bluuebunny/crossref_metadata_2025 huggingface dataset:
La Belgique, terre brassicole par excellence, entre modernité et tradition
Authors: Tilly Pierre
Published: October 2017

Les brasseurs peuvent se targuer de produire les meilleures bières au monde. La Belgique et sa longue tradition brassicole est considérée comme « le » pays de la bière, par excellence. Elle abrite le plus grand producteur mondial, Anheuser-Busch (AB) InBev basé à Leuven. Mais une des caractéristiques majeures du secteur est sa grande diversité et l’existence de grandes variétés d’entreprises qui constituent un grand atout en termes de qualité et d’expérimentation. Avant la Première Guerre mondiale, ce sont des entreprises locales et familiales qui dominent le marché belge mais la mise en perspective historique met en lumière la modification importante des structures du marché dans les années 1970 en raison d’une concurrence accrue et d’une vague inédite de concentration verticale et horizontale dans le secteur industriel brassicole. Toutefois des PME continuent d’exister et de se développer parallèlement à ces grandes entreprises en permettant le maintien d’une production artisanale. Ce qui donne aujourd’hui encore une coloration particulière au monde brassicole belge.
On the identity of Helianthemum mathezii and H. pomeridianum (Cistaceae)
Authors: Aparicio Abelardo , Albaladejo Rafael G.
Published: October 2017

The original description of Helianthemum mathezii regarded the species to be a therophyte. However, the detailed observation of the holotype of H. mathezii, as well as newly collected specimens from the type locality, does not support its condition of annual plant. Further study has led to the conclusion that all these plants can readily be identified as H. pomeridianum; the descriptions of H. mathezii and H. pomeridianum are equivalent except for the habit, being the former annual and the latter suffruticose. We show in this study that H. mathezii is to be considered a synonym of H. pomeridianum, and report a new locality of H. pomeridianum in Morocco. Also, we provide the first chromosome count for this species (2n = 22) which emphasizes the close relationship of H. pomeridianum to H. subgen. Plectolobum.
Bidirectional Spreading Activation Method for Finding Human Diseases Relatedness Using Well-Formed Disease Ontology
Authors: Fathalla Said , Kannot Yaman M. Khalid
Published: October 2017

The successful application of semantic web in medical informatics and the fast expanding of biomedical knowledge have prompted to the requirement for a standardized representation of knowledge and an efficient algorithm for querying this extensive information. Spreading activation algorithm is suitable to work on incomplete and large datasets. This article presents a method called SAOO (Spreading Activation over Ontology) which identifies the relatedness between two human diseases by applying spreading activation algorithm based on bidirectional search technique over large disease ontology. The proposed methodology is divided into two phases: Semantic matching and Disease relatedness detection. In Semantic Matching, semantically identify diseases in user's query in the ontology. In the Disease Relatedness Detection, URIs of the diseases are passed to the relatedness detector which returns the set of diseases that may connect them. The proposed method improves the non-semantic medical systems by considering semantic domain knowledge to infer diseases relatedness.
Exploring QSAR of Some Antitubercular Agents
Authors: Roy Partha Pratim , Singh Jagadish , Ray Supratim
Published: October 2017

The in vitro vero cell cytotoxicity of 93 antitubercular compounds belonging to the classes of chiral pentaamines, bis-cyclic guanidines, bis-cyclic thioureas, bis-cyclic piperazines, and quinolylhydrazones has been modeled in the present quantitative structure-activity relationship (QSAR) study. Genetic function approximation followed by multiple linear regression (GFA-MLR) based on the mean absolute error (MAE) based criteria was used as the chemometric tool for the model development using 2D descriptors available from open source PaDEL-Descriptor. The developed model was statistically robust (Q2:0.868, R2pred:0.896). Additionally, the r2m metrics, concordance correlation coefficient (CCC) and MAE criteria for the test set validation were also tested. The models indicate importance of autocorrelation descriptors weighted by charge (ATSc3, ATSc5) and some electrotopological state atom type descriptor of fragments -NH-,-O-, >N- for cytotoxicity. The applicability domains of GFA-MLR models were also studied by applying both leverage and standardized residual approaches.
Study of Pyrimidine-4-carboxamide Derivatives as HIV-1 Integrase Inhibitors Using QSAR and DFT Calculations
Authors: Elidrissi B. , Ousaa A. , Ghamali M. , Chtita S. , Ajana M. A. , Bouachrine M. , Lakhlifi T.
Published: October 2017

A Quantitative Structure–Activity Relationship (QSAR) study was performed to predict HIV-1 integrase inhibition activity (pIC50) of thirty-five 5-hydroxy-6-oxo-1,6-dihydropyrimidine-4-carboxamide compounds using the electronic and physico-chemical descriptors computed respectively, with Gaussian 03W and ACD/ChemSketch programs. The structures of all compounds were optimized using the hybrid Density Functional Theory (DFT) at the B3LYP/6-31G(d) level of theory. In both approaches, 28 compounds were assigned as the training set and the rest as the test set. These compounds were analyzed by the principal components analysis (PCA) method, the descendant Multiple Linear Regression (MLR) analyses and the Artificial Neural Network (ANN). The robustness of the obtained models was assessed by leave-many-out cross-validation, and external validation through a test set. This study shows that the MLR has served marginally better to predict pIC50 activity, when compared with the results given by predictions made with a (4-3-1) ANN model.
The relationship between physical fitness and community participation in people with spinal cord injury
Authors: Van Der Westhuizen Linda , Mothabeng Diphale J. , Nkwenika Tshifhiwa M.
Published: October 2017

Background: People with spinal cord injury (PWSCI) who use wheelchairs for mobility tend to be physically inactive because of their limited mobility. Poor endurance and exercise tolerance, associated with poor physical fitness, can make it challenging to meet the physical demands of activities such as manoeuvring a wheelchair over gravel roads. This may lead to poor community participation in activities PWSCI were involved in pre-morbidly. To date, no studies have been conducted in South Africa on what the relationship is between physical fitness and community participation in PWSCI.Aim: The purpose of this study was to establish the relationship between physical fitness and community participation in PWSCI.Methodology: An exploratory cross-sectional survey was conducted on PWSCI living in the Greater Tshwane Metropolitan City. Physical fitness was measured using the 6 minute push test (6MPT) and the Borg scale. Community participation was measured using the Reintegration to Normal Living Index (RNLI). The data were analysed using the Spearman’s Rank correlation at a 5% level of significance.Results: Moderate to poor associations were found between the 6MPT and the Borg scale with the RNLI (r = 0.637; p < 0.001 and r = −0.325; p = 0.013, respectively). These results indicate that the participants who were able to push further in 6 min and had better endurance were more satisfied with their perceived community participation.Conclusion: This study shows that there is a relationship between physical fitness and community participation in PWSCI. Information gained from this study lays the foundation for more studies in this area, and for possible improvement in rehabilitation practice.
Small Family with Key Contacts: Par14 and Par17 Parvulin Proteins, Relatives of Pin1, Now Emerge in Biomedical Research
Authors: Mueller Jonathan W , Bayer Peter
Published: October 2017

The parvulin-type peptidyl-prolyl cis/trans isomerase Pin1 is subject of intense biochemical and clinical research as it seems to be involved in the pathogenesis of certain cancers and protein folding illnesses like Alzheimer's and Parkinson's disease. In addition to Pin1, the human genome only contains a single other parvulin locus encoding two protein species–-Par14 and Par17. Much less is known about these enzymes although their sequences are highly conserved in all metazoans. Parvulin has been proposed to function as Pin1 complementing enzyme in cell cycle regulation and in chromatin remodelling. Pharmaceutical modulation of Par14 might therefore have benefits for certain types of cancer. Moreover, the Par17 protein that has been shown to be confined to anthropoid primate species only might provide a deeper understanding for human-specific brain development. This review aims at stimulating further research on Par14 and Par17 that are overlooked drug targets in the shadow of an overwhelming plethora of Pin1 literature by summarising all current knowledge on these parvulin proteins.
AIM-BLAST-AJAX Interfaced Multisequence Blast
Authors: Aravindhan G. , Kumar R. Sathish , Subha K. , Subazini T.K. , Dey Alpana , Kant Krishna , Kumar G. Ramesh
Published: October 2017

AIM-BLAST, AJAX Interfaced Multisequence Blast, is a simplified tool developed to facilitate the multiple sequences blast using AJAX as an interface. This tool has been integrated with the SOAP services of EBI NCBI Blast and the functionality of AJAX (Asynchronous Javascript and XML), so as to minimize the enormous bandwidth consumption while carrying out blast analysis for many sequences at an instance. Although a few tools for multiple sequences blast are already available online, they are restricted only to a limited number of genomes and consume several bytes of data transfer for receiving the results. Further, AIM-BLAST also has enhanced features for automated parsing of the Blast results of individual sequence and presenting them as “one sequence-one function” manner. This will save the users time and effort in interpreting the bulky blast results to identify one suitable hit. The results of the blast search in this tool are displayed in an easily interpretable table format that makes the tool user-friendly too. Hence this tool, with a laconic framework, will remain a well structured, flexible and a highly controlled Blast Program for investigating numerous sequences at a stretch with the consumption of reduced level of data transfer.
Oxidation of an Adjacent Methionine Residue Inhibits Regulatory Seryl-Phosphorylation of Pyruvate Dehydrogenase
Authors: Miernyk Jan A. , Johnston Mark L. , Huber Steve C. , Tovar-Méndez Alejandro , Hoyos Elizabeth , Randall Douglas D.
Published: October 2017

A Met residue is located adjacent to phosphorylation site 1 in the sequences of mitochondrial pyruvate dehydrogenase E1α subunits. When synthetic peptides including site 1 were treated with H2O2, the Met residue was oxidized to methionine sulfoxide (MetSO), and the peptides were no longer phosphorylated by E1α-kinase. Isolated mitochondria were incubated under state III or IV conditions, lysed, the pyruvate dehydrogenase complex (PDC) immunoprecipitated, and tryptic peptides analyzed by MALDI-TOF mass spectrometry. In all instances both Met and MetSO site 1 tryptic-peptides were detected. Similar results were obtained when suspension-cultured cells were incubated with chemical agents known to stimulate production of reactive oxygen species within the mitochondria. Treatment with these agents had no effect upon the amount of total PDC, but decreased the proportion of P-PDC. We propose that the redox-state of the Met residue adjacent to phosphorylation site 1 of pyruvate dehydrogenase contributes to overall regulation of PDC activity in vivo.
Lo tecnológico y la muerte. Supervivencias testamentarias en línea
Authors: Carolina Mazzetti Latini Carolina Mazzetti Latini , Emanuelli Paulina-Beatriz , Martínez Arcos Cruz Alberto
Published: October 2017

Con el propósito de trascender las posturas binarias, se ofrecen interrogantes para evidenciar la coexistencia de categorías que configuran una trama en tensión en torno a lo tecnológico. Metodología y discusión: A partir de un corpus teórico se abordan manifestaciones acerca de la muerte en entornos virtuales que, haciendo de la experiencia de la ausencia una presencia, dan cuenta de trasformaciones sustanciales en los procesos de comunicación. Resultados y conclusiones: La facilidad con que los vivos pueden mezclarse con los rastros transmisibles de los muertos, evidencia que lo tecnológico habilita la ruptura de ataduras no solo en cuanto a la distancia sino también en lo relativo a la muerte, recuperándola como intercambio social diacrónico.
Clear Skies Ahead
Authors: Somers Frederick P.
Published: October 2017

AJOT plays a vital role not just in raising the profile of the occupational therapy profession but also in furthering evidence-based practice.
Contribution of Coastal Retrogressive Thaw Slumps to the
Nearshore Organic Carbon budget along the Yukon Coast
Authors: Ramage Justine L. , Irrgang Anna M. , Morgenstern Anne , Lantuit Hugues
Published: October 2017

Abstract. We describe the evolution of coastal retrogressive thaw slumps (RTSs) between 1952 and 2011 along the Yukon Coast, Canada, and provide the first estimate of the contribution of RTSs to the nearshore organic carbon budget in this area. We 1) monitor the evolution of RTSs during the periods 1952–1972 and 1972–2011; 2) calculate the volume of material eroded and stocks of organic carbon (OC) mobilized through slumping – including soil organic carbon (SOC) and dissolved organic carbon (DOC) – and 3) measure the OC fluxes mobilized through slumping between 1972 and 2011. We identified 15 RTSs using high-resolution satellite imagery from 2011 and geocoded aerial photographs from 1952 and 1972. To estimate the volume of eroded material, we applied a spline interpolation on an airborne LiDAR dataset acquired in July 2013. We inferred the stocks of mobilized SOC and DOC from existing related literature. Our results show a 73 % increase in the number of RTSs between 1952 and 2011. In the study area, RTSs displaced at least 8600 × 103 m3 of material, with 53 % of ice. We estimated that slumping mobilized 81 900 × 103 kg of SOC and 156 × 103 kg of DOC. Since 1972, 17 % of the RTSs 20 have displaced 8.6 × 103 m3/yr of material, with an average OC flux of 82.5 ×103 kg/yr. This flux represents 0.3 % of the OC flux released from coastal retreat; however RTSs have a strong impact on the transformation of OC in the coastal fringe.
Quantifying the influence of the terrestrial biosphere on glacial–interglacial climate dynamics
Authors: Davies-Barnard Taraka , Ridgwell Andy , Singarayer Joy , Valdes Paul
Published: October 2017

Abstract. The terrestrial biosphere is thought to be a key component in the climatic variability seen in the palaeo-record. It has a direct impact on surface temperature through changes in surface albedo and evapotranspiration (so-called biogeophysical effects) and, in addition, has an important indirect effect through changes in vegetation and soil carbon storage (biogeochemical effects) and hence modulates the concentrations of greenhouse gases in the atmosphere. The biogeochemical and biogeophysical effects generally have opposite signs, meaning that the terrestrial biosphere could potentially have played only a very minor role in the dynamics of the glacial–interglacial cycles of the late Quaternary. Here we use a fully coupled dynamic atmosphere–ocean–vegetation general circulation model (GCM) to generate a set of 62 equilibrium simulations spanning the last 120 kyr. The analysis of these simulations elucidates the relative importance of the biogeophysical versus biogeochemical terrestrial biosphere interactions with climate. We find that the biogeophysical effects of vegetation account for up to an additional −0.91 °C global mean cooling, with regional cooling as large as −5 °C, but with considerable variability across the glacial–interglacial cycle. By comparison, while opposite in sign, our model estimates of the biogeochemical impacts are substantially smaller in magnitude. Offline simulations show a maximum of +0.33 °C warming due to an increase of 25 ppm above our (pre-industrial) baseline atmospheric CO2 mixing ratio. In contrast to shorter (century) timescale projections of future terrestrial biosphere response where direct and indirect responses may at times cancel out, we find that the biogeophysical effects consistently and strongly dominate the biogeochemical effect over the inter-glacial cycle. On average across the period, the terrestrial biosphere has a −0.26 °C effect on temperature, with −0.58 °C at the Last Glacial Maximum. Depending on assumptions made about the destination of terrestrial carbon under ice sheets and where sea level has changed, the average terrestrial biosphere contribution over the last 120 kyr could be as much as −50 °C and −0.83 °C at the Last Glacial Maximum.
Transfer of environmental signals from the surface to the underground at Ascunsă Cave, Romania
Authors: Drăguşin Virgil , Balan Sorin , Blamart Dominique , Forray Ferenc Lázár , Marin Constantin , Mirea Ionuţ , Nagavciuc Viorica , Orăşeanu Iancu , Perşoiu Aurel , Tîrlă Laura , Tudorache Alin , Vlaicu Marius
Published: October 2017

Abstract. We present here the results of a 4-year environmental monitoring program at Ascunsă Cave (southwestern Romania) designed to help us understand how climate information is transferred through the karst system and archived by speleothems. The air temperature inside the cave is around 7 °C, with slight differences between the upper and lower parts of the main passage. CO2 concentrations in cave air have a seasonal signal, with summer minima and winter maxima. These might indicate the existence of an organic matter reservoir deep within the epikarst that continues to decompose over the winter, and CO2 concentrations are possibly modulated by seasonal differences in cave ventilation. The maximum values of CO2 show a rise after the summer of 2014, from around 2000 to about 3500 ppm, following a rise in surface temperature. Using two newly designed types of water–air equilibrators, we were able to determine the concentration of CO2 dissolved in drip water by measuring its concentration in the equilibrator headspace and then using Henry's law to calculate its concentration in water. This method opens the possibility of continuous data logging using infrared technology, without the need for costly and less reliable chemical determinations. The local meteoric water line (δ2H  =  7.7 δ18O + 10.1), constructed using monthly aggregated rainfall samples, is similar to the global one, revealing the Atlantic as the strongly dominant vapor source. The deuterium excess values, as high as 17 ‰, indicate that precipitation has an important evaporative component, possibly given by moisture recycling over the European continent. The variability of stable isotopes in drip water is similar at all points inside the cave, suggesting that the monitored drip sites are draining a homogenous reservoir. Drip rates, as well as stable isotopes, indicate that the transfer time of water from the surface is on the order of a few days.
Development of a comprehensive database of scattering environmental conditions and simulation constraints for offshore wind turbines
Authors: Hübler Clemens , Gebhardt Cristian Guillermo , Rolfes Raimund
Published: October 2017

Abstract. For the design and optimisation of offshore wind turbines, the knowledge of realistic environmental conditions and utilisation of well-founded simulation constraints is very important, as both influence the structural behaviour and power output in numerical simulations. However, real high-quality data, especially for research purposes, are scarcely available. This is why, in this work, a comprehensive database of 13 environmental conditions at wind turbine locations in the North and Baltic Sea is derived using data of the FINO research platforms. For simulation constraints, like the simulation length and the time of initial simulation transients, well-founded recommendations in the literature are also rare. Nevertheless, it is known that the choice of simulation lengths and times of initial transients fundamentally affects the quality and computing time of simulations. For this reason, studies of convergence for both parameters are conducted to determine adequate values depending on the type of substructure, the wind speed, and the considered loading (fatigue or ultimate). As the main purpose of both the database and the simulation constraints is to compromise realistic data for probabilistic design approaches and to serve as a guidance for further studies in order to enable more realistic and accurate simulations, all results are freely available and easy to apply.
Application of a Monte Carlo Procedure for Probabilistic Fatigue Design of Floating Offshore Wind Turbines
Authors: Müller Kolja , Cheng Po Wen
Published: October 2017

Abstract. Fatigue load assessment of floating offshore wind turbines poses new challenges on the feasibility of numerical procedures. Due to the increased sensitivity of the considered system with respect to the environmental conditions from wind and ocean, the application of common procedures used for fixed-bottom structures results in either inaccurate simulation results or hard-to-quantify conservatism in the system design. Monte Carlo based sampling procedures provide a more realistic approach to deal with the large variation of the environmental conditions, although basic randomization has shown slow convergence. Specialized sampling methods allow efficient coverage of the complete design space, resulting in faster convergence and hence a reduced number of required simulations. In this study, a quasi-random sampling approach based on Sobol’ sequences is applied to select representative events for the determination of the lifetime damage. This is calculated applying Monte-Carlo integration, using subsets of a resulting total of 16 200 coupled time-domain simulations performed with the simulation code FAST. The considered system is the DTU 10 MW reference turbine installed on the LIFES50+ OO-Star Wind Floater Semi 10 MW floating platform. Statistical properties of the considered environmental parameters (i.e. wind speed, wave height and wave period) are determined based on the measurement data from Gulf of Maine, USA. Convergence analyses show that it is sufficient to perform around 200 simulations in order to reach less than 10 % uncertainty of lifetime fatigue damage equivalent loading. Complementary in-depth investigation is performed focusing on the load sensitivity and the impact of outliers. Recommendations for the implementation of the proposed methodology in the design process are also provided.
SÍNDROME DE BURNOUT: UMA REFLEXÃO LITERÁRIA SOBRE A OCORRÊNCIA EM DOCENTES DO ENSINO SUPERIOR dói10.5216/rir.v6i1.41568
Authors: Ferreira Francielly Damaris , Borges Cristiane José
Published: October 2017

Vivemos num momento em que o ambiente profissional prioriza valores econômicos em detrimento dos humanos. Esse fato acaba promovendo um esgotamento físico e mental nos indivíduos, sendo que este está cada vez mais relacionado ao trabalho, quando o mesmo não lhe proporciona condições adequadas. Uma profissão relacionada ao cuidado e dedicação ao outro, como a docência, acaba sendo alvo de comprometimento psíquico com o passar dos anos. Assim sendo, diversos autores têm-se dedicado ao estudo e ao conhecimento das variáveis que contribuem para o desenvolvimento de burnoutem professores. Portanto, este estudo busca, por meio de revisão da literatura/descritiva, identificar a produção cientifica atual sobre o assunto e verificar os consensos e as controvérsias. Os efeitos desta psicopatologia podem prejudicar o profissional docente em três níveis: individual, profissional e organizacional. Mais estudos devem ser realizados, a fim de que as mudanças organizacionais necessárias à redução deste problema sejam baseadas em evidências científicas.
University Students' Knowledge about Diabetes' Causes, Symptoms and Treatments
Authors: Alnajadat Hussain Matrook
Published: October 2017

The purpose of this study is to investigate the degree of knowledge of the students at Tafila Technical University (TTU) about diabetes in terms of its causes, symptoms and treatments. The sample of the study consisted of 171 male and female students enrolled at the Faculty of Educational Sciences for the academic year 2015/2016. To achieve the aims of the study, the researcher developed a questionnaire consisting of 25 items distributed over two groups, ten items consisted of four multiple answers, while the other 15 ones were based on a yes–or-no pattern verified by the norms of honesty and consistency. The results of the study showed that there were statistically significant differences in the degree of knowledge of the students about diabetes, attributed to first-degree relatives with diabetes or not. In addition, the results also showed that there were no statistically significant differences in the degree of knowledge about diabetes attributed to gender, major and academic year.
New records of the rare gastropods Erato voluta and Simnia patula, and first record of Simnia hiscocki from Norway
Authors: Sneli Jon-Arne , Bakken Torkild
Published: October 2017

New records of rare gastropod species are reported. A live specimen of Erato voluta (Gastropoda: Triviidae), a species considered to have a far more southern distribution, has been found from outside the Trondheimsfjord. The specimen was sampled from a gravel habitat with Modiolus shells at 49–94 m depth, and was found among compound ascidians, its typical food resource. Live specimens of Simnia patula (Caenogastropoda: Ovulidae) have during the later years repeatedly been observed on locations on the coast of central Norway, which is documented by in situ observations. In Egersund on the southwest coast of Norway a specimen of Simnia hiscocki was in March 2017 observed for the first time from Norwegian waters, a species earlier only found on the south-west coast of England. Also this was documented by pictures and in situ observations. The specimen of Simnia hiscocki was for the first time found on the octocoral Swiftia pallida.
The Effect of Performance on Israeli Equity Fund Flows
Authors: Arbaa Ofer , Varon Eva , Benzion Uri
Published: October 2017

This paper examines the influence of past performance on Israeli equity mutual funds' net flows between January 2004 and July 2014, using the most recommended and reliable two-cluster regression methodology. Apparently, Israeli investors are more sensitive to risk adjusted returns than absolute returns and the most recent performance seems to be more influential on fund flows than on longer-term past performance. Moreover, investors flock to the latest winners and do not leave the funds with the poorest performance. The effect of past performance seems to be more salient on flows of advertised funds than of those with no advertisement.  The results in Israel augment the scant work on mutual fund flows outside the US and add support to a growing body of literature documenting irrational investor behavior worldwide.
Performance Evaluation of Religious Funds
Authors: Das Praveen , Rao S. P. Uma , Boudreaux Denis
Published: October 2017

This exploratory study uses monthly net return data from August 2008 to June 2015 on 5 actively managed religious funds to distinguish between luck and skill of fund managers. The main benchmark of this study is the Fama-French-five-factor-model (2013). First, the abnormal performance, alpha, αi, of the equally weighted mutual fund with the above five factor model is examined. Second, we use the bootstrapping simulation approach of Fama and French (2010), to separate manager’s skill from luck. Equally weighted fund exhibits skill.
Community Detection Using Node Attributes and Structural Patterns in Online Social Networks
Authors: Singh Bikash Chandra , Rahman Mohammad Muntasir , Miah Md Sipon , Baowaly Mrinal Kanti
Published: October 2017

Community detection in online social networks is a difficult but important phenomenon in term of revealing hidden relationships patterns among people so that we can understand human behaviors in term of social-economics perspectives. Community detection algorithms allow us to discover these types of patterns in online social networks. Identifying and detecting communities are not only of particular importance but also have immediate applications. For this reason, researchers have been intensively investigated to implement efficient algorithms to detect community in recent years. In this paper, we introduce set theory to address the community detection problem considering node attributes and network structural patterns. We also formulate probability theory to detect the overlapping community in online social network. Furthermore, we extend our focus on the comparative analysis on some existing community detection methods, which basically consider node attributes and edge contents for detecting community. We conduct comprehensive analysis on our framework so that we justify the performance of our proposed model. The experimental results show the effectiveness of the proposed approach.
Evaluating Suppliers/Consultants and Procuring Entities in the Landscape of Public Procurement in Bangladesh
Authors: Islam Shahidul
Published: October 2017

Developing professionalism in procurement, both in Public as well as in Private Sectors, is a challenge in the field of Public Procurement in Bangladesh. This paper discusses on application of Public Procurement Rules in Government Sector with an objective to develop a transparent, accountable and efficient procurement aiming at value for money with sustainable development in Bangladesh. Finally the study strives to identify the bottlenecks in implementing Public Procurement Rules in Bangladesh.
Sexismo y formación inicial del profesorado
Authors: Carretero Bermejo Raúl , Nolasco Hernández Alberto
Published: October 2017

Este trabajo, enmarcado dentro de un proyecto de investigación más amplio, tiene por objetivo fundamental conocer las creencias y las actitudes sexistas de los futuros docentes como responsables de la educación y como trasmisores ideológicos en el día de mañana.En el análisis que exponemos a continuación, la población de alumnos de Magisterio presentó creencias sexistas en más de un 75% de la muestra estudiada, lo que significa que más de un 75% de futuros docentes está en disposición de trasmitir esta ideología frente a las diversas propuestas legislativas que persiguen la igualdad. Las personas objeto de estudio han mostrado actitudes sexistas hostiles y también benévolas. Los resultados encontrados justifican la necesidad de programar acciones formativas y educativas concretas y explícitas para el colectivo de futuros docentes, con el fin de cambiar estas creencias y detener así la perpetuación y la trasmisión ideológica del sexismo. Por tanto, parece necesaria la inclusión de formación específica en género y sexismo, así como la programación y el diseño de los planes de estudio desde la perspectiva de género. Estos resultados también muestran la necesidad de conocer las actitudes sexistas, o no sexistas, de los enseñantes en activo, dado que, si se confirman estos resultados entre la población docente, las necesidades de formación también se extenderían al grupo de profesores que ejercen en la actualidad.
Consideraciones generales respecto a la necesidad de practicar una pedagogía sobre la finitud humana en la educación formal. Estudio de caso
Authors: Ramos Pla Anabel , Camats i Guàrdia Ramon
Published: October 2017

Actualmente, la pedagogía de la muerte es un tema formativo emergente, sobre todo en el ámbito español. Asimismo, la finitud humana continúa siendo un tabú que cuesta derribar, tanto socialmente como pedagógicamente. En contraposición a dicha circunstancia, apostamos por la necesidad de tratar la pedagogía de la finitud humana desde la conciencia de la muerte en el ámbito de la didáctica formal. La aportación presenta un estudio de caso realizado en dos centros docentes de Lleida (España), donde los profesionales de la educación, la psicología, la pedagogía y/o la psicopedagogía respondieron un cuestionario diseñado ex profeso. Los resultados del cuestionario y de las entrevistas llevadas a cabo reflejan que los enseñantes no se sienten suficientemente formados ni preparados para realizar acciones pedagógicas respecto a situaciones infantiles y juveniles de muerte y de duelo. Se apuesta, finalmente, por la formación docente específica y se proponen una serie de estrategias generales para poder afrontar dicha temática en contextos de educación formal. De este modo, se pretende romper el tabú al cual se enfrenta la muerte en la profesión docente y psicopedagógica.
Primary Cutaneous Acral CD8+ T-Cell Lymphoma
Authors: Hathuc Vivian M. , Hristov Alexandra C. , Smith Lauren B.
Published: October 2017

Primary cutaneous acral CD8+ T-cell lymphoma is a new provisional entity in the 2016 revision of the World Health Organization classification of lymphoid neoplasms. This is a challenging diagnosis because of its rarity, as well as its morphologic and immunophenotypic overlap with other CD8+ cytotoxic lymphoid proliferations. Appropriate classification of this entity is crucial because of its indolent clinical behavior compared with other CD8+ T-cell lymphomas. Knowledge of the clinical setting, sites of involvement, and morphologic features can aid in correct diagnosis. Here, we review the clinical and pathologic features of primary cutaneous acral CD8+ T-cell lymphoma with an emphasis on the differential diagnosis among other C8+ T-cell lymphomas.
As implicações da capacitação nas crenças de autoeficácia de gestores técnico-administrativos de uma instituição federal de educação superior
Authors: Cavalcante Keliane De Oliveira , Silva Anielson Barbosa da
Published: October 2017

The article aims to analyze the implications of training in self-efficacy beliefs of technical-administrative managers of a Federal institution of higher education (IFE). The research is qualitative in nature and was realized with 12 managers, using semi-structured interviews. The discourse analysis revealed perceptions of the subject on the implications of training in the beliefs of self-efficacy and in the development of competences. The survey results reveal the necessity of the IFE include in training processes, beyond the notion of competences, an analysis of managers' beliefs about their capabilities, through the exploration of self-efficacy construct as determinant in the planning of the actions of managerial development. About the links between the level of self-efficacy and managers training, it is concluded that the managers surveyed generate a positive impact in their work because on their self-efficacy beliefs, since the experiences contributed to give more security in carrying out the activities and helped them deal with the difficult situations and problem-solving processes. The study is expected to assist in the introduction of self-efficacy as a key construct in managerial development programmes.
Estrutura de propriedade e remuneração dos executivos
Authors: Theiss Viviane , Beuren Ilse Maria
Published: October 2017

The study aimed to verify the relationship of ownership structure with the compensation of executives of companies listed on the BMFBovespa. Descriptive research with quantitative approach was conducted from desk research on a sample of 172 companies which showed the necessary data for this study. Data collection was carried out in the Reference Form, both relating for executive compensation as the ownership structure. The results of the list of rights on the cash flows and excess control rights to the compensation of executives revealed that only excess control rights had negative relation to executive compensation. Thus, it is concluded that there is a negative relationship between ownership structure and the remuneration of executives of listed companies in Brazil, which indicates the more concentrated is the smallest property is executive compensation.
Valid Issues but Limited Scope: A Response to Kitchen and Berk's Research Commentary on Educational Technology
Authors: Clements Douglas H. , Sarama Julie
Published: October 2017

In their Research Commentary, Kitchen and Berk (2016) argue that educational technology may focus only on skills for low-income students and students of color, further limiting their opportunities to learn mathematical reasoning, and thus pose a challenge to realizing standards-based reforms. Although the authors share the concern about equity and about funds wasted by inappropriate purchases of technology before planning based on research and the wisdom of expert practice, including inadequate professional development, they believe that Kitchen and Berk's commentary contains several limitations that could be misconstrued and thus misdirect policy and practice.
Informal Content and Student Note-Taking in Advanced Mathematics Classes
Authors: Fukawa-Connelly Timothy , Weber Keith , Mejía-Ramos Juan Pablo
Published: October 2017

This study investigates 3 hypotheses about proof-based mathematics instruction: (a) that lectures include informal content (ways of thinking and reasoning about advanced mathematics that are not captured by formal symbolic statements), (b) that informal content is usually presented orally but not written on the board, and (c) that students do not record the informal content that is only stated orally but do if it is written on the board. The authors found that (a) informal content was common (with, on average, 32 instances per lecture), (b) most informal content was presented orally, and (c) typically students recorded written content while not recording oral content in their notes.
The Surgical Impact of E-Cigarettes: A Case Report and Review of the Current Literature
Authors: Fracol Megan , Dorfman Robert , Janes Lindsay , Kulkarni Swati , Bethke Kevin , Hansen Nora , Kim John
Published: October 2017

We report a case of a 51 years old female with a 25 pack year smoking history who underwent bilateral mastectomy and immediate tissue expander reconstruction for newly diagnosed right breast cancer. The patient reported herself as a non-smoker despite significant e-cigarette use, with resulting significant mastectomy skin flap necrosis and breast reconstruction failure. Little is known about the physiologic effect of e-cigarettes on wound healing and tissue perfusion. To this end, we provide an updated review of the impact of e-cigarettes on surgical outcomes. PubMed, Ovid MEDLINE, and PRS GO were searched for the terms “e-cigarette”, “electronic cigarette”, “e-cig”, “electronic nicotine delivery system”, “vaping”, “surgery”, “surgical”, “peri-operative”, “operate”, “operative”, and “wound healing”. Abstract review of all articles was performed. 123 articles returned that contained both variants of e-cigarettes and surgery as keywords. Of those, manual assessment returned three articles which were found to be relevant to e-cigarette use in the surgical patient. No articles were found that compared perioperative complications in e-cigarette versus traditional cigarette users in humans. In conclusion, our case report depicts the potential dangers associated with e-cigarette use in the surgical patient. There is a public misconception that e-cigarettes are healthier than traditional cigarettes and as such their use may go unreported by patients. Early evidence suggests e-cigarettes may induce some of the same physiologic changes as traditional cigarettes, and may have a significant deleterious effect on wound healing.
Serial Tissue Expansion at the Same Site in Pediatric Patients: Is the Subsequent Expansion Faster?
Authors: Lee Moon Ki , Park Seong Oh , Choi Tae Hyun
Published: October 2017

Background Serial tissue expansion is performed to remove giant congenital melanocytic nevi. However, there have been no studies comparing the expansion rate between the subsequent and preceding expansions. In this study, we analyzed the rate of expansion in accordance with the number of surgeries, expander location, expander size, and sex.

Methods A retrospective analysis was performed in pediatric patients who underwent tissue expansion for giant congenital melanocytic nevi. We tested four factors that may influence the expansion rate: The number of surgeries, expander location, expander size, and sex. The rate of expansion was calculated by dividing the ‘inflation amount’ by the ‘expander size’.

Results The expansion rate, compared with the first-time group, was 1.25 times higher in the second-or-more group (P=0.04) and 1.84 times higher in the third-or-more group (P<0.01). The expansion rate was higher at the trunk than at other sites (P<0.01). There was a tendency of lower expansion rate for larger expanders (P=0.03). Sex did not affect the expansion rate.

Conclusions There was a positive correlation between the number of surgeries and the expansion rate, a positive correlation between the expander location and the expansion rate, and a negative correlation between the expander size and the expansion rate.
The Effect of Low-Dose Nitroglycerin Ointment on Skin Flap Necrosis in Breast Reconstruction after Skin-Sparing or Nipple-Sparing Mastectomy
Authors: Yun Min Ho , Yoon Eul Sik , Lee Byung-Il , Park Seung-Ha
Published: October 2017

Background Skin flap necrosis is a common complication after mastectomy and breast reconstruction. It has been proven that nitroglycerin ointment, as a topical vasodilator, can decrease the rate of skin flap necrosis after mastectomy and breast reconstruction. However, nitroglycerin can cause several side effects, including headache, dizziness, and hypotension. The purpose of this study was to evaluate whether the application of a low dose of nitroglycerin ointment reduced the rate of skin flap necrosis in breast reconstruction after skin-sparing or nipple-sparing mastectomy.

Methods A total of 73 cases of breast reconstruction after nipple-sparing and skin-sparing mastectomy at our institution from March 2012 to January 2017 were retrospectively studied. Of these patients, 52 received nitroglycerin ointment (4.5 mg) application to the skin around the nipple-areolar complex from August 2015 to January 2017, while 21 received fusidic acid ointment from March 2012 to August 2015. The number of patients who experienced necrosis of the breast skin flap was counted in both groups.

Results Skin flap necrosis developed in 2 (3.8%) patients who were treated with nitroglycerin ointment and 5 (23.8%) patients who did not receive nitroglycerin ointment treatment. Patients who did not receive nitroglycerin ointment treatment had a significantly higher risk of mastectomy skin flap necrosis than patients who did (odds ratio=7.81; 95% confidence interval, 1.38 to 44.23; P=0.02).

Conclusions Low-dose nitroglycerin ointment administration significantly decreased the rate of skin flap necrosis in patients who underwent breast reconstruction after skin-sparing or nipple-sparing mastectomy, without increasing the incidence of the side effects of nitroglycerin.
How Vague Can Your Patent Be? Vagueness Strategies in U.S. Patents
Authors: Arinas Ismael
Published: October 2017

Patent claims define the protection scope of the intellectual property sought by the patent applicant or patentee. Broad claims are valuable as they can describe more expansive rights to the invention. Therefore, if these claims are too broad a potential infringer will more easily argue against them. But if the claims are too narrow the scope of protection of the intellectual property is greatly reduced. Patent claims have to be, on the one hand, determinate and precise enough and, on the other hand, as inclusive as possible. Therefore patent applicants must find a balance in the broadness of the scope defined by their claims. This balance can be achieved by the choice of words with a convenient degree of semantic indeterminacy, by the choice of modifiers or other strategies. In fact, vagueness in patent claims is a desirable characteristic for such documents. A quantitative and qualitative analysis of a corpus of 350 U.S. patents provides a promising starting point to understand the linguistic instruments used to achieve the balance between property claim scope and precision of property description. To conclude, some issues relating vagueness and pragmatics are suggested as a line of further research.
Using the Language of Wellbeing in the Care of the Elderly in Mexico
Authors: Sánchez-Escobedo Pedro , Viera-Castro Luz M.
Published: October 2017

The language we use with others derives from hidden assumptions about them and commands expectations and outcomes. That is why the constructs and language used in health services provided to the elderly are a worthwhile object of study.This paper addresses the language used in the services provided to the elderly population in Mexico and many other Latin-American countries. The psychological, linguistic and practical aspects of the wellbeing language paradigm are discussed. The linguistic analysis of the discourse used by health care providers conveys important implications to the kind, quality and purpose of intervention.It is argued that by using the language of wellness, health professionals are in a better position to listen and assess the degree of satisfaction and happiness, to explore for conditions that may promote or hinder quality of life, and also, they are in a better position for planning services to the elderly that reach beyond physical health and economic indicators.It is posited that quality of life in old age is incomplete without a sense of the patient’s wellbeing.
Le Château de Monte-Cristo : au carrefour de la macro et de la micro-histoire
Authors: Lefebvre Laurent
Published: October 2017

À travers l’analyse du château de Monte-Cristo, cet article permet de réfléchir au croisement de différentes échelles au sein d’un même travail historique. Nous cherchons à faire ressortir les apports d’une approche à la fois micro et macro-historique. Plus concrètement, nous nous pencherons sur l’intégration et sur l’interprétation de la situation socioculturelle internationale française d’Alexandre Dumas à Monte-Cristo (1844-1849). Notre réflexion se concentrera sur l’intégration des mouvements orientalistes et romantiques, mais aussi d’une culture européenne « commune » chez le célèbre écrivain.
Les tournants géographiques, le numérique et la pratique historienne
Authors: Dominic Laramée François
Published: October 2017

Les différentes facettes du tournant géographique initié par les disciples du philosophe Henri Lefebvre ont balayé l’ensemble des sciences humaines et sociales au cours des 30 ou 40 dernières années. Cet essai historiographique présente les précurseurs des tournants géographiques, leurs origines théoriques, les champs de recherche historiques dans lesquels ils se sont montrés particulièrement féconds, l’émergence récente des humanités spatiales qui combinent la sensibilité géographique avec les techniques d’analyse des humanités numériques, et quelques leçons à tirer de leurs enseignements.
Identification and functional characterization of muscle satellite cells in Drosophila
Authors: Chaturvedi Dhananjay , Reichert Heinrich , Gunage Rajesh D , VijayRaghavan K
Published: October 2017

Work on genetic model systems such as Drosophila and mouse has shown that the fundamental mechanisms of myogenesis are remarkably similar in vertebrates and invertebrates. Strikingly, however, satellite cells, the adult muscle stem cells that are essential for the regeneration of damaged muscles in vertebrates, have not been reported in invertebrates. In this study, we show that lineal descendants of muscle stem cells are present in adult muscle of Drosophila as small, unfused cells observed at the surface and in close proximity to the mature muscle fibers. Normally quiescent, following muscle fiber injury, we show that these cells express Zfh1 and engage in Notch-Delta-dependent proliferative activity and generate lineal descendant populations, which fuse with the injured muscle fiber. In view of strikingly similar morphological and functional features, we consider these novel cells to be the Drosophila equivalent of vertebrate muscle satellite cells.