bluuebunny/crossref_metadata_2025 huggingface dataset:
Prescribing Trends of Antidiabetes Medications in Patients With Type 2 Diabetes and Diabetic Kidney Disease, a Cohort Study
Authors: Harris Samantha T. , Patorno Elisabetta , Zhuo Min , Kim Seoyoung C. , Paik Julie M.
Published: August 2021

Objective: To assess changes in
anti-diabetes medication class prescriptions over time among patients with
Diabetic Kidney Disease (DKD), characteristics of patients prescribed these
medications, and prescribers’ specialty.

Methods: A cohort study design using insurance claims
data between 2013 and the first quarter (Q1) of 2020. Included are adult
patients with DKD who initiated a new anti-diabetes medication between 2013 and
2020Q1 (N=160,489 patients). The primary outcome is the yearly and quarterly
percent of medication initiation for each anti-diabetes medication class over
all anti-diabetes medication initiations.

Research Design and Results: For patients
with DKD, sodium-glucose co-transporter-2 inhibitors (SGLT2i) and glucagon-like
peptide 1-receptor agonists (GLP-1RA) initiations steadily increased between
2013 and 2020Q1. Internists and endocrinologists were the most frequent
prescriber specialties. Patients less than 65 years of age had a larger
percentage of all initiations that were SGLT2i or GLP-1RA, 16% and 23%
respectively in 2019, and patients older than 75 years had a smaller percentage
of all initiations that were SGLT2i or GLP-1RA, 11% and 13% respectively in
2019.

Conclusions: For patients with DKD, SGLT2i and
GLP-1RA prescriptions have increased over time, likely reflecting evolving
prescribing patterns in response to the results of recent clinical trials and
new clinical guidelines.
Island medicine: using data linkage to establish the kidney health of the population of Tasmania, Australia.
Authors: Jose Matthew , Raj Rajesh , Jose Kim , Kitsos Alex , Saunder Tim , McKercher Charlotte , Radford Jan
Published: August 2021

ObjectiveTo report (using linked laboratory data) the incidence, prevalence and geographic variation of chronic kidney disease (CKD) across the whole island population of Tasmania, Australia.
MethodsA retrospective cohort study (the Tasmanian Chronic Kidney Disease study (CKD.TASlink)) using linked data from five health and two pathology datasets from the island state of Tasmania, Australia between 1/1/2004 and 31/12/2017. We used data on 460,737 Tasmanian adults (aged 18 years and older, representing 86.8% of the state's population) who had a serum creatinine measured during the study period. We defined CKD as per Kidney Disease Outcomes Quality Initiative, requiring two measures of estimated glomerular filtration rate (eGFR) <60 mL/min/1.73m2, at least three months apart. Kidney replacement therapy (KRT) included dialysis or kidney transplantation.
ResultsWe identified 56,438 Tasmanians with CKD during the study period, equating to an age-standardised annual incidence of 1.0% and a prevalence of 6.5%. These figures were higher in women, older Tasmanians and people living in the North-West region of Tasmania. Testing for urinary albumin:creatinine ratio is increasing, with 28.5% of women and 30.8% of men with stage 3 CKD having both an eGFR and uACR in 2017. Use of KRT was consistently seen in >65% of Tasmanians with eGFR <15mL/min/1.73m2.
ConclusionThere is geographic and gender variation in the incidence and prevalence of CKD, but it is reassuring to see that the majority of people with end-stage kidney failure are actually receiving treatment with dialysis or transplantation.
Análise do julgamento do habeas corpus Nº 358.080 sob a ótica do direito fraternal como categoria jurídica constitucional
Authors: Dias Paulo Cezar , Castilho Lucas de Holanda Martins de
Published: August 2021

Resenha referente ao Acódão nº 358.080FONSECA, Reynaldo Soares. Habeas Corpus nº 358.080 - DF (2016/0144533-6)Disponível em: . Acesso em 20 de outubro de 2020.
O hiperciclo do direito: os desafios do ciberespaço, o jogo e as regras
Authors: Araújo Marilene
Published: August 2021

A presente tese propõe realizar uma leitura do Direito a partir do Jogo, do Hiperciclo e dos fluxos comunicacionais. As mudanças do Direito passam de forma decisiva pelas transformações ocorridas pelas novas tecnologias de informação. O cenário utilizado é o Ciberespaço, onde entoa um mundo de muitas vozes, fluxos de dados e informacionais. As relações humanas passaram a ser pilotadas por este novo mundo virtual, movido pelos fluxos de comunicação e informação, o homem se move digitando ludicamente conforme a arquitetura da rede. Duas apreensões são realizadas entre o Jogo e o Direito. Uma primeira pelo método analógico e a segunda a partir da ideia de dialética, que conduz uma forma de compreensão da complexidade. O jogo – um espaço entre dois – surge como um paradigma explicativo e interpretativo. Jogo e Direito são sistemas evolutivos de interações de regras mutáveis, onde reinam os paradoxos. Os processos comunicacionais animam o jogo de regras móveis no Direito. A comunicação se constitui em um paradigma do Direito, sendo o Ciberespaço um espaço de fluxos de comunicação interativa. Neste ambiente comum a todos, as liberdades são reguladas de forma fragmentada. Ao regular o Ciberespaço, o Direito regula as comunicações existentes, enfrentando problemáticas que sempre emergem quando se regulam liberdades. As problemáticas de regulação passam pela privacidade, desinformação, big data, dentre outras. Ao regular as comunicações existentes, o Direito regula o seu próprio discurso. A comunicação como elemento primeiro que constitui a sociedade é um acontecimento que requer entendimento, em um jogo onde se pode aceitar ou rejeitar (dupla contingência). O Direito mantém as comunicações jurídicas criando e se recriando pelo hiperciclo. Os resultados, tal como no jogo, podem ser o esperado ou o impensável. Um direito vivo e dinâmico aparece em um entrelaçamento recíproco. Ao mesmo tempo, o Direito em um mundo multicêntrico surge fragmentado em um lugar hiperconectado, ocorrendo uma intertextualidade entre ordenamentos jurídicos. As ordens jurídicas se observam e promovem um intercâmbio de aprendizagem. Um Direito fragmentado e um Ciberespaço onde a comunidade mundial está conectada com uma diversidade de regulamentação faz um apelo ao comum.
O NOVO PAPEL DAS EMPRESAS NA PROTEÇÃO DO MEIO AMBIENTE
Authors: Freitas Vladimir Passos
Published: August 2021

O presente artigo tem por objetivo a análise e relevância do compromisso das empresas com a questão ambiental. Na busca deste escopo, foi utilizado o método hipotético-dedutivo, com análise da doutrina, legislação e notícias dos órgãos de comunicação. A pesquisa tem início com a evolução do tema meio ambiente e a desconexão das empresas com a matéria no passado. Na sequência examinam-se as iniciativas tomadas pela Organização das Nações Unidas – ONU para impulsionar o debate, para tanto buscando conectar todos os atores envolvidos. Como resultado da atuação internacional e do agravamento da situação do meio ambiente no mundo, paulatinamente, as corporações foram envolvidas não apenas nos debates ambientais, como também na erradicação da pobreza. A complementar a mudanças na área, os incêndios na Amazônia e os reflexos econômicos negativos que disto decorrem para o Brasil, levaram entes privados a propor mudanças e a pressionar o poder público. Nesta nova realidade, surgem cobranças e propostas junto às empresas, a fim de que assumam um novo protagonismo em relação ao meio ambiente.
Adolescent Contraceptives
Authors: Ara Nasreen Shaikh Zinnat , Huq Sabereen , Huq Saleheen , Shahreen Safinaz
Published: August 2021

Adolescents contraceptive need to be the top most priority in the national policy to prevent the adolescent pregnancies and it’s adverse consequences. All the countries of the world should have their own national strategy liaison with global consensus regarding the Adolescent contraceptives.
Global challenge is to tackle the adolescents Pregnancy. Contraceptives use is the answer. So adolescents should be the centrals to everything we want to achieve, and to the overall success of the 2030 SDG Agenda. Without Contraceptive “SDG achievement” is not possible.
About 21 million 15-19 year old girls in developing countries become pregnant every year. Half of these pregnancies (49%) are unintended.
If we are successful to implement contraceptives among the youngsters, adolescent’s pregnancy complications can be eliminated. But again this needs strong political motivation and hard work of health care providers.
Health care team should design and deliver a Confidential, personalized, adolescent’s friendly service taking into account adolescent's psychosocial & sexual needs.
Almost all methods of contraceptives are suitable for adolescents except few. After taking a comprehensive medical history & assessing risk factors counselling should be done for risks & benefits. Good & sensible communication with women, their husband or partner is important.
It remains a critical aspect in empowering adolescents to make informed choices and only then adolescents will use contraceptives wholeheartedly.
The use of economic engineering in the context of strategic enterprise management
Authors: Kutsyk Petro , Kovtun Oleh , Klochan Viacheslav , Klochan Iryna , Krakhmalova Nina , Prokopenko Oleksii
Published: August 2021

In the article the authors’ interpretation of the "economic engineering" construct in the context of the theory and practice of enterprise strategic management effective system organizing in modern conditions is formulated and substantiated. The idea of using “economic engineering” as a logistics (logistic tool) for constructing an enterprise strategy by generating and presenting possible alternatives for key business aspects of its functioning and development and selecting among them the best options based on their risk assessment is proposed. In order to present and realize the logistics capabilities of a multidimensional morphological matrix in the framework of “economic engineering”, it is proposed to use a framework model of justification and choice of optimal solutions based on their risk assessment, which underpins the idea of frame representation and organization of logistic interconnections.
Respons fisiologis dan agronomis bibit kopi pada kerapatan naungan yang berbeda
Authors: Soleh Mochamad Arief , Sirait Tommy Ario , Ariyanti Mira , Rosniawaty Santi
Published: August 2021

AbstrakTanaman kopi seringkali dibudidayakan di areal hutan, dimana terdapat tanaman tahunan seperti pepohonan yang terus tumbuh sehingga menurunkan intensitas cahaya yang jatuh ke tanaman kopi. Hal ini menjadi masalah bagi pertumbuhan dan perkembangan tanaman kopi yang dinaungi pohon tersebut. Penelitian ini bertujuan untuk menguji fisiologis dan agronomis dua kultivar kopi dalam intensitas naungan yang berbeda untuk mendapatkan informasi kultivar kopi yang terbaik. Percobaan dilaksanakan dari bulan Maret hingga Juni 2020 di Kebun Percobaan Ciparanje, Fakultas Pertanian, Universitas Padjadjaran, Jatinangor, Sumedang, Jawa Barat. Percobaan menggunakan Rancangan Petak Terbagi (Split plot) dengan dua faktor dan diulang sebanyak tiga kali. Taraf dari main plot adalah tanpa naungan, naungan paranet 50%, 60%, 70%, dan 80%, sedangkan taraf dari sub plot adalah kultivar Lini S 795 dan Sigararutang. Hasil penelitian menunjukkan tidak terdapat pengaruh interaksi antara naungan dan kultivar. Penggunaan naungan 70% memberikan pengaruh terbaik terhadap tinggi bibit kopi dan suhu daun, serta kultivar Lini S 975 memberikan pengaruh terbaik terhadap tinggi bibit kopi, luas daun, indeks klorofil, klorofil fluoresens dan suhu daun.Kata Kunci: Kopi, Lini S 795, Klorofil fluorescence, Sigararutang AbstractCultivation of coffee tree in forest areas, where the wooden trees grew previously, it will be causing in decreasing of light intensity that is falling into the ground as long as trees canopy development leading to shade of coffee trees, this is affecting coffee tree growth and development. The objective of this study was to evaluate physiologically and agronomically of two coffee seedling cultivars under net shading densities. The experiment was conducted at Ciparanje Experimental Station, Faculty of Agriculture, Padjadjaran University, Jatinangor, Sumedang, West Java, from March to June 2020. Experimental design used in this research was split plot with two factors and three replications. The main plot was the shading densities which consisted of five levels, namely without shade 0%, net shade 50%, 60%, 70%, and 80%. The subplot was the coffee cultivars, consisted of two levels, namely Lini S 795 cultivar and Sigararutang. All parameters was not indicated any interaction. The results showed that the  70% shade gave the best effect on plant height and leaf temperature. Lini S 795 cultivar gave the best effect on plant height, leaf area, chlorophyll index, chlorophyll fluorescence, and leaf temperature.Keywords: Coffee, Chlorophyll fluorescence, Lini S 795, Net shading, Sigararutang
Japanese Bronze Bells in Switzerland
Authors: Thomsen Hans Bjarne
Published: August 2021

Western museums hold numerous Japanese objects, typically gathered by collectors during travels in Japan and then donated to local institutions. This simple scenario is by no means always the case, as can be seen with the numerous Japanese bronze bells in Swiss museum collections. The story of how the bells changed from holding significant functions within Japanese monastic and secular communities to being sold for their materiality and sheer weight as they travel across the globe tells a complex story of how objects change in meaning as they travel. As the bells were eventually relegated to museum archives, their stories help to shed light on global transfers, interculturality, and cultural misunderstandings, as they narrowly escape destruction. Their stories show the futility of claiming global understanding of art when, despite globalization, we are in the end products of our own localized traditions and understandings.
PENGEMBANGAN STANDAR DESAIN LAYANAN CLOUD BERDASARKAN ISO/IEC 20000: STUDI KASUS PT. XYZ
Authors: Adriansyah Ahmad Fikri , Hardian Bob , Guarddin Gladhi
Published: August 2021

PT XYZ is now transforming its business from traditional telecommunication provider to an ICT (Information & Communication Technology) provider in order to deal with current stringent business competition. One of its strategic initiatives is to improve Cloud service market penetration based on the fact from market size analysis result which has reported that Cloud service would appear as an IT service with highest growth throughout Asia Pacific region from 2013 to 2018 (i.e., 49%). However, PT XYZ has reported its Cloud service sales only achieved 52% of its total revenue target in 2014 fiscal year. One of the root causes found is the lack of standard in performing design on Cloud service. As ISO/IEC 20000 certification holder, PT XYZ has to improve its IT service management practices continuously including its service design stage. This research goal is to build design standard on Cloud service in PT XYZ using two internationally recognized Information Technology Service Management (ITSM) frameworks, i.e. Information Technology Infrastructure Library (ITIL) version 3 and Microsoft Operation Framework (MOF) version 4, as well as Cloud Computing Reference Architecture (CCRA) and guidance on the application of ISO/IEC 20000-1 to Cloud Services (ISO/IEC TR 20000-9:2015). As the result, a design process flow and design documentation templates are proposed to be used as Cloud service design standard in PT XYZ.
PELAKSANAAN PROGRAM MAGANG TALENTA SERVICE MELALUI KEGIATAN BANK MINI DI PT. BANK MAYBANK INDONESIA, Tbk
Authors: Sigarlaki Benny Ismail , Gunadi Andi Ahmad , Winata Widia
Published: August 2021

Talenta service program is a education program and training for fresh graduate from any university to get some knowledge in the world of banking. This program using the development comprehenship principle with combine learning in the class learning in the complete and modern mini bank facility and learning in the field through on the job training (OJT) activities. The purpose of this study is to measure the succes of student talent services at PT. Bank Maybank Indonesia, Tbk. This research method uses descriptive qualitative research method that is trying to describe implementation of education and training program at PT. Bank Maybank, Tbk with a sample of 10 (ten) student service talent/interships. The result of this study show that by using mini bank simulations/practicum on education and training programs, talent service program have made it easier for students to understand lessons and can increase students enthusiasm and interest in following the learning process.
PENGEMBANGAN MODEL CASE CONFERENCE PADA ANAK BERKEBUTUHAN KHUSUS
Authors: Rosyidin Dindin , Zulfitria Zulfitria , Wicaksono Dirgantara
Published: August 2021

Each of children with special need in Labschool FIP UMJ is assisted by classroom teacher, assistant teacher, shadow teacher, and some therapists in his house. They have their own program and achievement so that it can cause overlapping among them.  Thus it is necessary to develop and integrate a holistic model and integrated program to handle children with special needs.  The study provides the development of Case Conference Model at children with special need. The study used research and development (R&D). The model used in the study is ADDIE model. It stands for  analysis, design, develop, implement, and evaluate. The population in the study is special need’s children at Labschool FIP UMJ. The output of the study is case conference model which can be used for children with special need.  The implementation of Case Conference model can help teacher, shadow teacher, parents and principle in dealing with special need’s children.
RANCANGAN PEMBELAJARAN JARINGAN KOMPUTER MODEL DICK DAN CAREY BERBASIS MANAJEMEN LAYANAN INFORMATION TECHNOLOGY INFRASTRUCTURE LIBRARY (ITIL)
Authors: Sallu Sulfikar - , Qammaddin Qammaddin
Published: August 2021

Computer Network Learning is one of the teaching and learning processes in the compulsory Computer Networking course in a study program in the computer science family. Dick and Carey designs are the general components of a learning material from the procedures that will be used in learning to produce the desired learning outcomes. Furthermore, Information Technology Infrastructure Library (ITIL) is one of the frameworks that is part of Service Management in IT governance to make it easier to evaluate IT services and to find out things that must be developed in that service. The purpose of this study was to produce a design concept in the ITIL-based dick and carey model of computer network learning design. The method used is a literature review that utilizes all available reference sources. The result achieved is the ITIL-based Dick and Carey model computer network course concept which will create a quality computer network learning design.
PEMBELAJARAN KEMUHAMMADIYAHAN : EVALUASI PROGRAM DI UNIVERSITAS MUHAMMADIYAH PROF. DR. HAMKA (UHAMKA)
Authors: Duani Almisar Hamid
Published: August 2021

Tujuan penelitian evaluatif ini adalah untuk menilai penyelenggaraan program pembelajaran Kemuhammadiyahan yang menjadi mata kuliah wajib di seluruh Perguruan Tinggi Muhammadiyah dan Aisyiah (PTMA). Penelitian dilakukan di Universitas Muhammadiyah Prof. Dr. Hamka (Uhamka) pada bulan Januari sampai dengan April 2020. Penelitian ini adalah penelitian kualitatif. Informan dipilih dengan teknik purposive, terdiri dari unsur mahasiswa, dosen, pimpinan Uhamka, dan Pimpinan Majelis Diktilitbang PP Muhammadiyah. Data dikumpulkan dengan teknik wawancara, Focused Group Discussion (FGD), dan dokumentasi. Data dianalisis dengan evaluasi model CIPP Stufflebeam.Hasil penelitian menunjukkan masih ditemukan sejumlah kendala dalam pembelajaran Kemuhammadiyahan, antara lain dari sisi konteks, masih terjadi perdebatan mengenai muatan isi kurikulum. Upaya pembaharuan sudah dilakukan dengan diterbitkaannya buku ajar baru.Dari sisi input ditemui kendala menyangkut ketersediaan, kualifikasi, dan sertifikasi dosen Kemuhammadiyahan. Dari sisi proses, durasi waktu pembelajaran yang hanya 2 sks dirasakan tak cukup untuk menerapkan pembelajaran dengan strategi pemberdayaan. Terakhir,dari sisi produk, kendati terjadi perkembanganpandangan mahasiswa tentang Muhammadiyah, namun perkembangan tersebut belum mengubah secara signifikan tradisi keagamaan yang mereka yakini selama ini.
PENGEMBANGAN DESAIN PEMBELAJARAN SISTEM BASIS DATA
Authors: Ruliah Ruliah , Bahar Bahar , Pratiwi Andita Suci
Published: August 2021

Instructional design plays an important role in improving the quality of learning and the learning experience of students. But in fact, many universities (especially in the field of Information Technology) have not developed a structured learning design, so that the learning process becomes ineffective. This paper presents a database system learning design model using the Borg and Gall step 1 development model and adapting all stages in the Dick and Carey model. The research consists of four main stages: conducting a preliminary study to find information about the learning product to be developed; develop products based on research findings; conduct field trials on the products developed; and revise products based on test results. The product quality of the developed learning design model is measured from aspects of validity and aspects of practicality. Validity is assessed through expert validation (database system learning material expert, instructional design expert, graphic media expert, and linguist). The measurement results obtained an average value of 5 (on a scale of 1-5), which means that the product of the learning design model developed is included in the valid category. Practicality is measured based on the responses of students and teachers. The results of the practicality measurement obtained an average value of 4.56 (on a scale of 1-5), which means that the product of the learning design model developed is included in the Practically used category
Основы статистического и исследовательского анализа данных на Python
Authors: Ковальчук А.О. , Капитан В.Ю.
Published: August 2021

Материал пособия делится на 4 главы. В первой главе описывается роль анализа данных в современном мире. Во второй главе дается материал, посвященный практическому применению математической статистики и теории вероятностей при анализе данных на Python. В третьей главе приводится описание методов сбора и предобработки данных. В четвертой главе рассматриваются основные методы визуализации данных. Практические материалы и задания для студентов выполнены с использованием Google Colaboratory. Пособие знакомит студентов с базовыми понятиями и методами анализа данных, примерами их использования в задачах обработки, прогнозной аналитики и информационного поиска. Предназначено для студентов, обучающихся по программе высшего образования естественнонаучных и физико-технических направлений подготовки.
Clínica da Atividade Docente e intervenções a partir da autoconfrontação e da instrução ao sósia
Authors: Muniz-Oliveira Siderlene , Lima Anselmo , Althaus Dalvane
Published: August 2021

O objetivo deste artigo é apresentar uma proposta de implementação de uma Clínica da Atividade Docente, seguida de uma explanação de dois métodos que podem ser utilizados nesse processo, a autoconfrontação e a instrução ao sósia. Para exemplificar a sua utilização, serão apresentados dois tipos de ação de intervenção com esses métodos. O primeiro foi realizado com professores universitários de diferentes áreas com o método autoconfrontação; o segundo, com professores do ensino fundamental e médio da rede estadual de ensino com o método instrução ao sósia, tendo como observadores alunos de licenciatura, futuros professores. Os resultados mostram a importância desses métodos, tanto para formação inicial quanto para formação continuada, tendo os professores como protagonistas de seu trabalho.
Replacing the Content in e-Abacus Diagram II
Authors: Mahmood Ammar Seddiq , Basher Fatmah Ahmed
Published: August 2021

In our normal life, we sometimes need a process of replacing something with another to get out of the stereotype. From this point of view, Mahmood’s attempted in the year 2020 to replace the content in the first main e-abacus diagram. He found the general rule for finding the value of the new partition after the replacement from the original partition. Here we raise the question: Can we find the appropriate mechanisms for the remainder of the main e-abacus diagram?
Some Properties of Fuzzy Inner Product Space
Authors: Kider Jehad R.
Published: August 2021

Our goal in the present paper is to introduce a new type of fuzzy inner product space. After that, to illustrate this notion, some examples are introduced. Then we prove that that every fuzzy inner product space is a fuzzy normed space. We also prove that the cross product of two fuzzy inner spaces is again a fuzzy inner product space. Next, we prove that the fuzzy inner product is a non decreasing function. Finally, if U is a fuzzy complete fuzzy inner product space and D is a fuzzy closed subspace of U, then we prove that U can be written as a direct sum of D and the fuzzy orthogonal complement    of D.
اثر المخاطر غير النظامية في درجة الامان المصرفي دراسة تطبيقية في عينة من المصارف التجارية المسجلة في سوق العراق للاوراق المالية للفترة من (2007-2019)
Authors: Mohamed AL-hakim Nasreen
Published: August 2021

هدف البحث إلى التعرف على تأثير المخاطر غير النظامية في درجة الامان المصرفي ، واستند البحث إلى فرضية رئيسة مفادها: تؤثر المخاطر غير النظامية تأثيراً معنويا وعكسياً في درجة الامان المصرفي .، وتم استخدام عدد من النسب المالية لتحليل البيانات التاريخية للمصارف (عينة البحث) والمكونة من (7) مصارف للمدة من (2007-2019) ، وتم استخدام انموذج Panel Data  للتعرف على علاقة التاثير بين متغيرات البحث وفق برامج EVIES10 ، وقد تم التوصل من خلال البحث إلى جملة من الاستنتاجات ، من أهما : وجود علاقة عكسية معنوية بين المخاطر غير النظامية ودرجة الامان المصرفي ، كما قدم البحث مجموعة من المقترحات ، من اهمها : ضرورة العمل على إيجاد نوع من التوزان بين الامان المصرفي وكل من مخاطر الائتمان ، ومخاطر السيولة ، ومخاطر رأس المال ، مخاطر العائد .ويتطلب ذلك العمل على الالتزام بالانظمة والقوانين التي يحددها البنك المركزي وخاصة فيما يتعلق بالنسب المالية ذات الصلة بالسيولة القانونية والسيولة التجارية ، ونسبة الائتمان المصرفي ، ونسبة حقوق الملكية مقسومة على اجمالي الموجودات.
تایبه‌تمه‌ندی مۆرفیمه‌ ڕێزمانیه‌كانى ده‌ڤۆكى كۆیه‌، له‌ ده‌ڤه‌رى كۆیه‌, لێكۆلینه‌وه‌یێكى به‌راووردكارییه‌
Authors: Taher Dhaher Kawa , B. Rashid Muayad
Published: August 2021

مۆرفۆلۆجى ئاستێكه‌ له‌ ئاسته‌كانى زمان و به‌شێكى سه‌ره‌كییه‌ له‌ ڕێزمان و گرنگییێكى تایبه‌تى له‌ بوارى ئه‌و گۆڕانكارییانه‌ى به‌ سه‌ر هه‌ر زمانێكدا دیت، له‌ جیهاندا هه‌یه‌. چونكه‌ سه‌ره‌تاى هه‌ر گۆڕانكارییێكى به‌ سه‌ر زماندا دێت ئه‌و گۆڕانكارییه‌ له‌ مۆرفیم ده‌ست پێده‌كات. له‌م لێكۆلینه‌وه‌یه‌دا به‌ ناونیشانى تایبه‌تمه‌ندی مۆرفیمه‌ ڕێزمانیه‌كانى ده‌ڤۆكى كۆیه‌، له‌ ده‌ڤه‌رى كۆیه‌, لێكۆلینه‌وه‌یێكى به‌راووردكارییه‌، جه‌خت له‌لایه‌نێكى مۆرفیم ده‌كات كه‌ مۆرفیمى ڕێزمانى یه‌ له‌ نێوان سێ ده‌ڤۆكى (هه‌ولێر، كۆیه‌، سلێمانی)دایه‌، بۆ دیاركرنى لایه‌نی وه‌كیه‌ك و لایه‌نی جیاواز له‌ نێوان هه‌رسێ ده‌ڤۆكدا و دیاركرنى ڕێژه‌ی هه‌رده‌ڤۆكێك له‌ ده‌ڤه‌رى كۆیه‌، بۆ ئه‌م مه‌به‌سته‌ش زارده‌مى خه‌لكى وه‌رگیراوه‌ وه‌كو كه‌ره‌سته‌ى خاوى لێكۆلینه‌وه‌ و شیكردنه‌وه‌ى ئه‌و كه‌ره‌ستانه‌ به‌پیێ ڕێبازى به‌راووردی.
Evaluating the effect of a water exercise routine on the postural stability of the elderly
Authors: Olaya Mira Natalia , Soto Cardona Isabel Cristina , Martínez Osorno Laura Vanesa , Mercado Díaz Darwin Raúl , Henao Ceballos Luisa María
Published: August 2021

Background:
Postural stability enables humans to maintain the center of mass of their body within their base of support. Nevertheless, over time, such stability is affected by different factors such as age, repetitive strain, and accidents. Although studies in this field have investigated the effectiveness of hydrotherapy, only a few of them have explored its influence on postural stability, which is reflected in a lack of research that estimates its impact on rehabilitation.

Aim:
To determine the immediate and final effects of an aquatic routine protocol on the postural stability of elderly subjects.

Methods:
The postural stability of 20 adults over 60 years of age was analyzed using electromyographic and baropodometric methods. Electromyographic signals were obtained from the tibialis anterior, soleus, both gastrocnemius, vastus medialis, and biceps femoris to calculate the coactivation percentage of the muscles in charge of postural stability. The baropodometric data were collected to analyze the area of the stabilometric ellipse, mean plantar pressure, and weight distribution percentage.

Results:
The outcome of both methods revealed improvements in the elderly patients after the aquatic routine protocol was applied, which indicates that the type of water exercises implemented in this study has positive effects on their postural stability.

Conclusion:
The postural stability of the elderly participants was improved after each session because their stability index decreased along with the electrical activity of some muscle pairs, their body weight was better distributed, and the area of body oscillation was reduced. However, this effect was immediate and not final.
Maternal and cord blood parameters are associated with placental and newborn outcomes in indigenous mothers: A case study in the MINDI cohort
Authors: González-Fernández Doris , An Yining , Plourde Hugues , Pons Emérita del Carmen , Sinisterra Odalis Teresa , Rueda Delfina , Murillo Enrique , Scott Marilyn E , Koski Kristine G
Published: August 2021

Background:
Multiple infections, nutrient deficiencies and inflammation (MINDI) occur in indigenous communities, but their associations with perinatal outcomes have not been described.

Objective:
To assess maternal and cord blood micronutrient and inflammation status in peripartum mothers from the Ngäbe-Buglé comarca in Panama, and their associations with placental and infant outcomes.

Methods:
In 34 mother-newborn dyads, placental weight and diameter were measured, and maternal and cord blood were processed for complete cell counts, serum C-reactive protein, ferritin, serum transferrin receptor (sTfR), vitamins A and D. Blood volumes were calculated using Nadler’s formula.

Results:
Mothers had low plasma volume (<2.8 L, 96%), vitamin A (52.9%), vitamin D (29.4%), iron (58.8%) and hemoglobin (23.5%), but high hematocrit (>40%, 17.6%) and inflammation (C-reactive protein >8.1 mg/L, 85.3%). Birthweights were normal, but the low placental weight (35.3%), low head circumference Z-scores (17.6%), and low cord hemoglobin (5.9%), iron (79.4%), vitamin A (14.7%) and vitamin D (82.3%) were identified. Maternal and cord vitamin D were highly correlated. Higher maternal plasma volume was associated with heavier placentae (β= 0.57), and higher cord D (β= 0.43) and eosinophils (β= 0.43) with larger placentae. Hemoconcentration (higher cord hematocrit) was associated with lower newborn weight (β= -0.48) and head circumference (β= -0.56). Inflammation [higher maternal neutrophils (β= -0.50), and cord platelets (β= -0.32)] was associated with the lower newborn length and head circumference.

Conclusion:
Maternal-newborn hemoconcentration, subclinical inflammation and multiple nutrient deficiencies, particularly neonatal vitamin D deficiency, were identified as potential targets for interventions to improve pregnancy outcomes in vulnerable communities.
Bolesław Wieniawa Długoszowski – lekarz, generał, wolnomularz
Authors: Gniadek Waldemar
Published: August 2021

This article discusses the life and activities of a Polish Army general, a doctor, diplomat and freemason, such as Boleslaw Wieniawa Dlugoszowski. After Poland regained independence, he became the personal adjutant of Marshal Jozef Pilsudski. After the outbreak of World War II, President Ignacy Moscicki appointed him as his successor, in case the office was vacated before peace was made. He is one of the most colourful figures in interwar Poland. He was known for his predilection for beautiful women, fast horses and loud fun. On the one hand, such a view of life caused unusual affection among some and undisguised aversion among others, especially among opponents of his political camp. He was also a writer, wrote poems, painted and maintained constant contact with the artistic community. For several years he was Poland’s ambassador to Rome, he was friends with many outstanding people not only in Poland, but also in the whole of Europe. After settling in the United States, he lived in New York. He was also a journalist and editor-in-chief of “Dziennik Polski” in Detroit. He died tragically in 1942, a few days before taking over the diplomatic post in Havana. He was remembered by his posterity as the author of many popular sayings, later widely quoted throughout the country.
Medyczne i humanistyczne zagadnienia związane z psychodermatologią w praktyce lekarza rodzinnego, ginekologa i seksuologa
Authors: Jarząbek-Bielecka Grażyna , Plagens-Rotman Katarzyna , Mizgier Małgorzata , Merks Piotr , Czarnecka-Operacz Magdalena , Kędzia Witold , Bielecki Marek
Published: August 2021

A family doctor, as well as a sexologist, gynecologist, in his medical practice encounters problems related to skin diseases significantly affecting the sense of femininity or masculinity. An example of such an issue, especially in gynecology of developmental age, is the problem of skin changes associated with androgenization syndromes. Typical dermatological diseases are sometimes associated with enormous pain, not only physical, but also mental, resulting from the fact that skin disease processes significantly disfigure the body, lower self-esteem and significantly affect the sexual sphere. Selected aspects related to the holistic approach to the issue of pain and suffering, also related to skin lesions, are presented. This issue, like all medical fields, is a source of philosophical reflection. It is inseparable from psychodermatology. The experience of the SARS-CoV-2 coronavirus pandemic, taking into account skin lesions, also prompts a similar search.
Fr. Karl Urban (1864–1923) – Researcher of the History of Upper Silesia
Authors: Górecki Piotr
Published: August 2021

The aim of the article is to present the person and scientific achievements of Fr. Karl Urban (1864–1923), in the years 1899–1923 a priest at Sadów in the Lubliniec deanery. He himself – being the son of Carl Urban (1836–1922), a teacher in Upper Silesian schools, the author of a few books combining the subjects of pedagogy and history – he was engaged in scientific activity almost all his life. He published some of his research works in the Silesian scientific journal: „Oberschlesische Heimat. Zeitschrift des OberschlesischenGeschichtsvereins”, and he was actively participating in the activities of the Upper Silesian Historical Society founded in 1904. The members of that society focused their work mainly on the history of local communities, creating accounts contributing to the synthetic history of Upper Silesia. The preliminary archival query found the first articles of Fr. Urban, concerning the history of the lands of Lubliniec and Koszęcin. The author shares the preliminary results of his research, the aim of which is to publish a book about this forgotten researcher of local history on the hundredth anniversary of his death.
Christian Tradition and (Post) Modernity in the Context of Cardinal Stefan Wyszyński’s Personalist Concept of Culture (1)
Authors: Ficek Ryszard
Published: August 2021

In the context of Cardinal Wyszyński’s personalistic concept, a man understood as a spiritual, as well as corporal being, created by God in His image and likeness, endowed with human dignity from the moment of conception, the subject of rights and duties appears as the focus of the Christian perception of culture. The analysis of contemporary cultural reality, then, carried out in the above article in the light of the Christian tradition allows us to express the discussed issues in terms of a vocation addressed to every human being. Its position to the realities of earthly life emphasizes that in the creative activity of culture, one should see the most appropriate way of realizing the fullness of the human personality not only in the temporal dimension but also in the supernatural one. Moreover, emphasizing such elements as the human person, family, Nation, state, the international community, culture, economy, and politics understood in an integral way, as well as the Church proclaiming the universal message of salvation, the Primate’s vision of culture exposes a praxeological character, rooted in particular human existence. It allows not only the direct inclusion of the human person in the current of civilization and cultural changes but also consents the human being to discover the right place in the dynamically changing contexts of the contemporary world.
„Dziecko Waszej troski”
Authors: Olszar Henryk Alojzy
Published: August 2021

Celem artykułu jest prześledzenie choroby Heleny Hoffmann i ustalenie personaliów lekarzy, którzy przychodzili jej z pomocą w latach 1928–1936. Obok nich uczynki miłosierdzia wobec niej wykonywały Siostry Maryi Niepokalanej, zwłaszcza gdy asystowały jej w badaniach i wspierały w chorobie. Narracja, podana w formie syntezy, oparta jest na analizie dostępnych źródeł archiwalnych i opracowań. Autor ustalił, że zdrową „Oblubienicą Krzyża” zajmował się psychiatra i neurolog Waldemar Kunick. Jej stany chorobowe badali: laryngolog Georg Krischke, ordynator Karl Stefan Klein, lekarz domowy Artur Pusch, neuropatolog, rentgenolog i elektrodiagnostyk prof. Ludwig Mann, lekarz domowy Gustav Skrobek, lekarka Else Kalinke, radiolog i onkolog prof. Paul Lazarus, specjalista od leczenia gruźlicy i zastosowania diety w chirurgii prof. Adolf Herrmannsdorfer, okulista Adalbert Richter, laryngolog Mieczysław Karol Stawiński i okulista Stanisław Mirecki. W sumie autor ustalił nazwiska i specjalizacje dwunastu lekarzy.
Modlitwa Jezusa w Getsemani w wersji synoptycznej (Mt 26,36-46; Mk 14,32-42; Łk 22,39-46) jako paradygmat oddania się woli Ojca
Authors: Witkowski MS Stanisław
Published: August 2021

Artykuł ukazuje zmaganie się Jezusa w Getsemani, aby mogła ostatecznie zrealizować się wola Boża. Szczególnie akcentują ten motyw Marek oraz Mateusz. W wersji Łukasza Jezus jako wzorcowy Nauczyciel jest gotowy od razu pełnić zamysł Ojca. Ukazana przez trzeciego Ewangelistę walka (avgwni,a) wyraża napięcie Jezusa, Jego emocje, aby stało się to, co przygotował dla Niego Bóg. Temat związany z modlitwą w Getsemaniznajduje swój wyraz także w Hbr 5,7-8, w kontekście kapłaństwa Jezusa, które od samego początku ściśle łączyło się z Jego ofiarą z życia. Przytoczony fragment z Listu do Hebrajczyków wykazuje różnice w interpretacji. W świetle synoptyków wydaje się jednak, że eu vla,beia – „bojaźń” powinna przyjąć odcień respektu, czci wobec woli Ojca. Jej rozpoznaniu towarzyszyło cierpienie Jezusa, które zaowocowało Jego pełnym posłuszeństwem. Wola Boża jako ostateczne kryterium decyzji znajduje swoje potwierdzenie także w pierwotnym Kościele. Wspólnota z Cezarei Nadmorskiej wyraża pragnienie jej realizacji, gdy wszystkie zabiegi zostały wyczerpane, aby powstrzymać Pawła przed zbliżającą się jego śmiercią (Dz 21,11-14). W ten sposób oddanie się woli Ojca, staje się punktem odniesienia we wszystkich okolicznościach chrześcijańskiego życia.
Ignacy Dziadek w piśmiennictwie i rodzinnym przekazie
Authors: Dziadek Krystian Albert
Published: August 2021

Ignacy Dziadek był synem rolnika potrafiącego czytać i pisać, którego wybrano na sołtysa i sędziego ludowego. Ignacy jako samouk posługiwał się językami łacińskim i niemieckim, z którego przetłumaczył i wydał wiele książek religijnych, głównie modlitewników. Kapłanami zostali jego dwaj synowie i wnuk – Albert Willimsky, którego uznano męczennikiem II wojny światowej. Z jego bogatej biblioteki korzystali młodzimieszkańcy Mionowa, a szczególnie Johannes Chrząszcz, późniejszy kapłan i historyk Śląska. Ignacy Dziadek był również posłem do Pruskiego Zgromadzenia Narodowego. W artykule scharakteryzowano jego spuściznę literacką, a także przedstawiono jego osobę w oparciu o zachowane rodzinne przekazy.
Surgical correction of pediatric spinal deformities with coexisting intraspinal pathology: A case report and literature review
Authors: Li Daphne , Anderson Douglas E. , Nockels Russ P.
Published: August 2021

Background:

Surgical correction of spinal deformities with coexisting intraspinal pathology (SDCIP) requires special consideration to minimize risks of further injury to an already abnormal spinal cord. However, there is a paucity of literature on this topic. Here, the authors present a pediatric patient with a residual pilocytic astrocytoma and syringomyelia who underwent surgical correction of progressive postlaminectomy kyphoscoliosis. Techniques employed are compared to those in the literature to compile a set of guidelines for surgical correction of SDCIP.

Methods:

A systematic MEDLINE search was conducted using the following keywords; “pediatric,” “spinal tumor resection,” “deformity correction,” “postlaminectomy,” “scoliosis correction,” “intraspinal pathology,” “tethered cord,” “syringomyelia,” or “diastematomyelia.” Recommendations for surgical technique for pediatric SDCIP correction were reviewed.

Results:

The presented case demonstrates recommendations that primarily compressive forces on the convexity of the coronal curve should be used when performing in situ correction of SDCIP. Undercorrection is favored to minimize risks of traction on the abnormal spinal cord. The literature yielded 13 articles describing various intraoperative techniques. Notably, seven articles described use of compressive forces on the convex side of the deformity as the primary mode of correction, while only five articles provided recommendations on how to safely and effectively surgically correct SDCIP.

Conclusion:

The authors demonstrated with their case analysis and literature review that there are no clear current guidelines regarding the safe and effective techniques for in situ correction and fusion for the management of pediatric SDCIP.
Transfusion Related Acute Lung Injury (TRALI): A Rare Case after Single Packed Red Blood Cell (PRBC) Unit Transfusion
Authors:   Department of Transfusion Medicine, Sparsh Hospital, Yeshwantpur, Bangalore, India, PM Bala Bhasker
Published: August 2021

Transfusion Related Acute Lung Injury (TRALI) is a rare but serious adverse event of allogeneic blood component transfusion, manifested typically by shortness of breath, a non-productive cough, fever, and hypotension, mostly seen after plasma component transfusion collected from female donors. We here present a rare case of TRALI requiring Intensive Care Unit (ICU) support after transfusion of single Packed Red Blood Cell (PRBC) unit collected from a male donor. The present case emphasizes that TRALI to be ruled out first in any patient showing acute /respiratory distress within 6hrs of transfusion, with prompt management and notification to transfusion services.
Traumatic Dislocation of the Knee Unsuitable for the Reconstruction of Ligamentous Injuries Because of Vascular Injury: A Case Report
Authors:   Department of Orthopaedic Surgery, Surgical Science, Tokai University School of Medicine, Kanagawa, Japan, T Ukai , H Kosuke ,   Department of Orthopaedic Surgery, Surgical Science, Tokai University School of Medicine, Kanagawa, Japan, M Watanabe ,   Department of Orthopaedic Surgery, Surgical Science, Tokai University School of Medicine, Kanagawa, Japan
Published: August 2021

Traumatic dislocation of the knee is rare, but often requires surgical intervention because complications frequently occur, including various ligamentous injuries. In this study, we report a case of knee dislocation with ligamentous injuries and injury to the popliteal artery. The patient was a 32-year-old man. He fell while bouldering and was diagnosed with dislocation of the right knee and multiple ligamentous injuries. Upon examination, we found that his right dorsal foot was numb, and the dorsal artery of the right foot was not palpable. His right leg felt cold compared to the other leg. Magnetic resonance imaging revealed injuries to the anterior cruciate ligament, posterior cruciate ligament, and lateral collateral ligament. Computed tomography revealed that the patient’s right popliteal artery was partially obstructed. We planned to reconstruct the injured ligaments. Prior to the surgery, the radiologist performed angiography, and the patient’s popliteal artery became completely obstructed during angiography; therefore, revascularization was performed immediately. Although the blood flow in the right leg recovered, it remained cold, and we did not reconstruct the ligamentous injuries. Knee dislocation requiring revascularization is quite rare. However, it causes severe dysfunction of the knee. Thus, meticulous and frequent evaluation of vascular injuries is necessary for the treatment of knee dislocation.
Tratamento cirúrgico de lesão do ligamento cruzado anterior em paciente com imaturidade esquelética pela técnica de Kocher, com seguimento pós operatório de 6 anos: relato de caso / Surgical treatment of anterior cruciate ligament injury in a patient with skeletal immaturity by the Kocher technique, with a postoperative follow-up of 6 years: case report
Authors: Netto Alfredo dos Santos , Kawano Leticia Sano , De Oliveira Victor Marques , Severino Nilson Roberto , Camargo Osmar Pedro de Arbix de , Cury Ricardo de Paula Leite
Published: August 2021

Introdução: No tratamento cirúrgico da lesão do ligamento cruzado anterior (LCA) em pacientes pediá-tricos, é necessário o equilíbrio entre a restauração da anatomia, e o risco de dano à fise de crescimento durante o ato operatório. Objetivo: Relatar caso de paciente com 9 anos, de-senvolvimento puberal de Tanner I, submetido a reconstrução do LCA pela técnica de Ko-cher, técnica de reconstrução extra fisária com enxerto de trato iliotibial autólogo.Palavras chave: Joelho, Reconstrução do ligamento cruzado anterior, Maturidade sexual
AbstractIntroduction: In the surgical treatment of anterior cruciate ligament (ACL) injury in pediatric patients, a balance between anatomical restoration and the risk of damage to the growth plate during the surgery is necessary. Objective: Report a case of a 9-year-old patient, pubertal development of Tanner I, underwent ACL reconstruction using the technique of Kocher et al., a physeal-sparing reconstruction technique with autologous iliotibial tract graft.Keywords: Knee, Anterior cruciate ligament reconstruction, Sexual maturation
Repercussion of piperine on pharmacokinetics parameters of eletriptan in albino rats: Involvement of CYP3A and P-GP inhibition
Authors: Hematheerthani N  , Siva Reddy CH  , Prameela Rani A  , Suresh Kumar P
Published: August 2021

Eletriptan is at the type of triptan medication suggested for the management of episodes of severe headache with or without aura. Piperine (1-piperoylpiperidine) is a pure alkaloid as well as the basic tanginess material from the pipli and peppercorn. There are signs that piperine inhibits Cytochrome P-450 enzymes and P-glycoprotein, rather than arouses, drug metabolism generally, thus increasing the bioavailability and effect of several medications. The analysis was undertaken to assess the results of Piperine on the pharmacokinetics of Eletriptan. Samples of blood were taken at different time points for example 0 (predose), 0.5, 1.0, 1.5, 2.0, 2.5, 3.0, 3.5, 4.0, 6.0, 8.0, 12, 24 hours post-treatment. The plasma concentration of Eletriptan was estimated with the HPLC procedure.  In our study Cmax, Tmax, AUC0-24 , AUC0-8, AUC%, AUMC0-24, AUMC0-8, t1/2, MRT0-24, MRT0-8 and Volume of distribution were increased by approximately 51.76%, 7.55%, 72.93%, 84.42%, 42.72%, 93.56%, 128.82%, 19.97%, 11.74%, 23.96% and 3% respectively, where as clearance decreased by 42.10% when eletriptan co-administered with piperine. In summary, the results obtained herein imply that Piperine is improving the bioavailability of Eletriptan by strengthening the exposure (AUC) of their Eletriptan when concomitantly administered by the oral route. The Piperine improved the oral bioavailability of eletriptan by inhibiting CYP3A and P-GP in rats. This observation indicates the possibility that the combo of piperine along with other CYP3A and P-GP double substrates can also enhance bioavailability.