bluuebunny/crossref_metadata_2025 huggingface dataset:
University Students' Perceptions of Ethical Leadership and Work Ethics
Authors: PIRICZ Noemi
Published: October 2023

To achieve the sustainable development goals, it is recommended that organizations worldwide set and adhere to ethical and governance standards. Workplace ethics is an expression of the values an organization holds towards its employees, and therefore includes the behavior of managers and their leadership style and practices. The young generations' perceptions of ethical leadership are worth exploring because they will be the decision-makers of the future. In our research, we interviewed Hungarian university students - mainly studying economics - about ethical leadership and work ethics who have had work experience (N=143). We developed our hypotheses based on Starratt's three-dimensional ethical model and conducted SEM analysis using SmartPLS4 software. We found that the Ethics of Justice factor influences the Ethics of Critique and Ethics of Care factors. Our results also show that achieving greater social justice is important to them in their decision-making. The surveyed Generation Z in Hungary considers the interests of both the individual and the community to be important for workplace ethics. Our research contributes to young people's understanding of ethics in the workplace and ethical leadership.
Qasidas of ‘Amr b. Sâlim al-Khuzâ ‘î and Ḥassan b. Thâbit on the Eve of the Conquest of Mecca
Authors: KOKSOY Mesut
Published: October 2023

Arabs have expressed their joys, sorrows, praises and satires more effectively with poetry throughout history. Thus, the poets of the tribes were seen as the most respected people after the chief of the tribe. ‘Amr b. Sâlim al-Khuzâ‘î is one of the poets of the Khuzâ‘a tribe. In the Hudaybiya peace treaty between Muslims and Qurayshi infidels, the Khuzâ'a tribe took place as an ally of the Muslims, while the Banu Bakr tribe took place as an ally of the Qurayshi infidels. Some people from the Banu Bakr tribe, with the help of the notables of the Qurayshi tribe, violating the peace treaty killed 23 people in their raid on the Khuzâ‘a tribe. ‘Amr b. Sâlim al-Khuzâ'î, having come to Medina with 40 people from his tribe, recited his 8 couplet qasida in the presence of the Prophet to complain about the pain they experienced and to respond to the attack. On this event, the Prophet started an expedition against the Qurayshis who broke the agreement, which would result in the conquest of Mecca. During this preparations of the expedition, one of the prophet’s poets, Ḥassan b. Thabit also wrote an 6 couplet qasida in which he denounced the attack on the Khuza‘a tribe and encouraged the Muslims to prepare for the expedition. These poems which arouse deep emotions, to convey messages of encouragement and threat, to buid a collective consciousnes and to act as a trigger to change the course of history highlight the impact and its indispensable role of poetry as an instrument of communication and war during the era of Sadr al-Islam. In this study these two qasidas which which has an important place in the history of Islam, are analyzed.
Ketekunan Iman Di Dalam Penantian Kristus Berdasarkan Ibrani 10:37-38
Authors: Linus Syah Putra Gulo  , Yeremia Hia
Published: October 2023

Di dalam Perjanjian Baru, kitab Ibrani adalah salah-satu kitab yang banyak mengutip teks Perjanjian Lama dan menyinggung tentang iman. Bahkan kitab ini sendiri yang mendefenisikan iman. Para penulis Perjanjian Baru lebih cenderung menggunakan versi Ibrani teks masoretik teks, dengan berbaga metode penafsiran tradisi Yahudi kuno. Metode penafsiran, misalnya: historis, preteris, furutis, idealis. Penulisan artikel ini dilakukan dengan metode kualitaif yang, bentukanya eksegeis. Eksegesis adalah metode untuk menemukan dan memahami pesan dari sang penulis. untuk memahami penggunaan Perjanjian Lama di alam Perjanjian Baru, khususnya tentang teks-teks yang berbicara tentang Eskatologi atau kedatangan Tuhan yang kedua kali. Dari berbagi persepektif masih banyak yag harus digali, mulai daris sisi soteriologinya dan eskatologinya. Tujuan penulisan artikel ini, untuk menjelaskan makna penggunaan kutipan Perjanjian Lama di dalam Perjanjian Baru oleh si penulis dan kaitan-nya dengan iman yang tekun dalam menantikan kedatangan Kristus yang kedua kali. Penulis menggambarkan penggunaaan Perjanjian Lama oleh penulis di dalam ayat 10:37-38, kemudian, Penulis akan menguraikan korelasinya dengan iman yang tekun terhadap orang Kristen masa kini dalam hal menantikan kedatangan Kristus yag kedua kalinya.
Word Formation Process in Adele’s “30” Song Album: A Comprehensive Morphological Analysis
Authors: Fitria Aprilia  , Neisya  , Fitri Sonia
Published: October 2023

This research aims to analyze comprehensively morphological process of word formation in song album “30” by Adele. Word formation focuses on the process of making or constructing new words based on other words or morphemes. Descriptive qualitative method was applied since the data were in the form of words, phrases, and sentences. The theory proposed by Yule (2017) was used in analyzing the word formation process. The data of this research were 12 songs contained in song album “30” by Adele. Based on the analysis, it was found that there were 6 types out of 14 types of word formation process in song album “30” by Adele. Specifically, this research found 44 data of word formation process. There were 6 data of compounding, 1 data of clipping, 1 data of backformation, 1 data of acronyms, 2 data of derivation and 33 data of prefixes and suffixes.  Prefixes and suffixes were concluded as the most dominant type of word formation process that was found in song album “30” by Adele.
Agentive Movement Verbs in the Study of the Angkola Batak Language
Authors: Zainuddin Saragih  , Mulyadi
Published: October 2023

The Angkola Batak language is a regional language that has 2 types of verbs, namely agentive motion verbs and patient motion verbs. In this study we will discuss agentive motion verbs.The purpose of this study is to determine the categorization of agentive verbs in the Batak Angkola language so that there are no mistakes in the meaning of words. This study used a qualitative approach with data collection techniques using interviews.The results of this study indicate that agentive movement verbs (VGA) are categorized based on eleven components.
Semantic Structure Verb ‘open’ in Indonesian and Japanese : Natural Semantic Metalanguage
Authors: Jaka Budiman  , Mulyadi  , Siti Muharami Malayu
Published: October 2023

This study discusses the semantic structure of the verb 'open' in Indonesian and Japanese. This research uses the MSA theory pioneered by Wierzbicka. Data was obtained and collected using the interview method. The results of the findings obtained two categorizations of the verb 'open' in Indonesian and Japanese, they are: a) using tools (by using tools) and b) using hands (by part of body). The semantic structure of the verb 'open' in Indonesian and Japanese is almost similar. Even so, there are several different verbs in the semantic structure, including: meretas (開封するkaifū suru), merintis & merambah (開拓する kaitaku suru), mementang, membentangkan, membeber, menggelar & menghamparkan (広げるhirogeru), dan menyingkap (捲るmekuru & はだけるhadakeru). The difference in the semantic structure of the Indonesian and the Japanese language occurs due to the cultural characteristics of the two peoples and the different language differences. Thus, it also results in a different mindset in each language.
The Analysis of Form, Functions and Code Switching Factors in the Film Kehormatan di Balik Kerudung
Authors: Ifa Lathifah  , Agus Sariono  , Ali Badruddin
Published: October 2023

Code-switching is the alteration or shift in the usage of one language to another within the context of communication, often occurring spontaneously and naturally. This study aims to find code switching forms, its underlying  factors, as well as  its function found in the Kehormatan di Balik Kerudung. The data of this research are players’ utterances in which code switching appear. The data collected were analyzed using Poplack’s theory (1980) to determine the form of code switching, Grosjean’s theory (2010) to find the functions of code switching, and Azhar’s, et al (2011) to find the factors behind the code switching. The results of this study indicate that extrasentential code-switching in the form of Javanese particles highly dominates the code-switching practices compared to the other two, namely intrasentential and intersentential, namely there were 30 extrasentential code-switching, 22 intrasentential and 7 intersentential. Some of the code-switching functions, are among others: to start a conversation, to confirm the conversation, to end the conversation, to confirm or emphasize statements, to ask for approval, and to answer doubts. Six factors underlying the code switching were among others: speakers, speech partners, topics of conversation, place and time of speech events, functions and objectives, as well as variety and level of speech.
The estimated environmental impact on the distribution, mass and abundance of plastics in aquatic ecosystems
Authors: Erzinger Gilmar Sidnei , Erzinger Gabriel , Häder Donat Peter
Published: October 2023

Plastic began to be manufactured on a commercial scale in the 1950s, and people saw its attractive properties as revolutionary. Plastic has proven to be a very attractive product because it is lightweight, water resistant, heat and electric insulating and extremely durable. It is also very cheap to make. The starting ingredient is the less commonly killed organic raw material of petroleum, natural gas, or plant material - an increasingly attractive option as the rage for fossil fuels grows. Consequently, plastic can remain for hundreds of years up to 400 years for its degradability in the environment (unless recycled or incinerated). More than a third of plastic is manufactured for single use, most of which is disposed of in the environment within one year of manufacture. In particular, about 8 million tons enter the oceans each year. The durable nature of plastic is remarkable because even though it is made of organic matter, living things cannot digest and break it - a stark contrast to the waste of food and paper. Plastic debris can be distinguished into macroplastics and microplastics. Furthermore, exposure to heat an solar UV radiation makes the fragments brittle so that they easily crumble producing secondary microplastics forming persistent organic pollutants. In addition, there is a sizable fraction of primary microplastics, e.g. microbeads. These pollutants are found in terrestrial and marine aquatic ecosystems and are considered a serious problem of high environmental impact.
Numerical analysis of the thermal behaviour and performance of a brake system with temperature-dependent material properties
Authors: Hassan M.A. , Ali M. , Abdullah O.I.
Published: October 2023

The brake system is the most significant component of a vehicle because it protects the driver, passengers, other road users, and property on both sides of the road. The basic principle of the disc brake system depends on the friction-based between the brake pads and rotor disc.The paper introduced a developed 3D finite element thermal model of the brake system to simulate the heat generated by friction in the vehicle's disc brake.The results presented the surface temperature at any instant of the disc brake under various initial velocities when the materials properties of the rotor disc and pad depend on temperature.The main aim of the present paper is to build a numerical model to simulate the braking process under various initial vehicle velocities and investigate the influence of the material properties when they function on temperature and constant.The maximum difference between the two cases (contact and depend on the temperature) was 17 K for the initial velocity of 144,120. Also, it was found out that the percentage differences of the surface temperature increasing with the rise in initial vehicle velocity were 323% and 392.5% when the initial velocity of the vehicle increased from 100 km/h to 144 km/h.
CANNABIS THIN LAYER CHROMATOGRAPHY (TLC) CHEMO TYPING: HOW ACCURATE IS TLC COMPARED TO HIGH PRESSURE LIQUID CHROMATOGRAPHY?
Authors: Fortes Paulo Jordão de Oliveira Cerqueira , Alencar Nelson Leal , Nunes Livio Cesar Cunha , De Almeida Erik Amazonas , Dos Santos Mirian Lima , Deeter Thomas , Tinman Salomon
Published: October 2023

Problem: Brazilian Cannabis Associations (BCA) search for methods of reducing their costs and increasing their quality control of Cannabis spp. Oil and extracts. The significant difficulties presented by ABRACAM (Associação Brasileira Cannabis Medicinal) to UFPI professors were to standardize cannabinoids profiles of its plants and guarantee the same levels of cannabinoids on its artisanal extracts. ABRACAM has difficulty standardizing plant cannabinoids profiles due to Cannabis spp. Phenotypic plasticity, or the ability of Cannabis spp. to change attributes like the size of leaves, levels of secondary metabolites, stems structures, flowering period, among others. The second problem is that artisanal extract combines different production batches of non-tested extractions. It is necessary to quantify and qualify each cannabinoid and how much is on artisanal Cannabis production. Aiming to solve the ABRACAM production problem, UFPI and CANNAPI suggested manual testing practices to test cannabis and its derivates. This article results from validation tests performed at ABRACAM to determine how precise manual methods are to quantify cannabinoids.  Methods: This research compared the cannabinoids results of an off-the-shelf Thin Layer Chromatography (TLC) cannabinoids profile test kit with the results of a High-Pressure Liquid Chromatography (HPLC). UFPI perfect the method from the vendor manual after running sixty quantifications from one sample.  Results: The TLC error compared to HPLC was between approximately 0,5% and 1%. ABRACAM differentiated the Chemotype Profile of its High THC varieties and High CBD varieties. For High CBD variety, the outdoor cultivation proportionated greater cannabinoids levels. Conclusions: The comparison pointed that TLC may be used as testing equipment for this Brazilian Association due to its artisanal production license. This article concludes that precision is the key to medication production, and the TLC error may be accepted for artisanal production but not as a standard for precision. For scientific purposes, TLC is a strong hypothesis builder, and for agriculture, purposes may be a vital tool point the right time to harvest.
PENGARUH HARGA DAN PROMOSI TERHADAP KEPUTUSAN PEMBELIAN TAS KANAYA N FRIENDS MELALUI APLIKASI TOKOPEDIA
Authors: Putra Erick Julian Prima , Wijayanti Ani , Safria Dhuha
Published: October 2023

Penelitian ini memiliki tujuan untuk menjelaskan pengaruh secara parsial dan simultan antara variabel harga dan promosi terhadap keputusan pembelian tas Kanaya N Friends melalui aplikasi tokopedia. Jenis penelitian ini menggunakan penelitian kuantitatif karena mengarah kepada metode pengukuran dan sampel untuk menguji variabel dan hipotesis. Dengan menggunakan program SPSS versi 27, peneliti melakukan beberapa pengujian antara lain uji validitas, uji reliabilitas, uji normalitas, uji multikolinearitas, uji heteroskedastisitas, uji t, uji F, analisis regresi linear berganda dan uji koefisien determinasi. Populasi dalam penelitian ini berjumlah adalah seluruh pembeli tas Kanaya N Friends melalui aplikasi toopedia, dan sampel pada penelitian ini berjumlah 50. Hasil penelitian ini diperoleh bahwa harga berpengaruh secara parsial dan signifikan terhadap keputusan pembelian tas Kanaya N Friends melalui aplikasi tokopedia. promosi berpengaruh secara parsial dan signifikan terhadap keputusan pembelian tas Kanaya N Friends melalui aplikasi tokopedia. harga dan promosi secara simultan berpengaruh positif terhadap kinerja karyawan.
ISSB Agenda Consultation
Authors: Peters Sandra
Published: October 2023

CFA Institute responds to ISSB’s Request for Information: Consultation on Agenda Priorities.
Análise do desempenho produtivo de cultivares de bananeiras em áreas de ocorrência de Sigatoka amarela para a região Norte de Minas Gerais
Authors: Silva Tatiane Carla , Pacheco Dilermando Dourado
Published: October 2023

Este livro aborda profundamente a cultura da banana na região Norte de Minas Gerais, especificamente focando na problemática da doença Sigatoka amarela que afeta a produtividade das plantações locais. Atualmente, a variedade "Prata Anã" é a mais popular na região, mas infelizmente, é suscetível a essa doença. A obra começa apresentando o cenário atual da produção de banana em Minas Gerais e introduz a iniciativa da Empresa Brasileira de Pesquisa Agropecuária (EMBRAPA), em colaboração com outras instituições, para introduzir e desenvolver variedades resistentes a essa enfermidade. É feita uma análise detalhada de diversas cultivares, avaliando a adaptabilidade, produtividade e resistência à sigatoka amarela.
Plastics in the environment and trends for the future
Authors: Silva Welleson Roberto de Lira , Lima Júlia Guedes de , Campos-Takaki Galba Maria
Published: October 2023

The studies carried out are about the first molecules, classification, properties and environmental problems caused by the rampant disposal of plastics. In this context, with the increase in the unbridled consumption of plastic, which has been contributing to major contamination in all environments, mostly culminating in the oceans. It should be noted that polypropylene is one of the most used polymers in the manufacture of flexible plastic packaging and the accumulation of these materials in the environment, especially in the oceans, has been causing several negative impacts on the planet's biodiversity. An alternative to the problems caused by the improper disposal of this waste would be the replacement of traditional plastics with biodegradable and compostable polymers from renewable sources whose life cycle tends to be less polluting, since, under favorable conditions, they degrade in biologically active environments, not producing toxic waste for the environment. Therefore, it becomes necessary to implement legislations that favor the use of bioplastics over conventional plastics and the changes in consumer behavior that drive the market for biopolymers. The problems of plastics in the environment and in human health are presented as a function of the understanding of the concerns, in addition to a look at priorities, challenges, opportunities that bring benefits with the application of plastics in the future. However, about the use and disposal that have been increasing, and the need to recycle and reverse this trend, so that they can be considered end-of-life materials, as valuable raw materials for new production, instead of waste.
O que fazer com o lixo lá de casa?
Authors: Souza Claudio Rudinei de , Locatelli Débora Regina Schneider , Korf Eduardo Pavan
Published: October 2023

A partir de um trabalho de conclusão da Engenharia Ambiental e Sanitária da Universidade Federal da Fronteira Sul – Campus Erechim, surgiu esta cartilha sobre compostagem para uso em ambientes escolares como forma de ação de sensibilização e educação ambiental. A cartilha foi elaborada com base em leituras de artigos e a realização de atividades teórico-práticas para poder adaptar o conteúdo para crianças do ensino fundamental. Desejamos que a cartilha possa contribuir para o desenvolvimento da conscientização ambiental para um mundo mais sustentável e menos impactos indesejáveis para as gerações futuras
Komparasi Multi Criteria Decision Making Method Penerimaan Bantuan Siswa Miskin
Authors: Nungsiyati Nungsiyati , Susianto Didi , Sari Noca Yolanda , Mukodimah Siti
Published: October 2023

Poor Student Assistance (BSM) is government assistance in the form of a sum of cash that is given directly to students who come from poor families. BSM recipients are students who have been determined by the Ministry of Education and Culture (Kemdikbud) based on a predetermined mechanism. Assistance provided by the government to students from underprivileged families is not transparent so some BSM are not on target. In an effort to minimize target inaccuracies, a study was made with Multi Criteria Decision Making (MCDM) which is a decision-making method for determining the best alternative out of a number of alternatives based on certain criteria. The ranking of beneficiaries is determined using a comparison of the Simple Additive Weighting Method and the Weighted Product Method, which are the MCDM model. Manual testing was carried out on 5 (five). From the test results of the Simple Additive Weighting Method, Alternative 4 obtained the highest score. While the results of the Weighted Product method test show the highest results in Alternative 3. The difference in the calculation results of the two methods used is influenced by several factors such as the performance rating value of each alternative, the weight of the criteria, and mathematical calculations for each method, and because the criteria used do not have different weights so that the calculation results become less significant.
Usability Analysis using User Experience Questionnare (UEQ) and Concurrent Think Aloud (CTA) on Fintech Bibit Application (Case Study on Bibit Application Users in Denpasar)
Authors: Paramitha AA Istri Ita
Published: October 2023

This study aims to measure and determine the effectiveness, efficiency and user satisfaction of the Bibit fintech application. The results of measurements carried out using Concurrent Think Aloud show that the effectiveness measurement obtains an average result of 90% and the efficiency measurement obtains an average result of 91%. The results of measuring user satisfaction can be obtained from the results of the User Experience Questionnaire aspects of efficiency (1.68) aspects of attractiveness (1.39), perspicuity (1.40), stimulation (1.21) dependability (1.00) and novelty (0.48) . This research shows that the Fintech Seeds application has been effective and efficient in its use, and on user satisfaction it has a positive impression, only that the novelty aspect has neutral results, thus innovation and creativity in development must increase in the future.
Sistem Pendukung Keputusan Penentuan Penerima Bantuan Langsung Tunai Dana Desa Dengan Metode Weight Product
Authors: Kurniawan Rudy , Saputri Tri Aristi
Published: October 2023

Assistance sourced from the Village Fund or more commonly known as the Village Fund BLT includes a type of cash grant to underprivileged residents sourced from village funds. Meanwhile, in Gantimulyo village, the handover of this assistance was given by two methods, namely through account transfers and direct giving. This assistance is intended for underprivileged citizens who have not received any assistance from the government. So far, data collection has been carried out by deliberation of each hamlet to determine the recipients of the assistance, but sometimes there are still errors. Among them, there are still recipients who have received other assistance and underprivileged residents have not been recorded. Therefore, it is necessary to make criteria to collect data to determine the recipients of the assistance program. This research was conducted to determine the decision-making method for determining the criteria for recipients of the BLT-DD program in Gantimulyo village, which later there are criteria that residents must have to be used as a reference so that social jealousy does not arise between community residents. So as to enable the beneficiaries to be effective, efficient and on target. This can be evidenced by none of the citizens protesting and getting more than one favor.
Artificial intelligence (AI) and biomaterials: A perfect BandAId™
Authors: Webster Thomas J
Published: October 2023

Artificial intelligence (AI) and biomaterials: A perfect bandAId™

According to the Webster’s dictionary definition, Artificial Intelligence (AI) is: a branch of computer science dealing with the simulation of intelligent behaviour in computers, and/or the capability of a machine to imitate intelligent human behaviour. (1) Much has already been said about AI and, unfortunately, most of it is negative. (2) From students using ChatGPT to write term papers and college admission essays to AI self- driving cars that can crash and cause injuries (3), AI has certainly received a lot of negative press lately. As usual, however, some of this negative press is by those who are not scientists and do not understand the positive impacts AI can have, especially in medicine.
Collaborative Governance in an Effort to Strengthen the Corporate Social Responsibility Program in the Health Field in the City of Bandung
Authors: Sudrajat Ade , Alamsyah Kamal , Bustomi Thomas
Published: October 2023

This research aims to determine the implementation of the company's Corporate Social Responsibility (CSR) or Environmental Social Responsibility (TJSL) Program in the health sector in Bandung City, which to date has not gone according to expectations. The research method that the author uses in this research is descriptive analysis with a qualitative approach. Data collection was carried out by means of observation, in-depth interviews and documentation studies. Meanwhile, the data analysis technique used was Analytical Hierachy Process (AHP), with the aim of measuring the strength, priority and consistency of various criteria and alternatives in each dimension, namely focusing on collaborative research. Governance is determined by the Context, Driver and Collaboration Dynamics system. The results of the research state that the Corporate Social Responsibility Program in the health sector in Bandung City has been running well. To improve CSR programs more effectively, this can be done by prioritizing Collaborative Process factors which are supported by Drivers, which are also influenced by System Contex. Collaborative Dynamics factor, an important aspect to prioritize is increasing Capacity for Joint Action which is supported by Shared Motivation based on Principled Engagement, then Collaboration Dynamics itself is supported by the existence of Drivers who influence it.System Contextsin this case it influences all factors (collaboration dynamics and drivers). Referring to the findings, aspects that need to be emphasized are attention to Resource Conditions and Socio-economic/Cultural Health & Diversity. This can all be realized well with Network Connectedness, Levels of Conflict/Trust, and Political Dynamics/Power Relations that are in harmony. The appropriate model related to Collaborative Governance as an effort to strengthen the Corporate Social Responsibility program in the health sector in Bandung City is to optimize and modify the model adopted from Emerson & Nabatchi (2015b) and Ansell & Gash (2008). The results of this adoption can in turn become an initial benchmark in implementing other CSR programs or other similar programs, both in the city of Bandung and in other regions.
Strategy for Evaluation of Quality Assurance System Implementation Policies in Increasing the Competitiveness of Private Universities in the City of Bandung
Authors: Supriatna Agus , Harits Benyamin , Azis Yaya Mulyana Abdul
Published: October 2023

The implementation of the Quality Assurance System for Private Universities in the City of Bandung is currently still not effective, in the sense that the implementation of the quality assurance system is not fully in accordance with the quality instruments set by the government. The focus of this research is Policy Evaluation in the implementation of the Quality Assurance System for Private Higher Education in the City of Bandung. The sub-focus of this research is the dimensions that need to be carried out in evaluating quality assurance system implementation policies, namely: administrative evaluation, judicial evaluation and political evaluation. This research uses a qualitative descriptive analysis method and is supported by the SWOT technique. This was chosen with the consideration that actual data can be obtained, being able to study the research problem in depth so that results can be obtained that are in line with expectations. The results of the research show that the implementation of the Quality Assurance System for Private Higher Education in the City of Bandung is still not effective, so policy evaluation is needed through (1) Administrative evaluation taking into account: Effort Evaluation, Performance Evaluation, Adequacy of Performance, Efficiency Evaluation and Process Evaluation, (2) Judicial evaluation by paying attention to: Issues of legal validity, Possible Violations of the Constitution, Possible Violations of the Legal System, Possible Violations of Ethics and State Administration Rules, (3) Political evaluation by paying attention to: Political Process in determining policies, Acceptance of political constituents towards public policies, Implementation Information Technology. The results of the policy evaluation in this research then produced a recommendation strategy regarding the implementation of a higher education quality assurance system that is in accordance with government standards.
THIẾT LẬP QUY TRÌNH TINH SẠCH VÀ NUÔI CẤY TĂNG SINH KHỐI TẾ BÀO GIẾT TỰ NHIÊN PHÂN LẬP TỪ MÁU NGOẠI VI BỆNH NHÂN UNG THƯ TUYẾN TIỀN LIỆT
Authors: Nguyễn Trọng Phúc , Phùng Thế Hải , Nguyễn Hoàng Phương , Nguyễn Ngọc Tuấn , Hoàng Trung Kiên , Lê Việt , Đỗ Anh Tuấn , Lê Văn Đông , Đỗ Khắc Đại
Published: October 2023

Mục tiêu: Thiết lập quy trình tinh sạch tế bào giết tự nhiên (natural killer - NK) và quy trình nuôi cấy tăng sinh tạo khối tế bào NK của bệnh nhân (BN) ung thư tuyến tiền liệt (UTTTL) trong phòng thí nghiệm. Phương pháp nghiên cứu: Phân lập 3 mẫu máu ngoại vi từ BN được chẩn đoán UTTTL được thu thập để tách tế bào đơn nhân và sau đó sử dụng công nghệ hạt siêu nhỏ có từ tính Microbead (hãng Miltenyi/Đức) để tạo khối tế bào NK có độ tinh sạch cao (ngày D0) từ khối tế bào đơn nhân máu ngoại vi (peripheral blood mononuclear cells -  PBMCs) này. Khối tế bào NK sau tinh sạch được chuyển nuôi cấy tăng sinh trong môi trường chuyên biệt KBM (Kohjin-Bio/Nhật Bản) và được thu hoạch ở ngày thứ 14 (D14). Kết quả: Tỷ lệ tinh sạch khối tế bào NK đạt 93,4% ở ngày D0 và 94,9% ở ngày D14; với số lượng tế bào NK đạt 385,3 x 106 tế bào và tăng gấp 192,7 lần so với ngày D0. Kết luận: Chúng tôi đã thiết lập và triển khai thành công quy trình tinh sạch và nuôi cấy tạo khối tế bào NK trên BN UTTTL.
Risk Factors and Outcome of Hyphema in Blunt Injury to Eye
Authors: Jaiswal Ram Kumar , Khanna Vanshika , Wahi Dipti
Published: October 2023

Objectives: To study the causes, associated ocular findings and visual acuity on presentation, complications and visual outcomefollowing treatment in patients of hyphema due to blunt injury.Methods: A retrospective observational study was performed in 80 patients with hyphema due to blunt injury presenting tothe outpatient and emergency department of the tertiary care centre of Gorakhpur, Uttar Pradesh for a period of 6 months. Thegender, age, race, cause of blunt injury resulting in hyphema, eye involved, vision at admission, other associated ophthalmologicalfindings, complications and visual outcomes were noted from the case records of patients. The data was analyzed using SPSSprogramme using the chi-square test.Results: Males were more predominantly affected (88.75%). Half of the patients were aged below 30 years. Sports-related injury(51.25%) was the most common cause for hyphema. Hyphema disappeared within 5 days in 68.5% of patients. Iris injuries werevery commonly associated in the form of mydriasis, iridodialysis. The best corrected vision of 6/18 or better was noted in 46.25%of patients at the last follow-up. The follow-up of these subjects was very poor and thus the incidence of secondary glaucomacould not be established. A significant association was seen between Best corrected visual acuity (BCVA) at presentation andat 6 weeks follow-up (p<0.05).Conclusion: Sports-related injury is the most common cause of hyphema. Good visual recovery, without serious complications,is possible with appropriate and in-time treatment in hyphema patients due to blunt injury.
HPV typing as the method of choice in the prevention and early detection of cervical cancer
Authors: Paunović Vesna , Vlaisavljević Željko , Ilić-Živojinović Jelena , Piškorjanac Silvija , Knežević Miroslav
Published: October 2023

Background: Human papillomavirus (HPV) is recognized as the primary cause of cervical cancer (CC), and significant coexisting factors have also been identified. CC is considered a curable disease because it has a long preinvasive period. It is possible to organize effective screening, and the treatment of preinvasive lesions is successful. Aim: To show the importance of HPV typing in the early detection of premalignant cervical disease. Method: Literature review, synthesis, and extraction of key professional and contemporary literature. Results: Depending on the methods used in identification, the presence of different types of HPV was identified in about 90% of intraepithelial neoplasia and CC samples. HPV genotyping plays an important role in the detection of dysplasia and helps to reduce the number of false-positive Pap test results. Randomized controlled trials have shown that CC screening with HPV testing offers greater protection against cervical precancer and cancer compared with cytology-based screening. To date, it has been proven that HPV 16 and 18 genotypes have the highest oncogenic potential. These two genotypes are responsible for about 70% of all squamous cell carcinomas, 30-40% of vulvar cancers, and about 85% of cervical adenocarcinomas. According to a recent report, 48 (35%) of 139 countries recommended HPV-based cervical screening, with most currently switching from cytology to HPV testing. Conclusion: HPV typing can be of great benefit in the early detection of malignant transformation of infected cells and the prevention of CC.
CẤY CHUYỂN RĂNG TỰ THÂN NGAY SAU NHỔ RĂNG CÓ SỬ DỤNG MẪU MÔ PHỎNG: BÁO CÁO LOẠT CA LÂM SÀNG
Authors: Võ Minh Trí , Trương Nhựt Khuê , Nguyễn Hoàng Nam , Trần Thị Kim Ngọc
Published: October 2023

Đặt vấn đề: Cấy chuyển răng tự thân là một phương pháp điều trị mất răng khi bệnh nhân có một răng cho phù hợp. Mục tiêu nghiên cứu: Đánh giá tỉ lệ thành công về lâm sàng của cấy chuyển răng tự thân vào ổ răng mới nhổ có sử dụng mẫu mô phỏng răng cấy chuyển. Đối tượng và phương pháp nghiên cứu: Nghiên cứu đánh giá 12 bệnh nhân có răng vĩnh viễn có chỉ định nhổ (2 nam và 10 nữ) và được điều trị bằng phương pháp cấy chuyển răng tự thân có dùng mẫu mô phỏng. Độ tuổi trung bình là 23,6 (±4,5) (từ 20-34). Răng cấy chuyển là răng cối lớn thứ ba hàm trên, vùng răng nhận là răng cối lớn thứ nhất hoặc thứ hai hàm dưới. Răng cấy chuyển được cố định bằng dây thép không gỉ vào răng kế cận trong 2 tuần. Sau phẫu thuật, tình trạng răng cấy chuyển được đánh giá qua lâm sàng và phim quanh chóp. Kết quả: Thời gian nằm ngoài ổ của răng cấy chuyển nhỏ hơn 1 phút khi dùng mẫu mô phỏng răng cấy chuyển. Các tiêu chí thành công đạt được trong 11 trên 12 ca, chiếm tỉ lệ 91,6%. Kết luận: Mẫu mô phỏng 3D giúp giảm thời gian ngoài ổ răng của răng cấy chuyển, làm tăng tỉ lệ thành công của kĩ thuật cấy chuyển răng.
NGHIÊN CỨU ĐẶC ĐIỂM VÀ GIÁ TRỊ CỦA HÌNH ẢNH SIÊU ÂM ĐỘNG MẠCH CẢNH TRONG ĐOẠN NGOÀI SỌ TRÊN BỆNH NHÂN NHỒI MÁU NÃO TẠI BỆNH VIỆN ĐA KHOA TRUNG ƯƠNG CẦN THƠ NĂM 2022-2023
Authors: Huỳnh Thị Hiền , Lê Hữu Phước , Nguyễn Hoàng Anh , Huỳnh Minh Phú
Published: October 2023

Đặt vấn đề: Hẹp động mạch cảnh đoạn ngoài sọ là một trong những nguyên nhân chính gây nên nhồi máu não. Chụp cắt lớp vi tính mạch cảnh là phương pháp chẩn đoán sớm tình trạng này. Bên cạnh đó, siêu âm cũng được xem là phương pháp không xâm lấn, sẵn có và ít tốn chi phí. Nghiên cứu được thực hiện nhằm khảo sát đặc điểm hình ảnh siêu âm của mảng xơ vữa tại động mạch cảnh đoạn ngoài sọ và đánh giá tính giá trị của phương pháp này. Mục tiêu nghiên cứu: Mô tả đặc điểm hình ảnh của mảng xơ vữa và giá trị của siêu âm so với cắt lớp vi tính mạch cảnh trong chẩn đoán hẹp động mạch cảnh đoạn ngoài sọ trên bệnh nhân nhồi máu não. Đối tượng và phương pháp nghiên cứu: Mô tả cắt ngang 67 mảng xơ vữa tại động mạch cảnh trong đoạn ngoài sọ trên bệnh nhân nhồi máu não đến điều trị tại Bệnh viện Đa khoa Trung ương Cần Thơ từ 8/2022 – 5/2023. Kết quả: Tỷ lệ hẹp trên 70% của động mạch cảnh trong do mảng xơ vữa trên cắt lớp vi tính mạch cảnh và siêu âm tương ứng là 49,3% và 41,8%. Các mảng xơ vữa này tập trung ở thành gần (86,6%) và hơn một nửa có hình ảnh tăng hồi âm (55,2). Về mẫu hồi âm, gần 2/3 mảng xơ vữa cho thấy đồng nhất (64,2%). Hơn nữa, về bề mặt của mảng xơ vữa cho thấy đều với tỷ lệ là 51,2%. Trong chẩn đoán hẹp động mạch cảnh trong, cả hai phương pháp có tính đồng thuận đáng kể, có ý nghĩa thống kê (Kappa=0,67; p<0,05). Kết luận: Phương pháp Siêu âm là kỹ thuật có tính đồng thuận đáng kể và có ý nghĩa thống kê với cắt lớp vi tính mạch cảnh trong chẩn đoán hẹp do mảng xơ vữa tại vị trí động mạch cảnh trong đoạn ngoài sọ
CHARACTERISTICS AND RESULTS OF TREATMENT OF HYPERTRIGLYCERIDEMIA-INDUCED ACUTE PANCREATITIS AT CAN THO UNIVERSITY OF MEDICINE AND PHARMACY HOSPITAL
Authors: Nguyen Cao Nhat Linh , Nguyen Thai Hoa , Thai Thi Hong Nhung , Pham Van Do
Published: October 2023

Background: After alcohol and gallstones, hypertriglyceridemia is the third most common cause of acute pancreatitis (AP). Hypertriglyceridemia is triglyceridemia concentration >150mg/dl (1.7mmol/l). Severe hypertriglyceridemia >1000mg/dl (11.3 mmol/l) is considered the cause of AP. Objectives: To compare some clinical and subclinical features and results of treatment of AP with two levels of hypertriglyceridemia <11.3mmol/l and >I1.3mmol/l at the Department of General Internal Medicine in Can Tho University of Medicine and Pharmacy Hospital. Materials and methods: This was a cross-sectional descriptive study of 33 patients who were admitted to the hospital with hypertriglyceridemia-induced AP. Results: Clinical symptoms and some laboratory tests did not differ between the two groups. Statistically significant differences occurred in the 2 groups as blood CRP value with p=0.009, low sodium levels 134.22±4.73mmol/l and high BMI levels 26.63±5.15kg/m2 in the group with TG ≥ 11.3 mmol/l. The rate of amylase increased 3 times in the high-TG group was 85.2%. Both groups had elevated glucose and LDH levels respectively, with 10.56±5.13 mmol/l and 310.64±206.01U/L. Ultrasound diagnosis of acute pancreatitis reached 100%, CTSI and BISAP index were high in the group with TG ≥11.3mmol/l. The days of using insulin and staying in the hospital were significantly different, with p=0.004 and p=0.014. Conclusions: Comparing the 2 groups of acute pancreatitis with blood TG <11.3mmol/l and ≥11.3mmol/l, there was no difference in clinical symptoms. Mean values of sodium, BMI and blood CRP (p=0.009) were different between the two groups of acute pancreatitis. Treatment results in days of using insulin and staying in the hospital had statistically significant differences between the 2 groups.
KHẢO SÁT ĐẶC ĐIỂM THỰC VẬT, MÃ VẠCH DNA VÀ SƠ BỘ THÀNH PHẦN HÓA HỌC CỦA CÂY TRÀ DORMOY -CAMELLIA DORMOYANA (PIERRE) SEALY, THEACEAE
Authors: Nguyễn Đỗ Lâm Điền , Dương Nguyên Xuân Lâm
Published: October 2023

Đặt vấn đề: Cây Trà dormoy được trồng nhiều nơi ở Trung Bộ và Nam Bộ Việt Nam. Chiết xuất từ lá có tác dụng tăng đáp ứng miễn dịch, hỗ trợ điều trị HIV/AIDS, nhưng có ít nghiên các nghiên cứu đã được công bố. Mục tiêu nghiên cứu: Khảo sát đặc điểm thực vật, mã vạch DNA để góp phần định danh đúng loài Trà dormoy và sơ bộ thành phần hóa học để góp phần định danh đúng loài Trà dormoy. Đối tượng và phương pháp nghiên cứu: Cây Trà dormoy tươi được thu thập tại huyện Bình Chánh, Thành phố Hồ Chí Minh, được phân tích, mô tả, chụp ảnh các đặc điểm hình thái, giải phẫu, bột dược liệu, kèm phân tích trình tự gen matK và khảo sát sơ bộ thành phần hóa học bằng phương pháp Ciuley có cải tiến. Kết quả: Loài Trà dormoy được định danh dựa trên hình thái và trình tự gen matK xác định tên khoa học là Camellia dormoyana (Pierre) Sealy có đặc điểm hình thái đặc trưng: Nhiều lá đài, cánh hoa và nhị, 6 lá noãn, bầu trên; và sơ bộ thành phần hóa học bao gồm: Tinh dầu, chất béo, steroid, flavonoid, saponin, tannin, carotenoid và coumarin. Kết luận: Nghiên cứu góp phần cung cấp dữ liệu định danh chính xác loài Trà dormoy, đặc điểm giải phẫu thân, lá và thành phần hóa học có trong lá.
Clinical Review of Risk of Nephrotoxicity with Acyclovir Use for Treatment of Herpes Simplex Virus Infections in Neonates and Children
Authors: ElHassan Nahed O. , Crawford Brendan , Alamarat Zain , Painter Jacob T.
Published: October 2023

OBJECTIVE

This study aims to clarify the risk of nephrotoxicity with intravenous use of acyclovir (ACV) for the treatment of neonates (ages <3 months) and children (ages ≥3 months to <12 years) with herpes simplex virus (HSV) infections and to identify gaps in knowledge that could be further investigated.

METHODS

Multiple databases were searched to identify studies on risk of nephrotoxicity with ACV use for treatment of invasive HSV infections, defined as any neonatal infection or HSV encephalitis (HSE) in children.

RESULTS

There were 5 and 14 studies that evaluated the risk of ACV-associated nephrotoxicity in neonates and children, respectively. The US Food and Drug Administration (FDA) delayed the approval of high (HD; 60 mg/kg/day) ACV in neonates secondary to risk of toxicity. Based on our review, the risk of ACV-associated nephrotoxicity was lower in the neonatal compared with the pediatric population. Acyclovir dose >1500 mg/m2, older age, and concomitant use of nephrotoxic drugs were identified as variables that increased the risk of ACV nephrotoxicity in children. Although the FDA has approved the use of HD ACV for the treatment of HSE in children, the American Academy of Pediatrics recommends a lower dose to minimize the risk of toxicity. The efficacy and safety of high vs lower doses of ACV for the management of HSE in children has yet to be evaluated.

CONCLUSIONS

The risk of ACV-associated nephrotoxicity was lower among neonates compared with older children. Future studies are needed to identify the optimal dosage that minimizes toxicities and maximizes the efficacy of ACV in children with HSE.
Young people’s involvement in migration research – opportunities for (re)shaping research priorities and practices
Authors: Spencer Grace , Thompson Jill , Froehlich Fanny , Asafo Divine , Doku Michael Tetteh , Asiamah George , Mornuu Jemima , Kassim Amidatu , Kwankye Stephen Owusu , Dankyi Ernestina
Published: October 2023

Young people are frequently involved in research about their own lives and their contributions to the shaping of research priorities increasingly valued. Recently, young people’s participation in research has been extended to advisory group roles including supporting the planning, design and delivery of projects. Such involvement marks an important shift towards valuing young people’s views on how research should be conducted and is often required as part of research funding processes. In this article, we explore the value and contribution of young people’s involvement in a research project focusing on the livelihoods of young migrants in Ghana and the related possibilities for empowerment. Our collaborations remind us of the pitfalls of working from an adult centric lens, and how this may inadvertently contribute to the reproduction of adult ways of understanding young lives. Here, our project Young Person Advisory Group members share their experiences of being youth advisors – highlighting both challenges and opportunities for young people’s meaningful involvement in research.
Young people and gambling in sub-Saharan Africa: towards a critical research agenda
Authors: Glozah Franklin , Bunn Christopher , Sichali Junious M. , Yendork Joana Salifu , Mtema Otiyela , Udedi Michael , Reith Gerda , McGee Darragh
Published: October 2023

Recent decades have seen gambling become a highly lucrative industry across sub-Saharan Africa. Fuelled by the democratisation of access to digital finance and internet technologies, this gambling boom has been concentrated in Africa’s urban economies, where expanding youth populations are increasingly connected to global circuits of sport, popular culture and speculative forms of consumption. This has engendered growing interest in gambling as a distinct and emerging field of academic enquiry across sub-Saharan Africa. To date, psychiatric, epidemiological and behavioural sciences have provided the dominant frame for measuring the extent of ‘problem gambling’ and addiction, but there remains the need to expand and diversify the field to encompass more critical and interdisciplinary approaches that recognise gambling as a densely significant social and cultural phenomenon. This article aims to provide a point of departure for a critical research agenda on the differentiated impacts of gambling on young people and their communities across the continent.
Young people ‘making it work’ in a changing climate
Authors: Barford Anna , Magimbi Paul , Mugeere Anthony , Nyiraneza Mollen , Isiko Benard , Mankhwazi Charles
Published: October 2023

Globally, young people face weak labour market demand and have been particularly susceptible to recent livelihood stresses and shocks linked to climate change. In this article, we consider what happens when young people face intersecting challenges including climate change. While much of the literature focuses on barriers to work and how to break these, we consider young people’s struggles and successes in securing and maintaining work. The focus is on Uganda, demographically one of the world’s youngest countries and home to a largely ‘underemployed’ cohort of young people. Our findings identify some of the many ways in which climate change disrupts young people’s livelihoods. Young people are already proactively responding to climate change. This points to the need for other actors to learn from young people’s existing endeavours, to build in more support and opportunities, manage risk and insecurity, and construct a more climate change-resilient infrastructure.
Moral philosophy In the Novels Of Deputy Nazir Ahmed
Authors: Rehana Kausar  , Professor Dr. Parveen Akhtar Kalu
Published: October 2023

Nazir Ahmed's novels often encompass a philosophy of ethics that explores the complexities of human behaviour and moral dilemmas in a social and cultural context. Rooted in Islamic ethics and values, his writings explore themes of individual character, social responsibilities, and the tension between tradition and modernity. Nazir Ahmad's characters struggle with moral choices, between virtue, duty, and righteous living. reflect the complexities of achieving His novels highlight the importance of empathy, justice and compassion while criticizing social injustices. Overall, Nazir Ahmed's moral philosophy, as depicted in his novels, tries to reconcile religious principles with the challenges of a changing world, and urges readers to have a higher moral compass. Consider your actions, beliefs, and relationships in light.
Pir Hussamuddin Rashidi's Urdu Literary Services
Authors: Sara Jamali
Published: October 2023

Pir Hussamuddin Rashidi was a famous journalist, historian, scholar and political analyst of his time. He was born on 20th September 1911 in Behman village Near Nusrat Railway Station Taluka Rattodero District Larkana. He was founder member of Sindhi Adabi Board, Urdu College Karachi, Urdu Trust Karachi, Institution of Central and West Asian Studies, Karachi University, Idara-e-Yaadgaar-e-Ghalib etc. He had also been the Chairman of Advisory Council of Sindh University, member of Syndicate of Sindh University. Pir Hussamuddin was basically a historian and it was with reference to history that he viewed other Sciences and Arts.Today Sindhi new generation is treading the path of Scholarship and research in the light of Pir Sahib’s work. Pir Sahib introduced the tradition of modern research in Sindh. The Government of Pakistan, in 1964, conferred on him the literary award Sitaara-e-Imtiaz for his meritorious services in the fields of literature and history. He expired on 1st April 1982. He is buried in the historical graveyard of Makli, Thattaa, Sindh, Pakistan