bluuebunny/crossref_metadata_2025 huggingface dataset:
دور الجامعات السعودية في تفعيل لجان الاستثمار في ضوء اللائحة المالية الجديدة للجامعات السعودية
Authors: بن دخيل الطيار مهند بن سعود , بن حمد الحواس حمد بن خالد
Published: June 2024

هدفت الدراسة إلى التعرف على دور الجامعات السعودية في تفعيل لجان الاستثمار في ضوء اللائحة المالية الجديدة للجامعات السعودية، وذلك من خلال استعراض نظام الجامعات الجديد وفقا لمتطلبات رؤية المملكة 2030، وتقديم المقترحات لتفعيل الاستثمار الجامعي، واستخدمت الدراسة المنهج الوصفي التحليلي باستخدام المقابلة المقننة المفتوحة لاستعراض وتحليل أراء عدد (10) من الخبراء والمختصين في هذه اللائحة، وتوضيح أبرز التعديلات التي أجريت عليها، وأيضاً تحديد المتطلبات ودور الجامعات لتفعيل لجان الاستثمار بشكل أمثل في ضوء تلك اللائحة، وأسفرت نتائج الدراسة عن أن الجامعات السعودية لها دور رئيسي في تفعيل الاستثمار من خلال وضع التشريعات والأنظمة القانونية للقيام بعملية الاستثمار، وتدريب منسوبها، وتوفير البنية التحتية والفوقية، وتسخير منشأتها لتحقيق أهداف الاستثمار. كما تتعدد أدوار لجان الاستثمار في الجامعات من حيث تقديم الخطط الاستثمارية للتعليم، وتحديث قاعدة البيانات للأصول الاستثمارية، والتعاون مع القطاع الخاص والعمل على رفع كفاءة الجامعة في الاستثمارات المتنوعة. وقد أوصت الدراسة بضرورة تدريب منسوب الجامعات السعودية والاستفادة من التجارب العالمية والعمل على تبسيط الإجراءات والأنظمة الإدارية في مجال تمويل الجامعات.
Clustering of Communicable Diseases in Indonesia and the Factors that Affect Them: 2018 Basic Health Research Data Statistical Review
Authors:   Department of Statistics, IPB University, Bogor, Aidi Muhammad Nur , Aditra Taufiqur Rakhim ,   Department of plastic and construction surgery, Airlangga University, Surabaya, Ernawati Fitrah ,   Research Center for Public Health and Nutrition, National Research and Innovation Agency, Indonesia, Nurjanah Nunung ,   Research Center for Public Health and Nutrition, National Research and Innovation Agency, Indonesia, Efriwati Efriwati ,   Research Center for Public Health and Nutrition, National Research and Innovation Agency, Indonesia, Julianti Elisa Diana ,   Research Center for Public Health and Nutrition, National Research and Innovation Agency, Indonesia, Sundari Dian ,   Research Center for Public Health and Nutrition, National Research and Innovation Agency, Indonesia, Retiaty Fifi ,   Research Center for Public Health and Nutrition, National Research and Innovation Agency, Indonesia, Rachmawati Rika ,   Research Center for Public Health and Nutrition, National Research and Innovation Agency, Indonesia, Dewi Rita Marleta ,   Research Center for Biomedis, National Research and Innovation Agency, Indonesia, Widoretno Widoretno ,   Research Center for Biomedis, National Research and Innovation Agency, Indonesia
Published: June 2024

The prevalence of communicable diseases in Indonesia is still high and causes morbidity and mortality in several Indonesian provinces. This cross-sectional study classified provinces based on the prevalence of seven communicable diseases: acute respiratory infections (ARI), pneumonia, diarrhea, filariasis, malaria, hepatitis, and tuberculosis (TB). The study analyzed the 2018 Indonesian Basic Health Research data. It is essential to categorize these diseases to identify regions with low, moderate, and high prevalence and the factors that affect them to facilitate the treatment of these diseases. Grouping provinces and influenced factors were analyzed using K-means, ANOVA, and stepwise regression. The results revealed that Group 1 shows a high prevalence, except for hepatitis and diarrhea. Group 2 demonstrates a moderate prevalence, excluding hepatitis and diarrhea, while Group 3 has a low prevalence. Improved access to primary healthcare services reduced the prevalence of pneumonia and TB, while using insecticide-treated mosquito nets for less than three years increased the prevalence of ARI and pneumonia. Adequate bedroom lighting reduced the prevalence of ARI, whereas being underweight in individuals over 18 increased it. In individuals aged 16–18 with short stature, there was an increase in the prevalence of hepatitis and malaria. Regularly draining the bathtub once a week and ensuring proper bedroom ventilation reduced the incidence of diarrhea. Using improved long-lasting insecticidal nets (LLINs) for mosquitos led to a decrease in filariasis cases. Specific factors influence each communicable disease and necessitate a multisectoral approach for effective treatment.
Linguistic and cultural images of Moscow and Warsaw in Russian and Polish language parodies
Authors: Spalek Oksana Nikolaevna
Published: June 2024

The subject of this study is the parodies of the Russian and Polish languages, containing ideas about Moscow and Warsaw. The material was proverbs and sayings recorded in the dictionary of V.I. Dahl "Proverbs of the Russian people" and the collection of Y. Krzyzanowski "Nowa księga przysłów i wyrażeń przysłowiowych polskich". The Paremiological Foundation plays a special role in preserving the cultural memory of the linguistic community, expresses the most important and stable stereotypes of national consciousness. At the same time, the ideas verbalized in the parodies can have both a universal, timeless character, and fix the features of the socio-historical context, the material and spiritual culture of society in a certain epoch. In the course of the research, the author identifies, analyzes and compares the components of the linguistic and cultural images of Moscow and Warsaw, verbalized in the parodies of the Polish and Russian languages. In this work, the method of synchronous description was used, as well as methods of semantic and linguistic-cultural analysis. The scientific novelty of this work lies in the multicomponent analysis and comparison of the expression of the image of Moscow and Warsaw in Russian and Polish paremiology. In the course of the study, it was possible to establish the multicomponence of linguistic and cultural images of Moscow and Warsaw. Russian and Polish parodies contain ideas about these cities as the centers of economic, political and cultural life in Russia and Poland. At the same time, the parodies express the traditional attitude towards Moscow and Warsaw as rich, beautiful cities with a high standard of living, developed trade, but at the same time expensive and dangerous. The parodies characterize the residents of Moscow and Warsaw, their habits and mores, and also refer to the role of individual streets and districts in the life of cities. The study also found that the Russian language parodies contain ideas about Moscow as a city associated with important events in the history of Russia, a city with rich architecture and certain relief features. The above-mentioned ideas about Warsaw were not recorded in the Polish language parodies.
Antecipação de referentes em DPS complexos com relativas preposicionadas
Authors: Augusto Marina Rosa Ana , Soto Marije , Forster Renê , Floripis Maria Clara Abend , Gameiro Veronica
Published: June 2024

Este estudo investiga, particularmente, o mapeamento antecipado do referente de um DP complexo, apresentando uma oração relativa preposicionada com para, ou seja, com papel temático de beneficiário. Explora-se a contribuição que o tipo de estratégia relativa utilizada (padrão ou cortadora) pode trazer para a antecipação do referente, dada a possibilidade de integração incremental de informação contextual visual e linguística precedente. Em um experimento de seleção de imagem, aplicado a 41 participantes, falantes cultos de português do Brasil, a ser reportado, apresentaram-se contextos visuais e linguísticos auditivos prévios em que um personagem participa de dois eventos distintos (um evento apresentado com verbo bitransitivo e um evento apresentado com verbo transitivo), envolvendo coparticipantes distintas. Busca-se verificar em que medida o uso, na sentença-teste auditiva, que segue os preâmbulos discursivos e visuais, de uma estratégia padrão da língua, na qual a preposição aparece precedendo o pronome relativo, poderia favorecer a antecipação do referente do DP complexo, em comparação à estratégia cortadora, em que a preposição não está presente. Empregou-se uma tarefa de correspondência sentença-gravura na qual a acurácia e o tempo de resposta foram considerados como variáveis dependentes. Ademais, objetivou-se verificar a influência de conhecimento de norma padrão e de memória de trabalho verbal no desempenho da tarefa. Solicita-se que tentem clicar o mais rápido possível na imagem descrita pela sentença contendo a relativa. Nossos resultados não indicaram uma vantagem do uso da relativa padrão sobre a cortadora para a antecipação do referente do DP complexo. No entanto, a acurácia da seleção da imagem foi significativamente melhor para esse tipo de relativa. Melhor desempenho no teste normativo e no teste de reading span foi associado a TRs mais rápidos e maior acurácia na relativa cortadora. Fatores que parecem influenciar esse quadro são complexidade da estrutura relativa, possível ambiguidade da relativa cortadora e a sensibilidade limitada do teste para flagrar essa possível antecipação.
Analyzing the immediate and carryover effects of neurodynamics on straight leg raise ranges among acute prolapsed intervertebral disc patients: A randomized control double-blind study
Authors: Bahuguna Durga , Agarwal Vaibhav , Bhat Ashwani , Pandey Sanjeev
Published: June 2024

Objectives:

Prolapsed intervertebral disc (PIVD) is a disease that occurs when the annulus fibrosus ruptures, which leads to an effusion of the nucleus pulposus. The straight leg raise (SLR) test is a neurological test that is used in the physical examination of patients with low back pain to ascertain whether the sciatic nerve has been affected due to irritation of the lumbosacral nerve root. The discomfort or pain caused by sciatic nerve compression can be significantly reduced by neurodynamic mobilization, which lowers inflammatory mediators. The study aimed to analyze the neurodynamic exercises’ immediate and carryover effects, including the static opener and four levels of sliders and tensioners on SLR ranges among acute PIVD patients.

Methods:

A total of 44 subjects with acute PIVD were randomly assigned into two groups. The experimental group (n = 22) received neurodynamics and the control group (n = 22) received conventional therapy. The outcome variables were the visual analog scale (VAS), pain site code (PSC), and SLR test, which were assessed at baseline, post-intervention, and after 72 h (carryover).

Results:

The experimental group showed positive significant effects on VAS score, PSC score, and SLR ranges, whereas the control group showed immediate effects on VAS score, PSC score, and SLR ranges, but the effects were not maintained for a longer duration (72 h).

Conclusion:

Neurodynamics, including the static opener and four levels of sliders and tensioners, showed significant immediate and carryover improvement in VAS, PSC score, and SLR ranges. However, the experimental group was significantly better at improving pain, PSC score, and SLR range than the control group.
Differences in merlin and p53 expression as a predisposing factor in orbital meningioma
Authors: Janah Raudatul , Rujito Lantip , Wahyono Daniel Joko
Published: June 2024

Objectives:

The behavior of orbital meningiomas is difficult to predict. The p53 tumor suppressor gene mutation and the neurofibromatosis 2 gene’s inactivation in the merlin formation are two of the several mechanisms that contribute to the development of tumors. This considers the comparison of merlin and p53 expression as an inclination to evaluate the orbital meningiomas.

Materials and Methods:

This investigation is an observational expository considered within the shape of cross-sectional (cross-sectional). The samples/objects of this study were 44 patients with orbital meningioma who had a clinical, radiological, and histopathological diagnosis at the anatomical pathology laboratory at Cicendo Eye Hospital and Hasan Sadikin Bandung in 2017–2020, then an immunohistochemical examination of merlin and p53 expression was performed.

Results:

The study indicated that there was no relationship between p53 expression and orbital meningioma grading, also there is no relationship between merlin expression and orbital meningioma grading. However, based on the analysis test results, grade 3 orbital meningiomas tended to have a positive p53 expression rather than a negative expression and tend to have a negative merlin expression instead of a positive.

Conclusion:

Meningiomas with negative merlin expression have a tendency to express positive p53. Likewise, the higher grade (grade 3) tends to express positive p53 and negative merlin, which may play a key role in tumorigenesis of orbital meningioma, hence, an added value for clinical information and behavioral descriptions of orbital meningioma itself.
Neurocognitive outcome post cranioplasty: The role of cerebral hemodynamics and cerebrospinal fluid dynamics
Authors: Agrawal Manish , Mishra Keshav
Published: June 2024

Background:

Cranioplasty has been useful in treating the symptoms associated with the “Sunken skin flap syndrome” post decompressive craniectomy, for which various mechanisms have been proposed. In this study, we aim to assess the changes in the cerebral blood flow and intracranial cerebrospinal fluid (CSF) dynamics post cranioplasty and correlate with the improvement in the neurocognitive status.

Methods:

Computed tomography perfusion and cine magnetic resonance imaging studies were done to study the changes in cerebral perfusion and CSF flow dynamics postcranioplasty. The cognitive status was assessed using Montreal cognitive assessment, mini-mental state examination, and frontal assessment battery scores in the preoperative period and at 1 and 6 months follow-up.

Results:

There was a significant change in cognitive status postcranioplasty, both at 1 and 6 months follow-up, which was associated with a significant improvement in cerebral blood flow, decreased mean transit time, and improvement in the mean and peak CSF flow velocities at the foramen of Magendie and aqueduct of Sylvius.

Conclusion:

Cranioplasty leads to a marked improvement in cerebral hemodynamics, which is more significant on the ipsilateral side. It also leads to increased CSF turnover and improved CSF circulation. Improved cerebral perfusion and, more importantly, CSF dynamics may be responsible for the demonstrable improvement in the neurocognition in the postcranioplasty period.
Holocord myelopathy misdiagnosed as neuromyelitis optica spectrum disorder (NMOSD): A unique case of dural arteriovenous fistula at the craniocervical junction along first spinal nerve
Authors: Iampreechakul Prasert , Sopchokchai Intouch , Wangtanaphat Korrapakc , Chuntaroj Songpol , Wattanasen Yodkhwan , Hangsapruek Sunisa , Lertbutsayanukul Punjama , Siriwimonmas Somkiet
Published: June 2024

Background:

Dural arteriovenous fistulas (DAVFs) at the craniocervical junction (CCJ) involving the first spinal nerve represent a particularly rare and challenging subtype of DAVFs, with holocord myelopathy secondary to cerebrospinal DAVFs being an exceedingly rare presentation.

Case Description:

We report the case of a 70-year-old woman who presented with progressive paraparesis over 2 weeks. Initial magnetic resonance imaging (MRI) of the spine showed extensive holocord myelopathy, leading to a misdiagnosis of inflammatory myelopathy and subsequent inappropriate steroid treatment at a local hospital, which exacerbated her neurological symptoms. On transfer to our institution and further evaluation with MRI and magnetic resonance angiography, a lower thoracic DAVF was initially suspected. However, comprehensive spinal angiography failed to localize the fistula, prompting cranial angiography, which ultimately identified a DAVF at the CCJ along the C1 nerve root, supplied by a small radiculomeningeal branch of the left vertebral artery. Successful management involved coagulation of the proximal draining vein, with follow-up imaging confirming complete fistula obliteration and resolution of the holocord edema.

Conclusion:

This case highlights the diagnostic and therapeutic challenges associated with DAVFs at the CCJ, particularly when presenting with holocord myelopathy. It underscores the importance of a high index of suspicion and the need for timely, accurate diagnosis and intervention to prevent permanent spinal cord damage in such rare and complex cases.
Discovery of a Novel Mutant-Selective Epidermal Growth Factor Receptor Inhibitor Using in silico Enabled Drug Discovery Platform
Authors: Igawa Hideyuki , Konst Zef A. , Therrien Eric , Shelley Mee , Koldsø Heidi , Bos Pieter H. , Negri Ana , Verras Andreas , Guo Jiaye , Dahlgren Markus , Levinson Adam , Parr Brendan T. , Kurhade Suresh E. , Latthe Prashant , Shetty Rajesha , Santhanakrishnan Sridhar , Amberg-Johnson Katherine , Futran Alan , Atsriku Christian , Pelletier Robert , Liu Zhijian , Bell Jeffery A. , Bhat Sathesh , Svensson Mats , Gerasyuto Aleksey I.
Published: June 2024

Despite the success of first, second and third generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) in treatment of non-small cell lung cancer (NSCLC) with classical EGFR mutations (L858R or Exon 19 deletions), disease progression often occurs due to the acquisition of additional mutations in the EGFR kinase domain that confer TKI resistance. Specifically, acquisition of both T790M and C797S resistance mutations results in an EGFR variant that is resistant to all approved EGFR TKIs. Herein, we report a physics-based computationally-driven lead identification approach which successfully identified structurally-unique imidazo[3.2-b]pyrazole derivatives as reversible inhibitors of EGFR classical mutations bearing both T790M and C797S. Importantly, they spare EGFR WT to avoid known EGFR WT-driven cutaneous toxicities. During profiling of imidazo[3.2-b]pyrazole derivatives, we elucidated the bioactivation mechanism causing CYP3A4/5 time-dependent inhibition (TDI) and found key modifications to suppress bioactivation and mitigate the TDI risk. Representative lead compound 31 inhibited EGFR L858R/T790M/C797S in biochemical assays with a Ki = 2.1 nM, and EGFR del19/T790M/C797S in a Ba/F3 cellular assay with a IC50 = 56.9 nM. Deuterated analog of 31 (38) demonstrated dose-dependent tumor growth inhibition in a Ba/F3 EGFR del19/T790M/C797S CDX model by 47% at 50 mg/kg BID and 92% at 100 mg/kg BID.
Template-assisted electrospinning and 3D printing of multilayered hierarchical vascular grafts
Authors: Zarei Moein , Żwir Marek J. , Michalkiewicz Beata , El Fray Miroslawa
Published: June 2024

Fabricating complex hierarchical structures mimicking natural vessels and arteries is pivotal for addressing problems of cardiovascular diseases. Various fabrication strategies have been explored to achieve this goal, each contributing unique advantages and challenges to the development of functional vascular grafts. In this study, a three-layered tubular structure resembling vascular grafts was fabricated using biocompatible and biodegradable copolymers of poly(butylene succinate)(PBS) using advanced manufacturing techniques. The outer layer was fabricated by template-assisted electrospinning utilizing 3D printed scaffold with a precise hexagonal pore design as the template, and the inner layer was coated with gelatin through perfusion. Cellulose nanocrystals (CNC) were incorporated into electrospun fibers to enhance mechanical properties. Gelatin coating was applied to the lumen using perfusion coating, resembling inner layer. Integration of 3D printed structures with electrospun fibers via template-assisted electrospinning, and gelatin coating resulted in a seamless multilayered scaffold. Mechanical testing demonstrated robustness, surpassing natural arteries in some aspects, while gelatin coating significantly reduced liquid leakage, ensuring leak-free functionality. Cytotoxicity assessment confirmed biocompatibility of processed materials with fibroblast cells, supporting potential for medical applications.
Multiconfigurational Surface Hopping: A Time-Dependent Variational Approach with Momentum-Jump Trajectories
Authors: Li Guijie , Shi Zhecun , Huang Lei , wang linjun
Published: June 2024

The Ehrenfest mean field dynamics and trajectory surface hopping have been widely used in nonadiabatic dynamics simulations. Based on the time-dependent variational principle (TDVP), the multiconfigurational Ehrenfest (MCE) method has also been developed and can be regarded as a multiconfigurational extension of the traditional Ehrenfest dynamics. However, it is not straightforward to apply the TDVP to surface hopping trajectories because there exists momentum jump during surface hops. To solve this problem, we here propose a multiconfigurational surface hopping (MCSH) method, where continuous momenta are obtained by linear interpolation and the interpolated trajectories are used to construct the basis functions for TDVP in a post-processing manner. As demonstrated in a series of representative spin-boson models, MCSH achieves high accuracy with only several hundred trajectory bases and can uniformly improve the performance of surface hopping. In principle, MCSH can be combined with all kinds of mixed quantum-classical trajectories, and thus has the potential to properly describe general nonadiabatic dynamics.
Neutron Vibrational Spectroscopic Study of the Acetonitrile:Acetylene (1:2) Cocrystal Relevant to Titan, Saturn’s Moon
Authors: Kramer Morgan , Daemen Luke , Cheng Yongqiang , Balderas-Xicohtencatl Rafael , Ramirez Cuesta Anibal , Brown Craig , Runcevski Tomce
Published: June 2024

Saturn’s moon Titan features a surface composed of various organic solids with pronounced compositional and structural diversity. On top of the icy core, the surface experiences temperature of ~93 K and pressure of ~1.45 atm. Under these conditions, most small organic molecules exist as solids and form Titanean minerals. Acetonitrile and acetylene are two of these molecules, which can form single-component molecular solids, but also a 1:2 binary cocrystal. Here we present a combined neutron vibrational spectroscopic study, neutron powder diffraction study, and theoretical modeling of the cocrystal and the corresponding single-phase solids. This combined study resulted in insightful spectra–structure–properties correlations for the cocrystal and the molecular solids. Furthermore, we observed quenching of the high-temperature form of acetonitrile in the presence of the cocrystal, which supports the possibility of the existence of metastable solids as minerals on Titan. The results presented in this study further the knowledge of the putative structure and composition of the surface of Titan, and, at the same time, contributes to better understanding of the fundamental thermodynamic properties of two of the smallest organic molecules in the Universe.
Synthesis of 2-Amino-2-Deoxy Sugars via Boron-Catalyzed Coupling of Glycosyl Fluorides and Silyl Ether Acceptors
Authors: Xu Yishu , Montgomery John
Published: June 2024

Whereas aminosugars are an important component in a variety of bioactive molecules, their stereoselective formation is made challenging by the Lewis basic nature of amino substituents. Additionally, the use of N-acyl protecting groups is often problematic due to competing formation of oxazolines during the glycosylation of 2-aminosugar derivatives. Herein, we report a boron-catalyzed strategy utilizing silyl ether glycosyl acceptors and 2-aminosugar donors that utilize the 2,2,2-trichloroethoxycarbonyl (Troc) protecting group for the C2 amino functionality in glycosyl fluorides. This modification allows for operationally simple, room-temperature glycosylations and features a rapid reaction profile that addresses some of the limitations in the synthesis of 2-amino-2-deoxy sugar containing glycosides. Tailoring the order of reactivity of the silyl acceptors enables one-pot iterative glycosylations, thus streamlining the synthesis of complex oligosaccharides while allowing fewer intermediates and purification steps.
Activation of the Keap1/Nrf2 pathway suppresses mitochondrial dysfunction, oxidative stress, and motor phenotypes inC9orf72ALS/FTD models
Authors: Au Wing Hei , Miller-Fleming Leonor , Sanchez-Martinez Alvaro , Lee James AK , Twyning Madeleine J , Prag Hiran A , Raik Laura , Allen Scott P , Shaw Pamela J , Ferraiuolo Laura , Mortiboys Heather , Whitworth Alexander J
Published: June 2024

Mitochondrial dysfunction is a common feature ofC9orf72amyotrophic lateral sclerosis/frontotemporal dementia (ALS/FTD); however, it remains unclear whether this is a cause or consequence of the pathogenic process. Analysing multiple aspects of mitochondrial biology across severalDrosophilamodels ofC9orf72-ALS/FTD, we found morphology, oxidative stress, and mitophagy are commonly affected, which correlated with progressive loss of locomotor performance. Notably, only genetic manipulations that reversed the oxidative stress levels were also able to rescueC9orf72locomotor deficits, supporting a causative link between mitochondrial dysfunction, oxidative stress, and behavioural phenotypes. Targeting the key antioxidant Keap1/Nrf2 pathway, we found that genetic reduction ofKeap1or pharmacological inhibition by dimethyl fumarate significantly rescued theC9orf72-related oxidative stress and motor deficits. Finally, mitochondrial ROS levels were also elevated inC9orf72patient-derived iNeurons and were effectively suppressed by dimethyl fumarate treatment. These results indicate that mitochondrial oxidative stress is an important mechanistic contributor toC9orf72pathogenesis, affecting multiple aspects of mitochondrial function and turnover. Targeting the Keap1/Nrf2 signalling pathway to combat oxidative stress represents a therapeutic strategy forC9orf72-related ALS/FTD.
HALIMA XUDOYBERDIYEVA: VOICE OF THE ASPIRATIONS AND UNFULFILLED DREAMS OF UZBEK WOMEN
Authors: Nabiyeva Nodira Saidovna Nabiyeva Nodira Saidovna
Published: June 2024

Halima Xudoyberdiyeva, a renowned Uzbek poet, dedicated her literary career to expressing the hopes, dreams, and challenges faced by Uzbek women. This article explores the themes and impact of Xudoyberdiyeva's poetry, focusing on her role as a voice for Uzbek women's experiences and aspirations. Through an analysis of her works and critical reception, the article highlights the poet's contributions to Uzbek literature and her advocacy for women's rights.
New Era Enterprise We-media Brand Communication Strategy
Authors: Xu Xichen
Published: June 2024

At present, information technology has been widely used in the daily lives of people, and social media has changed their daily living habits. In this context, the rapid development of we-media has become a hot issue in the current society, which brings new opportunities and challenges for corporate brand communication in the new era. Nowadays, people’s consumption habits have changed from the traditional offline to the combination of online and offline. In this regard, enterprises should constantly explore and innovate the concept and method of we-media brand communication. This paper will start from the importance of enterprise we-media brand communication, and analyze the characteristics and effective strategies of enterprise we-media brand communication in the new era.
Optimization of Primary School English Classroom Teaching under the Digital Background
Authors: Wu Yin
Published: June 2024

As digital technology is widely used in various fields, students are exposed to more and more information, and the way of learning knowledge has changed greatly. In primary school English teaching, teachers should combine the digital environment to optimize the classroom teaching structure and promote students’ independent learning. Based on this, this paper first analyzes the connotation of digital teaching and its application significance in primary school English curriculum, and then discusses relevant practical paths in combination with specific cases, to offer suggestions for the digital transformation of English teaching.
Study on the Training Model of the Combination of Production, University, and Research of Transportation Graduate Students
Authors: He Yongming , Zhang Wenhui , Gu Shuang
Published: June 2024

To solve the disjointed problems of teaching, research, and practice among schools, transportation planning departments, traffic management departments, and enterprises, a training model combining production, university, and research for transportation graduate students was established. The construction of a transportation engineering platform can provide a reference for the innovative training mode of engineering graduate students, and also provide ideas and means for the combination of production, study, and research of other majors. Under the operation of the scientific mode, it can achieve the goal of teaching and learning and the win-win situation of the school and enterprise to realize the effect of “one plus one is greater than two.”
Reform and Practice Path of Ideological and Political Teaching in College Network Marketing Course
Authors: Tan Jianqiang
Published: June 2024

With the proposal of the fundamental task of “cultivating morality and cultivating people”, ideological and political education in colleges and universities has ushered in a new wave of reform. In this context, ways to promote the continuous improvement of the ideological and political level of college students and cultivate their cultural literacy have become one of the teaching problems of colleges, universities, and teachers. In this regard, this article briefly analyzes the connotation of ideological and political teaching of network marketing, hoping to provide readers with some valuable reference.
The Optimization Methods of University Education Management in the Era of Big Data
Authors: Chen Guosong
Published: June 2024

With the development of education reform, the work of college education management should be further optimized. Teachers should actively introduce new ideas and methods of education management, to better stimulate the interest of students and teachers to participate in education management activities and improve the effect and quality of education management work. As a popular technical means, big data technology can greatly enrich the content of college education management, broaden the path of management work, and greatly promote the comprehensive level of college education management work. Given this, this paper will analyze the university education management work in the era of big data and put forward some optimization strategies for reference.
Analysis of Immersive Exhibition Based on Glasses-free 3D Technology
Authors: Liu Weiya
Published: June 2024

This article primarily examines glasses-free 3D technology and its application in immersive exhibitions. The article includes an analysis of glasses-free 3D technology and its applications, an examination of immersive exhibitions supported by glasses-free 3D technology, as well as the drawbacks of glasses-free 3D technology and its future development trends. It is hoped that this analysis can offer some insights into the prudent application of glasses-free 3D technology, aiming to achieve a compelling immersive exhibition experience.
Research on Optimization of the Studies Withdrawal System for Doctoral Students
Authors: Zheng Chuanfeng , Yang Xue
Published: June 2024

The studies withdrawal system of doctoral students is an important aspect of the modernization of higher education, and also an important measure to ensure the quality of doctoral cultivation and the level of education. Through the research on the process of doctoral students’ withdrawal, the necessity of doctoral students’ withdrawal and the implementation of the current situation are discussed, and the practical problems and reasons of the system are analyzed. The study also proposes to further improve the implementation rules of the process from the aspects of establishing and improving the policy guarantee and supervision process of the system, optimizing the management system of doctoral students in colleges and universities, increasing the publicity of the system, and so on, to ensure the implementation effect of the system.
Highly pathogenic avian influenza A(H5N1) virus infections on fur farms connected to mass mortalities of black-headed gulls, Finland, July to October 2023
Authors: Kareinen Lauri , Tammiranta Niina , Kauppinen Ari , Zecchin Bianca , Pastori Ambra , Monne Isabella , Terregino Calogero , Giussani Edoardo , Kaarto Riikka , Karkamo Veera , Lähteinen Tanja , Lounela Hanna , Kantala Tuija , Laamanen Ilona , Nokireki Tiina , London Laura , Helve Otto , Kääriäinen Sohvi , Ikonen Niina , Jalava Jari , Kalin-Mänttäri Laura , Katz Anna , Savolainen-Kopra Carita , Lindh Erika , Sironen Tarja , Korhonen Essi M , Aaltonen Kirsi , Galiano Monica , Fusaro Alice , Gadd Tuija
Published: June 2024

Highly pathogenic avian influenza (HPAI) has caused widespread mortality in both wild and domestic birds in Europe 2020–2023. In July 2023, HPAI A(H5N1) was detected on 27 fur farms in Finland. In total, infections in silver and blue foxes, American minks and raccoon dogs were confirmed by RT-PCR. The pathological findings in the animals include widespread inflammatory lesions in the lungs, brain and liver, indicating efficient systemic dissemination of the virus. Phylogenetic analysis of Finnish A(H5N1) strains from fur animals and wild birds has identified three clusters (Finland I-III), and molecular analyses revealed emergence of mutations known to facilitate viral adaptation to mammals in the PB2 and NA proteins. Findings of avian influenza in fur animals were spatially and temporally connected with mass mortalities in wild birds. The mechanisms of virus transmission within and between farms have not been conclusively identified, but several different routes relating to limited biosecurity on the farms are implicated. The outbreak was managed in close collaboration between animal and human health authorities to mitigate and monitor the impact for both animal and human health.
ACEH'S ECONOMIC TRANSFORMATION: SINCE RECEIPT OF THE ACEH SPECIAL AUTONOMY FUND, NOW AND IN THE FUTURE
Authors: Hadi Arifin A , Matriadi Faisal , Muchtar Darmawati
Published: June 2024

The Aceh economy is thought to have experienced a continuous transformation gap from year to year after receiving Aceh Special Autonomy Funds from the central government which has been increasing, starting from 3.59 T in 2008 to 8.36 T in 2019, for 12 years, with average expenditure -amount of 6.11 T per year, which must be prioritized in the areas of infrastructure, people's economic empowerment, poverty alleviation, education, social affairs, health and the unique features of Aceh. This research study uses a descriptive literature study method. Data collection was analyzed from literature such as books, journals, and articles related to the Aceh economy. The study and analysis results illustrate that the use of the Aceh Special Autonomy Fund still needs to meet its priority designation, meaning that the transformation of priority areas still needs to be revised and has been achieved thoroughly. Then, there are economic development activities and programs that have yet to meet the needs of life and moderately and dignifiedly increase the income and benefit of the people of Aceh. Recommend maintaining the privileges of Islamic Sharia by continuing Wali Nanggroe's authority as a unifier of Acehnese customs, determining sustainable policies to establish the Aceh Special Autonomy Fund Supervisory Board, reforming the Aceh economy to become the main gateway for international trade in the western region, building a sharia economy and sharia financial institutions, and developing a center for people's economic growth.
THE INFLUENCE OF THE BLOCK SYSTEM ON PROFESSIONAL ETHICS FOR ACCOUNTING GRADUATES AT POLITEKNIK ACEH
Authors: Hilmi Hilmi , Handayani Meutia , Fauziah Sri Rani , Kadriyani Emilda , Rismadi Rismadi , Ramadhaan Rizki , Fajar Muhammad Thariq , Wadznah Zaidatul
Published: June 2024

This study aims to determine the effect of the Block System on the professional ethics of Politeknik Aceh accounting graduates. In proving this, a qualitative method is used. The analytical method used is simple linear regression analysis using SPSS 25. The data used in this study are primary and secondary. The data collection method used was a questionnaire. The sample for this study was 50 graduates of Accounting at the Politeknik Aceh as respondents consisting of 3 graduates or graduates in 2020, 2021, and 2022. The results of this study indicate that the block system has a partial effect on the professional ethics of accounting graduates at the Politeknik Aceh.
DESIGNING ADAPTIVE CLOTHING FOR DIFFERENTLY ABLED CHILDREN USING WHEELCHAIR
Authors: Mahajan Sharina , Pargai Deepti , Krishma
Published: June 2024

Adaptive clothing is made for patients who struggle to wear and remove off clothing because of disabilities or restricted mobility. This adaptation still accommodates their difficulties while allowing persons with disabilities to dress like their counterparts. It was discovered that the wearer's freedom and independence were increased by this type of adaptable clothes. As the wearer's sense of autonomy and control over their body develops, they are better able to participate fully in their community. This kind of adaptable clothing design increases psychological comfort in addition to physiological comfort by improving the wearer's self-confidence. This study's main objective was to acquire qualitative data regarding the clothing needs of kids with impairments. An open-ended interview schedule with boys of 10-15years of age group and their care takers was used. Data was gathered addressing the physical effects of the handicapping condition that relate to clothes and dressing, the ways of procuring clothing, dressing considerations, clothing needs, and clothing issues that may arise when a support device is employed. A restricted physical movement was observed in every case, and the wheelchair was the most common support equipment. After analyzing the problem area for putting and taking off clothes, the adaptive garments were designed. The designed garments were ranked by the experts from designing field. The collection was found to be highly appropriate. The top ranked design was constructed for final wear trial. It has been discovered that wearing this type of adaptable apparel increases the wearer's freedom and independence. Adaptive clothing increases the wearer’s sense of autonomy and control over their body means that they can more meaningfully participate in their community.
THE IMPACT OF HINDI CINEMA ON ALTERING THE ADULTS’ PERCEPTION TOWARDS SOCIETAL STEREOTYPES: A STUDY OF DELHI NCR
Authors: Singh Karan , Pasha Mohammad Aamir , Rai Shivendu Kumar
Published: June 2024

Hindi cinema, with its immense popularity and pan-India reach has long been recognized as an influential socio-cultural force in the country. Through propagation of enduring stereotypes in films, it contributes to shaping and reinforcing the attitudes and perceptions of audiences regarding gender roles, communities, professions and societal values. This study aimed to examine the impact of exposure to stereotypical Hindi cinema on altering adults’ perceptions towards commonly accepted societal stereotypes in the Delhi NCR region.A sample of 217 adults aged 18-35 above years was surveyed using questionnaires to assess cinema viewership patterns, endorsement of societal stereotypes portrayed in Hindi movies. The findings highlight the powerful influence Hindi cinema wields in combating regressive stereotypes in society especially among vulnerable sections like the rural poor with limited education. But rising education levels are breeding resistance to such stereotyped beliefs. The paper recommends that Hindi filmmakers should consciously avoid harmful stereotypes and attempt progressive portrayals of gender, caste, class and professions. Responsible cinema can play a transformative role in promoting egalitarian attitudes aligned with India’s development goals.
Sustainability status of People's Salt Pond Businesses in the coastal area of Labakkang District Pangkep Regency
Authors: Rauf Abdul , Yusuf Kamil , Yunus Muhammad , Rauf Andi Muhammad Ilham
Published: June 2024

Labakkang District is the only coastal district in Pangkep Regency that has the potential for salt pond business activities. The people's salt farming business is a business that has been carried out by the people in this area for a long time, but there are several problems, namely the large amount of unused land, low quality of salt, low selling price and lack of market absorption, therefore a study is needed to see the sustainability status of the business. the. This research aims to determine the sustainability status of people's salt businesses in Labakkang District, Pangkep Regency. The analytical method used in this research is sustainability status analysis with "SIOS" (sustainability index of salt) modified from the Rapfish analysis program. to find out the sustainability status of the people's salt business. Based on the results of the analysis of sustainability status using the sustainability index approach, it shows that the value of the ecological dimension (85.98), the economic dimension (80.79) and the institutional dimension (75.91) are all included in the sustainable category, while the value of the social dimension is (57.63). falls into the moderately sustainable category.
Physico-chemical characteristics of sea urchin shell calcium (Diadema setosum) on Barrang Lompo Island
Authors: Hasrianti Hasrianti , Harianti Harianti , Awaluddin Awaluddin , Khairiyah Zul
Published: June 2024

Calcium is a mineral that can be found in the shells of sea urchins. Calcium supplementation in pill form is commonly encountered within the community, derived from both animal and vegetable sources. The objective of this study is to investigate the physico-chemical properties of calcium derived from the shells of the sea urchin species Diadema setosum. The research was conducted between April 2023 and June 2023, involving sample collection on BarrangLompo Island and subsequent testing at the Chemical Laboratory of Pangkep State Agricultural Polytechnic. The study methodology employed entailed conducting experiments within a controlled laboratory setting where distinct treatment media were utilized. Specifically, the treatments employed were denoted as Treatment A, characterized by a temperature of 1000 °C, and Treatment B, characterized by a temperature of 500 °C.The findings of the study conducted on calcium derived from sea urchin shells (Diadema setosum) revealed that the calcium exhibited two distinct colors, namely dark brown and light brown. Additionally, some samples possessed an odor, while others were odorless. Furthermore, the texture of the calcium was observed to be smooth. The average yield values for treatment A and treatment B were determined to be 1.49 and 1.80, respectively. Moreover, the average water content values for treatment A and treatment B were found to be 1.29 and 1.06, respectively. Lastly, the average calcium content values for treatment A and treatment B were measured to be 83.30 and 78.20, respectively. Based on the results of statistical analysis, it is evident that there is no statistically significant disparity observed in the yield, water content, or calcium content of sea urchin shell calcium flour (Diadema setosum).
Social capitals as village building potential (Case study: Matamppa Walie Village Community in Bone Regency)
Authors: Sabiq Muhammad , Sakaria Sakaria , Arisnawawi Arisnawawi
Published: June 2024

Kinship among the people of Mattampa Walie village in Bone can be created because values, norms and trust between fellow communities are still upheld. The concept of social capital has three important elements, namely trust, values and networks, which can place special emphasis on the causal relationship between social capital and community welfare. The research uses a qualitative approach with a case study type. Data collection was carried out using observation, interview and documentation techniques. Data analysis techniques are carried out by reducing data, presenting data and drawing conclusions. The research results show that strong social capital, supported by trust, solid social networks, and the values of mutual cooperation, is an important foundation in strengthening solidarity and togetherness in the Mattampa Walie Village community. It is hoped that this will be an impetus for better development, as well as increasing the welfare and resilience of families in preparing strong human resources.
Shelf-life analysis of lawa mairo frozen as tradisional food from South Sulawesi
Authors: Rasmini Rasmini , Susilowati Aryanti , Khairiyah Zul
Published: June 2024

This study aims to determine the frozen shelf life of Lawa’ Mairo by analyzing the total plate number. This research was carried out in June 2022, the manufacture and testing of Lawa 'Mairo was carried out at the Laboratory of the Fishery Product Quality Application Center, Makassar, South Sulawesi. This research is classified as quantitative research with experimental method, with four treatments (storage time). Three lengths of frozen storage, namely 1 day, 3 days, and 5 days, as well as 0 days as control (fresh lawa' mairo). Data analysis used the t test to see the effect of storage time on microbial growth and the effect of sensory values on treatment. The results of this study indicate that the shelf life of frozen lawa' mairo from ALT testing that has been carried out is classified as safe for consumption. Lawa’ mairo can last as long as in cold or frozen conditions. Based on the t test, the storage time was declared to have a significant effect on microbial growth in frozen lawa' mairo products. The results of the sensory test on the hedonic scale showed that the panelists' preference level was highest on fresh lawa' mairo (0 days storage). Based on the panelists' assessment of frozen lawa' mairo, there was a change in taste due to an oxidation process during the storage period. Based on the t test performed, it is stated that it has a significant effect between the sensory values of the hedonic scale on the storage time (p<0.05).
Optimizing Arabic Text Listening Skills through the Numbered Head Together Strategy
Authors: Mizan Khairul , Muassomah Muassomah , Zoni Lapas , Alkampary Ahmad Iqbal , Muhlis Wachida
Published: June 2024

The study aimed to explore the application of the NHT strategy in optimizing the learning of Arabic text listening skills and to describe students' responses to its use. A lack of practice in listening results in difficulties in interacting. These difficulties are also caused by students' lack of motivation and interest, as well as a lack of vocabulary and limited understanding of sentence structure. Therefore, an alternative is needed to minimize the problem. The strategy is called Numbered Head Together (NHT). This research employed a quantitative approach with a survey method. Data were collected through observations, interviews, and questionnaires. Questionnaire data was analysed using SPSS 25. The results of the study elucidated six steps in the application of the NHT strategy: a) material preparation; b) numbering, where the teacher formed groups and assigned each group member a number from 1-5; c) listening to the text, where students were asked to listen to the text either using audio-visuals or directly from the teacher; d) asking questions, where each question given by the teacher had an identification number; e) discussion process, where students were asked to discuss the given questions; f) submission of discussion results, where students with numbers matching the question number had the responsibility to answer the question. Students' responses to the NHT strategy, measured by indicators such as interest, involvement, and perceived impact, obtained a score of 1,505 out of a maximum of 1,725, with a percentage of 87.24% (very satisfying). This research provides practical implications for improving students' learning motivation and response. Its contributions include a better understanding of the effectiveness of this strategy and providing empirical evidence for teachers to develop more effective learning strategies.