bluuebunny/crossref_metadata_2025 huggingface dataset:
The relationship between mindfulness and objective measures of body awareness: A meta-analysis
Authors: Treves Isaac N. , Tello Lawrence Y. , Davidson Richard J. , Goldberg Simon B.
Published: November 2019

Although awareness of bodily sensations is a common mindfulness meditation technique, studies assessing the relationship between mindfulness and body awareness have provided mixed results. The current study sought to meta-analytically examine the relationship between mindfulness operationalized as a dispositional trait or a construct trained through short- (i.e., randomized controlled trials [RCTs]) or long-term mindfulness meditation practice with objective measures of body awareness accuracy. PubMed, Web of Science, PsycINFO, and Scopus were searched. Studies were eligible if they reported the association between mindfulness and body awareness, were published in English, and included adults. Across 15 studies (17 independent samples), a small effect was found linking mindfulness with greater body awareness accuracy (g = 0.21 [0.08, 0.34], N = 879). When separated by study design, only RCTs continued to show a significant relationship (g = 0.20, [0.02, 0.38], k = 7, n = 505). Heterogeneity of effects was low (I2 < 25%), although with wide confidence intervals. Effects were not moderated by study quality. Low fail-safe N estimates reduce confidence in the observed effects. Results suggest a small but potentially detectable relationship between mindfulness and body awareness accuracy. Future investigations could examine individual differences in body awareness as a mechanism within mindfulness interventions.
Electrochemical detection of different p53 conformations by using nanostructured surfaces
Authors: Tonello Sarah , Stradolini Francesca , Abate Giulia , Uberti Daniela , Serpelloni Mauro , Carrara Sandro , Sardini Emilio
Published: November 2019

Protein electrochemistry represents a powerful technique for investigating the function and structure of proteins. Currently available biochemical assays provide limited information related to the conformational state of proteins and high costs. This work provides novel insights into the electrochemical investigation of the metalloprotein p53 and its redox products using label-free direct electrochemistry and label-based antibody-specific approaches. First, the redox activities of different p53 redox products were qualitatively investigated on carbon-based electrodes. Then, focusing on the open p53 isoform (denatured p53), a quantitative analysis was performed, comparing the performances of different bulk and nanostructured materials (carbon and platinum). Overall, four different p53 products could be successfully discriminated, from wild type to denatured. Label-free analysis suggested a single electron exchange with electron transfer rate constants on the order of 1 s−1. Label-based analysis showed decreasing affinity of pAb240 towards denatured, oxidized and nitrated p53. Furthermore, platinum nanostructured electrodes showed the highest enhancement of the limit of detection in the quantitative analysis (100 ng/ml). Overall, the obtained results represent a first step towards the implementation of highly requested complex integrated devices for clinical practices, with the aim to go beyond simple protein quantification.
Fabrication of Second Generation Smarter PLGA Based Nanocrystal Carriers for Improvement of Drug Delivery and Therapeutic Efficacy of Gliclazide in Type-2 Diabetes Rat Model
Authors: Panda Bibhu Prasad , Krishnamoorthy Rachna , Bhattamisra Subrat Kumar , Shivashekaregowda Naveen Kumar Hawala , Seng Low Bin , Patnaik Sujata
Published: November 2019

Drug delivery and therapeutic challenges of gliclazide, a BCS class II drug used in type 2 diabetes mellitus (T2DM) can be overcome by exploring smarter carriers of second-generation nanocrystals (SGNCs). A combined method of emulsion diffusion, high-pressure homogenization and solvent evaporation method were employed in the preparation of gliclazide loaded poly (D, L-lactide-co-glycolide) (PLGA) SGNCs. Taguchi experimental design was adopted in fabrication of Gliclazide SGNc using Gliclazide -PLGA ratio at 1:0.5, 1:0.75, 1:1 with stabilizer (Poloxamer-188, PEG 4000, HPMC E15 at 0.5, 0.75, 1% w/v). The formulated gliclazide of SGNCs were investigated for physicochemical properties, in vitro drug release, and in vivo performance studies using type-2 diabetes rat model. The formulation (SGNCF1) with Drug: PLGA 1: 0.5 ratio with 0.5% w/v Poloxamer-188 produced optimized gliclazide SGNCs. SGNCF1 showed spherical shape, small particle size (106.3 ± 2.69 nm), good zeta potential (−18.2 ± 1.30 mV), small PDI (0.222 ± 0.104) and high entrapment efficiency (86.27 ± 0.222%). The solubility, dissolution rate and bioavailability of gliclazide SGNCs were significantly improved compared to pure gliclazide. The findings emphasize gliclazide SGNCs produce faster release initially, followed by delayed release with improved bioavailability, facilitate efficient delivery of gliclazide in T2DM with better therapeutic effect.
An Escherichia coli ST131 pangenome atlas reveals population structure and evolution across 4,071 isolates
Authors: Decano Arun Gonzales , Downing Tim
Published: November 2019

Escherichia coli ST131 is a major cause of infection with extensive antimicrobial resistance (AMR) facilitated by widespread beta-lactam antibiotic use. This drug pressure has driven extended-spectrum beta-lactamase (ESBL) gene acquisition and evolution in pathogens, so a clearer resolution of ST131’s origin, adaptation and spread is essential. E. coli ST131’s ESBL genes are typically embedded in mobile genetic elements (MGEs) that aid transfer to new plasmid or chromosomal locations, which are mobilised further by plasmid conjugation and recombination, resulting in a flexible ESBL, MGE and plasmid composition with a conserved core genome. We used population genomics to trace the evolution of AMR in ST131 more precisely by extracting all available high-quality Illumina HiSeq read libraries to investigate 4,071 globally-sourced genomes, the largest ST131 collection examined so far. We applied rigorous quality-control, genome de novo assembly and ESBL gene screening to resolve ST131’s population structure across three genetically distinct Clades (A, B, C) and abundant subclades from the dominant Clade C. We reconstructed their evolutionary relationships across the core and accessory genomes using published reference genomes, long read assemblies and k-mer-based methods to contextualise pangenome diversity. The three main C subclades have co-circulated globally at relatively stable frequencies over time, suggesting attaining an equilibrium after their origin and initial rapid spread. This contrasted with their ESBL genes, which had stronger patterns across time, geography and subclade, and were located at distinct locations across the chromosomes and plasmids between isolates. Within the three C subclades, the core and accessory genome diversity levels were not correlated due to plasmid and MGE activity, unlike patterns between the three main clades, A, B and C. This population genomic study highlights the dynamic nature of the accessory genomes in ST131, suggesting that surveillance should anticipate genetically variable outbreaks with broader antibiotic resistance levels. Our findings emphasise the potential of evolutionary pangenomics to improve our understanding of AMR gene transfer, adaptation and transmission to discover accessory genome changes linked to novel subtypes.
Spatiotemporal characteristics of an attacker’s strategy to pass a defender effectively in a computer-based one-on-one task
Authors: Tsutsui Kazushi , Shinya Masahiro , Kudo Kazutoshi
Published: November 2019

For modern humans, chase-and-escape behaviors are fundamental skills in many sports. A critical factor related to the success or failure of chase-and-escape is the visuomotor delay. Recent studies on sensorimotor decision making have shown that humans can incorporate their own visuomotor delay into their decisions. However, the relationship between the decision of an attacker and the visuomotor delay of a defender is still unknown. Here, we conducted a one-on-one chase-and-escape task for humans and investigated the characteristics of the direction changes of the attacker and the responses of the defender. Our results showed that the direction change of the attacker has two characteristics: uniformity of spatial distribution and bimodality of temporal distribution. In addition, we showed that the response of the defender did not depend on the position but it was delayed to the direction change of the attacker with a short interval. These results suggest that the characteristics of direction change of an attacker increased unpredictability, and it could be useful for preventing the predictive response of the defender and to receive the benefit of an extra response delay of tens of milliseconds, respectively.
Diagnostic Test Efficacy of Meibomian Gland Morphology and Function
Authors: Xiao Jiaxin , Adil Muhammed Yasin , Olafsson Jonatan , Chen Xiangjun , Utheim Øygunn A. , Ræder Sten , Lagali Neil S. , Dartt Darlene A. , Utheim Tor P.
Published: November 2019

Meibomian gland dysfunction (MGD) is the leading cause of dry eye and proposed treatments are based on disease severity. Our purpose was to establish reliable morphologic measurements of meibomian glands for evaluating MGD severity. This retrospective, cross-sectional study included 100 MGD patients and 20 controls. The patients were classified into dry eye severity level (DESL) 1–4 based on symptoms and clinical parameters including tear-film breakup time, ocular staining and Schirmer I. The gland loss, length, thickness, density and distortion were analyzed. We compared the morphology between patients and controls; examined their correlations to meibum expressibility, quality, and DESL. Relative to controls, the gland thickness, density and distortion were elevated in patients (p < 0.001 for all tests). The area under the receiver operating characteristic curve was 0.98 (95% confidence interval [CI], 0.96–1.0) for gland loss, and 0.96 (CI 0.91–1.0) for gland distortion, with a cutoff value of six distorted glands yielding a sensitivity of 93% and specificity of 97% for MGD diagnosis. The gland distortion was negatively correlated to the meibum expressibility (r = −0.53; p < 0.001) and DESL (r = −0.22, p = 0.018). In conclusion, evaluation of meibomian gland loss and distortion are valuable complementary clinical parameters to assess MGD status.
Cerebrospinal fluid growth-associated protein 43 in multiple sclerosis
Authors: Sandelius Åsa , Sandgren Sofia , Axelsson Markus , Malmeström Clas , Novakova Lenka , Kostanjevecki Vesna , Vandijck Manu , Blennow Kaj , Zetterberg Henrik , Lycke Jan
Published: November 2019

Neurodegeneration in multiple sclerosis (MS) correlates with disease progression and reparative processes may be triggered. Growth-associated protein 43 (GAP-43) exhibits induced expression during axonal growth and reduced expression during MS progression. We aimed to evaluate if GAP-43 can serve as a biomarker of regeneration in relapsing-remitting MS (RRMS) and whether disease-modifying therapies (DMTs) influence GAP-43 concentration in cerebrospinal fluid (CSF). GAP-43 was measured using an enzyme-linked immunosorbent assay in 105 MS patients (73 RRMS, 12 primary progressive MS, 20 secondary progressive MS) and 23 healthy controls (HCs). In 35 of the patients, lumbar puncture, clinical assessment, and magnetic resonance imaging was performed before initiation of therapeutic intervention, and at follow-up. CSF GAP-43 concentration was significantly lower in progressive MS compared with HCs (p = 0.004) and RRMS (p =  < 0.001) and correlated negatively with disability (p = 0.026). However, DMTs did not alter CSF GAP-43. Interestingly, in RRMS CSF GAP-43 levels were higher in patients with signs of active inflammatory disease than in patients in remission (p = 0.042). According to CSF GAP-43 concentrations, regeneration seems reduced in progressive MS, increased during disease activity in RRMS but is unaffected by treatment of highly active DMTs.
Publisher Correction: Assessing the role of Rv1222 (RseA) as an anti-sigma factor of the Mycobacterium tuberculosis extracytoplasmic sigma factor SigE
Authors: Boldrin Francesca , Cioetto Mazzabò Laura , Anoosheh Saber , Palù Giorgio , Gaudreau Luc , Manganelli Riccardo , Provvedi Roberta
Published: November 2019

An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Resonant and non-resonant femtosecond ionization mass spectrometry of organochlorine pesticides
Authors: Madunil Siddihalu Lakshitha , Imasaka Totaro , Imasaka Tomoko
Published: November 2019

The ionization mechanism was studied based on resonance-enhanced two-photon ionization and non-resonant two- and three-photon ionizations.
A new long-wavelength fluorescent probe for tracking peroxynitrite in live cells and inflammatory sites of zebrafish
Authors: Wang Guanyang , Wang Yang , Wang Chengcheng , Huang Chusen , Jia Nengqin
Published: November 2019

Design of a long-wavelength fluorescent probe for tracking peroxynitrite in live cells and inflammatory sites of zebrafish.
A novel colorimetric and far-red emission ratiometric fluorescent probe for the highly selective and ultrafast detection of hypochlorite in water and its application in bioimaging
Authors: Zhang Yuanyuan , Ma Yufan , Wang Zhuo , Zhang Xueyan , Chen Xin , Hou Shicong , Wang Hongmei
Published: November 2019

Hypochlorous acid (HOCl)/hypochlorite (OCl−), an important reactive oxygen species, plays a number of important roles in various physiological processes.
Red phosphorus decorated graphene oxide nanosheets: label-free DNA detection
Authors: Mandal Tapas Kumar , Lee Yong Rok , Parvin Nargish
Published: November 2019

f-RP@N-rGO NSs are promising structures for the selective sensing of target DNA molecules through a highly rapid response in fluorescence intensity toward single and double stranded DNA without the need of any fluorescent tags.
Hybrid organic–inorganic mononuclear lanthanoid single ion magnets
Authors: Cañón-Mancisidor Walter , Zapata-Lizama Matias , Hermosilla-Ibáñez Patricio , Cruz Carlos , Venegas-Yazigi Diego , Mínguez Espallargas Guillermo
Published: November 2019

The plasticity of the coordination chemistry of lanthanoid ions has allowed the design and synthesis for the first time of a family of mononuclear hybrid organic–inorganic lanthanoid complexes with slow relaxation of the magnetization.
Ruthenium porphyrin catalysed intermolecular amino-oxyarylation of alkenes to give primary aminesviaa ruthenium nitrido intermediate
Authors: Yu Daohong , Shing Ka-Pan , Liu Yungen , Liu Haiyang , Che Chi-Ming
Published: November 2019

Ruthenium porphyrin catalysed intermolecular amino-oxyarylation of alkenes with DPH to give primary amines was achieved in moderate to good yields.
In vivo biosynthesis of tyrosine analogs and their concurrent incorporation into a residue-specific manner for enzyme engineering
Authors: Won Yumi , Jeon Hyunwoo , Pagar Amol D. , Patil Mahesh D. , Nadarajan Saravanan Prabhu , Flood Dillon T. , Dawson Philip E. , Yun Hyungdon
Published: November 2019

A cellular system for the in vivo biosynthesis of Tyr-analogs and their concurrent incorporation into target proteins is reported.
Triphenylphosphine-assisted dehydroxylative Csp3–N bond formation via electrochemical oxidation
Authors: Xu Zhimin , Zheng Yue , Wang Zhihui , Shao Xiaoqing , Tian Lifang , Wang Yahui
Published: November 2019

A dehydroxylative Csp3–N coupling by electrochemical oxidation with readily available alcohols as substrates and a wide variety of azoles and amides as N-nucleophiles.
Coordination polymers with salicylaldehyde ligands: structural diversity, selective sorption and luminescence sensing properties
Authors: Liu Yi , Zhao Yue , Liu Zhi-Qiang , Liu Xiao-Hui , Zhang Xiu-Du , Sun Wei-Yin
Published: November 2019

Five new coordination polymers with salicylaldehyde ligands were obtained. They show diverse structures, selective dye adsorption and fluorescence sensing properties.
Correction: Facile hydrothermal synthesis of hierarchical porous priceite (Ca4B10O19·7H2O) microspheres as high-efficiency adsorbents for heavy metal ions removal
Authors: Zhu Wancheng , Chen Xiuping , Sun Panpan , Li Jie , Zhai Peiyan , Zheng Yuyu , Wang Lihua , Zhang Heng , Zhang Zhaoshun
Published: November 2019

Correction for ‘Facile hydrothermal synthesis of hierarchical porous priceite (Ca4B10O19·7H2O) microspheres as high-efficiency adsorbents for heavy metal ions removal’ by Wancheng Zhu et al., CrystEngComm, 2019, DOI: 10.1039/c9ce01003c.
Triplet state structure–property relationships in a series of platinum acetylides: effect of chromophore length and end cap electronic properties
Authors: Cooper Thomas M. , Haley Joy E. , Krein Douglas M. , Burke Aaron R. , Stewart David J. , Fore Jennifer L. , Slagle Jonathan E.
Published: November 2019

Ligand end cap X determines triplet state behavior.
Understanding deep dehydrogenation and cracking of n-butane on Ni(111) by a DFT study
Authors: Wu Chan , Wang Li , Xiao Zhourong , Li Guozhu , Wang Lichang
Published: November 2019

A DFT study on deep dehydrogenation and cracking of long-chain hydrocarbon involving the cleavage of different C–C bonds on nickel.
Micro-solvation of CO in water: infrared spectra and structural calculations for (D2O)2–CO and (D2O)3–CO
Authors: Barclay A. J. , Pietropolli Charmet A. , Michaelian K. H. , McKellar A. R. W. , Moazzen-Ahmadi N.
Published: November 2019

The weakly-bound molecular clusters (D2O)2–CO and (D2O)3–CO are observed in the C–O stretch fundamental region (≈2150 cm−1), and their rotationally-resolved infrared spectra yield precise rotational parameters.
Emerging aqueous two-phase systems: from fundamentals of interfaces to biomedical applications
Authors: Chao Youchuang , Shum Ho Cheung
Published: November 2019

This review summarizes recent advances of aqueous two-phase systems (ATPSs), particularly their interfaces, with a focus on biomedical applications.
Macrocyclic multinuclear metal complexes acting as catalysts for organic synthesis
Authors: Nath Bikash Dev , Takaishi Kazuto , Ema Tadashi
Published: November 2019

Recent progress in homogeneous catalysis with macrocyclic multinuclear metal complexes (categories A–C) is overviewed.
Base-controlled product switch in the ruthenium-catalyzed protodecarbonylation of phthalimides: a mechanistic study
Authors: D'Alterio Massimo Christian , Yuan Yu-Chao , Bruneau Christian , Talarico Giovanni , Gramage-Doria Rafael , Poater Albert
Published: November 2019

Mechanism of the ruthenium-catalyzed protodecarbonylation of phthalimides into benzamides elucidated by experiments and calculations: the various roles of the bases responsible for the control of chemoselectivity.
Spatially resolved NMR spectroscopy of heterogeneous gas phase hydrogenation of 1,3-butadiene with parahydrogen
Authors: Svyatova Alexandra , Kononenko Elizaveta S. , Kovtunov Kirill V. , Lebedev Dmitry , Gerasimov Evgeniy Yu. , Bukhtiyarov Andrey V. , Prosvirin Igor P. , Bukhtiyarov Valerii I. , Müller Christoph R. , Fedorov Alexey , Koptyug Igor V.
Published: November 2019

Glass tube reactors with Pd, Pt, Rh or Ir nanoparticles dispersed on a thin layer of TiO2, CeO2, SiO2 or Al2O3 provided mechanistic insight into the hydrogenation of 1,3-butadiene using parahydrogen.
Tandem deoxygenative hydrosilation of carbon dioxide with a cationic scandium hydridoborate and B(C6F5)3
Authors: Beh Daniel W. , Piers Warren E. , Gelfand Benjamin S. , Lin Jian-Bin
Published: November 2019

A scandium hydridoborate complex supported by the dianionic pentadentate ligand B2Pz4Py is prepared via hydride abstraction from the previously reported scandium hydride complex with tris-pentafluorophenyl borane.
Emerging investigator series: locally enhanced electric field treatment (LEEFT) with nanowire-modified electrodes for water disinfection in pipes
Authors: Zhou Jianfeng , Wang Ting , Chen Wensi , Lin Beichen , Xie Xing
Published: November 2019

Assisted by perpendicularly-grown nanowires, a coaxial-electrode locally enhanced electric field treatment (LEEFT) device achieves high disinfection in pipes.
Photoredox-catalyzed biomass intermediate conversion integrated with H2 production over Ti3C2Tx/CdS composites
Authors: Li Yue-Hua , Zhang Fan , Chen Yan , Li Jing-Yu , Xu Yi-Jun
Published: November 2019

Ti3C2Tx MXene/CdS composites are employed in the aqueous-phase photoredox conversion of furfural alcohol to furfural and hydrogen.
Atomic spectrometry update – a review of advances in environmental analysis
Authors: Bacon Jeffrey R. , Butler Owen T. , Cairns Warren R. L. , Cook Jennifer M. , Davidson Christine M. , Cavoura Olga , Mertz-Kraus Regina
Published: November 2019

This review covers advances in the analysis of air, water, plants, soils and geological materials by a range of atomic spectrometric techniques including atomic emission, absorption, fluorescence and mass spectrometry.
Development and evaluation of inexpensive automated deep learning-based imaging systems for embryology
Authors: Kanakasabapathy Manoj Kumar , Thirumalaraju Prudhvi , Bormann Charles L. , Kandula Hemanth , Dimitriadis Irene , Souter Irene , Yogesh Vinish , Kota Sai Pavan Sandeep , Yarravarapu Divyank , Gupta Raghav , Pooniwala Rohan , Shafiee Hadi
Published: November 2019

Artificial intelligence enabled inexpensive imaging hardware can be a valuable tool for reliable embryo assessments in in vitro fertilization.
Regioselective thiocyanation of corroles and the synthesis of gold nanoparticle–corrole assemblies
Authors: Sahu Kasturi , Mondal Sruti , Patra Bratati , Pain Tanmoy , Patra Sajal Kumar , Dosche Carsten , Kar Sanjib
Published: November 2019

The newly synthesized bis(thiocyanato)-triphenylcorrole has turned out to be a good corrole based precursor for the facile synthesis of thiol protected gold nanoparticles (Au NPs).
Layered double hydroxides intercalated with borate: effect of fertilization on boron leaching and successive sunflower cultivations
Authors: Castro Gustavo Franco de , Ferreira Jader Alves , Zotarelli Lincoln , Mattiello Edson Marcio , Novais Roberto Ferreira , Tronto Jairo
Published: November 2019

Layered double hydroxides intercalated with borate: reduction of boron leaching in sandy soil and increase in plant boron uptake.
Biologically active marine natural products and their molecular targets discovered using a chemical genetics approach
Authors: Williams David E. , Andersen Raymond J.
Published: November 2019

This review presents examples that illustrate the effectiveness of using a chemical genetics approach for the discovery of biologically active marine natural products and their molecular targets.
Correlation between in situ structural and optical characterization of the semiconductor-to-metal phase transition of VO2 thin films on sapphire
Authors: Cesca Tiziana , Scian Carlo , Petronijevic Emilija , Leahu Grigore , Li Voti Roberto , Cesarini Gianmario , Macaluso Roberto , Mosca Mauro , Sibilia Concita , Mattei Giovanni
Published: November 2019

In situ XRD and IR optical measurements demonstrate the coexistence of M1 and R phases during the SMT transition of VO2 thin films.
Photoaffinity probes for nematode pheromone receptor identification
Authors: Zhang Ying K. , Reilly Douglas K. , Yu Jingfang , Srinivasan Jagan , Schroeder Frank C.
Published: November 2019

Identification of pheromone receptors plays a central role for uncovering signaling pathways that underlie chemical communication in animals.
Synthesis and characterization of segmented poly(ester-urethane)s (PEUs) containing carotenoids
Authors: Rodríguez-deLeón Eloy , Bah Moustapha , Jiménez-Halla J. Oscar C. , Bonilla-Cruz José , Estévez Miriam , Báez José E.
Published: November 2019

A series of three different xanthophylls such as lutein, zeaxanthin, and astaxanthin were used as chain extender agents in the synthesis of a new family of segmented poly(ester-urethane)s (PEUs) derived from poly(ε-caprolactone) (PCL).
Stable surface functionalization of carbonized mesoporous silicon
Authors: Riikonen Joakim , Nissinen Tuomo , Alanne Aino , Thapa Rinez , Fioux Philippe , Bonne Magali , Rigolet Séverinne , Morlet-Savary Fabrice , Aussenac Fabien , Marichal Claire , Lalevée Jacques , Vepsäläinen Jouko , Lebeau Bénédicte , Lehto Vesa-Pekka
Published: November 2019

A new method to produce functional surfaces on porous silicon allow long term use of the material in aqueous environments.
Sea urchin-like CuCo2S4 microspheres with a controllable interior structure as advanced electrode materials for high-performance supercapacitors
Authors: Jia Henan , Cai Yifei , Wang Zhaoyue , Zheng Xiaohang , Li Chun , Liang Haoyan , Qi Junlei , Cao Jian , Feng Jicai , Fei Weidong
Published: November 2019

The rational construction of a supercapacitor electrode structure can realize high specific surface area, good cycling stability and high capacitance.
Incorporation of narcissistic self-sorting supramolecular interactions for the spontaneous fabrication of multiple-color solid-state materials for OLED applications
Authors: Tsai Yu-Tang , Raffy Guillaume , Liu Hsiang-Fang , Peng Bo-Ji , Tseng Kuo-Pi , Hirsch Lionel , Del Guerzo André , Bassani Dario M. , Wong Ken-Tsung
Published: November 2019

A hat trick makes vesicles self-sort into their color families!
Rhodium-catalyzed homodimerization–cyclization reaction of two vinyl isocyanides: a general route to 2-(isoquinolin-1-yl)oxazoles
Authors: Wang Zhuo , Meng Xiang-He , Liu Pei , Hu Wan-Ying , Zhao Yu-Long
Published: November 2019

A novel rhodium-catalyzed homodimerization–cyclization reaction of two vinyl isocyanides has been developed for the synthesis of 2-(isoquinolin-1-yl)oxazoles by formation of three new bonds and two rings in a single step.
Recent advances in the synthesis of indoles from alkynes and nitrogen sources
Authors: Neto José Sebastião Santos , Zeni Gilson
Published: November 2019

This review highlights ten years of success in the synthesis of indoles using alkynes and nitrogen sources as substrates.
Facile one-pot synthesis of NiCo2Se4-rGO on Ni foam for high performance hybrid supercapacitors
Authors: Amin Bahareh Golrokh , Masud Jahangir , Nath Manashi
Published: November 2019

A hybrid supercapacitor comprising a NiCo2Se4-rGO composite has been fabricated on Ni foam and shows high energy and power density and superior flexibility.
Resonant waveguide grating based assays for colloidal aggregate detection and promiscuity characterization in natural products
Authors: Wang Rong , Wang Jixia , Liu Yanfang , Zhang Xiuli , Liang Xinmiao
Published: November 2019

Resonant waveguide grating based assays to eliminate colloidal aggregate induced false activity involving natural products.
GPI0363 inhibits the interaction of RNA polymerase with DNA inStaphylococcus aureus
Authors: Paudel Atmika , Panthee Suresh , Hamamoto Hiroshi , Sekimizu Kazuhisa
Published: November 2019

GPI0363 has a distinct mode of actionviaSigA and is active against bacteria resistant to clinically used RNAP inhibitors.
Competing magnetic effects due to the incorporation of oxygen in thin films of (ZnCo)O
Authors: Saeedi Ahmad M. A. , Gerriu Fatma M. , Ying Minju , Alshammari Marzook S. , Heald Steve M. , Li Xiaoli , Blythe Harry J. , Fox A. Mark , Gehring Gillian A.
Published: November 2019

The properties of laser ablated films of ZnCoO depend on the cobalt precursor used to make the target.
Preparation and microwave absorption performance of a flexible Fe3O4/nanocarbon hybrid buckypaper and its application in composite materials
Authors: Wang Jia , Jiao Jian , Sun Guangmei , Yuan Kai , Guan Ziyi , Wei Xinyi
Published: November 2019

Flexible nanofilms are used as wave absorbing coatings for fiber/epoxy matrix to prepare lightweight wave-absorbing composites.
Facile synthesis of perovskite CeMnO3 nanofibers as an anode material for high performance lithium-ion batteries
Authors: Yue Bin , Hu Quanli , Ji Lei , Wang Yin , Liu Jinghai
Published: November 2019

A facile synthesis of perovskite-type CeMnO3 nanofibers as a high performance anode material for lithium-ion batteries was demonstrated.
Thermal and structural properties, and molecular dynamics in organic–inorganic hybrid perovskite (C2H5NH3)2ZnCl4
Authors: Lim Ae Ran
Published: November 2019

The thermal and structural properties and molecular dynamics of layered perovskite-type (C2H5NH3)2ZnCl4 are investigated by DSC, TGA, and MAS NMR spectroscopy.
Optical characteristics of GaAs/GaAsSb/GaAs coaxial single quantum-well nanowires with different Sb components
Authors: Li Haolin , Tang Jilong , Pang Guotao , Wang Dengkui , Fang Xuan , Chen Rui , Wei Zhipeng
Published: November 2019

GaAs/GaAs1−xSbx/GaAs coaxial single quantum-well nanowires with larger Sb content result in better electron confinement, which greatly improves their thermal stability.
A complete picture of protein unfolding and refolding in surfactants
Authors: Pedersen Jannik Nedergaard , Lyngsø Jeppe , Zinn Thomas , Otzen Daniel E. , Pedersen Jan Skov
Published: November 2019

The time-resolved study reveals several transition states during SDS-induced unfolding of the protein, as well as under refolding of the protein by the nonionic surfactant C12E8.
Ni loaded on N-doped carbon encapsulated tungsten oxide nanowires as an alkaline-stable electrocatalyst for water reduction
Authors: Lv Cuncai , Yan Guoying , Wang Xiaobo , Gao Linjie , Xu Shichen , San Xingyuan , Wang Shufang , Li Yaguang , Huang Zhipeng
Published: November 2019

A hierarchical electrocatalyst, Ni on N-doped carbon shell coated oxygen-vacancy-rich WOx nanowires, exhibits excellent stability and superb alkaline HER activity.
A lattice kinetic Monte-Carlo method for simulating chromosomal dynamics and other (non-)equilibrium bio-assemblies
Authors: Miermans Christiaan A. , Broedersz Chase P.
Published: November 2019

Demonstration of ingredients, advantages, and pitfalls of a lattice kinetic Monte-Carlo approach to simulate DNA organization by loop-extrusion factors.
3D lithiophilic–lithiophobic–lithiophilic dual-gradient porous skeleton for highly stable lithium metal anode
Authors: Zheng Hongfei , Zhang Qingfei , Chen Qiulin , Xu Wanjie , Xie Qingshui , Cai Yuxin , Ma Yating , Qiao Zhensong , Luo Qing , Lin Jie , Wang Laisen , Qu Baihua , Sa Baisheng , Peng Dong-Liang
Published: November 2019

A 3D porous lithiophilic–lithiophobic–lithiophilic dual-gradient CAZPZ current collector is designed to regulate homogeneous Li deposition, and the CAZPZ–Li hybrid anode has superb practical applications in different full cells.
Novel MoSi2 catalysts featuring surface activation as highly efficient cathode materials for long-life Li–O2 batteries
Authors: Dang Congcong , Wang Yu , He Biao , Zhang Weibin , Dang Feng , Wang Hongchao , Du Yong
Published: November 2019

The surface conditions of MoSi2 particles and the stable crystal structure contribute to the great electrochemical performance of Li–O2 batteries.
Employing a T-shirt template and variant of Schweizer's reagent for constructing a low-weight, flexible, hierarchically porous and textile-structured copper current collector for dendrite-suppressed Li metal
Authors: Zhu Ruijie , Sheng Nan , Rao Zhonghao , Zhu Chunyu , Aoki Yoshitaka , Habazaki Hiroki
Published: November 2019

A low-weight and flexible T-shirt structured porous Cu current collector with superior performance for Li metal anodes was fabricated and could suppress Li dendrite growth.
In situ engineered ZnS–FeS heterostructures in N-doped carbon nanocages accelerating polysulfide redox kinetics for lithium sulfur batteries
Authors: Li Wenda , Gong Zhijiang , Yan Xiujuan , Wang Dezhu , Liu Jing , Guo Xiaosong , Zhang Zhonghua , Li Guicun
Published: November 2019

Building heterostructures containing dissimilar coupling components with different bandgaps can promote interfacial reaction kinetics and accelerate charge carrier transport for Li–S batteries.
Liquid–liquid extraction: a universal method to synthesize liquid colloidal photonic crystals
Authors: Wang Chuan , Zhang Xin , Zhu Huimin , Fu Qianqian , Ge Jianping
Published: November 2019

A liquid–liquid extraction method is developed to produce liquid PCs at room temperature. The colloidal particles precipitate to form liquid PCs due to the extraction of solvent and the supersaturation of particles.
Differential expression of ghrelin and GHSR via the mTOR pathway during the dynamic carcinogenic process involving oral, potentially malignant disorders
Authors: Lou Jianing , Liu Lin , Zhang Weizhen , Zhou Zengtong , Fan Yuan
Published: November 2019

The purpose was to explore the sequence changes in ghrelin and GHSR in the mTOR signaling pathway during carcinogenesis involving oral, potentially malignant disorders (OPMD). The samples were confirmed through in vivo pathologic tissue screening and diagnosis. The immunohistochemical method was used to detect the expression of the ghrelin/growth hormone secretagogue receptor (GHSR) protein. The expression of ghrelin, GHSR 1α, GHSR 1β, and mammalian target of rapamycin (mTOR) RNA were detected by real-time PCR. The expression of ghrelin, GHSR, mTOR, and phosphorylated mTOR (phosphor-mTOR) protein were detected by Western blot. The expression of ghrelin/GHSR increased gradually in the dynamic process of OPMD carcinogenesis. There was a correlation between the increase in ghrelin, GHSR, mTOR, and phospho-mTOR. The in vivo expression of ghrelin/GHSR protein was the most apparent pathologic change from normal-to-mild, moderate, and severe dysplasia, and finally to the dynamic process from normal-to-mild-to-moderate dysplasia. The in vitro cell experiments based on QPCR results also proved that GHSR 1a functional receptor of ghrelin had a peak expression in LEUK-1 cells. In conclusioin, the close relationship between ghrelin and OPMD carcinogenesis can be used as a new biological target to assess the carcinogenesis of OPMD.
Sentence Repetition: A Clinical Marker for Developmental Language Disorder in Danish
Authors: Vang Christensen Rikke
Published: November 2019

Purpose

The aim of the study was to explore the potential of performance on a Danish sentence repetition (SR) task—including specific morphological and syntactic properties—to identify difficulties in children with developmental language disorder (DLD) relative to typically developing (TD) children. Furthermore, the potential of the task as a clinical marker for Danish DLD was explored.

Method

SR performance of children with DLD aged 5;10–14;1 (years;months;
n
= 27) and TD children aged 5;3–13;4 (
n
= 87) was investigated.

Results

Compared to TD same-age peers, children with DLD were less likely to repeat the sentences accurately but more likely to make ungrammatical errors with respect to verb inflection and use of determiners and personal pronouns. Younger children with DLD also produced more word order errors that their TD peers. Furthermore, older children with DLD performed less accurately than younger TD peers, indicating that the SR task taps into morphosyntactic areas of particular difficulty for Danish children with DLD. The classification accuracy associated with SR performance showed high levels of sensitivity and specificity (> 90%) and likelihood ratios indicating good identification potential for clinical and future research purposes.

Conclusion

SR performance has a strong potential for identifying children with DLD, also in Danish, and with a carefully designed SR task, performance has potential for revealing morphosyntactic difficulties.

Supplemental Material

https://doi.org/10.23641/asha.10314437
Broadband power amplifier using hairpin bandpass filter matching network
Authors: Haider Muhammad Furqan , You Fei , Shi Weimin , Ahmad Shakeel , Qi Tian
Published: November 2019

This Letter presents a new combination of a broadband power amplifier (PA) and an output microstrip hairpin bandpass filter. The filter is designed based on the fifth‐order Chebyshev low‐pass prototype element values. Even–odd mode impedance analysis is used to calculate the filter parameters. Meanwhile, only the fundamental impedance matching is considered for this design. Therefore, a highly selective bandpass response is obtained to provide a spurious‐free fundamental impedance matching. For verification, a broadband PA‐filter component across 1.9–3.1 GHz (48%) is designed and fabricated. Measurements have shown a drain efficiency of 48–56.6% with 39.3–40.5 dBm of maximum output power.
Commercial graphene nanoplatelets‐based tunable attenuator
Authors: Yasir M. , Savi P.
Published: November 2019

A commercial graphene nanoplatelets‐based tunable attenuator is proposed. The attenuator comprises of a couple of microstrip lines connected through a gap where the commercial graphene nanoplatelets are drop casted. The transmitted signal through the microstrip line can be varied by an applied DC bias voltage that alters the graphene resistance. The DC resistance of commercially acquired graphene is higher than lab‐grown graphene and so is the resulting minimum attenuation of the transmitted signal. The proposed structure is designed to reduce both the minimum graphene resistance and the transmission. The resultant dynamic range of attenuation is more than twice as compared to other series attenuators designed with lab grown graphene nanoplatelets. The operating frequency of the attenuator is from 1 to 5 GHz with maximum dynamic range of attenuation almost 10 dB.
Composite control of fuel quantity actuator system for diesel engines via backstepping control technique and generalised proportional integral observer
Authors: Sun Hao , Dai Chen , Li Shihua
Published: November 2019

In an electronically controlled VE distributive pump, the fuel quantity actuator (FQA) is a significant component. It is responsible for governing the quantity of fuel being injected into diesel‐type engines. There exist non‐linearities in the system, and usually, non‐linearities are neglected in modelling and control design, which makes the performance of the closed‐loop system degrade. Therefore, the authors take the non‐linearities of the rotary electromagnet and offsetting spring into consideration and establish the more detailed mathematical model in this study. Besides, the FQA system always confronts disturbances caused by external torque and input voltage variation in the real working condition. Furthermore, to deal with the non‐linearities and reject the disturbances, a generalised proportional integral observer (GPIO)‐based backstepping control approach is presented. By using a GPIO, the state estimations and disturbances estimation can be obtained at the same time. In addition, a theoretical analysis of the closed‐loop system is given, showing its asymptotic stability, even under acting lumped disturbance. The introduced control scheme exhibits satisfactory performance in terms of transient behaviour and disturbance rejection. Finally, a set of simulation and experimental tests are carried out to validate the feasibility as well as efficiency of the proposed control framework.
Structure of lamprophyres: a discriminant marker for Variscan and Alpine tectonics in the Argentera-Mercantour Massif, Maritime Alps
Authors: Filippi Marco , Zanoni Davide , Gosso Guido , Lardeaux Jean-Marc , Verati Chrystèle , Spalla Maria Iole
Published: November 2019

Structural and microstructural analyses are carried out in two sites of the Argentera-Mercantour Massif, Valscura and Val du Haut Boréon, where swarms of lamprophyres intruded into Variscan migmatites and early Permian granitoids. Efforts aim at defining the structural relationships between lamprophyres and country rocks, and at constraining the structural and metamorphic evolution the dykes record. Mesoscale structural data are synthesised in geologic maps originally surveyed at 1/10 000 scale, supported by form-surface maps at 1/100 scale. The lamprophyres are magnesian, calc-alkalic to alkali-calcic, and metaluminous; they emplaced at very shallow crustal levels intersecting three generations of ductile structures in the host migmatites (D1, D2, D3). Epidote- and actinolite-bearing mineral assemblages result from late-intrusive hydrothermal circulation that has not affected the host rocks. Mylonitic shear zones of Alpine age (D4) are continuous through migmatites, granites, and lamprophyres: in these latter, they are supported by albite, actinolite, biotite, chlorite, epidote, phengite, and titanite. This detailed multi-scale structural analysis, coupled with major and trace elements geochemistry, highlights two main results: i) the lamprophyres, which post-date both the late- to post-collisional “high-Mg” and the “low-Mg” granitoids, reflect the last magmatic event in the Argentera-Mercantour Massif related to the Permian-Triassic lithospheric thinning; ii) the metamorphic assemblages that support the Alpine shear zones in the lamprophyres are consistent with the transition between the greenschist and amphibolite facies conditions.
Effect of vibration on the formation of second phase particles in cast-rolling strips
Authors: Zhu Zhiwang , Xing Menglong , Sun Minghan , Wei Jieping , Du Fengshan
Published: November 2019

Taking 20CrMn steel as the experimental object, the vibration and non-vibration cast-rolling comparison experiments were carried out on the self-developed twin-roll strip vibration cast-rolling mill. And a series of tests such as tensile test, fracture morphology observation and energy spectrum analysis were carried out on the obtained cast-rolling strips. This paper focuses on the analysis of the test results from the perspective of the second phase particles, in order to explore the effect of vibration on the precipitation of the second phase particles in cast-rolling. The analysis results show that the vibration can promote the uniform distribution of alloying elements, thereby inhibiting the formation of large size second phase particles which are mainly concentrated in the central region of the strip in the late solidification stage, and promoting the precipitation of the dispersed small-sized particles in the high-temperature plastic deformation stage, and finally improving the mechanical properties of the cast-rolling strip. At the end of the paper, the influence of vibration parameters such as vibration amplitude and vibration frequency on the formation of second phase particles is further analyzed.
Effect of hybrid reinforcement at stirred zone of dissimilar aluminium alloys during friction stir welding
Authors: Ashok kumar R. , Raghav G.R. , Nagarajan K.J. , Rengarajan Sathish , Suganthi P. , Vignesh V.
Published: November 2019

The main objective of this work is to modify the mechanical as well as surface properties of weld nugget by the reinforcement of hybrid ceramic particles (alumina and silicon carbide). This is accomplished by combining friction stir welding (FSW) and friction stir processing (FSP) on dissimilar AA6101-T6 and AA1350 aluminium alloys. For this purpose, various levels of mixing proportions of Al2O3 & SiC particles are used with constant groove depth and width i.e. constant groove dimension. To evaluate the quality of joints, tensile, bending, micro-hardness, wear and microstructural studies are carried out. Among these, reinforcement of 100% alumina particles exhibits better mechanical and wear properties. On the other hand, reinforcement of 100% silicon carbide particles produces poor mechanical and wear properties. And also increment in percentage of reinforcement of alumina particles improves the mechanical and wear properties of weld nugget, when compared to increment in percentage of reinforcement of silicon carbide particles.
Effect of SiO2 containing slag for electroslag remelting on inclusion modification of 42CrMo steel
Authors: Liu Yu , Zhang Zhao , Li Guangqiang , Wu Yang , Wang Xijie , Li Baokuan
Published: November 2019

Five heats were carried out to study the effects of SiO2 containing slag for electroslag remelting (ESR) on inclusion characteristics of 42CrMo steel. Fluoride vaporization at elevated temperature from slags was also explored by thermogravimetric analysis. The results show that fluoride vaporization is dominated by slag viscosity and component activities in the melt. Slag composition has an important effect on the composition of the oxide inclusion. For 70 wt% CaF2–30 wt% Al2O3 slag, the compositions of oxide inclusions in remelted steel show no obvious differences compared with the virgin steel. Whereas, SiO2 content in oxide inclusions of steel processed by slag bearing SiO2 show an increasing trend with increase of SiO2 content in 50 wt% CaF2–CaO–SiO2 slag, and the MgO · Al2O3 inclusions are modified to (Al,Ca,Mg,Si)O inclusions with low melting temperature. Al2O3 contents in oxide inclusions are also closely related to the Al2O3 concentration in the molten slag, which increase with the addition of Al2O3 in slag bearing SiO2. In testing various slags, the incorporation of slag T2 with 50 wt% CaF2–30 wt% CaO–20 wt% SiO2 shows the highest cleanliness in remelted steel. This implies that slag T2 can be a promising slag for ESR process of alloy steel requiring Al content refinement due to less fluoride vaporization from slag and better inclusions modification.
Assessing of use of the Internet for personal reasons at lessons at school: A Validation of the Cyberloafing Scale
Authors: Sivrikova Nadezhda , Roslyakova Svetlana , Sokolova Nadezhda , Moiseeva Elena
Published: November 2019

Emergence of a possibility of Internet access at school bears new opportunities and risks too. The tendency to growth of number of the pupils Internet use for non-class-related purposes in the classroom (Cyberloafing) causes concern. Studying of this new phenomenon at the Russian school is complicated due to the lack of reliable and valid techniques. Therefore, adaptation of a scale of a cyberloafing of Y. Akbulut, etc. became an objective of this research. We translated into Russian of 29 items of a technique which were estimated by school students by means of 5-point Laykert scales. Results of application of a scale showed that its items form 5 factors. These are online shopping, accessing online content, activity on social networks, sharing information, socialization. The items of a factor of playing online games did not receive confirmation of validity and internal consistency. They need to be reconsidered. The received factors have sufficient reliability (the Cronbach’s alpha (α) values of all the factors range from 0.77 to 0.881). Work makes a contribution to studying of a cyberloafing at school.
Features of professional identity of students “helping” occupations with different levels of self-efficacy
Authors: Tushnova Yuliya , Rashchupkina Yuliya , Khachaturyan Nelli
Published: November 2019

Professional identity is an indicator of the level of mastery of professional activity. One of the indicators for assessing the formation of professional identity is the attitude to yourself as a future and current professional. Here we can talk about both the real and the predicted of the professional self-rating. This study focuses on predicted self-esteem. Self-efficacy is a professionally important meta-quality, positively correlated with the results of professional activity. The problem of self-efficacy in the process of formation of professional identity of “helping” occupations specialists is important from the point of view of assessing professional maturity and psychological and pedagogical support of the formation of professional personality. The study sample consisted of 93 students of 1 course of study of psychological and medical specialties aged 17 to 21 years (M=17.9, SD=3.2 (41.5% men)). The methods of research were the method of determining the level of self-efficacy (J.E. Maddux, M. Sherer, modification of L. Boyarintseva under the direction of R. Krichevsky) and “Personal differential”. The study describes the features of the predicted self-esteem at different stages of professionalization of students “helping” occupations with different levels of self-efficacy.