bluuebunny/crossref_metadata_2025 huggingface dataset:
Crumbling Cookie Categories: Deconstructing Common Cookie Categories to Create Categories that People Understand
Authors: Jiwani Soha , Sasheendran Rachna , Abhyankar Adhishree , Bouma-Sims Elijah , Cranor Lorrie
Published: June 2024

Users of online services often encounter cookie banners that ask them to consent to different categories of cookies. Frequently, these categories are labelled using the four categories defined by the 2012 Cookie Guide from the UK's International Chamber of Commerce (ICC). However, prior research suggests that users have difficulty understanding what these category labels actually mean. We conducted a four-part study to identify labels that more intuitively convey the four cookie categories. First, we crowd sourced new category labels. We then evaluated users' comprehension and sentiment towards the labels in a series of surveys focused on definitions and hypothetical scenarios. Finally, we selected a new slate of category labels based on the results of the prior surveys, and conducted a between-subjects, online behavioral experiment to compare the new slate with the original labels. We ultimately recommend that the industry adopt the category label ``anonymous analytics cookies'' in lieu of the term ``performance cookies'' and ``extra functionality cookies'' instead of ``functional cookies.'' Adopting our recommended terms would both improve the usability of current cookie consent interfaces and any future privacy consent mechanisms that use the same categorization. We also recommend revisiting the categories themselves as the distinctions between these categories do not seem to be well understood and may not reflect useful distinctions for privacy decision making.
Privacy-Preserving Fingerprinting Against Collusion and Correlation Threats in Genomic Data
Authors: Ji Tianxi , Ayday Erman , Yilmaz Emre , Li Pan
Published: June 2024

Sharing genomic databases is critical to the collaborative research in computational biology. A shared database is more informative than specific genome-wide association studies (GWAS) statistics as it enables do-it-yourself calculations. Genomic databases involve intellectual efforts from the curator and sensitive information of participants, thus in the course of data sharing, the curator (database owner) should be able to prevent unauthorized redistributions and protect genomic data privacy. As it becomes increasingly common for a single database be shared with multiple recipients, the shared genomic database should also be robust against collusion attack, where multiple malicious recipients combine their individual copies to forge a pirated one with the hope that none of them can be traced back. The strong correlation among genomic entries also make the shared database vulnerable to attacks that leverage the public correlation models. In this paper, we assess the robustness of shared genomic database under both collusion and correlation threats. To this end, we first develop a novel genomic database fingerprinting scheme, called Gen-Scope. It achieves both copyright protection (by enabling traceability) and privacy preservation (via local differential privacy) for the shared genomic databases. To defend against collusion attacks, we augment Gen-Scope with a powerful traitor tracing technique, i.e., the Tardos codes. Via experiments using a real-world genomic database, we show that Gen-Scope achieves strong fingerprint robustness, e.g., the fingerprint cannot be compromised even if the attacker changes 45% of the entries in its received fingerprinted copy and colluders will be detected with high probability. Additionally, Gen-Scope outperforms the considered baseline methods. Under the same privacy and copyright guarantees, the accuracy of the fingerprinted genomic database obtained by Gen-Scope is around 10% higher than that achieved by the baseline, and in terms of preservations of GWAS statistics, the consistency of variant-phenotype associations can be about 20% higher. Notably, we also empirically show that Gen-Scope can identify at least one of the colluders even if malicious receipts collude after independent correlation attacks.
Stent A pancreaticojejunostomy after pancreatoduodenectomy: Is it always necessary?
Authors: Symeonidis Dimitrios , Zacharoulis Dimitris , Tzovaras Georgios , Kissa Labrini , Samara Athina A , Petsa Eleana , Tepetes Konstantinos
Published: June 2024

The establishment of a postoperative pancreatic fistula (POPF) is considered the most common and, concomitantly, the most serious complication associated with pancreaticoduodenectomy (PD). The search for either technical modifications of the operative technique or pharmaceutical interventions that could possibly aid in decreasing the incidence of this often-devastating complication appears justified. The stenting of the pancreatic duct, with the use of either internal or external stents, has been evaluated in this direction. In theory, it is an approach that could eliminate many pathophysiological factors responsible for the occurrence of a POPF. The purpose of the present study was to review the current data regarding the role of pancreatic duct stenting on the incidence of POPF, after PD, by using PubMed and Reference Citation Analysis. In general, previous studies seem to highlight the superiority of external stents over their internal counterparts in regard to the incidence of POPF; this is at the cost, however, of increased morbidity associated mainly with the stent removal. Certainly, the use of an internal stent is a less invasive approach with acceptable results and is definitely deprived of the drawbacks arising through the complete diversion of pancreatic juice from the gastrointestinal tract. Bearing in mind the scarcity of high-quality data on the subject, an approach of reserving stent placement for the high-risk for POPF patients and individualizing the selection between the use of an internal or an external stent according to the distinct characteristics of each individual case scenario appears appropriate.
Ensemble for evaluating diagnostic efficacy of non-invasive indices in predicting liver fibrosis in untreated hepatitis C virus population
Authors: Kaur Navneet , Goyal Gitanjali , Garg Ravinder , Tapasvi Chaitanya , Demirbaga Umit
Published: June 2024

BACKGROUND

Hepatitis C virus (HCV) infection progresses through various phases, starting with inflammation and ending with hepatocellular carcinoma. There are several invasive and non-invasive methods to diagnose chronic HCV infection. The invasive methods have their benefits but are linked to morbidity and complications. Thus, it is important to analyze the potential of non-invasive methods as an alternative. Shear wave elastography (SWE) is a non-invasive imaging tool widely validated in clinical and research studies as a surrogate marker of liver fibrosis. Liver fibrosis determination by invasive liver biopsy and non-invasive SWE agree closely in clinical studies and therefore both are gold standards.

AIM

To analyzed the diagnostic efficacy of non-invasive indices [serum fibronectin, aspartate aminotransferase to platelet ratio index (APRI), alanine aminotransferase ratio (AAR), and fibrosis-4 (FIB-4)] in relation to SWE. We have used an Artificial Intelligence method to predict the severity of liver fibrosis and uncover the complex relationship between non-invasive indices and fibrosis severity.

METHODS

We have conducted a hospital-based study considering 100 untreated patients detected as HCV positive using a quantitative Real-Time Polymerase Chain Reaction assay. We performed statistical and probabilistic analyses to determine the relationship between non-invasive indices and the severity of fibrosis. We also used standard diagnostic methods to measure the diagnostic accuracy for all the subjects.

RESULTS

The results of our study showed that fibronectin is a highly accurate diagnostic tool for predicting fibrosis stages (mild, moderate, and severe). This was based on its sensitivity (100%, 92.2%, 96.2%), specificity (96%, 100%, 98.6%), Youden’s index (0.960, 0.922, 0.948), area under receiver operating characteristic curve (0.999, 0.993, 0.922), and Likelihood test (LR+ > 10 and LR- < 0.1). Additionally, our Bayesian Network analysis revealed that fibronectin (> 200), AAR (> 1), APRI (> 3), and FIB-4 (> 4) were all strongly associated with patients who had severe fibrosis, with a 100% probability.

CONCLUSION

We have found a strong correlation between fibronectin and liver fibrosis progression in HCV patients. Additionally, we observed that the severity of liver fibrosis increases with an increase in the non-invasive indices that we investigated.
Violence study of healthcare workers and systems in the Caribbean: ViSHWaS-Caribbean study
Authors: Hadmon Reshon , Pierre Daniella Myriam , Banga Akshat , Clerville Jacques W , Mautong Hans , Akinsanya Precious , Gupta Rajat Das , Soliman Sama , Hunjah Tolupe M , Hunjah Bamidele A , Hamza Hafeez , Qasba Ruman Khurshid , Nawaz Faisal A , Surani Salim , Kashyap Rahul
Published: June 2024

BACKGROUND

Violence against healthcare workers (HCWs) in the Caribbean continues to prevail yet remains underreported. Our aim is to determine the cause, traits, and consequences of violence on HCWs in the Caribbean.

AIM

To determine the cause, traits, and consequences of violence on HCWs in the Caribbean.

METHODS

This research adopted an online cross-sectional survey approach, spanning over eight weeks (between June 6th and August 9th, 2022). The survey was generated using Research Electronic Data Capture forms and followed a snowballing strategy to contact individuals using emails, social media, text messages, etc. Logistic regression analysis was performed to evaluate the variables that influence violence, including gender, age, years of experience, institution type, and night shift frequency.

RESULTS

The survey was completed by 225 HCWs. Females comprised 61%. Over 51% of respondents belonged to the 21 to 35 age group. Dominica (n = 61), Haiti (n = 50), and Grenada (n = 31) had the most responses. Most HCWs (49%) worked for government academic institutions, followed by community hospitals (23%). Medical students (32%), followed by attending physicians (22%), and others (16%) comprised the most common cadre of respondents. About 39% of the participants reported experiencing violence themselves, and 18% reported violence against colleague(s). Verbal violence (48%), emotional abuse (24%), and physical misconduct (14%) were the most common types of violence. Nearly 63% of respondents identified patients or their relatives as the most frequent aggressors. Univariate logistic regression analyses demonstrated that female gender (OR = 2.08; 95%CI: 1.16-3.76, P = 0.014) and higher frequency of night shifts (OR = 2.22; 95%CI: 1.08-4.58, P = 0.030) were associated with significantly higher odds of experiencing violence. More than 50% of HCWs felt less motivated and had decreased job satisfaction post-violent conduct.

CONCLUSION

A large proportion of HCWS in the Caribbean are exposed to violence, yet the phenomenon remains underreported. As a result, HCWs’ job satisfaction has diminished.
Botulinum toxin type A for treating chronic low back pain: A double blinded randomized control study
Authors: Jain Mantu , Khan Shahnawaz , Varghese Paulson , Tripathy Sujit Kumar , Mangaraj Manaswini
Published: June 2024

BACKGROUND

Low back pain (LBP) is a prevalent issue that orthopedic surgeons frequently address in the outpatient setting. LBP can arise from various causes, with stiffness in the paraspinal muscles being a notable contributor. The administration of Botulinum toxin type A (BoNT-A) has been found to alleviate back pain by relaxing these stiff muscles. While BoNT-A is approved for use in numerous conditions, a limited number of randomized clinical trials (RCTs) validate its efficacy specifically for treating LBP.

AIM

To study the safety and the efficacy of BoNT-A in minimizing pain and improving functional outcomes in patients of chronic LBP (CLBP).

METHODS

In this RCT, adults aged 18-60 years with mechanical LBP persisting for at least six months were enrolled. Participants were allocated to either the Drug group, receiving 200 Ipsen Units (2 mL) of BoNT-A, or the Control group, which received a 2 mL placebo. Over a 2-month follow-up period, both groups were assessed using the Visual Analog Scale (VAS) for pain intensity and the Oswestry Disability Index (ODI) for disability at the start and conclusion of the study. A decrease in pain by 50% was deemed clinically significant.

RESULTS

The study followed 40 patients for two months, with 20 in each group. A clinically significant reduction in pain was observed in 36 participants. There was a statistically significant decrease in both VAS and ODI scores in the groups at the end of two months. Nonetheless, when comparing the mean score changes, only the reduction in ODI scores (15 in the placebo group vs 16.5 in the drug group, clinically insignificant) was statistically significant (P = 0.012), whereas the change in mean VAS scores was not significant (P = 0.45).

CONCLUSION

The study concludes that BoNT-A does not offer a short-term advantage over placebo in reducing pain or improving LBP scores in CLBP patients.
Ethical framework for artificial intelligence in healthcare research: A path to integrity
Authors: Abujaber Ahmad A , Nashwan Abdulqadir J
Published: June 2024

The integration of Artificial Intelligence (AI) into healthcare research promises unprecedented advancements in medical diagnostics, treatment personalization, and patient care management. However, these innovations also bring forth significant ethical challenges that must be addressed to maintain public trust, ensure patient safety, and uphold data integrity. This article sets out to introduce a detailed framework designed to steer governance and offer a systematic method for assuring that AI applications in healthcare research are developed and executed with integrity and adherence to medical research ethics.
Arquitectura autónoma
Authors:   Universidad La Salle Oaxaca, Hernández Altamirano Christian Alan
Published: June 2024

Dados sus atributos para brindar confort, sustentabilidad y eficiencia energética, la domótica cobra cada vez más impacto en la construcción; a pesar de ello, al proyectar, pocos constructores contemplan la domótica.Actualmente, el desarrollo tecnológico ha hecho realidad la posibilidad de controlar nuestros hogares desde la palma de la mano. Gracias a este desarrollo tecnológico, en la arquitectura se ha implementado una nueva tecnología, la domótica; inicialmente, ésta constituyó una respuesta al acelerado incremento de nuestro ritmo de vida. Hoy en día, nuestra vida se encuentra inmersa en múltiples sistemas tecnológicos.
The Impact of Social Media Engagement on Friendship and Relationship Quality
Authors: Clayton Brianna , Talpade Medha
Published: June 2024

The purpose of this study is to test the theory of how social media impacts the relationship of young men and women that compares the time spent on social media to the quality of relationships, both platonic and romantic, for students studying psychology at Clark Atlanta University. Past research on generation Z adults indicated that there has been a great decrease in interest in being in a monogamous relationship. This study is unique because not only does it focus on romantic relationships, but it includes friendships and how social media may play a significant factor. The hypothesis of the present study was that student social media activities will have an impact on relationship and friendship quality. The participants were Clark Atlanta students studying psychology. The data collection method was a survey created on Qualtrics. The results indicated that the participants do love their partners; however, desire more. Research shows that they are not necessarily satisfied in their relationships and that it does not meet their original expectations. Within their friendships, they have disagreements every so often, but they are able to maintain a healthy relationship as they practice good communication between one another. The majority stated that their most used application is a social media platform with an average of 15 hours a week. The expectations were thus confirmed. Implications of the results for future studies include a longitudinal study on the role of social media in romantic commitments. The results of this study can contribute to the field of psychology and help initiate positive change for young adults and adolescents who are currently consumed by social media and digital realities and ideas they acquire due to their excessive usage.
PENGARUH PERTUMBUHAN PENJUALAN, LIKUIDITAS DAN UKURAN PERUSAHAAN TERHADAP PROFITABILITAS PADA PERUSAHAAN SEKTOR PROPERTIES DAN REAL ESTATE DI BEI PERIODE 2019-2022
Authors: Rafli Raflie , Ikhsan Syarbini
Published: June 2024

Penelitian ini bertujuan untuk mengetahui pengaruh pertumbuhan penjualan terhadap profitabilitas, untuk mengetahui pengaruh likuiditas terhadap profitabilitas, untuk mengetahui pengaruh ukuran perusahaan terhadap profitabilitas pada perusahaan Property & Real Estate yang terdaftar di Bursa Efek Indonesia Tahun 2019-2022. Jumlah populasi dalam penelitian ini adalah 92 perusahaan dan sampel dalam penelitian ini adalah berjumlah 56 perusahaan dengan 4 tahun penelitian dan total yang di dapat 224 data. Teknik analisis yang digunakan adalah regresi linier berganda dengan menggunakan SPSS. Hasil penelitian menunjukkan bahwa pertumbuhan penjualan dan likuiditas berpengaruh positif dan signifikan terhadap profitabilitas, dan sebaliknya ukuran perusahaan berpengaruh positif tidak signifikan terhadap profitabilitas pada Perusahaan Property & Real Estate di Bursa Efek Indonesia.
Analysis of the Relationship between Speed Consistency and Traffic Accident Probability (on the Mojokerto-Surabaya Toll Road)
Authors:   Universitas Indonesia, Risfiandi Riki , Siregar Martha Leni
Published: June 2024

Vehicle speed consistency plays a crucial role in maintaining traffic safety, with speed limits set to reduce accident fatalities. While the direct impact of speed limits on vehicle speed is minimal, their implementation significantly influences driver behavior, with about 85% of drivers complying with speed limits. However, variables such as traffic volume, weather conditions, and travel urgency often cause drivers to be inconsistent in adhering to these limits, increasing accident risk. On the Mojokerto-Surabaya toll road, data from IRSMS Korlantas Polri and Jasa Marga recorded 193 accidents with 101 fatalities from 2018 to August 2023, mostly caused by driver behavior such as excessive speed. This study analyzes the relationship between speed consistency and accident probability on this road, highlighting accident issues due to speed violations and inconsistency at ramp off/on locations. Results show the importance of toll road infrastructure considering vehicle volume, identifying accident blackspots, and implementing urgent speed management as key factors in improving safety on the Surabaya-Mojokerto toll road. The findings emphasize the need for better traffic management and speed regulation to reduce fatal accident risks.
Impact of Auxiliary Markings on Intersection Safety
Authors:   Universitas Indonesia, Tommy Mhd , Siregar Martha Leni , Kusuma Andyka
Published: June 2024

The rapid growth of motorcycle vehicles coupled with inadequate traffic discipline contributes to an escalating rate of traffic accidents and casualties. This study investigates the efficacy of auxiliary road markings in enhancing traffic safety and intersection performance along Lieutenant Sutopo Street, Promoter Street, and Boulevard BSD East in South Tangerang, Indonesia. Employing the Traffic Conflict Technique (TCT), the research evaluates safety enhancements and service level alterations subsequent to the installation of road markings. Preliminary observations highlight significant safety concerns and traffic conflicts at the intersection. Consequently, auxiliary road markings are strategically installed to regulate driver behavior, enhance lane discipline, and improve visibility. Post-installation observations revealed a significant decrease in total vehicle conflicts, though the percentage of severe conflicts slightly increased. Initially rated as Level of Service (LOS) F with high delays, the LOS remained the same post-marking installation but with reduced delays. Further cycle time adjustments improved the LOS to E, indicating a substantial overall reduction in delays. The findings suggest that although auxiliary road markings effectively reduce traffic conflicts and improve intersection performance, additional measures are necessary to address the severity of these conflicts. The study offers valuable insights into the effectiveness of road safety interventions, supporting broader strategies for improving traffic management and safety in urban areas.
Evaluation of Coal Transport Route in Jambi City (Talang Duku Port-East Ring Road II)
Authors:   Universitas Indonesia, Angella Dwi , Soehodho Sutanto , Yusuf Nahry
Published: June 2024

In its implementation, the role of coal transportation infrastructure is important in supporting the mining industry in Jambi City. However, it also causes various complex problems; one of them is traffic congestion on arterial roads in Jambi City. In May 2023, the Jambi Regional Police of the Republic of Indonesia issued a notification letter to stop the mobilization of coal transportation in Jambi Province. The policy caused several coal companies to switch their transportation method to shipping in order to continue operating, while several other companies stopped operating until an indeterminate time. Therefore, this study aims to compare traffic performance before and after the implementation of the policy on Jambi City arterial roads, especially on Talang Duku Port Road and East Ring Road II. The method used was a comparative analysis of the degree of saturation before and after the enactment of regulations on the prohibition of coal truck operations. The results of this study show the importance of traffic management as one of the solutions to reduce traffic congestion. Nevertheless, other alternatives are still needed to support the smooth operation of coal transportation activities.
Managing Consumer Anger And Consumer Forgiveness Through Service Recovery Strategies In Transportation Sector
Authors: Gul Sabahat , Saeed Adnan
Published: June 2024

The purpose of this study was to examine the effect of service failure severity and consumer anger towards consumer forgiveness and empirically examine the relationship of the effective recovery strategies, consumer forgiveness, and their outcome. Total data was collected from 250 commuters of organized bus services. The survey technique was used for data collection from the commuters of organized bus services. This study was analyzed the data with the help of the data statistical package for social science (SPSS) AMOS version 21 will be used for analyzing the data. The findings reveal that service failure severity and consumer anger have significantly negative related to consumer forgiveness and apology as effective recovery strategy was led more to consumer forgiveness. This research only focuses on one company as one of the limitations of this research that may influence the results presented in this study. The current study is limited to empirically test the direct relationship with consumer forgiveness. This research used non-probability sampling techniques, which cannot describe all the population in Lahore. Service failure severity reduces the willingness of forgiveness and service providers should check all factors that lead to the severity of services. Most importantly, the current study demonstrated that an effective recovery strategy requires the right recovery strategy which leads to consumer forgiveness.
Geo-sustainable Practices in Urban Agriculture: A Study of Sustainable Land Use and Natural Resource Conservation at Household Level
Authors: Alam Arhama Noor , Naeem Saira
Published: June 2024

This study explores urban agriculture as a solution to food insecurity in Lahore, Pakistan, amid rapid urbanization and declining agricultural productivity. Using a mixed methods approach, the research assesses the current state of urban agriculture, community willingness to adopt such practices, and the factors influencing this adoption. Data was collected from households in Johar Town and Faisal Town through surveys, complemented by a literature review of global urban agriculture policies. The findings reveal limited practice of urban agriculture but significant willingness among residents, driven by factors such as self-reliance, high food prices, and health concerns. However, barriers like lack of access to land, guidance, and time hinder widespread adoption. The socio-economic profile of respondents indicates varied interest and awareness based on age, income, and household size. The study emphasizes the need for policies promoting urban agriculture, including community gardens, vertical farms, and wastewater reuse. Educational campaigns and professional training are essential to raise awareness and build skills among urban dwellers. The research concludes that urban agriculture can enhance food security and sustainability in Lahore with robust policy support and community engagement. Future research should expand the study area, use more nuanced data collection methods, and explore the economic viability of urban agriculture initiatives. Such efforts aim to advance urban agriculture practices and policies in Lahore, making the city more self-sufficient and resilient in food production.
ANALYSIS OF PHYSICO-CHEMICAL PARAMETERS OF RIVER GARRA AT SHAHJAHANPUR (U.P.)
Authors: Nidhi Tripathi,Ramesh Chandra and Dev Priya Gautam
Published: June 2024

The ecosystem and way of life in the area around Shahjahanpur, Uttar Pradesh, are greatly influenced by the River Garra, a tributary of the Gomati River. The objective of this study was to evaluate the river water's physico-chemical characteristics at many Shahjahanpur sampling locations in order to ascertain its quality and suitability for diverse uses. A thorough examination of variables like pH, temperature, and alkalinity was done. During the dry, cold, and wet seasons, water samples were taken from five distinct places along the Garra River in the Shahjahanpur area. The physico-chemical parameters were measured using standard analytical techniques, guaranteeing precise and trustworthy findings.
By examining important pH, temperature, and alkalinity factors, the study sheds light on the condition of this crucial aquatic habitat. The possible effects of the Garra River on biodiversity are covered in the report. The summer, winter, and rainy seasons differ greatly in terms of alkalinity, temperature, and pH. Upstream, the water had no color, but downstream, it turned brunette. The river's alkalinity varies from a minimum of 78 mg/l at Site D in the winter to a maximum of 219 mg/l at Site B in the summer. The pH of the river ranges from a minimum of 8.07 at Site D in the summer to a maximum of 8.53 at Site B. The river's temperature varies throughout the year, with a minimum of 8.3 0C at Site D during the winter and a maximum of 31.5 0C at Site B during the summer.
The T-cell receptor β chain CDR3 insights of bovine liver immune repertoire under heat stress
Authors: Hui Linhu , Wu Fengli , Xu Yuanyuan , Yang Guangjun , Luo Qiaorong , Li Yangyang , Ma Long , Yao Xinsheng , Li Jun
Published: June 2024

Objective: The liver plays a dual role in regulating temperature and immune responses. Examining the influence of heat stress (HS) on liver T cells contributes significantly to understanding the intricate interplay between the immune system and hepatic tissues under thermal stress. This study focused on investigating the characteristics of the T-cell receptor (TCR) β chain CDR3 repertoire in bovine liver samples under both HS and pairfed (PF) environmental conditions.Methods: Sequencing data from six samples sourced from the GEO database underwent annotation. Utilizing immunarch and VDJtool software, the study conducted comprehensive analyses encompassing basic evaluation, clonality assessment, immune repertoire comparison, diversity estimation, gene usage profiling, VJ gene segment pairing scrutiny, clonal tracking, and Kmers analysis.Results: All four TCR chains, namely α, β, γ, and δ, were detected, with the α chains exhibiting the highest detection frequency, followed closely by the β chains. The prevalence of αβ TCRs in bovine liver samples underscored their crucial role in governing hepatic tissue's physiological functions. The TCR β CDR3 repertoire showcased substantial inter-individual variability, featuring diverse clonotypes exhibiting distinct amino acid lengths. Intriguingly, HS cattle displayed heightened diversity and clonality, suggesting potential peripheral T cell migration into the liver under environmental conditions. Notably, differential VJ gene pairings were observed in HS cattle compared to the PF, despite individual variations in V and J gene utilization. Additionally, while most high-frequency amino acid 5-mers remained consistent between the HS and PF, GELHF, and YDYHF were notably prevalent in the HS group. Across all samples, a prevalent trend of high-frequency 5mers skewed towards polar and hydrophobic amino acids was evident.Conclusion: This study elucidates the characteristics of liver TCR β chain CDR3 repertoire under HS conditions, enhancing our understanding of HS implications.
A novel p.127Val>Ile single nucleotide polymorphism in the MTNR1A gene and its relation to litter size in Thin-tailed Indonesian ewes
Authors: Abuzahra Mutasem , Al-Shuhaib Mohammed Baqur S. , Wijayanti Dwi , Effendi Mustofa Helmi , Mustofa Imam , Moses Ikechukwu Benjamin
Published: June 2024

Objective: The primary objective was to identify and characterize the single nucleotide polymorphisms (SNPs) within the MTNR1A gene sequence in Thin-tailed Indonesian ewes to assess the possible association of MTNR1A gene polymorphism with litter size trait.Methods: Forty-seven Thin-tailed Indonesian sheep were selected for the study. Genotyping involved collecting blood samples, and sequencing exon 2 of the MTNR1A gene.Results: The study identified 19 novel SNPs, with 10 being non-synonymous variations, in the MTNR1A gene of Thin-tailed Indonesian ewes. One non-synonymous SNP (rs1087815963) showed a significant association with litter size, with the GC genotype exhibiting a higher average litter size than the GG genotype. The deleterious impact of p.Val127Ile SNP was predicted by various in silico tools that predicted a highly damaging effect of p.Val127Ile SNP on the structure, function, and stability of MTNR1A. Docking reactions showed a critical involvement of this locus with the binding with melatonin.Conclusion: In conclusion, the results of our study suggest that rs1087815963 has a remarkable negative impact on the MTNR1A with a putative alteration in the binding with melatonin. Therefore, the implementation of the novel p.Val127Ile could be a useful marker in marker-assisted selection.
PERFORMATIVIDADE E ALGUNS DOS SEUS EFEITOS NA ORIENTAÇÃO DA FORMAÇÃO E DO TRABALHO DOCENTE NO BRASIL
Authors: Scherer Susana
Published: June 2024

O presente texto se dedica a analisar a presença e alguns dos efeitos da performatividade, no contexto da construção de uma escola gerencial, na orientação da formação e do trabalho docente no Brasil. Com base na abordagem metodológica macro-global e micro-local da sociologia da educação, são aclaradas as vinculações entre as atuais estratégias neoliberais e a gestão gerencial e a performatividade. Os estudos apontam que o gerencialismo e a performatividade se manifestam por políticas que visam infiltrar a lógica de mercado no setor público, através do foco em desempenhos. Os resultados da pesquisa sobre o Brasil indicam a construção de uma escola gerencial e de expressões da performatividade em propostas a partir dos anos 90, com o Sistema de Avaliação da Educação Básica (SAEB), seu aperfeiçoamento e desdobramentos na BNCC e propostas como a BNC Docente, Prova Nacional Docente, nova Política Nacional de Formação inicial e continuada de professores para a educação básica, Exame Nacional do Magistério na educação básica (ENAMEB). Dessa forma, analisa-se a que a construção de uma escola gerencial se dá no país para inclinar a educação ao mercado, para o qual a performatividade tem papel chave para orientar a formação e o trabalho docente, deslegitimando o caráter social da educação, da escola e do professor.
DIÁLOGOS POSSÍVEIS ENTRE EVASÃO E PERMANÊNCIA ESCOLAR A PARTIR DAS PESQUISAS E DOS DOCUMENTOS NORMATIVOS SOBRE O ENSINO MÉDIO INTEGRADO NA REDE FEDERAL
Authors: Felippe Jonis Manhães Sales , Lima Sandra Helena de Araujo
Published: June 2024

Os desafios para o enfrentamento da evasão escolar permeiam as discussões sobre a educação brasileira em diferentes contextos históricos e políticos, constituindo-se em uma preocupação não apenas para educadores, mas para toda a sociedade. Visando ampliar a compreensão do fenômeno da evasão, este trabalho promove a sua articulação com o conceito de permanência escolar, que vem ganhando destaque nas produções acadêmicas recentes e nos documentos norteadores da educação no país atualmente. Desse modo, o artigo se apresenta como o resultado de pesquisas documentais e bibliográficas sobre os conceitos de evasão escolar e permanência escolar, com destaque para as suas manifestações no ensino médio integrado da Rede Federal de Educação Científica, Profissional e Tecnológica. Tais pesquisas evidenciaram diferentes percepções conceituais que, não sendo mutuamente excludentes, demonstram que fenômenos da evasão escolar e da permanência escolar, embora diferentes, precisam ser investigados de maneira complementar, tendo como foco a efetiva garantia do direito social à educação.
REGGIO EMILIA:
Authors: Losso Mariela , Civarolo Mercedes
Published: June 2024

Este artigo apresenta uma experiência realizada na Rede Interdisciplinar Iberoamericana de Estudos e Pesquisas sobre Direitos fundamentais e Políticas para o bem-estar integral de Crianças e Jovens – Rede Emili@ (RE), no formato de diálogos sobre infâncias a partir de diferentes epistemologias, perspectivas de pesquisa e práticas. Neste caso apresentamos o diálogo com a Dra. María Mercedes Civarolo e membros da RE.
A entrevista completa foi publicada online no canal Rede Emíli@. O objetivo geral desta série de entrevistas é produzir e divulgar diálogos com referências no campo das Ciências Sociais e Humanas que têm pesquisas em andamento baseadas nos direitos e na reivindicação do papel de meninas e meninos na sociedade. O objetivo específico do diálogo com Mercedes Civarolo foi identificar as características e a particularidade da Pedagogia Reggio Emilia na consideração do principado das crianças e dos seus direitos.
Juntamente com a autora, identificamos os eixos diretamente ligados aos direitos de meninas e meninos, suas condições educacionais e a particularidade da Pedagogia Reggio Emilia em considerar os princípios da infância. Os eixos foram, inicialmente, a relevância de Loris Malaguzzi e da pedagogia Reggio Emilia, na trajetória acadêmica do entrevistado. Em seguida, é levantada a relação entre o Projeto Spectrum e a abordagem de Reggio Emilia. O processo de documentação também é abordado no âmbito desta pedagogia e das suas experiências, a relação com a sua perspectiva antropológica.
Para encerrar o diálogo, a entrevistada sintetiza a imagem de infância a que se refere em sua obra, a ressignificação do ato educativo não mais centrado na voz do professor ou da escola, mas nas vozes de meninas e meninos. Aumentando assim a relevância desta pedagogia em relação aos direitos das crianças. Para ampliar o registro da experiência, apresentamos uma série de imagens que acompanham a conversa e ilustram seu conteúdo com o protagonismo da menina, dos meninos, suas vivências, ações e territórios “reggianos”.
Open VLF: Plataforma de Dados Abertos para Very Low Frequency Data
Authors: Kauffmann Daniel H. V. , Garcia Lucas S. , de Oliveira Rogério
Published: June 2024

Este artigo implementa uma plataforma de dados aberta para sinais VLF (Very Low Frequency). A plataforma integra múltiplos repositórios de dados e oferece funcionalidades de busca, visualização e download de dados coletados nas bases de dados SAVNET e AWESOME, incluindo ferramentas de código aberto e conteúdo informativo. Com uma abordagem modular e escalável, a democratização da informação para estudos sobre clima espacial, erupções solares e fenômenos atmosféricos e eletromagnéticos da ionosfera impacta positivamente a pesquisa e o ensino na área. Além disso, a estrutura da plataforma permite a adaptação a outros tipos de dados e sistemas similares, reforçando o seu carácter expansível e flexível no âmbito da prática da ciência aberta, promovendo a transparência e a colaboração na comunidade científica.
Diretrizes para o Design de Visualizações da Informação: Uma Extensão da Linguagem Simples para Gráficos mais Compreensíveis
Authors: Oliveira Rodrigo , Oliveira Jonice , Cappelli Claudia
Published: June 2024

Em um mundo sobrecarregado de dados, uma comunicação eficaz da informação é essencial, sobretudo para usuários com baixo letramento. Este trabalho une práticas da Linguagem Simples, que lida com o entendimento, com as de Visualização da Informação, que trata de representações gráficas para contribuir no consumo da informação pela população. A pesquisa gerou um Guia com práticas para construção de gráficos de fácil entendimento, o sistema Chart Lab (baseado no Guia), que verifica violações a essas práticas e uma avaliação das visualizações brasileiras sobre a pandemia de COVID-19. Experimentos com usuários demonstram que os artefatos da pesquisa contribuem para tornar a informação mais clara a todos.
Engajamento de Desenvolvedores em Portais de Ecossistemas de Software: Resumo Estendido – CTDSI/CTCCSI 2024
Authors: Parracho Thiago de Moura , Zacarias Rodrigo Oliveira , Santos Rodrigo Pereira dos
Published: June 2024

Contexto: Portais de Ecossistemas de Software (ECOS) são interfaces web que permitem a um desenvolvedor participar de um ecossistema. Motivação: Melhorar o engajamento do desenvolvedor é uma preocupação importante para manter um ECOS sustentável no mercado. A Experiência de Desenvolvedor (DX, do inglês Developer eXperience) afeta o engajamento no portal, podendo ser influenciada pela transparência da informação. Problema: Barreiras encontradas durante a interação com um portal de ECOS dificultam o engajamento e podem fazer com que os desenvolvedores abandonem o portal e, assim, o ecossistema. Objetivo: Este trabalho investiga fatores que afetam o engajamento de desenvolvedores em portais de ECOS. Método de Pesquisa: Foram realizados estudos de caso, uma pesquisa de opinião e um estudo de campo com desenvolvedores e utilizados métodos mistos para a análise de dados. Resultados: 21 fatores que afetam o engajamento foram identificados com base nos relatos dos participantes dos estudos. Contribuições: Busca-se apoiar o engajamento de desenvolvedores em portais de ECOS e fazer sugestões para sua melhoria com base nos relatos dos participantes, promovendo maior satisfação na DX.
Análise Sobre Viés de Gênero no Youtube: um Estudo sobre as Eleições Brasileiras de 2018 e 2022
Authors: Kappaun Andressa , Oliveira Jonice
Published: June 2024

Este trabalho propôs um método para investigar a presença de viés de gênero através da análise do engajamento e sentimento dos comentários em vídeos do YouTube que mencionam homens ou mulheres no título ou na descrição. Os cenários de estudo abrangem as eleições brasileiras de 2018 e 2022, focando nos cargos de presidente, governador e senador. A análise quantitativa, validada estatisticamente pelo teste de chi-quadrado, revelou um maior engajamento em vídeos com homens, acompanhado por uma predominância de sentimentos negativos nos vídeos com mulheres. O método demonstrou eficácia na detecção de viés de gênero, sendo replicável em diferentes contextos, representando, assim, uma contribuição social em termos de valores humanos.
Content and Skills for Teaching BPM in Computer Science Courses: a Systematic Mapping Study
Authors: Nobre Matheus R. B. , Vilela Jéssyka F. F.
Published: June 2024

This study investigates the content and skills explored in the teaching of Business Process Management (BPM). Through a systematic literature review, we aim to understand and highlight the trends and gaps in BPM education. The results offer valuable insights to enhance education and align professionals with market demands.
A Speech Emotion Recognition Model to Detect Aggressive Behavior in Dialogues
Authors: Ferreira Gabriel Gonçalves , Marques Johnny
Published: June 2024

Speech Emotion Recognition (SER) is a multidisciplinary field that involves the development of computational models to automatically detect and analyze emotional states conveyed through speech signals. Utilizing techniques from signal processing, machine learning, and natural language processing, SER systems extract relevant features from audio data and classify emotions into distinct categories such as happiness, sadness, anger, and more. This work aims to leverage the latest SER techniques to build a robust model that can detect aggressive behavior in dialogues solely based on audio input signals.
Acessibilidade em Sistemas Integrados de Gestão Empresarial (ERP): Percepções, Desafios e Impacto no Trabalho de Pessoas com Deficiência Visual: Resumo Estendido – CTDSI/CTCCSI 2024
Authors: Guissoni Ellen Diana Silva de Carvalho , Freire André Pimenta , Araújo Rafael Dias
Published: June 2024

Esta pesquisa foca na acessibilidade em ERPs para deficientes visuais, analisando sua implementação através de entrevistas, inspeções seguindo a WCAG, e um grupo focal com desenvolvedores. Revela o conhecimento limitado dos desenvolvedores sobre acessibilidade e a necessidade de integrar práticas acessíveis no desenvolvimento de ERPs, enfatizando a importância do acesso para deficientes visuais.
Estratégias Computacionais Baseadas em Similaridade de Textos e Visualização Exploratória para a Identificação de Inconsistências em Notas Fiscais Eletrônicas
Authors: Marinho Mayara C. , Weigang Li , Oliveira Vinícius Di , Oliveira Maria Cristina F. , Borges Vinicius R. P.
Published: June 2024

A detecção de fraudes em notas fiscais é um desafio considerável para os órgãos de controle, dada a quantidade expressiva de documentos gerados diariamente. Buscando soluções para esse desafio, esta pesquisa propõe uma abordagem inovadora que combina rotulação automática de notas fiscais baseada em similaridade de texto e técnicas de visualização exploratória. O objetivo é auxiliar especialistas na tarefa de auditoria fiscal, trazendo equilíbrio entre automatização e autonomia por meio de um sistema de visualização web interativo denominado NFViz. O NFViz permite investigar as notas fiscais em busca de incompatibilidades que podem sinalizar possíveis fraudes, otimizando as atividades de auditoria fiscal ao reduzir o escopo de busca por notas suspeitas.
Ferramenta para Auxílio à Auditoria de Editais Municipais para Compra de Medicamentos
Authors: Silva Arthur L. , Sampaio Vicente G. R. C. A. , Lima Adriano M. A. , Cabral George G. , Valença George
Published: June 2024

Gestores de saúde pública publicam editais de licitações para compra de medicamentos contendo listas de princípios ativos de medicamentos e seus respectivos preços unitários, quantidade desejada e total da compra. Os auditores precisam identificar se a precificação declarada está de acordo com os valores de mercado. Essa é uma tarefa manual e sujeita a erros. O presente trabalho propõe uma solução para a automação da fiscalização para compras públicas de medicamentos. A ferramenta proposta foi capaz de, dado um principio ativo e dosagem, identificar produtos similares disponíveis no mercado e assim, baseado em dados de notas fiscais, avaliar se o preço orçado no edital pertence a distribuição de preços de mercado. Os resultados obtidos mostram que a ferramenta é capaz de realizar parte da auditoria para uma grande quantidade de itens.
Um aplicativo para comunicação diária entre equipe terapêutica multidisciplinar e familiares de pessoas com TEA
Authors: Gonzales Ian Jairo T. , Cunha Mônica X. C. da , Carvalho Lukas T.
Published: June 2024

A comunicação eficaz entre pais, professores e terapeutas é crucial para o tratamento de crianças e adolescentes com autismo. Este artigo descreve o desenvolvimento de um aplicativo móvel para auxiliar essa comunicação. O aplicativo foi projetado com base em entrevistas e em observações em uma instituição de tratamento para autismo. Suas funcionalidades foram aprovadas pelos membros da instituição e implementadas utilizando o framework Ionic. Espera-se que esse aplicativo contribua para a eficácia do tratamento e convívio com indivíduos autistas, simplificando a comunicação entre as partes envolvidas.
Rumo a um Modelo Conceitual para Governança de Sistemas-de-Sistemas
Authors: Morais Edison A. M. , França Andrey G. , Graciano-Neto Valdemar V.
Published: June 2024

Sistemas-de-Sistemas (SoS) são sistemas complexos e distribuídos. Essa complexidade demanda práticas de governança para garantir o alinhamento estratégico e a eficiência operacional do SoS com as empresas envolvidos. Neste sentido, a principal contribuição deste artigo é a apresentação de um modelo conceitual de Governança de SoS desenvolvido por meio de Grounded Theory (GT). Como resultado, é apresentado um modelo conceitual que pode servir como referência para estudos posteriores, além de capturar o estado da arte e auxiliar na instanciação de SoS com governança em cenários reais.
Exploring the Function of Inflammatory Routes in Insulin Resistance: Interpreting the Inflammatory Veil of Medusa
Authors: Kumari Anchala
Published: June 2024

A common component of metabolic diseases including metabolic syndrome and type 2 diabetes, insulin resistance is now known to be closely linked to persistent low-grade inflammation. This chapter explores the intricate connection between insulin resistance and inflammatory pathways, clarifying the molecular processes that underlie inflammation-induced insulin resistance. We examine the part that important inflammatory mediators play in upsetting insulin signalling pathways and encouraging insulin resistance, including cytokines, chemokines, and adipokines. We also go over how inflammatory signalling cascades, like the JNK and NF-κB pathways, affect insulin sensitivity and cellular metabolism. Understanding the interaction between insulin resistance and inflammation can help to better understand the pathogenesis of metabolic diseases and identify possible treatment targets. In people who are at risk of developing issues associated with insulin resistance, strategies targeted at reducing inflammatory responses may be able to reduce insulin resistance and enhance metabolic health.
Perspective Chapter: Sustainability and Media Influence – The Role of Global Media in Creating a New Environmental Culture
Authors: Valkanova Vesselina , Mihailov Nikolai
Published: June 2024

Media in today’s world, particularly those that disseminate information through digital platforms, are one of the most influential sources of impact on people and society. The chapter is an attempt to review some basic points about the role of media—traditional and digital—in creating a new environmental culture within the context of the environment and environmental crisis. The chapter explores issues about the origin and development of environmental crisis as cultural phenomena, as well as some ideas about the moral assessment of media influence in informing, presenting and forming a position toward the problems of the environment. The concept of sustainability is changing both its content and its ground, becoming associated not only with the development of the natural and social environment, but also with attempts to build a new environmental culture. The role of the global media is to inform and motivate all members of society, especially young people for sustainability. More important conclusions are that media, ethics, and environmental knowledge must be developed in cooperation in order to explain and form specific moral consciousness, a new type of culture that does not allow indifference to the environment.