bluuebunny/crossref_metadata_2025 huggingface dataset:
11-dehydrothromboxane B2 as a marker of acetylsalicylic acid resistance in patients with stable coronary artery disease
Authors: Lukianets K.Yu. , Pchelin I.Yu.
Published: September 2023

Introduction. Acetylsalicylic acid (ASA, aspirin) resistance is the inability to reduce thromboxane A2 synthesis in platelets and inhibit platelets activation and aggregation while taking ASA. Assessment of urinary 11-dehydrothromboxane B2 (11-dhTxB2) levels is one of the methods to identify aspirin resistance. Our research aimed to investigate whether urinary 11-dhTxB2 levels and other clinical and laboratory parameters are associated with a history of major adverse cardiovascular events (MACE) including myocardial infarction and ischaemic stroke in aspirin-treated patients with stable coronary artery disease. Patients and methods. In a cross-­sectional study we investigated 82 patients with stable coronary artery disease who took ASA at doses of 75–150 mg/day. We used the evaluation of the urinary 11-dhTxB2 levels standardized by creatinine as a method to identify aspirin resistance. Statistical analysis was performed using Mann-­Whitney U-test, ROC-analysis and multivariable logistic regression. Results. The medians of urinary 11-dehydrothromboxane B2 level in patients with and without MACE were 587.8 (Q1-Q3 512.8–800.3) pg/mg creatinine and 438.3 (Q1–Q3 337.6–577.9) pg/mg creatinine, respectively (p=0.001). The threshold level of urinary 11-dhTxB2, which predicted a high risk of aspirin resistance, was 521.1 pg/mg creatinine, and in 36 (43.9 %) patients the concentration of the 11-dhTxB2 exceeded this level. The regression model characterising the dependence of the presence of a history of MACE was constructed. It included platelet count, urinary levels of 11-dhTxB2 and the presence of type 2 diabetes. Sensitivity and specificity of the model were 55 % and 88.9 %, respectively. Conclusions. The results of the study demonstrate that the antiplatelet effect of aspirin is weaker in stable coronary artery disease patients with a history of MACE than in those without a history of MACE.
The Genesis of Dyspnea in Patients After COVID-19
Authors: Pozdnyakova T.D. , Sukhanov D.S. , Isakov V.A. , Korshunova A.L.
Published: September 2023

Post-COVID syndrome is an actual problem at the present time. The shortness of breath is one of the most common complaints in this group of patients. Dyspnea is one of the most significant disabling symptoms that negatively affect the quality of life of patients. The causes and mechanisms for the development of dyspnea in the post-COVID period are varied. In particular, one of the main causes of dyspnea is fibrosis-like and fibrous changes in the. Fatigue and / or muscle weakness, in particular of the respiratory muscles, can also be the cause of dyspnea. Direct SARS-CoV-2 infection of skeletal muscles, drug-induced myopathy, prolonged immobilization of hospitalized patients may also result in muscle weakness. Increased risks of thrombosis and pulmonary embolism (PE) after COVID-19, creating conditions for the development of chronic thromboembolic pulmonary hypertension, represent another factors for the development of shortness of breath. In patients with no abnormalities in blood gases or any other parameters that assess the functioning of the cardiovascular and respiratory systems, hyperventilation syndrome can be the cause of dyspnea. Thus, studying pathogenetic and molecular mechanisms of dyspnea development is an urgent problem, due to the need for specialists to choose the right tactics and select effective drugs and non-drug therapy for managing patients with this complaint.
Perancangan Apartemen Mahasiswa dengan Pendekatan Biophilic Design di Dramaga Bogor
Authors: Rahadiyan M. Aristyo , Bahar Yudi Nugraha
Published: September 2023

The existence of the Bogor Agricultural Institute (IPB), has become one of the factors of the fast development in Dramaga District of Bogor. Dramaga's development can be seen from the growth of vertical commercial and residential buildings. The growth of vertical housing is based on the purpose of marketing to IPB students. Along of recent years, IPB students have increased which makes the rental housing market compete to provide residential facilities as Student Apartments. The growth number of IPB students was not followed by the growth of rental housing. Based on the research results, there are students who carefully decide where they want to live along their study. The Biophilic Design approach, being able to participate helps connect activity users (residents, managers, and visitors) to be active in social interaction. Not only the relationship between humans but also as an access to the relationship between humans and nature. Biophilic Design can also reduce student stress caused by activities while studying. The method in this research is direct observation, literature review and design analysis with the results of concrete concepts. This research provides a solution for meeting the needs of housing with a typology of forms and spatial patterns that provide a sense of connection with nature.
The Effect of Gamma Value Alterations for Detecting Vertical Root Fracture in Indirect Digital Radiograph (an In-vitro Study)
Authors:   Department of Endodontics , Faculty of Dentistry, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran, Yazdizadeh Mohammad , Habibikia Ali ,   Department of Oral and Maxillofacial Radiology, Faculty of Dentistry, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran, Alavinejad Parnian ,   Department of Endodontics , Faculty of Dentistry, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran, Aghamirzadeh Amirmohammad ,   Department of Endodontics , Faculty of Dentistry, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
Published: September 2023

Background and Objectives Most digital imaging systems offer a variety of image processing techniques. Due to the importance of the accuracy of these images and their widespread application, this study aims to evaluate the detection of vertical root fracture (VRF) in indirect digital images by changing their gamma values. Subjects and Methods In this study, 23 extracted teeth were prepared as samples from dental clinics in Ahvaz, Iran. The radiographs were obtained from the samples before and after VRF induction. After root canal preparation, a very thin disc was used to divide the teeth into two halves in the buccal-lingual direction to create a VRF. The two halves were re-attached to each other and mounted in in molds filled with a mixture of plaster and sawdust. After processing the images by adjusting their gamma values using low, medium and high settings, the images were viewed by two radiologists for the presence or absence of VRF. Results In all three modes of gamma adjustment, the sensitivity, specificity and overall accuracy of images were high and there was no significant difference between the three modes. Conclusion The high gamma for digital images can used to as a filter to detect VRF. The images with medium and low gamma values are less helpful for detecting VRF
Synthesis of a Control System for a Longitudinal Feed Drive of a Lathe with Elastic Links Using a Non-Standard Intensity Generator
Authors:   Saint Petersburg Electrotechnical University, Belov M. P. , Kundyukov O. A. ,   Saint Petersburg Electrotechnical University, Korolev V. I. ,   Saint Petersburg State University of Industrial Technologies and Design
Published: September 2023

In the paper, the requirements for the feed drives of lathes are formed. The mathematical description of a two-mass system with elastic bonds is considered. In the MatLab/Simulink environment, a non-standard intensity generator was developed to control the considered object. A model of the automatic control system for the electric drive of the longitudinal feed of a lathe with elastic links has been developed using a non-standard intensity generator. The results of computer simulation were performed in the MatLab/Simulink environment to assess the performance of the intensity generator and the object model under control and perturbing influences. The transient characteristics of the system are presented and analyzed in terms of various parameters.
Hot Topics of Molecular and Cellular Biomechanics in 2022
Authors: Wang Guixue
Published: September 2023

The analysis of biomechanical characteristics plays an important role in mastering the technical characteristics of athletes, providing guidance for the formulation and prevention of sports injury training plans and providing theoretical support for research on injury prevention and stability control in the sports field. With the importance of data analysis, the application scope of artificial intelligence methods is more extensive. For example, intelligent training systems can be used for athletes’ personalized and professional training, real-time monitoring and feedback of training data, and further reduce the risk of sports injury. However, deep learning methods process a large number of medical images to identify and predict diseases such as cancer.
Artificial intelligence and automation in the migration governance of international students
Authors: Brunner Lisa , Tao Wei William
Published: September 2023

Artificial intelligence (AI) and automation are newly impacting the governance of international students, a temporary resident category significant for both direct economic contributions and the formation of a ‘pool’ of potential future immigrants in many immigrant-dependent countries. This paper focuses on tensions within Canada’s education-migration (‘edugration’) system as new technologies intersect with migration regimes, which in turn relate to broader issues of security, administrative burdens, migration governance, and border imperialism. Using an Accidental Ethnography (AccE) approach drawing from practitioner-based legal research, we discuss three themes: (1) ‘bots at the gate’ and the guise of AI’s objectivity; (2) a murky international edu-tech industry; and (3) the administrative burdens of digitalized application systems. We suggest that researchers, particularly in education, can benefit from the insights of immigration practitioners who often become aware of potential trends before those less embedded in the everyday negotiation of migration governance.
Dijital Çağda Aile: Ebeveynleriyle İlişkisi Çerçevesinde Gençlik ve Din
Authors: HABERLİ Mehmet
Published: September 2023

Dijital teknolojiler, dijital medya ile internet; günümüz toplumlarının gündelik yaşam, deneyim ve pratiklerini şekillendirerek, neredeyse dokunulmamış hiçbir alan bırakmamıştır. Toplumun en küçük birimi olan aile de dijital gelişmelerden etkilenen alanların başında gelmektedir. Bu süreçte dijital medya, yalnızca aile içi ve dışı iletişim biçimini değiştirmekle kalmamış, aynı zamanda ebeveyn-çocuk/genç ilişkisini de farklı düzey ve biçimlerde dönüştürmüştür. Dijital medya, bir yandan çocuk ve gençlere yeni sosyalleşme ile eğitim fırsatları sunarken; öte yandan aile içi ilişkilerde birtakım sorunların, pedagojik veya sosyal problemlerin ortaya çıkmasına yol açabilmektedir. Bu bağlamda gençlerin ailede gerçekleşen dini sosyalleşme süreçleri, dini eğitim biçimleri ile din algıları da değişime uğramaktadır. Buradan hareketle çalışma, dijital çağdaki ebeveyn-çocuk ilişkileri bağlamında, ergen ve genç bireylerin ailedeki dini sosyalleşme, din algısı ve dindarlık eğilimlerini ilgili literatüre dayanarak betimsel analiz yöntemiyle ele almayı amaçlamıştır. Çalışma sonucunda gerek dünyada gerekse Türkiye’de gençlerin dini bağlılık oranının yetişkinlere göre daha düşük olduğu görülürken, dijitalleşme ile din algısı arasında bir korelasyon olduğu saptanmıştır.
İmamların Erkeklik Anlayışı
Authors: ASLAN TURAN Esra
Published: September 2023

Türkiye’de toplumsal yapı erkek egemen değerlere göre biçimlenmiştir. Aileden başlayarak bütün kurumsal işleyiş ve düzenlemeler kadınları erkeklere göre daha aciz ve pasif gören davranış ve ilişki modelleri ortaya koymakta, erkek olmayı üstün ve ayrıcalıklı bir varoluş biçimi olarak benimsemektedir. Dini otoriteler ve söylemler de genellikle bu düzeni devam ettirmekte, çoğu yerde kadınları ikincil olmaya şartlandıran prensip ve kuralları onaylayarak pekiştirmektedir. Ortaya koydukları hükümlerin bağlayıcılığı itibariyle dinlerin bu hiyerarşik cinsiyet ayrımını normalleştirmesi, bunun kadınlar aleyhine yarattığı hak ihlalleri ve şiddetin olağanlaşmasında onların da payı olduğunu göstermektedir. Bu çalışmada özellikle cinsiyet ayrımını devam ettirme konusundaki yaygınlığı itibariyle halk dindarlığında önemli bir kurucu olan din görevlilerinin erkeklik anlayışı konu edilmektedir. Bu amaçla Diyarbakır merkez camilerinde imamlık yapmakta olan veya bu görevden emekli olmuş 30 imamla yüz yüze görüşmeler yapılmıştır.
Percepciones de los estudiantes de dos escuelas en el municipio de Paudalho/PE sobre el embarazo en la adolescencia
Authors: Silva Leticia Rodrigues da , Pereira Livia Maria Marques , Muniz Fausto José de Araújo , Palma Mariza Brandão , Soares Anísio Francisco
Published: September 2023

La adolescencia, un período de transición entre la infancia y la vida adulta, se refiere al momento en el que los individuos enfrentan cambios fisiológicos que se traducen también en cambios sociales con el despertar de la sexualidad. En este momento, los jóvenes exploran esta novedad lidiando con deseos románticos y sexuales, y a partir de esto, un descuido derivado de la falta de orientación puede impactar de diversas formas en la salud, el contexto social y el futuro del adolescente. La deserción escolar, las discriminaciones y las posibles consecuencias biológicas del embarazo son ejemplos de cómo la vida de los jóvenes puede verse afectada. De este modo, el presente estudio evaluó la percepción sobre el embarazo en la adolescencia y sus implicaciones. El estudio se realizó en dos escuelas públicas del municipio de Paudalho/PE, con la participación de 193 estudiantes de 15 a 19 años de edad, quienes respondieron cuestionarios sobre la temática estudiada. A partir de los datos obtenidos, se implementaron medidas educativas para guiar a los estudiantes sobre las conductas que deben adoptar para prevenir la transmisión de infecciones de transmisión sexual y embarazos no deseados.
Tributação progressiva como sanção política na prevenção de danos ambientais em busca de um desenvolvimento sustentável
Authors: Paz Flávia Piccinin , Gubert Marcelo Wordell
Published: September 2023

O artigo busca analisar a possibilidade de utilização da progressividade tributária como instrumento de sanção política na prevenção de danos ambientais para um desenvolvimento sustentável. A pesquisa aborda a função social do tributo e a possibilidade da progressividade tributária, bem como a possibilidade da sanção política como meio inibidor do dano ambiental através do princípio da prevenção. Na sequência, trata da análise da interferência do Estado no domínio econômico e o desenvolvimento sustentável. A escolha do tema se justifica diante da necessidade de buscar alternativas para efetivar o desenvolvimento de forma sustentável. Na condução desta pesquisa, adotou-se uma abordagem metodológica baseada no método dialético e dedutivo. A combinação desses métodos permitirá uma análise aprofundada e abrangente das interações complexas entre a progressividade tributária, a sanção política e a prevenção de danos ambientais para alcançar o desenvolvimento sustentável. A coleta de dados consistirá em revisão bibliográfica e documental de fontes primárias e secundárias relacionadas à progressividade tributária, sanção política, prevenção de danos ambientais e desenvolvimento sustentável. Após a coleta de dados, as informações serão organizadas e classificadas em categorias relevantes, considerando a função social do tributo, a progressividade tributária, os princípios da sanção política e da prevenção ambiental. Nessa etapa, busca-se identificar padrões e tendências relacionados à utilização de medidas tributárias como sanção política para promover ações preventivas em prol do desenvolvimento sustentável, serão exploradas as conexões e contradições entre a aplicação da progressividade tributária como sanção política e sua efetividade na prevenção de danos ambientais. Essa análise permitirá compreender as implicações da utilização dessa abordagem para alcançar um desenvolvimento sustentável mais efetivo. Conclui-se que a progressividade tributária se caracteriza como mais um fator a ser utilizado na busca de um desenvolvimento sustentável, em uma atuação preventiva dos danos ambientais.
The nth logarithm test for checking the absolute convergence of series
Authors: Morais Cláudio Marcelo
Published: September 2023

In this article, I present a test for absolute convergence of infinite numerical series using the concept of logarithm with base n indeterminate. Although there are cases where the current test is difficult to apply and others where inconclusive results may be obtained, it should be seen as an additional resource that mathematics students can use alongside the tests already available to verify the absolute convergence of a series.
FORMATION OF INSTITUTIONS FOR DECENTRALISATION OF ECONOMIC POWER
Authors:   Odessa I. I. Mechnikov National University, Gorniak Olga , Kotelevska Yana ,   Odessa I. I. Mechnikov National University
Published: September 2023

The article explores the establishment of decentralisation institutions of economic power in Ukraine, elucidating the core concept of economic power as an institution of contemporary socio-economic growth, its evolution, socio-economic implications and its connection with monopoly and property. Economic power implies the priority of the interests of all participants in the process of social production over the interests of the owner. It has been established that the interrelation of economic power, monopoly, ownership and management reveals the economic meaning of power and at the same time determines changes and directions of its development, one of which in modern conditions is its decentralisation. It is proved that the decentralisation of economic power involves the transfer of power, resources and responsibility. It is carried out through the formation of appropriate institutions that ensure its implementation and goes through the relevant stages. At the present stage, in the context of Russian aggression, the decentralisation of economic power is at the first (basic) stage, and institutions such as the amalgamated hromadas and starostats (an election-based public organisation consisting of group leaders) have been formed, which play an important role in socio-economic processes in the context of war, ensuring the vital activity of business entities and citizens of Ukraine.
MANAGING GREEN FINANCE RISKS IN UKRAINE
Authors:   State University of Trade and Economics, Mishchenko Svitlana , Naumenkova Svitlana ,   Taras Shevchenko National University of Kyiv, Mishchenko Volodymyr ,   Institute for Economics and Forecasting of the National Academy of Sciences of Ukraine
Published: September 2023

As many countries around the world are implementing sustainable development policies and seeking to finance environmental, climate and nature protection measures, the use of new financial instruments is becoming more widespread, with green loans and green bonds being the main ones. At the same time, their use exposes creditors and investors to significant financial risks that financial institutions and financial market regulators have not previously taken into account in their work. Therefore, the challenge is to develop new approaches to assessing and managing the risks of using green finance instruments to ensure sustainable development. On the basis of the recommendations and guidelines provided by international financial organisations, regulatory documents of central banks of OECD member countries for 2017–2022, and recommendations of the National Bank of Ukraine, the main areas of ensuring effective risk management of lending to green projects are determined, coefficients of the probability of default of the borrower in lending to green projects are calculated. A methodology has been developed to assess the concentration level of credit risks associated with green lending. The article proposes a system of liquidity ratios to secure collateral in green lending operations. A methodology has also been developed for calculating the adjusted interest rate of yield for green corporate bonds, taking into account inflation rates and the value of the established inflation target. Considerable attention is given to improving regulatory and supervisory measures by the central bank to manage the risks associated with the use of new green financial instruments. The proposed approaches can be used by domestic lenders and investors to improve the risk management of green finance in the post-war economic reconstruction period. The issues discussed in this paper are relevant to the discussion aimed at implementing balanced approaches to green finance risk management in the process of ensuring sustainable development in Ukraine.
PRACTICAL ASPECTS OF FORMING THE DESCRIPTIVE PART OF A BUSINESS PLAN FOR OBTAINING A GRANT FOR VETERANS AND THEIR FAMILIES IN THE EROBOTA PROGRAMME
Authors:   Lviv University of Trade and Economics, Kobelya-Zvir Maryana
Published: September 2023

The article discusses the main practical aspects of writing the descriptive part of a business plan in order to obtain funding for starting or developing a business from the eRobota programme for veterans and their family members. The article outlines the potential benefits of using the project approach and adhering to the grant writing guidelines when submitting proposals for the "eRobota" grant program. Additionally, it provides guidance on filling out a business plan using a recommended algorithm. Recommendations are given on the style of presentation of information in the descriptive part of the business plan. The main methods of the project approach are outlined, the use of which will ensure the creation of the descriptive part of the business plan for the competitiveness of the application for participation in the grant competition. Attention is focused on the need to take into account the essential conditions of the grantor, namely: the amount of own funds is applied to grants in the amount of 500,000 to 1,000,000 UAH and is 30% of the grant amount; the number of new employees under the terms of the grant programme depends on the grant amount: a grant of up to 250,000 UAH – one employee; from 250,000 UAH to 500,000 UAH – two employees; from 500,000 UAH to 1,000,000 UAH – four employees, two of whom are combatants and/or persons with disabilities caused by war. The basic rules for developing a high quality grant application are described, which must be strictly followed in order to have a chance of receiving non-repayable grant funding from the government's eRobota programme. An important method of the project approach is considered, namely, the "SMART" method for developing short- and medium-term goals of a business plan. Recommendations on the formation of sections are provided: "Business and Business Idea", "Market and Competition", "Sales and Marketing Plans". Demonstrated examples are provided for each subsection of the business plan. It is worth noting that the inability to form a business plan, particularly the descriptive part, poses an obstacle for potential grant recipients in attracting grants. It is crucial to use the project approach, adhere to the grantors' requirements and maintain the vertical logic of the project for the correct presentation of material in the descriptive part. It has been determined that the quality of the project proposal development is crucial in order to obtain nonrepayable grant assistance from donors.
INTERNATIONAL EXPERIENCE OF USING THE CLUSTER CONCEPT IN ENSURING ECONOMIC SECURITY OF UKRAINE
Authors:   Ivan Franko National University of Lviv, Struchok Nataliia , Viter Oleksandra ,   Ivan Franko National University of Lviv, Kylyn Oksana ,   Ivan Franko National University of Lviv
Published: September 2023

The article reveals the meaning of the cluster concept, outlines the positive effects of the development of the cluster concept as a form of business organisation for the economic security of the country. A general interpretation of the definition of a cluster as an association of geographically closely related enterprises, including enterprises that have a single goal in their activities and receive support from the state or local authorities. The main instruments and areas of cluster support in the national programmes of the countries of the international economic space have been identified. The main sources of financing cluster associations in the global business environment are identified. The creation of clusters as an organised system of information and technology diffusion makes it possible to quickly implement changes and modernise technologies due to their flexibility. The economic efficiency of clusters, which is implemented taking into account the determinant principles: the tendency to meet the needs of consumers at the highest level, the minimum number of hierarchical levels, as the cluster includes various enterprises that can solve most of the tasks of the customer, the existence of an integrated information system, which allows to concentrate on the performance of important tasks, the most flexible organisational structure. The obstacles in implementing the cluster concept and its consequences on the economic security of the nation have been outlined. The efficacy of clusters is justified by adhering to specific principles, including the following: the tendency to satisfy consumer needs at the highest level, the minimum number of hierarchical levels, the existence of an integrated information system, the fastest reaction to changes in the internal and external environment, adaptation to new conditions, a maximally flexible organisational structure, self-organisation at a high level, use of dynamic forms of competition with cooperation and collaboration prevailing over domination and acquisition. The Global Innovation Index 2021 highlighted the weight of the "state of cluster development" indicator as part of the business environment index. Furthermore, the paper outlines the place of Ukraine in the structure of the Global Innovation Index 2021.
ЗАБЕЗПЕЧЕННЯ РЕЗУЛЬТАТИВНОСТІ ОРГАНІЗАЦІЇ ПРИ ПЕРЕХОДІ НА ДИСТАНЦІЙНУ ФОРМУ ПРАЦІ
Authors: Прохоренко Олена , Брінь Павло , Ковшик Валентин
Published: September 2023

В останні роки використання дистанційної праці стало одним з головних викликів для менеджерів через безпрецедентну пандемію. Для багатьох українських організацій у 2022 році необхідність здійснення ще більш радикального переходу на віддалену працю була викликана російським вторгненням в Україну та пов'язаним з цим переміщенням населення. Перехід до нової форми роботи в умовах невизначеності, разом з чіткою потребою підтримувати та покращувати результативність, посилюють інтерес до цієї теми. Однією з найактуальніших проблем при цьому є забезпечення комфортних умов праці. Метою дослідження є вивчення очікувань та вимог працівників щодо дистанційної праці, порівняння цих вимог з потребами менеджменту і визначення напрямків вдосконалення роботи в цій сфері. Дослідження ґрунтується на аналізі емпіричних даних онлайн-опитування працівників та керівників організацій. Визначено потенціал для вдосконалення управління дистанційною роботою за рахунок технічного забезпечення, роз'яснення нових робочих процедур та навчання персоналу для роботи в нових умовах. Крім того, виявлено взаємозв'язок між потребами та вимогами працівників і такими факторами, як вік, стать та функціональні обов'язки. З практичної точки зору результати дослідження можуть бути використані менеджерами різних рівнів для кращого розуміння потреб працівників, розробки операційних стратегій та стратегій управління людськими ресурсами в сучасних умовах.
ПУБЛІЧНЕ УПРАВЛІННЯ ІНТЕГРАЦІЙНИМИ ПРОЦЕСАМИ ВНУТРІШНЬО ПЕРЕМІЩЕНИХ ОСІБ У ПРИЙМАЮЧІ ГРОМАДИ
Authors: Тихончук Леся , Боровик Марина
Published: September 2023

У статті розглянуто публічні механізми інтеграції внутрішньо переміщених осіб в приймаючі громади. Виокремлено основні аспекти успішної інтеграції внутрішньо переміщених осіб в громаді: забезпечення зайнятості, підтримка соціальних послуг, соціокультурна адаптація, підтримка соціального благополуччя, подолання дискримінації, міжкультурна взаємодія, участь у громадському житті, економічна підтримка і юридичний захист. Розглянуто та проаналізовано можливості для розвитку громади за участю внутрішньо переміщених осіб. Досліджено роль органів місцевого самоврядування в наданні не лише кризової допомоги, а й сприянні довгостроковій інтеграції переміщених осіб у місцеве життя. Досліджено механізми державного регулювання інтеграції внутрішньо переміщених осіб під час війни. Підсумовано, що розвиток громад та регіонів відбуватиметься при умові якісних інтеграційних процесів ВПО та ефективного публічного управління цими процесам за участю всіх учасників – громадян, громадських організацій, органів місцевого самоврядування, держави та іноземних партнерів.
СТАН ДЕРЖАВНОГО БОРГУ УКРАЇНИ В УМОВАХ ВОЄННОГО СТАНУ
Authors: Бей Сніжана , Головай Надія , Долюк Алла
Published: September 2023

У статті досліджено тенденції та динаміку зростання державного боргу України впродовж 2015-2022 рр. Метою даної роботи є дослідження стану державного боргу України в умовах воєнного стану та пошук шляхів його оптимізації. Здійснено аналіз стану державного боргу України до повномасштабного вторгнення рф на територію нашої держави і в період військових дій. Падіння економіки припадає на період початку агресії російських військ на сході України, окупації частини України та пандемії COVID-19. Встановлено, що накопичені проблеми у сфері управління державним боргом та військові дії, які розпочалися 24 лютого 2022 року, призвели до стрімкого зростання обсягу державного боргу в Україні. Отже, державний борг продовжуватиме зростати та потреба у борговому фінансуванні залишиться і в 2023-2024 рр Зосереджено увагу на важливості визначення стратегічних напрямів оптимізації державного боргу та пошуку більш ефективних рішень у цьому напрямку.
Penerapan Sertifikat pada Sistem Keamanan menggunakan Teknologi Blockchain
Authors: Sunarya Po Abas
Published: September 2023

Popularitas teknologi Blockchain telah banyak digunakan dalam aspek kehidupan di berbagai bidang dan industri. Karena sebelumnya teknologi blockchain digunakan sebagai crypto atau dikenal dengan mata uang digital yang telah berkembang ke arah teknologi dan digital berkembang pesat. Dimana penggunaan teknologi blockchain merupakan sebuah inovasi baru yang semakin berkembang dalam sistem keamanan data yang sesuai dengan perkembangan zaman dan menjadi salah satu teknologi modern dalam dunia pendidikan. Dalam hal ini penelitian akan memiliki menyajikan keterbaruan berupa implementasi teknologi Blockchain pada objek penelitian yaitu penyimpanan sertifikat tanpa keterlibatan pihak ketiga (Desentralisasi). sehingga sebagai solusi, pada penelitian ini akan menghadirkan aplikasi teknologi Blockchain dengan keunggulan yang diberikan adanya transparansi dan sifat yang desentralisasi untuk tujuan agar peneliti selanjutnya dapat menghasilkan inovasi baru dalam peningkatan keamanan data dan peningkatan kualitas teknologi yang dapat menghasilkan temuan baru pada sistem keamanan data yang lebih modern. Dalam menuju keberhasilan penelitian, metode yang digunakan adalah sampling yang akan memecahkan permasalahan dan solusi yang dihadirkan. Hasil dari penelitian yang didapatkan, penerapan teknologi blockchain dapat meningkatkan keamanan sertifikat yang telah diterapkan pada publikasi jurnal dengan nama abc. untuk meningkatkan keketatan perlindungan data sistem.
Nominal linkers in Central Kurdish (Ardalāni variety)
Authors: Kalami Sadaf
Published: September 2023

This chapter provides a description of noun phrases in the Ardalāni variety of Sorani Kurdish. In Ardalāni Kurdish, the surface word order within the Noun Phrase is head initial and post-nominal modifiers are linked to the head of the phrase by a linking element called Ezafe (Windfuhr 1989). We show that the realization of Ezafe is phonologically conditioned in Ardalāni, unlike other varieties of Kurdish. However, crucially, we show that in definite contexts, Ezafe obligatorily appears irrespective of the phonological context, and it takes a special definite form.
Adaptacja ekspatriantów akademickich na uczelniach zagranicznych –wyniki badań pilotażowych
Authors: Przytuła Sylwia
Published: September 2023

Celem artykułu jest przedstawienie procesu adaptacji akademickich ekspatriantów pod kątem adaptacji ogólnej, interakcji społecznych i warunków pracy. Pilotażowe badania jakościowe w formie wywiadów przeprowadzono z 13 naukowcami pracującymi na uczelniach zagranicznych w latach 2021–2022. Wyniki świadczą o pozytywnej adaptacji do życia w obcym kraju. Adaptacja do miejsca pracy opiera się na koleżeńskich relacjach, zaufaniu i autonomii. Adaptacja do lokalnych interakcji jest najtrudniejsza dla zagranicznych naukowców, a główną przeszkodą jest brak znajomości języka lokalnego.
Selection and Use of Antioxidants-radioprotectors in the Composition of Therapeutic Radiopharmaceuticals (Review)
Authors: Pavlenko E. P. , Larenkov A. A. , Mitrofanov Iu. A.
Published: September 2023

Introduction. The use of radiopharmaceuticals for targeted radionuclide therapy (TRT), the efficacy of which was established during clinical trials, is safe and effective for various pathological conditions, including cancer. The main feature of therapeutic radiopharmaceuticals (RPs) is the use of β–- and α-emitting radionuclides (RNs) in the finished dosage form (FD). Among the radionuclides used for radionuclide therapy, lutetium-177 is currently one of the most popular in clinical practice because of its chemical and nuclear characteristics. The list of RPs based on lutetium-177 is constantly expanding, and Lutathera® ([177Lu]Lu-DOTA-TATE) and Pluvicto™ ([177Lu]Lu-PSMA-617) have been approved for clinical use in several countries.

Text. Because of the high activity of RNs in a single dose of therapeutic RPs (up to 8 GBq in a monodose for 177Lu), ionizing radiation of the used RNs leads to a decrease in RPs quality owing to radiolytic degradation of the vector molecule. This leads to a decreased specific accumulation of radioactivity in the foci of pathology, reduced therapeutic effect, and potentially increases the risk of radiotoxicity to non-target organs and tissues. The degree and intensity of radiolytic degradation of the vector molecule and, consequently, the shelf life of RPs depend on many factors, among which the activity concentration of the radionuclide in the preparation, its half-life, and the energy of the emitted particles are the most important. To suppress the effects of radiolysis, various excipients with antioxidant (radioprotective) properties were introduced into the compositions of the finished dosage forms. Among the substances studied, the most popular were gentisic acid, ascorbic acid, and ethanol. In this work, the advantages and disadvantages of various antioxidants and their combinations used in therapeutic RPs were considered in lutetium-177 preparations.

Conclusion. Selection of the optimal composition of the dosage form is an urgent task, as it will ensure high-quality RPs both at the time of preparation and during the shelf life and delivery to the end user, which will greatly facilitate the use and centralized supply of therapeutic RPs. The necessity of creating a unified approach for the selection of antioxidants at the pharmaceutical development stage of radiopharmaceuticals is shown. For this purpose, an approach combining studies of radical reaction kinetics with studies of radiation-chemical yields of radiolysis products under identical or maximally similar conditions with subsequent verification of the stability of RPs dosage form seems to be very promising and has proven to be effective. In contrast, the empirical approach, which implies the selection of radioprotectors based on a direct study of their influence on the preservation of the level of radiochemical purity, is suboptimal because of the high market value of both radionuclides and non-radioactive precursors.
Effect of Physical Rehabilitation on Hemodynamic Status
Authors:   Ministry of Home Affairs Birch Grove health resort, Moscow, Grashchenkova АN , Grashchenkov DE ,   Ministry of Home Affairs Birch Grove health resort, Moscow, Puzin SN ,   Russian medical Academy of continuing professional education of Minzdrav of Russia, Moscow 3 Sechenovskiy University of Minzdrav of Russia, Moscow 4 Federal state budgetary scientific institution "Federal scientific and clinical center for resuscitation and rehabilitation", Moscow region, Russia, Bogova ОТ ,   Russian medical Academy of continuing professional education of Minzdrav of Russia, Moscow
Published: September 2023

Cardiovascular diseases (hereinafter - CVD) have become the leading cause of death worldwide: for no other reason as many people die every year as from CVD. This problem affects low and middle income countries to varying degrees. More than 80% of deaths from CVD occur in these countries, almost equally among men and women, however, patients who survived after myocardial infarction (hereinafter - MI) are at high risk of death. According to the main facts of the WHO, 17.9 million people died from CVD in 2016, which accounted for 31% of all deaths in the world. In this connection, it is necessary to improve medical rehabilitation (hereinafter - MR), in particular for CVD, especially on an outpatient basis. Competent MR, cardiac rehabilitation in patients with myocardial infarction is associated with improved survival and effectiveness of quality of life, as well as prevention of recurrent MI. There is a legislative framework FZ-No. 323 of 21.11.2011 "On the basics of health protection of citizens in the Russian Federation" concerning medical rehabilitation and "Procedure for organizing medical rehabilitation" No. 1705n of 29.12.2012. Multiple meta-analysis showed that cardiovascular rehabilitation (hereinafter - CVR) reduces mortality in patients with coronary artery disease. Despite the recommendations and recommending the use of programs for patients with previous MI, patient participation in these programs remains low, which has led to the development of alternative models of medical rehabilitation.
An Obstructive Sleep Apnea - A Novel Public Health Threat
Authors: Gresova S , Gaborova M , Stimmelova J , Peregrim I , Svorc P , Donic V , Pallayova M
Published: September 2023

In patients with obstructive sleep apnea (OSA) during obstructive events, episodes of hypoxia and hypercapnia may modulate the autonomic nervous system (ANS) by increasing sympathetic tone and irritability, which contributes to sympathovagal imbalance and ultimately dysautonomia. Because OSA can alter ANS function through biochemical changes, we can assume that heart rate variability (HRV) will be altered in patients with OSA. Most studies show that in both the time and frequency domains, patients with OSA have higher sympathetic components and lower parasympathetic dominance than healthy controls. These results confirm autonomic dysfunction in these patients, but also provide new therapeutic directions. Respiratory methods that modulate ANS, e.g., cardiorespiratory biofeedback, could be beneficial for these patients. Heart rate variability assessment can be used as a tool to evaluate the effectiveness of OSA treatment due to its association with autonomic impairment.
The Status of Nurses's Oral Care Practices and Dental Hygienist’s Medical Cooperation Needs for Inpatients
Authors:   The Korean Society of Oral Health Science, Lee Tae-Rim , Lim Na-Yeon , Kwon Su-Hee , Cha Eun-Suk , Choi Seo-Jeong , Jeong Geum-Bi , Kwak Eun-Bi
Published: September 2023

Objectives: The aim of this study is to serve as basic data to prove the need for dental hygienists through the cooperation of dental hygienists, who are oral care experts.
Methods: A survey was conducted on nurses who perform nursing work in general hospitals and university hospital wards located in Busan, and Ulsan.
Results: As a result of the oral nursing performance of the subjects with educational experience was higher on average than the subjects without educational experience, which was statistically significant(p<0.05).
Conclusions: It was found that educational experience had an effect on performing oral care. In order to improve the quality of oral care the participation of dental hygienists specializing in oral care is required, and it is thought that systematic education on oral care of nursing personnel is necessary.
Effects of Combined Administration of Sulforaphane and Resveratrol on Orofacial Pain Control in Rats
Authors:   The Korean Society of Oral Health Science, Park Min-kyoung , Cheon Sae-hee , Kim Kyung-min , Kim Hye-jin , Lee Min-kyung
Published: September 2023

Objectives: This study was designed to confirm the effects of natural products on the control of facial pain.
Methods: In this study, 5% formalin was injected into the face of the experimental animals to induce pain behavioral responses, and sulforaphane 15 μg or 150 μg/50 μl and resveratrol 20 μg or 200 μg/50 μl were pre-treated to confirm the pain control effects.
Results: The two drugs showed pain-modifying effects in a concentration-dependent manner. In addition, a significant analgesic effect was confirmed when the two drugs were co-administered at low concentrations.
Conclusions: Therefore, through this experiment, sulforaphane and resveratrol can be effective therapeutic agents for controlling orofacial pain.
Differences between Subjective Effects and Oral Conditions of Subjects According to Brushing Methods
Authors:   The Korean Society of Oral Health Science, Kim Hye-Jin , Kim Kyung-Min
Published: September 2023

Objectives: This Study was conducted to find out the effects on the oral cavity and the subjective effects of subjects between brushing methods based on the Bass’ method.
Methods: From May 4 to May 11, 2023, Group2 was trained on rotational and random methods based on the Bass’ method, and an evaluation was conducted one week later.
Results: BOP, O’Leary index, and BB check levels were reduced for both Bass’+Rolling method and Bass’+Random method.
Conclusions: The Rolling method may not necessarily be an advantageous method of brushing teeth, and repeated brushing education and efforts by dental hygienists for follow-up care are required to change tooth brushing.
Relevance of Dental Hygienists Knowledge of Systemic Diseases, Awareness of Emergency Response, and Educational Needs in Busan and Gyeongnam Gegions
Authors:   The Korean Society of Oral Health Science, Kim So-Young , Kim Hye-Jin , Lee Min-Kyung , Yoon Hyun-Seo
Published: September 2023

Objectives: It is intended to be used as a basis for the development of educational materials to improve the dental care of patients with systemic diseases and to reduce the psychological burden on dental hygienists involved in the care.
Methods: A self-administered survey was conducted among 311 dental hygienists in Busan and Gyeongnam, and statistical analysis was performed using SPSS 26.0.
Results: systemic disease training experience, knowledge level, and training content needs were positively correlated.
Conclusions: Educational programs should be developed and ongoing training should be provided to close the gap in systemic disease knowledge.
A Study on the Literature for Effective Use of Interdental brush
Authors:   The Korean Society of Oral Health Science, Kim Hye-Jin , Kim Kyung-Min , Yu Jin-Sil
Published: September 2023

Objectives: Measures for the efficient use of interdental brush were reviewed.
Methods: From June 1 to October 30, 2022, the significance and utilization of interdental brushes were studied, and data collection was mainly conducted using literature surveys and Internet searches.
Results: After checking the size of the interdental brush in the mouth, education on the insertion path and use of the interdental brush should be followed. Depending on the periodontal health condition, the time of intervention of the interdental brush may vary.
Conclusions: For efficient use of interdental brushes, it is essential to check the size of interdental brushes in the mouth, and training on the insertion path and use of interdental brushes should be followed.
The Effect of Smartphone Addiction and Stress on Self-Esteem in College Students
Authors:   The Korean Society of Oral Health Science, Kang Hyun-Joo
Published: September 2023

Objectives: This study is to investigate the factors that the Effect of Smartphone Addiction, Stress, Self-Esteem among Students Majoring in College Students.
Methods: This study were convenience sampling of 238 students in College Students departments at Jeollado and Gwangju Metropolitan City area. The data collection was confirmed by frequency, average and standard deviation, Pearson's Correction coefficient, and multiple regression analysis with the SPSS 21.0 program.
Results: Factors affecting Self-Esteem were Smartphone Addiction(β=-.319, p<.000) and academic performance(β=.195, p<.000) and Smartphone usage time(β =-.223, p<.000).
Conclusions: In order to increase the Self-Esteem of students, it is necessary to provide health education to Smartphone Addiction and to provide health training programs to strengthen Self-Esteem.
Governance Evaluation and Implications of the Family Dentist System for the Students: Focusing on the Case of the Seoul Metropolitan Government
Authors:   The Korean Society of Oral Health Science, Shon Changwoo , Kim Jungah , Yi Seonju
Published: September 2023

Objectives: The study was to assess the level of governance perceived by key stakeholders regarding the family dentist system for students in Seoul.
Methods: The evaluation tool used for this assessment was a health policy governance evaluation tool developed by the World Bank.
Results: The study revealed that the dimension of 'transparency and information' of the family dentist system for students in Seoul received the highest level of governance. The dimensions of 'consistency and stability' and 'coherent decision-making structure' also received a good level of governance. However, there were areas where governance was found to be insufficient, specifically in terms of 'stakeholder participation' and 'supervision and regulation'.
Conclusions: To implement the family dentist system for students nationwide, enhancing the governance framework is crucial, allowing key stakeholders such as oral health professionals, students, and their parents to engage.
Analysis of Maximum Occlusal Force according to General and Masticatory Characteristics in Some Adults
Authors:   The Korean Society of Oral Health Science, Yun Jung-Won , Park Jeong-Hui , Lee Ha-Won , Kim Sue-Ryun , Yu Su-Bin
Published: September 2023

Objectives: The purpose of this study is to confirm the relationship of maximum occlusal force and physical and oral features.
Methods: A self-reported questionnaire was filled by 50 adults and oral examination was conducted by dental hygienist in Gyeongnam from March to June, 2023. The occlusal force was measured by Innobyte for 2 times. All presented results were analysed by SPSS ver 21.0.
Results: The maximum occlusal force of males is higher than females(p<0.05). Those who had no bruxism, subjective malocclusion showed the greater occlusal force than candidates with bruxism, subjective malocclusion(p<0.05).
Conclusions: The gender, bruxism and subjective malocclusion are associated with the occlusal force.