bluuebunny/crossref_metadata_2025 huggingface dataset:
Disqualification or Other Administrative Penalty as a Basis for Termination of an Employment Contract
Authors: Filchakova Svetlana
Published: January 2024

In the practice of labor relations, it is difficult to terminate the employment contract due to the application of administrative punishment to the employee, which excludes the possibility of fulfilling his duties under the employment contract. In the Labor Code of the Russian Federation, the types of such administrative punishments are not clearly defined. Only disqualification is directly named, and for other types, the criterion for their attribution to the grounds for termination of the employment contract is the legal consequence expressed in the absence of the possibility of the employee continuing the work provided for by the employment contract. At the same time, in practice, problems arise due to the fact that the application of administrative punishment is imposed automatically and does not terminate labor relations.
The author considers disqualification, notes the peculiarities of the subjects to whom this administrative punishment can be applied, as well as exclusively the judicial procedure for its application. Certain discrepancies in the regulation of disqualification as the basis for the termination of contractual relations in labor and service legislation are highlighted. At the same time, the presumption of voluntary execution of disqualification, laid down in the legislation on administrative offenses, conflicts with the provisions on recognizing disqualification as a fact that does not depend on the will of the parties, in labor legislation and legislation on the state civil service, as well as the basis for terminating the employment contract at the behest of the employer’s representative in the legislation on municipal service. The mechanism ensuring the execution of the disqualification is administrative responsibility for the disqualified person’s activities to manage a legal entity. However, the Labor Code of the Russian Federation does not classify the disqualified as persons with whom an employment contract cannot be concluded. The author refers to other types of administrative penalties, the application of which may be the basis for terminating the employment contract, administrative expulsion from the Russian Federation and administrative arrest.
It is concluded that it is advisable to specify in labor legislation all types of administrative punishments that exclude the possibility of continuing labor relations.
The Role of Internal Affairs Bodies in the Prevention of Corruption Crimes
Authors: Sidorova Ekaterina
Published: January 2024

In the modern period, our state and society are striving to eradicate corruption in all its manifestations. The social danger of corruption is obvious. It is safe to say that corruption is one of the most serious threats to the national security of the country. In this regard, the activities of special bodies authorized to combat corruption crimes have great preventive potential, the key place among which is occupied by the internal affairs bodies. The purpose of this work is to determine the place of internal affairs bodies in the system of countering corruption-related offenses. Based on the current legislation, the author reveals the concept of «corruption». Using up-to-date official statistical data, the author presents quantitative and qualitative indicators of corruption offenses in the Russian Federation and concludes that the number of detected corruption crimes is growing annually, which indicates the need for the subjects to intensify the prevention of corruption crimes, including internal affairs agencies, those forces and means that are directed to fight corruption in the our country. Determining the place of the internal affairs bodies in the system of countering corruption-related offenses, the author names the main subjects of the prevention of these crimes. At the same time, the special role of the internal affairs bodies in solving such a national task as the fight against corruption is determined by the legal and organizational foundations of combating corruption that have developed in the system of the Ministry of Internal Affairs of Russia. Special attention is paid in the article to the coverage of the main anticorruption measures that should be implemented by employees of the internal affairs bodies. The author also reveals the specifics of the activities of individual divisions of the internal affairs bodies in the prevention of corruption offenses, primarily the economic security and anti-corruption units of the territorial internal affairs bodies. In conclusion, the author states that police officers, performing the function of preventing corruption-related crimes and administrative offenses, are engaged in ensuring not only public, but also national security in general, which indicates the special role of internal affairs bodies in preventing corruption crimes.
Rendition or Extradition: Terminology Issue
Authors: Smolkova Iraida
Published: January 2024

The article addresses the terminological problem regarding the relationship between the terms “rendition” and “extradition”, draws attention to the rather contradictory development of legislation in this area, the ambiguous interpretation of these terms and their understanding in the legal literature. The author examines the history of the emergence of the term “extradition”, draws attention to the fact that in domestic legislative practice and scientific literature both in the pre-revolutionary and at present, the term “extradition” has not taken root, although it is used in some publications. The article criticizes the use in the legal literature of the phrases “extradition of a criminal” and “extradition of a person who has committed a crime” due to their contradiction to the principle of presumption of innocence. Taking into account the fact that in the first form of extradition – the extradition of a person for criminal prosecution, the issue of his guilt is not discussed, this issue is resolved by the law enforcement agencies of the state to which this person is extradited. The “extradition of a person who has committed a crime” can be discussed in a certain sense in the second form of extradition – extradition for the execution of a sentence, because in this case the person was found guilty by a court verdict that entered into legal force.
In the theory of criminal proceedings, there were two diametrically opposite approaches to the issue of the concept and relationship of the terms “rendition” and “extradition”, the first consists in their fundamental difference, the second – in their synonymy. The author adheres to the second approach, makes arguments in his defense.
Formation of secure programming methods for development web applications
Authors:   Novosibirsk State Technical University, Russian Federation, Arkhipova Anastasia B. , Listarov Roman E. ,   Novosibirsk State Technical University, Russian Federation
Published: January 2024

Today, cyberphysical systems often become targets of targeted cyberattacks, including the exploitation of vulnerabilities in software operating in such systems. Vulnerable software can be used to distribute malicious software, steal or disclose confidential data, affect protected information in violation of established rights, leading to destruction, destruction, distortion or malfunction of automated systems in which this software operates. Determining the methodology for the secure development of web applications is the most important stage in the development of a comprehensive protection system for the object of informatization. This article proposes technologies to improve the level of security provided by the BSIMM method of secure programming, with the help of which it is possible to ensure the proper level of protection for each web application, depending on the sensitivity of the information processed.
Risk and prognosis of second cutaneous melanoma after radiotherapy for breast cancer: A population-based analysis
Authors: Luo Tianxin , Zhang Yani , Chen Tianliang , Cai Yanxia , Yang Zheng
Published: January 2024

Radiation therapy (RT), a primary treatment for breast cancer (BC), may be associated with increased non-BC tumor risk. We aimed to examine second cutaneous melanoma (SCM) risk in BC patients who underwent RT and to assess their survival outcomes. Data from 520,977 BC patients diagnosed between 1973–2018 were collected from the Surveillance, Epidemiology, and End Results (SEER) database. Cumulative SCM incidence was estimated using the Fine–Gray competing risk model. Poisson regression analysis was conducted to calculate the standardized incidence ratio (SIR) and estimate the SCM relative risk in patients who underwent RT compared to those who did not. Overall survival (OS) and cancer-specific survival (CSS) were assessed using the Kaplan‒Meier method. Among the 520,977 BC patients, 243,676 (46.8%) underwent surgery and RT, while 277,301 (53.2%) only underwent surgery. Our results suggest that BC patients receiving RT had a higher SCM risk than those who did not (hazard ratio [HR] 1.40; 95% confidence interval [CI] 1.30-1.51; P < 0.001). SCM incidence was also higher in BC patients treated with RT than in the general US population (SIR 1.12; 95% CI 1.05-1.19; P < 0.05). However, SCM patients who received RT had a significantly higher 10-year survival rate than those who did not receive RT (14.90% vs 5.94%; P < 0.001). No significant difference was found in 10-year OS or 5-year CSS between SCM following RT and only primary cutaneous melanoma (OPCM), but SCM patients who did not receive RT had a significantly lower 10-year OS, with no significant difference in CSS. This study suggests an increased SCM likelihood in BC patients due to RT, although the overall risk is minimal.
Дневник переводчика Посольского приказа Кристофа Боуша (1654-1664)
Authors: Русаковский Олег
Published: January 2024

Издание предлагает вниманию читателей комментированный перевод дневниковых записей, которые переводчик на русской службе Кристоф (в православии — Василий) Боуш тайно вел на немецком языке в 1654 – 1664 гг. Автор рассказывает о боевых действиях в ходе русско-польской войны 1654 – 1657 гг., поведении русских войск на завоеванных территориях, судьбе польских пленных в России, о событиях при царском дворе, порче монеты, восстаниях и политической борьбе в России и польско-литовском государстве, о пожарах, вспышках чумы и прочих бедствиях. Подробно описываются приемы иностранных послов в Кремле и переговоры русских дипломатов на съездах с польскими и шведскими представителями. Хотя большая часть сообщений, несомненно, отражает взгляд из Москвы, автор «Дневника», сам прошедший русский плен, не скрывал ни своих сложных чувств к «московитам», которым принужден был служить, ни сочувствия к "полякам". "Дневник" содержит ценные сведения по истории Восточной Европы XVII в., а также является уникальным свидетельством того, как иноземец на царской службе воспринимал политические и культурные реалии русского государства и его внешней политики. Книга адресована как историкам, культурологам, филологам, так и широкому кругу читателей.
The impact of the body micro-environment on female infertility
Authors: Rosita Verteramo , Matteo Pierdomenico , Giulia Gerolin , Pantaleo Greco , Carmelia Milano
Published: January 2024

Infertility influences 15% of reproductive-aged couples in the world and the same percentage has been counted in Italy. Male and female causes of infertility are identified in 20% - 30% and 20% - 35% of couples, respectively; in 10% - 20% of cases, no cause is found. Until the last decade, a lot of studies have analyzed both modifiable factors (tobacco, alcohol, diet factors, overweight, infections) and non-modifiable factors (parental age, low ovarian reserve, etc.). Probably there is a connection between modifiable and non-modifiable causes of infertility, that together increase the failure of reproduction. This review aims to analyze the influence of the microenvironment in the female genital tract, particularly to highlight the current literature, published in Italy, on reproductive tract microbiome in different anatomical locations, vagina, endometrium, Fallopian tubes, the intestinal microbiome, and the possible interaction between such microbial communities and infertility. Finally, based on the data presented in this review, we try to encourage future perspectives and research directions in Italy.
Apua allianssista?
Authors: Lähdeniemi Milla , Anttila Anna , Järvensivu Anu , Leinikki Sikke , Pyykkönen Miikka , Schalin Anton
Published: January 2024

Taiteilija-allianssilla pyritään helpottamaan luovien alojen epävarmoissa ja lyhyissä työsuhteissa toimivien freelancereiden työolosuhteita tarjoamalla osin julkisin varoin ammatillista, taloudellista ja sosiaalista turvaa työsuhteiden muodossa. Allianssimallin käyttöönotolle ei ole aikaisemman selvityksen mukaan Suomessa oikeudellisia esteitä, mutta silti mallista ei ole toteutettu edes kokeilua. Tarkastelemme artikkelissamme, millainen Koskisen selvityksessä ehdotettu allianssimalli on ja minkälaista kritiikkiä mallille esitettiin kulttuurialan sidosryhmien edustajilta pyydetyissä lausunnoissa. Tarkastelemme, miten allianssille kohdistettu kritiikki näyttäytyy suhteessa tutkimuksen tunnistamiin taiteen työelämän olosuhteisiin sekä taiteen ammattilaisten näkemyksiin niiden parantamisesta. Empiirisen aineiston analyysimenetelmänä sovellamme sisällönanalyysiä. Analyysissä oli mukana 33 lausuntoa kulttuurialan edunvalvojilta (n=13), valtionhallinnon edustajilta (n=16), työntekijöiden keskusjärjestöiltä (n=3) ja työnantajien keskusjärjestöltä (n=1). Allianssimallista on esitetty kolmivuotista kokeilua näyttelijöille, tanssijoille ja muusikoille. Lausunnoissa allianssin kokeilemista pitivät kannattavana kuusi kulttuurialan edunvalvojaa, yksi valtionhallinnon edustaja ja yksi työntekijöiden keskusjärjestö. Vaikka allianssia kritisoitiin, vain viiden kaikista 33 lausunnonantajasta voi tulkita selkeästi vastustavan allianssia tai siitä suunniteltua pilottia. Yksi kulttuurialan edunvalvoja suhtautui kokeiluun kriittisesti, kolme valtionhallinnon edustaa sekä yksi työnantajien keskusjärjestö olivat mallia vastaan. Lausunnoissa näkemykset erosivat erityisesti allianssityön työsuhteeseen, allianssityön sisältöihin ja valintakriteereihin liittyen. Tasa-arvoon ja yhdenvertaisuuteen liittyen kulttuurialan edustajasta 54 % ja valtionhallinnon edustajaista 44 % olivat yhteneväisellä linjalla: allianssia ei nähty yhdenvertaisena eikä tasa-arvoa lisäävänä. Kulttuurialan edustajien(69 %) mukaan allianssikokeilun onnistuessa malli tulisi harkita laajennettavaksi esittävän taiteen suunnitteluun, sirkustaiteilijoihin, musiikintekijöihin, kirjailijoihin, säveltäjiin ja kuvataiteilijoihin. Kulttuurialalla kaivataan ratkaisuja alalla pitkään vallinneisiin ongelmiin. Kritiikkiä annettiin erityisesti yhdenvertaisuudesta, jonka puute on aito ongelma. Ongelma voisi kuitenkin olla ratkaistavissa kansainvälisiä malleja seuraamalla. Mallin todellinen potentiaali voidaan todentaa vasta kokeilun kautta.
Lise öğrencilerinin gözünden iyi bir tarih öğretmeni
Authors: Beştepe Ayşe , Yazıcı Fatih
Published: January 2024

Öğretmenlerin hangi niteliklere sahip olması gerektiği, özellikle Shulman’ın milat niteliğindeki çalışmalarıyla birlikte eğitim araştırmalarının sıkça tartışılan konularından biri haline gelmiştir. Fakat tarih öğretiminin amaç ve içeriğinde, 20. yüzyılın ikinci yarısından bu yana yaşanan dönüşüme rağmen, tarih öğretmenlerinin sahip olması gereken niteliklere dair yapılan çalışmaların son derece sınırlı olduğu görülmektedir. Bu araştırmada lise öğrencilerine göre, iyi bir tarih öğretmeninin sahip olması gereken niteliklerin ortaya konulması amaçlanmıştır. Çalışmada nitel araştırma desenlerinden durum çalışmasından yararlanılmıştır. Araştırmanın çalışma grubunu, Tokat il merkezinde yer alan iki farklı ortaöğretim kurumunun 12. sınıflarında öğrenim gören 108 lise öğrencisi oluşturmaktadır. Araştırma verileri, araştırmacılar tarafından geliştirilen açık uçlu soru formu ile toplanmıştır. Elde edilen veriler ise içerik analizine tabi tutulmuştur. Araştırmada lise öğrencileri, tarih derslerinde kullanılan yöntemlerin zenginleştirilmesi gerektiğine vurgu yapmış, tarih öğretmenlerinin kullanabilecekleri yöntem ve tekniklere; görsel materyal kullanımı, alan gezileri, aktif öğrenme stratejileri, örnek olay kullanımı gibi pek çok örnek vermişlerdir. Katılımcılar tarafından tarih öğretmenlerinin sıkıcı olmaması ve anlatım gücünün yüksek olması gerektiğine yapılan vurgu ise dikkat çekmektedir. Katılımcılara göre iyi bir tarih öğretmeni içerikte Türk tarihine, özellikle de Osmanlı ve Cumhuriyet tarihine ağırlık vermelidir. Derslerinde ulusal ve kültürel değerlerin kazandırılmasına önem vermeli, bunu da tarafsız kalarak sağlamalıdır. Araştırma sonunda öğrencilerin tarih öğretmenlerinde görmek istedikleri niteliklerin pek çoğunun, çağdaş tarih öğretim yaklaşımlarının öğretmenlere yükledikleri sorumluluklarla yakından ilişkili olduğu görülmüştür.
Histological image quantification of picrosirius red stained skeletal muscle sections v1
Authors: Hildyard John
Published: January 2024

Picrosirius Red (PSR) staining of skeletal muscle tissue sections permits histological evaluation of muscle fibrosis: muscle fibres are stained a vivid picric acid yellow, while connective tissue is stained a vibrant Sirius red. Connective tissue can also be visualised via brightfield, fluorescence or polarized light microscopy, but no standard approach for image quantitation is currently employed. This protocol provides a method to robustly quantify images collected from such stained muscle sections, using the Hue/Saturation/Brightness (HSB) colour-space, integrated into a high-throughput semi-automated macro written for the open-source imagej distribution, Fiji. Note: PSR staining is usually restricted to formalin fixed paraffin-embedded (FFPE) tissue: staining of fresh frozen tissue uses a method developed by Hadi et al (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162624/): an optimised version of this protocol is also included here.
Stereotaxic Injections and Implants v2
Authors: Tang Jonathan
Published: January 2024

Methods for Stereotaxic injections and implants from Tang et al 2023.
Fiber Photometry Acquisition v1
Authors: Tang Jonathan
Published: January 2024

Fiber Photometry Acquisition parameters and protocol for Tang et al 2023.
Editorial Note, Navigating Geopolitical Shifts and Turbulence: A Multifaceted of International Relations
Authors:   Universiti kebangsaan Malaysia, Othman Zarina , Mat Bakri ,   Universiti Utara Malaysia, Azman Muhammad Danial ,   Universiti Malaya
Published: January 2024

The year 2023, which is about to draw its curtain, has recorded various geopolitical changes and challenging issues due to complex interactions among various parties, which require a thorough solution for the benefit of humanity. The events of the Russia-Ukraine War, the conflict in the Middle East that is heating up, in addition to climate change that results in various catastrophes are among some bitter facts as a hard lesson for all of us. Parallel to this development, this edition of SINERGI covers a wide range of topics, such as the US-China competition and democratic leadership in the context of ASEAN, as well as China’s Belt and Road Initiative and its effects on Kazakhstan and Turkmenistan. The collection also examines the geopolitical significance of locations such as the Strait of Hormuz and reassesses historical personalities like the case of the Empress Dowager Cixi. Overall, this compilation provides valuable, insightful information about the intricacies of international politics, economic manoeuvres, and regional security, which presenting a wide range of viewpoints to guide scholarly discussion and policy.
Externalisation of Domestic Economic Constraints: China’s Spatial Fix in Kazakhstan and Turkmenistan
Authors:   Balochistan University of IT, Engineering and Management Sciences (BUITEMS), Khan Hidayatullah
Published: January 2024

Growing capital over-accumulation and excessive industrial production have forced policymakers in Beijing to search for profitable outlets overseas. The Belt and Road Initiative (BRI), which focuses on infrastructure connectivity projects across Eurasia, reflects these efforts. This paper theorises BRI as a spatial fix aimed at overcoming the recurring problem of over-accumulation of capital. This paper focuses on BRI-led projects in Kazakhstan and Turkmenistan. By conducting unstructured interviews with experts and examining projects, this paper found that BRI-led projects in Kazakhstan and Turkmenistan not only provided a new geographical space and under-saturated market for Chinese surpluses but also created the demand for Chinese State-Owned Enterprises (SOEs) which were facing a decline in returns. This paper also found that through elements such as non-competitive bidding, embedded conditionality, and double preferential loans, China has successfully stimulated overseas demand for its surpluses. The study, therefore, concludes that BRI-led projects in Kazakhstan and Turkmenistan serve as a spatial fix for China.
ASEAN's Role and Future Economic Cooperation Under the US-China Rivalry: The Quest for Effective Democratic Leadership
Authors:   Universitas Indonesia, Tobing Fredy B. L. , Aristama Ferga ,   Universitas Indonesia
Published: January 2024

Amid the US-China rivalry, the ASEAN role and future economic cooperation are uncertain. Deploying a qualitative approach based on documents as sources of data, this study aims to suggest democratic leadership as an intervening variable and examines future possibilities of the ASEAN role and economic cooperation under the US-China rivalry. There are three ASEAN's role future possibilities under the US-China rivalry: the honest broker (best-case scenario), a partial mediator (moderate-case scenario), and a dysfunctional organisation (worst-case scenario). The gradations linearly demonstrated an interlinked connection between the cooperation engagement and outcome possibilities. This study found that the best-case prospect, "an honest broker" could be materialised by implementing democratic leadership, an equally distributed, empowered, egalitarian decision-making kind of leadership determined by willingness, capacity, and acceptance. It could optimally encourage internal economic development and effectively manage cooperation with both parties through the distribution of responsibility, group member empowerment, and assisting all members in decision-making.
Russia-Ukraine Relations After the Fall of the Soviet Union: From Minor Disputes to the Battlefield
Authors:   The National Anti-Drugs Agency, Ministry of Home Affairs, Malaysia, Abdul Malik Maifuza , Rahman Riki ,   Universiti Tun Hussein Onn Malaysia
Published: January 2024

After the end of the Cold War and the dissolution of the Soviet Union in 1991, Ukraine and Russia established good cooperation in various aspects despite some shifts in domestic issues. Ukraine adopted a policy of neutrality in its administration because it needed cooperation from various parties, including Russia and the West. However, everything changed when Ukraine expressed its desire to join NATO in 2008. This desire was welcomed by NATO but opposed by Russia, leading to an ongoing conflict with Ukraine, including the annexation of Crimea and the occupation of Donbas. This study aims to explain the development of the conflict between Russia and Ukraine and identify the triggering factors between the two countries. The library method was used to gather secondary information from books, journals, reports, newspapers, and credible Internet sources. The study found that Russia's attack on Ukraine was driven by the need to ensure its survival and sovereignty against major powers such as the US and NATO, which were increasingly approaching the Eastern Europe region. The study also found two factors that triggered the conflict between Russia and Ukraine, namely internal and external factors. External factors such as the expansion of power and influence of the United States, the European Union, and NATO approaching Russia's borders, as well as Russia's geo-economic power beyond its borders, played a role in triggering the conflict. Meanwhile, internal factors include the presence of Russian elite groups that play a role in making important state decisions and Russia's formidable military capabilities.
Methodology for the Synthesis of a Multicopter Controller Acting as a Swarm Agent using the Thermal Motion Equivalent Method
Authors: Heiss E. A. , Morozov O. O. , Kozyr A. V. , Efromeev A. G.
Published: January 2024

The paper is dedicated to the development of a method for the synthesis of the control system of a swarm multicopter. The motion of the agents in the swarm is organised by the thermal motion equivalent method. The idea of the method is the behavioral similarity of the thermal motion of the atoms by the agents. In the practical implementation of the thermal motion equivalent method, it is important to ensure constancy of velocity and isotropy of agent dynamics. Violating these properties will cause the swarm to fail a mission, such as an area exploration, by reducing the RMS speed of the agents to zero. The proposed solution to these problems is to synthesize a modal controller for the agent-boundaries test system for the slowest control channel, thereby ensuring RMS velocity constancy of the agent. The synthesized controller is used as a filter in the fast-acting channels, the second horizontal channel and the vertical channel. In the fast-acting channels, an additional filter is proposed to bring their dynamics to the slowest channel, thereby ensuring isotropy. The inclusion of a limit on the maximum length of the equivalent field vector ensures isotropy. The synthesis was carried out using a simplified multicopter dynamics mathematical model, obtained with small UAV deviations from the vertical and without considering the Coriolis force. The methodology for the synthesis of a multicopter control system for functioning as part of a swarm is developed using the obtained results. Numerical simulation results of both a single vehicle in closed space and a swarm using a more complete nonlinear dynamic quadcopter model are presented. The proposed method has the advantage of simple synthesis using a linear model. Numerical simulation results confirm the operability of the developed methodology.
Instagram as a tool for developing teenage reading culture
Authors:   Taras Shevchenko National University of Kyiv, Kyiv, Ukraine, Kovalova Oleksandra
Published: January 2024

This article presents the findings of a media monitoring study, focusing on effective strategies for shaping and promoting a reading culture on Instagram. The study also includes the development of recommendations for interested stakeholders. Media monitoring for the analysis of Ukrainian bookstagram was conducted on the LOOQME Hub platform from October 2022 to August 2023. A total of 1480 publications were analyzed, encompassing accounts of both private individuals and corporate Instagram pages. The study revealed a consistent growth in the dynamics of mentions of the hashtag #українськийбукстаграм (eng. Ukrainian boostagram) during the research period. It indicates sustained interest and activity within the bookstagram reading community. The typology of bookstagram publications is categorized into three main groups: posts, comments, and comment replies. This classification highlights diverse interaction strategies employed by bookstagrammers with their audience. The study identified the most active accounts in Ukrainian bookstagram. Average visitation metrics of bookstagrammer accounts suggest consistent interest and activity from the audience throughout the research period. The findings confirm the high communicative potential of bookstagram and underscore its significance in the development of reading culture among Ukrainian adolescents. The analysis results can be applied for enhancing media literacy, fostering critical thinking, and are valuable in both pedagogy and the commercial interests of the publishing industry.
Comparative analysis of the effectiveness of methods for constructing quite interpretable linear regression models
Authors: Bazilevskiy M.P.
Published: January 2024

Previously, the author managed to reduce the problem of constructing a quite interpretable linear regression, estimated using ordinary least squares method, to a mixed-integer 0-1 linear programming problem. In such models, the signs of the estimates correspond to the substantive meaning of the factors, the absolute contributions of the variables to the overall determination are significant, and the degree of multicollinearity is small. The optimal solution to the formulated problem can also be found by generating all subsets method. The purpose of this article is to conduct a comparative analysis of the effectiveness of these two approaches. To conduct computational experiments, 5 sets of real statistical data of various volumes were used. As a result, more than 550 different mixed-integer 0-1 problems were solved using the LPSolve package under different conditions. At the same time, the efficiency of solving similar problems using the generating all subsets method in the Gretl package was assessed. In all experiments, our proposed method turned out to be many times more effective than the generating all subsets method. The highest efficiency was achieved in solving the subset selection problem from 103 variables, solving each of which by generating all subsets would require estimating approximately 2103 (10.1 nonillion) models, which a conventional computer would not have been able to cope with in 1000 years. In LPSolve, each of these problems was solved in 32 – 191 seconds. The proposed method was able to process a large data sample containing 40 explanatory variables and 515,345 observations in an acceptable time, which confirms the independence of its effectiveness from the sample size. It has been revealed that tightening the requirements for multicollinearity and absolute contributions of variables in the linear constraints of the problem almost always reduces the speed of its solution.
Formulasi body lotion dari ekstrak lamun dan gonad bulu babi
Authors: Ningrum Reza Hidayah , Asih Eka Nurrahema Ning , Ni’amah Siti Nihayatun , Badriyah Lailatul , Mardiyanti Yuniar , Wulansari Destin Retno
Published: January 2024

Inovasi body lotion pada dekade ini telah banyak dimodifikasi mengandung senyawa untuk mencegah dampak paparan sinar ultraviolet berupa radikal bebas yang berbahaya bagi kulit. Bahan alami dari laut yang berpotensi sebagai tabir surya pada body lotion adalah ekstrak lamun (Enhalus acoroides) dan gonad bulu babi (Diadema setosum). Tujuan penelitian adalah menentukan kombinasi ekstrak lamun dan gonad bulu babi terbaik sebagai sediaan body lotion berdasarkan informasi kandungan senyawa metabolit sekunder lamun sebagai bahan dasar, indeks kelayakan fisik, dan nilai sun protection factor (SPF) terbaik. Penelitian ini dilakukan dengan melihat perbedaan perbandingan lamun dan gonad bulu babi yaitu F1 (2:1), F2 (1:2), F3 (3:3) dan kontrol F0 (0:0). Analisis yang dilakukan dengan metode uji dan observasi meliputi uji fitokimia, uji organoleptik, dan uji nilai SPF sediaan secara in vitro menggunakan Spektrofotometri UV-Vis. Hasil penelitian menunjukkan bahwa senyawa fitokimia yang terdeteksi pada ekstrak lamun diantaranya flavonoid, triterpenoid, saponin. Sediaan body lotion layak digunakan dengan indeks iritasi merasa tidak gatal tertinggi pada F3 sebanyak 17 panelis. Nilai SPF tertinggi yaitu F1 sebesar 12,2 sedangkan nilai terendah pada F0 sebesar 3,5 sehingga sediaan F1 berpotensi sebagai tabir surya untuk proteksi sinar UV-B maksimal.
Profil asam amino Turbinaria ornata dan Ulva reticulata dari Perairan Moudolung Sumba Timur
Authors: Meiyasa Firat , Ranjawali Erwin , Tuarita Mirna Zena , Tarigan Nurbety
Published: January 2024

Rumput laut merupakan sumber hayati yang memiliki potensi untuk dikembangkan dalam bidang pangan, salah satunya adalah bahan tambahan pangan. Komposisi kimia dan profil asam amino dari rumput laut perlu dikaji lebih lanjut. Penelitian ini bertujuan untuk menentukan komposisi kimia dan profil asam amino rumput laut yang berpotensi sebagai kondimen atau bumbu penyedap. Bahan baku meliputi Turbinaria ornata (alga cokelat) dan Ulva reticulata (alga hijau) diperoleh dari Perairan Moudolung, Sumba Timur. Sampel dikeringkan menggunakan sinar matahari selama 2-3 hari, ditepungkan dan dianalisis kadar air, abu, lemak, protein, serat kasar, dan karbohidrat (by difference) serta profil asam amino. Hasil penelitian menunjukkan kedua jenis tepung rumput laut memiliki kadar air 13,34-15,40%, abu 19,20-36,76%, lemak 2,28-5,83%, protein 5,08-5,57%, karbohidrat 42,54-54,00%, dan serat kasar 25,00-27,75%. Profil asam amino kedua jenis rumput laut terkonfirmasi ada 15 jenis di antaranya adalah asam amino esensial (fenilalanin, isoleusin, valin, arginin, lisin, leusin, treonin, dan histidin) dan non esensial (serin, asam glutamat, alanin, glisin, asam aspartat, tirosin, dan prolin). Asam glutamat dan asam aspartat merupakan asam amino dominan dibandingkan asam amino lainnya. Rumput laut T. ornata dan U. reticulata yang berasal dari Perairan Sumba Timur dapat dimanfaatkan sebagai kondimen atau bumbu penyedap.
Profil asam lemak minyak dari jeroan ikan nila dan mas dengan rasio pelarut yang berbeda
Authors: Suseno Sugeng Heri , Pari Rizfi Fariz , Ibrahim Bustami , Ramadhan Rizki Tri Kurnia , Listiana Desi , Nurjannah Farah , Adha As Syaffa Amalia
Published: January 2024

Produk hasil samping ikan nila dan mas dapat dimanfaatkan menjadi minyak ikan dengan metode ekstraksi yang tepat. Penelitian ini bertujuan untuk menentukan rasio pelarut aseton dan minyak ikan terhadap parameter oksidasi, bilangan iod, dan profil asam lemak minyak ikan nila dan mas. Penelitian ini menggunakan metode eksperimen rancangan acak lengkap (RAL) dengan taraf perlakuan rasio pelarut aseton dan minyak 3:1, 4:1, 5:1, 6:1, dan 7:1(v/v). Parameter yang dianalisis dalam penelitian ini meliputi proksimat, asam lemak bebas, bilangan asam, bilangan peroksida, p-anisidin, total oksidasi, bilangan iodin, dan profil asam lemak. Nilai omega-3 pada ikan nila dan mas berturut-turut adalah 1,20% dan 1,53%. Perlakuan terbaik dengan rasio pelarut dan minyak adalah 5:1 (v/v) yang ditentukan oleh hasil uji bilangan iod tertinggi. Peningkatan nilai omega-3 minyak ikan nila sebesar 1,76% dan pada ikan mas sebesar 0,78% masing-masing menjadi 2,96% dan 2,31%.
Karakteristik organoleptik dan kimia kue kering dengan penambahan daging dan tepung keong bakau (Telescopium telescopium)
Authors: Rieuwpassa Fredrik , Br. Silaban Bernita , Kelanohon Syahrul Rajak
Published: January 2024

Kue kering adalah kue berukuran kecil, renyah, tipis, datar (gepeng), memiliki rasa manis dan asin gurih. Kue kering dapat dijadikan salah satu alternatif makanan selingan yang praktis dan sehat atau bersifat fungsional apabila di dalam proses pembuatannya ditambahkan bahan yang dapat memberikan efek positif bagi kesehatan tubuh. Penambahan daging keong bakau menjadi pilihan untuk memperoleh kue kering yang bergizi dan dapat diterima oleh konsumen. Penelitian ini bertujuan untuk menentukan karakteristik kimia dan organoleptik terbaik dari kue kering dengan penambahan daging keong bakau (Telescopium telescopium). Perlakuan yang digunakan pada penelitian ini meliputi perlakuan tanpa penambahan daging cincang dan tepung keong bakau sebagai perlakuan kontrol (A0), penambahan daging cincang keong bakau 15% (A1),  tepung keong bakau 15% (A2), campuran daging cincang keong bakau 7,5% dan tepung keong bakau 7,5% (A3). Parameter yang diamati dalama penelitian ini meliputi parameter kimia yaitu kadar air, abu, protein, lemak, karbohidrat secara by difference dan mineral kalsium. Parameter fisik yang diamati meliputi ketampakan, rasa, bau, dan tekstur. Pengolahan data dilakukan menggunakan analisis sidik ragam (ANOVA) dengan tiga kali ulangan dan uji lanjut Duncan. Hasil penelitian menunjukkan bahwa karakteristik kimia kue kering dengan penambahan daging keong bakau menghasilkan kadar air berkisar antara 4,92-6,81%; lemak 20,7-27,68%;  abu 2,4-3,06%;  protein 8,46-15,46%; karbohidrat 50,6-58,3% dan mineral kalsium 0,88-6,29 ppm. Karakteristik organoleptik berkisar antara tidak suka sampai sangat suka dengan nilai tertinggi pada perlakuan penambahan daging cincang keong bakau 15% (A1). Perlakuan A1 dapat direkomendasikan sebagai perlakuan terbaik dalam pembuatan kue kering dari daging dan tepung keong bakau dari segi nilai gizi dan organoleptiknya.
Purifikasi fikosianin dari Spirulina platensis hasil intervensi kemangi (Ocimum basilicum) pada konsentrasi amonium sulfat berbeda
Authors: Yuliani Yuliani , Agustini Tri Winarni , Dewi Eko Nurcahya , Afifah Diana Nur
Published: January 2024

Spirulina platensis merupakan kelompok ganggang hijau biru berserabut yang mengandung senyawa fikobiliprotein. Fikosianin merupakan komplek pigmen-protein paling tinggi pada fikobiliprotein. Fikosianin memiliki nilai komersial yang paling dominan pada industri makanan, kosmetik maupun obat-obatan. Purifikasi fikosianin merupakan suatu proses peningkatan kemurnian dan salah satu cara untuk meningkatkan aktivitas spesifik fikosianin. Ocimum basilicum atau kemangi adalah tumbuhan yang mengandung azulene yang merupakan senyawa hidrokarbon aromatik yang berwarna biru. Tujuan penelitian ini adalah untuk menentukan pengaruh intervensi kemangi dan tingkat saturasi pengendapan amonium sulfat pada proses purifikasi fikosianin S. platensis terhadap indeks kemurnian, kandungan fikosianin, recovery, dan total protein. Metode purifikasi fikosianin yang digunakan adalah metode multistep yang terdiri dari ekstraksi S. platensis tanpa intervensi dan intervensi kemangi, pengendapan dengan amonium sulfat pada tingkat saturasi (0-20%), (20-50%), (50-70%), (70-90%), dan ultrafiltrasi (DF/UF). Hasil penelitian menunjukkan tingkat saturasi terbaik pada tahap purifikasi dengan pengendapan amonium sulfat untuk sampel tanpa intervensi sebesar 50% dan intervensi sebesar 70%. Fikosianin hasil intervensi kemangi memiliki nilai kemurnian dan kandungan fikosianin yang lebih tinggi dibandingkan sampel tanpa intervensi pada setiap tahapan purifikasi. Nilai kemurnian pada tahap purifikasi akhir sebesar 2,54 AU untuk sampel tanpa intervensi dan 2,57 AU untuk sampel intervensi kemangi. Perlakuan intervensi maupun tanpa intervensi daun kemangi pada  S. platensis dapat menurunkan nilai recovery dan total protein pada setiap tahap purifikasi.
Karakteristik kimia dan keamanan mikroba tepung ikan teri hitam (Stolephorus commersonii)
Authors: Litaay Christina , Indriati Ashri , Andriansyah Raden Cecep Erwan , Novianti Fithria , Purwandoko Pradeka Brilyan , Rahman Nurhaidar , Nuraini Laela , Rahman Nurhamidar , Hidayat Taufik
Published: January 2024

Ikan teri hitam (Stolephorus commersonii) merupakan jenis ikan pelagis kecil yang bernilai gizi tinggi. Ikan teri hitam memiliki nilai ekonomi yang tinggi, namun pemanfaatannya masih bersifat tradisional. Peningkatan nilai tambah ikan teri hitam dapat dilakukan melalui diversifikasi produk dalam bentuk tepung ikan. Penelitian ini bertujuan untuk menentukan karakteristik tepung ikan teri hitam berdasarkan komposisi kimia, kandungan mineral, dan cemaran mikroba. Metode penelitian yang digunakan adalah metode eksperimen pengolahan tepung ikan menggunakan modifikasi media perendaman air pada suhu 25oC, selama 15 menit. Parameter yang diuji yaitu analisis proksimat, mineral (besi, magnesium, dan kalsium), dan cemaran mikroba (Angka Lempeng Total (ALT), kapang khamir, dan Escherichia coli). Hasil analisis menunjukkan bahwa tepung ikan teri mengandung kadar protein 70,16%, air 9,62%, abu 14,85%, dan lemak 4,55%. Kadar besi (5,99 mg/g), magnesium (163,565 mg/g), dan kalsium (6179,95 mg/g). Cemaran mikroba Angka Lempeng Total (ALT) sebesar 1,15 koloni/g, kapang khamir <10 koloni/g, dan Escherichia coli negatif.
Karakteristik hedonik dan kimia cendol instan ikan gabus dengan formulasi sumber karbohidrat lokal berbeda
Authors: Dewita Dewita , Sidauruk Santhy Wisuda , Desmelati Desmelati , Hidayat Taufik
Published: January 2024

Cendol merupakan minuman tradisional Indonesia yang dapat dikonsumsi oleh semua kalangan. Cendol memiliki kekurangan, yaitu kandungan gizi rendah karena didominasi tepung beras dan kadar air yang tinggi. Peningkatan kandungan gizi dan pengurangan kadar air pada cendol dapat dilakukan melalui fortifikasi 1,25% tepung ikan gabus dan diversifikasi berbagai sumber karbohidrat lokal untuk mensubstitusi tepung beras menggunakan metode pengeringan oven. Tujuan penelitian yaitu menentukan komibinasi tepung lokal terbaik pada cendol instan yang difortifikasi tepung ikan gabus berdasarkan parameter hedonik dan kimia. Produksi tepung ikan menggunakan metode steaming dengan parameter uji rendemen dan proksimat. Produksi cendol instan ikan gabus menggunakan metode pengeringan oven dengan parameter uji hedonik dan kimia. Perlakuan rasio sumber karbohidrat lokal yang digunakan, yaitu tepung beras:tepung sagu:tepung porang C1 (3:1:0), C2 (3:0:1), C3 (2:1:1), C4 (0:2:2), C5 (0:1:3), dan C6 (0:3:1). Hasil penelitian menunjukkan bahwa tepung ikan gabus memiliki rendemen 15,23% dan kadar protein sebesar 84,42±0,53%. Secara keseluruhan, cendol instan dengan formulasi tepung beras dan tepung sagu (C1) merupakan cendol instan terbaik. Tingkat kesukaan panelis terhadap penilaian warna, aroma, tekstur, dan rasa cendol instan ikan gabus memilih lebih menyukai pada perlakuan C1 dengan karakteristik kimia terutama protein tertinggi sebesar 15.48±0.13%, diikuti kadar air yang rendah sebesar 11.45±0.16%.
Semantic Data Quality Assessment
Authors:   , Razzaghi Hanieh , Greenberg Jane
Published: January 2024

Introduction: One of the foundations of research is that the underlying data are of sufficient quality to yield valid results. This is particularly important where research makes secondary use of data derived from electronic health records (EHR) or other clinical data, which are highly complex and heterogeneous. Current data quality assessment (DQA) standards are siloed and focus on structural evaluations of data quality that provide little or no information about data fitness for an intended use. Objective: The research presented in this dissertation aims to codify and apply a DQA framework that is flexible, reproducible, and can be applied to assess fitness for use in large clinical datasets. Methods: Qualitative methods were utilized to identify important features for a DQA framework as well as to elucidate barriers in implementation. Methods included literature review, content and gap analysis of current practice, semi-structured interviews, and an expert review panel to iterate versions of the framework. The framework connects theoretical constructs, specific check types, and quantitative methods for consistent results interpretation. In order to evaluate the framework following its development, test cases were applied to real world study designs. All output were evaluated for data quality utility and reproducibility. Results: A framework was produced that incorporates the following strategies: (1) standardization and reproducibility of checks; (2) specificity of check terms with paired methods and output; (3) user-driven check specification; (4) accessible methods for both exploratory visualizations and outlier detection; (5) data quality utility that address bias or confounding in studies. To create interpretable results, a variety of quantitative analyses such as summary statistics, median absolute deviation, time series analyses, and inferential tests were selected, as well as visualizations such as bar graphs, run charts, treemaps, heat maps, and dot plots. The DQA modules selected for evaluation addressed different aspects of completeness of patient cohorts: (1) patient fact density; (2) medical complexity representation in cohort; (3) impacts of alternative eligibility definitions. All three identified anomalies in real world data that could introduce significant bias into the study, and that may have been otherwise undetected or unaddressed. Discussion: The results suggest that a fitness-for-use DQA framework is feasible for adoption and application across a range of studies. The features of the framework include both user input and an algorithmic backend that pairs broad data quality concepts (e.g., completeness) with guided specifications, analytic methods, and helpful visualizations. Application of the framework suggests that tools can be developed in the future to aid in reusability across a wide range of clinical studies.
Multi-Physics Finite Element Simulations on Structural Battery Composites
Authors:   , Speck Timothy Joseph , Najafi Ahmad Raeisi
Published: January 2024

Structural Battery Composites (SBCs) are a new type of multifunctional material that provide energy storage and electric power while simultaneously contributing structural integrity. It is essential to characterize SBCs in order to mature the technology for application. In this thesis, a multi-physics SBC negative half-cell is modeled in COMSOL Multiphysics based upon previously developed SBC modeling frameworks. A parametric study is conducted to investigate the effect of design parameters on mechanical performance of the SBC. The SBC model in this study couples thermal, electrochemical, and mechanical effects and considers three basic case studies: tensile, shear, and bending. Within each of the case studies, five parameters are investigated: fiber radius, fiber packing arrangement, fiber type, fiber spacing, and fiber volume fraction. The results show that fiber packing arrangement, fiber type, and volume fraction had the greatest impact to mechanical performance. Additionally, it was observed that different loading scenarios change the sensitivity of the design parameters. The SBC was found to be sensitive to fiber spacing under tensile loading while the design was found to be relatively insensitive to this parameter under shear and bending loading scenarios. Lastly, it the fiber volume fraction was found to have the most considerable effect on electrochemical performance; a lower fiber volume fraction yielded an SBC with a shorter discharge time and a larger fiber volume fraction yielded a longer discharge time. While significant advances in manufacturing technology are required to control the fiber packing arrangement within a composite material, fiber volume fraction remains the most controllable parameter in the state of the art in composite material manufacturing.
Unveiling the Most Delicious Foods in the World by Artificial Intelligence and Google Trends
Authors: Masruroh Betty , Wibawa Aji Prasetya , Harianti Lisa Ramadhani , Djoumoi Ahmed , Maysa Fuad , Ningrum Vira Setia , Rokhman Nissa Mawarda , Anugrah Prananda
Published: January 2024

Food holds significant importance in human existence, serving as the source of energy, as well as the cultural expression, media, and identity of a nation. Currently, gastronomy, or the art of cooking, has gained greater popularity, fueled by an awareness of the importance of healthy and delicious food, along with easy access to culinary information from around the world. Following this popularity, questions concerning the most tasty meal arise, but the answer is subjective in nature. Therefore, this study adopts a novel approach that combines artificial intelligence (AI), consisting of ChatGPT, Bard, and Google Trends, to identify the best global cuisine. The garnered data from Chat GPT and Bard were further analyzed qualitatively, while a quantitative approach was performed on data from Google Trends showing the most popular cuisine globally. The results indicated the five most delicious foods in the world based on Google Trends data, including pasta, sushi, ramen, tacos, and curry. These results differ from ChatGPT and Bard's preferences, where sushi topped the list. The results provide objective guidance for food lovers and the culinary industry and demonstrate the potential of combining qualitative and quantitative approaches in culinary research.