bluuebunny/crossref_metadata_2025 huggingface dataset:
GEGVIC: A workflow to analyze Gene Expression, Genetic Variations and Immune cell Composition of tumor samples using Next Generation Sequencing data
Authors: Arqués Oriol , Faidherbe Solen , Bassaganyas Laia
Published: January 2025

Background.
The application of next-generation sequencing techniques for genome and transcriptome profiling is to build the main source of data for cancer research. Hundreds of bioinformatic pipelines have been developed to handle the data generated by these technologies, but their use often requires specialized expertise in data wrangling and analysis that limit many biomedical researchers. Providing easy-to-use, yet comprehensive and integrative open-source tools is essential to help wet-lab and clinical scientists feel more autonomous in performing common omics data analysis in cancer research.
Results.
Here, we present GEGVIC, an R tool to easily perform a set of frequently used analyses in cancer research, including differential gene expression, genomic mutations exploration and immune cell deconvolution using minimally processed human/mouse genomic and transcriptomic sequencing data. GEGVIC is designed as a modular pipeline that combines a variety of widely used available methods distributed in three principal modules (Gene Expression, Genomic Variation and Immune Composition), which run independently and include several visualization tools.
Conclusions.
In summary, GEGVIC provides a simple, powerful and highly flexible workflow for researchers to process and interpret tumor transcriptomic and genomic data while decreasing or eliminating coding burden and facilitating efficiency for inexperienced bioinformatics users. GEGVIC R package instructions and source code are published on Github (https://github.com/oriolarques/GEGVIC).
M5-brane prongs, string soliton bound states and wall-crossing
Authors: Gupta Varun , Narayan K.
Published: January 2025

We study Abelian M5-brane field configurations representing BPS bound states of self-dual string solitons whose locations correspond to the endlines of M2-branes ending on the M5-branes. The BPS equations are obtained from appropriate Bogomolny completion of the effective Abelian low energy functional with two transverse scalars, using two vectors representing the directions along which these endline strings extend. Then we impose boundary conditions on the scalars near the string soliton cores. This leads to a molecule-like equilibrium structure of two non-parallel string solitons at fixed transverse separations, with the M5-brane “prong” deformations comprising two “spikes”, each shaped like a ridge. The resulting picture becomes increasingly accurate as one approaches the wall of marginal stability, on which these states decay. There are various parallels with wall-crossing phenomena for string web configurations obtained from D3-brane deformations.
HOW MANY PREGNANCIES ARE ALLOWED AFTER FERTILITY PRESERVING MANAGEMENT OF ATYPICAL ENDOMETRIAL HYPERPLASIA?
Authors:   MBCHB-Tanta University, Egypt, MD-Ain Shams University, Egypt., Saad Hassanin Ebtessam ,   Consultant Obstetrics and Gynecology, Prime Hospital, Dubai.
Published: January 2025

Atypical endometrial hyperplasia,with fertility preserving management by hormonal IUS,and oral progesterone, natural conception three times,allowed for how many pregnancies before hysterectomy? To reduce the incidence of endometrial cancer.
State Hegemony in the Campaign of Religious Moderation in Higher Education (a Study at UIN Walisongo Semarang and UIN Raden Mas Said Surakarta)
Authors: Muhammad Hasyim , Naili Ni'matul Illiyyun
Published: January 2025

Religious radicalism in the university has recently reached a serious level. Not a few academics are involved in this understanding and show extreme attitudes both at the level of action and narrative. Since 2019, the Ministry of Religious Affairs has been committed to strengthening religious moderation. These efforts can be seen concretely in the preparation of Religious Moderation books, counseling activities, the formation of educational curriculum, and the establishment of the House of Religious Moderation in universities. PTKIN as the long arm of the Ministry of Religious Affairs has a strategic role in mainstreaming religious moderation in Indonesia. This qualitative study took two PTKIN in Central Java, UIN Walisongo Semarang and UIN Raden Mas Said Surakarta. Using a descriptive narrative approach, this study aims to determine the basis of the argumentation for mainstreaming religious moderation, identify activities initiated by PTKIN, and the practice of state hegemony through the Ministry of Religious Affairs in this effort. The results of this study indicate that UIN Walisongo Semarang and UIN Raden Mas Said Surakarta have theological and cultural argumentation bases in mainstreaming religious moderation. Both campuses have initiated activities both academic and non-academic in the implementation of religious moderation. In addition, the state through the Ministry of Religious Affairs seems to be aggressive in preventing radicalism and extremism by giving a mandate to PTKIN in mainstreaming religious moderation which seems to indicate that Islam is separate from the value of moderation.
Mekânda Varoluşun Betimlenmesi Üzerine Bir Analiz: Mr. Nobody Filmi
Authors: Sofuoğlu Demirbaş Ümran , Tuzcuoğlu Berrin , Bal Havva Beril
Published: January 2025

Mekân, fiziksel sınırları olan ve insan gereksinimlerini karşılayan bir boşluk olmanın ötesinde yaşamın birçok boyutuyla ilgili izleri taşıyarak yaşanmışlıkları içerir. Martin Heidegger ise mekânı, insanın dünya içinde var olma durumunun temel boyutu olarak nitelendirmektedir. İnsan varoluşunu anlamlandıran dünyaya, nasıl ve nereden geldiğini bilmemektedir ve yaptığı seçimler sayesinde dünyadaki konumunu, içinde bulunduğu durumları değerlendirme imkânı bulmaktadır. Seçimlerinde yapacağı küçük değişiklikler ise beraberinde büyük değişimler getirmektedir. Çalışmada; 2009 yılında Jaco Van Dormael’in yönetmenliğini yaptığı, boşanan anne ve babası arasında bir tercih yapması gereken dokuz yaşındaki çocuğun yaptığı seçimlere göre değişen yaşam serüvenleri anlatılan Mr. Nobody filminde gerçekleşen farklı olasılıklar üzerinden kurgulanan mekânlarda betimsel analiz çalışması yapılarak, Heidegger’in varoluşçu perspektifinden incelenmektedir. Sinema, mimarlık ve felsefe etkileşiminden yola çıkarak hazırlanan çalışmada; Heidegger’in felsefesinin mekânlarla desteklendiği, her olasılıkta mekân karaktere göre şekillenirken karakterin de mekânla var olduğu sonucuna ulaşılmıştır.
Análise da produção técnico-científica dos bolsistas de produtividade CNPQ em Educação Física no quadriênio 2017-2020
Authors: Moreira Caetano Pinto Guilherme , Archanjo de Freitas Júnior Miguel , Marino Favero Giovani , Pedroso Bruno
Published: January 2025

O objetivo do presente estudo é analisar o perfil sociodemográfico e a produção técnico-científica dos bolsistas de produtividade do Conselho Nacional de Desenvolvimento Científico e Tecnológico, na área de Educação Física, no período de 2017 a 2020. Para tal, obteve-se a lista dos pesquisadores da área da Educação Física com bolsa de produtividade através de uma consulta à página eletrônica do CNPq e aos seus respectivos currículos lattes na Plataforma Lattes do CNPq. A contabilização dos dados registrados nos currículos de todos os bolsistas ocorreu com auxílio do software scriptLattes v8.10. Verificou-se que: [1] Os bolsistas de produtividade no quadriênio 2017-2020 têm como perfil sociodemográfico majoritário ser pesquisadores do sexo masculino, da região Sul e Sudeste, e que pesquisam a temática fisiologia do exercício, atividade física e saúde e treinamento desportivo; [2] Os pesquisadores publicam a maioria de seus artigos em periódicos científicos; [3] Os pesquisadores com BP publicaram a maior parte de seus trabalhos em periódicos com Qualis A1 e A2 e/ou com JCR; [4] As redes de colaborações representam uma vantagem competitiva e são um fator imperativo dentro do grupo de bolsistas de produtividade. Conclui-se que os bolsistas de produtividade da área de Educação Física apresentam atividade acadêmica condizente com os critérios de concessão de BP.
Limits of liability of the carrier under the contract of carriage by road transport
Authors:   Murad Sh. Mazanaev Dagestan State University, Mazanaev Murad Sh. , Melnikov Alexander A. ,   Alexander A. Melnikov Dagestan State University
Published: January 2025

В статье рассматриваются вопросы разграничения пределов ответственности пере-возчика на автомобильном транспорте в рамках договорных отношений. Особое внимание уделяется ответственности субъектов таких правоотношений при перевозке грузов и при пассажирских перевозках. В рамках исследования проводится комплексный анализ положений главы 40 ГК РФ, в частности, статей 784, 785, 786, а также специального законодательства в области договора поставки. Кроме того, в работе задействован большой объем судебной практики по конкретным делам и обобщающие акты высших судебных инстанций. Цели данной статьи – выяснить и четко обозначить пределы ответственности перевозчика в каждом представленном случае договора, разобрать специфические особенности и правовую природу такой ответственности, выявить проблемы ее определения на практике, установить причины возникновения таких проблем, а также попытаться найти возможные пути их решения.
On some problems of legal regulation of the principles of administrative proceedings
Authors:   Igor N. Ivanenko Kuban State University, Ivanenko Igor N. , Mitashova Anastasia A. ,   Anastasia A. Mitashova Kuban State University
Published: January 2025

Авторы исследования акцентируют внимание на ряде законодательных несовершенств в области принципов административного судопроизводства. Поднимается вопрос о целесообразности выделения в КАС РФ отдельной статьи, содержащей перечень принципов КАС РФ. Авторы отмечают нецелесообразность выделения лишь ряда некоторых принципов и невнесения в перечень принципов, отраженных в других нормах КАС РФ. Выдвигается идея о том, чтобы упразднить ст. 6 КАС РФ вовсе, либо дополнить ее всеми иными принципами, «разбросанными» в тексте кодифицированного акта. Затрагивается проблема недоработки законодателем принципа состязательности и равноправия сторон при активной роли суда. Авторы акцентируют внимание на расхождении наименование принципа в ч. 7 ст. 6 КАС РФ и ст. 14 КАС РФ. В исследовании авторы приходят к выводу о необходимости отражения в тексте КАС РФ дефиниции «активная роль суда» как в ч. 7 ст. 6 КАС РФ, так и в ст. 14 КАС РФ. При этом, по мнению авторов, важным аспектом также выступает необходимость во внесении дополнений в ст. 14 КАС РФ, с обязательной правовой регламентацией «активной роли суда».
Some of the issues of reforming criminal legislation in terms of enhancing the fight with latent crime
Authors:   Rasul M. Akutaev Dagestan State University, Akutaev Rasul M. , Magomedov Kh.O. ,   Kh.O. Magomedov Dagestan State University
Published: January 2025

В статье рассматриваются вопросы реформирования уголовного законодательства с целью усиления борьбы с латентной преступностью. Актуальность статьи обусловлена необходимостью противодействовать реальной преступности. Автором акцентируется внимание на том, что наблюдаемая в последние годы тенденция заметного снижения показателей зарегистрированной преступности про-исходит за счет повышения латентной ее части. Говорится, что меры уголовно-правового воздействия в отношении лиц, преступивших уголовный закон, в первую очередь, зависят от характера и степени общественной опасности совершенного преступления. Обосновывается идея о том, что реформирование уголовного законодательства, в частности, включение в него такого института, как уголовный проступок, и проведение определенных организационно-управленческих преобразований, способны активизировать борьбу с латентной преступностью, особенно с наиболее многочисленной ее составляющей, которая представлена преступлениями небольшой тяжести. Делается вывод о том, что в борьбе с латентной преступностью существенный потенциал заложен в самом уголовном законодательстве, совершенствование которого может способствовать заметной ее активизации. Предложено разработать и опубликовать для обсуждения Концепцию нового Уголовного кодекса Российской Федерации.
Administrative discretion: conceptual and categorical apparatus
Authors:   Elvina E. Ablyakimova Crimean branch of the Federal State Budgetary Educational Institution of Higher Education RGUP, Ablyakimova Elvina E.
Published: January 2025

В статье проводится ретроспективный, а также теоретико-правовой и понятийно-категориальный анализ такого правового феномена как административное усмотрение. При этом так-же делается акцент на этимологическом анализе данного правового феномена. Автором исследуются взгляды зарубежных ученых, изучающих административное усмотрение в целом, в том числе в ретроспективе. Говорится, что институт административного усмотрения имеет непосредственное отношение к публично-управленческой сфере в контексте реализации субъектом публично-административной деятельности своих полномочий и определения советующего вектора при выборе из ряда возможных вариантов действий по своему усмотрению. Отсутствие в настоящее время нормативно урегулированной дефиниции «административное усмотрение» в науке административного права вызывает достаточно активную дискуссию, в рамках которой представлено множество авторских точек на исследуемое явление. В юридической литературе до сих пор не сложилось единого подхода к доктринальному определению административного усмотрения. Анализ имеющихся в юридической литературе различных концепций и теорий приводит к выводу о том, что дефиниция «усмотрение», выступающая в качестве определённой меры свободы субъекта правоприменения при выборе варианта решения, встречается в совокупности с другими терминами, например, судейское усмотрение, связывая его таким образом с областью применения. Таким образом, административное усмотрение исследователи рассматривают как власть, полномочия, деятельность, степень свободы, юридическую возможность, целесообразность, способ правотворчества, его механизм при реализации нормы. В итоге автор формулирует следующую дефиницию для юридической категории «усмотрение»: это – возможность для конкретного уполномоченного субъекта, используя интеллектуальный инструментарий, осуществить строго на основе норм права в своем интересе или в интересах третьих лиц конкретный вариант юридически значимого поведения в границах, установленных нормами права, а применительно к административному усмотрению: это – возможность для конкретного уполномоченного субъекта, используя интеллектуальный инструментарий, осуществить строго на основе норм административного права в своем интересе или в интересах третьих лиц конкретный вариант юридически значимого поведения в границах, установленных нормами административного права.
Analysis and evaluation of the law enforcement activities of the customs authorities of the Russian Federation
Authors:   Zukhra-Khanum T. Abusufyanova Dagestan State University, Dagestan State Technical University, Abusufyanova Zukhra-Khanum T.
Published: January 2025

Таможенные органы РФ призваны имеющимися у них средствами и присущими им методами обеспечивать экономическую безопасность государства. Важную роль в системе методов обеспечения экономической безопасности играют методы правоохранительной деятельности. На основе данных статистики, мнений ученых и специалистов в статье проведен анализ правоохранительной деятельности таможенных органов по различным направлениям, предложены направления ее совершенствования. При подготовке работы были использованы следующие методы исследования: статистический, анализ, синтез, системный подход, сравнительно-правовой.
Wopke de Jong: fan hege retoryk yn it Nederlânsk nei Nederlânske oersettingen fan klassiken en folksaardich Frysk
Authors: Breuker Philippus
Published: January 2025

Wopke de Jong (1799-1852) began his poetic career by writing poems in Dutch. In time, he joined the emerging Frisian literature of his time. As well as continuing to write highly rhetorical Dutch and Frisian poetry, he eventually turned to writing popular entertainment in Frisian. His rhetoric was based on a deep knowledge of the Bible and the classics. De Jong’s new orientation shows the strong position of the Frisian language at that time. Wopke Eekhoff had helped him along the way in 1832, and around 1845 de Jong took advantage of the rapidly growing opportunities for publishing in Frisian. He probably did not do so wholeheartedly, for in 1844 he had tried to found his own Dutch literary journal. Towards the end of his life he also began to write poetry in Latin.
Mapping the Landscape of Digital Health Intervention Strategies: 25-Year Synthesis
Authors: Liu Shiyu , Ma Jingru , Sun Meichen , Zhang Chao , Gao Yujing , Xu Jinghong
Published: January 2025

Background

Digital health interventions have emerged as promising tools to promote health behavior change and improve health outcomes. However, a comprehensive synthesis of strategies contributing to these interventions is lacking.

Objective

This study aims to (1) identify and categorize the strategies used in digital health interventions over the past 25 years; (2) explore the differences and changes in these strategies across time periods, countries, populations, delivery methods, and senders; and (3) serve as a valuable reference for future researchers and practitioners to improve the effectiveness of digital health interventions.

Methods

This study followed a systematic review approach, complemented by close reading and text coding. A comprehensive search for published English academic papers from PubMed, Web of Science, and Scopus was conducted. The search employed a combination of digital health and intervention-related terms, along with database-specific subject headings and filters. The time span covered 25 years, from January 1, 1999, to March 10, 2024. Sample papers were selected based on study design, intervention details, and strategies. The strategies were identified and categorized based on the principles of Behavior Change Techniques and Behavior Strategies.

Results

A total of 885 papers involving 954,847 participants met the eligibility criteria. We identified 173 unique strategies used in digital health interventions, categorized into 19 themes. The 3 most frequently used strategies in the sample papers were “guide” (n=492, 55.6%), “monitor” (n=490, 55.4%), and “communication” (n=392, 44.3%). The number of strategies employed in each paper ranged from 1 to 32. Most interventions targeted clients (n=844, 95.4%) and were carried out in hospitals (n=268, 30.3%). High-income countries demonstrated a substantially higher number and diversity of identified strategies than low- and middle-income countries, and the number of studies targeting the public (n=647, 73.1%) far exceeded those focusing on vulnerable groups (n=238, 26.9%).

Conclusions

Digital health interventions and strategies have undergone considerable development over the past 25 years. They have evolved from simple approaches to sophisticated, personalized techniques and are trending toward multifaceted interventions, leveraging advanced technologies for real-time monitoring and feedback. Future studies should focus on rigorous evaluations, long-term effectiveness, and tailored approaches for diverse populations, and more attention should be given to vulnerable groups.
Effectiveness of the User-Centered “Healthcare CEO” App for Patients With Type 1 Diabetes Transitioning From Adolescence to Early Adulthood: Protocol for a Randomized Controlled Trial (Preprint)
Authors: Chiang Yueh-Tao , Yu Hsing-Yi , Tsay Pei-Kwei , Chen Chi-Wen , Chang Chi-Wen , Hsu Chien-Lung , Lo Fu-Sung , Moons Philip
Published: January 2025

BACKGROUND

Young patients aged 16 to 25 years with type 1 diabetes (T1D) often encounter challenges related to deteriorating disease control and accelerated complications. Mobile apps have shown promise in enhancing self-care among youth with diabetes. However, inconsistent findings suggest that further evidence is necessary to confirm the effectiveness of app-based interventions.

OBJECTIVE

This study aims to evaluate the effectiveness of the Healthcare CEO app in patients with T1D transitioning from adolescence to early adulthood.

METHODS

A 2 arms, double-blind, randomized controlled trial will be conducted over a 9-month period, with strategies designed to enhance treatment fidelity. The study expects to enroll 96 patients with T1D, aged 16 to 25 years. Participants will be randomly assigned to either the experimental or control group through central randomization. The intervention will be implemented using the Healthcare CEO app, which consists of 11 interfaces. The research will compare differences in disease control outcomes, confidence in self-management, self-care behaviors, emotional distress, quality of life, and specific diabetes-related knowledge between the 2 groups at baseline and 3, 6, and 9 months after intervention. Additionally, changes within the experimental group will be analyzed before and after the intervention.

RESULTS

The study was funded in August 2020. It was originally scheduled from August 2020 to July 2022 but was interrupted by the COVID-19 pandemic after enrolling 38 participants, with preliminary results anticipated for publication by November 2024. Recruitment resumed in August 2023, with findings expected to be finalized by July 2025.

CONCLUSIONS

The Healthcare CEO app is a comprehensive solution tailored specifically for individuals with T1D transitioning from adolescence to early adulthood. This innovative app has the potential to improve the quality of care for adolescents with T1D during this critical stage and may serve as valuable evidence in support of app-based intervention strategies.

CLINICALTRIAL

ClinicalTrials.gov NCT05022875; https://www.clinicaltrials.gov/study/NCT05022875

INTERNATIONAL REGISTERED REPORT

DERR1-10.2196/59871
Reliability and Quality Assessment of Internet Videos as Guidance for Dietary Weight Loss Intervention: A Cross-Sectional Study in China (Preprint)
Authors: Chen Xiaohong , Zhou Shiqi , Zhang Yongjian , Zhong Qianqian , Sun Fengqin , Xu Rui , Sun Zhongli , Sun Junying , Yang Lin , Yan Shiqi , Zhang Qianle , Xie Zhuoxian , Yu Hanyi , Xu Yanwu
Published: January 2025

BACKGROUND

Obesity, a chronic disease affecting nearly all physiological functions, poses severe public health challenges by increasing the risk of conditions like diabetes, cardiovascular diseases, and depression. Managing obesity typically involves altering energy balance, with dietary interventions emerging as an effective and sustainable weight management approach. As internet usage surpasses 4 billion globally, many individuals now turn to online platforms for health information, with video content on platforms like TikTok gaining significant popularity for its accessibility and engagement. However, the quality of such content varies widely. In China, platforms like TikTok, BiliBili, and Kwai dominate health information dissemination, yet limited studies have evaluated the reliability of their dietary weight loss video content.

OBJECTIVE

Our study aims to assess the reliability and quality of the information in Chinese videos on dietary weight loss shared on the BiliBili, TikTok, and Kwai, three video–sharing platforms.

METHODS

We collected the top 100 dietary weight loss videos on BiliBili, TikTok, and Kwai in February 2024 and evaluated the information quality and reliability of the videos using the Global Quality Score (GQS) and mDISCERN. We also analyzed the correlation between video quality and video characteristics.

RESULTS

The average GQS scores for dietary weight loss videos on BiliBili, TikTok, and Kwai are 2.04, 1.81, and 1.7, respectively, while the average mDISCERN scores are 2.01, 1.81, and 1.73. The median scores for both GQS and mDISCERN across the three platforms are 2. Although BiliBili’s GQS and mDISCERN scores are higher than those of Kwai and TikTok (GQS: P<0.01, P=0.02; mDISCERN: P=0.02, P=0.08), none of the platforms have exceeded a score of 3, indicating that the quality and reliability of dietary weight loss videos on BiliBili, TikTok, and Kwai are all quite poor. Additionally, our study identified several significant positive correlations: the GQS score was positively correlated with video duration (r=0.41, P<0.01), as was the mDISCERN score (r=0.32, P<0.01). Strong positive correlations were also observed between the number of likes and favorites (r=0.90, P<0.01), likes and comments (r=0.92, P<0.01), as well as favorites and comments (r=0.86, P<0.01).

CONCLUSIONS

Our research found that although the GQS and mDISCERN scores of BiliBili were higher than those of TikTok and Kwai, the final scores of the three platforms did not exceed 3 points, indicating that the video quality of the three diet video websites was low. Video social media platforms should establish relevant policies to supervise and review the publication of medical science popularization videos, providing reliable sources of information for public health.
Quality Assessment of Health-related Information on Social Media During a Public Health Crisis (Preprint)
Authors: Haghighi Rozita , Farhadloo Mohsen
Published: January 2025

BACKGROUND

The quality of health information on social media is a major concern, especially during the early stages of public health crises. While the quality of the results of the popular search engines related to particular diseases have been analyzed in the literature, the quality of health-related information on social media such as X/Twitter during the early stages of a public health crisis has not been addressed.

OBJECTIVE

This study aims to evaluate the quality of health-related information on social media during the early stages of a public health crisis.

METHODS

A cross-sectional analysis was conducted on tweets related to health in the early stages of the most recent public health crisis (COVID-19 pandemic). The study analyzed the top 100 websites that were most frequently retweeted in the early stages of the crisis, categorizing them by content type, website affiliation, and exclusivity. Quality and reliability were assessed using the DISCERN and JAMA benchmarks.

RESULTS

Our analyses showed that 95% of the websites met only 2 of the 4 JAMA quality criteria. DISCERN scores revealed that 81% of the websites were evaluated as low scores, and only 11% of the websites were evaluated as high scores. The analysis revealed significant disparities in the quality and reliability of health information across different website affiliations, content types, and exclusivity.

CONCLUSIONS

This study highlights a significant issue with the quality, reliability, and transparency of online health-related information during a public health challenge. The extensive shortcomings observed across frequently shared websites on Twitter highlight the critical need for continuous evaluation and improvement of online health content during the early stages of future health crises. Without consistent oversight and improvement, we risk repeating the same shortcomings in future, potentially more challenging situations.
Development and Validation of Clinical Predictive Models for Coronary Heart Disease in Diabetic Patients (Preprint)
Authors: Tang Jie , Li Jin , Zhang Zheqing , Dong Jiancheng , Liu Zhangsuo , Li Lianxi , Wu Huiqun
Published: January 2025

UNSTRUCTURED

Background: Coronary heart disease (CHD) has emerged as one of the gravest complications associated with type 2 diabetes mellitus (T2DM), underscoring an urgent demand for affordable and effective screening tools. This study sought to construct predictive models for CHD utilizing machine learning (ML) techniques tailored for T2DM patients, leveraging observational data extracted from electronic health records (EHR).
Methods: De-identified electronic health records (EHRs) encompassing 1,882 diabetic patients were acquired from the Endocrinology Department of the Shanghai Sixth People’s Hospital, affiliated with Shanghai Jiao Tong University, as well as from the First Affiliated Hospital of Zhengzhou University. A variety of ML models, including logistic regression (LR), decision tree (DT), random forest (RF), eXtreme gradient boosting (XGBoost), AdaBoost, ensemble tree, and Naïve Bayes model (NBM), were employed to conduct cardiovascular disease (CVD) predictions within the KNIME environment. Performance assessments were grounded in the Area Under the Receiver Operating Characteristic (AUC) through cross-validation, with external validation executed on a separate dataset from another hospital comprising 63 T2DM patients diagnosed with CHD to verify the efficacy of the predictive models.
Results: A 17-feature set was discerned through the leave-one-out (LOO) selection method based on their significance scores. Atherosclerosis, cardiovascular stenosis, and serum uric acid levels emerged as the most pivotal factors influencing the precision of the predictive model. The random forest, AdaBoost, and XGBoost algorithms demonstrated the highest average AUC values among all tested methodologies (0.878, 0.877, and 0.875, respectively). External validation further corroborated these findings, revealing commendable consistency.
Conclusions: Models grounded in machine learning have the potential to accurately predict CHD in T2DM patients, warranting further clinical validation.
Tiempos de migrar: la educación de la niñez migrante haitiana y centroamericana en la frontera noroeste de México
Authors: Vargas-Valle Eunice D. , López Castro Eder Orlando
Published: January 2025

El objetivo de este artículo es analizar la situación de la educación de la niñez migrante internacional proveniente de Haití y de Centroamérica que residía en Tijuana, México, en 2022, la mayoría en espera de refugio en Estados Unidos. Se usa metodología mixta que integra el análisis de una encuesta dirigida a migrantes de estos orígenes con 6 o más meses en Tijuana, así como entrevistas a migrantes de estos orígenes y a actores clave. Como parte de los resultados se encuentra una muy baja inserción escolar - incluso para aquellos migrantes que se ubican fuera de albergues-, y se identifican  un conjunto de barreras motivacionales, económicas, culturales y sociales para la inserción escolar de estos migrantes, así como las acciones estatales y de organizaciones civiles para la escolarización y el desarrollo de aprendizajes de estas poblaciones.
Validación de un instrumento para evaluar la difusión, divulgación y uso de productos comunicativos científicos para la enseñanza-aprendizaje en educación superior
Authors: Leon Duarte Gustavo Adolfo , Contreras Cázares Carlos René , Meneses Jurado Erika Carolina
Published: January 2025

Con una tradición de al menos seis décadas, en Norteamérica la difusión y la divulgación científica ha sido vista como una responsabilidad directa de la academia y de la ciencia, pese a que son escasos los modelos que aspiran a medir su impacto. Este texto expone el diseño y validación de un instrumento para evaluar la práctica académica de comunicación científica en el que convergen los factores de difusión, divulgación y práctica docente en el uso de productos comunicativos científicos para la enseñanza-aprendizaje. El instrumento se integró a cuatro escalas y 33 indicadores sobre una muestra de 235 docentes investigadores de 16 universidades ubicadas en México, Estados Unidos de América y Canadá, principalmente. Los resultados de las pruebas de las correlaciones mostraron una validez convergente con coeficientes altos y significativos. Para  estudios subsecuentes, se propone un modelo ampliado con la finalidad de que sirva como base para diversificar diseños y alcances de investigación
Análisis de necesidades para la formación en línea de profesores de lenguas extranjeras en México
Authors: Valerdi Zárate Julio César
Published: January 2025

La evolución del uso educativo de las TIC y las dinámicas pospandémicas de estudio y trabajo han agudizado la necesidad de desarrollar procesos educativos en línea y a distancia. La formación de profesores de lenguas extranjeras no es la excepción, como lo refleja el contexto de la Escuela Nacional de Lenguas, Lingüística y Traducción (ENALLT) ante la creciente demanda por parte de personas con necesidades formativas que esta escuela no puede satisfacer y que no parecen abordarse en otras instituciones. En función de lo anterior, se realizó un análisis de necesidades de la actual oferta de formación y actualización en línea de profesores de alemán, francés e inglés en México. Los resultados revelan limitaciones de naturaleza económica, geográfica, institucional, formativa y lingüística que obstaculizan el acceso a formación y actualización docente de profesores de diferentes puntos del territorio nacional. El conocimiento de dichas limitaciones puede informar la toma de decisiones para desarrollar nuevas propuestas de formación docente en línea en diversos contextos.
Fantasmas del canon cubano. Invisibilización de escritoras fantásticas en los años sesenta: María Elena Llana y Esther Díaz Llanillo
Authors: Sánchez Aramburu Patricia
Published: January 2025

El presente artículo trata la exclusión en el canon de escritoras en la década de losaños sesenta en Cuba y explica, a través del análisis literario de seis cuentos de María Elena Llanay Esther Díaz Llanillo, el uso del género fantástico para crear universos femeninos en los que lamujer y sus problemas para construir una identidad propia sin los condicionamientos socialesestán en el centro de la reflexión. El objetivo principal es recuperar la obra de los años sesenta deestas dos escritoras pioneras del género fantástico en Cuba y reivindicar su contenido político yemancipatorio, cuestionado en su época por una visión androcéntrica que sóloapreció en estostextos evasión y divertimento
La historia amazónica a través de la narración arqueológica
Authors: Silva Euzebio Douglas Fabian
Published: January 2025

El presente texto propone una reconstrucción sintética de la historia de la narracióncientífica atribuida a la amazonia brasileña, analizando para esto un conjunto de enunciadosproducidos particularmente en el campo arqueológico. El objetivo es realizar una revisiónbibliográfica enfocada en las diversas comprensiones, conceptualizaciones, descripciones ysimbolismos que compusieron y generaron un imaginario compartido sobre el origen de estaentidad territorial entre los siglos xvi y xx. A partir de las cuestiones levantadas a lo largo deltexto, son señaladas ciertas características de la relación entre la producción científica y las narraciones generadas en su proceso histórico. El artículo se orienta de forma cronológica y sedivide en seis partes: 1) las concepciones pre-científicas de la amazonia; 2) el surgimiento de lasgrandes teorías científicas del siglo xix; 3) la institucionalización de la arqueología amazónica;4) la elaboración de los modelos arqueológicos; 5) las implicaciones culturales y políticas de lanarración arqueológica; y 6) consideraciones finales.
Buenos Aires Camina. Violencia, Capitalismo y Segregación (1976-1982)
Authors: Inclán Daniel
Published: January 2025

Este artículo presenta una genealogía del autoritarismo dictatorial a través del estudio del proyecto urbano de la ciudad de Buenos Aires, bajo el gobierno de Osvaldo Cacciatore.El trabajo hace un cruce entre el proyecto urbano, las transformaciones arquitectónicas y losdiscursos contrainsurgentes, para exponer la relación entre violencia, capitalismo y segregación.El objetivo es pensar la producción del espacio que está detrás de la violencia castrense.
Features of Family Upbringing of Adolescents with Different Levels of School Anxiety
Authors: Muslumov Rustam R. , Pecherkina Anna A. , Symanyuk Elvira E.
Published: January 2025

The article presents the results of research into the relationship between the characteristics of family upbringing and indicators of school anxiety in adolescents aged 11–15 years. It has been established that there is a significant relationship between violations of the parenting style and the level of school anxiety. Among the features of family education of adolescents demonstrating a high level of school anxiety are: overprotection, excessive requirements and prohibitions, instability of the parenting style. The role of emotional support of the family in the formation of a positive emotional state of adolescents and the ability to cope with academic stress is characterized.
The obtained results can be used when working with adolescents, as well as for developing programs for their psychological support and programs to support parents and inform them of possible parenting styles and their impact on the emotional state and academic progress of children.
The Role of Family in the Therapy of Nervous Anorexia
Authors: Kostyuk Georgy P. , Mazurova Yevgenia V. , Karpenko Olga A. , Severtsev Vsevolod V. , Gurova Kristina A. , Chernov Nikita V.
Published: January 2025

The aim of the study was to assess the relationship between the level of involvement of the family of patients with anorexia nervosa in therapeutic measures during routine treatment in the EDC and patients’ compliance to treatment. We analyzed 104 cases of patients with anorexia nervosa who were treated at the EDC during 2022–2023 at the full-time division, the half-time division and the dispensary division. It was found that among patients whose relatives did not attend psychoeducation events, 66.7% (n=10) did not continue treatment after discharge from the full-time division, patients whose relatives attended events partially and completely did not continue treatment in 15.4% (n=2) and 24.3% (n=18) cases, respectively. It was found that patients whose families did not participate in psychoeducation activities spent significantly less time in a full-time division (17 days). In the case of partial and full family involvement, patients stayed in the hospital for an average of 51 days and 54 days, respectively. Thus, it was found that family involvement is an important compliance factor at all stages of treatment.
Young People’s Attitude Towards Family and Marriage
Authors: Rean Artur A. , Konovalov Ivan A.
Published: January 2025

The article discusses the results of a study on social representations among young people regarding attitudes towards family and marriage, individual prospects, plans for family creation, unregistered marriages, and childbirth in these unions. It also explores attitudes towards the reasons for starting a family and conditions for a successful marriage, as well as changes in social representations over time. The study analyzes trends in the general attitudes of young people towards these topics over a period of six years. It finds that most respondents believe it is necessary to prepare individuals for starting a family by teaching family values, and there is an increasing trend towards introducing courses on family life in schools. The vast majority of young people plan to start a family and have two children in the future. However, there is also a growing trend among young people to plan for having only one child. The results of this study are discussed in light of demographic trends and current issues in youth policy.
PENGARUH RASIO KEUANGAN TERHADAP FINANCIAL DISTRESS DENGAN PENDEKATAN SPRINGATE (S-SCORE)
Authors: Ayundasari Vina , Kurniawati Eris Tri
Published: January 2025

Prediction analysis results financial distress can be used to minimize losses for internal or external parties as a result of bankruptcy experienced by the company, as well as predicting the continued existence of the company concerned. The aim of this research is to analyze the influence of liquidity ratios, profitability ratios, non-performing credit ratios and effectiveness ratios on financial distress. The population in this research is Sharia People's Financing Banks (BPRS) in East Java which are registered with the Financial Services Authority in 2018-2022. The data analysis method for this research uses panel data regression analysis. Based on research results regarding the influence of liquidity ratios, profitability ratios, non-performing credit ratios and effectiveness ratios on financial distress at BPRS in East Java. The liquidity ratio has a positive and insignificant effect on financial distress. The profitability ratio has a positive and significant effect on financial distress. The non-performing loan ratio has a negative and insignificant effect on financial distress. The effectiveness ratio has a negative and significant effect on financial distress.
Climate change is (NOT) funny: insights from a climate change comedy event
Authors: Riley James , Hall Alexander
Published: January 2025

In recent years there has been an increasing call for new modes of climate change communication. These calls have gone beyond classic consensus-building and fact-sharing to addressing affective dimensions and meaning-making in relation to the climate crisis. In this article we reflect on a proof-of-concept climate change comedy project — “Climate Change is NOT Funny!”. Building on audience and performer insights, we reflect on the effectiveness and affective dimensions of comedy as a climate change communication method, as well as institutional and funding constraints on delivery. Finally, we introduce how we designed our project to go on making an impact beyond the grant's lifespan. By empowering professional comedians to embed new research-informed climate change material into their regular sets, we argue that our approach can amplify the reach of climate communication activities, and in turn provide new forums for individuals to engage with the most pressing aspects of the climate crisis.
Out-of-time-ordered correlators of mean-field bosons via Bogoliubov theory
Authors: Lemm Marius , Rademacher Simone
Published: January 2025

Quantum many-body chaos concerns the scrambling of quantum information among large numbers of degrees of freedom. It rests on the prediction that out-of-time-ordered correlators (OTOCs) of the form ⟨[A(t),B]2⟩ can be connected to classical symplectic dynamics. We rigorously prove a variant of this correspondence principle for mean-field bosons. We show that the N→∞ limit of the OTOC ⟨[A(t),B]2⟩ is explicitly given by a suitable symplectic Bogoliubov dynamics. In practical terms, we describe the dynamical build-up of many-body entanglement between a particle and the whole system by an explicit nonlinear PDE on L2(R3)⊕L2(R3). For higher-order correlators, we obtain an out-of-time-ordered analog of the Wick rule. The proof uses Bogoliubov theory. Our finding spotlights a new problem in nonlinear dispersive PDE with implications for quantum many-body chaos.
Prediction of Postpartum Depression With Dataset Using Hybrid Data Mining Classification Technique
Authors: Arya P. Pillai  , N.V. Chinnasamy
Published: January 2025

Postpartum Depression is a condition or a state which usually affects the woman immediately after child birth. The birth of a baby not only brings delighted emotions such as excitement, but also fear and anxiety which may sometimes lead to depression. It is a period of physical, emotional and behavioral changes that happen in some woman immediately after the delivery. Apart from the chemical changes, there are many factors which affect a woman during and after pregnancy period. If PPD is not identified and treated at the earlier stages, it may lead to serious issues for mother and child. It is therefore of vital importance to sift through the woman at any early stage to prevent any consequences. The objective of this study is to find out the presence of PPD without getting worse. Data mining plays an important role in the health care industry with successful outcome. It helps to find out hidden patterns, trends and anomalies from large dataset to make the predictions. The proposed system is a combined classification technique for the prediction of postpartum depression that uses Support vector machine, Artificial Neural Network and Hybrid classifier algorithm to produce the best result.
Advanced shooting target with bullet collector, semi-automatic bulls-eye paper positioning and automatic shooting score
Authors: Hendriana Dena , Umniyati Yunita , Soonggalon Erikson Ferry , Averino Isaac Hansen , Gartina Mohammad Rizky , Aryo Rakhmad , Iwan Iwan , Yahya Prima Kharisma Indra
Published: January 2025

Shooting exercises in Indonesia typically use simple bulls-eye targets on wooden boards with sand backstops, requiring manual setup and score calculation. This setup is inefficient, especially for long-range shooting, as operators must walk far to retrieve targets, and bullets embedded in sand are hard to recycle. This project developed an advanced shooting target featuring a bullet collector, semi-automatic target setup, automatic scoring, and target monitoring. A system with such complete features is not available in the market. This target system has a roll of bulls-eye paper and the roller is powered by a servo motor controlled by a switch to command a fresh new page of bulls-eye its positioning is helped by an infrared sensor to detect markers in the paper for correct positioning. This system is equipped with a bullet collector system by directing the bullet to a container using 450 angled armor and a layer of sand in the container to stop the bullet. This system is also equipped with a camera pointing to the bulls-eye paper and its output is transmitted to a monitor close to the shooter to identify bullet tracks for evaluating his shooting performance and to improve his shooting strategy. The image from the same camera is used for image processing with the OpenCV library and Python scripts to calculate the shooting score automatically. Several physical tests have been conducted and the system proves to perform reasonably well in the tests with some errors of around 3% for single bullet holes and simple multiple bullet holes. Based on test results, the pistol bullets have quite different properties from the rifle bullets. Pistol bullets follow the impact deflection with a coefficient of restitution e = 0 while rifle bullets follow the impact deflection with e ≈ 0.5. The pistol bullets are completely disintegrated after impact while the rifle bullets are just distorted.
Understanding passenger satisfaction and expectations in free bus service based on socio-demographic characteristics in Johor and the Klang Valley, Malaysia
Authors: Zakaria Husna , Md. Rohani Munzilah , Mohd Pozi Muhammad Fazreen
Published: January 2025

Free bus service is known to serve passengers with the same goal as normal bus does. In fact, the implementation of free bus service acts as an alternative solution for those who have financial limitations. To keep a high satisfaction level of passengers regardless of various backgrounds, it is important for the free bus providers to maintain the quality of their service. Therefore, this study aims to understand the relationship between socio-demographic characteristics and the satisfaction level and expectation of passengers on free bus services allocated in Klang Valley and Johor, Malaysia. A survey was conducted among the free bus users to collect data on their socio-demographic characteristics and their experiences with the service quality offered. According to the survey, teens and single people were the primary passengers of the free bus service. Moreover, passengers who had low income, no driving license, and no vehicles were also more likely to use the service. The overall satisfaction level of passengers was high (mean score > 3.6), indicating that the service quality provided by the free bus service provider met the expectations of passengers. However, no evidence was found from this study to relate socio-demographic factors with satisfaction level.