bluuebunny/crossref_metadata_2025 huggingface dataset:
Caracterización de la roca soporte de los petroglifos de Campo Lameiro (Pontevedra)
Authors: Silva Benita , Sanmartín Patricia , Prieto Beatriz
Published: April 2021

Entre los años 2005-2008 se llevó a cabo un proyecto de investigación para analizar las causas del deterioro de los petroglifos de Campo Lameiro (Pontevedra). La roca soporte de los grabados se caracterizó como un granito de dos micas de grano medio-fino y textura granuda equigranular alotriomorfa. Presenta una intensa fisuración a todos los niveles lo que le confiere una elevada porosidad y gran capacidad de absorción de agua. En campo se observa una densa red de diaclasas, sin embargo un estudio específico reveló que esto no supone riesgo de pérdida masiva de roca que pueda afectar a las superficies que poseen grabados. Los análisis mineralógicos y geoquímicos pusieron de manifiesto que el granito experimentó procesos de hidrólisis y de solubilización-precipitación del hierro, lo que indica que es el agua el principal agente de alteración en el material lítico.
Non-destructive studies of prehistoric lithic material culture in the search for sources of geologic raw materials: an overview of techniques and issues
Authors: Xavier Pedro , Alves Carlos
Published: April 2021

Geological raw materials are an important component of the archaeological record in the Prehistory (namely due to their persistence under buried conditions) and pinpointing their original position on the geological context could give important information about activities of ancient human groups. However, archaeological lithic artefacts impose strict restrictions on analytical procedures due to the need to preserve features with cultural meaning, which might affect the effectiveness of the analytical procedure. We attempt here a critical overview of non-destructive techniques for the search of the source of geological raw materials used to make prehistoric lithic artefacts, highlighting issues involved in the interactions between techniques and study objects. It is emphasized that the success of provenance studies will strongly depend on the sensitivity of the analyses undertaken to the characteristics of the sample, as well as the geological information available.
Online Game Addiction and Gen Z: A Comparative Study on Turkish and Romanian High School Students
Authors: KARCI Huri Deniz , URHAN Bahar
Published: April 2021

As being among “the digital natives” of the technology era, Generation Z and their online behaviors are important subjects to study in depth. Surrounded by technology, Generation Z is easily getting and using all technology products, and they do not feel any constraint about spending time with them, which might lead to a kind of addiction. The study was designed to examine the two-factor solution of online gaming addiction by Faraci and her colleagues’ internet addiction version employing the IAT of 20 items by Young. In order to reveal the present state, two field studies in two high schools from Turkey and Romania were run comparatively. Turkish and Romanian participants replied the 20-item-IAT and the questionnaire about online gaming behavior via an online survey platform. To determine the dimensions of online gaming addiction exploratory factor analysis and confirmatory factor analysis are performed. Reliability coefficients of both factors were satisfactory. According to confirmatory factor analysis goodness-of-fit indexes in both samples were reasonable. In conclusion, both factors fit well into the present study producing some other results about online gaming behavior, as well.
Olağandışı Süreçlerde Kamu Diplomasisi: Covid-19 Pandemisi ve Türkiye'nin Kamu Diplomasisi Faaliyetleri
Authors: KOYUNCU Serhan
Published: April 2021

Covid-19 pandemisi, 2019 yılı aralık ayında dünyada ilk kez görülmüştür. Pandemi birkaç ay içerisinde tüm dünyaya yayılmıştır. Pandeminin tüm dünyayı etkisi altına alması uluslararası alanda işbirliği yapılmasını zorunlu kılmış, pandeminin ortadan kaldırılması için ortak politikalar üretilmiş, farklı ülkelerin katılımıyla aşı çalışmaları başlatılmıştır. Kamu diplomasisi olağan süreçlerde olduğu gibi pandemi gibi olağandışı süreçlerde de önemli bir araçtır. Olağan zamanlarda proaktif kamu diplomasisi öne çıkarken, olağandışı zamanlarda reaktif kamu diplomasisi anlayışı benimsenmektedir. Bu çalışmada da Türkiye’nin pandemi sürecindeki kamu diplomasisi pratikleri analiz edilmiştir. Çalışmanın problemi; olağandışı süreçlerde etkin kamu diplomasisi pratiklerinin nasıl işlerlik kazandığıdır. Çalışma ile Türkiye’nin pandemi sürecindeki kamu diplomasisi faaliyetlerinin irdelenerek bu doğrultuda yeni medyanın nasıl bir işlev gördüğünün ortaya çıkarılması amaçlanmıştır. Çalışma pandemi gibi güncel bir konu temelinde kamu diplomasisine odaklanarak literatüre katkı yapması bakımından önem taşımaktadır. Çalışmada veri toplama tekniği olarak içerik/veri taraması tekniği, analiz yöntemi olarak ise betimsel analiz yöntemi benimsenmiştir. Çalışmada Türkiye’nin kamu diplomasisi faaliyetleri “Çin’den tahliye” ve “tıbbî yardım” konu başlıkları altında analiz edilerek Twitter üzerinden somut örneklere ulaşılmış ve bunlar değerlendirilmiştir.
COVID-19 Haberlerinde Siyasi Kutuplaşmanın Yansımaları: Hürriyet ve Gazete Pencere Üzerine Bir İnceleme
Authors: ŞİRVANLI Turancan
Published: April 2021

Bu çalışmada, Türkiye’yi etkisi altına alan COVID-19 pandemi sürecinin alternatif ve ana akım basında, siyasi kutuplaşma kavramından hareketle ne ölçüde ve nasıl sunulduğunun araştırılması amaçlanmıştır. COVID-19 pandemisi halk sağlığını ilgilendiren bir mesele olduğu için, sürece ilişkin üretilen haber metinlerinin gazetelerin siyasi yönelimlerinden bağımsız olması beklenmektedir. Bu bağlamda, çalışmada araştırma nesnesi olarak ideolojik yönelimi görece “merkez medya” konumundaki iki gazete seçilmiştir. Ekonomi politik anlamda ana akım ve alternatif medya olarak tanımlanabilecek iki farklı gazete olan Hürriyet ve Gazete Pencere, nicel ve nitel analiz yöntemleri kullanılarak incelenmiştir. Araştırma sonuçlarına göre, Gazete Pencere, COVID-19’a ilişkin haberleri daha çok “Vaka ve ölüm sayılarının doğru verilmemesi” ve “Devlet yetkililerinin kısıtlamalara uymaması” konuları üzerinden çerçevelerken, Hürriyet gazetesi COVID-19 haberlerini, “yurttaşların tedbirlere uymaması” ekseninde yansıtmaktadır. Bu durum, Türkiye’deki iktidar ve muhalefet kanadındaki aktörlerin argümanları ile uyumluluk taşımaktadır. Aynı zamanda iki gazetede de politikacıların bilim insanlarından daha sık yer aldığı görülmektedir. Çalışmada, kutuplaşmış politik ve toplumsal alandaki güç ve iktidar mücadelesinin -sağlık konusu ön planda olmasına ve gazetelerin görece merkez medya konumlarına rağmen- medya alanında da kendisini gösterdiği sonucuna ulaşılmıştır.
Abbas Kiarostami Filmlerinde Gerçekçilik: Yakın Çekim (Nema-ye Nazdik – 1990) Filminin Nokta Metaforuyla Yeni Bir Okuması
Authors: ŞAHİN Murat
Published: April 2021

Bu çalışmada, Abbas Kiarostami’nin yönetmenliğini yaptığı Yakın Çekim (1990) filminin, sinema ve gerçekçilik bağlamında analizi yapılmıştır. Analiz yapılırken nokta metaforundan yararlanılmıştır. Nokta metaforu, gerçeğin bir nüvesi, gerçekliğe ulaşma çabasının bir izdüşümü ve kendinden hareketle gerçeğin çoğaltılması bakımından önem taşımaktadır. Bu bakımdan nokta metaforunun sağladığı anlam zenginliğinden yararlanılarak filmin sinematografik ögeleri olan yakın çekim kullanımı, senografik ögelerin tercihi ve ses kullanımı gibi unsurlar üzerinden analizi yapılmıştır. Yakın Çekim filminde yönetmen Abbas Kiarostami, nokta olan bir gerçeğin peşine düşmektedir. Kiarostami, bu gerçeğin üzerini örten perdelerin aralanmasını istemektedir. Gerçekçi film kuramcıları, gerçeğin çok boyutlu olduğunu ve ortaya çıkarılmasının gerektiğini ifade ederler. Filmde gerçeğin ortaya çıkarılması için yakın çekim, diyalog, ses ve çeşitli senografik unsurlardan yararlanılmıştır. Filmde nokta metaforunun bir uzantısı olarak gerçeğe ulaşma adına yakın plan çekim yönteminin sıklıkla kullanıldığı görülmüştür. Kurmaca ve gerçek arasındaki ince sınırda ilerleyen filmde, gerçeklik yanılsaması da yer almaktadır. Ses unsuru da yine gerçekliği tamamlayan bir öge olarak kullanılmıştır. Son olarak senografik ögelerin nokta metaforuyla bir arada düşünüldüğünde gerçeğe ulaşma adına işlevsel bir rolü olduğu görülmüştür.
Adipose Derived Mesenchymal Stem Cells Restore Spermatogenesis in Male non Obstructive Azoospermia (Literature Review)
Authors: Tamadon A. , Askarov M.B. , Zhanbyrbekuly U. , Zhankina R.A. , Saipiyeva D.T. , Ibragimov A.K. , Kadirova B.E. , Yessenuly A. , Sherkhanov R.S. , Suleiman M.A.
Published: April 2021

Stem cells are considered as new much promising therapeutic agents in treatment of male infertility due to their high differentiation potential and unlimited supply. In this review we summarized current views on application of mesenchymal stem cells in reproductive medicine.
Gut Microbiome and Drug Metabolism
Authors: Ilina E.N. , Mayorova E.M. , Manolov A.I. , Korenkova A.A. , Bahmetjev V.V. , Gorbunov K.S.
Published: April 2021

The human physiology textbooks traditionally consider the intestine as a metabolically active organ, with its activity primarily associated with the production of numerous digestive enzymes. The development of molecular analysis technologies has significantly detailized this picture, primarily by decoding the metabolic potential of the intestinal microbiota. Data from numerous metagenomic studies indicate that the number of eukaryotic and bacterial cells in the human body is comparable - about 3.0×1013, while the number of genes in the intestinal metagenome is one hundred times greater than in the human genome. Obviously, the gut microbiota exhibits both direct and indirect effects on the metabolism of drugs and xenobiotics, that can affect their effectiveness and toxicity. Orally administrated xenobiotics have been found to be metabolized by intestinal microbial enzymes before being absorbed from the gastrointestinal tract into the blood flow. The metabolic reactions performed by the gut microbiota greatly differ from the metabolic reactions of the liver, providing modification of drugs by acetylation, deacetylation, decarboxylation, dehydroxylation, demethylation, dehalogenation, etc. Despite the metabolism of xenobiotics by microbial enzymes of the intestine is rather known, information about the specific microflora mediating each metabolic reaction is still limited, mainly by the lack of an adequate model of the intestinal microbial community to allow the accumulation of experimental data for the creation of computational models. Currently, studies of drug metabolism use microfluidic chips, reproducing functions of various organs and tissues, such as the liver, kidney, lungs and intestine, as in vitro models in the form of 2D and 3D cell cultures. Supplementation of such systems with the microbial community will allow to get as close as possible to in vitro modeling of complicated biological processes in the interests of pharmacological research and the accumulation of data for constructing computational models.
The gene expression signature in endothelial cells exposed to mitomycin C
Authors: Sinitsky M.Yu. , Tsepokina A.V. , Kutikhin A.G. , Shishkova D.K. , Ponasenko A.V.
Published: April 2021

The expression of DNA repair (DDB1, ERCC4, ERCC5), leukocyte adhesion (VCAM1, ICAM1, SELE, SELP), endothelial mechanotransduction (KLF4), endothelial differentiation (PECAM1, CDH5, CD34, NOS3), endothelial-to-mesenchymal transition (SNAI1, SNAI2, TWIST1, GATA4, ZEB1, CDH2), scavenger receptors (LOX1, SCARF1, CD36, LDLR, VLDR), antioxidant system (PXDN, CAT, SOD1) and transcription factor (HEY2) genes in primary human coronary (HCAEC) and internal thoracic (HITAEC) arteries endothelial cells exposed to alkylating mutagen mitomycin C (MMC) was studied at two time points — after 6 h of incubation with MMC and after 6 h of the genotoxic load followed by 24 h of incubation in pure culture medium using the quantitative PCR. Immediately after MMC exposure, in the exposed HCAEC and HITAEC a decreased expression of almost all studied genes was noted excepted SNAI, which demonstrated a 4-told increase in its expression compared to the unexposed control. Elimination of MMC from the cultures, an increased expression of the VCAM1, ICAM1, SELE, SNAI2, KLF4 genes and a decreased the mRNA level of the PECAM1, CDH5, CD34, ZEB1, CAT, PXDN genes were observed in both cell lines. In addition, HITAEC cells were characterized by a decreased expression of the SOD1, SCARF1, CD36 genes and an increased expression of the SNAI1 and TWIST1 genes; in HCAEC, an increased mRNA level of the LDLR and VLDLR genes was noted. Thus, MMC-induced genotoxic stress is associated with the endothelial dysfunction.
Effect of sliding discharge on proliferation and death of brain microvessel endothelial cells in vitro
Authors: Muradyan G.A. , Gudkova E.S. , Khilazheva E.D. , Morgun A.V. , Malinovskaya N.A. , Salmina A.B. , Salmin V.V.
Published: April 2021

The dose-dependent effects of plasma exposure to a unipolar nanosecond sliding discharge over the surface of the culture medium in a closed plate on the cells of cerebral endothelium in vitro were studied. Using a 24-well plate, the surface plasma energy density of one pulse was 360 μJ/cm2 at a pulse frequency of 100 Hz. It has been shown that in the creeping discharge plasma there is an active excitation of air molecules, the formation of positive nitrogen and oxygen ions, and the formation of carbon monoxide. In the dose density range of 0-32 J/cm2, the dose-dependent effects were assessed in the 4-12 h post-radiation period. Cell death was analyzed with an assessment of the total number of cells, necrotic cells, cells in apoptosis (phosphatidylserine externalization, internucleosomal DNA fragmentation) and their proliferative activity (Ki67-immunopositive cells). A preliminary assessment of subtle dose-dependent effects indicates the peculiarities of the effect of small doses
Possible mechanism of antioxidant action of dinitrosyl iron complexes
Authors: Shumaev K.B. , Kosmachevskaya O.V. , Grachev D.I. , Timoshin A.A. , Topunov A.F. , Lankin V.Z. , Ruuge E.K.
Published: April 2021

The antioxidant effect of dinitrosyl iron complexes (DNICs) was studied in various model systems. DNICs with glutathione ligands effectively inhibited Cu2+-induced peroxidation of low density lipoproteins (LDL). The antioxidant effect of DNICs with phosphate ligands and free reduced glutathione (GSH) was less pronounced. In addition, DNICs with glutathione suppressed the formation of reactive oxygen species during co-oxidation of lecithin liposomes and glucose. Free radical oxidation in this system was induced with a lipophilic azo initiator and evaluated by luminol-dependent chemiluminescence. NO sharply stimulated chemiluminescence during co-oxidation of glucose and liposomes, thus suggesting the formation of potent oxidants under these conditions. Glutathione DNICs scavenge the superoxide radical anion generated in the xanthine-xanthine oxidase system. Superoxide production was assessed by lucigenin-dependent chemiluminescence and electron paramagnetic resonance (EPR) spectroscopy. Chemiluminescence revealed the dose-dependent character of antiradical effect of glutathione DNICs; moreover, these complexes turned out to be more efficient than GSH. EPR spectra of the adducts of the DEPMPO spin trap with free radicals suggest that the interaction of glutathione DNICs and superoxide does not result in the formation of the thiyl radical of glutathione. Here we propose a mechanism of the antioxidant action of glutathione DNICs, suggesting that unstable intermediate complexes are formed upon their interaction with superoxide or lipid radicals. Further, as a result of intramolecular rearrangement, these intermediates decompose without the free radical as the by-products.
Stony Mountain Institution
Authors: Beaulieu William Allan
Published: April 2021

Contribution to the dialogue on Canada’s federal penitentiary system and the need for penal reform.
Saskatchewan Penitentiary
Authors: Anonymous Prisoner 15 *
Published: April 2021

Contribution to the dialogue on Canada’s federal penitentiary system and the need for penal reform.
Saskatchewan Penitentiary
Authors: Anonymous Prisoner 16 *
Published: April 2021

Contribution to the dialogue on Canada’s federal penitentiary system and the need for penal reform.
Drumheller Institution
Authors: Anonymous Prisoner 19 *
Published: April 2021

Contribution to the dialogue on Canada’s federal penitentiary system and the need for penal reform.
Mission Institution
Authors: J.D. *
Published: April 2021

Contribution to the dialogue on Canada’s federal penitentiary system and the need for penal reform.
Mission Institution
Authors: P.R. *
Published: April 2021

Contribution to the dialogue on Canada’s federal penitentiary system and the need for penal reform.
More Stormy Weather or Sunny Ways? A Forecast for Change by Prisoners of the Canadian Carceral State
Authors: Shook Jarrod , McInnis Bridget
Published: April 2021

Upon being elected, Prime Minister Justin Trudeau (2015) mandated the Minister of Justice and Attorney General of Canada Jody Wilson Raybould to review criminal justice laws, policies and practices enacted during the 2006-2015 period where successive Conservative federal governments were in power. Recognizing that the knowledge produced by prisoners, particularly when brought together with academic arguments, can serve to enlighten public discourse about the current state of carceral institutions, the Journal of Prisoners on Prisons undertook a Canada-wide consultation with federal prisoners with regard to what changes have occurred in the institutions where they have served time in the last decade. This paper, which summarizes that consultation, begins with an overview of the Conservative punishment agenda, followed with a thematic review of how these changes have affected prisoners and what they would like to see moving forward in the context of the governments promised review of the Canadian criminal justice system. Representing the captive from every region of the country at all security levels and privileging the voices of Women, Black, Indigenous, LGBTQ, and Elderly prisoners, the ten most prevalent areas of concern and reform that emerged include: sentencing, mental health, health care, food, prisoner pay, old age security, education and vocational training, case management and staff culture, parole and conditional release conditions, and pardons.
A study on prevalence of various mood disorders in patients with multiple sclerosis in South Indian population Chennai, Tamil Nadu
Authors: Murugaiyan Sivaji , Sivaji Akshaya Rathin , Vijay A. Marian Jude , Sundaramurthi Indumathi , Marimuthu Jawahar
Published: April 2021

Background: The prevalence of depressive disorders are more common in demyelination diseases like multiple sclerosis. Patients with multiple sclerosis have higher rates of depressive episodes than the general population. It is found that 40-50% incidence reported in many number of previous research studies .The aim is to study the prevalence of various depressive disorders in multiple sclerosis (MS) patient population.Methods: 176 MS patients were randomly selected from neurology outpatient department (OPD) of Tamil Nadu Government Multi Super Specialty Hospital and Rajiv Gandhi Government General Hospital, Chennai, Tamil Nadu, from September 2018 to December 2019. 128 patients were analyzed with the following methods of examinations such as the structured psychiatric clinical interview with diagnostic and statistical manual of mental disorders (DSM)-5 and international classification of diseases (ICD)-10 criteria, Hamilton depression rating scale (HAM-D) scale.Results: Various subtypes of mood disorders were found as follows major depressive disorder (MDD)-4%, MDD with anxiety-6%, pervasive developmental disorders (PDD) mixed-4%, premenstrual dysphoric disorder (PMDD)-8%, MIDD-2% and depressive disorders due to general medical conditions (secondary depression)-22%. In this present study 46% of the MS population were diagnosed with various depressive illness.Conclusions: Early identification and treatment of depressive disorders definitely favour the outcome of MS patients. The coping skills and good social support system play a vital role in the outcome of depressive disorders in MS population in addition to psychopharmacological management.
Comparative study of management of intertrochanteric fracture by dynamic hip screw and proximal femoral nailing
Authors: Parsurampuriya Vivek Kumar , Siddiqui M. Shahbaz , Kumar Ritesh , Jacob Rejo Varghese
Published: April 2021

Background: The purpose of the present study is to verify the theoretical advantages of the intramedullary device over the dynamic hip screw devices and also whether it actually alters the eventual functional outcome of the patient.          

Methods: The study is comparative prospective study in which 40 patients were taken and treated either with dynamic hip screw or proximal femoral nailing. The clinical data will be collected and compared with pre-injury activity and present functional level with modified Harris hip score.

Results: We found that there is no significant difference between Harris hip score in stable fracture (p value=0.222) fixed either with DHS or PFN. But there is statistically significant difference of score in unstable fracture (p value 0.040) treated by DHS and PFN. Functionally, utilizing the Harris hip scoring system, at the final follow-up, our study affirms PFN to be superior to DHS in unstable intertrochanteric fractures while in stable fractures, functional results are same.                                                                                         

Conclusions: PFN is also found better in unstable fractures, because a greater number of patients having excellent Harris hip score. In stable fracture, functional result is same in both groups.
Apr``es la pandémie : Transformations des villes, du travail, et la crise climatique
Authors: Mirza Vincent
Published: April 2021

Cet article vise à discuter dans le contexte de la pandémie la relation entre la crise climatique, les transformations du travail et la réorganisation des villes à partir de l’idée que la pandémie est une résultante de la crise climatique dont la sortie ne peut pas être envisagée sans reconfigurer les espaces urbains et repenser les inégalités afin de penser différentes formes sociales qui concilient des villes vertes, saines et plus égalitaires.
Investigating the Service Quality of Kocaeli Tram Service Using Artificial Neural Networks
Authors: DÜNDAR Selim
Published: April 2021

Service quality is one of the main issues that today's world. Firms operating in the transportation sector are also trying to improve the quality of the service they provide to their passengers. It is crucial to determine the passengers' service quality perceptions and priorities to evaluate and improve the service in this context. In this study, Kocaeli's tram service users' service quality perceptions have been evaluated by applying a survey consisting of 20 questions and user satisfaction levels from different service dimensions. Later, an artificial neural network model was developed using the users' demographic data and their responses to the survey questions to mimic their service quality satisfaction. The artificial neural network model developed has been examined to understand the importance that tram users give to service quality. Using the developed the “change of score” method, how the changes to be made in the tram system will affect the quality of service and how the opinions of different user groups will be affected can be examined in detail. The artificial neural network model's prediction capability was compared with the multiple linear regression model and found superior. According to the developed Change of Score Method, the most frequent user attaches the highest importance to the service dimensions of the convenience to pay for the tram, getting his/her destination on time, and reducing environmental pollution.
Bankowy Arbitraż Konsumencki jako instytucja ochrony konsumenta na rynku usług bankowych
Authors: Piguła Ewelina
Published: April 2021

Problematyka ochrony konsumenta jest kluczowym czynnikiem rozwoju współczesnej gospodarki. Rynek usług finansowych podlega wpływowi konsumentów, dlatego znaczną rolę odgrywają także ich zachowania. Bardzo ważne jest jednak bezpieczeństwo klientów i skutki podejmowanych przez nich decyzji. Aby zapewnić konsumentom efektywną i skuteczną ochronę bardzo istotne jest funkcjonowanie obok struktur sądowych także systemu struktur rozjemczych stojących na straży praw i interesów konsumentów, które stanowią gwarancję uczciwych i zdrowych zasad obrotu gospodarczego w sferze usług bankowych. Wśród instytucji, które mogą odegrać bardzo dużą rolę w tym zakresie, a które są charakterystyczne tylko dla sektora bankowego, należy wskazać Bankowy Arbitraż Konsumencki oraz utworzony w 2008 r. Sąd Polubowny przy KNF. Ustawodawstwo przewiduje wiele źródeł ochrony interesów konsumentów na rynku usług bankowych, jednak nie wszystkie z nich są konsumentom znane i wykorzystywane w praktyce. Jednym z często pomijanych organów ochrony konsumentów usług bankowych jest BAK – Bankowy Arbitraż Konsumencki. W poniższym artykule przedstawiono instytucję Bankowego Arbitrażu Konsumenckiego jako organu o dużym znaczeniu dla ochrony konsumenta, pozwalającym na pozasądowe rozwiązywanie sporów. Celem artykułu jest przedstawienie i ocena funkcjonowania Bankowego Arbitrażu Konsumenckiego jako instytucji ochrony konsumenta na rynku usług bankowych. Hipoteza ta wymaga udowodnienia, które zostanie opracowane na podstawie badań własnych i literatury źródłowej.
Świadomość ubezpieczeniowa konsumentów w Polsce
Authors: Ratowska-Dziobiak Eleonora
Published: April 2021

Celem artykułu jest ocena zmian zachodzących w świadomości ubezpieczeniowej konsumentów na polskim rynku. Przeprowadzone badania fokusowe oraz wywiady eksperckie wskazują, że klienci cenią sobie kompleksową obsługę. Zdaniem rozmówców, uwzględnienie nowych zagrożeń, dostosowanie oferty do potrzeb nabywcy, a także wprowadzenie innowacji w sposobie dystrybucji, istotnie wpływa na wielkość popytu w zakresie usług ubezpieczeniowych.
Inheritance and Gene Effect of Resistance to Mungbean Yellow Mosaic Virus (MYMV) in Mungbean [Vigna radiata (L.) Wilczek]
Authors: Win K.S. , Win S. , Htun T.M. , Win N.K.K. , Oo K.S.
Published: April 2021

Background: Mungbean Yellow Mosaic Virus is one of the major constraints in mungbean production. Knowledge of mode of inheritance and gene effects of MYMV resistance is very useful and effective for the development of genotypes resistant to disease or incorporation of resistance into the desirable promising genotypes whichlack of disease resistance. Methods: In order to estimate inheritance pattern of MYMV disease resistance in mungbean, the study was conducted in summer season (2019) under natural condition. Six generations such as Pl, P2, Fl, BC1, BC2 and F2 of six combinations [two resistant genotypes (7639 and 10266) and three susceptible genotypes (7621, 10257 and R-021018)] were studied inheritance pattern of resistance to MYMV in segregation population. Result: Based on the result from mode of inheritance pattern of MYMV resistance, it can be concluded that single recessive gene is controlled the resistance of MYMV and susceptible behavior indicated as dominant over resistant. Additive gene action was the major role for the selection of MYMV resistance. Some differences in the expression of gene contributing for MYMV resistance from others findings might be attributed due to the sources of resistant genotypes which have different nature of resistant gene used in this investigation.
Diagnostic accuracy of cytology for canine osteosarcoma compared to histopathology
Authors: Oikonomidis Ioannis , Tsouloufi Theodora
Published: April 2021

PICO question

What is the sensitivity and specificity of cytology as a test for canine osteosarcoma when compared to histopathology as a gold standard?

 

Clinical bottom line

Category of research question

Diagnosis

The number and type of study designs reviewed

Overall, four diagnostic validity studies (two prospective and two retrospective) were critically appraised

Strength of evidence

Weak to moderate

Outcomes reported

There is evidence of moderate strength to support that cytology is highly sensitive and specific for diagnosing histologically confirmed osteosarcomas as mesenchymal malignant neoplasms (cytological diagnosis of sarcoma). Evidence of weak strength suggests that the sensitivity and specificity of cytology for identifying the exact histotype (cytological diagnosis of osteosarcoma) are low and high, respectively. Finally, there is currently evidence of weak strength indicating that the sensitivity and specificity of cytology are comparable to that of preoperative histopathology after incisional biopsy for the diagnosis of canine osteosarcoma

Conclusion

Based on the available evidence, the diagnostic accuracy of cytology in diagnosing histologically confirmed osteosarcomas as sarcomas is high, whereas a confident conclusion cannot be drawn regarding the diagnostic accuracy of cytology for the identification of the exact histotype (cytological diagnosis of osteosarcoma). There is currently scant evidence suggesting that cytology has comparable diagnostic accuracy to preoperative histopathology (i.e. after incisional biopsy) for the diagnosis of canine osteosarcomas, however, more studies are warranted to confirm these results

 

How to apply this evidence in practice

The application of evidence into practice should take into account multiple factors, not limited to: individual clinical expertise, patient’s circumstances and owners’ values, country, location or clinic where you work, the individual case in front of you, the availability of therapies and resources.

Knowledge Summaries are a resource to help reinforce or inform decision making. They do not override the responsibility or judgement of the practitioner to do what is best for the animal in their care.
Some aspects of ensuring national security in the information sphere
Authors: Paramonov Andrey V. , Kharin Vadim V.
Published: April 2021

The information environment is currently an indispensable part of life of society and state. Virtual space and new technologies not only make life easier and better for modern people, but also pose real and serious threats to national security. The virtual (non-existent) environment has a great impact on the real (practical) life of the individual, society and state. The danger lies in the fact that the state, represented by its bodies and officials, does not have time to create and correct the legislative framework for counteraction in time. We reveal that unified measures, as well as the unity of the policy in the field of information security in the world at the level of the UN Declarations and Conventions, have not been adopted, therefore, countering virtual threats, as well as ensuring the security of the information environment, is imposed on regional and state systems ensuring national security. When analyze the fundamental documents for ensuring the national security of the Russian Federation in the virtual sphere, it is revealed that the legislator places the main emphasis on threats of informational influence from foreign states, without covering and not disclosing the entire volume and current state of possible negative phenomena and threats in this area.
Implementation of equality principle of convicts under the law in the norms regulating the institution of convicts’ departure outside the penitentiary: some issues and ways to solve them
Authors: Kovalev Nikolai S.
Published: April 2021

One of the areas of effective legal regulation of penal legal relations is the compliance of lawmaking and law-enforcement activities with the requirements of the fundamental provisions of penal legislation. The object of the research is the implementation of the equality principle of convicts un-der the law through the consolidation of equal rights, duties and legitimate in-terests of convicts in the penal legislation. The subject of the research is the penal legislation norms governing the institution of the convicts’ departure outside the penitentiary. We indicate the connection of the phenomenon un-der study with the lawmaking and law-enforcement aspect of penal law. We outline some of the law-making and law-enforcement penal issues that are directly related to the consolidation and application of the penal legislation norms when granting convicts the right to leave the penitentiary to visit chil-dren. As a methodological basis for cognition, the following are used: general scientific methods of analysis, synthesis, induction, deduction, which make it possible to investigate aspects of penal legal reality directly related to the im-plementation of the principles of penal legislation, to formulate well-grounded conclusions; private scientific methods – formal legal and comparative legal – make it possible to identify problems of legal regulation, develop proposals for changing legislation. As a result of the study, we identify the penal legislation norms that contradict the equality principle of convicts under the law, and propose ways to eliminate the identified contradictions.
Revisão Narrativa sobre Choque na Sala de Emergência
Authors: Dantas Jorge , Vaz Rita , Morais Rui , Verdasca Irene
Published: April 2021

O doente em choque representa um desafio clínico comum na sala de emergência, e representa uma potencial situação de risco de vida imediato que requer a intervenção de diferentes especialidades médicas na sua estabilização. Neste trabalho realiza-se uma revisão não sistemática de recomendações internacionais e de literatura adicional sobre este tema, sob a perspectiva da abordagem ao doente na sala de emergência e das particularidades deste contexto. Esta revisão é estruturada segundo uma proposta de protocolo de actuação baseada no diagnóstico precoce do quadro de choque, na identificação do tipo de choque e da etiologia mais provável, bem como na instituição de terapêutica de suporte. É destacada a importância da estabilização inicial do doente ser orientada pela identificação dos mecanismos fisiológicos em falência, e identificadas estratégias que, fazendo pouco sentido noutros contextos, podem ter interesse na sala de emergência - dado serem práticas e de rápida implementação - como é o caso da administração defármacos vasoactivos por via periférica ou em bólus.
O sincretismo do morfema -r em latim
Authors: Gonçalves Lydsson Agostinho , Armelin Paula Roberta Gabbai
Published: April 2021

Este trabalho investiga o sincretismo da morfologia passiva em latim. Nessa língua, o sufixo que realiza a voz passiva (default: -r) também é encontrado em construções impessoais, anticausativas, contextos médios e verbos depoentes. Parte-se dos trabalhos de Schäfer (2008) e Lazzarini-Cyrino (2015) e, sob o modelo da Morfologia Distribuída (HALLE & MARANTZ, 1993; MARANTZ, 1997), apresenta-se uma proposta de derivação que postula que a marca sincrética é um argumento verbal não referencial – uma variável – incorporado ao verbo pós-sintaticamente. Os diversos contextos interpretativos em que a marca aparece resultam da posição original que esse argumento ocupava e da sua interação com diferentes sabores de Voice (FOLLI & HARLEY, 2005). Sendo a variável um argumento externo, não há outro DP para ela se ligar, e ela fica sem papel-θ e Caso. Sem papel-θ, a variável é lida como um expletivo em LF. A ausência de Caso, por sua vez, é um problema para PF (LEVIN, 2015) e, para que a derivação não seja perdida, a variável se incorpora ao domínio verbal via Deslocamento Local, nos termos de Levin (2015). A voz passiva e os impessoais resultam da incorporação da variável na posição de argumento externo de um VoiceDO. A mesma configuração, mas com um VoiceCAUSE, gera os anticausativos. Nos contextos médios, a variável também nasce na posição de argumento externo, mas é o argumento de um núcleo Appl (PYLKKÄNEN, 2008) que é promovido a sujeito sintático. Os depoentes se dividem em três tipos: propõe-se que os agentivos são, em verdade, médios, sendo derivados como eles; os depoentes de sujeitos experienciadores projetam esse argumento via um núcleo específico que chamamos de EXP e a variável ocupa a posição de argumento externo canônico; depoentes anticausativos resultam da incorporação do argumento de Appl ou EXP, mas em uma estrutura sem Voice.
Physicalische Beschreibung der Canarischen Inseln de von Buch y la terminología de la traducción al español de Delgado Luis
Authors: Monterde Rey Ana María
Published: April 2021

El objeto de este artículo es analizar la terminología de la única traducción completa al español de "Physicalische Beschreibung der Canarischen Inseln de von Buch" efectuada por Delgado Luis (von Buch, 1999). Con este fin, efectuamos un vaciado terminológico de la obra con SDL MultiTerm Extract de Trados y creamos una base datos con MultiTerm. A partir de ella, estudiamos los términos empleados en la traducción: densidad terminológica, métodos de formación de términos y estrategias de traducción. Con ello determinamos la adecuación terminológica de la obra traducida aportando, así, un nuevo conocimiento de esta importante obra.
Interdisciplinariedad y agresividad. Características del lenguaje de la fotografía en lengua inglesa
Authors: Mykytka Iryna
Published: April 2021

El presente estudio aspira a explorar el lenguaje de la fotografía. En particular, pretende descubrir los principales rasgos léxico-semánticos del inglés de la fotografía. Se trata de un estudio de carácter cualitativo, basado en corpus de casi un millón de palabras cuyas fuentes han sido blogs sobre la fotografía, escritos por fotógrafos profesionales y nativos. Los resultados demuestran que se trata de un léxico de gran riqueza y variedad. Por una parte, destaca su carácter interdisciplinario; la fotografía no se limita a usar sus propias palabras, sino que comparte gran número de voces con otras disciplinas. Hemos localizado numerosos ejemplos de palabras heredadas del campo de la pintura, óptica, informática, entre otros. Por otra parte, hemos concluido que el lenguaje fotográfico presenta un carácter agresivo. Este estudio pretende contribuir por un lado al campo del Inglés para Fines Específicos, y, por el otro, a la fotografía, cuya importancia en la sociedad actual está creciendo.
Zerrillo, Philip. (2019). The Case for Cases. Teaching with Cases. How to Teach Using the Case Method. Singapore: World Scientific. ISBN: 9789813273344. 94 pp.
Authors: Almagro Esteban Ana
Published: April 2021

Publicación de suma utilidad para a un amplio espectro de profesores, recién iniciados y no tan noveles, que aplican el Método del Caso en la enseñanza de lenguas. Así, este manual de reciente aparición en el mercado editorial se centra en las tres Ps del Método del Caso según Zerrillo (2019), esto es, Plan, Prepare y Perform; se distingue por su carácter eminentemente práctico.
Características epidemiológicas, clínicas, pre y posnatales de los neonatos, hijos de madre con la Covid-19, y del seguimiento hasta los 14 días post alta, en Lima-Perú
Authors: Lizama Olga , Mucha Jorge , Chincaro Maria del Carmen , Giraldo Gaby , Salazar José , Agüero Karenina , García César , Ulloa José , Espinoza Diana
Published: April 2021

Objetivo: Describir las características clínicas prenatales y post natales de los neonatos hijos de madres con la Covid-19, y seguimiento hasta los 14 días post alta. Material y métodos: Estudio tipo observacional, serie de casos, censal de los neonatos nacidos en el Hospital Guillermo Almenara Irigoyen, hijos de madres con la Covid-19, que nacieron durante la cuarentena decretada por el gobierno peruano. Los neonatos se dividieron en 2 grupos: con la prueba PCR nasofaríngea positiva o no y se observó si alguna de estas características estuvieron asociadas con la presentación de esta prueba positiva. Resultados: Hubieron 201 gestantes con diagnóstico de Covid-19 por prueba rápida y que tuvieron 206 neonatos. De ellos,  4 neonatos tuvieron la PCR nasofaríngea positiva y 202, negativa. La edad materna fue menor en el grupo con la prueba positiva, pero no hubo diferencia respecto al tipo de parto: césarea, fueron a termino, con adecuado peso al nacer y ningún sexo predominó. Doscientos cinco (99,51%) neonatos salieron de alta en la primera semana de vida; 181 (90,05%) neonatos con PCR nasofaríngea negativa y los4 neonatos con prueba positiva fueron seguidos por 2 semanas; ninguno presentó síntomas y el tipo de lactancia fue mixta. Conclusiones: Los neonatos hijos de madres con la Covid-19, tendrían una mínima posibilidad de contraer esta enfermedad. Y su desarrollo prenatal y post natal no se vería afectado, a pesar de incluso tener la prueba PCR nasofaríngea positiva.
Estrategia didáctica para mejorar el estilo de aprendizaje en estudiantes de la carrera de cosmética dermatológica en un instituto público de Lima
Authors:   , Llactahuaman Chavelon Nalda
Published: April 2021

El objetivo general de la investigación es diseñar una estrategia didáctica para mejorar el estilo de aprendizaje en estudiantes del I Ciclo de la Carrera Cosmética Dermatológica del instituto superior tecnológico público de Lima. Tiene un paradigma socio crítico interpretativo y un enfoque cualitativo aplicada educacional, dada la existencia de una relación lógica entre el objeto y el sujeto. Con el fin de dar una respuesta al estudio, se aplicó métodos cualitativos y cuantitativos para buscar la objetividad del problema para su posterior análisis y la transformación de la realidad educativa. El objeto de estudio está fundamentado a nivel científico en relación a las categorías apriorísticas, estrategias didácticas y estilo de aprendizaje, la muestra de estudio que se seleccionó a través del muestreo no probabilístico, consta de dos docentes que desarrollan unidades didácticas del primer ciclo y 15 estudiantes del turno diurno y nocturno. Para el diagnóstico de campo se empleó instrumentos y técnicas, una guía de observación de clases, un cuestionario a los estudiantes y una entrevista que se aplicó a los docentes. El resultado aporta información valiosa y específica sobre las carencias y fortalezas con respecto a los problemas que se identificaron a partir de las categorías emergentes, la propuesta de la investigación es el diseño de tres sesiones de clases, que serán usadas como estrategia didáctica, cuya base científica se encuentra en el marco teórico de la investigación.
Propiedades psicométricas del cuestionario de calidad de vida QLQ-BR23 en pacientes con Cáncer de Mama
Authors:   , Ramírez Polanco Adriana Salomé Fernanda , Rúa Lizárraga Astrid Montserrat
Published: April 2021

El objetivo del presente estudio fue hallar evidencias de las propiedades psicométricas del Cuestionario de Calidad de Vida – Módulo Cáncer de Mama (QLQ-BR23). La muestra se constituyó por 150 pacientes mujeres con cáncer de mama (CaM) entre 28 a 85 años (M=50.40) del Instituto Nacional de Enfermedades Neoplásicas. Se halló evidencias de validez vinculadas al contenido por criterio de jueces, y en cuanto a las evidencias de validez con relación estructura interna se optó por el análisis factorial exploratorio (AFE). En cuanto a los resultados asociados a las evidencias de validez de contenido se obtuvo una V de Aiken para relevancia (V > .95) y claridad (V > .85); mediante el procedimiento analítico-factorial se eliminaron 6 ítems (1, 2, 4, 6, 7 y 8) por presentar complejidad factorial (CF) lo que logró aumentar la varianza total explicada de 53.80 % a 61.61 %. La estructura final estuvo conformada por tres factores denominados Perspectiva Corporal (F1), Interés Sexual (F2) y Sintomatología Pre-diagnóstica y Peri-tratamiento (F3). Por último, los coeficientes de confiabilidad Alfa y Omega de las puntuaciones del constructo obtuvieron magnitudes adecuadas (>.70) para los factores de Perspectiva Corporal (F1) y Sintomatología Pre-diagnóstica y Peri-tratamiento (F3) a excepción del Interés Sexual (F2) con una magnitud aceptable (>.65) mientras que el coeficiente ORION obtuvo una magnitud alta (>.80) para todos los factores. En conclusión, se determinaron evidencias favorables de validez de contenido y de estructura interna del instrumento QLQ-BR23.
Organizacijske vještine managementa
Authors: Cicvarić Ante
Published: April 2021

Management je proces planiranja i odlučivanja, organiziranja, rukovođenja i kontrole ljudskih, financijskih, fizičkih i informacijskih potencijala poduzeća radi ostvarenja postavljenih ciljeva na efikasan i efektan način. Efikasan sustav managementa pretpostavlja jasnu podjelu rada, kompetentnost u donošenju odluka, stručnost i autoritet menadžera, kvalitetne informacije, odgovarajuće komunikacije, te sustav motivacije.
Marketing strategija uslužnih djelatnosti
Authors: Šunić Šime
Published: April 2021

Budući da se gospodarstvo sve više razvija u smjeru uslužnih djelatnosti, nameće se potreba da marketing manageri, marketing stručnjaci i poduzetnici, što bolje upoznaju uslužne djelatnosti i njihovu važnost za gospodarstvo svake zemlje, pa i Hrvatske. Usluge su neopipljive, nedjeljive, nepostojane i prolazne, pa svaki oblik usluga zahtijeva marketing strategiju. Naime, gospodarska uslužna djelatnost omogućava proizvodnji da premosti prostor ili segmente tržišta između proizvodnje i potrošnje, kako bi se u određenom vremenu i prostoru učinkovito zadovoljile potrebe potrošača i ostvarili ciljevi poduzeća, uz planiranu dobit ili profit. U prošlosti, uslužne djelatnosti su znatno zaostajale za proizvodnim poduzećima u usvajanju i primjeni marketing koncepcije, no sada se to znatno mijenja. Sukladno s iznesenim, marketing strategija u uslužnim djelatnostima zahtijeva ne samo vanjski marketing, već i marketing unutar poduzeća, kako bi se motivirali djelatnici u pružanju usluga i podizanju razine kvalitete.
A Sustainable, Integrated Multi-Level Floating Farm Concept: Singapore Perspective
Authors: Asgarov Rasim , MacLaren David , Hannan Mohammed Abdul , Khandelwal Prateek
Published: April 2021

The exponential growth of population and the consistent food demand has compelled humanity to seek alternatives to traditional farming and innovative technologies to increase production. Exploring offshore for natural resources and alleviating pressure on land has been an ongoing research field, especially in the energy and aquaculture sector. However, the idea of floating farming is still in its infancy and requires significant innovations. The work presented here shed further light on this area by proposing a comprehensive model of ‘Integrated, multicultural, Multileveled Floating Farm (MFF).’ Various aspects of planning, design, constructions and operations of such MFF are discussed. An integrated waste management system is proposed to improve sustainability. The conceptual design and associated financial analysis demonstrated that such integration of various modes of farming could be profitable and sustainable at the same time. The cost estimation and profit analysis are presented in the context of Singapore, and a conservative approach is followed for the calculation. However, the model can easily be extended for application in other countries.