bluuebunny/crossref_metadata_2025 huggingface dataset:
Link prediction in dynamic networks using random dot product graphs
Authors: Sanna Passino Francesco , Bertiger Anna S. , Neil Joshua C. , Heard Nicholas A.
Published: August 2021

The problem of predicting links in large networks is an important task in a variety of practical applications, including social sciences, biology and computer security. In this paper, statistical techniques for link prediction based on the popular random dot product graph model are carefully presented, analysed and extended to dynamic settings. Motivated by a practical application in cyber-security, this paper demonstrates that random dot product graphs not only represent a powerful tool for inferring differences between multiple networks, but are also efficient for prediction purposes and for understanding the temporal evolution of the network. The probabilities of links are obtained by fusing information at two stages: spectral methods provide estimates of latent positions for each node, and time series models are used to capture temporal dynamics. In this way, traditional link prediction methods, usually based on decompositions of the entire network adjacency matrix, are extended using temporal information. The methods presented in this article are applied to a number of simulated and real-world graphs, showing promising results.
Stick or Carrot? Asymmetric Responses to Vehicle Registration Taxes in Norway
Authors: Ciccone Alice , Soldani Emilia
Published: August 2021

Vehicle registrations have been shown to strongly react to tax reforms aimed at reducing CO﻿2 emissions from passengers’ cars, but are the effects equally strong for positive and negative tax changes? The literature on asymmetric reactions to price and tax changes has documented asymmetries for everyday goods but has not yet considered durables. We leverage multiple vehicle registration tax (VRT) reforms in Norway and estimate their impact on within car-model substitutions. We estimate stronger effects for cars receiving tax cuts and rebates than for those affected by tax increases. The corresponding estimated elasticity is − 1.99 for VRT decreases and 0.77 for increases. As consumers may also substitute across car models, our estimates represent a lower bound.
Measuring the unseen: mobilizing citizen scientists to monitor groundwater in Nepal
Authors: Prajapati Rajaram , Talchabhadel Rocky , Thapa Bhesh Raj , Upadhyay Surabhi , Thapa Amber Bahadur , Ertis Brandon , Davids Jeffrey C.
Published: August 2021

Groundwater-level monitoring provides crucial information on the nature and status of aquifers and their response to stressors like climate change, groundwater extraction, and land use changes. Therefore, the development of a spatially distributed long-term monitoring network is indispensable for sustainable groundwater resource management. Despite being one of our greatest unseen resources, groundwater systems are too often poorly understood, ineffectively managed, and unsustainably used. This study investigates the feasibility of establishing a groundwater monitoring network mobilizing citizen scientists. We established a network of 45 shallow monitoring wells in the Kathmandu Valley using existing wells. We recruited 75% of the citizen scientists through personal connections and the rest through outreach programs at academic institutes and site visits. We used various methods to encourage citizen scientists to complete regular measurements and solicited feedback from them based on their experiences. Citizen scientists were more consistent during the monsoon season (June through September) than non-monsoon seasons. The depth-to-water below the ground surface varied from − 0.11 m (negative sign represents a groundwater level higher than the ground surface) to 11.5 m, with a mean of 4.07 m and standard deviation of 2.63 m. Groundwater levels began to rise abruptly with the onset of monsoon season and the shallowest and the deepest groundwater levels were recorded in peak rainfall months and dry months respectively. Citizen science-based groundwater monitoring using existing wells would be an economic and sustainable approach for groundwater monitoring. Improved groundwater-level data will provide essential information for understanding the shallow groundwater system of the valley, which will assist concerned authorities in planning and formulating evidence-based policy on sustainable groundwater management.
Non-empirical problems in fair machine learning
Authors: Scantamburlo Teresa
Published: August 2021

The problem of fair machine learning has drawn much attention over the last few years and the bulk of offered solutions are, in principle, empirical. However, algorithmic fairness also raises important conceptual issues that would fail to be addressed if one relies entirely on empirical considerations. Herein, I will argue that the current debate has developed an empirical framework that has brought important contributions to the development of algorithmic decision-making, such as new techniques to discover and prevent discrimination, additional assessment criteria, and analyses of the interaction between fairness and predictive accuracy. However, the same framework has also suggested higher-order issues regarding the translation of fairness into metrics and quantifiable trade-offs. Although the (empirical) tools which have been developed so far are essential to address discrimination encoded in data and algorithms, their integration into society elicits key (conceptual) questions such as: What kind of assumptions and decisions underlies the empirical framework? How do the results of the empirical approach penetrate public debate? What kind of reflection and deliberation should stakeholders have over available fairness metrics? I will outline the empirical approach to fair machine learning, i.e. how the problem is framed and addressed, and suggest that there are important non-empirical issues that should be tackled. While this work will focus on the problem of algorithmic fairness, the lesson can extend to other conceptual problems in the analysis of algorithmic decision-making such as privacy and explainability.
High-precision photometry with Ariel
Authors: Szabó Gyula M. , Kálmán Szilárd , Pribulla Theodor , Claret Antonio , Mugnai Lorenzo V. , Pascale Enzo , Waltham Dave , Borsato Luca , Garai Zoltán , Szabó Róbert
Published: August 2021

In this paper we describe the photometry instruments of Ariel, consisting of the VISPhot, FGS1 and FGS2 photometers in the visual and mid-IR wavelength. These photometers have their own cadence, which can be independent from each other and the cadence of the spectral instruments. Ariel will be capable to do high cadence and high precision photometry in independent bands. There is also a possibility for synthetic Jsynth, Hsynth, and wide-band thermal infrared photometry from spectroscopic data. Although the cadence of the synthetic bands will be identical to that of the spectrographs, the precision of synthetic photometry in the suggested synthetic bands will be at least as precise as the optical data. We present the accuracy of these instruments. We also review selected fields of new science which will be opened up by the possibility of high cadence multiband space photometry, including stellar rotation, spin-orbit misalignment, orbital precession, planetary rotation and oblateness, tidal distortions, rings, and moons.
The impact of carbon disclosure mandates on emissions and financial operating performance
Authors: Downar Benedikt , Ernstberger Jürgen , Reichelstein Stefan , Schwenen Sebastian , Zaklan Aleksandar
Published: August 2021

We examine the impact of a disclosure mandate for greenhouse gas emissions on firms’ subsequent emission levels and financial operating performance. For UK-incorporated listed firms a carbon disclosure mandate was adopted in 2013. Our difference-in-differences design shows that firms affected by the mandate reduced their emissions by about 8% relative to a control group of European firms. At the same time, our tests indicate that the treated firms experienced no significant changes in their gross margins. Taken together, our findings indicate that the reporting mandate had a real effect on the variable to be disclosed without adversely affecting the financial operating performance of the treated firms.
Experimental evidence on the effect of incentives and domain in risk aversion and discounting tasks
Authors: Mentzakis Emmanouil , Sadeh Jana
Published: August 2021

Environmental policy evaluation is often criticised for employing discount rates that have little grounding in research. Yet, experimental research aimed at eliciting realistic rates will inevitably require strong assumptions of external validity, while also placing large cognitive demands on subjects by processing tasks of increased unfamiliarity. We use a controlled lab experiment to test the impact of incentives on risk aversion and discounting tasks for monetary and environmental goods. We find that, on average, incentives have little effect on risk aversion or discounting tasks in either domain. Exploring heterogeneity by treatment and socio-demographics some significant patterns emerge. Further, contrary to past work, we find evidence of domain (monetaryvs. environmental good) effects in both risk and discounting.
The explanatory power of citations: a new approach to unpacking impact in science
Authors: Rüdiger Matthias Sebastian , Antons David , Salge Torsten-Oliver
Published: August 2021

Citation analysis has been applied to map the landscape of scientific disciplines and to assess the impact of publications. However, it is limited in that it assumes all citations to be of equal weight. Doing away with this assumption could make such studies even more insightful. Current developments in this regard focus on the evaluation of the syntactic and semantic qualities of the text that surrounds citations. Still lacking, however, are computational techniques to unpack the thematic context in which citations appear. It is against this backdrop that we propose a text clustering approach to derive contextual aspects of individual citations and the relationship between cited and citing work in an automated and scalable fashion. The method reveals a focal publication’s absorption and use within the scientific community. It can also facilitate impact assessments at all levels. In addition to analyzing individual publications, the method can also be extended to creating impact profiles for authors, institutions, disciplines, and regions. We illustrate our results based on a large corpus of full-text articles from the field of Information systems (IS) with the help of exemplary visualizations. In addition, we provide a case study, the scientific impact of the Technology acceptance model. This way, we not only show the usefulness of our method in comparison to existing techniques but also enhance the understanding of the field by providing an in-depth analysis of the absorption of a key IS theoretical base.
Points of convergence between logical empiricism and inductive metaphysics: Hans Reichenbach and Erich Becher in comparison
Authors: Seide Ansgar
Published: August 2021

In this paper, I take a closer look at Hans Reichenbach’s relation to metaphysics and work out some interesting parallels between his account and that of the proponents of inductive metaphysics, a tradition that emerged in the mid- and late 19th century and the early 20th century in Germany. It is in particular Hans Reichenbach’s conception of the relation between the natural sciences and metaphysics, as displayed in his treatment of the question of the existence of the external world, that shows some very interesting similarities with inductive metaphysics. By a comparison with the position of the inductive metaphysician Erich Becher and his handling of the problem of realism, I work out the parallels between Reichenbach’s program and inductive metaphysics. I come to the conclusion that while there are certainly some respects in which Reichenbach’s logical empiricism is closer to the positions of the representatives of the Vienna Circle, it turns out that with regard to his views on metaphysics there is a greater affinity with the program of inductive metaphysics.
Surfactant screening to generate strong foam with formation water and crude oil
Authors: Memon Muhammad Khan , Elraies Khaled Abdalla , Al-Mossawy Mohammed Idrees Ali
Published: August 2021

Most of the available commercial surfactants precipitate due to the hardness of formation water. The study of surfactant generated foam and its stability is very complex due to its multifaceted pattern and common physicochemical properties. This research involved the study of foam generation by using the blended surfactants and their evaluation in terms of enhanced oil recovery (EOR). The objective of this study is to systematic screening of surfactants based on their capability to produce stable foam in the presence of two different categories of crude oil. Surfactant types such as non-ionic, anionic and amphoteric were selected for the experimental study. The foam was generated with crude oil, and the synthetic brine water of 34,107 ppm used as formation water. Surfactant concentration with the both types of crude oil, foam decay, liquid drainage and foam longevity was investigated by measuring the generated foam volume above the liquid level. The surfactant with concentration of 0.6wt%AOSC14-16, 1.2wt%AOSC14-16, 0.6wt%AOSC14-16 + 0.6wt%TX100 and 0.6wt%AOSC14-16 + 0.6wt%LMDO resulted in the maximum foam longevity with formation water and two categories of crude oil. The 50% liquid drainage and foam decay of surfactant solutions with concentration of 0.6wt%AOSC14-16 + 0.6wt%LMDO and 0.6wt%AOSC14-16 + 0.6wt%TX100 were noted with the maximum time. The findings of this research demonstrated that the generated foam and its longevity is dependent on the type of surfactant either individual or blended with their concentration. The blend of surfactant solution combines excellent foam properties.
Thyroid function in the subacute phase of traumatic brain injury: a potential predictor of post-traumatic neurological and functional outcomes
Authors: Mele C. , Pagano L. , Franciotta D. , Caputo M. , Nardone A. , Aimaretti G. , Marzullo P. , Pingue V.
Published: August 2021

Purpose

That thyroid hormones exert pleiotropic effects and have a contributory role in triggering seizures in patients with traumatic brain injury (TBI) can be hypothesized. We aimed at investigating thyroid function tests as prognostic factors of the development of seizures and of functional outcome in TBI.

Methods

This retrospective study enrolled 243 adult patients with a diagnosis of mild-to-severe TBI, consecutively admitted to our rehabilitation unit for a 6-month neurorehabilitation program. Data on occurrence of seizures, brain imaging, injury characteristics, associated neurosurgical procedures, neurologic and functional assessments, and death during hospitalization were collected at baseline, during the workup and on discharge. Thyroid function tests (serum TSH, fT4, and fT3 levels) were performed upon admission to neurorehabilitation.

Results

Serum fT3 levels were positively associated with an increased risk of late post-traumatic seizures (LPTS) in post-TBI patients independent of age, sex and TBI severity (OR = 1.85, CI 95% 1.22–2.61, p < 0.01). Measured at admission, fT3 values higher than 2.76 pg/mL discriminated patients with late post-traumatic seizures from those without, with a sensitivity of 74.2% and a specificity of 60.9%. Independently from the presence of post-traumatic epilepsy and TBI severity, increasing TSH levels and decreasing fT3 levels were associated with worse neurological and functional outcome, as well as with higher risk of mortality within 6 months from the TBI event.

Conclusions

Serum fT3 levels assessed in the subacute phase post-TBI are associated with neurological and functional outcome as well as with the risk of seizure occurrence. Further studies are needed to investigate the mechanisms underlying these associations.
Improved fuzzy clustering for image segmentation based on a low-rank prior
Authors: Zhang Xiaofeng , Wang Hua , Zhang Yan , Gao Xin , Wang Gang , Zhang Caiming
Published: August 2021

Image segmentation is a basic problem in medical image analysis and useful for disease diagnosis. However, the complexity of medical images makes image segmentation difficult. In recent decades, fuzzy clustering algorithms have been preferred due to their simplicity and efficiency. However, they are sensitive to noise. To solve this problem, many algorithms using non-local information have been proposed, which perform well but are inefficient. This paper proposes an improved fuzzy clustering algorithm utilizing nonlocal self-similarity and a low-rank prior for image segmentation. Firstly, cluster centers are initialized based on peak detection. Then, a pixel correlation model between corresponding pixels is constructed, and similar pixel sets are retrieved. To improve efficiency and robustness, the proposed algorithm uses a novel objective function combining non-local information and a low-rank prior. Experiments on synthetic images and medical images illustrate that the algorithm can improve efficiency greatly while achieving satisfactory results.
The Positivity Imperative in Youth Education as a Form of Cruel Optimism
Authors: Brunila Kristiina , Vainio Saara , Toiviainen Sanna
Published: August 2021

In this paper, we revisit the persistent positivity imperative in Finnish youth education by analysing findings from an on-going research project related to various educational interventions targeted at young people ‘at risk’. The article is focused on youth education as an emblematic manifestation of therapeutic ethos and neoliberalism. These manifestations are part of the emergence of the Nordic therapeutic welfare state where neoliberalisation and therapisation have formed alliances in aiming to produce resilient citizens while the relationship between the state and citizenship (as well as rights and obligations that citizenship carries) has changed. In terms of youth education, as a rationality of governing, the alliance between therapisation and neoliberalism results in the creation of suitably resilient, self-responsible, anxious, uncertain and inherently psycho- emotionally vulnerable young people.
Problematizing Law, Rights, and Childhood in Israel/Palestine
Authors: Viterbo Hedi
Published: August 2021

In this book, Hedi Viterbo radically challenges our picture of law, human rights, and childhood, both in and beyond the Israel/Palestine context. He reveals how Israel, rather than disregarding international law and children's rights, has used them to hone and legitimize its violence against Palestinians. He exposes the human rights community's complicity in this situation, due to its problematic assumptions about childhood, its uncritical embrace of international law, and its recurring emulation of Israel's security discourse. He examines how, and to what effect, both the state and its critics manufacture, shape, and weaponize the categories 'child' and 'adult.' Bridging disciplinary divides, Viterbo analyzes hundreds of previously unexamined sources, many of which are not publicly available. Bold, sophisticated, and informative, Problematizing Law, Rights, and Childhood in Israel/Palestine provides unique insights into the ever-tightening relationship between law, children's rights, and state violence, at both the local and global levels.
Explorations in Latin Literature
Authors: Feeney Denis , Hinds Stephen
Published: August 2021

Denis Feeney is one of the most distinguished scholars of Latin literature and Roman culture in the world of the last half-century. These two volumes conveniently collect and present afresh all his major papers, covering a wide range of topics and interests. Ancient epic is a major focus, followed by Latin lyric, historiography and elegy. Ancient literary criticism and the technology of the book are recurrent themes. Many papers address the problems of literary responses to religion and ritual, with an interdisciplinary methodology drawing on comparative anthropology and religion. The transition from Republic to Empire and the emergence of the Augustan principate form the background to the majority of the papers, and the question of how literary texts are to be read in historical context is addressed throughout. All quotations from ancient and modern languages have now been translated and Stephen Hinds has contributed a foreword.
Galois Theory and Its Algebraic Background
Authors: Garling D. J. H.
Published: August 2021

Galois Theory, the theory of polynomial equations and their solutions, is one of the most fascinating and beautiful subjects of pure mathematics. Using group theory and field theory, it provides a complete answer to the problem of the solubility of polynomial equations by radicals: that is, determining when and how a polynomial equation can be solved by repeatedly extracting roots using elementary algebraic operations. This textbook contains a fully detailed account of Galois Theory and the algebra that it needs and is suitable both for those following a course of lectures and the independent reader (who is assumed to have no previous knowledge of Galois Theory). The second edition has been significantly revised and re-ordered; the first part develops the basic algebra that is needed, and the second a comprehensive account of Galois Theory. There are applications to ruler-and- compass constructions, and to the solution of classical mathematical problems of ancient times. There are new exercises throughout, and carefully-selected examples will help the reader develop a clear understanding of the mathematical theory.
The Cambridge Greek Lexicon
Authors: Faculty of Classics, University of Cambridge  , Diggle James
Published: August 2021

The Cambridge Greek Lexicon is based upon principles differing from those of existing Greek lexica. Entries are organised according to meaning, with a view to showing the developing senses of words and the relationships between those senses. Other contextual and explanatory information, all expressed in contemporary English, is included, such as the typical circumstances in which a word may be used, thus giving fresh insights into aspects of Greek language and culture. The editors have systematically re-examined the source material (including that which has been discovered since the end of the nineteenth century) and have made use of the most recent textual and philological scholarship. The Lexicon, which has been twenty years in the making, is written by an editorial team based in the Faculty of Classics in Cambridge, consisting of Professor James Diggle (Editor-in-Chief), Dr Bruce Fraser, Dr Patrick James, Dr Oliver Simkin, Dr Anne Thompson, and Mr Simon Westripp.
A Set of Six
Authors: Conrad Joseph , Knowles Owen
Published: August 2021

A Set of Six (1908) is one of Conrad's most versatile and varied compositions, embracing diverse interests and settings, multiple tonal qualities and a medley of short-story forms (ranging from the novella in 'The Duel' to the anecdotal tale in 'The Informer'). The volume's wide-ranging introduction offers a careful evaluation of the origins and sources of the individual stories, while also measuring their early reception as a published collection. Explanatory notes clarify literary and historical references, identify real-life places and people, and indicate borrowings and Gallicisms. The lengthy textual essay and its accompanying apparatus lay out the history of composition and publication, detailing interventions made by Conrad's typists, compositors and editors. Also included are appendices, allowing the reader first-hand access to Conrad's source material; glossaries of nautical and foreign terms; and illustrations in the form of maps and reproductions of early drafts. By returning to (and respecting) Conrad's own early manuscript and typescript forms, this edition presents the collection and its preface in a form more authoritative than any so far printed.
The state of antibiotic stewardship programs in 2021: The perspective of an experienced steward
Authors: Barlam Tamar F.
Published: August 2021

Recognition of antibiotic stewardship programs (ASPs) as essential components of quality health care has dramatically increased in the past decade. The value of ASPs has been further reinforced during the coronavirus disease 2019 (COVID-19) pandemic because these programs were instrumental in monitoring antibiotic use, assessing emerging COVID-19 therapies, and coordinating implementation of monoclonal antibody infusions and vaccinations. ASPs are now required across hospital settings as a condition of participation for the Centers for Medicare and Medicaid Services and for accreditation by The Joint Commission. In the 2019 National Healthcare Safety Network annual survey, almost 89% of hospitals met the Seven Core Elements for ASPs defined by the Centers for Disease Control and Prevention. More than 61% of programs were co-led by physicians and pharmacists, evidence of the leadership role of both groups. ASPs employ many strategies to improve prescribing. Core interventions of preauthorization for targeted antibiotics, prospective audit and feedback, and development of local treatment guidelines have been supplemented with numerous emerging strategies. Diagnostic stewardship, optimizing duration of therapy, promoting appropriate conversion from intravenous to oral therapy, monitoring at transitions of care and hospital discharge, implementing stewardship initiatives in the outpatient setting, and increasing use of telemedicine are approaches being adopted across hospital settings. As a core function for medical facilities, ASP leaders must ensure that antibiotic use and ASP interventions promote optimal and equitable care. The urgency of success becomes progressively greater as complex patterns of antibiotic resistance continue to emerge, exacerbated by unpredictable factors such as a worldwide pandemic.
Fano-type surfaces with large cyclic automorphisms
Authors: Moraga Joaquín
Published: August 2021

We give a characterisation of Fano-type surfaces with large cyclic automorphisms. As an application, we give a characterisation of Kawamata log terminal$3$-fold singularities with large class groups of rank at least$2$.
Who gets treated for influenza: A surveillance study from the US Food and Drug Administration’s Sentinel System
Authors: Cocoros Noelle M. , Haug Nicole , Cosgrove Austin , Panozzo Catherine A. , Sorbello Alfred , Francis Henry , Garcia Crystal , Orr Robert , Toh Sengwee , Dutcher Sarah K. , Measer Gregory T.
Published: August 2021

Objective:

We describe the baseline characteristics and complications of individuals with influenza in the US FDA’s Sentinel System by antiviral treatment timing.

Design:

Retrospective cohort design.

Patients:

Individuals aged ≥6 months with outpatient diagnoses of influenza in June 2014–July 2017, 3 influenza seasons.

Methods:

We identified the comorbidities, vaccination history, influenza testing, and outpatient antiviral dispensings of individuals with influenza using administrative claims data from 13 data partners including the Centers for Medicare and Medicaid Services, integrated delivery systems, and commercial health plans. We assessed complications within 30 days: hospitalization, oxygen use, mechanical ventilation, critical care, ECMO, and death.

Results:

There were 1,090,333 influenza diagnoses in 2014–2015; 1,005,240 in 2016–2017; and 578,548 in 2017–2018. Between 49% and 55% of patients were dispensed outpatient treatment within 5 days. In all periods >80% of treated individuals received treatment on the day of diagnosis. Those treated on days 1–5 after diagnosis had higher prevalences of diabetes, chronic obstructive pulmonary disease, asthma, and obesity compared to those treated on the day of diagnosis or not treated at all. They also had higher rates of hospitalization, oxygen use, and critical care. In 2014–2015, among those aged ≥65 years, the rates of hospitalization were 45 per 1,000 diagnoses among those treated on day 0; 74 per 1,000 among those treated on days 1–5; and 50 per 1,000 among those who were untreated.

Conclusions:

In a large, national analysis, approximately half of people diagnosed with influenza in the outpatient setting were treated with antiviral medications. Delays in outpatient dispensed treatment were associated with higher prevalence of comorbidities and higher rates of complication.
Local vortex line topology and geometry in turbulence
Authors: Sharma Bajrang , Das Rishita , Girimaji Sharath S.
Published: August 2021

The local streamline topology classification method of Chong et al. (Phys. Fluids A: Fluid Dyn., vol. 2, no. 5, 1990, pp. 765–777) is adapted and extended to describe the geometry of infinitesimal vortex lines. Direct numerical simulation (DNS) data of forced isotropic turbulence reveals that the joint probability density function (p.d.f.) of the second (

$q_\omega$

) and third (

$r_\omega$

) normalized invariants of the vorticity gradient tensor asymptotes to a self-similar bell shape for

$Re_\lambda > 200$

. The same p.d.f. shape is also seen at the late stages of breakdown of a Taylor–Green vortex suggesting the universality of the bell-shaped p.d.f. form in turbulent flows. Additionally, vortex reconnection from different initial configurations is examined. The local topology and geometry of the reconnection bridge is shown to be nearly identical in all cases considered in this work. Overall, topological characterization of the vorticity field provides a useful analytical basis for examining vorticity dynamics in turbulence and other fluid flows.
The association of pre-pregnancy BMI on leptin, ghrelin, adiponectin and insulin-like growth factor-1 in breast milk: a case–control study
Authors: Tekin Guler Tugce , Koc Nevra , Kara Uzun Aysun , Fisunoglu Mehmet
Published: August 2021

The nutrient composition of breast milk alters during lactation, and maternal BMI adds more intricacy into its complexity. We aimed to compare leptin, ghrelin, adiponectin and insulin-like growth factor-1 (IGF-1) levels of pre-feed and post-feed breast milk in mothers with obesity and normal weight, and tried to determine their effects on infants’ growth over weight for length z-score. Twenty obese and twenty normal weight mothers with 2-month-old infants were enrolled in this case–control study. Five millilitre pre-feed breast milk and 5 ml post-feed breast milk were collected. Breast milk leptin, ghrelin, adiponectin and IGF-1 were measured by commercial kits. The pre-feed breast milk of mothers with obesity had significantly higher levels of ghrelin than mothers with normal weight (P = 0·025), whereas the post-feed breast milk of mothers with normal weight had higher levels of adiponectin than the mothers with obesity (P = 0·010). No significant differences were observed in leptin and IGF-1 levels between the two groups. Post-feed breast milk IGF-1 levels of mothers with obesity were correlated with infant’s weight for length z-score at 2 months (r −0·476; P = 0·034). In linear regression models, parity affected the ghrelin in pre-feed breast milk (P = 0·025). Our results revealed that maternal pre-pregnancy BMI was associated with breast milk components.
The Prisoner of War and the Eighteenth-Century Prison
Authors: McGowen Randall
Published: August 2021

Britain and France were at war with each other for over half of the long eighteenth century. This period of sustained conflict produced immense changes, in both countries, in the character of the state and the course of economic development. Yet one of the most obvious ways in which contemporaries would have encountered the war was in the presence of large numbers of prisoners of war held by their country. Early in the century there were thousands of such captives, and by its end they numbered in the tens of thousands. Renaud Morieux takes this neglected topic for the focus of his multifaceted study. These prisoners created challenges that were legal and diplomatic, as well as administrative and financial. The citizens of each country found themselves having to learn to live with captives of a nation with which they were at war. In a work that is both theoretically informed and exhaustively researched, Morieux offers fresh insight into the consequences of war for European society.
Regulating Innovation for Financial Inclusion: Lessons from Nigeria
Authors: Ezechukwu Nwanneka Victoria
Published: August 2021

Innovative services such as mobile payments are potentially transformative because they can increase access to financial services, especially in developing countries. However, such innovations can disrupt the financial services ecosystem, prompting regulators to respond in different ways. These regulatory responses often have a significant impact on the success of such innovative services. Using Nigeria's regulatory approach as a case study, this article highlights specific lessons that should inform future attempts at regulating mobile payments.
Five subtypes of benign paroxysmal positional vertigo
Authors: Ichijo H
Published: August 2021

Background

Benign paroxysmal positional vertigo is classified into five subtypes according to the features of positional nystagmus: lateral canalolithiasis, lateral light cupula, lateral heavy cupula, posterior canalolithiasis and posterior heavy cupula.

Objectives

The first aim of the study was to clarify whether the lateral canal type or posterior canal type was more common. The second aim of the study was to assess the aetiology of benign paroxysmal positional vertigo by investigating the onset time of each subtype.

Methods

The subjects were 512 consecutive patients with benign paroxysmal positional vertigo. The patients were prospectively aggregated, and interviews were used to evaluate onset time.

Results

The lateral canal type (55.5 per cent) was more common than the posterior canal type (44.5 per cent). Time of awakening was the most common onset time in every subtype.

Conclusion

The incidence of lateral canal type is higher than that of posterior canal type. The aetiology of benign paroxysmal positional vertigo is closely related to sleep.
Osteoclastic activity in chronic otitis media with cholesteatoma-related bone destruction
Authors: Özgür A , Yemiş T , Başbulut E , Turgut N F , Özdemir D , Akgül G , Mehel D M , Çelebi M
Published: August 2021

Background

Cholesteatoma-related bone destruction is the cause of many complications due to chronic otitis media. This study aimed to evaluate osteoclastic activity in cholesteatoma-related bone destruction using tartrate-resistant acid phosphatase 5b, an enzyme specific to osteoclastic activity.

Method

Seventy-two patients diagnosed with chronic otitis media were included in this study and were divided into two groups: with and without bone destruction. The blood serum and tissue tartrate-resistant acid phosphatase 5b levels from both groups were compared.

Results

There were no significant differences in the level of serum enzymes between both groups. However, in tissue samples, tartrate-resistant acid phosphatase 5b levels were significantly lower in the bone destruction group than the group without bone destruction.

Conclusion

This study determined that the level of tartrate-resistant acid phosphatase 5b, a specific enzyme for osteoclastic activity in cholesteatoma-related bone destruction, is locally decreased. This data suggests that osteoclastic activity may decrease in cholesteatoma-related bone destruction. However, further experimental and clinical studies are required to clarify this highly complex mechanism.
Electron energization during merging of self-magnetized, high-beta, laser-produced plasmas
Authors: Fiksel G. , Fox W. , Rosenberg M.J. , Schaeffer D.B. , Matteucci J. , Bhattacharjee A.
Published: August 2021

Electron energization during merging of magnetized plasmas is studied using the OMEGA and OMEGA EP laser facilities by colliding two plasma plumes, each containing a Biermann-battery self-generated magnetic field. Two neighbouring plasma plumes are produced by intense laser beams, and the anti-parallel Biermann fields merge and reconnect in the process of the plumes’ expansion and collision. To isolate the merging as an acceleration source, the electron energy spectra obtained from two-plume collision shots are compared with the spectra from single-plume shots. Single-plume shots exhibit an energized electron tail with energies up to

${\sim }250\ \textrm {keV}$

. The electrons in merging experiments are additionally accelerated by

${\sim }50\text {--}100$

keV compared to single-plume shots.
Ainard of Dives and the Ste-Catherine-du-Mont office for St Katherine of Alexandria: ‘Inter praecipuos cantores scientia musicae artis’
Authors: BLASINA JAMES J.
Published: August 2021

Orderic Vitalis writes that Ainard, a monk of Ste-Catherine-du-Mont monastery, composed a historia for St Katherine of Alexandria for use at his institution, which possessed the saint's oil-secreting finger bones. Through a series of historiographical errors, throughout the twentieth century it came to be believed either that Ainard composed not a liturgical office, but a prose vita of the saint, or that the office he had composed was lost. This article presents a survey of the oldest extant offices for St Katherine, showing that the office widely disseminated in German-speaking lands can be traced to Normandy, and through palaeographical and codicological analysis of its earliest source, Paris, Bibliothèque nationale de France, nouv. acq. lat. 1083, to Ste-Catherine-du-Mont in the late eleventh century. The office contained in this manuscript juxtaposes newly composed proper chants for St Katherine with existing chants from a variety of liturgical sources that honoured established saints, and emphasises the power of St Katherine's relics. The contents and themes of the office suggest an agenda of legitimisation and cultic publicity on the part of its creator, which would be consistent with the aims of a monk of Ste-Catherine. If this manuscript is indeed from Ste-Catherine-du-Mont, it likely records the office that Ainard composed. This attribution is reinforced by a textual-melodic style and modal organisation that grounds it in a later style of chant composition, which Ainard – a south German by birth – would likely have been familiar with.
Cardiac echocardiogram findings of severe acute respiratory syndrome coronavirus-2-associated multi-system inflammatory syndrome in children
Authors: Harahsheh Ashraf S. , Krishnan Anita , DeBiasi Roberta L. , Olivieri Laura J. , Spurney Christopher , Donofrio Mary T. , Cross Russell R. , Sharron Matthew P. , Frank Lowell H. , Berul Charles I. , Christopher Adam , Dham Niti , Srinivasalu Hemalatha , Ronis Tova , Smith Karen L. , Kline Jaclyn N. , Parikh Kavita , Wessel David , Bost James E. , Litt Sarah , Austin Ashley , Zhang Jing , Sable Craig A.
Published: August 2021

Background:

A novel paediatric disease, multi-system inflammatory syndrome in children, has emerged during the 2019 coronavirus disease pandemic.

Objectives:

To describe the short-term evolution of cardiac complications and associated risk factors in patients with multi-system inflammatory syndrome in children.

Methods:

Retrospective single-centre study of confirmed multi-system inflammatory syndrome in children treated from 29 March, 2020 to 1 September, 2020. Cardiac complications during the acute phase were defined as decreased systolic function, coronary artery abnormalities, pericardial effusion, or mitral and/or tricuspid valve regurgitation. Patients with or without cardiac complications were compared with chi-square, Fisher’s exact, and Wilcoxon rank sum.

Results:

Thirty-nine children with median (interquartile range) age 7.8 (3.6–12.7) years were included. Nineteen (49%) patients developed cardiac complications including systolic dysfunction (33%), valvular regurgitation (31%), coronary artery abnormalities (18%), and pericardial effusion (5%). At the time of the most recent follow-up, at a median (interquartile range) of 49 (26–61) days, cardiac complications resolved in 16/19 (84%) patients. Two patients had persistent mild systolic dysfunction and one patient had persistent coronary artery abnormality. Children with cardiac complications were more likely to have higher N-terminal B-type natriuretic peptide (p = 0.01), higher white blood cell count (p = 0.01), higher neutrophil count (p = 0.02), severe lymphopenia (p = 0.05), use of milrinone (p = 0.03), and intensive care requirement (p = 0.04).

Conclusion:

Patients with multi-system inflammatory syndrome in children had a high rate of cardiac complications in the acute phase, with associated inflammatory markers. Although cardiac complications resolved in 84% of patients, further long-term studies are needed to assess if the cardiac abnormalities (transient or persistent) are associated with major cardiac events.
Spontaneous thrombosis of the arterial duct in a newborn with alloimmune thrombocytopaenia
Authors: Mingas Odete , Noronha Natália , Sousa Graça , Anjos Rui
Published: August 2021

We present an uncommon challenging case of spontaneous thrombosis of the arterial duct and with alloimmune thrombocytopaenia in a full-term newborn who presented with respiratory distress, hypoglycaemia dispersed petechiae on the trunk, and significant haemorrhage of the umbilical venous catheter.
An extremely rare association of coarctation of aorta with double chambered right ventricle: double-trouble causing bi-ventricular failure in a child
Authors: Arvind Balaji , Ramakrishnan Sivasubramanian , Devagourou Velayoudam
Published: August 2021

Double chambered right ventricle is a rare cardiac defect characterised by an obstructive hypertrophied muscle bundle in the right ventricle. The common associated lesions are ventricular septal defect followed by sub-aortic membrane. We report a child who had coarctation of aorta in association with double chambered right ventricle. This case is being reported for its rarity and challenges in management.
An echocardiographic finding mimicking tricuspid atresia in a neonate with dilated cardiomyopathy
Authors: Takajo Daiji , Gupta Pooja , Aggarwal Sanjeev
Published: August 2021

We report a neonate with dilated cardiomyopathy and have echocardiographic findings consistent with “functional” tricuspid atresia. There was an echo-bright, plate-like tissue at the tricuspid valve position with no forward flow across it. This report underscores the role of right ventricle intracavitary haemodynamic influence on the tricuspid valve leaflet excursion and demonstrates a phenomenon of “pseudo or functional tricuspid atresia” mimicking tricuspid atresia in a patient with acute presentation of cardiomyopathy.
The use of a second language enhances the neural efficiency of inhibitory control: An ERP study
Authors: Kałamała Patrycja , Walther Jonas , Zhang Haoyun , Diaz Michele , Senderecka Magdalena , Wodniecka Zofia
Published: August 2021

This study investigated how natural language use influences inhibition in language-unbalanced bilinguals. We experimentally induced natural patterns of language use (as proposed by the Adaptive Control Hypothesis) and assessed their cognitive after-effects in a group of 32 Polish–English bilinguals. Each participant took part in a series of three language games involving real conversation. Each game was followed by two inhibition tasks (stop-signal task and Stroop task). The manipulation of language use in the form of language games did not affect the behavioural measures, but it did affect ERPs. Performance of the inhibition tasks was accompanied by a reduction of P3 and the N450 amplitude differences after games involving the use of L2. The ERP modulations suggest that for bilinguals living in an L1 context the use of L2 enhances neural mechanisms related to inhibition. The study provides the first evidence for a direct influence of natural language use on inhibition.
School meals consumption is associated with a better diet quality of Brazilian adolescents: results from the PeNSE 2015 survey
Authors: Boklis-Berer Mirena , Rauber Fernanda , Azeredo Catarina Machado , Levy Renata Bertazzi , Louzada Maria Laura da Costa
Published: August 2021

Objective:

To assess the association between the consumption of school meals offered by the National School Feeding Program (PNAE, in the Portuguese acronym) and the diet quality of adolescents aged 11 to 19 years from Brazilian public schools.

Design:

Cross-sectional.

Setting:

Public schools in Brazil.

Participants:

A sample of 12 260 adolescents aged 11 to 19 years from 2015 National School Health Survey. High consumption of PNAE school meals were considered when the adolescents consumed school meals 5 d/week. Food consumption data were obtained from a 7-d FFQ and converted into three diet quality assessment scores, namely (1) consumption of healthy foods; (2) consumption of unhealthy foods and (3) overall diet quality. Crude and adjusted linear regression models were used to test the association between high consumption to school meals (daily consumption) and each diet quality score.

Results:

More than one-fifth of the adolescents (21·5 %) reported high consumption of school meals. High consumption of school meals was directly associated with the score of the overall diet quality (adjusted coefficient = 0·18; 95 % CI 0·07, 0·30) and healthy food consumption (adjusted coefficient = 0·42; 95 % CI 0·26, 0·57), and inversely associated with the unhealthy food consumption score (adjusted coefficient = −0·23; 95 % CI −0·35, −0·10).

Conclusion:

Our results showed that the consumption of PNAE meals may contribute to healthy eating promotion in Brazil.
Morphological Features of the Testis among Autoimmune Mouse Model and Healthy Strains
Authors: Shouman Zeinab , Marei Hany E. , Abd-Elmaksoud Ahmed , Kassab Mohamed , Namba Takashi , Masum Md. Abdul , Elewa Yaser Hosny Ali , Ichii Osamu , Kon Yasuhiro
Published: August 2021

Autoimmune diseases play a critical role in the progression of infertility in both sexes and their severity has been reported to increase with age. However, few reports have discussed their effect on the morphological features of the testis. Therefore, we compared the morphological alterations in the testes of autoimmune model mice (MRL/MpJ-Faslpr) and the control strain (MRL/MpJ) with those of their background strain (C57BL/6N) at 3 and 6 months. Furthermore, we analyzed the changes in spermatocytes, Sertoli cells, immune cells, and Zonula occludens-1 junctional protein by immunohistochemical staining. The MRL/MpJ-Faslpr mice showed a significant increase in the serum Anti-double stranded DNA antibody level, relative spleen weight, and seminiferous luminal area when compared with other studied two strains. In contrast, a significant decrease in the relative testis weight, and numbers of both Sertoli, meiotic spermatocyte was observed in MRL/MpJ-Faslpr and MRL/MpJ mice compared with C57BL/6N mice especially at 6 months. Similarly, Zonula occludens-1 junctional protein positive cells showed a significant decrease in the same strains at 6 months. However, no immune cell infiltration could be observed among the studied three strains. Our findings suggest that the increase in autoimmune severity especially with age could lead to infertility through loss of spermatogenic and Sertoli cells, rather than the disturbance of the blood–testis barrier.