bluuebunny/crossref_metadata_2025 huggingface dataset:
Using Objectives and Key Results (OKRs) and Slack: A Case Study of Coordination in Large-Scale Distributed Agile
Authors: Stray Viktoria , Moe Nils Brede , Vedal Henrik , Berntzen Marthe
Published: November 2021

Today, many large-scale software projects have members working from home, which has changed the way teams coordinate work. To better understand coordination in this setting, we conducted a case study through which we examined two teams in a large-scale agile project by observing meetings and conducting 17 interviews. Through the lens of Relational Coordination Theory (RCT), we analyzed the use of the goal-setting framework Objectives and Key Results (OKRs) and the collaboration tool Slack. Slack was used for frequent, timely, and problem-solving communication and, and its use decreased the number of planned meetings. However, discussions often started on Slack and continued in virtual ad-hoc meetings. The use of OKRs facilitated knowledge sharing, helped the teams align their goals, and provided inter-team insights. The main implication of our research is that projects using OKRs need to support project members, especially in formulating the key results that align and motivate the teams to work toward the same mission.
Stochastic Optimization of Microgrid Operation With Renewable Generation and Energy Storage
Authors: Aaslid Per , Korpås Magnus , Belsnes Michael M , Fosso Olav Bjarte
Published: November 2021

The operation of electric energy storages (EES) in power systems where variable renewable energy sources (VRES) and EES must contribute to securing the supply can be considered as an arbitrage against scarcity. The value of using stored energy instantly must be balanced against its potential future value and future risk of scarcity. This paper proposes a multi-stage stochastic programming model for the operation of microgrids with VRES, EES and thermal generation that is divided into a short- and a long-term model. The short-term model utilizes information from forecasts updated every six hours, while the long-term model considers the value of stored energy beyond the forecast horizon. The model is solved using stochastic dual dynamic programming and Markov chains, and the results show that the significance of accounting for short- and long-term uncertainty increases for systems with a high degree of variable renewable generation and EES and decreasing dispatchable generation capacity.
Effect of land-use on particulate organic carbon and carbohydrates distributions in dry- and wet- sieved stable aggregates in an ultisol
Authors: B.E. Udom , U.G. Simon
Published: November 2021

Particulate organic carbon (POC) and carbohydrates (R-CHO) disytibutions in dry- and wet-sieved aggregates in four land-use types in southern Nigeria were studied. The land-use types were: secondary forest, 5-year fallow plots, cocoa plantation, and 5-year continuous cultivation. The results showed that, land types affected soil organic carbon fractions, soil organic carbon density, bulk density, and aggregate stability. Soil aggregation following 5-year continuous cropping increased the soil bulk density. POC and R-CHO in 4.75-2.0 mm dry-sieved ag- gregates in forested and 5-year fallow soils were 12.7 and 5.3 g kg-1, respectively. This is compared to 8.9 and 4.1 g kg-1 in cocoa plantation and 8.0 and 4.9 g kg-1, respectively, in 5-year cropping. There was a significant positive correlation be- tween R-CHO and Ksat (r = 0.811), and non-significant correlation between R- CHO and MWD. (r = 0.573). A positive correlation was also established between POC and MWD (r = 0.764). The results also indicated that POC, rather than R- CHO, was more responsible for maintaining the macro-aggregate stability in for- ested and 5-year fallow soils. Wetting of the soil aggregates in water results in significant losses of POC and R-CHO in 5-year continuous cropping.
PENYULUHAN PEMBERIAN BABY MASSAGE DALAM MENINGKATKAN KUALITAS TIDUR BAYI USIA 11 - 25 BULAN DI POSYANDU HARAPAN BUNDA
Authors: Ningrum Eka Widya , Pristianto Arif
Published: November 2021

Tidur merupakan salah satu kebutuhan yang sangat penting bagi bayi, karena kualitas tidur yang baik membantu proses pertumbuhan dan perkembangan yang optimal. Salah satu cara yang digunakan untuk memperbaiki kualitas tidur bayi dengan pemberian baby massage. Teknik baby massage adalah memberikan sentuhan lembut pada kulit bayi agar merangsang peredaran darah dan menambah energi gelombang oksigen yang lebih banyak ke otak sehingga memacu sitem sirkulasi dan respirasi yang lebih baik. Rasa rileks dan nyaman akibat sentuhan massage mampu meningkatkan kualitas tidur bayi, meningkatkan imunitas atau kekebalan tubuh serta meningkatkan berat badan bayi. Tujuan program penyuluhan ini untuk mengetahui manfaat baby massage dalam meningkatkan kualitas tidur bayi usia 11 - 25 bulan.  Metode kegiatan penyuluhan dengan memberikan edukasi di posyandu harapan bunda dan melakukan kunjungan ke rumah para ibu untuk pemberian baby massage serta membagikan kuisioner. Hasil kegiatan penyuluhan ini didapatkan tingkat pengetahuan pengetahuan para ibu tentang peran fisioterapi dan manfaat baby massage dalam kategori kurang dengan persentase 59% serta kualitas tidur pada balita rata – rata dalam kategori baik dengan persentase 73%. Simpulan dari kegiatan penyuluhan ini bahwa pemberian baby massage mampu meningkatkan kualitas tidur bayi usia 11 - 25 bulan.
Prevention of post-surgical Complications following Odontectomy in patients with Underlying Diabetes mellitus
Authors: Kanishyna Тetiana М. , Shkilniak Liudmila I.
Published: November 2021

Aim: Purpose of the study. The study was dedicated to assessment of the effect of photon physiotherapeutic therapy combined with the use of PRF clot on the course of regeneration processes in a socket of extracted tooth in DM patients.
materials and methods: Thirty patients with confirmed diabetes mellitus aged 40 - 60 referred to the Pirogov Memorial Clinical Hospital (Vinnytsia) that required tooth extraction were engaged in the study. Patients were assigned into two groups: Group I patients with spontaneously healed post-extraction wounds, and Group II patients subjected to physiotherapy in combination with the PRF. The physiotherapeutic effect was achieved by using a multispectral photon physiological system. Platelet-rich fibrin (PRF) was produced immediately before tooth extraction from the patients` venous blood. The efficacy of the photon physiotherapeutic therapy combined with the use of PRF clot was studied by the morphological methods.
Results: The study of pathomorphological features of the post-extraction wound regeneration revealed differences in patients of Groups I and II. In Group II patients, the treatment was characterized by an anti-inflammatory effect (less abundant inflammatory infiltrate with fewer polymorphonuclear leukocytes in bioptic samples), accelerated regeneration process, as evidenced by a larger number of fibroblasts on Day 3 and Day 7 of follow-up, and faster development of fibrous structures in the granular tissue. Group II patients demonstrated earlier post-extraction wound epithelialization and more active angiogenesis.
Conclusions: The study of pathomorphological features of post-extraction wound regeneration proved the therapeutic efficacy of the photon effect combined with the transport of PRF to the extracted tooth socket in two DM patient groups (Group I patients with spontaneously-healed post-extraction wounds, and Group II patients subjected to physiotherapy in combination with PRF).
Prevention of Complications of Removal of the mandibular Third molars
Authors: Tkachenko Pavlo I. , Hohol Andrii M. , Pankevych Artur I. , Kolisnyk Inna A. , Bilokon Serhii O. , Lokhmatova Nataliia M. , Popelo Yuliia V.
Published: November 2021

Aim: Study of the causes that may contribute to complications during and after tooth extraction to justify treatment and prevention measures.
materials and methods: A retrospective analysis of the content of ambulatory cards and protocols of operations of 168 patients for the period from 2016 to 2018 and evaluation of the results of personal work for 2018-2020 related to surgical interventions in 134 patients which removed the third lower molars.
Results: According to the retrospective material, damage to the inferior alveolar nerve was found in 5.9% of cases, lingual nerve – in 3.3% of cases, the prevalence of alveolitis with simple removal was 16.3% of cases, at difficult and surgical removal – 3.9% of cases. The application of our proposed treatment and prevention complex allowed to reduce their rates to 3.1%, 2.3%, 8.0% and 3.8% of cases, respectively. Risk factors for complications have been identified.
Conclusions: when planning the method of surgical removal of third lower molars it is necessary to take into account the probability of its intimate location in relation to inferior alveolar nerve and lingual nerve. The presence of focus of destruction with signs of acute or exacerbation of chronic inflammation in the periodontal bone tissue of the causative tooth is a risk factor for alveolitis and an indication for the appointment of treatment and prevention in the preoperative period, even with simple removal.
Bruxism as a marker of Violation of psychological Adaptation in Computer game players
Authors: Sidorova Alla I. , Lyashenko Lila I. , Pavlenkova Elena V. , Pavlenkо Svetlana A. , Lobach Larysa M.
Published: November 2021

Aim: To study the relationship between the psycho-emotional state of computer game players with the development of bruxism, its early diagnosis in people at risk, increasing the effectiveness of preventive measures in people with this pathology.
materials and methods: At the first stage of the study, a survey of 120 people (85 - men, 35 - women) aged 18 - 30 years was conducted. The computer club was chosen as the place of the poll. The questionnaire is represented by questions that were aimed at identifying clinical manifestations of bruxism. Also, the subjects were asked to take an automated FPI test to assess the psycho-emotional state. In the second stage of the study, according to the results, the main group of patients with bruxism was identified. It consisted of 68 people aged 18-30 years (50 – men, 18 – women). The control group of people consisted of 20 volunteers (10 – women, 10 – men), who did not show clinical manifestations of bruxism and temporomandibular joint dysfunction and who do not play computer games.
Results: According to a survey of 120 people aged 19-29, who often play computer games, it was found that 48.33% had bruxism. In 96.55% of the analysis of the FPI test revealed signs of mental distress. In the control group, the results of FPI in most indicators were average.
Conclusions: The prevalence of bruxism among young people who play computer games was 48.33%, which is associated with psycho-emotional distress of this category of people: increased neuroticism, sudden aggression, depression, irritability and emotional lability. Diagnosis by questionnaire allows to detect manifestations of the disease in the early stages of development.
Influence of small Doses of Electromagnetic Oscillations on the features of Coronavirus Reproduction
Authors: Нloba Oleksandr P. , Rybalko Svitlana L. , Garnyk Tetyana P. , Medkov Igor V. , Zalevsky Olexandr V. , Humankova Olga S. , Mykhailova Oksana S.
Published: November 2021

Aim: To study the influence of small doses of electromagnetic oscillations on the molecular-biological state and features of coronavirus reproduction.
materials and methods: The study was conducted at the Laboratory of Experimental Chemotherapy of viral infections of the State Institution “L.V. Gromashevsky Institute of Epidemiology and Infectious Diseases of the National Academy of Medical Sciences of Ukraine” and was based on the materials of the educational institution “Ukrainian Resource Center of Educational Innovations”. During 90 days, with the use of hardware and software complex “Vim Vitae” (from Latin – life force), an experimental study on the registration and analysis of antiviral activity of small doses of electromagnetic oscillations on a biological object (coronavirus pathogens) was organized based on the author’s methodology “Life without medicines”.
Results: A study of the antiviral effect of low doses of electromagnetic oscillations on an experimental model of coronavirus – virus of transmitted swine gastroenteritis – showed that small doses of electromagnetic oscillations inhibited coronavirus reproduction by 1.25-2.4 lg TCD50 (tissue cytopathogenic dose 50).
Conclusions: We believe that in the near future, traditional diagnostic methods will be replaced by new, information-metric, widely available technologies based on smartphones and tablets, which allow not only very quickly and accurately to detect disease, but also learn a lot of other information important for effective therapy. In perspective, these technologies will become a convenient method for self-monitoring and remote interaction with the doctor, for maintaining own health and the health of loved ones.
Psychological Rehabilitation During a Coronavirus pandemic. Legal Aspects
Authors: Terzi Olena O. , Gladchuk Igor Z. , Shpak Igor V.
Published: November 2021

Aim: To analyse the legal regulation of the provision of psychological assistance during the coronavirus pandemic.
materials and methods: The research methods were chosen with the aim of the study in mind. In order to establish objectivity and validity of scientific provisions, conclusions, during the research, a set of general scientific and special scientific methods was used, in particular such as: (1) the formal legal method was used to analyse the legal and ethical foundations for providing psychological assistance during the coronavirus pandemic; (2) using the comparative legal method, the approaches of national legislation and international standards to the provision of psychological assistance during the COVID-19 pandemic were clarified; (3) the forecasting and modeling method was used to develop practical recommendations regarding the importance of analyzing the legal regulation of the provision of psychological assistance during the coronavirus pandemic and others in the future; (4) the method of systems analysis made it possible to study the legal regulation of the provision of psychological assistance during the coronavirus pandemic; (5) the historical and legal method made it possible to identify the features of the evolution of legal regulation of the provision of psychological assistance during pandemics.
Conclusions: The COVID-19 pandemic has exacerbated existing health deficiencies, including a shortage of psychologists. States should initiate medical training programs, including for psychologists and psychotherapists. It should be noted that psychological assistance during a coronavirus pandemic should be based on the following principles: accessibility; continuity; focus; interdisciplinary; educational nature of interventions.
Application of magnetoledtherapy and magnetostimulation in the Treatment of Chronic finger wound After Injury. Case Report
Authors: Senejko Michał , Pasek Jarosław
Published: November 2021

Physical medicine and its wide therapeutic potential shows that this methods can be used in many fields of medicine.It pertains also the wide application of the low-frequency magnetic fields and low-energy optical light emitted by diodes LED.The aim of the study is to present the beneficial results of the treatment a 92-year-old female patient in whom in addition typical pharmacological treatment magnetoledtherapy and magnetostimulation treatments were used, lead to complete healing of the chronic wound.Together with a surgical cleansing of the wound, its daily hygiene comprising of change dressings and pharmacotherapy, additional treatments supporting wound healing such as magnetoledtherapy and magnetostimulation were implemented. A series of 40 daily treatments were carried out, except Saturday and Sunday, with a positive effect.
THE STATE OF REPRODUCTIVE HEALTH OF WOMEN WITH HYPERPROLIFERATIVE PATHOLOGY OF THE ENDOMETRIUM
Authors: Nikitina Iryna M. , Horban Nataliia Ye. , Mykytyn Kseniia V. , Kondratiuk Kateryna O. , Smiian Svitlana A. , Kalashnyk Nataliia V. , Gerevich Nadiya V.
Published: November 2021

The aim: To study and analyze the dynamics of women’s reproductive health in Ukraine as a factor in population reproduction and to study the features of menstrual disorders in Ukraine in 2010-2019. In women of reproductive age with hyperproliferative pathology of the endometrium without atypia.
Materials and methods: A descriptive epidemiological study was conducted using data from the departmental statistical reporting of the Ministry of Health of Ukraine on the number of cases of gynecological pathology for 2010–2019. The peculiarities of menstrual function in patients of reproductive age with atypical hyperproliferative pathology of the endometrium were studied. We examined 84 patients of the gynecological department of the Sumy Regional Clinical Perinatal Center with a diagnosis of hyperproliferative pathology of the endometrium without atypia, who sought medical help during 2017-2020 for hyperplastic processes of the endometrium in reproductive age (18 to 49 years). All patients were divided into three groups, up to group I women with endometrial hyperplasia without atypia (HGE) (n = 30); Group II – patients diagnosed with endometrial polyps (n = 30); group III included patients with combined hyperproliferative pathology (uterine body polyps and endometrial hyperplasia without atypia) (n = 24).
Results: As a result of the conducted systematic analysis it was established: the higher the prevalence of PMC, the higher the frequency of diseases of the genitourinary system and some gynecological diseases. This is confirmed by the calculated coefficients of correlation of the prevalence of PMC with the frequency of diseases of the genitourinary system (r = 0.75, p<0.001), salpingitis (r = 0.63, p<0.001) and endometriosis (r = 0.42, p<0, 05). The assessment of the relative risk of gynecological diseases has shown that the greatest attention needs to be paid to improving the diagnosis of infertility and endometriosis, as well as the prevention and treatment of salpingitis and uterine cancer. When women with menstrual disorders go to the gynecologist, it is necessary to pay attention to the presence of hyperproliferative pathology, and if women have other chronic diseases, offer rehabilitation of these foci, which can further have a positive effect on reproductive health.
Conclusions: The highest rates of menstrual irregularities were found in women with endometrial hyperplasia without atypia and a combination diffuse hyperplasia with endometrial polyps in contrast to patients with only endometrial polyps. Menstrual irregularities can be considered as a marker and indicator of dysfunction of the genitourinary system and the presence of a hyperproliferative process at the prehospital stage.
EVALUATION OF THE EFFECTIVENESS OF TREATMENT OF PATIENTS WITH TEMPOROMANDIBULAR JOINT DYSFUNCTION AFTER MANDIBULAR FRACTURES ACCORDING TO X-RAY EXAMINATION
Authors: Skrypa Olga L.
Published: November 2021

The aim: On the basis of radiological data to evaluate the effectiveness of our developed treatment complex of patients with temporomandibular joint dysfunction after mandibular fractures.
Materials and methods: To achieve this goal, 92 patients hospitalized in the department of surgical dentistry of the Chernivtsi Regional Clinical Hospital were examined for traumatic fractures of the mandible with functional disorders of the TMJ. 46 patients (main group) were treated according to the treatment method developed by us, and 46 patients (control group) were treated with the traditional method. Patients underwent orthopanthography and radiography of the temporomandibular joint according to Schuller. Statistical processing of research results was carried out using commonly used methods of variation statistics.
Results: After 12 months of studies in patients of the main group, unilateral narrowing of the joint space was determined in 6,52 ± 1,83% of persons p, p1 0.05.The number of persons with unilateral expansion of the joint space according to Rtg, in the main group decreased by 2,3 times relative to the data before treatment.
Conclusions: Timely treatment of musculoskeletal disorders with the help of pharmacological and physiotherapeutic methods proposed by us, allowed, to a large extent, to eliminate clinical, radiological and ultrasound symptoms of temporomandibular joint dysfunction in patients with post-traumatic lesions of mandibule. This was confirmed by the improvement of the data of the conducted functional researches.
PECULIARITIES OF MOTOR ACTIVITY OF RATS IN SIMULATION PHARMACOLOGICAL DEPRESSOGENIC STATES
Authors: Sydorenko Antonina , Lutsenko Ruslan , Kniazkova Iryna , Liakhovska Nataliia , Lutsenko Olga
Published: November 2021

The aim: To analyze and compare the features of changes in the motor activity of rats on the background of pharmacological models of depressive disorders.
Materials and methods: Depressive-like state was simulated on 40 mature male Wistar rats using: reserpine (15 mg/kg), clonidine (0.1 mg/kg), haloperidol (0.25 mg/kg). The control group was given as a single dose 0.5 ml of a 0.9% sodium chloride solution intraperitoneally. After 3, 12, 24, 48 and 72 hours from the beginning of the experiment, changes in motor activity in the “open field” test were examined by the number of crossed squares, the calculation was carried out within 5 minutes.
Results: Reserpine at a dose of 15 mg/kg caused probable motor activity disorders in rats in the “open field” test during all study periods. The most pronounced inhibition of motor activity was observed within 12-48 hours from the beginning of the experiment. 3 hours after clonidine administration, the number of crossed squares decreased by 310% (p<0.001), after 12 hours – by 180% (p<0.001), after 24 hours – by 140% (p<0.001), after 48 hours – by 50% (p<0.005) in comparison with the control group. On 3rd day, the motor activity of rats was almost completely restored. The use of haloperidol after 3 hours most significantly impaired the motor activity of rats in the “open field” test, and its recovery was observed after 24 hours.
Conclusions: Reserpine inhibited the motor activity of rats, most pronounced from 12 to 48 hours of the experiment. Clonidine inhibited mainly in the first hours of the study. Haloperidol impaired motor activity at 3rd and 12th hours of observation.
FEATURES OF PSYCHOPATHOLOGICAL REACTION IN PARENTS WHOSE CHILDREN SUFFER FROM CHRONIC MUSCULOSKELETAL DISORDERS
Authors: Belov Oleksandr , Loiko Yevhen , Mazaikina Iryna , Pototska Iryna
Published: November 2021

The aim: Was exploring features of psychopathological reaction in parents whose children suffer from chronic musculoskeletal disorders.
Materials and methods: Clinically, 40 fathers and 64 mothers of children suffering from chronic muscular motor pathologies using M. Hamilton’s Depression and Anxiety Scale and Buss-Durkee Hostility Invertory were examined.
Results: It was revealed that the foundation of psychopathological reactions of parents to the chronic illness of children is depressive (from 68,2% to 97,0%) and anxiety (from 40.9% to 100.0%) disorders, and dyssomic disorders as well (from 18.2% to 93.9%), asthenic (from 9.1% to 81.8.%), affective lability (from 9.1% to 36.4%), apathetic (from 4.5% to 42.4%), cognitive (from 4.5% to 42.4%) and obsessive-phobic (from 4.5% to 39.4%) disorders. Mothers with longer and shorter periods of illness in children showed higher levels of depression (20.82 ± 5.94 and 20.26 ± 6.59 respectively) and anxiety (19.06 ± 5.00 and 17, 77 ± 5.65) compared with fathers (17.44 ± 8.78 and 10.82 ± 6.21, respectively; 14.72 ± 5.57 and 14.95 ± 4.45), but fathers showed higher levels of aggression 65.59 ± 10.42 and 63.21 ± 10.31 (respectively versus 55.27 ± 6.97 and 49.72 ± 10.00).
Conclusions: А high level of psychopathological reaction in mothers is detected at short periods of disease, and in fathers it significantly grows as the duration of child’s illness increases.
ILLEGAL INTERNET PHARMACIES AS A THREAT TO PUBLIC HEALTH IN EUROPE
Authors: Gutorova Nataliya O. , Pashkov Vitalii M. , Soloviov Oleksii S.
Published: November 2021

The aim: This article aims to raise awareness and stimulate serious discussion about the dangers of illegal Internet pharmacies for patient safety and public health, the necessity to improve legal instruments, and unite the efforts of governments, professional organizations, and civil society for combating this activity.
Materials and methods: This study is based on the Medicrime Convention, empirical and analytical data of the WHO, Interpol, Europol, NABF, Directive 2011/62/EU of the European Parliament and of the Council of June 8, 2011, the regulatory acts and juridical practice of Ukraine, experts interview of pharmacy practicians, analysis of websites. Totally 18 laws and papers, 34 court judgments, 50 websites were analyzed, six experts were interviewed. Dialectical, comparative, analytic, synthetic, system analyses and sociological research methods were used.
Results: Illegal Internet pharmacies are widespread in Europe, especially during the COVID-19 pandemic. This black market poses a severe threat to patient safety and public health as falsifying, substandard, and smuggled medicines are sold through these channels. Without any exception, all illegal pharmacies sell prescription drugs without any prescriptions. Regulatory and protective legal instruments at the national and international levels are insufficient to counter the Internet trade in medicines.
Conclusions: The widespread proliferation of illegal Internet pharmacies in Europe requires European states to work together to protect patient safety and public health. A legal mechanism needs to be established to exchange information and combat illegal pharmaceutical activities on the Internet at the international level. At the national level, it is necessary to strengthen control over the wholesale of prescription medications to prevent them from entering the black market.
FEATURES OF THE ULTRASTRUCTURE OF THE SKIN OF WHITE RATS 60 AND 90 DAYS AFTER MODELING OF PORTAL HYPERTENSION
Authors: Hrytsevych Nazar R. , Vereschaka Volodymyr V.
Published: November 2021

The aim: The aim of the research was to study the features of the ultrastructure of the skin of white rats 60 and 90 days after modeling of portal hypertension.
Materials and methods: The investigations were performed on male white nonlinear rats. The animals of the first (control) group underwent a sham operation. In rats of the second group, portal hypertension was simulated by applying a ligature to the portal vein. 60 and 90 days after the start of the experiment, a biopsy was taken from the anterior abdominal wall for electron microscopy research.
Results: It was shown that skin in intact animals (control group) was of typical structure before beginning of experiment and 60 and 90 days after a sham operation. 60 days after the start of the experiment, we found severe edema of the basal and spinous layer of the epidermis, breakdown of intercellular contacts, edema of endotheliocytes, their perivascular edema, leukocytes infiltration, edema of mitochondria and lysosomes. 90 days after the start of the experiment, ultrastructural changes in the skin were more pronounced. Ultrastructural changes of microvessels were characterized by narrowed lumen. Endothelial cells had significant edema.
Conclusions: Тhe data obtained should be taken into account when performing surgical interventions to prevent complications in the formation of the scar.
AMBIENT AIR PROTECTION IN THE SYSTEM OF PUBLIC HEALTH AND BIOLOGICAL SECURITY LEGAL PROVISION
Authors: Pashkov Vitalii , Trotska Maryna V. , Nikolenko Liudmyla M.
Published: November 2021

The article examines the legal and regulatory basis for ambient air protection as an essential element of the environment that affects biological security the health and livelihoods of the population. Proper legal regulation of ambient air protection is important in the implementation of various measures aimed at preserving its quality and, accordingly, preventing possible adverse effects on human health. Ambient air protection is a certain activity directed at reducing the number of pollutants that get into the air by one means or another. In the process of environmental protection in general and ambient air protection in particular, the legal basis and case law are important components that aimed to minimize the occurrence of potential hazards that could threaten the health and lives of the population, and in case of such situations, identify the causes of their occurrence and respond to them proportionally.
A CLINICAL CASE OF COEXISTENT PARASITIC LIVER AND GASTRIC LESIONS CAUSED BY CLONORCHIASIS
Authors: Belokonev Vladimir , Gritsaenko Andrei I. , Nikolaev Alexey , Larina Tatiana
Published: November 2021

Clonorchiasis is a parasitic disease caused by Clonorchis sinensis. Parasite colonies can develop not only in the bile and pancreatic ducts but also in the gastric wall. This is confirmed by the described clinical case of perforated gastric ulcer, the morphological study of which revealed parasite colonies in the wall of the organ.
Vers un règlement européen concernant l'IA ?
Authors: Duarte Magalie , Biot Paquerot Guillaume , Bidan Marc
Published: November 2021

Cette étude (en deux parties) aborde, détaille et décrypte ce qu’il est désormais possible de nommer un « cadre règlementaire » innovant pour et sur l’intelligence artificielle en Europe. Ce premier papier se concentre sur la description de ce qui est innovant et intéressant et le second sur les éventuels impacts managériaux et organisationnels que cet AIA pourraient déclencher au sein de nos écosystèmes de plus en plus data-centrés.
Le digital et les établissements d’enseignement supérieur ?
Authors: Tran Sébastien
Published: November 2021

La digitalisation est un phénomène qui a commencé il y maintenant plusieurs années dans l’enseignement supérieur (on parlait avant de FOAD pour Formation Ouverte A Distance, de E-Learning, etc.) et a fait naître de nombreuses innovations, tant sur le contenu que sur l’ingénierie pédagogique en passant même par l’émergence de nouveaux modèles économiques et de nouveaux acteurs (le CNED en France, l’université de Phoenix aux Etats-Unis, OpenClassrooms, etc.).
El clero católico y la construcción nacional argentina (1862-1916)
Authors: Di Stefano Roberto
Published: November 2021

A diferencia del resto de los países latinoamericanos —con la sola excepción de Costa Rica—, la Argentina nunca separó jurídicamente la Iglesia y el Estado. Los gobiernos «liberales» del período conocido como «organización nacional» (1862-1880) y del llamado «orden conservador» (1880-1916), incluidos los que condujeron el país durante los ásperos debates públicos que acompañaron la sanción de las «leyes laicas» de la década de 1880, vieron en el cristianismo un elemento fundamental de la «civilización» y en la Iglesia Católica una aliada necesaria para la construcción de la nación, del Estado y del «progreso». El artículo, sobre la base de fuentes ministeriales y parlamentarias, analiza los consensos y disensos en el modo en que la elite dirigente concibió la agencia del clero católico en el proceso de construcción nacional.
La observancia del silencio en las Clarisas de Antigua Fundación de Santiago de Chile (siglos XVII-XIX)
Authors: De La Taille-Trétinville Alexandrine , Aguirre Durán Marcelo
Published: November 2021

El siguiente artículo analiza la observancia de la Regla de santa Clara de Asís por parte de las religiosas del Monasterio de Santa Clara de Antigua Fundación (Santiago de Chile). Específicamente, en este texto proponemos una revisión de la práctica cotidiana del silencio intramuros, a fin de verificar de qué modo la observancia de la Regla de Santa Clara presenta variantes propias en Chile con respecto a Hispanoamérica, considerando la distancia temporal y geográfica de sus orígenes. Para ello exploramos la relación de estas monjas con la jerarquía eclesiástica de la diócesis a partir, principalmente, de una selección de visitas pastorales y de sínodos de Santiago durante los siglos XVII, XVIII y XIX. Este estudio colabora con el conocimiento de la Orden de santa Clara en Chile pues, hasta ahora, no existe una obra monográfica que abarque, bajo la perspectiva de las prácticas de los tradicionales votos monásticos, los cuatro siglos de historia de esta comunidad de mujeres.
Research on Institutional Advantages and Dilemma of Contemporary Chinese Public Participation in Public Administration
Authors: Ma Qiongli
Published: November 2021

Based on the background that China is accelerating socialist administrative management reform with Chinese characteristics, this paper selects public participation in public administration as a research object and outlines the existing institutional arrangement of public participation in public administration. By focusing on the institutional advantages and dilemma of Chinese public participation in public administration, the paper analyzes from the national macro level, local government medium level and grassroots micro level and further proposes the suggestions on the ways to promote Chinese public participation in public administration.
Transforming the Pension Industry Based on Aged Care Quality Reports
Authors: Mu Hongan , Dai Ziwei , Long Manting , Xu Junru , Liang Caihong , Jiang Tao
Published: November 2021

With the intensification of population aging, the importance of the pension industry has gradually been reflected. The purpose of this study is to find mainly challenges in the pension industry by analyzing the Australian Aged Care Quality Reports. In recent years, Aged Care Quality reports have played a positive role in improving the service quality of aged care institutions and strengthening risk management. This study found that the risk factors in the aged care quality report are the key factors for the upgrading of the pension industry. With the help of traditional text data analysis and mining methods, we can effectively provide new growth points and breakthrough links for the upgrading of the pension industry. This research found the upgrading of the pension industry in the construction of basic hardware and software facilities, the level of informatization and intelligence, the improvement of the quality of aged care services, the improvement of medical problems, and the training of professionals. The research methods proposed in this study are significant to the upgrading of the current pension industry.
State-Public University Contractual Relationship Impact on Student’s Accessibility Rights: The Agency Theory Perspective
Authors: Kimoga Joseph
Published: November 2021

The state-public university contractual relationship constrains public universities to be driven by the state expected level of quality output of graduates. The relationship reduces institutional substantive and procedural autonomy in specific key areas like student admission. In order to achieve good results consonant to the state support, universities are directed to ensure strict scrutiny of those they admit. This locks out many qualifying students from accessing studies at state-funded institutions. This study uses the perspective of agency theory to assess the impact of state – public university contractual relationship on student’s accessibility rights. The interpretive phenomenological analysis enabled to appreciate data collected through self-administered questions given to seven participants in four public and regional universities. The analysis bases on parameters of selection and admission. The study recommends capital grant, national ranking of academic units, and policy imperatives for special interest groups as the means by which sub-Saharan higher education institutions can maximise students’ access rights
Analisis Kadar Rhodamin B Pada Blush-On Menggunakan Metode Spektrofotometri Uv-Vis
Authors: Taupik Muhammad , Adam Mustapa Moh , Sitti Gonibala Sintia
Published: November 2021

Cosmetic are mixture of materials that are ready to be used on the outside of the body. One type cosmetics makeup that is often used is Blush-On. This Blush-On cosmetics has a distinictive red color, so it issu red color, so it is suspected that there is still a misuse in the addition of Rhodamine B to Blush—n cosmetics, especially cosmetics that are not registered to BPOM (The Nationalof Drug and Food Control). Based on the PERMENKES RI No. 445/Menkes/Per/V1998 concerning certain dyes declared dangerous it is a synthetic dye Rhodamine B which is one of the dyes that is prohibited for use in-cosmetics products because the fidings of BPOM from 2014 to 2015, Rhodamine B is still used as one of the dyes. This study aims to knowthe misuse of the addition of synthetic dye Rhodamine B to Blush-On cosmetics and to know how much Rhodamine B is contained in the Blush-On cosmetic samples. The results of the qualitative test with the staining method on the Blush-On cosmetics samples A,B,C,D, and E, it is sample E that produces a clear reddish color that has he potential to contain Rhodamine B . Furthemore, it is continued with a quantitative test by using Uv-Vis Spectrofotometry, and it obtains levels of Rhodamine B in sample E is 9,98mquantitative test by using Uv-Vis Spectrofotometry, and it obtains levels of Rhodamine B in sample E is 9,98mg/g.
SKRINING FITOKIMIA DAN UJI AKTIVITAS ANTIOKSIDAN JANTUNG PISANG GOROHO (Musa acuminafe L.) DENGAN METODE 1,1-DIPHENYL-2-PICRYLHIDRAZYL (DPPH)
Authors: S.Si.,M.Si.,Apt Dr. Widysusanti Abdulkadir , S.Si.,M.Si Dr. Apt. Hamsidar Hasan , Alamsyah Ading Ading
Published: November 2021

Goroho banana (Musa acuminafe L.) has its own characteristics and is one of the local varieties of banana that is not widely known to people outside North Sulawesi. In addition, it is commonly used as an antioxidant. Antioxidants are substances that can improve the function of layers of blood vessels, inhibit blood platelet aggregation where it can stimulate the production of Nitric Oxide, which causes the relaxation of blood vessels and can reduce the sensitivity of Low-Density Lipoprotein (LDL) to the effects of free radicals. Therefore, this research aims to determine the chemical content and antioxidant activity of Goroho Banana (Musa acuminafe L.) by using DPPH (1,1-diphenyl-2-picrylhydrazyl) method. Besides, the extraction of samples is carried out by employing extraction graded with n-hexane, chloroform, ethyl acetate, and ethanol solvents. Findings reveal that Goroho banana (Musa acuminafe L.) peel extract contains Alkaloid and Flavonoid compounds. Meanwhile, the value of antioxidant activity indicates that the IC50 value for n-hexane, chloroform, ethyl acetate, and ethanol extracts are 6.38, 5.48, 5.11, 4.19 ug/ml, respectively. In conclusion, the IC50 value discloses that the antioxidant activity is in a strong category.
UJI AKTIVITAS ANTIBAKTERI EKSTRAK METANOL DAUN KECUBUNG (Datura metel L.) TERHADAP BAKTERI Streptococcus pneumonia DAN Klabsiella pneumonia
Authors: Andy Suryadi A. Mu’thi , Adam Mustapa Moh , Hiola Faramita , Basiru Sintiya
Published: November 2021

Infectious disease is a disease caused by microbes, including bacteria. One of the microorganisms that often causes infectious disease is Streptococcus pneumoniae and Klabsiella pneumoniae. Based on empirical data, plant that has antimicrobial potential is amethyst leaves (Datura metel L.). This study aims to know the antibacterial activity and concertration of amethyst leaves (Datura metel L.) against Streptococcus pneumoniae and Klabsiella pneumonia. This is an experimental study which includes antibacterial activity test, MIC (Minimum Inhibitor Concertration) test, MFC (Minimum Fungicidal Concertration) test, and bacterial potency test. The finding shows that the antibacterial activity test of amethyst leaves (Datura metel L.) methanol extract is able to inhibit bacterial growth of Streptococcus pneumonia at a minimum inhibitor concertration of 15% and an optimum concertration of 50% with an average of 16.33 mm and 19.30 mm. Meanwhile, for Klabsiella pneumoniae, the minimum inhibitor concertration is 20% and the optimum concertration is 50%, with an average of 13.82 mm and 17.73 mm. this is based on the results of One Way Anova data (a 0.01) with a 99% confidance level.
Analisis Manajemen Pengelolaan Logistik Sediaan Farmasi dan Perbekalan Kesehatan di Instalasi Farmasi
Authors: Susanti Abdulkadir Widy , Madania Madania , S. Tuloli Teti , Rasdianah Nur , Akuba Juliyanty
Published: November 2021

Drug management is a set of optimally conducted activities related to the aspects of drug planning, procurement, storing, distribution, and extermination. This was done to achieve the proper drug amount, types, supply, maintenance, and medication. Earlier observstion revealed problems in managing pharmaceutical stock and consumables, where some of the stocks are empty. This qualitative descriptive research focus on identifying pharmaceutical logistic stock and health supplies comprising drug planning, procurement, storing, distribution, and extermination in the pharmaceutical unit of Gorontalo. The primary data were obtained from questionnaires based on technical guidance by the health ministry while the secondary were obtained from related documents. Based on the findings, the pharmaceutical stock planning and storing process at the pharmacy unit did not meet the health ministry standards, which is opposite to the procurement, distribution, and extermination process.
Analisis Kadar Metabolit Sekunder, Histokimia, dan Aktivitas Antioksidan Akar Acalypha indica L.
Authors: Agustina Novia , Istiqomah Nurul
Published: November 2021

Acalypha indica L. is a species of wild plant that has secondary metabolites are used as medicine, but the usage is not optimized yet. The objective of of this study was to determine secondary metabolites content, location and distribution of secondary metabolites, and also the capacity for antioxidant. Secondary metabolites content was determined included phenol, flavonoids, tannin of chloroform and methanol extracts from Acalypha indica L. root, using spectrophotometre. Histochemical test was done by making fresh sliced preparation which was reacted with reagent. Antioxidant activity was determined by using DPPH method. The result of this study showed that secondary metabolites content of chloroform extract, were phenol 9,89 ± 0,77 %GAE, flavonoids 5,87 ± 1,40 %QE, and tannin 3,33 ± 1,21 %GAE, while methanol extract were phenol 45,11 ± 4,86 %GAE, flavonoids 19,87 ± 0,61 %QE, and tannin 6,76 ± 0,31 %GAE. Histochemical test showed that phenol, flavonoids, tannin, and alkaloids were found in Acalypha indica L. root. Antioxidant activity showed the IC50 value was 161,81 ± 7,88 μg/mL for chloroform extract and 92,81 ± 4,33 μg/mL for methanol extract.
Efektivitas Terapi Antibiotika Demam Tifoid Pada Pediatrik Di Rumah Sakit X Kota Kediri
Authors: Oktaviana Feny , Noviana Puput
Published: November 2021

Typhoid fever has the highest incidence in children. Treatment for typhoid fever uses antibiotics. Increasing bacterial resistance to antibiotics is a global problem. This study was conducted to determine the differences in the effectiveness of antibiotics in the treatment of typhoid fever on the heat-free time and the length of treatment for pediatric patients in the inpatient ward of the X Hospital, Kediri City. This research is a descriptive analysis research. A retrospective study was conducted using medical records in 2017. Data were collected by purposive sampling. Data were taken on pediatric patients with typhoid fever aged 5-11 years. The statistical test used to analyze the effectiveness of therapy in pediatric patients with typhoid fever was performed using the Kruskal-Wallis test. The sample used in this study were 38 pediatric patients. The antibiotics used were ciprofloxacin 52.63%, ceftriaxone 28.95%, cefuroxim 10.53%, and penicillin 7.89%. The results of the analysis of differences in the effectiveness of antibiotics against heat-free time obtained a sig value 0.05 (0.947) and a sig value 0.05 (0.329) for the length of treatment. There was no significant difference in heat-free time and length of treatment between ceftriaxone, cefuroxim, ciprofloxacin and penicillin.
Analisis Faktor Kepemimpinan Transformasional Dan Motivasi Sebagai Antisedence Dari Kepuasan Kerja Terhadap Kinerja Pegawai Dalduk & KB Kota Semarang
Authors: Mochamad Ainan  , Andhi Supriyadi  , Syamsul Hadi  , Dyah Palupiningtyas
Published: November 2021

Keberhasilan organisasi dipengaruhi kinerja pegawainya, dalam pelaksanaannya faktor kepemimpinan, motivasi dan kepuasan kerja berperanan penting. Tujuan penelitian ini menganalisa dan menjelaskan berpengaruhnya kepemimpinan dan motivasi melalui kepuasan kerja kepada kinerja pada pegawai Dinas Pengendalian Penduduk dan Keluarga Berencana (DALDUK & KB) Kota Semarang. Metode sensus digunakan untuk sampling yaitu teknik mengambil data dari semua anggota populasi yang dijadikan sampel yaitu 100 orang dengan kuestioner. Penelitian ini menghasilkan kepemimpinan transformasional, motivasi dan kepuasan kerja mempengaruhi dengan positif juga signifikan kepada kinerja pada pegawai DALDUK & KB Kota Semarang. Saran yang dapat diberikan, agar kantor Badan Pertimbangan Jabatan dan Kepangkatan (Baperjakat) Kota Semarang dalam menempatkan kepala Dinas yang mampu memotivasi untuk  peningkatan kinerja pegawai
Pengaruh Kualitas dan Desain Produk Terhadap Keputusan Pembelian (Survey pada Produk Envygreen Skincare)
Authors: Dinda Dwi Guntari  , Prihartono Aksan Halim
Published: November 2021

Tujuan penelitian ini adalah untuk mengetahui pengaruh kualitas dan desain produk terhadap keputusan pembelian produk Envygreen Skincare. Metode kuantitatif dengan analisis regresi linier berganda dipakai dalam melakukan penelitian ini, yang kemudian data diolah menggunakan bantuan aplikasi statistik SPSS.v.26.0. Populasi yang digunakan yakni seluruh pengguna produk Envygreen Skincare yang pengambilan sampelnya memakai teknik purposive sampling, sehingga didapatkan sampel sebesar 50 orang. Kuesioner dipakai sebagai instrumen pembantu dalam mengumpulkan data dengan skala likert yang terdiri dari 33 pertanyaan dan telah disusun berdasarkan indikator atau dimensi masing-masing variabel. Dari hasil penelitian terbukti bahwa secara parsial tiap-tiap variabel kualitas dan variabel desain produk mempunyai pengaruh yang signifikan terhadap keputusan pembelian, serta secara simultan variabel kualitas dan variabel desain produk bersama-sama mempunyai pengaruh yang signifikan terhadap keputusan pembelian produk Envygreen Skincare.
Pengaruh Citra Merek dan Kepercayaan Merek Terhadap Loyalitas Merek Sego Njamoer (Studi pada Gerai Sego Njamoer Foodcourt Royal Plaza Surabaya)
Authors: Abdul Ghofur  , Supriyono
Published: November 2021

Sego Njamoer adalah merek makanan cepat saji olahan jamur terpopuler di Surabaya yang sedang mengalami tren fluktuasi penjualan pada gerai Foodcourt Royal Plaza Surabaya. Fluktuasi tersebut dikarenakan turunnya loyalitas merek pelanggan dalam memilih dan membeli makanan Sego Njamoer. Penelitian ini bertujuan untuk mengetahui pengaruh citra merek dan kepercayaan merek terhadap loyalitas merek Sego Njamoer pada gerai Sego Njamoer Foodcourt Royal Plaza Surabaya. Menggunakan pendekatan kuantitatif. 70 responden pelanggan Sego Njamoer diambil sebagai sampel penelitian menggunakan teknik purposive sampling dari populasi pelanggan yang berkunjung di gerai Sego Njamoer Foodcourt Royal Plaza Surabaya. Pengolahan data dilakukan dengan teknik analisis PLS (Partial Least Square). Hasil penelitian menunjukan citra merek dan kepercayaan merek berpengaruh positif dan signifikan terhadap loyalitas merek Sego Njamoer pada gerai Sego Njamoer Foodcourt Royal Plaza Surabaya.

Kata Kunci: Citra merek, Kepercayaan merek, Loyalitas merek, Sego Njamoer