bluuebunny/crossref_metadata_2025 huggingface dataset:
ANALISIS PREDIKSI JUMLAH PENDUDUK DI KOTA PASURUAN MENGGUNAKAN METODE ARIMA
Authors: Mardiyah Ilmiatul , Dianita Utami Wika , Rini Novitasari Dian Candra , Hafiyusholeh Moh. , Sulistiyawati Dewi
Published: September 2021

Laju pertumbuhan penduduk di Kota Pasuruan pada tahun 2019 sebesar 0.68% dengan jumlah penduduk 200.422 jiwa. Tingginya pertumbuhan penduduk dapat mempengaruhi kepadatan penduduk. Penelitian ini bertujuan untuk memprediksi pertumbuhan penduduk Kota Pasuruan menggunakan metode ARIMA (Autoregressive Integrated Moving Average). Metode ARIMA adalah cara prediksi data deret waktu yang memiliki tiga model, yaitu AR (Autoregressive), MA (Moving Average), ARMA (Autoregressive Moving Average). Metode ini memiliki parameter (p,d,q) dapat diketahuidari plot ACF dan PACF untuk memastikan model yang akan digunakan untuk prediksi. Dalam penelitian ini data yang digunakan merupakan data penduduk Kota Pasuruan tahun 1983 sampai tahun 2019 sejumlah 37 data. Dari data tersebut didapatkan ARIMA model (1,1,1) dengan jumlah penduduk Kota Pasuruan pada tahun 2020 adalah 203.221 jiwa, didapatkan nilai MSE 10542507.06 dan MAPE 1.52%.
ANALISIS KESTABILAN MODEL SEIR UNTUK PENYEBARAN COVID-19 DENGAN PARAMETER VAKSINASI
Authors: Jannah Miftahul , Ahsar Karim Muhammad , Yulida Yuni
Published: September 2021

Covid-19 adalah penyakit menular yang disebabkan oleh coronavirus disease jenis baru, yaitu SARS-CoV-2. Oleh WHO, penyebaran Covid-19 telah ditetapkan sebagai pandemi global sejak 11 Maret 2020. Pada penelitian ini, penyebaran Covid-19 dimodelkan dengan menggunakan model matematika epidemik, yaitu model SEIR (Susceptible, Exposed, Infected, and Recovered) dengan memperhatikan faktor vaksinasi sebagai parameter. Selanjutnya, ditentukan titik ekuilibrium dan bilangan reproduksi dasar, serta diberikan analisis kestabilan pada model.
PERENCANAAN LOKASI STASIUN PENGISIAN BAHAN BAKAR GAS (SPBG) UNTUK WILAYAH KOTA PADANG
Authors: Fitri Meldia , Adelino Muhammad Ilham , Nurhasanah Wulan
Published: September 2021

Lokasi Stasiun Pengisian Bahan Bakar Gas (SPBG) strategis dengan jumlah optimal menjadi hal yang perlu dipertimbangkan di kota Padang. Kota Padang saat ini masih belum memiliki lokasi SPBG. Tujuan dari penelitian ini adalah untuk merencanakan jumlah dan lokasi kandidat SPBG yang optimal di kota Padang. Metode yang digunakan adalah 0-1 Integer Linear Programming dengan menggunakan dua skenario. Skenario pertama adalah lokasi SPBU saat ini dijadikan sebagai kandidat SPBG. Skenario kedua menambahkan alternatif lokasi SPBG baru. Hasil yang didapatkan adalah jumlah kandidat SPBG optimal sebanyak 11 kandidat. Jumlah tersebut konsisten pada skenario pertama dan kedua. Lokasi kandidat SPBG yang terpilih pada kedua skenario tersebut adalah Simpang Kalumpang, Balai Gadang, Batang Arau, Pitameh, Bandar Buat, dan KKSP Indarung. Lokasi kandidat SPBG yang dipilih pada skenario pertama, yaitu Sawahan, Kubu Marapalam, Pasar Ambacang, Mata Air, dan Bungus, digantikan dengan lokasi di Ranah, Ulak Karang 3, Kandidat 1, Pisang, dan Kandidat 9 pada skenario kedua
PENERAPAN METODE AUTOREGRESSIVE INTEGRATED MOVING AVERAGE (ARIMA) UNTUK PREDIKSI BILANGAN SUNSPOT
Authors: Yuliawanti Felia Dria , Novitasari Dian C. Rini , Widodo Nanang , Hamid Abdulloh , Utami Wika Dianita
Published: September 2021

Peristiwa magnetik pada matahari ditandai dengan salah satu tanda yaitu munculnya sunspot atau bintik matahari. Sunspot terletak di fotosfer matahari yang memiliki warna lebih gelap dari pancaran sekitarnya. Tujuan dari penelitian ini adalah untuk memprediksi bilangan sunspot dengan menggunakan metode ARIMA. Metode ARIMA dilakukan dengan melihat plot ACF dan PACF untuk mendapatkan model yang akan digunakan dalam prediksi. Penelitian ini menggunakan data bilangan sunspot yang dimulai dari bulan Januari tahun 1987 hingga bulan Desember 2019 sebanyak 396 data. Dari data tersebut didapatkan 4 model ARIMA yaitu ARIMA(3,1,2), ARIMA(3,1,1), ARIMA(2,1,2), ARIMA(2,1,1). Dari keempat model tersebut, model terbaik yang digunakan untuk prediksi yaitu ARIMA(2,1,2) dengan nilai AIC sebesar -884,87.
PETRI NET MODEL IN THE PROCESS OF SUBMISSION FOR CUSTOMER CREDIT OF BPR LAMBANG GANDA SERANG
Authors: Octavia Megawati , Fitriani Fitriani , Faisol Ahmad
Published: September 2021

The credit application process is one of a service that involves queues. This study aims to determine the design of the credit process application service system at the Lambang Ganda Serang Credit Bank using the Petri Net model. This study has 12 places, eight transitions, six operators, and 22 arcs of Petri Net model from credit application service system using Woped 3.2.0 version software
ANALISIS ASURANSI PENGANGGURAN DENGAN ASUMSI NON-ZERO MORTALITY
Authors: Widana I Nyoman , Winada Gautama I Putu
Published: September 2021

Indonesia dengan jumlah penduduk sekitar 267 juta jiwa memiliki angkatan kerja sangat besar. Tetapi jumlah lapangan kerja yang tersedia tidak mampu menyerap semua angkatan kerja ini. Selain itu angka pemutusan hubungan kerja juga relatif masih tinggi. Hal ini membuat pemerintah melontarkan wacana program asuransi pengangguran. Sejauh  ini telah dilakukan studi tentang hubungan besar premi dan benefit  dari asuransi pengangguran. Tetapi,  model yang digunakan  dalam perhitungan preminya, dibentuk berdasarkan  asumsi zero mortality. Tujuan dari penelitian ini  adalah menganalis asuransi pengangguran dengan asumsi non-zero mortality. Metode yang digunakan adalah  The Equivalence Principle. Hasil Perhitungan menunjukkan tarif premi untuk non-zero mortality  nilainya lebih kecil dari pada tarif premi untuk  zero mortality.
OPTIMASI JALUR EVAKUASI BAGI PEJALAN KAKI MENGGUNAKAN ALGORITMA FUZZY DIJKSTRA DI KECAMATAN TELUK SEGARA, BENGKULU
Authors: Mayasari Zulfia Memi , Afandi Nur
Published: September 2021

Provinsi Bengkulu terletak di pesisir barat Pulau Sumatera dan tepat berada di antara pertemuan dua lempeng dunia yang sangat aktif yaitu Lempeng Benua Eurasia dan Lempeng Samudra Indo-Australia.  Hal ini  menyebabkan Provinsi Bengkulu tergolong sebagai provinsi yang sangat rawan terhadap bencana gempa bumi dan tsunami.  Penelitian ini mengkaji persoalan optimasi pencarian rute evakuasi tsunami.  Tujuan penelitian ini adalah menentukan rute evakuasi dari tiap-tiap cluster yang telah dibentuk menuju tempat berkumpul yang telah ditentukan. Tiap-tiap cluster, titik berkumpul dan ruas jalan yang menghubungkannya dibentuk menjadi suatu graph jaringan jalan dimana cluster dan titik berkumpul diwakili oleh vertex dan ruas jalan diwakili oleh edge.  Graph  jaringan jalan ini diberi bobot dimana dalam penentuan bobotnya menggunakan logika fuzzy dengan mempertimbangkan beberapa parameter yaitu panjang jalan, lebar jalan, dan jumlah penduduk yang berpengaruh pada tingkat keramaian dan tingkat kemacetan.  Penentuan rute optimalnya dilakukan dengan menggunakan algoritma Dijkstra.  Berdasarkan hasil penelitian, diperoleh rute optimal dari tiap-tiap cluster menuju tempat berkumpul yang telah ditentukan
ANALISIS MODEL EPIDEMIK SVEIR DENGAN CONTINUOUS TIME MARKOV CHAIN (CTMC) PADA PENYAKIT RUBELLA
Authors: Eliska Nur , Sumarno Hadi , Sianturi Paian
Published: September 2021

Penyakit rubella yang dikenal dengan sebutan campak Jerman adalah penyakit menular yang disebabkan oleh virus rubella. Penelitian ini mempelajari model dinamika penyebaran penyakit rubella menggunakan model SVEIR yang merupakan modifikasi dari model yang dikembangkan oleh Beraud dan Saito, dengan pendekatan stokastik CTMC. Simulasi dilakukan untuk mengamati pengaruh perubahan: nilai awal, laju infeksi ( ), tingkat efektivitas vaksin ( ), dan laju vaksinasi ( ). Berdasarkan hasil simulasi diperoleh bahwa, perubahan nilai awal mempengaruhi peluang terjadinya wabah. Semakin tinggi laju sembuh dapat menurunkan peluang wabah. Sedangkan semakin tinggi tingkat efektivitas vaksin dan laju vaksinasi menyebabkan nilai  semakin rendah serta nilai peluang wabah yang cukup kecil; artinya peluang bebas penyakit semakin besar dan menghilangnya penyakit rubella dari sistem
Полипренолы при остром коронарном синдроме: результаты исследования Polyncor
Authors: Вышлов Евгений Викторович , Цой Екатерина Игоревна , Лебедева Елена Владимировна , Рябов Вячеслав Валерьевич
Published: September 2021

Проведено исследование по протоколу «Одноцентровое рандомизированное двойное слепое плацебо-контролируемое исследование эффекта полипрелонолов у больных острым коронарным синдромом «Polyncor» (№ NCT03122340 на ClinicalTrials.gov). 68 больных нестабильной стенокардией и острым инфарктом миокарда, на фоне стандартной терапии, включающей статины. Пациенты, согласно рекомендациям, были рандомизированы на 2 группы: больные 1 (основной) группы (n = 34) получали ропрен по 8 капель внутрь 3 раза в день (144 мг/день) в течение 3 недель, затем по 3 капли 3 раза в день (90 мг/день) в течение 5 недель; больные 2 (контрольной) группы (n = 34) получали плацебо (чистое растительное масло) с тем же режимом дозирования. На момент рандомизации по основным клинико-анамнестическим характеристикам группы между собой не различались. Через 2 мес терапии количество больных, которым пришлось уменьшить дозу или временно отменить аторвастатин по причине повышения АЛТ выше 3 верхних границ нормы в основной группе было меньше, чем в контрольной: 3 в сравнении с 9 (p < 0,05). Кроме этого, через 2 месяца терапии в основной группе уровни депрессии по шкале Шихана и тревоги по шкале CES-D оказались значительно меньше, чем в группе плацебо, а когнитивные функции по шкале MoCA при этом — лучше. Различий по уровням общего холестерина и холестерина ЛПНП и ЛПВП между группами не обнаружено.
Влияние адепрофена на фертильность крыс самок
Authors: Бугаева Л. И. , Денисова Татьяна Дмитриевна , Кузубова Е. А. , Мазанова Ю. А. , Мальцев М. В. , Озеров А. А. , Щербакова Н. М. , Саликова Л. Р.
Published: September 2021

Изучено влияние адепрофена (нового производного аденина с антидепрессивной активностью) на эстральный цикл и фертильность крыс самок. В эстральной цикличности, у крыс самок под влиянием адепрофена (2-недельное внутрижелудочное введение) в дозах 10 мг/кг (терапевтическая доза, ТД) и 150 мг/кг (15 ТД) не изменяется длительность фаз эструс и проэструс, но при этом дозозависимо удлиняется фаза метаэструс (на 33,3 и 50 %, p < 0,05), и укорачивается диэструс (на 15,1 %, p < 0,05). В процессах фертильности, у этих крыс самок, спаренных с интактными самцами отмечено отсутствие различий с контролем по индексу беременности и плодовитости, но дозозависимое снижение общей эмбриональной гибели. Полученные данные могут свидетельствовать о позитивном влиянии адепрофена на процессы фертильности крыс самок.
Влияние стимулятора эндогенного интерферона на фагоцитарную активность лейкоцитов периферической крови
Authors: Годовалов Анатолий Петрович , Eliáš Daniel , Боев Иосиф Александрович , Степанов Максим Сергеевич
Published: September 2021

Изучено влияния циклоферона на фагоцитарную активность лейкоцитов периферической крови здоровых доноров. Показано, что циклоферон стимулирует поглотительную активность лейкоцитов в среднем на 40 % (p ≤ 0,05), снижая численность не фагоцитирующих клеток. Кроме этого увеличивается количество клеток, захвативших большое число объектов в среднем в 2 раза (p ≤ 0,05). Преимущественное влияние препарат оказывает на моноциты, что, возможно связано с действием интерферона-γ.
Противовирусная активность ациклогермания при экспериментальной герпесвирусной инфекции
Authors: Алимбарова Людмила Михайловна , Амбросов И. В. , Матело С. К. , Баринский И. Ф.
Published: September 2021

Целью исследования явилась оценка противовирусной активности ациклогермания (комплексного соединения, состоящего из 2 атомов германия, фрагмента ацикловира, соединенных 4 цитрат-ионами и фрагментом аргинина) в отношении вируса простого герпеса 1-го типа (ВПГ-1, штамм «Кл») на модели менингоэнцефалита у аутбредных мышей. Ациклогерманий в диапазоне доз от 40 до 240 мг/кг вводили животным через 3 ч после инфицирования внутрь в объеме 0,2 мл ежедневно двукратно в течение 7 дней. Препарат сравнения — ацикловир. Оценивали: смертность, среднюю продолжительность жизни (СПЖ), уровень накопления вируса (инфекционная активность), изменение массы тела, коэффициент защиты (КЗ). Установлено, что ациклогерманий обладает дозозависимой активностью в отношении ВПГ-1, приводя к достоверному снижению смертности, увеличению СПЖ, снижению вирусной нагрузки в головном мозге животных, нормализации показателей массы тела. Наиболее выраженная (по сравнению с ацикловиром) эффективность была отмечена у ациклогермания в дозе 240 мг/кг: КЗ составил 72,2 %, СПЖ — 12,16 ± 1,1 сут, отмечалось значимое снижение смертности до 25 %, а также статистически достоверное снижение на 2,5 lg ТЦД50/0,1 мл (р < 0,05) инфекционной активности вируса в головном мозге животных. Ациклогерманий ингибировал репликацию вируса в головном мозге животных также эффективно, как и препарат сравнения ацикловир. На фоне применения ациклогермания динамика изменения массы тела инфицированных животных была более выраженной, ее показатели приближались к таковым у неинфицированных животных. Результаты исследования свидетельствуют о том, что введение в состав препарата германий-органического компонента позволило уменьшить эффективную дозу ацикловира.
Сравнительная характеристика действия дилепта и рисперидона у больных псевдоневротической шизофренией
Authors: Богданова Илона Олеговна , Сюняков Т. С. , Незнамов Г. Г. , Чепелюк А. А. , Коваленок Т. В. , Дорофеева О. А.
Published: September 2021

Проведен сравнительный анализ влияния нового психотропного средства пептидной природы дилепта и атипичного нейролептика рисперидона на психопатологические расстройства непсихотического уровня, негативные и когнитивные расстройства. Дилепт (200 мг в сутки) или рисперидон (2 мг в сутки): применяли 28 дней — 14 дней в монотерапии с однократными приемами феназепама (до 2 мг) при необходимости для коррекции усиления тревоги и расстройств сна, и с 15 дня в комбинации с феназепамом в дозах от 0,5 до 2 мг. Исследовано 25 больных в возрасте от 19 до 54 лет с диагнозом шизотипического расстройства и псевдоневротической шизофрении. Дилепт получали 15 пациентов, рисперидон — 10. Оба препарата влияли на основную псевдоневротическую симптоматику. В группе дилепта в сравнении с рисперидоном на 28 день не выявлено статистически значимых различий в динамике баллов по отдельным пунктам и суммарного балла по негативной подшкале шкалы PANSS и показателей сгруппированных симптомов оценки выраженности симптоматики, отражающих потенциальные анксиолитический, антигипотимический, антиастенический, психостимулирующий, антиневротический и миорелаксантный эффекты, но отмечалась статистически значимо более выраженное улучшение баллов по субтесту WAIS-R «Шифровка» (разница изменений: – 1,90 [– 3, 43; – 0, 36]). Дилепт является перспективным препаратом для дальнейшего изучения его терапевтической эффективности в клинических исследованиях II и III фаз в качестве средства монотерапии или в комбинации с основными препаратами у пациентов с расстройствами шизофренического спектра с преобладанием негативных и когнитивных расстройств.
Влияние цисплатина и гибридного оловоорганического соединения в малых дозах на рост и метастазирование эпидермоидной карциномы Lewis в эксперименте
Authors: Додохова Маргарита Авдеевна , Алхусейн – Кулягинова Маргарита Стефановна , Сафроненко Андрей Владимирович , Котиева Инга Мовлиевна , Шпаковский Дмитрий Борисович , Милаева Елена Рудольфовна
Published: September 2021

На модели перевиваемой опухоли эпидермоидной карциномы Lewis в экспериментах на мышах (самки) линии C57Bl/6 изучали противоопухолевое и антиметастатическое действие комбинированной терапии цисплатином и гибридным оловоорганическим соединением (Ме5) при курсовом внутрибрюшинном введении в малых дозах. Показано, что при пятикратном внутрибрюшинном введении исследуемых соединений в сочетанном режиме наблюдался синергический тип взаимодействия. На 21 сут после перевивки опухолевого материала у животных опытной группы размер первичного опухолевого узла уменьшился на 25 %, а также снизилась интенсивность метастазирования на 32 %, p ≤ 0,05.
Особенности фармакокинетики нафазолина при различных путях введения
Authors: Краев Сергей Юрьевич , Селезнёв А. Б. , Цой Д. В. , Алешина О. И. , Драчев И. С. , Никифоров А. С. , Иванов В. С.
Published: September 2021

Проведено сравнительное исследование фармакокинетики нафазолина при внутривенном, внутримышечном, внутрибрюшинном и интратрахеальном путях введения. Полученные результаты позволяют рассматривать интратрахеальный путь введения нафазолина как альтернативу внутрибрюшинному и внутримышечному путям введения, что может быть объяснено высокой биодоступностью и отсутствием эффекта «первого прохождения» через печень. Абсолютная биодоступность нафазолина при интратрахеальном введении составляет 94,3 %. Период полувыведения при интратрахеальном введении составлял 3,2 ч, клиренс — 0,8 л/ч, значения скорости всасывания и константы элиминации — 1,23 и 0,217 ч–1, соответственно.
Доклиническое исследование фармакокинетики инграмона
Authors: Карлина Марина Валерьевна , Косман Вера Михайловна , Арефьева Татьяна Игоревна , Сидорова Мария Владимировна , Дудкина Ульяна С. , Кискина Александра Романовна , Уколов Антон Игоревич , Макаров Валерий Геннадиевич
Published: September 2021

Инграмон представляет собой пептидный фрагмент (65 – 76) моноцитарного хемотаксического белка-1 (МСР-1) человека, обладающий противовоспалительной активностью. Фармакокинетические параметры инграмона после однократного внутримышечного введения кроликам в дозе 0,5 мг/кг составляют: Cmax = 840 ± 68 нг/мл, Tmax = 0,08 ± 0,00 ч, AUC0-8 = 981 ± 17 ч  нг/мл, AUC0-∞ = 1052 ± 16 ч  нг/мл, MRT = = 1,04 ± 0,04 ч, Т1/2 = 0,70 ± 0,02 ч.
Analysing the role of Saraswatarishta in the treatment of neurological disorders based on network pharmacology
Authors: Jethalia Vrinda , Hasyagar Sanjana Varada , Bhamidipati Kasturi , Chatterjee Jhinuk
Published: September 2021

Ayurvedic medications originated centuries ago and are still prevalent today. Saraswatarishta (SWRT) is a well-known ayurvedic formulation that is often prescribed to control the manifestations of neurological illnesses and disorders such as slurred speech, anxiety, Parkinson's disease (PD) and Alzheimer's disease(AD). However, scientific research on its mode of action has not been studied extensively. Therefore, this study employs network pharmacology to understand better the neuroprotective role of Saraswatarishta (SWRT) in neurological disorders. Out of the 18 ingredients in SWRT, five were considered in this study due to their elevated therapeutic action in neurological disorders. Further, nine active phytoconstituents were chosen from the five selected ingredients. The gene targets of the active phytoconstituents were screened and selected using STITCH, SwissTargetPrediction and ChEMBL. Protein-Protein interaction and Gene Ontology (GO) enrichment analysis were carried out using STRING and g:Profiler, respectively. Cytoscape 3.7.2 was used to create three networks-the compound-target, the target-disease and the compound-target-disease network. Molinspiration and admetSAR2.0 were used to obtain the bioactivity scores and the blood-brain barrier (BBB) probability scores. The three networks indicated that all nine phytoconstituents were linked to the gene targets that encode proteins involved in the pathways of 10 major neurological disorders. This includes Parkinson's disease (PD), Alzheimer's disease (AD), dementia, Huntington disease, epilepsy, schizophrenia, spinocerebellar ataxia, amyotrophic lateral sclerosis (ALS), multiple sclerosis and attention deficit hyperactivity disorder (ADHD).  The gene targets were expressed significantly in various central nervous system regions such as the cerebral cortex, cerebellum and amygdala. The bioactivity scores of the phytoconstituents were in the active range along with high BBB probability scores, indicating that the phytoconstituents can potentially cross the BBB and impart therapeutic effects.
University of Bradford Library Holding ISBN 9783110686074
Authors: Lab SDAG
Published: September 2021

University of Bradford Library Holding ISBN 9783110686074
Cat owners’ perceptions towards feline microchipping
Authors: Page Tara , Lewis Todd R , Read Lee
Published: September 2021

Compulsory feline microchipping has become a legal requirement in 2021 for domestic cats (Felis catus) in the UK, following the introduction of compulsory microchipping for dogs (Canis lupus familiaris) in 2016. The concept of compulsory feline microchipping attracts a combination of perceptions from the public, both positive and negative. An online survey was designed to obtain cat owners’ perception toward feline microchipping, evaluating attitudes and knowledge, and offering an opportunity for participants to provide insights into their reasoning for, or against, microchipping. Findings suggested that demographics are key predictors for influencing cat owners’ perception toward feline microchipping. In particular, men are less likely to formulate opinions regarding feline welfare and microchipping, and concern for feline welfare and empathy toward cats increases with age across both men and women. When asked to provide more details about their decision to microchip, or not microchip, the survey responses revealed 66% agent-centred reasoning compared to 24% welfare, suggesting that regardless of a person’s decision, reasoning was respectively agent-centred. This suggests that potential human benefits may influence cat owners’ perception toward feline microchipping. 75% of participants support compulsory microchipping. Of those who would not support the legislation, feline welfare concerns, and a negative outlook surrounding the current database and scanning processes that support microchipping, was revealed. A focus on addressing negative perceptions toward feline microchipping could highlight approaches to change cat owners’ perceptions toward the technique positively. The results herein are useful for feline welfare organisations to promote understanding about feline microchipping. Cite as: Page, T., Lewis, T.R. and Read, L. (2021). Cat owners’ perceptions towards feline microchipping. Kingston Maurward College, Specialist Research Project. 45pp. https://doi.org/10.31219/osf.io/4gbhe
University of Southampton Library Holding ISBN 9788366675599
Authors: Nguyen Minh-Hoang
Published: September 2021

https://www-lib.soton.ac.uk/uhtbin/cgisirsi/x/0/0/5/?searchdata1=9788366675599
Differential expression of ubiquitin specific peptidase 47 in human epithelial ovarian cancer.
Authors: Mamoor Shahan
Published: September 2021

Epithelial ovarian cancer (EOC) is the most lethal gynecologic cancer (1). We performed discovery of genes associated with epithelial ovarian cancer and of the high-grade serous ovarian cancer (HGSC) subtype, using published microarray data (2, 3) to compare global gene expression profiles of normal ovary or fallopian tube with that of primary tumors from women diagnosed with epithelial ovarian cancer or HGSC. We identified the gene encoding ubiquitin specific peptidase 47, USP47, as among the genes whose expression was most different in epithelial ovarian cancer as compared to the normal fallopian tube. USP47 expression was significantly lower in high-grade serous ovarian tumors relative to normal fallopian tube. These data indicate that expression of USP47 is perturbed in epithelial ovarian cancers broadly and in ovarian cancers of the HGSC subtype. USP47 may be relevant to pathways underlying ovarian cancer initiation (transformation) or progression.
Differential expression of von Willebrand factor C domain-containing 2 in human epithelial ovarian cancer.
Authors: Mamoor Shahan
Published: September 2021

Epithelial ovarian cancer (EOC) is the most lethal gynecologic cancer (1). We performed discovery of genes associated with epithelial ovarian cancer and of the high-grade serous ovarian cancer (HGSC) subtype, using published microarray data (2, 3) to compare global gene expression profiles of normal ovary or fallopian tube with that of primary tumors from women diagnosed with epithelial ovarian cancer or HGSC. We identified the gene encoding von Willebrand factor C domain-containing 2, VWC2, as among the genes whose expression was most different in epithelial ovarian cancer as compared to the normal fallopian tube. VWC2 expression was significantly lower in high-grade serous ovarian tumors relative to normal fallopian tube. VWC2 expression correlated with post-progression survival in patients with ovarian cancer. These data indicate that expression of VWC2 is perturbed in epithelial ovarian cancers broadly and in ovarian cancers of the HGSC subtype. VWC2 may be relevant to pathways underlying ovarian cancer initiation (transformation) or progression.
Looking back at the 2008-crisis lesson to help Vietnam’s stock market hold its attraction to investors
Authors: Nguyen Minh-Hoang
Published: September 2021

Implementing new economic plans, fiscal and monetary policies to help the economy recover in the new “normal stage” is important, but limiting the rise of inflation must not be neglected.
Landshut Univeristy of Applied Sciences Holding ISBN 9788366675599
Authors: Nguyen Minh-Hoang
Published: September 2021

Landshut Univeristy of Applied Sciences Holding ISBN 9788366675599
Differential expression of solute carrier family 24 member 3 in human epithelial ovarian cancer.
Authors: Mamoor Shahan
Published: September 2021

Epithelial ovarian cancer (EOC) is the most lethal gynecologic cancer (1). We performed discovery of genes associated with epithelial ovarian cancer and of the high-grade serous ovarian cancer (HGSC) subtype, using published microarray data (2, 3) to compare global gene expression profiles of normal ovary or fallopian tube with that of primary tumors from women diagnosed with epithelial ovarian cancer or HGSC. We identified the gene encoding solute carrier family 24 member 3, SLC24A3, as among the genes whose expression was most different in epithelial ovarian cancer as compared to the normal fallopian tube. SLC24A3 expression was significantly lower in high-grade serous ovarian tumors relative to normal fallopian tube. SLC24A3 expression correlated with overall survival in patients with ovarian cancer. These data indicate that expression of SLC24A3 is perturbed in epithelial ovarian cancers broadly and in ovarian cancers of the HGSC subtype. SLC24A3 may be relevant to pathways underlying ovarian cancer initiation (transformation) or progression.
Differential expression of MAM domain-containing 2 in human epithelial ovarian cancer.
Authors: Mamoor Shahan
Published: September 2021

Epithelial ovarian cancer (EOC) is the most lethal gynecologic cancer (1). We performed discovery of genes associated with epithelial ovarian cancer and of the high-grade serous ovarian cancer (HGSC) subtype, using published microarray data (2, 3) to compare global gene expression profiles of normal ovary or fallopian tube with that of primary tumors from women diagnosed with epithelial ovarian cancer or HGSC. We identified the gene encoding MAM domain-containing 2, MAMDC2, as among the genes whose expression was most different in epithelial ovarian cancer as compared to the normal fallopian tube. MAMDC2 expression was significantly lower in high-grade serous ovarian tumors relative to normal fallopian tube. MAMDC2 expression correlated with overall survival in patients with ovarian cancer. These data indicate that expression of MAMDC2 is perturbed in epithelial ovarian cancers broadly and in ovarian cancers of the HGSC subtype. MAMDC2 may be relevant to pathways underlying ovarian cancer initiation (transformation) or progression.
Universitätsbibliothek Marburg Holding ISBN 9788366675599
Authors: Le Tam-Tri
Published: September 2021

Universitätsbibliothek Marburg Holding ISBN 9788366675599
Differential expression of fatty acid hydroxylase domain-containing 2 in human epithelial ovarian cancer.
Authors: Mamoor Shahan
Published: September 2021

Epithelial ovarian cancer (EOC) is the most lethal gynecologic cancer (1). We performed discovery of genes associated with epithelial ovarian cancer and of the high-grade serous ovarian cancer (HGSC) subtype, using published microarray data (2, 3) to compare global gene expression profiles of normal ovary or fallopian tube with that of primary tumors from women diagnosed with epithelial ovarian cancer or HGSC. We identified the gene encoding fatty acid hydroxylase domain-containing 2, FAXDC2, as among the genes whose expression was most different in epithelial ovarian cancer as compared to the normal fallopian tube. FAXDC2 expression was significantly lower in high-grade serous ovarian tumors relative to normal fallopian tube. FAXDC2 expression correlated with progression-free survival in patients with ovarian cancer. These data indicate that expression of FAXDC2 is perturbed in epithelial ovarian cancers broadly and in ovarian cancers of the HGSC subtype. FAXDC2 may be relevant to pathways underlying ovarian cancer initiation (transformation) or progression.
Katalog der Hochschul- und Kreisbibliothek Bonn-Rhein-Sieg Holding ISBN 9788366675599
Authors: Nguyen Minh-Hoang
Published: September 2021

https://bib-sisis.bib.hochschule-bonn-rhein-sieg.de/webOPACClient/start.do?Language=De&Login=opacsta&Query=0%3D%22751419%22
HAORNAS: Gerakan Sport for All Kunci Keberhasilan Olahraga Indonesia
Authors: Rahadian Adi
Published: September 2021

Haornas merupakan momentum keberhasilan olahraga, yang digambarkan sebagai simbol kebangkitan nasional dan juara olahraga menjadi ikon nasional. Hal ini merupakan pembudayaan olahraga yang dilakukan secara koheren, terpadu, dan berkesinambungan. Tujuan dari penelitian ini adalah untuk mendeskripsikan serta mengungkap sejarah yang berkaitan dengan catatan perjalanan Haornas beserta perkembangan olahraga di Indonesia. Pendekatan kualitatif dengan deskriptif eksploratif dipilih dalam penelitian ini. Partisipan berjumlah 8 responden, terdiri dari pejabat publik, akademisi, atlet, dan masyarakat, yang diambil dengan menggunakan teknik qualitative purposive sampling. Lokasi bertempat di wilayah DKI Jakarta dan Jawa Barat, pelaksanaan pada bulan Juli-Agustus. Observasi dan wawancara semi terstruktur digunakan dalam pengumpulan data. Temuan ini menunjukkan bahwa upaya olahraga untuk semua, mengintegrasikan jalur pembinaan dan pengembangan olahraga di Indonesia yang mengarah kepada pergeseran paradigma dari ‘pengembangan olahraga’ menjadi ‘pengembangan melalui olahraga. Dengan demikian, olahraga sebagai instrumen pembangunan yang berpotensi meningkatkan kualitas hidup masyarakat Indonesia. Sehingga, peringatan Haornas dengan gerakan “sport for all” perlu dikembangkan menjadi pembangkit budaya olahraga di tanah air.
Justus-Liebig-Universität Gießen Library Holding ISBN 9788366675599
Authors: Nguyen Minh-Hoang
Published: September 2021

https://hds.hebis.de/ubgi/Record/HEB484063863
Hanny Siagian
Authors: PEMBANGUNAN GOVERNANCE: JURNAL POLITIK LOKAL DAN
Published: September 2021

Urban Village has the main task of carrying out government, development and community affairs (article 4 paragraph 1 of the Republic of Indonesia Government Regulation No. 73 of 2005 concerning Urban Village). The community's demands for good public services cannot be separated from the existence of the urban village which is very close to the local residents. The complaints that arise from local residents indicate that the service is still not satisfactory in terms of speed of completion of work in administrative matters, this is related to the ability and motivation of Human Resources (employees).Extension activities provide education in the form of lectures and discussions as well as evaluation of knowledge before and after counseling. The results of the extension activities showed that there was an increase in additional knowledge of 25.11% after the extension was carried out. It is hoped that this counseling activity can be sustainable in an effort to improve work skills and motivation to improve employee performance in providing services to the community in accordance with the duties and functions of the urban village.
Differential expression of RAS-like estrogen regulated growth inhibitor in human epithelial ovarian cancer.
Authors: Mamoor Shahan
Published: September 2021

Epithelial ovarian cancer (EOC) is the most lethal gynecologic cancer (1). We performed discovery of genes associated with epithelial ovarian cancer and of the high-grade serous ovarian cancer (HGSC) subtype, using published and public microarray data (2, 3) to compare global gene expression profiles of normal ovary or fallopian tube with that of primary tumors from women diagnosed with epithelial ovarian cancer or HGSC. We identified the gene encoding RAS-like estrogen regulated growth inhibitor, RERG, as among the genes whose expression was most different in epithelial ovarian cancer as compared to the normal fallopian tube. RERG expression was significantly lower in high-grade serous ovarian tumors relative to normal fallopian tube. In a separate dataset, we discovered significant differential expression of a non-coding RNA transcribed from the RERG locus, RERG-AS1, in the tumors of patients with epithelial ovarian cancer when comparing tumors based on disease progression. RERG expression correlated with progression-free survival in patients with ovarian cancer. These data indicate that expression of RERG is perturbed in epithelial ovarian cancers broadly and in ovarian cancers of the HGSC subtype. RERG may be relevant to pathways underlying ovarian cancer initiation (transformation) or progression.
关于经典电磁理论里电场强度、运动速度具体含义的实验构想
Authors: YANG Zheng-Ling
Published: September 2021

在面积无限大的磁感应强度为有限值的均匀磁场里运动的导体，会感受到磁场的变化，从而产生感生电势。类似地，在面积无限大的电场强度为有限值的均匀电场里运动的电荷或载流导线，是否会感受到电场的变化？进而受到电场变化引起的磁力作用？
Strategi Madrasah Swasta Mewujudkan Lembaga Pendidikan Bermutu: Kasus Madrasah Pembangunan Ciputat
Authors: Murtadlo Muhamad
Published: September 2021

Madrasah di Indonesia sering diidentikkan dengan lembaga pendidikan yang penuh keterbatasan. namun belakangan ada beberapa madrasah swasta yang berhasil menjadi sekolah unggulan dan berhasil menarik minat masyarakat kelas menengah kota. salah satu madrasah itu adalah Madrasah Pembangunan Ciputat Tangerang Selatan. Studi ini bermaksud mengkaji usaha madrasah swasta ini menjadi sekolah unggulan dengan pendekatan studi kasus. Studi ini menemukan bahwa Madrasah Pembangunan Ciputat menerapkan pendekatan multi dimensi, atau yang sering disebut sebagai Total Quality Management.
University College London Library Holding ISBN 9788366675599
Authors: Lab SDAG
Published: September 2021

University College London Library Holding ISBN 9788366675599
数学中“任意量”的定义与运算
Authors: YANG Zheng-Ling
Published: September 2021

在数学里，仿照无穷大（infinity）及其运算规则，定义了任意量（anyity）及其运算规则。这是对电气工程里“理想电流源串联电阻的等效计算”的数学提炼。
Differential expression of myomesin 1 in human epithelial ovarian cancer.
Authors: Mamoor Shahan
Published: September 2021

Epithelial ovarian cancer (EOC) is the most lethal gynecologic cancer (1). We performed discovery of genes associated with epithelial ovarian cancer and of the high-grade serous ovarian cancer (HGSC) subtype, using published microarray data (2, 3) to compare global gene expression profiles of normal ovary or fallopian tube with that of primary tumors from women diagnosed with epithelial ovarian cancer or HGSC. We identified the gene encoding myomesin 1, MYOM1, as among the genes whose expression was most different in epithelial ovarian cancer as compared to the normal fallopian tube. MYOM1 expression was significantly lower in high-grade serous ovarian tumors relative to normal fallopian tube. MYOM1 expression correlated with progression-free survival in patients with ovarian cancer. These data indicate that expression of MYOM1 is perturbed in epithelial ovarian cancers broadly and in ovarian cancers of the HGSC subtype. MYOM1 may be relevant to pathways underlying ovarian cancer initiation (transformation) or progression.
LIBRIS Holding ISBN 9788366675599
Authors: Le Tam-Tri
Published: September 2021

LIBRIS Holding ISBN 9788366675599
BUKU AJAR KOMUNIKASI BISNIS
Authors: Daga Rosnaini
Published: September 2021

Penerbitan buku ajar ini, merupakan bagian dalam mengupayakan tumbuhnya iklim akademik. Dimana dengan penulisan buku ajar, setiap kelas yang diampuh dosen memiliki tipikal tersendiri. Olehnya, penerbitan buku aja akan memperkaya pembelajaran masing?masing dosen. Pada saat yang sama, dengan adanya buku ajar akan memudahkan dosen dalam mengelola kelasnya masing-masing. Tetap saja memunginkan untuk menggunakan buku ajar dari perguruan tinggi atau dosen lain. Hanya saja, ketika masing-masing dosen menerbitkan buku ajarnya akan menjadi sebuah instrumen dalam pembelajaran. Secara perlahan ekosistem keilmuan akan tumbuh. Pada saat yang sama, dosen akan memutakhirkan bukunya secara terus menerus
Differential expression of potassium calcium-activated channel subfamily N member 3 in human epithelial ovarian cancer.
Authors: Mamoor Shahan
Published: September 2021

Epithelial ovarian cancer (EOC) is the most lethal gynecologic cancer (1). We performed discovery of genes associated with epithelial ovarian cancer and of the high-grade serous ovarian cancer (HGSC) subtype, using published microarray data (2, 3) to compare global gene expression profiles of normal ovary or fallopian tube with that of primary tumors from women diagnosed with epithelial ovarian cancer or HGSC. We identified the gene encoding potassium calcium-activated channel subfamily N member 3, KCNN3, as among the genes whose expression was most different in epithelial ovarian cancer as compared to the normal fallopian tube. KCNN3 expression was significantly lower in high-grade serous ovarian tumors relative to normal fallopian tube. KCNN3 expression correlated with overall survival in patients with ovarian cancer. These data indicate that expression of KCNN3 is perturbed in epithelial ovarian cancers broadly and in ovarian cancers of the HGSC subtype. KCNN3 may be relevant to pathways underlying ovarian cancer initiation (transformation) or progression.
Voted In, Standing Out: Public Response to Immigrants' Political Accession
Authors: Grossman Guy , Zonszein Stephanie
Published: September 2021

How do dominant-group natives react to immigrants' political integration? We argue that ethnic minority immigrants winning political office makes natives feel threatened, triggering animosity. We test this dynamic across the 2010--2019 UK general elections, using hate crime police records, public opinion data, and text data from over 500,000 regional and local newspaper articles. While past work has not established a causal relationship between minorities' political power gains and dominant group animosity, we identify natives’ hostile reactions with a regression discontinuity design that leverages close election results between immigrant-origin ethnic minority and dominant-group candidates. We find that minority victories increase hate crimes by 68%, exclusionary attitudes by 66%, and negative media coverage of immigrant groups by 110%. Consistent with power threat and social identity theories, these findings demonstrate a strong and widespread negative reaction---encompassing a violence-prone fringe and the mass public---against ethnic minority immigrants' integration into majority settings.
Universitätsbibliothek München Holding ISBN 9788366675599
Authors: Lab SDAG
Published: September 2021

Universitätsbibliothek München Holding ISBN 9788366675599.pdf
The evolution of triple junctions: from failure to success
Authors: Khalil Hany , Capitanio Fabio , Cruden Alexander
Published: September 2021

Divergent triple junctions are stable plate margins where three spreading ridges meet. Although it is accepted that this configuration is inherited from an earlier phase of continental rifting, how post-breakup triple junctions emerge from the separation of two plates remains unclear. By documenting the strain rate history recorded in the three rift-arms of several modern and ancient triple junctions, we show that deformation is episodic and localized in only one or two rifts at any given time. We further investigate this behavior in three-dimensional (3D) analog experiments of rifting, under a range of kinematic boundary conditions and containing a variety of pre-existing lithospheric heterogeneities. Deformation in the experiments is characterized by strain jumps and rift abandonment, comparable to natural observations. Boundary rotation during extension induces oblique stretching directions, along-strike strain gradients and forces significant strain jump to reduce the number of rifts segments active. Models that comprise lithospheres ranging from homogenous to containing a triple junction-like pre-existing heterogeneities, never developed a three-armed rift, where all rift segments are active at same time, at any stage. Our experimental results indicate that, unlike mature, successful, and stable oceanic triple junctions, early-stage continental rifting progresses through unstable “double-junctions” characterized by repeated strain jumps and rift failures and reactivations.
Economic inequality increases race salience in 6 million Tweets
Authors: McGovern Hugh , Kirkland Kelly , Blake Khandis
Published: September 2021

Economic inequality brings multiple adverse consequences. These range from decreased trust in government, increased drug abuse and violence, and decreased societal cohesion. If and how economic inequality impacts online behaviors has received less attention. Here, we use a corpus of 6 million race tweets posted between 2012 and 2018 to determine the frequency and sentiment of tweets containing ethnic epithets and slurs across all 52 US states. Informed by Integrated Threat Theory, we tested whether inequality increased the use of slurs on social media for the purpose of denigrating other ethnic groups. Consistent with this, we found that states with greater inequality predicted increased use of racial epithets used to denigrate other groups. However, we also found that more unequal locales were positively correlated with increased use of ethnic words used in a positive way (potentially toward other ingroup members). As such, while inequality is correlated with more prejudicial behavior on social media, it may also increase the salience of ethnic group identity more broadly. Implications and future directions are discussed.
Political Identity Biases Americans’ Judgments of Outgroup Emotion
Authors: Basyouni Ruby , Harp Nicholas , Haas Ingrid Johnsen , Neta Maital
Published: September 2021

Social group identity plays a central role in political polarization and inter-party conflict. Here, we use ambiguously valenced faces to measure bias in the processing of political ingroup and outgroup faces, while also accounting for interparty differences in judgments of emotion at baseline. Participants identifying as Democrats and Republicans judged happy, angry, and surprised faces as positive or negative. Whereas happy and angry faces convey positive and negative valence respectively, surprised faces are ambiguous in that they readily convey positive and negative valence. Thus, surprise is a useful tool for characterizing valence bias (i.e., the tendency to judge ambiguous stimuli as negative). Face stimuli were assigned to the participants’ political ingroup or outgroup, or a third group with an unspecified affiliation (baseline). We found a significant interaction of facial expression and group membership, such that outgroup faces were judged more negatively than ingroup and baseline, but only for surprise. There was also an interaction of facial expression and political affiliation, with Republicans judging surprise more negatively than Democrats across all group conditions. However, we did not find evidence for party differences in outgroup negativity. Our findings demonstrate the utility of judgments of surprised faces as a measure of intergroup bias, and reinforce the importance of outgroup negativity (relative to ingroup positivity) for explaining inter-party biases.
The Bouba-Kiki effect is predicted by sound properties but not speech properties
Authors: Passi Ananya , Arun SP
Published: September 2021

Humans robustly associate spiky shapes to words like “Kiki” and round shapes to words like “Bouba”. A popular explanation is that the mouth forms an angular shape while saying “Kiki” and a rounded shape while saying “Bouba”, leading to this association. Alternatively, there could be generic associations between the shapes of objects and the sounds they produce. These possibilities can be distinguished using unpronounceable sounds: the mouth-shape hypothesis predicts no effect, whereas the generic shape hypothesis predicts a systematic effect. Here, we show that the Bouba-Kiki effect is present for a variety of unpronounceable sounds ranging from reversed versions of Bouba-like and Kiki-like words and natural real object sounds to even pure tones. The effect was strongly correlated with the mean frequency of a sound independent of its pronounceability. Thus, the Bouba-Kiki effect reflects generic associations between sounds and object shape rather than mouth shape.
Neural Mechanisms and Psychology of Psychedelic Ego Dissolution
Authors: Stoliker Devon , Egan Gary F. , Friston Karl , Razi Adeel
Published: September 2021

Neuroimaging studies of psychedelics have advanced our understanding of hierarchical brain organisation and the mechanisms underlying their subjective and therapeutic effects. The primary mechanism of action of classic psychedelics is binding to serotonergic 5HT2A receptors. Agonist activity at these receptors leads to neuromodulatory changes in synaptic efficacy that can have a profound effect on hierarchical message passing in the brain. Here, we review the cognitive and neuroimaging evidence for the effects of psychedelics; in particular, their influence on selfhood and subject-object boundaries—known as ego dissolution—surmised to underwrite their subjective and therapeutic effects. Agonist of 5HT2A receptors, located at the apex of the cortical hierarchy may have a particularly powerful effect on sentience and consciousness. These effects can endure well after the pharmacological half life, suggesting that psychedelics may have long-term effects on neural plasticity – that may play a role in their therapeutic efficacy. Psychologically, this may be accompanied by a surrender of ego resistance that increases the repertoire of perceptual hypotheses, including those that undergird selfhood. We consider the interaction between serotonergic neuromodulation and sentience through the lens of hierarchical predictive coding, which speaks to the value of psychedelics in understanding how we make sense of the world—and specific predictions about effective connectivity in cortical hierarchies that can be tested using functional neuroimaging.