bluuebunny/crossref_metadata_2025 huggingface dataset:
Predictors of postoperative long-term seizure outcome in pediatric patients with focal cortical dysplasia type II at a German tertiary epilepsy center
Authors: Salemdawod Abdallah , Wach Johannes , Banat Mohammed , Borger Valeri , Hamed Motaz , Haberl Hannes , Sassen Robert , Radbruch Alexander , Becker Albert J. , Vatter Hartmut , Surges Rainer , Sarikaya-Seiwert Sevgi
Published: October 2021

OBJECTIVE

Focal cortical dysplasia (FCD) is a common cause of early-onset intractable epilepsy, and resection is a highly sufficient treatment option. In this study, the authors aimed to provide a retrospective analysis of pre- and postoperative factors and their impact on postoperative long-term seizure outcome.

METHODS

The postoperative seizure outcomes of 50 patients with a mean age of 8 ± 4.49 years and histologically proven FCD type II were retrospectively analyzed. Furthermore, pre- and postoperative predictors of long-term seizure freedom were assessed. The seizure outcome was evaluated based on the International League Against Epilepsy (ILAE) classification.

RESULTS

Complete resection of FCD according to MRI criteria was achieved in 74% (n = 37) of patients. ILAE class 1 at the last follow-up was achieved in 76% (n = 38) of patients. A reduction of antiepileptic drugs (AEDs) to monotherapy or complete withdrawal was achieved in 60% (n = 30) of patients. Twelve patients (24%) had a late seizure recurrence, 50% (n = 6) of which occurred after reduction of AEDs. A lower number of AEDs prior to surgery significantly predicted a favorable seizure outcome (p = 0.013, HR 7.63). Furthermore, younger age at the time of surgery, shorter duration of epilepsy prior to surgery, and complete resection were positive predictors for long-term seizure freedom.

CONCLUSIONS

The duration of epilepsy, completeness of resection, number of AEDs prior to surgery, and younger age at the time of surgery served as predictors of postoperative long-term seizure outcome, and, as such, may improve clinical practice when selecting and counseling appropriate candidates for resective epilepsy surgery. The study results also underscored that epilepsy surgery should be considered early in the disease course of pediatric patients with FCD type II.
Determination of the normal conus medullaris level in term infants: the role of MRI in early infancy
Authors: Sun Mengchun , Tao Benzhang , Gao Gan , Wang Hui , Shang Aijia
Published: October 2021

OBJECTIVE

This study aimed to explore the migration process of the conus medullaris (CM) in early infancy using infant MRI and to evaluate the application of MRI for locating the infant CM level.

METHODS

The authors retrospectively analyzed the CM level on the lumbosacral MR images of 26 term infants aged < 3 months who were classified into three groups according to age. The authors numbered the CM level in each patient and analyzed the range and average of the CM level of the cohort. The authors studied the linear correlation between CM level and postnatal days with linear regression analysis, 1-way ANOVA, and the least significant difference test.

RESULTS

The CM level ranged from the superior border of the L1 vertebra to the top third of the L3 vertebra. About 96.2% of infants had CM higher than the superior border of the L3 vertebra. On average, CM was located between the L1–2 intervertebral disc and the inferior border of the L2 vertebra (mean ± SD score 1.64 ± 1.14). The three groups had no significant statistical difference in CM level (F = 1.071 and p = 0.359; groups 1 and 2, p = 0.408; groups 1 and 3, p = 0.170; groups 2 and 3, p = 0.755). CM level had no linear regression correlation with postnatal days within the first month (r2 = 0.061, F = 0.654, p = 0.438) or within the first 3 months (r2 = 0.002, F = 0.056, p = 0.816).

CONCLUSIONS

The CM level reaches the normal adult level by birth in term infants and does not ascend during childhood. On average, the CM was between the L1–2 intervertebral disc and the inferior border of the L2 vertebra in term infants. Considering the possibility of physiologically low-lying CM, the authors agree that normal CM is located above the L3 level in term infants and CM at the L3 level could be equivocal and should be investigated with other clinical data. The study data suggest that MRI is an accurate and valuable method for determining the CM level in term infants.
What We Should Not Forget about Down Syndrome
Authors: Fragoso D.C. , Nunes D.M. , Maia A.C.M. , Garcia L.A.L. , Alves H.C.B.R. , da Silva C.J. , Leite C.C.
Published: October 2021

Down syndrome is the foremost common genetic cause of intellectual disability. The additional copy of chromosome 21 confers potential changes in virtually all organ systems, including the brain, neck structures, and spine. Neuroradiologists should be aware of the multitude of imaging findings in patients with Down syndrome to correctly identify and diagnose life-altering conditions associated with this syndrome. In particular, the high prevalence of age-related cognitive decline and dementia stands out more clearly in recent decades due to the notable increase in these individuals' survival. Although the early and timely diagnosis of cognitive decline in patients with varying degrees of intellectual disability has not been an easy task from the clinical point of view, anatomic and functional brain studies have shown an essential role because they allow the early recognition of abnormalities that precede the cognitive decline. Furthermore, the similarities and differences in neuropathologic, genetic, and imaging aspects in patients with Down syndrome have allowed extrapolation for a better understanding of the mechanisms linked to Alzheimer disease development.Learning Objective: To review and systematize the distinctive characteristics and abnormalities of the head and neck, vertebral column, and CNS present in Down syndrome
Opercular Perivascular Cyst: Old Entity, New Location
Authors: Page I. , McArdle D.J.T. , Gaillard F.
Published: October 2021

Dilated perivascular spaces in the brain have typical neuroimaging appearances. The classification of dilated perivascular spaces is based on their relationship to blood vessels and is divided into 3 subtypes. A fourth type has been described and termed “opercular perivascular space.” We report on an incidental finding of an opercular perivascular space on MR imaging. Dilated perivascular spaces are benign; it is important to be familiar with their characteristic appearance to prevent reporting them as a neoplasm.
Encephalotrigeminal Angiomatosis: A Review with Emphasis on Head and Neck Manifestations
Authors: Larsen B.R. , Rosztoczy M.S. , Van Tassel D.C. , Larson C.R. , Avedikian S.A. , Gridley D.G.
Published: October 2021

Encephalotrigeminal angiomatosis, also known as Sturge-Weber syndrome or Sturge-Weber-Dimitri disease, is a sporadic congenital neurocutaneous syndrome characterized by angiomas of the face, eyes, and meninges. The typical clinical findings include seizures, a port-wine facial nevus,
hemiparesis, and developmental delay. The classic intracranial imaging features of Sturge-Weber syndrome include cerebral hemispheric atrophy, hypervascularity and/or calcification of the cortex, and ipsilateral choroid plexus enlargement. Extracranial findings primarily include the vascular
abnormalities of the ocular and facial soft tissues as well as hypertrophy of the calvarial and maxillofacial osseous structures. Additionally, we report involvement of the extraocular muscles, salivary glands, and lacrimal glands, findings that have not been well described in the literature.
While a developmental venous pathology underlying Sturge-Weber syndrome has been proposed resulting in many of the findings, the mechanism behind the facial soft-tissue abnormalities and the clinical sequelae associated with these glandular abnormalities is still uncertain.Learning Objective:
To recognize typical clinical and various imaging manifestations of Sturge-Weber syndrome, including head and neck and intracranial imaging findings
Heinrich Gross of Würtemberg: A Diplomat on Elizabeth Petrovna's Service
Authors: Anisimov Maksim
Published: October 2021

Heinrich Gross was a diplomat of the Empress of Russia Elizabeth Petrovna, a foreigner on the Russian service who held some of the most important diplomatic posts of her reign. As the head of Russian diplomatic missions in European countries, he was an immediate participant in the rupture of both Franco-Russian and Russo-Prussian diplomatic relations and witnessed the beginning of the Seven Years' War, while in the capital of Saxony, besieged by Prussian troops. After that H. Gross was one of the members of the collective leadership of the Russian Collegium of Foreign Affairs. So far there is only one biographic essay about him written in the 19th century. The aims of this article are threefold. Using both published foreign affairs-related documentation and diplomatic documents stored in the Archive of the Foreign Policy of the Russian Empire, it attempts to systematize the materials of the biography of this important participant in international events. It also seeks to assess his professional qualities and get valuable insight into his role both in the major events of European politics and in the implementation of the foreign policy of the Russian Empire in the mid-18th century. Moreover, the account of the diplomatic career of H. Gross presented in this essay aims to generate genuine interest among researchers in the personality and professional activities of one of the most brilliant Russian diplomats of the Enlightenment Era.
Queer_feministische Soziale Arbeit als Arbeit an der Sichtbarkeitsfalle
Authors: Kasten Anna
Published: October 2021

Die Sozialarbeitenden können dann handeln, wenn soziale Probleme sichtbar sind. Dabei stellt sich die Frage, wie queer_feministische Soziale Arbeit konzeptualisiert werden kann, dass sie die Macht der Heteronormativität entlarvt und neue Imaginationen der Zugehörigkeit möglich/denkbar macht und dass ihre eigenen Verstrickungen in die Normalisierungs- und Ausschlussprozesse zum Vorschein kommen. In meinem Beitrag skizziere ich einen theoretisch begründeten Ansatz queer_feministischer Sozialer Arbeit, die ich als Arbeit an der Sichtbarkeitsfalle konzeptualisiere. Diese Sichtbarkeitsfalle umschreibe ich mit der Interdependenz von drei Momenten: die Provinzialisierung der Heterosexualität als Norm, die Adressierung einer bestimmten sozialen Verletzlichkeit und die Verortung des Problems in den Subjektivierungsweisen. Der Fokus auf die Sichtbarkeit veranschaulicht den Zusammenhang zwischen gesellschaftlicher/rechtlich-politischer Ordnung von Geschlecht und Sexualität, Subjektivierungsweisen der Adressat*innen der Sozialen Arbeit sowie dem professionellen sozialarbeiterischen Handeln.
Vehicle License Plate Detection Using Bounding Box Technique
Authors: Vanitha N  , Rene Robin C R  , Doreen Hephzibah Miriam D  , SankarGanesh N
Published: October 2021

The use of vehicles in our daily lives is growing rapidly, and as more vehicles violate traffic laws, theft of vehicles, and a high number of incidents occur, crime rates rise linearly. Vehicle License Plate Detection (VLPD) is a image processing technology for recognizing the vehicle number plate. In a typical VLPD the image of the vehicle is first detected and the vehicle license plate region is captured. Then the filtering techniques are applied to the captured license plate region. In this study bounding box technique is applied for the segmentation and character recognition. It is observed that the created framework effectively detects and recognizes the vehicle number on different test pictures.
Predictive Analysis of Postpartum Haemorrhage Using Deep Learning Technique
Authors: Ruphitha S.V. , Ambeth Kumar V.D.
Published: October 2021

Postpartum haemorrhage is the prime source of parental fatality. Postpartum haemorrhage occurs extra blood loss after delivery. If the blood loss occurs more than 500ml, it may create a problem in blood pressure where the women has to go through a lot of pain. Presently, the complete cure are still under research and there is no result which helps to dwindle the endanger of postpartum haemorrhage. Intent process is so supportive in classifying the danger circumstances and current automation is used. The methodology used here is Deep Learning technique which will be easier to conclude the postpartum haemorrhage in the previous phase. There is an certain stage of postpartum haemorrhage where it can control the blood loss and save the women by permitting higher level treatments. Haemorrhage is one of the major factor responsible for maternal death. Haemorrhage may occur before, during or after delivery of placenta. Based on the amount of blood flow, postpartum haemorrhage will be classified in to two types such as primary and secondary pph. To manage all these problems, methods are handled based on respective situation.
A Review Based on Secure Banking Application Against Server Attacks
Authors: Revathy P  , Belshia Jebamalar G
Published: October 2021

In recent years, attacks on online based transaction become very common and are widespread, which makes the banking server compromised by using users account and personal information without authorization. To address the security concerns, also gain user trust and confidentiality, we propose automatic detecting and prevent bank attacks such as DDOS and SQL injection. Also, to eliminate bot-based attacks we enhance security at the authentication phase by invoking OTPthereby preventing brute force attack. The proposed system generates unique CAPTCHA for validating the user transaction. Hence it is difficult for intruder to perform unauthorized activities within the banking application. Finally,the proposed system secures user password from traditional approach using negative password generation technique. Thus, we conclude by combining all the three techniques together for the secured banking application.
The Solution for XML External Entity Vulnerability in Web Application Security
Authors: Prabhakar.M  , Syed Abdul Raheem
Published: October 2021

Web application security the basic requirement and follow as a minimum security standard nowadays to develop online applications. Most of the web applications are managing online transaction like transferring money, pay bills online and many more services related to finance. So, all the web transactions are exchanged of static data related to both the bank parties which is used to populate XML document. And the SOAP web services and REST protocol are used for exchange of two heterogeneous applications and the data is parsed by XML parser. XML External Entity attack occurs as XML input weakly parsed data. This attack refers problems like confidential information, denial of service and server side request information. In this paper we explain about XML External Entities, prevention measures, problems and expected solutions.
Topic Detection Using Multiple Semantic Spider Hunting Algorithm
Authors: Elakiya E. , Kanagaraj R. , Rajkumar N.
Published: October 2021

In every moment, there is a huge capacity of data and information communicated through social network. Analyzing huge amounts of text data is very tedious, time consuming, expensive and manual sorting leads to mistakes and inconsistency. Document dispensation phase is still not accomplished of extracting data as a human reader. Furthermore the significance of content in the text may also differ from one reader to another. The proposed Multiple Spider Hunting Algorithm has been used to diminish the time complexity in compare with single spider move with multiple spiders. The construction of spider is dynamic depends on the volume of a corpus. In some case tokens may related to more than one topic and there is a need to detect Topic on semantic way. Multiple Semantic Spider Hunting Algorithm is proposed based on the semantics among terms and association can be drawn between words using semantic lexicons. Topic or lists of opinions are generated from the knowledge graph. News articles are gathered from five dissimilar topics such as sports, business, education, tourism and media. Usefulness of the proposed algorithms have been calculated based on the factors precision, recall, f-measure, accuracy, true positive, false positive and topic detection percentage. Multiple Semantic Spider Hunting Algorithm produced good result. Topic detection percentage of Spider Hunting Algorithm has been compared to other algorithms Naïve bayes, Neural Network, Decision tree and Particle Swarm Optimization. Spider Hunting Algorithm produced more than 90% precise detection of topic and subtopic.
MRI Brain Abnormality Detection Using Conventional Neural Network (CNN)
Authors: Jeevitha R  , Selvaraj D
Published: October 2021

Brain tumours has huge heterogeneity and there is always a familiarity between normal and abnormal tissues and hence the extraction of tumour portions from normal images becomes persistent. In this paper, MRI brain tumor detection is performed from a brain images using Fuzzy C-means(FCM) algorithm and sebsequently Convolutional Neural Network(CNN) algorithm is employed. Here, firstly preprocessing step is performed by Skull Stripping algorithm followed by Segmentation process. Fuzzy C-means algorithm is used to segment the Cerebrospinal Fluid(CSF), Grey matter(GM) and White Matter(WM) from the database. The third part is to extract features to find whether the tumor is present or not, here eleven features are extracted like mean, entropy, S.D(Standard Deviation). The final part is the classification process done by Convolutional Neural Network(CNN) in which it is able to differentiate whether the input image is normal image or an abnormal image. Compared to other methods, here the values of the features extracted are higher for normal images than for abnormal Images and it is shown from the graphs drawn from the extracted features.
Effects of a physical self-care support program for patients with fibromyalgia: A randomized controlled trial
Authors: de Lorena Suélem B. , Duarte Angela L.B.P. , Bredemeier Markus , Fernandes Vanessa M. , Pimentel Eduardo A.S. , Marques Cláudia D.L. , Ranzolin Aline
Published: October 2021

BACKGROUND: The effects of stretching exercises in fibromyalgia (FM) deserves further study. OBJECTIVE: To evaluate the effectiveness of a Physical Self-Care Support Program (PSCSP), with emphasis on stretching exercises, in the treatment of FM. METHODS: Forty-five women with FM were randomized to the PSCSP (n= 23) or to a control group (n= 22). The PSCSP consisted of weekly 90-minute learning sessions over 10 weeks, providing instructions on wellness, postural techniques, and active stretching exercises to be done at home. The control group was monitored through 3 medical appointments over 10 weeks and included in a waiting list. The primary outcomes were the Fibromyalgia Impact Questionnaire (FIQ), the Visual Analogue Scale (VAS) for pain, and the Sit and Reach Test (SRT) at the end of the study. RESULTS: Nineteen and 21 patients completed the trial in PSCSP and control groups, respectively. After 10 weeks, the PSCSP group showed significantly better FIQ (difference between adjusted means, -13.64, 95% CI, -21.78 to -5.49, P= 0.002) and SRT scores (7.24 cm, 3.12 to 11.37, P= 0.001) than the control group, but no significant difference in pain VAS (-1.41, -3.04 to 0.22, P= 0.088). Analysis using multiple imputation (MI) and delta-adjusted MI for missing outcomes rendered similar results. CONCLUSIONS: A PSCSP emphasizing stretching exercises significantly improved FIQ and SRT scores, and may be a helpful therapy for FM.
Aberrant STAT1 methylation as a non-invasive biomarker in blood of HCV induced hepatocellular carcinoma
Authors: Zakir Umaira , Siddiqui Nadir Naveed , Naqvi Faizan-ul-Hassan , Khan Rizma
Published: October 2021

BACKGROUND: Hepatocellular carcinoma (HCC) is one of the most common types of cancer in the world and a reason behind different oncogenes activation and tumor suppressor genes inactivation. Hyper-methylation of tumor suppressor genes including RASSF1a, GSTP1, p16, and APC cause gene silencing as well as tumor cell invasion. STAT 1 gene is a part of signaling cascade of JAK/STAT and any dysregulation in signaling has been implicated in tumor formation. OBJECTIVE: The current investigation focus on the methylation role of STAT1 gene as a non-invasive biomarker in the progression and diagnosis of hepatocellular carcinoma. METHODS: STAT1 gene methylation status in 46 HCV induced hepatocellular carcinoma patients and 40 non-HCC controls were examined by methylation specific PCR. STAT1 gene expression was examined by real time PCR and further validated by various bioinformatics tools. RESULTS: STAT1 methylation in HCV-induced HCC (67.4%) was significantly higher compared to the non-HCC controls (p< 0.01). However, mRNA expression of STAT1 gene in methylated groups was significantly lower compared to unmethylated groups (p< 0.05). Furthermore, insilco analysis of STAT1 validated our results and shown expression of STAT1 mRNA was lower in liver cancer with the median 24.3 (p= 0.085). CONCLUSION: After using peripheral blood samples we observed that STAT1 silencing caused by aberrant methylation could be used as potential non-invasive biomarker for the diagnosis of HCV induced hepatocellular carcinoma. We conclude that blood as a sample source could be used instead of biopsy for early detection of HCC.
Dysregulation of ECRG4 is associated with malignant properties and of prognostic importance in human gastric cancer
Authors: You Yanjie , Hu Shengjuan
Published: October 2021

BACKGROUND: We have previously characterized esophageal carcinoma-related gene 4 (ECRG4) as a novel tumor suppressor gene, which is frequently inactivated in nasopharyngeal carcinoma and breast cancer. Nevertheless, the expression status and prognostic significance of ECRG4 maintain elusive in human gastric cancer. Herein, we examined ECRG4 expression profile in gastric cancer and assessed its association with clinicopathological characteristics and patient survival. METHODS: Online data mining, real-time RT-PCR and immunohistochemistry were employed to determined ECRG4 expression at transcriptional and protein levels in tumors vs. noncancerous tissues. Statistical analyses including the Kaplan-Meier survival analysis and the Cox hazard model were utilized to detect the impact on clinical outcome. Moreover, ECRG4 expression was silenced in gastric cancer SGC7901 cells, and cell proliferation, colony formation and invasion assays were carried out. RESULTS: ECRG4 mRNA and protein levels were obviously downregulated in cancer tissues than noncancerous tissues. Statistical analyses demonstrated that low ECRG4 expression was found in 34.5% (58/168) of primary gastric cancer tissues, which was associated with higher histological grade (P= 0.018), lymph node metastasis (P= 0.011), invasive depth (P= 0.020), advanced tumor stage (P= 0.002) and poor overall survival (P< 0.001). Multivariate analysis showed ECRG4 expression is an independent prognostic predictor (P< 0.001). Silencing ECRG4 expression promoted gastric cancer cell growth and invasion. Western blot analysis revealed the anti-metastatic functions of ECRG4 by downregulating of E-cadherin and α-Catenin, as well as upregulating N-cadherin and Vimentin. CONCLUSIONS: Our observations reveal that ECRG4 expression is involved in gastric cancer pathogenesis and progression, and may serve as a candidate prognostic biomarker for this disease.
Impact of training perception on affective commitment and the mediating role of work engagement: Evidence from the hospitality sector of Pakistan
Authors: Solangi Rukhman , Afshan Gul , Siyal Saeed , Shah Samar Batool
Published: October 2021

BACKGROUND:

Given the importance and issues about the hospitality industry, commitment has remained a significant concern for human resource managers and researchers. This paper aims to develop the insights by assessing perceptions of training and work engagement as predictors of commitment among hospitality employees in Pakistan.

OBJECTIVE:

Following social exchange theory, this study investigated the relationship between five training perceptions: perceived access to training (PAT), motivation to learn (MLT), perceived benefits (PBT), perceived supervisory support (PSST), and coworker support (PCST) and the affective commitment via work engagement.

METHOD:

Employing survey-based data, this study analyzed 239 responses from the front-line employees in Pakistan’s hospitality industry.

RESULTS:

Smart-PLS results reveal that only PAT and PCST significantly predicted affective commitment out of five training perceptions. Similarly, work engagement was found to mediate the relationship between training perception and affective commitment except for MLT. The study also found that work engagement had the most substantial mediating effect between PSST and affective commitment.

CONCLUSION:

Organizations invest a lot of money in training and developing their employees to derive desired organizational outcomes. Therefore, it is important to consider perceptions of training while designing and delivering training. For organizational commitment, it is important that employees feel motivated to contribute to the organization and reciprocate with engagement and commitment with the organization.
The mechanism underlying the relationship between empowering leadership and work passion
Authors: Elsaied Mervat Mohammed
Published: October 2021

OBJECTIVE:

The purpose of this paper is to investigate the effect of empowering leadership (EL) on work passion by developing a moderated mediation model. The model focuses on the mediating effect of intrinsic motivation (IM) in the relationship between EL and work passion, as well as the moderating effect of role clarity (RC) in influencing the mediation.

METHODS:

Data were obtained from a sample of 515 workers, who work in 17 five-star hotels in Sharm El-Sheikh.

RESULTS:

Findings reveal that IM fully mediates the positive relationship between EL and work passion. It also concluded that RC moderated the mediated relationship between EL and work passion via IM, with individuals with higher RC benefiting more from the mediation.

CONCLUSION:

The findings have far-reaching implications for both employees and leaders. Furthermore, they add to our understanding of self-determination theory and cognitive evaluation theory in terms of consolidating employees’ work passion.
Media use, information reliability and political efficacy in Tunisia, 2011–2019
Authors: Kavanaugh Andrea , Sheetz Steven , Skandrani Hamida , Sghaier Malek
Published: October 2021

Information access and open communication – through in person and mediated information and communication technology – are critical to an informed citizenry in democratic societies. The 2011 Arab Spring uprising that originated in Tunisia and resulted in the overthrow of long-time Tunisian authoritarian president Ben Ali, established a new transitional government with more democratic institutions and more open press and political expression. In this paper, we explore changes over time (2011–2019) in the use by young, educated Tunisians of different political information sources, the perceived reliability of these sources, their information sharing behavior, and sense of being politically well-informed (i.e., political information efficacy). We report here results from the third of three surveys we administered of an online questionnaire to three different but comparable opportunity samples of young, educated Tunisians. The first two surveys conducted in 2012 and 2015 have been previously reported. We compare results from the most recent survey regarding 2019 elections with findings from the two prior surveys. Our findings confirm increasing perceived reliability of government information sources during the 2014 and 2019 elections, and decreasing reliability of social media. Results also confirm that higher perceptions of information reliability along with information sharing, lead to greater political information efficacy which is an important predictor of further democratic political participation.
The association between recently diagnosed cancer and incidence of falling in older adults: An exploratory study
Authors: Tough Daniel , Batterham Alan , Loughran Kirsti , Robinson Jonathan , Dixon John , Ryan Cormac G. , Wellburn Shaun , Harrison Samantha L.
Published: October 2021

INTRODUCTION: More than one in three older adults (≥65 years) fall within a two-year period. Over one third of cancer diagnoses are among people aged ≥75 years. Falls research in the UK cancer population is limited and contradictory. The aim of this study was to explore the association between a cancer diagnosis and incidence of falls in older adults in England. METHODS: Data were extracted from the English Longitudinal Study of Ageing (an ongoing panel study) collected between 2002 and 2014, consisting of a representative cohort of older adults living in England. Baseline data were collected within two-years of a cancer diagnosis. Falls data were extracted from the subsequent two-year period. The unexposed group included those with no chronic conditions. The fully adjusted logistic regression analysis model included age, sex, wealth, and education level as covariates. We defined odds ratios between 0.67 and 1.5 as the region of practical equivalence. RESULTS: A total of 139 people had a type of cancer (exposed group) (Breast = 18.7%, Colon, Rectum or Bowel = 14.4%, Melanoma or Skin = 7.2%, Lung = 4.3%, Somewhere else = 51.8%) (70.6±7.1 years; 58.3% male) with 3,899 in the unexposed group (69.5±7.3 years; 54.6% male). The fully-adjusted odds ratio was 1.21 (95% CI: 0.81 to 1.82; P = 0.348). The probability of falling among the exposed group was 22.7% versus 19.5% for the unexposed group. CONCLUSION: The cancer and control groups were not statistically equivalent for falls incidence, and a meaningful positive association between cancer and falls cannot be ruled out. Further research is required to elucidate this relationship.
Increase of activation efficiency of hardening backfilling mixture components by application mining and metallurgical wastes
Authors: Dmitrak Yu. V. , Golik V. I. , Franchuk V. P. , Lyashenko V. I.
Published: October 2021

The main operation associated with the preparation of mining and metallurgical wastes for use as a hardening mixture and backfilling of mined-out space is their crushing and activation. Improving the activation processes is an urgent task, since their use can significantly increase the strength of the filling mass or reduce the consumption of the binder while maintaining its strength characteristics. For the efficient operation of mining enterprises, including ferrous metallurgy mines, it is necessary to provide highquality binders for the preparation of hardening mixtures for filling man-made voids formed during underground mining of solid mineral deposits. It has been established that the use of vibration, mechanical and electrical activation of the components of the hardening backfill mixture at mining enterprises leads to an increase in the activity of substandard materials by up to 10–40% for each apparatus. In particular, the enrichment of inert materials on a vibrating screen ГВ-1,2/3,2, Ukraine, increases the activity by 15– 20%. It has been substantiated that the activation of binders (blast-furnace granular slags) in a vertical vibrating mill МВВ-0,7, Ukraine, and a disintegrator ДУ-65 company “Disintegrator”, Estonia, increases the activity of the binder by 20–25%, when the active class of fractions 0.074 mm – by 55% is released versus 40% in ball mills. The recommended vibratory conveying installations increase the activity of the components of the hardening backfill mixture by 10–15%. The use of vibro-gravity transport installations ensures the supply of the filling mixture at a distance 15–20 times higher than the height of the vertical stack.
Modern state and directions of perfection of technological processes of manufacturing hardened-tempered spring wire
Authors: Kharitonov V. A. , Smetneva N. Yu.
Published: October 2021

Hardened-tempered spring wire has a great demand in domestic automobile industry. A considerable part of such a wire is imported. In view of increase of demand in treated wire for springs of critical application and measures implementation for import substitution, perfection of technological processes of its production becomes actual. Basic technical requirements to spring wire as per domestic and foreign standards presented, the factors effecting the quality of finished products considered. Description of technological processes of hardened-tempered spring wire of critical application presented. It was shown that domestic technological scheme of treated wire production is analogous to foreign one, however to reach the quality of products, correspondent to norms нормам EN 10270-2:2012, a perfection of it is needed. Proposals to improve the technology of manufacturing domestic competitive products elaborated. Among them a necessity to use steels of Si‒Cr or Si‒Cr‒V system, additionally alloyed by manganese, cobalt, tungsten a(or) other elements highlighted. It was proposed to implement an operation of scalping instead of turning and a system of nondestructive control, to use resource-saving routes of wire drawing with high uniformity of properties, to replace hardening and tempering by thermomechanical treatment (for some kinds of wire), to use modern highly-productive equipment.
Assessing the state of a complex ergatic system on the example of a system for ensuring the uniformity of measurements
Authors: Krasavin Ilya V. , Yashin Andrey V.
Published: October 2021

Assessment of the state of the system of ensuring the uniformity of measurements is an urgent task, the solution of which is necessary for monitoring and forecasting its state. The paper proposes an approach to the development of a methodology for monitoring the state of the system to ensure the uniformity of measurements and forecasting its state, which takes into account the mutual influence of subsystems on each other. The approach is based on the hierarchy analysis method. The decomposition of the system of ensuring the uniformity of measurements for further processing of the sequence of judgments of the person (group of persons) making the decision is considered. The judgments are based on paired comparisons of the decomposition elements. The method of processing the judgments of a group of experts in order to obtain a generalized judgment on paired comparisons is described. The obtained results can be used as part of monitoring the state of the system for ensuring the uniformity of measurements and forecasting the measurement needs of the economy and society.
Model for estimating the heterogeneity of the distribution of globule characteristics in images of skin neoplasms
Authors: Nikitaev Valentin G. , Pronichev Alexandr N. , Tamrazova Olga B. , Sergeev Vasily Yu. , Selchuk Vladimir Yu. , Kozlov Vladimir S. , Lim Alina O.
Published: October 2021

The problem of skin melanoma diagnostics from digital images of the tumor is considered. Clinical algorithms for detecting skin melanoma are briefly described. An overview of the works devoted to the automated assessment of the asymmetry of the distribution of shape, color, area of globules – important signs of melanoma – is given. A model for estimating the heterogeneity of the distribution of the characteristics of globules on digital images in the skin neoplasms diagnosis is developed and models of signs of heterogeneity of this distribution are proposed. The comparative evaluation of the proposed models was carried out experimentally using a software system developed in C++. The most informative features are identified. The greatest accuracy 93 % in estimating the heterogeneity of the distribution of the characteristics of globules was shown by the sign “the reduced inverse of the greatest frequency of occurrence of the measured areas of globules”. The results obtained can be applied in the development of systems to support medical decision-making in the diagnosis of melanoma.
National standards of the harmonic coefficient unit of the Russian Federation and the Republic of Belarus: results of comparisons
Authors: Bedenezhnykh Sergey V. , Kaminsky Oleg V. , Stal’nova Kseniia A. , Galygo Alexander V. , Gerasimova Nadezhda A.
Published: October 2021

The results of additional comparisons of the national standards of the unit of the harmonic coefficient of Russia (VNIIFTRI) and the Republic of Belarus (BelGIM) are presented. A mass-produced harmonic coefficient meter was used as a reference carrier. The differences between the harmonic coefficient unit reproduced by national standards the reference values do not exceed the extended uncertainty for all measured values of the harmonic coefficient and at all frequencies. Thus, the measurement and calibration capabilities of the laboratories participating in the comparisons are confirmed.
Efektivitas Pembelajaran Daring di Indonesia
Authors: Syahri Syahri
Published: October 2021

The outbreak of the coronavirus in Indonesia affects all aspects of life including aspects of education.Learning that all goes face-to-face is now converted into online learning. This online learning is carriedout using internet media and various platforms which are now widely spread in Indonesia. Onlinelearning is one alternative that can overcome the challenge. This study aims to determine theeffectiveness of online learning that emphasizes integration with the environment from various sourcesin terms of various aspects during the educational era 4.0. Using the method in the form of a metaanalysis of journals, through a variety of journals related to the research variables collected thenreviewed and drawn a conclusion. The results of the study show that online learning will be effective ifit applies an essential component of Laurillard which covers aspects of discourse, adaption, interactionand reflection.
The Efficacy of Genistein-Rich Edamame as a Prevention of Atherosclerotic Lesion in Abdominal Aorta: Study in Rats Model of Atherosclerosis
Authors: Fardhani Rizky Aditya , Reza Dian Pratama  , Nani Maharani  , Bahrudin  , Yuriz Bakhtiar  , M Ali Sobirin  , Farmaditya EP Mundhofir
Published: October 2021

Background: Atherosclerosis is the main cause of ischemic heart disease which leads to death for people aged more than 40 years old. Genistein is an important isoflavone compound which may protect the blood vessels from endothelial injury. This research is to observe the efficacy of genistein rich edamame as a prevention for atherosclerotic abdominal aortic lesions that seen from abdominal aortic thickness and foam cells count.

Method: Thirty rats were divided randomly into five groups and treated for 28 days. The negative control group was given food and drink ad libitum. The positive control group was induced for atherosclerosis using adrenaline 0.006 mg / 200 gr BW injected on the first day and then the next day was given egg yolk 5 gr / 200 gr BW on next day for 28 days. All of the treatment groups were induced for atherosclerosis and treated with genistein-rich edamame extract 5 mg / 200 gr BW, edamame extract 38 mg / 200 gr BW and atorvastatin 1.5 mg / 200 grBW. Data were analyzed using One Way ANOVA - post hoc Bonferroni test, Kruskal Wallis - Mann Whitney test, and Pearson correlation test.

Results: There were significant differences (p<0,001) in abdominal aortic thickness and foam cells count between positive control group and treatment genistein-rich edamame extract, edamame extract and atorvastatin. There was a significant correlation between the abdominal aortic wall thickness and foam cells count (correlation coefficient value 0,753; p<0,001).

Conclusion: The administration of genistein-rich edamame extract can prevent the thickening of abdominal aorta and foam cell formation. Genistein-rich edamame can prevent foam cells formation better than atorvastatin.
Analysis on the Basic Narrative Structure of Short Films
Authors: Liu Anran
Published: October 2021

This paper makes a basic analysis on the narrative structure of short films. The first is to analyze how roles setting promoted the development of the story; the second is to analyze mainly three acts on narrative short films; the third is to analyze narrative structure on Melodrama which is a kind of genre convention adopted by most popular movies. Through the above three aspects, the basic narrative structure of short films upheaval is revealed.
Pengaruh Gaya Kepemimpinan Transformasional dan Budaya Organisasi Terhadap Organizational Citizenship Behavior Melalui Komitmen Organisasi
Authors: Anam Rohmat Khoirul , Rizana Dani
Published: October 2021

This study aims to examine the effect of transformational leadership style and organizational culture on organizational citizenship behavior through organizational commitment as an intervening variable. The sampling method used was simple random sampling, that is, the sample was taken randomly without paying attention to the strata in the population. Respondents in this study were 63 employees of UPTD Waste Water and Garbage Management in the Eastern Region of the Perkim LH Office of Kebumen Regency. This research used descriptive analysis method and statistical analysis which carried out validity test, reliability test, multicollinearity test, heteroscedasticity test, normality test, correlation test, determination coefficient test, t test, path analysis, and single test. Testing in the t test shows that transformational leadership style has a positive and significant effect on organizational commitment to employees of UPTD Pengelolaan air Limbah dan Sampah Wilayah Timur Dinas Perkim LH Kabupaten Kebumen, organizational culture has a positive and significant effect on organizational commitment, transformational leadership style has no effect on organizational citizenship. behavior, organizational culture has a positive and significant effect on organizational citizenship behavior, organizational commitment has a positive and significant effect on organizational citizenship behavior, organizational commitment can mediate transformational leadership styles and organizational citizenship behavior, and organizational commitment can mediate organizational culture and organizational citizenship behavior.
Pengaruh Autenthic Leadership, Person Job Fit, dan Quality of Work Life Terhadap Komitmen Afektif Guru
Authors: Ngaenurrohmah Ngaenurrohmah , Prasetyo Anton
Published: October 2021

Penelitian ini dilakukan untuk mengetahui pengaruh autethic leadership, person job fit, dan quality of work life terhadap komitmen afektif guru SMK Negeri 1 Ambal. Data yang digunakan dalam penelitian ini adalah data primer. Penelitian ini menggunakan 37 responden sebagai sampel penelitian yang ditarik berdasarkan sampling jenuh. Pengambilan data menggunakan kuesioner berdasrkan skala likert yang telah dimodifikasi dengan 4 skala. Metode analisis data menggunakan analisis regresi linear berganda dengan bantuan SPSS 23 for windows. Hasil penelitian berdasarkan uji t menunjukkan bahwa variabel autenthic leadership tidak berpengaruh signifikan terhadap komitmen afektif guru SMK Negeri 1 Ambal. Variabel Person job fit tidak berpengaruh terhadap komitmen afektif guru SMK Negeri 1 Ambal. Variabel quality of work life berpengaruh signifikan terhadap komitmen afektif guru SMK Negeri 1 Ambal.Variabel autenthic leadership, person job fit, dan quality of work life secara bersama-sama berpengaruh signifikan terhadap komitmen afektif guru SMK Negeri 1 Ambal.
Pengaruh Gaya Kepemimpinan Transformasional, Person Organization Fit, dan Motivasi Kerja terhadap Komitmen Guru
Authors: Hidayah Sri Rodhotul , Prasetyo Anton
Published: October 2021

Penelitian ini dilakukan untuk mengetahui pengaruh gaya kepemimpinan transformasional, person organization fit, dan motivasi kerja terhadap komitmen guru SMK Ma’arif 9 Kebumen. Data yang digunakan dalam penelitian ini adalah data primer. Penelitian ini menggunakan 39 responden sebagai sampel penelitian yang ditarik berdasarkan sampling jenuh. Pengambilan data menggunakan kuesioner berdasrkan skala likert yang telah dimodifikasi dengan 4 skala. Metode analisis data menggunakan analisis regresi linear berganda dengan bantuan SPSS 23 for windows. Hasil penelitian berdasarkan uji t menunjukkan bahwa variabel gaya kepemimpinan transformasional berpengaruh signifikan terhadap komitmen guru SMK Ma’arif 9 Kebumen. Variabel Person organization fit tidak berpengaruh terhadap komitmen guru SMK Ma’arif 9 Kebumen. Variabel motivasi kerja tidak berpengaruh signifikan terhadap komitmen guru SMK Ma’arif 9 Kebumen.Variabel gaya kepemimpinan transformasional, person organization fit, dan motivasi kerja secara bersama-sama berpengaruh signifikan terhadap komitmen guru SMK Ma’arif 9 Kebuemn. Hasil pengujian koefisien determinasi nilai R Square variabel komitmen guru dipengaruhi oleh  variabel gaya kepemimpinan transformasional, person organization fit, dan motivasi kerja sebesar 39,4 % dan sisanya 60,6 % variabel komitmen guru dipengaruhi oleh variabel-variabel diluar model penelitian ini.
Pengaruh Kepemimpinan, Beban Kerja dan Kompensasi Terhadap Turnover Intention
Authors: David Muhammad , Solichin Much. Riyadus
Published: October 2021

Penelitian ini bertujuan untuk menguji dan menganalisis bagaimana pengaruh Kepemimpinan, Beban Kerja dan Kompensasi terhadap Turnover Intention   pada Karyawan Bagian Marketing Mataram Sakti Prembun Kabupaten Kebumen.  Populasi dalam penelitian ini adalah karyawan bagian marketing Mataram Sakti Prembun kabupaten Kebumen yang berjumlah 35 orang. Teknik pengumpulan data dengan cara kuesioner. Analisis yang digunakan adalah Uji  Validitas, Uji Asumsi Klasik, Analisis Regresi Linear Berganda, dan Uji Hipotesis.  Alat bantu pengolahan data yang digunakan adalah SPSS for Windows versi 22.0. Hasil penelitian menunjukkan bahwa : (1) Kepemimpinan berpengaruh negatif dan signifikan terhadap Turnover Intention, (2) Beban Kerja berpengaruh positif dan signifikan terhadap  Turnover Intention, (3) Kompensasi berpengaruh negatif dan signifikan terhadap Turnover Intention, (4) Kepemimpinan, beban kerja, kompensasi secara bersama-sama berpengaruh terhadap Turnover Intention.
Bauman, Zygmunt. (2007). Los retos de la educación en la modernidad líquida. Gedisa.
Authors: Cruz Picón Pablo Emilio , Hernández Correa Lady Jazmmin
Published: October 2021

Reseña del texto "Los retos de la Educación en la modernidad líquida", de Zygmunt Bauman.
Giraldo Gutiérrez, F. L., Gaviria Restrepo, Y. E., Aristizabal Berrío, W. J., & Ortiz Clavijo, L. F. (2019). Pedagogía de la paz: escenarios de posacuerdo. Una mirada desde la Educación Superior. Instituto Tecnológico Metropolitano de Medellín.
Authors: Bolaños Rodas Richard Andrés , Mojica Sanabria María Juliana
Published: October 2021

Reseña del texto de "Giraldo Gutiérrez, F. L., Gaviria Restrepo, Y. E., Aristizabal Berrío, W. J., & Ortiz Clavijo, L. F. (2019). Pedagogía de la paz: escenarios de posacuerdo. Una mirada desde la Educación Superior. Instituto Tecnológico Metropolitano de Medellín.”donde se realiza un analisis del contendio y alcanse del libro frente a la situación actual, sus aportes y debates a que invita.
Design of Piezoelectric Tile for Energy Harvesting: Experimental Approach
Authors: Maani Miandoab Ehsan , Jafari Amir Hossein , Valipour Aref
Published: October 2021

The generation of electricity by renewable energies is an important need of today's society. Piezoelectric energy harvesting is one of these useful technologies which can generate electricity by applying external force on piezoelectric material. This study illustrates more power generation from piezoelectric tile by changing the situation of piezo discs and connect to proportional electrical circuit. Two different designs of piezoelectric tile are presented by performing experimental analyses. The experimental results showed that placing piezoelectric elements in a bending position leads to higher power generation in comparison with traditional flat positioning, which was approximately 78 times far superior. It is also revealed that by design of an electrical circuit, the tile can be advantageous for lighting in crowded sidewalks with required lighting time. The results of this paper can be beneficial in the design and fabrication of these tiles for different applications.