bluuebunny/crossref_metadata_2025 huggingface dataset:
MRI of subcutaneous granuloma annulare: A series of four cases
Authors: Jug Liona , Rupreht Mitja
Published: February 2023

Background: Subcutaneous granuloma annulare (SGA) is a rare benign soft tissue mass that occurs mostly in the lower limbs of young children. Detailed knowledge of imaging findings is needed to avoid unnecessary invasive diagnostic procedures.

Materials and Methods: One follow-up case and three companion cases are presented. All children were between the ages of 5 and 10 years.

Results: The MRI findings demonstrated ill-defined subcutaneous masses in three cases while in one case the mass was mildly hypointense and heterogeneous on fluid-sensitive sequences. Contrast agent was administered intravenously only in one case, where moderate enhancement was observed.

Conclusion: Detailed clinical description of the lesion location was crucial. In addition, knowledge of MR imaging findings was necessary for a correct diagnosis to reassure the parents and avoid unnecessary invasive diagnostic procedures.
Drug interactions with angiotensin-converting enzyme inhibitors
Authors: Pal Marjetka , Ferk Polonca
Published: February 2023

We reviewed potentially clinically significant drug–drug interactions (DDIs) with angiotensin-converting enzyme inhibitors (ACEIs) using Stockley’s Drug Interactions books and two online DDI databases. We identified >10 such DDIs and described their mechanisms, clinical evidence and importance, as well as their management. Most DDIs with ACEIs were pharmacodynamic; only a few were pharmacokinetic. Most DDIs with ACEIs involved drugs that can lead to excessive reduction of blood pressure, hyperkalemia and impaired renal function. There is some evidence linking ACEIs with the induction of lithium toxicity. Severe hypersensitivity reactions may occur in patients treated with ACEIs with concomitant use of allopurinol or parenteral applications of iron. ACEIs should be combined carefully with hepatotoxic drugs due to their own potential hepatotoxic effects. The prevalence of adverse drug reactions due to DDIs might be high because they are prescribed frequently. Fortunately, most of such DDIs can be managed by clinical and laboratory monitoring of patients or by dosage adjustments of concomitantly used drugs.
Role of synbiotics in reducing postoperative infections in patients with hip fracture: pilot study
Authors: Pevec Teodor
Published: February 2023

Purpose: Despite the development of surgical methods, infections continue to be serious postoperative complications. Probiotics have been shown to be effective in reducing the prevalence of infections. We explored the effectiveness of probiotics in reducing the prevalence of infections in subjects undergoing surgery for hip fractures.

Methods: Fifty-one patients admitted for surgical treatment of hip fractures were divided randomly into two groups: Synbiotic 2000 Forte and placebo. The occurrence of infection was closely observed upon hospital admission until the fifth postoperative day using, among other parameters, the C-reactive protein (CRP) level. Additionally, the patients’ tolerance to Synbiotic 2000 Forte was established using subjective (self-reported problems) and objective means.

Results: Infection was confirmed in 4 patients in each group. Urinary tract infection was noted in 7 subjects and a local wound infection in 1 patient. No differences were found in CRP levels upon hospital admission and the fifth postoperative day. Tolerance to Synbiotic 2000 Forte was lower in patients undergoing placebo treatment.

Conclusion: Synbiotic 2000 Forte did not reduce the number of postoperative infections. Further studies are needed to confirm these findings.
Open-Source Software in Medical Imaging: Case-Based Study with Interdisciplinary Innovative Product Design
Authors: Harih Gregor , Čretnik Andrej
Published: February 2023

Purpose: Recently, comprehensive open-source software (OSS) solutions for medical images have been developed. They offer powerful tools for the management, visualization, storage and analysis of images. The purpose of the present study was to present the features and use of OSS in comparison with commercial software solutions when evaluating medical images.

Methods: A case study of the development of a tool handle of optimal size and shape using the free OSS “3D Slicer” is presented. Many authors recommend cylindrical-shaped handles to increase comfort, performance and to avoid cumulative trauma, but none have considered the optimal shape of the handle. Hence, we derived a method for obtainingan optimally shaped tool handle based on the power grip hand posture and non-deformed soft tissue. During magnetic resonance imaging (MRI), an outer hand mold was used to maintain the optimal hand posture. 3D Slicer was used for segmentation and 3D reconstruction of MRI. A three-dimensional (3D) hand model was exported to a commercial program for computer-aided design for the optimal tool handle.

Results: Measurements of the diameters on 3D reconstruction showed that the position of fingers wasere withheld within small deviations, which maximized maximum finger force exertion. An optimally shaped handle this way provided 25% higher contact area compared with the optimal cylindrical handle. It therefore reduced contact pressure, increased performance and comfort and could probably prevent disorders due to cumulative trauma.

Conclusion: This case study supported the use of OSS for medical imaging as a powerful and (mostly) free tool comparable with (usually expensive) commercial solutions.
Is Homeopathy related to Chemical Thermodynamics?
Authors: Drofenik Mihael
Published: February 2023

In the present article, biochemical equilibrium is used as a starting point for the application of the Le Chatelier–Broun principle in order to clarify mechanisms of homeopathic treatment. The application of chemical thermodynamics to the main homeopathic principles elucidates the well–known “Law of Similars”. In addition, the theory of intensive dilution of homeopathic remedies is discussed.
Surgical treatment of acute patellar dislocation associated with bony avulsion in children
Authors: Fokter Samo K. , Dovnik Andraž , Fokter Dovnik Nina
Published: February 2023

Purpose: The management of acute patellar dislocation in children and adolescents is controversial. Traditionally, most first–time traumatic patellar dislocations have been treated nonoperatively. However, due to new knowledge about medial patellar stabilizers some authors have advocated for surgical repair. The present report describes the mid–term subjective and functional results of operative treatment of acute patellar dislocation in children less than eighteen years of age with concomitant osteochondral fracture.

Methods: Data on a cohort of sixteen patients (eight girls and eight boys) aged 14.9 years (mean, range 12–17 years) with acute patellar dislocation were retrospectively collected. Intraarticular fragments were detected in all patients in conventional radiographs. Operative treatment consisted of arthroscopic removal (12 cases) or refixation (4 cases) of the osteochondral fragments and direct repair of the damaged medial patellofemoral ligament (MPFL) if that was still feasible (13 cases). All patients were seen at six months, and a telephone interview with twelve patients (75%) was conducted at four years (mean, range 2–7 years).

Results: Of the sixteen patients, two (12.5%) had a recurrent patellar luxation. The subjective IKDC score at the time of the most recent follow–up was 86 (mean, range 63–100), and the Marx Activity Rating Scale score was 9.2 (mean, range 2–16).

Conclusions: Direct surgical repair of the injured MPFL may be considered an option to prevent subsequent dislocation and subluxation in first–time traumatic dislocation of the patella in children and adolescents with osteochondral fractures and substantial disruption of medial patellar stabilizers.
Increased adherence to treatment guidelines for lower urinary tract infections in out–of–hours primary care settings following a simple intervention strategy
Authors: Klemenc–Ketiš Zalika , Kersnik Janko
Published: February 2023

Aim: The aim of this study was to determine whether a simple intervention could foster adherence to treatment guidelines in women with uncomplicated lower urinary tract infections (LUTIs) in after–hours primary care settings.

Methods: This was a cluster, randomised, prospective intervention study in female patients conducted in 20 out–of–hours primary care (OOHC) settings in Slovenia (10 in the intervention group and 10 in the control group). In each OOHC centre, we included 10 consecutive patients with LUTIs who sought evaluation by a physician, called in for advice, or called in for a home visit. The OOHC centres in the intervention group received a poster with a schematic presentation of LUTI treatment  treatment guidelines, which was displayed on the wall in the OHC practice.

Results: Of 20 OOHC centres, 14 were willing to participate in the study (seven in the intervention group and seven in the control group). The final sample consisted of 118 (59.0%) female patients (64 in the intervention group and 54 in the control group). The mean age of the sample was 43.2 ± 17.3 years (40.2 ± 16.4 years in the intervention group and 46.7 ± 17.8 years in the control group). Adherence to guidelines was confirmed in 42 patients (32 in the intervention group and 10 in the control group; p = 0.004).

Conclusions: A simple intervention can significantly enhance the adherence to treatment guidelines in patients with LUTIs managed in an OOHC centre.
Spectral domain optical coherence tomography for detecting glaucoma
Authors: Vrzel Dejan , Gračner Tomaž
Published: February 2023

Purpose: To evaluate the diagnostic ability of macular thickness parameters and peripapillary retinal nerve fiber layer (RNFL) thickness parameters for detecting glaucoma using spectral domain optical coherence tomography (SD–OCT).

Methods: 37 eyes of 20 glaucoma patients and 30 eyes of 16 healthy subjects included in this study underwent macular and peripapillary RNFL scans with SD–OCT using standard scanning parameters. The ”Macular Cube 512x128” scan protocol was used to measure the macular thickness. The ”Optic Disc Cube 200x200” scan protocol was used for assessing the peripapillary region. The discrimination power of all parameters for detecting glaucoma was determined by the Area under Receiver Operating Characteristics (AROC) curve and sensitivity at fixed specificity, followed by a comparison of the best macular thickness and peripapillary RNFL thickness parameters.

Results: Significant differences between glaucoma patients and healthy subjects were found in all peripapillary RNFL thickness parameters and all macular thickness parameters, except in the fovea (p=0.322). The largest AROC with sensitivity at >90% specificity among the peripapillary RNFL thickness parameters was found for the average peripapillary RNFL thickness (AROC 0.95, sensitivity 76%). The largest AROC with sensitivity at >90% specificity among the macular parameters was found for the inferior inner macular thickness (AROC 0.90, sensitivity 78%). There was no statistically significant difference between the AROCs of these two parameters (p=0.208).

Conclusion: To discriminate glaucoma patients from healthy subjects using SD–OCT, macular thickness parameters had high diagnostic ability which was comparable to that of the peripapillary RNFL thickness parameters.
“Motoso y terruco”: ideologías lingüísticas y racialización en la política peruana
Authors: Zavala Virginia , Almeida Claudia
Published: February 2023

En este artículo, analizamos usos de “motoso” y de “motoso terruco” en la política peruana, producidos en redes sociales (Twitter y Facebook), que dan cuenta de un proceso semiótico de inversión indexical en el funcionamiento de la ideología lingüística del motoseo. En este contexto, el habla “motosa” ya no se refiere a formas concretas de habla que se asocian a un grupo social, sino a prácticas y a discursos que producen un conocimiento metapragmático de cómo los “indios” supuestamente hablan o deberían hablar. La reinvención del “motoso” en articulación con “terruco” estaría revelando nuevas dinámicas en la forma como funciona el racismo cultural en el Perú. Específicamente, emerge como una estrategia para racializar, reubicar y, sobre todo, callar a personajes de la política que son vistos como potenciales amenazas a un orden social imperante de carácter colonial y neoliberal.
Ironía y creatividad léxica durante la pandemia del coronavirus
Authors: Rodríguez González Félix
Published: February 2023

El propósito de este artículo es examinar algunos de los repentinos cambios registrados en el léxico español europeo en tiempos recientes, especialmente durante la pandemia del coronavirus. Debido a las fuertes vivencias durante el periodo del confinamiento, los procesos lingüísticos tienen un carácter emocional y un tinte político muy marcados, y responden a motivaciones semánticas y morfológicas. Por un lado, sobresalen recursos habituales en la retórica política como son el eufemismo y sobre todo el disfemismo, que por vía metafórica propende a la ironía y el humor. Por el lado de la morfología, y encaminados a ese mismo fin, destacan los “cruces léxicos”, y las distorsiones y creaciones léxicas a partir de siglas.
La fuente escrita como elemento corroborativo de los cambios fónicos: evidencia onomástica
Authors: Cerrón-Palomino Rodolfo , Cangahuala Castro Sergio
Published: February 2023

La etimología científica, en contraposición a la ingenua o a la puramente impresionista, encuentra su más sólido respaldo en la lingüística histórica; y, en esta, en su conquista de la regularidad del cambio fonético. Y es que en virtud de dicho atributo el investigador, en este caso el etimólogo, puede no solo dar con el étimo de un término del cual no estaba seguro, sino que, apoyado en la regularidad del cambio, puede predecirlo, sobreponiéndose incluso ante la ausencia del corpus corroborativo disponible a la mano. El material confirmativo de una proyección etimológica puede encontrarse, sea con el descubrimiento de formas dialectales novedosas no entrevistas previamente o también en virtud de la evidencia insospechada aportada por el registro escrito filológicamente interpretado. La presente exposición procede en el siguiente orden: luego de una introducción general sobre el desarrollo de la lingüística histórica en el área andina, centramos nuestra discusión en el cambio fónico regular y su carácter predictivo en los estudios de lingüística andina con evidencias corroborativas tanto de naturaleza dialectal como documental (impresa), para luego, en una cuarta instancia, aportar testimonio manuscrito novedoso y revelador. La evidencia documental impresa o inédita gira en torno a la etimología de términos onomásticos como el de , título nobiliario, y el de , un etnotopónimo.
Recursos didácticos para la enseñanza de la matemática
Authors: Cifuentes Medina José Eriberto , Chacón Benavidez José Antonio , García Gualdrón Susan Sareth , Gómez Condía Nayibe , Quiroga Garcés Julián David , Palacio Ramírez Ana Elizabeth
Published: February 2023

Las matemáticas están presentes en todos los ámbitos y quehaceres de la cotidianidad de las personas, de allí, la importancia de la enseñanzaaprendizaje de esta ciencia en el marco de la formación integral de los individuos como personas y seres sociales, ámbito en el cual, la formación de conocimiento en este campo durante la etapa de educación básica, resulta fundamental, pues, constituye la base que ha de sustentar el aprendizaje durante la educación formal y, por extensión, a lo largo de toda la vida. Esta obra es el resultado de la experiencia investigativa de los autores y directores de trabajo de grado del área mencionada, con el fin de generar una reflexión e inquietud permanente por la mejora y desarrollo, tanto de la fundamentación teórica como de la práctica educativa, de nuestra formación como investigadores y también del desarrollo profesional como docentes. En la obra se han considerado las experiencias de los estudiantes de Maestría en Didáctica de la Matemática, que se desempeñan como docentes de Educación en Básica Primaria, Básica Secundaria y Media Académica en Colombia, para ello, se ha considerado la fundamentación teórica, epistemológica y resultados de las investigaciones a lo largo de cuatro capítulos en los que se describen las problemáticas identificadas por los estudiantes en sus diferentes contextos educativos. Dentro de estas temáticas se destacan en el capítulo uno, aspectos como el desarrollo del pensamiento lógico-matemático para la resolución de problemas mediante estrategias lúdico-pedagógicas. De igual manera, en el capítulo dos, se tratan aspectos como el monopolio como estrategia didáctica para el fortalecimiento del pensamiento numérico. En este mismo sentido en el capítulo tres, se destaca la importancia de una propuesta de secuencia didáctica para fortalecer el pensamiento variacional en el estudio de funciones polinómicas. Por último, en el capítulo 4, se presenta el diseño de lámparas como recurso didáctico para el desarrollo del pensamiento geométrico en el grado séptimo.
Konsep Sustainability Tourism Dengan Tema Smart Cultural Tourism Pada Desa Penglipuran, Bali
Authors: Yasmine Belqis , Putri Betarisma , Chandra Nugroho , Zuhdi Royyan
Published: February 2023

Kebutuhan manusia akan sarana hiburan memang semakin bertambah seiring dengan adanya modernisasi dan perkembangan kebutuhan manusia. Salah satu bentuk hiburan yang sering diakses adalah pariwisata. Adanya kegiatan pariwisata juga mampu meningkatkan aspek lingkungan, ekonomi dan sosial-budaya apabila melalui perencanaan yang baik. Salah satu wisata yang memiliki potensi tinggi untuk di kembangkan adalah Desa Penglipuran. Namun, terdapat permasalahan yang dialami yaitu makin bergesernya nilai-nilai tradisional Bali pada permukiman yang berstatus sebagai atraksi atau daya tarik utama pada desa adat ini. Selain itu kurangnya pengembangan konsep perencanaan pariwisata sehingga kurang adanya diferensiasi sehingga meningkatkan persaingan dengan target pasar yang sama dengan desa wisata lain di Bali. Kurangnya kompetensi masyarakat desa dalam mengelola Desa Penglipuran sebagai destinasi wisata sehingga berdampak pada pengemasan Desa Penglipuran dalam aspek kepariwisataan. Sehingga sasaran dari penulisan ini yaitu merumuskan strategi pengembangan pariwisata dengan konsep Sustainable Tourism dengan tema Smart Culture Tourism. Analisa dilakukan dengan analisis deskriptif dan SWOT
Penataan Ruang Parkir pada Kawasan Komersial (Studi Kasus : Jalan Trunojoyo, Kabupaten Pamekasan
Authors: Ayu Riyana Aleyda , Hasanuddin Akhmad , Alfiah Rindang
Published: February 2023

Jalan Trunojoyo merupakan kawasan komersial di Kabupaten Pamekasan yang mampu menarik banyak pengunjung. Permasalahan di Jalan Trunojoyo terletak pada parkir badan jalan yang menempati dua sisi badan jalan. Hal tersebut tidak sesuai dengan kebijakan dalam Peraturan Bupati Kabupaten Pamekasan Nomor 22 Tahun 2011 yang menyebutkan bahwa parkir badan jalan berada disatu sisi jalan, yaitu sisi sebelah barat. Selain itu, permasalahan meningkat saat jam puncak, yaitu kemacetan dibeberapa titik. Sehingga diperlukan rekomendasi penataan parkir pada kawasan komersial Jalan Trunojoyo untuk meminimalisir permasalahan parkir dan mampu mendukung fungsi kawasan sebagai kawasan komersial. Penelitian ini bertujuan untuk mengetahui kondisi eksisting parkir, menghitung kebutuhan parkir, dan merumuskan rekomendasi penataan parkir di Jalan Trunojoyo. Rumusan rekomendasi penataan parkir berasal dari 3 hasil analisis, yaitu dari analisis kondisi eksisting dengan hasil terdapat ketidaksesuaian ruang parkir pada kondisi eksisting badan jalan dengan ketentuan larangan parkir yang tertuang dalam Pedoman Teknis Penyelenggaraan Fasilitas Parkir seperti pada jarak ke persimpangan, jarak ke jembatan, jarak ke jalur penyeberangan jalan, dan risiko kemacetan. Indeks parkir menunjukkan kebutuhan ruang parkir mobil lebih besar daripada kapasitas parkir yang ada, sehingga rekomendasi penataan mengarah pada penyesuaian dengan pedoman parkir dan petak parkir disesuaikan dengan penghitungan kapasitas parkir. Selanjutnya yaitu dari analisis preferensi pengunjung dalam memilih lokasi parkir menggunakan analisis faktor dalam SPSS dengan hasil 3 faktor yang menjadi prioritas pengunjung dalam memilih lokasi parkir, yaitu faktor ketersediaan, kedekatan, dan kenyamanan. Selanjutnya yaitu hasil penghitungan kebutuhan parkir yaitu 1124 m2 yang menjadi dasar dalam menentukan lokasi parkir alternatif yaitu di segmen 1 dan segmen 2.
Pengembangan Infrastruktur Perdesaan Dalam Mendukung Produktivitas Pangan Di Kecamatan Ambulu Kabupaten Jember
Authors: Sari Firda Wahyu Puspita , Suciati Luh Putu , Hayati Nunung Nuring
Published: February 2023

Pengembangan produktivitas padi dapat menjadi baik apabila didukung dengan infrastruktur perdesaan yang memadai sebagai salah satu penunjang produktivitas padi. Analisis yang di lakukan yaitu analisis skoring, analisis korelasi Spearman Rank dan Force Field Analysis (FFA). Analisis skoring di dapatkan hasil sebesar 56% yang dimakan kondisi infrastruktur dalam kondisi cukup baik. Keterkaitan infrastruktur perdesaan dengan produktivitas padi sebesar 0,651 yang termasuk kategori kuat, sehingga keterkaitan infrastruktur perdesaan  kuat dengan produktivitas pangan di Kecamatan Ambulu dan untuk stategi yang di dapatkan berdasarkan pendorong dan penghambat yang telah di pilih dengan cara menyinerginakan antara beberapa pihak yang terkait dan dapat membantu perwujudan keberadaan pengembangan infrastruktur perdesaan dalam mendukung produktivitas pertanian Kecamatan Ambulu agar di manfaatkan secara kontinyu. Tidak hanya sampai disitu, diperlukan juga pendampingan kelompok – kelompok tani yang bisa membantu para petani dalam mendukung tercapainya panen padi sehingga bisa dilakukan evaluasi secara berkala. Melakukan Forum Group Discussion (FDG) yang mana setiap masukan dan kendala dari para petani bisa didiskusikan secara bersama untuk mencarikan solusi yang tepat.
PEMODELAN MATEMATIKA PENYEBARAN COVID-19 DENGAN MODEL SVEIR
Authors: Septiansyah Gian , Karim Muhammad Ahsar , Yulida Yuni
Published: February 2023

Coronavirus disease 2019 or also known as Covid-19 is a disease caused by a type of coronavirus called Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) or better known as the corona virus. Covid-19 become a pandemic since 2020 and has been widely studied, one of which is in mathematical modeling. In this study, the spread of Covid-19 is modeled using the SVEIR (Susceptible, Vaccination, Exposed, Infected, and Recovered) model. The purpose of this study explains the formation of the Covid-19 SVEIR model, determines the equilibrium point, determines the basic reproduction number, and analyzes the stability of the Covid-19 SVEIR model. The purpose of this study explains the formation of the Covid-19 SVEIR model, determines the equilibrium point, the basic reproduction number, and analyzes the stability of the Covid-19 SVEIR model. The result of this study is to explain the formation of the Covid-19 SVEIR model and obtained two equilibrium points, the disease-free equilibrium point and the endemic equilibrium point. Furthermore, the basic reproduction number  is obtained through the Next Generation Matrix method. The results of the stability analysis at the disease-free equilibrium point were locally asymptotically stable with conditions  while at the endemic equilibrium point local asymptotically stable with conditions . The natural death rate is greater than the effective contact rate. A numerical simulation is presented to show a comparison spread of Covid-19 by providing different levels of vaccine effectiveness using the Runge-Kutta Order method.
SIFAT-SIFAT KOSET FUZZY DARI SUBGRUP FUZZY SUATU GRUP
Authors: Yanwar Muhammad Rifaldy , Abdurrahman Saman , Hijriati Na'imah
Published: February 2023

Konsep himpunan fuzzy digunakan untuk mempresentasikan suatu permasalahan yang sulit dinyatakan melalui himpunan tegas. Kemudian, penelitiaan konsep himpunan fuzzy dikombinasikan dengan bidang aljabar yang melahirkan konsep aljabar fuzzy. Penelitian aljabar fuzzy salah satunya adalah grup fuzzy. Dari penelitian ini memberikan ide bagi peneliti lainnya, yaitu seperti meneliti koset fuzzy dan terbentuknya grup faktor dari subgrup normal fuzzy. Koset fuzzy pada penelitian terbaru berupa koset kiri fuzzy, koset kanan fuzzy, dan koset tengah fuzzy. Tujuan penelitian ini adalah membuktikan sifat-sifat koset kiri fuzzy, koset kanan fuzzy dan koset tengah fuzzy, serta mengkaji hubungan pada koset kiri fuzzy dan koset kanan fuzzy dengan koset tengah fuzzy dari subgrup fuzzy suatu grup. Prosedur penelitian ini diawali dengan mempelajari konsep dasar yang digunakan dalam penelitian ini. Kemudian, dengan menggunakan konsep dasar tersebut, dibuktikan sifat-sifat koset kiri fuzzy, koset kanan fuzzy dan koset tengah fuzzy. Selanjutnya, mengkaji hubungan pada koset kiri fuzzy dan koset kanan fuzzy dengan koset tengah fuzzy pada subgrup fuzzy suatu grup. Hasil penelitian ini adalah pada subgrup fuzzy atas grup abelian, koset kiri fuzzy merupakan koset kanan fuzzy. Setiap subgrup fuzzy atas sebarang grup,  dengan  elemen identitas. Pada penelitian ini diperoleh juga syarat cukup dan syarat perlu kesamaan dua koset kiri (koset kanan) yang terbentuk dari dua subgrup fuzzy atas grup yang sama ataupun atas grup abelian yang sama, serta syarat cukup dan syarat perlu kesamaan dua koset tengah yang terbentuk dari dua subgrup fuzzy atas grup yang sama
KELAYAKAN PENGEMBANGAN KONTEN INSTAGRAM BERBASIS AUTHENTIC PROBLEM UNTUK MENINGKATKAN LITERASI SAINS PESERTA DIDIK SMP
Authors: Puspitasari Usie , Syahmani Syahmani , Suryajaya Suryajaya
Published: February 2023

This research was conducted with the aim of producing Instagram content as an Authentic Problem-based science learning media to improve scientific literacy of junior high school students. This research is a development research, where the research and development steps are carried out using the ADDIE model. The feasibility of the development carried out is seen from its practicality and effectiveness. Where the average value of RPP implementation for 5 meetings is 3.84 in the very good category with a reliability of 0.69 in the high category. Then the scientific literacy obtained an N-gain score of 0.60 in the medium category. Then after carrying out the normality test and homogeneity test, the t test for scientific literacy was continued with the results of sig. pretest of 0,596 and sig. posttest of 0.949. So Ho is rejected and Ha is accepted. So the conclusion is that there is a significant difference in the value of the treatment with media content and without media content.Keywords: instagram, authentic problem, scientific literacy. ABSTRAKPenelitian ini dilakukan dengan tujuan menghasilkan konten instagram sebagai media pembelajaran IPA berbasis Authentic Problem untuk meningkatkan literasi sains peserta didik SMP. Penelitian ini merupakan penelitian pengembangan, dimana langkah-langkah penelitian dan pengembangan yang dilakukan menggunakan model ADDIE kelayakan pengembangan yang dilakukan dilihat dari kepraktisan dan keefektivan. Dimana nilai rerata keterlaksanaan RPP selama 5 pertemuan sebesar 3,84 berkategori sangat baik dengan reliabilitas sebesar 0,69 berkategori tinggi. Kemudian pada literasi sains diperoleh skor N-gain sebesar 0,60 dengan kategori sedang.Lalu setelah melakukan uji normalitas dan uji homogenitas maka dilanjutkan uji t untuk literasi sains dengan hasil sig. pretest sebesar 0,596 dan sig. posttest sebesar 0,949. Maka Ho ditolak dan Ha diterima. Jadi kesimpulannya terdapat perbedaan nilai yang signifikan terhadap perlakuan dengan konten media dan tanpa konten media.Kata kunci: instagram, authentic problem, literasi sains.
PERANGKAT PEMBELAJARAN KOOPERATIF BERBASIS STEM: USAHA UNTUK MENINGKATKAN LITERASI SAINS PESERTA DIDIK
Authors: Hasanah Nurannisa Fatona Sartimulya , Suyidno Suyidno , Mahtari Saiyidah
Published: February 2023

Scientific literacy is one of the skills needed in the 21st century but there are no learning device that support increasing scientific literacy, causing student’s scientific literacy skills to be low.  The purpose of this research is to produce STEM based cooperative learning device on mechanical wave materials that are appropriate to improve student’s scientific literacy. The learning device developed includes lesson plans, teaching materials, activities worksheet and scientific literacy test.  This research is a development research with the ADDIE model and uses a one group pre-test and post-test trial design on 27 students of class XI IPA 3 SMAN 3 Banjarmasin.  The results of the research show that STEM based cooperative learning device are valid, because of lesson plans, teaching materials, activities worksheet and scientific literacy test in valid criteria and effective, because the N-Gain value of scientific literacy is 0.53 which indicates an increase in the moderate criteria. Thus the STEM based cooperative learning device developed is feasible to improve student’s scientific literacy.Keywords: cooperative learning, mechanical wave, scientific literacy, STEM. ABSTRAKLiterasi sains merupakan salah satu keterampilan yang dibutuhkan di abad 21, namun belum terdapat perangkat pembelajaran yang mendukung peningkatan literasi sains menyebabkan kemampuan literasi sains peserta didik menjadi rendah. Tujuan penelitian ini adalah menghasilkan perangkat pembelajaran kooperatif berbasis STEM pada materi gelombang mekanik yang layak untuk meningkatkan literasi sains peserta didik. Perangkat pembelajaran yang dikembangkan meliputi RPP, materi ajar, LKPD dan LP literasi sains. Penelitian ini merupakan penelitian pengembangan dengan model ADDIE dan menggunakan desain uji coba one group pre-test and post-test pada 27 peserta didik kelas XI IPA 3 SMAN 3 Banjarmasin. Hasil penelitian menunjukkan bahwa perangkat pembelajaran kooperatif berbasis STEM termasuk valid, karena RPP, materi ajar, LKPD dan LP literasi sains dalam kriteria valid serta termasuk efektif, karena nilai N-Gain literasi sains sebesar 0,53 yang menunjukan peningkatan dalam kriteria sedang. Dengan demikian perangkat pembelajaran kooperatif berbasis STEM yang dikembangkan layak untuk meningkatkan literasi sains peserta didik.Kata kunci: gelombang mekanik, literasi sains, pembelajaran kooperatif, STEM.
PENGARUH LKPD BERBASIS CULTURE LITERACY DIGITAL WETLAND (CLDW) PADA KONSEP PERUBAHAN LINGKUNGAN TERHADAP HASIL BELAJAR SISWA KELAS X SMA
Authors: Br Solin Julita Hotmaida , Putra Aminuddin Prahatama , Hardiansyah Hardiansyah
Published: February 2023

Culture Literacy Digital Wetland (CLDW) is a software designed to create, distribute, and manage the delivery of learning content similar to the Learning Management System. This study aims to determine student learning outcomes by using CLDW LKPD-based worksheets on the concept of environmental change. This type of research uses a quasi-experimental method (pseudo-experiment). The sample of this research was class X students of SMAN 7 Banjarmasin which were divided into one treatment class and one control class. The results of learning data were analyzed using the Independent Sample T-test using the SPSS 25 program. From the results obtained, namely learning outcomes showed that the use of CLDW-based LKPD had a significant effect on learning outcomes with a value of the Sig level. (2 tailed) = 0.000 0.05 and the t-count value is 4.150 t-table 1.99444. It is hoped that the results of this study can provide innovation to teachers in the use of learning media in the form of CLDW-based worksheets, especially in online learning so that they can motivate students and for further research to pay attention to the factors that hinder the learning process.Keywords: CLDW, learning outcomes, LKPD, environmental changes. ABSTRAKCulture Literacy Digital Wetland (CLDW) merupakan salah satu perangkat lunak yang dirancang untuk membuat, mendistribusikan, serta mengatur penyampian isi konten pembelajaran yang sama halnya dengan Learning Management System. Penelitian ini bertujuan untuk mengetahui hasil belajar siswa dengan penggunaan LKPD berbasis CLDW LKPD pada konsep perubahan lingkungan. Jenis penelitian ini menggunakan metode quasi exsperimen (eksperimen semu). Sampel penelitian ini adalah siswa kelas X SMAN 7 Banjarmasin yang dibagi menjadi satu kelas perlakuan dan satu kelas kontrol. Hasil data belajar dianalisis dengan menggunakan uji Independent Sample T–test dengan menggunakan program SPSS 25. Dari hasil penelitian yang diperoleh yaitu hasil belajar menunjukkan bahwa penggunaan LKPD berbasis CLDW berpengaruh signifikan terhadap hasil belajar dengan nilai dari taraf Sig. (2 tailed) = 0,000 0,05 dan nilai t hitung 4.150 t tabel 1,99444. Diharapkan hasil penelitian ini dapat memberikan inovasi terhadap guru dalam penggunaan media pembelajaran berupa LKPD berbasis CLDW terutama dalam pembelajaran daring sehingga dapat memotivasi siswa dan untuk penelitian selanjutnya agar memperhatikan faktor-faktor yang menghambat dalam proses pembelajaran.Kata kunci: CLDW, hasil belajar, LKPD, perubahan lingkungan.
Blockchain Database and IoT: A Technology driven Agri-Food Supply Chain
Authors: Hasan Ikram , Habib Md. Mamun , Mohamed Zulkifflee
Published: February 2023

This article explores the potential of blockchain database and Internet of Things (IoT) technologies to improve the trustworthiness of the agri-food supply chain. It provides an overview of the challenges facing the supply chain, including food safety, traceability, and sustainability, and how blockchain and IoT can address these challenges based on secondary data. This paper presents a case study of a blockchain-based platform that utilizes IoT sensors to provide end- to-end visibility and traceability of food products. The findings demonstrate the potential for this technology to improve food safety, reduce waste, and increase transparency in the agri-food supply chain. Overall, the study demonstrates the potentiality of blockchain and IoT in revolutionizing the agri-food industry and creating a more trustworthy, responsible and sustainable food system.
HOTELSKA KAVA I NOVI TRENDOVI U UGOSTITELJSTVU
Authors: Trusić Domagoj
Published: February 2023

Hotelski sustav ima više modula ugostiteljstva te je u svakom prisutna kava kao proizvod i usluga. Pristup za svaki modul je drugačiji te postoje parametri koji definiraju koja kava se služi u kojem ugostiteljskom modulu. Uvođenje novih trendova u kavi donosi osvježenje u ponudu hotelskog sustava, ima imperativ podizanja kvalitete sirovine na specialty kvalitetu te kuhanja i posluživanja kave prema potrebama modula. Trendovi u ugostiteljstvu promijenili su navike gosta i u kavi. Kava kao finalni proizvod mora poštivati proizvodne standarde, što uniformiranost proizvoda i svježinu postavlja kao imperativ. Očekivanja gosta od šalice kave su se povećala jer je senzibilizirao nepce. Cijeni se porijeklo i transparentnost, kako u hrani, tako i u kavi, tako da proizvod s više informacija ima veću vrijednost. Kvaliteta napitka ponekad ne ovisi o kvaliteti kave, već i o stilu kuhanja. Funkcionalnost i cijena nisu više jedini parametri pri odabiru. Kava u hotelu treba biti bez brenda, ali jasno definirane i komunicirane kvalitete. Specialty kvaliteta kave i educirani barista su obligatorni za 4+ kategorizaciju hotela jer to prati ostalu ponudu.
Power Management in Micro grid Using Hybrid Energy Storage System
Authors:   PG scholar, Department of EEE,Dhanalakshmi Srinivasan,College of Technology,Chennai, Tamil Nadu, Ms S.Maga , Ms C.Kavitha ,   Assistant Professor,Department of EEE,Dhanalakshmi Srinivasan College of Technology,Chennai, Tamil Nadu
Published: February 2023

This paper proposed for power management in micro grid using a hybrid distributed generator based on photovoltaic, wind-driven PMDC and energy storage system is proposed. In this generator, the sources are together connected to the grid with the help of interleaved boost converter followed by an inverter. Thus, compared to earlier schemes, the proposed scheme has fewer power converters. FUZZY based MPPT controllers are also proposed for the new hybrid scheme to separately trigger the interleaved DC-DC converter and the inverter for tracking the maximum power from both the sources. The integrated operations of both the proposed controllers for different conditions are demonstrated through simulation with the help of MATLAB software.
Review of Basic Principles of Embodiment Design
Authors:   Post graduate student, Ms Tesfaye Olana
Published: February 2023

Abstract: A number of technical research fields have grown and matured over decades through the investigation, study, experimentation, and validation of core principles. Accepted research methodologies and standards similarly emerge and mature, but also tailored to the characteristics and scope of the field. The life and physical sciences are classical examples of this growth and maturation process. Principles of embodiment design is a relatively young field of research investigation. With the first treatises published around the mid-twentieth century, it has grown steadily in the devoted attention and depth of investigation. Because of the broad and interdisciplinary or trans-disciplinary nature of design principles, numerous forms have been suggested across disciplines, between disciplines, and at various levels of granularity or specificity. The time is now apparent to carefully study these efforts, seeking a formaliz��ation of embodiment design principles, definitions, and supporting research methodologies. In this review, I seek to make strides in formalizing principles of embodiment design in terms of the various disparate approaches. Ultimately, this review assists in enabling a fundamental understanding and development of embodiment design principles, and associated processes, as well as guiding researchers and practitioners in advancements and use of such principles
Dynamic Ramsey Theory of Mechanical Systems Forming a Complete Graph and Vibrations of Cyclic Compounds
Authors: Shvalb Nir , Frenkel Mark , Shoval Shraga , Bormashenko Edward
Published: February 2023

Ramsey theory influences the dynamics of mechanical systems, which may be described as abstract complete graphs. We address a mechanical system which is completely interconnected with the two kinds of ideal Hookean springs. The suggested system mechanically corresponds to the cyclic molecules, in which functional groups are interconnected with two kinds of chemical bonds, represented mechanically with two springs k1 and k2. In this paper, we consider a Cyclic system (molecule) built of six equal masses m and two kinds of springs. We pose the following question: what is the minimal number of masses in the such a system in which three masses are constrained to be connected with spring k1 or three masses to be connected with spring k2? The answer to this question is supplied by the Ramsey theory, and it is formally stated as follows: what is the minimal number R3,3? The result emerging from the Ramsey theory is R3,3=6. Thus, in the aforementioned interconnected mechanical system will be necessarily present the triangles (at least one triangle), built of masses and springs. This prediction constitutes the vibrational spectrum of the system. Thus, the Ramsey Theory supplies the selection rules for the vibrational spectra of the cyclic molecules. Symmetrical system built of six vibrating entities is addressed. The Ramsey approach works for 2D and 3D molecules, which may be described as abstract complete graphs. The extension of the proposed Ramsey approach to the systems, partially connected by ideal springs, viscoelastic systems and systems, in which elasticity is of an entropy nature is discussed. “Multi-color systems” built of three kinds of ideal springs are addressed. The notion of the inverse Ramsey network is introduced and analyzed.
Drawbacks of Immune Checkpoint Inhibition and Rigorous Management for Immune Related Adverse Events Along with a Strategy Against Tumor Plasticity
Authors: Hendekli C. Mehmet
Published: February 2023

Immune checkpoint inhibition therapy (ICIT) is an emerging field in oncology especially opening new horizons to chemotherapy refractory patients. This paper provides deep insight into immune related adverse events (irAEs) posing a major challenge and drawback to ICIT, and presents right management strategies for very complex complications. Moreover, a non-linear mathematical approach to measure the ICIT success rate and a strategy to overcome or to delay the progression after initial good response to ICIT in a subset of patients are presented, respectively.
Path Planning in Case of Swarm Unmanned Surface Vehicles for Visiting Multiple Targets
Authors: Ntakolia Charis , V. Lyridis Dimitrios
Published: February 2023

In this study we present a hybrid approach of ACO with fuzzy logic and clustering methods to solve multi-objective path planning problems in case of swarm USVs. This study aims to enhance the performance of ACO algorithm by integrating fuzzy logic in order to cope with the multiple contradicting objectives and generate quality solutions by in parallel identifying the mission areas of each USV to reach the desired targets. The objectives that are taken into account are the minimization of traveled distance and energy consumption, and the maximization of path smoothness. A comparative evaluation is conducted among ACO and fuzzy inference systems, Mamdani (ACO-M) and Takagi–Sugeno–Kang (ACO-TSK). The results showed that depending on the needs of the application, each methodology can contribute respectively. ACO-M generates better paths but ACO-TSK presents higher computation efficiency.
Self-Reported Adverse Events after Primary COVID-19 Vaccination in Bulgarian Healthcare Workers
Authors: Rangelova Vanya , Raycheva Ralitsa Dimitrova , Kevorkyan Ani , Sariyan Sara , Tzekov Valeri
Published: February 2023

The immunization of healthcare workers in the early stages of the rollout of COVID-19 vaccines was prioritized in order to ensure uninterrupted medical care provision. At the same time the increasing number of available COVID-19 vaccines may trigger hesitancy towards the decision to get vaccinated. Thus, accumulating reliable information on the adverse events following immunization may educate and urge the general population to receive a COVID-19 vaccine. The present study aimed to evaluate the adverse events (AEs) following immunization with any of the available COVID-19 vaccine among Bulgarian healthcare workers (HCWs). A cross-sectional study among HCWs in Plovdiv, Bulgaria was conducted in the period March – September 2021. Through a semi-structured online questionnaire, the participants reported the adverse events following the administration of the first and second dose of a COVID-19 vaccine. A total of 253 respondents, vaccinated with one of the available vaccines against COVID-19 took part in the study. Of them 71.9% were females, and 75.9% received mRNA-based vaccines, while 24.1% received a viral-vector based vaccine. Overall 91.6% and 82.6% of all participants reported at least one local AE after the first and second dose of a COVID-19 vaccine. The share of respondents reporting at least one systemic AE after the first and second dose of a COVID-19 vaccine was 59.7% and 62.4% respectively. The most common local AE was pain at the injection spot (84.0%), while the most common systemic AEs were fatigue (54.9%), chills (43.2%), and headache (41.7%). The mRNA-based vaccines versions seem to cause higher prevalence of local AEs, while the vector-based vaccines were linked with increased prevalence of systemic AEs. Female HCWs and the younger age group were associated with an increased risk of adverse events generally. Our results added more evidence that mRNA-based and viral-vector based vaccines are generally safe. The reported adverse events were mild, although they occurred in a high share of the respondents. No serious AEs attributable to the vaccines were reported.
The Bioactivity of Green-Synthesized Noble Metal Nanoparticles Against Streptomycin-Resistant Bacillus Sp. Is Enhanced by Bioconjugation with Streptomycin
Authors: Ramasami N. , Dhayalan M. , Selvaraj M. , Mohammed Riyaz S. U. , Palani Perumal , Kanthapazham Raja kumar , Zherebtsov D. , Mejuto J. C. , Simal-Gandara J. , Cid-Samamed A.
Published: February 2023

Background: Combinatorial therapy- “nano antibiotics” is an emerging field in nanoscience. In this present investigation, we attempted to combine the green synthesized noble metal nanoparticle and the antibiotic Streptomycin to form bio-conjugated nanoparticles. The newly synthesized Nano antibiotics acted as the antibiotic carrier, functioned as cargo, and delivered the antibiotic. Methods: Comparative studies between the noble metal nanoparticles were attempted for the first time on the grounds of their antibacterial activity. The antibacterial activity of the three noble metal nanoparticles was assessed against Streptomycin-resistant Bacillus sp.; the results obtained proved that silver nanoparticles were a potent antibacterial agent. Still, no antibacterial activity was exerted by gold, and platinum nanoparticles were for the Streptomycin-resistant strain Bacillus sp. To our surprise, the gold and platinum fabricated/bio-conjugated nanoparticle with the antibiotic showed 100% antibacterial activity, whose antibacterial activity was zero when functioning as a nanoparticle alone. Results: The combinatorial therapy of two different clauses of drugs majorly increased antibacterial activity. It enhanced the antibiotic to overcome the resistance exhibited by the bacterial pathogen, and the possible mechanism is elucidated in the present study. Also, an attempt has been made to assess the nanotoxicity of the nano-bioconjugates on RBC and compare their hemocompatibility. The results obtained in the current investigation demonstrate the enhanced antibacterial activity of the green synthesized nanoparticles conjugated with the streptomycin; their efficacy for combinational therapy against resistance in pathogenic organisms highlights the novelty of the work and the comparative study of three different noble metals nanoparticles (Ag, Au, Pt) from single agro-waste for the first time.
Steganalysis of Chat based Steganography
Authors: Okello Moses Oyaro
Published: February 2023

Steganalysis is the practice of identifying potential secret communication and taking appropriate action, such as deciphering to uncover the hidden contents or destroying the object containing the hidden information if it cannot be uncovered. At times, it’s very necessary to perform Steganalysis due to the fact that steganography is often misused by those with bad intentions, making it a platform for criminal communication. This paper presents a methodology for the detection of timing steganography. The method is based on user behavior during chat, such as the time taken to read, edit, and send text, etc. The method was tested using simulation-based chat software, and it can detect intended timing samples correctly. However, this method is not a very robust one due to some reasons. For instance, it only works well with text-based chat applications, and there are many factors that affect the typing and reading speed of an individual as well as their behavior during chat. These often make the method susceptible to fault detection as it is not easy to set an accurate mean value and deviation to accommodate different typists' normal behavior, which appears as an intended timing.