bluuebunny/crossref_metadata_2025 huggingface dataset:
A Study of Prognosis and Outcome of COVID-19-Infected Hypertensive Patients on Angiotensin-Converting Enzyme Inhibitors/Angiotensin Receptor Blockers
Authors: Bharath M. S. , Ravitej S. , Balgi Vandana , Urs M. C. Rakesh Raje , Apoorva C. S.
Published: May 2023

Background and Objective:

COVID-19 is a pandemic caused by the virus severe acute respiratory syndrome coronavirus-2. The mortality in susceptible populations with chronic pulmonary disease, cardiac ailments, kidney disease, diabetes, and hypertension is high. While the role of angiotensin-converting enzyme inhibitors (ACEi)/angiotensin receptor blockers (ARBs) in contracting novel coronavirus has clearly been elucidated, there remains uncertainty in the prognosis and outcome of COVID-19-infected patients on ACE inhibitors and ARBs. The current study was conducted to find whether these medications bore any significance in the prognosis and outcome of hypertensive patients with COVID-19 infection.

Materials and Methods:

This is a retrospective cohort study. We studied 96-admitted hypertensive patients with pneumonia due to COVID-19 in Krishna Rajendra Hospital at Mysore during April 2021. Patients were categorized into two groups based on antihypertensive treatment: (1) Those on ACEi/ARBs (n = 33) and (2) Those on non-ACEi/ARBs (n = 66). We analyzed the parameters such as duration of hypertension, comorbidities, mode of oxygen/pressure support delivery, duration of hospital stay, and mortality among the two groups.

Results:

65.6% of patients were on non-ACEi/ARBs, 10.4% on ACE inhibitors, and 24% on ARBs. Of the patients on non-ACEi/non-ARBs, 51% were on supplemental oxygen, 20.8% were on NIV, 6.3% were intubated, and 21.9% did not require oxygen. Of those on ACEi, 63.6% were on supplemental oxygen, 15.2% were on NIV, none were intubated, and 21.2% did not require oxygen. Of those on ARBs, 53.3% were on supplemental oxygen, 18.5% were on NIV, 5.4% were intubated, and 22.8% did not require oxygen. 62.5% of patients on non-ACEi/ARBs recovered, whereas 37.5% succumbed. 83.3% of patients on ACEi recovered, whereas 16.7% succumbed. 65.2% of patients on ARBs recovered, whereas 34.8% succumbed. There was no significant correlation between non-ACEi/ARBs, ACEi, and ARBs with duration of hypertension (P = 0.092), sex (P = 0.189), mode of oxygen/pressure support delivery (P = 0.313), ward/intensive care unit stay (P = 0.624), and the final outcome of the patient (P = 0.734).

Conclusion:

In the population studied, the use of ACEi/ARBs in COVID-positive hypertensives was not associated with adverse outcomes as compared to those on non-ACEi/non-ARBs.
Zolpidem Dependence with Withdrawal Seizures
Authors: Babu M. Suresh , Adarsh L. S. , Meghana B. S. , Babbar Pragya
Published: May 2023

Insomnia is a common medical problem with an inability of the patient to fall asleep or stay asleep at night, resulting in nonrefreshing or nonrestorative sleep. Zolpidem is frequently used in clinical practice for the treatment of insomnia. It is considered a safe drug for the management of insomnia by many physicians as it lacks dependence, amnesia, and has minimal disturbance of rapid eye movement (REM) sleep. Seizure is a rare and serious withdrawal symptom of zolpidem. Here, we report a patient on treatment with zolpidem for insomnia developing drug dependence with withdrawal seizures.
Immunoglobulin G4-related disease (IgG4-RD) manifestations in the head-and-neck: A narrative review with a focus on imaging
Authors: Shukla Shreya , Mahajan Abhishek , Padashetty Shubham , Agarwal Ujjwal , Vaish Richa , Patil Vijay M. , Noronha Vanita , Chaturvedi Pankaj , Patil Asawari , Menon Nandini , Prabhash Kumar
Published: May 2023

Immunoglobulin G4-related disease (IgG4-RD) is an autoimmune fibrosclerotic inflammatory condition with distinctive histopathological findings affecting various organ systems. The disease can be tumefactive or “mass-like” in morphology, or less commonly, infiltrative. Many historic and well-known disease entities are manifestations of IgG4-RD in different organs. Radiologists need to be aware of this multifaceted disorder and its systemic nature. We searched Pubmed and Embase using the keywords “head and neck,” “IgG4-related disease,” and “imaging.” We included the relevant review articles published in the English language from 1997 to 2021, whose major area of discussion was IgG4-RD manifestations in the head-and-neck. Filters applied for inclusion were: “full text,” “humans,” “English,” “cancer,” article type: “review,” “meta-analysis,” “systematic review,” and “guideline.” In this review article, we have discussed the wide spectrum of manifestations of this disease at different head-and-neck subsites to familiarize radiologists with this interesting disease entity.
Integrated Care for Type 1 Diabetes: The West Bengal Model
Authors: Ghosh Sujoy , Yasmin Masuma , Sen Kaushik , Goswami Soumik , Das Tapas C. , Swar Subir C. , Maisnam Indira , Chakraborty Partha P. , Paul Bobby , Mukhopadhyay Dipta K. , Mukhopadhyay Pradip
Published: May 2023

Introduction:

A structured dedicated health programme for Type 1 diabetes mellitus (T1DM) has been initiated in the state of West Bengal, India.

Aim:

The aim is to provide comprehensive healthcare to all children, adolescents and young adults living with T1DM, along with the provision of free supply of insulin, glucose measuring devices, blood glucose test strips, and other logistics. The strategic framework for programme implementation is to utilise the infrastructure and manpower of the already existing non-communicable disease (NCD) clinic under National Health Mission.

Methodology:

Establishing dedicated T1DM clinics in each district hospital by utilising existing healthcare delivery systems, intensive training and hand-holding of named human resources; providing comprehensive healthcare service and structured diabetes education to all T1DM patients; and building an electronic registry of patients are important components of the programme. T1DM clinics run once a week on the same day throughout the state. All T1DM patients are treated with the correct dose of insulin, both human regular insulin and glargine insulin. Patients are routinely monitored monthly to ensure good glycaemic control and prevent complications of the disease. Routine anthropometric examination and required laboratory investigations are conducted in the set-up of the already existing NCD clinic. Ongoing monitoring and evaluation of the T1DM programme are being conducted in terms of glycated haemoglobin (HbA1c) values, growth and development, complication rates, psychological well-being, quality of life, and direct and indirect expenditure incurred by families. Through this programme, any bottlenecks or gaps in service delivery will be identified and corrective measures will be adopted to ensure better health outcomes for those living with T1DM.
A case of thymoma presenting as pyrexia of unknown origin
Authors: Marwah Vikas , Choudhary Robin , Shrinath V , Paliwal Gourang
Published: May 2023

Pyrexia of unknown origin can be caused due to numerous infective and noninfective causes. It poses a diagnostic dilemma to the clinicians and requires a myriad of investigations for the confirmation of diagnosis. Thymomas are rare mediastinal tumors that present as anterior mediastinal mass; however, thymomas presenting as pyrexia of unknown origin has rarely been reported in the literature. We report an interesting case of a middle-aged male who presented as pyrexia of unknown origin due to thymoma.
Malignant recurrent orbital solitary fibrous tumor
Authors: Pol Jaydeep N. , Patil Dipti B. , Desai Sharad S. , Calcuttawala Adnan B.
Published: May 2023

Solitary fibrous tumor (SFT) is a rare mesenchymal tumor of fibroblastic origin commonly occurring in pleura. It can occur at many extrapleural sites but is rare in orbit. Most cases are benign and recurrence is not unusual in the head and neck and orbit and is usually due to incomplete surgical excision. However, malignant transformation (MT) in orbital SFT is extremely unusual. We present a case of orbital SFT in adult male who developed recurrence with MT eight years after initial surgical excision. He underwent left orbital exenteration. The recurrent tumor revealed features of malignancy with areas exhibiting morphology typical of SFT. The immunochemistry confirmed the diagnosis of SFT with MT. The patient was given adjuvant radiation and was disease free for the last 18 months. Identification of malignancy in orbital SFT is important for the patient to receive appropriate postoperative treatment, as seen in the present case.
Alopecia and Periodontitis: Exploring the connecting dots
Authors: Agrawal Jaya , Lal Nand , Singhal Rameshwari
Published: May 2023

Alopecia areata is a systemic disease with nonscarring hair loss from the scalp, face, or any part of the body. The disease with undetermined etiology and pathogenesis has a considerable impact on the social life of patients which gradually builds up stress and expedites further deterioration of their condition. Interestingly, in such patients, besides stress-relieving exercises and immunomodulators, well-timed dental assessment and prompt treatment have contributed to improving the prognosis of alopecia. This depicts an interrelationship between alopecia and oral foci of infections. Over the past few decades, periodontitis has remained to be one of the predominant forms of oral focus of infection for systemic diseases. The present review throws light on the role of stress and autoimmunity in establishing a possible correlation between alopecia and periodontitis. It is augmented with documented case reports, demanding a complete oral examination in patients with the unexplained origin of alopecia. An interdisciplinary approach is the need of the hour which can prevent the progression of both the diseases as well as other oral infections.
Simultaneous detection and evaluation of Prevotella intermedia, Prevotella nigrescens, Prevotella loescheii, and Prevotella melaninogenica in subgingival plaque samples of chronic periodontitis and healthy individuals through multiplex polymerase chain reaction
Authors: Kottrashetti Vijaylakshmi S , Bhat Kishore G , Kugaji Manohar S , Naik Sachita Shrikant , Tanakanti Praveen
Published: May 2023

Background:

Prevotella is a Gram-negative anaerobic bacilli. The phenotypic characteristics of the various species of Prevotella are similar, which often makes it difficult in routine differentiation and identification of all the species.

Aim:

The purpose of the study was to detect and compare presence of Prevotella intermedia, Prevotella nigrescens, Prevotella melaninogenica, and Prevotella
loescheii in subgingival plaque samples of chronic periodontitis and healthy individuals.

Materials and Methods:

Two hundred and thirty-six subjects were considered consisting of chronic periodontitis (128) and healthy (108) individuals. Subgingival plaque sample was collected in reduced transport fluid and analyzed. DNA extraction and polymerase chain reaction (PCR) were performed for genus Prevotella followed by positive samples were considered for the detection of selected species through multiplex PCR using specific primers.

Results:

Out of 236 samples, 94.1% were positive for genus Prevotella. Out of 222 cases P. nigrescens showed the highest number of cases positive (59.5%) followed by P. melaninogenica (57.2%), P. intermedia (55.4%), and P. loescheii (40.1%). Species were analyzed individually between chronic periodontitis and healthy, P. intermedia, P. nigrescens, and P. loescheii showed greater positivity in healthy compared to chronic periodontitis. Positivity for P. melaninogenica was high in chronic periodontitis compared to healthy.

Conclusion:

The number of positive cases for species, when correlated with clinical parameters showed an increase in mean score for all clinical parameters assessed, suggesting the presence of variation in the prevalence of Prevotella species and geographic variation do exist in oral microflora. Findings suggest that they can be normal commensals and opportunistic.
Intramarrow penetration synergized with advanced platelet-rich fibrin in periodontal regeneration: A randomized controlled trial
Authors: Sharma Parth , Manjunath Shiva R. G , Gummaluri Shiva Shankar , Kunche Lavanya
Published: May 2023

Background:

Intramarrow penetration (IMP) is one of the recent treatment protocol where decortication is performed to stimulate osteogenic cells. IMP improves the blood supply and the inherent osteogenic properties of the vital bone and has the advantages of minimal surgical invasion, time, and cost. Incorporation of IMP in the regeneration of periodontal defects is very scarce. Hence, the present study aimed to evaluate the involvement of IMP and advanced platelet-rich fibrin (A-PRF) in the regenerative outcomes in the treatment of intrabony defects.

Materials and Methods:

In the present randomized controlled trial, 20 periodontitis patients with 20 defects were randomly allotted into two groups: group I open flap debridement (OFD) and A-PRF, group II OFD, intramarrow debridement, and A-PRF. Clinical parameters recorded were plaque index (PI), gingival index (GI), and clinical attachment level (CAL) probing depth. Radiographic parameters were defect depth, defect resolution, and change in alveolar crest height. Values were tabulated and subjected to statistical analysis. Paired and unpaired t-tests were performed for intra and intergroup comparisons. P <0.05 was set as statistically significant.

Results:

Intragroup comparisons showed a significant reduction (P < 0.05) in probing pocket depth, GI, PI, gain in CAL, and greater bone fill in both the groups from baseline to 6 months postoperative. Intergroup comparisons were not statistically significant (P > 0.05).

Conclusion:

Within limitations, both treatment modalities stand good, but utilization of IMP along with A-PRF results in effective regenerative outcome in intrabony defects because of its stimulation of osteogenic properties.
Effectiveness of the use of platelet-rich fibrin associated with open flap debridement compared to open flap debridement alone for the treatment of periodontal intrabony defects: Overview of systematic reviews
Authors: Padrón-Molina Oswaldo J. , Parise-Vasco Juan Marcos , Zambrano-Achig Paula E. , Montesinos-Guevara Camila
Published: May 2023

In the recent years, platelet-rich fibrin (PRF) has gained importance in regenerative medicine due to its attributed tissue-inducing properties. However, it is still unclear whether there are benefits from using PRF with open flap debridement (OFD) for the treatment of intrabony defects compared to OFD alone. For this reason, in this study, we performed an overview of systematic reviews with Friendly Summaries of the Body of Evidence using Epistemonikos methodology on the use of PRF with OFD compared to OFD alone for the treatment of intrabony defects. We performed a systematic search in the Epistemonikos database. We extracted data from the included systematic reviews and reanalyzed the data of primary studies and generated a summary of the findings table. We used Review Manager (RevMan) v5.3 software and GRADEpro software for data analysis and data presentation. Eighteen systematic reviews were included after full-text screening, which had 16 clinical trials. Results were reported by the mean difference (MD); the following outcomes were analyzed: change in intrabony defect depth (MD: 1.37 mm more), change in radiographic bone defect filling (MD: 37.26% more), change in probing depth (MD: 1.22 mm more), change in clinical attachment level (MD: 1.32 mm more), and change in gingival margin level (MD: 0.31 more). We concluded that applying PRF with OFD to treat an intrabony defect has some clinical advantages compared to OFD alone.
Clinical and radiographic study of the use of cross-linked gelfoam matrix in the treatment of dehiscence-like defects in Stage III periodontitis
Authors: Elboraey Mohamed Omar , Gamal Sherouk Mohamed
Published: May 2023

Background:

This clinical study aimed to overcome the difficulty of graft fixation and limited blood supply for dehiscence defects regeneration by using a cross-linked gelfoam matrix jointly with collagen membrane and xenograft.

Materials and Methods:

The study included twenty dehiscence-like defects in maxillary anterior teeth with ≥4 mm facial bone loss and ≥5 mm clinical attachment loss (CAL) in patients suffering from Stage III periodontitis. Sites were treated with regenerative surgery using a cross-linked gelfoam matrix with glutaraldehyde, xenograft, and collagen membrane. The recorded parameters were: CAL, probing pocket depth (PPD), and radiographic three-dimensional (3D) volume for dehiscence-like defects (3D volume of facial bone defects) and 3D volume of interproximal defects using cone-beam radiographs. Data of these parameters were collected at both baseline and 6 months postsurgery. “Paired t-test” was used to assess the two variables.”

Results:

Both CAL and PPD showed statistically significant reductions and there was a significant bone gain at 6 months postsurgery in comparison to baseline (P ≤ 0.05).

Conclusion:

Using a cross-linked gelfoam matrix with glutaraldehyde in combination with xenograft and collagen membrane could enhance the outcome of periodontal regeneration, especially in the treatment of challenging dehiscence defects.
Intelligent Flink Framework Aided Real-Time Voltage Computing Systems in Autonomous and Controllable Environments
Authors: Yang Qiuyong , Huangfu Hancong , Wang Yongcai , Shao Yanning
Published: May 2023

Motivated by the progress in artificial intelligence such as deep learning and IoT networks, this paper presents an intelligent flink framework for real-time voltage computing systems in autonomous and controllable environments. The proposed framework employs machine learning algorithms to predict voltage values and adjust them in real-time to ensure the optimal performance of the power grid. The system is designed to be autonomous and controllable, enabling it to adapt to changing conditions and optimize its operation without human intervention. The paper also presents experimental results that demonstrate the effectiveness of the proposed framework in improving the accuracy and efficiency of voltage computing systems. Simulation results are provided to verify that the proposed intelligent flink framework can work well for real-time voltage computing systems in autonomous and controllable environments, compared with the conventional DRL and cross-entropy methods, in terms of convergence rate and estimation result. Overall, the intelligent flink framework presented in this paper has the potential to significantly improve the performance and reliability of power grids, leading to more efficient and sustainable energy systems.
Slope stability assessment of some waste rock dumps at a typical gold mine in Ghana
Authors: Sarpong S.O. , Olaleye B.M. , Kunkyin-Saadaari F. , Agyei G.
Published: May 2023

Mining results in both economic and uneconomic materials being generated. The uneconomic materials (wastes) are stacked in a convenient place for  further use or stored permanently as a slope or embankment. In Ghana, a typical gold mine set up dumping sites to accommodate the waste generated  from its operations. Samples were collected from three waste dumps and tested in the laboratory, and the parameters obtained were used as input for  2D model development. The Factor of Safety (FS) of the three waste dumps were determined using the Janbu Generalised slope stability analysis method.  Path and slope surface (circular and non-circular) search methods were used for the three cases. The FS for the waste dumps were determined and  ranged from 1.61-2.74, 1.49- 2.50 and 1.32-2.10 under dry, static and pseudo-static loading conditions, respectively. These values exceed the minimum  requirements of 1.1-1.5 for stability conditions. The geometry of the waste dumps, Suraw Waste Dump (SWD), is within the standard and hence, does not  require reshaping, while the slope angles for the remaining waste dumps, Tano Waste Dump (TWD) and Akoti Waste Dump (AWD) need to be reshaped to  achieve the proposed slope angle of 3H:1V (18.40 degrees) as stipulated in the mine’s Environmental Impact Statement (EIS).
The menace and mitigation of air pollution in the built environment: A review
Authors: Nnaji C.C. , Chibueze C. , Afangideh C.B.
Published: May 2023

Air pollution has become one of the leading causes of death globally. This paper investigates the causes as well as sources of air pollution in the indoor  and outdoor environment. It identifies anthropogenic activities related such as transportation and other activities involving the combustion of fossil fuel  as the major causes of air pollution. The several and diverse health implications of air pollution were highlighted. The dangerous nature of carbon  monoxide was x-rayed and the common indoor and outdoor sources were discussed. The risks of carbon monoxide poisoning from generator fumes and  vehicle exhaust were clearly enumerated. Particulate matter (PM10, PM2.5 and ultra fine PM) were clearly shown to be the major casue of chronic and  fatal respiratory and cardiovascular diseases. Indoor air quality, which is usually overlooked was brought to the fore and shown to be worse than outdoor  air quaility in some cases, especially where ventilation is poor. The inextricable link between air pollution and climate change was also  established. Mitigative measure such as policies/acts, replacement of fossil fuel with solar PVs, replacement of conventional vehicles with electric vehicles  and establishment of urban forests were discussed. Frequent and evenly distributed air quality monitoring, especially using android-enabled portable  devices was broached. Besides, policies and other global approaches, individuals must adopt personal protective measures to protect themselves from  the menace of air pollution.
Performance of black olive oil as permeability reducing admixture in concrete
Authors: Ogbo H.E. , Ugwu O.O.
Published: May 2023

The study is aimed at improving the permeability aspect of concrete durability. The main reason for black olive oil (BLO) as the choice material relies on its  inherent hydrophobic properties. The effect of BLO admixture on strength and permeability properties of concrete grade C30 was experimentally  examined. BLO was integrated into the fresh concrete mix at percentages of 0.3%, 0.5%, 0.7% and 1% by weight of cement content and a water-cement  ratio of 0.5 was used throughout the study. Compressive and flexural strength, permeability properties in terms of water adsorption, porosity, coefficient  of permeability and sorptivity of the concrete samples were investigated after curing in water at 3, 7, 28, 60, 90 and 180days hydration period. The BLO  test admixture acted as a workability improving admixture and air entraining admixture in the fresh concrete. The various water permeability parameters  of BLO-concrete samples were significantly improved for all the percentage inclusion of BLO. However, the mechanical strength properties of  concrete sample containing the admixture decreased steadily with increase in BLO content. The 28days compressive strength of 03%, 05%, 0.7% and  1% BLO concrete samples decreased approximately by 3%, 13%, 6% and 13% respectively.The adverse impact on the strength properties of BLO-concrete  mixes attributed to the effect of increased air content and workability induced by the BLO admixture can be compensated by reducing the water-cement ratio. The 0.3% BLO-concrete which exhibited the least reduction in strength and also meeting the design strength required for residential buildings is  considered the optimum content.
Modelling rework cost for TETFund building construction projects in Nigeria
Authors: Dandajeh M.A. , Ibrahim A.D. , Ibrahim Y.M. , Adogbo K.J. , Ahmadu H.A.
Published: May 2023

Accurate predictions of rework cost enable contractors to evaluate how successful their projects are likely to be, thus, improve their operations and  productivity. Studies have developed project scope-based and non-scopebased rework cost predictive models. However, researchers have criticized the  accuracy of these models because of their weaknesses in giving individualistic treatments to project scope-based and non- scope-based rework cost influencing factors. This study therefore aimed at developing rework cost predictive models that combine the synergistic effects of both project scope- based and non-scope-based rework cost factors. 440 sample size was drawn from 2,638 population of Tertiary Education Trust Fund (TETfund) building  projects constructed between 2009 to 2015. Data of 287 (65%) of 440 (sample size) of completed TETfund building projects on project scope factors as  well as the extent of influence of the non-scope factors on cost of rework in TETfund building projects was collected. Principal Component Analysis (PCA)  and Multiple Linear Regression (MLR) were used in developing an integrated rework cost predictive model. More accuracy was achieved in the integrated  model through the incorporation of impact of project scope and non-scope influencing factors into rework cost prediction model, this increased the  variability in cost of rework to R2 = 0.759 (75.9%), while errors in rework cost predictions reduced by as much as 9.75%.The model serve as useful tool  used to enhance accuracy of rework cost predictions for TETfund building contractors, thus reduce cost of rework for building construction projects.
Recruitment Behaviour in an African Meliponine Bee Species (hymenoptera, Apidae: Meliponini): Understanding Glandular Origin and Pheromonal Components
Authors: Bobadoye Bridget O. , Alamu Olaniyi T. , George-Onaho Jennifer A. , Ete John A. , Ayandokun Ayangbade E. , Agboola Ifeoluwa S. , Adeoye Olubusola T. , Adekola Popoola J.
Published: May 2023

Meliponine bees are speculated to use a variety of communication mechanisms to effectively recruit workers of a colony to collect sufficient amounts of food to nourish the entire nest population. Mechanisms used to convey such information include thoracic vibrations and trophallaxis within the nest; footprint secretions and pheromone marks deposited in the field, or a combination of these signals and cues. There have been numerous discrepancies about the origin of trail pheromone production from the head, thorax, abdomen and leg regions of meliponine bees. Because the glandular origin of pheromone marks deposited by African meliponine bee’s species has not yet been investigated, we first confirmed if these species actually carry out scent marking and recruitment behaviour at visited food sources. Secondly, we tested if either nasonov or tarsal gland secretions elicited trail-following behaviour in newly recruited bees by means of chemical and electro-physiological analyses as well as with bio-assays testing both natural extracts and synthetic pheromone compounds from both glands. Significant differences were observed in the foraging patterns of the four bee species on collected resources (nectar, pollen and water) as the synthetic compound, (E)-β-farnesene was significantly as attractive to foragers of the four species when compared to the natural nasonov gland extract. Our results showed a significantly higher proportion of foragers from the four species been attracted to food resources baited with natural extracts from their own glands and recruited additional foragers to such baited food sites.

Keywords:  Meliponine bee species, recruitment behaviour, nasonov glands, tarsal glands
DNA Barcoding Reveals Occurrence of Cardiocephaloides sp. (Digenea: Strigeidae) Infecting the Great Cormorant Phalacrocorax carbo (L. 1758) in Mwanza Gulf, Lake Victoria
Authors: Chibwana Fred D
Published: May 2023

Cormorants (Pelecaniformes) are widely distributed worldwide, occurring as coastal birds in inland waters and marine environments, and have been implicated in the transmission of some aquatic parasites. As such, the objective of the present work was to investigate the occurrence and morphological variations in Cardiocephaloides (Digenea: Strigeidae), parasites of the great cormorant Phalacrocorax carbo. The Cardiocephaloides specimens used for molecular analysis (DNA barcoding (cox1) region) were obtained from the intestines of the great cormorants collected from Mwanza Gulf in Lake Victoria. Morphological examination of Cardiocephaloides specimens showed the possible co-existence of four morphospecies belonging to the genus Cardiocephaloides. However, detailed analyses of the cox1 sequences, phylogeny and haplotypes revealed that all four morphospecies belonged to a single unknown species of Cardiocephaloides. This paper provides the first report on the great cormorant Phalacrocorax carbo, serving as the definitive host for Cardiocephaloides in freshwater systems. The findings also reveal that the diversity of Cardiocephaloides in Africa is higher than earlier reported. Moreover, it highlights the need for more research in Tanzania to divulge snail and fish species involved in the life cycles of digenean species occurring in birds and other vertebrates in aquatic environments.

Keywords: Digenean trematodes; Strigeidae; Phalacrocorax carbo; Cardiocephaloides; cox1
Breeding parameters and phenology of the Egyptian Vulture (Neophron percnopterus Linnaeus, 1758) in Bulgaria
Authors: Yordanov E.S.
Published: May 2023

No abstract.
Seismic anisotropy in the upper crust around the north segment of Xiaojiang faults in the SE margin of Tibetan Plateau
Authors: Wu Peng , Gao Yuan , Xu Lisheng
Published: May 2023

The Xiaojiang faults located in the SE margin of the Tibetan Plateau is a fault system of left-lateral strike-slip, striking NS, between the 2nd-order Sichuan-Yunnan block and the 1st-order South China block. The Xiaojiang faults and the surrounding areas are characterized by strong tectonic movements and intense seismic activities. Using seismic data from January 2013 to November 2020 recorded at the stations of the temporary QiaoJia seismic Array (QJ Array), deployed by the Institute of Geophysics, China Earthquake Administration, this study investigates the upper crustal anisotropy by the shear-wave splitting analysis on small local earthquakes, discusses the deformation patterns in the upper crust in the north segment of the Xiaojiang faults, evaluates the stress distribution in the study area, and analyzes its relationship with the regional tectonic structure. Adopting the data processing technique of shear-wave splitting, a total of 875 effective records were obtained at 50 stations. The mean direction of polarizations of fast shear-wave (PFS) is 162° ± 44° in the study areaand the mean normalized time-delay is 4.96 ± 2.38 ms/km. Based on the spatial distribution of the PFS and the regional geologic structure, the study area is divided into two zones: the zone N and the zone S. The PFS in the zone N is scattered, but the dominant PFS direction is in NNW, which is consistent with the direction of the regional maximum principal compressive stress. In the zone N, there are a few smaller local areas (i.e., subzones A, B, C, and D) in which the orientations of the PFS are quite different from the surrounding area. In the zone S, the dominant directions at most stations are in nearly NS, consistent with the strike of the Xiaojiang fault. It reveals the detailed spatial distribution of seismic anisotropy in the upper crust, as well as in situ principal compressive stress, indicating the influence of the regional stress, the complex tectonic environment, and maybe also the impact of the South China block. It also reveals that there also might be an upper-crust scale of tectonic line at near 26°20′N under Xiaojiang faults, which coincides with the north-south tectonic boundary in the lithospheric anisotropy.
Empfindsamkeitsarchitektur. Der »Hameau de la Reine« in Versailles
Authors: Vogel Felix
Published: May 2023

Der von Marie-Antoinette in Auftrag gegebene und zwischen 1783 und 1789 durch Richard Mique in Versailles erbaute Hameau de la Reine besteht aus einem um einen künstlichen Weiher angelegten Ensemble von zwölf Bauernhäusern. Die vermeintlich vernakuläre Anlage ist jedoch von einem Widerspruch gekennzeichnet: Manche der rustikalen Gebäude waren vom dort arbeitenden Personal bewohnt oder wurden für agrikulturelle Produktion genutzt, andere dienten lediglich dem höfischen Vergnügen. Der äußerliche Schmutz war aufgemalt, innen zeigte sich zum Teil eine opulente Ausstattung. Das Buch rekonstruiert die Funktions- und Nutzungsgeschichte der Gartenanlage anhand bislang nicht berücksichtigter Archivquellen. Zugleich erschließt es den Hameau de la Reine kulturwissenschaftlich, indem es ihn in den Horizont der sich herausbildenden Epoche der Empfindsamkeit einordnet. Dabei zeigen sich die Objekthaftigkeit von Architektur, der Status von »ausgestellten Körpern«, Nützlichkeit als ästhetische Kategorie oder die Frage nach der künstlichen Herstellung von »Natürlichkeit« als zentrale Themen, die weit über die »Sattelzeit« hinaus Bedeutung beanspruchen: Im Hameau de la Reine wird Authentizität zum ästhetischen Kalkül, dessen Spuren bis in die Gegenwart reichen.
PENYEMBUHAN DALAM PENEBUSAN KISTUS MENURUT YESAYA 53: 4 – 6
Authors: Wibowo Cahyono Budi
Published: May 2023

Banyak pengajar kelompok Karismatik cenderung memberikan bobot dan penekanan yang sama, yang berargumen dari pengalaman. Buku-buku mereka sering dipenuhi dengan klaim kesembuhan dan pembebasan yang sudah terjadi, tetapi juga ada bukti yang menyatakan  bahwa klaim ini tidak valid dan penyembuhannya dipertanyakan. Ada juga yang seolah sembuh setelah didoakan tetapi setelah pulang menjadi sakit lagi, maka kesembuhan disini hanyalah sugesti. Oleh karena itu, semua pengalaman harus tunduk pada otoritas Alkitab, seperti yang dikatakan Rasul Petrus dalam membandingkan Kitab Suci dengan pengalamannya tentang transfigurasi Kristus: “Yang terutama harus kamu ketahui, ialah bahwa nubuat-nubuat dalam Kitab Suci tidak boleh ditafsirkan menurut kehendak sendiri,..” (2Ptr. 1:20). Makalah ini ditulis dengan asumsi bahwa Alkitab memiliki arti tersendiri yang sesuai dengan teks tentang penyembuhan. Oleh karena itu apa pun yang bertentangan dengan interpretasi yang benar dari Alkitab harus ditolak. Maksud makalah ini adalah untuk menguji konsep tentang makna penyembuhan dalam penebusan Yesus Kristus melalui studi eksegetis dari Yesaya 53:4-6, yang dengan jelas tersirat bahwa dengan bilur-bilur-Nya kita menjadi sembuh menunjuk kepada eskatologi.
Cartografia escolar e a alfabetização cartográfica: concepções para o Ensino de Geografia
Authors: Silva Allanis , Alves Danisléo , Caetano Rodrigo , Dantas Sulivan
Published: May 2023

O presente trabalho surge no contexto dos estudos desenvolvidos no Grupo de Pesquisa, Ensino e Extensão de Alfabetização Geográfica (ALFAGEO) da Universidade Estadual do Ceará (UECE), vinculado ao Laboratório de Prática de Ensino de Geografia (LAPEGEO/UECE) a fim de contribuir com o desenvolvimento teórico através do levantamento bibliográfico dos (as) autores (as) que abordam sobre o tema apresentado. No texto, será tratado o histórico da cartografia no ensino geográfico brasileiro, o mapa como ferramenta técnica, metodológica e de linguagem para aprender Geografia, além do processo de alfabetização cartográfica como metodologia primordial ao ensino e aprendizagem da cartografia escolar. Essa pesquisa foi elaborada através do levantamento bibliográfico de obras que discutem a cartografia escolar no contexto da alfabetização cartográfica.
Overlap of some forms of functional pathology of organs of digestion in children
Authors: Latyshev Dmitry Y. , Lobanov Yuri F. , Strozenko Ludmila A. , Riemer Natalia K.
Published: May 2023

Introduction. In the adult population, a high prevalence of the gastroesophageal reflux disease (GERD) and irritable bowel syndrome (IBS) can vary from 3 to 79%. As for children, there are a few works on the overlap between functional dyspepsia and IBS, GERD and functional constipation.
Aim. To determine the prevalence of overlap of the GERD syndrome with irritable bowel syndrome and functional dyspepsia in school-age children.
Materials and methods. The study included ninety eight cases including 71 boy and 27 girls, aged of 7 to 17 years (mean age 11.4 ± 2.1 years) suffered from erosive GERD. The comparison group consisted of 30 patients (11 boys and 19 girls), of mean age of 12.7 ± 1.8 years without erosive GERD). The criterion for inclusion in the main group was the presence of erosive changes in the esophagus according to fibrogastroduodenoscopy, in the comparison group the — manifestation of heartburn, with occurrence, at least twice a week over the past three months and the absence of erosive changes in the esophagus according to fibrogastroduodenoscopy. The exclusion criterion was the presence of organic pathology with sides of the upper (peptic ulcer, etc.) and lower parts of the digestive tract (ulcerative colitis, Crohn’s disease, etc.)
Results. Every fourth GERD patient (25.8%) has an overlap with functional bowel diseases, while GERD is more often combined with IBS with diarrhea (15.6%) than IBS with constipation/functional constipation (10.2%). Overlap of IBS with postprandial distress syndrome is much less common — only in 7.0% of children.
Conclusion. School-age GERD children are characterized by frequent overlap with functional bowel diseases, the frequency of which reaches 25.8%. The combination of all three diseases (IBS, GERD and postprandial distress syndrome) was observed in 2.3% of cases. These patterns are typical for patients with both erosive and non-erosive forms of GERD.
Diagnosis and treatment of esophageal lung in a premature baby
Authors: Alhasov Abdumanap B. , Gurskaya Alexandra S. , Nakovkin Oleg N. , Kazakova Klavdiya A. , Bayazitov Rimir R. , Ratnikov Sergey A. , Akhmedova Dinara M. , Konovalenko Marina A. , Varichkina Mariya A. , Karnuta Inna V.
Published: May 2023

The esophageal lung is a rare congenital malformation of the foregut, characterized by the existence of the lung tissue, a segment of the lung, and the main bronchus between the esophagus and the part of respiratory system. Because of the rare occurrence of this defect, examples of the treatment of this disease can be found only in foreign literature, in Russian-language sources, there are no described cases of treatment of the esophageal lung. In this regard, the literature data was analyzed and there was presented, clinical picture, classification, diagnosis, and treatment of this defect, as well as a case from practical activities was carried out: diagnosis and treatment of a premature one month baby with an esophageal lung.
Characteristics and properties of Serratia marcescens isolated in bacteremia in children
Authors: Sadeeva Zulfirya Z. , Novikova Irina E. , Alyabyeva Natalya M. , Lazareva Anna V. , Samoilova Ekaterina A. , Karaseva Olga V. , Yanushkina Olga G. , Vershinina Marina G. , Fisenko Andrey P.
Published: May 2023

Introduction. Serratia marcescens is an opportunistic gram-negative microorganism, currently has been detected with increasing frequency in various clinical biomaterials from sick persons is the causative agent of nosocomial infections.

The aim of the work is to determine microbiological and clinical features of S. marcescens in bloodstream infections in children.

Materials and methods. Nineteen isolates of S. marcescens were isolated from blood cultures. Antibiotic sensitivity was determined by broth microdilution method. Carbapenemase gene were determined using real-time polymerase chain reaction. Biofilm formation was studied on abiotic surfaces using polystyreneplates. Population diversity was determined by multilocus genotypic analysis.

Results. Carbapenems, fosfomycin and biseptol showed the highest antimicrobial activity in vitro. Resistance to aminoglycosides, aztreonam, cefepime, and ticarcillin/clavulanate was over 50%. According to PCR data, only OXA-48 carbapenemases were found in 11% of isolates, NDM — in 5%, and a combination of carbapenemases — in 15%. Biofilms of moderate intensity were formed in 13 (68%) isolates, and weak biofilms — in 6 (32%). According to the genotypic analysis, a large proportion of isolates with multiple resistance were included in one group. All of them were singled out over one year from one department — perhaps there was a single source. In 3 cases, patients were diagnosed with sepsis, 1 of them had an unfavourable outcome. Bacteremia occurred on the 3rd day after the initial isolation of S. marcescens. An unfavourable outcome occurred on the 10th day of bacteremia. S. marcescens in this case had multiple resistance and a combination of resistance genes, also belonged to genotypic group I, which is often found in our work.

Conclusion. S. marcescens in bloodstream infections is a serious problem for pediatric patients. Natural resistance to polymyxins, as well as acquired resistance to carbapenems and aminoglycosides, cause particular alertness and attention to this microbial agent.
The importance of echocardiography in the instrumental diagnosis of pulmonary hypertension in children with bronchopulmonary dysplasia
Authors: Basargina Milana A. , Davydova Irina V. , Turko Khiba R. , Bondar Valeriya A. , Fisenko Andrey P. , Seliverstova Alina A.
Published: May 2023

Early detection of such a formidable complication of bronchopulmonary dysplasia (BPD) as pulmonary hypertension (PH) is an urgent problem in pediatrics. Echocardiography is currently recognized as the most accessible and non-invasive method for determining pressure in the pulmonary artery. Disorders of alveogenesis and angiogenesis of the vessels of the small circulatory circle in premature infants forming BPD require careful echocardiographic control with using additional analysis of changes in the systolic eccentricity index (EI) as a reliable marker of PH in BPD infants. To increase the information content, it is also necessary to expand the use of EchoCG data in combination with analysis of the blood content of B type natriuretic peptide or the N-terminal pro-B-type natriuretic peptide.
Reproductive outcomes in adolescent girls with inflammatory diseases of the pelvic organs
Authors: Adamyan Leila V. , Sibirskaya Elena V. , Sharkov Sergey M. , Kirillova Yuliya A. , Pivazyan Laura G. , Loshkareva Maria A. , Dzharullaeva Zaira U.
Published: May 2023

Introduction. Inflammatory diseases of the pelvic organs (IDPO) are common forms of pathology, which are often accompanied by serious complications.
Aim: to determine the leading reproductive outcomes in adolescent girls with IDPO.
Materials and methods. The review is based on the analysis of the features of the course of IDPO and the impact of their complications on the reproductive function of adolescent girls. A search was conducted in the PubMed and Cochrane Library databases with a depth of 5 years.
Results. It has been established that the highest incidence of IDPO in adolescent girls is at the age of 15–19 years due to the early onset of sexual activity, the lack of effective contraception and the presence of several frequently infected partners. Recurrent infections, chronic pelvic pain, purulent complications (salpingitis, pyosalpinx, tubo-ovarian abscess), ectopic pregnancy, premature birth, endometriosis and infertility are the leading outcomes of IDPO in adolescent girls. It was revealed that the absence of sexual activity does not exclude the occurrence of IDPO and its complications in girls. This is due to the state of immune protection against infectious pathogens in girls, and the qualitative and quantitative composition of the microbiota of the genital tract. Therefore, it is so necessary to manage and conduct a wide screening of adolescents for the presence of sexually transmitted infections to prevent their negative impact on the fertility of young males and females, and effective training of adolescents on all significant issues of reproductive health.
Changes in the microbiota of the upper airways and intestine in the treatment of acute respiratory infections in preschool children
Authors: Kurdyukova Tatiana I. , Krasnorutskaya Olga N. , Bugrimov Daniil Yu. , Shevtsov Artem N.
Published: May 2023

Introduction. The microbiota of the upper airways and intestine in preschool children is directly involved in protecting the growing body from acute respiratory infections (ARI), which are the most common infections in children, about 65% of them turn into recurrent respiratory infections (RRI). Aim. To establish changes in the microbiota of the upper airways and intestine in the treatment of ARI in preschool children.
Materials and methods. The study involved sixty 1–6 year (Me = 3.38 years) frequently ill children. They were divided into 3 groups depending on the chosen treatment lasting 90 days. Children of group 1 (n = 20) underwent nutrition correction. Children of group 2 (n = 20) received additional probiotics. Children of group 3 (n = 20) received both nutritional correction and probiotics at the prescribed doses. Before and after treatment, the composition of the microbiota of the oropharyngeal zone and intestine was determined by genetic sequencing of the V3–V4 region of the 16S ribosomal RNA gene, followed by bioinformatic analysis.
Results. Significant differences were found mainly in the relative content of Firmicutes in the microbiota of patients treated. The content of Firmicutes in the microbiota of children receiving probiotics against the background of nutrition correction (30%) was significantly higher than in patients with nutrition correction (26.91%) and in children receiving only probiotics (25.95%). In patients of different groups, after treatment, a decrease in the content of Proteobacteria in the microbiota of the oropharyngeal zone was revealed. A significant decrease in the relative content of Bacteroidota (by more than 3 times) in 95% of patients, and a decrease in Proteobacteria (by more than 4.5 times) in 100% of patients was also found in the intestinal microbiota of group 3 patients treated with probiotics. In addition, there was a significant increase in the Firmicutes microbiota from 21.97% to 30.07% in 85% of patients, and an increase in the content of Actinobacteriota from 1.9% to 5.7% in 95% of patients. The relative content of undifferentiated microbiota after therapy was also significantly higher (70.08%) than before treatment (58.40%) in 85% of patients.
Enzo Traverso, Revolución. Una historia intelectual (2022)
Authors: López Cantera Mercedes
Published: May 2023

Reseña de Enzo Traverso, Revolución. Una historia intelectual, Buenos Aires, FCE, 2022, 615 pgs.
LESÕES DO NERVO LINGUAL EM CIRURGIA ORAL
Authors: Salgado Abel , Vinha Ana , Guedes Rafael
Published: May 2023

O nervo lingual é um dos nervos mais importantes na cavidade oral e com frequência é lesado durante alguns procedimentos de cirurgia oral. Devido à sua localização e possíveis variações anatómicas, alguns atos cirúrgicos que englobam a sua região podem tornar-se complexos e decorrer em complicações intra e pós-operatórias, nomeadamente lesões nervosas. Entre as diversas causas dessas lesões citam-se técnicas anestésicas incorretas, traumas de tecido duro e mole, sobretudo do retalho lingual, e reabilitações fixas implanto-suportadas. Este trabalho tem como principal objetivo ajudar os Médicos Dentistas no esclarecimento de como evitar e/ou resolver a maioria dessas complicações. A partir de uma pesquisa bibliográfica exaustiva, este trabalho foca aspetos como a frequência da ocorrência e grau de severidade das lesões do nervo lingual bem como formas mais comuns de as tratar. As modificações neurosensoriais consequentes de complicações relacionadas com tratamentos odontológicos são uma crescente preocupação dos Médicos Dentistas e, por isso, no presente trabalho serão focados alguns exemplos, nomeadamente a exodontia de terceiros molares, como um dos procedimentos mais frequentemente responsável pelo elevado número de lesões do nervo lingual. Face ao exposto, um bom planeamento pré-cirúrgico é fundamental, devendo o Médico Dentista recolher o máximo de informação possível, dadas as complicações inerentes inclusive no que respeita a modificações sensitivas na região orofacial que, em último caso, podem interferir de forma irreversível na fala, na mastigação e consequentemente nas interações sociais do paciente.