bluuebunny/crossref_metadata_2025 huggingface dataset:
Withdrawal Resistance of T-Nuts in Various Furniture Materials
Authors: Skorupińska Ewa , Wiaderek Krzysztof , Sydor Maciej
Published: July 2022

T-nuts are factory installed in the holes of the ready-to-assemble furniture components. There is a risk that the t-nut spontaneously falls out during transport or storage and get lost; the t-nut can also be pushed into inaccessible spaces during assembly. These complications can make furniture assembly impossible. For this reason, sufficient force to hold the t-nut in the hole is essential. The article presents the test results of the forces holding the t-nuts in five furniture materials (softwood, Oriented Strand Board, plywood, and particleboard in two variants). The M6 t-nuts with four prongs were installed in predrilled 8 mm holes. The resistance to withdrawal of the t-nuts was measured with a universal testing machine. The tested materials could be divided into three groups in terms of the risk of the t-nut falling out: softwood and plywood – low risk, F = 1113.2-1158.0 N; OSB and particleboard – moderate risk, F = 592.3-645.5 N, particleboard with a pad – high risk, F = 645.5 N. The results show that the withdrawal resistance is not correlated with the density of the wood material, and that it decreased with the degree of wood material processing – the less processed the material, the greater the resistance to withdrawal of the t-nuts.
Colour Change of Steamed Alder Wood Caused by UV Radiation
Authors: Dzurenda Ladislav , Dudiak Michal
Published: July 2022

Alder wood (Alnus glutinosa L.) was steamed with a saturated steam-air mixture at a temperature of t = 95 °C, or saturated steam at t = 115 °C and t = 135 °C to obtain a pale brown colour, a light red-brown colour and a dark brown-grey colour. Subsequently, samples of unsteamed and steamed alder wood were irradiated with a UV lamp in a Xenotest Q-SUN Xe-3-HS after drying in order to test the colour stability of steamed alder wood. The colour change of the wood surface was evaluated by means of measured values on the coordinates of the colour space CIE L*a*b*. The results show that the surface of unsteamed alder wood as well as steamed alder wood with a steam-air mixture at t = 95 °C and saturated steam at t = 115 °C darkened and browned due to photochemical reactions caused by UV radiation. The opposite tendency was recorded at the surface of alder wood steamed with saturated steam with a temperature of t = 135 °C, where the deep dark-brown-grey colour lightened to a brown-reddish colour shade under the influence of UV radiation. The analysis of the changes in the coordinates of the colour space CIE L*a*b* shows that the greater the darkening and browning of the alder wood by steaming, the smaller the changes in the values of ΔL*, Δa*, Δb* of the steamed alder wood caused by UV radiation. The positive effect of steaming on UV resistance is evidenced by the decrease in the overall colour difference ΔE*. While the value of the total colour difference of unsteamed alder wood caused by UV radiation is ΔE* = 10.9, it decreased to ΔE* = 8.7 for alder wood steamed with steam-air mixture at t = 95 °C, which is a decrease of 20.2 %; for alder wood steamed at t = 115 °C it decreased to ΔE* = 6.5, which is a decrease of 40.3 %; and for alder wood steamed with saturated water steam with the temperature t = 135 °C it decreased to ΔE* = 5.7, which is a decrease of 47.7 %.
Influence of Moisture Content on Cutting Parameters and Fracture Characteristics of Spruce and Oak Wood
Authors: Hanincová Luďka , Procházka Jiří , Novák Vít , Kopecký Zdeněk
Published: July 2022

The objective of this study was to determine the effect of the moisture content on cutting parameters and fracture characteristics of spruce and oak wood. Samples of Norway spruce (Picea abies (L.) H. Karst.) and English oak (Quercus robur L.) were dried to required moisture content and then used for the machinability test on circular sawblade machine. Results indicate that cutting force and feed force increase with increasing moisture content up to the fiber saturation point (FSP). When the moisture content increases above the FSP, the minimum values of cutting and feed force are achieved. Based on performed experiments, the fracture toughness and shear yield strength were derived. Fracture toughness decreases with increasing moisture content. The minimum values of fracture toughness are achieved at the moisture content level above the FSP. Shear yield strength decreases linearly with increasing moisture content: the decrease is up to 17 % compared to samples with moisture content at the FSP. Based on calculated results, the influence of moisture content and wood species on cutting and fracture characteristics was discussed.
Kopzorgen voor voetbalclubs
Authors: Hulsbergen Diederik
Published: July 2022

Kopzorgen voor voetbalclubs. Een uitwerking van werkgeversaansprakelijkheid voor acuut hersenletsel bij beroepsvoetballers.

Kopduels tussen beroepsvoetballers kunnen leiden tot hersenschade en de vraag is wie daarvoor aansprakelijk kan worden gesteld. Er is in deze bijdrage dogmatisch onderzoek gedaan naar de vraag in hoeverre beroepsvoetballers met hersenletsel hun schade kunnen verhalen op hun club via artikel 7:658 BW. Uit het onderzoek volgt dat de aard van de werkzaamheden en van de schade een succesvol schadeverhaal sterk bemoeilijken.
Assessing the Impact of Non-Conventional Radar and Surface Observations on High-Resolution Analyses and Forecasts of a Severe Hailstorm
Authors: Morris Matthew T. , Brewster Keith A. , Carr Frederick H.
Published: July 2022

A 2009 National Research Council study recommended that new mesoscale observing networks be integrated with existing networks to form a nationwide “network of networks”. The report also recommended that research testbeds be established, such as the Center for Collaborative Adaptive Sensing of the Atmosphere (CASA) DFW Testbed, to ascertain the potential benefit of proposed observing systems. In this work, we use various conventional and non-conventional observing systems from the DFW Testbed in a series of observing system experiments (OSEs). Of special interest are radar data from Terminal Doppler Weather Radars and CASA X-band radars, as well as novel surface observations. The Advanced Regional Prediction System (ARPS) model is used to perform OSEs that are designed to assess the impact of these observing systems. A three-dimensional variational analysis system and companion complex cloud analysis are used to produce analysis increments, which are assimilated in ARPS using Incremental Analysis Updating. Experiments are performed on a supercell thunderstorm case from 11 April 2016 that produced large, damaging hail. The analysis includes quantitative comparisons of model-derived hail with radar-observed hail, along with verification of surface fields. The CASA radial velocity data benefited the forecasted storm structure, as it positively affected subsequent storm morphology and model-derived hail forecasts. Of note in surface observation impacts, the dewpoint measurements from the non-conventional Earth Networks and CWOP networks slightly degrade the forecasted dewpoint field compared to independent standard observations, but did not prevent the successful prediction of hail.
The integration of CSR within communication as a strategic factor of competitiveness: Bibliometric analysis
Authors: Alarcón-Sánchez Karla María , Soriano-Sandoval José Luis
Published: July 2022

Objective. This document presents the development of the world scientific production of CSR and Corporate Communication.

Methodology: Through a bibliometric analysis, using the Scopus platform and the VOSviewer software as a database for the development of networks between authors and publications.

Findings: in the last 20 years, CSR and CC are considered relevant variables within the field of strategic management.

Originality. The original of the study is the valuable relationship between both variables for the generation of competitive advantage. The study focuse of the study evolves to the analysis of mediating variables and/or micro variables.
Corporate Social Responsibility initiatives with a strategic approach to eradicate the phenomenon of Greenwashing
Authors: Soriano-Sandoval José Luis , Alarcón-Sánchez Karla María
Published: July 2022

Purpose. Establish a multidisciplinary theoretical discussion to determine a possible solution to eradicate and/or reduce greenwashing practices.

Methodology. Through a systematic analysis of the literature and a bibliometric analysis, the results of the growth of greenwashing and its possible solution are obtained.

Findings. The position of using corporate social responsibility practices is theoretically identified, from a strategic approach, which, in turn, allows managers to incorporate said positions, for the creation and development of best responsible practices, from a strategic point, leaving aside the philanthropic vision.

Originality. The research is innovative because it includes strategic management theories in theories related to corporate social responsibility and, in turn, generates practical recommendations to solve the growing problem of greenwashing.

Conclusions and limitations. This research is limited to establishing theoretical criteria, inviting empirical validation of the recommendations in future research.
Teachers’ self-efficacy: sources and the role of the fulfilled professional role
Authors: Strutyńska Elżbieta , Karwowski Maciej
Published: July 2022

Self-efficacy is a vital factor that makes achieving goals more likely. That applies to teachers’ activity as well. The aim of the study presented in this article was to examine whether teachers who differ in the dominant pattern of their professional role perceive themselves as more or less self-efficacious, and whether they see the sources of their self-efficacy differently. We were interested in testing the hypothetical mechanism by which the dominant professional role moderates the relationship between the sources of self-efficacy and the level of self-efficacy. A cross-sectional study on a large sample of Polish teachers (N = 946), demonstrated differences in the perceived sources of self-efficacy among teachers who defined their roles differently. Although the level of teachers’ self-efficacy was similar in the groups of teachers with different dominant professional roles, we noted the moderating effect of the professional role for the relationship between the four sources of self-efficacy and self-efficacy.
ANALISIS FAKTOR PENGGUNAAN MEDIA UNTUK PEMBELAJARAN JARAK JAUH (STUDI KASUS : SDIT AL IMAN BINTARA)
Authors: Husni Tissa Maharani
Published: July 2022

Pandemi Covid 19 memaksa banyak bidang untuk beradaptasi, termasuk bidang pendidikan. Hingga akhirnya Mendikbud mengeluarkan Surat Edaran Nomor 4 Tahun 2020 mengenai  pembelajaran daring atau jarak jauh. Pembelajaran jarak jauh menerapkan sistem pembelajaran yang tidak berlangsung dalam suatu ruangan kelas, sehingga hanya mungkin dilakukan dengan memanfaatkan media teknologi infomasi dan komunikasi. Penelitian ini mencoba menganalisis media apa yang digunakan dan faktor apa yang menjadi alasan pemilihan dan penggunaan media teknologi informasi dan komunikasi selama pembelajaran jarak jauh berdasarkan indikator persepsi kemudahan penggunaan (Perceived Ease of Use), persepsi kegunaan (Perceived Usefulness), niat perilaku untuk menggunakan (Behaviour Intention to Use), sikap terhadap perilaku (Attitude Toward Behaviour) dan pemakaian secara nyata (Actual Use) dalam metode Technology Acceptance Model (TAM). Pengumpulan data menggunakan instrumen kuesioner dengan metode purposive sampling, wawancara, dan observasi. Subjek penelitian adalah 10 guru kelas satu di SDIT Al Iman Bintara. Hasil penelitian ini disimpulkan bahwa media yang paling banyak digunakan adalah Zoom, Edmodo dan WhatsApp. Variabel kemudahan penggunaan, variabel kegunaan dan variabel niat perilaku untuk menggunakan, masing-masing sama-sama memiliki hubungan sangat kuat, positif dan signifikan dengan variabel pemakaian secara nyata, sedangkan variabel sikap terhadap perilaku memiliki hubungan yang cukup dengan variabel pemakaian secara nyata.
Terapi Non Farmakologi dalam Pengendalian Tekanan Darah Pada Pasien Hipertensi: Systematic Review
Authors: Ainurrafiq Ainurrafiq , Risnah Risnah , Ulfa Azhar Maria
Published: July 2022

Diketahuinya penerapan terapi non farmakologik pengendalian tekanan darah pada pasien hipertensi dari berbagai perbandingan. Sumber perncarian jurnal pada penelitian ini adalah Google Schoolar, DOAJ dan Portal Garuda artikel yang diterbitkan dari tahun 2015-2018, jurnal intervensi untuk mengatasi tekanan darah pada pasien hipertensi, merupakan intervensi non farmakologi, merupakan intervensi yang efisien berdasarkan hasil penelitian dan intervensi yang mudah dilakukan. Berdasarkan pada sepuluh artikel sesuai dengan kriteria inklusi. Berdasarkan sepuluh artikel tentang terapi non farmakologik dalam pengendalian tekanan darah pada pasien hipertensi membuktikan bahwa 100% terapi non farmakologik efektif dalam menurunkan tekanan darah pada pasien hipertensi. Teknik non farmakologik yang digunakan dalam jurnal yang terpilih yaitu, pemberian juice campuran tomat dan mentimun, pemberian juice belimbing dan buah naga, pemberian jus papaya mengkal dalam, pemberian madu, relaksasi menggenggam jari dan nafas dalam, terapi bekam, pemberian air rebusan daun salam, pemberian terapi music suara alam, terapi Healing Touch, dan terapi Slow Deep Breating  Berdasarkan 10 jurnal yang terpilih sesuai dengan kriteria inklusi, terapi non farmakologik yang efektif dalam mengendalikan tekanan darah pada  pasien hipertensi adalah pemberian juice campuran tomat dan mentimun, pemberian madu, terapi relaksasi genggam jari dan nafas dalam, terapi music suara alam dan slow deep breating
SUMBER KELEMAHAN UMAT ISLAM
Authors: Sagirah Sitti
Published: July 2022

Penelitian ini: mendeskripsikan hadis tentang umat Islam bagaikan buih kemudianmengkritik otentisitasnya, menganalisis kandungan dan implementasinya dalamkonteks kekinian. Metode yang digunakan adalah metode tahli>li dan tehnikinterpretasi tekstual, intertekstual, dan kontekstual dengan pendekatan multidisipliner.Sebelum mengkritik otentisitas hadis berdasarkan kaidah kesahihan hadis, terlebihdahulu melakukan takhri>j al-hadi>s\ dengan menggunakan kata kunci yu>syiku alumam. Setelah mengetahui kualitas hadis sebagai hadis sahih, maka dilanjutkandengan studi ma‘a>ni> al-hadis. Hasil penelitian menunjukkan bahwa hadis Nabi saw.riwayat Ahmad bin Hanbal No. 21363, ‚umat Islam bagaikan buih‛ berkualitassahih. Dalam hadis tersebut, Nabi saw. menyebutkan rendahnya kualitas persatuandan solidaritas umat Islam, dan penyakit wahn merupakan sumber lemahnyaumat Islam akhir zaman. Solusi alternatif yang ditawarkan adalah membangunsinergitas internal umat Islam dan menerapkan kehidupan spiritualitaskesederhanaan.
TEACHING ENGLISH IN THE DIGITAL ERA
Authors: Hasanah Nur Izatil
Published: July 2022

The global use of technology might have influenced all of education institutions to follow the current trend of the technological usage. The use of information and communication technology or ICT become a key role in improving education.The study aimed to determine the digital tools utilized by the teachers and how the English teachers perceived teaching English in the digital era, how English teachers cope with the technological innovations and the way they look at the future of English teaching and learning with advent of digital learning. The study employed the qualitative method with interview as the instruments in gathering data among the 10 English teachers at USANT, Iriga City, Philippines. Results show that the respondents or key informants the most widely used are mobile phone, laptop, tablets, computer, e-mail, and Google Translator, while the least widely used are Grammarly, MOOC and Kahoot!. Google Classroom, Edmodo, digital boards, and Quizlet. Moreover, English teachers cope with technological innovations in three ways: first, is by learning through self- discovery; second, by attending trainings and seminars related to technology and digital learning and third, by seeking help from peers. This research concluded that the English teachers use digital tools for English language teaching as supplemental aids; that technology cannot substitute an English teacher; English teachers cope with the technological innovations gradually be learning by themselves, with others and by attending seminars; the English teachers are responsive to the changes in technology.
PENERAPAN PROGRAM KUNJUNGAN RUMAH DALAM MATA PELAJARAN BAHASA INDONESIA DI SEKOLAH DASAR
Authors: Mahyudi Arni
Published: July 2022

Bahasa Indonesia merupakan salah satu pelajaran yang diajarkan sejak jenjang pendidikan dasar sampai ke perguruan tinggi. Pembelajaran bahasa Indonesia yang dilakukan di tingkat sekolah dasar dengan pembelajaran daring memang dirasakan belum begitu optimal dikarenakan kendala tidak semua siswa yang memiliki media telepon genggam. Di samping itu, kendala jaringan komunikasi juga menjadi hal yang patut dipertimbangkan. Penelitian ini menggunakan pendekatan kualitatif jenis studi kasus. Pengumpulan data dilaksanakan melalui observasi, wawancara, dan dokumentasi. Teknik analisis data yang digunakan adalah reduksi data, display data, dan penarikan kesimpulan. Peneliti menggunakan triangulasi teknik dan triangulasi sumber untuk memperoleh keabsahan data. Berdasarkan hasil penelitian dapat disimpulkan bahwa program kunjungan rumah yang dilaksanakan guru bahasa Indonesia ada beberapa tahap yaitu tahap observasi, perencanaan, pelaksanaan, evaluasi, dan tindak lanjut.
ANALISIS KESALAHAN BERBAHASA ARAB MAHASISWA STIT IBNU RUSYD
Authors: M.Pd Nukman
Published: July 2022

Manusia adalah makhluk pembelajar. Saat pembelajaran berlangsung sering terjadi kesalahan, maka dari kesalahan tersebut mereka kembali belajar untuk memperbaiki dan terhindar dari kesalahan yang sama. Begitu juga dalam pembelajaran Bahasa Arab, terkadang terjadi kesalahan. Namun beberapa pembelajar tidak menyadari bahwa Bahasa Arab yang digunakan terdapat kesalahan. Dengan menganalisis kesalahan-kesalahan tersebut diharapkan para pembelajar bahasa Arab meminimalkan kesalahan dalam bahasanya. Penelitian ini bertujuan untuk mendiskripsikan dan mengeksplor: 1) Bentuk kesalahan berbahasa Arab, 2) Penyebab kesalahan, 3) Perbaikan kesalahan. Penelitian ini menggunakan pendekatan analisis isi kualitatif terhadap kesalahan berbahasa Arab pada Mahasiswa Sekolah Tinggi Ilmu Tarbiyah (STIT) Ibnu Rusyd Program Studi Pendidikan Agama Islam Semester II Tahun Ajaran 2019/2020 dalam pembelajaran Bahasa Arab C. Hasil penelitian menunjukkan bahwa ada empat jenis kesalahan yang dilakukan mahasiswa, yaitu: fonologi, morfologi, sintaksis, dan diskursus. Kata Kunci: Analisis Kesalahan, Fonologi, Morfologi, Sintaksis, dan Diskursus
PERAN KEPEMIMPINAN KIAI DALAM MENANGKAL RADIKALISME DI PONDOK PESANTREN NURUL MUHIBBIN PASER
Authors: Mardani Mardani
Published: July 2022

Kiai berkewajiban memberikan pemahaman ajaran agama Islam yang benar kepada santrinya dan juga menjaga agar para santri tidak terpengaruh dengan pemahaman yang dapat merusak agamanya salah satunya adalah pemahaman radikalisme yang berbuntut pada beberapa tindakan terorisme yang membahayakan orang lain. Maka dari itu, dalam penelitian ini memiliki tujuan untuk menganalisis peran kepemimpinan kiai dalam menangkal paham radikalisme di pondok pesantren salah satunya yaitu Pondok Pesantren Nurul Muhibbin Paser. Penelitian ini menggunakan pendekatan sosiologis, kemudian dilakukan observasi, interview dan dokumentasi untuk mengumpulkan data. Selanjutnya data di analisis dengan mereduksi data dan terakhir di uji keabsahannya dengan metode triangulasi. Dalam penelitian ini seorang kiai setidaknya memiliki tiga peran dalam kepemimpinannya di pondok pesantren untuk menangkal radikalisme yaitu, menjadi teladan, pengambil keputusan dan pembimbing.
La selectividad estratégica del Estado en el Instituto Nacional de Vitivinicultura en el período 1991 – 2001
Authors: Hernández Juan Jesús
Published: July 2022

El artículo tiene como objetivo analizar la selectividad estratégica del Instituto Nacional de Vitivinicultura (INV) en el período 1991 – 2001. La pregunta es: ¿los intereses de qué sector de la vitivinicultura privilegió el INV?. El trabajo toma como marco teórico el Enfoque Estratégico Relacional (EER) y parte de la hipótesis que el INV tiene una “selectividad estratégica” que lo lleva a privilegiar algunos intereses sobre otros. Las acciones estatales tienen un efecto sobre los agentes (y sus relaciones de poder) y a su vez éstos despliegan estrategias para lograr control de esos organismos mediante la participación en su conducción y/o la definición de sus políticas. El trabajo muestra cómo el INV colaboró con la implementación de un modelo de producción que favoreció a los grandes bodegueros y cedió parte del poder que tuvo en las décadas anteriores en favor de los gobiernos de San Juan y Mendoza.
Pectin and Its Applicability in Food Packaging
Authors: Younis Heba , Zhao Guohua , Abdellatif Hassan
Published: July 2022

Food packaging based on plastic films made from nonrenewable resources often causes environmental problems after disposal. Recently, researchers are increasingly focusing on alternative materials to reduce the use of nonbiodegradable and nonrenewable films. Generally, biomaterials are nontoxic, biocompatible, and renewable always presents reasonable film-forming ability. Thus, they are important for food safety, where undesired chemical compounds might migrate from chemicals migrate from the plastic packaging materials into foods. Pectin (PEC), as a natural carbohydrate polymer, belongs to the anionic heteropolysaccharide family and is often extracted from various residues from plant food processing, such as apple and citrus pomaces. The pectin molecules are highly branched with a backbone α-(1–4) linked D galacturonic acid. Among the naturally derived carbohydrate-based biopolymers, pectin was considered a promising substrate in fabricating edible films due to its diverse advantages, such as perfect film-forming ability, evidenced bioactivity, easy availability, and excellent quality biodegradability and biocompatibility, nontoxicity, and low cost. Pectin-based films have excellent oxygen barrier capacity and extend the shelf life for different fruits. The properties of pure pectin films can enhance through combination with other polymers or nanoparticles/fibers.
Non-invasive Brain Stimulation Post Stroke
Authors: Somaa Fahad
Published: July 2022

Stroke is the second most common cause of death and dementia and the first most common cause of disability in developed nations. Tissue in the penumbra may be salvaged by reperfusion treatment using recombinant tissue plasminogen activator or thrombectomy with a stent retriever, which improves the ultimate neurological prognosis. However, because of the limited therapeutic window of 6 hours, it is only available to 5–10% of the community. Non-invasive brain stimulation (NIBS) has recently gotten a lot of interest for its potential involvement in stroke recovery. When used correctly, NIBS methods employ electrical and magnetic stimulation to modify the excitability of deep brain tissue without harming it. This may result in long-term neuroplastic modifications. Based on different protocols, stimulation to the cerebral cortex can be either excitatory or inhibitory. This has led to NIBS being used therapeutically to alleviate depression. In recent years, stroke patients have been studied to see whether NIBS has therapeutic benefits on cognitive skills.
Effects of Veld Degradation on Biomass Production in the Arable Lands of South Africa
Authors: Madolo Nkosikhona , B. Lewu Francis
Published: July 2022

This paper reviews the impacts of veld degradation on species diversity, veld ecological condition. The major focus of this review is to assess the major critical factors that contributeto veld degradation. It is imperative to revitalize information on the effects of veld degradation in the South African pastoral farming systems. Current studies have indicated the limited research gaps that identify the adverse effects of veld degradation on species composition and biomass production. Grazing behavior in different grazing patterns has not been clear. Finally, this review will assist farmers, policymakers, and pastoralists to broaden their knowledge on policy development, and appropriate the veld management practices, coping measures of veld degradation, particularly those from resource-poor communities. Whereby, livestock production is the focus for food security and poverty alleviation. However, the use of legumes intercropped with temperate grass species can improve animal performance and herbage production during critical periods. The review further evaluates the veld management practices and their ability in providing adequate foliar cover with the use of the edible perennial grass plant that ensures long-term sustainable production with maximum economic returns during critical grazing seasons.
Impact of the Spreading of Sludge from Wastewater Treatment Plants on the Transfer and Bio-Availability of Trace Metal Elements in the Soil-Plant System
Authors: Lassoued Najla , Essaid Bilal
Published: July 2022

The spreading of sludge from sewage treatment plants increased the production of durum wheat and rapeseed. Their richness in nitrogen, phosphorus, and potassium gives them a beneficial effect on crops. However, the application of the sludge can induce increases in the concentration of metals in plant tissues. This increase can generate disturbances at the level of the cell and organelles, such as mitochondria and chloroplasts, which can be altered. Repeated applications of the sludge on the same site tend to increase the accumulation of heavy metals in the soil, so that an cause toxicities for soil microorganisms, animals, and humans, via the food chain. However, it is important to specify that these nuisances mainly concerned industrial sludge, but the use of this sludge is strictly prohibited. In addition, the high doses used in our field experiments are significantly higher than those authorized in agricultural practice. Finally, the risk assessment by calculating both the level of consumer exposure and the number of years for soil saturation shows that the use of urban sludge is safe, especially in the short and medium-term. Nevertheless, the quality of the sludge to be spread must be constantly monitored.
Leukaemia: The Purinergic System and Small Extracellular Vesicles
Authors: Ude Arinzechukwu , Okeke Kelechi
Published: July 2022

Haematopoiesis is a tightly regulated process, by intrinsic and extrinsic factors, to produce lifelong blood cell lineages within the bone marrow. In the bone marrow microenvironment, mesenchymal stem cells and haematopoietic stem cells play important roles to ensure that haematopoiesis is maintained. These cells contain purines and pyrimidines that control intercellular process such as energy transport. However, in some cases, this process may be misregulated thus leading to the production of various diseases, including leukaemia. As a result, bone marrow cells may be stimulated via stress or induced hypoxia, and this leads to the release of purine and pyrimidine nucleotides and nucleosides into the extracellular space, and activation of autocrine/paracrine feedback loops. These extracellular nucleotides and nucleosides, and their respective cell surface receptors are involved in purinergic signaling that control different physiologic functions in cells including proliferation, differentiation, and cell death. These extracellular nucleotides and nucleosides include ATP, UTP, adenosine diphosphate (ADP), UDP and adenosine however the most important players are ATP and its metabolite adenosine. ATP is degraded via a sequential activity of ectonucleotidases. ATP, adenosine and these ectonucleotidases play very important roles in the tumour microenvironment crucial to disease development, progression, and aggressiveness by modulating immune response to leukaemia treatment and increasing homing of leukaemic cells.
Study of the Critical Behavior in La0.67Ca0.18Sr0.15Mn0.98Ni0.02O3 Manganite Oxide
Authors: Laajimi Kawther , Hichem Gazzah Mohamed , Dhahri Jemai
Published: July 2022

In order to study the critical behavior of La0.67Ca0.18Sr0.15Mn0.98Ni0.02O3 near room temperature, magnetization measurements were performed. It can be seen from the findings that the specimens show a second order phase transition. Given the relative slope, the 3D-Ising model was deduced as the most suitable model. It was found that the evaluated critical exponents were β = 0.320, γ = 1.296 and δ = 4.965 at TC = 319 K. These verify the Broadom’s scaling equation δ = 1 + γ/β, which demonstrates that our values have been proved valid. Near TC magnetization-strength-temperature, (M-μ0H-T) results fell in two curves according to critical exponents, obeying the single scaling equation Mμ0Hε=εβʄ±μ0H/εβ+γ with ε=T−Tc/Tc as the reduced temperature.
Endoplasmic Reticulum: A Hub in Lipid Homeostasis
Authors: Ventura Raúl , Isabel Hernández-Alvarez María
Published: July 2022

Endoplasmic Reticulum (ER) is the largest and one of the most complex cellular structures, indicating its widespread importance and variety of functions, including synthesis of membrane and secreted proteins, protein folding, calcium storage, and membrane lipid biogenesis. Moreover, the ER is implicated in cholesterol, plasmalogen, phospholipid, and sphingomyelin biosynthesis. Furthermore, the ER is in contact with most cellular organelles, such as mitochondria, peroxisomes, Golgi apparatus, lipid droplets, plasma membrane, etc. Peroxisomes are synthesized from a specific ER section, and they are related to very-long-chain fatty acid metabolism. Similarly, lipid droplets are vital structures in lipid homeostasis that are formed from the ER membrane. Additionally, there is a specific region between the ER-mitochondria interface called Mitochondria-Associated Membranes (MAMs). This small cytosolic gap plays a key role in several crucial mechanisms from autophagosome synthesis to phospholipid transfer. Due to the importance of the ER in a variety of biological processes, alterations in its functionality have relevant implications for multiple diseases. Nowadays, a plethora of pathologies like non-alcoholic steatohepatitis (NASH), cancer, and neurological alterations have been associated with ER malfunctions.
Sustainable and Eco-Friendly Biomass Derived Biochars for the Removal of Contaminants from Wastewater: Current Status and Perspectives
Authors: Tyagi Uplabdhi , Anand Neeru
Published: July 2022

Human activities and rapid modernization have affected the ecological and economical aspects worldwide resulting in alarming situations such as global warming and the accumulation of waste disposal and toxic contaminants in water. Contaminants in water are toxic and carcinogenic, posing a serious threat to the environment. Water is a precious and limited resource and hence it is highly imperative to utilize effective remediation strategies for the removal of pollutants. Several competitive remediation techniques have been proposed due to their distinctive features including ease of operation, inexpensiveness and universal nature. The present chapter highlights the potential of ecofriendly biomass-derived biochars as adsorbents for the effective removal of toxic contaminants. This includes biochars derived from industrial solid wastes, agricultural wastes, clays minerals and municipal wastes. Biomass-derived biochars are found to be highly efficient, alternative and carbon-neutral precursors and provide a new approach to the modular adsorption process. The present chapter also includes conversion of waste materials into efficient bio-adsorbents followed by their applications for the purification of wastewater. Besides, attempts are made to discuss the techno-economic and future perspectives of eco-friendly and low-cost biochars for the treatment of wastewater.
The Advantage of Single-Payer National Insurance
Authors: Thabrany Hasbullah , Sayekti Mutia
Published: July 2022

The world leaders have committed to achieve universal health coverage as set on the goal of 3.8 of the SDGs by 2030. Only public financing could achieve UHC for everyone in a country. There are three sources of public financing, i.e., tax-funded or national health service system, social health insurance applied national or national health insurance scheme, and a combination of the two. Low- and middle-income countries are often easier to start with social health insurance schemes with multiple and single schemes. The option of a single-payer National Health Insurance scheme has a lot of advantages in terms of effectiveness, efficiencies, and equitable health financing for all people in a country. This chapter explains the rationales of health financing and options of public financing with various levels of the impacts on the people in particular and the country. A single-payer system facilitates easy understanding and ensures equitable access with the same benefits for everybody. A single-payer system also potentially has monopsony powers to ensure cost-effective health care. Expenditures data demonstrate relatively lower among single-payer systems with the relatively the similar health outcomes.
The Comparison of the Effectiveness of Cognitive Rehabilitation and Transcranial Direct Current Stimulation on Executive Functions of Combat Veterans with Posttraumatic Stress Disorder
Authors: Faraji Reza , Oraki Modammad , Zare Hosein , Nejati Vahid , Moradi Ayoub
Published: July 2022

Background: According to the fact that executive functions are set of interrelated skills that highly influence the standards of living of the surviving combat veterans, this research was conducted with the aim of examining the effect of cognitive rehabilitation and Transcranial direct current stimulation (TDCS) on the executive functions of surviving combat veterans with PTSD. Methods: In quasi-experimental research, 60 combat veterans with PTSD in Kermanshah were chosen by convenience sampling method and randomly assigned to four experimental groups (2 treatment groups, placebo/sham group, a control group). In order to collect data, the Barclays Psychological Performance Disorder Assessment Questionnaire (BDEFS), and Post-traumatic Stress Disorder List (Wooders et al. 1994) were applied. The obtained data were analyzed by applying Multivariable Analyze of Covariance. Results: The results of the Fisher's Least Significant Difference (LSD) Post-Hoc test showed that TDCS is more effective than Cognitive Rehabilitation in promoting self-control/ inhibition, self-motivation, emotion self-regulation, and total score of executive functions (P < 0.01) and (P < 0.05). Finally, the results indicated that the post-test results were repeated in the follow-up test and this represents the stability of the effectiveness of TDCS and Cognitive Rehabilitation on the mentioned constructs. Conclusions: The results of the current research can be used as a new approach to reduce the problems of veterans with PTSD, and enhance the quality of their life by improving their executive functioning.
Impact of packaging design method of cultural heritage with Biotechnology
Authors: Zhiwei Liu , Fan Xu
Published: July 2022

Packaging is an important element in marketing, as it helps to communicate the message of the product and blends in with the market trends. Packaging design has been an effective tool for food manufacturers to express their own values, enhance customer’s perceptions and experience of using the product. However, recent packaging design, such as cartons with textured surfaces or geometric shapes that signal a new kind of energy-efficient insulation technology have become more common and wide spread across many sectors. Meanwhile, bio-technology has been developing rapidly in recent years and research on packaging design oriented at biotechnology is emerging gradually. Experimental results: the average printing time of the intangible cultural heritage product packaging personalized design method in this paper and the other two intangible cultural heritage product packaging personalized design methods is 23.987h, 28.577h and 28.149h, which proves that the intangible cultural heritage product packaging personalized design method integrating 3D printing has higher application value.
Research on intellectual property protection, innovation, and data protection algorithm based on wireless communication network
Authors: Yu Huan
Published: July 2022

In today's world, with the developing technologies, data protection has become an absolute requirement, many organizations are focusing on the security of the data and information. Because many unauthorized individuals can hack computer system, putting the confidential files of the organization at danger. Therefore, there is need to employ various data security techniques in order to secure information. Furthermore, to resolve the problem of high energy consumption caused by large amount of data transmission in data protection algorithm, a data protection algorithm based on wireless communication network is proposed. Furthermore, we investigated that nowadays the protection of intellectual property is become significant issue. Because intellectual property security is essential for promoting innovation. Without intellectual property protection, individuals and firms would not gain the full advantages of their creations and would devote less time to development. The communication channel and data transmission link are established. Each node calculates the residual energy when clustering and sends it to the cluster head before the link is generated. The random number of nodes is encrypted and sorted according to the order of data link. Based on the wireless communication network, the privacy data within and between clusters are fused, and the data difference of each node is calculated respectively. Each cluster head uses homomorphic transformation to realize data sharing. The data protection algorithm is designed. The node data is partitioned and encrypted and decrypted by hybrid operation. The fusion results are uploaded to the base station to complete data protection. Apart from this, in this research, we proposed various methodologies in order to secure information as much as possible including text, photography, forms, videos and many more. Experimental results show that compared with CPDA algorithm, CMT algorithm and HRCDA algorithm, the data protection algorithm designed in this paper consumes the least total energy in each round. The algorithm can protect the privacy of data, reduce the consumption of data, and extend the life cycle of the whole network.
Analysis of static behavior of ion sensitive field effect Transistor for pH measurements
Authors: Kevkić Tijana , Maity Reshmi , Todorović Dragana , Vučković Biljana , Maity N.
Published: July 2022

The Ion-Sensitive Field-Effect Transistor (ISFET) is one of the most popular pH sensors traditionally using to measure hydrogen ion concentration (pH) of the electrolytic solutions. It is developed from Metal Oxide Semiconductor Field-Effect Transistor (MOSFET) by replacing gate electrode with an electrolytic solution to be tested, and a reference metal electrode immersed in that solution. Basic principle of ISFET operation is based on that of standard NMOS structure in conjunction with the insulator-electrolyte capacitor as described in this paper. The site-binding theory (generalized to two kinds of binding sites), together with the Gouy-Chapman-Stern model for the potential profile in the electrolyte, is coupled to the MOS physics. As a result, an approximate analytical model which completely describes static behavior of the ISFET is obtained. The developed description can serve as useful tool for understanding many contemporary biosensors based on original ISFET structure which has broad application in bio-medicine, biological, chemistry and environmental areas.
Editorial V.15N.37
Authors: Silveira Icléia , Paschoarelli Luis Carlos , Ferreira Marcelo Gitirana Gomes
Published: July 2022

Editorial V.15N.37
Conforto no vestuário plus size: inovação e tecnologia têxtil com foco no usuário
Authors: Goulart Daniel , Seibel Silene , Maciel Dulce Maria Holanda
Published: July 2022

Os produtos de vestuário plus size devem atender aspectos relacionados ao conforto do corpo. Assim, a relevância deste estudo está nas necessidades destacadas pelo consumidor relacionadas ao conforto, bem como na disseminação de pesquisas em torno da diversidade social. Seu objetivo é apresentar alternativas inovadoras de vestuário, com base nos requisitos para desenvolvimento de produtos plus size, que por meio da tecnologia têxtil garantam maior conforto ao consumidor. Trata-se de uma pesquisa de natureza básica, qualitativa quanto à abordagem do problema e descritiva quanto aos objetivos, com base teórica sobre livros e trabalhos científicos. O presente estudo traz resultados – como a proposta de produtos inovadores desenvolvidos por meio da criação e aplicação de uma metodologia híbrida para a criação de novos produtos – que, por meio de materiais específicos e processos produtivos, podem atender as necessidades de conforto do consumidor plus size.
Tensile tests at 77 K and 4 K on 316L stainless steel welded plates
Authors: Weeks Timothy , Derimow Nicholas , Benzing Jake
Published: July 2022

Based on the collaborative framework established between ASME, NASA, and NIST, quasi-static tensile tests were performed in liquid nitrogen (77 K) and liquid helium (4 K) on tensile specimens extracted from the centers of four welded 316L stainless steel plates, each produced by a different vendor. Relatively large differences in strength, elongation, and reduction in area were observed between the welds with the strongest two welds (W4 and W2) exhibiting a nearly 20 % difference in 4 K ultimate tensile strength when compared to the welds with the lowest 4 K tensile strength (W1 and W3). As the testing temperature decreases from 77 K to 4 K, all welds exhibit an increase in yield strength, plus an attenuation in total elongation and reduction in area. Serrated yielding was observed at every test conducted at 4 K. The tensile properties reported in this work will be used during analysis of future fracture toughness (single edge notch bending) testing conducted at 77 K and 4 K on the same four sets of welded plates.
Methods of Analyzing Copywriting Texts in the Classroom: Russian-speaking and English-speaking Experience
Authors: Shuiskaya Yuliya Viktorovna , Drozdova Ekaterina Aleksandrovna , Mul'tanovskaya Dar'ya Vladimirovna , Kokorina Mariya Vladislavovna
Published: July 2022

The subject of the study is the texts of copywriting, considered in the methodological aspect. The object of the research is to find the method of identifying manipulative techniques in copywriting texts and studying it in Russian and English classes in higher educational institutions. The authors consider in detail such aspects of the topic as the implicature of copywriting texts, hidden manipulative influences. Particular attention is paid to the need to study copywriting texts not only as potential creators of texts, but also as their consumers, which is necessary for representatives of any profession. Copywriting texts need to be studied not only in the aspect of production, but also in the aspect of perception. The main conclusions of the study are the need to integrate the analysis of copywriting texts into the course of Russian as a native language and English as a foreign language. A special contribution of the authors to the research of the topic is a comparative analysis of copywriting texts in Russian and English in a comparative aspect. The novelty of the research lies in the appeal to the materials of copywriting texts not in the aspect of their effective writing, but in the aspect of effective consumption. The analysis showed that even the texts posted on the websites of state institutions and state-funded programs are written in compliance with the laws of copywriting and with elements of manipulation of the reader, which must be learned to recognize.
Deconstructing cold-induced brown adipocyte neogenesis in mice
Authors: Burl Rayanne B , Rondini Elizabeth Ann , Wei Hongguang , Pique-Regi Roger , Granneman James G
Published: July 2022

Cold exposure triggers neogenesis in classic interscapular brown adipose tissue (iBAT) that involves activation of β1-adrenergic receptors, proliferation of PDGFRA+ adipose tissue stromal cells (ASCs), and recruitment of immune cells whose phenotypes are presently unknown. Single-cell RNA-sequencing (scRNA-seq) in mice identified three ASC subpopulations that occupied distinct tissue locations. Of these, interstitial ASC1 were found to be direct precursors of new brown adipocytes (BAs). Surprisingly, knockout of β1-adrenergic receptors in ASCs did not prevent cold-induced neogenesis, whereas pharmacological activation of the β3-adrenergic receptor on BAs was sufficient, suggesting that signals derived from mature BAs indirectly trigger ASC proliferation and differentiation. In this regard, cold exposure induced the delayed appearance of multiple macrophage and dendritic cell populations whose recruitment strongly correlated with the onset and magnitude of neogenesis across diverse experimental conditions. High-resolution immunofluorescence and single-molecule fluorescence in situ hybridization demonstrated that cold-induced neogenesis involves dynamic interactions between ASC1 and recruited immune cells that occur on the micrometer scale in distinct tissue regions. Our results indicate that neogenesis is not a reflexive response of progenitors to β-adrenergic signaling, but rather is a complex adaptive response to elevated metabolic demand within brown adipocytes.
Active ingredients and molecular targets of Taraxacum mongolicum against hepatocellular carcinoma: network pharmacology, molecular docking, and molecular dynamics simulation analysis
Authors: Zheng Yanfeng , Ji Shaoxiu , Li Xia , Feng Quansheng
Published: July 2022

Background

Taraxacum mongolicum (TM) is a widely used herb. Studies have reported that TM exhibits growth-inhibitory and apoptosis-inducing on multiple tumors, including hepatocellular carcinoma (HCC). The active ingredients, targets, and molecular mechanisms of TM against HCC need to be further elucidated.

Methods

We identified the active ingredients and targets of TM via HERB, PubChem, SwissADME, SwissTargetPrediction, and PharmMapper. We searched HCC targets from GeneCards, Comparative Toxicogenomics Database (CTD), and DisGeNET. Then, the intersection of drug targets and disease targets was uploaded to the STRING database to construct protein-protein interactions (PPI) networking whose topology parameters were analyzed in Cytoscape software to screen hub targets. Next, we used Metascape for Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis, and we employed AutoDock vina, AMBER18 and PyMOL software along with several auxiliary tools for molecular docking and molecular dynamics (MD) simulation. Finally, based on the in silico findings, cellular experiments were conducted to investigate the effect of TM on HSP90AA1 gene expression.

Results

A total of 228 targets and 35 active ingredients were identified. Twenty two hub targets were selected through PPI networking construction for further investigation. The enrichment analysis showed that protein kinase binding, mitogenactivated protein kinase (MAPK) and phosphatidylinositol 3-kinase (PI3K)/Akt signaling pathways were mainly involved. Molecular docking and MD simulation results supported good interaction between HSP90 protein and Austricin/Quercetin. The in vitro assay showed that TM inhibited the proliferation of HepG2 cells and the expression of HSP90AA1 gene.

Conclusions

This study is the first to use network pharmacology, molecular docking, MD simulation and cellular experiments to elucidate the active ingredients, molecular targets, and key biological pathways responsible for TM anti-HCC, providing a theoretical basis for further research.