bluuebunny/crossref_metadata_2025 huggingface dataset:
The Recycling of Objective Move in English Research Articles’ Discussion Sections
Authors: Kuhi Davud , Soltani Kimia
Published: September 2022

While numerous studies have scrutinized the rhetorical structures of Research Articles (RAs) through move analysis, it appears that Move Recycling (MR) across RA sections has received little attention. The current study sought to fill this gap by investigating whether the recycling of Objective move (study purposes/questions/hypotheses) in RA Discussion sections, which was previously used in the Introduction, is vulnerable to disciplinary differences. To achieve the study’s objective, 600 English RAs published between 2006 and 2018 in six Soft Science disciplines, with an equal number in each discipline were selected. The move model developed by Weissberg and Buker (1990) served as a road map for analyzing RAs. After identifying the Objective move in RA Introductions, the frequency of its recycling in RA Discussions was calculated and compared across disciplines. The data analysis revealed that disciplinary variations do not result in variations in the recycling of this move in the RA Discussions. It was concluded that the recycling of the Objective move has been established in the sample RA Discussion sections to achieve certain rhetorical functions. The findings may help students, novice researchers, and English for Academic Purposes (EAP) writing instructors understand how Objective move spans in Soft Science RA Discussions.
Mining and analysis of microsatellites in human coronavirus genomes using the in-house built Java pipeline
Authors: Umang  , Bharti P. K. , Husai Akhtar
Published: September 2022

Microsatellites or simple sequence repeats are motifs of 1 to 6 nucleotides in length present in both coding and non-coding regions of DNA. These are found widely distributed in the whole genome of prokaryotes, eukaryotes, bacteria, and viruses and are used as molecular markers in studying DNA variations, gene regulation, genetic diversity and evolutionary studies, etc. However, in vitro microsatellite identification proves to be time-consuming and expensive. Therefore, the present research has been focused on using an in-house built java pipeline to identify, analyse, design primers and find related statistics of perfect and compound microsatellites in the seven complete genome sequences of coronavirus, including the genome of coronavirus disease 2019, where the host is Homo sapiens. Based on search criteria among seven genomic sequences, it was revealed that the total number of perfect simple sequence repeats (SSRs) found to be in the range of 76 to 118 and compound SSRs from 01 to10, thus reflecting the low conversion of perfect simple sequence to compound repeats. Furthermore, the incidence of SSRs was insignificant but positively correlated with genome size (R2 = 0.45, p > 0.05), with simple sequence repeats relative abundance (R2 = 0.18, p > 0.05) and relative density (R2 = 0.23, p > 0.05). Dinucleotide repeats were the most abundant in the coding region of the genome, followed by tri, mono, and tetra. This comparative study would help us understand the evolutionary relationship, genetic diversity, and hypervariability in minimal time and cost.
Two novel mutations in ALDH18A1 and SPG11 gene found by whole-exome sequencing in spastic paraplegia disease patients in Iran
Authors: Komachali Sajad Rafiee , Siahpoosh Zakieh , Salehi Mansoor
Published: September 2022

Hereditary spastic paraplegia is a not common inherited neurological disorder with heterogeneous clinical expressions. ALDH18A1 (located on 10q24.1) gene-related spastic paraplegias (SPG9A and SPG9B) are rare metabolic disorders caused by dominant and recessive mutations that have been found recently. Autosomal recessive hereditary spastic paraplegia is a common and clinical type of familial spastic paraplegia linked to the SPG11 locus (locates on 15q21.1). There are different symptoms of spastic paraplegia, such as muscle atrophy, moderate MR, short stature, balance problem, and lower limb weakness. Our first proband involves a 45 years old man and our second proband involves a 20 years old woman both are affected by spastic paraplegia disease. Genomic DNA was extracted from the peripheral blood of the patients, their parents, and their siblings using a filter-based methodology and quantified and used for molecular analysis and sequencing. Sequencing libraries were generated using Agilent SureSelect Human All ExonV7 kit, and the qualified libraries are fed into NovaSeq 6000 Illumina sequencers. Sanger sequencing was performed by an ABI prism 3730 sequencer. Here, for the first time, we report two cases, the first one which contains likely pathogenic NM_002860: c.475C>T: p.R159X mutation of the ALDH18A1 and the second one has likely pathogenic NM_001160227.2: c.5454dupA: p.Glu1819Argfs Ter11 mutation of the SPG11 gene and also was identified by the whole-exome sequencing and confirmed by Sanger sequencing. Our aim with this study was to confirm that these two novel variants are direct causes of spastic paraplegia.
Melatonin in the Management of Mood and Sleep Problems Induced by Androgen Deprivation Therapy in Prostate Cancer Patients: A Randomized Double-blinded, Placebo-controlled Clinical Trial
Authors: Etedali Alireza , Hosseni Amir Khayam , Derakhshandeh Ali , Mehrzad Valiollah , Sharifi Mehran , Moghaddas Azadeh
Published: September 2022

Background: Androgen deprivation therapy (ADT) has been considered as a mainstay of treatment for advanced prostate cancer. Considering ADT for cancer patients is accompanied with many side effects, such as behavioral and neurologic side effects that adversely affect the quality of life. Objectives: This study aimed to evaluate the effects of melatonin administration on sleep problems and mood changes induced by ADT in prostate cancer patients. Methods: The randomized, double-blind, placebo-controlled trial was designed in the oncology-hematology outpatient clinic of Omid Hospital, Isfahan, Iran. After screening by the hospital anxiety and depression scale (HADS), patients were divided into either an intervention group receiving 6 mg melatonin daily for four weeks or an identical placebo. After that, patients were evaluated by the Pittsburgh sleep quality index (PSQI), the Hamilton Anxiety Rating Scale (HAM-A), and Beck Depression Inventory (BDI) questionnaires at baseline and after 4-week follow-ups. Results: Forty-three patients, including 21 and 22 patients in melatonin and placebo groups, respectively completed follow-ups period. Melatonin administration significantly improved PSQI scores in four domains of sleep quality, sleep latency, sleep efficacy, and daytime dysfunction. After 4-week melatonin supplementation, the severity of depression and anxiety assessed by BDI and HAM-A questionnaires, respectively, decreased non-statistically significant in both melatonin and placebo groups. Conclusions: In our study, melatonin supplementation ameliorated ADT-induced sleep problems in patients with prostate cancers; however, for more conclusive results, further future large and well-designed clinical studies is warranted.
The Loneliest Number
Authors: Feingold Jeffrey ,   After Dinner Conversation
Published: September 2022

Should a bipolar person go on medication if doing so limits their ability to do “great things?” In this work of psychological fiction, Irena is a bipolar piano player that fled, years ago, from an eastern bloc country. Her troubled relationship ended, and her partner died shortly after their breakup. This put her in a deep depression and sent her to therapy for years where she was treated with medication for being bipolar. One day, her dead ex comes to her and tell her she should enter a world renowned piano competition with a $400,000 prize. Her therapist reminds her about her stage fright that ended her career, but Irena insists. She practices, and wins the competition and the money. She decides to move to New York and leaves the $400,000 prize money as a thank you gift to her therapist.
I, Von Economo
Authors: Carter C.F. ,   After Dinner Conversation
Published: September 2022

What would you do to ensure your soul continues forever? Does comfort with death require truth? In this work of philosophical short fiction, the narrator goes to a pseudo-scientist/cult leader who says that by consuming the ashes of the dead, you are consuming their souls and spirit. She is visiting to seek her revenge because her mother and father got wrapped up in the ideology of the man. She tours the facilities, and learns about the “science” and faith behind the process. In the end, she exacts her revenge for what was done to her family.
Before Kant: Universals in German Enlightenment
Authors: Sgarbi Marco ,   Philosophy Documentation Center
Published: September 2022

The paper deals with the problems of universals in German Enlightenment before Kant. The first part reconstructs the sources of the problem of universals, focusing in particular on Leibniz and Locke. The second part examines the early eclectic positions of Brucker, Baumgarten, Hollmann and Crusius. In the fourth part the essay investigates the relation between universals and the various combinatorial projects like those of Ploucquet and Lambert.
The Tacit Dimension of Thomas Aquinas, or Scientia with Michael Polanyi
Authors: Elmore Matthew ,   The Polanyi Society
Published: September 2022

This article explores the common holdings of Thomas Aquinas and Michael Polanyi. More specifically, it suggests that Polanyi’s post-critical philosophy retrieves multiple aspects of the pre-Copernican rationality of Aquinas. First of all, both believe that the faculty of reason is never impartial; it is always committed, driven by the intellect’s appetite for satisfaction. Second, scientific knowledge requires habituation or know-how, which indicates that truth is not rational apart from bodily habitus. Third, reason operates only in a social body, and fourth, science can proceed only by faith in the authority of others. Along these lines, Polanyi relocates the modern scientist in something like a medieval body. Thus, some of Polanyi’s most important ideas are incidental recoveries of the paradigm Aquinas represents.
Smartphone App in Stroke Management: A Narrative Updated Review
Authors: Bonura Adriano , Motolese Francesco , Capone Fioravante , Iaccarino Gianmarco , Alessiani Michele , Ferrante Mario , Calandrelli Rosalinda , Lazzaro Vincenzo Di , Pilato Fabio
Published: September 2022

The spread of smartphones and mobile-Health (m-health) has progressively changed clinical practice, implementing access to medical knowledge and communication between doctors and patients. Dedicated software called Applications (or Apps), assists the practitioners in the various phases of clinical practice, from diagnosis to follow-up and therapy management. The impact of this technology is even more important in diseases such as stroke, which are characterized by a complex management that includes several moments: primary prevention, acute phase management, rehabilitation, and secondary prevention. This review aims to evaluate and summarize the available literature on Apps for the clinical management of stroke. We described their potential and weaknesses, discussing potential room for improvement. Medline databases were interrogated for studies concerning guideline-based decision support Apps for stroke management and other medical scenarios from 2007 (introduction of the first iPhone) until January 2022. We found 551 studies. Forty-three papers were included because they fitted the scope of the review. Based on their purpose, Apps were classified into three groups: primary prevention Apps, acute stroke management Apps, and post-acute stroke Apps. We described the aim of each App and, when available, the results of clinical studies. For acute stroke, several Apps have been designed with the primary purpose of helping communication and sharing of patients’ clinical data among healthcare providers. However, interactive systems Apps aiming to assist clinicians are still lacking, and this field should be developed because it may improve stroke patients’ management.
Logic of the ontological argument
Authors: Jevtić Filip , Vujošević Slobodan
Published: September 2022

In his ontological argument Gödel says nothing about its underlying logic. The argument is modal and at least of second-order and since S5 axiom is used so it is widely accepted that the logic of the argument is the S5 second-order modal logic. However, there is a step in the proof in which Gödel applies the necessitation rule on the assumptions of the argument (see [3]). This is repeated by all of his followers (see [1] and [5]). This application of the necessitation rule can seriously harm the consequence relation of the logic of the ontological argument. It seems that the only way to preserve the modal logic S5 for the ontological argument is to assume some of its axioms in the necessitated form.
Incidence and therapy of relapse after allogenic hematopoietic stem cell transplantation
Authors: Lemajić Nikola , Todorović-Balint Milena , Peulić Nikola
Published: September 2022

Introduction/Aim: Disease relapse after allogeneic hematopoietic stem cell transplantation (allo-HSCT) is one of the most common and most severe post transplantation complications and represents the leading cause of treatment failure and patient death. The aim of this study is to assess the frequency and types of relapse, in relation to the time of occurrence; analyze the influence of conditioning regimens on relapse occurrence; review the therapeutic options after the occurrence of relapse; assess the prognosis in patients with relapse. Methods: This retrospective cohort study included 58 patients who underwent allogeneic hematopoietic stem cell transplantation (allo-HSCT). Pre-transplantation therapy was performed with a reduced-intensity conditioning regimen (RIC) or a myeloablative regimen (MAC). The diagnosis of relapse was made through myelogram analysis, analysis of cytogenetics, analysis of minimal residual disease (MRD), analysis of cellular chimerism, and analysis of immunohematological chimerism of blood group antigens. A database was formed in relation to the examined patient characteristics. Patient survival was analyzed using the Kaplan-Meier method and the log-rang test. Results: MAC (43 patients) was used more frequently than RIC (15 patients), as a conditioning regimen. After transplantation, 18 (34%) out of 53 patients had a relapse. The choice of regimen did not affect the occurrence of relapse, but patients on the RIC regimen lived longer (38.5 ± 7 months) as compared to patients on the MAC regimen (27.8 ± 3.5 months). However, the difference in survival was without statistical significance (p = 0.318). The median survival time of patients who relapsed was 26 ± 5 months, while patients without disease relapse had a median survival time of 41 ± 4 months. Conclusion: Patients who received reduced-intensity regimens (RIC) had a longer survival time, without an increase in the relapse rate. In future, consideration should be given to the inclusion of patients older than 60 years, as candidates for transplantation, as well as to the possible use of prophylactic therapy aimed at preventing relapse in high-risk patients.
Evaluation of calcium hydroxide removal efficiency of different irrigation techniques by microleakage assessment using Computerized Liquid Filtration method
Authors: KUTLU BASMACI Gülsüm , HAZNEDAROĞLU Faruk
Published: September 2022

Aim: To compare the efficiency of sonic irrigation, passive ultrasonic irrigation, and conventional syringe irrigation (CI) in removing pure and injectable calcium hydroxide (CH) from the root canals of mandibular second premolars by measuring the probable microleakage of residual CH particles in root canal obturation using computerized liquid filtration (CLF).
Materials and Methods: Eighty instrumented mandibular second premolars were categorized into three experimental groups (n = 20 each) based on the irrigation method used for removing CH and a control group (n = 20) in which CH was not used. Each experimental group was divided into two equal groups (pure and injectable CH). After 1 week, CH was removed from the root canals, and the teeth were obturated. CLF measurements were performed 1 week after obturation. Nonparametric variables between two groups were compared using the Mann-Whitney U test, and the Kruskal-Wallis test was used to compare more than two groups. The significance level was set at p < 0.05.
Results: All experimental groups showed higher leakage values than the control group. The highest leakage values were evident in the CI group, and the lowest leakage values were found in the sonic (EDDY) irrigation group. No significant differences were detected among the different forms of CH.
Conclusions: None of the analyzed techniques could completely remove CH from root canals, resulting in higher leakage values. Sonic irrigation with EDDY was the best in removing CH from root canals.
Effects of Continuous Positive Airway Pressure (CPAP) Ventilation During Cardiopulmonary Bypass on Postoperative Outcomes
Authors: POLAT Vural , ADA Fatih
Published: September 2022

Objective: In this study, the relationship between the duration of intensive care unit stay, hospital stay, and intubation times between nonventilated and continuously ventilated groups of patients who underwent surgery with a cardiopulmonary bypass (CPB) device was investigated.

Methods: In the study, we divided patients into two groups. Continuously ventilated during CPB group and non-ventilated group. In the continuously ventilated group, respiratory rate was 6 per minute, tidal volume was 6 ml/kg and FiO2 was 50%. In the non-ventilated group, the lungs were completely removed from the ventilator after the cross-clamp was placed.

Results: Although the duration of intensive care unit stays, length of hospital stay, and intubation times were relatively short in the continuously ventilated group, there was no statistically significant difference between the two groups.

Conclusion: There is a need for new studies on continuous ventilation during CPB to be designed based on subgroups and larger volumes.
Akaryakıt İstasyonları Özelinde Toprak Kirliliğinin Kontrolü ve Noktasal Kaynaklı Kirlenmiş Sahalara Dair Yönetmelik’in Aşamaları ve Uygulamaları
Authors: GÖKYAY Orhan , KARA Gökberk
Published: September 2022

Sanayinin gelişmesi, nüfusun artması, şehirleşme gereksinimi sonucunda daha çok enerjinin ve kimyasal maddenin tüketim ve kullanımının bir sonucu olarak akaryakıt istasyonlarının sayısı 1990’lı yıllara göre artan bir ivme göstermiştir. Enerji Piyasası Denetleme Kurulu (EPDK) 2022 verilerine göre Türkiye genelinde yaklaşık on üç bin lisanslı aktif akaryakıt istasyonu olduğu ve bu istasyonların faaliyetleri gereği yeraltı akaryakıt tanklarında sürekli olarak binlerce litre akaryakıt ürünleri barındırdıkları bilinmektedir. Akaryakıt istasyonlarının birçoğunun mücavir alan sınırları içerisinde olması, mevcut yeraltı akaryakıt tanklarının yaşlarının 10, hatta 20 yıl üzerinde olması, yeraltı ve yerüstü kaynaklarına yakın mesafede kurulmuş olmaları, gaz detektörü olmayan bodrum katlarının olması, yakıt istasyonlarında olası parlama, patlama, sızıntı gibi nedenlerle toprak ve yeraltı suyu kirliliği başta olmak üzere, çevre ve halk sağlığı açısından birçok potansiyel riski de beraberinde oluşturmaktadır. Bu çalışmanın amacı, 8.6.2010’de yayımlana ve 237 adet sektörü ve binlerce tesisi kapsayan Toprak Kirliliğinin Kontrolü ve Noktasal Kaynaklı Kirlenmiş Sahalara Dair Yönetmelik (TKKNKKSDY)’in, faaliyetleri sebebiyle binlerce litre petrol ve türevi kimyasal barındıran akaryakıt istasyonlarının özelinde incelenmesi ve buralarda olası toprak ve yeraltı suyu kirliliğinde çevre ve halk sağlığı açısından TKKNKKSDY aşamalarının ortaya konmasıdır. Bu şekilde yaşanan zorlukları azalacağına ve olası kafa karışıklıklarını giderileceğine inanılmaktadır.
Banking, Competitiveness and Sustainability: The Perspective of the Three Global Actors: US, China, Europe
Authors: Istudor Nicolae , Nitescu Dan Costin , Dumitru Valentin Florentin , Anghel Cristian
Published: September 2022

The research presents the interrelationships between banking performance, competitiveness and sustainability of the three banking systems and the impact of each sustainability variable selected on the other macroeconomic indicators in short, medium and long-time horizon. The empirical study involved the use of a panel Auto Regressive Vector methodology and was based on macroeconomic indicators relevant to the performance of the banking system (return on assets, return on equity, an annual growth rate of Gross Domestic Product), as well as indicators that can be assimilated to sustainability (renewable fuels used, CO2 emissions). The dependent variables were return on assets and the annual growth rate of Gross Domestic Product. The global sample analyzed comprises 29 countries, spread over three continents (Europe, North America, Asia), with data collected over a 10-years period (2011-2020). These countries together account for approximately 62% of global GDP (data from 2020). The research results show that as banks invest in green energy and sustainable products, competitiveness will also increase, which will have a negative impact on profitability in the short term. In the medium and long term, this impact will become positive also in terms of profitability increase. This strategic move to develop sustainable business models and to finance a higher percentage of green investments also adds extra competitive advantages, such as reputation and smart differentiation, from other less sustainability-oriented banking systems. The process impacts the systemic level, the macro perspective, the banking organizational level, the micro perspective, together with the perception of the customers.
The Hazard Model for European SMEs: Combining Accounting and Macroeconomic Variables
Authors: Karas Michal
Published: September 2022

Predicting the default of small and medium-sized businesses (SMEs) using the hazard model approach represents an area relatively neglected by mainstream literature. On the one hand, SMEs are regarded as the backbone of the economy; on the other hand, their specific features pose a challenge to the modelling process. This issue is further complicated by the fact that many modern structural approaches to default modelling are simply unsuitable for SMEs due to their limited size. Therefore, researchers only rely on accounting, non-financial, or macroeconomic data. The gap is especially noticeable in several studies on SME default prediction that employ the hazard model approach, which models the probability of default with respect to the time factor. A better understanding of the factors driving SMEs’ default might help in adopting policies that strengthen their competitiveness. The aim of this study is to introduce a hazard model for EU-28 SMEs and analyse the contribution of macroeconomic indicators and proxies of external financial obstacle factors. This model was derived using the Cox semiparametric proportional model, leaving the baseline hazard unspecified and employing macroeconomic variables as explanatory variables. By analysing a sample of 202,209 European SMEs over the period 2014–2019, the results indicated that factors of employment rate, personal cost per employee, and interest rate play significant roles in determining the survival of SMEs. Adding these macroeconomic variables significantly increased the area under curve values compared to the situation where only accounting variables were used.
Evaluating Competitiveness in the Supply Chain Management of Small and Medium Scale Enterprises
Authors: Muangmee Chaiyawit , Kassakorn Nuttapon , Khalid Bilal , Bacik Radovan , Kot Sebastian
Published: September 2022

This research investigated Supply Chain Management (SCM) in Small and Medium Enterprises (SMEs) in Thailand, Slovakia, and Poland and compared the SCM practices among the three countries. The sole purpose was to first determine the various factors that influence SCM operations and SCM practices in each of the countries and then find out whether there is a difference among the three countries in terms of SCM operations and practices. The study was conducted using primary data collected from SME management personnel from the three countries. A structured questionnaire was used to collect the data using a 5-point Likert scale. The data was analyzed using multi-group Structural Equation Modeling (SEM). The results of the study indicated that supply chain management practices and operations adopted by the small and medium enterprises in Thailand, Slovakia, and Poland were invariant. The environmental sustainability elements in SCM and the social aspects of sustainability in SCM have positively influenced SCM practices in all countries. The study recommended that SMEs in the countries should consider adopting the factors that support SCM, operationalizing the SCM through enhancing the capabilities of the end-user, and vitally taking into consideration the environmental sustainability elements in SCM, such as environmentally-friendly production processes, taking action towards waste management, and adopting production processes that inhibit the emission of harmful substances into the atmosphere by encouraging the implementation of policies that foster the use of renewable energy sources in production.
Classes and Boundary Properties of Functions in the Open Unit Disk
Authors: Hristov Miroslav
Published: September 2022

Let \(\psi\) be a Blaschke product and \(d\theta(\mathop{\rm supp}\psi)=0\). In this paper we prove that the functions of Bourgain algebra \( (\psi H^\infty (D), L^\infty (D))_b \) have essential non-tangential limit at almost every point of \(T=\{z:\mid z\mid = 1\}\).
Genetic Diversity Assessment of Calendula officinalis Wilding Plants Locally Grown in Bulgaria, Using SRAP Markers
Authors: Zagorcheva Tzvetelina , Rusanova Mila , Rusanov Krasimir , Atanassov Ivan
Published: September 2022

The pot marigold (Calendula officinalis L.) is a well-known garden plant cultivated also for medicinal purposes. In Bulgaria, C. officinalis is an annual plant, often self-seeding and generating garden escapees. The present study describes assessment of the genetic diversity of wilding C. officinalis plants originating from the region of the Rose Valley, Bulgaria, using SRAP (sequence-related amplified polymorphism) markers. Analysis of the data using the Structure software did not support the existence of a clear genetic structure within this set of analyzed wilding plants. Further comparative SRAP analysis of small sets of C. officinalis plants originating from seeds of wilding plants and seeds derived from various European seed suppliers was carried out. The results suggest that the genetic diversity of the tested wilding plants largely resembles the range of genetic diversity of the plant sets derived from commercially available C. officinalis seeds. The possibility of using wilding C. officinalis plants for selection of breeding lines and varieties, well adapted to the local conditions and suitable for organic growing and production of bioactive extracts and compounds is discussed.
Device for Semiconductor Carrier Mobility Measurement
Authors: Lozanova Siya , Ralchev Martin , Roumenin Chavdar
Published: September 2022

A novel method and a device measuring the mobility of majority carriers in semiconductors using the Hall current is proposed and experimentally tested. The geometry of the mobility-determining structures is similar to the topology of the so-called Corbino disk. The semiconductor wafer, in our case, n-silicon, has circular form and two concentric ohmic contacts: one of them in the central zone of the disk, and the other around the circumference. In contrast to this well-known Corbino configuration, the peripheral electrode is interrupted, whereas the size of the so-formed arc is many times smaller than the remaining section of the external perimeter. The two ohmic contacts are brought together to a current source, and the external magnetic field is applied perpendicularly to the disk plane. The ends of the interrupted electrode are connected to an electronic galvanometer measuring the Hall current involved in the Corbino structure. The experiments were carried out at room temperature and in liquid nitrogen. The results obtained with the new device are comparable to the previously known mobility values.
Organic Molecular Markers in a Fluvisol Amended with Organic Ameliorants
Authors: Harizanova Milena , Atanassova Irena , Benkova Maya , Nenova Lyuba , Simeonova Tsetska
Published: September 2022

Three types of organic ameliorants, sheep manure, sewage sludge from a waste water treatment plant and a plant compost were added to an Alluvialmeadow soil (Fluvisol). There was evidence for well-preserved biomarker signals and higher values of the carbon preference index (CPI) in the sludge and manure-treated soils, while lower values, typical of microbial alkanes, indicating a high degree of degradation were observed in the plant compost amended soil. Sludge and sheep manure originating metabolic products, such as steroids and polycyclic aromatic hydrocarbons (PAHs) have been preserved in the Fluvisol after 104 days of composting.
Migration of government records from on-premises to cloud computing storage in South Africa
Authors: Shibambu Amos
Published: September 2022

The purpose of this study was to investigate the public sector's willingness to entrust their records to cloud computing technology with the view to propose potential strategies to encourage cloud migration. This qualitative study, utilised interviews, and document analysis to collect data. The target population consisted of purposively chosen chief information officers and records practitioners from the national government departments in South Africa. A total of ten participants were interviewed and data were analysed thematically. The study made several findings such as that the government was hesitant to subscribe to the privately-owned cloud due to security concerns such as attack of a physical host, bankruptcy, cross-border jurisdiction, sovereignty, access to information, and data loss, as well as the absence of legislation on cloud storage. The study recommends for the enactment of cloud storage legislation and encourage the storage of digital records on a cloud within the borders of South African virtual space.
Irradiation with carbon ion beams affects soybean nutritional quality in early generations
Authors: Liu Changkai , Wang Xue , Li Yansheng , Chen Heng , Zhang Qiuying , Liu Xiaobing
Published: September 2022

As people’s demand for healthy diet increases, improving soybean seed nutritional quality is becoming as important as yield. Carbon ion beam radiation (CIBR) is an effective method to create soybean mutants, and thus breeding cultivars with better seed nutritional quality. In this study, the high-yield soybean line ‘Dongsheng 28’ was used, and three CIBR doses (100, 120, and 140 Gy) were used to explore the characteristics of quality separation and variation in the offspring of early mutant populations. Eleven quality traits, including protein, oil, sucrose, soluble sugar, iron (Fe), manganese (Mn), zinc (Zn), cupper (Cu), daidzin, glycitin, and genistin concentrations were analyzed in the M2 and M3 generations. The results revealed that the range of protein and oil concentration of all three CIBR doses changed by 38.5–42.9% and 18.8–23.8% in the M2 and M3 generations, respectively, while soluble sugar and sucrose concentrations changed by 48.1–123.4 and 22.7–74.7 mg/g, with significant effects by 140 Gy across the two generations. Therefore, around the optimum range, a higher CIBR dose is better for high protein, oil, and sugar varieties selection. In general, irradiation raised isoflavone concentrations, but 140 Gy had an inhibitory effect on isoflavone concentrations in the M3 generation. Although a variety could not be released in the M2 or M3 generation, the results of this study have important guiding significance for the targeted cultivation of specific nutritional quality materials. For instance, a lower irradiation dose is preferable when breeding targets are higher isoflavones and Mn concentrations. It is essential to increase the irradiation dose if the breeding targets contain high levels of protein, oil, sucrose, soluble sugars, Fe, Zn, and Cu.
Progressive overload without progressing load? The effects of load or repetition progression on muscular adaptations
Authors: Plotkin Daniel , Coleman Max , Van Every Derrick , Maldonado Jaime , Oberlin Douglas , Israetel Michael , Feather Jared , Alto Andrew , Vigotsky Andrew D. , Schoenfeld Brad J.
Published: September 2022

Background

Progressive overload is a principle of resistance training exercise program design that typically relies on increasing load to increase neuromuscular demand to facilitate further adaptations. However, little attention has been given to another way of increasing demand—increasing the number of repetitions.

Objective

This study aimed to compare the effects of two resistance training programs: (1) increasing load while keeping repetition range constant vs (2) increasing repetitions while keeping load constant. We aimed to compare the effects of these programs on lower body muscle hypertrophy, muscle strength, and muscle endurance in resistance-trained individuals over an 8-week study period.

Methods

Forty-three participants with at least 1 year of consistent lower body resistance training experience were randomly assigned to one of two experimental, parallel groups: A group that aimed to increase load while keeping repetitions constant (LOAD: n = 22; 13 men, nine women) or a group that aimed to increase repetitions while keeping load constant (REPS: n = 21; 14 men, seven women). Subjects performed four sets of four lower body exercises (back squat, leg extension, straight-leg calf raise, and seated calf raise) twice per week. We assessed one repetition maximum (1RM) in the Smith machine squat, muscular endurance in the leg extension, countermovement jump height, and muscle thickness along the quadriceps and calf muscles. Between-group effects were estimated using analyses of covariance, adjusted for pre-intervention scores and sex.

Results

Rectus femoris growth modestly favored REPS (adjusted effect estimate (CI90%), sum of sites: 2.8 mm [−0.5, 5.8]). Alternatively, dynamic strength increases slightly favored LOAD (2.0 kg [−2.4, 7.8]), with differences of questionable practical significance. No other notable between-group differences were found across outcomes (muscle thicknesses, <1 mm; endurance, <1%; countermovement jump, 0.1 cm; body fat, <1%; leg segmental lean mass, 0.1 kg), with narrow CIs for most outcomes.

Conclusion

Both progressions of repetitions and load appear to be viable strategies for enhancing muscular adaptations over an 8-week training cycle, which provides trainers and trainees with another promising approach to programming resistance training.
Gestión local de la información en biodiversidad: fomentando la ciencia participativa en el sur de Chile
Authors: Sánchez-Jardón Laura , Uribe-Paredes Roberto , Álvarez-Saravia Diego , Aldea Cristian , Raimilla Víctor , Velázquez Eduardo , Millán Susana , Águila Julio
Published: September 2022

Gestión local de la información en biodiversidad: fomentando la ciencia participativa en el sur de Chile. La caracterización, la cuantificación y el seguimiento de la biodiversidad han sido algunos de los principales retos de la conservación. El Sistema de Información en Biodiversidad para Aysén (SIB-Aysén) es una plataforma colaborativa e interactiva para la consulta y gestión de datos biológicos que actualmente contiene más de 10 000 registros de unas 2800 especies de plantas, animales, hongos y microalgas presentes en la región subantártica de Aysén, Chile. Para construir la base de datos, se recopilaron los registros publicados en revistas especializadas, publicaciones divulgativas y documentos técnicos validados por la comunidad científica y se sistematizaron de acuerdo al estándar Darwin Core. En la plataforma, construida usando herramientas de libre acceso, para cada especie se muestra una ficha con descripción general, galería de fotografías y registros geolocalizados. Se encuentra disponible para todo público en internet a través del enlace https://kataix.umag.cl/sib-aysen. Se dispone de un módulo para la participación ciudadana que permite a las comunidades locales ingresar sus propios registros participativos, los cuales deben ser validados por especialistas. El proceso participativo se ha desarrollado mediante diversas iniciativas de innovación social como Hongusto y el Laboratorio Abierto de Ciencias Subantárticas, en los que se han involucrado científicos y comunidades locales. En este artículo se presenta el proceso de generación de este sistema para ampliar el conocimiento y valoración de la biodiversidad local.
Attenuation of Potassium Bromate-induced Infertility by African Locust Bean (Parkia biglobosa) Seed
Authors: Ezirim E. O. , Onyeaghala C. A. , Orji S. F. , Ugwu C. N. , Igwenyi C. , Uche C. L. , Abali I. O. , Onyekachi O. I. N. , Nwobodo M. U. , Agu F. U. , Iwuoha C. E. , Chika-Igwenyi N. M. , Airaodion A. I.
Published: September 2022

Background: Parkia biglobosa seed has been reported to enhance sperm quality. Thus, this study sought to assess its ability in attenuating KBrO3-induced sperm abnormalities.

Methodology: P. biglobosa was extracted with soxhlet extractor with 95% ethanol as the solvent. Twenty-four adult male Wistar rats were acclimatized under laboratory conditions and were randomly grouped into A, B, C and D. Group A was given distilled water orally. Animals in groups B, C and D were administered 100 mg/kg body weight of potassium bromate, but groups C and D were also treated with 100 and 200 mg/kg body weight of P. biglobosa respectively. Both potassium bromate and P. biglobosa were freshly prepared on daily basis and administered to rats by oral gavage. After 28 days of treatment, the animals were sacrificed under mild diethyl ether anaesthetization 24 hours after cessation of the last treatment. The cauda epididymis were separated from both testes and tinged with 2 mL of normal saline then teased. The suspension was mixed through a metallic net to avoid any other tissue contamination. This suspension was used for the determination of the sperm parameters.

Results: Exposure of animals to 100 mg/kg body weight of KBrO3 significantly reduced sperm count, sperm motility, sperm viability and seminal pH but elevated sperm morphology when compared with animals in the control group at p<0.05. These perturbations were attenuated by 100 and 200 mg/kg body weight of P. biglobosa seed extract in a dose-dependent manner.

Conclusion: The result of this study showed that potassium bromate induced abnormalities in sperm cells of treated animals, and seed extract of P. biglobosa attenuated these abnormalities in a dose-dependent manner. This pharmacological study is a useful tool for further drug development from the natural plant products.
Development and Experimental Investigation of Briquetting Machine for Use in Rural Area
Authors: Ramani Maulik , Savaliya Lalit , Chauhan P. M.
Published: September 2022

Biomass is an organic matter such as agricultural crop residues, forest plant materials and animal wastes used as animal fodder, domestic fuel energy source in India. The briquetting technology is the extrusion process of various biomass materials to produce briquettes as a biofuel substitute for fuel wood, coal and charcoal. Mahua (Madhuca Indica) seeds oil extraction plant have waste known as mahua deoiled cake (Doc) is major forest biomass and is locally available in southern parts of Gujarat. The development of an efficient and low-cost screw press type briquetting machine appropriate for rural peoples of developing countries was carried out. The four combinations with different proportions of raw biomass such as mahua seed deoiled cake, coal, rice husk and grass were used to produce briquette C1 (70:10:10:10), C2 (50:20:20:10), C3 (100:0:0:0), and C4 (50:0:50:0), respectively. The properties of briquettes were determined as the density of briquettes, shatter resistance, tumbling resistance, water retention test and calorific value. The highest resistance to water penetration was observed for combination C1 briquettes as 52.20% because mahua Doc has less porosity and high density. Combination C4 briquettes were observed for a maximum degree of densification and maximum energy density ratio as 31.37% and 1.1, respectively. Tumbler resistance and shatter resistance were observed maximum for combination C1 as 86.70% and 99.82%, respectively which comprises 70% mahua Doc, 10%, coal, 10% rice husk and 10% grass. A high calorific value was found 3946.43 kcal/kg in combination C3 (100:0:0:0) because briquette made of 100% mahua Doc. The addition of Mahua Doc matter in the briquette was found better results as an increase in calorific value, water retention, shatter and tumbling resistance.
Eminent Roles of Micro-nutrients in Quality Seed Production
Authors: Mukherjee Aritra , Bordolui Sanjoy Kumar
Published: September 2022

There are seventeen vital nutrients required for plant growth and development.  Out of these essential nutrients the elements needed in trace amounts are known as micro-nutrients. Seed priming and treatment with micronutrients has the potential to meet crop micronutrient demand and improve seedling emergence and stand establishment, grain micronutrient enrichment and yield.  Micronutrients may be applied to the soil, foliar sprayed or added as seed treatments or seed priming. While the essential amounts of micronutrients can be provided by any of these methods, foliar sprays have been more successful in yield improvement and seed quality enrichment. Due to high cost has limited its wider adjustment, particularly by wealth poor farmers. Micronutrients may be applied either by coating with micronutrients or by soaking in nutrient solution of a specific concentration for a specific duration (seed priming). The potential micronutrients for seed treatments are Zinc (Zn), Boron (B), Molybdenum (Mo), Manganese (Mn), Copper (Cu) and Cobalt (Co) for improving growth, development, yield and seed quality enrichment. Treated or primed seeds generally have better, faster and more integrated germination. Micronutrient application in seed can also be done through seed coating and pelleting. Seed priming or seed coating seems reasonable, inexpensive and an easy method of micronutrient delivery mostly by small land holders in developing countries.
KNOWLEDGE MANAGEMENT FOR QUALITY ASSURANCE INNOVATION IN THE OPERATIONS QUALITY ASSURANCE DIVISION OF BANK BAKTI KARYA PURNA
Authors: Joko Patritius , Tjakraatmadja Jann Hidajat
Published: September 2022

Bank Bakti Karya Purna was a pseudonym for a real bank in Indonesia. As the bank continued to expand, the operational function needs to enhance its capability to keep up. Accordingly, the Operations Quality Assurance division (Ops QA) was expected to innovate to redefine its role, whereby, in addition to its traditional role as Inspector, the organization has to assume two other roles of Guardian and Preventive Control Agent. This research was intended to assist Ops QA to meet management expectations. To overcome the knowledge and capability gaps discovered, this research proposed a knowledge management solution that provides actionable items within three knowledge management components of people, process, and technology to enable the innovation to achieve the Ops QA objectives.
Consensus-Based Recommendations on Priority Activities to Address Acute Kidney Injury in Children
Authors: Goldstein Stuart L. , Akcan-Arikan Ayse , Alobaidi Rashid , Askenazi David J. , Bagshaw Sean M. , Barhight Matthew , Barreto Erin , Bayrakci Benan , Bignall Orville N.R. , Bjornstad Erica , Brophy Patrick D. , Chanchlani Rahul , Charlton Jennifer R. , Conroy Andrea L. , Deep Akash , Devarajan Prasad , Dolan Kristin , Fuhrman Dana Y. , Gist Katja M. , Gorga Stephen M. , Greenberg Jason H. , Hasson Denise , Ulrich Emma Heydari , Iyengar Arpana , Jetton Jennifer G. , Krawczeski Catherine , Meigs Leslie , Menon Shina , Morgan Jolyn , Morgan Catherine J. , Mottes Theresa , Neumayr Tara M. , Ricci Zaccaria , Selewski David , Soranno Danielle E. , Starr Michelle , Stanski Natalja L. , Sutherland Scott M. , Symons Jordan , Tavares Marcelo S. , Vega Molly Wong , Zappitelli Michael , Ronco Claudio , Mehta Ravindra L. , Kellum John , Ostermann Marlies , Basu Rajit K. ,   Pediatric ADQI Collaborative
Published: September 2022

Importance

Increasing evidence indicates that acute kidney injury (AKI) occurs frequently in children and young adults and is associated with poor short-term and long-term outcomes. Guidance is required to focus efforts related to expansion of pediatric AKI knowledge.

Objective

To develop expert-driven pediatric specific recommendations on needed AKI research, education, practice, and advocacy.

Evidence Review

At the 26th Acute Disease Quality Initiative meeting conducted in November 2021 by 47 multiprofessional international experts in general pediatrics, nephrology, and critical care, the panel focused on 6 areas: (1) epidemiology; (2) diagnostics; (3) fluid overload; (4) kidney support therapies; (5) biology, pharmacology, and nutrition; and (6) education and advocacy. An objective scientific review and distillation of literature through September 2021 was performed of (1) epidemiology, (2) risk assessment and diagnosis, (3) fluid assessment, (4) kidney support and extracorporeal therapies, (5) pathobiology, nutrition, and pharmacology, and (6) education and advocacy. Using an established modified Delphi process based on existing data, workgroups derived consensus statements with recommendations.

Findings

The meeting developed 12 consensus statements and 29 research recommendations. Principal suggestions were to address gaps of knowledge by including data from varying socioeconomic groups, broadening definition of AKI phenotypes, adjudicating fluid balance by disease severity, integrating biopathology of child growth and development, and partnering with families and communities in AKI advocacy.

Conclusions and Relevance

Existing evidence across observational study supports further efforts to increase knowledge related to AKI in childhood. Significant gaps of knowledge may be addressed by focused efforts.
Eligibility for Lung Cancer Screening Among Women Receiving Screening for Breast Cancer
Authors: Titan Ashley L. , Baiu Ioana , Liou Doug , Lui Natalie S. , Berry Mark , Shrager Joseph , Backhus Leah
Published: September 2022

Blurb: This cohort study assesses the number of women who were eligible for and underwent lung cancer screening among those who received mammograms at a single academic medical center.
Hospital Occupancy and Emergency Department Boarding During the COVID-19 Pandemic
Authors: Janke Alexander T. , Melnick Edward R. , Venkatesh Arjun K.
Published: September 2022

This cross-sectional study uses national benchmarking data to evaluate hospital occupancy and emergency department boarding during the COVID-19 pandemic.