bluuebunny/crossref_metadata_2025 huggingface dataset:
A Classification of Cloud Services and Their Security Assessment in the Healthcare Industry
Authors:   DKTE Society's Textile & Engineering Institute (An Empowered Autonomous Institute), Ichalkaranji, Khanaj Amruta
Published: May 2024

The role of cloud-based services in healthcare settings is crucial in the 21st century. This paper discusses their advantages and tools in hospitals, clinics, and diagnostic centers, categorizing existing applications and services into data storage, computing power, networking, PaaS, SaaS, data analytics, business intelligence, and project management. It also provides an in-depth analysis of security and risk assessment issues in cloud-based services, supported by case studies. Additionally, it includes a comparative risk analysis diagram of secured versus non-secured cloud systems in healthcare. Finally, the paper concludes with recommendations for future work. Key Words: Healthcare facilities, diagnostic centers, cloud services, information technology systems, security, risk analysis.
AI ASSISTANCE FOR HEALTHCARE USING NLP
Authors:   Department of IT, Mahatma Gandhi Institute of Technology, JNTUH, Hyderabad, India, Divya Dr. N Sree
Published: May 2024

Artificial Intelligence (AI) integration into healthcare has the potential to transform patient care, diagnostics, and treatment. This paper provides a detailed overview of AI support in healthcare, focusing on the intersection of (NLP) Natural Language Processing, (ML) Machine Learning, and (DS) Data Science. By employing the power of these slice- edge technologies, AI can offer intelligent, data- driven results to ameliorate healthcare delivery. Natural Language Processing( NLP) is employed to prize precious perceptivity from medical textbooks, clinical notes, and case records. This enables healthcare providers to more understand patient histories and make informed opinions. Machine literacy ways are abused to prognosticate complaint issues, identify anomalies, and epitomize treatment plans. also, data wisdom plays a vital part in aggregating and analysing large healthcare datasets, icing data security, and maintaining compliance with nonsupervisory norms. The paper explores colorful AI operations in healthcare, similar as automated opinion and triage, medical image analysis, medicine discovery, and patient monitoring. These operations have the eventuality to enhance clinical decision- timber, reduce medical crimes, and ameliorate patientoutcomes.AI backing in healthcare isn't without its challenges, including data sequestration enterprises, the need for robust model interpretability, and ethical considerations. The paper discusses these issues and presents strategies to address them. In conclusion, the integration of AI, NLP, Machine literacy, and Data Science in healthcare has the implicit to marshal in a new period of perfection drug and case- centred care. Then we used SVM Algorithm for training the data set and the delicacy position is 97 percent. This technology confluence is poised to revise healthcare by perfecting opinion delicacy, treatment efficacy-ity, and patient issues while icing data security and ethical use.
Cardamom Plant Disease Detection Approach Using EfficientNet
Authors:   Department of Information Science and Engineering Don Bosco Institute of Technology Bengaluru, Karnataka, India, Neelgar, Dr. Basavaraj
Published: May 2024

Cardamom is a queen of spices. It is indigenously grown in the evergreen forests of Karnataka, Kerala, Tamil Nadu, and the northeastern states of India. India is the third largest producer of cardamom. Plant diseases cause a catastrophic influence on food production safety; they reduce the eminence and quantum of agricultural products. Plant diseases may cause significantly high loss or no harvest in dreadful cases. Various diseases and pests affect the growth of cardamom plants at different stages and crop yields. This study concentrated on two diseases of cardamom plants, Colletotrichum Blight and Phyllosticta Leaf Spot of cardamom and three diseases of grape, Black Rot, ESCA, and Isariopsis Leaf Spot. Various methods have been proposed for plant disease detection, and deep learning has become the preferred method because of its spectacular accomplishment. In this study, U2 -Net was used to remove the unwanted background of an input image by selecting multiscale features. This work proposes a cardamom plant disease detection approach using the EfficientNetV2 model. A comprehensive set of experiments was carried out to ascertain the performance of the proposed approach and compare it with other models such as EfficientNet and Convolutional Neural Network (CNN). The experimental results showed that the proposed approach achieved a detection accuracy of 98.26%. Index Terms — Cardamom plant, deep learning, machine learning, neural networks, plant pathology
Automatic Platform Bridge in Railways
Authors:   JSPM’s Bhivarabai Sawant Institute of Technology and Research, Wagholi, Pune, India, 412207, Patil Vyankatesh
Published: May 2024

The primary aim of the Automatic Railway Bridge System is to assist physically challenged passengers in moving from one platform to another. Crossing the railway track within the station premises poses significant challenges, especially for the handicapped and elderly individuals, who often require assistance from others. In this study, the agents utilize various resources such as train characteristics, driving regulations, and information pertaining to other trains to formulate their action plan. Many elderly individuals suffer from ailments such as leg cramps, walking difficulties, vein issues, and chronic foot pains, making it imperative to address this issue. To tackle this problem, we propose a project involving the implementation of a horizontally adjusted platform connecting both station platforms. This innovation eliminates the need for both adults and children to climb bridges, thereby saving time for passengers and ensuring smoother operations for all. Keywords- Railway Systems, Platform Bridge, IR SENSOR (E18-D80NK Infrared Proximity Sensor), DC Motor.
A Review on Utilization of recycled Aggregate in concrete: Examining the effects of incorporating recycled concrete aggregate or other recycled materials as substitute for natural aggregate in concrete mixtures
Authors:   Department of Civil Engineering Rama University Kanpur UP, Swaroop Balvant
Published: May 2024

In developed countries, concrete is mostly observed as a valuable resource. Recycling efforts have highlighted the importance of maintaining the required compressive strength when using old concrete in new construction. Research shows that compressive strength depends on factors like adhered mortar, water absorption, abrasion resistance, aggregate size, original concrete strength, curing time, replacement ratio, transition zone between old and new concrete, moisture level, impurities, and environmental conditions. While some studies have suggested methods for adopting recycled aggregates into concrete mixes, there's a need for a simple and environmentally friendly approach that considers the percentage of adhered mortar. This project aims to review existing literature on using recycled concrete as aggregates, focusing on compressive strength, and propose a method for incorporating recycled concrete aggregate while maintaining strength. Keywords: Construction and demolished concrete, second generation concrete, Adhere, recycling, workability, recycle aggregate, compressive strength
CONTRIBUTION OF PLASTIC ROAD CONSTRUCTION IN MANAGING NON-BIODEGRADABLE PLASTIC WASTE
Authors:   M. Arch student, School of architecture, IPS Academy, Indore., Likhar Ar. Anushka
Published: May 2024

Waste affects every part of society and is not only environmentally damaging but also expensive. Businesses, local authorities, government and members of the public plays a part in the creation, management and disposal of waste and it is vital that they all recognize the benefits of reducing waste and the roles they must play in doing this. Whilst much attention has been paid to re-use, recycling and waste management, in this research we focus on plastic waste reduction and there is now a need for government and the media to promote the importance of this message solely focusing on use of these plastic generated waste, understanding its composition and properties to be used for road construction. Roads must reliably carry heavy loads, often under challenging environmental and geotechnical condition. It follows that the roads are routinely designed to contain high quality, newly produced materials. This research reviews the use of plastic wate materials in road construction and will give an understanding of plastic waste reduction and reusing it into a durable development. Keywords- Plastic waste, bitumen mixed plastic, reducing environmental impacts
TASK SCHEDULING IN CLOUD COMPUTING: A PRIORITY-BASED HEURISTIC APPROACH
Authors:   Assistant Professor, Guru Nanak Institute of Technology, CSE Department, Hyderabad, K VIGNESHWAR
Published: May 2024

With the rapid development of cloud computing, more and more enterprises would like to upload and store their data in the public cloud. When the parts of the business of an enterprise are purchased by another enterprise, the corresponding data will be transferred to the acquiring enterprise. For the usual case, how to outsource the computation cost of data transfer to the cloud? How to ensure the remote purchased data integrity? Thus, it is important to study provable data possession with outsourced data transfer (DT-PDP). For the first time, we propose the novel concept: DT-PDP. By taking use of DT- PDP, the following three security requirements can be satisfied: (1) the other un-purchased data security of acquired enterprise can be ensured; (2) the purchased data integrity and privacy can be ensured; (3) the data transferability’s computation can be outsourced to the public cloud servers. For the security concept of DT-PDP, we give its motivation, system model and security model. Then, we design a concrete DT-PDP scheme based on the bilinear pairings. At last, we analyze the security, efficiency and flexibility of the concrete DT- PDP scheme. It shows that our scheme is provably secure and efficient.
UNVEILING THE LINK: DOES DIGITAL MARKETING ADOPTION FUEL SUSTAINABLE GROWTH FOR SMEs IN INDONESIA?
Authors: Munawaroh Nuril Aulia , Sudarmiatin Sudarmiatin , Putimelinda Widya
Published: May 2024

The research indicates that the adoption of digital marketing among SMEs in Indonesia significantly contributes to their sustainable growth. The study identifies several key factors that influence this relationship, including attitude toward digital marketing, perceived behavioral control, subjective norm, intention to use digital marketing, and actual use of digital marketing. Specifically, the study highlights that positive attitudes towards digital marketing and subjective norms directly influence the intention to use digital marketing, which subsequently impacts the actual adoption of digital marketing tools. Moreover, the study underscores that the actual use of digital marketing has a direct positive effect on the sustainable growth of SMEs. These findings affirm the potential of digital marketing as a valuable resource for enhancing the sustainable growth of SMEs in Indonesia. By comprehending the factors that drive the adoption and utilization of digital marketing, businesses can develop effective strategies to promote sustainable growth.
ANALISIS PENGARUH DANA BAGI HASIL TERHADAP PENERIMAAN DANA PERIMBANGAN KABUPATEN NABIRE
Authors: Sada Oskar
Published: May 2024

Penelitian ini bertujuan Untuk mengetahui Pengaruh Dana Bagi Hasil terhadap Penerimaan Dana Perimbangan Kabupaten Nabire selama  2008-2012 dan Untuk mengetahui Faktor-faktor apa saja yang dapat mempengaruhi Dana Bagi Hasil di Kabupaten Nabire. Penelitian ini menggunakan analisa data kuantitatif agar dapat menyelesaikan masalah yang diangkat dalam penelitian ini. Hasil penelitian mengungkapkan bahwa Nilai koefisien korelasi (r) yang diperoleh adalah 0,240 atau 24,,20 persen. Dengan demiokian hasil ini menunjukkan bahwa terdapat hubungan antara Dana Bagi Hasil terhadap Dana Perimbangan Kabupaten Nabire, walaupun kecil hasilnya, Sedangkan Nilai determinan (r²) yang di peroleh sebesar 0,058 atau 05,80 persen. Dan hasil ini menunjukan bahwa Dana perimbangan yang diterima dari Dana Bagi Hasil sebesar 05,80 persen. Sedangkan sisanya 94,2 persen diperoleh dari pos-pos lain yang turut meningkatkan Penerimahan Dana perimbangan Kabupaten Nabire; Penerimaan Dana Bagi Hasil Kabupaten Nabire kurun waktu lima tahun terakhi dari tahun 2008 – 2012 mengalami fuktuasi yang mana disebabkan oleh beberapa faktor – faktor yang penulis sudah utarakan pada bab pembahasan.
Pengaruh Disiplin Kerja Terhadapat Kinerja Aparatur Sipil Negara Pada Distrik Abepura Kota Jayapura
Authors: Lobubun Munawir
Published: May 2024

Tujuan penelitian inin yaitu untuk mengetahui pengaruh disiplin kerja secara terhadap kinerja aparatur sipil Negara pada distrik Jayapura Selatan Kota Jayapura. Populasi dan sampel penelitian ini sebanyak 31 orang aparatur sipil Negara dengan menggunakan analisi regresi linear sederhana. Hasil analisi menunjukkan bahwa: nilai t tabel (5.927 > 1,699) dan siginifikannya 0,000 < 0,05. Koefisien koleralasi sebesar 0,740 atau 74,0 dan koefisien determinasi sebesar 0,548 atau 54,8%. Hal ini menujukkan bahwa terdapat hubungan yang kuat antara varibel disiplin kerja dan variabel kinerja terhadap  kinerja.
Determination of Seed Germination and Seedling Characteristics of Amygdalus orientalis (Mill) and Amygdalus turcomanica (Lincz) Almond Species
Authors: Beyazit Safder , Çalışkan Oğuzhan
Published: May 2024

This study was conducted to determine the seed germination and seedling characteristics of 13 genotypes for Amygdalus orientalis (Mill) and 8 genotypes for Amygdalus turcomanica (Lincz) selected from Southeastern Anatolia region of Türkiye. Stratification time (days), germination rate (%), the emergence rate (%), the emergence time (%), seedling length (cm), stem diameter (cm), the length of internodes, and branching status were examined in two wild almond species. The highest germination rates were obtained from O13 genotype (79.50%) of A. orientalis and T8 genotype (84.76%) of A. turcomanica. The emergence rates ranged from 49.4% (O4) to 85.69% (O12) in A. orientalis (Mill) genotypes and ranged from 57.16% (T1) and 75.00% (T8) in A. turcomanica (Lincz) genotypes. Emergence duration varied between 10 and 31 days in A. orientalis (Mill) genotypes and between 13 and 28 days in A. turcomanica (Lincz) genotypes. These results demostreated that seedling length varied between 21.95 cm and 48.50 cm, stem diameter between 2.30 mm and 5.09 mm in A. orientalis (Mill) genotypes, whereas seedling length ranged from 12.05 cm to 30.88 cm and stem diameter ranged from 2.22 mm to 3.29 mm in A. turcomanica (Lincz) genotypes.
Effectiveness of Educational Intervention Based on Academic Stress and Emotional Intelligence among Senior Secondary School Students of Dibrugarh Town (Assam)
Authors: Sinha Sandip , Yaja Hage , Hernwal D. S.
Published: May 2024

Average performance of school students and increasing dropout rates are major problems in our country. A poor academic performance and other curricular activities generate negative emotions in young people and results in academic stressors and degrading emotional intelligence. The study aimed to analyze the repercussions of academic stressors on ability to perform among students, to differentiate between academic stress (AS) and emotional intelligence (EI) among students, and finally to establish the impression of EI in this context. A descriptive correlation study involving senior secondary school students of Dibrugarh Town (Assam) affiliated to Secondary Education Board of Assam (SEBA) and CBSE respectively. The sample consisted of 422 students (Boys-209, Girls-213) aging between 14-18 years, who responded through a questionnaire for evaluating the variables of study. The study traced a relationship between both variables among the students. AS and EI of subjects is nearly normally distributed, boys have shown higher AS compared to girls, whereas girls have shown higher EI than boys drawing towards a negative co-relation between AS and EI, respectively.
Isolation and Diagnosis of the Myxozoa Parasitizing in some Fish Species in Tigris River at Salah Al-Din Governorate, Iraq
Authors: Jasim Al-Shaima M. , Abdullah Abdullah H. , Khlaf Waser Saad
Published: May 2024

The currently study was achieved from February 2021 to end January 2022 to investigate the external and intestinal parasites in some fish species of Tigris river passing Tikrit city. During the period of this study, 580 fish were collected that belonged to seven families and 16 species. These fish are represented 45 Acanthobrama marmid, 40 Alburnus sellal, 30 Arabibarbus grypus, 65 Carasobarbus luteus, 55 Chondrostoma regium, 60 Cyprinion kais, 60 Cyprinius carpio, 50 Leuciscus vorax, 21 Luciobarbus xanthopterus, 14 Squalius Lepidus, 13 Mystus pelusius, 10 Silurus triostegus, 10 Heterropneutes fossilis, 12 Mastacembelus mastacemblus, 30 Coptodon zilli and 65 Planiliza abu.
 This study diagnosis 12 species of Myxoblus: M. bouixi, M. bramae, M. branchiophilus, M. cyprinicola, M. dispar, M. ellipsoides, M. infundibulatus, M. koi, M. magnus, M. molnari, M. musculi, and M. shaerica.
EMERGENCE OF CEFTAZIDIME-AVIBACTAM RESISTANCE IN ENTERO-BACTERALES AND PSEUDOMONAS AERUGINOSA
Authors: Mehwish Alina , Iftikhar Irim
Published: May 2024

Objective: The objective of this study is to determine the emergence of resistance to Ceftazidime-Avibactam (CAZ-AVI) by Enterobacterales and Pseudomonas aeruginosa in clinical isolates.
Material and Methods: In this cross-sectional study (6-months) March-August 2022 Carbapenem resistant Enterobacterales were tested for Ceftazidime-Avibactam (30/20 µg, Oxoid Pvt Ltd) using Disk diffusion technique and enzymes were identified in resistant strains by Carbapenem Inactivation Method (mCIM, eCIM) as per CLSI M100 Guidelines 2022.
Results: CAZ-AVI effectiveness has greatly decreased among Enterobacterales and P. aeruginosa isolates in recent past. Antimicrobial susceptibility testing results were interpreted using CLSI M100 document. Resistance against CAZ-AVI in Enterobacterales was found to be 80.8 % in E. coli and 72.1% in Klebsiella pneumonia isolates. This higher emergence is associated with CRE isolates majorly comprising MBLs in our country. Moreover, it has been observed that Metallo- β-lactamases mediated enzyme resistance is one of the major resistance patterns followed by serine carbapenemases.
Conclusion: The high frequency of resistance 77% was observed against CAZ-AVI in CRE and in CRPA, the resistance is 80.1% respectively. In our country this tremendously increase in CAZ-AVI resistance is attributed to the existence of NDM in the region.
Keywords: Carbapenem Resistant Enterobacterales (CRE), Metallo beta lactamases (MBLs), Carbapenem Resistant Pseudomonas aeruginosa (CRPA) Ceftazidime-Avibactam (CAZ-AVI), Modified Carbapenem Inactivation Method (mCIM), EDTA-modified Carbapenem Inactivation Method(eCIM), Multiple Drug Resistance (MDR)
CHARACTERIZATION OF NEONATAL THROMBOCYTOPENIA AT TEACHING HOSPITAL OF RAHIM YAR KHAN
Authors: Ghafoor Muhammad Bilal , Sarwar Faiza , Tayyab Hafiz Muhammad , Waseem Samina , Khanzada Farhan Ali , Mehmood Amna
Published: May 2024

Objective: To determine the prevalence and characterization of thrombocytopenia in neonates and the pattern of illnesses in these thrombocytopenic neonates.
Material and Methods: A cross sectional study was conducted on 400 neonates in Pathology and Pediatric departments of Sheikh Zayed Medical College/Hospital, Rahim Yar Khan, from November 2022 to July 2023. Analysis of data was done by using SPSS 23.
Results: Out of 400 studied neonates, males made up 238 (59.5%), while females were 162 (40.5%). Thrombocytopenic neonates were 76(19%) while 324(81%) neonates had normal platelet count. Out of the 76 thrombocytopenic neonates, 42(10.5%) neonates had mild thrombocytopenia, 25(6.25%) had moderate thrombocytopenia and 9 (2.25%) had severe thrombocytopenia. Degree of thrombocytopenia revealed that 46 (11.5%) of neonates had thrombocytopenia in late onset phase while 30 (7.5%) had early onset thrombocytopenia. Correlation of thrombocytopenia with several disorders displayed that neonatal sepsis and anemia were significantly linked with thrombocytopenia, followed by birth asphyxia, neonatal birth in preterm and full-term neonates, low birth weight and Neonatal jaundice, furthermore, the p-value for bleeding in neonates allied with thrombocytopenia was found significant with value of 0.03.
Conclusion: The current study discovered that mild thrombocytopenia among neonates is frequent followed by moderate and severe. Thrombocytopenia has strong correlation with neonatal sepsis, anemia, birth asphyxia, neonatal birth (pre term, full term) and bleeding. Severe thrombocytopenia can be used as a prognostic indicator in sick neonates. Hence thrombocytopenia is a frequent challenge for neonatologists to cope the serious consequences of neonatal health.  
Keywords: Neonatal thrombocytopenia, Platelet, Low birth weight neonates, Sepsis, Asphyxia.
ASSOCIATION OF THE PRESENCE OF BCR-ABL1 GENE REARRANGEMENTS AND MYELOID ABERRANT ANTIGENS IN PRECURSOR B-ACUTE LYMPHOBLASTIC LEUKEMIA (PRE-B-ALL) PATIENTS
Authors: Younas Ayesha , Imtiaz Isma , Awan Mohammad Jamil , Imran Ayisha , Nazir Touqeer , Malik Noman Aslam
Published: May 2024

Objective: To determine the association of the presence of BCR-ABL1 gene rearrangements and myeloid aberrant antigens in precursor B-ALL patients.
Material and Methods: Both males and females, of all age groups, diagnosed with precursor B-ALL on flow cytometry were included in the study. BCR-ABL1 gene rearrangement was identified by performing Fluorescence in situ hybridization (FISH) using Vysis LSI BCR/ABL, Dual color, Dual fusion translocation probe set. The results were noted and compared with the results of flow cytometry.
Results: Male patients were 36 (60%) and female patients were 24 (40%) out of total 60 patients. Median age was 22 years (range 1-73). BCR-ABL1 fusion gene was identified in 47 (78%) patients while 13 (22%) patients were negative for BCR-ABL1. Aberrant myeloid antigens were expressed in 24 (40%) patients and all of these patients were BCR-ABL1 positive. None of BCR-ABL1 negative patients expressed aberrant antigens. There was statistically significant association between BCR-ABL1 positivity and CD117 expression (P<0.05).
Conclusion: 
Keywords: BCR-ABL1, Pre B-ALL, Myeloid aberrant antigens, Flow cytometry, FISH.
The clinical significance of CRP and IL-6 in early recognition of neonatal sepsis
Authors: Aslam Farheen , Sipra Muhammad Wajid Khurshid , Zakir Faizan Ahmed , Anwar Zain Ul Abeden , Shaukat Asma
Published: May 2024

Objective: The aim of this study was to determine serum CRP and IL-6 levels in confirmed and clinically suspected groups of neonatal sepsis and these biochemical parameters are being compared with blood culture of neonates with clinical signs and symptoms of sepsis.
Material and Methods: The samples of 180 suspected cases of neonatal sepsis were sent to pathology department. Out of them 92 were proven positive for blood culture and were considered as confirmed septic group while rests were included in clinically suspected group. Blood culture was performed on BACT/ALERT® 3D. Serum CRP was performed by immunoturidimetric method on AU 680 Beckman Coulter and IL-6 measurement was done on Access 2.
Results: The serum CRP and IL-6 levels were higher in confirmed sepsis group and their levels were in correspondence to severity of infection. At cut off values of >10mg/L, CRP showed sensitivity of 94%, and specificity of 74% while at cut off of >35ng/L, IL-6 had sensitivity and specificity of 70% and 88% respectively.
Conclusion: The results of this study suggested that CRP was a highly sensitive marker and IL-6 was a more specific for detection of neonatal sepsis.
Keywords: neonatal sepsis, CRP, IL-6
Frequency of loss of calretinin expression in clinically susceptible cases of Hirschprung disease in rectal biopsies
Authors: Haider Ayesha , Jamil Unaiza , Shah Iqra Ahmad , Aslam Maria , Mumtaz Kiran , Hamdani Syed Naeem Raza
Published: May 2024

Objective: To determine the frequency of loss of calretinin expression in clinically susceptible cases of Hirschprung disease in rectal biopsies.
Material and Methods: This descriptive, cross-sectional study was conducted at Department of Histopathology, Combined Military Hospital, Multan for a period of 6 months (17th Oct 2021 to 16th April 2022). A total 93 suspected cases of Hirschprung disease were taken. Specimens received in 10 % buffered formalin and fulfilling inclusion criteria were included in the study. The cases diagnosed as Hirschprung disease were taken and calretinin immunohistochemical stain was applied and result recorded after evaluation by consultant histopathologist. Data was analyzed using (Statistical Software for Social Sciences (SPSS) version 19).
Results: Out of 93 cases, 67 (72.0%) were male patients, whereas 26 (28.0%) were female patients. The average age of the study participants was 7.95 months, with a minimum age of 1 month and a maximum age of 12 months. Twenty-eight (30.1%) of the 93 study cases were from rural areas, while 65 (69.9%) were from metropolitan areas. Twenty-five families (26.9%) reported monthly incomes of up to Rs. 35000, while 68 families (73.1%) reported incomes of over Rs. 35,000. Of these 93 study cases, failure to pass meconium was noted in 24 (25.8%) patients, constipation was noted in 75 (80.6%) and abdominal distension was noted in 62 (66.7%) patients. Loss of calretinin expression was noted in 34 (36.6%) of our study cases. 
Conclusion: According to the findings of our investigation, calretinin is very helpful in identifying suspicious cases of Hirschsprung disease. When acetylcholinesterase enzyme histochemistry is not accessible, it can be a helpful, cost-effective diagnostic assistance in centers with limited resources. It is a reliable and efficient diagnostic tool for early diagnosis of the illness. Loss of Calretinin expression was significantly associated with age and residential status.
Keywords: Calretinin expression, Frequency, Hirschsprung disease, Immunohistochemistry
Phlebotomy- A gateway to laboratory diagnostics
Authors: Alizai Shehla Ambreen , Sadaf Rabia , Atif Maleeha , Shehzadi Kanwal , Noor Naima , Saeed Muhammad
Published: May 2024

Objective: To assess the knowledge, practice and attitude about venipuncture amongst Nursing staff of a tertiary care hospital.
Material and Methods: This questionnaire-based survey was done at Rawal General and dental hospital, Islamabad, from January to April 2022. The Questionnaire was developed as per the CLSI H3-A6 and WHO‘s venipuncture guidelines. It was distributed to nursing staff by hand. Most were filled inside the classes in front of the teacher. 
Results: The frequency of correct responses in the knowledge section varied from 4(4.6%) about the number of tube inversions to 79(90.8%) about wearing of gloves before taking a sample while 47(54%) selected the correct option of identifying a patient. Regarding the standard phlebotomy protocols, the response was quite low which was 26(29.9%), 18(20.7%) and 8(9.2%) about the correct angle of needle insertion, what to inspect of the supplies and the location of applying the tourniquet respectively. Recapping with two hands is still done by 13% and 79% still put the sample by holding tube in the other hand. In spite of all this 66% still think that one can learn venipuncture by practicing the techniques without going through a proper course. 
Conclusion: Nursing staff in Rawal General and dental hospital is not fully aware about basic laboratory protocols and their importance. This unawareness can lead to generation of erroneous lab reports. Formal education, training with summative assessments should be a part of the curriculum of nursing courses followed by rigorous implementation monitoring.  
Keywords: Awareness, Nurses, Phlebotomy, Venipuncture, Sample
Unveiling colistin resistance in extensively drug-resistant microorganisms among ICU patients of tertiary care hospital Karachi, Pakistan
Authors: Talib Sadia , Ahmed Abeera , Abid Syeda Hira , Assad Tahira , Nizamuddin Muhammad , Sharif Shaista
Published: May 2024

Objective: To determine the prevalence of extensively drug-resistant (XDR) microorganisms in the intensive care unit (ICU) of a tertiary care hospital in Karachi and to identify the presence of colistin resistance (CLR) among these XDR isolates.
Material and Methods: A cross sectional study was carried out in the ICU of a tertiary care hospital from August 2022 to February 2023 and various clinical samples of XDR Gram negative bacilli (GNB) were collected from ICU. These specimens were processed by following the guidelines established by the Clinical and Laboratory Standards Institute (CLSI), Agar and broth microdilution methods were used to assess the colistin susceptibility of XDR isolates.
Results: The study focused on 100 extensively drug-resistant (XDR) specimens. K. Pneumoniae dominated (32%), followed by E. coli (23). Among the 100 XDR, 89% were colistin susceptible, and 11% were resistant, tested by agar and broth microdilution. Of the 11% CLR, P. aeruginosa was most common, with the highest resistance in urine specimens. Colistin resistance was highest for P. aeruginosa (45%), followed by A. baumannii (18%), E. coli (18%), K. Pneumoniae (9%), and K. oxytoca (9%). CLR isolates were mainly (27%) from urine.
Conclusion: Prolonged hospital stays and antibiotic pressure can lead to CLR development. Labs should monitor XDR closely, implementing measures to minimize antibiotic resistance. Controlling colistin resistance through stewardship is crucial.
Keywords: Extensively drug resistant, Colistin resistant, Minimum inhibitory concentration, Nasobronchial lavage
Sports Development Program: The Case of Technical Vocational High School in the Province of Sorsogon, Philippines
Authors:   Sorsogon State University, Graduate School, Sorsogon City, Philippines, P. Ebio Ma. Jesusa , S. Digo Gerry ,   Sorsogon State University, Graduate School, Sorsogon City, Philippines
Published: May 2024

Sports, as one of the extracurriculars in the school, has a significant impact on the development of the youth. The school is an avenue to give students opportunities to improve their physical health and well-being. The purpose of this study is to determine the status, strengths, and weaknesses of the sports development program (SDP) of a technical vocational high school in the Province of Sorsogon, Philippines. This study utilized the convergent mixed method of research using a survey, unstructured interviews, focus group discussions, and documentary analysis. The respondents included two school administrators, twelve teacher coaches, and seventy-four student-athletes. The study’s findings provided an in-depth analysis of the status in terms of athlete development, staff development, facilities and equipment, and the school administrator’s support for the SDP. The qualitative findings concorded on the development program and strength of the SDP, discorded on the facilities and weaknesses of the SDP, and expanded on athlete development, equipment, and the support of the school administrator for the SDP. Furthermore, this study provided a comprehensive understanding of the SDP’s status, strengths, and weaknesses, guiding the development of a new sports development program with policies and procedures to address the challenges faced by the current SDP.
Marketing Mix Strategy (7P) in Increasing Community Interest at Man 1 Trenggalek
Authors:   UIN Sayyid Ali Rahmatullah (SATU) Tulungagung, East Java, Indonesia, Arlina Ulik , Sujianto Agus Eko ,   UIN Sayyid Ali Rahmatullah (SATU) Tulungagung, East Java, Indonesia, Mutohar Prim Masrokan ,   UIN Sayyid Ali Rahmatullah (SATU) Tulungagung, East Java, Indonesia
Published: May 2024

Madrasahs continue to improve the quality of their education in the competition to attract the public. This is also done by MAN 1 Trenggalek which has strategies for increasing the number of quality students. This research aims to describe in depth the marketing mix (7P) strategy of MAN 1 Trenggalek in increasing public interest. Researchers use qualitative research. Data collection techniques are in-depth interviews, participant observation and documentation. Data analysis starts from data condensation, data presentation, verification and drawing conclusions. The results of the research show that the marketing mix strategy (7P) is: 1) The products being marketed are quality madrasah graduates, able to compete and can be accepted at State Universities, State Islamic Universities, Service Schools, TNI/POLRI, Tahfidzul Qur’ Islamic Boarding Schools an, and able to be absorbed into the world of work. 2) The price offered is an affordable education fee that does not burden the students’ parents, there is PIP, the education fee is IDR 0.- (rupiah) for those who do not have PIP but have one of the welfare cards. Rewards from the madrasa committee for outstanding students. 3) The madrasa marketing place is a strategic madrasa location in the central area of ​​Trenggalek Regency, close to the Trenggalek stadium, several Islamic boarding schools and other important places. 4) Promotion/promotion by introducing and showing the advantages of the madrasah to prospective students and parents via social media within the network (IG, Tiktok, Web and others) and outside the network by participating in competitions at district, provincial and national levels. 5) People in marketing madrasa education services are qualified educators, well-dressed, polite, neat and friendly. Madrasah Committee, Parents and people who have good hopes for the development of the madrasah. 6) Process/The marketing process is good communication between all madrasa parties jointly marketing by carrying out the stages of planning, organizing, implementing and evaluating. 7) Physical Evidence/Physical Evidence consists of representative learning rooms, 3 language laboratories, computer laboratories, libraries, halls, teachers’ rooms, TU rooms, UKS, canteen and sports fields.
Abordagem da musicoterapia na reabilitação social de pacientes com o transtorno do espectro autista
Authors: Soares Roldão da Mota , Raimundo Ronney Jorge de Souza
Published: May 2024

Introdução: O Transtorno do Espectro Autista (TEA) afeta aprendizagem, comunicação e interação social ao longo da vida, com prevalência global de uma em cada 160 crianças, diagnosticado pelo DSM-V. A etiologia envolve fatores genéticos, ambientais e biológicos. A música é uma ferramenta essencial na comunicação não-verbal para pessoas com TEA, facilitando conexões emocionais e interpessoais. A musicoterapia estimula habilidades cognitivas, emocionais e sociais, com benefícios na saúde física, mental e emocional, promovendo relacionamentos interpessoais e controle emocional. Estudos indicam seu papel fundamental na promoção da saúde mental e reintegração social de indivíduos com TEA. Objetivo: Investigar o impacto da musicoterapia na reabilitação social de pacientes com TEA, examinando seus efeitos na saúde mental, no desenvolvimento socioemocional e na reintegração à sociedade. Metodologia: Foi realizada com base em artigos científicos publicados nos últimos cinco anos. Identificou-se 45 artigos sobre o tema, encontrados em diferentes fontes acadêmicas, após uma análise, 37 artigos foram excluídos. No final, restaram 8 artigos que foram selecionados para a revisão sistemática. Resultados: Ressalta-se que, diante das análises dos estudos elencados, persistem desafios metodológicos e lacunas de conhecimento que exigem atenção contínua da comunidade científica. A necessidade de estudos com desenhos robustos, amostras diversificadas e medidas objetivas de eficácia permanece evidente, conforme ressaltado por diversos autores. Conclusão: Destaca-se que, embora a musicoterapia represente uma importante intervenção terapêutica para indivíduos com TEA, faz-se necessário continuar avançando no conhecimento científico e na prática clínica para otimizar seu impacto e alcance na reabilitação social desses pacientes.
Influência do clareamento interno na resistência à fratura coronária com diferentes estratégias restauradoras
Authors: Souza Elisângela Maria Pereira de , Gelio Mariana Bena , Zaniboni Joissi Ferrari , Besegato João Felipe , Saad José Roberto Cury , Kuga Milton Carlos , Andrade Marcelo Ferrarezi de , Santos José Rodolfo Estruc Verbicário dos
Published: May 2024

Objetivo: Avaliar diferentes métodos de clareamento dental intracoronário com percarbonato de sódio ou perborato de sódio associado ao uso de água destilada (DW) ou peróxido de hidrogênio (HP), avaliando a resistência a fratura em dentes restaurados com resina composta (RC) ou cimento de ionômero de vidro (CIV). Materiais e métodos: Sessenta dentes bovinos extraídos foram divididos em quatro grupos experimentais e dois controles (n = 10) após o tratamento endodôntico. Após a obturação do canal radicular, uma barreira de ionômero de vidro foi realizada na junção cemento-esmalte. Depois disso, as câmaras pulpares foram preenchidas com: G1: restauração com RC; G2: restauração com CIV; G3: Perborato de sódio + DW + restauração com RC; G4: Perborato de sódio + HP + restauração com RC; G5: Percarbonato de sódio + DW + restauração com CIV; G6: Percarbonato de sódio + HP + restauração com CIV. Os agentes clareadores foram substituídos após 7 dias, e os dentes foram mantidos em saliva artificial por mais 7 dias, após os quais as pastas foram removidas e as cavidades de acesso coronário foram restauradas com ionômero de vidro. As coroas foram submetidas a carga de compressão a uma velocidade de cabeça cruzada de 0,5 mm/min posicionada a 135° ao eixo longo da raiz por uma máquina de teste EMIC até a fratura coronária. Os dados foram analisados estatisticamente pelo teste ANOVA e Tukey (p=0,05). Resultados:  Não foram observadas diferenças na resistência à fratura entre os grupos experimentais (P>0,05). Conclusão: Aguardar sete dias para realizar a restauração final após o clareamento interno favorece a resistência a fratura do elemento dentário
Effects of polishing or glazing on surface roughness and microhardness after milling CAD-CAM ceramic materials
Authors: Manso Rafael Wallace Cordeiro , Silva Aryvelto Miranda , Zaniboni Joissi Ferrari , Gelio Mariana Bena , Campos Edson Alves de
Published: May 2024

Objective: This study aimed to evaluate the surface roughness and microhardness of CAD-CAM ceramic blocks after different surface finishing protocols. Materials and methods: Three ceramics were evaluated: lithium disilicate, leucite-reinforced feldspathic and zirconia-reinforced lithium silicate. Ninety specimens were obtained and distributed into 3 groups (n=10): polishing (specimens were polished with an abrasive rubber kit); conventional glaze (according to the manufacturer's recommendations); and, extended glaze (the specimens were kept for 15 minutes at maximum firing temperature and the furnace was kept closed until reaching 200ºC). In all specimens, a drill was used to simulate the milling machine and thus obtain the initial roughness. Surface roughness was evaluated before and after the finishing protocols, while Vickers microhardness was performed only after the finishing protocols. Roughness data were analyzed to repeated measures two-way ANOVA and Bonferroni post-hoc test and ANOVA with Welch correction and Games-Howell test were used to analyze microhardness data (α = 0.05). Results: Both conventional and extended glazes showed greater smoothness for lithium disilicate and zirconia-reinforced lithium silicate ceramics, while for Empress, extended firing of the glaze provided greater surface smoothness. Regarding microhardness, there was no statistically significant difference among the protocols for the same material. The conventional glaze group made from lithium disilicate did not show a significant difference in microhardness values in relation to the other groups. Conclusion: The application of glaze improves the surface smoothness of the ceramics after milling procedure. There is no change in microhardness with different surface finishing protocols.
Avaliação da qualidade de vida e condições de trabalho em professores do ensino público
Authors: Matos Tallys Newton Fernandes de , Catrib Ana Maria Fontenelle , Sampaio Patrícia Passos , Caldas José Manuel Peixoto , Barros Maria José Matos de
Published: May 2024

O trabalho envolve um significado amplo e se relaciona com o desenvolvimento de atividades para buscar benefícios sociais, políticos, psicológicos e econômicos. É identificado como fator de saúde e adoecimento representando qualidade de vida. O professor ganha destaque por executar uma atividade que requer condições para o desenvolvimento da prática. Com isso, o objetivo geral foi avaliar a qualidade de vida e condições de trabalho em professores do ensino público na cidade de Limoeiro do Norte, Ceará. O presente estudo é quantitativo do tipo transversal e analítico. A população estudada foi a dos professores da rede pública de Limoeiro do Norte, no Ceará. A amostra foi composta por 170 professores distribuídos proporcionalmente nas redes de ensino municipal, com representação de 95% de confiança. As ferramentas utilizadas foram a “Escala de Avaliação do Contexto do Trabalho” e a “Escala de Qualidade de vida da Organização Mundial de Saúde”. Os dados foram analisados pelo programa SPSS (Statistical Package for the Social Sciences) versão 20.0. Os resultados mostraram que as condições de trabalho e organização do trabalho são precárias, possibilitando relações profissionais satisfatórias como possível estratégia de enfrentamento deste contexto.  A qualidade de vida apontada como satisfatória, apresentou alterações no que se refere à insatisfação com a remuneração, tempo para lazer e acesso a saúde. Com isso, é importante que intervenções que possibilitem a transformação deste cenário através de políticas públicas como estratégia na promoção da saúde.
Experiência, inclusão escolar e pandemia: desafiando os limites da aprendizagem a partir da experiência dos alunos em tempos de ensino remoto e híbrido
Authors: Santos Antonio Nacílio Sousa dos , Arruda Ítalo Rodrigo Paulino de , Azevedo Luiz Felipe Araújo , Sousa Carlos Augusto Marinho de , Cezario Danilo de Sousa , Neves Carlos Rigor , Lima Emerson Rodrigues , Melo Tatiani Cristina de Santana , Pessoa Ismael de Alencar , Silva Rivaldo Ferreira da
Published: May 2024

O presente estudo propõe uma análise conduzida em duas instituições de ensino público localizadas no Estado do Ceará, englobando estudantes de diferentes séries do ensino médio. A pesquisa se configura como sendo de cunho qualitativa (Minayo, 2016) com viés compreensivo (Weber, 1999) Os dados foram obtidos por meio de um questionário disponibilizado através do aplicativo Google Forms, distribuído nos grupos de WhatsApp das referidas escolas. Composto por perguntas abertas, o questionário contou com a participação de cerca de 50 discentes. O objetivo primordial consistiu em avaliar a experiência dos alunos durante o período das aulas remotas e híbridas, em duas instituições de ensino no Estado do Ceará. A problemática subjacente a esta pesquisa reside em compreender como a experiência do ensino remoto e híbrido foi agenciado por estes estudantes. Desse modo, procuramos compreender, a partir de uma perspectiva humanizada, os impactos da pandemia na vida e na dinâmica da comunidade escolar, além de investigar a eficácia das aulas ministradas de forma remota. Indagamos: quais as afetações que a pandemia trouxe no processo de aprendizagem dos participantes? Os resultados obtidos indicam a existência de múltiplas consequências negativas no ensino-aprendizagem, enfatizando a importância de manter um ambiente de diálogo e respeito, uma vez que as afetações destacam a complexidade das experiências dos estudantes durante o período da pandemia e a importância de abordar suas necessidades individuais ao planejar e implementar estratégias de ensino híbrido ou remoto.
BIOMARKER «PEAK HEIGHT VELOCITY» AS THE INDICATOR OF SECULAR DYNAMICS OF PHYSICAL STATUS IN INTERGROUP STUDIES/COMPARISONS
Authors: FEDOTOVA T.K. , GORBACHEVA A.K.
Published: May 2024

Introduction. The goal of study is the estimation of «peak height velocity» (PHV) as the marker of secular trends in addition to secular dynamics of height (H). Material and methods. The study embraces the block of samples of scholars (6/7-17 years) from Russia and former USSR, examined through the vast historical period from 1920th till nowadays, literary data and personal archives of the authors. The main attention is paid to three urban agglomerations - Moscow, Nizhniy Novgorod, Minsk. The following number of parameters is determined for each sample: the age of maximal velocity of growth dynamics of average levels of H during adolescence (APHV), determined according to the empirical patterns of annual changes of average H levels and consequent smoothing by least square method - differentially for boys and girls; and delta between parameters of boys and girls; maximal quantitative level of growth changes in cm (IPHV), different for boys and girls as well, and delta between the parameters.

Results. The difference of APHV between boys and girls for each population under study is about two years - boys have delayed PHV as compared to girls in any ecological niche. Secular dynamics of APHV has nonlinear character, doesn’t decrease progressively through the whole historical interval from 1920th to 2000th, despite of permanent increase of the level of anthropogenic stress in cities under analysis, the lowest APHV is fixed in 1980th. Correlations of APHV with absolute annual H values through the age interval 6/7-17 years is systematic and high enough for boys (correlation about 0,5, determination coefficient about 0,25) and accidental for girls, being revealed for only one annual age group among 12 analyzed. Correlations of IPHV with absolute values of H are maximal at 7 years and minimal at 17 years, the level of correlations is less for girls as compared to boys.

Conclusion. PHV really marks the secular somatic dynamics along with H itself as genetic marker. Correlation of APHV with absolute annual levels of H through the interval 6/7-17 years is systematic and significant for boys and accidental for girls, which witness to genetic determination of growth tempo of boys. Correlation of IPHV with absolute values of H, having highest levels at 7 years, points to the fact that height at 7 years is a real trigger of PHV parameters.