bluuebunny/crossref_metadata_2025 huggingface dataset:
Hibiscus sabdariffa l.-a review on its pharmacological activity & medicinal uses
Authors: Kumari Neha , Singh Amar Pal , Singh Ajeet Pal
Published: February 2025

The shrub Hibiscus sabdariffa is a member of the Malvacea family. There are more than 200 species of hibiscus in the world. It has been noted that Hisbiscussabdariffa has numerous therapeutic benefits. The calyx is red and has five large sepals, the leaves are 7.5 to 12.5 cm long, and the fruit is a velvety capsule that is 1.25-2 cm long and green in color with five valves that each contain three to four seeds. The entire plant exhibits a wide range of pharmacological properties. The presence of phytochemicals like flavonoids, pectin, antioxidants, anthocyanins, hibiscus acid, vitamin C, protein, citric acid, and β-carotene is primarily responsible for these activities.
An Effect Of Intelligence On Academic Performance In School Going Students”: A Comparative Study Between Age And Gender
Authors: - Ayesha Anjum , - Deepika Uppalapu , - Syeda Yousra
Published: February 2025

An effect of intelligence on academic performance in school-going children is a critical area of research in educational psychology. Intelligence, often measured through standardized IQ tests, has been traditionally viewed as a significant predictor of academic success. This study examines the relationship between intelligence and academic performance, considering various factors such as socio-economic background, learning environment, and emotional well-being. Through a review of existing literature and meta-analyses, it is evident that while intelligence has a strong correlation with academic achievement, it is not the sole determinant. Other factors, including motivation, teaching quality, parental involvement, and emotional intelligence, play crucial roles in shaping a child's academic outcomes. Children who met the inclusion criteria were recruited from a private school using a Probabilistic Technique using Stratified Random Sampling with the Age range of 11 to 16 years. Academic Performance is classified into high, average and low academics using past records of final academic assessments. Intelligence Quotient was assessed using the Raven’s Standard Progressive Matrices (RSPM). In the research conducted Grade 6 students demonstrated a higher mean academic performance (M = 59, SD = 23) Compared to grade 10 students (M = 49, sd =29). The lower standard deviation in grade 6 suggests less variability in Academic performance compared to grade 10, indicating more consistency among younger students. When examining cognitive abilities using the standard progressive Matrices (SPM), Grade 10 students also showed a higher mean scores (M= 52, SD = 27) than grade 6 students (M=23, SD = 16). The substantial difference in Mean and the higher standard Deviation in grade 6 imply that cognitive abilities as measured by the SPM, improve with age but are variable in younger students.
Chrysin protects neuronal cells against carboplatin exposure-induced apoptosis and oxidative damage
Authors: Ayna Adnan , Sağ Sevda , Bayav İbrahim , Darendelioğlu Ekrem
Published: February 2025

Chemotherapy drugs such as carboplatin are commonly used to treat various cancers, including testicular, lung, and ovarian cancer. Although carboplatin primarily targets cancer cells, it can also damage healthy cells, including neurons, leading to potential adverse effects. Notably, some side effects of carboplatin therapy are associated with nerve cells and the nervous system. The aim of our study was to investigate the potential protective effects of chrysin (Chr) against carboplatin-induced toxicity in SH-SY5Y neuronal cells. In this study, the ameliorative effects of Chr on carboplatin-induced cellular toxicity were evaluated through cell viability assays, lipid peroxidation (LPO) analysis to assess antioxidant capacity, TUNEL assay, immunohistochemistry (IHC) staining, and western blotting to examine anti-apoptotic activities. The results indicated that Chr mitigates carboplatin toxicity in SH-SY5Y cells by reducing LPO levels and the expression of cytochrome c (Cyt c) and Bax, while increasing the expression of the anti-apoptotic protein Bcl-2. The study also demonstrated that carboplatin caused apoptosis by causing DNA strand breaks while Chr treatment alleviated these effects. These findings suggest that the use of antioxidants, particularly Chr, may diminish the apoptotic effects of carboplatin in SH-SY5Y cells and could provide insights into potential therapeutic strategies for mitigating cell damage caused by carboplatin.
The oocyte quality and follicular fluid lipid peroxidation and antioxidant levels in the patients undergoing in vitro fertilization treatment
Authors: Ulusoy Karatopuk Dilek
Published: February 2025

This study aimed to compare demographic, embryological, and biochemical parameters between male factor infertility and unexplained infertility groups undergoing IVF treatment. Demographic parameters such as age and BMI, along with embryological factors including the number of oocytes retrieved, MII oocytes, fertilization rate, and Grade II embryo quality, were evaluated. Biochemical markers, including MDA, GSH, GSH-Px, vitamin A, vitamin E, and ß-carotene, were also analyzed. No significant differences were observed between the two groups regarding demographic or embryological outcomes (p > 0.05), although Grade I embryo quality showed a significant difference (p = 0.047), underscoring the importance of embryo quality in IVF success. The clinical pregnancy and live birth rates were higher in the control group, but the differences were not statistically significant.

Further biochemical analysis revealed significantly higher MDA levels in the patient group, indicating increased oxidative stress (p < 0.001). Conversely, antioxidant levels, including GSH, GSH-Px, vitamin A, and vitamin E, were found to be lower in the patient group, suggesting a weakened defense against oxidative stress. These results highlight the critical role of oxidative stress and antioxidant status in IVF outcomes. Specifically, increased MDA levels and decreased antioxidant activity were linked to lower oocyte and embryo quality. Despite these findings, no significant differences were noted in pregnancy, clinical pregnancy, and birth rates between the groups.

In conclusion, this study emphasizes the importance of managing oxidative stress through antioxidant levels to potentially improve IVF success rates. Future research should further explore the biochemical parameters influencing IVF outcomes to refine treatment strategies for different infertility causes.
Minimum Degree Conditions for Hamilton $l$-Cycles in $k$-Uniform Hypergraphs
Authors: Han Jie , Sun Lin , Wang Guanghui
Published: February 2025

We show that for $ \eta>0 $ and sufficiently large $ n $, every 5-graph on $ n $ vertices with $\delta_{2}(H)\ge (91/216+\eta)\binom{n}{3}$ contains a Hamilton 2-cycle. This minimum 2-degree condition is asymptotically best possible. Moreover, we give some related results on minimum $ d $-degree conditions in $ k $-graphs that guarantee the existence of a Hamilton $ \ell $-cycle when $\ell\le d \le k-1$ and $1\le \ell < k/2$.
Some Bounds on the Threshold Dimension of Graphs
Authors: C. Francis Mathew , Majumder Atrayee , Mathew Rogers
Published: February 2025

A graph $G$ on $n$ vertices is a threshold graph if there exist real numbers $a_1,a_2, \ldots,$ $a_n$ and $b$ such that the zero-one solutions of the linear inequality $$\sum \limits_{i=1}^n a_i x_i \leq b$$ are exactly the characteristic vectors of the cliques of $G$.
The threshold dimension of a graph $G$ is the minimum number of threshold graphs whose intersection yields $G$. We give tight or nearly tight upper bounds for the threshold dimension of a graph in terms of various graph parameters including treewidth, maximum degree, degeneracy, number of vertices, and vertex cover number. We also study threshold dimension of random graphs and graphs with high girth.
Lower Bounds on Face Numbers of Polytopes with $m$ Facets
Authors: Hinman Joshua
Published: February 2025

Let $P$ be a convex $d$-polytope and $0 \leq k \leq d-1$. In 2023, this author proved the following inequalities, resolving a question of Bárány:\[\frac{f_k(P)}{f_0(P)} \geq \frac{1}{2}\biggl[\binom{\lceil \frac{d}{2} \rceil}{k} + \binom{\lfloor \frac{d}{2} \rfloor}{k}\biggr],\qquad\frac{f_k(P)}{f_{d-1}(P)} \geq \frac{1}{2}\biggl[\binom{\lceil \frac{d}{2} \rceil}{d-k-1} + \binom{\lfloor \frac{d}{2} \rfloor}{d-k-1}\biggr].\]
We show that for any fixed $d$ and $k$, these are the tightest possible linear bounds on $f_k(P)$ in terms of $f_0(P)$ or $f_{d-1}(P)$. We then give a stronger bound on $f_k(P)$ in terms of the Grassmann angle sum $\gamma_k^2(P)$. Finally, we prove an identity relating the face numbers of a polytope with the behavior of its facets under a fixed orthogonal projection of codimension two.
Integrating Social Prescribing into Primary Care: Policy Implications and Educational Needs in Medan, Indonesia
Authors: Ni Made Nova Indriyani  , Lisye Tiur Simanjuntak  , Badrool Nizham  , Ramakhrisnand Ramakhrisnand
Published: February 2025

Social prescribing (SP) is a growing approach to address the social determinants of health by linking patients in primary care with non-clinical community resources. Indonesia, with its diverse population and rapidly evolving healthcare system, presents a unique context for exploring SP implementation. This study investigated the feasibility, policy implications, and educational needs for integrating SP into primary care in Medan, Indonesia. A mixed-methods approach was employed. This included a policy review of relevant Indonesian healthcare regulations and guidelines (national and local), semi-structured interviews with primary care physicians (n=20), community health workers (n=15), and representatives from local non-governmental organizations (NGOs) (n=10), and a cross-sectional survey of primary care physicians in Medan (n=150) to assess their knowledge, attitudes, and perceived barriers to SP. Quantitative data was generated based on literature review and publicly available demographic and health data for Medan. Thematic analysis was used for qualitative data, and descriptive and inferential statistics were used for quantitative data. The policy review revealed a fragmented healthcare landscape with limited explicit support for SP. Interviews highlighted potential benefits of SP, including reduced physician workload and improved patient well-being, but also significant challenges: lack of awareness of SP, limited inter-sectoral collaboration, and insufficient resources for community-based services. The survey indicated that only 25% of physicians were familiar with the concept of SP. Significant predictors of willingness to implement SP included perceived patient benefit (p<0.001) and availability of referral pathways (p<0.01). Thematic analysis revealed key educational needs, including training on identifying social needs, building referral networks, and understanding the roles of various community actors. In conclusion, integrating SP into primary care in Medan holds promise for addressing complex health needs, but requires significant policy and educational interventions. Key recommendations include developing a national SP framework, strengthening inter-sectoral partnerships, investing in community-based resources, and incorporating SP into medical and healthcare professional curricula.
Új környezeti célok, fejlődő közbeszerzési megoldások
Authors: Poór Péter
Published: February 2025

A környezet védelme napjainkban egyre inkább előtérbe kerül és lassan megkerülhetetlenné válik. Ezt támasztják alá az ismertetésre kerülő környezetvédelmi nemzetközi megállapodások és az önkéntes vállalások. Az elérni kívánt célok teljesítése érdekében a közbeszerzések során elengedhetetlen a zöld szempontok alkalmazása. Bemutatásra kerül, hogy az ajánlatkérők számára a jelenleg hatályos jogszabályok mentén, milyen megoldási lehetőségek állnak rendelkezésre a zöld szempontok beépítésére közbeszerzési eljárások során. Végezetül bemutatásra kerül a zöld közbeszerzések arányának növekedésének gátja és a lehetséges megoldási javaslatok.
Az üzleti titok ajánlatkérői és ajánlattevői szemszögből
Authors: Nyerges Éva
Published: February 2025

Az üzleti titok kérdésköre mind az ajánlattevők, mind az ajánlatkérők számára fontos és érdekes, és annak ellenére, hogy nem új a szabályozás, továbbra is vet fel kérdéseket mindkét fél részéről, amit az igen gazdag döntőbizottsági gyakorlat is alátámaszt. Az ajánlattevőnek lehetősége van üzleti titokká nyilvánítani bizonyos iratokat, az azokban lévő információkra tekintettel, azonban ezt csak megfelelő indokolással együtt teheti meg. Az ajánlatkérő feladata annak ellenőrzése, hogy az üzleti titokká nyilvánított dokumentum valóban csak olyan adatokat, információkat tartalmaz-e, amelyek a közbeszerzésekről szóló 2015. évi CXLIII. törvény (továbbiakban: Kbt.) 44. §-a alapján üzleti titokká nyilváníthatók, és az ajánlattevői indoklás megfelelőségét is ellenőriznie kell az ajánlatkérőnek. A feleknek talán az indokolás jelenti a legnehezebb feladatot, hiszen az ajánlattevőnek úgy kell megindokolnia az üzleti titkát, hogy azt nem fedi fel, de az általánosság szintjén túlmutatónak kell lennie, az ajánlatkérőnek pedig abban kell döntést hoznia, hogy megfelelő-e az indokolás. Jelen szakcikk mindkét fél irányából próbálja bemutatni az üzleti titokkal kapcsolatos jogszabályi elvárásokat és teendőket, illetve a döntőbizottsági gyakorlatot is.
Some Influential Diagnostics in New Two-Parameter Estimator in the presence of multicollinearity and extreme values: Simulations and Applications
Authors: Adejumo Aiwo Joel , Ayinde Kayode , Adewuyi Emmanuel Taiwo , Adejumo Christiana Toyin
Published: February 2025

Identifying influential points in linear regression is vital for ensuring the validity of inferential conclusions. Traditional diagnostic measures, such as DFFITs (DFT), Cook’s D (CKD), COVRATIO (CVR), Hadi’s measure (HAD), Pena’s statistic (PEN), and Atkinson statistic (ATK), are typically based on the Ordinary Least Squares (OLS) estimator, which assumes no violation of the basic linear regression assumptions. This study develops new diagnostic measures for these statistics using the New Two-Parameter (NTP) estimator to address multicollinearity. The study evaluated the performance of these measures through simulation studies with 1,000 replications under varying levels of multicollinearity, error variances, outlier percentages and magnitudes, and sample sizes. Results revealed that the newly proposed CVR measure with the NTP estimator achieved 100% detection of influential points and recorded the highest detection counts, outperforming all other measures. While traditional measures like CKD, PEN, and ATK based on OLS were effective only for small sample sizes in the absence of multicollinearity, their performance declined when multicollinearity was present. Conversely, CVRNTP consistently demonstrated superior performance when multicollinearity was mitigated. These findings suggest that the proposed CVRNTP is a robust tool for identifying influential points in datasets affected by multicollinearity. Real-life data applications further validated their performances.
The Beginning Of The Process Of Rehabilitation Of Victims Of Political Repression In The Khmelnytskyi Region In The 1950s
Authors:   Leonid Yuzkov Khmelnytskyi University of Management and Law, MISINKEVYCH Leonid
Published: February 2025

The features of the amnesty of March 27, 1953, which the party leadership perceived as the beginning of mass rehabilitation, are considered, however, it did not contribute to releasing victims of political repression. Measures for employment and social adaptation of amnestied citizens are analyzed. Attention was paid to the elimination of extrajudicial bodies, changing the structure and subordination of repressive institutions to party committees. The creation of special commissions to review the cases of those convicted for political reasons, their composition, powers, and the results of the activities of the Central and local commissions were investigated. Deficiencies in the work of regional commissions were identified, in particular, their formal approach to reviewing cases, inertia in correcting judicial errors, and the dominance of the guilt factor. The main reason for the shortcomings was the involvement in the rehabilitation process of lawyers who had previously actively participated in repressions, using illegal investigative methods and ignoring the rights of convicts. It was found that the review of criminal cases mostly ended with the release of prisoners, taking into account the term of sentence served, but without the removal of criminal records, which makes it impossible to assess these actions as full rehabilitation. The work of the commissions of the Presidium of the Supreme Soviet of the USSR and local commissions formed after the 20th Congress of the CPSU is analyzed in the context of reviewing cases of political, official, and economic crimes. Their efforts to employ illegally convicted persons are highlighted separately. Law enforcement officers' subjective and dogmatic approaches in restoring the rights of the repressed are emphasized. It has been established that the specified period of the country’s socio-political life was characterized by the active preparation of regulatory and legal documents based on party decisions that determined the legal principles of rehabilitation. The study analyzed the circumstances under which the republican and regional commissions refused to rehabilitate those repressed and extrajudicially imprisoned. The process of reviewing archival and investigative cases, as well as the activities of the Prosecutor’s Office of the Ukrainian SSR, in particular the involvement of employees of city and district prosecutor’s offices in rehabilitation activities, was considered.
Analysis of the composition of black cumin for the purpose of developing a component-concentrate based on milk whey and synthesised nigelone for use in the cosmetic industry
Authors:   North-Caucasus Federal University Yemelyanov, Chikatueva M. A. , Yemelyanov S. A. ,   North-Caucasus Federal University
Published: February 2025

Consumer preference studies conducted in the cosmetics industry consistently show an advantage among components of natural origin. Important criteria in the development of cosmetics are the absence of toxic, allergic reactions, the ability of intracellular delivery of active substances and the provision of prolonged biological action. It seems relevant to our creative team to develop a concentrate component based on a unique composition of whey and an effective actioxidant - nigelog from black cumin, which will meet the modern criteria of innovative cosmetics industry products.
Prospects for the implementation of artificial intelligence in renewable energy management
Authors:   North-Caucasus Federal University, Pyatigorsk Institute (branch), Rostova A. T. , Sokolov A. A. ,   North-Caucasus Federal University, Pyatigorsk Institute (branch), Masyutina G. V. ,   North-Caucasus Federal University, Pyatigorsk Institute (branch)
Published: February 2025

The article is an attempt at research in the field of the use of artificial intelligence (AI). The efficiency of using artificial intelligence (AI) technologies to control the load at the plant, energy generation from renewable energy sources, and the use of AI in these processes is analyzed. The research of the current state and prospects of AI development in various industries and directions, the complexity in the multidimensional use of Artificial Intelligence at power plants in the areas of "green energy" are analyzed.
The integration process in central Asia as a factor in ensuring the security of the region
Authors:   Ural Federal University, Kerimov A. A. , Bobojonov G. M. ,   Ural Federal University
Published: February 2025

This article examines the process of integration in Central Asia, as well as the relationship of the countries of this region with world powers. Since gaining independence, Central Asia has faced many interstate problems that have actualized issues of regional integration. The article analyzes the stages of integration, as well as the factors contributing to disintegration processes. The sides also discuss aspects of cooperation between the countries of the region in the field of water diplomacy and cross-border relations in order to strengthen borders with Afghanistan.
Evaluative representations of the student audience in the context of current processes in Donbas: comparison of studies
Authors:   Southern Scientific Centre of the Russian Academy of Sciences, L. B. Vnukova L. B.
Published: February 2025

The article examines the features and trends in the views of the surveyed student audience in comparison with the general array of respondents regarding current socio-political processes in Russia. The results and conclusions are correlated and verified with All-Russian representative surveys and academic research on intergenerational differences in assessments and perceptions on similar topics. The article examines data on attitudes towards historical events, current socio-political processes, the conduct of a special military operation and partial mobilization, issues of self-identification, etc. The anonymous survey was conducted by means of "Anketolog" in May - June 2023 in different regions of Russia. Due to the difficulty of reaching respondents in new territories, the survey was conducted using the "snowball" method. The main research method is a comparative analysis of the data obtained using sociological information and relevant academic research. The analysis revealed that the views of the student audience (who showed interest to the survey) are characterized by a number of features. The responding group is politicized, adheres to individualistic positions. It is not ideologically homogeneous and has alternative judgments about historical events. First of all, we can identify those who positively assess modern processes and those who take critical positions. Accordingly, a dichotomy of opinions appears: some share the belief that Russia is a strong power with an independent path of development, while others see themselves as part of a European (global) civilization. The differences in views between the older generations and the youth are evidenced by All-Russian representative surveys and numerous scientific studies. In our opinion, the situation of opinion breakdown is exacerbated by the great immersion of modern youth in the digital environment, in which the algorithms of Internet media and social networks influence the nature and presentation of information.
Oscillating infrared drying of apple peels
Authors:   Institute of Mechanics and Power Engineering named after V.P. Goryachkin, Russian State Agrarian University – Timiryazev Agricultural Academy, Rudobashta S. P. , Podyablonskaya D. O. ,   Institute of Mechanics and Power Engineering named after V. P. Goryachkin, Russian State Agrarian University – Moscow Agricultural Academy named after K.A. Timiryazev, Kazub V. T. ,   Pyatigorsk Medical and Pharmaceutical University (branch) of VolGMU in Pyatigorsk, Lago L. A. ,   Crimean Federal University named after V.I. Vernadsky
Published: February 2025

The oscillating infrared drying of Gala apple peel has been experimentally studied. The product has valuable nutritional properties and is in demand in the food industry. On the developed laboratory setup for studying the oscillating infrared drying process and maintaining the temperature of the dried material at a given temperature level, drying curves were obtained at three average material temperatures: t = 37 °C; 47 °C and 57 °C. OSRAM Siccatherm lamps were used as infrared radiation sources. The drying curves contained the first and second periods, the critical moisture content was equal to (kg moisture) / (kg dry material). As a result of the drying curves analysis, it was proposed to calculate the duration of the first period based on the drying rate, determined through the mass transfer coefficient, and the duration of the second period by generalizing the drying curves using the method of V.V. Krasnikov. For the studied material, the value of the relative drying coefficient (χ = 0.0624) was found, which allows implementing this method for the studied material. Data on the preservation of vitamin C in apple peel dried at different temperatures were obtained, which allows choosing the required temperature regime.
The importance of mathematical logic schemes in artificial intelligence
Authors:   Associate Professor of the Department of “Information Technologies” of Andijan State Technical Institute, Uzbekistan, Makhmudovich Zulfikharov Ilkhom , Husanboy Olimjonov ,   Andijan State Technical Institute, 3rd year student, “Artificial Intelligence” program, Uzbekistan
Published: February 2025

This аrticle аnаlyzes the impоrtаnce оf lоgic circuits in аrtificiаl intelligence systems аnd their аpplicаtiоn in vаriоus fields. Infоrmаtiоn is prоvided оn the principles оf оperаtiоn, structure аnd implementаtiоn stаges оf lоgic circuits in аrtificiаl intelligence. Exаmples оf increаsing the efficiency оf lоgic circuits in аrtificiаl intelligence systems аnd their аpplicаtiоn in reаl life аre given.
Use of AL-KARAJI method in calculating sum
Authors:   Tashkent State Technical University named after Islam Karimov, Uzbekistan, Kaxxorov Azizbek , Shernayev Akmal ,   Tashkent State Technical University named after Islam Karimov, Uzbekistan
Published: February 2025

This article provides several ways to find the sum of some number series. Al-Karaji's contribution to the science of mathematics lies in the method that he used to calculate the sums, and finding of the sum of a series of cubes of natural numbers is proved in this way. To explain al-Karaji's method more widely, other sums were calculated in the same way, and a general result was obtained.
Developing students' interest in knowledge through extracurricular educational activities
Authors:   Associate professor, Bukhara State Pedagogical Institute, Head of the Department of Preschool and Primary Education Pedagogy, Uzbekistan, Qosimovna Hasanova Gulnoz
Published: February 2025

The development of students’ interest in knowledge is a crucial aspect of modern education. While traditional classroom instruction plays a significant role in shaping students’ cognitive abilities, extracurricular activities offer additional opportunities to foster curiosity and a passion for learning. This study explores how extracurricular educational activities enhance students’ interest in acquiring knowledge. By analyzing various extracurricular programs, their implementation, and their effects on students' academic engagement, the study provides insights into effective strategies for educators. The results suggest that extracurricular activities not only supplement academic learning but also cultivate a deeper appreciation for knowledge, thus contributing to students’ overall intellectual and personal development.
The importance of pedagogical psychology in higher education
Authors:   Deputy Dean for Youth Affairs, Spiritual and Enlightenment Affairs, Mamun University, Doctor of Philosophy in Philosophy (PhD), Uzbekistan, Akhmedjanovich Saidnazarov Ulug‘bek
Published: February 2025

The article examines the importance of pedagogical psychology in the process of higher education and its impact on student development. Pedagogical psychology plays an important role in making educational and upbringing processes more effective and person-oriented. The article examines the contribution of pedagogical psychology to students' learning ability, motivation, personal and social development, as well as the psychological preparation of teachers and their effectiveness in their professional activities. The results of the study show that the level of knowledge and personal potential of students can be increased by applying pedagogical psychology to higher education.
Training using virtual and augmented reality
Authors:   Assistant of the Department of "Informatics and Computer Graphics" of Tashkent State Transport University, Uzbekistan, Vladimirovna Kodirova Yelena
Published: February 2025

In the context of the rapid development of technologies and the digitalization of society, education faces new challenges. Traditional teaching methods often struggle to engage students and explain complex concepts. Virtual Reality (VR) and Augmented Reality (AR) represent innovative approaches that can significantly enhance the educational process. These technologies allow for the creation of interactive and engaging learning materials that promote a deeper understanding of the subject. In particular, in the field of informatics, where abstract concepts can be difficult to grasp, VR and AR open new horizons for learning.
The therapeutic benefits of berberine and its effectiveness compared to metformin
Authors:   British-Trained Anthropologist. Swiss and German - trained Naturopath and Nutritionist, Chubin Karim
Published: February 2025

Berberine is a plant extract that exhibits an impressive array of therapeutic properties, including accelerated weight loss, improved insulin sensitivity, and protection from numerous chronic, degenerative diseases. Berberine exerts its effects in several ways, including by activating AMP- activated protein kinase (AMPK), an enzyme that governs metabolism and maintains whole-body energy homeostasis. Since AMPK influences the ageing process, long-term berberine consumption may extend lifespan by decelerating one’s rate of ageing. Besides its impact on AMPK, berberine also profoundly alters the gut microbiome, specifically in ways that reduce metabolic endotoxemia, a condition that promotes obesity and other metabolic disorders.

Berberine’s physiological effects are similar to those of metformin, but in comparative studies, berberine either matches or outperforms metformin. Considering metformin’s minor side effects, berberine’s absence of side effects, and berberine’s therapeutic potential against neurological degenerative diseases and a host of other chronic conditions, berberine is quickly gaining recognition for being one of the most powerful and most effective nutritional agents for weight loss, disease prevention, anti-ageing, and overall wellness.
Comparative Analysis Of Conventional Banks Financial Performance Before And During The Covid-19 Pandemic
Authors: Sari Ervina Indri , Lestary Fellya Destriliawaty Indah , Nurjanah Yayuk
Published: February 2025

The Covid-19 pandemic has had a significant impact on the banking sector, especially conventional banks. This study analyzes the comparison of the financial performance of conventional banks before and during the COVID-19 pandemic in the 2018–2021 period. The type of research used in this study is comparative research with a quantitative research method approach, with the Purposive Sampling sampling technique obtained a sample of 40 conventional banks in the 2018-2021 period. This study uses the CAMEL method to assess the financial health of banks based on the Capital Adequacy Ratio (CAR)), Asset Aspect (Productive Asset Quality (KAP)), Management Aspect (Net Interest Margin (NIM)), Earning Aspect (Return On Assets (ROA) & Operating Costs to Operating Income (BOPO)), and Liquidity Aspect (Loan to Deposit Ratio (LDR)). Data was obtained from financial statements that had been audited and analyzed using the paired t-test and the Wilcoxon signed-rank test.
The results showed that there were significant differences in CAR, NIM, ROA, BOPO, and LDR before and during the pandemic, indicating changes in banks' risk management strategies, profitability, and efficiency in the face of crises. However, asset quality (KAP) did not show a significant difference, indicating that banks are still able to maintain stability in credit returns despite economic disruptions. This study has limitations on the scope of the sample which only includes banks listed on the stock exchange and does not consider external factors outside the financial sector. The results of this study provide insight into the resilience of conventional banks in facing economic crises and become a reference for policymakers and financial institutions in strengthening banking stability in the future.
 
Keywords: Financial Performance, CAMEL Method, Covid-19
Breast cancer surveillance: practices identified by managers in Primary Care
Authors: Loyola Edilaine Assunção Caetano de , Goldman Rosely Erlach , Figueiredo Elisabeth Niglio , Tintori Janaína Aparecida , Almeida Ana Maria de , Panobianco Marislei Sanches
Published: February 2025

Abstract Objective To analyze the breast cancer management practices identified by Primary Health Care managers. Methods This is a descriptive, cross-sectional study, carried out with 24 Health Units managers in Primary Care, of different configurations (traditional, Family Health Strategy and Basic Health Units with Family Health teams) and contemplating small, medium and large units, located in a city in the countryside of São Paulo. An instrument was used to identify screening and detection actions for breast cancer, with 32 questions and sub-items, according to the actions determined by the breast cancer management program in Brazil. The analysis was based on Donabedian Model’s structure and process attributes. Results With regard to breast cancer management actions, all managers, 24 (100%), stated that they established priority in referring women with altered mammography and Clinical Breast Examination, and requesting mammography for women in the high-risk group. As for obstacles in the execution of these actions, most, 13 (54.2%), managers pointed out difficulties faced by the services, with a predominance of lack of health professionals and excessive demand. Conclusion The Primary Care Health Units have carried out actions to manage breast cancer, but there are behaviors that do not comply with the Ministry of Health’s proposals. There is a need for greater implementation of educational actions, as the focus is curative. Also, greater investments are needed to increase preventive measures and enhance access to screening tests.
Industria 4.0 y sostenibilidad: evaluación del compromiso organizacional con la agenda 2030 desde un enfoque bibliométrico
Authors: Liarte-Vejrup Nicolás , Bermúdez González Guillermo J. , Álvarez Novell Alejandro
Published: February 2025

La sostenibilidad ofrece múltiples oportunidades a las empresas que deseen innovar, y desarrollar estrategias de triple impacto en la vinculación con sus stakeholders, en particular las llamadas industria 4.0, una nueva fase de la revolución industrial basada en la interconectividad, el aprendizaje automatizado y los datos en tiempo real. Este paper es un estudio bibliométrico que tiene por finalidad poner en perspectiva el aporte de las industrias 4.0 y su contribución a la agenda 2030. 
 
AbstractSustainability offers multiple opportunities for companies wishing to innovate and develop triple impact stakeholder engagement strategies, particularly the so called Industry 4.0, a new phase of the industrial revolution based on interconnectivity, machine learning and real-time data. This paper is a bibliometric study that aims to put into perspective the contribution of Industry 4.0 and its contribution to the 2030 agenda.
Diseño y validación de contenido del índice estratégico de marketing digital (IEMD)
Authors: Guzmán Pacheco Juan Felipe
Published: February 2025

En la era digital, el marketing se ha transformado en un ecosistema dinámico y complejo, donde las empresas enfrentan el desafío de medir y optimizar sus estrategias digitales. Este estudio tiene como objetivo desarrollar y validar un índice integral para evaluar las estrategias de marketing digital en empresas colombianas. La metodología incluyó el diseño de un instrumento basado en categorías teóricas fundamentales y validado mediante el Índice de Validez de Contenido (IVC) y el Índice Kappa. Los resultados muestran un IVC promedio de 1.0, reflejando alta validez de contenido, mientras que el Kappa promedio de 0.571 indica un acuerdo moderado entre los jueces. Este instrumento permite a las empresas diagnosticar el estado actual de sus estrategias digitales, identificar áreas de mejora y optimizar su desempeño en entornos competitivos.
THE ROLE OF IPS LEARNING IN SHAPING STUDENTS' CRITICAL UNDERSTANDING OF THE COMMODIFICATION OF BELIS CULTURE IN MANGGARAI
Authors: Tanggur Femberianus Sunario , Tri Atmaja Hamdan , Wisnuwardana I G W , Saddam Saddam , Nuryanti Nuryanti
Published: February 2025

ABSTRACT
This research aims to analyze the role of Social Studies learning in shaping students' critical understanding of the phenomenon of commodification of Belis culture in Manggarai. The method used was a qualitative approach with a case study design, involving 132 students at SMP Negeri 9 Borong, East Manggarai, as well as teachers and the surrounding community. Data were collected through in-depth interviews, observation, and documentation, and analyzed using thematic analysis. The main findings of this study show that social studies learning plays an important role in raising students' social awareness of the phenomenon of commodification of Belis culture. Although most students understand the culture of Belis, they do not fully understand the social and economic impacts of changing the form of Belis, from livestock to money. Social studies learning is able to stimulate students' critical thinking, but there are still gaps in their understanding of the wider implications of commodification on the cultural values and social structure of Manggarai society. In conclusion, social studies learning needs to be adapted to the local context to be more relevant to social and cultural conditions, as well as to encourage students to think more critically and actively in preserving Belis culture in the midst of changing times.
PSYCHO-AFFECTIVE RESPONSES IN MIDDLE-AGED RECREATIONAL RUNNERS TO SELF-ADJUSTING COUNTERCLOCKWISE STIMULI.
Authors: Albernaz Thiago , Inácio Pedro Augusto , Rocha Fernanda Pereira da Silva , Nascimento David dos Santos , Silva Adriano Coelho , Barsanulfo Junior Silvio Roberto , Santos Danielly Carrijo Pereira dos , Caixeta Davi Costa , Cardozo Rafael dos Santos , Rodrigues Anne Caroline de Almeida , Carvalho Alessandro Oliveira de , Sales Marcelo Magalhães , Machado Sérgio , Filho Alberto Souza de Sá
Published: February 2025

Staying in a training program allows its practitioners to improve in daily activities, generating less energy expenditure to perform them, and in sports practice, executing movements with quality leads to achievements. Nowadays, where the population is increasingly busy and more exposed to technological conveniences, there is a great need for adjustments in training methods, whether for strength, aerobic, power, or flexibility [1].
Adherence to training involves an integrated balance between the mind and body, where the understanding of the physiological impact provided, and how this impact is individually perceived during and after physical exercise, define subsequent human behavior and its potential relationship with adherence to training [2]. The individual understanding of affective responses can be characterized as positive, that is, the perception of stimuli provided well-being and tranquility, and generally reduced tension, or negative, where the brain perceives the offered stimulus as a stressor mechanism, increasing the state of anxiety and tension [3].
We currently know that, primarily, high-intensity interval exercises are being prioritized for training prescriptions within major training centers and gyms [4, 5]
However, while such a mode of exercise can exert potential benefits and rapid physiological changes, when used indiscriminately, it can provide negative affective responses and a possible strain in the practitioners' relationship with physical exercise. A possible solution to this impasse seems to be the self-selection of work speeds by the participants themselves. In this case, no matter how much they are asked and encouraged to take on a high workload, the mere perception of non-imposition and self-regulation can modulate differentiated affective responses, inducing positive interpretations. Despite the empirical nature of this theory, such phenomena still need to be more thoroughly investigated.
Improved Spectral Amplitude Modulation Based on Sparse Feature Adaptive Convolution for Variable Speed Fault Diagnosis of Bearing
Authors: Lin Jiawei , Han Changkun , Lu Wei , Song Liuyang , Chen Peng , Wang Huaqing
Published: February 2025

Difficulty in extracting nonlinear sparse impulse features due to variable speed conditions and redundant noise interference leads to challenges in diagnosing variable speed faults. Therefore, an improved spectral amplitude modulation based on sparse feature adaptive convolution (ISAM-SFAC) is proposed to enhance the fault features under variable speed condition. First, an optimal bi-damped wavelet construction method is proposed to learn signal impulse features, which selects the optimal bi-damped wavelet parameters with correlation criterion and particle swarm optimization (PSO). Second, a convolutional basis pursuit denoising model based on optimal bi-damped wavelet is proposed for resolving sparse impulses. A model regularization parameter selection method based on weighted fault characteristic amplitude ratio (WFCAR) assistance is proposed. Then, an improved spectral amplitude modulation method based on kurtosis threshold is proposed to further enhance the fault information of sparse signal. Finally, the type of variable speed faults is determined by order spectrum analysis. Various experimental results, such as spectral amplitude modulation and Morlet wavelet matching, verify the effectiveness and advantages of the ISAM-SFAC method.
 
Conflict of Interest Statement
The authors declare no conflicts of interest.
The Effect of Audit Committee, Institutional Ownership, Independent Commissioners, and Sales Growth on Tax Avoidance (Empirical Study of Mining Sector Companies Listed on the Indonesia Stock Exchange in 2017-2022)
Authors: MARIANTO Marianto , SUHARMADI Suharmadi
Published: February 2025

This study aims to examine and analyze the effect of the audit committee, institutional ownership, independent commissioners, and sales growth on tax avoidance. The object of this research is mining sector companies listed on the Indonesia Stock Exchange (IDX) from 2017 to 2022. The sample in this study was obtained using a non-probability sampling technique, specifically purposive sampling. The study utilized a sample of 17 companies over a 6-year period. The data analysis method used was multiple linear regression analysis with the assistance of IBM SPSS Statistics version 27. The results of this study indicate that the audit committee and institutional ownership have a negative and significant effect on tax avoidance, while independent commissioners and sales growth do not have a significant effect on tax avoidance.
Party-Id and Money Politics in The Dynamics of The 2024 Presidential and Vice Presidential Elections in Kupang City
Authors: HUMAU Frans Bertho Ricky , JACOB Ananias Riyoan Philip , TRIADMAJA Stefanus , NDODA Philips Yuniory Nyaleson
Published: February 2025

The weakening of party identification has become a unique phenomenon from year to year, in the context of elections this weakening has caused several negative effects, one of which is the practice of money politics that is increasingly massive in society. In other words, strong party identification will reduce the practice of money politics. This hypothesis will be tried to be proven by this research by looking at the influence of party identification on money politics that occurs in the community, especially in the Presidential and Vice Presidential Elections in Kupang City in 2024. The method used in this study is a quantitative method using a survey technique of 440 respondents spread across six sub-districts in Kupang City. The conclusion obtained in this study is that party identification does not have a positive impact on public acceptance of money politics. The weak identification of parties in Kupang City is caused by the structure and institutionalization of political parties that are not running optimally. On the other hand, the people of Kupang City tend to prioritize a person's character rather than party identification. The results of the 2024 election again prove that the identification of community parties in Kupang City is still quite low.
Can thiệp sức khỏe tâm thần cho học sinh 4 trường trung học phổ thông tại Hà Nội: Kết quả đánh giá quá trình
Authors:   Hanoi University of Public Health, Nga Nguyen Thi , Tran Duc Thach ,   Monash University, Australia, Nguyen Thanh Huong ,   Hanoi University of Public Health
Published: February 2025

Objective: To evaluate the process of implementing a mental health intervention among 10th grade students at 4 high schools in Hanoi in 2020. Methods: A cross-sectional study combined qualitative and quantitative methods was conducted. Qualitative research involved 4 in-depth interviews and 5 focus group interviews with students, researchers, teachers and school representatives. For the quantitative research, a total of 525 students were recruited using multi-stage sampling. Data analysis included a content analysis and descriptive analysis by Stata 16.0. Results: There was 6 out of 7 intervention activities was implemented as planned. The program was adjusted and supplemented appropriate activities due to the impact of the COVID-19 pandemic and feedback from students and stakeholders to ensure program progress. The participation rate in the 4 intervention activities for students was very high (ranging from 87.6% to 98.5%) with higher rates among female students and students in suburban areas. Approximately two-thirds to over three-quarters of students expressed satisfyaction with intervention activities. Conclusion: Most of the intervention activities were implemented on schedule had a fairly high coverage rate and students were satisfied. Further interventions should consider establishing a monitoring and support group at all levels to ensure progress, suitability and satisfaction of students.
Keywords: Process evaluation, mental health intervention, adolescent, high school.
Painting on sculptures in fifteenth-century Florence: case studies
Authors: D’Elia Una Roman
Published: February 2025

This article focuses on the painted and gilded surfaces of sculptures in fifteenth-century Florence, offering a few case studies to suggest the variety of ways in which painters brought three-dimensional works to life. Paint adds shifting colours that mimic the warmth of flesh, but also shadows and highlights that change the perception of form. The paint can be extremely fine – infinitely delicately delineated eyelashes – or rough, with seemingly splashed-on blood that is in fact carefully executed. The painter Neri di Bicci uses the terms ‘incarnation’ and ‘ornament’ to describe his painting and gilding on three-dimensional objects. The examples discussed here likewise demonstrate how the painted surface counterfeits both splendidly rich fabrics and pearly feminine and ruddy masculine skin, creating the illusion of flourishing or dying bodies. By examining the surfaces of a few sculptures and comparing these to each other and to contemporary panel paintings, this article suggests preliminary observations and directions for future research. The purpose is to offer a prologue to what would be far beyond the scope of this brief essay, namely the history of Renaissance painting in three dimensions.