bluuebunny/crossref_metadata_2025 huggingface dataset:
Carrydown of liquid friction modifier
Authors: Rahmani Hatef , Gutsulyak Dmitry , Stanlake Louisa , Stoeber Boris , Green Sheldon
Published: March 2022

A small-scale laboratory apparatus was built to study liquid friction modifier (LFM) behavior in a top-of-rail application. A field experiment was also carried out to complement the laboratory findings. KELTRACK® (a water-based LFM) was used as the test fluid. Laser-induced fluorescence served to measure the LFM thickness left on the track after the passage of the wheel. The lab experiments show that the LFM cannot withstand the high wheel-rail contact pressure in the nip present in cargo rail situations. As a result, the liquid is squeezed out laterally and attaches to the edges of the wheel contact band. This “edge liquid” is then carried down the track on the wheel. Gravimetric measurements of the wheel contact band confirm this observation, and show that only a minute amount of liquid is carried through the nip in the valleys between surface roughness features. In the field experiment, the LFM is applied from a trackside unit on a tangent section of the track. About 500 m downstream of the application point, the track has a curved section. LFM cannot be detected anywhere on the track a short distance (∼200 m) past the application unit. However, LFM is detectable on the curved sections of the track up to approximately 2 km from the application unit. This LFM on the curved track is believed to be due to transfer of the “edge liquid” from the wheel to the track, caused by the movement of the contact band as the train rounds a curve. The presence of LFM on the curved track far downstream is consistent with prior measurements of reduced lateral force on the curved track downstream of LFM application sites.
Hydroxychloroquine increased cholesterol transfer to high-density lipoprotein in systemic lupus erythematosus: A possible mechanism for the reversal of atherosclerosis in the disease
Authors: Lang Maria G , Vinagre Carmen GC , Bonfa Eloisa , Freitas Fatima R , Pasoto Sandra G , Brito Tatiane S , Seguro Luciana PC , Maranhão Raul C , Borba Eduardo F
Published: March 2022

Introduction

The beneficial effect of hydroxychloroquine (HCQ) in decreasing LDL levels on Systemic Lupus Erythematosus (SLE) is well defined. The influence of this drug on HDL levels is still under debate and information about its effect on cholesterol reverse transport is lacking.

Objective

To evaluate the effects of HCQ on HDL levels and the transfer of lipids to this lipoprotein in SLE.

Methods

Nineteen SLE patients using only HCQ (SLE WITH HCQ), 19 SLE patients without any therapy (SLE WITHOUT THERAPY), and 19 healthy controls (CONTROL) were included. All three groups were premenopausal women age- and gender-matched. Serum lipids and apolipoproteins were determined by commercial kits. An in vitro transfer of four lipids (14C-Phospolipid, 3H-Cholesteryl ester, 3H-Triglyceride, and 14C-Unesterified cholesterol) from a radioactively labeled nanoemulsion donor to HDL was performed in all participants.

Results

Groups had comparable mean age, weight, height, BMI(body mass index), and waist circumference ( p > .05). Mean HDL levels were higher in SLE WITH HCQ group compared to SLE WITHOUT THERAPY(58.37 ± 14.04 vs 49.79 ± 8.0 mg/dL; p < .05) but lower than CONTROL (58.37 ± 14.04 vs 68.58 ± 9.99 mg/dL; p < .05). Total cholesterol (TC) and LDL levels were also significantly lower in SLE WITH HCQ compared SLE WITHOUT THERAPY(148.16 ± 16.43 vs 167.11 ± 30.18 mg/dL; p < .05, 75.05 ± 22.52 vs 96.05 ± 25.63 mg/dL; p < .05) and CONTROL (148.16 ± 16.43 vs 174.11 ± 23.70 mg/dL; p < .05, 75.05 ± 22.52 vs 88.53 ± 20.24 mg/dL; p < .05). The in vitro lipid transfer to HDL study revealed a significant difference among the three groups ( p = .002) with a higher transfer of unesterified cholesterol(UC) in SLE WITH HCQ compared to SLE WITHOUT THERAPY(5.40 ± 1.05% vs. 4.44 ± 1.05%; p < .05). The latter was significantly decreased compared to CONTROL (5.40 ± 1.05% vs. 5.99 ± 1.71%; p < .05).The percentages of transfer of triacylglycerol (4.93 ± 0.69% vs. 4.50 ± 0.69% vs. 5.14 ± 1.01%; p = .054), esterified cholesterol (5.24 ± 0.70% vs. 4.96 ± 0.89% vs. 5.69 ± 1.27%; p = .079), and phospholipid (15.67 ± 1.03% vs. 15.34 ± 1.44% vs. 16.47 ± 1.89%; p = .066) were similar among groups.

Conclusion

The present study is the first to demonstrate that HCQ promoted a higher transfer of unesterified cholesterol which may account for the increased HDL levels in lupus patients under HCQ. This desirable effect may underlie the reported reduced atherosclerosis in SLE.
Neonatal Encephalitis and White Matter Injury in an Early Neonate: Cause or Association With COVID-19 Infection?
Authors: Khamkar Anilkumar , Suryawanshi Pradeep , Pote P. D. , Jose Georgeena Elsa
Published: March 2022

Coronavirus disease 2019, caused by severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) has demanded world’s attention. Though this disease affects all age groups, for reasons unknown at this time, neonates and children seem to be at a lower risk of severe infection. We report the first case of neonatal SARS CoV-2 encephalitis in Pune, India and review the related published articles. A 4-day-old, previously healthy, full-term neonate was hospitalized for poor feeding and repeated episodes of focal convulsions since 104 h of life. Keeping in mind the rampant community transmission, SARS-CoV-2 rapid antigen detection and polymerase chain reaction testing was done, where both turned out to be positive. There were elevated inflammatory markers, cerebrospinal fluid pleocytosis, and acute splenial lesions in the magnetic resonance imaging of the brain consistent with neonatal SARS CoV-2 encephalitis. The baby recovered completely with no recurrence and was discharged home in 2 weeks.
The Legacy of the Life and Work of Lotika Sarkar
Authors: Muralidhar S.
Published: March 2022

Based on a talk by the author, the article seeks to sketch the work and contribution of Professor Lotika Sarkar, the first woman law teacher of the Delhi University. A much sought after teacher, with a progressive outlook, Professor Sarkar mentored several generations of law scholars, teachers and judges. The article speaks of Professor Sarkar’s seminal contribution as member of the Committee on the Status of Women in India. Her chapter on ‘women and the law’ formed a significant part of the Committee’s 1975 report. Professor Sarkar joined three other eminent law teachers in penning an Open Letter to the Chief Justice of India, on September 16, 1979, in the wake of the Tukaram case. This letter paved the way for significant changes in law relating to custodial rape. The issues that Professor Sarkar worked on are of contemporary relevance to any serious legal scholar looking for a reference point, and the right questions to ask.
Female elite sports achievements in Iran. The Case of the First Olympic Medalist
Authors: Ziaee Ali , van Sterkenburg Jacco , van Hilvoorde Ivo
Published: March 2022

The present study aims to identify the societal implications of the first-ever Iranian female medalist in the Olympics to date. We explored the meanings given to Kimia Alizadeh's success within Iranian society. We collected data through an examination of online news agencies and social networking sites using Leximancer software, a computer-assisted program for qualitative content analysis. This analysis uncovered four main themes: ‘women's sports and the dynamics of local-global policy’, ‘hope and determination’, ‘pride in light of hijab’, and ‘meaningful and historic medal’. It was concluded that the societal implications of this medal-winning are more important than the quality of the medal itself within Iranian society. We also suggest assessing Iranian sportswomen within their own socio-cultural context.
Industrial policy and comparative political economy: A literature review and research agenda
Authors: Bulfone Fabio
Published: March 2022

The Great Recession renewed calls for a return of state activism in support of the European economy. The widespread nationalizations of ailing companies and the growing activism of national development banks led many to celebrate the re-appearance of industrial policy. Despite this reappraisal, however, comparative political economy (CPE) contributions to the study of industrial policy are still scarce. This review article critically overviews the existing literature linking CPE and industrial policy meeting three goals. First, to trace the evolution of the goals, protagonists, and policy instruments of industrial policy in the European Union (EU) since the post-war period. Second, to provide a periodization of the evolution of industrial policy based on the distinction between the inward-looking forms of state intervention prevalent until the late 1970s and the open-market industrial policy of later decades. Third, to outline future research pathways based on the integration between CPE, heterodox economics, and economic geography.
Outcomes of a co-located approach for metabolic health care for people with schizophrenia
Authors: Siskind Dan , Yen Wesley , Thuzar Moe , Russell Anthony , Warren Nicola , Kisely Steve , Kar Ray Manaan , Motamarri Balaji
Published: March 2022

Objective

Metabolic syndrome is highly prevalent among people with schizophrenia. This study aims to assess the impact on metabolic and attendance outcomes of a co-located, dedicated, endocrinologist-led metabolic clinic in a stand-alone public community mental health service.

Methods

Demographic and metabolic data on the first 48 consecutive referrals over a 12-month period were retrospectively collected and analysed. Attendance rates at the co-located clinic were compared to the general hospital obesity and diabetes clinics.

Results

Clinic attendees had significant reductions in triglycerides and total cholesterol, but not mean weight, BMI, waist circumference, blood pressure or HbA1c. Attendance rates were significantly higher in the co-located clinic compared to the general hospital obesity and diabetes clinics for both initial consult (80.0% vs 51.2%, p < 0.001) and review appointment (64.3% vs 47.6%, p < 0.001).

Conclusion

The co-location of a specialist metabolic clinic within a mental health service resulted in enhanced engagement and improvement of metabolic health in people with schizophrenia.
Evaluation of the scil vCell 5, a novel laser- and impedance-based point-of-care hematology analyzer, for use in dogs and cats
Authors: Zelmer Kim-Lina Charlotte , Bauer Natali , Moritz Andreas
Published: March 2022

A novel laser- and impedance-based point-of-care hematology analyzer (POCA), the vCell 5 (scil Animal Care), providing a complete blood count with 5-part leukocyte differential count has recently been introduced to veterinary laboratories. We evaluated the analyzer for use in dogs and cats including method comparison and assessment of linearity, carryover, and precision. Fresh blood samples from 192 healthy and diseased dogs and 159 cats were analyzed, and results were compared to reference methods (i.e., microhematocrit [PCV], Advia 2120 hematology analyzer). Total observed error (TEo) was calculated from CV, obtained at 3 concentrations, and bias%, and compared to total allowable error (TEa). For both species, excellent correlation (rs = 0.93–0.99) was seen between methods for WBC and RBC, hematocrit, hemoglobin, and platelet counts (PLT), except for feline PLT (rs = 0.79). Quality requirements (TEo < TEa) were fulfilled for WBC (TEo = 8.6–11.1%; TEa = 20%) and RBC (TEo = 3.5–7%; TEa = 10%), hematocrit (TEo = 5.7–9.4%; TEa = 10%), PCV (cat TEo = 7.8%; TEa = 10%), mean corpuscular volume (cat TEo = 5.1%; TEa = 7%), and PLT (TEo = 13.1–24.1%; TEa = 25%). Excellent linearity was demonstrated for WBC, RBC, and PLT, and hemoglobin. CVs of <2% for WBC, RBC, hematocrit, hemoglobin, and of <5% (dog) and 8% (cat) for PLT were demonstrated for values within the RI. Except for calculated variables and well-known species-specific deviations in feline PLT, scil POCA results were correlated favorably with reference method results and complied with quality requirements for cats and dogs.
Separation and Discrimination: The Lived Experience of COVID-19 Survivors in Philippine Isolation Centers
Authors: Romulo Sheilalaine G. , Urbano Ryan C.
Published: March 2022

Social isolation in times of pandemic can affect the well-being of individuals infected with a contagious disease. This study explores the lived experience of the 12 COVID-19 survivors placed in community-based isolation centers in Cebu City, Philippines and whose cases were mild and asymptomatic. In describing their lived experience, we employed Max van Manen's phenomenology of practice. Results show that the COVID-19 survivors have suffered more from the consequences of separation and discrimination than the disease's physiological effects. Educating the whole community about social responsibility and ethical behavior in dealing with COVID-19 survivors is essential to minimize social stigma and discrimination.
SF3B4 Frameshift Variants Represented a More Severe Clinical Manifestation in Nager Syndrome
Authors: Ulhaq Zulvikar Syambani , Soraya Gita Vita , Istifiani Lola Ayu , Pamungkas Syafrizal Aji , Tse William Ka Fai
Published: March 2022

Nager syndrome (NS) is a rare disease marked with craniofacial and preaxial limb anomalies. In this report, we summarized the current evidence to determine a possible genotype–phenotype association among NS individuals. Twenty-four articles comprising of 84 NS (including 9 patients with a severe form of NS [Rodriguez syndrome]) patients were examined, of which 76% were caused by variants in SF3B4 (OMIM *605593, Splicing Factor 3B, Subunit 4). Within the SF3B4 gene, variants located in exon 3 commonly occurred (20%) from a total identified variant, while hotspot location was identified in exon 1 (12%), and primarily occurred as frameshift variants (64%). Thirty-five distinct pathogenic variants within SF3B4 gene were identified with two common sites, c.1A > G and c.1060dupC in exons 1 and 5, respectively. Although no significant genotype–phenotype association was found, it is notable that patients with frameshift SF3B4 variants and predicted to lead to nonsense-mediated RNA decay (NMD) of the transcripts tended to have a more severe clinical manifestation. Additionally, patients harboring variants in exons 2 and 3 displayed a higher proportion of cardiac malformations. Taken together, this article summarizes the pathogenic variants observed in SF3B4 and provides a possible genotype–phenotype relationship in this disease.
Facilitating International Research on Career Indecision: Developing Career Indecision Profile-Short-5 in China and the U.S.
Authors: Xu Hui , He Runqiu
Published: March 2022

While five-factor model of career indecision proposes five cross-culturally important indecision factors, a psychologically sound brief measure of career indecision that corresponds to the five-factor model is lacking. Thus, using a Chinese college sample ( n = 588) and an U.S. college sample ( n = 762), this study developed and validated the Career Indecision Profile-Short-5 factor (CIP-Short-5) in China and the U.S. Applying item response theory, the CIP-Short-5 consists of five items each for the five overarching domains of career indecision. It showed desirable option occurrence patterns and minimal gender-oriented differential item functioning in both China and the U.S. Additionally, the scale supported the five-factor model over an alternative, four-factor model of career indecision in both China and the U.S. The convergent and discriminant patterns of the CIP-Short-5 with criteria were largely supported in China and the U.S. Last, the results supported the configural and metric invariance of the CIP-Short-5 but did not fully support the scalar invariance of the CIP-Short-5 across China and the U.S. Together, the results offer psychometric evidence for the CIP-Short-5, which has important implications for research and practice on career indecision in the international context in general and in China in specific.
Surface instabilities of soft dielectric elastomers with implementation of electrode stiffness
Authors: Liguori Pietro , Gei Massimiliano
Published: March 2022

This paper contains a thorough investigation into plane-strain electroelastic surface instabilities of dielectric elastomers. We employ a systematic approach to our investigation, introducing three ways to actuate an elastomer device, namely, actuation by means of (1) attached compliant electrodes, (2) sprayed charges onto the opposite surfaces, and (3) fixed electrodes between which the device “floats” in vacuum and expands transversally. We examine electromechanical instability with particular attention to the third listed mode of actuation and the features of the specimen. We then tackle surface instability for the three modes, showing the relationship between applied pre-stress and the stability domain, as well as the characteristics of the obtained bifurcation fields. The effects of the stiffness of the electrode (relevant in the first listed mode of actuation) on surface instabilities are then investigated by adopting an elastic surface–substrate interaction model in which the properties of the coating enter the boundary conditions for the substrate. Various electrode materials are assumed, demonstrating that their implementation in the model increases the number of solutions at bifurcation and changes the overall stability domain. We present this new enriched bifurcation map, showing the dependence on the wavenumber, and characterise the solutions by examining the bifurcated fields.
Sponsorship Disclosure of Influencers – A Curse or a Blessing?
Authors: Giuffredi-Kähr Andrea , Petrova Alisa , Malär Lucia
Published: March 2022

Influencer marketing has become increasingly important in the field of marketing communication as an effective way to reach the appropriate target group. Using their own social media channels, influencers often give the impression that they have a personal rather than a commercial relationship with the brand and the products they promote. Therefore, when influencers post sponsored content, consumers often experience difficulty making accurate distinctions as to whether the influencer is offering a personal recommendation or doing a promotion. Given this issue, we examine to what extent sponsored posts of different influencer types affect consumers’ evaluations of the sponsoring brand and the influencer as well as what role the sponsorship disclosure plays therein. Across four experimental studies, we demonstrate that sponsored posts of mega influencers increase consumers’ persuasion knowledge relative to the posts of nano influencers, which decreases the trustworthiness of those posts and in turn negatively impact both brand and influencer evaluations. Interestingly, our results reveal that this indirect effect is only present when the sponsorship is not disclosed. Thus, more transparency by disclosing such sponsorship can eliminate the negative impacts of persuasion knowledge on the trustworthiness of posts and subsequent evaluations of the brand and the influencer. These findings have important implications for marketing practice and research.
Paradoxes of Social Support in Virtual Support Communities: A Mixed-Method Inquiry of the Social Dynamics in Health and Wellness Facebook Groups
Authors: Babić Rosario Ana , Russell Cristel Antonia , Shanahan Doreen Ellen
Published: March 2022

From parenting to health and wellness, the number of virtual support communities (VSCs) keeps growing. The interactive marketing discipline has primarily documented the positive social dynamics of VSCs: communities provide informational and socio-emotional support that helps members achieve their goals. Yet evidence is mounting that VSCs also exhibit judgment and pressure that ultimately hurt community relationships and engagement. We adopted a mixed-methods approach: a qualitative phase, comprised of netnography and interviews, to explore members’ experiences of a VSC and its complex social dynamics, followed by a quantitative phase to test the emerging model with cross-sectional survey data collected from members of a large number of health- and wellness-related VSCs. The two studies provide empirical evidence of many paradoxical social dynamics of VSCs and their relational and engagement consequences. We find that positive group perceptions can generate the social empathy that ensures the group's informational value is helpful to members’ goals; however, we also find that negative group perceptions create social pressure that can be helpful to relational and engagement outcomes if it increases social empathy but can also be detrimental if it turns into angst. Our findings contribute to research on VSCs, inform interactive marketing practices, and suggest further research opportunities on the social dynamics of VSCs.
Sponsored Influencer Vlogs and Young Viewers: When Sponsorship Disclosure Does not Enhance Advertising Literacy, and Parental Mediation Backfires
Authors: Harms Bianca , Hoekstra Janny C. , Bijmolt Tammo H. A.
Published: March 2022

Using unique data from 609 parent–daughter (8–16 years of age) dyads, in an online experiment we studied two pivotal antecedents of young viewers’ cognitive advertising literacy: influencer-generated sponsorship disclosure (written and/or spoken) and parental mediation style (active or restrictive). A between-subjects, single-factor design was applied with three experimental conditions: written disclosure, spoken disclosure, and both written and spoken disclosure, and a control condition—no disclosure. Variance-based partial least squares structural equation modeling in Smart-PLS 3.0 shows that policy makers’ and parental measures to safeguard young consumers from negative consequences of sponsored vlogs can lead to unanticipated effects. While the combination of written and spoken sponsorship disclosure information as well as an active parental mediation style increase cognitive advertising literacy, restrictive parental mediation negatively affects cognitive advertising literacy. In addition, cognitive advertising literacy negatively affects young viewers’ evaluation of the vlogger and positively affects the attitude toward the sponsored brand. Our findings provide important insights for parents, practitioners, and regulators and contribute to the discussion of how to make influencer marketing more effective and ethical.
In silico Prediction on the PI3K/AKT/mTOR Pathway of the Antiproliferative Effect of O. joconostle in Breast Cancer Models
Authors: Ortiz-González Alejandra , González-Pérez Pedro Pablo , Cárdenas-García Maura , Hernández-Linares María Guadalupe
Published: March 2022

The search for new cancer treatments from traditional medicine involves developing studies to understand at the molecular level different cell signaling pathways involved in cancer development. In this work, we present a model of the PI3K/Akt/mTOR pathway, which plays a key role in cell cycle regulation and is related to cell survival, proliferation, and growth in cancer, as well as resistance to antitumor therapies, so finding drugs that act on this pathway is ideal to propose a new adjuvant treatment. The aim of this work was to model, simulate and predict in silico using the Big Data-Cellulat platform the possible targets in the PI3K/Akt/mTOR pathway on which the Opuntia joconostle extract acts, as well as to indicate the concentration range to be used to find the mean lethal dose in in vitro experiments on breast cancer cells. The in silico results show that, in a cancer cell, the activation of JAK and STAT, as well as PI3K and Akt is related to the effect of cell proliferation, angiogenesis, and inhibition of apoptosis, and that the extract of O. joconostle has an antiproliferative effect on breast cancer cells by inhibiting cell proliferation, regulating the cell cycle and inhibiting apoptosis through this signaling pathway . In vitro it was demonstrated that the extract shows an antiproliferative effect, causing the arrest of cells in the G2/M phase of the cell cycle. Therefore, it is concluded that the use of in silico tools is a valuable method to perform virtual experiments and discover new treatments. The use of this type of model supports in vitro experimentation, reducing the costs and number of experiments in the real laboratory.
Synergistic Effect of Quercetin Magnetite Nanoparticles and Targeted Radiotherapy in Treatment of Breast Cancer
Authors: Askar Mostafa A , El-Nashar Heba AS , Al-Azzawi Mahmood A , Rahman Sahar S Abdel , Elshawi Omama E
Published: March 2022

Quercetin is a potent cancer therapeutic agent present in fruits and vegetables. The pharmaceutical uses of quercetin are limited due to many problems associated with low solubility, bioavailability, permeability, and instability. In addition, the high doses of quercetin show toxic effects in clinical and experimental studies. Therefore, a new strategy is warranted to overcome these problems without the use of toxic doses. The iron oxide nanoparticles can be used as a drug delivery system. This study aimed to prepare quercetin-conjugated magnetite nanoparticles (QMNPs) using biological simple nanoprecipitation and mediated by fungus Aspergillus oryzae. Also, we initiated in vitro and in vivo studies to determine whether QMNPs might sensitize breast cancer to radiotherapy treatment. The structural, morphological, and magnetic properties of the prepared nanoparticles were studied. The results indicated that QMNPs were spherical in shape and 40 nm in diameter. The in vitro studies showed that the incubation of MCF-7, HePG-2, and A459 cancer cells with QMNPs for 24 h effectively inhibited the growth of cancer cell lines in a concentration-dependent manner with IC50 values of 11, 77.5, and104 nmol/mL, respectively. The combination of QMNPs with irradiation (IR) potently blocked MCF-7 cancer cell proliferation and showed significant changes in the morphology of these cells as observed by bright-field inverted light microscopy. Focusing on the long-term toxicity of QMNPs (20 ml/kg), the assessment of hematological, hepatic, and renal markers indicated no toxic effect. Besides, QMNPs inhibited tumor growth and potently enhanced the lateral radiotherapy treatment in N-methyl-N-nitrosourea (MNU)-induced breast cancer in female white albino rats. These anticancer and radiosensitizing activities were ascribed to cytotoxicity, cell cycle arrest, immunomodulation, and efficiency through induction of apoptosis. In a conclusion, these observations suggest that the QMNPs combined with LRT could act as a potential targeted therapy in breast cancer.
Outcomes of telemedicine care during the COVID-19 pandemic: Experience from an intervention program designed for vulnerable population in Brazil
Authors: Carneiro Ana Carolina , de Pinho Guilherme S , Belo José Victor , Bolonhini Sabine , Carneiro Neto Manuel B , Mallet Toueg Adriana , Fernandes Arthur Gustavo
Published: March 2022

Purpose

Telehealth plays an important role on the combat of COVID-19. In this context, the SAS Brasil telemedicine program became a viable option in Brazil, where the population faced challenging access to healthcare services during the pandemics. In this study, we describe the sociodemographic profile, reasons for enrollment, outcomes of consultation, and satisfaction of participants who received telemedicine consultations through the SAS program.

Methods

A retrospective cross-sectional study was conducted with data from the SAS Telemedicine program including consultations performed from July 15, 2020, to April 15, 2021. The study describes the SAS Brasil experience and data collected in the period. Patients’ satisfaction perception was evaluated through the Net Promoter Score (NPS).

Results

A total of 6490 participants were evaluated, 69.5% of them were female and 40.8% with age from 21 to 40 years. In the period, 22,664 teleconsultations were performed, mainly due to Mental health (40.4%), Respiratory (35.8%), and Nutritional (4.5%) disorders. Out of the 6312 patients with a defined outcome along the period, 96.0% were discharged and 4.0% were referred to presential care. The calculated NPS was + 95.77 and most patients answered that they would use the service again if needed (99.21%) and had their issue resolved (89.76%).

Conclusion

During the period of the COVID-19 pandemic, telehealth has been consolidated as a tool that offers access to specialized healthcare with wide acceptance by users and can be implemented in populations in vulnerability situations.
Connecting over the internet: Establishing the therapeutic alliance in an internet-based treatment for depressed adolescents
Authors: Mortimer Rose , Somerville Matthew P. , Mechler Jakob , Lindqvist Karin , Leibovich Liat , Guerrero-Tates Brenda , Edbrooke-Childs Julian , Martin Peter , Midgley Nick
Published: March 2022

Internet-based treatments have been developed for youth mental health difficulties, with promising results. However, little is known about the features of therapeutic alliance, and how it is established and maintained, in text-based interactions between adolescents and therapists in internet-based treatments. This study uses data collected during a pilot evaluation of a psychodynamic internet-based therapy for depressed adolescents. The adolescents had instant-messaging chats with their therapists once a week, over 10 weeks. The adolescents also rated the therapeutic alliance each week, using the Session Alliance Inventory. The present study uses qualitative methods to analyse transcripts of text-based communication between the young people and their therapists. The aim is to identify and describe the key features of therapeutic alliance, and reflect upon the implications for theory and clinical practice. Analysis identified three ‘values’ that may underpin a strong therapeutic alliance: togetherness, agency and hope. A number of therapist techniques were also found, which seemed to create a sense of these values during text-chat sessions. These findings are discussed, alongside implications for future research.
Making a home in the world: Clothes as mnemonic devices through which refugees experience home in flight and resettlement
Authors: Schneider Charlot
Published: March 2022

How do refugees experience home not just in the country of settlement but also along their journeys of flight? Departing from theories that see home as something which is left behind in displacement, this paper explores how clothes act as important mnemonic devices, storing and archiving memories from different times and places, whilst connecting people to new places en route. Through the in-depth analysis of two refugees’ stories, this paper highlights that home is not a onetime accomplishment but a lived experience that people are continuously involved in, especially in times of upheaval and transformation as they search for a safer place to be in the world. Clothes, as one of the few materials that refugees carry, become central to this lived experience not only as semiotic devices, carrying different narratives of home, but also as sensual materials through which different sensations of home are carried, transformed, and negotiated.
The Cultural Formulation Interview—Generating distance or alliance? A qualitative study of practice changes in Danish mental healthcare
Authors: Lindberg Laura Glahder , Carlsson Jessica , Kristiansen Maria , Skammeritz Signe , Johansen Katrine Schepelern
Published: March 2022

This article presents provider experiences with the Cultural Formulation Interview (CFI) in Danish mental healthcare for migrant patients. Semi-structured interviews with 17 providers and 20 recorded CFI sessions were analyzed with a constructivist grounded theory approach. Based on our empirical material, we endorse the CFI’s ability to facilitate working alliance and a profound and contextually situated understanding of the patient. Further, the CFI supported less-experienced providers in investigating cultural issues. Conversely, we found that CFI questions about cultural identity and background evoked notions of distance and ‘othering’ in the encounter. Nine providers had felt discomfort and professional insecurity when the CFI compelled them to introduce explanatory frameworks of culture in the mental health assessment. Eleven providers had experienced that the abstract nature of the questions inhibited patient responses or led to short and stereotypical descriptions, which had limited analytical value. We describe the contradictory CFI experiences of alliance versus distance at three levels: 1) at the CFI instrument level; 2) at the organizational level; and 3) at the contextual and structural level. We demonstrate benefits and pitfalls of using the CFI with migrants in Denmark, which is an example of a European healthcare context where cultural consultation is not an integrated concept in health education programs and where the notion of culture is contentious due to negative political rhetoric on multiculturalism.

We suggest that the CFI should be introduced with thorough training; focus on fidelity; and supervision in the clinical application and understanding of the concept of culture.
Diagnostic accuracy of clinical indicators of Imbalanced nutrition in pediatric patients submitted to chemotherapy
Authors: Carvalho Priscilla Magalhães de Oliveira , Lopes Marcos Venícios de Oliveira , Teixeira Iane Ximenes , Nunes Marília Mendes , Diniz Camila Maciel , da Silva Viviane Martins , de Menezes Angélica Paixão
Published: March 2022

To analyze the accuracy of clinical indicators of nursing diagnosis, Imbalanced nutrition: less than the body requirements in pediatric patients undergoing chemotherapy. A cross-sectional study was carried out in a pediatric oncohematology unit. A total of 123 children aged 5–18 years were evaluated. The Standards for Reporting Diagnostic Accuracy Studies (STARD) protocol was used. Latent class analysis was performed to obtain sensitivity and specificity of clinical indicators. The diagnosis was identified in six children (5.23%). The most frequent clinical indicator in the study was report of food intake less than recommended daily allowance ( n = 61; 49.6%), followed by excessive hair loss ( n = 49; 39.8%), misperception ( n = 42; 34.1%), satiety immediately upon ingesting food ( n = 32; 26%), lack of information ( n = 30; 24.4%), and pale mucous membranes ( n = 22; 17.9%). The 10 indicators that sensitivity and specificity were statistically superior to 50% were food intake less than recommended daily allowance, misperception, insufficient interest in food, lack of food, hyperactive bowel sounds, body weight 20% or more below ideal weight range, insufficient muscle tone, food aversion, abdominal cramping, and misinformation. The clinical indicators Food intake less than recommended daily allowance and Misperception can be considered the most important indicators for the initial inference of the diagnosis due to their high values of specificity and sensitivity. It is essential that nurses provide targeted and qualified assistance based on the signs and symptoms presented by patients, as they will be able to design appropriate interventions to obtain the desired results.
Experimental and numerical study on mechanical behavior of high-strength lockbolted friction grip connections
Authors: Lei Ming , Zheng Kaifeng , Zhu Jin , Heng Junlin , Feng Xiaoyang , Wang Yawei
Published: March 2022

Despite the wide application of high-strength bolts joint in steel bridges, there are still some issues with this jointing technology such as large variation in the bolt preload, looseness of the joint as well as the fatigue problem. In this study, the high-strength lockbolted friction grip (HSLFG) connections were proposed as an alternative and the experimental results indicated that HSLFG connections have comparable mechanical behavior and strength to that of high-strength bolted friction grip (HSBFG) connections. First, the experiments were carried out on four HSLFG connections and four conventional HSBFG connections, in which the mechanical properties of both connections such as the failure modes, load-bearing behavior, and load-strain relationships were obtained and compared. The experimentally results indicate that the preload of the high-strength lockbolts satisfy the requirements of Eurocode3 and JTG D64-2015. Refined finite element (FE) models were established and were verified against the experimental results which proved the FE models could effectively predict the elastic-plastic behavior and positions of rupture of the HSLFG connections. Furthermore, the parametric analysis of FE model was conducted to investigate the effect of element types, friction coefficients on the mechanical property of the HSLFG connections. This research provided a promising strategy for the development requirements of HSLFG connections in steel bridges.
Triaxial strength and failure criterion of ultra-high performance concrete
Authors: Wu Pengtao , Wu Chengqing , Liu Zhongxian , Xu Shenchun , Li Jun , Li Jie
Published: March 2022

Over the past few decades, ultra-high performance concrete (UHPC) has been widely studied and applied because of its outstanding mechanical properties. A large number of studies have been conducted on the uniaxial static and dynamic performance of UHPC materials, however, limited investigations exist on the triaxial compression properties of UHPC. In this study, 98 cylindrical samples of UHPC with different steel fiber volumetric ratios (0.0%–1.5%) were tested to investigate the triaxial behavior of UHPC under different confining pressures (0 MPa–40 MPa). The confining pressure and steel fiber contents have clear impact on the triaxial strength, failure mode, crack width, and the angle between the oblique crack and the axial direction. The triaxial compressive strength and compressive toughness of UHPC subjected to various confining pressures are obtained from the tests and discussed in the study. Based on the testing data, the triaxial compression failure criterion of UHPC is established according to the unified strength theory. Finally, the simplified empirical equations for the full stress-strain curves of UHPC specimens subjected to uniaxial and multiaxial loads are derived, and good agreement with the experimental results is achieved.
Recent progress in buckling restrained braces: A review on material development and selection
Authors: Zhuge Yan , Ma Xing , Zeng Junjie
Published: March 2022

Passive energy dissipation devices are a widely accepted solution used to improve the response of the structures under seismic conditions. While several types of passive energy dissipation elements have been proposed for replaceable elements, buckling restrained braces (BRB) was one of the most effective replaceable elements which has been used to retrofit frame structures in the past few years. A traditional BRB consists of a steel brace core with a cruciform cross section that is surrounded by a stiff steel tube (restraining unit) and unbonded materials to ensure the brace to move freely. The region between the tube and brace is filled with concrete-like materials. In recent years, a significant amount of research has been carried out on new types of BRBs which are more efficient and inexpensive. This paper presents an overview of recent advances in the development of BRB materials and buckling mechanism, with an emphasis on the material development for the restraining unit. The application of fibre-reinforced polymer (FRP) as restraining unit in BRB is highlighted.
Buying the news: A quantitative study of the effects of corporate acquisition on local news
Authors: LeBrun Benjamin , Todd Kaitlyn , Piper Andrew
Published: March 2022

Local newspapers are increasingly subject to predatory corporate acquisition—corporate takeovers in which media conglomerates purchase publications in financially precarious states, drastically cut staff, and in certain cases consolidate newsroom operations. We investigate how this practice alters the information environment of 31 corporate-owned local newspapers across over 130,000 articles. Formalizing local information across three dimensions, we find (a) that corporate acquisition is associated with a reduction in the volume of local content produced, (b) that the coverage of local places following acquisition is significantly more concentrated than prior to acquisition, and (c) that articles produced to be shared across regional hubs of corporate-owned publications are significantly less local—and discursively more national—than articles produced for a single local market. Our findings identify reductions in newsroom resources and regional hubs of publications as detrimental to the information environment of local communities.
Platformed antisemitism on Twitter: Anti-Jewish rhetoric in political discourse surrounding the 2018 US midterm election
Authors: Riedl Martin J. , Joseff Katie , Soorholtz Stu , Woolley Samuel
Published: March 2022

What does antisemitism look like in the context of political discussions on Twitter? In this article, we introduce the notion of platformed antisemitism. We first define it as a platform-agnostic concept, and then explore it through an exemplary case study of Twitter and its affordances by way of a mixed-methods analysis of discourse surrounding the 2018 US midterm election. Via qualitative textual analysis, we document how political discourse on Twitter is marred by antisemitic conspiracy theories that intersect with QAnon and Trump/MAGA support. Through quantitative content analysis of a sample of 99,062 tweets, we highlight a list of terms and hashtags most often associated with antisemitic speech on Twitter and showcase how specific affordances on the platform (quote-tweets, hashtags) amplify and/or diminutize antisemitic speech. Via Lasso regression, we introduce an antisemitism classifier that can be used to further refine future detection efforts of antisemitic speech.
Factors that contribute to strong working alliances between case managers and clients
Authors: Cheng Tyrone C , Lo Celia C
Published: March 2022

Published literature has demonstrated that strong case manager–client working alliances foster improvement among clients. Reflecting a case-management context, this study explored how working alliances, as perceived by clients, are related to interpersonal capacities (or social support); intrapersonal dynamics; severity of problems facing client; and other client and case manager characteristics. The study included 101 clients and their 26 case managers at four nonprofit social-service agencies.

Findings

Working alliances, as perceived by clients, were observed to be associated positively with 3 variables: working alliance as viewed by case manager, length of time client worked with case manager, and client female gender. In turn, client mental-health or substance-use problem was linked to client unfavorable perception of working alliance. No link was observed between client perception of alliance and 6 variables: client social support, goal achievement, problem severity, client–case manager shared ethnicity, case manager work experience, and client age.

Applications

The findings suggest that working alliance is collaborative and interactive throughout the helping process. This impacts social work training protocols. Case managers who must establish working alliances with clients need the relevant collaboration skills, which may need to be introduced and practiced at in-service meetings or workshops.
Toward a more in-depth measurement of cultural distance: A re-evaluation of the underlying assumptions
Authors: Correa da Cunha Henrique , Farrell Carlyle , Andersson Svante , Amal Mohamed , Floriani Dinora E
Published: March 2022

Some 20 years ago, Shenkar (2001) criticized several of the underlying assumptions of the cultural distance (CD) construct. Despite this, researchers continue to use the same metric which fails to address many of the underlying problems. As a result, CD studies seem to generate results which are often contradictory. Rather than rejecting the distance metaphor, the main objective of this study is to provide a more in-depth measure of CD that addresses the assumptions of linearity, symmetry, equivalence, and discordance. We propose that, while the size of the cultural distance between home and host countries may be relevant for some dimensions, it is incomplete, as it does not account for the distinct characteristics of the cultural dimensions, the direction toward countries with different profiles and the contextual settings of the study. We test our hypotheses on a sample from the Orbis database consisting of foreign subsidiary firms from Latin America, other emerging markets from outside the region, and from developed countries operating in 10 of the largest economies in Latin America. Our dataset includes 4226 firm-year observations and a combination of 168 home and host countries. Latin America provides a suitable context for this study, not only because of the diversity of firms from different contexts operating in the region, but also because the region allows us to investigate the influence of home country history and tradition on firms’ ability to conduct business in different cultural contexts. Our assessment of CD shows in a precise manner that size together with direction might be adequate for describing the effects of some dimensions of CD on firm performance, while for other dimensions, it is clearly a matter of country profile. By combining our metric with different national culture frameworks, future studies would be able to complement and strengthen our findings and conclusions.
The Impact of Artificial Intelligence on Expertise Development: Implications for HRD
Authors: Ardichvili Alexandre
Published: March 2022

Problem

The implementation of artificial intelligence (AI) is assumed to lead to increased productivity of knowledge workers. However, AI could also have negative effects on the development of professional expertise.

Solution

A review of the literature on expertise development is provided, followed by examples of AI implementation in a knowledge-intensive profession, accounting. The analysis of these examples suggests that automation can result in the loss of expertise due to reduced opportunities for learning from deliberate practice and experienced colleagues, and from working on progressively more complex tasks. Implications for human resource development (HRD) include creating alternative individual development opportunities and promoting organizational cultures conducive to expertise development in human-machine interaction modes.

Stakeholders

The results of this study will be of interest to scholars of HRD, accounting education, and human-machine interaction. Practical implications will be of relevance to HRD professionals and managers responsible for the implementation of artificial intelligence solutions.
Multiplicatively weighted Voronoi-based sensor collaborative redeployment in software-defined wireless sensor networks
Authors: Wang Minghua , Ou Ran , Wang Yan
Published: March 2022

Large-scale deployment of mobile wireless sensor networks has been widely used in some dangerous and hostile urban security surveillance scenarios. As a new network architecture, software-defined networks was introduced into wireless sensor networks to form a new software-defined wireless sensor networks to solve the problem of balanced large-scale deployment of sensor networks and simplify the complexity of network management. In this article, we first develop an original confident information coverage–based multiplicatively weighted Voronoi diagram through sensor clustering and sensor collaborative sensing. And then, we propose two sensor collaborative redeployment algorithms based on the novel confident information coverage–based multiplicatively weighted Voronoi diagram and software-defined wireless sensor networks architecture to provide high-confidence coverage and improve the coverage ratio. Finally, we demonstrate the superiority of the confident information coverage–based multiplicatively weighted Voronoi diagram and the effectiveness and efficiency of our proposed algorithms via a series of experiments.