bluuebunny/crossref_metadata_2025 huggingface dataset:
Peran Pengetahuan dan Pengalaman Nasabah Bank Syariah Dalam Memajukan Perbankan Syariah
Authors: Sukardi Sukardi
Published: December 2022

Bank syariah merupakan bank yang operasionalnya mengikuti syariah agama Islam, bank syariah dikembangkan supaya menjadi mitra masyarakat menggunakan bank yang berkeadilan dan terhindar dari riba.  Tujuan penelitian ini adalah (1) menganalisis pengaruh pengalaman terkait bank syariah terhadap pengetahuan bank syariah dan (2) menganalisis pengaruh pengalaman terkait bank syariah terhadap niat menggunakan bank syariah, (3) menganalisis pengaruh pengetahuan terkait bank syariah terhadap niat menggunakan bank syariah. Populasi penelitian ini adalah mahasiswa   Fakultas Ekonomi dan Bisnis Universitas Ahmad Dahlan Yogyakarta, dengan sampel 133 responden, teknik mengambil sampel dengan stratified randem sampling dan teknik pengumpulan data dengan angket atau kuesioner. Kuesioner disebarkan dengan google form. Data dianalisis dengan regresi linier berganda dan hasil analisisnya adalah: (1) pengalaman terkait bank syariah tidak berpengaruh terhadap pengetahuan bank syariah, (2) pengalaman terkait bank syariah berpengaruh pada niat menggunakan bank syariah, (3) pengetahuan bank syariah berpengaruh pada niat menggunakan bank syariah.
Recognising the Embedded Child: Children’s Participation, Child Protection Inequities and Cultural Capital in Child Protection
Authors: Keddell Emily
Published: December 2022

Children’s right to participation in child protection decision-making is supported by moral imperatives and international conventions. The fragmented implementation of this right reflects an already-conflicted discursive terrain that attempts to incorporate both children’s agency and their need for protection. This article uses two key theoretical lenses to further examine this terrain: child welfare inequalities and cultural capital. These theories draw attention to how social inequities and cultural capital relating to culture and class affect how participation plays out. An unintended consequence of constructing children within a traditional liberal account of rights, within neoliberal and ‘child focussed’ policy paradigms, is the reduction of an acknowledgment of the culturally contested nature of an individualistic construction of children, excising children from their social backgrounds and promoting the notion of a ‘universal child’. With a particular focus on class, culture and professional paradigms, I argue that the ways children’s views are elicited, the content of those views and how they are interpreted, become subject to a set of professional assumptions that tend to take little cognisance of the social backround of children, including norms relating to class, ethinicity and the oppressive structural relations relating to those two factors. This process is shored up with concepts such as attachment theory, the ‘adultification’ of children of colour, the diminishing of Indigenous concepts of children and childhood, and the pre-eminence of the ‘concerted cultivation’ middle class parenting style. The child’s cultural worldview and manner of expressing it may clash with professional cultures that emphasise an ability for verbal expression, independence, and entitlement when negotiating preferences with representatives of powerful social institutions such as child protection systems. Many children may not comply with this expectation due to both cultural and class socialisation processes, and the histories of the oppressive functions of child protection systems. The unspoken power of child protection organisations that must engage in constant translation of children’s cultural capital to ensure participation, may instead better serve children’s participation aims by devolving authority to affected communities. Communities reflecting children’s own, may be better able to offer recognition to children and enable their participation more effectively.
Relação entre saúde mental e uso de substâncias psicoativas em escolares
Authors: Fogolin Fernandes Beatrice , Xander Russo Letícia , De Lucas Bondezan Kezia de Lucas
Published: December 2022

A adolescência é uma fase do desenvolvimento de grande exposição e vulnerabilidade a comportamentos de risco, como os relacionados às substâncias psicoativas. Devido ao elevado número de usuários e a experimentação precoce dessas substâncias, há um interesse crescente em identificar os fatores de risco e mecanismos subjacentes associados a esse comportamento. Nesse sentido, o presente artigo busca analisar a relação entre o estado de saúde mental e a experimentação e frequência do uso de drogas lícitas (álcool e tabaco) em escolares. Foram consideradas três variáveis de saúde mental: insônia, solidão e ausência de amigos. Com base nos dados da Pesquisa Nacional de Saúde do Escolar (PeNSE) de 2015, o modelo de regressão logit ordenado foi estimado. As características individuais, o contexto familiar e a região de residência foram incluídas no modelo como covariáveis. Observou-se uma menor probabilidade de nunca ter experimentado substâncias psicoativas, tanto álcool quanto cigarro, em escolares que se sentem sozinhos e apresentam dificuldades para dormir. Além disso, solidão e insônia foram relacionadas com maior frequência ao uso dessas substâncias. Tais resultados fornecem evidências da importância de integrar a saúde mental às políticas públicas e práticas educativas de prevenção e redução do uso de substâncias psicoativas na adolescência.
Module Development with Problem Based Learning (PBL) Model Based on Environmental Wetland to Increase Students’ Learning Outcomes
Authors: Aufa Mohamad Nor , Iriani Rilia , Saadi Parham , Hasbie Muhammad , Fitri Muhammad Awaluddin , Yunita Amalia
Published: December 2022

Research has been carried out on the development of modules with the Problem Based Learning (PBL) model based on wetland environments on the topic of acid-base solutions. This study aims to determine: the validity, practicality and effectiveness of module development. This study used a research & development design of a 4-D development model that was modified into 3-D, the data collection techniques used a test of student learning outcomes and a questionnaire. The research was conducted at SMAN 3 Banjarmasin with a sample of 10 students of class of XI PMIA 3 for small-scale trials, 24 students of XI PMIA 3 for limited-scale trials, and class of XI PMIA 1 and XI PMIA 2 with total 74 students for testing in a wide scale. Validity can be seen based on the results of the validation, the practicality of the students’ responses, and the effectiveness of the students' learning outcomes. The results showed that the module was considered valid with an average score of 146.4 and a percentage of 91.58% (very valid), practical with a percentage of 82.90% (good), effective with an average N-gain score of 0.84 (high), the average score of N-gain is 0.87 (high) for class of XI PMIA 1 and 0.86 (high) for class of XI PMIA 2. The results of this study indicate that the module with the Problem Based Learning (PBL) model based on the wetland environment on the topic of acid-base solutions is declared valid, practical and effective for use as a learning resource for students.

 
Biosorption of Fe (II) Ions from Aqueous Solution using Kepok Banana Peel (Musa acuminate)
Authors: Arifiyana Djamilah , Devianti Vika Ayu
Published: December 2022

The present study used adsorbents from Kepok banana peel to remove Fe (II) from an aqueous solution. The effect of adsorbent dose and initial metal concentration was investigated at room temperature to evaluate the maximum adsorption and adsorption capacity of Kepok banana peels. The adsorption parameters studied were adsorbent mass [0.5-2.5 g], and initial Fe (II) concentration [30-70 mg/L], where the operating conditions were 50 ml of Fe metal solution was added to each adsorbent, the pH value of the mixture was adjusted to 6. Then the mixture was stirred at 250 rpm for 30 minutes. In the adsorption process, it was found that 2.5 grams of mass adsorbent and 60 mg/L as initial metal concentration gave the highest adsorption and adsorption capacity, with 57.99% and 0.644 mg/g, respectively. FTIR spectra of adsorbent showed hydroxyl, carboxylic, and amine groups in Kepok banana peels. This study showed that Kepok banana peels had good potential for removing Fe (II) ions and could be used as a good adsorbent for removing the Fe (II) from water and wastewater at very little concentration.
Effectiveness of The Guided Inquiry-Based Flipped Classroom Learning System on Buffer Solution Materials on Students’ Learning Outcomes
Authors: Hartandi Megi , Mawardi Mawardi
Published: December 2022

This study aims to reveal the effectiveness of the Guided Inquiry-based Flipped Classroom learning System on the buffer solution material on student learning outcomes. This research was conducted with a non-equivalent control group design using a sample of 72 students divided into a control group and an experimental group. The instrument used in this study was a test of students learning outcomes in the form of a written test for student assessment. The test is carried out by giving pretest (Pretest) and posttest (Posttest) questions that have adjusted to the learning objectives. Based on the study's results, the N-Gain Value found in the experimental class was higher than in the control class, with values of 0.82 and 0.70 respectively. From the results of the t-test using the Microsoft Excel application, tcount is 2.47, and the ttable with a significance level of 0.05 is 1.99, so tcount  value is greater than ttablevalue. So can be concluded that using the flipped classroom learning system based on guided inquiry on buffer materials effective improves student learning outcomes
Analysis of the costs of feed production and fattening beef cattle using the example of a selected private farm
Authors:   Institute of Animal Science and Fisheries, Siedlce University of Natural Sciences and Humanities, B. Prusa 14, 08-110 Siedlce, Poland, Piszcz Hubert , Piotrowski Sławomir ,   Institute of Animal Science and Fisheries, Siedlce University of Natural Sciences and Humanities, B. Prusa 14, 08-110 Siedlce, Poland, Milczarek Anna ,   Institute of Animal Science and Fisheries, Siedlce University of Natural Sciences and Humanities, B. Prusa 14, 08-110 Siedlce, Poland
Published: December 2022

The paper analyses the costs of production of roughage and nutritive fodder and fattening HF and Limousine crossbreds of feeder cattle. The costs of growing fodder for feeder cattle were calculated per one hectare. The cost of producing one tonne of feed was determined based on the farm’s mean crop yield. The calculation included the cost of maintenance, including the cost of feeding 14 animals over 22 months. The animals were kept untethered in stalls with deep litter from the body weight of 36.86 kg to 812.14 kg on the selling date. The feeder cattle were fed according to the nutritional recommendations, and their feed rations were based on feedstock produced on the farm, except post-extraction meals and the mineral and vitamin mix Dolfos BO. It was demonstrated that the cost of producing one tonne of roughage ranged from PLN 66.98 (maize silage) to PLN 265.98 (hay), while that of grain oscillated from PLN 261.22 (rye) to approximately PLN 371 (oats and wheat). It was found that maize silage generated the highest cost in feeder cattle feeding. This fact should be associated with its largest share in feed rations, which as a result corresponded to nearly 5.5 tonnes per animal. As regards nutritive fodder, the highest cost was generated by nutritive fodder 2, which was also linked to its amount per animal. Throughout the fattening period, each animal consumed more than 10 tonnes of feed and its cost could be estimated at PLN 27,939.53. To sum up, the farm received PLN 1,616.75 of income from breeding one animal.
THE USE OF TiO2 TECHNOLOGIES IN ARCHITECTURE FOR AIR PURIFICATION IN THE CITY
Authors:   Necmettin Erbakan University in Konya, Turkey Faculty of Arts and Architecture, Meryem Alagöz , Pazdur-Czarnowska Anna ,   West Pomeranian University of Technology in Szczecin, Poland Faculty of Architecture, Department of History and Theory of Architecture
Published: December 2022

This paper explores the possibilities of the use of architectural design in benefiting the human condition in polluted cities and shows the role of art in shifting people's ideas about its influence on an urban wellbeing. The authors depict the possible usage of titanium dioxide (TiO2) technology as a component of building materials and its impact on clearing the atmosphere from nitrogen oxides. This research is focused on shaping the architectural form to promote light-active building materials for ecological thinking. The results of the academic research programme undertaken at WPUT (West Pomeranian University of Technology) in Szczecin, in cooperation with the Necmettin Erbakan University in Konya, are presented here.
ACCESSIBLE CITY – USING DIGITAL TECHNOLOGIES TO IMPROVE THE ACCESSIBILITY OF PUBLIC SPACE FOR PERSONS WITH SPECIFIC NEEDS
Authors:   Zachodniopomorski Uniwersytet Technologiczny w Szczecinie Wydział Architektury, Katedra Projektowania Architektonicznego, Zespół Symulatorium Dostępności, Krasowska Katarzyna , Zwoliński Adam ,   Zachodniopomorski Uniwersytet Technologiczny w Szczecinie Wydział Architektury, Katedra Urbanistyki i Planowania Przestrzennego, Zespół Symulatorium Dostępności
Published: December 2022

A city is accessible when everyone can easily live in it and use its resources. Persons with disabilities are the largest social minority in the world, and it is estimated that a sixth of the European Union’s citizens has a disability. This paper presents a review of current digital technologies that support persons with special needs in functioning in cities. The objective of the paper was to analyze existing digital tools that make city living easier to persons with various disfunctions and to formulate guidelines for the development of new tools that support making urban public spaces and services accessible.
FAKTOR PERSEPSI WISATAWAN DALAM KEPUTUSAN BERWISATA DI GLAMPING LAKESIDE RANCABALI, BANDUNG, JAWA BARAT
Authors: Kusumaningrum Dewi Ayu
Published: December 2022

Tourist needs related to lodging are very important to be considered by tourism producers. Convenience, complete facilities, optimal service and affordable prices are the keys to successfully meeting tourist needs. the reason for choosing accommodation is no longer just wanting to take a vacation. Another thing that is no less supportive to create a memorable vacation. One of them is by choosing the unique concept accommodation offered, which can be a special attraction that will make the trip unforgettable, such as the Glamping Tent which is a unique hotel in the form of large tents that function as rooms. For several years, the Glamping Lakeside tourism object has been operating, it has several problems including social impacts on the surrounding tourism business actors, promotions that do not reach the broad consumer market, limited accessibility and facilities. Apart from the problems faced, Glamping Lakeside Rancabali has become one of the favorite tourist attractions for tourists while on vacation in West Java. The formulation of the problem from this research are; How are Tourist Perceptions in Traveling Decisions at Glamping Lakeside Rancabali?. Descriptive quantitative research method with a questionnaire to collect data containing statements with a Likert Scale. The sampling technique is purposive sampling with the criteria of tourists who have traveled and choose Glamping Lakeside Rancabali tourism for the last 3 years. Descriptive statistical data analysis method; validity, reliability, mean and crosstab. The results showed that in general the mean tourist perception seen from environmental, personal, social and technological factors was positive. The results of the crosstab test of the respondent's profile with the questionnaire statement obtained that respondents with female gender answered agree more, the age of respondents aged 17-25 years mostly answered agree, high school education level most answered agree, profession students most agreed, income below Rp.2,000,000,-.Most of the respondents agreed with the statement of the questionnaire.
PRO ECOLOGY BEHAVIOR SISWA DITINJAU DARI KEPEMIMPINAN INSTRUKSIONAL (Di Madrasah Aliyah Negeri 6 Jakarta Timur)
Authors: Hanubun Mukhlisah Arif , Budiaman Budiaman
Published: December 2022

pro ecology behavior diartikan sebagai perilaku seseorang yang berkontribusi secara nyata dalam melindungi lingkungan dan seminimal mungkin merugikan lingkungan. Penelitian ini bertujuan untuk mengetahui hubungan antara locus of control, kepemimpinan instruksional terhadap pro ecology behavior siswa. Sampel dalam penelitian ini berjumlah 100 siswa pada Madrasah Aliyah Negeri 6 Jakarta. Metode yang digunakan dalam penelitian ini adalah metode survey yaitu dengan menyebarkan instrumen penelitian masing-masing variabel. Penelitian ini tergolong penelitian kuantitatif dengan menggunakan rancangan korelasional. Hipotesis diuji dengan menggunakan analisis statistik deskriptif. Deskripsi masing â€“ masing variabel disajikan dalam bentuk skor rata â€“ rata, nilai minimum, nilai maksimum, standar deviasi, varians dan distribusi frekuensi. Hasil penelitian menunjukkan bahwa terdapat hubungan positif antara kepemimpinan instruksional terhadap  pro ecology behavior siswa MAN 6 Jakarta Timur
Penerapan Konsep Green Building Pada Public Property Sebagai Upaya Menghadapi Climate Change
Authors: Rahman Muhammad Arif , Suwarna Iwan Permana
Published: December 2022

ABSTRACT

The concept of Green building is one of our efforts to maintain environmental and natural conditions so that they are not damaged and are in good condition. The building sector in Indonesia has a considerable contribution, especially in energy consumption, water consumption, land use, and several other problems that have the potential to have an impact on the environment, for this reason, it is necessary to apply a green building concept. Moreover, currently Indonesia is intensively improving infrastructure for the construction of public buildings. So it is hoped that the application of the green building concept to public property can be an effort to face climate change. This paper discusses the application of the concept of building to public property as an effort to face climate change. The study took a sample at the Jakarta International Stadium where with a literature review based on case studies with descriptive methods.

 

Keywords : Green building, Public property, Climate change, Jakarta International Stadium

 

ABSTRAK

 

Konsep Green building merupakan  sebagai salah satu upaya kita untuk menjaga kondisi lingkungan dan alam supaya tidak rusak dan berada di dalam kondisi yang baik. Sektor bangunan di indonesia memiliki kontribusi yang cukup besar terutama dalam konsumsi energi, konsumsi air, pemakaian lahan, dan beberapa masalah lainnya yang memiliki potensi  berdampak terhadap lingkungan, untuk itulah perlunya menerapkan suatu konsep bangunan hijau (green building). Terlebih saat ini Indonesia sedang gencar meningkatkan infrastruktur pembangunan bangunan umum. Sehingga harapannya penerapan konsep green building pada public property ini dapat menjadi upaya menghadapi climate change. Tulisan ini membahas tentang penerapan konsep building pada public property sebagai upaya menghadapi climate change. Penelitian mengambil sampel pada Jakarta International Stadium dimana dengan kajian literatur berdasarkan studi kasus dengan metode deskriptif.

Kata Kunci : Green building, Public property, Climate change, Jakarta International Stadium
Persepsi Ekologis Dan Ses Masyarakat Terhadap Penambangan Batu Alam Di Desa Mekarjaya Kecamatan Cigudeg Kabupaten Bogor Provinsi Jawa Barat
Authors: Rasminto
Published: December 2022

This study aims to analyze two things, namely: First, how is the sosial, economic and ecological perspective of the surrounding community towards natural stone mining activities; and Second, what factors influence the sosial, economic and ecological perspectives of surrounding communities on natural stone mining activities. This survey research was conducted in Mekarjaya Village, Cigudeg District, Bogor Regency, West Java Province with a population of 1,650 households. Samples totaling 67 respondents were taken randomly using the formula V = p (100-p)  Data collection techniques were done through a questionnaire and data analysis was performed using SPSS software Data analysis includes validity testing with the corrected item-total correlation technique, reliability test, Independent T test and structural equation modeling (SEM).

The results showed that although the general perception of the surrounding community on natural stone mining activities in Mekarjaya Village was quite good, partially it showed that sosial and ecological perceptions were classified as bad whereas for the economic perception the community was quite good.
Performance Evaluation of Nanocellulose-Engineered Robust Preformed Particle Gel upon Extrusion Through 1 to 1.5 mm Bead-Packed Porous Media
Authors: Wei Bing , Mao Runxue , Tian Qintao , Lei Wenhai , Lu Jun , Tang Jinyu
Published: December 2022

Preformed particle gel (PPG) holds promising potential for conformance control in fractured tight reservoirs as it enables mitigation of fracture channeling with insignificant leak off to matrix. However, conventional PPG is very susceptible to shrinkage, breakage, fatigue, and even degradation when extruding through narrow fractures due to its weak and brittle network. This hampers its development and application in the oilfields. This paper presents a comprehensive laboratory evaluation of a new kind of nanocellulose (NCF)-engineered robust particle gel (N-PPG) for this application. The results demonstrated that the presence of NCF noticeably improved the mechanical properties of N-PPG. The swelling kinetics and swelling ratio (SR) of N-PPG were almost independent of salinity. We packed porous media using millimeter-sized glass beads to replicate proppant-filled fractures after hydraulic fracturing. As anticipated, N-PPG exhibited a greater resistance factor (Fr) and residual resistance factor (Frr), and its plugging efficiency reached more than 99.3%. N-PPG was hardly broken even after extruding from pore-throat geometries with Dg/Dp up to 21.4, whereas the control PPG was notably ruptured at Dg/Dp = 14.7. Herein, this tough N-PPG could provide a solution to conformance control of fractured tight reservoirs.
Diversity of soil bacteria in alpine coal slag mountain grassland in different vegetation restoration years
Authors: Dao Ri-Na , Zhang Ying , Su Beibei , Ma xiong Lin , Tie long xiao , Lei Shengyan
Published: December 2022

1. Purpose:Our objective was to investigate changes in the bacterial diversity in the rhizosphere soil of slag mountains in different years of revegetation restoration.
2. Methods: The bacterial community was analyzed through high-throughput sequencing using the Illumina MiSeq platform. Seven soils were selected from different years of revegetation restoration in Qinghai, China. Statistical analyses revealed, the diversity of soil bacterial community was higher than that of other revegetation restoration soils that in 2017.
3. Results:The sequencing of 16S rRNA genes revealed that Proteobacteria and Actinobacteria were the dominant phyla at the phylum level. At the genus level, Sphingomonas was the dominant genus. Total nitrogen, available nitrogen, and total potassium influenced the horizontal community structure of the phylum, whereas total nitrogen, organic matter, and pH had a great influence on the horizontal phylum. The richness and diversity of the bacterial community in the soil that underwent revegetation restoration were greater in the third year (Y17) than in other years. In the seventh year of recovery, the richness and diversity of the bacterial community began to decline gradually.
4. Conclusion: The bacterial diversity of the coal mine slag mountain improved with the increase in vegetation restoration years.
Prospective flow cytometry analysis of leucocyte subsets in critically ill patients who develop sepsis: a pilot study
Authors: Layios Nathalie , Gosset Christian , Maes Nathalie , Delierneux Céline , Hego Alexandre , Huart Justine , Lecut Christelle , Damas Pierre , Oury Cécile , Gothot André
Published: December 2022

Purpose
Sepsis in critically ill patients with injury bears a high morbidity and mortality. Extensive phenotypic monitoring of leucocyte subsets in critically ill patients at ICU admission and during sepsis development is still scarce. The main objective of this study was to identify early changes in leukocyte phenotype which would correlate with later development of sepsis.
Methods
Patients who were admitted in a tertiary ICU for organ support after severe injury (elective cardiac surgery, trauma, necessity of prolonged ventilation or stroke) were sampled on admission (T1) and 48-72h later (T2) for phenotyping of leukocyte subsets by flow cytometry and cytokines measurements. Those who developed secondary sepsis or septic shock were sampled again on the day of sepsis diagnosis (Tx).
Results
Ninety-nine patients were included in the final analysis. Nineteen (19.2%) patients developed secondary sepsis or septic shock. They presented significantly higher absolute monocyte counts and CRP at T1 compared to non-septic patients (1030/µl versus 55/µl, p = 0.013 and 5.1mg/ml versus 2.5mg/ml, p = 0.046, respectively). They also presented elevated levels of monocytes with low expression of L-selectin (CD62Lnegmonocytes)(OR[95%CI]: 4.5 (1.4–14.5) p = 0.01) and higher SOFA score (p < 0.0001) at T1 and low mHLA-DR at T2 (OR[95%CI]: 0.003 (0.00-0.17) p = 0.049). Stepwise logistic regression analysis showed that both monocyte markers and high SOFA score (> 8) were independent predictors of nosocomial sepsis occurrence. No other leucocyte count or surface marker nor any cytokine measurement correlated with sepsis occurrence.
Conclusion
Monocyte counts and change of phenotype are predictive of secondary sepsis in critically ill patients with injury.
Population Divergence in the Mate Choice of Tribolium castaneum and Its Association with Gut Bacteria
Authors: Wang Zhengyan , Zhao Yaru , Wang Yang , Lu Yujie
Published: December 2022

To reveal population divergence in the mate choice and its mechanistic basis, the mating rhythm, mating preference and male volatile profiles of Tribolium castaneum (Herbst, 1797) (Coleoptera: Tenebrionidae) were studied. During ten days after emergence, six geographical populations of T. castaneum exhibited an identical daily or circadian mating rhythm. Males showed significant attraction to females while females did not show attraction to males. Furthermore, male attraction to females varied significantly within six populations, while female preference to males did not. Males from the HBWH population were most attractive to females sequentially followed by males from the populations of SHJD, HNZZ, GA1, GDST, and ZJJX, which was positively correlated with their 4,8-dimethyldecanal (DMD) production. Gnotobiotic reinoculation of two gut bacteria, Citrobacter freundii and Escherichia coli, to axenic males significantly enhanced their attraction to females and DMD production. It could be concluded that: (i) in the mate choice of T. castaneum, males were more like the sexual pheromone senders and females were the pheromone receivers; (ii) there was detectable divergence in the chemical communication among six populations of T. castaneum, which could be mainly attributed to alterations in the male pheromone production rather than changes in the female pheromone perception; and (iii) gut bacteria could modulate the chemical communication of the host by interfering with the pheromone production. Such knowledge will provide insights into optimizing trapping technologies for pest management.
Invasion history and distribution of the aquatic alien Elodea canadensis (Hydrocharitaceae) in Turkey
Authors: İkinci Nursel
Published: December 2022

Submerged macrophyteElodea canadensisMichx. is a non-native species to Turkey where it was first recorded in 1982. In this study, we aim to provide the current distribution ofE. canadensisin Turkey with notes on its invasion history and ecology. We performed field studies to measure the physical and chemical parameters of the invaded lakes. Our study is based on new field works, herbarium specimen examination and literature survey. As a result of our findings,E. canadensishas invaded 15 wetlands in eight water basins of Turkey. Eleven of the invaded wetlands, including the largest freshwater lake of Turkey have protection forms ranging from national parks, nature parks to nationally/locally protected areas. Type of the wetlands are also diverse, like drainage canals, ancient pools, karstic, crater, tectonic and alluvial set lakes with trophic status from oligotrophic to eutrophic. Physico-chemical parameters measured in seven invaded wetlands are as follow: Water temperature between 15.5–22.3°C, pH between 7.1–8.6, dissolved oxygen as 3.7–8,8 mg l-1, electrical conductivity as 230–610 µS cm-1, salinity between 0.1–0.29 ppt, and ammonium as 0.25–0.74 mg l-1. The altitude range of the colonized wetlands is between sea level and 2100 m a.s.l.Elodea canadensisforms single species stands in many sites, but we could totally record 22 accompanying macrophyte taxa in species rich habitats. Here we present the most comprehensive distribution and ecology data forE. canadensisin Turkey which could be used for further research and management to understand its future spread and effect on native vegetation.
A Case report: Development of Lyme arthritis despite 14 days of Amoxicillin for early Lyme disease
Authors: Schiever Noemie , Shahini Romina
Published: December 2022

Objective: The development of Lyme arthritis in children is usually preventable by the administration of appropriate antibiotic treatment. This case report reviews the case of a three-year-old child who developed Lyme arthritis despite beginning antibiotic treatment of amoxicillin a month after the onset of his symptoms.
Method: A review was done by grouping 5 cases that were similar in terms of delayed treatment with a bad outcome. The patients were analyzed based on their demography, symptomatology, clinical course, management, and results.
Results: Of the 5 cases reviewed, 3 were said to have delayed antibiotic treatment, leading to poor results. In two cases, children over 8 years of age were treated with doxycycline and those below the age of 8 with amoxicillin. Those who failed to respond for the second round of treatment were considered to have antibiotic refractory arthritis.
Conclusion: Early treatment of Lyme disease can prevent the development of Lyme arthritis. Earlier treatment within one month of symptom onset prompts a better outcome. Although rare, another factor that should be considered is antibiotic resistance.
Yunyao Qilongtian alleviates the progression of COPD by regulating HMGB1 and inhibiting AMPK/mTOR/ULK1 pathway induced mitophagy
Authors: Yang Chunyan , Liu Qing , Jing Haiqing , Zhang Juntu , Fang Chengbi , Zhu Youyang , Fu Yi
Published: December 2022

Background: Qilongtian is a traditional Chinese medicine compound with Yunnan medical characteristics. Its main components have the effect of inhibiting inflammation. Inflammatory response is closely related to the progression of Chronic obstructive pulmonary disease (COPD). Therefore, this study is mainly to confirm the influence and mechanism of Yunyao Qilongtian on pulmonary phlogosis and airway remodeling with COPD in patients.
Methods: In this study, using Wright Giemsa staining to measure the number of neutrophils in bronchoalveolar lavage fluid (BALF). Through ELISA assay, IL-β, IL-6 and TNF-α were detected in BALF. Expect that, we used HE staining to detect the Lung histological changes. Collagen deposition in or near the trachea was detected by Masson staining. Through Western blot assay, the proteins of the Mitochondrial autophagy and AMPK/mTOR/ULK1 signaling pathway were detected. The level of HMGB1, 8-OHdG and 4-HNE was detected by immunohistochemistry. Mitochondrial autophagy was detected by LC3 and MTR double immunostaining. Membrane potential was measured by JC-1staining. MitoSOX evaluates the production of mtROS. Cx I, II, III, and IV activity assay kit assay for the activity. ATP concentration was detected by ATP detection kit.
Results: Qilongtian significantly attenuated cigarette smoke (CS) -induced lung inflammation and airway remodeling, as well as the mitophagy and mitochondrial dysfunction of CS-induced. Qilongtian alleviated CS-induced HMGB1 upregulation. Overexpression of HMGB1 partially restored the protective effect of Qilongtian on lung inflammation and airway remodeling in COPD. As an inhibitor of the AMPK/mTOR/ULK1 pathway, AMPKi could partially restored the influence of OE-HMGB1.
Conclusion: Yunyao Qilongtian alleviates COPD lung inflammation and airway remodeling by inhibiting HMGB1 to inhibit excessive mitochondrial autophagy induced by AMPK/mTOR/ULK1 signaling pathway.
Awareness of head and neck cancers at a regional referral hospital in Tanzania
Authors: Abraham Zephania Saitabau , Mchele Kisula , Kahinga Aveline Aloyce
Published: December 2022

Background
Head and neck cancers (HNCs) are considered to be lethal and about 50% of the cases are diagnosed at advanced stages thus are associated with poor prognosis. Despite the high disease burden globally, there are scarce studies on awareness on HNCs and this is the first study in Tanzania to explore such awareness.
Methods
A hospital based cross sectional study was conducted at Geita Regional Referral Hospital from April to May 2022. Convenient sampling technique was utilized and data was collected using semi-structured questionnaires and analyzed using Statistical Package for Social Sciences (SPSS) version 23. P-value < 0.05 was considered to be statistically significant.
Results
More than half (54.9%) of the respondents considered themselves to be somewhat knowledgeable on head neck cancers. In the same study, 56.2% of the respondents didn’t know anatomical sites of head and neck cancers and over half (65.9%) of the respondents didn't know signs and symptoms of head and neck cancers. Cigarette smoking (73.7%) and alcohol consumption (65.1%) were the most correctly identified risk factors for HNCs. Regarding treatment options and preventive measures, 75.2% of the respondents knew cessation of cigarette smoking as a preventive measure for HNCs and surgery (91.7%) was the most known treatment option for head and neck cancers. Similarly, a significant association was found between knowledge on HNCs and some of the socio-demographic characteristics of the respondents.
Conclusion
Although majority of respondents considered themselves to be somewhat knowledgeable on HNCs, overall awareness on anatomic sites, clinical features, risk factors, preventive measures and curability of head and neck cancers at the Regional Referral Hospital seems minimal.
Analysis of characteristics of body composition of children and adolescents aged 3–17 years
Authors: Zhao Yan , Gong Jin-xin , Ji Yi-ting , Zhao Xiao-yun , He Lu , Cai Shi-zhong , Yan Xiang-ming
Published: December 2022

Background
We aimed to analyze the characteristics of the body composition of children and adolescents aged 3–17 in Suzhou, China.
Methods
A cross-sectional study between January 2020 and June 2022 using bioelectrical impedance was conducted to determine the fat mass (FM), fat-free mass (FFM), skeletal muscle mass, and protein and mineral contents of 24,845 children aged 3–17 who attended the Department of Child and Adolescent Healthcare, Children’s Hospital of Soochow University, China. Normally distributed data were expressed as mean ± SD, and groups were compared using the independent samples t-test.
Results
FM and fat-free mass increased with age in both boys and girls. The fat-free mass of girls aged 14–15 decreased after reaching a peak, and that of boys in the same age group was higher than that of the girls (p < 0.05). There were no significant differences in FM between boys and girls younger than 9 years old. The percentage body fat (PBF) and FM index of girls increased rapidly between 11 and 15 years of age (p < 0.05), and those of boys aged 11–14 were significantly lower (p < 0.05), suggesting that the increase in body mass index (BMI) was mainly contributed by muscle mass (MS) in boys.
Conclusions
The body composition of children and adolescents varies according to their age and sex. A misdiagnosis of obesity made on the basis of BMI alone can be avoided if BMI is used in combination with FM index, percentage of body fat, and other indexes.
A descriptive qualitative study exploring clinicians’ perspectives of the management of older trauma care in rural Australia
Authors: Ferrah Noha , Parker Catriona , Ibrahim Joseph , Gabbe Belinda , Cameron Peter
Published: December 2022

Background
For older trauma patients who sustain trauma in rural areas, the risk of adverse outcomes associated with advancing age, is compounded by the challenges encountered in rural healthcare such as geographic isolation, lack of resources, and accessibility. Little is known of the experience and challenges faced by rural clinicians who manage trauma in older adults. An understanding of stakeholders’ views is paramount to the effective development and implementation of a trauma system inclusive of rural communities. The aim of this descriptive qualitative study was to explore the perspectives of clinicians who provide care to older trauma patients in rural settings.
Method
We conducted semi-structured interviews of health professionals (medical doctors, nurses, paramedics, and allied health professionals) who provide care to older trauma patients in rural Queensland, Australia. A thematic analysis consisting of both inductive and deductive coding approaches, was used to identify and develop themes from interviews.
Results
Fifteen participants took part in the interviews. Three key themes were identified: enablers of trauma care, barriers, and changes to improve trauma care of older people. The resilience of rural residents, and breadth of experience of rural clinicians were strengths identified by participants. The perceived systemic lack of resources, both material and in the workforce, and fragmentation of the health system across the state were barriers to the provision of trauma care to older rural patients. Some changes proposed by participants included tailored education programs that would be taught in rural centres, a dedicated case coordinator for older trauma patients from rural areas, and a centralised system designed to streamline the management of older trauma patients coming from rural regions.
Conclusions
Rural clinicians are important stakeholders who should be included in discussions on adapting trauma guidelines in the rural setting. In this study, participants formulated pertinent and concrete recommendations that could improve trauma care in rural settings.
The Neurosurgical Outpatient Clinic: Comparison Between Accesses in Public and Private Activities
Authors: Menegatti Marta , Villano Nunzia Del , Scerrati Alba , Travaglini Francesco , Ricciardi Luca , Lofrese Giorgio , Cavallo Michele Alessandro , De Bonis Pasquale
Published: December 2022

Background: Neurosurgical clinic assesses presence and extent of pathologies of central and peripheral nervous system or disorders affecting the spine, to identify most effective treatment and possible recourse to surgery. Aim of this study is to evaluate the appropriateness of patients evaluation requests either in public or private neurosurgical clinics.
Materials and Methods: We collected and analyzed all the reports of outpatient visits of public and private clinic over a period between January and December 2018.
Results: There were 0.62% real urgent visits in the public sector and 1.19% in the private sector (p=0.05). Peripheral pathologies represented 12.53% and 6.21% of pathologies evaluated in public and private sector respectively (p<0.00001). In addition, 15.76% of visits in public lead to surgery, while they represented 11.45% in private (p=0.0003).
Conclusions: No study is available comparing accesses of patients in neurosurgical outpatient clinics. In public clinic, visits are booked as urgent on the prescription of the general practitioner: in reality, only 5% of these visits were really confirmed as urgent by the specialist. Peripheral pathologies are more frequent in public clinic, while cranial pathologies are more frequent in private one. Patients with cranial pathologies prefer to choose their surgeon by accessing private clinic.
Hole-type superconducting gatemon qubit based on Ge/Si core/shell nanowires
Authors: Lyu Zhaozheng , Zhuo Enna , Sun Xiaopei , Li Ang , Li Bing , Ji Zhongqing , Fan Jie , Bakkers Erik , Han Xiaodong , Song Xiaohui , Qu Fanming , Liu Guangtong , Shen Jie , Lu Li
Published: December 2022

We demonstrate that superconducting gatemon qubits based on superconductor-semiconductor-superconductor Josephson junctions can be constructed on hole-type Ge/Si core/shell nanowires. The frequency of the qubit can be set firstly by controlling the diffusion of Al in the nanowire via thermal annealing, which yields a roughly suitable critical supercurrent for the junction, and then by fine tuning of a gate voltage, by which an accurate adjustment of the frequency can be realized. On the resulted qubit, Rabi oscillation with an energy relaxation time T1~180 ns was observed in the time domain, and the gate voltage dependence of both T1 and the dephasing time T2 was investigated. Such a hole-type superconducting gatemon qubit, based on materials with strong spin-orbit coupling and the absence of hyperfine interaction, could be used for exploring the quantum coherence phenomena of hole-gas and potentially also Majorana physics in Ge-based quantum devices.
Severity of ATAD3A-related pontocerebellar hypoplasia correlates with the severity of pathogenic variants
Authors: Skopkova Martina , Stufkova Hana , Rambani Vibhuti , Stranecky Viktor , Brennerova Katarina , Kolnikova Miriam , Pietrzykova Michaela , Noskova Lenka , Tesarova Marketa , Hansikova Hana , Gasperikova Daniela
Published: December 2022

Background: Pathogenic variants in the ATAD3A gene lead to a heterogenous clinical picture and severity ranging from recessive neonatal-lethal pontocerebellar hypoplasia through milder dominant Harel-Yoon syndrome up to, again, neonatal-lethal but dominant cardiomyopathy. The genetic diagnostics of ATAD3A-related disorders is also challenging due to three paralogous genes in the ATAD3 locus, making it a difficult target for both sequencing and CNV analyses.
Results: Here we report four individuals from two families with compound heterozygous p.Leu77Val and exon 3–4 deletion in the ATAD3A gene. One of these patients was characterized as having combined OXPHOS deficiency based on decreased complex IV activities, decreased complex IV, I, and V holoenzyme content, as well as decreased levels of subunits of all complexes and decreased rate of mitochondrial proteosynthesis. All four reported patients shared a strikingly similar clinical picture to a previously reported patient with the p.Leu77Val variant in combination with a null allele. They presented with a less severe course of the disease and a longer lifespan than in the case of biallelic loss-of-function variants. This consistency of the phenotype in otherwise clinically heterogenous disorder led us to the hypothesis that the severity of the phenotype could depend on the severity of variant impact. To follow this rationale, we reviewed the published cases and sorted the recessive variants according to their impact predicted by their type and the severity of the disease in the patients.
Conclusion: The clinical picture and severity of ATAD3A-related disorders are dependent on the type of mutation and correlate with the predicted severity of the variants and their combinations. This knowledge can enable faster diagnosis and allow more accurate prognosis estimation, as well as a better understanding of the ATAD3A function.
Development of PSMA-PET-guided CT-based radiomic signature to predict biochemical recurrence after salvage radiotherapy
Authors: Spohn Simon KB , Schmidt-Hegemann Nina-Sophie , Ruf Juri , Mix Michael , Benndorf Matthias , Bamberg Fabian , Makowski Marcus R , Kirste Simon , Rühle Alexander , Nouvel Jerome , Sprave Tanja , Vogel Marco ME , Galitsnaya Polina , Gschwend Juergen E , Gratzke Christian , Stief Christian , Loeck Steffen , Zwanenburg Alex , Trapp Christian , Bernhardt Denise , Nekolla Stephan G , Li Minglun , Belka Claus , Combs Stephanie E , Eiber Matthias , Unterrainer Lena , Unterrainer Marcus , Bartenstein Peter , Grosu Anca L , Zamboglou Constantinos , Peeken Jan C
Published: December 2022

Purpose
To develop a CT-based radiomic signature to predict biochemical recurrence (BCR) in prostate cancer patients after sRT guided by positron-emission tomography targeting prostate-specific membrane antigen (PSMA-PET).
Material and Methods
Consecutive patients, who underwent 68Ga-PSMA11-PET/CT guided sRT from three high volume centers in Germany were included in this retrospective multicenter study. Patients had PET-positive local recurrences and were treated with intensity-modulated sRT. Radiomic features were extracted from volumes of interests on CT guided by focal PSMA PET uptakes. After pre-processing, clinical-, radiomics- and combined clinical-radiomics models were developed combining different feature reduction techniques and Cox proportional hazard models within a nested cross validation approach.
Results
Among 99 patients, median interval until BCR was The radiomic models outperformed clinical models and combined clinical-radiomics models for prediction of BCR with a C-index of 0.71 compared to 0.53 and 0.63 in the test sets, respectively. In contrast to the other models, the radiomic model achieved significantly improved patient stratification in Kaplan Meier analysis. The radiomic and clinical-radiomic model achieved a significantly better time-dependent net reclassification improvement index (0.392 and 0.762, respectively) compared to the clinical model. Decision curve analysis demonstrated a clinical net benefit for both models. Mean intensity was the most predictive radiomic feature.
Conclusion
This is the first study to develop a PSMA-PET-guided CT-based radiomic model to predict BCR after sRT. The radiomic models outperformed clinical models and might contribute to guide personalized treatment decisions.
Prevalence of chronic diseases among older adults in EAG and non-EAG states of India and its contextual determinants
Authors: Prasad Ravi Durga , Ghosh Koustav
Published: December 2022

Background: Although the rising burden of chronic diseases became a major challenge of public policy in India, especially in the ongoing COVID-19 pandemic crisis, there is a lack of awareness and access to healthcare resources and infrastructure in India. Therefore, the present study aims to assess the prevalence of chronic diseases among older adults in Empowered Action Group (EAG) and non-EAG states and their contextual factors.
Methods: The study used the Longitudinal Ageing Study in India (LASI), Wave-1 data, the survey was conducted during 2017-18. Bi-variate, spatial analyses, and logistic regression models have been carried out to assess the prevalence of chronic diseases among older adults.
Results: The prevalence of at least one chronic disease among older adults in India was about 55% and it was about 50% and 59% in EAG and non-EAG states respectively. The prevalence of hypertension (26%) was the leading chronic disease among older adults in India, followed by gastrointestinal problems (18%), arthritis (16%), diabetes (12%), and chronic lung diseases (6%). The odds of chronic diseases among urban older adults were 39% (Odds Ratio [OR]=1.39; 95% CI:1.29-1.50) and 30% (OR=1.30; 95% CI:1.24-1.35) higher than their rural counterparts in both EAG and non-EAG states respectively.
Conclusion: The study concludes that major contextual factors of chronic diseases were higher age, smoking and using smokeless tobacco, physical inactivity, never working, lack of education, Muslim religion, poor economic status, and residing in urban areas in both EAG and non-EAG states in India.