bluuebunny/crossref_metadata_2025 huggingface dataset:
Compact Dual-Band Rectifier with Self-Matched Branches Using Comprehensive Impedance Control
Authors: Barakat Adel , Jordan Willy , Pokharel Ramesh K.
Published: February 2025

The use of multi-band matching for rectifiers leads to design complexity. Instead, recent advancements suggested self-matched branches combined in parallel to enable multiband operation. However, this method controls only the imaginary part. In this letter, we propose an efficient dual-band rectifier with compact realization. The rectifier consists of two self-matched parallel branches. Each branch provides comprehensive impedance control over real and imaginary parts in the corresponding band independent of the design frequency. The branch impedance matching is analyzed theoretically, and design equations are presented. To verify the proposed theory, a compact dual-band rectifier was fabricated with a compact area of only 0.42 cm2 after excluding the area required for the RF connector. The measured RF-DC power conversion efficiency (PCE) was > 50% for input power (Pin) ranging from -5.5 dBm to 11 dBm at 390 MHz with a peak of 69%. Also, the PCE was > 50% for Pin ranging from -4 dBm to 12 dBm at 690 MHz with a peak of 68%. The fabricated rectifier operates with a wide load range from 0.5 KΩ to 3 KΩ with PCE > 50% at both bands when Pin=5 dBm.
Air Pollution Monitoring using Cost-Effective Devices
Authors: Colléaux Yanis , Willaume Cédric , Mohandes Bijan , Nebel Jean-Christophe , Rahman Farzana
Published: February 2025

Given the significant impact of air pollution on global health, continuous and precise monitoring of air quality in all populated environments is crucial. Unfortunately, even in the most developed economies, current air quality monitoring networks are largely inadequate. The high cost of monitoring stations has been identified as a key barrier to widespread coverage, making cost-effective air quality monitoring devices a potential game changer. However, the accuracy of measurements obtained from low-cost sensors is affected by many factors, including gas cross-sensitivity, environmental conditions, and production inconsistencies. Fortunately, machine learning models can capture complex interdependent relationships in sensor responses, and thus can enhance their readings and sensor accuracy. After gathering measurements from cost-effective air pollution monitoring devices placed alongside a reference station, the data were used to train such models. Assessment of their performance showed that models tailored to individual sensor units greatly improved measurement accuracy, boosting their correlation with reference-grade instruments by up to 10\%. Nonetheless, the research also revealed that inconsistencies in the performance of similar sensor units can prevent the creation of a unified correction model for a given sensor type.
Effects of Methylprednisolone and Hyaluronic Acid on the Endometrium in Experimentally Induced Asherman Syndrome Rat Models: A Prospective Laboratory Study
Authors: Genco Mehmet , Genco Merve , Vural Fisun , Koç Nermin
Published: February 2025

Background and Objectives: This study aimed to evaluate the histopathological effects and tissue VEGF levels of combined methylprednisolone and hyaluronic acid treatment in a rat model with experimentally induced Asherman Syndrome prospective laboratory study. Materials and Methods: Twenty-six female Sprague Dawley rats were used. Trichloroacetic acid was applied to the right uterine horns of all groups to induce adhesion formation. First, we induced an Asherman model in 2 rats (Group 1). The remaining rats were divided into 3 groups. Group 2 received intrauterine hyaluronic acid treatment, Group 3 received oral methylprednisolone treatment, and Group 4 received both treatments. Histopathologically inflammation, gland count, and fibrosis levels were assessed. VEGF levels were analyzed immunohistochemically. Results: Hyaluronic acid treatment increased uterine lumen diameter and vascularization. Methylprednisolone treatment increased gland count and uterine wall thickness while decreasing inflammation and fibrosis scores. Combined treatment further enhanced these effects (p<0.05). Conclusions: Methylprednisolone treatment significantly prevented adhesion formation and reduced inflammation and fibrosis scores compared to hyaluronic acid treatment alone. The combined treatment adds to the effects of hyaluronic acid treatment alone and provides better healing.
Origin and Development of Zooplankton and Macrozoobenthos Communities in the Primary Succession of a Temporarily Anthropogenically Regulated Artificial Lake
Authors: Ivanov Pencho
Published: February 2025

This study aims to observe the emergence and development of zooplankton and macrozoobenthos communities in an artificial water basin under an anthropogenically controlled hydrological regime. The lake, located in the center of Sofia, Bulgaria, is a free-flowing water body with a concrete bottom and walls. It undergoes annual cleaning before refilling each spring, effectively resetting biological colonization. Zooplankton and macrozoobenthos samples were taxonomically identified and statistically analyzed. The absence of predatory pressure and the stable environmental conditions provided by the flowing nature of the lake facilitates the formation of a viable zooplankton community, which plays a crucial role in ecosystem productivity. However, macrozoobenthos does not establish a stable community and is primarily represented by chironomids. Different filling conditions each year influence the structure of the zooplankton community.
Observational Study on the Heat Detection, Pregnancy, and Conception Rates of Cooled High-Yielding Holstein Cows
Authors: Borş Silviu-Ionuț , Vintilă Vasile , Borș Alina , Floriștean Viorel-Cezar
Published: February 2025

In dairy cows, future advancements will require new strategies to minimize additional interventions and maintain reproduction at thermo-neutral level in high yielding dairy cows. Thus, this observational study used data from a high-yielding dairy farm in northeastern Romania over two consecutive years. In both years an automated cooling system was used, in order to maintain the temperature humidity index within the range of 65-75 when environmental conditions rise above this value. The study found that heat detection rates were high in both years and the values are similar (P > 0.05). However, the probability of conception/pregnancy was negatively affected by the cow's parity, season, and repeat breeding. As a result, pregnancy and conception rates showed a consistent trend over the two years and the values are similar. According to the observational data from the current study, we observed that current cooling systems are insufficient for maintaining reproduction at a thermo-neutral level for high-yielding dairy cows. Thus, conception and pregnancy rates were significantly affected during the summer (P < 0.05). Notably, the effects on conception rates extended into autumn (P < 0.05) across both years. As expected, multiparous and repeat-breeding dairy cows had the lowest reproductive performance (P < 0.05).
3D Spatial Perception of Blueberry Fruits Based on Improved YOLOv11 Network
Authors: Zhao Kun , Li Yuhuan , Liu Zunmin
Published: February 2025

Automated harvesting of blueberries using a picking robot places a greater demand on the 3D spatial perception performance of blueberry fruits, as the robot’s grasping mechanism needs to pick blueberry fruits accurately at specific positions and in particular poses. To achieve this goal, this paper presents a method for blueberry detection, 3D spatial localization, and pose estimation using visual perception, which can be deployed on an OAK depth camera. Firstly, a blueberry and calyx scar detection dataset is constructed to train the detection network and evaluate its performance. Secondly, the blueberry and calyx scar detection model based on a lightweight yolov11 (the eleventh version of the You Only Look Once) network with an improved depth-wise separable convolution (DSC) module is designed, and a 3D coordinate system relative to the camera is established to calculate the 3D pose of the blueberry fruits. Finally, the above detection model is deployed onto the OAK depth camera, leveraging its depth estimation module and three-axis gyroscope to obtain the 3D coordinates of the blueberry fruits. Experimental results demonstrate that the method proposed in this paper can accurately perceive blueberry fruits at various maturity levels, achieving a detection accuracy of 95.8% mAP50-95, a positioning error of less than 1 centimeter within 0.5 meters, and an average 3D pose error of 19.2 degrees while maintaining the detection frame rate of 13.4 FPS (Frames Per Second) on the OAK depth camera, which can provide effective picking guidance for the mechanical arm of picking robot.
Utilising Style 3D Fashion Design Software to Automatically Generate Hanfu Pattern
Authors: Ren Juan , Daoruang Krisada , Apiwathnasorn Chalisa
Published: February 2025

Traditional pattern-making depends on the master, time-consuming, waste, limited-flexibility. This study aims to develop innovative solutions，Take Chinese traditional clothing “Hanfu”as an example. By analyzing the data between human body, clothing and sewing patterns, we can find the change rules of the key points and the key lines, forming the design line and the loose rules between sewing pattern and human body. Explore computer-aided design software and artificial intelligence to automatically generate garment sewing patterns that can be used for virtual simulation and production. The results show that input a single two-dimensional image or design manuscript in the Style3D software can quickly get the sewing patterns what designer needed in a few seconds. The experimental results were compared with the quality and speed of traditional pattern-making to optimize the accuracy of auto-generation. This study shows that the automated generation of pattern-making can be greatly improve the work efficiency of clothing production，helped the fashion industry maintain strong competitiveness in the fast-paced and demanding market.
Evaluating Pretreatment Strategies with Modeling for Reducing Scaling Potential of Reverse Osmosis Concentrate: Insights from Ion Exchange and Activated Alumina
Authors: Mejía-Saucedo Carolina , Stoll Zachary , Senanayake Punhasa , Xu Pei , Wang Huiyao
Published: February 2025

Reverse osmosis concentrate (ROC) treatment is critical for enhancing water recovery, especially in regions facing water scarcity. The high concentrations of total dissolved solids (TDS), hardness (Ca2+ and Mg2+) and silica, present significant challenges for ROC treatment due to their high scaling potential. Developing effective pretreatment strategies, such as ion exchange (IX) and activated alumina (AA), to mitigate scaling is essential for improving water recovery. This study investigates the effectiveness of dif-ferent ion exchange (IX) resins and activated alumina (AA) in removing hardness and silica from brackish water ROC, through batch isotherm studies, continuous column experiments, regeneration, impact of operating conditions, model simulation, and pre-liminary costs analysis. The ROC is characterized by TDS 12,445 mg/L, Ca²⁺ 847 mg/L, Mg²⁺ 212 mg/L, and silica 160 mg/L. Hardness removal was evaluated using two types of strong acid cation (SAC) IX resins and silica removal using three types of strong base anion (SBA) IX resins and three types of AA. While IX was effective in removing hardness and silica during the initial stages of column experiments, hardness breakthrough occurred at 17–33 bed volumes (BV) for SAC and 5 BV for silica using SBA, due to their high con-centrations in ROC. In contrast, AA demonstrated superior and sustained silica removal, reducing silica concentration in ROC by up to 65% and maintaining performance for up to 800 BV without reaching saturation. Model simulation of a secondary RO treating ROC after the IX and AA pretreatment indicated an additional water recovery of ~70% using antiscalants. While this study demonstrates the potential for achieving higher water recovery, significant challenges remain, including limited capacity of IX resins for ROC treatment, which necessitates frequent regeneration and adds operational costs, as well as the restricted regeneration capacity of AA. These findings emphasize the critical need for developing advanced materials and optimized strategies to enhance the efficiency of ROC treatment processes.
Development of a Maritime Transport Emulator to Mitigate Data Loss from Shipborne IoT Sensors
Authors: Park ChaeRim , Park DoMyung , Kim TaeHoon , Kang Byung O , Park ByungKwon
Published: February 2025

Recently, the maritime logistics industry has been transitioning to smart logistics by leveraging such technologies as AI and IoT. In particular, maritime big data plays a significant role in providing various services, including ship operation monitoring and greenhouse gas emissions assessment, and is considered essential for delivering maritime logistics services. Marine big data comprises real-world data collected during ship operations, but it is susceptible to loss due to temporal and environmental constraints. Together with identifying and addressing the root causes of data loss, it is mandatory to supplement the loss by analyzing and utilizing the collected data. This study proposes an emulator that repetitively generates new data such as location data, data count, and average distance using maritime transport data cumulated up to now. The location data is generated using the cumulative distance and trigonometric ratios based on the location information of standard routes. The data count and average distance are calculated based on user-input parameters such as voyage time and data interval. The generated data is inserted into a database and monitored on a map in real time. To evaluate the emulator's performance, experiments were conducted using the maritime transport route data, and the results demonstrated its effectiveness.
GravitationalWaves from Alena Tensor
Authors: Ogonowski Piotr
Published: February 2025

Alena Tensor is a recently discovered class of energy-momentum tensors that provides a general equivalence of the curved path and the geodesic for the analyzed spacetimes which allows for a faithful reproduction of GR results in flat spacetime. In this paper it is shown that using this approach naturally leads to the existence of gravitational waves, which can be interpreted as vacuum pressure waves with tensor amplitude. The calculated trace of the metric tensor describing curved spacetime turned out to be invariant. A certain simplification of the analysis of gravitational waves has also been proposed, which may help both in their analysis and in the proof of the validity of the Alena Tensor. The article has been supplemented with the Alena Tensor equations with a positive value of the electromagnetic field tensor invariant (related to cosmological constant) which may help in further analysis of this approach.
Effects of Butyric Acid Supplementation on the Gut Microbiome and Growth Performance of Weanling Pigs Fed a Low-Crude Protein, Propionic Acid-Preserved Grain Diet
Authors: Connolly Kathryn Ruth , Sweeney Torres , Ryan Marion T. , Vigors Stafford , O’Doherty John V.
Published: February 2025

Reducing crude protein (CP) in weaner pig diets lowers post-weaning diarrhoea risk but may impair growth performance. This study aimed to identify benefical effects of organic acid (OA)-preserved grain and butyric acid (BA) supplementation on gut health and growth in low-CP diets. At harvest, grain was divided into 2 batches: one dried at 65 °C, the other treated with a propionic acid. Ninety-six piglets (28 days old) were assigned to four treatments: (1) dried grain, (2) OA-preserved grain, (3) dried grain+3% BA, and (4) OA-preserved grain+3% BA. On day 8, microbial composition, inflammatory markers, volatile fatty acids, and intestinal morphology were assessed. The OA-preserved diet improved feed conversion ratio (P < 0.05), increased beneficial gut bacteria (P < 0.01), elevated caecal butyrate (P < 0.05), reduced jejunal CXCL8 expression (P < 0.05), and enhanced nutrient digestibility (P < 0.01). BA reduced feed intake (P < 0.05), improved nutrient digestibility (P < 0.01), decreased colonic Proteobacteria (P < 0.05), and increased colonic propionate and butyrate (P < 0.01). Combining OA-preserved grain with BA elevated ileal Proteobacteria and Pasteurellaceae (P < 0.05). In conclusion, while OA-preserved grain improves feed efficiency, nutrient digestibility, and gut microbiota, and suplementing butyric acid enhances nutrient digestibility but reduces feed intake, their combination may disrupt microbial balance.
IL6 in Combination with Either NfL, NTproBNP, or GFAP Can Safely Rule Out Intracranial Injuries in Children with Mild Traumatic Brain Injury
Authors: Chiollaz Anne-Cécile , Pouillard Virginie , Seiler Michelle , Habre Céline , Romano Fabrizio , Ritter Schenk Céline , Spigariol Fabian , Korff Christian , Maréchal Fabienne , Wyss Verena , Gruaz Lyssia , Montaner Joan , Manzano Sergio , Sanchez Jean-Charles
Published: February 2025

Background: Mild traumatic brain injury (mTBI) in children is a public health concern resulting in one of the main causes of pediatric emergency department (PED) visits. However, the acute care of mTBI patients remains challenging due to the limited use of specific and safe diagnostic tools. Objectives: To evaluate the performances of combined blood biomarkers to safely rule out intracranial injuries in children with mTBI in the PED. Methods: This was a prospective multicenter cohort study of children aged 0-16 years who presented to the PED within 24 hours of sustaining mTBI. Blood was drawn at admission and levels of IL6, NfL, NTproBNP, GFAP, IL10, S100b, and HFABP were analyzed. Patients were dichotomized in two groups: 1) with intracranial injuries (ICI) on computed tomography scan (CT) (= CT+) and 2) without ICI on CT or kept in observation without CT (= CT- & Obs.). Biomarker age correlation was assessed in a healthy group of children aged 0-16 years. Results: 419 children with mTBI and 99 healthy children were enrolled. All the single and duplex combinations of blood-biomarkers were tested for their capacity to safely rule out intracranial injuries. IL6 was present in the three best combinations reaching 100% sensitivity (SE) and with the highest associated specificity (SP). IL6 + NfL yielded 61% SP, followed by IL6 + NTproBNP with 60% SP, and IL6 + GFAP with 57% SP. Neither IL6 nor NTproBNP were found to be age correlated. Conclusions: IL6 in combination with either NfL, NTproBNP, or GFAP could safely rule out 61% of children without ICI (corresponding to 33/79 unnecessary CT scans and 212/322 observation stays at PED). Blood panels incorporating IL6 show promise as decision-making tools for the acute management of children with mTBI. However, further external studies are required to validate these findings.
Comparative Analysis of Endophytic Curtobacterium Species Reveals Commonalities and Adaptations
Authors: Arhin Annabel , Foriska Isabella , Wiegand Sydney , Brown Kiersten , Crayne Kylee , Stroscio Kaitlyn , Mohan Rajinikanth
Published: February 2025

Curtobacterium species are increasingly recognized as plant pathogens and soil decomposers, but their prevalence and function as plant endophytes is less clear. In this study, we isolated six endophytic Curtobacterium species from fruits, flower petal (previously unreported) and stem tissue of plants from diverse environments and examined their general characteristics. We found that all Curtobacterium endophytes- belonging to three major Curtobacterium clusters- C. oceanosedimentum (a group not previously recognized as endophytic), C. luteum, and C. flaccumfaciens- shared some common features. All or nearly all isolates tested were pigmented, displayed moderate salt tolerance and, surprisingly, were psychrotolerant, being able to grow at 6°C. The exception was a fruit C. luteum isolate that appears to have evolved thermotolerance (up to 45°C) instead as a likely adaptation to its environment. All isolates were able to metabolize starch and casein and solubilize inorganic phosphate, indicating conserved secreted hydrolase activity, but only isolates in the C. oceanosedimentum group were able to absorb and metabolize citrate. Finally, all endophytes tested were able to ferment the plant sugars sucrose and fructose, while they differed in their ability to use other sugars. Thus, this study documents common traits and adaptations in various Curtobacterium endophytes and the presence of these isolates in floral and fruit organs implies possible seed-borne inheritance of these isolates.
ClipKIT in the Browser: Fast Online Trimming of Multiple Sequence Alignments for Phylogenetics
Authors: Steenwyk Jacob L. , Buida Thomas
Published: February 2025

Multiple sequence alignment trimming can help improve phylogenetic signal and reduce computational load. ClipKIT trims multiple sequence alignments by retaining phylogenetically informative sites and removing all others. Here, we present a web browser application for ClipKIT, which supports DNA, protein, and codon data types in FASTA format. The web browser application can process one or many multiple sequence alignment files, which users can subsequently download. Users can also view the trimmed multiple sequence alignment using a web-based multiple sequence alignment viewer. ClipKIT is available at https://clipkit.genomelybio.com, is free and open to all users, and there is no login requirement. ClipKIT in the browser aims to broaden the accessibility of web-based tools for phylogenetics research.
Linguistic Profiling and the Future of Spanish in the United States: A Sociolinguistic Analysis
Authors: Guarín Daniel
Published: February 2025

In this essay, I would like to explore the intersection of linguistic profiling, sociopolitical dynamics, and the future of Spanish in the United States, to emphasize the impact of contemporary immigration policies on language use among Hispanic communities. Specifically, I aim to examine how anti-immigrant rhetoric, intensified under the 2025 Trump administration’s policies, reinforces linguistic discrimination and creates a climate of fear for Spanish speakers and the use of their language in pubic. By analyzing the historical presence of Spanish in the U.S. and the challenges posed by linguistic profiling, I would like to highlight the erosion of linguistic rights and the broader consequences for social inequality. I will also consider the roles of schools and churches as spaces for language preservation and cultural expression, which are increasingly threatened by immigration enforcement measures. In advocating for sociolinguistic justice, this essay calls for policies that recognize and protect the linguistic rights of Spanish speakers, promoting multilingualism as a strength rather than a threat.
An RB1CC1 Missense Variant in Nova Scotia Duck Tolling Retrievers with Degenerative Encephalopathy
Authors: Guo Juyuan , Bullock Garrett , O'Brien Dennis P. , Johnson Gary S. , Katz Martin L
Published: February 2025

A slowly progressive neurological disorder classified as degenerative encephalopathy (DE) occurs in Nova Scotia Duck Tolling Retrievers. The disease is characterized by frequent episodes of pronounced involuntary movements during sleep, cognitive impairment, anxiety, heightened sensitivity to sensory stimuli, and compulsive behaviors. The onset of these signs occurs between 2 months and 5 years of age. Late signs include aggressive behavior, gait abnormalities, and urinary and fecal incontinence. The clinical signs are accompanied by degeneration of the cerebellum, caudate nucleus, and substantia nigra. Next-generation sequencing was used to generate whole-genome sequences from the DNA of affected and unaffected Nova Scotia Duck Tolling Retrievers. The resulting sequences were aligned to the Dog10K_Boxer_Tasha reference genome assembly and the whole genome sequences (WGS) of 334 additonal control canine whole genome sequences generated by the University of Missouri Canine Genetics Laboratory. Analysis of the WGS data identified a missense variant in RB1CC1 exon 22 chromosome 29:4891014, C>T that was uniquely homozygous in the affected dog. This variant predicts a p.G1503R change in the amino acid sequence of RB1CC1. Genotyping of 2,950 Nova Scotia Duck Tolling Retrievers at the variant locus found complete concordance between the disease phenotype and RB1CC1 genotype. RBCC1 is an essential component of a protein complex that mediates the initiation of autophagosome formation. Therefore, it appears likely that the disease results at least in part from impaired autophagy. Consistent with possibility, caudate nucleus neurons of an affected dog were found to contain abnormal lysosomal storage body-like inclusions bodies with heterogenous contents. This disorder could serve as a valuable model to elucidate the mechanisms underlying human diseases associated with impaired autophagy. Identification of the disease-causing DNA sequence variant will enable owners of Nova Scotia Duck Tolling Retrievers to screen their dogs for the RB1CC1 risk variant.
Infrared Absorption of Laser Patterned Sapphire Al2O3 for Radiative Cooling
Authors: Zheng Nan , Smith Daniel , Ng Soon Hock , Huang Hsin-Hui , Stonytė Dominyka , Appadoo Dominique , Vongsvivut Jitraporn , Katkus Tomas , Le Nguyen Hoai An , Mu Haoran , Nishijima Yoshiaki , Grineviciute Lina , Juodkazis Saulius
Published: February 2025

The reflectance (R) of linear and circular micro-gratings on c-plane sapphire Al2O3 ablated by a femtosecond (fs) laser, were spectrally characterised for thermal emission ∝ (1 − R) in the mid-to-far infrared (IR) spectral range. An IR camera was used to determine the blackbody radiation temperature from laser patterned regions, which showed (3 − 6)% larger emissivity dependent on the grating pattern. The azimuthal emission curve closely followed the Lambertian angular profile ∝ cos θa at the 7.5-13 µm emission band. The backside ablation method on transparent substrates was employed to prevent debris formation during energy deposition as it applies a forward pressure of > 0.3 GPa to the debris and molten skin layer. The backside ablation maximises energy deposition at the exit interface where the transition occurs from the high-to-low refractive index. Phononic absorption in the Reststrahlen region 20–30 µm can be tailored with the fs-laser inscription of sensor structures/gratings.
Research Agendas on Ageing and Longevity: Linking Research and Policy
Authors: Sidorenko Alexandre , Leichsenring Kai
Published: February 2025

This review article is devoted to the role of research agendas in linking research and policy in the field of ageing and longevity. After emphasising the importance of research evidence in international policy frameworks on ageing and defining the main parameters of research agendas, the authors turn to describing how research agendas can play a key role in bridging research and policy on population ageing and individual longevity. Examples of international (global), regional and national research agendas are presented. Finally, the authors reflect on the benefits and current limitations of research agendas in supporting evidence-based policy and highlight the potential role of research agendas in developing appropriate and timely responses to the challenges and opportunities of population ageing and individual longevity.
Evaluating Bioassay Efficacy Larvae of Extremophile Bacillus Species for Environmentally Safe Control of Aedes aegypti
Authors: Baeshen Mohammed Nabih , Kusa Abdulaziz M , AL-Ghamdi Ahmad K , Algashgari Basim , Alnahari Alaa A , Alqurashi Shatha I , Mahyoub Jazem A
Published: February 2025

Mosquito-borne diseases pose significant public health challenges, necessitating inno-vative and sustainable control measures. This study evaluates the larvicidal potential of six extremophile Bacillus species against Aedes aegypti larvae, focusing on dose-response relationships, resistance trends, and genetic diversity. Regression analy-sis revealed a significant positive correlation between concentration and larval mortal-ity across species, with B. sonorensis and B. paramycoides demonstrating superior po-tency at lower concentrations (LC₅₀: 19.72 ppm and 23.41 ppm, respectively). Probit analysis confirmed that B. sonorensis is the most effective larvicide, achieving high mortality rates with minimal concentrations. In contrast, B. licheniformis and B. ster-coris exhibited limited efficacy, requiring significantly higher doses to achieve compa-rable results. Resistance analysis highlighted an inverse relationship between toxicity index and resistance ratio, with B. sonorensis maintaining high efficacy even in re-sistant mosquito populations (Resistance Ratio: 1). Furthermore, phylogenetic analysis based on 16S rRNA gene sequences revealed distinct evolutionary relationships among species, with B. rugosus and B. tequilensis clustering closely, suggesting functional similarities. The genetic divergence of B. licheniformis aligns with its lower larvicidal performance. Overall, this study underscores the potential of B. sonorensis and B. paramycoides as robust candidates for mosquito control programs, particularly in re-sistance-prone environments. The findings provide valuable insights into optimizing microbial larvicides by tailoring species-specific application strategies and leveraging genetic diversity within the Bacillus genus.
Applications of Diquafosol Sodium in Ophthalmology: A Comprehensive Review on Therapeutic Utility
Authors: Tan Chelsea Qiu Lin , Wu Duoduo , Toh Xin Yun , Lim Blanche Xiaohong , Shih Kendrick Co , Tong Louis , Lim Chris Hong Long
Published: February 2025

Diquafosol is a purinergic P2Y2 receptor agonist that is garnering much interest for its potential therapeutic benefits in dry eye disease (DED) management and is used commonly in Asia. Diquafosol’s mechanism of action involves enhancing fluid secretion from conjunctival epithelial cells and promoting mucin secretion, thereby improving tear film stability and ocular surface lubrication. Clinical trials have demonstrated its efficacy in effectively targeting all three DED subtypes, aqueous-deficient, decreased-wettability, and evaporative dry eye, by increasing tear production leading to improvements in objective markers and reducing subjective symptoms of DED. Adverse effects are generally mild and transient, including ocular irritation and discomfort. This review explores future research directions including its efficacy in certain subtypes of DED yet to be thoroughly explored, inter-product superiority, creation of various formulations, recommended treatment duration and its potential combination therapies. Overall, this review seeks to provide an overview of the pharmacological properties, clinical efficacy, safety profile, clinical utility, long-term usage, and prospects of diquafosol in managing DED. Diquafosol represents a promising novel option in the armamentarium against DED to address the underlying pathophysiology of this common ocular condition.
The Composition of Essential Oils from Different Parts of Gilia capitata Sims
Authors: Raal Ain , Liira Jaan , Lepiku Martin , Ilina Tetiana , Kovalyova Alla , Strukov Pavel , Koshovyi Oleh
Published: February 2025

Bluehead gilia or bluefield gilia (Gilia capitata Sims) from the family Polemoniaceae is an annual herbaceous plant widely distributed in the western regions of North America, but cultivated as an ornamental flower in various regions to support pollinators. The chemical composition of the plant has not been studied before. For the first time, essential oil (EO) was obtained by hydrodistillation from the different parts of gilia, harvested in Estonia. The yield of EOs was from 0.42 to 1.97 mL/kg, with the greatest yields from seeds, flowers, fruits, and leaves. Its component composition was studied using the GC-MS method. 118 compounds have been identified. The EO of flowers was dominated by the hexahydrofarnesyl acetone (19.1%), followed by palmitic acid (12.2%), γ-decalactone (7.1%), (Z)-2-p-menthen-1-ol (3.6%). Hexahydrofarnesyl acetone was also dominant in most parts of the G. capitata. The predominant compounds in the EO of leaves were diterpene alcohols: phytol (23.3%), isomanool (12.1%) and sclareol (4.5%), apocarotenoids, C13-norisoprenoid (E)-β-ionone (4.5%). The most dominant compounds in EO of stems are isomanool (8.3 %), sclareol (6.7%) and (E,E)-2,4-decadienal (5.3%). The dominant in the fruits were hexahydrofarnesyl acetone (18.2%), palmitic acid (8.0%), heptacosane (5.3%) and γ-decalactone (4.6 %). The dominant in the shell were (+)-epi-bicyclosesquiphellandrene (15.4%), β-elemene (8.5%) and pentadecanal (6.3%). The dominant in the seeds were hexahydrofarnesyl acetone (15.2%), palmitic acid (11.1%), 1,3-d’dimethylbenzene (10.3%) and heptacosane (5.0%). The dominant in the root were (-)-myrtenol (25.7%), (E)-myrtanol (16.4%), palmitic acid (8.1%) and 2-pentylfuran (2.9%). The results hint at further study options on the antimicrobial and anti-inflammatory effects of G. capitata.
Risk Factors and Clinical Outcomes in Nonagenarians with Acute Coronary Syndrome: A Case-Control Study
Authors: Demirbaş Zeynep Ece , Zeren Gönül , Can Fatma , Karabay Can Yücel
Published: February 2025

Objective: With the growing number of individuals over the age of 90 (nonagenarians), understanding the risk factors and clinical outcomes associated with acute coronary syndrome (ACS) in this population has become increasingly important. This study aims to compare demographic, biochemical, and clinical parameters between nonagenarian ACS patients and a control group of healthy individuals within the same age bracket as well as to analyze differences within the ACS group according to myocardial infarction type and evaluate the impact of percutaneous coronary intervention (PCI) on in-hospital mortality. Methods: This retrospective case-control study included 104 patients aged 90-100 years diagnosed with ACS for the first time between January 2022 and January 2024. The patients were categorized into ST-elevation myocardial infarction (STEMI) and non-ST-elevation myocardial infarction (NSTEMI) groups based on their electrocardiographic findings. The control group consisted of 113 healthy individuals in the same age range who had no history of coronary artery disease. Data on traditional risk factors, including lipid profiles and family history, were analyzed using logistic regression models. Additionally, differences in clinical outcomes, including length of hospital stay and mortality rates, were evaluated based on the application of PCI. Results: The ACS group exhibited significantly higher glucose, white blood cell count, and total cholesterol levels, along with lower hemoglobin and mean corpuscular volume, compared to the control group (p<0.05). While no significant difference was found in low-density lipoprotein (LDL) levels, high-density lipoprotein (HDL) levels were significantly lower in ACS patients (p<0.001). Family history played a more substantial role in the STEMI group compared to the NSTEMI group (p=0.049). Additionally, STEMI patients were more likely to undergo invasive procedures, which were associated with reduced in-hospital mortality (p=0.042). In contrast, no significant difference in mortality was observed in the NSTEMI group based on PCI status. Conclusion: This study highlights the distinct risk profiles of elderly ACS patients, emphasizing the critical role of low HDL levels and family history, particularly in STEMI cases. Furthermore, PCI was shown to reduce in-hospital mortality rates in STEMI patients, suggesting that invasive treatment approaches may be beneficial even in this vulnerable population. Personalized and multidisciplinary management strategies are essential for this vulnerable population. Further prospective research is needed to validate these findings and guide clinical decision-making for nonagenarians.
Evaluación de funcionalidad de ajuste y propiedades mecánicas de una prótesis transradial para impresión 3D
Authors: Orquiz Avila Paola Lizeth , Meraz Tena Erika Guadalupe , Oropeza Casillas José Ricardo
Published: February 2025

Este trabajo planteó evaluar la funcionalidad de ajuste de un diseño propuesto para una prótesis mecánica transradial mediante impresión 3D y comparar las propiedades mecánicas de tres materiales: PLA, ABS y PETG. Se obtuvieron medidas antropométricas de EBSCOhost y se ingresaron al diseño para evaluar su funcionalidad de ajuste. Además, se realizaron simulaciones para comparar las propiedades mecánicas de los materiales en diferentes posiciones y fuerzas, con el fin de identificar el material con el mejor desempeño. Posteriormente, se realizó un prototipo con dicho material seleccionado para realizar pruebas de rendimiento con un equipo Mark-10 para compararlas con las simulaciones. Los datos de la evaluación del ajuste mostraron variaciones menores que no supusieron un obstáculo para su funcionalidad mecánica, mientras que las evaluaciones de la tensión von Mises, desplazamientos, deformación, transferencia de calor, compresión, costos de adquisición y accesibilidad, establecieron al PLA como el más idóneo. Finalmente, el prototipo demostró que, tanto en simulación como en laboratorio, las piezas sufrieron un mayor desplazamiento en la posición de supinación. A pesar de los daños mínimos en la unión mano-antebrazo, este diseño ofrece una alternativa accesible, ajustable y económica, además de reducir significativamente el tiempo de fabricación a comparación de los dispositivos tradicionales.
Implementación de un método para el control de inventario en una microempresa familiar
Authors: Galaviz-Magallanes Luis Enrique , Rodríguez-Morachis Manuel Alonso , Gutiérrez-Hernández Mónica Gabriela
Published: February 2025

Las micro, pequeñas y medianas empresas (MIPYMES) conforman la base de la economía nacional e internacional. Sin embargo, constantemente se enfrentan a una gran diversidad de retos que en muchas ocasiones no pueden superar. Por esta razón, en este artículo se hace énfasis en la importancia de tener como mínimo un control de inventario que permita conocer en tiempo real la situación y establecer estrategias para incrementar la rentabilidad. El objetivo de este trabajo es la implementación de un método de control de inventario en una microempresa familiar de Ciudad Jiménez, Chihuahua, México. La metodología se compone de tres etapas: crear una base de datos, realizar un análisis descriptivo de las ventas e implementar un método de máximos y mínimos. Entre los resultados se reporta una dispersión elevada en el comportamiento de las ventas, así como un exceso de inventario en tres de los cinco productos seleccionados. En conclusión, en este estudio se evidencia la importancia de contar con un control de inventario que permita conocer el comportamiento de las ventas, así como evitar faltantes o excedentes que impactan directamente en la rentabilidad de la empresa.
Hubungan antara Kompensasi dengan Komitmen Organisasi Guru Sekolah Menengah Pertama Swasta di Kecamatan Pulo Gadung
Authors: Mukarrom Tri Sulistyo Jati , Karnati Neti , Listyasari Winda Dewi
Published: February 2025

This study aims to determine the relationship between compensation andorganizational commitment junior high school teachers in the district Pulo Gadung. Theresearch approach is a quantitative approach to the method used survey methods. Thisstudy uses correlational study analysis. The study population was Junior highschoolteachers in the district Pulo Gadung with the sample amounted to 79 teachers. Samplingwas done randomly by using simple random sampling with data collection using thequestionnaire. It can be concluded that there is a relationship between compensation andorganizational commitment. This means that the higher the compensation it will furtherenhance the organization's commitment junior high school teachers in the district PuloGadung.
Manajemen Pelatihan Mastering Islamic Finance di Pusdiklat Keuangan Umum
Authors: Amalina Fanny , Matin Matin , Muhammad Amril
Published: February 2025

This research was conducted at the General Finance Training Center. Whichaims to identify training management Mastering Islamic Finance process. This researchwas done since october 2016 to january 2017. This research was using a qualitativeapproach with descriptive methods. Data collection is done through interview,observation and documentation study. Source of research data comes from keyinformants head of planning and development division, head of implementation division,and several informants supporters such as head of curriculum subdivision, currculumsubdivision and implementation subdivision staff.The results of this study indicate that: (1) Planning of Mastering Islamic FinanceTraining begins with training need analysis, preparing curriculum, materials, teachingmaterials, assign teachers, the requirements of the participants, the venue for training.Implementation of Mastering Islamic Finance Training at the general finance trainingcenter appropriate with the guidelines. (2) Implementation of the training activitiescarried out through several stages including methods independent study and face-to-face.The determination of participants Mastering Islamic Finance training based on therecommendation of General of Budget Financing and Risk Management
Manajemen Pelatihan Pengantar Kerja di Pusdiklat Pegawai Kementerian Ketenagakerjaan
Authors: Hasanah Rora Irna , Matin Matin , Muhammad Amril
Published: February 2025

This study aims to determine the introductory training management at Ministry ofManpower Training and Education Center. In research on training management trainingfocused on the planning and implementation of training. This research is a qualitativedescriptive study. Determining the subject of this study using snowball sampling. Datacollection techniques used were interviews, observation and documentation. Data wereanalyzed by descriptive qualitative.The results of the study indicate that the introductorytraining management Employees working in the Ministry of Employment Training Centerinclude: 1) Planning training in with AKD (Training Needs Analysis) tailored to theneeds on the ground. Formulate the curriculum, syllabus, teaching materials, methods,schedules, and lecturer. After conducting a needs analysis phase, 2) The training beginswith a letter calling the membership then process the results of field organizersformulation of curriculum, syllabus and schedule to be processed into a tentativeschedule. Next is a learning process begins with classical training and learning outsidethe classroom there are street vendors (Practice Field work) in order to train theparticipants in terms of skills. After the stage of the learning process of the next stage isthe end of the training seminar is the last stage of determining graduation trainingparticipants were announced at the closing. Then follow-up after the participants followthe training is coaching and empowerment of the participants returned to the horse'smouth each work unit. Employee Training Center and related Technical Unit shouldprepare earlier and more intensively communicate in detail in preparing the training. theneed for alternative plans or concepts implementation and submitted directly to therelevant parties prior to the implementation of the training in order to anticipate atechnical error or adjustment situation and conditions on the ground so it does not needto re-coordination.
Evaluasi Program Mahasiswa Wirausaha (PMW) di Universitas Negeri Jakarta
Authors: Khiyari Nuwrile Ard , Arum Wahyu Sri Ambar , Zulaikha Siti
Published: February 2025

This research aims to give a description and information about EntrepreneurStudent Program (PMW) that has been held at Jakarta State University. This evaluationresearch uses Context, Input, Process and Product (CIPP) model with evaluativeapproach and descriptive method. Data were collected through observations, interviews,questionnaire, documentation study that have been done in Jakarta State University. Theresult of research shows Entrepreneur Student Program has been well done and met theevaluation criteria; 1) evaluation result in program background, goal and need analysishas met the evaluation criteria and shows good in category but legal basis of the programmanagement team should be made, 2) evaluation result in program human resources,objective and infrastructure of program has met the evaluation criteria but clearorganizational structure should be made and human resources who are committed andcompetent in program implementation, 3) evaluation result in program preparation,provision, business run, monitoring and evaluation has met the evaluation criteria but theprogram management team need to monitor the performance of mentor and monitoringand evaluation team so that goal of monitoring and evaluation be achieved with goodimplementation, 4) evaluation result in program result and report has met the evaluationcriteria but concrete efforts should be made to encourage the formation of organizationsthat specifically manages entrepreneurship program.
MANAJEMEN MUTU PENDIDIKAN DI SMA NEGERI 8 JAKARTA
Authors: Sibuea Moria Augusta , Listyasari Winda Dewi , Supadi Supadi
Published: February 2025

The study aims to obtain data in SMA Negeri 8 Jakarta which aims to know the quality of education management in SMA Negeri 8 Jakarta. This research was conducted from June 2017 until August 2017. Researcher used qualitative approaches and descriptive methods. Data collection was done through observation, interview, and documentation study. The sources of this research are: Deputy Headmaster of Public Relations Department as well as Responsible of Quality Management System ISO 9001: 2008, Head of School Administration Administration, and Teacher Representative as well as School Quality Internal Audit Team. The quality management planning of education in SMA Negeri 8 Jakarta starts from the preparation of the plan based on the evaluation result of the previous program. Planning is approved at the faculty meeting at the beginning of the school year. The planning process is guided by customer needs, vision, mission, and school goals, as well as government regulations. Implementation of quality management education at SMA Negeri 8 Jakarta involves every element in school according to the capacity and each part. In conducting the implementation of the school guided by the programs that have been agreed, the government regulation, as well as the quality objectives of SMA Negeri 8 Jakarta. Supervision of education quality management at SMA Negeri 8 Jakarta uses several strategies to conduct supervision that is using supervision instrument, customer satisfaction questionnaire learners to program in each school operational area, monitoring activity of OSIS-PK, and so on.
 
Keywords: Total Quality Management (TQM), Planning, Implementation, Supervision.
Amplifying Lived Expertise on “Food Is Medicine” in the Mississippi Delta’s Legacy of Racism
Authors: Nicholson-Robinson Vanessa , Krobath Danielle M. , Dixit-Joshi Sujata , Hawkins Cassandra , Miller Julian , Schultz Daniel J. , Economos Christina
Published: February 2025

For generations, Mississippi Delta residents have been subjected to food inequity and resource deprivation from centuries of racism. The Food Is Medicine (FIM) movement is gaining salience as one solution to address diet-related health conditions in partnership with health care providers, medical systems, and local agriculture groups.

The Delta GREENS (Growing a Resilient, Enriching, Equitable, Nourishing food System) FIM research study conducted focus groups in July and August 2023 to center the perspectives and lived expertise of residents in the Mississippi Delta receiving health care services from the Delta Health Centers.

This analytic essay provides context of the past and present food and farming infrastructure in the Mississippi Delta from the residents of these communities. The goal is to inform equitable and sustainable FIM interventions in the rural South and elsewhere in the country among historically marginalized populations. ( Am J Public Health. Published online ahead of print February 6, 2025:e1–e8. https://doi.org/10.2105/AJPH.2024.307937 )