bluuebunny/crossref_metadata_2025 huggingface dataset:
The Jurimetri Formulation of Court Decisions in the Division of Joint Property
Authors: Khoirunnisa Khoirunnisa , Hidayati Rahmi
Published: January 2024

This paper analyzes the results of court decisions on the application of jurimetric formulations in the division of joint property as an effort of justice. Jurimetry can be used as an option when the division of joint property regulated in the Compilation of Islamic Law does not guarantee justice to the parties. Jurimetry emphasizes the division of joint property based on the implementation of the obligations and responsibilities of each party while bound by marriage, so that the use of jurimetry will provide a greater sense of justice. The focus of this article is how the jurimetry formulation of court decisions in cases of division of joint property and its relevance to the principles of justice. This article is a literature research with a normative approach. The source of data in writing this article is court decisions regarding joint property. The result is that the application of jurimetry in the division of joint property can provide more justice for the parties. Parties who do not carry out their obligations in full will have their rights to joint property reduced in accordance with their actions. Conversely, parties who carry out their obligations in full will get rights in accordance with their actions. If both parties carry out their obligations in full, then both are entitled to the same amount of joint property. The recommendation of the results of this writing is that the judge can use this jurimetric formulation as a consideration in handling joint property disputes. Keyword: Jurimetry, Joint Property, Justice and Legal Reform
Childcare in Lampung Saibatin Indigenous Community from the Perspective of Mubadalah and its Contribution to the Development of Family Law in Indonesia
Authors: Sutendy Deddy , Isa Rozana
Published: January 2024

This article examines childcare in the Lampung Saibatin indigenous community from the perspective of mubadalah and its contribution to the development of family law in Indonesia. This research is field research or filed research conducted in the Lampung Saibatin indigenous community in Lampung Province, conducting interviews with Lampung Saibatin traditional leaders and Lampung Saibatin indigenous people, analyzed qualitatively using the theory of mubadalah. The results of the study show that the Lampung Saibatin indigenous community has a pattern of childcare carried out by the mother, but as time goes by there are already some parents who have implemented that in childcare is carried out jointly by both parents. The existence of care that is dominated by the mother because the father earns a living for the needs of the family, on the other hand there is a classic paradigm that the wife's job is to take care of the house and children while the husband works. In this digital era, it is expected that childcare is carried out jointly, father and mother proportionally, so that this research contributes to campaigning for balanced parenting or mubadalah between father and mother. At the same time as an effort to educate the Lampung Saibatin community who still have a classic paradigm that emphasizes the dominance of childcare only to the mother, so that they can slowly change the paradigm into childcare that has a more balanced value of mubadalah between the father and mother.Keyword: Childcare; Lampung Saibaitin; Mubadalah
Regulation of the Director General of Islamic Guidance on Marriage of Husband during Wife's Iddah Period: An Effort to Develop Family Law in Indonesia
Authors: Miftahudin M
Published: January 2024

This article examines the marriage of a husband during his wife's iddah period at the Office of Religious Affairs in Lampung Province, and analyzes the practice based on the Circular Letter of the Director General of Islamic Guidance. The purpose of this article is to review the reasons for considering the Circular Letter of the Directorate General of Islamic Guidance towards women's rights, and what relevance the Circular Letter of the Directorate General of Islamic Guidance towards the development of Islamic family law in Indonesia. The method used is qualitative, this type of research is field research, which is conducted at the KUA in Lampung Province, as a sample of Bandar Lampung City, Metro City and East Lampung Regency. Data sources in this research are primary and secondary data sources. Data analysis techniques using inductive framework, analysis using mashlahah theory. The result of the research is that the Circular Letter of the Director General of Islamic Guidance Number P-005/DJ.III/HK.00.7/10/2021 concerning Marriage of Husband in Wife's Iddah Period, is a regulation that regulates the prevention of husbands who want to marry during their wife's iddah period. The existence of this prevention is an effort to create balance between men and women in iddah arrangements, this will have an impact on the value of gender justice and create benefits between couples as an effort to protect the rights of women/wives. The Circular Letter of the Director General of Islamic Guidance on Marriage in the Iddah Period of the Wife should become the status of a law, which can be binding in general and broadly, and has legal force, this is important as the development of Islamic family law in Indonesia.Keywords: Regulation of the Director General of Bimas Islam, Iddah Period, Islamic Family Law
State Attorney Law Enforcement in Marriage Annulment and its Contribution to the Development of Family Law in Indonesia
Authors: Zaharuddin Dicky , Sharmani Mulki
Published: January 2024

This articleexamines the optimization of law enforcement by prosecutors in annulling marriages and its contribution to the development of Islamic family law in Indonesia. This research is library research, analyzed by descriptive analysis, which is done by describing the existing facts, the method of analysis used is qualitative method, using Gustav Redbruch's theory of legal objectives. The result of this study is that the optimization of law enforcement by prosecutors in annulling marriage is relevant to Gustav Redbrudh's theory of purpose, that the purpose of law is to provide justice, legal certainty and legal benefits. With the prosecutor being given regulatory rules that support his role in enforcing the law in the field of marriage annulment for someone who violates the legislation, legal justice, legal certainty and legal benefits will be created in the community. The researcher's contribution to the development of family law in Indonesia is in the form of a proposal to policy holders, so that regulations are legislated that specifically regulate the technical guidelines that prosecutors are allowed to act directly in marriage annulment applications.Keyword: Optimization, Law Enforcement, Prosecutor; Marriage Cancellation
The Effect of Multimedia on L2 Idiom Learning: Using Instructional Humorous Videos with Saudi Female EFL Undergraduate Learners
Authors: Ayedh Saeed Dajem Manal
Published: January 2024

Learning formulaic language, such as idioms, is considered one of the greatest difficulties encountered by EFL learners. The aim of the present study is twofold: first, to examine the effect of using humorous videos on learners’ ability to understand and remember English idioms; second, to investigate students’ attitudes towards learning idioms through humorous videos as a multimedia instructional method. The sample of this study consisted of 50 Saudi female EFL undergraduate learners in the English department at Imam Mohammad Ibn Saud Islamic University, Saudi Arabia. The participants were divided into two groups of 25 students; an experimental group and a control group. The data of the study was collected via three research instruments: pre-test, immediate and delayed post-tests, and an attitudinal questionnaire. A pre-test was given to both groups at the beginning of the study to ensure that they were equivalent. Proceeding this, the experimental group was instructed using humorous videos, while the control group was instructed in the traditional method. Finally, both groups underwent post-tests to measure the performance effects on two levels of idiomatic knowledge: recall and transfer. Results showed that there was a statistically significant difference between the performance of the experimental group and the control group; indicating a positive effect on the experimental group’s recall and transfer. Thus, the study concludes that the use of humorous videos appears to improve learners’ ability to understand and remember English idioms, in addition to indicating that learners hold a positive attitude towards learning idioms through humorous videos as a multimedia instructional method.
Pengaruh Kesadaran Wajib Pajak, Pemeriksaan Pajak Dan Penagihan Pajak Terhadap Penerimaan Pajak Penghasilan Badan Pada Kantor Pelayanan Pajak (KPP) Pratama Metro
Authors: Saketi Via Dewi , Zanaria Yulita , Kurniawan Angga
Published: January 2024

This study aims to analyze Taxpayer Awareness (1), Tax Audit (2), Tax Collection (3) on Corporate Income Tax Receipts at the Tax Service Office (KPP) Pratama Metro. The population in this study were 94 respondents.The data collection technique in this study used a saturated sampling. This method is where all the population is sampled. The data in this study used SPSS version 26 with multiple linear regression analysis testing. The results of this study indicate that Taxpayer Awareness, Tax Audit, Tax Collection have partial or simultaneous effect on Corporate Income Tax Receipts at the Tax Service Office (KPP) Pratama Metro
Analisis Pengendalian Persediaan Barang Dagang (Inventory) Dan Harga Pada Keputusan Pembelian Air Minum Dalam Kemasan (Amdk) Merek Isqo PT Metro Surya Inovasi (PT Mesva) Di Kota Metro Lampung
Authors: Ruswanti Lilis , Nusantoro Jawoto , Kurniawan Angga
Published: January 2024

This research is a qualitative research with a qualitative descriptive method. This study took 1 respondent from the warehousing staff of PT Metro Surya Innovation as a provider of information about the company's merchandise inventory and 6 large outlets selling Isqo brand bottled drinking water as a provider of price information on purchasing decisions for isqo brand bottled drinking water. Data collection techniques using observation, interviews, and documentation. Based on the results of the analysis and assessment in this study, it shows that in the period August-December 2021, the EOQ/KPE method is 999 units/box with a repurchase frequency of 14 times. Safety stock is 95 units/box and ROP/TPK 190 units, the maximum inventory of goods at the company that must be maintained is 1,094 per day. Based on the comparison results if the merchandise control method is carried out using the EOQ/KPE method, the company can increase efficiency and provide benefits to the company with a cost difference of Rp. 7,281,281. The results show that by using the EOQ/KPE method, the company can precisely determine the safety stock so as to minimize the occurrence of shortages of goods and can also determine the ROP/TPK to avoid delays in ordering and delivery of goods to the customer.
Pengaruh Bauran Promosi Terhadap Keputusan Konsumen Dalam Pembelian Mie Instan Merek Sedaap Di Desa Dalu X A Kecamatan Tanjung Morawa
Authors: Anggraini Cut Widya , Lubis Tukimin
Published: January 2024

This study aims to determine the effect of the promotional mix on consumer decisions in purchasing Sedaap brand instant noodles in Dalu X A Village, Tanjung Morawa District. This study uses a type of quantitative research. The population in this study were the people of Dalu X A Village, totaling 250, with 154 respondents taking samples using the slovin formula. The results of this study were collected through a questionnaire which was analyzed using multiple linear regression. The sampling method used in this research is stratified random sampling. The results of this study indicate that X1 is significant by 0.000 <0.05, thus advertising has a positive and significant effect on consumer decisions, sales promotion X2 is significant by 0.000 <0.05, thus sales promotion has a positive and significant effect on consumer decisions, and publicity X3 is significant at 0.000 <0.05, thus publicity has a positive and significant effect on consumer decisions. Fcount is 98.520 > Ftable 2.43 and sig. 0.000 < 0.05. The results of the F test prove that advertising X1, sales promotion X2 and publicity X3 simultaneously have a positive and significant effect on Y's purchasing decisions.
Perbandingan Pemahaman Penyusunan Laporan Keuangan Usaha Kecil Menengah Berdasarkan SAK EMKM
Authors: Siregar Rahmah Sudana , Dalimunthe Ahmad Amin , Hasibuan Nur Fadhilah Ahmad
Published: January 2024

The purpose of this study was to determine the understanding of the preparation of financial reports at Gajah Farhan Bakery and UD. Blessing. This study uses a qualitative method with a descriptive approach. The subjects in this study were the business actors of the Gajah Farhan Bakery and UD. Blessings as well as being the object of this research are the financial records of the two business actors. Based on the results of the study, it was shown that the understanding of the preparation of financial reports at Gajah Farhan Bakery's Earloaf Factory was not good, but at UD. The blessing of the understanding of business actors can be said to be good. The two business actors have made financial records but are not in accordance with SAK EMKM. Equation of financial records for the two business actors has also made financial records in the form of cash-in and cash-out bookkeeping as well as debt receipts, receivables and inventories. And the difference between the financial records of the two business actors lies in UD. It is a blessing that makes financial records of the balance sheet and profit and loss, but for the Elephant Earloaf Factory it does not make financial records of the balance sheet and profit and loss.
Sistem Pembiayaan KPR Sejahtera Fasilitas Liquiditas Pembiayaan Perumahan (FLPP) Dengan Akad Murabahah Bagi Masyarakat Berpenghasilan Rendah (MBR)
Authors: Nurbaeti Siti
Published: January 2024

The study aims to determine the suitability of the Prosperous KPR Financing System Housing Financing Liquidity Facility (FLPP) for Low-Income Communities (MBR) with a Murabahah Agreement at PT. Bank Syariah Indonesia kcp abdullah bin Nuh Abn 1 Cianjur with DSN-MUI/IV/2000 Fatwa. Data collection techniques using Participatory Observation interviews, documentary studies, triangulation, secondary data and primary data. The result of this study indicate that PT. Bank Syariah Indonesia KCP Abdullah bin nuh cianjur does not fully reflect the fatwa form the national sharia council No:04/SN-MUI IV/2000 concering murabaha.The violation occurred in term of ownership of goods (milkiyah) in the third point, namely the bank should buy goods needed by the costumer on behalf of thebank itself, but in practice the bank bus onbehalf pn the costumer and back completes the murabhah contract first to the new customer to enter ito a wakalah contract.
Analisis Penerapan PSAK 109 Dan PSAK 101 Penyajian Pelaporan Keuangan Akuntansi Zakat Dan Infaq/Sedekah Pada Lazismu Kl Ummi Dan Lazismu Kl Aisyiyah
Authors: Al Fianty Amelia , Kartini Tina , Noor Iqbal
Published: January 2024

This research was made to find out how the application of the Sharia Financial Accounting Standards Statement (PSAK) No. 109 and 101 regarding the presentation of the financial reports of LazisMu KL UMMI and LazisMu KL Aisyiyah, as well as knowing the obstacles in compiling the financial reports that have been made. This study used a qualitative research method with a descriptive approach. The variable used in this study is where the social situation in this study consists of three elements, namely places, people and activities. The technique used in data collection is the triangulation technique, which includes observation, interviews and documentation. With data analysis techniques performed include data reduction, data presentation, and drawing conclusions.The results of this study indicate that LazisMu KL UMMI and LazisMu KL Aisyiyah have implemented Zakat, Infak/Shadaqah Accounting in accordance with the Statement of Financial Accounting Standards (PSAK) 109. However, the disclosures are not appropriate, because notes to financial statements have not been made. In addition, the financial reports prepared by LazisMu KL UMMI are in accordance with Statement of Financial Accounting Standards (PSAK) 101, while LazisMu KL Aisyiyah is not yet in accordance with PSAK 101 concerning the presentation of financial reporting.
Pengaruh Penerapan Efektivitas Dan Kepercayaan Atas Sistem Informasi Akuntansi, Pemanfaatan Teknologi Dan Kompensasi Sumber Daya Manusia Terhadap Kinerja Karyawan Bank BRI Lampung Tengah
Authors: Leni Leni , Zanaria Yulita , Kurniawan Angga
Published: January 2024

This study aims to determine the effect of implementating effectiveness and trust in accounting information systems, technology utilization and human resource compensation on employee performance at Bank BRI, Central Lampung. This type of research is quantitative research. The instruments used in this study were questionnaires and observations. The data analysis technique performed is using multiple regression analysis. The results of the study show that the Effectiveness of SIA Implementating has a positive and significant impact on employee performance. SIA trust has a positive and significant influence on employee performance. The use of technology has a positive and significant impact on employee performance. Compensation has a positive and significant impact on employee performance
Analisis Faktor yang Memengaruhi Tingkat Diabetes Melitus pada Masyarakat di Kota/Kabupaten di Provinsi Jawa Timur Tahun 2018
Authors: Azmi Gilang Juniar , Dewi Putri Qoonitah , Anugerah Siti Yuditha Cahaya , Oktarina Sachnaz Desta , Rizki Akbar , Nurhambali Muhammad Rizky
Published: January 2024

Among the non-communicable diseases, diabetes mellitus is one of the most significant contributors to mortality. This condition is a silent killer because its signs are hard to identify, and its prevention efforts are strenuous. Diabetes mellitus cases in Indonesia are not without attention, especially in the East Java province, which is in the top five of the region with the highest incidence of diabetes mellitus in Indonesia. This study aims to raise awareness among the government and the public about preventing and controlling diabetes. The research method used is quantitative. The data used in this study are secondary data obtained from the East Java Basic Health (Riskesdas) Research in 2018. Based on the results of the study found that the consumption of fatty foods, the population that has never checked blood sugar levels, the nutritional status based on the body mass index (BMI) category with the characteristics of obesity, as well as the population who has never consumed fruit and vegetables were the most influential factors in the increase in the prevalence of diabetes mellitus in East Java in 2018 with an adjusted R-squared value of 79%.
Keywords: Diabetes Melitus, East Java, 2018, Stepwise Linear Regression, Robust Linear Regression
 
Abstrak
Di antara penyakit tidak menular, diabetes melitus menjadi salah satu penyumbang angka kematian terbesar. Penyakit ini juga disebut silent killer karena tanda-tandanya sulit diketahui dan upaya pencegahannya sulit untuk dilakukan. Kasus penyakit diabetes melitus di Indonesia pun tidak luput dari perhatian, khususnya di Provinsi Jawa Timur yang berada pada posisi lima besar dari keseluruhan provinsi dengan penyandang penyakit diabetes melitus tertinggi di Indonesia. Tujuan penelitian ini adalah sebagai penambah wawasan baik kepada pemerintah maupun masyarakat mengenai seberapa penting upaya pencegahan dan pengendalian diabetes melitus. Metode penelitian yang digunakan merupakan metode kuantitatif. Data yang digunakan pada kajian ini adalah data sekunder yang diperoleh dari Riset Kesehatan Dasar (Riskesdas) Jawa Timur pada 2018. Berdasarkan hasil penelitian, diperoleh bahwa konsumsi makanan berlemak, masyarakat yang tidak pernah memeriksa kadar gula darah, status gizi berdasarkan kategori Indeks Massa Tubuh (IMT) dengan karakteristik obesitas, serta masyarakat yang tidak pernah mengkonsumsi buah dan sayur merupakan faktor yang paling berpengaruh terhadap peningkatan prevalensi penyakit diabetes melitus di Jawa Timur pada tahun 2018 dengan nilai adjusted R-squared sebesar 79%.
Kata Kunci: Diabetes Melitus, Jawa Timur, 2018, Stepwise Linear Regression, Robust Linear Regression
Korelasi Kadar Fenol dan Flavonoid terhadap Indeks Aktivitas Antioksidan Ekstrak Batang Vernonia amygdalina
Authors: Awwaliah Mardhatillah , Mukhriani Mukhriani , Asma Nur , Arsul Muhammad Ikhlas
Published: January 2024

Bitter leaf (in Africa) is the most widely cultivated species of the genus Vernonia which is the most prominent in the family Asteraceae that has been studied in Africa. African leaves have been widely used for traditional medicine and/or treating various human diseases. This study aimed to determine the bioactive compounds that correlate to the antioxidant activity of V. amygdalina stem. Extraction of V. amygdalina stem was carried out by reflux method. Determination of total phenol and flavonoid content was done spectroscopically. Antioxidant activity was measured based on antioxidant activity index (AAI) using DPPH and CUPRAC methods. Correlation coefficient between bioactive compounds and antioxidant activity using Pearson's correlation method. The results showed the antioxidant activity index of V. amygdalina stem showed strong to very strong activity. The ethyl acetate extract showed the highest total phenol and flavonoid levels. The phenol and flavonoid content of V. amygdalina stem extract showed a strong and significant correlation to the antioxidant activity index with a positive r value
Kata Kunci:         AAI, DPPH, CUPRAC, pearson’s correlation
 
Abstrak
Daun afrika merupakan spesies yang paling banyak dibudidayakan dari genus Vernonia yang paling menonjol dalam famili Asteraceae yang telah dipelajari di Afrika. Daun afrika telah banyak digunakan untuk pengobatan tradisional dan/atau mengobati berbagai penyakit pada manusia. Tujuan dari penelitian ini adalah untuk mengetahui senyawa bioaktif yang berkorelasi terhadap aktivitas antioksidan dari batang V. amygdalina. Ekstraksi batang V. amygdalina dilakukan dengan metode refluks. Penentuan kadar  fenol dan flavonoid total dilakukan secara spektroskopi. Aktivitas antioksidan diukur berdasarkan indeks aktivitas antioksidan (AAI) dengan metode DPPH dan CUPRAC. Koefisien korelasi antara senyawa bioaktif dan aktivitas antioksidan menggunakan metode korelasi pearson’s. Hasil penelitian menunjukkan indeks aktivitas antioksidan batang V. amygdalina menunjukkan aktivitas yang kuat hingga sangat kuat. Kadar fenol dan flavonoid total tertinggi ditunjukkan pada ekstrak etil asetat. Kadar fenol dan flavonoid ekstrak batang V. amygdalina menunjukkan korelasi kuat dan signifikan terhadap indeks aktivitas antioksidan dengan nilai r positif.
Kata Kunci:         AAI, DPPH, CUPRAC, korelasi pearson’s
Toxicity of Anti-Inflammatory Substances in Hemigraphis Alternata Leaves: In Silico Study Using ProTox-II
Authors: Yeni Yeni , Rachmania Rizky Arcinthya
Published: January 2024

Hemigraphis alternata is empirically used to treat wounds. Hemigraphis alternata leaves ethyl acetate extract can assist in resolving the inflammatory process by inhibiting enzymes that play a role in the inflammatory cycle. Twenty-two substances found in the leaves of Hemigraphis alternata were predicted to have an anti-inflammatory effect by inhibiting cyclooxygenase-1 (COX-1) or 5-lipoxygenase (5-LOX) as an enzyme target. In-silico toxicology was carried out to acquire new anti-inflammatory drugs with low toxicity from 22 compounds. ProTox-II was utilized to measure the level of toxicity of these drugs at many endpoints. In this study, five compounds have LD50 > 5000 mg/kg body weight, toxicity class 5-6, and inactive for cytotoxicity, carcinogenicity, hepatotoxicity, mutagenicity and immunotoxicity parameters. They are 2-methyleneoctanenitrile, nerolidol, 2,7-dioxa-tricyclo[4.4.0.0(3,8)]deca-4,9-diene, 9,9-dimethoxybicyclo[3.3.1]nonane-2,4-dione, and phytol.
Keywords:          in silico, toxicity, Hemigraphis alternata, anti-inflammatory, ProTox-II
Classification of Elementary Cellular Automata Based on Their Limit Cycle Lengths in Z/k
Authors:   Berlin, Germany, Stricker Hans-Peter
Published: January 2024

In this paper we introduce a classification of elementary cellular automata based solely on numerical properties of the lengths of their limit cycles on finite lattices Z/k. The classification has a formal definition, and it could in principle be proved whether a given cellular automaton belongs to a given class. It will remain open if this is generally possible, that is, if the question is decidable.
Turing Patterns in Networks
Authors:   Center for Applied Physics and Advanced Technology National Autonomous University of Mexico, Durán Elizabeth Alejandra Ortiz , Verde Daniel Ivan Parra ,   Center for Applied Physics and Advanced Technology National Autonomous University of Mexico
Published: January 2024

The first pattern formation model was proposed by the mathematician Alan M. Turing. This model consists of a system of reaction-diffusion equations that produces stationary patterns by means of the so-called “Turing instability.” In this paper, we found the conditions that the network and the parameters need to fulfill in order to achieve the Turing instability in a particular reaction-diffusion system called the Mimura–Murray model on different network topologies, including some simulations on an innovative kind of network, based on the Wolfram model, that evolves over time, generating interesting topologies that exhibit lattice-like topology. In addition, the equations are solved and simulated in Wolfram Language, and some examples of applications in biology and sociology are presented.
Affinity Classification Problem by Stochastic Cellular Automata
Authors:   Department of Computer Science and Engineering National Institute of Technology, Bhattacharjee Kamalika , Paul Subrata , Das Sukanta ,   Department of Information Technology Indian Institute of Engineering Science and Technology,   Department of Information Technology Indian Institute of Engineering Science and Technology
Published: January 2024

This paper introduces the affinity classification problem, which is a generalization of the density classification problem. To solve this problem, we introduce temporally stochastic cellular automata where two rules are stochastically applied in each step on all cells of the automata. Our model is defined on a two-dimensional grid having affection capability. We show that this model can be used in several applications, such as modeling self-healing systems.
DESCANSOS ACTIVOS: OPTIMIZACIÓN DE TIEMPO, GRADOS ESCOLARES Y TIPOS
Authors: Javier Ninahuaman Henry Juan , Rojas Ginche Ali Edmundo , Canchumanya Popi Juan , Alderete Callupe Liz , Arauzo Gallardo Carlos , Quispe Santivañez Grimaldo
Published: January 2024

El estudio optimiza el logro de rendimiento académico mediante las variables: grado escolar, el tipo de recreo y el tiempo de interrupción de clases. Mediante un método cuantitativo, longitudinal, experimental y superficial de respuesta de diseño compuesto central en orden de 26 corridas, con puntos axiales y centrales (-1,0,1). Sus resultados indican valores óptimos de logro de rendimiento académico (92,8%) cuando aplica recreos de mente plena con parámetros de interrupciones cada 44.84 minutos en los grados de estudio segundo y tercero de secundaria (2.81). Concluye que el recreo activo de mente plena getra mejor rendimiento académico que el lúdico.
Scale-up studies for production of α-amylase by A. Tamarii MTCC5152 and development of enzyme product
Authors: Premalatha A. , Vijayalakshmi K. , Suseela Rajakumar G.
Published: January 2024

α-amylases are one of the most vital commercially produced starch hydrolyzing enzymes. Increasing enzyme production is becoming one of the most important goals in biotechnological processes. In this study, the production of α-amylase by A.tamarii MTCC5152 in flask level studies is experimentally validated by scale-up studies in Koji room under controlled conditions using wheat bran, a low cost agro-industrial waste as substrate. The production of amylase was increased by optimising various culture conditions such as inoculum size, incubation period and moisture content. It was found that A.tamarii MTCC5152 produced highest titre of α-amylase activity (668.01 u/g), after 4 days of incubation period at 5% inoculum concentration and 80% moisture content. The results of the comparative analysis of protease and amylase production demonstrated 15% increase in α- amylase and 20% increase in protease production compared to flask level studies. Studies conducted for the development of enzyme products as liquid enzyme concentrate and dry enzyme powder showed that addition of hydrophilic agents such as poly ethylene glycol (PEG- 6000) was found to be an effective way to increase the activity and enzyme yield in the preparation of a dry enzyme powder using A.tamarii MTCC5152. The ammonium sulfate precipitated enzyme at saturation, lyophilized by freeze drying gave the best recovery (96%) of the enzyme activity.
Development of HIV Therapeutic Approaches based on Nanotechnology
Authors: Ahuja Palash , Rami Esha , Prasad Kiran , Shaikh Javid
Published: January 2024

Acquired Immune Deficiency Syndrome appears to be one of the major threats to humankind and is a serious health problem and a fast-spreading incurable disease. Numerous antiviral medications and nucleic acid therapies, including siRNA, have been researched and assessed for HIV prevention due to the virus' complex structural makeup and the absence of a potential vaccine. The antiviral treatments have considerably improved the quality and hope of life for the infected people, but along with the capacity to adapt to the virus, it has prevented further success. HIV primarily affects the body's cell-mediated immune system. It is concentrated in specific inaccessible areas of the body such as the CNS, lymphatic system and macrophages where the majority of therapeutic drugs cannot reach in sufficient concentrations or for the required period. With the introduction of highly active antiretroviral therapy, the prevalence of HIV/AIDS infections is decreasing. Drug resistance and physical obstacles to antiretroviral therapy are still major problems. Different nanocarriers with the stimuli-responsive release are proposed for antiretroviral agents. These include creating nanoparticles with passive and active targeting capabilities as well as ones that can react to a variety of internal and external triggers. Many of the advantages of the lipid system can also be offered by nanocarriers. For the treatment of HIV/AIDS, drug delivery systems such as liposomes, solid lipid nanoparticles, dendrimers and polymeric nanoparticles are being studied. This study seeks to provide an overview of how nanocarrier technology can offer a logical approach to anti-HIV therapy.
Logopedyczne zajęcia grupowe dla dzieci różnych narodowości - w poszukiwaniu metod
Authors: Grzesiak-Witek Danuta
Published: January 2024

Logopedzi wciąż stoją przed koniecznością poszukiwania skutecznych, a zarazem ciekawych dla dzieci metod terapeutycznych. Kreatywny logopeda to taki, który wciąż poszukuje nowych metod w swojej pracy terapeutycznej. Zajęcia logopedyczne odbywają się zarówno w formie indywidualnej, jak i grupowej. Grupowe zajęcia logopedyczne mają wiele zalet, gdyż sprzyjają nawiązywaniu relacji między dziećmi. Poza tym w przypadku uczniów z zaburzeniami mowy, ćwicząc z rówieśnikami nie czują się oni izolowani ze względu na swoje problemy z mówieniem. Zajęcia grupowe są dla dzieci interesujące, jeżeli logopeda zaproponuje ciekawe gry i zabawy. W przypadku szkół, do których uczęszczają dzieci różnych narodowości należy tak poprowadzić zajęcia, by mogły w nich wziąć udział wszyscy uczniowie i by okazały się one korzystne dla całej grupy. Autorzy niniejszego tekstu inspiracji podczas poszukiwania metod terapeutycznych dla grupowych zajęć logopedycznych poszukują w dydaktyce. Artykuł prezentuje możliwości zastosowania wybranych metod nauczania podczas grupowych zajęć logopedycznych, przedstawiając propozycje w następujących kategoriach: metody o charakterze integracyjnym, metody rozwijające słownictwo, metody usprawniające umiejętności syntaktyczne i metody doskonalące wymowę. Zaprezentowane metody zapożyczone z dydaktyki stanowią tylko niewielki wybór metod, jakie można zastosować po adaptacji w logoterapii. Należy zachęcić logopedów do dalszych poszukiwań metod terapeutycznych nie tylko na terenie dydaktyki.
Dwutekst jako element kategorii radialnej przekładów wybranego tekstu
Authors: Jóźwiak Jolanta
Published: January 2024

W artykule zaprezentowano próbę zastosowania kognitywnej teorii prototypów w badaniach przekładoznawczych na poziomie makrojednostki, jaką stanowi dwutekst, czyli para tekstów: oryginał i przekład, postrzegane i rozpatrywane łącznie.
Zgodnie z takim ujęciem zaproponowano trzy modele teoretyczne kategorii przekładów wybranego tekstu. Oprócz modelu ogólnego przedstawiono również kategorię z przekładem prototypowym oraz kategorię z modelem mentalnym przekładu jako elementami pary dwutekstów, znajdujących się w centrum kategorii.
Centralno-peryferyjna struktura kategorii pozwala zwizualizować stopień przybliżenia do ideału poszczególnych, realnych lub tylko potencjalnych dwutekstów. Modele mogłyby również być przydatne w o odnalezieniu odpowiedzi na pytanie, dlaczego w ocenie odbiorców właśnie ten, a nie inny przekład utworu zyskał uznanie lub stracił status albo przy ocenie wariantów przekładowych w seriach przekładowych.
The analysis of second language learners’ difficulties
Authors: Świątek Artur , Pluszczyk Adam
Published: January 2024

Analiza trudności uczących się drugiego języka: przypadek polskich uczniów uczących się języka angielskiego
W artykule omówiono trudności, z którymi mierzą się uczący się drugiego języka. W części teoretycznej przedstawiono podstawowe założenia analizy kontrastowej (contrastive analysis), analizy błędów (error analysis), międzyjęzyka, a także i różne źródła błędów przez nich popełnianych.
W artykule skoncentrowano się na analizie błędów, które mogą wystąpić podczas procesu uczenia się. Zwrócono uwagę na problemy, przed którymi stoją polscy uczniowie uczący się języka angielskiego. Analiza oparta została zarówno na korpusie pisemnym, jak i mówionym, czyli PELCRA, pozwalających zidentyfikować różne błędne przykłady użycia zaobserwowane wśród uczniów uczących się drugiego języka.
Selection of an effective affinity sorbent for the isolation of proteins with sialidase activity from human blood serum
Authors: Суркова Р.С. , Каширских Д.А. , Собенин И.А. , Орехов А.Н.
Published: January 2024

Целью исследования было определить эффективный аффинный сорбент для выделения белков, обладающих сиалидазной активностью, из сыворотки крови человека. Материалы и методы. Для получения белков, обладающих сиалидазной активностью, было использовано четыре аффинных сорбента: 1) иммобилизованная на агарозе трисиаловая кислота Neu5Ac(α2-8)Neu5Ac(α2-8)Neu5Ac, 2) иммобилизованный на агарозе дериват сиаловой кислоты (Neu5Acα)3 -C3-PAA-biot, 3) иммобилизованный на агарозе дериват сиаловой кислоты 5-amino-Neu2en, 4) иммобилизованный на агарозе дериват сиаловой кислоты 4-aminoNeu5Ac2en. Выделение белков, ответственных за десиалирование липопротеидов низкой плотности (ЛНП), проводили с помощью электрофореза в градиентном полиакриламидном геле. Результаты. Показано, что наиболее эффективно связывает белки, обладающие нейраминидазной активностью, сорбент с (Neu5Acα)3 -C3-PAA-biot. При проведении электрофореза полученных элюатов выделяются белки с молекулярной массой 65 и 116 кДа.

The aim of the study was to determine an effective affinity sorbent for isolating proteins with sialidase activity from human blood serum. Materials and methods. Four affinity sorbents were used to obtain proteins with sialidase activity: 1) Neu5Ac(α2-8)Neu5Ac(α2-8) Neu5Ac trisialic acid immobilized on agarose, 2) sialic acid derivative (Neu5Acα)3-C3-PAA-biot immobilized on agarose, 3) sialic acid derivative immobilized on agarose 5- amino-Neu2en, 4) agarose-immobilized sialic acid derivative 4-amino-Neu5Ac2en. Isolation of the proteins responsible for LDL desiallation was performed using gradient polyacrylamide gel electrophoresis. Results. The sorbent with (Neu5Acα)3 -C3-PAA-biot most effectively binds proteins with neuraminidase activity. During electrophoresis of the obtained eluates, proteins with a molecular weight of 65 and 116 kDa are isolated.
Cognitive rehabilitation of motor movement
Authors: Пальцын А.А. , Свиридкина Н.Б.
Published: January 2024

Нарушения двигательных функций можно восстановить двигательной активностью. Способность к движению поддерживается движением. При сокращении или утрате последнего, сокращается или утрачивается первое. Развивается ситуация «порочного круга». Поэтому жизненно важна ранняя и эффективная реабилитация ослабленной или утраченной моторной способности. В лекции представлены некоторые свидетельства того, что трудновыполнимому в такой ситуации разрыву «порочного круга» можно способствовать воображаемым движением – двигательными образами активировать механизмы физической двигательной моторики.

Violations of motor functions can be restored by motor activity. The ability to move is maintained by movement. With the reduction or loss of the latter, the former is reduced or lost. A vicious circle is developing. Therefore, early, and effective rehabilitation of impaired or lost motor ability is vital. The lecture provides some evidence that the imaginary movement can help break the vicious circle, which is difficult to achieve in such a situation, motor images activate the mechanisms of physical motor motility.
High-Performance BiVO4 Photoanodes: Elucidating the Combined Effects of Mo-Doping and Surface-Modification with Polyoxometalate Co-Catalysts
Authors: Feng Fan , Mitoraj Dariusz , Gong Ruihao , Gao Dandan , Elnagar Mohamed , Liu Rongji , Beranek Radim , Streb Carsten
Published: January 2024

Doping and surface-modification by co-catalysts are well-established strategies for the performance enhancement of bismuth vanadate (BiVO4) photoanodes for photoelectrochemical (PEC) water splitting devices. However, our knowledge of the complex effects of doping and surface modification that govern the PEC performance is still underdeveloped, which makes the rational design of high-performance BiVO4-based photoanodes challenging. Herein, a remarkably effective strategy for enhancing the performance of BiVO4 photoanodes by combining the bulk doping of BiVO4 with molybdenum (Mo) and its surface modification with a well-defined molecular cobalt polyoxometalate water oxidation catalyst (CoPOM = Na10[Co4(H2O)2(PW9O34)2]) via a simple impregnation protocol without any linkers or binders is reported. The best-performing optimized Mo-BiVO4/CoPOM photoanode exhibits a photocurrent density of 4.32 mA cm−2 at 1.23 V vs. RHE under AM 1.5G (1 sun) illumination and an applied-bias photoconversion efficiency (ABPE) of ~0.73%, which is an improvement by the factor of ~24 with respect to pristine BiVO4. The respective contributions of the Mo-doping and modification with CoPOM to the performance enhancement are disentangled based on detailed mechanistic investigations. The positive effect of Mo-doping is shown to be related to enhanced electronic conductivity and passivation of surface states, whereby these beneficial effects are operative only at relatively high applied bias potentials (> 0.9 V vs. RHE), and at lower bias potentials (< 0.7 V vs. RHE) they are counterbalanced by strongly detrimental effects related to increased concentration of electron polaronic states induced by the Mo-doping. The highly beneficial effect of CoPOM deposition is unambiguously demonstrated to be related to the enhancement of water oxidation catalysis. Notably, the molecular CoPOM acts as a pre-catalyst, as it undergoes (at least partially) conversion to cobalt oxide under the PEC operating conditions. Our work thus establishes CoPOM-derived catalysts as effective water oxidation catalysts at BiVO4 photoanodes, and suggests that further progress in BiVO4 photoanode development depends critically on devising alternative strategies for conductivity enhancement that would avoid the negative polaronic effects associated with the conventional bulk doping of BiVO4.
Unraveling Surface Chemistry of SnO2 Through Formation of Charged Oxygen Species and Oxygen Vacancies
Authors: Shaban Tameh Maliheh , L. Gladfelter Wayne , Goodpaster Jason
Published: January 2024

Understanding the properties of the adsorbed oxygen species on the SnO2 surface is essential in describing the reaction mechanisms responsible for gas sensing applications. We perform density functional theory (DFT) calculations to shed light on these mechanisms by exploring the energetics of molecular, atomic, and dissociative oxygen adsorption on various types of reduced, defective, and stoichiometric SnO2(110) surfaces. Through the charge analysis, we distinguished various forms of charged oxygen species on the surface. Our calculations identified the existence of O_2^(2-), O_2^-, and O^(2-) on the reduced surface and O_2^(2-), O^-, and O^(2-) on the defective and the oxidized surfaces. The role of oxygen vacancies in recognizing the adsorption modes and relevant properties is demonstrated. The described electronic structure in this work supports experimental findings.
Selective (a)-L-Rhamnosylation and Neuroprotective Activity Exploration of Cardiotonic Steroids
Authors: Rutkoski Ryan , Debarba Lucas Kniess , Stilgenbauer Lukas , Rosenthal Tay , Sadagurski Marianna , Nagorny Pavel
Published: January 2024

This work describes the studies on the direct C3-glycosylation of the C19-hydroxylated cardiotonic steroids strophanthidol, anhydro-ouabagenin and ouabagenin using a strategy based on in situ protection of the C5 and C19 hydroxyl groups with boronic acids. While this strategy resulted in a successful one-pot C3-selective glycosylation of strophanthidol and anhydro-ouabegenin, it failed to provide ouabain from ouabagenin. The neuroprotective activity of the synthetic and natural glyco-sides against LPS-induced neuroinflammation was explored in neonatal mice primary glia cells. Co-administration of natural and synthetic C3-glycosides at 200 nM concentrations resulted in the significant reduction of the LPS-induced neuroinflam-matory markers IL-6, IL-1, TNFα, and IKBKE, with the anhydro-ouabagenin-3-(a)-L-rhamnoside (anhydro-ouabain) show-ing the most significant effect. At the same time, unglycosylated anhydro-ouabagenin enhanced rather than suppressed LPS-induced neuroinflammation.
CHARACTERISTICS OF LOCAL PUMP SCHEMES REUSING DRAINAGE WATER IN A MAJOR RICE-BASED IRRIGATION AND DRAINAGE AREA IN THE RED RIVER BASIN, VIETNAM
Authors: Chinh Le Van , Jensen Jens Raunsø
Published: January 2024

A comprehensive study was undertaken in a major rice-based irrigation and drainage area, with the objective of assessing the characteristics and importance of the wide-spread use of drainage water from canal irrigation schemes by local schemes. The irrigated area of 18,308 ha consisted of the public managed Cau Son canal scheme and 208 electric-powered pump schemes, of which 109 were classified as drainage reuse schemes using drainage water from the canal scheme. The reuse pump schemes covered 27% of the irrigated area, including 6 public and 103 local managed pump stations, the latter with about 21,000 households engaged in reuse irrigation. The local schemes were typically 25 years old and showed a high degree of variability in irrigated area, total dynamic head, design capacity, and energy use. The seasonal irrigation delivery ranged by a factor 10 with about 65% “lost” in return flow mostly as surface drainage. The use of electric power was excessive, associated with low pumping and irrigation efficiencies related to poor maintenance, inadequate water management and capacity overdesign. A significant scope was identified for improved use of water and energy and for integrating local reuse schemes in performance evaluations and water management frameworks in canal-irrigated areas.
INFILTRATION AND COLMATATION DYNAMICS ON PHYSICAL MODELS STUDY BY INFILTRATION BASINS AT ARTIFICIAL GROUNDWATER RECHARGE
Authors: Absametov M.K. , Murtazin E.Zh. , Kulagin V.V. , Makyzhanova A.T. , Ismagulova A.Zh.
Published: January 2024

The problem of the growing shortage of water resources in the world, including in the territory of South-East Kazakhstan, due to global warming and aggravated by long distances to natural sources of good quality water, requires the combined use of surface water and groundwater from local aquifers to supply the local population with high-quality drinking water. The application of methods of artificial groundwater spreading can be an effective way only if positive characteristics of soil and soil parameters of the aeration zone and productive aquifers are obtained in the processes of infiltration and colmatation, which are one of the decisive indicators for ensuring productivity and duration of operation of infiltration basins in the given mode. This work presents the main results of complex field studies of the processes of infiltration and colmatation in infiltration mini-basins at pilot sites within the Aksu, Lepsy and Koksu river valleys, taken as typical for the territory of South-Eastern Kazakhstan, which most needs to increase the water supply of rural population settlements and remote pastures. These studies were supplemented by a detailed assessment of the water-physical, hydrodynamic and filtration properties of the overburden and the upper layers of the aquifer. The new data showed that the infiltration rate varied from 15 m/day at the beginning to 0.75 m/day at the end and remained practically unchanged by the end of the experiment. This was largely facilitated by the values of the heterogeneity coefficient of the granulometric composition of all the examined soils obtained during the studies, which did not exceed 3.0 due to the uniform distribution of coarse fractions and a small proportion of loams and sandy loams. Approximately one month after the start of the tests, a colmatation layer began to be generated at the bottom of the mini-ponds, the thickness of which by the end of the test reached from 3 mm for clay silt to 6 mm for silty clay. However, as studies have shown, the generation of a colmatation layer due to the settling of suspended particles of surface water did not significantly impact on the infiltration processes, as evidenced by the rated values of specific flow rates, which in the final period of time ranged from 0.86 to 0.75-0.80 m3/day per square meter of reduced infiltration surface. Thus, the generated positive results of field studies can serve as a factual basis for design, and can also be recommended and accepted as design indicators both at the stage of a feasibility study and at the stage of detailed design of artificial groundwater spreading systems without additional labor-intensive and costly survey works, and the approved methodology for their implementation will be useful when conducting similar studies in other regions.