bluuebunny/crossref_metadata_2025 huggingface dataset:
Educación musical y desarrollo de la creatividad en escolares de 5 años en UGEL 02, Lima - 2023
Authors: Arteaga Robles Rocío Guillermina
Published: September 2024

El objetivo fue establecer de qué manera se relaciona la educación musical con el desarrollo de la creatividad en escolares de 5 años del nivel Inicial N° 386, UGEL 02, Lima - 2023. Método. Es de tipo básica, diseño observacional, enfoque cuantitativo y nivel relacional. El grupo muestral son 100 escolares a quienes los docentes evaluaron empleando fichas de observación de 10 y 14 ítems por cada uno de los instrumentos validados por expertos y aplicables. Los resultados descriptivos en el desarrollo de la educación musical el 80.80% de los niños y niñas son de regular y buena el aprendizaje musical, similar rección muestran en el interior de sus dimensiones. Los niveles de creatividad son 54.30% adecuados y 23.10% muy adecuados, en las dimensiones: de Fluidez el 41.70%, flexibilidad 54%, originalidad 55% y elaboración 63.30%. son adecuados. Conclusión: la educación musical se relaciona directa, positiva, moderada y significativamente con el desarrollo de la creatividad en escolares de 5 años del nivel Inicial IE N° 386, UGEL 02, Lima – 2023, según valores inferenciales de Rho (r = 0,950** y p = 0,000 < 0,05).
Calidad normativa y racionalidad administrativa en el sector energético europeo: a propósito de los procesos de concesión de autorizaciones de energías renovables
Authors: Canals Ametller Dolors
Published: September 2024

SUMARIO: 1. INTRODUCCIÓN: EXPECTATIVAS JURÍDICAS Y RIESGOS DEL DERECHO.— 2. CALIDAD NORMATIVA Y RACIONALIDAD ADMINISTRATIVA: INSTRUMENTOS CONOCIDOS Y SECTORIALMENTE INSUFICIENTES.— 3. MEDIDAS RECIENTES DEL DERECHO EUROPEO PARA RACIONALIZAR LOS PROCESOS DE CONCESIÓN DE AUTORIZACIONES DE ENERGÍAS RENOVABLES: 3.1. El fundamento: crisis climática, crisis energética y principio «primero, la eficiencia energética»; 3.2. La definición europea de «energía renovable» y de «proceso administrativo de concesión de autorización»; 3.3. La concurrencia de medidas normativas europeas ante la emergencia energética: 3.3.1. El régimen permanente con medidas estables a largo plazo; A.  La zonificación territorial de las energías renovables; B. Reglas y principios fundamentales del proceso administrativo de concesión de autorizaciones; C. La presunción legal refutable de interés público superior: rivalidad y priorización de intereses jurídicos presentes; D. Cooperación interadministrativa y suma de capacidades. 3.3.2. Las medidas urgentes y excepcionales para el período 2023 a 2025: A. El carácter temporal y adicional de las medidas de emergencia; B. Simplificación, proporcionalidad y racionalización de procedimientos administrativos; C. De nuevo, la presunción jurídica refutable; D. Mitigación de daños ambientales y medidas compensatorias; 3.3.4. Las medidas temporales que perduran hasta junio de 2025.
binomio agua y energía desde una perspectiva jurídica y económica
Authors: Molina Giménez Andrés
Published: September 2024

El presente trabajo se centra en el análisis del principio de recuperación de costes, y cómo éste influye en la financiación de las actividades relacionadas con la gestión del agua. Se analizan sus componentes esenciales y la jurisprudencia comunitaria que ha conformado su régimen jurídico. Con estas bases, se estudian las recientes ayudas otorgadas por el Gobierno de España para las demarcaciones del Segura y Júcar, que han subvencionado parcialmente la producción de agua de mar desalada y los costes de una relevante infraestructura de transferencia interna de recursos. La notable elevación de los costes energéticos venía impidiendo en la práctica la utilización de estos recursos en el sector agrícola.
Hidrógeno (renovable): la energía del agua
Authors: Mellado Ruiz Lorenzo
Published: September 2024

SUMARIO: 1. EL HIDRÓGENO RENOVABLE COMO EL VECTOR ENERGÉTICO DEL FUTURO.— 2. LA NECESIDAD DE UN MARCO EUROPEO REGULATORIO ADECUADO: ENTRE LA INTERVENCIÓN Y EL MERCADO: 2.1. Hacia la creación de un mercado interior sobre hidrógeno renovable; 2.2. La garantía de partida: ¿cuándo el hidrógeno renovable es «realmente» renovable? La funcionalidad del Reglamento Delegado (UE) 2023/1184, de 10 de febrero.— 3. LA SITUACIÓN A NIVEL INTERNO.— 4. BREVES CONCLUSIONES FINALES.
Gestión gerencial y calidad de servicios en la Municipalidad Distrital de Yacus, Perú, 2023
Authors: Quijano Zerpa Sally Jaqueline
Published: September 2024

Objetivo. Determinar la relación entre la gestión gerencial y la calidad de los servicios al usuario en la Municipalidad Distrital de Yacus, Huánuco (Perú), 2023. Métodos. El tipo de investigación fue básico y el diseño descriptivo correlacional. La población y muestra estuvo constituida por 24 funcionarios públicos. La técnica empleada fue la encuesta y como instrumento fueron utilizados un cuestionario para medir la variable de gestión gerencial y un cuestionario para medir la variable de la calidad de los servicios. Resultados. Se encontró una correlación positiva y moderada entre la gestión gerencial y la calidad de los servicios en la Municipalidad Distrital de Yacus, destacando coeficientes significativos de correlación (Spearman) para accesibilidad (0,927), eficiencia (0,871), equidad (0,703) y satisfacción general (0,703); todos con un nivel de significancia de 0,000. Conclusión. Basándonos en los resultados obtenidos, se concluye que en la Municipalidad Distrital de Yacus una gestión gerencial más eficiente está correlacionada positivamente con una mejor calidad de los servicios. Todos los resultados indican que mejorar la gestión gerencial puede llevar a mejoras sustanciales en estos aspectos clave de los servicios municipales
Каталитические стадии плазменной переработки отходов. 1. Углекислотный риформинг метана
Authors: Дюбанов Михаил Викторович , Артемов Арсений Валерьевич , Краснобаев Юрий Леонидович
Published: September 2024

В работе приведены результаты разработки комплекса плазменной переработки отходов с включением в технологическую схему каталитического углекислого риформинга, необходимого для выработки водорода. Обсуждаются преимущества предлагаемой технологической схемы. Проведён анализ эффективности существующих катализаторов углекислого риформинга: никелевых, кобальтовых, платиновых, карбидных, оксидных, сульфидных и др. Обсуждены кинетические закономерности и механизм углекислотной конверсии метана. Для реализации процесса предложен трубчатый реактор, конструктивно объединённый с газотурбинной установкой или плазменным блоком. Предложена также новая конструкция кольцевого плазменного реактора для проведения эндотермических каталитических реакций, в т. ч. и для углекислотного риформинга метана. Использование углекислотного риформинга метана позволяет проводить процесс совместного получения водорода и плазменной переработки отходов с реализацией замкнутого цикла по СО2, что кратно увеличивает экологическую привлекательность предлагаемой технологии.
Разработка новой конструкции жидкостного экстрактора колонного типа
Authors: Козин Юрий Васильевич , Беренгартен Михаил Георгиевич
Published: September 2024

При замене физически и морально изношенных существующих экстракторов, проектировании новых установок актуальна разработка усовершенствованных конструкций экстракторов с улучшенными технико-экономическими показателями. Был исследован массообменный процесс в разработанной новой конструкции жидкостного экстрактора колонного типа, сочетающем два типа контактных элементов — насадки и тарелки. В результате проведённых экспериментов выявлена интенсификация массообмена в слое насадки, но следует отметить, что при недостаточном количестве подачи экстрагента в слое насадки происходит обратное перемешивание, байпасирование сырья без контакта с экстрагентом. По этим причинам ухудшается качество рафината. При подаче экстрагента на тарелки качество рафината улучшается, отсутствуют продольные перемешивания. Более низкий расход экстрагента на тарелки позволит снизить расход энергоресурсов на регенерацию экстрагента. Интенсивным массообменом в секции насадки уменьшается диаметр экстрактора в данной секции, что снизит металлоёмкость при изготовлении аппарата. Полученные данные эксперимента можно также применить и при совершенствовании (реконструкции) существующих экстракторов в промышленности.
A halottakkal kapcsolatos eljárások
Authors: Katona Rita
Published: September 2024

The author provides an overview of the newly adopted regulations on corpse examination in Hungary.
In our 2014/4 issue, the last page of Rita Katona's article " Procedures for dead people " was unfortunately omitted. The article can be read in full in our 8/7/2014 issue at the following link: https://belugyiszemlejournal.org/index.php/belugyiszemle/article/view/1611
Az Europol-együttműködés tapasztalatai
Authors: Vetter Dániel
Published: September 2024

Aim: The aim of the article is to present the practical experience of cooperation between Europol, which plays a key role in international criminal cooperation, and Hungary.
Methodology: The author collected knowledge about the operation of Europol and its investigative support services by studying the available EU legislation, and by working as the Head of the Hungarian Liaison Bureau at Europol, as well as by carrying out the tasks of the former expert in the cyber-attacks priority and the deputy national EMPACT coordinator.
Findings: Europol’s system of cooperation with the Member States and operational and strategic partners provides the law enforcement agencies of the countries concerned with an opportunity that no other agency, institution or organisation can offer. In addition to supporting specific investigations, the institutional system also provides countries with IT, strategic and financial support.
Value: The article aims to provide a practical and comprehensive overview of the state of cooperation with Europol, to give a deeper insight into the day-to-day work of the law enforcement and judicial authorities and to provide the interested reader with contextualized insights into the steps and processes involved.
Pénzügyőrök az Europolban A Nemzeti Adó- és Vámhivatal, valamint jogelődje a Vám- és Pénzügyőrség részvétele az Európai Rendőrségi Hivatal munkájában
Authors: Bakai Kristóf Péter , Csatlós Zsolt
Published: September 2024

Aim: To give an overview of the cooperation between Europol and the National Tax and Customs Administration.
Methodology: The different areas of cooperation are presented by the authors based on the review of the available documents, the factual examination of the data and the experiences of conversations with liaison officers.
Findings: The National Tax and Customs Administration and its legal predecessor, the Hungarian Customs and Financial Guard, have been participating in the work of Europol since 2002. During this period, it was constantly present with liaison officers in joint tasks. NTCA’s financial officers and investigators try to make full use of the support provided by Europol, but at the same time, given the global nature of serious international and organised crime, it is necessary to constantly examine the further possibilities inherent in cooperation.
Value: The article adequately reviews and presents the relationship between the HCFG, later the NTCA and Europol, as well as the strategic and practical results resulting from it. During the interviews with the liaison officers, the authors got to know the practical aspects of the cooperation in depth and presented them in this article.
Europol 25, Magyarország 20
Authors: Hegyaljai Mátyás
Published: September 2024

Aim: Europol has evolved over the last quarter of a century, as its legal framework has changed in line with EU requirements, and its tasks have expanded and its network of contacts has become more extensive.
Methodology: Beyond the national offices of EU Member States, close cooperation is now possible across several continents through operational, strategic and working agreements with third countries.
Findings: The unique use of a liaison officer system and participation in joint investigation teams helps to build trust-based relationships. Over the years, several specialised crime centres have been set up.
Value: In Hungary, the design of the national unit has been developed in line with EU expectations and has adapted continuously over the last twenty years to the changes at Europol.
Europol cooperation in Hungarian law enforcement
Authors: Vas Zsolt , Szongoth Richárd
Published: September 2024

Aim: The aim of the article is to present the practical aspects of Europol’s role in Hungarian law enforcement.
Methodology: We have collected knowledge about the operation of Europol, its services and support of law enforcement by studying the available EU and Hungarian regulations, as well as performing the former management tasks of Europol Hungarian Liaison Bureau, and practical implementation of the tasks of the crime coordinator assisting domestic procedures.
Findings: Europol’s law enforcement services provide Hungarian law enforcement agencies with opportunities that cannot be provided by other agencies. In addition to supporting specific investigations, the institutional system also provides IT, strategic and financial support to countries.
Value: The study provides operational, practical insights into the possibilities of cooperation with Europol, which will allow the staff of the criminal and judicial authorities to have a deeper insight into the more effective detection and investigation, as well as answers on the individual services and their future, also interpreted in the context of the readers.
Experience of the Europol cooperation
Authors: Vetter Dániel
Published: September 2024

Aim: The aim of the article is to present the practical experience of cooperation between Europol, which plays a key role in international criminal cooperation, and Hungary.
Methodology: The author collected knowledge about the operation of Europol and its investigative support services by studying the available EU legislation, and by working as the Head of the Hungarian Liaison Bureau at Europol, as well as by carrying out the tasks of the former expert in the cyber-attacks priority and the deputy national EMPACT coordinator.
Findings: Europol’s system of cooperation with the Member States and operational and strategic partners provides the law enforcement agencies of the countries concerned with an opportunity that no other agency, institution or organisation can offer. In addition to supporting specific investigations, the institutional system also provides countries with IT, strategic and financial support.
Value: The article aims to provide a practical and comprehensive overview of the state of cooperation with Europol, to give a deeper insight into the day-to-day work of the law enforcement and judicial authorities and to provide the interested reader with contextualised insights into the steps and processes involved.
Europol’s role in the fight against cybercrime
Authors: Szabó Csaba
Published: September 2024

Aim: The aim of the study is to present the role and activities of Europol’s European Cybercrime Centre (EC3) in combating cybercrime, with a particular focus on the latest technological solutions and cooperation mechanisms.
Methodology: The research involved analysing the strategies and tools employed by the EC3. Data collection and analysis utilised Europol’s internal reports, publicly available sources, and case studies to provide a comprehensive overview of EC3’s activities and effectiveness.
Findings: The EC3 plays a crucial role in the fight against cybercrime, particularly in dealing with transnational criminal organisations and advanced cyber threats. The EC3 is divided into three main divisions: the operational unit, the digital support unit, and the expertise unit. The operational unit maintains four permanent analytical projects, each focusing on different areas of cybercrime.
Value: The study provides valuable insights into the functioning of the EC3 and its contributions to the global fight against cybercrime. It highlights Europol’s effective cooperation model, which aids in international collaboration against cyber threats. EC3’s activities significantly enhance information sharing and operational cooperation among member states, thereby increasing the effectiveness of defences against cybercrime.
The big law enforcement information exchange challenge
Authors: Ujfalussy Nikolett
Published: September 2024

Aim: The paper attempts to take stock and present the most significant dilemmas and challenges of cross border criminal data and intelligence exchange between law enforcement authorities of EU Member States that can be experienced by police personnel in the field at the moment.
Methodology: In addition to the relevant legislation, recommendations and best practices, the paper – based on personal experience as a police professional, supplemented by insights of the members of the EU law enforcement community – describes and illustrates the various challenges of today’s international police cooperation landscape.
Findings: The EU law enforcement information exchange scene is in the midst of its transformation due to globalisation and the progressive information and communication technology advancement. The evolution of the institutionalised cross border criminal data and intelligence exchange has to keep up with the world of crime and reflect the challenges which arise from the sensitive nature of the policy area itself, where any substantial development can only be reached by innovation and capacity building of the law enforcement sector.
Value: This snapshot is to give a structured overview and to draw more attention to the complexity and the controversies of the international law enforcement information exchange landscape, which policy-makers and police professionals have to face nowadays in order to successfully prevent, detect or investigate cross border criminal offences.
Financial guards at Europol. Participation of the National Tax and Customs Administration and its predecessor, the Hungarian Customs and Finance Guard in the workof the European Union Agencyfor Law Enforcement Cooperation
Authors: Bakai Kristóf Péter , Csatlós Zsolt
Published: September 2024

Aim: To give an overview of the cooperation between Europol and the National Tax and Customs Administration.
Methodology: The different areas of cooperation are presented by the authors based on the review of the available documents, the factual examination of the data and the experiences of conversations with liaison officers.
Findings: The National Tax and Customs Administration and its legal predecessor, the Hungarian Customs and Financial Guard, have been participating in the work of Europol since 2002. During this period, it was constantly present with liaison officers in joint tasks. NTCA’s financial officers and investigators try to make full use of the support provided by Europol, but at the same time, given the global nature of serious international and organised crime, it is necessary to constantly examine the further possibilities inherent in cooperation.
Value: The article adequately reviews and presents the relationship between the HCFG, later the NTCA and Europol, as well as the strategic and practical results resulting from it. During the interviews with the liaison officers, the authors got to know the practical aspects of the cooperation in depth and presented them in this article.
Scottish Gaelic
bithidh
, Manx
bee
, Irish
bíonn
: a synchronic and diachronic anatomy of the 3 sg consuetudinal present/future tense in pan-Gaelic
Authors: HUGHES A. J.
Published: September 2024

To date, there is no linguistic map or table available that provides us with a microscopic comparative distribution of the independent form of the present indicative for the pan-Gaelic area as a whole. Quite a few such detailed tables exist for Gaelic Scotland (§5) but none for Gaelic Ireland. In addition to providing a synchronic distribution of
bíonn
‘is wont to be’ for most dialects in Ireland (Appendix 1),
bithidh
‘will be’ in Scotland, and
bee/vees
in Manx, this article further seeks to analyse on a diachronic level the evidence provided for these particular verbal forms by two of the most significantly detailed comparative monuments to Gaelic linguistic heritage: (1) Heinrich Wagner’s
Linguistic atlas
; (2) Cathair Ó Dochartaigh’s
Survey of the Gaelic dialects of Scotland
.

1
Sworn to be free
: Escapes from Irish prisons during the War of Independence
Authors: RODDY CONOR
Published: September 2024

This article will place escapes during the War of Independence into the context of both the revolution as a whole and the specific context of political imprisonment. It examines the reasons the IRA engaged in escapes and how they sought to effect them. It also investigates the impact escapes had on prison staff, how the actions of staff influenced the outcome of an escape attempt, and how escapes affected the staff–management relationship within the prison service. Escapes provided numerous benefits for the IRA and the nationalist cause, ranging from material to symbolic benefits, and they were often successful thanks to various facilitating factors. For prison staff, escapes built on the demoralising effect the presence of political prisoners generally had: they increased tensions and provoked confrontations within the prison service; exposed serious deficiencies in the ability of some staff; and exhibited the impossibility of enforcing safe and secure custody in the ameliorated and highly charged atmosphere of Irish prisons. This is the first research that analyses escapes during the War of Independence collectively, and establishes that escapes were more than simply another IRA operation and another failing of Dublin Castle’s response to the nationalist movement. Instead, escapes reflect broader themes and factors that overshadow the Irish revolution in general.
An at-home and electro-free COVID-19 rapid test based on colorimetric RT-LAMP
Authors: Tran Diem Hong , Tran Hau Thi , Pham Trang Nguyen Minh , Bui Le Minh , Phung Huong Thi Thu
Published: September 2024

Introduction: In the fight against virus-caused pandemics like COVID-19, diagnostic tests based on RT-qPCR are essential, but they are sometimes limited by their dependence on expensive, specialized equipment and skilled personnel. Consequently, an alternative nucleic acid detection technique that overcomes these restrictions, called loop-mediated isothermal amplification following reverse transcription (RT-LAMP), has been broadly investigated. Nevertheless, the developed RT-LAMP assays for SARS-CoV-2 detection still require laboratory devices and electrical power, limiting their widespread use as rapid home tests. This work developed a flexible RT-LAMP assay that gets beyond the drawbacks of the available isothermal LAMP-based SARS-CoV-2 detection, establishing a simple and effective at-home diagnostic tool for COVID-19.
Methodology: A multiplex direct RT-LAMP assay, modified from the previously developed test was applied to simultaneously identify the two genes of SARS-CoV-2. We used a colorimetric readout, lyophilized reagents, and benchmarked an electro-free and micropipette-free method that enables sensitive and specific detection of SARS-CoV-2 in home settings.
Results: Forty-one nasopharyngeal swab samples were tested using the developed home-testing RT-LAMP (HT-LAMP) assay, showing 100% agreement with the RT-qPCR results.
Conclusions: This is the first electrically independent RT-LAMP assay successfully developed for SARS-CoV-2 detection in a home setting. Our HT-LAMP assay is thus an important development for diagnosing COVID-19 or any other infectious pandemic on a population scale.
Leptospirosis and melioidosis coinfection presenting as acute respiratory distress syndrome and osteomyelitis: Case report and systematic review
Authors: Panigrahi Manoj Kumar , Bal Shakti Kumar , Tripathy Tara Prasad , Moorthy Akshaya , Mohanty Swadesh Kumar , Mahapatra Ashoka , Bhuniya Sourin
Published: September 2024

Introduction: Leptospirosis and melioidosis are common in tropical and temperate climates and can be acquired by exposure to contaminated water and soil. However, concomitant leptospirosis and melioidosis infection is rarely described in the literature. We report a case of leptospirosis-melioidosis coinfection and systematically review the literature.
Case presentation: A 42-year-old male presented with fever associated with chills and rigor, dull aching pain in the right thigh, myalgia, progressive breathlessness, and dry cough for 10 days. At presentation, he was tachypneic and had tachycardia, and oxygen saturation was 46% in room air. Chest radiography and computed tomography scan showed interstitial involvement. Magnetic resonance imaging for thigh pain revealed right femur osteomyelitis. Leptospira serology was positive, and blood culture grew Burkholderia pseudomallei, confirming the diagnosis of melioidosis. Thus, a diagnosis of presumptive leptospirosis based on modified Faine’s criteria and systemic melioidosis was made. He received doxycycline and intravenous meropenem and improved.
Results: We performed a systematic review to understand the spectrum of leptospirosis-melioidosis coinfection. We identified only nine cases of coinfection described in literature. Only one patient had septic arthritis, and our case is the only one presenting with osteomyelitis. Serology diagnosed leptospirosis, whereas melioidosis was confirmed by blood culture in most patients. The majority of coinfected patients developed some complications, and six died.
Conclusions: Leptospirosis-melioidosis coinfection is rarely reported in the literature. Physicians should maintain a high index suspicion of leptospirosis-melioidosis coinfection in patients presenting with acute febrile illness following exposure to soil or freshwater, particularly in tropical and endemic regions.
Metagenomic next-generation sequencing assisted in the successful treatment of pneumonia caused by Talaromyces marneffei in an immunocompetent patient
Authors: Ye Ling-Yan , Zhao Xu-Ling , Qin Jia-Jia , Lin Jian
Published: September 2024

Introduction: Talaromyces marneffei (T. marneffei), a kind of endemic opportunistic pathogen, was previously thought to occur in HIV-positive individuals and non-HIV hosts with impaired immune function. However, the infection of T. marneffei in patient with normal immune function was rarely reported.
Case Presentation: We report a case of severe pneumonia caused by T. marneffei in an immunocompetent and HIV-negative patient, which was rapidly confirmed by metagenomics next-generation sequencing (mNGS) and treated successfully. The patient was a previously healthy 63-year-old male, who was admitted to hospital with fever for 11 days, cough and sputum for 1 week, and chest distress for 4 days. The infection of T. marneffei was quickly determined by alveolar lavage under bedside bronchoscope and mNGS test.
Results: Patient’s condition improved rapidly after voriconazole treatment, and he was evaluated as a HIV-negative case of T. marneffei infection with normal immune function. This is a sporadic case of T. marneffei in non-endemic areas, and mNGS played a very important role in the treatment of the disease. The patient’s immune function was relatively normal which was rare in clinical practice.
An alternative colorimetric RT-LAMP assay for the rapid detection of SARS-CoV-2: development and validation in Thailand
Authors: Klayut Wiphat , Wongchai Thanee , Chuenchom Nattagarn , Bhakdeenuan Payu , Bunchoo Supranee , Srisungngam Sopa , Suphankong Sirilada , Phetsuksiri Benjawan , Uppapong Ballang , Rudeeaneksin Janisara
Published: September 2024

Introduction: COVID-19, an emerging infectious disease caused by SARS-CoV-2, continues to be a global public health threat. The development of a colorimetric reverse transcription loop-mediated isothermal amplification (RT-LAMP) can extend the availability of simple, reliable molecular tests for the rapid detection of COVID-19.
Methodology: The RT-LAMP assay was developed using a new primer set targeting a portion of SARS-CoV-2 orf8. The method was validated at 63 ºC for 60 minutes with naked-eye visualization of the color change. The clinical performance was compared to a real-time reverse transcription-polymerase chain reaction (rtRT-PCR) using 273 RNA samples extracted from nasopharyngeal swab specimens.
Results: The developed RT-LAMP was specific to SARS-CoV-2 with a limit of detection at 15 RNA copies per reaction. The assay demonstrated diagnostic accuracy, sensitivity, specificity, positive predictive value, and negative predictive value of 90.48% (95% CI: 86.36–93.68%), 87.00% (95% CI: 81.53–91.33%), 100% (95% CI: 95.07–100%), 100% (95% CI: not available), and 73.74% (95% CI: 66.22–80.07%), respectively, compared to the rtRT-PCR. The greatest sensitivity of 98.03% (95% CI: 94.34–99.59%) was demonstrated in samples with the cycle threshold (Ct) values < 30 cycles.
Conclusions: The RT-LAMP method in this study showed good performance. The assay can increase the scope of laboratory testing for rapidly detecting SARS-CoV-2 in Thailand. Due to a decrease in COVID-19 cases, its application is beneficial when commercial alternatives are unavailable.
War from the Margins: Metalepsis and Metonymy in Pat Barker’s Toby’s Room and Sarah Waters’s The Night Watch
Authors: Marcellin Katia
Published: September 2024

Dans leurs romans de guerre historiques, Toby’s Room et The Night Watch, Pat Barker et Sarah Waters posent la question de la fidélité de la représentation. Cet article entend montrer comment, par le biais de la métalepse et de la métonymie, les deux écrivaines proposent une appréhension de la guerre fondée sur l’expérience des destructions qu’elle entraîne plutôt que sur la conformité aux faits historiques. Barker et Waters interrogent ainsi nos perceptions et nos représentations de ce qui, dans un événement individuel, collectif ou historique, mérite d’être mis en lumière, et nous font percevoir les processus d’invisibilisation qui sont le corolaire de ces « coups de projecteur ». Leurs récits sont relatés depuis des points de vue marginaux, mettant ainsi en évidence la façon dont certaines vies sont disqualifiées, perçues comme indignes ou « ungrievable » (Butler 2004). La métalepse et la métonymie deviennent des moyens de repenser le pouvoir politique de la représentation et de proposer des récits des et depuis les marges, qui tentent de réhabiliter les histoires oubliées des guerres .
ESG and risk
Authors: De Araujo Moxotó Ana Claudia , Dos Santos Pâmela Maria Lima
Published: September 2024

L’article propose un modèle opérationnel de reporting interne pour les entreprises agroalimentaires, à partir d’une revue institutionnelle. Les chiffres sur la malnutrition en France et dans le monde, le surpoids et l’obésité, le développement des MNT (maladies non transmissibles) ne cessent de croître, représentant des coûts directs et indirects considérables. L’appropriation de cette question est un enjeu de santé publique. L’OMS et l’ONU le font par leurs objectifs de développement durable (ODD) comme les organismes de normalisation et l’Union Européenne en encourageant une information publiée accrue. Au-delà de la régulation et de l’invitation au reporting externe, il est temps d’inciter à l’intégration de ces objectifs dans le management de ces entreprises ; d’où la proposition d’un modèle adapté aux entreprises du secteur agroalimentaire susceptible de répondre aux attentes de leurs parties prenantes.
Enhancing Connectivity for Remote Monitoring and Management Through IoT Empowerment
Authors: Singh Kashish , Kaur Jaspreet
Published: September 2024

This chapter investigates the use of internet of things (IoT) technologies into healthcare systems to enhance remote monitoring and administration. This study investigates the utilisation of internet of things (IoT) devices to facilitate instantaneous gathering, evaluation, and exchange of information between patients and healthcare professionals, hence improving the ease of access, effectiveness, and standard of healthcare. Healthcare personnel can utilise the internet of things (IoT) to remotely monitor patients' health metrics, identify any irregularities, and swiftly respond. This approach promotes proactive healthcare management and alleviates the strain on conventional healthcare facilities. The study highlights the capacity of the internet of things (IoT) to revolutionise healthcare provision and enhance patient results.
Switching Power Supply Boost Converter Using 180 nm CMOS Technology
Authors: Mesbah Fatima , El Khadiri Karim , Jamil Mohammed Ouazzani , El Alaoui Mustapha , Qjidaa Hassan , Chenoun Driss , Tahiri Ahmed
Published: September 2024

DC-DC (direct current) boost converters are used in a variety of applications, including battery packs for electric vehicles, power sources for white LEDs (light-emitting diode) and portable applications. This study offers a complete circuit design for a DC-DC boost converter using the cadence software for use in portable applications. The control circuits are composed of a bandgap, a voltage divider, a comparator, a ring oscillator, and a buffer. An inductor, Schottky diode, capacitor, and resistor serve as the load in the circuit's boost portion. This work discusses the design, simulation, and architecture of a converter for CMOS (complementary metal-oxide-semiconductor) switched power supply (SPS) which is included in CMOS 180nm technology to function at high frequency (287.1 MHz), and its objective is to convert voltages from 1.8 V to 3.3 V with a charge of 500Ω, being the implementation area of the circuit layout 0.435〖” ” mm〗^2.
Pain is Modulated Differently Between Females With and Without Patellofemoral Pain: Factors Related to Sensitization
Authors: Sigmund Kemery J. , Bement Marie K. Hoeger , Huddleston Wendy E. , Ebersole Kyle T. , Earl-Boehm Jennifer E.
Published: September 2024

Context

Patellofemoral pain (PFP) has poor long-term recovery outcomes. Central sensitization describes central nervous system changes altering pain modulation, which can complicate recovery (poorer prognosis and worse function). Signs of central sensitization include amplified pain facilitation, pain hypersensitivity, and impaired pain inhibition, which can be measured with temporal summation of pain (TSP), pressure pain thresholds (PPTs), and conditioned pain modulation (CPM), respectively. Sex differences exist for these test responses, but female-only PFP investigations of sensitization are uncommon. Understanding pain modulation in females with PFP could improve treatment protocols.

Objective

To determine whether females with PFP exhibit signs of central sensitization (greater TSP, lower PPTs, and reduced CPM) compared with pain-free females.

Design

Cross-sectional study.

Setting

Laboratory.

Patients or Other Participants

Thirty-three females ([20 PFP, 13 pain free]; age: PFP 29.2 ± 7 years, pain free 28 ± 7 years; height: PFP 166.7 ± 5.9 cm, pain free 166 ± 9.5 cm; mass: PFP 66.7 ± 9.6 kg, pain free 69.3 ± 7.5 kg).

Main Outcome Measure(s)

Temporal summation of pain was assessed with 10 punctate stimuli applied to the knee and calculated by the difference in pain intensity between beginning and end responses. Pressure pain thresholds were tested at 4 sites (3 for local hypersensitivity [knee] and 1 for widespread hypersensitivity [hand]). Conditioned pain modulation was conducted by comparing PPTs during 2 conditions (baseline and ice immersion). Conditioned pain modulation response was defined as the percent difference between conditions. Between-groups differences in TSP response were analyzed with a Welch test. Separate Welch tests analyzed group comparisons of PPTs and CPM responses at 4 sites.

Results

Females with PFP exhibited greater TSP response (P = .019) and lower CPM response at patella center (P = .010) and hand sites (P = .007) than pain-free females. Pressure pain thresholds group differences were not observed at any site (P > .0125).

Conclusions

Females with PFP modulate pain differently than pain-free females. Clinicians should recognize signs of central sensitization and their potential effect on treatment options.
Persuading doctors what to prescribe
Authors: Jobson Roy
Published: September 2024

No abstract available.
How to design education on mental disorder for general practitioners in South Africa
Authors: Mash B.
Published: September 2024

Objective: This study looks at how the WHO programme Mental Disorders in Primary Care should be adapted for GPs in the South African context in order to positively impact the recognition and management of mental disorders.Design: Participatory action research was used to adapt the WHO programme. There were 3 phases to the study. Firstly a co-operative inquiry group of 10 GPs adapted the WHO materials. Secondly the findings of the inquiry were incorporated into the design of a web-based distance education programme.Thirdly the web-based programme was evaluated by means of an action inquiry with the 21 registered GPs.Setting: South African general practitioners working in both public and private practice.Results: The findings of the study are presented as a model of the primary care consultation with a specific focus on the recognition and management of mental disorders. The approach includes the use of one hypothesis for 'mental problems' and assessment in the 'lobby' of general practice. Six governing variables for this approach are described: cues, communication skills, continuity of care, confidence, course tools and community resources.Conclusion: This study presents a practical model of the primary care consultation, which focuses on an approach to the recognition and management of mental disorders. This model has been used to adapt the WHO programme for the South African context. The model may be of use to general practitioners, educational designers, teachers of family medicine / primary care as well as district managers who wish to enhance the quality of care for patients with mental disorders.
Rural Health Issues
Authors: Archer Lawrence , Couper I.
Published: September 2024

No abstract available.
Osteo-Arthritis of the scaphoid-trapezium-trapezoid joint (STT joint) of the wrist
Authors: Mennen U.
Published: September 2024

No abstract available.
Caring for patients and their disorders
Authors: Jobson Roy
Published: September 2024

No abstract available.
Injections and Patient Satisfaction in Zulu-Speaking Patients
Authors: Niebuhr H.F. , Whitfield M.J.
Published: September 2024

One of the main objectives in a consultation is for patients to leave the consulting room feeling satisfied with their consultation. Satisfied patients are more likely to remain with a physician, keep appointments, comply with treatment and refer other patients to their physician. Among the factors that allegedly influence Zulu speaking patients' satisfaction is that of receiving an injection as part of the consultation. In a study about patient perceptions Mfenyana said: "...the majority of black people preferred an injection every time they consulted their doctor...". Giving injections to Zulu speaking patients has become routine in many practices in the belief that this is what patient want. Injection therapy is common throughout the developing world3 and the reasons for its popularity remain unanswered. This study was done to measure satisfaction in those who did receive an injection compared with those that did not receive an injection.
Rural Health Issues
Authors: Marincowitz Gert , Jenkins Loius , Cameron David , De Vries Elma , Reid Steve , Vamela M.B. , Dlomo Themba
Published: September 2024

No abstract available.
Correlation between the Serum Fatty Acids and Insulin in Gestational Diabetes
Authors: Alva Priya D. , Naresh Sriram , Rai Srinidhi , Nalilu Suchethakumari
Published: September 2024

Background:

Gestational diabetes mellitus (GDM) is defined as any degree of glucose intolerance that develops or is first recognized during pregnancy. Pregnancy is a diabetogenic condition marked by hyperinsulinemia and insulin resistance. In the early stages of pregnancy, maternal hormones enhance the production of insulin together with greater peripheral utilization, resulting in lower maternal blood sugar. Despite several research, the pathophysiology of GDM remains unknown, and the results acquired thus far point to a complicated process of interaction between multiple genetic, metabolic, and environmental variables.

Methods:

The aim of the present study was to find the correlation between serum fatty acid and insulin in GDM. Serum fatty acids were estimated by gas chromatography. Serum insulin levels were estimated using an enzyme-linked immunosorbent assay kit.

Results:

In the present study, we have collected serum samples from 50 pregnant women with GDM and normal pregnant women. We observed significantly increased levels of saturated fatty acids such as myristoleate and methyl palmitate, omega-3 fatty acids, α-linolenic acid, and omega-6 fatty acids, arachidonic acid.

Conclusion:

Alterations in plasma-free fatty acid (FFA) content or profile may contribute to insulin resistance. Furthermore, several FFAs can predict GDM in early pregnancy and are highly related to fetal growth and development, as well as the presence of macrosomia. Finally, proper fatty acid intake should be examined before and during pregnancy to optimize mother and newborn outcomes and introduce new preventive and therapeutic options for GDM.
Subinhibitory Concentrations of Kojic Acid Reduce Enterotoxins A and α-hemolysin Production in Staphylococcus aureus Isolates
Authors: Eslamifar Masoumeh , Kaboosi Hami , Saeedi Majid , Valadan Reza , Ghadikolaii Fatemeh Peyravii
Published: September 2024

Background:

Staphylococcus aureus (S. aureus) is one of the most significant human pathogens that causes various sorts of diseases and invasive infections. Recently, due to the resistance of this bacterium to several medications, it has become difficult to treat infections caused by it. The use of biological compounds to control infections might be a solution to this challenge. This study aimed to investigate the influence of kojic acid (KA) on the expression of some virulence factors of S. aureus.

Methods:

Clinical samples were collected from hospital sources. The standard diagnostic test and molecular techniques were used to identify S. aureus strains. Minimal inhibitory concentrations (MICs) of KA were determined according to guidelines of the Clinical and Laboratory Standards Institute. The expression levels of α-hemolysin (hla) and enterotoxin A (sea) genes were measured in the presence and absence of KA using a real-time polymerase chain reaction technique. The obtained data were analyzed using standard statistical methods in SPSS software (version 16) and Prism GraphPad software. P < 0.05 was considered statistically significant in the comparative data.

Results:

The results indicated that the values of minimum inhibitory concentration (MIC) of S. aureus after KA treatment were 512 μg/mL. As a result, the expression of the hla gene was decreased 9 fold and the expression levels of the sea gene were decreased 2.7 fold.

Conclusions:

In this study, the desirable effects of KA on S. aureus strains were observed. In conclusion, the application of KA potentially reduces the virulence factors of S. aureus. These promising results can breathe hope in the fight against pathogenic S. aureus strains by repressing their virulence factors.
Investigating the Expression of miR 203a 3p and Its Role in Inflammatory Response in Severe Preeclampsia of Iraqi women Patients – A Comparative Study
Authors: Jaber Shatha Qasim , Kadhim Ali Saad , Al Kateeb Anfal Izaldeen
Published: September 2024

Background:

Preeclampsia (PE) has long been a feared condition impacting women and their pregnancies. Researchers have recently discovered the role of miR203a-p3 in various diseases. The aim of the study was to explore the role of miR203a and measure its levels in pregnant patients, along with reviewing the advancement of inflammatory markers related to disease.

Methods:

Seventy serum samples and erythrocyte sedimentation rate (ESR) tubes were collected from pregnant women aged 25–33 who were diagnosed with serious PE. Upon this, 15 samples were chosen for testing of the deemed levels and gene expression of miR203a. Laboratory evaluation was mainstreamed in the study, including measurements of serum creatinine, blood urea, and uric acid. These parameters were quantitated using turbidity techniques and coulometric methods for C-reactive protein. In addition, we appraised the ESR uptake by the time method and examined fibrinogen by the agglutination time method. We quantified interleukin-6 (IL-6) using an enzyme-linked immunosorbent assay.

Results:

The serum levels of biomarkers and inflammatory tests differed significantly in the patients compared to controls. Similarly, a rise in gene expression resulted in an abatement in the level of miR203-p3, and there was a positive direct correlation between them.

Conclusion:

Patients exhibit high levels of biomarkers and IL-6, along with reduced concentration and expression of miR203a. There is a significant positive correlation between miR203a and disease. Finally, miR203 has played an active role in the current disease.
Distribution of Carbapenemase Genes among Carbapenem-Resistant Klebsiella pneumoniae Isolates from the Patients in Najaf, Iraq
Authors: Mohanna Zahraa A. , AL-Yasseen Ahlam Kadhum
Published: September 2024

Background:

Carbapenem-resistant Klebsiella pneumoniae (CRKP) is a global threat, causing serious community- and hospital-acquired infections with limited treatment options. Understanding the local epidemiology of CRKP is crucial for guiding antimicrobial stewardship and infection control measures. This study aimed to investigate the phenotypic characteristics, antimicrobial resistance profiles, and carbapenemase genes among CRKP isolates from the patients in Najaf, Iraq.

Methods:

This cross-sectional research was performed at diverse hospitals and centers in Najaf, Iraq, from September 2023 to March 2024. The study was approved by the Ethics Committee of Kufa University. CRKP isolates were collected from various health-care facilities and tested for hypermucoviscosity, antimicrobial susceptibility, and carbapenemase production using phenotypic methods. The presence of carbapenemase genes (blaNDM, blaVIM, blaKPC, blaOXA-48, blaOXA-23, and blaOXA-51) was examined by polymerase chain reaction.

Results:

Of the 27 CRKP isolates, 9 (33.3%) exhibited a hypermucoviscous phenotype. Regarding antimicrobial resistance, 12 (44.4%) were multidrug resistant, 14 (51.9%) were extensively drug resistant, and 1 (3.7%) was pandrug resistant. Phenotypic carbapenemase production was detected in 5 (18.5%) and 11 (40.7%) isolates by the modified Hodge test and E-test metallo-β-lactamase strips, respectively. Molecular analysis revealed that all CRKP harbored the blaOXA-51 gene, whereas blaNDM, blaOXA-23, and blaVIM were detected in 70.4%, 40.7%, and 11.1% of the isolates, respectively. Neither blaKPC nor blaOXA-48 genes were found. In addition, 22 (81.5%) isolates carried multiple carbapenemase genes.

Conclusions:

The high prevalence of blaOXA-51 and blaNDM carbapenemases, along with the high rates of multidrug resistance among CRKP isolates in Najaf, Iraq, are alarming. This necessitates the immediate implementation of effective antimicrobial stewardship and infection control measures to prevent the further spread of these difficult-to-treat pathogens.