bluuebunny/crossref_metadata_2025 huggingface dataset:
A beleértett külső hatáskörök esete
Authors: Budai Péter
Published: November 2023

Az uniós külkapcsolati jog témája kevéssé van a középpontban a magyar uniós jogi diskurzusban, így a beleértett külső hatáskörök is már-már misztikusnak tűnhetnek. A téma ugyanakkor a legkevésbé sem titokzatos, annak fejlődése inkább a pragmatizmus jelenlétére bizonyíték az uniós jog fejlődésében, mivel a beleértett külső hatásköröket már az EGK idejében is a hatáskörök bővítésére használták. A cikk célja, hogy bemutassa, hogyan jelenik meg ez a pragmatizmus időről időre a beleértett külső hatáskörök fejlődése esetén. Ehhez a cikk támaszkodik Sinclair elméletére is, aki a nemzetközi szervezetek jogában a hatáskör-növekedés jelenségét egyes esetekben összefüggő folyamatban látja. A cikk ennek megfelelően ismerteti a C-22/70. sz. Európai Bizottság kontra Tanács (ERTA-) ügyet, ideértve az ügy során elhangzott főbb érveket, valamint az ügyhöz kapcsolódó releváns körülményeket. Ezt követi a beleértett külső hatáskörök expanziójának ismertetése, amely rá kíván mutatni a beleértett külső hatáskörök eseteinek kibontakozására. A tanulmány végül rámutat arra, hogy az Alkotmányszerződés és a lisszaboni reformok alatt milyen „párbeszéd” alakult ki a tagállamok és a Bíróság között.
ФОРМИ І МЕТОДИ ОЦІНЮВАННЯ ЕКОЛОГІЧНИХ ЗБИТКІВ ВІД ВІЙНИ
Authors: Верстяк А.В.
Published: November 2023

Здійснений аналіз виявив, що збитки завдані економіці України внаслідок повномасштабного вторгнення РФ є суттєвими, а орієнтовний прогноз відновлення її відновлення оцінюється 2030 роком. Не дивлячись й на очевидні екологічні збитки від війни, їх реальна оцінка є складним завданням, адже про забруднення, викликане військовою діяльністю, не повідомляється, оскільки робота систем моніторингу була порушена або вони були знищені, і така шкода продовжує накопичуватися. Запропоновано авторське бачення терміну «еколого-економічний збиток від війни». Здійснено аналіз відкритих інформаційних джерел та ресурсів оцінки збитків завданих Україні внаслідок збройної агресії росії та виявлено, що їх результати суттєво різняться. Наведено методики та механізми оцінки грошових втрат екологічних збитків від військових дій.
ASSESSMENT OF MARKET EQUILIBRIUM OF BASIC DYNAMIC MODELS
Authors: Білоусова Т.П.
Published: November 2023

The main models used to assess the market equilibrium are analyzed. Refinements of the mechanism of interaction between supply and demand are proposed, which are necessary for practical forecasting in the stock market. Elements of differential calculus are used for forecasting. The solution of the differential equation shows that the movement of the market cannot be described by a single equation. If demand changes, then this will entail a change in supply, which balances the market. The full cycle of market fluctuations, by analogy with the cobweb pattern, is divided into 4 quarters of the π/2 period. An assessment is made of the stability of the market equilibrium for each period. To do this, on each π/2 period, we write down and solve the differential equation. On the basis of research, the dependence of the change in the amplitude of market fluctuations during one half-period and the equation of market fluctuations relative to the equilibrium point was obtained.
Experimental Study of Local Scour Around Circularcrossing and Square-crossing Piles in Waves and Current
Authors: Shengtao Du , Chaolin Wang , Zhiyong Zhang , Guoxiang Wu , Bingchen Liang
Published: November 2023

Experimental tests of local scour around a circular-crossing pile (CCP) and a square-crossing pile (SCP) were carried out to study the effects of superimposed waves upon current in the local scour process and the differences in characteristics in the two shaped piles. Non-uniform sediment with a gradation of 1.6 was used in the tests. Stokes waves of 0.11 m in height and 1.6 s in period were generated in a 50 cm water depth flume. The ratios of Shields number to critical Shields number in the current-only tests, the waves-only test, and the waves-current tests were individually 0.90, 1.48, and 1.83, respectively. The Keulegan-Carpenter number (KC) was kept at a constant value of 2.9, which was expected not to generate a horseshoe vortex or a wake vortex in the waves-only condition. The topography at various scour durations, temporal bed elevation profiles, and temporal scour depths were measured and discussed. The results showed that sediment backfilling into the scour hole was caused by moving sand ripples. The limit value under which the horseshoe vortex or wake vortex was absent in the waves-only condition was reduced in the waves-current condition. The temporal bed elevation profiles and scour depth development were very similar between the SCP and CCP, although the scour hole and sand dunes in the former were individually deeper and larger than the latter. The maximum scour depth in the SCP was nearly equal to that of the CCP in the waves-current condition, but it was much larger in the current-only condition.
REHABILITATION OF DRUGS ABUSE VICTIMS THROUGH ISLAMIC PSYCHOTHERAPY APPROACH AT IPWL D’WIN FOUNDATION BANGKA BELITUNG
Authors: Armika Armika , Dewi Indah Kusuma , Zayadi Zayadi
Published: November 2023

Islamic psychotherapy is an attempt to help heal and treat clients through the emotional and spiritual aspects of a person in an Islamic way and does not contradict or conflict with Islamic religious teachings which are based on the guidance of the Qur’an and the Hadith. The purpose of this study is to find out how successful Islamic psychotherapy is for clients in drug abuse rehabilitation at IPWL D’WIN Foundation Bangka Belitung. Based on the results of the study, it can be concluded that the success of Islamic psychotherapy for clients in IPWL D’WIN Foundation rehabilitation is carried out through providing deepening, appreciation, and religious practice that can grow and increase the spiritual strength of drug addict clients so that they can recover and be healthy again and can minimize re-engagement in drug abuse.
СПРИЙНЯТТЯ ВЛАСНОЇ СЕКСУАЛЬНОСТІ ЖІНКАМИ РІЗНИХ ВІКОВИХ ГРУП
Authors: Свиридова Лілія Мамедівна , Крайніков Едуард Владиславович
Published: November 2023

Мета статті – теоретично обґрунтувати сутність жіночої сексуальності на сучасному етапі та емпірично визначити психологічні особливості сприйняття жінками власної сексуальності. Методи: теоретичні (аналіз, систематизація, класифікація, узагальнення наукової інформації за темою дослідження); емпіричні: Опитувальник сексуальних установок Г. Айзенка, методика «Індекс жіночої сексуальної функції», методика «Оцінка власної зовнішності», ASI-R; статистичні: описові статистики, коефіцієнт лінійної кореляції Пірсона. Результати. Установлено, що у досліджених жінок виражений високий рівень сексуальної невротичності, низький рівень сексуальної сором’язливості та низький рівень сексуальної збудливості. Серед характеристик жіночої сексуальності найбільш вираженим є «потяг», дещо менш виражені «збудження», «любрикація», «оргазм», «задоволення», «біль». У жінок досить висока самооцінка власної зовнішності. Порівняння особливостей сексуальності жінок за віковими групами не виявив статистичних відмінностей, що свідчить про індивідуальний характер жіночої сексуальності, який не залежить від віку. Кореляційний аналіз виявив, що у досліджуваних жінок сексуальна функція має зв’язок із високою збудливістю та низькою сором’язливістю. Висока сексуальна функція пов’язана з низькою мотивацією до власного тіла. Висновки. Отримані результати є корисними для психологів, сексологів та інших фахівців і дають можливість глибше зрозуміти природу сексуальності сучасної жінки, її проблемні місця та будувати відповідно консультативну та практичну сексологічну допомогу. Доведений зв’язок між рівнем сексуальності, сексуальних установок та оцінкою власного тіла робить вагомий внесок у побудову програм розроблення індивідуальних та групових підходів до роботи з жінками щодо формування позитивного сприймання власної сексуальності. Також результати дослідження можуть бути використані як додатковий матеріал під час викладання дисциплін «Психологія статі», «Основи сексології» для студентів закладів вищої освіти.
НАСИЛЛЯ ДИТИНИ: ПСИХОАНАЛІЗ, ПСИХОТЕРАПІЯ МЕНТАЛІЗАЦІЇ ТА ДОСВІД АЛЬТЕРНАТИВНИХ ПОСЛУГ У БРАЗИЛІЇ
Authors: Вірна Жанна Петрівна
Published: November 2023

Презентований матеріал розкриває історично-методологічний аспект психоаналізу насилля дитини на матеріалі південноамериканських теоретичних та прикладних досліджень. Мета статті полягає у бібліографічному огляді основних психоаналітичних основ розуміння насилля (на прикладі сексуального) та обговоренні сучасних проблем його прояву у дискурсі соціальної уразливості дітей та психотерапевтичних технологій роботи з ними. Визначений теоретико-методологічний курс аналізу сексуального насилля дитини використовує методи, що складаються з дослідницьких процедур бібліографічного огляду психоаналітичних досліджень і терапевтичних рекомендацій. Основними результатами дослідження є узагальнення положень, що психоаналіз З. Фройда становив основу розуміння феномену насилля і агресивності, на якій вибудовуються допоміжні засоби глибинного вияву інтрапсихічних аспектів переживання наслідків травмування сексуальним насильством дитини; розглянуто базові характеристики сексуального насилля дитини (ознаки, види, наслідки) та наголошено на необхідності визначення змісту психологічних травм (симптомів) дитини та застосування психотерапевтичних технологій психоаналітичного спрямування, серед яких психотерапія менталізації займає провідну позицію; розширено розуміння процесів насильницьких ситуацій через роль інтерналізованих об’єктних відносин та стиль прив’язаності дитини; підкреслено, що травматичний сексуальний досвід пов’язаний із ментальною негативною проєктивною ідентифікацією; розкрито психологічні аспекти порушення менталізації, які визначають логіку психотерапії менталізації; зазначено прикладні дослідження з порушення менталізації та досвід бразильських психоаналітиків у психосоціальній допомозі дітям і підліткам, які стали жертвами сексуального насилля; окреслено мету, варіації та етапи проведення психотерапії менталізації; презентовані альтернативи забезпечення доступу до психотерапевтичного лікування дітей та підлітків, які стали жертвами сексуального насилля, системою соціально-психологічної допомоги. У висновках зазначено, що презентовані альтернативні варіанти психосоціальної допомоги з реструктуризації травми насилля, підвищення самооцінки та навчання захисній поведінці в дитячому віці знижує ризик повторної віктимації та розвитку агресивної поведінки.
PENGARUH MODEL PEMBELAJARAN KOOPERATIF TIPE JIGSAW TERHADAP KEMAMPUAN MEMBACA DONGENG DI KELAS VII MTs TERPADU RIYADUL BADIAH
Authors: Regina Mayang , Fajar Sukma Nur Alam
Published: November 2023

Penelitian ini memiliki latar belakang kurangnya kemampuan siswa dalam membaca dongeng di MTs Terpadu Riyadul Badiah. Oleh karena itu penelitian ini memiliki tujuan antara lain untuk: satu, kemampuan membaca dongeng siswa sebelum menggunakan model pembelajaran kooperatif tipe jigsaw. dua, mengetahui kemampuan membaca dongeng siswa setelah menggunakan model pembelajaran kooperatif tipe jigsaw. tiga, mengetahui pengaruh model pembelajaran kooperatif tipe jigsaw terhadap kemampuan membaca dongeng siswa di MTs kelas VII. Metode penelitian yang dipakai adalah metode eksperimen dan jenis penelitiannya adalah kuantitatif. Sampel dari penelitian ini adalah siswa kelas VII A selaku kelas eksperimen dan siswa kelas VII B selaku kelas kontrol. Teknik mengumpulkan data melalui observasi, wawancara dan the prites postes control group design. Hasil penelitian menghasilkan model kooperatif tipe jigsaw berpengaruh terhadap hasil membaca dongeng siswa, jika sebelum menggunakan model pembelajaran kooperatif tipe jigsaw kelas eksperimen mempunyai nilai rata-rata (mean) jauh dari nilai KKM (Kriteria Ketuntasan Minimal)begitu pun dengan kelas kontrol jauh dari nilai KKM (Kriteria Ketuntasan Minimal). Setelah menggunakan model pembelajaran kooperatif tipe jigsaw nilai rata-rata (mean) kelas eksperiman yang sama dengan nilai KKM (Kriteria Ketuntasan Minimal) meningkat. Dan dilihat dari uji-t nilai sig.lebih kecil. Maka dari itu model pembelajaran kooperatif tipe jigsaw berpengaruh terhadap kemampuan membaca dongeng siswa di kelas VII MTs Terpadu Riyadul Badiah.
Pengaruh Latihan Metode Drill Terhadap Kemampuan Akurasi Passing Bola Permainan Futsal Pada Siswa Ekstrakulikuler SMPN 1 BEBER
Authors: Yarobi Mochamad
Published: November 2023

Mochamad Yarobi (NIM 182223074), Pengaruh Latihan Metode Drill TerhadapKemampuan Akurasi Passing Bola Permainan Futsal Pada Siswa EkstrakulikulerSMPN 1 BEBER. Program Studi Pendidikan Jasmani, Kesehatan dan Rekreasi.Tujuan penelitian ini adalah untuk mengetahui pengaruh latihan Metode drillterhadap kemampuan akurasi passing bola permaianan futsal pada siswaekstrakulikuler SMPN 1 BEBER. Penelitian ini menggunakan metode penelitianeksperimen. Populasi dan sampel dalam penelitian ini adalah siswaekstrakulikuler SMPN 1 BEBER dengan sampel 12 0rang. Instrumen penelitianyang digunakan dalam penelitian ini adalah tes passing dengan jarak 15 meter darigawang. Hasil analisis dan pengolahan data preetest diperoleh passing terendah 4,passing tertinggi 7, sedangkan hasil data posttest diperoleh passing terendah 5,passing tertinggi 9 dalam 10 kali percobaan menggunakan kaki kanan 5 kali dankaki kiri 5 kali. Hal ini menunjukan adanya peningkatan terhadap kemampuanpassing siswa ekstrakulikuler SMPN 1 BEBER. Berdasarkan pengujianmenunjukan bahwa kedua tes distribusinya normal. Oleh karena itu untuk mengujihipotesis menggunakan uji independent samples t-test nilai pre-test dan post-testmenunjukan nilai nilai Sig p 0,730 >0,05 pada bagian Equality of Means sebesar0.000, karena nilai Sig < 0.005, maka dapat disimpulkan bahwa ada pengaruhyang signifikan untuk Kemampuan Akurasi passing Menggunakan Metode DrillTerhadap siswa ektrakulikulikuler SMPN 1 BEBER.Kata Kunci : Akurasi passing dan metode drill
PENGARUH SMALL SIDED GAME DALAM MENINGKATKAN KAPASITAS AEROBIK PEMAIN BOLA VOLI PUTRI STKIP MUHAMMADIYAH KUNINGAN
Authors: Pitri Pitri Nurpaijah
Published: November 2023

Pitri Nurpaijah (NIM : 182223089), dengan judul “PENGARUH SMALL SIDED GAME DALAM MENINGKATKAN KAPASITAS AEROBIK PEMAIN BOLA VOLI PUTRI STKIP MUHAMMADIYAH KUNINGAN” Penelitian ini bertujuan untuk meningkatkan VO2Max pada pemain Bola voli putri STKIP Muhammadiyah Kuningan melalui metode Latihan Small sided games. Penelitian ini merupakan penelitian eksperimen dan Teknik pengumpulan data menggunakan One Group Pretest-Posttest dengan jumlah populasi 12 orang pemain bola voli STKIP Muhammafiyah Kuningan, menggunakan instrument test 2,4km . Metode penelitian dengan menggunakan metode penelitian kuantitatif, teknik analisis data ini menggunakan Uji Normalitas dan Uji Homogenitas, uji normalitas data ini mengunakan uji Kolmogorov Smirnov dengan nilai signifikan untuk data pretest 0,042 dan untuk data posttest 0,017 lebih besar dari 0,05 maka data berdistribusi normal. Nilai signifikan untuk Levene statistic 0,010 > 0,05, maka berdistribusi normal. Selanjutnya nilai t hitung yang di dapat 9,039. Subjek penelitian Mahasiswa yang mengikuti UKM Bola Voli Putri STKIP Muhammadiyah Kuningan.
SH2 domain-containing inositol 5-phosphatases support the survival of Burkitt lymphoma cells by promoting energy metabolism
Authors: Mayr Florian , Kruse Vanessa , Fuhrmann Dominik C. , Wolf Sebastian , Löber Jens , Alsouri Saed , Paglilla Nadia , Lee Kwang , Chapuy Björn , Brüne Bernhard , Zenz Thorsten , Häupl Björn , Oellerich Thomas , Engelke Michael
Published: November 2023

Burkitt lymphoma cells (BL) exploit antigen-independent tonic signals transduced by the B cell antigen receptor (BCR) for their survival, but the molecular details of the rewired BLspecific BCR signal network remain unclear. A loss of function screen revealed the SH2 domain-containing 5`-inositol phosphatase 2 (SHIP2) as a potential modulator of BL fitness. We characterized the role of SHIP2 in BL survival in several BL cell models and show that perturbing SHIP2 function renders cells more susceptible to apoptosis, while attenuating proliferation in a BCR-dependent manner. Unexpectedly, SHIP2 deficiency did neither affect PI3K survival signals nor MAPK activity, but attenuated ATP production. We found that an efficient energy metabolism in BL cells requires phosphatidylinositol-3,4-bisphosphate (PI(3,4)P2), which is the enzymatic product of SHIP proteins. Consistently, interference with the function of SHIP1 and SHIP2 augments BL cell susceptibility to PI3K inhibition. Notably, we here provide a molecular basis of how tonic BCR signals are connected to energy supply, which is particularly important for such an aggressively growing neoplasia. These findings may help to improve therapies for the treatment of BL by limiting energy metabolism through the inhibition of SHIP proteins, which renders BL cells more susceptible to the targeting of survival signals.
STRATEGI MEMBANGUN KOMUNIKASI DUA ARAH ANTARA GURU DAN MURID PADA PEMBELAJARAN DARING DI MTs. AL-ROSYID DANDER BOJONEGORO
Authors: Choiri Moh. Miftahul , Auliyaur Rokhim  , Cindarbumi Festian
Published: November 2023

Abstrak: Artikel ini berupaya mengkaji tentang pentingnya sebuah komunikasi dalam pembelajaran. Komunikasi merupakan syarat utama keberhasilan sebuah proses pembelajaran. Komunikasi adalah satu cara atau teknik yang diterapkan oleh guru dalam kegiatan belajar mengajar di kelas atau pelaksanaan pembelajaran daring. Pembelajaran yang bermakna salah satunya bisa dilakukan ketika pendidik dapat membangun komunikasi yang hangat dalam pembelajaran. Sebab pembelajaran merupakan hal penting dalam pendidikan. Pembelajaran mengharuskan adanya keaktifan antara pendidik dan peserta didik. Untuk itu penelitian ini bertujuan untuk mengkaji arti pentingnya sebuah pembelajaran yang kreatif, pembelajaran humanis yang menekankan adanya keseimbangan dalam berkomunikasi antara pendidik dan peserta didik. Selain itu  bagaimana strategi atau trik yang diterapkan oleh guru dalam membangun komunikasi yang aktif khususnya dalam pembelajaran daring. Pada akhirnya pembelajaran menjadi efektif dan bermakna.

Metode penelitian yang digunakan adalah menggunakan metode dokumentasi, observasi dan wawancara yang dilaksanakan di MTs. Al-Rosyid Dander Bojonegoro. Dengan harapan penelitian ini bermanfaat bagi semua masyarakat, pihak sekolah dan khususnya bagi peneliti sendiri.

 

         Kata kunci: Komunikasi dua arah, Pembelajaran daring.
The many faces of SIRT6 in the retina and retinal pigment epithelium
Authors: Cheng Jie , Keuthan Casey J. , Esumi Noriko
Published: November 2023

Sirtuin 6 (SIRT6) is a member of the mammalian sirtuin family of NAD+-dependent protein deacylases, homologues of the yeast silent information regulator 2 (Sir2). SIRT6 has remarkably diverse functions and plays a key role in a variety of biological processes for maintaining cellular and organismal homeostasis. In this review, our primary aim is to summarize recent progress in understanding SIRT6’s functions in the retina and retinal pigment epithelium (RPE), with the hope of further drawing interests in SIRT6 to increase efforts in exploring the therapeutic potential of this unique protein in the vision field. Before describing SIRT6’s role in the eye, we first discuss SIRT6’s general functions in a wide range of biological contexts. SIRT6 plays an important role in gene silencing, metabolism, DNA repair, antioxidant defense, inflammation, aging and longevity, early development, and stress response. In addition, recent studies have revealed SIRT6’s role in macrophage polarization and mitochondrial homeostasis. Despite being initially understudied in the context of the eye, recent efforts have begun to elucidate the critical functions of SIRT6 in the retina and RPE. In the retina, SIRT6 is essential for adult retinal function, regulates energy metabolism by suppressing glycolysis that affects photoreceptor cell survival, protects retinal ganglion cells from oxidative stress, and plays a role in Müller cells during early neurodegenerative events in diabetic retinopathy. In the RPE, SIRT6 activates autophagy in culture and protects against oxidative stress in mice. Taken together, this review demonstrates that better understanding of SIRT6’s functions and their mechanisms, both in and out of the context of the eye, holds great promise for the development of SIRT6-targeted strategies for prevention and treatment of blinding eye diseases.
Mathematical modeling and application of IL-1β/TNF signaling pathway in regulating chondrocyte apoptosis
Authors: Wang Yishu , Liu Jingxiang , Huang Boyan , Long Xiaojun , Su Xiuyun , Sun Deshun
Published: November 2023

Introduction: Mathematical model can be used to model complex biological processes, and have shown potential in describing apoptosis in chondrocytes.

Method: In order to investigate the regulatory mechanisms of TNF signaling pathway in regulating chondrocyte apoptosis, a fractional-order differential equation model is proposed to describe the dynamic behavior and mutual interaction of apoptosis-related genes under the activation of TNF signaling pathway. Compared with the traditional molecular biology techniques, the proposed mathematical modeling has advantages to providing a more comprehensive understanding of the regulatory mechanisms of TNF signaling pathway in chondrocyte apoptosis.

Result: In this paper, differentially expressed genes induced by IL-1β in human chondrocyte apoptosis are screened using high-throughput sequencing. It is found that they were significantly enriched in the TNF signaling pathway. Therefore, a mathematical model of the TNF signaling pathway is built. Using real-time PCR experiments, mRNA data is measured and used to identify the model parameters, as well as the correlation coefficient. Finally, the sensitivity of the model parameters is discussed by using numerical simulation methods, which can be used to predict the effects of different interventions and explore the optimal intervention strategies for regulating chondrocyte apoptosis.

Discussion: Therefore, fractional-order differential equation modeling plays an important role in understanding the regulatory mechanisms of TNF signaling pathway in chondrocyte apoptosis and its potential clinical applications.
A low carbon balance triggers Microvine inflorescence abscission at high temperatures
Authors: Luchaire Nathalie , Torregrosa Laurent Jean-Marie , Gibon Yves , Rienth Markus , Romieu Charles , Ageorges Agnès , Turc Olivier , Muller Bertrand , Pellegrino Anne
Published: November 2023

Introduction

Global warming is a major threat to yield sustainability in most crops, including grapevine. Whether or not grapevine fruitfulness is impaired by an imbalance between carbon supply and demand caused by high temperatures was investigated in the present study.

Methods

Five experiments were conducted on Microvine, a natural mutant of grapevine that is insensitive to gibberellins, presents with a dwarf stature, and has continuous flowering along the vegetative axes. The last property was used to infer temporal patterns of inflorescence development from their spatial distribution at harvest. Two sets of plants, characterized by low or high levels of initial shoot vigor, were grown under contrasting day and night temperatures: 22°C/12°C and 30°C/20°C.

Results and discussion

The rate of leaf development of the main shoot was stable, regardless of the initial vigor and temperature treatment. In contrast, the warm temperatures delayed the timing of flowering for low-vigor plants or the onset of ripening for high-vigor plants. Fruitfulness was impaired by high temperatures as a result of the abscission of young inflorescences (before the flowering stage). From a careful spatiotemporal analysis of cluster abscission, we concluded that inflorescence drop under elevated temperatures was triggered by the increase in plant carbon demand due to the oldest clusters starting to unload sugars. Elevated temperatures may have also lowered the carbohydrate supply in the zone of inflorescence abscission due to the higher leaf respiration while all organ growth demand was maintained. Interestingly, inflorescence abscission occurred earlier when whole-plant vigor was low and was followed by a recovery period, in spite of a lower non-structural sugar status than in high-vigor plants. Taken together, our results suggest that inflorescence abscission is linked to the variations of the carbon pool induced by changes in temperature and not to its absolute value. Our study, therefore, provides new hypotheses about the impacts of warm temperatures on the regulation of temperature-induced reproductive failure in grapevine.
ERP evidence of attentional somatosensory processing and stimulus-response coupling under different hand and arm postures
Authors: Kida Tetsuo , Kaneda Takeshi , Nishihira Yoshiaki
Published: November 2023

We investigated (1) the effects of divided and focused attention on event-related brain potentials (ERPs) elicited by somatosensory stimulation under different response modes, (2) the effects of hand position (closely-placed vs. separated hands) and arm posture (crossed vs. uncrossed forearms) on the attentional modulation of somatosensory ERPs, and (3) changes in the coupling of stimulus- and response-related processes by somatosensory attention using a single-trial analysis of P300 latency and reaction times. Electrocutaneous stimulation was presented randomly to the thumb or middle finger of the left or right hand at random interstimulus intervals (700–900 ms). Subjects attended unilaterally or bilaterally to stimuli in order to detect target stimuli by a motor response or counting. The effects of unilaterally-focused attention were also tested under different hand and arm positions. The amplitude of N140 in the divided attention condition was intermediate between unilaterally attended and unattended stimuli in the unilaterally-focused attention condition in both the mental counting and motor response tasks. Attended infrequent (target) stimuli elicited greater P300 in the unilaterally attention condition than in the divided attention condition. P300 latency was longer in the divided attention condition than in the unilaterally-focused attention condition in the motor response task, but remained unchanged in the counting task. Closely locating the hands had no impact, whereas crossing the forearms decreased the attentional enhancement in N140 amplitude. In contrast, these two manipulations uniformly decreased P300 amplitude and increased P300 latency. The correlation between single-trial P300 latency and RT was decreased by crossed forearms, but not by divided attention or closely-placed hands. Therefore, the present results indicate that focused and divided attention differently affected middle latency and late processing, and that hand position and arm posture also differently affected attentional processes and stimulus–response coupling.
Estradiol mediates sex differences in aversion-resistant alcohol intake
Authors: Arnold Miranda E. , Decker Ramirez Ellie B. , Beugelsdyk Lauren A. , Siano Kuzolitz M. Vitória , Jiang Qiuyun , Schank Jesse R.
Published: November 2023

Introduction

Alcohol consumption despite negative consequences is a core symptom of alcohol use disorder. This can be modeled in mice by pairing aversive stimuli with alcohol consumption, such as adding the bitter tastant quinine to the alcohol solution. If an animal continues to drink alcohol despite such negative stimuli, this is typically considered aversion-resistant, or inflexible, drinking behavior. Previous studies in our lab have found that females are more aversion-resistant than males in that they tolerate higher concentrations of quinine before they suppress their alcohol intake. Interestingly, we did not observe any differences in intake across the estrous cycle. In regards to neuronal activation patterns during quinine-alcohol intake, we have found that male mice show higher levels of activation in the ventromedial prefrontal cortex and posterior insular cortex, while females show higher levels of activation in the ventral tegmental area.

Methods

In the experiments presented here, we conducted ovariectomies to further examine the role of circulating sex hormones in aversion-resistant alcohol intake and neuronal activation patterns. Furthermore, we used hormonal addback of estradiol or progesterone to determine which ovarian sex hormone mediates aversion-resistant consumption.

Results

We found that ovariectomy reduced quinine-adulterated alcohol intake, demonstrating that circulating sex hormones play a role in this behavior. We also observed reduced neuronal activation in the VTA of ovariectomized mice compared to sham females, and that estradiol supplementation reversed the effect of ovariectomy on quinine-alcohol intake.

Discussion

Taken together with our prior data, these findings suggest that circulating estradiol contributes to the expression of aversion-resistant alcohol intake and neuronal activity in the VTA. However, since this behavior is not affected by the estrous cycle, we believe this is due to a threshold level of this hormone, as opposed to fluctuations that occur across the estrous cycle.
Evidence of whole-body vibration exercises on body composition changes in older individuals: a systematic review and meta-analysis
Authors: Reis-Silva Aline , Coelho-Oliveira Ana Carolina , Moura-Fernandes Márcia Cristina , Bruno Bessa Monteiro-Oliveira , Batouli-Santos Daniel , Bernardo-Filho Mario , de Sá Caputo Danúbia da Cunha
Published: November 2023

Introduction: The aging process is associated with changes in body composition, including fat gain and skeletal muscle loss from middle age onward. Moreover, increased risk of functional decline and the development of chronic diseases are also related to aging.

Objective: This systematic review and meta-analysis aimed to evaluate the effects of whole-body vibration exercise (WBVE), as a physical exercise, on body composition in people over 60 years of age.

Methods: Searches were performed on PubMed, Scopus, Web of Science, and Embase. Only randomized clinical trials evaluating the effects of WBVE on body composition in older individuals were considered. The methodological quality of the studies involved was assessed using the Physiotherapy Evidence Database (PEDro) scale, recommendations from the Cochrane Collaboration were used to assess risk of bias, and quality of evidence was assessed using the Grading of Recommendation, Assessment, Development, and Evaluation (GRADE) methodology. RevMan 5.4 was used to calculate standardized mean differences and confidence intervals of 95% (CIs).

Results: Eight studies were included in this review with a mean methodological quality score of 7.5, which is considered high quality on the PEDro scale. The included studies suggest that more robust research with protocols and well-designed comparison groups is required to better assess changes in the body composition of older individuals through WBVE. Quantitative results were calculated, with differences in weighted means, differences in standardized means, and 95% confidence intervals (CIs).

Conclusion: WBVE evaluated by the studies included in this review did not demonstrate improvements in body composition, and no significant effect of WBVE was found on fat mass with standardized differences (SD = −1.92; 95% CI: –4.81 to −0.98; p = 0.19), lean mass with standardized mean differences (SMD = 0.06 CI 95% [–0.21; −0.33]; p = 0.67), or skeletal muscle mass with standardized differences (SD = 0.10; CI 95% [–1.62; 1.83]; p = 0.91). Therefore, to date, there is lack of adequate evidence to state that WBVE can benefit the body composition of men and women over 60 years of age. However, further studies are required to better understand the physiological impacts of WBVE on body composition.

Systematic Review Registration:https://www.crd.york.ac.uk/prospero/#myprosperoCRD42021248871, identifier CRD42021248871.
Systematic identification of reference genes for qRT-PCR of Ardisia kteniophylla A. DC under different experimental conditions and for anthocyanin-related genes studies
Authors: Wang Wentao , Zhang Xiaohang , Xu Xiaoxia , Xu Xingchou , Fu Lin , Chen Hongfeng
Published: November 2023

Ardisia kteniophylla A. DC, widely known as folk medicinal herb and ornamental plant, has been extensively investigated due to its unique leaf color, anti-cancer and other pharmacological activities. The quantitative real-time PCR (qRT-PCR) was an excellent tool for the analysis of gene expression with its high sensitivity and quantitative properties. Normalizing gene expression with stable reference genes was essential for qRT-PCR accuracy. In addition, no studies have yet been performed on the selection, verification and stability of internal reference genes suitable for A. kteniophylla, which has greatly hindered the biomolecular researches of this species. In this study, 29 candidate genes were successfully screened according to stable expression patterns of large-scale RNA seq data that from a variety of tissues and the roots of different growth stages in A. kteniophylla. The candidates were then further determined via qRT-PCR in various experimental samples, including MeJA, ABA, SA, NaCl, CuSO4, AgNO3, MnSO4, CoCl2, drought, low temperature, heat, waterlogging, wounding and oxidative stress. To assess the stability of the candidates, five commonly used strategies were employed: delta-CT, geNorm, BestKeeper, NormFinder, and the comprehensive tool RefFinder. In summary, UBC2 and UBA1 were found to be effective in accurately normalizing target gene expression in A. kteniophella regardless of experimental conditions, while PP2A-2 had the lowest stability. Additionally, to verify the reliability of the recommended reference genes under different colored leaf samples, we examined the expression patterns of six genes associated with anthocyanin synthesis and regulation. Our findings suggested that PAP1 and ANS3 may be involved in leaf color change in A. kteniphella. This study successfully identified the ideal reference gene for qRT-PCR analysis in A. kteniphella, providing a foundation for future research on gene function, particularly in the biosynthesis of anthocyanins.
Anti-pandemic resilience assessment for countries along the Belt and Road route
Authors: Zhao Laijun , Min Mengmeng , Huang Xiaoyan , Qian Ying , Zhou Lixin , Yang Pingle
Published: November 2023

Background

The COVID-19 pandemic is sweeping the world, and countries along the Belt and Road (B&R) route have also been hit hard. However, the impact varied greatly from country to country, some severely and others mildly. What factors have led to such a wide variation?

Method

In this paper, we considered institutional, infrastructural, economic, social, and technological resilience as components of overall anti-pandemic resilience, and constructed a set of indicators to evaluate this resilience for B&R countries in 2020. We evaluated the anti-pandemic resilience using the combined empowerment–VIKOR method, and classified the countries into different resilience levels by means of hierarchical clustering. The validity of the evaluation indicator system was verified by analyzing the consistency between the actual performance and the assessed resilience.

Results

The ranking results showed that Israel and Bahrain were representative of countries that had the highest resilience, Hungary and Estonia represented countries with moderate resilience, and Laos and Cambodia represented countries with the lowest resilience. We also found that countries with high resilience had much better institutional and economic resilience than countries with moderate resilience, whereas countries with low resilience lagged behind in both infrastructural and social resilience. Based on these findings, policy recommendations were offered to help B&R countries respond to future pandemics.
Mycoplasma synoviae lipid-associated membrane proteins identification and expression changes when exposed to chicken cells
Authors: Si Duoduo , Sun Jialin , Guo Lei , Yang Fei , Li Jidong , He Shenghu
Published: November 2023

Mycoplasma synoviae is a significant cause of respiratory disease and synovitis among chickens, and has an adverse economic impact on broiler breeding efforts. The present study was designed to develop a systematic understanding of the role that M. synoviae lipid-associated membrane proteins (LAMPs) may play in the virulence of this pathogen. Bioinformatics tools were used to identify 146 predicted membrane proteins and lipoproteins in the M. synoviae proteome. Then, Triton X-114 was used to extract LAMPs that were subsequently identified via LC–MS/MS. This approach enabled the detection of potential LAMPs, and the top 200 most abundant proteins detected using this strategy were subject to further analysis. M. synoviae cells (100 MOI) were exposed to chicken fibroblasts (DF-1) and macrophages (HD-11) in a 1:1 mixed culture. Analysis of LAMP transcripts identified 72 up-regulated LAMP genes which were analyzed in depth by bioinformatics. GO analysis revealed these genes to be enriched in the nucleotide binding, sulfur amino acid transmembrane transporter activity, tRNA binding, rRNA modification, and transition metal ion transport pathways. Moreover, KEGG enrichment analysis suggested that these genes were enriched in the biosynthesis of secondary metabolites, carbon metabolism, glycolysis/gluconeogenesis, and nitrogen metabolism pathways.
Learning Trajectory Tracking for an Autonomous Surface Vehicle in Urban Waterways
Authors: Sikora Toma , Schiphorst Jonathan Klein , Scattolini Riccardo
Published: November 2023

Roboat is an autonomous surface vessel (ASV) for urban waterways, developed as a research project by the AMS Institute and MIT. The platform can provide numerous functions to a city, such as transport, dynamic infrastructure, and an autonomous waste management system. This paper presents the development of a learning-based controller for the Roboat platform with the goal of achieving robustness and generalization properties. Specifically, when subject to uncertainty in the model or external disturbances, the proposed controller should be able to track set trajectories with less tracking error than the current nonlinear model predictive controller (NMPC) used on the ASV. To achieve this, a simulation of the system dynamics was developed as part of this work, based on the research presented in the literature and on the previous research performed on the Roboat platform. The simulation process also included the modeling of the necessary uncertainties and disturbances. In this simulation, a trajectory tracking agent was trained using the proximal policy optimization (PPO) algorithm. The trajectory tracking of the trained agent was then validated and compared to the current control strategy both in simulations and in the real world.
Three-Dimensional Prediction and Evaluation of Baiyanghe Uranium Deposit in the Xuemistan Volcanic Belt, Xinjiang
Authors: Bai Yun , Guo Chunying , Zhu Pengfei , Tian Jianji , He Zilan
Published: November 2023

Taking the Baiyanghe uranium deposit in Xinjiang as an example, the authors used the 3D geologic modeling and analysis software SKUA-GOCAD to establish a 3D geologic model of its topography, structure, stratum, granite, and ore body based on the study and knowledge of the geologic background, characteristics, and metallogenic rules of the deposit. Meanwhile, the authors summarized the 3D prediction model, conducted a quantitative extraction and analysis of favorable metallogenic information, and carried out the 3D prediction and study on the Baiyanghe uranium deposit by combining the 3D weights of the evidence method and the 3D informational method. Based on the analysis and prediction results, the deep prospecting target area was delineated. The 3D metallogenic prediction of the uranium deposit was achieved, which has provided technical support for the exploration of the Baiyanghe uranium deposit and a beneficial reference for the 3D metallogenic prediction of other minerals. Such a practice can provide a certain practical application value and a reference value for the research in this field.
Scolarisation des enfants étrangers à l'hôpital
Authors: Barbier-Bouvet Marie , Charlot Martine
Published: November 2023

Des enfants en cours de scolarité passent, pour cause de maladie ou de handicap, un temps plus ou moins long en hôpital, en préventorium, en établissements de rééducation et de post-cure. La maladie entraîne la mise en œuvre d'un traitement visant la guérison, ou à défaut, la stabilisation. Le handicap est plus constant (suites de poliomyélite, d'accidents de la circulation, etc.). Les maladies mentales demandent souvent une surveillance longue et fréquente.
Une classe de sixième pour jeunes Portugais
Authors: Delais Jeanne
Published: November 2023

Destiné à l’enseignement secondaire, de la sixième aux terminales, le lycée Lamartine occupe une place à part parmi les unités scolaires de Paris. En effet le cinquième environ de ses effectifs est composé d’enfants non francophones, fils et filles de migrants ou de réfugiés politiques, dont la langue maternelle et l’héritage culturel diffèrent de façon notable : une vingtaine de nationalités y sont représentées.

Déjà, avant l’arrivée de ces jeunes étrangers, ce lycée comptait beaucoup d’élèves de confession israélite dont les grands-parents et parents, originaires de Pologne ou d’Europe Centrale, parlant entre eux le yiddish, s’étaient installés aux environs de 1933 dans le neuvième arrondissement.

Après deux créations intéressantes — section de musicophiles et section d’étude des arts plastiques —, furent implantées en 1978 deux sixièmes réservées, l’une aux enfants de migrants portugais, l’autre aux hispanisants.
À la recherche d’un cours d’arabe
Authors: Charlot Martine
Published: November 2023

Des jeunes immigrés, après une longue période de scolarité, uniquement en langue française, souhaitent entreprendre l’apprentissage de la langue écrite de leur pays d’origine. Nous avons sollicité à ce sujet le témoignage de Y… jeune algérienne de la banlieue Ouest de Paris.
De l'interculturel aux stages « collèges-quartiers »
Authors: Lasnel Claude
Published: November 2023

L'interculturel à l'école n'est pas seulement la mise en place d’activités pédagogiques concernant les cultures d’origine des enfants de travailleurs migrants. Claude Lasnel, formateur au CEFISEM de Marseille, met ici l'accent sur le stage collège-quartier proposé par ce CEFISEM aux enseignants désireux d'avoir une approche plus globale de l'acte éducatif.
L'anthropologie dans la formation des enseignants
Authors: Abdallah-Pretceille Martine
Published: November 2023

Martine Abdallah-Pretceille, auteur de Des enfants non francophones à l'école : quel apprentissage ? quel français ? (paru en 1982 aux éditions Armand Colin, collection Bourrelier), analyse ici les rapports inter-personnels et inter-groupes à travers la dynamique interculturelle. Comment un pédagogue peut-il développer sa compréhension des problèmes éducatifs en s'aidant de l'anthropologie ? Dans quelle perspective inter-culturelle ?
L'animation en circonscription : formation des enseignants du primaire et scolarisation des enfants de migrants
Authors: Vimont Jean-Claude
Published: November 2023

La collaboration, en Seine Maritime, entre des Unités de Formation optionnelles de l'École Normale et plusieurs circonscriptions a permis de sensibiliser un plus grand nombre d'enseignants à la scolarisation des enfants de migrants.
Quelques éléments pour introduire un lieu d’accueil et de loisirs mères-enfants
Authors: Dupraz Luce
Published: November 2023

Les réponses séparées dans le cadre d’activités d’accueil destinées aux mères et aux enfants ont montré leurs limites. Aussi est-on conduit à mettre en place des lieux d’accueil mères-enfants. L’enjeu est d’importance : intégration sociale des familles et réussite scolaire des enfants. Après le constat, l’énoncé des principes de l’implantation et du fonctionnement de tels lieux.
Les haltes-garderies jumelées aux activités socio-éducatives destinées aux mères de famille
Authors: Roch Agnès
Published: November 2023

Un projet d’atelier mères-enfants et sa réalisation par l'ASSFAM de Vienne dans un appartement HLM situé au rez-de-chaussée d’une école fréquentée à 90% par des enfants d’origine turque.

À partir de l’observation d’une réalité locale, cette action s’inscrit dans une politique globale du quartier en associant les différents partenaires concernés.
"Il est urgent de créer des lieux d’accueil pour les enfants"
Authors: Dorkell Jacqueline , Pajot Thérèse , Weill-Ponsin Françoise , Lacaze Rose-Marie
Published: November 2023

Le quotidien de trois centres PMI de l’Essonne, en banlieue parisienne : nombreuses familles étrangères pour certaines peu ou pas adaptées à la vie en France, problèmes d’éducation, d’alimentation, problèmes dus à l’isolement des mères, aux enfants livrés à eux-mêmes pendant l’absence des parents. Richesses aussi des pratiques culturelles différentes, des échanges entre mères et entre médecins et mères.

Cri d’alarme, enfin, devant la situation de certains enfants.
Questions sur le bilinguisme des enfants issus de l’immigration
Authors: Laparra Marceline
Published: November 2023

Le bilinguisme des enfants d’immigrés recouvre des réalités très diversifiées, avec cependant deux caractéristiques communes : la minoration de la langue I, la disqualification dans la langue II.

Une hypothèse : le coût de ce bilinguisme «interdit» pourrait se trouver accru au collège par la place assignée au discours explicatif dans le processus de construction du savoir.
O transtorno de ansiedade de separação na infância: uma revisão de literatura
Authors: Fiúza Virgínia Fernandes
Published: November 2023

O presente trabalho teve como tema o transtorno de ansiedade de separação, com foco nas particularidades do mesmo na infância. Tal comorbidade é a afecção psiquiátrica mais presente em crianças e é de suma importância estuda-la. A pesquisa teve como objetivos esclarecer o diagnóstico do transtorno e evidenciar suas consequências na vida adulta. E, embora a quantidade de artigos seja escassa, foi possível perceber que o estudo aprofundado da ansiedade de separação, pode evitar adultos ansiosos no futuro. Além disso, ficou evidente a falta de pesquisas feitas no Brasil, o que talvez evidencie a falta de investimentos e a pouca importância dada para a saúde mental das crianças no país.
Studi Persepsional Risiko Kecacatan Konstruksi pada Bangunan Gedung Menggunakan Metode Failure Mode Effect and Analysis (FMEA)
Authors: Amelia
Published: November 2023

Kecacatan konstruksi perlu mendapat perhatian dalam dunia konstruksi. Cacat konstruksi atau struktur bisa berpotensi terjadinya kegagalan dan kecelakaan konstruksi. Penelitian ini bertujuan untuk mengidentifikasi dan menganalisis risiko kecacatan konstruksi berdasarkan persepsi Dinas PU Cipta Karya, Kontraktor dan Konsultan sebagai pihak yang berkepentingan pada proyek pembangunan gedung. Penelitian ini merupakan peneilitian semi kuantitatif yang dilakukan melalui penyebaran angket kuesioner yang dibagikan kepada responden yang terpilih. Selanjutnya melakukan uji statistik dan menganalisis risiko cacat konstruksi dengan menggunakan metode Failure Mode and Effect Analysis (FMEA).

Berdasarkan hasil analisis penilaian risiko kecacatan konstruksi menurut penilaian para pemangku kepentingan proyek maka didapat 6 (enam) faktor risiko kecacatan konstruksi yang prioritas yakni ; (1)Kurang atau lemahnya komunikasi dalam lingkungan proyek dengan nilai risiko sebesar 33,6; (2)Kinerja Tim Manajemen Proyek yang buruk dengan nilai risiko sebesar 30,3 ; (3)Desain yang tidak tepat dengan nilai risiko sebesar 27,88; (4)Kegiatan pengawasan di lapangan lemah dengan nilai risiko sebesar 24,60; (5)Penerapan sistem manajemen keselamatan dan kesehatan kerja (SMK3) tidak sesuai dengan regulasi dan standar dengan nilai risiko sebesar 23,04 ;(6) Kualitas material yang buruk dengan nilai risiko sebesar 19,41. Dengan adanya risiko-risiko prioritas ini maka stakeholder perlu merencanakan tindakan penanganan risiko untuk masing-masingya