bluuebunny/crossref_metadata_2025 huggingface dataset:
Phenylbutyrate rescues the transport defect of the Sec61α mutations V67G and T185A for renin
Authors: Sicking Mark , Živná Martina , Bhadra Pratiti , Barešová Veronika , Tirincsi Andrea , Hadzibeganovic Drazena , Hodaňová Kateřina , Vyleťal Petr , Sovová Jana , Jedličková Ivana , Jung Martin , Bell Thomas , Helms Volkhard , Bleyer Anthony J , Kmoch Stanislav , Cavalié Adolfo , Lang Sven
Published: January 2022

The human Sec61 complex is a widely distributed and abundant molecular machine. It resides in the membrane of the endoplasmic reticulum to channel two types of cargo: protein substrates and calcium ions. The SEC61A1 gene encodes for the pore-forming Sec61α subunit of the Sec61 complex. Despite their ubiquitous expression, the idiopathic SEC61A1 missense mutations p.V67G and p.T185A trigger a localized disease pattern diagnosed as autosomal dominant tubulointerstitial kidney disease (ADTKD–SEC61A1). Using cellular disease models for ADTKD–SEC61A1, we identified an impaired protein transport of the renal secretory protein renin and a reduced abundance of regulatory calcium transporters, including SERCA2. Treatment with the molecular chaperone phenylbutyrate reversed the defective protein transport of renin and the imbalanced calcium homeostasis. Signal peptide substitution experiments pointed at targeting sequences as the cause for the substrate-specific impairment of protein transport in the presence of the V67G or T185A mutations. Similarly, dominant mutations in the signal peptide of renin also cause ADTKD and point to impaired transport of this renal hormone as important pathogenic feature for ADTKD–SEC61A1 patients as well.
PENGARUH CORPORATE GOVERNANCE DAN CORPORATE REPUTATION TERHADAP EMPLOYEE ENGAGEMENT (Studi pada sebuah perusahaan logistik multinasional di Indonesia)
Authors: Haryanto Haryanto
Published: January 2022

The purpose of this study was to determine whether there is a relationship between Corporate Governance and Corporate Reputation on Employee Engagement. This research was conducted at a multinational logistics company in Indonesia in December 2020. The data collection method was carried out by means of a questionnaire via google form which was distributed to employees. Data analysis was performed using Statistical Product and Service Solutions with classical tests. Researcher found several things, including Corporate Governance partially has a significant and positive effect on Employee Engagement, Partially Corporate Reputation has a significant and positive effect on Employee Engagement, Corporate Governance and Corporate Reputation simultaneously have a significant and positive effect on Employee Engagement.
ANALISIS DAYA SAING EKSPOR JASA NEGARA ASEAN
Authors: Tita Efrida , Santoso Slamet , Purnomo Rochmat Aldy , Riat Winanto Asis , Hamidah Choirul
Published: January 2022

This research aims to determine the export competitiveness of asean country's service sector’s. The data used to support this research is secondary data in the form of service sector export data, total exports, and Gross Domestic Product (GDP) Constant Price for the study period in 2015-2019. The analysis tools used are Klassen Typology, Location Quotient (LQ), Revealed Competitive Advantage (RCA), and Overlay analysis. Based on the results of overlay analysis by combining three analytical tools (Klassen Typology, LQ, and RCA), shows that the export competitiveness of the service sector owned by Singapore is insurance and pension services; charges for the use of intellectual property; telecommunications, computer, and information services; and other business services. Malaysia's export competitiveness of the service sector is personal, cultural, and recreational services, while the Philippines is telecommunications, computer, and information services. Meanwhile, Indonesia and Vietnam are ASEAN countries that do not have export-competitive service sectors.
ANALISIS KUALITAS PELAYANAN DENGAN MENGGUNAKAN QUALITY FUNCTION DEPLOYMENT PADA MODERN LAUNDRY CIREBON
Authors: Sentosa Roby , Lahindah Laura , Gandajaya Linda
Published: January 2022

Service Quality has a close relationship with customer satisfaction. Service quality provides an encouragement to customers to establish strong ties with the company. Customer satisfaction is created if customer’s needs or expectation can be met through the quality of services provided. The good or bad quality of the service depends on the ability of the service providers to consistently meet customer’s needs or expectation. The research was conducted on a business unit that offered services in the case of per-kilogram clothes washing, namely Modern Laundry. As a business unit that has a mature age, Modern Laundry must be able to know and make services that are needed and demanded by its customers. To be able to do it, a method is needed in this study. The method used in this study is QFD (Quality Function Deployment). The QFD method provides technical requirements by meeting the customer's voice with the company's voice. With the use of this method, companies are able to find out what is the customer's needs and demand, what services must be maintained, improved and eliminated. This study tested the validity and reliability so that the data used in this study were valid and reliable. The results of this study are there are several characteristics of customer needs and desires that must be prioritized by Moden Laundry. Not only these characteristics in this study the technical characteristics that need to be prioritized also by Modern Laundry.
Board Diversity and Financial Performance of the Nigerian Listed Firms: A Dynamic Panel Analysis
Authors: Sani Abdullahi
Published: January 2022

The effect of board diversity on organisational performance has continued to be given attention by policymakers, non-governmental agencies, and academic communities. It has been established that boardroom diversity enhances the corporate boards’ monitoring capacity and mitigates the agency costs, which positively influences the firms’ performance. Despite the advantages of constituting diverse boards, the corporate governance framework guiding the operations of such firms does not contain any specific requirement on board diversity. Hence, empirical studies need to stress more on the relevance of boardroom diversity to firms’ value in the Nigerian context. Therefore, this paper examines the effect of board diversity on financial performance of the Nigerian listed firms. The study utilised the balanced panel data of 70 firms for a period of 8 years (2012 to 2019) using a two-step system generalised method of moments (GMM) framework. This study indicates a positive and significant relationship of board gender diversity (BGD) and Foreign directors (FD), with financial performance. However, the effect of CEO financial expertise on the firms’ return on assets (ROA), return on equity (ROE), and return on sales (ROS) appear positive but insignificant. Consequently, the Nigerian listed firms should attach more value to constitute a smaller board size with a considerable number of female and foreign directors to maximise their performance.
Institutional support for High-tech manufacturing sectors
Authors: Dontsova O.  I.  ,  Abdikeev N.  M. , Zotov V. M. 
Published: January 2022

Currently, a large-scale reform of the development institutions of the Russian Federation is planned and has begun to be implemented. The end result of the reform should be a fundamentally new ecosystem of investment support for technological growth processes. One of the important goals of a such ecosystem formation is to ensure the high competitiveness of the domestic world’s economy, as well as the compliance of the goals, strategies and policies of the development institutions in accordance with the Unifed Plan for achieving National Goals until 2030*. The authors of the paper concluded that today there were only general features of the reform of development institutions and were not defned such features as: future algorithms for institutions functioning, mechanisms of functioning, project selection mechanisms, project management mechanisms for monitoring the effectiveness of development institutions.
Assessment and forecasting of the russian regions attractiveness as a factor of Interregional migration
Authors: Fattakhov R.  V.  , Nizamutdinov M.  M.  , Atnabaev A.  R.  , Akhmetzyanova M. I. 
Published: January 2022

Nowadays, one of the most important tasks of the state in the framework of ensuring sustainable socio-economic and demographic development of the country is the regulation of migration processes. The changes observed in a complex political situation, including the impact of sanctions and pandemics, have affected on the priorities transformation of the population when choosing a potential place of residence. In this regard, it is important and timely to identify trends and factors of population migration, as well as to assess the level of migration activity using modern economic and mathematical methods of analysis. These issues are most relevant for those regions where there is a migration outﬂow of the population. In order to identify the factors inﬂuencing a human behavior when making a decision to change their place of residence, a component analysis was conducted on 22 indicators of socio-economic development of 67 subjects of Russia. This process identifed fve main components. The obtained results formed the basis for assessing the level of attractiveness of the territories and further cluster analysis of the regions. This caused to the formation of four clusters, including the subjects of the Russian Federation with a similar level of socio-economic development. Combining the results of the multi-factor assessment made it possible to determine the complex level of socio-economic development for each region. At the next stage of the study, the identified relationships between the socio-economic development of the regions and the migration level were formalized using the methods of regression analysis. The obtained simulation results let the authors develop a forecast of the migration processes dynamics, taking into account the implementation of the inertial and optimistic scenarios for the development of the socioeconomic situation.
Digital asset management in a Digital environment: algorithms and services
Authors: Stepnov I.  M. , Fedotova М.  A. 
Published: January 2022

The paper describes the issues of value-based management of digital assets (DA). The relevance of the study is determined by the growth in the volume of digital assets under management and the need to develop new approaches to measuring their value. The subject of the research was the transformation of approaches to assessment and management in the digital economy. First of all, this concerns new types of assets. The goal is to form an integrated approach to the value management of assets in the digital environment. The paper uses methods of description, scientifc analysis and synthesis based on the specifc principles of valuation for management purposes defned in the article. The results are based on the digital assets identifcation for valuation and management purposes. The newly identifed types of DA require the use as traditional methods of discounting cash ﬂows, as well as more brand new complex models for measuring value added, including the theory of real options. For this purpose, authors compared the classical approach to value-based management (based on value levers) with the recommendation algorithms which is growing trend for active use. Digital asset management involves the management model adaptation based on key value factors, characteristics, as well as features of the legal turnover. Decentralized systems are of the greatest interest and scientifc novelty in this area. They can provide the required level of trust and scalability. The paper shows the implementation of effective valuebased management requires a justifcation and selection of a digital environment, which is proposed as a decentralized fnancial services. As a result, the represented comprehensive algorithm is able to combine classical approaches to determining value for management purposes with the modern digital solutions (in particular, with machine learning methods). There is made an advisable conclusion to use this approach for valuation based on smart options for managing new types assets.
Sales management. Methodology of Improving the efficiency of the company’s sales system
Authors: Nazarov A.  I. 
Published: January 2022

The unyielding efforts to develop a methodology for building a sales management system are yet another proof of its relevance. These efforts will continue, as the business community needs a sustainable and consistent operation model. The last 7 years have seen a general economic downturn and a slow recovery. Such topics as improvement of business effciency and investment performance, validation of costs, enhancement of management quality and cost controls have been gaining in relevance. Efforts to improve effciency of businesses, primarily of those which are associated with high costs and risks are becoming increasingly important. Since 2015, the author has been receiving an ever-increasing number of client enquiries on the subject “Sales Management”. The research described was started in 2010 and it is still ongoing. The bulk of the research work and experiments, the results of which are described in the article, were completed in 2016. The novelty of the proposed approach lies in its systemic analysis of the entire managerial paradigm governing the corporate sales system. It does not offer a description of feasible operation methods but it does offer a logically consistent chain of managerial decisions following the “if…, then…” principle. The proposed methodology is logically complete and organised in a hierarchical pattern where decisions made are arranged in a graded order according to their importance. The proposed research approach relies in part on the principles of holistic thinking and it is focused on the analysis of the hierarchy of managerial decisions made and their interplay. The research was conducted while working with the clients who sought sales management consultancy services. The study results proved the effectiveness of the developed model and its high reliability for the analysis of different sales systems when one has to make managerial decisions designed to improve the sales system (though the study results are to a lesser extent applicable to retail sales). The prospects for the practical application of the results generated by this study are encouraging: modern companies need a sustainable model to analyse and streamline their sales management system. The research methodology and conclusions form the basis of the education programmes and training courses offered at the Graduate School of Corporate Management at the Russian Presidential Academy of National Economy and Public Administration (RANEPA) and Moscow Business School.
Criterios de patologías que requieren ingreso a la unidad de cuidados intensivo
Authors: Casas Rodríguez Javier , Zambrano Córdova Jaime Roberto , Vélez Muentes José Ricardo , Vera Pinargote Ronal Gabriel
Published: January 2022

El objetivo de este ensayo consistió en analizar los criterios de selección de enfermedades que pueden ser consideradas como motivos de ingreso en la UCI, para lo cual se ha hecho una revisión de varios documentos, consensos internacionales, artículos de investigación en medios electrónicos. Se ha encontrado que se hace necesaria la implementación de sistemas de gestión de calidad en las unidades de cuidado intensivos, que permitan llevar un mejor registro de la enfermedad del paciente, el tratamiento indicado por el médico tratante, reduciendo también los costos operativos de los hospitales o clínicas. En relación a las morbilidades encontradas como criterios de ingreso se tiene a la Hipertensión Arterial Crónica representa la patología que con mayor frecuencia genera situaciones que ameritan el ingreso a las UCI, seguida de la insuficiencia renal crónica y el cáncer. Se recomienda contar con criterios de triaje objetivos, éticos, transparentes, aplicados equitativamente y de público conocimiento, para facilitar la atención de calidad a los pacientes que deban ingresar a la UCI.
Estrategias de comunicación para la marca “Lácteos de Mi abuela” en la ciudad de Zaruma, el Oro
Authors: Jaramillo Zúñiga Carlos Alejandro , Mora Espinoza Carlos Gabriel
Published: January 2022

El mercado de lácteos se vio afectado por la pandemia de la COVID-19 como la mayoría de los sectores económicos a nivel país y mundial, por lo tanto, lo que se busca es que a través de las estrategias de comunicación la empresa pueda implementar acciones para lograr una mejor captación de clientes a través del uso eficaz de las redes sociales y contenido de interés del público de objetivo. Se procedió a realizar una investigación descriptiva, de tipo no experimental. Para recabar la investigación se aplicó la técnica del cuestionario a través de una encuesta digital en la cual previamente se formularon las preguntas en una operacionalización de variables. La cantidad de la muestra a investigar fue de 394 personas. Una vez realizada la investigación se diseñaron las estrategias de comunicación que se fundamenta básicamente en relaciones con la prensa, relaciones con clientes. La aplicación de estas estrategias de comunicación tiene un retorno de un dólar con veintiséis centavos por cada dólar invertido.
Development of a risk assessment profile tool to determine appropriate use of SARS-CoV-2 rapid antigen detection tests for different activities and events in Ireland, since October 2021
Authors: Mallon Patrick WG , Horgan Mary , McAloon Conor G , Lunn Peter D , Little Julian , Beck Andrew , Bennett Alexandria , Shaver Nicole , Conway Aileen , O’Regan Rhea , Whelan Barbara ,   Rapid Testing Expert Advisory Group, Ireland
Published: January 2022

We describe the development of a risk assessment profile tool that incorporates data from multiple domains to help determine activities and events where rapid antigen detection tests (Ag-RDT) could be used to screen asymptomatic individuals to identify infectious cases as an additional mitigation measure to reduce transmission of SARS-CoV-2. The tool aims to stratify, in real time, the overall risk of SARS-CoV-2 transmission associated with common activities and events, and this can be matched to an appropriate Ag-RDT testing protocol.
To What Extent Ethnolinguistics as a Discipline Is the Certain Scientific Paradigm Realizing?
Authors: Bartmiński Jerzy
Published: January 2022

In the article the issue of ethnolinguistics’ thesaurus compiling and scientific paradigm of this discipline is discussed. The review of contemporary ethnolinguistic researches is made. The problems of coherence of ethnolinguistics as a scientific discipline are considered. The thesaurus compiling is proposed to distribute to the stages; one of them it would be descriptive dictionary which steps back to the principles of normative dictionary creation. Side by side with the terms which maintenance has come to an agreement, the thesaurus would maintain also the terms specific for separate ethnolinguistics’ schools.
Suriyeli Mülteci Krizinin Türkiye ve Avrupa Birliği İlişkisine Yansıması: Dünya Sistemleri Analizi Üzerinden Bir Değerlendirme
Authors: ÖZTÜRK Tolga , BOYACI Ece
Published: January 2022

Göç insanlık tarihiyle başlayan ve günümüze kadar gelen bir olgudur. Türkiye, jeopolitik konumu gereği tarih boyunca birçok göçmenin hedef ya da geçiş bölgesi olmuştur. 2011 yılında başlayan Suriye İç Savaşı, Türkiye’yi ve Avrupa’yı sosyal, siyasal ve ekonomik olarak olumsuz etkisi altına alan kitlesel bir göç dalgasına neden olmuştur. Bu çalışmanın amacı, Türkiye ve Avrupa Birliği’ne üye olan ülkelerin Suriye İç Savaşı dönemindeki ilişkilerinin göç hareketleri bağlamında değerlendirilmesidir. Suriye kaynaklı kitlesel göçün, Türkiye ve Avrupa Birliği ilişkilerine etkisi “Dünya Sistemleri” kuramı bağlamında ele alınmıştır. “Çevre”den, “Yarı-Çevre”ye oradan da “Merkez”i hedefleyen göç hareketinin siyasal etkilerinin kuram çerçevesinde sınanarak değerlendirilmesi hedeflenmiştir. Dolayısıyla, Suriye, Türkiye ve Avrupa Birliği’nin göç ve güvenlik politikalarının, birbirlerine olan politik bakış açısının, göç unsuruyla nasıl şekillendiği de Sistem Okulu yaklaşımıyla ele alınmıştır.
A 15 años de la revolución pinguina: ¿En qué están las reformas estructurales en educación?
Authors: Carrasco Bahamonde Juan Antonio
Published: January 2022

El presente trabajo propone un análisis del ciclo de política educativa y cambio institucional en la educación chilena. Las movilizaciones de los estudiantes secundarios lograron conectar sus demandas con el cuestionamiento público del modelo educativo y la necesidad política de una reforma estructural. A partir de la revisión de literatura se propone una reconstrucción de la secuencia a través de la cual la problematización del mercado educativo es abordada en los planes de reforma. No obstante, el sentido ex post que asumen aquellas agendas de reforma, mantención y cambio, no son evidentes, suponen una sintaxis compleja donde los problemas de la política educativa se configuran como un campo en disputa. El artículo concluye que no es posible comprender el campo de producción de la política educativa en Chile en las últimas décadas, sin considerar la intensificación de la protesta estudiantil, aunque quedan preguntas abiertas sobre las perspectivas para futuras reformas regulativas orientadas a la equidad.
Escenarios posibles en un mundo post pandemia
Authors: Cerrillo Omar , Castro Rascón Aristeo
Published: January 2022

El presente ensayo analiza el ejercicio que muchos pensadores de las ciencias sociales y humanidades han generado en torno a la creación de escenarios posibles para un futuro pospandémico. Se parte de un escenario político trazado por García Canclini en los albores de la pandemia, donde se presentan procesos de desciudadanización, despolitización y desglobalización, mismos que se acrecentarán ante la llegada del COVID-19. Con el inicio de la pandemia se viene un mundo de virtualidad, no entendida desde la comunicación digital, sino, como lo plantea Latour, desde la posibilidad. Este marco nos permite analizar precisamente los principales escenarios que algunos pensadores, en concreto Slavoj Žižek y Byung-Chul Han, han desarrollado. Nuestra propuesta se centra, más que en generar visiones de futuro, en aprovechar la pausa que nos ha dado el mundo pandémico para ir, lateralmente, hacia escenarios posibles múltiples y no determinantes, poniendo al centro los valores de la prudencia, la ciudadanía y la ética.
PICTORIAL ELEMENTS OF INDIAN MINIATURE PAINTING
Authors: Rao K. Mrutyunjaya
Published: January 2022

This  paper discusses the magnificent contribution of Indian miniature painting as the torch bearer of Indian visual culture for the future generations with transitions and various idioms.  It’s Visual imagery raised to paramount importance from the auxiliary position to the religious text. Artist has not imitated from nature  but imbibed  the spirit of divinity  and greater love  and passion on Indian culture. Its function is religious as well as decorative. “Horrorvacuue” the desire of filling space is the common characteristics of an Indian is often appears in  Indian painting. The articulations of  line, colour , space  are discussed in this  article The Climatic conditions might been allowed the Indian painter  to experience unusual color patterns. The deep rooted  veneration for religion and nature and to fulfill the taste of his patron. Which made him as a distinct artist  in  the world forever.
Kualitas Pembangunan Desa Berbasis Data Desa Presisi (Kasus: Desa Neglasari, Kecamatan Dramaga, Kabupaten Bogor, Jawa)
Authors: Natalia Grace , Sofyan Sjaf
Published: January 2022

Fakta-fakta keberhasilan pembangunan desa di Indonesia belum sesuai dengan kondisi dan kenyataan yang sesungguhnya. Alhasil, kualitas pembangunan desa yang diharapkan masih jauh dari harapan. UUD 1945 menyatakan bahwa kualitas pembangunan desa dapat dilihat dari lima aspek kesejahteraan rakyat (kesra): (1) sandang, pangan, papan; (2) pendidikan dan kebudayaan; (3) kesehatan, pekerjaan dan jaminan sosial; (4) kehidupan sosial, perlindungan hukum dan HAM; dan (5) infrastruktur dan lingkungan hidup. Untuk memotret kualitas pembangunan desa melalui 5 aspek kesra ini, dibutuhkan data presisi, mengingat berbagai indeks atau pengukuran kualitas pembangunan desa di Indonesia berbasis data yang tidak akurat. Penelitian ini bertujuan untuk menentukan standar kualitas pembangunan desa berbasis data desa presisi, mengukur kualitas pembangunan desa berbasis data desa presisi, dan merekomendasikan kebijakan dan program perbaikan kualitas pembangunan desa. Metode penelitian yang digunakan adalah metode kuantitatif dengan pendekatan Drone Participatory Mapping (DPM) dan didukung data kualitatif melalui studi literatur, observasi dan wawancara mendalam. Hasil penelitian ini menunjukkan bahwa kualitas pembangunan Desa Neglasari cenderung rendah. Rekomendasi untuk perbaikan kualitas pembangunan desa adalah program dan atau kebijakan peningkatan 8 variabel kategori rendah dan 2 variabel kategori sedang.

Kata kunci: Data desa presisi, Kualitas pembangunan desa, Pengukuran.
HUBUNGAN PERUBAHAN SOSIAL PASCA PEMBANGUNAN INFRASTRUKTUR JEMBATAN SURAMADU DENGAN TARAF HIDUP MASYARAKAT PEDESAAN
Authors: Sulaisiyah  , Fredian Tonny Nasdian  , Zessy Ardinal Barlan
Published: January 2022

Pembangunan merupakan suatu proses terencana yang dapat menimbulkan perubahan-perubahan sosial. Khususnya di Pulau Madura terdapat Pembangunan Jembatan Suramadu (Surabaya-Madura) yang akan menjadi tonggak perubahan pada kedua sisi daerah khususnya di Pulau Madura yang menjadi target pembangunan. Tujuan penelitian ini adalah untuk menganalisis hubungan perubahan sosial yang terjadi akibat pembangunan dengan taraf hidup masyarakat pedesaan. Metode penelitian yang digunakan adalah metode kuantitatif dengan metode survei yang didukung dengan data kualitatif di Desa Sukolilo Barat, Kecamatan Labang, Kabupaten Bangkalan, Provinsi Jawa Timur. Jumlah responden 46 orang yang terdiri dari nelayan, petani, non petani dan non nelayan. Pemilahan responden melalui metode pengambilan acak stratifikasi. Hasil penelitian ini menunjukkan bahwa terdapat hubungan yang signifikan antara strata sosial sebagai bagian dari perubahan sosial dengan taraf hidup masyarakat pedesaan.

Kata Kunci: Pembangunan Infrastruktur, Perubahan Sosial, Taraf Hidup, Masyarakat Pedesaan
Efektivitas Instagram Sebagai Media Promosi Produk Olahan Pertanian Kopi Di Rumah Kopi Sunda Hejo
Authors: Firdaus Adzania Mutiara , Hadiyanto
Published: January 2022

Agroindustri merupakan kegiatan industri dengan memanfaatkan hasil pertanian yang diolah menjadi produk olahan pertanian. UMKM merupakan agroindustri skala kecil dan menengah yang menjual produk lokal. Dalam pengembangan usaha UMKM, perlu dilakukan kegiatan promosi untuk memperkenalkan produk kepada konsumen secara luas, salah satunya menggunakan media sosial Instagram. Tujuan penelitian ini adalah menganalisis karakteristik pesan dalam media sosial Instagram, menganalisis keterdedahan terhadap akun @sundahejo, menganalisis efektivitas Instagram sebagai media promosi, menganalisis hubungan antara karakteristik konsumen dengan efektivitas Instagram sebagai media promosi, menganalisis hubungan antara karakteristik pesan dalam media sosial Instagram dengan efektivitas Instagram sebagai media promosi, dan menganalisis hubungan antara keterdedahan terhadap akun @sundahejo dengan efektivitas Instagram sebagai media promosi. Penelitian ini menggunakan metode survei dengan data kuantitatif berupa kuesioner yang didukung oleh data kualitatif berupa wawancara mendalam. Jumlah responden dalam penelitian ini adalah 50 responden. Hasil penelitian menunjukkan Instagram efektif dalam menstimulasi perhatian, ketertarikan dan keinginan responden. Memasuki tahap action efektivitas Instagram tergolong cukup efektif mendorong responden dalam melakukan tindakan terhadap produk kopi Sunda Hejo.

Kata Kunci: Kopi lokal, Media promosi Instagram, Model AIDA
The role of algorithms in enhancing the effectiveness of studying pronouns in the 6th form: the semantic and grammatical-orthographic aspects. Part 1. Lexicogrammatical classes of pronouns and their correlation with the nominal parts of speech
Authors: Sulnichenko V. N.
Published: January 2022

The paper aims to outline the role of algorithms in improving the effectiveness of studying pronouns at school level. The study demonstrates the correlation between the lexico-grammatical classes of pronouns and the nominal parts of speech (nouns, adjectives, and numerals). The focus of analysis is the grammatical features, declension, and spelling of pronouns. Additionally, the basic spellings and usage of pronouns with prepositions are analysed. The research uses the technique of structuring and processing grammatical material in the form of diagrams, tables, algorithms which are created in the classroom. Thus, they facilitate a successful acquisition of the grammatical material on the syllabus. The effectiveness of the proposed methodology for studying pronouns was proved during a research and methodological investigation. This conclusion is valid as sixth formers learnt to 1) view pronouns in conjunction with their general grammatical meaning; 2) distinguish the morphological features of pronouns; 3) classify pronouns according to their semantic affinity with the nominal parts of speech; 4) decline pronouns and build normative grammatical forms of words; 5) classify the lexico-grammatical classes of pronouns in accordance with their correlation to the nominal parts of speech; 6) identify grammatical homonyms among lexico-grammatical classes of pronouns. The paper substantiates the practicality of the algorithmic approach to teaching the above-mentioned grammatical material in the 6th form. This is evidenced by schoolchildren’s ability to differentiate between pronouns and other parts of speech, discern morphological errors while building word forms and correct them in compliance with algorithms.
The sense-making mechanisms in O. Mandelstam’s poem "Palace Square"
Authors: Gryaznova A. T.
Published: January 2022

The article which is written within the framework of linguopoetics analyses the sense-making mechanism from a cognitive perspective. The basic tool used to create this mechanism in O. Mandelstam’s poem "Palace Square" is vertical context. The vertical context of the poem under study is a complex structure consisting of not only separate linguistic units (historisms, archaisms, proper nouns, lexemes characteristic of religious discourse, quotations, and allusions) which have national and cultural specific features and require a commentary, but also a number of linguistic paradigms based on various principles of grouping. These principles are: taxonomic (passive vocabulary, including obsolete lexemes and religious discourse words), thematic (the lexico-semantic fields "The Roman Empire", "The Russian Empire", "Pushkinian Petersburg" and the semantic field "Faith"), figurative (metaphtonymies, aposiopesis, metaphors, metonymies, similes) as well as the relations between the elements of these paradigms. The units representing metaphtonymies which facilitate the formation of a "bunch of meanings" according to Mandelstam and the markers of aposiopesis (a trope requiring a deep ethnocultural analysis, which implies a "visualization" of the depicted urban landscape) pose the greatest difficulty in the process of analysis. The principles of repetition, antithesis, assimilation constitute the basis of the language composition of the poem. These principles interact with one another structuring the vertical context with respect to the artistic merit and making its semantic perspective broader.
Развитие письменной речи учащихся: методический потенциал аналитических заданий
Authors: Erokhina E. L.
Published: January 2022

The paper examines methodological conditions necessary to achieve the expected learning outcomes of studying Russian as a school subject. To be more specific, careful attention is paid to such aspects of teaching school students as written text creation, analysis, and assessment of their own and other learners’ speech acts from the standpoint of the communicative task, situation, and the conditions of communication. The performed analysis of learners’ final (‘December’) essays and detailed (comprehensive) answers written in the Unified State Exam (EGE) in the humanities testifies to the existence of serious shortcomings in teaching school students to produce written speech spontaneously. One of the most significant problems is the mass creation of pseudo-texts by school students in conjunction with written speech templating. The major reasons for this phenomenon lie in methodological flaws such as the replacement of writing skills formation by preparation for a specific essay type. Other flaws consist in the lack of attention to the specific features of writing as a speech activity and in the prevalence of teaching practices related to producing texts on the basis of clichés and templates suggested by the teacher. The aim of the paper is to substantiate the point that teaching writing will only become effective in case learners are aware of the specific nature, features, and laws of writing treated as a type of speech activity. The analysis of methodological research into learners’ speech development issues, works on speech studies and the psychology of speech combined with a comparative analysis of learners’ detailed written answers enabled the author to obtain the results presented in this paper. The method employed in the study is modelling a system of tasks on the basis of a rhetorical approach. The analytical tasks described in the study are specially tailored for school students. Doing them, learners will definitely gain an insight into the dialogic nature of written speech as it is addressed to an ‘imaginary interlocutor’. They will also become aware of the distinctive features of a writing person’s motivation as well as primary objectives that have to be achieved at each stage of writing. The excerpts from school-leavers’ essays with comments made by the author confirm the effectiveness of the proposed methodology.
Isolation and susceptibility patterns of bacteria associated with lung diseases
Authors: Chinyelu Umeaku  , Harrison Eze
Published: January 2022

Lung diseases have been a worldwide health problem,with high endemicity in developing countries. Bronchopneumonia remains the main disease of the lung. Despite advances in modern medicine, there is no-effective drug available that stimulate lung function, offer protection to the lung from damage or help to regenerate pulmonary cells destroyed by disseminated bacteria. There is an urgent need for effective drugs to replace/supplement those in current use. This study was embarked upon to evaluate the effect of Asplenium bulbiferum leaf extracts on nosily infected mice with Streptococcus pneumoniae isolate of suspension containing 5x106 cells/ul. Streptococcus pneumoniae was obtained from human specimen, identified through cultural, morphological and biochemical examination, in addition, polymerase chain reaction (PCR) technique was performed using universal primers to support the identification process. The antibacterial activity was carried out using agar well diffusion technique. Tube dilution technique was used to determine the minimum inhibition concentration (MIC) and minimum bactericidal concentration (MBC) using double fold serial dilution at concentrations of 400mg/ml to 25mg/ml. The effect of the leaf extract was evaluated by treating mus musculus mice (WBC count 4.5x103) with sub-MIC of A. bulbiferum extracts after being nosily infected with S. pneumoniae and appearance of disease septum with 11.3x103 WBC count after 5days from infection. The photochemical analysis revealed the presence of alkaloids; phenolics, tannins, saponins, flavonoids, steroids and glycosides. The ethanolic extract exhibited more activity than the aqueous extract against S.aureus most followed by S. pneumoniae, H. influenza and K. pneumoniae was the least. After treating the infected mice with the plant extract for 6 days from infection, the WBC count reduced to 5.1x103ml which is normal range and the mice were healthy with good physiological behaviour. For the infected untreated mice, the WBC and other immunological parameters remain high even after 16 days from infection. The study showed that Asplenium bulbiferum possessed antibacterial properties and could serve as alternative therapy for ameliorating lung infections.
A case report of nonepisodic angioedema with eosinophilia in a young Japanese female followed up with serum cytokines and immunoglobulins
Authors: Masaaki Minami  , Takefumi Suzuki
Published: January 2022

NEAE (Nonepisodic angioedema associated with eosinophilia) is a relatively common allergic disease in East Asia in which angioedema is confined to the extremities, is transient and does not recur, and is not accompanied by fever or highly elevated IgM. In this study, we report a case of NEAE disease with edema of the extremities in a young female who was able to be followed up with serum cytokines and serum immunoglobulins as biomarkers. Our results suggest that not only clinical findings but also serum biomarkers are useful in monitoring the disease status of NEAE.
Pengaruh Animasi Interaktif dengan Model Explicit Instruction terhadap Prestasi Matematika
Authors: Soeryaningsih Novita , Gaspar Besin , Isman Soubar
Published: January 2022

Keberhasilan proses belajar tidak hanya ditentukan oleh guru atau, tetapi siswa ikut pula menentukan keberhasilan dalam proses pembelajaran matematika. Dalam Kompetensi Dasar perhitungan luas permukaan bangun gabungan adalah hal yang dianggap mempunyai tingkat kesulitan yang tinggi. Untuk itulah diperlukan sebuah media animasi interaktif Geo Gebra yaitu sebuah aplikasi matematika bersumber terbuka yang dirancang khusus untuk tujuan pendidikan. Model pembelajaran Explicit Instruction adalah suatu pendekatan pembelajaran yang dirancang khusus untuk menunjang proses belajar siswa yang berkaitan dengan pengetahuan deklaratif dan  prosedural yang tersruktur dengan baik yang diajarkan dengan pola selangkah demi selangkah.  Dengan menggunakan media animasi interaktif dan model pembelajaran explicit instructiondapat meningkatkan prestasi belajar matematika utamanya pada perhitungan luas permukaan kubus dan balok.
Edukasi Titik Kritis Halal pada Kelompok Usaha Jasa Pencucian Pakaian
Authors: Kusumawati Dwi Endah , Fatmawati Dina
Published: January 2022

Dalam kaitannya dengan aktivitas sehari-hari, jaminan produk halal tidak hanya terbatas pada usaha makanan maupun minuman, namun perlu merambah pada berbagai sector usaha salahsatunya adalah usaha pencucian pakaian. Usaha pencucian pakaian saat ini menjadi salah satu bisnis yang menjanjikan karena sangat membantu bagi seseorang yang aktivitas pekerjaannya sangat padat, namun banyak usaha pencucian pakaian yang kurang memperhatikan aspek kehalalan pada hasil cuciannya. Hal tersebut terjadi karena rendahnya pengetahuan awal terkait aspek jaminan halal pada produk cucian pakaian khususnya titik kritis halal pada jasa usaha pencucian pakaian. Kegiatan pengabdian masyarakat ini bertujuan untuk memberikan informasi terkait titik kritis halal pada kelompok usaha jasa pencucian pakaian berdasarkan kajian bioteknologi. Edukasi pada kelompok jasa pencucian pakaian dilakukan melalui sosialisasi dan penyebaran leaflet langsung ke pelaku usaha jasa pencucian pakaian. Penyampaian materi edukasi meliputi pengenalan sistem jaminan produk halal sesuai dengan Keputusan Kepala Badan Penyelenggaran Produk Jaminan Halal no. 57 tahun 2021 dan titik kritis halal jasa pencucian pakaian. Adanya kegiatan edukasi ini membuat peserta memiliki tambahan pengetahuan terkait proses pemisahan pakaian, penggunaan bahan utama, tambahan dan penolong pada produk pencucian pakaian. Berdasarkan hasil kegiatan disimpulkan bahwa terdapat peningkatan pengetahuan dan pemahaman peserta terkait dengan jaminan produk halal dan titik kritis kehalalan suatu produk khususnya pencucian pakaian. Kata kunci: Laundry; titik kritis kehalalan; produk halal
PENGARUH DEBT TO EQUITY RATIO, RASIO PASAR DAN TOTAL ASSETS TURN OVER TERHADAP RETURN SAHAM PADA PERUSAHAAN PROPERTY YANG TERDAFTAR DI ISSI
Authors: Sari Noni Ayunda , Rahayu Sri , . Zufrizal , Rangkuti Lusi Elviani
Published: January 2022

This study aims to see how much Debt To Equity Ratio (DER), Market Ratio (Price Book Value) and Total Asset Turn Over (TATO) Influence On Property Companies Listed in ISSI. The number of samples in this study as many as 10 samples of the company and research conducted from 2016-2018. The data analysis methods used to test hypotheses are descriptive analysis test, classic Assumption Test, Multiple linear analysis test, and Hypothesis Test which is processed in a statistical manner and using Statistic for product and service solution (SPSS) program version 25.00 year 2020. The results showed that variable Debt To equity Ratio (DER), Market Ratio (Price book value) and Total Asset Turn Over (TATO) simultaneously have a significant influence on Stock Return. While partially the effect varies, Debt To Equity Ratio and Total Asset Turn Over have no significant effect on Stock Return. While the market ratio (Price Book value) has a significant influence and has a negative direction towards Stock Return.
PENGARUH NETWORKING CAPITAL , CASH FLOW dan GROWTH OPPORTUNITY TERHADAPRETURN ON ASSET (ROA) DI PERUSAHAAN TEKSTIL DAN GARMEN YANG TERDAFTAR DI BURSA EFEK INDONESIA
Authors: Indriani Ayu , Ningsih Heny Triastuti Kurnia , Riana Zenni , Elviani Sri
Published: January 2022

The purpose of this study was to determine whether Net Working Capital, Cash Flow and Growth Opportunity partially or simultaneously affect the Return On Asset (ROA) of the Textile and Garment Sub-Sector Companies listed on the IDX. Data collection techniques are using secondary data taken from Indonesia Stock Exchange website, Multiple Linear regression Analysis Technique, Hypothesis Test, namely T Test and F Test, Determination Coefficient Test using the SPSS Version 20 application.The results of this study reveal that the Net Working Capital variable partially does not have a significant effect on Return On Asset, the Cash Flow variable partially has no significant effect on Return On Asset, and Growth Opportunity partially has a significant effect on Return On Assets, while the Net Working Capital variable has no significant effect on Return On Asset. Simultaneously, Cash Flow and Growth Opportunity have no effect on Return On Assets.
PENGARUH ARUS KAS TERHADAP HARGA SAHAM PADA PERUSAHAAN MANUFAKTUR SUB SEKTOR MAKANAN DAN MINUMAN YANG TERDATAR DI BEI
Authors: Pasaribu Amanda Agustia , Nasti Nilawati , . Mas’ut , Andri Shofwan
Published: January 2022

This study aims to the effect of cash flow on stock prices in food beverage sub-sectorMaufacturing Companies listed on the Indonesia Stock Exchange. This study has a population of 21 companies that are Food and Beverage Sub Sector Manufacturing Companies listed on the Indonesia Stock Exchange during 2018-2020 which are then determined to be sampled using a purposive sampling method to obtain a sample of 13 Food and Beverage Sub Sector Manufacturing Companies by Specified criteria. The analytical method used is quantitative descriptive. Data analysis includes data feasibility test, regression analysis, and hypothesis testing partially and simultaneously. The result of this study indicate that (1) Operating Cash Flow has no effect on stock prices, (2) Investment Cash Flow has no effect on stock prices, (3) Funding cash flow has a significant effect on stock prices, (4) the effect operating cash flow, investment cash flow, and funding cash flow has no effect on stock prices.
ETIKA PROFESI AUDITOR DALAM MEMODERASI PENGARUH INDEPENDENSI DAN KOMPETENSI AUDITOR ATAS KUALITAS AUDIT
Authors: Nurfauziah Farah Latifah , Sayekti Fitria Ningrum , Utami Citra Kharisma
Published: January 2022

The purpose of this study is to identify: (1) the effect of competence and independence of auditors on audit quality, (2) how auditor ethics moderates the effect of auditor competence and independence on audit quality. The sample of this study was 50 representatives of public accounting firm auditors in the city of Bandung. The validity and reliability of the questionnaire were tested before the study. The prerequisite tests for the analysis carried out were the normality test, the multicollinearity test, and the heteroscedasticity test. The data analysis method used is simple regression analysis and multiple regression analysis. The results show that H1 is rejected where there is no effect of Auditor competence on Audit Quality because the regression coefficient is 0.05 and the tcount is 0.365 ttable 2.0452. The results of the H2 test also show that there is no effect of auditor independence on audit quality because the regression coefficient is 0.222 and the tcount is 1.407 ttable 2.0452. While the H1a test shows that Auditor Ethics moderates the effect of Auditor competence on audit quality positively with a significance of 0.034. The H2a test shows that Auditor Ethics does not moderate the effect of Auditor independence on audit quality with a significance value of 0.399.
THE PRACTICE OF WALIMAT AL-‘URS: Competing Sharia and Tradition in Aceh
Authors: Nasir Muhammad , Juliandi Budi
Published: January 2022

Abstract: One of the most heated debate in a diverse and plural legal system in such as Indonesia, is the issue of harmonization of sharia and tradition. This paper is an attempt to study the extent to which the harmonization of Islamic law and tradition in Aceh. Using a qualitative approach, this paper focuses on walimat al-‘urs tradition. The author argues that differences between tradition and shari’a may become an avenue for new configuration that would be preserved as a uniting factor in the foreseeable future Indonesia. The data was obtained from in-depth interviews with important local figures. The research shows that sharia through ‘urf theoretical framework could not accepts the richness of indigenous entities.

Keywords: walimat al-‘urs, ‘urf, sharia, Aceh
CONSCIOUSNESS TO LIBERATE: In Search of the Political Paradigm of Muhammadiyah
Authors: Al-Hamdi Ridho
Published: January 2022

Abstract: This paper examines the political paradigm of Muhammadiyah in thinking and behaving because Muhammadiyah can survive to surpass political impediments for more than a century ago. Methodologically, it is qualitative research by utilising documentary study and in-depth interviews as the data-gathering technique. The finding demonstrates that “consciousness to liberate” is the political paradigm of Muhammadiyah. This paradigm has three interrelated dimensions: transcendental dimension, humanistic dimension, and modernity dimension. The former indicates the prophetic consciousness, the middle demonstrates the liberation theology, and the latter denotes the values Muhammadiyah’s goal. Therefore, the Muhammadiyah consciousness to strives for prophetic missions not merely restricted to liberate humankind from colonisation, oppression, backwardness, and poverty but also to liberate mustadh‘afin from unfair policies and liberal systems. 

Keywords: Muhammadiyah, consciousness, political paradigm, liberation, al-Mâ‘ûn