bluuebunny/crossref_metadata_2025 huggingface dataset:
Review on Nanoemulsion Technology: A Formulation for Enhanced Therapeutic Efficacy
Authors: Kanawade Shubham , Jagdale Vaishnavi , Shinde Ashutosh , Poojari Divyesh , Pawar Harish
Published: March 2024

Nanoemulsions have emerged as a revolutionary technology in the realm of pharmaceutical formulations, holding immense promise to transform therapeutic outcomes. This comprehensive review delves into the intricate world of nanoemulsions, highlighting their pivotal role in advancing medication delivery systems. Researchers and pharmaceutical scientists are driven by the prospect of maximizing the efficacy of diverse medicinal compounds through the strategic incorporation of nanoemulsions. These finely tuned liquid-in-liquid dispersions, characterized by nanoscale droplets (approximately 100 nm), induce transformative effects. The resulting increase in surface area per unit volume and enhanced drug solubility pave the way for refining pharmaceutical formulations. Within this exploration, we delve into the latest advancements and methodologies shaping nanoemulsion creation. Novel strategies for precise drug delivery, heightened bioavailability, and reduced side effects are carefully examined. This review emphasizes the paramount significance of nanoemulsion technology in shaping the landscape of pharmaceutical formulations. By elevating therapeutic efficacy, nanoemulsions emerge as a critical tool for optimizing drug delivery systems, presenting a pathway to more effective and patient-friendly pharmaceutical solutions. The convergence of nanoemulsion technology and pharmaceutical innovation holds promise for advancing the future of therapeutic interventions.
The Journey of Cyrenaic Medicinal Plant Silphium: A Review
Authors: Panda Taranisen , Kumar Sahu Sarat , Apollo Master , Ballav Mohanty Raj
Published: March 2024

The paper tries to discuss the mysterious extinction of the ancient herb known to the Romans as Silphium (Greek Silphion). It was assumed that the Silphium plants became lost in the first century AD. Moreover, evidence from the literature depicts the presence of Silphion plant up to the fifth century. Silphium in classical antiquity was used for being an aphrodisiac or as medicine. A myriad of medical properties attributed to Silphium, the most renowned use in ancient times was as a contraceptive, abortifacient, for menstrual disorders and as an emmenagogue that would expel the fetus. The valuable product was the resin. It was the indispensable article of trade from the ancient North African city of ‘Cyrene’, growing abundantly in a narrow coastal tract. It was so important a plant for the people of that locality that, most of their coins bore a picture of that plant. But unfortunately, the plant became extinct due to its over-exploitation, including over-harvesting and over-grazing, compounded by changes in the local climate.
The Ratio of Key Metabolic Transcripts Is a Predictive Biomarker of Breast Cancer Metastasis to the Lung
Authors: Mathur Deepti
Published: March 2024

Breast cancer is a disease marked by cellular diversity. Primary breast tumors can spread to and colonize multiple organ sites, forming metastases. Understanding the factors that drive metastatic tropism and being able to predict metastasis to specific organs a priori remains a challenge. In this study, we investigated how rewired metabolism underlying organ-specific metastasis in breast cancer could help identify strategies to improve the treatment and prevention of metastatic disease. We found that parental breast cancer cells and metastases in the brain and lung each had a distinct, heritable metabolic flux signature. Lung metastatic cells maintained particularly high glycolytic flux by activating a pathway sink into lactate, characterized by a high ratio of lactate dehydrogenase (LDH) to pyruvate dehydrogenase (PDH) gene expression. This elevated LDH/PDH ratio also correlated with lung metastasis in patients with breast cancer. We employed feature classification models on patient data and found that expression of genes taken individually or collectively were unable to predict metastatic tropism. However, the LDH/PDH ratio was a significant predictor of metastasis to the lung specifically. Importantly, alterations of LDH/PDH in the primary tumor in cell lines and patients indicated future lung metastases, such that this ratio was a bona fide predictor. Lung metastases in pancreatic cancer models also exhibited the same metabolic flux alteration, suggesting that lactate production may be a convergent phenotype in lung metastasis across cancer types. Together, these analyses highlight the essential role that metabolism plays in organ-specific cancer metastasis and identify a putative biomarker for predicting lung metastasis in breast cancer patients.
Audit Methodology in Facing Financial Risk: Perspectives from Internal Auditors
Authors: Wijaya Erwin , Pratiwi Gina , Surya Dino , Permata Hanna , Wulandari Jihan
Published: March 2024

This study investigates the role of audit methodology in addressing financial risks from the perspectives of internal auditors. The research aims to understand the importance of risk assessment, challenges in implementing audit methodology, effectiveness of audit methodology in mitigating financial risks, and recommendations for enhancing audit methodology. Thematic analysis was employed to analyze interviews with internal auditors, revealing key themes and patterns. The findings highlight the critical role of risk assessment in audit methodology, emphasizing its significance in guiding audit planning and resource allocation. Internal auditors identified challenges such as the dynamic nature of financial risks, technological advancements, regulatory requirements, and resource constraints. Despite these challenges, auditors expressed varying levels of confidence in the effectiveness of audit methodologies, with some acknowledging limitations and areas for improvement. Recommendations for enhancing audit methodology include investing in training and development programs, leveraging technology, enhancing communication and collaboration, and fostering a culture of innovation. The study contributes to the literature by providing insights into the challenges and opportunities associated with audit methodology in mitigating financial risks, emphasizing the need for continuous adaptation and innovation. The implications extend to both theoretical and managerial domains, offering practical guidance for strengthening internal audit functions and enhancing organizational resilience against financial risks.
Evaluation of Sampling Techniques in Audit: A Qualitative Approach
Authors: Santoso Fadli , Wulandari Indarsih , Pratiwi Dinda
Published: March 2024

This study explores the evaluation of sampling techniques in audit engagements, aiming to provide insights into the factors influencing auditors' decisions and the effectiveness of different sampling methods. The research adopts a qualitative approach, conducting a comprehensive literature review to identify key themes and discussions surrounding sampling techniques in auditing. Factors such as population characteristics, audit objectives, resource constraints, audit complexity, regulatory requirements, and technological advancements are analyzed to understand their impact on sampling decisions. Through thematic analysis, the study identifies emerging themes, including the effectiveness of sampling techniques, factors influencing sampling decisions, and the role of technological advancements in audit sampling. Findings suggest that while traditional sampling methods like random sampling and systematic sampling remain prevalent, innovative approaches such as statistical sampling and probability-proportional-to-size sampling offer enhanced precision and reliability, particularly in complex audit environments. The integration of technology, particularly data analytics tools and audit software, has revolutionized audit sampling practices, enabling auditors to conduct more comprehensive and efficient sampling procedures. Overall, the study contributes to the existing body of knowledge on sampling techniques in auditing and provides practical implications for audit practitioners, researchers, and policymakers.
Audit Quality and Its Impact on Financial Reporting Transparency
Authors: Darmawan Aliya
Published: March 2024

This qualitative research study investigates the intricate relationship between audit quality and financial reporting transparency within the corporate governance landscape. Drawing on principles of grounded theory, the research aims to explore the interplay, determinants, and implications of this relationship informed by existing literature. Through systematic document analysis of academic articles, regulatory documents, and scholarly publications, key dimensions and determinants of audit quality and financial reporting transparency are identified and analyzed. The study reveals that audit quality is influenced by factors such as auditor tenure, audit firm size, auditor industry specialization, and audit fees, each playing a nuanced role in shaping the effectiveness and reliability of audits. Similarly, financial reporting transparency is influenced by regulatory frameworks, theoretical perspectives, and technological advancements, highlighting the multifaceted nature of transparency mechanisms and drivers. The findings underscore the critical role of audit quality in enhancing financial reporting transparency, emphasizing the importance of auditor independence, competence, and ethical conduct. Moreover, the study highlights the interconnectedness of audit quality, financial reporting transparency, and corporate governance, with effective governance mechanisms serving as critical determinants of both audit quality and transparency outcomes. The research contributes to the understanding of the complex dynamics shaping audit quality and financial reporting transparency, providing valuable insights for stakeholders in the auditing profession and corporate governance.
The Influence of Auditor Independence on Audit Quality: A Qualitative Research
Authors: Kurniawan Erwin
Published: March 2024

This qualitative research explores the influence of auditor independence on audit quality from diverse stakeholder perspectives within the auditing profession. The study aims to elucidate the perceptions, experiences, and challenges faced by auditors, corporate executives, and investors regarding auditor independence and its impact on audit quality. Semi-structured interviews and document analysis were employed to collect data, allowing for a comprehensive understanding of stakeholder perspectives. The findings reveal divergent viewpoints on the concept of auditor independence, with auditors emphasizing ethical principles and regulatory oversight, corporate executives highlighting the collaborative nature of the auditor-client relationship, and investors emphasizing the need for transparent financial reporting. Factors influencing auditor independence, such as auditor tenure, fee dependency, provision of non-audit services, and regulatory frameworks, were identified and discussed. Despite the complexities inherent in maintaining independence, stakeholders recognize the importance of regulatory interventions, ethical guidelines, and stakeholder engagement in safeguarding auditor independence and enhancing audit quality. Moving forward, efforts to enhance auditor independence and audit quality should prioritize regulatory reform, ethical leadership, and collaborative solutions within the auditing profession.
Public assistance, living environments, and food insecurity: A comparative community case study
Authors: Bezuneh Mesfin , Yiheyis Zelealem
Published: March 2024

Food insecurity continues to affect certain seg­ments of the U.S. population at the household and individual levels even when the economy is experi­encing growth. This recognition has led to the design and implementation of food assistance programs, such as the Supplemental Nutrition Assistance Program, targeting food hardship in low-income families. This is in addition to other types of government assistance, such as housing subsidies and public housing, as low-income households and individuals face similar challenges in housing security. Concern over “concentrated poverty” in traditional public housing environment has contributed to a shift toward mixed-income developments, envisaged to improve the living conditions and economic opportunities of public-housing residents. This paper provides a compara­tive assessment of food insecurity in traditional and mixed-income public housing communities. It also examines the effect of nonhousing public assis­tance on food insecurity and the temporal relation­ship between the timing of food hardship and the receipt of assistance. Administering a modified version of the U.S. Department of Agriculture (USDA)’s Household Food Security Module to the majority of residents in the two communities, the researchers found negligible differences in food insecurity between recipients and nonrecipients of government assistance. Nevertheless, government assistance appeared to improve the probability of being food secure as it interacted with living envi­ronments, suggestive of greater beneficial effect in the environment of mixed-income housing. The results show that the number of households experi­encing reduced food intake was lowest in the first two weeks and highest during the fourth week of the month.
Castro Marim: Where Sin Became Salt in Portugal’s Algarve, 1450–1836
Authors: Coates Timothy J. , Pieroni Geraldo
Published: March 2024

Castro Marim, in SE Portugal, was a site of internal exile for several thousand minor sinners and convicts from the 1400s until the 1830s. The punishment was revived by the Estado Novo dictatorship a century later. During early modern times, the guilty could flee to several border towns for sanctuary. The state’s courts and later courts of the Inquisition directed minor offenders to this town, typically for two to three years. These newcomers were forced to either enter the local work force or flee. Here we see a detailed example of social control and coordination between the early modern Church and state. Crime, sin, punishment, redemption, sanctuary, the Enlightenment, monopolies, and smuggling interact with this system of forced labor. Sanctuary, internal exile, and town of free people created a unique legal and social space. This labor force was long-lasting, flexible, and useful. Tax evasion and smuggling forced Lisbon to create neighboring Vila Real de Santo António, with tighter fiscal control and free labor which would eventually supersede this forced labor system in Castro Marim. Internal exile was a semi-independent judicial component linked to manpower needs overseas, ending as those demands increased.
Virginia’s Eastern Shore and Edmund Scarburgh: Indigenous Labor and the Plantation Economy in the Seventeenth Century
Authors: Shefveland Kristalyn Marie
Published: March 2024

English settler colonies introduced a new market structure to the Native peoples of the Chesapeake watershed. Alongside trade in goods, traders and merchants exchanged peoples for labor. The Eastern Shore of the Virginia colony provides an interesting case study that provides a clear picture of the importance of Native laborers alongside African and English laborers in the early plantation economy. Power dynamics in colonial Virginia were characterized by social hierarchies, economic interests, and the exercise of authority by influential individuals. By examining cases of illegal indenture and enslavement of Native peoples by Colonel Edmund Scarburgh in the 17th century, one can see that Scarburgh emerges as an unstoppable vigilante both at the time and in historical memory, because of his accumulation of wealth and power through the Indigenous slave trade as well as his transatlantic trade interests. Physically, and in many ways legally, isolated from the rest of the Virginia colony, the case study presented herein serves as a window into the power machinations and ambitions of one man and his desire to build his plantation empire unchecked by any conventions or rules of law.
Digital marketing strategies for medical products: A theoretical and practical review
Authors: Sodiq Odetunde Babatunde
Published: March 2024

Digital marketing has emerged as a crucial component in the promotion and dissemination of medical products. This theoretical and practical review delves into the strategies essential for navigating this dynamic landscape effectively. The paper begins with an exploration of the target audience, emphasizing the importance of understanding the needs and behaviors of healthcare professionals, patients, and caregivers. Subsequently, it discusses various digital marketing tactics, including content marketing, search engine optimization (SEO), social media marketing, email marketing, and influencer marketing, elucidating their roles in engaging and educating the target audience. Moreover, the review emphasizes the significance of data analytics and optimization for continuous improvement, while also highlighting the necessity of regulatory compliance and ethical considerations. Drawing upon case studies and practical examples, the paper provides insights into successful digital marketing campaigns within the medical products industry, offering valuable lessons and best practices. Ultimately, this review aims to equip stakeholders with the knowledge and strategies needed to harness the full potential of digital marketing in promoting medical products while adhering to regulatory standards and ethical principles.
MISA TRADISIONAL MENURUT MOTU PROPRIO TRADITIONES CUSTODES
Authors: Karundeng Federicoh , Dedha Fransiskus Xaverius , Oroh Aristi Vanessa
Published: March 2024

Liturgy is an expression of faith in God which is expressed in a great way through the Eucharistic Celebration. Before the Second Vatican Council, the Church celebrated the Liturgy by using the 1962 Roman Missal, or celebrating the Traditional Mass (Tridentine). After the implementation of the Second Vatican Council, it was mutually agreed that the expression of Faith through the liturgy, using the 1970 Roman Missal, which was issued by Pope Paul Vi. Since then, the practice of using traditional mass is rarely used anymore. During the Pontifical period of Pope Benedict XVI, he issued the Motu Proprio Summorum Pontificum, which permitted the Return to the Practice of this Traditional Mass. Three years later, Pope Francis asked the bishops through the Congregation for the Doctrine of the Faith to review the implementation of the Summorum Pontificum. The Pope discovered that there was a movement towards division, so Pope Francis issued the Motu Proprio Traditionis Custodes to cancel the existing norms and laws in the Summorum Pontificum, to maintain the unity of the Church.
Lactate/Albumin Ratio as a Predictor of Mortality in Patients with Crimean-Congo Hemorrhagic Fever
Authors: TEKİN Yusuf Kenan , ÇELİK Şimşek
Published: March 2024

Objective:This study aimed to determine the relationship of lactate/albumin (L/A) ratio with prognosis and fatality in CCHF patients. Materials and Methods: A total of 260 patients diagnosed with CCHF between January 2019 and December 2022, 36 of whom were deceased and 224 of whom were alive, were retrospectively included in the study. The findings of survivor and non-survivor patients were compared. Results: There was no significant difference between the groups in terms of age and gender. While albumin, glucose and platelet levels were quite low in the patient group who died due to CCHF (p
Análise espaço-temporal da leishmaniose tegumentar no estado de Goiás
Authors: Gioia Thamy Barbara , Barros Juliana Ramalho , Silva Renato Rodrigues , Rodrigues Renne , Santos Mayra Nayara Nair dos
Published: March 2024

A leishmaniose tegumentar é uma doença infecciosa com padrões epidemiológicos de transmissão relacionados a alterações significativas na paisagem, decorrentes principalmente de atividades econômicas. O objetivo deste trabalho foi analisar a disseminação dos casos de leishmaniose tegumentar no estado de Goiás entre os anos de 2001 e de 2020, buscando evidências de formação de agrupamentos regionais. Foram utilizados dados públicos disponíveis no Sistema de Informações de Agravos de Notificação (SINAN) e bases cartográficas disponíveis nas bases do Instituto Brasileiro de Geografia e Estatística (IBGE).  Para a avaliação da tendência temporal, a técnica estatística de regressão por joinpoint foi aplicada às taxas estaduais. A fim de reduzir possíveis flutuações aleatórias nas taxas de prevalência em nível municipal, recorreu-se à análise bayesiana global. As taxas ajustadas foram posteriormente aplicadas à equação de Moran, para avaliação de formações dos agrupamentos regionais. A análise de tendência temporal em nível estadual indicou redução de casos no período analisado, com variação percentual anual de -2,8 casos a cada 100.000 habitantes. Os resultados dos índices de Moran evidenciaram a formação de agrupamentos regionais. Tais regiões apresentam grupos de municípios com significativa vulnerabilidade social e exploração econômica voltada a atividades agrícolas e de mineração
Águas e lugares (in)salubres na sede municipal de Barreirinha/AM
Authors: Soares Juliana de Souza , Araújo Nelcioney José de Souza
Published: March 2024

O objetivo desta pesquisa é analisar o contexto socioambiental da sede municipal de Barreirinha - AM. Isso porque a discussão de cidade ideal sempre foi uma pauta levantada na Grécia Antiga, mas que na atualidade muitas cidades não possuem uma infraestrutura adequada. Verificou-se que em Barreirinha, o principal problema identificado é a falta de saneamento básico, o que resulta em desigualdade nos bairros da cidade. Alguns locais estão sujeitos a problemas ambientais, sanitários e de saúde, enquanto outros recebem investimentos adequados. Portanto, a sede municipal de Barreirinha ainda não pode ser considerada uma cidade justa, pois os cidadãos não têm acesso igualitário aos seus direitos. São necessárias políticas públicas para combater essas deficiências e criar uma cidade mais equitativa. Dessa forma, a pesquisa enfatiza a importância de investimentos em infraestrutura e saneamento básico para melhorar a qualidade de vida e o bem-estar dos cidadãos
Saúde e Ambiente no PROSAMIM do Alvorada na cidade de Manaus-AM
Authors: Pereira Jessica da Silva , SOARES Juliana de Souza , ARAÚJO Nelcioney José de Souza
Published: March 2024

O presente estudo tem como objetivo geral analisar a infraestrutura sanitária e ambiental do PROSAMIM do bairro Alvorada na cidade de Manaus-AM. O canal dos franceses (antigo igarapé da sapolândia) na qual entrecorta o bairro alvorada, mesmo contemplado pelo PROSAMIM, programa do Governo Estadual, atualmente ainda persiste em problemas de ordem socioambiental. Para isso, foi utilizado o estudo de caso como estratégia de interpretação da problemática apresentada na pesquisa. Os procedimentos metodológicos foram realizados em consonância aos objetivos propostos como levantamento bibliográfico, dados primários e secundários em sites institucionais, elaboração de questionários, atividade em campo que consistiu na entrevista. Percebe-se que mesmo com a implantação do PROSAMIM para aquela área, ainda existem muitas adversidades identificadas tanto de ordem social quanto ambiental. É necessário que a sociedade e as autoridades públicas despertem para a importância da conservação e recuperação desse importante recurso hídrico
Doenças relacionadas à pobreza: uma análise sobre os casos de tuberculose em São Gonçalo (RJ) entre 2010 a 2019
Authors: Carvalho Gabriela da Costa de , Ferreira Luiz Felipe Soares , Kede Maria Luiza Félix Marques
Published: March 2024

Dentre as doenças relacionadas à pobreza, a tuberculose é a mais emblemática devendo destacar que fatores sociais são determinantes para a sua disseminação e concentração.  Este artigo visa analisar a ocorrência da tuberculose no município de São Gonçalo (RJ) buscando observar sob a perspectiva da produção do espaço geográfico, a distribuição espacial da doença. Com isso, buscou-se investigar o número de casos e de incidência notificados no Sistema de Informação de Agravos de Notificação (SINAN) relacionando-os com os dados socioeconômicos do IBGE, como renda per capita, índice de Gini e escolaridade referentes ao município, além de compreender o contexto da tuberculose no Estado do Rio de Janeiro, bem como as políticas e metas de combate e controle da doença em diferentes escalas. Apesar de determinadas limitações em relação aos dados de saúde, é possível compreender que fatores como a urbanização desordenada municipal e suas consequentes situações de vulnerabilidade possuem um papel de destaque na ocorrência e persistência da tuberculose, além de favorecer a compreensão básica do efeito da relação entre o espaço geográfico com a produção das desigualdades e a ocorrência das doenças.
Qualidade do ar na cidade de Manaus: material particulado e suas relações com as queimadas
Authors: Oliveira Bruna Larissa Aires de , Souza Rodrigo Augusto Ferreira de , Andreoli Rita Valéria
Published: March 2024

A Amazônia tem enfrentado incêndios florestais com emissões de poluentes para a atmosfera, impactando na qualidade do ar e na saúde humana. Manaus se destaca como uma importante área de estudo para avaliar o impacto das queimadas na qualidade do ar. A regulamentação brasileira recomenda o limiar máximo de 25 µg/m3 (em 24h) para o Material Particulado fino (MP2.5), para que o ar seja considerado de boa qualidade. Assim, o objetivo deste trabalho foi estudar a variabilidade temporal do MP2.5 na atmosfera de Manaus, durante o período de 2003 a 2021, a fim de verificar se os níveis de poluição do ar estavam dentro dos limites recomendados. Os dados foram avaliados utilizando análises de diagramas de caixa, considerando o período total do estudo como referência, para avaliar dois períodos de distanciamento social para o combate a COVID-19. Os resultados mostram que o MP2.5 apresenta um ciclo anual bem definido, com concentrações menores do que 25µg/m^3 no período chuvoso. No período seco, as concentrações de MP2.5 atingem valores superiores ao máximo recomendado. Durante isolamento social foi possível observar uma diminuição na concentração média mensal, que pode estar associada à diminuição das atividades industriais e a redução na mobilidade urbana
The Impact of Achievement Orientation on Goal Clarity
Authors: Taridi Muhamad , Noviriani  , Asy'ari Su'aidi
Published: March 2024

Purpose: This study is to enrich the scientific paradigm in the field of Islamic education management, and to explore the effect of achievement-oriented leadership style on the goal clarity, particularly the study of organizational behavior.
Study design/methodology/approach: This study employs a quantitative research approach using the survey method. The population consists of all teachers employed in a private Islamic high school in one of the provinces in Indonesia. The sample size was determined to be 120 in number, selected through the area sampling technique. Data collection utilized a questionnaire featuring a Likert scale as the primary instrument.
Findings: It revealed that being achievement-oriented has a direct positive impact on goal clarity. The conclusion of this study is that the achievement-oriented, approach influences the goal clarity of Islamic Private High School in one of the provinces in Indonesia.
Originality/value: In light of these criteria, the observed t-value (11.11) surpasses the tabulated t-value (1.98), leading to the rejection of the null hypothesis (H0) and acceptance of the alternative hypothesis (H1). The research hypothesis asserts a direct influence of achievement-oriented heads of Islamic Private High School (X1) on the goal clarity of Islamic Private High School (X2), which is supported by the evidence.
Use of vegetable oils in wound treatment
Authors: Bizinoto Lara Bernardes , Soares Fernanda de Oliveira , Quadros Elza Alice de , Rosado Isabel Rodrigues , Martin Ian , Rezende Rodrigo Supranzetti de , Rosado Sara Rodrigues , Sampaio Renato Linhares , Alves Endrigo Gabellini Leonel
Published: March 2024

This study addresses the use of vegetable oils in wound treatment. These oils contain bioactive compounds that confer analgesic, antiseptic, soothing, healing, and emollient properties. Notably, candeia oil is recognized for its anti-inflammatory and antimicrobial properties, while grape seed oil is rich in proanthocyanidins with potent antioxidant activity. Lavender oil, in addition to stimulating cell proliferation and neovascularization, possesses antioxidant and antibacterial properties. Pumpkin seed oil, on the other hand, is rich in fatty acids and lipids, which help combat oxidative stress in wounds. Coconut oil, with its antibacterial and antifungal properties, and copaiba oil, with anti-inflammatory and healing actions, are also highlighted. Cucumber seed oil, besides its antioxidant properties, exhibits antimicrobial activity due to the presence of oleic acid. Lastly, tea tree oil, known for its antimicrobial action, also promotes wound healing. These oils represent a promising and natural alternative in wound treatment, although further studies are needed to determine their dosages and ensure their clinical safety.
María José Barros Cruz. 2023. La música de Ana Tijoux. Activismo, nuevas solidaridades y voces de la calle (Chile 1997 2020). Santiago: Fondo de Cultura Económica, 138 pp.
Authors: Godoy Marqués Tomás
Published: March 2024

Ana Tijoux es probablemente la rapera chilena más conocida internacionalmente producto de su larga trayectoria musical, al igual que sus constantes apoyos a causas políticas y sociales En este sentido, era de esperar que en algún momento los /as investigadores/as se interesarían por analizar los impactos de sus letras , videos y trayectoria . De esta forma se presenta el libro La música de Ana Tijoux. Activismo, nuevas solidaridades y voces de la calle (Chile 1997 2020)2020), de la Doctora en Literatura por la Pontificia Universidad Católica de Chile María José Barros Cruz. A través de su e nsayo, la autora, en un ejercicio reflexivo , crítico y también desde una posición transparente de su gusto musical, analiza la música de Ana Tijoux, su trayectoria y la forma en que ha articulado su posición de rapera.

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Relato y música-fusión diaguita para un nuevo imaginario
Authors: Céspedes Alfaro Ana
Published: March 2024

El presente artículo describe y analiza los discursos y performances de cinco artistas de la región de Coquimbo, Chile, quienes a través de sus propuestas performáticas fusionan distintos géneros musicales con la raíz diaguita. El objetivo es conocer cuáles son los elementos que sustentan esta raíz y cuál es el imaginario que han creado sobre esta cultura El contexto de análisis está estrechamente relacionado con la música popular y los géneros fusión. Así, esta investigación se elaboró desde una perspectiva etnomusicológica, utilizando el método etnográfico y técnicas como la observación participante y entrevistas a músicos del norte semiárido de Chile, mismo lugar que históricamente ha ocupado el pueblo D iaguita . Se desprende que existe una crecie nte necesidad de revindicar las raíces diaguita en un país que vive profundos cambios estructurales y cuyos pueblos originarios han estado ausentes de la historia republicana oficial. En la actualidad, algunos intérpretes de esta región, adoptan una estética visual y sonora manifestada en el uso de diseños, colores, instrumentos musicales y sonidos , para sustentar sus fusiones y crear nuevos imaginarios.
¡Zúmbale primo! El estilo “ranchero-tropical” en la actualidad mapuche
Authors: Catrileo Pablo
Published: March 2024

El pueblo-nación mapuche cruza fronteras e identidades. Su territorio ancestral, denominado Wallmapu, atraviesa las barreras nacionales de Chile y Argentina. Este trabajo ofrece una aproximación hacia la forma en que el cancionero mexicano, allegado al Cono Sur hace poco más de un siglo, ha permeado esta sociedad indígena. La llamada música ranchera, por años ha gozado de arraigo dentro de las comunidades mapuche, a tal punto que hoy, sus estéticas y sonoridades han dado paso a un nuevo género en el territorio, denominado “cumbia ranchero-tropical”, ritmo híbrido que recoge herencias del corrido mexicano, la canción ranchera y la música caribeña, contando con una amplia difusión comunicacional e importante número de cultores y eventos asociados. Se trata de una reciente escena musical, la que, sin desestimar sus aportes en la dimensión festiva mapuche, ha comenzado además a incorporar discursos reivindicativos asociados a las controversias históricas con el Estado y los grupos de poderío económico, logrando además una interesante presencia trasandina de aún insospechados alcances.
Job Satisfaction in Education Sector of Megacities: A Study of Higher Secondary Institutions of Karachi
Authors: Warda Hussaini  , Dr. Mustafa Hyder  , Syeda Ghanwa Hussaini
Published: March 2024

Megacities have been centering of attraction for their modernity, growth and opportunities, whereas they combat with number of challenges like overcrowding, high cost of living, increased competition etc. Similarly, megacity Karachi (biggest metropolitan city of Pakistan, ranked as 7th most populous city in the world, with the growth rate of 2.41%, 2020), which makes it quite apparent that managing in this mega city do makes it challenging on individual level as well. Every megacity depends upon industries and organizations for its growth and Education sector is one of those key players, where Higher Secondary Education Institutions are considered as backbone in employing more of skilled workers. Job satisfaction is the main predictor of organizational success. This paper examined the factors affecting the job satisfaction in Higher Secondary Educational Institutions of Karachi. The data were collected through primary data gathering using questionnaire for employees working in public and private colleges of megacity Karachi. Sample size is restricted to 100 respondents selected through convenient sampling. This research was aimed at finding relationship between employees’ job satisfaction in Higher Secondary Education Institution of Megacity (Karachi) and its dynamics. In final part of this research, we tried to find out relationship between level of job satisfaction and demands of the megacity, exploring factors affecting job satisfaction in megacities.
Prevalencia y severidad de los síntomas de la menopausia en mujeres mayores de 60 años
Authors: Espitia de la Hoz Franklin
Published: March 2024

Contexto: los síntomas de la menopausia pueden ser tan severos o prolongados en el tiempo, con la posibilidad de afectar la calidad de vida de las mujeres que los padecen.
Objetivo: determinar la prevalencia y la severidad de los síntomas de la menopausia en mujeres de 60 años o más, y conocer los factores de riesgo asociados.
Metodología: estudio de corte transversal con una muestra de 117 mujeres de 60 años o más con útero intacto y sintomatología menopaúsica, residentes en Quindío, Colombia, entre 2017 y 2023. Se evaluó la calidad de vida con el instrumento Menopause Rating Scale (MRS) y se hizo un análisis descriptivo.
Resultados: la edad promedio de las mujeres fue de 67,53 ± 8,24 años; en el total de las participantes, la prevalencia de sintomatología de la menopausia fue del 9,87?%, predominado los sofocos/bochornos (80,34?%). En la escala MRS, el dominio urogenital reportó el mayor impacto en la severidad de la sintomatología (promedio: 8,94 ± 2,07 puntos) y la sequedad vaginal fue la queja más frecuente (58,97?%). Entre los factores asociados destacan la menopausia precoz (OR: 3,87; IC 95?%: 1,81-8,33) y el tabaquismo (OR: 2,97; IC 95?%: 1,44-6,31). La mayor escolaridad (OR: 0,34; IC 95?%: 0,16-0,91) mostró ser un factor protector. El 27,35?% del total de las participantes arrojó una puntuación ? 16 (severa) en la intensidad de la sintomatología según la escala MRS, lo que es compatible con la necesidad de tratamiento. La eficiencia laboral se afectó de forma severa en el 20,51?% de las mujeres, seguida de las responsabilidades del hogar con el 15,38?%.
Conclusiones: los síntomas de la menopausia pueden hacerse presentes en mujeres de 60 años o más, siendo descritos por la décima parte de las residentes del departamento del Quindío.
Desafios e oportunidades: a adoção de tecnologias na educação e os obstáculos enfrentados pelos professores na era digital
Authors: Santos Silvana Maria Aparecida Viana , Oliveira Danielle Viviane de , Dantas Junior Francisco Elzevir , Silva Glyciane Vieira da , Demuner Jocelino Antônio , Silva Kleber Kroll de Azevedo , Silva Ludimila Fernandes da , Silva Marcos Adriano Marques
Published: March 2024

Este trabalho investigou os desafios e oportunidades associados à adoção de tecnologias educacionais e os obstáculos enfrentados pelos professores na era digital. O objetivo geral foi analisar como a integração das tecnologias digitais no ambiente educacional pode transformar o ensino e a aprendizagem, destacando tanto as barreiras quanto as possibilidades criadas por essa integração. Utilizou-se a metodologia de revisão bibliográfica, examinando estudos e publicações relevantes para compilar um panorama atualizado sobre o tema. Os resultados indicaram que, apesar dos desafios técnicos, infraestruturais e de resistência à mudança por parte dos educadores, existem oportunidades significativas para a personalização da aprendizagem, ampliação do acesso ao conhecimento e fomento à colaboração e aprendizado ativo. As considerações finais ressaltaram a necessidade de investimentos em infraestrutura, formação docente e desenvolvimento de práticas pedagógicas inovadoras como caminhos para superar os obstáculos e maximizar o potencial das tecnologias educacionais.
Estratégias de design thinking: enriquecendo o aprendizado de estudantes autistas
Authors: Santos Domingos Sávio dos , Polizello Ângela Aparecida de Assis , Barros Ayrla Morganna Rodrigues , Marques Carolina Dutra , Cardoso Cezar Vasconcellos Sanfim , Ribeiro Helena Maria , Almeida Maria Rita Fialho de , Moura Tássia Laine Ferreira
Published: March 2024

O artigo oferece uma revisão abrangente sobre a aplicação do Design Thinking na educação de alunos autistas, destacando seu potencial para desenvolver habilidades cognitivas e sociais nesse grupo específico de estudantes. A análise se concentra em adaptar as estratégias centrais do Design Thinking, como visualização de conceitos, prototipagem rápida e feedback iterativo, para atender às necessidades de aprendizagem dos alunos autistas. Ao examinar práticas de ensino existentes, o estudo propõe adaptações específicas dentro do contexto do Design Thinking, visando criar um ambiente de aprendizado mais inclusivo e eficaz para esses alunos. O método adotado envolve uma cuidadosa análise das necessidades educacionais dos alunos autistas e a proposição de ajustes que valorizem suas habilidades únicas. Conclui-se que o Design Thinking, por sua abordagem centrada no ser humano e flexibilidade, é altamente eficaz para alunos autistas. Sua capacidade de personalizar o ensino e desenvolver habilidades cruciais torna-o uma ferramenta valiosa para educadores que buscam atender às necessidades diversificadas de seus alunos. Além disso, o estudo destaca que o Design Thinking não apenas aborda as necessidades educacionais específicas dos alunos autistas, mas também reconhece e valoriza suas habilidades e perspectivas singulares. Isso contribui significativamente para uma educação mais inclusiva e empática, onde cada aluno é visto como um indivíduo único com potencial para contribuir de maneira significativa para a comunidade educacional. Portanto, o artigo ressalta o papel transformador do Design Thinking na educação de alunos autistas, oferecendo uma abordagem inovadora e compassiva que promove o desenvolvimento holístico desses estudantes, ao mesmo tempo em que fortalece a cultura da inclusão e diversidade nas instituições educacionais.
It’s Time we Get Rid of Jury Trials
Authors:   University of Alabama in Huntsville, 301 Sparkman Drive, Huntsville, AL 35899., Jaiswal Sandeep S.
Published: March 2024

This paper shows that the process of jury trails are not needed in a modern society as the trial by a judge is more than enough to meet the tenets of the justice system of a fair, just, balanced, unbiased and impartial trial. We need to totally and completely abolish this giant elephant in the room from medieval ages and make the judicial process more efficient, better and quicker by introducing the trial by single judge as a norm.
ASSESSMENT OF ANTERIOR CHAMBER ANGLE ON ANTERIOR SEGMENT OPTICAL COHERENCE TOMOGRAPHY IN PATIENTS WITH ANGLE CLOSURE GLAUCOMA AND ANGLE CLOSURE SUSPECTS
Authors: Bhutto SA , LEGHARI AA , KATPAR NA , GOPANG Z , SHAIKH DYD , GUL PA
Published: March 2024

The objective of this cross-sectional study was to determine the anterior chamber angle using anterior segment optical coherence tomography (AS-OCT) in patients diagnosed with angle closure glaucoma and angle closure suspects. The research was conducted at Shaheed Mohtarma Benazir Bhutto Medical University Larkana, spanning from March 3, 2022, to June 30, 2023. Patients meeting the inclusion criteria and diagnosed with primary angle-closure glaucoma (PACG) were enrolled in the study after obtaining informed consent. The procedure, risks, and benefits of the study were explained to the patients before obtaining consent. AS-OCT was utilized to evaluate patients suspected of primary angle closure and those with confirmed primary angle closure. The results revealed a mean age of 56.21 ± 12.31 years among the study participants, with a confidence interval of 55.04 to 57.38. The mean duration of primary angle closure glaucoma was 22.52 ± 10.98 months, with a confidence interval of 21.47 to 23.57. Of the 423 patients included in the study, 219 (52%) were male, and 204 (48%) were female. Primary angle closure suspect and primary angle closure were observed in 47 (11%) and 44 (10%) patients, respectively. In conclusion, older age, higher central corneal thickness (CCT), and shorter axial length or presence of hyperopia were identified as important independent predictors of suspicion of primary angle closure and primary angle closure. These findings underscore the significance of thorough assessment and monitoring of these parameters in patients at risk of angle closure glaucoma.
Safeguarding Financial Integrity with Interval-Valued Neutrosophic Analytic Hierarchy Process for Sustainable Accounting Systems
Authors:   Accounting Program, Applied College at Muhyle, King Khalid University, Kingdom of Saudi Arabia, Adeeb Adeeb
Published: March 2024

Nowadays, financial integrity within sustainable accounting systems is critical endeavor in ensuring intricate landscape of sustainable finance. Detection of financial fraud within sustainable accounting systems is crucial for upholding environmental, social, and governance (ESG) standards and sustaining the integrity of financial practices. Leveraging advanced AI-driven technologies, these systems can effectively analyze abundance of financial data to detect suspicious patterns and anomalies indicative of fraudulent activities. Incorporating Neutrosophic logic into sustainable accounting systems improves the efficiency of financial fraud detection by accommodating inherent uncertainty in complex financial data. By leveraging this ground-breaking technology, organizations can effectively navigate the complex financial landscape while ensuring the integrity of their accounting practices. Neutrosophic logic facilitates the modelling of contradictory and ambiguous information, enabling more nuanced detection and analysis of fraudulent activities that may remain unnoticed. This study develops an automated financial fraud detection using improved sparrow search algorithm with Interval-Valued Neutrosophic Analytic Hierarchy Process (ISSA-IVNAHP) technique. The ISSA-IVNAHP technique aims to protect financial integrity via the identification of financial frauds in Sustainable Accounting Systems. The ISSA-IVNAHP technique incorporates a two-stage process. Initially, the ISSA-IVNAHP method designs ISSA-based feature subset selection approach for the optimal feature selection. Next, in the second stage, the ISSA-IVNAHP technique uses IVNAHP technique for decision-making process that enables to detection of the presence and absence of financial fraud. The simulation results of the ISSA-IVNAHP technique can be examined on financial fraud database. The experimental values reported that the ISSA-IVNAHP methodology attains maximum effeciency over other models
Mosque Management Revitalization Through Economic Empowerment of Ummah
Authors: Arifin Moh. , Muhtadi Ridan , Bawana Tate Agape
Published: March 2024

This study aims to enhance the role of the mosque's function as a religious institution so that it is not only used for the spiritual welfare of the community but also must be able to prosper economically. This study adopts a qualitative approach with the phenomenology study method and combines analysis techniques of reduction, display, and verification. The object of this research is the Jenderal Sudirman mosque, Surabaya, where the collection of data comes from observation, in-depth interviews, and documentation. The results of the study show that the application of inputs (institutional, leadership, and goals), processes (spiritual formation, personal mental formation, capacity building, and empowerment), outputs (strengthening of character, strengthening of emotional relationships, strengthening of business and strengthening of the economy and outcomes ( spiritual ability and financial ability)) in economic empowerment is still suboptimal. Therefore, mosques need to revitalize their management to collaborate with the government, state or private universities, private institutions or institutions, and the community. Moreover, the mosque should not only be prospered by the ummah; conversely, it can also prosper the ummah.
Tacrolimus-induced leukopenia in a kidney transplant recipient: A case study
Authors: Rios Ian P. , Mead Daniel R.
Published: March 2024

Introduction: Leukopenia occurs in 10%-55% of patients after kidney transplant and neutropenia occurs in approximately 28% of patients after kidney transplant. Resolution of leukopenia and neutropenia is done through treatment of the pathogen, such as cytomegalovirus, or removing the offending medication. Medications that are first thought to contribute to leukopenia include Valganciclovir, Sulfamethoxazole-Trimethoprim, and Mycophenolic Acid. Tacrolimus rarely contributes to leukopenia and neutropenia post kidney transplantation.Case presentation: This case study presents a patient who developed leukopenia and neutropenia 13 weeks after solitary kidney transplantation.Management: Mycophenolate Mofetil, Valganciclovir, Ergocalciferol, Aspirin, Famotidine, and Sulfamethoxazole-Trimethoprim were all discontinued. Filgrastim was used intermittently to increase white blood cell count. Ultimately, Tacrolimus was switched to Cyclosporine.Outcome: Leukopenia was resolved by switching Tacrolimus to Cyclosporine-based immunosuppression.Discussion: A systematic approach should be taken to resolve leukopenia post-kidney transplant. When a kidney transplant recipient is on Tacrolimus-based immunosuppression, Tacrolimus should be the last medication changed when attempting to resolve leukopenia.
On the (1/2,+)-caloric capacity of Cantor sets
Authors: Hernández Joan
Published: March 2024

In the present paper we characterize the (1/2,+)-caloric capacity (associated with the 1/2-fractional heat equation) of the usual corner-like Cantor set of \(\mathbb{R}^{n+1}\). The results obtained for the latter are analogous to those found for Newtonian capacity. Moreover, we also characterize the BMO and Lip\(_\alpha\) variants (\(0<\alpha<1\)) of the 1/2-caloric capacity in terms of the Hausdorff contents \(H^n_\infty\) and \(H^{n+\alpha}_\infty\) respectively.