bluuebunny/crossref_metadata_2025 huggingface dataset:
Development and Validation of an Algorithm Model for Predicting Heat Sink
Effects during Pulmonary Thermal Ablation
Authors: Du Peng , Chen Zenan , Yuwen Chang , Meng Liangliang , Feng Wei , Ge Zongyuan , Zhang Xiao , Xiao Yueyong
Published: November 2023

Aims:

The aim of this study was to develop an algorithm model to predict the heat sink effect during thermal ablation of lung tumors and to assist doctors in the formulation and adjustment of surgical protocols.

Background:

The heat sink effect is an important factor affecting the therapeutic effect of tumor thermal ablation. At present, there is no algorithm model to predict the intraoperative heat sink effect automatically, which needs to be measured manually, which lacks accuracy and consumes time.

Objective:

To construct a segmentation model based on convolutional neural network, it can automatically identify and segment pulmonary nodule and vascular structure, and measure the distance between nodule and vascular.

Methods:

First, the classical Faster RCNN model was used as the nodule detection network. After obtaining the bounding box of pulmonary nodules, the VSPP-NET model was used to segment nodules in the bounding box. The distance from the nodule to the vasculature was measured after the surrounding vasculature was segmented by the VSPP-NET model. The lung CT images of 392 patients with pulmonary nodules were used as the training data of the algorithm. Sixty-eight cases were used as algorithm validation data, 29 as nodule algorithm test data, and 80 as vascular algorithm test data. We compared the heat sink effect of 29 cases of data with the results of the algorithm model and expert segmentation and compared the difference between the two results.

Results:

In pulmonary CT image vasculature segmentation, the recall and precision of the algorithm model reached >0.88 and >0.78, respectively. The average time for automatic segmentation of each image model is 29 seconds, and the average time for manual segmentation is 158 seconds. The output image of the model shows that the results of nodule segmentation and nodule distance measurement are satisfactory. In terms of heat sink effect prediction, the positive rate of the algorithm group was 28.3% and that of the expert group was 32.1%, with no significant difference between the two groups (p=0.687).

Conclusion:

The algorithm model developed in this study shows good performance in predicting the heat sink effect during pulmonary thermal ablation. It can improve the speed and accuracy of nodule and vessel segmentation, save ablation planning time, reduce the interference of human factors, and provide more reference information for surgeons to make ablation plans to improve the ablation effect.
Chemistry, Biological Properties, and Bio-analysis of Tafamidis, a New
Transthyretin Stabilizer: A Systematic Review
Authors: Agarwal Nikhil , Sharma Sanjay , Sultan Jasira
Published: November 2023

Background:

Cardiomyopathy is a global health crisis that affects people all over the
world. Consequently, scientists felt compelled to look for and develop ever-more-powerful
pharmaceuticals. For ATTR-CM, the only drug currently recommended by the European Society
of Cardiology is Tafamidis.

Objectives:

The primary aim of this review article is to understand the chemistry, pharmacodynamic,
pharmacokinetic, and bio-analytical methods available for Tafamidis.

Methods:

A systematic review of the existing resources was accomplished up to 2022, comprising
existing studies forming the database covering the existing resources from Web of Science,
ScienceDirect, and PubMed.

Results:

The review was based on a systematic review of all the existing studies used to formulate
the database. The study also illustrated the PRISMA design that systematically analyses the
prevalent resources.

Conclusion:

Minimal analytical techniques are observed for quantifying the Tafamidis and
transthyretin kinetic stabiliser. Therapeutic, pharmacological, and analytical considerations for
the novel drug Tafamidis are discussed in this review. Particular attention is paid to the many
different analytical and bioanalytical methods currently available for estimating Tafamidis, and
the need is highlighted to develop a straightforward, validated technique that meets green chemistry
standards.
Irrigation Scheduling of Pawale Project using FAO-CROPWAT 8.0
Authors: Somani Pooja , Charhate Shrikant , Garudkar Avinash
Published: November 2023

Introduction:

The application of irrigation water to various crops in the command area
based on daily crop water requirements considering the water holding capacity of different
irrigated soils is a vital aspect of irrigation management. Considering the importance of irrigation
scheduling, the FAO CROPWAT 8.0 is a patent tool, as it gives crop water requirements and
irrigation schedules based on climatological and physiographic factors.

Method:

In this patent study, the CROPWAT 8.0 model is used to integrate the Cropwat model,
long-term climate data is used, soil sensitivity analysis is performed and crop-specific water need
is identified for the command area of the Pawale irrigation project which is a novelty as cropwat
is not used previously for the study area. Pawale irrigation project is located in the Thane district
of Maharashtra, India. Nineteen years of climatic data are used for the analysis, considering seven
crops to calculate the crop water and net irrigation requirement for the kharif and rabi seasons.

Result:

The result indicates that crop-wise and season-wise variation of crop water requirement is
from 2.5 to 1055.1 mm, and the net irrigation requirement for the year is 618.6 mm. It is also
observed that rice requires more water from the initial stage up to the development stage than
other crops considered in this study.

Conclusion:

In conclusion, we can say that the cropwat model with long-term climate data can
develop effective data for crop's specific water needs. The results indicate that evapotranspiration
has a greater impact on crop water and net irrigation requirements because, in both cases, the
increase or decrease of ETo will affect the crops and their water requirement. The sensitivity
analysis for different types of soils is also carried out for groundnut. The result indicates that,
apart from crops, soil water-holding capacity is essential for irrigation scheduling. It is seen that
nine rotations are required for red sandy soil as compared to six rotations and four rotations for
red sandy, loamy soil and black clay soil, respectively.
The Effect of Relationship Marketing on Customer Gratitude and Customer Loyalty at Farm to Table Business
Authors: Mekasari Firsta Koesdyah , Setiawan Budi , Isaskar Riyanti , Koestiono Djoko , Syafrial  , Maulidah Silvana
Published: November 2023

Farm to Table Business is one of the platform for selling agricultural products by digital marketing that really needs a relationship marketing strategy to add customers and increase customer loyalty by increasing customer gratitude. Relationship marketing is a form of strategy to retain customers. The purpose of this research is to analyze the effect of relationship marketing on customer gratitude and the effect of customer gratitude on customer loyalty at Farm to Table Business. This study used a purposive sampling technique to determine the sample with a total of 100 respondents. The data analysis technique in this study used SEM PLS (Partial Least Square) with Warp PLS 7.0 software. The results of this research show that: (1) Relationship marketing has a positive and highly significant effect on customer gratitude by 0.22; (2) Customer Gratitude has a positive and highly significant effect on customer loyalty by 0.56.
Participatory Communication to Strengthen Farmers' Empowerment and Adaptation in Facing the Impacts of Climate Change
Authors: Abdullah Said , Sarwoprasodjo Sarwititi , Hapsari Dwi Retno
Published: November 2023

Agriculture and farmers are sectors and parties affected by climate change. Unfortunately, farmers' knowledge and adaptive capacity are still low due to the limited climate change information that they receive. The development of communication models to strengthen the interaction and flow of information has been very active. However, it has not yet addressed the lack of empowerment and scarcity of farmer participation. Therefore, we need a dialogical, horizontal, participatory communication model with an emphasis on empowerment and farmer participation. This research, using a participatory communication model, aims to see how participatory communication can encourage the empowerment and adaptability of farmers to climate change. This study uses a participatory action research approach with participatory data collection techniques for the Rural Communications Assessment (PRCA). The theory used is participatory communication and social change, which allows farmers and researchers to be equally involved and dialogue to occur. This research demonstrates the fact that participatory communication through a dialogue process can promote common goals and action in dealing with climate change. In addition, this research was also able to increase farmer empowerment, which was marked by changes at the individual farmer and social levels. These changes take the form of strengthening farmers' knowledge, perceptions, and skills related to climate change and adaptation actions and increasing farmer participation in village development planning. Farmers have been able to push the issue of strengthening farmer resilience to become part of the village development plan.
Livelihood Resilience of Small Fishers Households in Rural Areas, Indonesia
Authors: Nissa' Zulfa Nur Auliatun , Nurmastiti Ardela , Setyowati Ratih , Mariyani Siti
Published: November 2023

The concept of livelihood resilience provides a unique framework for examining the utilization of livelihood capital and resilience values of farming households in ensuring sustainable communities. This study was conducted in Muarareja Village, Tegal Barat Subdistrict, Tegal City, in January-March 2019 by assessing the utilization of five livelihood capitals and livelihood resilience actions of fisher households facing social, economic, and ecological pressures. Data were collected through surveys, observations, and structured interviews, supported by a literature review. Purposive stratified-accidental sampling was used to interview fishermen from every socioeconomic class. The sample was 40 small-scale fisher households divided into 35 lower-layer fisher households and five upper-layer fisher households. Data analysis was conducted descriptively with simple tabulation to describe the condition of the study area. The results showed that social capital is the main capital utilized by lower-layer fishermen. Meanwhile, physical and financial capital are mostly utilized by upper-layer fisher households. Genealogical relationships and territorial ties in the study location make social capital dominant. Self-organization is the highest resilience action by lower-layer fisher households by prioritizing the value of trust. Meanwhile, upper-layer fishermen households have a high resilience value in the capacity of learning action on the value of experimentation. Ownership of larger production capital makes it easier for upper-layer fishermen households to make many alternatives to continue fishing. Meanwhile, due to limited ownership and access to production capital, lower-layer fishing households prioritize the value of trust between neighbors and relatives as their social safety net.
Price Volatility of Horticulture Commodity During the Pandemic in East Java, Indonesia
Authors: Hartono Rachman , Rahman Moh. Shadiqur , Retnoningsih Dwi , Shaleh Mohammad Ilyas
Published: November 2023

In the past two years, market information and the distribution of agricultural products have been affected by the COVID-19 pandemic, which has limited the distribution of information and the movement of agricultural products. As a result, the COVID-19 pandemic can lead to non-competitive behavior among intermediary traders, especially those operating in concentrated markets. This research aims to analyze the price volatility of horticulture commodity during the pandemic in East Java, Indonesia. The research data was collected through the official website of the Information System for Availability and Price Development of Basic Necessities in East Java (SISKAPERBAPO). The method used to analyze the impact of COVID-19 on horticultural agricultural product prices is ARCH (Autoregressive Conditional Heteroscedastic) and GARCH (Generalized Autoregressive Conditional Heteroscedasticity). The volatility results show that the prices of chili and shallots often fluctuate with high and unpredictable variations. However, the fluctuations in the prices of these two commodities are not due to a lack of supply or high demand, but rather due to the characteristics of these commodities, which are perishable and highly dependent on the season of production. The lower the quality, the lower the price will be. The price of shallots is relatively stable compared to chili due to its longer shelf life and less depreciation. The constraint faced by farmers of these two commodities during harvest time is the lack of storage facilities to store their harvest, forcing them to sell all their produce to middlemen or traders, which is one of the causes of the fluctuation of commodity prices.
Industri Makanan Halal: Perbandingan Indonesia dan Malaysia
Authors:   Jember University, Fatonah Isti , Trihartono Agus ,   Jember University, Hara Abubakar Eby ,   Jember University
Published: November 2023

Penelitian ini bertujuan untuk mengeksplorasi dan membandingkan industri makanan halal Indonesia dan Malaysia. Industri makanan halal di kedua negara akan dibandingkan menggunakan tiga indikator yaitu sertifikasi halal, regulasi halal, serta strategi nation branding. Ketiga indikator ini akan di analisa menggunakan konsep good governance dan nation branding. Hasilnya, dalam sertifikasi halal, Indonesia dan Malaysia merupakan salah satu yang terbaik di dunia. Dalam hal regulasi halal, Malaysia memiliki regulasi yang sudah jelas sehingga memudahkan pihak luar yang ingin mendaftarkan kehalalalan produk mereka. Sementara itu, regulasi halal Indonesia masih kurang jelas. Dalam hal nation branding, Malaysia sudah mulai mengukuhkan posisinya di kancah dunia melalui branding ‘global halal hub’. Sementara Indonesia juga ingin mengikuti langkah branding yang sama. Indonesia dan Malaysia sama – sama negara mayoritas muslim. Dan ada indikasi justru hal ini malah memperlambat pertumbuhan industri halal.
The effects of action learning-based education of nursing students on the perception of child abuse
Authors: Ri Nam Hye , Park Sun Jung
Published: November 2023

The purpose of this study was to determine the impact of an integrated theoretical and practical educational approach on nursing students' understanding of children's rights and perceptions of child maltreatment, as well as their motivation and efficacy to learn. The study used a single-group pretest-posttest design to assess changes in perceptions following an action learning-based curriculum focused on child maltreatment in pediatric nursing education. Data from participating nursing students were analyzed using descriptive statistics, t-tests, and one-way ANOVA using SPSS 21.0. The results indicated a significant increase in the students' awareness of children's rights (t=-2.71, p=.008) and recognition of child abuse (t=-5.73, p<.001) following the intervention. This study underscores the effectiveness of action learning in cultivating a deeper understanding of child rights and abuse among nursing students, highlighting its potential as an educational strategy in nursing curricula.
Exploring Whether the Electronic Optimization of Routine Health Assessments Can Increase Testing for Sexually Transmitted Infections and Provider Acceptability at an Aboriginal Community Controlled Health Service: Mixed Methods Evaluation
Authors: McCormack Heather , Wand Handan , Newman Christy E , Bourne Christopher , Kennedy Catherine , Guy Rebecca
Published: November 2023

Background

In the context of a syphilis outbreak in neighboring states, a multifaceted systems change to increase testing for sexually transmitted infections (STIs) among young Aboriginal people aged 15 to 29 years was implemented at an Aboriginal Community Controlled Health Service (ACCHS) in New South Wales, Australia. The components included electronic medical record prompts and automated pathology test sets to increase STI testing in annual routine health assessments, the credentialing of nurses and Aboriginal health practitioners to conduct STI tests independently, pathology request forms presigned by a physician, and improved data reporting.

Objective

We aimed to determine whether the systems change increased the integration of STI testing into routine health assessments by clinicians between April 2019 and March 2020, the inclusion of syphilis tests in STI testing, and STI testing uptake overall. We also explored the understandings of factors contributing to the acceptability and normalization of the systems change among staff.

Methods

We used a mixed methods design to evaluate the effectiveness and acceptability of the systems change implemented in 2019. We calculated the annual proportion of health assessments that included tests for chlamydia, gonorrhea, and syphilis, as well as an internal control (blood glucose level). We conducted an interrupted time series analysis of quarterly proportions 24 months before and 12 months after the systems change and in-depth semistructured interviews with ACCHS staff using normalization process theory.

Results

Among 2461 patients, the annual proportion of health assessments that included any STI test increased from 16% (38/237) in the first year of the study period to 42.9% (94/219) after the implementation of the systems change. There was an immediate and large increase when the systems change occurred (coefficient=0.22; P=.003) with no decline for 12 months thereafter. The increase was greater for male individuals, with no change for the internal control. Qualitative data indicated that nurse- and Aboriginal health practitioner–led testing and presigned pathology forms proved more difficult to normalize than electronic prompts and shortcuts. The interviews identified that staff understood the modifications to have encouraged cultural change around the role of sexual health care in routine practice.

Conclusions

This study provides evidence for the first time that optimizing health assessments electronically is an effective and acceptable strategy to increase and sustain clinician integration and the completeness of STI testing among young Aboriginal people attending an ACCHS. Future strategies should focus on increasing the uptake of health assessments and promote whole-of-service engagement and accountability.
Integrating Text and Image Analysis: Exploring GPT-4V’s Capabilities in Advanced Radiological Applications Across Subspecialties (Preprint)
Authors: Busch Felix , Han Tianyu , Makowski Marcus R , Truhn Daniel , Bressem Keno K , Adams Lisa
Published: November 2023

UNSTRUCTURED

This study demonstrates that GPT-4V outperforms GPT-4 across radiology subspecialties in analyzing 207 cases with 1312 images from the Radiological Society of North America Case Collection.
Kegiatan knowledge sharing dalam meningkatkan literasi kesehatan ibu menyusui di AyahASI Indonesia
Authors: Anwar Rully Khairul , Mananohas Andy , Rachmawati Tine Silvana
Published: November 2023

Introduction. This research aims to identify and understand the sharing of knowledge in improving health literacy of breastfeeding mothers at AyahASI Indonesia.

Data Collection Methods. This research used a qualitative method with case study approach. Data collection techniques were carried out through observations, interviews and literature studies.

Data Analysis. Data analysis technique was conducted using the knowledge conversion theory. The stages of data analysis included description, reduction, and selection. Subject of this research is one founder and two followers.

Results and Discussion. Findings of this study explain that the knowledge sharing process at AyahASI Indonesia includes socialization, externalization, combination, and internalization. Results involve managers and followers in sharing knowledge either through direct communication such as gatherings or indirect communication such as using social media. Several obstacles faced were the use of language, scope of implementation, unethical milk marketing formulas, funds, and human resources.

Conclusion. Knowledge sharing activities at AyahASI Indonesia aims to improve health literacy of breastfeeding mothers in order to be successful in providing breast milk to children. Suggestions can be started by forming a more reliable management system, expanding members to areas that have not been reached, selective in choosing words and collaborating with more health workers.
Peran pustakawan di Perpustakaan Universitas Indonesia dalam upaya preservasi digital pada koleksi e-local content
Authors: Aulia Nabila , Tamara Adriani Salim
Published: November 2023

Introduction. Digital preservation is the process of maintaining collections in digital format to ensure access, usability, and long-term durability for users. This research aims to identify the role of librarians and library staff in carrying out digital preservation activities on e-local content collections at the Universitas Indonesia Library.

Data Collection Methods. The method used was qualitative research with a case study type. Data collection techniques were conducted through interviews, observations, and document study.

Data Analysis. The data analysis technique used was data reduction, data presentation, data validation, and conclusion drawing.

Results and Discussion. The role of librarian in the digital preservation of e-local content or UI-ana collections are collection preservation agents, guarantors of access to information, defenders of preservation policies, guardians of adaptation to technology, and leaders in networking between staff and managers. 

Conclusion. The role implemented by library staff is quite good. However, software and hardware updates are needed, and special policies can be made so that digital preservation of e-local content collections can run optimally.
Peluang berwirausaha sebagai librarypreneur di era teknologi informasi
Authors: Siti Rohaya  , F. Trisakti Haryadi  , Alia Bihrajihant Raya
Published: November 2023

Introduction. This study examines the business opportunities in the field of library and Information run by graduates of the Library Science program at UIN Sunan Kalijaga and UIN Syarif Hidayatullah.

Research methods. This research is a qualitative research with a case study approach. Data obtained through observation, interviews, and documentation. Determination of informants through snowball sampling while the analysis was carried out descriptively.

Results and Discussion. The development of Information Technology presents a wide range of business opportunities in the field of library and information. Entrepreneurship is a promising option for Library Science graduates. These efforts include library management, library automation; utilization of digital Technology; Information System Design; information consulting; training and teaching; software and hardware development; procurement of library facilities and infrastructure. The focus of this research is librarypreneurship and librarypreneur.

Conclusions. The emergence of librarypreneurs is an effect of the creativity and innovation of library science graduates in capturing existing opportunities.
EFFORTS OF HEAD TEACHERS IN LEADING AND MANAGING PUBLIC SCHOOL THROUGH DEVELOPING PROJECTS AND PORGRAMMES
Authors: Subedi, PhD Dhanapati , Pant Chet Nath
Published: November 2023

The paper explores how school leaders of community schools lead and manage schools through the development of innovative projects and programmes creating an engaged learning environment at school. A visionary school leader has a dream of creating an engaged learning environment at school, for which an unwavering determination seems to be a must. The head teachers of the study are found totally focused on their task with full commitment and dedication. They are launching different innovative programs and projects at schools adhering to the notion of innovative school leadership, thereby drawing the attention of the local stakeholders. Like the intent of the theory of flow, these school leaders as campaigners of transformation are immersed in the affairs of school delegating responsibilities to team members. The paper further argues for the need of leading schools proactively and creatively so to create a vibrant learning space where students get opportunities to demonstrate their creativity.
EnviroSense Smart Waste System: Revolutionizing Waste Management Through IoT
Authors: Shenode Nakul Rajesh
Published: November 2023

Abstract: The EnviroSense Smart Waste System is a slice-edge system that uses the power of the Internet of Things (IoT) to transfigure traditional trash operation processes. As urbanization accelerates and environmental enterprises grow a smart and effective waste operation system becomes increasingly important. The EnviroSense Smart Waste System tackles these issues by combining ultramodern detectors, networking, and data analytics to make a complete and long-term waste operation system. The system's introductory operation entails the installation of smart detectors into waste lockers and holders, allowing for real-time monitoring of scrap situations and composition. These detectors use IoT connection to shoot data to a centralized platform, where it's reused by advanced analytics algorithms. The technology gives practicable data, allowing original governments, waste operation enterprises, and other associations to make better opinions.
Automatic Street Light Control and Management System Using Solar Energy
Authors: Nalawade Prof. Mukund
Published: November 2023

Abstract: Electricity waste is a major issue in today's world. The excessive use of electricity by the street lights is one of the main factors in this situation. This undertaking depends on brilliant checking of the streetlamp which will help in lessening the energy utilization issue. In this section, we will make use of a microcontroller, LDR sensor, and IR sensor and solar powered battery pack to automatically turn on and off the street lights whenever they are needed to save power and extend their lifespan. It is suggested that this arrangement could save up to 50% of the energy that is currently used. In comparison to the conventional street lights, this appears to be more cost-effective, sustainable, and efficient
Monitoring of Road Irregularities Using Data Analytics
Authors: Barhate Madhuri Manohar
Published: November 2023

Abstract: This work presents a smartphone-based system that uses orientation and acceleration data to monitor and classify road anomalies in real time. Three severity levels—mild, moderate, and severe—are assigned to irregularities by the system, which also handles their identification, classification, and geotagging. Robust approaches are employed to acknowledge and mitigate challenges such as threshold determination, vehicle-specific vibrations, and smartphone orientation normalization. To ensure a thorough dataset, data collecting entails systematic trials for different types of irregularities. Kalman filtering for noise reduction and a consistent 200 Hz sample rate are used in further preprocessing. A variety of indicators from the Y-axis data are included in feature extraction, which produces a complex dataset for model training. The decision tree approach is used to identify road segments based on extracted data because of its interpretability and transparency
Edukasi Hukum tentang Pelecehan Seksual pada Anak di Sekolah Dasar Negeri, Kota Ambon
Authors: Sihite Sri Rumada
Published: November 2023

Pihak sekolah secara aktif berpartisipasi dalam pembinaan dan pemantauan semua kegiatan siswa untuk menghindari penindasan, terutama terhadap tenaga pendidik. Semua aktivitas siswa juga dapat ditinjau dalam proses pembinaan, dan orang tua diharapkan dapat memberikan bimbingan untuk mencegah bullying yang pada akhirnya merugikan mereka sendiri. Kegiatan pengabdian masyarakat idealnya ini adalah memberikan materi tentang sosialisasi seks dan perundungan (bullying). Tujuan dari kegiatan sosoaliasi ini adalah untuk membantu anak-anak di Sekolah Dasar Negeri Halong di kota Ambon sesuai dengan  karakter generasi yang berakhlak mulia. Selain itu kegiatan ini memiliki tujuan sebagai sinergi antara mitra guru dan sekolah dalam pengembangan pembelajaran, dan mendorong kreativitas dan inovasi di Hinaa.  Sehingga tercapainya peningkatan literasi dan numerasi dan Pelecehan Seksual  di tingkat sekolah dasar sedini mungkin.
 
Abstract
Legal Education regarding Sexual Abuse of Children in State Elementary Schools, Ambon City.
The school actively participates in coaching and monitoring all student activities to avoid bullying, especially towards teaching staff. All student activities can also be reviewed in the coaching process, and parents are expected to provide guidance to prevent bullying which ultimately harms them. The ideal community service activity is to provide material about socialization about sex and bullying. The aim of this socialization activity is to help children at the Halong State Elementary School in Ambon City conform to the character of a generation with noble morals. Apart from that, this activity aims to provide synergy between teacher and school partners in developing learning, and encouraging creativity and innovation at Hinaa. So as to achieve increased literacy and numeracy and bullying at the elementary school level as early as possible.
Urban-rural polarization: Financial implications, challenges, and opportunities
Authors: Mori Margherita
Published: November 2023

This study endeavors to establish a conceptual framework for examining the cross-cultural issues arising from the enduring financial factors contributing to the urban-rural divide. Central to this framework is the notable disparity in available financial services between urban and rural areas. This discrepancy draws attention to the ongoing necessity to combat financial exclusion within agricultural communities. Broadly speaking, it underscores the significance of rural finance, a subset within the financial realm, as a potential means to mitigate the observed polarization. Key factors to be underscored include ongoing technological advancements driving progress in the financial sector and instilling hope in digitization as a catalyst for fostering inclusive finance.
Internet of Things for Project-Based Learning in “Vocational High School Building Village Program”
Authors: Bunyamin Bunyamin
Published: November 2023

This study aims to map the setup of an Internet of things-based project-based learning model as a learning medium in the VHS program to develop communities at SMK Negeri 2 Kuningan in West Java. The research technique is a qualitative and quantitative approach engaging class X-XII students in the field of software engineering competence at SMK Negeri 2 Kuningan via exploratory and in-depth observations. Gunungmanik Village, Kuningan, West Java Province was the location of the internet of things-based learning initiative being implemented. The analysis strategy employs Aiken's formula, and the success factor is confirmed by a panel of experts using an analysis interactive model approach that includes data collecting, data reduction, data presentation, and conclusion drawing. According to the finding of the study the internet of things, project-based learning model in the Village Development Vocational School program was classified into three model configurations, namely: 1) Project based learning based on the internet of things as a medium for developing students' vocational skills in completing student work projects by 69%; 2) Project based learning based on the internet of things serves as a learning medium to place theoretical and practical knowledge in the classroom by 73%; 3)  Project based learning based on the internet of things as a medium for integrating theoretical-practical learning, collaborative learning solutions to contextual problems providing more autonomy to students in the decision-making process by 74%. The result of this PBL was successful to meet the desired outcomes.
Development of pop-up book media based on project-based learning in mathematics learning about flat shapes in elementary schools
Authors: Aini Ika Feny Nur , Nuraini Ni Luh Sakinah , Yuniawatika Yuniawatika
Published: November 2023

Flat building materials have very diverse materials and are considered the most difficult for students to understand. One of the failure factors that occur in students learning is the role of teachers and learning media that is less than optimal. The conditions that occur at SDN Mergosono 1 Malang City which experiences limited learning media to support mathematics learning so students have difficulty in understanding flat building material. Therefore, efforts are needed to optimize the use of media and learning models. This research aims to develop project-based learning-based pop-up book media on grade II elementary school flat building material with valid, practical, and interesting. This development research method uses the ADDIE model (Analyze, Design, Development, Implementation, Evaluation). The validation results of material experts obtained a percentage of 96.28%, media experts 98.86%, and teachers on average 98.33% by getting a very valid category. Student responses in small-scale and large-scale trials obtained an average percentage of 96.28% with very interesting and very practical criteria. So, it can be concluded that project-based learning-based pop-up book media in 2nd grade of elementary school flat building material is very feasible to use.
Comparative Study of Knowledge Level with HIV/AIDS Transmission Prevention Behavior in Junior High School Adolescents in 2022
Authors: Chairani Reni , Izzah Alifia Nurul
Published: November 2023

The problem of HIV/AIDS is still a global health problem, including in Indonesia, which is a country with a high prevalence of HIV/AIDS. Adolescents are one of the groups at risk of contracting HIV/AIDS. The provinces of West Java and DKI Jakarta were provinces that contributed the most cases of HIV/AIDS in recent years. It is necessary to study the level of knowledge and behavior of junior high school youth groups in Depok and Jakarta regarding the prevention of HIV/AIDS transmission. The comparative study method with a cross sectional approach is the research design carried out in this study. by comparing two different groups. The characteristics of the 2 different groups of respondents in this study consisting of age, gender and parental education are the same. The level of knowledge of the respondents in this study had a low level of knowledge equality. The low level of knowledge among junior high school adolescents in Jakarta dominates (64%) compared to junior high school adolescents in Depok (50%) as evidenced by high risk behavior more in junior high school adolescents in Jakarta. The results of the Chi-Square test show that there is a relationship between the level of knowledge and the behavior of preventing HIV/AIDS transmission, because the p value = 0.000 (p value 0.05. In order to increase knowledge about adolescent health, especially HIV/AIDS, which is one of the phenomena prioritized diseases in the world and in Indonesia Health education needs to be included in the education curriculum in schools so that adolescents have good health information and are expected to influence good behavior for adolescents in the future.
How is the Learning Achievement of Elementary School Students?-Breakfast and Study Concentration
Authors: Rachmat Mochamad , Nur Fajri Ashri
Published: November 2023

Background: Learning Achievement is a benchmark of someone in achieving success in the academic field, one of the factors that influence it is the concentration of study and breakfast habits. Breakfast is useful to support learning concentration so that it can improve learning achievement. Learning Consentration affects learning achievement, one way to increase learning concentration is by having breakfast. Purpose: This study aims to analyze The Relationship of Breakfast and Study Concentration with Learning Achievement of Grade 5 Students at SD Negeri Pengasinan 03. Method: Analytical research with cross sectional design, the number samples was 57 students and taken by purposive sampling which fulfilled the inclusion and exclusion criteria. Method: Learning Achievement data obtained from the learning outcomes of even semester students. Breakfast data obtained using the food record method for 2 consecutive days, namely on weekends and weekdays. Study Concentration data obtained by the Digit Symbol Test method and using a stopwatch. Results: Data analysis with Chi-Square test. From 57 students, most of them have a breakfast frequency that is not routine (56,1%). High Study Concentration (64,9%) and Good Learning Achievement (80,7%). There is a significant relationship between breakfast and learning concentration (p-value = 0.008), there is no significant relationship between breakfast and learning achievement (p-value = 0.217), there is a significant relationship between learning concentration and learning achievement (p-value = 0.000).
Indigenous Knowledge of Medicinal Plants in Tribal Community of Antri and Mewara Forest Range of Dungarpur District, Rajasthan
Authors: Patidar Savitri
Published: November 2023

Indigenous knowledge is a valuable knowledge that has been facilitated local ethno- groups of people for survival in all over the world. This knowledge is unique tactic knowledge that originates from the interaction between members of the community and the environment in which they live. It passes through elder generations to younger generations orally or verbally. Knowledge about ethno-medicinal plants and practices make it a survival strategy of livelihood in tribal community of Dungarpur district. However, Dungarpur district is enriched with Deciduous forest covered thus abundant of medicinal plants are identified by these group of people for healthcare purposes. This study is an attempt to identify the ethno-medicinal plants and documentations it with special case studies of the persons who authentically treat and cure community. The field survey was carried out during January 2022 to March 2022 and in July 2022 for identification of plants and know about their story. Outcomes from the field survey revealed that abundant of ethno-medicinal species are found in this area due to its Geographical and Climatic conditions. Since, lack of awareness, lesser interest of Government and local politicians and integument of modernity over younger generation this knowledge has been extinct gradually from the society. There should me need to conserve and protect their traditional legacy of survival with nature.
Evaluate the clinical efficacy of Amrutadi tablet(Anubhut) as palliative care management in oral squamous cell carcinoma w.s.r to tobacco induced oral cancer -a single case study
Authors: Parmar Damini Ben , Kumar Sharma Rajesh , V Sangani Vipulkumar , Padadhariya Dhruval , Ninama Divya Bahen
Published: November 2023

Aim: To Evaluate the clinical efficacy of Amrutadi tablet (Anubhuta)as palliative care management in oral squamous cell carcinoma.

Background: The disease arbuda was prevalent during the Vedic period. In athar-vaveda2 there is reference of arbuda and its management. Arbuda is one of the surgical diseases and was explained in detailed by sushruta the pioneer of in ancient ayurvedic texts that have remarkable similarities with modern interpretation of cancer. Cancer is one of the most dreaded diseases of the 20th century and spreading further with continuance and increasing incidence in 21st century. Cancer is a disease caused by uncontrolled division of abnormal cells in any part of the body.More than 90% of cancer of the tobacco induced oral cancer are squamous cell carcinoma.

Results and Discussion: A case of pain in oral cavity and mouth ulceration after biopsy and mri diagnosed as oral squamous cell carcinoma was given Amrutadi tablet for a period of 30 days. Symptom of pain in oral cavity mouth ulceration and associated symtoms dysphagia, anorexia has been improved moderately within a month. Assesement of patient has been done based on subjective and objective criteria before and after treatment, which shows improvement in patient condition.
The World of Vaccines: Phases of Clinical Trials and Current Status of COVID-19 Vaccines
Authors: Pabbathi Navya , Pasupulati Haritha , Gaddam Soni , SV Padi Satyanarayana
Published: November 2023

The world of vaccines has transformed vaccination by saving millions of lives which otherwise would have killed many people and a hurdle for sustainable development world-wide. Indeed, the coronavirus disease 2019 (COVID-19) pandemic is a public health emergency and an important milestone that revealed how vaccines are really turning point for live changing across the world. Owing to extensive human efforts, vaccines for COVID-19 are discovered and developed and approved globally in less than a year, which is the first time in the history of the world of vaccines. Furthermore, one of the strategic goals of WHO’s ‘The Immunization Agenda 2030’ (IA2030) is the clinical development and approval of 500 new vaccines by 2030. Discovery of immunogens that elicit immune responses is a key step or process by which vaccine candidates have been optimized for further preclinical and clinical trials. Clinical evaluation is carried out in Phases (1-3) and is a sequential approach of establishing safety and efficacy in humans. Regulatory requirements for vaccine approval and licensure to bulk manufacturing are another hurdle. Further, post-marketing safety studies and post-marketing surveillance (Phase 4) are essential to collect the real-world data on safety and effectiveness of the approved vaccines. This review work provides a brief outline on timeline of development of traditional and COVID-19 vaccines and summarizes all the six stages of the vaccine development. Furthermore, current status of COVID-19 vaccines is discussed in view of future approvals.
On Overview of Fast dissolving tablet
Authors: Achal Chavan , Chaudhary Bharatee , Redasani Vivek Kumar , Bhagat Pooja , Mahadik Rutuja
Published: November 2023

Fast dissolving tablets emerge as one of the popular and widely accepted dosage forms, especially for paediatric patients because of incomplete development of the muscular and nervous system and a case of geriatric patients suffering from Parkinson’s disorder or hand tremors. Few solid dosage forms like capsules and tablets are present days facing the problems like difficulty in swallowing (dysphagia), resulting in many incidences of non-compliance and making the therapy ineffective. Oral dosage form and oral route is the most preferred route of administration for various drugs have limitations like first-pass metabolism, psychiatric patients, bedridden and uncooperative patients. FDTs are disintegrating or dissolve quickly in the saliva without a need of water. Fast dissolving tablets are designed to dissolve in saliva remarkably faster, within a few seconds (less than 60 seconds), and those are real fast-dissolving tablets. The convenience of administration and improved patient compliance are important in the design of oral drug delivery system which remains the preferred route of drug delivery in spite of various disadvantages. There are several technologies that are conventional or patented based on spray drying, cotton candy process, sublimation, melt granulation, direct compression freezes drying/lyophilization, phase transition process, mass extrusion, etc. have been developed for manufacturing of FDTs
A Detailed Review on Diabetic Wound Healing Activity
Authors: Bhopale Raman S. , Jangam Rajesh D. , Dhekale Harshada M. , Aiwale Prachi P. , Chaware Vitthal J. , K. Redasani Vivekkumar
Published: November 2023

Skin damage is known as a wound. Hemostasis, inflammatory, proliferative, and tissue remodelling or resolution are the four perfectly timed and highly planned phases that make up the normal biological process of wound healing in the human body. There are two basic categories of wounds: acute wounds and chronic wounds. Long-term negative effects on one's health are caused by the chronic metabolic condition known as diabetes mellitus, which is becoming more common. 25 percent of those with diabetes mellitus are thought to have poor wound healing due to their diabetes. Oxygenation, infection, hormones related to ageing and sex, stress, diabetes, and obesity, drugs, alcoholism, smoking, and diet are among the factors that affect wound healing. To address their basic medical needs, According to estimates, 80% of people who live in underdeveloped nations need traditional medicines, which are typically made from medicinal plants. Numerous individuals in Africa and other poor nations employ using medicinal herbs to cure diabetic wounds and associated issues due to the abundant supply With therapeutic herbs and enough conventional wisdom regarding wounds healing. Recent developments in functional genomics, nanotechnology, wound healing in diabetics, along with a better knowing the pathophysiology of chronic wounds. In the following review, detailed information about healing of diabetic wounds with mechanism, factors affecting, impairment of wound healing  with its pathophysiology, herbal treatments and current advances when treating diabetic wounds are examined.
Registration of Import License for IVD’S In India.
Authors: Yashashri M Inamdar
Published: November 2023

India is a huge market for medical devices and is constantly increasing last few years. The registration certificate and import license is mandatory for manufacturer of India who wishes to import any medical device in India. Indian Agent authorized by CDSCO is required for registering the medical device in India. Duly filled Form MD-14 is required to be submitted for import license registration and license obtained will be in Form MD-15. The review focuses on the regulations concerned to the registration procedures import for new medical device in India with latest amendments in the regulation concerned.
Marine Drugs: A Review
Authors: Gupta Muskan , Kumari Annu , Rankawat Abhishek , Rankawat Gaurav
Published: November 2023

As all of usrecognizebecause ofbigimprovement of the sectorpopulacenumerouspresentreassets of the drug are diminishing and drug builders and producers are looking at for the brand newsources to increase new capsuleswhich aresecure and valuepowerful and effectively meet the growingcall for of world.Marine pharmacognosy gives the scope for studies on thosecapsules on marine origin. As we know marine monographs are very less compared to herbal monographs. Therefore an attempt has been made to explore knowledge on marine pharmacognosy. This assessmentspecializes in marine sources, type of drug molecule of marine organism, numerous marine tabletswith inside themarketplace and strategies to extract numerous biomolecules from seafood waste.