bluuebunny/crossref_metadata_2025 huggingface dataset:
Importul de carne și organe comestibile al Republicii Moldova
Authors: Litvin Aurelia , Scerbacov Elena
Published: April 2024

The livestock of pigs has decreased significantly in farms specialized in raising pigs in the country, the cause being the coronavirus pandemic. Demand also fell for all pork products requested by both restaurants and picnics. Another cause that caused the reduction of the cattle herd was the increase in the price of fodder, as well as energy resources. Domestic meat production does not provide what is needed for processing factories. As a result, pork is imported because supplies are constant, the price is lower than for domestic production, and the quality is good. The Covid-19 pandemic caused an increase in meat processing expenses, as it was necessary to divide the workforce into shifts. The increase in expenses was also caused by the fact that hygiene products and special equipment were purchased for employees, but also for the repeated testing of employees. Imported meat is mostly frozen. This is stored for a long period of time to later be sold at high prices when there is a shortage of raw material on the domestic market. In 2021, compared to 2011, beef was imported more than 4 times, beef – 2,5 times, and poultry - 2 times. The Republic of Moldova imports meat from such countries as: Ukraine, Germany, Russia, Poland, Romania, Hungary. Unfortunately, domestic beef is exported, and Moldovans consume imported meat. Moldovans prefer to eat pork.
Rolul culturii floarea-soarelui în contextual problemelor economice curente existente în regiune
Authors: Osoianu Alexandru
Published: April 2024

The essential factor in enhancing the economic potential of a country lies in international trade and the exchange of goods with the global community. The magnitude of this potential is typically revealed through the export and import of goods, both of which exert economic and social impacts on the economy of the Republic of Moldova. This study aims to provide an analysis of a product with one of the most significant impacts on the volume of exports and imports in the Republic of Moldova and worldwide – sunflower. Currently, the sunflower seed market holds exceptional importance for farmers and intermediary traders, as a portion of their income is derived from the sale of sunflower seeds. Additionally, it is crucial for consumers who utilize sunflower oil and other products derived from this crop. This study presents a series of analyses related to the international and global trade of sunflower seeds, as well as the by-products obtained through seed processing.
Detection and Classification of Teacher-Rated Children's Activity Levels Using Millimeter-wave Radar and Machine Learning: A Pilot Study in a Real Primary School Environment
Authors: Wang Tianyi , Sakamoto Takuya , Oshima Y U , Iwata Itsuki , Kato Masaya , Kobayashi Haruto , Wakuta Manabu , Myowa Masako , Nishimura Tokomo , Senju Atsushi
Published: April 2024

Traditional assessments of children’s health and behavioral issues
primarily rely on subjective evaluation by adult raters, which imposes
major costs in time and human resource to the school system. This pilot
study investigates the utilization of millimeter-wave radar coupled with
machine learning for the objective and semi-automatic detection and
classification of children’s activity levels, defined as restlessness,
within a real classroom environment. Two objectives are pursued:
confirming the feasibility of restlessness detection using
millimeter-wave radar and proposing an algorithm for restlessness
classification through machine learning. The experiment involves a
nine-day observational study, using two radar systems to monitor the
activities of 14 children in a primary school. Radar data analysis
involves the extraction of distinctive features for restlessness
detection and classification. Results indicate the successful detection
of restlessness using millimeter-wave radar, demonstrating its potential
to capture nuanced body movements in a privacy-protected manner. Machine
learning models trained on radar data achieve a classification accuracy
of 100%, outperforming other methods in terms of non-invasiveness, lack
of body restraint, multi-target applications, and privacy protection.
The study’s contributions extend to children, parents, and educational
practitioners, emphasizing non-invasiveness, privacy protection, and
evidence-based support. Despite limitations such as a short monitoring
duration and a small sample size, this pilot study lays the foundation
for future research in non-invasive restlessness detection using
non-contact monitoring technologies. The integration of millimeter-wave
radar and machine learning offers a promising avenue for efficient and
ethical trait assessments in real-world educational environments,
contributing to the advancement of child psychology and education. This
work supports efforts for non-contact monitoring of children’s activity
holding promise such as non-invasive, privacy protection, multi-targets,
objective evaluation, and computer-aided screening.
An Appraisal of the Admissibility of Confessional Statement in a Trial Court in Nigeria
Authors: Emokpae Emokpae , Amadin Lugard , Abdulsalami Abdulsalami , Tijani Lucky
Published: April 2024

Confessional statements are important ingredience in criminal justice in Nigeria. A confession is an acknowledgment made by a person charged with a crime at any moment, admitting or implying that he committed that crime. Confessions are covered by sections 27 to 32 of the Evidence Act 1990 in Nigeria as well as section 28 to 31 of the Evidence Act of 2011. The specific goals are a critically examination of the circumstances under which confessional statements are admissible, to determine the effect of retracted confessional statements in criminal trials in Nigeria, as well as the circumstances under which confessional statements may be vitiated and to apply the findings in decided cases. To attain these goals, normative or doctrinal research is considered appreciate. This study found that where an inducement, threat, or promise was issued, any subsequent confessional statement obtained would be inadmissible. This study also reveal that a confession does not become inadmissible simply because the accused denies having made it; rather, the court must satisfy itself that the accused made the statement of his own free will and choice and without duress.
Uterine Rupture Factors and Neonatal Outcomes: Sudanese Cases
Authors: Ismail Haitham Abdallah Ali , Zakaria Ahmed Elnour Adam , Mohamed Nawal Ali Ahmed , Abdallah Abuelez Hassan Ibrahem , Bealy Mohamed Ahmed , Ahmed Hussain Gadelkarim
Published: April 2024

Background: Uterine rupture is linked to high rates of maternal mortality, especially in developing countries. Thus, this study aimed to evaluate the factors contributing to uterine rupture and the resulting neonatal outcomes in Sudan. Methodology: This study comprised of a series of 26 women presented with uterine rupture to the department of maternity at El-Obeid Teaching Hospital, El-Obeid, North Kordofan state, Sudan. The patients presented within one-year time. Results: In this particular group of patients, the neonatal population exhibited the following distribution: 19.2% (5 out of 26) were classified as Alive and well (WA), 23% (6 out of 26) required admission to the neonatal intensive care unit (NICU), 46.2% (12 out of 26) presented with Fresh Still Birth (FSB), and 11.6% (3 out of 26) displayed manifestations of Macerated Still Birth (MSB). Conclusion: Various factors can impact the outcomes of neonates following uterine rupture, such as the availability of facilities and demographic factors. The majority of newborns delivered showed unfavorable conditions.
Recuperação de Pacientes Queimados em Centro de Tratamentos De Queimados
Authors: Izél Amanda , Da Silva Aguiar Lucas , Ferreira de lima Natalia , Patrício Paes Rafaela , Batista Joicimara Sampaio , Da Silva Pereira Pabloena
Published: April 2024

INTRODUÇÃO: As queimaduras são lesões parciais ou totais da pele ocasionada por agentes químicos, térmicos, elétricos ou radioativos. É relevante ter o acompanhamento da equipe multidisciplinar especializada no atendimento e tratamento ao paciente queimado para reduzir o tempo de internação. OBJETIVO: Analisar bibliografias sobre a atuação do enfermeiro na recuperação de pacientes queimados. METODOLOGIA: Esse projeto trata-se de revisão de literatura, sobre o tema de recuperação de pacientes queimados em centros de tratamentos de queimados. As bases de dados utilizadas foram BVS, Literatura Latino-Americana e Caribe em Ciências da Saúde (LILACS) e Scientific Eletronic Library Online (SciELO), a partir dos descritores “queimaduras”, “lesão por queimadura”, “enfermagem”, “burns” e “nursing”. RESULTADOS: Após revisão da literatura, foram identificados diversos aspectos fundamentais relacionados ao papel da enfermagem na recuperação de pacientes queimados em centros de tratamento especializados. As principais áreas de foco incluíram o tratamento inicial, prevenção de infecções, manejo da dor, suporte psicossocial e educação para o autocuidado pós-alta. CONSIDERAÇÕES FINAIS: A recuperação de queimaduras pode ser um processo longo e desafiador. Os enfermeiros desempenham um papel importante em ajudar os pacientes a se adaptar e a desenvolver resiliência para enfrentar as mudanças em suas vidas
EFEKTIVITAS PROGRAM PENGELOLAAN BADAN USAHA MILIK DESA (BUMDES) DI DESA AYUNAN PAPAN KECAMATAN LOKPAIKAT KABUPATEN TAPIN
Authors: Sya'bani Arlan Agus
Published: April 2024

Desa merupakan pemerintah yang berada di tingkat bawah, namun memiliki peranan yang sangat penting dalam perubahan perbaikan ekonomi masyarakat. Ekonomi masyarakat yang lemah akan memberikan dampak negatif terhadap pembangunan nasional. Untuk menata perekonomian masyarakat desa secara baik dan benar Pemerintah Kabupaten Tapin membuat Program Pengelolaan Badan Usaha Milik Desa (BUMDes). Program ini bertujuan untuk meningkatkan kualitas ekonomi dan pemberdayaan masyarakat yang berfokus pada dampak perubahan ekonomi yang positif terhadap masyarakat. Desa Ayunan Papan merupakan salah satu dari 9 desa di Kecamatan Lokpaikat yang menggunakan Program Pengelolaan BUMDes serta dinobatkan sebagai desa terbaik nomor satu pelaksanaan Program Pengelolan BUMDes di Kabupaten Tapin. Metode penelitian ini yaitu deskriptif dengan pendekatan kuantitatif. Teori yang digunakan yaitu efektivitas program menurut Sutrisno (2007) terdiri dari 5 (lima) indikator antara lain: pemahaman program, tepat sasaran, tepat waktu, tercapainya tujuan, dan perubahan nyata. Teknik analisis data menurut Sugiyono (2013) yang terdiri dari 3 (tiga) tahap yaitu pengolahan, pengorganisasian, dan penemuan hasil.  Hasil penelitian ini menjelaskan bahwa pelaksanaan Program Pengelolaan Badan Usaha Milik Desa (BUMDes) di Desa Ayunan Papan Kecamatan Lokpaikat Kabupaten Tapin sudah  berjalan efektif. Nilai presentasi skor jawaban dari kuesioner Efektivitas Program Pengelolaan  Badan Usaha Milik Desa (BUMDes) di Desa Ayunan Papan Kecamatan Lokpaikat Kabupaten Tapin sebesar 77,13 % yang termasuk ke dalam kriteria efektif. Dapat dikatakan bahwa secara keselurahan pelaksanaan Program Pengelolaan Badan Usaha Milik Desa (BUMDes) di Desa Ayunan Papan Kecamatan Lokpaikat Kabupaten Tapin sudah berjalan secara efektif. Pada indikator pemahaman program nilai presentasi skor jawaban sebesar 77,45%, presentasi ini berada pada kelas interval 60,6%-80,5 % dengan kriteria efektif. Indikator tepat sasaran jumlah presentase sebanyak 82,88 % yang berada pada kelas interval 80,6%-100 % dengan kriteria sangat efektif. Indikator tepat waktu jumlah presentase sebanyak 82,60% yang berada pada kelas interval 80,6%-100% dengan kriteria sangat efektif. Indikator tercapainya tujuan jumlah presentase sebanyak 81,43% yang berada pada kelas interval 80,6%-100% dengan kriteria sangat efektif..Indikator perubahan nyata jumlah presentase sebanyak 81,40% yang berada pada kelas interval 80,6%-100% dengan kriteria sangat efektif.
MOTIVASI KEPALA MADRASAH DALAM MENINGKATKAN KINERJA PEGAWAI PADA MADRASAH TSANAWIYAH NEGERI 8 TABALONG KECAMATAN PUGAAN KABUPATEN TABALONG
Authors: Agustina Eka Santi , Ramadhani Syahril
Published: April 2024

Motivasi kepala madrasah merupakan faktor yang sangat penting dalam meningkatkan kinerja pegawai. Pada Madrasah Tsanawiyah Negeri 8 Tabalong kecamatan Pugaan Kabupaten Tabalong motivasi kepala madrasah belum sepenuhnya optimal. Kurangnya pengawasan dalam kedisiplinan waktu sehingga membuat kurang nya motivasi kinerja pegawai di madrasah terebut. Berdasarkan hal , penelitian ini bertujuan untuk mengetahui motivasi kepala madrasah dalam meningkatkan kinerja pegawai, faktor – faktor apa yang mendukung dan menghambat dalam meningkatkan kinerja pegawai, serta upaya apa yang dilakukan dalam meningkatkan kinerja pegawai pada MTsN 8 Tabalong Kecamatan Pugaan Kabupaten Tabalong.

Penelitian ini menggunakan pendekatan kualitatif dengan tipe penelitian deskriptif. Teknik pengumpulan data yang digunakan adalah wawancara, observasi dan dokumentasi. Sumber data melalui penarikan sampel yang berjumlah 8 orang. Setelah data terkumpul kemudian dianalisis teknik meliputi reduksi data, penyajian data, dan verifikasi atau penarikan kesimpulan.

Hasil dari penelitian menunjukan bahwa motivasi Kepala Madrasah dalam meningkatkan kinerja belum sepenuhnya optimal. Adapun faktor pendukung dan penghambat Kepala Madrasah dalam upaya meningkatkan kinerja pegawai diantaranya kurang disiplinnya waktu pegawai yang sering melanggarnya peraturan sehingga mengakibatkan rendahnya kinerja pegawai dan kurangnya sarana dan fasilitas di sekolah sehingga berpengaruh pada proses belajar mengajar kepada kecedasan anak didik MTsN 8 Tabalong. Dan upaya yang dilakukan oleh Kepala MTsN 8 Tabalong diantaranya meningkatkan kedisiplinan waktu dan pembelian sarana fasilitas yang kurang, agar dapat memotivasi para pegawai dalam bekerja.

Untuk meningkatkan kinerja pegawai, maka disarankan kepada Kepala Madrasah memberikan penghargaan kepada para pegawai yang dinilai paling berperan dalam hal meningkatkan kinerja pegawai. Adapun saran kepada seluruh pegawai dan staff agar bekerja dengan efektif dan efesien serta profesional dalam kedisiplinan waktu.
PEMANFAATAN INSTAGRAM SEBAGAI MEDIA PEMASARAN ONLINE PADA AKUN @NAJWAPROJECT
Authors: Latte Jumai , Artina Rusmini
Published: April 2024

Penelitian ini bertujuan Untuk mengetahui bagaimana pemanfaatan instagram sebagai media komunikasi pemasaraan online pada akun @najwaproject.

Bahwa sosial media menyediakan biaya informasi yang efektif dan efesien khususnya media instagram, hanya dengan waktu yang singkat dapat menyebarkan berbagai macam informasi maupun melakukan promosi, dan dengan memanfaatkan fitur-fitur isntagram yang ada pada instagram sangat memudahkan dalam penyebaran informasi dan sarana promosi.

Bahwa dengan memanfaatkan media instagram dapat meningkatkan pelayanan kepada pelanggan karena tersedia akses 24 jam, dan pelayanan pun bisa dilakukan di mana saja. Kata kunci : Instagram, Pemasaran Online
PROSPEK PRODUKSI LIVIA BAKERY DI DESA KERAMAT KECAMATAN AMUNTAI SELATAN KABUPATEN HULU SUNGAI UTARA
Authors: Agustina Eka Santi , Marliana Marliana
Published: April 2024

Dari hasil penelitian komponen-komponen teknologi yang merupakan kekuatan Livia Bakery adalah Technoware dan Humanware. Sedangkan kelemahannya  berada pada komponen Infoware dan Organware. Dari hasil analisis indikator  transformasi  perusahaan didapatkan  bahwa  perusahaan berada pada posisi yang sedikit dibawah rata-rata industri. Kemampuan teknologi yang dimiliki perusahaan saat ini adalah kemampuan operatif dan suportif, sedangkan kemampuan lainnya relatif lemah,terlebih pada kemampuan operatif yang dimiliki Livia Bakery adalah: (1) menggunakan peralatan dan prosedur yang dimiliki untuk memproduksi berbagai macam produk Bakery, (2) merencanakan produk apa saja yang akan dibuat secara rutin maupun tertentu, (3) mengatasi masalah mesin-mesin yang dimiliki.Saran penulis pada Livia Bakery, dalam rangka meningkatkan daya saing perusahaan ditingkat nasional maupun global, perlu dilakukan langkah-langkah strategis berikut: memperbaiki mutu, mengadaptasi dan menggunakan teknologi yang lebih maju, menggunakan skala ekonomi, memasuki pasar dengan nilai yang tinggi, menyesuaikan diri dalam hal penelitian dan pengembangan.
STRATEGI PEMASARAN UNTUK MENINGKATKAN PENJUALAN TAHU BASO DAN TAHU WALIK SI JACK DI KOTA AMUNTAI KABUPATEN HULU SUNGAI UTARA
Authors: Rifani Jamil , Azimah Safarina Harianty
Published: April 2024

Strategi pemasaran adalah alat fundamental yang direncanakan untuk mencapai perusahaan dengan mengembangkan keunggulan bersaing yang berkesenimbungan melalui pasar yang dimasuki dan program pemasaran yang digunakan untuk melayani pasar sasaran tersebut. Penelitian ini dilatarbelakangi oleh terkendalanya untuk memasarkan Tahu Baso dan Tahu Walik si Jack secara besar. Berdasarkan hal tersebut, penelitian ini bertujuan untuk mengetahui strategi pemasaran Tahu Baso dan Tahu Walik si Jack dan faktor yang mempengaruhi strategi pemasaran untuk meningkatkan penjualan Tahu Baso dan Tahu Walik si Jack di Kota Amuntai Kabupaten Hulu Sungai Utara. Penelitian ini menggunakan pendekatan kualitatif dengan tipe deskriptif kualitatif. Teknik pengumpulan data dengan cara wawancara, observasi, dan dokumentasi. Teknik penentuan informan dalam penelitian ini menggunakan teknik Maximum Variety Sampling sehingga terdapat informan berjumlah 10 orang. Hasil penelitian menunjukkan strategi pemasaran untuk meningkatkan penjualan Tahu Baso dan Tahu Walik si Jack di Kota Amuntai Kabupaten Hulu Sungai Utara dinilai sudah baik. Berdasarkan subvariabel kualitas pelayanan pada indikator merek dan jaminan berpengaruh dengan baik. Dimensi Harga yang mempunyai indikator kepastian harga dan keterjangkauan harga sudah baik. Dimensi Promosi pada indikator kreatifitas, inovasi dan daya tarik produk sudah terlaksana dengan baik. Faktor Yang Mempengaruhi Strategi Pemasaran untuk meningkatkan penjualan Tahu Baso dan Tahu Walik si Jack di Kota Amuntai Kabupaten Hulu Sungai Utara yaitu pertimbangan pembeli atau faktor pasar, faktor produksi atau pengawasan dan keuangan, serta Unsur Nilai Pemasaran Merek (brand).
PENGARUH KUALITAS PRODUK TERHADAP KEPUASAN KONSUMEN PADA KATERING SHOBIA DI KELURAHAN SUNGAI MALANG KECAMATAN AMUNTAI TENGAH
Authors: Hasanah Nurul , Fatmawati Fatmawati
Published: April 2024

Increasingly advanced technology and increasing activity at the present time make people prefer practical ways of fulfilling food and drinks for themselves, as well as for certain events. Plus the fast growing catering business in Indonesia, one of which is the catering business. Catering is always related to consumers, where customer satisfaction is one of the most important things for the continuity of catering. Consumer satisfaction is influenced by several factors, one of which is the quality of existing products. This study aims to determine the effect of product quality on customer satisfaction at Shobia Catering in Sungai Malang Village, Central Amuntai District.

The research method used is a quantitative research method. The population of this research is some consumers who buy products at Shobia Catering. Samples taken as many as 100 samples. While the data was collected using a questionnaire or questionnaire as the main method and dokumentation as a complementary method. Data analysis techniques used instrument tests (validity and reliability tests), simple linear regression analysis, T-test, and the coefficient of determination (R2) using the SPSS Version 22 application.

The results showed that there was a significant influence between product quality variables on customer satisfaction at Shobia Catering. Because the results of the hypothesis can be seen that tcount (7.838) > ttable (1.664) and a significant value (0.000) < (0.05). In addition, it can also be seen that the Cronbach's Alpha value on the product quality variable is 0.638 > 0.60 and the Cronbach's Alpha value on the consumer satisfaction variable is 0.853 > 0.60 so it can be concluded that the two variables are declared reliable. The R2-test the product quality factor has an influence of 38.5% on consumer satisfaction, while the remaining 61.5% is influenced by other variables not included in this study
EXPLORING HOME-BASED LEARNING: PERSPECTIVES AND EXPERIENCES OF GRADESCHOOLERS IN A PRIVATE ELEMENTARY SCHOOL
Authors: Lodyvina G. Angeles
Published: April 2024

This qualitative study delved into the experiences of grade school students within a private elementary school setting during the period of home-based learning. Utilizing semi-structured and structured interview techniques, twelve participants were engaged to gather rich insights into their encounters. Thematic analysis served as the primary method for data interpretation. The research revealed that modular learning presented considerable hurdles for students.
The shift to home-based learning appeared to diminish opportunities for socialization and peer interaction, given the limitations on direct engagement with teachers and classmates. Students encountered difficulties in managing time and maintaining focus without the direct supervision of teachers. Understanding modular learning materials proved to be challenging, particularly without timely clarification from educators. Moreover, restricted access to essential resources hindered students active engagement in the learning process.
This study sheds light on the implications of home-based learning in the context of private elementary schools. It emphasizes the urgent necessity for educational institutions and educators to address these challenges effectively, thereby enhancing the overall learning experience for students during periods of home-based education.
An Exploratory Study on the Standardization of Examination-Based and Course-Based Criteria for National Technical Qualifications
Authors:   Korean Society for the Study of Vocational Education, Oh Chun-Shik , Jung Dong Yul
Published: April 2024

This study aimed to unify examination criteria between test-based and process-based qualifications across 95 concurrent categories. Through a comparison of competency units, several key findings emerged: Test-based criteria generally included essential competencies of process-based qualifications, but with some differences. Practical exam criteria for test-based qualifications showed relatively high alignment with process-based essentials. Discrepancies varied by qualification grade, especially noticeable in technician levels. While sunset periods generally aligned, differences occurred in some categories. Policy recommendations are proposed based on these findings.
Calculation of Rayleigh Damping Coefficients for a Transient Structural Analysis
Authors: Grishin Andrey , Geraschenko Vitaliy
Published: April 2024

Direct numerical integration of differential equations of motion is widely used by engineers to describe the behavior of structures under dynamic loading. The method entails directly integrating the motion equations over time. In the direct method, the damping matrix is formed as a linear combination of mass and stiffness matrices multiplied by the Rayleigh damping coefficients α and β, respectively. The Rayleigh damping coefficients have a significant effect on the response of building structures under dynamic loading. Therefore, the design values of the damping coefficients α and β have crucial importance to ensure accurate and reliable results in a dynamic analysis. The paper presents a time domain analysis for a building subjected to seismic excitations using the modal superposition and direct integration methods. The direct method considers the damping properties of building structures by Rayleigh damping coefficients obtained using various approaches. The building's response to seismic load is compared by response spectra. The authors proposed the least conservative approach for calculating the Rayleigh damping coefficients for analyzing a building in the time domain.
Combination treatment of inflammatory bowel disease: Present status and future perspectives
Authors: Triantafillidis John K , Zografos Constantinos G , Konstadoulakis Manousos M , Papalois Apostolos E
Published: April 2024

The treatment of patients with inflammatory bowel disease (IBD), especially those with severe or refractory disease, represents an important challenge for the clinical gastroenterologist. It seems to be no exaggeration to say that in these patients, not only the scientific background of the gastroenterologist is tested, but also the abundance of “gifts” that he should possess (insight, intuition, determination, ability to take initiative, etc. ) for the successful outcome of the treatment. In daily clinical practice, depending on the severity of the attack, IBD is treated with one or a combination of two or more pharmaceutical agents. These combinations include not only the first-line drugs (e.g ., mesalazine, corticosteroids, antibiotics, etc ) but also second- and third-line drugs (immunosuppressants and biologic agents). It is a fact that despite the significant therapeutic advances there is still a significant percentage of patients who do not satisfactorily respond to the treatment applied. Therefore, a part of these patients are going to surgery. In recent years, several small-size clinical studies, reviews, and case reports have been published combining not only biological agents with other drugs (e.g., immunosuppressants or corticosteroids) but also the combination of two biological agents simultaneously, especially in severe cases. In our opinion, it is at least a strange (and largely unexplained) fact that we often use combinations of drugs in a given patient although studies comparing the simultaneous administration of two or more drugs with monotherapy are very few. As mentioned above, there is a timid tendency in the literature to combine two biological agents in severe cases unresponsive to the applied treatment or patients with severe extraintestinal manifestations. The appropriate dosage, the duration of the administration, the suitable timing for checking the clinical and laboratory outcome, as well as the treatment side-effects, should be the subject of intense clinical research shortly. In this editorial, we attempt to summarize the existing data regarding the already applied combination therapies and to humbly formulate thoughts and suggestions for the future application of the combination treatment of biological agents in a well-defined category of patients. We suggest that the application of biomarkers and artificial intelligence could help in establishing new forms of treatment using the available modern drugs in patients with IBD resistant to treatment.
OSW-1 triggers necroptosis in colorectal cancer cells through the RIPK1/RIPK3/MLKL signaling pathway facilitated by the RIPK1-p62/SQSTM1 complex
Authors: Wang Nan , Li Chao-Yang , Yao Teng-Fei , Kang Xiao-Dan , Guo Hui-Shu
Published: April 2024

BACKGROUND

Necroptosis has emerged as a novel molecular pathway that can be targeted by chemotherapy agents in the treatment of cancer. OSW-1, which is derived from the bulbs of Ornithogalum saundersiae Baker, exerts a wide range of pharmacological effects.

AIM

To explore whether OSW-1 can induce necroptosis in colorectal cancer (CRC) cells, thereby expanding its range of clinical applications.

METHODS

We performed a sequence of functional experiments, including Cell Counting Kit-8 assays and flow cytometry analysis, to assess the inhibitory effect of OSW-1 on CRC cells. We utilized quantitative proteomics, employing tandem mass tag labeling combined with liquid chromatography-tandem mass spectrometry, to analyze changes in protein expression. Subsequent bioinformatic analysis was conducted to elucidate the biological processes associated with the identified proteins. Transmission electron microscopy (TEM) and immunofluorescence studies were also performed to examine the effects of OSW-1 on necroptosis. Finally, western blotting, siRNA experiments, and immunoprecipitation were employed to evaluate protein interactions within CRC cells.

RESULTS

The results revealed that OSW-1 exerted a strong inhibitory effect on CRC cells, and this effect was accompanied by a necroptosis-like morphology that was observable via TEM. OSW-1 was shown to trigger necroptosis via activation of the RIPK1/RIPK3/MLKL pathway. Furthermore, the accumulation of p62/SQSTM1 was shown to mediate OSW-1-induced necroptosis through its interaction with RIPK1.

CONCLUSION

We propose that OSW-1 can induce necroptosis through the RIPK1/RIPK3/MLKL signaling pathway, and that this effect is mediated by the RIPK1-p62/SQSTM1 complex, in CRC cells. These results provide a theoretical foundation for the use of OSW-1 in the clinical treatment of CRC.
THE IMPACT OF INTERNAL CORPORATE GOVERNANCE MECHANISMS ON RELEVANCE OF THE VALUE OF ACCOUNTING INFORMATION FOR IRAQI BANKS LISTED ON THE IRAQI STOCK EXCHANGE
Authors:   Al-Muthanna University, College of Administration and Economics, Departmentof Business Administration, Iraq, Ayyed Ali Lateef
Published: April 2024

The research aims to study the impact of the internal mechanisms of corporate governance on the appropriateness of the value of accounting information. To achieve the research goal, the price model was used to measure the appropriateness of accounting information's value. The research community was also represented by commercial banks listed on the Iraqi Stock Exchange, while the research sample was represented by (10) Commercial banks listed on the Iraq Stock Exchange. The study concluded that there is a statistically significant effect of the independent variable, the number of board of directors meetings, on the appropriateness of the value of accounting information in commercial banks. The number of independent members also has a statistically significant impact on the appropriateness of the value of accounting information.
Reviewing explore/exploit decision-making as a transdiagnostic target for psychosis, depression, and anxiety
Authors: Lloyd Alex , Roiser Jonathan P. , Skeen Sarah , Freeman Ze , Badalova Aygun , Agunbiade Adeola , Busakhwe Chuma , DeFlorio Carla , Marcu Anna , Pirie Heather , Saleh Romana , Snyder Theresa , Fearon Pasco , Viding Essi
Published: April 2024

In many everyday decisions, individuals choose between trialling something novel or something they know well. Deciding when to try a new option or stick with an option that is already known to you, known as the “explore/exploit” dilemma, is an important feature of cognition that characterises a range of decision-making contexts encountered by humans. Recent evidence has suggested preferences in explore/exploit biases are associated with psychopathology, although this has typically been examined within individual disorders. The current review examined whether explore/exploit decision-making represents a promising transdiagnostic target for psychosis, depression, and anxiety. A systematic search of academic databases was conducted, yielding a total of 29 studies. Studies examining psychosis were mostly consistent in showing that individuals with psychosis explored more compared with individuals without psychosis. The literature on anxiety and depression was more heterogenous; some studies found that anxiety and depression were associated with more exploration, whereas other studies demonstrated reduced exploration in anxiety and depression. However, examining a subset of studies that employed case-control methods, there was some evidence that both anxiety and depression also were associated with increased exploration. Due to the heterogeneity across the literature, we suggest that there is insufficient evidence to conclude whether explore/exploit decision-making is a transdiagnostic target for psychosis, depression, and anxiety. However, alongside our advisory groups of lived experience advisors, we suggest that this context of decision-making is a promising candidate that merits further investigation using well-powered, longitudinal designs. Such work also should examine whether biases in explore/exploit choices are amenable to intervention.
THEFT FROM "SOMEONE ELSE'S POCKET": QUALIFICATION PROBLEMS
Authors: Чернышев Дмитрий Борисович
Published: April 2024

Введение: в статье рассматривается проблема квалификации кражи имущества из одежды, сумки или другой ручной клади, находившихся при лице, не являющемся собственником похищенного, то есть не подлежащим признанию потерпевшим. Материалы и методы: материалами явились вступившие в силу решения судов, научные исследования. Методологическую основу исследования составили методы системного анализа российского уголовного законодательства, анализ судебной практики. Результаты исследования: в ходе исследования автором рассмотрена проблема квалификации тайного хищения имущества у лица, не обладающего по отношению к имуществу классической триадой полномочий, образующих право собственности. Установлена проблема невозможности формального признания его потерпевшим согласно существующей редакции п. «г» ч. 2 ст. 158 УК РФ, что препятствует квалификации в соответствии с фактическими обстоятельствами совершенного преступления. Обсуждение и заключение: автором предложено внести изменения в диспозицию п. «г» ч. 2 ст. 158 УК РФ, изложив ее в следующей редакции: «кража, то есть тайное хищение чужого имущества, совершенная из одежды, сумки или другой ручной клади, находящихся при собственнике или ином владельце».

Introduction: the article discusses the difficulties in determining the theft of property from personal belongings such as clothes, bags, or hand luggage that were not owned by the victim. Materials and Methods: the study was based on court decisions that had come into force, as well as scientific studies. The methodological basis of the study was the systematic analysis of Russian criminal legislation and analysis of judicial practice. Results: the author researched the issue of qualifying hidden theft of property from a person who does not possess the classical triad of powers that constitute the right of ownership. It was found that paragraph “d” of Part 2 of Article 158 of the Criminal Code of the Russian Federation poses a problem of impossibility in formal recognition as a victim, which precludes qualification in accordance with the actual circumstances of the crime committed. Discussion and Conclusions: the author proposes an amendment to the disposition of paragraph “d” of Part 2 of Article 158 of the Criminal Code of the Russian Federation. The proposed amendment defines theft as the hidden theft of someone else's property from clothes, bags, or other hand luggage located with the owner or another owner.
THE THREAT OF MURDER OR SEVERE HARM TO HEALTH: GOAL SETTING FEATURES
Authors: Векленко Сергей Владимирович , Шутова Юлия Александровна
Published: April 2024

Введение: статья посвящена исследованию цели совершения угрозы убийством или причинением тяжкого вреда здоровью. Материалы и методы: при написании статьи использовались результаты собственных эмпирических исследований. Применялись общенаучные и частнонаучные методы исследования, которые позволили проанализировать и обобщить собранные авторами относящиеся к предмету исследования материалы из различных источников. Обзор литературы: применялись труды отечественных ученых в области уголовного права, общей теории права, философии и психологии. Результаты исследования: авторами выявлена сущность цели-результата совершения угрозы убийством или причинением тяжкого вреда здоровью, использование которой отражает идею использования унифицированного понятийно-категориального аппарата в целях создания единообразной правоприменительной практики. Обсуждение и заключение: авторами сформулированы предложения, которые позволят правоприменителям единообразно понимать целеполагание при угрозе убийством или причинением тяжкого вреда здоровью. Обозначенные предложения направлены на повышение эффективности защиты личности от преступных посягательств на психическое и социальное здоровье.

Introduction: the article examines the threat of murder or severe harm to health. Materials and Methods: the authors conducted their own empirical study and used universal and special research methods to analyze and summarize materials from various sources. Literature Review: includes works by Russian criminal law, general theory of law, psychology, and philosophy scientists. Results: the authors have identified the essence of the 'goal-result' of the threat of murder or severe harm to health. Its usage reflects the idea of using a unified conceptual and categorical apparatus to create uniform law enforcement practices. Discussion and Conclusions: the authors provide suggestions to help enforcers understand the goal setting unambiguously concerning threatening to kill or cause serious harm to health.
THE INTERMEDIATE COURT OF APPEAL IN THE FORM OF JUDICIAL CONTROL IN THE RUSSIAN CRIMINAL PROCEEDINGS: GENESIS OF THE PROBLEM
Authors: Ибрагимова Алиса Мансуровна
Published: April 2024

Введение: в статье раскрывается проблема межотраслевой конкуренции норм уголовно-процессуального законодательства и законодательства об административном судопроизводстве, посвященных обжалованию действий (бездействия) и решений участников уголовного судопроизводства, наделенных уголовно-процессуальными полномочиями, в порядке судебного контроля. Материалы и методы: эмпирическую базу исследования составили материалы прокурорско-следственной и судебной практики. Методологическую основу исследования составили общенаучный метод диалектики, а также такие частнонаучные методы познания, как системный, сравнительно-правовой, формально-юридический методы познания, индукция и дедукция. Результаты исследования: проведенное автором исследование позволило выявить противоречия в правовом регулировании между нормами уголовно-процессуального права и нормами об административном судопроизводстве, обосновать и предложить изменения в действующее законодательство, сформулировать понятие межотраслевого правового института обжалования в форме судебного контроля в уголовном судопроизводстве. Обсуждение и заключение: автором приводится теоретическое обоснование способов решения проблемы межотраслевых противоречий в рамках исследуемого института, а также предлагается внесение изменений в действующее законодательство, излагается авторская редакция некоторых положений статьи 1 Кодекса административного судопроизводства Российской Федерации.

Introduction: the article examines the issue of intersectoral competition between criminal procedural law and administrative procedural law. In particular, it focuses on the challenge to acts (or omissions) and decisions of participants in criminal proceedings who have criminal procedural powers, and the challenges that arise in the context of judicial review. Materials and Methods: the empirical basis of the study consists of prosecution and investigation materials as well as court records. The study was based on the universal scientific research method of dialectics, as well as specific research methods of cognition, including systemic, comparative and legal cognition, and the legal method of cognition, as well as induction and deduction. Results: the results revealed contradictions in the legal regulation between the norms of criminal procedure and the Administrative Procedure Act. The author has justified and proposed changes in the current law. The author defined the concept of an interbranch legal institution of appeal by way of judicial review in criminal proceedings. Discussion and Conclusions: the author provides a theoretical justification for addressing intersectoral contradictions within the studied institution. In addition, the author proposes amendments to the current legislation and outlines their version of certain provisions of Article 1 of the Code of Administrative Procedure of the Russian Federation.
How Do Instagram Messages Affect the Use of Renewable Energy? -- Applica-tion of an Extended Information Adoption Model
Authors:   Advancing System Analysis, International Institute for Applied Systems Analysis, Laxenburg, A-2361, Austria, Komendantova N. , Zobeidi T. ,   Advancing System Analysis, International Institute for Applied Systems Analysis, Laxenburg, A-2361, Austria, Yazdanpanah M. ,   Advancing System Analysis, International Institute for Applied Systems Analysis, Laxenburg, A-2361, Austria,   Agricultural Sciences and Natural Resources, University of Khuzestan, Khuzestan, Mollasani, 6341773637, Iran
Published: April 2024

As social media can play an important role in creating awareness of the need to mitigate climate change and of the benefits of renewable energy (RE), we examined the influences of social media on attitudes to renewable energy, including intention to use it. This study is novel in two ways: it simultaneously considers message characteristics and message-receiver perceptions as factors influencing the acceptance of renewable energy; and it is also the first study to use an extended information adoption model to evaluate the impact of Instagram on information adoption and the intention to use renewable energy sources. Our questionnaire, based on the theory of information adoption, included items on attitude toward information and trust in Instagram, and was randomly distributed online among followers of renewable energy pages on Instagram. A total of 173 people completed the questionnaire. Structural equation modeling showed that quality of argument had a positive and direct effect on the perceived usefulness of information. Source credibility as a peripheral path also indirectly increased perceived usefulness by changing attitude toward information. Moreover, perceived usefulness had a direct impact on information adoption and increased information adoption through trust of the materials.
Pdf to Voice by Using Deep Learning
Authors: Beevi S.Sarjun , Gopi Chand Tayi , Hemanth Reddy Tamatam , Rama Naga Sai Gokul Tammana , Harika Alamuru
Published: April 2024

Audio books are extraordinary for people who, like most people, want to listen to themselves read. These can't be bought and stored within the library at domestic. Audiobooks are a notable manner to rest your eyes and take a damage from the steady stimulation of virtual gadgets. Others as a time shop. For instance, hold studying books even as doing exceptional responsibilities on the equal time. Not only will this lessen the issues of millennials, but it's going to also be a valuable tool for lowering human being’s visibility. The ability to transform any content material into an audiobook is a true present of humanity. Our technology may be used to develop such gadgets. Text-to-speech and other recitation applications are extensively used to assist college students broaden studying comprehension abilities. The PDF to Audio System is a screen reader designed and developed for powerful audio verbal exchange. The International Organization for Standardization (ISO) has unique PDF documents as an open file format. Document layout is one of the handiest formats for digital conversation and facts change. This is very essential if we want to improve the accessibility of our readers' display screen by adding audio to our content material. Features from PDF files encompass hyperlinks and buttons, as well as audio and video documents. Multiple languages may be supported the use of PDF-to- audio generation, which lets in customers to hear text definitely (spoken).
Implantation of Android for Better Health with Medication Management App
Authors: Mahendiran N. , Ramya N
Published: April 2024

The Android application has been developed with the aim of assisting patients in maintaining their health by reminding them of their medication schedules through an Alarm Ringing system. Targeting individuals prone to forgetting their dosage timings, this application provides a user-friendly interface for setting alarms with fields for date, time, and medicine description. Users have the flexibility to schedule alarms for multiple medications at various intervals according to their prescribed regimen. Additionally, a notification system is integrated to alert users after configuring the alarm settings. Furthermore, users retain control over the activation and deactivation of these notifications as per their preference. This study presents a system leveraging the Android Operating System to facilitate medication adherence through timely reminders and automatic alarm functionalities. In today's fast-paced and stress-laden lifestyle, individuals are increasingly susceptible to various illnesses, underscoring the importance of maintaining health and wellness. With the ubiquitous presence of smartphones in our tech-driven society, these devices serve as indispensable tools. Leveraging this technology, the proposed system aims to harness the potential of smartphones to enhance health management practices. By incorporating notifications and automated alarms, the system seeks to alleviate the challenges associated with medication adherence, thereby contributing to improved overall well-being.
Implementing the Pedal-Craft Sawing Machine
Authors: Barai Sagar , Benibagde Nitin , Potekar Soham , Gajbhiye Rakesh
Published: April 2024

The purpose of this project is to design and build a pedal-powered hacksaw cutting machine. This project aims to offer a more contemporary and effective way to cut wood, metal, and plastic. It is highly beneficial to the lathering, furniture-making, and PVC material (pipe) cutting sectors. Because it uses a slider crank mechanism to transform the flywheel's rotational movement into the hacksaw's reciprocating motion while the user cycles, this tool can also be used as a fitness training machine while cutting. Following testing, the device showed a perfect mechanical advantage and overall good efficiency.
THE MODERATING EFFECTS OF STATUTORY LAWS AND REGULATIONS OF RISK FACTORS AND MANAGEMENT IN THE KINGDOM OF SAUDI ARABIA CONSTRUCTION INDUSTRIES
Authors: Rehman Muhammad Abdul , Ishak Md Sayuti Bin , Adeleke Adekunle Qudus
Published: April 2024

Purpose – Construction projects are fraught with hazards that have a detrimental impact on schedules, estimates, and quality. The project execution phase exposes contractors to internal and external hazards, either implicitly or explicitly. A project’s achievement is contingent on the proper handling of internal and external hazardous concerns. This study investigates the connection linking internal and external risk factors with risk management in Saudi Arabian contractors and the moderation role of government bylaws linking this connection.
Research methodology – This study investigates 303 Saudi Arabian contractors to explain the influence of internal hazards, external hazards, and governmental by-laws on risk management by applying the Partial Least Squares Structural Equation Modeling (PLS-SEM) method.
Findings – The outcome indicates that internal hazards (active leadership, team competency, and skills and effective communication), external hazards (technological, political, cultural, and economic factors), and government by-laws (also, its moderation role with external hazards) are positively connected with risk management resulting a moderate effect. Furthermore, the outcome also highlights that the moderating influence of government by-laws with internal risk factors is insignificant.
Research limitations – The current research model depicted 74.4% of the overall variation in risk management. Other latent variables can explain the 25.6% remaining overall variation in risk management which can be taken into account for future aspects of effective construction risk management.
Practical implications – This study raises the efficiency of Saudi Arabian contractors by improving project output delivery. This study made recommendations to boost risk management usage.
Originality/Value – This research was conducted for the first time in the Kingdom of Saudi Arabia, and it is an original work.