bluuebunny/crossref_metadata_2025 huggingface dataset:
Lingual articulatory configurations of Japanese devoiced vowels
Authors: Iwasaki Rion , Whalen D. H. , Roon Kevin , Shaw Jason A.
Published: November 2019

High vowels in Tokyo Japanese are typically devoiced between voiceless obstruents, but there is controversy about whether they can also be deleted entirely or not. Deciding this issue is important because vowel deletion would have implications for Japanese phonology and phonotactics such as consonant clusters in word-initial position and their syllabification. Here, we use ultrasound to examine whether devoiced vowels have the same tongue configurations as those of their voiced counterparts (i.e., they are simply unphonated) or not (i.e., they are deleted). For comparison, this study also examines whispered speech. The whispered vowels are assumed to be unphonated and presumably have the same tongue configurations as the voiced vowels. Native speakers of Tokyo Japanese produced word pairs contrasting in the voicing realization of a high vowel. The comparison between devoiced, voiced, and whispered vowels was made by quantifying differences in the tongue contour traced from respective ultrasound frames. Several consonantal conditions of devoicing were considered. Preliminary results indicate that devoiced vowels might have different tongue configurations from those of voiced and whispered vowels in certain consonantal conditions.
Automatic classification of French stops consonants
Authors: Ponchard Clara , Demolin Didier , Hassid Sergio
Published: November 2019

The purpose of this study is to analyze aerodynamic parameters involved in the production of French stops consonants. We are focusing our analysis on intraoral and subglottic pressure measurements. The main goal of this study is to automate the processing of aerodynamic data measurements in order to contribute to provide reference data that are still limited in the literature. We are also analyzing pressure variations according to the voicing opposition, the intervocalic context, and different places of articulation. Phonetic analysis is carried out by means of statistical tests in order to analyze the descriptors considered relevant to understand the consonants’ variations. Then, a supervised classification task to assess the relevance of these descriptors is made. Phonetic, automatic language processing and machine learning methods are processed in this work.
Big League Social Media: Cultivating Community Online
Authors: Weingartz Ashley N. , Warner Stacy
Published: November 2019

This case addresses a timely problem many non-profit sport organizations face: social media management. Due to a lack of resources and technical skills, many organizations fail to effectively utilize social media. This case focuses on the challenges of social media integration in Greenville Little Leagues (GLL), a chartered member of Little League International. Little League International is a global non-profit sports organization comprised of local league members such as GLL. This case focuses on a dilemma an intern with GLL must solve regarding social media and its annual tournament. The case outlines the organizational details regarding GLL’s operation and annual tournament, as well as their current social media strategy. This case provides an opportunity for students to: 1) examine effective tactics for using social media to develop community, 2) develop strategies non-profit sport organizations could use to promote community building, 3) identify cost-effective social media tactics for engaging a rapidly changing audience, and 4) articulate how to effectively utilize volunteers to share social media responsibilities. The case is intended for use in event management, organizational behavior, and/or marketing courses and provides an opportunity to highlight how research can and should inform practice.
The Host GTPase Arf1 and Its Effectors AP1 and PICK1 Stimulate Actin Polymerization and Exocytosis To Promote Entry of Listeria monocytogenes
Authors: Saila Susan , Gyanwali Gaurav Chandra , Hussain Mazhar , Gianfelice Antonella , Ireton Keith
Published: November 2019

Listeria monocytogenes
is a foodborne bacterium that causes gastroenteritis, meningitis, or abortion.
Listeria
induces its internalization (entry) into some human cells through interaction of the bacterial surface protein InlB with its host receptor, the Met tyrosine kinase. InlB and Met promote entry through stimulation of localized actin polymerization and exocytosis. How actin cytoskeletal changes and exocytosis are controlled during entry is not well understood.
Posttranslational Methylation of Arginine in Methyl Coenzyme M Reductase Has a Profound Impact on both Methanogenesis and Growth of Methanococcus maripaludis
Authors: Lyu Zhe , Shao Nana , Chou Chau-Wen , Shi Hao , Patel Ricky , Duin Evert C. , Whitman William B.
Published: November 2019

Mcr is the key enzyme in methanogenesis and a promising candidate for bioengineering the conversion of methane to liquid fuel. Our knowledge of Mcr is still limited. In terms of complexity, uniqueness, and environmental importance, Mcr is more comparable to photosynthetic reaction centers than conventional enzymes. PTMs have long been hypothesized to play key roles in modulating Mcr activity. Here, we directly link the
mmpX
gene to the arginine PTM of Mcr, demonstrate its association with methanogenesis activity, and offer insights into its substrate specificity and putative cofactor binding sites. This is also the first time that a PTM of McrA has been shown to have a substantial impact on both methanogenesis and growth in the absence of additional stressors.
Building a Better Test for Piperacillin-Tazobactam Susceptibility Testing: Would that It Were So Simple (It's Complicated)
Authors: Henderson Andrew , Humphries Romney
Published: November 2019

In this issue of the
Journal of Clinical Microbiology
, S. García-Fernandez, Y. Bala, T. Armstrong, M. Garcia-Castillo, et al. (J Clin Microbiol 58:e01042-19, 2020,
https://doi.org/10.1128/JCM.01042-19
) describe the performance of a reformulated Etest for piperacillin-tazobactam.
Photodynamic therapy-induced acute exudative maculopathy in a case of choroidal haemangioma
Authors: Chakurkar Renuka , Tyagi Mudit , Pappuru Rajeev Reddy , Kaliki Swathi
Published: November 2019

A patient with choroidal haemangioma in the right eye developed photodynamic therapy (PDT)-induced acute exudative maculopathy within a week of being subjected to PDT (for treating the choroidal haemangioma). The condition was managed with an intravitreal injection of bevacizumab and responded well to therapy.
Neighbourhood greenspace and physical activity and sedentary behaviour among older adults with a recent diagnosis of type 2 diabetes: a prospective analysis
Authors: Chong Shanley , Mazumdar Soumya , Ding Ding , Morgan Geoff , Comino Elizabeth Jean , Bauman Adrian , Jalaludin Bin
Published: November 2019

Objectives

Greenspace is one of the important factors that can promote an active lifestyle. Thus, greener surroundings may be a motivating factor for people with newly diagnosed diabetes to engage in more physical activity. Given that diagnosis of type 2 diabetes (T2D) may serve as a window opportunity for behavioural modification, we hypothesise that the association between neighbourhood greenspace and physical activity among people with newly diagnosed T2D may be greater than those not diagnosed with T2D. The aim of this study was to investigate the association between access to greenspace and changes in physical activity and sedentary behaviour, and whether these associations differed by T2D.

Design

Prospective cohort.

Setting

New South Wales, Australia.

Methods

We used self-reported information from the New South Wales 45 and Up Study (baseline) and a follow-up study. Information on sitting, walking and moderate to vigorous physical activity was used as outcomes. The proportion of greenspace within 500 m, 1 km and 2 km road network buffers around participant’s residential address was generated as a proxy measure for access to greenspace. The association between the access to greenspace and the outcomes were explored among the newly diagnosed T2D group and those without T2D.

Results

Among New T2D, although no significant changes were found in the amount of walking with the percentage of greenspace, increasing trends were apparent. There was no significant association between the percentage of greenspace and changes in amount of moderate to vigorous physical activity (MVPA). Among No T2D, there were no significant associations between the amount of MVPA and walking, and percentage of greenspace. For changes in sitting time, there were no significant associations with percentage of greenspace regardless of buffer size.

Conclusions

In this study, there was no association between access to greenspace at baseline and change in walking, MVPA and sitting time, regardless of T2D status.
Cohort profile: the Danish Work Life Course Cohort study (DaWCo)
Authors: Svane-Petersen Annemette Coop , Framke Elisabeth , Sørensen Jeppe Karl , Rugulies Reiner , Madsen Ida Elisabeth Huitfeldt
Published: November 2019

Purpose

The Danish Work Life Course Cohort (DaWCo) was initiated to study relations between working conditions, health and labour market affiliation using repeated measures of these factors throughout the working life, while accounting for health-differences pre-existing labour market entry.

Participants

The cohort encompasses all 15–30-year-old individuals residing in Denmark who entered the labour market during the years 1995–2009 (960 562 individuals and 7 136 188 observations). Data include information on working conditions measured by job exposure matrices linked with registers on health, labour market affiliation and sociodemographics for both the cohort members and their parents. The median age at cohort entry was 20 years and men and women were equally represented.

Findings to date

Currently, one study has been published, which found that low job control was associated with increased risk of depressive disorder, independently from indicators of socioeconomic position measured throughout the life-course. The present cohort profile presents data regarding the transitions of cohort members between states of labour market affiliation and data on health services use. All cohort members were employed in their year of entry, but this proportion decreased across the years to 82.4% in the 10th year since cohort entry. The proportion of students peaked at 5 years since cohort entry with 13.9%.

Future plans

This large prospective cohort offers the possibility to study associations between psychosocial working conditions and rare outcomes and to examine the potential accumulation of effects while accounting for health-differences pre-existing labour market entry. Currently, we are working on analyses on risk of hospital-diagnosed incident depression and disability pensioning. The study is ongoing, and we are planning to extend the study to include the years 2010–2018 and expand the cohort with individuals entering the Danish workforce during these years.
Participating in core outcome set development via Delphi surveys: qualitative interviews provide pointers to inform guidance
Authors: Biggane Alice M , Williamson Paula R , Ravaud Philippe , Young Bridget
Published: November 2019

Objectives

To explore participants’ views of Delphi surveys in core outcome set (COS) development.

Study design and setting

Patients and health professionals (n=24) from seven recently concluded COS studies that had involved a Delphi survey took part in semistructured qualitative interviews (telephone and email exchange). Interviews explored participants’ understanding of COS and their experiences of the Delphi survey. Analysis was thematic.

Results

Several interviewees had previously participated in two or more COS or Delphi surveys. Those with multiple experiences of participation generally understood the purpose of COS and were satisfied with the Delphi survey. However, some interviewees who were first-time participants struggled to understand the purpose of COS and aspects of the Delphi survey, which limited their contribution and satisfaction with the study. Interviewees also differed in how they interpreted and subsequently used the written documentation provided to COS participants. Some interviewees wanted guidance regarding whose perspective to take into account when scoring outcomes and on how to use the scoring system. Interviewees reported being motivated to take part by the international and expert consensus aspects of the Delphi survey. A few interviewees reported experiencing either positive or negative emotional impacts arising from when they reviewed outcomes and stakeholder feedback.

Conclusion

This study identifies important information that should be communicated to COS Delphi study participants. It also indicates the importance of communicating about COS Delphi studies in ways that are accessible and salient to participants, to enhance their experience of participation and make the process more meaningful for all.
Cohort profile: the Health of Philippine Emigrants Study (HoPES) to examine the health impacts of international migration from the Philippines to the USA
Authors: de Castro A B , Hing Anna K , Lee Nanette R , Kabamalan Maria Midea M , Llave Karen , Crespi Catherine M , Wang May , Gee Gilbert
Published: November 2019

Purpose

The Health of Philippine Emigrants Study (HoPES) longitudinally investigates over 3 years whether migrating from the Philippines to the USA results in increased risk for obesity relative to non-migrants in the Philippines. The study is designed to test the healthy immigrant hypothesis by collecting health measures from migrants starting from a pre-migration baseline and enrolling a non-migrant cohort matched on age, gender and education for comparison.

Participants

A migrant cohort (n=832; 36.5% of eligible individuals) was recruited from clients of the Commission on Filipinos Overseas prior to exiting the Philippines. A non-migrant cohort (n=805; 68.6% eligible individuals) was recruited from community households in municipalities throughout the cities of Manila and Cebu. By intention, these two cohorts are comparable demographically, including urban/rural status of residency in the Philippines at baseline.

Findings to date

At baseline, compared with non-migrants, migrants report significantly better self-rated health and less depression, and have significantly larger hip circumference and lower waist-to-hip ratio, as well as significantly higher mean systolic blood pressure and higher mean level of apolipoprotein B. Baseline results can offer insight into the health status of both migrant and non-migrant populations and may be useful for obesity prevention efforts.

Future plans

Longitudinal data collection is scheduled to be completed in December 2020 when the final data collection wave (36 months after baseline) will conclude. Both migrant and non-migrant cohorts will be maintained beyond the current prospective study, so long as research funding allows and emerges for new study questions. Findings from future longitudinal analyses can inform the need and design of health-related/relevant interventions, whether clinical, behavioural, educational, or policy, that can be implemented at the individual or population level.
Premedication practices for tracheal intubation in neonates transported by French medical transport teams: a prospective observational study
Authors: Carbajal Ricardo , Lode Noella , Ayachi Azzedine , Chouakri Ourida , Henry-Larzul Véronique , Kessous Katia , Normand Audrey , Courtois Emilie , Rousseau Jessica , Cimerman Patricia , Chabernaud Jean-Louis
Published: November 2019

Objectives

Premedication practices for neonatal tracheal intubations have not yet been described for neonatal transport teams. Our objective is to describe the use of sedation/analgesia (SA) for tracheal intubations and to assess its tolerance in neonates transported by medical transport teams in France.

Setting

This prospective observational study was part of the EPIPPAIN 2 project and collected around-the-clock data on SA practices in neonates intubated by all five paediatric medical transport teams of the Paris region during a 2-month period. Intubations were classified as emergent, semiemergent and non-emergent. Sedation level and conditions of intubation were assessed with the Tonus, Reactivity, Awareness and Conditions of intubation to Help in Endotracheal intubation Assessment (TRACHEA score). The scores range from 0 to 10 representing an increasing ladder from adequate to inadequate sedation, and from excellent to very poor conditions of intubation.

Participants

40 neonates intubated in 28 different centres.

Results

The mean (SD) age was 34.9 (3.9) weeks, and 62.5% were intubated in the delivery room. 30/40 (75%) of intubations were performed with the use of SA. In 18/30 (60.0%) intubations performed with SA, the drug regimen was the association of sufentanil and midazolam. Atropine was given in 19/40 intubations. From the 16, 21 and 3 intubations classified as emergent, semiemergent and non-emergent, respectively, 8 (50%), 19 (90.5%) and 3 (100%) were performed with SA premedication. 79.3% of intubations performed with SA had TRACHEA scores of 3 or less. 22/40 (55%) infants had at least one of the following adverse events: muscle rigidity, bradycardia below 100/min, desaturation below 80% and nose or pharynx–larynx bleeding. 7/24 (29.2%) of those who had only one attempt presented at least one of these adverse events compared with 15/16 (93.8%) of those who needed two or more attempts (p<0.001).

Conclusion

SA premedication is largely feasible for tracheal intubations performed in neonates transported by medical transport teams including intubations judged as emergent or semiemergent.

Trial registration number

NCT01346813; Results.
Biathlon Injury and Illness Surveillance project (BIIS): development of biathlon-specific surveillance forms in English, Russian, French and German
Authors: Van Dyk Carlee , Panagodage Perera Nirmala , Carrabre James E , Manfredini Fabio , Fitzpatrick Jane
Published: November 2019

Objective

The aim of this project was to adapt the English, French, German and Russian versions of the International Olympic Committee (IOC)injury and illness surveillance formto be sport-specific for use in biathlon.

Methods

23 medical representatives from 16 of the 55 biathlon federations participated in this project to adapt the form and create disease coding relevant to biathlon. The English version of theIOC injury and illness surveillance formwas used as the primary template. Four review rounds were used to develop electronic fillable PDF forms. The changes were then forward translated onto the Russian, French and German forms.

Results

Changes were made to event type to biathlon-specific events. A weekly reporting format was adopted in line with the race week format of World Cup events. Wherever possible, coding replaced free-text format to avoid translation issues. New codes were created to describe the time of injury/illness. A new symptom code was added to reflect the prevalence of respiratory infection: sore throat/cold symptoms. As the number of athletes in a team differs between weeks in the season, an additional question was added to ask for the ‘number of athletes in the team for the week’ and for the season.

Conclusion

This project provides a biathlon-specific injury and illness surveillance form in English, French, German and Russian. This forms the basis for surveillance that will contribute to a greater understanding of the illness and injury rate in elite biathletes and ultimately to enhanced athlete well-being and success in biathlon, and winter sports more generally.
Suicide among persons who entered same-sex and opposite-sex marriage in Denmark and Sweden, 1989–2016: a binational, register-based cohort study
Authors: Erlangsen Annette , Drefahl Sven , Haas Ann , Bjorkenstam Charlotte , Nordentoft Merete , Andersson Gunnar
Published: November 2019

Background

People belonging to sexual minority groups have higher levels of suicidality than heterosexuals. However, findings regarding suicide death are sparse. Using unique national data from two countries, we investigated whether individuals entering a same-sex marriage (SSM), a proxy group of sexual minority individuals, had higher suicide rates than those entering opposite-sex marriage (OSM).

Methods

A cohort study of all males and females who entered an SSM (n=28 649) or OSM (n=3 918 617) in Denmark and Sweden during 1989–2016 was conducted. Incidence rate ratios (IRRs) for suicide were calculated using adjusted Poisson regression models.

Results

In total, 97 suicides occurred among individuals who had entered an SSM compared with 6074 among those who entered an OSM, corresponding to an adjusted IRR of 2.3 (95% CI 1.9 to 2.8). For people who entered SSM, a 46% decline was noted over time from an IRR of 2.8 (95% CI 1.9 to 4.0) during 1989–2002 to 1.5 (95% CI 1.2 to 1.9) during 2003–2016. The excess suicide mortality was present in all age groups but most pronounced among younger individuals aged 18–34 years of age (IRR 2.7, 95% CI 1.5 to 4.8) and females (IRR 2.7, 95% CI 1.8 to 3.9).

Conclusion

This large register-based study found higher suicide rates among individuals who entered an SSM, compared with those who entered an OSM. A lower suicide rate was noted for individuals in SSMs in recent years. More research is needed to identify the unique suicide risk and protective factors for sexual minority people.
Galloping response of sector-shape iced eight bundle conductors
Authors: Cai Meng-qi , Zhou Lin-shu , Xu Qian , Yang Xiao-hui , Liu Xiao-hui
Published: November 2019

Wind tunnel test results of the aerodynamic coefficients of sector-shape iced eight bundle conductors varying with wind attack angles are presented. Then, by means of the user-defined cable elements, the aerodynamic loads are applied on the cable elements of each sub-conductor through the finite element method (FEM). In addition, the galloping responses of sector-shape iced eight bundle conductors are discussed. Finally, galloping responses, including dynamic responses (natural modes and frequencies), galloping orbits, and amplitudes of typical sector-shape iced eight bundle conductor transmission lines in the cases of different span lengths, wind velocities, and angles of wind attack are studied, respectively. These results provide useful references for a theoretical basis for the study of galloping and the technique of anti-galloping in cold regions.
Multidecadal shifts in forest plant diversity and community composition across glacial landforms in northern lower Michigan, USA
Authors: Ricart Raleigh D. , Pearsall Douglas R. , Curtis Peter S.
Published: November 2019

Understanding how plant community assemblage is affected by spatial and temporal patterns is crucial to understanding forest ecosystem responses to disturbance, including future climate change. In this article, we tracked how diversity and composition are distributed through space and time in a midsuccessional mixed hardwood forest in northern lower Michigan, United States. This region’s geographically and abiotically distinct glacial landforms influence both the spatial and temporal dynamics of its forest communities. Vegetation sampling plots (n = 87) were established at the University of Michigan Biological Station in 1990 and resampled in 2015. Vegetation in the overstory, sapling, and groundcover layers was censused. Abiotic variables, including elevation, pH, and soil nutrients, were measured in a subset of plots (n = 40). There were strong differences in diversity and community composition among glacial landforms, with the moraine having a 31% greater species richness in the groundcover layer compared with those of the other glacial landforms. Surprisingly, plant communities across all three vegetation layers showed little change over the 25-year period, and we found no evidence of differences in successional rates among glacial landforms. Our findings indicate that glacial landforms have a large influence on the production and maintenance of local plant diversity and community composition in this area and suggest that successional dynamics may manifest themselves over much longer time periods in these northern biomes.
The Finslerian quantum cosmology
Authors: De S.S. , Rahaman Farook , Paul Nupur
Published: November 2019

We present a Friedmann–Robertson–Walker quantum cosmological model within the framework of Finslerian geometry. In this work, we consider a specific fluid. We obtain the corresponding Wheeler–DeWitt equation as the usual constraint equation as well as the Schrödinger equation following Dirac, although the approaches yield the same time-independent equation for the wave function of the universe. We provide exact classical and quantum mechanical solutions. We use eigenfunctions to study the time evolution of the expectation value of the scale factor. Finally, we discuss the physical meaning of the results.
From individual to collective behaviours: exploring population heterogeneity of human mobility based on social media data
Authors: Liao Yuan , Yeh Sonia , Jeuken Gustavo S.
Published: November 2019

This paper examines the population heterogeneity of travel behaviours from a combined perspective of individual actors and collective behaviours. We use a social media dataset of 652,945 geotagged tweets generated by 2,933 Swedish Twitter users covering an average time span of 3.6 years. No explicit geographical boundaries, such as national borders or administrative boundaries, are applied to the data. We use spatial features, such as geographical characteristics and network properties, and apply a clustering technique to reveal the heterogeneity of geotagged activity patterns. We find four distinct groups of travellers: local explorers (78.0%), local returners (14.4%), global explorers (7.3%), and global returners (0.3%). These groups exhibit distinct mobility characteristics, such as trip distance, diffusion process, percentage of domestic trips, visiting frequency of the most-visited locations, and total number of geotagged locations. Geotagged social media data are gradually being incorporated into travel behaviour studies as user-contributed data sources. While such data have many advantages, including easy access and the flexibility to capture movements across multiple scales (individual, city, country, and globe), more attention is still needed on data validation and identifying potential biases associated with these data. We validate against the data from a household travel survey and find that despite good agreement of trip distances (one-day and long-distance trips), we also find some differences in home location and the frequency of international trips, possibly due to population bias and behaviour distortion in Twitter data. Future work includes identifying and removing additional biases so that results from geotagged activity patterns may be generalised to human mobility patterns. This study explores the heterogeneity of behavioural groups and their spatial mobility including travel and day-to-day displacement. The findings of this paper could be relevant for disease prediction, transport modelling, and the broader social sciences.
On the wave turbulence theory for stratified flows in the ocean
Authors: Gamba Irene M. , Smith Leslie M. , Tran Minh-Binh
Published: November 2019

After the pioneering work of Garrett and Munk, the statistics of oceanic internal gravity waves has become a central subject of research in oceanography. The time evolution of the spectral energy of internal waves in the ocean can be described by a near-resonance wave turbulence equation, of quantum Boltzmann type. In this work, we provide the first rigorous mathematical study for the equation by showing the global existence and uniqueness of strong solutions.
Rotational behavior of thermally excited 56Fe, 58Fe and 60Fe isotopes
Authors: Muhila Suba Janani A. , Boomadevi N. , Rajasekaran T. R.
Published: November 2019

Thermal and rotational behaviors of neutron rich fp-shell isotopes such as [Formula: see text], [Formula: see text] and [Formula: see text] were analyzed microscopically within the framework of statistical theory of hot rotating nuclei (STHRN) for the angular momentum range (0–15)[Formula: see text] at excitation energy above 4[Formula: see text]MeV. Pair-breaking phenomenon and band-crossing phenomenon of Fe isotopes were discussed with and without the inclusion of BCS pairing. The STHRN method with BCS effect was extended to the Fe isotopes to determine the critical temperature [Formula: see text], where the pair-breaking phenomenon takes place and it is found to occur below [Formula: see text][Formula: see text]MeV. The observation of band-crossing phenomenon above the [Formula: see text] was explained without considering the effect of BCS pairing. The single particle energy levels were engendered from triaxially deformed Nilsson Hamiltonian. The outcomes of the present investigation on moment of inertia (MOI), back-bending phenomenon, spin cutoff parameter show a strong evidence of band-crossing phenomenon and it eventually led to a shape transition from spherical to noncollective oblate. Moreover, attention on separation energy of protons and neutrons reveals that the neutron pairs are responsible for band-crossing. STHRN method was able to reproduce results in good agreement with experiments and comparable with other theories such as projected shellmodel (PSM) and shellmodel Monte Carlo (SMMC) method.
Some algebraic algebras with Engel unit groups
Authors: Bien M. H. , Ramezan-Nassab M.
Published: November 2019

In this paper, we study some algebras [Formula: see text] whose unit groups [Formula: see text] or subnormal subgroups of [Formula: see text] are (generalized) Engel. For example, we show that any generalized Engel subnormal subgroup of the multiplicative group of division rings with uncountable centers is central. Some of algebraic structures of Engel subnormal subgroups of the unit groups of skew group algebras over locally finite or torsion groups are also investigated.
Some splitting theorems for local cohomology modules with respect to a pair of ideals
Authors: Naal Batoul , Khashyarmanesh Kazem
Published: November 2019

Suppose that [Formula: see text] is a commutative ring with identity, [Formula: see text], [Formula: see text] are ideals of [Formula: see text], and let [Formula: see text] be a finitely generated [Formula: see text]-module. Let [Formula: see text] be the [Formula: see text]th local cohomology functor with respect to [Formula: see text]. In this paper, for fixed integers [Formula: see text] and [Formula: see text], we study the existence of the following isomorphisms of local cohomology modules:

(i) [Formula: see text]; (ii) [Formula: see text]; and, (iii) [Formula: see text]

for some filter regular element [Formula: see text] on [Formula: see text]. Moreover, we provide some applications of the above isomorphisms.
A study on Hermite–Hadamard-type inequalities via new fractional conformable integrals
Authors: Set Erhan , Gözpinar Abdurrahman , Butt Saad Ihsan
Published: November 2019

Due to their wide range of applications in many areas of modern analysis, the splendid Hermite–Hadamard inequalities for convex function are very attractive for researcher community. Many authors have been working on their variants, refinements and extensions. The aim of this research is to establish a novel identity and Hermite–Hadamard-type inequalities for convex functions linked with the renowned conformable integral operators. We have pointed some particular cases of the results obtained here in order to show that they reduce some well-known results to relatively simple ones.
Analysis of porosity influence on the effective moduli of ceramic matrix PZT composite using the simplified finite element model
Authors: Kudimova Anna , Nasedkin Andrey
Published: November 2019

The problem of determining the effective moduli of a ceramic matrix piezocomposite with respect to multiscale porosity was considered. To solve the homogenization problem, the method of effective moduli in the standard formulation, the finite element method and the ANSYS computational package were used. Various models of two-phase and three-phase composites consisting of a piezoceramic matrix, elastic inclusions of corundum and pores of various sizes have been investigated. Finite element models of representative volumes of 3–0 and 3–0–0 connectivities were developed. The results of computational experiments showed that effective moduli depend quite significantly not only on the volume fractions of inclusions and pores, but also on the structure and size of pores in comparison with the characteristic sizes of inclusions.
Augmented Reality Training Platform for Neurosurgical Burr Hole Localization
Authors: Baum Zachary M. C. , Lasso Andras , Ryan Sarah , Ungi Tamas , Rae Emily , Zevin Boris , Levy Ron , Fichtinger Gabor
Published: November 2019

Augmented reality (AR) is used in neurosurgery to visualize lesions and plan procedures pre-operatively and intra-operatively, though its use has not been widely adopted in simulation-based neurosurgical training for the same tasks. This work defines metrics to determine performance in drill position and angle identification for neurosurgical training. The metrics were validated intra-operatively and in a simulated training environment, demonstrating that trainees identify drill position and angle faster and more accurately with AR compared with standard techniques. Training using AR and the proposed metrics stands to add value to neurosurgical curricula development.
A Survey of Intrusion Detection Systems Leveraging Host Data
Authors: Bridges Robert A. , Glass-Vanderlan Tarrah R. , Iannacone Michael D. , Vincent Maria S. , Chen Qian (Guenevere)
Published: November 2019

This survey focuses on intrusion detection systems (IDS) that leverage host-based data sources for detecting attacks on enterprise network. The host-based IDS (HIDS) literature is organized by the input data source, presenting targeted sub-surveys of HIDS research leveraging system logs, audit data, Windows Registry, file systems, and program analysis. While system calls are generally included in audit data, several publicly available system call datasets have spawned a flurry of IDS research on this topic, which merits a separate section. To accommodate current researchers, a section giving descriptions of publicly available datasets is included, outlining their characteristics and shortcomings when used for IDS evaluation. Related surveys are organized and described. All sections are accompanied by tables concisely organizing the literature and datasets discussed. Finally, challenges, trends, and broader observations are throughout the survey and in the conclusion along with future directions of IDS research. Overall, this survey was designed to allow easy access to the diverse types of data available on a host for sensing intrusion, the progressions of research using each, and the accessible datasets for prototyping in the area.
SEGarage
Authors: Arumugam Lakshmanan , Subramanian Vikram N. , Nagappan Meiyappan
Published: November 2019

SEGarage is a curated archive for software engineering tools developed through software engineering research. This service aims to ease the effort of finding and downloading tools from past research.
Risks to the Public
Authors: Neumann Peter G.
Published: November 2019

Discussion of the two 737 Max fatal losses has persisted (noted in R 31 11 to R 31 27), and is still ongoing. The desired use of lighter engines altered the nose-lift behavior, and resulted in an automated system that attempted to compensate for the changes; shortsighted use of only one of two sensors was implicated in both losses, along with issues surrounding pilot training to override the controls, ongoing plans to revise the software, regulatory difficulties (with self-assessment of the risks), shortcomings of ight simulators, and other issues. As I review this on 2 June, a NYTimes article today summarized \The Late Change, and Fatal Flaws".
Time-dependent regulation of postprandial muscle protein synthesis rates after milk protein ingestion in young men
Authors: van Vliet Stephan , Beals Joseph W. , Holwerda Andrew M. , Emmons Russell S. , Goessens Joy P. , Paluska Scott A. , De Lisio Michael , van Loon Luc J. C. , Burd Nicholas A.
Published: November 2019

The anabolic action of “fast” whey protein on the regulation of postprandial muscle protein synthesis has been established to be short-lived in healthy young adults. We assessed the time course of anabolic signaling activation and stimulation of myofibrillar protein synthesis rates (MPS) after ingestion of a food source that represents a more typical meal-induced pattern of aminoacidemia. Seven young men (age: 22 ± 1 y) underwent repeated blood and biopsy sampling during primed, continuous l-[ ring-2H5]phenylalanine and l-[1-13C]leucine tracer infusions and ingested 38 g of l-[1-13C]phenylalanine- and l-[1-13C]leucine-labeled milk protein concentrate. A total of ∼27 ± 4 (∼10 g) and ∼31 ± 1% (∼12 g) of dietary protein-derived amino acids were released in circulation between 0 and 120 min and 120–300 min, respectively, of the postprandial period. l-[ ring-2H5]phenylalanine-based MPS increased above basal (0.025 ± 0.008%/h) by ∼75% (0.043 ± 0.009%/h; P = 0.05) between 0 and 120 min and by ∼86% (0.046 ± 0.004%/h; P = 0.02) between 120 and 300 min, respectively. l-[1-13C]leucine-based MPS increased above basal (0.027 ± 0.002%/h) by ∼72% (0.051 ± 0.016%/h; P = 0.10) between 0 and 120 min and by ∼62% (0.047 ± 0.004%/h; P = 0.001) between 120 and 300 min, respectively. Myofibrillar protein-bound l-[1-13C]phenylalanine increased over time ( P < 0.001) and equaled 0.004 ± 0.001, 0.008 ± 0.002, 0.017 ± 0.004, and 0.020 ± 0.003 mole percent excess at 60, 120, 180, and 300 min, respectively, of the postprandial period. Milk protein ingestion increased mTORC1 phosphorylation at 120, 180, and 300 min of the postprandial period (all P < 0.05). Our results show that ingestion of 38 g of milk protein results in sustained increases in MPS throughout a 5-h postprandial period in healthy young men.

NEW & NOTEWORTHY The stimulation of muscle protein synthesis after whey protein ingestion is short-lived due to its transient systemic appearance of amino acids. Our study characterized the muscle anabolic response to a protein source that results in a more gradual release of amino acids into circulation. Our work demonstrates that a sustained increase in postprandial plasma amino acid availability after milk protein ingestion results in a prolonged stimulation of muscle protein synthesis rates in healthy young men.
Brittleness Risk Evaluation of Mine Safety Based on Brittle Relational Entropy
Authors: Xiang Chenglang , Zhou En , Hong Rui , Liu Hui , Xu Xiaomeng
Published: November 2019

Mineral extracting involves lots of uncertain factors which take on the typically nonlinear characteristics. To find out the accidents caused by main factors and make clear of disaster‐causing factors and risk sources, a modified risk evaluation model‐associated interaction effect analysis method was constructed from four aspects of man subsystem, machine subsystem, working environment subsystem, and operations management subsystem. With this model, the theory of brittleness relation was applied to analyze closely the connection between mine safety and various subsystems and their interaction effects on mine safety. Furthermore, brittleness factors were also proposed according to the characteristics of underground mining. Finally, based on data from working fields and investigation results, taking a typical mine as an example, the analysis was carried out. The results show that their entropies of brittle relation were equal to 0.006 ± 0.201 i, −0.012 ± 0.221 i, 0.142 ± 0.237 i, and 0.041 ± 0.202 i, respectively. More exactly speaking, the main brittleness influenced on its safety is the environment subsystem in the mine. Therefore, the key to controlling mine accidents is to introduce advanced equipment and improve mechanization level to reach the intrinsic safety of the mining enterprise. The research proves that the modified risk analysis model based on brittleness relation theory is an effective approach to making clear of the state of mine safety and keeping accidents away in time by taking corresponding measures.
Creating an Audio Story with Interactive Binaural Rendering in Virtual Reality
Authors: Geronazzo Michele , Rosenkvist Amalie , Eriksen David Sebastian , Markmann-Hansen Camilla Kirstine , Køhlert Jeppe , Valimaa Miicha , Vittrup Mikkel Brogaard , Serafin Stefania
Published: November 2019

The process of listening to an audiobook is usually a rather passive act that does not require an active interaction. If spatial interaction is incorporated into a storytelling scenario, can open. Possibilities of a novel experience which allows an active participation might affect the user-experience. The aim of this paper is to create a portable prototype system based on an embedded hardware platform, allowing listeners to get immersed in an interactive audio storytelling experience enhanced by dynamic binaural audio rendering. For the evaluation of the experience, a short story based on the horror narrative of Stephen King’s Strawberry Springs is adapted and designed in virtual environments. A comparison among three different listening experiences, namely, (i) monophonic (traditional audio story), (ii) static binaural rendering (state-of-the-art audio story), and (iii) our prototype, is conducted. We discuss the quality of the experience based on usability testing, physiological data, emotional assessments, and questionnaires for immersion and spatial presence. Results identify a clear trend for an increase in immersion with our prototype compared to traditional audiobooks, showing also an emphasis on story-specific emotions, i.e., terror and fear.
As Clinical Markers, Hand-Foot-Skin Reaction and Diarrhea Can Predict Better Outcomes for Hepatocellular Carcinoma Patients Receiving Transarterial Chemoembolization plus Sorafenib
Authors: Liu Lei , Wang Enxin , Li Lin , Chen Dongyu , Peng Kun , Wang Mengmeng , Han Guohong
Published: November 2019

Background. Combination therapy of transarterial chemoembolization plus sorafenib (TACE-S) has been proven to be safe and effective for hepatocellular carcinoma (HCC); however, this combination therapy is associated with a high incidence of adverse events (AEs). Our study focused on the relationships between AEs and treatment outcomes and aimed to discover AE-based clinical markers that can predict the survival benefits of combination treatment. Methods. From January 2010 to June 2014, a total of 235 HCC patients treated with TACE-S were retrospectively enrolled. Major sorafenib-related AEs were prospectively recorded, and their correlations with overall survival (OS) were analysed using time-dependent covariate Cox regression analyses. Results. The majority of the patients (200, 85.1%) were male, and the median age was 51 years old. After two years of follow-up, the median OS of the study population reached 12.4 months. In all, 218 patients (92.8%) presented at least one AE, and 174 (74.0%) suffered AEs ≥2 grade. Based on time-dependent multivariate analyses, the development of hand-foot skin reaction (HFSR) ≥2 grade (HR = 0.43, 95% CI: 0.32–0.58, P<0.001) and diarrhoea ≥1 grade (HR = 0.72, 95% CI: 0.53–0.97, P=0.029) were identified as independent predictors of prolonged OS. Moreover, patients who developed both HFSR ≥2 grade and diarrhoea ≥1 grade achieved better outcomes than those patients who developed either or neither of these AEs (HR = 1.51, 95% CI: 1.11–2.06, P=0.009). Conclusions. The development of HFSR ≥2 grade or diarrhoea ≥1 grade during TACE-S treatment indicated prolonged OS, and these AEs should be considered important clinical markers for predicting patient prognoses.
Effects of Twin Inclined Plane Device on Adaptation and Ultrastructure Variations in Condyle of Growing Rats
Authors: Wang Shuo , Sun Yuhong , Xia Lulu , Li Hanyue , Xu Yan , Hua Xianming
Published: November 2019

Objective. This study investigates the effects of using a twin inclined plane device (TIPD) on the remolding and ultrastructure variation of mandibular condyle in growing rats. Materials and Methods. Forty-eight male Wistar rats (six weeks old, body weight of approximately 190–210 g) were divided into experimental group (wearing appliance, n = 32) and control group (no appliance, n = 16). Samples were collected on days 3, 14, 30, and 60. The immunohistochemical analysis for vascular endothelial growth factor (VEGF) and type II collagen was carried out. Tartrate-resistant acid phosphatase (TRAP) reaction was performed to evaluate the osteoclastic activity. Three-dimensional morphometric images were reconstructed for morphometric analysis by microcomputed tomography (micro-CT). The ultrastructure of the condylar surface was observed by scanning electron microscopy (SEM). Results. The expression of VEGF significantly increased, while the expression of type II collagen decreased in the experimental group at days 30 and 60. Furthermore, the enhanced osteoclast activity was observed under the subchondral bone, which was highest at day 30, and decreased to the lowest at day 60 in the experimental group. In addition, adaptive subchondral bone remolding in the posterior part of the condyle was observed at day 60 in the experimental group, and the SEM revealed the ultrastructure variations after installation of the TIPD. However, these changes began to reverse after 30 days. Conclusion. Condylar tissue changes point to the osteoclastic activity in the posterior region of the condyle. These adaptive changes point to bone resorption in the posterior condyle. Type II collagen and VEGF contribute to the MCC remolding induced by the TIPD. The ultrastructural changes in the posterior condylar area in response to mechanical stresses are recoverable at the initial stage.
A Fractional‐Order Model for Zika Virus Infection with Multiple Delays
Authors: Rakkiyappan R. , Latha V. Preethi , Rihan Fathalla A.
Published: November 2019

Time delays and fractional order play a vital role in biological systems with memory. In this paper, we propose an epidemic model for Zika virus infection using delay differential equations with fractional order. Multiple time delays are incorporated in the model to consider the latency of the infection in a vector and the latency of the infection in the infected host. We investigate the necessary and sufficient conditions for stability of the steady states and Hopf bifurcation with respect to three time delays τ1, τ2, and τ3. The model undergoes a Hopf bifurcation at the threshold parameters , , and . Some numerical simulations are given to show the effectiveness of obtained results. The numerical simulations confirm that combination of fractional order and time delays in the epidemic model effectively enriches the dynamics and strengthens the stability condition of the model.