bluuebunny/crossref_metadata_2025 huggingface dataset:
Consensus-based proposal for forgoing dialysis therapy in Japan
Authors: Okada Kazuyoshi
Published: September 2022

The Japanese Society for Dialysis Therapy published a proposal in 2014 and revised it to Shared Decision Making for the Initiation and Continuation of Dialysis: A Proposal from the Japanese Society for Dialysis Therapy in 2020 to strictly adhere to guidelines of the Ministry of Health, Labour and Welfare, because forgoing life-sustaining treatment to respect the will of patients in end-of-life care is not stipulated by law in Japan. The revised proposal describes the process of providing information about renal replacement therapy, the natural course of end-stage kidney disease, and conservative kidney management (CKM), the conditions when providing CKM information to be considered by healthcare teams, the process of providing information about CKM if patients with decision-making capacity or families of patients without decision-making capacity wish to make the decision to forgo dialysis, the process of shared decision making for choosing CKM, and the importance of performing advance care planning (ACP) with patients and their families for making advance directives, etc. We need to promote ACP and to establish the content and practice of palliative care for patients after choosing CKM in collaboration with home-cased care doctors.
Comparative transcriptional analysis and identification of hub genes associated with wing differentiation of male in Aphis gossypii
Authors: HUANGFU Ningbo , SHI Qingyu , CHEN Lulu , MA Xiaoyan , ZHANG Kaixin , LI Dongyang , WANG Li , ZHU Xiangzhen , JI Jichao , LUO Junyu , CUI Jinjie
Published: September 2022

Background

Aphis gossypii Glover (Hemiptera: Aphididae), a worldwide polyphagous phloem-feeding agricultural pest, has three wing morphs (winged parthenogenetic female, gynopara, and male) in the life cycle. The exclusive males could fly from summer hosts to winter hosts, which are essential for gene exchanges of cotton aphid populations from different hosts or regions. However, the molecular mechanism of wing differentiation of male in A. gossypii remains unclear.

Results

Morphological observation of male A. gossypii showed that there is no distinct difference in the external morphologies of the 1st and 2nd instar nymphs. The obvious differentiation of wing buds started in the 3rd instar nymph and was visible via naked eyes in the 4th instar nymphal stage, then adult male emerged with full wings. According to morphological dynamic changes, the development of wings in males were divided into four stages: preliminary stage (the 1st instar to 2nd instar), prophase (the 3rd instar), metaphase (the 4th instar), anaphase (the 5th instar). Results of feeding behavior monitoring via EPG (electrical penetration graph) technology indicated that although the male cotton aphids had strong desire to feed (longer duration of C 55.24%, F 5.05% and Pd waves 2.56%), its feeding efficiency to summer host cotton was low (shorter E1 3.56% and E2 waves 2.63%). Dynamic transcriptome analysis of male aphid at 5 different developmental periods showed that in the 3rd instar nymph, the number of up-regulated DEGs was significant increased, and time-course gene transcriptional pattern analyses results also showed that numerous genes categorized in clusters 3, 5, and 8 had the highest expressed levels, which were consistent with morphological changes of wing buds. These results indicate that the 3rd instar nymph is the critical stage of wing bud differentiation in males. Furthermore, through pathway enrichment analysis of DEGs and WGCNA, it revealed that the neuroactive ligand-receptor interaction, Ras signaling pathway, dopaminergic synapse, circadian entrainment and the corresponding hub genes of PLK1, BUB1, SMC2, TUBG, ASPM, the kinesin family members (KIF23, KIF20, KIF18-19) and the novel subfamily of serine/threonine (Aurora kinase A and Aurora kinase B) probably played an important role in the critical stage of wing bud differentiation.

Conclusion

This study explored morphological changes and genes transcriptional dynamics males in cotton aphid, revealed the phenomenon of low feeding efficiency of winged males on summer host cotton, and identified key signaling pathways and potential hub genes potentially involved in wing bud differentiation of male in A. gossypii.
Aqueous extracts from indigenous plant in Burkina Faso with bio-herbicide properties to reduce Striga hermonthica (Del.) Benth propagation
Authors: Sawadogo/Ilboudo Tinkoudougou Cathérine , Yonli Djibril , Sourabie Soumaïla , Zerbo Patrice , Traoré Hamidou , Boussim Joseph Issaka
Published: September 2022

Background

The genus Striga includes 11 parasitic plants species of food crops in at least 50 African countries. Striga hermonthica (Del.) Benth. is a major biotic constraint to the cereal crops production in Africa. It is the most widespread species in fields in Burkina Faso and grows on all types of soil inducing losses estimated at 35–40% on sorghum and millet. The substantial reductions in yield caused by S. hermonthica contribute significantly to an insufficient food supply for the populations in the area.

Methods

This study aims to identify local plants with bio-herbicidal properties for the management of S. hermonthica. The inhibiting and stimulating effect of aqueous extracts from 13 local plant species on the germination of S. hermonthica seeds was assessed in vitro.

Results

The aqueous extracts from the leaves of Azadirachta indica A. Juss, Jatropha curcas L., Jatropha gossypiifolia L., Lawsonia inermis L. and those from the leafy stems of Cassia obtusifolia L., Crotalaria retusa L., Phyllanthus amarus L. completely inhibited germination of Striga. Five other plant extracts significantly stimulated germination, of which the highest germination rate (60%) was recorded with the extract from Euphorbia hirta L. leafy stems.

Conclusions

The plant extracts thus constitute an ecological avenue for S. hermonthica control. Further experiments could lead to the formulation of bio-herbicides against the parasitic plant to improve cereal production while limiting environmental pollution.
Design and flow field analysis of impregnated diamond bit for seafloor drill in soft-hard interlaced strata
Authors: Wang Jialiang , Chen Chen , Qian Dilei , Peng Fenfei , Yu Mengfei , Sun Yang , Peng Deping
Published: September 2022

According to the seafloor drill working conditions and the complex formation characteristics of the seafloor, this paper aims to improve the adaptability of the diamond bit to the formation and the coring quality. The cutter tooth design scheme of the impregnated diamond bit is proposed, and Fluent analyzes the flow field of drilling fluid at the bottom hole. The results show that the cone cutting tooth bit with the primary and assistant nozzles can directly avoid 85.33% drilling fluid flushing core and reduce the disturbance of drilling fluid to the core samples. The water passage structure of the bit is reasonable, and the upward return velocity of the drilling fluid can be stabilized between 0.7 and 1.8 m/s, which meets the requirements of the upward return of cuttings in seabed strata, and has a good hole wall protection performance. Based on the bottom-jet diamond bit, the assistant nozzles are added. The drilling fluid of the assistant nozzles can better cover the bit crown, conductive to cooling the bit crown. The drilling fluid of the main nozzles can timely up-return along the outer annulus hole wall, conducive to the up-return of the cuttings with drilling fluid. This study can extend existing designs of a seafloor coring bits and bottom hole flow field analysis methods.
Intraoperative Blood Pressure and Long-Term Neurodevelopmental Function in Children Undergoing Ambulatory Surgery
Authors: Ing Caleb , DeStephano David , Hu Tianheng , Reighard Charles , Lackraj Deven , Geneslaw Andrew S. , Miles Caleb H. , Kim Minjae
Published: September 2022

BACKGROUND:

Some studies have found surgery and anesthesia in children to be associated with neurodevelopmental deficits, but specific reasons for this association have not been fully explored. This study evaluates intraoperative mean arterial pressure (MAP) during a single ambulatory procedure in children and subsequent mental disorder diagnoses.

METHODS:

A retrospective observational study was performed including children ≥28 days and <18 years of age with intraoperative electronic anesthetic records between January 1, 2009, and April 30, 2017, at our institution. Eligible children were categorized based on their mean intraoperative MAP relative to other children of the same sex and similar age: category 1 (very low): children with mean intraoperative MAP values below the 10th percentile, category 2 (low): mean MAP value ≥10th and <25th percentiles, category 3 (reference): mean MAP value ≥25th and <75th percentiles, category 4 (high): mean MAP value ≥75th and <90th percentile, and category 5 (very high): mean MAP value ≥90th percentile. International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9) and ICD, Tenth Revision, Clinical Modification (ICD-10)-coded mental disorders were identified in hospital and outpatient claims, with a median duration of follow-up after surgery of 120 days (interquartile range [IQR], 8–774.5 days). Cox proportional hazards models evaluated the hazard ratio (HR) of time to first mental disorder diagnosis associated with intraoperative blood pressure category between the end of surgery and censoring, with the primary analysis adjusting for demographic, anesthetic, comorbidity, and procedure-type variables as potential confounders.

RESULTS:

A total of 14,724 eligible children who received general anesthesia for a single ambulatory surgical procedure were identified. After adjusting for all available potential confounders, when compared to the reference, there were no statistically significant differences in mental disorder diagnosis risk based on intraoperative mean MAP category. Compared to reference, children in the very low and low blood pressure categories reported HRs of 1.00 (95% confidence interval [CI], 0.74–1.35) and 1.10 (95% CI, 0.87–1.41) for a mental disorder diagnosis, respectively, and children in the high and very high categories reported HRs of 0.87 (95% CI, 0.68–1.12) and 0.76 (95% CI, 0.57–1.03), respectively.

CONCLUSIONS:

Presence in a predefined mean intraoperative MAP category was not associated with subsequent mental disorder diagnoses within our follow-up period. However, the limitations of this study, including uncertainty regarding what constitutes an adequate blood pressure in children, may limit the ability to form definitive conclusions.
A Growing Transparency in Medicine
Authors: Nathan Naveen
Published: September 2022

The provision of health services has been transforming from a largely top-down, paternalistic model into a construct in which patients play a substantive role in decision making over their care. Two articles in this month’s issue of Anesthesia & Analgesia and an accompanying editorial address the growing momentum behind transparency in health care. Firstly, Quinonez et al consider the increasing expectation of family presence during surgical procedures and resuscitation of loved ones. They entertain the valid merits of family presence, such as the anxiolytic effect it may have as well as increased understanding of procedural goals and enhanced staff professionalism. Conversely, family members may not be psychologically prepared to bear witness to more invasive clinical environments and may serve as a source of distraction to providers. The impact of family presence on medical litigation is unclear. There have been long standing precedents set by way of obstetric and pediatric populations as seen in this infographic. In conjunction with the increased desire for physical presence of loved ones during clinical procedures, so too is there a demand for complete access to all medical records, including even the arcane hieroglyphics of an anesthesia record as detailed by Ramaswamy et al. As federal law now mandates such access, questions naturally arise as to their utility and medicolegal implications. The reader is strongly encouraged to review the concepts elaborated in these articles for in depth appreciation of their considerations.
Η Ελληνική Φορολογική Διοίκηση υπό το πρίσμα της διασφάλισης των δημοσίων εσόδων, της καταπολέμησης της φοροδιαφυγής, της ενίσχυσης της φορολογικής συμμόρφωσης και της αξιοποίησης των νέων πληροφοριακών συστημάτων
Authors: Μαυρίδου Αικατερίνη
Published: September 2022

Η παρούσα Διδακτορική Διατριβή διερευνά ενδελεχώς τον τρόπο οργάνωσης και το πλαίσιο λειτουργίας της Eλληνικής φορολογικής διοίκησης, δίνοντας ιδιαίτερη έμφαση στους τομείς της διασφάλισης των δημοσίων εσόδων, της καταπολέμησης της φοροδιαφυγής, της ενίσχυσης της φορολογικής συμμόρφωσης και της αξιοποίησης των νέων πληροφοριακών συστημάτων. Επιπλέον, αξιολογεί το έως τώρα έργο της φορολογικής διοίκησης εντοπίζοντας προβλήματα, αστοχίες και παραλείψεις, ενώ παράλληλα αναδεικνύονται οι τομείς που παρουσιάζουν θετικά αποτελέσματα. Τέλος, θέτει σαφείς στόχους και προτείνει δράσεις, στις οποίες πρέπει να εστιάσει η φορολογική διοίκηση τα επόμενα χρόνια προκειμένου να βελτιώσει τις διαδικασίες της και να ολοκληρώσει τον μετασχηματισμό της σε έναν σύγχρονο, αποδοτικό και αποτελεσματικό οργανισμό.
Υπερβαρύτητα ανώτερης τάξης στην καμπυλότητα και Κοσμολογία
Authors: Παυλόπουλος Γεώργιος
Published: September 2022

Στην παρούσα διατριβή μελετώνται υπερβαρυτικά πρότυπα ανώτερης τάξης στηνκαμπυλότητα R και τα οποία περιέχουν παραγώγους αυτής. Η μελέτη χρησιμοποιεί την δυϊκήπεριγραφή κατά την οποία η δράση Einstein-Hilbert συζεύγνηται με κατάλληλο πλήθοςβαθμωτών πεδίων.Στο πρώτο μέρος κατασκευάζεται ένα τέτοιο υπερβαρυτικό πρότυπο που στην περιγραφήανώτερης τάξης στην καμπυλότητα R περιέχει όρους R^2, R^3, R\box R. Η κατασκευή γίνεται μετρόπο ώστε στην περιγραφή Einstein να μην εμφανίζονται καταστάσεις φαντασμάτων,φαινόμενο που είναι σύνηθες σε αυτού του τύπου τα υποδείγματα. Επιπλέον εξετάζονται οισυνθήκες ώστε το δυναμικό των βαθμωτών πεδίων να είναι ευσταθές σε ευρεία περιοχή τωνπαραμέτρων.Στο δεύτερο μέρος, ερευνάται η κοσμολογική συμπεριφορά ως προς τον πληθωρισμότέτοιων υποδειγματων. Αρχικά αντιμετωπίζεται υπόδειγμα το οποίο αποτελεί ήπια γενίκευσητου επιτυχούς υποδείγματος Starobinsky. Τέλος, ερευνάται η κοσμολογική συμπεριφορά ωςπρος τον πληθωρισμό του προτύπου ανώτερης τάξης στην καμπυλότητα R και των παραγώγωντης, που κατασκευάστηκε στο πρώτο μέρος. Από την κοσμολογική μελέτη ως προς τονπληθωρισμό των δύο παραπάνω προτύπων, το εύρος των κοσμολογικών παραμέτρων προκύπτεινα είναι της τάξης του προτύπου Starobinsky και υπολογίζονται οι κυρίαρχες διορθώσεις.
Jan Długosz a husytyzm
Authors: Iwańczak Wojciech
Published: September 2022

JAN DŁUGOSZ AND HUSSITISM The subject of the analysis is the role of Bohemia and Hussitism in the works of Jan Długosz. Długosz is one of the many observers and authors who come to similar conclusions, condemning Hussitism and seeing it as a threat to the unity of Christianity. Długosz voices his opinion on account of the debate between the professors of the Kraków Academy and the Hussite theologians in 1431. The article analyzes his views on the possibility of taking the Czech throne by the Polish king as well as the sources of the chronicler’s knowledge about the history of the Czech Republic and its common origin with Poles. The author also recalls Długosz’s participation in diplomatic missions related to Polish-Czech relations. Długosz’s descriptions of clashes with the Hussite troops were analyzed, including the battle of Domažlice. Furthermore, the article shows the religious program of the Hussites, and finally the characteristics of the leaders Jan Žižka and Jan Rokycan made by Długosz.
Dokumenty śląskiej rodziny Hahn (Gallus) w archiwum klasztoru w Herzogenburgu
Authors: Jujeczka Stanisław
Published: September 2022

DOCUMENTS OF THE SILESIAN HAHN (GALLUS ) FAMILY IN THE ARCHIVES OF THE HERZOGENBURG MONASTERY The article concerns documents about the Silesian Hahn (Gallus) family kept in the archives of the monastery of Augustinian Canons in Herzogenburg in Lower Austria. These are documents and files of the monastery in St. Andrä an der Treisen. Among the aforementioned documents concerning the Hahn (Gallus) family, there are 34 originals and a paper notebook from 1595 with notarized copies of 12 documents, some of the texts being duplicated. The article contains detailed records of 35 documents concerning the Hahn family collected in Stiftsarchiv Herzogenburg, Urkunden St. Andrä an der Traisen.
Demystifying Organization Science
Authors: Ahuja Gautam
Published: September 2022

With the journal’s rejection rate of more than 90%, getting published in Organization Science is indeed a salutary achievement. Over the years, however, the volume of submissions in Organization Science has grown significantly, creating a significant reviewing load for the reviewers and diminishing the likelihood of acceptance for authors. To assist submitting authors in better assessing their likelihood of acceptance and to improve it, this paper tries to demystify the journal by identifying what Organization Science looks for in a paper, its key policies and practices, and some key lessons for authors attempting to target this journal.
A Rare Case of Longitudinally Extensive Transverse Myelitis Following Pfizer-BioNTech COVID-19 Vaccination with a Favourable Outcome
Authors: KC Ojbindra , Dahal Punya Hari , Koirala Manisha , Yadav Sumeet Kumar
Published: September 2022

Introduction: mRNA COVID-19 vaccines are very safe, but rare adverse events such as transverse myelitis have been reported after COVID-19 vaccination. Case Description: We report the case of 50-year-old man who presented with progressive lower extremity weakness, back pain and urinary retention after his second dose of the Pfizer COVID-19 vaccine. MRI of the spine revealed longitudinally extensive transverse myelitis (LETM). He recovered completely after treatment with intravenous methylprednisone and physical therapy.  Discussion: This case highlights the rare association between LETM and COVID-19 vaccines and encourages clinicians to maintain a high index of suspicion for prompt diagnosis and treatment.
Ağır Biyotinidaz Eksikliği Olgusunda Yeni Çift Homozigot BTD Gen Mutasyonu
Authors: DEVECİ Kübra , AKAR Halil Tuna , YILDIZ Yılmaz , ÖZGÜL R. Köksal
Published: September 2022

Biyotinidaz eksikliği, nadir görülen otozomal çekinik olarak kalıtılan bir hastalıktır. Erken yenidoğan döneminde tedavi edilmezse ciddi nörolojik kusurlara, metabolik bozukluklara, komaya ve ölüme neden olabilir. Yenidoğanlarda biyotinidaz eksikliği taraması ve biyotin takviyesi ile erken tedavi, semptomların çoğunun ortaya çıkması engellenebilir. Biyotinidaz enzimi, BTD geni tarafından kodlanır. BTD geninde 165'ten fazla mutasyon tanımlanmıştır. Bu olgu bildiriminde Ulusal Yenidoğan Tarama programında tespit edilen, BTD geninde homozigot çift mutasyon saptanan nadir bir tablo sunulmuş olup yeni bir allelik varyant ve genotip bildirilmiştir. Özellikle akraba evliliklerinin sık rastlanıldığı toplumlarda; yaygın görülen mutasyonlar haricinde farklı genetik tabloların da görülebileceği akılda tutulmalıdır.
Çocuklarda Testis Torsiyonu: 10 Yıllık Retrospektif Bir Çalışma
Authors: GÜRSOY Didar , ÇELİKKAYA Mehmet , SEÇİNTİ İlke Evrim , ATICI Ahmet
Published: September 2022

Amaç: Bu çalışmanın amacı çocuk yaş grubunda testis torsiyonlu hastaların klinik, radyolojik ve patolojik özelliklerini, hastaların hastaneye başvuru zamanına göre müdahale yöntemlerini ve testis kurtarma oranlarını belirlemektir.
Gereç ve Yöntemler: Bu retrospektif çalışma Ocak 2011-Haziran 2021 yılları arasında karın ağrısı veya skrotal ağrı ile çocuk cerrahisi kliniğine başvuran ve değerlendirme sonrası testis torsiyonu tanısı alan 0-18 yaş arası hastaları kapsamaktadır. Hastaların yaşı, hastaneye başvuru şikayeti, semptomların süresi, hastaneye başvurduğu ay, etkilenen testisin lateralizasyonu, preoperatif tanı çalışmaları, yapılan müdahalenin tipi (orşiektomi/detorsiyon) ve postoperatif tanı belirlendi. Patoloji birimine inceleme için gönderilen materyallere ait Hematoksilen-Eozin boyalı arşiv preparatları iki patolog tarafından yeniden gözden geçirildi.
Bulgular: Bu 10 yıllık dönemde 0-18 yaş arası 28 hasta testis torsiyonu nedeni ile hastanemize başvurmuştu. Hastaların hepsinde (%100) skrotal ağrı ve hassasiyet mevcuttu. Hastaların 4 tanesi (%14.3) yenidoğandı ve 21 hasta (%75) 12-18 yaşları arasındaydı. Orşiektomi materyallerinin incelenmesinde makroskopik olarak testis parankimi seçilemiyordu ve materyaller hemorajikti. Mikroskopik incelemede hemorajik enfarktüs saptandı.
Sonuç: Akut skrotum çocukluk çağında sık görülen cerrahi acillerdir. Akut skrotuma neden olabilecek çok sayıda antite mevcuttur; ayrıcı tanının doğru ve zamanında yapılması hastayı gereksiz cerrahiden kurtaracak ve testis kaybını önleyecektir.
SNOMED CT: a potential powerhouse in the health record revolution
Authors: Roberts Luke , Lanes Sadie , Cooper Carolyn
Published: September 2022

In this article, Roberts et al discuss the importance of SNOMED CT in improving electronic health records, and the benefits this can bring healthcare organisations, professionals and patients.
The NHS influenza vaccination programme 2022–23: striving for success
Authors: Harris Gemma
Published: September 2022

Health writer Gemma Harris provides an overview of this year's NHS influenza vaccination programme, including key goals and lessons learnt from the COVID-19 vaccine rollout.
Why do we need to invest in fetal cardiac nurse specialists? The Brompton model explained
Authors: Tooth Sophie , Doughty Victoria , Lumanisakio Teresa , De Sousa Susana
Published: September 2022

Tooth et al outline the model of fetal cardiac care implemented at the Royal Brompton Hospital and the crucial role of the fetal cardiac nurse specialist.
Temporomandibular disorders. Part 5: surgical management
Authors: Crawford Charles , Foster-Thomas Emma , Oluwajana Funmi , Clarke Peter , James Martin , Khandavilli Sunil , Kalantzis Athanasios
Published: September 2022

The temporomandibular joint (TMJ) is a complex arrangement with high functional requirements. Surgery is therefore only considered when conservative management has not been successful. Surgery may not always benefit and carries the risk of the condition worsening. There is a range of techniques available to the surgeon. The most commonly used is arthrocentesis and this is also the least invasive. The end-stage option for patients is total joint replacement. Whichever surgery the patient has received, it is likely that they will be in need of careful management by the primary care team for their continuing care. This article, the fifth in a series of six, outlines the scope of TMJ surgery.

CPD/Clinical Relevance: A range of techniques is available for TMJ surgery, and many post-surgery patients will require routine dental management in the primary care setting.
Pregnancy and dentistry: a guide for the general dental practitioner. Part 2
Authors: Curtin Claire , Stokes Simon , Shah Fayjel
Published: September 2022

Pregnancy is a unique time in a woman's life with many physiological, physical, emotional and hormonal changes occurring. It can also be quite an anxious time for women particularly in the first trimester when the risk of miscarriage is at its highest. Uncertainty still exists around the topic of dental treatment and care during pregnancy, which may create challenges for both the patient and the dental team.

CPD/Clinical Relevance: The treatment options available when managing pregnant patients and for safe prescribing for this population are described.
The dental effects of head and neck rhabdomyosarcoma treatment: a case series
Authors: Truman Angharad , Forbes-Haley Claire
Published: September 2022

Rhabdomyosarcoma (RMS) is a malignant soft tissue neoplasm of skeletal muscle origin. Approximately 40% of cases of RMS are sited in the head and neck region and nearly 65% of cases are diagnosed in children less than six years of age. Treatment for RMS involves a multimodality approach including surgery, chemotherapy and radiotherapy. When children are exposed to such treatments there are often associated long-term adverse effect which may affect the patients' dento-alveolar growth and development. Three cases are described highlighting these adverse effects and the treatments used for oral rehabilitation.

CPD/Clinical Relevance: To inform readers of the long-term effects of rhabdomyosarcoma treatment on the dento-alveolar development.
Managing compromised first permanent molars in children: minimally invasive treatment protocols for practitioners
Authors: AlKhalaf Reem , Rosa Thamirys Costa , Vieira Fernanda Gabriela de Fatima , Neves Aline de Almeida , Hosey Marie Therese , Banerjee Avijit
Published: September 2022

Employing minimally invasive operative techniques to manage compromised first permanent molars is discussed as a treatment regimen to achieve a favourable medium-to long-term prognosis in modern paediatric dental management. It is known that patient cooperation, stage of dental development and eruption state, as well as chronological age and severity of tissue breakdown of the compromised tooth have an influence on the prognosis of treatment.

CPD/Clinical Relevance: Understanding the various prognostic factors involving compromised first permanent molar teeth is essential if optimum treatment is to be provided.
Resin-retained bridges: considerations to maximize enamel bonding and aesthetics for abutment teeth with compromised contour
Authors: Hudson Joshua , Denhard Krupti
Published: September 2022

The provision of resin-retained bridges (RRBs) on abutment teeth that require composite resin build-ups often proves challenging. This article presents a technique, represented through two clinical cases, that aims to reduce some of the issues associated with such scenarios. It describes the simultaneous cementation of the RRB while also undertaking composite resin additions. It showcases the advantages of such a technique – particularly in terms of maximizing enamel surface area available for bonding to the retainer, and thereby potentially improving the longevity of the prosthesis.

CPD/Clinical Relevance: Careful design and execution is required when providing resin-retained bridgework.
Background and complications of dermal fillers: the increasing use of non-surgical facial aesthetics in dental practice
Authors: Ahmed Tanya , McCarthy SJ , Cartner A , Pilkington RJJ , McCormick RS
Published: September 2022

There has been a noticeable increase in the number of patients who present to oral and maxillofacial surgery (OMFS) departments for treatment of post-operative complications of dermal fillers and botulinum toxin. These complications are more likely when the treatments are performed by untrained persons or self-administered by patients. Occasionally, these adverse outcomes cannot be avoided, even when products are administered by medically trained professionals. This review includes two cases and discusses some of the key issues surrounding these products so that patients can be informed of the benefits and risks with these types of non-surgical aesthetic procedures and, where possible, reduce the risk of complications occurring.

CPD/Clinical Relevance: Appropriate knowledge of facial anatomy and different types of dermal fillers is necessary to reduce the risk of complications associated with injection of these products.
Flangeless horseshoe maxillary complete denture: a prosthodontic solution to maxillary tori
Authors: Pai Sandeep , Leyssen Wouter
Published: September 2022

Tori may present difficulties in achieving a retentive prosthesis with full palatal coverage. Management of tori in such cases may involve attempting to avoid coverage of the torus, providing relief over the torus, or surgical reduction/removal. This article presents a case where a patient who presented with a large maxillary torus was managed with a non-surgical approach, which enabled provision of a successful prosthesis. Dental practitioners could consider this approach for selected cases.

CPD/Clinical Relevance: Thorough prior planning and a modified denture design can be used to provide an effective clinical solution for maxillary and mandibular tori.
CAPACIDADES POLÍTICO-RELACIONAIS ESTABELECIDAS PELA COMUNICAÇÃO DIGITAL: proposição de um instrumento de análise
Authors: Silva Lucas Braga da , Meneses Veronica Dantas , Almeida Lia de Azevedo
Published: September 2022

Considerando que o meio digital tem sido cada vez mais utilizado nas atividades governamentais, pode-se dizer que, a comunicação assume papel de destaque no desenvolvimento de capacidades político-relacionais neste contexto, e assim pode fortalecer ainda mais as ligações entre governo e sociedade. No entanto, ainda é um tema pouco explorado na literatura de administração pública e também nos estudos de comunicação, para isto, este trabalho busca unir as duas linhas de pesquisa, propondo um instrumento que viabilize identificar e analisar como as capacidades político-relacionais ocorrem por meio da comunicação governamental.
MANHÃS DE SETEMBRO E PERTENCIMENTO FAMILIAR: imagens de (in)cômodos domésticos
Authors: Fischer Sandra , Vaz Aline
Published: September 2022

O estudo propõe um olhar analítico à ficção seriada Manhãs de setembro (Luis Pinheiro e Dainara Toffoli; 2021, Amazon Prime Video), cuja protagonista é uma travesti que inesperadamente se depara com a presença de um filho em sua vida. Enquanto ele se acomoda ao ambiente da casa da mãe, ela incomoda-se. Ao colocar em tela imagens dos contrários e contraditórios que se estabelecem na tessitura das relações familiares, os arranjos estéticos da série operam como construtores de brechas e promotores de encontros sensíveis.
Evidence of diet supplementation with vitamin C protecting honeybees from Imidacloprid induced peroxidative damage: a study with Apis cerana indica
Authors: Syama P. S.  , Kumar C. V. Sreeranjit
Published: September 2022

Neonicotinoids are one of the major stresses contributing to the decline in the population of honeybees. Worker bees are prone to various stress factors during foraging and are susceptible to Imidacloprid due to the reduction in the number of genes encoding for the major enzyme families responsible for the detoxification of toxins. The present study worked on the hypothesis that the dietary supplementation of Ascorbic acid (VIT C) could reduce the peroxidative damage in the worker bees of Apis cerana indica exposed to sub-lethal concentration of imidacloprid (IMD). Furthermore, we also evaluated the role and efficacy of VIT C supplementation on the cytoarchitecture of midgut tissues on exposure to IMD. Colonies of honeybees were maintained by providing sugar syrup to the control group and sugar syrup supplemented with 0.2% VIT C for the experimental group for six months. Worker bees from both groups were randomly collected and exposed to 0.001 mg/mL IMD. To study the peroxidative damage, the activities of various enzymes were analyzed. The activities of antioxidant enzymes including Catalase, Superoxide Dismutase, Glutathione S Transferase, and Glutathione Peroxidase in the hemolymph and midgut tissues of worker bees were significantly decreased due to exposure to IMD as a single agent. However, their activities showed a significant elevation under diet supplementation with VIT C. Histological examination revealed midgut tissue damage and the rupture of peritrophic membrane among the workers exposed to IMD as compared with the control group. The damage to the midgut was alleviated and the peritrophic membrane was found to be intact in the worker bees supplemented with VIT C. Our results indicated that the dietary supplementation of VIT C has the potential to maintain the redox status and thereby can offer protective potential against the peroxidative damages induced by the sub-lethal concentration of IMD.
Divergence of Ant Communities Over Time in a Fragmented Atlantic Rain Forest Landscape
Authors: Soares Ribeiro Vanessa Soares Ribeiro , Navarro Paolucci Lucas , Schoereder José Henrique , Ribeiro de Castro Solar Ricardo
Published: September 2022

Habitat fragmentation changes biological communities and its spatiotemporal dynamics – which may lead to either biotic homogenization or heterogenization along time and space. Both processes can occur by addition, replacement or loss of species within communities, altering compositional similarity across the landscape. We investigated which of these two processes (biotic homogenization or heterogenization) occurs, and its possible underlying mechanism, over 15 years in an Atlantic Forest landscape using ants as model organisms. We sampled ants in 17 forest fragments across three different years, compared their composition similarity, species richness, and species richness of groups classified according to their habitat preferences. We sampled a total of 132 ant species. Ant communities in fragments diverged over time, suggesting they experienced an idiosyncratic structuring process. This biotic heterogenization occurred through an additive process, as ant species richness increased over time, mainly due to an increase of generalist ant species, and a decrease of forest specialist ant species. These changes occurred despite the higher forest cover in the landscape along years. Since different species can perform different functions in ecosystems, this biotic heterogenization may have implications for ecosystem functioning. Investigating how disturbances structure biological communities over time, especially those performing important ecosystem functions, can shed light to our understanding of possible changes in ecosystem functions and consequently for forest regeneration.
The State of the Art of the Tunisian Apidae Fauna (Hymenoptera: Anthophila)
Authors: Ben Khedher Hassib , Braham Mohamed , Chaieb Ikbal
Published: September 2022

Based on a review of the available literature, the state of the art and a checklist of the fauna of the Apidae family of Tunisia is presented. The first list of the species of the family is given. 184 species and subspecies belonging to 19 genera, 12 tribes and three subfamilies were listed. Distribution of recorded taxa from Tunisia and from the world is provided. Apinae is the subfamily with the highest species richness with 89 species. Nomada has the highest number of species represented by 62 taxa. The Tunisian East center is the least species-diversified regions with only 16 species and subspecies reported so far. Five species are endemic to Tunisian fauna. Eight Nomada and one Anthophora species were collected from Tunisia, but their identity should be re-confirmed. The presence of Thyreomelecta sibirica (Radoszkowski, 1893) in Tunisia is doubtful and a re-examination and confirmation are needed.
Ant species that remove diaspores alone are more efficient removers
Authors: Wilker Icaro , Rabelo Mariana A. , Angotti Marina A. , Ribas Carla R.
Published: September 2022

Secondary diaspore removal on the ground is an important ecosystem process. In this process, solitary foraging ants with larger body sizes are more efficient because they may remove more diaspores, faster and carry them at greater distances. Therefore, we sought to test the effects of the sizes of the morphological traits of ants, removal strategy, and nest distance on secondary diaspore removal, testing hypotheses related to the efficiency of this process. We evaluated the removal of artificial diaspores by ants in 15 areas of Cerrado sensu stricto (tropical savanna), collecting data on diaspore removal strategy (solitary or group), nest distance, diaspore discovery time, diaspore removal time, and the number of diaspores removed. Larger ants tended to remove diaspores alone and remove diaspores faster than smaller ones. Ants that removed diaspores alone removed more diaspores than ants that removed diaspores in groups. However, we did not find a linear relationship between ant size and diaspore removal. This is likely due to a limitation on, or a preference by larger ants for removing larger diaspores, while the smaller diaspores may have hindered manipulation or been less attractive to larger ants. Thus, the removal strategy was the best predictor of efficient diaspore removal performance, where the solitary foraging ants discover and remove diaspores quickly and remove more diaspores, mainly from the closest nests to the sampling point. However, the benefits (or not) of removing more diaspores still need to be evaluated.
Single-shot 3D shape acquisition using a learning-based structured-light technique
Authors: Nguyen Andrew-Hieu , Ly Khanh L. , Qiong Li Charlotte , Wang Zhaoyang
Published: September 2022

Learning three-dimensional (3D) shape representation of an object from a single-shot image has been a prevailing topic in computer vision and deep learning over the past few years. Despite extensive adoption in dynamic applications, the measurement accuracy of the 3D shape acquisition from a single-shot image is still unsatisfactory due to a wide range of challenges. We present an accurate 3D shape acquisition method from a single-shot two-dimensional (2D) image using the integration of a structured-light technique and a deep learning approach. Instead of a direct 2D-to-3D transformation, a pattern-to-pattern network is trained to convert a single-color structured-light image to multiple dual-frequency phase-shifted fringe patterns for succeeding 3D shape reconstructions. Fringe projection profilometry, a prominent structured-light technique, is employed to produce high-quality ground-truth labels for training the network and to accomplish the 3D shape reconstruction after predicting the fringe patterns. A series of experiments has been conducted to demonstrate the practicality and potential of the proposed technique for scientific research and industrial applications.
Exploring optimal granularity for extractive summarization of unstructured health records: Analysis of the largest multi-institutional archive of health records in Japan
Authors: Ando Kenichiro , Okumura Takashi , Komachi Mamoru , Horiguchi Hiromasa , Matsumoto Yuji
Published: September 2022

Automated summarization of clinical texts can reduce the burden of medical professionals. “Discharge summaries” are one promising application of the summarization, because they can be generated from daily inpatient records. Our preliminary experiment suggests that 20–31% of the descriptions in discharge summaries overlap with the content of the inpatient records. However, it remains unclear how the summaries should be generated from the unstructured source. To decompose the physician’s summarization process, this study aimed to identify the optimal granularity in summarization. We first defined three types of summarization units with different granularities to compare the performance of the discharge summary generation: whole sentences, clinical segments, and clauses. We defined clinical segments in this study, aiming to express the smallest medically meaningful concepts. To obtain the clinical segments, it was necessary to automatically split the texts in the first stage of the pipeline. Accordingly, we compared rule-based methods and a machine learning method, and the latter outperformed the formers with an F1 score of 0.846 in the splitting task. Next, we experimentally measured the accuracy of extractive summarization using the three types of units, based on the ROUGE-1 metric, on a multi-institutional national archive of health records in Japan. The measured accuracies of extractive summarization using whole sentences, clinical segments, and clauses were 31.91, 36.15, and 25.18, respectively. We found that the clinical segments yielded higher accuracy than sentences and clauses. This result indicates that summarization of inpatient records demands finer granularity than sentence-oriented processing. Although we used only Japanese health records, it can be interpreted as follows: physicians extract “concepts of medical significance” from patient records and recombine them in new contexts when summarizing chronological clinical records, rather than simply copying and pasting topic sentences. This observation suggests that a discharge summary is created by higher-order information processing over concepts on sub-sentence level, which may guide future research in this field.
Causes of neonatal mortality using verbal autopsies in rural Southern Nepal, 2010–2017
Authors: Saya Ayesha R. , Katz Joanne , Khatry Subarna K. , Tielsch James M. , LeClerq Steven C. , Mullany Luke C.
Published: September 2022

The burden of neonatal mortality remains high worldwide, particularly in South Asia. Verbal Autopsy is a method used to identify cause of death (COD) where vital registration capabilities are lacking. This study examines the causes of neonatal mortality in a large study population in rural Southern Nepal. The data used is from a larger cluster-randomized community-based trial. The study includes 984 neonatal deaths with complete verbal autopsy information which occurred between 2010 and 2017. The InterVA-5 software was used to identify COD. COD included severe infection (sepsis, pneumonia, meningitis/encephalitis), intrapartum related events (identified as birth asphyxia), congenital malformations, and other. The neonatal mortality rate was 31.2 neonatal deaths per 1000 live births. The causes of neonatal mortality were identified as prematurity (40%), intrapartum related events (35%), severe infection (19%), congenital abnormalities (4%), and other (2%). A high proportion, 42.5% of neonatal deaths occurred in the first 24 hours after birth. Over half (56.4%) of deaths occurred at home. This large prospective study identifies population level neonatal causes of death in rural Southern Nepal, which can contribute to national and regional COD estimates. Interventions to decrease neonatal mortality should focus on preventative measures and ensuring the delivery of high risk infants at a healthcare facility in the presence of a skilled birth attendant.
Effect of decompression and online transmission on the dimensional changes of .stl files generated by intra-oral scanning
Authors: Bueno Juliano Martins , Gouveia Carolina Guarniéri , Mundim Mayara Barbosa Viandelli , Franco Ademir , Junqueira José Luiz Cintra , Nascimento Monikelly do Carmo Chagas
Published: September 2022

Intraoral scans became part of the virtual planning in Dentistry. In the new scenario of digital workflows, dental clinics and laboratories had to establish an online communication that requires the compression, decompression, and transmission of 3D files. Knowledge about the effects of these procedures on the dimensional properties of the files is fundamental to ensure a more realistic virtual planning. The aim of this study was to assess the influence of 3D file compression, decompression, and online transmission on the dimensional properties of dental models from intraoral scanning. Intraoral scan files in.stl format of 50 patients were selected from the database of a dental radiology clinic, with 25 of these patients with mixed dentition and 25 with permanent dentition. The maxilla and mandible scans of each patient were included in the study, generating a total of 100 files. A folder with the 100 files was created and replicated six times with different labels (A, B, C, D, E, F), totaling a sample number of 600 files. Folder A was compressed by WinZip and then decompressed. Folder B went through the same process, but the step of compression and decompression by WinZip was repeated 10 times. The folders C, D, E, F were sent, respectively, through the platforms WeTransfer, Dropbox, Google Drive, and OneDrive, then each of them was downloaded in their respective platforms. After the six folders went through the compression process and were sent by the platforms, each file in the folder was compared with its original file by superimposing the 3D images and identifying the dimensional deviation in the compressed file in relation to the original file. We observed that there were no differences between the six groups regarding dimensional changes from the compression, decompression and online transmission processes. The lack of dimensional changes was observed for the sets of permanent and deciduous. teeth We concluded that it is possible to compress, decompress, and transfer.stl format files online without causing dimensional distortions in the 3D model.
Exploring the feasibility of a network of organizations for pain rehabilitation: What are the lessons learned?
Authors: Lamper Cynthia , Huijnen Ivan P. J. , Kroese Mariëlle E. A. L. , Köke Albère J. , Brouwer Gijs , Ruwaard Dirk , Verbunt Jeanine A. M. C. F.
Published: September 2022

Background and aims

Integration of care is lacking for chronic musculoskeletal pain patients. Network Pain Rehabilitation Limburg, a transmural health care network, has been designed to provide integrated rehabilitation care from a biopsychosocial perspective to improve patients’ levels of functioning. This feasibility study aims to provide insight into barriers and facilitators for the development, implementation, and transferability.

Methods

This study was conducted with a three-phase iterative and incremental design from October 2017 to October 2018. The network comprises two rehabilitation practices, and three local primary care networks, with a general practitioner together with, a mental health practice nurse, and a physiotherapist or exercise therapist. These stakeholders with a random sample of participating patients took part in evaluations, consisting of interviews, focus groups, and observations. Field notes and observations were recorded during meetings. The Consolidated Framework for Implementation Research guided data collection and analysis. Results were used to refine the next phase.

Results

According to health care professionals, guidelines and treatment protocols facilitate consistency and transparency in collaboration, biopsychosocial language, and treatment. One mentioned barrier is the stigmatization of chronic pain by the general population. In regular care, approaches are often more biomedical than biopsychosocial, causing patients to resist participating. The current organization of health care acts as a barrier, complicating implementation between and within practices. Health care professionals were enthusiastic about the iterative, bottom-up development. A critical mass of participating organizations is needed for proper implementation.

Conclusion

Network Pain Rehabilitation Limburg is feasible in daily practice if barriers are overcome and facilitators of development, implementation, and transferability are promoted. These findings will be used to refine Network Pain Rehabilitation Limburg. A large-scale process and effect evaluation will be performed. Our implementation strategies and results may assist other health care organizations aspiring to implement a transmural network using a similar model.

Trail registration

Registration number: NTR6654 or https://trialsearch.who.int/Trial2.aspx?TrialID=NTR6654.
Eigenvalue productivity: Measurement of individual contributions in teams
Authors: Müller Julia , Upmann Thorsten
Published: September 2022

While the output of a team is evident, the productivity of each team member is typically not readily identifiable. In this paper we consider the problem of measuring the productivity of team members. We propose a new concept of coworker productivity, which we refer to as eigenvalue productivity (EVP). We demonstrate the existence and uniqueness of our concept and show that it possesses several desirable properties. Also, we suggest a procedure for specifying the required productivity matrix of a team, and illustrate the operational practicability of EVP by means of three examples representing different types of available data.