bluuebunny/crossref_metadata_2025 huggingface dataset:
Intervention Effect of Aerobic Exercise on Physical Fitness, Emotional State and Mental Health of Drug Addicts: A Systematic Review and Meta-Analysis
Authors: Ye Xing , Liu Renyi
Published: January 2023

This study aims to discuss evidence for the efficacy of aerobic exercise in reducing drug addiction and improving the physical and mental health of drug addicts. We systematically searched several online databases as of the end of September 2022, including PubMed, EMBASE, the Cochrane Library, Web of Science, Scopus, Science Direct, CNKI, VIP, CBM, and Wanfang. All articles were identified, screened and included according to the inclusion or exclusion criteria. The Cochrane Handbook for Systematic Reviews of Interventions was used as a criterion for assessing the methodological quality of included studies. Random and fixed effects models were used for the analysis of standard mean differences (SMD) or mean differences (MD) with their 95% confidence intervals (CI). A total of 27 studies involving 2022 drug addicts were finally included in the analysis. The results of the meta-analysis showed that aerobic exercise could improve the physical fitness [body fat percentage: MD = −0.74, 95%CI (−1.40, −0.08), vital capacity: MD = 213.79, 95%CI (46.28, 381.29), muscle force: MD = 1.21, 95%CI (0.34, 2.08), flexibility: MD = 4.61, 95%CI (2.98, 6.25), balance: MD = 9.95, 95%CI (6.29, 13.62)], regulate the systolic blood pressure: MD = −4.38, 95%CI (−7.08, −1.68), diastolic blood pressure: MD = −2.66, 95% CI (−3.82, −1.51), beats per minute: MD =−1.92, 95%CI (−3.19, −0.65); emotional state [anxiety: MD = −4.56, 95% CI (−5.67, −3.45), depression: MD = −3.28, 95%CI (−5.16, −1.39), drug craving: SMD= −1.68,95% CI(−2.56, −0.80)], and promote the mental health [anxiety: MD = −0.22, 95%CI (−0.33, −0.11), obsessive−compulsive: MD = −0.26, 95%CI (−0.50, −0.03), somatization: MD = −0.21, 95%CI (−0.27, −0.14), depression: MD = −0.21, 95%CI (−0.28, −0.15), psychoticcism: MD = −0.12, 95%CI (−0.18, −0.06), phobic anxiety: MD = −0.11, 95%CI (−0.16, −0.07), paranoid ideation: MD = −0.09, 95%CI (−0.15, −0.02), interpersonal sensitivity: MD = −0.16, 95%CI (−0.22, −0.10), hostility: MD = −0.12, 95%CI (−0.18, −0.05)], with statistically significant differences(p < 0.05)] of drug addicts. Thus, aerobic exercise could effectively improve the physical fitness, emotional state and mental health of drug addicts, and reduce their drug addiction. For clinical practitioners and researchers, this study could provide more reliable evidence for addiction treatment.
Participation in Population Health Interventions by Older Adults in Poland: Barriers and Enablers
Authors: Cianciara Dorota , Lewtak Katarzyna , Poznańska Anna , Piotrowicz Maria , Gajewska Małgorzata , Urban Ewa , Sugay Larysa , Rutyna Anna
Published: January 2023

Background: The participation of older adults in population health interventions constitutes a key factor in their physical, mental and social health. The aim of this study was to determine variables considered as enablers and barriers to participation in health programmes. Methods: The conceptual framework of the study was developed and population health interventions were operationalised as health programmes. A total of 805 older adults participated in a questionnaire survey. The questionnaire included questions about socio-demographic, health and social connectedness-related factors as well as participation in population health interventions/programmes. Multiple logistic regression was used to examine the relationship between respondents’ characteristics and participation in the intervention. Results: Participation in health programmes was declared by 316 respondents. The enablers of participation were general practitioner’s affability (OR = 2.638 [1.453–4.791], p = 0.001), three or more social activities (OR = 3.415 [1.477–7.894], p = 0.004), taking part in support groups (OR = 4.743 [1.255–17.929], p = 0.022) and involvement in Universities of the Third Age (OR = 2.829 [1.093–7.327], p = 0.032). The barriers were primary education (OR = 0.385 [0.215–0.690], p = 0.001), infrequent general practitioner’s appointments (OR = 0.500 [0.281–0.888], p = 0.018) and lack of social activity (OR = 0.455 [0.299–0.632], p < 0.001). Conclusion: The enablers of participation appeared to solely include variables regarding health service utilisation, patient experience and social activity, i.e., interpersonal and community relationships, not intrapersonal factors.
Association between Malnutrition and Depression in Patients with Cancer: The Importance of Nutritional Status Evaluation in Cancer Care
Authors: Nucci Daniele , Gianfredi Vincenza , Ferrara Pietro , Santangelo Omar Enzo , Varotto Beatrice , Feltrin Alessandra , Galiano Antonella , Nardi Mariateresa
Published: January 2023

Cancer patients are at risk of several comorbid conditions, including nutritional issues and mental health illnesses. The objective of the current study was to estimate the prevalence, upon hospital admission, of depression and malnutrition among adults with cancer. A retrospective chart review was conducted using health information collected as part of routine assistance. Nutritional status was measured through structured tools, including body mass index (BMI), Nutrition Risk Screening (NRS) 2002, and dietary intake needs. Depression was assessed with the Hospital Anxiety and Depression Scale (HAD). Cancer site, disease stage, length of hospitalization, age, and sex were also considered. Multivariate analyses were used to investigate the association between malnutrition and depression. In summary, our study reveals that malnutrition increases the risk of depression among cancer patients. The findings can also be used in clinical oncology for the implementation of appropriate prevention and treatment interventions in order to reduce the extent of depression and thus improve cancer patients’ quality of life and survival rate.
Sexual Orientation Microaggression Experiences and Coping Responses of Lesbian, Gay, and Bisexual Individuals in Taiwan: A Qualitative Study
Authors: Huang Yu-Te , Chou Wen-Jiun , Hang Yi-Chen , Yen Cheng-Fang
Published: January 2023

This qualitative study explored the sexual orientation microaggression (SOM) experiences and coping strategies of lesbian, gay, and bisexual (LGB) individuals in Taiwan. In total, 30 LGB individuals (17 women and 13 men; 17 homosexual and 13 bisexual individuals) who experienced SOMs participated in qualitative, semistructured interviews, during which their SOM experiences were assessed. Through the interviews, several types of SOMs were identified, corresponding to three main types of microaggression (microassaults, microinsults, and microinvalidations) previously identified in Western studies. The participants reported various coping responses to SOMs, ranging from active responses to choosing not to respond, to protecting themselves or to minimizing the negative consequences of confrontation. The results provide mental health professionals with insight regarding the contexts of and coping responses to the SOMs experienced by LGB individuals.
Are There Differences between the Stress Responses of Philippine Men and Women to the COVID-19 Pandemic?
Authors: Periyakoil Divya , Periyakoil Preethi , Tee Cherica A. , Spanos Costas J. , Diener-West Marie , Tee Michael , Prata Ndola
Published: January 2023

The SARS-CoV-2 pandemic has had a deleterious impact on human health since its beginning in 2019. The purpose of this study was to examine the psychosocial impact of the COVID-19 pandemic in the Philippines and determine if there were differential impacts on women compared to men. A web-based survey was conducted in the Luzon Islands of the Philippines, during the pandemic quarantine. A total of 1879 participants completed online surveys between 28 March–12 April 2020. A bivariate analysis of both men and women for each psychological measure (stress, anxiety, depression, and impact of COVID-19) was conducted. Multivariable logistic regression models were built for each measure, dichotomized as high or low, separately for men and women. Younger age (p < 0.001), being married (p < 0.001), and being a parent (p < 0.004) were associated with women’s poor mental health. Marriage and large household size are protective factors for men (p < 0.002 and p < 0.0012, respectively), but marriage may be a risk factor for women (p < 0.001). Overall, women were disproportionately negatively impacted by the pandemic compared to men.
Detecting Medication Risks among People in Need of Care: Performance of Six Instruments
Authors: Dreischulte Tobias , Sanftenberg Linda , Hennigs Philipp , Zöllinger Isabel , Schwaiger Rita , Floto Caroline , Sebastiao Maria , Kühlein Thomas , Hindenburg Dagmar , Gagyor Ildikó , Wildgruber Domenika , Hausen Anita , Janke Christian , Hölscher Michael , Teupser Daniel , Gensichen Jochen ,   on behalf of the BACOM Study Group
Published: January 2023

Introduction: Numerous tools exist to detect potentially inappropriate medication (PIM) and potential prescribing omissions (PPO) in older people, but it remains unclear which tools may be most relevant in which setting. Objectives: This cross sectional study compares six validated tools in terms of PIM and PPO detection. Methods: We examined the PIM/PPO prevalence for all tools combined and the sensitivity of each tool. The pairwise agreement between tools was determined using Cohen’s Kappa. Results: We included 226 patients in need of care (median (IQR age 84 (80–89)). The overall PIM prevalence was 91.6 (95% CI, 87.2–94.9)% and the overall PPO prevalence was 63.7 (57.1–69.9%)%. The detected PIM prevalence ranged from 76.5%, for FORTA-C/D, to 6.6% for anticholinergic drugs (German-ACB). The PPO prevalences for START (63.7%) and FORTA-A (62.8%) were similar. The pairwise agreement between tools was poor to moderate. The sensitivity of PIM detection was highest for FORTA-C/D (55.1%), and increased to 79.2% when distinct items from STOPP were added. Conclusion: Using a single screening tool may not have sufficient sensitivity to detect PIMs and PPOs. Further research is required to optimize the composition of PIM and PPO tools in different settings.
Impact of Driver’s Age and Gender, Built Environment, and Road Conditions on Crash Severity: A Logit Modeling Approach
Authors: Lee Dongkwan , Guldmann Jean-Michel , von Rabenau Burkhard
Published: January 2023

The purpose of this research is (1) to investigate the relationship between crash severity and the age and gender of the at-fault driver, the socio-economic characteristics of the surrounding environment, and road conditions, and (2) to explain the probability of a bodily injury crash, including fatality, with the alternative being a property damage only crash. In contrast to earlier research that has focused on young and old drivers, age is considered here on its lifetime continuum. A logit model is adopted and the gender and age of the at-fault drivers are part of the independent explanatory variables. The unit of analysis is the individual crash. Since age is a continuous variable, this analysis shows more precisely how age impacts accident severity and identifies when age has little effect. According to the results, the type of vehicle, timing of the crash, type of road and intersection, road condition, regional and locational factors, and socio-economic characteristic have a significant impact on crashes. Regarding the effect of age, when an accident occurs the probability of bodily injury or fatality is 0.703 for female drivers, and 0.718 for male drivers at 15 years of age. These probabilities decline very slightly to 0.696 and 0.711, respectively, around 33 years of age, then very slightly increase to 0.697 and 0.712, respectively, around 47.5 years of age. The results show that age affects crash severity following a polynomial curve. While the overall pattern is one of a downward trend with age, this trend is weak until the senior years. The policy implications of the results are discussed.
Effect of Energy Utilization and Economic Growth on the Ecological Environment in the Yellow River Basin
Authors: Lu Chenyu , Liu Wei , Huang Ping , Wang Yueju , Tang Xianglong
Published: January 2023

In the 21st century, problems relating to energy, economy, and the environment have become increasingly severe across the world, and critical issues around environmental pollution, ecological imbalance, and an energy crisis have emerged. The Yellow River basin is an important ecological barrier, economic region, and energy base in Northern China. Environmental pollution in the Yellow River basin has become increasingly problematic, especially since the reform and opening up of China, along with the rapid development of the industrial economy and mining for energy resources. In this study, 64 of the 73 prefecture-level cities in the Yellow River basin were selected as the research object, including 18 cities in the downstream region, 26 cities in the midstream region, and 20 cities in the upstream region. The data used in this study were from 2004 to 2019. On the basis of temporal variation and spatial differentiation of the three factors of economy, energy, and environment, the impulse response function and the generalized method of moments (GMM) were adopted to evaluate the effects of energy utilization and economic growth on the ecological environment. Their roles in affecting the ecological environment were analyzed along with the underlying mechanisms. Overall, energy utilization, economic growth, and ecological environment are in good condition, showing a steady upward trend. Regional differences still exist, but the gap is gradually narrowing. There are some differences in the impulse response of the ecological environment to the economic growth and energy utilization in the upstream, midstream, and downstream regions of the Yellow River basin. The effect is leveled out or weakened in the middle and later phases of the impact. Compared with the downstream and upstream regions, economic growth and energy utilization in the midstream regions have less impact on the ecological environment. The two factors of energy utilization potential and economic potential have significant positive impacts on the ecological environment. The current situation of energy utilization has to some extent a positive impact on the ecological environment. Economic scale has a certain negative impact on the ecological environment.
A Review of Filtration Performance of Protective Masks
Authors: Wang Ao-Bing , Zhang Xin , Gao Li-Jun , Zhang Tao , Xu Hui-Juan , Bi Yan-Jun
Published: January 2023

Masks are essential and effective small protective devices used to protect the general public against infections such as COVID-19. However, available systematic reviews and summaries on the filtration performance of masks are lacking. Therefore, in order to investigate the filtration performance of masks, filtration mechanisms, mask characteristics, and the relationships between influencing factors and protective performance were first analyzed through mask evaluations. The summary of filtration mechanisms and mask characteristics provides readers with a clear and easy-to-understand theoretical cognition. Then, a detailed analysis of influencing factors and the relationships between the influencing factors and filtration performance is presented in. The influence of the aerosol size and type on filtration performance is nonlinear and nonconstant, and filtration efficiency decreases with an increase in the gas flow rate; moreover, fitness plays a decisive role in the protective effects of masks. It is recommended that the public should wear surgical masks to prevent COVID-19 infection in low-risk and non-densely populated areas. Future research should focus on fitness tests, and the formulation of standards should also be accelerated. This paper provides a systematic review that will be helpful for the design of masks and public health in the future.
Effects of Temperature and Tempo: Evaluating How Much Time in a Typical Community-Based Yoga Class Is Moderate-Intensity Aerobic Activity
Authors: Dysart Anna , Harden Samantha
Published: January 2023

The 2nd edition of the Physical Activity Guidelines for Americans (PAG) recommends, in part, 150 min of moderate-intensity aerobic physical activity. The PAG states that yoga may be able to help meet the guidelines for moderate-intensity aerobic exercise for adults and older adults. Our study aims to objectively measure the proportion of time participants’ activity that is categorized as moderate-intensity aerobic activity based on heart rate data and to subjectively measure rate of perceived exertion (RPE). Participants completed the Stanford Leisure-Time Activity Categorical item to establish baseline PAG aerobic activity compliance. Participants then completed four separate 1-h yoga sessions at different tempos (cadence) and temperatures while wearing heart rate monitors. During and directly after the session they also marked their RPE on a modified 10-point scale. All participants reached moderate-intensity aerobic activity for at least some portion of a yoga session based on heart rate monitor data and RPE. The average duration of moderate intensity was 32.75% of the class across all four class types, with no significant differences by condition. Age was a significant factor in time spent in moderate-to-vigorous physical activity for only the thermo-neutral Hatha classes (p = 0.010). Tempo, temperature, and baseline activity levels were not significant factors in time spent in moderate-to-vigorous intensity physical activity based on Pearson Correlation and the Kruskal–Wallis test. Hatha and Vinyasa yoga classes, at room or hot temperatures, can be used to meet a portion of the PAG moderate-intensity activity recommendations.
Promoting Physical Activity and Health in the Workplace: A Qualitative Study among University Workers, Spain
Authors: Casimiro-Andújar Antonio Jesús , Checa Juan Carlos , Lirola María-Jesús , Artés-Rodríguez Eva
Published: January 2023

The social changes we have been experiencing in recent years are generating anxiety that, together with sedentary lifestyles and poor health habits, are leading to premature ageing of society, in addition to the high rates of obesity and associated morbidity. In order to improve the lifestyles of the university community, the objective of this research project was the implementation of the UAL Activa programme based on physical activity. The beneficiaries were UAL staff from different sections, a total of 68 participants aged between 28 and 61 years (Mage = 49.36). Additionally, a total of 12 final year students of the degree in physical activity and sport sciences were responsible for designing and developing the exercise tasks. In-depth interviews were held with the participants of this project about the different benefits that their participation had brought them. The results obtained from the analysis with Nvivo v.10. showed five thematic blocks on the perceived improvements in physical fitness, physical condition, mood and emotional state, assessment of the new lifestyle, and social relations. In conclusion, the benefits of physical activity and the need to continue implementing action and intervention plans to encourage and promote its practice in all sectors of the population were highlighted.
How Does the Experience of Forest Recreation Spaces in Different Seasons Affect the Physical and Mental Recovery of Users?
Authors: Chen Rui , Gao Yu , Zhang Ruixin , Zhang Zhi , Zhang Weikang , Meng Huan , Zhang Tong
Published: January 2023

Background: In recent years, increasing attention has been given to the recovery effect of the forest environment on physical and mental health. Therefore, providing users with a high-quality forest landscape space is a very important research topic for forest landscape designers and forest resource managers. Main purpose: From the perspective of different seasons, this study explores the differences in landscape perceptions and physical and mental recovery of users when they experience different forest recreation spaces and the interactions between them. Methods: First, this study used virtual reality video experience and questionnaires for participants. Then, the paired-samples t test, one-way ANOVA and the independent-samples t test were used for statistical analysis. Finally, we also used structural equation models to analyze the relationship between landscape perception and recovery. Main results: (1) The restoration effect and perception of forest recreation spaces on people are influenced by space types and seasonal factors. (2) People’s restoration from forest environments is a gradual process from spatial cognition to emotional response. (3) The perception of the natural attributes and form of the recreation space plays a key role in the restorative effect of the environment to people, while the natural form is more important in spring than autumn. Based on the above conclusions, we suggest that the characteristic factors of the landscape environment and their different restoration effects for users in different dimensions should be considered when planning forest recreation space.
Understanding Social Exercise: Desire and Intention to Participate in Running Crews
Authors: Won Doyeon , Kim Hyung-hoon , Bae Jung-sup
Published: January 2023

The current study investigated the determinants of the desire and intention to participate in an inner-city ‘running crew’ among social runners using a theoretical framework of the model of goal-directed behavior (MGB). Data were obtained from 245 social runners in Korea using an online questionnaire and primarily analyzed with the structural equation modeling technique. The results indicated that the desire to participate in a running crew was influenced most by positive anticipated emotions, followed (in descending order) by attitudes, negative anticipated emotions, social norms, perceived behavioral control, and the frequency of past behaviors. Runners’ behavioral intentions were predicted by desire but not directly related to perceived behavioral control and the frequency of past behavior. Overall, the study emphasized the importance of positive anticipated emotions and behavioral desire, among others, to encourage recreational runners’ participation in social running activities. Given that social runners rely on mobile apps to participate in running crew activities, the current study’s results have practical implications for running crew organizers, sports-branded app developers, and health promotion agencies.
Reciprocal Associations between Depressive Symptoms, Life Satisfaction, and Eudaimonic Well-Being in Older Adults over a 16-Year Period
Authors: Joshanloo Mohsen , Blasco-Belled Ana
Published: January 2023

The dual-continua model of mental health distinguishes between mental illness (presence of mental disorders, such as depression) and mental well-being (presence of positive traits and abilities). This model also distinguishes between hedonic well-being (e.g., affect balance and life satisfaction) and eudaimonic well-being (i.e., optimal psychological and social functioning, as indicated for example by having a purpose in life). We examined the relationships between depressive symptoms (a common indicator of mental illness), life satisfaction, and eudaimonic well-being. The study used a sample of 17,056 participants from England whose data were collected at eight intervals of approximately two years over a 16-year period, from 2004 to 2019. The mean age of the sample in the first wave was 58.843 years, with a standard deviation of 12.617 years (women = 55.2%). We disentangled within- and between-person sources of variance to examine whether increases or decreases in one variable preceded changes in the other variables at the next time point. We found positive reciprocal relationships between life satisfaction and eudaimonic well-being and negative reciprocal relationships between the two well-being dimensions and depressive symptoms. These results suggest that within-person increases in well-being are followed by future decreases in depressive symptoms, and within-person increases in depressive symptoms are followed by future decreases in well-being. Therefore, low levels of mental well-being in older adults may be considered a risk factor for depression, and well-being interventions (such as those focused on meaning-making) may serve as a protective factor against depression in older adults.
Tumour Genetic Heterogeneity in Relation to Oral Squamous Cell Carcinoma and Anti-Cancer Treatment
Authors: Feller Gal , Khammissa Razia Abdool Gafaar , Ballyram Raoul , Beetge Mia-Michaela , Lemmer Johan , Feller Liviu
Published: January 2023

Oral squamous cell carcinoma (SCC) represents more than 90% of all oral cancers and is the most frequent SCC of the head and neck region. It may affect any oral mucosal subsite but most frequently the tongue, followed by the floor of the mouth. The use of tobacco and betel nut, either smoked or chewed, and abuse of alcohol are the main risk factors for oral SCC. Oral SCC is characterized by considerable genetic heterogeneity and diversity, which together have a significant impact on the biological behaviour, clinical course, and response to treatment and on the generally poor prognosis of this carcinoma. Characterization of spatial and temporal tumour-specific molecular profiles and of person-specific resource availability and environmental and biological selective pressures could assist in personalizing anti-cancer treatment for individual patients, with the aim of improving treatment outcomes. In this narrative review, we discuss some of the events in cancer evolution and the functional significance of driver-mutations in carcinoma-related genes in general and elaborate on mechanisms mediating resistance to anti-cancer treatment.
Consumer Visual and Affective Bias for Soothing Dolls
Authors: Chu Yu-Hsiu , Chou Li-Wei , Lin He-Hui , Chang Kang-Ming
Published: January 2023

Soothing dolls are becoming increasingly popular in a society with a lot of physical and mental stress. Many products are also combined with soothing dolls to stimulate consumers’ desire for impulse buying. However, there is no research on the relationship between consumers’ purchasing behavior, consumers’ preference for soothing dolls, and visual preference. The purpose of this study was to examine the possible factors that affect the emotional and visual preferences of soothing dolls. Two local stores’ sales lists were used to extract three different types of dolls. The 2D and 3D versions of these three dolls were used. Subjective emotional preferences were examined by the self-assessment manikin (SAM) scale, with 5-point Likert scales for valence and arousal factors. An eye tracker was used to examine visual preferences, both before and after positive/negative emotion stimulation by the International Affective Picture System (IAPS). There were 37 subjects involved, with an age range of 20–28 years. The experimental results show that the average valence/arousal scores for 2D/3D dolls were (3.80, 3.74) and (2.65, 2.68), respectively. There was no statistical difference, but both 2D and 3D pictures had high valence scores. Eye tracker analysis revealed no gaze difference in visual preference between 2D and 3D dolls. After negative emotional picture stimulation, the observation time of the left-side doll decreased from 2.307 (std 0.905) to 1.947 (std 1.038) seconds, p < 0.001; and that of the right-side picture increased from 1.898 (std 0.907) to 2.252 (std 1.046) seconds, p < 0.001. The average observation time ratio of the eye on the 3D doll was 40.6%, higher than that on the 2D doll (34.3%, p = 0.02). Soothing dolls may be beneficial for emotion relaxation. Soothing dolls always have high valence features according to the SAM evaluation’s measurement. Moreover, this study proposes a novel research model using an eye-tracker and the SAM for the SOR framework.
Adherence to Mediterranean Diet and Risk of Pancreatic Cancer: Systematic Review and Meta-Analysis
Authors: Nucci Daniele , Nardi Mariateresa , Cinnirella Andrea , Campagnoli Emanuela , Maffeo Manuel , Perrone Pier Mario , Shishmintseva Viktoriia , Grosso Francesca Maria , Castrofino Ambra , Castaldi Silvana , Romanò Luisa , Gianfredi Vincenza
Published: January 2023

Pancreatic cancer (PC) represents the 6th cause of cancer death. Although the aetiology of PC is not completely understood, numerous risk factors have been identified in association with this cancer, among them diet. However, little is known about the association between the Mediterranean Diet (MedDiet) and the risk of PC. For this reason, we conducted a systematic review with meta-analysis according to the PRISMA guidelines, searching on three databases (PubMed/MEDLINE, Scopus, and EMBASE). The protocol was registered in PROSPERO. Both fixed and random effect models were performed. The Effect size was reported as a hazard ratio (HR) with a 95% Confidence Interval (CI). A total of eight articles were included. The methodological quality of the included meta-analyses was high. Our results show that a higher adherence to the MedDiet is associated with a lower risk of PC [HR:0.82 (0.76–0.88) p < 0.001, based on 1,301,320 subjects]. The results were also confirmed in sensitivity and subgroups analyses (avoidance of potential overlapping effects, type of tools used to assess dietary intake and the diagnosis of PC, prevalence and incidence of PC risk, country where the studies took place, sex, and cancer site). Promoting a higher adherence to the MedDiet could be an effective approach to reduce the risk of PC.
Sleep Quality and Cognitive Function after Stroke: The Mediating Roles of Depression and Anxiety Symptoms
Authors: Niu Shuzhen , Liu Xianliang , Wu Qian , Ma Jiajia , Wu Songqi , Zeng Li , Shi Yan
Published: January 2023

This study examined the association between post-stroke cognitive function and sleep status at 30 days post-stroke and evaluated the role of anxiety and depression as potential mediators of that association. The participants in this study were 530 acute ischemic stroke (IS) patients. Sleep disturbance at 30 days post-stroke was assessed by the Pittsburgh Sleep Quality Index. Basic patient information, cognitive function, depression, and anxiety status were assessed before discharge from the hospital. Stratified linear regression analysis models were fit to examine the associations between post-stroke sleep quality and the influencing factors. A structural equation model was developed to evaluate the role of anxiety and depression as potential mediators of sleep quality and cognitive function. At 30 days post-stroke, 58.7% of IS patients had sleep disturbance. Women and older IS patients were more likely to suffer poorer sleep quality (p < 0.05). A stratified linear regression analysis showed that the inclusion of cognitive function variables and indicators of depression and anxiety were statistically significant in predicting improvement in the sleep disturbance of AIS patients. Cognitive function, depression, anxiety, and sleep status were selected to construct a structural equation model. The total effect of cognitive function on sleep status was −0.274, with a direct effect of −0.097 and an indirect effect (through depression) of −0.177. The total effect of anxiety on sleep status was 0.235, with a direct effect of 0.186 and an indirect effect (through depression) of 0.049. IS patients often experience poor sleep quality. Depression in IS patients mediates two pathways: the pathway through which cognitive function affects sleep quality and the pathway through which anxiety affects sleep quality.
Optimising Access to Healthcare for Patients Experiencing Homelessness in Hospital Emergency Departments
Authors: Currie Jane , Stafford Amanda , Hutton Jennie , Wood Lisa
Published: January 2023

The ED is often the first and sometimes the only place where people experiencing homelessness seek medical assistance. While access to primary healthcare is a preferable and more cost-effective alternative to ED, for many reasons, people experiencing homelessness are much less likely to have a regular General Practitioner compared to those living in stable accommodation. Drawing on a growing body of emergency care and homelessness literature and practice, we have synthesised four potential interventions to optimise access to care when people experiencing homelessness present to an ED. Although EDs are in no way responsible for resolving the complex health and social issues of their local homeless population, they are a common contact point and therefore present an opportunity to improve access to healthcare.
No Causal Effects Detected in COVID-19 and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Two Sample Mendelian Randomization Study
Authors: Xu Wangzi , Cao Yu , Wu Lin
Published: January 2023

New clinical observational studies suggest that Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a sequela of COVID-19 infection, but whether there is an exact causal relationship between COVID-19 and ME/CFS remains to be verified. To investigate whether infection with COVID-19 actually causes ME/CFS, this paper obtained pooled data from the Genome Wide Association Study (GWAS) and analyzed the relationship between COVID susceptibility, hospitalization and severity of COVID and ME/CFS, respectively, using two-sample Mendelian randomization (TSMR). TSMR analysis was performed by inverse variance weighting (IVW), weighted median method, MR-Egger regression and weighted mode and simple mode methods, respectively, and then the causal relationship between COVID-19 and ME/CFS was further evaluated by odds ratio (OR). Eventually, we found that COVID-19 severity, hospitalization and susceptibility were all not significantly correlated with ME/CFS (OR:1.000,1.000,1.000; 95% CI:0.999–1.000, 0.999–1.001, 0.998–1.002; p = 0.333, 0.862, 0.998, respectively). We found the results to be reliable after sensitivity analysis. These results suggested that SARS-CoV-2 infection may not significantly contribute to the elevated risk of developing CFS, and therefore ME/CFS may not be a sequela of COVID-19, but may simply present with symptoms similar to those of CFS after COVID-19 infection, and thus should be judged and differentiated by physicians when diagnosing and treating the disease in clinical practice.
Do Youth Dream of Gender Stereotypes? The Relationship among Gender Stereotyping, Support for Feminism, and Acceptance of Gender-Based Violence
Authors: Leon Carmen M. , Aizpurua Eva
Published: January 2023

Although gender roles have continued to evolve, stereotypical perceptions about men and women persist. From a traditional perspective, men are viewed as aggressive, competitive, and dominant, whereas women are expected to be pretty, affectionate, and passive. The relevance of gender stereotypes lies in the way such expectations reinforce gender inequality and discrimination. Gender stereotyping is also linked to an increased acceptance of gender-based violence, as such conceptions are based on the premise that women are subordinate to men. The current study uses data from the Barometer on Youth and Gender, conducted by the Centro Reina Sofía in 2021 (N = 1201), to analyze the potential associations among gender stereotyping, support for feminism, and acceptance of gender-based violence among young people in Spain (15–29 years old). The results show that young people ascribe, to some extent, stereotypical characteristics to women and men and point to the existence of gender-based occupational stereotypes. Our results shed light on the role that gender stereotyping plays in support for feminism and the acceptance of gender-based violence. They also provide valuable information about the magnitude of gender-stereotypical perceptions among young men and women.
Predictive Models of Life Satisfaction in Older People: A Machine Learning Approach
Authors: Shen Xiaofang , Yin Fei , Jiao Can
Published: January 2023

Studies of life satisfaction in older adults have been conducted extensively through empirical research, questionnaires, and theoretical analysis, with the majority of these studies basing their analyses on simple linear relationships between variables. However, most real-life relationships are complex and cannot be approximated with simple correlations. Here, we first investigate predictors correlated with life satisfaction in older adults. Then, machine learning is used to generate several predictive models based on a large sample of older adults (age ≥ 50 years; n = 34,630) from the RAND Health and Retirement Study. Results show that subjective social status, positive emotions, and negative emotions are the most critical predictors of life satisfaction. The Support Vector Regression (SVR) model exhibited the highest prediction accuracy for life satisfaction in older individuals among several models, including Multiple Linear Regression (MLR), Ridge Regression (RR), Least Absolute Shrinkage and Selection Operator Regression (LASSO), K Nearest Neighbors (KNN), and Decision Tree Regression (DT) models. Although the KNN and DT models exhibited better model fitting than MLR, RR, and LASSO, their performances were poor in terms of model validation and model generalization. These results indicate that machine learning is superior to simple correlations for understanding life satisfaction among older adults.
Does Long-Term Care Literacy Matter in Evaluating Older Care Recipients’ Satisfaction with Care Managers? Empirical Evidence from Japanese Survey Data
Authors: Wang Ziyan , Fukayama Kaori , Niu Bing
Published: January 2023

In this study, we focused on the long-term care literacy of care recipients (older adults currently receiving formal care services) and examined its relationship with satisfaction with their care managers by using a unique individual dataset of Japanese people aged 65 years and older. To address the problem of non-respondent bias, we applied inverse probability weighting and the Heckman probit model for estimation. We found that the probability of older adults evaluating their satisfaction regarding the six aspects of care manager measurement increased with an increasing level of care literacy. However, concerning the level of satisfaction with their care managers, we only observed significant increases in the aspects of “Explanation power” and “Attitude and manners” as the level of care literacy increased. Covariates, such as age, gender, family structure, level of certification for long-term care, reasons for choosing the care manager, utilization of long-term care services, and the manner in which older respondents answered the survey questions, also mattered regarding the evaluation process of satisfaction of older adults. In Japan, utilizing formal care services based on the long-term care insurance system is complicated and sometimes difficult for older adults to understand. In this survey, 35% of older care recipients had inadequate care literacy. Improving the care literacy of older adults is important for better use of formal care services and increased satisfaction.
Pilot Trial of Workable: A Therapist-Supported Digital Program for Injured Workers
Authors: Crawford Joanna , Spence Jay , Lovegrove Tali , Tam Edman , Collins Daniel , Harvey Samuel B. , Deady Mark
Published: January 2023

Workplace sickness absence is a major public health and economic problem, and common mental disorders (CMDs) such as anxiety and depression are associated with particularly high rates of long-term sickness absence. Effective return-to-work (RTW) interventions are required. This pilot study investigates the feasibility, acceptability, and potential effectiveness of a new therapist-assisted Web-based RTW intervention (Workable) for injured workers on sick leave for a psychological or physical injury. A single-group open pilot trial design was used, with assessments at pre-treatment and post-treatment. The intervention consisted of 6 weeks of online modules and 6 coaching calls from a psychologist. A total of 13 participants were recruited and 9 completed all questionnaires. Program adherence was high, with 92% of participants completing the 6-week intervention. Participants reported high levels of intervention satisfaction and ease of use. There were large and significant reductions between pre- and post-treatment on measures of depression, anxiety, stress, and workdays missed over the past four weeks, along with a significant increase in self-reported work ability. These results suggest that Workable is a feasible and acceptable intervention for injured workers, with the potential to improve mental health and RTW outcomes. A randomized controlled trial is required to determine the efficacy of the intervention.
Correlates of Physical Activity in Brazilian Older Adults: The National Health Survey 2019
Authors: da Silva Amanda Santos , Melo João Carlos do Nascimento , Pereira Zainovan Serrão , dos Santos Jullyane Caldas , Silva Roberto Jerônimo dos Santos , Araújo Raphael Henrique de Oliveira , Sampaio Ricardo Aurélio Carvalho
Published: January 2023

Engagement in physical activity (PA) depends on intrapersonal, interpersonal/cultural, organizational, physical environment and political factors. Considering that it is important to understand this phenomenon in different populational contexts, this study aimed to investigate the factors related to engagement in PA according to sociodemographic aspects, eating habits, self-rated health, activities of daily living, noncommunicable diseases, mental health and public policies in Brazilian older people. This study had a cross-sectional design and used data from the Brazilian National Health Survey, 2019. Sample size was composed of 22,726 participants, aged 60 years or older, of both sexes, and all the data were collected by interview/questionnaire. According to the adjusted logistic regression, males were more active than females (OR = 1.59 (95% CI 1.40–1.80)), and those living in northern and northeastern Brazil were more likely to be inactive when compared to the southeastern region. Moreover, those with a higher educational level and income (OR = 1.36 (1.06–1.73) and OR = 1.60 (1.22–2.11)); with healthy eating habits (OR = 1.05 (1.03–1.06)); with positive self-rated health (OR = 2.67 (95% CI 1.51–4.71)); with better functional autonomy (OR = 1.22 (1.17–1.27)); and who reported that there was some public place (square, park, closed street, beach) to go for a walk, exercise or practice sport close to their home were more likely to be active (OR = 1.49 (1.34–1.67)). Sociodemographic factors, healthy eating habits, positive self-rated health, higher functioning in activities of daily living and living close to places where PA is practiced were associated with regular engagement in PA (i.e., ≥150 min/week).
The Peer Effect in Promoting Physical Activity among Adolescents: Evidence from the China Education Panel Survey
Authors: Zhou Zhengqing , Li Xinchen , Zhang Zhanjia
Published: January 2023

For a long time, studies on the peer effect of physical activity among adolescents have focused on relevance rather than causality. This article provides empirical evidence of the peer effect of physical activity among adolescents using data from the China Education Panel Survey. The results show that the peer effect increases physical activity by about 6.757–8.984 min per week among classmates, a finding consistent with previous studies. Using the instrumental variable approach and considering the potential missing variables, the peer effect increases physical activity by 23.923–27.410 min per week, representing a threefold increase. In addition, the general attitude towards sports in class plays a significantly influential role, accounting for 20% of the peer effect of physical activity.
The Security and Driving Factors of the Innovative Ecosystem: Evidence from the Yellow River Basin
Authors: Wu Yanxia , Yang Shuaishuai , Liu Fangnan , Cao Yuxuan , Jiang Mingyue
Published: January 2023

Ecological protection and high-quality development of the Yellow River Basin have always been seriously restricted by its unreasonable economic structure and low level of innovation. A two-dimensional indicator system was constructed to evaluate the security of the innovative ecosystem in the Yellow River Basin and identify its driving factors. The R clustering, the method of coefficient of variation, and the entropy method were used to screen and empower the indicators, and then the Lotka–Volterra symbiotic coupling model was introduced innovatively to calculate the security index and analyze its spatio-temporal evolution. Finally, the fixed-effect regression model and Granger causality test were used to identify the driving factors. It was found that (1) The security of the innovative ecosystem in the Yellow River Basin from 2012 to 2021 showed an overall upward tendency, but it was still at a low level, and the innovative landscape community lagged behind the innovative biome for a long time; (2) The security status of the innovative ecosystem showed a differential pattern of “high in the east and south, and lower in the west and north”; (3) Innovation transformation ability, innovation consumption capacity, education, and natural ecological environment are crucial driving factors for improving the security level of an innovative ecosystem.
Quality of Life in Amazonian Women during Cervical Cancer Treatment: The Moderating Role of Spirituality
Authors: Moysés Rosana , Marques Inês , Santos B. Daiana , Benzaken Adele , Pereira M. Graça
Published: January 2023

This study aimed to examine the contribution of psychological variables to quality of life (QoL) of Amazonian women and to analyze the moderating role of spirituality in the relationship between psychological morbidity and Qol and between illness perception and QoL. This cross-sectional study included 119 women undergoing treatment for cervical cancer (CC). The Pearson correlation test was used to evaluate the relationship between sociodemographic, clinical, and psychological variables. To test how psychological morbidity, illness perception, and spirituality contribute to QoL, a path analysis was performed and to test the moreating role of spirituality, a moderation analysis was conducted. The results revealed that the presence of symptoms, high psychological morbidity, negative body image, and threatening illness perception were predictors of lower QoL. Spirituality moderated the relationship between psychological morbidity and QoL, and between illness perception and QoL. The moderating role of spirituality emphasizes its role as a coping strategy and should be included in cancer treatment. Interventions should target psychological morbidity, threatening illness perception, and address women’s concerns with body image and sexual concerns. CC treatment should include interprofessional healthcare teams addressing the biological and psychosocial factors of Amazonian women. As a result of this study a mobile application to monitor women’s health, adapted to cultural and social characteristics, was created.