bluuebunny/crossref_metadata_2025 huggingface dataset:
PENGARUH TEKNOLOGI AKUAPONIK DENGAN MEDIA TANAM SELADA (Lactuca sativa) YANG BERBEDA TERHADAP PERTUMBUHAN BELUT (Monopterus albus)
Authors: Anjani Pipin Tri , Kusdarwati Rahayu , Sudarno Sudarno
Published: June 2019

Teknologi akuaponik merupakan teknologi kombinasi akuakultur dan hidroponik yang bertujuan untuk memelihara ikan dan tanaman dalam satu sistem yang saling terhubung (Sibarani, 2013). Limbah yang dihasilkan oleh ikan seperti feses dan pakan, digunakan sebagai pupuk untuk tanaman. Kemudian air yang dialirkan dari media pemeliharaan dibersihkan olah tanaman sehingga dapat digunakan kembali oleh ikan (Wahap,2010). Menurut Rokocy (2010) interaksi antara ikan dan tanaman menghasilkan lingkungan yang ideal untuk tumbuh sehingga lebih produktif dari metode tradisional.Tujuan penelitian ini adalah untuk mengetahui pengaruh media tanam terhadap pertumbuhan belut (Monopterus albus) dalam sistem akuaponik. Penelitian ini dilakukan pada bulan Agustus sampai September 2016 di Fakultas Perikanan dan Kelautan Universitas Airlangga. Percobaan terdiri dari empat perlakuan dan lima ulangan, tanpa media tanam sebagai kontrol ( P0), media tanam zeolit (P1), media tanam batu apung (P2) dan media tanam pecahan batu bata (P3). Hasil pengamatan yang didapatkan dari penggunaan teknologi akuaponik dengan media tanam selada terbaik yang dapat mempengaruhi pertumbuhan belut yaitu media tanam zeolit. Pada pengamatan menunjukkan laju pertumbuhan spesifik dengan media tanam zeolit (1,19%/hari), kelulushidupan belut dengan media tanam zeolit (70%), Penambahan tinggi selada pada media tanam zeolit ( 11,39 cm), dan kandungan amonia terendah pada media tanam zeolit pada hari ke-28 (0,03 mg/L).
PENAMBAHAN LISIN PADA PAKAN KOMERSIAL TERHADAP LAJU PERTUMBUHAN, RASIO KONVERSI PAKAN DAN EFISIENSI PAKAN UDANG GALAH (Macrobrachium rosenbergii)
Authors: Pramana Andy , Agustono Agustono , Nurhajati Tri
Published: June 2019

Produksi nasional udang galah (Macrobrachium rosenbergii) di Indonesia hanya sekitar 400.000 ton hanya untuk memenuhi kebutuhan pasar domestik yang belum terpenuhi. Salah satu upaya untuk meningkatkan produksi dan produktivitas kegiatan budidaya udang air tawar dapat dilakukan dengan pengembangan pakan alternatif atau feed additive yang dapat mempercepat pertumbuhan sehingga memperpendek masa produksi. Lisin merupakan salah satu feed additive yang berperan dalam pembentukan karnitin. Karnitin berpengaruh pada pertumbuhan dan oksidasi lemak dalam udang. Penelitian ini bertujuan untuk mengetahui pengaruh penambahan lisin pada pakan komersial terhadap laju pertumbuhan, rasio konversi pakan dan efisiensi pakan udang galah (Macrobrachium rosenbergii). Perlakuan pada penelitian ini adalah pakan komersial tanpa penambahan lisin, pakan komersial dengan penambahan 0,5 %, pakan komersial dengan penambahan 1 %, pakan komersial dengan penambahan 1,5 % dan pakan komersial dengan penambahan 2 %. Penelitian ini menggunakan metode eksperimental dengan Rancangan Acak Lengkap (RAL). Analisa statistik menggunakan Analisis Varian (ANAVA) untuk mengetahui pengaruh perlakuan. Hasil penelitian menunjukkan bahwa penambahan lisin pada pakan komersial tidak berbeda nyata (p> 0,05) dari tingkat pertumbuhan, rasio konversi pakan dan efisiensi pakan udang galah (Macrobrachium rosenbergii). Kebutuhan protein dan lisin dalam udang galah belum terpenuhi sehingga laju pertumbuhan relatif lambat. Kualitas air udang media pemeliharaan oksigen terlarut 6,9-7,3 ppm, pH 7-8, suhu 29-30 ° C dan amonia 0-0,25 mg / l.
INFESTASI EKTOPARAIT PADA IKAN NILA (Oreochromis niloticus) YANG DIPELIHARA DENGAN MENGGUNAKAN SISTEM AKUAPONIK DAN TANPA AKUAPONIK
Authors: Putra Ewang Mahendra , Mahasri Gunanti , Sari Luthfiana Aprilianita
Published: June 2019

Penelitian ini bertujuan untuk mengetahui jenis ektoparasit dan perbedaan infestasi ektoparasit pada ikan nila (Oreochromis niloticus) yang dipelihara pada sistem akuaponik dan tanpa akuaponik. Metode penelitian rnenggunakan kuasi eksperimen intact-group comparison dengan terdapat dua perlakuan. Hewan uji menggunakan ikan nila dengan bobot 6-7 g/ekor. Hewan uji dipelihara di akuarium kaca berukuran 40cmx30cmx30cm yang diisi air sebanyak 15 liter. Perlakuan yang diberikan berupa pemeliharaan ikan nila dengan menggunakan sistem akuaponik dan pemeliharaan ikan nila tanpa menggunakan sistem akuaponik. Parameter yang diamati adalah jenis ektoparasit dan infestasi ektoparasit pada ikan nila. Jenis parasit yang ditemukan menginfestasi ikan nila (Oreochromis niloticus) pada pemeliharaan dengan menggunakan akuaponik maupun tanpa akuaponik adalah Argulus sp. Terdapat perbedaan yang nyata antara infestasi ektoparasit pada ikan nila (Oreochromis niloticus) yang dipelihara dengan sistem akuaponik dan tanpa akuaponik.
MANAJEMEN PEMBENIHAN LELE MUTIARA (Clarias sp.) DENGAN APLIKASI PROBIOTIK DI UNIT PELAYANAN TEKNIS PENGEMBANGAN TEKNOLOGI PERIKANAN BUDIDAYA (UPT PTPB) KEPANJEN, MALANG, JAWA TIMUR
Authors: Ardyanti Regita , Nindarwi Daruti Dinda , Sari Luthfiana Aprilianita , Wulan Sari Putri Desi
Published: June 2019

Lele (Clarias sp.) merupakan jenis ikan konsumsi air tawar dengan tubuh memanjang dan kulit licin. Ikan lele MUTIARA adalah strain baru ikan lele Afrika Clarias gariepinus Burchell, 1822 unggul hasil pemuliaan Badan Penelitian Pemuliaan Ikan (BPPI) Sukamandi yang telah dinyatakan lulus pada Penilaian Pelepasan Jenis/Varietas pada tanggal 27 Oktober 2014, dengan nama ikan lele MUTIARA (Mutu Tinggi Tiada Tara). Praktek Kerja Lapang ini dilaksanakan di Unit Pelayanan Teknis Pengembangan Teknologi Perikanan Budidaya Kepanjen, Kabupaten Malang, Jawa Timur pada tanggal 18 Januari - 12 Februari 2016. Praktek Kerja Lapang ini adalah metode partisipasi aktif dengan mengikuti secara langsung kegiatan yang dilakukan dilapangan. Pengambilan data dilakukan dengan cara observasi, wawancara dan partisipasi aktif. Hasil pengamatan menunjukkan bahwa manajemen pembenihan ikan lele mutiara dengan aplikasi probiotik dilakukan dengan pemijahan alami meliputi: persiapan kolam, seleksi induk, pemijahan, fase penetasan telur, pemeliharaan larva dan benih, pemberian pakan, pengendalian hama penyakit dan pembuatan pakan fermentasi. Manajemen Pembenihan Lele Mutiara (Clarias sp.)dilakukan secara alami dengan perbandingan induk jantan dan betina adalah 1 : 1. Jumlah telur yang dihasilkan adalah 71.648 butir, telur yang terbuahi adalah 47.376 butir dan telur yang berhasil menetas adalah 37.310 butir sehingga didapatkan Hatching Rate (HR) sebesar 78,7%. Kelangsungan hidup larva ikan gurami awal pemeliharaan larva berjumlah 37.310 ekor dan jumlah akhir pemeliharaan larva berjumlah 35.000 ekor sehingga didapatkan Survival Rate (SR) sebesar 93,80%.
MANAJEMEN PASCA PANEN KULTUR MIKROALGA Porphyridium cruentum PADA SKALA LABORATORIUM DAN SKALA INTERMEDIET DI BALAI BESAR PERIKANAN BUDIDAYA AIR PAYAU, JEPARA JAWA TENGAH
Authors: Putri Ayu Dyah Amini , Tjahjaningsih Wahju
Published: June 2019

Porphyridium cruentum merupakan salah satu jenis mikroalga dari kelas alga merah yang dapat memproduksi polisakarida dan mengandung beberapa pigmen. Pigmen yang terkandung di dalam P. cruentum memberikan kontribusi yang besar sebagai pewarna makanan dan pakan alami pada larva ikan. Salah satu pigmen yang terdapat pada P. cruentum adalah fikoeritrin. Tujuan praktek kerja lapang ini adalah mengetahui informasi, keterampilan lapangan dan masalah apa saja yang ada tentang manajemen pasca panen kultur mikroalga Porphyridium cruentum pada skala laboratorium dan skala intermediet di BBPBAP Jepara. Praktek Kerja Lapang ini telah dilaksanakan di Balai Besar Perikanan Budidaya Air Payau Jepara, Jawa Tengah pada tanggal 20 Januari - 20 Februari 2017. Metode kerja yang digunakan dalam praktek kerja lapang ini adalah metode deskriptif atau penguraian empiris dengan pendekatan kualitatif. Pengambilan data dilakukan dengan partisipasi aktif, wawancara, observasi dan studi pustaka. Kegiatan yang dilakukan selama praktek kerja lapang adalah proses sterilisasi alat dan bahan, mengkultur mikroalga, menghitung kepadatan mikroalga, memanen mikroalga, mengemas mikroalga, serta menganalisis kelayakan usaha. Berdasarkan perhitungan yang dilakukan, diperoleh pendapatan per siklus sebesar Rp14.760.000,00, Revenue Cost Ratio (R/C) adalah sebesar 1.835. Break Even Point (BEP) skala laboratorium sebesar 251.403 liter bibit, skala intermediet sebesar 12.570 liter bibit Payback period (PP) yang adalah 3.174 tahun atau 38.1 bulan
What is the Role of Internalizing and Externalizing Symptoms in Adolescent Suicide Behaviors?
Authors: Piqueras José A. , Soto-Sanz Victoria , Rodríguez-Marín Jesús , García-Oliva Carlos
Published: June 2019

Suicide is the second leading cause of death in adolescents and young adults aged 15 to 29 years. Specifically, the presence of internalizing and externalizing symptomatology is related to increased risk for suicide at these ages. Few studies have analyzed the relations between these symptoms and their role as mediators in predicting suicide behavior. This study aimed to examine the relation between internalizing and externalizing symptomatology and suicide behaviors through a longitudinal study. The sample consisted of 238 adolescents aged 12 to 18 years. The data were analyzed via PROCESS Statistical Package. The main results showed that previous depression symptoms had a significant indirect effect, through previous suicide behaviors and current depression symptoms, on current suicide behaviors, accounting for 61% of the total variance explained. Additionally, being a girl increased this risk. Therefore, the implementation of early identification and intervention programs to address youth symptoms of depression and suicidal behaviors could significantly reduce the risk for future suicidal behaviors in adolescence.
Efficiency of Artificial Neural Networks in Determining Scour Depth at Composite Bridge Piers
Authors: Amini Ata , Hamidi Shahriar , Malek Marlinda , Mohammad Thamer , Shirzadi Ataollah , Behmanesh Javad
Published: June 2019

Scouring is the most common cause of bridge failure. This study was conducted to evaluate the efficiency of the Artificial Neural Networks (ANN) in determining scour depth around composite bridge piers. The experimental data, attained in different conditions and various pile cap locations, were used to obtain the ANN model and to compare the results of the model with most well-known empirical, HEC-18 and FDOT, methods. The data were divided into training and evaluation sets. The ANN models were trained using the experimental data, and their efficiency was evaluated using statistical test. The results showed that to estimate scour at the composite piers, feedforward propagation network with three neurons in the hidden layer and hyperbolic sigmoid tangent transfer function was with the highest accuracy. The results also indicated a better estimation of the scour depth by the proposed ANN than the empirical methods.
Coherently Driven and Superdirective Antennas
Authors: Krasnok Alex
Published: June 2019

Antennas are crucial elements for wireless technologies, communications and power transfer across the entire spectrum of electromagnetic waves, including radio, microwaves, THz and optics. In this paper, we review our recent achievements in two promising areas: coherently enhanced wireless power transfer (WPT) and superdirective dielectric antennas. We show that the concept of coherently enhanced WPT allows improvement of the antenna receiving efficiency by coherent excitation of the outcoupling waveguide with a backward propagating guided mode with a specific amplitude and phase. Antennas with the superdirectivity effect can increase the WPT systems performance in another way, through tailoring of radiation diagram via engineering antenna multipoles excitation and interference of their radiation. We demonstrate a way to achieving the superdirectivity effect via higher-order multipoles excitation in a subwavelength high-index spherical dielectric resonator supporting electric and magnetic Mie multipoles. Thus, both types of antenna discussed here possess a coherent nature and can be used in modern intelligent antenna systems.
A Meso-Scale Approach to Estimating Vertical Mixing Induced by Wind–Waves
Authors: Polnikov Vladislav
Published: June 2019

The aim of work is to derive an explicit expression for a function of vertical mixing induced by wind-waves. To this end, in the Navier-Stokes equations, a current is decomposed into four constituents: the mean flow, the wave-orbital motion, the wave-induced turbulent and the background turbulent currents. This decomposition allows separating the wave-induced Reynolds stress, Rw, from the background one, Rb. To make a statistical closure for Rw, the Prandtl approach for the background turbulent fluctuations is used that results in an implicit expression for the wave-induced vertical mixing function, Bv. Expression for Bv is specified based on the author’s results for the eddy viscosity found earlier in the frame of the three-layer concept for a wavy air–sea interface, used for modelling wind-drift currents [1]. Finally, the explicit parameterization for Bv(a, u*, z) is found as a linear function in both the wave amplitude at depth z, a(z), and the friction velocity in the air, u*. The linear dependence of function Bv(a) on the wave amplitude provides the enhanced vertical mixing induced by wind–waves in comparison with function Bv(a) having the cubic dependence found in [2], as far as the wind-wave amplitude a(z) decays exponentially with depth.
Non-Intrusive Load Disaggregation by Linear Classifier Group Considering Multi-Feature Integration
Authors: Yu Jinying , Wu Yuxin , Su Chang
Published: June 2019

Non-intrusive load monitoring (NILM) is a core technology for demand response (DR) and energy conservation services. Traditional NILM methods are rarely combined with practical applications, and most studies aim to decompose the whole loads in a household, which leads to low identification accuracy. In this paper, an NILM approach based on multi-feature integrated classification (MFIC) is explored, which combines some non-electrical features such as ON/OFF duration, usage frequency of appliances, and usage period to improve load differentiability. The implementation of MFIC algorithm is consistent with traditional event-based method. The uniqueness of our algorithm is that it designs an event detector based on steady-state segmentation and a linear discriminant classifier group based on multi-feature global similarity. Simulation results using an open-access dataset demonstrate the effectiveness and high accuracy of MFIC algorithm, with the state-of-the-art NILM methods as benchmarks.
STUDI EKSPERIMENTAL PENGARUH PENAMBAHAN BAMBU PETUNG SEBAGAI FIBER TERHADAP KUAT LEKAT BETON SERAT PASCA BAKAR
Authors: Nurhidayati Aryanti
Published: June 2019

Tujuan dari penelitian ini untuk (1) mengetahui pengaruh penambahan variasi panjang serat bambu terhadap kuat lekat beton pasca bakar; (2) mengetahui ukuran serat bambu dan suhu pembakaran optimal yang menghasilkan kuat lekat maksimal pada beton serat pasca bakar. Penelitian menggunakan metode kuantitatif eksperimen dan teknik analisa data secara deskriptif. Variabel yang mempengaruhi dalam penelitian ini adalah (1) Variabel bebas : (a) variasi penambahan serat bambu yaitu 20 x 1 x 1mm, 30 x 1 x 1mm, dan 40 x 1 x 1mm, (b) variasi suhu pembakaran yaitu 200oC, 300oC, dan 400oC (2) Variabel terikat : kuat lekat beton serat pasca bakar akibat penambahan variasi serat bambu. Benda uji penelitian ini adalah silinder sebanyak 64 buah dengan ukuran diameter 15 cm dan tinggi 30 cm yang ditengahnya diberi baja tulangan berdiameter 12 mm, untuk menguji kuat lekat beton serat bambu pasca bakar. Hasil penelitian sebagai berikut, (1) Adanya penambahan serat bambu berpengaruh kuat terhadap pada kuat lekat beton pasca bakar. (2) Penambahan serat bambu pada beton dengan panjang 3 cm yang dibakar pada suhu 200oC menghasilkan nilai kuat lekat tertinggi, yaitu 42,047 kg/cm2.

 

 
Sintesis Komposit Kampas Rem Bebas Asbes Berpenguat Serbuk Kulit Singkong
Authors: Primaningtyas Widya Emilia , Sakura Rahma Rei , Biqi Amir , Handoyo Chamim
Published: June 2019

An agricultural waste production in Indonesia is increasing as well as the growth of agricultural production. This has become a serious problem in Indonesia. A massive waste will have a negative impact on the health of living things. Therefore, this study aims to provide solutions for the utilization of agricultural waste for the needs of the industry in the automotive sector. In addition, the use of agricultural waste, especially cassava peel waste, can be used as a substitute for brake pads in the form of composite reinforced natural fibers. There are two conditions for cassava peel waste, carbonized and uncarbonized. 50,80,100 Mesh particle size of cassava peel powder used. The composition of the ratio of volume fraction between cassava peel powder and composite epoxy resin used are 20:80; 30:70; and 40:60. The results show that variations in the composition of fibers and resins have an impact on wear values. The best wear resistance shown from the added of 20% cassava peel powder in 100 mesh sizes of particle with 0,00061 ± 0,00039.
REMOVED: Prediksi Hambatan Kapal Ferry Ro-Ro 750 GT Berbasis Pengujian Hidrodinamika
Authors: Mujahid Ahmad Syafiul
Published: June 2019

This article was removed at the request of the authors due to developments in the reported case.  Removed article: https://doi.org/10.21070/rem.v3i2.1856Removal notice: https://doi.org/10.21070/rem.v4i2.3011
Evaluation of severity of the emotional burnout syndrome among endocrinologists
Authors: Valeeva F. V. , Khasanova K. B. , Galeeva A. T. , Kamaldinova A. R.
Published: June 2019

Purpose of the study was to study of psychocosial characteristics and prevalence of the emotional burnout syndrome among endocrinologists in the Republic of Tatarstan considering psychosocial and individual-personal factors.

Materials and methods. We studied the psychological, physical, social characteristics of the respondents using the «Emotional burnout» level method by V. V. Boiko. Our research involved 72 endocrinologists. Respondents were grouped according to the following characteristics: by place of residence, work, employment, age and experience.

Results. During the interpretation of the results we established that most of the endocrinologists had different stages of emotional burnout: stress, resistance and exhaustion. 76,4% of endocrinologists have manifestations of this syndrome. The prevalence of the formed syndrome of emotional burnout was 4,2%.

Conclusions. The prevalence of syndrome increases from the age of the doctor, the duration of employment. Doctors living in the countryside have lower emotional burnout rates than urban residents.
The problem of continuity in the provision of medical care as an element of a violation of the rights of the patient with trauma pathology
Authors: Petrovskiy E. V. , Garin L. Yu. , Tonenkova E. E.
Published: June 2019

This article is devoted to the disclosure of the key legislative problems in the implementation of the legal rights of certain categories of citizens – patients with traumatic pathology in obtaining qualified medical care. The choice of the category of patients in this work is not accidental and is due to the fact that today traumatism is one of the main causes of mortality. Disability associated with the consequences of traumatic injuries ranks third in the overall structure of the causes of persistent disability in the Russian Federation and is one of the most important indicators characterizing the quality of medical care to this population. The quality of medical care provided to the population, guaranteed by the Constitution of the Russian Federation, is affected by the observance and implementation of the rights of patients enshrined in the Federal law «on the basis of public health protection», first of all, the right to access to the required medical care. As a result of the study of this problem, a number of shortcomings of the current legal regulation of certain areas of domestic health care have been identified, which in our opinion significantly reduces the effectiveness of the state policy in the field of health protection of the population of Russia, including in ensuring the implementation of effective medical care for injuries, especially in terms of medical rehabilitation at the post-hospital stage of medical care. The methodological basis of this work was a set of methods of scientific knowledge, social processes and facts, dialectical method of knowledge, involving the study of legal and social phenomena, the method of system analysis, the method of analysis of literary, including st atistical data.
Life-threatening conditions in pericarditis of different etiologies: diagnosis and treatment
Authors: Kosonogov A. Ya. , Nemirova S. V. , Pozdishev V. I. , Nikolskiy A. B. , Kosonogov K. A. , Ribinckiy A. D. , Sidorov M. A. , Loginova S. V.
Published: June 2019

Purpose of the study: to analyze the etiology, diagnostic criteria and results of treatment of life-threatening conditions in pericarditis of different etiologies (based on our clinic materials).

Materials and methods. The study included cases of hospitalization of patients with a diagnosis of «Pericarditis» and ICD-10 codes for pericardial diseases for the period from 2009 to 2018. In the course of the work, the history and clinical picture of the disease, laboratory and radiation research methods were analyzed. All patients started treatment of the underlying disease and performed symptomatic therapy, including those aimed at restoring hemodynamics and normalizing water and electrolyte disorders, stopping inflammation and auto-aggression of the immune system. When signs of compression/cardiac tamponade were detected, pericardiocentesis was performed, according to indications, drainage/fenestration of the cardiac sac, pericardiotomy were performed. In the postoperative period was carried out antibacterial and symptomatic therapy.

Results. Life-threatening diseases of the pericardium accounted for 32,03% of all patients treated in the hospital for pericarditis. The most frequently detected signs of a hemodynamically significant compression and cardiac tamponade, less often purulent and constrictive P. Isolated 25 patients underwent closed drainage with pericardiocentesis, in 1 case the drainage was supplemented with f ibrinolytic therapy. Sanitation of the cavity and fenestration of the pericardium were carried out in 11 patients, pericardiotomy with notched drainage in 2 patients, thoracotomy with pericardiectomy – 4. In the postoperative period, the symptoms of inflammation were reduced, the level of cardiac enzymes decreased, the electrolyte balance stabilized. Most patients noted a distinct regression of the symptoms of pericarditis and cardiac compression. Recurrent P was noted in 5 cases, deaths occurred in 4 cases (8,16%).

Conclusion. Early verification of the diagnosis and timely decompression of the heart with fractional evacuation of the exudate or pericardectomy with respect to the sequence of release of the heart chambers from adhesions and adhesions against the background of complex therapy allows to achieve positive dynamics, and fenestration of the cardiac bag with the formation of a sufficiently sized opening during recurrent fluid accumulation or intrapericardial fibrin. development of severe complications of pericarditis even in patients with multiple concomitant diseases evanii and oncopathology.
Treatment of recurrent Wilms tumor: a 10-year experience of a single center in Southern China
Authors: Jiang Hong , Gao Pengfei , Chen Huadong , Zhong Zhihai , Zhang Zhichong , She Jinbiao , Liu Juncheng
Published: June 2019

Background: This study aimed to report our 10-year experiences on the treatment of recurrent Wilms tumor (WT) to improve the therapeutic outcome of recurrent WT in China. Patients and Methods: From August 2006 to August 2017, 14 patients (7 males and 7 females) with recurrent Wilms’ tumor treated at our center were included. Their medical records were reviewed.
Results: Primary WT were mainly diagnosed at the age of 1-3 years (50%). The main histology of primary WT was unclassified types (42.9%), followed by blastemal types (35.7%). Four cases did not receive standardized postoperative chemotherapy after the initial surgery. Recurrence mostly occurred within the first year after initial surgery (57.1%). The recurrent WT mainly occurred at the primary location and ipsilateral lymph nodes (35.7%), followed by extensive peritoneal metastasis (28.6%). Eleven patients underwent surgery for complete resection of the recurrent lesions. There were 9 patients achieved event-free survival for 1 year 2 months to 9 years. Three, one, one and one patients died of extensive intraperitoneal metastases, brain metastasis, peritoneal metastasis, severe intestinal obstruction vomiting, electrolyte imbalance and tumor invasion of the spinal cord, respectively.
Conclusions: Individualized multimodal treatment can effectively improve long-term survival of the patients of recurrence WT.
Choroidal thickness, ganglion cell complex and photoreceptor outer segment length evaluation in patients receiving tamoxifen therapy by spectral domain optical coherence tomography
Authors: Bolukbasi Selim , Gursel Ozge Kandemir , Cakir Akin , Erden Burak , Karatas Gamze
Published: June 2019

Background

To evaluate choroidal thickness, ganglion cell complex and photoreceptor outer segment length in patients with breast cancer undergoing tamoxifen therapy using spectral domain optical coherence tomography (SD-OCT) and to compare the results to normal eyes.

Methods

Fourty four patients with breast cancer undergoing tamoxifen therapy and fourty one healthy controls were included in this prospective, comparative study. All participants underwent a complete ophthalmologic evaluation and SD-OCT. Subfoveal, nasal (nasal distance to fovea 500 μm, 1000 μm, 1500 μm) and temporal (temporal distance to fovea 500 μm, 1000 μm, 1500 μm) choroidal thickness measurements were performed using enhanced depth imaging mode of SD-OCT. Using an Early Treatment Diagnostic Retinopathy Study (ETDRS) circle at the macular level, the automated retinal segmentation software was applied to determine thicknesses of the ganglion cell complex (GCC) by adding the macular retinal nerve fiber layer, macular ganglion cell layer, and macular internal plexiform layer parameters. The photoreceptor outer segment (PROS) length was determined by manually as the distance from inner surface of ellipsoid zone to inner surface of retina pigment epithelium after automatic retinal segmentation.

Results

The mean choroidal thickness measurements were statistically greater in tamoxifen group than controls in all quadrants (p<0.001 for all quadrants). Of all tamoxifen users (44 eyes of 44 patients), 33 eyes (75%) had uncomplicated pachychoroid (UCP). Pachychoroid pigment epitheliopathy (PPE) was detected in 5 patients (11.3%) in tamoxifen group. Patients with PPE in one eye had UCP in the fellow eye. Central serous chorioretinopathy findings were observed in one patient. Tamoxifen users had statistically lower GCC thicknesses in all inner rings of ETDRS inlay and only in nasal outer ring (p:0.027, p:0.002, p:0.002, p:0.001 and p:0.030; respectively). No statistically significant difference was found between the groups in terms of mean subfoveal PROS length.

Conclusions

SD-OCT provides valuable information in identifying the structural changes and evaluation of ocular findings in patients receiving tamoxifen therapy. Increasing choroidal thickness, PPE, thinning GCC were detected in tamoxifen users. These OCT findings may be an early indicator of retinal toxicity for patients undergoing tamoxifen therapy in follow-up period.
Protective effects of quercetin in a rodent model of anterior ischemic optic neuropathy (rAION)
Authors: Lyu Ya-nan , Min Jing-yu , Gong Yuanyuan , Gu qing , Wei fang
Published: June 2019

Background: Anterior ischemic optic neuropathy (AION) is the leading cause of sudden optic nerve-related (ON-related) vision loss in elderly people. However, no considerable treatments are available for the neuroprotection of NAION. The purpose of this study was to detect the effects of intravitreal injection of quercetin (Qcn) in a rodent model of anterior ischemic optic neuropathy (rAION).
Methods: The rAION model was established using verteporfin and laser in a photodynamic procedure on the optic discs (ON) of rats. The rats received intravitreal injection of Qcn 2 days before the injury and once/week for 4 weeks after the infarct on optic neuropathy. Flash-visual evoked potential (VEP) were recorded to assess the visual function. TUNEL and retrograde Fluorogold labeling assessed the apoptosis and density of retinal ganglion cells (RGCs). ED-1 and Iba-1 staining of the optic nerves displayed the inflammatory response.
Results: At 14 days post-infarct, Qcn treatment significantly reduced the number of apoptotic RGCs, as well as, ED1/Iba-1-positive cells/high power field(HPF) in the ON (p<0.01) as compared to the rAION group. At week 4 after rAION, 28.4% VEP amplitudes were estimated in the treated eyes of the fellow eyes in the rAION group and 64.7% in the rAION+Qcn group (p<0.01). In addition, Qcn saved the RGCs in the central retinas as compared to those of the rAION group (1967.5±162.1 and 2868±325.3 mm2, respectively (p<0.01), and the corresponding densities were 1654.8±104.8 and 2208±272.9 mm2 in the mid-peripheral retinas, respectively (p<0.01).
Conclusion: The intravitreal injection of Qcn could protect the RGCs from injury in the rAION animal model, as demonstrated anatomically by RGC density and functionally by F-VEP. Moreover, Qcn might exert an anti-apoptosis role in the survival of RGCs and anti-inflammatory in the optic nerves.
Integrative analysis of microRNA and mRNA expression in response to salt stress by UMI
Authors: Zhan Jing jing , Diao Yang yang , Zhao Yan yan , Li Chao , Han Xiao , Huang Long yu , sajjad muhammad , Wang Peng , Liu Li sen , Yan Qing di , Wei Xi , Ding Yan peng , Chu Yu , Ge xiao yang
Published: June 2019

Background

Small RNAs play an important role in regulating plant responses to abiotic stress through modulation of the processing, stability, and translation of larger RNAs. Plants employ complex mechanisms of gene regulation to respond to salinity stress.

Results

In this study, we constructed 12 small RNA libraries, 12 mRNA libraries, and a degradome library to systematically investigate the miRNAs response to salt stress. A total of 312 cotton miRNAs were identiﬁed and of these, 80 were known ghr-miRNAs. 144 genes showed significant differential expression under salt stress combined with the targeting relationship between the sRNA data and mRNA data. We found 56 miRNA-mRNA pairs which were positively correlated, and 91 pairs which were negatively correlated. Using degradome sequencing, 72 target genes were identified associated with 25 miRNA families. Gene ontology and KEGG analysis indicated some targets were involved in vital biological pathways of salinity stress tolerance: 14 were involved in responses to abiotic stress, two were associated with an environmental adaptation pathway, and a total of 16 NAC and MYB family transcription factors were related to salinity stress.

Conclusions

The present study identified a large number of cotton miRNAs and identified relationships between miRNA and mRNA, with function annotation revealing their possible biological roles in response to salt stress. Our findings will further functional studies of cotton miRNAs and the salt tolerance mechanism.
Association between periodontal disease and coronary heart disease risk in Chinese population: evidence from a meta-analysis
Authors: Cai Qing-wei , Ren Lin , Chen Rui-xin , Zou Yang , Fu Qiang , Ma Yuan-yuan
Published: June 2019

Aims

More and more research is focused on studying the relationship of periodontal disease with susceptibility to coronary heart disease (CHD), among which discrepancies have risen. The current study aimed to evaluate the possible relationship about periodontal disease and CHD in certain Chinese population.

Methods

The PubMed, Embase, Web of Science, the Cochrane Library, the Chinese Biomedical Database, and the Chinese National Knowledge Infrastructure were searched up to December 2018. The overall and subgroup analyses were performed using fixed or random-effect model depending on heterogeneity.

Results

A total of 2241 CHD cases and 2160 in 15 studies were used in the current study. Overall, a significantly elevated relationship about periodontal disease on CHD risk was found in all included Chinese subjects (OR=3.04, 95% CI, 2.37-3.92). Subgroup analyses by geographic location and sources of control were also performed; all the results in subgroup analyses were consistent with the overall result. Meanwhile, the significant association was found among the measures of periodontal disease with attachment loss, periodontal index, two or more clinical indications, and gum recession as well as CHD assessment method with WHO criteria and coronary arteriongraphy.

Conclusions

Collectively, the meta-analysis indicated that periodontal disease was capable of causing CHD susceptibility among Chinese.
Giant prolactinomas: experience of a single tertiary center in Mexico
Authors: Victoria Tania Raisha Torres , Pérez-Guzmán Mireya Citlalli , Vega-Beyhart Arturo , Coronel-Manzo Diego Armando , Martínez-Sánchez Froyland David , Pedroza Luis Tamez , Rubio Angelica Manrique , Hinojosa-Amaya José Miguel , Velarde Arturo Peña , Suarez Andres Leon , Gómez-Sámano Miguel Angel , Gomez-Perez Francisco Javier , Cuevas-Ramos Daniel
Published: June 2019

Background: Giant prolactinomas are rare tumors representing only 0.5-4.4% of pituitary adenomas, and 2-3% of prolactin secreting tumors. Clinical presentation is similar than smaller prolactinomas. However, due to the large adenoma size (≥4 cm), the normalization of prolactin levels and reduction of the tumor volume becomes a significant therapeutic challenge and multimodal treatment might be necessary.
Methods: Comparative, cross-sectional, observational, retrolective cohort, from January 1988 to December 2017. We included all patients with hyperprolactinemia, those with non-tumoral etiologies were eliminated. Our final sample consisted of 327 patients with prolactinomas. We classified them according to tumor diameter using magnetic resonance imaging (MRI), in microprolactinomas (<10mm), macroprolactinomas (≥10 mm) and giant prolactinomas with a diameter of ≥4 cm, together with prolactin level > 1000 ng/dl, and no concomitant growth hormone (GH) or adrenocorticotropic hormone (ACTH) secretion.
Results: 244 (74.6%) cases had a microprolactinoma, 72 (22%) had a macroprolactinoma, and 11 patients (3.4%) met the selection criteria for giant prolactinomas (9 males). The most common presenting features included headache, impaired vision, and erectile dysfunction. The main hormone deficiency found in men was testosterone (77.8%), followed by Thyroid-stimulating Hormone (TSH) (63%). Mean prolactin (PRL) at presentation was 2,000 ng/mL (IC 95% 1727 - 4374). All patients were treated with dopamine agonists (DA), and only 3 (27%) patients required surgery. Tumor shrinkage for giant prolactinomas with dopamine agonist was 63% on average. All patients had improved visual field defects. Since patients responded well to DA, none required further treatment modalities.
Conclusions: Giant prolactinomas are rare tumors with a male predominance. Dopamine agonists are a useful therapeutic strategy, and good response is seen with a similar average dose to those used in smaller prolactinomas. None of our patients required further medical treatment modalities although surgical debulking sometimes is necessary.
Facilitating trial recruitment: A qualitative study of patient and staff experiences of an orthopaedic trauma trial
Authors: Phelps Emma , Tutton Elizabeth , Griffin Xavier , Baird Janis
Published: June 2019

Background

Qualitative research has been used to explore patients’ and healthcare professionals’ experiences of surgical randomised controlled trials (RCTs). From this research, reasons why patients accept or decline participation and barriers to engaging clinicians in trials have been identified. In a trauma setting, recruitment to surgical trials can be particularly difficult as patients may require urgent treatment and their ability to consider their options, ask questions and reach a decision may be hindered by the impact of their injury. Little research however, has explored patients’ and healthcare professionals’ experiences of surgical RCTs in a trauma setting. This study aimed to understand participants’ and staffs’ experiences of an orthopaedic trauma trial.

Methods

We carried out semi-structured interviews with 11 participants and 24 staff (10 surgeons and 14 research associates) participating in a UK multi-centre feasibility trial comparing intramedullary nails versus distal locking plates for fractures of the distal femur (TrAFFix). Interviews explored patients’ experience of TrAFFix and their reason for participating and staffs’ experience of recruiting to TrAFFix and trauma trials more generally. Interviews were audio recorded and transcribed verbatim. Transcripts were analysed using thematic analysis.

Results

Three themes were identified. These were i) navigating research with patients after orthopaedic trauma, ii) knowing that it is the right decision and iii) making it work. These themes reflect: i) how research associates supported and guided patients through the consent process enabling them to participate, ii) the difficulty in engaging surgeons in a trial when individual equipoise and experience of the interventions is low despite the presence of community equipoise and iii) the way in which research teams worked together and encouraged the development of a research culture within the clinical teams in order to facilitate recruitment.

Conclusions

Our findings highlight the pivotal role of research associates (RAs) in facilitating trial recruitment. RAs supported patients to enable them to make a decision about participation and assisted in developing a research culture within the team by promoting studies and communicating research to clinical staff. Our findings also reinforce surgeons’ difficulty with equipoise and suggest that accepting community equipoise could facilitate recruitment.
Demokratsko školsko vođenje
Authors: Pažur Monika , Kovač Vesna
Published: June 2019

Razvoj suvremenog demokratskog društva temelji se na integriranju temeljnih demokratskih vrijednosti u sve njegove sfere i dimenzije, pa tako i u područje odgoja i obrazovanja. Ovakvi se zahtjevi stavljaju i pred škole, a pritom se ključna uloga daje ravnatelju, koji je nositelj i voditelj svake inovacije u svojoj školi (Fullan, 2005; 2007; Bush i Middlewood, 2013; Pont, Nusch i Moorman, 2008; Stein, 2015). Jedan od tipova školskog vođenja koji odgovara ovim zahtjevima naziva se demokratsko školsko vođenje, čiji razvoj s jedne strane utječe na razvoj školske kulture koja se temelji na demokratskim vrijednostima i demokratskim normama, dok s druge strane, ono omogućuje svim uključenima, učenicima i odraslima, stjecanje znanja i razvoj vještina koje će ih učiniti aktivnim građanima. Cilj ovoga rada je analizirati dosadašnje spoznaje u području specifičnog tipa školskog vođenja pod nazivom demokratsko školsko vođenje. Posebna pozornost usmjerit će se na teorijsko-praktičnu operacionalizaciju konstrukta demokratskog školskog vođenja u dosadašnjim istraživanjima. Predstavit će se i analizirati istraživanja koja nude odgovore na pitanja zašto razvijati demokratsko školsko vođenje, kako se ono može razvijati te koja je njegova uloga u razvoju demokratske školske zajednice.
Pesticide detection by a miniature microbial fuel cell under controlled operational disturbances
Authors: Chouler Jon , Di Lorenzo Mirella
Published: June 2019

Microbial fuel cell (MFC) technology holds enormous potential for inexpensive real-time and onsite testing of water sources. With the intent of defining optimal operational conditions, we investigated the effect of environmental factors (changes in temperature, pH and ionic strength), on the performance of a single chamber miniature MFC sensor. The pH of the influent had the greatest effect on the MFC performance, with a 0.531 ± 0.064 μA cm−2 current variation per unit change of pH. Within the range tested, temperature and ionic strength had only a minor impact (0.010 ± 0.001 μA °C−1 cm−2 and of 0.027 ± 0.003 μA mS−1 cm cm−2 respectively). Under controlled operational conditions, for the first time, we demonstrated the ability of this biosensor to detect one of the most commonly applied pesticides worldwide, atrazine. The sensitivity to atrazine was 1.39 ± 0.26 ppm−1 cm−2, with a detection range of 0.05–0.3 ppm. Guidelines for systematic studies of MFC biosensors for practical applications through a factorial design approach are also provided. Consequently, our work not only enforces the promise of miniature MFC biosensors for organic pollutants detection in waters, but it also provides important directions towards future investigations for infield applications.
Os topônimos na paisagem linguística da Av.Zelina em São Paulo: um encontro na interdisciplinaridade
Authors: Teis Denize Terezinha , Seide Márcia Sipavicius , Lucas Patricia
Published: June 2019

Este artigo tem por objetivo analisar, sob um viés interdisciplinar cinco nomes de lugares localizados na região da Av. Zelina a qual está localizada na região leste da cidade de São Paulo, capital do Estado de São Paulo. Na primeira seção, são apresentadas as áreas da Toponomástica e da Política Linguística, que dialogam neste artigo. Na segunda seção, os nomes são analisados como topônimos e como parte da paisagem linguística da região, esta análise é aprofundada pela utilização de resultados de pesquisas realizadas no âmbito das Ciências Humanas. Os resultados desta pesquisa evidenciam que os topônimos não são apenas parte da paisagem linguística de onde são encontrados, eles remetem à história ao prestar homenagem à etnia e à cultura daqueles que fizeram parte da história da constituição do bairro de que fazem parte, evidenciando a interdisciplinaridade entre História e Toponomástica. Eles também indicam que a paisagem linguística faz parte da paisagem cultural, resultado que aponta para as relações existentes entre Toponomástica, Política Linguística e Geografia Cultural.
O inglês como língua internacional e o papel do falante nativo: um estudo em cursos de línguas em porto alegre
Authors: Rosa Viegas Maiara
Published: June 2019

A língua inglesa é, hoje, considerada uma ferramenta do mundo globalizado, servindo para a comunicação internacional, independentemente dos seus falantes serem nativos ou não-nativos. Este trabalho objetiva analisar em que medida nove cursos de idiomas em Porto Alegre contemplam as questões do inglês como língua internacional (ILI) e qual o papel do professor falante nativo neste cenário. Para isto, diretores e coordenadores pedagógicos das escolas pesquisadas foram entrevistados, principalmente através de questionários. Os resultados mostraram que os cursos estão cientes da importância do inglês como ferramenta para a comunicação internacional, mas não demonstraram estar a par das discussões e implicações intrínsecas ao conceito de ILI. Além disso, observou-se que o mito do falante nativo parece estar enfraquecido, ao menos nas escolas de maior representatividade comercial em Porto Alegre.
Credo de Miguel Ángel Asturias: uma releitura do credo apostólico
Authors: Lage Rodrigo Conçole
Published: June 2019

O objetivo deste artigo é estudar o Credo, poema do escritor guatemalteco Miguel Ángel Asturias Rosales, em sua relação intertextual com o chamado Credo apostólico. Com essa finalidade, dividimos nosso artigo em duas partes. Na primeira, apresentamos as origens e características do texto cristão. Na segunda, após um breve comentário sobre a produção poética de Asturias, analisamos o poema visando identificar o modo como ele apresenta uma releitura política dos princípios teológicos definidos no Credo apostólico. Em anexo, apresentamos uma tradução literal do poema.
O tempo e o espaço no texto literário: perspectivas para o ensino da leitura
Authors: SOUZA ALBANYRA DOS SANTOS
Published: June 2019

Este estudo, interessado nas reflexões sobre o ensino da leitura literária e nas ideias sobre tempo e espaço, busca refletir sobre o papel do leitor na construção de sentidos do texto, através da análise da constituição espaço-temporal da obra “Barbáro” (2013), do autor/ilustrador Renato Moriconi. Para tanto, desenvolvemos uma análise interpretativista da obra, ancorada nas discursões sobre o ensino da leitura Literária (BRASIL (2006); ECO (2003); COSSON (2010)), bem como nas teorizações do Círculo de Bakhtin e de teórico contemporâneos sobre cronotopo (BAKHTIN (2014; 2018); BEMONG at al (2015); MACHADO (2010); MORSON; EMERSON (2008)). Os resultados apontam que para formar um leitor crítico e autônomo é preciso levá-lo a refletir não apenas sobre os significados do texts, como também sobre outros sentidos que somente são percebidos quando partimos da sua constituição espaço-temporal.
Formação técnica integrada:
Authors: Martins Ferreira de Souza Ednéia , Rodrigues Tognato Maria Izabel
Published: June 2019

Considerando a formação técnica integrada como modalidade, capaz de promover desenvolvimento humano e social, objetivamos discutir as relações entre o perfil e as expectativas de estudantes e as propostas de um Curso Técnico Integrado em Informática, de um campus do Instituto Federal. Para isso, utilizamos as abordagens qualitativa e quantitativa (RAMOS, 2013; CRESWELL, 2007; 2018) com questionários, registros acadêmicos e documentos institucionais como instrumentos. Para as análises, pautamos nossos estudos na Teoria da Complexidade (MORIN, 1991, 2005) e no Interacionismo Sociodiscursivo (BRONCKART, 2009; 2008; BULEA, 2010) na identificação de conteúdo temático mobilizado nas representações dos estudantes nas respostas ao questionário. Os resultados parciais deste estudo apontam para uma maior compreensão das possíveis relações entre o perfil e as expectativas dos estudantes, assim como entre estes e as propostas do contexto de formação investigado, possibilitando um debate social acerca dessa formação e suas possíveis contribuições sobre o desenvolvimento social e humano.
Jovens estudantes ligados à Universidade:
Authors: Bethencourt María Teresa , Villegas María Margarita
Published: June 2019

Neste trabalho examinamos as práticas de subjetivação inerentes ao processo de compreensão de ser um estudante universitário, vivido por jovens estudantes a carreira docente, que são narrados na universidade. Os textos (narrativas) e metatextos (entrevistas e revistas de aulas), produzidos por dez alunos de diferentes especialidades, durante o desenvolvimento de um curso oferecido em uma universidade pública venezuelana de formação de professores, constituem o corpo textual analítico coletado no contexto da pesquisa etnográfica. Seu tratamento resultou em três categorias de descobertas: a) aceitação das expectativas sociais; b) reconhecimento das virtudes da universidade e c) reconfiguração simbólica. Conclui-se que o vínculo com a universidade exige proximidade e comunhão entre os interesses pessoais e culturais, que ocorrem quando os jovens chegam a questionar-se como parte do sistema universitário e o significado que eles compartilham no campo.
Ficha individual do Aprendiz Marinheiro do no Livro de Socorros (1872-1974)
Authors: Soares Júnior Azemar dos Santos , Cury Cláudia Engler
Published: June 2019

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