bluuebunny/crossref_metadata_2025 huggingface dataset:
A General and Diastereoselective Route to Five‐Membered Carbocycles and Heterocycles from Acyclic Vinyl Sulfone‐Modified Carbohydrates
Authors: Atta Ananta Kumar , Pathak Tanmaya
Published: December 2009

Pentosyl and hexosyl acyclic vinyl sulfones having a suitably positioned leaving group reacted with externally delivered carbon, nitrogen, oxygen, and sulfur nucleophiles to afford a series of five‐membered carbocycles and heterocycles in a diastereoselective fashion. This diversity‐oriented synthetic method generates a wide range of chirally pure cyclic compounds from easily accessible starting materials and reagents.
Synthesis of a New Class of C2‐Symmetrical Biheteroaryls by Ammonium Cerium(IV) Nitrate Mediated Dimerization of 2‐(Furan‐3‐yl)pyrroles
Authors: Alcaide Benito , Almendros Pedro , Carrascosa Rocío , Torres M. Rosario
Published: December 2009

Polyfunctionalized 2‐(furan‐2‐yl)pyrroles and 2‐(furan‐3‐yl)pyrroles derived from 2‐azetidinone‐tethered allenes by two independent cerium(IV)‐mediated single‐electron oxidations provided a (4‐oxopent‐2‐enoyl)pyrrole and 3,3′‐bis(pyrrol‐2‐yl)‐2,2′‐bifurans, respectively. Access to the oxidation precursors was achieved by regiocontrolled cyclization of β‐allenamine intermediates derived from selective β‐lactam nucleus breakage of 2‐azetidinone‐tethered allenols.
Canadian Alzheimer's disease caregiver survey: baby‐boomer caregivers and burden of care
Authors: Black Sandra E. , Gauthier Serge , Dalziel William , Keren Ron , Correia Jane , Hew Huong , Binder Carin
Published: December 2009

Objective

Alzheimer's disease (AD) burdens not only the person, but also the person's caregiver(s). This burden has been linked to negative health effects for caregivers. To that end, a survey of Canadian caregivers of persons with AD/other dementias was conducted to investigate the social, physical, psychological and financial impact of AD and/or dementia‐related conditions on caregivers' quality of life.

Methods

A web‐based survey, the Canadian Alzheimer's Disease Caregiver survey, was made available through the Canadian Alzheimer's Society website and 50plus.com, an internet portal for baby boomers (BB) (people aged 50 years or older), as well as through HarrisDecima Research's e‐Vox panel. A total of 398 individuals completed the survey between 15 September and 5 November 2006.

Results

Of the 398 total respondents, 221 were identified as baby boomers who provided care to an individual with AD/dementia. Respondents identified several areas of burden of care. These included negative effects on emotional health (such as increased depression, more stress and greater fatigue), financial costs and a need to change a working situation (e.g. by retiring early, reducing work hours or refusing a promotion).

Conclusion

Caregivers of persons with AD/related dementia face important social, physical, psychological and financial pressures. These negatively affect the quality of life of caregivers with a significant increased burden being placed on live‐in caregivers versus caregivers who do not co‐reside with their care recipients. Interventions that address these pressures will not only improve the health and well‐being of caregivers, but likely also the care of persons with AD/dementia. Copyright © 2009 John Wiley & Sons, Ltd.
Syntheses and herbicidal activity of pyrazolyl benzoxazole derivatives
Authors: Xue Na , Zhou Yuhan , Wang Guowei , Miao Weirong , Qu Jingping
Published: December 2009

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In recent years, protoporphyrinogen oxidase (Protox) inhibitor herbicides are developed rapidly, because of this type of herbicides shows high herbicidal activity and low toxicity. In this paper, we prepared a series of new substituted pyrazolyl benzoxazole derivative, which were synthesized from 4‐fluorophenol, via a serial of reactions included chlorination, acylation, condensation, ring closure, methylation, nitration, and so on. All the structures are confirmed by 1H NMR, MS and element analysis. Preliminary bioassay shows that most substituted pyrazolyl benzoxazole derivatives exhibit high herbicidal activity to the tested gramineous weeds and latifoliate weeds. J. Heterocyclic Chem., (2010).
Female germline stem cell niches of earwigs are structurally simple and different from those of Drosophila melanogaster
Authors: Tworzydlo Waclaw , Kloc Malgorzata , Bilinski Szczepan M.
Published: December 2009

Stem cells function in niches, which consist of somatic cells that control the stem cells' self‐renewal, proliferation, and differentiation. Drosophila ovary germline niche consists of the terminal filament (TF) cells, cap cells, and escort stem cells; signaling from the TF cells and the cap cells is essential for maintenance of germline stem cells (GSCs). Here, we show that in the earwig Opisthocosmia silvestris, the female GSC niche is morphologically simple and consist of the TF cells and several structurally uniform escort cells. The most posterior cell of the TF (the basal cell of the TF) differs from remaining TF cells and is separated from the anterior region of the germarium by the processes of the escort cells, and consequently, does not contact the GSCs directly. We also show that between somatic cells of earwig niche argosome‐like vesicles and cytoneme‐like extensions are present. J. Morphol., 2010. © 2009 Wiley‐Liss, Inc.
Genetic polymorphism at the apolipoprotein E locus affects the outcome of chronic hepatitis B
Authors: Toniutto Pierluigi , Fattovich Giovanna , Fabris Carlo , Minisini Rosalba , Burlone Michela , Pravadelli Cecilia , Peraro Laura , Falleti Edmondo , Caldera Francesca , Bitetto Davide , Pirisi Mario
Published: December 2009

Apolipoprotein E (ApoE) and H (ApoH) genotypes are known to affect plasma lipoprotein concentrations. By modulating transport and entry of the hepatitis B virus into hepatocytes, apolipoproteins may influence the course of infection. To verify this hypothesis, 105 patients with chronic HBV infection were examined. Sixty‐two of the patients were followed‐up for a median time of 21 years. One hundred two controls were included. ApoE and ApoH genotypes were determined by the restriction fragment length polymorphism method. A trend was found for progressive overrepresentation of ApoE3/E3 among patients with advanced liver disease: 13/27 (48%) of inactive HBV carriers, 36/61 (59%) of chronic hepatitis B patients and 16/17 (94%) of patients who received liver transplants (P < 0.005). Being an E3/* carrier was associated with a lower probability of loss of HBsAg: 9/56 (16%) versus 3/6 (50%) (P < 0.05); it was also associated with a longer time before HBsAg loss (P < 0.05). No influence of ApoH genotypes on clinical outcomes was found. The probability of disease progression was higher, and that of loss of HBsAg was lower, among patients with the ApoE3 allelic variant. Downregulation and/or reduced binding of the LDL receptor may explain the more benign course of hepatitis B among carriers of ApoE2–E4. J. Med. Virol. 82:224–231, 2010. © 2009 Wiley‐Liss, Inc.
A nationwide survey of hepatitis E virus infection in the general population of Japan
Authors: Takahashi Masaharu , Tamura Kazuko , Hoshino Yu , Nagashima Shigeo , Yazaki Yasuyuki , Mizuo Hitoshi , Iwamoto Sadahiko , Okayama Masanobu , Nakamura Yoshikazu , Kajii Eiji , Okamoto Hiroaki
Published: December 2009

To investigate nationwide the prevalence of hepatitis E virus (HEV) infection in the general population of Japan, serum samples were collected from 22,027 individuals (9,686 males and 12,341 females; age, mean ± standard deviation: 56.8 ± 16.7 years; range: 20–108 years) who lived in 30 prefectures located in Hokkaido, mainland Honshu, Shikoku, and Kyushu of Japan and underwent health check‐ups during 2002–2007, and were tested for the presence of IgG, IgM, and IgA classes of antibodies to HEV (anti‐HEV) by in‐house ELISA and HEV RNA by nested RT‐PCR. Overall, 1,167 individuals (5.3%) were positive for anti‐HEV IgG, including 753 males (7.8%) and 414 females (3.4%), the difference being statistically significant (P < 0.0001). The prevalence of anti‐HEV IgG generally increased with age and was significantly higher among individuals aged ≥50 years than among those aged <50 years (6.6% vs. 2.7%, P < 0.0001). Although 13 individuals with anti‐HEV IgG also had anti‐HEV IgM and/or anti‐HEV IgA, none of them had detectable HEV RNA. The presence of HEV RNA was further tested in 50 or 49‐sample minipools of sera from the remaining 22,014 individuals, and three individuals without anti‐HEV antibodies tested positive for HEV RNA. The HEV isolates obtained from the three viremic individuals segregated into genotype 3 and were closest to Japan‐indigenous HEV strains. When stratified by geographic region, the prevalence of anti‐HEV IgG as well as the prevalence of HEV RNA or anti‐HEV IgM and/or anti‐HEV IgA was significantly higher in northern Japan than in southern Japan (6.7% vs. 3.2%, P < 0.0001; 0.11% vs. 0.01%, P = 0.0056; respectively). J. Med. Virol. 82:271–281, 2010. © 2009 Wiley‐Liss, Inc.
Alpha‐synuclein overexpression in mice alters synaptic communication in the corticostriatal pathway
Authors: Wu Nanping , Joshi Prasad R. , Cepeda Carlos , Masliah Eliezer , Levine Michael S.
Published: December 2009

α‐Synuclein (α‐Syn) is a presynaptic protein implicated in Parkinson's disease (PD). Mice overexpressing human wildtype (WT) α‐Syn under the Thy1 promoter show high levels of α‐Syn in cortical and subcortical regions, exhibit progressive sensorimotor anomalies, as well as non‐motor abnormalities and are considered models of pre‐manifest PD as there is little evidence of early loss of dopaminergic (DA) neurons. We used whole‐cell patch clamp recordings from visually identified striatal medium‐sized spiny neurons (MSSNs) in slices from α‐Syn and WT littermate control mice at 35, 90 and 300 days of age to examine corticostriatal synaptic function. MSSNs displayed significant decreases in the frequency of spontaneous excitatory postsynaptic currents (EPSCs) in α‐Syn mice at all ages. This difference persisted in the presence of tetrodotoxin, indicating it was independent of action potentials. Stimulation thresholds for evoking EPSCs were significantly higher and responses were smaller in α‐Syn mice. These data suggest a decrease in neurotransmitter release at the corticostriatal synapse. At 90 days the frequency of spontaneous GABAA receptor‐mediated synaptic currents was decreased in MSSNs but increased in cortical pyramidal neurons. These observations indicate that high levels of expression of α‐Syn alter corticostriatal synaptic function early and they provide evidence for early synaptic dysfunction in a pre‐manifest model of PD. Of importance, these changes are opposite to those found in DA‐depletion models, suggesting that before degeneration of DA neurons in the substantia nigra synaptic adaptations occur at the corticostriatal synapse that may initiate subtle preclinical manifestations. © 2009 Wiley‐Liss, Inc.
Photoresponsive nanocarriers based on PAMAM dendrimers with a o‐nitrobenzyl shell
Authors: Li Yan , Jia Xinru , Gao Min , He Hai , Kuang Guichao , Wei Yen
Published: December 2009

Gn (n = 3, 4, and 5) poly(amidoamine) (PAMAM) dendrimers were synthesized and peripherally modified with photocleavable o‐nitrobenzyl (NB) groups by reacting o‐nitrobenzaldehyde with the terminal amine groups of PAMAM dendrimers, followed by reducing the imine to amine groups with NaBH4. The NB‐modified dendrimers, Gn‐NB (n = 3, 4, and 5), were characterized by nuclear magnetic resonance and fourier transform infrared spectroscopy. The results showed that the NB groups were successfully attached on the periphery of the dendrimers with near 100% grafting efficiency. Such a photosensitive NB shell could be cut off on irradiation with 365 nm ultraviolet (UV) light. The encapsulation and release of guest molecules, that is, salicylic acid (SA) and adriamycin (ADR), by Gn‐NB were explored. The encapsulation capability of these dendrimers was found to increase as the guest molecular size was decreased and have dependence on the generation of dendrimers as well. For both of SA and ADR, the average encapsulation numbers per dendrimer decreased in the order of G4‐NB > G5‐NB > G3‐NB, indicating that the fourth generation dendrimer was a better container for the guest molecules. The rate of SA release was found to be greater with UV irradiation than that without, suggesting that the NB‐shelled PAMMAM dendrimers could function as a molecular container/box with photoresponsive characteristics. © 2009 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 48: 551–557, 2010
A green epoxidation system with poly(4‐vinylpyridine) microsphere‐supported molybdenum catalyst
Authors: Cao Lijing , Yang Mu , Wang Ge , Wei Yen , Sun Dongbai
Published: December 2009

The immobilization of molybdenum (Mo) compounds on poly(4‐vinylpyridine) (P4VP) microspheres for catalytic epoxidation was reported. P4VP‐supported Mo compounds were highly efficient and selective for the epoxidation of cis‐cyclooctene using hydrogen peroxide (H2O2) as oxygen source. When ethanol was used as solvents, outstanding catalytic activity and selectivity were observed for Mo‐containing catalysts in the epoxidation of cis‐cyclooctene. A completely green epoxidation system based on H2O2 and cleaner solvent has been achieved, and the heterogenized Mo catalyst can be recovered for five times without loss of its activity. © 2009 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 48: 558–562, 2010
Improving on analyses of self‐reported data in a large‐scale health survey by using information from an examination‐based survey
Authors: Schenker Nathaniel , Raghunathan Trivellore E. , Bondarenko Irina
Published: December 2009

Common data sources for assessing the health of a population of interest include large‐scale surveys based on interviews that often pose questions requiring a self‐report, such as, ‘Has a doctor or other health professional ever told you that you have 〈 health condition of interest〉 ?’ or ‘What is your 〈 height/weight〉 ?’ Answers to such questions might not always reflect the true prevalences of health conditions (for example, if a respondent misreports height/weight or does not have access to a doctor or other health professional). Such ‘measurement error’ in health data could affect inferences about measures of health and health disparities. Drawing on two surveys conducted by the National Center for Health Statistics, this paper describes an imputation‐based strategy for using clinical information from an examination‐based health survey to improve on analyses of self‐reported data in a larger interview‐based health survey. Models predicting clinical values from self‐reported values and covariates are fitted to data from the National Health and Nutrition Examination Survey (NHANES), which asks self‐report questions during an interview component and also obtains clinical measurements during a physical examination component. The fitted models are used to multiply impute clinical values for the National Health Interview Survey (NHIS), a larger survey that obtains data solely via interviews. Illustrations involving hypertension, diabetes, and obesity suggest that estimates of health measures based on the multiply imputed clinical values are different from those based on the NHIS self‐reported data alone and have smaller estimated standard errors than those based solely on the NHANES clinical data. The paper discusses the relationship of the methods used in the study to two‐phase/two‐stage/validation sampling and estimation, along with limitations, practical considerations, and areas for future research. Published in 2009 by John Wiley & Sons, Ltd.
Transient Grounding Characteristics of an Actual Wind Turbine Generator System at a Low‐resistivity Site
Authors: Yamamoto Kazuo , Yanagawa Shunichi , Sekioka Shozo , Yokoyama Shigeru
Published: December 2009

In order to exploit high wind conditions, wind turbine generator systems are often constructed in places where few tall structures exist; therefore, they are often struck by lightning. Much of the damage caused by lightning is from the resulting breakdown and malfunction of the electrical, communication, and control systems inside the wind turbine generator system; these breakdowns can be attributed to a rise in electric potential both within the system and in the surroundings due to lightning. Impulse tests were conducted on a wind turbine generator system at a disposal site where the conductivity of the ground was very low, like that found on the surface of the sea. The rise in ground potential of the system, and around its foundation, was measured. When a wind turbine generator system is constructed at a site where the grounding resistivity is very low, the potential rise at the wave front typically becomes larger than that of the steady state because of the inductivity of the grounding system. Therefore, it is very important that the transient characteristics of the grounding system are well understood. Copyright © 2010 Institute of Electrical Engineers of Japan. Published by John Wiley & Sons, Inc.
Zellweger syndrome with unusual findings: non‐immune hydrops fetalis, dermal erythropoiesis and hypoplastic toe nails
Authors: Dursun Ali , Gucer Safak , Ebberink M. S. , Yigit Sule , Wanders R. J. A. , Waterham H. R.
Published: December 2009

The peroxisomal biogenesis disorders (PBDs) comprise the Zellweger spectrum disorders (i.e., Zellweger syndrome, neonatal adrenoleukodystrophy, and infantile Refsum disease) and rhizomelic chondrodysplasia punctata. Peroxisomal biogenesis disorders can be caused by mutations in any of 13 currently known PEX genes, which encode peroxins involved in peroxisomal protein import and/or assembly of the organelle. We report here on a Turkish patient who presented with unusual clinical findings, that included non‐immune hydrops, dermal erythropoiesis and hypoplastic toenails, as well as common dysmorphic features of Zellweger syndrome. The patient has also pulmonary hypoplasia, which has been reported in only a few patients with Zellweger syndrome. A peroxisomal biogenesis disorder was confirmed by enzyme analysis and abnormal very long‐chain fatty acid (VLCFA) profiles in plasma and fibroblast and immunofluorescence microscopy studies. Subsequent molecular genetic analysis revealed a homozygous c.856C>T mutation (R268X) in the PEX3 gene, which made this patient the third to have a defect in this gene. In contrast to those of the two previously reported patients, the cells of this patient still contained peroxisomal membrane structures (ghosts), seen by immunofluorescence microscopy analysis. The case presented here and the two previously reported cases point out that a PEX3 gene defect may present with fairly heterogeneous clinical findings. This case also raises a possibility that hydrops fetalis may be associated with a PEX3 gene defect and that peroxisomal disorders can be considered in the etiology of hydrops fetalis as well as other cell organelle disorders when one is considering yet undiscovered complementation groups in peroxisomal disorders.
Random Variables and Probability Distributions
Authors: Cramer H.
Published: December 2009

This tract develops the purely mathematical side of the theory of probability, without reference to any applications. When originally published, it was one of the earliest works in the field built on the axiomatic foundations introduced by A. Kolmogoroff in his book Grundbegriffe der Wahrscheinlichkeitsrechnung, thus treating the subject as a branch of the theory of completely additive set functions. The author restricts himself to a consideration of probability distributions in spaces of a finite number of dimensions, and to problems connected with the Central Limit Theorem and some of its generalizations and modifications. In this edition the chapter on Liapounoff's theorem has been partly rewritten, and now includes a proof of the important inequality due to Berry and Esseen. The terminology has been modernized, and several minor changes have been made.
Who Gets What?
Authors: Stilwell Frank , Jordan Kirrily
Published: December 2009

This 2007 book addresses important contemporary concerns about social justice. It presents detailed economic evidence, but analyses it in a manner that is engaging and readily accessible to the non-specialist reader. Who Gets What? examines what has been happening to incomes and wealth in Australia, what causes increased economic inequality, and the possibility of creating a more egalitarian society. It looks at who is rich, which social groups are still in poverty, and the policies that could redistribute income and wealth more effectively.
J. S. Bach
Authors: Williams Peter
Published: December 2009

Peter Williams approaches afresh the life and music of arguably the most studied of all composers, interpreting both Bach's life by deconstructing his original obituary in the light of more recent information and his music by evaluating his priorities and irrepressible creative energy. How, even though belonging to musical families on both his parents' sides, did he come to possess so bewitching a sense of rhythm and melody and a mastery of harmony that established nothing less than a norm in Western culture? In considering that the works of a composer are his biography, the book's title A Life in Music means both a life spent making music and one revealed in the music as we know it. A distinguished scholar and performer, Williams re-examines Bach's life as an orphan and family man, as an extraordinarily gifted composer and player and as an ambitious artist who never suffered fools gladly.
The Play of Character in Plato's Dialogues
Authors: Blondell Ruby
Published: December 2009

This book attempts to bridge the gulf that still exists between 'literary' and 'philosophical' interpreters of Plato by looking at his use of characterization. Characterization is intrinsic to dramatic form and a concern with human character in an ethical sense pervades the dialogues on the discursive level. Form and content are further reciprocally related through Plato's discursive preoccupation with literary characterization. Two opening chapters examine the methodological issues involved in reading Plato 'as drama' and a set of questions surrounding Greek 'character' words (especially ethos), including ancient Greek views about the influence of dramatic character on an audience. The figure of Sokrates qua Platonic 'hero' also receives preliminary discussion. The remaining chapters offer close readings of select dialogues, chosen to show the wide range of ways in which Plato uses his characters, with special emphasis on the kaleidoscopic figure of Sokrates and on Plato's own relationship to his 'dramatic' hero.
Plato's Introduction of Forms
Authors: Dancy R. M.
Published: December 2009

Scholars of Plato are divided between those who emphasize the literature of the dialogues and those who emphasize the argument of the dialogues, and between those who see a development in the thought of the dialogues and those who do not. In this important book Russell Dancy focuses on the arguments and defends a developmental picture. He explains the Theory of Forms of the Phaedo and Symposium as an outgrowth of the quest for definitions canvassed in the Socratic dialogues, by constructing a Theory of Definition for the Socratic dialogues based on the refutations of definitions in those dialogues, and showing how that theory is mirrored in the Theory of Forms. His discussion, notable for both its clarity and its meticulous scholarship, ranges in detail over a number of Plato's early and middle dialogues, and will be of interest to readers in Plato studies and in ancient philosophy more generally.
The Grain Market in the Roman Empire
Authors: Erdkamp Paul
Published: December 2009

This book explores the economic, social and political forces that shaped the grain market in the Roman Empire. Examining studies on food supply and the grain market in pre-industrial Europe, it addresses questions of productivity, division of labour, market relations and market integration. The social and political aspects of the Roman grain market are also considered. Dr Erdkamp illustrates how entitlement to food in Roman society was dependent on relations with the emperor, his representatives and the landowning aristocracy, and local rulers controlling the towns and hinterlands. He assesses the response of the Roman authorities to weaknesses in the grain market and looks at the implications of the failure of local harvests. By examining the subject from a contemporary perspective, this book will appeal not only to historians of ancient economies, but to all concerned with the economy of grain markets, a subject which still resonates today.
Christianization and Communication in Late Antiquity
Authors: Maxwell Jaclyn L.
Published: December 2009

How did ordinary people and Church authorities communicate with each other in late antiquity and how did this interaction affect the processes of Christianization in the Roman Empire? By studying the relationship between the preacher and his congregation within the context of classical, urban traditions of public speaking, this book explains some of the reasons for the popularity of Christian sermons during the period. Its focus on John Chrysostom's sermons allows us to see how an educated church leader responded to and was influenced by a congregation of ordinary Christians. As a preacher in Antioch, Chrysostom took great care to convey his lessons to his congregation, which included a broad cross-section of society. Because of this, his sermons provide a fascinating view into the variety of beliefs held by the laity, demonstrating that many people could be actively engaged in their religion while disagreeing with their preacher.
Money and the Early Greek Mind
Authors: Seaford Richard
Published: December 2009

How were the Greeks of the sixth century BC able to invent philosophy and tragedy? In this book Richard Seaford argues that a large part of the answer can be found in another momentous development, the invention and rapid spread of coinage which produced the first ever thoroughly monetised society. By transforming social relations, monetisation contributed to the ideas of the universe as an impersonal system (presocratic philosophy) and of the individual alienated from his own kin and from the gods (in tragedy). Seaford argues that an important precondition for this monetisation was the Greek practice of animal sacrifice, as represented in Homeric Epic, which describes a premonetary world on the point of producing money. This book combines social history, economic anthropology, numismatics and the close reading of literary, inscriptional, and philosophical texts. Questioning the origins and shaping force of Greek philosophy, this is a major book with wide appeal.
Christianity in Bakhtin
Authors: Coates Ruth
Published: December 2009

The work of the great Russian theorist Mikhail Bakhtin has been examined from a wide variety of literary and theoretical perspectives. None of the many studies of Bakhtin begins to do justice, however, to the Christian dimension of his work. Christianity in Bakhtin for the first time fills this important gap. Having established the strong presence of a Christian framework in his early philosophical essays, Ruth Coates explores the way in which Christian motifs, though suppressed, continue to find expression in the work of Bakhtin's period of exile, and re-emerge in texts written during the time of his rehabilitation. Particular attention is paid to the themes of Creation, Fall, Incarnation and Christian love operating within metaphors of silence and exile, concepts which inform Bakhtin's world view as profoundly as they influence his biography.
Theory and the Novel
Authors: Williams Jeffrey
Published: December 2009

Narrative features such as frames, digressions, or authorial intrusions have traditionally been viewed as distractions from or anomalies in the narrative proper. In Theory and the Novel Jeffrey Williams exposes these elements as more than simple disruptions, analysing them as registers of narrative reflexivity, that is, moments that represent and advertise the functioning of narrative itself. Williams argues that narrative encodes and advertises its own functioning and modal form. He takes a range of novels from the English canon - Tristram Shandy, Joseph Andrews, The Turn of the Screw, Wuthering Heights, Lord Jim and Heart of Darkness are amongst the novels examined - and shows how narrative technique is never beyond or outside plot. He poses a series of theoretical questions such as about reflexitivity, imitation and fictionality, to offer a striking and original contribution to readings of the English novel, as well as to discussions of theory in general.
The Wycliffite Heresy
Authors: Ghosh Kantik
Published: December 2009

Kantik Ghosh argues that one of the main reasons for Lollardy's sensational resonance for its times, and for its immediate posterity, was its exposure of fundamental problems in late medieval academic engagement with the Bible, its authority and its polemical uses. Examining Latin and English sources, Ghosh shows how the same debates over biblical hermeneutics and associated methodologies were from the 1380s onwards conducted both within and outside the traditional university framework, and how by eliding boundaries between Latinate biblical speculation and vernacular religiosity Lollardy changed the cultural and political positioning of both. Covering a wide range of texts - scholastic and extramural, in Latin and in English, written over half a century from Wyclif to Thomas Netter - Ghosh concludes that by the first decades of the fifteenth century Lollardy had partly won the day. Whatever its fate as a religious movement, it had successfully changed the intellectual landscape of England.
Theatre, Finance and Society in Early Modern England
Authors: Leinwand Theodore B.
Published: December 2009

This interesting study examines emotional responses to socio-economic pressures in early modern England, as they are revealed in plays, historical narratives and biographical accounts of the period. These texts yield fascinating insights into the various, often unpredictable, ways in which people coped with the exigencies of credit, debt, mortgaging and capital ventures. Plays discussed include Shakespeare's The Merchant of Venice and Timon of Athens, Jonson's The Alchemist and Massinger's A New Way to Pay Old Debts. They are paired with writings by and about the finances of the corrupt Earl of Suffolk, the privateer Walter Raleigh, the royal agent Thomas Gresham, theatre entrepreneur James Burbage, and the Lord Treasurer Lionel Cranfield. Leinwand's new readings of these texts reveal a blend of affect and cognition concerning finance that includes nostalgia, anger, contempt, embarrassment, tenacity, bravado and humility.
Oral Culture and Catholicism in Early Modern England
Authors: Shell Alison
Published: December 2009

After the Reformation, England's Catholics were marginalised and excluded from using printed media for propagandist ends. Instead, they turned to oral media, such as ballads and stories, to plead their case and maintain contact with their community. Building on the growing interest in Catholic literature which has developed in early modern studies, Alison Shell examines the relationship between Catholicism and oral culture from the mid-sixteenth to the eighteenth centuries. In order to recover the textual traces of this minority culture, she expands canonical boundaries, looking at anecdotes, spells and popular verse alongside more conventionally literary material. In her archival research she uncovers many important manuscript sources. This book is an important contribution to the rediscovery of the writings and culture of the Catholic community and will be of great interest to scholars of early modern literature, history and theology.
Rousseau, Robespierre and English Romanticism
Authors: Dart Gregory
Published: December 2009

This book re-opens the question of Rousseau's influence on the French Revolution and on English Romanticism, by examining the relationship between his confessional writings and his political theory. Gregory Dart argues that by looking at the way in which Rousseau's writings were mediated by the speeches and actions of the French Jacobin statesman Maximilien Robespierre, we can gain a clearer and more concrete sense of the legacy he left to English writers. He shows how the writings of William Godwin, Mary Wollstonecraft, William Wordsworth and William Hazlitt rehearse and reflect upon the Jacobin tradition in the aftermath of the French revolutionary Terror.
The Power of the Passive Self in English Literature, 1640–1770
Authors: Gordon Scott Paul
Published: December 2009

Challenging recent work that contends that seventeenth-century English discourses privilege the notion of a self-enclosed, self-sufficient individual, The Power of the Passive Self in English Literature recovers a counter-tradition that imagines selves as more passively prompted than actively choosing. This tradition - which Scott Paul Gordon locates in seventeenth-century religious discourse, in early eighteenth-century moral philosophy, in mid eighteenth-century acting theory, and in the emergent novel - resists autonomy and defers agency from the individual to an external 'prompter'. Gordon argues that the trope of passivity aims to guarantee a disinterested self in a culture that was increasingly convinced that every deliberate action involves calculating one's own interest. Gordon traces the origins of such ideas from their roots in the non-conformist religious tradition to their flowering in one of the central texts of eighteenth-century literature, Samuel Richardson's Clarissa.
The Rhetoric of Sensibility in Eighteenth-Century Culture
Authors: Goring Paul
Published: December 2009

The Rhetoric of Sensibility in Eighteenth-Century Culture explores the burgeoning eighteenth-century fascination with the human body as an eloquent, expressive object. This wide-ranging study examines the role of the body within a number of cultural arenas - particularly oratory, the theatre and the novel - and charts the efforts of projectors and reformers who sought to exploit the textual potential of the body for the public assertion of modern politeness. Paul Goring shows how diverse writers and performers including David Garrick, James Fordyce, Samuel Richardson, Sarah Fielding and Laurence Sterne were involved in the construction of new ideals of physical eloquence - bourgeois, sentimental ideals which stood in contrast to more patrician, classical bodily modes. Through innovative readings of fiction and contemporary manuals on acting and public speaking, Goring reveals the ways in which the human body was treated as an instrument for the display of sensibility and polite values.
British Romanticism and the Science of the Mind
Authors: Richardson Alan
Published: December 2009

In this provocative and original study, Alan Richardson examines an entire range of intellectual, cultural, and ideological points of contact between British Romantic literary writing and the pioneering brain science of the time. Richardson breaks new ground in two fields, revealing a significant and undervalued facet of British Romanticism while demonstrating the 'Romantic' character of early neuroscience. Crucial notions like the active mind, organicism, the unconscious, the fragmented subject, instinct and intuition, arising simultaneously within the literature and psychology of the era, take on unsuspected valences that transform conventional accounts of Romantic cultural history. Neglected issues like the corporeality of mind, the role of non-linguistic communication, and the peculiarly Romantic understanding of cultural universals are reopened in discussions that bring new light to bear on long-standing critical puzzles, from Coleridge's suppression of 'Kubla Khan', to Wordsworth's perplexing theory of poetic language, to Austen's interest in head injury.
Fiction, Famine, and the Rise of Economics in Victorian Britain and Ireland
Authors: Bigelow Gordon
Published: December 2009

We think of economic theory as a scientific speciality accessible only to experts, but Victorian writers commented on economic subjects with great interest. Gordon Bigelow focuses on novelists Charles Dickens and Elizabeth Gaskell and compares their work with commentaries on the Irish famine (1845–1852). Bigelow argues that at this moment of crisis the rise of economics depended substantially on concepts developed in literature. These works all criticized the systematized approach to economic life that the prevailing political economy proposed. Gradually the romantic views of human subjectivity, described in the novels, provided the foundation for a new theory of capitalism based on the desires of the individual consumer. Bigelow's argument stands out by showing how the discussion of capitalism in these works had significant influence not just on public opinion, but on the rise of economic theory itself.
Modernism and the Celtic Revival
Authors: Castle Gregory
Published: December 2009

In Modernism and the Celtic Revival, Gregory Castle examines the impact of anthropology on the work of Irish Revivalists such as W. B. Yeats, John M. Synge and James Joyce. Castle argues that anthropology enabled Irish Revivalists to confront and combat British imperialism, even as these Irish writers remained ambivalently dependent on the cultural and political discourses they sought to undermine. Castle shows how Irish Modernists employed textual and rhetorical strategies first developed in anthropology to translate, reassemble and edit oral and folk-cultural material. In doing so, he claims, they confronted and undermined inherited notions of identity which Ireland, often a site of ethnographic curiosity throughout the nineteenth-century, had been subject to. Drawing on a wide range of post-colonial theory, this book should be of interest to scholars in Irish studies, post-colonial studies and Modernism.
Modernism, Male Friendship, and the First World War
Authors: Cole Sarah
Published: December 2009

Sarah Cole examines the rich literary and cultural history of masculine intimacy in the twentieth century. Cole approaches this complex and neglected topic from many perspectives - as a reflection of the exceptional social power wielded by the institutions that housed and structured male bonds; as a matter of closeted and thwarted homoerotics; as part of the story of the First World War. Cole shows that the terrain of masculine fellowship provides an important context for understanding key literary features of the modernist period. She foregrounds such crucial themes as the over-determined relations between imperial wanderers in Conrad's tales, the broken friendships that permeate Forster's fictions, Lawrence's desperate urge to make culture out of blood brotherhood and the intense bereavement of the war poet. Cole argues that these dramas of compelling and often tortured male friendship have helped to define a particular spirit and voice within the literary canon.
Literature and Legal Discourse
Authors: Polloczek Dieter Paul
Published: December 2009

The intersection between law and literature is a developing area in literary studies. Existing work has argued that literature provides an imaginary forum in which legal ideals and practices may be tested. In Literature and Legal Discourse: Equity and Ethics from Sterne to Conrad Dieter Polloczek develops this idea by comparing the notion of equity, or ethics, in fiction with its legal equivalent. He shows how the novel, with its increasing social scope and formal sophistication, provided a means of transmitting, questioning and refining society's traditions, values and modes of self-questioning. Polloczek analyses the links between actual legal fictions like substituted judgements, notions of equity, literary tropes and the construction and representation of social bonds through sentiment, philanthropy and marginalisation. Pollozcek's study is both theoretical and historical, covering a period that extends from the eighteenth century to the modernist period, and texts from Sterne, Dickens, Bentham and Conrad.
Dante and the Making of a Modern Author
Authors: Ascoli Albert Russell
Published: December 2009

Leading scholar Albert Russell Ascoli traces the metamorphosis of Dante Alighieri – minor Florentine aristocrat, political activist and exile, amateur philosopher and theologian, and daring experimental poet – into Dante, author of the Divine Comedy and perhaps the most self-consciously 'authoritative' cultural figure in the Western canon. The text offers a comprehensive introduction to Dante's evolving, transformative relationship to medieval ideas of authorship and authority from the early Vita Nuova through the unfinished treatises, The Banquet and On Vernacular Eloquence, to the works of his maturity, Monarchy and the Divine Comedy. Ascoli reveals how Dante anticipates modern notions of personalized, creative authorship and the phenomenon of 'Renaissance self-fashioning'. Unusually, the book examines Dante's career as a whole offering an important point of access not only to the Dantean oeuvre, but also to the history and theory of authorship in the larger Italian and European tradition.
The Syntax-Morphology Interface
Authors: Baerman Matthew , Brown Dunstan , Corbett Greville G.
Published: December 2009

Syncretism - where a single form serves two or more morphosyntactic functions - is a persistent problem at the syntax-morphology interface. It results from a 'mismatch' whereby the syntax of a language makes a particular distinction but the morphology does not. This pioneering book provides a full-length study of inflectional syncretism, presenting a typology of its occurrence across a wide range of languages. The implications of syncretism for the syntax-morphology interface have long been recognised: it argues either for an enriched model of feature structure (thereby preserving a direct link between function and form), or for the independence of morphological structure from syntactic structure. This book presents a compelling argument for the autonomy of morphology and the resulting analysis is illustrated in a series of formal case studies within Network Morphology. It will be welcomed by all linguists interested in the relation between words and the larger units of which they are a part.
Relevance and Linguistic Meaning
Authors: Blakemore Diane
Published: December 2009

The importance of discourse markers (words like 'so', 'however', and 'well') lies in the theoretical questions they raise about the nature of discourse and the relationship between linguistic meaning and context. They are regarded as being central to semantics because they raise problems for standard theories of meaning, and to pragmatics because they seem to play a role in the way discourse is understood. In this new and important study, Diane Blakemore argues that attempts to analyse these expressions within standard semantic frameworks raise even more problems, while their analysis as expressions that link segments of discourse has led to an unproductive and confusing exercise in classification. She concludes that the exercise in classification that has dominated discourse marker research should be replaced by the investigation of the way in which linguistic expressions contribute to the inferential processes involved in utterance understanding.
The Acquisition of Complex Sentences
Authors: Diessel Holger
Published: December 2009

This book presents a comprehensive study of how children acquire complex sentences. Drawing on observational data from English-speaking children aged 2 to 5, Holger Diessel investigates the acquisition of infinitival and participial complement clauses, finite complement clauses, finite and nonfinite relative clauses, adverbial clauses, and coordinate clauses. His investigation shows that the development of complex sentences originates from simple non-embedded sentences and that two different developmental pathways can be distinguished: complex sentences including complement and relative clauses evolve from simple sentences that are gradually expanded to multiple-clause constructions, and complex sentences including adverbial and coordinate clauses develop from simple sentences that are integrated in a specific biclausal unit. He argues that the acquisition process is determined by a variety of factors: the frequency of the various complex sentences in the ambient language, the semantic and syntactic complexity of the emerging constructions, the communicative functions of complex sentences, and the social-cognitive development of the child.
Fluent Aphasia
Authors: Edwards Susan
Published: December 2009

Fluent aphasia is a language disorder that follows brain damage, causing difficulty in finding the correct words and structuring sentences. Speakers also experience problems in understanding language, severely impairing their ability to communicate. In this informative study Susan Edwards provides a detailed description of fluent aphasia, by drawing widely on research data, and by comparing fluent aphasia with other types of aphasia as well as with normal language. She discusses evidence that the condition affects access to underlying grammatical rules as well as to the lexicon, and explores the relationship between language and the brain, the controversy over aphasia syndromes, the assessment of aphasia via standardized tests, and the analysis of continuous speech data. Extensive examples of aphasic speech are given, and the progress of one fluent aphasic speaker is discussed in detail. Written by an internationally renowned expert, this book will be invaluable to linguists and practitioners alike.
Pragmatic Impairment
Authors: Perkins Michael
Published: December 2009

Pragmatics - the way we communicate using more than just language - is particularly problematic for people with speech disorders. Through an extensive analysis of how pragmatics can go wrong, this 2007 book not only provides a clinically useful account of pragmatic impairment, but it also throws light on how pragmatics functions in healthy individuals. Michael Perkins brings mainstream and clinical pragmatics together by showing that not only can our understanding of pragmatics be aided by the study of pragmatic impairment, but that clinical and theoretical pragmatics are better served by treating pragmatic ability and disability within a single framework. It is a comprehensive book aimed primarily at linguists and psycholinguists rather than clinicians, and includes illustrative material on conditions such as autism and aphasia and a wide range of other communication disorders in both children and adults.
New Zealand English
Authors: Gordon Elizabeth , Campbell Lyle , Hay Jennifer , Maclagan Margaret , Sudbury Andrea , Trudgill Peter
Published: December 2009

New Zealand English - at just 150 years old - is one of the newest varieties of English, and is unique in that its full history and development are documented in extensive audio-recordings. The rich corpus of spoken language provided by New Zealand's 'mobile disk unit' has provided insight into how the earliest New Zealand-born settlers spoke, and consequently, how this new variety of English developed. On the basis of these recordings, this book examines and analyses the extensive linguistic changes New Zealand English has undergone since it was first spoken in the 1850s. The authors, all experts in phonetics and sociolinguistics, use the data to test previous explanations for new dialect formation, and to challenge current claims about the nature of language change. The first ever corpus-based study of the evolution of New Zealand English, this book will be welcomed by all those interested in phonetics, sociolinguistics, historical linguistics and dialectology.