bluuebunny/crossref_metadata_2025 huggingface dataset:
Effect of miR-27b-3p and Nrf2 in human retinal pigment epithelial cell induced by high-glucose
Authors:   Department of Ophthalmology and Optometry, Fujian Medical University, Fuzhou 350004, Fujian Province, China, Lai Qiao-Ling , Zheng Wei-Dong ,   The First Affiliated Hospital of Fujian Medical University, Fuzhou 350004, Fujian Province, China, Huang Yan ,   Department of Ophthalmology and Optometry, Fujian Medical University, Fuzhou 350004, Fujian Province, China
Published: September 2023

AIM: To determine whether the microRNA-27b-3p (miR-27b-3p)/NF-E2-related factor 2 (Nrf2) pathway plays a role in human retinal pigment epithelial (hRPE) cell response to high glucose, how miR-27b-3p and Nrf2 expression are regulated, and whether this pathway could be specifically targeted.
METHODS: hRPE cells were cultured in normal glucose or high glucose for 1, 3, or 6d before measuring cellular proliferation rates using cell counting kit-8 and reactive oxygen species (ROS) levels using a dihydroethidium kit. miR-27b-3p, Nrf2, NAD(P)H quinone oxidoreductase 1 (NQO1) and heme oxygenase-1 (HO-1) mRNA and protein levels were analyzed using reverse transcription quantitative polymerase chain reaction (RT-qPCR) and immunocytofluorescence (ICF), respectively. Western blot analyses were performed to determine nuclear and total Nrf2 protein levels. Nrf2, NQO1, and HO-1 expression levels by RT-qPCR, ICF, or Western blot were further tested after miR-27b-3p overexpression or inhibitor lentiviral transfection. Finally, the expression level of those target genes was analyzed after treating hRPE cells with pyridoxamine.
RESULTS: Persistent exposure to high glucose gradually suppressed hRPE Nrf2, NQO1, and HO-1 mRNA and protein levels and increased miR-27b-3p mRNA levels. High glucose also promoted ROS release and inhibited cellular proliferation. Nrf2, NQO1, and HO-1 mRNA levels decreased after miR-27b-3p overexpression and, conversely, both mRNA and protein levels increased after expressing a miR-27b-3p inhibitor. After treating hRPE cells exposed to high glucose with pyridoxamine, ROS levels tended to decreased, proliferation rate increased, Nrf2, NQO1, and HO-1 mRNA and protein levels were upregulated, and miR-27b-3p mRNA levels were suppressed.
CONCLUSION: Nrf2 is a downstream target of miR-27b-3p. Furthermore, the miR-27b-3p inhibitor pyridoxamine can alleviate high glucose injury by regulating the miR-27b-3p/Nrf2 axis.
Differential expression of antimicrobial peptides in human fungal keratitis
Authors:   Department of Ophthalmology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, Hubei Province, China, Wang Jia-Song , Zhao Zhao ,   Department of Ophthalmology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, Hubei Province, China, Wang Chao ,   Department of Ophthalmology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, Hubei Province, China, Xie Hua-Tao ,   Department of Ophthalmology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, Hubei Province, China, Zhang Ming-Chang ,   Department of Ophthalmology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, Hubei Province, China
Published: September 2023

AIM: To analyze a series of antimicrobial peptides (AMPs) in corneal tissue from individuals with fungal keratitis (FK) during the active phase of the fungus infection and after healing.
METHODS: Patients undergone lamellar keratoplasty for the treatment of severe FK or corneal scar had their corneal buttons sampled. Quantitative real-time polymerase chain reaction (PCR) was used to ascertain the gene expression of human beta-defensin (HBD)-1, -2, -3, -9, S100A7, 8, 9, and LL-37.
RESULTS: All AMPs’ messenger ribonucleic acid (mRNA) expression was considerably elevated in all samples (n=12). In contrast to controls, where HBD-2, -3, and S100A7 mRNAs were expressed at very low levels, it was discovered that HBD-1, -9, S100A8, S100A9, and LL-37 were constitutively expressed in all healed samples (n=4). HBD-1, -2 -3, S100A7, and LL-37 mRNAs were significantly increased in all active FK samples (n=8). The levels of HBD-9, S100A8, and S100A9 mRNAs were moderately upregulated in all active FK samples. Subgroup comparison showed that HBD-2 was significantly increased in Fusarium keratitis samples (n=5), and LL-37 mRNAs were significantly enhanced in Aspergillus keratitis samples (n=3). Whereas there was not significantly increased of HBD-1, -3, -9, S100A7, 8, 9 mRNA in Aspergillus keratitis samples compared with Fusarium keratitis samples.
CONCLUSION: AMPs expression is increased in active FK, but not all AMPs are equally expressed. HBD-2 and LL-37 expression levels are the highest, showing some specificity of AMP expression related to FK. Human AMPs, particularly HBD-2 may play a significant role in Fusarium keratitis and LL-37 might be the key player in Aspergillus keratitis.
Roda de conversa sobre saúde sexual e reprodutiva com adolescentes: um relato sobre dispositivos de cuidado em perspectiva dialógica
Authors: Soares Nogueira Rafael , De Almeida dos Santos Anna Bárbara , Da Silva Isabela , Lage Rodrigues Jaynni , Bussu Lima Denise , Serra Lazarini Welington
Published: September 2023

A adolescência desponta como uma das etapas mais importantes e desafiadoras do ciclo vital para se pensar a sexualidade. Dessa maneira, a criação de espaços de diálogo sobre sexualidade com os adolescentes deve contemplar temáticas que envolvam desde o descobrimento do próprio corpo, até o ato sexual em si. O objetivo é apresentar um relato de experiência sobre estratégias de promoção da educação sexual com adolescentes, a partir da vivência de um projeto de extensão. Trata-se de um relato de experiência sobre as ações de educação sexual para adolescentes da rede municipal de ensino fundamental, localizada na cidade de Vitória, capital do Espírito Santo. Diante dessa experiência extensionista na escola, consoante com o proposto pelo Programa Saúde na Escola, foi possível observar que durante os encontros os adolescentes se mostravam interessados em ouvir e participar das discussões, de forma que se propiciou um cenário favorável para a fluidez das conversas, tornando o ambiente confortável para que eles pudessem se expressar, sem medo ou vergonha, fazendo com que se sentissem parte ativa do compartilhamento de saberes, agregando suas vivências e opiniões.
Hazardous Impact of Coal Dust on Hematological Parameters of Underground Coal Mine Workers
Authors: Sultana Julekha , Paul Tiyesh , Banerjee Oly , Bhaduri Rama , Roy Soumya Sinha , Ghosh Suvendu , Bandyopadhyay Raktima , Mukherjee Sandip , Syamal Alak Kumar
Published: September 2023

Due to the nature of their work, coal miners have historically faced significant exposure to large amounts of dust, placing them at a heightened risk. The present study was conducted to explore the hazardous effects of inhalation of coal dust on the haematological parameters of underground coal miners. 120 underground coal miners (60 workers having 5-10 years of experience and the other 60 having 10-20 years of experience) and 62 matched non-exposed to coal dust subjects as control from the locality were recruited for the study. After obtaining consent, different physiological parameters were measured, and blood was collected for assessment of haematological parameters. Observations revealed that there were lower mean values of total RBC count, haemoglobin level, MCV, PCV, MCHC and MCH in coal mine workers whereas mean values of Red Cell Distribution Width (RDW) and ESR were increased in the workers group. Further, coal dust exposure causes increased total leucocyte to count as well as a differential count of lymphocyte, neutrophil, monocyte, and eosinophil in the workers group but, a decreased differential count of basophils was detected among coal dust-exposed workers. All the changes in haematological parameters were found to occur experience-dependent and maximum changes were observed in workers having 10-20 years of working experience. There is a significant likelihood of coal mine workers experiencing changes in their blood composition, which suggests the harmful impact of coal dust on this group. Further, haematological parameters will help health professionals to screen any pathologic conditions and may help to prevent coal dust exposure-associated haematological disorders and complications thereof.
Indian Entertainment Industry Analysis: Past, Present and Future
Authors: Jha Akash Kumar , Rayan Joseph Michael , Sanga Phillip M. Lairin , Babu R. Lokesh , Kumar Sravan
Published: September 2023

The entertainment industry is a component of the tertiary sector of the economy that includes the performing arts. When new technologies and concepts arise, the entire corporate world transforms. The industry is thriving financially and in terms of the talented artists and programmers it employs. Increased globalization and the subsequent elimination of market constraints resulted in astronomical growth. This research explores the origins, current conditions, hazards, potential solutions, future trends, and potential effects of foreign direct investment in India’s entertainment business. This research investigates the effects of globalization and its potential to provide new job possibilities. The data shown here has been gathered from secondary sources (the internet and published articles). The first form of entertainment was the transmission of cultural norms and beliefs from one generation to the next via the telling of stories. Since the arrival of the television triggered a seismic upheaval in the industry, distribution methods for entertainment have evolved gradually. While the epidemic has disproportionately affected certain areas of the industry’s workforce, others have been able to prosper because of the relative anonymity and safety of online venues. Television remains the most frequently consumed form of media, despite the advent of digital media and online gaming as more popular entertainment than film. As video streaming and other forms of online entertainment become popular, the OTT platform is anticipated to experience parabolic growth in the coming years. Due to the absence of references, the lack of emphasis on essential concerns, and the overall obsolescence of the accessible material, it was difficult to locate pertinent information. To support the nascent Indian entertainment industry and ensure the safety and stability of all its stakeholders, especially in challenging times like the ongoing pandemic, this paper highlights the significance of the government and regulatory bodies actively considering implementing incentive measures.
Two alphabets for one minority language as a threat to its existence (a case study of Lezgian)
Authors:   Linguistics University of Nizhny Novgorod, Shamilov Raviddin M.
Published: September 2023

The paper deals with the failed attempt of the Republic of Azerbaijan to introduce an additional Latin-based alphabet for the Lezgian language, which has been using the Cyrillic script since the late 30s of the 20th century to the present day. It provides a brief history of Lezgian script from ancient times to the present day, analyzes the current state and condition of Lezgian being spoken on the territory corresponding to its historical base – the Republic of Dagestan (Russia) and the Republic of Azerbaijan – and establishes its status as a minority and vulnerable language. With reference to the Latin-based alphabet of Lezgian which was in use from 1928 to 1938 and apparently has been offered as such in the Republic of Azerbaijan, linguistic disadvantages of the possible transition of Lezgian alphabet to the Latin script are revealed. The example of Lezgian suggests that an attempt by the state to provide a language which is recognized as a minority and, to some extent, even minorized language in it with an extra alphabet, as well as the lack of it at all, can be regarded as a real threat to the very existence of the language. The author concludes that despite the fact that there are a few other examples of biscriptalism represented by majority and official languages, to the development and existence of which the simultaneous use of another script in another country poses no threat, in case of Lezgian the biscriptalism could have a destructive impact on its development and cause social risks such as the loss of ethnic and cultural identity of Lezgian speakers, the division of the Lezgi people into two separate groups totally devoid of ethnic consciousness and their subsequent irreversible assimilation.
A “new woman” or a “superwoman”? A Silver Age project
Authors:   Lomonosov Moscow State University, Mikhailova Maria V. , Nazarova Anastasia V. ,   Lomonosov Moscow State University
Published: September 2023

The article analyzes literary texts and critical speeches of women and men-writers of the turn of the 19th – early 20th centuries, where the gender role models of the “new woman” and “superwoman” received the most vivid and original embodiment. Both models of femininity reflected the breaking of the usual gender order and the formation of a new system of values, in literature itself as well. The complex of feminist ideas associated with these types of models interested not only representatives of “high” literature. The creators of products for the mass reader, which absorbed both realistic traditions and the discoveries of modernism, also responded to the problem of women’s emancipation. N. M. Minsky in the play Alma and V. Bryusov in The Last Pages from the Diary of a Woman tried to present the model of the “superwoman” based on the Nietzschean vision. The field of activity for the “new woman” was outlined by E. A. Nagrodskaya and A. A. Verbitskaya in the novels The Wrath of Dionysus and The Keys of Happiness. Nevertheless, in all these works, the heroines failed, because they either became criminals, or faced an insuperable problem: actualizing the reproductive function or creative self-realization. Alma lost strength in the struggle for personal freedom, Bryusov’s Natalie became a murderer, Nagrodskaya’s Tatiana returned to the family shelter, Verbitskaya’s Manya, having achieved success in the art of ballet, committed suicide. And only M. Gorky in the novel Mother offered a solution: he put his Nilovna past the childbearing age and made her a freedom fighter for others. Thus, he managed to outline ways to rescue women from the snares of gender inequality. Nilovna can really be considered a “new woman”. And this utopian project turned out to be possible to implement in Soviet times by ignoring the real issues of gender controversies.
Spatial interactions in local public debt. Evidence from Poland
Authors: Banaszewska Monika
Published: September 2023

The aim of the paper is to investigate spatial interactions among the debt of 2,442 municipalities in Poland over the period 2005–2020. Using dynamic spatial Durbin model with two-way fixed effects it provides empirical evidence of positive spatial interactions. It is estimated that an increase in debt per capita in a given municipality by PLN 100 leads to an increase in the debt per capita in neighbouring municipalities by PLN 8–10. The result is robust to the various specifications of spatial weight matrix (contiguity vs. inverse-distance with a cut-off). It is also found that municipal debt in Poland suffers from high persistence over time.
Prospects for unique buildings construction and wood structures
Authors:   BMSTU (Mytishchi branch), Zaprudnov B.I. , Seregin N.G. ,   National Research Moscow State University of Civil Engineering, Potekhin N.I. ,   National Research Moscow State University of Civil Engineering
Published: September 2023

Projects of large-scale wooden buildings and structures are presented. The projects of buildings and structures erected using wood are analyzed. The main structural solutions based on wooden structures used in large-scale projects are considered. The most popular technologies for the production of wooden structures for unique construction are described. Based on the analysis of the projects of buildings and structures, it was concluded about the prospects for the construction of unique buildings and structures made of wood.
Biological activity of old-age cuttings cambisols in Western Caucasus
Authors:   Maikop State Technological University, Shkhapatsev A.K. , Kazeev K.Sh. ,   Southern Federal University, Kozun Yu. S. ,   Southern Federal University, Soldatov V.P. ,   Southern Federal University, Fedorenko A.N. ,   Southern Federal University, Kolesnikov S.I. ,   Southern Federal University
Published: September 2023

The peculiarities of ecological state and biological activity of soils in old-growth logging areas (500–700 m above sea level) in the West Caucasus in comparison with the soils of background forests in the Caucasus Biosphere Reserve were revealed. Vegetation of the control forest is represented by beech-fir-tree-tiered dead-grass forest, in cuttings aged 40–50 and 90–110 years the vegetation is represented by aspen-hornbeam honeysuckle-grass and beech-fir-tree-hornbeam small-grass forests. In terms of climate, relief, soil-forming rocks, and granulometric composition, the studied Cambisols are similar in their characteristics. Significant changes in some chemical and biological indicators were revealed in the Cambisols of background forest and cuttings with late stages of regenerative succession. The values of the integral index of the biological state of Cambisols for cuttings of different age calculated according to 9 different indices are 100 and 98 % and significantly exceed the control values (77 %) of soils of the control forest. The reasons for this lie in the greater diversity and productivity of the vegetation ground cover, leading to the activation of biological processes in Cambisols.
Assessment of aviation protection works on lands of protected areas of Federal significance
Authors:   All-Russian Scientific Research Institute for Forestry and Forestry Mechanization, Korshunov N.A. , Savchenkova V.A. ,   All-Russian Scientific Research Institute for Forestry and Forestry Mechanization; 2BMSTU (Mytishchi branch), Perminov A.V. ,   All-Russian Scientific Research Institute for Forestry and Forestry Mechanization, Konyushenkov M.E. ,   All-Russian Scientific Research Institute for Forestry and Forestry Mechanization
Published: September 2023

The assessment of air protection works on the lands of specially protected natural territories is presented. The disadvantages of aviation forest monitoring are considered. The analysis of the actual fire danger of forests on the lands of specially protected natural territories is carried out. To assess the risks of 111 specially protected natural territories for the period from 2002 to 2021, a retrospective analysis of the registered thermal points in the systems of space monitoring of forest fires of the information system of remote monitoring of Rosleshoz (ISDM-Rosleshoz) and FIRMS was made. The absence of fires in certain periods does not exclude the risks of their occurrence. Based on the analysis of thermal points, the predominance of spring fires was revealed. The description of the areas characterized by the occurrence of fires depending on the season of the year is given. The result of the analysis of the situation with the occurrence of forest fires on the lands of specially protected natural territories in the context of federal districts is presented. During the study of the forest protection system on the lands of specially protected natural territories, an expert assessment of the organizational structure, forms and composition of fire extinguishing teams, as well as the availability of fire extinguishing forces and means was carried out. The structure of forest fire formations, a communication and warning system for ground and aviation forces are analyzed. An expert assessment of the effectiveness of air patrol routes on the lands of specially protected natural territories was carried out. The problem of remoteness of aircraft bases has been identified. Solutions to problems for areas with low and high burnability are proposed. The problem of the absence of an approved unified methodology for assessing the probability of landscape (natural) fires on lands of other categories, from the territory of which there may be a threat of fire transfer to the lands of specially protected natural territories, is revealed. Proposals have been developed for the formation of optimal patrol routes for manned and unmanned aircraft
Features of fire season 2022 in Kurgan region
Authors:   FBU «Avialesookhrana», Eritsov A.M. , Sekerin D.M. ,   Ural State Forestry Engineering University, Krektunov A.A. ,   Ural Institute of the State Fire Service of the Ministry of the Russian Federation for Civil Defense, Emergencies and Disaster Relief, Zalesov S.V. ,   Ural State Forestry Engineering University
Published: September 2023

On the basis of a comprehensive analysis of the weather conditions, the necessary extinguishing equipment provided and the additional forces and means involvement, the dynamics of the number of forest fires with the area covered during the fire season have been shown in the article. It was established that in 2022, 468 forest fires were recorded in the forest fund of the Kurgan region and their area was 123 709,48 ha. Thanks to the involvement of additional forces and fire extinguishing equipment, despite adverse weather conditions, it was possible to reduce the number of forest fires by 2,8 times compared to 2021 and reduce the number of large fires by 2 times. At the same time, in 2022 an increase in the area covered by fires and the average area of forest fires were recorded. It has been established that in the region there is a tendency to increase the burning of the forests which necessitates more strict control over compliance with fire safety rules. It is recommended to timely introduce a regional emergency mode and more quickly maneuver the fire forces and means. Taking into account that the part of the forest fund part is contaminated with radionuclides as well as swampiness, it is recommended to use aviation forces and means more widely in protecting forests from fires.
Groups of ornamental perennial culture herbaceous plants according to vegetative mobility degree
Authors:   Nizhny Novgorod State University of Architecture and Civil Engineering (NNGASU), Lavrova O.P.
Published: September 2023

The division of ornamental herbaceous plants of perennial culture into groups according to the degree of vegetative mobility is proposed. Based on the distance by which the renewal buds move away during the growing season, it is proposed to distinguish the following groups: vegetatively-stationary (the kidneys move away no more than 3 cm; vegetatively-sedentary (at a distance of 3 to 10 cm); vegetatively-mobile (from 10 to 30 cm); vegetatively aggressive (more than 30 cm). A review of the collection of ornamental herbaceous plants according to the degree of their vegetative mobility is made and examples of plants for each group are given. Recommendations on the content of such plants in flower compositions, the economic efficiency of keeping plants from different groups according to the degree of vegetative mobility in flower beds are considered.
NEORREGIONALISMO COMO UMA ESTÉTICA CULTURAL
Authors: Lira Rhusily , Brito Herasmo Braga de Oliveira
Published: September 2023

O neorregionalismo brasileiro se caracteriza como uma continuidade do regionalismo brasileiro, entretanto, com configurações que se alinham ao tempo contemporâneo. Assim, o presente estudo tem como objetivo discutir o neorregionalismo e os traços do regionalismo como uma estética cultural que abrange diversas manifestações artísticas, neste artigo focaremos na narrativa literária de Francisco Dantas, especialmente em Coivara da memória (1996) e as narrativas pictóricas do regionalismo e neorregionalismo. Utilizaremos como aporte teórico Antonio Candido (2008); Gilda de Mello e Souza (2008); Aracy Amaral (2006), entre outros.
Teoria niesprawiedliwości J. S. Adamsa
Authors: Michałkiewicz Anna
Published: September 2023

This paper explores J. S. Adams’ inequity theory. It discusses fundamental concepts, the definition of the sense of equity and inequity, possible consequences and methods of coping with them. It elaborates on the problems connected with measurement methods used to evaluate the sense of inequity as well as possible practical applications of the theory. The paper comprises also a review of the most important research in the field.
Czynniki społeczne w genezie nieprawidłowego rozwoju i zachowania
Authors: Siwek Stanisław
Published: September 2023

The paper deals with the impact of the social background for developmental disorders, searching for unfavorable factors in the three most important surroundings – family, school, contemporary group. Hence the analysis was made with signs of improper interpersonal relations and life conditions encroaching on mental balance that can be found in social agencies (school, family), responsible for personal development and behavior. Basing upon selected theoretical works and my diagnostic and therapeutic experience, various negative effects on personal development were illustrated, given the ill-adapted familial and educational systems, as well as informal roles played in contemporary groups. The paper got its material focused on the familial environment where personality traits and parental attitudes, ways of communication and pathological mechanisms permanently generate factors that appear unfavorable for personal social development (toxic messages, enforced loyalty, role delegation,collusion relationships). A particular emphasis was put on the role of social factors in the origins of both primary and secondary disorders, and on the fact that signs of difficulties and disorders a youngster meets may be an indirect reaction to factors infringing on his/her psychological balance or else – actualized belatedly when assuming new social roles.
Ewolucja form pracy i zmiany na rynku pracy a wynikające z nich zadania dla psychologów
Authors: Hauk Mateusz
Published: September 2023

The aim of this article is to describe the changes on the job market that have been taking place recently (especially the increasing number and growth of popularity of alternative work arrangements, such as: part time employment, contingent employment, flextime, compressed work weeks and teleworking), and their consequences. Working with nonstandard work arrangements have a great impact on employees (e.g. increasing flexibility connected with work-family interference, workaholism, problems with creating self-concept in the field of work) and employers as well (work decentralization, the growth of popularity of team working, the need to manage the information, the diversity in the organization etc.). In the result there is a strong need to verify and extend the tasks of industrial and organizational psychology and the practice of applied psychologists. This article outlines new demands from the job market and new tasks for the work psychologists.
La forestería y su relación con el otro-que-humano
Authors: Arce-Rojas Rodrigo Severo , Yábar-Torres Guisela
Published: September 2023

El presente artículo tiene como propósito establecer las relaciones entre la forestería y el otro-que-humano desde el enfoque de la complejidad, a su vez enriquecer el marco teórico y las prácticas de la forestería trascendiendo el enfoque estrictamente antropocéntrico. De la revisión, reflexión y análisis se encuentra que las ciencias de la complejidad, por tener una orientación más clara de la comprensión de la vida en general, amplifican el campo de visión de la forestería para el reconocimiento del valor intrínseco del otro-que-humano en los bosques. Aunque de manera institucional, el SERFOR mantiene la lógica de recursos forestales con orientación productiva, en su estructura existe un buen marco de respeto al otro-que-humano de los bosques. Esta lógica no guía la concepción y práctica de los profesionales forestales que en un porcentaje considerable todavía mantienen una concepción fuertemente utilitarista y productivista.
Numerical solution features of Maxwell equations by FDTD method in the homogeneous and nonhomogeneous formulations
Authors: Makarov P. , Ustyugov V. , Scheglov V.
Published: September 2023

In this paper we investigate the features of the numerical

FDTD solution of Maxwell’s equations formulated as Cauchy

problems for the corresponding homogeneous and inhomogeneous

systems of equations. It is shown that for the case

of time-limited field sources the Cauchy problem for an inhomogeneous

system is equivalent to the corresponding Cauchy

problem for a homogeneous system. The criterion for evaluating

the correctness of the obtained solution is defined. The

features of the numerical solution of homogeneous and nonhomogeneous

Cauchy problems for different forms of initial

configurations of electromagnetic fields and setting pulses

are analyzed. Necessary and sufficient conditions of correctness

of the obtained solutions are formulated.
Multivariate Modeling of Design Parameters of Elastic Clips of Modern Rail Fasteners, with Analysis of Their Stress-Strain State
Authors: Karyukin Maksim
Published: September 2023

Purpose: To determine the influence of geometric parameters on the most common elastic rod clip used in modern intermediate rail fastenings — the B-shaped clip (such as reinforced concrete rail (RCR) clip and anchor rail fastening (ARF)) — on changes in its stress-strain state. To propose a further direction of improving the design of elastic rod clips of rail fasteners to increase the reliability of the structure. Methods: The article presents the results of multivariate modeling of the geometric parameters of the clips (RCR — 20 pcs., ARF — 13 pcs.) with the analysis of their stress-strain state, using the methods of software and computer systems SolidWorks and Ansys Workbench. Results: Analysis of the design of modern fasteners has shown that the intervals for varying the geometric parameters of the clips (rod diameter, vertical radius, horizontal radius) have small limits and significant limitations associated with the requirements for ensuring the strength, elasticity and operability of the entire fastening. The necessity of considering options with vertical radii less than 60 mm has been revealed, which entails the need for a radical change in the shape of the clips themselves. Practical significance: As a result of the analysis of the calculations of multivariant models, the degrees of influence of the intervals of variation of the geometric parameters of rod clips (rod diameter, vertical radius, horizontal radius) on the stress-strain state have been determined. It is established that in order to further increase the elasticity of the clips, it is necessary to develop a new type of rail fastening with a fundamentally different shape (different from the modern B-shaped) elastic clip that does not have modern design limitations in geometric parameters.
The Use of Dynamic Vibration Dampers to Increase the Stability of Tower Communication Structures under Wind Loads
Authors: Bogdanova Galina , Ivanova Zhanna
Published: September 2023

Purpose: To investigate the application of dynamic vibration dampers in communication tower structures to protect them from the effects of wind loads. Methods: To analyze the design features of existing tower structures. To consider the effect of various factors including wind loads on the choice of tower structure design. To analyze the climatic parameters of the construction area and to determine the type of tower structure as the subject for conducting this research. To determine the quality criteria of vibration damping, on the basis of which the selection of design dynamic vibration dampener (DVD) construction is carried out, and to calculate its weight. To conduct the calculation study of the selected type of building with regard to wind loads and evaluate the effectiveness of the proposed solution of the dynamic vibration dampener to increase the stability of communication tower structures in areas with wind gusts over 25 m/s. Results: The results of the research of dynamic vibration dampener design aimed at improvement of operating conditions of telecommunication facilities in the areas with increased wind load are presented. Practical significance: It is shown that the use of dynamic vibration dampers in tower constructions of cellular communication makes it possible to reduce the vibration amplitude and the maximum horizontal displacements occurring in the tower structure under wind load.
Application of the Internet of Things Technology for Data Transmission from an Automatic Grounding Resistance Meter
Authors: Evdokimova Ol'ga , Kucenko Sergey , Meshkov Bair
Published: September 2023

Purpose: To organize operational automatic monitoring of the real state of one of the important technical elements of the Directorate of Communications and the Directorate of Infrastructure of JSC “Russian Railways” — of the grounding systems for communication, signaling, centralization and blockage (SCB). Methods: Comparative analysis of the technical characteristics of devices existing in the relevant telecommunications equipment market that implement the Internet of things technology and standard switching solutions for various devices with a unified monitoring and administration system (UMAS). Results: An optimal solution has been obtained for collecting and automatically transmitting information of such a parameter as the electrical resistance of the grounding device. A technical solution is proposed that allows to coordinate the collection of information by means of necessary sensors used in the implementation of the Internet of Things technology, network equipment and the transmission of information to the UMAS by means of a modular diagnostic complex and transmitting devices (switching equipment and multiplexers) provided by LLC “Pulsar-Telecom Design Bureau”. Practical significance: A comprehensive solution for collecting, transmitting and monitoring the condition of the object is proposed, which allows to respond promptly to changes in such an important parameter as the resistance of the grounding device in order to plan the activities of repair, operational and restoration teams and other services of enterprises of the directorates of communications and infrastructure. A comparative analysis of three technologies of the Internet of Things — LoRaWAN, NB-IoT, STRIZH, allowing to assess the advantages and disadvantages of each in achieving the goal.
The Methodology for the Formation of a Comprehensive System of Synchronization and Delivery of the Time Scale for a Large-Scale Distributed Technological Purpose System
Authors: Oparin Evgeniy
Published: September 2023

Purpose: To develop scientific and technical solutions for constructing a comprehensive synchronization system and delivery of the time scale, which includes subsystems of network clock synchronization (NCS) and unified time (UT), as a unified timekeeping system addressing the challenges of frequency, time, and phase synchronization in large-scale distributed technological purpose systems. Methods: Research methods are based on the fundamental provisions of the theory of systems and the theory of decision-making. Results: A methodology for the formation of a comprehensive synchronization system and the delivery of a time scale is proposed, which is characterized by an integrated approach to building unified time and frequency systems in the communication networks of the technological segment, the independence of the types of generator equipment used and the means of delivery of NCS and UT signals, as well as meeting the requirements of potential consumers of frequency and time services. The proposed methodology for the formation of a comprehensive synchronization system and delivery of a time scale will allow to reasonably approach building systems for delivering unified time and frequency signals in complex heterogeneous communication networks. Practical significance: Solutions based on the presented methodology will allow the provision of an infrastructure independent of external communication operators to ensure the unity of network clock synchronization and unified time. This is necessary for the correct operation of telecommunication equipment of the technological communication network. The methodology will also meet the needs for providing a full range of synchronization and unified time signal services to existing and prospective consumers. Additionally, it will enable a gradual transition of the organization of communication networks from channel-swithching to packet-oriented technologies due to a flexible approach to the routes and transmission systems used for the distribution of synchronization signals and unified time.
CORRECTING STUDENTS CORRECTLY: AVOIDING GRAMMAR MISCONCEPTIONS IN THE FOREIGN LANGUAGE CLASSROOM
Authors:   Associate Professor of English, Hankuk University of Foreign Studies, Seoul, South Korea, Hull Todd
Published: September 2023

Grammatical accuracy is a justifiable goal in language teaching classrooms. But misconceptions about grammar can hinder this goal. The main misconception is that native speakers make grammar errors when using their own native language. They do not. The idea that native speakers can make grammar mistakes in their own languages is detrimental to foreign language classrooms because when language teachers attempt to find answers to grammar questions, they encounter conflicting information and are sometimes not able to give their students useful answers. The main cause of the misconception that native speakers can make grammar errors in their own language is the conflation of formal and informal style, a conflation of grammar and style, which leads to informal usage being incorrectly stigmatized as incorrect grammar. This paper will outline three major misconceptions arising from this fundamental confusion of style and grammar: 1) the idea that native speakers use words incorrectly; 2) native speakers using words that are said not to be real words; and 3) conflation of emphasis and redundancy. This issue will be addressed in the context of the English language. But the principles apply across languages. Knowledge of these misconceptions will allow language teachers to answer and advise students.
Relación entre sobrecompromiso y síntomas somáticos en enfermeras de un hospital de II nivel en Perú
Authors: León Sara , Núñez Manuel , Chilca Manuel
Published: September 2023

Objetivo: Determinar la relación entre sobrecompromiso y síntomas somáticos en enfermeras de un hospital de II nivel en Perú. Material y métodos: Investigación observacional, transversal y correlacional, con una muestra probabilística de 106 enfermeras. Se aplicó el Cuestionario de Siegrist y Meter para medir sobrecompromiso y desequilibrio esfuerzo recompensa, y el Cuestionario de Salud (PHQ15) para síntomas somáticos. Se construyó un modelo de regresión logística, considerando variables sociodemográficas y laborales. Resultados: En las enfermeras que presentaron síntomas somáticos moderados-graves, el 68,3% tuvo un nivel de sobrecompromiso alto. El modelo de regresión mostró que sobrecompromiso (OR = 6,25, p < 0,01), tiempo laboral (OR = 0,74, p < 0,01) y la condición de personal (nombrado o contratado, OR = 49,20, p < 0,01) influyeron en el nivel de síntomas somáticos. El modelo discriminó correctamente el 79% (IC 95%: 0,70 – 0,88) de los casos con síntomas somáticos, siendo el valor 0,43, el que se usò para la clasificaciòn en leve-mìnimo y moderado-grave con una sensibilidad de 73% y especificidad del 74%. Conclusión: Se corroboró una relación significativa entre sobrecompromiso y síntomas somáticos, con un modelo predictivo que logró un nivel elevado de discriminación para identificar personal de enfermería en riesgo.
Factores relacionados con la adherencia al tratamiento de rehabilitación de los pacientes con Diabetes Mellitus tipo 2 con amputación de miembro inferior
Authors: Villegas Flores Lourdes
Published: September 2023

Objetivo: Determinar los factores clínicos y sociodemográficos relacionados con la adherencia al tratamiento de rehabilitación de los pacientes con Diabetes Mellitus tipo 2 con amputación de miembro inferior. Material y métodos: Estudio observacional, retrospectivo, comparativo y relacional; se incluyeron 113 pacientes con DM tipo 2 del Departamento de Investigación, Docencia y Rehabilitación Integral en Amputados, quemados y Trastornos Posturales del Instituto Nacional de Rehabilitación “Dra. Adriana Rebaza Flores” AMISTAD PERÚ – JAPÓN, que ingresaron en el periodo 2016 al 2019. Se recolectaron variables sociodemográficas y clínicas; y para la adherencia al tratamiento de rehabilitación se consideró la asistencia de los pacientes a 5 áreas de atención en salud, y el alta de prótesis de los pacientes. Resultados: El 75,52 % de pacientes fueron del sexo masculino, con edad media de 66,6 ± 12,1; y la media del tiempo de alta de prótesis fue 11,4 ± 6,75 meses. Se encontró diferencia significativa entre adherencia y no adherencia en la edad, nivel socioeconómico, estado civil y cobertura de atención (p < 0,05)   Conclusiones: La mayoría de los pacientes amputados con DM tipo 2 fueron del sexo masculino cuyo cumplimiento o adherencia a la rehabilitación se relacionó con factores sociodemográficos como la edad, estado civil, nivel socioeconómico y cobertura de salud.
MATERNAL DEATH DETERMINANT AND HEALTH SERVICE DELIVERY DURING COVID-19: WHAT'S THE DIFFERENCE?
Authors: Ainul Yaqin Moch Jazil , Prasiska Danik Iga , Fatah Nur Aini
Published: September 2023

Background: The COVID-19 pandemic has provided a new challenge for the delivery of health system in Indonesia. Maternal health services were no exception, as the reduction in antenatal unscheduled home visits were the main issues found in maternal health service disruption during the COVID-19 pandemic. In the last few decades, Indonesia has adopted a range of health strategies to reduce maternal mortality rates. Nganjuk is one of the regencies that enforce the reduction of maternal mortality, which successfully reducing maternal mortality rates from 212 per 100.000 live births in 2010 to 57 per 100.000 live births in 2018. With the emergence of COVID-19, the health system’s capacity and access are once again being shaken. Purpose: This research aimed to analyze the determinants of maternal death before the COVID-19 pandemic situation and during the COVID-19 pandemic. Method: This type of research is non-reactive research using secondary data from maternal mortality reports, Nganjuk Regional Health Office. Analysis was carried out with a chi-Square test using Statistical Package for the Social Sciences (SPSS) version 26.0. Results: A significant increase in maternal deaths (85.29%) was observed during the COVID-19 pandemic. Determinants of maternal death, such as the age of the mother (p<0.00), number of pregnancies (p<0.00), period of death (p=0.02), healthcare referral (p=0.01), and cause of death (p<0.00) showed a significant increase during COVID-19. Conclusion: COVID-19 pandemic contributed to the increase in maternal deaths in Nganjuk Regency. This study has implications for the priority setting in policy development and implementation at reducing maternal mortality.
CASE STUDY OF HOST AND ENVIRONMENT FACTORS ON DHF INCIDENCE IN LIMA PULUH DISTRICT
Authors: Ginting Tarianna , Pane Putri Yunita , Pakpahan Eka Lolita Eliyanti , Gultom Dameria , Indriyani Sari
Published: September 2023

Background: In the last fifty years, dengue hemorrhagic fever (DHF) has increased 30 times in 100 endemic countries. As a tropical country, Indonesia is one of the endemic countries for DHF cases, which often cause "extraordinary events". Purpose: This research aims to analyze the factors contributing to DHF, including individual and environmental factors. Methods: In November 2022, the unmatched case-control research method was retrospectively used. All DHF cases in Lima Puluh District between January and August 2022, totalling 26 cases, made up the population of this study. The sample in this study was taken based on the total sampling method. The sample consisted of 26 respondents in the case group (those affected by DHF) and 52 respondents in the control group with inclusion criteria (not affected by DHF, distance from house ± 50 meters, age criteria, sex according to the case group) and exclusion criteria (not willing to be a respondent, not in place). The total sample size is 78 respondents, consisting of 26 respondents in the case group and 52 respondents in the control group, with a ratio of 1:2. Results: Based on the results of the chi-square analysis conducted. There was no significant relationship between gender (p = 0.09) and the habit of hanging clothes (p = 0.06) with the occurrence of DHF in Lima Puluh District in 2022. The results of the logistic regression test stated that all host and environmental factors did not have the most dominant variable in the incidence of DHF in Lima Puluh District in 2022. Conclusion: The variable of the existence of breeding places is a dominant factor in the occurrence of DHF in Lima Puluh District in 2022.
Motivasi Belajar dalam Mengikuti Pembelajaran Daring Siswa Kelas X SMA
Authors: Wardhana Damara Putri , Hidayat Rian Rokhmad , Purwaningrum Ribut
Published: September 2023

This study aims to analyze the level of learning motivation of class X, differences in learning motivation between male and female and differences in motivation learning between students majoring in science and social studies, difference in scores between before online learning and after online learning at SMAN 2 Surakarta. This study uses a quantitative research approach with survey research methods. The sample in this study was 190 students of class X at SMAN 2 Surakarta with non- probability sampling technique. Data collection techniques using a questionnaire. The data analysis in this study used descriptive analysis, independent sample t-test and paired sample t-test. The results of this study indicate that (1) the students of class X at SMAN 2 Surakarta have moderate learning motivation, (2) there is no significant difference between the learning motivation of male students and female students, (3) no significant difference was found between the learning motivation of students majoring in science and students majoring in social studies, (4) no significant difference was found between student learning outcomes before online learning and after online learning.
Countering Mpox Vaccination Disparities in Los Angeles County, California, May–December 2022
Authors: Brihn Auguste , Yeganeh Nava , Kulkarni Sonali , Moir Olivia , Madrid Saloniki , Perez Mario , Singhal Rita , Kim Andrea A.
Published: September 2023

Providing equitable access to vaccines for individuals at risk for mpox was critical for containing the 2022 mpox outbreak in Los Angeles County, California. Eligible non-Hispanic Black/African American and Latinx individuals had lower vaccine uptake than did non-Hispanic White individuals, despite having higher mpox case rates. Strategies to address disparities in vaccine uptake included using familiar messaging technology to reach individuals at risk for mpox, using partnerships with community-based organizations to raise mpox awareness, and bringing vaccines to locations convenient to at-risk individuals to improve access. (Am J Public Health. 2023;113(12):1258–1262. https://doi.org/10.2105/AJPH.2023.307409 )