bluuebunny/crossref_metadata_2025 huggingface dataset:
Caco-2 cells monolayer as an in-vitro model for probiotic strain translocation
Authors: Fatmawati Ni Nengah Dwi , Goto Kazuyoshi , Mayura I Putu Bayu , Nocianitri Komang Ayu , Ramona Yan , Sakaguchi Masakiyo , Matsushita Osamu , Sujaya I Nengah
Published: November 2020

Background: Caco-2 cells monolayer is one of invitro models to evaluate the translocation capacity of Lactobacillus spp probioticstrains. The translocation is influenced by mucosa permeability of enterocytes as shown by increasing transepithelial resistance (TER) and formation of tight junction proteins. The pore size of the supported permeable membrane used in in vitro assay was one of the crucial factors in performing bacterial translocation assay. Almost no study has been conducted using Caco-2 cells monolayer grown on 8-Î¼m pore size polycarbonate membrane for evaluating probiotics translocation. Therefore this study aimed to determine whether the Caco-2 cells monolayer model was suitable as an in vitro translocation model.Methods: Caco-2 cells monolayer was seeded onto 8-Î¼m collagen-coated polycarbonate membrane insert TranswellÂ®. Differentiation of Caco-2 cells was detected by measuring the TER, while the ZO-1 protein (the tight junction proteins) was detected by immunofluorescence. H2O2 was used as a tight junction disruptive agent. Data were analyzed using SPSS version 23 software to compare the mean of TER measurement between untreated and H2O2-treated Caco-2 cells monolayer.Results: The result showed that the TER of Caco-2 cells monolayer was gradually increasing until day 14, reaching more than 800 ohm.cm2. Furthermore, the ZO-1 protein was successfully detected, indicated the tight junction formation. Â TER value of H2O2-treated cells showed significantly lower than that of untreated cells (P<0.05), indicating a disturbance of cells monolayer integrity. Lactobacillus rhamnosus FBB81 was used for validating the translocation. There was no translocation observed; however, translocation was observed in H2O2-treated cells.Conclusion: Altogether suggests that Caco-2 cells grown on 8 Î¼m-pore size permeable filters could be considered as a suitable in vitro model for probiotics strains translocation.
Diabetes mellitus control among elderly patients at geriatric polyclinic of Karangasem District Hospital, Bali, Indonesia: a preliminary study
Authors: Dwipayanti Ni Made Ayu , Nariata I Wayan , Aryana I Gusti Putu Suka
Published: November 2020

Background: The increasing number of elderly populations also increases the number of chronic degenerative diseases, including diabetes mellitus (DM). Therefore, diabetes control is needed to prevent various complications and improve the health quality of the elderly patient. This study aims to obtain preliminary information about diabetes control in elderly patients in the geriatric clinic of Karangasem District Hospital to provide appropriate management to improve diabetes control.Method: This research is a cross-sectional study and consecutive sampling of 46 DM patients who seek treatment at the geriatric clinic of Karangasem District Hospital in the period May-July 2019. Inclusion criteria were DM patients aged â‰¥60 years. We exclude diabetes person with acute infection and end-stage renal disease. The criteria for DM control used in this study is body mass index (BMI), systolic blood pressure (SBP), diastolic blood pressure (DBP), fasting plasma glucose (FPG), postprandial glucose (PPG), and HbA1c levels. Data were analyzed using SPSS version 25 for Windows and depicted descriptively. Results: Among 46 samples, there were 23 (50.0%) male and 23 (50.0%) female enrolled in this study. We find median of each, BMI was 23.2856 kg/m2, SBP 120 mmHg, DBP 70mmHg, 153.5 mg/dl for FPG, 238 mg/dl for PPG, and 7.8% for HbA1c. In this study, patients who met target of diabetes control is 34.8% for BMI, 53.8% for SBP, 76.9% for DBP, 43.5% for FPG, 17.4% PPG, and 28.3 % for HbA1c levels.Â Conclusion: In this study, it was found that DM control in elderly patients in our Hospital is not optimal on the parameters of BMI, SBP, DBP, FPG, PPG, and HbA1c levels. Better results were obtained in systolic and diastolic blood pressure control.
Influence of baby massage stimulation on the improvement of nutritional status, IGF-1, and cortisol level on undernourished infant
Authors: Sudarmi Sudarmi , Sukrama I Dewa Made , Sutirtayasa I Wayan Putu , Weta I Wayan , Irianto Irianto
Published: November 2020

Aim: This study aims to prove the effect of infant massage stimulation on the improvement of vagal activity and neurological effects (HPA axis) in infants with 6-12 months of nutrition including increased nutritional status, insulin-like growth factor 1 (IGF-1) and decreased cortisol.Method: The design method used for this study was a quasi-experimental with randomized pre-test and post-test control group design. Samples in this study were infants aged 6-12 with undernutrition status as many as 24 person as an intervention group (infant massage interventions and complementary feeding) and 24 people in the control group (provision of supplementary feeding). Infant massage interventions carried out for 3 months. Data collected included body weight, IGF-1 level, and Cortisol.Results: Effective infant massage improves nutritional status (p = 0.035) / (pâ‰¤0.05), increases IGF-1 levels (p = 0.002) or (p <0.05), and decreases cortisol levels (p = 0.022) / (p <0.05).Conclusion: Infant massage stimulation increases body weight, IGF-1 level, and reduces cortisol in undernourished infants aged 6-24 months. It is recommended for every mother to apply baby massage stimulation for alternative treatments to improve the nutritional status of infants who are undernourished.
Correlation of neutrophils lymphocytes ratio with femur muscle damage due to acute limb ischemia in white Wistar rats
Authors: Habibie Yopie Afriandi , Purnomo Avisenna Gatot
Published: November 2020

Background: Acute limb ischemia (ALI) is a sudden decrease in limb perfusion that threatens limb viability and requires urgent evaluation and management. Assessment determines whether the limb is viable or irreversibly damaged. Neutrophil-lymphocyte ratio (NLR) is a useful marker for cardiovascular disease to delineate the prognosis. Endothelial dysfunctions related to atherosclerotic plaques are usually associated with states of neutrophilia together with lymphopenia processes.Methods: This study was a post-test only control group performed on Wistar strain white rats. Thirty rats were divided into 5 groups, Control group (K), treatment group one (P1) examined NLR and femoral muscle tissue after 3 hours of ALI, P2 after 4 hours of ALI, P3 after 5 hours of ALI and P4 after 6 hours of ALI. Muscle tissue was histologically examined.Â Results: The duration of ALI increases the NLR value in Wistar strain white rats, the NLR value examined 6 hours after the rats experienced ALI increased significantly compared with the NLR values examined in the control group, the group examined 3 hours, 4 hours and 5 hours after the rats had ALI (p = 0.004). Necrotic muscle tissue very strongly correlated with the duration of ALI (r = 0.860, p<0.001). NLR value is strongly correlated with muscle tissue damage (r = 0.634, p<0.001).Â Conclusion: The duration of ALI increases the NLR value in wistar strain white rats, NLR values increased significantly after 6 hours of ALI. Necrotic muscle tissue occurs after six hours of ALI. NLR value is strongly correlated with muscle tissue damage. Revascularization must be done within 6 hours to prevent permanent damage.Â Â
Factors influencing sperm retrieval rate by Microdissection Testicular Sperm Extraction (mTESE) in non-obstructive azoospermia cases: a literature review
Authors: Sabudi I Made Nugraha Gunamanta
Published: November 2020

Background:Â Non-Obstructive Azoospermia (NOA) had dominating 60% of all azoospermia cases. Sperm Retrieval Techniques (SRT) continued with Intra-Cytoplasmic Sperm Injection (ICSI) are therapy modalities helping infertile azoospermia to be fertile. There are some options of SRT such as PESA, MESA, TESE, TESA and microdissection-TESE (mTESE) to collect sperm from azoospermia cases. This study aims to evaluate some factors influencing sperm retrieval rate by mTESE in non-obstructive azoospermia cases.Method:Â The data collection for eligible articles were conducted from 2011 to 2019. Different database and manual search methods were used to find the topic-related articles, particularly in some factors influencing the sperm retrieval rate of mTESE in NOA cases. A total of 21 relevant kinds of literature were studied regarding some factors that might be increasing or decreasing of sperm retrieval rate by mTESE procedure. However, four literature were elaborated further due to a similar approach to get the results.Results:Â A previous study from Saudi Arabia with 264 patients samples found significant different on testosterone level who had successful Sperm Retrieval Rate (SRR) 57.25%. SRR was related by several factors of testosterone, FSH, bilateral testis retrieval and seminiferous tubules diameter taken as the earliest study from India. Besides, taking bilateral testis sperm retrieval also had low SRR 14.4%, but serum FSH level was not influenced by increasing SRR. The previous study found a very weak correlation between FSH and SRR. A different study was conducted in Italy found that all NOA patient who undergone mTESE procedure found the Maturation Arrest (MA) has the significant higher success SRR until 67% after Sertoli Cell Only (SCO) syndrome and sclera-hyalinosis histology.Conclusion:Â SRR depends on some factors those influencing by hormonal baseline preoperative such as testosterone level and FSH serum level, technique and how mTESE done by the operator in mTESE procedure.
The relationship between age of menarche with striae among female students
Authors: Aryunisari Chyntia Giska , Putra Imam Budi , Jusuf Nelva K.
Published: November 2020

Background:Â Striae are harmless skin disorders, but can cause cosmetic and psychological concerns. The role of estrogen in reducing adhesion between collagen fibers can cause striae in stretch area. Menarche that occurs during puberty play a role in the increment of estrogen levels. Adolescents who had experienced menarche tend to have higher estrogen levels.Methods:Â  This was a cross-sectional study with total sampling method. 151 female students in Faculty of Medicine, Universitas Sumatera Utara were included and physical examination on the site of striae was done to confirm diagnosis. Age of menarche is classified as early (â‰¤11 y.o), normal (12-13 y.o) and late (â‰¥14 y.o). StudyÂ was conductedÂ after approval from the Ethics Committee Faculty of Medicine, Universitas Sumatera Utara.Results:Â Subjects in early menarche group were 84 (55.6%) subjects, normal were 56 (37.1%) subjects and late were 11 (7.3%) subjects. Median (11.0 y.o) and minimum-maximum age of menarche (9-16 y.o). Sites ofÂ striae were found mostly in thighs (66.9%), followed by buttocksÂ (11.8%), calvesÂ (7.4%), hips (6.6%), chest (3.7%), upper arms (2.2%) and breasts (1.4%). Subjects with early menarche were 84 subjects in which 78 with striae and 6 without striae. Subjects with normal and late menarche was 67 subjects with 35 having striae and 32 without striae. In this study, we found a significant correlation between age of menarche with striae (p <0.05).Conclusion:Â Early menarche can induce risk of striae in adolescents
Evaluation of bacterial infection of split-thickness skin grafts at the Korle Bu Teaching Hospital
Authors: Nsaful Kwesi Okumanin , Paintsil Albert B. , Dakubo Jonathan C. B. , Nsaful Josephine , Appiah-Labi Kwaku , Nartey Edmund
Published: November 2020

Background: Split skin grafts are frequently employed to provide biological cover for extensive wounds. The clinical outcome of skin grafts depends on a variety of factors of which infection is one of the most important. The intent of this study was to define the micro-organisms causing skin graft infections and failures at the National Reconstructive Plastic Surgery and Burns Centre (NRPSBC) at the Korle Bu Teaching Hospital (KBTH).Â Aim: The study assessed the extent to which bacterial infection of grafted wounds resulted in graft failure and subsequent re- grafting.Materials and Methods: The study was a longitudinal study conducted on the wards of the NRPSBC at the KBTH on patients with wounds who received split skin grafts. Wound swabs of discharging grafted wounds were inoculated into a Stuartsâ€™ transport medium to prevent desiccation and transported immediately to the microbiology laboratory for further processing.Results: Fifteen (20.8%) of the grafts failed to take. The incidence of infected grafted wounds was 79.2% (57). Infected grafted wounds that resulted in graft failure were 14 out of 57 infected wounds (24.6%). Pseudomonas aeruginosaÂ and OtherÂ PseudomonasÂ Species were identified as the bacteria frequently involved in graft failure at the NRPSBC.Conclusion: In this study, we found a graft failure rate of 20.8%. This was influenced by the bacterial load present in the graft bed.Â
Multifaceted rehabilitation strategies for ramsay hunt syndrome: a case report and a review of literature
Authors: Dewi Ni Made Ratih Purnama , Dharma Bagus Diva Indra , Silakarma I G N M Dedi , Samsarga Gede Wara
Published: November 2020

Background: Ramsay Hunt Syndrome (RHS) is a scarce diagnosis involving unilateral facial paralysis resulting from the reactivation of Varicella-Zoster Virus (VZV) infection in the past, which causes pain, asymmetrical facial expressions, and difficulty in speaking, eating and drinking. The most effective treatment is still debatable, and limited research is available. Rehabilitation program is considered as the core treatment that gives functional improvement. The aim of this case study is to present clinical findings in RHS and the rehabilitation program to maximize facial expression recovery.Case Description: A 59-year-old man came to rehabilitation medicine outpatient clinic two weeks after diagnosed as RHS, with complaints of fever; severe pain and rashes on the left side of the face; and ear discomfort on the same side. Physical examination revealed peripheral facial nerve palsy on the left side with drooping of the left eyelid, left end of the mouth, and difficulty in oral communication. Electroneuromyography (ENMG) examination showed axonal facial nerve paralysis on the left side. The patient was referred to the physiatrist and got rehabilitation program with neuromuscular electrical stimulation (NMES), facial massage and biofeedback exercise for facial muscle 3 times a week for 4 weeks.Discussion: After 4 weeks rehabilitation program, the patient showed improvement as House-Brackmann grades improved from a grade IV to a grade II; improvements in communication, facial symmetry at both rest and motion; significant improvement in experiencing pain. Conclusions: This study suggested that rehabilitation program with NMES, facial massage and biofeedback exercise are safe, efficacious and provide good outcomes in the treatment of Ramsay Hunt Syndrome.
Correlation of plasma vitamin d receptors with the severity of psoriasis vulgaris
Authors: Adiguna Made Swastika , Rusyati Luh Made Mas , Sudarsa Prima Sanjiwani Saraswati
Published: November 2020

Introduction: Psoriasis vulgaris is still a major problem in the field of dermatology. Until recently, the exact cause of psoriasis is still being debated. In recent years research has been carried out on vitamin D and its role in the immune system, especially in psoriasis. Vitamin D cannot be separated from the role of VDR. The study aims to evaluate correlation between VDR plasma levels and the severity of psoriasis vulgaris.Method: Study design using a cross-sectional design to determine the correlation of vitamin D levels in plasma with the severity of psoriasis vulgaris calculated using the Psoriasis Area and Severity Index (PASI) score.Result: This study included 47 study participants who had psoriasis vulgaris, consisting of 30 (63.8%) men and 17 (36.2%) women with a mean age of 44.66 years. The mean PASI score was 6.904, while the mean plasma VDR level was 30.328 ng/ml. Spearman correlation shows a strong negative correlation (r = - 0.979; p <0.001) between plasma VDR levels and PASI scores in psoriasis vulgaris patients.Conclusion: Vitamin D plays a role in regulating the growth and differentiation of keratinocytes and influences dendritic cells and T lymphocytes' immune function so that low vitamin D levels have essential implications in the pathogenesis of psoriasis vulgaris. In performing its function, vitamin D must bind to VDR and form a complex. In this study, it was found that there was a strong negative correlation between plasma VDR levels and PASI scores, so it can be concluded that low plasma VDR levels correlate with high degrees of psoriasis vulgaris severity and vice versa.
Potential development of turmeric extract nanoparticles as a topical anti-inflammatory agent
Authors: Suryawati Nyoman , Jawi I Made
Published: November 2020

Turmeric is the most commonly studied herbal ingredient because it has antioxidant, anti-inflammatory, antimicrobial, and anticancer activity. Considering that most inflammatory skin diseases are localized, it is considered that the topical application of turmeric extract can be beneficial because it has a local effect on the skin. The topical application of turmeric extract has limitations because the active ingredient content of curcumin (CUR) has poor solubility in water, low absorption, and rapid elimination of metabolites, which results in low bioavailability of the drug. Recent studies have focused more on nanoparticle formulations that can improve the stability and bioavailability of CUR.
The role of salivary biomarker as a diagnostic tool in oral cancer: a literature review
Authors: Prestiyanti Ni Made Ista
Published: November 2020

Background: Saliva is an informative biological fluid that has gained a lot of interest because of its physiologic diagnostic medium. The recent findings suggest that saliva could be used as a biomarker in diagnosing oral cancer. This study aims to elaborate further on the role of salivary biomarker as a diagnostic tool in oral cancer through literature review.Methods: A total of 44 relevant kinds of literature were studied regarding saliva and oral cancer. The data collection for eligible articles were conducted from 1997 to 2019. Different database and manual search methods were used to find the topic-related articles.Results: The study of saliva as a biological matrix has been identified as a new landmark initiative in search of a useful biomarker to diagnose oral cancer through proteomics and transcriptomics. Most oral cancers are oral squamous cell carcinoma. Using saliva for early oral cancer detection in the search for new clinical markers is a promising approach because of its noninvasive sampling and easy collection method. Identification of this salivary biomarker could help to screen patients at risk, predict disease outcome and effectively contribute to planning treatment strategies.Conclusion: proteomics and transcriptomics molecules on the saliva could be used as a biomarker in diagnosing oral cancer.
The determinant factors for Quality of Life (QOL) among children with Acute Lymphoblastic Leukemia (ALL) after induction phase at Sanglah General Hospital, Bali, Indonesia
Authors: Pasek Made Suadnyani , Ariawati Ketut , Arhana Bagus Ngurah Putu , Sidiartha I Gusti Lanang , Putra I Gusti Ngurah Sanjaya , Suwarba I Gusti Ngurah Made
Published: November 2020

Background: The Quality of Life (QOL) of patients with acute lymphoblastic leukemia (ALL) is important to be examined. Some determinant factors of the QOL for ALL patients are age, gender, ethnicity, nutritional status, level of income of parents, educational level of parents, and risk groups. This study aims to determine the quality of life score among children with ALL after the induction phase of chemotherapy and to determine determinant factors that are associated with the quality of life of children with ALL.Methods: An observational analytic study using a cross-sectional approach has been conducted among 38 ALL patients to assess the QOL after the induction phase chemotherapy at Sanglah General Hospital. The independent sample T test evaluated comparative values between independent factors. Multivariate analysis was assessed by the General Linear Model ANCOVA. Data were analyzed using SPSS version 20 for Windows.Results: Most of the respondents were age > 5 years old (55.3%), followed by the male (55.3%), well-nourished of nutritional status (55.3%), low parentsâ€™ educational status (55.3%), a high income of parents (52.6%), standard risk of stratification (52.6%), and non-Balinese ethnicity (55.3%). The mean score of QOL was 79.37Â±21.64. The results showed that male gender (95% CI: 2.35-16.04; p=0.010), high income of parents (95% CI: 3.17-22.05; p=0.010), standard risk factors (95% CI: 1.48-16.36; p = 0.020) were significantly related to the QOL of children with ALL.Conclusion: High-income parents, standard risk stratification, and male gender are determinant factors for higher QOL scores of children with ALL after the chemotherapy induction phase.
The low level of plasma vitamin C as a risk factor of preterm premature rupture of membrane
Authors: Sitepu Muhammad Freddy Candra , Suwiyoga Ketut , Kusuma Anak Agung Ngurah Jaya , Mayura I Gusti Putu Mayun , Darmayasa Made , Putra I Wayan Artana
Published: November 2020

Introduction: Preterm premature rupture of membrane (PPROM) still becomes a problem related with perinatal morbidity and mortality which is caused by multifactorial risk factor; especially strength of foetal membrane. Collagen is the main component of foetal membraneâ€™s extracellular matrix whereas plasma vitamin C roles as a collagen biosynthesis enzyme-dependent co-factor, down-regulator activity of MMP-1, MMP-2, and MMP-9 and also as antioxidant in remodelling and preventing structural damage extracellular matrix. The purpose of this study is to prove the low plasma level of vitamin C as a risk factor for PPROM on preterm pregnancy.Method: This study was an analytical observational unpaired case-control performed from March 23rd until August 23rd 2018 at Polyclinic and Emergency Unit of Obstetrics and Gynaecology Sanglah Central General Hospital, Buleleng General Hospital, Mangusada General Hospital, Sanjiwani General Hospital, Wangaya General Hospital, and Prodia Clinical Laboratory Denpasar. The samples were preterm pregnancy women with premature rupture of membrane (PROM) as a case group and without premature rupture of membrane as a control group. The samples were taken from peripheral venous blood and level of plasma vitamin C is measured by HPLC method. The data were analysed by SPSS for Windows 20.0 version program then presented as table and narrative.Result: Forty subjects were divided into 2 groups, 20 preterm pregnancy with PROM as a case group and 20 preterm pregnancy without PROM as a control group. Characteristic subject based on maternal age, gestational age, parity of both groups was 27.4 and 26.1 years old, 31 and 31 weeks, and also 1 and 1 time (p>0.05), not significantly different. The mean level of plasma vitamin C on case and control group were 3.90 Â± 1.61 dan 9.24 Â± 2.31 mg/L (p=0.001). On the case group the low level of plasma vitamin C was 51 times (OR= 51; CI 95% = 7.57â€“343.73; p=0,001) higher than the control group.Conclusion: The low level of plasma vitamin C is a risk factor of PPROM.
Vulnerability in Facing the Covid-19 Pandemic in the Light of Relational Trauma
Authors: Simonič Barbara , Gostečnik Christian , Repič Slavič Tanja , Poljak Lukek Saša , Cvetek Robert , Pate Tanja , Valenta Tanja
Published: November 2020

Coping with the COVID-19 pandemic has revealed different ways individuals react to frustrations they have experienced. Many times we have witnessed an increased level of aggression in interpersonal relationships and in the general social context. We find that there are some differences in coping and responding according to gender, with men showing a higher level of vulnerability and risk of inappropriate regulation and expression of anger when frustrated. To a certain extent, the answer to why this happens is provided by neuroscientific research, which shows that already at an early age, boys’ brains develop differently from girls’, as it takes more time to develop their stress-regulating mechanism; consequently, due to slower development, boys are more vulnerable to early stressful situations and have more problems with self-regulation of affective states at this early age. Together with the possibility of relational trauma in the family, to which many children are exposed from the earliest period of their lives and which plays an important role in providing a context for the development of affect regulation, that means that boys and men are even more vulnerable and sensitive to stress, aggression and trauma later in life. It makes sense to take these neuroscience findings into account when building an understanding of responses to stressful challenges, such as coping with a pandemic, as well as when planning appropriate models to help individuals cope with different types of stress.
COVID-19. A Catechetical-Experiential Reading
Authors: Sultana Carl-Mario
Published: November 2020

This article seeks to give a Christian understanding to the reality of COVID-19 which the world has gone through in the past months. This is done in a catechetical way by elaborating upon what truly transforms a lived event into an experience and into a Christian religious experience through a catechetical process. This implies seeking to understand any lived event by reflecting upon it and then applying the results of one’s reflection to one’s life. This theoretical framework is then applied to the reality of COVID-19 with the aim of rendering the lived event of the pandemic into a Christian religious experience which leaves a positive effect on the lives of believers through a catechetical process of understanding it in the light of the Word of God, and then applying the outcomes to one’s life afterwards.
Remote Teaching of Religious Education in Polish Schools as a Form of Evangelization and Catechesis during the Epidemic Threat
Authors: Chrzanowska Renata
Published: November 2020

This article discusses the current situation of the Church resulting from the epidemic threat of the coronavirus. It indicates how we can teach religious education online, using particular platforms and educational websites, as well as instant messengers and other internet services, to make them tools of catechesis and evangelization. The author emphasizes the spiritual contact of the faithful who, through the media, can participate in Holy Masses and receive the Spiritual Communion. She underlines the role of the proper use of mass media in the work of catechesis and evangelization. The author encourages people responsible for catechesis to be creative in the remote proclamation of the redemptive message, and to use all the available didactic resources and methods.
Professional Advancement of RE Teachers in the Context of the Challenges of the Information Society
Authors: Bilicka Beata
Published: November 2020

In the first years of political transformation in Poland starting in 1989, one of the crucial issues was the reform of education, including changes in the procedure of professional advancement for teachers. At that time, it was also important for the Catholic Church to restore Religious Education in schools, which returned to the state education system in the 1990–1991 school year. Since then, RE teachers have had the same rights and obligations as teachers of compulsory subjects and undergone the same professional advancement procedure. Twenty years have passed since the new procedure of career progression for teachers was introduced in Poland. Therefore the author of the article attempts to answer the following questions: To what extent does the procedure meet the challenges of the information society and in what direction should it evolve due to the rapid development of information and communication technology in the world?
Young People and Discernment of Vocations According to the Teachings of Saint John Paul II
Authors: Kamau Karanja Peter , Ikpe Remigius , Kitonga Daniel M.
Published: November 2020

Many young men and women are often confused when it comes to choosing their vocations and careers. According to Pope John Paul II in PastoresDaboVobis, “Each Christian vocation comes from God and is God’s gift. However, it is never bestowed outside of or independently of the Church. Instead it always comes about in the Church and through the Church a luminous and living reflection of the mystery of the Blessed Trinity.” What churches are doing with youth is commendable. Pope John Paul II earned the confidence of young people because he took them seriously. They sensed that he understood their concerns. He challenged them to give their lives to Christ. He appealed to their high ideals, inviting them to take a lead in the New Evangelization. Amidst the contemporary challenges facing young people, it would be appropriate to find ways of helping youth discern God’s call in their daily struggles. This implies learning to discern God’s voice hidden in the chaos of other worldly voices. The worldly allurements seem to have a great impact amongst youth. They therefore require some guidance from their parents and spiritual leaders in order for them to make the right decisions. This article looks at how Pope John Paul II treated the issue of vocational discernment among young people.
Pastoral Communities Based on a Model of Self-Help Groups as a Response of the Church to the Contemporary Social Changes
Authors: Wąchol Grzegorz
Published: November 2020

Dynamic changes in modern society generate new situations in the lives of believers, which require pastoral care. The Church should respond to the spiritual needs of all those in need, but with the decreasing number of ordained priests in Europe, organizational capacity in this part of the world is becoming increasingly limited. This article is an attempt to respond to the above problems and, using the example of the Catholic Church in Poland, shows the possibility of instilling a model of self-help groups for specialist pastoral care involving people experiencing life crises and wanting more intense religious development.
Objectivity as the Fruit of Authentic Subjectivity
Authors: Oko Dariusz
Published: November 2020

One of the most important problems of philosophy is the “critical problem”, the problem of bridge between the human mind and the world, the external reality. It is the question of relations between the subject and the object. The interesting solution for this problem is given by Bernard Lonergan SJ (1904–1984), one of the most important Catholic English-speaking thinkers of the twentieth century. It would be difficult to point to someone who influenced the American Catholic philosophy and theology from the inside out more than he did: that is why he is called the “American Rahner „. He tries to connect the great tradition of Thomism and Augustinianism and, on the other hand, classical and modern philosophy, German idealism and English Empiricism. At the heart of his thinking is the theory of the human mind. With the help of transcendental and phenomenological methods, Lonergan demonstrates that the mental structure of man consists of five levels: the empirical level, the intellectual level, the rational level, the responsible level and the level of religious experience, which together create a cumulative process that leads to knowledge and decision. The most important point here is he act of understanding, the insight, which always has a creative moment, especially on the second and third levels, as an effect of the subject’s work. The correct understanding of this moment enables a mediation between the empirical, rational and idealistic understanding of the knowledge process. Correct action on all levels, faithfulness to the nature of the subject, leads to truth – according to Lonergan’s very apt maxim: objectivity is the fruit of the authentic subjectivity.
Homo sum, humani nihil a me alienum puto – the imperative of the principle of humanitas in views on slavery derived from natural law. M.T. Cicero’s views on the subject of slavery and slaves
Authors: Nowak Olgierd Sebastian
Published: November 2020

The phenomenon of slavery existed throughout the entire period of the ancient world and met with interest from both Greek and Roman philosophers. Despite the emerging views of various philosophers criticizing slavery as a social phenomenon, no theory of slavery was formulated then. The philosopher who-, in both his works and correspondence, included numerous references to the situation of slaves and the institution of slavery was M.T. Cicero. Searching for humanism in Cicero’s views on the above-mentioned issue, attention was drawn to the principles of the Stoic doctrine, within which the concept of human freedom was formulated, and to the essence of natural law. These concepts made it possible to analyse the discussed problem in the context of the words of Terence Homo sum, humani nihil a me alienum puto. And as regards humanism in Cicero’s views, it is evident when he recognizes a human being in a slave; when he says that the principles of justice must be observed towards people from the lowest rank, which is the rank of slaves; when he firmly states that slavery is among the worst things that can happen to the human being. On the other hand, we see Cicero’s completely different views on slaves when he talks about punishing slaves, „keeping a tight rein on them,” or „destiny by nature for the best to rule others, and with great benefit for weaker beings”; also when he emphasizes his negative attitude towards the liberation of slaves. To conclude it should be emphasised that this characteristic feature of Cicero, namely his lack of uniformity of views on various philosophical doctrines, which we can also find in his views on slavery and the rank of slaves, does not prevent us from seeing a humanist in Cicero who, with his sense of justice, advocating the stoic doctrine and the principles of natural law, moved very slowly towards the stoic moral philosophy and all the ethical principles that Christianity would bring.
Accusation of Sin or Tolerance? From Christian Thought on Tolerance
Authors: Zwoliński Andrzej
Published: November 2020

The Catholic Church is very diverse. This is its beauty and value. However, this can also be a cause of trouble. Where there are differences, conflicts may also arise. Some are open and want dialogue and conversation with everyone, about everything and in every possible way. They are always on the border. They try to understand the world and reach out to it and read the teaching of the Church in a modern way. They advocate reform and radical change. Others are conservative – they care more about preserving the most valuable things in the Church along the way. They care about tradition. They trust the wisdom of time. They do not want to make sudden changes. They look at the past with respect and draw wisdom and inspiration from it, in order to act today. There are different sensitivities, different spiritualities, and even different needs. Can conflicts be avoided? It is certainly not easy and also requires mutual tolerance.
Repetition and not Parallelism as the Determinant of Poetry in the Hebrew Bible. A Case Study of Biblical Story of Creation (Gen 1)
Authors: Majewski Marcin
Published: November 2020

The article points to new research on the subject of poetics in the Bible and argues against the thesis that the basic indicator of poetry and poetic texts in the Bible is parallelism.According to the author, repetition is such an indicator. An analysis of the biblical story of creation of the world was used as the case study (Gen 1).
Lauda Sion, Salvatorem Sequence and its Polish Translations in the Source Songbooks
Authors: Garnczarski Stanisław
Published: November 2020

Research on the sequence Lauda Sion, Salvatorem dedicated to the Corpus Christi ceremony, allowed us to find and analyze over a dozen translations into Polish of this 13th century Latin pattern. It consists of 12 pairs of stanzas, with their parity – according to the poetics of the sequence – is emphasized by the conformity of a sound of the final verses of each pair of the stanza and the remaining verses are connected by adjoining rhymes, usually feminine, accurate, with aab + ccb scheme. We know most translators by name: Stanisław Grochowski, Jan Białobocki, Stanisław Serafin Jagodyński, Father Ignacy Hołowiński, Father Tadeusz Karyłowski, Jadwiga Gamska-Łempicka, Leopold Staff, several translations are anonymous. All Polish translations agree with the original on the content. However, differences appear in the form, structure of the poetic sequence, number of stanzas and in metrics. The common knowledge of the sequence Lauda Sion, Salvatorem, was probably the fruit of the great Eucharistic devotion in Poland, which was marked already in the 13th century, when the Church introduced the feast of Corpus Christi and lasted for the next centuries, up to the 20th century.
Results of the Combined Application of Various Schemes of Stimulation of Caviar Ovulation in Sterlet Producers Under Conditions of Regulated Systems
Authors: Tumenov Arthur , Dzhunusov Ahmediyar , Bakiyev Serik
Published: November 2020

The article presents the results of studies of schemes for stimulating ovulation of sturgeon caviar during rearing under conditions of regulated systems. Sturgeon (Acipenseridae) fish are characterized by high quality caviar and meat, and therefore are one of the main objects of cultivation in modern aquaculture. The achievement of sexual maturity of sturgeon fish when grown in facilities with a closed water supply cycle depends on the compliance with temperature and oxygen conditions, as well as species and the general physiological state of the fish itself. In modern aquaculture of sturgeon fish, the main species of cultivation are the following: beluga (Huso huso), Russian sturgeon (Acipenser gueldenstaedtii), Siberian sturgeon (Acipenser baerii), sterlet (Acipenser ruthenus) and their hybrids. Sterletт (Acipenser ruthenus) in comparison with other species of sturgeon fish reaches puberty at a much earlier date. The studies were carried out on the basis of LLP “Educational and Scientific Complex of Pilot Industrial Production of Aquaculture”. As it is known, pituitary injections and synthetic drugs activating the pituitary gland of sturgeons are used to stimulate producers. The study used sexually mature sterlet (Acipenser ruthenus) injected according to the combined stimulation schemes for carp pituitary gland and synthetic preparations “Surfagon”, “Nerestin-5”. To determine the effectiveness of using combined stimulation schemes for carp pituitary gland and synthetic preparations “Surfagon”, “Nerestin-5”, sterlet producers (Acipenser ruthenus) were divided into 3 groups of 20 individuals. As a result of the studies, the following fish-breeding and biological indicators of sterlet producers (Acipenser ruthenus) have been determined: weight of fish, weight of eggs obtained, as well as percentage of eggs to the total weight of fish.
Factors Affecting the Meaning in Life of Teachers
Authors: Suyatno  , Pambudi Dholina Inang , Amurdawati Ganis , Wantini  , Ningrum Mei Vita Romadon
Published: November 2020

This study aims to investigate the various models that affect the meaning in life of teachers. This is a quantitative study with data randomly obtained from a sample of 100 teachers at East Kalimantan, Indonesia. The results showed that self-actualization and self-transcendence are crucial factors which have an impact on the meaning in life of teachers. The policy makers need to utilize the results from this study to design various programs and training for the development of meaning in life of teachers.
Left ventricular global function index: prognostic value in patients with heart failure aged 60 years and older
Authors: Larina V. N. , Lunev V. I. , Alekhin M. N.
Published: November 2020

Left ventricular (LV) global function index (LVGFI) is a novel marker that incorporates the functional and structural characteristics of the LV.

Aim. To evaluate the prognostic value of LVGFI in outpatients with heart failure with preserved ejection fraction (HFpEF) aged 60 years and older.

Material and methods. The study included 78 patients (male, 42%) aged 74 (67-77) years with NYHA class II-III heart failure. LVGFI was defined as LV stroke volume/LV global volume х 100, where LV global volume was the sum of the LV mean cavity volume ((LV end-diastolic volume + LV end-systolic volume)/2) and myocardial volume (LV mass/ density).

Results. The median LVGFI was 21,7% (interquartile range 19,3 to 22,9%). Higher NYHA class of HF was associated with worse LVGFI:

class II HF was associated with LVGFI of 22,0 (20,3-23,1)%, class III HF — with 20,4 (17,5-22,4)%. During the 3—month (24-48) follow-up period, 15 (19,2%) patients died. Among patients with NYHA class II HF, 6 out of 61 (9,8%) died, with class III HF — 9 out of 17 (53,0%) (p<0,001). According to ROC analysis, the optimal LVGFI cut-off point for the prediction of an unfavorable prognosis in patients with HFpEF aged 60 years was ≤21,1% (p<0,001). The sensitivity was 73,3%, specificity — 70,0%. Patients with LVGFI ≤21,1% had significantly lower survival: among patients with LVGFI ≤21,1%, 11 out of 30 (36,7%) died; among those with LVGFI >21,1%, 4 out of 48 (8,3 %) died (p=0,016).

Conclusion. Higher NYHA class of HF was associated with worse LVGFI. Patients with lower LVGFI have significantly lower survival. The optimal LVGFI cut-off point for the prediction of an unfavorable prognosis in patients with HFrEF aged 60 years was <21,1%.
Estrutura e adequação dos processos de trabalhos no cuidado à obesidade na Atenção Básica brasileira
Authors: Brandão Ana Laura , Reis Erika Cardoso dos , Silva Cláudia Valéria Cardim da , Seixas Cristiane Marques , Casemiro Juliana Pereira
Published: November 2020

RESUMO Este artigo analisa a disponibilidade de estrutura e adequação do processo de trabalho no cuidado à obesidade na Atenção Básica (AB) no Brasil e regiões. Para tanto, realizou-se um estudo descritivo, transversal, de abordagem quantitativa a partir dos dados secundários do componente da avaliação externa disponíveis no PMAQ-AB, ciclo 2. A análise de dados partiu de três dimensões: vigilância alimentar e nutricional; coordenação do cuidado e assistência; e ações de promoção e educação em saúde. Os resultados revelam valores elevados no que se refere à disponibilidade de infraestrutura para cuidado à obesidade, embora nenhuma das variáveis atinja 100%. Quanto à adequação de processos de trabalho no cuidado à obesidade, no entanto, identificaram-se proporções mais reduzidas, indicando um desempenho incipiente nas três dimensões. As análises sugerem que o cuidado à obesidade se beneficiou do provimento de recursos para estruturação de Unidades Básicas de Saúde e que sustentar esse investimento na AB é relevante para a manutenção da estrutura e para a qualificação de processos de trabalho. O desenvolvimento de estudos avaliativos nesta temática pode cumprir papel importante para o planejamento de ações.
Uso de Práticas Integrativas e Complementares por idosos: Pesquisa Nacional de Saúde 2013
Authors: Marques Priscila de Paula , Francisco Priscila Maria Stolses Bergamo , Bacurau Aldiane Gomes de Macedo , Rodrigues Patrícia Silveira , Malta Deborah Carvalho , Barros Nelson Filice de
Published: November 2020

RESUMO O estudo teve por objetivo estimar a prevalência da realização de Práticas Integrativas e Complementares (PIC) e sua relação com doenças crônicas em idosos brasileiros. Estudo transversal de base populacional realizado com dados da Pesquisa Nacional de Saúde (PNS/2013; n=23.815). Estimaram-se a prevalência de realização de PIC e as frequências relativas das práticas referidas. Realizaram-se comparações entre proporções pelo teste de Rao-Scott com nível de significância de 5% e estimaram-se razões de prevalência para o uso das práticas integrativas e complementares, segundo doenças crônicas. O uso das PIC foi referido por 5,4% (IC95%:4,9-6,0) dos idosos. Entre estes, 62,6% relataram uso de plantas medicinais/fitoterapia; 22,2%, acupuntura; e 11,2%, homeopatia. Somente 6,7% realizaram o tratamento no SUS. Observou-se maior realização das práticas pelas mulheres e para todos os tratamentos considerados (p<0,001); naqueles com colesterol alto, artrite ou reumatismo, problema de coluna e depressão (p<0,05). Os resultados dimensionam o uso das PIC com dados de abrangência nacional, apontando para sua utilização no tratamento das diversas condições de saúde que acometem principalmente os idosos.
Resultados do tratamento das oclusões arteriais agudas de membros em hospital universitário – estudo retrospectivo
Authors: Teodoro Caroline , Bertanha Matheus , Girard Flavia Potsch Camara Mattos , Sobreira Marcone Lima , Yoshida Ricardo de Alvarenga , Moura Regina , Jaldin Rodrigo Gibin , Yoshida Winston Bonetti
Published: November 2020

Resumo Contexto As oclusões arteriais agudas (OAA) de membros vêm crescendo paralelemente com a longevidade da população. Objetivos O objetivo deste estudo foi avaliar fatores de risco, salvamento de membros e sobrevida dos pacientes com OAA tratados em instituição universitária. Métodos Este é um estudo coorte retrospectivo de pacientes consecutivos. Os desfechos incluíram: sucesso técnico, sintomas, comorbidades, categoria Rutherford, artérias acometidas, complicações pós-operatórias, taxa de salvamento de membros em 30 dias e óbitos. Resultados Avaliou-se 105 prontuários, havendo predomínio do sexo masculino (65,7%) e idade entre 46 a 91 anos. As etiologias identificadas foram trombóticas (54,3%), embólicas (35,2%) e indefinidas (10,5%). Cerca de dois terços apresentavam-se nas Categorias II e III de Rutherford. Os sintomas associados encontrados foram dor (97,1%), esfriamento (89,5%), palidez (64,7%), parestesias (44,7%), paralisias (30,5%), anestesias (21,9%), edema (21,9%) e cianose (15,2%); e as comorbidades associadas observadas foram hipertensão (65,0%), tabagismo (59,0%), arritmias (26,6%), dislipidemias (24,0%) e diabetes (23,8%). O segmento femoral superficial-poplíteo-distal foi o mais acometido (80%). A tromboembolectomia com cateter Fogarty foi realizada em 73,3% dos casos (81,0% nas embolias, 71,9% nas tromboses e 54,5% nos indefinidos), sendo isoladamente em 41 pacientes (39,05%), nos quais ocorreram 11 reoclusões, 20 amputações e 14 óbitos. A reoclusão arterial foi mais frequente nas tromboses (12,9%; p = 0,054). Até 30 dias após tratamento, o óbito total foi de 14,6% e a amputação maior foi de 19,8%, sendo menos frequente na Classe I Rutherford (p = 0,0179). Conclusão O tratamento da OAA feito prioritariamente por meio de tromboembolectomia com cateter Fogarty, isolado e/ou associado, proporcionou taxas de amputação e complicações compatíveis com as apresentadas na literatura e progressivamente menores nas categorias Rutherford menos avançadas.