bluuebunny/crossref_metadata_2025 huggingface dataset:
The impact of demographic changes on HR processes
Authors: Dobre Eleonora Casandra
Published: August 2024

Demography plays a fundamental role in shaping the landscape of human resources. The interdependent relationship between these two fields is observable in the workforce composition, labor market trends, talent management strategies and also on learning. Changes perceived in demographic changes are shaping and transforming human resources management. In an era marked by demographic shifts, technological advancements, and evolving work preferences, organizations are facing the need to understand and adapt to the changing demographics to effectively manage their human resources. This article explores how demography influences HR and offers insights into how organizations can navigate this dynamic landscape with a highlight on learning related processes. The aim is to contribute to human resources specialists as practitioners and academic experts to be able to observe the impact of demographic changes on human resources management. Observations are obtained in a global perspective.
Subsidiarity and proportionality in Public Works’ administration
Authors: Hunyadi Attila Gábor
Published: August 2024

This study intends to identify those levels of public sphere at which the public choice seems to be optimal, according to the principles of subsidiarity and proportionality, and depending on the scale of public works investments and the historical period, legal context. 20th century Transylvania – with an area that could comprise in it twice the Belgium’s and one whole Netherlands – being part consecutively of Austria-Hungary, Romania, Hungary (its Northern part) and again Romania (since 1947 People’s Republic of Romania) is a good terrain to analyze in the long term the specificities of public administration, public-private investments and the efficiency of public works in different time periods on local, regional and country level, continuing with the comparison of cross-border, trans- and international level public works based on public procurement. The durability and warrant of final product as public goods are also an actual topic, mainly because most of these public goods and historic public buildings approach their lifetime limits and need urgent restoration, nowadays their renovation frequently being financed by the local and state authorities with funds from the European Union’s Cohesion or Regional Development Funds. According to a classic Romanian public law and accountability law principle (local-regional) cooperatives had certain facilities in being involved in implementing public works on (local-regional) level without breach in the general law of competition. Based on the local roots of any cooperative and their ideal functioning according to universal principles (democratic structure, delegation of votes, autonomy inside a network or a hierarchical structure with their own supervising and coordinating non-lucrative offices, together with proper financial centers), it was a general rule and many parts in the world it still works as such, except for the neo capitalist oriented former East-Central Europe, where all the preexisting cooperative structures were dismantled and there are no countervailing powers or checks and balances on this market of public works. The historical examples (in a comparative Romanian-Hungarian or Transylvanian Saxon) will surely help in understanding the logic of public procurement policies and investments, works and the efficiency of realizing/ creating public goods.
Can the experience be experienced?
Authors: Tóth Norbert
Published: August 2024

Research on the school performance of Roma students draws attention to the fact that, although a positive trend can be observed in terms of the success of Roma students in the last decade, we cannot see any meaningful progress, the gap has not been reduced between Roma and non-Roma students (Fehérvári 2015). We examined the phenomenon in Tiszabercel, Szabolcs-Szatmár-Bereg county. It is mainly due to the fact that the basic concept of Anthropology of Education is that social mechanisms are situational, so the solution attempt must also be situational (Delamont 2012). Based on the approach and cause-effect relationship of our research, we tried to map the peculiarities of the institution and its pedagogical practice from the point of view of the catch-up of Roma students in the elementary school operating in the settlement from the sociological perspective of education. During the empirical data collection, we used a qualitative research method, in addition to the analysis of school documents, we conducted semi-structured interviews with elementary school teachers (N=10).
Bone microarchitecture and fracture risk in rheumatoid arthritis
Authors: Kozyreva M. V. , Demin N. V. , Dobrovolskaya O. V. , Nikitinskaya O. A. , Toroptsova N. V.
Published: August 2024

BACKGROUND: Microarchitecture of trabecular bone tissue can currently be evaluated using a special program for dual-energy X-ray absorptiometry (DXA) to determine the trabecular bone score (TBS).

   AIM: to assess bone microarchitecture and fracture risk in patients with rheumatoid arthritis (RA).

   MATERIALS AND METHODS: a cross — sectional study included 95 postmenopausal women with confirmed diagnosis of RA (mean age 62.3 ± 8.1 years). The survey was conducted using a specially designed questionnaire, laboratory examination, DXA of the lumbar spine (L1–L4) with the determined of TBS and proximal femur. The risk of major osteoporotic fractures (MOF) was assessed using FRAX calculator without or with TBS standardization.

   RESULTS: 41 (43.2 %) patients had osteoporosis (OP) in at least one measurement area, while in L1–L4 — 26.3 %, in the femoral neck (FN) — 22.1 % and in total hip (TH) — 11.6 % persons. 35.8 % women had normal, 25.3 % — partially degraded and 38.9 % — degraded microarchitecture according to TBS. In patients with a history of fractures, low TBS was detected significantly more often than in people without fractures (p < 0.05). TBS was negatively correlated with age with age (r = -0.30, p = 0.003), duration of postmenopause (r = -0.26, p = 0.014), cumulative dose of glucocorticoids (GCs) (r = -0.34, p = 0.045) and positively correlated with BMD L1-L4 (r = 0.43, p < 0.001), BMD of the FN (r = 0.21, p = 0.038) and BMD TH (r = 0.23, p = 0.02). Normal BMD values in L1–L4 and at the same time degraded microarchitecture according to TBS were in 9.5 % RA persons. A high risk of fractures according to FRAX was detected in 47 (49.5 %) women, and FRAX adjusted for TBS increased the number of such patients to 52 (54.7 %).

   CONCLUSION: OP was diagnosed in 43.2 % of postmenopausal women with confirmed RA, and 38.9 % had degraded bone microarchitecture by TBS. Negative associations were found between TBS and age, duration of postmenopause, cumulative dose of GCs, and positive associations with BMD in all parts of the skeleton. Including TBS values into the FRAX calculator made it possible to redistribute patients into risk groups, as a result of which 54.7 % of patients had a high risk of MOF.
South African new academics’ experiences of precarity: Becoming and unbecoming the condition of coloniality through collective reflexivity
Authors: Daniels Nicole , Hoosen Taahira Goolam , Behari-Leak Kasturi Behari-Leak , Jayakumar Jaisubash
Published: August 2024

The transition into Higher Education can be complex with South African new academics expected to drive institutional change and social transformation. We examine precarity from our situated geopolitical positioning, as a condition of coloniality and neoliberal forces. Our focus on racially marginalised new academics straddling multiple pedagogical roles addresses the challenges of needing to become collective reflexive agents, yet also unbecome conditions of coloniality. Through autoethnography, lived experiences of precarity as affective states are shown to co-produce displaced estrangement, undermine a coherent sense of self, and reinscribe colonial modes of doing and being. We argue that knowledge rooted in African-centred epistemologies offers new academics’ ways to collectively rally together to disrupt the status quo. This approach enriches the minimally understood concept of collective reflexivity. Our findings underscore the value of bringing decolonisation perspectives into conversation with reflexivity theories. We propose collective reflexivity can help new academics navigate their situational challenges.
Exploring an alternative access route to higher education in South Africa: A human development and social justice analysis
Authors: Mkwananzi Faith , Vargas Carmen Martinez
Published: August 2024

Widening access to higher education is one of the key policy priorities for many countries and institutions globally. While the concern has been to increase the number of young people entering university, there has also been interest in the diversity of people entering university, such as women, working students, and those from rural communities. This paper builds on that body of knowledge by combining ideas from the capability approach and social justice to understand what widening access may mean through a human development lens in contexts of historical injustice and inequality. It draws on the University Preparation Programme (UPP) and the Extended Programme (EP) provided by one of the universities in South Africa as a route to expand access and participation for students who might otherwise not access university. In doing so, it presents empirical and theoretical contributions to the multidimensionality of inequalities and how these influence higher education opportunities.
Students’ Use Behaviors of E-Learning Management Systems in Ghanaian Public Universities: What do the demographics say?
Authors: Amadiok Daniel , Abroampa Winston Kwame , Osei Eric Opoku
Published: August 2024

It is crucial to identify and offer intense training to groups of students who underutilize e-learning management systems. This study used a quantitative research methodology to evaluate demographic differences in students' use of e-LMS in Ghanaian public universities. A questionnaire was used to collect data from 531 students. The techniques for data analysis included independent t-tests, mean computation, percentage estimation, and standard deviation estimation. Based on age and educational level, the results showed that there were no statistically significant variations in how students used e-LMSs. Nevertheless, a statistically significant variation in their use behavior with regard to gender and academic major was established. Particularly, social science majors and female students in Ghana's public universities showed low use behavior of e-LMS. Therefore, it is recommended that students majoring in social sciences and those who are female undergo enhanced training on using the e-LMS platform.
Transitioning Hands-On STEM Teacher Training in Ghana from an In-Person to Online Modality
Authors: Hanson Mawuena A. , Beem Heather
Published: August 2024

ABSTRACT
COVID-19 provided an avenue for teaching and learning to be done remotely, hence Organization X took advantage of this to transition from in-person to online training mode. This study aims to determine how the efficacy of hands-on STEM teacher training in Ghana compares between fully in-person and fully online modalities as well as the best practices that can be elucidated from a Ghanaian training provider’s transition from in-person to online modalities. Organization X translated its training content by converting them into videos and PowerPoint Presentations to be accessed both synchronously and asynchronously. 220 teachers who teach Science, Math and ICT were selected from 10 regions. Organization X put measures in place to successfully implement its first online training. Results showed that teachers can be trained online even in low resourced settings. Secondly, using locally available materials enables hands-on, experiential education even in remote areas.
EFL Teaching and Learning in Cameroon: Decolonizing Francophone Teachers’ Minds
Authors: Kouam Clement
Published: August 2024

British Received Pronunciation is the English accent officially recommended for educational practices in Cameroon although research has shown that it is far-fetched even to English language practitioners (Ngefac 2011). While most Anglophone teachers of English now promote the Cameroon English accent in the classroom, Francophone EFL teachers continue to reject it in favour of native varieties. Interestingly, their efforts to sound native instead lead them to hypercorrection. This phenomenon hinders learners’ fluency in English and the English-French bilingualism policy promoted in the country. The study was carried out from Kachru’s (1985) World Englishes framework and Levis’ (2005) Intelligibility Principle. Drawing from an analysis of the curriculum content designed for the training of EFL and ESL professionals and from a careful observation of classroom practices by Anglophone and Francophone teachers, this paper argues that a decolonization of Francophone EFL teachers’ minds and the replacement of Standard British English by mainstream Cameroon English can significantly enhance the EFL teaching/learning process.
Key words: Cameroon, Cameroon English, Received Pronunciation, EFL teaching/learning
AN EVALUATION OF THE EFFICIENCY OF AN EMPLOYER BASED ON THE QUALITY OF WORKING LIFE IN TRANSFORMATION OF THE COMPETITIVE ENVIRONMENT AND THE LABOR SPHERE
Authors: Nikolaev Nikolai ,   Ural State University of Economics
Published: August 2024

This article substantiates the scientific and practical relevance of developing a methodological approach to assessing the effectiveness of an employer's activities based on the indicator of the quality of work-ing life in the transformation in the labor market and the labor sphere associated with the development of an in-formation technology society, and flexible and remote forms of work. The development of the theory and methodology of managing the quality of the working life are consid-ered. The concept of “the quality of working life” is defined, and the category “the efficiency of an employer's activity” is proposed for the first time. A methodical approach has been developed for a comprehensive assessment of the effectiveness of the activity and competitiveness of an employer using indicators of wages, social security, a special assessment of working conditions, the analysis of management documentation, observation, and employee surveys. An indi-cator for assessing the satisfaction of employees with the quality of their working life is proposed. The devel-oped methodological approach makes it possible to assess and improve the quality of the working life of em-ployees, balanced with an increase in the efficiency of the organization. The results of the study can be used to assess and increase the efficiency of employers' activities, the quality of the working life of employees, the development of effective labor relations, and an increase in the efficiency of workers in production and other organizations.
THE COSTS OF SOFTWARE PROJECTS FOR INDUSTRIAL ENTERPRISES
Authors: Ozornin Stanislav ,   Ural Federal University named after B.N. Eltsin, Terlyga Nadezhda ,   Ural Federal University named after B.N. Eltsin
Published: August 2024

There are a number of problems in pricing software projects intended for the industrial sector, in-cluding significant restrictions by developers for Russian industrialists and the experience of Russian IT companies in the development of such projects and establishing prices for them. This indicates the relevance of the research topic and predetermined its goal: to develop a dependence on the cost of a software project considering the charac-teristics of the environment, the authorities, and contractual relations to secure reserves for expenses in unpredicta-ble or poorly predictable conditions. To achieve this goal, the authors analyzed existing approaches to pricing, iden-tified the specifics of software products and industrial enterprises as consumers, and developed a methodological approach to determining prices for a software project. The approach is based on the cost approach and the approach based on Customer Perceived Value Pricing. It includes four interrelated evaluation subsystems, including estab-lishing a price option in connection with risk. The option value is assessed using a combined methodology based on the expert method and the traditional risk components of impact and probability. The use of these parameters al-lows us to obtain a price for a software project, ensuring equal benefits for the developer and the customer.
MARKETING SUPPORT FOR SCALING AN INNOVATIVE STARTUP
Authors: Azoev Gennadiy ,   State University of Management, Sumarokova Ekaterina ,   State University of Management
Published: August 2024

The venture nature of scaling startups requires special attention to commercial risks, which in-crease many times compared to the scaling of innovative products. To minimize such risks, the most effective tools are branding technologies that orient a startup to maximize profits by increasing the number of consumers, developing and implementing relevant strategies and competition tools, and increasing the marginality of the product. This article highlights the risk zones of scaling innovative startups and a structured formula for the de-pendence of startup profits on market capacity, market share, and profitability, taking into account the specif-ics of innovation and innovative products to minimize these risks. If the startup does not pass filtering for mar-ket capacity, target market share, and planned profitability, and does not reach the target profit which could be obtained as a result of scaling, then the project is postponed. For projects that pass filtering for these three key profit multipliers, marketing methods and technologies for increasing them are proposed with planned results for each event, the timing of their implementation, and the necessary budget. The set of proposals can be a marketing basis for scaling business plans, the elements of which are pre-sented using the example of innovative Russian products.
PEMODELAN JUMLAH KASUS PNEUMONIA PADA BALITA DI JAWA TIMUR MENGGUNAKAN METODE REGRESI POISSON INVERSE GAUSSIAN DILENGKAPI GUI-R
Authors: Utami Krisdiana Nur , Sugito Sugito , Santoso Rukun
Published: August 2024

Reducing toddler mortality is one of the desire of sustainable development programs.Modeling count data may be analyzed the usage of Poisson regression.The assumption that must be met in Poisson regression is that the mean and variance values must be equal, often in count data there is a violation of this assumption. This is indicated by the variance value which is greater than the mean value (overdispersion). Poisson Inverse Gaussian (PIG) regression is one form of mixed Poisson regression to model data that experience overdispersion cases. The MLE method is used to estimate the PIG regression parameters and hypothesis testing using the MLTR method. The best model of the PIG regression form is based on the smallest AIC value. The results of hypothesis testing concluded that the percentage of under-fives who received exclusive breast feeding had a significant effect on the number of pneumonia cases among toddler. Data modeling using the PIG regression method in this study is complemented by the creation of a Graphical User Interface (GUI) that can facilitate the process of selecting the best model.
Prospek Potensial Mikroalga Sebagai Biofuel Di Kepulauan Riau Guna Mewujudkan Net Zero Emission
Authors: Natasha Febiana , Hutajulu Ezra Solafide , Pardi Hilfi
Published: August 2024

Kepulauan Riau memiliki kondisi lingkungan yang ideal serta memiliki iklim tropis yang hangat untuk budidaya mikroalga. Mikroalga merupakan salah satu dari sumber daya laut yang masih belum dimanfaatkan di daerah ini meskipun mempunyai keunggulan dari berbagai macam bidang, terutama biofuel. Penelitian ini bertujuan untuk mengidentifikasi besarnya prospek pemanfaatan mikroalga di Kepulauan Riau sebagai biofuel. Metode yang digunakan adalah metode kajian literatur sistematis. Ada tiga tahapan dalam penggunaan metode ini, yakni tahap perencanaan, tahap tinjauan dan tahap melaporkan hasil. Hasil penelitian menunjukkan bahwa ada 8 jenis mikroalga yang dapat dikembangkan sebagai biofuel di Kepulauan Riau, yakni Chlorella, Spirulina, Spirogyra, Scenedesmus, Nitzschia, Navicula, Anabaena, dan Microcystis. Prospek pemanfaatannya relatif besar dikarenakan keanekaragaman hayati yang didukung oleh iklim tropis yang cocok untuk dilakukan budidaya mikroalga. Selain itu, garis pantai yang panjang juga dapat mendukung budidaya mikroalga secara besar-besaran. Sayangnya, masih memiliki keterbatasan dalam hal teknologi dan infrastruktur pembangunan biofuel ini. Oleh karenanya, diperlukan dukungan dan komitmen pemerintah dalam pembiayaan dan investasi industri biofuel agar terwujudnya Net Zero Emission di Indonesia, terutama Kepulauan Riau.
Synthesis and Antibacterial Activity Test of Dibutyl Tin (IV) N-Ethylbenzyl Dithiocarbamate Compound Against Salmonella Thy.Atcc.14028 and Propionibacterium acnes Bacteria
Authors: Sanuddin Mukhlis , Andriani Medi , Angraini Tiara
Published: August 2024

The complex compound dithiocarbamate exhibits various biological activities, including anticancer, antibacterial, antifungal, and antioxidant properties. Dibutyl tin (IV) N-ethyl benzyl dithiocarbamate was synthesized to overview its structure and evaluate its antibacterial activity against Salmonella typhimurium ATCC 14028 and Propionibacterium acnes. This compound was synthesized via an in situ method by adding dibutyl tin (IV) dichloride, N-ethylbenzylamine, and carbon disulfide, forming a precipitate, which was then dried to yield a white powder. This powder can also be crystallized. The compound was characterized using FTIR, 1H NMR, and 13C NMR spectroscopy, along with antibacterial activity testing using the disc diffusion method. The FTIR analysis revealed characteristic absorption bands at 1111.00 cm-1 (C-N), 731.02 cm-1 (C-S), 2954.95 cm-1 (C-H), 1602.85 cm-1 (C=C), 360.69 cm-1 (Sn-S), and 567.07 cm-1 (Sn-C). The 1H NMR spectrum showed chemical shifts at 0-3.8570 ppm (δ CH3), 5.0032-5.1472 ppm (δ N-CH2), and 7.2780-7.3607 ppm (δ C6H5). The 13C NMR spectrum displayed signals at 0-34.5610 ppm (δ CH3), 48.6398-56.9247 ppm (δ N-CH2), 127.6651-135.7665 ppm (δ C6H5), and 201.7568 ppm (δ CS2). The antibacterial activity of dibutyl tin (IV) N-ethyl benzyl dithiocarbamate was assessed, revealing inhibition zones against Salmonella typhi of 6.78 mm (100 ppm), 7.36 mm (120 ppm), and 7.76 mm (140 ppm), categorizing the activity as moderate. Against Propionibacterium acnes, inhibition zones were 1.8 mm (100 ppm), 1.88 mm (120 ppm), and 2.13 mm (140 ppm), categorizing the activity as weak. Based on these findings, it can be concluded that dibutyl tin (IV) N-ethyl benzyl dithiocarbamate can be synthesized to form an octahedral structure and exhibits antibacterial activity. However, it is not yet suitable for use as a new antibiotic.
Development and validation of a stability indicating UPLC-DAD method coupled with MS-TQD for ramipril and thymoquinone in bioactive SNEDDS with in silico toxicity analysis of ramipril degradation products
Authors: Elzayat Ehab M. , Sherif Abdelrahman Y. , Shahba Ahmad Abdul-Wahhab , Kazi Mohsin , Alyahya Mohammed , Darwish Hany W.
Published: August 2024

The identification of degradation products of therapeutic molecules in pharmaceutical formulations has gained significant attention due to their potential impact on patient safety. Ramipril (RP), an antihypertensive agent, was incorporated into a self-nanoemulsifying drug delivery system (SNEDDS), which greatly enhanced its bioavailability. However, none of the previous studies have investigated the toxicological effects of these degradation products that may form during storage. Moreover, a bioactive SNEDDS containing black cumin oil (BCO) and its bioactive ingredient, thymoquinone (TQ), was used to further enhance the therapeutic activity of RP. To assess the stability of the proposed formulation, a validated ultrahigh-performance liquid chromatography (UPLC) method was developed to simultaneously measure the concentrations of RP and TQ. The formulation was subjected to accelerated stress conditions to facilitate drug degradation. The resulting degradation products were analyzed using mass spectroscopy (MS) to determine their molecular mass, and their chemical structures were in silico predicted using Zeneth Nexus software, while their toxicity was assessed using in silico Derek Nexus software. RP and TQ, along with their degradation products, were separated using an HSS T3 column at a flow rate of 0.25 mL/min. The detection wavelengths for RP and TQ were 210 and 254 nm, respectively. The developed UPLC method exhibited acceptable linearity for both RP and TQ, with correlation coefficient (r
2) values exceeding 0.9995 and 0.9998, respectively. The method provided accurate, precise, and high-resolution analysis of both drugs and their degradation products within a short run time of less than 3.2 min. The toxicity and mutagenicity of two alkaline degradation products of RP were predicted using in silico software Derek Nexus (version 6.3). Several toxicity endpoints, including chromosomal damage, skin sensitization, and hepatotoxicity, were predicted. Overall, the developed method can be used to evaluate the stability and integrity of RP and TQ during the development of the proposed antihypertensive formulation.
Oligometastatic disease – a renaissance for surgery?
Authors: Goetze Thorsten , Chevallay Mickael , Dosch Michel , Marcelis Jordan , Al-Batran Salah-Eddin , Mönig Stefan Paul
Published: August 2024

Half of the patients with esophageal cancer, cancer of the gastro-esophageal junction and gastric cancer present metastasis at the time of diagnosis. In addition, even patients originally thought to be free of metastasis will present metachronous metastasis in the course of the disease. These patients are considered incurable and current standard of care for metastatic esophageal, gastro-esophageal junction and gastric cancers is a systemic therapy without curative intention. However, patients presenting only a low metastatic load are now defined as oligometastatic disease and should benefit from an aggressive, multimodal therapy. We present here a review of recent publications investigating multimodal therapies for oligometastatic disease and showing that a systemic therapy combined with a resection of the primary tumor together with metastasis is associated with a better prognosis than a systemic therapy alone. We also give a precise focus on esophageal squamous cell carcinomas and adenocarcinomas of the gastro-esophageal junction and of the stomach. Interestingly, patients with oligometastatic cancer of the esophago-gastric junction can even be treated in curative intention with such a multimodal therapy as we present here in a short case report. In conclusion, new therapeutic strategies including multimodal approaches for oligometastatic disease have shown promising results in the last years and ongoing randomized prospective trials will provide us the evidence to include them in future European guidelines.
Recurrence relations for the joint distribution of the sum and maximum of independent random variables
Authors: Efrem Christos N.
Published: August 2024

In this paper, the joint distribution of the sum and maximum of independent, not necessarily identically distributed, nonnegative random variables is studied for two cases: (i) continuous and (ii) discrete random variables. First, a recursive formula of the joint cumulative distribution function (CDF) is derived in both cases. Then recurrence relations of the joint probability density function (PDF) and the joint probability mass function (PMF) are given in the former and the latter case, respectively. Interestingly, there is a fundamental difference between the joint PDF and PMF. The proofs are simple and mainly based on the following tools from calculus and discrete mathematics: differentiation under the integral sign (also known as Leibniz’s integral rule), the law of total probability, and mathematical induction. In addition, this work generalizes previous results in the literature, and finally presents several extensions of the methodology.
Language attitudes in the mass media: What attitude towards the Ukrainian language was formed by the Odesa media (2014–2023)
Authors: Kuznietsova Tetiana
Published: August 2024

The article examines the issue of the representation of language attitudes in mass media texts. The focus is on the attitude towards the Ukrainian language manifested in the texts of Odesa online publications during 2014–2023. Content analysis of the popular internet publications of Odesa has been chosen as the main method of research. We focused on mass media materials that mentioned the concepts of “The Ukrainian language” and “The Russian language”. More than 700 media texts were analyzed in total. The research enabled us to identify the main models of attitudes towards the Ukrainian language in the analyzed media through the dichotomy of ‘ours – theirs’, which changed both in intensity and content. Conditionally, we can identify the date of the change in this dichotomy as the beginning of the large-scale invasion of Russia into Ukraine. During 2014–2021, a trend of ambivalent attitudes. After February 24, 2022, the language-based dichotomy ‘ours – theirs’ has changed its expressive power and clearly fixed its objects: as a rule, the Ukrainian language has become ‘ours’, whilst Russian – ‘theirs’. This, in its turn, has led to the displacement of negative evaluation rhetoric regarding the Ukrainian language in all the analyzed media. It was due to the political situation in the country and the change in many values of Ukrainians during the war.
Fotografias arrebatadas do inferno para imaginar o inimaginável
Authors: Michelon Francisca Ferreira
Published: August 2024

Fotografias arrebatadas do inferno para imaginar o inimaginável
O patrimônio cultural imaterial no país de Viollet-le –Duc Sucesso e insucessos da Convenção da UNESCO para a salvaguarda do patrimônio cultural imaterial
Authors: Hottin Christian
Published: August 2024

Como em vários países da Europa, as políticas patrimoniais na França estãomarcadas pela anterioridade e preeminência do patrimônio imaterial. A aplicaçãoda Convenção da UNESCO para a salvaguarda do patrimônio cultural imaterialcoloca, nesse contexto, diversos problemas que são analisados nesse artigo. Qualadministração se encarregará dessa nova política ? Quais comunidades identificarem um país marcado pela tradição do Estado Nação?Como elaborar projetos decandidaturas considerando que os procedimentos estabelecidos pela Unescoparecem em constante evolução? Quatro anos após a ratificação, a política dopatrimônio se implanta progressivamente na França : ela possui a aceitação decomunidades e coletividades e a atenção crítica dos pesquisadores mas conviveainda com as reticências da administração cultural.
Os projectos de urbanismo comercial e a revitalização do centro da cidade
Authors: Fernandes José V. Rio
Published: August 2024

A relação entre comércio e cidade perde-se na história. É tambémmuito antiga a ligação do comércio com o planeamento e a intervençãourbanística. Todavia, nas últimas décadas, com a concentração empresarial queocorreu na oferta, o aumento e diversificação do consumo e o acréscimosignificativo da dimensão e número de shoppings e outras formas comerciais, oestudo, planeamento e intervenção sobre esta relação conheceu um novoimpulso.É sobre a acção realizada sobre a ligação entre o espaço urbano e actividadecomercial, dito urbanismo comercial e sobre o caso português em particularpara os anos 80 e 90 que o presente texto trata, dando conta da forma como aintegração europeia e o financiamento público ajudou a criar uma novaimagem dos centros das cidades portuguesas. A reflexão, partindo da avaliaçãopossível, alarga-se aos desafios que hoje se colocam às relações entre a áreacentral das cidades e a actividade retalhista.Palavras-chave: espaço urbano, comércio, patrimônio.
O patrimônio industrial no Reino Unido: contexto, paisagem, territórios
Authors: Edelblutte Simon
Published: August 2024

Esse artigo apresenta em um primeiro momento a evolução da noçãode patrimônio industrial no Reino Unido, país de nascimento da indústria,colocando-a em um contexto europeu e mundial. Utilizando a análise depaisagem, estuda-se em seguida os diferentes tipos de preservaçãopatrimonial: integral no interior dos museus ou mesmo parques temáticos,indireta quando o sitio industrial é preservado mas reutilizado para outrasfunções (residência, comércio,etc…). Finalmente se aborda a expansão recenteda noção e territórios do patrimônio industrial que incluem hoje, para além dafábrica, a paisagem industrial em seu conjunto tal qual havia sido criada pelaatividade industrial em seu apogeu.Palavras-chave: patrimônio, indústria, Reino Unido.
Stem Cell Therapy for SARS-CoV-2 and Influenza Virus Infections
Authors: Datta Neelabh
Published: August 2024

The emergence of infectious diseases, including viral zoonoses, has allowed intensive research into novel therapeutic approaches. Stem cell therapy, mostly using mesenchymal stem cells (MSCs), has garnered significant attention due to the immunomodulatory properties and tissue repair capabilities. MSCs have demonstrated promise in treating severe COVID-19 cases and several clinical trials have revealed that MSC therapy improves 28-day survival rates, reduces mortality, and accelerates recovery. These cells effectively mitigate a cytokine storm, relieve pulmonary symptoms, and positively influence organ recovery, including the liver and kidneys. Bioanalytical readings return to normal following MSC administration, emphasizing the potential in managing COVID-19-induced complications. MSC therapy offers a potential solution for infection with the influenza virus, which is responsible for historical pandemics and epidemics, and remains a global health concern. MSCs inhibit immune cell-mediated responses and reduce lung damage in animal models, and despite antiviral drugs, influenza-induced manifestations persist. MSCs, with an ability to counteract inflammation and promote lung tissue repair, hold promise for managing influenza infections. While MSCs offer therapeutic benefits, certain challenges remain. Specifically, ethical considerations, regulatory hurdles, and scalability are some of the challenges that hinder widespread adoption. However, ongoing systematic reviews and meta-analyses provide real-time insight that support the security and effectiveness of MSC therapy.
Cardiac Magnetic Resonance Visualization of the Myocardial Microstructure in Non-Ischemic Cardiomyopathies
Authors: Tang Yun , Ma Xuan , Dong Zhixiang , Chen Xingrui , Yang Shujuan , Chen Xiuyu , Yang Kai , Zhao Shihua
Published: August 2024

Cardiac magnetic resonance (CMR), a non-radiation based type of examination, can achieve the simultaneous comprehensive multi-parameter, multi-plane, and multi-sequence evaluation of the anatomical structure of the heart; and at the same time, determine systolic and diastolic function, and blood perfusion and tissue characteristics. Traditional late gadolinium enhancement imaging based on CMR reflects focal replacement fibrosis, in contrast to normal myocardial signal intensity, but cannot effectively identify diffuse myocardial fibrosis. T1 mapping and its derived extracellular volume fraction can be used to quantitatively analyze the extracellular space in myocardial tissue and evaluate diffuse myocardial interstitial fibrosis that is invisible to the naked eye. Diffusion tensor imaging reveals the direction of cardiomyocyte aggregates by quantifying the anisotropy of water molecule diffusion, and can be applied to evaluate the integrity of myocardial tissue and arrangement structure of myocardial microstructural characteristics. On the basis of the micro-motion of myocardial tissue, feature tracking analysis decomposes myocardial deformation into three dimensions of micro-mechanical changes, and can identify early systolic and diastolic dysfunction before heart enlargement or ejection fraction reduction. This Commentary discusses current research advances in these new techniques, as well as their clinical application prospects and limitations for non-ischemic cardiomyopathies.
Disrupting Racism and Global Exclusion in Academic Publishing: Recommendations and Resources for Authors, Reviewers, and Editors
Authors: Ledgerwood Alison , Lawson Katherine M. , Kraus Michael W. , Vollhardt Johanna Ray , Remedios Jessica D. , Westberg Dulce Wilkinson , Uskul Ayse K. , Adetula Adeyemi , Leach Colin Wayne , Martinez Joel E. , Naumann Laura P. , Reddy Geetha , Chucky Tate Charlotte , Todd Andrew R. , Weltzien Katherine , Buchanan NiCole , González Roberto , Montilla Doble L. James , Romero-Canyas Rainer , Westgate Erin , Zou Linda X.
Published: August 2024

Scholars have been working through multiple avenues to address longstanding and entrenched patterns of global and racial exclusion in psychology and academia more generally. As part of the Society for Personality and Social Psychology’s efforts to enhance inclusive excellence in its journals, the Anti Colorism/Eurocentrism in Methods and Practices (ACEMAP) task force worked to develop recommendations and resources to counteract racism and global exclusion in standard publication practices. In this paper, the task force describes a structure and process we developed for conducting committee work that centers marginalized perspectives while mitigating cultural taxation. We then describe our recommendations and openly accessible resources (e.g., resources for inclusive reviewing practices, writing about constraints on generalizability, drafting a globally inclusive demographic information survey, inclusive citation practices, and improving representation among editorial gatekeeping positions; recommendations and resource links are provided in Table 3). These recommendations and resources are both (a) tailored for a particular set of journals at a particular time and (b) useful as a foundation that can be continually adapted and improved for other journals and going forward. This paper provides concrete plans for readers looking to enhance inclusive excellence in their committee work, authorship, reviewing, and/or editing.
Sketching Musical Meaning? Case Studies from Ligeti’s Late Works
Authors: Donaldson James
Published: August 2024

This article explores how a composer’s working materials can contribute to the analysis of musical meaning. Using examples of Ligeti’s sketches for his late works, I demonstrate how they can support familiar interpretations as well as catalyzing novel understandings. In particular, Ligeti’s prose notes, or “jottings” provide a jumping off point for hermeneutic analysis. Although the sheer amount of information provided in the jottings can be paralyzing, I explore how the material can nevertheless, when used cautiously, contribute insights.

I draw upon Foucault’s distinction between author-function and historical figure to frame two possible roles for the sketch materials. In my first two case studies, I frame the sketches as reflecting the author-function by amplifying a grotesque aesthetic associated with Ligeti’s late works. Examining manipulations of a hunt topic in the sketches for the Hamburg Concerto and of a specific Hungarian folk melody across the two versions of the Violin Concerto, I show how the composer consciously distorted conventional musical topics to produce a distanced or ironic effect. In my third and fourth case studies, I explore the sketches as records of the historical figure of Ligeti. I outline two problematic cases in which his preliminary notes or jottings are at odds with his public pronouncements: the opening of “Spectra” from Ligeti’s Hamburg Concerto, and passages of the Piano Concerto. Tensions between sketch evidence and published remarks lead me to explore the underlying ideologies of Ligeti’s avant-garde aesthetic.
The Role of Sembung (Blumea balsamifera) Leaf Extract in Preventing Atherosclerosis in Hyperlipidemia Rat Models
Authors: I Made Jawi  , I Wayan Putu Sutirta Yasa  , I Gede Widhiantara  , Anak Agung Ngurah Subawa  , Putu Angga Wiradana  , Naw Sin War
Published: August 2024

This study aims to prove that administering BBLE as a natural antioxidant can prevent atherosclerosis by maintaining lipid profiles, antioxidant enzymes, and netrin-1 levels in hyperlipidemia in rat models. The research subjects were 20 adult male Wistar rats (Rattus norvegicus), which were divided into 2 groups using a randomized pretest and posttest control group design. Before treatment and after treatment for 3 months, lipid profiles, MDA, SOD, and netrin-1  were examined. The control group was only given high-cholesterol diets (HCD), while the treatment, apart from HCD, was also given BBLE 4mg/day. The data obtained was tested using paired t-test and group t-test. The results of the study showed that there was a significant decrease in netrin-1 in the control group (p<0.05) after being given HCD for three months. In the treatment group, it also decreased but it was not significant (p>0.05). Netrin-1 levels in the treatment group were higher than the control (p<0.05). The lipid profile experienced a significant increase in HDL in the treatment group accompanied by a significant decrease in MDA and an increase in SOD (p<0.05) when compared with the control group. This study concludes that administering BBLE at a dose of 4 mg/day to rats given HCD caused an increase in netrin-1 levels accompanied by improvements in lipid profiles and prevention of oxidative stress. The findings of this study reveal the novelty of BBLE in treating and maintaining blood vessel function in mice given HCD by increasing netrin-1 levels.
TELLERMAN EXPERIMENTAL FORESTRY OF THE INSTITUTE OF FOREST SCIENCE, RUSSIAN ACADEMY OF SCIENCES: 80-YEAR POLYGON OF STATIONARY BIOCENOTIC STUDIES
Authors: Уткина И.А. , Рубцов В.В.
Published: August 2024

Теллермановское опытное лесничество Института лесоведения РАН, расположенное на юго-востоке Воронежской области, создано по инициативе академика В. Н. Сукачева в 1944 г. как место проведения комплексных долгосрочных исследований в широколиственных лесах на границе между лесостепью и степью. За почти 80-летний период на его территории работали специалисты разного профиля: лесоводы, геоботаники, почвоведы, зоологи, микробиологи, энтомологи, фитопатологи. Были проведены обширные исследования гидрологии массива и водного режима насаждений, средообразующей роли леса, определены запасы фитомассы, продуктивность древостоев в разных типах леса, заложен цикл лесоводственных экспериментов. Всестороннее изучение биогеоценозов включало также изучение корневых систем, фенологические, геоботанические, зоологические, энтомологические, микробиологические и микологические исследования. Разработаны научные основы для создания культур дуба черешчатого (Quercus roburL.) в лесостепи, учитывающие его формовое разнообразие и результаты лесоводственных экспериментов, заложенных в первые десятилетия существования лесничества. Изучение лесохозяйственных аспектов деградации дубовых древостоев позволило разработать практические методы воспроизводства дубрав на вырубках древостоев, смешанных с дубом, посевом желудей с сокращенным периодом рубок ухода.

The Tellerman experimental forestry of the Institute of Forest Science, Russian Academy of Sciences, located in the southeast of Voronezh Oblast, has a long history. It was established on the initiative of Academician V. N. Sukachev in 1944 as a place to conduct complex long-term studies in broad-leaved forests on the border between forest-steppe and steppe. For almost 80 years specialists of different profiles worked in the territory of the forest area: foresters, geobotanists, soil scientists, zoologists, microbiologists, entomologists, phytopathologists. Extensive studies was carried out on the hydrology of the massif and water regime of stands, the environment-forming role of the forest, phytomass reserves were determined, productivity of stands in different forest types was determined, and a cycle of silvicultural experiments was established. The comprehensive study of biogeocenoses also included root systems, phenological, geobotanical, zoological, entomological, microbiological and mycological studies. The scientific basis for the establishment of pedunculate oak (Quercus roburL.) crops in the forest-steppe was developed, taking into account its form diversity and the results of silvicultural experiments laid down in the first decades of the forest region’s existence. The study of silvicultural aspects of oak stands degradation allowed us to develop practical methods of reproduction of oak forests on clear cuts of stands mixed with oak by sowing acorns with a shortened period of thinning.
Bio-preparation of CuO@ZnO nanocomposite via spent mushroom substrate and its application against Candida albicans with molecular docking study
Authors: Abada Emad , Galal Tarek M. , Alhejely Amani , Mohammad Abeer Mahmoud , Alruwaili Yasir , Almuhayawi Mohammed S. , Shater Abdel-Rahman M. , Alruhaili Mohammed H. , Selim Samy
Published: August 2024

Green routes for the bio-designing of bicomponent nanocomposites and their utilizations have attracted many investigators. Bio-designing of CuO@ZnO nanocomposites was performed using spent mushroom substrate (SMS). Ultraviolet-spectrophotometry, transmission electron microscopy, Fourier transform infrared (FT-IR), and energy dispersive X-ray (EDX), besides X-ray diffraction (XRD) were exploited to characterize the synthesized CuO@ZnO. The dimensions of CuO@ZnO nanocomposites ranged from 31.4 and 95.9 nm. Both FT-IR and EDX analyses displayed the presence of some organic constituents from the SMS that joined to the surface of the fabricated CuO@ZnO nanocomposite. CuO@ZnO nanocomposite succeeded in inhibiting Candida albicans with an inhibition zone of 33.5 ± 2 mm. C. albicans biofilm was affected by CuO@ZnO nanocomposite with biofilm inhibition of 25.08, 68.70, and 88.56% at 25, 50, and 75% of minimum inhibitory concentration, respectively. Molecular docking studies showed substantial binding affinities, as well as common hydrogen bonds. Optimum binding sites for CuO and ZnO nanoparticles were found to have binding affinities of interactions with 4YDE, 3DRA, and 1EAG proteins of C. albicans, resulting in, respectively, -2.7942, -3.30097, and -2.52129 kcal/mol, and -3.78244, -4.6029, and -4.1352 kcal/mol values. The findings suggest that CuO@ZnO nanocomposite can effectively suppress C. albicans growth.
When trees become art – wood carving in Romania
Authors: Stanciu Magdalena-Cristina , Bercu Elena , Teacă Carmen-Alice
Published: August 2024

Trees represent a cherished treasure for each nation. They provide a living, soulful, and earthly material, wood, which most often survives millennia and embellishes our everyday life. Wood can be transformed into valuable pieces of art under skilled hands and tools through carving. In Romania, wood is omnipresent in each milepost of people’s life journey from birth to death. It becomes a true and empathic companion of both happy and sad events. Wood teaches us to focus on the present moment and to let go of stressful thoughts and feelings. It is a real valuable “good” in our life.