bluuebunny/crossref_metadata_2025 huggingface dataset:
Starvation May Change the Type of Paternal but Not Maternal Inheritance of the Telomere Length Throughout Generations
Authors: Kalichman Leonid , Chumakova Anna M. , Torchinsky Arcady , Kobyliansky Eugene
Published: June 2022

Our aim was to evaluate the effect of starvation on the paternal and maternal inheritance of the leucocyte telomere length (LTL) in three birth cohorts: before, during, and after the Chuvashian famine of 1922–1923. This retrospective cohort study comprised native Chuvash men (n= 678) and women (n=647) born between 1909–1980. Data were gathered during three expeditions: 1994, 1999, 2002, enabling us to treat age and birth year as independent variables. LTL was measured by a quantitative polymerase chain reaction technique. A significant difference in LTL values (χ2 d.f=2=79.04, p<0.0001) was observed between the sexes. In a pedigree-based variance component analysis, ~67.4% of the LTL variation was explained by an additive genetic component. In the entire sample, a significant correlation was observed between the LTL of the parents and offsprings. Fathers born between 1924–1928 demonstrated a significantly stronger LTL correlation with their offsprings. The LTL correlation between mothers and offspring in this group and between parents and offspring in those born after 1928 did not differ from the entire population. We believe that the increased correlation between the LTL in the father-offspring pairs born after starvation in Chuvashia can be explained by differences in the processes of oogenesis and spermatogenesis in humans.
Functional Independence and Social Support as Mediators in the Maintenance of Mental Health among Elderly Persons with Chronic Diseases
Authors: Babić Dijana , Kamenečki Gordana , Milošević Milan , Završnik Jernej , Železnik Danica
Published: June 2022

The presence of chronic disease and lack of social support have negative impact on functional capacity in later life. The aim of this study was to determine the possible connections between the alteration in functional abilities and access to sources of social support with the occurrence of depression in elderly persons with chronic disease. A cross-sectional survey was conducted among 151 subjects with cardiovascular diseases at the age of 60 and above using standardized questionnaires. Groningen Activity Restriction Scale (GARS), Duke-UNC Functional Social Support Questionnaire (FSSQ), and Geriatric Depression Scale Short Form (GDS) were used to identify the presence of limitations in functional status, availability of social support and symptoms of depression. Multivariate binary logistic regression model was used to assess multivariate influence of significant variables on inclusion in the indicative depression group. Spearman’s rho coefficient was used to analyze correlation between GARS, GDS and FSSQ. GDS score ≥10 (indicative depression) was obtained by 15 (9.9%) participants and scores in the range 6–9 (suspected depression) by 21 (13.9%) participants. There were no significant correlations between the scores on the depression assessment scale and the sociodemographic characteristics of the participants. Binary logistic regression showed that with GARS increasing by a single unit, the chance of having depression significantly rises by 7% (OR: 1.07, 95% confidence interval (CI): 1.01–1.13; P=0.013) while when FSSQ increases by a single unit, that chance drops nearly 2.5 times (OR: 0.40, 95% CI: 0.23–0.70; P=0.001). The development of functional limitations and reduced level of social support are connected with the occurrence of depression. Creation of programs that will encourage the preservation of functional independence and enable effective social assistance can make a significant contribution to maintaining the mental health of elderly persons with chronic diseases.
Parteneriate pentru invatare. Experiente ale elevilor, profesorilor si scolilor
Authors: Alexandru Mirela
Published: June 2022

Lucrarea de fata analizeaza evolutia actiunii eTwinning in Romania si la nivel international in perioada 2012-2021. Au fost abordate experientele de parteneriate nationale si internationale din perspectiva participantilor in proiectele eTwinning, elevi si profesori, dar si din persoectiva efectelor extinse la nivelul institutiilor de invatamant.
Spontaneous rupture of secondary iris inclusion cyst causing acute glaucoma and other ocular sequelae
Authors: Shabto Julie M. , Price Kenneth W. , Allen John C. , Craven Caroline , Jones Jeremy K. , Wells Jill
Published: June 2022

A 63-year-old woman with a known secondary iris inclusion cyst in her right eye presented with headache, blurry vision, and eye pain of 3 days’ duration. Initial findings were notable for significant decrease in vision and elevated intraocular pressure in the right eye, with diffuse microcystic corneal edema, diffuse anterior chamber flare with minimal cellular reaction, and a significantly decompressed iris inclusion cyst. On gonioscopy, the right eye was open to scleral spur, and no pigment was visualized. Patient history and presentation were consistent with a diagnosis of spontaneous rupture of iris inclusion cyst causing secondary glaucoma. Iris inclusion cysts are not uncommon; however, ocular outcomes are generally benign and limited to obstruction of the pupillary axis.
Apparent metabolizable energy, growth performance and carcass traits of Japanese quail fed select modern grain sorghum varieties
Authors: Moritz A. H. , Krombeen S. K. , Presgraves J. , Blair M. E. , Buresh R. E. , Bridges W. C. , Arguelles-Ramos M. , Wilmoth T. A.
Published: June 2022

Objective: This study was performed to determine the apparent metabolizable energy (AMEn) content of tannin-free red/bronze, white/tan and U.S. No. 2 varieties of grain sorghum for feeding Japanese quail and validate their nutrient profile by evaluating effects on performance and carcass traits with full-substitution of corn.Methods: Experiment 1 determined the AMEn content of red/bronze, white/tan, and U.S. No. 2 grain sorghum varieties fed to mixed-sex Japanese quail (Coturnix japonica) (n = 314) at 3 and 6-weeks of age. Analyses were based on a 2×4 factorial treatment design with age and grain types defining the treatments, and a randomized complete block experiment design with cage and trials defining the block. AMEn values were validated by evaluating the performance and carcass traits of Japanese quail (n = 644) from 1 to 40 days of age in Experiment 2 with birds were fed 1 of 4 complete diets. Statistical analyses were conducted on performance data and select individual carcass trait measurements.Results: Determined AMEn values at 3-weeks of age were 3,524±122.03 (red/bronze), 3,252±122.03 (white/tan), and 3,039±123.44 (U.S. No. 2) kcal/kg. At 6-weeks of age, determined AMEn were 3,373±297.35 (red/bronze), 3,279±297.35 (white/tan), and 2,966±298.64 (U.S. No. 2) kcal/kg. Carcass traits showed live body weight (p = 0.0409) and hot carcass weight (p = 0.0234) were greatest in U.S. No. 2; however, carcass yield (p<0.0001) was lowest. No significant differences were observed among treatments for feed intake, feed conversion ratio, breast weight and breast yield (p>0.05).Conclusion: These studies demonstrated that tannin-free grain sorghum varieties may be a potential alternative to corn in quail diets while maintaining growth performance and carcass parameters.
UMA QUESTÃO RACIAL:
Authors: Coelho Allyson Camilo Nascimento
Published: June 2022

O objetivo dessa pesquisa é analisar a racialização da cidadania, particularmente no atual contexto histórico de políticas neoliberais, que se dá a partir da década de 1980, no Brasil. Para esta análise será esboçado a concepção de cidadania, interligada à construção discursiva na ideia de raça e de gênero, sobretudo na permanência do discurso do mito da democracia racial. Estas narrativas legitimam as desigualdades raciais e sociais, bem como a segregação e a política de morte sobre os sujeitos racializados. Para tal contexto, analisaremos a partir do paradigma da Afrocentricidade, visto como uma “crítica à dominação cultural e econômica europeia”, tendo como paradigma a “correção no reposicionamento do africano como sujeito de sua própria história”.  Este ponto de vista se legitima devido ao fato de que o “deslocamento físico dos africanos durante o comércio europeu de escravos, fomos afastados de nossos centros culturais, psicológicos, econômicos e espirituais e colocados à força na cosmovisão e no contexto europeus (ASANTE, 2016, p. 10)”. Compreendemos que ela nos ajuda a analisar a historicidade dos problemas sociais que tangenciam assuntos não somente econômicos e políticos, como também as questões culturais, as relações raciais, as relações de classe e as relações de gênero. Fontes derivadas das análises desenvolvidas pelo Ipea e pelo Fórum Brasileiro de Segurança Pública (FBSP), o Atlas da Violência 2019, serão de suma importância, já que possibilitam compreender o índice de violência e de desigualdades, no Brasil. A perspectiva tomada por Achille Mbembe, de necropolítica, em que a soberania do Estado limita-se a quem deve viver e a quem deve morrer, será também nosso suporte para a análise. Diante dos levantamentos bibliográficos colocamos em sobre a possibilidade e a necessidade de reformulação de um novo conceito ou paradigma e aplicabilidade de Cidadania a partir de perspectivas e referências não eurocêntricas. Isso significa que é necessário “retornar às civilizações clássicas da África para inspiração e orientação (ASANTE, 2016, p. 13).”
REPRODUÇÃO ARTÍSTICA MUSICAL NO CENÁRIO DA PANDEMIA DE COVID-19
Authors: Cunha Gabriel Juan de Oliveira , Medeiros Regina de Paula , Torres Caio Buono
Published: June 2022

A proposta deste artigo é apresentar uma pesquisa sobre a expressão artística, particularmente da música, moldada com caráter particular no cenário contemporâneo, marcado pela pandemia mundial causada pela Covid-19. O objetivo é analisar o cenário artístico musical que se formou durante a extensão da pandemia causada pelo novo coronavírus, com enfoque na representação artística da realidade experenciada pelos artistas e a sua relação com as experiências individuais no contexto do isolamento social. O estudo foi realizado no período de isolamento social, particularmente nos meses de maio e junho de 2020. Foram analisadas as redes sociais, os fóruns de debates anônimos e não anônimos, os sites e os grupos musicais. A partir do material obtido em campo, foram selecionadas 11 músicas nacionais e internacionais. Conclui-se que a música, especialmente no momento escolhido, é capaz de contribuir para a identificação de diferentes agrupamentos sociais nos mais diversos territórios do mundo. Pode-se afirmar que a música tem um significado específico e é uma ferramenta política e social. Nesse contexto mundial tão peculiar e sem precedentes, pode reduzir as mazelas e as vulnerabilidades ao apontar que o altruísmo é possível, representa alívio para os seres humanos e pode contribuir para a construção de laços sentimentais afetivos e sociais, ainda que por meio do sofrimento social.
Evaluating Similarity of Spectrogram-like Images of DC Motor Sounds by Pearson Correlation Coefficient
Authors: Ciric Dejan G. , Peric Zoran H. , Milenkovic Marko , Vucic Nikola J.
Published: June 2022

Three main approaches on how audio signals can be used as input to a deep learning model are: extracting hand-crafted features from audio signals, mapping audio signals into appropriate images such as spectrogram-like ones, and using directly raw audio signals. Among these approaches, the usage of spectrogram-like images represents a compromise regarding the bias enforced by the processing (seen in hand-crafted features) and computational demands (seen in raw audio signals). When any of the spectrogram-like images is used as a deep learning model input, then different techniques for image processing become available and can be implemented. They include techniques for assessing the image similarity, implementing image matching, and image recognition. The topic of this paper is similarity of spectrogram-like images obtained from DC motor sounds. In that respect, relevant measures of image similarity are first reviewed, and then one of them - the Pearson correlation coefficient - is applied for evaluating the similarity within the same class and between two classes of different spectrogram-like images.
Der fehlerhaft angewiesene GmbH-Geschäftsführer
Authors: Götz Johannes
Published: June 2022

Illegal instructions are not to be followed! – However, it is probably not quite that simple in practice: An incorrectly instructed executive director of a GmbH (limited liability company) is threatened with serious consequences if he either refuses to carry out the instruction or carries it out in breach of his duty. He finds himself in a state of tension between personal responsibility and the obligation to follow instructions. The thesis examines the risk of the executive director and his options for action if he doubts the legality of an instruction. With the remonstration he succeeds in freeing himself from this dilemma and in returning the responsibility to the instructor without having to resign from his office as executive director.
Inhalts- und Nebenbestimmungen in Genehmigungen von Windenergieanlagen
Authors: Frey Michael , Kron Mirco , Weigel Alix
Published: June 2022

Following a legal and economic evaluation of all wind turbine autorisations issued in Baden-Württemberg between 2012 and 2017, this working aid shows – in addition to the requirements to be observed – optimal text modules for side regulations in all relevant legal areas. It thus offers an indispensable working aid in the important field of the legally secure expansion of wind energy – this also beyond the borders of the administrative practice in Baden-Württemberg.
Statistisches Jahrbuch der Anwaltschaft 2021/2022
Authors: Kilian Matthias
Published: June 2022

Das aktuelle Statistische Jahrbuch 2021/2022 dokumentiert die Entwicklungen auf dem anwaltlichen Rechtsdienstleistungsmarkt und die Veränderungen der Strukturmerkmale des anwaltlichen Berufsbildes. Das Jahrbuch konsolidiert Daten zur Anwaltschaft sowohl anderer Institutionen als auch der Forschungstätigkeit des Soldan Instituts. Es bietet empirisches Material zu Gegenwartsbefunden und, über weit zurückreichende Datenreihen, zu langfristigen Entwicklungen.

Jedes der 11 Kapitel gliedert sich in einen erläuternden Einführungstext und einen ausführlichen Tabellenteil. Das ermöglicht dem Leser einen schnellen und präzisen Überblick über die zum Markt anwaltlicher Dienste vorhandenen Daten.

Rund 200 Tabellen enthalten Datenmaterial zu folgenden Themen:

Basisdaten der Anwaltschaft

Regionale Verteilung der Anwaltschaft

Innere Differenzierung der Anwaltschaft

Organisationsformen der Anwaltschaft

Wirtschaftliche Situation der Anwaltschaft, Ausbildung, Berufseinstieg, Arbeitslosigkeit von Juristen, Finanzierung anwaltlicher Leistungen, Institutionen der Anwaltschaft, Grenzüberschreitende Tätigkeit von Rechtsanwälten, Der Anwaltschaft benachbarte Berufe, Geschäftsentwicklung der Gerichte.
Response of Some Hematologic Factors to Single Session of CrossFit Exercise in Professional Male Athletes
Authors: Kashef Alireza , Zare Karizak Sara , Sadeghi Nikoo Alireza , Kashef Majid
Published: June 2022

Background: High-intensity exercise is one of the effective factors in hematologic changes. Objectives: The purpose of this study was to determine the effects of a single session of CrossFit exercise on platelets (Plts), red blood cells (RBCs), white blood cells (WBCs), hemoglobin (Hb), hematocrit (Hct), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), and mean corpuscular hemoglobin concentration (MCHC) in professional male athletes. Methods: Thirty-two male athletes were selected as subjects (with mean age 26.9 ± 4.7 years, height 177 ± 5 cm, weight 80.7 ± 6.4 kg). The CrossFit exercise session consisted of running for 400 meters, three-stage deadlifting, pull-up (30 repetitions), 30 kg kettlebell swinging, and throwing 20 sand balls. Blood sampling and CBC tests were used to measure hematologic indices. The biochemistry auto analyzer also was used to measure lactate as a witness variable. In addition, ANOVA with repeated measures and Bonferroni post hoc tests were used to examine the differences between variables in resting position, post-exercise, and after correction for the volume of plasma lost. Results: The results of the present study showed a significant increase in lactate, Plts, and WBCs (P < 0.0001). However, there were significant decreases in RBCs, Hct, Hb, MCV, MCH, and MCHC (P < 0.0001). Conclusions: A single session of CrossFit exercise causes disorder in hematologic responses of professional male athletes. So, it is recommended to have enough time to recover after this type of exercise.
Autonomous DataFactory: High-throughput screening for large-scale data collection to inform medicine manufacture
Authors: Pickles Thomas , Mustoe Chantal , Brown Cameron , Florence Alastair
Published: June 2022

Using small-scale crystallisation to inform downstream processes, we can reduce time and material costs in medicine manufacturing. This work introduces a preliminary workflow for information-rich data collection of crystallisation parameters including solubility, induction time, growth rate, secondary nucleation rate, particle shape and size. Large-scale data collection was achieved for 6 active pharmaceutical ingredients (APIs) in 31 solvents in less than 9 months with the results for aspirin presented here. Highlights include the identification of 24 potential alternative crystallisation solvents for manufacturing aspirin, all of which yield the biorelevant polymorph. Automation of this workflow will enable the use of robotics to further reduce time and material usage when conducting crystallisation experiments for future APIs.
Physicochemical and biopharmaceutical characterization of new sulfonamide derivatives of gallic acid
Authors: Alhyari Dania Hussein , Sheldrake Helen Sheldrake , Kantamneni Sriharsha , Isreb Mohammad , Soumehsaraei Shohreh Jafarinejad , Martin William , Qinna Nidal , Paluch Krzysztof
Published: June 2022

Gallic acid (GA) is known for its antioxidant activitywhichis restricted due to its low oral permeability. In this project the carboxylic group of (GA) was substitutedwith sulfonamide group and hydroxyl groups were methylated which resulted insignificantly (p<0.01) increased permeability of 3,4,5-trimethoxybenzenesulfonamide (TMBS) and 3,4,5-trihydroxybenzenesulfonamide (THBS) over GA, inParallel Artificial Membrane Permeability Assay studies with simulatedgastrointestinal fluids and Human intestinal epithelial cells HIEC-6 cells.Biochemical studies confirmed TMBS was O-demethylated by CYP2D6. THBS and GAhad increased antioxidant activity with increased concentration in DPPH assaywhile TMBS indicated lower activity at all tested concentration. Theantioxidant activity of TMBS was greater than GA in HIEC-6 cells which mainlyrelated to its O-demethylation by CYP2D6. 
GERMAN PARTICIPATION IN THE THREE SEAS INITIATIVE: OPPORTUNITIES FOR RUSSIA
Authors: Khorolskaya Maria V.
Published: June 2022

The Three Seas Initiative was launched in 2016 by the Polish and Croatian leaders to bridge the gap between Southeast, Central and Eastern Europe, on the one hand, and Western Europe, on the other. This article aims to show how German policy on the Three Seas Initiative has changed and what risks and opportunities it represents for Russia. The official data on the Three Seas Initiative was used to explore the specifics of the concept and the impact of its most promising projects on the Southeast, Central and Eastern European markets. The ana­lysis of materials from German think tanks and the Ministry of Foreign Affairs was used to demonstrate the changes in Germany's attitude towards the Initiative. Although the participating countries have not received sufficient funding to fulfil all the ambitious goals of the Three Seas Initiative, some of its most promising projects could diminish Russia’s role in the EU energy market. Since 2018, the Federal Republic of Germany has increased its participation in the Initiative, yet Berlin’s growing focus on the concept should not be perceived critically since German participation could mitigate the anti-Russian sentiment underlying the Three Seas Initiative. Moreover, the ideas voiced by Germany’s Free Democratic Party, namely those concerning a joint hydrogen project with Russia to be run as part of the Three Seas Initiative, deserve special attention.
Parental and non-parental figures of attachment as predictors of affective styles
Authors: Lazović Nataša , Marković Emilija
Published: June 2022

Emotional regulation is one of the components of emotional intelligence that is very important for the development of the person and the quality of life in adulthood. Growing up, in a relationship with family, then with peers and finally with partners, we learn to regulate our emotional experiences and build characteristic affective styles. The aim of this paper is to examine whether there is an interdependence of figures of attachment in the prediction of affective styles in a sample of young adult girls who are currently in a partnership and those who are not (264 respondents). The instruments used were: Questionnaire for assessing partner, friend and family attachment - three versions (Kamenov, Jelić 2003). This questionnaire is a revised Croatian version of the ECR (Experience in Close Relationship Questionnaire) questionnaire (Brennan, Clark, Shaver 1998) and the ASQ Affective Style Questionnaire (Hofmann, Kashdan 2010). The connection between affective styles and attachment for all three examined figures was confirmed, as well as the predictive power of some dimensions of attachment in the explanation of affective styles. The initial hypotheses of this paper are only partially confirmed, but the results indicate important theoretical and practical implications that could be supplemented in future work. Attachment is obviously an important part in the space of emotion regulation, but it seems that the correlation is not direct and that there is an influence of many personal and situational variables that need to be researched in future
Investigating critical factors influencing the acceptance of e-learning during COVID-19
Authors: Nedeljković Ivana , Rejman-Petrović Dragana
Published: June 2022

Background: In order to prevent the spread of the Covid-19 virus, a temporary interruption of teaching and educational activities in classrooms occurred. Most schools and faculties were forced to switch from traditional to online teaching. Purpose: This research aims to examine the key factors influencing students' intention to use e-learning, as well as predictors of student satisfaction with online teaching during the Covid-19 pandemic. Study design/methodology/approach: The analysis includes 312 students on the territory of the Republic of Serbia who use e-learning. Reliability analysis, confirmatory factor analysis and structural equations modeling are applied in the paper. Findings/conclusions: It is found that course design significantly affects perceived usefulness, perceived ease of use and quality of e-learning, and perceived usefulness and quality of e-learning are the main drivers of student satisfaction. Then, perceived usefulness, perceived ease of use and satisfaction with online teaching are important predictors of the attitude towards the use of e-learning, and attitude is an important driver of the intention to use e-learning. The results of the research and the implications derived from them can be helpful to educational institutions in creating, introducing and implementing e-learning, as well as increasing student satisfaction with online teaching during the pandemic. Limitations/future research: The limitation of the research stems from the selection of the sample (students). In addition, the research was conducted on the territory of Serbia, so the results cannot be generalized. Third, the possible bias of the respondents in giving answers can lead to wrong conclusions. The recommendation for future research is to examine the attitudes of professors who use e-learning, in addition to students. Another recommendation is to do a segment analysis (by gender, year of study) in order to develop specific strategies for each segment. Another suggestion is to compare students' opinions on e-learning and traditional ways of learning.
Property P in modular metric spaces
Authors: Paunović Ljiljana , Kumar Parveen , Malik Savita , Kumar Manoj
Published: June 2022

Introduction/purpose: The aim of this paper is to present the concept of the generalized ∅-weak contractive condition involving various combinations of d(x,y) in modular metric spaces. Methods: Conventional theoretical methods of functional analysis. Results: This study presents the result of (Murthy & Vara Prasad, 2013) for a single-valued mapping satisfying a generalized ∅ -weak contractive condition involving various combinations of d(x,y). It is generalized in the setting of modular metric spaces, and then it is proved that this single-valued map satisfies the property P. In the end, an example is given in support of the result. Conclusion: With proper generalisations, it is possible to formulate well-known results of classical metric spaces to the case of modular metric spaces.
New combinatorial proof of the multiple binomial coefficient identity
Authors: Stojiljković Vuk
Published: June 2022

Introduction/purpose: In this paper a new combinatorial proof of an already existing multiple sum with multiple binomial coefficients is given. The derived identity is related to the Fibonacci numbers. Methods: Combinatorial reasoning is used to obtain the results. Results: The already known identity was obtained by using a new combinatorial reasoning. Conclusions: The new combinatorial reasoning led to the solution of the already existing identity.
Fixed point theorem in a partial b-metric space applied to quantum operations
Authors: Tiwari Rakesh , Saeed Khan , Rani Shoba , Fabiano Nicola
Published: June 2022

Introduction/purpose: A fixed point theorem of an order-preserving mapping on a complete partial b-metric space satisfying a contractive condition is constructed. Methods: Extension of the results of Batsari et al. Results: The fidelity of quantum states is used to construct the existence of a fixed quantum state. Conclusions: The fixed quantum state is associated to an order-preserving quantum operation.
Malicious code in the cloud
Authors: Damjanović Dragan
Published: June 2022

Introduction/purpose: The paper analyzes the impact of malicious codes in the cloud. Malicious code is an unauthorized piece of code that violates the integrity of an application and infrastructure to cause certain effects, such as security breaches, spread of infections, and data infiltration from the computer with the help of malicious software - this is a simple form of data theft which can lead to disastrous consequences in all segments of society, especially when it comes to national security. To overcome this challenge, it is necessary to detect holes in the safety of cloud environments and repair them before the attackers use these vulnerabilities to bypass the integrated cloud infrastructure. Methods: Structural analysis, functional analysis, comparative analysis, synthesis. Results: There are many factors for collecting, comparing, and delivering intelligence data on cloud threats. Cloud applications are increasingly being targeted because their use to store and share data with mobile application hosting has been increased exponentially, enabling industrial automation and business information monitoring and procurement. In addition, billions of devices on the Internet use the cloud infrastructure as a background for processing and transmitting large data sets. Malicious code is easily distributed due to the ease of sharing documents and files via the cloud. Conclusion: As cloud technologies are taking a central place in the world of digital transformation, the threat to the cloud environment is expected to grow exponentially. This means that organizations need to ensure that the cyber security position of the cloud infrastructure they possess is robust and mature enough to combat all relevant security threats in order to minimize business risks. Understanding the nature of practical security controls and how they are assessed enables organizations to build a practical approach to security and privacy in the cloud.
Design and implementation of a smart sterilizing device to solve the doorknob contamination problem
Authors: Abdulrahman Satam , Zaenal Mohammed
Published: June 2022

Introduction: In 2020, the World Health Organization announced that Corona virus (Covid-19) is a global pandemic. Since then, social distancing and sterilization have become essential as precaution measures to decrease the infection. The risk of Covid virus spread led people, industries as well as governments to implement several approaches to control the transmission rate of the virus. During their daily life activities such as work, shopping, eating, etc. people touch a lot of surfaces and also open a large number of doors. This is considered to be one of the fastest ways to spread viruses because many people touch door handles which are generally rarely cleaned. Method: In this paper, the implementation of a cost-effective smart device has been presented. The device sprays ethanol onto a doorknob from an ethanol sterilizer after any person touches the knob. The sensor detects a hand touching the knob, after that a signal is sent to the Arduino for processing, and then after a 4.5-sec delay, the Arduino sends a signal to the water pump to pump ethanol alcohols through the nozzle directly to the knob. Results: The device shows precise and accurate results regarding the number of uses and the temperature of the surrounding ambient. Conclusion: The system is applicable in offices and public buildings. Due to its functionality, it can be of great assistance in decreasing the contamination of doorknobs.
Tragedia civil y metamorfosis de la razón en María Zambrano
Authors: Cerezo Galán Pedro
Published: June 2022

La Guerra Civil fue una experiencia decisiva en la evolución del pensamiento de María Zambrano. Entendida y vivida como una tragedia cuyo sujeto es el pueblo, personificación de lo más elemental de la condición humana en su lucha contra el fascismo, esa experiencia abolió cualquier razón en clave idealista y reductora de la vida. En su lugar y en diálogo íntimo con la poesía de Antonio Machado, Zambrano elaborará una razón amorosa que retoma su reflexión anterior a la guerra y la proyecta hacia una razón poética que, ya en el exilio y ante la imposibilidad de una redención de la tragedia, tendrá que orientarse hacia una interioridad radical
Del exilio español a la filosofía mexicana. Un trayectoria más que intelectual
Authors: Sánchez Cuervo Antolín
Published: June 2022

Entrevista con María del Carmen Rovira Gaspar
El pensamiento español sufrió un retraso con motivo de la Guerra Civil y el exilio de los mejores pensadores
Authors: Morollón del Río Diego
Published: June 2022

Entrevista a José Luis Abellán
Los significados acerca de la formación y profesionalización docente universitaria de los profesores de bachillerato y licenciatura de la UNAM.
Authors: De Agüero-Servín María de las Mercedes , Rendón-Cazales Víctor Jesús , Benavides_Lara Mario
Published: June 2022

Introducción. La investigación del papel de los docentes en la educación universitaria como actores principales que intervienen en los procesos educativos que ocurren en las aulas tiene décadas. El trabajo docente es complejo pues está atravesado por diferentes factores que median sus acciones y decisiones. Los profesores adoptan diferentes posiciones que se contraponen, se reafirman y negocian en las interacciones con sus pares y estudiantes. Método. El presente trabajo es un estudio cualitativo con ocho grupos focales que tiene como objetivo mostrar los actos de significado (Bruner, 1990) que construyen algunos docentes de bachillerato y licenciatura de la Universidad Nacional Autónoma de México (UNAM), acerca de la docencia y su formación profesional para la enseñanza, según las relaciones que establecen con otros profesores y estudiantes. Resultados. Las participaciones del profesorado en los grupos focales se analizaron evidenciando diversos recursos discursivos que construyeron significados en relación con dos enfoques y tipos específicos de concebir a la docencia y la formación docente: el monológico y el dialógico. Conclusiones. Entre las principales conclusiones se encuentra que los significados acerca de la docencia y la formación docente se entienden como cualidades y movimientos en las relaciones entre los actores involucrados en las prácticas educativas. El enfoque monológico da cuenta de tres significados fundamentales: el de la docencia contenciosa, la idealizada y la centrada en la didáctica; mientras que el enfoque dialógico se construye en movimientos de tres tipos: la docencia colaborativa, la reflexiva y la inclusiva.
La formación de profesionales cubanos en el contexto empresarial
Authors: Mena-Lorenzo Juan Alberto , Merna Lorenzo Jorge Luis
Published: June 2022

El artículo abordó un problema latente en la Educación Técnica y Profesional cubana, relacionado con la formación profesional de estudiantes de escuelas politécnicas en contextos empresariales. Su objetivo general fue caracterizar la evolución histórico-lógica de dicha formación estableciendo en cada modelo implementado el comportamiento de categorías esenciales que alcanzan el estatus de núcleos conceptuales, como: proceso de enseñanza-aprendizaje, proceso profesional e integración escuela politécnica-empresa. La investigación tuvo un enfoque cualitativo de carácter explicativo, apoyándose en métodos del nivel teórico y del nivel empírico que permitieron el análisis y caracterización de los modelos implementados en los últimos 60 años de Educación Técnica y Profesional cubana, demostrándose la mayor validez en el modelo de formación profesional compartida.  
Palabras clave: Educación Técnica y Profesional, escuela politécnica, empresa.
La autonomía escolar en Europa: aportaciones para la innovación educativa
Authors: Ortega-Rodríguez Pablo Javier
Published: June 2022

La autonomía escolar es un factor clave para impulsar procesos de innovación en los centros educativos. Su desarrollo en los países europeos ha experimentado cambios notables en función de la política educativa, lo cual exige un estudio específico sobre las aportaciones al ámbito de la teoría y la práctica educativa. El objetivo de este artículo es conocer el efecto de la autonomía escolar en la innovación educativa a partir de una crítica argumentativa sobre los avances que han realizado los países europeos con diferentes trayectorias en innovación: España, Francia, Reino Unido. Bélgica, Alemania y Finlandia. Se justifica la relevancia de la autonomía escolar en el panorama educativo actual para promover la capacidad de desarrollo interno de los centros y ofrecer una respuesta adaptativa y personalizada a las necesidades del alumnado. Se ahonda en el significado del concepto y los diferentes modelos que se dan en la práctica educativa. En España, los avances se han realizado en la metodología por parte del profesorado, mientras que en Francia, las decisiones sobre los contenidos y la metodología competen a la Administración y la dirección escolar. Reino Unido aboga por la autonomía orientada a los resultados académicos, en busca de la eficacia. Bélgica cuenta con una amplia experiencia en la autonomía escolar para elegir los contenidos y los métodos educativos. En Finlandia y Alemania, los organismos municipales gestionan la innovación de los centros. Los resultados del análisis de la autonomía escolar en estos países europeos ponen de relieve que, a pesar de los progresos, aún existe una brecha entre el discurso teórico de la autonomía y su aplicación en la práctica educativa. En este estudio, se realizan propuestas que contribuyen a superar esta brecha en cualquier contexto y gestionar la autonomía escolar para impulsar procesos de innovación.
La educación como derecho: acuerdos, agendas y alcances en la región latinoamericana
Authors: Lorente Rodríguez Miriam , Ruiz Guillermo Ramón
Published: June 2022

INTRODUCCIÓN. La educación como derecho ocupa un rol destacado en su reconocimiento internacional por parte del derecho internacional de los derechos humanos y de los Estados. Sin embargo, se deben estudiar sus condiciones de vigencia para evitar generalizaciones. La definición conceptual del derecho merece ser estudiada a la luz de los desarrollos normativos supraestatales y locales, así como de sus políticas. MÉTODOS. En este artículo se analizan algunos de los compromisos internacionales y regionales que se han suscrito en América Latina a partir de la década de 1970 así como también series estadísticas hasta el año 2015. RESULTADOS. En primer lugar, se propone una definición del derecho como esquema de investigación a la educación como derecho humano fundamental. En segundo lugar, se analizan los compromisos internacionales en la región latinoamericana para proponer un estudio en particular del derecho a la educación y sus alcances normativos en este contexto. DISCUSIÓN. Se advierte que, si bien la región ha avanzado en acuerdos supraestatales en relación con este derecho humano, incluso con anterioridad a la agenda global de 1990 (con una marcada diseminación en el plano de la normatividad) ello no se evidencia en el plano de la efectividad, en función de los resultados en cuanto escolarización
Preference of online friends over face-to-face friends: Effect of interpersonal fears on online relationship building preference
Authors: Shabahang Reza , Aruguete Mara S. , Shim Hyejin , Mokhtari Chirani Benyamin
Published: June 2022

The emergence of online social networking has increased development of exclusively online friendships. Individuals in online environments are willing to invest considerable time and effort to develop and maintain relationships as they would in other gathering spaces. In some cases, individuals find it preferable to make friends via the internet over more traditional means of relationship formation. The current study examines preference for online friends over face-to-face friends. Initially, we developed a brief, one-dimensional, 11-item questionnaire assessing online friendship preference based on semi-structured interviews. Confirmatory factor analysis showed support for a one-factor model. Internal consistency was established using inter-item correlation, corrected item-total correlation, and Cronbach’s α. Subsequently, we examined the psychological determinants and consequences of preference for online friendship formation. Participants who reported higher fear of intimacy and perceived relationship vulnerability reported greater preference for online friends over face-to-face friends. Preference for online friendship was related to increased risk of problematic internet use. The findings suggest that interpersonal fears, combined with attributes of online communication (e.g., reduced social cues and more personal control) motivate some individuals to prefer online intimacies over face-to-face friendships, thereby increasing time spent online.
Changes in lifestyle and obesity during the COVID-19 pandemic in Korean adolescents: based on the Korea Youth Risk Behavior Survey 2019 and 2020
Authors: Kang Sinyoung , Seo Moon Young , Kim Shin-Hye , Park Mi Jung
Published: June 2022

Purpose: The coronavirus disease 2019 (COVID-19) pandemic has affected people's daily lives and increased their time spent at home. This study aims to investigate the changes in lifestyle factors and obesity among Korean adolescents before and during the COVID-19 outbreak.Methods: We used the data of 109,282 adolescents aged 12–18 years, from the Korea Youth Risk Behavior Survey conducted in 2019 and 2020 before and during the COVID-19 pandemic, respectively. The changes in the prevalence of obesity and lifestyle factors (diet, exercise, sitting time, and sleep duration) were assessed. The adjusted odds ratios (ORs) (95% confidence intervals [CIs]) of predictors for obesity were calculated.Results: The prevalence of overweight (10% to 10.5%) and obesity (11.5% to 12.7%) increased significantly, especially among males younger than 15 years, whereas significant differences were absent among females. The mean body mass index z-score increased from 0.28 to 0.39 in males but decreased from 0.08 to 0.04 in females. Fruit consumption, regular exercise, and average sleep duration decreased, whereas sitting time increased. After controlling for covariates, a short sleep duration (OR, 1.14) and an increased sitting time (OR, 1.14) were significantly associated with an elevated risk for overweight/obesity.Conclusion: During the COVID-19 pandemic, the prevalence of obesity and overweight increased, particularly in males, as did unfavorable trends in related lifestyle factors. Sex- and age-specific strategies to improve lifestyle factors associated with obesity are needed, especially during the COVID-19 pandemic.
Metanephrine negative pheochromocytoma: a rare case report of dopamine-secreting tumor in an adolescent neurofibromatosis type 1 patient
Authors: Lee Mi-Seon , Lee Rosie , Park Sook-Hyun , Kwon Soon Hak , Park Jin-Young , Lee Sang-Woo , Lee So-Mi , Moon Jung-Eun
Published: June 2022

Pheochromocytoma (PCC) occurs in 4% of pediatric neurofibromatosis type 1 (NF1) patients and is characterized by epinephrine and norepinephrine secretion. Herein, we report the first case of dopamine-secreting PCC in a 13-year-old patient with NF1. A left adrenal mass was incidentally found on abdominal computed tomography (CT ) during hypertension workup. Fractionated 24-hour urine metanephrine excretion was normal, but urine dopamine level was elevated. Focal 123I-metaiodobenzylguanidine uptake was observed on single-photon emission tomography/CT (SPECT/CT). Surgery was delayed due to small tumor size, vague symptoms, and increased dopamine level. After 6 months, focal significant uptake of the lesion on 6‐[18F]fluoro‐L‐3,4‐dihydroxyphenylalanine (18F-FDOPA) PET/CT increased and tumor size increased on abdominal CT. Laparoscopic resection was performed, and the mass was histologically confirmed as PCC. Currently, the vital signs of the patient are stable, urine dopamine level is normal, and there is no abnormal uptake of 18F-FDOPA PET/CT. This study reports a rare case of dopamine-secreting PCC. A multidisciplinary approach and focused examination are needed in metanephrine-negative, high-risk PCC patients.
Factors affecting bone mineral density in children and adolescents with secondary osteoporosis
Authors: Jang Min Jeong , Shin Chungwoo , Kim Seongkoo , Lee Jae Wook , Chung Nack-Gyun , Cho Bin , Jung Min Ho , Suh Byung-Kyu , Ahn Moon Bae
Published: June 2022

Purpose: This study aimed to investigate the clinical factors associated with bone mineral density (BMD) among children and adolescents with osteoporosis secondary to treatment for underlying clinical conditions.Methods: We retrospectively reviewed the medical records of patients aged 10–18 years and evaluated them for lumbar spine BMD (LSBMD) after treatment for underlying diseases, including hemato-oncologic, rheumatologic system, and inflammator y bowel diseases. LSBMD measured by dual-energy x-ray absorptiometry (DXA) performed from March 2019 to March 2021 was evaluated. We analyzed 117 patients who underwent initial DXA after treatment for underlying diseases.Results: Subjects in this study had multiple underlying diseases: hemato-oncologic (78.6%), rheumatologic (11.1%), and inflammatory bowel diseases (10.3%). There was no significant association between the z-score and bone metabolic markers (P>0.05). However, higher cumulative glucocorticoid (GC) dose significantly reduced LSBMD z-score (P=0.029). Moreover, the association between cumulative dose of GC and initial z-score of LSBMD was significant in logarithmic regression analysis (P=0.003, R2=0.149). GC accumulation was a significant risk factor for vertebral fracture when the initial BMD was evaluated after treatment (P=0.043). Bone metabolic markers did not significantly influence the risk of vertebral fracture.Conclusion: Initial bone mass density of the lumbar spine evaluated after long-term GC use for underlying diseases is a predictor of further vertebral fractures.
Risk factors of postoperative hypoparathyroidism after total thyroidectomy in pediatric patients with thyroid cancer
Authors: Choe Yunsoo , Lee Yun Jeong , Shin Choong Ho , Chung Eun-Jae , Lee Young Ah
Published: June 2022

Purpose: Hypoparathyroidism (hypoPTH) is the most common complication following thyroidectomy. We investigated the frequency and risk factors of hypoPTH after total thyroidectomy (TT) in pediatric patients with thyroid cancer.Methods: This retrospective study included 98 patients younger than 20 years who were diagnosed with thyroid cancer after T T during 1990–2018 and followed for more than 2 years at Seoul National University Hospital. HypoPTH was defined as receiving active vitamin D (1-hydroxycholecalciferol or 1,25-dihydroxycholecalciferol) after surgery.Results: The study included 27 boys (27.6%) and 71 girls (72.4%). The mean age at diagnosis was 14.9±3.7 years. HypoPTH occurred in 43 patients (43.9%). Twenty-one patients (21.4%) discontinued active vitamin D less than 6 months after surgery, while 14 (14.3%) continued active vitamin D for more than 2 years. Tumor multifocality (odds ratio [OR], 3.7 vs. single tumor; P=0.013) and preoperative calcium level (OR, 0.2; P=0.028) were independent predictors of hypoPTH immediately after TT. In addition, age (OR, 0.8; P=0.011) and preoperative calcium level (OR, 0.04; P=0.014) significantly decreased the risk for persistent hypoPTH requiring active vitamin D for more than 2 years.Conclusion: HypoPTH occurred in 43.9% of pediatric thyroid cancer patients after TT in this study. Among them, one-third of patients continued active vitamin D medication for more than 2 years, which was predicted by young age and low preoperative calcium level.
ORAL SOFT TISSUE KERATOCYST
Authors: VANGURU Raviteja , PASUPULETİ Swetha , MANYAM Ravikanth , ALAPATİ Naga Supriya , AKULA Satya Tejaswi
Published: June 2022

Abstract:
The odontogenic keratocyst be a developmental cyst that's important due to its specific clinical behavior and histopathology. They arise from remnants of the epithelial structures that are related to the event of teeth and occur predominantly intraosseous. However, they occasionally can appear extraosseous in the gingiva as peripheral counterparts. The gingiva is the most common location of peripheral keratocyst, but other sites like mucosal, and intramuscular, epidermal sites have also been reported. The origin of soft tissue OKCs is still under controversy. [1] In this article will be discussing the Oral soft tissue keratocysts reported so far in the literature.
Conclusion:
The clinical evaluation of soft tissue keratocysts is very difficult, they often present different clinical entities, but however, they have to be evaluated histopathologically to be diagnosed as soft tissue keratocyst.
THE ROLE OF STATINS IN PERIODONTAL THERAPY – A REVIEW
Authors: RAJAGOPAL Anjale , ANAND Meena
Published: June 2022

Periodontitis is an inflammatory mechanism causing step by step destruction of the periodontal tissues and alveolar bone. Periodontal treatment is intended to restore the tissues damaged by the disease. Various periodontal procedures have been introduced to lower the destruction; statins are being one among them. They are cholesterol-reducing drugs which have shown to promote bone formation and proven to be effective in periodontal therapy. However, statins have numerous actions, with anti-inflammatory and immunomodulatory effects, as well as the capacity to accelerate new bone formation. The pleiotropic effects of statins have been assessed for their prospective advantage in the therapy of several inflammatory and immune-mediated diseases including periodontitis. Such features could be beneficial for periodontal therapies. This article goes through the history and effects of statins and explores its potential role in periodontal regenerative therapy.