bluuebunny/crossref_metadata_2025 huggingface dataset:
Male-built nest volume varies with colony and the timing of the breeding season but not with the nesting-substrate quality and egg production in whiskered terns
Authors: PAILLISSON JEAN MARC , Chambon Rémi
Published: April 2021

Nest building can represent an energetically-costly activity for a
variety of animal taxa. Besides, the determinants of within-species
variation in the design of nests, notably with respect to natural and
sexual selection, are still poorly known although the situation has been
partly remedied recently. Based on an observational study, we examined
the influence of nesting conditions (nesting-substrate quality, colony,
laying date, and year) on the volume of male-built nests and its
potential role as a post-mating sexually-selected display in the
whiskered tern Chlidonias hybrida, a monogamous species with obligate
bi-parental care breeding on unstable aquatic vegetation beds. No
relationship was found between the nest volume and the nesting-substrate
quality (i.e. nest stability) indicating that the density of white
waterlily leaves was large enough when whiskered terns breed. In
contrast, building a large nest likely constitutes a selective advantage
since nests were larger in less densely populated colonies and for early
breeders whatever the year. Since being influenced by nesting
conditions, the volume of male-built nests was unlikely to be a sexually
selected trait in whiskered terns. The reproductive effort by females
(the probability of laying one, two or three eggs, and variation in mean
egg volume per clutch) was indeed not correlated with the volume of
male-built nests. The fitness consequences of building a large nest are
yet to be studied and additional investigations are recommended to
better depict the participation of males early during breeding
(including notably courtship feeding) and later to chick provisioning.
Hypothermic Circulatory Arrest Time affects neurological outcomes of Frozen Elephant Trunk for Acute Type A Aortic Dissection: a systematic review and meta-analysis
Authors: Mousavizadeh Mostafa , Daliri Mahdi , Aljadayel Hadi Abo , Idhrees Mohammed , Rezaei Yousef , Bashir Mohamad , Hosseini Saeid
Published: April 2021

Background: The treatment of complex thoracic aorta pathologies remains
a challenge for cardiovascular surgeons. After introducing Frozen
Elephant Trunk (FET), a significant evolution of surgical techniques has
been achieved. The present meta-analysis aimed to assess the efficacy of
FET in acute type A aortic dissection (ATAAD) and the effect of
circulatory arrest time on post-operative neurologic outcomes. Methods:
A standard Preferred Reporting Items for Systematic Reviews and
Meta-Analyses search was conducted for all observational studies of
patients diagnosed with ATAAD undergoing total arch replacement with FET
reporting in-hospital mortality, bleeding, and neurological outcomes. A
random-effect meta-analysis was performed using STATA software
(StataCorp, TX, USA). Results: Thirty-five studies were eligible for the
present meta-analysis, including 3211 patients with ATAAD who underwent
total arch replacement with FET. The pooled estimate for in-hospital
mortality, postoperative stroke, and spinal cord injury were 7% (95%
CI 5 – 9; I2 = 68.65%), 5% (95% CI 4 – 7; I2 = 63.93%), and 3%
(95% CI 2 – 4; I2 = 19.56%), respectively. Univariate meta-regression
revealed that with increasing the duration of hypothermic circulatory
arrest time, the effect sizes for postoperative stroke and SCI enhances.
Conclusions: It seems that employing the FET procedure for acute type A
dissection is associated with acceptable neurologic outcomes and a
similar mortality rate comparing with other aorta pathologies. Besides,
increasing hypothermic circulation arrest time appears to be a
significant predictor of adverse neurologic outcomes after FET.
Volumetric De-Escalation and Improved Acute Toxicity with Proton Craniospinal Irradiation Using a Vertebral Body Sparing Technique
Authors: Chou Brian , Hopper Austin , Elster Jennifer , Crawford John , McConnell Kristen , Chang Andrew , Mundt Arno , MacEwan Iain
Published: April 2021

Purpose: Craniospinal irradiation (CSI) has historically treated the
entire vertebral body (VB) in growing children. Vertebral body sparing
proton craniospinal irradiation (VBSpCSI) is a technique which spares
the majority of the VB from significant irradiation. This retrospective
study reviews the acute toxicity of VBSpCSI compared to photon CSI.
Methods: Pediatric CSI patients treated between 2008 and 2018 were
evaluated. Patients were stratified to the VBSpCSI cohort or the photon
cohort and analyzed for acute toxicity profile during treatment and
disease-free survival (DFS). Statistical analysis was performed using
Kaplan-Meier log rank analysis for DFS and Fisher’s exact test for
toxicity. Results: Twenty-five patients received VBSpCSI and 13 patients
received photon CSI. Mean patient age at treatment was 7.5y (range 2 to
16). The cohorts were well-matched with respect to gender, age, and CSI
dose. Two-year DFS was similar between cohorts (81% VBSpCSI vs 61%
photon, p=0.18). Patients receiving VBSpCSI had lower rates of grade 2+
GI toxicity (24% vs 76.5%, p=0.005), grade 2+ nausea (24% vs 61.5%,
p=0.035), and any-grade esophagitis (0% vs 38%, p=0.0026). Patients
treated with VBSpCSI had lower red blood cell transfusion rates (21.7%
vs 60%, p=0.049) and grade 4+ lymphopenia (33.3% vs 77.8%, p=0.046).
Conclusions: VBSpCSI in children is a volumetric de-escalation from
traditional volumes which irradiate the entire vertebral body. Based on
our results, VBSpCSI was associated with less acute gastrointestinal and
hematologic toxicity. The study adds to the growing body of evidence
supporting the use of protons over photons for pediatric CSI.
Promoción de las competencias ligadas al pensamiento computacional a través del aprendizaje basado en el desarrollo de proyectos
Authors: Sánchez Márquez Juan Antonio , Móndelo Villaseñor Mónica , Mena Avilés Elizabeth , Méndez Martínez Ana Jovita
Published: April 2021

Problemática: la mayor complejidad de los problemas actuales demanda que los estudiantes fortalezcan sus competencias ligadas a la solución de problemas. Si enseñamos a los estudiantes a resolver problemas, ellos adquirirán independencia y confianza para enfrentar retos futuros. Objetivos: este proyecto se enfoca en la promoción de las competencias del pensamiento computacional a través del desarrollo de proyectos. Materiales y métodos: los alumnos trabajaron en el desarrollo de proyectos en equipo, haciendo uso de roles. Durante el desarrollo de los proyectos, los alumnos debieron procesar información, modelar los prototipos iniciales, evaluar las fallas e incorporar las ideas originales basadas en sus propios procesos creativos. Resultados: los resultados muestran que el principal reto que identificaron los alumnos fue el de generar acuerdos al interior de los grupos que les permitieran hacer adecuaciones a los prototipos y llegar a las versiones finales de estos. Discusión: en este proyecto, los alumnos fueron expuestos a situaciones que emularon ambientes reales de trabajo, en donde ellos debían desarrollar consensos al tiempo que identificaban una ruta sistemática para resolver problemas. Conclusiones: este tipo de proyectos genera un espacio idóneo para que los alumnos asuman roles, se comuniquen eficientemente, aprendan entre ellos y desarrollen soluciones innovadoras bajo un ambiente real de aprendizaje colaborativo. Contribución/originalidad: este proyecto permitirá que los docentes cuenten con una metodología de solución de problemas que podrán compartir con sus estudiantes a fin de que estos puedan aplicarla a la solución de problemas emulando situaciones que los alumnos encontrarán durante su desarrollo profesional y personal.
Alpha to Beta Cell Conversion in the Postpartum Mouse Pancreas involves Lgr5 Progeny
Authors: Rodriguez Uylissa A. , Socorro Mairobys , Criscimanna Angela , Martins Christina P. , Mohamed Nada , Hu Jing , Prasadan Krishna , Gittes George K. , Esni Farzad
Published: April 2021

In contrast to the skin
and the gut, where somatic stem cells and their niche are well characterized, a
definitive pancreatic multipotent cell population in the adult pancreas has yet
to be revealed. Of particular interest is whether such cells may be endogenous
in diabetic patients, and if so, can they be used for therapeutic purposes. In
the current study, we used two separate reporter lines to target Cre-recombinase
expression to the Lgr5 or glucagon expressing cells in the pancreas. We provide
evidence for the existence of a population of cells within and in the proximity
of the ducts that transiently express the stem cell marker Lgr5 during late
gestational stages. Careful timing of tamoxifen treatment in Lgr5EGFP-IRES-CreERT2;R26Tomato
mice allowed us to show that these Lgr5-expressing progenitor cells can
differentiate into α-cells during pregnancy. Furthermore, we report on a spontaneous
α-to β-cell lineage conversion specifically after parturition. The contribution
of Lgr5-progeny to the β-cell compartment through an α-cell intermediate phase early
on after pregnancy appears to be part of a novel mechanism that would counterbalance
against excessive β-cell mass reduction during β-cell involution.
Amalgamasi Dan Restrukturisasi Hindu-Buddha Dalam Kekawin Sutasoma
Authors: Dharmana I Wayan Suarsana
Published: April 2021

Kekawin Sutasoma menceritakan perjalanan Sang Sutasoma yang digubah oleh Rakawi Mpu Tantular pada masa pemerintahan Raja Hayam Wuruk dari Kerajaan Majapahit. Artikel ini mengkaji tentang struktur teks kekawin Sutasoma, sinopsis kekawin Sutasoma, amalgamasi dan restrukturisai Hindu (Siwa) Buddha pada kekawin Sutasoma.  Nilai terpenting yang terdapat dalam Sutasoma adalah ajaran untuk mencari intisari dari sebuah ajaran agama, dan menganggap agama Siwa dan Buddha yang kurun waktu itu berkembang di Majapahit memiliki intisari yang sama, sehingga dapat dijadikan acuan dalam memandang sebuah perbedaan agama hanya pada kulitnya saja, sedangkan intinya sama (persamaan dalam perbedaan). Sehingga pada masa Majapahit toleransi antarumat beragama terjaga dengan baik dan berpuncak pada masa keemasan Majapahit. Sutasoma melahirkan sesanti Bhinneka Tunggal Ika, sebuah mahakarya filosofi adiluhung dari Jawa Kuno yang masih sangat relevan dijadikan acuan dalam kehidupan beragama, berbangsa, dan bernegara.
Mengkontekstualisasi Kajian Pascakolonial dalam Bali Kontemporer
Authors: Suryawan I Ngurah
Published: April 2021

Artikel ini mengkaji tentang usaha untuk mengontekstualisasikan teori-teori pasca kolonial ke dalam fenomena Bali kontemporer. Meskipun Bali tidak lagi berada di dalam era penjajahan, namun warisan kebudayaan mental masih dapat disaksikan di dalam praktik kebudayaan, yang kemudian dikomodifikasi untuk kepentingan industri pariwisata. Pada titik ini, kajian pasca kolonial yang dirintis oleh Gayatri Spivak, Edward Said hingga Homi Babha bisa dipakai sebagai pisau bedah untuk melihat sejauh mana jejak superioritas penjajah terhadap inferioritas terjajah pada konteks Bali kontemporer. Di dalam struktur masyarakat Bali kontemporer yang terbentuk aibat persinggungan dengan globalisasi yakni kelas menegah, turut  mengadopsi perspektif eksotis kolonialistik untuk meromantisir kebudayaan Bali demi kepentingan ekonomi-politik neo-liberal yang difasilitasi oleh pariwisata budaya.
A RELAÇÃO ENTRE O PRINCÍPIO EDUCATIVO DE GRAMSCI COM A EDUCAÇÃO PROFISSIONAL NO ENSINO MÉDIO INTEGRADO AO PROEJA
Authors: Santos Stering Silvia Maria dos , Pinto de Carvalho Marilene Luzia , Assis Ricardo de , Domingas Pinto Marilda
Published: April 2021

A Educação Profissional e Tecnológica- EPT, na visão de Gramsci, no contexto da formação escolar na modernidade, se configura como expressão distorcida e limitada quanto às funções e formas da instrução profissional, da relação entre a separação desinteressada formativa e a profissional. Contudo, na busca pela superação das desigualdades sociais impostas pelo mundo do capital, a EPT surge como uma possibilidade para conciliar o rigor próprio da fábrica e o exercício reflexivo da exigência humanística, como possibilidade de realização da formação do trabalhador, para realizar uma educação vinculada aos objetivos estratégicos de um projeto similar à proposição de Gramsci, no que se refere à Escola Unitária, que busque não apenas a inclusão no contexto de uma sociedade desigual, mas a construção de uma nova sociedade, fundada na igualdade política, econômica e social. O artigo tem por objetivo evidenciar a relação entre o princípio educativo de Gramsci com a Educação Profissional no Ensino Médio Integrado ao Proeja. Trata-se de uma pesquisa bibliográfica documental. A investigação aponta que a sociedade atual, carece de uma escola que prepare sim para o mundo do trabalho, porém em uma perspectiva focada na democracia e na justiça social, capaz de compreender o trabalho como princípio educativo.
A szénhidrogének primer migrációja
Authors: Koncz István
Published: April 2021

A kisebb és nagyobb mélységben végbemenő primer migrációról közöl a szerző egy összefoglalást. A szénhidrogéneknek anyakőzeteikből történő kiszorulása minden szempontból (mennyiségileg és minőségileg egyaránt) nagyon jó anya kőzeteket igényel alacsony termikus érettség esetén, amikor a pelitek áteresztőképessége még mindig elég ahhoz, hogy a víz egy részének eltávozásával a hidrosztatikus nyomás fenn tudjon maradni. Nagyobb mélységben a pelitek túlnyomásossá válnak igen alacsony áteresztőképességük miatt, amely gátolja a pórusok fluidumainak kiszorulását. Ha a túlnyomás eléri a horizontális nyomást, a pelit megrepedezik, és lehetőséget ad a képződött szénhidrogének eltávozására. Ez a cikk két példát közöl: primer migráció középső miocén anyakőzetekből és az Endrődi Formációból. Feltételezhető, hogy a vékony középső miocén anyakőzetek a megfelelő mértékű túlnyomás létrejötte miatt repedtek meg, amikor a Zagyvai Formáció lerakódása zajlott. Ezt az eseményt követően a szénhidrogének vertikálisan migráltak a kisebb mélységben elhelyezkedő tárolóikba – létrehozva a Budafa és Lovászi mezőket. A vastag Endrődi Formáció jó anyakőzetnek bizonyult, de szénhidrogénjei nem képeztek felhalmozódásokat az Algyő szerkezeten a Makói-árok nyugati szegélyén az olaj-anyakőzet korreláció eredményei szerint. Feltételezhető, hogy az Endrődi Formáció megrepedése nem következett be a túlnyomás korai megjelenése és a zárórétegek miatt, amelyek a formáció tető és fekü részein jöttek létre.
Социально-психологические функции комплимента в межличностном общении
Authors: Цахилова Камилла О.
Published: April 2021

В статье рассматривается комплимент как важный компонент межличностного общения. В разделе Введение автором раскрывается актуальность исследуемой темы в связи с проблемой установления и поддержания отношений между людьми, их дальнейшей гармонизацией, достижением эффективного бесконфликтного взаимодействия. В теоретическом обосновании автором приводится обзор основных подходов к рассмотрению феномена комплимента в отечественных и зарубежных исследованиях; включая вопросы сходства и различия комплимента, лести и похвалы; влияния комплиментов на качество и характер общения. Новизна исследования заключается в выделении и систематизации функций комплиментов в межличностном общении, описании и структурировании их формально-содержательных характеристик, анализе соотношения со сходными речевыми высказываниями. Поскольку данное явление изучается также в лингвистике, это обусловило междисциплинарный характер его рассмотрения: в русле социально-психологического и лингвистического знания. В разделе Обсуждение результатов автором выделяются основные направления исследования российских и иностранных авторов, которые позволяют говорить о важности комплиментов в межличностном взаимодействии. В заключении в качестве основных, наиболее важных, функций, которые выполняет комплимент, выделяются такие, как: 1) установление и поддержание доброжелательных отношений или гармонизация межличностных отношений; 2) оказание эмоциональной поддержки; 3) соблюдение этикета; 4) доставление удовольствия собеседнику; 5) удовлетворение потребностей партнера в признании и одобрении; 6) конструктивная или созидательная (в конфликтном дискурсе); 7) оказание психологического воздействия; 8) альтернатива другим речевым актам. Автором подчеркивается недостаточная изученность данной темы, намечаются дальнейшие перспективы исследования.
Междисциплинарный подход к изучению дисграфии и дислексии у младших школьников в условиях цифровизации
Authors: Мацюк Елена А.
Published: April 2021

Во введении раскрывается специфика коммуникативной деятельности современных школьников, рассматривается её новый вид – дисплейная коммуникация. Разбираются случаи недостаточной сформированности коммуникативных навыков у обучающихся, имеющих речевые расстройства. Отмечается важность учёта особых образовательных потребностей, психологических и познавательных барьеров в обучении у этой категории школьников. Научная новизна статьи заключается в расширенном анализе структуры, профилактики и преодоления дисграфии с точки зрения междисциплинарного подхода, включающего неврологический, нейропсихологический аспекты и базовые дефектологические логопедические методы диагностики и коррекции нарушений письма и чтения. В теоретическом обосновании содержится обзор отечественных и зарубежных работ, посвящённых нарушениям письма и чтения – дисграфии и дислексии. Сопоставлены результаты исследований, социальных опросов, проводимых российскими и зарубежными специалистами, изучающими проблему. Раскрывается понятие школьной дезадаптации у детей младшего школьного возраста. Понимание структуры нарушений процессов письма и чтения анализируется в парадигме нейропсихологического подхода к их диагностике и коррекции и с учётом психологических особенностей учеников этой категории. В обсуждении результатов обобщаются результаты исследований неврологов, логопедов, нейропсихологов в России и за рубежом, изучивших на современном этапе причины и многофакторную структуру дисграфии и дислексии и указывающих на особое значение целенаправленного комплексного междисциплинарного подхода в преодолении этих расстройств. Показана важность объединения воздействий не только на когнитивную, эмоциональную и поведенческую сферу обучающихся с дисграфией и дислексией, но прежде всего понимание всего симптомокомплекса, частью которого являются эти расстройства, а также учёт медико-биологических факторов. Результативность коррекционных программ, по мнению авторов, зависит от наличия стойкого интереса учеников к процессу обучения, формирование которого невозможно сегодня без использования привычных поколению «цифры» достижений информационного общества, таких как сетевые ресурсы и дисплейная коммуникация, успешно используемые в современном образовательном пространстве.
KUALITAS FISIK DAGING BROILER DI PASAR TRADISIONAL KOTA BANDAR LAMPUNG
Authors: Ardiansyah Aji , Riyanti Rr. , Septinova Dian , Nova Khaira
Published: April 2021

Broiler meat is one of the most common sources of animal protein consumed by Indonesians. This study aimed to determine the physical quality of broiler meat including pH value, water holding capacity, and cooking losses of broiler meat in the traditional market of Bandar Lampung city. This research was conducted in December 2019--January 2020. This research used a survey method using 79 samples of breast broiler meat. The sample was from 13 traditional markets in the city of Bandar Lampung (Rajabasa market, Untung market, SMEP market, Koga market, Way Kandis market, Way Halim market, Tugu market, Tamin market, Kangkung market, Cimeng market, Lempasing market, Gudang Lelang market, and Panjang market). The variables observed in this study included degree of Power of Hydrogen (pH), water holding capacity (WHC), and cooking losses. The results of this study indicated that the highest pH value (6.04) was from the Lempasing market, the lowest pH value (6.138) was from Gudang Lelang market, the highest WHC value was from the Lempasing market which was 58.13%, the lowest WHC value was from Way Kandis market which was 52.76%, the highest cooking loss value was obtained from the SMEP market which was 31.48%, and the lowest cooking loss value was obtained from the Rajabasa market which was 27.29%. It can be concluded that the pH value and cooking loss were still normal with an average range of 6.138-- 6.304 and 27.29--31.48%, respectively, while the average range of water holding capacity was in high category (52.76--58.13).

Keywords: Broiler, Cooking loss, pH, Traditional market, Water holding capacity
Analysis of damage failure in uniaxial compressive of cemented paste backfill by ultrasonic pulse velocity test
Authors: Wang B. , Li L. , Yu Y. , Huo B. , Liu J.
Published: April 2021

Cemented paste backfill (CPB) is prepared by mixing cementitious materials, tailings and water. Uniaxial compressive strength (UCS) is one of the most commonly used indicators for evaluating the mechanical performance of CPB. Ultrasonic pulse velocity (UPV) testing which is a non-destructive measurement, can also be applied to determine the mechanical properties of cement-based materials such as CPB. In order to study the failure mechanism of CPB,144 CPB samples prepared at different mass fraction and cement-tailing ratios were subjected to the UCS and UPV tests at 7,14 and 28 days of curing age. The effect of cement-tailing ratio and mass fraction on the UCS and UPV of CPB samples were obtained, the UCS values were correlated with the corresponding UPV data. Microstructural analysis was also performed on CPB samples to understand the effect of microstructure on the UCS data. The results show that the UCS and UPV values of CPB increased with cement-tailing ratio, mass fraction and curing time. Based on the experimental results, the damage constitutive equations and the damage evolution equations of different backfills were proposed on the basis of damage mechanics. Moreover, comparative analysis of constitutive model and experimental results were made to verify the reliability of the damage model. The results acquired by this paper provide a scientific basis for the rational strength design of backfill mine.
Simulation Model to Determine Ratios between Quay, Yard and Intra-Terminal Transfer Equipment in an Integrated Container Handling System
Authors: Sha Mei , Notteboom Theo , Zhang Tao , Zhou Xin , Qin Tianbao
Published: April 2021

This paper presents a generic simulation model to determine the equipment mix (quay, yard and intra-terminal transfer) for a Container Terminal Logistics Operations System (CTLOS). The simulation model for the CTLOS, a typical type of discrete event dynamic system (DEDS), consists of three sub-models: ship queue, loading-unloading operations and yard-gate operations. The simulation model is empirically applied to phase 1 of the Yangshan Deep Water Port in Shanghai. This study considers different scenarios in terms of container throughput levels, equipment utilization rates, and operational bottlenecks, and presents a sensitivity analysis to evaluate and choose reasonable equipment ratio ranges under different operational conditions.
Factors that Contribute to the Reduction of Participation in Sports Activities Among University Students
Authors: Olănescu Mihai
Published: April 2021

"ABSTRACT. Introduction: In this article, our aim is to examine the main
reasons that lead university students to practice less and less physical sports
activities. Objective: Identifying the differences that may exist between students
who were enrolled at the Technical University of Cluj-Napoca, in the academic
year 2011-2012, and those who were enrolled in the academic year 2019-2020,
regarding the reasons that determine them to reduce the time allocated to
physical sports activities. Methods: To find out why the level of participation
of university students in various physical sport activities is very low, and tends
to decrease from year to year, we conducted two studies, the first one in the
2011-2012 academic year (n=880 participants), and the second one, in the
academic year 2019-2020 (n=594 participants), and we compared the results
obtained. Results: The results of the study show the reasons for today’s short
time allocated by students to physical activities and the reasons why they are
too busy to play sports. The findings indicate that the main reason why
students of the Technical University of Cluj-Napoca practice less and less
physical sports activities is because they are busier. The overloaded program
from university is the main cause why some students have reduced the time
allocated to sports activities. Other important factors are the lack of energy and
the lack of sport facilities. Conclusions: Increasing educational requirements
and reduced leisure time, justify a decrease in students’ interest in participating
in extracurricular sports activities. To increase the motivation and future sport
adherence of students, it would be necessary for universities and local public
authorities to provide a motivational climate for practicing physical activities
and sport."
The Influence of Biofeedback in Postural Rehabilitation of Athletes
Authors: Chelaru Hajnal , Bulduş Codruța Florina , Monea Dan
Published: April 2021

"ABSTRACT. Background. A balanced posture allows sports movements
PERFORMANCE with optimal consumption of energy and minimal stress on the
musculoskeletal system with of the technology offered by the posturograph, we
can identify the center of gravity deviations, the points of support, the load, the
weight distribution in the soles, the anterior posteriorized or compressed
posture, the asymmetries of the body. by an interpretation in biomechanical
context, any compensations or decompensations can be identified. Aim. The
aim of the study is to improve posture through biofeedback treatment using
the GPS 600 device. Materials. The Posturograph or Global Postural System
(GPS) is an advanced postural analysis system that uses techniques and
methods of noninvasive diagnosis and evaluation in the field of medical
recovery. Posturography includes 2 diagnostic units and software. Methods.
We used the following methods: bibliographic study methods, method of
observation, measurement method, experimental method, statistical method.
Applied treatments. The treatments for re-educating the posture with the GPS
600 device took place for 2 weeks. During the treatment, the subjects had to
maintain their body position / posture as indicated by the device. Results.
From the 12 athletes, the anteriority of the head improved, the center of
gravity, loading on the right and left lower limbs. At the end of the 2 weeks, the
athletes reached a perfect balance of the center of gravity and the weight
distribution on the lower limbs. Conclusion. Biofeedback treatments with the
GPS 600 device help to improve POSTURE and maintain the results over time."
Sobre el aprovechamiento de recursos de origen animal en la región de Madrid durante el III milenio cal. AC: la fauna de los contextos calcolíticos del Sector 3 de Las Cabeceras (Pozuelo de Alarcón, Madrid)
Authors: Moreno García Marta , Cantalapiedra Jiménez Víctor
Published: April 2021

Se presenta el análisis de un pequeño conjunto faunístico recuperado en las excavaciones del Sector 3 del yacimiento de Las Cabeceras, localizado en Pozuelo de Alarcón, Madrid. El material procede de los rellenos de 32 estructuras semisubterráneas de cronología calcolítica (primera mitad del III milenio cal. AC.) El espectro faunístico refleja el aprovechamiento de recursos ganaderos y en menor medida, de especies silvestres entre las que destaca el ciervo, los équidos y el uro. El sacrificio mayoritario de animales adultos y seniles sugiere el mantenimiento de cabañas ganaderas orientadas a la diversificación productiva (carne, lana, lácteos, piel, fuerza de trabajo, abono de los campos, etc.), si bien en el caso del porcino la ausencia de inmaduros y el dominio de cerdas de avanzada edad podría reflejar la producción de lechones destinados al intercambio entre asentamientos del ámbito local o regional. Igualmente, cabe destacar la contribución relativamente elevada de herbívoros silvestres de porte grande en relación a otros yacimientos coetáneos del centro peninsular.
Sistema de Informações Geográficas como ferramenta de análise espacial e tabular para a implantação de praças e parques urbanos | Geographical information system as a tool for spatial and table analysis for the implementation of public squares and urban parks
Authors: Cocco Renata Michelon , Aita Pippi Luis Guilherme , Weiss Raquel
Published: April 2021

Este artigo visa apresentar o recorte da pesquisa de mestrado sobre a identificação de espaços livres potenciais para a implantação de praças e parques urbanos da cidade média de Santa Maria (Rio Grande do Sul, Brasil). Através do uso de ferramentas de um Sistema de Coordenadas Geográficas, a análise sistêmica de geodados espaciais (cartográficos) e alfanuméricos (tabulares) é utilizada para analisar a espacialização e cruzamento de parâmetros ambientais, de equipamentos comunitários e de informações socioeconômicas existentes na cidade. A partir do cruzamento de informações sobre os raios de atendimento de praças e parques com dados de população e renda, pode-se delimitar onde existem déficits de áreas de lazer e recreação na cidade. A análise dos resultados permite avançar em uma proposta geral de diretrizes que devem estar de acordo com as deficiências, condicionantes e potencialidades de cada região de Santa Maria, a fim de que esses equipamentos sejam implantados no futuro por meio de estratégias urbanísticas e que sejam preservados a partir de um eficiente sistema de gestão e manutenção.
O ensino superior no município de Canoinhas
Authors: Gumbowsky Argos , Pacheco Luiz Antonio
Published: April 2021

Este artigo resulta de pesquisa cujo objetivo foi investigar o percurso histórico de implantação da educação superior no município de Canoinhas no período compreendido entre 1990 e 1999 e as contribuições para o desenvolvimento regional. Utilizou-se da pesquisa documental. A principal fonte da pesquisa documental foi o Jornal Correio do Norte. Justificou-se o estudo pela comemoração do cinquentenário da Instituição no município de Canoinhas. As principais ações recaíram em programas de extensão e pesquisa, qualificando assim o ensino dos acadêmicos e consolidando o verdadeiro espirito de uma Universidade que se estrutura no tripé: ensino, pesquisa e extensão, como fomentadora do desenvolvimento regional.
Palavras-chave: Universidade do Contestado. Educação Superior, município de Canoinhas, desenvolvimento regional.
Effect of Lower Back Extensors Fatigue on Athletic Performance Measured as Agility
Authors:   Associate Professor, Department of Rehabilitation Sciences, SNSAH, Jamia Hamdard,New Delhi, India, Zutshi Kalpana
Published: April 2021

Background: At high level of competition, sports require long periods of hard physical work. Each athlete should be able to perform desired actions efficiently, which will not be possible without coordinated activation of muscles in the kinetic chain. EMG studies demonstrate that lumbar paraspinal muscles fatigue is associated with Quadriceps Inhibition (QI), leading to speculation that these changes may not only have adverse effect for athletic performance but also increase the risk of injury in long term. This contrasts the evidence about the influence of fatigue on trunk muscles reflex activity. Method: 37 athletes (men) were recruited from city soccer clubs. The participants performed sub maximal isometric exercise of lower back extensors (Ito’s test) to induce fatigue. The two protocols were a single bout and repeated bouts of Lumbar Extension Isometric Exercise (LEIE). The Agility scores recorded at baseline, after single bout and after repeated bouts of LEIE were compared. Conclusion: The two experimental interventions differently affected the agility performance in the sample. On one hand, single bout intervention led to improved performance, repeated bout intervention resulted in relative deterioration of performance.
Development and validation of a flow cytometric assay for detecting reactive oxygen species in the erythrocytes of healthy dogs
Authors: Woolcock Andrew D. , Serpa Priscila B. S. , Santos Andrea P. , Christian John A. , Moore George E.
Published: April 2021

OBJECTIVE

To validate the use of a flow cytometric assay that uses 2‘,7‘-dichlorodihydrofluorescein diacetate (DCFH-DA) to measure reactive oxygen species in the erythrocytes of healthy dogs.

ANIMALS

50 healthy adult dogs.

PROCEDURES

Erythrocytes were incubated with DCFH-DA or a vehicle control (dimethyl sulfoxide), then incubated with (stimulated) or without (unstimulated) hydrogen peroxide. The flow cytometric assay was evaluated for specificity with increasing concentrations of DCFH-DA and hydrogen peroxide, and a polynomial regression line was applied to determine optimal concentrations. For precision, samples were analyzed 5 consecutive times for determination of intra- and interassay variability. Stability of samples stored at 4°C for up to 48 hours after blood collection was determined with flow cytometric analysis. Coefficient of variation (CV) was considered acceptable at 20%. Baseline measurements were used to determine an expected range of median fluorescence intensity for unstimulated erythrocytes incubated with DCFH-DA.

RESULTS

Erythrocytes were successfully isolated, and stimulated samples demonstrated higher median fluorescence intensity, compared with unstimulated samples. The intra-assay CV was 11.9% and 8.9% and interassay CV was 11.9% and 9.1% for unstimulated and stimulated samples, respectively. Unstimulated samples were stable for up to 24 hours, whereas stimulated samples were stable for up to 48 hours.

CONCLUSIONS AND CLINICAL RELEVANCE

Flow cytometry for the measurement of reactive oxygen species in the erythrocytes of healthy dogs by use of DCFH-DA had acceptable specificity, precision, and stability. Flow cytometry is a promising technique for evaluating intraerythrocytic oxidative stress for healthy dogs.
Assessment of the physical compatibility of injectable enrofloxacin with commonly used intravenous fluids and drugs during simulated Y-port administration
Authors: Aghili Anahita , Thomovsky Elizabeth J. , Johnson Paula A. , Brooks Aimee C. , Pierce Trinna J. , Gochenauer Alexandria E.
Published: April 2021

OBJECTIVE

To evaluate physical compatibility of small animal (SAE) and large animal (LAE) injectable formulations of enrofloxacin with select IV fluids and drugs.

SAMPLE

162 admixtures containing SAE or LAE with saline (0.9% NaCl) solution, lactated Ringer solution (LRS), Plasma-Lyte A (PLA), 6% hydroxyethylstarch 130/0.4 (HES), metoclopramide, or ampicillin-sulbactam.

PROCEDURES

In the first of 2 simultaneously conducted experiments, admixtures containing enrofloxacin (10 mg/kg) and a volume of IV fluid that would be administered over a 20-minute period when dosed at the maintenance infusion rate (40 mL/kg/d for saline solution, LRS, and PLA and 20 mL/kg/d for HES) were created. In the second experiment, enrofloxacin (10 mg/kg) was admixed with saline solution (40 mL/kg/d) and metoclopramide (2 mg/kg/d) or ampicillin-sulbactam (30 mg/kg). In both experiments, admixture components were infused into a flask over 20 minutes assuming patient weights of 5, 10, and 20 kg. Admixtures were created by use of undiluted SAE and SAE diluted 1:1 with saline solution and undiluted LAE and LAE diluted 1:1 and 1:10 with saline solution. Admixtures were assessed for physical incompatibility at 0, 15, 30, and 60 minutes after completion of mixing. Physical incompatibility was defined as gross precipitation, cloudiness, Tyndall effect, or change in turbidity.

RESULTS

Admixtures containing undiluted SAE or LAE were physically incompatible with saline solution, PLA, LRS, and HES. Because saline solution was used to dilute SAE and LAE, all admixtures containing diluted SAE or LAE were also physically incompatible. Physical compatibility of enrofloxacin with metoclopramide or ampicillin-sulbactam could not be assessed because those admixtures also contained saline solution.

CONCLUSIONS AND CLINICAL RELEVANCE

Enrofloxacin was physically incompatible with all tested solutions.
Effect of withholding food on serum concentrations of cobalamin, folate, trypsin-like immunoreactivity, and pancreatic lipase immunoreactivity in healthy dogs
Authors: Saver Alexander T. , Steiner Jörg M. , Hetzel Scott J. , Lidbury Jonathan A. , Suchodolski Jan S. , Pritchard Jessica C.
Published: April 2021

OBJECTIVE

To evaluate the effects of withholding food on the results for measurements of serum concentrations of cobalamin, folate, canine pancreatic lipase immunoreactivity (cPLI), and canine trypsin-like immunoreactivity (cTLI) in healthy dogs.

ANIMALS

11 healthy employee- or student-owned dogs.

PROCEDURES

Food was withheld from the dogs for 12 hours, baseline blood samples were collected, then dogs were fed. Postprandial blood samples collected 1, 2, 4, and 8 hours later were assessed. A mixed-effects ANOVA model with fasting duration (time) as a fixed factor and dog as a random effect was fit for each analyte variable. Additionally, a mixed-effects ANOVA model controlling for the variable of time was fit to assess whether lipemia affected serum concentrations of the analytes.

RESULTS

The median serum cobalamin concentration was lower at 4 hours (428 ng/L) and 8 hours (429 ng/L) postprandially, compared with baseline (479 ng/L), but this difference was not clinically meaningful. Although there were no substantial differences in serum concentrations of folate, cPLI, or cTLI, postprandial changes in serum concentrations of cTLI or folate could potentially affect diagnoses in some dogs.

CONCLUSIONS AND CLINICAL RELEVANCE

Although results indicated that feedings rarely resulted in clinically important differences in the median serum concentrations of cobalamin, folate, cPLI, or cTLI in healthy dogs, given the further processing required for lipemic samples, withholding food for at least 8 hours is an appropriate recommendation when measuring these analytes. Similar research is needed in dogs with gastrointestinal disease to determine whether the withholding of food is necessary when measuring these analytes in affected dogs.
Synthesis and Correlation of Aggregation and Antimicrobial Properties of Homochiral Quaternary Ammonium Bromides Derived from Camphoric Acid
Authors: Mikláš R. , Miklášová N. , Bukovský M.
Published: April 2021

A group of homochiral quaternary ammonium salts bearing hydrophobic camphoric acid-derived moiety was synthesized and characterized. The aggregation properties of the prepared compounds were evaluated by surface tension measurements, and the critical micelle concentration (CMC) was calculated. The novel quaternary ammonium bromides were tested as antimicrobial and antifungal agents, and their minimal inhibitory concentration (MIC) was evaluated and compared to clinically used benzalkonium bromide (BAB). Correlation of MIC with CMC reveals that monomers of prepared cationic surfactants, instead of micelles, are primarily responsible for antimicrobial activity.
Dril Procedure: Treatment for Vascular Access Induced Hand Ischemia. Case Report
Authors: Helgiu Claudiu
Published: April 2021

Native vascular access (AVF arteriovenous fistula) for chronic hemodialysis (CH) performed proximally to the diabetic patient, between the brachial artery and the basilic vein or cephalic vein, determines the risk of distal (hand) ischemia. The correction of the ischemia can be done differently depending on its severity, starting from the vasodilator medication, reaching the cancellation of the vascular access with the accomplishment of the chronic hemodialysis on the central venous catheter. DRIL procedure (Distal Revascularization and Interval Ligation) corrects distal ischemia while maintaining functional vascular access, an important aspect in diabetic patients in whom vascular capital is deficient. We further describe a case of a diabetic patient with right L-T brachiocephalic arteriovenous fistula, with important ischemic phenomena in which the DRIL procedure resolved the ischemia, the patient using vascular access as usual, the second postoperative day.
The Damage of Ocular Surface Due to Uncontrolled Intraocular Pressure in Neovascular Glaucoma
Authors: Panga Alina-Adriana , Stănilă Dan Mircea , Stănilă Adriana , Jurcă Alexandra
Published: April 2021

Neovascular Glaucoma (NVG) is a severe form of glaucoma characterized by neovascularization and the proliferation of fibrovascular tissue in the anterior chamber angle. Patients with NVG generally present with elevated intraocular pressure (IOP) and may experience severe pain. Ocular surface is affected by high IOP and can lead from moderated to marked conjunctival congestion that is frequently associated with edematous cornea. The aim of the study is to show how the high IOP can affect the ocular surface of the NVG patients and how we can treat and prevent the suffering. Materials and methods: We took in the study a number of 38 eyes from 35 patients with NVG in stage 3 with angle closure glaucoma, that presented high IOP and impaired ocular surface. Results and discussions: The ocular surface was damaged in patients that presented IOP between a minimum of 38 mmHg and maximum of 89 mmHg. The symptoms that patients presented were: conjunctival congestion in particular perikeratic, epithelial and stromal corneal edema, epithelial bubble, corneal ulcerations. Treatment followed rapid drop in IOP and the restoration and protection of ocular surface. The management of neovascular eye with high IOP was medical, laser and surgical. The restoration of ocular surface was made with lubricating hyperosmotic ophthalmic solutions, regenerative and protective agents. In all cases after the treatment was performed the ocular surface was restored. Conclusions: NVG is a very difficult pathology and is very hard to manage. The uncontrolled IOP in NVG patients affect the ocular surface and leads to complications. Long-term maintenance of normal intraocular pressure is important in NVG management but also in protecting the ocular surface.
Predictive Biological Markers for Anastomotic Leakage after Curative Surgery for Colorectal Cancer
Authors: Bimbó-Szuhai Erika , Maghiar Adrian , Huniadi Anca , Șandor Mircea , Botea Mihai , Macovei Codruța , Beiușan Corina , Pusta Claudia Teodora Judea
Published: April 2021

anastomotic leakage is one of the most important postoperative complications for colorectal cancer patients undergoing curative surgery. Early recognition of patients in risk would be essential for preventing the high mortality rates associated with these complications. C reactive protein (PCR), tumour necrosis factor (TNF-alpha), cortisol levels and granulocyte/lymphocyte ratio (G/L) were compared in this period in patients who developed leakage vs patients without this complication. Material and methods: 52 colorectal cancer patients who underwent elective surgery in a private clinical hospital were evaluated preoperatively and postoperatively for the patients. Results: 14 patients (26,9%) developed clinically significant anastomotic leakage. The best cut-off value for preoperative G/L ratio of 5,8 had sensitivity of 71,43% and specificity of 73,68%. Conclusions: Preoperative G/L ratio can be used as a largely available tool for identifying the colorectal cancer patients at high risk for anastomotic leakage.
Treatments’ Complexity in Dental Care Assistance, Urban Versus Rural Environment - Preliminary Study
Authors: Ionescu Camelia , Malița Mădălina Adriana , Perieanu Viorel Ștefan , Burlibașa Mihai , Dina Magdalena Natalia , Costea Radu , Perieanu Mădălina Violeta , Costea Raluca , Babiuc Iuliana , Beuran Irina Adriana , Tănase Gabriela , Chirilă Mihaela , Voinescu Ioana , David Mihai , Moraru Liliana
Published: April 2021

When talking about dental assistance we actually refer to the prevention, detection and treatment of diseases of the oral and maxillo-facial region which, in most cases, have as a starting point or interest the dento-maxillary system. In this material, we tried to present a comparative study on the typology and complexity of different stages of dental treatments that can be performed in urban areas, compared to various stages of dental treatments that are performed and / or could be made in rural dental offices from in Romania.
Malformative Reno-Urinary Pathology in Patients with HIV Infection-Clinical and Therapeutic Implications
Authors: Gabriela Sotila Gianina , Elena Dumea , Roxana Cernat , Irina Dumitru Magdalena , Sorin Rugina
Published: April 2021

Chronic kidney disease is an important comorbidity of HIV infection causing real problems in the evolution and medical healthcare of HIV-positive patients. In recent years, a significant number of HIV-positive patients develop renal dysfunction, several mechanisms being incriminated: direct effect of the virus, toxic effect secondary to of antiretroviral medication, secondary to associated comorbidities, given that life expectancy has increased significantly in the last decade, thanks to the use of antiretroviral therapies. There are few studies in the literature to evaluate malformative renourinary pathology in patients with HIV infection. We present the case of a patient with HIV infection, horseshoe kidney, chronic kidney disease and incomplete Fanconi syndrome, secondary to the administration of tenofovir fumarate, a nucleoside reverse transcriptase inhibitor. Malformations, abnormalities or dysmorphysms of the renal tract should be considered in the HIV-positive patient with secondary renal dysfunction because they take a wide range of forms, are underdiagnosed and predispose to multiple complications, with varying degrees of severity, such as urinary tract infections, renal stones or progression of chronic kidney disease. Tenofovir fumarate and atazanavir must be avoided in patients with HIV infection and chronic renal dysfunction.
Laparoscopic Gastrectomy with D2 Lymphadenectomy for pT1a Adenocarcinoma: Case Report and Literature Review
Authors: Cristina Dan , Vasile Sarbu , Catalin Popescu Razvan , Ovidiu Costea Daniel , Gentiana Micu Luminita , Manuela Enciu
Published: April 2021

Gastric cancer is one of the most common malignancies, associated with a high mortality and morbidity rate, especially in the elderly, the fourth leading cause of cancer mortality in Europe. Although the rate of diagnosis has declined in recent years, the prognosis of the disease and the mortality rate is still quite high. Laparoscopic surgery, accompanied by lymphadenectomy, is a curative method of treatment, used more and more frequently, especially in Eastern countries, both in the incipient disease and in advanced stages of the disease, which has many advantages over classical surgery.

We report the case of an 86-year-old man, who presented for marked physical asthenia, weight loss and severe anemia, in whom we performed laparoscopic distal radical gastrectomy with D2 lymphadenectomy and Roux-en-Y reconstruction. Histopathological examination established the diagnosis of low-grade / well-differentiated tubular adenocarcinoma G1 (WHO) / intestinal carcinoma (Lauren), with invasion in the lamina propria, developed on an intestinal-type adenoma. 21 lymph nodes were taken without tumor invasion.

This case highlights the complexity of laparoscopic intervention, with the proven advantages for the patient, like reduced surgical trauma and pain, with the decrease of postoperative complications, but also the difficulty of the surgical technique which requires advanced laparoscopic skills. Thus, in addition to its proven efficacy in cases of early gastric cancer, the technique can be extended to advanced malignancies, without affecting the oncological safety limit.