bluuebunny/crossref_metadata_2025 huggingface dataset:
RTI: A Powerful Tool for Promoting Transparency in Jammu and Kashmir
Authors: Dar Showkat Ahmad
Published: June 2022

Kashmir, India's highest point is 566 kilometres away from the capital city of New Delhi. Visitors to this region, which is bordered by the Himalayan and Pir Panjal ranges, marvel at the breath-taking scenery. The RTI Act was implemented by the state government as a mechanism for resolving administrative complaints. Knowing that corruption can be a deadly disease, Indian-controlled Jammu and Kashmir state has taken steps to ensure citizens have access to reliable, up-to-date information about their government. This has been used a lot by citizens and the media to find out about corruption, government work, and how much money the state of Jammu and Kashmir spends. This is done to make sure that the state is transparent and has good governance. State law has changed since Article 370 was repealed. The Central RTI Act 2005 now rules in the state after that law was changed. This paper takes a gander at the adequacy of the right to information act in Jammu and Kashmir to check whether there is any defilement nearby. As the paper shows, the RTI Act has been truly adept at lessening contrasts in admittance to data and looking into corruption. The individuals who work for the public authority have become more responsive
Implementing Error Correction Strategies to Enhance Arts & Science College Students’ Writing Skills
Authors: Selvi M.D.Thamarai , Saranya Dr. P.
Published: June 2022

The purpose of the study is to implement error correction strategies to enhance arts & Science college students’ writing skills. Participants of the study were final year students of UG and PG from Dhanalakshmi Srinivasan Arts and Science College for Women, Perambalur. An Online Google form and a survey questionnaire were administered in this study to collect data. Five point likert scale was incorporated in the questionnaire. Respondent’s size is two hundred and seventeen (217) female students. The problem statement of the study is that the female students of Arts and Science College struggle to frame a correct sentence with proper sentence structure. They are unable to frame a sentence with complete meaning. The hypothesis of the study is to enhance the arts and science female students' writing skills through the gallery walk technique and three error correction techniques. The objectives of the study are i) to enhance the writing skills of arts and science college female students, ii) To develop the ability of students to understand the importance of sentence making, iii) To bring awareness about the gallery walk technique, self, peer, and teacher correction, and its benefits. The research questions are i) Will the students develop their writing skills through self-correction, peer-correction, and teacher-correction strategies? ii) Will students enhance sentence structure and sentence pattern through the gallery walk technique? iii) Will students improve their language proficiency through texts and images? The collaborative theory is utilized in this study. The findings of the study are that through gallery walk and self-correction, peer-correction, and teacher-correction strategies, students have shown involvement and improvement.
Amerikaanse perspectieven over onderhandelen en bemiddelen
Authors: Verbeke Alain-Laurent
Published: June 2022

The cradle of problemsolving negotiation and mediation lies in the USA

Hence it is always interesting to look across the ocean to enrich our thinking and practice in ADR with some fresh insights and perspectives from the USA. As an add-on to my book on Constructive conflict and dispute management (Constructief omgaan met conflicten en geschillen. Inleiding in probleemoplossend onderhandelen en bemiddelen, A.-L. Verbeke & G. Vervaeke, Boomjuridisch Antwerpen 2022, 173 p.; also published in TMD 2021 (25) 2, 14-149), I have requested three American good friends and colleagues of eminent standing in the field, to give a brief reflection on video on a topic of each one of the three chapters of the book. You can watch these interesting perspectives via the QR codes in this article.

In the first clip, related to the first chapter on communication, Professor of Practice at Harvard Law School Sheila Heen comments on some aspects of "Difficult Conversations", the best-selling book of which she is a co-author. On the second chapter on negotiation, we focus on the complex question when to negotiate, when to fight when your opposing party feels like a demon. Professor Robert H. Mnookin, author of the best-selling book "Bargaining with the Devil", is our expert guide in the second clip. He is the Williston Professor of Law at Harvard Law School, Director of the Harvard Negotiation Research Project and Emeritus Chair of PON, the famous Program On Negotiation at Harvard Law School. We conclude with comments on the third chapter on mediation, in the third video clip presented by Professor Carrie Menkel-Meadow, who is the Distinguished and Chancellor's Professor of Law at UC Irvine and Emerita A.B. Chettle, Jr. Professor of Dispute Resolution and Civil Procedure at Georgetown University Law Center.
”Vi kan inte påstå oss vara feminister om vi inte tänker på hur vi pratar.”
Authors: Milles Karin
Published: June 2022

In recent years, the Swedish indefinite impersonal pronoun man has been replaced with en by feminist and norm-critical language users. This usage is an example of a burgeoning amount of Swedish feminist discursive work, and is in need of scrutiny and discussion. Through qualitative interviews with six users of the norm-critical pronoun en, the study seeks to understand its political potential and its limitations. The study concludes that the pronoun is used to advocate a more inclusive and gender neutral society, but that it also carries the potential to give its user a positive feminist identity. Furthermore, the study shows that pronouns also can work to exclude, and that users strategically adopt to this trait in their usage.
Overview of the Infection Control Prevention Program in the Internal Room of Aloei Saboe Hospital, Gorontalo City
Authors: Syukur Sabirin B , Asnawati Rini , Mustapa Moh. Sudirman , Binol Siti Rahma , Lajambu Nurdawati , Chatimah Ni’ma Chusnul , Laiya Nolva
Published: June 2022

Infection Prevention and Control (PPI) is an endeavor to prevent and reduce the incidence of infections among patients, employees, visitors, and members of the community in health care institutions. In order to reduce the occurrence of nosocomial infections, nosocomial infection control involves planning, implementing, monitoring, and encouraging. This study's objective was to characterize infection prevention and control in the interior chamber of Prof. Dr. Aloei Saboe Gorontalo City. This study employed a qualitative descriptive research approach with a random sample of 15 participants. The results indicated that the infection prevention and control program in the internal room had not been fully implemented, as 3 of the 15 participants did not practice proper handwashing (i.e., they did not follow the 6 steps outlined in the standard operating procedure), 1 participant did not use PPE during the procedure, but was able to apply coughing and sneezing etiquette, and 1 participant did not follow safe injection practices. Decontamination of equipment following completion of actions.
Pemberdayaan Anggota Karang Taruna melalui Pelatihan Pemanfaatan Limbah Plastik di Desa Sukoreno
Authors: Rofi Hidayah Anis , Nurpadilah Eva
Published: June 2022

Sampah plastik menjadi masalah dunia dan merupakan penyumbang kerusakan bumi yang paling utama. Kesadaran tentang pentingnya melakukan daur ulang serta upaya mengurangi penggunaan plastic telah gencar digalakkan oleh pemerintah dewasa ini. Akan tetapi pada ruang lingkup yang paling bawah yakni masyarakat desa, sosialisasi tersebut masih minim sekali. Pengabdian ini dilakukan bertujuan meningkatkan kesadaran warga Desa Sukoreno yang dalam hal ini anggota karang taruna untuk mengolah sampah plastic alih-alih hanya mengotori lingkungan. Penulis menggunakan metode penyuluhan dan pelatihan. Sasaran kegiatan ini adalah anggota Karang Taruna Desa Sukoreno. Tujuan dari pengbdian ini adalah pemuda desa yang tergabung dalam karang taruna memiliki pengetahuan tentang dampak sampah plastic yang tidak diolah serta memperoleh pengetahuan tentang peluang usaha yang dapat tercipta dari pemanfaatan sampah plastic.
Międzynarodowe wsparcie wojskowe Ukrainy
Authors: Piotrowski Sławomir
Published: June 2022

Od uzyskania przez Ukrainę niepodległości w 1991 roku dominującą cechą jej stosunków dwustronnych i wielostronnych jest współpraca w dziedzinie bezpieczeństwa z zachodnimi sojusznikami. W związku z aspiracjami Kijowa przystąpienia zarówno do UE, jak i NATO początkowa pomoc wojskowa dla Ukrainy koncentrowała się w dużej mierze na reformie systemu obronnego, planowaniu obronnym i budowaniu zdolności. W latach 1991–2014 wspomagano Ukrainę głównie na płaszczyźnie szkoleniowo-doradczej i poza nielicznymi wyjątkami pomoc ta nie dotyczyła dostaw sprzętu i uzbrojenia, z czym jest najczęściej kojarzona. Sytuacja zmieniła się po aneksji Krymu i wybuchu walk na wschodzie Ukrainy, jednak i wówczas niewiele państw zdecydowało się na udzielenie pomocy wojskowej. Niektóre państwa otwarcie zapowiedziały, że nie wyślą Ukrainie żadnego uzbrojenia, a inne zdecydowały się na przekazanie jedynie pomocy humanitarnej. Jako odpowiedź na aneksję Krymu przez Rosję w 2014 roku i trwający kryzys we wschodniej Ukrainie oraz na prośbę rządu ukraińskiego zachodni sojusznicy znacznie zwiększyli swoje wsparcie.
Forståelsen av lærerutdannerrollen blant skolebaserte lærerutdannere i Norge
Authors: Ivashenko Amdal Irina , Mastad Line Beate Tandsæther
Published: June 2022

I denne artikkelen undersøker vi praksislæreres forståelse av sin rolle som lærerutdannere. Denne kvalitative studien er basert på analysen av 104 refleksjonsnotater fra praksislærere ved fem lærerutdanningsskoler i Norge. Deltagerne ble bedt om å reflektere over sin rolle som lærerutdannere. Under analyseprosessen kom vi fram til at deltagerne i studien forstår sin lærerutdannerrolle som (1) portvoktere for- og ivaretagere av lærerprofesjonen, (2) veiledere og (3) relasjonsbyggere og rollemodeller. Vi diskuterer studiens resultater i lys av teori og tidligere forskning samt reflekterer rundt de etiske overveielsene som kan ha påvirket studiens resultater. Studien kaster et kritisk blikk på betydningen av en større involvering av praksisfeltet i profesjonskvalifiseringen av lærerstudenter.
Relación entre la actividad física moderada y el estrés académico en estudiantes universitarios
Authors: Cárdenas Calero Byron
Published: June 2022

El objetivo de este estudio fue analizar la relación la relación que existe entre la actividad física moderada y el estrés académico. La metodología fue no experimental del nivel descriptivo correlacional de corte transversal, se aplicó la técnica de la encuesta con un banco de preguntas validado a través de un juicio de cinco expertos su confiabilidad fue por medio del programa SPSS dando un alfa de Cronbach de 0.95. El instrumento fue enviado por Google Forms a 33 estudiantes universitarios pertenecientes a el octavo semestre de la Carrera Pedagogía en Actividad Física y Deporte. Los resultados indicaron que sí existe una relación significativa entre la actividad física y el estrés académico,  por lo que los estudiantes suelen eliminar el estrés cuando realizan algún tipo de actividad física moderada. Como conclusión. se manifiesta que al realizar actividad física puede mejorar los aspectos cognitivos de los estudiantes, como su concentración, mejorando su aprendizaje al eliminarse el estrés académico.
La gamificación en la matemática como herramienta potenciadora en el trabajo docente
Authors: Benítez Hurtado Ofelia Lorena , Granda Sivisapa Sonia Patricia
Published: June 2022

Esta investigación titulada: La gamificación en la matemática como herramienta potenciadora en el trabajo docente, empezó con un objetivo central, determinar la importancia que juega la actualización del profesorado de matemática en la incorporación de la gamificación en las prácticas didácticas de bachillerato. El enfoque fue cuantitativo, se aplicó dos encuestas: la una dirigida a 333 estudiantes y la otra a 14 docentes, pertenecientes a dos instituciones, seleccionados por muestreo aleatorio simple. En los resultados, se pudo determinar que entre los estudiantes de la Unidad Educativa A y B, predomina la aceptación de la herramienta Kahoot y Quizizz, a criterio de ellos, valoran positivamente la implementación de la mecánica del juego en la asignatura de matemática porque los anima a participar y los motiva a prender. De esta manera, se logró identificar que los docentes incorporan la gamificación en los dos grupos, propiciando muchos beneficios entre los más relevantes la atención, concentración y motivación en el estudiantado. En la conclusión, es fundamental seguir desarrollando las competencias digitales en los docentes de matemática que por premura propició la COVID 19 generando en los maestros esa actualización emergente y así poder atender las necesidades de los estudiantes.
La Actividad Física y su relación con el estrés laboral en los funcionarios del GAD parroquial de aloasi en el año 2021
Authors: GUACAPIÑA QUINALUISA JOAN
Published: June 2022

La presente investigación tuvo como objetivo principal determinar la relación que existe entre la de Actividad Física Moderada y el estrés laboral en funcionarios del Gobierno Autónomo Descentralizado parroquial Aloasi en el año 2021. La investigación es un estudio no experimental del nivel descriptivo correlacional de corte transversal, ya que se buscó determinar la relación que existe entre las dos variables objeto de estudio. La muestra fue de 35 personas y se utilizó la técnica de la encuesta, para obtener información acerca de los sujetos de estudio y como instrumento se aplicó un cuestionario sobre la relación entre la Actividad Física Moderada y El estrés Laboral. El análisis de datos se realizó mediante el programa estadístico SPSS v.22 donde al realizar la prueba de confiabilidad se obtuvo que el Alfa de Cronbach fue ∞= 0.861, también se utilizó las pruebas de Shapiro- Wilk (Prueba de normalidad) y la correlación de Spearman (No paramétrica). La investigación estableció que mediante la prueba de correlación de Pearson el p: (sig=0.206) es < 0.05 por lo cual acepta la hipótesis nula. No existe una relación significativa entre la Actividad Física Moderada y el estrés laboral en los funcionarios parroquiales.
Relación entre los estilos de vida y el rendimiento académico en estudiantes universitarios
Authors: Lara Inga Santiago
Published: June 2022

El objetivo de este artículo fue determinar la relación que existe entre los estilos de vida y el rendimiento académico de los estudiantes de 8vo semestre de la Facultad de Cultura Física, de la Universidad Central del Ecuador, periodo académico 2021-2021. El tipo de metodología utilizada fue descriptivo correlacional de corte transversal. Se aplicó la técnica de la encuesta y el instrumento que se seleccionó fue un cuestionario de tipo escala Likert. El análisis de los datos se realizó mediante el uso de estadísticas descriptivas en el programa SPSS. Se utilizó en su totalidad 30 alumnos del 8vo semestre. Al aplicar las pruebas estadísticas se encontró un P <0,05 lo que se interpreta que existen evidencias estadísticas que los estilos de vida que practica se relacionan significativamente con el rendimiento académico de los estudiantes quedando demostrada la hipótesis de investigación. Como conclusión, los estilos de vida saludables mejoran el desarrollo físico y cognitivo de los estudiantes universitarios, haciendo que lleven un aspecto físico adecuado y su aprendizaje en el aula sea significativo.
La arrancada movimiento clásico en halterofilia y la postura corporal en deportistas de 9 a 13 años
Authors: Macías Vera Tyrone , Aguas Liquinchana Mónica Gabriela , Liquinchana Muñoz Franklin , Saa Cedillo Mishel Dayana
Published: June 2022

Este estudio estableció la relación entre arrancada un movimiento clásico en el deporte olimpíco denomidado Halterofília y la postura en deportistas de 9 a 13 años de edad de la Escuela de Halterofilia de la Concentración Deportiva de Pichincha, se revisaron diversas refrencias bibliográficas, considerando artículos, libros y sitios web, principalmente en español, de diferentes países alineados al deporte como España, Colombia, Argentina, Cuba y México. Después de explorar el tema, se identificaron varios principios que pueden orientar la iniciación del deporte y la actividad física en los deportistas para un mejor desarrollo de su vida deportiva y recreativa, incluida la integridad adecuada de su condición física. La metodología aplicada utilizó un diseño correlacional transversal no experimental, con la implementación de una encuesta realizada a expertos observando a un grupo de 30 deportistas de 9 a 13 años de edad que asistían y entrenaban en la Escuela de formación de Halterofilia. El programa para poder analizar la correlación que se utilizó fue spsss statistics.
El rol del docente en el contexto universitario: una visión post pandemia
Authors: Posso Pacheco Richar Jacobo
Published: June 2022

La pandemia impactó de forma negativa en todos los ámbitos principalmente en lo económico, en la salud y en la educación; sin embargo, los docentes fueron los únicos que se beneficiaron debido a que se actualizaron en el uso y aplicación de nuevas tecnologías educativas, metodologías activas,  contextualizaciones curriculares y evaluaciones asertivas. El objetivo de este artículo editorial es plantear una visión post pandemia del nuevo rol que los docentes tiene que asumir y sus efectos en la formación de estudiantes universitarios. Mediante una investigación de tipo teórica se utilizará la técnica de análisis de contenido, con lo que se establecerá un entendimiento del camino pedagógico que se debe seguir alineado a los requerimientos de aprendizaje, en función a la satisfacción de demanda de profesionales que sean competentes en la sociedad del futuro.
PENGAJARAN TEKS NARATIF MENGGUNAKAN CERITA RAKYAT LOKAL: ANALISIS PENDIDIKAN KARAKTER, NILAI MORAL, DAN NILAI BUDAYA
Authors: Agustine Sherli
Published: June 2022

Penelitian ini bertujuan untuk mendeskripsikan prosedur pengajaran teks naratif menggunakan cerita rakyat lokal untuk mengetahui implementasi pendidikan karakter, nilai moral, dan nilai budaya dalam cerita rakyat Bawi Kuwu. Metode yang diguanakan adalah deskriptif kualitatif. Data dari penelitian ini berupa RPP dan teks cerita Bawi Kuwu. Hasil penelitian menunjukkan bahwa guru telah mengikuti RPP dalam proses belajar mengajar. Selain itu, nilai moral yang dapat dipelajari siswa dari analisis cerita Bawi Kuwu adalah hormat kepada orang tua, sabar, religius, jujur, patuh, peduli sosial, dan rendah hati. Sedangkan nilai budaya yang terkandung adalah adanya acara ritual adat Dayak para penganut kepercayaan Kaharingan. Dalam  cerita rakyat Bawi Kuwu terdapat implementasi pendidikan karakter yaitu tanggung jawab, kerja keras, keberanian, kesabaran, dan menepati janji. Penggunaan cerita rakyat dalam pengajaran naratif digunakan untuk meningkatkan motivasi siswa sebagai salah satu upaya untuk meningkatkan pendidikan karakter siswa dengan menggunakan budaya lokal dalam menghadapi era globalisasi.
USING MEDIA IN TEACHING ENGLISH OF ENGLISH TEACHER AT MADRASAH TSANAWIYAH NEGERI MODEL MAKASSAR
Authors: Pelu Hanafi
Published: June 2022

Penelitian ini bertujuan untuk menggambarkan dan mendeskripsikan cara Guru Bahasa Inggris menggunakan media di MTsN Model Makassar melakukan  proses  belajar-mengajar di kelas. Metode penelitian ini adalah penelitian kualitatif deskriptif dan studi kasus dengan desain. Subjek penelitian ini adalah dua guru bahasa Inggris yang mengajar di kelas tiga dan siswa kelas tiga dari dua kelas yang berbeda. Instrumen utama penelitian adalah peneliti itu sendiri. Dalam melengkapi data digunakan pedoman wawancara, dan catatan lapangan. Data dan sumber datanya adalah apa yang dilakukan guru di kelas mengenai pertanyaan penelitian. Data tambahan juga diambil dari siswa yang menggunakan wawancara. Teknik pengumpulan data yang digunakan adalah observasi, dokumentasi, dan wawancara. Temuan  penelitian mengungkapkan bahwa guru menggunakan berbagai macam media pembelajaran, yaitu; laptop, papan tulis, dan lembar kerja siswa.
The Rhetorical Infrastructure of Sexual Misconduct in Michigan State University’s Abuse Scandal
Authors: Koerber Amy
Published: June 2022

According to a December 21, 2018, Michigan Attorney General report, at least 105 Michigan State University employees, between 1997 and 2015, had received complaints from women about Dr. Larry Nassar’s inappropriate touching during medical treatment. In 2014, one of these complaints was finally reported to MSU’s Title IX office, triggering an investigation that led to a report that concluded Dr. Larry Nassar’s methods of treatment were “medically appropriate” and cleared him of any wrongdoing. Rhetorical analysis of this report exposes how Nassar benefitted from a rhetorical infrastructure that was designed to offer him institutional protection as an expert in medical techniques that require extensive touching of patients. Such analysis also exposes the specific discursive practices that sustain the rhetorical infrastructures that enable this institutional protection.
Childfree Sterilization: A Normative Rhetorical Theory Analysis of Paradoxical Dilemmas Encountered by Childfree Patients and Providers
Authors: Hintz Elizabeth
Published: June 2022

Abstract 
Guided by normative rhetorical theory, this study utilizes thematic analysis to explore narratives about sterilization consultations posted by childfree patients and medical providers to Reddit. This study explores the multiple meanings of sterilization, the paradoxical dilemmas competing conversational purposes create, and the communicative practices, interpretive lenses, and environmental resources patients and providers employ to manage dilemmas. The analysis reveals that voluntary sterilization inheres task, relational, and identity meanings for both patients and providers, creating paradoxical dilemmas and rendering sterilization consultations additionally challenging to navigate. Patients and providers both accept and confront paradox, adopt cultural and contextual interpretive lenses to evaluate others’ talk, and rely on childfree patient and physician social networks as environmental resources to shift the context in which talk occurs. The conclusion offers theoretical implications for normative rhetorical theory and practical implications, including: illuminating features influencing interactions in which sterilization requests are made and evaluated, and underscoring the multiple meanings that constrain patients and providers during these consultations.
The Politics of Standardized Patienthood
Authors: Press Sara
Published: June 2022

Abstract: Standardized Patient Programs (SPPs) enlist actors to roleplay the symptoms of various diseases and disorders, and to embody a range of personalities. These simulations are used to help improve the communicative practices and professional competencies of future healthcare workers. Focusing on the use of these programs for medical students and doctors, this article establishes a kairology of the SPP to better understand the shifting terrains of patient representation. A kairological account focuses on “historical moments as rhetorical opportunities” (Segal, 2005, p. 23) and, in the case of medicine, illustrates how “changes in [medical] practice are importantly reciprocal with changes in the terms of practice” (Segal, 2005, p. 22). I trace the SPP through various linguistic iterations to reveal how the shifting language of simulated patienthood reflects different orientations towards medical pedagogy and patient populations at significant junctures in time. I conclude my kairology with an examination of the Indigenous Simulated Patient Program, a 2011 pilot program that has the potential to better represent and serve Indigenous peoples in medical pedagogy and practice.
ПРИМЕНЕНИЕ МЕТОДОЛОГИИ ДИЗАЙН-МЫШЛЕНИЯ ДЛЯ РАЗВИТИЯ КОМПЕТЕНЦИЙ РАБОТНИКОВ ГОСУДАРСТВЕННОЙ СФЕРЫ
Authors: Петраускене Рута , Синкене Йолита , Даугелене Раса , Янюнайте Бригита , Вайчюнене Йоланта , Гайжюнене Лина , Штуопите Эдита
Published: June 2022

Дизайн-мышление — это творческая методология решения проблем, которая широко используется в различного типа организациях во всём мире. Основная цель данной публикации — помочь государственному сектору инновационно реагировать на вызовы и межсекторальные проблемы, с которыми сталкивается современное общество, и способствовать укреплению доверия к государственному сектору. Издание предназначено сотрудникам, руководителям организаций государственного сектора, студентам факультета социальных наук различного уровня подготовки, участникам программ неформального образования и всем, кто стремится творчески реагировать на любые вызовы и искать подходящие решения.
Agronomic Biofortification of Food Crops: A Sustainable Way to Boost Nutritional Security
Authors: Chaudhary Manoj , Mandal Abhijit , Muduli Soumyadarshi , Deepasree A. , Abshiba
Published: June 2022

After the green revolution, there has been a substantial increase in the productivity of food crops. But the nutritional aspect of crops could not keep pace with the growing demand of the population. This has led to a rise in malnutrition problems, especially in developing countries, due to a lack of balanced nutrition. Agronomic biofortification, the process of increasing micronutrient content in food crops through agronomic approaches, is seen as an important process to improve the status of malnutrition in the world. It is seen as a quick, safe, and cost-friendly approach to provide iron, zinc, and other micronutrients in our everyday diet. Unlike molecular/genetic approaches, agronomic biofortification is done on existing crops and varieties and hence the product is easily accepted by the consumers. Approaches like integrated nutrient management (INM) based on soil test values, microbial application, foliar spray of nutrients, can substantially increase the level of micronutrients, vitamins, folic acid, etc. in our food. With sufficient research interventions and awareness programs, agronomic biofortification can serve as a tool to improve the nutritional status of the world.
How Do Mouse Strains and Inoculation Routes Influence the Course of ExperimentalTrypanosoma cruziInfection?
Authors: de Oliveira Cardoso Flávia , Salles Domingues Carolina , Zaverucha do Valle Tânia , da Silva Calabrese Kátia
Published: June 2022

Chagas’ disease outcomes depend on several factors including parasite and host genetics, immune response, and route of infection. In this study, we investigate the influence of inoculation route and host genetic background on the establishment and development of Chagas disease in mice, using an isolate of Trypanosoma cruzi SC2005 strain (TcII), which was obtained from an oral Chagas’ disease outbreak in Santa Catarina, Brazil. Comparative analysis of the immunopathological, histopathological, and hematological profiles of mice was performed demonstrating the influence of the route of infection in disease severity. In outbred mice, intraperitoneal (IP) infection led to higher infection and mortality rates and more severe parasitaemia, when compared with intragastric (IG) infection. Nevertheless, tissue colonization was similar, showing severe damage in the heart, with intense lymphocytic inflammatory infiltrates, regardless of the route of infection. On the other hand, in mice IG-infected, the host genetic background influences the start timing of immune response against Trypanosoma cruzi. The susceptible BALB/c inbred mouse strain presented an earlier development of a cytotoxic cellular profile, when compared with A mice. We hypothesize that the cytotoxic response mounted before the parasitaemia increase allowed for a milder manifestation of Chagas’ disease in intragastrically infected mice.
Biosurfactant Production by Mycolic Acid-Containing Actinobacteria
Authors: M. Stainsby Fiona , Hodar Janki , Vaughan Halina
Published: June 2022

The Actinobacteria produce an array of valuable metabolites including biosurfactants which are gaining increased attention in the biotechnology industries as they are multifunctional, biorenewable and generally superior to chemically synthesized compounds. Biosurfactants are surface-active, amphipathic molecules present at the microbial cell-surface or released extracellularly and in a variety of chemical forms. The mycolic acid-containing actinobacteria (MACA), classified in the order Corynebacteriales, represent a potentially rich source of biosurfactants for novel applications and undiscovered biosurfactant compounds. Members of the mycolate genus Rhodococcus produce various well-characterised glycolipids. However, other mycolate genera including Corynebacterium, Dietzia, Gordonia and Tsukamurella although less extensively investigated also possess biosurfactant-producing strains. This chapter captures current knowledge on biosurfactant production amongst the MACA, including their chemical structures and producer organisms. It also provides an overview of approaches to the recovery of biosurfactant producing MACA from the environment and assays available to screen for biosurfactant production. Methodologies applied in the extraction, purification, and structural elucidation of the different types of biosurfactants are also summarised. Potential future applications of MACA-derived biosurfactants are highlighted with particular focus on biomedical and environmental possibilities. Further investigation of biosurfactant production by MACA will enable the discovery of both novel producing strains and compounds with the prospect of biotechnological exploitation.
Diagnosis and management of multiple salivary gland anomalies
Authors: Hamasaki Jean Teruo , Trentin Carolina Muniz , Pascoto Gabriela Robaskewicz , Araujo Melissa Rodrigues de
Published: June 2022

Anatomical anomalies in the salivary glands, such as ductal ectasia and stenosis, are rare and can be idiopathic, congenital, or acquired. The diagnosis of these anomalies is based on imaging examinations and is sometimes challenging. A 65-year-old female patient complained of a recurrent volume increase in the right preauricular region for 43 years. The swelling was exacerbated during the periprandial period. Physical examination with palpation revealed a flaccid swelling. Aspiration showed clear liquid compatible with saliva. Ultrasonography and magnetic resonance (MR) sialography showed changes in ductal anatomy and sialocele. MR sialography allowed the diagnosis of sialocele secondary to idiopathic duct anomalies, ectasia, and strictures in the parotid ducts. The treatment was sialoendoscopy. The patient presented a good clinical evolution with a significant reduction in swelling in the preauricular region due to less saliva accumulation. Sialoendoscopy is an effective method for the diagnosis and treatment of major salivary gland anomalies.
Dermoid cyst of the upper lip in a pediatric patient
Authors: Rodrigues Bruno Teixeira Gonçalves , Rio Maria Ivanda Rabelo do , Kuzsminszky Erika Castro , Romañach Mário José , Andrade Bruno Augusto Benevenuto de , Israel Mônica Simões
Published: June 2022

Introduction: Dermoid cyst (DC) is a slow-growing benign developmental cysts that arises from ectodermal tissue and can occur anywhere in the body, with only 34% occurring in the head and neck region, of which 6.5% are located in the mouth floor and rarely in the upper lip. It usually presents as painless, slow-growing lesion with doughy consistency and is often soft and well encapsulated - generally observed on the second to third decade of life. Objective: The objective of this article is to report a case of DC, focusing on its clinical and histopathological characteristics, and to discuss possible clinical presentations to assist in the diagnosis of this rare lesion in the oral cavity. Case Report: A 4-year-old female was referred for evaluation of an asymptomatic swelling in the left upper lip mucosa region lasting 1 year. Extraoral clinical examination showed no alterations. Intraoral clinical examination revealed the presence of a single painless well-defined nodular, sessile, non-tender swelling covered by normal oral mucosa, and located in the upper labial mucosa. An excisional biopsy was performed, and microscopic examination revealed a cystic cavity covered by orthokeratinized stratified squamous epithelium with hair follicles and sebaceous glands found within the fibrous wall. Patient recovery was uneventful and there are no signs of local recurrence in a two-year clinical follow-up. Conclusion: DC can occur anywhere in the body, but once in the oral cavity, it is rarely observed in the upper lip.
Timothy Jackson. Mordecai Would Not Bow Down: Anti-Semitism, the Holocaust, and Christian Supersessionism
Authors: Goldberg Sol
Published: June 2022

No abstract is available.
Las avenidas metropolitanas
Authors:   Universitat Oberta de Catalunya, Ortigosa Marín Javier , Pérez Pérez Maite , Pretel Fumadó Lluís
Published: June 2022

El desarrollo de infraestructuras viarias segregadas en el Área Metropolitana de Barcelona ha generado una gran demanda inducida de tráfico y las externalidades negativas asociadas a este. Además, ha condicionado la estructura urbana metropolitana y ha generado importantes barreras infraestructurales. Es tan necesario promover canales físicos prioritarios para la movilidad sostenible como articular la ciudad desde una escala más humana. En este artículo presentamos algunas de las iniciativas del Área Metropolitana de Barcelona (AMB) para conseguirlo, y en particular la red de avenidas metropolitanas como estructura para potenciar la movilidad sostenible y articular la ciudad metropolitana. Se explica la conceptualización de esta red y las implicaciones que esta tiene tanto en la escala de proximidad como en la escala metropolitana/regional con su coordinación con las vías segregadas.
Ways to develop tax incentives for greening of business in Russia
Authors: Samokhvalova Ksenia Vladimirovna
Published: June 2022

The article is devoted to the ecological aspect of the modern tax policy of the Russian Federation. The subject of this research is the instruments of state fiscal regulation aimed at encouraging companies to reduce their negative impact on the environment. The purpose of the study is to identify the possibilities of tax incentives for the greening of the economy and to develop recommendations for the further development of such tax instruments. The author analyzes elements of environmental taxation in Russian legislation and concludes that green transformation of business processes requires additional tax incentives. The research is based on general scientific methods of cognition, such as system and situational analysis, generalization, synthesis, logical and descriptive methods. The results of this research are the proposed tax measures to influence financial and economic activities of companies aimed at solving several key environmental issues. Free depreciation of best available technologies equipment will be an additional incentive to its implementation and will reduce the negative impact of production processes. Reduced VAT rate on goods made of recycled materials will lead to an increase in demand, popularization of such products and movement towards a circular economy. Preferential taxation of income from green bonds will contribute to the growth of investment attractiveness of environmental projects. Abolition of VAT restoring for food donations will reduce the cost of food sharing and the amount of food waste. Encouraging electronic document management through accelerated deduction of costs will conserve natural resources and minimize environmental damage. The evaluation of the proposed solutions showed their effectiveness and sources of compensation for the budgets of the budgetary system of the Russian Federation. They include growing tax base due to positive economic effects, the development of tax administration, environmental payments and carbon regulation, as well as a reduction in the required amount of government spending on several social items.
Experimental study on bulk modulus and dissipation of dry and wet granular samples under vertical vibration
Authors: Du Qing-Xin , Sun Qi-Cheng , Ding Hong-Sheng , Zhang Guo-Hua , Fan Yan-Li , An Fei-Fei ,   Department of Physics, University of Science and Technology Beijing, Beijing 100083, China,   State Key Laboratory of Hydroscience and Engineering, Tsinghua University, Beijing 100084, China
Published: June 2022

Dry granular materials are composed of a dense random packing of macroscopic grains. As a small amount of liquid is added to granular samples, the liquid bridge forces, i.e. the forces between liquid and the grains, have an influence on the mechanical properties of wet granular material, and some of these properties are quite different from those of dry granular materials. In this work, by measuring the acceleration of the sample chamber and the force exerted on it by the shaker, the variations of bulk modulus and energy dissipation of both dry and wet glass bead samples with pressure and viscosity under vertical vibration are studied. The results are shown below. 1) Under low saturation, the bulk modulus of dry and wet glass bead sample are both described by a power law scaling law with pressure, which is close to the power law relationship predicted by the efficient medium theory on the basis of Hertz contact potential. A small amount of liquid can increase the bulk modulus of glass bead sample. At the same pressure and liquid content, the bulk modulus of wet glass bead sample increases with liquid viscosity increasing. Based on Hertzian contact mechanics, an efficient elastic network model is proposed to illustrate the mechanism of increasing bulk modulus of wet glass bead samples. 2) The energy dissipation of dry and wet glass bead sample decrease following the power law of pressure, and the energy dissipation of wet glass bead samples is proportional to the kinematic viscosity of liquid. 3) With the increase of strain amplitude, the softening behavior of the wet glass bead sample is similar to that of the dry glass bead sample, when the strain amplitude is higher than the strain threshold value. The kinematic viscosity of liquid inhibits the softening behavior of glass bead sample.
Two-dimensional magnetic transition metal halides: molecular beam epitaxy growth and physical property modulation
Authors: Li Pei-Gen , Zhang Ji-Hai , Tao Ye , Zhong Ding-Yong ,   School of Physics, Sun Yat-sen University, Guangzhou 510275, China,   State Key Laboratory for Optoelectronic Materials and Technologies, Sun Yat-sen University, Guangzhou 510275, China
Published: June 2022

The spontaneous magnetization of two-dimensional (2D) magnetic materials can be maintained down to the monolayer limit, providing an ideal platform for understanding and manipulating magnetic-related properties on a 2D scale, and making it important for potential applications in optoelectronics and spintronics. Transition metal halides (TMHs) are suitable 2D magnetic candidates due to partially filled d orbitals and weak interlayer van der Waals interactions. As a sophisticated thin film growth technique, molecular beam epitaxy (MBE) can precisely tune the growth of 2D magnetic materials reaching the monolayer limit. Moreover, combining with the advanced experimental techniques such as scanning tunneling microscopy, the physical properties of 2D magnetic materials can be characterized and manipulated on an atomic scale. Herein, we introduce the crystalline and magnetic structures of 2D magnetic TMHs, and show the 2D magnetic TMHs grown by MBE and their electronic and magnetic characterizations. Then, the MBE-based methods for tuning the physical property of 2D magnetic TMHs, including tuning interlayer stacking, defect engineering, and constructing heterostructures, are discussed. Finally, the future development opportunities and challenges in the field of the research of 2D magnetic TMHs are summarized and prospected.
METTL18-mediated histidine methylation of RPL3 modulates translation elongation for proteostasis maintenance
Authors: Matsuura-Suzuki Eriko , Shimazu Tadahiro , Takahashi Mari , Kotoshiba Kaoru , Suzuki Takehiro , Kashiwagi Kazuhiro , Sohtome Yoshihiro , Akakabe Mai , Sodeoka Mikiko , Dohmae Naoshi , Ito Takuhiro , Shinkai Yoichi , Iwasaki Shintaro
Published: June 2022

Protein methylation occurs predominantly on lysine and arginine residues, but histidine also serves as a methylation substrate. However, a limited number of enzymes responsible for this modification have been reported. Moreover, the biological role of histidine methylation has remained poorly understood to date. Here, we report that human METTL18 is a histidine methyltransferase for the ribosomal protein RPL3 and that the modification specifically slows ribosome traversal on Tyr codons, allowing the proper folding of synthesized proteins. By performing an in vitro methylation assay with a methyl donor analog and quantitative mass spectrometry, we found that His245 of RPL3 is methylated at the τ-N position by METTL18. Structural comparison of the modified and unmodified ribosomes showed stoichiometric modification and suggested a role in translation reactions. Indeed, genome-wide ribosome profiling and an in vitro translation assay revealed that translation elongation at Tyr codons was suppressed by RPL3 methylation. Because the slower elongation provides enough time for nascent protein folding, RPL3 methylation protects cells from the cellular aggregation of Tyr-rich proteins. Our results reveal histidine methylation as an example of a ribosome modification that ensures proteome integrity in cells.
Omlegging til litteraturstudier på høyere utdanning
Authors: Folkman Anne Katrine , Haga Britt Marit , Josefsson Kristina Aareskoug
Published: June 2022

Denne artikkelen beskriver læring fra et pedagogisk endringsarbeid i høyere utdanning, ved omlegging til litteraturstudie av bacheloroppgaven, på to utdanninger våren 2021. Hensikten med denne fagartikkelen er å formidle pedagogiske og didaktiske erfaringer, og kunnskapsutvikling i omleggingsprosessen med relevans for andre utdanninger. I endringsarbeidet som presenteres er både studenters og underviseres læring i fokus, dette for å fremme både bedre utdanningskvalitet og livslang læring med betydning for profesjonell praksis.
Antispasmodics
Authors: Song Kyung Ho
Published: June 2022

Antispasmodics are effective in reducing abdominal pain associated with visceral organs, bloating, and bowel habit changes and are commonly used as “on-demand therapy.” A relatively regular intake of antispasmodics may help patients with functional gastrointestinal disease exacerbation. Irritable bowel syndrome and functional dyspepsia are representative functional gastrointestinal diseases with abdominal pain and bloating as the main symptoms. Most of the clinical data on antispasmodics are obtained from studies on functional gastrointestinal diseases including irritable bowel syndrome. Antispasmodics can be safely used for prolonged periods without serious adverse effects; however, different antispasmodics have different anticholinergic potencies. Antispasmodics with strong anticholinergic effects should be prescribed with caution to patients with glaucoma or prostatic hypertrophy-induced dysuria and to those driving vehicles, operating machinery, or receiving other anticholinergic drugs in combination. Antispasmodics meeting US Food and Drug Administration guidelines for efficacy, those showing relatively consistent efficacy in different trials, and those with prokinetic effects are currently available. Many patients with upper gastrointestinal symptoms have overlapping functional gastrointestinal disorders and may require antispasmodic drugs. Alternatively, tricyclic antidepressant or ramosetron use can be considered in patients with irritable bowel syndrome. This review summarizes the clinical data and characteristics of antispasmodics, particularly those available in South Korea.
Genetic diversity and demography of Bufo japonicus and B. torrenticola (Amphibia: Anura: Bufonidae) influenced by the Quaternary climate
Authors: Fukutani Kazumi , Matsui Masafumi , Tran Dung Van , Nishikawa Kanto
Published: June 2022

The Quaternary climate affected the present species richness and geographic distribution patterns of amphibians by limiting their activities during the glacial period. The present study examined the phylogenetic relationships of Japanese toads (Bufo japonicus and B. torrenticola) and the demography of each lineage from the past to the present based on mitochondrial sequences and ecological niche models. Japanese toads are a monophyletic group with two main clades (clades A and B). Clade A represents B. j. formosus, including three clades (clades A1, A2, and A3). Clade B contains three clades, two of which corresponded to B. j. japonicus (clades B1 and B2) and the other to B. torrenticola. Clade B2 and B. torrenticola made a sister group, and, thus, B. j. japonicus is paraphyletic. Clades A and B diverged in the late Miocene 5.7 million years ago (Mya) during the period when the Japanese archipelago was constructed. The earliest divergence between the three clades of clade A was estimated at 1.8 Mya. Clades A1 and A2 may have diverged at 0.8 Mya, resulting from the isolation in the multiple different refugia; however, the effects of the glacial climate on the divergence events of clade A3 are unclear. Divergences within clade B occurred from the late Pliocene to the early Pleistocene (3.2–2.2 Mya). Niche similarity between the parapatric clade in clade B (clades B1 and B2) indicated their allopatric divergence. It was suggested that niche segregation between B. japonicus and B. torrenticola contributed to a rapid adaptation of B. torrenticola for lotic breeding. All clade of Japanese toads retreated to each refugium at a low elevation in the glacial period, and effective population sizes increased to construct the current populations after the Last Glacial Maximum. Furthermore, we highlight the areas of climate stability from the last glacial maximum to the present that have served as the refugia of Japanese toads and, thus, affected their present distribution patterns.
Comparative study on intestinal microbiome composition and function in young and adult Hainan gibbons (Nomascus hainanus)
Authors: Li Yimeng , Bi Yu , Yang Liangliang , Jin Kun
Published: June 2022

The Hainan gibbon is one of the most endangered primates in the world, with a small population size, narrow distribution range, and high inbreeding risk, which retains the risk of species extinction. To explore the composition and functional differences of the intestinal microbiome of Hainan gibbons at different ages, the faecal microbiomes of young and adult Hainan gibbons were analysed using metagenome sequencing. The results showed that the dominant phyla in the intestinal tract of young and adult Hainan gibbons were Firmicutes and Bacteroidetes, and the dominant genus was Prevotella. Linear discriminant analysis effect size analysis showed that Firmicutes, Ruminococcus, Clostridium, and Butyrivibrio were significantly more abundant in adults than in young, whereas Bacteroidetes, Proteobacteria, Prevotella, and Bacteroides were significantly more abundant in young than in adults. In terms of gene function, the adult Hainan gibbon intestinal microbiome generally harboured a higher abundance of genes related to metabolic processes, such as carbohydrate, amino acid, and nucleotide metabolism. This may be due to adaptive advantages for adult Hainan gibbons, such as stable and mature intestinal microbiome composition, which allows them to utilise diverse foods efficiently. In summary, this study helps understand the dynamic changes in the intestinal microbiome of young and adult Hainan gibbons and plays a key role in the health monitoring and rejuvenation of their population.