bluuebunny/crossref_metadata_2025 huggingface dataset:
Narrativas de professores de uma escola democrática
Authors: Possato Beatris Cristina , Monção Maria Aparecida Guedes
Published: September 2022

Este relato de experiência apresenta parte de uma pesquisa de pós-doutorado realizada no Instituto Pandavas, escola comunitária de ensino fundamental que iniciou seu trabalho na década de 1970, baseada na antroposofia. Em 2013, passou a ser uma das escolas democráticas brasileiras, utilizando a pedagogia de projetos, na tentativa de diluir a separação dos alunos por séries/idades, bem como os horários fixos das aulas. Para isso, a escola delineou uma organização pedagógica em que os alunos definem os rumos de seu desenvolvimento, com base na autonomia, na emancipação de cada indivíduo e na gestão democrática. Para compreender esse contexto, realizou-se uma pesquisa narrativa com os professores e a coordenadora pedagógica dessa instituição. O objetivo deste relato é compreender as percepções de professores e coordenadora pedagógica sobre suas experiências na escola comunitária Pandavas. As narrativas mostraram que, por meio das assembleias, do diálogo, da “Educação para pensar, sentir e agir” e das práticas participativas, é possível aos alunos assumir seu papel de sujeitos sociais, coletivos, expandindo sua capacidade de ler o mundo, problematizando-o por meio de uma práxis transformadora. O relato dos professores foi possível permitiu observar que a educação para a humanização não é algo somente para os alunos, pois os professores igualmente são formados nessa perspectiva e podem se autorrealizar, expressando seus sentimentos, ao mesmo tempo em que consideram o lado emocional dos alunos no cotidiano escolar, em um processo dialógico que vislumbra uma educação para a transformação social.
Os sistemas tutores inteligentes e a adaptação do ensino aos perfis de aprendizagem do usuário
Authors: Lima Júnior Afonso Barbosa de , Silva Lebiam Tamar Gomes
Published: September 2022

No Século XXI, cresceu a demanda por ensino e aprendizagem mediados por tecnologia digital, especialmente ajustados aos perfis de aprendizagem de cada pessoa e às habilidades e às competências necessárias nas relações sociais contemporâneas. Assim, considerando que é necessário refletir sobre esse imperativo, este artigo tem o objetivo de descrever o processo de evolução e os requisitos básicos de funcionamento dos Sistemas Tutores Inteligentes (STI). Para alcançá-lo, empregou-se o método de pesquisa bibliográfica, tendo como principais bases de dados o Banco de Teses e Dissertações da Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) e as plataformas do Google Acadêmico e da Scientific Electronic Library Online (SCIELO). As fontes selecionadas para este estudo foram publicadas entre os anos de 1988 e 2017, nos idiomas português e espanhol, totalizando duas teses, dois capítulos de livros, três artigos, três dissertações e uma monografia. Como resultado, o texto apresenta um conjunto de informações explicitadoras sobre a evolução dos STI, com destaque para a arquitetura e o funcionamento básico desses sistemas informáticos. No final, apresenta-se o conceito de educação personalizada de Hoz (1988) e discute-se sobre seis princípios fundantes, que podem ampliar a capacidade de personalizar o ensino por sistemas tutores inteligentes.
Possíveis aproximações sobre o conceito de trabalho coletivo em Freinet e Freire
Authors: Varani Adriana , Costa Adriana Alves Fernandes
Published: September 2022

Os movimentos de revisita e análise dos/nos escritos de Freire, em “Pedagogia do Oprimido” e “Pedagogia da Esperança”, e de Freinet, em “Para uma Escola do Povo” e “Educação para o Trabalho”, sobre a existência do conceito de trabalho coletivo desvelam palavras que dialogam sobre os seus fundamentos e nos levam a compreender princípios fundantes de uma educação outra. Os textos, apesar de não mencionarem ipsis litteris tal expressão em sua forma composta, se revelam como leituras íntimas em relação ao tema. Freire discute os conceitos de solidariedade, dialogicidade/diálogo, reflexão, libertação, colaboração, comunhão e trabalho como ideias que corroboram outras leituras balizadoras do processo de compreensão sobre o trabalho coletivo. Freinet explora princípios que o cotejam por intermédio dos seguintes temas: educação pelo trabalho, cooperação, auto-organização. Ambos os teóricos remetem a leituras que lançam a concepção de trabalho coletivo em consonância com um projeto de educação que se faz para e com o povo. Enquanto Freire se detém aos processos de educação mais amplos e o coletivo se projeta no processo de humanização, Freinet trabalha com esses conceitos no campo da organização do trabalho escolar, nos levando a refletir e a estabelecer uma proposta concreta de trabalho cooperativo com estudantes e professores. São leituras que se constituem como dissonantes, uma vez que recuperam obras de autores e as aproximam de uma necessária educação para os excluídos, para e com as vozes dissonantes da sociedade, as quais, ao mesmo tempo, fazem parte da composição social.
Os planos nacionais de educação (2001-2010 e 2014-2024) no campo da educação
Authors: Canan Silvia Regina , Cristo Fernando de
Published: September 2022

Trata-se de uma resenha crítica do livro “Os Planos Nacionais de Educação (2001-2010 e 2014-2024) no Campo da Educação Superior”, de autoria de Talita Zanferari e Maria de Lourdes Pinto de Almeida.
Educação do campo
Authors: Moreto Charles , Gerke Ana Carla Loss Furlan
Published: September 2022

Trata-se de resenha elaborada a partir do livro de Mônica Nickel, sob o título "Educação do Campo: formação continuada de professores na prática". A obra discute o processo de formação continuada de professores do campo no município de Domingos Martins e sua contribuição na práxis docente. Destaca a importância de se estabelecer parcerias entre a Secretaria de Educação e a Universidade, com vistas ao fortalecimento da formação continuada no município. A formação continuada de professores do campo constituiu-se processual e historicamente, contribuindo para o fortalecimento da identidade étnica e cultural dos povos do território, para a mudança da prática pedagógica, configurando-se como política pública no município.
A Escada Ponteana e o Estatuto da Pessoa com Deficiência
Authors: Rebouças Glauber Dantas
Published: September 2022

O artigo tem por finalidade analisar a revolução promovida pelo Estatuto da Pessoa com Deficiência (Lei nº 13.146, de 2015 – EPD) na teoria das incapacidades, considerando as pessoas com deficiência intelectual ou mental plenamente capazes. Também é objetivo do trabalho apresentar o panorama doutrinário sobre as alterações, ressaltando as críticas que foram lançadas ao Estatuto. Partindo-se da premissa de que tanto a teoria das incapacidades como a Convenção Internacional sobre os Direitos das Pessoas com Deficiência possuem a finalidade de proteção daqueles que, por suas limitações, mostram-se, nas relações sociais, vulneráveis frente às demais, questiona-se até que ponto a presunção legal de capacidade fática das pessoas com deficiência mental ou intelectual mostra-se adequada à própria razão de ser do Estatuto. Buscar-se-á, à luz da Escada Ponteana, soluções para a celeuma, apresentando-se sugestões, de lege lata e de lege ferenda.
Does Cannabidiol (CBD) in Food Supplements Pose a Serious Health Risk? Consequences of the EFSA Clock Stop Regarding Novel Food Authorisation
Authors: Lachenmeier Dirk W. , Sproll Constanze , Golombek Patricia , Walch Stephan G.
Published: September 2022

At present, foods containing cannabidiol (CBD) and other cannabinoids are internationally being widely advertised and sold in increasing quantities. In the European Union (EU), these products require pre-marketing authorisation under the novel food regulation, so that all available CBD oils and CBD-containing food supplements in the EU are currently placed on the market with an infringement of the food laws. Currently, 19 CBD applications are under assessment at the European Food Safety Authority (EFSA). During the initial assessment of the application files, EFSA located several knowledge gaps that need to be addressed before the safety evaluation of CBD can be concluded. Namely, the effect of CBD on the liver, gastrointestinal tract, endocrine system, nervous system, psychological function, and reproductive system needs to be clarified. Nevertheless, the available literature allows a benchmark dose (BMD)-response modelling of several bioassays, resulting in a BMD lower confidence limit (BMDL) of 20 mg/kg bw/day for liver toxicity in rats. Human data in healthy volunteers found increases in the liver enzymes alanine aminotransferase (ALT) and aspartate aminotransferase (AST) in a study at 4.3 mg/kg bw/day, which was defined by EFSA as a lowest observed adverse effect level (LOAEL). The EFSA panel currently concluded that the safety of CBD as a novel food cannot be evaluated, leading to a so-called clock stop of the applications until the applicants provide the required data. Meanwhile, the authors suggest that CBD products still available on the EU market despite the lack of authorisation must be considered as “unsafe”. Products exceeding a reference dose of 10 mg/day must be considered as being “unfit for consumption” (Article 14(1) and (2) (b) of Regulation No 178/2002), while the ones in exceedance of the human LOAEL must be considered “injurious to health” (Article 14(1) and (2) (a) of Regulation No 178/2002).
Macroscopic and Histological Descriptive Gonadal Study in Different Stages of Sexual Maturity of the Burmeister’s Porpoise Phocoena spinipinnis from Peru
Authors: Vega Diana , Van Waerebeek Koen , Alfaro-Shigueto Joanna , Reyes Julio C. , Van Bressem Marie-Francoise
Published: September 2022

The morphology and maturation process of gonads of 70 Burmeister´s porpoises, with body lengths ranging 135–183 cm (n= 34 females) and 64.5-182 cm (n= 36 males) were described. Samples were collected in six ports of central and northern Peru in 1987-1999. In the field, females were classified as immature, mature (resting, lactating, pregnant) and males as immature, pubescent and mature based on, respectively, the presence of ovarian corpora and the relative quantity of semen in cut epididymides. The ovaries of P. spinipinnis are ovoid or bean-shaped and flattened, with corpora modifying surface appearance. In the laboratory, ovaries were examined macro- and microscopically, measured, weighed and sliced in 1-3 mm sections. The number of corpora ovarica (lutea, albicantia, atretica) found in each ovary as well as their macroscopic and microscopic characteristics were documented in some detail. The follicles, their oocytes and nucleus were measured. Follicular development in P. spinipinnis is predominantly left-sided, but occurs in both ovaries in 16.3% of females, mainly in those with numerous corpora. Macroscopically, several corpora atretica with luteinization had characteristics similar to those of corpora albicantia, making microscopic determination essential. Inconclusive evidence of recent ovulation was found in January. Two of three immature females showed good follicular development in March and April. The body length at 50% sexual maturity in females was estimated at 152.7 cm. There was no evidence of reproductive senescence. The testes of P. spinipinnis are elongated and cylindrical. Of the 36 males examined macroscopically, 7 were immature, 5 pubescent and 24 mature. The histological analysis determining the presence and abundance of Sertoli cells, spermatogonia, spermatocytes, spermatids and spermatozoa, the relative amount of interstitial tissue, the elongation and mean diameter of the seminiferous tubules and the relative size of the lumen allowed to confidently determine sexual maturity status. The field evaluation of maturity based on the presence of sperm in the epididymides is a useful but, in 8.3% of cases, not exact method. For males the body length at 50% sexual maturity was estimated at 157 cm. No histological evidence of male reproductive seasonality was found. Spermatogenesis was perceptible year-round and tubule diameters had non-specific variations for each month.
Contribution of Symptomatic, Herbal Treatment Options to Antibiotic Stewardship and Microbiotic Health
Authors: Nausch Bernhard , Bittner Claudia B. , Höller Martina , Abramov-Sommariva Dimitri , Hiergeist Andreas , Gessner André
Published: September 2022

Epithelial surfaces in humans are home to symbiotic microbes (i.e., microbiota) that influence the defensive function against pathogens depending on the health of the microbiota. Healthy microbiota contribute to the well-being of their host in general (e.g., via the gut-brain-axis), and their respective anatomical site in particular (e.g., oral, urogenital, skin or respiratory microbiota). Despite efforts towards a more responsible use of antibiotics, they are often prescribed for uncomplicated, self-limiting infections and can have a substantial negative impact on the gut microbiota. Treatment alternatives such as non-steroidal anti-inflammatory drugs may also influence the microbiota and thus can have lasting adverse effects. Herbal drugs offer a generally safe treatment option for uncomplicated infections of the urinary or respiratory tract. Additionally, their microbiota preserving properties allow for a more appropriate therapy of uncomplicated infections without contributing to an increase in antibiotic resistance or disturbing the gut microbiota. Here, herbal treatments may be a more appropriate therapy with a generally favorable safety profile.
Vaccine Side Effects Following COVID-19 Vaccination with Inactivated Vaccines in Zimbabwe
Authors: Makadzange Azure Tariro , Gundidza Patricia , Lau Charles , Dietrich Janan , Beta Norest , Myburgh Nellie , Elose Nyasha , James Wilmot , Stanberry Lawrence , Ndhlovu Chiratidzo
Published: September 2022

Vaccination is one of the most effective methods for preventing morbidity and mortality from COVID-19. Vaccine hesitancy has led to a decrease in vaccine uptake; driven by misinformation, fear, and perceptions of vaccine safety. Whole inactivated vaccines have been used in one-fifth of the vaccine recipients in Africa, however there is limited real-world data on their safety. We evaluated the reported side effects and factors associated with reported side effects following vaccination with whole inactivated COVID-19 vaccines - BBiBP-CorV (Sinopharm) and CoronaVac (Sinovac). A quantitative survey evaluating attitudes and side effects from vaccination was administered to 1016 adults presenting at vaccination centers. Two follow-up telephone interviews were conducted to determine side effects after the first and second vaccination dose. Overall, the vaccine was well tolerated; 26.0% and 14.4% reported side effects after the first and second dose respectively. The most frequent local and systemic side effects were pain at the injection site and headaches respectively. Most symptoms were mild, and no participants re-quired hospitalization. Participants who perceived COVID-19 vaccines as safe or had a personal COVID-19 experience were significantly less likely to report side effects. Our findings provide data on the safety and tolerability of whole inactivated COVID-19 vaccines in an African population, providing the necessary data to create effective strategies to increase vaccination and support vaccination campaigns.
Z2-$\gamma$: an Application of Zienkiewicz-Zhu Error Estimator to Brain Tumor Detection in MR Images
Authors: Falini Antonella
Published: September 2022

Brain tumors are abnormal cells growth in the brain tissues that can be cancerous, or not. In any case, they could be a very aggressive disease that should be detected as early as possible. Usually, magnetic resonance imaging (MRI) is the main tool commonly adopted by neurologists and radiologists to identify and classify any possible anomalies present in the brain anatomy. In the present work, an automatic unsupervised method called Z2-$\gamma$, based on the use of adaptive finite-elements and suitable pre-processing and post-processing techniques, is introduced. In particular, the proposed methodology is able to automatically classify whether a given MR image represents a healthy or a diseased brain and in this latter case, is able to locate the tumor area.
G-Net Light: A Lightweight Modified Google Net for Retinal Vessel Segmentation
Authors: Iqbal Shahzaib , Naqvi Saud , Ahmed Haroon , Saadat Ahsan , Khan Tariq M.
Published: September 2022

Convolutional neural network architectures have become increasingly complex, which has improved the performance slowly on well-known benchmark datasets in the recent years. In this research, we have analyzed the true need for such complexity. We have introduced G-Net light, a lightweight modified GoogleNet with improved filter count per layer to reduce feature overlaps and complexity. Additionally, by limiting the amount of pooling layers in the proposed architecture, we have exploited the skip connections to minimize the spatial information loss. The investigations on the proposed architecture are evaluated on three retinal vessel segmentation publicly available datasets. The proposed G-Net light outperforms other vessel segmentation architectures by reducing the number of trainable parameters..
Massively parallel multi-target CRISPR system interrogates Cas9-based target recognition, DNA cleavage, and DNA repair
Authors: Zou Roger S. , Marin-Gonzalez Alberto , Liu Yang , Liu Hans B. , Shen Leo , Dveirin Rachel K. , Luo Jay X. J. , Kalhor Reza , Ha Taekjip
Published: September 2022

CRISPR-Cas9 nucleases, and particularly Streptococcus pyogenes Cas9, are widespread tools for genome editing. However, many aspects of intracellular Cas9 activity and the ensuing DNA damage response remain incompletely characterized. In order to address these issues, we developed a multiplexed CRISPR approach, where a single, degenerate multi-target gRNA (mgRNA) directs the Cas9 enzyme to target hundred endogenous sites at once. When combined with next-generation sequencing readouts, this system enables interrogation of Cas9 activity and DNA double-strand break (DSB) repair response in high-throughput. Here, we present a step-by-step protocol to deliver a Cas9:mgRNA ribonucleoprotein complex into cultured cells and measure key processes related to Cas9 activity and DSB repair.
ASSESSMENT OF DOSE CALIBRATOR PERFORMANCE FOR ACCURATE PATIENT DOSE ADMINISTRATION AND BETTER STAFF PROTECTION IN A BUSY NUCLEAR MEDICINE DEPARTMENT QUALITY MATTERS
Authors:   Department of Radiology, Lady Reading Hospital-MTI, Peshawar, Pakistan., Yaseen Muhammad , Ali Amir ,   Department of Radiology, Lady Reading Hospital-MTI, Peshawar, Pakistan., Hassan Kharita Mohammad ,   Department of Occupational & Health Safety- Medical Physics Section, Hamad Medical Corporation, Doha, Qatar., Burki Shamsullah ,   Department of Radiology, Lady Reading Hospital-MTI, Peshawar, Pakistan., Khan Banaras ,   Department of Physics, Qurtuba University of Science & IT, Peshawar, Pakistan., Iqbal Javaid ,   Department of Nuclear Medicine, Liaquat National Hospital, Karachi., Kamal Eslam ,   Department of Medical Physics, Burjeel Medical city, Abu Dhabi - United Arab Emirates.
Published: September 2022

Background: To assess the performance of the Capintec- CRC-15R dose calibrator which is in use atLiaquat National Hospital (LNH) Karachi, Pakistan for patient dose administration. Method: This quantitative study was conducted at Nuclear Medicine department, Liaquat National Hospital,Karachi during the period from July-December 2015. The quality control tests of calibrator were performed using standard sources i.e. Co-57, Ba-133 & CS-137 and data was analyzed for performance assessment of calibrator. Results: Capintec CRC-15R calibrator was found in perfect working condition during daily physical inspections having consistent stable values with normal background readings. The precision test results were within the tolerance limits of Â± 5% and accuracy of Co-57, Ba-133 & CS-137 were (-0.36%, -0.36% & -0.43%) respectively. The constancy tests for all the three (03) standard sources were within the specified limits of Â± 10% and the activity-time graph was linear. The geometry test results were consistent upto 12 cm height (1.8%) and a sharp decrease of 11% was observed in activity at 20 cm height resulting in less activity measurements. The volume dependency results were consistent up to 3ml volume while a substantial deviation of 2.8 % was observed at 5ml which was within the tolerance limit of Â±10%. Conclusion:The results of the quality control tests in our study for the dose calibrator- Capintec CRC-15R showed that the readings were within the specified limits and the calibrator was in good working condition which not only ensure right patient dose administration but also better staff protection.
PRESENTATION ATYPIQUE DE LA MALADIE DERDHEIM-CHESTER :ATTEINTE PULMONAIRE PSEUDO-TUMORALE SANS ATTEINTE OSSEUSE ET REVUE DE LITTERATURE
Authors:   Departement de Pneumologie, Hopital Ibn Sina, CHU, Universite MohamedV, Rabat, Maroc., A. Anissa-Sahan Abdoulkader , Leila Herrak ,   Departement de Pneumologie, Hopital Ibn Sina, CHU, Universite MohamedV, Rabat, Maroc., Mouhoubo Ibrahim ,   Laboratoire Danatomopathologie, Hopital Ibn Sina, CHU, Universite Mohamed V, Rabat, Maroc., Aziza Rhanim ,   Departement de Pneumologie, Hopital Ibn Sina, CHU, Universite MohamedV, Rabat, Maroc., Asma Jniene ,   Departement de Pneumologie, Hopital Ibn Sina, CHU, Universite MohamedV, Rabat, Maroc., Ftouh Mustapha El. ,   Departement de Pneumologie, Hopital Ibn Sina, CHU, Universite MohamedV, Rabat, Maroc., Leila Achachi ,   Departement de Pneumologie, Hopital Ibn Sina, CHU, Universite MohamedV, Rabat, Maroc.
Published: September 2022

Erdheim-Chester disease (ECD) is a rare form of non-Langerhansian histiocytosis classified by WHO since 2016 as a group L hematological neoplasia. Its pathophysiology is very complex and its multi-systemic character explains the plurality of clinical-radiological presentations. Bone involvement is almost constant while associated lung involvement is found in 50% of cases with non-specific clinical signs such as dyspnea and cough. Imaging provides an undeniable diagnostic contribution but confirmation of ECD is based on histopathology with immunohistochemical study. The search for the BRAF mutation by molecular biology has innovated the therapeutic management.The aim of our report is to relate a rare case of Erdheim-Chester disease in a 40-year-old man with an atypical pulmonary pseudotumor presentation without bone involvement and the diagnosis difficulty faced. Reporting of this type of aggressive disease should have an impact on early diagnosis and better prognosis.
A COMPARATIVE CLINICAL STUDY ON THE EFFECT OF MRITTIKA LEPA AND LODHRADI LEPA IN YUVANAPIDIKA W.S.R TO ACNE VULGARIS
Authors:   Professor, Postgraduate Department of Swasthavritta, S.J.G. Ayurvedic Medical College, Koppal, Karnataka., C. Nagalapur Prabhu , Kanaj Budesh ,   Professor, Department of Swasthavritta, D.G.M. Ayurvedic Medical College, Gadag, Karnataka.
Published: September 2022

Acne vulgaris is a condition where it is characterized by Microcomedones, the earliest lesions of acne, appear at adrenarche, when androgens of adrenal origin begin to stimulate follicular hyperkeratosis and sebaceous hyperplasia in pilosebaceous units on the face.1Mud is one of the rarely used natural modes of treatment in any of the cases. But Black Mud is very useful in conditions of skin ailments.Lodhradilepa has anti-inflammatory action.Therefore, the study was planned to observe the comparative effect of mrittikalepa and lodhradilepa in the management of Acne vulgaris. In the study 30 patients were selected according the classical signs and symptoms of Yuvanapidika& divided into two equal groups comprising of 15 patients in each group. In Group A, 4 patients (26.67%) got mild relief, 3 patients (20%) got moderate relief and 8 patients (53.33%) got marked relief. In Group B, 4 patients (26.67%) got mild relief, 6 patients (40%) got moderate relief and 5 patients (33.33%) got marked relief.Black Mud easily combines with water, absorbs all the seven colours of skin and does not have any adverse effects. It gives cooling effect to the body, because of its moisture retention capacity and it increases the blood circulation and energizes the various skin tissues.2The drug Lodhra, Vachaand Dhanyakaare Kushtagna, Vranaropaka,Vedanasthapaka,Shotahara3might have resulted in good relief.
OCULAR PATHOLOGY OF HYPEROPIC PATIENTS PRESENTING TO THE TERTIARY HEALTH CARE CENTRE
Authors:   Professor & Head, Dept. of Ophthalmology, MLB Medical College Jhansi, India., Kumar Jitendra , Jain Apurva ,   Junior Resident, Dept. of Ophthalmology, MLB Medical College Jhansi, India., Gupta Archie ,   Junior Resident, Dept. of Ophthalmology, MLB Medical College Jhansi, India.
Published: September 2022

Purpose:To study the ocular pathology of hyperopic patients presenting to the tertiary health care centre. Methods: This was a retrospective observational study that involved 60 eyes of 30 patients with hypermetropia complaining of diminution of vision with asthenopic symptoms like tiredness of eyes, frontal or frontotemporal headache, watering and mild photophobia. There were three groups based on the criteria of age, i.e, <20 years, 20-40 years, 40-60 years with each group comprising of 10 patients. Complete ophthalmic examination was done in diffuse light followed by direct and indirect opthalmoscopic examination. Results:There were 15 males and 15 females. The common hypermetropiarelated findings in patients varying between age of 0-20 years was strabismus and amblyopia. Recurrent styes, recurrent blepharitis infection, recurrent chalazion were seen in equal proportions in all age groups. Primary open angle glaucoma and angle closure glaucoma were reported more in adults ranging between 20-40 years and 40-60 years.Fundus examination in high hypermetropic patients revealed a small optic disc with ill defined margins simulating papillitis which is pseudopapillitis because there is no swelling of the disc and the retina shines due to greater brilliance of light reflections giving shot silk appearance of retina. Conclusion:Hyperopia also termed hypermetropia or farsightedness, is a common refractive error in children and adults. Its effect on an individual and the symptoms produced varies greatly, depending on the magnitude of hyperopia, the age of the individual, the status of the accommodative and convergence system, and the demands placed on the visual system. Individuals with uncorrected hyperopia may experience symptoms such as blurred vision, asthenopia (e.g., headaches and eyestrain) while reading, accommodative/binocular dysfunction, amblyopia, and/or strabismus. Furthermore, uncorrected amblyopia in case of adults can lead to various complications like open angle or angle closure glaucoma, uveal effusion syndrome, non arteritic anterior ischemic optic neuropathy, central serous chorioretinopathy, age related macular degeneration, etc.
PROBIOTIC AND FUNCTIONAL ATTRIBUTES OF PROBIOTIC LEUCONOSTOCCITREUM STRAIN MRKAK2
Authors:   Molecular Biology and Microbial Biotechnology Laboratory, Division of Life Sciences, Institute of Advanced Study in Science and Technology (IASST), Guwahati-781035, Assam, India., Kumar Arun ,   Department of Biotechnology, Gauhati University, Guwahati-781014, Assam, India., C. Kalita Mohan ,   Department of Biotechnology, Gauhati University, Guwahati-781014, Assam, India., R. Khan Mojibur ,   Molecular Biology and Microbial Biotechnology Laboratory, Division of Life Sciences, Institute of Advanced Study in Science and Technology (IASST), Guwahati-781035, Assam, India.
Published: September 2022

The development of functional foods and their safety assessment is required for well-being of the human health. In the present study, we have isolated and identified a potential probiotic bacterium from the fermented garlic pickle that exhibits an improvement in health status upon consumption. In order to assess the probiotic potential of isolated bacterium, in vitro probiotic tests were performed, including tolerance to acid, pancreatin,bile, and adhesion ability to gastrointestinal cell lines. The safety assessment of probiotic strain was evaluated using an antibiotic susceptibility test. The obtained results showed that the isolated strain was identified as Leuconostoccitreum strainMRKAK2 based on 16S rRNA sequencing. The isolate demonstrated tolerance to acidic pH (pH 1.0 and pH 3.0), 0.3% pepsin (pH 2.0), 0.1% pancreatin (pH 8.0), bile (0.3% and 1%) and efficient adhesion to gastrointestinal cell line HT-29.The strain also exhibited susceptibility towards antibiotic ampicillin, tetracycline, streptomycin, and sulphatriad, whereas it showed resistance against chloramphenicol and penicillin-G.The antibiotic sensitivity pattern of the strain was similar to other Lactobacillus strains.Thus, our results exhibitedthat L.citreum strain MRKAK2 is a potential probiotic strain for developingfermented functional foods.
UTILIZACION DE UNA PRACTICA INFORMATIZADA PARA LA ENSENANZA DE UN EXPERIMENTO DE GRAVIMETRIA
Authors:   Universidad Autonoma De CampecheAv. Agustin Melgar s/n, Col. Buenavista, Campeche, Mexico., Manuel De Jesus Mex-Alvarez Rafael , Guillermo-Chuc Giselle ,   Universidad Autonoma De CampecheAv. Agustin Melgar s/n, Col. Buenavista, Campeche, Mexico., Yanez-Nava David ,   Universidad Autonoma De CampecheAv. Agustin Melgar s/n, Col. Buenavista, Campeche, Mexico., Magali Guillen-Morales Maria ,   Universidad Autonoma De CampecheAv. Agustin Melgar s/n, Col. Buenavista, Campeche, Mexico., Alberto Quijano Garcia Roman ,   Universidad Autonoma De CampecheAv. Agustin Melgar s/n, Col. Buenavista, Campeche, Mexico., Isabel Novelo-Perez Maria ,   Universidad Autonoma De CampecheAv. Agustin Melgar s/n, Col. Buenavista, Campeche, Mexico.
Published: September 2022

The covid-19 pandemic forced education to seek new ways of teaching and learning In particular, due to the fact that experimental sciences such as chemistry require training in the laboratory and that attendance at these training spaces was interrupted by social isolation, the need arose to investigate new ways of acquiring procedural skills. The objective of this work was to estimate the usefulness of a didactic material, a computerized practice, in the academic achievement of students through the analysis of the experimental performance obtained before and during the use of the computerized practice. It was observed that the students who had the didactic material at their disposal improved their performance, measured by the Hake index. For this reason, it is estimated that computerized practice is useful to improve academic performance in the practice laboratory.
EVALUATION DE LA TOXICITE SUBAIGUE DES ECORCES DE RACINE DE CASSIA SIEBERIANA
Authors: Ndouffou Celestin Ehoussou , Tianga Yaya Soro , Sirabana Coulibaly , Georges Abizi
Published: September 2022

Cassia sieberiana est un arbre de 8 a 10 metres de hauteur, utilise pour traiter diverses maladies notamment le paludisme, la dysmenorrhee et biens dautres pathologies. Notre objectif est de contribuer a la valorisation des plantes de la pharmacopee africaine, par levaluation de la toxicite subaigue de lecorce de racine de Cassia sieberiana, plante utilisee dans la therapie en Cote dIvoire. La toxicite subaigue fournit des informations sur les risques pour la sante que peut entraÃƒÂ®ner une exposition repetee pendant une periode de temps relativement limitee. Ladministration quotidienne sur 28 jours par voie orale des doses de 100 150 et 200 mg/kg de poids corporel (PC) dextrait aqueux decorce de racine de Cassia sieberiana (EACS), na eu aucun effet significatif sur la croissance des rats, ni sur le poids relatif du cÃ…Â“ur, du foie, de la rate, des reins des rats traites comparativement aux temoins. Aux mÃƒÂªmes doses, EACS na aucune influence sur les parametres biochimiques que sont les transaminases, la bilirubine, la creatinine et luree, ni sur les parametres hematologiques en comparaison aux temoins. Lobservation des coupes histologiques du cÃ…Â“ur, du foie et des reins na revele aucune lesion au niveau de ces organes. Les resultats obtenus au cours de cette etude montrent que Cassia sieberiananest pas toxique aux doses etudies et par cette voie dadministration.
ONLINE LEARNING DURING COVID 19 PANDEMIC: PERSPECTIVE OF NURSING FACULTY
Authors: Keith M. Espina , MAN , RN Sedfrey
Published: September 2022

This research determined the perception of nursing faculty toward online learning in a College of Northern Mindanao in the Philippines. This study used a descriptive online survey involving a sample of 21 faculty members. Statistical tools employed were descriptive statistics, Mann-Whitney U test, and Kruskal-Wallis test. Research findings indicated that the majority of faculty had intermediate computer competency and had no training in online teaching, with only a few having a very stable internet connection. Faculty considered online education to result in more academic dishonesty, impersonal and lack feeling compared to face-to-face classes, and difficult to manage in terms of technology. Additionally, faculty were undecided if they are in favor of online education. The faculty significantly differed whether they are in favor of online education based on age, sex, college, educational attainment, years in teaching, academic rank, level taught, and employment status. Faculty of Higher Education Institutions must be provided with continued support and training as they adapt to the new normal in the higher education landscape and as they embrace the instructional challenges brought by the Coronavirus disease 19 pandemic.
Role of financial sector development in foreign direct investment inflows in BRICS
Authors: Tsaurai Kunofiwa
Published: September 2022

This study examined the influence of financial sector development on FDI inflows in BRICS using panel data (1991–2020) analysis methods. The influence of the complementarity between the financial sector and human capital development on FDI inflows was also examined in the context of BRICS using the same data set and econometric methodologies. The advantage of this study is that the results are used as a basis by BRICS countries to develop financial sector development policies that attract significant FDI inflows. Financial sector development (model 2 and 3 of the pooled ordinary least squares approach) significantly enhanced FDI inflows. Human capital development (model 3 of the fully modified ordinary least squares) was found to have had a significant positive effect on FDI inflows in BRICS group of countries. The combination between financial and human capital development under (1) model 1 of the fully modified ordinary least squares and (2) models 2 and 3 of the pooled ordinary least squares (POLS) was observed to have significantly enhanced FDI inflows in BRICS. The study outlines the financial and human capital development recommendations that need to be implemented to facilitate more FDI inflows.
Acknowledgment Kunofiwa Tsaurai is grateful for the moral support from his employer, University of South Africa.
The Ratification of Omnibus Law: A Sign of Democratic Deconsolidation in Indonesia
Authors: Arifin Muchamad Zaenal , Nugroho Wahyu Budi , Cortés Ana María Naranjo , Purnama Pricilia
Published: September 2022

Indonesia as a post-authoritarian democratic country has made impressive progress in its democratic transition. However, there is a significant contradiction in the democratic process, particularly in policy and law-making. This article queries to what extent democratic deconsolidation contributes to the ratification of the Omnibus Law on Job Creation in Indonesia. This research uses a qualitative method by using academic literature, news analysis, and official government documents. The study employs various theoretical approaches, including horizontal accountability by Wolfgang Merkel, discursive participation by Jürgen Habermas, and democratic civil-military relations by Samuel Huntington. The first finding shows that the accumulation of Joko Widodo's political power has affected the quality of debate and the agreement during the deliberation of the Omnibus Law in the parliament. Second, the opaque process by limiting public participation has narrowed the space for the democratic mobilization of the citizens. Third, the increasing number of retired armed forces in domestic affairs has resulted in the dual function of military power in securing the country and the economic development agenda. The study shows that the deconsolidation of democracy has contributed to the ratification of the Omnibus Law on Job Creation which was deliberated through a non-transparent mechanism.
About the pathologist-morphometrist Georgy Gerasimovich Avtandilov
Authors: Zubritsky Alexander
Published: September 2022

The article shows the life and creative path of Georgy Gerasimovich Avtandilov, the outstanding domestic pathologist-morphometrist, who for the first time created the Soviet school of quantitative pathological anatomy. A Doctor of Medical Sciences, Professor, Academician of the Russian Academy of Natural Sciences, Honored Doctor of Kabardino-Balkaria, Honored Scientist of the RSFSR and the Republic of North Ossetia-Alania, Avtandilov was born in the town of Kizlyar. After graduating from high school, he entered the Novocherkassk Industrial Institute, but in his second year of studies he was called up to serve in the Workers-Peasant Red Army in the town on the Bialystok ledge of the border, where in 1941 he was captured and held in the Lamsdorf concentration camp almost until the end of the war, having gone through a living hell. After the end of the war and the end of the North Ossetian Medical Institute, the fate of G. G. Avtandilov developed in such a way that the choice was made for life in favor of pathological anatomy.
Dissolved oxygen control strategies for water treatment: a review
Authors: Li Daoliang , Zou Mi , Jiang Lingwei
Published: September 2022

Dissolved oxygen (DO) is one of the most important water quality factors. Maintaining the DO concentration at a desired level is of great value to both wastewater treatment plants (WWTPs) and aquaculture. This review covers various DO control strategies proposed by researchers around the world in the past 20 years. The review focuses on published research related to determination and control of DO concentrations in WWTPs in order to improve control accuracy, save aeration energy, improve effluent quality, and achieve nitrogen removal. The strategies used for DO control are categorized and discussed through the following classification: classical control such as proportional-integral-derivative (PID) control, advanced control such as model-based predictive control, intelligent control such as fuzzy and neural networks, and hybrid control. The review also includes the prediction and control strategies of DO concentration in aquaculture. Finally, a critical discussion on DO control is provided. Only a few advanced DO control strategies have achieved successful implementation, while PID controllers are still the most widely used and effective controllers in engineering practice. The challenges and limitations for a broader implementation of the advanced control strategies are analyzed and discussed.
Experimental investigations of open-channel flow and velocity to develop a predictive tool from a laboratory small scale to real-world large scale
Authors: Abushandi Eyad
Published: September 2022

Open channel flow and velocity behaviour presents a dilemma for drainage systems designers where hydrologic parameters are fluctuating in space and time. The experience of having extreme flash floods almost every year is flustering the need for understanding the flow behaviour at different altitudes. In this study, open channel experimental efforts were made to model flow and velocity profiles. The three-dimensional (3D) open channel flow and velocity profiles are generated at two types of roughness namely steel (smooth) and concrete (rough beds). The experiments included different slope gradients and flow measurements at different distances. The channels slope ranges between 0 and 4.7% with an interval of 0.2%. Multiple linear regression (MLR) was applied to quantify the flow for longer distance while Kriging extrapolation proxy was used to generate 3D surfaces of flow and velocity. The results showed that the flow in concrete channel is decreasing by moving to the end of channel due to higher frictional resistance while it is rising up for the steel channel. In average, the velocity has been increased by 7.4% for steel and 6.1% for concrete channels at a changing slope.
Depression among Older Adults in Indonesia: Prevalence, Role of Chronic Conditions and Other Associated Factors
Authors: Handajani Yvonne Suzy , Schröder-Butterfill Elisabeth , Hogervorst Eef , Turana Yuda , Hengky Antoninus
Published: September 2022

Background:

Depression is one of the most common illnesses worldwide, with a prevalence of 5.7% among older adults aged over 60. Depression is a severe health condition that can significantly affect the quality of life.

Objective:

The objective of this study is to investigate the determinant factors of depression among older adults in Indonesia.

Methods:

Data of 4236 adults of 60 years old and over were taken from the fifth wave of the Indonesian Family Life Survey (IFLS-5). Sociodemographic and multiple health-related variables collected through interviews and measurements were analyzed. Multivariate logistic regression was used to evaluate depression and its associated factors.

Results:

The prevalence of depression assessed using ten questions from the Center for Epidemiologic Studies Depression Scale (CES-D 10) was 16.3%. Significant associated factors for depression were moderate and low subjective economic status, living in Java or other regions outside Sumatra and Java, no life satisfaction, self-perceived as having poor health, having dependency (IADL scores), and experienced falls and insomnia. Among chronic conditions, stroke, arthritis, and hearing impairment were also more common in depressed older adults.

Conclusion:

Predictors of depression identified in this study may be used to help prevent and improve depression in Indonesian older adults, especially those who live on Java. Improvement in healthcare, especially in the prevention and rehabilitation of stroke, arthritis, possible frailty (falls and dependency), hearing impairment, and insomnia, concurrent with early detection of depression in these chronic conditions, may help create a better quality of life among Indonesian older adults.
The Experiences of Parents of Youth Abusing Substances in the Selected Hospitals in Limpopo Province, South Africa
Authors: Hlahla Lina S. , Mothiba Tebogo M.
Published: September 2022

Background:

It is in the parents’ interest to protect their youth and keep them away from substance abuse. It can be particularly disturbing for them to learn that their youth child abuses substances. When a youth abuses the substance, it is normal for parents to experience feelings of guilt and sadness. Stress levels can increase when caring for a youth abusing substances.

Methods:

A qualitative approach was used in the study. The explorative, descriptive, and contextual design was adopted to explore the experiences of parents of youth abusing substances. Purposive sampling was used to identify the participants for the study. Data was collected through Semi-structured interviews. Data were analyzed using Tesch’s steps for qualitative data analysis.

Results:

Results indicated that the parents go through various experiences, including poor physical health, poor emotional health, lack of knowledge related to substance abuse, lack of knowledge on where to get help, and inability to assist their youth out of substances. They also lack knowledge of substances abuse.

Conclusion:

The study findings indicated that the parents of youth abusing substances have diverse experiences when dealing with their youth abusing substances. Parents should be equipped with knowledge and skills to manage different situations as they arise. This can be achieved through substance abuse awareness campaigns for the parents.
Retrospective Evaluation of Acute Scrotum in Children: Eleven Years Experience of a Single Centre
Authors: Uysal Mehmet , Işık Bülent
Published: September 2022

Objective
Incidence of underlying causes and outcomes in patients followed up and treated in the last 11 years by the Pediatric Surgery Clinic of our hospital with the diagnosis of acute scrotum in childhood were analyzed retrospectively.

Materials and Methods
A total of 216 patients diagnosed with acute scrotum by the Pediatric Surgery Clinic between November 2010 and October 2021 were included in this study. The age, presentation complaints, physical examination, laboratory and radiological results, additional anomalies, medical and surgical treatment results of the patients were analyzed.
Results
The patients were aged between 3 weeks to 17 years, with a mean age of 9.9 ± 4.4 years. Pain and swelling are most common in acute scrotum present on the right side in 119 patients (55.1%) and on the left side in 97 patients (44.9%). Causes of acute scrotum were orchitis /epididymoorchitis (O/EO) in 98 (45.4%), strangulated inguinal hernia (SIH) in 52 (24.1%), testicular torsion (TT) in 38 (17.6%), and torsion of testicular appendage (TTA) in 11 (5.1%), testicular rupture in 5 (2.3%), idiopathic scrotal edema 5 (2.3%), intravaginal abscess 3 (1.4%), testicular cancer 2 (0.9%), hydrocele 2 (0.9%). Vesicoureteral reflux was detected in 7 (7.1%) of the patients with O/EO.
Conclusion
In this series, O/EO was found to be the most common cause of acute scrotal pain. The acute scrotum should be approached like the acute abdomen because only lower quadrant abdominal pain may be the cause of testicular torsion.
'Hoe zal een toekomstige generatie verder leven?'. Bonhoeffers bezinning op deze vraag gedurende zijn gevangenisjaren
Authors: Den Hertog G.C.
Published: September 2022

After ten years of life under Hitler, Dietrich Bonhoeffer writes that ‘the ultimately responsible question is how a coming generation is to go on living’. This article argues that the answer to this question is present in Bonhoeffer’s prison writings, letters, literary work and theological essays, and traces on how that answer directs his thought, and what it implies for the interpretation of his theological thinking during this period, including his letters on the ‘non-religious interpretation’ of the Gospel and the Christian tradition.
Análisis de la sostenibilidad de paisajes agropecuarios: aproximación conceptual y metodológica
Authors: Bustamante Zamudio Clarita , Redondo Johan Manuel , Roa Ortiz Santiago A. , Melo L. Sioux Fanny , Márquez Torres Martha Liliana , Lozano Castro Nelson Enrique , García-García Jeimy Andrea , Díaz Timoté Julián , Pereira María Fernanda , Torres Mauricio , Andrade Medina Olga del Pilar , Soto Agudelo Amanda Lucía
Published: September 2022

Esta obra responde a la necesidad de divulgar una forma de entender y analizar la sostenibilidad de los paisajes que incluya todas las categorías de usos agropecuarios, con el objetivo de que tenga un marco institucional propio. La concepción de sostenibilidad desarrollada en este libro se deriva de una construcción conceptual y metodológica, generada de manera concertada con instituciones de carácter nacional comprometidas con el desarrollo sostenible rural de Colombia.