bluuebunny/crossref_metadata_2025 huggingface dataset:
Влияние физической культуры и спорта на здоровье студентов в вузе и их вовлеченность к здоровому образу жизни вне учебных занятий
Authors: Ибрагимов И.Ф. , Курмаев З.Ф. , Галиахметова А.Р.
Published: February 2024

В данной статье исследуется влияние физической активности на здоровье студентов и их вовлеченность в активный образ жизни вне занятий. Основная цель исследования заключается в изучении этого воздействия, а также выявлении факторов, влияющих на уровень физической активности среди студентов. В работе используются методы теоретического обзора литературных источников и анализа проведенных опросов. Результаты опроса студентов первых и вторых курсов показывают положительное отношение к физической активности и предлагают эффективные подходы для привлечения студентов к активному образу жизни. Выводы статьи подчеркивают, что занятия физической культурой и спортом оказывают положительное воздействие на здоровье студенческой молодежи, способствуя укреплению физического состояния, снижению уровня стресса и улучшению настроения.
The Influence of Physical Exercises on the Flexibility of Older Individuals with Knee Osteoarthritis: A Systematic Review
Authors: Gomes Santos Aline Cristina , Silva Caiado Vanessa Da , Moreira-Marconi Eloá , Teixeira-Silva Ygor , Gonçalves De Meirelles Alexandre , Seixas Adérito , Rodrigues Lacerda Ana Cristina , Sonza Anelise , Mendonça Vanessa Amaral , Bernardo-Filho Mario , Cunha De Sá-Caputo Danúbia Da
Published: February 2024

Background: Flexibility is a component of functional capacity and is relevant in maintaining the musculature and structures adjacent to the joints. Then, the improvement of the flexibility must be a critical goal in the rehabilitation programs. By improving flexibility in knee osteoarthritis (KOA) individuals, the pain is relieved, the risk of injury is reduced, and the need for surgical interventions is delayed. We aimed to summarize the available literature on the influence of different physical exercise modalities on flexibility in older KOA individuals.
Methods: This study followed the PRISMA statement and registered in PROSPERO (CRD42020195786). Seven databases (MEDLINE/PubMed; PEDro; CINAHL; Scopus; Web of Science; Embase; and SPORTDiscus) were screened for papers published prior to Sep 6, 2022. The PEDro scale, Cochrane collaborations, and ROBINS-I tools were used to evaluate the methodological quality and risk of bias.
Results: Ten studies (including 438 participants diagnosed with KOA) fulfilled the eligibility criteria, and nine concluded that flexibility was improved after a physical exercise program.
Conclusion: Despite the modality, physical exercise improves flexibility in older KOA individuals, improving the functional capacity. Health professionals engaged in KOA rehabilitation should use physical exercise as a strategy to improve the flexibility of this population.
Severe Pain and Postoperative Effects during Hysterosal-pingography: A Meta-Analysis
Authors: Jiang ShengPan , Gao Shan , Tan YiQing , Yang Qian , Zhou Tao , Zheng ShiLin , Lei WenFeng , Wang FuHua , Liu Xuan
Published: February 2024

Background: We aimed to evaluate the impact of pain on patients during Hysterosalpingography (HSG).
Methods: PubMed, PMC and other journals were searched for randomized controlled trials (RCTS) on HSG. Appropriate articles were selected for inclusion and reasonable exclusion according to keywords. Following a thorough review of the relevant literature, the process of literature screening was conducted in accordance with the aforementioned criteria. The methodological quality of the studies was assessed using the risk of bias assessment tool developed by the Cochrane Collaboration. Meta-analysis was conducted using RevMan 5.4.1 software.
Results: Twelve studies were included, including 1530 cases in the experimental group and 1545 cases in the control group. The literature summarizes the basic information of patients during HSG and makes statistics on the differences in visual analog scale (VAS) and pain perception. The findings from the HSG examination revealed a lack of significant association between patients' pain sensation and their age and BMI. However, the duration of pregnancy in patients decreased following HSG treatment (95%CI (-18.84 to -3.58), P=0.004).Compared with conventional testing, HSG could effectively reduce the pregnancy time of patients (95%CI (-18.84, -3.58), P=0.004), reduce the VAS of patients (95%CI (-4.73, -1.51), P=0.0001), and increase the number of patients without pain (95%CI (1.80, 10.43), P=0.001).
Conclusion: During the HSG examination, acceptable pain avoidance is generated and can be relieved over time. At present, there is no effective alternative method, so the patient should cooperate with the doctor to complete the examination, to relieve the pain.
The Role of Water, Sanitation and Hygiene (WaSH) Interventions on Health and Behavioral Outcomes during Humanitarian Crisis: A Systematic Review and Meta-Analysis
Authors: Alareqi Mohammed Muneer , Alshoaibi Lina Hassan , Liu Yanli , Dhital Sushma , Zhang Benzhong
Published: February 2024

Background: In humanitarian crises, water, sanitation and hygiene interventions are critical for the survival of people. However, strong evidence-based information is still limited. In order to describe the quantity and quality of current evidence, we conducted an evidence gap map provides a visual overview, highlighting areas lacking evidence.
Methods: According to developed inclusion and exclusion criteria, a systematic literature search was conducted to find related systematic reviews and meta-analyses. The databases, including PubMed, Web of Science, SCOPUS and Cochrane were searched using search strings from 2000 until 2021. Characteristics of the included reviews were extracted and summarized. Two persons evaluated methodological quality independently using the AMSTAR tool. Invite a third person to solve any discrepancies.
Results: This study revealed seven systematic reviews, including one meta-analysis. One study was of high quality, four of medium, and two of low quality. A total of 272 primary studies were included with a median value of 38.8 (range, 6-106) which deeply analyzed for data extraction. Cross-sectional, case-control, and qualitative case studies were the most used study designs. Diarrheal diseases were the most reported outcomes representing 46% of the impact evaluations. Cholera outbreaks account for 43% of a crisis context. The research gaps were insufficient reporting of some interventions with related outcomes and the geographical distribution of current evidence.
Conclusion: There is a limitation in current evidence represented by a lack of high-quality and experimental studies investigate the impact of water, sanitation and hygiene (WaSH) interventions on health and behavioral outcomes in humanitarian sittings.
Proteomics Clustering Research of ITRAQ Markers in Plasma of AIDS Patients with Different Chinese Medicine Syndromes
Authors: Zhang Haiyan , Qiu Quan , Li Qingya , Feng Long , Li Dongyang , Zhang Miao , Wang Juan , Ma Suna , Xu Liran
Published: February 2024

Background: We aimed to distinguish the different Chinese medicine (CM) syndromes of acquired immune deficiency syndrome (AIDS) patients at the proteomics level.
Methods: We collected AIDS patients diagnosed with different CM syndromes from Weishi County, Kaifeng City, Henan Province, China, including Qi-deficiency syndrome (named QD group) and dampness-heat syndrome (named DH group). Healthy people were collected as controls from Weishi County, Kaifeng city, Henan Province, China. The plasma from three groups were labeled with ITRAQ, LC/MC was used for protein quantitative analysis. Finally, sequence search and cluster analysis were performed.
Results: Overall, 27 different proteins were found. Three proteins were up-regulated and 2 proteins down-regulated in the QD group, 11 proteins up-regulated and 13 proteins down-regulated in the DH group. Compared with DH group, there were 7 different proteins in QD group, among which 5 proteins were down-regulated and 2 proteins were up-regulated. When the target protein of DH group was up-regulated, the protein of HC group was down-regulated correspondingly.
Conclusion: The significance analysis and clustering of protein results showed that DH group was significantly different from QD group and HC group at the protein level (P<0.05). However, the QD group could not be effectively distinguished from the HC group. AAT, PF4, C-reactive protein and c4bp may be used as potential biomarkers in DH group. Mass spectrometry based on feature selection can be used to classify different CM syndromes.
Sociodemographic Factors Associated with Breast Cancer Screening Among Women in Serbia, National Health Survey
Authors: Djordjević Slavica , Dimitrijev Igor , Boričić Katarina , Radovanović Snezana , Vukomanović Ivana Simić , Mihaljević Olgica , Jovanović Sofija , Randjelović Nevena , Lacković Ana , Knezević Snezana , Stanković Veroslava , Sorak Marija , Jovanović Verica
Published: February 2024

Background: Approximately 2.3 million female breast cancer cases were identified globally in 2020, resulting in 685,000 fatalities among women. Serbia too experiences a high breast cancer burden. Effective reduction of breast cancer incidence and mortality necessitates strategic measures encompassing the implementation of cost-effective screening technology. However, various impediments to screening implementation persist. We aimed to estimate the impact of socioeconomic factors on breast cancer screening in Serbia.
Methods: Data from the 2019 National Health Survey of the population of Serbia was. The research was a descriptive, cross-sectional analytical study by design, on a representative sample of the population of Serbia. Data from women aged 15+ yr were used to examine the demographic and socioeconomic factors associated with breast cancer screening inequalities.
Results: In Serbia the age group of women who predominantly participated in organized breast cancer screening (39.5%) were the ones aged 65+ yr. Women with a secondary education were 2.1x more likely to undergo a screening exam voluntarily (57.5%), compared to women with a higher education background (26.6%). When considering marital and financial circumstances, married/unmarried women from an affluent financial category exhibited a notably higher frequency of self-initiating a mammography (73% and 48.5%) in comparison to those financially struggling (27.6%).
Conclusion:  Strong support is imperative for countries to establish prevention and early detection programs for cancer.
Quality of Life of Patients with Oral Squamous Cell Carcinoma
Authors: Markovic Maja Milosevic , Petrovic Milan , Latas Milan , Djordjevic Igor , Milovanovic Srdjan , Jovanovic Svetlana
Published: February 2024

Background: Oral squamous cell carcinoma (OSCC) has numerous physical, psychosocial and financial implications, which significantly affect patients' quality of life. We aimed to determine the health-related quality of life (HRQoL) and identify quality of life (QoL) predictors in patients with OSCC.
Methods: We included 64 consecutive patients aged 40 to 80 yr treated for OSCC from Jan to Dec 2021. Health-related QoL was evaluated using the 30-item Cancer Quality of Life Questionnaire (QLQ-C30) and the 35-item Head and Neck Cancer-Quality of Life Questionnaire (QLQ-H&N35). The demographic questionnaire and clinical parameters were also presented.
Results: The functioning scale in the QLQ-C30 questionnaire with the lowest average score was Global health status. The mean QLQ-C30 summary score (80.92 ± 10.4) was higher than the Global health status score (50.5 ± 22.2). In the QLQ-H&N35 questionnaire, the symptoms with highest scores were weight loss, dry mouth, and social eating. Linear regression analysis demonstrated that Global health status score was associated with education level [β-coefficient = 19.33 (95% CI: 10.7-24.9, P=0.004], alcohol consumption [β-coefficient=10.04 (95% CI: 4.5-14.8), P=0.023] and invasive surgical procedure [β-coefficient=22.75 (95% CI: 15.0-30.5), P=0.002]. The QLQ-C30 summary score was associated with living alone [β-coefficient= -20.05 (95% CI: −29.91-(−10.21), P=0.018], smoking status [β-coefficient=4.35 (95% CI: 1.8-6.91), P=0.043] and alcohol consumption [β-coefficient =4.59 (95% CI: 1.99-7.19), P=0.037].
Conclusion: We found several significant predictors of worse perception of HRQoL among patients with OSCC, which may be useful for specific prevention and treatment in order to achieve better QoL.
Trend of Cardiovascular Diseases in the Northern Regions of the Republic of Kazakhstan at the Outpatient Level
Authors: Berdeshova Gulshara , Musina Aiman , Orakbay Lyazat , Tolegenova Aidana , Zhorabek Saya , Amanova Assel , Kulbayeva Shynar
Published: February 2024

Background: We aimed to study the rate and trends of the incidence of chronic cardiovascular diseases in urban and rural areas of the northern regions of the Republic of Kazakhstan (RK) from 2015 to 2020.
Methods: The retrospective data were analyzed using modern methods of biomedical statistics. We used the Electronic Register of Dispensary Patients (2015-2020), where we conducted a retrospective study and trend calculations. The study included patients with chronic cardiovascular diseases (CVD) (according to the International Classifier of Diseases-10, the following nosologies were identified: I25 chronic coronary heart disease and its nosological forms (I25.0-I25.9), and patients by age categories, consisting of dispensary registration in polyclinics of the northern region of the RK.
Results: For 2015 - 2020 in the northern region (urban and rural) of RK, 12,315 patients were registered, who were on dispensary records for the chronic CVD. This amounted to 87.3% of urban residents, and 12.7% of rural residents. The share of patients with chronic CVD in the northern region of the republic by age groups had a bimodal growth pattern with the first peak at the age of 60-74 (40.4%) and the second - at the age of 45-59 (37.7%).
Conclusion: This study notes an increase in chronic CVD, both in urban and rural areas of the northern region of the RK. This once again proves the need for the development, implementation and use of modern tools in the provision of medical services to cardiological patients at the outpatient level, taking into account the characteristics of the northern regions of our country.
How Age, Sex and Transfusion Affects the Incidence of Endo-crine and Bone Density Disorders in Major Thalassemic Patients
Authors: Mohajeri-Tehrani Mohammad-Reza , Alemzadeh Seyyed Amirsina , Marzbali Fatemeh Abbaszadeh , Nasserisina Sadaf , Hosnan Fatemeh , Naghghash Ameneh , Hamidieh Amir Ali , Behfar Maryam , Mohseni Fariba , Rashidian Hoda , Shirazi Sara , Aboee-Rad Maryam , Qorbani Mostafa , Larijani Bagher , Hamidi Zohreh
Published: February 2024

Background: Beta-thalassemia major patients frequently have endocrinopathies. We tried to determine relation between demographic and transfusion factor and endocrinopathies.
Methods: Major beta-thalassemia patients (n=114 cases), 3–38 yr of age, entered this study. Female to male ratio was 51/63. Children (less than 20 yr) formed 57% of participants. Information about bone mineral density (BMD) and hormonal and biochemistry blood evaluation including fasting blood sugar (FBS), ferritin, triiodothyronine (T3), thyroxine (T4) and thyroid-stimulating hormone (TSH), luteinizing hormone (LH) and follicle-stimulating hormone (FSH), testosterone (males), and estradiol (females) entered data sheet.
Results: Sex and ferritin level showed no significant correlation with above disorders. Age significantly correlated to short stature, diabetes, low BMD at femur and neck (P, 0.031, 0.008, 0.009 and <0.001, respectively). The risk of short stature had increased in 12 yr and older patients 7.71 times than younger patients (P= 0.008). The risk of diabetes had increased in 35 yr and older patients 26.25 times than younger patients (P= 0.03).  The risk of Z-score ≤ -2 in femoral region has increased in 19 yr and older patients 5.84 times than younger patients (P= 0.002). The risk of Z-score ≤ -2 in spinal region has increased in 14 yr and older patients 17 times than younger patients (P= 0.007).
Conclusion: The main factor related with endocrinopathies was age. The correlation between age and short stature, diabetes and low BMD was positive. Therefore, we recommend early monitoring of thalassemia patients (in their late childhood and early teenage) for these complications.
Using Modern Learning Method to Teach Pharmacy Students Psychopharmacotherapy
Authors: Zarif-Yeganeh Morvarid , Mafinejad Mahboobeh Khabaz , Mohebbi Niayesh , Kiani Muhammad , Rezaei Eisa , Ebrahimpour Sholeh , Namazi Soha
Published: February 2024

Background: Applying modern educational methods for digital native students seems necessary. Active learning strategies promote students’ skills and knowledge. This study was conducted to design and evaluate active learning methods by teaching psychopharmacotherapy to pharmacy students.
Methods: This was a quasi-experimental study with three randomized study groups (control, game, and multimedia), using a pre-and post-test design, conducted on 155 students of 5-year pharmacy in 2022 at the Faculty of Pharmacy of Tehran University of Medical Sciences, Iran. Overall, 18 clinical cases were designed for the basic structure of interventions. After teaching psychopharmacotherapy contents through lecturing, the pre-test was held. The next steps were playing the educational game, studying the multimedia case-based learning files, and then completing questionnaires, respectively. Then, a post-test was held.
Results: 65.33% of participants were female and 34.66% were male. The pre-test and post-test scores comparison showed no difference in control group (P=0.409). However, in the serious game and multimedia groups, the average score of pre-test and post-test had a statistically significant difference (P<0.001, P=0.002 respectively), this difference was higher in the serious game group. Questionnaire evaluation showed substantial differences between game and multimedia groups.
Conclusion: The educational interventions were able to improve student's knowledge and skills so they can better help patients and promote public health. In the sections of Confidence, Social Interactions, Fun, Focused attention, Learnability, Relevance, and Perceived Learning, the serious game far outweighed the multimedia case-based learning.
Whole Exome Sequencing of Non-Syndromic Hearing Loss Patients
Authors: Naddafnia Hossein , Noormohammadi Zahra , Irani Shiva , Salahshoorifar Iman
Published: February 2024

Background: Hearing loss is the second most common disease after mental retardation in Iran. Autosomal recessive non-syndromic hearing loss (ARNSHL) is an extreme and highly heterogeneous disease, for which more than 70 genes have been identified. Considering the frequency of family marriage as well as the importance of ARNSHL in Iran, we evaluated the genetic factors involved in this type of deafness.
Methods: We performed the whole exome sequencing (WES) of eight Iranian subjects with severe non-syndromic hearing loss selected from 110 well-characterized subjects with non-syndromic hearing loss from 2017-2019. The patients with mutated GJB2 and GJB6 genes were excluded from the study.
Results: The use of the whole exome sequencing method revealed 10 different mutations in 7 genes, including SLC26A4 (c.1234G>T), FGF3 (c.45DelC, c.466T>C), ADGRV1 (c.12528-2A>C, c.16226-16227insAGTC), OTOG (c.7454delG), OTOF (c.3570+2T>C), ESPN (c.992G>A), OTOA (c.2359G>T, c.2353A>C). Seven new variants were observed in seven families including SLC26A4 (c.1234G>T), FGF3 (c.45DelC), ADGRV1 (c.12528-2A>C), OTOG (c.7454delG), ADGRV1 (c.16226-16227insAGTC), OTOF (c.3570+2T>C).
Conclusion: The causal mutation of ARNSHL was found in all patients using the WES. Meta-analysis studies can help to identify common mutations causing deafness in any population to facilitate identification of carriers and subjects with deafness.
The Trend of Death Rate and Causes of Death Based on the ICD-10 among Young People in Iran within the Last Three Decades
Authors: Heydari Mahdiyeh , Yarifard Khadijeh , Tajvar Maryam
Published: February 2024

Background: Youth is undeniably the most important resource of any country. This study aimed to determine the trend of mortality rate and the cause of death, based on the ICD-10, among young people in Iran and examines significance of the changes in any cause during the last three decades.
Methods: The present study is a secondary analysis of data, which examines the trend of death rate and its causes among young adult, aged 15-24 yr, longitudinally during 1990-2019. The data source was the GBD website. Linear Regression analysis was used to measure the slope of changes in mortality rates and causes of death during the period, where "time" was the independent variable and "mortality rate" and "causes of mortality" were dependent variables.
Results: The death rate of young people declined by 56% during the period, equal to an average of 2.17 units per year. The most common cause of death has been injuries (69%), then NCDs (25%), and finally communicable diseases (6%). However, death due to injuries (except SUD), communicable diseases (except HIV), and NCDs (except musculoskeletal disorders) declined significantly by 1.43, 0.3, and 0.09 units per year, over 30 yr respectively.
Conclusion: Examining past trends in death rates and causes strengthens insights into the state and future trends in health and death-related indicators, which are crucial for policy-making, especially in developing countries with limited resources.
The effectiveness of family caregivers as case managers for patients with severe mental illness
Authors: Rahmani Farnaz , Asghari Elnaz
Published: February 2024

The Article Abstract is not available.
Applying Carspecken’s critical ethnography method to uncover the culture of health disparity in intensive care units
Authors: Yarahmadi Sajad , Soleimani Mohsen , Gholami Mohammad , Fakhr-Movahedi Ali , Saeidi Madani Seyed Mohsen
Published: February 2024

Background & Aim: Carspecken’s critical ethnography method has gained prominence in nursing research, necessitating a fresh perspective on its practicality and advantages. This study aims to provide a unique viewpoint on using critical ethnography as a foundational methodology to uncover health disparity culture in intensive care units.
Methods & Materials: While emphasizing its review design with original examples, this perspective piece provides a practical explanation of Carspecken’s five-stage critical ethnography approach. Grounded in the ontological and epistemological paradigm, this essay examines critical ethnography as a crucial approach to illuminating the discursive culture surrounding health disparities. Also, this study presents original instances of monological and dialogical data, reconstructive analysis, and findings from a study that was carried out to provide more perspective on implementation. It also mentions how it relates the findings to social factors and sociopolitical theories.
Results: The study reveals nuanced insights into the practicality and advantages of Carspecken’s method, shedding light on social processes contributing to health disparities in intensive care units. This method allowed us to identify how external powers extend to the intensive care unit, revealing a concealed culture that disrupts service provision balance. It exposed individual, organizational, and systemic roots contributing to disparities. Additionally, it highlighted how individual diversities can lead to disparity.
Conclusion: This study highlights the significance of Carspecken’s critical ethnography in nursing studies within the critical theory tradition. It is argued that Carspecken’s approach to critical ethnography is particularly instrumental in elucidating the social structures contributing to health disparities.
Statistical concerns, invalid construct validity, and future recommendations
Authors: Sharif-Nia Hamid , She Long , Osborne Jason , Gorgulu Ozkan , Khoshnavay Fomani Fatemeh , Goudarzian Amir Hossein
Published: February 2024

The Article Abstract is not available.
Prevalence of geriatric syndromes and associated factors in Iranian older adults with type 2 diabetes: A population-based correlational study
Authors: Rahimi Mehdi , Poortaghi Sarieh , Negarandeh Reza
Published: February 2024

Background & Aim: Geriatric syndromes are known as a major obstacle in the treatment and care of older adults with diabetes. This study aimed to determine the prevalence of geriatric syndromes and associated factors in community-dwelling older adults with diabetes in the south of Tehran, Iran, in 2022.
Methods & Materials: A population-based correlational study was conducted among 392 older adults with diabetes, covered by selected health centers in the south of Tehran, Iran, using the multistage sampling method. Persian forms of geriatric assessment tools were used, including Mini-Mental State Examination, Activities of Daily Living, Instrumental Activities of Daily Living, Mini Nutritional Assessment, and Geriatric Depression Scale. The obtained data were analyzed by descriptive and chi-square test in SPSS-26.
Results: The mean age of the participants was 69.5±6 years (63% female, 37% male). About 54.6% of the older adults with diabetes studied had three or more Geriatric syndromes. Polypharmacy was the most prevalent geriatric syndrome (76.5%). The number of geriatric syndromes had a significant association with female gender (p<0.001), lower education (p<0.001), loss of the spouse (p= 0.004), and lower-income (p=0.019). Also, with the increase in the number of diabetes comorbidities, the occurrence of all geriatric syndromes increased significantly (p<0.001).
Conclusion: The prevalence of geriatric syndromes in older adults with diabetes in the south of Tehran is very high and warning. Due to the increasing population of older adults in Iran, policymakers and healthcare providers should take appropriate actions to confront the issue with a comprehensive understanding of the present condition.
Examining the relationship between pediatric nurses’ liking of children levels and their codependency
Authors: Pekyiğit Aylin , Yıldırım Tuğba , Bağrıyanık Burcu Çalık
Published: February 2024

Background & Aim: Codependency is a type of pathological relationship.  Pediatric nurses' liking of children may make them accept children more easily, but it may also lead to codependency. This study aims to examine the relationship between pediatric nurses’ liking of children's levels and their codependency.
Methods & Materials: This study is a descriptive correlational study. Data were collected online via Google Forms by exponential non-discriminative snowball sampling using the Demographic Form, the Barnett Liking of Children Scale, and the Nurse Codependency Questionnaire. The study was completed with 260 nurses. The Mann-Whitney U test, Kruskal-Wallis H test, and Spearman correlation were used to analyze the data.
Results: In this study, the nurses' BLCS median score was 86 (78-93) and their Nurse Codependency Questionnaire median score was 72 (64-82). A significant but weak correlation was observed both between age and the BLCS score (r=0.132; p<0.05) and between the overall Barnett Liking of Children Scale and Nurse Codependency Questionnaire scores (r= 0.182; p<0.05).
Conclusion: In this study, it was determined that as nurses' level of liking children increased, their level of codependency decreased. The findings suggest a significant, albeit weak, correlation between these two variables. These results underscore the importance of further research to fully understand the implications of these relationships and their potential impact on the nursing profession.
Investigating the level of medication adherence and subjective recovery in patients diagnosed with schizophrenia
Authors: Öz Yüksel Can , Duran Songül
Published: February 2024

Background & Aim: Low compliance with medication in patients with schizophrenia may negatively affect the quality of life and subjective recovery. The objective was to analyze the association between medical adherence and subjective recovery in individuals diagnosed with schizophrenia.
Methods & Materials: This descriptive and correlational research was conducted between July and August 2023. 120 patients registered with a Schizophrenia Relatives Association in Türkiye were included in the study using simple random sampling. Demographic questionnaire, Medication Adherence Report Scale, and Subjective Recovery Assessment Scale were used in the study. Percentage, mean, t-test in independent groups, one-way ANOVA, and Pearson correlation coefficient were used to data analysis in SPSS 25.
Results: Medication Adherence and Subjective Recovery mean scores were 22.85±3.57 and 61.82±15.37 respectively. It was revealed that there is a positive and statistically significant relationship between Medication Adherence and Subjective Recovery scores (r=0.269, p<0.01). As well as between age and Medication Adherence Report Scale (r=0.215, p<0.05). The subjective recovery level was significantly lower in smokers compared to non-smokers (p<0.05).
Conclusion: Subjective recovery levels of psychiatric patients can be increased by monitoring their medication adherence levels. Supportive interventions (giving motivational talks for medication use, following up with patients by phone or home visit, etc.) should be implemented for those who do not adhere to their medication regimen.
Effect of 3-Amino-1,2,4-Triazole-5-Carboxylic Acid on Human Blood Erythrocyte Catalase
Authors: Çıkrıkcı Kübra , Gencer Nahit
Published: February 2024

Catalase is an antioxidant enzyme with great therapeutic potential that scavenges hydrogen peroxide, a reactive oxygen species produced during cellular metabolism. Substances containing 1,2,4-triazole structures are biologically important heterocyclic compounds found in the structure of many pharmaceutical drugs used in drug discovery studies against various types of diseases in the human body. In this study, the effect of phosphate buffer prepared at different pHs and 3-amino-1,2,4-triazole-5-carboxylic acid (ATZc) on catalase enzyme activity in human blood erythrocytes was determined. It was determined that the catalase enzyme was inhibited by ATZc at different pH levels. The weakest inhibition was observed at pH 5.5 (IC50:49.01 µM), whereas the strongest inhibition was observed at pH 7.5 (IC50:23.21 µM).
INDICATIVOS DA NECROPOLÍTICA SOCIOAMBIENTAL BRASILEIRA
Authors: De Souza-Lima José Edmilson , Ricci Salomoni Luciana , Gewehr de Oliveira Fernanda
Published: February 2024

No contexto de crise socioambiental que se evidencia na Amazônia Legal, este artigo tem como objetivo geral identificar vínculos entre as ações do governo brasileiro vigente (2019-2022) e a necropolítica socioambiental. Dentre os objetivos específicos, a investigação proposta visa a demonstrar a participação do governo federal em vigor no aumento dos incêndios, desmatamentos, invasões a territórios indígenas, garimpo ilegal e violência na Amazônia Legal. Com base na obra de Achille Mbembe, este estudo busca delimitar uma crise humanitária originada na necropolítica do governo Bolsonaro. Fazendo uso de uma metodologia quantitativa, esta pesquisa partiu da coleta de dados relacionados à desarticulação de normas ambientais garantidoras de políticas públicas, discursos oficiais de incitação à violação de normas ambientais e inércia no combate a crimes ambientais na Amazônia e contra os povos indígenas no período de janeiro de 2019 a agosto de 2022. Em uma análise qualitativa, tais dados foram inseridos em um quadro analítico derivado da obra de Mbembe sobre a necropolítica. Como resultado, restam reforçadas e justificadas as denúncias de crime contra a humanidade que tramitam contra o Presidente da República perante o Tribunal Penal Internacional (TPI).
O PROCESSO LEGISLATIVO REVISIONAL NA POLÍTICA URBANA E SEUS FUNDAMENTOS: DEMOCRACIA E SUSTENTABILIDADE
Authors: Santos Samuel
Published: February 2024

Este artigo tem como tema a legislação urbanística, com análise da determinação exposta no Estatuto da Cidade (Lei n. 10.257/2001, art. 40, § 3º) que trata da revisão periódica do Plano Diretor a cada dez anos. O problema do artigo é resumido da seguinte forma: O que é e quais são as relações entre o processo legislativo revisional e as diretrizes da política urbana de gestão democrática e do direito a cidades sustentáveis? E quais são suas possibilidades e limites para a política urbana? Os objetivos da pesquisa são relacionar tal característica com elementos específicos da dogmática jurídica urbanística e indicar a existência de um direito difuso ao processo legislativo revisional como instrumento de aprimoramento da política urbana, do que resulta a pertinência do reconhecimento do princípio do revisionismo legislativo. A pesquisa foi desenvolvida com a aplicação do método dedutivo e da técnica bibliográfica, relacionando as características do processo legislativo revisional com as teorias democráticas e o Direito Ambiental. Como resultado, verificou-se que o reconhecimento de tal vínculo apresenta-se fundamental para a compreensão das relações da legislação urbanística com a dinâmica temporal dos espaços urbanos, o respeito à deliberação democrática e ao planejamento sustentável.
An insight into the molecules and materials of the haustorium of the Asian Palmyra Palm (Borassus flabellifer) and their nutraceutical values
Authors: Kuldeep Sweety Angela , Vijayakumar Vidhyashini , Segaruban Showmiya , Sinnathurai Yunitha , Hossain Mohammed Saium , Begum Kohinoor , Paul Jefwin , Selvakumar Paulraj Mosae
Published: February 2024

The B. flabellifer L. has untapped potential in sustainable development and its products have many high food and medicinal values. Palmyraculture is defined as the plantation and utilization of Palmyra palm for self-reliance and sustainable development. The endosperm/embryo of germinated seeds is an important biomaterial, also known as haustorium. This paper provides comprehensive insights into the molecules of the haustorium, especially those of pharmaceutical and nutritional interests, and briefly explores other applications of haustoria. The discussions of seed germination, and consequently, the haustorium development have made their way in 21st-century research. With further advancements in chemical analytic techniques and the growing realization of diverse uses of nearly every part of the plant, more attention has been attracted to the phytochemical composition of the parts, including the haustorium. The recent research on the haustorium examines haustoria molecules, their respective functions and uses, and their interactions with external factors. During the period when the haustorium converts complex nutrients in the endosperm into simple forms for the growing embryo, it is composed of varying essential sugars, amino acids, phytochemicals, bioactive compounds, macro, and micronutrients, all of which are highly beneficial for human health. It also possesses glycosides, flavonoids, phenols, and saponins, which contribute to its medicinal properties of acting against hypertension, hypercholesterolemia, hyperglycemia, obesity, as anti-allergic, anticancer, and anti-neoplastic agents, and for fighting against oxidative stress. The most recent study on the haustorium highlights how its extracts serve as an efficient antioxidant and anti-inflammatory functional food. Future studies of the Palmyra palm haustorium could offer potential applications; emphasizing the pharmaceutical, nutritional, and ethnobotanical significance.
Individual gut microbiological signature in obese diabetic spouses – case report and literature review
Authors: Piłot Magdalena , Dzięgielewska-Gęsiak Sylwia , Wolińska-Grabowska Agnieszka , Muc-Wierzgoń Małgorzata
Published: February 2024

Wstęp

Zmiany składu mikrobiomu jelitowego odgrywają istotną rolę w patofizjologii wielu schorzeń, w tym cukrzycy typu 2. Celem pracy była ocena profilu mikrobiomu jelitowego małżeństwa z otyłością i cukrzycą typu 2, mieszkającego 35 lat we wspólnym gospodarstwie domowym, pod względem stanu odżywienia, stylu życia i metod leczenia cukrzycy. Jednocześnie podjęto próbę odpowiedzi na pytanie, które czynniki mają największy wpływ na ewentualną dysbiozę jelitową.

Materiał i metody

Analizie poddano wyniki pomiarów antropometrycznych pacjentów, skład ich ciała, 24-godzinny wywiad żywieniowy, profil glikemii i próbki kału. Do ilościowego i jakościowego badania flory jelitowej w kale zastosowano metodę sekwencjonowania nowej generacji.

Wyniki

Nie stwierdzono znaczących różnic w badaniu mikrobiomu jelitowego pomiędzy małżonkami. Dominującymi gromadami bakterii były Firmicutes i Actinobacteria, podczas gdy Bacteroidetes i Proteobacteria występowały w proporcjach od 2 do 7%. Gromada Firmicutes była reprezentowana przez dominującą rodzinę Lachnospiraceae (29–31%), Ruminococcaceae (16–19%) i Streptococcaceae (3–11%). Gromada Actinobacteria była proporcjonalnie mniej liczna i reprezentowana głównie przez Bifidobacteriaceae (6–12%).

Wnioski

Być może wspólne warunki życia mają najbardziej istotny wpływ na skład mikroflory jelitowej małżonków chorych na cukrzycę, mimo różnic dotyczących płci, schorzeń współistniejących, terapii cukrzycy, stosowanej diety i zachowań zdrowotnych.
Türkiye Türkçesi Ağızlarında Birleşik İsim
Authors: EYİ Eda
Published: February 2024

Birleşik isimler, iki ya da daha fazla sözcüğün bir araya gelmesi sonucunda oluşmaktadır. Bir araya gelen sözcükler asıl anlamlarını kaybederek yeni bir anlam kazanmaktadırlar. Bundan dolayı kalıp ifadeleri oluşturmaktadırlar. Bu çalışmada, Türkiye Türkçesinde mevcut olan birleşik isim kategorisi, Türkiye Türkçesi ağızları ile karşılaştırılarak incelenmiştir. Birleşik isim kurulumu, benzerlikler ve farklılıklar bakımından hem ağızlar kendi içinde karşılaştırılarak hem diğer bölge ağızlarıyla karşılaştırılarak hem de Türkiye Türkçesiyle karşılaştırılarak verilecektir. Buradan yola çıkarak ağızlarda en çok ve en az kullanılan birleşik isim başlıkları tespit edilerek sonuç kısmında tartışılacaktır.
Tarihî ve Kültürel Yönleriyle Eski Türklerdeki Halk Ekonomisi Faaliyetlerine Genel Bir Bakış
Authors: DİKEN Hasan Ali
Published: February 2024

Bilindiği üzere, halk ekonomisi, halkın; kendi geçim kaynaklarını tesis ve temin etmek amacıyla meydana getirdiği “alternatif” üretim tarzlarının bütünüdür. Bu durumun akabinde, halk ekonomisi, dünyadaki birçok milletin tarihsel ve kültürel altyapısını dolduran bir arka planı bünyesinde barındırmaktadır. Aynı durumun Türk milleti için de geçerli olduğunu vurgulamakta yarar vardır. Tarihî süreç itibarıyla, “Türkistan” veya “Orta Asya” olarak nitelendirilen bölgede saptanan ve genel literatürde “Anav”, “Kelteminar”, “Afanesyovo” (Abakan), “Andronovo”, “Karasuk”, “Tagar” ve “Taştık” adlarıyla bilinen en eski kültürlerin; Türklerin ilk yayılma sahalarını takiben, Eski Türklerdeki ilk halk ekonomisi faaliyetlerinin temelini attıkları düşünülmektedir. Bahsedilen bağlamda, Eski Türklere ait halk ekonomisi uygulamalarının, ilgili kültürlerden intikal ettiği ve kendine özgü bir şekle girdiği bilinmektedir. Nitekim söz konusu kültürlerde de “toplayıcılık”, “avcılık”, “hayvancılık”, “ziraat” ve benzeri uygulamalar doğrultusunda teşekkül ve tekâmül eden ilk halk ekonomisi faaliyetleri; Eski Türkler eliyle daha ileri evrelere taşınmıştır. Zira malum kültürlerden sonra şahit olunan Eski Türk kültürünün mahiyetinin belirlenmesinde, halk ekonomisinin önemli bir etkisi ve katkısı vardır. Dolayısıyla Eski Türklerde cereyan eden halk ekonomisi faaliyetlerinin tarihî ve kültürel bakımlardan incelenmesi elzemdir. İlgili açıklamalara paralel olarak, bu çalışmada, Eski Türklere dair halk ekonomisi pratikleri; Hun, Göktürk ve Uygur devletlerinin hüküm sürdükleri devirler ve sahalar göz önüne alınmak suretiyle; tarihsel ve kültürel geri planlarda işlenmeye çalışılacaktır. Bahse konu minvalde, Hunlardan Göktürklere; Göktürklerden de Uygurlara kadar süregelen kimi örneklerden hareketle, halk ekonomisinin Eski Türkler arasındaki sosyokültürel ve sosyoekonomik yapıyı belirleyici ve yönlendirici nitelikleri ele alınacaktır. Sonuç itibarıyla, “normatif ekonomi” olarak tanımlanmakla beraber, alternatif bir ekonomi modelini teşkil eden ve halkbilimi çalışma kadrosunun önemli başlıklarından birini meydana getiren “halk ekonomisi” mefhumunun Eski Türklere yansımaları noktasında genel bir değerlendirmeye gidilecektir. Bu kapsamda; Eski Türklere özgü bir biçimde oluşan, gelişen, yerleşen ve yayılan geleneksel ekonomi anlayışı; eldeki mevcut örneklemler bünyesinde öne çıkarılmaya çalışılacaktır.
Private initiative as a growth factor of Book publishing activity in Russia in the last third of the 18th century
Authors: Zhitin R. M. , Topilsky A. G.
Published: February 2024

Importance. A landmark event in the history of Russia in the last third of the 18th century was the development of private printing houses, which destroyed the state and church monopoly on printing publications. The work of publishing houses played a decisive role in satisfying the spiritual needs of the broad masses of the population, contributed to the secularization of the national book culture. At the same time, the richness and diversity of fiction, educational and scientific literature, produced both in Russian and in foreign languages, thoroughly influenced the emergence and dissemination of new information and facts, increased the level of education of all segments of the reading population. Despite the existence of extensive research on the book publishing of this period, there is a well-known imbalance in the description of the activities of famous domestic printers and their foreign colleagues. Meanwhile, it was foreign specialists (I.M. Hartung, J.J. Weitbrecht, etc.) who played a key role in opening the first private printing houses in Russia. The study of their activities contributes to the increment of knowledge on the Russian book culture history, allows you to consider unknown pages of Russian book publishing and book trade.

Research Methods. The main sources of the study are the materials of the Russian State Archive of Ancient Acts (Fund 17, Fund 248), as well as legislative acts and orders of that time that influenced the book trade.

Results and Discussion. Being a characteristic feature of the development of information culture in the first half of the 18th century, censorship could not stop the transformative role of books in the history of Russia. As a result of the intensification of book printing in the country, the emergence of free book trade, the successful operation of new education models, interest in printed products has noticeably increased. Book business has ceased to be only a capital occupation and has become the property of the whole country. By allowing everyone to start printing houses at will, the state equated them with factories, which facilitated the processes of creating and developing their own printing business.

Conclusion. The activity of private book publishers in Russia in the second half of the 18th century created opportunities for the formation of the national book market, filling it with various scientific, fiction and educational literature. Thus, the printers contributed to the dissemination of the widest knowledge among the Russian population, increased the variety and quality of the literature sold.
Three-phase model for teaching reading strategies in higher education
Authors: Dolzhenkova M. I. , Medvedev N. V. , Hausmann-Ushkova N. V.
Published: February 2024

Importance. Reading in higher educationis aimed at preparation for interaction with authentic materials in professional settings. Therefore, there is a need to develop practice-oriented skills within the learning process, which requires making adjustments to the generally accepted model of organizing reading tasks. The purpose of the study is to adapt the three-phase model of text work to the use of metacognitive reading strategies in higher education.

Research Methods. Based on the analysis of scientific literature, the conditions for organizing work within the three-phase model were determined, its functional components were identified. The way of progressive integration of four reading strategies into this model was designed with taking into account their role in the realization of functional components.

Results and Discussion. Procedural functions reflecting the communicative goals of each stage were identified for each stage of the three-phase model: motivational-informational, interpretive, and reflective. Four reading strategies were integrated into this continuum. The list of strategies includes: previewing, which allows assessing the relevance of the material without direct interaction with the text; skimming, which serves as a way of determining the structure of the text; scanning, which is used for highly accurate understanding of the semantic elements of the text; and the K-W-L table, which is used for retroflexive analysis of the information learned from the text.

Conclusion. The three-phase model of reading allows integrating strategies without considerable structural changes. At the same time, the use of the indicated strategies leads to the expansion of potentially forming reading skills during task completion.
CLIL technology in teaching the English Language of Journalism
Authors: Iliina O. K.
Published: February 2024

Importance.The scientific problem is identified, which consists in the need to study tools that develop the integrated subject-language competence of graduates of non-linguistic areas of study, which underlies the successful functioning of specialists in the labor market, as well as the purpose of the study is to show the importance of the subject-language integrated approach (CLIL) in the formation of this competence.

Materials and Methods.Information about the object of study is given, which are educational materials used in teaching English journalism, as well as answers and speeches by students of advanced English language proficiency. The research methods, including observation, description, analysis and synthesis, are indicated.

Results and Discussion.The specific author’s results of the conducted research are presented, including a description of the apparatus of exercises on the topic “Manipulation and psychology” in journalism, as well as answers and speeches of students. It is noted that most of the tasks are focused on obtaining professional knowledge using the English language. A foreign language is more a means than a goal of learning here. The purely linguistic component of the educational apparatus is small. However, during the course of study, relying mainly on the material of a subjectthematic orientation, students develop all types of speech activity (speaking, listening, reading, writing) and form appropriate language skills.

Conclusion.It is proved that the most important place in the work on the topic is occupied by the preparation and presentation of the project. It is proved that subject-language integrated training is an effective method in the development of integrated subject-language competence of future journalists.