bluuebunny/crossref_metadata_2025 huggingface dataset:
Vitamin D Target Genes in Dental Health
Authors: Shivakumar Ashwini Tumkur , Kalgeri Sowmya Halasabalu , Santhekadur Prasanna K.
Published: September 2022

INTRODUCTION: Vitamin D is an important molecule which plays pivotal role in overall human health and metabolism. This vitamin acts as both vitamin as well as hormone, and thus, dual nature of this vitamin makes it as one of the important chemicals required for the overall health, harmonious growth, and development. Recently, this vitamin is gaining large attention in dentistry, and it is becoming master regulator of dental health. It is well studied that vitamin D plays major role in calcium absorption for bone and teeth mineralisation, it acts as odontogenic inducer of differentiation of human dental pulp cells and in tooth development.

STUDY SELECTION, DATA, AND SOURCES: Vitamin D regulates various signalling pathways in dental network and plays a beneficial role. Synthesis of vitamin D takes place in multiple steps in human body. The natural form of vitamin D is fat soluble in nature and is produced in the skin from 7-dehydrocholesterol molecules. Natural Sunlight through its ultraviolet B (UVB) energy converts the precursor7-dehydrocholesterol molecules to vitamin D3. Advanced and unhealthy lifestyle of modern times has led to the deficiency of vitamin D and metabolic syndrome.

CONCLUSIONS: Deficiency of vitamin D also leads to various dental problems including dental caries, gingivitis, and periodontal disease. In this short review, we are discussing the role of vitamin D and importance of its target genes in dental health.

CLINICAL RELEVANCE: Vitamin D has a major role in managing the oral health this article updates the clinician with the different genes which are responsible for the regulation of vitamin D in different tissues.
Impact of low energy electron beam on black pepper (Piper nigrum L.) microbial reduction, quality parameters, and antioxidant activity
Authors: Gaba Abdul Basit M. , Hassan Mohamed A. , El-Tawab Ashraf A. Abd , Abdelmonem Mohamed A. , Morsy Mohamed K.
Published: September 2022

Low energy electron beam (e-beam) has the ability to decontaminate or reduce bioburden and enhance the food product's safety with minimal quality loss. The current study aimed to evaluate the efficacy of e-beam on natural microbiota and quality changes in black peppercorns. The black pepper was exposed to e-beam at doses from 6–18 kGy. The microbial quality, physicochemical attributes, total phenolic compounds, and antioxidant activity were evaluated. Results demonstrated the microbial population in black pepper decreased with increasing e-beam treatment doses. Significant inactivation of Total Plate Count (TPC), yeasts, and molds were observed at dose 6 kGy by 2.3, 0.7, and 1.3 log CFU g−1, respectively, while at 18 kGy the reduction level was 6, 2.9, and 4.4 log CFU g−1, respectively. Similarly, 18 kGy of e-beam yielded a reduction of 3.3 and 3.1 log CFU g−1 of Salmonella Typhimurium and coliform bacteria, respectively. A significant difference (p < 0.05) was noted between doses 12, 15, and 18 kGy on Bacillus cereus and Clostridium perfringens in black pepper. During e-beam doses, the values L*, a* and b* of black peppercorn were not noticeably altered up to 18 kGy dose. No significant (p > 0.05) difference in moisture, volatile oil, and piperine content upon (6–18 kGy) treatments in comparison to the control. A slight difference in the bioactive compound, retaining > 90% of total phenolic compounds and antioxidant activity. Results revealed that e-beam doses ≥ 18 kGy were influential for inactivating natural microbes and foodborne pathogens without compromising the physicochemical properties and antioxidant activity of black peppercorns.
A reduced distribution of the modified Weibull distribution and its applications to medical and engineering data
Authors: Ghazal M. G. M. , Radwan H. M. M.
Published: September 2022

In this work, we suggest a reduced distribution with two parameters of the modified Weibull distribution to avoid some estimation difficulties. The hazard rate function of the reduced distribution exhibits decreasing, increasing or bathtub shape. The suggested reduced distribution can be applied to many problems of modelling lifetime data. Some statistical properties of the proposed distribution have been discussed. The maximum likelihood is employed to estimate the model parameters. The Fisher information matrix is derived and then applied to construct confidence intervals for parameters. A simulation is conducted to illustrate the performance of maximum likelihood estimation. Four sets of real data are tested to prove the proposed distribution advantages. According to the statistical criteria, the proposed distribution fits the tested data better than some well-known two-and three-parameter distributions.
Chemical composition and thermal properties of Tunisian pecan nut [Carya illinoinensis (Wangenh.) K. Koch] oils
Authors: Bouali I. , Rattouli H. , Herchi W. , Martine L. , Grégoire S. , Albouchi A. , Martínez-Force E. , Boukhchina S. , Berdeaux O.
Published: September 2022

An investigation on fatty acid, triacylglycerol, tocopherol, and xanthophyll contents and thermal properties of pecan (Carya illinoinensis) kernel oils from two cultivars was carried out. The main fatty acids were oleic acid, followed by linoleic and palmitic acids. The predominant triacylglycerols were OOL, OOO, and OLL (where O stands for oleoyl and L for linoleoyl). Pecan kernel oil is a rich source of tocopherols, mainly γ-tocopherol. Two xanthophylls (lutein and zeaxanthin) were investigated, and lutein was found to be the major one. Thermal behavior was studied by differential scanning calorimetry (DSC). Pecan nut oil displayed melting and crystallization transitions at low-temperature zones. The difference between DSC parameter values provides a path for distinguishing among cultivars. These data promote pecan kernel oil as a potential source of bioactive compounds with nutraceutical properties (monounsaturated fatty acids, tocopherols, and xanthophylls) and reveal, for the first time, the thermal properties of Carya illinoinensis oil.
Effects of Blended, Explicit and Implicit Instruction on EFL Learners in English Pronunciation Class under Emerging Technology
Authors: Luo Zhilin , Shao Xuefeng , Wareewanich Thitinant
Published: September 2022

As the most important foreign language in China, English poses great challenge for teachers to improve the performance of ESL (English as a second language) learners through in-class instruction. Blended, explicit, and implicit instruction are three widely used approaches in English class teaching, and it may be difficult to choose which one should be used in class to help the English language learners. With audio synthesis technology applied as an enhancement for teaching, this study aims to research the three effects on English pronunciation teaching in aspects of the performance and satisfaction of English language learners. 120 English learners in China were equally divided into three groups which were instructed by blended, explicit, and implicit instruction respectively. Based on the data collected by test and questionnaire in pre-test, in-test, and post-test, the results show that the blended instruction performs best in aspects of the improvement of performance and the class satisfaction. These findings indicate the great potential of blended instruction in English language teaching and more investment should be taken to promote its application to help the Chinese to better acquire this important language.
How do artist-entrepreneurs exercise their creative freedom with respect to the mechanisms governing them? The case of the performing arts
Authors: Burkhardt-Bourgeois Kirsten , Jarrier Elodie , Bourgeon-Renault Dominique
Published: September 2022

This article analyses the resources artist-entrepreneurs have to hand to protect their creative freedom and so lessen their dependence with respect to the mechanisms that govern them. It relies on a study of multiple cases in the performing arts. The results of a manual content analysis of semi-directed interviews with five theatrical companies in Bourgogne Franche-Comté (France) highlight the importance of networks and informal mechanisms, like trust and reputation, as well as the building of long-term relationships with stakeholders. Formal governance mechanisms, such as boards of directors, play very variable roles.
A Pandemic World
Authors: Teichert Laura
Published: September 2022

This chapter reports on an autoethnographic study of one mother-child dyad's experience navigating the child's transition into online kindergarten in midwestern USA during the COVID-19 pandemic. The inquiry examined how the dual role of mother and teacher affected interactions between mother and son. Key findings focused on the struggle of the mother as teacher through the persistence of the grammar of schooling. The mother reported strong feelings of guilt as she sought to adhere to the school's expectations even when those expectations clashed with the regular routine and practices of the home. Additionally, there was a sense of school community loss; however, the mother reported an increase in parent-teacher communication and the feeling of access to her son's classroom learning.
Masked Transient Effect Ring Oscillator Physical Unclonable Function Against Machine Learning Attacks
Authors: Narasimhan Sivasankari
Published: September 2022

Many types of physical unclonable function (PUF) structures have been proposed in the last decade. The responses generated from the conventional PUF are vulnerable to attack. In this chapter, the transient effect of ring oscillator structure has been used. This works on two loops with complex loops containing NOT gates and NAND gates. Response prediction of these loops is a very difficult task for the adversary. Many machine learning algorithms may produce the responses with higher accuracies. This study provides new masked PUF architectures that are more secure and invulnerable to modeling attacks. Hence, in this chapter, masking-based configurability design on various PUF structures is introduced. This will be helpful for resource-constrained machines. For different sizes of challenge-response pair, machine learning techniques need to be changed, but prediction accuracy by the attacker should be low. By using this kind of masked PUF structure, 54.7% uniqueness can be obtained, and 97.5% reliability can be achieved. Machine learning accuracy is 70.7% with SVM and 63.67% accuracy in LR.
A Stock Trading Expert System Established by the CNN-GA-Based Collaborative System
Authors: Wu Jimmy Ming-Tai , Sun Lingyun , Srivastava Gautam , Diaz Vicente Garcia , Lin Jerry Chun-Wei
Published: September 2022

This article uses a new convolutional neural network framework, which has good performance for time series feature extraction and stock price prediction. This method is called the stock sequence array convolutional neural network, or SSACNN for short. SSACNN collects data on leading indicators including historical prices and their futures and options, and uses arrays as the input map of the CNN framework. In the financial market, every number has its logic behind it. Leading indicators such as futures and options can reflect changes in many markets, such as the industry's prosperity. Adding the data set of leading indicators can predict the trend of stock prices well. This study takes the stock markets of the United States and Taiwan as the research objects and uses historical data, futures, and options as data sets to predict the stock prices of these two markets, and then uses genetic algorithms to find trading signals, so as to get a stock trading system. The experimental results show that the stock trading system proposed in this research can help investors obtain certain returns.
Desórdenes musculoesqueléticos, estrés y calidad de vida en docentes de un centro del Servicio Nacional de Aprendizaje
Authors: Montoya Grisales Noelva Eliana , González Palacio Enoc Valentín
Published: September 2022

Objetivo. Esta investigación se propuso establecer la relación entre los desórdenes musculoesqueléticos, el estrés y la calidad de vida de los docentes de un centro del Servicio Nacional de Aprendizaje. Materiales y Método. El estudio fue cuantitativo, no experimental, descriptivo. La muestra estuvo constituida por 55 docentes, seleccionados de forma probabilística aleatoria simple. Los instrumentos utilizados fueron el cuestionario nórdico de desórdenes musculoesqueléticos, el cuestionario de estrés del Ministerio de la Salud y de la Protección Social y el test de calidad de vida WhoQol Bref – versión en español, autorizada por la Organización Mundial de la Salud. El análisis de datos se realizó en el software SPSS versión 23, a partir de estadísticos descriptivos (mediana y rango intercuartílico) y correlativos (r Pearson y Rho Spearman), teniendo en cuenta la distribución normal, la cual se calculó a partir de la prueba Kolmogorov Smirnov. Resultados. Se encontró relación positiva y asociación estadísticamente significativa entre los desórdenes musculoesqueléticos y los síntomas de estrés y el estrés general (p<0,5 y p<0,01). También se encontró correlación negativa y asociación estadística entre los desórdenes musculoesqueléticos y la mayoría de dominios de la calidad de vida y resultados similares al relacionar el estrés con la calidad de vida (p<0,5 y p<0,01). Conclusión. Se encontró que a mayor presencia de desórdenes musculoesqueléticos y estrés, menor es la calidad de vida en los docentes participantes del estudio.
Unlocking Early-Stage Financing for SDG Partnerships
Authors: Li Serena , Gray Erin , Dennis Maggie , Hand Dean , Avi Shrikant
Published: September 2022

Mobilizing finance and multistakeholder partnerships are key priorities for the global community to accelerate the SDGs. Yet, many partnerships are not able to reach their ambitions because they cannot access early-stage financing. This report aims to help partnerships and their funders effectively manage and mobilize finance to achieve SDG impact by: exploring partnership funding challenges and lessons learned; examining innovative funding approaches; and providing tangible recommendations to partnerships and funders on how to drive SDG impact more effectively.
Systemic lupus erythematosus: history and modernity
Authors: Nasonov E. L. , Soloviev S. K. , Arshinov A. V.
Published: September 2022

Systemic lupus erythematosus (SLE) is a systemic autoimmune rheumatic disease of unknown etiology, characterized by hyperproduction of non-organ-specific autoantibodies to various components of the cell nucleus and the development of immune-inflammatory damage to internal organs. Currently, SLE is considered as a prototype of a systemic human autoimmune pathology, the central mechanism of immunopathogenesis of which is a violation of immunological tolerance to self-antigens, due to a complex interaction of genetic, epigenetic, environmental factors. The publication discusses the history of the study of SLE, the contribution of Russian scientists (V.A. Nasonova and others) to the study of th is problem, current trends in clinical and scientific research related to the improvement of diagnostic criteria and pharmacotherapy of this disease.
Predisposing role of childhood mental trauma in immunoinflammatory rheumatic diseases and mental disorders
Authors: Alekseeva S. A.
Published: September 2022

Psychic trauma received in childhood is a common phenomenon that causes damage to the child’s body that hasn’t been fully formed. Severe traumatic events in childhood disrupt the development of regulatory systems, which can lead to the occurrence of many diseases and disorders: increased risk of developing mental disorders, rheumatic, cardiovascular and oncological diseases, and reduced life expectancy. This article discusses the pathogenetic aspects of the influence of psychotraumas experienced in childhood on the occurrence of systemic inflammation and, as a result, the development of mental disorders and rheumatic diseases in adults.
PELATIHAN TRIK CARA CEPAT MENJAWAB SOAL SBMPTN
Authors: Simamora Yumira , Matondang Khoiruddin , Bella Risna Mira , Siswadi Siswadi
Published: September 2022

Ujian Tulis Berbasis Komputer (UTBK) wajib diikuti bagi siswa yang ingin ingin masuk ke perguruan tinggi negeri dengan jalur SBMPTN. Tujuan kegiatan ini adalah memberikan pemahaman kepada siswa kelas XII trik cara cepat menjawab soal UTBK jalur SBMPTN. Sedangkan tujuan tujuan UTBK adalah memprediksi calon mahasiswa dalam menyelesaikan kuliah di kampus yang dipihnya dengan baik dan tepat waktu. Dengan demikian siswa kelas XII penting dan perlu mempersiapkan diri dan mengetahui trik atau cara cepat menyelesaikan soal UTBK matematika. Kegiatan pengabdian ini dilaksanakan di Madrasah Aliyah Laboratorium IAIN Medan pada tanggal 18 November 2021. Sasaran dari kegiatan ini adalah siswa kelas XII dan XII   MIPA A dan B sejumlah 69 siswa. Materi yang disampaikan adalah Limit Fungsi ALjabar dan Perbandingan. Berdasarkan hasil evaluasi, target utama dari pelaksanaan kegiatan ini telah tercapai. Siswa mengetahui cara trik atau cara cepat, 81% siswa mampu mengerjakan soal Limit fungsi Aljabar, dan Perbandingan dengan cepat, benar dan baik.
The role of current herbal extracts in bone regeneration through dental implants: in vitro/ in vivo/ clinical studies
Authors: Eftekhar Ashtiani Reza , Hadi Alireza , Nouri Farzad , Rahimi Saeide , Badkoobeh Ashkan , Abbasi Kamyar , Alam Mostafa
Published: September 2022

The quality and quantity of bone at the interface of an implant system is a determining factor in the implant's stability. Alternative agents have been studied to augment implants and bone defects, including bone-conductive and bone-inducing agents. By modifying implant surface coatings on the nanoscale, one can enhance osseointegration by stimulating bone cell adhesion, bone matrix formation, and mineralization. Because alternative agents stimulate osteoblasts to mineralize and can control pectin structure, plant-derived silicone has been suggested as a potential candidate for surface nanocoatings on orthopedic and dental titanium implants. Inducing the differentiation of cells or accelerating bone regeneration is possible with the plant extract. Coating these extracts on implant devices can improve cell attachment, differentiation, and proliferation. This review article discusses the role of herbal materials in bone regeneration through dental implants.
KARAKTER PENYIAR KREATIF DALAM SIARAN BERITA DI RADIO SEILA 104.3FM BATAM
Authors: Aminudin Angga , Nurani Muksin Nani
Published: September 2022

Sebagai media penyedia informasi, setiap radio memiliki konsep masing-masing dalam menjalankan format siarannya. Seperti di Indonesia, terdapat banyak radio yang format siarannya beragam dengan multi segmen pendengar. Radio Seila FM Batam ini memiliki format siaran umum, dalam arti menggabungkan hiburan, berita dan musik dalam satu format siaran bernuansa religi Islam. Ternyata dalam beberapa tahun, program acara yang paling banyak diminati oleh pendengarnya adalah acara “Topik Berita Pagi”. Penyiar acara “Topik Berita Pagi” ini memiliki peranan yang cukup signifikan dalam proses pengembangan dan penyampaian informasi kepada pendengar. Karakter yang dibangun dan dipersiapkan oleh penyiarnya agar bisa menarik pendengar dilakukan dengan professional dan kreatif. Penelitian ini bertujuan untuk mengetahui kreatifitas penyiar acara “Topik Berita Pagi”. Dengan metode kualitatif yang digunakan adalah fenomenologi deskriptif yang didasarkan pada filosopi Husserl. Fenomenoligi deskriptif ini digunakan untuk mengembangkan struktur pengalaman hidup penyiar yang berkolaborasi dengan tim program acara berita yang bertanggung jawab menyiapkan semua konten siaran berita dengan durasi sekitar 90 menit. Bisa dilihat karakter penyiar kreatif yang paling menonjol dari program ini adalah; Mempunyai kualitas vokal yang memadai, handal dalam melaksanakan ‘adlibbing’ dan ‘script reading’, up-to date dan memiliki wawasan yang luas, memahami secara mendalam segmen radio, memperlihatkan simpati dan empati terhadap pendengarnya, Mampu menghasilkan gagasan-gagasan segar dan solutif, Mampu bekerjasama dalam tim dan “Be Your Self”. Di sebuah stasiun radio, penyiar kreatif membawakan sebuah acara tentunya memiliki nilai strategis. Karena berita-berita terkini yang dikemas dengan sedemikian rupa, disampaikan kepada pendengarnya dengan sangat baik dan menarik sehingga menimbulkan respon yang positif dari pendengar. Hal ini akan berguna dalam upaya radio mempertahankan eksistensinya di dunia penyiaran.
Excess radiation exacerbates drought stress impacts on canopy conductance along aridity gradients
Authors: Wang Jing , Wen Xuefa
Published: September 2022

Abstract. Stomatal conductance (gs) of all coexisting species
regulates transpiration in arid and semiarid grasslands prone to droughts.
However, the effect of drought stress on canopy conductance (Gs) is
debated, and the interactive effects of abiotic and biotic constraints on
Gs remain poorly understood. Here, we used 18O enrichment above the
source water (Δ18O) of leaf organic matter as a proxy for Gs in order to
increase the understanding of these effects. Three grassland transects were
established along aridity gradients on the Loess Plateau (LP), the Inner Mongolian
Plateau (MP), and the Tibetan Plateau (TP), which differ with respect to solar radiation and
temperature conditions. Results showed that Gs consistently decreased
with increasing aridity within transects. Gs on the TP was lower than that
on the other two plateaus for a given level of aridity due to low
temperature and high radiation. The primary determinant of drought stress on
Gs was soil moisture (SM) on the LP and MP, whereas it was the vapor pressure deficit
(VPD) on the TP. Solar radiation exhibited a consistently negative effect on
Gs via drought stress within transects, while temperature had negative
effects on Gs on the TP but no effect on the LP or MP. Adding the
interaction of leaf area and abiotic factors increases the percentage of
explained variability in Gs by 17 % and 36 % on the LP and MP,
respectively, although this is not the case on the TP, where the climate exerts an overwhelming effect.
These results highlight the need to integrate multiple stressors and plant
properties to determine spatial variability in Gs.
Past and future response of the North Atlantic warming hole to anthropogenic forcings
Authors: Qasmi Saïd
Published: September 2022

Abstract. Most of the North Atlantic ocean has warmed over the last decades, except a region located over the subpolar gyre, known as the North Atlantic warming hole, where sea surface temperature has in contrast decreased. Previous assessments have attributed part of this cooling to the anthropogenic forcings (aerosols and greenhouse gases) modulated by decadal internal variability. Here I use an innovative and proven statistical method which combines climate models and observations to confirm the anthropogenic role in the WH cooling, and to provide estimates of the contribution of a set of given external forcings. Furthermore, the method is able to reduce the uncertainty in the WH temperature over the historical period, but also in the future, with a decrease of 65 % in the short term, up to 50 % in the long term. A model evaluation validates the reliability of the obtained projections. In particular, the projections associated with a strong temperature increase over the warming hole are now excluded from the likely range obtained after applying the method.
Quantifying stocks in exchangeable base cations in permafrost: a reserve of nutrients about to thaw
Authors: Mauclet Elisabeth , Villani Maëlle , Monhonval Arthur , Hirst Catherine , Schuur Edward A. G. , Opfergelt Sophie
Published: September 2022

Abstract. Permafrost ecosystems are limited in nutrients for vegetation development and constrain the biological activity to the active layer. Upon Arctic warming, permafrost degradation exposes large amounts of soil organic carbon (SOC) to decomposition and minerals to weathering, but also releases organic and mineral soil material that may directly influence the soil exchange properties (cation exchange capacity and base saturation). The soil exchange properties are key for nutrient base cation supply (Ca2+, K+, Mg2+) for vegetation growth and development. In this study, we investigate the distribution of soil exchange properties within typical Arctic tundra permafrost soils at Eight Mile Lake (Interior Alaska, USA) because they will dictate the potential reservoir of newly thawed nutrients and thereby influence soil biological activity and vegetation nutrient sources. Our results highlight a difference in the SOC distribution within soil profiles according to the permafrost thaw. The poorly thawed permafrost soils (active layer thickness; ALT ≤ 60 cm) present more organic material in surface (i.e., organic layer thickness; OLT ≥ 40 cm) than the highly thawed permafrost soil (i.e., ALT > 60 cm and OLT < 40 cm). In turn, this difference in SOC distribution directly affects the soil exchange complex properties. However, the low bulk density of organic-rich soil layers leads to much lower CEC density in surface (~9 400 cmolc m-3) than in the mineral horizons of the active layer (~16 000 cmolc m-3) and in permafrost soil horizons (~12 000 cmolc m-3). As a result of the overall increase in CEC density with depth and the overall increase in base saturation with depth (from ~20 % in organic surface to 65 % in permafrost soil horizons), the average total stock in exchangeable base cations (Ca2+, K+, Mg2+ and Na+ in g m-3) is more than 2-times higher in the permafrost than in the active layer. More specifically, the stocks in base cations in the upper part of permafrost about to thaw in the following are ~ 860 g m-3 for Caexch, 45 g m-3 for Kexch, 200 g m-3 for Mgexch and 150 g m-3 for Naexch. This first order estimate is a needed step for future ecosystem prediction models to provide constraint on the size of the reservoir in exchangeable nutrients (Ca, K, Mg) about to thaw.
Reconstruction of past exposure to natural hazards driven by historical statistics: HANZE v2.0
Authors: Paprotny Dominik , Mengel Matthias
Published: September 2022

Abstract. Understanding and quantifying the influence of climate change on past extreme weather impacts is vital for climate litigation, the loss and damage debate, and for building more accurate models to assess future impacts. However, the effects of climate change are obscured in the observed impact data series due to the rapid evolution of the social and economic circumstances in which the extreme events occurred. The model and data presented in this study (HANZE v2.0) aims at quantifying the evolution of key socioeconomic drivers in Europe since 1870, namely land use, population, economic activity and assets. It consists of algorithms to reallocate baseline (2011) land use and population for any given year based on a large collection of historical subnational- and national-level statistics, and then disaggregate data on production and tangible assets by economic sector into a high-resolution grid. Maps generated by the model enable reconstructing exposure within the footprint of any extreme event both at the time of the event and in any other moment in the past 150 years. This allows the separation of the effects of climate change from the effects of exposure change. In addition, HANZE v2.0 can be used for assessing socio-economic influences on hazard (e.g. effects of land use-change on hydrological extremes) and vulnerability (e.g. the changing structure of assets at risk).
Inertia and seasonal climate prediction as sources of skill in lake temperature, discharge and ice-off forecasting tools
Authors: Clayer François , Jackson-Blake Leah , Mercado Daniel , Shikhani Muhammed , French Andrew , Moore Tadhg , Sample James , Norling Magnus , Frías Maria-Dolores , Herrera Sixto , de Eyto Elvira , Jennings Eleanor , Rinke Karsten , van der Linden Leon , Marcé Rafael
Published: September 2022

Abstract. Despite high potential benefits, the development of seasonal forecasting tools in the water sector has been slower than in other sectors. Here we assess the skill of seasonal forecasting tools for lake and reservoir set up at four sites in Australia and Europe. These tools, as previously presented, consist of coupled hydrological catchment and lake models forced with seasonal climate forecast ensembles to provide probabilistic predictions of seasonal anomalies in water discharge, temperature and ice-off. Successful implementation requires a rigorous assessment of the tools’ predictive skill and an apportionment of the predictability between legacy effects and input data. To this end, models were forced with two meteorological datasets from the European Centre for Medium Range Weather Forecasts (ECMWF), the seasonal forecasts SEAS5 and the ERA5 reanalysis. Historical skill was assessed by comparing both model outputs, i.e., seasonal lake hindcasts (forced with SEAS5) and pseudo-observations (forced with ERA5). The skill of the seasonal lake hindcasts was generally low, but higher than SEAS5 climate hindcasts. Nevertheless, lake and SEAS5 windows of opportunity were identified, although they were not always synchronous, raising questions on the source of the predictability. A set of sensitivity analyses showed that most of the forecasting skill originates from legacy effects, although during winter and spring in Norway some skill was coming from SEAS5 over the target season. When SEAS5 hindcasts were skillful, additional predictability originates from the interaction between legacy and SEAS5 skill. We conclude that a climatology driven forecast is currently likely to yield higher quality forecasts.
Brief communication: Everest South Col Glacier did not thin during the last three decades
Authors: Brun Fanny , King Owen , Réveillet Marion , Amory Charles , Planchot Anton , Berthier Etienne , Dehecq Amaury , Bolch Tobias , Fourteau Kévin , Brondex Julien , Dumont Marie , Mayer Christoph , Wagnon Patrick
Published: September 2022

Abstract. The South Col Glacier is an iconic small body of ice and snow (approx. 0.2 km2), located on the southern ridge of Mt. Everest. A recent study proposed that South Col Glacier is rapidly losing mass. This seems in contradiction with our comparison of two digital elevation models derived from aerial photographs taken in 1984 and a stereo Pléiades satellite acquisition from 2017, from which we measure a mean elevation change of 0.01 ± 0.07 m a-1. To reconcile these results we investigate wind erosion and surface energy and mass balance, and find that melt is unlikely a dominant process, contrary to previous findings.
Nominative Linkage of Records of Officials in the China Government Employee Dataset-Qing (CGED-Q)
Authors: Campbell Cameron , Chen Bijia
Published: September 2022

We introduce our approach to the nominative linkage of records of Qing officials who were included in the China Government Employee Datasets-Qing (CGED-Q) Jinshenlu (JSL) and Examination Records (ER). We constructed these datasets by transcription of quarterly rosters of civil and military officials produced by the government and by commercial presses, and records of examination degree holders. We assess each of the primary attributes available in the original sources in terms of their usefulness for disambiguation, focusing on their diversity and potential for inconsistent recording. For officials who were not affiliated with the Eight Banners, these primary attributes include surname, given name, and province and county of origin. For the small subset of officials who were affiliated with the Bannermen, we assess the available data separately. We also assess secondary attributes available in the data that may be useful for adjudicating candidate matches. We then describe the approach that we developed that addresses the issues we identified with the primary and secondary attributes. The issues we have identified and the approach that we have developed will be of interest to researchers engaged in similar efforts to construct and link datasets based on elite males in historical China.
Urgensi Maqashid Syariah Dalam Pengembangan Ekonomi
Authors: Darma Satria
Published: September 2022

This study aims to analyze the urgency of Islamic maqashid in economic development. This research uses exploratory study method, descriptive analysis in analyzing secondary data related to these problems. The results show that maqashid on the Theory of Economic Behavior can be seen in: Economic Problems, Wants versus Needs, and Mashlahah versus Utility.
A Brief Review on Pharmaceutical Validation
Authors: A. Salade Darshan , S. Arote Kishor , Patil P. H. , V. Patil Vikas , R. Pawar Amol
Published: September 2022

Validation is the procedure which authorizing documentary evidence that proves the following process will consistently produce the product which leads to the expected result. According to GMP validation studies are important part of GMP these are required to be done as per predefined protocols, the minimum that should be validated include process, testing and cleaning as a result such control procedure stablish to monitor the output and validation of manufacturing processes that may be responsible for variability of drug product. Validation is the one of the important part in achieving and maintaining the quality of the final product. The validation study provides the accuracy, sensitivity, specificity and reproducibility of the test methods employed by the firms, shall be established and documented. Process validation is the process for improving the safety and quality of the dosage form which is manufactured in the pharmaceutical industry. Process validation is an integral part of quality assurance as per cGMP. Validation and quality assurance will go hand in hand, ensuring the thorough quality for product. Process validation plays a key role in the pharmaceutical manufacturing process as it delivers a high degree of assurance and evidence that the process, which is being carried out gives out the uniform results, that is, it means the required specifications, which has been performed accurately. The purpose of this review is to present an introduction and general review on validation in pharmaceutical industry.
The 2022 Pakistan floods: Assessment of crop losses in Sindh Province using satellite data
Authors: Qamer Faisal Mueen , Ahmad Bashir , Hussain Abid , Salman Aneel , Muhammad Sher , Nawaz Muhammad , Shrestha Sravan , Iqbal Bilal , Thapa Sunil
Published: September 2022

The impact of the 2022 floods on Pakistan’s rural communities and agriculture has been devastating, resulting in the loss of crops, livestock, and essential infrastructure. The country is now facing an unprecedented food security crisis. Nationally, Pakistan’s Sindh Province accounts for 42% of the rice production, 23% of the cotton production, and 31% of the sugarcane production. In our report, we assess potential crop production losses for these crops at the sub-district level using a remote-sensing approach based on satellite imagery. The analyses are designed to support the Government of Pakistan's rehabilitation and compensation planning processes.
Settings for hyperkalemic patients in emergency department
Authors: Mohamed Sameh Ahmed Mahmoud
Published: September 2022

Background: Hyperkalemia is a common electrolyte disorder observed in the emergency department. It is often associated with underlying predisposing conditions, such as moderate or severe kidney disease, heart failure, diabetes mellitus, or significant tissue trauma. Additionally, medications, such as inhibitors of the renin-angiotensin-aldosterone system, potassium-sparing diuretics, nonsteroidal anti-inflammatory drugs, succinylcholine, and digitalis, are associated with hyperkalemia. To this end, Kidney Disease: Improving Global Outcomes (KDIGO) convened a conference in 2018 to identify evidence and address controversies on potassium management in kidney disease. This review aimed to summarize the deliberations and clinical guidance for the evaluation and management of acute hyperkalemia in this setting. The toxic effects of hyperkalemia on the cardiac conduction system are potentially lethal. The ECG is a mainstay in managing hyperkalemia. Membrane stabilization by calcium salts and potassium-shifting agents, such as insulin and salbutamol, is the cornerstone in the acute management of hyperkalemia. However, only dialysis, potassium-binding agents, and loop diuretics remove potassium from the body. Frequent reevaluation of potassium concentrations is recommended to assess treatment success and to monitor for recurrence of hyperkalemia.
Physiological and psychological variables among elite female athletes from three categories of sports and non-athletes
Authors: Aggarwala Jyotsna , Garg Rinku , Chatterjee Subhra
Published: September 2022

Background: The aim of the study was to categorize various body composition, physiological and psychological variables among Indian elite female athletes participating in endurance sports (Group A, n= 22, age= 17.01±0.99 years), combat sports (Group B, n= 20, age= 19.15±3.63 years) and skill sports (Group C, n= 25, age= 18.80±2.21 years) and non- athletic control group (Group D, N= 23, years= 18.34±1.87 years). Methodology: Physical parameters included body fat percent, lean body mass, muscle content and total water content. Physiological parameters included time domain and frequency domain parameters of heart rate variability and maximal aerobic power (VO2 max) measured using Astrand protocol. Various psychological parameters were evaluated using Big Five Inventory and State-Trait Anxiety Inventory questionnaires. Results: Discriminant analysis revealed three significant functions (P<0.05) contributing 78.2%, 13.2% and 8.7% respectively to the model. After cross validation, the resulting equation correctly classified 68.3% of endurance, combat, skill athletes and control group. Total eighteen variables significantly (P<0.05) contributed to the discriminant analysis. The interpretation of the acquired discriminant functions was also based on examination of the structure coefficients greater than 0.30.
Effects of Students’ Awareness on Developing Young Learners ‘listening skills at a foreign language center in Tra Vinh Province
Authors: Tran Thi Hong Nhi
Published: September 2022

During the integration period, English is rapidly asserting its importance. Four key abilities — listening, speaking, reading, and writing — are required to learn a language properly. The most important and challenging of these is listening. This current study was conducted to investigate the factors affecting the listening skills of young learners. The purpose of the study is to find out the factors that can help students improve their listening skills in particular and learn English well in general. The study was conducted at a language center in Tra Vinh province with the participation of 25 students from 12 to 15 years old who answered questionnaires about activities that can help students improve their listening skills. The Statistical Package for Social Sciences (SPSS) was used to analyze the data. The results show that many positive factors can help students develop listening skills, in addition to technology tools, students' awareness is an important factor. Besides, English outside the class (foreign language center) also helps students a lot in developing listening skills.
The early history of computer-assisted mathematics instruction for engineering students in the United States: 1965-1989
Authors: Semerikov Serhiy , Kiianovska Nataliia , Rashevska Natalya
Published: September 2022

The article discusses ICT development issues in teaching mathematics to engineering students in the United States. The nature of trends in the convergence of information systems in higher technical education and other tendencies in the United States are described in the article. The primary historical stages of computer-assisted mathematics training for engineering students in the United States are defined. The study of historical sources has allowed six stages to be recognized. The use of ICT for teaching mathematics is examined at each stage. It demonstrates the inconsistencies and key elements of using ICT to teach mathematics to engineering students. This article covers the first three stages (1965-1989) of computer-assisted mathematics training for engineering students in the United States.
Voorwaardelijke beëindiging van levenslang in Caribisch Nederland
Authors: Pesselse G.
Published: September 2022

Voorwaardelijke beëindiging van levenslang in Caribisch Nederland

In alle vijf de zaken stelt het Gemeenschappelijk Hof voorop dat beoordeeld moet worden of verdere onvoorwaardelijke tenuitvoerlegging van de levenslange gevangenisstraf geen redelijk doel meer dient. Dat centrale criterium sluit aan bij de wettekst en het kader van het EHRM. Het EHRM specificeert zelfs dat legitieme strafdoelen onder meer inhouden ‘punishment, deterrence, public protection and rehabilitation’. Tegen die achtergrond is opvallend dat in alle zaken wordt overwogen dat, gelet op de strafmotivering van de betreffende veroordelingen, ‘het’ doel van de opgelegde straf was om de maatschappij te beschermen tegen recidive van de veroordeelde (niet: het primaire, het belangrijkste).
De strijd om slachtofferschap
Authors: Daems Tom , Pemberton Antony , van Stokkom Bas
Published: September 2022

The struggle for victimhood – An introduction

In recent decades victims of crime have been receiving a lot of attention in science and policy. It gave rise to the development and flourishing of a separate discipline, victimology. The emphasis was on mapping victimization and fear of crime, the consequences of victimization, the development and evaluation of victim support, victims’ rights and newer forms of conflict resolution (e.g. restorative justice). Much victimological research was – and still is – focused on policy and improving the plight of victims of crime. However, more recently, we have seen a growing interest in studying victimization in a broader, societal context. This is done inter alia under the banner of a cultural victimology and in the wake of studies into processes of transitional justice, but also in the context of a socially critical debate about an alleged culture of victimization, therapy or complaint. It is such perspectives on victims and victimization that are at the center of this special issue on ‘cultures of victimhood’. The introductory article identifies and discusses some of the main developments and issues in this area of research and debate.
Plaatsen van terreur, mensenrechten en nationale identiteit
Authors: van Vree Frank
Published: September 2022

Places of terror, human rights and national identity

This essay analyses the global rise and various meanings of musealised prisons and torture centres. As sites of memory, they refer to painful, often gruesome episodes from the past. They use the same museum grammar, the roots of which can be traced back to the musealisation of Nazi concentration and extermination camps, in particular Majdanek at the end of the Second World War. Further research shows that despite the similarities in form, the meaning of all these memorial sites may vary widely. In a country like Argentina, these sites of terror are primarily symbols of crimes against humanity and human rights violations, while in the Baltic States and Hungary, among others, they primarily refer to a national victimhood; as theatres of remembrance, they are a source of national identity. The study of such places can give us a lot of insight into the political relations within, but also between countries.
Polish Achievements in Bioactive Compound Production From In Vitro Plant Cultures
Authors: Pietrosiuk Agnieszka , Budzianowska Anna , Budzianowski Jaromir , Ekiert Halina , Jeziorek Małgorzata , Kawiak Anna , Kikowska Małgorzata , Krauze-Baranowska Mirosława , Królicka Aleksandra , Kuźma Łukasz , Łuczkiewicz Maria , Malarz Janusz , Matkowski Adam , Stojakowska Anna , Sykłowska-Baranek Katarzyna , Szopa Agnieszka , Szypuła Wojciech , Thiem Barbara , Zielińska Sylwia
Published: September 2022

Plant cell and organ cultures are potential sources of valuable secondary metabolites that can be used as food additives, nutraceuticals, cosmeceuticals, and pharmaceuticals. Phytochemical biosynthesis in various in vitro plant cultures, in contrast to that in planta, is independent of environmental conditions and free from quality fluctuations.

Pharmaceutical application of plant biotechnology is of interest to almost all departments of the Faculty of Pharmacy and Institute of Pharmacology in Poland with a botanical profile (Pharmaceutical Botany, Pharmacognosy, and Pharmacology).

This study discusses the advances in plant biotechnology for the production of known metabolites and/or biosynthesis of novel compounds in plant cell and organ in vitro cultures in several scientific centers in Poland.
Gender accounting stereotypes in the highly feminised accounting profession. The case of Poland
Authors: Kabalski Przemysław
Published: September 2022

Purpose: The article presents the results of research on the frequency and content (varieties) of the stereotype that the accounting profession is a job for women. The research concerns Poland, a country with a unique level of feminisation of the accounting profession. Methodology/approach: To formulate hypotheses about the content (varieties) of the stereotype concerning the feminine character of accounting that exists in Poland, several mainly qualitative studies were carried out. As a result, four stereotypes were identified (i.e. different beliefs about why accounting is a profession for women and not for men). The hypotheses were tested using a survey of a representative group of Polish secondary school students (almost 1,200 respondents). Findings: The belief that the accounting profession is for women and not for men is expressed by one in six secondary school students, more often by men. Two stereotypes are particu-larly common: 1) that accounting is simply for women (without any specific justifica-tion), 2) that the most important aspects in this profession are accuracy, patience, meticulousness, the ability to focus on details, and other similar qualities usually attribut-ed to women. Originality/value: For the first time in Poland (and probably in other East European countries with feminized accounting profession), the article provides new and up-to-date knowledge on the gender perception of the accounting profession and the stereo-types about this job which may be a significant driving force in sustaining gender segre-gation in this profession.
Management of bakanae disease using fungicides and their effect on disease symptomatology
Authors: BASHYAL BISHNU MAYA , GUPTA ASHISH KUMAR , PARMAR POOJA , YADAV JAGDISH , CHOUDHARY RAVISH , KUMAR RAVINDRA , SINGH DHIRAJ , AGGARWAL RASHMI
Published: September 2022

Bakanae disease is an emerging problem of Basmati rice (Oryza sativa L.) in India and most of the basmati rice varieties are susceptible to this disease. Present study was carried out to evaluate and identify effective fungicide against bakanae disease of rice for which 12 fungicides (single and in combination) were evaluated against the bakanae disease as seedling treatments during the rainy (kharif) season of the year 2019 and 2020. Minimum disease incidence was observed with the fungicides Carbendazim 50% wp (19.47%), and Tebuconazole 50% + Trifloxystrobin 25% w/w 75 wg (25.71%) during the years of evaluation with maximum yield. Area under disease progress curve was minimum (621.58) with the treatment of Tebuconazole 50% + Trifloxystrobin 25% w/w 75 wg followed by Carbendazim 50% wp (671.30). Differences in bakanae disease symptoms were observed in different treatments. Among treatments, elongated tillers as major symptoms were observed in Mancozeb 75% wp, Zineb 68% + Hexaconazole 4% and Azoxystrobin 23% sc treated plants. Whereas, tiller elongation with rotting was prominent in Kitazin 48% ec treated and inoculated control plants. In case of Carbendazim 50% wp, Tebuconazole 8% + Captan 32% sc treatments, detachment of tillers was prominent. Therefore, seedling treatment with fungicides was observed to be effective in reducing bakanae disease incidence with low AUDPC and high yield compared to inoculated control.