bluuebunny/crossref_metadata_2025 huggingface dataset:
In situ photocatalytically enhanced thermogalvanic cells for electricity and hydrogen production
Authors: Wang Yijin , Zhang Youzi , Xin Xu , Yang Jiabao , Wang Maohuai , Wang Ruiling , Guo Peng , Huang Wenjing , Sobrido Ana Jorge , Wei Bingqing , Li Xuanhua
Published: July 2023

High-performance thermogalvanic cells have the potential to convert thermal energy into electricity, but their effectiveness is limited by the low concentration difference of redox ions. We report an in situ photocatalytically enhanced redox reaction that generates hydrogen and oxygen to realize a continuous concentration gradient of redox ions in thermogalvanic devices. A linear relation between thermopower and hydrogen production rate was established as an essential design principle for devices. The system exhibited a thermopower of 8.2 millivolts per kelvin and a solar-to-hydrogen efficiency of up to 0.4%. A large-area generator (112 square centimeters) consisting of 36 units yielded an open-circuit voltage of 4.4 volts and a power of 20.1 milliwatts, as well 0.5 millimoles of hydrogen and 0.2 millimoles of oxygen after 6 hours of outdoor operation.
M/F-theory as Mf-theory
Authors: Sati Hisham , Schreiber Urs
Published: July 2023

In the quest for mathematical foundations of M-theory, the Hypothesis H that fluxes are quantized in Cohomotopy theory, implies, on flat but possibly singular spacetimes, that M-brane charges locally organize into equivariant homotopy groups of spheres. Here, we show how this leads to a correspondence between phenomena conjectured in M-theory and fundamental mathematical concepts/results in stable homotopy, generalized cohomology and Cobordism theory [Formula: see text] : — stems of homotopy groups correspond to charges of probe [Formula: see text]-branes near black [Formula: see text]-branes; — stabilization within a stem is the boundary-bulk transition; — the Adams d-invariant measures [Formula: see text]-flux; — trivialization of the d-invariant corresponds to [Formula: see text]-flux; — refined Toda brackets measure [Formula: see text]-flux; — the refined Adams e-invariant sees the [Formula: see text]-charge lattice; — vanishing Adams e-invariant implies consistent global [Formula: see text]-fields; — Conner–Floyd’s e-invariant is the [Formula: see text]-flux seen in the Green–Schwarz mechanism; — the Hopf invariant is the M2-brane Page charge ([Formula: see text]-flux); — the Pontrjagin–Thom theorem associates the polarized brane worldvolumes sourcing all these charges.

In particular, spontaneous K3-reductions with 24 branes are singled out from first principles : — Cobordism in the third stable stem witnesses spontaneous KK-compactification on K3-surfaces; — the order of the third stable stem implies the 24 NS5/D7-branes in M/F-theory on K3.

Finally, complex-oriented cohomology emerges from Hypothesis H, connecting it to all previous proposals for brane charge quantization in the chromatic tower: K-theory, elliptic cohomology, etc. : — quaternionic orientations correspond to unit [Formula: see text]-fluxes near M2-branes; — complex orientations lift these unit [Formula: see text]-fluxes to heterotic M-theory with heterotic line bundles.

In fact, we find quaternionic/complex Ravenel-orientations bounded in dimension; and we find the bound to be 10, as befits spacetime dimension [Formula: see text].
Pediatric Primary Cutaneous Lymphoma in China: A Retrospective Study
Authors: Zhang Congcong , Jiang Yiqun , Xu Xiulian , Sun Jianfang , Chen Hao
Published: July 2023

Background: The incidence and clinical features of primary cutaneous lymphoma (PCL) tend to differ by age, gender, geographical, and racial variation. All-aged and adult groups of PCL in various regions have been well demonstrated and compared, while the research concentrating on pediatric PCL is rare, especially in Asian countries. Objective: The aim of this study was to investigate the clinical characteristics of PCL in pediatric population at a single center in China. Methods: We conducted a retrospective study of 101 pediatric cases with PCL, diagnosed at the Institute of Dermatology, Chinese Academy of Medical Sciences, from January 2010 to December 2021. Results: Mycosis fungoides (MF), accounting for 41.6% of the total cases, was the most common subtype in pediatric PCL, and the hypopigmented MF accounted for 47.6% of all the MF cases. Lymphomatoid papulosis and chronic active Epstein-Barr virus infection tied for second place with a proportion of 22.8%. Primary cutaneous anaplastic large cell lymphoma, subcutaneous panniculitis-like T-cell lymphoma, primary cutaneous peripheral T-cell lymphoma, rare subtypes and primary cutaneous B-cell lymphoma, respectively, accounted for 2.0%, 4.0%, 4.0%, and 3.0%. Most patients had favorable prognosis during the follow-up. Conclusion: The study suggested that MF was the most common subtype in pediatric PCL in China, and most types of pediatric PCL had favorable prognosis.
Effect of Tai Chi on knee pain and muscle strength in middle-aged and older adults with knee osteoarthritis: a randomized controlled trial protocol
Authors: Yue Hongyu , Li Yang , Ma Jianwen , Xie Chaoqun , Xie Fangfang , Cai Junhao , Fang Min , Yao Fei
Published: July 2023

Background

Knee osteoarthritis (KOA) is a common public health problem and a leading cause of long-term pain, decreased muscle strength, and even disability. Tai Chi has been proved effective and highly recommended for KOA management worldwide. However, little is known about its benefits on quadriceps strength which is closely associated with relieving knee pain. This trial is designed to evaluate the efficacy and safety of Tai Chi on knee pain and muscle strength in middle-aged and older adults with KOA.

Methods

A total of 100 participants will be randomly divided into a Tai Chi group (TC group) (1x/week for 12 weeks) and a control group with a health education and stretching program (1x/week for 12 weeks) with a follow-up period of 6 weeks. The primary outcome is the change of Western Ontario and McMaster Universities (WOMAC) pain subscale at week 12 compared with baseline. Secondary outcomes include WOMAC stiffness and function subscales, data from isokinetic dynamometry, gait analysis with electromyography (EMG), and a 36-item short form health survey (SF-36). The daily dose of pain-relieving medication will also be recorded. All adverse effects will be assessed by the Treatment Emergent Symptom Scale (TESS).

Discussion

We expect this randomized trial to evaluate the effectiveness of Tai Chi on relieving pain and increasing quadriceps strength in KOA patients. This protocol, if proven effective, will contribute to providing a promising alternative intervention for middle-aged and older adults with KOA.

Trials registration number

This trial has been registered in the China Clinical Trials Registry (registration number: ChiCTR2300069339).
DNA quantification, Purity and Integrity v1
Authors: L. Peredo Elena
Published: July 2023

We will use three complementary methods to asses DNA.
A recipe for extremely reproducible enrichment analysis v2
Authors: Ziemann Mark
Published: July 2023

Enrichment analysis is a popular computational biology technique for interpreting omics data, but typically these are conducted irreproducibly with web-based and graphical interface tools, which risks omitting important methodological information. To enable complete reproducibility, the analysis needs to be conducted non-interactively, recording the versions of all dependancies. This is achieved using an Rmarkdown script running inside a docker container. This allows all instructions to complete the workflow in a sequence, including parameters which sometimes are not described in methods sections. Rmarkdown and other literate programming approaches are useful for such workflows because the end result combines code, outputs (like charts and tables), together with free text, which can be used for extended descriptions of experiment design, input data, interpretation of results, etc. Using R allows to leverage the large ecosystem of bioinformatics software in CRAN and Bioconductor repositories. Containerisation with docker allows packaging of code, data and environment into a single reproducible unit. This means the workflow can be run on different types of computers (windows PC, Mac, server, cloud, etc) and yield the same result. This protocol also guides users through other best practices in computational research such as source control, documentation and data archiving. This protocol is designed for Linux users who want to modify and remix the provided templates to undertake their own enrichment analysis. It requires a moderate level of shell scripting, some knowledge about docker containers, and moderate R scripting. A step-by-step video guide series has been uploaded to YouTube: https://www.youtube.com/playlist?list=PLAAydBPtqFMXDpLa796q7f7W1HK4t_6Db
Barcoding protocol for microalgae v1
Authors: L. Peredo Elena
Published: July 2023

Here I describe two methods for barcoding microalgae. One starts with extracted DNA. In that case, I use Promega GoTaq, and so far, it has performed well. If I am only barcoding, I prefer using Phire Direct PCR. as it doesn't require DNA extraction. Both methods offer the possibility of using master mixes that include loading dye, which saves time and does not affect Sanger sequencing. Additionally, I use ExoSAP-IT as a cleaning method instead of a column-based kit. I am happy with the results, as I have successfully obtained sequences of nearly 1kb.
A Pragmatic Study on Seed Shape Classification and its Association among Seed Quality Attributes in Chickpea (Cicer arietinum L.)
Authors: Sivakumar Karthick Babu , Gautam Ashish , Singh Satvinder , Panwar Ravindra Kumar , Arora Anju , Verma Sanjay Kumar
Published: July 2023

Background: Seed shape in chickpea, a less known but not a trivial trait to study, as the possibility to include it in applied breeding aspect is yet to be deciphered. The present study mainly focuses on the study of seed shape classification and its interrelationship with seed quality parameters. Methods: The present study was conducted at the N.E. Borlaug Crop Research Centre, G.B. Pant University of Agriculture and Technology in Pantnagar, Uttarakhand. Seed shapes in chickpea were classified into distinct classes like angular, globular and owl headed types, using set of genotypes that constituted all the three seed shapes and corresponding hybrids obtained by crossing them. Result: The Codominance of radicle length and dominance nature of shape of chalazal end was observed in a definite pattern. Angular types were dominant over owl-head and globular types, whereas the globular type was dominant over owl-head type. Angular and globular types had low and high protein content respectively. Globular types would be a key to merge the bi-directionally acting seed traits like protein content and seed weight. From our observations seed shape can be a potential criteria to select for seed protein content. We made clear cut shape classification based on seed components, which could helps in seed shaped based selection in large populations.
Analiza dyskursu „Gazety Polskiej Codziennie” na temat osób LGBT+. Rozważania w kontekście kampanii wyborczej roku 2020
Authors: Piechocka Karolina
Published: July 2023

Jednym z głównych wątków kampanii wyborczej poprzedzającej wybory na urząd Prezydenta Polski w 2020 roku okazał się spór — określany przez wielu ludzi mianem ideologicznego — o kształt polskiej rodziny i prawa przysługujące osobom LGBT+. Celem niniejszego artykułu jest przeanalizowanie dyskursu prawicowo-konserwatywnej „Gazety Polskiej Codziennie” na temat członków społeczności queerowej w okresie od 5 lutego do 10 lipca 2020 roku. Odpowiedzi na pytania dotyczące sposobów kreowania wizerunku ludzi LGBT+ na łamach dziennika, uzyskane metodą analizy treści, pozwolą nie tylko krytycznie spojrzeć na wydarzenia z przeszłości, ale mogą też być prognozą tego, co wydarzy się podczas kampanii wyborczej do Sejmu i Senatu jesienią roku 2023. Nie jest bowiem wykluczone, że omawiana problematyka, w perspektywie poważnych problemów natury gospodarczo-ekonomicznej oraz wojny w Ukrainie, ponownie zdominuje przekaz kreowany przez polityków.
Preventive Effect of Alpha-pinene on Cisplatin-induced Kidney Injury by Oxidative Stress, Inflammation and Apoptosis via NF-κB Signaling Pathway
Authors: Tan Junhua
Published: July 2023

Introduction:

The chemotherapy medication cisplatin is highly effective and is used in treating a wide variety of cancers. Tumor resistance and dose-related severe side effects, including kidney and hearing damage and suppressed bone marrow function, limit its clinical utility. This study aimed to investigate the nephroprotective effect of alpha-pinene against cisplatin-induced nephrotoxicity in male albino Wistar rats.

Methods:

A total of 24 rats were divided into four groups containing six animals. Alpha-pinene (50 mg/kg) was administered orally for 14 days, and cisplatin (50 mg/kg) was given intraperitoneally for the last two consecutive days (13th and 14th day). Kidney function markers, lipid peroxidative markers, antioxidant status, inflammatory markers, and apoptotic gene expressions were analyzed. The cisplatin-induced rats significantly elevated kidney function markers, inflammatory markers, and pro-apoptotic genes in kidney tissues. Further, the antioxidant level/activities and antiapoptotic gene expression were significantly diminished in cisplatin-induced rats.

Results:

Pretreatment with alpha-pinene significantly decreased kidney function markers, inflammatory markers, and pro-apoptotic genes and increased antioxidant status and antiapoptotic genes.

Conclusion:

These findings provide the protective effect of alpha-pinene against CP-induced nephrotoxicity, as measured by potent antioxidant and antiapoptotic properties.
LiDAR Uncertainty Quantification for Topo-Bathymetric Earth Science using Generalized Polynomial Chaos Expansion
Authors: Wise Alexandra Katherine , Sacca Kevin , Thayer Jeffrey
Published: July 2023

Though precise, most LiDARs are vulnerable to position and pointing
errors as deviations from the expected principal axis lead to projection
errors on target. While fidelity of location/pointing solutions can be
high, determination of uncertainty remains relatively limited. As a
result, NASA’s 2021 Surface Topography and Vegetation Incubation Study
Report lists vertical (horizontal, geolocation) accuracy as an
associated parameter for all (most) identified Science and Application
Knowledge Gaps, and identifies maturation of Uncertainty Quantification
(UQ) methodologies on the STV Roadmap for this decade. The presented
generalized Polynomial Chaos Expansion (gPCE) based method has wide
ranging applicability to improve positioning, geolocation uncertainty
estimates for all STV disciplines, and is extended from the bare earth
to the bathymetric lidar use case, adding complexity introduced by entry
angle, wave structure, and sub-surface roughness.

This research addresses knowledge gaps in bathy-LiDAR measurement
uncertainty through a more complete description of total aggregated
uncertainties, from system level to geolocation, by applying a gPCE-UQ
approach. Currently, the standard approach is the calculation of the
Total Propagated Uncertainty, which is often plagued by simplifying
approximations (e.g. strictly Gaussian uncertainty sources) and ignored
covariances. gPCE intrinsically accounts for covariance between
variables to determine uncertainty in a measurement, without manually
constructing a covariance matrix, through a surrogate model of system
response. Additionally, gPCE allows arbitrarily high order uncertainty
estimates (limited only by the one-time computational cost of computing
gPCE coefficients), accurate representation of non-Gaussian sources of
error (e.g. wave height energy distributions), and direct integration of
measurement requirements into the design of LiDAR systems, by
trivializing the computation of global sensitivity analysis.
Gramática e Estilo
Authors: Guedes Paulo Coimbra
Published: July 2023

Gramática e estilo é um manual de redação que se ocupa do exame das frases que compõem os textos, isto é, não trata do aspecto discursivos nem do estrutural, que foram tratados em Da redação à produção textual (São Paulo, Parábola, 2009). Trata das dificuldades com que os escritores aprendizes se defrontam ao escreverem suas frases a partir do exame de frases que exemplificam tais dificuldades recolhidas de escritos produzidos por aprendizes tanto no Ensino Médio quanto no Superior, ao longo dos mais de cinquenta anos de militância do seu autor tanto no Ensino Médio quanto nos cursos de Jornalismo e Letras da UFRGS. O nome Gramática e estilo quer enfatizar que não se trata apenas de examinar, discutir e corrigir os erros das frases examinadas. Trata-se também de discutir o efeito estilístico dos recursos (palavras, orações, frases, parágrafos) construídos pelos aprendizes e orientá-los para que se tornem capazes de escolher os recursos – palavras, orações e frases – mais adequados para que obter os efeitos pretendidos. Não se trata apenas de acompanhar uma exposição sobre tais dificuldades, mas também de resolver os exercícios que acompanham cada uma das secções que abordam tais construções problemáticas. São sete capítulos: o primeiro examina os problemas gerais da língua escrita ao longo de sua história até a criação do texto, que se constituiu por frases compostas por palavras encadeadas. Nos capítulos seguintes, trata dos problemas desses encadeamentos e da pontuação a que se recorreu para viabilizá-los. Seguem-se o exame do papel desempenhado nesses encadeamentos pelo processo da coordenação e pelo da subordinação. Trata, a seguir ordem das palavras na frase e das frases no texto. Examina, então, os elementos presentes nas frases que são indicativos da natureza do texto, como, por exemplo, os tempos verbais em que elas andam, e o papel expressivo da ordem em que as frases se dispõem em relação umas às outras. Examina, então, textos exemplares pela adequação entre os seus objetivos e o seu modo de construírem-se para desenvolvê-los.
Conservation of Medicinal Plants in North Sumatra for Sustainable Use
Authors: Rahmawaty  , Abdul Rauf  , Arina Hafizah , Afifuddin Yunus
Published: July 2023

Indonesia is one of the countries with the most significant biodiversity globally, and one of the essential biodiversity is medicinal plants. To maintain the sustainability of medicinal plants, it is necessary to conserve medicinal plants. This activity aims to collect and preserve medicinal plants found in North Sumatra Province. The implementation method consists of several stages of activities: making a collection and conservation hut for medicinal plants, preparation of planting media, planting, arrangement of seeds for collection of medicinal plants. Collection/collection of medicinal plant seeds from various sources, Giving names of medicinal plant species, Inauguration, and socialization of therapeutic plant collection and conservation lodges. The partner in this activity is the Pondok Miri Asri farmer group located in Sei Semayang Village, Sunggal District, Deli Serdang Regency, North Sumatra Province. More than 90 types of medicinal plants have been collected from Sei Semayang Village, from the Miri Asri cottage farmer group, and several districts in North Sumatra Province. With the existence of a place to collect medicinal plants, it is hoped that it will be helpful for the community and can be used sustainably.
Kitab-Kitab Tafsir Dalam Pengajian Takmir Di Institusi Masjid Di Perlis: Kajian Tinjauan
Authors: Muhammad Lukman Mat Sin  , Khalilullah Amin Ahmad
Published: July 2023

The mosque institutions are important platforms in the studies and dissemination of religious knowledge. They serve as the nucleus in producing civilized Muslim communities that are able to appreciate the Quran and sunnah in life. Takmir class is one of the forms of knowledge study in mosque institutions throughout the state of Perlis which also emphasizes the study of tafsir. Through the tafsir studies delivered by a certified takmir teacher, correct and accurate understanding of the meanings of al-Quran al-Karim can be achieved in moving towards the true appreciation of al-Quran al-Karim in life. Therefore, this article will describe the tafsir books used in the study of tafsir by reviewing five district mosques in Perlis and analyzing the opinions of mosque congregations who attended the related lectures. This study uses qualitative methods in the form of interviews, observations and document analysis. The researcher conducted interviews and observations on five selected informants among the takmir teachers who taught at the mosque, while document analysis was used by analyzing the materials or sources of turath writing that had been collected. Findings of the study show that the effectiveness of tafsir lectures at mosque institutions in Perlis are at positive levels in terms of the selection of tafsir books and their suitabilities with the mosque congregation and the congregation's response to the tafsir books taught. It is hoped that this study can instill interest in the community to deepen the meaning of al-Quran al-Karim which is the main source of legislation in Islam.
A review of multi-omics data integration through deep learning approaches for disease diagnosis, prognosis, and treatment
Authors: Wekesa Jael Sanyanda , Kimwele Michael
Published: July 2023

Accurate diagnosis is the key to providing prompt and explicit treatment and disease management. The recognized biological method for the molecular diagnosis of infectious pathogens is polymerase chain reaction (PCR). Recently, deep learning approaches are playing a vital role in accurately identifying disease-related genes for diagnosis, prognosis, and treatment. The models reduce the time and cost used by wet-lab experimental procedures. Consequently, sophisticated computational approaches have been developed to facilitate the detection of cancer, a leading cause of death globally, and other complex diseases. In this review, we systematically evaluate the recent trends in multi-omics data analysis based on deep learning techniques and their application in disease prediction. We highlight the current challenges in the field and discuss how advances in deep learning methods and their optimization for application is vital in overcoming them. Ultimately, this review promotes the development of novel deep-learning methodologies for data integration, which is essential for disease detection and treatment.
Queers, Fears, and Peers
Authors: Simmons Jonathan
Published: July 2023

This chapter explores integrating LGTIQ themes and content into teacher education through three perspectives. First, the chapter offers the auto-ethnographic reflections of a queer teacher educator and some of the ways that they have grappled with their identity and being out and visible in the higher education setting. Next this chapter explores efforts made by this teacher educator to help pre-service teachers think about integrating LGTIQ history into their future classrooms. The chapter offers a framework for teachers to think about learning objectives as they plan and implement LGTIQ history lessons, including lessons that are considered as ‘queer representation lessons', ‘queer content lessons', and ‘queer lens lessons'. Finally, this chapter discusses efforts to create space on the program level to help pre-service teachers be prepared to work with and support LGTIQ students, colleagues, and families.
Network Pharmacology of Xian-Lian-Jie-Du Decoction in Ameliorating Colorectal Cancer
Authors: Zhao Ming-Xia , Song Cheng-Lin , Zhang Qin-Chang , Du Hao-Jie , Zhang Shu-Qiong , Shen Yu-Xian , Sun Yang , Cheng Hai-Bo , Lv Wen
Published: July 2023

Objective:

In this study, we screened for therapeutic targets of the Xian-Lian-Jie-Du decoction (XLJDD) for colorectal cancer (CRC) and explored the underlying mechanisms using network pharmacology techniques.

Methods:

Genes associated with CRC were collected from the GeneCards database. The names of the active compounds of XLJDD were used as keywords in the “chemical name” in the Traditional Chinese Medicine Systems Pharmacology (TCMSP) database to search the targets. The protein–protein interaction (PPI) network was constructed using Cytoscape 3.8.1. Gene Ontology functional enrichment and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses were performed to identify key target proteins.

Results:

A total of 234 XLJDD-related targets and 250 cross-targets between XLJDD and CRC were collected based on the TCMSP and HIT 2.0 databases. A PPI network constructed based on the STRING database revealed interactions for all 250 proteins. The network results revealed TP53, MYC, CCND1, AKT1, CASP3, and STAT3 as core potential targets. KEGG pathway analysis of the 250 potential XLJDD targets for CRC in the Metascape database was performed using RStudio software. The top 12 gene ratio aggregated analysis results were visualized in bubble charts. The interleukin (IL)-17 signaling pathway had the highest correlation with the tumor necrosis factor (TNF) signaling pathway.

Conclusions:

XLJDD may be effective in ameliorating CRC by controlling inflammatory factors related to the IL-17 and TNF pathways and targeting proto-oncogenes and tumor suppressor genes, including MYC, CCND1, CTNNB1, and TP53.
Non-dimensional Hydrodynamic Coefficients Determination of a Derived-Submarine Bare Hull Form
Authors: BUDAK Gökhan
Published: July 2023

The hull of the marine vehicle can be optimized based on the target one or more purposes. One of the most frequent purposes is the form optimization to obtain the most suitable form in terms of resistance. When it comes to energy efficiency, optimizing the vessel's form in terms of resistance means less fuel consumption. However, it is thought that the effect of the optimized form on other dynamics in the marine vehicle should also be investigated. Resistance coefficients were obtained for this purpose by constructing various bow and stern forms for a simple submarine form. The resistance coefficients of both the submarine and the form derived from this submarine were validated again in this study since different software programs were used in the previous study. These dimensionless resistance coefficients obtained for various velocities were compared to each other and the experimental data. Furthermore, the static drift analyses are performed to obtain the sway force and yaw moment at various attack angles. The dimensionless hydrodynamic coefficients, such as Y_v' and N_v’, have been calculated with fitting a curve to the values of sway forces and yaw moments. The non-dimensional hydrodynamic coefficients differences calculated for the submarine and derived bare hull are close to each other when compared in terms of maneuvering derivatives.
Instrumentos de avaliação funcional para classificação do risco de quedas em acidente vascular cerebral
Authors: Benatti Laís Cristina , Meneghetti Cristiane Helita Zórel
Published: July 2023

O Acidente Vascular Cerebral (AVC) é caracterizado por uma interrupção súbita do fluxo vascular por conta de isquemia ou hemorragia, podendo causar diversas incapacidades. O objetivo deste trabalho é realizar um levantamento bibliográfico dos principais instrumentos de avaliação funcional para classificação do risco de quedas em Acidente Vascular Cerebral. Trata-se de uma revisão sistêmica sobre os principais instrumentos de avaliação para classificação do risco de quedas em pacientes com AVC em artigos publicados em língua portuguesa e inglesa com buscas feitas nas seguintes bases de dados: Scientific Electronic Library Online (Scielo), Google Escolar, National Library of Medicine (MedLine e PubMed), Biblioteca Virtual em Saúde (BVS) e PEDro. O levantamento bibliográfico apresenta informações relevantes, uma vez que, ao utilizar instrumentos que classificam o risco de quedas em indivíduos com AVC, permite estabelecer estratégias terapêuticas direcionadas às necessidades funcionais. Constatou-se que os instrumentos mais citados e  utilizados para se verificarem os riscos de queda em pacientes com AVC são a Escala de Equilíbrio Funcional de Berg (EEFB) e o Time up and go (TUG).
Factores de riesgo de anemia ferropénica en lactantes de 6 meses en el centro materno infantil Miguel Grau. Chaclacayo. 2016 – 2019
Authors:   , Canchiz Sánchez Jackeline Roxana
Published: July 2023

OBJETIVOS: General: “Determinar los factores de riesgo de anemia ferropénica en lactantes de 6 meses en el Centro Materno Infantil Miguel Grau en Chaclacayo del 2016 al 2019. Específicos: Identificar la prevalencia de anemia ferropénica en lactantes de 6 meses en el Centro Materno Infantil Miguel Grau en Chaclacayo del 2016 al 2019; establecer los factores de riesgo maternos para la aparición de anemia ferropénica en lactantes de 6 meses en el Centro Materno Infantil Miguel Grau en Chaclacayo del 2016 al 2019; establecer los factores de riesgo perinatales para la aparición de anemia ferropénica en lactantes de 6 meses en el Centro Materno Infantil Miguel Grau en Chaclacayo del 2016 al 2019, establecer los factores de riesgo propios del lactante para la aparición de anemia ferropénica en lactantes de 6 meses en el Centro Materno Infantil Miguel Grau en Chaclacayo del 2016 al 2019.” MATERIAL Y MÉTODO: Explicativo. Tipo: Casos y Controles, retrospectivo. RESULTADOS: “La variable anemia materna en el tercer trimestre de gestación se presentó en el 46.7% de los casos y sólo en el 12.7% de los controles. Con un Chi cuadrado de 41.5 y p=0.00, teniendo ambas variables asociación significativa. Interpretamos por el Odd Ratio, que los lactantes cuyas madres tuvieron anemia durante la gestación tienen 6 veces más probabilidades de desarrollar anemia.” CONCLUSIONES: “Se estableció a la anemia materna como factor de riesgo para la presencia de anemia ferropénica en lactantes de 6 meses, en el periodo de estudio; con p=0.00 y OR=6 (IC 95% 3.38 – 10.75). La mejora del problema identificado contribuirá con el descenso de la prevalencia en lactantes, mejorando la salud de los menores.”
Colonic Perforation Secondary to Gallstone Impaction in the Sigmoid Colon
Authors: Gavriilidis Paschalis , Paily Abhilash
Published: July 2023

Introduction. Gallstone sigmoid ileus is a very rare manifestation of large bowel obstruction. Mainly, three conditions predispose the manifestation of the entity; in particular, an episode of cholecystitis causing cholecysto-colonic fistula; a large gallstone; and narrowing of the sigmoid colon secondary to diverticular disease or malignancy. Case Report. An 82-year-old man presented to the emergency department with a one-week history of severe constipation, tachypnoea, tachycardia, hypotension, and high lactate. Physical examination demonstrated cyanosed upper and lower extremities and palpation of the abdomen revealed signs of peritonism, abdominal distention, and guarding. Computerized tomography scan demonstrated perforation of the hollow viscus organ secondary to impaction of the large gallstone in the sigmoid colon. Laparotomy revealed sigmoid perforation and widespread feculent peritonitis. The patient underwent Hartmann’s procedure. After the intervention gave concerns regarding the patient’s haemodynamic stability, he was transferred to the intensive care unit. The patient passed away on the third postoperative day due to complications secondary to haemodynamic instability. Conclusions. Patients with early diagnosed uncomplicated sigmoid gallstone ileus can be managed with endoscopic mechanical lithotripsy. In case of failure, open or laparoscopic enterolithotomy can be applied. However, when patients present with complications, surgery should not be delayed. In our case, Hartmann’s procedure was an absolute indication due to sigmoid perforation and widespread feculent peritonitis.
Association between nonprescription use of nootropics and sleep quality in medical students
Authors: Alves de Azevedo Dênia , Turci Maria Aparecida , Castelo Branco Rocha Silva Guilherme , Cesar Piva Hugo , Túlio Silveira Sousa Gustavo , Sampaio Moura Alexandre
Published: July 2023

Objetivos: analisar a qualidade do sono de estudantes de medicina em uma universidade privada brasileira e sua associação com o uso não prescrito de nootrópicos (metilfenidato, lisdexanfetamina e modafinil). Métodos: a qualidade do sono foi analisada utilizando-se o questionário de Pittsburgh (PSQI). Considerou-se um questionário sociodemográfico para identificaçãopsicossocial dos participantes e uso de nootrópicos. Os resultados foram representados como média e desvio-padrão (para as variáveis quantitativas) ou frequência (para as qualitativas), e as associações foram analisadas pelo teste de qui-quadrado.Resultados: responderam ao questionário 362 alunos. Os níveis médios de PSQI global em estudantes com uso recente não prescrito de nootrópicos foi semelhante ao observado para estudantes que nunca usaram nootrópicos (7,76 vs. 7,73; p=0,96). A análise do PSQI por domínio específico também não mostrou diferença estatisticamente significativa. Observou-se que 23,6% das mulheres e 33,9% dos homens tiveram boa qualidade do sono, sendo essa diferença estatisticamente significativa (p=0,04). O uso de seis doses ou mais de bebida alcoólica esteve relacionado com níveis mais altos do PSQI (7,47 vs. 8,19; p=0,047). Alunos com qualidade do sono ruim apresentaram menor satisfação com a escolha profissional (OR = 1.84; IC95%= 1.09 - 3.11), menor percepção de aquisição de habilidades (OR = 1.96; IC95% = 1.16 - 3.31) e maior proporção de pensamentos relacionados a abandonar o curso (OR = 0,46; IC95% = 0,27 - 0,77). O uso recente e não prescrito de nootrópicos esteve  associado ao uso de maconha e ao desejo de abandonar o curso.
Pós-Graduação Lato Sensu: como alinhar as demandas regionais e a vocação das instituições de ensino superior?
Authors: Favretto Jacir , Echeveste Marcia Elisa Soares , Rodrigues Claudia Medianeira Cruz , Gumbowsky Argos , Miorando Bernardo Sfredo
Published: July 2023

Uma Instituição de Educação Superior (IES) deve desenvolver suas atividades e direcionar as ações de forma a atender a legislação educacional vigente, as diretrizes estabelecidas no seu Plano de Desenvolvimento Institucional e suas funções, atender as expectativas e demandas da região na qual se insere, visando o desenvolvimento regional. A estruturação da informação referente às demandas regionais é necessária para que a Instituição de Ensino Superior elabore e consolide seu Plano de Desenvolvimento Institucional e, consequentemente, seus Projetos Pedagógicos de Curso. Neste contexto, o objetivo deste artigo é apresentar um modelo de sistematização de informações que relacione as demandas regionais com os objetos de conhecimento das IES, para orientar a criação e a atualização de cursos de pós-graduação lato sensu. Entende-se que essas informações dizem respeito ao ambiente interno e externo à IES, tendo como condicionantes, por exemplo, a legislação educacional e profissional, infraestrutura e plano estratégico da IES, contextos social, político, cultural e geográfico, e expectativas das organizações locais.  Como principal resultado, o modelo habilita as IES a delinearem seus portfólios de objetos de conhecimentos associados aos cursos de pós-graduação lato sensu, facilitando o gerenciamento das informações para construção do Projeto Pedagógico desses cursos, contemplando a demanda regional e os objetos de conhecimentos a serem atendidos.
Профессиональная физическая подготовка будущего инженера
Authors: Васенков Н.В. , Шайдуллина А.Р.
Published: July 2023

В исследование рассмотрено понятие "профессиональная физическая подготовка будущего инженера", аргументированно содержание физического воспитание студентов для развития профессиональной физической подготовки личности у будущих инженеров. Модель понятия включает в себя уважение, ценностные ориентации личности, к своему состоянию организма, к занятиям физическими активностями и спортом, личностную потребность в физическом развитии. Знание, умение организовывать культурные нормы правильного образа жизни.
Индустрия люксовых брендов: вчера, сегодня и завтра
Authors: Куропаткина М.С.
Published: July 2023

Статья посвящена анализу люксовой индустрии в контексте мировых изменений. Цель исследования связана с изучением изменений в сфере тяжелого люкса в течение последних лет. Методом исследования был выбран вторичный анализ открытых российских и зарубежных источников. Отдельное внимание уделено перспективам развития рекламы и PR люксовых товаров. В ходе анализа были выявлены основные направления развития люксовых брендов как в экономической, так и в маркетинговой сферах.
Dziennikarstwo — kapitalizm — demokracja. Aktualność myśli Ludwika Krzywickiego
Authors: Rydlewski Michał
Published: July 2023

W artykule przypominam napisany 131 lat temu artykuł Ludwika Krzywickiego pt. Kapitalizm a dziennikarstwo. Polski socjolog, tworzący w paradygmacie marksistowskim, bezwzględnie, lecz z dużą poznawczą przenikliwością formułuje uwagi względem pola dziennikarstwa, na które wkracza oraz przejmuje kapitalizm. Ocena tego jest jednoznaczna: kapitalizm zabija dziennikarstwo przez między innymi wyzysk sił twórczych dziennikarzy, rezygnację z pogłębionej refleksji na rzecz dostarczania informacji sensacyjnych, uległość wobec wydawców i akcjonariuszy. Diagnozę Krzywickiego zestawiam z najnowszymi pozycjami opisującymi i diagnozującymi pole dziennikarstwa, i szerzej mediów, aby wskazać, że, po pierwsze, myśl polskiego badacza jest aktualna, co wiąże się z kapitalizmem jako formą nastawioną na zysk ekonomiczny, a po drugie, kapitalizm w jego neoliberalnej postaci zagraża demokracji.
The Role of Testosterone Level in Women with Osteopenia
Authors: Taha Muzahem Mohialdeen , Taha Ekhlass M. , Mohammed Suhayla K.
Published: July 2023

There is substantial data supporting the importance of both endogenous and exogenous estrogen in maintaining reproductive health and preventing chronic disease, androgens in women's health are rarely discussed. This is one of the first researches to investigate correlates of blood testosterone concentrations in women with osteopenia, in anticipation of the growing interest in the role of androgens in women's health. A 65 volunteer women were enrolled in the current study, they were divided into two groups, 35 postmenopausal women with osteopenia were in the first group, and the second group contained 30 postmenopausal women without osteopenia as a control. Blood samples were collected from all participants and analyzed for testosterone level, also demographic data were collected. The results showed that women with osteopenia have significantly low levels of testosterone as compared to control, the correlation analysis using postmenopausal women with osteopenia as a model showed a significant reversed correlation between testosterone and T score. Cluster analysis results illustrated that T-Score, testosterone and, duration of the postmenopausal were organized in one cluster, which means the three variables were associated with each other in most of the studied cases.  The second cluster included t-score, testosterone and, BMI. Whereas the age factor contributed to the third cluster. Testosterone levels were significantly associated with osteopenia, which could indicate the development of osteoporosis in post-menopause women. Testosterone results were organized in one cluster with T-score and, duration of the postmenopausal. So the three variables were associated with each other in most studied cases.
Волонтерский отряд кафедры микробиологии, вирусологии, иммунологии «Вакцина добра» как фактор профессионального воспитания будущего медицинского работника
Authors: Парахина О.В. , Медведева О.А.
Published: July 2023

В данной статье рассматривается роль волонтерского отряда кафедры микробиологии, вирусологии, иммунологии «Вакцина Добра» в профессиональном воспитании будущего медицинского работника.
Низковольтные гетеротиристоры InP для генерации импульсов тока длительностью 50-150 ns
Authors: Слипченко С.О. , Подоскин А.А. , Гаврина П.С. , Кириченко Ю.К. , Шувалова Н.В. , Рудова Н.А. , Капитонов В.А. , Лешко А.Ю. , Шушканов И.В. , Золотарев В.В. , Крючков В.А. , Пихтин Н.А. , Багаев Т.А. , Яроцкая И.В. , Светогоров В.Н. , Рябоштан Ю.Л. , Ладугин М.А. , Мармалюк А.А. , Симаков В.А.
Published: July 2023

Current switches based on low-voltage InP heterothyristors with a maximum blocking voltage of 20V were developed and studied. In current pulse generation mode, the efficient operation of InP heterothyristors with a low-resistance load in the form of a capacitor was demonstrated. It has been shown that the minimum turn-on delay time is about 6 ns at a control current amplitude of 60 mA. The possibility of generating current pulses with a duration of 53–154 ns and amplitudes of 38–130 A was demonstrated when the capacitor values were changed in the range of 56–1000nF.
In-memory Multibit Multiplication and Accumulation Based on an Automatic Pulse Generation Circuit
Authors: Bai Su , Guo Jiaqi , Xu Yaohua , Peng Chunyu , Wu Xiulong
Published: July 2023

Computing in-memory technology is a promising way of solving the
“memory wall” problem when processing large-scale data,accelerating
data processing, and improving energy efficiency. However, calculations
in the analog domain are limited in terms of accuracy and sensitivity to
process, voltage, and temperature (PVT) changes. In this study, we
proposed a computing in memory multiply-and-accumulate (CIM MAC) circuit
which could generate pulses automatically and which endows the
time-domain approach with a digital character. The MAC result was
reflected by the pulse edge and converted into the final digital output
using a dual-edge counter quantization circuit, improving the accuracy
of the MAC operation and reducing the difficulty of quantization. The
performance of the proposed CIM circuit was evaluated using a 28-nm
process. It could achieve 4-bit multiplication without errors with an
energy efficiency of 40.34 to 883.37 TOPS/W.
Prognostic Value of Red Blood Cell Distribution Width and D-Dimer in Diffuse Large B-cell Lymphoma: Systematic Review and Meta-analysis.
Authors: Rahchamani Maryam , Sedghi Mohammad , Hakimi Ali , Nejatianfar Mahdi , Javaheri Tohid , Tavakoli Reza , Ahmadi Ramtin , Azmi-Naei Nazanin , Kamandi Neda , Soleimanian AmirMohammad , Makarem Mansoureh , Sangani Saeid Zahmatkesh , Shavaleh Rasoul , Rahmani Kazem , Foogerdi Moloud
Published: July 2023

Background: The significant role of red blood cell distribution width
(RDW) and D-Dimer as prognostic factors in patients with some blood
malignancies has been reported recently. Aim: We designed and performed
a meta-analysis to investigate the prognostic roles of RDW and D-Dimer
in subjects with diffuse large B-cell lymphoma (DLBCL). Materials and
Methods: We systematically reviewed PubMed-Medline, SCOPUS, EMBASE, Web
of Science Core Collection, and Google Scholar up to 30 April 2023 to
look for publications on prognostic effects of RDW and D-Dimer in DLBCL
patients. For investigation of the associations between RDW and D-Dimer
with the overall survival (OS) and progression-free survival (PFS) of
the DLBCL cases, hazard ratio (HR) with 95% confidence intervals (CIs)
was used. Results: We included 13 eligible studies in the present
meta-analysis. The results of pooled analysis showed that increased
levels of RDW was related to poor OS (HR=2.01, 95% CI: 1.62-2.48, P
value<0.01) and poor PFS (HR=1.52, 95% CI: 1.24-1.85, P
value<0.01) among the DLBCL patients. On the other hand, a
significant relationship was found between increased D-Dimer and poor OS
(HR=2.30, 95% CI: 1.03-5.14, P value<0.05) of the DLBCL
patients as well. Conclusion: Our finding clearly confirmed that
elevated RDW levels and D-Dimer were associated with adverse OS and PFS
in DLBCL.
Allergy Burden in Sichuan, China: Investigating Prevalence, Patterns, and Population Attributable Risks among Children
Authors: Li Hepei , Li Xiang , Liu Yang , Zeng Yanyan , Zhou Xiaolin , Wan Yi , Luo Kai , Chen Binbin , Ma Jian , Xiao Xuelian
Published: July 2023

Background：Allergic diseases are increasing globally,
including in China. This poses challenges to public health. Our study
aimed to investigate allergens in children from Sichuan Province and
their impact on dermatitis, rhinitis, and asthma. Methods：This
retrospective study analyzed the medical records of 3204 pediatric
patients aged 0-9 years at XXX. Serum samples were collected and tested
using a microfluidic-based enzyme-linked immunoassay. The analysis
focused on detecting allergen-specific immunoglobulin E for 20 food
allergens and aeroallergens. Results：In this study, the
proportions of children allergic to at least one allergen varied across
different age groups. For children aged <1 year, 1-3 years,
and 3-9 years, the proportions were 40.40%, 68.54%, and 37.66%,
respectively. Boys showed a higher susceptibility to atopic allergies
compared to girls (P<0.001). The prevalence of both food
allergens and aeroallergens was high among the study participants. Among
the food allergens, egg white (52.25%) and cow’s milk (39.33%) were
the most prevalent, while Dermatophagoides pteronyssinus (41.88%) and
Dermatophagoides farina (35.23%) were the most commonly observed
aeroallergens. The intensity scores of food allergens decreased with
increasing age, while the intensity scores of aeroallergens exhibited
the opposite trend. The population attributable risk (PAR) of atopy for
dermatitis was lower in the 3-9 years age group (40.10%) compared to
younger children (<1 year: 63.40%; 1-3 years: 65.10%).
Conclusions：The prevalence of atopic allergies varies with age
and gender. Additionally, the intensity of food allergens and
aeroallergens shows an age-related pattern. The proportion of
dermatitis, rhinitis, and asthma that can be attributed to atopy remains
consistently high across all age groups. However, there are differences
in the population attributable risk (PAR) of atopy for dermatitis and
asthma among different age groups.
Ideology, humanness, and value. On Adorno’s Stravinsky
Authors: Tsetsos Markos
Published: July 2023

Theodor W. Adorno?s critique of Igor Stravinsky has itself been repeatedly
criticised. Following the same line, the present article takes as its point
of departure the philosophical anthropology of Helmuth Plessner, which
challenges the premises of Marxist anthropology, on which Adorno based his
critique of Stravinsky. Far from regressing to the inhuman and primitive,
Stravinsky?s music affirms, in historically adequate modern terms, the
constitutive reflectivity of the human embodied condition, thus becoming
more ?human?, i.e. meaningful and expressive, than Adorno could have even
conceived. Additionally, an account is provided of some groundbreaking
musical qualities that underpin the artistic value of Stravinsky?s music,
which Adorno also contested.
TUNDAAN LALU LINTAS TERHADAP TINGKAT PELAYANAN JALAN
Authors: Garini Ardya , Sriharyani Leni , Kurniawan Septyanto
Published: July 2023

Sejalan dengan pesatnya perkembangan kota, tuntutan lalu lintas yang semakin padat, dan permintaan masyarakat terhadap kendaraan yang semakin besar akan menambah kemacetan lalu lintas. Tidak seimbangnya jumlah lalu lintas dengan lebar efektif jalan, rendahnya tingkat pelayanan, pendeknya waktu hijau akan menyebabkan tundaan serta antrian lalu lintas pada persimpangan. Sebagaimana hal tersebut diatas, dicoba untuk melakukan analisa tundaan lalu lintas pada simpang bersinyal.

Studi ini menggunakan pendekatan dari MKJI 1997 (Manual Kapasitas Jalan Indonesia) dengan meninjau persimpangan “Jalan Diponegoro – Jalan Raden Intan”. Perolehan data dilapangan yaitu, Geometrik Jalan, Volume Lalu Lintas, Waktu Sinyal, dan Panjang Antrian. Setelah perhitungan dilapangan, didapat nilai tundaan rata-rata 45,52 detik dengan tingkat pelayanan type E. Hal ini menunjukan bahwa kinerja simpang pada Jalan Diponegoro – Jalan Raden Intan yaitu rendah. Untuk itu, perlu adanya solusi seperti : menutup jalan Jl. K.H Ahmad Dahlan yang akan keluar/ masuk ke Jl. Diponegoro, merencanakan ulang waktu sinyal, perlu adanya rekayasa lalu lintas pada simpang bersinyal Jl. Diponegoro – Jl. Raden Intan.