bluuebunny/crossref_metadata_2025 huggingface dataset:
Simultaneous Intravitreal Steroid and Anti-VEGF Therapy for Monotherapy-Resistant Chronic Wet Age-Related Macular Degeneration
Authors: Warter Alexandra , Heinke Anna , Cavichini Melina , Galang Carlo Miguel B. , Kalaw Fritz Gerald P. , Bartsch Dirk-Uwe , Cheng Lingyun , Freeman William R.
Published: September 2024

Background and Objective

The purpose of this study was to analyze the safety and efficacy of combined intravitreal anti-vascular endothelial growth factor (anti-VEGF) and steroid therapeutic agents for resistant choroidal neovascularization (CNV). A retrospective observational clinical study was performed assessing anatomic and visual changes in a consecutive cohort of patients with refractory chronic wet age-related macular degeneration resistant to high-dose aflibercept therapy.

Patients and Methods

Twelve eyes of 12 patients with unresponsive CNV despite aggressive monthly anti-VEGF (4-mg aflibercept [mean: 43.75 ± SD23.08]) were included. Combination consisted of simultaneous administration of anti-VEGF and corticosteroids. Study measures evaluated visual acuity, central retinal thickness (CRT), and intraocular pressure.

Results

Paired tests revealed significant CRT reduction from the baseline at the 1-month (388.58 ± 89.31 versus 334.00 ± 92.88,
P
= 0.0117), 2-month (388.58 ± 89.31 versus 312.08 ± 75.61,
P
= 0.0185), and 3-month (388.53 ± 89.31 versus 304.56 ± 53.28,
P
= 0.046) visit. The Kaplan-Meier curve showed a median time of remission (no retinal fluid) of 70 days (95% CI 53, 147 days).

Conclusion

Combination treatment demonstrated clear anatomic improvement in eyes with anti-VEGF-resistant CNV.

[
Ophthalmic Surg Lasers Imaging Retina
2024;55:698–704.]
Retinal Gliovascular Proliferation Secondary to Retinoblastoma Treated With Radiotherapy
Authors: Istre-Wilz Hannah , Ebert Jared J. , Augsburger James J. , Di Nicola Maura , Correa Zelia M. , Williams Basil K.
Published: September 2024

Background and Objective

Retinal gliovascular proliferation (RGVP) is a benign lesion of the retina that can arise idiopathically or secondary to another disease entity. This study describes the clinical features, treatment, and outcomes of six patients with secondary RGVP associated with irradiated, regressed retinoblastoma, and distinguishes it from late local relapse of retinoblastoma.

Patients and Methods

In a retrospective review of available clinical records of 550 patients evaluated for retinoblastoma in a single ocular oncology practice between 1975 and 2022, seven eyes of six patients were identified as having secondary RGVP overlying a treated and regressed retinoblastoma. The clinical features, treatment, and outcomes are described.

Results

The median age at RGVP diagnosis was 20 years. All RGVPs were associated with a completely regressed retinoblastoma and in proximity to a calcific tumor residue or chorioretinal atrophy that remained after external beam radiotherapy (six eyes) or plaque brachytherapy (one eye). Lesions were measured between 2.8 to 12 mm in largest basal diameter and 1.3 to 4.4 mm in thickness and described as globular, raised areas with focal retinal telangiectasis often associated with overlying subretinal fluid or hemorrhage. Median time between initial retinoblastoma treatment and detection of RGVP was 20 years. Treatment was decided based on evidence of lesion growth and most often consisted of laser photocoagulation and intravitreal anti-VEGF injection. Through available follow-up of the treated lesions, all exhibited at least partial regression, while two untreated lesions remained stable, reassuring us against late local relapse of retinoblastoma.

Conclusions

Secondary RGVP develops occasionally in association with regressed previously irradiated retinoblastoma. This lesion must be distinguished from late local relapse of active retinoblastoma.

[
Ophthalmic Surg Lasers Imaging Retina
2024;55:714–720.]
“That was terrifying!”: When 2SLGBTQQ+ individuals and rural women experiencing intimate partner violence are stalked
Authors: Kurbatfinski Stefan , Nixon Kendra , Marshall Susanne , Novick Jason , McBride Dawn , Letourneau Nicole
Published: September 2024

Background

Stalking reflects a lesser-studied form of intimate partner violence (IPV; e.g., physical abuse) that may occur pre- and postseparation between two or more partners, incurring lifelong pervasive health impacts on those involved. Intersectionality theory elucidates how Two-Spirit, lesbian, gay, bisexual, trans, queer, questioning, intersex, and asexual (2SLGBTQQIA+) individuals' and rural women's identities are oppressed by society, thus subjecting them to unique IPV experiences. Therefore, this study aims to explore how stalking manifests among 2SLGBTQQIA+ individuals and women living rurally with lived experiences, both of which are underrepresented groups in current stalking literature.

Methods

We used secondary data from two IPV studies conducted among 2SLGBTQQ+ (no intersex or asexual participants) individuals and rural women (n = 29). We interviewed 2SLGBTQQ+ (n = 18) and rural women (n = 11) who resided in Alberta, Canada and experienced IPV via semi-structured, qualitative approaches. A thematic analysis was guided by intersectionality theory to analyze the data, applying inductive and semantic approaches.

Findings

Of the 29 participants, 15 were stalked by their abusive partners and 9 reported on the negative impacts of being stalked. Rural women and 2SLGBTQQ+ individuals were mainly stalked via physical forms of stalking and cyberstalking, respectively. We describe other forms of stalking and the ineffectiveness of legal systems in those seeking support for stalking. The impacts of stalking (e.g., hypervigilance) were so profound that the feeling of being stalked persisted, which we termed phantom stalking.

Significance

2SLGBTQQ+ individuals predominantly experienced stalking through technology and rural women experienced stalking in more public or physical forms, which stemmed from intersections with community and geographical factors, respectively. We posit the notion of “phantom stalking” and discuss and differentiate it from other psychiatric diagnoses. Additionally, we provide important recommendations related to legislation, education, safety, and research.
Does the high school external examination grades and the type of high school attended impact the academic performance of freshmen university students?
Authors: Adesina Olumide Sunday , Obokoh Lawarence O. , Salami Olajumoke Olayemi
Published: September 2024

There is a general conception that high school academic performance and the type of school a child attends would determine his/her academic success in the university. In this study, 135 freshmen engineering students were sampled at the Redeemer's University, Osun State, Nigeria. The study aimed to determine if the Unified Tertiary Matriculation Examination (UTME) and the type of school attended impact on academic performance of students in the first year at the university. The results showed that there is a significant relationship between UTME scores and the results of engineering freshmen; that is, students who attended private secondary schools performed somewhat better than students who went to public secondary schools. Also, statistical analyses showed that the type of secondary school attended has a significant relationship with UTME scores in favor of students who attended private secondary schools. This study recommends that the government of Nigeria should make public secondary school more appealing to students who cannot afford private secondary schools by putting measures in place to train and employ qualified teachers, and improve teaching and learning conditions. The study aligns with the Sustainable Development Goals (SDGs) 4, to ensure inclusive and equitable quality education for all and lifelong learning.
Delayed covering causes the accumulation of motile sperm, leading to overestimation of sperm concentration and motility with a Makler counting chamber
Authors: Yu Lin , Cheng Qing-Yuan , Jia Ye-Lin , Zheng Yan , Yang Ting-Ting , Wu Ying-Bi , Li Fu-Ping
Published: September 2024

According to the World Health Organization (WHO) manual, sperm concentration should be measured using an improved Neubauer hemocytometer, while sperm motility should be measured by manual assessment. However, in China, thousands of laboratories do not use the improved Neubauer hemocytometer or method; instead, the Makler counting chamber is one of the most widely used chambers. To study sources of error that could impact the measurement of the apparent concentration and motility of sperm using the Makler counting chamber and to verify its accuracy for clinical application, 67 semen samples from patients attending the Department of Andrology, West China Second University Hospital, Sichuan University (Chengdu, China) between 13 September 2023 and 27 September 2023, were included. Compared with applying the cover glass immediately, delaying the application of the cover glass for 5 s, 10 s, and 30 s resulted in average increases in the sperm concentration of 30.3%, 74.1%, and 107.5%, respectively (all P < 0.0001) and in the progressive motility (PR) of 17.7%, 30.8%, and 39.6%, respectively (all P < 0.0001). However, when the semen specimens were fixed with formaldehyde, a delay in the application of the cover glass for 5 s, 10 s, and 30 s resulted in an average increase in the sperm concentration of 6.7%, 10.8%, and 14.6%, respectively, compared with immediate application of the cover glass. The accumulation of motile sperm due to delays in the application of the cover glass is a significant source of error with the Makler counting chamber and should be avoided.
Obese boys penile length: is it micropenis or just Buried?
Authors: Emara Mohammed H. , El Shall Sarah I. , Elrifaey Shaymaa M.
Published: September 2024

Background

Obesity in childhood is an escalating public health crisis with profound implications, including potential impacts on penile development. This study aimed to measure penile size in obese children and adolescents to detect the presence of micropenis and buried penis.

Methods

An observational cross-sectional study was conducted on 680 obese boys (BMI >95th percentile) aged 9.4±3.22 years. Stretched penile length (SPL) was measured using a conventional method. Anthropometric measurements, laboratory tests, and penile length categorization (normal, micropenis, buried penis) were performed.

Results

Sixty percent of participants had normal penile length, while 9.12% were diagnosed with micropenis, and 30.88% had buried penis. SPL positively correlated with age, weight, height, and BMI but negatively with height and BMI Z-scores. No significant correlations were found between SPL and glycated hemoglobin or impaired glucose tolerance diagnosis. Dyslipidemia and impaired glucose metabolism were observed.

Conclusions and recommendations

A high prevalence of micropenis and buried penis among obese boys underscores the profound impact of childhood obesity on penile development. Early screening and management strategies are crucial to mitigate long-term consequences. Adopting a multidisciplinary approach, involving pediatric endocrinologists, urologists, and psychologists, ensures a holistic treatment addressing both physical and psychological aspects of the condition. Furthermore, individualized treatment plans should be developed, potentially incorporating hormonal therapy, surgical interventions, or a combination of both.
Aplastic Anemia with Thrombopoietin Gene Mutation Successfully Treated with Romiplostim Monotherapy
Authors: Hegde Niranjan Gurunath , Munirathnam Deenadayalan , Sivasankaran Meena , Thangadorai Ravikumar
Published: September 2024

Background:

Eltrombopag and romiplostim are thrombopoietin-receptor agonists (TPO-RA), which are approved globally for the treatment of immune thrombocytopenia. However, thrombopoietin (TPO) is not just a regulator of megakaryocyte expansion but is also a vital cytokine for hematopoietic stem cell maintenance, supporting all cell lines. While the role of eltrombopag has already been established in aplastic anemia (AA) and is recommended in guidelines, evidence regarding romiplostim in AA is gradually emerging. Here, we narrate the successful treatment of AA with romiplostim.

Clinical Description:

A 6-year-old girl born out of third-degree consanguineous marriage, presented with pancytopenia without hepatosplenomegaly nor lymphadenopathy.

Management and Outcome:

Bone marrow was hypocellular. Etiological workup for bone marrow failure syndrome was unremarkable, confirming primary AA. She received blood products and intravenous immunoglobulin. Clinical exome sequencing showed homozygous mutation of the TPO gene, following which a trial of romiplostim, a TPO-RA, was given. Her cell lines improved dramatically, so she was continued on romiplostim maintenance therapy. The child soon became transfusion free and is asymptomatic currently after 2½ years, since diagnosis.

Conclusion:

Romiplostim, a TPO-RA, can be a potential therapeutic option, as monotherapy, in children with AA associated with TPO loss-of-function mutation. The treatment seems to be promising as it is well tolerated and economical.
Adaptive-Duplex Relay Selection for Cooperative Non-Orthogonal Multiple Access Networks
Authors: Zhao Jing , He Xiang
Published: September 2024

To further improve the spectral efficiency of the cooperative non-orthogonal multiple access (NOMA) network with half-duplex (HD) relaying and avoid the zero diversity gain due to the imperfect self interference estimation at high signa-to-noise ratio (SNR) value with full-duplex (FD) relaying, this paper developed a novel two-stage relay selection for a two-user multi-relay cooperative NOMA systems with adaptive-duplex (AD) relaying which can switch opportunistically between HD and FD relaying modes. An adaptive duplex based on fixed power allocation factor relay selection (AD-FPA-RS) scheme for cooperative NOMA networks is proposed in this paper, the relay can switch the work mode to the FD or HD state adaptively according to the current channel state information and the result of decode at the relay. Futhermore, the exact outage probability for the proposed AD-FPA-RS scheme is obtained in closed-form expression. The simulation and numerical results show that the proposed AD-FPA-RS scheme not only outperforms the existing HD-FPARS and FD-FPA-RS schemes in terms of outage behavior significantly, but also can obtain full diversity gain without the floor outage performance at high SNR region.
Drugs used for pain management in gastrointestinal surgery and their implications
Authors: Shukla Ankit , Chaudhary Rajesh , Nayyar Nishant , Gupta Bhanu
Published: September 2024

Pain is the predominant symptom troubling patients. Pain management is one of the most important aspects in the management of surgical patients leading to early recovery from surgical procedures or in patients with chronic diseases or malignancy. Various groups of drugs are used for dealing with this; however, they have their own implications in the form of adverse effects and dependence. In this article, we review the concerns of different pain-relieving medicines used postoperatively in gastrointestinal surgery and for malignant and chronic diseases.
Rens Krijgsman: Early Chinese Manuscript Collections: Sayings, Memory, Verse, and Knowledge. Studies in the History of Chinese Texts
Authors: Van Auken Newell Ann
Published: September 2024

The book under review is a study of manuscript texts from Warring States and early imperial China (approximately the 5th to 2nd centuries BCE); its specific topic is “manuscript collections,” that is, “single manuscripts containing multiple (originally) distinct texts”. In this book, Rens Krijgsman explores what happened when multiple texts came to be combined on the same material carrier: How were texts selected, organized, and integrated into individual collections? What relationships obtained among these different texts? And how did collections affect reception, including interpretation and perceptions of genre? Cautious not to overstep the evidence, Krijgsman acknowledges that certain basic information about production and use of early manuscript collections is wanting: we do not (and cannot) know who collected the texts and produced the manuscripts, nor can we know who used collections. Wielding impressive command of the technical aspects of early manuscripts and of a broad range of texts, he seeks to extract as much information as possible through a careful yet comprehensive analysis of the material aspects of manuscript collections, their content, and their organization.
Introduction
Authors: Sernelj Téa
Published: September 2024

Social transformations in Sinic intellectual history reveal a complex interaction among evolving cultural, philosophical, and artistic ideas and socio-political shifts. The Sinic region, encompassing areas in East and Southeast Asia influenced by Chinese script and culture—particularly Confucianism and various forms of Chinese Buddhism—includes China, Taiwan, Hong Kong, Macau, parts of Japan, Korea, Vietnam, and other neighbouring countries. The term “Sinic”, originating from the Latin word for China, highlights the shared cultural and linguistic heritage across these regions. This history illustrates how shifts in intellectual thought have continually influenced and been shaped by changes in societal structures and governance. The present publication explores the intricate relationship between the individual and the state—a theme that resonates deeply through the annals of Asian thought. This relationship, characterized by an evolving dialogue between personal autonomy and state authority, serves as the backdrop to the discussions presented in this issue. Each paper contributes to a broader understanding of how individuals have negotiated their space within the structures imposed by state ideologies, influencing and reshaping them in turn.
Beyond the age of hegemony
Authors: Sachs Jeffrey
Published: September 2024

This paper delves into the origins of modern conflicts amidst the waning dominance of the Western world, particularly the United States. It argues that contemporary tensions stem from this power shift, driven by technological advances and economic convergence. Advocating for a transition to multipolarity and multilateralism, this paper emphasizes the drawbacks of the continued US quest for hegemony and the benefits of global cooperation. It envisions a future characterized by peace and shared development, underpinned by international collaboration and respect for diversity.
19. Yüzyıl Divan Şairlerinden Eşref Paşa'nın Divanında Bulunmayan Bazı Şiirleri
Authors: Tombak Süleyman Anıl
Published: September 2024

19. yüzyıl, Divan edebiyatını besleyen pınarların kuruduğu ve Türk edebiyatının yüzünü Batı’ya çevirdiği bir dönemdir. Bu yüzyılda şairler, zamanlarının sosyal ve siyasi değişimlerine duyarlı bir şekilde eserlerini şekillendirmiştir. Bu popülariteye karşın Divan edebiyatı geleneğini sürdürme gayretine sahip şairler de bulunmaktadır. Encümen-i Şu’arâ Meclisi üyelerinden olan Eşref Paşa da bu şairlerden biridir. Eşref Paşa, çeşitli devlet kademelerinde görev almış, divan sahibi bir şahsiyettir. Kaside ve mersiye yazmada başarılı olan şairin ekseriyetle sanatında dikkate değer bir orijinallik bulunmadığı da kaynaklarda geçmektedir. Divanını 1861 yılında kaleme alan Eşref Paşa, çalışmaya konu olan risaleyi 1888 yılında nazmetmiştir. Dolayısıyla şairin divanında, risaledeki şiirleri bulunmamaktadır. Çalışmada, risaledeki şiirlerin muhtevası, dil ve üslup özellikleri incelenmiş ve bu risaledeki şiirlerin Divan’daki şiirlerle örtüştüğü görülmüştür. Çalışmaya konu olan risalede bir kaside, bir mersiye, bir Arapça nakarat, iki de Farsça beyit bulunmaktadır. Şairlerin biyografilerinin tekmil bir hâle getirilebilmesi için onlara ait olan bütün şiirleri ortaya çıkarmak önemli bir husustur. Örneğin Eşref Paşa’nın Divan’ında Arapça ya da Farsça herhangi bir manzume bulunmamasına karşın bu risalede Arapça ve Farsça yazılmış şiir parçaları bulunmaktadır. Bu çalışmada Eşref Paşa’nın Divan’ında bulunmayan şiirler ortaya konulmuştur. Şiirler, T.C. Başbakanlık Osmanlı Arşivlerinde Ferik Eşref Paşa adına kayıtlı olan bir risalededir.
One Does (Not) Choose Their Enemies. Why Is America against All?
Authors: Babkina S. K.
Published: September 2024

Book review: America against All [Amerika protiv vsekh] (2023). Geopolitics, Statehood and Global Role of the USA: History and Modernity [Geopolitika, gosudarstvennost’ i global’naya rol’ SSHA: istoriya i sovremennost’]. Moscow: LLC “Commonwealth of Cultures” [OOO “Sodruzhestvo kul’tur”], 588 p.

What is America for Russia, the rest of the world and itself? This question is answered differently by historians, journalists, writers, diplomats, academic researchers, and incumbent politicians. Why has the United States – in recent years especially – pursued an exemplarily offensive foreign policy, as if directed “against everyone”? The authors of the book of the same name, “America Against All. Geopolitics, Statehood and the Global Role of the United States: History and Modernity” offer their answer to this question. The authors of the monograph analyze a significant body of literature on the U.S. geopolitical thought, reflect on the origins of American statehood, and seek to trace the formation of the so-called ‘‘American empire” and the spread of American hegemony from the late 19th century to the present day. In conclusion, the authors outline proposals for democratizing modern America. This book review is an attempt to critically analyze the assessments and recommendations of a large number of authors from the Diplomatic Academy, IMEMO RAS, MGIMO University, RUDN, and branch institutes of the Russian Academy of Sciences.
US Bipartisan Consensus on China: The Making and the Implementation
Authors: Zhuravleva V. Yu.
Published: September 2024

According to the most experts, there is a bipartisan consensus in the United States regarding China: both parties recognize that China poses an existential threat to the United States, its economy, socio-political structure and the role as a global leader. This core conceptual consent represents a clear contrast with the endless battles between Democrats and Republicans in the domestic political arena, blocking any legislative initiatives and the development of a unified sociopolitical agenda for the country. This rare unity has made many observers to claim the emergence of a new external enemy, in the face of which America will be able to overcome its identical crisis and to come back to national unity. The political elite also actively uses the image of the enemy, calling on the Nation for unity. This article is aimed to understand what lies behind political slogans and the bipartisan concept of confronting China. The study is based on the analysis of several sources that make it possible to judge the attitude towards China in the United States along party lines, specific to each level of the party-political system party platforms at the federal level, legislative initiatives at the state and city levels, public opinion polls at the level of the society. The research hypothesis is that Democrats and Republicans, who agree on the conceptual vision of the Chinese threat, offer different ways to counter it. The difference in methods of struggle stems from different ideological and value models that manifest themselves in the implementation of both the socioeconomic agenda within the country and foreign policy strategies in the international arena. The unity of the parties ends exactly by the developing of a conceptual framework for confrontation with the opponent. The implementation of specific steps of the anti-Chinese agenda at the state and city levels is taking place in accordance with the ideological and political guidelines of each party, and the public attitude towards the Chinese threat demonstrates a clear split along party lines. The conceptual positioning of a new external enemy instead of unification brought to the United States anti-Chinese hysteria among conservative politicians at the state level, which was realized in the adoption of discriminatory laws in Republican states against Chinese citizens and a new wave of anti-Chinese sentiment in society, manifested in outbreaks of violence against Asian minorities.
Effect of the Collaborative Model on Communication and Clinical Reasoning in DPT Students’ Clinical Experiences
Authors: Ingegneri Karina , Rafael Carmina , Jenkins Lisa
Published: September 2024

Introduction: The collaborative clinical experiences pair one physical therapist (PT) clinical instructor (CI) with one or more student(s) (Wolff-Burke et al, 2022).The collaborative model has been widely accepted among nursing and other healthcare professions. Benefits of the collaborative model include improved communication and clinical reasoning, enhanced teamwork, and reduced anxiety among students. Additionally, the collaborative model facilitates peer-to-peer learning and leadership. Despite the benefits, PT education has been slow to embrace this model. This study's purpose was to determine if the collaborative model is effective in helping students obtain the required performance ratings required by the university during their clinical experiences. Subjects included student placement records were reviewed to determine inclusion and exclusion based on participation in a collaborative experience between Spring 2022 and Spring 2023.

Methods: Clinical Performance Inventory (CPI) data was obtained and analyzed in communication and clinical reasoning. The professionalism and academic tracking systems were also reviewed to obtain student history related to communication and clinical reasoning (CR). Demographic information on gender and age was also included for comparison.

Results: Every student passed their clinical experience. Students scored higher than the expected threshold for their respective clinical experiences, with 76.3% over performing on communication and 85.5% on clinical reasoning. Female students scored higher than male students on communication and CR for the Integrated Clinical Experience (ICE). Students referred to the professionalism tracking system scored 3% lower on communication and 2% lower on CR compared to those who were not referred to the professional tracking system.

Discussion: The collaborative model appears to be an effective supervision model for clinical experiences. It may provide an effective way for students to develop their communication and clinical reasoning skills. Future studies should be designed to compare students’ performance and perceptions between those in traditional and collaborative models.
Fatty Menace: A case report of superior ophthalmic vein fat embolism due to autologous fat grafting
Authors: Wongwaisayawan Sirote , Jenjitranant Pinporn
Published: September 2024

Autologous fat grafting is among the many procedures used for facial rejuvenation and reconstruction, and its popularity has been increasing in Asia and worldwide. This procedure carries a risk of arterial or venous occlusion, which can lead to serious consequences. Venous embolism following autologous fat grafting is rarely reported. Here, we present a case of superior ophthalmic vein fat embolism and orbital compartment syndrome in a patient who underwent autologous fat grafting. Timely diagnosis, appropriate referral, and comprehensive multidisciplinary assessment are crucial for achieving favorable clinical outcomes.
Using Risk Factors for Disease to Predict Probability of Contracting a Disease in Young Adults: Application to a Machine Learning-based Product That Recommends Lifestyle Changes to Increase Health and Longevity
Authors: Agarwal Taruna , Agarwal Jai , Jain Hrithik , Leddo John , Agarwal Dev , Erasani Arjun , Malik Yousef , Dunnington Jackson , Iruvanti Adarsh , Jain Shaurya , Illapakurthy Avyan , Illapakurthy Arnav , Duffy Gabriela , Vasireddy Shirali , Jha Rishab , Gurbuz Deniz , Anurag Avishi , Renjith Vishal , Sabharwal Harman , Sajjad Aryan , Sajjad Arsal , Cherukuwada Dharana , Tewtia Abhinav , Shrivastava Dhruv , Natarajan Harini , Ramineni Ishwarya , Jain Sambhav , Tripathy Krish , Manikandan Mitra , Rangareddyvari Veda , Lamba Saanvi , Thumma Prardhana Joy , Miran Arian , O’Brien Collin , Dandemraju Rithvik , Biear Harrison , Mannepalli Siddharth , Park Ryan , Amiruddin Raiyan , Sajja Jahnavi , Yu Julie , Abdelwahab Kareem , Melanathuru Ashna , Chavarria Gabriel , Saboo Neil , Miran Ehaan , Namilae Ananth , Nasibdar Sophia
Published: September 2024

In previous papers, we have described My Youthspan, a software program that takes the latest scientific research in wellness and longevity and uses data science and machine learning to make personalized recommendations for people to live longer and be healthier. My Youthspan is targeted towards adults 40 and older, many of whom have legitimate concerns about the risk of contracting serious age-related diseases. Currently, we are developing a similar product for young adults, aged 18-40. While most young adults do not face serious diseases such as cancer or cardiovascular disease, the United States Centers for Disease Control reports that 54% of young adults have one or more chronic health conditions. While these chronic health conditions, such as obesity or high blood pressure, generally are not immediately life-threatening, they tend to be risk factors for more serious conditions later on such as stroke or heart disease. The goal of the present paper is to describe a methodology for quantifying these risk factors and then showing how they can be used in evaluating how lifestyle changes may reduce the risk in young adults of later contracting major age-related disease.
Research on the Development Path of Industrial Tourism in Quanzhou City
Authors: Huang Yuying , Pang Jing , Zhang Shiya , Lin Ketao , Ye Jie , Huang Zhifeng
Published: September 2024

The development of industrial tourism can not only promote industrial integration and enhance the added value of industrial industries, but also drive the development of related service industries, create more employment opportunities, and help local economic prosperity. Many enterprises in Quanzhou belong to the traditional manufacturing industry, so the development of industrial tourism demonstration bases can promote the transformation and upgrading of the traditional manufacturing industry and the full utilization of resources. At the same time, industrial tourism also contributes to the protection and inheritance of industrial heritage, promotes industrial civilization and enriches tourism content. The article evaluates industrial tourism in Quanzhou from the aspects of industrial tourism resources, tourism source market, and government support, and discusses the development of industrial tourism, product development, spatial layout of resources, and marketing of industrial products in Quanzhou, which provides a referable basis for Quanzhou to formulate the industrial heritage protection and development planning.
Technological Communication and Re-living the world of Disabled through Sanjay Leela Bhansali’s films
Authors: PRAKASH MANISH
Published: September 2024

This paper seeks to understand the challenges faced by disabled people and the struggle they go through in their life through the imaginary world of Sanjay Leela Bhansali’s films. In order to understand it deeply, this research work will try to peel all the layers ingrained in these films and the disabilities shown will be dealt in detail to show how the protagonists of the film communicate with the world within and the world outside. For a comprehensive analysis of the issue, filmmaker’s three major films like Khamoshi (1996) Black (2005) and Guzaarish (2010) have been taken into consideration as they make us believe in the world of disabled people and the difficulties, they face in their day-to-day life. The protagonists of the films have their own unique way to deal with their handicaps but the emotional quotient which is attached with these films make the internal conflict quite obvious. Although, there have been few films like Koshish (1972) in the past and Taare Zameen Par (2007) in the recent times which dealt with this issue, but due to the relevance of such issues in the imaginary world of Sanjay Leela Bhansali, they become significant and let us dwell in that world to know it better. Therefore, the paper will make an attempt in understanding the broader issue of dis-ability through the prism of the above mentioned films and situate its argument in the peripheral image of this highly debated issue.
An Exploratory Study on the Impact on Marketing Techniques and other factors in the growth of the Indian automotive industry
Authors: Aggarwal Arshia
Published: September 2024

The Indian automobile industry has traversed a huge space since India attained independence. Since 1991 there has been a tremendous change with respect to foreign direct investment in this industry. The result of this is that the industry has become competitive for domestic demand with respect to high level of quality at affordable price. This has resulted in increase in exports as well as the industry becoming an integral part of the global value chain.
Gender Economics: The Underrepresentation of Females in the Labor Force
Authors: Lim Soo Hyun
Published: September 2024

In this paper, I study female labor force participation and consider potential threats and obstacles women face that may inhibit their participation in the labor force. This ultimately serves as the culprit and driving force for the underrepresentation of females in the labor force. My project presents the numerous factors that cause lower female labor participation, the possible benefits of increasing it, and potential solutions to overcome this economic disparity. I will analyze statistics from the World Bank by creating infographics such as scatterplots. In addition, I conduct literature reviews which serve as my main source of information.
An In-depth Study on Nuclear Weapons and Their Role in Global Politics
Authors: Kataria Parnika
Published: September 2024

Nuclear weapons’ continued existence has led to rising concerns across the world. They have gained importance in global politics across time and space. The Cuban Missile Crisis, Nuclear Proliferation Treaty, and Nuclear Deterrence have indicated that nuclear weaponry will stay relevant with their continued existence and that G-7 countries must restrict their use to ensure a peaceful future. Recent events in the world have increased the danger of nuclear weapons; Concerted efforts have to be made by all countries to reach a peaceful solution. Nuclear weaponry should be buried forever if humanity is to progress and prosper.
ЗАБОРАВЉЕНИ КЊИЖЕВНИК СА ЈУГА СРБИЈЕ: ДИМИТРИЈЕ Н. АЛЕКСИЋ (1857-1889), НИШКИ И ЛЕСКОВАЧКИ ПРОТА
Authors:   Универзитет у Нишу, Филозофски факултет, Максимовић Горан
Published: September 2024

У огледу је приказа књижевна биографија и животни пут заборављеног књи- жевника са југа Србије, Димитрија Н. Алексића (Алексинац, 11. новембар 1857 – Лесковац, 19. децембар 1889). Исказао се као црквени писац, књи- жевник и уредник у осамдесетим годинама 19. вијека. У огледу су приказани радови поучно-вјерског карактера, приповијетке, пјесме и преводи са руског језика, као и уређивање Црквеног гласника (1887-1889), те календара Крин (1887). Посебно су представљене књиге овога писца: Богословија и свеш- тенство у Србији (црквена студија, Београд, 1880), Убрисана суза (поема, Београд, 1880), Велики четвртак (црквена поема, Београд, 1880), Велики пе- так (црквена поема, Београд, 1881), Велика субота (црквена поема, Београд, 1885), Мученици за веру (црквено-историјска новела, Београд, 1886), Свети Адријан и Наталија (црквено-историјска новела, Београд, 1888). Средишње аналитичко мјесто припало је роману Осветници (Ниш, 1886), као најком- плекснијем књижевном остварењу овога писца и једном од најранијих романа објављеног у некој од штампарија града Ниша.
ПРЕГЛЕД ДОСАДАШЊИХ ПРОУЧАВАЊА ГОВОРА ЛЕСКОВЦА И ОКОЛИНЕ
Authors:   Иновациони центар Универзитета у Нишу, Митић Анђела
Published: September 2024

Циљ овог рада је сумирање резултата истраживања која су до сада спроведена на материјалу лесковачког говора. Овај рад обухвата преглед литературе која се односи на лесковачки говор, почев од области синтаксе падежа, творбе, лексикологије, социолингвистике, методике наставе језика на дијалекатском подручју, ономастике, преко грађе организоване у речницима, до проучавања језика књижевних дела на дијалекту и представљања монографских истра- живања. До сада не постоји опсежна студија о говору града Лесковца. Дати преглед скреће пажњу на језичке области које су мање или више истражене на материјалу говора града Лесковца. Самим тим, видљива је неопходност темељнијих истраживања говора Лесковца и околине.
А КОД СИМЈАНЕ НЕШТО СЕ РОЂАЦИ ПРИБИРАЈУ2: ЕТНОГРАФСКИ СЛОЈ ДЕЛА АНЂЕЛКА КРСТИЋА
Authors:   Универзитет у Нишу, Филозофски факултет, Бојанић Ћирковић Мирјана
Published: September 2024

У односу на књижевнокритичке и књижевноисторијске прегледе где се доку- ментарна проза Анђелка Крстића смешта у прву фазу његовог стваралачког процеса и одређује као засебан жанр, овај рад се усмерава ка документарном поступку овог ствараоца, евидентном у целом књижевноуметничком опусу, и условљеном многим спољашњим чиниоцима мимо периодизацијског (со- цреалистичког) контекста. Нарочита пажња је посвећена етнографском слоју Крстићевог капиталног дела, романа Трајан, репрезентативног и у погледу начина трансмисије фолклорне грађе, и у погледу њене квантитативне за- ступљености. Унутар овог слоја, иманентно-поетички су истражена семан- тичка језгра Крстићевих дела – мотиви печалбарства и свадбе, без заобила- жења интеркултуралног аспекта Крстићевог стваралаштва, условљеног са- мим поднебљем на коме се развијао као писац, и које је описивао (Дримкол у данашњој Северној Македонији).
ИЗ ЂУРЂЕВДАНСКЕ ОБРЕДНО-ОБИЧАЈНЕ ПРАКСЕ СИРИНИЋКЕ ЖУПЕ
Authors:   Универзитет у Приштини са привременим седиштем у Косовској Митровици, Филозофски факултет, Дејановић Милица
Published: September 2024

Сиринићка жупа има богату обредно-обичајну праксу која још увек није довољно истражена.Ђурђевдан се сматра највећим пролећним празником чију прославу карактеришу бројне ритуалне радње.Наведеним радњама настоји се магијским путем обезбедити здравље људи, стоке, али и плодност усева.У овом раду представићемо и анализирати поједине компоненте које прате обредно-обичајну праксу Сиринићана
Debate sobre Forma e Conteúdo
Authors: Leão Martha
Published: September 2024

O presente trabalho se propõe a responder à crítica formulada sobre o argumento de que o tributo não restringiria direitos fundamentais. Do ponto de vista formal, o artigo estabelece os limites do debate científico, identificando falácias argumentativas da referida crítica para fixar os termos da presente resposta em níveis científicos, sem adentrar em qualificações de ordem pessoal, que nada agregam ao debate dogmático acerca do tema. Do ponto de vista material, o artigo aborda a posição da doutrina alemã sobre a relação entre tributo e direitos fundamentais; a correção da afirmação de que o tributo restringe direitos fundamentais, ainda que essa restrição possa, se exercida de acordo com a Constituição e a lei, ser legítima; a distinção entre normas de natureza fiscal e extrafiscal e as diferenças interpretativas decorrentes dessa distinção; e a correção desses argumentos frente ao conteúdo da Constituição de 1988.
Garantia contra a Mudança de Interpretação pela Administração Tributária
Authors: De Laurentiis Thais
Published: September 2024

Conhecendo as regras jurídicas basilares do controle das mudanças de orientação pela Administração Tributária, vale dizer, os arts. 100 e 146 do Código Tributário Nacional, propomos neste artigo efetuar um paralelo com a experiência estrangeira, especificamente apresentando como a questão é tratada pelo Direito francês. A análise se mostra pertinente em razão da influência que a França representa para a experiência brasileira em termos de direito público e, especialmente, Direito Administrativo, bem como pelo desenvolvimento francês, em nível de legislação e doutrinário, da “garantia contra mudança de critério jurídico pela Administração Tributária”.
Avanços e Controvérsias da Nova Lei do Cebas
Authors: Coelho Pasin João Bosco , Dallari Júnior Hélcio de Abreu , Teani Gatto Vanni Fernanda
Published: September 2024

O artigo se propõe a analisar os novos requisitos fixados pela Lei Complementar n. 187, de 16 de dezembro de 2021, em relação à certificação das entidades beneficentes e os procedimentos referentes à imunidade de contribuições à seguridade social. Para uma abordagem qualitativa, adota como metodologia a análise legislativa, doutrinária e jurisprudencial, tendo por escopo um estudo crítico acerca da evolução do assunto. Aborda as principais controvérsias jurídicas e procedimentais surgidas com a atual regulamentação, de modo a traçar temas que podem ser objeto de futuros questionamentos judiciais. Por fim, com amparo na legislação, além de precedentes similares em situações prévias e doutrina sobre o assunto, busca mencionar as possíveis soluções e consequências oriundas das controvérsias constatadas.
Tampon Tax
Authors: Miyake Alina
Published: September 2024

O objetivo do presente artigo é analisar a tributação sobre o consumo aplicável aos produtos menstruais no Brasil considerando a aplicação do princípio da seletividade, questões de igualdade de gênero, evasão escolar e saúde. Esse estudo pretende apresentar o problema da pobreza menstrual sob a perspectiva nacional, comparando as iniciativas locais de combate a essa questão social com as tendências internacionais sobre o tema. O estudo comparado contemplará, por um lado, a legislação de alguns países da África, Escócia, Estados Unidos, Nova Zelândia e Reino Unido e, por outro lado, as legislações federal (IPI e PIS/Cofins) e estadual (ICMS) sobre a matéria bem como os projetos de lei em discussão no Brasil.
Inconstitucionalidade do Prazo Estabelecido pela Receita Federal para Compensação de Crédito Judicial
Authors: Camargo Marinucci Sidnei
Published: September 2024

A compensação de créditos decorrentes de decisão judicial transitada em julgado está disposta na Instrução Normativa n. 2.055/2021, que dispõe sobre restituição, compensação, ressarcimento e reembolso, no âmbito da Secretaria Especial da Receita Federal do Brasil.Após deferida a habilitação do crédito judicial junto à Receita Federal, o sujeito passivo terá o prazo de 5 (cinco) anos para apresentar a declaração de compensação, nos termos do art. 106 da referida Instrução Normativa.Se o credor não utilizar o crédito habilitado dentro do prazo fixado pela norma administrativa, perderá seu direito creditório em relação ao saldo não utilizado, já que não se admite a restituição desse valor.O presente artigo pretende demonstrar que essa limitação temporal estabelecida pela Receita Federal do Brasil não tem fundamento legal, não podendo ser definido por meio de norma administrativa em razão do princípio da legalidade estrita aplicada no Direito Tributário.
Por um Princípio Jurídico-tributário da Cooperação
Authors: Goldschmidt Fabio Brun , Andrade Leonardo Aguirra de
Published: September 2024

O artigo apresenta os fundamentos para a construção e a aplicação de um novo princípio em matéria tributária no Brasil, o Princípio da Cooperação Tributária, a partir das normas e princípios já constantes do texto constitucional brasileiro.
Incidência de Imposto de Renda sobre Criptomoedas
Authors: Guimarães Bruno A. François , Sangalli Sandri Guilherme
Published: September 2024

É fato que as criptomoedas estão a caminho de se consolidar em um papel de destaque na ordem econômica mundial. Todavia, diante dos obstáculos à compreensão da natureza jurídica de um ativo tão inovador, são muitos os desafios no desenvolvimento de uma estrutura legislativa apropriada para regulamentá-las. A matéria encontra especial relevância no Direito Tributário, que com suas categorias estanques de hipótese de incidência, encontra dificuldades em regulamentar a tributação de um ativo dotado de características tão fluídas e complexas. Diante de tal cenário, o presente trabalho pretende contribuir com o estudo sobre a tributação das criptomoedas, especialmente quanto à incidência do Imposto de Renda sobre estes ativos.
Problema do Depósito em Ações Tributárias
Authors: Santiago Gonçalves Silva Gabriel
Published: September 2024

O artigo busca demonstrar, a partir do diálogo entre o Direito Tributário, o Direito Financeiro e o Direito Processual Tributário, que o dinheiro depositado judicialmente pelos contribuintes não pode ser considerado tributo pago. Inicialmente, será delimitado o que é o depósito realizado em ações tributárias. Em seguida, o artigo identificará as normas jurídicas que regem a utilização das verbas dos depósitos pelos entes federativos. Na sequência, será feita uma análise jurisprudencial crítica do conjunto de argumentos deduzidos em juízo pelo Fisco que fundamentam a negativa da substituição do depósito por outras garantias. Na análise, será feito um recorte temporal para identificar a reação judicial aos pedidos de substituição no contexto da crise sanitária acarretada pela covid-19.
Coisa Julgada em Matéria Tributária
Authors: De Sá Pittondo Deligne Maysa , Pinto Pereira da Rocha Diego Pabulo
Published: September 2024

O presente trabalho busca analisar brevemente a história do controle de constitucionalidade no Brasil e entender se as decisões do Supremo Tribunal Federal poderiam ou não cessar os efeitos da coisa julgada. Em seguida, buscou-se analisar o instituto da coisa julgada e as decisões proferidas pela Suprema Corte nos Temas de Repercussão Geral n. 881 e 885. A pesquisa se baseia na revisão doutrinária e análise jurisprudencial, sobretudo em relação aos institutos da súmula vinculante e repercussão geral. Verificou-se diferentes posições acerca do tema. Conclui-se que as decisões em controle concentrado possuem eficácia erga omnes, sendo capazes de cessar os efeitos da coisa julgada nas relações jurídicas de trato continuado. No controle difuso, verifica-se um desacerto do Supremo Tribunal Federal ao entender que as decisões em repercussão geral possuem eficácia erga omnes. Em ambos os casos, a Suprema Corte falhou em não modular os efeitos da decisão, na medida em que havia razões de segurança jurídica suficientes para que se procedesse dessa forma.
“Sumularização” do Direito Tributário Brasileiro
Authors: Koury Paulo Arthur Cavalcante
Published: September 2024

Este artigo visa examinar a hipótese de que a manipulação do escopo de precedentes por meio das “teses de julgamento”, em recursos repetitivos no STF e no STJ, bem como em processos de controle concentrado de constitucionalidade, no STF, especialmente em matéria tributária, representa violação à Constituição Federal de 1988. Para tanto, são inicialmente analisados dois exemplos de formação e aplicação das “teses de julgamento” por parte dos próprios Tribunais Superiores, que demonstram o seu tratamento como efetivos enunciados a partir dos quais são reconstruídas normas gerais e abstratas, cujo escopo é totalmente distinto dos casos levados à análise das respectivas cortes. Em seguida, demonstra-se que inexistem fundamentos infraconstitucionais que justifiquem essa maneira de fixação e aplicação das “teses de julgamento”, seja no Código de Processo Civil de 1973, seja no CPC em vigor. Ao final, conclui-se pela inconstitucionalidade desta maneira de formação e aplicação do regime de fixação de teses, por violação ao princípio da separação de poderes.