bluuebunny/crossref_metadata_2025 huggingface dataset:
Applications of Web Scraping in Economics and Finance
Authors: Śpiewanowski Piotr , Talavera Oleksandr , Vi Linh
Published: December 2021

The 21st-century economy is increasingly built around data. Firms and individuals upload and store enormous amount of data. Most of the produced data is stored on private servers, but a considerable part is made publicly available across the 1.83 billion websites available online. These data can be accessed by researchers using web-scraping techniques.

Web scraping refers to the process of collecting data from web pages either manually or using automation tools or specialized software. Web scraping is possible and relatively simple thanks to the regular structure of the code used for websites designed to be displayed in web browsers. Websites built with HTML can be scraped using standard text-mining tools, either scripts in popular (statistical) programming languages such as Python, Stata, R, or stand-alone dedicated web-scraping tools. Some of those tools do not even require any prior programming skills.

Since about 2010, with the omnipresence of social and economic activities on the Internet, web scraping has become increasingly more popular among academic researchers. In contrast to proprietary data, which might not be feasible due to substantial costs, web scraping can make interesting data sources accessible to everyone.

Thanks to web scraping, the data are now available in real time and with significantly more details than what has been traditionally offered by statistical offices or commercial data vendors. In fact, many statistical offices have started using web-scraped data, for example, for calculating price indices. Data collected through web scraping has been used in numerous economic and finance projects and can easily complement traditional data sources.
Drowning: Global Burden, Risk Factors, and Prevention Strategies
Authors: Rahman Aminur , Peden Amy E. , Ashraf Lamisa , Ryan Daniel , Bhuiyan Al-Amin , Beerman Stephen
Published: December 2021

Drowning has been described as a major global public health problem and has recently been acknowledged by a United Nations Declaration on Global Drowning Prevention. While drowning impacts countries of all income levels, the burden is overwhelmingly borne by low- and middle-income countries (LMICs) who account for 90% of the global death toll. In addition, there is scarce data collection on drowning in LMICs, so the magnitude of drowning may be far greater than is represented. A range of factors including sex, age, education, income, access to water, a lack of swimming skills, certain occupations like commercial fishing, geographically isolated and flood-prone locations, preexisting medical conditions, and unsafe water transport systems, influence the risk of drowning. Some behavioral factors, such as alcohol or drug consumption, not wearing life jackets, and engaging in risky behaviors such as swimming or boating alone, increase drowning risk. Geopolitical factors such as migration and armed conflict can also impact drowning risk. There is a growing body of evidence on drowning prevention strategies. These include pre-event interventions such as pool fencing, enhancing community education and awareness, providing swimming lessons, use of lifejackets, close supervision of children by adults, and boating regulations. Interventions to reduce harm from drowning include appropriate training for recognition of a drowning event, rescue, and resuscitation. An active and/or passive surveillance system for drowning, focusing on individual settings and targeting populations at risk, is required.

Drowning requires coordinated multisectoral action to provide effective prevention, rescue, and treatment. Therefore, all countries should aim to develop a national water safety plan, as recommended in the WHO Global Report on Drowning. Further research is required on the epidemiology and treatment of drowning in LMICs as well as non-fatal and intentional drowning in both high-income countries (HICs) and LMICs. Effective and context-specific implementation of drowning prevention strategies, including pilot testing, scale up and evaluation, are likely to help reduce the burden of both fatal and non-fatal drowning in all countries.
Migration, Migrants, and Health in Latin America and the Caribbean
Authors: Ventura Deisy , Martins da Silva Jameson , Calderón Leticia , Eguiluz Itzel
Published: December 2021

The World Health Organization has recognized health as a right of migrants and refugees, who are entitled to responsive healthcare policies, due to their particular social determinants of health. Migrants’ and refugees’ health is not only related to transmissible diseases but also to mental health, sexual and reproductive health, and non-communicable diseases, such as diabetes. Historically, however, migration has been linked to the spread of diseases and has often artificially served as a scapegoat to local shortcomings, feeding on the xenophobic rhetoric of extremist groups and political leaders. This approach fosters the criminalization of migrants, which has led to unacceptable violations of human rights, as demonstrated by the massive incarceration and deportation policies in developed countries, for example, the United States under the Trump administration.

In Latin America and the Caribbean, in particular, there have been legal developments, such as pioneering national legislation in Argentina in 2004 and Brazil in 2017, which suggest some progress in the direction of human rights, although in practice drawbacks abound in the form of countless barriers for migrants to access and benefit from healthcare services in the context of political turmoil and severe socioeconomic inequality. The COVID-19 pandemic has exposed and enhanced the effects of such inequality in the already frail health conditions of the most disenfranchised, including low-income migrants and refugees; it has both caused governments in Latin America to handle the crisis in a fragmented and unilateral fashion, ignoring opportunities to cooperate and shield the livelihoods of the most vulnerable, and served as a pretext to sharpen the restrictions to cross-border movement and, ultimately, undermine the obligation to protect the dignity of migrants, as the cases of Venezuela and the U.S.-Mexico border illustrate. Still, it could represent an opportunity to integrate the health of migrants to the public health agenda as well as restore cooperation mechanisms building on previous experiences and the existing framework of human rights organizations.
Space Law: Overview
Authors: Lyall Francis
Published: December 2021

Space law is composed of disparate elements of ordinary national laws and general international law. It has been created by the agreement of states as to the international law that should govern important technical and technological developments of the later 20th and the 21st century. That agreement is expressed in five general treaties; other treaty-level measures including as to the use of radio, declarations of principle, recommendations on the conduct of space activities, and by state practice. The United Nations Committee on the Peaceful Uses of Outer Space (COPUOS), serviced by the UN Office of Outer Space Affairs (UNOOSA), plays a significant role in the development of the many aspects of space law, as do intergovernmental and nongovernmental agreements together with informal arrangements between space-active bodies.
Kurdish Politics in the Global Context
Authors: Al Serhun
Published: December 2021

Kurds are considered to be one of the largest ethnic groups in the world—with a population of more than 30 million people—who do not have their own independent state. In the Middle East, they are the fourth largest ethnic group after Arabs, Persians, and Turks. The statelessness of such a major group with an increasing ethnic and national consciousness in the post-Ottoman world led to their traumatic insecurities in the hands of majority-led nation-states that used modern technologies of social engineering including displacement, dehumanization, assimilation, and genocidal acts throughout the 20th century. With the memory of such traumatic insecurities, the driving force of contemporary Kurdish nationalism in the Middle East has primarily been the question of state or state-like entities. Yet, Kurds are not a homogeneous group with a collective understanding of security and self-government. Rather, there are political-organizational rivalries within Kurds across Iraq, Syria, Turkey, and Iran. Thus, it is important to understand the multifaceted Kurdish politics in the Middle East within a global-historical perspective where global power rivalries, regional geopolitics, and intra-Kurdish organizational competition are interwoven together. While the opportunities for Kurdish self-determination were missed in the early 20th century, resilient Kurdish political organizations emerged within the bipolar international context of the Cold War. The American hegemony in the post–Cold War era transformed the Kurdish political status in the geopolitics of the Middle East, where the 1991 Gulf War, the 2003 Iraq War, and the broader war on terror provided the Kurds with many political opportunities. Finally, the shifting regional and global alliances in the post–Arab Spring era—where the Islamic State of Iraq and Syria (ISIS) has become the global nemesis—created new political opportunities as well as significant threats for the Kurds.
Scales of Observation
Authors: Desjeux Dominique
Published: December 2021

One of the particularities of applied anthropology is working on demand, and performing research on demand requires changing fields constantly. This diversity of fields has led to an awareness in applied anthropology that the focal point of observation varies from study to study, and that depending on the particular scope or decoupage, researchers do not see the same thing. This scales-of-observation method has four empirical principles: (a) What one observes at one scale vanishes at another scale. (b) The causes explaining actors’ behavior vary based on the scale of observation; they can stem from situational effects or meaning effects, or suggest statistical correlation. (c) Knowledge acquired at one scale is complementary and cumulative with that of other scales of observation. However, they cannot be fused into a single, global description. Indeed, although reality is continuous, observation between the “macro” and the “micro” is discontinuous. Discontinuity stems from the importance of the situational effects in anthropology and organizational sociology. These two approaches are most often centered on the interactions among actors operating under situational constraints. All generalizations are thus limited to scales pertaining to the same type of causality. (d) Part of the conflict among schools, disciplines, or professions regarding explanations for human behavior and changes within a community, an organization, a society, or an individual can most often be explained by different choices in the scale of observation. The scales-of-observation method is a mobile tool of knowledge founded on the anthropological practice of the cultural detour, in this case scientific cultures. It is an inductive epistemological theory on the variability of the explanatory causes of human behavior and falls under methodological relativism. Consequently, the scales-of-observation method is also a tool of negotiation among actors who are involved collectively in a project of social change, but with contradictory interests or objectives.
The Legal Frameworks of Protecting Archaeology in Africa
Authors: Katsamudanga Ancila
Published: December 2021

Archaeological heritage is fragile and nonrenewable. In Africa, it is vulnerable to developmental projects in construction, mining, and agriculture as well as intentional and unintentional vandalism through everyday use and tourism. Looting, illegal trade of antiquities, and terrorism have also emerged as other significant threats to archaeological heritage in Africa. Looting and vandalism of sites and objects result from lax monitoring mechanisms and a general lack of awareness of archaeological matters among the public. Although most African countries have the legal protection of archaeological heritage, the effectiveness of these has been under question. African heritage legislations have been criticized for the lack of predevelopment assessments that would ensure the protection of recorded and unrecorded archaeological heritage. They have also been censured for protecting just the physical aspects of archaeological heritage, leaving out the intangible aspects that actually give the heritage value, especially among African communities. Another challenge was the exclusion of local communities and customary management systems in the protection of archaeological heritage. Provisions for counteracting looting and illegal trade in antiquities, coming especially from archaeological sites, were also considered weak and requiring improvements.

The response to the debate on the effectiveness of the legal protection of heritage has been varied across the continent. Some African countries have responded by writing new laws, amending old ones, or providing other supporting legal provisions such as national cultural policies or regulations. Countries that have instituted new legal provisions include Namibia, Botswana, Kenya, Mali, Egypt, Mauritania, and the Republic of the Congo. Those who reworked their protective mechanisms have attempted to address many of the issues raised. Countries such as Namibia, Botswana, and Mali have included clearly defined provisions for predevelopment assessments. Others such as Liberia included archaeological heritage in their environmental protection laws. Although fewer countries have had legislation to protect intangible aspects, supporting legal provisions such as national cultural policies have helped in this regard. However, very little has been done on the inclusion of customary laws and systems of archaeological protection. Going forward, African nations have to quickly consider emerging issues such as digital manipulation, heritage-based product development, increased need for intervention conservation, and sustainable economic utilization of heritage for the development of individuals, communities, and nations. The legislative process in Africa has to be expedited to quickly and efficiently deal with these issues before they cause harm to the archaeological heritage.
Stature, Poverty, and Inequality in 19th- and 20th-Century Mexico
Authors: López-Alonso Moramay
Published: December 2021

Anthropometric studies have shown that the evolution of human stature can be helpful to examine human welfare. Adult stature is an indicator of health status and living standards for periods in which there has not been a systematic collection of data of other indicators, such as the price of goods and wages, as is the case in Mexico prior to 1950. Mexican anthropometric history studies have revealed that stature is a good measure to examine the evolution of living standards in the long run and that it has been effective for assessing poverty and inequality. These studies have shown that, for the period 1850–1950, the evolution of living standards was heterogeneous. There were different trajectories depending on the socioeconomic status. People from working-class backgrounds experienced a deterioration and/or stagnation, while people from upper-class backgrounds experienced a sustained increase in average stature. These trends challenged the official history of the post-revolutionary period, which argued that the living standards of the Mexican population deteriorated during the Porfirio Díaz administration (1876–1911) and improved afterwards with the promulgation of social legislation in the post-revolutionary era (post-1910). Additional studies show that, during the post-1950 period, there was a generalized improvement in stature, but it was limited by the challenges of economic downturns and persistent structural inequality.
Liberation Theology in Latin America
Authors: Sullivan-González Douglass
Published: December 2021

Liberation theology is a critical reflection on the workings of God in the history of humankind that emphasizes the active, divine redemption (liberation) of humans from the sinful bonds of political and economic oppression. The biblical Exodus narrative became the core metaphor for the theological understanding of liberation and freedom. The Latin American bishops, during their second meeting at Medellín, Colombia, in 1968, coined a signature tenet of liberation theology: “the preferential option for the poor.”

Liberation theology emerged formally among theologians in South America in response to rising expectations produced by two key external factors: the successful Cuban revolution (1959) and the ecumenical zeitgeist associated with Vatican II (1962–1965). The movement spread quickly while increased literacy among the faithful inspired lay leaders, trained by sparse clergy and women religious, to organize Christian base communities (CEBs), to “read” their own reality in light of the Exodus story, and to campaign for social justice in alliance with secular political actors. The swift repression and assassination of clergy, nuns, and lay activists by security forces hostile to democratization of the political economy in the 1970s and early 1980s fueled international awareness of liberation theology. Heightened internal opposition within the Vatican in the 1980s to some of liberation theology’s fundamental tenets culminated with the ten-month silencing in 1985 of the Brazilian theologian and Franciscan priest Leonardo Boff. Liberation theology has since inspired other marginalized social actors to explore what liberation means for those forced to live on the periphery due to racial, ethnic, and/or gender-based discrimination; homophobia; and a rapidly deteriorating environment threatened by unsustainable development models.
Indigenous Politics and Education in Early to Mid-20th Century Chile: Foregrounding Mapuche Women and Transnational Conversations
Authors: Crow Joanna , Ramay Allison
Published: December 2021

Mapuche intellectuals and political activists in early- to mid-20th-century Chile both worked within and subverted dominant modernizing and “civilizing” educational discourses. Mapuche women played an important role in the movement to democratize schooling in early-20th-century Chile by publishing articles in little-known Mapuche-run newspapers and advocating for Mapuche education broadly as well as specifically for women. There was also an important transnational dimension of Mapuche political organizing around education rights during this period. These two underexplored but important aspects of indigenous activism in Chile open interesting questions about the intersections between race, gender, and nation in the sphere of education.
Phrase Structure and Movement in Japanese
Authors: Saito Mamoru
Published: December 2021

Japanese exhibits some unique features with respect to phrase structure and movement. It is well-known that its phrase structure is strictly head-final. It also provides ample evidence that a sentence may have more complex structure than its surface form suggests. Causative sentences are the best-known example of this. They appear to be simple sentences with verbs accompanying the causative suffix, -sase. But the causative suffix is an independent verb and takes a small clause vP complement in the syntactic representation. Japanese sentences can have a rich structure in the right periphery. For example, embedded clauses may contain up to three overt complementizers, corresponding to Finite (no), Interrogative (ka), and Report/Force (to). Matrix clauses may end in a sequence of discourse particles, such as wa, yo, and ne. Each of the complementizers and discourse particles has a selectional requirement of its own. More research is required to settle on the functional heads in the nominal structure. Among the controversial issues are whether D is present and whether Case markers should be analyzed as independent heads.

Various kinds of movement operations are observed in the language. NP-movement to the subject position takes place in passive and unaccusative sentences, and clausal comparatives and clefts are derived by operator-movement. Scrambling is a unique movement operation that should be distinguished from both NP-movement and operator-movement. It does not establish operator-variable relations but is not subject to the locality requirements imposed on NP-movement. It cannot be PF-movement as it creates new binding possibilities. It is still debated whether head movement, for example, the movement of verb to tense, takes place in the language.
New Computational Methods and the Study of the Romance Languages
Authors: Calderone Basilio , Pirrelli Vito
Published: December 2021

Nowadays, computer models of human language are instrumental to millions of people, who use them every day with little if any awareness of their existence and role. Their exponential development has had a huge impact on daily life through practical applications like machine translation or automated dialogue systems. It has also deeply affected the way we think about language as an object of scientific inquiry. Computer modeling of Romance languages has helped scholars develop new theoretical frameworks and new ways of looking at traditional approaches. In particular, computer modeling of lexical phenomena has had a profound influence on some fundamental issues in human language processing, such as the purported dichotomy between rules and exceptions, or grammar and lexicon, the inherently probabilistic nature of speakers’ perception of analogy and word internal structure, and their ability to generalize to novel items from attested evidence. Although it is probably premature to anticipate and assess the prospects of these models, their current impact on language research can hardly be overestimated. In a few years, data-driven assessment of theoretical models is expected to play an irreplaceable role in pacing progress in all branches of language sciences, from typological and pragmatic approaches to cognitive and formal ones.
Fiscal Policy in the United States
Authors: Staller Karen M.
Published: December 2021

U.S. fiscal policy is of interest to social workers as it concerns issues including structural racism, economic justice, and income inequality. U.S. fiscal policy refers to the role of the government in taxing and spending, the budget appropriations process, and public budgets (including federal and state revenue and spending). Federal revenue includes payroll and income taxes (personal and corporate). Federal outlays include discretionary and mandatory entitlement spending. There are a number of ongoing contentious debates about U.S. fiscal policy, including those involving the size and function of government, deficit financing and borrowing, inequality, and the redistribution of wealth in tax policies.
Integrating Macro–Micro Practice
Authors: Ostrander Jason A. , Kelly Kerry , Carl-Stannard Patricia
Published: December 2021

Social work sets itself apart in the “helping professions” in recognizing the significance of its students and practitioners engaging with the theoretical knowledge and practice experiences sufficient for fluency across macro to micro settings. This practice integration assures comprehensive understanding of person-in-environment, from casework to complex systems work, and is raised to an ethical standard in the National Association of Social Work Code of Ethics and in the International Federation of Social Work Principles. Yet macro-oriented scholars have accused social work educators and professionals of abandoning their obligation to social justice and policy participation and of focusing their energy instead on micro practice. This literature is helpful in addressing how integrated practice can be achieved and informs the development of social workers who solidly embrace a commitment to macro knowledge and participation.
Civil Society in Macro Social Work
Authors: Hermoso Jocelyn Clare R. , Sugawara Carmen Luca
Published: December 2021

The connection between macro social work practice and civil society is inextricable. Macro practice focuses on forming and strengthening people’s organizations, communities, and other collectivities that make up the structure and foundation of civil society, defined as the sphere outside of the state and market where people can exercise their right to participate in decision-making on political, social, and other matters that affect their lives. Working with civil society can compensate for some of the limitations of working within state institutions. Civil society’s potential and ability to serve as an arena for realizing individual and community well-being, human rights, and social justice warrant positioning it on equal footing as the state as an area of practice for the social work profession.
Arenal, Concepción
Authors: Martín-Estalayo Maribel , Castillo Aurora , Barahona María José , Leyra Begoña
Published: December 2021

This article studies the influence of Concepción Arenal (1820–1893) on the foundations of social work in Spain. With her, one can learn about the most important ideas of the 19th-century liberal school of thought, which, in its enlightened and reforming aspect, had a great impact on the consideration of human dignity, poverty, the relationship between intervener and intervened—as well as the role and responsibility of the state, civil society, and charity in social intervention. Her pragmatic perspective stands out among those authors who contributed with elements of analysis to theorizing the social question in Spain. Her singularity is defined by the centrality of the human being and the integral development of one’s abilities in a society where the necessary means can be found. Additionally, she is both a national and international inspiration thanks to her contribution to women’s rights and the reform of the penal code.
Deinstitutionalization in Macro Practice
Authors: Segal Steven P.
Published: December 2021

The deinstitutionalization policy sought to replace institutional care for populations in need of care and control with prosocial community-based alternatives. U.S. institutional populations, however, have increased since the policy’s inception by 205%. As implemented, with the assistance of advocacy and cost-cutting factions, it has succeeded only in enabling the divestiture of state responsibility for target groups. It sought to prevent unnecessary admission and retention in institutions. As implemented, deinstitutionalization initiated a process that involved a societal shift in the type of institutions and institutional alternatives used to house its target groups, often referred to as trans-institutionalization. For many in need of institutional placements, it has succeeded in preventing all admissions, expanding admissions for others. In seeking to develop community alternatives for housing, treating, and habilitating or rehabilitating its target groups, it has succeeded in establishing a variety of alternative living arrangements and showcase and model programs illustrating what can be done; yet, it has failed to deliver on investments in such programs to serve the majority of its target groups. It has resulted in the abandonment of substantial numbers to homelessness. It has been documented, from political, economic, legal, and social perspectives, how this policy has affected the care and control of populations such as older adults, children, people with mental illness or developmental disabilities, people under correctional-system supervision, and, more recently, individuals without a home. Suggestions for a truer implementation of deinstitutionalization’s initial aspirations are available.
Investigating Liriomyza (Diptera: Agromyzidae) Populations From Northeastern Brazil: mtDNA Analyses of the Global Pests L. sativae and L. huidobrensis
Authors: Sousa V R , Dias-Pini N S , Couri M S , Takiya D M
Published: December 2021

Species of Liriomyza Mik (Diptera: Agromyzidae) occur worldwide and are economically important leafminers. However, populations of some pest species, although very similar morphologically, show highly divergent mtDNA sequences, suggesting that nominal species are in fact complexes of cryptic species. This study focuses on two globally invasive pests, L. huidobrensis (Blanchard) and L. sativae Blanchard, already known to be highly destructive in Brazilian crops, although only a few studies on morphological and genetic divergences of them have been made. A total of 63 sequences of the mitochondrial cytochrome oxidase I (COI) and cytochrome oxidase II (COII) from Brazilian populations of L. huidobrensis and L. sativae collected from six crops (gypsophila, chrysanthemum, melon, watermelon, tomato, and onion) in Northeastern Brazil were generated to investigate their genetic structure together with available sequences from the Americas, Europe, Asia, Africa, and Australia. Genetic structure was not found to be correlated to neither host plant nor geographical locality. Liriomyza huidobrensis showed an overall low intraspecific global genetic divergence in both genes. On the other hand, high intraspecific divergences for L. sativae and its phylogenetic position confirm a divergent clade currently found only in Brazil and suggest it may be a global complex of cryptic species. Considering the possibility of cryptic species (in the latter case), we provided detailed redescriptions of these Brazilian populations for future studies and local management of these global pests. Finally, our results also revealed a new synonym herein proposed, L. strigosa Spencer as a junior synonym of L. huidobrensis.
History Can Be Open Source: Democratic Dreams and the Rise of Digital History
Authors: Locke Joseph L. , Wright Ben
Published: December 2021

In an ongoing commitment to experimentation, the AHR invited an “open peer review” of a submitted manuscript, “History Can Be Open Source: Democratic Dreams and the Rise of Digital History,” by Joseph L. Locke (University of Houston–Victoria) and Ben Wright (University of Texas at Dallas). Given that Locke and Wright argued for the coexistence of transparency alongside formal academic peer review, subjecting their submission to an open review made sense. The peer review process itself tested the propositions about the democratization of scholarship they put forth in their submission. Their article appears in a new section of the AHR, “Writing History in a Digital Age,” overseen by consulting editor Lara Putnam (https://ahropenreview.com/). The maturation of digital history has propelled historians’ embrace of open educational resources. But, this article argues, open access licensing is not enough. Digital history’s earliest practitioners promised not just more accessible digital materials, but a broader democratization of history itself. This article therefore moves beyond questions of technological innovation and digital access in the rise of digital history to engage more fundamental and intractable questions about inequality, community, and participatory historical inquiry.
Vec2image: an explainable artificial intelligence model for the feature representation and classification of high-dimensional biological data by vector-to-image conversion
Authors: Tang Hui , Yu Xiangtian , Liu Rui , Zeng Tao
Published: December 2021

Feature representation and discriminative learning are proven models and technologies in artificial intelligence fields; however, major challenges for machine learning on large biological datasets are learning an effective model with mechanistical explanation on the model determination and prediction. To satisfy such demands, we developed Vec2image, an explainable convolutional neural network framework for characterizing the feature engineering, feature selection and classifier training that is mainly based on the collaboration of principal component coordinate conversion, deep residual neural networks and embedded k-nearest neighbor representation on pseudo images of high-dimensional biological data, where the pseudo images represent feature measurements and feature associations simultaneously. Vec2image has achieved better performance compared with other popular methods and illustrated its efficiency on feature selection in cell marker identification from tissue-specific single-cell datasets. In particular, in a case study on type 2 diabetes (T2D) by multiple human islet scRNA-seq datasets, Vec2image first displayed robust performance on T2D classification model building across different datasets, then a specific Vec2image model was trained to accurately recognize the cell state and efficiently rank feature genes relevant to T2D which uncovered potential T2D cellular pathogenesis; and next the cell activity changes, cell composition imbalances and cell–cell communication dysfunctions were associated to our finding T2D feature genes from both population-shared and individual-specific perspectives. Collectively, Vec2image is a new and efficient explainable artificial intelligence methodology that can be widely applied in human-readable classification and prediction on the basis of pseudo image representation of biological deep sequencing data.
Caviar-Sunflower Optimization Algorithm-Based Deep Learning Classifier for Multi-Document Summarization
Authors: J Sheela , B Janet
Published: December 2021

This paper proposes a multi-document summarization model using an optimization algorithm named CAVIAR Sun Flower Optimization (CAV-SFO). In this method, two classifiers, namely: Generative Adversarial Network (GAN) classifier and Deep Recurrent Neural Network (Deep RNN), are utilized to generate a score for summarizing multi-documents. Initially, the simHash method is applied for removing the duplicate/real duplicate contents from sentences. Then, the result is given to the proposed CAV-SFO based GAN classifier to determine the score for individual sentences. The CAV-SFO is newly designed by incorporating CAVIAR with Sun Flower Optimization Algorithm (SFO). On the other hand, the pre-processing step is done for duplicate-removed sentences from input multi-document based on stop word removal and stemming. Afterward, text-based features are extracted from pre-processed documents, and then CAV-SFO based Deep RNN is introduced for generating a score; thereby, the internal model parameters are optimally tuned. Finally, the score generated by CAV-SFO based GAN and CAV-SFO based Deep RNN is hybridized, and the final score is obtained using a multi-document compression ratio. The proposed TaylorALO-based GAN showed improved results with maximal precision of 0.989, maximal recall of 0.986, maximal F-Measure of 0.823, maximal Rouge-Precision of 0.930, and maximal Rouge-recall of 0.870.
The impact of diabetes on short-, intermediate- and long-term mortality following left ventricular assist device implantation
Authors: Kogan Alexander , Frogel Jonathan , Ram Eilon , Jamal Tamer , Peled-Potashnik Yael , Maor Elad , Grupper Avishay , Morgan Avi , Segev Amit , Raanani Ehud , Sternik Leonid
Published: December 2021

OBJECTIVES

Type 2 diabetes mellitus (DM) is a frequent comorbidity among patients suffering from advanced heart failure necessitating a left ventricular assist device (LVAD) implant. The goal of this study was to evaluate the impact of type 2 DM on early and long-term outcomes of patients following an LVAD implant.

METHODS

We performed an observational cohort study in a large tertiary care centre in Israel. All data of patients who underwent a continuous flow LVAD implant between 2006 and 2020 were extracted from our departmental database. Patients were divided into 2 groups: group I (patients without diabetes) and group II (patients with diabetes). We compared short-term (30-day and 3-month) mortality, intermediate-term (1- and 3-year) mortality and long-term (5 year) mortality between the 2 groups.

RESULTS

The study population included 154 patients. Group I (patients without diabetes) comprised 88 patients and group II (patients with diabetes) comprised 66 patients. The mean follow-up duration was 38.2 ± 30.3 months. Short- and intermediate-term mortality (30 days, 1 year and 3 years) was higher in the group with DM compared with the group without DM but did not reach any statistically significant difference: 16.1% vs 9.8% (P = 0.312), 24.2% vs 17.3% (P = 0.399) and 30.6% vs 21.9% (P = 0.127) respectively. Long-term 5-year mortality was significantly higher in the group with DM compared to the group without: 38.7% vs 24.4% (P = 0.038). Furthermore, predictors of long-term mortality included diabetes (hazard ratio 2.09, confidence interval 1.34–2.84, P = 0.004), as demonstrated by regression analysis.

CONCLUSIONS

Patients with diabetes and those without diabetes have similar 30-day and short- and intermediate-term mortality rates. The mortality risk of diabetic patients begins to increase 3 years after an LVAD implant. Diabetes is an independent predictor of long-term, 5-year mortality after an LVAD implant.

Clinical trial registration

Ethical Committee of Sheba Medical Centre, Israel, on 2 December 2014, Protocol 4257.
Spatial and Temporal Patterns in Carbon and Nitrogen Inputs by Net Precipitation in Atlantic Forest, Brazil
Authors: Mantovani Vanessa Alves , Terra Marcela de Castro Nunes Santos , de Mello Carlos Rogério , Rodrigues André Ferreira , de Oliveira Vinicius Augusto , Pinto Luiz Otávio Rodrigues
Published: December 2021

Understanding both carbon and nitrogen temporal and spatial inputs by rainfall in tropical forests is critical for proper forest conservation and management and might ultimately elucidate how climate change might affect nutrient dynamics in forest ecosystems. This study aimed to quantify the net precipitation contribution to the Atlantic Forest’s total carbon (C) and total nitrogen (N), identifying potential differences between these inputs regarding temporal (seasonal and monthly) and spatial scales. Rainfall samples were collected before and after interacting with the forest canopy from May 2018 to April 2019. The rainfall was enriched after crossing the forest canopy. Significant differences were found for gross rainfall and net precipitation between annual carbon (104.13 kg ha−1 and 193.18 kg ha−1) and nitrogen (16.81 kg ha−1 and 36.95 kg ha−1) inputs, respectively. Moreover, there was seasonal variability in the C and N inputs with 75% occurring in the wet season. Overall, the spatial patterns revealed that the same locations had the highest inputs regardless of the analyzed period. The forest-rainfall interactions provide constant C and N inputs, especially in the wet season, and are fundamental for the maintenance of ecological processes.
RNA sequencing-based screen for reactivation of silenced alleles of autosomal genes
Authors: Gupta Saumya , Lafontaine Denis L , Vigneau Sebastien , Mendelevich Asia , Vinogradova Svetlana , Igarashi Kyomi J , Bortvin Andrew , Alves-Pereira Clara F , Nag Anwesha , Gimelbrant Alexander A
Published: December 2021

In mammalian cells, maternal and paternal alleles usually have similar transcriptional activity. Epigenetic mechanisms such as X-chromosome inactivation (XCI) and imprinting were historically viewed as rare exceptions to this rule. Discovery of autosomal monoallelic autosomal expression (MAE) a decade ago revealed an additional allele-specific mode regulating thousands of mammalian genes. Despite MAE prevalence, its mechanistic basis remains unknown. Using an RNA sequencing-based screen for reactivation of silenced alleles, we identified DNA methylation as key mechanism of MAE mitotic maintenance. In contrast with the all-or-nothing allelic choice in XCI, allele-specific expression in MAE loci is tunable, with exact allelic imbalance dependent on the extent of DNA methylation. In a subset of MAE genes, allelic imbalance was insensitive to DNA demethylation, implicating additional mechanisms in MAE maintenance in these loci. Our findings identify a key mechanism of MAE maintenance and provide basis for understanding the biological role of MAE.
Evolution of the canonical sex chromosomes of the guppy and its relatives
Authors: Kirkpatrick Mark , Sardell Jason M , Pinto Brendan J , Dixon Groves , Peichel Catherine L , Schartl Manfred
Published: December 2021

The sex chromosomes of the guppy, Poecilia reticulata, and its close relatives are of particular interest: they are much younger than the highly degenerate sex chromosomes of model systems such as humans and Drosophila melanogaster, and they carry many of the genes responsible for the males’ dramatic coloration. Over the last decade, several studies have analyzed these sex chromosomes using a variety of approaches including sequencing genomes and transcriptomes, cytology, and linkage mapping. Conflicting conclusions have emerged, in particular concerning the history of the sex chromosomes and the evolution of suppressed recombination between the X and Y. Here, we address these controversies by reviewing the evidence and reanalyzing data. We find no evidence of a nonrecombining sex-determining region or evolutionary strata in P. reticulata. Furthermore, we find that the data most strongly support the hypothesis that the sex-determining regions of 2 close relatives of the guppy, Poecilia wingei and Micropoecilia picta, evolved independently after their lineages diverged. We identify possible causes of conflicting results in previous studies and suggest best practices going forward.
Stability-Indicating Analytical Method Development Using Quality by Design (QbD) Approach for Simultaneous Estimation of Budesonide and Levosalbutamol
Authors: Gandhi Noopur , Ezhava Sindhu
Published: December 2021

Background

Budesonide is a corticosteroid; levosalbutamol is bronchodilator. In combination, they are used in the treatment of asthma and chronic obstructive pulmonary disease.

Objective

The present article portrays the development of a stability-indicating high-performance thin-layer chromatography (HPTLC) method for the simultaneous estimation of budesonide and levosalbutamol using design of experiment (DOE) principles.

Method

DOE was applied in development part in which a Box-Behnken design was used to study the effect of factors on the Rf value of the drugs. Twenty-five experimental runs were performed to optimize the chromatographic conditions. Aluminum sheets precoated with silica gel 60 F254 were used as the stationary phase. The optimized mobile phase composition was found to be toluene–ethyl acetate–methanol–ammonia (4:1.8:1.8:0.2) and saturation time 20 min, quantified by densitometric analysis at 231 nm. Moreover, the drugs were subjected to acid and alkali hydrolysis, oxidation, thermal, and photodegradation.

Results

The drugs undergo degradation under mainly acidic and basic conditions. Also, the degraded products were well resolved from the pure drug with significantly different Rf values. Linearity was performed in the ranges of 224–1120 ng/band for budesonide and 280–1400 ng/band for levosalbutamol. The method was validated according to the International Conference on Harmonization guidelines.

Conclusions

This approach is useful to expedite method development and optimization activities in analytical laboratories.

Highlights

The experimental data revealed that the volume of toluene and methanol in the mobile phase significantly affected the Rf value of both the drugs, and ammonia significantly affected the Rf value of levosalbutamol.
Understanding Out-Mobility and Radical-Right Support as Responses to Differentiated Refugee Exposure
Authors: de la Prada Àlex G
Published: December 2021

The refugee crisis of 2015 became a major issue of both national and pan-European debate. Behavioral reactions among natives in the form of support for radical-right parties or leaving neighborhoods following influxes of non-Westerners are well documented, but a detailed account of how asylum seekers contribute to these dynamics remains elusive. In this paper, I study how asylum centers and refugees choosing their own residences prompt each of these two behavioral outcomes using register data for the whole of Sweden (2013–2018). The analyses show a divergence depending on the particular type of refugee exposure experienced and the specific behavior under analysis. Only increased radical-right support is observed following the establishment of a new asylum center, whereas greater native out-mobility is found following refugees self-selecting into native-based areas.
Chylomicronemia Due to the Rare Hyperlipoproteinemia Type 3 Complicated by a Circulating Monoclonal Protein
Authors: Basheer Hiba , Nakhaee Beheshteh , Jialal Ishwarlal
Published: December 2021

The polygenic variety of chylomicronemia occurs in adults in whom factors such as obesity, diabetes, alcoholism, renal disease, and certain drugs can precipitate chylomicronemia. A rare cause of polygenic chylomicronemia is hyperlipoproteinemia type 3 (HLP3). We report on a 54-year-old male who presented with chylomicronemia with triglycerides (TG) >2000 mg/dL. From admission, the ratio of total cholesterol to total triglycerides was not below 0.2 but was closer to 0.5, suggesting that his condition was not classic chylomicronemia. We confirmed that the patient had HLP3 based on his very-low-density lipoprotein cholesterol (VLDL-C)/TG ratio, which was ≥0.3, and lipoprotein electrophoresis showing a broad beta band. Because he was not responsive to initial therapy, we considered an interferent impairing lipolysis and TG reduction. The interferent was an M-protein that may also have falsely elevated both apolipoprotein-B and direct-LDL-C levels. In this case study, we report on a patient with chylomicronemia resulting from HLP3 complicated by a circulating M-protein.
3D spatio-kinematic modelling of Abell 48, a planetary nebula around a Wolf–Rayet [WN] star
Authors: Danehkar A
Published: December 2021

The planetary nebula (PN) Abell 48 (PN G029.0+00.4) is around a rare Wolf–Rayet [WN5] star whose stellar history is as yet unknown. Using the integral field observations of the H αλ6563 and [N ii] λ6584 line emissions, we conducted a comprehensive spatio-kinematic analysis of this PN. A three-dimensional spatio-kinematic ionization model was developed with the kinematic modelling tool shape to replicate the observed spatially resolved velocity channels and position–velocity diagrams. According to our kinematic analysis of the H α emission, this object possesses a deformed elliptic toroidal shell with an outer radius of 23 arcsec and a thickness of 15 arcsec associated with an integrated H α emission-line expansion of ∼35 ± 5 km s−1, a maximum poloidal expansion of around 70 ± 20 km s−1 at an inclination angle of ∼30° with respect to the line of sight, and a position angle of ∼130° measured from east towards north in the equatorial coordinate system. Furthermore, [N ii] kinematic modelling reveals the presence of narrow (∼3 arcsec) exterior low-ionization structures surrounding the main elliptical shell, which could have formed as a result of shock collisions with the interstellar medium. The torus-shaped morphology of this PN could be related to its unusual hydrogen-deficient [WN] nucleus that needs to be inspected further.