bluuebunny/crossref_metadata_2025 huggingface dataset:
Are elevated systemic bile acids involved in the pathophysiology of sarcopenia and liver injury following gastric bypass?
Authors: Bourseau S , Bozadjieva-Kramer N , Goffaux A , Baldin P , Etogo-Asse F , Trefois P , Lanthier N
Published: July 2023

Bariatric surgery is currently the most effective treatment for sustained weight loss in severe obesity. However, recent data describe the development of liver damage and in particular massive steatosis and cholangitis in some patients, for which certain pathophysiological mechanisms are suggested such as bacterial overgrowth, malabsorption or sarcopenia. We describe the case of a patient presenting with a new liver dysfunction 6 years after a gastric bypass. The work-up revealed sarcopenic obesity characterised by low muscle mass and low muscle function as well as elevated fasting bile acids, severe liver steatosis and cholangitis. The pathophysiology of this disease is complex and multifactorial but could include bile acid toxicity. Bile acids are increased in cases of liver steatosis, but also in cases of gastric bypass and malnutrition. In our opinion, they may contribute to the loss of muscle mass and the vicious circle observed in this situation. Treatment with enteral feeding, intravenous albumin supplementation and diuretics reversed the liver dysfunction and the patient was discharged from hospital
Diverticulitis associated pancreatitis: a report of 2 cases and review of the literature
Authors: Colin H , Ndjekembo Shango D , Pilet B , Waignein F , Yengue P
Published: July 2023

Duodenal diverticula are the second most common type of digestive diverticula after those in the colon. They are present in approximately 27% of patients who undergo upper digestive endoscopy. Most of these diverticula, especially those located near the papilla, are asymptomatic. However, in rare cases, they can be associated with obstructive jaundice (Lemmel Syndrome), bacterial infection, pancreatitis, or bleeding. In this report, we present two cases of acute obstructive pancreatitis caused by duodenal diverticulitis. Both patients were managed conservatively, resulting in a positive outcome.
Electron holes in a regularized kappa background
Authors: Haas Fernando , Fichtner Horst , Scherer Klaus
Published: July 2023

Abstract. The pseudopotential method is used to derive electron hole structures in a suprathermal plasma with a regularized κ probability
distribution function background. The regularized character allows the exploration of small κ values beyond the standard suprathermal case for which κ>3/2 is a necessary condition. We found the nonlinear dispersion relation yielding the amplitude of the electrostatic
potential in terms of the remaining parameters, in particular the drift velocity, the wavenumber and the spectral index. Periodic, solitary wave,
drifting and non-drifting solutions have been identified. In the linear limit, the dispersion relation yields generalized Langmuir and electron
acoustic plasma modes. Standard electron hole structures are regained in the κ≫1 limit.
NYADRAN: BENTUK AKULTURASI AGAMA DENGAN BUDAYA JAWA
Authors: Rosydiana Wildan Novia
Published: July 2023

Abstract

Nyadra is a symbol of the relationship between ancestors, nature and each other. This is a ritual pattern that contains local culture and Islamic values. So do not be surprised if the implementation of Nyadran is still related to Buddhist culture and Hindu-Animism which was then assimilated into Islamic values ​​by Wali Songo. In addition, this study will investigate the relationship between Nyadranan and religious values. A qualitative research approach is applied to answer the research questions. These results show a very strong relationship. There are 3 religious values ​​with the nyadran tradition, namely the value of worship aimed at worshiping Allah, the two values ​​of muamalah aiming so that the Islamic community and others do not discriminate against each other, the three values ​​of silaturrahmi aim to make brothers unbroken and more harmonious and peaceful.

Keywords: Religion, Local Culture, Nyadran Tradition

 

Abstrak

Nyadran  merupakan simbol hubungan antara leluhur, alam dan sesama. Ini adalah pola ritual yang mengandung budaya lokal dan nilai-nilai Islam. Maka tidak heran jika pelaksanaan Nyadran masih berkaitan dengan budaya Buddha dan Hindu-Animisme yang kemudian diasimilasi ke nilai-nilai Islam oleh Wali Songo. Selain itu, penelitian ini akan menyelidiki bagaimana hubungan antara Nyadranan dan nilai-nilai agama. Pendekatan penelitian kualitatif diterapkan untuk menjawab pertanyaan penelitian. Hasil ini menunjukkan hubungan yang sangat kuat. Nilai agama dengan tradisi nyadran ada 3 yaitu nilai ibadah bertujuan untuk beribadah kepada Allah, kedua nilai muamalah bertujuan agar masyarakat islam dan yang lain tidak saling membedakan, ketiga nilai silaturrahmi bertujuan agar antar saudara tidak terputus dan lebih rukun serta damai.

Kata Kunci: Agama, Budaya lokal, Tradisi Nyadran
MHD VISCOELASTIC STAGNATION-POINT FLOW AROUND A STRETCHING SHEET WITH INDUCED MAGNETIC FIELD AND VISCOUS DISSIPATION
Authors: Patgiri Indushri , Das Utpal Jyoti
Published: July 2023

The present study deals with a steady MHD stagnation-point flow of incompressible viscoelastic fluid in a porous medium around a stretching/shrinking sheet. The influence of induced magnetic field, heat source parameter and viscous dissipation are considered. The resulting nonlinear partial differential equations are solved under suitable boundary conditions using the bvp4c method. The effect of various physical parameters affecting on the flow has been studied. It is observed that the viscoelastic parameter enhances the induced magnetic field profile and temperature profile, whereas fluid velocity reduces. Moreover, the stretch parameter has a significant influence on the fluid velocity. The temperature profile can be improved by increasing the viscoelastic parameter, magnetic parameter, heat source parameter and radiation parameter, while the opposite effect is observed for Eckert number, reciprocal of the magnetic Prandtl number and Prandtl number.
Simple Extractive Spectrophotometric Method for Determination of Molnupiravir from Pharmaceutical Formulation
Authors: Rajan V. Rele , Prathamesh P Tiwatane
Published: July 2023

Simple sensitive and accurate spectrophotometric methods have developed for the estimation of molnupiravir in pharmaceutical dosage form. The methods are based on the formation of coloured complexes by the drug with reagents like bromophenol blue, solochrome dark blue and bromocresol green in acidic medium. The ion associated complexes were formed and quantitatively extracted under the experimental condition in chloroform. The absorbance values were measured at 420nm, 495nm and 430nm respectively. The proposed methods were validated statistically. Recoveries of methods were carried out by standard addition methods. The linearity was found to be 1.0-12.0μg/ml, 2 -14μg/ml, 1-10μg/ml for methods 1, 2 and 3 respectively. The low values of standard deviation and percentage RSD indicate high precision of methods. Hence these methods are useful for routine estimation of molnupiravir in tablets.
Design, Fabrication, and Analysis of Resveratrol and Piperine-Loaded Chitosan Nanoparticles with the Purpose of Providing an Enhanced Parkinson's Disease Treatment
Authors: Nirale Komal , Wadaskar Pallavi , Rajgure Mukul
Published: July 2023

Nanoformulation plays an essential function in emphasising the efficiency of reaching medications such as chemotherapeutic treatments and phytochemicals, and this significance is becoming increasingly recognised. In the course of this experiment, we focused on increasing the bioavailability of resveratrol lby loading it into nanoparticles. Doing so has the potential to reduce the toxicity that is a side effect of conventional formulation as well as minimise the amount of times a dose needs to be administered. The polymer, in its capacity as a carrier, plays a vital role in transporting the drug over the blood-brain barrier, which may be effective in bringing about the desired therapeutic effect. Piperine, acting as both a bio enhancer and an MAO inhibitor, has the potential to not only boost the effectiveness of resveratrol but also provide an additional mode of action that can be used to treat Parkinson's disease in a manner that is both efficient and effective. Additionally, piperine has the potential to be used in place of MAO-B inhibitors like selegline and rosagline. This provides a boost to the ongoing work on particle size in relation to two different medications and a polymer.
從國際經驗評估是否調降或取消金融業營業稅【月旦時論】
Authors: 潘俊男 潘俊男
Published: July 2023

本文希望透過借鏡其他國家的經驗，評估是否調降或取消我國金融業營業稅，並進一步了解這些調整對於金融業競爭力、稅負公平性以及整體經濟發展的影響。期望在維護金融業良好經營環境與確保公平、可持續之稅制之間達到平衡。
EVALUATION OF PHYTOCHEMICAL AND ANTIOXIDANT PROPERTIES OF VARIOUS HALOPHYTES COLLECTED FROM PICHAVARAM REGION
Authors: A. PUSHPARANI  , S.VALLI  , S. SHAMINI
Published: July 2023

Mangrove halophytes are highly influential in economical utilities such as food, fuel and Medicinals. Antioxidant and Phytochemical activities were highly significant in these samples. The synthesis of metabolites such as phenols, flavonoids and other bioactive molecules were observed and analysed. In the current script the phytochemical screening and antioxidant assays such as DPPH and ABTS were carried out for aqueous, methanol and hexane extracts of mangrove halophytes such as Ipomoea I. pescaprae, Sesuvium portulacastrum and Suaeda maritima. The preliminary phytochemical screening indicates the presence of different phytoconstituents present in the free samples. For antioxidant activity DPPH radical scavenging assay and ABTS radical scavenging assay were performed.
The impact of the Covid-19 pandemic on self-efficacy in Assistant Psychologists in the UK
Authors: Dunning Georgia , Teager Alistair , Methley Abigail , Knott Katie , Ong Leanna
Published: July 2023

Background/Aims/Objectives

A novel coronavirus (Covid-19) was discovered in December 2019 (WHO, 2020). This meant changes in working for psychological staff, such as increased remote working, wearing of personal protective equipment (PPE), and taking on different tasks out of their job remit (Coetzer & Bichard, 2020). The potential for Assistant Psychologists (APs) to work in unfamiliar areas raised concerns regarding their self-efficacy. The present study investigated general levels of self-efficacy within APs during Covid-19, and whether it affected specific job roles (BPS, 2020a).

Methodology/Methods

A novel survey with 15 items relating to self-efficacy was completed online by 124 Assistant Psychologists via a self-selected sample.

Results/Finding

There were 87 participants (70 per cent) who remained in their usual role and 37 (30 per cent) deployed into other roles with a psychological focus. Overall, self-efficacy reduced across groups, as well as an individual tasks such as completing psychological assessments, delivering prescribed short-term interventions, and facilitating groups (p = <.005). Neither group reported significant changes in their self-efficacy for engaging in research, audit, or service evaluation, or creating training resources (p = >.05). APs who were deployed had a significant reduction in self-efficacy for facilitating reflective spaces (p = .005) but those who continued in their usual role did not (p = .341).

Discussion/Conclusion

Self-efficacy for direct clinical work (e.g. interventions) was negatively affected by Covid-19 in APs, whereas indirect clinical work (e.g. research/audit/service evaluation) was not. This suggests that supervisors of APs should be aware that self-efficacy is likely to decrease concerning future waves of Covid-19, regardless of being deployed or not.
Outcomes of robotic sacrocolpopexy
Authors: Oh Sumin , Shin Jung-Ho
Published: July 2023

This review aimed to summarize the complications and surgical outcomes of robot-assisted sacrocolpopexy. Nineteen original articles on 1,440 robotic sacrocolpopexies were reviewed, and three systematic reviews and meta-analyses were summarized in terms of intraoperative, perioperative, postoperative, and/or surgical outcomes. Robotic sacrocolpopexy has demonstrated low overall complication rates and favorable surgical outcomes. Nevertheless, long-term follow-up outcomes regarding objective and/or subjective prolapse recurrence, reoperation rates, and mesh-related complications remain unclear. Further research is required to demonstrate whether the robotic approach for sacrocolpopexy is feasible or can become the modality of choice in the future when performing sacrocolpopexy.
Verification of the integration process of algorithms and sensor data for
mental health applications
Authors: Lopez Victoria , Llamocca Pavel , Urgelés Diego , Jiménez Yury , Guevara Cesar , Viñals Carlos , Espinosa Maria
Published: July 2023

Mood disorders are becoming more frequent and, especially after the
pandemic years, the importance of analysing and preventing such disorders
has become clear. In the worst cases, people can suffer from depression or
bipolar disorder leading to hospitalization or sick leave with serious
economic and social consequences for the individual and their environment.
Thanks to the development of technology, there are increasingly useful
portable devices for monitoring individual daily activity. The data
collected is very useful for understanding not only the individual's
environment but also for characterizing their emotional profile. However,
good monitoring requires the use of a diverse set of information sources.
Medical consultations are the traditional source of information but in many
cases this information is lacking or insufficient. The new sources of
information are diverse: smart devices such as smart watches or even the
mobile phone itself, portable sensors of various types and even activity
records on social networks. All these data can be integrated and processed
in such a way that a characterization profile of behaviour related to the
emotional state of the individual is determined. However, the manufacturers
of these devices apply aggregation algorithms to the monitored data to
provide the client with a friendlier and easier to interpret version, but
they do not usually provide the raw data collected by the sensors
(accelerometer, gyroscope, temperature, etc.). There is still no regulated
standardization that obliges the manufacturer to provide the data to the
owners of the devices. Both raw data and aggregation algorithms work like a
black box in most cases. The information presented by the device
applications (generally apps) is very relevant and the interpretation of the
users has direct consequences on their behaviour (behaviour modification,
medication administration, etc.). For this reason, it is essential to verify
the algorithms used in the previous process, guaranteeing that the
information integrated (and presented) really corresponds to the information
collected by the sensors. In this paper we present a suitable system for the
verification of aggregated data from personal activity monitoring sensors.
The system includes a parsing algorithm that makes the data structure and
relates it to the output. The effectiveness of the algorithm has been tested
with real data over a period of two years and for both daytime activity and
sleep quality monitoring. The algorithm is perfectly scalable to be used on
any device, so the computer system presented can be useful for future
computer auditing of this type of process.
Formulasi Dan Evaluasi Balsam Aroma Terapi Menggunakan Minyak Lemon (Oleum Citri. L) Dengan Cera Alba Sebagai Stabilizing Agent
Authors: Salsabila Laura Salwa , Shafira Intan , Azhar Moniqa Aulia , Ryanti Gading Ayu Sekar , Aurelia Riri , Sitorus Maria Apriyani Helina
Published: July 2023

Balsam merupakan salah satu bentuk sediaan setengah padat yang digunakan sebagai obat luar. Balsam tersebut memiliki indikasi untuk meredakan nyeri pada sendi dengan memberikan sensasi hangat, balsam digunakan sebagai aromaterapi, pada sediaan balsam kali ini, digunakan cera alba sebagai zat penstabil (stabilizing agent). Penelitian ini bertujuan untuk membuat sediaan balsam sesuai dengan formula, menentukan konsistensi sediaan balsam, meliputi uji pH, organoleptis, homogenitas, daya lekat dan daya sebar sediaan balsam. Hasil evaluasi menunjukkan bahwa balsam dengan menggunakan basis cera alba sebesar 15% memiliki pH yang cocok untuk kulit, daya sebar yang sesuai, daya lekat yang baik, dan organoleptis yang memenuhi syarat SNI. Sediaan balsam aromaterapi memiliki homogenitas yang baik, serta tidak mengalami perubahan warna dan bau setelah 14 hari. Berdasarkan penelitian yang telah dilakukan, dapat disimpulkan bahwa minyak lemon (oleum citri) dapat diformulasikan menjadi sediaan balsam aromaterapi yang stabil dan memenuhi syarat serta dapat bertahan selama 14 hari dengan konsentrasi cera alba sebesar 15%.
HISTORICAL PRECONDITIONS FOR THE CREATION OF FIELD COLLECTIONS IN THE FORENSIC UNITS OF THE RUSSIAN INTERIOR MINISTRY
Authors: Рыжков И.В.
Published: July 2023

Одно из центральных мест в информационном обеспечении выявления, раскрытия и расследования преступлений занимают натурные коллекции, являющиеся элементом экспертно-криминалистических учетов и справочно-информационных фондов (справочно-вспомогательных учетов). Современное состояние и положение фондов объектов, представленных в натурной форме, в системе криминалистической регистрации МВД России детерминировано первоначальными целями их ведения, развитием методов и средств судебно-экспертных исследований, непрерывным совершенствованием представления о сущности и структуре массивов криминалистически значимой информации, а также содержанием действовавших ранее нормативных правовых актов и методических рекомендаций к ним. В статье проведен анализ деятельности отечественных ЭКП во второй половине XX века по формированию и ведению натурных коллекций, результатом которого является установление конкретных предпосылок, обусловивших современное состояние криминалистических натурных коллекций.

One of the central places in the information support for the detection, disclo-sure and investigation of crimes is occupied by full-scale collections, which are an element of forensic records and reference and information funds (reference and auxiliary records). The current state and position of the funds of objects presented in full-scale form in the system of forensic registration of the Ministry of Internal Affairs of Russia is determined by the initial goals of their management, the de-velopment of methods and means of forensic research, continuous improve-ment of the idea of the essence and structure of arrays of criminally significant information, as well as previously valid regulatory legal acts and methodologi-cal recommendations to them. In this connection, the article analyzes the activities of domestic ECPs in the second half of the XX century on the formation and maintenance of full-scale collections, the result of which is the establishment of specific prerequi-sites that led to the modern idea of forensic full-scale collections.
Pengembangan Media Pembelajaran Kosakata Bahasa Arab dengan Permainan My Happy Route di Sekolah Dasar
Authors: Ahmad Alaudin , Muhlis Nur Khozim , Fathih Muhammad Amin
Published: July 2023

Vocabulary learning that is called mufradat in Arabic demands teacher creativity in presenting innovations that accommodate increased learning outcomes. However, the fact is that mufradat learning in Raudhatul Qur'an Elementary School is not on target, so researchers see the need for learning innovations using the Happy Route which aims to accommodate the ability to memorize vocabulary. The aims of this research are to develop media through the game of my happy route at the Raudhatul Qur'an school and measure its effectiveness. This study uses the Research and Development (R&D) Borg and Gall model. The procedure uses 8 stages, namely: Potential and problems, data collection, product design, design validation, design revision, product testing, product revision, usage test. The results of this study indicate that the development of the Happy Route game is carried out by product design, content development, feasibility testing, field trials and product finalization. The results of the feasibility test showed that the products created and designed by the researchers were suitable for use as learning media due to an increase in the score from the pretest, which averaged 80 to the post-test, to an average of 94.4. Through this product, children become enthusiastic about learning and memorizing vocabulary according to their material.
Pengembangan Sumber Daya Manusia Melalui Pelatihan Dasar Robotika Menggunakan Mikrokontroller
Authors: Rasyid Anuar , Muhammad Firdaus , Mukti Bambang Tri , Hasra Muhammad Rayhan , Rahmawati Riska , Rahmawati Riska , Melinda Lisa , Jessica Ditya , Fitri Azizatul , Wulandari Soffi , Monica Nasa
Published: July 2023

Kuliah Kerja Nyata merupakan program pengabdian masyarakat yang dilaksanakan di perguruan tinggi sebagai bentuk implementasi Tri Dharma Perguruan Tinggi. Kegiatan Kuliah Kerja Nyata yang dilakukan oleh tim pengabdian untuk Desa Muara Basung ini yaitu Pelatihan Dasar Robotika Menggunakan Mikrokontroler Arduino.Program unggulan ini ditujukan kepada siswa SMK yang konsentrasi jurusannya berhubungan dengan pemanfaatan mikrokontroler atau lain semacamnya. Kegiatan pengabdian ini diawali dengan pengenalan modul yang akan di praktekkan dilanjutkan dengan menerangkan cara menghubungkan modul ke mikrokontroler serta pemahaman pemahaman bahasa assembly. Kegiatan ini bertujuan agar meningkatkan minat siswa dan juga membuka wawasan terhadap perkembangan teknologi yang semakin maju serta diharapkan agar bisa diterapkan di lingkungan Desa Muara Basung.
Pelatihan Penyusunan Laporan Keuangan bagi Guru SMK Akuntansi di Jakarta Barat: Pendekatan e-learning
Authors: Mayangsari Sekar , Mahendrajaya Raditya , Brillianto Ahmad Solahuddin
Published: July 2023

Financial Reporting based on IT with Digital-based learning management workshop is the existence of new knowledge that can be applied by teachers during the learning process with their students, especially making questions or quizzes using Google Classroom and Google Forms. The subjects of this workshop are the teachers of the Senior High School – Majoring Accounting (SMK). A digital-based learning workshop for 5 days, namely accounting cycle and financial reporting preparation using ACCURATE including Certification Online learning workshops that have been organized by the Master of Accounting provide new understanding and skills to SMK-Accounting teachers in using ACCURATE as an one accounting software for prepare financial report. The drawback of this activity is the limited facilities and infrastructure available owned by teachers to support digital- based learning, as there are still few teachers who have laptops or computers to support learning and internet signal instability. Contribution of this activity is to support schools to encourage the ability of educators to carry out certification as a skill proved as financial report preparer.
Hubungan Pengetahuan Kesehatan Reproduksi, dan Sumber informasi terhadap Sikap Remaja dalam Upaya Pencegahan Kehamilan Remaja
Authors: Rosa Susanti  , Nina Sri
Published: July 2023

Latar belakang: Masa remaja merupakan masa transisi antara masa kana-kanak dan masa dewasa dimana kondisi kesehatan dimulai saat remaja perempuan ditandai dengan haid pertama dan pada remaja laki-laki ditandai dengan mimpi basah. Permasalahan kesehatan reproduksi remaja sangat berkaitan dengan perilaku remaja yang bersesiko yaitu diantaranya adalah perilaku merokok, minum yang mengandung alkhohol, penggunaan narkoba serta melakukan hubungan seksual sebelum menikah.

Tujuan: Penelitian ini bertujuan untuk mengetahui hubungan Pengetahuan Kesehatan Reproduksi, dan Sumber informasi Terhadap Sikap Remaja Dalam  Upaya Pencegahan Kehamilan Remaja.

Metode: Penelitian ini menggunakan pendekatan kuantitatif desain cross sectional. Dengan responden sebanyak 37 orang siswa/I yang menjabat sebagai pengurus OSIS. Penelitian dilakukan pada September 2022. Analisis dilakukan menggunakan uji chi square untuk menguji hubungan signifikan antara variabel pengetahuan dan Sumber informasi Terhadap variable Sikap.

Hasil: Hasil penelitian diketahui P value 0.005 yang berarti terdapat hubungan yang signifikan antara pengetahuan Terhadap Sikap Remaja Dalam  Upaya Pencegahan Kehamilan Remaja dengan OR 9,500 artinya responden yang memiliki pengetahuan yang tinggi mempunyai peluang 9,500 kali untuk memiliki sikap yang positif Dalam  Upaya Pencegahan Kehamilan Remaja.

Kesimpulan: Dari hasi penelitian ini diketahui bahwa tidak terdapat hubungan yang bermakna antara Pengetahuan Kesehatan Reproduksi, dan Sumber informasi Terhadap Sikap Remaja Dalam  Upaya Pencegahan Kehamilan Remaja. Diharapkan di sekolah mengadakan penyeluhan tentang kesehatan khususnya tentang kesehatan reproduksi dan dibentuk konselor sebaya
Determinan Sosial Ekonomi Praktik Swamedikasi di Indonesia: Analisis Data Susenas 2019
Authors: Dian Pratiwi Andini  , Ascobat Gani
Published: July 2023

Latar Belakang: Swamedikasi adalah upaya mandiri yang dilakukan seseorang untuk mengobati dirinya sendiri saat mengalami keluhan penyakit. Tren swamedikasi meningkat di Indonesia.

Tujuan: Sebuah model dibangun untuk mengetahui determinan praktik swamedikasi di Indonesia.

Metode: Penelitian menggunakan data Susenas 2019 dengan 258.633 Orang sebagai sampel penelitian. Analisis regresi logistik dilakukan untuk mengetahui variabel sosial ekonomi yang signifikan terhadap praktik swamedikasi.

Hasil: Perilaku swamedikasi dilakukan oleh 73.49% orang dengan variabel determinan yang berhubungan secara signifikan antara lain usia 15-25 tahun (OR: 1,254; 95% CI: 1,209 â€“ 1,301), usia 26-65 tahun (OR: 1,254; 95% CI: 1,161 â€“ 1,230), jenis kelamin (OR: 1,059; 95% CI: 1,035 â€“ 1,085), tingkat pendidikan (OR: 0,885; 95% CI: 0,866 â€“ 0,904), status perkawinan (OR: 0,948; 95% CI: 0,927 â€“ 0,970), status bekerja  (OR: 1,151; 95% CI: 1,128 â€“ 1,175), status merokok (OR:1,352; 95% CI: 1,316 â€“ 1,387), status kepemilikan jaminan kesehatan (OR:1.487; 95% CI: 1,456 â€“ 1,519), status lokasi tempat tinggal (OR: 1,032; 95% CI: 1,012 â€“ 1,050), akses teknologi informasi (OR: 1. 074; 95% CI: 1,031 â€“ 1,079) dan status ekonomi.

Kesimpulan: Usia, jenis kelamin, status pendidikan, status perkawinan, status merokok, lokasi tempat tinggal, status bekerja, status kepemilikan asuransi kesehatan, status akses teknologi informasi dan status ekonomi berpengaruh signifikan terhadap keputusan individu melakukan praktik swamedikasi. Determinan tidak memiliki jaminan kesehatan menjadi faktor yang paling mempengaruhi praktik swamedikasi.
Penguatan Gerakan Keluarga Sehat melalui Posyandu terhadap Pencegahan Stunting di Wilayah Kerja Puskesmas Paringgonan Kabupaten Padang Lawas
Authors: Saiful Bahri Halomoan Hasibuan  , Anto J. Hadi  , Rusdiyah Sudirman Made Ali  , Sukri Palluturi  , Namora Lumongga Lubis
Published: July 2023

Latar belakang: Stunting menjadi salah satu masalah kesehatan di Indonesia. Stunting merupakan indikator, kekurangan gizi kronis akibat ketidak cukupan asupan makanan dalam waktu yang lama.

Tujuan: Penelitian ini bertujuan untuk menganalisis penguatan gerakan keluarga sehat melalui posyandu terhadap pencegahan stunting.

Metode: Jenis penelitian kuantitatif dengan desain cross sectional study. Populasi dan sampel adalah seluruh keluarga keluarga yang ada di wilayah Kerja Puskesmas Paringgonan Kabupaten Padang Lawas sebanyak 68 keluarga dengan teknik pengambilan sampel secara purposive sampling serta uji statistik menggunakan chi-square dan regresi logistik.

Hasil: Hasil peneltian diperoleh bahwa program KB (p=0,001), ASI ekslusif (p=0,001), Keluarga mempunyai akses air bersih (p=0,001) adalah variabel yang berhubungan dengan kejadian stunting, sedangkan variabel anggota keluarga tidak ada yang merokok (p=0,193), persalinan di fasilitas kesehatan (p=0,102), status imunisasi (p=0,358), dan ASI ekslusif (p=0,358) tidak berhubungan dengan kejadian stunting. Selain itu variabel yang paling berhubungan dengan kejadian stunting adalah  ASI ekslusif dengan nilai Exp (B)= 20,954.

Kesimpulan: Program KB, ASI eksklusif, mempunyai akses air bersih merupakan faktor penyebab stunting. Sehingga diperlukan pendekatan kesehatan yang berkelanjutan berupa edukasi gizi keluarga dalam penguatan keluarga sehat dalam mencegah kejadian stunting.
Faktor yang Mempengaruhi Tingkat Kepercayaan Masyarakat terhadap Vaksin Covid-19 di Kecamatan Padangsidimpuan Selatan
Authors: Muhammad Amin Ritonga  , Haslinah Ahmad  , Abdul Majid
Published: July 2023

Latar belakang: Program vaksinasi dianggap sebagai kunci dalam mengakhiri pandemi karena dapat digunakan dalam rangka mengurangi angka morbiditas dan mortalitas serta membentuk kekebalan kelompok terhadap virus Covid-19.

Tujuan: Tujuan penelitian ini adalah untuk mengetahui faktor yang mempengaruhi tingkat kepercayaan masyarakat terhadap vaksin covid 19 di kecamatan Padangsidimpuan Selatan.

Metode: Jenis penelitian adalah kuantitatif dengan menggunakan cross section study. Populasi adalah seluruh masyarakat yang ada di wilayah kecamatan padangsidimpuan sebanyak 71.505 jiwa. Sampel penelitian sebanyak 397 dengan menggunakan rumus slovin. Teknik pengambilan sampel menggunakan teknik purposive sampling.

Hasil: Penelitian menunjukkan bahwa variabel pengetahuan (p=0,000), sikap (p=0,000) dan riwayat covid 19 (p=0,000) adalah variabel yang berhubungan dengan kepercayaan vaksin. Variabel pendidikan (p=0,632) dan jenis kelamin (p=0,175) tidak berhubungan dengan kepercayaan vaksin serta riwayat covid 19 yang paling berhubungan dengan kepercayaan vaksin dengan nilai Exp (B)=7,883.

Kesimpulan: Orang yang mempunyai riwayat covid 19 memiliki tingkat kepercayaan 7,883 kali lebih percaya dari pada orang yang tidak mempunyai riwayat covid 19 dan untuk pemerintah daerah agar melakukan sosialisasi terhadap penyebaran vaksin.
Faktor yang Berhubungan dengan Kejadian Anemia pada Ibu Hamil di Puskesmas Rawat Inap Batangtoru Kabupaten Tapanuli Selatan
Authors: Yuli Arisyah Siregar  , Haslinah Ahmad  , Anto J. Hadi
Published: July 2023

Latar belakang: Anemia pada masa kehamilan merupakan masalah kesehatan ibu dan anak. Temuan di Indonesia menunjukkan 90 persentase anemia pada kehamilan disebabkan karena kekurangan zat besi (Fe). Oleh karena itu anemia gizi pada masa kehamilan sering diindentikkan dengan anemia gizi besi.

Tujuan: Penelitian ini bertujuan untuk menilai faktor berhubungan dengan kejadian anemia pada ibu hamil di Puskesmas Rawat Inap Batangtoru Kabupaten Tapanuli Selatan.

Metode: penelitian ini menggunakan metode observasional dengan pendekatan cross sectional study, Penelitian ini dilakukan di Puskesmas Rawat Inap Batangtoru Kabupaten Tapanuli Selatan dan pelaksaan penelitian ini pada bulan Novemberâ€“ Februari 2023. Populasi dan sampel penelitian ini adalah seluruh ibu hamil di Puskesmas Rawat Inap Batangtoru  Kabupaten Tapanuli Selatan tahun 2022 sebanyak 82 ibu hamil dengan teknik pengambilan sampel exhaustive sampling. Instrumen penelitian yang digunakan adalah kuesioner data identitas dan riwayat kesehatan responden serta analisis data menggunakan uji chi-square dan regresi logistik.

Hasil: Hasil penelitian di peroleh bahwa penyakit infeksi (p=0,001), suplementasi tablet Fe (p=0,001), status ekonomi (p=0,001) berhubungan dengan kejadian anemia pada ibu hamil dan variable yang paling berhubungan adalah penyakit infeksi dengan nilai Epx (B)=0,872.

Kesimpulan: Penelitian ini disimpulkan bahwa ibu hamil mengalami anemia disebabkan oleh factor penyakit infeksi, suplementasi tablet Fe dan status ekonomi, sehingga perlu dilakukan edukasi makanan bergizi yang mengandung zat besi.
Analisis Spasial Kejadian Diare pada Balita di Provinsi Sumatera Utara Tahun 2020
Authors: Plate Renata Philipa , Herdayati Milla
Published: July 2023

Latar belakang: Provinsi Sumatera Utara memiliki prevalensi diare pada balita paling tinggi di Indonesia. Kejadian diare pada balita berhubungan dengan faktor risiko individu dan lingkungan yang saling berinteraksi dalam ruang spasial.

Tujuan: Untuk mengetahui faktor resiko, pola spasial, dan wilayah prioritas intervensi diare pada balita di Sumatera Utara.

Metode: Penelitian memiliki desain studi ekologi. Faktor risiko diare pada balita ditentukan dengan korelasi Pearson. Global Moran digunakan untuk mengetahui dependensi spasial dari insiden diare pada balita, sedangkan LISA (local indicators of spatial association) digunakan untuk mengidentifikasi wilayah prioritas intervensi.

Hasil: Terdapat hubungan positif yang signifikan antara insiden diare pada balita dengan persentase rumah tangga tanpa jamban sendiri. Pola spasial insiden diare pada balita di Sumatera Utara membentuk pola berkelompok. Terdapat tujuh daerah prioritas utama intervensi yang terbagi ke dalam dua klaster. Klaster pertama terletak di bagian tengah menuju timur (4 wilayah), klaster kedua terletak di bagian selatan (3 wilayah).

Kesimpulan: Upaya pencegahan diare pada balita dilakukan dengan pembangunan jamban keluarga dan edukasi pentingnya kepemilikan jamban, terutama bagi penduduk yang tinggal di wilayah prioritas intervensi.
Salivary Biomarkers in the Diagnosis of Sjogren’s Syndrome: A Review of Current Research Progress
Authors: Li Siting , Zheng Haotian , Guan Jing
Published: July 2023

Saliva contains a variety of biomarkers, which are closely related to the occurrence, progression, diagnosis and treatment of oral and systemic diseases. Currently, the diagnosis of Sjögren’s syndrome (SS) still relies on invasive salivary gland biopsy procedures and serum Ro-52/SSA and La/SSB testing, which often makes early diagnosis extremely difficult, so screening for specific saliva biomarkers is extremely beneficial in the diagnosis and individualized treatment of Sjögren’s syndrome. This article elaborates the research progress of Sjogren’s syndrome-related biomarkers in saliva, in order to provide new methods and ideas for the early diagnosis of Sjogren’s syndrome.
Machine Learning-based Prediction of the Likelihood of Colorectal Cancer Using miRNA Expression
Authors: Sultan Aamer , de Asa Aaron Austin , Guimbangunan Tesah Mae , Serapio Ezekiel Dmitri , Fellizar Allan , Albano Pia Marie , Tomas Rock Christian
Published: July 2023

[Background] Colorectal cancer (CRC) comprises 10% of all cancer diagnoses, making it the third most diagnosed cancer globally. Despite its prevalence, most current methods for identifying CRC lack sensitivity and consistency while being invasive and costly. Thus, this study aimed to develop artificial neural network (ANN) models that could accurately detect CRC using miRNA expressions in tissue and plasma samples. [Methods] The study used miRNA expression profiles of formalin-fixed paraffin-embedded tissue and plasma samples obtained from CRC patients and healthy controls. ANNs were trained to discriminate between CRC patients from healthy controls using the relative expression of miR-21-5p, miR-196b-5p, miR- 135b-5p, miR-92a-3p, miR-29a-3p, and miR-197-3p in colorectal tissues and blood plasma. Multivariate logistic regression (MLR) and decision tree (DT) models were used to compare the performance of the ANN models. [Results] The ANNs achieved an accuracy of 98.5 and 88.2%, a sensitivity of 90.9 and 80.4%, a specificity of 92.6 and 84.7%, and an area under the ROC curve of 0.92 and 0.83 for the plasma and tissue samples, respectively. Moreover, sensitivity analysis of the ANN models showed that miR-135b-5p and miR-92a-3p had the greatest influence in distinguishing CRC from healthy plasma and malignant from neoplasm-free colorectal tissues, respectively. However, only miR-135b-5p was significantly downregulated in both CRC plasma and malignant colorectal tissue samples. Results from the MLR and DT models support the results from the ANN sensitivity analysis. [Conclusion] Our results show that the trained ANNs were able to accurately and confidently detect CRC using the considered six miRNA expression levels in colorectal tissue and plasma samples, providing an accurate, rapid, and less-invasive approach to diagnosing CRC.
Contribución al conocimiento de la biología de los pulgones de cereales y de la epidemiología del virus del enanismo amarillo de la cebada (BYDV) en la zona de regadío de Lleida
Authors:   , Comas Angelet Jordi
Published: July 2023

En la zona de regadio de Lleida, los pulgones de cereales Rhopalosiphum padi (l.) y Sitobion avenae (f.) permanecen a lo largo de todo el año en gramineas cultivadas en la zona; cereales forrajeros, cereales de invierno y maíz.

El solapamiento de los ciclos de estos cultivos permite el paso de los pulgones alados de uno a otro. en condiciones mediterráneas la temperatura solo puede explicar parte de la dinámica de poblaciones de estas especies durante el invierno y principios de primavera.

El déficit hídrico en el cultivo, durante este periodo, tiene un efecto indirecto importante sobre la actividad de estas especies a través del efecto que tiene sobre la fisiología del cultivo, y constituye un factor determinante en la dinámica de poblaciones.

Se han detectado aislados de BYDV tipo PAV, MAV y RPV.

En los cereales de invierno el porcentaje de muestras positivas con el antisuero tipo MAV es relativamente elevado y se mantiene bastante estable de año en año, el del aislado tipo PAV es mucho más variable, y el del aislado tipo RPV es muy bajo. En el maíz destaca el elevado porcentaje de muestras positivas con el antisuero tipo MAV, siendo el de los aislados tipos RPV y PAV muy inferior, especialmente la de este ultimo. Finalmente en los cereales forrajeros, y también en el ricio de cereales, los aislados predominantes son tipo PAV y MAV.

Los alados de R. padi y de S. avenae que van de un cultivo a otro permiten que el inoculo de BYDV pueda pasar de cultivo a cultivo y por tanto, permiten que este se pueda mantener a lo largo de todo el año en dicha zona, especialmente el aislado tipo MAV. La dispersión del aislado tipo PAV esta fundamentalmente condicionada a R. padi, ya que S. avenae -debido a la gran incidencia del aislado tipo MAV- no transmite de una forma eficiente el aislado tipo pav. Es de destacar la relativamente elevada eficiencia de R. padi en la transmisión del aislado tipo MAV, principalmente en infecciones.
Analisis Metode Pembelajaran yang Efektif pada Materi SKI Kelas XI di MAN 1 Surakarta Tentang Pembaharuan Islam di Indonesia
Authors: Nur Dewanti Oktaviana
Published: July 2023

This study aims to analyze effective learning methods on Islamic Cultural History (SKI) material in class XI at MAN 1 Surakarta about Islamic Renewal in Indonesia. The literature study method was used in this study by collecting and analyzing various literature related to learning methods that are relevant to the material. The results of the analysis show that the discussion method and the case study method can be effective alternative learning methods in presenting material on Islamic renewal in Indonesia to students. The discussion method can facilitate interaction between teachers and students, as well as between students, which can encourage students to think critically and be active in the learning process. The case study method can link theory with concrete practice and help students explore information about the context, factors, and impact of Islamic renewal through case study analysis. However, the use of learning methods must be adapted to the characteristics of students, learning objectives, and available resources in the MAN 1 Surakarta environment. Evaluation and adjustment of the learning methods applied are also important to ensure the effectiveness and sustainability of the learning process. This study provides recommendations to teachers or other educational institutions to use discussion and case study methods as an alternative effective learning method in presenting material on Islamic renewal in Indonesia to students. This conclusion is based on an analysis of literature studies and further research is needed with a more comprehensive method to strengthen the results of this study.
Eksistensi Aspek Teknologi dalam Pembuatan Akta Autentik Secara Elektronik pada Pengaturan Jabatan Notaris di Era Industri 5.0
Authors: Irawan Ade , Ryan Bakry M. , Hardian Frengki
Published: July 2023

This study describes the concept of the existence of technological aspects and the form of regulation of the office of notary in the technology-based industrial era 5.0 in making authentic deeds electronically (cyber notary), with a doctrinal legal research method using a statutory approach and a conceptual approach made from primary, secondary, tertiary law with qualitative analysis. The results of this study state that the existence of technological aspects in making notarial authentic deeds in the industrial era 5.0 conceptually needs to be made an integrated notary system in the form of a digital application (platform) integrated with various institutions/ministries, so that the reading of deeds, fingerprints and signatures of various parties can be done digitally and real time validation of documents that are the basis for making the deed until the form of notarial deed is paper less (without paper media). Thus, the form of regulation of the office of notary in the era of technology-based industry 5.0 in making authentic deeds must be able to answer and respond to various developments and changes in social dynamics in society. To meet legal needs, the legislators need to realize progressive law.
Perlindungan Hukum Terhadap Pekerja Anak yang Dieksploitasi Di Kota Kupang
Authors: Minata Hamid Mira , Ramlah Usman Siti , Fransiska Pello Helsina
Published: July 2023

Pekerja anak menurut hukum Perdata yang berlaku di Indonesia dapat dipahami bahwa anak adalah seseorang yang umurnya dibawah 18 (delapan belas) tahun sehingga anak yang dibawah umur 18 (delapan belas) tahun tidak dapat dikatakan cakap hukum dan perbuatan yang dilakukuannya belum mencapai kriteria perbuatan atau tindakan hukum. Dalam dunia kerja tentunya harus ada tindakan hukum yang dilakukan berupa perjanjian atau kontrak kerja mencapai kriteria perbuatan atau tindakan hukum. Dalam dunia kerja tentunya harus ada tindakan hukum yang dilakukan berupa perjanjian atau kontrak kerja. Metode penelitian yang digunakan yaitu dalam penelitian ini adalah penelitian hukum empiris. Adapun sumber dan jenis data dalam penelitian ini adalah data primer yang diperoleh dari hasil studi lapangan dengan wawancara. Data sekunder diperoleh dari studi kepustakaan. Data yang diperoleh kemudian diolah dengan cara memeriksa dan mengoreksi data. Setelah data diolah kemudian dianalisis secara kualitatif. Berdasarkan hasil penelitian dan pembahasan menunjukan bahwa upaya perlindungan yang dilakukan pemerintah bertujuan untuk mencegah dan menghentikan terjadi eksploitasi anak, seperti melakukan sosialisasi dan pembinaan kepada anak-anak remeja dan masyarakat tentang pemahaman perlindungan hukum terhadap eksploitasi pekerja anak dan bahaya eksploitasi anak Pemerintah Seperti Dinas tenaga kerja dan transmigrasi Provinsi NTT, UPTD PPA Provinsi NTT, PPKS PPTKIS, PL dan pihak kepolisian sebagai gugus tugas pelepasan terakhir untuk mencegah terjadinya eksploitasi anak. Selain itu Faktor-factor penghambat perlindungan hukum terhadap pekerja anak yaitu Peraturan-peraturan yang ada masih di rasakan belum terlaksana secara maksimal, Kesulian untuk menagkap dan menjerat pelaku/ oknum-oknum yang di duga melakukan eksploitasi anak kurang kesadaran orang tua terhadap eksploitasi anak.
NEEDS ANALYSIS OF HALAL MATCHMAKING FOR MUSLIM MARRIAGE IN JAPAN
Authors: Sugimoto Kyoichiro , Betania Kartika Muflih  , Hamzah Mohd. Salleh  , Mira Kartiwi
Published: July 2023

Today, halal matchmaking services, such as halal apps and halal speed dating have appeared in many Muslim and non-Muslim countries. It is important that Muslims not only marry in a halal manner, but also maintain a healthy family life after marriage. However, in Japan, where Muslims are almost invisible minority, there are no services that provide halal matchmaking including pre-marriage education based on Maqasid al-Shariah. The purpose of the research is to analyze the need for halal matchmaking services in Japan. Halal matchmaking needs of single and divorced Muslims are to be determined. Methods: The researcher recruited potential participants for a halal matchmaking through social media of Chiba Islamic Cultural Center from 25 July to 21 August 2022. Single and divorced Muslims living in Japan who were able to communicate adequately in Japanese, were purposively selected for in-depth interviews. Feedback was obtained through in-depth interviews with all the participants after the halal matchmaking. Findings: 111 people registered their personal profiles. There were 109 valid answers (98.1%). Forty-one people responded for the preliminary interviews. Twenty people who attended the matchmaking were invited for the feedback in-depth interviews. Barriers to find a potential marriage partner among Muslims in Japan include a rarity of Muslims as a user of the Japanese matchmaking services, time and money consuming efforts and anxiety for marriage due to the lack of trust or assurance of individualistic marriage compared to that of communal marriages. Thus, community effort to develop halal matchmaking is needed for the Muslims in Japan.
Epidemiología de la COVID-19 en Honduras, 10 de marzo 2020-10 de marzo 2021.
Authors: Rivera Ana` Carolina , Mendizábal Solé Renata , Enamorado Juan Alberto
Published: July 2023

Introducción :El objetivo del estudio fue describir las características epidemiológicas de los casos y fallecimientos por COVID-19 durante el primer año de pandemia en Honduras. Población y métodos: Realizamos un análisis descriptivo de los datos de vigilancia de las defunciones y casos confirmados de COVID-19 notificados a la Secretaría de Salud de Honduras durante el período 10-3-2020 a 10-3-2021. Usamos la razón de riesgos (RR) y su intervalo de confianza (IC) del 95%. Resultados: En el primer año, se confirmaron 175,271 casos de COVID-19 (tasa de incidencia notificada de 1,883.7 por 100,000 habitantes. El riesgo de morbilidad más alto ocurrió en mayores de 40 años y no hubo diferencia en las tasas por sexo. La tasa de mortalidad de 46.4 por 100,000 habitantes y sus patrones fueron diferentes: se incrementó drásticamente con la edad, llegado entre personas de 80+ años a 539.7 veces la de los menores de 20 años (RR de mortalidad= 539.7; IC 95% = 390.6, 745.7). El riesgo de mortalidad entre masculinos fue 1.7 veces sus contrapartes (RR de mortalidad = 1.7, IC 95% = 1.6, 1.8). La mayor ocurrencia de morbilidad y mortalidad fue en municipios de grandes ciudades aquellos con destinos turísticos. La mayoría de las defunciones (70.6%) por COVID-19 ocurrieron entre personas con alguna comorbilidad. Discusión: En Honduras el mayor riesgo de COVID-19 lo experimentaron los adultos mayores, particularmente aquellos con comorbilidades. Las medidas de prevención se orientaron a la población y áreas de riesgo identificadas en este estudio.
virtual fourfold
Authors: Swer Gregory , Du Toit Jean
Published: July 2023

Daniel O’Shiel recently identified four categories of virtuality, which he terms “real virtualities”, that are perpetually present in human perception. These virtual horizons (Self, World, Others, and Values) continuously structure our experience without themselves being directly experienced. This essay argues that O’Shiel’s four categories of the virtual correspond strongly to the concept of the Fourfold found in the writings of the later Heidegger, and that Heidegger’s Fourfold can be fruitfully understood as a phenomenological framework of the virtual.