bluuebunny/crossref_metadata_2025 huggingface dataset:
Endovasküler Akut İskemik İnme Tedavisi: İlk 100 Vakanın Analizi
Authors: KOCATÜRK Özcan , KOCATÜRK Mehtap
Published: April 2021

Amaç: İnme, Türkiye’de tüm ölümlerin %15 nedenidir. Akut iskemik inmede(Aİİ) tıkanın damarın açılmadığı her dakikada nöron harabiyeti devam etmektedir ve bugün için Aİİ’nin erken dönem en önemli tedavisi tıkalı damarın hızlı ve etkili şekilde açılmasıdır. Biz bu çalışmada merkezimizdeki inme hastalarına uygulanan endovasküler tedavi deneyimlerimizi paylaşmayı amaçladık.

Materyal ve method: Ocak 2015 ve Kasım 2018 arasında başvuran, Aİİ tanısı konarak endovasküler tedavi alan ardışık ilk 100 hastanın klinik ve demografik özelliklerini ve endovasküler işlem özelliklerini kaydettik.

Bulgular: Çalışmaya dahil edilen 100 hastanın 49’u kadın, 51’i erkekti ve yaş ortalamaları 65(55-74) idi. Hastaların %74’ünde hipertansiyon, %25’inde hiperlipidemi, %38’inde diabetes mellitus, %26’sınde atrial fibrilasyon, %36’ünde koroner arter hastalığı ve %39’ünde sigara kullanımı mevcuttu. Hastaların tedavi öncesi National Institutes of Health Stroke Scale (NIHSS) skoru 15,5 (13-19) idi. Üç aylık takipte 31 hasta kaybedildi ve mortalite oranı %31 olarak hesaplandı. Üçüncü ay sonunda %40 hastada iyi sonuç gözlemlendi (modifiye Rankin skalası skoru 0-2). Etkili rekanalizasyon oranımızın [ Thrombolysis in Cerebral Infarction (TICI2b-3)] %75 olduğu görüldü.
Sonuç: Büyük arter tıkanıklığı düşünülen hastaların en erken dönemde endovasküler tedavi imkanlarının olduğu merkezlere sevki sağlanmalıdır. Merkezlerde endovasküler tedavi deneyimi artıkça daha iyi sonuçlar elde edilebilir.
Türkiye’de Dört Büyük İlde Kamu Hastaneleri Tıbbi Laboratuvar Verilerinin Durumu
Authors: ÇAĞLAYAN Murat
Published: April 2021

Amaç: Çalışmanın amacı, Sağlık Bakanlığına bağlı kamu hastanelerine ait laboratuvar test sayılarının, test puanlarının ve gelir, giderlerinin tüm hastane harcamaları ve bu verilerin yıllara göre nasıl değiştiğinin araştırılmasıdır.Materyal ve Metod: Çalışmaya Türkiye’de 2013-2017 yıllarına ait dört büyük ildeki kamu hastanelerine ait laboratuvar verileri dahil edildi. Çalışmada kullanılan toplam laboratuvar gideri, laboratuvar hizmet gideri, laboratuvar malzeme gideri ve laboratuvar geliri verileri Tekdüzen Muhasebe Sisteminden (TDMS), poliklinik (acil polikliniği dahil) sayıları, yatan hasta sayıları ile ameliyat sayıları Temel Sağlık İstatistikleri Modülü (TSİM) verilerinden elde edilmiştir. 2013-2017 yıllarına göre değişim oranları, toplam gelir ve net hizmet tahakkuk geliri içindeki laboratuvar giderlerinin oranları ve hizmet rolü ortalamaları hesaplanmıştır. Laboratuvar tetkik sayıları, sağlık tesislerinden Sağlık Uygulama Tebliği (SUT) kodu esas alınarak elde edilmiştir.Bulgular: Tüm illerde laboratuvar hizmet alım gideri, laboratuvar malzemesi tüketimi gideri, laboratuvar gideri (hizmet+malzeme) ve toplam gider, toplam net hizmet geliri 2013 yılından 2017 yılına doğru yıllar içinde artmakla beraber, laboratuvar geliri 2014-2015 yılları arası Ankara’da düşüş göstermiş bunun dışında aynı şekilde artış göstermiştir. Laboratuvar gelirinin laboratuvar giderini karşılama oranı İstanbul’da ve Ankara’da her yıl 1’in üzerinde seyretmiştir. İzmir ve Adana’da ise 1’in altında değerler saptanmış, İzmir’de 2016’da, Adana’da ise 2015’ten itibaren laboratuvar gelirleri gideri karşılamamıştır. Laboratuvar tetkik sayılarında tüm illerde sürekli artış saptanmış, yıllar içinde sürekli artış eğilimi göstermiştir. Test sayılarındaki artışın ameliyat sayılarına göre tüm yıllar ve tüm illerde Ankara 2016 yılı hariç daha yüksek olduğu gözlemlenmiştir. Poliklinik sayılarına oranla test sayılarının artışına bakıldığında test sayılarındaki artış oranının ortalama olarak 2015 yılı hariç tüm illerde daha yüksek olduğu saptanmıştır.Sonuç: Laboratuvar giderlerinin toplam hastane giderlerinin yaklaşık %5’ine karşılık geldiğini ve bunun da dünyadaki oranlarla uyumlu olduğunu, laboratuvar test sayılarında yıllar içinde bir artış olduğunu ve laboratuvar test artışında puan bazlı artışın daha fazla olup bu durum daha yüksek puanlı testlerin yıllar içinde daha fazla kullanılmaya başlandığını göstermektedir.
Retrospective Analysis of Patients with Isolated Hand Injuries Admitted to the Emergency Department
Authors: ÇAĞLAR Ahmet , KAÇER İlker , ERYAZĞAN Mehmet
Published: April 2021

Background: Hand and wrist injuries account for approximately 10% of all emergency department admissions. It has been shown that hand trauma, especially hand fractures are associated with social deprivation except for the very young and old. This study was aimed to evaluate the clinical characteristics, risk factors, and the effect of injury on the life of the patients admitted to the emergency department with an isolated hand injury.
Materials and Methods: The patients who admitted to the emergency department due to an isolated hand injury between 1 November 2019 and 1 November 2020 were included in the study. The multivariate logistic regression analysis was used to determine the risk factors of permanent disability.
Results: 205 patients were included in the study with a mean age of 28.05 ± 10.85 years and 142 (69.3%) of them were male. The vast majority of patients (n = 149, 72.7%) were in the 18-35 years age group. The mechanism of injury was blunt trauma in 131 (63.9%) patients and penetrating trauma in 65 (31.7%) patients. Amputation was observed in 25 (12.2%) patients and 20 (9.8%) patients had a permanent disability. Logistic regression analysis revealed that male sex and penetrating traumas were found to be independent risk factors for permanent disability (p = 0.012 and p < 0.001, respectively).
Conclusions: Evaluation of hand injuries and related factors in our region is important due to lifestyle and working condition differences. In our region, male gender and penetrating injuries are independent risk factors for isolated hand injuries. We think that the measures to be taken to prevent the occurrence of such injuries will decrease the permanent disability and related mental and economic burden.
Uji Aktivitas Ekstrak Daun Pirdot (Sauraia vulcani Korth.) Terhadap Pertumbuhan Candida albicans Secara In Vitro
Authors: Marbun Romauli Anna Teresia
Published: April 2021

(Article History: Received 5 October 2020; Revised 8 October 2020; Accepted 15 October 2020) ABSTRAKJamur Candida albicans merupakan jamur penyebab kandidiasis dan penyebab sariawan, lesi pada kulit, vulvavaginistis, candida pada urin (kandiduria), dan gastrointestinal kandidiasis. Salah satu jenis tanaman yang berkhasiat sebagai obat yaitu pirdot (Sauraia vulcani Korth.) dan bagian yang biasanya digunakan adalah bagian daun. Tujuan penelitian ini adalah untuk mengetahui aktivitas ekstrak daun pirdot terhadap pertumbuhan C. albicans secara in vitro. Penelitian ini merupakan penelitian true experiment dengan rancangan penelitian post-test only control group. Metode yang digunakan adalah difusi agar menggunakan teknik kirby bauer. Penelitian ini menggunakan 4 variasi konsentrasi ekstrak daun pirdot, yaitu 10%, 20%, 40%, dan 80%, kontrol positif (tablet ketokonazol), dan kontrol negatif (Dimethyl Sulfoxide). Data yang diperoleh dianalisa menggunakan statistika secara deskriptif. Hasil penelitian menunjukkan daya hambat mulai dari konsentrasi 10% sebesar 8,96 mm daya hambat tertinggi pada konsentrasi 80% sebesar 18,33 mm. Kesimpulan ekstrak daun pirdot memiliki aktivitas antijamur terhadap C. albicans.Kata kunci: Antijamur; Candida albicans; Metode Difusi; Saurauia vulcani Korth. ABSTRACTCandida albicans is fungus that causes candidiasis and causes thrush, skin lesions, vulvavaginism, candidiuria and gastrointestinal candidiasis. One type of plant that has medicinal properties is pirdot (Sauraia vulcani Korth.) and the part that is usually used is the leaves. The purpose of this study was to determine the activity of pirdot leaf extract on the growth of C. albicans in vitro. This study was a true experiment with a post-test only control group research design. The method used agar diffusion using Kirby Bauer technique. This study used 4 variations concentration namely 10%, 20%, 40%, and 80%, positive control (ketoconazole tablets), and negative control (Dimethyl Sulfoxide). The data obtained were analyzed using descriptive statistical analysis. The results showed that the inhibitory from a concentration of 10% of 8.96 mm, the highest inhibition was at 80% of 18.33 mm. In conclusion, pirdot leaf extract has antifungal activity against C. albicans.Keywords: Antifungal; Candida albicans; Diffusison Method; Saurauia vulcani Korth
Uji Antagonis Pseudomonas flourescens spp. Terhadap Isolat Bakteri Xanthomonas (SL3) dari Daun Padi Bergejala Hawar di Kabupaten Kubu Raya
Authors: Larasaty Suprih , Mukarlina Mukarlina , Kurniatuhadi Rikhsan
Published: April 2021

(Article History: Received 21 October 2020; Revised 5 November 2020; Accepted 11 November 2020) ABSTRAKPenyakit hawar pada tanaman padi disebabkan oleh bakteri anggota genus Xanthomonas. Pengendalian penyakit tanaman dapat menggunakan bakteri sebagai Agen Pengendalian Hayati (APH) yang bersifat antagonis terhadap patogen. Pseudomonas flourescens merupakan APH yang memiliki kemampuan penghambatan terhadap bakteri patogen Xanthomonas. P. flourescens spp yang diisolasi dari rhizosfer berbeda memiliki kemampuan penghambatan yang berbeda. Penelitian ini bertujuan untuk menguji kemampuan daya hambat bakteri P. flourescens spp. yang berasal dari rhizosfer yang berbeda terhadap bakteri Xanthomonas yang diisolasi dari daun padi bergejala hawar di Kabupaten Kubu Raya. Penelitian ini dilakukan pada bulan Mei 2019 bertempat di Jurusan Biologi Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Tanjungpura Pontianak. Pengambilan sampel dilakukan di sentra produksi padi Desa Limbung Kabupaten Kubu Raya. Uji antagonis dilakukan di Laboratorium Mikrobiologi Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Tanjungpura Pontianak menggunakan metode Kirby-bauer. Hasil uji antagonis menunjukkan kedua bakteri P. flourescens spp. mampu menghambat isolat bakteri genus Xanthomonas. Jenis P. flourescens spp (Sgu5) memiliki kemampuan penghambatan terbaik hingga mencapai 8,43 mm.Kata kunci: Agen pengendalian hayati; Penyakit Hawar; Pseudomonas flourescens; Xanthomonas (SL3) ABSTRACTBlight disease in rice plants is caused by bacteria belonging to the genus Xanthomonas. Plant disease control can use the Biological Control Agent (APH) which is antagonistic to pathogens.Pseudomonas flourescens is an APH that has the ability to inhibit the pathogenic bacteria Xanthomonas. Pseudomonas flourescens spp. isolated from different rhizosphere had different inhibitory abilities. This study aims to determine the inhibitory ability of the bacteria Pseudomonas flourescens spp. against bacteria isolated from blight with symptomatic rice in Kubu Raya Regency. The research was conducted in my 2019 at the Biology Department, Faculty of Mathematics and Natural Sciences, Tanjungpura University Pontianak. Sampling was carried out at the rice production center in Limbung Village, Kubu Raya Regency.The antagonist test was carried out at the Microbiology Laboratory of the Faculty of Mathematics and Natural Sciences, Tanjungpura University, Pontianak using the Kirby-bauer method. The antagonist test result showed that both Pseudomonas flourescens spp. able to inhibit bacterial isolates of the genus Xanthomonas. Pseudomonas flourescens spp. (Sgu5) has the best inhibition ability up to 8.43 mm.Keywords: Biological control agent; Blight disease; Pseudomonas flourescens; Xanthomonas (SL3)
Pemanfaatan Teknologi Droplet Digital PCR (ddPCR) dalam Kegiatan Analisis Molekuler Tanaman
Authors: Nugroho Kristianto , Widyajayantie Dwi , Ishthifaiyyah Sayyidah Afridatul , Apriliani Elisa
Published: April 2021

(Article History: Received 23 October 2020; Revised 9 January 2021; Accepted 18 January 2021) ABSTRAKSelama beberapa dekade terakhir, teknik PCR memberikan manfaat yang begitu besar dalam kegiatan penelitian di bidang biologi molekuler. Digital droplet PCR (ddPCR) merupakan salah satu teknologi PCR terbaru yang diklaim memiliki keunggulan dibanding teknik qPCR. Prinsip kerja teknik ini yaitu membagi sampel menjadi molekul-molekul kecil yang dipisahkan oleh emulsi minyak, air, dan senyawa penstabil sehingga membentuk droplets. Teknik ini memiliki kelebihan mampu melakukan kuantifikasi absolut maupun relatif pada DNA dengan konsentrasi sangat rendah, tidak memerlukan kurva standar, serta tidak sensitif terhadap kehadiran senyawa inhibitor. Teknik ini telah diaplikasikan pada kegiatan analisis molekuler tanaman di antaranya kegiatan pengukuran konsentrasi DNA dengan sangat akurat, deteksi kehadiran patogen pada jaringan tanaman, dan estimasi jumlah salinan T-DNA pada proses transformasi genetik.Kata kunci: PCR; droplet digital PCR; DNA; biologi molekuler; alat deteksi ABSTRACTOver the past decades, PCR technique has provided enormous benefits in molecular biology research activities. Digital droplet PCR (ddPCR) is one of the latest PCR technologies that is claimed to have advantages over the qPCR technique. The working principle of this technique is to divide the sample into small molecules, which separated by emulsions of oil, water, and stabilizing compounds to form droplets. This technique has the advantage of being able to perform absolute and relative quantification with very low DNA concentrations, does not require a standard curve, and less sensitive to the presence of inhibitor compounds. This technique has been applied to a number of plant molecular analysis, such as for measuring DNA concentrations very accurately, detecting the presence of pathogens in plant tissue, and estimating the copy number of T-DNA in the genetic transformation process.Keywords: PCR; droplet digital PCR; DNA; molecular biology; diagnostic tool.
Lactococcus garvieae Isolates from Rainbow Trout (Oncorhynchus mykiss, W.) Compared by PLG and SA1B10 PCR Primer Pairs
Authors: Altan Erbülent , Korun Jale
Published: April 2021

The aim of this study was to identify and compare Lactococcus garvieae strains using the PLG primer pair and SA1B10 primer pair. Also, the antibiotic resistance of the strains was investigated in the study. For this aim, commercial trout farms at Kemer, Korkuteli, and Manavgat, Antalya Province, Turkey were visited every month from June to September 2018. Thirty sick fish were sampled in the study. Lethargy, anorexia, darkening of skin color, unilateral or bilateral exophthalmos, opacification and hemorrhages in the eyes of the sick fish, and abdominal dropsy were observed. At necropsy, hemorrhages in the internal organs, splenomegaly, and darkening of the spleen and ascites were present. Seventy-five strains from sick fish samples verified on the basis of the biochemical characterization and PCR studies. The strains showed homogeneity in terms of phenotypic characteristics and all strains were identified as Lactococcus garvieae. The PCR technique was applied to 50 of 75 strains using PLG primer pair. While 47 of 50 strains gave positive results, amplification was not observed in 3 strains. When the PCR technique using SA1B10 primer pair was applied to a total of 25 strains, 3 of which were negative, 22 of which gave positive amplification, and 25 strains gave positive results. Resistance was determined by the disk diffusion method. All seventy-five strains were resistant to ampicillin and all strains were susceptible to bacitracin and tetracycline. It was found that the resistance and susceptibility of the strains showed variation to other antibiotics used in the study.Keywords: Lactococcus garvieae; Rainbow Trout; PCR; Antibiotic
Business Model Themes and Product Market Strategies as Value Drivers in Omni-Channel Retail: A Set of Propositions
Authors: Climent Ricardo Costa , Cakir Gültekin
Published: April 2021

We focus on the analysis of current research in Business Models in the context of e-business, resulting in relevant research gaps and a set of propositions. A bibliographic review has been conducted from which a theoretical framework has been developed. Once the gaps in the literature have been pointed out, a series of research proposals are presented. These should be tested based on data collected from real cases through analysis and interpretation. The applied lens of the theory is Amit and Zotts Business Model framework (2001) and Business Model Themes (BMT) “NICE” (novelty, lock-in, complementarity and efficiency) (2001). Analysis evolves around the explanation and feasibility of Business Model Themes for value creation and value capture in digital business models (current general research gap in the e-business domain). The results show that future directions should investigate different combinations of BMTs which represent research gaps (propositions 1 to 3). Other contexts which were not considered so far in this regard (non-digital business), also represent a research gap (proposition 4). Moreover, further synthesis of the literature resulted in a potential consideration of “product market strategies” (Amit and Zott, 2008) as a new theory to apply and test value creation and capturing in digital business (proposition 5 and 6), also from an evolutionary perspective. We ask how this combination affects the performance of firms who want to move on digital transformation with an omnichannel environment. It is essential in this study how these firms can create new value and how they can keep it. We try to explain how these value drivers could be work across time, even under varying environmental regimes. It would mean an advance in the existing academic framework around the reference literature on the business model. To be able to determine which combinations of BMT and Product Market Strategy (PMS) have not yet been tested would be advantageous for the firms. It could offer the appropriate information to the retail company with traditional BM towards digital BM. Moreover, it will be able to work successfully and to maintain constant along the time.
A Field Programmable Gate Array (FPGA) Based Non-Linear Filters for Gas Turbine Prognostics
Authors: Nayak Jayant Kumar , Prasad Vatsala , Ganguli Ranjan
Published: April 2021

The removal of noise from signals obtained through the health monitoring systems in gas turbines is an important consideration for accurate prognostics.  Several filters have been designed and tested for this purpose, and their performance analysis has been conducted. Linear filters are inefficient in the removal of outliers and noise because they cause smoothening of the sharp features in the signal which can indicate the onset of a fault event. On the other hand, non-linear filters based on image processing methods can provide more precise results for gas turbine health signals. Among others, the weighted recursive median (WRM) filter has been shown to provide greater accuracy due to its weight adaptability depending on the signal type. However, sampling data at high rates is possible which needs hardware implementation of the filter. In this paper, the design, simulation and implementation of WRM filters on the FPGA (Field Programmable Gate Arrays) platforms Vivado Design Suite by Xilinx and Quartus Pro Lite Edition 19.3 has been performed. The architectural detail and performance result with the FPGA filters when subjected to abrupt and gradual fault signal is presented.
A STUDY ON SAFETY AND ADVANTAGE OF EARLY ORAL FEEDING OVER TRADITIONAL LATE ORAL FEEDING AFTER OPEN APPENDICECTOMY
Authors: Antony T.Babu , Thirunavukkarasu S. , Prabhu Gokul , Kumar Madhan , kumar S Kiran
Published: April 2021

Acute appendicitis is a surgical emergency and requires surgical intervention. This is a study among 30 patients in tertiary care centre in south india
to compare the efcacy of early oral feeding compared to traditional late oral feeding. Early oral feeding was found to be superior in all aspects over
tradional oral feeding. Hence this can be promoted in all patients undergoing appendicectomy .
EVALUATION OF INFECTION MARKERS IN THE PATIENTS WITH COVID-19 AT TERTIARY CARE INSTITUTE: A PROSPECTIVE STUDY
Authors: Kumar Santosh , Prasad Priyanka , Sinha Ajay Kumar
Published: April 2021

Objectives: The outbreak of 2019 Novel coronavirus disease (COVID-19) has caused global attention. Due to its rapid spread worldwide,
COVID-19 was declared as a public health emergency by the World Health Organization. Although most patients have mild symptoms and good
prognosis, severe COVID-19 cases may present with acute respiratory distress syndrome (ARDS) and systemic inammation. Thus, it is to
evaluate the disease severity and investigate possible biomarkers so as to make fast and correct clinical decisions.
Methods: This is a single center, prospective study conducted at Nalanda Medical College and Hospital Patna. We enrolled 100 OPD and inhospital patients with COVID- 19 admitted to the Nalanda Medical College and Hoapital and analyzed infection biomarkers in covid patients who
had been tested for ferritin, PCT, CRP, IL-6 and procalcitonin.
Results:Average level of Ferritin in Covid-19 patients is 18746.34 ng/ml whereas in control patients it is around 226.29 ng/ml. Around 97 percent
of patients affected with COVID-19 having Ferritin level very high from the referred range. Average level of D-dimer in Covid patients is 2807.16
ng/ml and in non COVID patients 276.04 ng/ml. All the covid patients have D-dimer level very high than the referred range. Average level of
Procalcitonin in Covid and control patients is 0.93 and 0.53 ng/ml respectively. Around three fourth of covid patients and one third of control
patients have this level higher than the referred range. CRPlevel of COVID patients are very high (on an average 483.48 mg/l) in comparison to non
covid patients (on an average 6.29 mg/l). All the covid patients have IL-6 level much higher than the referred range.
Conclusion: Our ndings suggest that level of Ferritin, D-dimer, PCT, CRP and IL-6 can be used to predict the result of COVID-19 test. They can
help in detection of COVID-19 patients.
A STUDY OF THE OUTCOME OF “LIGAMENT CROISE ANTERIEUR" (ACL) RECONSTRUCTION USING AUTOLOGOUS HAMSTRING GRAFT
Authors: Kumar C Arun , Narayan B Ashwanth , Vijay Gussain Rahul , K Venkatachalam , Balasubramaniam Harshiga
Published: April 2021

ACL injury is a widely recognized injury affecting the Genu-Joint Male to female ratio of “L ” injuries are, igament Croise Anterieur (ACL) as high
as 9 :1 igament Croise Anterieur (ACL) . “L ” reconstruction with Hamstring grafts, is currently one of the most commonly used method nowadays.
This Prospective study of 30 subjects treated by surgicalarthroscopic technique, wherein, Quadrupled Graft of Hamstring was used,for the femoral
xation, an endo-button was used, and for the tibial xation, screw of the interference variety was used. Patients were on routine follow up,for at
least a period of one year. All the subjects were subjected to post-operative AP and LAT X-rays, to ear mark the placement of the tunnel and
positioning of the endo-button in the femoral sector and the interference screw in the tibial sector. Subjects were,upon a follow-up program, at
1,2,3months and there again at the end of 6 months and later on twice in a year. All subjects were evaluated with Tegner and Lysholm Knee Scoring
Scale. The major Goal of “L ” recon, is towards re-establishing the stability of the knee. Succe igament Croise Anterieur (ACL) ssful functional
outcomes following “L ” reconstruction,with a Semi-tendinosus Gracilis Graft, ha igament Croise Anterieur (ACL) s been reported in the literature.
The optimal xation methodology for “L ” reconstruction is still evolving and the e igament Croise Anterieur (ACL) xisting xation devices which
has been extensively used are the Endo-button and the “Biological Interference Screws, which has led to a better rehabilitation program postoperatively. In our study, all subjects were ordained to a proper rehabilitation protocol. 10% (n=3) subjects in the present study, had excellent
results, 80% (n=24) of the subjects had good results and 10% (n=3) of the subjects had fair results. No subjects were reported to be, in the poor
outcome category. Treatment of “L ” njuries necessitates, cautious pre-operati igament Croise Anterieur (ACL) i ve planning, selection of patients,
radiological evaluation, selection of graft thickness, planning of timing of surgery, careful intra-operative care, good technique and post-operative
rehabilitation, including thorough counselling for a good functional outcome.
STUDY OF OUTCOME OF CHRONIC KIDNEY DISEASE IN DIABETIC PATIENTS IN THANJAVUR MEDICAL COLLEGE HOSPITAL
Authors: Akilandeswari S.Hema , Rajkanth K. , Janani S.
Published: April 2021

Background: Diabetes Mellitus is one of the common causes of Chronic Kidney Disease which usually leads to end-stage kidney disease. Thus this study was planned to nd out the outcome of CKD in DM, disease progression, appropriate management and the complications. Methods: A cross sectional study among Diabetes Mellitus patients with Chronic Kidney Disease attending the Department of Nephrology and Department of Medicine in Thanjavur Medical College Hospital during the period of July and August 2018. The duration of study period was 2 months. All patients who attended the outpatient department (OPD) and in-patients departments with Type I and Type II diabetes mellitus associated with chronic kidney disease, on any line of management were included in this study. A total of 101 patients were included. Statistical Package for Social Sciences (SPSS for Windows V20) was used for data analysis. Results: Poor glycemic control, albuminuria, hypertriglyceridemia (greater than 150), increase in LDLlevels (greater than 100), BMI (greater than or equal to 25), poor BP control and a longer duration of diabetes mellitus had a strong positive correlation with decrease in eGFR less than 60 ml/min. Glycemic control, weight reduction and adequate BPcontrol retard the progression of CKD. Conclusion: Albuminuria and decline in eGFR both are independent risk factors for diabetic CKD and are strong predictors of morbidity and mortality from a major vascular event, especially cardiovascular complications and stroke.
COMPARING CSF PARAMETERS BETWEEN CHILDREN DIAGNOSED WITH BACTERIALAND ASEPTIC MENINGITIS
Authors: Kumar Sah Love , Manandhar Subin , Pareek Prince , Shah Sanjay , Garegrat Reema
Published: April 2021

Introduction: Diagnosis of meningitis in children cannot rely on clinical examination. Present study aimed to evaluate the role of CSF
examination in differentiating bacterial from aseptic meningitis in children less than 14 years of age. Methodology: This observational crosssectional study included children aged 1 month to 14 years with a diagnosis of meningitis. Children were classied as bacterial meningitis or
aseptic meningitis. CSF examination was conducted to measure CRP, cell count, neutrophil count, lymphocytes, glucose levels and protein levels.
Statistical comparison was made between children with bacterial meningitis and aseptic meningitis. Results: Children aged less than 2 years had
the highest incidence of meningitis to the extent of 30.6%. CSF examination revealed than CRP was found to be positive in 81.82% of the patients
with bacterial meningitis, while only 3.45% of the patients with aseptic meningitis had a positive CRP (p value < 0.001). It was observed that
median cell count and neutrophil count were signicantly higher among patients with bacterial meningitis as compared to those with aseptic
meningitis. While, median lymphocyte count was signicantly lower in patients with bacterial meningitis as compared to those with aseptic
meningitis (p value < 0.001). Furthermore, we observed that CSF glucose less than 50% of that blood levels was observed in 81.82% of the patients
with bacterial meningitis, which was signicantly higher than those diagnosed with aseptic meningitis (p value < 0.05). Conclusions: CSF CRP
and biochemical parameters like cell count, neutrophils and glucose levels can aid in differentiating bacterial from aseptic meningitis
TO COMPARE THE COMBINED EFFECT OF ORAL SILDENAFIL AND ESTRADIOL VALERATE TO ESTRADIOL VALERATE ALONE IN PATIENTS WITH CLOMIPHENE INDUCED CYCLES IN INFERTILE WOMEN ON ENDOMETRIAL THICKNESS.
Authors: Rani Rekha , Singh Shikha , Sahu Sangita , Garg Ruchika , Urvashi Urvashi , Sharma Vandana
Published: April 2021

Objective- Endometrial thickness <7 mm accepted as a reliable sign of suboptimal implantation potential. Clomiphene citrate (CC) has some
negative effects on the endometrium. We evaluated the effect of concomitant administration of oral sildenal and estradiol valerate on endometrial
thickness
Aim- To compare the combined effect of oral sildenal and estradiol valerate to estradiol valerate alone in patients with clomiphene induced cycles
in infertile women on endometrial thickness.
Material And Method- This randomized study was conducted on infertile women attending infertility OPD in SN Medical College, Agra over a
period of 2 years from January 2019 to December 2020. Infertile patients were randomly divided into two equal groups. In control group, 50
patients were given clomiphene citrate 50 mg daily from D2 to D6 along with estradiol valerate 2 mg thrice daily from 2nd day of the cycle till the
day of trigger of ovulation. In study group, 50 patients were given clomiphene citrate 50 mg daily from D2 to D6 along with estradiol valerate 2mg
12 thrice daily plus oral sildenal citrate 25mg every 8 h from 2nd day of the cycle till the day of hCG trigger.
Results- The results in this study conrm the superiority of using oral sildenal with estradiol for improving endometrial thickness, vascularity and
pregnancy rates.
Conclusion- Addition of oral sildenal citrate to estradiol valerate in ovulation induction cycles has better results in improving endometrial
thickness, endometrial blood ow and pregnancy outcome as compared to estradiol valerate alone in women with anovulatory infertility
CLINICAL SCORING OF DEPRESSION INDUCED ENDOCRINE MODULATION IS A RISK FACTOR FOR LOW BONE MINERAL DENSITY IN EARLY AGE EFFECTS ON RENAL FAILURE IN SENILE AGE GROUP.
Authors: Pahari Priyanka , Ailani Vinita , Ganguli Ritwik
Published: April 2021

Background: Osteoporosis is a multifactorial and slowly emerging global health problem. One out of three women between age group of 50-60
years in India suffers from osteoporosis.Indian women have an early age of onset of osteoporosis as compared to western counterparts.We propose
that depression induces early bone loss in majorly premenopausal women and also young age men primarily via specic endocrine mechanisms
associated poor lifestyle habits contributory effects on renal failure in senile age group.
Aim and Objectives:
Ÿ To nd out a new risk factor of secondary osteoporosis in different age group.
Ÿ To nd the clinical correlation between depression, serum cortisol, vitamin D, hypothyroidism,creatinine, eGFR and BMD in different age
group of both the gender .
Ÿ To determine the relationship of decreased renal function with BMD and fracture risk and the role of depression therein.
Methods: The study group consisted of 210 osteoporotic patient's age range between 30-75years.The state of depression was analyzed by using
Ham D scale. BMD and endocrine parameters was measured by DEXA and chemiluminisence, ELISA. Statistical correlation analyzed by SPSS 22
software. Results: A highly signicant (P <0.00001) correlation was observed between HAM-D score and serum cortisol. The correlation between
HAM-D and BMD was also signicant (P <0.05). No signicant correlation was found between BMD and serum cortisol (P฀ 0.05).The
correlation of serum vitamin D with BMD was far more signicant (P<0.00001) compared to the association with TSH (P<0.0001).The statistical
signicance of creatinine value is far more signicant as compaire to eGFR according to age. A high score of depression associated Summary:
with low vitamin D level or high serum cortisol and TSH level which is a risk factor for low BMD in early stage of men and women to develop
secondary osteoporosis associated with renal dysfunction by altering eGFR value. It can be concluded that Irrespective of the specic causes,
subjects with depression should be considered for screening for bone mineral density and, vice versa, subjects with low BMD should be considered
for screening for depression in early stage of life and supplementation of vitamin D with regular physical activity in early stage of life for prevention
of secondary osteoporosis associated with renal failure in senile stage.
AN UNUSUAL CASE OF LARGE PENILE URETHRAL CALCULUS WITH URETHROCUTANEOUS FISTULA IN AN ELDERLY MAN.
Authors: Patil Santosh , Kundargi Vinay S , S Patil Basavesh , Samal Abhijit
Published: April 2021

Impacted penile urethral calculus complicated with urethrocutaneous stula is a rare condition. Such calculi can form as a result of urethral
strictures, meatal stenosis, urethral diverticulum, and migration of stones from the proximal urinary tract. A 65 year old male presented to our
emergency department with complaints of fever and urinary dribbling since 2-3 weeks and obstructive lower urinary tract symptoms since 6
months. He showed features of sepsis and a palpable bladder on examination. Xray KUB and penile USG was suggestive of a 2x1.5cm distal penile
urethral calculus. In this paper we present our approach to such case.
CODEX: Stochastic Encoding Method to Relax Resistive Crossbar Accelerator Design Requirements
Authors: Amirsoleimani Amirali
Published: April 2021

This paper is submitted to IEEE TCAS2. In this paper, A stochastic input encoding scheme (CODEX) is presented that aims to relax the digital-to-analog converter (ADC) design requirements in memristor crossbar systems.
Movimenti e archivi. Punti fermi e questioni aperte
Authors: Musci Leonardo
Published: April 2021

The contribution reflects on the archives of the movements and on the relationship between the characteristics of the productive moment of the documents, their conservative and descriptive destiny and the role of State supervision.
KAJIAN SINTAKSIS DALAM PENGGUNAAN FRASA DI JEJARING SOSIAL FACEBOOK
Authors: Ifantias Meisawitri Gosita , Isani Kulup Luluk
Published: April 2021

Every human being would socialize with other humans. Humans interact by using a tool called language. Language itself is often inerpreted as arbitrary system sounds symbol, languageis universal, that language has meaning or has intention to nonvey something. Language as a meansof social communication can be illustrated in the social network facebook. The phrase is notpredicative and does not have verb and phrases are groups of words. The phrase can be dividedinto phrases and phrases eksosentrik and endosentrik. The use of the phrase alone is consideredless sufficiet when used to make facebook social media users use the appropriate phrase. Facebookuser community consists of some society levels, the top level society, middle level society andbottom level society. Many Facebook users do not care about it because each of them has a styleand language in their own words. No exception educated people, for example, teachers also use alot of slang phrase because era development factors which one of them is language. This studyused a qualitative approach because the research aimed to explain itself and to describe errors ofphrase using that appear in the facebook social media. This research data was screenshot of thestatus sentences .The data source was facebook. Based on the findings of the data and data analysis,it is found some the use of noun phrase, verb phrase, the adjecive phrase, numeralia phrases andprepositional phrase as its function in facebook. According to Samsuri, There are five kinds ofphrases: (1) noun phrase, (2) verb phrase, (3) the adjective phrase, (4) the numeralia phrase, and(5) prepositional phrase. Thus, it can be concluded that there are some the use of phrase thatappears in the status which is written by facebook users.
KAJIAN MORALITAS DALAM NOVEL TUHAN IJINKAN AKU MENJADI PELACUR KARYA MUHIDIN M DAHLAN
Authors: Izzah Nilatul , Catur Budiyono Sunu
Published: April 2021

The research has target for describing moral value that is first figure and communitymoral there are from novel Tuhan Ijinkan Aku Menjadi Pelacur. Morality is quality ofhuman behavior that shows one's behavior is right or wrong, good or bad. In order to makethis research being analyzed, so the researcher use the theory of Thomas Lickona,whichemphasize in three things, those are to know the value of moral, moral feeling, and moralbehavior. Method for this research is hermenutik method (interpreting text). Data and dataresource are the moral value of God bless Me be Prostitute novel by Muhidin M. Dahlan.Data collection technique is using repeat reading, make notes and data classification. Dataanalysis technique is using interpretation, explanation, description, and make conclusion.Data is divided by subs chapter based on the problem and research purpose. Data thatalready been interpreted then it described in an essay as the result. The conclusion by thisresearch is 1) moral knowledge there is moral awareness, knowing moral value, takeperpective, logical of moral and self knowledge from novel “Tuhan Ijinkan Aku MenjadiPelacur” 2) the attitude of moral is moral feeling, conscience, self regard, empathy, good love, self control, and humble. 3) the action of moral is interest, desire, andfigure habits and community. All of the conclusion has been found in the first figure andcommunity from novel “Tuhan Ijinkan Aku Menjadi Pelacur” novel by Muhidin MDahlan.
PENGGUNAAN DIKSI PADA BERITA ONLINE DETIK.COM
Authors: Wibawani Puspa Pitaloka , Isani Kulup Luluk
Published: April 2021

Language is of vital importance matter in human life. One of language function is to communicate. Along growth and advancement of technology, form of communication alsofollows expand and growing sophisticated. In other hand, can also getting the quickerinformation pass by internet that is from online news. Background this Research overshadows by existence of irrelevancy the usage of diction (word choice) that used by at onlinenews. As for research focus this is about diction (diction choice) at Detik.com online news?.Research Target this is describe the usage of diction (word choice) at Detik.com online news.By using descriptive research approach qualitative, this research takes data of have the shapeof phrase or sentence related to diction (word choice), whereas data source at research this isthe set of Detik.com online news. data collecting technique as used in research this is thedocumentation with steps collect online newses and then read citation from news referred as.At technique of data analysis, process of data of analysis have the shape of accurate dataobtained/got, classifying and coding data, interpret data, and conclude data. Base result ofdata analysis and discussion, can be concluded that existed some inaccurates in the usage ofdiction at Detik.com online news, that is at meaning connotative, synonym, antonym, publicword, special word, and foreign word.
Pengaruh Dukungan Sosial terhadap tingkat Stres dalam Penyusunan Tugas Akhir Skripsi
Authors: Daawi Muhammad Mujib , Nisa Walda Isna
Published: April 2021

Sering kali dalam tahap penulisan skripsi dianggap sebagai fase penuh hambatan yang dapat menimbulkan. Dukungan Sosial menjadi salah satu faktor yang dapat mengurangi tekanan ketika individu mengalami suatu masalah. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh dukungan sosial terhadap tingkat stres dalam penyusunan tugas akhir skripsi. Jumlah subjek penelitian ini sebanyak 40 subjek mahasiswa yang sedang mengerjakan skripsi. Pengambilan data menggunakan skala dan wawancara. Skala Dukungan Sosial dengan reliabilitas (α) = 0,90 dan skala Stres dengan besaran reliabilitas (α) = 0,89.  Hasil analisis menunjukkan bahwa tidak ada pengaruh dukungan sosial terhadap tingkat stres dalam penyusunan skripsi (B=0,19; p>0,05). Hasil wawancara menunjukkan bahwa dukungan sosial dianggap tidak berpengaruh terhadap stres yang dialami mahasiswa dalam mengerjakan skripsi, dikarenakan dukungan sosial yang didapatkan tidak sesuai dengan kebutuhan. Sehingga bagi individu yang akan memberikan bantuan perlu menentukan kebutuhan dan jenis dukungan sosial yang dibutuhkan.
МЕТОДИКА ДИАГНОСТИКИ ДЕЯТЕЛЬНОСТИ ПРЕДПРИЯТИЯ В РАМКАХ СИСТЕМЫ МЕНЕДЖМЕНТА
Authors: Никаева Р.М. , Назирова Т.Т.
Published: April 2021

В статье рассматривается определение методики диагностики внутренней сре-ды и механизма её реализации на пред-приятиях. Кроме этого, в статье прове-дена оценка существующим определени-ям термина «диагностика деятельности предприятий». Особое внимание уделено формализации механизма внутренней диагностики на предприятиях. Детально рассматриваются основные этапы это-го процесса. Подчеркивается необходи-мость использования программы и рабо-чего плана внутренней диагностики на предприятиях. Статья привлекает вни-мание к необходимости организации процесса диагностики. Указаны и сгруп-пированы причины проведения внутрен-ней диагностики на предприятиях.
ПРОБЛЕМНЫЕ ВОПРОСЫ МОТИВАЦИИ НА СОВРЕМЕННЫХ ПРЕДПРИЯТИЯХ
Authors: Никаева Р.М. , Назирова Т.Т.
Published: April 2021

В статье рассматриваются проблемные вопросы мотивации на современных предприятиях. Стоит отметить, что эффективная трудовая деятельность основывается на системе мотивации, в своей основе предполагающей удовле-творение и согласование мотивов, по-требностей, интересов, ценностных установок, целей индивидов, предприя-тий, социальных систем. В РФ на специ-алистов в области мотивационной диа-гностики обращали мало внимания. В ос-новном мотивационная работа своди-лась к собеседованию с потенциальным работником. После этого единственной мотивацией становится заработная плата и наказание за некачественно вы-полненную работу в виде различных штрафных санкций.
ИЗМЕНЕНИЕ СОДЕРЖАНИЯ СОЦИАЛЬНОЙ ПОДДЕРЖКИ ВЕТЕРАНОВ В НОВЫХ ЭКОНОМИЧЕСКИХ УСЛОВИЯХ
Authors: Саидов З.А. , Саралинова Д.С. , Юшаева Р.С-Э.
Published: April 2021

Забота о благополучии ветеранов вы-ступает одной из важных стратегиче-ских задач всех органов власти и обще-ства в целом. Многофакторность значе-ния социальной поддержки ветеранов проецирует свое влияние на все сферы общественной жизни. Условия оптими-зации социальной поддержки ветеранов будут наиболее способствовать обеспе-чению их прав на общественное, не де-кларативное, а реальное, признание их заслуг и «социальную благодарность» государства.
Актуальность настоящего исследо-вания обусловлена современными тен-денциями реформирования социальной сферы, мер социальной поддержки вете-ранов всех категорий в соответствии с вектором объективной необходимости развития современной социальной поли-тики. Учитывая данные факторы, крайне важно исследовать совокупность мер и процесс оказания социальной под-держки ветеранам, определить специ-фику и условия оптимизации обозначен-ного комплекса мер.
НЕФОРМАЛЬНОЕ ЛИДЕРСТВО В ОРГАНИЗАЦИИ, ВЗАИМОДЕЙСТВИЕ ФОРМАЛЬНОГО РУКОВОДИТЕЛЯ И НЕФОРМАЛЬНОГО ЛИДЕРА
Authors: Хагаева А.В. , Бачаев А.А. , Горгиев Р.Т.
Published: April 2021

В данной научной статье авторами рас-смотрено общее понятие неформального лидерства и самого неформального ли-дера в коллективе организации. Основное внимание уделено феномену неформаль-ного лидера и взаимодействию с ним формального руководителя организации. Дано определение термину лидер. Также авторы определили виды организацион-ных структур, на основании которых возникают различные виды неформально-го лидерства и формального руковод-ства. Авторами определены основные причины возникновения феномена нефор-мального лидерства, а также выявлены функции, которые осуществляет нефор-мальный лидер в организации. Также в данной научной статье были определены виды неформального лидерства и два основных его типа. Авторами описано взаимодействие формального руководи-теля и неформального лидера. Описаны основные правила влияния руководителя на неформального лидера для его воз-можной нейтрализации, а также сделан вывод о необходимости решения руко-водством проблем, вызвавших появление неформального лидера, а не устранения самого лидера.
ВЛИЯНИЕ ТЕХНОЛОГИЧЕСКОЙ РЕВОЛЮЦИИ НА УНИВЕРСАЛЬНЫЕ КОМПЕТЕНЦИИ ЧЕЛОВЕКА
Authors: Юсупова М.Д.
Published: April 2021

Современная поведенческая и технологи-ческая революция отражает влияние кардинальных изменений в поведении че-ловека как экономического агента, от-крывая возможности для создания ки-берфизических систем, широкой роботи-зации, распространения цифровых тех-нологий. Сложность этой проблемы определяется конвергенцией реального и виртуального миров и проникновением цифровых технологий во все сферы жиз-ни человека. Эти тенденции актуализи-ровали исследование новой роли человека и переосмысление его компетентностей. В статье рассмотрено влияние техноло-гической революции на универсальные компетенции человека и характер тру-довых отношений на мировом рынке труда. Сделаны выводы о том, что раз-витие универсальных компетентностей человека является важным аспектом для современной личности независимо от характера трудовых отношений и сферы повседневной жизни. Обоснована необхо-димость овладения универсальными ком-петентностями человека с целью обес-печения его конкурентоспособности. Вы-делен ряд необходимых универсальных компетенций в зависимости от цели, особенностей развития, характера влия-ния и сферы применения.
ОБЩАЯ ХАРАКТЕРИСТИКА СФЕРЫ ОБРАЗОВАНИЯ РОССИЙСКОЙ ФЕДЕРАЦИИ
Authors: Довлетмурзаева М.А.
Published: April 2021

В современных условиях сфера образова-ния, которая выступает в качестве по-ставщика кадров, стала приоритетным направлением государственной политики высокоразвитых стран. Однако поиск соответствующей организационной структуры у учреждений образования, которые смогли бы обеспечить переход от принципа «образование на всю жизнь» к принципу «образование через всю жизнь» – важнейшая проблема XXI века. Вопросы образования чрезвычайно важны, это одно из главных направлений развития государства и вообще разви-тия в мире. Добиться развития техноло-гий будущего невозможно без качествен-ного образования, а Россия должна быть на шаг впереди в этой сфере.
КОНСТИТУЦИОННО-ПРАВОВОЙ СТАТУС УПОЛНОМОЧЕННОГО ПО ПРАВАМ РЕБЕНКА СУБЪЕКТА РФ
Authors: Довлетмурзаева М.А. , Устерханова А.А.
Published: April 2021

В настоящее время результатом разви-тия общества стало повышение значи-мости и ценности прав человека. Первые исследования правозащитной деятельно-сти появились на фоне роста интереса к общественному мнению в конце 80-х – начале 90-х годов прошлого столетия. В последнее время среди правоведов ак-тивно ведутся дискуссии по вопросам злоупотребления права родителем, проживающим совместно с ребенком, а также о проблемах оставления судами неучтенными некоторых факторов при определении места жительства ребен-ка. Актуальность данной тематики подтверждается официальными стати-стическими данными, примерами судеб-ной практики. Необходимо сослаться на декларативный характер правил, за-крепленных в статье 66 Семейного ко-декса Российской Федерации, а также о необходимости их совершенствования ввиду неприменения в судебной практике.
ОБЩАЯ ХАРАКТЕРИСТИКА СТРАТЕГИЧЕСКОГО ПЛАНА
Authors: Магомадова Э.И.
Published: April 2021

В данной статье рассматриваются во-просы стратегического планирования. Основываясь на теоретической и мето-дологической информации, автор провел углубленное исследование вопросов стратегического плана и процесса его реализации. Инфраструктура предпола-гает наличие инвестиционных проектов и привлечение средств для реализации этих проектов. Стратегическое плани-рование – необходимое условие выжива-ния и развития в современных рыночных условиях. Успех компании заключается в умении учитывать максимально воз-можные факторы внешней и внутренней среды при формулировании стратегиче-ских планов. Поэтому необходимо оце-нить все возможности компании, внеш-ней среды, сформулировать четкие и до-стижимые цели, иметь ресурсы для их достижения. С развитием рынка совре-менным предпринимателям необходимо учитывать множество факторов, по-этому сам процесс планирования стано-вится все более сложным. План может быть краткосрочным и долгосрочным. Это также влияет на всю организацию или направление всей организации.