Modern investigation of cervico-vaginal infections (from microbiome disorders to pelvic inflammatory disease)
Authors:   Departament of Obstetrics and Gynecology, Emergency University Hospital, Bucharest, Romania, Calinescu Gina , Bohiltea Roxana Elena ,   Departament of Gynecology and Obstetrics, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania,   Department of Obstetrics and Gynecology, Filantropia Clinical Hospital, Bucharest, Romania, Balan Andra Magdalena ,   Departament of Obstetrics and Gynecology, Emergency University Hospital, Bucharest, Romania, Georgescu Tiberiu Augustin ,   Department of Pathology, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Bacalbasa Nicolae ,   Departament of Obstetrics and Gynecology, Emergency University Hospital, Bucharest, Romania,   Department of Visceral Surgery, Center of Excellence in Translational Medicine, “Fundeni” Clinical Institute, Bucharest, Romania, Balescu Irina ,   Department of Visceral Surgery, Ponderas Academic Hospital, Bucharest, Romania, Mihai Bianca Margareta ,   Department of Obstetrics and Gynecology, Filantropia Clinical Hospital, Bucharest, Romania, Dima Vlad ,   Department of Obstetrics, Gynecology and Neonatology, Filantropia Clinical Hospital, Bucharest, Romania, Vladareanu Ioana Teodora ,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Salmen Teodor ,   Doctoral School, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania,   “N.C. Paulescu“ National Institute of Diabetes, Nutrition and Metabolic Disorders, Bucharest, Romania, Grigoriu Corina ,   Departament of Obstetrics and Gynecology, Emergency University Hospital, Bucharest, Romania,   Departament of Gynecology and Obstetrics, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
Published: May 2022

Vaginitis is the general term for disorders of the vagina caused by infection, inflammation, or changes in the normal vaginal flora, while cervicitis refers to inflammation of the uterine cervix. Symptoms of vaginitis include vaginal discharge, pruritus, odor, and/or discomfort. Women with cervicitis may have presenting symptoms such as purulent or mucopurulent (yellow) vaginal discharge, intermenstrual or postcoital bleeding, dysuria, vulvovaginal irritation and dyspareunia. The initial evaluation typically consists of a medical history, physical examination, microscopy examination of vaginal swab, and cervical tests for sexually transmitted infections. Evaluation of patient risk factors is important and should include a detailed discussion about the sexual history (number of partners, type of sexual activity, condom use, new sex partner, sex partner with a diagnosed sexually transmitted infection, sex partner with concurrent sex partners), vaginal hygiene (douching), and age (< 25). All women with symptoms suggestive of cervicitis or vaginitis undergo a physical examination that includes pelvic and vaginal evaluations. Vaginitis is often the result of the presence of infectious agents. The most common infections, such as bacterial vaginosis, Candida vulvovaginitis and trichomoniasis, account for over 90 percent of the vaginal infections. Cervicitis, typically acquired from sexually transmitted infections such as gonorrhea, chlamydia, and mycoplasma, can present with nonspecific vaginal symptoms.