bluuebunny/crossref_metadata_2025 huggingface dataset:
Research Update on the Therapeutic Potential of Garden Cress (Lepidium
sativum Linn.) with Threatened Status
Authors: Gupta Suchita , Gupta Reena
Published: November 2023

:

Garden cress (Lepidium sativum) has been used in India for medicinal purposes since
the Vedic era. Garden cress, a native of Egypt and southwest Asia, is a small perennial edible
herb that has been used to treat many diseases for centuries. The seeds, leaves as well as roots
have medicinal properties. The seeds are rich in protein, fat, calcium, and iron and have high
nutritional value. They are considered to be galactagogue, anticarcinogenic, antidiabetic, antiasthmatic
and antidiarrheal. Leaves, seeds, and aerial parts extracts are found to have alkaloids,
flavonoids, glycosides, polypeptides, vitamins, minerals, proteins, fats, and carbohydrates.
Lepidium sativum is known for its pungent odor due to the several volatile oils and has been
used to treat various conditions, including respiratory disorders, muscle pain, inflammation, and
bone fractures in the past. Lepidium sativum is a fast-growing annual herb; in India, it is commonly
known as Chandrasoor. Whole fruits or seeds are used, fresh or dried, as a seasoning
with a peppery flavor. Boiled seeds are consumed in drinks by Arabs, either ground in honey or
as an infusion in hot milk. The seed oil can be used for illumination and soap making. Additionally,
limited awareness and conservation efforts have further contributed to its threatened
status. Recognizing the importance of preserving this valuable plant species is crucial for maintaining
biodiversity and ensuring its availability for future generations. Furthermore, this review
explores the potential benefits of Lepidium sativum in different domains. Its nutritional value
and health benefits make it a promising candidate for addressing malnutrition and improving
overall well-being. The presence of bioactive compounds suggests its potential use in functional
foods, pharmaceuticals, and natural medicines for various ailments. Moreover, Lepidium sativum
exhibits antimicrobial and insecticidal properties, offering potential applications in agriculture
and pest control. The current review discussed the nutritional, potential benefits and
pharmacological effects of Lepidium sativum.
Pandemic Preparedness for COVID-19: Research, Healthcare, and
Pharmaceutical Perspectives
Authors: Mani Israel , Nandakumar Manikandan Bilal , Balakrishnan Amara Balan , Rahamathulla Mohamudha Parveen , Pandi Mohan
Published: November 2023

The COVID-19 pandemic has highlighted the critical importance of pandemic preparedness
worldwide, following the devastating 1918 pandemic. The rapid spread of COVID-19, originating
in China, led to its classification as a global pandemic by the World Health Organization.
COVID-19 is a member of the Coronaviridae family, a large family of viruses that have undergone
extensive mutation and evolution over time. Among the coronaviruses, SARS-CoV-2, a Betacoronavirus,
has emerged as a highly virulent pathogen capable of causing severe illness and fatalities
in both humans and animals. Since 1966, various types of coronaviruses have surfaced, each
exhibiting distinct mutations and structural characteristics. These genetic changes have contributed to
the enhanced potency of the virus, intensifying the global pandemic crisis we face today. In response,
the pharmaceutical approach to combat COVID-19 encompasses a multifaceted strategy. This includes
the development of novel antiviral drugs specifically targeting the virus, as well as the repurposing
of existing medications to evaluate their effectiveness against the virus. Additionally, there is
a growing interest in exploring the potential of herbal and traditional medicine in the treatment of
COVID-19. Continued research and collaboration among scientists, healthcare professionals, and
pharmaceutical companies are crucial in the quest to find effective treatments for COVID-19 and to
mitigate the impact of future coronavirus outbreaks. It is imperative to recognize the power and
adaptability of microorganisms, emphasizing the need for vigilance and caution in preventing and
managing infectious diseases. By investing in robust pandemic preparedness, measures and fostering
global cooperation, we can enhance our ability to respond effectively to emerging viral threats and
safeguard public health.
Review of Andrew Hobbs, ed., The Diaries of Anthony Hewitson, Provincial Journalist, Volume 1: 1865–1887 (2022)
Authors: Jones Caroline
Published: November 2023

Review of Andrew Hobbs, ed., The Diaries of Anthony Hewitson, Provincial Journalist, Volume 1: 1865–1887 (2022)
Co-Design of a Virtual Reality Multiplayer Adventure Game for Adolescents With Autism Spectrum Disorder: Mixed Methods Study
Authors: Gabrielli Silvia , Cristofolini Melanie , Dianti Marco , Alvari Gianpaolo , Vallefuoco Ersilia , Bentenuto Arianna , Venuti Paola , Mayora Ibarra Oscar , Salvadori Elio
Published: November 2023

Background

Virtual reality (VR) adventure games can offer ideal technological solutions for training social skills in adolescents with autism spectrum disorder (ASD), leveraging their support for multisensory and multiplayer interactions over distance, which may lower barriers to training access and increase user motivation. However, the design of VR-based game environments for social skills training is still understudied and deserves the deployment of an inclusive design approach to ensure its acceptability by target users.

Objective

We aimed to present the inclusive design process that we had followed to develop the Zentastic VR adventure game to foster social skills training in adolescents with ASD and to investigate its feasibility as a training environment for adolescents.

Methods

The VR game supports multiplayer training sessions involving small groups of adolescents and their therapists, who act as facilitators. Adolescents with ASD and their therapists were involved in the design and in an explorative acceptability study of an initial prototype of the gaming environment, as well as in a later feasibility multisession evaluation of the VR game final release.

Results

The feasibility study demonstrated good acceptability of the VR game by adolescents and an enhancement of their social skills from baseline to posttraining.

Conclusions

The findings provide preliminary evidence of the benefits that VR-based games can bring to the training of adolescents with ASD and, potentially, other neurodevelopmental disorders.
A Web-Based Mindfulness-Based Cognitive Therapy for Couples Dealing With Chronic Cancer-Related Fatigue: Protocol for a Single-Arm Pilot Trial (Preprint)
Authors: Müller Fabiola , van Dongen Sophie , van Woezik Rosalie , Tibosch Marijke , Tuinman Marrit A , Schellekens Melanie P J , Laurenceau Jean-Philippe , van der Lee Marije , Hagedoorn Mariët
Published: November 2023

BACKGROUND

Chronic fatigue is a common symptom among patients who have been treated for cancer. Current psychosocial interventions typically target the patient alone, despite growing evidence suggesting that a couples’ approach can increase and broaden the efficacy of an intervention. Therefore, based on an existing web-based mindfulness-based cognitive therapy for patients, the couple intervention COMPANION was developed.

OBJECTIVE

The primary objectives of this study are to determine the acceptability of COMPANION and its potential efficacy in reducing fatigue in patients with cancer. Our secondary objectives are to examine the feasibility of the trial procedures and the potential working mechanisms of the couple intervention.

METHODS

We will conduct a single-arm pilot trial for couples (ie, patients with cancer with chronic fatigue and their partners). All couples are allocated to the web-based couple intervention that consists of psychoeducation, mindfulness, and cognitive-behavioral exercises. The 9 sessions of the intervention are supervised remotely by a trained therapist. Patients and partners will complete questionnaires before starting the intervention (T0), 2 weeks after completing the intervention (T1), and 1 month after T1 (T2). They will also fill out weekly diaries during the intervention period. A subsample of patients (n≈5) and partners (n≈5) as well as all the therapists providing COMPANION will participate in the final focus groups. Benchmark values have been defined to determine the acceptability (ie, ≥60% of couples complete the intervention and/or ≥70% of the participants are satisfied with the intervention) and potential efficacy (ie, a significant improvement in fatigue and/or a clinically relevant improvement in fatigue in 45% of the patients between T0 and T1) of the intervention. The trial procedures are deemed feasible if an average of at least three couples are included per recruiting month and/or adherence to the assessments is at least 65% for T1 and the diaries and 60% for T2. To establish potential working mechanisms, changes in affect, sleep, catastrophizing, partner communication and interactions, self-efficacy, mindfulness, and closeness will be examined. Quantitative outcomes will be interpreted along with the results from the focus groups.

RESULTS

Data collection is expected to be completed by March 2024.

CONCLUSIONS

This pilot trial will test the first web-based mindfulness-based cognitive therapy for couples targeting chronic cancer-related fatigue. Findings will indicate whether proceeding with a randomized controlled trial is warranted.

CLINICALTRIAL

ClinicalTrials.gov NCT05636696; https://clinicaltrials.gov/study/NCT05636696

INTERNATIONAL REGISTERED REPORT

DERR1-10.2196/48329
Оцінка функціональних результатів, стану сітківки й зорового нерва після вітреоретинальних втручань із застосуванням газової тампонади у хворих на проліферативну діабетичну ретинопатію
Authors: Putienko O.O. , Panchenko Y.O. , Mogilevskyy S.Y.
Published: November 2023

Актуальність. Метою дослідження було провести оцінку функціональних результатів стану сітківки й зорового нерва після вітреоретинальних втручань із застосуванням тільки газової тампонади у хворих на проліферативну діабетичну ретинопатію (ПДР) з різними стадіями проліферативного процесу. Матеріали та методи. Під спостереженням перебувало 48 хворих (48 очей) на ПДР з повною прозорістю вітреального вмісту через 2 місяці після операції. Показанням до вітректомії на 26 очах (54,2 %) був гемофтальм, екстрамакулярна епіретинальна мембрана (ЕРМ) без тракційного відшарування макули — I група. II група — 18 очей (37,5 %) з ЕРМ і тракційним відшаруванням макули і 4 ока (8,3 %) — з тракційно-регматогенним відшаруванням сітківки. Вітректомію виконували калібром 25 G за стандартною схемою. Результати. У пацієнтів, у яких до операції макула була прилеглою, гострота зору покращується в 92,3 % випадків, у випадках з тракційним відшаруванням макули — в 72,7 %. Товщина сітківки після вітректомії у хворих, у яких до операції макула була прилеглою, становить у середньому 206,0 ± 16,8 (без ознак макулярного набряку), стоншення шару нервових волокон в 1 секторі має місце в 16,6 % випадків. У пацієнтів із тракційним відшаруванням макули товщина сітківки в макулярній зоні після вітректомії становить у середньому 291,0 ± 108,7 (у 15 % випадків має місце макулярний набряк), стоншення шару нервових волокон спостерігається в 75 % випадків, переважно в 1 секторі (60 % випадків). Гострота зору значущо нижче при стоншенні шару нервових волокон одночасно верхнього і нижнього секторів (коефіцієнт кореляції R = 0,682; р = 0,031) і при стоншенні шару волокон у трьох секторах і більше (R = 0,713; р = 0,028). Висновки. Виконання вітректомії в ранньому терміні (з макулою, яка до операції була прилеглою) є головним чинником збереження високої функціональної активності сітківки й зорового нерва зі збереженням високих зорових функцій.
Comparative Safety of Antidepressants in Adults with CKD
Authors: Zhu Nanbo , Xu Hong , Lagerberg Tyra , Johnell Kristina , Carrero Juan Jesús , Chang Zheng
Published: November 2023

Background

Depression is prevalent in patients with CKD and is related to poor prognosis. Despite the widespread use of antidepressants in the CKD population, their safety remains unclear.

Methods

We identified adults with CKD stages G3–5 (eGFR <60 ml/min per 1.73 m2 not treated with dialysis) and incident depression diagnosis during 2007–2019 from the Stockholm Creatinine Measurements project. Using the target trial emulation framework, we compared the following treatment strategies: (1) initiating versus not initiating antidepressants, (2) initiating mirtazapine versus selective serotonin reuptake inhibitors (SSRIs), and (3) initiating SSRIs with a lower dose versus a standard dose.

Results

Of 7798 eligible individuals, 5743 (74%) initiated antidepressant treatment. Compared with noninitiation, initiation of antidepressants was associated with higher hazards of short-term outcomes, including hip fracture (hazard ratio [HR], 1.23; 95% confidence interval [CI], 0.88 to 1.74) and upper gastrointestinal bleeding (HR, 1.38; 95% CI, 0.82 to 2.31), although not statistically significant. Initiation of antidepressants was not associated with long-term outcomes, including all-cause mortality, major adverse cardiovascular event, CKD progression, and suicidal behavior. Compared with SSRIs, initiation of mirtazapine was associated with a lower hazard of upper gastrointestinal bleeding (HR, 0.52; 95% CI, 0.29 to 0.96), but a higher hazard of mortality (HR, 1.11; 95% CI, 1.00 to 1.22). Compared with the standard dose, initiation of SSRIs with a lower dose was associated with nonstatistically significantly lower hazards of upper gastrointestinal bleeding (HR, 0.68; 95% CI, 0.35 to 1.34) and CKD progression (HR, 0.80; 95% CI, 0.63 to 1.02), but a higher hazard of cardiac arrest (HR, 2.34; 95% CI, 1.02 to 5.40).

Conclusions

Antidepressant treatment was associated with short-term adverse outcomes but not long-term outcomes in people with CKD and depression.
Strategies to Guide Preemptive Waitlisting and Equity in Waittime Accrual by Race/Ethnicity
Authors: Ku Elaine , Copeland Timothy , Chen Ling-Xin , Weir Matthew R. , McCulloch Charles E. , Johansen Kirsten L. , Goussous Naeem , Savant Jonathan D. , Lopez Isabelle , Amaral Sandra
Published: November 2023

Background

Use of eGFR to determine preemptive waitlisting eligibility may contribute to racial/ethnic disparities in access to waitlisting, which can only occur when the eGFR falls to ≤20 ml/min per 1.73 m2. Use of an alternative risk-based strategy for waitlisting may reduce these inequities (e.g., a kidney failure risk equation [KFRE] estimated 2-year risk of kidney failure) rather than the standard eGFR threshold for determining waitlist eligibility. Our objective was to model the amount of preemptive waittime that could be accrued by race and ethnicity, applying two different strategies to determine waitlist eligibility.

Methods

Using electronic health record data, linear mixed models were used to compare racial/ethnic differences in preemptive waittime that could be accrued using two strategies: estimating the time between an eGFR ≤20 and 5 ml/min per 1.73 m2 versus time between a 25% 2-year predicted risk of kidney failure (using the KFRE, which incorporates age, sex, albuminuria, and eGFR to provide kidney failure risk estimation) and eGFR of 5 ml/min per 1.73 m2.

Results

Among 1290 adults with CKD stages 4–5, using the Chronic Kidney Disease Epidemiology Collaboration equation yielded shorter preemptive waittime between an eGFR of 20 and 5 ml/min per 1.73 m2 in Black (−6.8 months; 95% confidence interval [CI], −11.7 to −1.9), Hispanic (−10.2 months; −15.3 to −5.1), and Asian/Pacific Islander (−10.3 months; 95% CI, −15.3 to −5.4) patients compared with non-Hispanic White patients. Use of a KFRE threshold to determine waittime yielded smaller differences by race and ethnicity than observed when using a single eGFR threshold, with shorter time still noted for Black (−2.5 months; 95% CI, −7.8 to 2.7), Hispanic (−4.8 months; 95% CI, −10.3 to 0.6), and Asian/Pacific Islander (−5.4 months; −10.7 to −0.1) individuals compared with non-Hispanic White individuals, but findings only met statistical significance criteria in Asian/Pacific Islander individuals. When we compared potential waittime availability using a KFRE versus eGFR threshold, use of the KFRE yielded more equity in waittime for Black (P = 0.02), Hispanic (P = 0.002), and Asian/Pacific Islander (P = 0.002) patients.

Conclusions

Use of a risk-based strategy was associated with greater racial equity in waittime accrual compared with use of a standard single eGFR threshold to determine eligibility for preemptive waitlisting.
Unlocking the Innovative and Commercialization Potential of the Undergraduate Final Year ‘Design and Make’ Research Projects
Authors: Svubure Oniward , Pedzisai Constantino
Published: November 2023

Innovation and commercialization are viewed as key drivers of any country’s economy. Individuals normally start commercial enterprises with an innovative and entrepreneurial mindset. Universities worldwide are regarded as centers of knowledge creation and are expected to play a key role in the industrialization of a country’s economy. For undergraduate engineering students, the capstone ‘design and make’ research module is best placed to unlock their innovative and commercialization potential. Capstone modules are typically about applying what the student has learned during the entire course of studies, thereby presenting a rich setting for innovation and entrepreneurial skills learning. In Zimbabwean universities, the final year capstone project is offered where the student fabricates a product as a possible solution to a problem in industry. However, very few of the ideas from the module have found their way into the real world as goods or services. The study’s main question was to establish the extent of the impact of the projects module on agricultural engineering undergraduate students’ innovative and commercial-mindedness. Using the case study research design, data was collected on implementing the capstone module at the Chinhoyi University of Technology’s Department of Agricultural Engineering. Data was collected on the parameters potentially impacting the student’s innovativeness and commercial mindedness. The study findings showed that in its present form, the research project module improves the students’ design and innovative skills. At the same time, equipping the same scholars with entrepreneurial skills is inadequate.
Philippine National Police Women and Children Protection Desk (PNP-WCPD): Strengthening the Intervention
Authors: Naganag Edgar M.
Published: November 2023

The study focused on the Women and Children Desk Tanudan, Kalinga. The research design use was the descriptive design with interview as the main data gathering instrument. The informant were twenty-one victim-survivors whose whereabouts were known. The research found that the PNP Women and Children Desk is implemented as experienced by the victim-survivors. They have received the expected mandatory services, other services provided by the government agency concern and the entitlements. Physical violence is the most frequent crime committed. There were reported incidence of psychological violence such asrepeated verbal abuse, harassment and marital infidelity of the husband. There was no reported incidence of sexual abuse and child abuse. Wife battering dominates the other abuses committed in domestic home. There are psychologically abused women but there were no reports on sexually abused women and child abuse. The important and necessary services and supports to the victim-survivors are provided but not substantial to meet all the needs of the victim. There is no obvious show of convergence among the government concern agencies in response to women abuse. The findings justify the recommendation as follows: More trainings of the PNP Women and Children Desk personnel should be instituted and institutionalized. More Local Government Units involvement should be initiated. A PNP Personnel should be assigned exclusively for the Desk so that the task will be concentrated to manning or managing the Desk.Forge and strengthen the convergence of the government agencies concerned to hasten reporting, communication and delivery of the benefits and privileges of the victims including their immediate and important needs.Finally, institutionalized a massive information-education campaign on the laws concerning the protection of women and their children against abusive and violent partners or parents.
Corporate Social Responsibility Practices Assessment Towards Responsible Entrepreneurship for Tabuk City’s Micro Small and Medium Enterprises
Authors: M. Duyan Karen Razelle
Published: November 2023

This descriptive research aimed to assess analyze and evaluate the implementation of CSR among MSME in Tabuk City All seven indicators indicate mean ratings of ‘great extent’. Among the eleven CSR activities MSME’s are most active in disaster relief assistance activities and are not inclined to support Scientific Researches, Service to Veterans and Senior Citizens, Health Development and Socialized and Low Cost Housing. The extent of implementation of Community research and extension programs of Kalinga State University by its faculty garnered an overall mean of 2.62 which reveals that there is a ‘moderate extent’ of implementation. According to a DTI key person, lack of time, man power, promotion of benefits, incentives and proper coordination are the main problems and challenges encountered by the MSMEs in the implementation of CSR. It is therefore recommended that the College of Business Entrepreneurship and Accountancy should focus more on finding theories and concepts that are appropriate for implementing good and effective CSR by conducting CSR -related researches and the research findings and the theories and concepts formulated should be communicated to the MSMEs through the development of IEC materials and conduct of Training and Seminars. There may be collaborative implementation of CSR programs between Kalinga State University and the MSMEs of which the university may serve as the interceder between the MSME and the community. As an offshoot of the study, a proposed addition to the Research and Extension Agenda of the College of Business Accountancy and Entrepreneurship was crafted and A program proposal that aims to contribute to community development by conducting a series of training/seminars/workshop activities leading to a deeper and meaningful understanding and appreciation of CSR and towards socially responsible MSME’s in Tabuk City Kalinga is formulated.
African Swine Fever (ASF) Outbreak in the Kalinga State University Native Pig R&D Project: The Yookah Depopulation Ordeal
Authors: D. Codiam Sharmaine , S. Ballog Mark Stephen , N. Dongga-as Chester
Published: November 2023

The outbreak of African swine fever in the Yookah Native Pig R&D Project is really a devastating experience, not just wasted financial assistance but most difficult feeling in the part of the researchers who put all their time and effort to produce research results and new knowledge and technology significant in the native pig industry. The objective of the study looked into the factors that caused the outbreak and identified the preventions and controls done during the outbreak. It is found out that human negligence is the number one factor that causes the spread of ASF. But, a good biosecurity protocol and strict implementation of farm rules can somehow prevent and control the spread of the disease in the farm. Based from the results and conclusions of the study, the following is recommended to somehow control and prevent the spread of the disease (1) with or without disease outbreaks, farm biosecurity protocols should be strictly implemented; (2) once confirmed through laboratory test that there is ASF positive in the herd, depopulation of the entire herd is necessary; and (3) if a certain area has still positive cases for ASF, repopulation or acquiring new herd should be avoided. May these ASF outbreak ordeal will serve as a lesson to each and every researcher to be more objective in their approach in conducting researches to avoid uncontrolled situations like this.
Publication Perception of Faculty Researchers in a State University
Authors: M. Duyan Karen Razelle
Published: November 2023

The objective of the study is to create further insights in the level of publication Stress, Attitude and Resources Perception of faculty researchers to find out potential solutions and innovation that would help further research publication in Kalinga State UniversityThis is necessary, as variations in ranks and experience could indicate the necessity for different interventions.The Publication Pressure Questionnaire was used to measure perceived publication pressure inresearchers which consists of three subscales covering Stress, Attitude and Resources. The findings in the study suggest that respondents are optimistic about publishing in their field, and has access to multiple supporting resources as reflected in their subscale scores but perceive their level of performance as overall unsatisfactory. It is revealed thatfaculty researchers who holds higher ranks have lower attitude and resources perception scores but have higher rate in performance. They have equal level of perceived stress attitude and resources across experience but those who have more experience tend to do better in research.To improve the faculty researcher’s performance,the University is recommended to come up with a thorough plan and program interventiontaking into consideration the rank and experience of the faculty researchers to improve their research and publication skills and productivity.
Demonstration Models of Teak and Aonla based Agroforestry in Eastern UP
Authors: Srivastav Anubha , Tomar Anita , Shukla S. D.
Published: November 2023

In view of importance and suitability of Teak and Aonla with different crop combinations, demonstration agroforestry models of these species were developed with the objectives to identify suitable seedling source of Teak and suitable variety of Aonla in different crop combinations for adoption by farmers of Eastern UP. Under model 1 of Aonla based agoforestry, It was found that increment in girth after two year of planting was highest (4.99 cm) for T 6 ( N -7 + agriculture) followed by T8 (chakaiya + agriculture, 4.70 cm) and other varieties with lowest (3.62 cm) value for T1 ( N6 control). On the basis of both height and girth data trends, variety N-7 performed well after two year of planting. Under model 2 in Teak based agroforestry , it was found that increment in girth after two year in T4 (tissue culture + agri) performed well (4.96 cm) after two year of planting followed by other varieties with lowest (3.91 cm) value for T1 . It can be concluded from results of different trials that preliminary trends showed that for Aonla, N7 (Neelam) variety is performing superior compared to other varieties of Aonla with crop combinations of potato, mustard and wheat . In case of Teak, seedlings of tissue culture origin is performing superior as compared to other treatments in crop combinations of gram, burseem and barley . No significant effect of intercropping on trees and crops was experienced in early data of growth parameters of trees and production yield of intercrops.
Enhancing Photovoltaic Solar Panel Efficiency through Integration of Copper and Aluminium Backsheets: A Comprehensive Review
Authors: Kumar Saurav , Agrawal Amit
Published: November 2023

Photovoltaic (PV) solar panels play a pivotal role in the transition to sustainable and renewable energy sources, making it essential to continually improve their efficiency. One promising avenue of research involves integrating materials such as copper and aluminium into the backsheet of solar panels. This comprehensive review article aims to provide a thorough examination of the advancements and potential benefits of incorporating copper and aluminium in PV panel backsheets to enhance their efficiency
To Enhance the Efficiency of PV Solar Panel by Integrating Materials such as Copper or Aluminium behind Solar Panel
Authors: Kumar Saurav , Agrawal Amit
Published: November 2023

Photovoltaic (PV) solar panels play a pivotal role in the global transition to sustainable and clean energy sources. To maximize the potential of solar energy generation, it is imperative to enhance the efficiency of these panels. This study focuses on the integration of materials such as copper and aluminum behind the solar panel, aiming to boost its overall performance. The research presents a novel approach to improving the efficiency of PV solar panels by introducing copper and aluminum backsheets. The incorporation of these metallic materials offers several advantages, including enhanced heat dissipation, reduced electrical losses, and increased mechanical strength. Copper and aluminum's exceptional thermal conductivity helps dissipate excess heat more efficiently, reducing the risk of hotspots and improving overall panel reliability. Additionally, the lower electrical resistivity of these materials minimizes energy losses during the transmission of generated electricity.
ABZYMES: A Comprehensive Review of Applications and Advances
Authors: Chakrabarty Sandipan
Published: November 2023

Abzymes, or antibody enzymes, are antibodies that have enzymatic activity. They can catalyze chemical reactions, similar to traditional enzymes. Abzymes have potential applications in medicine and biotechnology, as they can be engineered to target specific molecules, making them promising for therapies and diagnostics. They often called catmab (from catalytic monoclonal antibody).They can be artificial or naturally occurring, even in autoimmune diseases. They function by stabilizing reaction intermediates, making them valuable tools in biotechnology
Geoprocessamento aplicado ao estudo da dinâmica imobiliária: um estudo de caso sobre vazios urbanos na Região Norte de Niterói/RJ
Authors: Carvalho Rubens Moreira Rodrigues de , Santos Pedro Henrique Pereira Leite dos , Sanfelici Daniel de Mello
Published: November 2023

Estudos recentes mostram aplicações promissoras das geotecnologias no estudo e na gestão da cidade, com subsídios especialmente importantes para a regulação do uso do solo. Neste artigo, tratamos da dinâmica imobiliária e sua relação com o uso do solo com base no estudo de vazios urbanos em áreas infraestruturadas. Esse enfoque atende aos princípios do Desenvolvimento Orientado ao Transporte Sustentável (DOTS), que, dentre outros objetivos, pretende incentivar o melhor aproveitamento do solo urbano no entorno dos sistemas de transportes coletivos. Para analisar o potencial aproveitamento dessas áreas, visando ao cumprimento da função social da propriedade e ao acesso mais justo a serviços e infraestruturas, foi definido um recorte no município de Niterói, no Rio de Janeiro, junto a um importante corredor viário da cidade. Apoiados em diferentes fontes de dados, buscamos identificar nessas áreas tanto os vazios formados por áreas livres como os imóveis edificados considerados ociosos ou subutilizados, no contexto em que se inserem.
ANÁLISE DA PREVALÊNCIA DA COMPRA DE ANTIDEPRESSIVOS NOS MUNICÍPIOS DO VALE DO TAQUARI ASSOCIADOS A UM CONSÓRCIO INTERMUNICIPAL DE SAÚDE
Authors: Graffitti Vanessa , Carvalho Fernandes Luciana
Published: November 2023

Os antidepressivos, medicamentos empregados para o tratamento da depressão, são fármacos que atuam no sistema nervoso central e agem na regulação dos neurotransmissores. Atualmente existem várias classes de antidepressivos disponíveis, o que corrobora na escolha da terapia medicamentosa, são os sintomas apresentados por cada paciente. A aquisição de medicamentos no âmbito público, incluindo os antidepressivos, é realizada através de diferentes modalidades, sendo que, em alguns municípios do Vale do Taquari (VT), a compra é realizada através de Consórcios, os quais fazem a compra de medicamentos aos seus municípios associados. Este trabalho teve por finalidade realizar uma análise da compra dos últimos cinco anos, de medicamentos antidepressivos nos municípios do VT credenciados ao CONSISA. Trata-se de uma pesquisa de caráter quantitativo do tipo documental retrospectivo e a coleta de dados foi realizada através do Banco de Dados da Central de Compras, do Consórcio. Nos anos de 2017 a 2021 a classe farmacológica mais frequente, foi a dos Inibidores Seletivos de Recaptação de Serotonina com 29.202.140 comprimidos distribuídos, seguido pelos Antidepressivos Tricíclicos, com 16.912.170 comprimidos, após os antidepressivos Atípicos com 651.040 comprimidos e por último Inibidores da Recaptação de Serotonina e Noradrenalina, com 463.094 comprimidos. Evidenciou-se que 92% dos municípios que compõe o Vale do Taquari, utilizam o Consórcio para realizar a compra de medicamentos. Quanto a prevalência do consumo, esta aumentou durante o período observado, embora a população tenha permanecido estável.
DOCÊNCIA EM TEMPOS DE PANDEMIA: RELATO DE UMA INTERVENÇÃO PSICOSSOCIAL
Authors: Schwertner Rafaela , Diehl Liciane , Oliveira Michelle Engers Taube de
Published: November 2023

O estudo propõe discutir uma intervenção que ocorreu de forma virtualizada com oito professores do ensino fundamental de uma escola municipal. A proposta foi organizada em torno das temáticas: 1) estressores psicossociais do contexto laboral docente; 2) estratégias de enfrentamento (coping). Verificou-se, por meio dos dados qualitativos, que tal proposta minimizou o sentimento de isolamento e gerou uma rede de suporte social envolvendo empatia, identificação e cooperação para o enfrentamento de situações estressantes.
ATUAÇÃO DO ENFERMEIRO NO CUIDADO AO PACIENTE COM SÍNDROME CORONARIANA AGUDA
Authors: Fonseca Carvalho João Vitor
Published: November 2023

A síndrome coronariana aguda é um evento agudo muito comum nos serviços de emergência no mundo, e que se não atendida prontamente, pode ter desfechos negativos importantes para o paciente, incluindo o óbito. Este estudo buscou por meio de revisão integrativa avaliar os materiais relacionados a enfermagem e a síndrome coronariana aguda nos últimos cinco anos. A pesquisa foi realizada em base de dados eletrônicas na área da saúde. Os descritores utilizados foram: Enfermagem em emergência, Síndrome Coronariana Aguda, Cuidados de Enfermagem. Após busca, análise e seleção, resultaram em 18 artigos. Ao analisar os artigos notou-se que existe um grande déficit em produção de conteúdo relacionado a emergência em enfermagem. Foi observado que o enfermeiro possui funções primordiais no atendimento deste evento, e que a experiência do profissional é um fator determinante na rápida identificação e intervenção de um paciente com evento cardíaco. Foi identificado também que a qualidade do atendimento prestado por ele está intimamente relacionada ao prognóstico do paciente em questão.
ANÁLISE DOS PERFIS SOCIODEMOGRÁFICO E CLÍNICO DOS PACIENTES E PROCEDIMENTOS ESTÉTICOS CORPORAIS EM CLÍNICA ESCOLA DE INSTITUIÇÃO PARTICULAR
Authors: Da Silva Souza Diedja Cleide , Martins Larissa Danielly Araújo , Pereira Junior Adalberto Gomes , Nascimento Iza Neves De Araújo
Published: November 2023

A valorização pela sociedade sobre os recursos estéticos passou a ser relevante, uma vez que houve aumento pela busca de serviços envolvendo a indústria da beleza, o que demonstra uma mudança de comportamento dos indivíduos em relação a sua vaidade e autoestima. Neste sentido, o presente estudo tem como objetivo analisar os perfis sociodemográfico e clínico dos pacientes e os procedimentos estéticos utilizados nos tratamentos no serviço de Fisioterapia Dermatofuncional da Clínica Escola de uma Instituição de Ensino Superior (IES) de João Pessoa. Trata-se de um estudo descritivo, documental, com abordagem quantitativa. A pesquisa foi realizada na Clínica Escola de Fisioterapia do Centro Universitário de João Pessoa– UNIPÊ, localizada na capital paraibana. No período de 2018 a 2019 foram analisados 107 prontuários de pacientes de ambos os sexos. O estudo apresentou um perfil de pacientes mulheres adulto-jovens (93%), residentes em João Pessoa (92,5%), nível de escolaridade entre ensino médio completo e nível superior (77,6%), tendência a hábitos de vida saudáveis, o tempo da queixa foi menor que 5 anos (67%), o número de atendimentos foi menor que cinco para a maioria dos participantes (62%), os problemas mais frequentes foram Lipodistrofia Localizada - LL (36%) e Estrias (33%), em que se utilizou com maior frequência o Ultrassom e a Eletrolipólise para LL e Striart/Striort (97%) para o tratamento das Estrias. Conhecer o perfil dos pacientes, dos materiais e dos insumos mais utilizados facilita o planejamento da instituição quanto à demanda e recursos necessários para os novos serviços prestados ao público.
AVALIAÇÃO DA PERCEPÇÃO DE IMAGEM CORPORAL EM PRATICANTES DE MUSCULAÇÃO DE ACADEMIAS DO VALE DO TAQUARI-RS
Authors: Sulzbach Thalissa , Tiggemann Carlos Leandro
Published: November 2023

A imagem corporal é construída ao longo de toda a vida, sofre interferência de diversos fatores e podendo causar insatisfação do sujeito quanto a sua própria imagem corporal. Perante esse fato, o objetivo do estudo é avaliar a percepção de imagem corporal em praticantes de musculação de academias do Vale do Taquari-RS. Participaram do estudo 158 pessoas, praticantes de musculação há pelo menos três meses, cada sujeito respondeu dois questionários, um para identificar o perfil sociodemográfico e outro para a avaliar a percepção de imagem, por meio do Body Shape Questionnaire (BSQ), que consiste de 34 perguntas. A mostra foi composta majoritariamente por mulheres (68,4%), com sujeitos de idade média de 30,46 ± 10,09 anos, Índice de Massa Corporal (IMC) médio de 24,29 ± 3,75 kg/m2, classificado 65,8% como normal. A média dos scores foi de 79,43± 30,01, sendo que 133 sujeitos (84,2%) não demonstraram insatisfação com a autoimagem corporal, 17 (10,8%) foram classificados como insatisfação corporal leve e 8 (5,1%) tem insatisfação corporal moderada/grave. A pesquisa também mostrou que as mulheres e pessoas mais jovens têm maiores médias na pontuação do score do questionário. Conclui-se que a maior parte dos entrevistados não possui insatisfação com a imagem corporal, porém constata-se um comportamento de que as pessoas mais novas e as que passam mais tempo navegando nas redes sociais possuem scores maiores de insatisfação da autoimagem corporal.
PREVALÊNCIA DE ALERGIAS POR ÁCAROS EM TRABALHADORES DE AVIÁRIOS
Authors: Da Silva Eduarda Damé , Pompermaier Henrique Valério , Laste Gabriela , Lohmann Paula Michele , Johann Liana , Da Silva Guilherme Liberato
Published: November 2023

Ambientes de aviários constituem um amplo espaço de exposição a diversas fontes alergênicas, ainda sendo caracterizado por um espaço de circulação de trabalhadores que estão diariamente expostos a tais fontes. Nesses ambientes convivem os ácaros, uma das principais fontes de alergia ocupacionais e domésticos do mundo. Os efeitos causados em pessoas predispostas acarretam o desenvolvimento de patologias, como a dermatite atópica e as inflamatórias do trato respiratório, asma e rinite alérgica. Este estudo teve como objetivo verificar a prevalência de alergias a ácaros em trabalhadores de uma empresa de aves, através da coleta de sangue para análises clínicas para IgE específica para ácaros. Com o intuito de associar informações dos trabalhadores aos resultados laboratoriais, foi aplicado um questionário adaptado para adultos da International Study of Asthma and Allergies in Childhood – ISAAC, o qual possui perguntas objetivas que buscaram verificar a presença de doenças respiratórias como asma, rinite e eczema. Os resultados evidenciados, mostraram que três dos 15 participantes apresentaram alta hipersensibilidade aos ácaros avaliados, todos do sexo masculino. Além disso, foi verificado que nenhum dos hipersensibilizados apresentou episódio de asma durante a vida. Porém todos reportaram episódios de rinite alérgica, com coriza e espirros, juntamente com coceiras nos olhos, sem estar gripado ou com infecção de vias aéreas superiores. Relacionado à problema com espirros e coriza quando não estavam resfriados, 10 confirmaram o fato, destes, oito tiveram esse relato nos últimos 12 meses, dos oito confirmados nos últimos 12 meses, sete tiveram coriza acompanhado de coceira nos olhos. Os meses que mais prevaleceram essas irritações foram os meses de maio e julho, e apenas dois deles relataram um leve problema para realizar atividades físicas diárias. Quando perguntados sobre já ter sofrido por rinite alérgica, 53% confirmaram já ter tido algum relato. Este trabalho foi de cunho inédito, visto que é o primeiro trabalho que avaliou a prevalência de alergias em trabalhadores de aviários, por meio de testes laboratoriais e estudo por questionários.
REFLEXÕES ACERCA DOS CUIDADOS PALIATIVOS EM PACIENTES COM ALZHEIMER: UMA REVISÃO INTEGRATIVA
Authors: Christian Bárbara Mendes de Ávila , Silva Carlos de Jesus , Jacinto Giassi Júlia Misty de Oliveira , Lima Pablyanne Oliveira , Dos Santos Souza Mariana Cristina
Published: November 2023

Introdução: A doença de Alzheimer consiste na perda em grande quantidade, e de forma contínua, dos neurônios nas regiões cerebrais responsáveis pelas memórias, pensamentos, raciocínio e linguagem. Esta doença não tem cura, mas há tratamento paliativo com o foco de atenuar o desenvolvimento dela, assim, conservando as funções cognitivas e promovendo a melhora no bem-estar do paciente e dos cuidadores. Objetivo: Identificar e sintetizar as pesquisas que versam sobre os cuidados paliativos em pacientes com Alzheimer. Método: Revisão integrativa realizada nas bases de dados BDENF, MEDLINE E LILACS, por meio da Biblioteca Virtual em Saúde (BVS), com a seguinte questão norteadora: “Qual o papel dos cuidados paliativos para pessoas com a doença de Alzheimer (DA)? Resultados: Foram identificados 290 artigos, e após a etapa de triagem e elegibilidade, foram selecionados sete artigos para a composição deste estudo. Os estudos foram divididos em três classes temáticas, para discussão em profundidade: autonomia e dignidade do paciente com Alzheimer, papel dos cuidadores de pacientes com doença de Alzheimer e necessidades e tratamentos dos pacientes com doença de Alzheimer. Conclusão: Os cuidados paliativos podem determinar uma melhora no bem-estar desses pacientes, sendo imprescindível uma assistência completa para reduzir o sofrimento como tratamentos não farmacológicos e a preservação da dignidade e da autonomia do paciente. Além disso, foi perceptível a necessidade de um maior investimento na área para especialização dos cuidadores e de um acompanhamento psicológico para a família e/ou o cuidador responsável por este paciente, pois as demandas de cuidado do enfermo podem ser exaustivas, afetando diretamente nos cuidados prestados.
OCORRÊNCIA E DISTRIBUIÇÃO POTENCIAL DE PYRODERUS SCUTATUS (AVES: COTINGIDAE) NO SUL DO BRASIL
Authors: Da Rosa Cristina Freitas , Corrêa Luiz Liberato Costa , Lopes Sérgio Nunes
Published: November 2023

Estudos preditivos direcionados a aves com necessidade de conservação vem sendo divulgados na literatura especializada, prevendo áreas com adequabilidade ambiental para ocorrência destas espécies. O Pavó (Pyroderus scutatus) é uma ave neotropical de hábitos florestais, endêmica de Mata Atlântica. No estado do Rio Grande do Sul (RS), na região Sul do território brasileiro é considerada ameaçada de extinção. Neste sentido, o presente estudo teve por objetivo atualizar e prever a distribuição potencial do P. scutatus no RS. Através de dados secundários obtidos em literatura, fontes online e informações cedidas por pesquisadores, compilou-se os dados de presença com o uso de variáveis bioclimáticas (de Bio1 a Bio19) e o algoritmo MaxEnt. A taxa de desempenho do modelo foi 0,95, indicando um modelo robusto e variável que apresentou maior contribuição no modelo foi Variação Diurna Média de Temperatura (Bio2). Pyroderus scutatus apresenta ocorrência em 26 municípios do RS entre os biomas Mata Atlântica e Pampa, em áreas sem conservação e proteção ambiental. Este estudo reuniu o conhecimento disponível sobre a distribuição de P. scutatus no RS, indicando áreas com adequabilidade ambiental para a ocorrência essa espécie em nível regional.
Dampak Peran Ganda Petani Perempuan dalam Kehidupan Rumah Tangga di Masa Kini
Authors: Hamdani Thaha  , Yuniar Vera
Published: November 2023

The dual role of women is the active involvement of women in the process of achieving goals based on independent personal abilities in deciding a goal. Women as wives for their husbands and as mothers of children is a status that has consequences for their role in family life, but sometimes that role does not function properly because it is accompanied by other roles as breadwinners, sometimes even that role becomes dominant to women's attention because it is related to family survival. The purpose of this study was to impact the dual role women to work as farmers in Gamaru Hamlet, Ulusalu Village, Latimojong District, Luwu Regency, South Sulawesi. This research is a type of qualitative research with a case study approach. Researchers obtained data through observation, interviews and documentation. The results of this study are four impacts experienced  by women in carrying out their dual roles as farmers in  Gamaru Hamlet, Ulusalu Village, Latimojong District, Luwu Regency, namely first Social Status, second Economic Impact, third Impact on family life, fourth Social Impact. The implications of the research are expected to be able to change people's views that domestic roles are not only women's affairs (wife) but also husband's affairs.
Etika Bermedia: Menyebar Foto dan Video Tanpa Izin Termasuk Melanggar Privasi
Authors: Fitriani Nanda Elma , Syayekti Ela Indah Dwi , Hidayatullah Muhammad Syarif
Published: November 2023

This study aims to determine ethics in media including taking photos or videos that include privacy. Not everyone likes it when their photos appear on social media. This will realize the importance of upholding ethics in media. The method used in this study is library research by collecting information and data with the help of various kinds of existing materials such as documents, books, journals, articles and so on. The results of this study show that media ethics are very important today. The right to privacy is often forgotten by media users, especially when taking pictures or recording others without permission. The rules of social media are in fact not in harmony with conditions on the ground. Many violations occur, for example the distribution of photos and videos of someone without permission to the person concerned. It is expected that users will be wiser in addressing the boundaries needed when mediating. In addition, media providers should provide features that support the security and privacy of their users.
CORAK HERMENEUTIKA AL MAWARDI DALAM KITAB AL-NUKAT WA AL ‘UYŪN
Authors: Anam Syariful
Published: November 2023

The discourse of hermeneutics (interpretation) of the Qur'an becomes an interesting and factual study. Examining one of the monumental works of the Mufassir figures that should be taken into account is Shaykh al Mawardi. He is not only a bureaucrat who served as a Supreme Judge but also a Mufassir who should be used as a reference in ideas and thoughts. Through the work of al-Nukat wa al-'Uyūn, al Mawardi tries to offer a style of interpretation that combines the method of history (Naql) by involving linguistic reviews, grammar and jurisprudence, while the other side al Mawardi also used ijtihadi method (khalaf) by quoting and comparing the opinions of Mufassir. These two double steps are the distinction from other Mufassir, so the author tries to present and disseminate the style of interpretation of al Mawardi. This research is a literature study of the work of tafsir al Mawardi through a review of descriptive analysis of his interpretation method. The findings in the study indicate that al Mawardi has a distinctive method, namely the style of interpretation that tries to accommodate classical and contemporary models of interpretation (Ijtihādi) by citing some opinions of previous Mufassir and Fuqohā'.