bluuebunny/crossref_metadata_2025 huggingface dataset:
Interaction between service exercise and gender on field tennis service skills
Authors: Nugroho Novan Arum , Purnama Sapta Kunta , Riyadi Slamet , Syaifullah Rony
Published: October 2023

Purpose. The purpose of this study was to determine the interaction between service exercise and gender on field tennis service skills.
Materials and Methods. The population in this study were Faculty of Sports, Universitas Sebelas Maret students, totaling 85 male students and 27 female students. The sample used was 24 male students and 24 female students. Collecting data on tennis serve skills using the Hewitt Tennis Achievement Test. The skill of serving tennis in court tennis is the accuracy and constancy of a tennis player's serve to start the game and being able to be skilled in serving tennis. The number of hits/ball contact with the racket is 10 hits with the target. To test the statistical hypothesis, the Tukey test was used at a significance level of α = 0,05 using SPSS 25.
Results. The results of data analysis showed that at α = 0.05 a maximum value of 0.000 < α 0.05 was obtained , for service training a maximum average value of 28.79 was obtained and an average minimum value was obtained 27.54 while gender obtained an average maximum value of 32.04 and an average minimum value of 23.79 so that a decision could be made that reject H0 and accept H1.
Conclusions. So it can be concluded that there is an interaction between service training and gender on the service skills. The form of interaction shown by the results of this calculation provides a clear reason that the diversity of student characteristics will have an impact on the difference in service training, in this case a service training should pay attention to aspects of physical ability in this case gender in the implementation of training, so between service training and gender will influence each other and interact positively in the training process, especially in achieving the results of service skills  which is good.
The Impact of Big Data Analytics on Stock Price Prediction in the Bangladesh Stock Market: A Machine Learning Approach
Authors:   Gannon University, PA, USA. BBA- Accounting & Information Systems (AIS), United International University, MBA- Accounting & Information Systems (AIS), University of Dhaka, Dhaka, Bangladesh., Islam Md Zahidul , Chowdhury  Md Maruful Hoque ,   Business Development Manager, UNICAP Securities Limited, Dhaka, Bangladesh. MBA-Northern University Bangladesh. BBS-Accounting, Government College of Commerce, Chattogram. Under National University, Bangladesh., Sarker Mohammad Momen ,   Executive Commercial, Bengal Group of Industries, Dhaka, Bangladesh. MBA. BSS-Accounting, University of Chittagong, Bangladesh.
Published: October 2023

The stock market is a volatile and complex environment impacted by various unpredictable factors, making accurate stock price prediction challenging. This research paper explored the potential and capability of big data analytics and machine learning techniques in terms of enhancing stock price prediction accuracy in the setting of the Bangladesh stock market. The methodology adopted in the study entailed a data gathering process, which comprised collecting financial data from the Bangladesh stock market, such as news articles, financial statements, macroeconomic indicators, and historical stock prices. Based on a literature review, various fundamental and technical indicators are chosen as predictive features. The research paper employed a combined methodology that consolidates technical calculations and sentimental analysis to predict and forecast stock market patterns. By adopting machine learning and sentiment analysis techniques, this technique provides future predictions for the stock market while considering the impact of political events, economic factors, and dynamics in social media. The consolidation of big data analytics enables real-time predictions of stock market movements. The sentiment analysis algorithm facilitates prompt and extensive evaluations of tweets and news articles. As a result, the integration of technical and sentiment analyses greatly enhances the accuracy of stock market predictions.
Anti-Growth, Antioxidant, and Hepatoprotective Properties of Spirulina Platensis Extract
Authors: Ziyanok Sedef
Published: October 2023

Spirulina platensis (S. platensis), a filamentous cyanobacterium often referred to as a blue-green alga, is recognized for its antioxidant, immunomodulatory, and anti-inflammatory properties. This study aimed to examine the growth-suppressing effects of S. platensis ethanolic extract on PANC-1 and MIA PaCa-2 human pancreatic cancer cells. Additionally, the in vivo hepatoprotective and antioxidant properties of S. platensis were explored. The ethanolic extract of S. platensis was lyophilized and dissolved in DMSO. Subsequently, PANC-1 and MIA PaCa-2 cell lines were exposed to concentrations ranging from 0.1-1000 µg/ml. Cell viability was assessed using sulforhodamine B viability assay. For in vivo evaluation of hepatoprotective and antioxidant properties, S. platensis was administered by gavage at a dose of 50 mg/kg/day over a four-week period. The activities of superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), alanine aminotransferase (ALT), and aspartate aminotransferase (AST) were measured in the heart and liver of rats. The control group that received S. platensis showed a significant elevation in the activity of SOD and GSH-Px enzymes in the heart and liver tissues. There was a significant reduction in the ALT and AST enzyme levels. The extract notably hindered the growth of both the examined cell lines. Future research can focus on studying the effects of S. platensis extracts in conjunction with various chemotherapeutic agents or its effect on different cancer cell lines to better understand its anti-growth attributes.
Investing in People: Anticipating the Future of Research Software
Authors: Hartley Kim , Barker Michelle
Published: October 2023

October 2023 Authors: Kim Hartley and Michelle Barker We are proud to report that the second International Research Software Funders Workshop, co-hosted by the Digital Research Alliance of Canada (the Alliance) and the Research Software Alliance (ReSA) from 18-20 September was a great success.
Integrating Innovative Pedagogy Based on the Multiple Intelligences Theory (MIT) and Study Skills for Sustainable Development
Authors: Chetry Krishna Kumari , Prakash Dr Sumin , Sharma Monika
Published: October 2023

Introducing new teaching strategies and methods into the classroom is known as Innovative Pedagogy. This proactive approach aims to improve academic outcomes and promote equitable learning by addressing real problems. Innovative Pedagogy involves studying the effects of innovative teaching practices on the learning processes. This new teaching paradigm is based on theories that can be practically applied in the classroom. Under this paradigm, students play an active role in constructing, discovering, adjusting, and extending their knowledge. The 2030 Agenda for Sustainable Development underscores the need to incorporate the principles of education for sustainable development (ESD) into all levels of education. ESD is an integral part of quality education, and all educational institutions should foster the development of sustainability competencies. NEP 2020 strongly believes that education should be child-centric, with the holistic development of each learner as a primary objective. The MI theory-based pedagogical strategy and approach to teaching also emphasize the need for modern education systems and pedagogical processes to incorporate varied teaching methods that promote holistic and sustainable development in both scholastic and non-scholastic ways. This descriptive study based on secondary data sources justifies the need to develop 21st-century skills in learners and teachers by adopting various MI-based teaching and learning strategies and approaches.
Application of The Speed-Up Robust Features Method To Identify Signature Image Patterns On Single Board Computer
Authors: Nursalim  , Octiva Cut Susan , Sri Wahyuningsih Suluh , Lukman Hakim Muhammad , Hasti Novrini
Published: October 2023

Through the development of a signature pattern recognition program on SBC Beagle-bone Black, this research seeks to determine how to differentiate between real and false signatures. Three techniques of gathering data were employed in this study: interviews, observations, and a review of the literature. The quick application development method is the approach that is applied. The rapid, efficient, and brief development cycle (RAD) is emphasized. This study uses a use-case diagram to illustrate the application's logic and data flow. In this study, OpenCV is used as a digital image processing library along with the C++ programming language and QT creator as an integrated development environment (IDE). This application was subjected to both accuracy and functional testing. The following conclusions are drawn from the findings of the investigation and testing that was done: Using the fast library approach for approximate nearest neighbors (FLANN) and the speeded-up robust features (SURF) feature extraction method, the signature pattern recognition program on the Beagle-bone black SBC can differentiate between real and fraudulent signatures. Through the processes of generating image scale space, feature localization, and feature description, the SURF approach extracts feature from signature images. This signature pattern recognition application is one of the digital image processing apps that can be run on the Beagle-bone Black single board computer. This indicates that the specifications of the SBC Beagle-bone Black for digital image processing are good.
Linguística e ensino da língua materna
Authors: Redes Luí­s Filipe , Fonseca Joaquim
Published: October 2023

As minhas conceções no domínio que agora nos ocupa – Linguística e ensino da Língua Materna – mantêm-se, no essencial, fiéis ao que, já há alguns  anos, propunha em colaboração com Fernanda Irene Fonseca, em Pragmática Linguística e Ensino do Português (Coimbra, Almedina, 1977).

Dessas conceções, reteria aqui duas, que me parecem centrais: em primeiro lugar, o sentido que atribuo às relações linguística – ensino da língua materna; em segundo lugar, a definição da aula de língua materna. Algumas palavras breves sobre cada um destes pontos.
Histórias em 77 Palavras
Authors: Fonseca Santos Margarida
Published: October 2023

O blogue das 77 Palavras nasceu da necessidade de motivar os alunos para a escrita, envolvendo-os na construção de textos e levando-os até ao verdadeiro trabalho literário, ou seja, à revisão e apuramento da escrita. Com este propósito, são lançados desafios de escrita que vão melhorando, a cada desafio, a escrita dos alunos. Esses desafios partem de constrangimentos, como letras ou palavras obrigatórias, por exemplo, ou são mais livres, usando frases ou imagens como motores de escrita. Outro efeito deste trabalho constata-se quando, à medida que progridem na escrita, desenvolvem gosto pela leitura, centrando-se no «como se conta uma história», apreciando a escrita em si.
Em Destaque
Authors: Reis Carlos
Published: October 2023

A abordagem que aqui levarei a cabo deve ser entendida como tentativa de estabelecimento de uma correlação em que reconheço um certo potencial operatório: a correlação entre os estudos narrativos e o ensino do Português. Uma tal interação implica a adoção de uma atitude interdisciplinar que é favorecida pela natureza do ensino do Português, tal como entre nós ele é praticado, em especial nos anos de escolaridade mais avançados, designadamente os do Ensino Secundário. Nesse cenário socioeducativo, a interdisciplinaridade está matricialmente inscrita na didática do Português, ainda que com dificuldades e, às vezes, melindres que neste momento não aprofundo; refiro-me ao facto de o estudo da língua se conjugar com a análise de textos literários e de, por vezes e em termos não isentos de equívocos, estes serem utilizados como referência para o ensino e a aprendizagem do idioma.
O ensino bilingue na Guiné-Bissau
Authors: Scantamburlo Luigi , Feytor Pinto Paulo
Published: October 2023

Neste texto apresentam-se as experiências de ensino bilingue na GuinéBissau, entre a independência do país, em 1973, e a atualidade, com foco no Projeto de Apoio ao Ensino Bilingue nos Bijagós (PAEBB).
Criação de leitores, criação de mundos
Authors: Oliveira Carmo
Published: October 2023

Se os professores de língua materna conseguissem enriquecer a ideia, digamos, canónica de literatura, rapidamente perceberiam que os jovens realizam leituras que escapam àquilo que a tradição e inúmeros críticos literários crismaram como os clássicos.
Devemos celebrar o esforço dos alunos e torná-lo visível
Authors: Aido João Pedro
Published: October 2023

José Pinto Lopes tem um doutoramento em psicologia e é professor na Universidade de Trás-os-Montes e Alto Douro (UTAD), onde é responsável pela formação inicial, contínua e pósgraduada de professores e de psicólogos.Os seus interesses em investigação incluem aprendizagem cooperativa, avaliação formativa, comunidades de aprendizagem profissional, importância do feedback professor-aluno / aluno-professor no desempenho escolar, dificuldades de aprendizagem, estudo colaborativo da lição, pensamento crítico e gestão pedagógica da sala de aula, entre outros.Helena Santo Silva, que é também professora na mesma universidade, tem um doutoramento em Educação, Ensino da Biologia e da Geologia, e os seus interesses em investigação incluem supervisão pedagógica, aprendizagem cooperativa, comunidades de aprendizagem e avaliação formativa, entre muitos outros.O interesse comum por aprendizagem cooperativa, comunidades de aprendizagem e trabalho colaborativo, por exemplo, terá sido provavelmente decisivo para construírem em conjunto um trabalho de investigação notável nessas áreas que são reconhecidamente importantes, mas para as quais não tem havido investigação e sobretudo investigação-ação, conceito que parece mostrar de forma mais eficaz a atividade partilhada que têm desenvolvido e que se traduz na publicação conjunta de inúmeros livros e artigos em revistas com arbitragem científica, bem como capítulos de livros, participação em congressos e conferências, e muitas comunicações, ao longo dos anos.
Expressão oral: entre a avaliação holística e a avaliação analítica
Authors: Marques Carla
Published: October 2023

O artigo centra-se numa reflexão sobre os processos de avaliação do domínio da expressão oral na sala de aula. Partindo da hipótese de que no contexto do ensino-aprendizagem oral existem práticas comuns, adotadas por muitos professores e espelhadas nos materiais didáticos, defende-se que a abordagem desta competência se processa sobretudo de forma holística. Com base nos dados da observação empírica e na análise das grelhas de avaliação da expressão oral propostas pelos diferentes manuais escolares, pode-se deduzir que a escola tende a tratar as apresentações orais em todos os seus domínios em cada intervenção, desde o verbal ao cinésico e o paralinguística, sem se dedicar a conteúdos específicos. É ainda efectuada uma análise das Aprendizagens Essenciais de forma a identificar quer os conteúdos/conhecimentos ministrados em cada ano/ciclo lectivo, quer os planos orais contemplados e a sua organização ao longo do percurso escolar. Argumenta-se que esta conceção do ensino oral atual tem consequências para as práticas de avaliação que se orientam, igualmente, para uma observação holística que considera a globalidade dos parâmetros que envolvem uma apresentação oral.
Saber ler... Como extrair sentido de um texto?
Authors: Chagas Maria Manuela
Published: October 2023

São diversas as estratégias de leitura disponíveis para, após acesso a um texto, dele extrairmos a informação considerada essencial. A bibliografia acerca do tema (Azevedo, 2011; Benavente et al., 1996; Candeias, 2010; Delgado-Martins et al., 2000; Figueiredo, 2006; Tedesco, 2000) é unânime em afirmar que, atualmente, podemos falar de uma cada vez mais crescente comunidade escolarizada, alfabetizada2, mas iliterata3, isto é, incompetente, ou com parcas competências para compreender o que leu.Há cerca de três décadas, em 1992, a OCDE4 apresentou evidências do que parecia ser transversal às sociedades industrializadas: inúmeros adultos, devidamente escolarizados, alguns dos quais com uma extensa escolaridade obrigatória cumprida, eram incapazes de compreender o sentido de um texto lido, na sua língua materna, e cujo significado era reclamado, portanto, tido como importante para o desempenho da sua atividade profissional. A forma de comunicação escrita, que se pensava estar adquirida com o acesso generalizado à escolarização, revelou-se ainda ser um modo de expressão ao qual importa dedicar tempo e repensar estratégias para melhor aprimorar a técnica de compreensão/extração de sentido de um texto lido/ouvido.
Resumir textos narrativos e textos expositivos: do ensino às perceções dos alunos
Authors: Sousa Otí­lia Costa , Letras Joana , Dias Alfredo
Published: October 2023

A leitura e a escrita são duas competências básicas com impacto nas aprendizagens em todo o currículo. Compreender o que se lê e ser capaz de reorganizar a informação, retendo o essencial é uma competência que se torna cada vez mais importante à medida que se avança na escolaridade. O estudo é uma intervenção com metodologia de investigação-ação em três passos: pré-teste, intervenção, pós-teste e ainda auscultação dos alunos em dois grupos focais. Foi realizado em duas turmas do 6.º ano de escolaridade, numa escola TEIP, durante seis semanas. Teve como objetivos: (i) avaliar a competência de resumir dos sujeitos; (ii) desenvolver sequências didáticas para ensino do resumo em textos narrativos e informativos; (iii) desenvolver competências de leitura e de escrita. Os resultados revelam que os alunos valorizaram as atividades, desenvolveram atitudes muito positivas, com um maior envolvimento no trabalho de sala de aula e melhoraram as competências de leitura e escrita, conforme aferido pela comparação dos pré e pós-testes e pelos dados recolhidos no grupo focal.
Literatura no contexto acadêmico e escolar: a partilha do sensível
Authors: Amarilha Marly
Published: October 2023

O artigo apresenta argumentos sobre aspectos relevantes para o ensino de literatura na escola: o domínio de repertório diversificado e a mediação que valoriza a oralidade do texto. Toma-se como pressuposto a natureza humanística, inventiva e comunicativa, pela palavra, do discurso literário. Indica autores brasileiros que podem compor uma coleção contemporânea de obras para seu ensino na escola fundamental no Brasil e em Portugal. Destaca a relevância da leitura oral para valorizar o lastro de oralidade que compõe a multimodalidade da criação literária. Conclui-se que para realizar trabalho significativo no ensino de literatura é preciso valorizar seu teor humanístico, visual e oral.
A formação leitora no texto de Clarice Lispector
Authors: Pontes Verônica Araújo , Da Silva Hilma Garcia
Published: October 2023

Este trabalho tem o objetivo de apresentar uma análise em torno do conto "Felicidade Clandestina", de Clarice Lispector (1998), enfocando a sua personagem principal e relacionando as suas ações, enquanto ávida leitora, com o prazer que a leitura literária pode provocar. Além disso, suscitamos uma discussão sobre a escola e a formação de leitores. Com esse propósito, procuramos esclarecer o leitor sobre o conceito de leitura, de leitor, de literatura infantil e o que se diz a respeito ao prazer de ler. Para isso, utilizamos como método um estudo comparativo, alicerçado nos aportes teóricos de Barthes (1973), Smith (1997), Araújo (1996), Coelho (2007), Braith (2013) e Zilberman (2012), entre outros.
Lugares virtuais
Authors: Aido João Pedro
Published: October 2023

Apreciação e comentário sobre sítios da Internet interessantes.
Editorial
Authors: Duarte Isabel Margarida , Cunha Teresa Vieira
Published: October 2023

Introdução a esta edição da revista:

Além das secções habituais da revista, este número da Palavras – revista em linha reúne um conjunto de artigos que partilham várias características, a mais saliente das quais é serem exemplos de Investigação jovem.
Em destaque...
Authors: Pinto Paulo Feytor
Published: October 2023

Em 5 de maio, foi celebrado pela primeira vez o Dia Mundial da Língua Portuguesa (DMLP), decretado pela UNESCO. O português tornou-se assim a sétima língua a ter esse status e a primeira a alcançá-lo sem ser um idioma oficial das Nações Unidas (ONU). Esta é uma conquista notável para a diplomacia da CPLP (comunidade dos países de língua portuguesa), cujo objetivo imediato é o prestígio e o reconhecimento internacional da língua portuguesa e o fortalecimento de sua presença nas instituições da ONU.
Highlighted
Authors: Alexandre Eulália
Published: October 2023

The role of the school as a mediator of these top goods that are the national language and culture is undeniable.Language, as an organized system that we use to establish communication between the various subjects who use the same code, according to Ferdinand de Saussure, “is, at the same time, a social product of the language faculty and a set of necessary conventions, adopted by the body to allow individuals to exercise this faculty”. Understood, therefore, as social institution, resulting from a set of conventions, established and accepted by all who belong to a linguistic collectivity, language exists as a collective body. Therefore, only with the development of sociolinguistics it was possible to more precisely characterize the relations between language and society.
Contribution of gestational weight gain to fetal birth weight among pregnant women in a public tertiary hospital, Benin City, Nigeria
Authors: Enaruna NO  , Peter OO
Published: October 2023

Background: The ideal gestational weight gain (GWG) to ensure a favorable neonatal birth weight remains arguable but the desired birth weight for optimal early life adaptation and subsequent seamless childhood navigation is no longer in doubt.Objective: We sought to document the role of GWG on birth weight and to examine the influence of some materno-fetal variables.Method: The case records of patients who initiated antenatal care in the first trimester and delivered in University of Benin Teaching Hospital, Benin City from January 2014 to December 2017 were retrospectively studied. Data on sociodemographic characteristics, clinical management and outcome were extracted and analyzed.Results: The frequency of early booking was 14.5%. Mean GWG was 7.7±5.8kg and the mean birth weight was 3.1±0.4kg. GWG did not significantly influence birth weight. Social class was significantly associated with birth weight (P<0.001). Weight gain less than 5kg with OR of 1.52 (CI=1.02 to 2.04; P=0.042) and lower social class with OR of 1.81 (CI=1.23 to 2.57; P=0.02) predicted birth weight lower than 2.5kg. Maternal age, parity and fetal sex did not significantly impact on birth weight.Conclusion: Overall GWG in our study was poor but this did not significantly influence birth weight. GWG in the third trimester impacts on fetal growth, and low birth weight can be predicted by GWG lower than 5kg. A focus on improved GWG in the prenatal period to optimize birth weight appears necessary. We recommend nutritional counselling and support especially in the second half of gestation.
后疫情时代中学历史教学中的生命教育
Authors: Yi Xue
Published: October 2023

在后疫情时代，对学生进行生命教育显得尤为重要。历史学科作为一门人文学科，尊重人的生命，关注与关怀人，进而培养学生的人文精神与人文情怀，具有实施生命教育的独特优势。因此，历史教师需要树立关爱生命的教育理念，构建教师主导、学生主体的生命教育课堂，挖掘有关生命教育的历史素材，选择适合生命教育的教学方法，培养学生健康乐观的生活态度，帮助其实现生命价值，构建和谐社会。
As the epidemic approaches, basic education faces new challenges and opportunities, and life education has come back into the limelight, attracting more and more attention. In the post-epidemic era, it is worth considering how teachers of various subjects can find common ground and breakthroughs between life education and subject education, so as to add new vitality and creativity to students' learning and teachers' teaching. History, as a humanities subject, respects human life by paying attention to and caring for people, and then cultivates students' humanistic spirit and humanistic feelings. It has the distinct advantage of including life skills education. As a result, history teachers must develop an educational philosophy of caring for life, design a teacher-led and student-centered life education classroom, gather historical materials and teaching methods appropriate for life education, cultivate a healthy and optimistic attitude toward life, and assist students in realizing the value of life in order to build a harmonious society.
Pendampingan Pengembangan Green Village Sebagai Upaya Mengurangi Dampak Global Warming
Authors: Lestari Ayu Widia , Makki Mustaqim , Halim Abdul , Atika Istiatul , Munawwarah Siti
Published: October 2023

Pengembangan adalah suatu proses mendesain secara logis, dan sistematis dalam rangka untuk menetapkan segala sesuatu yang akan dilaksanakan dengan memperhatiakn potensi dan kopetensi masyarakat. Pengembangan juga dapat diartikan untuk memperkuat dan mengembangkan potensi masyarakat guna sebagai penunjang dalam kehidupan. Salah satu pengembangan adalah pengembangan green village dengan cara penanaman pohon secara serentak sebagai upaya mengurangi dampak pemanasan global. Melihat kondisi dan potensi masyarakat yang ada di Dusun Cottok Desa Sopet yang 80% berprofesi sebgai petani dan kurangnya kesadaran masyarakat untuk menciptakan lingkungan sehart, ramah, dan asri merupakan alasan untuk diadakannya penghijauan di Desa tersebut. Selain bertujuan untuk mengurangi pemnasan global penanaman pohon ini juga mampu meningkatkan taraf perekoomian masyarakat dengan perolehan hasil panen dari pohon yang ditanam. Dari hasil observasi dan wawancara terhadap masyarakat setempat yakni kurangnya minat masyarakat guna menjaga lingkungan agar tetap hijau dan nyaman untuk ditempati sehingga terjadi kegersangan yang bisa menyebabkan pemanasan global. Melihatkondisimasyarakat yang potensinya mayoritas pertanian, Sehingga menemukan suatu Program yang akan dilaksanakan yakni Green Village yang meliputi penanaman pohon dengan tujuan mengurangi dampak pemansan global, dan , meningakatkan taraf perekonomian di Dusun Cottok Desa Sopet.Serta memandu dan memberikan pemahaman terkait dengan bidang pertanian, menjaga kesehatan, dan menciptakan kenyamanan lingkungan..
Maulid Nabi Muhammad SAW sebagai Madia Akulturasi Kebudayaan
Authors: Syarbini Imam , Jali M , Samsudi Wedi
Published: October 2023

perayaan Maulid di Probolinggo  yaitu memajang  berbagai buah di halaman masjid kemudian diperebutkan saat pembacaan shalawat Nabi, di sisi lain, mirip acara grebeg maulid di Yokyakarta.. Dalam   penelitian  ini,  penulis   menggunakan  pendekatan  penelitian studi  kasus  yang  mana  peneliti  mengadakan penelitian secara intensif, perinci dan  mendalam terhadap variabel  atau  gejala tertentu. Studi  kasus  digunakan untuk kasus  di masyarakat yang unik dan menarik. Dalam  penelitian ini peneliti  juga  ingin  mengetahui dan  mempelajari kasus• kasus  yang  terjadi  dan  telah  menjadi  fokus  penelitian ini. Dari  studi  kasus  ini akan dihasilkan suatu  gambaran hasil  penelitian yang  mendalam dan  lengkap  sehingga dalam  informasi  yang  disampaikan tampak hidup sebagaimana adanya  dan  pelaku mendapat tempat  untuk memainkan perannya.. Pendekatan studi  kasus  ini, penulis  gunakan, karena  perayaan Maulid  kali ini unik    menampilkan   keragaman   budaya,    seolah-olah   akulturasi    kebudayaan. Dikatakan  unik,   karena   tahun-tahun  sebelumnya  tidak   ada.  Keunikan   tersebut tercermin dari  cara  masyarakat  menghias berkat  dengan  berbagai  buah  dengan di bentuk  parsel,   memajang  berbagai   buah   di  halaman  masjid,   setelah   pembacaan shalawat masyarakat saling  berebut buah,  model  shalawatannya ala  habib  Syeikh dan   sekali-kali   ala  Wali  sanga,   musik   gamelan.  Syiamya  "Nada  dan   Dakwah" ceramah  diselingi  Shalawat.
Pemberdayaan Ibu-ibu Petani melalui Pemanfaatan Limbah Plastik Sebagai Bahan Dasar Pembuatan Tas
Authors: A.T Weni Indah Doktri , Purwatiningsih Rini , Soemarjono Eko
Published: October 2023

Limbah sedotan dan gelas plastik masih belum dilirik oleh ibu-ibu petani sebagai alternatif sumber penghasilan mereka. Berdasarkan survey lapangan didapatkan masih banyak sampah terutama sedotan dan gelas plastik yang berserakan di sungai maupun di jalan-jalan. Banyak dari istri-istri petani membuang begitu saja limbah sedotan dan gelas plastik. Mereka masih belum banyak mengetahui manfaat sedotan dan gelas plastik.

.  Kegiatan pengabdian ini menggunakan metode PRA (Participatory Rural Approach) dimana program pengabdian ini dirancang untuk kebutuhan warga setempat dan istri petani ikut berperan aktif dalam program ini. Kegiatan ini meliputi penyuluhan hidup bersih dan pengelolaan sampah kemudian pelatihan pembuatan tas berbahan dasar sedotan dan gelas plstik. Kegiatan pengabdian berjalan dengan lancar dan istri petani antusias mengikuti program pelatihan ini.
Jön Türkler ve II. Meşrutiyet Dönemine Genel Bir Bakış
Authors: ALKAN AYKAÇ Songül
Published: October 2023

Fransız Devrimi’nin mirası özgürlük, eşitlik, anayasacılık gibi fikirler, Batı-dışı toplumları da etkilemiş ve ulusçuluk hareketlerini hızlandırmıştır. Osmanlı imparatorluğunda ise bu tartışmalara dağılma sürecinde karşılaşılır. Bu süreçte Osmanlı’yı dağılmaktan kurtaracak çözüm bulma çabaları da ortaya çıkar. “Bu devlet nasıl kurtulur?” sorusunun cevabını arayan aktörlerden önemli bir kısmı II. Abdülhamit muhalefetinin omurgasını oluşturan Jön Türk hareketidir. Parlamenter sistem, eşitlik, hürriyet, özgürlük talep eden Jön Türkler, bu talepler çerçevesinde Sultan Abdülhamit’e yönelik şiddetli bir muhalefet geliştirirler. Jön Türk hareketi, yalnızca Osmanlı’nın son dönemi için değil, aynı zamanda Jön Türkler-İttihat ve Terakki ve Cumhuriyet Halk Fırkası arasında bulunan organik bağ itibariyle de dikkate değerdir.

Bu çalışmada Osmanlı’nın son dönemlerinde ortaya çıkan ve Cumhuriyet Türkiye’sine giden yolun köşe taşlarını döşeyen bir hareketin, Jön Türk hareketinin ortaya çıkışı, amaçları ve hareketin en önemli icraatlarından biri olarak II. Meşrutiyet’in ilanıyla oluşan siyasal ve toplumsal gelişmelerin, sonuçlarıyla birlikte incelenmesi amaçlanmaktadır.
Significant histological changes are not rare in indeterminate‐phase chronic hepatitis B patients with hepatitis B e antigen‐negative and normal alanine aminotransferase levels
Authors: Huang Deliang , Zhou Guangde , Peng Jinghan , Cai Qinxian , Li Guojun , Yu Hong , Zhu Zhibing , Chen Yuanyuan , Lai Huiyi , Jiang Jinyan , Yu Hong , Chen Jun
Published: October 2023

Background & Objectives

The degree of liver injury in indeterminate chronic hepatitis B (CHB) infection patients with Hepatitis B e antigen(HBeAg)‐negative and persistently normal alanine aminotransferase (PNALT) levels is yet unclear. Therefore, we aimed to assess liver histological changes in such patients by liver biopsy and explore possible predictors.

Methods

Overall, 711 HBeAg‐negative CHB patients with PNALT levels who underwent liver biopsy from January 2017 to June 2022 were included in this retrospective study. The relationships between histological changes and predictors were assessed by smooth curve fitting and multivariate logistic regression analysis models. Data were also analyzed using American Association for the Study of Liver Disease (AASLD) modified alanine aminotransferase (ALT) criteria.

Results

The proportion of significant histological changes in the indeterminate phase was higher than that in the inactive phase (53.97% vs. 41.33%). The adjusted odds ratios (aORs) of significant necroinflammation and histological changes for the indeterminate phase were 2.05 and 1.43, respectively, when compared with the inactive phase by multivariate logistic regression analyses. Significant histological changes in the‐phase were positively associated with age, ALT, Aspartate aminotransferase (AST), Hepatitis B surface antigen (HBsAg), and Hepatitis B virus (HBV) DNA levels but negatively correlated with platelet (PLT) levels. HBV DNA ≥5 log10 U/L and PLT <200 × 109/L were independent predictive factors for assessing histological changes in indeterminate‐phase patients. Similar analysis findings were obtained using the two sets of modified ALT criteria.

Conclusions

Significant histological changes are not rare in indeterminate‐phase CHB patients and are higher than in the inactive phase, regardless of the ALT criteria. Histological investigation is strongly suggested for intermediate stage patients with HBV DNA >5 log10 U/L or PLT <200 × 109/L and antiviral therapy should be considered for such patients.
Ecology and Biodiversity of Coral Reef Polychaetes of Guam and Saipan, Mariana Islands.
Authors: Bailey‐Brock Julie H.
Published: October 2023

Polychaetes collected from coral reefs and other coastal habitats on Guam and Saipan, and information from published studies bring the known number of species from these two islands to 101 and 15, respectively. Sediment and rock dwelling species collected, and those previously recorded, belong to 25 families. Polychaete assemblages are compared on the basis of species richness, genera in common, and trophic categories, with other West Pacific, Hawaiian and East Indian Ocean locations. Polychaetes from Guam are similar to those on reef flats of Hawaii, Enewetak, and Indonesia in faunal composition and density. Despite the limitations in comparable collecting effort and quantitative analyses for some of the areas, these coral reefs have similar complements of families and genera present, and proportions of four trophic categories.
Periphyton Architecture and Susceptibility to Grazing by Periwinkles (Littorina littorea, Gastropoda)
Authors: Sommer Ulrich
Published: October 2023

Periphyton was grown on transparent plastic substrata in the Kiel Fjord and used for short‐term laboratory experiments to study the feeding selectivity of the periwinkle Littorina littorea in response to the vertical structure of the periphyton. The susceptibility of algae to periwinkle grazing was assessed by comparing the species‐specific biomass within the grazing tracks of the snails to the biomass outside the tracks. After 3 weeks of incubation, the periphyton consisted of a scattered monolayer of algal cells without vertical structure. No apparent grazing could be found. After 6 weeks of incubation, periphyton consisted of a tightly attached undergrowth (mainly Cocconeis scutellum, Bacillariophyceae, and Myrionema sp., Phaeophyceae) and canopy of filamentous (Melosira moniliformis, Bacillariophyceae) and stalked forms (Achnanthes longipes, Bacillariophyceae). The unicellular diatoms Fragilaria tabulata and Stauroneis constricta grew partly on the primary substratum and partly as epiphytes on the canopy species. The canopy species and the epiphytes were decimated inside the grazing tracks, while the tightly attached undergrowth species appeared ungrazed.
Basin‐Wide Considerations for Water Quality Management: Importance of Phosphorus Retention by Reservoirs
Authors: Kennedy Robert H.
Published: October 2023

The relationship between phosphorus retention (RP) and water residence time (RT) was assessed for selected U.S. Army Corps of Engineers reservoirs and found to be influenced by areal phosphorus loading rate (PL). For reservoirs with high PL (>15 gm/m2/yr), RP increased markedly with modest increases in RT. Reservoirs with lower values of PL exhibited less dramatic responses in RP to changes in RT. The water quality management implications of this are great since reservoirs for which marked changes in RP can occur with modest changes in RT are potential management loci within a drainage basin.
Measurement of Protein C Inhibitor in Seminal Plasma Is Useful for Detecting Agenesis of Seminal Vesicles or the Vas Deferens
Authors: KISE HIDEAKI , NISHIOKA JUNJI , SATOH KENJI , OKUNO TOSHIYUKI , KAWAMURA JUICHI , SUZUKI KOJI
Published: October 2023

ABSTRACT: Protein C inhibitor (PCI), a plasma serine protease inhibitor of activated protein C, is present at high concentrations in the seminal plasma of normal subjects and is decreased in some infertile patients. We measured the concentrations of PCI, prostate‐specific antigen, and fructose in the seminal plasma of infertile patients (n = 125) and of normal subjects (n = 13). We also measured time‐dependent changes in the concentrations of PCI and fructose in seminal plasma after ejaculation. A weak correlation was found between the levels of PCI and fructose (r =0.268, P = 0.016). The PCI level in seminal plasma of patients with seminal vesicle and/or vasal agenesis was significantly lower (P < .01) than in normal subjects. The level of fructose in seminal plasma decreased in vitro in a time‐dependent manner after ejaculation, whereas the concentration of PCI was stable at 48 hours after ejaculation. These data suggest that PCI in seminal plasma, as well as fructose, may become one of the markers for agenesis of seminal vesicles and/or the vas deferens.
Dipeptidylpeptidase IV Activities Are Elevated in Prostate Cancers and Adjacent Benign Hyperplastic Glands
Authors: WILSON MICHAEL J. , RUHLAND AMY R. , QUAST BARRY J. , REDDY PRATAP K. , EWING STEPHEN L. , SINHA AKHOURI A.
Published: October 2023

ABSTRACT: Dipeptidylpeptidase IV (DPP IV) is a serine exopeptidase that has been implicated in cell‐extracellular matrix interactions and bioactive peptide/cytokine/growth factor metabolism. The objective of this study was to determine if DPP IV activities were changed with development of cancer in the prostate. DPP IV activity was measured in human prostate cancer and benign prostatic hyperplasia (BPH) tissues by biochemical assays with glycylprolyl‐p ‐nitroanalide as substrate in tissue extracts (BPH, n =8: cancer, n = 7; 2 with Gleason score 5 and 5 with Gleason score 7) and quantitative morphometry of histochemical activities with glycylproline‐4‐methoxy‐β‐naphthylamide as substrate (BPH, n = 9: cancer, n = 13, 1 with Gleason score 4, 10 with Gleason score 6, 2 with Gleason score 8) in frozen‐tissue sections. Data were analyzed by analysis of variance. The peptidase activity was detected in epithelial but not stromal cells of BPH and cancer tissues, and it was present as a single band of activity of approximately 160 kDa in electrophoretically separated activity blots of the extracts. DPP IV activity was increased approximately twofold in cancer versus BPH tissues as determined by biochemical and quantitative histochemical methods. In addition, DPP IV activity was increased to a similar extent in BPH glands associated with the cancers. These data indicate that DPP IV activity is increased not only in primary prostatic cancers but also in associated BPH glands, suggesting that there may be some local factors produced by cancer cells that influence adjacent BPH epithelial cells to positively affect the immediate growth environment of the cancer.
Measurement of Intracellular Calcium Concentration and Plasma Membrane Potential in Human Spermatozoa Using Flow Cytometry
Authors: BREWIS IAN A. , MORTON IAN E. , MOHAMMAD SOPHIA N. , BROWES CLARE E. , MOORE HARRY D.M.
Published: October 2023

ABSTRACT: We report 2 novel approaches using flow cytometry to measure intracellular calcium concentration and plasma membrane potential in human spermatozoa. Both approaches have the potential to measure different responses in subpopulations of cells, which is particularly useful when studying heterogeneous populations such as human spermatozoa. Intracellular calcium concentration ([Ca2+],) was measured using the probe indo‐1/AM. This allowed measurements to be made that were independent of variation in cell size and dye loading. It also enabled dead cells to be directly identified and excluded from the analyses without the need for counter‐staining. Mean basal [Ca2+], was determined as 50 nM (25–75 μM range) and, in response to the agonist progesterone (20 μM), this increased transiently to 195 nM (125–285 nM range) before declining to approximately half the maximal level within 2 minutes (values in parentheses correspond to the range of values typically found within a sperm population from 1 sample). These results are comparable with previously published data on whole sperm populations. Sperm membrane potential (VM) was assayed using the probe DiOC6(3). In carefully controlled experiments, a marked depolarization of the plasma membrane potential of capacitated spermatozoa was observed in response to progesterone (20 μM). Following in vitro capacitation, the sperm plasma membrane potential became hyperpolarized compared with the noncapacitated state. Therefore, this technique may be used to assay for sperm capacitation in vitro.
The Antigonadotropic Action of Testosterone but not 7α‐Methyl‐19‐Nortestosterone Is Attenuated Through the 5α‐Reductase Pathway in the Castrated Male Rat Pituitary Gland
Authors: BANDIVDEKAR ATMARAM H. , KARP RUSSELL , SUNDARAM KALYAN , KUMAR NARENDER
Published: October 2023

ABSTRACT: The enzyme 5α‐reductase plays a significant role in the prostate to amplify the action of testosterone (T) by converting it to a more potent androgen, dihydrotestosterone (DHT). The role of 5α‐reductase in the testosterone feedback inhibition of gonadotropin secretion from the pituitary has not been elucidated. Therefore, we investigated the role of 5α‐reductase on T action in in vitro and in vivo models. Castration has been reported to increase the 5α‐reductase activity in pituitary glands. Hence, the effect of castration duration on the conversion of T to DHT by pituitary homoge‐nates and the responsiveness of pituitary monolayer cell cultures to gonadotropin‐releasing hormone (GnRH) challenge exposure were investigated. Incubation of [3H]‐T with pituitary homogenatesshowed that the conversion of T to 5α‐reduced metabolites was two‐to threefold greater in pituitaries from rats who had been castrated for 14 days compared with those castrated for 1 day. In addition, the GnRH‐stimulated release of LH from monolayer cell cultures of pituitaries from rats castrated for 1 day was twofold greater, whereas that from rats castrated for 2 weeks was six‐ to sevenfold greater compared with basal luteinizing hormone (LH) release. Hence we used rats castrated for 2 weeks to elucidate the role of 5α‐reductase in T feedback inhibition. The inhibitory effects of the androgens T, 19‐nortestosterone (19‐NT), and 7α‐methyl‐19‐nortestosterone (MENT) at 3 different concentrations (10−9, 10−7, and 10‐5 mol/L) on GnRH‐stimulated LH release from monolayer cell cultures of pituitaries from rats castrated for 2 weeks were examined. All 3 androgens showed dose‐dependent inhibition of LH release. MENT showed the greatest inhibition, followed by 19‐NT and T. In the presence of finasteride (a 5α‐reductase inhibitor), the inhibition of LH released by T and 19‐NT were significantly greater. The inhibitory effect of MENT, which does not undergo 5α‐reduction, was not altered by finasteride. In an in vivo study, rats castrated for 2 weeks received T with or without finasteride. There was a significantly greater suppression of serum LH in rats receiving T plus finasteride compared with those receiving T alone. These results suggested that 5α‐reductase in the pituitary is not obligatory for the inhibitory action of T on gonadotropin secretion in the castrated rat. The action of MENT, a nonreducible androgen, on the pituitary is not affected by 5α‐reductase.
Identification and Regulation of Receptor Tyrosine Kinases Rse and Mer and Their Ligand Gas6 in Testicular Somatic Cells
Authors: CHAN MICHAEL C. W. , MATHER JENNIE P. , MCCRAY GLYNIS , LEE WILL M.
Published: October 2023

ABSTRACT: Receptor tyrosine kinases act to convey extracellular signals to intracellular signaling pathways and ultimately control cell proliferation and differentiation. Rse, Axl, and Mer belong to a newly identified family of cell adhesion molecule—related receptor tyrosine kinase. They bind the vitamin K‐dependent protein growth arrest—specific gene 6 (Gas6), which is also structurally related to the anticoagulation factor Protein S. The aim of this study is to investigate the possible role of Rse/Axl/Mer tyrosine kinase receptors and their ligand in regulating testicular functions. Gene expression of Rse, Axl, Mer, and Gas6 in the testis was studied by reverse transcriptase‐polymerase chain reaction (RT‐PCR) and Northern blot analysis. The results indicated that receptors Rse and Mer and the ligand Gas6 were expressed in the rat endothelial cell line (TR1), mouse Leydig cell line (TM3), rat peritubular myoid cell line (TRM), mouse Sertoli cell line (TM4), and primary rat Sertoli cells. Axl was not expressed in the testicular somatic cells by RT‐PCR or Northern blot analysis. The highest level of expression of Gas6 messenger RNA (mRNA) was observed in the Sertoli cells, and its expression was responsive to the addition of forskolin in vitro. The effects of serum, insulin, and transferrin on Gas6 expression by TM4 cells were examined. It was shown that they all exhibited an up‐regulating effect on Gas6 expression. The forskolin‐stimulated Gas6 expression was accompanied by an increase in tyrosine phosphorylation of the Rse receptor in vitro, suggesting that Gas6 may exhibit an autocrine effect in the Sertoli cells through multiple tyrosine kinase receptors. Our studies so far have demonstrated that tyrosine kinase receptors Rse and Mer and their ligand Gas6 are widely expressed in the testicular somatic cell lines and may play a marked role in promoting testicular cell survival.
Initial Predominance of the Oxidative Activity of Type I 11β‐Hydroxysteroid Dehydrogenase in Primary Rat Leydig Cells and Transfected Cell Lines
Authors: GE REN‐SHAN , HARDY MATTHEW P.
Published: October 2023

ABSTRACT: Glucocorticoids suppress testosterone production in Leydig cells. The level of glucocorticoid action is set within the Leydig cell by the number of glucocorticoid receptors and by the activity of 11 β‐hydroxysteroid dehydrogenase (11 βSHSD). This enzyme acts either as an oxidase inactivating glucocorticoid or as a reductase amplifying its action. It is currently unknown whether extracellular conditions might cause 11 βSHSD oxidative and reductive activities in Leydig cells to change inversely or independently. The aim of the present study was to determine whether extracellular conditions set in vitro by various culture time and media components, such as glucose and pyruvate, affect the relative rates of 11 βSHSD oxidation and reduction. Primary rat Leydig cells and cell lines (COS1 and CHOP cells) transfected with 11 βSHSD‐I complementary DNA (cDNA), were incubated with 25 nmol/L (physiologic range) or 521 nmol/L (stress range) concentrations of radiolabeled substrates, corticosterone or 11‐hydrocorticosterone, for 0 to 24 hours. Oxidative activity predominated over reductive activity under initial conditions when product formation increased linearly with time. For example, in Dulbecco's modified Eagle medium/F12 medium (containing 5.5 mmol/L glucose), the peak ratio of oxidation to reduction (with 1 denoting equivalence of oxidative and reductive activities) was 5.5 in rat Leydig cells, 19.7 in COS1 cells, and 20.8 in CHOP cells. Glucose stimulated reductive activity but did not change the predominant direction of 11 βSHSD catalysis at earlier times. In COS1 cells transfected with 11 βSHSD‐I cDNA, oxidative activity rapidly increased during the first 2 hours of the incubation, then gradually decreased while reductive activity increased steadily. The relative ratio of oxidation to reduction rapidly declined to less than 0.5 at 6 hours, and thus the favored direction of catalysis changed from oxidation to reduction. However, in transfected CHOP cells, 11βSHSD oxidative activity rapidly increased during the first 2 hours and continued to increase for 24 hours. The ratio of oxidative to reductive activity rapidly declined but kept above 1 in CHOP cells for 24 hours, and the favored direction of catalysis remained predominantly oxidative. These results revealed that 11 βHSD‐I is a predominant oxidase initially in Leydig cells and 2 cell lines, and that the oxidative activity is gradually lost over time. The data suggest that type I 11βSHSD is a predominant oxidase in Leydig cells in vivo.