires the special therapeutic approach.
Allogeneic Hematopoietic Stem Cell Transplantation in Myelofibrosis
Authors: Barabanshchikova M.V. , Morozova E.V. , Baykov V.V. , Barkhatov I.M. , Mamaev N.N. , Bondarenko S.N. , Alyanskii A.L. , Zubarovskaya Lyudmila Stepanovna , Afanas'ev B.V.
Published: September 2016

Background & Aims. At present, the allogeneic hematopoietic stem cell transplantation (allo-HSCT) is the only treatment option with curative potential in patients with myelofibrosis (MF), especially in intermediate and high risk categories. The aim of the study is to perform a retrospective analysis of alloHSCT outcomes in MF patients. Materials & Methods. Outcomes of allo-HSCT in 11 intermediate-2 (n = 3) and high (n = 6) risk patients (based on Dynamic International Prognostic Scoring Scale, DIPSSplus) performed in the R.M. Gorbacheva Scientific Research Institute of Pediatric Hematology and Transplantation over the period from 2005 till 2015 were analyzed in the study. Two more patients underwent allo-HSCT in MF blast phase. Two patients received ruxolitinib before allo-HSCT and 1 patient before and after allo-HSCT. Reduced intensity conditioning regimen was used in all cases. Results. Primary engraftment was documented in 8 patients. 72 % of patients achieved complete hematological remission. Molecular remission and myelofibrosis regression were confirmed in 5 patients. 5 of 11 patients were still with remission and followed-up by the date of the paper submission. The overall two-year survival was 46 %. Conclusion. Allo-HSCT is an effective treatment option for MF patients. Further trials are required to evaluate an optimal timing for allo-HSCT in MF patients and efficacy of Janus kinase (JAK) inhibitors as pre- and posttransplant therapy in MF.
Evaluating the effect of accruals quality, investments anomaly and quality of risk on risk premium (return) of stock of listed companies in Tehran Stock Exchange
Authors: Kazem Ebrahimi Seyed , Bahrami Nasab Ali , Karim Mehdi
Published: September 2016

Nowadays, reaching to economic goals in any society requires public participation, which is only the result of people participation. Investment in stock market is one of people participation methods. So, awareness from stock return and its affecting factors is one of anxieties of investors and owners of shares. In this research, authors evaluate the effective factors on stock return using Fama and French models. So, authors study the effect of some factors including accruals quality, anomalies of investments, size factor, market’s risk premium factor, and book equity to market equity factor, on stock’s risk premium which is representative of stock returns, in 70 listed companies in Tehran stock exchange from 20 March 2003 to 20 March 2014. Results showed that accruals quality and quality of risk have meaningful effect on risk premium, which is representative of stock returns. Results also show that investment anomaly has no meaningful effect on risk premium and, consequently, on stock returns.
Keywords: accruals quality, investments anomaly, risk premium, return diversity, stock returns, quality of earnings, discretionary accruals, systematic risk. JEL Classification: M41, G12, G14
The relationship between organizational citizenship behavior and organizational performance (case study: Agricultural Jihad Organization of Mazandaran Province)
Authors: Sadeghi Ghasem , Ahmadi Masoud , Taghvaee Yazdi Maryam
Published: September 2016

The main purpose of this study is analyzing the relationship between organizational citizenship behavior and market orientation. This study is an applied research in terms of the purpose based on a descriptive correlational method. The statistical population included all employees of Agricultural Jihad Organization of Mazandaran province consisting of 1923 persons. 391 people (male and female) were selected using random stratified sample. Data were collected through two standard questionnaires: Podsakoff’s (2003) organizational citizenship behavior (24 questions) and Fazel’s (2012) organizational performance (13 questions). Validity of questionnaires was confirmed by experts and reliability of them was confirmed using Cronbach’s coefficient alphabet. Cronbach’s alpha for the organizational citizenship behavior and organizational performance was calculated by 0.80 and 0.87. Components of organizational citizenship behavior included civic virtue, altruism, conscientiousness, sportsmanship, and courtesy. Components of organizational performance included customer satisfaction, employee satisfaction, organizational effectiveness, and financial results and the market. Data were analyzed using descriptive and inferential statistics through SPSS software. The descriptive statistics included frequency, percentage, mean, and standard deviation and inferential statistics included Kolmogorov-Smirnov, Spearman’s rank correlation coefficient, Fisher’s z-distribution using SPSS software.
Keywords: organizational citizenship behavior, employees, organizational performance, Agricultural Jihad, Mazandaran Province. JEL Classification: D23, M12, M10
An evaluation of the links between quality of reporting and efficiency of investment in companies listed at Tehran Stock Exchange
Authors: Hayati Keyvan , Sedaghat Parastoo
Published: September 2016

This paper aims to evaluate the relationship between the quality of reporting and efficiency of investment in companies registered at Tehran Stock Exchange Market during 2010-2014 (Iranian calendar) period. The population consists of manufacturing firms registered at Tehran Stock Exchange and the statistical sample includes 126 companies. To explore the assumptions of the research, secondary data, as well as audited balance sheets have been used to collect the data. The data have been analyzed using descriptive and inferential methods at two levels and via Panel Yapold tests. Reliability for variables has been verified using Luin, Leen and Chu methods for data related to the study. The results coming out of the study have been obtained by financial and monetary data of the companies registered at Tehran Stock Exchange during the years between 2010 and 2014 and have been analyzed. It was illustrated that not only companies that used higher qualities of reporting had better investments, but also the higher quality of reporting itself made the investments more efficient. Moreover, the results showed that there is negative and significant relation between too much investment and quality of financial reporting and between too little investment and the quality of reporting.
Keywords: quality of reporting, investment efficiency, Tehran Stock Exchange. JEL Classification: M41, M42, G32
O potencial formativo do Pibid pela perspectiva dos formadores de professores
Authors: Massena Elisa Prestes , Cunha Maria Isabel da
Published: September 2016

Este trabalho apresenta o potencial formativo a partir da experiência no Pibid, do ponto de vista de concepções e práticas, de formadores de professores atuantes no citado programa e em cursos de Licenciatura em Biologia, em Física e em Matemática, oriundos de três instituições de ensino superior do Sul do Brasil. Foram realizadas entrevistas semiestruturadas com nove docentes. Os dados, analisados à luz da Análise Textual Discursiva, apontam para o fato de que a experiência no interior do Pibid auxilia a repensar o currículo dos cursos de licenciatura nessas instituições, aproximando os docentes da realidade escolar e possibilitando o aprofundamento de temáticas que impactam a formação dos licenciandos. O estudo sinaliza também que ainda não é clara, para os formadores, a relação entre as contribuições do programa e seu desenvolvimento profissional docente.
Políticas e práticas contemporâneas sobre relações raciais e a pós-graduação
Authors: Batista da Silva Marcos Antonio
Published: September 2016

O presente artigo tem como objetivo revisar temas relacionados a relações raciais e à pós-graduação na sociedade brasileira, com base em três eixos temáticos: políticas de ação afirmativa; trajetórias e mobilidade educacional na pós-graduação; e a pós-graduação, planos e metas. Este estudo, situado no campo da Psicologia Social, serviu de revisão de literatura como base para o desenvolvimento de pesquisa sobre trajetórias de estudantes negros de pós-graduação na sociedade brasileira.
IMPLEMENTASI SISTEM PENJAMINAN MUTU INTERNAL SEBAGAI UPAYA MENINGKATKAN MUTU PENDIDIKAN DI UNIVERSITAS GADJAH MADA
Authors: Sulaiman Ahmad , Wibowo Udik Budi
Published: September 2016

Penelitian ini bertujuan untuk menggambarkan implementasi Sistem Penjaminan Mutu Internal (SPMI) sebagai upaya meningkatkan mutu pendidikan di Universitas Gadjah Mada. Studi ini merupakan penelitian kualitatif dengan metode studi kasus. Penelitian dilakukan di Universitas Gadjah Mada, dengan subjek Kantor Jaminan Mutu (KJM UGM). Teknik pengumpulan data: observasi langsung, penelusuran dokumen dan arsip, serta wawancara. Hasil penelitian menunjukkan: (1) Kebijakan dan konsep SPMI berupa dokumen akademik dan dokumen mutu disusun oleh KJM UGM; (2) KJM UGM sebagai koordinator dalam merencanakan dan melaksanakan SPMI di seluruh universitas; (3) Implementasi SPMI dilaksanakan dengan penyusunan rancangan berupa Siklus SPMI; (4) Kendala yang dihadapi: komitmen pimpinan, jumlah tenaga auditor, kegiatan SPMI menjadi rutinitas; (5) Langkah yang ditempuh: menyediakan tenaga expert penjaminan mutu, pelatihan auditor, membangun semangat penjaminan mutu; (6) Evaluasi Implementasi SPMI dilaksanakan setiap tahun; (7) Pemanfaatan hasil implementasi SPMI: membangun budaya mutu, akreditasi dan sertifikasi nasional dan internasional; dan (8) Pengembangan implementasi SPMI mengacu pada manajemen mutu ISO dan standar BAN PT.
PROFIL GURU SMK TEKNIK PEMESINAN DAN RELEVANSINYA DENGAN KURIKULUM PRODI PENDIDIKAN TEKNIK MESIN FT UNY
Authors: Surono Surono , Wagiran Wagiran
Published: September 2016

Penelitian ini bertujuan untuk mengungkapkan: (1) profil ideal guru SMK Kompetensi Keahlian Teknik Pemesinan (KKTP), (2) relevansi profil ideal guru SMK-KKTP dengan kurikulum Prodi PTM FT UNY, (3) proses pembelajaran di Prodi PTM FT UNY, dan (4) profil calon guru SMK-KKTP. Penelitian ini adalah penelitian kuantitatif dengan metode survei, yang dilakukan di Prodi PTM FT UNY dan sebelas SMK di provinsi DIY. Teknik pengumpulan data yang digunakan adalah dokumentasi dan angket. Teknik analisis data yang digunakan adalah analisis statistik deskriptif. Hasil penelitian adalah sebagai berikut. (1) Profil ideal guru SMK-KKTP terdiri dari lima aspek yaitu kompetensi pedagogik, kompetensi bidang studi keahlian, kompetensi manajerial, kompetensi kepribadian, dan kompetensi sosial.  Profil ideal guru SMK-KKTP termasuk dalam kategori sangat penting (88,27%). (2) Relevansi profil ideal guru SMK-KKTP dengan kurikulum Prodi PTM FT UNY mencapai 100%. Terdapat 59 kompetensi tambahan dalam kurikulum Prodi PTM FT UNY untuk menyiapkan lulusannya agar dapat bekerja di industri, menjadi instruktur, atau menjadi widyaiswara. (3) Pembelajaran di Prodi PTM FT UNY menurut persepsi dosen termasuk dalam kategori sangat memadai (84,26%) dan menurut persepsi mahasiswa termasuk dalam kategori memadai (77,89%). (4) Profil calon guru SMK-KKTP menurut persepsi guru pembimbing PPL termasuk dalam kategori baik (79,12%); menurut persepsi dosen termasuk dalam kategori baik (79,69%); dan menurut persepsi mahasiswa termasuk dalam kategori baik (80,21%).
THE PROVISION OF VERTICAL SOCIAL POCKETS FOR BETTER SOCIAL INTERACTION IN HIGH-RISE LIVING
Authors: Siew Bee Aw , Poh Im Lim
Published: September 2016

High-rise living makes it difficult for social communities to form despite the provision of several dedicated social spaces at ground, podium, mid- and roof-levels, partially due to the sheer number of residents per block. The pull of easily-accessed, solitary recreational activities such as surfing the Internet and watching television further exacerbates the problem. Social spaces need to be brought closer to residents to promote social interaction. This paper proposes to improve social interaction by supplementing currently stratified social spaces with vertically-connected social hubs using existing transitional spaces in high-rise living, such as the lift lobby, to create micro-communities comprising the residents of each respective floor in a cost-effective way. Previous research indicated that strong communities look after each other, indicating that the creation of microcommunities will create an effect not unlike the defensible space theory. Therefore, this paper analyses residential high-rise layouts based on chosen case studies in Malaysia, then suggests several possible design outcomes that turn the lift lobby into social spaces at every floor level.
LIVEABILITY PLANNING FOR CITIES: WITHIN THE ISLAMIC FRAMEWORK OF MAQASID AL-SHARI’AH
Authors: Md Dali Norimah , Abdullah Alias , Ahmad Sarkawi Azila
Published: September 2016

Liveability Planning is a new dimension of town planning practice. Town planning in Malaysia has been very physical and policy-biased. The soul component of liveability, quality of life and sustainability has been lacking. That is why environmental problems have now become the order of the day making urban living unhappy. Indeed liveability, quality of life and sustainability is one continuous process; a continuum. Conventional liveable indicators seem to concentrate more on economic and social wellbeing and lack religious elements. This gap is thought to be the missing link disabling human beings to live in harmony with nature. This research engages in the combined methodology which involves Focus Group Discussions, Interviews and Perception surveys in the formulation of the liveable city planning methodology based on Maqasid Al-Shari'ah (objectives of the Islamic Laws). Liveability planning practice that incorporate Maqasid into the conventional liveability indicators will render cities more liveable in the future.
SPATIOTEMPORAL LAND USE AND LAND COVER CHANGE IN MAJOR RIVER BASINS IN COMPREHENSIVE DEVELOPMENT AREA
Authors: Wan Ibrahim Wan Yusryzal , Muhamad Ludin Ahmad Nazri
Published: September 2016

Urbanization has significantly transformed spatial configuration of landscape structure which is triggered by population growth and government’s development policy. As a consequence, the changes disturbed the quality of natural environment and ecosystem. Historical experience and prediction of future land use and land cover change is important to understand the spatial characteristics and environmental consequences of development area. Evaluating the spatiotemporal in urban development is essential as an important component improving adaptive management in landscape planning. Thus, the objective of this paper is to discuss the spatiotemporal land use and land cover change in major river basins (Sungai Tebrau, Sungai Skudai, Sungai Pulai and Coastal Zone) in the rapid development region of Iskandar Malaysia. The past experience indicates rapid growth of population and substantial urban development changed the spatial structure of the region and there is tremendous transformation of land use and land cover in the present due to high demand for development. Analytical Hierarchical Process (AHP) and CA-markov chain model were used to analyze the relationship of variables and formulate the future spatial changes. Then landscape index is used to analyze the spatial characteristics of the changes. Remote sensing data and GIS were used to conduct the analysis for the study. Temporal satellite images between 2002 and 2013 were utilized as input data for the past changes and basis for future land use and land cover change projection (2020, 2025 and 2025). The result indicates different character of urban landscape changes in different periods and river basins. Past experience shows the significant change of agricultural and natural land converted into artificial land use especially in Skudai and Tebrau river basins. In addition, there was conversion of water body for development in the past especially along the river banks and coastal area in Johor Bahru city center. This trend will constantly restructure the existing landscape as projection shows the significant impact of future development. This situation could contribute to other possible issues such as microclimate change and increase run-off water, pollution and degradation of ecological values and services. This study provides a platform for decision-makers to interpret the situation of landscape structure change in relation with environmental consequence in the study area. Future development plan should thoroughly consider the character of future spatial development and anticipate the possible effect on the environment in the region.
RESEARCH FOR A COMPREHENSIVE AND ACTIVE PLANNING METHOD IN AN INDUSTRIAL-RESIDENTIAL MIXED AREAFOCUSED ON OTA CREATIVE TOWN VISION IN OTA WARD, TOKYO
Authors: Nohara Taku , Okamura Yu , Kawabara Susuma
Published: September 2016

Recently in Japan, the urban environment in industrial cities has been changing due to changes in the industrial, economical, and social structure. Ota Ward in Tokyo has small industrial districts, some of which are mixed-use areas. In the 1980’s there were 9,000 factories, but currently that number has been decreasing and although the factories still possess sophisticated skill-sets, their working environment is inadequate as it issurrounded by too many residential dwellings. In addition, it is too difficult to pass technical knowledge onto succeeding generations. In this research, we focus on a comprehensive and active planning method, specifically, on how to integrate manufacturing, community development, and city promotion so as to solve this kind of problem in mixed residential-industrial cities. Firstly, we investigated the local resources, which consisted of a small industrial network of a “mixed-used” status in Ota Ward that had access to an international airport. Secondly, we created a vision  encompassing these three points: (1) Stock (property) management, (2) Supporting Creative Industry, and (3) City Promotion via Industrial Tourism.Currently two projects are in progress: One is the industrial tourism event, “Ota Open Factory”, which is a one day program where many restricted access small factories are opened to the public in the mixed-used industrial area; and the other is “Creative Town Lab. Tamagawa”, which is an active community space (usable for education, workshops, meetings, exhibitions, events) that has been converted from a vacant factory.With these projects, we are trying to realize the area’s potential through activities, recreating a more creative and active city culture and identity.