bluuebunny/crossref_metadata_2025 huggingface dataset:
Differential expression of LOC441666 in amyotrophic lateral sclerosis.
Authors: Mamoor Shahan
Published: August 2022

Neurodegenerative diseases that affect the motor neurons, including amyotrophic lateral sclerosis (ALS), have little treatment options and are generally rapidly fatal (1, 2). We harnessed the power of unbiased, whole transcriptome differential gene expression analysis, utilizing primary patient cells and tissues to discover genes whose expression defines sporadic ALS using published data (3, 4). We found significant differential expression of LOC441666, encoding zinc finger protein 91 pseudogene, in primary fibroblasts of patients with sporadic ALS (SALS). LOC441666 transcript was present at significantly lower levels in SALS patient fibroblasts as compared to control, non-diseased fibroblasts. These analyses will begin to define the transcriptional landscape of sporadic ALS.
Medical 3D Printing, Intellectual Property and Regulation
Authors: Daly Angela
Published: August 2022

This chapter gives an overview of applicable legal frameworks to the main uses of 3D printing in medicine. In particular, medical device regulation and intellectual property are explored. 3D printing is not an unregulated field, but there can be ambiguities about how particular legal frameworks, developed in a pre-3D printing era, can apply. Questions also arise about whether these frameworks need to be changed to better facilitate desirable uses of 3D printing and protect against undesirable uses. This chapter presents some of these debates, and gives a summary of legal issues those using 3D printing in the medical field need to consider, focussing on intellectual property and medical device regulation.
Differential expression of C1QTNF2 in amyotrophic lateral sclerosis.
Authors: Mamoor Shahan
Published: August 2022

Neurodegenerative diseases that affect the motor neurons, including amyotrophic lateral sclerosis (ALS), have little treatment options and are generally rapidly fatal (1, 2). We harnessed the power of unbiased, whole transcriptome differential gene expression analysis, utilizing primary patient cells and tissues to discover genes whose expression defines sporadic ALS using published data (3, 4). We found significant differential expression of C1QTNF2, encoding C1q and tumor necrosis factor-related protein 2, in primary fibroblasts of patients with sporadic ALS (SALS). C1QTNF2 transcript was present at significantly higher levels in SALS patient fibroblasts as compared to control, non-diseased fibroblasts. These analyses will begin to define the transcriptional landscape of sporadic ALS.
Chương 1 - TỔNG QUAN VỀ NGHIÊN CỨU KHOA HỌC - Introduction Research methodology on business and management contexts
Authors: Tung Dao Duy
Published: August 2022

Definition of Research, definition ofdevelopment, reasons for research, difference betweenresearch and development.
Can children be taught values using game designs? Insights from a neurophysiological experimental study with children
Authors: Rajyaguru Chirag , Sahni Pooja , Jain Manvi , Pandey Rohit , Kumar Jyoti
Published: August 2022

The economical and technological evolution has brought the situation where our attention is being targeted. Lots of creative professionals have been employed by commercial agencies to grab attention such as in a marketing space. On the other hand, there is a societal need to use the attentional resources for development of human values towards harmonious coexistence. Designers therefore have this twin responsibility to use creative processes to design such that it grabs attention towards one or the other direction. Today brain research is advancing at a rapid pace and it has a potential to provide insights into the value based decision processes within users as well as within designers. This paper reports neurophysiological study on value based decision in children during a game play. A visual story based interactive game was designed to elicit value-based decisions from children. Eighteen children (age group of 5 to 9 years) participated in the pilot study. The neurophysiological data was derived using an electroencephalography (EEG) device during the story-interaction. This paper reports findings on how the proposed design in this study can be implemented for eliciting specific values, and therefore be applicable in acting as a value-based education system for younger populations.
Merawat Mentalitas Pembangunan di Masa Pandemi
Authors: Saputro Agus
Published: August 2022

Keberhasilan sebuah pembangunan dapat diukur melalui pertumbuhan ekonomi masyarakat yang tinggi. Dilihat melalui produktivitasnya, yakni Produk Nasional Bruto (PNB/GNP), dan Produk Domestik Bruto (PDB/GDP). Untuk melihat realitas produktivitas rata-rata maka digunakanlah PNB/kapita/tahun atau PDB/kapita/tahun. Akan tetapi realitasnya di Indonesia ketimpangan ekonomi menjadi massalah yang konkrit. Sehingga rata-rata produktivitas tidak menjadi ukuran mutlak jika Indeks Gini (skala 0-1) mendekati 1, berarti ketimpangan ekonomi tinggi.Lepas dari itu pembangunan bukan hanya sekedar perhitungan produktivitas barang dan jasa, akan tetapi yang lebih penting adalah membangun mentalitas. Mentalitas menentukan produktivitas berkelanjutan sedangkan produktivitas belum tentu menentukan mentalitas pembangunan yang baik apalagi berkelanjutan. Sehingga merawat mentalitas pembangunan lebih penting daripada mengutamakan produktivitas barang, karena pembangunan yang baik tidak hanya memikirkan keuntungan ekonomi, tetapi mempertimbangkan aspek kemanusiaan dan masyarakat.
A network cross-cultural validation of the Parenting Sense of Competence between Aboriginal and Non-Aboriginal Australians
Authors: Santiago Pedro Henrique Ribeiro , Sawyer Alyssa , Hedges Joanne , Sawyer Michael , Jamieson Lisa
Published: August 2022

The Parenting Sense of Competence Scale (PSOC) is the worldwide most used instrument to measure parenting sense of competence worldwide. Considering that cultural differences influence parenting practices, the investigation of cross-cultural validity is required to ensure that PSOC scores can be compared among Aboriginal and non-Aboriginal Australians. To address this research gap, the current study employed network psychometrics to investigate the cross-cultural validity of the PSOC among Aboriginal and non-Aboriginal Australians. The study investigated: (1) measurement invariance; (2) item redundancy; (3) dimensionality; (4) model fit; (5) reliability; and (6) criterion validity. Data was from the South Australian Aboriginal Birth Cohort (SAABC; n=178) and eMums study (n=107). The findings indicated that, after accounting for item redundancy, a revised 14-item version of the PSOC displayed the two theoretical dimensions of Efficacy and Satisfaction. The revised 14-item PSOC also displayed excellent psychometric properties and was cross-culturally valid among Aboriginal and non-Aboriginal Australians.
The effect of incentivization on the conjunction fallacy in judgments: A meta-analysis
Authors: Yechiam Eldad , Zeif Dana
Published: August 2022

The conjunction fallacy is a classical judgment bias that was argued to be insusceptible to the positive effect of incentivization. We conducted a meta-analysis of the literature (n = 3,276) and found that although most studies did not report a significant effect of incentivization, the results across studies show a significant positive effect for incentivization, d = 0.19, with an odds ratio of 1.40 for answering correctly when incentivized. The effect was relatively smaller when examining absolute differences in the probability of correct judgment, implying that it is partly driven by studies with low baseline performance. Additionally, most of the variance between studies was estimated to be due to random noise. These findings join those of other judgment-bias studies to suggest a small but nevertheless robust debiasing effect of incentivization. The findings further suggest cautious interpretation of moderators and null results in light of the extreme variance between individual study results given a small effect size in the population.
Rethinking Online Harm: A Psychological Model of Contextual Vulnerability
Authors: Cork Alicia , Smith Laura G. E. , Ellis David Alexander , Stanton Fraser Danaë , Joinson Adam
Published: August 2022

“Online harm” is an umbrella term used to refer to any online activities which may cause harm to individuals or society. Psychological research is integral to the study of individual harms, such as misinformation, cyberbullying or radicalisation, however psychological theory is notably lacking from broader conceptualizations of online harm. Following the PRISMA guidelines, we systematically reviewed 46 taxonomies and typologies of online harm and risk to assess how harm is currently conceptualised. We find that there are four main challenges associated with how harm is currently classified; (i) there are notable semantic conflations between causes of harm and resultant harmful outcomes, (ii) current conceptualisations of harm are unable to anticipate future harms, (iii) contextual features are integral for understanding when harm occurs and, (iv) online risks are often cascading and lead to non-linear harmful outcomes. Based on these four limitations, we propose a novel conceptualisation of online harm which integrates psychological theory with a systems-safety approach in order to understand the precise conditions under which vulnerability to harm occurs. We discuss the value of psychological theory for understanding the mechanisms that lead to vulnerability, and we propose that a psychological approach is best able to anticipate and understand potential future harms. Finally, we provide a case study of how our psychological model can be used to organise and understand the current literature.
Anatomical Risk Factors of Nerve Injuries Following Surgical Removal of Mandibular Third Molar
Authors: Shrestha Reena K. , Shrestha Dipti , Sakya Pranay Ratna , Khadka Dhiraj , Shrestha Rakshya , Shrestha Kanchan
Published: August 2022

Introduction: Surgical removal of the mandibular third molar has its own set of complications. The mandibular impacted teeth are in proximity to the Inferior Alveolar Nerve (IAN), Buccal Nerve, and Lingual Nerve (LN). Therefore, each of these nerves is always at risk of injury during extraction.
Objectives: This study was to evaluate the anatomical risk factors of nerve injury after the surgical extraction of mandibular third molars in patients visiting the department of oral and maxillofacial surgery of People’s Dental College and Hospital.
Methods: This prospective study was conducted with 315 participants who presented with a mandibular third molar impaction and underwent Intraoral Periapical Radiograph (IOPAr), panoramic radiograph, as well as Cone Beam, Computed Tomography (CBCT). CBCT was done in those patients in which the mandibular third molar was in close contact with the mandibular canal.
Results: Collected data from 315 patients showed that the incidence of Inferior alveolar nerve (IAN) and lingual nerve(LN)injury was 0.31%. Of which one had mesioangular class B, level II type of impaction in 17year male and the other had horizontal class C, level II type of impaction in 47year female respectively. In both cases, the tooth was lingually placed in relation to IAN.
Conclusions: Various factors are responsible for nerve injury after the removal of the mandibular third molar. In our study, the incidence of nerve injury to IAN and LN was comparatively low and the most common risk factor was angulation and anatomical position of the impacted mandibular third molar.
Morbidities and its Immediate Outcome in Newborns Born Through Mothers with Gestational Diabetes Mellitus
Authors: Bhatta Mukesh , Aneja Vikas
Published: August 2022

Introduction: Gestational Diabetes mellitus is associated with a significant risk of maternal and neonatal morbidity.
Objective: The objective of this study was to assess the different morbidities and their immediate outcome in newborns born to mother with gestational diabetes mellitus.
Methods: A descriptive cross-sectional study was done among 349 inborn neonates born to mothers with gestational diabetes mellitus, at the Department of Pediatrics and Adolescent Medicine, B.P. Koirala Institute of Health Sciences. The informed written consent and ethical approval were taken. The different socio-demographic & clinical parameters of the mothers and neonates were taken. The data was analyzed using relevant statistical tests.
Results: Out of the total 11977 deliveries, there were 431 (3.6%) deliveries of mothers with gestational diabetes mellitus. More than half of the neonates were male. The mean birth weight and gestational age of the neonates were 39±2 weeks and 3100 ± 570 gram respectively. Sixty-four (18.3%) neonates had some form of morbidity. The three major morbidities in the neonates were small for gestational age (n=39, 11.2%), preterm birth (n=34, 9.7%) and neonatal hyperbilirubinemia (n=24, 6.9%). The incidence of macrosomia, hypoglycemia, hypocalcemia, polycythemia, cardiac defects, and gross congenital anomalies were 21 (6%), 22 (6.3%), six (1.7%), one (0.3%), eight (2.3%) and two (0.6%) respectively. Similarly, 22 (6%) neonates needed admission, out of which 16 (4.6%) recovered and got discharged, while six (1.4%) expired.
Conclusions: The major morbidities associated with neonates born to mothers with gestational diabetes mellitus were small for gestational age, prematurity, neonatal hyperbilirubinemia, and hypoglycemia.
Formulation and in-vitro Evaluation of Oro-dispersible tablets of Indomethacin
Authors: Pokhrel Gopal , Kunwar Ganga , Rai Jun Devi , Thapa Sheela , Dhakal Sudip , Basnet Prashant
Published: August 2022

Introduction: Oro-dispersible tablets are rapidly dissolved in saliva without the need for water and are beneficial for renal impaired, bedridden and psychiatric patients.
Objective: The study aimed to formulate oro-dispersible tablets of indomethacin with reduced adverse effects, better patient compliance, faster action, and convenience for patients.
Methods: Oro-dispersible tablets of indomethacin were prepared using three different super disintegrants; crospovidone, croscarmellose sodium and sodium starch glycolate with three different concentrations (2.5%, 5.2%, and 7.7%) by direct compression method. The prepared tablets were evaluated for pre and post-compression parameters including bulk density, tapped density, compressibility index, angle of repose, Hausner's ratio, hardness, friability, wetting time, in vitro disintegration time, and in vitro drug release.
Results: The percentage of drug released in 5 minutes of all formulations of Oro-dispersible tablets of Indomethacin was found to be 74.36% to 80.16% and the percentage of drug released in 10 minutes was 96.18% to 100%. All formulations showed disintegration time in the range of 19-78 seconds. The tablets prepared with 7.7% crospovidone (F6) shows faster disintegration (19 seconds) as compared to tablets prepared with sodium starch glycolate and croscarmellose sodium. The in-vitro dissolution studies showed that tablets of formulations batch containing 7.7% crospovidone releases 100% of the drug after 10 minutes which was fast released as compared to sodium starch glycolate and croscarmellose sodium.
Conclusions: Oro-dispersible tablets of indomethacin prepared with crospovidone showed better disintegration time and dissolution profile as compared to other superdisintegrants.
Anti-depressant Activity of the Seeds of Zanthoxylum armatum on Swiss Albino Mice
Authors: Yadav Chandrajeet Kumar , Poudel Kamal , Shrivastava Amit , Mehta Roshan , Yadav Tapeshwar
Published: August 2022

Introduction: Depression disorder has significant potential morbidity and mortality, contributing to suicide, incidence and adverse outcomes of medical illness, disruption in interpersonal relationships, substance abuse, and lost work time.
Objectives: The present study was designed to study the anti-depressant activity of the seeds extract of Zanthoxylum armatum using a forced swim test and tail suspension test on Swiss albino mice. The anti-depressant activity of the seeds of Zanthoxylum armatum was assessed using Chronic Unpredictable Mild-Stress (CUMS) induced depression in mice.
Methods: The animals were treated with the methanolic extract of seeds of Zanthoxylum armatum orally at two doses of 100, 200mg/kg body weight for eight days after CUMS induced depression in mice. The results demonstrate that Methanolic extract of seeds of Zanthoxylum armatum has got anti-depressant potential.
Results: The study showed that the extract of Zanthoxylum armatum had significant antidepressant activity. Microsoft Excel was used to calculate the mean ± SEM and one-way ANOVA followed by a turkey multiple comparison test was used to analyze the results. The seed extract presented significant antidepressant activity in mice (p<0.05).
Conclusions: This study was conducted to explore the antidepressant activity of seeds extracts of plant Zanthoxylum armatum in CUMS induced mice.
Covid-19 and its impact on Indian Foreign Policy: A Study
Authors: Patel Jignesh
Published: August 2022

The pandemic has been the most devastating event for the world since the Second World War. The pandemic as well as several geopolitical issues has made an already complex world even more complex. Its imbalance in the international system has increased. The second reality is that multipolarity is more relevant today than it was before. The pandemic has brought to the fore the importance of bringing diversity and resilience to supply chains, as well as the economic consequences of geopolitics and the risks associated with efforts to centralize power. India has always followed the ancient philosophy of Vasudhaiva Kutumbakam. Today there is an open society and democratic sentiments and cognizance of our responsibilities on the world stage. During the pandemic, India increased its drug production capacity to meet the demands, especially of paracetamol and hydroxychloroquine. Provided medicines to more than 150 countries, of which more than half were free or non-commercial. We have deployed our medical teams in the neighboring 4 countries. This sends a message to the whole world that India has the ability to not only help itself but to build good international relations. Prime Minister Modi has given a call for self-reliant India, which is important for the world. But after the second wave of Covid-19, foreign aid has also had to be accepted. The dire consequences of the pandemic have raised questions about regional primacy and leadership, which will have implications for the health of India's foreign policy in the years to come.
Contribution of Sardar Patel in the making of India and the relevance of his ideas
Authors: Chitranjan Kumar
Published: August 2022

Sardar Vallabhbhai Patel's service to the country, social service as well as patriotism and his determination, self-confidence, determination power, unshakable power, firm faith and devotion to work, he is known as 'Iron Man'. Is. Born on 31 October 1875 in Kheda, Gujarat, Sardar Vallabhbhai Patel was from a simple farmer family. Since childhood, his specialty of hard work and fearlessness, he passed the law examination in 1910 with first class, for which he also got a prize of Rs 750. Sardar Patel came into active politics of the country from 1917. In protest against the Jallianwala-Bagh massacre (1919), he went to Bardoli, influenced by the Satyagraha movement of Mahatma Gandhi and in 1920, where he spent his whole life in getting India's independence.
Education and ethics: reorienting values in Nigerian tertiary institutions
Authors: Maiyaki Joshua , Aliyu Jibril
Published: August 2022

Moral growth is a sign of human progress, and it must come before other elements of development in any country because otherwise, people' immorality would block the path of development. In a similar vein, a morally bankrupt education is incomplete, pointless, and detrimental to both the students who get it and the society in which they live. Therefore, the purpose of this essay is to critically analyse the place of ethics or morality in education. The research finds that moral probity is now lacking in our educational system via the use of historical and analytical methodologies. It then calls for reintroducing moral education to the teaching curricula of all higher institutions in Nigeria in order to reorient values in our tertiary institutions. According to the document, Nigeria should set the appropriate priorities by giving morality top priority in its educational and socioeconomic initiatives. Moral growth is a sign of human progress, and it must come before other elements of development in any country because otherwise, people' immorality would block the path of development. In a similar vein, a morally bankrupt education is incomplete, pointless, and detrimental to both the students who get it and the society in which they live. Therefore, the purpose of this essay is to critically analyse the place of ethics or morality in education. The research finds that moral probity is now lacking in our educational system via the use of historical and analytical methodologies. It then calls for reintroducing moral education to the teaching curricula of all higher institutions in Nigeria in order to reorient values in our tertiary institutions. According to the document, Nigeria should set the appropriate priorities by giving morality top priority in its educational and socioeconomic initiatives.
Presentación
Authors: Rodríguez Martínez María del Pilar , Caballero-Blanco Pablo
Published: August 2022

La motricidad humana ha tenido un papel fundamental en el desarrollo de los individuos y las sociedades a lo largo de la historia. Sus manifestaciones han sido diversas, desde la gimnasia, las luchas o las justas atléticas vinculadas a la preparación militar de la antigua Grecia y Roma hasta los juegos o actividades de carácter lúdico, relacionados con aspectos ceremoniales y rituales. La evolución de la motricidad humana y sus manifestaciones ha dado origen al desarrollo de campos disciplinares específicos, como la educación física, el deporte, la recreación, la actividad física o las prácticas motrices alternativas.
Thanks for joining our life: Intimacy as performativity on YouTube parenting vlogs
Authors: Vizcaíno-Verdú Arantxa , De-Casas-Moreno Patricia , Jaramillo-Dent Daniela
Published: August 2022

YouTube is currently becoming one of the main international platforms for amateur creators attempting to attract followers through a multiplicity of audiovisual content and engagement strategies based on search and algorithmic recommendation systems. In many cases, this environment, and especially its users, try to adapt to a celebrity network pattern on the basis of the construction of seemingly authentic and close relationships, leading to relevant phenomena such as parenting vlogs. This kind of content is focused on the presence of intimate moments that reflect the daily life of influencers or micro-influencers, capturing large numbers of followers, as well as important communication and information strategies. From this perspective, and through a quantitative content analysis of 1,034 videos and more than 900 viewing hours on two very popular YouTube family influencer channels, this study explores the degree of intimacy portrayed in their video content as performative strategies that configure the profiles’ post through interactions with followers, brands, and self-promotion. The results suggest that the degree of intimacy shown in this content becomes a performative process for these family youtubers, whereby the more intimate the exposure, the more popular the information offered to the user. In short, this type of content prioritizes the routines of the youtubers, who include their closest family members and friends as a means of attracting attention, while dedicating their time to interacting with brands (advertising) and recording, editing, and submitting a vast amount of personal and private information on the platform (dissemination) in a sort of promotional–private performativity.
Przestrzeń dźwiękowa Litzmannstadt Ghetto. Reportaże radiowe Joanny Sikorzanki.
Authors: Sygizman Kinga
Published: August 2022

Artykuł traktuje o reportażach dziennikarki Polskiego Radia Łódź, Joanny Sikorzanki, podejmujących tematykę Łodzi żydowskiej. Przemierzając współcześnie ulice, przy których mieszkali niegdyś Żydzi, eksplorując tereny, gdzie mieściło się getto, reportażystka stara się zbudować pomost pamięci między przeszłością i teraźniejszością, przywrócić znaczenie historycznej części miasta. Celem artykułu jest omówienie cyklu artykułów podejmujących tematykę Łodzi żydowskiej, ze szczególnym uwzględnieniem stylistyki przekazów, technik organizacji materii audialnej, budowania dramaturgii, a także sposobu pracy – rejestrowania nagrań czy rozmawiania z bohaterami. Podstawą teoretyczną dla rozważań o przestrzeni akustycznej współczesnej Łodzi stały się zagadnienia dotyczące pejzażu dźwiękowego. Analiza poetyki przekazów i analiza komparatystyczna pozwala wzbogacić interdyscyplinarne rozważania na temat pejzażu dźwiękowego miasta o wiedzę z zakresu teorii reportażu radiowego.   

Analizie i interpretacji poddane zostały cztery reportaże: tryptyk o śladach getta: „www.slady”, „ślady-reaktywacja” i „po śladach”, a także utwór „Czarni chytrzy”.
Pass-through in Colombia’s Unregulated Retail Electricity Market
Authors: Perez Alex , Carabali Jaime , Meneses Luis
Published: August 2022

This study analyzes the pass-through of wholesale costs to retail prices for unregulated users in the Colombian electricity market, using monthly data from 2012 to 2019. This period encompasses moments with and without an El Niño phenomenon. We use an empirical model to analyze the pass-through heterogeneity according to the characteristics of users and firms, showing that the pass-through is incomplete, differs according to the presence of El Niño, and is heterogeneous. The pass-through was greater from September 2015 to May 2016 because an El Niño caused hydrological resource scarcity and several critical thermal plants halted operations. In other words, the pass-through tends to be more comprehensive during an El Niño event. Additionally, the pass-through differs between firms with a high concentration of the market and the remaining firms and between urban and non-urban users.
Relaps/Refrakter Hodgkin Lenfoma Hastalarının Otolog Hematopoetik Kök Hücre Nakil Sonuçları ve Risk Faktörü Etkilerinin Retrospektif Değerlendirilmesi
Authors: ELGUN Ezel , GÜRSOY Vildan , ERSAL Tuba , PINAR İbrahim Ethem , ÖZKALEMKAŞ Fahir , OZKOCAMAN Vildan
Published: August 2022

Otolog hematopoetik kök hücre nakli (OHKHN) relaps/refrakter Hodgkin lenfoma (HL) için kurtarma tedavisi sonrasında uygulanılan standart bir tedavidir. Çalışma ile merkezimizdeki relaps/refrakter HL tanılı OHKHN uygulanılan hastaların hastalıksız (DFS) ve genel sağkalım (OS) saptamasını ve risk faktörlerinin sağkalım üzerindeki etkisini incelenmeyi amaçladık. Merkezimizde Ocak 2009–Mart 2020 tarihleri arasında takipli OHKHN uygulanılan 314 hastanın 35 (%11)’i HL tanılıydı. Çalışmaya relaps/refrakter HL tanılı 18 yaşından büyük OHKHN uygulanılan 35 hasta dahil edildi. Hastaların %46’sı kadındı. Medyan tanı yaşı 29 (14-62) ve nakil yaşı 33 (22-62)’idi. Primer kemoterapi sonrasında hastaların %66’sında remisyon sağlanırken %34’ü refrakter kaldı. Relaps/refrakter HL’ye uygulanılan kurtarma tedavisi sonucunda %6 parsiyel yanıt, %26 tam yanıt, %68 refrakter kabul edildi. OHKHN sonrası hastaların %49’unda remisyon sağlanırken, %51’inde relaps gelişti. OHKHN sonrasında relaps olan hastaların tedavi yanıtında %39’u remisyon, %17’si refrakter, %44’ü hayatını kaybetti. Hayatını kaybeden hastaların %88'i lenfoma kaynaklı, %12’si lenfoma harici nedenden kaybedildi. OHKHN sonrası hastaların ortalama OS 99(±8,9) ay; DFS 60(±10,7) aydı. OHKHN sonrası relaps süresi 12 ay altında (p=0,033) ve relaps anındaki sedimentasyon düzeyinin normal olması (p=0,021) DFS için anlamlı; relaps anında LDH düzeyinin normal olması (p=0,022) OS için anlamlı olduğu saptandı. Çok değişkenli analizde OS üzerinde etkili prognostik risk faktörü saptanmadı. Diğer taraftan DFS üzerinde; hemoglobin düzeyinde bir birimlik artışın relaps riskini 1,67 kat arttırdığı, nötrofil engraftmanında bir birimlik artışın relaps riskini %30 ve relaps süresi 12 ay üzerinde olmasının relaps riskini %85 düzeyinde azalttığı saptandı. Çalışmamızda hastaların birkaç risk faktörünün OHKHN sağkalımı ve süresi üzerinde etkili olduğunu saptadık. Ancak daha anlamlı sonuçlar için çalışmaların örneklem grubunun genişletilmesi ve takip süresinin uzatılması gerekmektedir.
A contribuição da psicologia do desenvolvimento no processo de ensino e aprendizagem
Authors: Gama Uberto Afonso Albuquerque da
Published: August 2022

A ação pedagógica é essencial na busca da fundamentação teórica e do conhecimento prático do saber e precisa ser uma realização permanente no trabalho do educador, para que este possa redimensionar a sua atuação no intento de melhorar o processo de ensino-aprendizagem, contribuindo para o desenvolvimento do ser humano. Nessa perspectiva, este artigo pautou-se na questão norteadora: quais pressupostos teóricos sobre a Psicologia do Desenvolvimento aplicada ao processo de ensino e aprendizagem estão vigentes na literatura? Com isso, teve-se como objetivo apresentar uma abordagem introdutória e sintética dos pressupostos teóricos vigentes na Psicologia Desenvolvimento quanto ao processo de ensino e aprendizagem. Sendo assim, este artigo utilizou como metodologia a pesquisa bibliográfica, por meio da qual observou-se que, tendo em vista o apoio que tem sido dado à visão sistêmica, enriquecida pela dialética, tem-se, atualmente, a oportunidade de buscar por uma estrutura unificadora das perspectivas teóricas fragmentadas desde as origens da Psicologia do Desenvolvimento, a fim de contribuir com a sociedade, edificando cidadãos presentes, espiritualizados e éticos.
Diet of the bonnethead (Sphyrna tiburo) along the northern Gulf of Mexico and southeastern Atlantic coast of the United States
Authors: Branham C. C. , Frazier B. S. , Strange J. B. , Galloway A. S. , Adams D. H. , Drymon J. M. , Grubbs R. D. , Portnoy D. S. , Wells R. J. D. , Sancho G.
Published: August 2022

The diet of a potentially omnivorous coastal shark species, the bonnethead (Sphyrna tiburo), was examined in the western Atlantic along the coast of the southeastern United States. A total of 423 stomachs collected from Texas, Alabama, Florida and South Carolina were analyzed using standardized stomach content analysis methods. The diet was dominated by crabs, primarily portunids (Callinectes spp.), across the geographical range analyzed, though the relative importance of crabs varied between regions. Ontogenetic shifts in diet were not observed throughout the region studied. Female and male bonnetheads in South Carolina displayed different diets, particularly in the amount of portunid crabs consumed, with a higher proportion ingested by females. Bonnetheads consumed limited amounts of seagrasses in all regions except in South Carolina, where they occupy habitats without seagrasses in marsh dominated bays and estuaries. This finding indicates that, at least seasonally, seagrasses are not an essential part of the diet of this shark species and may only occur in stomachs as accidental ingestion.
THE PRACTICE OF CRITICAL THINKING SKILLS IN TEACHING MATHEMATICS: TEACHERS’ PERCEPTION AND READINESS
Authors: Ismail Siti Noor , Muhammad Shamsuddin , Omar Mohd Norakmar , Shanmugam Kanageswari Suppiah
Published: August 2022

Purpose - This study was conducted to identify the relationship and influence of mathematics teachers’ perception and readiness on the practice of critical thinking skills (CTS) in implementing pedagogical processes in secondary schools. Methodology - Participants of the study consisted of 226 mathematics teachers who taught in three different secondary school categories, namely high performing schools (HPS), moderate performing schools (MPS) and low performing schools (LPS) throughout the state of Kelantan, Malaysia. The instrument used was adapted from Thurman (2009) to test the teachers’ perception of CTS, while the teachers’ readiness to apply CTS was adapted from Nagappan (2001) and Yusof and Ibrahim (2012). Besides, measurement of the teachers’ practice of CTS was adapted from Aldegether (2009), Barak and Shakhman (2008), and Shim and Walczak (2012). Findings - Teachers’ perception, readiness, and CTS practice in mathematics teaching were high in HPS but low in LPS. There was a strong positive relationship between teachers’ perception of CTS practice and teachers’ readiness to implement CTS practice in mathematics teaching. In addition, a total of 65 percent variance was contributed by both variables, namely teachers’ perception and teachers’ readiness for CTS practice in mathematics teaching, and this contribution was very high. Significance - The findings of the study also proved that the practice of CTS has improved the pedagogical quality of teachers, especially in meeting the needs of 21st century learning in the classroom. The emphasis on higher order thinking skills (HOTS) is a continuation of the excellence of teaching strategies through a variety of planned learning resources.
THE INTERACTION BETWEEN TEACHING COMPETENCIES AND SELF-EFFICACY IN FOSTERING ENGAGEMENT AMONGST DISTANCE LEARNERS: A PATH ANALYSIS APPROACH
Authors: Baba Rahim Norizan
Published: August 2022

Purpose - Distance learners are expected to actively participate in online learning settings to improve their cognitive level and promote more meaningful learning. However, without specific teaching skills and competencies from the instructors together with belief and capability of the distance learners themselves, their engagement in online learning would not be achieved. Limited studies have examined the extent of self-efficacy in encouraging student engagement in learning, especially within online learning settings. Thus, this study examined self-efficacy as a moderator to test its influence on the relationship between online teaching competencies and student engagement. Methodology - This quantitative research was conducted using the purposive sampling technique. This study involved 321 distance learners from a Malaysian public university. The questionnaire was created using SurveyMonkey, and the measurement items were adopted from past research with acceptable reliability. This study utilised partial least squares (PLS) 3.0 to test the hypothesis via correlation and path analysis. Findings - Contrary to expectations, the findings contributed to the literature that online teaching competencies and self-efficacy were not significantly related to student engagement. The association between online teaching competencies and student engagement was shown to be moderated by self-efficacy. This finding is aligned with Bandura’s (2001) social cognitive theory which states that personal factors such as self-regulation, self-efficacy, and interest are impacted in the distance education context. Significance - The results of this study can benefit online course instructors in Malaysian distance educational institutions to develop courses that enhance online learners’ self-efficacy. Online teaching competencies employed by online distance learners can be the primary objective when developing faculty development programmes that aim to coach online instructors to be competent in online teaching. Moreover, institutions are encouraged to introduce other online learning platforms to facilitate training of its practitioners in order to accelerate successful online teaching and learning experiences.
MATHEMATICS TEACHERS’ ONLINE TEACHING EXPERIENCE IN TIMES OF SCHOOL CLOSURES: THE CASE OF MALAYSIA
Authors: Jiew Fui Fong , Chin Kin Eng
Published: August 2022

Purpose – Given that students were out of school in response to the COVID-19 pandemic public health measures, traditional teaching practices have been forced to switch to online mediated learning environments. This study represents the first research effort to capture the experience of Malaysian mathematics teachers about their teaching during the pandemic. This includes investigating digital education tools mathematics teachers used, issues they encountered, and the knowledge and skills they need to improve during the enforced online teaching situation. Methodology – This study employed a survey design and qualitative data were collected using an online questionnaire. A total of 202 primary and secondary mathematics teachers from Malaysia participated in the study. The data were analysed through thematic analysis and descriptive statistics. Findings – First, it was found that the mathematics teachers employed a variety of digital education tools during the pandemic and the most commonly used tool was WhatsApp. Second, the top two issues faced by the teacher respondents were due to internet problems and students’ engagement during the online learning. A particular striking finding revealed that three-fifths of the teacher respondents who were concerned about the issue of students’ engagement were secondary mathematics teachers. Third, findings of the study further clarified that most of the teacher respondents wanted to improve their technological skills. Significance – This study supports mathematics teachers in making informed decisions about their teaching during school closures. The findings of this study also serve to alert the education sector about the issues related to the implementation of online education in times of the pandemic. In general, this study necessitates in developing preparedness for future pandemics.
THE EFFECT OF A GENRE-BASED PEDAGOGICAL APPROACH ON ORANG ASLI STUDENTS’ EFL WRITING PERFORMANCE
Authors: Ganapathy Malini , Kaur Manjet , Jamal Marlina , Phan Jonathan
Published: August 2022

Purpose – In the 21st century, the importance of having good English proficiency in Malaysia and globally has impacted educators, especially in terms of their pedagogical practices. Although students are exposed to 11 years of English language instruction in Malaysia, Orang Asli students still possess low English proficiency and poor writing skills. This study aims to determine the extent to which the genre-based pedagogical approach is able to improve Orang Asli students’ English as a foreign language (EFL) writing performance and analyse their responses in using the genre-based pedagogical approach as a framework to improve their EFL writing performance. Methodology – This quasi-experimental study included 78 students from a secondary school in Pahang, Malaysia. Participants were assigned to the experimental and control groups (N=39) to generate students’ pretest and posttest scores. Quantitative data from the students’ questionnaire were also triangulated with qualitative data from the focus group discussions with the experimental group.  Findings – The approach was effective in improving students’ descriptive writing and had a more significant effect than the mainstream process-based approach. Students reacted positively to the approach as they found it useful in improving their writing skills, which correlated with their improved test scores. Therefore, the genre-based pedagogical framework can be further enhanced by incorporating more grammar-related activities to meet the learning needs of Orang Asli students lacking in EFL writing skills. Significance – The novelty of this study is that the framework has the potential to be implemented in Malaysian secondary schools and other indigenous’ educational contexts. Furthermore, this study can be a point of reference to stakeholders, English language teaching (ELT) practitioners and educators in terms of advocating a genre-based pedagogical approach in an EFL context.
CREATING MEANINGFUL LEARNING EXPERIENCES WITH ACTIVE, FUN, AND TECHNOLOGY ELEMENTS IN THE PROBLEM-BASED LEARNING APPROACH AND ITS IMPLICATIONS
Authors: Mohamad Hsbollah Hafizah , Hassan Haslinda
Published: August 2022

Purpose – Previous studies have documented the positive effect of problem-based learning (PBL) on learners, especially in the medical discipline. However, such effect on learners in a specific course of Systems Analysis and Design (SAD) and how the PBL implementation in this course could contribute to meaningful learning are still under-researched. Therefore, this study aims to investigate how a PBL approach could be used in creating meaningful learning among the students of SAD and its effect on their skills. The focus is on how meaningful learning could be achieved through the integration of active learning with fun activities along with the use of technology (Active Fun Technology (AFT) elements) to nurture the students’ knowledge and enhance their soft skills. Methodology – The qualitative approach was adopted as a means to understand how PBL integrated with AFT elements could create meaningful learning experiences and its impacts on skills development. 108 self-reflections were received from the students. A thematic analysis was used to analyse data from the students’ self-reflection. Findings – Meaningful learning criteria and AFT elements were embedded during the process to create meaningful learning experiences. The finding of this study highlighted that PBL activities with the integration of AFT elements could be used to create meaningful learning. The study showed that the PBL implementation successfully created a meaningful learning experience and developed related skills during the learning process. In this regard, two major themes emerged from the thematic analysis, namely soft skills (social skills [with subthemes of friendship and sharing, accept others’ ideas], teamwork, communication, critical thinking, and problem-solving), and technical skills. Significance – The significance of the study was its suggestion of integrating AFT elements during the design and implementation of PBL activities. This is particularly important for educators who teach highly theoretical subjects and use PBL as their teaching approach and strategy to ensure engagement in stimulating students’ interests to learn the subject.
CHINESE STUDENTS’ METAPHORICAL DESCRIPTIONS OF THAI TEACHERS AT A THAI UNIVERSITY
Authors: Songsirisak Prommin , Jitpranee Jutharat , Lisec Albert , Boonjanawiroj Prasobkan , Wetpichetkosol Bhudtree , Kantamas Kannikar
Published: August 2022

Purpose – This paper discusses Chinese students’ negative and positive written feedback about Thai teachers using metaphorical descriptions and the links between it and their classroom experiences. Methodology – An open-response questionnaire was employed to collect the data from 21 Chinese female students. The questionnaire provided both positive and negative “people” or “thing” metaphors of Thai teachers for students’ selection. In addition, students were allowed to use their own metaphors to describe their teachers. Data was analyzed by using open and axial coding techniques. Findings – The results revealed that Chinese students were able to compare Thai teachers with either a “person” or “thing” metaphor and could write a metaphorical description that reflected different aspects of their instructors’ teaching, both positively and negatively. The quality of their descriptions was rich enough to link with their classroom learning experiences. Both positive and negative “people” and “thing” metaphorical descriptions were associated with three different viewpoints: academic, power dynamics, and emotion. The positive “people” metaphorical descriptions were linked to four classroom issues: knowledge and experience, teaching style, motivation, and guardian/protector. In contrast, the positive “thing” and negative “people” and “thing” metaphorical descriptions were linked to three classroom issues: knowledge and experience, teaching style, and emotion. Significance – These findings help to strengthen Thai-Sino understanding of the relationship between Chinese students and Thai teachers. Findings also suggested that Chinese students’ metaphorical feedback should be used with the non-metaphorical assessment form to evaluate and improve Thai teachers’ instructional practices in the Thai-Chinese student exchange curriculum.
SENIOR HIGH SCHOOL TEACHING: A PHENOMENOLOGICAL INQUIRY
Authors: Bacus Remedios Cabaral , Alda Rivika Coronado
Published: August 2022

Purpose - This study aims to explore the teachers’ lived experiences in Senior High School teaching.The K to 12 program is one curricular reform in the Philippines to ascertain that basic education graduates possess the required competencies at par with the international standards. Methodology - In this qualitative study, 15 Senior High School (SHS) teachers’ lived experiences were explored to arrive at the essence of SHS teaching at the onset of curriculum implementation. Using Husserlian phenomenological design and Colaizzi’s method of data analysis, three themes emerged from the in-depth interviews: expectations and apprehensions, experiences and strategies, and attitude and aspirations. The teachers have acknowledged their important roles and have remained optimistic despite the program’s limitations. Their unique experiences as they grapple with their new teaching assignment enthused them to explore ways to assist them in the teaching process. Findings - The findings provide academic institutions with input to revisit policies of SHS implementation by charting relevant trainings geared toward teachers’ professional development,  conducting regular onsite monitoring, and providing need-based support and resources for teachers’ up-skilling and re-skilling. Significance - With the requirements towards SHS implementation and the teachers’ collective aspirations, the Department of Education can continue to provide inclusive and equitable education for all.
Analysis of Personal Traits in 16 Omani English Language School Textbooks
Authors: Bataineh Adnan
Published: August 2022

This paper aims to analyze 16 English language school textbooks used in the Omani government schools. Quantitative and qualitative content analyses are used to investigate personality traits found in the textbooks. The analysis included all personal traits implied by images and texts in the textbooks. According to Hawkins’s (2007) classification of personal traits, personal traits are examined: traditional and feminist gender traits. The study results have indicated that there is a balanced representation of males and females in terms of personal traits. The study has also shown that the majority of masculine personal traits are stereotypical. Females were portrayed in different situations that conveyed masculine and feminine traits. Males were portrayed as risk-takers, self-reliant, nurturing, adventurous, decisive, competitive, and aggressive. Females were portrayed in a variety of personal traits such as nurturing, understanding, affectionate, risk-taker, self-reliant, competitive, aggressive, adventurous, and decisive.