bluuebunny/crossref_metadata_2025 huggingface dataset:
Neuropsychological Assessment in the Distinction Between Biomarker Defined Frontal-Variant of Alzheimer’s Disease and Behavioral-Variant of Frontotemporal Dementia
Authors: Lima Marisa , Tábuas-Pereira Miguel , Durães João , Vieira Daniela , Faustino Pedro , Baldeiras Inês , Santana Isabel
Published: January 2023

Background: Frontal-variant of Alzheimer’s disease (fvAD) was purposed for patients with AD pathology that, despite the typical amnestic presentation, show early and progressive deterioration of behavior and executive functions, closely resembling the behavioral-variant of frontotemporal dementia (bvFTD). This leads to a challenging differential diagnosis where neuropsychological evaluation and in vivo pathological evidence are essential. Objective: To evaluate the contribution of a comprehensive neuropsychological assessment (NP) battery in distinguishing between fvAD-dementia and bvFTD supported by cerebrospinal fluid (CSF) biomarkers. Methods: We included 40 patients with a baseline NP profile with prominent early executive and/or behavioral dysfunction, who meet both diagnosis of bvFTD and fvAD-dementia, according to international criteria. All patients underwent comprehensive NP assessment and CSF-AD biomarker evaluation. Neuropsychological domains as well as clinical and sociodemographic features, and APOE genotype were compared between groups. Results: 21 patients (52.5%) met the biological criteria for AD (decreased Aβ42 together with increased T-tau or P-tau in CSF) and were therefore classified as fvAD (mean age was 64.57, with 47.6% female). There were no differences between groups regarding age/age-at-onset, gender, or educational level. Regarding neuropsychological profile, performances in language and memory functions were equivalent in both groups. Significant differences were found in visuo-constructional abilities (p = 0.004), Trail Making Test A (p < 0.001), and Raven’s Colored Progressive Matrices (p = 0.019), with fvAD patients showing worst performances. Conclusion: In patients with an early prominent frontal profile, a higher impairment in attention and visuo-spatial functions, signaling additional right hemisphere fronto-parietal dysfunction, point towards a diagnosis of fvAD-dementia and may be useful in clinical practice.
A Child with Refractory and Relapsing Anti-3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase Myopathy: Case-Based Review
Authors: Sener Seher , Batu Ezgi Deniz , Sari Seher , Kasap Cuceoglu Muserref , Yildiz Adalet Elcin , Talim Beril , Aydingoz Ustun , Ozen Seza , Haliloglu Goknur
Published: January 2023

Background/Objective: Anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase (anti-HMGCR) myopathy is rare in children. Here, we present a boy with relapsing refractory anti-HMGCR myopathy along with a systematic literature review. Case Report: 17-year-old boy with five years of muscle weakness, rash, high creatinine kinase (CK) levels, and muscle biopsy compatible with inflammatory myopathy was diagnosed with juvenile dermatomyositis. He was treated with corticosteroids, intravenous immunoglobulin (IVIG), and methotrexate. His muscle weakness improved with this treatment although never completely resolved. CK levels decreased from ∼15000 U/L to ∼3000 U/L. At the age of 15, muscle weakness relapsed after an upper respiratory tract infection; pulse corticosteroid treatment was administered. The re-evaluated muscle biopsy showed a necrotizing pattern and the HMGCR antibody was positive confirming anti-HMGCR myopathy when he was 16. The diagnostic delay was 50 months. Disease activity was monitored by Medical Research Council score, MRI and functional tests. Despite corticosteroids, methotrexate, IVIG, cyclosporine A, and rituximab therapies, muscle weakness improved only slightly during the first three months and remained stable afterwards. Results of the Literature Search: We identified 16 articles describing 50 children (76% female) with anti-HMGCR myopathy by reviewing the English literature up to March 1st, 2022. Proximal muscle weakness was the most common clinical symptom (70.8%). Corticosteroids (84.8%), IVIG (58.7%), and methotrexate (56.5%) were preferred in most cases. Complete remission was achieved in nine patients (28.1%). Conclusion: Diagnosis and management of children with anti-HMGCR myopathy are challenging. Complete remission is achieved in only one third of these patients. Imaging biomarkers may aid treatment.
Approaches for combining data from multiple probability samples
Authors: Dzikiti Loveness N. , Vieira Marcel D.T. , Girdler-Brown Brendan
Published: January 2023

Even though there is substantial literature on studies that pool survey data, it is still not clear which are the most efficient methodologies and sampling designs for combining data from different surveys. For example, it is important to know whether the estimates from the different surveys involved should be given equal weights in the calculation of the combined statistics or not. If they are not given equal importance, then it should be clear how they should be weighted and why. In this paper, current and proposed methods considered to combine survey data are evaluated through simulation, in the context of simple random sampling, stratified random sampling and two stage cluster random sampling from finite populations generated from a normal distribution super-population model. Simulation results suggest superpopulation variance does not influence the choice of weighting method. However, the population size appears to influence this choice. Combining samples improved the precision of estimates regardless of weighting method used for data collected under all considered sampling techniques, with stratified sampling being more precise than simple random sampling and two stage random cluster sampling.
Overview of the use of big data for official statistics in Latin America and the Caribbean
Authors: Diniz da Silva Andrea , Menezes Marques de Oliveira Beatriz , Gonçalves Peixoto Ísis , Braga Sales de Souza Lidiane
Published: January 2023

In 2020 and 2021, the challenges related to the decline in the financing of statistical production and the cooperation of respondents was exacerbated by the COVID-19 pandemic. This scenario led national statistical offices (NSOs) to accelerate consideration of alternative data sources to complement or even replace traditional survey data. In this context, the use of big data to produce statistics has become promising. The use of big data for statistics is already in practice in many parts of the Global North and has also been spreading rapidly in the South. Part of the success of this trend is due to the support of the United Nations Committee of Experts on Big Data and Data Science for Official Statistics (UNCEBD), in particular its four Regional Hubs for Big Data. To learn the extent of the use of big data for official statistics in Latin America and the Caribbean, the United Nations Regional Hub for Big Data in Brazil conducted a study of the practices of NSOs in the region. A very promising scenario was found regarding the use of big data from satellite imagery, web scraping and other big data sources, for applications such as the production of price statistics, land use and cover patterns and migration.
Diagnostic value of multi-parameter MRI and colour B-ultrasound elastography in benign and malignant thyroid nodules
Authors: Wang Fan , Zhang Liping , Jiao Junxia
Published: January 2023

BACKGROUND: The early diagnosis of thyroid cancer depends on the popularisation and development of diagnostic imaging techniques and the continuous improvement of physician diagnosis. OBJECTIVE: To investigate the clinical value of multi-parameter magnetic resonance imaging (MRI) and colour B-ultrasound elastography in thyroid nodules. METHODS: The clinical and imaging data of 252 patients with thyroid nodules who were admitted to our hospital were collected. All patients underwent preoperative colour B-ultrasound elastography and MRI. The postoperative pathological results were the gold standard for diagnosing benign and malignant thyroid nodules. The accuracy, sensitivity and specificity of MRI, colour B-ultrasound elastography and their combination for diagnosing benign and malignant thyroid nodules were compared. RESULTS: This study included 252 patients with 388 nodules. There were 169 patients with solitary nodules and 83 patients with multiple nodules. The maximum diameter of the thyroid nodules was 0.32–1.00 (0.75 ± 0.20) cm. The accuracy of MRI diagnosis (348/388) was 89.69%, the sensitivity was 92.98%, and the specificity was 65.22%. The diagnostic accuracy, sensitivity and specificity of colour B-ultrasound elastography (332/388) were 85.57%, 88.30% and 65.22%, respectively. The accuracy rate of combined diagnosis (376/388) was 96.91%, the sensitivity was 98.25%, and the specificity was 86.96%, which was significantly higher than MRI and colour B-ultrasound elastography alone. The area under the curve (AUC) of MRI, colour B-ultrasound elastography and combined diagnosis were 0.768, 0.791 and 0.926, respectively. The AUC of the three diagnostic methods was > 0.7, indicating that the three diagnostic methods had good diagnostic value. The AUC for combined diagnosis was significantly higher than that of MRI and colour B-mode ultrasound elastography alone. CONCLUSION: Combined ultrasound and MRI have high diagnostic accuracy and specificity for benign and malignant thyroid nodules. This diagnostic method can be applied in clinical practice.
Cost supervision mining from EMR based on artificial intelligence technology
Authors: Xu Site , Zhang Tiantian , Sheng Tao , Liu Jiaxing , Sun Mu , Luo Li
Published: January 2023

BACKGROUND: To effectively monitor medical insurance funds in the era of big data, the study tries to construct an inpatient cost rationality judgement model by designing a virtuous cycle of inpatient cost supervision information system and exploring a complete set of inpatient cost supervision methods. OBJECTIVE: To lay the foundation for applying artificial intelligence (AI) technology in medical insurance cost control supervision and provide feasible paths and available tools for medical insurance cost control managers. METHODS: By way of collecting and cleaning electronic medical record (EMR) data from 2016 to 2018 of a city in East China, focusing on basic patient information and cost information, and using a combination of machine learning modeling and information system construction, the study tries to form a feasible inpatient cost supervision method and operation path. RESULTS: The set of the regulatory method, applied in nursing homes of a city in East China, is compelling. The accuracy rates of rationality judgement in different main diseases are stable up to 80%, the false positive rate is steady within 10%, and rehabilitation fee days of hospitalization, and the number of complications are important factors affecting the rationality of the inpatient cost. CONCLUSION: The model construction and optimization method combining machine learning and information system can make practical cost rationality judgement on medical institution’s inpatient cost data, which can directly reflect the key influencing factors of relevant inpatient costs, and achieve the effect of guiding medical behavior and improving the efficiency of medical insurance fund use.
Advanced method of rehabilitating edentulous Jaws: A review on telescopic denture
Authors: Minervini Giuseppe , Cervino Gabriele , Chaturvedi Saurabh , Franco Rocco , di Francesco Fabrizio , Fiorillo Luca , Cicciù Marco
Published: January 2023

BACKGROUND: Edentulism conducts to a recognized impairment of oral function with both aesthetic and psychological changes. These patients suffer from a multiplicity of problems with their dentures, such as insufficient stability, retention and pain during mastication. The rehabilitation of a part edentulous patient can be established using a wide range of prosthetic treatment options. The overdenture treatment uses a removable total denture that overlies retained teeth, tooth roots, or dental implants. In the literature it was shown that patients with removable overdentures supported and retained either by tooth roots or implants have more predictable prosthodontic outcomes. OBJECTIVE: The aim of this review is to provide an overview on the overdenture with a focus on the tooth-supported telescopic overdenture. METHODS: The literature research was performed in the Scopus, Web of Science, and Pubmed electronic databases. Document type was limited to papers written in English, without time restrictions. The Review was recorded in the international PROSPERO (International Prospective Register of Systematic Reviews) database with the following number CRD42022326415. RESULTS: A total of 256 articles published were found from electronic searches, Two independent reviewers carried out the screening and the selection process for the studies. First, duplicate citations were eliminated. Then, the two Authors independently screened the retrieved articles by title and abstract of each citation to determine its suitability for inclusion. Finally, 13 full-text articles satisfied the inclusion criteria. CONCLUSION: Prostheses supported by Frictional telescopic crowns offer an effective treatment alternative for patients with Severely reduced dentitions who do not want implant treatment or complete dentures.
BiRPN-YOLOvX: A weighted bidirectional recursive feature pyramid algorithm for lung nodule detection
Authors: Han Liying , Li Fugai , Yu Hengyong , Xia Kewen , Xin Qiyuan , Zou Xiaoyu
Published: January 2023

BACKGROUND:

Lung cancer has the second highest cancer mortality rate in the world today. Although lung cancer screening using CT images is a common way for early lung cancer detection, accurately detecting lung nodules remains a challenged issue in clinical practice.

OBJECTIVE:

This study aims to develop a new weighted bidirectional recursive pyramid algorithm to address the problems of small size of lung nodules, large proportion of background region, and complex lung structures in lung nodule detection of CT images.

METHODS:

First, the weighted bidirectional recursive feature pyramid network (BiPRN) is proposed, which can increase the ability of network model to extract feature information and achieve multi-scale fusion information. Second, a CBAM_CSPDarknet53 structure is developed to incorporate an attention mechanism as a feature extraction module, which can aggregate both spatial information and channel information of the feature map. Third, the weighted BiRPN and CBAM_CSPDarknet53 are applied to the YOLOvX model for lung nodule detection experiments, named BiRPN-YOLOvX, where YOLOvX represents different versions of YOLO. To verify the effectiveness of our weighted BiRPN and CBAM_ CSPDarknet53 algorithm, they are fused with different models of YOLOv3, YOLOv4 and YOLOv5, and extensive experiments are carried out using the publicly available lung nodule datasets LUNA16 and LIDC-IDRI. The training set of LUNA16 contains 949 images, and the validation and testing sets each contain 118 images. There are 1987, 248 and 248 images in LIDC-IDRI’s training, validation and testing sets, respectively.

RESULTS:

The sensitivity of lung nodule detection using BiRPN-YOLOv5 reaches 98.7% on LUNA16 and 96.2% on LIDC-IDRI, respectively.

CONCLUSION:

This study demonstrates that the proposed new method has potential to help improve the sensitivity of lung nodule detection in future clinical practice.
An Analysis on EFL Learners’ Perspectives of Online Learning during Covid-19 Pandemic
Authors: Maysuroh Siti , Wati Laila , Dwimaulani Astrid , Yusri Nurul , Sholihah Siti Zurriyatun
Published: January 2023

The aim of this research is to investigate EFL students’ perspectives on the utilization of online learning during the COVID-19 pandemic. A survey method was applied. This research involves 40 students of the second, fourth, and sixth semesters of the English Study Program of a private University in Hamzanwadi for the academic year 2020-2021 as the participants. To collect the data, a questionnaire was administered via Google Forms. The data collected were then analyzed using a percentage formula. The results of the study indicate that most of the students believe that online learning has not provided a better experience dan results in improving their competencies. However, they agreed that it provides ease in their learning. In addition, based on the result of questionnaires, more than 50% of the students prefer direct-classroom learning to online learning and only resettled with online learning during the COVID-19 pandemic. In a nutshell, despite the COVID-19 pandemic, students still choose direct classroom learning.
Factors Influencing Speaking Anxiety of FLSP Freshmen
Authors: Alfiani Widya , Asib Abdul , Supriyadi Slamet
Published: January 2023

Anxiety is one of the biggest challenges that has harmed language development. Among the four-language skill, speaking is the most anxiety-provoking skill. This present article aims to identify the factors influencing freshmen’s speaking anxiety in Foreign Language for Specific Purpose (FLSP) class. The researcher conducted a case study with a descriptive qualitative approach. Moreover, 20 FLSP freshmen in the communication science department participated in this study. The data was collected using a close-ended and open-ended questionnaire of the Foreign Language Speaking Anxiety Scale (FLSAS) derived from Horwitz et al. (1986). The result exposed that the primary factor influencing freshmen speaking anxiety is “fear of negative evaluation,” followed by “test anxiety” and “communication apprehension.” This study ends with implications to assist the educator in fostering speaking and providing students with a positive environment to effectively support them in overcoming anxiety feelings.
Using Data-Driven Approach to Teach Descriptive Text: A Study in High School
Authors: Rifaldo Muhammad Pebriansyah , Maretha Annisa Laura , Pradita Intan
Published: January 2023

This paper aims to describe how data-driven learning can be applied in English classes when teaching descriptive text to senior high school students. This study was a self-observation involving 24 high school social studies students. The data were obtained from observation of student activities during learning, and the tasks carried out by students were in accordance with the basic competencies of the descriptive text material. The data were analyzed by conducting sorting the data and analyzing the sorted data by codifying and reporting the data. The results of this study showed that the application of data-driven learning with communicative learning methods can make students more confident in their abilities during the learning process. The use of data-driven learning is expected to increase students' motivation and learning abilities, especially in the field of writing.
EKSPRESI BERAGAMA KAUM MILENIAL DALAM MEMBANGUN PERILAKU MASYARAKAT (Studi Terhadap Majelis Rasulullah Provinsi Lampung)
Authors: Fathul Muin Fathul Muin , Budiman Arif
Published: January 2023

Penelitian ini untuk mengetahui ekspresi beragama yang dilakukan kaum milenial yang tergabung dalam komunitas Majelis Rasulullah Provinsi Lampung. Penilitian ini termasuk dalam penelitian lapangan (field research) yang datanya diperoleh dari literatur dan wawancara langsung dengan pengurus Majelis Rasulullah Provinsi Lampung. Penelitian ini menyimpulkan bahwa  Majelis Rasulullah Lampung merupakan komunitas yang berisi kumpulan umat Islam Bumi Ruwa Jurai. Dalam beragama, mereka berpaham Ahlus Sunah Wal Jamaah. Praktik keagamaan mereka tidak mengarah kepada ekstrimisme dan radikalisme. Di bawah kepemimpinan Habib Abdurrahman bin Ahmad Alydrus, baik pengurus dan anggota selalu menjaga ukhuwah Islamiah. Dalam dakwah, mereka mengutamakan cinta dan kasih sayang, melembutkan hati dan keluhuran budi pekerti, menggunakan metode dakwah bil lisan berupa ceramah, tabligh, khutbah baik di mimbar maupun melalui media sosial. Dalam setiap majelisnya selalu menanamkan nilai-nilai kebaikan seperti cinta kepada Allah dan Rasul, berbakti kepada orang tua, moderat dalam beragama dan mempererat persaudaraan.
KONSTRUKSI MOTIVASI DALAM PANDANGAN ISLAM
Authors: Tarmizi Ahmad , Panambaian Tubagus
Published: January 2023

Motivasi merupakan bagian penting dari keimanan. Motivasi termasuk gejala psikologis yang menjadikan manusia untuk bertindak sesuatu berdasarkan apa yang diyakin dan diketahuinya. Penelitian pada artikel ini mencoba untuk memberikan gambaran secara ringkas dan padat mengenai motivasi dari berbagai perpektif dan terutama menggunakan perspektif Islam untuk merealisasikan motivasi dengan ibadah. Peneliti menemukan bahwa motivasi berkaitan erat dengan keimanan yang mana iman ini adalah pengetahuan tertinggi pada manusia
MEMAHAMI KONSEP ISLAM REVISIONIS MUN’IM SIRRY
Authors: Rafii Muhammad
Published: January 2023

The argument of this article is that the revisionist Islamic ideas and concepts popularized by Mun'im Sirry in Indonesia is an academic work that invites Islamic scholars to re-examine Islamic sources in order to find historical truth. For Mun'im Sirry Islam believed by Muslims has not been able to distinguish between historical facts and theological beliefs. The findings of this study are that Mun'im Sirry supports several theses of previous revisionist scholars such as John Wansbourgh and Ignaz Goldziher regarding the many historical distortions, teachings and rituals of Muslims which are actually different from early Islamic practice. However, Mun'im Sirry has his own unique revisionist concept of Islam. One of the factors causing this bias is because Muslims accept Islamic sources as taken for granted, that Islam is a religion that has been perfected. An important point for disseminating revisionist Islamic ideas is that new facts and interpretations are very important to support the construction of a tolerant, dialogical attitude in order to create a religious community that can live side by side and work together.
MATERIALISME DAN ISLAM
Authors: Ramadan Willy , Fitriah Fitriah
Published: January 2023

The materialists tried to convince others that the cause of the growth and prevalence of materialism during the 18th and 19th centuries was the emergence of scientific theories and that it was the spread of science and technology that resulted in humanity being attracted in that direction. Muthahhari rejected this view. The growth of science or education has nothing to do with materialism. Materialism took the form of a school of thought during the eighteenth and nineteenth centuries. It was then that materialist ideas took the form of ideologies and many embraced them eagerly.
Obesity and life events: the hypothesis of psychological phenotypes
Authors: Rizzo Amelia
Published: January 2023

Psychological studies on obesity have focused on finding common traits in the population of people with obesity, such as personality traits. In contrast, in the field of medicine, it is pointed out that individuals with obesity can be very different from each other, e.g. in terms of their metabolic profile, which gives rise to different phenotypes. 

This article proposes a clinical and theoretical observation of the role of life events in the development of obesity. Obesity patients indeed report differentiated life and weight control histories. The proposal is to distinguish these types of patients into two psychological phenotypes at initial assessment, as surgical and post-surgical outcomes may differ. While from a mental health point of view, identifying these elements may be an indicator to send the patient to effective and targeted psychological treatments.
OUTCOME OF VESICOVAGINAL FISTULA REPAIR AT TERTIERY HOSPITAL: COHORT STUDY
Authors: Liarto Jason , Jufriady Ismy
Published: January 2023

Objective: This study aims to provide an evaluation of the outcome of patients with history of vesicovaginal fistula repair by assessing the success rate and complications that occur.  Material & Methods: This study was a retrospective cohort study to describe the etiology, approach, and outcome in patients undergoing vesicovagina fistula repair. We analyzed the complication with vesicovaginal fistula type, etiology and technique used.  Results: There were 10 vesicovaginal fistula patients, with mean age 33.4 ± 14.5 years. Both transabdominal and transvaginal approach were equally used. Sixty percent patient was successfully treated without complication. Forty percent patient with incontinence came with mild urinary incontinence and need further repair.  Conclusion: Both transvaginal and transabdominal approach were equally effective to repair fistula with relatively low complication rate and high successful rate.

Keywords: Vesicovaginal fistula, retrospective, transabdominal and transvaginal.
AN UNUSUAL CASE OF PENILE TUMOR: GIANT SIZED VERRUCIFORM XANTHOMA OF PENIS
Authors: Yogarama Aditya , Hendratno Josep Joko
Published: January 2023

Objective: This study aims to present a case of Verruciform Xanthoma (VX) on penile shaft. Case(s) Presentation: A 60 years old man was admitted to our hospital with a large sized (8cm) cauliflower like tumor on his penile shaft which started to appear 2 years prior to hospital admission. The tumor was continuously getting bigger during that period. The man did not feel any other signs and symptoms. Incision biopsy sample was taken and the histopathologic result was Verruciform Xanthoma. Then the patient took excision circumcision surgery. Discussion: Penile VX is a benign, asymptomatic, warty lesion that can occur in penile shaft, glans, coronal sulcus, and preputium. Its pathological mechanism is still unclear but the most accepted theories are mucocutaneous reaction to localized trauma and chronic inflammation. Due to its atypical appearance, it can be mistaken as other lesion, even a malignant one. Histopathological examination must be done to confirm diagnosis, and to plan the right treatment. We conduct excision and circumcision to compensate a wide skin loss and achieved satisfactory result. Conclusion: Penile VX can be mistaken as a malignant lesion, thus histopathological examination must be done to avoid over radical treatment. Excision and circumcision surgery for large sized penile VX achieve satisfactory result.

Keywords: Penile, verruciform xanthoma, tumor.
GIANT NON-FUNCTIONING ADRENOCORTICAL CARCINOMA
Authors: Fam Ivandy , Kasman Decky , Guntoro Dilino Ryan , Isdiyanto Septiadi
Published: January 2023

Objective: This study aims to report a case of a 51 year old male who was referred to our Department of Urology and was diagnosed with a nonfunctioning giant ACC. Case(s) Presentation: The case report describes a 51-year-old Indonesian man who presented to our department with complaints of persistent upper left abdomen discomfort, previously misdiagnosed as dyspepsia. He was diagnosed as having non-functioning adrenocortical carcinoma and underwent open adrenalectomy. Discussion: Although the patient is 51 years old and the tumor has grown to a signify cant size, no lymph node involvement or metastases was found and resection margins were found to be negative. In our patient, functional adrenal work-up results were normal. This has led us to suspect a non-functioning adrenal tumor. Metastatic work-up with CT cranial, chest, and bone survey were performed, with negative result. The biopsy result after resection confirmed the diagnosis of ACC. Conclusion: ACC is a rare aggressive tumor, malignant with poor prognosis. In our case, the non-secretory mass was diagnosed late by manifestation of mass effect symptoms in the upper left quadrant of the abdomen and was previously misdiagnosed as symptoms of dyspepsia. The functional work-up of adrenal masses helped in the determination of its non-functional status. Early diagnosis of ACC and early surgical excision helps in improving the overall survival rate of the patient.

Keywords: Non-functioning, adrenocortical carcinoma (ACC), adrenalectomy, case report.
PRIMARY DIFFUSE LARGE B CELL LYMPHOMA OF TESTICULAR : A CASE REPORT
Authors: Lionardi Stevan Kristian , Singgih Nicholas Andrian , Bagus Lutfi
Published: January 2023

Objective: To report our experience in treating a case of Testicular non-Hodgkin Lymphoma. Case(s) Presentation: A 55-year-old man came to the urology outpatient clinic with complaints of an enlarged left painless testicle that was lumpy and heavy.  Urological examination found left unilateral testicle enlargement testicle, the size measured 10x7x7 cm with firm borders, solid consistency, and no tenderness. The patient then was treated with left orchiectomy. Histology and Immunohistochemical examination found non-Hodgkin B cells (CD20+) high grade, non-GCB. Discussion: In this case, the patient was treated with orchiectomy followed by a CHOP chemotherapy regimen. However, there was an unusual presentation due to the suspicion of metastases through the findings of a tender lump in the left inguinal region which was further confirmed by histological and immunohistochemical examination. Conclusion: Primary testicular lymphoma with a subtype of DLBCL (Diffuse Large B-Cell Lymphoma) is a rare disease. Orchiectomy is the initial treatment option for Testicular non-Hodgkin Lymphoma followed by combination therapy of chemotherapy to improve the prognosis.

Keywords: Orchiectomy, testicular lymphoma, testicular tumors.
RENAL ARTERY THROMBOSIS SECONDARY TO BLUNT ABDOMINAL TRAUMA: RARE CASE SERIES
Authors: Syarief Ahmad Nurfakhri , Rizaldi Fikri
Published: January 2023

Objective: This study aims to report the possibility of non-operative management (NOM) as a Renal artery thrombosis (RAT) treatment. Case(s) Presentation: In this series, we reported 3 cases of unilateral RAT secondary to blunt abdominal trauma treated with NOM, where patient had complete bed rest, close observation, laboratory tests, and serial imaging. During a first-month follow-up, hypertension, renal abscess, persistent flank pain, or impairment of renal function were not found in the patients. However, after a one-year follow-up, an atrophic kidney appeared due to RAT in one of our cases. Discussion: RAT secondary to blunt abdominal trauma is rare. However, the management of RAT is still controversial. Renal preservation with NOM possesses reasonable success because the risk of complication does not exceed that of revascularization, and is currently considered. Conclusion: NOM is considered a treatment option in the cases of unilateral RAT with good contralateral renal function. This treatment provides a minimal number of complications.

Keywords:  Renal artery thrombosis, non-operative management.
MEMPERKUAT KINERJA KARYAWAN DENGAN MEREDUKSI FAKTOR STRES DAN MEMBANGUN LINGKUNGAN KERJA YANG NYAMAN
Authors: Veritia Veritia
Published: January 2023

This study aims to determine and analyze the effect of work stress and physical work environment on employee performance at PT. Jet Technology Express (J&T Express) Ciledug Tangerang Drop Center Branch, either partially or simultaneously. The method used is descriptive quantitative. The sampling technique used saturated sampling where the entire population was used as a sample, in this study there were 55 respondents. Data analysis used validity test, reliability test, classic assumption test, regression analysis, coefficient of determination analysis, and hypothesis testing. The results showed that there was a positive influence between work stress and employee performance partially. Where is the simple linear regression equation Y = 16.243 + 0.678 X1 means that it has a positive effect, the reliability test r = 0.948 is included in the strong category, the coefficient of determination is 48.9% and the remaining 51.1% is influenced by other factors, the t test is tcount 7.115 > ttable 2.00665 then Ha is accepted and Ho is rejected. The results showed that there was a positive influence between the physical work environment and employee performance partially. Where is the simple linear regression equation Y = 31.298 + 0.328 X2 means that it has a positive effect, the reliability test r = 0.881 is included in the strong category, the coefficient of determination is 20.6% and the remaining 80.4% is influenced by other factors, the t test is tcount 3.706 > ttable 2.00665 then Ha is accepted and Ho is rejected. The results showed that there was a positive influence between the variables of work stress and the physical work environment on employee performance simultaneously, where the multiple regression equation Y = 15.932 + 0.805X1 +0.125X2 means a positive effect, the reliability test r = 0.956 is included in the strong category, the coefficient of determination of 50.1% and the remaining 49.9% which is influenced by other factors, the f test of fcount 26.134 > ftable 3.172 means that it can be concluded that the variables of work stress and physical work environment have a significant effect on employee performance.Keywords: Work Stress, Physical Work Environment, Employee Performance
PENGARUH CURRENT RATIO DAN DEBT TO EQUITY RATIO TERHADAP NET PROFIT MARGIN PADA PT JAPFA COMFEED INDONESIA
Authors: Nurwita Nurwita , Rahim Eka , Konefi Fitri
Published: January 2023

This study aims to analyze the effect of the variables Current Ratio, Debt to Equity Ratio, Net Profit Margin at PT Japfa Comfeed Indonesia Tbk 2012-2021. This type of quantitative research, quantitative research is research that does not focus too much on the depth of the data, the important thing is to be able to record as much data as possible from a large population, even though the research population is large but can easily be analyzed either through statistical or computer formulas so that solving research problems it is dominated by statistics. In this study the authors chose the research location at PT Japfa Comfeed Indonesia (JPFA) Tbk, the company has been listed on the Indonesia Stock Exchange. PT. Japfa Comfeed Indonesia (JPFA) is an agri-food company. Its core activities include the manufacture of animal feed, chicken farming, poultry processing and aquaculture. The company started commercial operations in January 1971. The research method used is quantitative and uses statistical analysis and financial ratios. This research was carried out in stages starting from preliminary studies, preparing proposals, collecting and collecting data, to processing data. Results of this Research.Keywords: Current Ratio, Debt to Equity Ratio, Net Profit Margin
EFFECT OF SOCIAL MEDIA ON BUYING INTEREST AND CONSUMER BUYING DECISIONS: A Systematic Literature Review
Authors: Budiyanto Arief , Pamungkas Ibrahim Bali , Praditya Alvin
Published: January 2023

This study describes how the development of consumer behavior research on social media, the types of research and objects on buying interest and buying decisions on social media, and the determining factors that determine this. All of them are summarized through a systematic literature review of 73 journals that are used as references. In collecting journals, the researcher used the PICO approach to formulate research questions and the use of protocols in the process of inclusion and exclusion of research journals. It was found that the quantitative research approach still dominates research with that theme, the object of research on beauty and fashion, websites and e-commerce, food and beverages, and services, which are the most widely discussed themes in reference journals, while the determinant factors that determine consumer buying interest in the media are, among others, attention, interaction, and communication of members of social media, as well as ease of access. These factors also increase consumer buying interest on social media, while in purchasing decisions, informative factors, consumer social media usage behavior, and convenience are factors that influence consumer buying interest and purchasing decisions on media. social.Keywords:   Systematic Literature Review, SocialMedia, Online Buying Interest, Online Purchase Decisions, Online Consumer Behavior
PENGARUH DIGITALISASI DAN DATA CENTRE TERHADAP KINERJA KARYAWAN PT.XYZ
Authors: Purwatiningsih Purwatiningsih
Published: January 2023

PT. XYZ, which is tasked with assisting companies in carrying out information activities, including specific information systems, general information, multimedia and opinion counters within the company, has a very important role in publicizing and disseminating various company activities and leadership policies throughout Indonesia. With limited employees who are superior, qualified, professional and competent in providing better public services, it is necessary to increase the quality and quantity of employees in carrying out their duties. One of the factors that influence the performance of PT. XYZ in this study is digitization. The purpose of digitization is to make it easier for employees to convey, provide, compile and explain information received by PT. XYZ to be processed and used as information suitable for consumption by the public. In carrying out its work, information systems require good data center support. This data center is big data for all levels of Company information, where all information can be accessed through the data center. The purpose of this study was to examine the effect of digitization and data center on the performance of PT. XYZ employees. The sample used in this study were PT. XYZ employees totaling 99 respondents. The sampling technique used is non-probability sampling, where not every respondent has the same opportunity to be sampled. The results in this study based on SPSS processing obtained the calculated t value for the digitization variable of 3.395 and the data center was 7.238, while the t table obtained was 1.661. This means that if t count > t table and the significance value is <0.05. So that it can be interpreted that there is an influence between digitalization and data center partially on performance. Based on the results of the f test, the calculated f value for the digitization and data center variables simultaneously is 54.697 while the f table obtained from the f table search is 3.091. So the results state that there is an influence between digitalization and the data center simultaneously on the performance of PT. XYZ employees. While the value of r2 = 0.533 which means that 53.3% of the performance variables can be explained by digitalization and the data center while the remaining 46.7% is influenced by other variables outside the model studied.Keywords: Digitization, Data Center, Performance, Employees, Management
Khazanah Islami (Khais): Inovasi Aplikasi Berbasis Mobile Sebagai Upaya Preventif Prokrastinasi Ibadah di Era Digital
Authors: Irmawati  , Aziz Ridha Abdul
Published: January 2023

Perkembangan teknologi informasi di era digital semakin maju dan berkembang pesat. Arus globalisasi semakin tidak terkendali, teknologi yang hakikatnya diciptakan untuk membuat hidup manusia menjadi semakin mudah dan nyaman. Namun tidak ada bidang kehidupan manusia yang bebas dari teknologi. Menurut Zalfa banyak orang yang mengaku Islam, tetapi melalaikan dan meremehkan kewajibannya sebagai umat Islam seperti melalaikan atau menunda waktu salat. Padahal salat merupakan salah satu kewajiban umat Islam yang harus ditunaikan. Permasalahan yang sering dijumpai dikalangan remaja adalah lebih senang menghabiskan waktu dengan hal yang tidak bermanfaat tanpa mengingat waktu. Oleh karena itu, penulis membuat sebuah solusi berdasarkan permasalahan yang ada dengan membuat sebuah aplikasi yang bernama Khazanah Islami: Inovasi Aplikasi Berbasis Mobile sebagai Upaya Preventif Prokrastinasi Ibadah di Era Digital. Metode yang digunakan Research and Development (R&B) sedangkan teknik pengumpulan data yang digunakan dalam penelitian ini adalah studi kepustakaan yang diambil dari buku, jurnal, maupun situs internet lima tahun terakhir yang berkaitan dengan objek penelitian dan internet searching. Aplikasi ini menyajikan fitur-fitur keislaman sebagai pengingat ibadah umat Islam sebagai upaya preventif prokrastinasi ibadah di era digital. Manfaat dari aplikasi Khazanah Islami yaitu sebagai solusi untuk mencegah terjadinya prokrastinasi ibadah di tengah aktivitas masyarakat yang sering melalaikan ibadah wajib sehingga aplikasi ini menjadi alternatif pengingat ibadah yang akan mendisiplinkan penggunanya dalam beribadah. Aplikasi ini juga dapat menambah wawasan keislaman seseorang karena disajikan fitur-fitur yang dapat diakses dengan mudah oleh pengguna.
Stratifikasi Terbuka Posisi Pekerja Hotel: Apakah Budaya Patriarki Ditegakkan?
Authors: Aulia Azzahra Almira
Published: January 2023

Permasalahan gender dan budaya patriarki bukanlah hal yang asing lagi. Gender merupakan proses keyakinan bagaimana laki-laki dan perempuan seharusnya bertindak, sehingga hal ini tidak dipengaruhi oleh faktor biologis melainkan dapat dipengaruhi oleh sosial, adat, dan budaya. Dunia kerja atau karir merupakan hal yang akan dilalui oleh setiap orang dalam hidupnya, baik itu bekerja secara mandiri maupun kelompok. Namun tidak semua jenis pekerjaan menerima berbagai jenis pekerja. Salah satu pekerjaan yang menerima berbagai jenis pekerja adalah hotel. Hotel memiliki lapisan struktur yang terdiri dari banyak orang dan posisi, termasuk pekerja wanita. Dunia kerja merupakan dunia yang keras bagi kaum wanita. Hal ini dikarenakan keterbatasan kesempatan yang diberikan kepada wanita. Tidak semua orang familiar dengan posisi pekerjaan yang ada di hotel, juga jarang sekali orang yang minat dalam bidang perhotelan. Tujuan dari penelitian ini adalah untuk mengetahui apakah posisi kerja di hotel membatasi wanita untuk berkarir, serta untuk mengetahui posisi apa saja yang bisa ditempati wanita bila bekerja di perhotelan. Untuk menunjang keberlangsungan penelitian ini, maka digunakan metode studi kasus untuk mengambil data dan informasi yang diperlukan. Teori yang digunakan dalam penelitian ini adalah termasuk dalam teori kepuasan kerja, yakni teori keseimbangan (equity theory). Teori ini cocok dengan penelitian tentang penempatan posisi kerja antara wanita dan pria, untuk melihat apakah keadilan pada posisi kerja di perhotelan sudah ditegakkan atau masih menggunakan budaya patriarki, dan melihat apakah segala posisi yang ada di perhotelan diperkenankan untuk melibatkan tenaga kerja wanita.
Konstruksi Mahasiswa Nonmuslim Kota Surabaya Terhadap Tren Lepas Pasang Jilbab di Media Sosial
Authors: Fitri Shafwa Ailsa , Machfud Fauzi Agus
Published: January 2023

Penelitian ini berfokus pada persepsi dari mahasiswa nonmuslim terhadap adanya trend lepas jilbab yang terdapat dalam media sosial. Pada masa ini media, sosial dapat mempengaruhi kehidupan setiap manusia yang menggunakannya. Media sosial juga menjadi tempat bagi setiap individu untuk mengekspresikan diri. Jilbab merupakan sebuah simbol penting dalam agama Islam bagi para pemeluknya. Dalam prakteknya masih ditemukan fenomena dari muslimah yang menggunakan jilbab dalam kehidupan sehari-hari, namun ketika di media sosial tidak menggunakan jilbab sebagai simbol penting dari agama islam. Penelitian ini menafsirkan perspektif dari mahasiswa nonmuslim dalam melihat fenomena tersebut. Tujuan dari Penelitian ini adalah untuk mengetahui pemahaman dari mahasiswa nonmuslim melihat fenomena tersebut yang dikaji melalui sosiologi agama. Menggunakan teori interaksi simbolik untuk melihat pemaknaan dari persepsi mahasiswa nonmuslim ketika melihat fenomena lepas pasang jilbab di media sosial. Metode yang digunakan dalam penelitian ini adalah metode dengan kualitatif dengan menggunakan pendekatan fenomenologi untuk menganalisis realitas dengan melihat pengalaman dari mahasiswa perempuan muslim kota Surabaya yang pernah melakukan lepas pasang jilbab di media sosial melalui teknik pengumpulan data berupa observasi dan wawancara. Hasil penelitian menunjukkan bahwa makna agama islam tetap tersampaikan dengan baik meskipun terdapat fenomena lepas pasang jilbab di media sosial.
Analisis Resepsi Milenial Terhadap Ageisme Pada Film Senior Year
Authors: Chumairo Nur Alfia , Indriastuti Yudiana
Published: January 2023

Film merupakan salah satu bentuk media komunikasi yang berisikan suatu pesan untuk disampaikan kepada khalayak. Namun penerimaan khalayak terhadap pesan tersebut tentunya akan berbeda sesuai dengan latar belakang masing-masing individu.Penelitian ini bertujuan untuk mengetahui pemaknaan khalayak yakni milennials tentang adanya ageisme di dalam film Senior Year. Adapun pada penelitin ini menggunakan metode penelitian berupa analisis resepsi milik Stuart Hall yang membagi penerimaan khalayak menjadi tiga kategori posisi, yakni; dominant hegemonic code, negotiated code dan opposittional code.  Teknik pengumpulan data yang digunakan peneliti berupa wawancara mendalam dengan informan yang telah memenuhi syarat ketentuan yang dibutuhkan di dalam penelitian ini. Dengan mengolah data dan menganalisis hasil wawancara mendalam terhadap penerimaan informan-informan tentang ageisme di dalam film Senior Year, menggunakan teori encoding-decoding milik Stuart Hall dengan keempat informan yang memiliki referensi dan pengalaman yang berbeda. Maka di dapatkan hasil bahwa informan pertama dan ketiga berada pada posisi dominant hegemonic code, informan kedua berada pada posisi negotiated code dan informan keempat berada pada posisis opposittional code.
Tathwiru Qomusul Jaibil ‘Arabiyyah (kamus santri baru level 3) Al-Mustakhdimah Ladaiya Ath-Thullab bi Ma’had Darul Mukhlishin Aceh Tamiang
Authors: Nidaul fitri Nidaul fitri , Fuji Astuti  , Rahmatun Nisak
Published: January 2023

Penelitian ini bertujuan untuk menghasilkan produk buku yaitu kamus praktis antonim kata bahasa Arab yang disusun berdasarkan teori kamus santri zainal abdillah al-iman dan Dzikir Umar Lc. Kamus ini dibuat dengan tujuan untuk digunakan sebagai kamus pendamping dalam pembelajaran bahasa arab dan diujicobakan pada siswa tsanawiyah VIII,dan untuk mengetahui efektivitasnya dalam pembelajaran bahasa arab.metode penelitian yang digunakan peneliti dalam penelitian ini adalah metode research and development (R&D) dengan menggunakan pendekatan kuantitatif dan kualitatif.penelitian dilakukan di SMP IT Darul mukhlishin Aceh Tamaing. Subyek penelitian adalah siswa VIII Tsanawiyah yang berjumlah 25 siswa.Prosedur pengembangan yang digunakan penulis terdiri dari 3 tahap yaitu.satu studi pendahuluan, yaitu melakukan observasi.dua,studi pengembangan kamus saku termasuk merencanakan prototype kamus saku makig,validasi oleh dosen ahli dan uji implementasi pada mahasiswa dan evaluasi kajian yaitu diseminasi.instrumen yang digunakan adalah berapa lembar angket yang digunakan untuk memvalidasi kamus saku oleh dosen ahli dan lembar angket respon mahasiswa.langkah-langkah yang dilakukan dalam pengembangan saku ini kamus merupakan studi pendahuluan dan studi pengembangan karena keterbatasan peneliti, pengembangan produk kamus bahasa arab saku hanya sampai pada tahap studi pengembangan yaitu konseptual dan empiris

Kata Kunci: Pengembangan, kamus saku arab (antonim)
Tax and foreign exchange factors of inequality (To posing a problem)
Authors: Tanasova A. S. , Sokolova E. Y. , Shandra I. G. , Chigireva A. V.
Published: January 2023

The high level of income inequality of the population is a long-term problem in the world. The pandemic of 2020 and the growth of geopolitical tensions in 2022 increase the urgency of finding its solution. Inequality is a multifaceted phenomenon determined by various factors — from differences in the structure of economies to the specifics of the mentality and traditions of a particular state. As a result, there are no unified approaches to reducing inequality. This article analyzes the relationship of income inequality in Russia with the parametersof fiscal policy and the ruble exchange rate at different stages of economic development. It is shown that in certain periods taxes are connected differentlywith income inequality of the population in Russia. The important role of social spending in its reducing is shown; such dependence may be explained by the ruble exchange rate and its linkages with the budget policy. The article is setting stage for further analysis of the problem.