bluuebunny/crossref_metadata_2025 huggingface dataset:
FEATURE OF THE IMPACT OF THE ECONOMY’S DIGITIZATION ON THE EFFICIENCY OF TAX CONTROL
Authors:   Plekhanov Russian University of Economics, KRYLOVA Daria Eduardovna , AKHMADEEV Ravil Gabdullaevich ,   Plekhanov Russian University of Economics, MOROZOVA Tatiana Viktorovna ,   Plekhanov Russian University of Economics, ZVEREVA Anna Olegovna ,   The Russian Presidential Academy of National Economy and Public Administration
Published: April 2021

In public administration, the introduction of digital information technology is one of the priorities in the area of taxation development. Of particular importance is the transformation of the state system of tax management, as well as understanding the functional aspects of its development under Covid-19. Meanwhile, the current tendency in the part of reduction of economic activity by subjects of tax relations is conditioned by appearance of objective factors directly influencing the process of tax management, not only from the position of revenue part of state budget, but also development of systems of tax control. These aspects manifest themselves to a greater extent in the search for priority of fiscal component and underestimation of regulatory policy of state tax administration. In this regard, it is important to timely identify tax and levy arrears in the implementation of cameral tax measures. In addition, when implementing forms and methods of tax control at the modern level, both increasing the level of cybersecurity, protecting confidential data of taxpayers and the introduction of crowdsourcing elements through mobile information technologies are considered as potential solutions in the field of digital development of the domestic tax system. The study is based on the assessment of the forms and methods of tax control in the form of in-house tax audits as an opportunity to identify positive effects from the introduction of digital technologies by the Federal Tax Service of Russia in terms of tax audits in the form of DTA.
ACTIVATION OF TECHNOLOGIES FOR MARKETING SERVICES IN THE FINANCIAL SECTOR IN MODERN CONDITIONS
Authors:   Financial University under the Government of the Russian Federation, Sinyaeva Inga Mikhailovna
Published: April 2021

In this article, the author reveals the need to activate marketing technologies of market participation in practice in the context of the COVID-19 pandemic. The author quite fully reveals the specifics and content of financial sector services, highlighting current trends and patterns. At the same time, the theoretical contribution of domestic and foreign authors is noted. With the illustration of Figure 1, the author notes that due to COVID-19, many industries have sharply reduced traffic by 40 percent or more, but in the finance, health and nutrition sectors, on the contrary, there has been an increase in traffic from 10 to 30 percent. The scientific novelty lies in the author’s recommendations on the activation of marketing technologies for a comprehensive assessment of: market environment factors (EFAS-analysis model) and the competitive environment (the polygon of success factors and risks of a financial organization).
ON SUPERCONTINUOUS FUNCTIONS IN TOPOLOGY
Authors: Bhat Ramesh
Published: April 2021

The aim of this paper is to introduce and study new classes of continuous functions and its properties in topological spaces comparing with different types of continuous functions.
"Adults Control It Better." Health-related Practices, Responsibilities and Bonding in the Narratives of Polish Children
Authors: Maciejewska-Mroczek Ewa
Published: April 2021

This paper shows how everyday health-related practices are played out in respect to performing parent–children relationships. Based on research with children aged 8–11 years old, conducted in Poland in 2015–18 with the aim of studying their opinions about health, this paper shows that children frame health-related practices in a broader set of social networks. This paper suggests that negotiations concerning healthy lifestyle, common among modern families in Poland, represent rituals through which parent–child relationships are practiced. What is more, children play an active role in this process. Children feel responsible for their own and their family’s health and consider health-related practices as a way of “doing family”.
Developing Students' Creative Constructs in Mathematics with Problem-Based (PB) and Problem Posing (PP) Tasks
Authors: Roble Dennis B. , Lomibao Laila S. , Luna Charita A.
Published: April 2021

The purpose of this experimental study was to examine the creative constructs of students enrolled in Differential Calculus at the University of Science and Technology of Southern Philippines, Cagayan de Oro City, Philippines. This study was composed of 132 engineering and mathematics education students enrolled in two different semesters. The experimental group was chosen randomly, exposed to the problem-based HALP model teaching approach and problem posing while the control group was taught using Polya’s problem-solving heuristics. Multiple Solution Tasks (MST) test in Calculus was administered to determine their creative constructs which can be measured in terms of their level of mathematical fluency, flexibility and novelty of solutions before and after the experiment. Results indicated that the experimental group exhibited a remarkable improvement of their mathematical fluency and flexibility but still in the developing level when they are required to posit novel solutions to problems as influenced by the problem-based HALP and problem posing activities. Hence, it is recommended that mathematics teachers may utilize these methods to successfully develop students’ mathematical creativity and future research may also be explored on integrating technology and how it can influence developing student’s mathematical creativeness as well as the mediating role of their affective domains and IQ (intelligent quotient).
Lioness Dreaming: A Somatic Approach to the Animal Ally
Authors: Nelson Elizabeth Éowyn
Published: April 2021

The essay uses transpersonal and Jungian psychologies to describe a profound encounter with an aging lioness in the South African bush. It explains somatic dreaming as a practice of intentionally dwelling with exceptional experience by focusing on the bodily responses of the dreamer and the vivid somatic aspects of the dream images, or figures, as embodied others. The autonomous figures of what transpersonal psychology calls an exceptional human experience (EHE) and Jungians describe as a numinous waking vision (in contradistinction to a night time dream) are both deeply strange and strangely familiar. What are the possibilities and challenges of somatic dreaming while awake? How might such an approach evoke and express soul? The author contends that hosting living images in and with the body can be powerfully transformative, altering the course of one’s life.
Diversifikasi Produk Olahan Jamur Tiram untuk Menunjang Perekonomian Masyarakat di Kabupaten Jember
Authors: Wahyudi Muhammad Iwan , Tripama Bagus , Prayuginingsih Henik , Warisaji Taufik Timur
Published: April 2021

The Stimulus Community Partnership Program (SCPP) activities aims to support oyster mushroom farmers in Jember by improving skills and knowledge for diversifying oyster mushroom processing, building networks and markets, stimulating capital, and improving business managerial which are the main problems of partners in developing their businesses and economies. The SCPP activity method uses capacity building with a community driven development approach which is based on activities that are cognitive, affective, and psychomotor in the context of added value products and oyster mushroom business management including marketing to increase income and partner economy. The results of SCPP are in the form of improving partners' skills in processing oyster mushrooms into 5 prospective products that are needed by the market. In addition, increasing skills in business management starting from planning, organizing partne r members, evaluating product quality, simple bookkeeping, opening online/offline market access as well as strengthening capital in the procurement of production infrastructure are the next outputs of the service activities carried out. This program has been able to solve partner problems in improving the skills of diversifying oyster mushroom processing into processed products that have high prospects in the market. Improved business management and access to new markets, especially online, as well as injections of capital into fresh energy for partners and members to develop their businesses and economies.
Pemberdayaan KWT Ayu Tangkas pada Program Pengembangan Desa Mitra Mandiri Pangan
Authors: Ni Putu Sukanteri  , Suryana I Made , Verawati Yenny , Yuniti I Gusti Ayu Diah
Published: April 2021

Megati Village is located in East Selemadeg Subdistrict, Tabanan Districty. It has a strategic position, so that it can become a potential development for independent food partner villages based on local resources. The purpose of the activity is to foster and assist the group of women farmers (GWF) in the village of Megati towards the Self-Sufficient Food Group. Training and mentoring for home industry groups are carried out intensively in order to produce products that are ready to sell and have good quality. The Participatory Research Action (PAR) method is a participatory approach, carrying out all activities together with the target community. In addition, using a technology transfer approach, in order to provide new innovations in terms of appropriate technology in accordance with the needs of the target community. The results obtained in the service activities at GWF Ayu Tangkas carried out in Megati Village, East Selemadeg Subdistrict, Tabanan District have been running for 100% in processing agricultural products in the form of cassava into various processed cakes of economic value. Processing cassava into rolled sponge, steamed sponge, cake, donut, and various variants of local and national cakes. Training on management and administration of women groups includes the preparation of administrative documents in the form of a group activity book, an activity attendance book and a financial report book for GWF Ayu Tangkas.
Peningkatan Keterampilan bagi Pengelola dan Anggota Badan Usaha Milik Desa di Desa Amokuni, Kecamatan Ranomeeto Barat, Kabupaten Konawe Selatan, Sulawesi Tenggara
Authors: Mas’ud Arifuddin , Raharjo Sapto , Abdullah Weka Gusmiarty , Nurdin Emilia , Mustafa Santiadji
Published: April 2021

The objective of this community service activity are to increase knowledge and skills to managers and members of Amokuni Village Owned Enterprise (Bumdes Amokuni) regarding business management, added value, determining the cost of goods manufactured (HPP), and creative marketing strategies. Activities carried out include socialization, extention, training and mentoring. The result of this service activity was that the knowledge and skills of the managers and members of Bumdes Amokuni have increased. Increased knowledge was meant in terms of business management, increasing the added value of freshwater resources, HPP determining and creative marketing strategies for freshwater fish products to be produced. Improved skills were in the form of skills in making business management concepts, processing pomfret and tilapia into shredded fish and fishbone sticks with 5 flavors (original taste, BBQ, spicy sweet, balado, and roasted corn), HPP determining, and marketing diversified products freshwater fish online and offline.
Peningkatan Peran Dewan Kemakmuran Masjid sebagai Fungsi Edukasi dalam Pelaksanaan Kurban di Tengah Pandemi Covid-19
Authors: Arif Ridi , Wicaksono Ardilasunu Wicaksono , Andriyanto Andriyanto , Sholeh Dede
Published: April 2021

The situation of sacrificial day in 1441 H was different from the previous years because it will be held during Covid-19 pandemic situation. The pandemic started in the beginning of 2020 and were not over until the day of sacrifice on July 31, 2020. The government has issued a policy for the day of sacrifices during Covid-19 pandemic situation. Nevertheless, there were still remain problems in the community about the security aspects and the potential spread out of covid-19. This community service activity aims to maximize the role ‘Dewan Kemakmuran Masjid’ (DKM) in conducting education, socialization, and controlling government policies related to the implementation of sacrificial day during pandemic situation. The activity consists of evaluation of the readiness for sacrificial day implementation, preparation of sacrificial education media during the pandemic, and examples of good practices carried out by DKM An-Nashir Mosque, Cihideung Udik Village, Ciampea, Bogor. As many as 40 respondents from various groups and regions in Indonesia participated in an online evaluation to assess their readiness for sacrificial day.  The average point was 7.05 that means people were still poorly prepared while DKM group gets 8.25±1.28 which means it is ready. This shows that DKM was able to educate and serve the community in the implementation of sacrifices during Covid-19 pandemic situation. In addition, in this activity also distributed a link containing material and digital sacrificial pocket books that can be downloaded for free so as to help education on the sacrifice implementation with good and safe practices.
Pelatihan Pengolahan Jamur Tiram untuk Meningkatkan Keterampilan dan Pendapatan Petani Jamur di Desa Tanjung Sangalang
Authors: Panda Adventus , Dirgantara Made , Haryono Agus
Published: April 2021

Sangalang Hapakat Oyster Mushroom Farmers Group is a farmer group specializes in developing oyster mushrooms in Tanjung Sangalang Village, Central Kahayan District, Katingan Regency, Central Kalimantan Province. This farmer group has nine members, which currently sell seeds, baglogs, and oyster mushrooms to the community. To diversify oyster mushroom products and the knowledge of the group is still needed for oyster mushroom post-harvest processing training. Therefore, this service aims to provide training in oyster mushroom processing in product diversification to maximize the benefits obtained. The activity is divided into two stages: processing oyster mushrooms and online marketing of oyster mushroom products. The processing of oyster mushrooms into commercial food products has been successfully carried out at the Sangalang Hapakat Oyster Mushroom Farmers Group, Tanjung Sangalang Village. All farmer groups, especially mothers, can process oyster mushrooms into home food or commercial use. The products produced from this training are crispy mushrooms, mushroom satay, risoles, and shredded mushrooms. Besides, online marketing training provides knowledge to farmer groups in selling their products on various online market platforms and social media. The village's condition, which still has difficulties with internet access, has made the results of this online marketing training less optimal; however, the farmer groups have been able to market their mushroom products online.
Penguatan Kelompok Tani Berbasis Produksi dan Agrowisata Kopi di Kecamatan Way Ratai, Kabupaten Pesawaran, Lampung
Authors: Rusdi Evizal , Prasmatiwi Fembriarti Erry , Sarno Sarno , Nawansih Otik , Miswar Dedy , Septiana Liska Mutiara
Published: April 2021

Lampung Province is the center of Robusta coffee production while Arabica coffee has begun to be developed in the area, including in Harapan Jaya Village, Way Ratai Subdistrict, District of Pesawaran. This village is an ecotourism destination and also has a potential of agrotourism, especially Arabica coffee farming. The objectives of the Community Service Activities are: 1) Increasing knowledge and skills of farmer group members in Arabica coffee agrotechnology; 2) increasing coffee plantation productivity through proper maintenance; and 3) Formulating a model of strengthening farmer group based on coffee agrotourism. This program was carried out at the Karya Subur Farmer Group, in Harapan Jaya Village in year 2018–2019. The methods used are discourse, training, demonstration plots, mentoring, and discussion. The results of this program conclude that: 1) Increasing the knowledge and skills of farmer group members in Arabica coffee agrotechnology; 2) Increasing productivity of coffee plantations plot belonging to the group members assisted; and 3) a model of strengthening of farmer groups based on coffee production and agrotourism is through increasing group capacity in tourism and tourism activities related to the coffee production process from upstream to downstream, increasing accessibility and facilities coordinated with village officials, and increasing agro tourism promotion especially to educational institutions, professionals, and communities.
Reality Check: The Limitations of Artificial Intelligence in Clinical Medicine
Authors: Jones Benjamin , Archer Matt , Germain Stephanie
Published: April 2021

ABSTRACT

Artificial intelligence is poised to transform clinical medicine, yet for successful implementation to occur we must also appreciate its limitations. The heterogeneity of current research, particularly in relation to the use of data, means that results cannot necessarily be extrapolated to a population level. Robust study designs are required to minimise the introduction of bias into artificial intelligence models and generate a strong body of evidence. Identifying the specific areas of healthcare where artificial intelligence can have the greatest impact will be essential in ensuring it has a positive influence on clinical outcomes and patient experience over the coming years.
ЭКСПЕРИМЕНТАЛЬНЫЕ ИССЛЕДОВАНИЯ ИНФРАКРАСНОЙ ГОРЕЛКИ С ПОВЕРХНОСТНЫМ РЕЖИМОМ ГОРЕНИЯ В ОБЛАСТИ ВЫСОКИХ ЗНАЧЕНИЙ УДЕЛЬНОЙ МОЩНОСТИ ГОРЕНИЯ
Authors:   Федеральный исследовательский центр химической физики им. Н.Н. Семёнова Российской академии наук, ВАСИЛИК Н.Я. , ЗАХАРОВ А.А. ,   Федеральный исследовательский центр химической физики им. Н.Н. Семёнова Российской академии наук
Published: April 2021

Проведены экспериментальные исследования процесса горения смесей природного газа с воздухом в инфракрасном (ИК) горелочном устройстве, работающем в режиме вынужденного поверхностного горения (ВПГ) вблизи поверхности системы пластин из жаростойкого металлического сплава ПХ25Ю6. Конструкция горелкии режим ВПГ позволили реализовать устойчивый режим поверхностного горения в области значений удельной мощности горения от 900 до 5800 кВт/м2 на единицу площади поперечного сечения газового потока. Мощность горелки изменялась в интервале от 10,7 до 24 кВт. Габариты системы излучающих пластин горелки: ширина 72 мм; длина 90 мм; высота 110 мм. Концентрация оксидов азота в продуктах сгорания не более 11 ppm, концентрация моноксида углерода не более 10 ppm при значениях коэффициента избытка воздуха 1,5 и мощности не более 20 кВт. Максимальная температура внешней поверхности излучающих пластин 1280 ◦C.
ЭКСПЕРИМЕНТАЛЬНОЕ ИССЛЕДОВАНИЕ ОБЖИГОВОЙ ПЕЧИ НА ПРИНЦИПЕ ФИЛЬТРАЦИОННОГО ГОРЕНИЯ ГАЗОВ
Authors:   Томский научный центр Сибирского отделения Российской академии наук, КИРДЯШКИН А.И. , ГАББАСОВ Р.М. ,   Томский научный центр Сибирского отделения Российской академии наук, КИТЛЕР В.Д. ,   Томский научный центр Сибирского отделения Российской академии наук, МАЗНОЙ А.С. ,   Томский научный центр Сибирского отделения Российской академии наук
Published: April 2021

Разработка энергоэффективных высокотемпературных печей важна для удешевления производства изделий из тугоплавких керамических материалов. В данной работе экспериментально изучен прототип печи, в которой объем камеры заполнен засыпкой керамических шаров, а источником энергии является горение предварительно перемешанных смесей природного газа с воздухом и кислородом. Архитектура печи позволяет применять два режима горения: (1) фильтрационное горение, когда узкая реакционная зона (волна горения) свободно распространяется по засыпке; (2) принудительная газодинамическая стабилизация зоны горения вблизи отверстий ввода смеси в объем засыпки. С помощью методов термопарного и спектрометрического измерения температуры экспериментально исследованы режимы работы печи в диапазоне удельных расходов природного газа от 7 до 107 нл/с/м2 , коэффициента избытка топлива от 0,4 до 3,3, концентрации кислорода в окислителе от 21 до 30 %(об.). В данных диапазонах обеспечена регулировка температуры засыпки от 1230 до 2220 К. При температуре 2170 K проведено тестовое спекание порошковых образцов из оксида магния, оксида алюминия и шпинели MgAl2 O4 . Установлено, что спекание в режиме движущейся волны горения эффективно для получения изделий с характерным размером до 10 мм. В этом случае засыпка может быть полностью сформирована из образцов, которые подлежат спеканию. Режим принудительной стабилизации эффективен для спекания крупноформатных изделий. Новая печь на принципах горения природного газа в пористой инертной среде может быть востребована для мелкосерийного изготовления керамических изделий.
ОБЪЯСНЕНИЕ РОСТА СКОРОСТИ САМОПОДДЕРЖИВАЮЩЕЙСЯ ДЕТОНАЦИИ ПРИ ЕЕ РАСПРОСТРАНЕНИИ ВВЕРХ ПО ПОТОКУ В КАНАЛЕ С ПОГРАНИЧНЫМИ СЛОЯМИ
Authors:   Центральный аэрогидродинамический институт (ЦАГИ), САБЕЛЬНИКОВ В.А. , ВЛАСЕНКО В.В. ,   Центральный аэрогидродинамический институт (ЦАГИ),   Московский физико-технический институт (МФТИ), МОЛЕВ С.С. ,   Центральный аэрогидродинамический институт (ЦАГИ), ТРОШИН А.И. ,   Центральный аэрогидродинамический институт (ЦАГИ),   Московский физико-технический институт (МФТИ), БАХНЭ С. ,   Центральный аэрогидродинамический институт (ЦАГИ),   Московский физико-технический институт (МФТИ)
Published: April 2021

При помощи численного моделирования исследована газодинамическая структура детонационной волны, распространяющейся против сверхзвукового потока в канале с пограничными слоями. Исследование основано на классических экспериментах J. C. Bellet и G. Deshayes (1970), которые показали, что при формировании структуры с отрывами пограничных слоев и детонационным диском Маха скорость детонационной волны по отношению к свежей горючей смеси существенно превосходит скорость одномерной (1D) детонации Чепмена-Жуге (ЧЖ). Дан анализ газодинамической структуры детонационной волны, выявлен и объяснен механизм увеличения скорости детонации. Совместное воздействие зоны отрыва пограничного слоя и вторичной детонационной волны приводит к образованию газодинамического сопла Лаваля с запиранием потока за детонационным диском Маха. Показано, что рассматриваемое течение можно отнести к классу двухслойных самоподдерживающихся детонаций. Рассмотрено влияние тепловых потоков, трехмерных (3D) эффектов и турбулентности на скорость волны.
ВЛИЯНИЕ ДОБАВОК CUSO4 * 5H2О, FESO4 * 10H2O, NA2В4О7 * IOH2O И CUSO4 НА ЗАКОНОМЕРНОСТИ ГОРЕНИЯ ПОРОШКА МАГНИЯ НА ВОЗДУХЕ
Authors:   Федеральный исследовательский центр химической физики им. Н.Н. Семёнова Российской академии наук, КРУПКИН В.Г. , МОХИН Г.Н. ,   Федеральный исследовательский центр химической физики им. Н.Н. Семёнова Российской академии наук
Published: April 2021

Проведено исследование особенностей горения на воздухе цилиндрических образцов из порошка магния насыпной плотности с различными добавками - безводной сернокислой медью, оксидом железа и кристаллогидратами CuSO4 * 5H2O, FeSO4 * I0H2O и Na2В4O7 * I0H2O. Показано, что введение в состав порошка магния добавки в количестве более 2%(вес.) приводит к режиму горения образца при характерной температуре ~ 1100 ◦С. Степень превращения магния в остатке после сгорания в этом режиме близка к 100%. Конкретный состав добавки и ее количество существенно не влияют на характер временной зависимости температуры образца при его горении. Остаток после сгорания образцов в воздухе состоит из смеси оксида и нитрида магния. Соотношение между массой исходного образца и массой остатка после его сгорания позволяет оценить состав остатка. Полученные результаты объясняются появлением в зоне прогрева при распространении пламени по образцу горячих очагов, вызванных реакцией добавки с магнием, дополнительным разогревом этими очагами образца и выходом режима горения на плато с температурой ~ 1100 ◦С, соответствующей температуре кипения магния в частицах исходного порошка. Испарение магния в этом режиме стабилизирует процесс его горения.
ИССЛЕДОВАНИЕ ВЛИЯНИЯ ТЕРМИЧЕСКИХ ПРЕВРАЩЕНИЙ КОМПОНЕНТОВ ВСПЕНИВАЕМЫХ КОМПОЗИЦИЙ НА ИХ ОГНЕТЕРМОЗАЩИТНЫЕ СВОЙСТВА
Authors:   Учреждение Белорусского государственного университета «Научно-исследовательский институт физико-химических проблем» (НИИ ФХП БГУ), г.Минск, БОГДАНОВА В.В. , КОБЕЦ О.И. ,   Учреждение Белорусского государственного университета «Научно-исследовательский институт физико-химических проблем» (НИИ ФХП БГУ), г.Минск
Published: April 2021

Проведены сопоставительные исследования качественного и количественного состава вспениваемых графитсодержащих композиций на основе сополимера этилена с винилацетатом (СЭВА) и определена важная роль минеральных наполнителей в образовании термоизолирующих пористых структур. В качестве наполнителей в композициях использованы минеральные силикаты, терморасширяющийся графит (ТРГ) и/или огнезамедлительные газококсообразующие системы (ГКС), включающие амин, металл- и/или фосфор-содержащие соединения. Для исследования физико-химических, эксплуатационных, термических и огнетермоизолирующих свойств использованы стандартные и оригинальные лабораторные методики. Установлено, что требуемые огнетермоизолирующие и эксплуатационные свойства вспениваемых композиций, содержащих ТРГ, могут быть достигнуты сбалансированным присутствием в их рецептуре инертных силикатных и газококсообразующих агентов. Оптимизация рецептуры позволяет одновременно улучшить эластичные и прочностные свойства как исходных термовспениваемых композиций (ТВК), так и их коксовых остатков.
Персонализированный подход к повышению эффективности и безопасности терапии артериальной гипертензии эналаприлом
Authors: Прокофьев А. Б. , Журавлева М. В. , Дмитриев Артем И. , Белков Сергей А. , Мельников Евгений С. , Родина Татьяна А. , Данько Андрей А. , Городецкая Галина И.
Published: April 2021

Изучен метаболизм эналаприла у больных артериальной гипертензией в зависимости от величины назначенной дозы препарата, скорости клубочковой фильтрации и индекса массы тела для повышения эффективности и безопасности лечения. Проведено исследование концентрации эналаприла и эналаприлата в плазме крови у 206 больных (86 мужчин и 120 женщин в возрасте от 48 до 84 лет), поступивших на лечение по поводу артериальной гипертензии 1 – 2 степени. Выполнен терапевтический лекарственный мониторинг после назначения эналаприла больным. Выделены группы пациентов: с медленным метаболизмом — 12 человек (6 %) из них 2 мужчин (1 %) и 10 женщин (5 %); с быстрым метаболизмом — 28 человек (14 %) из них 8 мужчин (4 %) и 20 женщин (10 %), и с нормальным метаболизмом — 166 человек (80 %), из них 62 мужчины (30 %) и 104 женщины (50 %). Статистически значимых гендерных различий в группах больных с быстрым и медленным метаболизмом препарата не выявлено. Показано, что снижение скорости клубочковой фильтрации (менее 60 мл/мин) приводит к увеличению концентрации эналаприлата в 1,9 раза (p = 0,004). Установлено отсутствие влияния величины индекса массы тела на концентрации эналаприла и эналаприлата в плазме крови пациентов. Проведённое исследование подтверждает, что эффективность и безопасность терапии артериальной гипертензии эналаприлом зависит от индивидуальных особенностей метаболизма, а также от скорости клубочковой фильтрации.
Влияние эссенциале н на выживаемость крыс при воздействии продольных перегрузок «голова-таз» (+Gz) и острой гипоксической гипоксии
Authors: Чернов Юрий Николаевич , Васин Михаил Витальевич , Ушаков Игорь Борисович
Published: April 2021

Опыты проведены на 86 беспородных белых крысах. Животных подвергали воздействию продольных «голова-таз» перегрузок (+Gz) величиной 2 ед в течение 2 мин или острой гипоксической гипоксии при «подъеме на высоту» 10,5 км при скорости подъема 20 м/с и нахождении на «площадке» 10,5 км в течение 30 мин. Препарат Эссенциале Н в виде раствора, содержащего фосфатидилхолин, никотинамид, цианкобаламин, пиридоксин и натрий-d-пантотенат, вводили крысам внутрибрюшинно в дозе 4 мл/кг (200 мг/кг по содержанию в препарате фосфолипидов и 20 мг/кг никотинамида) за 15 – 20 мин до воздействия экстремальных факторов. Применение эссенциале Н сопровождалось снижением числа погибших под воздействием продольных перегрузок «голова-таз» (+Gz) и острой гипоксической гипоксии крыс на 31 и 60 %, соответственно (p < 0,05).
Analysis of Interleukin-4 in Thrombocytopenia Autoimmune Patients
Authors: Nurfaizah Sitti , Arief Mansyur , Bahrun Uleng
Published: April 2021

Thrombocytopenia is a disease characterized by a decreased platelet count. Some of the causes are decreased platelet production, increased platelet use, such as due to infection, and autoimmune causes, namely the loss of tolerance of the immune system to self-antigens on the surface of the platelets and megakaryocytes marked with a platelet count <100,000 / μL and based on the pathomechanism classified as primary Immune Thrombocytopenia (ITP) and secondary, as well as several other causes. IL-4, one of the cytokines produced by Th2 which stimulates B cells to increase antibody production. The aim of this study was to compare IL-4 levels in primary ITP patients and non-primary ITP tombocytopenia. This study involved 30 primary ITP subjects and 30 non-ITP primary tombocytopenia subjects obtained based on data medical records, examination of IL-4 cytokine levels by the ELISA method. The results of this study that the IL-4 levels of the primary non ITP tombocytopenia subject group were higher than the primary ITP subject group, which means that there were differences in IL-4 levels in the primary ITP subject group and the non-ITP primary tombocytopenia subject group.
The Effectiveness of Red Grape (Vitis vinifera) Seed and Skin Extract Treatment on Staphylococcus aureus Bacteria that Causes of Urinary Tract Infections in Pregnant Women Examined by using White Mice (Mus musculus)
Authors: Liastra Satriya Manggala , Ariningtyas Ninuk Dwi , Levani Yelvi
Published: April 2021

Urinary tract infection or what is often called a UTI is an infectious disease of the urinary tract epithelium and is commonly caused by gram-positive bacteria, namely the Staphylococcus aureus, with a prevalence rate of 68 million patients in the world and 1.2 million patients in Indonesia. The diagnosis of UTI is established with a positive urine culture significance value ≥105 (CFU)/ml. The existing clinical management for cases of urinary tract infections in pregnant women uses amoxicillin to kill gram-positive bacteria, such as Staphylococcus aureus. However, there have been 469 cases of antibiotic resistance in pregnant women in Indonesia due to the non-compliance of using antibiotics for urinary tract infections. Vitis vinifera can be used as an alternative to natural bactericidal resveratrol containing anthocyanidin to kill gram-positive bacteria. This study used 28 white mice (Mus musculus) aged 6-21 weeks and weighing 120-200 grams injected with Staphylococcus aureus. The 28 subjects were divided into 4 groups, each of which consisted of 7 mice. The mice received K1 treatment with 250 mg/kgBW of amoxicillin and treatments with 200, 300, and 500 mg/KgBW red grape seed and skin extract. Before treatments were given, a pre-test was conducted to ensure that the results were not biased. Post-test was also performed after the Staphylococcus aureus injection, which was measured after 5 days of urine culture that reached 107 CFU/ml. The treatment in P3 using 500 mg/KgBW of red grape seed and skin extract contributed to the smallest result with 102 Cfu/ml, equals to the result produced by giving 250 ml/KgBW of amoxicillin.
Prevalence of Listeria spp. with PRS Genes in Fresh Vegetables from Traditional Markets
Authors: Putra A. Kaisar Adiwijaya , Sjahril Rizalinda , Santoso Arif , Amiruddin Dianawaty , Zainuddin Andi Alfian , Hamid Firdaus
Published: April 2021

Listeriosis is a foodborne infectious disease caused by Listeria monocytogenes and is considered a serious health problem, due to the severity of symptoms and a high mortality rate in worldwide This study aims to identify and determine the prevalence of Listeria species through prs gene screening of fresh vegetables distributed in several markets of Makassar City. A total of 57 fresh vegetable samples were collected from February to May 2019 in four traditional markets Makassar. The isolates is examines to phenotypically and genotypically Vitek and Multiplex PCR with prs and lmo1030 primer. Phenotype analysis did not show the presence of Listeria species, but the results of genotypic was found 8 positive prs gene samples (14.03%), consisting of 31.2% long beans, 18.2% cabbage, and 9.1% cucumber and. All Listeria species found in this study is Listeria monocytogenes. This study also provide information and additional data that prs genes can be used as screening genotype for identify Listeria species in fresh vegetables.
House Dust Mites in One of Indonesian Detention Center in 2020
Authors: Malia Ajrina , Jamilatun Makhabbah , Aminah Aminah
Published: April 2021

House dust mite was one of the most common allergens in homes around the world and associated with manifestations of allergies of skin and respiratory tract such as bronchial asthma, allergic rhinitis, and atopic dermatitis. This arthropod was commonly found on carpets, mattresses, children's toys, and other home furnishings. This study was aimed to identify and quantify the number of Dermatophagoides spp in Detention Center. This descriptive study was conducted using flotation method on 52 samples of mattress dust collected in February 2020. The results showed that 49 out of 52 mattress dust samples were positive of Dermatophagoidesspp..Of all Dermatophagoides spp, there were Dermatophagoides pteronyssinus (71.2%) and Dermatophagoides farinae (28.8%). In conclusion, this study found two species of Dermatophagoides spp. in Detention Center and suggested that the fascility maintain the cleanliness of the mattress by drying the mattress and changing the sheets at least once a week.
The Screening of Antioxidant Activities of Meniran Plants (Phyllanthus niruri Linn) and Guava Leaves (Psidium guajava Linn) Combination Using DPPH Free Radical Method
Authors: Wimpy Wimpy , Harningsih Tri , Sisvitara Yesti Nanda
Published: April 2021

Degenerative disease is a serious health problem and causes a lot of deaths in Indonesia. One of the most dangerous degenerative diseases is cancer. Free radicals play a role in oxidative stress in the later stages of carcinogenesis. Antioxidant delays or inhibits cellular damage mainly through its free radical scavenging property. Meniran plants and guava leaves have high radical-scavenging activities. The previous studies reported that the combination of ginger and Meniran plant extract has a stronger antioxidant activity than the extract of a single plant. This research aims at determining the antioxidant activities of Meniran plants and guava leaves compared with its singular form. This research was conducted from October to December 2016 at the Chemical Laboratory of Nasional Health Science Institute and the Center for Development and Research of Medicinal Plants and Traditional Medicine, Tawangmangu, Karanganyar. The antioxidant activity assay was done using DPPH free radical method and vitamin C was used as the control. They were measured with UV-Vis Spectrophotometer. This study concludes that the IC50 value of Meniran plants was 30.689 ppm and the IC50 value of guava leaves was 13.7859. The IC50 values of Meniran plant and guava leaf combination with various ratios were 20.6095 ppm (1:1), 12.5629 ppm (1:2), and 16.841 ppm (2:1). The combination of Meniran plant and guava leaf extract (1: 2) had the strongest antioxidant activity of 12.56 ppm.
The Measurement of Antioxidant Activity of Velvet Beans (Mucuna pruriens) and Velvet Beans (Mucuna pruriens) in Coffee Preparations
Authors: Susilowati Indah Tri , Purwati Purwati
Published: April 2021

Antioxidant activity tests of methanol extracts of velvet beans (Mucuna pruriens) and velvet beans (Mucuna pruriens) in coffee preparations have been previously carried out by several researchers. This present study aims to examine the phytochemical and antioxidant activities of methanol extracts of Mucuna pruriens and Mucuna pruriens in coffee preparations. The methanol extract was tested for the phytochemical and antioxidant activities by applying DPPH (1,1-Dhiphenyl-2-picrylhydrazil) method. The results of the phytochemical test showed that the methanol extracts of the Mucuna pruriens and Mucuna pruriens in coffee preparations contained secondary metabolites of flavonoids, alkaloids, saponins, terpenoids, and tannins. The outcomes of the antioxidant activity test revealed that the methanol extracts of the Mucuna pruriens and Mucuna pruriens in coffee preparations had antioxidant activities, as indicated by the IC50 values of 42.09 ppm and 37.23 ppm. It was also revealed that the antioxidant content of Mucuna pruriens in coffee preparations was stronger than the content in the velvet beans alone.
Lemongrass (Cymbopogon Citratus) Essential Oil Inhibits Candida Albicans Growth in Vitro
Authors: Pratama Yoga Mulia , Permana Bryan Pandu
Published: April 2021

Candidiasis is an important nosocomial infection with high morbidity value, high mortality rate, and expensive clinical cost. However, public access to well-developed treatment is not acquired. Current medicines mostly used like -azol drugs had been showing the resistant effects because of the long period use of the same medicines. Alternative medicines like herb medicine are discussed to reduce multi-resist infections, such as lemongrass Cymbopogon citratus essential oil. This study aims to know the effect of lemongrass essential oil on the growth of Candida albicans in vitro. Laboratory experimental (in vitro) was conducted in this research. Candida albicans strains were being used as the objects, which were picked by random sampling. Candida albicans were divided into 12 groups of treatment, the group I was treated with ethanol 96% as the negative control, group II with fluconazole 25μg as the positive control, and group III-XII with Cymbopogon citratus essential oil with 10%, 20% to 100% concentrated. The diameter of inhibition zones was measured after 2x24 hours incubation. The data was analyzed by post-hoc Mann Whitney test with SPSS 18.0 (p<0.05 considered as significant). Cymbopogon citratus essential oil showed antifungal activity to the Candida albicans began in the 10% to 100% concentration (p<0.05). Inhibition zones with the 50% to 100% concentration had similar results to the positive control (p>0.05). The Cymbopogon citratus essential oil has an antifungi effect toward Candida albicans in vitro significantly by the negative control.
Intensification the Role of Parent for Learning Assistance Model at Home in The New Normal Era
Authors: Sujarwo Sujarwo , Kusumawardani Erma , Prasetyo Iis , Ariyanti Dewi Adin
Published: April 2021

This activity aims to carry out a model of children's learning assistance through optimizing the role of parents to be more enthusiastic in facing this new normal era. Not a few parent feel confused and difficult in assisting their children in learning. This research used participatory action research method. The program target of this activity is 30 parent and 15 facilitator from ‘keluarga harapan’ program. It can be seen that the activities carried out have optimized various parties and can achieve the expected output. Based on the activity , beneficiary families are motivated and have high enthusiasm in spreading the knowledge and skills they have acquired to other families. So, from this activity the community service team highlighted several important things that have been done starting from paying attention to the concept of adult learning, strengthening the focus on social capital and also introducing the importance of peer teaching
The Relevance of Good Corporate Governance Practices to Bank Performance
Authors:   CamEd Business School (Cambodia), Ma’aji Muhammad M. , Anderson Ediri O. , Colon Christine G.
Published: April 2021

The purpose of this paper is to examine how corporate governance instruments impact firm value in the context of Cambodian banks. This paper considers foreign and domestic-owned banks in Cambodia. This study opts for a balanced sample of foreign and domestic owned banks for the period 2014-2018. Panel data regression is adopted for estimation of main results. The suitable model, i.e. fixed and random effect model is selected using the Hausman specification test where the result shows that the random effect model using generalized least square (GLS) regression is more suitable for the analysis. The findings show that Cambodian banks are having a substantially higher percentage of NEDs on their board, high implementation of governance procedures on board committees where on average the banks are having more than the required two board committees (audit and risk committees) as required by the Prakas on the governance of banks by National Bank of Cambodia. The average board size is around 8 members of which at least 3 members are having a postgraduate degree or a professional qualification. Policymakers need to improve on their supervisory function as the majority of the domestic and some foreign banks do not disclose their annual reports on their company website as required by the Prakas on Corporate Governance of Banks operating in Cambodia. Moreover, amendments should be made to the current corporate governance code for financial institutions as there are no explanatory notes that guide companies and therefore, the current guideline is open to individual and subjective interpretation.
Choice of Response Strategy Adopted by Indian Private Higher Education Institutions Collaborated with Foreign Education Institutions: Applying Porter’s Five Force Model
Authors:   National Institute for Educational Planning and Administration (India), Jaiswal Laxmi
Published: April 2021

Market follows the profit and compete for the resources to get competitive advantage that is inevitable. Private higher education institutions in India collaborate with foreign education providers to deliver education services in variety of modes for enlarging the student share in the market. Applying Porter’s Five Force Model it was analysed how the institutions in NCR of India position themselves in the market forces and strategise to get comparative advantage. India with huge size of middle class and vast system of higher education always attract the foreign institutions to collaborate and expand. The restrictive and proscriptive regulation does not allow foreign qualification in India except twinning mode. The finding of the present analysis using porter’s five force model suggest that regulation of the state must be comprehensive and supportive to encash the flow of market innovations that happen to be. Thoughtful regulatory framework may reap the benefit other wise institutions under market forces offer unrecognised foreign degree in informal way under the orbit of formal institution that motivate less quality tier II and III institutions to supply educational services disguising under formal system of higher education.
Influence of Demonstration Methods and Student’s Activity on Learning Outcomes
Authors:   Sekolah Tinggi Ilmu Kesehatan Garuda Putih Jambi (Indonesia), Universitas Bengkulu (Indonesia), Institut Agama Islam Negeri Bengkulu (Indonesia), Purdiyanto Purdiyanto , Sasongko Rambat Nur , Kristiawan Muhammad , Walid Ahmad , Kusumah Raden Gamal Tamrin
Published: April 2021

This research is motivated by the fact in the field that the fourth-grade students' mathematics learning outcomes are still low in Public Elementery School 16 Bengkulu City. This is presumably, the lack of application of demonstration methods and student activeness towards student learning outcomes. On this basis, this study is focused on discussing mathematics learning using demonstration methods. The problem of this research is the low student learning outcomes and the students' lack of understanding of the broad and perimeter material. The purpose of this study was to determine the effect of demonstration methods and student activeness on mathematics learning outcomes of fourth-grade students of SD Negeri 16 Bengkulu City. This type of research is a quantitative study with an experimental method approach. Data collection techniques using observation, tests and documentation. The data analysis technique used the t test. The result of this research is the demonstration method and student activeness have a significant effect. So it can be concluded that the higher the student's activity, the higher the learning outcomes and the demonstration method as well as the learning outcomes, which means that the working hypothesis (Ha) in this study is accepted, that is, there are differences in student activeness in the control and experimental classes.
How Successful Are We Aging?
Authors: POLAT Filiz , DELİBAŞ Leyla
Published: April 2021

Aim: This study was conducted to determine who live in southeastern Turkey, the older people how successful they get older.Methods: The sample of the descriptive study; it consisted of 442 elderly individuals aged 60 and over who applied to two Family Health Centers (FHC) between July and October 2019. Personal Information Form and Successful Aging Scale were used to collect data. Percentage, frequency, average, standard deviation, linear regresyon, t test and Anova were performed in the data analysis (p<0.05).Results: It was determined that the mean scores of Successful Aging Scale decreased with increasing age, increased with education and the difference between them was significant (p=0.00). It was determined that Successful Aging Scale total scale mean score was 46.5±12.0. The effect of independent variables on successful aging was determined as R2 = .262.Conclusion: It was determined that total mean score of successful aging of the elderly individuals included in the study was medium, and as the age increased, the mean score of successful aging decreased.
Realizing the problem wasn’t necessarily me": The meaning of childhood adversity and resilience in the lives of autistic adults
Authors: Heselton Gabrielle A. , Rempel Gwen R. , Nicholas David B
Published: April 2021

Interview Data
There is ample evidence that childhood adversity
correlates negatively with physical and mental health outcomes across the
lifespan. Resilience results when internal and external protective factors in
childhood mitigate the effects of adversity and mental and physical health
outcomes are improved. However, the phenomena of childhood adversity and
resilience among autistic children are understudied and not well understood. In
this study, we engaged members of the autism community to advise on the
research question, research design, and analysis. Following the engagement
phase, three autistic young women and one nonbinary young adult, aged 19-27,
participated in semi-structured interviews via phone, video conference, and
online chat;. credibility checking interviews followed data analysis. Through
interpretative phenomenological analysis we identified themes related to
negative effects of adversity, including social disconnection, mental
and emotional well-being, sense of self, and development into
young adulthood. Resilience was developed in places of refuge and identity,
and was evident in their transitions into young adulthood. These
findings provide direction for fostering resilience in children and adolescents
on the autism spectrum and planning and implementing mental health supports to
autistic individuals across the lifespan.