bluuebunny/crossref_metadata_2025 huggingface dataset:
ORTHODONTIC MALOCCLUSSION DIAGNOSING BY LATERAL HEADFILMS
Authors: Nabatchikova L P , Horoshilkina F Y , Chobanyan A G
Published: October 2016

Results of measurement of lateral headfilms at 159 adult surveyed with I-st class occlusion and IInd and III-th class malocclussion. 6.720 changes are executed. The complex method of the analysis of lateral headfilms including offers A.Bjork, Hassund, A.M.Schwarz and own is applied.The way of an individualization of the sizes is developed at definition of 9 types: 1 - the vertical sizes of the basis of a skull; 2 - positions of forward and back points of basis of the top jaw in a horizontal direction; 3 - congenital types of a profile of the face; 4 - definitions of the basic direction of growth of obverse department of a skull; 5 - arrangements of point Articulareb a biometric articulate field; 6 - an inclination occlusion planes. It is recommended to be guided by the average us average and individualized norms of a structure of obverse department of a skull.
PHARMACOTHERAPY OF PULMONARY HYPERTENSION DURING PREGNANCY AND POSTPARTUM PERIOD
Authors: Ushkalova E A , Runihina N K , Novikova I M
Published: October 2016

Pregnancy in women with pulmonary hypertension is associated with a high risk of poor outcomes and high maternal mortality rates, therefore contraindicated in this category of patients. Yet the world has accumulated some experience of pregnancy in women with pulmonary hypertension, who refused abortion, or in whom the disease was diagnosed in later stages of gestation. In this paper results of randomized and observational studies of the main and supportive pharmacotherapy in pulmonary hypertension are given, characteristics of modern drugs for the treatment of pulmonary hypertension and data on their safety during pregnancy are recommended, as well as expert opinion on drug therapy in pregnant women with pulmonary hypertension.
ARSENAL OF MODERN MEDICAL LINERS USED IN DENTISTRY (REVIEW OF LITERATURE DATA)
Authors: Chen Wei , Elouazzani Mohamed , Kazanceva G P
Published: October 2016

The article is devoted to the review of the modern literary data regarding prevalence of caries of teeth according to WHO, arsenal of medical liners used for treatment of deep caries of teeth. Influence of different groups of medical liners to reparative function of pulp of tooth is noticed in the article.
TOPOGRAPHIC ANATOMY OF THE VALVE OF INFERIOR VENA CAVA IN THE EARLY FETAL PERIOD OF HUMAN ONTOGENESIS
Authors: Lyaschenko D N
Published: October 2016

On the material torsos of the 100 fetus 16-22 weeks of development were studied topographic anatomy valve of inferior vena cava in the early fetal period of human ontogenesis. The paper used a complex morphological studies: macroscopic-microscopic dissection, the method cuts for N.I. Pirogov, gistotopografical method. The study obtained morphometric data on the anatomy of the valve, provides a detailed quantitative analysis of it’s skeleton-, syn- and golotopia.
EFFECTS OF IONIZING RADIATION ON THE ENERGY EXCHANGE IN DIFFERENT CEREBRAL CORTEX
Authors: Ilicheva V N , Ushakov B N
Published: October 2016

The comparative characteristic changes gistoenzimological profile in phylogenetically different areas of the cerebral cortex of rats after a single exposure at a dose of 0.5 Gy and 1.0 Gy. The dependence of the nature of the changes in the activity of enzymes of energy metabolism of the phylogenetic age of the crust.
OXIDIZING UPDATING OF PROTEINS AND CHANGE OF ACTIVITY CATHEPSIN L RATS SPLEEN IN THE CONDITIONS OF MODELING DEFICIENCY OF NITRIC OXIDE SYNTHESIS
Authors: Abalenihina J V , Fomina M A , Isakov S A
Published: October 2016

Influence inhibitor synthesis NO-synthase on activity cathepsin L and oxidising updating of proteins in a spleen of rats is studied. It is established that in the conditions deficiency of nitrogen oxide synthesis the quantity aldehyde-dinitrofenilgidrazons of neutral and basic character decreases, the quantity keton-dinitrofenilgidrazons neutral character with one-stage increase in activity cathepsin L thus increases.
L-NORVALIN AND ISCHEMICAL PRECONDITIONING ACTION MECHANISMS ANALYSIS AT LIVER ISCHEMIA/REPERFUSION
Authors: Pokrovsky M V , Lopatin D V , Alehin S A , Kolmykov D I , Ivanova L V , Lucenko V D , Speransky S L , Suhoterin I V
Published: October 2016

In this article ischemical preconditioning and L-norvalin efficacy and mechanisms of action pharmacological analysis at liver experimental ischemia/reperfusion were made. During investigation ischemical preconditioning high effectiveness totally wasn’t blocked by glibenclamide showed. L-norvaline also showed marked hepatoprotective effect abolished by glibenclamide just partly.
INVESTIGATION OF INSULIN-, GLUCAGON-, SOMATOSTATIN-POSITIV CELLS LOCALIZATION IN THE LANGERHANS’ ISLENDS IN DIFFERENT PERIODS OF BIOCYCLE OF ANURA
Authors: Savelieva E S
Published: October 2016

Article deals to immunohistochemistry investigation of endocrine cells (insulin, glucagon, somatostatin) localization in the amphibian Langerhans’ islends in different periods of biocycle. In the investigation were used pancreatic glands of three amphibian species (Pipa Pipa L. 1758, Rana temporaria, L. 1758, Rana ridibunda, Pallas 1771). Study showed relationship of quantity of different endocrine cells types is not equal depending on biocycle’s period.
STANDARDIZATION AS A BASE FOR MEDICAL CARE IMPROVEMENT IN THE RYAZAN REGION
Authors: Manukhina E V , Artemyeva G B
Published: October 2016

The goal of the research paper is to estimate the influence of the promoted medical standards on the process of medical aid rendering in hospitals. It’s indicated that medical care standards enable to plan the resources and medical care capacity more effectively within the bounds of the compulsory medical insurance territorial program. Medical standards promotion leads to methods improvement of medical aid quality management. Resource provisioning of standards increases realizing pharmacotherapy effectiveness and furthers medical personnel motivation to improve a medical care quality and reach results. Moreover, medical aid standards promotion is directed to patients and doctors’ rights protection in the solutions of conflict situations.
THE CONDITION OF CHILDREN AND TEENAGERS NUTRITION ORGANIZATION IN RYAZAN REGION: REGIONAL EXPERIENCE AND PROSPECTS
Authors: Grevtsova E A , Safonkin S V
Published: October 2016

The problems of organization improvement of hight-quality and safe nutrition of pupils are solved through a long-term focused programme “Ryazan region Education Development in 20102014”. In 2011 84, 3% of Ryazan region pupils got hot meals. There are different canteens in 96, 7% of institutions. In 2011 the region was a participant of experimental project on organization improvement of pupiles’ nutrition. The project covers 21 Ryazan schools (14735 pupiles) and Municipial institution “Baby food”. Health protection and education authorities work very hard on health food promotion.
MEDICAL AND SOCIAL CHARACTERISTICS OF PENSIONERS LIVING AT HOME AND IN THE BOARDING HOUSE
Authors: Shigabutdinov A F
Published: October 2016

The article presents a comparative medico-social characteristics of pensioners living at home and in the boarding house. The analysis of age structure, education level, place of work and specialty until retirement, the presence of contacts with occupational hazards was carried out. We studied the living conditions, financial status, the presence of disability, the reasons for staying at a boarding house, an assessment of relations with relatives.
MEDICAL DEMOGRAPHICAL CHARACTERISTICS OF THE CHILDREN INJURED IN THE ROAD TRAFFIC ACCIDENTS IN VORONEZH REGION
Authors: Dedov A A , Tsomaya V V , Ilyshina L N
Published: October 2016

The yearly analysis of the main components of the structure and causes of the road traffic traumatism of the children of the preschool age and the primary school age is represented in this article. The article contains the enumeration of the age rates and frequency of traumas at road traffic accidents, conclusions and practical guidelines of the specialization of the noted facts.
ANALYSIS OF ANTERIOR RESECTION OF THE RECTUM RESULTS
Authors: Semionkin E I , Khubezov D A , Kulikov E P , Trushin S N , Ogoreltsev A Yu , Lukanin R V , Yudina E A
Published: October 2016

The analysis of treatment of 154 patients with rectal cancer after resection of the rectum in specialized department was done. Safety of machine stitch in rectal cancer surgery and reasonability of preventive colostomy especially in low rectal cancer localization were showed.
INFLUENCE FACTORS SPECIFIC TO MILITARY SERVICE PERFORMANCE COMPONENT OF THE BODY MASS YOUTH
Authors: Shpakova N A , Andriychuk V M , Guminskiy Y I
Published: October 2016

Identification of the possible impact of specific factors on the military service component composition of body weight in a population of healthy young men serving in the armed forces.
ROLE OF PROINFLAMMATORY CYTOKINES IN CHRONIC HEART FAILURE
Authors: Osipova O A , Suyazova S B , Vlasenko M A , Godlevskaya O M
Published: October 2016

Accumulating evidence indicates that cytokines play an important role in the pathogenesis of chronic heart failure. The review considers the participation of proinflammatory cytokines (factors-necroses-tumors-α, interleukin 1β and interleukin 6) in the pathophysiological processes of congestive heart failure, as well as the influence of proinflammatory cytokines on cardiac contractility, hypertrophy and remodeling of the left ventricle of the heart, apoptotic, and fibrotic processes.
ROLE OF MATRIX METALLOPROTEINASES IN THE PATHOGENESIS OF PRIMARY OPEN-ANGLE GLAUCOMA
Authors: Sokolov V A , Levanova O N
Published: October 2016

Matrix metalloproteinases (MMPs) - a family of enzymes, which convert extracellular matrix. Proved the role of MMPs in apoptosis of retinal ganglion cells, tissues remodulition the optic nerve and the change in the form of lattice plate with POAG. MMPs are involved in violations of blood aqueous barrier and the regulation of intraocular fluid. Many papers have focused on the role of these enzymes in the filter pad with scarring antiglaucomatous operations. The study of MMPs offers the prospect of early diagnosis and targeted therapy of POAG pathogenesis.
DYNAMICS OF ADAPTIVE MECHANISMS SUCH AS THE OPTIMIZATION CRITERIA MAGNETIC INTERFERENCE
Authors: Bulatetsky S V , Byalovsky Yu Yu , Glushkova E P
Published: October 2016

This article has studied the local action of the alternating magnetic field on the nonspecific mechanisms of human adaptation. It is shown that the body’s response to the electromagnetic effect is a complex phenomenon system, including mechanisms at various levels and has its own functional organization. Parameters of local influences AMF must be optimized based on the dynamics of adaptive mechanisms: the spatio-temporal local magnetic therapy must maintain a minimum activation of stress mechanisms and implement the most include stress-limiting mechanisms.
TO THE MECHANISM OF ACTION OF NEW ANTIHYPOXIC COMPLEX COMPOUND OF ASCORBIC ACID
Authors: Novikov V E , Markova E O , Parfenov E A
Published: October 2016

In the experiment on rats a new derivative of ascorbic acid with antihypoxic activity was learned. It is shown that a dose of 100 mg / kg in normoxia and after exposure to acute hypoxia, it reduces the activity of free radical oxidation, has no effect on the hemogram, but leads to a significant reduction of ALT, AST, alkaline phosphatase, LDG, the level of uric acid and total protein after acute hypoxia, which is of some importance in its hypoxic effect.
STUDYING OF ANTIATHEROGENEOUS PROPERTIES OF PREPARATIONS FROM THE BIOMASS OF GINSENG AND POLISCIAS FILICIFOLIA BAILET CELLULAR CULTURE
Authors: Ryabkov A N , Slepnev A A
Published: October 2016

This article is devoted to an assessment of degree of expressiveness of antiatherogenous properties of preparations from the biomass of ginseng and poliscias filicifolia bailey cellular culture. The experiments were performed on rabbits, kept for a month on the strictly antioksidantless diet and on the hypodynamy immobilization condition. An analysis of the biochemical parameters of serum lipid spectrum and intensity of lipid peroxidation in the tissue of the aorta in preventive and therapeutic uses of comparable compaunds indicates a rather pronounced antiatherogenic properties of drugs of Araliaceae plant biomass, especially poliscias fiicifolia.
DYNAMICS AND TRENDS REPRODUCTIVE LOSSES IN THE RYAZAN REGION
Authors: Medvedeva O V , Petrova E I
Published: October 2016

The paper presents an analysis of reproductive losses, which, in addition to part of the reproductive potential and reproductive behavior, is one of the most important characteristics of reproductive health. The main directions of improving reproductive health can only be realized by improving the quality of basic obstetric and perinatal care.
PROINFLAMMATORY CYTOKINES AND THEIR ROLE IN THE DEVELOPMENT OF CARDIOVASCULAR COMPLICATIONS IN PATIENTS WITH HYPOTHYROIDISM
Authors: Vernigorodsky V S , Fetisova N M , Vernigorodskaya M V
Published: October 2016

The study of interleukin-6 and C-reactive protein in 101 patients with hypothyroidism revealed a close relationship between metabolic, proinflammatory factors and the state of blood vessels in patients with hypothyroidism (p 0,05) compared to healthy individuals. Formation of pro-inflammatory state is a risk factor for vascular intimal lesions in patients with hypothyroidism, especially with the idiopathic form of it.
HEART RATE VARIABILITY IN PATIENTS WITH ACUTE CORONARY SYNDROME WITH ST-SEGMENT ELEVATION ON THE BACKGROUND THROMBOLYTIC THERAPY
Authors: Girivenko A I , Nizov A A
Published: October 2016

The heart rate variability in patients with acute coronary syndrome with ST-segment elevation in the ECG and their changes against thrombolytic therapy depending on its performance. Shows the evolution of heart rate variability depending on the efficacy of thrombolytic therapy.
THE INFRADIAN RHYTHMS OF CORTISOL AND THYROID HORMONES AT WOMAN OF REPRODUCTIVE AGE
Authors: Diatroptov M E , Simonova E Yu , Diatroptova M A
Published: October 2016

The levels of cortisol, free and total thyroxin in the serum of the 6 th woman of 23-33 aged old in the follicular phase of menstrual cycle was studied by ELISA method. The cortisol level was fluctuated during the 4-day period. The levels of free and total thyroxin were changed in the 3-day period. Both fluctuations were synchronous in all studied woman. Revealed biological rhythms of glucocorticoids and thyroid hormones should be taken into account when hormonal and immunologic status of healthy woman is researched and corrective methods of pathologic states are developed.
ASPECTS OF Ethico-deontological AND LEGAL ASPECTS OF RENDERING the dermatovenerological help to the population
Authors: Zhiltsova E E
Published: October 2016

The paper presents the results of a poll of 578 patients who are residents of the Ryazan region who applied for dermatovenerological help. The issues of patient satisfaction by medical help obtained and the conditions of its reception as well as the attitude of medical workers are considered. The ethical, deontological and legal problems of rendering dermatovenerological help to the population are analyzed.
INTERACTION OF COMPOSITE MESH Implanted With peritoneum abdominoplasty
Authors: Vorovskii O O
Published: October 2016

An experimental study on 10 outbred dogs, of which 6 (main group) into the peritoneal cavity of a polypropylene mesh was implanted helium-coated cellulose. In all cases, the implants are contacted with the loops of the small intestine. Three months later by histological examination of a strong link ("rooting") polypropylene mesh implanted with adipose tissue of the greater omentum dog in the absence of alterative changes in the implant, and a helium coating of cellulose prevented the formation of adhesions with the surrounding organs of the abdominal cavity.
IMPORTANCE OF MARKERS OF THE PROLIFERATION AND APOPTOSIS FOR OVARIAN BODERLINE TUMOURS
Authors: Vinogradov I I , Zavalishina L E , Andreeva Yu Yu , Akhidova E V , Volpina O M , Volkova T D , Koroev D O
Published: October 2016

For today, one of actual problems in gynecologic pathology are borderline tumours of the ovary to which frame of a case rate the high specific gravity is compounded by women of reproductive age. Thereupon often there is a question about safety treatment methods, that dictates necessity of an assessment of risk of development of recurrence of disease. In present article attempt to define prognostic importance of markers of proliferative activity (ki67, cyclin D1, p21), and pro-and antiapoptotic markers (p53, bax, bcl-2, survivin) for definition potentially an aggressive behavior of ovarian borderline tumour.
COMPARATIVE ANALYSIS OF ELEMENT, CARBOHYDRATE AND AMINO ACID COMPOSITION OF VALERIANA OFFICINALIS UNDERGROUND ORGANS
Authors: Fursa N S , Karavanova E N
Published: October 2016

The results of determination of analysis of 6 macro- and 54 microelements, 3 free and 4 bound sugars, 8 irreplaceable and 11 replaceable amino acids content in Valeriana officinalis rhizomes, roots and rhizomes with roots were analyzed.
MODERN ASPECTS OF ETIOLOGY AND PATHOGENESIS OF DISEASES OF PARODONT
Authors: Fuks E I , Kareva U A , Galizina O A , Tabolina E S
Published: October 2016

The article is devoted to the review of the modern literary data regarding etiology and pathogenesis of diseases of parodont. Many general and local factors take part in development and progression of inflammatory diseases of parodont. Role of chronic odontogenic infection in development of somatic pathology is described in this article.
LIFE SCRIPTS IN VIEW OF THE FUNCTIONAL SYSTEMS THEORY BY P.K. ANOHIN (In search of common points of psychology, psychiatry, and psychophysiology)
Authors: Chustov D I , Fedotov M A , Novikov S A
Published: October 2016

The article represents the review of contemporary understanding of life scripts in view of the functional systems theory by P.K. Anohin. The concepts of the action result acceptor and script decision as the central backbone factor are compared. From the point of view of relativistic theories of psyche the process of metalization of narrative life script is described. As exemplified by autobiographic stories and contemporary scientific investigations, psychological aspects of “anticipatory reflection” are shown.
DEVELOPMENT OF RULES OF THE RUSSIAN PENAL LEGISLATION ON RESPONSIBILITY OF DRUNK CRIMES
Authors: Peremolotova L Yu , Shilov A I
Published: October 2016

The article deals with the genesis of penal legislation in Russia concerning crimes committed in a state of alcoholic intoxication in XX-XXI centuries. Based on the criminological, social and legal analyses of anti-alcohol policy the authors suggest that in the beginning of XXI century alcoholic situation in Russia is characterized by increase in the issue urgency and further expansion of alcohol-related crimes.
MORPHOLOGICAL CHANGES OF THE TRACHEA, BRONCHI AND LUNGS OF MICE WITH LONG EXPOSURE OF CHEMICALS PRESENT IN THE AIRSPACE OF MANNED SPACECRAFT
Authors: Oganesyan M V , Ponomarenko E A
Published: October 2016

It was conducted the morphological study of chronic exposure MPC of chemicals (acetone, acetaldehyde, ethanol) of airspace of the spacecraft on the trachea, bronchi and lungs within 70 days in male mice line of F1 (CBA x C57Bl6). At morphometric study at experimental group of mice are revealed foci of fibrosis and hyperplasia of lymphoid tissue in the wall of the trachea and bronchi, in the lungs are marked elevation of lymphoid accumulations in the wall of the main and lobar bronchi and around blood vessels. The mechanisms of development of pathological changes in the respiratory system under the influence of small doses of chemicals are discussed.
GRAN INFORMATION SYSTEM OF ORGANIZATION OF MENTAL BRAIN
Authors: Sudakov K V
Published: October 2016

In the article the information processes involved in the activities of the functional systems of the body. Formulated ideas about the information needs and their equivalents satisfaction. It is shown that the evaluation of information in the brain is on the morphological and functional architectonic acceptors results of the action functional systems. Acceptors on the results of the action are built sistemokvants information that admission to them afferent feedback from behavioral and autonomic sistemokvants, monitor their effectiveness. The dominant motivation, situational and launchers (conditioned reflex) removed the incentives of Advanced Information sistemokvants acceptor of action results. The article reveals some genetic and biological properties of individually purchased motivations and accompanying information equivalents sistemokvants acceptor of action results, as well as forming the basis of this dynamic holographic images. It is suggested that the holographic images acceptor action results represent specific integration of molecular and atomic vibrations occurring in the form of neurons, glial cells and cerebral fluid. It is shown that the logic of building information sistemokvantovs acceptors results of action allows a system approach to explain the processes of consciousness and thinking.
THE SYSTEM ORGANISATION OF SUBJECTIVE PROCESSES IN A BRAIN
Authors: Yumatov E A
Published: October 2016

Subjective state of the person can be registered distantly objectively. Existence of "a psychogenic physical field» of a brain which cannot be at the lifeless nature is stated. Interaction of neurophysiological and subjective processes in the system organization of purposeful behaviour is described. The paradigm, considering possibility of existence unique for a live brain of the physical phenomena, and their role in an origin of a subjective state are offered.
IMPACT OF CHRONIC HEART FAILURE IN THE MANIFESTATION OF SEIZURE READINESS AND ITS ASSOCIATION WITH RESISTANCE TO HYPOXIA
Authors: Mamalyga M L
Published: October 2016

Chronic heart failure (CHF) modulates the activity of monoaminergic (MA-) systems and increases seizure readiness, and the severity of seizure depends on the individual resistance of the organism to oxygen deficiency. Increasing seizure readiness, and reduction of monoamines in postictal period at high and low resistance of the animals with CHF gives reason to believe that the activity of MA-ergic system may be a factor limiting the implementation of compensatory capacities in heart failure. Postictal period against the background of heart failure is characterized by the marked reduction in aminergic tone in the brain regions studied low resistance of the animals that are likely to acquire pathogenetic importance and can be the basis for the occurrence of repeated seizures.
MORPHOLOGY OF THE INNER RELIEF OF CHICK EMBRYONIC VENTRICULAR MYOCARDIUM AT 6-8 DAY INCUBATION
Authors: Goodlett T A , Tverdokhleb I V
Published: October 2016

Aim of this work was to create three-dimensional computer models of сhick embryonic heart at 6-8 day incubation followed by a comparative assessment of ventricular inner relief. In the present study, we reconstructed and morphometrically analyzed the heart staged chick embryos with the aid of computer software and compared their structures for the further assay. We show that development of the inner relief is implemented in different ways in left and right ventricles.
ANALYSIS OF PERINATAL CENTER IN A MULTILEVEL SYSTEM OF HEALTH CARE FOR WOMEN DURING PREGNANCY, CHILDBIRTH AND THE POSTPARTUM PERIOD (for example, the Ryazan region)
Authors: Petrova E I , Medvedeva O V
Published: October 2016

The paper presents an analysis of the Ryazan regional perinatal center in the development and improvement of obstetric care, introduction to practical health of modern medical technology. Given the specifics of the particular attention paid to the problem of providing highly specialized medical care for women of reproductive age.
THE HEALTH STATUS OF SOCIALLY VULNERABLE POPULATION GROUPS
Authors: Chirkov V A , Breusov A V
Published: October 2016

In the course of the research were identified and reviewed a causal link between the main factors (age, sex, education level, etc.) and the health status of socially vulnerable groups of the population of the city of Moscow. It is established, that consider themselves healthy and practically healthy 68% of the patients themselves as 10%, are not interested in their health 22% of respondents. The share of persons who consider themselves sick, increases with age in an exponential curve. The tendency of the revaluation of the level of health among people with chronic diseases, which testifies to the shortcomings in the prevention work of primary health care services.
PRIORITY question OF occupational hygiene AT THE ENTERPRISES OF THE SECONDARY LEAD
Authors: Chudinin N V , Kiryushin V A
Published: October 2016

Conditions of work in the secondary lead metallurgy is largely related to the technology of raw materials processing. Complexes sanitary-and-hygienic assessment of the lead recycling technologies allows seriously and purposefully develop preventive activities aimed at the improvement of working conditions and health of workers.
Phenotypic markers of connective tissue dysplasia in primary spontaneous pneumothorax
Authors: Miheev A V , Trushin S N , Baskevich M A
Published: October 2016

The paper presents the results of a survey of 21 patients with primary spontaneous pneumothorax using valuation techniques phenotypic criteria of connective tissue dysplasia.
Prognostic significance of degree histologically malignant ductal pancreatic adenocarcinoma
Authors: Filippova E M , Pakhlim O V , Chekmareva I A , Kochatkov A V , Lebedeva A N , Kravchenko E V
Published: October 2016

The article presents the results of a study of 47 patients (22 males and 25 females) PAK prostate treated at Institute of Surgery. A.V. Vishnevsky from 2005 to 2012. The age of patients ranged from 47 to 76 years, mean age was 60 years. In 24 patients at the time of surgery was diagnosed IIb (pT2- 3, N1) tumor stage, 19 - IIa (pT2-3, N0), have 3 -III (pT4), from 1 - Ib (pT2, N0). In 27 observations revealed metastases to regional lymph nodes (N1). Staging was performed according to the revision of the International Classification of 7 TNM (UICC, 2010). The results also show that such clinical and morphological characteristics as gender, patient age, stage and tumor size did not affect the postoperative survival. No significant correlation between patient survival and tumor grade (grade), determined by the degree of differentiation, as recommended by WHO. In contrast, when using the Gleason system, which takes into account not only the most abundant component in the tumor, but also the second most common, obtained a significant correlation with postoperative survival rates, making this a promising grading system for use in the diagnosis of ductal adenocarcinoma of the pancreas.
Morphologic and morphometric description of vascular component part (vessels of microcirculatory net and cell population around them) of communication systems in the cervical carcinona tissues
Authors: Bekhtereva I A
Published: October 2016

The data of morphometric and morphologic study of cervical carcinoma is cited in this article. Morphometric study of cellular population revealed significant increase of fibroblasts, lymphocytes, plasmocytes and macrophages around arteriola, capillaries, venula in the tumour's tissues in comparison with contralateral region. The number of lymphocytes, plasmocytes and granulocytic leucocytes around venula and capillaries in the tumour's region was growing as compared with contralateral region. Fibrocytes' and macrophages' population and parenchymal cells were the most stable.
Principles of modern treatment of multiple sclerosis (at the example of Ryazan region)
Authors: Lorim L V , Dzhaparalieva N T , Mikheeva L M
Published: October 2016

Treatment of multiple sclerosis (MS) is one of the most challenging problems of the modern practice of neurology. Due to the fact that the etiology of the disease is still un-clear,and it is impossible for prevention and etiological therapy. At the same time, the active introduction of drugs in the clinical practice of disease-modifying therapy for multiple sclerosis (DMT), earlier was kind of impossible but at present days it is one the of the difficult disease to treat. Now a days, immunomodulatory drugs are the drug of choice for thepathogenetic treatment of MS. The paper presents the main factors determining the current approaches to the treatment of MS. Based on the literature data and the results of our observations are given basic regimen in different stages of the disease depending on the type of disease in MS patients at Ryazan region.
Morphological characteristics and features in sertoli cell ultrastructure experimental varicocele
Authors: Pivtorak V I , Smiyukha O A
Published: October 2016

Established anatomical morphometric characteristics of Sertoli cells in the simulation of varicocele and after treatment. After modeling varicocele perimeter and diameter of the cells and their nuclei was significantly decreased with increasing periods of varicocele. After undergoing surgery to Ivanissevich increased performance area, perimeter and diameter of Sertoli cells and their nuclei, but not enough to normalize their function. Forming operation between veins microvascular anastomosis using the method gives better results Sertoli cell regeneration compared to traditional obstructive operations because it normalizes the nuclear-cytoplasmic ratio and thereby creating more favorable conditions for the restoration of spermatogenic function.
Topography of thymus humans in early fetal period of its development
Authors: Galeeva E N , Zheleznov L M
Published: October 2016

Сongenital malformations of the thymus, the interpretation of which is difficult when ultrasound study of the chest cavity in the early stages of prenatal ontogenesis often put the question of choosing one of the planes 3 standard directions. Compliance plane images structures, ultrasound and sectional slices is key for conducting work in this direction. The study was 60 human fetuses obtained at artificial abortion for social reasons in age from 16 to 18 weeks ’ gestation. New data have been obtained outside of organ topography of the thymus man in the early fetal period of ontogenesis, depending on the level and the slice of the torso of the fetus. Research data complement the information on the morphology of the thymus fetus and are basic in conducting ultrasound examination.
LYMPHOPROLIFERATIVE DISEASES COMPLICATED BY OPPORTUNISTIC INFECTIONS
Authors: Bulieva N B
Published: October 2016

Opportunistic infections often complicate the course of lymphoproliferative disorders. Study of changes of the immune status of patients with lymphoproliferative diseases complicated by opportunistic infection, it is an urgent problem.
Analysis of the russian wholesale market of eye drops for 2006 - 1-3 quarter 2012
Authors: Arustamova A A , Pokrovsky M V , Shabelnikova A S , Kashuba A S
Published: October 2016

This article contains analysis of the Russian wholesale market of eye drops for 2006 - 1-3 quarter 2012 using pharmacoeconomic and economic-mathematical methods of analysis. The objects of study were the wholesale market of eye drops registered in the Russian Federation, during the study time period, the official source of information - the Register of medicines in Russia (2012). The analysis for 2006 - 1-3 quarter 2012 found rising wholesale eye drops by a robust demand.
Monitoring of air quality in the city
Authors: Lyapkalo A A , Dementiev A A , Tsurgan A M
Published: October 2016

In the article there is outcome analysis of air quality monitoring in Ryazan by the data of stationary sites. Daily and season dynamics of the average content of carbon oxide and nitrogen dioxide in the air in the warm and cold seasons are investigated and analyzed by the dispenser analysis. Periods characterized by the highest average concentrations of pollutants in the air are revealed. The relation between the air pollution level and the motor transport emissions is revealed and analyzed. Direct correlation dependence between air pollution by carbon oxide and nitrogen dioxide and the motor transport emissions in the cold season is detected.
Endoscopic ultrasound role of research in the determination of the possibility endo-biliary stenting in patients with neoplastic lesions periampulyary zone
Authors: Chabounine A V , Tavobilov M M
Published: October 2016

The article presents the results of treatment of 249 patients with neoplastic lesions of the head of the pancreas complicated by obstructive jaundice secondary to severe , were treated at the surgical clinics GKB after SP Botkin Clinical Hospital № 1 and the NI Pirogov from 2008 to 2012. The ratio of male to female ratio was 1:1.7 , respectively (155 and 194). Mean age was 65,8 ± 0,7 years. It is shown that the use of the algorithm instrumental diagnosis in patients with obstructive jaundice , including EndoUZI allows a differentiated approach to the choice of biliary decompression in patients with obstructive jaundice of tumorous lesions of the pancreatic head.
Using of combination of the dermal matrix with allogeneic cells for treatment of extensive traumatic wounds
Authors: Khubutia M S , Pokhitonov D Y , Borovkova N V , Filippov O P , Kljukvin I Y , Khvatov V B , Ponomarev I N , Shugay S V , Andreev Y V
Published: October 2016

The article presents a comparative analysis of the efficiency of allogeneic progenitor cells with different biological carriers for preparation of extensive traumatic wounds to autodermoplasty. As carriers were selected dermal matrix and collagen first type of human. The article presents the results of treatment of 43 patients. Based on these data the effectiveness of the combination of allogeneic progenitor cells and dermal matrix is demonstrated. This combination reduces the incidence of purulent complications and reduce the time of prepare wounds for autodermoplasty.
EXPERIENCE OF PERMACOL USE IN EXPERIMENT AND IN CLINICS
Authors: Khubezov D A , Trushin S N , Ogoreltsev A Y , Mnihovich M V , Puchkov D K
Published: October 2016

Our experience in use of biologic implant Permacol is shown in the article. An experiment on rabbits was made to compare biologic characteristics of implants Prolen and Permacol, in the result of which Permacol proved good biocompatibility and high resistance to tissular enzymes and infection. In the faculty surgery clinic based on the coloproctological department of Ryazan Regional Clinical Hospital Permacol was used twice: for replacement of anterior abdominal wall defect and for replacement of pelvic floor defect after extended operations on oncological patients. Both cases we had good results. Our experience allows to recommend use of Permacol not in open wound, but cover the prosthesis with skin.
Modern technologies of treatment of patients with umbilical hernia
Authors: Muraviev S Y , Fedoseev A V , Avdeev S S , Gazuani A I , Strekalov E V
Published: October 2016

This article describes the results of research of an umbilical ring biomechanics in patients with umbilical hernia of the small and medium sizes. During work constancy of its form and the sizes is established that, according to the authors, pathogenetic justified of the use of prosthetic techniques. Proposed and developed by authors the method of intraumbilical preperitoneal prosthetics for surgical treatment of patients with this pathologies.
Innovative technologies in rehabilitation treatment of patients with lumbar osteochondrosis
Authors: Sokolov A V , Svintsova S E , Antonovich M N
Published: October 2016

In the work we presented the indicators usage of the the organism functional reserves for the objective estimation of the clinical functional conditions peculiarities and the results of patients treatment with lumbar osteochondrosis at the level of sanatorium-and-spa treatment. 120 patients were involved into the investigation. We proved that usage of “Detensor”- therapy improves the results of the complex sanatorium-and-spa treatment of the given category of patients. It allows achieving quicker regress of clinical manifestations of the disease and more expressed increase of the functional reserves of the organism.
The influence of great nettle polysaccharide on physical activity of animals, processes of phagocytosis and resistance of erythrocyte membranes
Authors: Kalinkina O V , Sichev I A
Published: October 2016

Polysaccharide complex is excreted from great nettle, qualitative and quantitative monosaccharide composition is determined, its influence on physical activity, processes of phagocytosis, osmotic, thermic and peroxide resistance of erythrocyte membranes is studied.
Role arteriovenous fistula in femoral-tibial bypass surgery
Authors: Pokrovsky A V , Yahontov D I
Published: October 2016

The article provides an overview of world literature data on existing techniques to improve the results of distal reconstructions by applying arteriovenous fistulas in the formation of the distal anastomosis in patients with obliterating diseases of the lower extremities. The data on the benefits of worldwide research of a method depending on the type, shape and location of venous cuffs or patches. Examined the immediate and long-term outcomes with the use of these techniques, data analysis, comparative application autovenous grafts, shunts combined with the use of arteriovenous fistulas in the formation of distal anastomosis and PTFE prostheses in position below the gap of the knee.
Developmental features of liver and spleen blood capillaries of human embryos and fetuses under the effect of anthropogenic factors of chemical production on mother
Authors: Ponomarev B L , Obuhova L E , Vysoski U A , Barsukova N I , Cherdantseva T M
Published: October 2016

The subjects of the electronic microscopy exploration are the phases of human liver and spleen blood capillary formation during the early stages of pregnancy under the effect of the anthropogenic on hepatic and splenic cell euchromatin of embryos and fetuses disturbances of angio-genesis identified.
Comparative evaluation of lipid peroxidation and antioksidant system in patient concomitant diseases acne gastrointestinal
Authors: Golovach N A , Ermoshina N P , Isakov S A
Published: October 2016

Lipid peroxidation (LPO), antioxidant system (AOS), of patients with acne without concomitant diseases and disorders of the digestive system during treatment with using of bee products were studied. Patients with acne increased free radical activity on the background of oppression antioxidant defense deteriorated, but in patients with disorders of the gastrointestinal tract the data correlates were more expressed. The processes were stabilized after the using into the complex therapy of bee products.
Research of endothelio-and cardioprotective effects of enalapril, lozartan and amlodipin at modelling hyperhomocystein induced endothelial dysfunction
Authors: Korokin M V , Pokrovskii M V , Kochkarov V I , Gudyrev O S , Pokrovskaia T G , Korokina L V , Polyanskaya O S
Published: October 2016

On laboratory animals we investigate endothelio- and cardioprotective effects of enalapril, lozartan and amlodipine at modeling hyperhomocystein induced endothelial dysfunction. It is established that use of ACE inhibitors, blockers of ATI of receptors and calcium channels blockers at the general, expressed endothelio-and cardioprotective action, allows to correct only a number of indicators of functioning an vascular endothelium and cardiovascular system as a whole.
Influence of preparation from the biomass of ginseng on biochemical parameters of erythrocytes at experimental hypoxia
Authors: Ryabkov A N
Published: October 2016

In the work the experimental research of features of dynamics of a complex biochemical parameters of erythrocytes on laboratory animals with a modelled acute hypoxic hypoxia after application of preparation from biomass of ginseng is conducted. Experiments were carried out on rats with acute hypoxic hypoxia which was modelled in a pressure chamber. The statistical analysis of changes of biochemical parameters testifies about rather expressed antihypoxic effect of a preparation from biomass of ginseng.
Associations of acrocentric chromosomes in small-for-date newborns from different ecological zones of Precarpathia
Authors: Kocherha Z R
Published: October 2016

The analysis of umbilical cord blood of 174 healthy newborns and 152 small-for-date newborns from different ecological districts of Ivano-Frankovsk region has been performed in order to evaluate the rate of associations of acrocentric chromosomes in neonates from Precarpathian Ukraine. The rate of associations of acrocentric chromosomes in newborns with intra-uterine growth retardation syndrome from the investigated ecological zones was 3,91; 3,0 and 2,07% higher than in healthy newborns from zones of ecological comfort, chemically polluted territories and zones of radiation contamination consequently. The analysis of the average number of associations of acrocentric chromosomes within one cell showed the tendency to the increase of the actual rate in small-for-date newborns from all the investigated zones as compared to its rate in healthy newborns.
Diagnosis modified parathyroid the treatment of primary hyperparathyroidism interstitial laser photocoagulation
Authors: Pamputis S N , Alexandrov Yu Konstantinovich , Patrunov Yu Nikolaevich , Lopatnikova E N
Published: October 2016

Interstitial laser photocoagulation is an advanced minimally invasive treatment for primary hyperparathyroidism. The basis of its use is accurate topical diagnosis changed parathyroid glands (OSCHZH). Proposed fine-needle aspiration biopsy OSCHZH modified with a certain level of parathyroid hormone (PTH) in the wash of the needle (FNAB / PTH). The method is reliable, informative and safe. It is shown that TAPB / PTH allows an accurate verification of modified OSCHZH thereby ensure that minimally invasive treatment of primary hyperparathyroidism without traditional surgery.
The peculiarities of intermitochondrial contacts during ontogenetic formation of mitochondria network in normal and under hypoxic damage of cardiogenesis
Authors: Ivanchenko M V , Tverdokhleb I V
Published: October 2016

The aim of this work was to determine the formation of intermitochondrial contacts during ontogenesis of mitochondrial reticulum and to evaluate the degree of mitochondria associations under the influence of prenatal hypoxia. In the present study, we analyzed that in normal conditions the number of intermitochondrial contacts was different in areas of the cell and changed to the stages of ontogeny. Influence of intrauterine hypoxia and oxidative stress leads to mitochondrial reactions that affects to the formation between organelles intermitochondrial contacts in the sub-sarcolemmal, intermyoflbrillar and paranuclear regions of ventricle cardiomyocytes.
INTRAVENOUS LASERTHERAPY AND INTERVAL NORMOBARIC HYPOXYTHERAPY EFFECTIVENESS IN ASTHMA AND COMORBID ESSENTIAL HYPERTENSION COMPLEX THERAPY
Authors: Uryasev O M , Isaeva I A
Published: October 2016

82 patients with asthma and comorbid essential hypertension were examined with the aim of intravenous lasertherapy and interval normobaric hypoxytherapy evaluation in combined pathology complex therapy. Physical factors including in therapy of patients with this combined pathology definitely improves condition and functional indexes; positive dynamics expression also might help drugs dose decreasing. It allows recommend intravenous lasertherapy and interval normobaric hypoxytherapy adding to basic medicinal therapy.
The form and the disposition of the lower border of the maxillary sinus at the physiological, mesial and distal occlusion of dentition
Authors: Nabatchikova L P , Horoshilkina F Ya , Arman Chobanyan , Armine Chobanyan
Published: October 2016

We have studied 99 lateral teleroentgenograms of the scull made in patients aged 20 to 45. There were 48 patients with physiological occlusion of dentition, 36 patients with distal occlusion and 15 patients with mesial occlusion of dentition. We have identified four basic forms of the lower boundary of the maxillary sinus and 3 types of its vertical distance from the basis of maxilla (line ANS-PNS) in the portions corresponding to the position of the premolars’ and molars’ root tips. We have compared the frequency of the location of the posterior teeth’s root tips above the lower boundary of the sinus for various types of dental occlusion. This analysis is important for forecasting outcomes of orthodontic mesial/distal movement of posterior teeth, as well as for replacement of defects of the upper denture by implant-supported prostheses.
THE METHOD OF QUANTITATIVE EVALUATION OF SOME PARA-AMINOPHENOL DERIVATIVES IB PHARMACEUTICAL AND CHEMICO-TOXICOLOGICAL INVESTIGATIONS
Authors: Chekulaeva G Yu , Gromova Z F
Published: October 2016

The materials on the development of analytical methods for paracetamol using a spectrometric technique in the pharmaceutical substance, medicinal forms and biological liquids are presented in the paper.
Comparative morphological study of spinal cord of siamese twins
Authors: Shkolnikov V S , Guminskiy U U , Zherebyatyeva S R
Published: October 2016

Considering the rarity of occurrence of such anomalies of human development, like siamese twins, and a few reports of a descriptive nature in the available literature that would have dealt with these studies, we performed anatomical and histological, histochemical and morphometric study of spinal cord siamese twins (thoracopagus) in a comparative perspective: right - left. Found that significant differences in the structures of the spinal cord cytoarchitectonics the left and right of the fetus thoracopagus person we have not identified. However, slight differences in morphometric parameters observed at the level of the cervical and lumbosacral bulges. The results, in our view, not only complement the knowledge in human teratology, but in neuroanatomy as a whole.
THE EFFECT OF SPECIFIC PHARMACOTHERAPY ON THE DEGREE OF OXIDATIVE MODIFICATION OF PROTEINS AND LIPIDS IN THE BLOOD PLASMA OF PATIENTS WITH KNEE OSTEOARTHRITIS
Authors: Mescheryakova M G , Trilis Ya G , Kirillova N V , Mukhin I A
Published: October 2016

Knee osteoarthritis is followed by the intensification of free radical oxidation of proteins and lipids in the blood plasma of patients. Specific pharmacotherapy leads to a significant reduction in the content of carbonyl groups, aliphatic aldehyde groups and malondialdehyde in the tested samples, and to an increase in the total protein content up to normal physiological values in half of the treated patients. The results of the study allow us to recommend the use of these indicators in laboratory diagnostics for indepth study of the degenerative dystrophic process in the knee joint, as well as to monitor the progress of therapy and to evaluate the effectiveness of therapeutic interventions.
STRUCTURAL ORGANIZATION OF THE SPECTRAL PATTERNS OF EEG IN THE PROCESS OF LEARNING A FOREIN LANGUAGE AND ITS RELATIONSHIP WITH THE ACOUSTIC SPEECH PROSODY
Authors: Deriagina L E , Khokhlova L A
Published: October 2016

The article is devoted to the peculiarities of the organization of spectral EEG patterns in medical school students studying the foreign language. It is shown that students successfully mastering the training program have a higher absolute spectral power of the alpha, beta, and theta rhythms of the left hemisphere. Students with a low level of knowledge of foreign language speech revealed to have mostly right hemisphere dominance. Functional tests with listening texts in a foreign language, as familiar and not previously studied, revealed the specialization of hemispheres in respect to acoustic prosody of foreign languages.