bluuebunny/crossref_metadata_2025 huggingface dataset:
The New Era of Globalism: Redefining Globalisation through International Initiatives, Alliances and Associations
Authors: Bawa Tejvir , R Singh Anmol
Published: May 2024

Globalisation, as the world’s transformative phenomenon, is emblematic of the convergence of diverse nations under an encompassing network characterised by intricate economic structures, moral frameworks, and shared political foundations. The contemporary iteration of globalisation is undeniably intertwined with the interests and strategic motivations of nationstates. Nevertheless, this manifestation grapples with three fundamental challenges: it impedes the progress of unfettered global trade, thus hindering the global economic agenda; it propagates disparities and exerts detrimental effects on democratic governance; and it does not consistently align with democratic principles. The dynamic interplay and diplomatic engagements among nations have spawned a well-defined international trade and cooperation framework. Notably, a novel paradigm of “alliance or coalition globalisation” is materialising, eclipsing national interests in favour of regional prosperity and shared interests among diverse nations. This evolving concept introduces a new “invisible hand” in the global capitalist model, focusing on regional economic development and connectivity as top priorities for modern nation-states. Consequently, it safeguards and advances regional interests. This paper elucidates how these emerging coalitions serve as catalysts for a global paradigm shift, reconfiguring the landscape of economic and commercial interactions worldwide. The mandates include upholding territorial integrity, non-interference by international organisations in domestic affairs, balanced roles within the global order, reforming the United Nations Security Council, and ensuring that a limited number of countries no longer dictate international objectives. This new wave of globalisation promises to reshape global dynamics to reflect a more equitable and cooperative international landscape.
Differentiated Instruction: A Survey of Novice Teachers’ Understanding and Barrier to Implementation
Authors: Kanapathy Suganty
Published: May 2024

Gifted and talented students have different interests and preferred learning styles. Scholarly investigations have demonstrated that teaching gifted and talented students must address their needs as well as nurture their talents. Meeting the needs of gifted students in diverse classrooms has become a major problem for teachers. Differentiated instruction is one of the methods of instruction used with gifted children in programs. The idea that coping with all students equally is no longer effective, especially among gifted students. This emphasizes the importance of suitable teaching approaches, which include differentiated instruction (DI) as a fundamental solution, although challenging. Thus, this research aims to evaluate the level of understanding and the barriers faced by novice teachers in the implementation of differentiated instruction. This study was conducted at a boarding school located in Malaysia. The data were collected using a quantitative approach. The collected data were analyzed using SPSS software. The research revealed that novice teachers generally have knowledge and implement differentiated instruction during class. However, the amount of time taken for preparation becomes the major barrier to the implementation of differentiated instruction. The study also highlighted the need for professional development courses to support the implementation of differentiated instruction for gifted students.
Keberkesanan Pembelajaran Berasaskan Metaverse Melalui Aplikasi Zepeto bagi Subjek Sains di kalangan Murid Sekolah Rendah
Authors: Lam Mei Wei , Norman Helmi
Published: May 2024

Dunia pendidikan telah mengalami transformasi yang ketara seiring dengan kemajuan teknologi. Salah satu pendekatan inovatif terkini yang semakin mendapat perhatian di peringkat global ialah pembelajaran berasaskan metaverse menggunakan aplikasi seperti Zepeto, Roblox dan Minecraft. Kajian ini bertujuan untuk menilai keberkesanan aplikasi Zepeto sebagai platform dalam meningkatkan pencapaian dan minat murid terhadap subjek Sains di kalangan murid sekolah rendah. Kajian ini menggunakan pendekatan kuantitatif dan kajian kuasi-eksperimen yang menggunakan reka bentuk ujian pra-pasca satu kumpulan. Seramai 29 orang murid dari sebuah sekolah rendah di Negeri Sembilan dipilih sebagai responden kajian melalui persampelan mudah. Analisis deskriptif dan inferensi dijalankan menggunakan perisian Pakej Statistik Sains Sosial (SPSS) versi 26. Ujian-t dua sampel bersandar menunjukkan skor ujian pasca secara signifikan lebih tinggi berbanding dengan skor ujian pra, t(28) = -9.581, p < 0.05. Terdapat peningkatan pencapaian skor ujian murid dengan perbezaan min skor antara ujian pasca dan ujian pra sebanyak 13.79. Analisis deskriptif pula menunjukkan tahap minat murid dalam pembelajaran berasaskan metaverse melalui aplikasi Zepeto berada pada tahap yang tinggi. Analisis ujian korelasi Pearson menunjukkan wujudnya hubungan linear positif yang sederhana dan signifikan antara skor ujian pasca dan minat murid [r(27) = 0.429, p < 0.05]. Kajian ini menunjukkan bahawa aplikasi Zepeto berpotensi digunakan sebagai salah satu pendekatan pembelajaran yang dapat meningkatkan pencapaian dan minat murid sekolah rendah terhadap subjek Sains. Penggubal dasar dan para pendidik boleh memanfaatkan dapatan kajian ini untuk meningkatkan kualiti pembelajaran Sains di kalangan murid sekolah rendah di Malaysia melalui penerapan teknologi metaverse dalam kurikulum pendidikan Sains di masa depan.
A Relevância do Employer Branding na Atração e Retenção de Talentos em Startups
Authors: Castellini Amanda Moreira , Silva Luiz Henrique , Rios Juliana Estácio , Tessarini Junior Geraldo
Published: May 2024

O objetivo deste artigo consistiu em analisar a relevância do Employer Branding em startups, no que diz respeito à atração e retenção de talentos. No referencial teórico, foram abordadas a bases conceituais da pesquisa, englobando os conceitos de Employer Branding e startups. Os procedimentos metodológicos empregados envolveram entrevistas semiestruturadas online com 9 profissionais de Recursos Humanos que atuam em startups de diferentes segmentos, presentes na lista de 2021 das Melhores Empresas para Trabalhar. Os resultados encontrados demonstraram que uma marca empregadora forte, que transmite a cultura, os valores e o propósito da empresa, é um fator determinante para atrair candidatos alinhados com a organização. Também foram identificadas algumas ações que contribuem para a permanência dos empregados nas startups. Como conclusão, ficou evidente a relevância do Employer Branding nas startups, especialmente no que diz respeito à atração e retenção de talentos.
Improving the Welfare of Poor Families through theFamily Hope Program
Authors: Bola Pati Plasida Angelina , Sukardi  , Wahyudi Catur
Published: May 2024

In Indonesia, the problem of poverty remains a significant concern regarding the government's efforts to improve society's social welfare. Poverty and unemployment are considered significant challenges that must be overcome immediately. The Family hope program(PKH) is one of the government's initiatives to reduce poverty and promote social protection. Even though it can be seen that the Family hope programhas run as expected, it is open to obstacles/things that are not by this program. The problem relatedto PKH in Ngegedhawe Village is regarding the validity of PKH participant eligibility data, resulting in errors in the use offunds given to poor households for things not recommended in the Family hope program. This research aims to describe and analyze how the Family hope programpolicy is implemented and to describe and analyze the supporting and inhibiting factors in the process of implementing the Family hope programpolicy in order to improve the welfare of poor and vulnerable families based on the Minister of Social Affairs Regulation of the Republic of Indonesia Number 10 of 2017 concerning the Family Program Hope. This research method is descriptive qualitative, focusing on communication indicators, resources, disposition, and bureaucratic structure. The results of this research show that the Family hope programin Ngegedhawe Village, Aesesa District, Nagekeo Regency is seen from the communication variable, there is socialization and training for Beneficiary Families, in theresource variable, thereare many parties involved, very minimal human resources, there is staff appointment using which has been determined by the local government in the disposition variable as well as, there is a precise distribution of responsibility and coordination among work units based on the main tasks and functions of each in the bureaucratic structure variable
The Political Behavior of the Batulanteh Highlands Community in the Regional Head Election of Sumbawa Regency in 2020
Authors: Ardiyansyah  , Ngarawula Bonaventura , Sukardi
Published: May 2024

his research aims to determine the political behavior of voters and the factors behind them choosing the people of the Batulanteh highlands in the 2020 Sumbawa Regency regional elections. This is interesting to research becauseeach voter has their own reasons and interests in determining political choices, so that candidates can determine strategy in campaigning to get results that are in line with the target. This study is qualitative research. The results of the research showthat the tendency for political behavior to vote for the people of the Batulanteh highlands tends to be dominated by aspects of the figure and campaign issues as well as the candidate's work program. This is closely related to the real condition of Batulanteh which is still very underdeveloped and far from development aspects. The factors behind the political behavior of Batulanteh Community voters are the voter's social circle as a variable that is outside the voter but has an influence in determining individual political choices. Individual voters' decisions are strongly influenced by group cohesion processes, not purely individual decisions and actions. This creates a "threat" if an individual in a group makes a decision that is different from the group's decision, including the decision not to vote. Then there are patron client relationships, money politics, and an assessment of regional socio-economic conditions. Of the various aspects above, the most determining aspect is money politics. Meanwhile, thepatron-client aspect is relative, one-off, and not literate. The existence of money politics is considered the most determinant in influencing a person's voting decisions. This is caused by the Covid-19 pandemic, making money politics easier to accept andincreasing nominal vote buying. Money politics succeeded in influencing voting behavior because candidates used personal loyalist strategies to influence voters through their social environment. The use of money politics is an effort to strengthen voters'preferences for certain candidates and strengthen the confidence of regional head candidates to be able to get guaranteed voter compliance
Management of Green Open Spaces in the Malang City Region, Indonesia
Authors: Aditya Putra Rio Alif , Wahyudi Catur , Widjajani Roos
Published: May 2024

Based on Malang City Regional Regulation Number 4 of 2011 concerning Regional Spatial Planning in Malang City, regulations have been regulated regarding the existence, management, and availability of green open space in Malang City as an ecological balance in the Malang City area. However, this policy has only partially influenced green open space development, especially city parks. So currently, the Malang City government is managing and revitalizing several green open spaces (RTH) areas and city parks; even though they need to be improved, such funding problems hamper them. This research uses descriptive research with a qualitative approach. The research location was carried out at the Malang City Environmental Service. The data sources are primary data and secondary data. The data collection techniques used were observation, interviews, and documentation. For data analysis techniques in this research, we use techniques from Miles and Huberman, namely data collection, data condensation, data presentation, and data verification. The research results explain that budget problems have resulted in managing green open spaces limited to maintenance activities. This can be seen from indicators in policy implementation, which include the communication factor, namely the clarity of policy orders from the city government to the implementing organization, even though there has been no form of socialization to the public. The next factor is resources in the form of limited regional income and expenditure budgets, limiting the management of green open spaces. The third factor is good cooperation and coordination between related areas and regional apparatus organizations from within and outside the organization, such as the private sector or corporate social responsibility (CSR).Fourth, the bureaucratic structure, namely the organizational structure, the appropriate division of tasks and functions, and standard operational procedures have been implemented in green open space for the environmental service.
Digital Empowerment:Transforming Rural Women through Digital Marketing Skills in the District of Fatehgarh Sahib
Authors: Makkar Diksha , Jai Singh Konica , Panesar Hema , Gupta Robin , Singh Mejie Thakur , Singh T.P.
Published: May 2024

Women empowerment means giving equal power and opportunities to women as men without any kind of discrimination. The role of NGOs has shifted from merely ‘gap-filling’ to ‘capacity building and empowerment’. Mehar Baba Charitable Trust, Bassi Pathana, Punjab, India has beenselected by CFLI1for the project. This project has helped women in many ways to lead from the front and be part of decision-making at the local level. This project aimed at empowering rural women in Fatehgarh Sahib through the acquisition of digital marketing skills.The study is based on primary and secondary sources of data collection. The present study analyses and evaluates the implementation of the project and itsimpact on the society. The findings highlight that involving stakeholders from the mobilization to follow-up processes has a long-term impact on society as a whole. Women broke the chains of their traditional roles and stepped out of their four walls to learn new skills and set an example for other women in society. By assessing the current knowledge and challenges faced by these women, a tailored training program was developed and implemented. Additionally, it explored the role of mentorship and support networks in sustaining their success. The findings from this research will inform future scalability and replication of the project in other regions
International experience in implementing ESG sustainable development strategy in the restaurant business
Authors: Машин Д.В. , Русакович М.В.
Published: May 2024

Статья посвящена изучению зарубежного опыта использования ESG-принципов в разработке стратегии устойчивого развития организаций ресторанного бизнеса. По результатам исследования был установлен генезис ESG-методологии, особенности применения ESG-принципов в мировой практике, а также проведена оценка уровня развития применения ESG-принципов организациями ресторанного бизнеса.

The article is devoted to the study of foreign experience in using ESG principles in developing a strategy for sustainable development of restaurant business organizations. Based on the results of the study, the authors established the genesis of ESG methodology, features of the application of ESG principles in world practice, and also assessed the level of development of the application of ESG principles by restaurant business organizations.
Ontology of statistical indicators of yield time series for forecasting by machine learning methods
Authors: Рыжова О.А.
Published: May 2024

В статье раскрывается сущность онтологии как альтернативной современной базы данных, которая представляет собой формальное описание знаний из домена, учитывающее связи всех элементов, для выявления новых факторов и взаимосвязей. Ризонинг позволяет выявить в онтологии похожие данные. Чтобы составить прогноз, необходимо систематизировать полученные данные. Не всегда удобно использовать таблицы, поэтому возникла система организации знаний в виде графов – онтология. Прогноз, составленный на основе временных рядов, получается более точным. Для моделирования принято использовать параметрические и непараметрические модели, линейные и нелинейные модели, одномерные и многомерные модели. Точный прогноз урожайности составить сложно, так как многие параметры временных рядов заранее неизвестны, но их необходимо учесть при моделировании. Сложно проанализировать статистические показатели с использованием нелинейных методов прогнозирования. Необходимо как можно меньше использовать факторы, дающие большое среднеквадратическое отклонение векторов входа и выхода.

This article reveals the essence of ontology as an alternative modern database, which is a formal description of knowledge from the domain, taking into account the connections of all elements, in order to identify new factors and relationships. Risoning allows you to identify similar data in the ontology. To make a forecast, it is necessary to systematize the data obtained. It is not always convenient to use tables, so there was a system of organizing knowledge in the form of graphs – ontology. The forecast based on time series is more accurate. It is customary to use parametric and nonparametric models, linear and nonlinear models, one-dimensional and multidimensional models for modeling. It is difficult to make an accurate yield forecast, since many time series parameters are unknown in advance, but they must be taken into account when modeling. It is difficult to analyze statistical indicators using nonlinear forecasting methods. It is necessary to use as little as possible the factors that give a large standard deviation of the input and output vectors.
Exploring the potential of artificial intelligence in auditing and accounting
Authors: Чунихина Т.Н. , Золкин А.Л. , Матвиевская Т.Б. , Маринов А.Д.
Published: May 2024

В статье исследуются ключевые аспекты интеграции алгоритмов машинного обучения в аудите и бухгалтерском учете с акцентом на анализе связанных с ними проблем, рисков и преимуществ. Рассмотрены принципы функционирования и практического применения интеллектуальных систем в бухгалтерии и аудите, выявлены проблемы и потенциальные риски, связанные с методами машинного обучения. Придается значимость анализу региональных специфик в использовании нейронных сетей в областях бухгалтерского учета и аудита, что способствует идентификации ограничений, связанных с данной технологией. Сделан вывод о потенциале использования выявленных данных для разработки методик эффективного применения искусственного интеллекта в бухгалтерских и аудиторских операциях.

The article explores the key aspects of integrating machine learning algorithms in auditing and accounting, with an emphasis on analyzing the problems, risks and benefits associated with them. The principles of functioning and practical application of intelligent systems in accounting and auditing are considered, problems and potential risks associated with machine learning methods are identified. The importance is attached to the analysis of regional specifics in the use of neural networks in the fields of accounting and auditing, which helps to identify the limitations associated with this technology. The conclusion is made about the potential of using the identified data to develop methods for the effective use of artificial intelligence in accounting and auditing operations.
On the issue of the subjects of extremism: common features and peculiarities
Authors: Амшоков А.Х.
Published: May 2024

В статье рассматриваются характеристики и особенности экстремизма, который может появляться не только в результате политической, но и культурной, общественной деятельности органов государственной власти. Данный вопрос следует изучать в комплексе субъектов, понятий и сущности, так как это неразрывные элементы рассматриваемого явления.

The article examines the characteristics and features of extremism, which can appear not only as a result of political, but also cultural, social activities of public authorities. This issue should be studied in a complex of subjects, concepts and essence, since these are inseparable elements of the phenomenon under consideration.
Effects of Community Participation on School Infrastructure Development in Rural Uganda
Authors: Ngwama Christine
Published: May 2024

Purpose: The aim of the study was to investigate the effects of community participation on school infrastructure development in rural Uganda.
Methodology: This study adopted a desk methodology. A desk study research design is commonly known as secondary data collection. This is basically collecting data from existing resources preferably because of its low cost advantage as compared to a field research. Our current study looked into already published studies and reports as the data was easily accessed through online journals and libraries.
Findings: Community participation in rural Uganda positively impacts school infrastructure development by fostering ownership and ensuring cultural relevance. Local contributions reduce costs and speed up construction, though variable participation and limited skills can pose challenges. Strong community engagement is essential for the success and sustainability of these projects.
Unique Contribution to Theory, Practice and Policy: Social capital theory, stakeholder theory & asset-based community development (ABCD) theory may be used to anchor future studies on the effects of community participation on school infrastructure development in rural Uganda. Establish regular feedback mechanisms through community meetings, surveys, and online platforms. Governments and educational authorities should formulate policies that support and mandate community involvement in all phases of school infrastructure development.
Implication of Institutional Frameworks Governing Land Tenure Security in Social-Economic Dynamics: Experience from Iringa District in Tanzania
Authors: Usika Gerald , Urassa Justin , Kabote Samwel
Published: May 2024

Purpose: The study aimed to examine the implication of institutional frameworks governing land tenure security in socioeconomic dynamics in the Iringa district. The study used the case of the Iringa district to investigate the institutional framework that provides implications for the governance of land tenure security in Tanzania.
Methodology: The study employed phenomenography by collecting primary data from 16 key informants selected from village and district levels. Data from key informants were complemented by documentary review with perception considered deductively.  
Findings: Findings confirmed the existence of two principal institutional frameworks; the Land Act No. 5 of 1999 and the Village Land Act No. 4 of 1999. Nonetheless, bureaucracy, inadequate policy dissemination, and poverty emerged as primary causes of deviations in land policy implementation in the study area. This study concludes that the successful implementation of Tanzania's land policy in the Iringa District Council has significantly facilitated land tenure security through the issuance of a Certificate of Customary Right of Occupancy. Establishing a robust institutional framework and clear land use rules has been central to this success. However, challenges such as complex Certificate of Customary Right of Occupancy acquisition procedures, bureaucracy, inadequate policy dissemination, and prevalent poverty in rural areas have been identified as impediments.
Unique Contribution to Theory, Practice and Policy: The study was guided by Institutional Theory which describes the interaction of human beings with existing natural resources, the institution involves the regulation of formal rules from constitutions, status laws, and other legal frameworks controlling the interaction and relationship of human behavior. The study contributed to the theory by establishing the relationship between the organization and enforcement of policy and regulatory framework that governs land tenure. Also, the study recommends expanding the Certificate of Customary Right of Occupancy issuance, strengthening local land administration, simplifying land use regulations, facilitating easier access to Certificate of Customary Right of Occupancy especially for impoverished households, and implementing strategies to reduce bureaucracy and enhancing policy understanding at the grassroots level. These measures aim to enhance land tenure security and support sustainable development in rural communities.
The use of multimedia technologies in english lessons
Authors: Толешова Мухаббат , Хилкеева Дилноза
Published: May 2024

In recent years, the question of using new multimedia technologies in education has been raised more and more often. These are not only new technical means, but also new forms and methods of teaching, a new approach to the learning process. The main goal of teaching foreign languages is the formation and development of the communicative culture of students, training in practical mastery of a foreign language.
Improvement of listening skills in teaching a foreign language in primary classes
Authors: Абатов Аралбай
Published: May 2024

The article presents ways aimed at improving the listening skills of pupils of primary classes at schools.
Comparing and levelling process in typology and translation
Authors: Конисов Г , Уразниязова Г Уразниязова
Published: May 2024

The article deals with the process of comparison and stages of levels in comparative typology and translation in modern linguistics. Some types of techniques in comparing two or more languages are suggested.
Семантикалық примитивлердиң улыўма лингвистикалық статусы
Authors: Кудайбергенова Сапиура
Published: May 2024

Семасиология илиминиц ксйинги жыллардагы рауажланыуы бизди мэни аддийсесиниц тэбиятына тэн сырларын инсан когнитив искерлиги ҳэм қэбилети шецберинен излеў керсклигинс тагы бир марте иссндирмсктс. Семантика когнитив тил билиминиц ажыралмас белеги, керек болса, тийкарына айланып атырганлыгына гуўа болып турмыз [1,311]
Integrating Augmented Reality and Simulation Game for Flower Board Design
Authors: Pratiwi Eka , Triase Triase , Sinaga Imam Adlin
Published: May 2024

Augmented Reality was regarded as one of the technologies that merged the real world with the virtual one. Its development was carried out by developers across various fields, including businesses such as floral services, exemplified by Berkah Florist. In practical application, Berkah Florist encountered challenges related to efficiency and customer satisfaction in the floral design process. The prevailing methods, such as displaying photographs or employing paper-based designs, were time-consuming and susceptible to paper damage, thus hindering customers from expressing their preferences accurately and disrupting the design process. To address these challenges, an application was developed to streamline the floral design process, aiming to make it more appealing. This research aimed to assist customers and streamline Berkah Florist's operations by facilitating the modeling and visualization of more captivating and effective designs. The application, based on a simulation game, was developed using Research and Development (R&D) and Rapid Application Development (RAD) methodologies. The application presented floral designs through an AR-enabled camera, replicating real-world conditions. The incorporation of Augmented Reality in the application garnered interest and engagement from prospective customers while alleviating boredom. Designed to provide a delightful experience for potential customers, the application aimed to enhance their interest in reusing it. Consequently, Berkah Florist could enhance customer experience and improve efficiency in the floral design process.
Utilization of Data Analytics to Enhance Operational Efficiency in Manufacturing Companies
Authors: Aprijal Rendi , Siregar Iqbal Wiranata , Siahaan Andysah Putera Utama , Marlina Leni
Published: May 2024

In the digital era, manufacturing industries confront challenges like heightened global competition and intricate production processes, urging them to boost efficiency and productivity. Amidst these circumstances, Big Data emerges as a pivotal opportunity to enhance manufacturing performance. Big Data, characterized by vast volumes of data, utilizes advanced data mining to machine learning techniques for analysis. Data analytics, an interdisciplinary field, profoundly impacts manufacturing operations, enabling deeper insights into production processes. By analyzing production data, companies identify inefficiencies, streamline workflows, and enhance operational efficiency and productivity. Predictive maintenance through sensor data analysis prevents machine failures, while logistics data analysis optimizes supply chains and inventory management, reducing costs and enhancing competitiveness. However, implementing Big Data analytics presents challenges such as rapid data growth, diverse data sources, real-time insights, skill shortages, and data fragmentation. Overcoming these hurdles requires robust technology, skilled personnel, and effective data management strategies. Examples of Big Data analytics applications include customer behavior analysis by Amazon and Netflix, fraud detection in insurance, and urban mobility optimization. Success factors in data analytics implementation include effective data-driven communication, technology integration, and skill enhancement. In conclusion, implementing Big Data Analytics in manufacturing promises significant benefits in operational efficiency, product quality, and competitiveness. Overcoming challenges necessitates robust strategies and consideration of ethical and security issues, ensuring responsible data usage. With a deep understanding of Big Data Analytics, manufacturing companies can leverage this technology to achieve higher efficiency and competitiveness in the global market.
3-Hydroxypropanal (Reuterin) the Overlooked Cyclophosphamide Metabolite
Authors:   Institute of Biochemistry II, Goethe University Frankfurt Medical School, Frankfurt  Germany, Voelcker Georg
Published: May 2024

Cyclophosphamide (CP) is one of the oldest anticancer drugs, but one that is also highly effective by today’s standards
Combined Microbial Fermentation Converts Bioactive Compounds in Nitraria Tangutorum Bobrov Fruit and Displays its Antidiabetic Potential
Authors:   Nanjing Vinson Biotech Co. Ltd, Nanjing China, Yang Isabelle Fan , Liub Changhong ,   School of Life Science, Nanjing University, Nanjing China
Published: May 2024

Nitraria tangutorum Bobrov is a berry shrub with white flowers and red fruits, which grows in the deserts in the Tibetan Plateau, Mongolia, and western China. Its fruit N. tangutorum Fruit (NTF) contains various bioactive compounds, with anti-fatigue, anti-inflammatory, and neuroprotective functions. However, the high saccharide content of NTF makes it unsuitable for diabetic patients. In this study, we fermented NTF to obtain N. tangutorum Fermented Juice (NTJ), and N. tangutorum Fermented Residue (NTR), which are suitable for diabetics to consume. We characterized the bioactive compounds in NTF, NTR, and NTJ, and found that fermentation increased the diversity of bioactive compounds, and greatly reduced sucrose, glucose, and fructose content while generating trehalose, which has the potential to manage blood glucose levels. Further, NTJ displays anti-diabetic potential due to various compounds anti-diabetic properties. This study provides a basis for further clinical research on NTJ’s anti-diabetic function in humans.
The Effectiveness of Integrative Therapy (Short-Term Psychodynamic and Cognitive-Behavioral Therapy) in Enhancing the Ego Strength and Treating Depression (Case Study), with Follow-Up
Authors:   Faculty of Psychology and Educational Sciences, Alzahra University, Iran, Orvati Aziz Marzieh
Published: May 2024

Depression is a common and serious disorder that has negative effects on the way a person thinks and functions. The purpose of the present study was to evaluate the effectiveness of integrative therapy (short-term psychodynamic and cognitive behavioral therapy) in increasing ego strength and treating depression in a case of major depressive disorder. In this study, a single-subject research design (A-B-A-B design) was used and the client was evaluated during the four stages of beginning, middle, and end of treatment and six months of follow-up by the Beck Depression Inventory and Inventory of Ego Strengths. The results showed the effectiveness of integrative therapy in increasing ego strength, reducing depression, and improving the quality of life of the client.
Washing Out the Septic Knee
Authors:   Department of Internal Medicine, University of Michigan Health System, USA, W. Ike Robert
Published: May 2024

Abstract Effective drainage of joint purulence is a key component of the management of the septic knee. Methods from arthrocentesis to open arthrotomy and arthroscopy are mainstays, with different efficacies and morbidities. Percutaneous tube instillation techniques have been employed since World War I. Methods to effect joint distension and irrigation to mimic what is accomplished at arthroscopy employed over the past 65 years have been honed to a simple bedside technique since the 80s and applied successfully in management of several different arthritides, including septic arthritis. Wider employment of this technique has the potential to more effectively treat the septic knee, particularly when access to O.R. based procedures is limited, as well as allow usage by physicians who do not perform arthroscopy.
Unusual Penetrating Mandibular Injury By A Cut-Off Wheel
Authors:   Department of Université De Sousse-Tunisie, Tunisia, Mabrouk Haythem , Ben Rejeb Maha ,   Department of Université De Sousse-Faculté De Médecine De Sousse-Tunisie, Tunisia
Published: May 2024

Penetration wounds on the face caused by foreign bodies other than bullets are rare in today’s life. Most of the adult penetrating injuries reported in the literature were due to industrial accidents, criminal assaults or self-injury. We present an unusual case of a man who suffered a fracture of his lower jaw due to a broken cut- off wheel. This kind of injuries was rare in todays life because of the Poor workplace safety still existing in our country.
The Natural Autoimmunity: Self-Recognition, Self-Interaction, and Self-Maintenance
Authors:   Anokhin Institute of Normal Physiology, MRC Immunculus, Russia, Poletaev Alexander
Published: May 2024

Within the last 20-30 years, the field of clinical immunology has been subject to some paradoxes that contradict the positions adopted by most physicians.
Diabetes and the Heart
Authors:   Diabetes Institute of Ireland, Beacon Clinic and Trinity College, Ireland, H. Tomkin Gerald , Owens Daphne ,   Diabetes Institute of Ireland, Beacon Clinic and Trinity College, Ireland
Published: May 2024

Treatment of diabetes has improved in recent years and has resulted in reduction in mortality and in particular atherosclerotic heart disease. Heart failure with preserved LV function is becoming more common in obese diabetic and non diabetic patients resulting in recurrent hospitalisation and increased mortality. A major cause may be the decreased fitness and reduction in exercise that often accompanies obesity and Type 2 diabetes. Although hyperglycaemia plays an important part in heart failure with preserved LV ejection fraction the disease may start with a much lower ‘abnormal’ blood sugar suggesting that our current definition of diabetes should be reconsidered.
Bioequivalence of Two Perampanel 12mg Tablets in Healthy, Adult, Human Subjects under Fed Conditions - An Open Label, Cross Over Study
Authors:   AZIDUS Laboratories Ltd, India, Arumugam Arjun , Lakshmi Geetha ,   AZIDUS Laboratories Ltd, India, G Srinivas ,   AZIDUS Laboratories Ltd, India, Rao Nageswara ,   AZIDUS Laboratories Ltd, India, J Chirinos ,   Abbott Laboratories de Colombia, M Perez ,   Abbott Laboratories de Colombia, Gavino-Gutiérrez Arquímedes ,   Abbott Laboratories de Colombia
Published: May 2024

Background: Perampanel is a glutamate non-competitive receptor antagonist that is effective as adjunctive therapy for epilepsy. The main objective of the present research is to compare the bioavailability and to evaluate the bioequivalence between the test and reference product. The secondary objective is to assess the safety and tolerability of the drug
Securing Messages and Files Using Integrated Steganography and Asymmetric Encryption Techniques
Authors: Shamsi Sayed Ehsan , Nasrat Bebe Wajiha
Published: May 2024

Steganography and Cryptography are two popular ways of sending vital information in a secret way. One hides the existence of the message and the other distorts the message itself. As we know, after the improvement of internet, the security or privacy of information and data are the most important factors of Information Technology and communication. Every day, large quantities of data are transferred via the internet, file sharing site, social networking sites and etc. simultaneously, the number of internet users are also increases. This article aims to develop a user-friendly program that would address the security concerns in message delivery to authorized parties safely, at least to some extent. We applied C# language in order to make the application work fast and by the time the user selects the file and image, immediately after pressing the Encryption button within few seconds the process will complete. This evaluation showed that users fund this application easy to use and likely to be useful during message passing through steganography and cryptography methods.
University Students’ Perception of Quality: A Case of Bangladesh
Authors: Mamun Muhammad Ziaulhaq , Talukder Sazidur Rahman
Published: May 2024

This paper explored the quality perception of university students of Bangladesh in terms of 57 quality dimensions. A total of 258 responses from both public and private universities with different demographics are considered using non-probability convenient sampling technique. The responses are found reliable and valid. The most important quality dimensions observed by the respondents are value for money, completeness, privacy, serviceability, performance, durability, accurate quantity, reliability, taste, sound, easy identification, and conformance. The very close to highly agreed attributes are quality certification, ease of use, responsiveness, timeliness, hygienic/cleanliness, accuracy, easy installation, competency, and accessibility and convenience. On the other hand, the least agreed quality dimensions as perceived by the respondents are appealing facilities, packaging/look, prestige, financial facilities, foreign good, advertisement, loyalty program, financially sound brand, CSR, celebrity endorsement. Of the 29 quality attributes of goods, the study identified good value, performance, serviceability, durability, reliability, sound, easy identification, conformance, taste, ease of use, easy set-up as the most important quality dimensions. Interestingly the students give less emphasis on natural and cognitive based quality attributes. On the other hand, of the 18 service quality attributes, the respondents found completeness, accuracy, cleanliness, timeliness, responsiveness, and accessibility & convenience as most important quality attributes. Further, of the ten quality constructs common to both service and manufacturing items the respondents identified privacy of information and quality certification as the most important. On the other extreme the least agreeable attributes are financially sound companies, CSR activity, and celebrity endorsement. Demography and ideography wise no significant difference is observed in the study.
HUMAN SECURITY PARADIGM: IMPLICATIONS OF THE US-CHINA STRATEGIC CONFLICT IN WESTERN PACIFIC
Authors: Zulqarnain  , Nizamani Siraj Ahmed , Dure Shehwar
Published: May 2024

Western Pacific region is extremely important owing to its political, economic, and geo-strategic importance. For decades, the region has witnessed the hegemony of the USand its strong collaboration with multiple states of Far East. However, the recent rise of China regarding political influence, economic development, and military might have posed challenges to the US hegemonic designs increasing the prospects for a strategic conflict. The resulting surge in China’s assertiveness has also fuelled hostile emotions among states. This paper explores the ramifications of emerging strategic conflict between the US and China using the Human Security Paradigm (HSP). By employing qualitative research method paper articulates that the implications of strategic conflict in Far East can be a challenge to national interests of the US. Given the different nature of human security issues and their propensity to exacerbate the conflict, the paper advocates using preventive measures when dealing with human security problems.
INNOVATIVE APPLICATION OF CERAMIC ART IN MODERN PRODUCT DESIGN IN CHINA
Authors: Qiumei Qu
Published: May 2024

With the passage of times, modern product design are getting increased importance to respective cultural connotation. Only products with unique cultural connotation can occupy a place in the market, and ceramic culture is the treasure of traditional culture. Therefore, ceramic materials are used as the carrier of product design, and fashionable elements such as ceramic culture, modelling and decorative patterns are embellished in product design. So it can not only reflect the profound cultural connotation of the product, but also have unique aesthetic characteristics. With the product as the medium, the essence of Chinese tradition continues to the field of modern people's life, gives the product a new connotation, and better reflects The Times, so that the ceramic culture not only has the connotation of national culture and art, but also has the emotion and charm of modern design.
Hubungan Stigma Diri dengan Tingkat Stres Pada Pasien TB Paru di Rumah Sakit Khusus Paru Sumatera Utara Tahun 2023
Authors: Saragih Ice Septriani , Sigalingging Vina Yolanda Sari , Sitohang Kristina Octavia
Published: May 2024

Background: Self-stigma is a negative feeling experienced by pulmonary TB sufferers which causes feelings of shame and shunning, so they tend to limit themselves when interacting with other people, and can result in tension from within themselves due to stress. Objective: To determine the relationship between self-stigma and stress levels in pulmonary TB patients at the North Sumatra Specialized Lung Hospital in 2023. Method: Using quantitative research with a cross sectional design. The total population is 1105, the sampling technique is purposive sampling, with a total sample of 47 respondents. The instrument used was a questionnaire. Results: The low category of self-stigma was 21 respondents (45%), the medium category was 17 respondents (36%), the high category was 9 respondents (19%), the stress level was in the light category as many as 18 respondents (38%), the medium category was 16 respondents (34%) and the weight category was 13 respondents (28%). The results of the Spearman Rank (rho) statistical test obtained a value of r = (0.432) and p (value) = 0.001 (p<0.05). Conclusion: These results indicate that there is a relationship between self-stigma and the stress level of pulmonary TB patients at the Special Lung Hospital in North Sumatra.
Homenaje a Ronald R. Tasker
Authors: Vilela Filho Osvaldo
Published: May 2024

Homenaje a Ronald R. Tasker
Reseña de eventos: I Reunión Conjunta Brasilero-Argentina de Neuromodulación (RECOBRAN). II Reunión Internacional Conjunta de Neurocirugía Funcional y Estereotaxia
Authors: Vilela Filho Osvaldo
Published: May 2024

La Primera Reunión Conjunta Brasileño-Argentina de Neuromodulación (I RECOBRAN) y la Segunda Reunión Internacional Conjunta de Neurocirugía Funcional y Estereotaxia se llevaron a cabo en la ciudad de Goiania, capital del estado de Goiás, Brasil, durante los días 17 al 20 de noviembre del 2010 y consolidó la interacción entre las sociedades científicas de Brasil y Argentina en este creciente campo de la Neurocirugía Funcional en América Latina.
Gammapatía biclonal transitoria posterior a infección por SARS-CoV-2. Reporte de un caso
Authors: Rodríguez Pizarro N , Conte Lanza G , Samaniego F
Published: May 2024

Los pacientes infectados por SARS-CoV-2 presentan un curso clínico variable, desde asintomáticos o con síntomas respiratorios leves hasta una evolución grave con gran reacción inflamatoria e inmune. La aparición de un componente monoclonal como manifestación de este estado inflamatorio e inmune está poco descrito. Se presenta el caso de un paciente masculino de 74 años que inicia en 2020 con síndrome anémico, livedo reticularis y acrocianosis, gatillados por frío y aliviados por calor. El laboratorio evidencia anemia hemolítica por anticuerpos fríos y su estudio complementario es compatible con enfermedad por crioaglutininas. Se trata con rituximab sin respuesta, posteriormente recibe rituximab-bendamustina resolviendo síntomas, disminuyendo el título de crioaglutininas, mejorando la anemia y normalizando el perfil bioquímico. En febrero de 2022 presenta neumonía multifocal por SARS COV 2, requiriendo hospitalización por 19 días, con reactivación mínima de su enfermedad de base. En esta etapa se detecta en electroforesis e inmunofijación en suero dos componentes monoclonales IgG kappa e IgG lambda, sumados a su IgM kappa conocido por su enfermedad por crioaglutininas. El seguimiento muestra que dichos componentes persisten detectables por 4 meses, pero un control posterior evidencia la persistencia de sólo IgM kappa en inmunofijación, con desaparición de los nuevos componentes. La electroforesis es también negativa. Usualmente las infecciones virales generan hipergammaglobulinemias policlonales, en contraste mostramos como en este caso la infección por SARS-CoV-2 se asocia a gammapatía biclonal transitoria, la que planteamos como manifestación de la intensa reacción inmune generada por el virus.
Linfomas no Hodgkin de células B en Panamá: realidad de un centro de referencia nacional
Authors: Salehji A , Cooke A
Published: May 2024

Introducción. Los linfomas no Hodgkin (LNH) representan aproximadamente el 3% de todos los cánceres diagnosticados a nivel mundial y, dentro de las neoplasias linfoides, representan un 90% del total. Panamá no cuenta con ningún estudio epidemiológico sobre los LNH y tampoco se han publicado datos que evidencien nuestra realidad en cuanto a esta entidad neoplásica, por lo que resulta necesario conocer los datos de esta entidad heterogénea. Material y métodos. Estudio observacional, retrospectivo, analítico, de corte transversal realizado en un centro de tercer nivel de complejidad. La muestra del estudio corresponde a 196 pacientes. Se evaluaron los expedientes físicos y digitales de cada uno de los casos. La información recolectada fue analizada mediante el programa SPSS 25.0. El objetivo principal es determinar las características clínicas y epidemiológicas de los pacientes con LNH de células B incluidos en el estudio. Resultados. 53% de los pacientes incluidos en el estudio corresponden al sexo masculino y 47% al sexo femenino. 74.8% debutaron en estadios avanzados de la enfermedad, relacionado proablemente a que un porcentaje similiar reportó síntomas B. El linfoma difuso de células B grandes representa el subtipo más frecuente con más del 60% de los casos registrados. Valores de LDH >500 U/L y la presencia de síntomas B se asociaron a menor sobrevida global. Discusión. Las características epidemiológicas, clínicas y terapéuticas de nuestra oblación son similares a las descritas en la región. Sin embargo, existe una mayor proporción de pacientes que debutan con síntomas B y estadíos avanzados de la enfermedad. Se pudieron validar en nuestra población, factores de mal pronóstico descritos en otras latitudes.