bluuebunny/crossref_metadata_2025 huggingface dataset:
Neurocognitive Implications in Children Undergoing Chemotherapy and Radiotherapy
Authors: Vieira Natália Barros Salgado , Pereira Sarah Joanny da Silva , Castro Ana Flávia Silva
Published: December 2021

Background: Radiotherapy and chemotherapy drugs were essential for increasing the survival rates of pediatric cancer patients, but dysfunctions associated with treatment, mainly neurological and cognitive, are recorded and should be considered in deciding the therapeutic plan. Objectives: Analyze the current literature on the neurocognitive effects in children undergoing chemotherapy and radiation therapy. Methods: A bibliographic review was carried out in the MEDLINE / Pubmed and LILACS databases, using the terms “cognitive effects”, “chemotherapy”, “radiotherapy” and “child”, in Portuguese and in English. 79 articles were found and 6 followed for complete analysis. Articles published more than 5 years ago and that did not address the proposed subject were not used. Results: Radiotherapy, especially cranial (CRT), is associated with serious effects, such as induction of vasculopathy, stroke, cerebrovascular malformations, in addition to an increased risk for subsequent malignant CNS tumors. Despite being a standard treatment for several neoplasms, radiotherapy has been replaced, when possible, by higher doses of chemotherapy, which has a considerable level of neurotoxicity, capable of causing coagulopathy, encephalopathy, seizures and neuropathies, both sensory and motor. However, deficits in children’s attentional capacity in both treatment categories stood out, sometimes implying educational difficulties and decline in non-verbal skills. Conclusions: Although chemotherapy and radiation therapy represent impressive advances, their consequences remain a concern. Future studies should seek strategies for prevention, early recognition and management of neurotoxicity, in order to promote better life quality for patients.
Lambert-Eaton syndrome without an identified neoplasm
Authors: Carvalho Ana Cláudia Pires , Trivellato Stella Angelis , Anastacio Guilherme Jardini Drumond , Dias Fernanda Rezende , Costa Luisa Crevelin , Akita Juliana , Nakao Natália de Castro Fim
Published: December 2021

Introduction: Lambert-Eaton syndrome occurs due to the attack of autoantibodies to voltage-gated calcium channels in the presynaptic terminal of the neuromuscular junction and is usually paraneoplastic. Objectives: Describe the case of a patient with weakness which was investigated for neoplasm. Design and setting: Case report Methods: Analysis of medical record, photographic record of the diagnostic methods and literature review. Case description: Woman, 60 years old, diabetic, hypertensive and ex-smoker, with proximal weakness in the lower limbs for 4 months with paresthesia in the extremities. In 2 months she needed a cane due to frequent falls, followed by proximal weakness of the upper limbs. She lost 8 kg in 4 months. Neurological examination showed hypotrophy in thighs, proximal tetraparesis predominantly in lower limbs and global hyporeflexia. Electroneuromyography showed decreases to repetitive low-frequency stimulation, but significant increases with repetitive high-frequency stimulation and increased amplitude of compound muscle action potentials after effort, suggesting impairment of the neuromuscular junction in the presynaptic topography. She was diagnosed with LambertEaton syndrome. An investigation of paraneoplastic syndrome was carried out, with tumor markers, tomography of the chest, abdomen and pelvis, thyroid ultrasound, mammography and oncotic colposcopy, all without findings of neoplasia. It was proposed a treatment with human immunoglobulin and followup with physiotherapy, occupational therapy and psychology. She showed a significant improvement in strength after starting treatment. Conclusion: Patients with Lambert-Eaton syndrome should be investigated for an underlying neoplasm and followed up periodically, considering the possibility of cancer diagnosis even months or years after the neurological syndrome.
An Unexpected Smile: risus sardonicus and wing-beating tremor in a first office visit
Authors: Filpo Alessandra , Disserol Caio , Teixeira Bernardo Corrêa de Almeida , Hokazono Kenzo , Teive Hélio A. G.
Published: December 2021

Context: We present a noteworthy reminder of Wilson disease’s classical manifestations, which may become rarer in clinical practice as availability of genetic tests increases, allowing timely diagnosis and treatment. Case report: A 29 year-old woman developed progressive and asymmetric upper limb tremor and dystonia over 1 year, along with speech and feeding impairment in the last two weeks. Examination revealed segmental dystonia with risus sardonicus, open-jaw oromandibular and severe left arm dystonia, along with wing-beating tremor. Bilateral Kayser-Fleischer ring, low serum ceruloplasmin level, high urinary copper level, bilateral putaminal lesions on brain MRI and detection of ATP7B mutation confirmed Wilson disease (WD). A nasoenteric tube was inserted and D-penicillamine was started. Conclusion: This case illustrates the hallmark neuro-ophtalmological signs of WD: wing-beating tremor, risus sardonicus and Kayser-Fleischer ring. The former is probably associated with lesions in the dentato-rubro-thalamic pathway¹ and means a low frequency, high amplitude, posture-induced proximal arm tremor. Risus sardonicus means a fixed smile due to risorius muscle dystonia². Although it is a well-known manifestation of cephalic tetanus, it is also frequent in WD¹. Finally, the Kayser-Fleischer ring is caused by copper accumulation in the Descemet membrane and occurs in almost 100% of patients with neurological WD².
Successful treatment with rituximab in a refractory Stiffperson syndrome (SPS)
Authors: Damasceno Júnior Eustáquio Costa , Borges Isabella Sabião , Moreira João Victor Aguiar , Aguiar Pedro Otávio Rego de , Ferreira Thaciany Soares , Garcia Leonardo Peixoto , Pacheco Glauber Mota , Oliveira Clarice Pereira Sales , Alves Gabriela Tomás , Maciel Pedro Henrique Pereira , Fernandes João Paulo Moreira , Santos Alencar Pereira dos , Bueno Mateus Barros , Souza Rafael Lopes de , Silvestre Leonardo Rivelli , Oliveira Thales Junqueira , Assunção Gabriel Nunes Melo , Rosa Maria Fernanda Prado , Goulart Isabela Maria Bernardes , Santos Diogo Fernandes dos
Published: December 2021

Background: SPS is a disorder consisting of rigidity of axial muscles with painful spasms. More than 80 % of SPS patients have high titer antibodies against glutamic acid decarboxylase (GAD). The use of rituximab for the treatment of SPS is a recent therapeutical approach showing promising results. We present a case of SPS treated with rituximab, showing a good and safe response. Case: A 38-year-old female patient presented with a history of rigidity of abdominal and paravertebral muscles associated with painful spasms in lower back region, increased tonus, lumbar lordosis, frequent falls and severe functional limitation. The anti-GAD antibodies were positive in high titles. Electromyography showed continuous motor activity with normal morphology especially on paravertebral muscles. She had a partial response to baclofen and diazepam, but could not tolerate it because of somnolence, and started the treatment with rituximab. After one year, the baclofen was discontinued and the diazepam reduced. The axial stiffness and spasm frequency improved, including postural instability, without new episodes of falls. Discussion: Rituximab is a monoclonal antibody targeting the CD20 antigens on the surface of mature B lymphocytes. After binding to these antigens, it initiates a cascade of biochemical events leading to apoptosis. Its use has been approved for numerous diseases with promising results. The use of rituximab in the treatment of SPS is a recent approach and good results have been reported. Conclusion: Rituximab may be a promising option in SPS treatment. However, this is a preliminary paper showing partial results requiring long-term follow-up.
Comparison of 4% Topical Hydroquinone versus Combination of Oral Tranexamic Acid and 4% Topical Hydroquinone in the Treatment of Epidermal Melasma
Authors: Riaz Sarah , Ahmed Najia , Anwar Ayesha , Tahir Moizza , Yousaf Farrah , Kausar Sameena
Published: December 2021

Objective: comparison of efficacy of topical 4% hydroquinone monotherapy with combination of oral tranexamic acid and topical 4% hydroquinone in the treatment of epidermal melasma Study design: Quasi experimental study Study period and place: Dermatology OPD, Pak Emirates Military Hospital Rawalpindi from July 2018 to January 2019. Methodology: Total 80 patients presenting with epidermal melasma were selected from outdoor patient department after applying the inclusion criteria and consent was taken from selected patients. Study was started after getting permission from hospital ethical review board. Two treatment groups were made after dividing patients by using alternate method. Treatment with topical 4% hydroquinone alone was started for group A patients and combination of capsule tranexamic acid (250 mg two times a day) along with topical 4% hydroquinone were started for group B patients for the next 6 months. Evaluation of patients through detailed history, clinical and wood’s light examination before starting therapy and after of 24 weeks of treatment was done for both groups. Efficacy of treatment was assessed via Modified MASI score. Results: Hydroquinone monotherapy was effective in 21 (52.5%) patients among group A while in group B patients, combination treatment i.e. oral tranexamic acid and topical hydroquinone, was effective in 31 (77.5%) patients (p value= 0.01). Conclusion: Effectiveness of Hydroquinone 4% topical therapy combined with oral tranexamic acid for epidermal melasma is better than topical 4% hydroquinone alone. Key words: Epidermal melasma, oral tranexamic acid, topical 4% hydroquinone.
Investigation of The Relationship Between The Life Quality and Life Satisfactions of Karate Do Coaches in The Covid-19 Outbreak Process
Authors: Gökdere Fuat , Şarvan Cengiz Şebnem
Published: December 2021

Aim: The aim of the study is to report the quality of life and life satisfaction of karate-do trainers during the covid-19 epidemic and public health restrictions, and to examine the relationships between trainers' quality of life and life satisfaction while the restrictions persist. Methods: During public health restrictions, Karate Do trainers were recruited through an online survey and social media posting of demographics, quality of life, and life satisfaction sections. The World Health Organization Quality of Life Scale (WHOQOL-BREF) and the 7-point Likert-type Life Satisfaction Scale developed by Diener et al. (1985) and validated in Turkish by Bekmezci and Mert (2018) were used. IBM SPSS 22 package was used for data analysis. Independent Sample T test, One way Anova Test and Pearson Correlation Test were used with the program. The significance level of all evaluations was taken into account as p<0.05. Results: In the findings obtained in the study, no significant difference was found between the participants' gender, age, educational status, residence and coaching time, and life satisfaction in the sub-dimensions of quality of life. A significant difference was found between the monthly income levels of the participants and the sub-dimensions of the quality of life, namely the psychological field and the environmental field and life satisfaction. During the pandemic period, significant differences were observed in the levels of paying attention to mask-distance-hygiene rules and in all sub-dimensions of quality of life. As a result of the correlation analysis, it was observed that as the quality of life of karate do trainers increased, life satisfaction at the mid-low level increased positively. Conclusion: No significant difference was found between the variables of gender, age, education level, residence and duration of coaching of karate do trainers and quality of life and life satisfaction. It was observed that there was a significant difference between the monthly income of the trainers and the sub-dimensions of the quality of life, namely psychological domain, environmental domain and life satisfaction. As karate do trainers pay attention to hygiene rules in every period, significant differences were observed between the level of attention to mask-distance-hygiene rules and all sub-dimensions of quality of life during the pandemic period. From this point of view, it can be said that Karate Do trainers pay attention to hygiene rules, especially during the pandemic period. In our study, it was observed that as the quality of life of Karate Do trainers increased, their life satisfaction also increased moderately positively. It is predicted that this ratio will increase even more with the new regulations to be made on the living standards and personal rights of Karate Do trainers. Keywords: Covid-19, Karate Trainers, Quality of Life, Life Satisfaction.
Investigation of Special Education and Branch Teachers' Attitudes Towards Physical Education and Sports Activities of Individuals with Special Needs
Authors: Baş Mustafa , Ün Yeşim , Özsandikçi Kübra , Terzioğlu Ece Selen
Published: December 2021

The aim of this research is to examine the attitudes of special education and branch teachers towards physical education and sports activities of individuals who need special education. The sample of study consists of a total of 40 volunteer teachers, 28 female and 12 male, who work as special education and branch teachers at Rize Zehra Usta Special Education Practice School in the spring term of the 2020-2021 academic year. "Personal Information Form", which was developed by the researcher by taking expert opinion, and "Attitude towards Sports Activities of Individuals with Intellectual Disabilities Scale (ATSAIIDS)" developed by İlhan, Esentürk, and Yarımkaya (2016) were used as data collection tools in the research. Survey model, one of the quantitative research designs, was used in the research. SPSS 21.00 statistics program was used in the analysis of the research data. In the findings obtained, a significant relationship was found in terms of the variable of department (branch) from which the participants graduated. It was determined that the attitude levels of the employees who graduated from other departments were higher than those who graduated from the special education department. However, no significant relationship was found in terms of gender, age, education level, having a disabled person in their family, and receiving sports training for the disabled. Keywords: Attitude, intellectual disability, special education, physical education and sports
Seropositivity of Hepatitis B & C Virus in Surgical Patients Undergoing Elective & Emergency General Surgery
Authors: Ahmad Aqeel , Yousaf Imran , Tahir Shah Syed Muhammad , Rizwan Qadir Muhammad , Gulzar Arif , Hussain Khan Abid
Published: December 2021

Aim: To assess the seropositive cases of hepatitis B & C in surgical patients admitted for both emergency & elective surgery. Methodology: This study was conducted in the surgery department of Pak Red Crescent Teaching Hospital. The design of the study was descriptive observational. All the 1238 patients undergoing emergency and elective surgery were enrolled in this study by convenient sampling. Demographic data of all the patients were recorded. Along with routine preoperative tests, all the patients were screened for hepatitis B & C virus infection. Immunochromatography (ICT) method was adopted for both HBsAg and Anti-HCV screening. In patients with week positive results further test of enzyme-linked immunosorbent assay (ELISA) was performed. Operation theater staff and surgeon were informed about seropositive patients to take special precautionary measures during handling of the sharp objects. Biological waste of such patients is disposed of by using Biosafety protocols. Demographic data along with risk factors, HbsAg & Anti-HCV status were collected and analyzed with Microsoft Excel 2019. Results: A total number of 1238 patients were enrolled in our study, out of them 708 were male and 530 were female. Average age of the patients was 40.05±16 years. Out of 1238 patients, HBV was found in 14(1.13%) patients and HCV was found in 121 (9.77%) patients both hepatitis B & C was found in 3(0.24%) patients. Conclusion: Preoperatively screening of hepatitis B and C should be performed mandatory in all patients regardless of the nature of surgery. Before operating seropositive patients, surgeon and operation theater staff should be informed to take precautionary measures while handling the sharp objects. Used infected material of such patients should be disposed of by using Biosafety protocols. All the health works must be vaccinated against hepatitis B virus. Keywords: Hep B infection, Hep C Infection, Seropositive.
APLICAÇÃO DE CLUSTERIZAÇÃO NA ANÁLISE DE PUBLICAÇÕES CIENTÍFICAS SOBRE RADIOLOGIA NO PERÍODO DA COVID-19
Authors: De Medeiros Caroline , Miranda Júnior Jaime , Pires de Pires Denise Elvira , Todesco  José Leomar , Artur de Souza João
Published: December 2021

Este estudo apresenta os resultados de uma pesquisa aplicada que teve a finalidade de identificar e analisar o que a comunidade científica mundial está publicando sobre os temas radiologia e diagnóstico por imagem no período da pandemia causada pelo vírus da COVID-19, a pandemia causada pelo novo coronavírus colocou em evidência o papel fundamental da radiologia e diagnóstico por imagem, e a importância que os profissionais da saúde desempenham na sociedade. No estudo foram analisados 568 estudos extraídos na base de dados Scopus com os descritores "radiology and imaging diagnosis" e "COVID-19". A análise foi realizada por meio da ferramenta Orange Canvas mediante a técnica de clusterização. Como resultado, foi descoberto que os estudos estão direcionados para protocolos de radiologia para diagnóstico, gestão e processos básicos de trabalho da radiologia em suas atividades diárias. Um mapa mental foi proposto, a fim de sintetizar o agrupamento das descobertas dos estudos e também nesta síntese as evidências da falta de preocupação com a saúde do trabalhador de radiologia no momento da pandemia.
‘Every Move You Make … Every Word You Say’: Regulating Police Body Worn Cameras
Authors: Blewer Robyn , Behlau Ron
Published: December 2021

The death of Minneapolis man, George Floyd, at the hands (or, knee) of a police officer in May 2020 appears to have set a nation, indeed the world, alight with outrage at ongoing, systemic racism and brutality by police officers. Body worn camera (‘BWC’) footage from officers attending this incident provides strong evidence of the circumstances of Mr Floyd’s death. In this article, we draw on criminological research and analyses of legislation in Australia and a number of international jurisdictions, to argue there is a need for improved regulation of BWCs. Despite incurring the substantial cost of deploying this technology, governments are relinquishing control of it to law enforcement agencies who, in turn, draft policies that maximise police discretion and protection while minimising the consequences of non-compliance. For governments to realise their objectives for BWCs, we argue there is a need for greater regulation to ensure BWCs are utilised effectively.
Digital Democracy: Big Technology and the Regulation of Politics
Authors: Gauja Anika
Published: December 2021

The legal regulation of politics has, at its core, the aim of preserving three fundamental democratic values: liberty, equality and deliberative political participation. Yet, the reference point for examining these values is rooted in 19th and 20th century practices: where political campaigning and mobilisation follow terrestrial principles of organisation and regulation is undertaken by the state. Using the most recent empirical evidence drawn from political science on the changing nature of political participation and organisation, this article analyses the challenges of regulating digital politics. It argues that while the major focus of current interventions centres on political disinformation, this obscures more fundamental regulatory concerns such as capturing the diversity of new modes of participation and reconceptualising equality. While a model of co-regulation holds promise by institutionalising communities and individuals within technology companies’ policy decision-making processes, firms’ ultimate authority to define and control their user base presents challenges for effective participation.
Adtech and Children’s Data Rights
Authors: Archbold Lisa , Clifford Damian , Paterson Moira , Richardson Megan , Witzleb Normann
Published: December 2021

The advertising technology industry, known as ‘adtech’, is a complicated network of organisations and individuals that collect, aggregate and deal with large amounts of personal data. As children engage with digital networks for many aspects of their lives, they are increasingly exposed to adtech practices. Depending on their age, children may have less knowledge of the commercial digital environment and less maturity in their decision-making processes than adults have. Their limited resilience in the face of adtech’s onslaught offers a particularly stark illustration of why it is problematic to look to ‘consent’ as the exclusive or predominant mechanism to control the use of consumer data in the digital ecosystem. This article examines the problems arising from adtech’s data practices and makes recommendations on how to strengthen the agency and control exercised by children and protect their best interests in the context of adtech.
Growing Enlightenment: Sentencing Offenders with Autism Spectrum Disorder in Australia
Authors: Wolf Gabrielle
Published: December 2021

The number of defendants raising an Autism Spectrum Disorder (‘ASD’) diagnosis in criminal proceedings is increasing. Australian courts treat this neurodevelopmental disorder as a mental impairment that they may take into account in sentencing. A few studies nonetheless exposed deficiencies in judicial officers’ understanding of ASD symptoms and their potential forensic relevance. Courts’ willingness to rely on expert evidence did not always lead to them sentencing offenders with ASD in a consistent or enlightened manner. Building on those investigations and drawing on research into ASD, this article examines sentencing decisions involving eight offenders with ASD in various Australian jurisdictions between 2014 and 2020. This analysis demonstrates that judicial officers’ knowledge about ASD and appreciation of its possible relevance to sentencing considerations are growing, but there remain gaps in both respects. The article speculates on possible reasons for this and proposes reforms to improve courts’ approaches to sentencing offenders with ASD.
In the Public Interest: Protections and Risks in Whistleblowing to the Media
Authors: Ananian-Welsh Rebecca , Cronin Rose , Greste Peter
Published: December 2021

Whistleblowing and a free press are vital to facilitating public accountability for powerful institutions and thereby improving integrity across the public and private sectors. But when is a whistleblower permitted to disclose information to the media? Once a whistleblower speaks to a journalist, what protections and assurances will they be entitled to? This article addresses these questions by examining existing protections for private and public sector whistleblowers and, relatedly, journalists’ confidential sources under federal law. In this way, it explores the intersection between whistleblowing and press freedom and reveals gaps and weaknesses in existing legal frameworks.
A Better Model for Australia’s Enhanced Fintech Sandbox
Authors: Didenko Anton N
Published: December 2021

On 1 September 2020, Australia’s ‘enhanced regulatory sandbox’ (‘ERS’) finally became operational. The ERS replaced the previous FinTech sandbox established and operated by the Australian Securities and Investments Commission (‘ASIC’), which had existed since 2016 but attracted only seven participants. This research analyses how and why Australia’s sandbox framework – with its unique non-authorisation model of operation – has evolved until now and evaluates whether the new enhanced sandbox regime can help to achieve its stated objectives. This article shows that the current sandbox reform merely scrapes the surface of the many challenges underlying ASIC’s FinTech sandbox and argues that these challenges can only be adequately resolved by revising the chosen sandbox model and switching to an authorisation-based sandbox design.
A háború képe a Hadi és más nevezetes történetek, valamint a Magyar Hírmondó hasábjain a 18. század végén
Authors: Nagy-L. István
Published: December 2021

A tanulmány a korai magyar sajtótörténet fontos szereplőjével, a Hadi és más nevezetes történetek, átnevezését követően Magyar Hírmondó című hírlapjával foglalkozik. A klasszikus hírlapként működő újságot a török háború alatt alapította két kiváló, Bécsben élő magyar értelmiségi, Görög Demeter és Kerekes Sámuel. Mögöttük azonban ott állt a bécsi magyar kör több kiemelkedő felvilágosult reformer patrióta egyénisége, Széchényi Ferenc, Festetics György és Teleki Sámuel anyagi támogatása is. Az újság a magyar nemesi reformer csoport szócsöveként működött, témái között a kiemelt fontosságú katonai ügyeken túl politikai, gazdasági és irodalmi kérdések is megtalálhatók. A tanulmány a hírlap katonai híradásait veszi szemügyre és ezen keresztül a magyar „nemzeti ébredés” időszakának egyik fontos kérdését, a magyar vitézség szerepét mutatja be. A híradásokban fontos szerepet játszanak a levelek, amelyeket a harctérről írtak a szerkesztőségbe. A francia háború menetében bekövetkezett változások az újság tematikájában is szerkezeti átalakulást indítottak el. A harcok egyre közeledtek a magyar határhoz, így a háborús erőfeszítések mellett egyre inkább a honvédelem szerepe került előtérbe. Az újság a magyar nemzet haladásának, jólétének szolgálatában állt és működött fennállása egész idején.
Az Anapa melletti Andrejevszkaja scsel 10. századi leleteinek Kárpát-medencei párhuzamai
Authors: Novicsihin Andrej , Lezsák Gabriella , Gáll Erwin
Published: December 2021

A Kaukázus északi térségében egyre több olyan lelet kerül elő, amely technológiában, díszítésmódban és funkcióban a 10. századi, honfoglaláskori Kárpát-medence emlékanyagával mutat szoros kapcsolatokat. Az egyik ilyen leletcsoport az Anapa (Oroszország, Krasznodari határterület) melletti Andrejevszkaja scsel kora középkori temetőjéből származik. A leletek között szablyák, övdíszek, veretes és lemezes tarsolyok, palmettamintás, lemezes hajfonatkorong, valamint edények fordulnak elő. Jelen cikkben ezeket a tárgyakat elemezzük, azzal a céllal, hogy ismételten felhívjuk a figyelmet a korai magyarság története szempontjából fontos Észak-Kaukázus térségére. E szempontból jelzésértékűek azok a további szórványleletek is, amelyek az elmúlt években szintén Anapa környékén (pl. Buzsor, Gaikodzor, Leninszkij Puty, Skolnij stb.) kerültek elő, és ugyancsak a Kárpát-medencei, honfoglalás kori leletanyaggal állíthatók párhuzamba. A kutatás e kezdeti szakaszában nehéz egyértelmű választ adni arra, hogy ezek az észak-kaukázusi leletek kereskedelmi, katonai/politikai vagy kommunikációs, esetleg rokonsági hálózatok eredményének tekinthetők. Előrelépést csakis a további régészeti kutatások és az azzal párhuzamos interdiszciplináris vizsgálatok hozhatnak.
Preszkíta kori, szkíta kori lelőhelyek Heves megyében
Authors: Gutay Mónika , Bernáth László , Raáb Donát , Rácz Kristóf László
Published: December 2021

A Heves megyei preszkíta, szkíta kori lelőhelyek a Mátra-vidék, a Bükk-vidék, az Észak-alföldi-hordalékkúpsíkság és az Észak-magyarországi-medencék nevű középtájakon találhatók. Jelenleg a megyében 20 preszkíta és 26 szkíta kori lelőhely ismert. A preszkíta, Mezőcsáti-kultúra első leletei az 1933 és 1937 közötti füzesabonyi sírfeltárásokból kerültek elő. Az első szkíta kori sírleleteket pedig 1895-ben Hatvan-Vasút és 1908-ban Gyöngyös déli területéről ismertették. A Kárpát-medencében közel 2500 szkíta kori temetkezésből csupán 7-nek van körárka, közülük kettő Tarnabodon és Tarnamérán került elő. A legnagyobb szkíta kori temetők Eger-Nagy-Egeden, Hevesen és Gyöngyöshalász-Ocskay-laposon láttak napvilágot. Az elmúlt évtizedekben megnövekedett a szkíta kori lelőhelyek száma. A régészek elsősorban a nagyberuházásokhoz kapcsolódóan tártak fel szkíta kori lelőhelyeket. Aldebrő-Ilona-tábla lelőhelyen egy Kr. e. 772–490 közé keltezhető szkíta kori telepjelenséget és egy Kr. e. 775–488 közé tehető női halomsíros temetkezést tártunk fel. Gyöngyös-Külső-Mérges-patak 3. sz. lelőhely keleti részén szórványosabb szkíta kori telepet ástunk meg. Egy enyhén ovális alakú, 3,9x4,3 m-es, 13 cölöplyukból álló szkíta kori ház is előkerült. A temetkezésről és a házról 3D modellek, majd makettek készültek. Szentdomonkos-Szőke-tanyán későbronzkori, vaskori telepjelenségeket azonosítottunk. A geofizikai felmérés a lelőhely DNy-i részén szórványosabb, míg az É-i részen, egy nagy amplitúdójú pozitív anomáliát mutatott ki, amely jó eséllyel lehet egy fémművességhez köthető régészeti jelenség nyoma.
Química e arte: uma simbiose de matar
Authors: Andre Marcelo Fabiano , Quinhone Amanda , Marinho Maria Fernanda , Benedini Larissa Cristina Arruda de Oliveira
Published: December 2021

Desde a antiguidade o ser humano usa a tinta. No início era composta de base natural e orgânica, como o sangue, com o passar do tempo, sua composição ficou mais complexa e perigosa (resinas, pigmentos, diluentes, solventes e aditivos). Elementos como o chumbo e o mercúrio apesar de tóxicos estavam presentes, no entanto, não era comum o uso de equipamentos de proteção ao manusear as tintas o que gerava riscos a sua saúde física e mental, podendo levá-los à loucura e a morte. O objetivo deste trabalho é entender o efeito do chumbo no organismo e relacioná-lo com a morte dos pintores Vincent van Gogh e Cândido Portinari. Para compreender o assunto, foi realizada uma pesquisa bibliográfica qualitativa. Nela descobriu-se que o chumbo afeta principalmente o sistema nervoso, mesmo em baixas concentrações. A intoxicação nos pintores ocorria por meio das tintas por via oral e respiratória, principalmente pelo uso frequente das cores amarela, branco e azul (altas concentrações). Conclui-se que houve intoxicação por chumbo no caso Portinari e, no que tange à Van Gogh há controvérsias, mesmo demonstrando sinais de intoxicação.
Cultivation Prospective of Some Commercially Important Medicinal Plants for Indian Health System
Authors: Singh Charan , Alam N. , Dwivedi V.
Published: December 2021

Attempts have been made to provides comprehensive information on the distribution pattern, nativity, classification, cultivation practices and uses of some important medicinal plants of India. The distribution pattern of the species plays an important role for prioritization of the species for cultivation and conservation. It has been noted that cultivation of medicinal plants within the distribution range has received greater success than the cultivation of species outside the distribution range. India has rich diversity in medicinal plants, which needs to be exploited judiciously without disturbing its ecological balance. Undoubtedly, resources need to be harnessed for economic development but simultaneously we have to be concerned about their regeneration, preservation and propagation, so what these are available to us for use on a sustainable basis.
Bamboo Composite panel as furniture component using bamboo mat and planer shavings
Authors: Akhter Khurshid , Rahaman Md. , Chowdhury Mozammel , Islam Md.
Published: December 2021

Bamboo in panel form is well suited to wood substitute can be used as furniture components. During the preparation of strips by four side planer huge amount of wastage are obtained. In the present study, Planer shavings of Bhyjja, (Bambusa vulgaris) and Borak, (Bambusa balcooa) bamboo are used for manufacturing particleboard and mat overlaid particleboard. Mitinga, (Bambusa tulda) bamboo is used for making mat. Borax-boric acid (BB) treatments were given to enhance the durability of mat. The treatment were carried out using borax-boric acid (1:1) aqueous solution of different concentrations at different time schedule by soaking process.. Retention 22.11 kg/m3 to 27.41 kg/m3 were obtained when the mat were treated with 5% and 7% BB solution for 1 to 3 days. The modulus of rupture of bamboo particle board and mat overlaid particleboard were found 16 N/ mm2 and 25 N/ mm2respectively using planer shavings of Bambusa balcooa. The modulus of rupture of bamboo particle board and mat overlaid particleboard were found 18 N/ mm2 and 26.5 N/ mm2 respectively using planer shavings of Bambusa vulgaris. It was observed that the strength properties of board made form B. vulgaris higher than that of B. balcooa . Static bending /modulus of rupture of the particleboard are satisfactory. Modulus of rupture and tensile strengths of all the boards, however, satisfy the Indian and British standards. The strength properties of the mat overlaid particle board were increased due to the use of bamboo mat in the face and back position.
Pengalaman Mahasiswa Ilmu Keperawatan STIKES Cendekia Utama Kudus dalam Melaksanakan Pembelajaran Daring selama Masa Physical Distancing di Era Pandemi Covid-19
Authors: Indah Apriliana  , Gardha Rias Arsy  , Heriyanti Widyaningsih
Published: December 2021

Coronavirus Disease 19 (COVID-19) merupakan penyakit yang menular yang di sebabkan oleh Coronavirus atau Severe Acute Respiratory Syndrom Coronavirus 2 (Sars-Cov2) yang menyerang pada sistem pernafasan dan berkembang sangat cepat. Physical Distancing salah satu upaya pemerintah untuk menekan angka penyebaran dan resiko kematian akibat COVID-19. Physical Distancing juga diterapkan di STIKES Cendekia Utama Kudus pada prodi S1 Ilmu keperawatan dengan memberlakukan pembelajaran teori maupun praktik secara online atau daring. Penelitian ini dilakukan bertujuan untuk mengetahui pengalaman mahasiswa keperawatan tentang pembelajaran secara daring selama yaitu (1) Ragam pengalaman mahasiswa selama pembelajaran daring di masa pandemi Covid-19 (2) Hambatan mahasiswa selama pembelajaran daring di masa pandemi Covid-19 (3) Kelebihan selama pembelajaran daring di masa pandemi Covid-19 (4) Peningkatan pembelajaran daring selama masa pandemi Covid-19.
Efektivitas Terapi Bekam pada Penderita Hipertensi: Studi Literatur
Authors: Zahara Syifa Annisa  , Rudiyanto Rudiyanto , Sholihin Sholihin
Published: December 2021

Latar Belakang: : Hipertensi merupakan penyakit silent killer yang dapat terjadi tanpa gejala dan dapat menyebabkan komplikasi apabila tidak ditangani dengan cepat. Hipertensi dapat terjadi karena gaya hidup, obesitas, alkohol, merokok, stress, faktor usia, hingga faktor genetik. Pengobatan untuk hipertensi dapat dilakukan secara non-farmakologi yaitu dengan terapi bekam. Penelitian ini bertujuan mengetahui pengaruh terapi bekam pada penurunan tekanan darah pada penderita hipertensi.

Metode: : Pencarian Literature Review ini menggunakan analisis PICOT, dengan database Google Scholar, dan Garuda lalu dipilih artikel yang menggunakan metode quasy eksperimen serta artikel berbahasa indonesia dan bahasa inggris. Ditemukan 240 artikel, Selanjutnya di screening dan diambil artikel terbitan tahun 2015-2020 didapatkan 52 artikel. Berdasarkan jurnal akhir yang dianalisa sesuai kriteria inklusi dan ekslusi didapatkan 13 artikel. Kemudian di tinjau kembali berdasarkan artikel Nasional dan didapatkan hasil akhir 10 artikel yang ditelaah.

Hasil: Hasil literature review menunjukkan adanya pengaruh sebelum dan sesudah dilakukan terapi bekam. Hasil tekanan darah sebelum dilakukan terapi bekam berada dalam kategori hipertensi tingkat 1 (ringan) 60% dan hipertensi tingkat  2 (sedang) sebanyak 40%, setelah dilakukan terapi bekam berubah menjadi normal 20%, normal tinggi sebanyak 20%, dan hipertensi tingkat 1 (ringan) sebanyak 60% .

Kesimpulan: Pemberian terapi bekam sebagai salah satu terapi non-farmakologi mampu untuk diaplikasikan dalam menurunkan tekanan darah pada penderita hipertensi.
Augmented Reality (AR) Assisted Smart Glasses: Case Study for Remote Support Between Two Distant Production Plants
Authors: Caliskan Anil , Ozdemir Volkan
Published: December 2021

Rapid developments in technology enable us to reach smart glasses and AR technology with a wide range of products and competitive prices. Hence, increase in smart glasses industrial use give an opportunity to whom work distant such as making it possible to see from each other's eyes, which increases the operational efficiency of the companies; since it is costly to make experienced staff traveled to another plant in aspects of travel cost, accommodation cost and the lack of the experienced person in his/her the main responsibility area in factories with different experiences in remote locations. This study is conducted about the application of smart glasses on one of the biggest tire manufacturing company since 2018. End to end journey of the smart glasses' remote support applications, starting with how the devices are selected and ending with an evaluation of advantages/disadvantages of the smart glasses' technology, is explained in this paper. Moreover, the study covers details and observations of staff training, new product development, and inspections, first-run test on machinery, maintenance, and audits.
Spirulina Platensis and Bioremediation of Phosmet, Ethion, Methyl Parathion pesticides
Authors: Gul Ozlem , Bankoglu Yola Bahar , Kiran Tugba Raika , Yola Mehmet Lutfi
Published: December 2021

In this study, the bioremediation efficiency of some pesticides in Toxic Industrial Chemical category of CBRN (Chemical, Biological, Radioactive, Nuclear) threats with blue-green microalgae was investigated. Although these pesticides are highly harmful to human, living and environmental health, they are highly persistent in nature. Recently, the increasing demand and use of pesticides in the agricultural field poses risks in production, transportation and storage areas. The microalgae we have used are already known for its ability to metabolize pesticides, as well as its use in important areas, especially in the medicine and pharmaceutical industry. Using environmentally friendly bioremediation technique to eliminate or minimize the harmful effects of pesticides contributes to nature and the future. The fact that the selected microalgae and pesticides have not been investigated before proves the originality of our study. Pesticide remediation amount measurements were made by electrochemistry method and it was determined that Spirulina platensis removed Phosmet, Ethion and Methyl Paration by 70.0%, 61.0%, 50.0%, respectively, at the end of the 7th day.
Determining the relation between the count number and x-ray energy level in pyroelectric materials using linear regression analysis
Authors: Egeli Saadet Sena , Isler Yalcin
Published: December 2021

X-rays are a type of electromagnetic energy which widely used in different areas. Since their discovery, x-rays have been used, especially for medical imaging applications. On the other hand, new efficient x-ray generation methods have still been under investigation. Although new imaging modalities arose, xrays have never lost their popularity in many applications like computed tomography and dental imaging. Among these new methods, x-ray generation using pyroelectric crystal materials is one of the promising technologies. Pyroelectric crystals generate an electric field when a temperature change occurs and are affected by various parameters like how many times (count) the crystal’s temperature changed in a second. Hence, this new technology needs more research. In this study, we investigated the relationship between the count number and x-rays’ energy level of pyroelectric materials using linear regression analysis. We used a commercial software package, which is called the Statistical Package for the Social Sciences (SPSS), for this purpose. As a result, we achieved a good fit value of R2 = 0.91.
Devices Used by 112 Personnel in the Covid-19 Pandemic Process, Validation and Problems Encountered
Authors: Sanverdi Ahmet , Karagoz Eda Nur , Yola Mehmet Lutfi
Published: December 2021

The emergency health service is for all interventions that are made up of people who have received special education in their field, who work together in order to provide the best emergency response to the sick and injured in the shortest time possible in line with the possibilities available. In this context, although the emergency health service provided during the pandemic process requires the implementation of special procedures for healthcare professionals, it is important in the validation of the biomedical devices used during the provision of this service. Especially the fact that this process was a disaster that took place in an unexpected time period caused everyone to be caught unprepared and this situation caused the current workload of healthcare workers to increase even more. In this study, we conducted a literature search to shed light on the problems experienced by 112 emergency healthcare professionals during the pandemic period and how the validation of the biomedical devices used by these personnel in the ambulance should be. The type of research is descriptive research. The Covid-19 pandemic was accepted as a case and the literature was reviewed, with this case being the focus. During the literature search, up-to-date keywords such as "emergency health service, Covid-19, disaster preparedness, emergency aid unit employees, biomedical device technologies", which are also mentioned in the keywords, were scanned. Care was taken to ensure that the studies included in the review section were up to date and in accordance with the academic guide. In addition, due to the limitation of resources in the validation section of the research, assistance was received from the relevant legislation and expert medical company engineers and from the active staff in the field of healthcare professionals' problems. As a result of this research, we have reached the conclusion that legal regulations should be made regarding the problems experienced by healthcare professionals due to the pandemic and that existing standards related to device validation should be updated after the pandemic.
Forecasting Model to Predict the Spreading of the COVID-19 Outbreak in Turkey
Authors: Bereketoglu Ceyhun , Ozcan Nermin , Kiran Tugba Raika , Yola Mehmet Lutfi
Published: December 2021

This study aimed to forecast the future of the COVID-19 outbreak parameters such as spreading, case fatality, and case recovery values based on the publicly available epidemiological data for Turkey. We first performed different forecasting methods including Facebook's Prophet, ARIMA and Decision Tree. Based on the metrics of MAPE and MAE, Facebook's Prophet has the most effective forecasting model. Then, using Facebook's Prophet, we generated a forecast model for the evolution of the outbreak in Turkey fifteen-days-ahead. Based on the reported confirmed cases, the simulations suggest that the total number of infected people could reach 4328083 (with lower and upper bounds of 3854261 and 4888611, respectively) by April 23, 2021. Simulation forecast shows that death toll could reach 35656 with lower and upper bounds of 34806 and 36246, respectively. Besides, our findings suggest that although more than 86.38% growth in recovered cases might be possible, the future active cases will also significantly increase compared to the current active cases. This time series analysis indicates an increase trend of the COVID-19 outbreak in Turkey in the near future. Altogether, the present study highlights the importance of an efficient data-driven forecast model analysis for the simulation of the pandemic transmission and hence for further implementation of essential interventions for COVID-19 outbreak.
Pulse-Galvanic Skin Response Analysis with Multiple Sensor Device Design
Authors: Dincer Mehmet Ali , Evren Sahin Kubra , Sahin Savas
Published: December 2021

In this study, the development of a low-cost electronic card-based medical device measuring and recording patient data was described via non-invasive methods. Both the descriptive statistical analysis and the regression model was performed from the pulse and galvanic skin response (GSR) from the volunteer' data. It is important to measure and record different data simultaneously with multiple sensors from the patient during the treatment, medical operation and care periods of the patients. The data measured from the designed device was evaluated for the patient's position, GSR, the respiration rate, the blood oxygen content, and the heart rate. The designed measurement and recording device were implemented with an embedded system-based microcontroller card. The designed device might provide for monitoring and recording data with led display, serial port, microSD card or internet of things.
Manufacturing Multicolor LED-Based Phototherapy Device with a Novel 3D Design
Authors: Yasar Busra , Isler Yalcin , Topaloglu Avsar Nermin
Published: December 2021

Jaundice is a condition that results from an increase in bilirubin level in the blood. Its prevalence in newborns is around 60-70%. When this temporary jaundice becomes pathological and left untreated, significant damages may occur such as brain damage, vision loss, lung and kidney dysfunction, and even death. One of the methods used for the treatment of jaundice is phototherapy. In this study, a design has been made with 3 foldable LED panels to increase the target area. In addition, high-voltage LEDs with blue-green white wavelengths were used. Thus, it was aimed to minimize the risks of nausea and dizziness caused by intense blue light. An automatic system has been achieved by using temperature and light intensity sensors. The system will warn the user at temperatures and light intensity that are harmful to the baby.
THE WEALTH EFFECT IN AGRICULTURE IN LIGHT OF EXPERIENCES OF FARMS FROM THE WIELKOPOLSKA REGION
Authors: Grzelak Aleksander
Published: December 2021

The aim of the article is to initially identify the characteristics of farms in which the wealth effect appears and recognize the extent of this effect in market farms in the Wielkopolska Region. This was realized based on the results of 120 questionnaire surveys of farms in the Wielkopolska Region. The research shows that there is a group of farms in which the wealth effect takes place (9.2% in the surveyed group). This mainly applies to units specializing in field crops. Farms in which the potential wealth effect appears are characterized by a larger area of arable land but, on the other hand, by a lower income, value of assets and output. In addition to the risks associated with this effect, there are also positive aspects relating to an increased economic activity of farms or an increase in the possibility of credit guarantees. In the context of research results, it would be advisable, in the future, to increase the degressivity of area payments under the CAP due to their lower impact of payments on the capitalization of subsidies and, thus, the intrinsic increase in asset value in farms.