bluuebunny/crossref_metadata_2025 huggingface dataset:
The diagnostic and prognostic values of microRNA-196a in cancer
Authors: Xiong Mengqiu , Wang Ping , Pan Bei , Nie Junjie , Wang Shukui , He Bangshun
Published: December 2020

MicroRNA-196a (miR-196a) was previously reported to be up-regulated in cancers, and it has the diagnostic and prognostic values in cancers. Whereas, the conclusion was still unclear according to the published data. To assess such roles of miR-196a in cancers, the present study was conducted based on published data and online cancer-related databases. To identify the relevant published data, we searched articles in databases and then the relevant data were extracted to evaluate the correlation between miR-196a expression and diagnosis, prognosis for cancer patients. The pooled results showed that miR-196a was a valuable diagnostic biomarker in cancer (area under curve (AUC) = 0.87, 95% CI: 0.84–0.90; sensitivity (SEN) = 0.73, 95% CI: 0.64–0.81; specificity (SPE) = 0.90, 95% CI: 0.81–0.95), which was consistent with the data from databases (breast cancer: miR-196a-3p: AUC = 0.77, 95% CI: 0.74–0.79; miR-196a-5p: AUC = 0.71, 95% CI: 0.66–0.75; pancreatic cancer: miR-196a-3p: AUC = 0.80, 95% CI: 0.73–0.87; miR-196a-5p: AUC = 0.61, 95% CI: 0.51–0.71). In addition, the pooled result revealed that elevated miR-196a expression in tumor tissues (HR = 2.54, 95% CI: 1.79–3.61, PHeterogeneity=0.000, I2 = 75.8%) or serum/plasma (HR = 4.06, 95% CI: 2.67–6.18, PHeterogeneity=0.668, I2 = 0%) of patients was an unfavorable survival biomarker, which was consistent with the data from databases (adrenocortical carcinoma: HR = 5.70; esophageal carcinoma: HR = 1.93; brain lower grade glioma: HR = 2.91; GSE40267: HR = 2.47, 95% CI: 1.2–5.07; TCGA: HR = 1.82, 95% CI: 1.21–2.74; GSE19783: HR = 4.24, 95% CI: 1–18.06). In short, our results demonstrated that miR-196a in tumor tissue or serum/plasma could be used as a prognostic and diagnostic values for cancers.
Integration of diverse DNA substrates by a casposase can be targeted to R-loops in vitro by its fusion to Cas9
Authors: Lau Chun Hang , Bolt Edward L.
Published: December 2020

CRISPR systems build adaptive immunity against mobile genetic elements by DNA capture and integration catalysed by Cas1–Cas2 protein complexes. Recent studies suggested that CRISPR repeats and adaptation module originated from a novel type of DNA transposons called casposons. Casposons encode a Cas1 homologue called casposase that alone integrates into target molecules single and double-stranded DNA containing terminal inverted repeats (TIRs) from casposons. A recent study showed Methanosarcina mazei casposase is able to integrate random DNA oligonucleotides, followed up in this work using Acidoprofundum boonei casposase, from which we also observe promiscuous substrate integration. Here we first show that the substrate flexibility of Acidoprofundum boonei casposase extends to random integration of DNA without TIRs, including integration of a functional gene. We then used this to investigate targeting of the casposase-catalysed DNA integration reactions to specific DNA sites that would allow insertion of defined DNA payloads. Casposase–Cas9 fusions were engineered that were catalytically proficient in vitro and generated RNA-guided DNA integration products from short synthetic DNA or a gene, with or without TIRs. However, DNA integration could still occur unguided due to the competing background activity of the casposase moiety. Expression of Casposase-dCas9 in Escherichia coli cells effectively targeted chromosomal and plasmid lacZ revealed by reduced β-galactosidase activity but DNA integration was not detected. The promiscuous substrate integration properties of casposases make them potential DNA insertion tools. The Casposase–dCas9 fusion protein may serves as a prototype for development in genetic editing for DNA insertion that is independent of homology-directed DNA repair.
The N-terminus ofPaenibacillus larvaeC3larvinA modulates catalytic efficiency
Authors: Turner Madison , Heney Kayla A. , Merrill A. Rod
Published: December 2020

C3larvinA was recently described as a mono-ADP-ribosyltransferase (mART) toxin from the enterobacterial repetitive intergenic consensus (ERIC) III genotype of the agricultural pathogen, Paenibacillus larvae. It was shown to be the full-length, functional version of the previously described C3larvintrunc toxin, due to a 33-residue extension of the N-terminus of the protein. In the present study, a series of deletions and substitutions were made to the N-terminus of C3larvinA to assess the contribution of the α1-helix to toxin structure and function. Catalytic characterization of these variants identified Asp23 and Ala31 residues as supportive to enzymatic function. A third residue, Lys36, was also found to contribute to the catalytic activity of the enzyme. Analysis of the C3larvinA homology model revealed that these three residues were participating in a series of interactions to properly orient both the Q-X-E and S-T-S motifs. Ala31 and Lys36 were found to associate with a structural network of residues previously identified in silico, whereas Asp23 forms novel interactions not previously described. At last, the membrane translocation activity into host target cells of each variant was assessed, highlighting a possible relationship between protein dipole and target cell entry.
Practice Patterns of Speech-Language Pathologists Managing Dysphagia in Dementia: A Cross-Sectional Survey in the United States
Authors: Varindani Desai Rinki , Namasivayam-MacDonald Ashwini
Published: December 2020

Purpose

The purpose of this study was to describe the practice patterns of speech-language pathologists (SLPs) managing dysphagia in persons with dementia (PWD) in the United States. We wanted to investigate if clinicians are (a) adequately prepared to manage dysphagia in PWD, (b) confident in their ability to manage dysphagia in PWD, (c) performing comprehensive dysphagia assessments in PWD, and (d) using evidence-based techniques to manage dysphagia in PWD.

Method

A web-based survey comprising 32 questions was developed, field-tested, and distributed to members of the American Speech-Language-Hearing Association's Special Interest Groups 13 and 15, as well as members of online SLP forums. Two hundred fifty-one responses were obtained and analyzed using descriptive methods.

Results

Respondents were experienced SLPs working primarily in acute care and skilled nursing facility settings. Their confidence in assessment and treatment was found to significantly increase with years of experience (p< .001). The majority indicated more continuing education opportunities need to be offered related to managing dysphagia in PWD. Most reported using assessments that have not been validated for PWD. Clinical swallow examinations were utilized more frequently than instrumental exams to inform treatment planning. There was variability in the treatment techniques used to manage dysphagia in PWD, with a focus on use of compensatory strategies and providing caregiver training. Respondents listed several barriers to managing dysphagia in PWD and stated influences on their clinical decision making.

Conclusions

While some trends emerged regarding dysphagia practice patterns among SLPs managing PWD in the United States, a lack of consensus regarding best practices was apparent. The establishment of formal diagnostic standards, the elucidation of the underlying mechanisms of different types of dementia, and the development of evidence-based treatments for managing dysphagia in PWD could help improve SLP management of dysphagia in dementia and reduce the significant burden of this disease.
A planetary system with two transiting mini-Neptunes near the radius valley transition around the bright M dwarf TOI-776
Authors: Luque R. , Serrano L. M. , Molaverdikhani K. , Nixon M. C. , Livingston J. H. , Guenther E. W. , Pallé E. , Madhusudhan N. , Nowak G. , Korth J. , Cochran W. D. , Hirano T. , Chaturvedi P. , Goffo E. , Albrecht S. , Barragán O. , Briceño C. , Cabrera J. , Charbonneau D. , Cloutier R. , Collins K. A. , Collins K. I. , Colón K. D. , Crossfield I. J. M. , Csizmadia Sz. , Dai F. , Deeg H. J. , Esposito M. , Fridlund M. , Gandolfi D. , Georgieva I. , Glidden A. , Goeke R. F. , Grziwa S. , Hatzes A. P. , Henze C. E. , Howell S. B. , Irwin J. , Jenkins J. M. , Jensen E. L. N. , Kábath P. , Kidwell R. C. , Kielkopf J. F. , Knudstrup E. , Lam K. W. F. , Latham D. W. , Lissauer J. J. , Mann A. W. , Matthews E. C. , Mireles I. , Narita N. , Paegert M. , Persson C. M. , Redfield S. , Ricker G. R. , Rodler F. , Schlieder J. E. , Scott N. J. , Seager S. , Šubjak J. , Tan T. G. , Ting E. B. , Vanderspek R. , Van Eylen V. , Winn J. N. , Ziegler C.
Published: December 2020

We report the discovery and characterization of two transiting planets around the bright M1 V star LP 961-53 (TOI-776,J= 8.5 mag,M= 0.54 ± 0.03M⊙) detected during Sector 10 observations of the Transiting Exoplanet Survey Satellite (TESS). Combining the TESS photometry with HARPS radial velocities, as well as ground-based follow-up transit observations from the MEarth and LCOGT telescopes, for the inner planet, TOI-776 b, we measured a period ofPb= 8.25 d, a radius ofRb= 1.85 ± 0.13R⊕, and a mass ofMb= 4.0 ± 0.9M⊕; and for the outer planet, TOI-776 c, a period ofPc= 15.66 d, a radius ofRc= 2.02 ± 0.14R⊕, and a mass ofMc= 5.3 ± 1.8M⊕. The Doppler data shows one additional signal, with a period of ~34 d, associated with the rotational period of the star. The analysis of fifteen years of ground-based photometric monitoring data and the inspection of different spectral line indicators confirm this assumption. The bulk densities of TOI-776 b and c allow for a wide range of possible interior and atmospheric compositions. However, both planets have retained a significant atmosphere, with slightly different envelope mass fractions. Thanks to their location near the radius gap for M dwarfs, we can start to explore the mechanism(s) responsible for the radius valley emergence around low-mass stars as compared to solar-like stars. While a larger sample of well-characterized planets in this parameter space is still needed to draw firm conclusions, we tentatively estimate that the stellar mass below which thermally-driven mass loss is no longer the main formation pathway for sculpting the radius valley is between 0.63 and 0.54M⊙. Due to the brightness of the star, the TOI-776 system is also an excellent target for theJames WebbSpace Telescope, providing a remarkable laboratory in which to break the degeneracy in planetary interior models and to test formation and evolution theories of small planets around low-mass stars.
A compact platform for efficient generation and single-shot measurement of high-field terahertz wave with a broadband naturally synchronized mid-infrared source
Authors: Ding Yingying , Song Liwei , Qian Junyu , Liu Zhe , Wang Pengfei , Li Yanyan , Peng Yujie , Tian Ye , Leng Yuxin
Published: December 2020

High-field terahertz (THz) wave is a powerful tool for investigating ultrafast dynamics such as the motion of electrons, the vibration of crystal lattices, the precession of spin, etc. In this letter, we demonstrate the generation of intense single-cycle THz pulses from an organic crystal DSTMS (4-N, N-dimethylamino-4'-N'-methyl–stilbazolium 2,4,6–trimethylbenzenesulfonate) via optical rectification. The generated THz field is characterized by single-shot electro-optic sampling with a linearly chirped probe beam. Meanwhile, the spectrum of the infrared pump is broadened to an octave which supports a 1.9-cycle pulse duration. The proposed scheme displays a sophisticated platform of efficient high-field THz generation, single-shot THz measurement, and a broadband mid-infrared source which is naturally synchronized with the THz pulses.
Engineering Education: Key Features of the Digital Transformation
Authors: Aleksandrov Anatolii A. , Tsvetkov Yurii B. , Zhileykin Mikhail M.
Published: December 2020

The paper deals with the digital transformation of engineering education. Such transformation is justified in terms of an engineering education paradigm change. Based on a comprehensive analysis of the didactic system of engineering education, the authors specify the requirements for such important engineering education components as goal setting, content, educational technologies, assessment tools and methods in current educational environment. They provides examples of a practical digital transformation of a number of engineering curricula and syllabi by integrating blended learning based on a Small Private Online Course (SPOC). The authors share their best practices in designing e-learning taking into account the features of the learning-forgetting process, they demonstrate how to make use of the saved time for students’ practical work, how to implement gamification techniques based on such new forms as the Hackathon, Internet of things (IoT) for engineering education. They also provide examples of creating a digital educational environment with specialized software modules to visualize complex mathematical concepts as well as examples of applying principles of artificial intelligence and machine learning to shape a student’s adapted educational trajectory. They discuss how to identify student’s problems with learning material assimilation and suggest a specially developed course including propaedeutic unit for additional study.
A System for Supporting the Adoption of Pedagogical Decisions based on an Assessment of Ownership of Strategies
Authors: Melnikov Yury B. , Ryzhkova Natalia G. , Ivukina Elena S. , Barkov Fedor A.
Published: December 2020

Large-scale changes associated with the digitalization of all industries require from the student to have both knowledge proficiency in the subject field and the formation of critical thinking, the ability to apply and update their knowledge, and the ability to apply knowledge to solve professional problems. Of particular importance in the learning process is the formation of a student’s system of goals, mastery of basic activity strategies. This requires flexible control mechanisms and monitoring to obtain a large amount of information about the current level of potential development of the student. The analysis shows the relevance of developing systems for supporting the adoption of pedagogical decisions in the context of mass education, based on a multi-aspect assessment of the results. The paper describes the author’s theory of adequacy based on the fact that the quality indicator of a model can be obtained by comparing the estimated model with a model accepted as a reference model. The mathematical basis is a clear definition of strategies, their analysis and improvement based on the algebraic approach, the application of which is reflected in the formation of three components: a system of basic elements; systems of standard transformations and standard combinations of elements; an approximation mechanism designed to represent the strategy as the result of applying standard transformations and typical combinations of basic elements. It is substantiated that the results for automated (automatic) decision-making can be obtained on the basis of continuous control and evaluation activities organized according to the developed methodology. The content of the decision-making system is described on the example of a mathematics course.
Skill Oriented Online Master’s Course “Neural Network Modeling of Complex Technical Systems”
Authors: Panfilova Ekaterina V.
Published: December 2020

In this paper we consider the application of online course “Neural Network modeling of Complex Technical Systems” in the Master’s degree programs in the field of nanotechnology and nanoengineering in Bauman Moscow State Technical University. The course has rather practical than theoretical nature. The aim of this course is skill oriented learning. Nowadays neural network models have become a powerful tool of scientific research for engineers and students. The methods studied during the study of the discipline can be applied to estimation, modeling, classification, clustering, forecasting and more. The neural networks modeling plays a significant role in Master’s education and student’s research work. Neural Networks models are successfully presented in graduation theses. Thanks to online educations students can practice at their own pace and study modern neural networks software products, methods of data preparing, designing and training neural network and then apply these algorithms in practice. According to the steps of neural network modeling algorithm the course consists of three main parts and conclusive one. In this paper course structure and study results are presented.
Development of Online-Course “Physical and Chemical Bases of Nanotechnology”
Authors: Sidorova Svetlana V. , Latypov Rodion D.
Published: December 2020

Tendencies of development and introduction of distance education in Russia and the world are considered. The features of online education, including in the direction of training “Nanoengineering” are given. The article shows the necessity of formation of the basic course “Physical and chemical bases of nanotechnology” on the online-platform in the direction of training “Nanoengineering”. The structure of the course is given, the purpose, modules and control measures for checking the residual knowledge of the listener are specified. Presentation of the course “Physical and chemical foundations of nanotechnology” in MS PowerPoint and the availability of video materials makes it easy to integrate the course materials into the distance learning system. The development of the online-course “Physical and chemical foundations of nanotechnology” in the form of a modular structure in the distance education system allows you to embed modules, sections of the course in other disciplines of the specialty. It is proposed to develop a simulation program for practicing practical skills on the topics of the developed online-course.
Logic Artificial Intelligence Application for the Students Individual Trajectories Introduction
Authors: Adamova Larisa E. , Varlamov Oleg O.
Published: December 2020

The individual trajectories and other student learning individualization forms introduction in engineering education are becoming an important competitive university advantage. However, you should be mindful of the choices of learning paths within the framework of requirements of Federal State Educational Standards (FSES): to receive a diploma the student must fulfill all requirements of the FSES. Individualization cannot be arbitrary and must fit within the established framework of the curriculum. Students can study more than the established requirements of the FSES on an individual program. On the other hand, within the established restrictions of the FSES, there are enough alternatives for individualized training to choose the specialization of a certain professional area. For example, for students studying information technology, this specialization can be a choice between different economy sectors: banks, telecommunications, industrial production, logistics, aircraft and rocket engineering, car industry, Internet companies, social networks, etc. If we take developing computer technologies as a basis, then individualization can consist in a more detailed study of one area in IT: databases; expert systems; data security; distributed registries; artificial intelligence (AI); machine learning and image recognition; understanding of natural language; automated systems management and technological processes; robotics, etc. As we can see, opportunities for individualization of training for students exist even within the strict framework of training standards. The paper provides examples of such individualization of training with BMSTU students. Practical work has shown that individualization complicates the work and increases the time spent by university staff on managing trajectories in student learning. The achievements of mivar technologies of logical artificial intelligence allow automating routine operations for managing students’ individual trajectories. In general, artificial intelligence can help in almost all tasks of engineering education in the transition to continuous people training “through life”.
Designing of Mathematical E-courses in the Digital Learning System NOMOTEX
Authors: Dimitrienko Yuriy I. , Gubareva Elena A. , Pichugina Anna E. , Chebakov Dmitriy A. , Tumanov Ivan A.
Published: December 2020

The paper describes a methodology for the design of digital mathematical courses for engineers in the digital learnig system Nomotex (DLS “NOMOTEX”) [1], developed at the Department of Computational Mathematics and Mathematical Physics, Bauman Moscow State Technical University, based on the usage of the Knowledge Base created in the DLS “NOMOTEX”. The technique allows one to create mathematical courses of varying complexity and resulting level of knowledge, depending on the direction of training (specialty).
Blended Learning on Mathematical Analysis in Nomotex Digital Learning System
Authors: Dimitrienko Yury I. , Gordin Michael P. , Gubareva Elena A. , Pichugina Anna E.
Published: December 2020

The paper discusses the methodology and technology of teaching the discipline «Mathematical Analysis» using the new Digital Learning System Nomotex (the Nomotex DLS), developed at the Department of «Computational Mathematics and Mathematical Physics» Bauman Moscow State Technical University (BMSTU). A new conceptual model for conducting lectures and practical classes in blended learning is presented. Examples of interactive computer visualization of some mathematical concepts within the discipline «Mathematical analysis» are presented.
Practical Training Using Simulation and Robotic Kits for Better Future Engineers
Authors: Younes Ali , Alabedeen Ali Zain
Published: December 2020

Every engineering course has two main parts; theoretical and practical. In the last decades, the gap between various engineering institutions has been reduced by using online resources, where all the students and lecturers have access to technological advances in their field. The difficulty arises in the practical part; to gain valuable engineering skills, students need hands-on experience, which means implementing the theoretical part and infer the results of their work. The top-tier institution provides its students with needed equipment and facilities, while many others struggle to fund one plat-form (e.g. universities in small cities and developed regions). To address this problem, we propose using simulation and robotic kits (Lego Mindstorms) in the practical part of courses related to mobile robots, and fuzzy logic. To show that, it is possible to improve the engineering curriculum in the cases of low funds, and improve the quality of future engineering graduates.
Use of Modern Digital Software to Model the Motion Dynamics of Spacecraft during Landing
Authors: Koryanov Vsevolod V. , Heras Maria Hermosilla
Published: December 2020

Landing systems for future space missions in Earth and Mars require trustable technologies capable of achieving their aim in the most accurate way possible. For this purpose, systems should go through rigorous dynamic simulations run by precise and efficient software. This study aims to approximately determine the dynamic motion of a landing vehicle using the modern digital software of Universal Mechanism and MATLAB. Universal Mechanism applies the classic mechanics theory on a model based on the geometry of the spacecraft, taking into account the environmental conditions that affect its motion and the properties of the ground to resist its impact [1]. The forces implied in the vehicle phase of descent are also included in MATLAB code to calculate the landing area of the vehicle according to its re-entry velocity [2-4]. Studies were conducted for different initial conditions and approaches to the surface. As a result, the values of the arising overloads and forces acting on the descent vehicle were obtained [1]. The data provided by the simulations conclude the safest landing options that should be taken into account for the success of future missions.
Mathematical Simulating of the Process of Friction Stir Welding for the Manufacture of Tank Bottoms in Aerospace Construction
Authors: Kruglov Pavel V. , Ponarin Alexey G. , Bolotina Irina A.
Published: December 2020

In modern aerospace technology, one of the perspective ways of assembly parts of thin metal plates is friction stir welding. The advantage of this method is the higher strength of the welds of aluminum alloy joints, compared with the traditional MIG welding for the assembly of rockets and space constructions. However, the lack of friction stir welding is a necessity of formation of the system “machine –tool - part” significantly more effort, which is caused by the need to stir the material in the weld zone in a plastic state. Friction stir welding is used to connect the individual elements of tanks and bodies, in particular, panels, elements of the bottoms with each other. In this paper, is consider the typical design for rocket and space technology bottoms of large tanks. For industrial robot equipped with a special head for friction welding with mixing, a mathematical model of obtaining a spherical bottom from individual segments is proposed. The paper presents a mathematical model describing the geometry of a spherical bottom with a flap articulation and a working zone of an industrial robot, which allows defining constraints on process operation continuous seam welding for standard designs of bottoms and hulls of rocket and space technology. The dependences allowing determining the initial position of the robot relative to the bottom for performing friction stir welding of the continuous seam are proposed.
Simulation Modeling Methods and Tools in the Study of Electronics Preproduction
Authors: Kurnosenko Alexey E. , Levin Ivan V. , Semenyakina Valeria O. , Zakharov Evgeny R. , Sherstyuk Artem E.
Published: December 2020

The paper is devoted to the selection and application of simulation methods and tools when creating a digital model of the production floor and the preproduction of the assembly process of electronic modules on printed circuit boards. The advantage of simulation modeling for creating a digital manufacturing model is shown. The introduction of simulation methods in the educational process is considered. Using the developed digital model for the manufacturing of a typical product as an example, the functional capabilities of the Plant Simulation module from the Tecnomatix software package developed by Siemens PLM Software are considered. The main simulation results in terms of productivity of the designed production floor are considered. The digital model was improved in order to increase the technological equipment utilization rate and the total productivity of the assembly floor.
The Use of UAVs to Save People in the Mountains: Tasks, Problems, Perspective
Authors: Romanova Irina K.
Published: December 2020

The actual problem of organizing and conducting rescue operations in the mountains is considered. The achievements associated with the following factors were noted: the active development of UAVs of various designs, masses, and equipment; development of new information systems, including sensors, communication systems; the emergence of new image processing algorithms and other types of data based on artificial intelligence methods. It was emphasized that a fundamentally new achievement that opens up broad prospects is an integrated approach to the use of rescue equipment, including ground-based mobile equipment, UAVs of various types, global navigation and mobile communications, and professional rescuers. Problems were identified that are associated with the difficulties of the task, including a complex mountainous terrain, snow cover, avalanches, strong winds, low temperatures, immobility and even lack of communication with the victims. The article considers the problem of low temperatures, which leads to icing, which gives rise to an uncontrolled change in the properties of the control object UAVs, difficulties in the functioning of control elements, and distortion of the sensors. Based on the methods of artificial intelligence, including modern methods of detecting damage, a comparative analysis of different approaches was carried out and a predominant approach was drawn, which allows a high degree of certainty to detect problems of UAV icing and timely change of control system settings.
Digital Platform for Distance and On-site Engineering Learning
Authors: Zagidullin Ravil S. , Chernikov Alexander S.
Published: December 2020

This paper considers the experience of elaborating and implementing an on-site and distance practical study of electronics and circuit Engineering in the educational process. Authors provide possibilities of using both distance and on-site laboratory practical works. The paper includes recommendations for choosing hardware-based solutions. It also shows the implemented version of remote user access to individual data of laboratory research, which provides individualization of obtaining experiment data, when using FTP means of data transfer. Data from a remote experiment, in this case, is completely closed from access by third parties, while the teacher is given access to data from experimental studies of all students. The solution was implemented in the LabVIEW platform, as well as the general solution for implementing software access to a remote bench. The paper describes the main elements of the hardware and software system, shows its structure and presents the work examples. It also notes the integration of the LabVIEW software and the Multisim circuit and system simulating platform, which serves to improve the quality of specialists training during distance and on-site practical works. The authors consider several options for conducting distance and on-site laboratory practical works when preparing laboratory layouts for use. The work of students, both distance and on-site, as well as teacher-student interaction, is organized using the MOODLE platform.
The Formation of Students’ Self-Organization Skills in a Technical University
Authors: Kochetova Tatyana N. , Stelmakh Yanina G. , Tihanova Natalia Y.
Published: December 2020

The main components of self-organization and its implementation stages are identified against the background of determining the importance of self-organization skills mastery by technical university graduates for the successful implementation of educational and future professional activities. Based on the social demands generated by the need to form general cultural and professional competencies in the learning process, the necessity to organize students’ independent work in such a way that it motivates self-organization and, as a result, self-education is confirmed. It is proved that the transformation of students’ independent work should be carried out regularly, taking into account the changes taking place in society, using modern information technologies as a kind of organizational resource. In order to reduce time expenditures in the process of updating the educational material for a particular discipline, it is proposed to establish the relationship between the components of the educational process by identifying intersubject communications, which are considered as a means of achieving the applied orientation of the discipline, at the stage of selecting the necessary information. The formation of students’ self-organization skills has been carried out on the basis of data from a frequency analysis of the network information sources. The results of frequency analysis and statistical processing of experimental data show the ability to make a forecast about the weight of specific topics for future professional activities, which will allow to distribute study time correctly. The use of established intersubject communications of disciplines and the fulfillment of the selected conditions contribute to the development of students’ educational activities self-organization.
Methods for Checking Graduate Qualifying Thesis for the Volume of Borrowing
Authors: Kutsiy Oleg Ya. , Tsibizova Tatiana Yu. , Shevtsova Ekaterina V. , Komkova Tatiana Yu.
Published: December 2020

The article is devoted to the issues of checking a graduate qualifying thesis for the volume of borrowed text and the problems of controlling the circumvention of this check. We considered some variants of widely used methods of verification bypass in MS Word documents, a method of the bypass, because of which a large amount of the unique text will take part in the verification. We analyzed various ways of implementing this method in MS Word documents and considered options for software and manual control of this method.
Determining the Smart University Infrastructure Development Level Based on Data Models
Authors: Mitrofanova Yana S. , Konovalova Svetlana A. , Burenina Valentina I.
Published: December 2020

The paper presents applied research in the framework of solving determining the smart university infrastructure development level problem. Today, all digital transformation and transition to the digital economy concept and smart society development issues are very important. Education is the intellectual core of the digital transformation, the knowledge base, and the training center for the digital economy. Therefore, more attention should be paid to the creation and development of the smart university infrastructure. The purpose of the study is to develop criteria and models for determining the level of smart university infrastructure development. To describe the management of infrastructure level assessment, we propose to use adapted mathematical methods, structural analysis, and mathematical statistics methods. The study examines trends in the development of smart education, highlights the main elements of the smart university infrastructure (technological and organizational), and examines approaches to determining the level of its development based on data models. Taking into account the diversity and volume of quantitative and qualitative indicators of the smart university infrastructure, we propose to measure the level of the infrastructure using data models and Educational Data Mining tools. Universities can use got models when forming a development strategy or selecting funding directions, to reduce the time of digital transformation and transition to the optimal state of a smart university, to prepare for accreditation or to align the smart infrastructure of individual departments.
Designing a Digital Educational Environment for Implementing Comprehensive Changes in the Teacher’s Pedagogical Activities
Authors: Stymkovskiy Vladimir I. , Sergeeva Marina G. , Oreshkina Anna K. , Chernega Elena V.
Published: December 2020

At present, in Russia there is a contradiction between the familiar, time-tested, and innovative technologies in the field of education. It is possible to overcome this conflict by combining full-time and distance learning in the context of a digital educational environment that requires certain applied skills from an educational institution employee. Special operational systems that integrate information from related sciences may be the basis of the digital educational environment in the context of the application of information management technologies. Such systems are required to facilitate the unification, accumulation and preservation of knowledge, as well as ensuring free access to intellectual resources. The authors of the article identified four basic functions of the application of information-type technologies during the training of future representatives of a particular profession: informational and educational, formative, estimative and corrective, research. It is noted that these functions do not act separately, but as elements of a single system, depending on conditions determined by the characteristics of the information educational environment. The analysis allows the authors to argue that at this stage of the educational process evolution, the main task is to create a methodology related to the use of information management technologies in the development of educational electronic materials and their implementation in the context of pedagogical activity.
Spatial Planning for Future Risk Reduction in Coastal Area (Case Study: Kalanganyar Village, Sidoarjo)
Authors: Mutia Fairuz , Nurul Yunisya Adibah , Elviana Eva
Published: December 2020

There is an urgent need for cities to consider disaster and climate change issues. Disasters have caused major disruptions in low- and middle- income countries, often wiping out decades of development benefits in a few moments. Including Kalanganyar, which is geographically located in the hazard-prone. This village has no sandy beach area and directly facing the mangrove forest as the outermost boundary. Since 2/3 of the area is aquaculture, this has resulted in some areas lacking adequate mangrove forests. Therefore, Kalanganyar area becomes prone to tsunami hazards as well as river/tidal flooding. Therefore, disaster risk assessment is needed as input data in spatial planning and spatial planning of Kalanganyar Village as a disaster preventive action. This research is qualitative research with a phenomenology approach. The results of the data tape were analyzed by synchronic reading. Character appraisal is used to assess the eight principles of urban resilience design. The goal is to produce an anticipatory spatial planning concept for the natural disaster, the existing disaster of natural disasters but also human-caused disasters. From the results of character appraisal reading on the area, it was found that the urban fabric is less resilient. This is also coupled with some of the more frequent natural disasters that are floods and tsunamis. This then becomes the basis for the spatial development of disaster-prone areas and meets the overall parameters. Spatial area arrangement is done to anticipate future and future disasters, with more compact urban fabric arrangement, restoring ecological mangrove function according to standard, and also equitable distribution of village facilities and infrastructure so that the area is well developed and planned. This research can be a good and appropriate preventive action for the region.
Shaking Table Tests on a Deformation Mitigation Method for Existing Road Embankment during Liquefaction by Using Gravel and Geosynthetics
Authors: Yoshida Masaho , Katsumi Taiga , Kawasaki Hajime
Published: December 2020

Small scale shaking table tests in a 1-g gravity field were carried out to evaluate effectiveness of a deformation mitigation method for an existing road embankment during liquefaction by using geosynthetics sandwiched between gravel layer and a gabion. The gravel layer could dissipate an excess pore water pressure during liquefaction immediately, and perform as a rigid plate below a slope of embankment. Furthermore, the gabion could confine the slope of embankment and restrain the lateral movement of slope. As a result, these functions could restrain the deformation of embankment, and keep the shape of embankment and flatness of crest.
Grouting performance of the Pandan Duri dam shacked by Lombok earthquake 2018
Authors: Agustawijaya Didi S. , Wahyudi Muji , Yasa I Wayan , Ashari Keke F. , Agustawijaya Ausa R.
Published: December 2020

The Pandan Duri dam has an important role in water supply in the East Lombok District. Unfortunately, Lombok Island is located in a relatively high seismic risk area, as earthquakes occurred in 2018 have ruined almost one third of the island and destroyed thousands of buildings. The Pandan Duri dam is one of many infrastructures shacked by the earthquake. Modelling the dam shows that the grouting installation of the dam has supported the dam after the earthquake. The factor of safety (FoS) of the dam was still 1. 76 after the earthquake for the flood water level conditions; but, the displacements could be significant to the stability of the dam, as the dam might displace up to 1. 64 m. Although, the current grouting support system might provide the stability to the dam during earthquake events, the dam will certainly require further stability enhancement and close monitoring for possible similar events in the future.
The Subgrade Improvement of the Road Construction with Geotextile Reinforcement on Kolaka Clay
Authors: Irdhiani  , Martini
Published: December 2020

Subgrade is an important part of road construction. Construction built on fine-grained subgrade such as clay is very susceptible to damage. The purpose of this study was to determine the CBR value with and without geotextile reinforcement as well as to know the effect of geotextile placement on CBR value. Soil material samples was from Kolaka Village, Mori Atas District, North Morowali Regency, Central Sulawesi Province and the geotextile material used was the Woven UW-150 type. Geotextile used for CBR testing was 2 reinforcement sheets with 6 variations of geotextile placement that are successively on each space 1 and 2, 1 and 3, 1 and 4, 2 and 3, 2 and 4 and 3 and 4. The distance between spaces was 3 cm. According to the Unified Classification System, soil samples were included in the CH group (non-organic clays with high plasticity, fat clays), and according to AASTHO was classified in the A-7-5 (53) group, that is clay. Compaction test resulted an optimum water content of 20. 80% and maximum dry density of 1. 54 gr/cm3. Laboratory CBR values without reinforcement at soaked and unsoaked conditions were respectively 4. 61% and 9. 68%. The farther the distance between reinforcement as well as the farther the reinforcement distance to the ground surface, the greater the CBR value gained.
Synchronous Buck Converter for Improved Maximum Power Extraction on Small Stand-Alone Wind Power System using Modified perturb and observe (P&O)
Authors: Mahmudi Irwan , Mar’atus Sholihah Ratih , Muchlis Baso , Sada Maripi Sundun , Lukman
Published: December 2020

To increase the extraction power of a wind power system, the system must work at peak power. This paper presents maximum power extraction and control systems using a modified perturb and observe algorithm (MP&O) to achieve high efficiency maximum power extraction of wind turbines that connected to permanent magnet synchronous generators (PMSG). To get maximum power from PMSG, MP&O controls the duty cycle of synchronous buck based on the output power of the 12 pulses rectifier. The simulation results show that MP&O can work optimally at every change of wind speed. MP&O was also tested and compared with simple P&O in terms of ripples under stable conditions, response speed and ability to obtain maximum energy output. The average efficiency and convergence time achieved by MP&O are 99. 24% and 0. 71s.
Real Time Monitoring of Salinity Gradient and Solar Pond Temperatures
Authors: Muslimin Zaenab , Siswanto Agus , Chaerah Gunadin Indar , Anshar Muhammad
Published: December 2020

Electric energy is an important factor for human needs, functions as lighting, and various human activities. The large amount of electrical energy needs demands to create various alternative electrical energy. Alternative energy uses renewable energy sources to avoid crisis and energy scarcity. The National Energy Policy (KEN) has encouraged the government and the private sector and the public to use energy effectively and efficiently, and to utilize renewable energy. The direction of national energy policy includes reducing dependence on fossil fuels, specifically petroleum. Utilization of renewable energy is needed for the sustainability of national energy supply and reserves. Indonesia is called a maritime country, because 2/3 of Indonesia’s territory is the sea with the longest coastline in the world, which is ± 80,791. 42 Km and is also called an archipelagic country because it has thousands of islands. This natural situation is a great potential for the development of renewable energy, especially the energy sourced from the sea spread wide and very abundant, namely solar pond. One of the alternative sources of renewable energy sourced from the sea currently not developed in Indonesia is solar ponds, even though Indonesia has a huge geographical potential to develop this technology. There are at least two potential parameters for building a solar pond, first because Indonesia has a tropical climate with a large enough intensity of sun, second because Indonesia is a maritime country surrounded by sea, so the availability of raw water is very abundant. Solar pond is not a new power generation technology. In the history of electricity generation technology in Indonesia, this technology has never been tested and implemented at all. In this study, it has a long-term goal of generating electricity from solar ponds. Solar pond technology is a type of environmentally friendly power plant, based on seawater using sunlight to get the difference in heat in the solar pool so that the thermal layer can be converted into electrical energy. The specific targets, namely data salinity and temperature data on the prototype solar pond have been realized in the form of cylindrical with a height of 1. 05m and a diameter of 0. 8 meters. Solar pool research, in line with the goal of national transformation as a significant contributor to the benefit of the Indonesian Maritime Continent. In line with the development of electricity generation technology, solar pond technology has never been implemented in Indonesia, so this research is in accordance with the 2016-2020 National Strategic Plan number 51868 / UN4. 1 / PR. 04 / 2016.
Analysis of Water Availability in Omu Watershed
Authors: Galib Ishak M. , Wayan Sutapa I , Basong Armin , Dedi Aditya
Published: December 2020

The availability of water in the Omu watershed becomes an important factor for residents in carrying out their activities, very it is important to know the available discharge and water requirements. This study aims to determine the amount of water availability in the Omu watershed based on the method FJ. MOCK, NRECA, and SMEC. This research uses average monthly rainfall data of Tuva station, average monthly climatology data of Bora station, data of catchment area, and land use. The result of the calculation of Omu watershed water availability by using the method of FJ. MOCK, NRECA, and SMEC; obtained the average discharge 2. 21 m3/sec, 2. 30 m3/sec, 2. 85 m3/sec, the maximum discharge happened in June 2. 36 m3/sec, in March 3. 63 m3/sec, in June 3. 58 m3/sec, and while the minimum discharge happened in July 1. 72 m3/sec, in January 0. 84 m3/sec, in February 2. 12 m3/sec. The result of instantaneous discharge measurement in the field is 2. 18 m3/sec. Based on the comparison of the results of the analysis of the water availability data on the Omu watershed, from the three methods closest to the instantaneous discharge value is the FJ. MOCK method.