bluuebunny/crossref_metadata_2025 huggingface dataset:
Algorithm for early detection of a high risk of speech sound disorders in children
Authors: Grudziąż-Sękowska Justyna , Olczak-Kowalczyk Dorota , Zadurska Małgorzata
Published: January 2019

Anatomical defects and functional disorders of the masticatory system are often accompanied by speech sound disorders. Speech therapy prophylaxis, as well as prevention of disorders of all parts of the masticatory system, is focused on monitoring of the proper development of anatomy and functions typical of a given developmental period. An early therapeutic intervention is associated with better results. Aim. This study aimed to create a simple tool for dentists to assess the risk of articulation disorders using several preselected physical and functional characteristics. Materials and methods. Three hundred children aged 7-10 years had a dental and speech examination performed. Using the CHAID algorithm upon assessing the disorders of the masticatory system and coexisting speech sound disorders, it was possible to create a decision tree to determine the probability of two disorders occurring at the same time. Results. It was observed that there were many correlations between individual anatomical or functional disorders and presence of speech sound disorders. The strength of those correlations was measured. Mesioclusions, distoclusions, open bites, short lingual frenulum, persistent infantile swallow pattern, mouth breathing, and premature loss of deciduous teeth were all determined to increase the risk of speech sound disorders in children. Conclusions. This algorithm is a simple diagnostic tool for dentists. It enables early detection of a high risk of speech sound disorders. Children with particular malocclusions should undergo speech therapy prophylaxis and be referred to consultations with a speech therapist. Early detection of such abnormalities will allow to avoid not only the intensification and consolidation of speech defects, but also certain pathologies of the oral cavity. (Grudziąż-Sękowska J, Olczak-Kowalczyk D, Zadurska M. Algorithm for early detection of a high risk of speech sound disorders in children. Orthod Forum 2018; 14: 119-29).
Sturge-Weber syndrome
Case report
Authors: Witanowska Joanna , Laskowska Małgorzata , Zadurska Małgorzata
Published: January 2019

Sturge-Weber Syndrome (SWS – encephalotrigeminal angiomatosis) is a rare non-hereditary congenital condition. It develops in the early foetal period, at the stage when the embryo head is being formed, as a result of a random somatic mutation of the GNAQ gene due to unknown reasons. The main symptom is the formation of congenital angiomas, especially in the area of capillaries, in the leptomeninges in the brain, and along the course of the trigeminal nerve. Such angiomas may also be present on lips, and in the whole oral cavity: on its bottom, palate and gingivae. It may lead to serious malocclusions and breathing problems. Aim. This article aims to present problems regarding orthodontic treatment of patients with Sturge-Weber syndrome, using an example of a 7-year-old female patient. Case report. A 7-year-old girl with all signs of this syndrome, namely glaucoma, epilepsy, neurological disorders, cutis marmorata telangiectatica congenita and after sanitation of the oral cavity, had hygiene procedures and exercises with a vestibul plate introduced. Two attempts to take impressions for appliances failed due to patient’s anxiety reactions. Conclusions. This case shows difficulties that may be faced by an orthodontist when treating patients with Sturge-Weber syndrome. In this case, namely type I in the Roach scale, due to neurological disorders it was necessary to take special precautions in relation to procedures introduced and to avoid stress in a patient. It makes orthodontic treatment difficult. (Witanowska J, Laskowska M, Zadurska M. Sturge-Weber syndrome. Case report. Orthod Forum 2018; 14: 143-9).
Orthodontic management in a female patient with an impacted incisor in the mandible – case report
Authors: Świątkowska Agnieszka , Dunin-Wilczyńska Izabella , Świątkowski Wojciech
Published: January 2019

Traumas to deciduous teeth, such as intrusion and complete avulsion, lead to the most severe injuries to tooth buds of permanent teeth. The most common post-traumatic complications of permanent teeth include: enamel hypoplasia or hypocalcification, crown or root dilaceration, partial or complete inhibition of root growth, and eruption disorders. Aim. The paper aimed to present orthodontic treatment in a female patient with an impacted permanent lower incisor with significantly impaired morphology due to a trauma to its deciduous predecessor. Material. Material included: patient’s orthodontic records, gypsum models, photographs and radiological records. Results. Orthodontic treatment was successful despite abnormal morphology of the impacted tooth 41. After 4-year follow-up the tooth remains in the arch. Conclusions. A tooth can be preserved in the socket when the crown-to-root ratio (CRR) is at least 1 : 1. In this case, CRR for the tooth 41 was 2 : 1, and therefore its extraction would be recommended. Despite this a decision was made to introduce an impacted tooth into the arch. Thanks to its presence in the dental arch it was possible to preserve appropriate bone quality for implantation of a prosthetic implant in the future. Prosthetic treatment (if necessary) may be performed after completion of vertical growth of the face that is observed in women after the age of 16 years. Summary. This case of a 15-year female patient shows that as a result of orthodontic and surgical intervention and despite significant root shortening the tooth may remain in the dental arch and play its functional and aesthetic role. (Świątkowska A, Dunin-Wilczyńska I, Świątkowski W. Orthodontic management in a female patient with an impacted incisor in the mandible – case report. Orthod Forum 2018; 14: 150-7).
Laser treatment with 625 Inconel powder
of hot work tool steel using fibre laser
YLS-4000
Authors: Dobrzański L.A. , Jonda E. , Pakieła W. , Dziekońska M.
Published: January 2019

Purpose: The purpose of this investigation was to determine the changes in the surface
layer (Inconel 625), obtained during the laser treatment of tool-steel alloy for hot work by the
use high-power fibre laser.
Design/methodology/approach: Observations of the layer structure, HAZ, and substrate
material were made using light and scanning microscopy. The composition of elements
and a detailed analysis of the chemical composition in micro-areas was made using the
EDS X-ray detector. The thickness of the resulting welds, heat affected zone (HAZ) and the
contribution of the base material in the layers was determined.
Findings: As a result of laser cladding, using Inconel 625 powder, in the weld overlay microstructure
characteristic zones are formed: at the penetration boundary, in the middle of weld overlay and
in its top layer. It was found that the height of weld overlay, depth of penetration, width of weld
overlay and depth of the heat affected zone grows together with the increasing laser power.
Practical implications: Laser cladding is one of the most modern repair processes for
eliminating losses, voids, porosity, and cracks on the surface of various metals, including
tool alloys for hot work. Laser techniques allow to make layers of materials on the repaired
surface, that can significantly differ in chemical composition from the based material
(substrate material) or are the same.
Originality/value: A significant, dynamic development in materials engineering as well as
welding technologies provides the possibility to reduce the cost of production and operation
of machinery and equipment, among others by designing parts from materials with special
properties (both mechanical and tribological) and the possibility of regeneration of each
consumed element with one of the selected welding technologies.
ALGUNAS CONSIDERACIONES CRÍTICAS SOBRE EL PROBLEMA DE LA MÍMESIS ARTÍSTICA EN ADORNO Y LUKÁCS
Authors: Orlante Emiliano
Published: January 2019

Este ensayo analiza una de las polémicas más trascendentales en el campo de la estética del siglo XX del denominado marxismo occidental: Adorno – Lukács. Si bien esta contienda ha sido tratada desde diversos enfoques teóricos y políticos, la crítica especializada ha desatendido los alcances de la categoría de mímesis dentro de esta confrontación filosófica. De hecho, la mayoría de los trabajos que abordan este problema estético toman por algo dado la relación de igualdad que Adorno hizo entre la teoría del reflejo de Lukács y el realismo socialista estalinista. Por esta razón, nuestra investigación se propone rastrear, en estos pensadores, el concepto de mímesis para luego analizarlo a partir de sus relaciones con otras categorías relevantes de la estética. En este derrotero, estudiaremos algunos conceptos de la estética de Heidelberg para cotejarlos con las categorías estéticas empleadas por Adorno. Una vez extraídas nuestras primeras ideas, pasaremos a indagar los fundamentos filosóficos y métodos de análisis de sus postulados estéticos. Finalmente, a la luz de nuestra pesquisa, intentaremos contribuir al debate con una nueva propuesta, que trate de dilucidar, a su vez, si las resonancias y desencuentros políticos, derivados de la equiparación entre teoría del reflejo y realismo socialista, pueden sostenerse desde el análisis filosófico de las categorías estéticas vinculadas con la mímesis.
TEORIAS DA JUSTIÇA PÓS-RAWLS: UMA ANÁLISE COMPARADA ENTRE O MODELO IGUALITÁRIO DE RONALD DWORKIN E AMARTYA SEN
Authors: Costa Thais Cristina Alves
Published: January 2019

Trata-se da comparação entre dois modelos de justiça influenciados pelas ideias políticas de Jonh Rawls, a saber: a igualdade de recursos de Ronald Dworkin e a igualdade de capacidades de Amartya Sen. Com o intuito de apresentar as principais semelhanças e diferenças desses dois sistemas em relação à proposta rawlsiana, utilizaremos como fio condutor as obras Sovereign Virtue: the Theory and Practice of Equality de Dworkin e Development as freedom de Sen. Através desse comparado será possível apreender como esses dois filósofos conseguiram aperfeiçoar a proposta igualitária engendrada por John Rawls.
IDENTIDADE DO HOMEM MODERNO: DIGNIDADE OU DEGENERAÇÃO? UMA INVESTIGAÇÃO ACERCA DO SOFRIMENTO EM CHARLES TAYLOR E NIETZSCHE
Authors: Alvarenga Junnior Neto Francisco
Published: January 2019

A questão que pretende-se norteadora deste texto direciona-se à igualdade metodológica entre o pensamento de Charles Taylor e Nietzsche, bem como suas diferentes compreensões acerca da construção do edifício moral. Daquilo que torna próximas as duas expressões filosóficas, certamente é possível pontuar a leitura histórica à que os dois se propõem realizar. Entretanto, enquanto em Taylor o que se pretende, com certa relevância, principalmente em seu livro As fontes do Self, é, por meio de uma hermenêutica genealógica, aclarar as fontes da moral que prefiguram a relação entre identidade e bem na modernidade, em Nietzsche a busca pela origem da moralidade assume uma posição negativa e aponta para a decadência do homem. Diferente de Taylor que viu em tal negação as raízes da dignidade do homem moderno, Nietzsche concebe essa relação como degeneração de tudo que é grande no homem, que só é possível a partir da afirmação não só do belo, mas, também, do feio e do sofrimento, compreendendo-o como instante de possibilidade de um vir-a-ser maior.
Design de Visualizações Narrativas Interativas
Authors: Queiroz Santos Caroline , Selbach Silveira Milene
Published: January 2019

Narrative visualization is an emerging data visualization field and has been used for the purpose of communicating information efficiently and intuitively as well as providing greater engagement in data exploration. In this mini-course, we will present and discuss fundamental concepts for interactive narrative visualizations design, and explore these concepts - in theory, and practice - by means of a model that aims to enable reflection on decisions to be taken in narrative visualization’s design.
Desafios na potencialização de uma cultura ágil de inovação centrada no usuário: relato de experiência na tecnologia educacional do SAS Plataforma de Educação.
Authors: Fontenele Adriana , Oliveira Deivith
Published: January 2019

Este artigo apresenta o relato dos principais desafios culturais, organizacionais e técnicos enfrentados pelo setor de Tecnologia Educacional da empresa SAS Plataforma de Educação na potencialização de uma cultura ágil de inovação centrada no usuário. Tendo raízes no mercado editorial, hoje a empresa posiciona a Tecnologia Educacional como um dos pilares de valor para seus clientes de todo o Brasil. Para além da visão de ser a melhor plataforma de educação do país, o setor de tecnologia tem como objetivo contribuir com o desenvolvimento da comunidade local de profissionais, como refletido nas intervenções realizadas no setor durante o primeiro semestre de 2018 frente aos desafios levantados.
Um estudo da experiência dos usuários de Internet banking de um banco público brasileiro
Authors: Hellen Oliveira da Silva Thiago , Da Silva Juliani Jeferson , Soares Mendes Marília , Rosemberg Maia de Carvalho Carlos
Published: January 2019

Banking systems have been a frequent concern between customers and companies, since the number of financial transactions carried out by the Internet has increased considerably. This study investigated the experience of internet banking users of a Brazilian bank. Techniques such as interviews, access log analysis, user journeys and usability testing were applied to identify the elements of the user experience using a generic model. From the studies carried out, it was verified that the characteristic users of the service had difficulty or are unable to use all the essential services of internet banking and are necessary design improvements of current interface.
Ambiente de Treinamento de Acompanhantes de Portadores de Transtorno Espectro Autista em Realidade
Authors: Pina Soares Thiago , Antonio P. de Souza Marco , B. Marques Leonardo , C. Monteiro Dionne
Published: January 2019

With the technological advancement of the last decade, the use of technology to help and assist in different areas of study, such as medicine, physiotherapy, psychology, etc., is remarkable, since it allows more specific and detailed information for its study, which facilitates the analysis of results. Virtual Reality (VR) is an example of technology that continues to grow in the last decades and has become popular among these areas of study due to its great potential to provide a virtual immersion environment that can simulate any situation and also has the possibility of generate results that can be compared to actual results.
A Non-Conventional Interaction on Computational Systems Based on Mouth Puffing
Authors: M. Campos Erick , A. Freitas Alexandre , F. Cunha Renan , T. Batista Cassio , S. Meiguins Bianchi , C. Sampaio Neto Nelson
Published: January 2019

Computer mice and keyboards have for long been the dominant input devices for desktop computers. Nonetheless, they still represent quite a barrier — especially for people whose upper-limb motor skills are compromised. This work proposes a low-cost, mouth-puffing-based device that is able to perform the mouse click on computational platforms. Additionally, a driver was developed to allow the device to communicate with the computer via audio jack P2 interface. The mouse cursor is controlled by head tracking thanks to eViacam software. The evaluation took place by comparing the proposed equipment with the dwell time method on navigation tasks elaborated over websites.
Interfaceando com o Espectro Autista
Authors: Renata M. Gobbo Maria , R. Sachs C. Barbosa Cinthyan , Mafort Fernanda
Published: January 2019

Crianças com Transtorno no Espectro Autista (TEA) apresentam, em algum grau, déficits na comunicação, comportamento e interação social. Jogos têm sido utilizados para ajudá-las nessas questões. Porém, pouca atenção é dada na alfabetização de crianças com TEA e isso reflete também nos jogos com esse propósito. Conceitos de acessibilidade e design interativo são deixados de lado na interação entre usuários autistas e tais aplicativos, o que acaba prejudicando a eficácia dos jogos, principalmente na questão da alfabetização. Este trabalho aborda o desenvolvimento de um jogo que foi criado não apenas para alfabetizar crianças no espectro autista, mas também para familiarizá-las com atividades de autocuidado e higiene pessoal (chamadas de Atividades de Vida Diária - AVDs), através de PECS (Pictures Exchange Communication System).
O Impacto da Notoriedade dos Usuários para a Imortalidade Digital
Authors: F. Galvão Vinícius , Maciel Cristiano , Viterbo José
Published: January 2019

No processo de investigação de como usuários respondem a imortalidade digital, uma nova forma de interação póstuma, um questionamento surgiu; a imortalidade digital deve ser tratada diferente entre famosos e não-famosos? Trabalhando com um grupo focal nós conseguimos encontrar fatores importantes que devem ser considerados ao immortalizar uma pessoa; e o quando e como é aceitável.
Redesign de aplicativos para pessoas com Transtorno do Espectro Autista orientado pelas diretrizes do GAIA
Authors: De Mendonça Bruno , J. Silva Lopes Carlos , S. Mendes Marília , Beatriz Marques Anna
Published: January 2019

Pessoas com o Transtorno do Espectro Autista (TEA) apresentam dificuldades na interação social, comunicação e um repertório restrito de interesses e atividades. Devido às dificuldades para entender expressões, as pessoas com TEA podem não compreender ou perceber determinados conteúdos, termos e imagens presentes na interface de aplicações. Pesquisas recentes propõem diretrizes para a construção de interfaces adequadas a esses usuários, como o GAIA (Guia de Acessibilidade de Interfaces Web com foco em aspectos do Autismo). Porém, ainda não existem relatos sobre o uso dessas diretrizes no redesign de interface de aplicações. Esse artigo apresenta a adoção das diretrizes do GAIA para o redesign de interface de dois aplicativos móveis para pessoas com TEA.
Hidrate Spark: Avaliando um Sistema Ubíquo para Motivar a Ingestão de Água
Authors: Cezar de Souza Filho José , Randel Freitas Brito Marcos , Raimundo Rocha Mendonça Antonio , Vitor Martins Marcos , Libório Sampaio Andréia
Published: January 2019

O objetivo do presente artigo é avaliar a usabilidade e a experiência do usuário do aplicativo ubíquo Hidrate Spark, desenvolvido para apoiar a ingestão diária de água. Para isso, um conjunto de métodos foi utilizado, a fim de enfrentar o desafio de avaliar a qualidade de uso de sistemas ubíquos. Os resultados mostram os problemas que podem prejudicar a interação do usuário com o aplicativo.
Como está o seu ciclo menstrual? Uma Avaliação de Comunicabilidade e Percurso Cognitivo do Aplicativo Clue
Authors: Engelmann Laura , Signoretti Ingrid , Prestes Matheus , Larréa Vivian , Silveira Milene
Published: January 2019

O controle de ciclo menstrual é uma das maiores dores de cabeça das mulheres. Saber quando foi a última menstruação, quando iniciou a cartela do anticoncepcional e quando é a janela de fertilidade são algumas das muitas preocupações do público feminino. Hoje, a abrangência do uso de smartphones e a quantidade de aplicativos que ajudam a gerenciar atividades diárias, trouxe consigo uma solução para os anseios das mulheres. Neste contexto, foi realizada a avaliação do aplicativo Clue, a fim de entender como ele auxilia no acompanhamento do ciclo menstrual. Para isto, foram utilizados dois métodos de avaliação: como método de inspeção foi utilizado o Percurso Cognitivo e como método de observação de uso foi utilizada a Avaliação de Comunicabilidade. Foi possível verificar que o aplicativo possui alguns problemas relacionados com a comunicação, mas que, de maneira geral, os usuários se mostraram satisfeitos com seu uso.
Aprendizagem Baseada em Projeto simulando o Método de Design Sprint: “5 dias” em um Semestre
Authors: Silva Prietch Soraia , Langstton Costa Alves Mickael
Published: January 2019

The goal of this paper is to present a brief report of the Human-Machine Interface course’ conduction, techniques used and some results delivered by students. The theme of application during the semester was “Engaged Communities”, according to the Call for Design Competition for Students of CHI’18. From competition’s instructions, we simulated Design Sprint sections, during one semester, as a strategy to organize design proposals and learning assessment.
O Uso de Práticas de IHC na Regionalização de um Aplicativo de Compartilhamento de Mensagens
Authors: Portela Carlos , Nascimento Elison , Monteiro Enio
Published: January 2019

O WhatsApp é um aplicativo que permite o compartilhamento de mensagens, sendo amplamente utilizado no Brasil e no mundo. Devido a internacionalização do seu público-alvo, o WhatsApp não abrange características de uma região específica em seu design de interação. A partir dessa premissa, foi proposta na disciplina de Interação Humano-Computador (IHC) do curso de Sistemas de Informação da Universidade Federal do Pará, cidade de Cametá-PA, a regionalização desse aplicativo. Essa disciplina considerou aspectos culturais da cidade onde o curso é ofertado e estimulou a criatividade dos alunos, a partir da aplicação das práticas de IHC na customização da interface do WhatsApp. Posteriormente, solicitou-se que os alunos avaliassem a usabilidade das interfaces propostas seguindo a norma ISO/IEC 9126. Espera-se, a partir desse relato, que outros professores possam replicar esta experiência didática no ensino de IHC.
Design de Interação no Desenvolvimento Distribuído de Software
Authors: Domingos Alves Daniel , De Souza Matos Ecivaldo
Published: January 2019

A maioria das soluções (abordagens, métodos, técnicas) de design de interação é concebida para ser utilizada em ambientes com participantes colocalizados. No entanto, é crescente o número de projetos de software que são desenvolvidos em ambientes com participantes distribuídos geograficamente. O avanço em desenvolvimento distribuído de software (DDS), aumento no número de projetos e usuários de free/libre open source software (FLOSS), problemas relacionados à interação humano-computador em DDS e desafios de design de interação em DDS motivam a condução deste estudo. Este artigo apresenta nossos esforços atuais para conceber um modelo de processo de design de interação para DDS. Como resultados parciais, identificou-se desafios, problemas e soluções de design de interação em DDS por meio de um mapeamento sistemático. Utilizando informações coletadas e analisadas por meio desse mapeamento, concebeu-se um modelo baseado em evidências para melhoria de design de interação em DDS, a ser avaliado nas próximas etapas da pesquisa.
CLUE: An Observational Checklist for Usability Evaluation of Multimodal Games for Children Who Are Blind
Authors: Darin Ticianne , Andrade Rossana , Sánchez Jaime
Published: January 2019

This paper summarizes the proposal and validation of a Checklist for Usability Evaluation of Multimodal Games for Children who are Blind (CLUE). CLUE was designed to assist researchers and practitioners in usability evaluation field studies involving people who are blind, addressing multiple aspects of gameplay and multimodality, including audio, graphics, and haptics. Overall, initial evidence indicates that the use of CLUE during user observation helps to raise a greater number of relevant usability issues than other methods such as interview and questionnaire.
Exploring an approach based on digital games for teaching programming concepts to young children
Authors: C. S. Gomes Tancicleide , Pontual da Rocha Falcão Taciana , C. A. Restelli Tedesco Patricia
Published: January 2019

Notadamente, as discussões relacionadas ao ensino de programação para crianças não são recentes e por este motivo existe uma ampla gama de recursos relacionados, como: brinquedos programáveis, brinquedos híbridos, jogos digitais, atividades com materiais analógicos, entre outros. O presente trabalho relata uma experiência baseada em jogos digitais para o ensino de conceitos de programação para crianças pequenas em fase de letramento. Nosso principal objetivo consistiu em investigar como alguns conceitos são apresentados na interface de alguns jogos e qual o impacto dos elementos de interação na compreensão das crianças sobre os conceitos apresentados. Os resultados demonstraram uma compreensão adequada de sequências de instruções e condicionais, mas indicam alguns desafios no que se refere sobretudo aos textos e elementos de interação, assim como símbolos gráficos. Outro ponto importante diz respeito ao conceito de repetição, considerado particularmente difícil de compreender pelas crianças. Sendo assim, compreendemos que embora existam diversos recursos voltados ao ensino de programação para crianças, ainda não temos boas soluções para representar e abordar alguns conceitos para crianças em fase de letramento.
Prevalence and Epidemiologic Profile of Acute Cutaneous Leishmaniasis in an Endemic Focus in Southeast Iran
Authors: Rezaee Nasrin , Shamsi Morteza , Damani Elhame , Sekandarpour Sina , Ranjbar Nasrin , Mohamdi Azad , Faizei Fariba
Published: January 2019

Background: Cutaneous leishmaniasis is a zoonotic disease, which is a public health problem in tropical and subtropical countries including Iran. Objectives: This study aimed to study the prevalence and epidemiologic profile of acute cutaneous leishmaniasis in an endemic focus in southeast Iran. Methods: In this cross-sectional study, all patients with suspected cutaneous leishmaniasis referred to health centers and health networks in Sistan and Baluchistan province since the beginning of 2013 to March 2015 were examined. Then, the collected data were prepared in the form of tables using SPSS and were analyzed by tests. Results: The percentage of leishmaniasis in men was higher than in women and there was a statistically significant difference between men and women regarding the infection rate of the disease. The results suggest a difference in the site of lesions on the body indicating confrontation with a new form of disease epidemiology. Thus, alongside the ongoing epidemiological studies, there is a need for further research in all aspects including the causes, reservoirs, hosts, prevention measures and treatments in order to control the disease.
Virtual Reality as Experiential Learning
Authors: Collette Daniel ,   Philosophy Documentation Center
Published: January 2019

While the pedagogical benefits of experiential learning are well known, classroom technology is a more contentious topic. In my experience, philosophy instructors are hesitant to embrace technology in their pedagogy. A great deal of this trepidation is justified: when technology serves only to replicate existing methods without contributing to course objectives, it unnecessarily adds extra work for the instructor and can even be a distraction from learning. However, I believe, if applied appropriately, technology can be used to positively enhance the philosophy classroom experience in ways that are not possible in traditional classroom settings – including new ways of experiential learning. To demonstrate this, I offer a case study of implementing virtual reality (VR) as a tool for experiential learning of philosophy. I show how having students “walk a plank” off a skyscraper in VR allowed me to exceed my course objectives for my Existentialism course in particularly effective ways that I could not have done without this technology.
Combined Pathology-Driven Algorithmic Testing and Integrated Reporting for Bone Marrow Examination
Authors: Pearson Lauren N. , Miller Jill M. , Lunde John H. , Bryant Ronald J. , Lewis Michael R. , Tang Mary E.
Published: January 2019

Context.—

The College of American Pathologists published guideline recommending bone marrow synoptic reporting for hematologic neoplasms.

Objective.—

To evaluate the impact of pathology-driven algorithmic testing (PDAT) with integrated reporting for bone marrow examination on test utilization, ability to render a specific World Health Organization diagnosis, and clinician satisfaction 1 year after implementation.

Design.—

We reviewed the hematopathology reports, integrated synoptic reports, and ancillary test results generated during a 12-month period. The initial diagnosis from the hematopathology report was compared with the final diagnosis on the integrated synoptic reports. Test utilization data were compared with a previous year in which ancillary testing was ordered at clinician discretion. Clinicians were anonymously surveyed to assess their satisfaction with PDAT and integrated reporting.

Results.—

Integrated reporting resulted in a World Health Organization diagnosis for 80 of 85 cases (94%) compared with 54 (64%) for the hematopathology report alone. Unnecessary testing decreased from 45% pre-PDAT (124 of 274 cases) to 0.7% PDAT (2 of 268 cases), and PDAT resulted in fewer omissions of necessary tests. Clinicians preferred PDAT and valued integrated reporting for a variety of reasons, including the ease of finding relevant prognostic information.

Conclusions.—

Pathology-driven algorithmic testing with integrated reporting improves the pathologist's ability to render a specific World Health Organization diagnosis and improves test utilization. Clinicians prefer PDAT to clinician-ordered testing. This is the first study to examine how synoptic reporting can modify hematologic diagnoses.
As tipologias de habitats de inovação: uma análise da legislação vigente do Sul do Brasil sob luz do novo marco legal de ciência, tecnologia e inovação
Authors:   Universidade Federal de Santa Catarina, Gomes Rossana Alves de Oliveira Simão , Teixeira Clarissa Stefani ,   Universidade Federal de Santa Catarina
Published: January 2019

Este artigo apresenta um comparativo entre as Leis de Inovação dos Estados da Região Sul do Brasil (Santa Catarina, Rio Grande de Sul e Paraná) e a Lei de Inovação Federal no que diz respeito à previsão expressa das tipologias de habitats de inovação. O estudo revela que os estados apoiam principalmente a implantação de parques e incubadoras. Além disso, outras tipologias ainda não são estabelecidas o que reflete a realidade brasileira em termos de número de habitats de inovação disponíveis para o apoio do empreendedorismo e da inovação.
Inovação, gestão do conhecimento e disseminação de informações: SAC da Escola do Legislativo/SC
Authors:   Assembleia Legislativa do Estado de Santa Catarina, Chaves Jussie Sedres , Correa Laura Josani Andrade ,   Assembleia Legislativa do Estado de Santa Catarina
Published: January 2019

Este artigo delimita-se em apresentar a proposta de implantação do Serviço de Atendimento ao Catarinense/SAC no intuito de inovar o gerenciamento de informações na Escola do Legislativo Catarinense. O objeto de estudo será o tratamento das informações no setor de atendimento. Para tanto, o ensaio tem como norteadores os preceitos da gestão do conhecimento, da inovação e da gestão da mudança aplicados à organização pública.
Referencial teórico em dissertações de mestrado em Administração: um levantamento de suas fontes
Authors:   Universidade Estácio de Sá, Santos Antonio Tomé Ribeiro Miranda dos , Hoshi Eduardo ,   Universidade Estácio de Sá, Troccoli Irene Raguenet ,   Universidade Estácio de Sá, Altaf Joyce Gonçalves ,   Universidade Estácio de Sá
Published: January 2019

O processo construtivo de pensamento científico depende do cumprimento de diversas etapas, consideradas clássicas para a consecução de uma investigação científica. Dentre elas, destaca-se a construção de referencial teórico que fundamente a busca de resposta a uma questão-problema. O objetivo do presente artigo é melhor entender o processo de construção de trabalhos científicos executados dentro de programa de mestrado brasileiro de elevada qualificação, por meio da verificação dos tipos de fontes que constituem os referenciais teóricos das dissertações ali defendidas. Foi identificado que a maior parte das referências foi realizada com base em livros, o que suscitou dúvida quanto aos autores das dissertações analisadas estarem de fato dispostos a se beneficiarem dos resultados de pesquisas mais contemporâneas e ou inovadoras, clássica característica dos trabalhos publicados por meio de artigos científicos.
So How Do English Language Learners Use "So"?
Authors: Lim Jessica
Published: January 2019

The present article compares the use of the discourse marker so between English-dominant speakers and English language learners through an analysis of 20 one-on-one audio-recorded sessions with 10 English-dominant speakers and 10 English language learners. While employment of the discourse marker by both speaker groups was found to be discrepant, one prominent difference was discovered in the English language learner data. Move so, one of so’s six discursive functions, was produced with a higher frequency by the English language learners. The findings of the study indicate that while the learner group demonstrated a limited range of functions, as did English language learners in prior studies, they also had an overall lower rate of frequency compared to the English-dominant speakers.
The Deliberate Non-Subtitling of L3s in Breaking Bad: A Reception Study
Authors: Krämer Mathias , Duran Eppler Eva
Published: January 2019

This paper presents the results of the first empirical reception study on the deliberate non-subtitling of L3s in the multilingual TV seriesBreaking Bad. Multilingual films and TV series are on the increase both in terms of success and penetrating wider audiences in a global market. This puts the focus on how multilingualism is conveyed to the audience and how audiences respond to it. While the translation strategies used in multilingual productions have received some attention, audiences’ reactions to them have only been investigated through an analysis of comments posted on an online movie message board. This study presents the results of a survey on the perception of and response to non-translation of L3 segments in a multilingual prestige TV series among hearing viewers. It shows that audiences are not only acutely aware of deliberate non-translation but also actively seek to identify motivations for it, which are context-sensitive and largely coincide with the filmmakers’ motivations for this practice. On the translation-theoretical side, this paper suggests that Corrius and Zabalbeascoa’s (2011) framework for the translation of L3s in dubbing would benefit from a supplement for other translation modes. On the applied side, the findings of this empirical reception study can inform agents in the international film and TV industry about audiences’ viewing preferences and potentially change AVT practices.
Womanhandling Ibsen’s A Doll’s House: Feminist Translation Strategies in a Spanish Translation from 1917
Authors: Muñiz Iris
Published: January 2019

This article analyzes a 1917 indirect translation of Ibsen’sA Doll’s House(1879) by María Lejárraga (1874-1974) as an example of early feminist translation. Relying on the existing theoretical outcomes at the intersection of gender and translation studies, it proposes a way of analyzing diverse translation strategies as a means for womanhandling the literary text, and thus making the most of the prevailing feminist interpretation of its international reception while reinforcing the budding feminist debate in Silver Age Spain and facilitating a specific understanding of the play. The importance of this case study as an example of early feminist translation is based on several factors: (a) this theatre text had a symbolic value in first wave feminism; (b) this Spanish translation was widespread due to Ibsen’s international fame and the national fame of the (overt) mediator Gregorio Martinez Sierra; (c) the feminist activism of the (covert) translator that made her select the text to spread a “thesis” she deemed necessary in Spain at that time for the developing of feminism; and (d) the numerous interventions at different levels (textual, contextual and paratextual) traceable in the translation.
Documenting Linguistic Knowledge in an Inuit Language Atlas
Authors: Murasugi Kumiko , Ittusardjuat Monica
Published: January 2019

The traditional method of orally transmitting language is weakening with the passing of fluent Elders and language erosion in contemporary Inuit society. Language documentation is a vital component of language maintenance and revitalization. In this paper we present a pilot online, multimedia cybercartographicAtlas of the Inuit Language in Canada, the goal of which is to help protect and strengthen the vitality of Inuit dialects through the documentation of their words. The main component of the atlas is a multidialectal database of written and spoken words. We discuss the role of dictionaries in language documentation, introduce the features of the atlas, explore the appeal of the atlas to different types of users (in particular, language learners), and present future directions for the atlas project.
Generating case notes from digital transcripts using text mining
Authors: Kazi Nazmul , Kahanda Indika
Published: January 2019

Current health care systems require clinicians to spend a substantial amount of time to digitally document their interactions with their patients through the use of electronic health records (EHRs), limiting the time spent on face-to-face patient care. Moreover, the use of EHRs is known to be highly inefficient due to additional time it takes for completion, which also leads to clinician burnout. In this project, we explore the feasibility of developing an automated case notes system for psychiatrists using text mining techniques that will listen to doctor-patient conversations, generate digital transcripts using speech-to-text conversion, classify information from the transcripts by identifying important keywords, and automatically generate structured case notes.

In our preliminary work, we develop a human powered doctor-patient transcript annotator and obtain a gold standard dataset through National Alliance of Mental Illness (NAMI) Montana. We model the task of classifying parts of conversations in to six broad categories such as medical and family history as a supervised classification problem and apply several popular machine learning algorithms. According to our preliminary experimental results obtained through 5-fold cross validation, Support Vector Machines are able to classify an unseen transcript with an average AUROC (area under the receiver operating characteristic curve) score of 89%. Using part-of-speech (POS) tagging, grammatical rules of English language and verb conjugation, we generate formal representation of each sample. For each class, we form a paragraph using the formal representations of its samples. Using these paragraphs, we generate a case note.
Quantitative analysis of auxin sensing in leaf primordia argues against proposed role in regulating leaf dorsoventrality
Authors: Bhatia Neha , Åhl Henrik , Jönsson Henrik , Heisler Marcus G
Published: January 2019

Dorsoventrality in leaves has been shown to depend on the pre-patterned expression of KANADI and HD-ZIPIII genes within the plant shoot apical meristem (SAM). However, it has also been proposed that asymmetric auxin levels within initiating leaves help establish leaf polarity, based in part on observations of the DII auxin sensor. By analyzing and quantifying the expression of the R2D2 auxin sensor, we find that there is no obvious asymmetry in auxin levels during Arabidopsis leaf development. We further show that the mDII control sensor also exhibits an asymmetry in expression in developing leaf primordia early on, while it becomes more symmetric at a later developmental stage as reported previously. Together with other recent findings, our results argue against the importance of auxin asymmetry in establishing leaf polarity.
The Mitotic Exit Network integrates temporal and spatial signals by distributing regulation across multiple components
Authors: Campbell Ian Winsten , Zhou Xiaoxue , Amon Angelika
Published: January 2019

GTPase signal transduction pathways control cellular decision making by integrating multiple cellular events into a single signal. The Mitotic Exit Network (MEN), a Ras-like GTPase signaling pathway, integrates spatial and temporal cues to ensure that cytokinesis only occurs after the genome has partitioned between mother and daughter cells during anaphase. Here we show that signal integration does not occur at a single step of the pathway. Rather, sequential components of the pathway are controlled in series by different signals. The spatial signal, nuclear position, regulates the MEN GTPase Tem1. The temporal signal, commencement of anaphase, is mediated by mitotic cyclin-dependent kinase (CDK) phosphorylation of the GTPase’s downstream kinases. We propose that integrating multiple signals through sequential steps in the GTPase pathway represents a generalizable principle in GTPase signaling and explains why intracellular signal transmission is a multi-step process. Serial signal integration rather than signal amplification makes multi-step signal transduction necessary.
Anillin facilitates septin assembly to prevent pathological outfoldings of central nervous system myelin
Authors: Erwig Michelle S , Patzig Julia , Steyer Anna M , Dibaj Payam , Heilmann Mareike , Heilmann Ingo , Jung Ramona B , Kusch Kathrin , Möbius Wiebke , Jahn Olaf , Nave Klaus-Armin , Werner Hauke B
Published: January 2019

Myelin serves as an axonal insulator that facilitates rapid nerve conduction along axons. By transmission electron microscopy, a healthy myelin sheath comprises compacted membrane layers spiraling around the cross-sectioned axon. Previously we identified the assembly of septin filaments in the innermost non-compacted myelin layer as one of the latest steps of myelin maturation in the central nervous system (CNS) (Patzig et al., 2016). Here we show that loss of the cytoskeletal adaptor protein anillin (ANLN) from oligodendrocytes disrupts myelin septin assembly, thereby causing the emergence of pathological myelin outfoldings. Since myelin outfoldings are a poorly understood hallmark of myelin disease and brain aging we assessed axon/myelin-units in Anln-mutant mice by focused ion beam-scanning electron microscopy (FIB-SEM); myelin outfoldings were three-dimensionally reconstructed as large sheets of multiple compact membrane layers. We suggest that anillin-dependent assembly of septin filaments scaffolds mature myelin sheaths, facilitating rapid nerve conduction in the healthy CNS.
Mesoporous Co3O4 as a New Catalyst for Allylic Oxidation of Cyclohexene
Authors: Azzi Hajer , Rekkab-Hammoumraoui I. , Chérif-Aouali L. , Choukchou-Braham A.
Published: January 2019

Mesoporous cobalt oxide was investigated for the liquid phase oxidation of cyclohexene using tertiobutylhydroperoxide (TBHP) as an oxidant. The results were compared with several series of supported cobalt catalysts to study the influence of the cobalt loading and solvents on the overall conversion and selectivity. Mesoporous cobalt was synthesized through the nanocasting route using siliceous SBA-15 mesoporous material as a hard template and cobalt nitrate as the cobalt oxide precursor. Supported cobalt oxide catalysts (Co/MxOy) were synthesized by the impregnation method using two loadings (1 and 5 wt.%) and Al2O3, TiO2, and ZrO2 as supports. Samples were characterised by means: elemental analysis, X-ray powder Diffraction (XRD), BET (surface area), UV-Vis DR Spectroscopy, and MET. The results obtained showed that the cobalt oxide retains the mesoporous structure of SBA-15, and in all Co/MxOy, crystalline Co3O4 and CoO phases are observed. The mesoporous cobalt oxide is more active than the supported cobalt catalysts in the allylic oxidation of cyclohexene, with a conversion of 78 % of cyclohexene and 43.3 % selectivity toward 2-cyclohexene-1-ol. The highest activity of mesoporous cobalt oxide could be ascribed to its largest surface area. Furthermore, Co3O4 has both Lewis and Brönsted acidic sites whereas Co/MxOy has only Lewis acidic sites, which could also explain its superior catalytic activity. Moreover, mesoporous cobalt oxide was more stable than supported cobalt catalysts. Therefore, this catalyst is promising for allylic oxidation of alkenes.
Facile Synthesis of Ag3PO4 Photocatalyst with Varied Ammonia Concentration and Its Photocatalytic Activities For Dye Removal
Authors: Febiyanto Febiyanto , Soleh Agus , Amal Muhammad Sofi Khoerul , Afif Mohammad , Sewiji Sukma , Riapanitra Anung , Sulaeman Uyi
Published: January 2019

The highly active photocatalyst of Ag3PO4 could be synthesized under ammonia solution using the facile co-precipitation method with the starting material of AgNO3 and Na2HPO4.12H2O.  The variation of ammonia concentration was designed at 0.00, 0.05, 0.15, and 0.30 M. The products were characterized using X-ray diffraction, UV-diffuse reflectance spectroscopy, and scanning electron microscopy. The photocatalytic activities were evaluated using the Rhodamine B degradation under blue light irradiation.  The effect of calcination, pH condition, and visible light source irradiation was carried out in the experiment. The highest photocatalytic activity was found in the sample prepared using the addition of ammonia solution at the concentration of 0.05 M. This photocatalytic activity was 4.13 times higher compared to the Ag3PO4 prepared without the ammonia. The effective condition of photocatalytic activity was achieved at the sample prepared without calcination, degradation at pH of 7 and under blue light irradiation.
Preparation of Metal-Free Nitrogen-Doped Carbon Material and Its Catalytic Performance
Authors: Wang Xuan , Yang Lei , Cai Ke-ying , Zhou Ying Mei , Wang Peng , Song Ming
Published: January 2019

Nitrogen-doped carbon materials (NCMs) were prepared via hydrothermal treatment together with pyrolysis under nitrogen atmosphere by using melamine as nitrogen source and sucrose as carbon source. The NCMs were characterized by X-ray diffraction (XRD), laser Raman spectroscopy and X-ray photoelectron spectroscopy (XPS). The results showed that nitrogen species were successfully doped into NCMs in the formation of pyridinic N, pyrrolic N, graphitic N, and oxidized N. With the temperature of pyrolysis increasing, the total amount of nitrogen species decreased, while the proportion of graphitic N increased. The catalytic performance was investigated by the reduction of p-nitrophenol with excessive KBH4 at 30 ℃. The reaction rate constant can reach 1.06 min-1 for NCM-800. The NCM-800 has good stability, which can be used for 8 cycles without obvious deactivation.
Kinetic Modeling of Flocculation and Coalescence in the System Emulsion of Water-Xylene-Terbutyl Oleyl Glycosides
Authors: Pawignya Harsa , Kusworo Tutuk Djoko , Pramudono Bambang
Published: January 2019

The development of a mathematical model for explaining the kinetics of flocculation and coalescence of emulsion droplets is essential to study the stability of an emulsion system of the kinetics of emulsion stability. Mathematic models was developed from the equation Van Den Tempel by modifying emulsion systems. The emulsion was made by mixing water-xylene and surfactant tert-butyl oleyl glycosides. This research studied the effect of stirrer speed on the value of flocculation rate constant (a) and coalescence rate constant (K). The model identified the emulsion development condition whether controlled by coalescence or flocculation. It was observed that under lower agitation speed (1000 rpm) the emulsion development was controlled by flocculation mechanism, while a faster agitation (2000 rpm or higher) exhibited coalescence controlled mechanism. The results confirmed that the 1st model was the most appropriate for water-xylene-TBOG emulsion system. From four models after fitting with experimental data, the most suitable model is 4th model, because it has the smallest error of 2.22 %.