bluuebunny/crossref_metadata_2025 huggingface dataset:
High Olfactory Receptor-Rich 11q11 Copy Number in Girls and African American Children
Authors: Phillips Megan , Selvaraju Vaithinathan , Fouty Anna , Babu Jeganathan Ramesh , Sandey Maninder , Geetha Thangiah
Published: December 2021

Copy number variants (CNVs) provide numerous genetic differences between individuals, and they have been linked with multiple human diseases. Obesity is one of the highly heritable complex disorders, which is associated with copy number variance (CNV). A recent report shows that the 11q11 gene, a novel olfactory receptor, and its copy number variants are involved in the early onset of obesity. In the current study, we analyzed the 11q11 gene copy number variance (CNV) based on gender in White/European American (EA) and African American (AA) normal weight and overweight/obese children. Sixty-nine boys and fifty-eight girls between the ages of 6 and 10 years belonging to either EA or AA ethnicity were involved in this study. As per World Health Organization (WHO) guidelines, each participant’s body weight and height were recorded. DNA was extracted from saliva, and the copy number variants for the 11q11 gene were measured using digital PCR. The descriptive analysis of the 11q11 copy number showed significantly more copies in girls compared to boys; similarly, AA participants had significantly increased CNV compared to EA. The normal weight (NW) and overweight/obese (OW/OB) girls were significantly less likely to belong to the low copy number variant (LCNV) group of 11q11 compared to boys; similarly, NW and OW/OB AA children were significantly less likely to belong to the LCNV group. The AA girls in LCNV had significantly higher BMI z-scores. Our findings suggest that the 11q11 copy number in children is race and gender-specific.
Transatlantic Lifelines: Anne Bradstreet’s “Elegie upon That Honorable and Renowned Knight, Sir Philip Sidney”
Authors: Sauer Elizabeth
Published: December 2021

The legacy of Sir Philip Sidney, the distinguished Elizabethan courtier-poet, was the subject of numerous claims to memorialization. On 17 October 1586 Sidney died in battle at Arnhem in the United Netherlands. Less than a week later, his corpse was transported to Flushing, of which Sidney had been Governor, and in the following year Sidney’s body was “interr’d in stately Pauls”, as recorded by Anne Dudley Bradstreet—the first known poet of the British North American colonies. While Bradstreet is omitted from most early modern and contemporary literary accounts of Sidney’s legacy, this article demonstrates that Bradstreet’s commemoration of Sidney from across the Atlantic presents new insights into his afterlife and the female poet’s formulations of early modern nationhood. Bradstreet’s first formal poem, “An Elegie upon that Honorable and renowned Knight, Sir Philip Sidney” (comp. 1637–8), was a tribute to Sidney as well as to her own Anglo-American literary heritage and England’s rolls. Bradstreet exhibits her complex relationship to Sidney along the same lines that she reconceives her English identity. A comparison of the two published seventeenth-century editions of Bradstreet’s elegiac poem (1650, 1678) shows how she translates descent and lineage from kinship (and kingship) into poetic creation. In the process, Bradstreet takes her place not only as a “semi-Sidney”, as Josuah Sylvester characterized Sidney’s descendants, but also as a Sidneian Muse—in America.
Insights into the Migration Routes and Historical Dispersion of Species Surviving the Messinian Crisis: The Case of Patella ulyssiponensis and Epizoic Rhodolith Lithophyllum hibernicum
Authors: Gomes Nuno , Antunes Carlos , Costa Dimítri de Araújo
Published: December 2021

The genus Patella (Patellogastropoda, Mollusca) is represented by a group of species exclusive to the Northeast Atlantic Ocean (including Macaronesian archipelagos) and Mediterranean Sea. The species Patella ulyssiponensis and Patella aspera are common in European waters, with the first inhabiting continental coast, and the second endemic to Macaronesian archipelagos. However, the acceptance of these two lineages as separate species is still highly debated. The red coralline species algae Lithophyllum hibernicum, distributed from Northeast Atlantic to the Mediterranean, is usually found as epilithic crusts or unattached forms (named rhodolith beds), although it also forms epizoic crusts on other organisms, e.g., shell surfaces. In order to study the historic dispersal and migration routes of the Patella ulyssiponensis-aspera complex, taxonomic, genetic and biogeographic approaches were employed based on haplotype network analyses and estimations for the most common recent ancestor (TMRCA), using Cytochrome Oxydase I. A synonymy for these two species is proposed, with the presence of a shared haplotype between the continental (P. ulyssiponensis) and insular (P. aspera) lineages, and with basis of morphological and nomenclatural data. We propose an evolutionary scenario for its dispersal based on a high haplotype diversity for the Mediterranean regions, indicating its possible survival during the Messinian Salinity Crisis (6–5.3 Mya), followed by a colonization of the Proto-Macaronesian archipelagos. The epizoic association of L. hibernicum on P. ulyssiponensis shell adult surface is recorded in this study, likewise the promotion of settlement conditions provided by these coralline algae to P. ulyssiponensis larvae, may explain the reach of P. ulyssiponensis distribution through rhodolith transportation.
Step In, Step Out from the First Lockdown: An Exploration of COVID-19 Perceptions in France and Quebec
Authors: David Jean-Charles , Nadarajah Kévin , Niang Anta , Delouvée Sylvain , Goyette Martin , Bordel Stéphanie , Somat Alain
Published: December 2021

Objective. The objective of this research was to describe and analyze the role of psychological and behavioral factors on perceptions of COVID-19 in France and Quebec at three different times during the pandemic. Design. We conducted three qualitative and quantitative studies (Study 1 N = 255, Study 2 N = 230, Study 3 N = 143). Participants were asked to evaluate psychological and behavioral measures: at the beginning of lockdown (Study 1), during lockdown (Study 2), and during lockdown exit (Study 3). Results. Results of Study 1 show that perceptions of COVID-19 are organized around fear and a sense of threat. During the lockdown, participants mentioned for the first time the health practices to prevent the spread of COVID-19 (Study 2). Psychological and social impacts constitute a central theme in participants’ discourse (Study 2 and 3). Conclusions. The results show that perceptions of risk during a pandemic are socially constructed. Perceptions seem to be influenced by the political and health management of a territory and by the evolution of behavioral and psychological responses.
Influence of Government Information on Farmers’ Participation in Rural Residential Environment Governance: Mediating Effect Analysis Based on Moderation
Authors: Wang Bowen , Hu Desheng , Hao Diandian , Li Meng , Wang Yanan
Published: December 2021

Rural revitalisation in China relies heavily on the rural residential environment and is vital to the well-being of farmers. The governance of rural human settlements is a kind of public good. The external economy of governance results in the free-riding behaviour of some farmers, which does not entice farmers to participate in governance. However, current research seldom considers the public good of rural human settlements governance. This research is based on the pure public goods attribute of rural human settlements governance. It begins with government information and, using structural equation modelling (SEM), researchers construct the influence mechanism of government information, attitude, attention, and participation ability on the depth of farmers’ participation. The empirical results show that ability, attention, and attitude all have a dramatic positive influence on the depth of farmers’ participation, and the degree of impact gradually becomes weaker. Additionally, government information stimulus is not enough to promote farmers’ deep participation in governance. It needs to rely on intermediary variables to indirectly affect the depth of participation (ability, attention, attitude), and there is a path preference for the influence of government information on the depth of participation. As an important organisation in the management of rural areas, the village committee can significantly adjust the effect of the degree of attention on the depth of participation of farmers. Therefore, the government not only needs to provide farmers with reliable and useful information, but also needs to combine necessary measures to guide farmers to participate in the governance of rural human settlements.
Examining the Relation between Caregiver Mental Health and Student Outcomes in Rural China
Authors: Wang Huan , Cousineau Claire , Hu Yuwei Adeline , Hu Grace , Qi Sunny , Sun Adrian , Wu Helen , Rozelle Scott , Singh Manpreet
Published: December 2021

Research continues to highlight the central relationship between caregivers’ mental health and their children’s development. This study examined the relation between primary caregivers’ mental health and school-aged children’s outcomes, including student mental health, resilience, and academic performance, in rural China. Using cross-sectional data from economically poor areas in the Gansu province, 2989 students (mean age = 11.51, 53.33% male, 46.67% female) and their primary caregivers (74.2% female) completed the 21-item, self-report Depression Anxiety Stress Scale. Students also completed the 25-item Connor-Davidson Resilience Scale and a standardized math test. The results indicated a high prevalence of caregiver depression (31%), stress (39%), and anxiety (24%). Characteristics that were significantly correlated with caregiver mental health issues included being a grandparent, having a low socioeconomic status and low education level, and living in a household with at least one migrant worker. Apart from caregiver stress and student resilience, caregiver mental health issues were negatively correlated with all student outcomes, including student mental health, resilience, and academic performance. Although additional empirical research is needed to investigate the associations between caregiver mental health and student outcomes, our results suggest that rural communities could benefit greatly from programs focused on improving the mental health of caregivers and this, in turn, may have a positive impact on student outcomes.
Epidemiology, Clinical Characteristics, and Risk Factors for Running-Related Injuries among South African Trail Runners
Authors: Viljoen Carel T. , Janse van Rensburg Dina C. , Verhagen Evert , van Mechelen Willem , Korkie Elzette , Botha Tanita
Published: December 2021

Trail running involves running on varying natural terrains, often including large elevation gains/losses. Trail running has a high risk of injury, and runners often participate in remote regions where medical support is challenging. The aim of this study was to determine the epidemiology, clinical characteristic, and associated injury risk factors among trail runners. A modified Oslo Sports Trauma Research Center Questionnaire for Health Problems (OSTRC-H) was used biweekly to collect running-related injury (RRI) and training history data prospectively, among 152 participants (males n = 120, females n = 32) over 30 weeks. We report an overall injury rate of 19.6 RRIs per 1000 h and an RRI mean prevalence of 12.3%. The leading anatomical site of RRIs was the lower limb (82.9%), affecting the knee (29.8%), shin/lower leg (18.0%), and the foot/toes (13.7%). A history of previous RRI in the past 12 months (p = 0.0032) and having a chronic disease (p = 0.0188) are independent risk factors for RRIs among trail runners. Two in three trail runners sustain an RRI mainly affecting the knee, shin/lower leg, and foot/toes. A history of previous RRI in the past 12 months and a having chronic disease is independently associated with RRI among trail runners. These results could be used to develop future RRI prevention strategies, combined with clinical knowledge and experience.
Use of Antibiotic Treatment in Pregnancy and the Risk of Several Neonatal Outcomes: A Population-Based Study
Authors: Cantarutti Anna , Rea Federico , Franchi Matteo , Beccalli Benedetta , Locatelli Anna , Corrao Giovanni
Published: December 2021

Background: Limited evidence is available on the safety and efficacy of antimicrobials during pregnancy, with even less according to the trimester of their use. Objective: This study aimed to evaluate the association between exposure to antibiotics therapy (AT) during pregnancy and short-term neonatal outcomes. Methods: We considered 773,237 deliveries that occurred between 2007–2017 in the Lombardy region of Italy. We evaluated the risk of neonatal outcomes among infants that were born to mothers who underwent AT during pregnancy. The odds ratios and the hazard ratios, with the 95% confidence intervals, were estimated respectively for early (first/second trimester) and late (third trimester) exposure. The propensity score was used to account for potential confounders. We also performed subgroup analysis for the class of AT. Results: We identified 132,024 and 76,921 singletons that were exposed to AT during early and late pregnancy, respectively. Infants born to mothers with early exposure had 17, 11, and 16% increased risk of preterm birth, low birth weight, and low Apgar score, respectively. Infants that were exposed in late pregnancy had 25, 11, and 13% increased risk of preterm birth, low birth weight, and low Apgar score, respectively. The results were consistent in the subgroup analysis. Conclusion: Our results suggested an increased risk of several neonatal outcomes in women exposed to ATs during pregnancy, albeit we were not able to assess to what extent the observed effects were due to the infection itself. To reduce the risk of neonatal outcomes, women that are prescribed AT during pregnancy should be closely monitored.
The Effect of Local and Global Interventions on Epidemic Spreading
Authors: Fan Jiarui , Du Haifeng , Wang Yang , He Xiaochen
Published: December 2021

Epidemic spreading causes severe challenges to the global public health system, and global and local interventions are considered an effective way to contain such spreading, including school closures (local), border control (global), etc. However, there is little study on comparing the efficiency of global and local interventions on epidemic spreading. Here, we develop a new model based on the Susceptible-Exposed-Infectious-Recovered (SEIR) model with an additional compartment called “quarantine status”. We simulate various kinds of outbreaks and interventions. Firstly, we predict, consistent with previous studies, interventions reduce epidemic spreading to 16% of its normal level. Moreover, we compare the effect of global and local interventions and find that local interventions are more effective than global ones. We then study the relationships between incubation period and interventions, finding that early implementation of rigorous intervention significantly reduced the scale of the epidemic. Strikingly, we suggest a Pareto optimal in the intervention when resources were limited. Finally, we show that combining global and local interventions is the most effective way to contain the pandemic spreading if initially infected individuals are concentrated in localized regions. Our work deepens our understandings of the role of interventions on the pandemic, and informs an actionable strategy to contain it.
Ethnic Differences in Environmental Restoration: Arab and Jewish Women in Israel
Authors: Saadi Diana , Schnell Izhak , Tirosh Emanuel
Published: December 2021

Throughout the last few decades, plenty of attention has been paid to restorative environments that positively affect human psychological health. These studies show that restorative environments affect human beings emotionally, physiologically, and cognitively. Some studies focus on the cognitive effects of exposure to restorative environments. A widely used index that measures the cognitive response is the Perceived Restoration Potential Scale (PRS). Most studies employing the PRS have examined differences in human cognitive response between types of urban environments mainly urban versus green ones. We use Hartig’s questionnaire to expose differences between types of urban environments and ethnic groups. Variances between Arab and Jewish women were calculated in four environments: home; park; residential and central city environments. The effect of intervening variables such as exposure to thermal, noise, social and CO loads and social discomfort were tested. We find that dissimilar to urban typical built-up environments, green areas are highly restorative. Furthermore, differences in the restorativeness of different urban environments are low though significant. These differences depend on their function, aesthetic qualities, and amount of greenery. Ethno-national differences appear to affect the experience of restoration. While both ethnic related groups experienced a tremendous sense of restoration in parks, Jewish women enjoyed slightly higher levels of restoration mainly at home and in residential environments compared to Arab women who experienced higher sense of restorativness in central city environments. Jewish women experienced higher sense of being away and fascination. From the intervening variables, social discomfort explained 68 percent of the experience of restoration, noise explained 49 percent, thermal load explained 43 percent and ethnicity 14 percent of the variance in PRS.
β-Glucans Could Be Adjuvants for SARS-CoV-2 Virus Vaccines (COVID-19)
Authors: Córdova-Martínez Alfredo , Caballero-García Alberto , Roche Enrique , Noriega David C.
Published: December 2021

Waiting for an effective treatment against the SARS-CoV-2 virus (the cause of COVID-19), the current alternatives include prevention and the use of vaccines. At the moment, vaccination is the most effective strategy in the fight against pandemic. Vaccines can be administered with different natural biological products (adjuvants) with immunomodulating properties. Adjuvants can be taken orally, complementing vaccine action. Adjuvant compounds could play a key role in alleviating the symptoms of the disease, as well as in enhancing vaccine action. Adjuvants also contribute to an effective immune response and can enhance the protective effect of vaccines in immunocompromised individuals such as the elderly. Adjuvants must not produce adverse effects, toxicity, or any other symptoms that could alter immune system function. Vaccine adjuvants are substances of wide varying chemical structure that are used to boost the immune response against a simultaneously administered antigen. Glucans could work as adjuvants due to their immunomodulatory biological activity. In this respect, β-(1,3)-(1,6) glucans are considered the most effective and safe according to the list issued by the European Commission. Only glucans with a β-(1,3) bond linked to a β-(1,6) are considered modulators of certain biological responses. The aim of this review is to present the possible effects of β-glucans as adjuvants in the efficacy of vaccines against SARS-CoV-2 virus.
Influence of the Psychomotor Profile in the Improvement of Learning in Early Childhood Education
Authors: Borrego-Balsalobre Francisco José , Martínez-Moreno Alfonso , Morales-Baños Vicente , Díaz-Suárez Arturo
Published: December 2021

The development of psychomotor skills in childhood enables children to organise the outside world through their bodies, contributing to their intellectual, affective, and social development. The present study aimed to longitudinally evaluate the psychomotor profile, throughout three academic years, of 3, 4 and 5-year-olds belonging to the second cycle of infant school, relating it descriptively to academic performance. The sample consisted of 82 subjects aged between 3 and 6 years throughout the study. The distribution of the sample was homogeneous, with 47.6% boys (n = 39) and 52.4% girls (n = 43). The results not only highlight the importance of the development and stimulation of motor skills from an early age for the overall development of the child, but also, when related to previous studies, show how they influence the development of human beings in adulthood.
Dyslipidemia, Obesity, and Ethnicity in Mexican Children
Authors: Costa-Urrutia Paula , Colistro Valentina , Franco-Trecu Valentina , Granados Julio , Álvarez Fariña Rafael , Rodríguez-Arellano Martha Eunice
Published: December 2021

The aim of this study was to assess lipid disorders in children from five ethnic groups, both urban and indigenous, from northern and central Mexico. We measured the lipid profile to determine the ability of the body mass index (BMI) to discriminate an abnormally high lipid level using receiving operating characteristics (ROC). We analyzed the association and interaction of obesity and ethnicity with lipid disorders using generalized linear models in 977 children. The highest prevalence of lipid disorders (high TG, high TC, high LDL, high APOB, and dyslipidemia) was found in central Mexico-Mexico City and urban northern Mexico. The BMI performed better at predicting low HDL in Seris, a northern indigenous group (0.95, CI: 0.69–0.85), and Mexico City (0.75, CI: 0.69–0.82), and high LDL in Puebla (central Mexico, 0.80, CI: 0.69–0.85). Obesity significantly (p < 0.05) increases lipid disorders by around two times (OR~2) for almost all lipid markers. Obesity and ethnic interaction increase the lipid disorders by more than five times for different lipid markers and ethnic groups (high total cholesterol OR = 5.31; low HDL OR = 5.11, and dyslipidemia OR = 5.68). Lipid disorders are not restricted to children with high BMIs, but obesity exacerbates these. The emerging lipid disorder risk depends on the ethnic group.
Semantic Network Analysis Using Construction Accident Cases to Understand Workers’ Unsafe Acts
Authors: Kang Suhyun , Cho Sunyoung , Yun Sungmin , Kim Sangyong
Published: December 2021

Unsafe acts by workers are a direct cause of accidents in the labor-intensive construction industry. Previous studies have reviewed past accidents and analyzed their causes to understand the nature of the human error involved. However, these studies focused their investigations on only a small number of construction accidents, even though a large number of them have been collected from various countries. Consequently, this study developed a semantic network analysis (SNA) model that uses approximately 60,000 construction accident cases to understand the nature of the human error that affects safety in the construction industry. A modified human factor analysis and classification system (HFACS) framework was used to classify major human error factors—that is, the causes of the accidents in each of the accident summaries in the accident case data—and an SNA analysis was conducted on all of the classified data to analyze correlations between the major factors that lead to unsafe acts. The results show that an overwhelming number of accidents occurred due to unintended acts such as perceptual errors (PERs) and skill-based errors (SBEs). Moreover, this study visualized the relationships between factors that affected unsafe acts based on actual construction accident case data, allowing for an intuitive understanding of the major keywords for each of the factors that lead to accidents.
Recreational Screen Time Use among a Small Sample of Canadians during the First Six Months of the COVID-19 Pandemic
Authors: Coyne Paige , Staffell Zach , Woodruff Sarah J.
Published: December 2021

(1) Background: The coronavirus (COVID-19) pandemic has caused disruptions in the daily lives of individuals in Canada. Purpose: Examine how total and specific (i.e., watching television, using social media, going on the Internet, playing video games, and engaging in virtual social connection) recreational screen time behaviours changed throughout the first six months of the COVID-19 pandemic, in comparison to pre-pandemic levels; (2) Methods: Sixty four Canadians (mostly Caucasian, female, age range = 21–77 years) completed monthly surveys from April to September of 2020; (3) Results: A one-way repeated measures analysis of variance (RM-ANOVA) and subsequent post hoc analysis revealed that total recreational screen time was statistically higher in late March/April (292.5 min/day ± 143.0) and into May, compared to pre-COVID-19 (187.8 min/day ± 118.3), before declining in subsequent months; (4) Conclusions: Generally, specific recreational screen time behaviours, such as time spent watching television, followed the same trend. Future studies with larger sample sizes and from other countries examining recreational screen time behaviours longitudinally over the pandemic are still needed to allow for greater generalizability.
A Systematic Review of Child Health and Developmental Outcomes Associated with Low Birthweight and/or Small for Gestational Age in Indigenous Children from Australia, Canada and New Zealand
Authors: Batchelor Madeleine , Brown Stephanie J. , Glover Karen , Gartland Deirdre
Published: December 2021

While much is known about the health implications of low birthweight for infants and adults, there is limited information about the health implications in childhood, particularly for Indigenous children. The aim of this systematic review was to assess associations between low birthweight (LBW) and/or small for gestational age (SGA) and the developmental, physical or mental health outcomes for Australian, Canadian and New Zealand Indigenous children (5–12 years), including the potential mediating role of cultural connections. The review was guided by an Aboriginal Advisory Group established to guide the Aboriginal Families Study. Four databases were investigated with pre-determined inclusion/exclusion criteria. The search identified 417 articles after independent screening by two authors. Eight studies assessing six child outcomes were included. The review identified limited evidence, although the review suggested possible links between LBW and/or SGA and childhood asthma, lower body mass index (BMI) and poorer academic performance. Links between LBW, SGA and disability, global health and developmental vulnerability were inconclusive. One study identified cultural-based resilience as protective against perinatal adversity. In summary, research on the relationship between adverse birth outcomes and Indigenous children’s health and development is limited. Further investigation and collaboration with Indigenous communities is required to drive optimised health and social services responses and equitable system reform.
Impacts of Visualizations on Decoy Effects
Authors: Jeong Yuin , Oh Sangheon , Kang Younah , Kim Sung-Hee
Published: December 2021

The decoy effect is a well-known, intriguing decision-making bias that is often exploited by marketing practitioners to steer consumers towards a desired purchase outcome. It demonstrates that an inclusion of an alternative in the choice set can alter one’s preference among the other choices. Although this decoy effect has been universally observed in the real world and also studied by many economists and psychologists, little is known about how to mitigate the decoy effect and help consumers make informed decisions. In this study, we conducted two experiments: a quantitative experiment with crowdsourcing and a qualitative interview study—first, the crowdsourcing experiment to see if visual interfaces can help alleviate this cognitive bias. Four types of visualizations, one-sided bar chart, two-sided bar charts, scatterplots, and parallel-coordinate plots, were evaluated with four different types of scenarios. The results demonstrated that the two types of bar charts were effective in decreasing the decoy effect. Second, we conducted a semi-structured interview to gain a deeper understanding of the decision-making strategies while making a choice. We believe that the results have an implication on showing how visualizations can have an impact on the decision-making process in our everyday life.
CRISPR Screen Contributes to Novel Target Discovery in Prostate Cancer
Authors: Tsujino Takuya , Komura Kazumasa , Inamoto Teruo , Azuma Haruhito
Published: December 2021

Prostate cancer (PCa) is one of the common malignancies in male adults. Recent advances in omics technology, especially in next-generation sequencing, have increased the opportunity to identify genes that correlate with cancer diseases, including PCa. In addition, a genetic screen based on CRISPR/Cas9 technology has elucidated the mechanisms of cancer progression and drug resistance, which in turn has enabled the discovery of new targets as potential genes for new therapeutic targets. In the era of precision medicine, such knowledge is crucial for clinicians in their decision-making regarding patient treatment. In this review, we focus on how CRISPR screen for PCa performed to date has contributed to the identification of biologically critical and clinically relevant target genes.
Predictive Maintenance for Switch Machine Based on Digital Twins
Authors: Yang Jia , Sun Yongkui , Cao Yuan , Hu Xiaoxi
Published: December 2021

As a unique device of railway networks, the normal operation of switch machines involves railway safe and efficient operation. Predictive maintenance becomes the focus of the switch machine. Aiming at the low accuracy of the prediction state and the difficulty in state visualization, the paper proposes a predictive maintenance model for switch machines based on Digital Twins (DT). It constructs a DT model for the switch machine, which contains a behavior model and a rule model. The behavior model is a high-fidelity visual model. The rule model is a high-precision prediction model, which is combined with long short-term memory (LSTM) and autoregressive Integrated Moving Average model (ARIMA). Experiment results show that the model can be more intuitive with higher prediction accuracy and better applicability. The proposed DT approach is potentially practical, providing a promising idea for switching machines in predictive maintenance.
Multimatcher Model to Enhance Ontology Matching Using Background Knowledge
Authors: Al-Yadumi Sohaib , Goh Wei-Wei , Tan Ee-Xion , Jhanjhi Noor Zaman , Boursier Patrice
Published: December 2021

Ontology matching is a rapidly emerging topic crucial for semantic web effort, data integration, and interoperability. Semantic heterogeneity is one of the most challenging aspects of ontology matching. Consequently, background knowledge (BK) resources are utilized to bridge the semantic gap between the ontologies. Generic BK approaches use a single matcher to discover correspondences between entities from different ontologies. However, the Ontology Alignment Evaluation Initiative (OAEI) results show that not all matchers identify the same correct mappings. Moreover, none of the matchers can obtain good results across all matching tasks. This study proposes a novel BK multimatcher approach for improving ontology matching by effectively generating and combining mappings from biomedical ontologies. Aggregation strategies to create more effective mappings are discussed. Then, a matcher path confidence measure that helps select the most promising paths using the final mapping selection algorithm is proposed. The proposed model performance is tested using the Anatomy and Large Biomed tracks offered by the OAEI 2020. Results show that higher recall levels have been obtained. Moreover, the F-measure values achieved with our model are comparable with those obtained by the state of the art matchers.
Private Car O-D Flow Estimation Based on Automated Vehicle Monitoring Data: Theoretical Issues and Empirical Evidence
Authors: Comi Antonio , Rossolov Alexander , Polimeni Antonio , Nuzzolo Agostino
Published: December 2021

Data on the daily activity of private cars form the basis of many studies in the field of transportation engineering. In the past, in order to obtain such data, a large number of collection techniques based on travel diaries and driver interviews were used. Telematics applied to vehicles and to a broad range of economic activities has opened up new opportunities for transportation engineers, allowing a significant increase in the volume and detail level of data collected. One of the options for obtaining information on the daily activity of private cars now consists of processing data from automated vehicle monitoring (AVM). Therefore, in this context, and in order to explore the opportunity offered by telematics, this paper presents a methodology for obtaining origin–destination flows through basic info extracted from AVM/floating car data (FCD). Then, the benefits of such a procedure are evaluated through its implementation in a real test case, i.e., the Veneto region in northern Italy where full-day AVM/FCD data were available with about 30,000 vehicles surveyed and more than 388,000 trips identified. Then, the goodness of the proposed methodology for O-D flow estimation is validated through assignment to the road network and comparison with traffic count data. Taking into account aspects of vehicle-sampling observations, this paper also points out issues related to sample representativeness, both in terms of daily activities and spatial coverage. A preliminary descriptive analysis of the O-D flows was carried out, and the analysis of the revealed trip patterns is presented.
The Systems and Methods of Game Design
Authors: Pinto Neves Pedro , Zagalo Nelson
Published: December 2021

Even a cursory glance at scholarly literature from over a decade ago related to games can show authors variously prefacing their contributions with explanations of the newness of games, the impressive growth of the digital games industry, and the interdisciplinary nature of games [...]
Optimization of the Mashaer Shuttle-Bus Service in Hajj: Arafat-Muzdalifah Case Study
Authors: Hussain Omar , Felemban Emad , Rehman Faizan Ur
Published: December 2021

Hajj, the fifth pillar of Islam, is held annually in the month of Dhul Al-Hijjah, the twelfth month, in the Islamic calendar. Pilgrims travel to Makkah and its neighbouring areas—Mina, Muzdalifah, and Arafat. Annually, about 2.5 million pilgrims perform spatiotemporally restricted rituals in these holy places that they must execute to fulfil the pilgrimage. These restrictions make the task of transportation in Hajj a big challenge. The shuttle bus service is an essential form of transport during Hajj due to its easy availability at all stages and ability to transport large numbers. The current shuttle service suffers from operational problems; this can be deduced from the service delays and customer dissatisfaction with the service. This study provides a system to help in planning the operation of the service for one of the Hajj Establishments to improve performance by determining the optimal number of buses and cycles required for each office in the Establishment. We will also present a case study in which the proposed model was applied to the non-Arab Africa Establishment shuttle service. At the same time, we will include the mechanism for extracting the information required in the tested model from the considerably large GPS data of 20,000+ buses in Hajj 2018.
Screening of Honey Bee Pathogens in the Czech Republic and Their Prevalence in Various Habitats
Authors: Mráz Petr , Hýbl Marian , Kopecký Marek , Bohatá Andrea , Hoštičková Irena , Šipoš Jan , Vočadlová Kateřina , Čurn Vladislav
Published: December 2021

Western honey bee (Apis mellifera) is one of the most important pollinators in the world. Thus, a recent honey bee health decline and frequent honey bee mass losses have drawn attention and concern. Honey bee fitness is primarily reduced by pathogens, parasites, and viral load, exposure to pesticides and their residues, and inadequate nutrition from both the quality and amount of food resources. This study evaluated the prevalence of the most common honey bee pathogens and viruses in different habitats across the Czech Republic. The agroecosystems, urban ecosystems, and national park were chosen for sampling from 250 colonies in 50 apiaries. Surprisingly, the most prevalent honey bee pathogens belong to the family Trypanosomatidae including Lotmaria passim and Crithidia mellificae. As expected, the most prevalent viruses were DWV, followed by ABPV. Additionally, the occurrence of DWV-B and DWV-C were correlated with honey bee colony mortality. From the habitat point of view, most pathogens occurred in the town habitat, less in the agroecosystem and least in the national park. The opposite trend was observed in the occurrence of viruses. However, the prevalence of viruses was not affected by habitat.
A New Genus and Species of Lophocateridae from Mid-Cretaceous Amber of Myanmar (Coleoptera)
Authors: Yu Ya-Li , Li Yan-Da , Kolibáč Jiří , Ślipiński Adam , Ren Dong , Pang Hong , Li Zhi-Qiang
Published: December 2021

A new genus and species of the cleroid family Lophocateridae are described and illustrated from the mid-Cretaceous amber of northern Myanmar. Gracilenticrus burmiticus Yu, Kolibáč & Ślipiński gen. et sp. nov. is unique among Lophocateridae in the tiny body size, frontoclypeal suture and antennal grooves absent, symmetrical antennal clubs, protrochantin reduced, tarsal claws small and widened at base. A key to the species of Mesozoic Lophocateridae is also provided. Morphological characters of the newly discovered Gracilenticrus were analyzed together with representatives of 43 extant genera of Cleroidea (broadly defined Trogossitidae) in a matrix of 91 characters. Gracilenticrus burmiticus was resolved as a member of Lophocateridae. The discovery of a diverse fauna of Lophocateridae in the mid-Cretaceous sheds a new light on the early evolution of superfamily Cleroidea.
The Influence of Temperature and Host Gender on Bacterial Communities in the Asian Citrus Psyllid
Authors: Jiang Rui-Xu , Shang Feng , Jiang Hong-Bo , Dou Wei , Cernava Tomislav , Wang Jin-Jun
Published: December 2021

The Asian citrus psyllid, D. citri Kuwayama is the primary vector for Candidatus Liberibacter asiaticus (CLas), which causes a destructive disease in citrus plants. Bacterial symbionts are important determinants of insect physiology, and they can be impacted by many external factors. Temperature is an important abiotic factor affecting insect physiology, and it is also known that differences in symbiont proportions may vary in different insect genders. To date, it is unclear how the symbionts of D. citri are affected by temperature and gender. This study used high-throughput sequencing of 16S ribosomal RNA amplicons to determine how temperature and gender affect the bacterial communities present in D. citri. We identified 27 amplicon sequence variants (ASVs) belonging to 10 orders, seven classes, and five phyla. The dominant phylum was Proteobacteria (99.93%). Other phyla, including Firmicutes, Bacteroidota, Deinococcota, Cyanobacteria, and Actinobacteriota, were less abundant (<0.1%). Profftella (71.77–81.59%) and Wolbachia (18.39–28.22%) were the predominant taxa in all samples. Under high-temperature treatment, Profftella was more common in females, while Wolbachia had a higher abundance in males. In males, Profftella was more abundant under low-temperature treatments than under high-temperature treatments. In contrast, Wolbachia showed a higher abundance under high-temperature treatments than under low-temperature treatments. An RT-qPCR (quantitative real-time PCR) approach confirmed the results obtained with high-throughput DNA sequencing. Our results provide a basis for understanding the co-adaptation of D. citri and its symbionts to environmental temperature stress.
Isolation and Characterization of Mosquito-Associated Spiroplasma cantharicola from Aedes japonicus Collected in Hokkaido, Japan
Authors: Shimooka Makoto , Sakurai Yoshimi , Muramatsu Yasukazu , Uchida Leo
Published: December 2021

Species of the genus Spiroplasma are common within arthropods and plants worldwide. Mosquito-associated Spiroplasma spp. have been reported to show pathogenicity toward mosquitoes, which serve as vectors of several infectious diseases that have detrimental effects on public health. Although Spiroplasma spp. are expected to have potential use as biological vector-control tools, characteristics such as their distribution, host species, and cytopathogenic effects (CPEs) are not well understood. In this study, we isolated a Spiroplasma sp. from a female Aedes japonicus collected in Hokkaido, northern Japan. Phylogenetic analysis based on the 16S rRNA gene sequence indicated our isolate was closely related to S. cantharicola. We screened 103 mosquito pools consisting of 3 genera and 9 species, but only detected S. cantharicola in the first isolation. In an in vitro assay, our isolate grew well at 28 °C, but no propagation was observed at 37 °C. Furthermore, the isolate showed strong CPE on a mosquito-derived cultured cell line (C6/36), and its propagation slightly increased when co-cultured with C6/36 cells. To our knowledge, this is the third report of the isolation of S. cantharicola from mosquitoes and the first case in Asia. Our findings provide epidemiological data on S. cantharicola distribution in the region.
Predatory Ability of Harmonia axyridis (Coleoptera: Coccinellidae) and Orius sauteri (Hemiptera: Anthocoridae) for Suppression of Fall Armyworm Spodoptera frugiperda (Lepidoptera: Noctuidae)
Authors: Di Ning , Zhang Kai , Xu Qingxuan , Zhang Fan , Harwood James D. , Wang Su , Desneux Nicolas
Published: December 2021

The lepidopteran pest, Spodoptera frugiperda (JE Smith), spread rapidly after its first detection in China and has caused significant yield loss to maize production in the southwestern part of the country. Although natural enemies of S. frugiperda are present in the field, biological control using naturally distributed predators is ineffective because their underlying populations are too low. To enhance our understanding of the potential role of natural enemies in regulating this invasive pest, functional response experiments were conducted to quantify the response of two predators, Orius sauteri (Poppius) (Hemiptera: Anthocoridae) and Harmonia axyridis (Pallas) (Coleoptera: Coccinellidae), in terms of consumption of S. frugiperda. Experimental results revealed that the predatory effects of nymphs of O. sauteri and H. axyridis on the eggs and larvae of S. frugiperda fitted Holling’s Type II functional response model. Importantly, the theoretical maximum number of prey consumed per day (Na-max), the instantaneous attack rate (a′) and the handling time (Th) of O. sauteri nymphs on S. frugiperda eggs were 15.19, 0.7444 and 0.049 d, respectively; and the parameters on first instar larvae of S. frugiperda were 700.24, 0.5602 and 0.0008 d, respectively. These data contrast to those of H. axyridis, where the Na-max, a′ and Th of adults on eggs of S. frugiperda were 130.73, 1.1112 and 0.085 d, respectively, and on the first instar larvae of S. frugiperda were 1401.1, 0.8407 and 0.0006 d, respectively. These results revealed that H. axyridis is a highly voracious predator of the eggs and young larvae of S. frugiperda and O. sauteri could also be used as biocontrol agent of this pest. Our work provides a theoretical framework for the application of natural enemies to control S. frugiperda in the field. Further research is required to strategize conservation biological control approaches in the field to increase populations of these predators and enhance the suppression of S. frugiperda.
Sensory Organ Investment Varies with Body Size and Sex in the Butterfly Pieris napi
Authors: Moradinour Zahra , Wiklund Christer , Jie Vun Wen , Restrepo Carlos E. , Gotthard Karl , Miettinen Arttu , Perl Craig D. , Baird Emily
Published: December 2021

In solitary insect pollinators such as butterflies, sensory systems must be adapted for multiple tasks, including nectar foraging, mate-finding, and locating host-plants. As a result, the energetic investments between sensory organs can vary at the intraspecific level and even among sexes. To date, little is known about how these investments are distributed between sensory systems and how it varies among individuals of different sex. We performed a comprehensive allometric study on males and females of the butterfly Pieris napi where we measured the sizes and other parameters of sensory traits including eyes, antennae, proboscis, and wings. Our findings show that among all the sensory traits measured, only antenna and wing size have an allometric relationship with body size and that the energetic investment in different sensory systems varies between males and females. Moreover, males had absolutely larger antennae and eyes, indicating that they invest more energy in these organs than females of the same body size. Overall, the findings of this study reveal that the size of sensory traits in P. napi are not necessarily related to body size and raises questions about other factors that drive sensory trait investment in this species and in other insect pollinators in general.
Impact of Biochar on Douglas-Fir Tussock Moth (Orgyia pseudotsugata Lepidoptera: Erebidae) Larvae Reared on Synthetic Diet
Authors: Rice-Marshall Stacey , Cook Stephen P. , Randall John
Published: December 2021

The use of biochar as a soil amendment in forest ecosystems can be beneficial in the restoration of degraded soils. Forest insects such as the Douglas-fir tussock moth, Orgyia pseudotsugata (McDonnough) (Lepidoptera: Erebidae), may be exposed to biochar when the material is applied. Two experiments were conducted using biochar either (1) applied to the surface of the diet at three rates (0, 5, and 10 mg) or (2) incorporated into synthetic diet at four rates (0, 10, 20, and 40% volume/volume). The objective of both experiments was to determine if biochar on the surface or incorporated into a synthetic diet affected development and survival of O. pseudotsugata larvae. In both experiments, there was a significant decrease in estimated time to larval mortality in all biochar treatments compared to untreated controls. In the surface-applied biochar experiment, there was a significant difference in larval weight gain at day 12 between the control and 10 mg biochar treatments. In the experiment with biochar incorporated into the diet, mean larval weight at day 12 was highest in the low (10%) biochar treatment compared to all other treatments, although weight gain was only significantly different between the low- and high-concentration (40%) biochar treatments. Our results suggest that larvae, feeding on a low amount of biochar in the synthetic diet, may respond by engaging in compensatory feeding behavior. Fewer surviving larvae in the biochar treatment groups may contribute to the lack of significance found in the comparison of weight gain at day 24 in each experiment.