bluuebunny/crossref_metadata_2025 huggingface dataset:
THE SOCIAL CREDIT SYSTEM AS A MANIFESTATION OF DEEP POLITICAL TRANSFORMATION IN CHINA
Authors: Павлова В.
Published: July 2024

Введение. Ряд аналитиков определяет китайскую систему социального кредитования «драко- новским проектом для массового наблюдения, движимым могучими технологиями для ограниче- ния личной свободы» и т. п. Статья предлагает более глубокий взгляд на проблему. Утверждается, что эта система направлена на преобразование управленческих структур в Китае и не имеет ничего общего с намерениями глобальной олигархии навязать миру «цифровую диктатуру». Методы. Использован метод анализа первичных и вторичных данных по проблеме современ- ной системы социального кредитования и её влияния на процессы общественного развития Китая. Основные идеи исследования, полученные результаты и их обсуждение. В статье проанализи- ровано стремление китайского правительства создать независимую от западных глобальных ин- формационных сетей системы социального кредита (ССК), способной преодолеть связанный с глобальными информационными сетями контроль и управление над трафиками и содержанием личной и общественной информации, развиваемых западными мировыми информационными сетя- ми, как инструмент контроля и управления мировыми общественными процессами со стороны западного капитала и западных правительств, в особенности США и их разведывательных центров. Со скептических позиций рассмотрены уже созданные западным капиталом и правительствами проекты слежения, контроля и управления информацией в глобальной сети со стороны таких за- падных проектов, как, например, глобальная электронная разведывательная система EСHELON («Пять глаз»), действующая на основе соглашения между Великобританией, США, Австралией, Новой Зеландии и Канадой. Заключение: Автор приходит к выводу о позитивности проекта ССК, развиваемого Китаем, способного стать важным фактором национальной безопасности Китая и безопасности его граждан по всему миру.
ANALYSIS OF EVAPOTRANSPIRATION DYNAMICS IN THE FOREST STANDS OF THE MIDDLE VOLGA REGION BASED ON MOD16A2 DATA DURING THE 2001-2021 PERIOD
Authors: Дергунов Д.М. , Воробьев О.Н. , Курбанов Э.А. , Лежнин С.А. , Губаев А.В. , Тарасова Л.В.
Published: July 2024

В статье представлены результаты анализа трендов эвапотранспирации лесного покрова Среднего Поволжья за 2001-2021 годы в связи c климатическими факторами и его продуктивностью (NDVI). В исследовании использовались данные временных рядов, полученных по спектрорадио- метру MODIS: продукт MOD16A2 для эвапотранспирации и MOD13Q1 для NDVI. Климатические данные температуры подстилающей поверхности (LST) и осадков (Pr) получены из набора данных TerraClimate. Исследование показало, что значения эвапотранспирации имеют тенденцию к снижению в течение всего периода исследования со скоростью 1,57 мм/год. Оценка динамики климатических показателей показала тесную связь эвапотранспирации с уровнем осадков и умеренную связь с температурой подстилающей поверхности. Главными факторами, влияющими на динамику эвапотранспирации, были количество осадков и крупные лесные пожары на территории исследования. Особенно такое снижение заметно в 2010 году, когда на территории Республики Марий Эл и Нижегородской области имели место крупные лесные пожары. Умеренные и положительные тренды наблюдаются на севере Нижегородской и Кировской областей и центральной части Республики Марий Эл, что может быть связано с зарастанием больших участков земель залежей и последующим активным участием этого объема фитомассы в потоках водного баланса лесных экосистем. Анализ данных спутниковых временных рядов показал существенное влияние деградации лесов на индекс ET.
MONITORING SOIL EROSION BY USE OF REMOTE SENSING AND GIS TECHNOLOGY IN THE SUBTROPICAL ISLAND, PINGTAN, CHINA
Authors: Tianyue Xu. , Jinming S. , Xiaomei Li.
Published: July 2024

China Soil erosion is the main environmental problem for subtropical coastal area in China with the rapid urbanization and fast development, it leads to the regional land degradation and weakening of the local ecological service. Monitoring regional soil erosion is necessary for the regional sustainable development. The paper takes Pingtan, Fujian, Chian as a case study area, it develops the technology for quantitative evaluation of soil erosion by the use of Landsat-8 imagery and DEM data based on USLE model. The results can provide benefit suggestion for local sustainable planning and eco-environmental protection.
ON-THE-FLY LAND COVER MAPPING USING MACHINE LEARNING WITH MULTISPECTRAL SATELLITE IMAGERY ON GOOGLE EARTH ENGINE
Authors: Papaiordanidis S. , Minakou C. , Gitas I.Z.
Published: July 2024

Land cover is one of the most important environmental variables used to describe natural ecosystems. Constant changes on the Earth’s surface create the need for new, up-to-date, and accurate land cover maps. During the last decades, remote sensing products have been used in conjunction with field measurements for the production of land cover maps in a cost-efficient manner. The aim of the present study was the development of a method for reliable on-the-fly land cover mapping using the Random Forest classifier and Sentinel-2 multispectral imagery on the Google Earth Engine cloud platform. The Random Forests algorithm was employed, and two classification schemes were adopted, one using the original 44 land cover classes used by the CORINE land cover product, and one using five general land cover classes (Artificial surfaces, Agricultural areas, Forest and semi-natural areas, Wetlands, and Water bodies), resulting in the generation of two land cover maps. The 2018 CORINE land cover product was used to identify training samples and validate the resulting land cover maps. The results showcased that the 44-class land cover map had an overall accuracy of 72.85% and the 5-class land cover map 88.32%. Overall, the results of this research indicate the capability of Random Forest algorithm in the reliable land cover classification.
ASSESSMENT OF LAND SURFACE TEMPERATURE AND DROUGHT INDICES FOR THE KLERKSDORP-ORKNEY-STILFONTEIN-HARTEBEESFONTEIN (KOSH) REGION
Authors: Dudumashe N. , Thomas A.
Published: July 2024

Land surface temperature (LST) is a key calculator of local climate, vegetation growth, and urban change. Spatial and temporal variation of LST over land use/land cover (LULC) features results in changes in environmental factors that influence the characteristics of the land surface. In this study, some remote sensing techniques have been applied to Landsat 8 data acquired during summer and spring seasons of years 2019, 2018, and 2013 to estimate normalized difference vegetation index (NDVI), LST, normalized difference built-up index (NDBI), three drought indices viz. vegetation supply water index (VWSI), crop water supply index (CWSI) and temperature condition index (TCI) and analysed the spatial-temporal trends in LST among major LULC of an arid part of North West Province of South Africa known as Klerksdorp-Orkney-Stilfontein-Hartebeesfontein (KOSH) region. The results shows that there is a direct negative relationship between LST and NDVI. The study compared three drought indices for monitoring the water scarcity of the area. The finding also indicates a positive relationship between LST and CWSI that is relevant to soil moisture and NDBI. The findings from the study prove the capability of optical remote sensing in monitoring LST and drought in the region. The study reveals the usefulness of the remotely sensed data of Landsat 8 satellite in estimating LST and drought changes in the KOSH area. This study also tried to assess the usefulness of Landsat 8 bands in deriving vegetation index and drought indices for monitoring drought in the KOSH region during three years (2013, 2018 and 2019).
THE CURRENT STATE OF RUSSIAN DRAFT BREED POPULATION WITH THE ACCOUNT OF THE REQUIREMENTS OF THE MARKET
Authors: Борисова А.В.
Published: July 2024

Дана численность популяции лошадей русской тяжеловозной породы на современном этапе развития и в ретроспективе. Изложена краткая характеристика современного производящего состава.

It is given the number of the Russian Draft breed population at the present stage of development and in retrospective. A short description of the current breeding stock is presented.
REVIEW OF FOREIGN STUDIES CONCERNING BIOLOGICAL ROLE OF SELENIUM IN THE LIFE OF HORSES
Authors: Дубровин А.В.
Published: July 2024

В статье обобщён обзор знаний о селене, его содержании в окружающей среде и биологической значимости для организма. Рассмотрены основные последствия дефицита и избытка селена в рационе лошадей, а также способы решения данной проблемы.

The article summarizes the review of knowledge about selenium, its content in the environment and biological significance for the body. The main consequences of deficiency and excess of selenium in the diet of horses, as well as ways to solve this problem are considered.
AKHAL-TEKE BEFORE AND NOW. TWO PORTRAITS
Authors: Кузнецова Ю.Н.
Published: July 2024

Представлены результаты сравнения лучших жеребцов ахалтекинской породы XIX века с картин русских художников А.Б. Виллевальде (жеребец Сардар) и Н.Е. Сверчкова (жеребец Аад) с фотографическими изображениями современных жеребцов - лучших представителей этой породы. Для сравнения отбирались жеребцы разных временных периодов XX-XXI веков, сфотографированные в сходной позе. Учитывалась принадлежность к внутрипородному типу - основному (Сардар) и скаковому (Аад). Определены параметры, по каким изменился экстерьер ахалтекинской лошади в указанный период. Среди современных жеребцов полностью идентичного Сардару не обнаружилось. Ближе всех по многим признакам стоит к нему трехлетний жеребец Караоглан. В экспозиции музея имеется также художественное изображение другого ахалтекинского жеребца - серого Аада. Этому изображению наиболее наиболее близок из современных жеребцов Гахрыман 1975 г.р.

The results of comparison of the best stallions of the Akhal-Teke breed of the XIX century with the paintings of Russian artists A. B. Villevalde (Sardar stallion) and N. E. Sverchkova (Aad stallion) with photographic images of modern stallions - the best representatives of this breed. For comparison, stallions of different time periods of XX-XXI centuries were selected, photographed in a similar pose. Account of the belonging to intrabreed type - basic (Sardar) and the race (Aad). The parameters conformation changings of the Akhal-Teke horse during this period were determined.Among modern stallions it were not found stallions identical to the Sardar. The closest in many ways to it is a three year old stallion Karaoglan.In the exposition of the Museum there is also an artistic image 146of another Akhal-Teke stallion - grey Aad. The modern stallions Ghahraman ,1975, is the closest to this image.
THE QUALITY OF CRYOCONSERVATED SEMEN OF STALLIONS DEPENDING ON THE AGE
Authors: Науменкова В.А.
Published: July 2024

В старшем возрасте у жеребцов (17-22 года) снижается качество спермы. Доля жеребцов с низким качеством криоконсервированной спермы возрастает до 45 %. В этом возрасте, в отличие от других возрастов, возможна потеря оплодотворяющей способности криоконсервированного семени, в случае снижения подвижности и выживаемости спермиев после оттаивания на 25 % от нормативных значений.

The quality of semen has been decreasing in older stallions (17-22 years). The share of stallions with low quality of cryoconservated semen increases to 45 %. At this age, unlike other ages, it is possible to lose the fertilizing ability of cryoconservated semen in the case of reduced mobility and survival of sperm after thawing by 25 % of the normative values.
SEARCH FOR GENETIC ASSOCIATIONS WITH CRYORESISTANCE OF STALLION SEMEN
Authors: Кудинов А.А. , Дементьева Н.В. , Атрощенко М.М. , Мусидрай А.А. , Никиткина Е.В.
Published: July 2024

Проведена оценка 163 эякулятов от 100 жеребцов по качеству спермы после криоконсервации. Выбраны и генотипированы 96 жеребцов с высокой и низкой криоустойчивостью спермы. В результате GWAS-анализа найдена 101 значимая ассоциация.

The evaluation of 163 ejaculates from 100 stallions on the quality of semen after cryoconservation was carried out. 96 stallions with high and low semen cryostability were selected and genotyped. As a result, the GWAS-analysis of 101 significant associations was found.
PRODUCTIVE HORSE BREEDING IN CENTRAL RUSSIA AS ONE OF THE WAYS TO RESTORE MASS HORSE BREEDING AND USE OF HORSES
Authors: Суходольская И.В.
Published: July 2024

В статье рассмотрена возможность увеличения потенциала продуктивного коневодства в нетрадиционных для него Центральных Российских регионах, а также некоторые факторы, его стимулирующие и тормозящие.Продуктивное коневодство в данном контексте рассматривается как один из способов восстановления массового коневодства, заполнения территорий и восстановления потребительского рынка как первой ступени развития рынка следующего уровня - эффективной продажи высококлассных племенных, спортивных лошадей и зрелищ.

The article considers the possibility of increasing the potential of productive horse breeding in non-traditional regions of Central Russia, as well as some factors that stimulate and inhibit it.In this context, productive horse breeding is considered as one of the ways to restore mass horse breeding, fill the territories and restore the consumer market as the first stage of development of the market of the next level - the effective sale of high-quality horses for breeding, sports and shows.
EFFICIENCY OF STALLMOTION’S SPERM CRYOPRESERVATION IN BIG AND SMALL VOLUMES BY KHARKOV TECHNOLOGY
Authors: Евсюкова А.А. , Медведева Д.А. , Шабанова А.А. , Ткачева О.Л. , Ткачев А.В.
Published: July 2024

В статье представлены результаты изучения физиологических особенностей спермы жеребцов в зависимости от формы и объема спермодоз. Зарубежные методы замораживания спермы жеребцов, быков и самцов других видов предусматривают фасовку и замораживание спермы в виде пайет объемом 0,5 мл в парах сжиженного азота при температуре минус 130 °С. Кроме пайет объемом 0,5 мл возможно применение пайет объемом 0,25 мл, которые тоже охлаждаются в парах азота при температуре минус 130 °С. Целью настоящего исследования было изучение физиологических характеристик разделенных эякулятов жеребцов после криоконсервирования в зависимости от формы и объема спермодоз. Каждый эякулят делили на 6 равных частей и расфасовывали в пайеты 0,5 мл, в пайеты 0,25 мл, облицованные гранулы 0,5 мл, облицованные гранулы 0,25 мл, открытые гранулы 0,25 мл и шприц-тубы 5 мл. Несмотря на относительно больший объем спермы в шприц-тубе (5 мл) скорость снижения температуры была близка к таковой внутри пайет и находился в пределах норм, которые считаются оптимальными для получения показателей спермы высокого качества после деконсервации.Средняя скорость для спермы в шприц-тюбах в диапазоне от 0 до минус 10 °С составляла около 4,12 °С/мин, от минус 10 °С до минус 80 °С -около 21,25 °С/мин.

The article presents the results of studying the physiological characteristics of stallion sperm, depending on the shape and volume of sperm doses. Foreign methods of freezing sperm of stallions, bulls and males of other species provide for the packing 245and freezing of sperm in the form of a 0.5 ml plow in pairs of liquefied nitrogen at a temperature of minus 130 °C. In addition to a volume of 0.5 ml, it is possible to use a volume of 0.25 ml, which are also cooled in nitrogen vapor at a temperature of minus 130 °C. The aim of this article was to study the physiological characteristics of the separated ejaculates of stallions after cryoconservation, depending on the shape and volume of semen doses. Each ejaculate was divided into 6 equal parts and packaged in 0.5 ml paillettes, 0.25 ml in paillettes, 0.5 ml lined granules, 0.25 ml lined granules, 0.25 ml open granules and 5 ml syringe tubes. Despite the relatively larger volume of sperm in the syringe tube (5 ml), the rate of temperature decrease was close to that inside the plow and was within the limits that are considered optimal for obtaining high-quality sperm indicators after deconservation. The average speed for sperm in syringes in the range from 0 to minus 10 °C was about 4.12 °C/min, from minus 10 °C to minus 80 °C - about 21.25 °C/min.
Correlation between factors of breeding value of sires and use intensity
Authors: Калинкина Г.В. , Орлова Ю.А. , Крешихина В.В.
Published: July 2024

Выявлены факторы племенной ценности производителей, определяющие продолжительность племенного использования жеребцов, количество полученного приплода и уровень отбора их сыновей в производящий состав.

The factors of breeding value of sires determining duration of breeding career of stallions, quantity of the received offspring and intensity of selection of their sons for breeding stock.
Aritmogén jobb kamrai cardiomyopathia sinuscsomó-diszfunkcióval
Authors: Gergely G. Tamás , Bánfi-Bacsárdi Fanni , Pilecky Dávid , Szűcs Gábor , Hajkó Erik , Hámory Eszter , Som Zoltán , Tóth Attila , Muk Balázs , Borbás Sarolta
Published: July 2024

Bevezetés: Az Európai Kardiológus Társaság 2023-as Cardiomyopathia Irányelve a cardiomyopathiák fenotípus-alapú megközelítését javasolja, a diagnózis felállításában a komplex, multimodális, multidiszciplináris kivizsgálás, multiparametrikus szemlélet kiemelt szerephez jut. Eset: Egy 70 éves férfi esetét mutatjuk be, akinek bőrgyógyászati műtét előtti preoperatív vizsgálata során az EKG-n nem tartós kamrai tachycardiát (nsVT), transthoracalis echokardiográfián tágult jobb kamrát észleltek. Kardiológiai kivizsgálása során jelentős bradycardiát okozó sinuscsomó-diszfunkció mellett a jobb kamrai aritmogén cardiomyopathia (ARVC) EKG-kritériumai teljesültek (negatív T-hullámok V1-V3-ban, epszilon-hullám jelenléte), monitorozása során recidív nsVT-ket észleltünk. A jobb kamrai funkció és morfológia vizsgálatára szív-MR-vizsgálatot végeztünk, amely dilatált jobb kamrát igazolt (végdiasztolés volumen testfelszínre normalizálva 155 ml/m2 ), azonban falmozgászavar nem volt észlelhető. A jobb kamrai dilatáció hátterében felmerülő pitvari szeptumdefektust transoesophagealis szívultrahang-vizsgálattal kizártuk. Összességében a 2010-es Task Force Kritériumok közül teljesülő 3 major kritérium alapján az ARVC diagnózisa felállítható volt. Mindezek után, tekintettel a sinuscsomó-diszfunkcióra és az ARVC diagnózisára, primer prevenciós DDD-ICD implantáció mellett döntöttünk, amely után hosszú távú gyógyszeres kezelésként béta-blokkoló-terápiát alkalmaztunk. Következtetés: Az ARVC ritka strukturális szívizombetegség, amelynek diagnosztizálása gyakorta komoly kihívást jelent, amelyben a klinikai gyanújelek, „red flag”-ek (funkcionális és morfológiai eltérések, elektrofiziológiai jellegzetességek) keresése stratégiai fontosságú.
A szívinfarktus miatt kezelt betegek ellátásának és prognózisának fontosabb adatai : Nemzeti Szívinfarktus Regiszter 2023
Authors: Jánosi András
Published: July 2024

A Nemzeti Szívinfarktus Regiszter (NSZR) éves beszámolóját hagyományosan a Cardiologia Hungaricában közöljük. 2023-ban 13 451 infarktusos eseményt regisztráltunk (STEMI 47,6,%, NSTEMI 52,4%), amely az összes, NEAK által finanszírozott kezelés 88,5%-a. A revaszkularizáció során primer perkután koronáriaintervenció (PPCI) történt a STEMI-, illetve NSTEMI-betegek 85,6%, illetve 63,4%-ánál. Sajnálatos, hogy a korábbi évekhez hasonlóan továbbra is túl későn kerül sor az érmegnyitásra. A STEMI-betegeknél a teljes iszkémiás idő (a panasz kezdete és az ér megnyitása között eltelt idő) mediánja 265 perc. A betegek 45,8%-ánál történt meg a revaszkularizáció 4 órán belül, és minden tizedik betegnél (10,6%) 24 óra vagy annál hosszabb idő telt el az ér megnyitásáig. NSTEMI-ben a betegek 61%-ánál került sor a PCI beavatkozásra 24 órán belül. A szívkatéterezés mindkét betegcsoportban szinte kizárólag radiális behatolásból történt (94,5%, illetve 95,8%). A stentek 94,2, illetve 92,8%-a gyógyszerkibocsájtó stent volt. A kórházi kezelés során szinte minden beteg részesült a másodlagos prevenció szempontjából fontos gyógyszeres kezelésben, illetve ennek folytatására javaslatot kaptak. Az akut szak után a STEMI-betegek 10,9%-a, az NSTEMI-betegek 5,8%-a került rehabilitációs intézetbe. A STEMI-betegek 30 napos halálozása 14,7% volt, ha primer PCI történt, akkor 11,6%. NSTEMI-betegeknél 10,1%, illetve 6,7%. Elemeztük centrumok szerinti bontásban a koronarográfia, valamint a PCI alkalmazásának gyakoriságát, illetve a 30 napos halálozást. Az összehasonlítás minden vizsgált tényező esetén jelentős különbségeket igazolt, ennek további vizsgálata indokolt.
Spectroscopic Signatures of Phonon Character in Molecular Electron Spin Relaxation
Authors: Kazmierczak Nathanael , Oyala Paul , Hadt Ryan
Published: July 2024

Spin-lattice relaxation constitutes a key challenge for the development of quantum technologies, as it destroys superpositions in molecular quantum bits (qubits) and magnetic memory in single molecule magnets (SMMs). Gaining mechanistic insight into the spin relaxation process has proven challenging owing to a lack of spectroscopic observables relative to the many degrees of freedom involved. Here, we use pulse electron paramagnetic resonance (EPR) to profile systematic changes in the spin relaxation anisotropy as a function of temperature for two Cu(II) coordination compounds. For randomly-oriented powder samples, large anisotropy changes arise between 20 and 50 K that delineate multiple regimes of relaxation for each molecule studied. Local mode fitting of the average T1 value fails to consistently extract the anisotropy regime crossover. Single-crystal T1 anisotropy experiments reveal a surprising difference between the symmetry of the spin relaxation tensor in these two regimes. In the high-temperature regime, spin relaxation is fastest and slowest along the principal axes of the molecular g-tensor, which obeys the symmetry of the molecular point group. In the low-temperature regime, spin relaxation is fastest and slowest along arbitrary directions of the g-tensor, instead responding to the crystal packing. We interpret this switch as arising from a change in the localization of the phonons driving spin relaxation at different temperatures, consistent with delocalized lattice phonons in the low-temperature regime and localized molecular vibrations in the high-temperature regime. Variable-temperature T1 anisotropy thus provides a unique method of interrogating the character of nuclear motions causing the spin relaxation process.
External Acidity as Performance Descriptor in Polyolefin Cracking using Zeolite-Based Materials
Authors: Rejman Sebastian , Reverdy Zoé M. , Bör Zeynep , Louwen Jaap N. , Rieg Carolin , Dorresteijn Joren M. , van der Waal Jan-Kees , Vogt Eelco T. C. , Vollmer Ina , Weckhuysen Bert M.
Published: July 2024

Thermal pyrolysis is gaining industrial adoption to convert large volumes of plastic waste into hydrocarbon feedstock. However, it suffers from a high reaction temperature and relatively low selectivity. Utilizing a catalyst in the process, moving from thermal pyrolysis to catalytic cracking could help overcome both challenges. In order to develop efficient catalyst materials for this process, understanding structure-composition-performance relationships is critical. In this work, we show that in contrast to cracking of small molecules, plastic cracking activity using ultrastable zeolite Y materials does not depend on the bulk Brønsted acid site content, but rather on the concentration of acid sites located on the outer surface and in mesopores. This external acidity, however, fails to capture all the observed performance trends. Detailed kinetic experiments revealed that the scaling of the reaction rate with the catalyst loading differs drastically between highly similar catalyst materials. More specifically, doubling the catalyst loading leads to doubling of the reaction rate for one material, while for another it leads to more than fivefold increase. When very bulky reactants, such as polyolefins, are converted over microporous catalysts, structure-composition-performance relationships established for smaller molecules need to be revisited.
Unexpected Two-Stage Swelling of Weak Polyelectrolyte Brushes with Divalent Counterions
Authors: Beyer David , Holm Christian
Published: July 2024

We use particle-based, coarse-grained simulations to study the influence of divalent counterions on a weak polyelectrolyte brush. Our simulations show a profound influence of even small concentrations of divalent salt on the titration behavior of the brush, which is shown to be a combined effect of electrostatic interactions and the Donnan effect. Furthermore, we examine the partitioning of mono- and divalent counterions into the brush. We demonstrate the preferred uptake of divalent ions by the brush, which is further enhanced by electrostatic correlation effects. Finally, our simulations reveal a hitherto unobserved two-stage swelling of the brush as a function of the pH in the presence of divalent salt. This phenomenon arises as a consequence of charge regulation and ion partitioning.
A new sensitive and robust method development for estimation of tolcapone and quinapril in the bulk and formulations
Authors: Bollavaram Sireesha , Shahida Bee
Published: July 2024

Tolcopone and Quinapril are anti-hypersensitive drugs and, in combined dosages, are effective in managing hypertension. The RP-HPLC method was developed using OPA and Acetonitrile in 50:50 v/v as Mobile phase and 250*4.6mm, 5µ RP-HPLC column measured with a wavelength of 240nm. The HPLC system was fixed with a flow rate of 1.0ml/min; Both drugs, TOLCO and QUINA, were successfully detected at 2.153 and 3.203 min, respectively. The validation of the method as per ICH Linearity r2 lies at 0.999, and Precision, system suitability, and selectivity RSD values are within permissible limits. The accuracy of the process was found to be 99.73 and 99.52 for TOLCO and QUINA, respectively. The LOD 0.72 and 0.3 µl/ml and LOQ 0.84 and 0.13 µl/ml. The robustness and degradation studies show that the selected method is acceptable per the Guidelines.Bottom of Form
A documentação museológica de um patrimônio cultural da saúde: o caso da coleção museológica do Museu do Instituto Evandro Chagas
Authors: Silva Giselle Santos , Elian dos Santos Paulo
Published: July 2024

Este artigo tem por objetivo apresentar o modelo de documentação museológica adotado no Museu do Instituto Evandro Chagas – MEV, na cidade de Belém, PA, discutindo os princípios e procedimentos normativos que o orientam. Para tanto, a investigação analisa o tratamento da documentação museológica voltada para acervos de ciência & tecnologia. Por fim, apresenta o processo de formação da coleção do Museu do Instituto Evandro Chagas - MEV, a fim de compreender o papel dos objetos vinculados a temática da saúde, na construção da memória institucional e na preservação do testemunho dos processos científicos e do desenvolvimento tecnológico.
Perspectivas de Documentação Museológica: competências, formações, experiências e reflexões
Authors: Da Silva Anna Paula , Mendonça Elizabete de Castro , Ballardo Luciana Messeder
Published: July 2024

Apresentação do Dossiê Perspectivas de Documentação Museológica: Competências, Formações, Experiências e Reflexões. Os artigos disponíveis neste dossiê apresentam discussões plurais sobre a documentação no âmbito da formação em Museologia e na atuação profissional, além de apresentar experiências sobre a prática documental.
Pengaruh Instrumen Kebijakan Makroprudensial Terhadap Pertumbuhan Kredit Bank Umum di Indonesia
Authors: Audya Putri Sabrina
Published: July 2024

Penyaluran kredit  bank mempunyai dampak terhadap perekonomian. Dalam menjaga stabilitas ekonomi kebijakan moneter saja tidak cukup, sehingga diperlukannya kebijakan makroprudensial. Penelitian ini bertujuan untuk melihat pengaruh kebijakan makroprudensial yaitu Rasio Intermediasi Makroprudensial (RIM) terhadap kredit  bank umum di Indonesia pada saat perekonomian sedang mengalami kontraksi akibat pandemi Covid-19. Penelitian ini juga menggunakan variabel faktor internal bank seperti Capital Adequacy Ratio (CAR), Loan to Deposit Ratio (LDR) dan Total Aset. Penelitian ini menggunakan data 60 bank umum dengan menggunakan teknik estimasi Panel Least Square (PLS) dan menggunakan data kuartalan periode tahun 2013Q1 hingga 2021Q4. Hasil dari penelitian ditemukan RIM berpengaruh positif dan signifikan terhadap kredit. Untuk variabel internal bank CAR, LDR dan Total Aset berpengaruh signifikan terhadap kredit. Total aset (ukuran bank) memiliki pengaruh positif dan signifikan terhadap kredit bank. CAR memiliki pengaruh negatif dan signifikan terhadap kredit bank. LDR memiliki pengaruh positif dan signifikan terhadap kredit bank.
Estimasi Biaya Ekonomi Pengembangan Pembangkit Listrik Tenaga Mikro Hidro (PLTMH) di Provinsi Jawa Barat
Authors: Faza Muhammad Abigail , Yudistia D. Arnoldus
Published: July 2024

Ketersediaan energi listrik merupakan keunggulan dalam pembangunan berkelanjutan. Pembangunan Pembangkit Listrik Tenaga Mikro Hidro di Provinsi Jawa Barat merupakan upaya alternatif penyediaan sumber energi terbarukan yang ramah lingkungan dalam mengatasi keterbatasan distribusi energi listrik oleh PLN. Pembangunan PLTMH di Jawa Barat ditujukan untuk daerah pedesaan yang belum memiliki jaringan distribusi atau mengalami masalah distribusi listrik. Oleh karena itu, penelitian ini bertujuan untuk mengetahui berbagai dampak yang ditimbulkan dari pembangunan PLTMH dan menghitung biaya ekonomi dari berbagai biaya yang timbul dari PLTMH. Dalam penelitian ini, metode penelitian yang digunakan adalah valuasi ekonomi. Perhitungan penelitian menunjukkan bahwa total biaya pribadi adalah Rp. 66.819.047.098 biaya terdiri dari biaya konstruksi sebesar Rp. 60.298.187.145, dan biaya operasional dan pemeliharaan sebesar Rp. 6.520.859.953, sedangkan biaya sosial sebesar Rp. 626.400.000.
Potensi Biomassa Dalam Transisi Energi di Indonesia
Authors: Primadanty Ria Putri
Published: July 2024

Energi biomassa merupakan asset untuk transisi energi di Indonesia. Transisi energi akan terjadi dari perekonomian energi non fosil ke energi biomassa. Penelitian ini membahas tentang ketersediaan ekonomi energi biomassa di Indonesia, hambatan-hambatan yang perlu diselesaikan, serta kebijakan pemerintah terkait biomassa di Indonesia. Penelitian ini dilakukan dengan menggunakan kajian pustaka dari sumber-sumber terkait yang diterbitkan antara tahun 2009-2020. Hasil penelitian menunjukkan bahwa energi biomassa di Indonesia memiliki potensi sebesar 146,7 ton per tahun. Dari keseluruhan energi primer, pasokan energi biomassa dikatakan sebagai pasokan terbesar kedua setelah energi minyak bumi. Energi biomassa dapat dimanfaatkan sebagai energi listrik dan gas. Untuk energi listrik biomassa saja, per tahunnya berpotensi sebesar 24,46 GW. Transisi ini ditargetkan akan terjadi sampai dengan tahun 2050.
Development of an Anti-Acne Facial Wash Gel With Cassia alata L. Leaf Extract
Authors: Meirista Indri , Mariska Ruri Putri , Jannah Miftahul
Published: July 2024

Acne is a skin disease that is often encountered. Acne can be caused by various factors, including bacterial infection. To prevent acne, keep facial skin clean using facial wash. Using facial wash made from synthetic substances can cause more significant side effects than natural ingredients, so research is needed on natural ingredients that can be used as anti-acne agents. One natural ingredient that has antibacterial activity is ketepeng leaf (Cassia alata L.). This research aims to formulate a facial wash gel preparation from ketepeng leaf extract and test its antibacterial activity against Staphylococcus aureus bacteria. This research is experimental research starting from making extracts, dosage formulation, evaluating the physical properties of the dosage (stability test, organoleptic test, homogeneity test, pH test, viscosity test, spreadability test, and foamability test), skin irritation test, hedonic test and antibacterial activity against Staphylococcus aureus bacteria. The research results showed that the inhibition zone produced by formula 1 was 9,73mm, formula 2 was 10,33mm, and formula 3 was 13,18mm. This research concludes that Ketepeng leaf can be used as an active ingredient in anti-acne facial wash gel preparations because the Ketepeng leaf extract facial wash gel preparation meets the requirements for evaluating good physical properties and has antibacterial activity against Staphylococcus aureus bacteria in each formula.
Burtas Uterus Involution Phantom Development
Authors: Novianti Lily , Komariah Nurul , Asmalinda Wita
Published: July 2024

One way to diagnose retained placenta is by palpating the uterus to confirm uterine involution. Midwives must have these competencies. One effort to improve student competency is the availability of complete facilities and infrastructure. Currently, the phantom used does not describe in detail the process of uterine involution according to postpartum physiology. Detailed and detailed phantoms are very expensive. This research aims to develop a burtas (paper pulp) uterus involution phantom. It is a phantom covering several parts: the pelvis, abdomen, uterus, and external genitalia. The research was done in the laboratory of the Midwifery Department, Health Polytechnic, Ministry of Health, Palembang, June-October 2023. Research Subjects were DIII Midwifery Study Program students by purposive sampling in small groups of ten people and large groups of 20 people. This research uses a development research design known as Research and Development (R&D). Research and development aim to develop an existing product that can be tested for feasibility and effectiveness. The stages are potential and problems, data collection, product design, design validation, design revision, product trials, product revisions, usage trials, product revisions, and production. The burtas uterine involution phantom feasibility test results were declared very feasible by media experts with a score of 100%. Material expert with a score of 100%, Students 88.03%. The developed uterine involution phantom can be used as a phantom or alternative teaching aid for examining uterine involution in midwifery and breastfeeding care practicums.
Quality of Life Patients HIV Based on Characteristic, Duration of Diagnosis, and Types Antiretroviral (ARV)
Authors: Amelia Iftikar Salma , Rahayuwati Laili , Harun Hasniatisari , Ibrahim Kusman , Prawesti Ayu , Pramukti Iqbal
Published: July 2024

Human Immunodeficiency Virus (HIV) is a retrovirus that attacks the body's immune system, leading to an increase in morbidity and mortality rates in Indonesia. HIV can cause problems in both physical and emotional aspects, impacting the quality of life in daily activities. This study aims to determine the health-related quality of life of HIV patients based on characteristics, duration of diagnosis, and types of antiretroviral treatment at RSUD Sumedang. The research utilized a cross-sectional design with a population of HIV patients visiting the teratai clinic at RSUD Sumedang. Sampling was done using consecutive sampling, involving 71 respondents who met the inclusion criteria. Data analysis in this study utilized univariate analysis and bivariate analysis using chi-square. The univariate analysis results indicated that the majority of respondents had a good quality of life at 56.3%, measured using EQ-5D-5L, with the anxiety/depression domain being the one with the most issues. The results of bivariate analysis using chi-square showed no significant relationship between characteristics, duration of diagnosis, and types of antiretroviral treatment with the quality of life in HIV patients at RSUD Sumedang. It was concluded that the quality of life of HIV patients at RSUD Sumedang, measured using EQ-5D-5L, is mostly good. The domain of anxiety/depression is the most problematic.
Lessons learned from a tech-enhanced medical english class: Changes, experiences and reflections
Authors: Raside Dag-Akbas
Published: July 2024

The current research is based on two educational changes introduced in an English class for prospective medical doctors. These changes involved a shift in the educational process: first, adopting an English for Medical Purposes (EMP)- based approach that emphasizes communicative skills, designed following a comprehensive needs assessment due to its special focus on EMP. Second, the class was moved to an online platform, delivered both synchronously and asynchronously. Grounded in qualitative case study research, this study aims to explore the perceived usefulness of implementing such an EMP-based English class in an electronic delivery mode by examining the reflections, evaluations, and experiences of English lecturers throughout the course. Evidence was gathered from various sources, including weekly meetings, mobile group chats, informal telephone interviews, and online journals. Overall, the findings indicated that while the change in the program's course content, with its focus on communicative competence in EMP, was highly appreciated, the electronic delivery mode specifically its new educational environment received relatively less positive feedback. Lessons learned from this experience within the context of EMP may benefit future curriculum designers, course teachers, and other stakeholders interested in similar educational innovations.
Effective Teaching Methods in Physical Education Classes: A pilot study implementing a new survey for teachers
Authors: Kelmendi Diellza ,   Kosovo Olympic Academy, Kosovo Olympic Committee, Pristina, Kosovo, Dedi Tringa ,   Kosovo Pedagogical Institute, Pristina, Kosovo
Published: July 2024

Physical education (PE) classes for children play a crucial role in promoting physical activity and healthy lifestyle. The PE in the Kosovo primary schools, together with its teaching and organizational issues have long been a key topic of political, sport and scientific debate. However, the various actions carried out so far have not been enough to recognize contents and methods of PE correctly oriented in an educational way. The aim of the study is to highlight the latest method and strategies of the teachers, and the new curriculum used in the field of PE for better learning and developing health among children through physical activity. The research involved (n = 100) PE teachers from Kosovo public schools. All teachers are from Kosovo primary schools, classes VI-IX, with an average of 16 years of work experience. Data was collected using questionnaire by an online survey. The learning methods mostly applied are: practical learning method (96%), teaching through lectures (79%), interactive method (72%), effective teaching method (66%), learning through certain goals (47%). The factors that influence the effective use of teaching strategies are: infrastructure and equipment (94%), teacher skills (89%), competitive activities among children (57%), and children’s desire for physical and sports activities (46%). The factors that can influence the increase in the effectiveness of teaching strategies are: the addition of teaching hours (92%) teacher trainings (84%) and curricular improvements (78%). Teaching methods help teachers to have an effective communication with students, clear instructions, demonstrations, and techniques being taught.
Experimental Studies of Schiff Base (E)-4-methoxy-2-(((2-phenoxyphenyl)imino)methyl) phenol Compound with Various Spectroscopic Methods
Authors: Güzel E. , Çoruh U. , Duteanu N. , Cıcek C. , Agar E. , Vazquez-Lopez E.M. , Yavuz M.
Published: July 2024

Schiff-based compounds, which represent an important class in the field of organic compounds, form the basis of this research article. This research article aims to investigate the synthesized compound (E)-4-methoxy-2-(((2-phenoxyphenyl) imino) methyl) phenol using experimental methods.FT-IR, UV-Vis, 13C and 1H Nuclear Magnetic Resonance (NMR) Spectroscopy and X-ray diffraction methods were used to elucidate the structural properties of the compound synthesized at the end of chemical processes. The structure solution was carried out from the data obtained as a result of X-ray analysis. According to these results, one of the two compounds in the asymmetric cell completed their formation in the enol-imine form and the other in the keto-amine form. This structural situation, which is rare in the literature, was supported and explained by FT-IR, 13C and 1H Nuclear Magnetic Resonance (NMR) spectroscopy studies.According to the results obtained as a result of UV-Vis spectroscopy, the structure revealed that the enol-imine form was dominant. The reasons for this situation were explained.
Pengembangan Model Persediaan dengan Penurunan Harga Sementara dari Pemasok: Studi Kasus pada Toko Kain X
Authors: Rikardo Cherish , Pratiwi Loren , Koernia Nadia
Published: July 2024

Toko X merupakan sebuah perusahaan ritel di Kota Bandung yang bergerak di bidang industri kain. Toko X seringkali mendapatkan penurunan harga sementara dari pemasok. Penurunan harga ini dimanfaatkan oleh Toko X dengan membeli kain sesegera mungkin dan dalam jumlah yang lebih banyak dari biasanya. Persediaan yang lebih banyak menyebabkan adanya penambahan biaya penyimpanan dan semakin lama stok kain keluar dari gudang. Toko X ingin mengurangi waktu penyimpanan kain dengan menetapkan harga jual yang dapat memberikan profit optimal. Penelitian ini bertujuan untuk mengembangkan model persediaan pada periode penurunan harga sementara dari pemasok. Pengembangan model dilakukan dengan mempertimbangkan adanya diskon yang diberikan kepada konsumen pada periode yang terbatas. Parameter yang digunakan dalam pengembangan model terdiri dari harga jual kain, besaran penurunan harga sementara dari pemasok, biaya pembelian kain, biaya penyimpanan per unit, dan tingkat permintaan. Variabel keputusan yang digunakan dalam pengembangan model adalah besaran diskon dan jumlah kain yang terjual dengan harga reguler setelah diskon. Berdasarkan model matematika yang telah dirancang, diperoleh hasil bahwa adanya penurunan harga sementara dari pemasok, Toko X akan memesan sejumlah 59.069,96 yard kain. Kemudian, Toko X dapat menawarkan diskon sebesar 4,5% dengan harga jual kain sebesar Rp33.425,00 kepada konsumen agar waktu penyimpanan kain menjadi berkurang sebesar 20% menjadi elama 3,97 bulan danRp738.448.855,57.
Update of the list of qualified presumption of safety (QPS) recommended microbiological agents intentionally added to food or feed as notified to EFSA 20: Suitability of taxonomic units notified to EFSA until March 2024
Authors:   EFSA Panel on Biological Hazards (BIOHAZ), Koutsoumanis Konstantinos , Allende Ana , Alvarez‐Ordóñez Avelino , Bolton Declan , Bover‐Cid Sara , Chemaly Marianne , De Cesare Alessandra , Hilbert Friederike , Lindqvist Roland , Nauta Maarten , Nonno Romolo , Peixe Luisa , Ru Giuseppe , Simmons Marion , Skandamis Panagiotis , Suffredini Elisabetta , Cocconcelli Pier Sandro , Fernández Escámez Pablo Salvador , Maradona Miguel Prieto , Querol Amparo , Sijtsma Lolke , Suarez Juan Evaristo , Sundh Ingvar , Botteon Angela , Fulvio Barizzone , Correia Sandra , Herman Lieve
Published: July 2024

Abstract
The qualified presumption of safety (QPS) process was developed to provide a safety assessment approach for microorganisms intended for use in food or feed chains. In the period covered by this statement, no new information was found that would change the status of previously recommended QPS TUs. The TUs in the QPS list were updated based on a verification, against their respective authoritative databases, of the correctness of the names and completeness of synonyms. A new procedure has been established to ensure the TUs are kept up to date in relation to recent taxonomical insights. Of 83 microorganisms notified to EFSA between October 2023 and March 2024 (47 as feed additives, 25 as food enzymes or additives, 11 as novel foods), 75 were not evaluated because: 15 were filamentous fungi, 1 was Enterococcus faecium, 10 were Escherichia coli, 1 was a Streptomyces (all excluded from the QPS evaluation) and 48 were TUs that already have a QPS status. Two of the other eight notifications were already evaluated for a possible QPS status in the previous Panel Statement: Heyndrickxia faecalis (previously Weizmannia faecalis) and Serratia marcescens. One was notified at genus level so could not be assessed for QPS status. The other five notifications belonging to five TUs were assessed for possible QPS status. Akkermansia muciniphila and Actinomadura roseirufa were still not recommended for QPS status due to safety concerns. Rhizobium radiobacter can be recommended for QPS status with the qualification for production purposes. Microbacterium arborescens and Burkholderia stagnalis cannot be included in the QPS list due to a lack of body of knowledge for its use in the food and feed chain and for B. stagnalis also due to safety concerns. A. roseirufa and B. stagnalis have been excluded from further QPS assessment.
New developments in biotechnology applied to microorganisms
Authors:   EFSA Panel on Genetically Modified Organisms (GMO), Mullins Ewen , Bresson Jean‐Louis , Dewhurst Ian Crawford , Epstein Michelle M. , Firbank Leslie George , Guerche Philippe , Hejatko Jan , Moreno Francisco Javier , Naegeli Hanspeter , Nogué Fabien , Rostoks Nils , Sánchez Serrano Jose Juan , Savoini Giovanni , Veromann Eve , Veronesi Fabio , Cocconcelli Pier Sandro , Glandorf Debora , Herman Lieve , Jimenez Saiz Rodrigo , Ruiz Garcia Lorena , Aguilera Entrena Jaime , Gennaro Andrea , Schoonjans Reinhilde , Kagkli Dafni Maria , Dalmay Tamas
Published: July 2024

Abstract
EFSA was requested by the European Commission (in accordance with Article 29 of Regulation (EC) No 178/2002) to provide a scientific opinion on the application of new developments in biotechnology (new genomic techniques, NGTs) to viable microorganisms and products of category 4 to be released into the environment or placed on the market as or in food and feed, and to non‐viable products of category 3 to be placed on the market as or in food and feed. A horizon scanning exercise identified a variety of products containing microorganisms obtained with NGTs (NGT‐Ms), falling within the remit of EFSA, that are expected to be placed on the (EU) market in the next 10 years. No novel potential hazards/risks from NGT‐Ms were identified as compared to those obtained by established genomic techniques (EGTs), or by conventional mutagenesis. Due to the higher efficiency, specificity and predictability of NGTs, the hazards related to the changes in the genome are likely to be less frequent in NGT‐Ms than those modified by EGTs and conventional mutagenesis. It is concluded that EFSA guidances are ‘partially applicable’, therefore on a case‐by‐case basis for specific NGT‐Ms, fewer requirements may be needed. Some of the EFSA guidances are ‘not sufficient’ and updates are recommended. Because possible hazards relate to genotypic and phenotypic changes introduced and not to the method used for the modification, it is recommended that any new guidance should take a consistent risk assessment approach for strains/products derived from or produced with microorganisms obtained with conventional mutagenesis, EGTs or NGTs.