bluuebunny/crossref_metadata_2025 huggingface dataset:
Comparative evaluation of oral microflora adherence on modified tissue conditioners -- An in vitro study.
Authors: Demeri Farah , D Krishna Prasad , SHETTY VEENA , Shetty Shriya
Published: June 2021

Aims: To evaluate the effect of silver nanoparticle, itraconazole and a
combination of the two agents on the adherence of Candia albicans,
Streptococcus mutans and Enterococcus faecalis on acrylic and silicone
tissue conditioners. Materials and Methods: 40 pellets of Group 1 ( GC
Soft Liner) and 40 of Group 2 (Sofreliner) were fabricated. The pellets
were immersed in a solution of silver nanoparticles or itraconazole or a
1:1 ratio of the combination of the two medicaments. The amount of
biofilm formed was assessed by the ELISA reader. Results: A decrease in
adherence of Candida albicans was seen in acrylic and silicone-based
tissue conditioners when compared to the untreated control samples.
Silicone based tissue conditioner showed the least adherence of Candida
albicans when treated with 1:1 ratio of silver nanoparticles and
itraconazole. There was a statistically significant difference in
microbial adhesion between acrylic and silicone tissue conditioner
(p<0.001).Pellets treated with silver nanoparticles were
studied for adherence of Streptococcus mutans , Candida albicans and
Enterococcus faecalis. A statistically significant decrease in all three
microbial adherences was observed with this group. (p<0.001)
Conclusion: Silver nanoparticles and itraconazole are effective
antifungal and antibacterial agents that can potentially decrease
microbial colonization of Candia albicans , Streptococcus mutans and
Enterococcus faecalis on tissue conditioners. Clinical implications:
Silver nanoparticles and itraconazole when used will decrease biofilm
formation that will not only improve the overall health of the oral
cavity but also prevent denture stomatitis and diseases associated with
poor oral hygiene protocols. Keywords: Silver nanoparticles, tissue
conditioners, itraconazole, antimicrobial.
Analysis of COVID 19 Infection in Chronic Kidney Disease and Kidney Transplant Patients in Pandemic Hospital: What Has the Last Year Taught Us?
Authors: ay nurettin , Danis Ramazan , Kılıc Jehat , Altıntaş Derya Deniz
Published: June 2021

Objective: This study aims to investigate the mortality factors in
hemodialysis patients and kidney transplant patients with COVID-19
patients. Method: The demographic, clinic, laboratory, and radiologic
signs of the kidney transplant and hemodialysis patients diagnosed with
COVID-19 between 11 March 2020-11 March 2021 were evaluated. Results: To
this study, 72 hemodialysis (median age, 57.5 Q1-Q3:43-65;
female:36/50%) and 58 kidney transplant (median age, 44.5
Q1-Q3:28.75-55.25; female:21/36.2%) were included. Fifteen HD patients
(20.8%) died. To identify the independent predictors of in-hospital
mortality, multivariable logistic regression analyses were performed
using the variables in the univariate analyses including age, female
gender, diabetes mellitus, ferritin, d-dimer, albumin, CRP,
procalcitonin, dyspnea. Age (OR:1.12, 95% [CI]: 1.03-1.21,
p=0.004), and dyspnea (OR: 9,7 95% CI 1.80-52.2, p=0.008) were found to
be associated with in-hospital mortality. Nine (15.5%) of transplant
patients died. The median time from the beginning of symptoms to the
time of admission was 3 days (2-5). And this rate was 2 (2-3) and 5
(4-5.75) days, respectively, for patients followed up in our center and
the external centers (p<0.001). Although an increase in CRP,
ferritin, D-dimer levels, dyspnea, and bilateral involvement in CT
images was statistically significant in the univariate analysis, no
single factor was found to be related to mortality in multivariate
analysis. Conclusion: Both HD and renal transplant patients should be
followed closely. Early admission of HD and RT patients might be
life-saving when suspected. Early inclusion of these patients into the
vaccination program might reduce mortality. However, large-scale
prospective randomized studies are needed.
Stability analysis for neural networks with discrete and leakage time-varying delay systems with delay-range-dependence and delay-derivative-dependence
Authors: Liu Pin-Lin
Published: June 2021

The paper deals with the stability problem of neural networks with
discrete and leakage interval time-varying delays. Firstly, a novel
Lyapunov-Krasovskii functional was constructed based on the neural
networks leakage time-varying delay systems model. The delayed
decomposition approach (DDA) and integral inequality techniques (IIA)
were altogether employed, which can help to estimate the derivative of
Lyapunov-Krasovskii functional and effectively extend the application
area of the results. Secondly, by taking the lower and upper bounds of
time-delays and their derivatives, a criterion on asymptotical was
presented in terms of linear matrix inequality (LMI), which can be
easily checked by resorting to LMI in Matlab Toolbox. Thirdly, the
resulting criteria can be applied for the case when the delay derivative
is lower and upper bounded, when the lower bound is unknown, and when no
restrictions are cast upon the derivative characteristics. Finally,
through numerical examples, the criteria will be compared with relative
ones. The smaller delay upper bound was obtained by the criteria, which
demonstrates that our stability criterion can reduce the conservatism
more efficiently than those earlier ones.
Quality of life improvement after Obstructive Sleep Apnea treatment: Continuous Positive Airway Pressure versus Multilevel Transoral Robotic Surgery.
Authors: Iannella giannicola , Magliulo Giuseppe , Iacono Cristina Anna Maria Lo , Visconti Irene Claudia , Lechien Jerome , Perrone Tiziano , Maniaci Antonino , Cocuzza Salvatore , Luca Milena Di , Cammaroto Giovanni , Meccariello Giuseppe , Cannavicci Angelo , VITO ANDREA DE , Martone Chiara , greco antonio , Vincentiis Marco de , Ralli Massimo , Pace Annalisa , Gulotta Giampiero , Pelucchi Stefano , CIORBA Andrea , Corso Massimo Ruggero , Vicini Claudio
Published: June 2021

Objectives: The aim of this study has been to analyze effects on Quality
of Life (QoL) of the multilevel surgery for Obstructive Sleep Apnea
(OSA). Also, we have compared the impact on QoL of two different
treatments for patients with moderate to severe OSA such as CPAP and
transoral robotic surgery (TORS). Design: 67 OSA patients who underwent
multilevel robotic surgery and 67 OSA patients treated with CPAP were
enrolled in a Group 1 and Group 2 respectively. The Glasgow Benefit
Inventory (GBI) questionnaire has been administrated to all patients to
evaluate the changes in the QoL after the different OSA treatment.
Respiratory outcomes pre and post treatment were evaluated and compared.
Results: Group 1 showed a GBI total average value of +30.4, whereas the
group 2 a value of +33.2 . No statistical difference emerged (p=0.4).
General benefit score showed no difference between groups (p = 0.1).
Better values of social status benefit (p= 0.0006) emerged in CPAP
Group, whereas greater physical status benefit (p=0.04) was showed in
TORS Group. Delta-AHI (-23.7 ± 14.3 vs -31.7 ± 15.6; p = 0.001),
Delta-ODI (-24.5 ± 9.5 vs. -29.4 ±10.5; p = 0.001) showed better values
in CPAP group. Therapeutic success rate of Multilevel TORS Group was
73.1% and 91% in CPAP group (p = 0.01) respectively. Conclusion:
Multilevel TORS and CPAP have a positive effect in quality of life of
OSA patients. Greater social support has been reported in CPAP group and
better physical health status in TORS group.
Surgical repair of left-sided partial anomalous pulmonary venous connection associated with situs inversus totalis
Authors: Al-Dairy Alwaleed , Shammout Reem , habbal Raiean Al
Published: June 2021

Situs inversus totalis associated with partial anomalous pulmonary
venous connection is a very rare congenital heart malformation. Herein,
we describe successful surgical repair of the case of a 30-month-old
girl who had situs inversus totalis, partial anomalous pulmonary venous
connection , large atrial septal defect, and severe pulmonary
hypertension.
Phase equilibria of the Al-Co-Er system at 400°C and 600°C
Authors: Zheng L.-H. , Zhang L.-G. , Zhao F.-Y. , Liu L.-B. , Wang D. , Wu C.-J.
Published: June 2021

The 400?C and 600?C isothermal sections of the Al?Co?Er system were studied assisted with X-ray diffraction (XRD), scanning electron microscopy (SEM), and electron probe microanalysis (EPMA) techniques. 18 three-phase fields were identified in the 400?C isothermal section. The maximum solid solubilities of Al in Co3Er and Co2Er were 13.93 at.%, and 16.13 at.%, respectively whereas the maximum solid solubilities of Co in Al2Er, Al2Er3 and AlEr2 were 6.93 at.%, 6.65 at.%, and 6.49 at.%, respectively. The solid solution range of ? is from 22.22 at.% Al to 44.44 at.% Al while the 600?C isothermal section included 20 three-phase fields. The maximum solid solubilities of Al in Co17Er2 and Co7Er2 were 10.17 at.% and 10.24 at.%, respectively. The maximum solid solubilities of Co in Al2Er and Al2Er3 were 3.63 at.% and 2.01 at.%, respectively.
Use of the fractal dimension for porosity modification in aluminum foams manufactured using space holder particles
Authors: Reyes Christian , Béjar Luis , Pérez Luis , Aguilar Claudio , Carranza Juan , Carranza Luis , Alfonso Ismeli
Published: June 2021

The effect of space holder particles (SHP) fractal distribution on the porosity of aluminum foams manufactured by infiltration is studied in the present work. Physical models were used to estimate aluminum foam porosity, simulating SHP distribution for bimodal mixtures with different particle sizes and relative quantities. Results of these models were compared with mathematical models and the results obtained for experimental aluminum foams manufactured using a 332 Al-alloy base material and NaCl grains as SHP. Experimental foam structural characterization was carried out using image analysis to obtain porosity, density, wall thickness and fractal dimension, while mechanical characterization focused on the compressive Young modulus. Results show that it was possible to manufacture foams with different fractal porosities and a wide variety of unit cells, reaching a maximum of ? 68%. It was also found that pore wall thicknesses significantly decreased with the increase in the fine particles fraction. Besides, all the models presented a peak with a maximum porosity, whose values increased and shifted to low fine particles fraction with the increase in the sizes ratio. This behavior was also observed for the experimental foams with low particle size ratio. Nevertheless, for higher size ratios porosity showed an irregular behavior attributed to the mixing process.
Toll-like Receptor 2 (TLR2) Deficiency Abrogates Diabetic and Obese Phenotypes while Restoring Endothelial Function via Inhibition of NOX1
Authors: Guo Zhen , Zhang Yixuan , Liu Chang , Youn Ji Youn , Cai Hua Linda
Published: June 2021

We
have previously demonstrated a novel role of bone morphogenic protein-4 (BMP4)
in inducing NOX1-dependent eNOS uncoupling, endothelial dysfunction, and
inflammatory activation in type 2 diabetes mellitus (T2DM). However, it has
remained unclear as to how BMP4 activates NOX1 and whether targeting the new
mechanistic pathway revealed is effective in preserving endothelial function in
T2DM. Here we observed that BMP4 induced marked, time-dependent increase in
physiological binding between TLR2 and NOX1 in aortic endothelial cells, as
well as increased binding of TLR2 to NOXO1. In high-fat diet fed Tlr2-/- (TLR2 knockout) mice,
the body weight gain was significantly less compared to WT (wild-type) mice
both in males and females. The high-fat diet induced increases in fasting blood
glucose levels, as well as in circulating insulin and leptin levels, were
absent in Tlr2-/- mice.
High-fat
feeding induced increases in overall fat mass, and fat mass of different
pockets were abrogated in Tlr2-/- mice.
Whereas energy intake was similar in high-fat fed WT and Tlr2-/- mice, TLR2 deficiency resulted in higher energy
expenditure attributed to improved physical activity, which was accompanied by
restored skeletal muscle mitochondrial function. In addition, TLR2 deficiency
recoupled eNOS, reduced total superoxide production, improved H4B
and NO bioavailabilities in aortas and restored endothelium-dependent
vasorelaxation. Collectively, our data strongly indicate that TLR2 plays
important roles in the development of metabolic features of T2DM, and its
related endothelial/vascular dysfunction. Therefore, targeting TLR2 may
represent a novel therapeutic strategy for T2DM, obesity and cardiovascular
complications via specific inhibition of NOX1.
OPPORTUNITIES AND PERSPECTIVES OF IMMUNE NUTRITION IN PRETERM INFANTS
Authors: Dobryanskyy Dmytro , Dobryk D.S.
Published: June 2021

While mortality associated withrespiratory distress syndrome in premature infants hasbeen reduced, other morbidities associated with pretermbirth, including necrotizing enterocolitis (NEC) and sepsis,are becoming more relevant. Although the pathogenesisof these diseases remains incompletely defined andunderstood, one of the leading risk factors is the immaturityof the immune system, which determines the tendencyof premature infants to develop excessive inflammatoryresponse and disruption of the formation of "healthy" gutmicrobiota. Breastfeeding provides a protective effect dueto the wide range of immunologically active components ofthis unique product. Current data suggest that donor milk isthe best alternative to native breast milk, as the use of theformula is primarily associated with an increased risk ofNEC. The use of individual immunological components ofbreast milk, such as lactoferrin or immunoglobulins, doesnot reduce the incidence of this disease. At the same time,lactoferrin may reduce the incidence of late-onset sepsis.Pro- and prebiotics have better evidence for the preventionof these diseases, however, questions remain about thechoice of the most effective strains, dosage, duration,and safety of their use, especially in extremely prematureinfants with a birth weight <1000 g. Combined data fromexperimental and clinical studies indicate that human milkoligosaccharides may protect against NEC, however, morereliable evidence of their effectiveness is needed, as wellas the solution of technological problems associated withthe synthesis of individual oligosaccharides and their useas individual supplements. For today, clinical practices toensure mothers are optimally supported to express theirown breast milk in order to optimize breastfeeding, earlyenteral feeding, and faster increase in daily feeds are keynutritional methods to prevent NEC and late infections inpreterm infants.
20-year monitoring of physical developmental characteristics in school-age children and adolescents living in Kursk
Authors: Chernyh AM , Kremleva AS , Belova AI
Published: June 2021

The study was aimed to compare physical developmental characteristics in children and adolescents aged 7–18 living in Kursk for the years 2000–2001 and 2019–2020. The study was carried out in general educational institutions located in different urban areas of Kursk in 2000–2001 and 2019–2020. The standard anthropometric measurements, instruments and statistical methods were used. A total of 20,083 school-age children and adolescents were examined. The inclusion criteria were as follows: school-age children and adolescents staying at the educational institution at the time of the study, informed consent form properly completed, anthropometric measurements correctly performed. Statistical processing of the results was carried out using the Statistica 10.0 software package. The 20-year monitoring of physical development characteristics performed in school-age children and adolescents living in Kursk revealed the significant increase in height and body weight in all age and gender groups. The harmonious body acceleration manifestations associated with the muscle strength increase were observed in the context of sociomedical progress in Kursk.
Crecimiento postraumático y variables psicosociales en víctimas de violencia política
Authors:   Universidad de Concepción, Chile, Gómez Mauricio C. , García Felipe E. ,   Universidad de Concepción, Chile
Published: June 2021

Antecedentes: la dictadura militar chilena (1973-1990) dejó miles de víctimas entre afectados directos y familiares, quienes pudieron desarrollar diversas secuelas en su salud mental. Objetivos: el presente estudio buscó evaluar un modelo predictivo de crecimiento postraumático (CPT) que incluía la ideología política, el afrontamiento religioso y la rumiación, en víctimas de la violencia política durante la dictadura. Método: participaron 200 personas adultas reconocidas en el Programa de Reparación y Atención Integral de Salud (PRAIS), encargada de brindar apoyo a las víctimas directas de violaciones a los derechos humanos durante la dictadura, y a sus familiares. De ellos 104 son mujeres (52%) y 96 hombres (48%), en un rango de edad entre los 30 y 91 años. Se utilizaron como instrumentos el Inventario de Crecimiento Postraumático, la Escala Breve de Afrontamiento Religioso, la Escala de Rumiación relacionada con el Evento y la Escala de Ideología Política. Resultados: los principales resultados indicaron que el afrontamiento religioso positivo y la rumiación deliberada predijeron el CPT. La rumiación deliberada media parcialmente entre el afrontamiento religioso positivo y el CPT. Conclusión: se concluye que el afrontamiento religioso positivo y el procesamiento cognitivo deliberado favorecen los cambios positivos en víctimas directas de la violencia política y sus familiares. Ante esto, se refuerza la idea que las víctimas de estas violaciones logran crecer después de estas experiencias dolorosas.
Óvodáskori szájápolás - egy mikro kutatás tükrében
Authors: Baloghné Bakk Adrienn , Ponty Erika
Published: June 2021

Napjainkban vitatéma a megfelelő szájápolás, és ez így van a nevelési intézményekben, az óvodákban is. Kutatásunkban az óvodás korú gyermekek szájápolásával foglalkoztunk. Úgy gondoltuk, hogy szükséges e témában kutatásokat végezni, egy objektív helyzetet felvázolni, mivel az óvodai szakmai gyakorlatokon tapasztaltak szerint Magyarországon az óvodákban nagyon csekély szerepet játszik a személyi higiénia e formája. A ’United States Surgeon General’ 2009-es tanulmánya szerint a fogszuvasodás a leggyakoribb krónikus gyermekkori betegség az 5-17 évesek között, ami azt jelenti, hogy ötször gyakoribb, mint az asztma és hétszer gyakoribb, mint a szénanátha. Írásunkban röviden említést teszünk a kisgyermekek fogazatának lehangoló állapotról és gyakori betegségeiről. Bemutatjuk felmérésünk eredményeit, melyeket két megyében (Győr-Moson-Sopron és Vas) véletlenszerűen kiválasztott óvodákban dolgozó óvodapedagógusokkal készítettük (N=78). Összegezve megállapítottuk, hogy a vizsgált magyar óvodák többségében bár van fogmosás, de annak nem minden esetben tudnak megfelelő körülményeket biztosítani az intézmények. A fogmosás minőségi és elméleti szinten háttérbe szorul a nevelési programban, nagyon keveset foglalkoznak az óvodapedagógusok a szájápolás témakörével. A kutatás során felmerült a kérdés, elegendő figyelmet szentel-e az állam a prevenciós fogászatra a magyar óvodás gyermekek körében.
Use of propofol to induce food consumption by anorectic dogs following ovariohysterectomy
Authors: Papageorgiou Virginia , Ververidis Charalampos , Anagnostou Tilemachos , Savvas Ioannis , Kazakos George
Published: June 2021

OBJECTIVE

To determine whether IV propofol administration at a dose of 2 mg/kg (0.9 mg/lb) could induce food consumption by anorectic female dogs following elective ovariohysterectomy.

ANIMALS

51 healthy female dogs that failed to eat voluntarily when food was offered 6 hours after ovariohysterectomy.

PROCEDURES

In a randomized, blinded, controlled clinical trial, dogs received propofol (2 mg/kg; n = 31) or an equivalent volume of saline (0.9% NaCl) solution (20) IV 6 hours after ovariohysterectomy. Afterward, food was offered to the dogs and food consumption was reassessed. Pain, sedation, and stress were scored before and immediately after treatment.

RESULTS

27 of the 31 (87%) dogs in the propofol group consumed food immediately after administration of the assigned treatment, whereas only 1 of 20 (5%) dogs in the placebo group did. No difference in pain, sedation, or stress scores was identified between the 2 groups. Sedation scores for dogs in the propofol group increased immediately after propofol administration.

CONCLUSIONS AND CLINICAL RELEVANCE

Results suggested that food consumption following elective surgical procedures can be effectively induced in anorectic female dogs by IV administration of propofol at a dose of 2 mg/kg. (J Am Vet Med Assoc 2021;259:56–61)
Survival time for dogs with previously untreated, peripheral nodal, intermediate- or large-cell lymphoma treated with prednisone alone: the Canine Lymphoma Steroid Only trial
Authors: Rassnick Kenneth M. , Bailey Dennis B. , Kamstock Debra A. , LeBlanc Casey J. , Berger Erika P. , Flory Andrea B. , Kiselow Michael A. , Intile Joanne L. , Malone Erin K. , Regan Rebecca C. , Musser Margaret L. , Yanda Nathan , Johannes Chad M.
Published: June 2021

OBJECTIVE

To evaluate survival times for dogs with previously untreated, peripheral nodal, intermediate- or large-cell lymphoma treated with prednisone alone.

ANIMALS

109 client-owned dogs recruited from 15 institutions in the United States.

PROCEDURES

Dogs were treated with prednisone at a dosage of 40 mg/m2, PO, once daily for 7 days and at a dosage of 20 mg/m2, PO, once daily thereafter. Quality of life (QOL) was assessed by owners with a visual analog scale when treatment was started (day 0), 1 and 2 weeks after treatment was started, and every 4 weeks thereafter. The primary outcome of interest was survival time as determined by the Kaplan-Meier method. Factors potentially associated with survival time were examined.

RESULTS

Median overall survival time was 50 days (95% CI, 41 to 59 days). Factors associated with survival time included substage (a vs b) and immunopheno-type (B cell vs T cell). Owner-assigned QOL scores on days 0 and 14 were significantly positively correlated with survival time. When QOL score was dichotomized, dogs with day 0 or day 14 QOL scores ≥ 50 had significantly longer survival times, compared with dogs with day 0 or day 14 QOL scores < 50. No variables were predictive of long-term (> 120 days) survival.

CONCLUSIONS AND CLINICAL RELEVANCE

Results suggested that survival times were short for dogs with previously untreated, peripheral nodal, intermediate- or large-cell lymphoma treated with prednisone alone. Owner-perceived QOL and clinician-assigned sub-stage were both associated with survival time. Findings provide potentially important information for clinicians to discuss with owners of dogs with lymphoma at the time treatment decisions are made. (J Am Vet Med Assoc 2021;259:62–71)
Breed differences in the pharmacokinetics of orally administered meloxicam in domestic chickens (Gallus domesticus)
Authors: Souza Marcy J. , Gerhardt Lillian E. , Shannon Leah , Fortner Chelsey , Davis Rebecca , Condon Megan , Bergman Joan B. , Cox Sherry K.
Published: June 2021

OBJECTIVE

To determine the pharmacokinetics of meloxicam in Wyandotte hens and duration and quantity of drug residues in their eggs following PO administration of a single dose (1 mg of meloxicam/kg [0.45 mg of meloxicam/lb]) and compare results with those previously published for White Leghorn hens.

ANIMALS

8 healthy adult Wyandotte hens.

PROCEDURES

Hens were administered 1 mg of meloxicam/kg, PO, once. A blood sample was collected immediately before and at intervals up to 48 hours after drug administration. The hens’ eggs were collected for 3 weeks after drug administration. Samples of the hens’ plasma and egg whites (albumen) and yolks were analyzed with high-performance liquid chromatography.

RESULTS

Mean ± SD terminal half-life, maximum concentration, and time to maximum concentration were 5.53 ± 1.37 hours, 6.25 ± 1.53 µg/mL, and 3.25 ± 2.12 hours, respectively. Mean ± SD number of days meloxicam was detected in egg whites and yolks after drug administration was 4.25 ± 2 days and 9.0 ± 1.5 days, respectively.

CONCLUSIONS AND CLINICAL RELEVANCE

Compared with White Leghorn hens, meloxicam in Wyandotte hens had a longer terminal half-life, greater area under the plasma concentration-versus-time curve from time 0 to infinity, a smaller elimination rate constant, and a longer mean residence time-versus-time curve from time 0 to infinity, and drug persisted longer in their egg yolks. Therefore, the oral dosing interval of meloxicam may be greater for Wyandotte hens. Results may aid veterinarians on appropriate dosing of meloxicam to Wyandotte hens and inform regulatory agencies on appropriate withdrawal times. (J Am Vet Med Assoc 2021;259:84–87)
Effects of self-controlled knowledge of performance on motor learning and self-efficacy: A kinematic study
Authors: Makki Rezvaneh , Abdoshahi Maryam , Ghorbani Saeed
Published: June 2021

Study aim: To evaluate the effects of providing the learners with self-controlled knowledge of performance (KP) on motor learning and self-efficacy (SE) in a dart-throwing motor task.

Material and methods: The participants were thirty female university students who were divided into two groups including self-control and yoked groups. Participants performed five blocks of five trials in the acquisition phase, and retention and transfer tests of 10 trials one day later. Intra-limb coordination patterns (movement pattern), throwing scores, and SE (both movement pattern and movement outcome) were measured as dependent variables. Independent t test and one-way ANOVA with repeated measures were used as statistical tests.

Results: The self-controlled group performed significantly better than yoked group on movement pattern during the acquisition phase (F1,28 = 24.239, p = 0.001) and the retention test (t28 = –3.074, p = 0.007). However, there were no significant differences between groups in terms of throwing scores and SE during the acquisition, retention, and transfer phases (all p > 0.05).

Conclusion: Providing self-controlled KP can improve learning of movement pattern in the novices but do not necessary increase movement outcome or SE.
Managing patient aggression in healthcare: Initial testing of a communication accommodation theory intervention
Authors: Pines Rachyl , Giles Howard , Watson Bernadette
Published: June 2021

Patient-perpetrated workplace violence (WPV) in healthcare is common. Although communication skills trainings are helpful, they may be strengthened by having a theoretical framework to improve replicability across contexts. This study developed and conducted an initial test of a training framed by Communication Accommodation Theory (CAT) using longitudinal mixed-methods surveys of healthcare professionals in an American primary care clinic to increase their self-efficacy, patient cooperation, and use of CAT strategies to de-escalate patient aggression. Results of the intervention indicate that the CAT training significantly increased professionals’ efficacy and reported patient cooperation over time. Findings showed that those who reported using more of the five CAT strategies also reported situations that they were able to de-escalate effectively. This initial test of a CAT training to prevent WPV demonstrates promise for the applicability of CAT strategies to de-escalate patient aggression, and the need to scale and test these trainings in settings that experience high WPV levels.
La potestad sancionatoria de la Dirección del Trabajo
Authors: Rodríguez Reyes Isaías
Published: June 2021

Se analiza el escenario legal de la resolución de multa de la Dirección del Trabajo. En consideración a su actual regulación legal y administrativa, se revisa de forma crítica su origen, estructura y forma de impugnación. A partir de ello, nacen una serie de observaciones a la acción sancionatoria de la Dirección del Trabajo, en evaluación de las problemáticas y consideraciones dogmáticas propias del derecho administrativo sancionador.
La calificación de actividades de prestación como servicio público: revisión crítica desde criterios sustantivos aportados por el realismo jurídico
Authors: Herrera Orellana Luis Alfonso
Published: June 2021

El trabajo plantea críticas a la calificación por las autoridades como servicio público de ciertas actividades solo a partir de criterios formales y tópicos, argumenta a favor de considerar en tal proceso criterios sustanciales aportados por el realismo jurídico y demuestra la factibilidad de utilizar esos criterios al considerar el calificar o no como servicio público a actividades de prestación dirigidas a satisfacer necesidades públicas.
Early markers and predictors of cerebrovascular diseases in a group of young and middle-aged employees of the EMERCOM of Russia
Authors: Lomova I. P. , Kozhevnikova V. V. , Levashkina I. M. , Khutorov D. N. , Kindyashova V. V. , Makarova N. V. , Serebryakova S. V. , Tikhomirova O. V.
Published: June 2021

Introduction. Typical basis of chronic cerebral ischemia in young people is small vessel disease (SVD) diagnosed by micro-focal lesions and microstructural damage of cerebral white matter (WM), reduction of fractional anisotropy (FA) in diffusion tensor MRI (DT-MRI). Previous studies showed that increased dopplerographic pulsatility and resistivity indices in middle cerebral artery (MCA PI-RI) correlated with SVD manifestations and cognitive impairment in middle-aged and elderly patients. Aim – to determine early markers and predictors of asymptomatic SVD in young and middle-aged individuals without cognitive impairment. Materials and methods. 52 male employees of the EMERCOM, 47.3±7.6 years, without neurological or cognitive deficits were examined. Duplex scanning with MCA PI-RI calculation, MRI with WM damage assessment according to Fazekas scale, DT-MRI FA definition were completed. Results. All those examed showed MRI signs of SVD. Two groups were formed according to Fazekas: 0 points (n-38) and 1-2 points (n-14). The 2nd group showed higher MCA PI-RI (p<0.002 and p<0.05). Multivariate logistical regression analysis showed significant correlation of PI in MCA (OR: 2.33; 95% CI: 1.13- 4.81; p=0.02) with WM lesion according to Fazekas. The FA in cognitively important tracts was lower in group 2 (p<0,001). A stepwise multiple linear regression model revealed that the strongest predictors of FA reduction were PI and RI. The values of psychomotor speed and attention span were lower in group 2. Conclusion. MCA PI-RI are early markers of focal lesions and microstructural changes in WM and predictors of cognitive impairment in the young and middle-aged with asymptomatic SVD.
Informativity of blood flow distribution in the precerebral arteries for determining the hemodynamic significance of carotid stenosis
Authors: Semenyutin V. B. , Nikiforova А. А. , Aliev V. A. , Panuntsev G. К.
Published: June 2021

Introduction. Conventionally, hemodynamic significance of carotid stenosis is characterized with an increased peak systolic velocity up to 230 cm/s, which corresponds to 70 % carotid stenosis. This does not take into account changes of cerebral hemodynamics or collateral circulation, which can be determined by assessment of blood flow distribution in precerebral arteries. Aim – to evaluate blood flow redistribution in precerebral arteries in patients with critical carotid stenosis. Materials and methods. 40 patients (aged 49–80 y. o.) with critical carotid stenosis were studied (13 patients had 70–79 % stenosis, 11 patients – 80–89 %, and 16 patients – 90–99 % stenosis). Flow velocity index in precerebral arteries was determined with duplex scanning (Vivid e, USA), whereas linear blood flow velocity in intracranial arteries – with transcranial Doppler (MultiDop X, Germany). Results. In 60 % of patients, flow velocity index in ipsilateral carotid artery was reliably decreased (p<0.05). In 49 % of patients flow velocity index in contralateral carotid artery and blood flow velocity in contralateral anterior cerebral artery were reliably increased (p<0.05), as well as linear blood flow velocity in the contralateral anterior cerebral artery. Just in 39 % of patients flow velocity index in ipsilateral vertebral artery and linear blood flow velocity in ipsilateral posterior cerebral artery were increased (p<0.05). In 13 % of cases flow velocity index in the external carotid artery was increased (p<0.05). Conclusion. Thus, critical degree of carotid stenosis does not always indicate its hemodynamic significance. Flow velocity index distribution in precerebral arteries can be used as an additional criterion for assessing hemodynamic significance of carotid stenosis and, along with other indicators, should be taken into account when choosing treatment modality.
Causality of Fraud Detection
Authors: Muslim Muslim Darwis Lannai,
Published: June 2021

The purpose of this study is to examine the effect of experience, independence, implementation ethic and workload to fraud detection. Collecting data in this study using a questionnaire instrument with a sample of 52 auditors KAP in Makassar city using the saturated sampling technique. The analytical method used is the Partial Least Square (PLS) approach. The results of this study indicate that experience and implementation ethic had a positive and significant effect on fraud detection. While independence and workload had a positive but not significant influence on fraud detection.
Standar Operasional Prosedur (SOP) Izin Investasi Dalam Meningkatkan Minat Investor di Kota Depok
Authors: Sri Ernawati Siti Nurchalizah,
Published: June 2021

The research data processed is from the results of in-depth interviews or in-depth interviews for informants. The data sample was taken by snowball sampling. Data processing and analysis using SWOT. From the results of data processing, it was found that the internal and external matrices were compiled from the total score of the IFE (internal factor evaluation) and EFE (external factor evaluation) matrices which were valued (2.955 and 3.08). This can show that the position of the Standard Operating Procedure for investment permit procedures in increasing investor interest in the Depok City - West Java Investment and One Stop Integrated Services Service is in square II, which is this position shows that the Standard Operating Procedure for investment permits in increasing investor interest in the Department. Investment and One Stop Integrated Services for Depok City - West Java is growing and developing.
ДОСЛІДЖЕННЯ ПСИХОЛОГО-ПЕДАГОГІЧНИХ ОСОБЛИВОСТЕЙ ДИСТАНЦІЙНОГО НАВЧАННЯ
Authors: Колесник Галина
Published: June 2021

У статті розглядаються психолого-педагогічні чинники ефективності дистанційного навчання. Метою пропонованої розвідки є виявлення шляхів усунення психологічного дискомфорту учасників дистанційного навчання та наближення його до традиційних умов навчання. Автор наголошує, що ефективно організований дистанційний курс, спрямований на досягнення комфортного середовища, значною мірою мотивує студентів на досягнення результату та сприяє поліпшенню когнітивних успіхів. Встановлено, що лише інтерактивний зв’язок забезпечує комфортне спілкування учасників дистанційного навчання, формуючи віртуальну спільноту.
ОСНОВНІ ПРИНЦИПИ ВИКЛАДАННЯ ІНОЗЕМНОЇ МОВИ В АВІАЦІЙНИХ ЗАКЛАДАХ ОСВІТИ (середина ХХ ст. – початок ХХІ ст.)
Authors: Нечепорук Яна
Published: June 2021

У статті автор розглядає основні принципи викладання іноземної мови в авіаційній освіті із середини ХХ ст. до теперішнього часу. Стаття аналізує зміни методів викладання іноземних мов у технічних освітніх закладах залежно від цілей і задач, які ставила перед ними держава. В історії розвитку нашої країни були періоди, коли вивчення іноземних мов мало непріоритетний характер. 50-ті рр. відзначалися використанням граматико-перекладного методу як в загальноосвітніх, так і у вищих школах СРСР. 60-ті рр. та тогочасні реформи у сфері вивчення іноземних мов виявили певні недоліки попередників і наполягали на вивченні мови, використовуючи прямий метод, тобто уникаючи процесу перекладу під час навчання, намагатись не використовувати рідну мову. У 70–80-ті рр. підкреслювалась практична спрямованість методів викладання іноземної мови в льотних закладах освіти. Наразі, враховуючи стандартизацію та вимоги до сучасного авіаційного фахівця, в льотних навчальних закладах використовують велику кількість сучасних методів, що забезпечують активне володіння майбутніми авіаційними спеціалістами іноземною мовою як засобом формування і формулювання думок у галузі повсякденного спілкування та в галузі професійної діяльності.
ОСВІТА В УМОВАХ СЬОГОДЕННЯ: ВИКЛИКИ, РИЗИКИ, ПЕРСПЕКТИВИ
Authors: Чубінська Наталія
Published: June 2021

У статті зроблена спроба визначити цілі та завдання освіти в умовах інформатизації, глобалізації, інтеграції суспільного простору. Визначено, що повноцінне функціонування суспільства та освіти у ньому передбачає розширення рівня духовної, культурної, економічної, політичної та соціальної свободи особистості; розуміння рівня відповідальності людини за власне життєтворення; усвідомлення колективної відповідальності за зміни як у суспільному співжитті, так і в природі тощо.
ФОРТЕПІАННІ СОНАТИ № 1 І 2 ВАСИЛЯ БЕЗКОРОВАЙНОГО З ПОЗИЦІЙ ТОНАЛЬНИХ І ФОРМОТВОРЧИХ ОСОБЛИВОСТЕЙ
Authors: Герега Марія
Published: June 2021

У статті здійснено спробу виявити тональні та формотвірні особливості сонат Василя Безкоровайного та і їх дидактичний потенціал. Констатовано, що сонатні жанри в доробку композитора є художньо і дидактично вартісними зразками національного педагогічного репертуару. На їх прикладі можливе зіставлення класичної сонатної циклічної структури з численними індивідуально-трактованими модифікаціями і рисами фольклорних та побутових жанрів національного музичного мистецтва. Матеріал сонат з огляду на виконавські завдання (звукотворчі, стильові, жанрові, фактурні) цікавим є прикладом українського дидактичного репертуару сміливого трактування форми і тонального плану, становить добре підґрунтя для розвитку тонально-гармонічного мислення, ритмічних труднощів, пластичного мелодичного голосоведення інтервальними смугами, діалогічних перекличок далеких регістрів, різних типів акордової техніки.
ВКЛЮЧЕННЯ ДІТЕЙ З ОСОБЛИВИМИ ОСВІТНІМИ ПОТРЕБАМИ У СИСТЕМУ СОЦІАЛЬНИХ ВІДНОСИН ЗАСОБАМИ АРТ-ТЕРАПІЇ
Authors: Єрьоміна Лілія , Забела Яна
Published: June 2021

У статті порушено актуальну проблему сьогодення, що пов’язана з ситуаціями кризового стану, а саме – з соціалізацією дітей з особливими освітніми потребами. Автори визначають арт-терапію як могутній чинник особистісного розвитку, що сприяє успішному входженню особистості дитини у систему соціальних відносин. Завдяки аналізу наукових поглядів автори публікації зазначають, що саме завдяки арт-терапії можна змінити стереотипи поведінки, підвищити адаптаційні здібності, знайти компенсаторні можливості такої дитини і в кінцевому підсумку – успішно інтегрувати її у систему соціальних відносин.
СЦЕНІЧНА ДІЯЛЬНІСТЬ ЗОЇ ХРИСТИЧ У КОНТЕКСТІ РОЗВИТКУ ВОКАЛЬНОГО МИСТЕЦТВА УКРАЇНИ
Authors: Кліш Ірина
Published: June 2021

У статті розкривається конкурсна, концертно-виконавська і педагогічна, діяльність української співачки Зої Христич (сопрано), народної артистки України, солістки Київського театру опери та балету імені Т. Г. Шевченка. Висвітлюється широка палітра її участі у міжнародних вокальних конкурсах у Женеві (Швейцарія, 1956, диплом І ступеня), Відні (Австрія, 1959, перша премія і золота медаль), Тулузі (Франція, 1962, срібна медаль і звання лауреата), Софії (Болгарія, 1963), всесвітньому фестивалі демократичної молоді і студентів у Відні (1959). Подається опис її концертних виступів і оперних спектаклів, розкривається репертуар співачки і значення її творчості у розвитку музичного мистецтва України другої половини ХХ ст.
ВОКАЛЬНО-ХОРОВИЙ СПІВ ЯК ОЗДОРОВЧЕ МИСТЕЦТВО У КОНТЕКСТІ РОЗВИТКУ ТЕОРІЇ І ПРАКТИКИ МУЗИЧНОЇ ОСВІТИ
Authors: Заболотний Іван
Published: June 2021

У статті висвітлюється вокально-хоровий спів як оздоровче мистецтво у контексті розвитку теорії і практики музичної освіти. Актуалізується твердження щодо досліджень впливу вокально-хорового співу на людину, які ґрунтується на тому, що фізіологічний стан має оздоровчий ефект. Узагальнюючи вищевикладене, можемо стверджувати, що вокально-хоровий спів спрямований на профілактику захворювань, корекцію і реабілітацію здоров’я студентської молоді.
КОМПЕТЕНТНІСНИЙ ПІДХІД У ПІДГОТОВЦІ ФАХІВЦІВ З МАРКЕТИНГУ У НАУКОВОМУ ДОРОБКУ А. ПЕЙНА
Authors: Кравченко Тетяна
Published: June 2021

У статті здійснено аналіз наукової праці “Маркетинг відносин для отримання конкурентних переваг завоювання і утримання клієнтів” (авторський колектив під керівництвом А. Пейна). Виявлено, що автори виокремили компетенції, які сприяють формуванню конкурентоспроможності фахівця з маркетингу: діагностичні, аналітичні та прогностичні, компетенція соціальної комунікації, компетенції моделювання, проектування, прогнозування, комунікативна і перцептивна компетентність. Підкреслено, що продуктивними засобами формування умінь можуть виступати проектна діяльність, розв’язання завдань, розбір проблемних ситуацій, реалізація різних професійно-орієнтованих елементів освітньої діяльності, а також моделювання проблемних економічних, ринково орієнтованих ситуацій. Зроблено висновок, що компетентнісний підхід має значний потенціал і є платформою, яка може об’єднати і комплексно реалізувати різні напрацювання у сфері активного, розвиваючого, діяльнісного навчання.
Scientific support of border activity
Authors: Shumov Vladislav , Girnik Evgenij Sergeevich , Senichenkov Pavel Dmitrievich
Published: June 2021

The object of this research is the border activity, while the subject is the science of border activity – borderology. The article consists of five sections. The first section views border activity as a system of preventive (border prevention and deterrence), security and control (border patrol, border search), and defense-militant measures (special activity, combat activity, operational actions). The second and third sections give detail description to these measures, as well as the typical stages of the cycles of activity. The fourth section is dedicated to description of the structure of borderology – the system of knowledge on ensuring border security, state c of border organizations, preparation and conduct of border activity, and its all-round provision. The fifth section provides a systemic formulation of principles of border activity. Within the framework of development of the concept of “border management system”, the author considers the border activity as a system of measures aimed at ensuring national security in the borders. The science of border activity includes the following disciplines: border art (border policy, border operational art, border tactics), border history, border statistics, mathematical theory of managing border security, legal framework of border security and border activity, philosophy of border security, psychology and sociology of border activity, theory of border training and education, theories of all-round support of border activity, theory of development, application of technical and special means of border activity.   
The Question of State-Sponsored Terrorism: Investigation of ASALA and JCAG in the Light of Available CIA Documents
Authors: Kürkçü Burak
Published: June 2021

After a careful investigation of available archival documents of the Central Intelligence Agency (CIA) and the U.S. State Department, this paper questions the state sponsoring of the terrorist operations of the Armenian Secret Army for the Liberation of Armenia (ASALA) and the Justice Commandos of the Armenian Genocide (JCAG). An investigation of the documents ascertains that state support for ASALA is identified by the CIA; however, knowledge about JCAG has remained in the dark due to its extreme clandestineness. In this respect, other than the support of local Armenian communities, this paper traces the fingerprints of the Soviet Union, Syria, Iran, and Libya behind the violent acts of ASALA despite their discreet and covert sponsoring. Furthermore, the tolerance shown by France and Switzerland towards the attacks of ASALA and JCAG gives the impression that the terrorist attacks conducted by Armenian terrorism attracted a certain level of sympathy among Western European governments, as long as their violent acts did not target non-Turkish victims.
Symptomatic Chiari type 1 malformation associated with acromegaly: A case report
Authors: Aoki Takuma , Umebayashi Daisuke , Tatsuzawa Kazunori , Hashimoto Naoya
Published: June 2021

Background:

Here, we report a patient who presented with both symptomatic acromegaly and symptomatic Chiari I malformation (CM1) with a C2-T5 syrinx.

Case Description:

A 63-year-old female presented with bilateral arm dysesthesias and back pain. For approximately the past 30 years, she had chronic signs of acromegaly (i.e. an enlarged forehead, jaw, and nose, and enlarged hands and feet). When the cervical magnetic resonance showed a CM1 (tonsillar herniation) with C2-T5 syringomyelia, she underwent foramen magnum decompression and C1 posterior arch resection. Postoperatively, she was asymptomatic. The added finding of a growth hormone (GH)-producing pituitary lesion was treated medically with endocrine therapy, as she had incidentally required surgery/chemotherapy for a newly diagnosed colon cancer.

Conclusion:

Symptomatic CM1, syrinx, and acromegaly may occur together. Appropriately treatment may include a suboccipital decompression, and C1 arch resection surgery, followed by either surgical or medical treatment for the GH-producing pituitary adenoma.
Severe hypotension with loss of motor evoked potentials during cervical surgery prompting immediate cardiovascular resuscitation
Authors: Kim Daniel C. , Boyd Ethan J. , Boyd Thomas A. , Granger Hannah E. , Menger Richard P.
Published: June 2021

Background:

Intraoperative neuromonitoring (IONM) is a well-established adjunct to spinal surgery to ensure safety of the neural elements.IONM has extremely high sensitivity and specificity for impending neurologic damage. In very rare instances, hypoperfusion of the cord may lead to a loss of IONM modalities that may be reversed if blood pressure issues responsible for the drop out of potentials are immediately addressed.

Case Description:

The authors describe a case in which IONM documented hypoperfusion of the cord intraoperatively due to hypotension. Recognition of this problem and reversal of the hypotension resulted in normalization of postoperative function.

Conclusion:

The use of IONM allowed for quick recognition of an impending neurological insult during spinal deformity surgery. Prompt response to signaling changes allowed for the correction of hypotension and favorable neurologic outcome.