bluuebunny/crossref_metadata_2025 huggingface dataset:
Somatic Mutations Drive Distinct Imaging Phenotypes in Lung Cancer
Authors: Rios Velazquez Emmanuel , Parmar Chintan , Liu Ying , Coroller Thibaud P. , Cruz Gisele , Stringfield Olya , Ye Zhaoxiang , Makrigiorgos Mike , Fennessy Fiona , Mak Raymond H. , Gillies Robert , Quackenbush John , Aerts Hugo J.W.L.
Published: June 2017

Tumors are characterized by somatic mutations that drive biological processes ultimately reflected in tumor phenotype. With regard to radiographic phenotypes, generally unconnected through present understanding to the presence of specific mutations, artificial intelligence methods can automatically quantify phenotypic characters by using predefined, engineered algorithms or automatic deep-learning methods, a process also known as radiomics. Here we demonstrate how imaging phenotypes can be connected to somatic mutations through an integrated analysis of independent datasets of 763 lung adenocarcinoma patients with somatic mutation testing and engineered CT image analytics. We developed radiomic signatures capable of distinguishing between tumor genotypes in a discovery cohort (n = 353) and verified them in an independent validation cohort (n = 352). All radiomic signatures significantly outperformed conventional radiographic predictors (tumor volume and maximum diameter). We found a radiomic signature related to radiographic heterogeneity that successfully discriminated between EGFR+ and EGFR− cases (AUC = 0.69). Combining this signature with a clinical model of EGFR status (AUC = 0.70) significantly improved prediction accuracy (AUC = 0.75). The highest performing signature was capable of distinguishing between EGFR+ and KRAS+ tumors (AUC = 0.80) and, when combined with a clinical model (AUC = 0.81), substantially improved its performance (AUC = 0.86). A KRAS+/KRAS− radiomic signature also showed significant albeit lower performance (AUC = 0.63) and did not improve the accuracy of a clinical predictor of KRAS status. Our results argue that somatic mutations drive distinct radiographic phenotypes that can be predicted by radiomics. This work has implications for the use of imaging-based biomarkers in the clinic, as applied noninvasively, repeatedly, and at low cost. Cancer Res; 77(14); 3922–30. ©2017 AACR.
Emerging Data and Current Challenges for Young, Old, Obese, or Male Patients with Breast Cancer
Authors: Freedman Rachel A. , Partridge Ann H.
Published: June 2017

There are distinct subgroups of patients who have historically been underrepresented in most prospective clinical trials in breast cancer, including the youngest and oldest patients, male patients, and those struggling with obesity. Herein, we review current and future directions in research for each of these special populations with breast cancer, highlighting significant knowledge gaps and priorities in tumor biology and heterogeneity, therapeutic decision making promotion of adherence, supportive care, and psychosocial and functional well-being. In younger women, future study should focus on the biological underpinnings of aggressive disease and optimizing adherence and treatment decision making while addressing their unique survivorship needs. The latter includes generating a scientific basis for interruption of therapy for pregnancy. Among older patients, interventions should focus on increasing clinical trial accrual, predicting and mitigating toxicity so that functional status can be optimized, tailoring needs for dose modification, and anticipating life expectancy in the context of competing causes of death. For men with breast cancer, we need worldwide collaboration to answer even basic questions on optimal treatment, supportive care, and survivorship strategies. Finally, for those struggling with obesity, we need to better understand the biological associations with cancer incidence, prognosis and outcome, and how we can best intervene to assure weight loss at the “right time.” It is only through highly collaborative, far-reaching, prospective, multidisciplinary, patient-centered, and patient-engaged efforts that we can optimize the physical and psychologic outcomes for all patients with breast cancer. Clin Cancer Res; 23(11); 2647–54. ©2017 AACR.

See all articles in this CCR Focus section, “Breast Cancer Research: From Base Pairs to Populations.”
Interplay between elevated cellular fibronectin and plasma fibrin clot properties in type 2 diabetes
Authors: Konieczyńska Małgorzata , Bryk Agata , Malinowski Krzysztof , Draga Katarzyna , Undas Anetta
Published: June 2017

Type 2 diabetes is associated with faster formation of poorly lysable, denser fibrin clots and elevated cellular fibronectin (cFn), a marker of vascular injury. We investigated whether cFn affects clot properties in type 2 diabetes. In 200 consecutive patients with type 2 diabetes and 100 control subjects matched for age and sex, we determined plasma cFn along with clot formation and degradation using turbidimetric and permeability assays. Diabetic patients had elevated cFn (median, 3.99 [interquartile range, 2.87–4.81] µg/ml]), increased clot density (MaxAbsC) and prolonged lysis time (LysT) compared with those without type 2 diabetes (all p<0.01). Diabetic patients with documented cardiovascular disease (CVD, n=127, 63.5 %) had increased cFn (4.53 [3.68–4.95] µg/ml), decreased clot permeability (Ks) and increased MaxAbsC compared with those without CVD (all p<0.001). Diabetic patients with cFn in the top quartile (>4.81 µg/ml) were two times more likely to have CVD compared with those in the lowest quartile (odds ratio 1.80, 95 % confidence interval 1.41–2.46, p<0.001). No differences in cFn were observed in relation to microvascular complications. After adjustment for potential confounders, cFn accounted for 10.2 % of variance in Ks, 18.2 % of variance in clot density and 10.2 % of variance in AUC in diabetic patients. This study shows that elevated cFn is associated with unfavourably modified clot properties in type 2 diabetes, especially with concomitant CVD, which indicates novel links between vascular injury and prothrombotic alterations in diabetes. Coagulation, cellular fibronectin, type 2 diabetes, cardiovascular disease.

Supplementary Material to this article is available online at www.thrombosis-online.com.
Introduction to this special section: Iran
Authors: Zadeh Siamak , Foster Douglas J.
Published: June 2017

Iran has been a major player in oil and gas exploration and production since the early twentieth century. However, for nearly 40 years, little information on petroleum-related activities in Iran has been published in the United States or, to a large extent, globally. Political turmoil has isolated Iran since the late 1970s, but recent events have changed the situation and many of the internationally imposed sanctions have been lifted. Some international companies have started to engage Iran to partner in development and exploration activities.
Seismic rock physics
Authors: Amato del Monte Alessandro
Published: June 2017

Rock physics studies the relationship between physical and elastic properties of rocks and is the basis of quantitative seismic interpretation. It has arguably given exploration geophysicists a solid quantitative basis to their interpretation of seismic data. It can be tackled at different scales of investigation by people with various backgrounds — from geophysicists to civil engineers, from mathematicians to petrophysicists.
Predictive properties of risk assessment instruments following self-harm
Authors: Owens David , Kelley Rachael
Published: June 2017

This month's BJPsych publishes two important studies concerned with the use of risk assessment scales after self-harm, one a systematic review and the other a multicentre cohort study. We agree with the authors: that each study adds weight to the existing evidence that points towards avoiding the use of such scales in clinical practice.
The Land in Gorkhaland
Authors: Besky Sarah
Published: June 2017

Darjeeling, a district in the Himalayan foothills of the Indian state of West Bengal, is a former colonial “hill station.” It is world famous both as a destination for mountain tourists and as the source of some of the world’s most expensive and sought-after tea. For decades, Darjeeling’s majority population of Indian-Nepalis, or Gorkhas, have struggled for subnational autonomy over the district and for the establishment of a separate Indian state of “Gorkhaland” there. In this article, I draw on ethnographic fieldwork conducted amid the Gorkhaland agitation in Darjeeling’s tea plantations and bustling tourist town. In many ways, Darjeeling is what Val Plumwood calls a “shadow place.” Shadow places are sites of extraction, invisible to centers of political and economic power yet essential to the global circulation of capital. The existence of shadow places troubles the notion that belonging can be “singularized” to a particular location or landscape. Building on this idea, I examine the encounters of Gorkha tea plantation workers, students, and city dwellers with landslides, a crumbling colonial infrastructure, and urban wildlife. While many analyses of subnational movements in India characterize them as struggles for land, I argue that in sites of colonial and capitalist extraction like hill stations, these struggles with land are equally important. In Darjeeling, senses of place and belonging are “edge effects”: the unstable, emergent results of encounters between materials, species, and economies.
MODELING WORK HANGING PILES
Authors: Дыба Владимир , Dyba Vladimir , Скибин Геннадий , Skibin Gennadiy
Published: June 2017

The article discusses a mathematical model of the dive the basis of the pile into the ground-tion. The authors have proposed a new method for determining the bearing capacity of piles of hanging
The experimental research results of the influence of the shape of the contact surface of the basement to the deformable subgrade.
Authors: Наумкина Юлия , Naumkina Ulia , Пронозин Яков , Pronozin Yakov , Рачков Дмитрий , Rachkov Dmitriy
Published: June 2017

The article presents the analysis of the results of field experimental study of the effect of the contact surface forms of the foundation on the deformability of subgrade. Experimental data show peculiarities of intensely deformed state of subgrade loaded on a curved concave contact surface. Stiffening of the base in this case is due to higher modulus of deformation of soil deformation in the core base, due to the additional lateral compression of soil, relating to a form of the contact surface.
ABOUT THE COMMERCIALIZATION OF SCIENTIFIC AND TECHNOLOGICAL ACTIVITIESIN THE CONSTRUCTION INDUSTRY
Authors: Абжалимов Раис , Abzhalimov Rais
Published: June 2017

The article deals with problems of the commercialization

of scientific and technical activity in construction. The question of

a lack of legislative framework, obliging the practical application of

the results of intellectual activity in the same technology based on

contract procurement system.
Module and functionally-oriented techniques in designing and manufacturing worm gears
Authors: Лагутин Сергей , Lagutin Sergey , Сандлер Александр , Sandler Aleksandr , Гудов Евгений , Gudov Evgeniy
Published: June 2017

Worm gears of different purposes and dimensions belong to those objects of mechanical engineering which are connected with science intensive design works (computations and development of design arrangements) and with their not less science intensive technological realization in the course of production. In 2016 the authors published a training manual “Theory and practice of general worm gears production” (M. Infra-Engineering, 2016. – pp. 346) where there is generalized a scientific-production experience of enterprises of mechanical engineering and machine tools manufacture for the formation of the complex of modular and functionally-oriented technologies ensuring required quality and performance characteristics of such objects. As a distinctive feature of such a complex is the interconnection of design and production processes of gear basic parts: a worm, a worm wheel with similar processes in the formation of a producing surface in a gear-cutting tool for a worm wheel.
Cutting mode impact upon output process parameters at processing of polycrystalline composite materials
Authors: Зубарев Ю. , Zubarev Yu. , Приемышев А. , Priyomyshev A. , Заостровский А. , Zaostrovskiy A.
Published: June 2017

The peculiarities in polymeric composite material cutting are considered. The recommendations for use of different materials for cutters, their geometry and treatment modes are offered that allows obtaining the required quality of a product surface.
Photo-acoustic substance homogenization for optical measurements
Authors: Григорьянц Александр , Grigoryants Aleksandr , Якимова Мария , Yakimova Mariya , Мельников Дмитрий , Melnikov Dmitriy , Садков Андрей , Sadkov Andrey
Published: June 2017

Theoretical and experimental investigations of photo-acoustic effect use for the homogenization of dispersion particles with the purpose of spectral measurement accuracy increase are shown.
DETERMINATION OF DIAGNOSTIC PARAMETERS FOR DIAGNOSIS METHODS WITH TRANSITION FUNCTION
Authors: Ахметзянов  , Akhmetzyanov Ilnur
Published: June 2017

In order to optimize operating costs and more efficient maintenance and repair of automotive engines it is necessary to accurately forecast the technical operation parameters, which is achieved by selection of the correct method of diagnosis. The development of any method of diagnosis involves determining the most informative diagnostic parameters and ranges of their change. To compile the algorithm of in-place diagnosis according to Bayes, it is necessary to identify patterns of change in compression, cyclic flow and air flow, depending on the operating time of the tractor, which conducted statistical studies of tractors MTZ-80/82 fitted with engines D-243 in the agricultural enterprises of the Republic of Tatarstan. The research is to measure compression, power systems, air supply of tractors with different operating time. The dependence of data according to the parameters of the developments was composed, which are presented in a graph. As the intensity of the changes in diagnostic parameters of the engine speed have been chosen, the intensity of the cyclic changes in supply and changes in the intensity of the air flow. The results of development tests of D-243 engine with various kinds of faults were made up. The compression of 2.7 MPa was set for serviceable engine, 2.4 MPa for engine in good condition and 2.1 MPa for a faulty engine, the fuel injection pressure was 18.5 MPa, 16.5 MPa, 15.5 MPa, the discharging in intake manifold at a nominal speed was 2 kPa, 4 kPa and 7 kPa for the respective states of the engine. The carried experimental and theoretical studies allow us to determine not only the dependence of diagnostic parameters from compression, cyclic flow and air flow, but also to establish acceptable ranges of diagnostic parameters, which is the basis of the proposed method of in-place engine diagnostics and serves as a basis in the preparation of diagnostic matrix and establishes rules for the application of solutions.
Anáfora ou repetição em Música: figura e recurso expressivo
Authors: Paschoal Stéfano
Published: June 2017

A base do trabalho que ora se apresenta é a Retórica clássica latina, tal qual apresentada na obra “Rhetorica ad Herennium”, cuja autoria se atribui, ainda que de forma polêmica, a M.T. Cícero. A Retórica clássica latina exerceu grande influência na produção literária e retórica dos séculos posteriores, mais expressivamente durante a Renascença e o século XVII. É interessante notar que não apenas o âmbito literário recebe influências da Retórica, mas também outro, a saber, possuidor de linguagem própria, distinta e autônoma: a música. São profícuos os tratados que buscam demonstrar as relações entre Retórica e Música, afirmando ser a música, mesmo, passível de uma análise retórica. Isto criou o que se pode chamar de “retórica musical”. Apresentaremos aqui um breve panorama sobre Retórica e Música no século XVII alemão e enfatizaremos como se evidenciam em textos musicais diversos a anáfora.

PALAVRAS-CHAVE

Retórica, música, figuras de linguagem.

ABSTRACT

This paper relies on Latin Rhetoric as presented in the book “Rhetorica ad Herennium”. It is interesting to observe that not only literature becomes influenced from Rhetoric, but also another area, which consists itself in a specific and independent language: Music. German 17th century doesn’t receive Rhetoric influences only in the literature, intending – through imitation and emulation in a language policy programme – the formation of a national language and literature, but also in the Music. We will briefly present a panorama about assimilation of rhetoric means in Music during Renaissance and 17th century and emphasize how an important part of elocution – the figures of speech – becomes clear in the “musical” text. In this paper we show how one can find examples of anaphor in two different musical examples.

KEYWORDS

Rhetoric, music, figures of speech.
A Questão da Presença na Filosofia e nas Artes Cênicas
Authors: Ferracini Renato , Feitosa Charles
Published: June 2017

No espetáculo ao vivo o corpo do espectador parece se sintonizar com a distribuição de energia provocada por outros corpos em movimento. Pode-se dizer que o público dança com o performer, sente a vertigem dos movimentos, balança no mesmo ritmo, mesmo sem se movimentar na cadeira. Os recursos técnicos do vídeo, cinema ou computador, ao contrário, fazem com que o senso de esforço do ator ou performer seja distorcido, transmitindo frequentemente uma impressão de espontaneidade em cada gesto. A respiração ofegante, o suor, os erros e os riscos da performance ao vivo acabam por ser eliminados após a edição. A transformação do corpo fluido ao vivo para o corpo exposto na tela passa por uma série de mediações e distanciamentos, que implicam em uma redução das possibilidades de percepção do movimento. O objetivo da mesa é refletir sobre os limites e possibilidades do conceito de “presença cênica” na filosofia, no teatro e nas artes contemporâneas da performance, enfatizando as transformações mediáticas e tecnológicas das relações entre corpo, tempo e espaço, tanto do artista em cena, como dos objetos ao redor, como ainda do público em geral.

ABSTRACT

In the live performance the body of the viewer seems to tune into the energy distribution caused by other moving bodies. It can be said that the public dance with the performer, feel the vertigo of motion, balance at the same pace, even without moving the chair. The technical features of video, film or computer instead distort the sense of the actor's effort, often conveying a spontaneous impression in every gesture. The panting, sweat, errors and risks of live performance end up being eliminated after editing. The transformation of live body fluid to the body exposed on the screen passes through a series of mediations and differences that imply a reduction in perception of movement possibilities. The purpose of the round-table is to reflect on the limits and possibilities of the concept of "stage presence" in philosophy, theater and contemporary arts of performance, emphasizing the media and technological transformation of the relationship between body, space and time, both the artist on the scene as the objects around, but also the general audience.

KEYWORDS

Template, referencing, sources.
Schwierigkeiten und Möglichkeiten einer transformativen Ökonomik
Authors: Beckenbach Frank
Published: June 2017

Die Diskussion um eine neue Wirtschaftswissenschaft ist durch zahlreiche Leerstellen gekennzeichnet. Auf dieser Grundlage werden Hemmnisse, Treiber und mögliche Inhalte einer trans formativen Ökonomik aufgezeigt.
From the Editor in Chief
Authors: Doğanay Ahmet
Published: June 2017

Değerli bilgi üretici ve tüketicileri, Pegem Eğitim ve Öğretim Dergisinin yeni bir sayısıyla herkese merhaba. Eğitim bilimlerinin çeşitli alanlarından, hakem değerlendirme süreci tamamlanan altı değerli çalışmayı yayımlıyoruz bu sayıda. İşbirliği ve katkılarından dolayı değerli yazar ve hakemlerimize teşekkürlerimi sunuyorum. Yaz ve güz ayları tarımda birçok ürünün hasat mevsimidir. Çiftçiler aylarca döktükleri alın terlerinin sonucunu alırlar bu aylarda. Tıpkı çiftçiler gibi akademisyenler de, çalışmaları yayımlandığında alırlar ürünlerini. Bu ürünün maddi bir getirisi olmasa da, sağladığı manevi doyum tartışılamaz. Son günlerde bir biri ardına gerçekleştirilen kongre ve sempozyumlarda sunulan bildiriler makale olarak dergiye ulaşmakta. Ancak değerli hakemlerimizden aynı hızla dönüş maalesef gerçekleşemiyor. Yoğun akademik işler arasında, gelen makaleleri değerlendirmek gerçekten büyük özveri istiyor. Bununla birlikte, hakemlerin katkısı olmadan da bu işler yürümüyor. Bu nedenle, değerli hakemlerimizden özverili katkılarını sunmaya devam etmelerini, tüm yazar ve dergi ekibi adına diliyorum. Bu sayıda sizlerle paylaşmak istediğim bir konu daha var. Kongre ve sempozyumlar bilimsel çalışmaların sunulduğu, paylaşıldığı, tartışıldığı ve eleştirildiği platformlardır. Bildirilerin sunulması için verilen zaman genellikle çok sınırlı olmasına karşın, yine de tartışma ve eleştirel bir ortam yaratılabilmektedir çoğu zaman. Bu tartışma ve eleştiriler, çalışmaların geliştirilmesi için değerli fırsatlar sunmaktadır. Bildirilerin sunulduktan sonra, herhangi bir dergiye gönderilmeden önce, bu eleştiri ve katkılar sonucunda tekrar gözden geçirilmesinde büyük yarar vardır. Bu süreçte, hazırlanan makalelerin alanda uzman bir ya da daha fazla arkadaş tarafından gözden geçirilmesi de, makalenin geliştirilmesine önemli katkılar sağlayacaktır. Unutmamak gerekir ki, bir makalenin niteliği sadece araştırılan konunun önemi ve özelliği ile ilgili değil, nasıl araştırıldığı ve bilimsel ilkelere uygun, ayrıntılı bir şekilde raporlaştırılıp raporlaştırılmadığı ile de ilgilidir. Gelecek sayıda buluşmak dileği ile herkese saygılar sunarım.
Opinions of second grade elementary school students about foreign language teaching by native speaker instructors
Authors: Işigüzel Bahar , Kırmızı Bülent
Published: June 2017

The objective of this study was to determine the opinions of secondary school students regarding the native speaker instructors in the foreign language lesson. The study was conducted in a private secondary school in which especially American and German native speaker instructors' lecture in the foreign language classes. Voluntarily participated in this study 45 students who were attending the sixth and seventh grades in that school. In this study, quantitative and qualitative research approaches were used. The data were collected in the academic year 2009-2010. The quantitative data was collected with a survey that included 12 items which was developed by the researchers of this study. In the qualitative part, an open-ended question was asked to the participants to understand their attitudes towards the native speaker instructors. The results of this study indicated that most of the sixth and seventh grade students of this secondary school have negative attitude to the native speaker instructors in their foreign language lesson. The students stated that their desire to learn a foreign language had decayed in the native speaker instructors classes. Suggestions were made to make teaching-learning process more efficient, effective and live up to student's expectations.
Communication skills of teachers and the effect of emphatic tendency behavior on levels of liking of children
Authors: UĞURLU Celal Teyyar
Published: June 2017

The purpose of this study was to investigate the communication skills of elementary school teachers and the effect of their emphatic tendencies on their levels of liking of children. This study tried to reveal the communication skills of the teachers and how their levels of liking of children affect their emphatic tendencies together and one by one. The population included 2076 teachers who worked at 81 elementary schools in Sivas province in the 2011-2012 academic years. Within the elementary schools, 35 schools were randomly selected. The sample of this study comprised 906 teachers who worked at these schools. Out of the applied scales, 416 actionable scales were evaluated. The data was collected via "Communication Skills Evaluation Scale", "Emphatic Tendency Scale" and "Barnett Liking of Children Scale". It was concluded from the study that the communication skills and emphatic tendencies of the teachers affected their levels of liking of children and communication skills together with the emphatic tendencies increased this effect a little more.
Feasibility analysis of uav in dengue control
Authors: Chiroli Daiane Maria de Genaro , Montilha Murillo Martins , Samed Márcia Marcondes Altimari
Published: June 2017

There are intensifying actions to combat the mosquito Aedes which is admittedly responsible for the transmission of diseases: chikungunya, dengue and zika. Among these dengue is a recurring problem that affects the entire world, especially the tropical areas. It is considered one of the world’s greatest public health problems by the World Health Organization, which estimates that approximately 390 million people get infected by this disease each year worldwide. In Brazil, since the first report of the disease in 80’s, dengue has continually occurred, alternating epidemic periods with peaks of increasing disease. Therefore, this study aims to assess the feasibility of using unmanned aerial vehicle, popularly known as drone, in aid of the dengue control program executed in Maringá - PR. In conclusion the use of this aircraft is feasible, since it is an economically attractive investment due to its low cost against the annual investment with manpower.
Endurance Running Training Individually Guided by HRV in Untrained Women
Authors: da Silva Danilo F. , Ferraro Zachary M. , Adamo Kristi B. , Machado Fabiana A.
Published: June 2017

da Silva, DF, Ferraro, ZM, Adamo, KB, and Machado, FA. Endurance running training individually guided by HRV in untrained women. J Strength Cond Res 33(3): 736–746, 2019—The aim of this study was to analyze the effects of heart rate variability (HRV)-guided training compared with a standardized prescription on (a) time to complete 5-km running performance (t5km), (b) peak treadmill running speed (Vpeak) and its time limit (t
lim at Vpeak), and (c) autonomic cardiac modulation (i.e., parasympathetic activity and recovery) in untrained women. Additionally, we correlated changes in t5km with changes in Vpeak, t
lim at Vpeak and autonomic cardiac modulation. Thirty-six untrained women were divided into a HRV-guided training group (HRVG) and a control group (CG). The CG followed a predefined program, alternating moderate-intensity continuous training (MICT) and high-intensity interval training (HIIT). The determination of MICT or HIIT was based on the pretraining HRV for HRVG. MICT was performed if HRV was <mean − 1 SD of previous measures. Otherwise, HIIT was prescribed. The t5km, Vpeak, t
lim at Vpeak, parasympathetic activity (i.e., rMSSD) and parasympathetic reactivation (i.e., HRR) were measured before and after the training period. The t5km decreased to a greater magnitude in the HRVG (−17.5 ± 5.6% vs. −14 ± 4.7%; Effect Size (ES) between-group difference = moderate). rMSSD and t
lim at Vpeak only improved in HRVG (+23.3 ± 27.8% and +23.6 ± 31.9%, respectively). The HRVG experienced greater improvements in Vpeak and HRR (Vpeak: 10 ± 7.3% vs. 8.2 ± 4.7%; HRR: 19.1 ± 28.1% vs. 12.6 ± 12.9%; ES between-group difference = small). Although HRVG performed less MICT than CG, the volume of MICT was negatively related to changes in t5km. Vpeak changes were highly correlated with t5km changes. The greater improvements in HRVG for t5km and autonomic modulation reinforce the potential application of this tool.
First record of Epidius parvati Benjamin, 2000 (Araneae: Thomisidae) from Pathiramanal Island, India
Authors: Malamel Jobi J. , Ambalaparambil Sudhikumar
Published: June 2017

The thomisid spider Epidius parvati Benjamin, 2000, described from Sri Lanka, is newly recorded from India based on the specimens collected from the Pathiramanal Island, Alappuzha District, Kerala State. A short description and illustrations of both male and female are provided.
Distribution extension of Oriental mayfly Clypeocaenis oligosetosa Soldán, 1983 (Ephemeroptera: Caenidae)
Authors: Martynov Alexander V. , Palatov Dmitry M.
Published: June 2017

Clypeocaenis Soldán, 1978 consists of 7 species, 3 of them are known from the Oriental region. Clypeocaenis oligosetosa Soldán, 1983 was described from Vietnam and until now was known only from 2 localities within this country. We found C. oligosetosa in Thailand for the first time. This record significantly extends the known distribution of the species. The main distinguishing characters of the larvae of C. oligosetosa are illustrated. We observed a few small morphological differences between Thai specimens, investigated paratypes of C. oligosetosa and its original description.
Diversity and distribution of jumping plant-lice (Hemiptera: Psylloidea) along edges of Amazon–Cerrado transitional forests in Sorriso, Mato Grosso, Brazil
Authors: Mazzardo Tatiana , Barreto Marliton R. , Queiroz Dalva L. de , Burckhardt Daniel
Published: June 2017

Little is known about the jumping plant-lice of Brazil from where seven families, 45 genera and 76 species have been previously reported, but estimates suggest that there may be as many as 1,000 species. This study reports 34 species of Psylloidea which were collected along the edges of Amazon–Cerrado natural transitional forests in the municipality of Sorriso, state of Mato Grosso, from August 2013 to July 2014. Of the species reported in this study only nine represent described taxa, two of which are reported for the first time from Mato Grosso.
Validating an adapted questionnaire to determine perceptions of the clinical learning environment
Authors: Kotze Koot , Archer Elize
Published: June 2017

This article was migrated. The article was marked as recommended. IntroductionThe clinical learning environment is a key component of undergraduate medical students' curriculum. At our institution there was a need for an electronic instrument to evaluate student perceptions of their clinical learning environment.MethodologyThe Uppsala Instrument, which had previously been used to improve student perceptions of their clinical learning environments, was adapted for the context of a South African Academic Hospital by a panel of experts and then completed by a group of students. The results were then used to determine the validity and reliability of the instrument using principal component analysis.ResultsThe instrument proved to be highly reliable at measuring a single underlying component, 'perception of the clinical learning environment', and due to this, further determination of validity was limited. The findings were similar to those reached by other authors' studies of instruments evaluating the clinical learning environment in that most variance in responses were attributable to a single component.ConclusionThe fact that the instrument measures the clinical environment as a whole is useful, however it does not allow for deeper analysis of educational constructs within the clinical learning environment.
Evolution of Schengen: an Example of Enhanced Cooperation and Differentiated Integration Model within the Area of Freedom Security and Justice
Authors:   Nicolaus Copernicus University in Toruń (Poland), Piechowicz Michał
Published: June 2017

The Amsterdam Treaty has established the Area of Freedom, Security and Justice (AFSJ). Since then, it is an example of a policy-making area creating its way quickly and comprehensively. However, in this paper the main dilemma is to what extent the Schengen development has modified the framework of AFSJ and how it adapts in this policy while being an example of enhanced cooperation and differentiated integration model. Developments in this area are part of a realisation that European states need to act together to better face new challenges to peace and internal security, while ensuring respect for democracy and human rights. It is important to add, that cooperation in the Area of Freedom Security and Justice has been driven by forces different from that seen in other policy areas.
Freedom is a State of Mind
Authors: Bakker Annet
Published: June 2017

Artwork by Loco, an incarcerated artist at P.I. Neuwegein, The Netherlands.
Daily activity and nest attendance in a breeding pair of Parrot Crossbills Loxia pytyopsittacus in southern Norway
Authors: Steen Ronny , Austad Anne-Marie , Johnny Steen , Bjerke Bjørn Aksel
Published: June 2017

Crossbills Loxia spp. breed during late winter and early spring and feed their nestlings almost exclusively with seeds from conifer cones. In the present paper, we studied a breeding pair of Parrot Crossbills Loxia pytyopsittacus from dawn to dusk in Southern Norway using a time-lapse camera. The study was conducted in the second half of the nestling period, when the nestlings were from 10 to 21 days old and capable of keeping warm without assistance from the female. Almost all recorded parental nest visits involved feeding the nestlings. The average number of feeding visits was about 10 visits per day by each parent and these visits were distributed evenly throughout the day, starting about 30 min after sunrise and ending 60 min before sunset. Parents fed the young regularly at about 1-hour intervals. The female feeding duration was constant throughout the period, whereas the male feeding duration was longer initially, but decreased compared with the female later in the nestling period. In most feeding visits, the male and female arrived at the nest at the same time or shortly after to each other. The probability of parents removing nestlings’ faecal sacs was very high during the early period, but decreased as the nestlings became older. Overall, our use of modern camera monitoring technology enabled a more comprehensive description of a pair of Parrot Crossbill’s daily activity patterns and nest attendance behaviour than previous studies conducted by observations from a hide.
MicroRNAs in veterinary cardiology
Authors: Wolf Marcela , Muehlbauer Eloísa , Sousa Marlos Gonçalves
Published: June 2017

ABSTRACT: The use of biomarkers is an important recent development in veterinary medicine. Biomarkers allow non-invasive quantification of substances with diagnostic and prognostic potential in several diseases. The microRNAs are small, non-coding RNAs that regulate gene expression and are expressed in different forms in many diseases. Reduced or over-expression of microRNAs showed to be part of the pathogenesis of some heart diseases in humans and animals. Diagnostic and therapeutic value of measuring microRNAs in veterinary cardiology is increased because abnormal expression can be managed by the use of antagonists (in the case of overexpression) and mimicking (in the case of underexpression). Thus, this literature review aimed to compile scientific evidence of dysregulation of microRNAs expression in different cardiac diseases being one of the promises in the therapeutic field and diagnosis of veterinary cardiology. MicroRNAs not only have potential as a biomarker but may also help in elucidation of aspects of the pathogenesis of a variety of diseases.
Livro Didático de Geografia: estudo da linguagem cartográfica
Authors: Prado Clodoaldo José Bueno do , Carneiro Sônia Maria Marchiorato
Published: June 2017

Resumo: O artigo objetiva socializar a pesquisa sobre o livro didático de Geografia dos anos finais do ensino fundamental (ciclos III e IV) em relação à linguagem cartográfica. O estudo, qualitativo, avaliou a relação dos textos discursivos e atividades com os mapas, sob o foco da consciência espacial cidadã. O referencial teórico teve como pressupostos: a concepção de uma Educação Geográfica comprometida com a cidadania do educando; e as representações cartográficas nos livros didáticos enquanto instrumentais metodológicos. Os resultados evidenciam que, de maneira geral, a Coleção apresenta os elementos essenciais dos mapas, apesar de ocorrerem ainda incorreções e insuficiências; e a articulação de textos e atividades com mapas é deficiente.
DNA based library prepartion for full-length small ribosomal RNA sequencing on the Illumina MiSeq and HiSeq platforms v1
Authors: M. Karst Søren , Morten S. Dueholm not provided , Simon J. McIlroy not provided , Rasmus H. Kirkegaard not provided , Per H. Nielsen not provided , Mads Albertsen not provided
Published: June 2017

This protocol describes the preparation of Illumina libraries for high through-put sequencing of near full-lengthbacterial 16S rRNA sequences. The method is based on the universal 27F and 1492R primers designed by Lane et al.* Sequences for primers and adaptorused can be found under guidelines. *Lane, D. J. (1991). 16S/23S rRNA sequencing. In E. Stackebrandt & M. Goodfellow (Eds.), Nucleic Acid Techniques in Bacterial Systematics (pp. 115–175). Chichester, United Kingdom: John Wiley and Sons.
Induction of root symbioses in common bean v1
Authors: Nanjareddy Kalpana , Manoj-Kumar Arthikala not provided , Brenda-Mariana Gómez not provided , Lourdes Blanco not provided , Miguel Lara not provided
Published: June 2017

A hallmark of legume plants is their ability to establish mutualistic symbioses with Rhizobium bacteria and arbuscular mycorrhizal fungi (Rhizophagus irregularis). These symbionts help in providing nutritional benefits to the host plants. Herein, we provide a protocol to inoculate the common bean for the induction of symbiont colonization. This protocol has been routinely used in our laboratory with high reproducibility.
Metabolomic analyses for plasma samples v2
Authors: Jove Mariona , Manuel Portero-Otin not provided , Reinald Pamplona not provided
Published: June 2017

Protocol for sample deproteinization before performing non-targeted metabolomics, including metabolite aligment, molecular feature characterization and preliminary annontation using the Agilent proprietary database PCDL
Fraquil Media v1
Authors: Steven Wilhelm Dr.
Published: June 2017

Please contact Dr. Steven Wilhelm (wilhelm@utk.edu) for additional information regarding this protocol.
Fraquil Media v2
Authors: Steven Wilhelm Dr.
Published: June 2017

Please contact Dr. Steven Wilhelm (wilhelm@utk.edu) for additional information regarding this protocol. Adapted from the original publication Morel, F. M. M., J. C. Westall, J. G. Reuter & J. P. Chaplick, 1975. Description of the algal growth media ‘Aquil’ and ‘Fraquil’. Water Quality Laboratory, Ralph Parsons Laboratory for Water Resources and Hydrodynamics, Massachusetts Institute of Technology, Technical Report 16, 33 pp.
Facilitating Intercultural Study through Novel Reading —The Application of Reading Task Journals
Authors: Nie Yanwei
Published: June 2017

As English becomes the global lingua franca, the correlation between the English language and a particular culture is problematic (Baker, 2012). Thus, EFL learners are expected to cultivate their intercultural competence while improving their linguistic competence. There is a growing interest in introducing novel reading to intercultural communication courses, because EFL learners can be exposed to more cultural varieties and understand the culture concepts better by drawing on examples from the novel. However, many EFL learners feel overwhelmed to read due to the reading task difficulty and the lack of guidance about intercultural study. This paper aimed to investigate the effectiveness of applying reading task journals to facilitate students’ intercultural study through novel reading. The research findings indicate that the difficulty of novel reading lies in the cultural aspect and the reading task journals successfully help EFL learners comprehend the novel, raise the awareness of the reading process, improve language skills, undertake intercultural study and enhance intercultural communicative competence in the end.
Theoretical Bases of Training and Social Psychological Support of Persons with Hearing Impairments (with the example of a Course of Study in “Engineering, Technologies and Technical Sciences”)
Authors: Stanevskiy A.G. , Khrapylina L.P.
Published: June 2017

The paper focuses on theoretical issues in developing variations of a model of teaching and individual social psychological support of persons with hearing impairments in the field of Engineering, Technologies and Technical Sciences. The authors emphasize that the variations are based on the generalized outcomes of their long-term research on higher education in students with hearing impairments in the context of inclusive environment. The paper outlines the key elements of the model’s components and analyses the experience in organising educational process for the benefit of individuals with hearing impairments in universities (with the example of the Bauman Moscow State Technical University). It also defines the approaches to choosing the optimal model.

The work was carried out within the State Contract No. 05.R03.11.0001 of August 17, 2016.
Review of In Our Own Hands: Essays in Deaf History 1780-1970
Authors: Portolano Marlana
Published: June 2017

No abstract available.
CRISE DO CAPITALISMO E EDUCAÇÃO: AS ESTRATÉGIAS SOCIAIS-LIBERAIS DE FOCALIZAÇÃO NA POBREZA DOS GOVERNOS “NEODESENVOLVIMENTISTAS”
Authors: Almeida Larissa Martins de , Cunha Kivania Karla Albuquerque
Published: June 2017

O nosso artigo pretende discutir a estratégia engendrada pelo grande capital de focalização na extrema pobreza com vistas a atenuar os antagonismos de classe em tempos de globalização da “questão social”. Para tanto, procura discutir o papel dado a política de educação neste contexto, trazendo ao debate os mecanismos sociais-liberais utilizados pelos governos “neodesenvolvimentistas” para direcionar os investimentos da educação em programas que promovam um investimento em capital humano através da educação básica e profissionalizante e do incentivo ao empreendedorismo.
CARACTERIZAÇÃO DA DIVERSIDADE GENÉTICA EM Alcantarea patriae (BROMELIACEAE) POR MEIO DE MARCADORES MICROSSATÉLITES
Authors: Bernardi Ugo Cesar Sartori , Pereira Aléxia Gonçalves , Manhães Vitor , De Souza Lucimara Cruz , Moro Kelmer Mozer , Rodrigues Vieira Alessandra Abreu , De Miranda Fábio Demolinari
Published: June 2017

A família Bromeliaceae ocorre em sua maioria nas regiões neotropicais destacando se devido ao elevado número de espécies endêmicas. Essa família tem sofrido com o extrativismo ilegal de várias espécies em suas populações naturais, o que promove erosão genética e redução no potencial adaptativo destas populações.  Os marcadores microssatélites são ferramentas úteis e eficientes para estudos de diversidade genética vegetal, entretanto existem espécies para as quais, esses marcadores ainda não foram descritos. Uma forma alternativa de uso é a amplificação heteróloga. No presente estudo, utilizou-se primers desenvolvidos para Pitcairnia geyskesii e para Pitcairnia albiflos em Alcantarea patriae de maneira a estimar a diversidade e a estrutura genética de populações naturais. As análises demostraram a existência de diferenciação genética entre populações amostradas e a subdivisão em dois grupos genéticos, além de indicar baixo fluxo gênico e efeitos de endogamia.
ASPECTOS TEÓRICOS DOS MÉTODOS DIRETO E INDIRETO DE VALORAÇÃO ECONÔMICA DO MEIO AMBIENTE
Authors: Dassie Rangel Fernanda , Fardim Christo Bruno , Silva Trugilho Winny , Mancini Antunes da Silva Gabriel , Gomes da Silva Elaine Cristina
Published: June 2017

A valoração ambiental tem sido um assunto muito discutido por muitos estudiosos atualmente. O objetivo deste trabalho é apresentar e discutir sucintamente os métodos diretos e indiretos de valoração econômica do meio ambiente por meio de revisão de literatura. Para tal, buscou-se informações acerca do conteúdo, construindo assim uma pesquisa exploratória, descritiva e qualitativa. Ao final pôde-se perceber que as opiniões das pessoas e o valor atual de mercado contribuem consideravelmente no processo de valoração e que utilizam direta ou indiretamente um recurso ambiental.
RELAÇÃO DO PERÍODO DE PERMANÊNCIA EM VENTILAÇÃO MECÂNICA INVASIVA COM O GÊNERO E A IDADE DOS PACIENTES DA UTI DO HOSPITAL MUNICIPAL DE RIO VERDE
Authors: Nogueira Leonardo Squinello , Oliveira Millene Leite , De Freitas Filho Nulciene Firmino , De Freitas Filho Getulio Antonio , Cabral Rejane Maria Cruvinel , Dias Roberto , Miranda Lya Carla Manso , Ferreira Katia Silveira , Silva Renata Nascimento , Cabra Fernando Duarte
Published: June 2017

A Insuficiência Respiratória é uma patologia comum dentro de uma Unidade de Terapia Intensiva (UTI), levando os pacientes a necessitarem de Ventilação Pulmonar Mecânica.Essa pesquisa objetiva-se a avaliar o período de permanência em ventilação mecânica invasiva em relação ao gênero e a idade dos pacientes. Trata-se de um estudo cuja amostra foi composta por 50 prontuários, no período de março a maio de 2015 na UTI do Hospital Municipal de Rio Verde. O presente estudo apresentou os seguintes resultados em relação ao gênero dos 50 participantes da pesquisa,não foram encontradas diferenças estatisticamente significativas (P = 0,9184) entre os dois gêneros. no entanto em relação à faixa etária, o presente estudo não obteve alteração estatisticamente significativa entre os grupos,contudo em relação a permanência em VMI demonstrou diferenças estatisticamente significativas (P = 0,0413) entre os grupos 40 a 59 anos e 60 a 80 anos.Conclui-se portanto que não houve diferença no período de ventilação mecânica relacionada ao gênero.
LEVANTAMENTO DE PLANTAS ALIMENTÍCIAS NÃO-CONVENCIONAIS EM CARAGUATATUBA
Authors: Santos Flávia Cristina Ribeiro , Dória Karolina Marie Alix Benedictte Van Sebroeck
Published: June 2017

A maioria das pessoas não tem o conhecimento que as plantas alimentícias não-convencionais (PANC) podem servir de alimento. Pois, de modo geral, são plantas descartadas pelo grande comércio. Este desuso, é sobretudo, devido à falta de informação da sua utilidade e preparo. Há muitas perdas de plantas silvestres que possuem altos valores nutritivos, maiores do que plantas domésticas. O objetivo deste trabalho é realizar o levantamento das espécies de PANC que ocorrem no centro Caraguatatuba-SP. Constatou-se a presença de 13 espécies pertencentes a 11 famílias. A família mais abundante é a Asteraceae com três espécies. As demais contam com apenas uma espécie. A Crespi japonica é a espécie mais comum, sendo encontrada em três das cinco ruas amostradas.
EFEITO DE BACILLUS THURINGIENSIS (BT) SOBRE LAGARTAS DE SPODOPTERA FRUGIPERDA E ANTICARSIA GEMMATALIS EM LABORATÓRIO
Authors: Fernandes Fabrício Oliveira , Martins Liliane Nachtigall , Scheunemann Tiago , Härter Adilson , De Lara Ana Paula Stori , Fialho Gustavo Sessa
Published: June 2017

Anticarsia gemmatalis (lagarta-da-soja) e Spodoptera frugiperda (lagarta-do-cartucho) são insetos polífagos e desfolhadores, responsáveis por prejuízos em diversas culturas. O objetivo deste trabalho é avaliar a mortalidade desses insetos através do consumo de dieta artificial com a adição de cepas de Bacillus thuringiensis (Bt). Para a realização dos experimentos foram utilizadas 30 lagartas de A. gemmatalis (3º instar) e S. frugiperda (1º instar) para cada tratamento, as quais foram acondicionadas em tubos de vidro esterilizados contendo 1 cm3 de dieta artificial. Posteriormente foram adicionadas alíquotas de 150µl de Bt var israelensis (Bti), Bt var kurstaki (Btk), Bt var oswaldo cruz (Bto) e água destilada para o controle. O tratamento com Btk resultou em maior mortalidade ambas espécies, seguidas por Bto para A. gemmatalis e Bti para S. frugiperda.