bluuebunny/crossref_metadata_2025 huggingface dataset:
Letter: elevated liver enzymes and outcome in COVID‐19
Authors: Elhence Anshuman , Kumar Ramesh , Shalimar
Published: September 2023

LINKED CONTENT

This article is linked to Kulkarni et at papers. To view these articles, visit https://doi.org/10.1111/apt.15916 and https://doi.org/10.1111/apt.16028
Editorial: intended victim or innocent bystander? The liver in COVID‐19
Authors: Packer Greg , Bangash Mansoor N.
Published: September 2023

LINKED CONTENT

This article is linked to Huang et al papers. To view these articles, visit https://doi.org/10.1111/apt.15962 and https://doi.org/10.1111/apt.16046
Letter: the risk of gastrointestinal bleeding in patients taking third‐generation P2Y12 inhibitors compared with clopidogrel
Authors: Zhao Jian
Published: September 2023

LINKED CONTENT

This article is linked to Abraham et al paper. To view this article, visit https://doi.org/10.1111/apt.15790
Editorial: FAST score‐ a new predictive marker for HCC after SVR—author's reply
Authors: Ogawa Eiichi
Published: September 2023

LINKED CONTENT

This article is linked to Ogawa et al and Joshita and Umemura papers. To view these articles, visit https://doi.org/10.1111/apt.15976 and https://doi.org/10.1111/apt.16012
Letter: unknown denominator and misleading conclusions in COVID‐19
Authors: Rodríguez‐Perálvarez Manuel , Salcedo Magdalena , Pons José Antonio , Colmenero Jordi ,   the Spanish Society of Liver Transplantation (SETH)
Published: September 2023

LINKED CONTENT

This article is linked to Garrido et al papers. To view these articles, visit https://doi.org/10.1111/apt.15813 and https://doi.org/10.1111/apt.16056
Letter: severe COVID‐19 infection and biologic therapies—a cohort study of 7 808 patients in France
Authors: Bataille Pauline , Amiot Aurélien , Claudepierre Pascal , Paris Nicolas , Neuraz Antoine , Lerner Ivan , Garcelon Nicolas , Rance Bastien , Grisel Olivier , Moreau Thomas , Bernaux Melodie , Audureau Etienne , Sbidian Emilie ,   the AP‐HP/Universities/Inserm COVID‐19 Research collaboration and on behalf of ‘Entrepôt de Données de Santé’ AP‐HP Consortium (appendix)
Published: September 2023

LINKED CONTENT

This article is linked to Taxonera et al and Taxonera & Alba papers. To view these articles, visit https://doi.org/10.1111/apt.15804 and https://doi.org/10.1111/apt.16055
Letter: gastrointestinal symptoms pre‐admission are associated with greater severity of COVID‐19—authors' reply
Authors: Tian Yuan , Rong Long
Published: September 2023

LINKED CONTENT

This article is linked to Tian et al and Yu et al papers. To view these articles, visit https://doi.org/10.1111/apt.15731 and https://doi.org/10.1111/apt.15985
Editorial: intended victim or innocent bystander? The liver in COVID‐19—Authors' reply
Authors: Huang Haijun , Chen Shanshan , Li Hong , Zhou Xian‐Long , Dai Yining , Wu Jia , Zhang Jun , Shao Lina , Yan Rong , Wang Mingshan , Wang Jiafeng , Tu Yuexing , Ge Minghua
Published: September 2023

LINKED CONTENT

This article is linked to Huang et al and Packer and Bangash papers. To view these articles, visit https://doi.org/10.1111/apt.15962 and https://doi.org/10.1111/apt.16014
Editorial: outcome prediction in patients with cirrhosis and acute‐on‐chronic liver failure—authors' reply
Authors: Bernsmeier Christine , McPhail Mark J. W.
Published: September 2023

LINKED CONTENT

This article is linked to Bernsmeier et al and Alexopoulou and Vasilieva papers. To view these articles, visit https://doi.org/10.1111/apt.15932 and https://doi.org/10.1111/apt.16019
Letter: severe COVID‐19 infection and biologic therapies—a cohort study of 7808 patients in France. Authors' reply
Authors: Taxonera Carlos , Alba Cristina
Published: September 2023

LINKED CONTENT

This article is linked to Taxonera et al and Bataille et al papers. To view these articles, visit https://doi.org/10.1111/apt.15804 and https://doi.org/10.1111/apt.16040
Editorial: tenofovir alafenamide fumarate—a new silver bullet to prevent mother‐to‐child transmission of hepatitis B virus
Authors: Gish Robert G. , Elmofti Yousif
Published: September 2023

LINKED CONTENT

This article is linked to Ding et al and Pan papers. To view these articles, visit https://doi.org/10.1111/apt.16043 and https://doi.org/10.1111/apt.16101
Pharmacodynamics and pharmacokinetics of DWP14012 (fexuprazan) in healthy subjects with different ethnicities
Authors: Hwang Jun Gi , Jeon Inseung , Park Sun Ae , Lee Areum , Yu Kyung‐Sang , Jang In‐Jin , Lee SeungHwan
Published: September 2023

Background

DWP14012 (fexuprazan), a novel potassium‐competitive acid blocker, is under development for the treatment of acid‐related disorders.

Aims

To compare the pharmacodynamics (PDs), pharmacokinetics (PKs) and safety of DWP14012 among healthy subjects of Korean, Caucasian and Japanese descent.

Methods

A randomised, double‐blind, placebo‐controlled, single‐ and multiple‐dose study was conducted. Ten subjects in each dose group (40, 60 or 80 mg for Koreans; 40 or 80 mg for Caucasians; 20, 40 or 80 mg for Japanese) were randomly assigned to DWP14012 or a placebo. Twenty‐four‐hour intragastric pH measurements and serial blood samples were collected for PK/PD evaluation. The PK/PD parameters were compared between each ethnicity.

Results

The extent of gastric acid suppression was similar among the ethnicities; the mean percentages of time that the intragastric pH was above 4 after multiple doses of 40 mg in the Korean, Caucasian and Japanese subjects were 64.3%, 62.8% and 70.3%, respectively, and the corresponding values for the 80 mg dose were 94.8%, 90.6% and 90.6% respectively. The changes in serum gastrin were not clinically significant between all three ethnicities. The systemic exposure of DWP14012 was similar between the three ethnicities after the 40 mg doses but slightly lower in Caucasian and Japanese subjects after the 80 mg doses. Gastric acid suppression by DWP14012 showed a clear exposure‐response relationship in the three ethnicities.

Conclusions

Gastric acid suppression by DWP14012 was similar among the Korean, Caucasian and Japanese subjects in this study, and the PK, PK‐PD relationships and safety were also similar among the three ethnicities. DWP14012 could be used without consideration of ethnicity.
Communicating the risks of handling bats: analysing approaches used by Australian stakeholders in the context of Australian bat lyssavirus
Authors: Liang BP , Wingett K , Bosward KL , Taylor MR
Published: September 2023

Australian bat lyssavirus (ABLV) is a member of the Lyssavirus genus of the Rhabdoviridae family and is found in Australian bat species. It is of public health concern because of the rabies‐like syndrome it causes in humans, resulting in government health and wildlife agencies using varied communication approaches to inform targeted audiences about zoonotic risks associated with handling bats. Despite these warnings, the number of reports of human‐bat interactions remains high. This paper details a survey conducted to analyse the approaches utilised by a range of stakeholders to educate and communicate warnings to their target audiences. The survey focused on identifying the target audiences, communication methods used, along with the message frequency, content, and perceived effectiveness. Analysis of the top three messages delivered by stakeholders revealed that over half were information‐focused messages and over a third, instruction‐focused. Stakeholders identified the need to balance messaging about bat handling risks with information regarding the vulnerable status of bats and their environmental significance. Whilst the most common and (perceived) effective method of communication was one‐on‐one discussions, it was also identified to be ineffective for targeting mass audiences leading stakeholders to recognise the need to adapt to more efficient means of communication. The outcomes of this study may be useful to improve risk communication strategies regarding ABLV in Australia.
Uniform versus discriminatory tariffs when competition mode is endogenous
Authors: Lee Ki‐Dong , Choi Kangsik
Published: September 2023

We examine the welfare implications of two tariff regimes when firms have a forward‐looking view on trade policy. Discriminatory tariffs lead to Cournot competition, whereas uniform tariffs lead to diverse competition modes. If exporters are identical in production costs, all the trading countries are better off under the uniform rather than discriminatory tariff regime, which suggests a possibility that countries reach an agreement on the most‐favored nation (MFN) as a preferred tariff regime. For asymmetric costs among exporters; however, the competition mode determined endogenously under the uniform tariffs does matter for the welfare comparison. If Cournot competition emerges, then each country's preference is consistent with conventional wisdom. That is, the importing country and high‐cost exporters prefer a discriminatory tariff while low‐cost exporters have a uniform tariff regime. However, if the uniform regime leads to either Bertrand or asymmetric competition mode, then the cost gap between exporters would be the determinant factor. Only when the cost gap is sufficiently small, the uniform tariff, required by the MFN clause of the World Trade Organization, can be beneficial to all trading countries.
Gender differences in cyberbullying tolerance, traditional bullying victimization and their associations with cyberbullying perpetration among Beijing adolescents
Authors: Wang Xiying , Gao Yutong , Chen Binli
Published: September 2023

Drawing upon survey data collected from 632 adolescents aged from 13 to 16 in two secondary schools in Beijing, this study examined the mediating role of traditional bullying victimization and tolerance of cyberbullying between gender and cyberbullying perpetration. The results showed that 6.8% of the adolescents in the study reported cyberbullying perpetration in the past year, while 6.0% of them were victims of cyberbullying. Boys reported higher rates and tolerance of cyberbullying perpetration than girls did. The results also suggested that tolerance of cyberbullying and traditional bullying victimization served as mediators between gender and the perpetration of cyberbullying. Social workers' practices in schools, focused on promoting gender equality, healthy masculinity and the prevention of bullying, are discussed.
Age and efficacy of remote ischemic conditioning in acute ischemic stroke
Authors: Cui Yu , Zhang Jing , Chen Hui‐Sheng
Published: September 2023

Aims

A post hoc analysis of RICAMIS trial to evaluate functional outcomes in relation to patient age.

Methods

Patients in RICAMIS were divided into six age groups. The primary outcome was excellent functional outcome at 90 days, defined as modified Rankin Scale (mRS) score of 0–1. Compared with patients receiving usual care alone, we investigated the association of remote ischemic conditioning (RIC) effect with functional outcomes in each group and the interaction between RIC effect and age.

Results

Of 1776 patients, 498 were assigned to <60 years, 326 to 60 to <65 years, 325 to 65 to <70 years, 278 to 70 to <75 years, 206 to 75 to <80 years, and 143 to ≥80 years. Higher proportions of primary outcome were found associated with RIC in <60 years group (72.6% vs. 64.8%; adjusted risk difference [RD], 6.8%; 95% CI, −1.6% to 15.1%; p = 0.11), 60 to <65 years group (70.7% vs. 67.1%; adjusted RD, 3.1%; 95% CI, −7.2% to 13.3%; p = 0.56), 65 to <70 years group (70.5% vs. 63.6%; adjusted RD, 3.5%; 95% CI, −6.8% to 13.8%; p = 0.51), 70 to <75 years group (59.7% vs. 54.9%; adjusted RD, 4.7%; 95% CI, −7.1% to 16.4%; p = 0.61), 75 to <80 years group (61.5% vs. 55.9%; adjusted RD, 5.7%; 95% CI, −7.8% to 19.1%; p = 0.41), and ≥ 80 years group (59.2% vs. 59.7%; adjusted RD, −2.6%; 95% CI, −18.8% to 13.5%; p = 0.75). No significant interaction between RIC effect and age was found among groups.

Conclusions

This is the first report that RIC effect may be attenuated with increasing age in patients with acute moderate ischemic stroke with respect to functional outcome.
Analysis of the phosphoproteome in human dental follicle cells during osteogenic differentiation
Authors: Morsczeck Christian , Pieles Oliver , Beck Hans‐Christian
Published: September 2023

Dental follicle cells (DFCs) are osteogenic progenitor cells and are well suited for molecular studies of differentiation of alveolar osteoblasts. A recent study examined the metabolism in DFCs during osteogenic differentiation and showed that energy metabolism is increased after 14 days of differentiation (mid phase). However, previous studies have examined proteomes at early (2 h, 24 h) or very late (28 days) stages of differentiation, but not during the phase of increased metabolic activity. In this study, we examined the phosphoproteome at the mid phase (14 days) of osteogenic differentiation. Analysis of DFC phosphoproteomes showed that during this phase of osteogenic differentiation, proteins that are part of signal transduction are significantly regulated. Proteins involved in the regulation of the cytoskeleton and apoptosis were also increased in expression. As osteogenic differentiation induced oxidative stress and apoptosis in DFCs, the oxidative stress defense protein, catalase, was also upregulated during osteogenic differentiation, which supports the biomineralization of DFCs. In summary, this study revealed that during the middle phase (14 days) of osteogenic differentiation, processes in DFCs related to the control of cell organization, apoptosis, and oxidative stress are regulated.
Shaping hope in everyday life: Experiences of veteran spouses with post‐deployment mental health issues
Authors: Goeree Nadine , Dekker Natashe Lemos , de Reuver Yvon , Haagen Joris F. G. , Vermetten Eric
Published: September 2023

While spouses of military veterans have not been directly exposed to threats during deployment, they often experience a substantial post‐deployment‐related health burden while living with and caring for a partner with deployment‐related mental health issues. Drawing from in‐depth interviews, this study examined how female spouses of military veterans deal with the psychosocial effects of deployment. We show how these women cope. They keep their family lives going by maintaining hope for the future. We argue that hope is a dynamic practice between reality and possibility, and different forms of hope co‐exist. These range from temporary formulations of present‐centered hope, and permanent hopes directed towards the future. We illustrate how spouses challenge discourses around curative futures and adjust their hopes to maintain a more satisfactory everyday life and a positive horizon towards the future.
Practice tips for managing challenges in parenting capacity assessments in child protection court
Authors: Smith Krissie Fernandez , O'Donnell Phillip C.
Published: September 2023

Courts frequently rely on parenting capacity assessments to make decisions about visitation and case progress in child protection court. Although these evaluations can provide valuable information to courts, they often involve assessing areas of human behavior that are not clearly defined in the literature. For example, mental health professionals are often tasked with identifying risk and protective factors for child maltreatment while identifying factors that can impede progress towards reunification. Although some of these factors may be easy to identify and assess (e.g., symptoms of mental illness or substance abuse), others may be more challenging. For example, factors such as denial and minimization about risk factors and maltreatment, a parent(s)’ ability to protect their child(ren) from future incidents of maltreatment, the parent(s)’ potential for change, and the consideration of what is in the best interest of the child are hard to assess. This article will provide a summary of the research in these areas, provide tips for managing these areas, and highlight directions for future investigation that will help inform parenting capacity assessments in child protection court.
Evaluation of a protocol to assess a novel artificial biofilm equivalent for dentures—A prospective clinical pilot study
Authors: Kresse‐Walczak Katarzyna , Meissner Heike , Mauer René , Trips Evelyn , Boening Klaus
Published: September 2023

Objectives

This pilot study aimed to carry out preliminary tests of the removability of an artificial biofilm equivalent (ABE) and to verify the reproducibility of the ABE testing protocol for a planned main study.

Background

There is a lack of data to develop suitable artificial biofilm substitutes, which may be helpful to perform denture hygiene education and to carry out in vitro examinations of oral hygiene products.

Materials and Methods

This single‐group, prospective, longitudinal, interventional pilot study was conducted in Dresden (Germany) from February until December 2020. Participants were recruited who wore fully functional upper complete dentures. Denture biofilm was grown on acrylic specimens by wearing dentures for 12 h and 36 h using intraoral appliances. Acrylic specimens were coated with ABEs of three compositions: chitosan (ChS) 0.3 g, methylcellulose (MC) 1.7 g; ChS 0.2 g, MC 1.8 g; ChS 0.1 g, MC 1.9 g (labelled 1.7MC, 1.8MC and 1.9MC, respectively). All specimens underwent standardised mechanical brushing. The percentages of remaining biofilm (POB) were measured.

Results

Thirty‐one participants were prescreened, and eight (26%) were included. The appliances were well tolerated, and biofilm was collected. ABE was prepared and brushed as planned. Three and six brushing strokes were needed to remove 12‐h and 36‐h natural denture biofilm, respectively. Correspondingly, three brushing strokes were needed to remove 1.9MC ABE and six brushing strokes to remove 1.8MC and 1.7MC ABE. A reproducibility of ABE removal was indicated.

Conclusion

The removability of ABE and the ABE testing protocol were feasible and reproducible for conducting the future main study.
Cosmopolitan pathways from the Global South: How non‐middle‐class students become desirable Fulbright applicants
Authors: You Shunan
Published: September 2023

International student mobility (ISM) is largely interpreted as a global middle‐class capital accumulation strategy. Cosmopolitanism, which is the named outcome and effect of these mobile forms of social and cultural capital, is therefore disproportionately available to already privileged students. This study moves beyond this prevailing interpretation by examining how students from working‐ or lower‐middle‐class families with limited resources in Global South countries combine bottom‐up cosmopolitanism with educational mobility to get selected into highly competitive spaces, such as the Fulbright Foreign Student Program, the most prestigious educational and cultural program in the United States. Based on 20 in‐depth interviews with successful Fulbright applicants and participant observation, my findings suggest that working‐ and lower‐middle‐class applicants are largely successful because of their cosmopolitan dispositions which they cultivate in creative and agentive ways. This article adds texture and complexity to existing discussions on middle‐class hegemony in ISM and cosmopolitan subject‐making.
Helicobacter pylori infection reduces the efficacy of cancer immunotherapy: A systematic review and meta‐analysis
Authors: Gong Xiaomin , Shen Liting , Xie Jinliang , Liu Dingwei , Xie Yong , Liu Dongsheng
Published: September 2023

Background

Cancer immunotherapy has shown promising results in several tumors, but its efficacy is influenced by the immune state of the body. Helicobacter pylori (H. pylori) infection can modulate the immune function of the body through various pathways, ultimately affecting the effectiveness of cancer immunotherapy.

Aim

In this meta‐analysis, we aimed to explore the association between H. pylori infection and the efficacy of cancer immunotherapy.

Methods

We conducted a comprehensive search of PubMed, Embase, Web of Science, and Cochrane Central Register of Controlled Trials to identify relevant articles. We extracted and pooled the hazard ratio (HR) of the overall survival (OS) and progression‐free survival (PFS) by Review Manager 5.4.

Results

Our analysis included four studies with a total of 263 participants. Compared to the control group, patients receiving cancer immunotherapy with H. pylori infection had a shorter OS (HR = 2.68, 95% CI: 2.00–4.11, p < 0.00001) and PFS (HR = 2.25, 95% CI: 1.66–3.60, p < 0.00001).

Conclusion

Our meta‐analysis suggested that H. pylori infection has a detrimental effect on cancer immunotherapy.
Should supragingival scaling be performed separately prior to subgingival scaling and root planning in nonsurgical periodontal therapy? A systematic review of randomized trials
Authors: Oliveira Leandro Machado , de Oliveira Cícero Anghinoni , Angst Patrícia Daniela Melchiors , Antoniazzi Raquel Pippi , Zanatta Fabrício Batistin
Published: September 2023

Objective

To systematically evaluate randomized controlled trials (RCTs), with at least 6 months of follow‐up, on whether professional mechanical plaque removal (PMPR) including supragingival scaling should be performed prior and separately from subgingival scaling and root planning (SRP) in nonsurgical periodontal therapy (NSPT), in terms of clinical and patient‐reported outcomes (PROs) (CRD42020219759).

Methods

The MEDLINE, EMBASE, CENTRAL, LILACS and Web of Science electronic databases, as well as grey literature sources, were searched by two independent reviewers up to May 2023. The Cochrane Collaboration's Risk of Bias tool (RoB 2.0) was used for quality appraisal and GRADE for assessing the certainty of evidence. Random‐effects pairwise meta‐analyses compared the changes in probing pocket depth (PPD), clinical attachment loss (CAL), and bleeding on probing (BoP) of a stepwise NSPT approach (PMPR prior and separately from SRP) and conventional one‐step NSPT through mean differences (MDs) and associated confidence intervals (95% CI).

Results

Two RCTs were included, including data of 77 participants with severe periodontitis. One RCT presents high risk of bias and the other has some concerns. No significant differences were found between the stepwise approach and performing both steps simultaneously for any clinical outcomes, with overall very low certainty on evidence. No adverse effects were detected and there was no data on PROs.

Conclusions

There is very‐low certainty evidence of no significant difference on PPD and BoP reductions and CAL gain between supragingival scaling performed prior and separately from SRP and conventional one‐step NSPT.
Characterization and magnetic properties of CoFe2O4 nanoparticles synthesized by the co‐precipitation method
Authors: Bayça Feray
Published: September 2023

In this study, the characterization and magnetic properties of CoFe2O4 nanoparticles synthesized by co‐precipitation method were investigated. The calcined products obtained were characterized by X‐ray diffraction (XRD), scanning electron microscopy (SEM), energy dispersive X‐ray (EDAX), Fourier transformed infrared (FTIR) spectroscopy, and vibrating sample magnetometer. Crystallite size and phase composition were analyzed by X‐ray diffraction. Crystallite size and phase composition were analyzed by X‐ray diffraction. The average crystallite size of CoFe2O4 nanoparticles increased in the range of 15.85–32.14 nm with an increase in temperature from 500 to 700°C. It was observed that spherical CoFe2O4 nanoparticles were produced. Synthesis of CoFe2O4 nanoparticles was confirmed using XRD, SEM‐EDAX, and FTIR analyses. The effect of crystallite size, calcination temperature, and lattice parameter on saturation magnetization, remanent magnetization, coercivity, and magnetocrystalline anisotropy were investigated by vibrating sample magnetometer. As the crystallite size value increased, magnetocrystalline anisotropy also increased.
Low‐cost porous thermal insulation materials with tunable pore structures derived from fly ash by foam‐gelcasting
Authors: Li Minghui , Gao Qingqing , He Qun , Li Saisai , Quan Yuxin , Wu Mengfei , Li Chanhua
Published: September 2023

In order to adjust the pore structures and improve the thermal insulation property and mechanical strength of fly ash‐based insulation materials prepared by a foaming gel‐casting technique, the rheological behaviors of foaming slurries were adjusted. Furthermore, the effects of heating temperatures on the properties and microstructure of the insulation materials were investigated. The results showed that as the content of the dispersant increased, the viscosity of slurries increased first and then decreased. When the content of the dispersant reached 0.2 wt.%, the slurries showed excellent flow ability, which caused a lot of big pores to generate in the matrix. Moreover, the thickening agent, binder and solid content had a great influence on the thixotropy of the slurries. As the content of the thickening agent and binder were 0.25 wt % and 5.0 wt.%, respectively, the slurries with 45 wt.% solid content exhibited outstanding thixotropy, which was beneficial to improve the stability of generated closed pores. After treating at 1300°C for 2 h, the bulk density, compressive strengths, and thermal conductivity of the insulation materials prepared using the optimized slurries were 0.44 g cm−3, 3.27 MPa, and 0.13 W·m−1·K−1, respectively.
Neocapsular reconstruction for challenging partial nephrectomy: A feasibility study in a porcine model and recent clinical experience
Authors: Yasuda Yosuke , Attawettayanon Worapat , Nguyen Jane K. , Kattar Jackie , Lachowski Mary , Voros George , Kazama Akira , Campbell Rebecca A. , Krishnamurthi Venkatesh , Eltemamy Mohamad , Campbell Steven C.
Published: September 2023

Objectives

Multifocal renal masses and large central‐endophytic tumors can be challenging for partial nephrectomy (PN) due to the paucity of capsule remaining after tumor removal. Our objective was to develop a neocapsule to provide tamponade and test its feasibility/safety in a porcine model.

Methods

Eight live pigs (50–70 kg) underwent unclamped open right flank PN. Renal defects were 1 cm deep and had moderate ongoing venous bleeding. A 6 × 9 inch sheet of Nu‐knit® was used for neocapsular reconstruction with Fibrillar™ packing to provide modest tamponade and preclude ongoing bleeding. Blood chemistry and hemoglobin (Hb) levels were drawn preoperatively and postoperative Days 3/5/8. On postoperative Day 8, euthanasia was performed, and both kidneys were inspected and analyzed for histologic changes.

Results

PN defects ranged from 1 × 1 × 1 cm to 4 × 2 × 1 cm; four pigs had PN performed in both poles and four in one pole. Neocapsular reconstruction was successful (n = 8), with no perioperative complications. Median baseline Hb was 10.4 g/dL, and median Hb postoperative Days 3/5/8 were 10.0/10.8/10.6 g/dL, respectively. Median baseline serum creatinine (SCr) was 1.9 mg/dL, and median SCr postoperative Days 3/5/8 were 1.5/1.4/1.5 mg/dL, respectively. At sacrifice, no significant hematomas were observed. Other than adjacent to the PN site, there were no significant histologic changes in the parenchyma for operative kidneys versus controls. Based on our experience, we recently performed neocapsular reconstruction safely/effectively after extensive PN for multifocal tumors and for an allograft with difficult‐to‐manage subcapsular hematoma.

Conclusions

Neocapsular reconstruction after PN or capsular trauma appears feasible and safe and may be considered to reduce the risk of perioperative bleeding. However, further study will be needed to confirm the utility/efficacy of this approach.
Consumer‐oriented intelligent ripening control system for post‐ripening fruit
Authors: Li Yuliang , Huang Wentao , Li Hanyu , Wang Xiang , Zhang Xiaoshuan
Published: September 2023

To address the issues commonly encountered in traditional fruit ripening processes, which include reliance on manual experience, low efficiency, single control parameter, and significant fluctuations, a new intelligent fruit ripening control system has been designed. This system is based on a mathematical modeling algorithm, which allows for more effective and precise control over the ripening process. To ensure that the ripe fruits are transported to the fruit processing center in a low ripeness state, the proposed system adopts a strategy of precise control of temperature and ethylene, as well as range control of other environmental parameters. The RSSA‐PID model is used for ethylene and temperature control, which has high smoothness, fast response time, and high stability. Compared with the traditional PID model, the RSSA‐PID model has better dynamic performance and stability. Finally, the proposed system is applied to the ripening process of post‐ripening fruits, and the results show that the system achieves intelligent ripening, precise control, and low power consumption. The temperature and ethylene concentration are controlled within a variation of no more than 0.5%, and the humidity, oxygen, and carbon dioxide are maintained within reasonable thresholds. Overall, this paper provides a promising solution for the ripening process of post‐ripening fruits, which can benefit the fruit industry by improving the efficiency and quality of the supply chain.

Practical Application

The ripening chamber environment is a dynamic equilibrium environment with non‐linear characteristics because the fruits in the ripening chamber are constantly exchanging substances and energy with the environment through respiration and transpiration. An intelligent ripening control system (IRCS) for post‐ripening fruits is proposed in this paper (Figure 1). The whole ripening process runs automatically, which significantly reduces the ripening time and saves a lot of post‐processing time. The shorter ripening time combined with the latest intelligent software and hardware means that only as much energy as is actually needed is consumed. If the sales market changes, the fruit can be stored under air conditioning (CA) until the scheduled delivery date without significant further ripening and losses and complaints can be minimized.
The economic constitution and the political constitution: seeking the common good in the post‐national setting
Authors: EVERSON MICHELLE
Published: September 2023

In the post‐national setting, the concept of the ‘economic constitution’ has been seen as design template and saviour; whether based on transactional certitude or founded on ordoliberal precepts, the economic constitution is assumed to legitimate economic integration across national borders in the absence of comprehensive political settlement. Nevertheless, recent tensions – not only within the European Union (EU) but also, more strikingly, within the World Trade Organization context – indicate the limits of economic constitutionalism. This article seeks to identify the roots of recent dysfunction within the history and theory of economic constitutionalism. It traces the evolution of an adjudicational economic constitutionalism and its place within the EU legal order, including the new EU Charter of Fundamental Rights, and contrasts this vision with the more comprehensive and/or socialized models of economic constitutionalism found not only within the Weimar Republic but also within the post‐revolutionary/post‐conflict constitutional context. The article also places a major emphasis on theorizing around the apex of economic‐constitutional thought, ordoliberalism, but concludes that no concept of the economic constitution can be seen in isolation from its social‐political context, or from notions of the common good. To this exact degree, failures in modern economic constitutionalism may derive from a misplaced universalism – a technocratic absolutism that abdicates political responsibility for the common good, locating it instead in an ‘idolatry of the factual’ or a new naturalism of market inevitability.
Already Gone: Retaining Women in State Legislatures
Authors: Butcher Jordan , Haynes Noah
Published: September 2023

Diversity in representation is a necessary component of legislatures, both normatively and for the best policy outcomes. Recently, women legislators have received more attention, as has their role in office. While scholars have examined the importance of recruiting more women to office, there is less emphasis on the retention of women as legislators. The key to expanding women's representation in state legislatures rests in both the recruitment and retention of women. We theorize that variation in institutional and personal support affects whether women choose to stay in the state legislature long term. To test this, we examine the turnover rates for women from all 50 US states to identify the barriers to service and how to mitigate them. Our analysis contributes an understanding of how to create a more supportive environment to aid the retention of women in office and speaks to institutional capacity and performance in the workplace.
Understanding the pathway between work and health outcomes for women during the preconception, pregnancy, and postpartum periods through the framing of maternal obesity
Authors: Madden Seonad K. , Ahuja Kiran D. K. , Blewitt Claire , Hill Briony , Hills Andrew P. , Skouteris Helen
Published: September 2023

The link between work and health outcomes for preconception, pregnant, and postpartum (PPP) working women is complex. Further, innovation and enhanced understanding are required to address the work‐related determinants of maternal obesity. However, workplace health promotion is not typically systems‐based nor attuned to the specific needs and context of individual PPP women. We propose that to improve health outcomes for PPP women, we must understand the pathways between paid work and health for the individual woman by taking a systems‐thinking approach. In this paper, we (a) outline the rationale for why the oversimplification or “dilution” of individual context may occur; (b) present a systems‐informed pathway model (the “Context‐Exposure‐Response” Model) and overview of potential work‐related impacts on health and wellbeing outcomes for PPP women using maternal obesity to provide context examples; (c) further investigate the role of motivational factors from a systems perspective; and (d) briefly examine the implications for policy, practice, and intervention design. It is anticipated that this research may act as a starting point to assist program developers, researchers, and policymakers to adopt a systems‐focused perspective while contributing to the health improvement and obesity prevention of PPP women.
The reestablishment of mangrove crabs (Scylla spp.) in an abandoned pond following natural mangrove recolonization
Authors: Lebata‐Ramos Ma. Junemie Hazel , Solis Ellen Flor D. , Sibonga Rema C.
Published: September 2023

Scylla spp. are among the most economically important fisheries resources derived from the mangroves. However, the widespread mangrove destruction resulted in the loss of habitat, thus the dwindling capture production of many mangrove‐associated faunas. Although studies have shown that Scylla populations have reestablished in mangrove‐reforested areas, this study was the first in a mangrove‐recolonized abandoned pond in the Philippines. Six fishers conducted standardized fishing every spring tide of the month using cylindrical bamboo traps. All crabs caught from July 2010 to December 2011 were recorded for species, sex, sexual maturation of females, carapace width (CW), and body weight (BW). Total landings comprised 14,262 crabs weighing 1,743 kg; 79.67% Scylla olivacea, 20.18% S. tranquebarica, and 0.15% S. serrata. CW ranged 3.1–17.1 cm and BW 10–1,250 g, with the male crabs comprising 39.23–64.65% of the monthly landings and the females distributed as 19.88–45.01% immature, 0.50–16.57% mature, 0.45–16.02% gravid, and less than 0.10% spent crabs. Monthly landings ranged 254–1,231 pcs of crabs or 32.38–160.59 kg. The monthly mean catch per unit effort (CPUE), in terms of number, was 0.101 ± 0.01–0.456 ± 0.02 crab gear−1 day−1 (max = 1.13), while in terms of biomass, 12.86 ± 0.84–54.36 ± 3.16 g gear−1 day−1 (max = 112.50). Length–weight relationships of S. olivacea and S. tranquebarica are expressed as W = 0.224967L2.9864 (r2 = 94.08%, p < 0.001; n = 11,363) and W = 0.173409L3.1074 (r2 = 92.71%, p < 0.001; n = 2,878), respectively. This study revealed that Scylla spp. could reestablish in mangrove‐recolonized abandoned ponds.
Reframing the transboundary water discourse: Contextualized international law in practice
Authors: Wouters Patricia , Vinogradov Sergei
Published: September 2023

Can international law provide new insights for better understanding transboundary water practice? Selecting China as one of the most challenging case studies, the article explores the possible elements of a reconceptualized approach to international freshwater management. This study demonstrates how the legal discourse surrounding regional transboundary waters can be reframed using the concept of contextualized international law to offer increased opportunities for improved transboundary water cooperation.
State responsibility in international law for transboundary water‐related harm: The emergence of a new ecosystems‐based paradigm?
Authors: McIntyre Owen
Published: September 2023

Though one might reasonably expect that transboundary harm caused to the riparian interests of watercourse States should quite easily give rise to findings of legal responsibility on the part of the State causing such harm, this has rarely been the case. One reason commonly advanced is that the primary rules of international water law, breach of which would give rise to State responsibility, are vague and uncertain as regards their precise normative implications. However, recent developments regarding the requirement to protect riverine ecosystems and to maintain related ecosystem services provide an important degree of clarity as regards the standard of conduct expected of watercourse States, and the types of harm which may be compensable. This is welcome considering the important role that State responsibility might be presumed to play in giving effect to the values and commitments enshrined in the rules and principles of international water law.
Beyond semantics: Overcoming the normative incoherence surrounding the protection of international watercourse ecosystems
Authors: Liu Yang
Published: September 2023

Protecting and preserving the ecosystems of international watercourses requires a coherent normative framework. Problems can arise where inconsistent terms are used to define and describe these shared resources. This leads to possible normative incoherence around the duties to protect and preserve ecosystems. At the heart of the matter are the diverse definitions used for shared freshwaters and international ecosystems. In many cases, there is a ‘terrestrial gap’—the geographical space created by the terms used to describe ‘international watercourse’ on the one hand, and ‘ecosystem’ on the other. More often than not, the former is defined in narrow geographical terms, while the latter is more broadly cast, to include related terrestrial elements. This article explores how the potential normative incoherence related to the protection and preservation of the ecosystems of an international watercourse might be overcome through three approaches, which are explored in treaty practice across the field.
Smart or smash? The effect of financial sanctions on trade in goods and services
Authors: Besedeš Tibor , Goldbach Stefan , Nitsch Volker
Published: September 2023

We examine the extent to which financial sanctions imposed by Germany through its European Union and United Nations commitments cause collateral damage on Germany's trade in goods and services. Financial sanctions reduce Germany's inflows and outflows of financial assets, as well as imports and exports of goods and services. The relative effects on trade in goods and services are weaker than on financial assets, about half as large in the case of goods and two‐thirds as large in the case of services. The effect on trade in goods is entirely due to episodes where financial sanctions are accompanied by export restrictions of specific goods. In the case of services trade, only exports are affected by financial sanctions once export restrictions are considered. The primary channel through which sanctions affect the three types of cross‐border flows is the extensive margin. Anticipation effects are quite strong for financial assets and weak for services and goods.
Evaluation of pulmonary abnormalities in recipients of hematopoietic cell transplants and cellular therapies
Authors: Thomas Lora , Boatman Julie
Published: September 2023

Hematopoietic cell transplant (HCT) and chimeric antigen receptor T‐cell (CAR‐T) therapy recipients are susceptible to multiple pulmonary complications that are caused by infectious and noninfectious processes. Numerous variables can be associated with specific pulmonary diseases including time from transplantation, presence of graft versus host disease (GVHD), underlying disease, and prolonged neutropenia and lymphocytopenia. Most pulmonary complications are infectious in origin, with bacterial pneumonia remaining the most common pulmonary infection, particularly before neutrophil engraftment. Invasive fungal infections continue to affect this patient population even when antifungal prophylaxis is used. Noninfectious pulmonary complications include a wide differential of pathologies in this population, and as clinical presentations of these various pulmonary disorders often overlap, clinicians frequently will use a multidisciplinary approach in diagnosing these abnormalities. Radiography, particularly with chest computed tomography (CT) imaging, is an essential tool in identifying pulmonary pathology and potential sources. While standard microbiological cultures of respiratory specimens are still utilized, their role is limited by low sensitivity and diagnostic yield. The likelihood of obtaining a diagnosis can be improved by using other microbiological assays, including fungal antigen tests and molecular diagnostic methods, particularly if specimens are collected via bronchoscopy. This review will highlight the more common causes of pulmonary diseases encountered after HCT and CAR‐T and will examine the different methods in their diagnosis.
Evidence that donors with variant RH genotypes are associated with unexpected Rh antibodies
Authors: Kirkegaard Julie , Rahorst Lynsi , Burgos Anna , Music Aplenc Lejla , Iqbal Nazia Tabassum , Vege Sunitha , Francis Christine Lomas , Westhoff Connie M.
Published: September 2023

Background

We previously reported unexpected Rh antibodies in the plasma of patients with sickle cell disease (SCD) that demonstrated common Rh specificities in the absence of transfusion of RBCs positive for that antigen. We hypothesize that these antibodies might result from transfusion of antigen‐negative donor units with variant RH genotypes.

Methods

Plasma testing by tube and IgG gel, extended RBC phenotyping, and HEA and RH genotyping were by standard methods.

Case

A 6‐year‐old female with SCD, phenotype D + C‐c + E–e + K‐ undergoing exchange transfusion with CEK‐ and Fy(a‐) units, presented with anti‐C in the plasma, a + DAT and warm autoantibody (WAA) in the eluate. Her RH genotype was unremarkable: RHD*D/DAU0 and RHCE*ce/ce(48C). Units (n = 10) transfused over the prior 6 months were confirmed CEK‐ by serology and DNA testing. Most (n = 7) were Rh‐negative. A unit with variant RH, RHD*DIIIa/weak partial 4.0, RHCE*ceVS.03/ceVS.02, was transfused 5 weeks prior. Anti‐C and + DAT continued to demonstrate for 25 weeks. Total hemoglobin and % Hgb S did not deviate from her established baseline.

Conclusion

We show direct association of plasma anti‐C with transfusion of a C‐negative unit with variant RH encoding partial D and uncommon V/VS+ hrB– phenotype. The antibody was transient, without evidence of compromised survival of transfused RBCs. The +DAT and WAA complicated workups and selection of units, and it is uncertain whether donors of the same genotype should be avoided. Minority donors are important for CEK‐matching to avoid depleting Rh‐negative supplies. Consideration of patient and donor RH genotypes may avoid unexpected antibodies and improve allocation of rare donations.
Discussion: “A Numerical Scheme for Fractional Mixed Convection Flow Over Flat and Oscillatory Plates” (Yasir Nawaz, Muhammad Shoaib Arif, Kamaleldin Abodayeh, 2022, ASME J. Comput. Nonlinear Dyn., 17(7), p. 071008)
Authors: Pantokratoras Asterios
Published: September 2023

Some serious errors exist in the above paper.
On the Inverse Problem of Time-Dependent Coefficient in a Time Fractional Diffusion Problem by Newly Defined Monic Laquerre Wavelets
Authors: Bayrak Mine A. , Demir Ali
Published: September 2023

The primary aim of this research is to establish the time-dependent diffusion coefficient in a one-dimensional time fractional diffusion equation in Caputo sense by means of newly defined Monic Laquerre wavelets (MLW) and collocation points. We first give the definition of MLW by taking Monic Laquerre's polynomials into account. Later, time fractional diffusion problem is reduced into a system of ordinary fractional and algebraic equations by utilizing MLW. The residual power series method (RPSM) and the overdetermined data are applied to this system to determine the solution and the unknown time-dependent coefficient together in series form. In the end, illustrative examples are presented to show the stability and accuracy of the proposed wavelet method for the inverse problem of determining unknown time-dependent coefficient in fractional diffusion problems. The reliability of the proposed algorithm for the inverse problems is supported by high degree of accuracy in the given examples.
Bifurcation Analysis of Driver's Characteristics in Car-Following Model
Authors: Yadav Sunita , Redhu Poonam
Published: September 2023

According to traffic flow theory, traffic is affected not only by road conditions such as bottlenecks, the environment, interruptions, and so on but also by the driver's behavior. To control and manage increasingly complex traffic networks, it also becomes necessary to study the effects of driver characteristics significantly. In this research, a novel car-following model is proposed which considers both the driver's cautious and aggressive instincts for optimal and relative velocity integrals. To analyze the stability of the new model, a small perturbation method was used. Further, the modified Korteweg–de-Vries equations were established with the help of a reductive perturbation method. In bifurcation analysis, we examine the existence and stability of Hopf bifurcation in various systems. This helps to gain deeper insight into the behavior of these dynamical systems and can be used to develop more efficient control strategies. Numerical simulations and theoretical analyses both show that the aspects of the enhanced model related to driver characteristics have a major affect on traffic flow stability. Additionally, the model can adeptly handle traffic congestion and quickly return to its normal state if any disruption occurs.