bluuebunny/crossref_metadata_2025 huggingface dataset:
Seven Benefits of Employing Dynamic Health in Clinical Settings
Authors: EBSCO Information Services
Published: January 2023

Dynamic Health™, from EBSCO Information Services, is an evidence-based clinical decision support resource designed for quick retrieval of diagnosis and treatment information at the point of patient care.
BIOÉTICA E CONTROLE JURÍDICO QUANTO À SELEÇÃO DE EMBRIÕES HUMANOS CRIPTOPRESERVADOS NA BUSCA DO MELHORAMENTO GENÉTICO
Authors: Fé Francisca Cecília de Carvalho Moura , Franck Junior Wilson , Brandão Juliana Franck , Nogueira Lília de Sousa , Rodrigues Vanessa do Nascimento , Giaretta Francisco Secco
Published: January 2023

A inteligência humana alcançou a capacidade tanto de aumentar sua expectativa de vida quanto de melhorar a genética antes mesmo de um indivíduo nascer. No entanto, com os avanços da tecnologia e da engenharia genética, começou-se a questionar a atuação da medicina no campo da reprodução no que diz respeito aos parâmetros éticos, legais e sociais. Nesse sentido, o presente artigo trata da bioética e do controle jurídico quanto à seleção de embriões humanos criptopreservados na busca do melhoramento genético. O artigo tem como objetivo analisar se essa prática seria uma espécie de eugenia da nossa época e avaliar o limite moral e ético das modificações embrionárias. O presente artigo tem o caráter metodológico hipotético-dedutivo, realizado por meio de uma pesquisa bibliográfica.
KUALITAS ROHANI JEMAAT FILADELFIA DALAM WAHYU 3:7-13 SEBAGAI PANUTAN BAGI ORANG KRISTEN MASA KINI
Authors: Tataming Andrias
Published: January 2023

This article is to conduct a study on the Spiritual Qualities of the Philadelphia’s church in Revelation 3:7-13 as a Role Model for Christians nowadays. As a believer in Christ must understand correctly how to live, have the spiritual quality of growing, which is good and strong. Spiritual growth begins with a correct understanding of the Word, and it is the Word that will move every believer to continue doing what is right before God. Therefore a person's faith is based on his spiritual quality. The church in Philadelphia is a congregation that has a strong and basic spirituality. The belief and spiritual quality of the Philadelphian congregation in Christ is expressed through the way of the church's life, which obeys the word, does not deny God's name, waits diligently on God, and faithfully preaches the gospel. This way of life is a role model in the Christian life.

Artikel ini adalah untuk melakukan suatu penelitian mengenai Kualitas Rohani Jemaat Filadelfia Dalam Wahyu 3:7-13  Sebagai Panutan Bagi Orang Kristen Masa Kini. Sebagai orang yang percaya kepada Kristus harus Mengerti dengan benar bagaimana seharusnya hidup, memiliki Kualitas rohani bertumbuh, yang baik dan kuat. Pertumbuhan secara spiritual dimulai dengan pemahaman yang benar tentang Firman, dan Firman itulah yang akan menggerakkan setiap orang percaya untuk terus melakukan perbuatan-perbutan yang benar dihadapan Tuhan. Karena itu iman seseorang didasarkan pada kualitas rohaninya. Jemaat di Filadelfia merupakan jemaat yang memiliki rohani yang kuat dan mendasar. Keyakinan dan kualitas rohani jemaat Filadelfia kepada Kristus dinyatakan melalui cara hidup jemaat, yang menuruti firman, tidak menyangkal nama Tuhan, tekun menantikan Tuhan, dan setia memberitakan Injil, cara hidup ini merupakan suatu Panutan dalam kehidupan kekristenan.
KOMPARASI KONSEP ESKATOLOGI DISPENSASIONALISME DENGAN COVENANT THEOLOGY TENTANG KERAJAAN SERIBU TAHUN
Authors: Bili Agustina , Balang Jhonston Daud
Published: January 2023

Abstrak

Permasalahan dalam tulisan ini terletak pada isu doktrin eskatologi tentang kerajaan seribu tahun, khususnya dalam pandangan dispensasionalisme dengan covenant theology. Munculnya isu ini karena sebagian kekristenan menafsirkan kerajaan seribu tahun dengan cara penafsiran yang berbeda-beda oleh penerus Agutinus. Pembahasan ini bertujuan untuk memperbanyak pembasahan tentang kerajaan seribu tahun. Karena penitik beratan pada “kerajaan seribu tahun”, maka tulisan ini menggunakan pendekatan kepustakaan. Tulisan ini akan menjabarkan kerajaan seribu tahun menurut pakar utama, hasil kerajaan seribu tahun menurut dispenasionalisme dengan covenant theology. Kesimpulan dari tulisan membuktikan bahwa kerajaan seribu tahun benar-benar akan terjadi di masa depan.   

 

Kata Kunci: Komparasi-konsep-eskatologi-dispenasionalisme-covenant-theology-tentang-kerajaan- seribu-tahun.
PERAN PENDIDIK KRISTEN DALAM PENCEGAHAN KENAKALAN REMAJA DALAM MENYONGSONG MASYARAKAT 5.0
Authors: Sagala Lenda Dabora J.F. , Monika Thia , Desi Elsha Triani Ibi
Published: January 2023

The lives of today's teenagers determine the future of a nation because teenagers are the nation's future assets. However, recently juvenile delinquency behavior is often very concerning. Amid this situation, the role of Christian educators is very much needed to foster and guide teenagers so that they have good character. The formulation of the problem in this paper is what is the role of Christian religious teachers in the church in preventing juvenile delinquency? So the purpose of this study was to determine the role of Christian religious teachers in the church in preventing juvenile delinquency. This study uses a library research approach. From this research, the results are, first, Christian educators play a role in implementing Christian hospitality. This means that Christian educators should love teenagers and make it happen by providing motivation and encouragement to teenagers to become good people. Second, play a role in conducting counseling guidance. Counseling carried out on adolescents is expected to provide true knowledge about God and satisfaction in receiving the counseling service. Third, play a role in developing youth talents. Because of this role, teenagers can develop the talents that exist in themselves and teenagers can do more positive and good activities. Fourth, make discipleship of the youth. Because teenagers must be guided to stay centered on God.
IMAN KRISTEN SEJATI: PROSES BERTUMBUH DAN BERBUAH DALAM KEBENARAN BERDASARKAN MATIUS 13:24-30
Authors: Doma Yabes , Christiani Abeta
Published: January 2023

Dewasa ini, kekristenan seringkali dipahami dan dinilai hanya sebatas agama saja. Dengan adanya sebuah pemahaman dan penilaian yang demikian, cukup sulit untuk memiliki iman Kristen yang sejati. Adapun metode yang digunakan dalam penelitian ini adalah analisis terhadap teks Alkitab dalam Matius 13:24-30. Dalam analisis ini, penulis menggunakan berbagai sumber pustaka, seperti buku-buku tafsiran, leksikon, dan berbagai sumber dari jurnal ilmiah. Melalui penelitian yang dilakukan, diketahui bahwa tantangan iman orang percaya diibaratkan lalang yang tumbuh diantara gandum. Untuk dapat bertahan menghadapi tantangan tersebut, diperlukan hidup yang mengandalkan Tuhan. Orang yang mampu bertahan menghadapi berbagai tantangan hidup adalah orang yang memiliki iman Kristen yang sejati. Ketika seseorang memiliki iman Kristen yang sejati, maka ia akan bertumbuh dan hidup menghasilkan buah kebenaran.
DISTINGUISHING TRAITS OF SATIRE AND HUMOR
Authors: Dr. Muhammad Shahbaz  , Dr. Parveen Akhtar Kallu  , Wattoo Dr. Irfan Tauheed
Published: January 2023

Humour and satire have become a trend in every language of the world, for which humourous writers have devised new tactics and resources. Especially in Western literature, very high means and tools were used to promote humour and satire. The influence of which some excellent examples of humorous writing can be seen in Eastern languages and literature as well. There is no other opinion that the importance of these tactics and resources for the growth of humour and satire is evident in every piece of literature of the world. In the article under study, the scribe has tried to present in a critical and research-oriented way the same tactics and resources used by the humourous writers to cultivate humour and satire.
NAZAR ABID’S NAATIYA POETRY
Authors: Dr. Sadaf Ambreen  , Dr. Bismina Siraj  , Ms. Nuzat Rauf
Published: January 2023

Naat is the versified poetry in honour of the Prophet of Islam, Muhammad (PBUH). From his famous companion Hassaan Bin Sabit till now every Muslim poet desires to write some verses in his honour. So Dr. Nazar Abid tried this. He compiled Berg-e-Naat. Dr. Nazr Abid has so far made Urdu ghazal a major source of his poetic expression, but now he is fortunate to be attracted to Urdu Naat as well. At the same time, it is a source of expression for various aspects of the Seerah. His collection of Natiya poetry. Berg-E-Naat was published in February 2022. This article presents a literal analysis of the dedicated poetry of Dr. Nazar abid with particular reference to its thought and artistic aspect of Naat. In which he showed his love through words.
A Highly Selective Colorimetric and “Turn-Off” Fluorimetric Probe Based on Unsymmetrical Naphthalene Formaldehyde Derivatives for the Detection of CN− in Aqueous Media
Authors: Yao Ying , Gui Kai , Fu Xu-Mei , Liu Hui-Xin , Hu Jing-Han
Published: January 2023

A novel hydrazone-based CN− fluorescent probe, HNT, was synthesized by 1-hydrazine methyl-2-naphthol and 2,3,4-trihydroxybenzaldehyde. CN− has stronger basicity and a superior hydrogen-bonding ability than other anions. Therefore, CN− can deprotonate naphthalene hydroxyl in fluorescent probe HNT, which induced the bright yellow fluorescence that was quenched before changing the color of the solution from yellow to orange. This color change indicates that fluorescent probe HNT showed selective recognition of CN− and was not interfered with by other anions. HNT can quantitatively detect CN−, and the detection limit is 6.93 × 10-7 M. The manufactured HNT test strip could also quickly detect CN−, which indicates that HNT has certain application value.
COMPARING THE MOLECULAR PROPERTIES OF ENVIRONMENTAL HORMONES WITH HEARTBEAT CHANGES IN DAPHNIA MAGNA
Authors: MOON YESEUNG , JEON RACHEL
Published: January 2023

Rationale: Environmental hormones (EH) disrupt the integrity of the endocrine system. Many chemical compounds act as endocrine disruptors, such as insecticides, herbicides, plasticizers. If these chemical compounds spread outside their area of intended use, they can stay in the environment and flow down into local bodies of water and wreak havoc upon ecosystems in the area. So, understanding the underlying relationship of the EHs with the physiology of an organism may be important for the design of chemical structures that could minimize the adverse effects for the future compounds.

Methods: For this study, we chose 10 environmental hormones of BFR, DMT, LCH, DMA, TTS, MLT, ANN, CFT, GPS and GCH to examine the acute cardiac effects for 30 minute incubation in 1:10 serial dilution solutions.   The heartbeat rates and their differences were evaluated at pre- and post-incubation, which was then converted into their heartbeat change% based on the pre-heartbeat rates.  Then, the heartbeat change % for the individual EH was put on a regression analysis with molecular properties such as molecular weight, XlogP, topological polar surface area (TPSA), complexity, solubility and heavy atom count.

Results: The leading coefficient of polynomial function showed relationship with those molecular properties with regression coefficient R2 from 0.1163 to 0.3182. The study should be significantly recognized in that the relationship of acute cardiac effects to the molecular properties were able to quantify as a unique attempt to elucidate.  More study might be needed for in-depth clarification in the constants of the polynomial relationship.
AN OVERVIEW ON HEREDITARY AND ACQUIRED HYPERCOAGULABILITY
Authors: HUSSAIN MOHAMMED SALAH , DAWS SUMYA HASSAN , ALHAZMI ESSA IBRAHIM , JAN MANSOUR ABDULRAHIM , GHAMRI SAHAD SAMI , ALHUDIRES KOUTHER MUTLAQ O. , ALHASSAN OSAMAH ABDULAZIZ A. , HUSSAIN FAHAD AMJAD A. BIN , HUSSAIN ABDULLAH AMJAD A. BIN , NASSER ADAWI, ZAINAB Y. , M. ADAWI, YAHYA AHMED , A. ALQAHTANI, ABDULAZIZ KHALID
Published: January 2023

A typical definition of hypercoagulability is the predisposition to develop venous thromboembolism due to an underlying hypercoagulable state caused by hereditary or acquired blood coagulation or fibrinolysis problems. Clinical signs of hypercoagulability can be fatal or extremely damaging. About 80% to 90% of patients can have hypercoagulability diseases accurately recognised. Determining the origin of hypercoagulability may influence the kind and length of treatment for the accompanying thrombosis. As a result, hypercoagulability is not a single, unified disease process but rather a collection of risk factors that may or may not lead to thrombosis, depending on the severity and number of risk variables as well as environmental exposures. The former includes prothrombotic polymorphisms in the genes encoding for factor V (i.e., factor V Leiden) and prothrombin, as well as shortages of natural anticoagulants such antithrombin, protein C, and protein S. It also includes elevated values of clotting factors (particularly factor VIII). The latter problems mostly include hyperhomocysteinemia, acquired elevations of coagulation factors or acquired reductions of natural inhibitors, malignancy, and antiphospholipid antibody syndrome.
SCREENING OF AFRICAN AND FRENCH MARIGOLD GERMPLASMS AGAINST Tetranychus urticae KOCH (ACARI: TETRANYCHIDAE) UNDER FIELD CONDITIONS
Authors: BAMEL KARUNA , GULATI RACHNA , KHUSHBU . , JANGRA MONIKA , BAMEL KESHAV
Published: January 2023

The germplasms of African and French marigold were screened at Research Farm Area, Department of Horticulture, CCS Haryana Agricultural University, Hisar, Haryana against the two spotted spider mite, Tetranychus urticae (TSSM) in the winter season from first week of October to first week of March, 2018. The germplasm tall orange African sheltering lowest mite population (9.82 mites/leaf) was marked as the least susceptible and Hisar Jafari-2 French with 32.21 mites/leaf was categorized as highly susceptible for T. urticae infestation. Mite population was recorded weekly and significantly higher number of mites was recorded on grown up leaves followed by tender and older leaves of marigold plants. Irrespective of the germplasm, the mite number was found to significantly increase with each observation period till the attainment of peak in population in the month of January (35.51 mites/ leaf) while their least population was recorded in the month of October (6.65 mites/leaf). In general, French germplasms were comparatively more susceptible to T. urticae infestation as compared to African germplasms.
Queue Information System at One-Stop Integrated Services in the Ministry of Religion's Office of Dharmasraya Regency
Authors: Emiliya Siska , Purnomo Wulan Andang , Lesmana Lido Sabda , Ali Gunawan
Published: January 2023

The Office of the Ministry of Religion is one of the Government Agencies that has inaugurated the One-Stop Integrated Service. In a one-stop integrated service already using a computer as a data processing device, but based on observations of researchers the Office of the Ministry of Religion applies a queuing system manually where registration officials call verbally, so visitors want to overtake each other and inconvenience and lack of discipline is queued. And observations from researchers of the system are ineffective and cause complaints from visitors. To improve the quality of service to visitors, a desktop-based Queue Information System application is created using the java programming language. This program is expected to help improve services so as to create optimal service.
Tanzimat Döneminde Van
Authors: KARA Selamet
Published: January 2023

Tanzimat Döneminde Van adlı eserin içeriğinde Tanzimat'ın dağılmakta olan imparatorluğun ayakta kalma çabasının ürünü olduğu, Afrika'dan Suriye, Irak ve diğer Arap memleketleri ile Anadolu ve Rumeli'deki Türkmen, Kürt, Arap ve Arnavut gibi göçebe ve ya da yarı göçebe şeklinde yaşayan ve devlet otoritesini tanımayan zümrelerin, merkezi devlet anlayışı gereği kontrol altına alınma dönemidir.
Penggunaan Pendekatan Contextual Teaching And Learning Berbantuan Media Audio Visual Untuk Meningkatkan Hasil Belajar Matematika
Authors: Suradi Futeri Maharani , Sumiati
Published: January 2023

Penelitian Tindakan Kelas (PTK) ini dilatarbelakangi oleh rendahnya hasil belajar peserta didik kelas I Madrasah Ibtidaiyah dalam pembelajaran matematika. Penelitian ini menjelaskan bagaimana pembelajaran kontekstual berbantuan media audio visual dapat meningkatkan hasil belajar matematika peserta didik kelas I. Subyek penelitian ini adalah peserta didik kelas I MIS Darul Ihya Kecamatan Ciomas Kabupaten Bogor. Penelitian ini menggunakan metode Penelitian Tindakan Kelas yang diadaptasi dari Kemmis Mc Taggart, dan teknik pengumpulan data meliputi lembar tes tertulis, rubrik penilaian, dan observasi selama kegiatan pembelajaran. Perkembangan proses pembelajaran dari siklus I ke siklus II meningkat, terlihat dari semakin kondusif dan antusiasnya kegiatan selama proses pembelajaran. Hasil penelitian menunjukkan bahwa hasil belajar peserta didik pada pembelajaran matematika pada pokok bahasan penjumlahan dan pengurangan mengalami peningkatan pada setiap siklusnya. Hasil pra siklus menunjukkan hanya 40% peserta didik yang mencapai KKM. Kemudian pada siklus I peserta didik yang mencapai KKM sebesar 70%. Pada siklus II, 85% peserta didik menyelesaikan KKM. Dengan demikian, dalam penelitian ini hasil belajar peserta didik pada pembelajaran matematika dengan menggunakan Contextual Teaching and Learning berbantuan media pembelajaran audio visual meningkat sebesar 15%, hasil belajar peserta didik di MIS Darul Ihya Kabupaten Ciomas.
Penggunaan Pendekatan Saintifik sebagai Best Practice Pembelajaran di Sekolah Dasar
Authors: Meriyati
Published: January 2023

Perubahan kurikulum 2013 dapat dilihat pada aspek pembelajaran dan penilaian pembelajaran. Pembelajaran ditekankan dengan pendekatan saintifik, dan penilaian pembelajaran mengacu pada penilaian autentik. Hal ini bertujuan untuk melaksanakan pembelajaran yang baik (best practice) dengan pendekatan saintifik di kelas VI B untuk meningkatkan partisipasi siswa dan bersosialisasi dengan guru di sekolah. Penulisan ini menggunakan metode studi kasus karena adanya permasalahan akibat penerapan pembelajaran dengan pendekatan saintifik, dan masih banyak guru yang mengalami kesulitan. Pengumpulan data dan informasi penelitian dikumpulkan melalui wawancara, kegiatan praktik, dan observasi. Hasil pelaksanaan kegiatan best practice pembelajaran saintifik di SDN Leuweungkolot 02 Kecamatan Cibungbulang Tahun 2019, perencanaan pembelajaran diawali dengan menemukan masalah di sekolah, mendefinisikan masalah, mengajukan ke sekolah, mengamati pembelajaran duduk kepada guru senior, dan menerapkan pembelajaran berbasis pendekatan saintifik di sekolah. tahap evaluasi pembelajaran, termasuk masukan dan saran dari guru. Hasil kegiatan best practice ini dapat meningkatkan pemahaman guru terhadap pembelajaran dengan menggunakan pendekatan saintifik. Menggunakan pendekatan saintifik sebagai best practice dalam proses pembelajaran dengan menggunakan pendekatan saintifik di SDN Leuweungkolot 02 Kecamatan Cibungbulang Kabupaten Bogor menunjukkan adanya peningkatan partisipasi siswa dan kesiapan guru melalui kegiatan observasi sampai dengan tahap mengomunikasikan.
Penggunaan Model Cooperative Learning Tipe Talking Stick Untuk Meningkatkan Hasil Belajar Siswa Pada Materi Masalah Sosial
Authors: Irmawati Sri , Prasetyo Teguh , Hartono Rudi
Published: January 2023

Interaksi di kelas akan memiliki tujuan dalam kegiatan pembelajaran untuk meningkatkan hasil belajar siswa. Namun proses pembelajaran seringkali monoton sehingga siswa kurang memperhatikan dan pasif dalam pembelajaran. Peneliti menggunakan Model Pembelajaran Kooperatif Tipe Talking Stick untuk meningkatkan hasil belajar siswa pada Materi Soal IPS Kelas IV metode dan model pembelajaran di SDN Cianten 02 dan ketersediaan media pembelajaran. Penelitian ini dilakukan untuk meningkatkan hasil belajar siswa kelas IV IPS dengan menggunakan Metode Pembelajaran Kooperatif Tipe Talking Stick. Hasil penelitian sebelum tindakan, siswa yang mendapat nilai kurang dari 65 (KKM) sebanyak 15 siswa (62,5%), dan siswa yang mendapat nilai lebih dari 65 sebanyak sembilan siswa (37,5%). Pada siklus 1, lima siswa mendapat nilai kurang dari 65 (20,83%) dan 19 (79,17%), dengan nilai rata-rata 68,0. Pada siklus 2, 1 siswa (4,17%) mendapat nilai kurang atau sama dengan 65, dan 23 siswa (95,83%) dengan nilai rata-rata 80,2. Hasil penelitian dua siklus ini sudah melebihi indikator penelitian yang diinginkan yaitu 80%, sehingga penelitian telah tuntas pada siklus 2. Dengan demikian, Model Pembelajaran Kooperatif Tipe Talking Stick Hasil Belajar IPS siswa kelas IV SDN Cianten 02, dapat ditingkatkan.
The role of calcium and calcium regulating hormonal system in the mechanisms of COVID-19 contagiousness and severity
Authors: Khudaverdyan D.N. , Hasratyan H.A. , Melkumyan K.V. , Ghambaryan H.K. , Abovyan L.A.
Published: January 2023

Calcium is involved in all vital processes of the body: synaptic transmission, memory development, immunity, blood clotting, heart contractions, etc. In this regard, it is important to understand the involvement of calcium in the development of SARS-CoV-2 virus infection and COVID-19 disease.
We have studied the existing scientific literature, looking for the involvement of both calcium and calcium-regulating hormones (parathyroid hormone, calcitonin, vitamin D) in COVID contagiousness and severity of disease.
Separately, both hypocalcemia and vitamin D deficiency have been identified in a number of large clinical trials as a predictor of mortality in patients hospitalized with COVID-19. Angiotensin-converting enzyme-2 plays a key role in contagiousness with the SARS-CoV-2 virus, and its formation is a calcium-calmodulin-dependent process. In our opinion, in order to prevent the penetration and spreading of the virus in the body, this link should be targeted with the usage of drugs that activate the calcium calmodulin system. Calcium blockers used parallel with hypocalcemia, to some extent, reduce the spreading of the virus in the body in the acute phase of the disease, but it is possible that in the future they lead to deeper and long-term complications - cognitive dysfunction.
However, we did not find any study in the literature that aimed to identify calcium-dependent mechanisms in a complex, dynamic study of the same patients. Therefore, this question is still open in science, because without understanding how the amount of calcium-regulating hormones changes during the disease, without understanding how much phosphorus changes in parallel with calcium, it is impossible to get a complete picture of the disease on the role of calcium-dependent mechanisms in development. Only a summary of such combined data will allow us to reach a scientifically based conclusion, to explain the mechanisms by which hypocalcemia occurs, and by what possible mechanisms it can be prevented.
Cigarette Smoking, nicotine and Parkinson’s disease: Controversies in clinical trials data and medical practice.
Authors: Kesoyan A.A. , Arakelyan N.L. , Aloyan D.A. , Karapetyan A.A. , Manvelyan H.M.
Published: January 2023

It’s well known that smoking cigarettes is causally linked to a number of serious mortal diseases. These include laryngeal, lung, bladder, and digestive tract cancers, chronic obstructive pulmonary disease and a number of cardiovascular diseases, such as aortic aneurysm, stroke, and ischemic heart disease.
In 2014, U.S. Surgeon General Report states that smoking is causally associated with inflammation and impaired immune function, and that regular smokers are at higher risk of developing pneumonia, tuberculosis, and other airway infections. So the best way to avoid harm from smoking is to never start, and for smokers to quit.
However, evidence from epidemiological studies suggests a relationship between cigarette smoking and low risk of Parkinson’s disease. As a major component of tobacco smoke, nicotine has been proposed to be a substance for preventing against Parkinson’s disease risk, with a key role in regulating striatal activity and behaviors mediated through the dopaminergic system. Another data suggests quick deterioration and disease exacerbation after smoking cessation. Animal studies also showed that nicotine could modulate dopamine transmission and reduce levodopa-induced dyskinesias.
Smoking cessation, proposed because of the health issues as certainly reducing the risk of cardiovascular events and cancer, must be definitely accepted as major health paramount procedure, but in the case of Parkinson’s disease nicotine-substitute supplements must be provided. As a small amount of nicotine can saturate a substantial portion of nicotine receptors in the brain, nicotine from other sources, such as less harmful smoking advanced devices as well as diet, could be a promising therapeutic substance for motility support and protection against Parkinson’s disease.
Regional melatonin and somatostatin dependent mechanisms in pancreatic incretory activity and in intestinal bacterial homeostasis.
Authors: Muradyan Armen
Published: January 2023

For many years, it was generally accepted that melatonin and somatostatin have intracerebral sources of synthesis.
Melatonin is produced in the pineal gland and somatostatin in the hypothalamus. However, there are very informative data regarding the extracerebral sources of melatonin and somatostatin synthesis in numerous literary sources published over the past 60 years. At the same time, the biological purpose of extracerebral somatostatin and melatonin has been insufficiently studied. This article presents the readers with an analysis of modern literature and the results of own researches on the biological role of melatonin and somatostatin produced in the pancreas and intestinal tract.
Under experimental conditions on arginine-induced acute pancreatitis model in rats, structural and hormonal changes were studied in the pancreas, mucosa of the small and large intestines in regional pathological process using morphological, morphometric, immunomorphological and enzyme immunoassay methods.
According to the morphological and morphometric analysis results, gross dystrophic changes in the pancreas and intestinal mucosa were observed at relatively early stages of the pathological process – in 2 and 24 hours after the arginine administration. Immunomorphological studies established that the content of melatonin-positive secretory cells noticeably decreased, especially in the areas of mucosal damage in this very period of the pathological process in pancreas, in the mucous membrane of the small and large intestines. At the same time, the content of somatotropin in blood serum and pancreas markedly increased during the indicated period of the experiment.
Severe dystrophic processes on small intestinal mucosa, which are particularly expressed by inhibition of local melatonin-secreting cell function, apparently exclude the inhibitory effect of melatonin on somatostatin synthesis process in pancreas. It is not excluded that there is a directed activation of pancreatic delta cells responsible for the somatostatin synthesis at relatively early stages of “arginine pancreatitis”.
Based on our own researches in context with available very informative literature data, we can conclude that extrapineal melatonin and extrahypothalamic somatostatin should be given an important role in the integrative activity of organ-digestive system – the pancreas and small intestine.
Does cervical proprioception affect hand dexterity of physiotherapists with and without mechanical neck pain?
Authors: Kamal Hend Refaat , Fahmy Ebtesam Mohamed , Badawy Wanees Mohamed , Elserougy Hager Rasmy , Zaki Hoda Mohamed , Elsherif Abdelaziz Abdelaziz
Published: January 2023

Purposes. This study was conducted to compare between cervical proprioception and hand dexterity in physiotherapists with and without mechanical neck pain, and to determine the relationship between cervical proprioception and hand dexterity in physiotherapists. Materials and methods. Sixty physiotherapists (30 with chronic mechanical neck pain (G1), mild to moderate neck pain lasted more than 6 months and 30 healthy control (GII)). Both sexes were enrolled with; age ranged from 25 to 35 years, normal body mass index (BMI) and at least one year of practice of manual work. All participants undergone evaluation of cervical joint position error (JPE) using cervical range of motion device (CROM) through head-to-neutral repositioning (NHR) and head-to-target repositioning (THR) tests in flexion direction in addition to evaluation of hand dexterity using Purdue pegboard test. Results. There was statistically significant difference in median values of JPE and hand dexterity between both groups. There was statistically significant indirect medium to strong correlation between JPE in flexion (NHR and THR) and hand dexterity (in dominant and assembly tests). Conclusions. Physiotherapists with neck pain have impairment in cervical proprioception which in turn negatively affects hand dexterity. Hand dexterity is important functional property for physiotherapist to apply different manual techniques. So, impairment of hand dexterity may interfere with the efficiency of manual application.
Vita Mea: The Autobiography of Sir Herbert J.C. Grierson Cairns Craig
Authors: Craig Cairns
Published: January 2023

Herbert Grierson was only 28 when he was appointed Professor of English Literature at the University of Aberdeen in 1895; in the following quarter of a century he established himself as the most distinguished literary critic of his time: first, by the publication in 1912 of his edition of the poetry of the then little acknowledged seventeenth-century English poet John Donne, and subsequently by his influential anthology of The Metaphysical Poets, published in 1919. Because of Grierson, Donne became the most admired poet of some of the twentieth-century’s most influential poets, and the ‘Metaphysicals’ became the model for many of the most radical developments in twentieth-century poetry.
The Wars of Archibald Forbes
Authors: Fraser W. Hamish
Published: January 2023

With heroic journeys on horseback and on foot to get to the nearest telegraph station, Archibald Forbes transformed the profession of war correspondent into something recognisably modern. He was widely regarded as the greatest war correspondent of the nineteenth century and the model with whom all others had to compete. It was he, more than any other, who appreciated the public demand for immediacy and therefore the need to get reports from the front into the press as fast as possible. He transformed the fortunes of the Daily News by making extensive use of the telegraph: his brilliant descriptive writing shaped images of wars for a public greedy for information and excitement. Despite persistent health difficulties he covered in the 1870s the Franco-Prussian War, the Paris Commune, the Carlist Wars in Spain, the Serbian-Turkish War, the Russo-Turkish War, the occupation of Cyprus, the Afghan War, the Zulu War, the Indian Famine and the Prince of Wales’s visit to India. At the same time, he kept up a prolific output of articles in many of which he did not hesitate to challenge the assumptions of the military authorities, to criticise the generals and to press for modernisation of the army. He defended the freedom of war correspondents to report wars as they saw them against the growing pressures to have their work censored and controlled. When ill-health forced him to abandon war work he became a tireless lecturer in Britain, the United States, Australia and New Zealand and his predictions on the shape of future wars came all too true in 1914.
ANÁLISE TEÓRICA PELO MÉTODO DA RESISTÊNCIA DIRETA DE SEÇÕES DUPLAS DE PERFIS DE AÇO FORMADOS A FRIO SOB COMPRESSÃO
Authors: Zambrano Danilo Menezes , Alves Larissa Maria , Moreira Matheus Lessa , Nunes Riterson Jacques
Published: January 2023

The need for lighter, lower-cost construction has intensified, so the presence of cold-formed profiles has become common in civil construction, offering greater efficiency in the ability to withstand the current demands. The present article aimed at the theoretical study on the stability of double U and U lipped sections, composed of cold formed steel profiles, submitted to compression. Under the justification of analyzing the effectiveness of this type of structural element, with the help of the CUFSM Software that uses the Finite Strip Method, and verify the resistance by the Direct Strength Method (DSM). The objectives of this study were: to investigate the modeling in the CUFSM software for a double section with profiles connected to each other; and apply the DSM to the theoretical analysis of double sections with Brazilian commercial profiles. It was found that the variation in the number of connections influences the analysis and can reproduce the partial connection behavior. The application of folds proved to be efficient, with little influence on local instability and considerable influence on distortion instability. The DSM showed a loss of resistance for the models that presented a local failure mode, being, therefore, the most important factor regarding the resistance.
ARTEACHINGVR: O ENSINO DAS ARTES AUXILIADO PELA REALIDADE VIRTUAL NAS ESCOLAS DE ENSINO FUNDAMENTAL ESTADUAL BRASILEIRO
Authors: Nascimento Guilherme Gomes Leal do , Nascimento Margarida Maria Gomes Leal do , Siscoutto Robson Augusto
Published: January 2023

The art discipline aims to develop in the student a critical interaction with the complexity of the world and favor respect for the diversity of cultures and peoples. The current methodology in the classroom uses traditional and non-technological methods for teaching and learning this type of discipline, generating demotivation to the student. The insertion of technology in the classroom, such as Virtual Reality, can help in the abstraction of problems and concepts intrinsic to the discipline, motivating it in its teaching/learning process. However, there are few applications being used in public schools due to lack of resources or interest. Therefore, this paper presents a virtual reality tool that provides interactive three-dimensional virtual environments in order to assist the teaching/learning of students at the Brazilian elementary school of Art discipline. The virtual environments were evaluated by the project researchers by means of a specific usability questionnaire for this type of environment, obtaining a final average of 4.67 of 5.0, being considered suitable for use in the future in classrooms.
RECONSTRUÇÃO 3D DE CENAS E OBJETOS A PARTIR DE IMAGENS DIGITAIS
Authors: Milanez Fabrício , Silva Francisco Assis da , Cabral Flávio Pandur Albuquerque , Almeida Leandro Luiz de , Artero Almir Olivette , Piteri Marco Antônio
Published: January 2023

New technologies, such as 3D printers and autonomous cars for instance, originating from advances in Computer Vision and other fields, have been causing an increasingly high interest in robust pipelines for 3D reconstruction of real environments and objects. Through use of 3D reconstruction methods, it is possible to create an application that takes digital photographs of an observed scene as inputs and is capable of obtaining a 3D model that represents it. This model could then be used in a wide range of applications, such as game asset generation, video manipulation with special effects or object replication with the use of a 3D printer, for instance. In this paper, we address, present and discuss methods that concern the different stages of a traditional 3D reconstruction pipeline from digital images only in the implementation and use of computational tools that were capable of generating 3D models that represent a scene observed these images with high fidelity.
DETECÇÃO DE NUDEZ EM IMAGENS POR SEGMENTAÇÃO E RECONHECIMENTO DE PADRÕES
Authors: Oliveira Caique Cesar Gargel de , Almeida Leandro Luiz de , Silva Francisco Assis da , Siscoutto Robson Augusto
Published: January 2023

With the emergence of the INTERNET and the growth of social networks, the sharing of content, such as images, audios and videos, and access to this content through websites and social networks, has become much greater. Shared content, consisting of images, audio and/or videos, may not be appropriate for all audiences or environments, for various reasons. One of them is in relation to nudity and pornography, which is very present on the INTERNET and social networks, and can cause negative impacts when accessed in business environments, as well as it can cause problems in the development and behavior of children and adolescents. In order to control access to these types of content, it is necessary to develop resources that perform filtering. Therefore, this work seeks to contribute to the development of a tool capable of detecting nudity in images by combining existing image processing techniques, such as the detection of skin color pixels, counting of related elements, zoning techniques and nudity classifiers using machine learning algorithms. Tests carried out on showed an accuracy of 90.5% in the best case.
NANOFIBRAS DE POLI(ÁLCOOL VINÍLICO) COM ÓXIDO DE GRAFENO REDUZIDO PARA APLICAÇÃO EM SENSOR DE GÁS
Authors: Carvalho Beatriz Marques , Mingroni Vitor Hugo Uzeloto Fernandes , Silva André Antunes da , Silva Pedro Leonardo da , Olivati Clarissa de Almeida , Martins Lucas Michelão , Silva Filho Luiz Carlos da , Agostini Deuber Lincon da Silva
Published: January 2023

With the advancement of nanotechnology, nanomaterials such as nanofibers have gained attention, as they have applications in technological, environmental and health areas. In this context, electrospinning stands out for being considered a simple and versatile technique that allows the production of nanofibers. Carbon-based additives have been used to compose the polymeric matrix responsible for obtaining nanofibers, such as graphene, which among its applications has been used in gas sensors, as it can detect some molecules, including the ammonia. Thus, it is interesting to carry out studies of the polymer poly(vinyl alcohol) (PVA), together with the additive reduced graphene oxide (rGO), aiming at the application in ammonia gas sensor. Thus, electrospun PVA nanofibers with rGO were produced at different concentrations. To analyze the influence of rGO on PVA nanofibers, they were characterized by optical microscopy (OM) and tested in the presence of ammonia gas, generating graphs of current (i) by time (t). Therefore, electrospun nanofibers with considerable quantity and good formats were obtained, as seen in the OM images. By the graphs of i vs t, it was observed that the nanofibers that contained 4% of rGO showed greater sensitivity in the presence of ammonia gas, proving that rGO can be used as an additive in polymeric nanofibers with application in ammonia gas sensor.
CARACTERIZAÇÃO QUÍMICA DE BIOCARVÕES PRODUZIDOS A PARTIR DE BIOSSÓLIDO E BAGAÇO DE CANA-DE-AÇÚCAR
Authors: Souza Janardelly Gomes de , Alves Marcelo Rodrigo
Published: January 2023

The adequate characterization of solid residues is important, as it makes it possible to estimate the variability of its composition, helping to define its use in the soil. The objective of the presente study was to characterize raw materials and biochars produced under laboratory conditions, in order to analyze their feasibiity for use in the soil. Thus, the biochars were produced from the dry sample of biosolid and, from a dry sample of sugarcane bagasse, separately, by means of slow pyrolysis at a temperature of 350°C. A design with five replications was used, where the treatments were constituted by: pure biosolid (BP); pure sugarcane bagasse (BCP); biosolid biochar (BB); sugarcane bagasse biochar (BBC). The evaluation of raw materials and biochars was through immediate analysis, hydrogenion potential, electrical conductivity, organic matter, total nitrogen, cátion Exchange capacity, and X-ray fluorescence spectrometry. The data obtained in the characterization of the materials were submited to analysis of variance by the SISVAR program. To compare the means, the Tukey test was used program. To compare the means, the Tukey test was used at 5% probability (p<0.05). BP and BB had more alcaline pH, higher ash contente, higher nitrogen content and cátion Exchange capacity. While the BCP nd BBC showed higher values for organic matter and carbono. The raw materials and their respective biochars showed characteristics suitable for agricultural use, mainly BP and BB, and BP and BB can be used as soil correctors, as They have na alcaline pH of 12.02 and 9.64.
NANOPARTÍCULAS DE DIÓXIDO DE TITÂNIO E ÓXIDO DE ZINCO: SÍNTESE, CARACTERIZAÇÃO E AÇÃO FOTOCATALÍTICA EM EFLUENTES INDUSTRIAIS
Authors: Pavani Naiara Maria , Macena Daniel Ângelo , Tamashiro Jacqueline Roberta , Silva Lucas Henrique Pereira , Almeida Maryane Pipino Beraldo de , Kinoshita Angela Mitie Otta
Published: January 2023

The reuse of effluent water is one of the main challenges to achieve a more sustainable development. Dyes from the textile industry can percolate, contaminate soils and affect water courses. Advanced Oxidative Processes (AOP), such as heterogeneous photocatalysis with UV light radiation and metallic nanoparticles, generate reactive oxygen species and hydroxyl radicals that can reduce effluent pollutants. This work synthesized zinc oxide (ZnO-NP) and titanium dioxide (TiO2-NP) nanoparticles in order to photodegrade methylene blue and tartrazine yellow dyes. The crystallographic and morphological characterization of the nanoparticles was performed by X-ray diffraction and high resolution scanning electron microscopy. The syntheses produced nanometric particles. The methylene blue dye had greater degradation by TiO2-NP (82 to 85%), whereas the tartrazine yellow dye with ZnO-NP (79.6% removal). It is concluded that the nanoparticles combined with POA are an effective alternative for the photocatalytic degradation of dyes.
Scoping Review: Medical Education Interventions Optimizing Social Workers in the Emergency Department
Authors: Rehman Tehreem , Pidgeon Harrison , Chimileski Brock , Parker Shelby , Hsieh Dennis
Published: January 2023

Introduction: As the significance of social workers (SW) in improving healthcare delivery in the emergency department (ED) continues to expand, emergency physicians will increasingly be expected to effectively partner with SWs in both academic and community settings. In this scoping review we sought to provide evidence-based recommendations for effective emergency clinician educational interventions on how to incorporate SWs in the ED to address health-related social needs while also identifying directions for future research.

Methods: We conducted a systematic literature review of publications in PubMed, CINAHL, Cochrane Database of Systematic Reviews, Cochrane Central Register of Controlled Trials, and APA PsycINFO. A search strategy was designed in accordance with Peer Review of Electronic Search Strategies (PRESS) guidelines. Using the scoping review framework by Arksey and O’Malley, we applied consensus-based inclusion and exclusion criteria to guide study selection. A Preferred Reporting Items for Systemic Reviews and Meta-Analyses (PRISMA) flow chart delineating the selection process was generated using Covidence.

Results: Our search strategy identified nine qualifying articles for further analysis out of an initial sample of 2,119 articles. Of the nine articles that underwent full text review, 89% (8/9) evaluated a short educational didactic with or without a hands-on component to reinforce learning. Barriers to successful implementation of curricula discussed in all articles included time constraints, lack of buy-in from clinical faculty, lack of knowledge of appropriate referral sources once a problem is identified, and perceived distraction of the training from more standard clinical topics. Facilitators of curricula implementation and training success included the presence of a pre-existing and structured weekly conference schedule, ability to complete the training in a relatively short time frame or during intern orientation, presence of simulation resources, and residents’ overall perceived interest in the topics.

Conclusion: Ultimately, we found that interdisciplinary learning with SWs is generally well received by participants, and we offer various suggestions on incorporation into student and resident education. Moving forward, we recommend that a standardized curriculum of working with SWs be developed using didactic sessions, simulation, and/or direct observation with feedback.
Universal Precautions Plus: Physician-Directed Strategies for Improving Patient Health Literacy in the Emergency Department
Authors: Nwanaji-Enwerem Jamaji , Smith-Wilkerson Mikhaila , Gordon Brittney , Okpere Helene , Jones Terrell , Gizaw Rahel , Husain Irfan
Published: January 2023

Working on the frontlines with safety-net populations, emergency physicians are uniquely positioned to take on a greater role in addressing the current health literacy crisis and specific barriers that may exist. Here, we review the concept of universal health literacy precautions and explore the application of these universal precautions in conjunction with other patient-centered strategies. More specifically, to improve patient understanding and outcomes, emergency physicians can pair universal health literacy precautions with strategies including multiple learning techniques, dual-code theory, empowerment counseling, family buy-in, and hands-on practice. We provide two examples of emergency department encounters where this combined approach was used differently yet successfully and efficiently. Ultimately, we aim to highlight the value of emergency physicians being equipped with basic skills in health literacy educational strategies.
Simulation-based Mastery Learning Improves Emergency Medicine Residents’ Ability to Perform Temporary Transvenous Cardiac Pacing
Authors: Klein Matthew , Schmitz Zachary , Adler Mark , Salzman David
Published: January 2023

Introduction: Temporary transvenous cardiac pacing (TVP) is a critical intervention that emergency physicians perform infrequently in clinical practice. Prior simulation studies revealed that emergency medicine (EM) residents and board-certified emergency physicians perform TVP poorly during checklist-based assessments. Our objective in this report was to describe the design and implementation of a simulation-based mastery learning (SBML) curriculum and evaluate its impact on EM residents’ ability to perform TVP.

Methods: An expert panel of emergency physicians and cardiologists set a minimum passing standard (MPS) for a previously developed 30-item TVP checklist using the Mastery Angoff approach. Emergency medicine residents were assessed using this checklist and a high-fidelity TVP task trainer. Residents who did not meet the MPS during baseline testing viewed a procedure video and completed a 30-minute individual deliberate practice session before retesting. Residents who did not meet the MPS during initial post-testing completed additional deliberate practice and assessment until meeting or exceeding the MPS.

Results: The expert panel set an MPS of correctly performing 28 (93.3%) checklist items. Fifty-seven EM residents participated. Mean checklist scores improved from 13.4 (95% CI 11.8-15.0) during baseline testing to 27.5 (95% CI 26.9-28.1) during initial post-testing (P < 0.01). No residents met the MPS at baseline testing. The 21 (36.8%) residents who did not meet the MPS during initial post-testing all met or exceeded the MPS after completing one additional 30-minute deliberate practice session.

Conclusion: Emergency medicine residents demonstrated significantly improved TVP performance with reduced variability in checklist scores after completing a simulation-based mastery learning curriculum.
Incorporation of a Case-based Health Equity Curriculum into Morbidity and Mortality Conference
Authors: Carreras Tartak Jossie , Rodriguez Giovanni , Goralnick Eric , Macias-Konstantopoulos Wendy , Egan Daniel
Published: January 2023

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