bluuebunny/crossref_metadata_2025 huggingface dataset:
Становлення та розвиток жіночої середньої фахової освіти у Західній Україні (кін. ХІХ-поч. ХХ ст.)
Authors: Sivkovych Halyna
Published: January 2019

У статті цілісно проаналізовано ґенезу середньої фахової жіночої освіти на захід-ноукраїнських землях кінця ХІХ – початку ХХ ст., простежено еволюцію середнього жіночого професійного шкільництва в регіоні, встановлено основні періоди й тенденції у його розвитку. На основі ґрунтовного аналізу наукової літератури минулого та сучасності, шкільних звітів та архівних документів досліджуваного періоду визначено організаційні основи заснування та функціонування жіночих навчально-виховних закладів з підготовки вчителів. Розкрито роль державного і громадського чинників, релігійних організацій та окремих педагогічних постатей у становленні жіночих учительських семінарій Східної Галичини, Північної Буковини і Закарпаття. Встановлено, що через що через дискриміна¬ційний характер офіційної освітньої політики в усіх адміністративних краях австрійської держави, де переважало українське населення, кількість учениць-українок у них була незначною.
Формування культури наукового мовлення майбутніх фахівців інформаційної, бібліотечної та архівної справи у процесі професійної підготовки
Authors: Bilavych Galyna
Published: January 2019

Стаття присвячена практичному аспекту проблеми культури наукової мови, під якою розуміємо досконалий рівень мовнокомунікативної підготовки майбутніх фахівців інформаційної, бібліотечної та архівної справи, що передбачає дотримання нормативності української літературної мови, володіння науковим стилем тощо. З’ясовано зміст поняття “культура наукового мовлення”, визначено особливості реалізації норм сучасної української літературної мови в науковому стилі, звернено увагу на найбільш типові для студентських наукових текстів помилки. Більшість помилок у писемному мовленні студентів зумовлена інтерференційними явищами внаслідок інтенсивного впливу російської мови на українську наукову мову.
Актуальні методологічні підходи до підготовки майбутніх учителів іноземної мови
Authors: Rogulska Oxana
Published: January 2019

В статті обґрунтовано сучасні методологічні підходи до підготовки майбутніх учителів іноземної мови, а саме: системний, компетентісний, аксіологічний, культуро-логічний, діяльністий, комунікативний, центрований на студенті, міждисциплінарний. Оскільки завдання закладів вищої освіти полягають у створенні та впровадженні нових підходів до навчання, застосування яких сприятиме якості підготовки майбутніх учителів іноземної мови до професійної діяльності в умовах Нової української школи, в статті йдеться про необхідність перенесення уваги з процесу навчання на його результат, а відтак про доцільність запровадження актуальних сьогодні методологічних підходів до підготовки майбутніх учителів.
Physical, verbal, and indirect aggression: Gender differences
Authors: Žukauskienė Rita
Published: January 2019

Gender differences regarding aggressive behaviour were investigated in 154 school children three age cohorts: 8-9, 11-12, 13-14-year-olds through peer rating technique DIAS (Lagerspetz, Björkqvist, 1992, Björkqvist, Österman, Kaukiainen, 1992).The principal finding was that girls made greater use of indirect means of aggression, whereas the boys tended to employ direct means of physical and verbal aggression. Indirect aggressive strategies were not fully developed among the 8-9 boys and girls, but they were already prominent among the 11-12 boys and girls, and much more developed among the 13-14 years-old girls.
Parent-Adolescent Agreement About Adolescents’ Suicidal Thoughts
Authors: Jones Jason D. , Boyd Rhonda C. , Calkins Monica E. , Ahmed Annisa , Moore Tyler M. , Barzilay Ran , Benton Tami D. , Gur Raquel E.
Published: January 2019

OBJECTIVES:

To examine agreement between parent and adolescent reports of adolescents’ suicidal thoughts and explore demographic and clinical factors associated with agreement in a large community sample.

METHODS:

Participants included 5137 adolescents 11 to 17 years old (52.1% girls; 43.0% racial minority) and a collateral informant (97.2% parent or stepparent) from the Philadelphia Neurodevelopmental Cohort. Families were recruited from a large pediatric health care network. Adolescents and parents completed a clinical interview that included questions about adolescents’ lifetime suicidal thoughts.

RESULTS:

Agreement was moderate for thoughts of killing self (κ = 0.466) and low for thoughts of death or dying (κ = 0.171). Discrepancies stemmed from both parental unawareness of suicidal thoughts reported by adolescents and adolescent denial of suicidal thoughts reported by parents. Fifty percent of parents were unaware of adolescents’ thoughts of killing themselves, and 75.6% of parents were unaware of adolescents’ recurrent thoughts of death. Forty-eight percent of adolescents denied thoughts of killing themselves, and 67.5% of adolescents denied thoughts of death reported by parents. Several demographic (eg, age) and clinical (eg, treatment history) characteristics were associated with agreement.

CONCLUSIONS:

Early identification and intervention hinge on reliable and valid assessment of suicide risk. The high prevalence of parental unawareness and adolescent denial of suicidal thoughts found in this study suggests that many adolescents at risk for suicide may go undetected. These findings have important clinical implications for pediatric settings, including the need for a multi-informant approach to suicide screening and a personalized approach to assessment based on empirically derived risk factors for unawareness and denial.
Formação docente e protagonismo estudantil de acadêmicos de Medicina: desafios e perspectivas
Authors: Silva Adan Renê Pereira da , Andrade Anne Karina Pereira de , Santos Nilza Oliveira dos
Published: January 2019

A docência no campo médico tem se constituído em desafio para a formação e exigido a reflexão em torno de perspectivas. O objetivo é discutir alguns desses desafios apontados pela literatura, privilegiando o protagonismo estudantil. Para isso, empreendeu-se pesquisa de revisão bibliográfica, focando autores que tratam da temática. Os resultados mostraram que a formação inicial e continuada de professores na área é urgente, principalmente quando se considera a ausência dela, a falta de percepção do aluno como sujeito da aprendizagem e silenciamentos de questões que potencializam a evasão escolar discente, como excesso de cobrança e pouco protagonismo estudantil. Concluiu-se que, por ser o campo da formação de professores incipiente, necessita ser revisitado: o professormédico precisa se perceber mais professor, o que o levará a pensar o campo pedagógico, e menos médico, para relativizar paradigmas de sua própria formação e enxergar o aluno em uma perspectiva biopsicossocial, mais como sujeito e menos como paciente.
Atitudes e crenças dos estudantes portugueses sobre a homossexualidade: implicações para a cidadania e pedagogia universitárias
Authors: Carvalho Cristiana Pereira de , Pinheiro Maria Do Rosário
Published: January 2019

Este estudo teve por objetivo analisar as crenças e atitudes dos/as estudantes do ensino superior português sobre a homossexualidade. Participaram 108 estudantes da Licenciatura em Ciências da Educação da Universidade de Coimbra, os quais responderam ao Inventário de Crenças sobre a Homossexualidade e à Escala de Atitudes face à Homossexualidade – Versão para estudantes do ensino superior. Os resultados obtidos permitiram identificar a existência de crenças disfuncionais sobre a homossexualidade, associando-a erradamente a problemas de identidade e de expressão de gênero, a grupos de risco na transmissão do Vírus da Imunodeficiência Humana/Síndrome da Imunodeficiência Adquirida (HIV/AIDS), a uma escolha individual e a ser resultado da influência de uma família homossexual. Por outro lado, as estudantes apresentam mais atitudes de defesa pelos direitos dos homossexuais, os/as estudantes que se consideram religiosos/as têm atitudes de maior rejeição à proximidade de pessoas homossexuais, os/as estudantes que têm um amigo gay ou uma amiga lésbica ou que falam com os/as amigos/as sobre o tema da orientação sexual apresentam atitudes menos discriminatórias e os/as estudantes mais interessados em ver o tema da orientação sexual debatido na Universidade foram os/as que apresentaram atitudes mais positivas e menos discriminatórias face à homossexualidade. Verificou-se ainda que as crenças funcionais sobre a homossexualidade estão associadas às atitudes positivas face à homossexualidade. Considerando estes resultados, apresentam-se algumas implicações para os currículos na área da cidadania e para as práticas pedagógicas de atenção à diversidade em contexto universitário.
Cybertools of Political Competition and the 2016 American Presidential Campaign
Authors:   Koszalin University of Technology, Górka Marek
Published: January 2019

In the last decade, one can notice the huge interest of researchers in the field of cyberpolicy, which is primarily due to the widespread use of the Internet in the public space. This fact is also an impulse for conducting interdisciplinary research that combines knowledge from social sciences on the one hand, and uses content from technical sciences on the other. Compared to the form of conducting election campaigns in the 20th century in the U.S., during the 2016 election campaign there were significant changes in the conduct of political struggle. These changes consist above all in the use of cybernetic tools, which to a large extent, however difficult to determine, shaped electoral behavior. The contemporary political competition is more and more dependent on technology, which becomes the main element of the professionalization of election campaigns. Investigating the impact of cyberspace on electoral results is a big challenge, considering the fact that the area of cybertechnology is extremely complex. Cyberspace has now become a field for many political phenomena that are constantly evolving and in most cases their importance is immense for the functioning of the political system. The article is intended to deal with selected phenomena related to cybertechnology that were compared with other events from the U.S. election campaign in 2016. The article aims to investigate selected events resulting from the use of cybertechnology, which had an impact on electoral behavior.
Conspiracy Theories Are Not Only for Election Losers. Anti-system Parties and Conspiratorial Distrust in Poland
Authors:   Jagiellonian University, Czech Franciszek
Published: January 2019

Using data from a nationally representative survey in Poland, this study looks at the links between post-election attitudes, ideology and conspiratorial distrust toward public sphere. The reference point is an argument made by Joseph Uscinski and Joseph Parent. They provide evidence that conspiracy theories are more popular among election losers in the United States. Data presented in the article shows a limitation of the argument and the special role of anti-system party in the Polish parliamentary election of 2015. Therefore, the more comprehensive understanding of conspiracy theories within the field of political science is discussed.
The Born Frees as Assertive Citizens? Student Protests and Democratic Prospects in South Africa
Authors:   Bratislava International School of Liberal Arts, Kusá Dagmar
Published: January 2019

Massive student protests in South Africa in the past few years, largest since the times of the anti-apartheid struggles, raised several questions for political scientists. Are we witnessing a generational change? Or are they a sign of a broader global shift towards “assertive citizenship” present in advanced democracies and democratizing countries? To answer these questions, this paper examines the levels of political support and nature of political participation among the young generation. The paper also points out that generational change is not immediately visible in public opinion polls but is a process of a gradual narrative construction. Protests brought with them a challenge to the founding narrative of a united Rainbow Nation and reconciliation with the past, leading to a fracture in democratic stability. For the democratic project to succeed, it is essential that the national project in South Africa does not fall apart.
Reflections on the Proposal to Introduce a Term Limit for Elected Officials Effects and Implications
Authors:   Nicolaus Copernicus University in Toruń, Marszałek-Kawa Joanna
Published: January 2019

The problem of the lack of “generational replacement” in Poland is particularly evident on the local self-government level. For years, there has been an ongoing public debate on the adoption of legal solutions introducing term-limits for the office of commune head, mayor and president of the city. Politicians of Law and Justice returned to their idea from 2005 and, shortly before the local elections of 2018, decided to prepare new regulations in this respect. They argued that the adopted solutions create real prospects for implementing projects by young politicians and activists. However, the issue was hotly debated and the initiators’ motives were put into question. There is no doubt that a two-term limit in local selfgovernment units has always stirred up emotions. A lot of self-government officials perceive it as a regulation which violates the provisions of the Constitution of the RP. The aim of this paper is to present the public debate on the adopted solutions and discuss their assumptions.
Interactions between energy piles caused by temperature
Authors: Wang Zhong-jin , Fang Peng-fei , Wang Kui-hua , Zhang Ri-hong , Li Fu-yuan
Published: January 2019

A new simplified method is proposed to estimate the zero point of displacement variation, assuming that the pile shaft and end resistance are in the elastic stage. The additional pile axial force was calculated by using the proposed method. The temperature distribution among surrounding soils was estimated by using the finite-line-source model. The temperature distribution obtained by the proposed method was compared with that obtained by the finite-element model, and a good agreement was obtained. A method for estimating the interaction caused by heating between energy piles is proposed, and a comparison between the calculated results obtained by the proposed method and those obtained using Abaqus software on energy piles was done to verify the accuracy of the proposed method. It is shown that reasonable predictions about interaction between energy piles can be made without expensive and time-consuming analyses by means of the method proposed in this paper.
Proactive highway traffic control with intelligent multi-objective optimisation algorithm
Authors: Xie Huahui , Tu Lili , Fang Jie , Easa Said M.
Published: January 2019

The great increase in car ownership has led to the daily recurrence of traffic congestion. Thus, traffic mobility, safety and emission concerns have become the most serious challenges for transportation researchers. To mitigate traffic congestion, a variety of proactive traffic-control strategies, such as ramp metering (RM), have been intensively investigated and deployed. With the aim of improving freeway traffic conditions, RM regulates the on-ramp flows dynamically in response to dynamic road conditions. However, most early RM strategies focus on optimising the traffic from one single aspect. This paper presents an RM control algorithm that predicts and evaluates the RM-controlled future traffic states. The impact of RM control was evaluated using a macroscopic traffic-flow model. The designed RM control algorithm possesses a multi-objective optimisation module, which improves the traffic network from the aspects of mobility, safety and emissions. The designed algorithm is evaluated through simulation and calibrated using field data collected over an 11 km major freeway stretch in Edmonton, Alberta, Canada. The comparison of the proposed algorithm-controlled scenario and the uncontrolled scenario shows that the proposed RM control algorithm can effectively relieve traffic congestion, improve safety and reduce carbon emissions concurrently.
Adjunct corticosteroid treatment in patients with pneumonia: A precision medicine approach
Authors: Gavrilovic Srdjan , Andrijevic Ana , Mujakovic Aida , Odeyemi Yewande , Paralija Belma , Gajic Ognjen
Published: January 2019

Pneumonia is the leading infectious cause of death worldwide. While inflammation is critically important in host response to microbial invasion, exaggerated inflammation can damage the lungs, contributing to respiratory failure and mortality. Corticosteroids are effective in reducing inflammation and can also cause immune suppression. Presently, clinicians are unable to reliably distinguish between exaggerated and appropriate immune response and thus cannot rapidly identify patients most likely to benefit from adjunctive corticosteroids. In this review, we propose a biomarker-guided, precision medicine approach to corticosteroid treatment, aimed to give these medications at appropriate dose and time and only to patients who have exaggerated inflammation.
Hyperbranchedpolymer-Rhodamine (HBP-Rh) preparation v1
Authors: kim Il , Choi Changin
Published: January 2019

To create the HBP–Rhodamine (Rh) compound, the HBP was placed in a one-neck flask and vacuum-dried at 60 °C for 2 h to remove any excess moisture. Dimethylformamide (DMF) was then added and dissolved. Rhodamine B was added, and the mixture was stirred for 5 min. The solution was cooled to 0 °C, and N-(3-dimethylaminopropyl) -N'-ethylcarbodiimide hydrochloride (EDC) and dimethylaminopyridine were added. After stirring for about 30 min, it was continually stirred while slowly warming it to room temperature. The solvent was removed using a rotary evaporator and precipitated with excess diethyl ether. The solution was then dissolved in DMF, dialyzed in water for 3 days with a dialysis membrane (molecular weight cutoff = 2 kDa), and then dried under vacuum. HBP-Rh was now ready for use. This synthesis process was presented in Figure 1.
Experimental Protocol (Indigocarmine, HBP-Rh, HBP-RB) v1
Authors: Kim Il , Choi Changin
Published: January 2019

The ex vivo tests were performed within the framework of two trials to evaluate the coloring power and persistence of Hyperbranched-Rhodamine compound (HBP-Rh) and Hyperbranched-Rose Bengal compound (HBP-RB). Indigo carmine dye was used as the control. each HBP–dye compound was injected into the submucosal layer of the stomach and colon of a 40-kg pig (Fig 1). After the injection, the organs were stored in a dark, silent area at 4 °C. Trial 1 Indigo carmine and HBP-Rh were tested during the first trial. The indigo carmine was injected at a single concentration of 8 mg/ml. HBP-Rh was divided into high and low concentrations. High concentrations of HBP-Rh were 10, 5, and 1 mg/ml. Low concentrations were 0.5 and 0.1 mg/ml. These concentrations were injected as 2-ml samples into the gastric submucosal layer and 1.5-ml samples into the colonic submucosal layer. We then observed color changeon the serosal surface immediately after the injection (Day 0) and any changes in its appearance in the serosal surface at post-injection days (PIDs) 1 and 5. Trial 2 Only HBP-RB was used for the second trial. The HBP-RB concentrations injected were 10, 5, and 1 mg/ml, respectively. Similar to Trial 1, each concentration of HBP-RB was injected as 2-ml samples into the gastric submucosal layer and 1.5-ml samples into the colonic submucosal layer. Again, we observed color change on the serosal surface immediately after the injection (Day 0) and on PIDs 1 and 6.
ORTAOKUL ÖĞRENCİLERİNİN FEN BİLİMLERİ DERSİNDE KENDİ KENDİNE ÖĞRENME BECERİLERİNİN YORDANMASINDA KAYGININ ROLÜ
Authors: Kahyaoglu Mustafa , Yetişir Mehmet İkbal , Birel Fırat Kıyas
Published: January 2019

Bu araştırmanın amacı, fen bilimleri eğitiminde önemli bir duyuşsal
değişken olan kaygının ortaokul öğrencilerinin fen bilimleri dersinde kendi
kendine öğrenme becerilerinden olan planlama ve güvenme becerilerini anlamlı
bir şekilde yordayıp yordamadığının incelenmesidir. Bu çalışma çerçevesinde
verilerin 79’u (%40) kız ve 109’u (%60) erkek olmak üzere toplam 188 ortaokul
öğrencisinden elde edilmiştir. Araştırma korelasyon araştırma türlerinden
ilişkisel tarama modelindedir. Araştırmada veri toplama aracı olarak Aydede ve
Kesercioğlu (2009) tarafından geliştirilen Kendi Kendine Öğrenme Becerileri
Ölçeği ile Kağıtçı ve Kurbanoğlu (2013) tarafından geliştirilen Fen ve
Teknoloji Dersine Yönelik Kaygı Ölçeği kullanılmıştır. Araştırmada verilerin
analizinde, bağımsız örneklem grubu t-testi, korelasyon ve regresyon analizi
kullanılmıştır. Araştırmadan elde edilen sonuçlara göre ortaokul öğrencilerinin
fen bilimleri dersinde kendi kendine öğrenmeye yönelik planlama ve güven
becerileri ile kaygı düzeyleri arasında negatif yönde anlamlı bir ilişkinin
olduğu belirlenmiştir. Ayrıca araştırma sonuçları, öğrencilerin kaygılarının
kendi kendine öğrenmeyi planlama ve güvenme becerilerinin anlamlı bir
yordayıcısı olduğunu göstermektedir.
LISTS OF VOCATIONAL EDUCATION PROGRAMMES: STATUS AND POSSIBLE WAYS OF MODERNISATION
Authors: Blinov V. I. , Kurteeva L. N. , Sazonov B. A.
Published: January 2019

Introduction. The liberalisation of state educational standards and the provision of greater autonomy for educational institutions in the formation of educational programmes indicate the need for development of a new classification system for Russian education, which should become common for all types of professional educational programmes, including additional training programmes.

The aim of the publication was to discuss the status and possible ways to modernise the system of classification of educational programmes in Russian vocational education, taking into account the prospects of its development and the constant replenishment of the registers of professional standards and qualifications.

Methodology and research methods. In the course of the study, a retrospective analysis of the development of the classification system of professional educational programmes was used, during which the best Russian and foreign practices were compared.

Results. The features of the current lists of professions and specialties of secondary vocational education and areas of improvement in accordance with modern requirements of the system of classification of professional educational programmes used in these lists were considered. For updated lists, a new composition of enlarged groups of the classification system of vocational education programs has been proposed, coupled with a list of areas of professional activity of the register of professional standards of the Ministry of Labour of Russia.

Scientific novelty. For the first time, it is proposed to refuse classifiers that are strictly tied to the lists of professions, specialties and training areas approved by the Ministry of Education and Science, which formally copy these lists. Combining the classification systems of vocational education programmes and areas of professional activity will allow an adequate comparison of statistical information on training in the education system with their actual use in the labour market.

Practical significance. The introduction of the proposed classification system allows us more fully to take into account data on the training of specialists in the Russian system of vocational education, to reflect this data as accurately as possible in national and international educational statistics and to correlate them with employment indicators in various sectors of the economy and production.
Vector Planning and Corneal Topographic Astigmatism
Authors: Alpins Noel ,   NewVision Clinics, Cheltenham, Victoria, Australia
Published: January 2019

The concept of planning refractive laser treatments using parameters other than manifest or wavefront refraction was somewhat of a novelty until topography-guided treatments came to the forefront more recently. However, both forms of treatment still have their limitations: manifest and wavefront refraction-based treatments do not take into account the effects on corneal astigmatism, and topography-guided treatments do not take into account any astigmatism behind the cornea or any cortical processing involved in the patient’s subjective astigmatic perception. The answer to optimally correcting the astigmatism of the eye is to treat somewhere between the two extremes of refractive cylinder and corneal astigmatism. This can be done using the systematic approach of Vector Planning® (ASSORT Pty. Ltd., Cheltenham, Victoria, Australia). Vector Planning is a systematic approach designed to treat the maximum amount of astigmatism of the eye, while reducing the amount of corneal astigmatism remaining postoperatively compared to treatments based on refractive parameters alone.
Strategic Aspects of Intellectual Property Management in the Fashion Industry
Authors: Khvorostyanaya A. S.
Published: January 2019

Purpose:in the present study, the author aims to analyze the strategic aspects of intellectual activity in the fashion industry and to develop recommendations for the formation of an intellectual property management system in this sector of the economy.

Methods:the study is based on the use of a set of methods of theoretical and economic analysis, including analysis and synthesis, the method of description, the method of formal logic.

Results:to achieve the purpose of the study, the author has solved the following tasks: 1) considered the key objects of intellectual property of the fashion industry, which are of strategic importance for the activities of companies in this field; 2) justified the strategic need for targeted management of intangible assets in the industry; 3) clarified the problem of intellectual property management and proposed recommendations for the formation of an appropriate strategic management system in the fashion industry.

Conclusions and Relevance:it is very important for fashion industry companies to explore their competitive advantages for successful existence in the context of increasing international competition. Competitive advantages for this field of activity are mainly expressed in intangible assets. The main strategic objects of intellectual property of enterprises of the industry are commercial product, brand and technical innovations.

The author analyzes the practices of companies in this sector of the economy in terms of situations involving to the use of objects of their intellectual property. It was revealed that the main strategic priority of managing the intellectual property of an enterprise today is the protection, preservation and development of intangible assets as a strategic resource needed to increase competitiveness, as well as the economic and information security of an enterprise. In this regard, the author proposed a strategic framework for building an intellectual property management system as a specific functional area of the centralized strategic management of the company. The study of the strategic aspects of intangible assets and the formation of the intellectual property management system is of scientific and practical interest for the development of effective strategies for the development of companies in the fashion industry.
Regional development programming
Authors: Komkov N. I. , Lazarev A. A. , Romantsov V. S.
Published: January 2019

Purpose: the purpose of the article is to study the features of regional development in terms of the need to take them into account in the formation of development strategies. The revealed features are the level of development, potential, geographical location, etc. These features are displayed in the strategy of formation of development projects in the region.

Methods: the methodological basis for the formation of prospects for the development of the region is the methodology of program-target management to solve the problems of development of complex hierarchical systems. The main elements of this methodology are the basis for programming development processes in the space "forecast-strategy-program-project".

Results: the results of the study are to determine the stages of programming the sequence of regional development, finding ways and conditions for the transition between the stages and intermediate goals of development, the formation and selection of development projects. To overcome the contradictions in the formation of the composition of the objectives of the development of projects in a hierarchical system: “macro level – the level of regions – the level of municipalities”, the top priority rule is used over the following. There is also the possibility of adding a lower level of own goals and projects, in accordance with the interests of a particular region and municipality. The task of project selection is one of the most important. Its importance lies not only in the required and available financial resources, but also in shaping the structure of the objective function of each region, adequate to the development goals. Fragments of the scheme of programming of development of the Astrakhan region are given.

Conclusions and Relevance: the current external conditions for the development of the domestic economy dictate the need for the full use of domestic resources and the capabilities of the scientific and technological potential to ensure the competitiveness of Russia. This implies a critical attitude towards the development prospects, which are formed without taking into account the national interests of our country. The complexity of strategy formation is due to the hierarchical structure of the country's economy and the difference in interests in the system “macro level – meso level – micro level”. The basis of the proposed approach to development programming is the formation of strategic forecasts. The authors proposed a sequence of actions for programming the formation and selection of development projects at the regional level, as well as a possible list of promising development goals for the region. The analysis of the peculiarities of the development of the regions showed their considerable heterogeneity, which is important to take into account when forming promising strategies. The proposed scheme for the formation of regional development strategies and the mathematical model of project selection are illustrated by the example of one of the municipalities of the Astrakhan region.
Contemporary Condition and Tendencies of the Civil Aviation's Development in Russia
Authors: Kaparulin D. L.
Published: January 2019

Purpose:taking to attention exclusive role of air transport concerning necessity of providing the conditions for normal function of state economy and to satisfy the demands of population, the author put the purpose to analyze the modern condition of the Russian civil aviation development and to propose innovative arrangements in the field of modernization it's material-technical base future development and using.

Methods:the author uses the system approach to perform this research; results of the scientific research of the other specialists in the problem; structure and function analysis; the theory of competitor's struggle for market; complex analyses of statistics and expert evaluations methods.

Results:the system critical analyses of the modern condition of the Russian civil aviation material-technical base development is performed and innovative arrangements in the field of modernization Russian civil aviation material-technical base future development and using are proposed.

Conclusions and Relevance:Russian civil aviation is the single one among all another universal types of transport reached growth of all basic technic-economical indexes for last several years. Due to keeping such positive tendencies and guaranteeing modernization Russian civil aviation material-technical base future development and using on the base of innovative technologies state assistance is necessary in the field of increasing taxes, fuel prices and rent fees for using main productive funds.
Tax Investment Incentives: Worldwide Experience and Russian Practice
Authors: Vyakina I. V.
Published: January 2019

Purpose:the main purpose of the work is research of the applying foreign tax experience to stimulate investment in the Russian business environment, taking into account the special role of the tax system in the national economy, it can be as both a factor in creating threats of the economic security and a resource for its provision. To achieve this goal in the article you must accomplish the following tasks: to perform systematization and critical analysis of theories, empirical research and foreign experience in applying tax incentives to attract investments; to identify the features of the tax relations of the state and business and features of the use of tax incentives in the Russian business environment.

Methods:methods of systematic, logical and comparative analysis of the scientific literature were used, an analysis of descriptive statistics was carried out taking into account the assessment of hierarchical and correlation dependencies between empirical data.

Results:numerous empirical and theoretical studies on the effectiveness of tax incentives as a tool to increase the investment attractiveness of a territory contain extremely contradictory conclusions. The effectiveness of the application of tax benefits differs depending on the conditions of doing business in the jurisdiction. There is no consensus about the effectiveness of tax benefits, the findings of scientists differ depending on the countries and methods. However, despite numerous criticisms, tax incentives remain a popular policy tool for attracting investment in developed, transitional and developing countries.

Conclusions and Relevance:tax relations are essentially multidimensional, complex, and their social, political and legal content is initially conflicting, which determines the need to find a balance between the interests of the state and business. The effectiveness of their practical application to attract investment in the Russian reality is increasing in combination with other non-tax factors, such as business conditions, infrastructure, management quality and institutional environment.
MUSICOTERAPIA E ESTRESSE: ESTUDO DE CASO COM UM CUIDADOR FAMILIAR DE PACIENTE COM INSUFICIÊNCIA RENAL CRÔNICA
Authors: Zanini Cláudia Regina De Oliveira , Alves Helenyce Veloso Sousa , Naghettini Alessandra Vitorino
Published: January 2019

O cuidador de paciente com Insuficiência Renal Crônica (IRC) participa das emoções cotidianas e de fatores estressores que a doença traz consigo. Afetado diretamente com o estresse, pode somatizar doenças que interferem sua qualidade de vida. Esta pesquisa tem como objetivo verificar o efeito da Musicoterapia no estresse e nas estratégias de enfrentamento a partir de um cuidador de pacientes adultos com IRC. Trata-se de um estudo de caso, a partir de um atendimento grupal, com abordagem quali-quantitativa. Os atendimentos aos cuidadores foram realizados na sala de espera no período em que os cuidadores aguardavam os pacientes em sessão de hemodiálise, duas vezes por semana, com duração de 45 a 60 minutos cada intervenção, por seis semanas seguidas, em uma instituição especializada em pacientes renais crônicos. A coleta de dados se deu através de registros audiovisuais, descritivos, relatos verbais e da aplicação do Inventário de Sintomas de Stress para Adultos de Lipp (ISSL), feita por uma psicóloga no momento inicial da coleta de dados e no momento final, após o período de intervenções musicoterapêuticas. Os resultados revelaram que a Musicoterapia possibilitou um canal de comunicação e expressão das emoções do cuidador, além de que facilitou a ressignificação de conteúdos que geravam desconforto. Embora o cuidador não tenha apresentado estresse, foi possível observar o processo musicoterapêutico do mesmo mediante os conteúdos trazidos através do não verbal e do verbal, frente a situações estressoras, além das estratégias de enfrentamento que utilizou durante o período dos atendimentos. Considerou-se que a Musicoterapia pode contribuir para a elaboração de conteúdos que se vinculam ao estresse e acometem os cuidadores de pacientes adultos com IRC, pois auxilia na aquisição de estratégias de enfrentamento de estresse para o seu benefício.
Anatomical Basis for the Optimization of Ultrasound Screening Studies in Perinatology
Authors: Zheleznov L. M. , Levanova O. A. , Nikiforova S. A. , Sarenko S. A.
Published: January 2019

The article discusses the possibilities of expanding the effectiveness of ultrasound screening studies in perinatology based on the results of a study of 894 fetuses. It is established that the standardization of the study is facilitated by one specialist, on the scanner of one model, during a sufficiently short time interval. The range of the regional norm for quantitative intravital parameters of topographic and anatomical parameters of the thymus in the conditions of a large industrial city in healthy pregnant females has been determined and their dynamic changes – absolute growth and growth intensity at the screening inspection stages have been studied. For the first time to describe the quantitative topography of the thymus in fetuses, the shortest distances from the center of the vertebral body and also to the center of the ascending aorta, the pulmonary trunk and the superior vena cava, the thymic-thoracic index were studied, and the dynamics of their growth were traced. For the first time quantitative criteria and dynamic features of the change (biparietal, fronto-occipital dimensions and head circumference, abdominal circumference, femur length, thymus size) in fetuses of HIV-infected pregnant women were determined. For the first time, the fetometric parameters of the bearing fruit in low-, medium- and high-growth pregnant brachy-, meso- and dolichomorphic somatotypes at the stages of the second and third ultrasonic screening. Correlation relationships of fetometry indicators with anthropometric parameters in low-, medium- and tall pregnant brachy-, mezo- and dolichomorphic somatotypes at the stages of the second and third ultrasonic screening survey are shown. The possibilities of morphometric analysis, wide study not only of anatomy, but also of the topography of organs, the application of the laws of teachings on age anatomy, individual anatomical variability, and clinical anthropology are shown on the example of thymus research, features of fetuses of HIV-infected pregnant women, fetuses of women of different constitution and growth.
Influence of Bacteriophage Infections of Microbiota on the Expression of alpha-synuclein in the Rat Intestinal Wall
Authors: Sergeev V. G. , Tanaeva M. S. , Sergeeva T. N. , Chuchkov V. M.
Published: January 2019

The aim of the study was to identify the effect of bacteriophage microbiota infection on the expression of alpha-synuclein (A-syn) in rat small intestinal wall cells.

Material and methods. The work was performed on Wistar rats, which once a day rectally injected a cocktail of bacteriophages against pathogenic bacteria or sterile saline (control). Various parts of the small intestine were frozen on dry ice, and cryostat sections were prepared to immunohistochemically investigation the localization of A-syn in the cells of the intestinal wall after 10 days of experiment.

Results. A significant quantitative increase of immunopositive to A-syn lymphocytes and an increase in the expression of this protein in the neurons of the intermuscular and submucous nerve plexuses were detected.

Conclusion. Bacteriophage infection of the microbiota has a pronounced effect on the expression of alpha synuclein in lymphocytes and neurons localized in the wall of the small intestine.
Changes in thickness of cortex and its layers in the posterior lobe of the cerebellum in postnatal ontogenesis
Authors: Tsekhmistrenko T. A. , Klochkova S. V. , Mazloev A. B. , Nikityuk D. B. , Obukhov D. K.
Published: January 2019

Objective– the study of age-related changes in the thickness of the cortex and its layers in the posterior lobe of the cerebellum of children.

Material and methods.The work is performed on postmortem material (62 cerebellum), obtained from children aged from birth to 12 years who died as a result of injuries without brain damage. Using computer morphometry on the painted method Nissle frontal histological sections of cortex, taken in region right and left posterior quadrangular lobules (H VI) on top of the folia of cerebellum, was measured the cortical thickness and the thickness of molecular and granular layers. Analysis of quantitative data was performed at annual intervals.

Results. The posterior lobe of the cerebellum the increase in the thickness of the cortex in the left hemisphere occurs in two stages: from birth to 1 year and then to 2 years, in the right hemisphere in three stages: from birth to 1 year, and 2 and 7 years. Right-sided asymmetry of the thickness of the cerebellar cortex observed in infants and children 7 years of age, thickness of granular layer in infants and children 9 years. Left-hand asymmetry is specific to cortical thickness and its molecular layer in children 12 months.

Conclusion. The thickness of the cerebellar cortex and its layers in the area of the lobule H VI increases during early childhood, and in the right hemisphere also during the first childhood. Reducing the diameter of the cortex and layer in the posterior lobe of the cerebellum of children from birth to 12 years of age are not detected.
The Effect of a Training Program Based on the PRECEDE-PROCEED Model on Lifestyle of Adolescents with Beta-Thalassemia: A Randomized Controlled Clinical Trial
Authors: Bazpour Malihe , Gheibizadeh Mahin , Saki Malehi Amal , Keikhaei Bijan
Published: January 2019

Background: Lifestyle is a key issue in the concept of health promotion. Lifestyle includes all activities that encourage optimum physical, spiritual, and mental functions. The aim of this study was to determine the effect of a training program based on PRECEDE-PROCEED Model on lifestyle of adolescents with beta thalassemia.
Materials and Methods: In this clinical trial study, 64 adolescents (age 16-20) who referred to the Thalassemia Center of Ahvaz (2015) were selected and randomly divided into two groups: experimental and control group. The components of the PRECEDE-PROCEED Model were used for planning, implementation and evaluation of the program. Changes in predisposing, reinforcing, enabling factors and lifestyle were immediately and a month after the intervention were assessed by a questionnaire based on PRECEDE-PROCEED Model and the Health-Promoting Lifestyle Profile.
Results: The intervention had significantly positive effect on predisposing, enabling and reinforcing factors immediately and a month after the intervention (P < 0.05). Repeated measures analysis of variance showed a significant positive increase in the six dimensions of lifestyle score in the experimental group from baseline to one-month follow-up (P < 0.05).
Conclusion: This study showed that the theory-based training program in adolescents suffered from beta thalassemia disease could improve the adolescent’s awareness and attitude of healthy lifestyle.
Down-Regulation of PU.1 Gene in Pediatric Acute Lymphoblastic Leukemia Patients from South of Iran
Authors: Nakhost Bita , Nasiri Mahboobeh , Karimi Mehran , Montazeri3 Somayeh
Published: January 2019

Background: Acute lymphoblastic leukemia (ALL) is resulted from the infiltration of high amount of non-differentiated cells in bone marrow. Differentiation of the hematopoietic stem cells into specific cell lineage occurs through a highly regulated pathway which is mainly monitored during transcription step. Expression level and pattern of transcription factors e.g. PU.1 determine fate and developmental phases in this pathway. This study was performed to evaluate the expression level of the PU.1 gene in a group of children suffering from ALL.
Materials and Methods: The mRNA expression level of the PU.1 gene was compared between 30 children diagnosed as new cases of ALL and 30 sex- and gender-matched healthy children in the present case-control study. The quantitative real time PCR (qRT-PCR) was used to determine the level of PU.1 gene expression. The data were analyzed using Graph Pad Prism statistical software.
Results: The mRNA level of the PU.1 gene was significantly lower in the blood samples of the ALL patients compared to the controls (p= 0.002).
Conclusion: The results of the study indicated that the PU.1 gene seemed to have key roles in the differentiation pathway of blood cells.
Overexpression of Semaphorin-3A and Semaphorin-4D in the Peripheral Blood from Newly Diagnosed Patients with Chronic Lymphocytic Leukemia
Authors: Parsa Somayeh , Sharifzadeh Sedigheh , Monabati Ahmad , Seyyedi Noorossadat , Ranjbaran Reza , Baghbani Mohammad Reza , Nemati Maryam , Jafarzadeh Abdollah
Published: January 2019

Background: Semaphorins play prominent roles in physiological and pathological processes such as vascular development, tumor growth and immune responses. Semaphorins have different roles in various kinds of cancers, but there is no study concerning their expression in the chronic lymphocytic leukemia (CLL). This study aimed to assess the SEMA3A, SEMA4A and SEMA4D expression in patients with CLL. 
Materials and Methods: Peripheral blood specimens were collected from 30 newly-diagnosed untreated patients with CLL and 30 healthy subjects as a control group. The SEMA3A, SEMA4A and SEMA4D expression was determined by real-time PCR method. 
Results: The fold change expression of SEMA3A and SEMA4D was 7.58 ± 2.66 and 3.20 ± 0.99 in patients with CLL, and was 1.01 ± 0.31 and 1.00 ± 0.27 in healthy subjects, respectively. The CLL patients expressed higher amounts of SEMA3A and SEMA4D in comparison with healthy subjects (P<0.02 and P<0.03, respectively). The fold change expression of SEMA3A in patients with stage II (11.12 ± 5.35) was also higher than patients with stage I (4.49 ± 1.61, P<0.05). No significant difference was also observed in the expression of SEMA4A and SEMA4D between patients with stage I and stage II CLL. In both CLL and control groups, the fold change expression of SEMA3A was higher in men than in women (P<0.03 and P<0.02, respectively).
Conclusion: The results of the study indicated elevated expression of the SEMA3A and SEMA4D in patients with CLL. The SEMA3A expression was influenced by tumor stage and gender of participants.
The Millennials Luxury Brand Engagement on Social Media: A Comparative Study of Brazilians and Italians
Authors: Casagrande Yamawaki Melissa Akemi , Sarfati Gilberto
Published: January 2019

Over the last decades, social media has become one of the most popular online activity among consumers worldwide, leading companies to adapt and evolve their strategies in other to engage the consumer through new medias. Considering the online environment, the social media has a key participation when building consumer brand engagement. Consumers can develop three roles in this situation: consumer, contributor or creator of content. This empirical study aims to understand and compare the consumer brand engagement of millennials in luxury brands on social media between Brazil and Italy. The luxury brands chosen are Louis Vuitton, Chanel, and Prada and the social medias are Facebook, Twitter, YouTube and Instagram. The study used a quantitative research design, with a questionnaire survey. We collected 438 valid answers. The results do not suggest a relationship between culture and consumer brand engagement on luxury brands through social media among millennials from Brazil and Italy. It is possible that cultural differences were not significant in this study because the brands were not able to engage millennial consumers in both countries or because millennials have a low engagement with brands online.