bluuebunny/crossref_metadata_2025 huggingface dataset:
Interrelación entre el derecho laboral, derecho de incidencia colectiva y el derecho cooperativo. Estudio de caso
Authors: Yorg José Alberto , Ramírez Zarza Ana María
Published: December 2018

En el presente trabajo analizamos un caso que pone su foco, con un método narrativo, interpretativo y reflexivo, sobre acontecimientos de dos docentes cooperativos, maestros de grado, que invocan Derechos Adquiridos en base a situaciones devenidas de la convocatoria realizada desde el Ministerio de Cultura y Educación de la Provincia de Formosa-Argentina —desde el año de 1996 hasta nuestros días—. Se examina la peculariedad de la tensión surgida del trastocamiento del Derecho Constitucional de enseñar y aprender cooperativismo, inescindible al desempeño y la incumbencia profesional de los educadores, como expresión de la doctrina que resalta la relación que hay entre los derechos individuales y sociales, verbigracia. En ese contexto se entrelazan, de manera amigable el Derecho Laboral, el Derecho de incidencia pública y el Derecho Cooperativo.Recibido: 20 junio 2018Aceptado: 10 octubre 2018Publicación en línea: 21 diciembre 2018
La participación económica de los socios cooperativos: cooperativas tradicionales, autogestionarias y cogestionarias de Costa Rica
Authors: Sánchez Boza Roxana
Published: December 2018

Costa Rica mantiene su ley cooperativa que data de 1968, con algunas reformas que no han cambiado su letra en cuanto al tratamiento de los Principios Cooperativos. La legislación cooperativa se ha enriquecido, en las últimas décadas, con la participación de la Procuraduría General de la República, de los tribunales y sobre todo con el análisis de la Ley cooperativa, realizado por el Instituto Nacional de Fomento Cooperativo, en su tarea de aclarar las dudas que los entes cooperativos y los cooperativistas le plantean, como producto de su vida diaria en sus organizaciones cooperativas. Con base en las fuentes mencionadas se comunica la posición de la legislación cooperativa costarricense frente al tercer Principio Cooperativo relacionado con la participación económica de los socios, según las diferentes partes que tiene ese principio y cómo afecta la relación de los asociados con la cooperativa, así como los derechos que derivan de la misma, en el campo económico.Recibido: 31 mayo 2018Aceptado: 17 septiembre 2018Publicación en línea: 21 diciembre 2018
La participación económica de los socios en las empresas cooperativas mexicanas
Authors: Izquierdo Muciño Martha E.
Published: December 2018

El tercer principio cooperativo es uno de los más importantes de los reconocidos por la Alianza Cooperativa Internacional, toda vez que habla del capital social y la forma como debe integrarse a través de los socios, describe la manera como éstos deben invertir en su cooperativa y como deben distribuir sus excedentes, reforzando con ello la necesidad y el deber de que los miembros contribuyan con capital para su propio negocio y además lo hagan con justicia y equidad. Sin embargo se observa que actualmente en muchos países las empresas cooperativas se abren cada vez más al mercado, ampliando el margen de sus operaciones con capital de riesgo e incorporando la participación de inversores no usuarios o no socios al capital social de las empresas, llegando en ocasiones a permitir que la distribución de resultados se haga en función de las aportaciones económicas y no por el ejercicio de la actividad cooperativizada, violándose con ello los principios de igualdad, equidad y solidaridad.Recibido: 21 mayo 2018Aceptado: 24 septiembre 2018Publicación online: 21 diciembre de 2018
There is Nowhere to Hide: Spirit and Heart in Afro-Indigenous Transformative Engagement
Authors: Henay Charlotte
Published: December 2018

An Introduction to the Special Issue
Walking the Path of My Ancestors: The Siksikastiapi (Blackfoot Confederacy)
Authors: Prete Tiffany
Published: December 2018

This article articulates myself and my community’s journey navigating the Oblates of Mary Immaculate (OMI) records written historically about our People (the Bloods) in order to identify who our ancestors are. Through the examination of historical texts, records and materials written by the Oblate missionaries of North-Western Canada, we were able to discover the hidden lived experiences of our People. The purpose of this study was to provide new scholarly insights into the texts and records of the Oblates regarding the Blood People. This research took place at the Alberta Provincial Archives over a seven-month period. This article reviews who the Oblates of Mary Immaculate were, and what measures were used to uncover our ancestors in the Provincial Archives. Data analysis determined that the individual archival records fragmented Indigenous Peoples and their history; however, collectively these records blend together to tell a story.
I am the emu
Authors: Hogarth Melitta
Published: December 2018

An ink drawing and verse describing Melita Hogarth's story as one of the emerging narratives in Indigenous history and the efforts of the Aboriginal peoples in Australia to claim their identity and place in the land.
Researching, Planning, and the Implementation of Tāłtān Language Nests: Sharing our Experiences
Authors: Thompson Edōsdi / Judy , Dennis Gileh / Odelia , Louie Shāwekāw / Patricia
Published: December 2018

Since 2012, our nation has been working to revitalize and reclaim our language, with an emphasis on the creation of new speakers. Tahltan Elders have spoken about the importance of our young children learning our language, so a focus has been on teaching babies and toddlers in language nests. A language nest is a home-like environment for infants to learn the language in an immersion setting and provides opportunities for all generations to be part of the revitalization of a language. One of the authors carried out research that focused on Tahltan community experiences of language revitalization. The investigation focused on language revitalization’s connection to health and healing and what needs to be done to revitalize our language. Following recommendations from that research, language nests have been one of the vital components our Language and Culture Program has focused on. The ways in which community members in Tahltan communities have planned and implemented language nests will be discussed, along withe sharing experiences and activities that are currently being carried out.
Where is Cultural Safety in Education?
Authors: Smith Mary , Spadoni Michelle , Kioke Sandra
Published: December 2018

Three nurse researchers came together in 2015 to conduct a study focusing on Indigenous learning within a Nurse Practitioner program in Canada. This work unfolds here as a series. The first, brings to the fore the researchers’ relationship with the research answering the question “Who am I in relation to the Research?” This is followed by an account of the research, “A call to action: Faculty perspectives of cultural safety within a nurse practitioner curriculum.” Coming to know the researchers’ experiences within the context of nursing education, practice and their personal life experiences became a vital activity, one that would drive and instigate the overall research endeavour. Through this integral process the researchers functioned also as participants where analysis was both self-interpretative and hermeneutic. Preunderstandings molded through societal, cultural and historical forces interconnected with meanings of Indigenous methodology. Unearthing root assumptions through critical dialogues and stories was found to illuminate embedded world-views that challenged pervasive colonial perceptions critical to understanding the interwoven nature of cultural safety and reconciliation. This writing may be of high interest for researchers and educators wishing to create and sustain culturally safe spaces in practice and learning environments.
Cedar, Tea and Stories: Two Indigenous Women Scholars Talk About Indigenizing the Academy
Authors: Brulé Elizabeth , Koleszar-Green Ruth
Published: December 2018

In an effort to redress the educational needs of Indigenous peoples as part of the Truth and Reconciliation Commission of Canada’s call to action (2015), two Indigenous colleagues, Elizabeth Brulé and Ruth Koleszar-Green, came together to engage in a collective reflection on what Indigenizing the curriculum has meant to each of them. Through a collective dialogue that affirms that knowledge is created through our individual and collective storytelling, they discussed the challenges and successes that Indigenous women have encountered in their attempts to indigenize the curriculum over the past decade in the province of Ontario, Canada. Collaborative work such as this has not only provided them with an enriching intellectual and collective experience but has also given them cause for hope in their pursuit for truth and reconciliation. Through this collective dialogue, issues of Indigeneity, pedagogy, reconciliation and sisterhood are discussed.
Viola Desmond’s Canada: A History of Blacks and Racial Segregation in the Promised Land
Authors: Butler Jodi
Published: December 2018

Book review of Graham Reynold's 2016 history of Black Canadians in Nova Scotia with an account of Anti-Black oppression and Black resistance in Canada.
Optimization Improved K-Means on Centroid Initialization process using Particle Swarm Optimization for Tsunami Prone Area Groupings
Authors: Santika Gayatri Dwi , Sari Nadia Roosmalita , S M Zaki , Mahmudy Wayan Firdaus
Published: December 2018

Tsunami is a high wave caused by tectonic earthquakes, volcanic eruption or landslides in the ocean.  Indonesia is one of the countries that has thousands of islands. Lots of towns is a city on the banks or waterfront city. Indonesia becomes Tsunami prone areas. Tsunami can affect damage in various sectors, namely land degradation and infrastructure, environmental damage, fatalities, even the psychological impact on the victims themselves. Therefore, it takes a clustering of tsunami-prone areas. The result of clustering can give information to the public to remain alert to the danger of the tsunami. Also, clustering of the tsunami can be used by a government to prepare policies in overcoming the danger of the tsunami. Improved K-Means is an approach that proposed in this study to clustering the tsunami prone areas. In selecting the initial centroid must be done properly to produce a high accuracy. We proposed a method to determine the initial centroid appropriately, so that can increase the accuracy. The proposed method is Particle Swam Optimization (PSO). This study also uses comparison methods, such as K-Means, K-Means Improved, and K-Means Improved PSO. This study uses silhouette coefficient to test the accuracy of the system. The result showed that the proposed method has higher accuracy than the comparison method. Silhouette coefficient generated at 0.99924223 with smaller computing time
Digital Teaching: In Search Of An Effective Paperless Platform For Classroom Activities
Authors: Dieck-Assad Flory Anette
Published: December 2018

Sydney J. Harris advises us, “The whole purpose of education is to turn mirrors into windows”. Never like today, are we in the need to help teachers and professors to guide their students to open windows and get involved with the geopolitical and economic needs of the world. This paper tests the hypothesis that Microsoft OneNote Class Notebook (MONCN), used in undergraduate Finance courses as a tool for digital teaching, can both promote sustainable development and make the students become leaders, using this innovative tool of learning as part of their own activities and lives in the future. The test of the hypothesis also demonstrates that students manage to make the classroom time more effective and efficient for learning when using MONCN as a paperless technological platform. Thus, without impacting the effectiveness and quality of education, MONCN surges as a tool for inspiring the students to become committed citizens that can change the world and collaborate in the fight of climate change.
O cuidado prestado por doulas em uma maternidade p�blica: o olhar das pu�rperas
Authors: Borja Thayana Jovino , Freitas Wagl�nia De Mendon�a Faustino e , Santos Larissa Sales dos , Nascimento Bruna Grasiele da Silva , Lima D�bora Rodrigues Alves de , Silva Jessyka Cibelly Minervina da Costa
Published: December 2018

Objetivo: Analisar a percep��o das mulheres sobre o cuidado prestado por doulas durante o trabalho de parto, o parto e p�s-parto imediato em uma maternidade p�blica de Jo�o Pessoa - PB. M�todo: Estudo explorat�rio, descritivo, com abordagem qualitativa, realizado com oito pu�rperas, aprovado pelo Comit� de �tica em Pesquisa do CCS/UFPB, sob parecer 808.256. O material emp�rico foi produzido por meio de entrevistas semiestruturadas e analisado pela t�cnica de an�lise do discurso de Fiorin. Resultados: As pu�rperas compreendem o trabalho da doula como adjuvante para diminui��o da dor e desconforto no trabalho de parto e no parto. Enunciaram que o v�nculo estabelecido contribuiu para tornar o parto um momento positivo e afetuoso. Conclus�o: O cuidado prestado pela doula promoveu experi�ncias exitosas no trabalho de parto, no parto e no p�s-parto, favorecendo o protagonismo da parturiente e contribuindo para que fosse uma experi�ncia satisfat�ria.
On almost \(s-\)topological vector spaces
Authors: Ram Madhu , Sharma Shallu , Billawria Sahil , Hussain Amjad
Published: December 2018

In this paper, we introduce the notion of almost \(s-\)topological vector spaces and present some examples and counterexamples of almost \(s-\)topological vector spaces. Some general properties of almost \(s-\)topological vector spaces are investigated.
Seroprevalence of mumps and its association with some social determinants in Manisa Province, 2014
Authors: SAĞLAM Yasin , ÖZBEK Özgen Alpay , İŞLEK Duygu , HEKİMOĞLU Can Hüseyin , DEMİRPENÇE Nur , EMEK Mestan , ÇAVUŞ Sema Alp , ATASOYLU Gonca , ÖKTEM İbrahim Mehmet Ali , ÜNAL Belgin
Published: December 2018

Aims: The
aim of this study was to determine the seroprevalence of mumps and its
association with some social determinants of health in the Manisa Province. Method: A
random sample of individuals, aged two years and over, from the Manisa Province
was included in this cross-sectional study (n=1740). Individuals were
interviewed and blood samples were taken in family health centres. Specific
antibodies were analysed using the anti-mumps virus ELISA IgG test and values
of ≥22 IU/mL were considered as positive. Results: Overall mumps seropositivity was found to be 80.3%.
Furthermore, seropositivity was 72.5% for ages 2-19 and 83.1% for ages over 20
(p<0.01). The Odds Ratio of mumps seropositivity was 1.42 (0.94-2.08) for
people who had an annual equivalent income per capita of more than 5692 TL; and
OR = 1.23 (0.54-2.82) for people who were living in homes which had fewer than
one person per room.
Conclusions: In
all age groups, there is between 10-20% of the population sensitive to the risk
of a mumps epidemic. There is no statistically significant association between
mumps seropositivity and social determinants. For a successful mumps control
program, high vaccine coverage should be aimed and maintained.
Uso del vídeo como recurso educativo no formal en la docencia universitaria en ingeniería informática = Use of video as a non-formal educational resource in higher education teaching in computer engineering
Authors: Borrás Gené Oriol
Published: December 2018

ResumenEl extenso programa curricular de las asignaturas, en los actuales programas de grado, y las actividades asociadas suponen una limitación temporal para el docente a la hora de impartir de manera precisa los contenidos de asignaturas técnicas en grados de ingeniería, que requieren además la resolución de problemas y la dedicación de horas de laboratorio enfocadas a la realización de prácticas.Para el caso concreto de asignaturas de primer año supone un reto adicional la adaptación del estudiante que proviene de enseñanzas medias, y necesita de una mayor guía por parte del docente. Esta experiencia expone una práctica docente cuyo objetivo principal ha sido actuar en tiempo real, sobre las necesidades de los estudiantes, que cuentan con conocimientos heterogéneos, a la vez que mejorar los resultados académicos de la asignatura, que exige unas competencias básicas de pensamiento computacional de las que carecen los estudiantes.Para alcanzar este objetivo se ha optado por el uso del vídeo como refuerzo a la práctica docente, a través de un lenguaje y medio no formal como es la plataforma YouTube. Los resultados de la asignatura y en concreto el uso de los vídeos han mostrado un buen grado de una aceptación para los alumnos que los utilizaron a lo largo de toda la asignatura y una percepción de aprendizaje notable, además de obtener unos resultados satisfactorios en el número de alumnos que superaron la asignatura.AbstractThe broad curricular program of the subjects, in the current degree programs, and the associated activities suppose a temporary limitation for the teacher at the time of teaching more accurately the contents of technical subjects in degrees of engineering, which also require the resolution of problems and the dedication of laboratory hours focused on the realization of practices.For the specific case of first year subjects, it is an additional challenge to adapt the student that comes from middle school, and needs more guidance from the teacher. This experience exposes a teaching practice whose main objective has been to act in real time, on the needs of the students, who have heterogeneous knowledge, at the same time as improving the academic results of the subject, which demands some basic computational thinking skills of those that students lack.To achieve this goal, the use of video has been chosen as a reinforcement to the teaching practice, through a non-formal language and means, such as the YouTube platform. The results of the subject and in particular the use of the videos have shown an acceptance for the students who used them throughout the course and a remarkable learning perception, in addition to obtaining satisfactory results in the number of students who passed the subject.
LAW ASPECT IN TREATING ILLEGAL MINING CASE OF MINERAL C IN PATI REGENCY
Authors: Suyoto S , Hartanto Dwiyana Achmad
Published: December 2018

The research entitled "Law Aspect in Handling Illegal Mining Case of Mineral C in Pati Regency" is motivated by the increasing illegal mining of mineral C. It causes environmental damage, air pollution, licensing violation and tax. The research focus is limited to: (1) What are the influencing factors of illegal mining of mineral C in Sourthern Kendeng and Northern Kendeng mountains in Pati regency? (2) How to treat illegal mining case of mineral C in illegal areas of Southern Kendeng Mountain Area and Northern Kendeng Mountains in Pati Regency ? It applies sociological juridical approach. The results of the research showed: (1) Factors affecting illegal mining of mineral C in illegal areas of Southern Kendeng Mountain and Northern Kendeng Mountains include legal culture, legal structure and legal substance; (2) The treatment of illegal mining cases in the Southern Kendeng Mountains Area and the Northern Kendeng Mountains are conducted both penal and non penal.Keywords: Treatment, Mineral C, Illegal, Pati Regency
DISTINGUISHING CONSTITUTIONAL AND STATUTORY INTERPRETATION IN JUDICIAL REVIEW CASES: A BLURRED BOUNDARY LINE
Authors: Bisariyadi B
Published: December 2018

The establishment of the Constitutional Court to hold power of reviewing the constitutionality of Laws raises discourse on the distinction between constitutional interpretation and statutory interpretation. In judicial review cases, the separation, either in common law or civil law tradition, between the two interpretations is not clearly distinguished. The Indonesian Constitutional Court, in judicial review decisions, shows that the Court does not only interpret constitutional provision. In a number of decisions, the Court has put more emphasis on the use of statutory interpretation. The essay discusses the Constitutional Court practice in the use of constitutional interpretation and statutory interpretation on judicial review cases.Keywords: Constitutional Court, judicial review, constitutional interpretation, statutory interpretation.
Democracia: Criação de direitos
Authors: Chauí Marilena
Published: December 2018

Procuramos aqui marcar a diferença entre a concepção liberal da demo­cracia como regime político e aquela que toma a democracia como uma forma­ção social aberta aos conflitos e à criação de direitos. Essa ideia da democracia encontra dois grandes obstáculos no Brasil, quais sejam, a estrutura autoritária da sociedade brasileira e a implantação da economia política neoliberal.
Aristóteles sobre os fundamentos éticos e os fins do Estado
Authors: Ricken Friedo
Published: December 2018

Segundo Aristóteles reunir-se em comunidade política (Estado) per­tence à natureza humana. Sua finalidade não pode ser senão contribuir para o bem comum dos indivíduos que a compõem, cujo fim é a virtude. O Estado promulga leis que prescrevem os comportamentos próprios das diversas virtu­des. Ora, a justiça, enquanto disposição habitual de praticar o direito significa querer cumprir as leis e a igualdade de todos. Neste sentido, ela abarca todas as virtudes. A lei é uma aplicação da constituição. Esta define o governante e o fim do Estado, que é o critério para avaliar os diferentes tipos de constituição. Uma constituição será justa na medida em que promova o bem comum e não o bem do governante, não, porém, em termos ideais. De fato, a virtude consiste num meio termo entre extremos, de modo que a constituição deve prescrever o que é possível para a maioria dos cidadãos e para a maioria dos Estados, visando à igualdade entre os seus membros. De fato, porém, há três grupos em cada Estado, os muito ricos, os muito pobres e os que possuem medianamente. Os dois primeiros grupos, enquanto levados pela ambição ou pela inveja, são causa de distúrbios e divisões. A melhor constituição será a que mais contribui para o crescimento da “classe média”, como fator de equilíbrio nas decisões do Estado.
Ambiguidades do julgamento moral da política: uma crítica hegeliana
Authors: Dela-Sávia Sérgio
Published: December 2018

Nosso interesse é considerar a amplitude política que pode assumir a crítica hegeliana da moralidade subjetiva. Sabemos que esta não é circunstancial e tampouco anódina na obra de Hegel. Ludwig Siepp nota, com acerto, que a crítica hegeliana à moralidade, tanto na Fenomenologia do Espírito como nos Princípios da Filosofia do Direito, “mantém uma relação central com sua com­preensão da realidade” (2013, p. 183). Entretanto, embora momento fundamental no processo de mediação da liberdade, a posição moral, na medida em que se revela, na sua abstração formal, idêntica ao Bem que deve ser, mostra-se ambígua quanto à extensão de sua legitimidade. Esse equívoco é ainda mais problemático quando fazemos dela princípio de julgamento da ação política. Nossa posição é a de que essa extrapolação transfere para o campo do político o equívoco decorrente da dialética mesma da moralidade. Consideremos, primeiramente, o lugar que ocupa a moralidade no plano da Filosofia do Direito e seus limites críticos para, em seguida, examinarmos o problema decorrente da subsunção da política pelo julgamento moral.
KONSTRUKSI UJI KESESUAIAN MODEL GEOGRAPHICALLY WEIGHTED POLYNOMIAL REGRESSION
Authors: Chamidah Nur
Published: December 2018

AbstractGeographically Weighted Polynomial Regression (GWPolR) is a generalization of   Geographically Weighted Regression (GWR) model. By using the generalization, GWPolR has parameters much more than GWR model. In general, excess of the number of parameter will have a higher appropriate value. However, the model which has less parameter will have the excess for easing in application and its interpretation. Nevertheless, when the model has more the parameters, then the model will be better significantly to be used.  Therefore, the aim of this paper is to construct the conformity between hypothesis test with respect to the GWPolR model. Keywords: Geographically weighted polynomial regression, Geographically Weighted Regression, uji kesesuaian model AbstrakGeographically Weighted Polynomial Regression (GWPolR) merupakan perumuman dari model Geographically Weighted Regression (GWR). Dengan perumuman tersebut, model GWPolR memiliki jumlah parameter yang lebih banyak daripada model GWR. Umumnya, kelebihan model dengan jumlah parameter lebih banyak adalah memiliki nilai kesesuaian lebih tinggi. Sebaliknya, model dengan jumlah parameter yang sedikit memiliki kelebihan berupa kemudahan dalam aplikasi dan interpretasinya. Namun demikian, jika model dengan jumlah parameter yang lebih banyak ternyata secara signifikan lebih baik maka sudah seharusnya model tersebut dipilih untuk digunakan. Oleh karena itu, tujuan paper ini adalah mengkonstruksi uji hipotesis kesesuaian model GWPolR. Kata Kunci:    Geographically weighted polynomial regression, Geographically Weighted Regression, uji kesesuaian model
Pengembangan Modul PreprocessingTeks untuk Kasus Formalisasi dan Pengecekan Ejaan Bahasa Indonesia pada Aplikasi Web Mining Simple Solution (WMSS)
Authors: Chuzaimah Zulkifli Umi
Published: December 2018

Abstract Data of social media currently has been much used to analyze both sentiment analysis and another analysis. In fact, data that is obtained from the social media in generally has some mistakes which can influence the spelling in writing of words. The solution offered is word formalization and spelling check. Based on the problem, it will be built a preprocessing model to overcome two the mistakes. The method that will be used in formalization is to change the words to be formal form based on KBBI, while the method  used  for spelling check is spelling correction. Spelling correction method consists of distance edit, bigram and distance edit rule. In this study, in addition the application of both methods, also it will be analyzed comparing the result of spelling correction. From the result of analysis shows that distance edit rule has higher accuracy, namely 83.39% than using both edit distance and bigram method. In addition, edit distance rule method also has faster performance than another both methods. Overall, method to change word to formal word were based on KBBI and spelling correction has been able to overcome the problem of two cases, such that it can increase accuracy of  the result of the analysis. Keywords: preprocessing, spelling correction, edit distance, bigram AbstrakData media sosial saat ini telah banyak digunakan untuk melakukan analisis baik analisis sentimen maupun analisis terkait lainnya. Nyatanya, data yang diperoleh dari media sosial tersebut pada umumnya memiliki kesalahan yang akan mempengaruhi hasil analisis. Kesalahan tersebut berupa penggunaan kata yang tidak baku dan adanya kesalahan ejaan dalam penulisan kata. Solusi yang ditawarkan berupa formalisasi kata dan pengecekan ejaan. Berdasarkan masalah tersebut, akan dibangun modul preprocessing untuk mengatasi dua kesalahan di atas. Metode yang digunakan pada formalisasi adalah mengubah kata ke bentuk formal berdasarkan KBBI sedangkan metode yang digunakan pada pengecekan ejaan adalah spelling correction. Metode spelling correction tersebut terdiri dari tiga yaitu edit distance, bigram dan edit distance + rule. Pada penelitian ini, selain penerapan kedua metode juga akan dilakukan analisis untuk melihat perbandingan hasil pada metode spelling correction. Dari hasil analisis tersebut, diketahui bahwa metode edit distance + rule memiliki akurasi yang lebih tinggi yaitu sebesar 83,39% dibandingkan dengan kedua metode lainnya yaitu edit distance dan bigram. Selain itu, metode edit distance + rule juga memiliki performa tercepat dibandingkan kedua metode lainnya. Secara keseluruhan, metode mengubah kata ke bentuk formal berdasarkan KBBI dan spelling correction telah mampu mengatasi masalah pada dua kasus di atas sehingga dapat meningkatkan akurasi hasil analisis. Kata Kunci:preprocessing, spelling correction, edit distance, bigram
Effects of anesthetic technique on postoperative pulmonary metastasis in patients undergoing laryngectomy
Authors: Huang Xuanwei , Wang Xudong , Lai Jielan , Deng Kun , Lu Yali , Lai Renchun
Published: December 2018

Background: Whether laryngeal cancer is directly implanted into the lungs through the respiratory tract during orotracheal intubation remains unclear. The present study aimed to determine whether orotracheal intubation was an independent risk factor for postoperative pulmonary metastasis, recurrences and survival in patients undergoing laryngectomy.
Methods: Medical records between January 1, 2006 and December 31, 2016 were reviewed. Patients who underwent orotracheal intubation (intubation group) were matched 1:1 with those who received tracheotomy (tracheotomy group) during the induction of general anesthesia. The primary outcome was postoperative pulmonary metastasis. Secondary outcomes included local recurrences, lymphatic metastasis and overall survival. Data were analysed by Kaplan-Meier curves, log-rank test, hazards regression and Cox regression.
Results: Comparing the tracheotomy group and orotracheal intubation group, no statistically significant differences were found in postoperative pulmonary metastasis (P = 0.688), local recurrence (P = 0.215), lymphatic metastasis (P = 0.480) and all-cause death (P = 0.299). Primary cancer site was an independent risk factor for pulmonary metastasis [hazard ratio (HR) 0.29, 95% confidence interval (CI) 0.13-0.68; P = 0.013] and local recurrence (HR 2.69, 95% CI 1.39-5.21; P = 0.003). Unexpectedly, postoperative chemotherapy was an independent risk factor for lung metastasis (HR 7.58, 95% CI 3.11-18.47; P < 0.001) and lymphatic metastasis (HR 5.18, 95% CI 2.57-11.91; P < 0.001). Five-year overall survival was not associated with anesthetic technique (P = 0.473).
Conclusions: This retrospective study suggested that orotracheal intubation during laryngectomy was not a risk factor for postoperative pulmonary metastasis, local recurrence and overall survival.
Keywords: Anesthetic technique, Postoperative pulmonary metastasis, Laryngectomy
Multiplex Polymerase chain reaction to diagnose bloodstream infections in patients after cardiothoracic surgery
Authors: Pilarczyk Kevin , Rath Peter-Michael , Steinmann Jörg , Thielmann Matthias , Dürbeck Maximillian , Padosch Stephan A. , Jakob Heinz G. , Dusse Fabian
Published: December 2018

Background: Sepsis and other infectious complications are major causes of mortality and morbidity in patients after cardiac surgery. Whereas blood culture (BC) as the current diagnostic gold standard suffers from low sensitivity as well as a reporting delay of approximately 48–72 h, polymerase chain reaction (PCR) based technologies might offer a fast and reliable alternative for detection of bloodstream infections (BSI). The aim of this study was to compare the performance of real time multiplex-PCR “SeptiFast” (SF), a real-time multiplex PCR assay, with conventional BC testing in patients after cardiac surgery.
Methods: 279 blood samples from 168 individuals with suspected BSI were analyzed by SF and BC. Receiver operating characteristic (ROC) curves were generated to determine the accuracy of clinical and laboratory information for the prediction of positive SF results.
Results: Excluding results attributable to contaminants, 14.7% (n = 41) of blood samples were positive using SF and 17.2% (n=49) using conventional BC (p= n.s.). In six samples, SF detected more than one pathogen. Among the 47 microorganisms identified by SF, only 11 (23.4%) could be confirmed by BC. SF identified a significantly higher number of Gram-negative bacteria than BC (28 vs. 12, χ2=7.97, p=0.005). The combination of BC and SF significantly increased the number of detected microorganism, including fungi, when compared to BC alone (86 vs. 49, χ2=13.51, p<0.001). C-reactive protein (CRP) (21.7±11.41 vs. 16.0±16.9 mg/dl, p=0.009), procalcitonin (PCT) (28.7±70.9 vs. 11.5±30.4 ng/dl, p=0.015) as well as interleukin 6 (IL 6) (932.3±1306.7 vs. 313.3±686.6 pg/ml, p=0.010) was significantly higher in patients with a positive SF result. In addition, incidence of severe acute kidney injury (AKI) was higher in SF positive than in SF negative patients (31/42 [76%] vs. 125/237 [53%], p=0.01). Using ROC analysis, IL-6 (AUC 0.836) as well as CRP (AUC 0.804), but not PCT showed the best predictive values for positive SF results. Microbiological diagnostic information gained through SF led to 8 therapy adaptations.
Conclusion: The real time PCR-based SF test might represent a valuable addition to the traditional BC method for rapid etiologic diagnosis of BSI in patients after cardiothoracic surgery. This powerful method furthermore applies in particular for individuals with fungal infections, Gram-negative bacteremia, AKI and/or elevated CRP and IL-6-concentration. However, due to the low performance in detecting Gram-positive pathogens and the inability to determine antibiotic susceptibility, it should always be used in combination with BC. [1]
Key words: Blood stream infection, blood culture, real time multiplex Polymerase Chain Reaction
Comparative Study between Modified William's Airway (Fekry Airway) versus the U Shaped Guedl's Airway as Assisted Device for Fiber Optic Intubation: A Randomized Controlled Trial
Authors: Mohamed Ahmed Abdalla , Mahmoud Sherin Refaat , Youssef Maha Mohamed Ismail , Dobal Nasser Mohamed , Zoheir Heba Alla Hussein , Hady Hany Mohamed El , Elbadawy Ahmed Mohamed , Khair Tamer Mohamed , Belita Mohamed Ibrahim , Atta Ehab Mohi , Seleem Ahmed Abd EL Aziz , Osman Safinaz Hassan , Fahmy Rania Samir , Abdelrahman Reham Ali , Salem Ahmed Essam
Published: December 2018

The authors have removed this preprint from Research Square.
A Short‐term Study to Compare Field Strategies for Ammonia Emission Mitigation
Authors: Yagüe María R. , Valdez Alcira S. , Bosch‐Serra Àngela D. , Ortiz Carlos , Castellví Francesc
Published: December 2018

Abatement of NH3 emissions is crucial in calcareous soils under semiarid Mediterranean climates. The aim of the study was to compare NH3 emissions using different slurry application methods. An experiment was performed on a clay loam soil to evaluate NH3 emissions before sowing and at winter cereal tillering. Pig slurry was applied using two methods, one that applied slurry by splashing it over a plate (SP), and another that applied slurry in strips using trail hoses (TH). Emissions were measured using semi‐static chambers at variable intervals for 12 to 13 d (315.5 h for sowing and 287 h for tillering). Maximum NH3 flux emissions were always observed during the earliest period of measurements after slurry spreading (3.5–5 h). Before sowing, regardless of the method, accumulated NH3 losses (during 315.5 h) ranged between 2 and 3 kg NH3–N ha−1 because of the low dry matter content of the slurry (<2%), which enhanced infiltration. Losses represented about 2 to 3% of the total N applied. At cereal tillering, average accumulated losses of NH3 (during 287 h) were 1.7 kg N ha−1 using TH (1.1% of total N applied) and were as high as 5.4 kg N ha−1 (3.2% of total N applied) using SP. Because N topdressing is recommended as a measure to increase its efficiency, TH is recommended over SP. Thus, this short‐term study concludes that TH may reduce NH3 emissions in semiarid environments. Further study of these strategies is recommended under different climate and soil conditions.

Core Ideas

NH3 emissions from slurry splash plate (SP) spreading can be <4% of the NH4+ applied.

Trail hoses (TH) reduce NH3 emissions from slurries versus SP at cereal tillering.

At sowing, low slurry dry matter bridges the gap in NH3 emissions between TH and SP.
Knowledge management, adaptability and business process reengineering performance in microfinance institutions
Authors: Nkurunziza Gideon , M. Ntayi Joseph , C. Munene John , Kaberuka Will
Published: December 2018

The purpose of this paper is to provide theoretical explanation of business process reengineering performance using emerging themes of adaptability and knowledge management in the context of developing economies. The study used a narrative cross-sectional survey conducted using qualitative data collection technique, specifically the appreciative inquiry. The study used operations managers and senior executive managers to gather qualitative data from Uganda’s reengineered microfinance institutions to provide indepth explanation of business process reengineering performance. The authors find that adaptability, knowledge creation and knowledge sharing explain business process reengineering performance. The results suggest that business process reengineering be made mandatory to ensure sustainable competitiveness of the financial sector. The study provides novel insights of business process reengineering performance using a theory of change and a complexity theory. Methodological, theoretical, managerial and policy implications herein play pivotal role in bridging the knowledge gap that exists in Microfinance institutions of developing economies.
Apoio das Universidades aos Spin-Offs Acadêmicos nas Fases de Early e Later Stage
Authors: Cabanne Cibele Lopes Souto Maior , Oliveira Xênia L’amour Campos , Teixeira Rivanda Meira
Published: December 2018

Pesquisas sobre spin-offs acadêmicos demonstram diferentes tipos de apoio prestado pelas universidades nas fases de desenvolvimento early e later stage. Este estudo tem como objetivo analisar as formas de apoio concedido pelas universidades aos spin-offs acadêmicos nessas fases de desenvolvimento. Foi realizado um estudo de casos múltiplos com dois spin-offs acadêmicos, um de universidade pública e outro de universidade privada, localizados na cidade de Aracaju, no Estado de Sergipe. Os spin-offs acadêmicos foram selecionados em função da fase de desenvolvimento, um deles com menos de quatro anos de criação (early stage), e outro com mais de quatro anos (later stage). Pode-se observar que o apoio fornecido pelas universidades aos spin-offs analisados foi considerado deficiente nas duas fases. Dessa forma, não foi observado participação ativa da universidade na obtenção de recursos, disponibilização de contatos ou oferta de disciplinas voltadas ao empreendedorismo. O mérito das universidades consistiu na disponibilização das incubadoras e, por meio delas, cursos de capacitação e infraestrutura. Sugere-se que é necessário conscientizar as universidades sobre a importância do estímulo ao empreendedorismo e do suporte da universidade aos primeiros anos do spin-off, que são os mais críticos.
N-MyristoylG-PseAAC: Sequence-based Prediction of N-Myristoyl Glycine Sites in Proteins by Integration of PseAAC and Statistical Moments
Authors: Khan Sher Afzal , Khan Yaser Daanial , Ahmad Shakeel , Allehaibi Khalid H.
Published: December 2018

N-Myristoylation, an irreversible protein modification, occurs by the covalent attachment of myristate with the N-terminal glycine of the eukaryotic and viral proteins, and is associated with a variety of pathogens and disease-related proteins. Identification of myristoylation sites through experimental mechanisms can be costly, labour associated and time-consuming. Due to the association of N-myristoylation with various diseases, its timely prediction can help in diagnosing and controlling the associated fatal diseases. Herein, we present a method named N-MyristoylG-PseAAC in which we have incorporated PseAAC with statistical moments for the prediction of N-Myristoyl Glycine (NMG) sites. A benchmark dataset of 893 positive and 1093 negative samples was collected and used in this study. For feature vector, various position and composition relative features along with the statistical moments were calculated. Later on, a back propagation neural network was trained using feature vectors and scaled conjugate gradient descent with adaptive learning was used as an optimizer. Selfconsistency testing and 10-fold cross-validation were performed to evaluate the performance of N-MyristoylG-PseAAC, by using accuracy metrics. For self-consistency testing, 99.80% Acc, 99.78% Sp, 99.81% Sn and 0.99 MCC were observed, whereas, for 10-fold cross validation, 97.18% Acc, 98.54% Sp, 96.07% Sn and 0.94 MCC were observed. Thus, it was found that the proposed predictor can help in predicting the myristoylation sites in an efficient and accurate way.
Non Nucleoside Reverse Transcriptase Inhibitors, Molecular Docking Studies and Antitubercular Activity of Thiazolidin-4-one Derivatives
Authors: Chitre Trupti S. , Patil Shital M. , Sujalegaonkar Anagha G. , Asgaonkar Kalyani D. , Khedkar Vijay M. , Garud Dinesh R. , Jha Prakash C. , Gaikwad Sharddha Y. , Kulkarni Smita S. , Choudhari Amit , Sarkar Dhiman
Published: December 2018

Background::

Management of Co-existence of Acquired immunodeficiency syndrome and Tuberculosis
has become a global challenge due to the emergence of resistant strains and pill burden.

Objective: :

Hence the aim of the present work was to design and evaluate compounds for their dual activity
on HIV-1 and Tuberculosis (TB).

Methods: :

A series of seven, novel Thiazolidin-4-one derivatives were synthesized and evaluated for their
anti-HIV and anti-tubercular activity along with Molecular docking studies. All the seven compounds displayed
promising activity against the replication of HIV-1 in cell-based assays. The four most active compounds
were further evaluated against X4 tropic HIV-1UG070 and R5 tropic HIV-1VB59 primary isolates. The
binding affinity of all the designed compounds for HIV-RT and Mycobacterium tuberculosis Enol Reductase
(MTB InhA) was gauged by molecular docking studies which revealed crucial thermodynamic interactions
governing their binding.

Results::

The CC50 values for the test compounds were in the range of, 15.08-34.9 μg/ml, while the IC50
values were in the range of 16.1-27.13(UG070; X4) and 12.03-23.64 (VB59; R5) μg/ml. The control drug
Nevirapine (NVP) exhibited CC50 value of 77.13 μg/ml and IC50 value of 0.03 μg/ml. Amongst all these
compounds, compound number 3 showed significant activity with a TI value of 2.167 and 2.678 against the
HIV-1 X4 and the R5 tropic virus respectively. In anti-mycobacterial screening, the compounds proved effective
in inhibiting the growth of both log phase and starved MTB cultures.

Conclusion: :

Compound 3 has been found to be active against HIV-1 as well as MTB.
Association Between Immunologic and Virologic Functioning and Health-Related Quality of Life Among People Living with HIV, Tehran, Iran
Authors: Ghodrati Saeed , Shahabinezhad Zahra , SeyedAlinaghi SeyedAhmad
Published: December 2018

Background:

With recent progress in the treatment of people living with HIV (PLWH) and their increased rate of survival, health-related quality of life (HRQoL) has become an important issue.

Objective:

In the present study, we aimed to investigate the association of current CD4 cell count, baseline CD4 cell count, nadir CD4 cell count, and plasma viral load with health-related quality of life in PLWH.

Methods:

Participants were 67 PLWH who were under the treatment of antiretroviral therapy (ART) in Imam Khomeini Hospital of Tehran, Iran in 2016. Participants were divided into the two groups with high and low levels of current CD4 cell count, baseline CD4 cell count, nadir CD4 cell count and plasma viral load. We used independent sample t-test for data analysis using SPSS 22 software.

Results:

Our results demonstrated that for current CD4 cell count, the group differences were significant for total scores of HRQoL (P=0.028), also in the components of physical functioning (P=0.032), role limitation due to physical health problems (P=0.006), and role limitation due to emotional problems (P=0.009). Our data analysis showed that for baseline CD4 cell count (P=0.62), nadir CD4 cell count (P=0.29), and viral load group (P=0.78), the differences were not significant for HRQoL.

Conclusion:

Knowing the association between current CD4 count and health-related quality of life, adherence to ART might be a motivator for PLWH to enhance their health-related quality of life.
An Unusual Case of Medullary Thyroid Carcinoma and A Revision of Current Literature
Authors: Cipri Claudia , Vescini Fabio , Torresan Francesca , Pennelli Gianmaria , Pelizzo Maria Rosa , Triggiani Vincenzo , Guastamacchia Edoardo , Grimaldi Franco
Published: December 2018

Background:

Medullary thyroid cancer (MTC) accounts for 5% of all thyroid cancers and
occurs either sporadically or in a hereditary pattern. Routine calcitonin (CT) measurement is suggested
for MTC screening in patients with nodular thyroid disease.

Patient Findings: A 45 years-old woman incidentally discovered, with neck ultrasound, the presence
of thyroid micronodules. Fine-needle aspiration (FNA) on thyroid prevailing nodule did not demonstrate
cellular atypia.

During follow-up, FNA was repeated on the previously analyzed nodule suspicious for Hürthle cell
nodule suspicious for follicular neoplasm and on another hypoechoic right nodule which showed cellular
atypia. CT was <2 pg/ml (normal values <18.2 pg/ml), anti-thyroid antibodies were positive and the
patient showed a normal thyroid function.

The patient also was diagnosed with primary hyperparathyroidism with an enlarged parathyroid gland
behind the right thyroid lobe. Therefore, she underwent total thyroidectomy and a selective parathyroidectomy
was performed.

Histology showed an encapsulated microMTC (pT1aNxMx) associated with diffuse C-cell hyperplasia
and lymphocytic thyroiditis. The neoplasm was positive for calcitonin and chromogranin A and negative
for thyroglobulin. A right parathyroid adenoma was also diagnosed. One month after surgery basal
and stimulated CT were <2 ng/ml. Genetic analysis did not reveal mutation of RET proto-oncogene.
Twelve months after surgery, neck ultrasonography, chest and abdomen computed tomography did not
demonstrated residual/recurrent disease with undetectable serum CT.

Conclusion:

In the literature, few MTC cases with normal serum CT have been reported. Although
MTC without elevated plasma CT is extremely rare, normal or low CT levels, do not entirely exclude
this diagnosis.
Prophylactic and Therapeutic Treatments' Effect of Moringa Oleifera Methanol Extract on Cryptosporidium Infection in Immunosuppressed Mice
Authors: El-Sayed Nagwa M. , Fathy Ghada M.
Published: December 2018

Background: As natural herbs and medicinal plants extracts are widely used as alternative treatments for different parasitic diseases, some have been tested on Cryptosporidium either in vitro or in vivo. This study assessed the prophylactic and therapeutic treatments' effect of Moringa oleifera (M. oleifera) leaves methanol extract on immunosuppressed-Cryptosporidium infected mice.

Methods:

The evaluation was carried out by Cryptosporidium oocysts count in fecal samples, histopathological changes in the intestinal tissues, determination of IFN-γ level in mice sera and measuring the antioxidant activity in the intestinal tissues.

Results:

Prophylactic treatment by M. oleifera extract lowered Cryptosporidium oocysts shedding from immunosuppressed-infected mice although there was no complete elimination of the parasite. However, therapeutic treatment induced a significant reduction in Cryptosporidium oocysts counts by 91.8% higher than that of the drug control (nitazoxanide) group (77.2%). Histopathologically, the intestinal tissues from immunosuppressed-Cryptosporidium infected mice showed loss of brush border with severe villous atrophy and extensive necrosis. M. oleifera prophylactic treatment induced a moderate improvement of the pathological changes. However, the villi in M. oleifera therapeutic treated mice retained their normal appearance with minimal inflammatory cells. It was observed that M. oleifera extract induced a significant upregulation of IFN-γ in both prophylactic and therapeutic treated groups compared to that of the infected untreated group. In addition, M. oleifera leaves extract exhibited a significant antioxidant activity by reducing the levels of Nitric Oxide (NO) and Malondialdehyde (MDA) and increasing Superoxide Dismutase (SOD) level in the intestinal tissues compared to those of the infected and drug controls.

Conclusion:

M. oleifera leaves extract has potent prophylactic and therapeutic activities against infection with Cryptosporidium.