bluuebunny/crossref_metadata_2025 huggingface dataset:
An injectable, in situ forming and NIR-responsive hydrogel persistently reshaping tumor microenvironment for efficient melanoma therapy
Authors: Zhang Han , Hu Liangshan , Xiao Wei , Su Yanqiong , Cao Donglin
Published: November 2023

Background

Melanoma is a highly aggressive form of skin cancer with increasing incidence and mortality rates. Chemotherapy, the primary treatment for melanoma, is limited by hypoxia-induced drug resistance and suppressed immune response at the tumor site. Modulating the tumor microenvironment (TME) to alleviate hypoxia and enhance immune response has shown promise in improving chemotherapy outcomes.

Methods

In this study, a novel injectable and in situ forming hydrogel named MD@SA was developed using manganese dioxide (MnO
2
) nanosheets pre-loaded with the chemotherapy drug doxorubicin (DOX) and mixed with sodium alginate (SA). The sustainable drug delivery, oxygen generation ability, and photothermal property of MD@SA hydrogel were characterized. The therapeutic efficacy of hydrogel was studied in B16F10 in vitro and B16F10 tumor-bearing mice in vivo. The immune effects on macrophages were analyzed by flow cytometry, real-time quantitative reverse transcription PCR, and immunofluorescence analyses.

Results

The MD@SA hydrogel catalyzed the tumoral hydrogen peroxide (H
2
O
2
) into oxygen, reducing the hypoxic TME, down-regulating hypoxia-inducible factor-1 alpha (HIF-1α) and drug efflux pump P-glycoprotein (P-gp). The improved TME conditions enhanced the uptake of DOX by melanoma cells, enhancing its efficacy and facilitating the release of tumor antigens. Upon NIR irradiation, the photothermal effect of the hydrogel induced tumor apoptosis to expose more tumor antigens, thus re-educating the M2 type macrophage into the M1 phenotype. Consequently, the MD@SA hydrogel proposes an ability to constantly reverse the hypoxic and immune-inhibited TME, which eventually restrains cancer proliferation.

Conclusion

The injectable and in situ forming MD@SA hydrogel represents a promising strategy for reshaping the TME in melanoma treatment. By elevating oxygen levels and activating the immune response, this hydrogel offers a synergistic approach for TME regulation nanomedicine.
Mechanisms of Ovarian Cancer-Associated Cachexia
Authors: Callaway Chandler S , Mouchantat Lila M , Bitler Benjamin G , Bonetto Andrea
Published: November 2023

Cancer-associated cachexia occurs in 50% to 80% of cancer patients and is responsible for 20% to 30% of cancer-related deaths. Cachexia limits survival and treatment outcomes, and is a major contributor to morbidity and mortality during cancer. Ovarian cancer is one of the leading causes of cancer-related deaths in women, and recent studies have begun to highlight the prevalence and clinical impact of cachexia in this population. Here, we review the existing understanding of cachexia pathophysiology and summarize relevant studies assessing ovarian cancer–associated cachexia in clinical and preclinical studies. In clinical studies, there is increased evidence that reduced skeletal muscle mass and quality associate with worse outcomes in subjects with ovarian cancer. Mouse models of ovarian cancer display cachexia, often characterized by muscle and fat wasting alongside inflammation, although they remain underexplored relative to other cachexia-associated cancer types. Certain soluble factors have been identified and successfully targeted in these models, providing novel therapeutic targets for mitigating cachexia during ovarian cancer. However, given the relatively low number of studies, the translational relevance of these findings is yet to be determined and requires more research. Overall, our current understanding of ovarian cancer–associated cachexia is insufficient and this review highlights the need for future research specifically aimed at exploring mechanisms of ovarian cancer–associated cachexia by using unbiased approaches and animal models representative of the clinical landscape of ovarian cancer.
Οι εννοιακές μεταφορές στα Ομηρικά Έπη
Authors: Λαζάκη Παναγιώτα
Published: November 2023

Σε αντίθεση με την παραδοσιακή θεώρηση της μεταφοράς, η Γνωσιακή Γλωσσολογία προσεγγίζει τις μεταφορές όχι μόνο ως γλωσσικές εκφράσεις αλλά και ως τρόπο σκέψης που καθιστά δυνατή τη σύλληψη αφηρημένων φαινομένων μέσω της συσχέτισής τους με απτές εμπειρίες, ώστε να αναδειχτεί ο πρωταρχικός ρόλος της στη δόμηση του ανθρώπινου αντιληπτικού συστήματος και η διάχυτη παρουσία της στην καθημερινή γλωσσική πρακτική. Στόχος της παρούσας διατριβής είναι ο εντοπισμός των εννοιακών μεταφορών στα Ομηρικά Έπη και ειδικότερα στην Τηλεμάχεια της Οδύσσειας (ραψωδίες α-δ) υπό το θεωρητικό πρίσμα της Θεωρίας της Εννοιακής Μεταφοράς (ΘΕΜ στο εξής, Conceptual Metaphor Theory, CMT), όπως αυτό διατυπώθηκε κυρίως από τους Lakoff & Johnson (1980) και αναπτύχθηκε/εμπλουτίστηκε από τον Kövecses (2002) και η καταγραφή τους σε μια βάση δεδομένων που να μπορεί να αξιοποιηθεί εν συνεχεία ως σώμα κειμένων για ερευνητικούς σκοπούς. Τέθηκαν τρία ερευνητικά ερωτήματα α) ποιο είναι το συχνότερο είδος εννοιακής μεταφοράς στην Τηλεμάχεια στο πρωτότυπο και στη μετάφραση, β) ποιες είναι οι συχνότερες εννοιακές μεταφορές ανά ραψωδία και ποια είναι συνολικά η πιο συχνόχρηστη στην Τηλεμάχεια της Οδύσσειας του Ομήρου και γ) ποιες είναι οι στρατηγικές μετάφρασης στη νέα ελληνική των εννοιακών μεταφορών της Τηλεμάχειας. Για την ανάλυση δεδομένων χρησιμοποιήθηκε η επαγωγική μέθοδος προσέγγισης των μεταφορών. Η ανάλυση του σώματος δεδομένων ανέδειξε ότι α) τόσο στο ομηρικό κείμενο όσο και στη νεοελληνική απόδοσή του υπερισχύουν οι οντολογικές μεταφορές, β) οι συχνότερες εννοιακές μεταφορές που εντοπίστηκαν αφορούν τον Χρόνο, το Μυαλό/Νόηση, τον Λόγο, τον Οίκο/Περιουσία, τον Αντίπαλο και το Συνειδητό/Ασυνείδητο, ενώ η πιο συχνόχρηστη εννοιακή μεταφορά είναι εκείνη που αφορά στην εννοιοποίηση λέξεων/εννοιών που ανήκουν στην ομάδα του όρου ‘θυμός’ και αφορούν την έννοια του ΜΥΑΛΟΥ και της ΝΟΗΣΗΣ και ότι γ) πολλές από τις εννοιακές μεταφορές του ομηρικού κειμένου είναι παρούσες στη νεοελληνική μετάφραση. Η πρωτοτυπία της έρευνας έγκειται στην εισαγωγή νέων ερευνητικών ερωτημάτων, που μας επιτρέπουν να προσεγγίσουμε τον ομηρικό άνθρωπο, στη συστηματική καταγραφή των εννοιακών μεταφορών στην Τηλεμάχεια και στη συγκρότηση συστηματικής μεθοδολογίας για τη μελέτη της εννοιακής μεταφοράς στον Όμηρο.
Συμβολή στη μελέτη της γεωγραφίας της Κύπρου τον 19ο αιώνα μέσα από την ανάλυση ιστορικών χαρτών και άλλων τεκμηρίων με σύγχρονα εργαλεία και μεθόδους γεωπληροφορικής
Authors: Παπαδιάς Ευάγγελος
Published: November 2023

Δίχως αμφιβολία, η κοινωνία, ο σύγχρονος πολιτισμός και κατ’ επέκταση και ο ακαδημαϊκός χώρος και τα επιστημονικά πεδία, αντιμετωπίζουν έναν μεγάλο και σε πολλές περιπτώσεις ραγδαίο μετασχηματισμό. Η ψηφιακή γνώση, οι ψηφιακές διαδικασίες ανάλυσης, παρουσίασης, διδασκαλίας, μεθοδολογίας κλπ., υιοθετούνται ολοένα και περισσότερο, άλλες φορές άκριτα και άλλες με έντονο σκεπτικισμό. Τα Συστήματα Ιστορικής Γεωγραφικής Πληροφορίας (Historical GIS) είναι ένα αναδυόμενο εργαλείο έρευνας των τελευταίων δεκαετιών, το οποίο τυγχάνει σχετικά περιορισμένης αποδοχής από τις Ανθρωπιστικές επιστήμες. Στην παρούσα διατριβή γίνεται σύνθεση ιστορικών γεωγραφικών πληροφοριών, διαφορετικής μορφής και από διαφορετικές πηγές, με σκοπό τη μελέτη της εξέλιξης στοιχείων του τοπίου της Κύπρου, αξιοποιώντας ιστορικούς χάρτες, περιγραφές περιηγητών, ιστορικά δεδομένα απογραφών και άλλες αναπαραστάσεις του χώρου, από τις αρχές της Οθωμανικής περιόδου (1571) μέχρι και πριν την Τουρκική εισβολή (1969). Επίκεντρο ενδιαφέροντος αποτελεί ο 19ος αιώνας και βασικό ιστορικό τεκμήριο μελέτης, ο εμβληματικός για τη χαρτογραφία του νησιού χάρτης του Horatio Herbert Kitchener, έκδοσης 1885. Χρησιμοποιώντας μεθόδους και τεχνικές της Επιστήμης Γεωγραφικής Πληροφορίας, αναζητούνται χωρικά πρότυπα και εξετάζεται η συμβολή αλλά και τα μειονεκτήματα των Συστημάτων Ιστορικής Γεωγραφικής Πληροφορίας, ως εργαλείου έρευνας στις επιστήμες του ανθρώπου και πιο συγκεκριμένα στην ιστορική έρευνα. Η διατριβή επιχειρεί να συμβάλλει στην κατανόηση της Γεωγραφίας της Κύπρου τον 19ο αιώνα, εστιάζοντας στον πληθυσμό, τους οικισμούς, στην κάλυψη γης, στις βασικές αγροτικές δραστηριότητες και στα δίκτυα μεταφοράς και επικοινωνίας. Παράλληλα, γίνεται κριτική αξιολόγηση των στοιχείων που αποτυπώνονται στο χάρτη του H.H. Kitchener και αποτέλεσαν αντικείμενο της εμπειρικής ανάλυσης. Από τη διερεύνηση, αναδεικνύεται η σπουδαιότητα της μελέτης των ιστορικών τοπωνυμίων, που αποτελεί το θεμέλιο λίθο για την αξιοποίηση οποιουδήποτε ιστορικού τεκμηρίου. Η οργάνωση σύγχρονων γεωγραφικών ευρετηρίων (gazetteers) αποτελεί τη βάση για την περαιτέρω ανάπτυξη των Συστημάτων Ιστορικών Γεωγραφικών Πληροφοριών. Ιδιαίτερα για την Κύπρο, η μελέτη των τοπωνυμίων είναι υψηλής πολιτισμικής αξίας.
Działalność edukacyjna i popularyzatorska archiwów archidiecezjalnych i diecezjalnych w Polsce. Rekonesans badawczy
Authors: Mazur Hubert Michał
Published: November 2023

Celem artykułu jest próba odpowiedzi, czy działania edukacyjne i popularyzatorskie są obecne w archiwach archidiecezjalnych i diecezjalnych Kościoła rzymskokatolickiego w Polsce. Podstawą rozważań jest zawartość portali internetowych wspomnianych placówek oraz kwestionariusze ankiet wypełnione i nadesłane przez personel archiwów. Z przeprowadzonych badań wynika, że zaledwie kilka archiwów archidiecezjalnych i diecezjalnych podejmuje aktywność na niwie edukacji i popularyzacji. Do głównych jej form należą wystawy organizowane przez niektóre archiwa, a częściej współorganizowane z innymi podmiotami. Archiwa archidiecezjalne i diecezjalne przyjmują także wycieczki uczniów, studentów, doktorantów, członków wspólnot i stowarzyszeń katolickich, umożliwiając im zwiedzanie swoich siedzib. Przy okazji dla zwiedzających wygłaszane są odczyty i prelekcje o tematyce archiwalnej i historycznej.
Increasing learning outcomes for citizenship education courses based on google applications at PGSD FIP UMJ in 2022
Authors: Santoso Gunawan , Abdulkarim Aim , Maftuh Bunyamin , Sapriya Sapriya , Murod Ma'mun Murod , Retnasari Lisa Retnasari
Published: November 2023

A good citizen is, of course, greatly influenced by the national ideology of each country. Citizenship Education (CE), whose mission is to make citizens who are smart, good, and democratic citizens through nationalistic, patriotic, professional, and scientific behavior, This study aims to determine the contribution of pedagogic competence and professional competence to learning outcomes. This study uses a classroom action research (PTK) approach. The research population was PGSD FIP UMJ students. Research data were collected using a questionnaire, and the results were analyzed using regression analysis. The results showed that: (1) there is a significant relationship between pedagogic competence and learning outcomes in the effective category; (2) there is a significant and positive relationship between professional competence and learning outcomes. (3) There is a significant and positive relationship between the effectiveness of pedagogical competence and professionalism simultaneously on student civic learning outcomes. The results have provided valuable experience about the benefits of Google technology-based applications such as Meet, Google form, Classroom, Breakout Rooms, Jamboard, recording, Drive, Docs, Gmail, and whiteboarding for students of the PGSD FIP Study Program, University of Muhammadiyah Jakarta in 2022, according to 88% of the students. For obstacles in the jamboard application, the best resolution that is effective and efficient according to existing conditions is to provide repeated socialization, training, and evaluation monitoring to several students who have no experience in sophistication Google application-based Meet, Google form, Classroom, Breakout Rooms, Jamboard, recording, Drive, Docs, Gmail, and whiteboarding.
Guiding with wisdom: a model for early childhood sexual education classroom management
Authors: Nofridasari Erlita Ayu , Hasanah Enung
Published: November 2023

Effective sex education plays a crucial role in providing children with a healthy understanding of sexuality, yet there persist various issues related to sex education in kindergarten. Classroom management challenges also represent significant obstacles that need to be addressed for the successful implementation of sex education. Within educational institutions like Ceria Timoho Kindergarten, the role of teachers in delivering sex education remains pivotal. This research aims to identify classroom management patterns used in providing sex education to children at Ceria Timoho Kindergarten through a qualitative approach involving observation, documentation, and interviews. Data analysis employed qualitative analysis methods. The research results reveal that the classroom management model for sex education emphasizes student-centric approaches that consider individual needs, holistic strategies encompassing emotional, social, and ethical aspects, the selection of age-appropriate teaching methods, the importance of effective communication, and the necessity for thorough evaluation to ensure age-appropriate understanding. These findings offer valuable insights into the significance of effective sex education in helping children comprehend and respect their sexuality, fostering emotional and physical awareness, and promoting overall well-being.
The tendency of persuasive messages in Instagram captions @tacobellid period March – August 2023
Authors: Tsany Fadli Ammar , Junaedi Fajar
Published: November 2023

Taco Bell is a fast food brand still very new in Indonesia. The arrival of Taco Bell in Indonesia, which is very late, is a challenge to compete with other fast food giants. This challenge is no exception in managing social media, especially Instagram. This quantitative research examines the tendency of persuasive messages in the captions of posts from the Instagram account @tacobellid, a promotional medium for the Taco Bell Indonesia brand. This research uses a quantitative content analysis method on 149 post captions uploaded by @tacobellid in March-August 2023. The persuasive messages analyzed are captions with the category of compelling message requirements. The structure of a persuasive message includes message-sidedness, order of presentation, conclusion drawing, and how to convey a persuasive message. The results of this research show that of the 149 captions during March - August 2023, there were 114 captions containing persuasive messages, with the most detailed categories of persuasive message requirements containing the interests of the sender and recipient of the message, there were 61 captions with a percentage of 54%, the highest message sidedness category was two-sided, there are 92 captions with a percentage of 81%, the highest order of presentation category is primary, there are 71 captions with a percentage of 62%, the highest category for conclusion drawing is explicit, there are 100 captions with a percentage of 88%, and the category for how to convey the most persuasive messages is emotional appeal. There are 42 captions with a percentage of 37%. These findings show that the Taco Bell Instagram account is trying to attract audience awareness by providing a tendency towards a two-sided message structure that displays the emotional side so the audience can accept the messages.
The role of art director in film artistic style before, now & then (Nana) fourcolors film production
Authors: Ramadlan Tegar Jihad , Muttaqien Muhammad
Published: November 2023

"Before, Now & Then (Nana)" is the first Sundanese language movie in Indonesia. The film won the best artistic director award at the Indonesian Film Festival (FFI). The movie has a setting in West Java around the 1960s which is adapted from the Autobiographical novel Jais Darga Namauku by Ahda Imran. This research aims to identify the role of art director in the artistic layout of the film "Before, Now & Then (Nana)". The method used in this research is descriptive qualitative. Data collection techniques include interviews and documentation. This research uses three stages in analyzing data, namely data reduction, data presentation and conclusion drawing. In testing the validity of the data, researchers used source triangulation which means comparing rechecking data from more than one source to ensure whether the data is correct or not. The results of this study indicate that in creating a setting (setting, costumes, makeup and lighting) of course there are things that are done by artistic stylists in the pre-production to post production stages. In the pre-production stage, the art director is responsible for the creative design aspect, designing the overall artistic concept of the movie. At the production stage the art director is responsible for all the sets or properties used. In the post-production stage, the art director evaluates all divisions within the artistic department. It can be concluded that the role of the artistic stylist or art director in this film plays an important role in building the 60s era in the film so that it can influence the truth or belief in the eyes of the audience through the artistic layout created.
Content analysis of the moral message of Grab ads edition “Naik Grab, gak ada kata telat buat kejar apa aja”
Authors: Simorangkir Aidil Akbar , Anisa Eka
Published: November 2023

Grab is an online transportation service company that uses YouTube as a promotional medium with one of its advertisements edition "Naik Grab, Gak Ada Kata Telat Buat Kejar Apa Aja". Grab ads do not directly only offer its products, but Grab displays advertisements with a series of life stories that are closely related to people's lives. This study aims to find out the moral message in Grab advertisements. This research is a qualitative content analysis research. The data used is Grab's 2023 edition of the "Naik Grab, Gak Ada Kata Telat Buat Kejar Apa Aja" edition downloaded from YouTube. Data collection techniques are carried out by observation, documentation and literature study. Data analysis techniques in this study include data reduction, data presentation and data verification. Then from the results of the analysis, researchers get various moral messages contained in Grab advertisements. The results showed that the Grab ad edition "Naik Grab, Gak Ada Kata Telat Buat Kejar Apa Aja" conveys moral messages including the first individual moral message consisting of hard work, optimism, and responsibility. The second is social morals or human relations with the social environment, namely affection. In advertising, Grab as a whole is more likely to convey an individual's moral message or human relationship with oneself.
Event and experience of Cherrypop 2023 as a multigenre music festival in Yogyakarta
Authors: Saidah Najmi , Sudiwijaya Erwan , Aulia Aly
Published: November 2023

Music festival is a prevalent activity with many people as a tool to communicate information through music by having various cultural forms, social interactions, and experiences at an event. This study aims to describe the event and experience strategies carried out by Cherrypop 2023 as an event with a creative arena with a youth sub-cultural ecosystem to correspond with each other, build discourse, and celebrate through a multi-genre music festival experience. The method used in this study is a qualitative method with descriptive analysis methods. The data is collected through literature and field studies (interviews, observation, and documentation). The results of this study show that Cherrypop conducts research before carrying out the event, designs related to creative ideas such as brainstorming and mind mapping, the planning process that involves the use of the laws of time, space, and tempo, coordination with communication efforts to cooperate with internal and external parties, and evaluation of all divisions to analyze whether the event was successful or not and correct mistakes this year in order to be better for future events. These essential steps made it easier for Cherrypop to realize the event and provide the experience that they wanted to achieve.
User perceptions of the TikTok shop application for selling
Authors: Fauzan Ade Muhammad , Sumarlan Iman
Published: November 2023

TikTok has integrated e-commerce features through TikTok Shop, enabling users to sell products online. This research aims to explore user perceptions of TikTok Shop as a tool for selling. The research employs a qualitative approach, collecting data through interviews with three active TikTok Shop users engaged in selling. Data analysis is conducted using descriptive analysis. This study will delve into various aspects of user perceptions of TikTok Shop, including ease of use, reliability, challenges, and risks associated with selling on this platform. The research findings indicate that TikTok Shop has garnered positive appreciation from merchants due to its user-friendly interface and responsive technical support. The simple interface facilitates product management and promotions, while features such as trade statistics enrich interactions with customers. This suggests that TikTok Shop is effective in supporting online selling, making it a smart choice for merchants seeking efficient business operations. Reliability is also a critical factor in building trust among merchants regarding the platform. Secure payment systems instill confidence in the safety of online transactions, and the rarity of disruptions or downtime underscores the quality of technical infrastructure that supports smooth selling. The lengthy, trouble-free experiences of merchants further reinforce the positive view of the platform's reliability. However, merchants also face certain challenges and risks when selling on TikTok Shop. Fierce competition, algorithm changes, and the need for more comprehensive guidance are common challenges that merchants must address. Risks related to data security and the need to understand and manage customer data are also significant concerns.
Development strategies of Tanjung tourist village to enhance tourist visits
Authors: Ananda Destrya , Hakim Lukman
Published: November 2023

Tanjung Tourist Village, located in Donoharjo Village, Ngaklik District, Sleman Regency, Special Region of Yogyakarta, is a cultural tourism destination that highlights the lives of farmers who strongly uphold Javanese cultural values. Unfortunately, Tanjung Tourist Village has experienced slow development, and some of its annual activities have been hindered. This research aims to formulate development strategies for Tanjung Tourist Village to increase tourist visits and identify supporting and inhibiting factors in the development efforts. The research focuses on qualitative aspects with a descriptive approach. The research was conducted in Tanjung Tourist Village, Sleman, DIY, in October 2023. Data was collected through interviews, documentation, and observations, and then analyzed qualitatively through data reduction, data presentation, and drawing conclusions. The results of the research show that supporting factors for the development of Tanjung Tourist Village include natural beauty, good accessibility, adequate facilities, friendly community service, and financial support from the Sleman Local Government. On the other hand, there are inhibiting factors such as poorly organized facilities, a lack of trained human resources in tourism management, and competition with neighboring tourist villages. Development strategies involve the inventory of tourism assets, mapping of community resources, strong promotion, participatory program planning, implementation as planned, transparent financial control, periodic evaluation, and document archiving. With well-planned steps, it is expected that Tanjung Tourist Village can optimize its tourism potential, improve the welfare of the community, and become an attractive destination for tourists.
Followers' motives of Muhammadiyah University of Yogyakarta student on the Instagram account @dear_umycatcallers
Authors: Putratama Argo Raihan , Suciati Suciati
Published: November 2023

Instagram is a social media platform that functions to share photos, videos, and information. An Instagram account called @dear_umycatcallers which is managed by gender and sexuality activists in Yogyakarta was widely discussed by students at Muhammadiyah University of Yogyakarta in early 2022. The Instagram account @dear_umycatcallers is an account that provides information about education and complaints of sexual violence around the Muhammadiyah University of Yogyakarta in every upload. Currently, the Instagram account @dear_umycatcallers has more than 9,000 followers. This research was conducted to determine the motives of followers of Muhammadiyah University Yogyakarta students on the Instagram account @dear_umycatcallers. Researchers used qualitative research methods with in-depth interview data collection techniques with 7 informants. The technique for taking informants uses an accidental sampling technique. The data analysis uses interactive analysis, with data validity testing using source triangulation. The theory used in this research is Herbert Blumer's motive theory with descriptive qualitative data analysis techniques. The research results show that for information motives, uploads from the Instagram account @dear_umycatcallers regarding cases of sexual violence that occurred within the Muhammadiyah University of Yogyakarta are an important issue that is needed by followers. This information is needed by followers who are also students at Yogyakarta Muhammadiyah University so that they can increase their knowledge and awareness to avoid sexual violence. Regarding personal identity motives, the majority of informants commented and shared uploads from the Instagram account @dear_umycatcallers regarding sexual violence with their friends. This is done as a form of caring for the people around them in their ways. Regarding the diversion motive, the majority of informants felt entertained when they saw other people's comments in the comments column in the Instagram account upload @dear_umycatcallers.
Qualitative content analysis of racism in the film Kamen Rider black sun
Authors: Hatmojo Panji Tri
Published: November 2023

Racism is a form of discrimination carried out by race majority to race minority. Racism is a big issue that never stops in this world until now. Many minority races keep struggling due to these issues and trying to get their right. The Kamen Rider Black Sun film is a Japanese superhero film series that brings up the theme issue of racism. Directed by Kazuya Shiraishi, released on October 28, 2022, via the Prime Video online streaming platform, it tells a story about the chaos that occurred between humans and a humanoid monster called Kaijn which actually mysteriously appeared in Japan 50 years ago. The existence of Kaijin brings up two strongholds on humans who hate and want to destroy the existence of Kaijin and those who think that Kaijin can live side by side in a way of peace with humans.To know How Racism in the Kamen Rider Black Sun film, this research uses method qualitative descriptive with technique content analysis. Based on the results of the study, it can be concluded that emerging racism in the film Kamen Rider Black Sun is divided become two namely: First, personal racism consisting of behavior, beliefs, and actions indicating race in the film. Second, institutional racism refers to actions condescending to race and certain things to do by social institutions and government.
Exploitation of women’s bodies in variety programs show D’café at Trans 7
Authors: Fitriyanto Dwi , Nur Fitrinanda An
Published: November 2023

As time goes by, mass media has become a need that is almost inseparable from humans, one of which is television. Television has now become a means of entertainment for some people, many TV stations are competing to create programs to meet the entertainment needs of their viewers, not infrequently many violations are still broadcast in order to pursue TV program ratings, one of which is the exploitation of women. This research was made based on the many cases of exploitation of women's bodies that occurred in mass media such as television, especially the reality show program 'D'café' trans 7. Seeing this problem, the formulation of the problem in this research is; how women's bodies are exploited on the variety show program D'café on July 1 2021. This research aims to find out cases of exploitation of women, especially in the variety show program D'café trans 7. This research uses a qualitative content analysis method where researchers use data such as images from this verit show program to strengthen the results of this research. In this research, researchers used commodification theory. In the D'café broadcast on July 1 2021, Aspiration and Doctor Boyke were invited with a chat topic about sexual fantasies. The results of this research confirm that the beauty of women's bodies has always been used as a commodity capable of accumulating capital or generating profits. Because women are a very large market in the media industry which is believed to be able to attract many viewers to generate high ratings.
The influence of Instagram @Warunk_upnormal social media marketing communication strategy in marketing products on consumer buying interest
Authors: Sagita Intan
Published: November 2023

In business world, the use of social media to market products already sounds familiar. Social media is used as a practical liaison tool between business people and customers, without having to think about time and location. One of the many culinary businesses that implement promotional strategies using social media, especially Instagram. Warunk Upnormal is a company that actively offers and introduces their products through social media. Promotions carried out through Instagram have more advantages because social media has a wide reach coupled with 423,000 Instagram account followers which makes the account quite known to potential consumers. This research was conducted in generalization with a focus on followers who have an active character in using Instagram media and following @warunk_upnormal accounts. Then the observations made in this study used questionnaires as direct observations of objects. Based on the influence of variable X (Social Media Influence) and variable Y (Buying Interest) based on the results of the coefficient of determination has an influence of 18.8%, while 82.1% is influenced by other factors outside this study. From the results of a simple linear regression test with the results of the regression coefficient having a positive value, it can be stated if there is an influence between the independent variable and the dependent variable. It can be concluded that the influence of Warunk Upnormal Instagram social media has an influence on consumer buying interest.
Informal carers, part 5: their roles and support needs
Authors: Barber Chris
Published: November 2023

This series is exploring the definition, meaning and roles of informal caring and informal carers, statistics and lived experiences regarding informal caring, the law and Government strategies regarding informal caring and the role of the registered nurse (RN), nursing associate (NA) and healthcare assistant (HCA) in supporting the informal carer. This fifth article will briefly explore the lived experiences of informal carers and how HCAs, NAs and nurses could support informal carers.
Comparison between multiple logistic regression and machine learning methods in prediction of abnormal thallium scans in type 2 diabetes
Authors: Yang Chung-Chi , Peng Chung-Hsin , Huang Li-Ying , Chen Fang Yu , Kuo Chun-Heng , Wu Chung-Ze , Hsia Te-Lin , Lin Chung-Yu
Published: November 2023

BACKGROUND

The prevalence of type 2 diabetes (T2D) has been increasing dramatically in recent decades, and 47.5% of T2D patients will die of cardiovascular disease. Thallium-201 myocardial perfusion scan (MPS) is a precise and non-invasive method to detect coronary artery disease (CAD). Most previous studies used traditional logistic regression (LGR) to evaluate the risks for abnormal CAD. Rapidly developing machine learning (Mach-L) techniques could potentially outperform LGR in capturing non-linear relationships.

AIM

To aims were: (1) Compare the accuracy of Mach-L methods and LGR; and (2) Found the most important factors for abnormal TMPS.

METHODS

556 T2D were enrolled in the study (287 men and 269 women). Demographic and biochemistry data were used as independent variables and the sum of stressed score derived from MPS scan was the dependent variable. Subjects with a MPS score ≥ 9 were defined as abnormal. In addition to traditional LGR, classification and regression tree (CART), random forest, Naïve Bayes, and eXtreme gradient boosting were also applied. Sensitivity, specificity, accuracy and area under the receiver operation curve were used to evaluate the respective accuracy of LGR and Mach-L methods.

RESULTS

Except for CART, the other Mach-L methods outperformed LGR, with gender, body mass index, age, low-density lipoprotein cholesterol, glycated hemoglobin and smoking emerging as the most important factors to predict abnormal MPS.

CONCLUSION

Four Mach-L methods are found to outperform LGR in predicting abnormal TMPS in Chinese T2D, with the most important risk factors being gender, body mass index, age, low-density lipoprotein cholesterol, glycated hemoglobin and smoking.
Granular cell tumor of the breast: A case report and review of literature
Authors: Yan Jun
Published: November 2023

BACKGROUND

Granular cell tumor (GCT) of the breast (GCTB) is a rare neoplasm that can exhibit malignant characteristics both clinically and radiologically. This tumor can also coexist and colocalize with breast carcinoma.

CASE SUMMARY

We present a patient with this uncommon tumor and discuss the diagnostic and therapeutic approaches in order to further the knowledge of GCTB and prevent misdiagnosis and overtreatment. The characteristics of the tumor, methods of diagnosis, therapy and postoperative pathological outcomes were analyzed, and relevant literatures of GCTs were reviewed. The patient underwent surgery after core needle biopsy, and the excised neoplasm was sent for pathological examination. Histological analysis revealed nests of cells with abundant pink granular cytoplasm, confirming the diagnosis of GCTB.

CONCLUSION

As manifestations of GCT and malignancy can mimic each other, a careful histological examination is essential before major surgery. Treatment consisting of complete excision with close clinical follow-up is recommended.
Successful leadless pacemaker implantation in a patient with dextroversion of the heart: A case report
Authors: Li Na , Wang Hai-Xiong , Sun Yue-Hui , Shu Yan
Published: November 2023

BACKGROUND

Dextroversion is defined as the presence of dextrocardia with situs solitus, dextro-loop ventricles, and normally related great arteries. Dextrocardia can pose technical challenges when interventional treatments are required. However, the challenges posed by dextroversion can be amplified due to the disruption of typical anatomical relationships, the unpredictable positioning and boundaries of cardiac structures resulting from the shift, and the pathological processes influencing rotation.

CASE SUMMARY

A 73-year-old woman with cardiac dextroversion suffered from a recurrence of atrial fibrillation after her radiofrequency catheter ablation and Despite the cessation of antiarrhythmic medications, there were episodes of sinus pauses and symptomatic bradycardia, with heart rates dropping as low as 28 beats per minute.

CONCLUSION

Dextroversion makes the implantation of leadless pacemakers more challenging, and appropriate adjustments in fluoroscope angles may be crucial for intracardiac operations. Additionally, when advancing delivery systems, attention should be paid to rotational direction during valve-crossing procedures; changes in the perspective of posture angle between normal cardiac position and dextroversion can serve as references.
Pengelompokan Kabupaten/Kota di Provinsi Jawa Barat Berdasarkan Dampak Kerusakan Bencana Banjir Menggunakan K-Medoids
Authors: Gustiara Dela , Mulyaningsih Anisa Dwi , Anadra Rahmi , Widodo Edy
Published: November 2023

The territory of Indonesia is located in geographical, geological, hydrological, and demographic conditions that allow Indonesia to be prone to disasters. The most common natural disaster in Indonesia is flooding. If accumulated, there have been 682 flood events in the country since the beginning of 2022. In Indonesia, especially West Java Province, flooding is the most common disaster, especially during the rainy season. So a study will be conducted that aims to determine the grouping of districts / cities in West Java Province based on the occurrence of flood disasters. The data used in this study were obtained from the publication of the National Disaster Management Agency. In this study, there are 4 variables of the impact of flood disasters, namely total deaths, total submerged houses, total damaged houses and total injured. The clustering method used in this research is K-Medoids. K-Medoids is one of the clustering methods that uses the partition clustering method in grouping a set of n objects into a number of k clusters. From the results of the K-Medoids analysis, three clusters were obtained. The first cluster consists of 3 districts/cities with high impact of flood disasters, the second cluster consists of 23 districts/cities with moderate impact of flood disasters, and the third cluster consists of 1 district/city with low impact of flood disasters. Based on the results of the analysis, efforts can be made by the government to focus more on designing steps that must be taken in preventing or overcoming the impact of flood disasters.

Keywords: Cluster; K-Medoids; Floods West Java
Gender and repression in an autocracy: findings from Belarus
Authors: Nikolayenko Olena
Published: November 2023

A growing body of research recognizes the impact of gender on social movement activity. Yet, far less attention has focused on the deployment of repressive methods in a gendered manner. The study contributes to comparative politics literature by proposing a typology of repression. At the start of mass mobilization, state authorities tend to invoke patriarchal norms to ridicule and stigmatize activists. Next, the coercive apparatus targets protesters through the use of psychological intimidation, physical violence, and sexual violence, as well as legal and economic repression. At the end of protests, the police resort to debasement and dehumanization of jailed protesters in a gendered manner. Drawing on the case of Belarus, one of the most restrictive political regimes in Europe, the study illustrates how repressive methods are gendered throughout different phases of mass mobilization. The study seeks to expand our understanding of various ways in which individuals are subject to repression.
Iconicity Perception under the Lens of Iconicity Rating and Transparency Tasks in Israeli Sign Language (ISL)
Authors: Fuks Orit
Published: November 2023

Abstract: This study undertook iconicity ratings and conducted transparency experiments on Israeli Sign Language (ISL). Experiment 1 compared the iconicity ratings of 520 lexical signs of ten Deaf ISL signers and thirteen hearing nonsigners. Ratings were found to be affected by language knowledge, lexical class, and type of iconic mapping, as well as by factors less connected to iconicity, such as a sense of familiarity with a form. In experiment 2, twenty nonsigners guessed the meaning of the 520 signs, and the correct guesses were correlated with the iconicity scores. Overall, nonsigners tended to interpret signs as representing actions. The results demonstrated that (1) signers' ratings reflect the diverse semiotic ways that meanings are represented in the lexicon, predictably more so than nonsigners' ratings, and (2) when meanings are not provided, the perception of iconicity is attuned mostly to the movement aspect of the forms. It is recommended that both studies be conducted together in order to achieve a more nuanced picture concerning the perception of iconicity and its role in the lexicon.
Courtesans, Consorts, Poetesses, Avadhāninī s, and Śatalekhinī s: The Multitalented Female Artists at the Seventeenth-Century Nāyaka Court in Tanjore
Authors: Cielas Hermina
Published: November 2023

ABSTRACT: This essay aims to compare the work of Rāmabhadrāmbā, Madhuravāṇī, Raṅgājamma, and Kṛṣṇājī, Indian performative artist-courtesans and poetesses active in the seventeenth century at the Nāyaka court in Tanjore. The paper seeks to expand knowledge about them and their work, a significant subject that has been underresearched in Indology so far. The skills and literary achievements of female artists are presented through the analysis of selected passages from their works, such as Raghunāthābhyudaya (The rise of Raghunātha), Śrīrāmāyaṇasāratilaka (The ornament of the essence of Śrīrāmāyaṇa), and other coeval sources, such as Raghunāthanāyakābhyudayamu (The rise of Raghunātha Nāyaka) by Vijayarāghava Nāyaka and Rājāgopālavilāsamu (The sports of Rājāgopāla) by Cengaḷva Kāḷakavi. The article also examines the possible relation between the courtesans in question and the Indian performative art known as avadhāna .
Don’t Let’s Look at the Nanny: Tracing the Photographic Occlusion of the Black Nanny in Alexandra Fuller’s Don’t Let’s Go to the Dogs Tonight: An African Childhood
Authors: Pyner Beth
Published: November 2023

ABSTRACT: Providing the first sustained scholarly analysis of the Black nanny figure in Alexandra Fuller’s Don’t Let’s Go to the Dogs Tonight: An African Childhood (2001), this article highlights the memoir’s problematic visual economies as a white-written memoir of a colonial Southern African childhood with occluded photographic representations of Black women nannies. The article signals the limitations of hegemonic approaches to images, particularly in materials treated primarily as literary. Only by accounting for Fuller’s use of photography can we appreciate the importance and shape of the memoir’s racial and gender politics. Drawing on theories of family photography and intersectional, Black feminist accounts of visibility, the article analyzes the two images of Black women in Don’t Let’s Go to the Dogs Tonight , revealing a dialectic of whiteness producing Blackness as its abject other, while Blackness remains crucial to, but occluded from, the production of the white colonial family. The article concludes that the co-constitution of visible whiteness and occluded Blackness mirrors the ethnocentric and masculinist hierarchies of colonialism and maps onto hegemonic medial hierarchies that privilege text above image. Where Blackness/images are the denigrated other—necessary but occluded—whiteness/text is a figuration of authority. This dynamic underscores the need for more perceptive and decolonizing methods of reading texts containing images.
Black Women and Self-Care: A Black Feminist Reading of Upile Chisala’s Poetry
Authors: Lipenga Ken Junior , Mtenje Asante Lucy
Published: November 2023

ABSTRACT: This article examines poems of the young Black writer Upile Chisala selected from her three poetry collections, soft magic (2019), nectar (2019), and a fire like you (2020). The poet advances an ethic of self-care—driven by the simultaneous needs for deliberate selfishness and sisterhood—directed at Black women in Africa and the diaspora as the first step towards their mental, physical, and social well-being. Adopting the notion of self-care as advanced by a number of Black feminist scholars, the article examines the way Chisala tackles the topic through a three-pronged trajectory, emphasizing deliberate love of the self, the rejection of toxic relationships, and Black women’s (re)discovery of their voice.
Evolution and Political Revolution in Blackwood's Periodical Poetry
Authors: Dewitt Anne
Published: November 2023

Abstract: In May 1861, the middlebrow British monthly Blackwood's Edinburgh Magazine published a comic poem titled "The Origin of Species." While foregrounding Charles Darwin, the poem portrays evolution as teleological, progressive, and driven by the agency and desires of individual organisms—a misrepresentation of Darwin's theory. I argue that the poem undertakes this misrepresentation deliberately: the version of evolution it attributes to Darwin was associated with radical politics and threats to the social order. The Blackwood's poems call up these political associations to reduce the novelty of Darwin's theory and to hint at its dangerous social tendencies.
The refracted portrait of the artist: The cultural reproduction of artist attributes through the Venice Film Festival
Authors: Blair Bonnie , Bok Jared
Published: November 2023

Research has shown how ‘cultural consecration’ grants economic and symbolic benefits to cultural producers and their creations. Yet few studies adopting this approach have explored the content of these creations themselves. Consecration is a contagious process, and culturally consecrated objects also consecrate the representations contained within. Drawing on insights from the sociology of culture and art history, this study qualitatively analyses and illustrates the reproduction of three social roles of ‘the artist’ in biopics nominated for the Venice Film Festival’s Golden Lion Award since the year 2000. Focusing on representations of prominent artists who themselves are consecrated in both popular and artistic circles, this article shows how social characteristics of artists – individual exceptionalism, social separation and artistic autonomy – are reproduced through the medium of consecrated film. It concludes by considering the practical implications of such reproductions and avenues for future research on the consecration of cultural content.
Orientação e Grounding diante das incertezas, dúvidas e do Não-Saber - Orientation and Grounding in the face od uncertainties, doubts and the Not-Knowing
Authors: Rousseau Daniel
Published: November 2023

Resumo: Nossa vida é permeada por incertezas, e isto veio mais à tona com a Pandemia Covid-19. Através da dualidade opositora e excludente, na Onisciência e Onipotência, creditamos ao conhecimento, ao controle e ao poder, garantia absoluta de nos livrar de nossas incertezas, bem como das inseguranças e angústias decorrentes; no outro extremo, desprezamos o conhecimento e qualquer possibilidade de cuidado, ordem, segurança, previsibilidade e limites diante da vida, o que nos leva à precariedade existencial. Para além destes extremos, pela via da complexidade e singularidade, podemos encontrar princípios e possibilidades para orientação e grounding diante das incertezas, das dúvidas e do não-saber, compreendendo os riscos e a impossibilidade de garantias absolutas (a única garantia absoluta que temos na vida é a da morte), sem cairmos na arrogância do poder e do conhecimento, nem no culto à estupidez, à falta de limites, ao ceticismo generalizado e à liberdade irresponsável.Palavras-Chave: Grounding, Incerteza, Não-saber, Pensamento complexo.  Abstract: Our life is permeated by uncertainties, and this came to the fore with the Covid-19 Pandemic.  Through the opposing and excluding duality, in Omniscience and Omnipotence, we credit knowledge, control and power, with the absolute guarantee of getting rid of our uncertainties, as well as the resulting insecurities and anxieties;  at the other extreme, we despise knowledge and any possibility of care, order, security, predictability and limits in the face of life, which leads us to existential precariousness.  Beyond these extremes, through complexity and uniqueness, we can find principles and possibilities for guidance and grounding in the face of uncertainties, doubts and not knowing, understanding the risks and the impossibility of absolute guarantees (the only absolute guarantee we have in life is death), without falling into the arrogance of power and knowledge, nor into the cult of stupidity, lack of limits, generalized skepticism and irresponsible freedom.Keywords: Grounding, Uncertainty, Not-knowing, Complex thinking.