bluuebunny/crossref_metadata_2025 huggingface dataset:
Uncatalysed Oxidative C‒H Amination of 9,10-Dihydro-9-Heteroanthracenes: A Mechanistic Study
Authors: van Leest Nicolaas P. , grooten Lars , Ivar van der Vlugt Jarl , de Bruin Bas
Published: February 2019

A new method for the one-step C‒H amination of xanthene and thioxanthene with sulfonamides is reported, without the need for any metal catalyst. A benzoquinone is employed as a hydride (or two-electron and one-proton) acceptor. Moreover, a previously unknown and uncatalysed reaction between iminoiodanes and xanthene, thioxanthene and dihydroacridines (9,10-dihydro-9-hetero-anthracenes or dihydroheteroanthracenes) is disclosed. The reactions proceed via hydride transfer from the heteroarene substrate to the iminoiodane or benzoquinone, followed by conjugate addition of the sulfonamide to the oxidized heteroaromatic compounds. These findings may have important mechanistic implications for metal-catalysed C‒H amination processes involving nitrene transfer from iminoiodanes to dihydroheteroanthracenes. Due to the weak C‒H bond, xanthene is an often-employed substrate in mechanistic studies of C‒H amination reactions, which are generally proposed to proceed via metal-catalysed nitrene insertion, especially for reactions involving nitrene or imido complexes that are less reactive (i.e. less strongly oxidizing). However, these substrates clearly undergo non-catalysed (proton-coupled) redox coupling with amines, thus providing alternative pathways to the widely assumed metal-catalysed pathways.
Ab Initio Molecular Dynamics Simulations of the Ferroelectric-Paraelectric Phase Transition in Sodium Nitrite
Authors: Dürholt Johannes P. , Schmid Rochus
Published: February 2019

This paper reports on the first ab initio molecular dynamics study of the ferroelectric Sodium Nitrite, shedding light on its order-disorder phase transition. The remnant polarization Pr was calculated using a Mulliken population analysis and maximally localized Wannier functions. Especially the Wannier based model is in excellent agreement with experimental findings and previous Berry phase calculations. The simulations predict a ferroelectric Curie temperature Tc between 400 K and 450 K in good agreement with the experimental value of 437 K. In addition, the anomalous lattice behavior (shrinking of the c-axis) during the phase transition is reproduced. The crystal field effect in the material could be quantified by investigating the molecular dipoles based on the maximally localized Wannier functions and the intermolecular charge transfer by analysing the Mulliken charges. In agreement with earlier experimental and theoretical findings, the polarization reversal mechanism was found to be dominated by a c-axis rotation of the Nitrite ions. The molecular insight into such a simple and prototypical material serves as a basis for a further development of more complex crystalline order-disorder ferroelectrics.
21st Century Learners: Changing Conceptions of Knowledge, Learning and the Child
Authors: Hirschman Kate , Wood Bronwyn
Published: February 2019

The term ‘21st century learner’ emerged at the turn of the millennium and evoked a certain type of digitally-agile and self-driven learner. These ideas about 21st century learners have been widely and uncritically adopted in New Zealand policies and practices in recent years. This paper examines the origins and substance of this term against the backdrop of globalisation and Knowledge Economy discourses and emerging ideas of ‘digital natives’. It considers the implications of these ideas on conceptualisations of the child, the development of deep learning, the impact on relationships between adults/teachers and students and on social equity. It concludes by suggesting that the term 21st century learner needs on-going critique if we want critical, informed citizens in our democracy.
Influencing Gender Specific Perceptions of the Factors Affecting Women’s Career Advancement Opportunities in the United States
Authors: C. Taliaferro Kevin
Published: February 2019

This research investigates the sociological, psychological, and physiological factors known to affect women’s career advancement opportunities. It examines how awareness and knowledge shared through the #MeToo (hashtag Me Too) movement influenced gender specific perceptions about the factors affecting women’s workplace opportunities. Finally, it recommends measures to alter the divergent gender perceptions that remain an obstacle to gender equality in the workplace. The researcher conducted a mixed method experimental study by comparing pre- and post-treatment interview and survey data to determine how much awareness and knowledge shared through the #MeToo mass media events impacted gender specific perceptions of women’s equality struggles in the workplace. With outcomes from three independent qualitative and quantitative investigations aligning, the researcher concluded the overall statistical results demonstrate a strong impact on men’s and women’s perceptions and a largely reduced gender perception gap following the #MeToo media events.
A CASE OF SUCCESSFUL TREATMENT OF A PATIENT WITH HIGH PULMONARY HYPERTENSION BY IMPLANTATION OF AN OCCLUDER IN AN ATRIAL SEPTAL DEFECT
Authors: Korzh D. A. , Samko A. N. , Gorbunov M. G. , Larionov A. A. , Gaponov D. P. , Agafonov D. V. , Tarasov D. G.
Published: February 2019

Aim: the purpose of this publication is to demonstrate the safety and efficacy of the endovascular method of treatment for long-existing, neglected, and fairly common congenital heart defects such as an atrial septal defect with high pulmonary hypertension.Material and Methods. We present a clinical case of the successful X-ray endovascular treatment of a 48-year-old female patient with a high pulmonary hypertension diagnosed with congenital heart disease, atrial septal defect. Clinical and instrumental examination included standard resting electrocardiography, echocardiography, and catheterization of the right heart and the pulmonary artery. Surgical treatment consisted in an X-ray endovascular implantation of the 40-mm atrial septal defect closure device via the transfemoral access. Post-operative follow up care lasted for 15 months.Results. Echocardiography study showed the left ventricular ejection fraction of 53 mL; congenital heart disease was characterized by 2.5-cm secondary central atrial septal defect and a variable pressure release. Pulmonary artery systolic pressure was 120 mmHg. Catheterization of the right heart and the pulmonary artery showed blood flow with the presence of leftto-right shunting equal to Qp/Qs=2.0/1. An X-ray endovascular atrial septal defect surgery was conducted in an X-ray operation room via a standard transfemoral access. The surgery consisted in X-ray endovascular atrial septal defect occlusion with an implantation of an atrial septal defect closure device with 40-mm neck diameter. Intraoperative echocardiography study showed that the closure device was placed correctly with no signs of residual bleeding. The final echocardiography performed in three days showed the condition after atrial septal defect closure device implantation. The defect was tightly closed. Pulmonary artery systolic pressure was 83 mmHg. Hospital stay lasted for three days. Follow-up echocardiography study at 15 months showed the condition after atrial septal defect closure device implantation. The defect was tightly closed. Pulmonary artery systolic pressure was 46 mmHg.Conclusion. There are currently two types of treatment: open surgery such as suturing or plastic  urgery with extracorporeal blood circulation and X-ray endovascular occlusion of the atrial septal defect by implantation of a special device. The X-ray endovascular treatment of an atrial septal defect with a closure device implantation is a highly effective and safe procedure. The main advantages of this method are as follows: surgery does not require anesthesia, incision, and heart-lung bypass whereas reimplantation and repositioning of the device is always feasible.
DIAGNOSTIC ULTRASOUND ALGORITHMS FOR ACUTE CARDIOVASCULAR EVENTS
Authors: Nartsissova G. P. , Volkova I. I. , Zorina I. G. , Malakhova O. Yu. , Prokhorova D. S. , Zholobova N. V. , Latortseva T. A.
Published: February 2019

The article describes the principles of ultrasonic diagnosis of acute cardiovascular events including focused echocardiography protocol. Authors present brief diagnostic ultrasound algorithms for some acute cardiovascular events and describe the clinical manifestations and the major echocardiographic signs to help the practical doctor to quickly establish the precise diagnosis in emergencies.
RADIONUCLIDE METHODS FOR DIAGNOSIS AND TREATMENT ASSESSMENT OF BREAST CANCER
Authors: Vernadsky R. Yu. , Medvedeva A. A. , Garbukov E. Yu. , Chernov V. I. , Slonimskaia E. M.
Published: February 2019

Molecular imaging is a multimodal discipline for visualizing biological processes at the subcellular level in vivo. These diagnostic methods could be potentially used for screening and staging of cancer as well as for monitoring of treatment. Formerly, mostly anatomical information played key role in medical visualization. Now, molecular visualization allows improving diagnostic parameters of standard diagnostic methods. Molecular imaging allows not only for localization of tumor, but also for visualization of biological processes that influence tumor behavior and response to therapy. This review reflects the potential role of radionuclide methods and radiopharmaceuticals in diagnostic and assessment of tumor response. The paper covers indications and capabilities of dedicated nuclear breast imaging systems such as breast-specific g-imaging and positron-emission mammography. The accuracy of different methods was analyzed. The analysis showed that new technological solutions allow to significantly increase informativeness of examinations through improved spatial resolution compared to whole-body imaging cameras. Molecular imaging is useful for neoadjuvant chemotherapy response monitoring and is highly sensitive for prediction of non-responsiveness during treatment of breast cancer. The sensitivity of molecular breast imaging is comparable with that of magnetic resonance imaging, but has higher specificity. Molecular imaging may play a great potential role in the diagnostic algorithm for breast cancer.
QUALITY OF CARE FOR PATIENTS WITH MYOCARDIAL INFARCTION WITH ST SEGMENT ELEVATION. REAL CLINICAL PRACTICE OF THE SIBERIAN INVASIVE CENTER
Authors: Demianov S. V. , Syrkina A. G. , Vyshlov E. V. , Maximov I. V. , Baev A. E. , Markov V. A. , Karpov R. S. , Ryabov V. V.
Published: February 2019

Background. There are many quality indicators for evaluation of quality of care in patients with myocardial infarction in the USA and Europe, but no such indicators exist in Russia.Material and Methods. This retrospective study included 475 STEMI patients, admitted within the first 12 hours during 2016. The baseline characteristics and treatment of our STEMI patients were compared with the OPERA register (France). The quality of care in STEMI patients was assessed using the quality criteria of the Association of Acute Cardiovascular Care of the European Society of Cardiology. Thrombolytic therapy, primary PCI, cardiogenic shock, pulmonary edema, acute LV aneurysm, and acute psychotic disorders were endpoints for a comparative assessment of quality of care in different age groups.Results. The following was more frequent among patients of our center: female, history of MI, hypertension, dyslipidemia and smoker. Our patients were less likely to receive primary PCI and GP IIb/IIIa inhibitor, but more often thrombolytic therapy, LMWH, aspirin, inhibitor P2Y12, beta-blocker, ACEI/ARBs and statins. All eligible STEMI patients received reperfusion and recommended medication, but hospital mortality was higher than in the OPERA register (7.4% versus 4.6%; p<0.05). Senile STEMI patients are less likely to undergo invasive reperfusion due to severe comorbidity, dementia and acute psychotic disorders, which leads to a manifold increase in hospital mortality.Conclusion. It is necessary to develop new devices for PCI of calcinated lesions, and methods for neuroprotection to overcome the existing barriers to ensure high-tech care in senile STEMI patients.
COMPARATIVE ANALYSIS OF DEMOGRAPHIC, ANAMNESTIC, CLINICAL-LABORATORY AND INSTRUMENTAL DATA IN PATIENTS WITH MYOCARDIAL INFARCTION WITH AND WITHOUT OBSTRUCTIVE LESION OF CORONARY ARTERIES
Authors: Kruchinova S. V. , Kosmacheva E. D. , Porkhanov V. A.
Published: February 2019

Objective: to give a comparative characterization of myocardial infarction with and without obstructive lesion of coronary arteries.

Material and Methods. The study involved 4639 patients included in the first total register of acute coronary syndrome in the Krasnodar Territory for the first 12 months of register operation. A comparative analysis of patients with myocardial infarction with obstructive lesion and without obstructive lesion of coronary arteries was performed.

Results. Between November 2016 and November 2017, 4453 patients with myocardial infarction with obstructive coronary disease, including 2261 men (50.8%) and 2192 women (49.2%) were enrolled in the register. The mean age of patients was 68.3±12.03 years (69.3±3.42 years in men; 63.4±7.35 years in women). The criteria for myocardial infarction without obstructive coronary artery disease were present in 186 people (4.1%), including 72 men (38.7%) and 114 women (72.3%). The average age of the patients was 54.2±4.53 years; age of men with myocardial infarction without obstructive coronary disease was 56.3±3.52 years; age of women was 52.1±3.12 years. The article presents a detailed comparative analysis of demographic, medical history, clinical-instrumental, and laboratory data of these patient groups. 

Conclusion. Compared with patients who had obstructive coronary changes, the cohort of patients with myocardial infarction without obstructive lesions of the coronary arteries was younger and included more female patients; among the risk factors in this group, smoking and arterial hypertension were significant; the rates of newly diagnosed diabetes mellitus and Q-positive myocardial infarction were higher. According to the analysis of echocardiographic data, significant decrease in global contractility of the left ventricular myocardium was less common; analysis of laboratory data showed that patients more often had low platelet count.
ESTIMATION AND PROGNOSTIC VALUE OF THE PATIENTS SIMPATOVAGAL STATUS IN THE ACUTE PERIOD OF MYOCARDIAL INFARCT WITH ST SEGMENT ELEVATION
Authors: Oleynikov V. E. , Dushina E. V. , Lukyanova M. V. , Barmenkova Yu. A. , Moiseeva I. Y.
Published: February 2019

The aimof the study was to analyze the impact of the status of cardiac autonomic nervous regulation on the fragmentation activity, development and progression of heart failure, and the long-term prognosis in patients with early ST segment elevation myocardial infarction.Material and Methods. The study included 143 subjects; 54 healthy volunteers were examined to identify normal values of heart rhythm variability parameters. The observation group comprised 89 patients with ST segment elevation myocardial infarction who underwent 24-hour ECG monitoring at day 7 to 9 as well as at 24 and 48 weeks with follow up assessment of heart rate variability and late ventricular potentials. At the time points, the levels of brain natriuretic peptide and highly sensitive C-reactive protein were determined. Patients underwent a 6-min walk test every 12 weeks. The development of repeated cardiovascular events has been monitored as an end-point. Patients were assigned to two groups according to results of heart rhythm variability analysis at day 7–9 after onset of ST segment elevation myocardial infarction: group 1 had normal heart rate variability; group 2 had increased sympathetic impact on rhythm.Results. In group 1, a pronounced regression of the brain natriuretic peptide level was registered 24 week after onset of ST segment elevation myocardial infarction. The value of C-reactive protein decreased in all groups. A favorable transformation of the indices reflecting the fragmentation activity — high-frequency low-amplitude and root mean square — of the myocardium was recorded only in the group with normal heart rate variability parameters. The risk of repeated cardiovascular events during 48 weeks after ST segment elevation myocardial infarction was significantly higher in the group with dominant sympathetic activity than in the group with normal status of the autonomic nervous system.Conclusion. Hypersympathicotonia in the acute period of ST segment elevation myocardial infarction was associated with an increased relative risk of repeated cardiac events and negatively affected the dynamics of laboratory parameters indicative of heart failure development and progression.
Treatment of neuro-invasive listeriosis: an overview
Authors: Gudeikaitė P. , Valaikienė J. , Mameniškienė R.
Published: February 2019

Increasing mortality and morbidity rates of neurolisteriosis in Lithuania and Europe require methodological standardized treatment and a rapid response to the patient’s serious condition. Listeria monocytogenes is an aerobic gram-positive bacillus that can cause invasive listeriosis in humans, which most commonly affects the central nervous system. Clinically, neurolisteriosis occurs as meningoencephalitis, which is associated with the highest mortality rate in patients with severe conditions. The most at-risk populations are pregnant women, neonates, people over 65 years of age, and patients with chronic diseases or using immunosuppressive drugs. In case of suspected acute meningitis, encephalitis or meningoencephalitis in these individuals, it must be considered that the pathogen can be Listeria monocytogenes, which is resistant to the therapy of cephalosporins. First-line recommended therapy is a combination of amoxicillin and gentamicin intravenously. If the patient is allergic to beta-lactams, therapy of co-trimoxazole is recommended. The administration of dexamethasone against neurolisteriosis increases mortality rate. The article reviews the clinical manifestation and diagnostic criteria of neuroinvasive listeriosis and provides treatment recommendations.
Social cognition functions in persons with epilepsia
Authors: Jasionytė G. , Jasionis A. , Mameniškienė R.
Published: February 2019

This review article aims to present and provide concise information on the social cognitive functions in people with epilepsy. Social cognition is one of the six major cognitive domains, according to DSM-V, and is crucial for interpersonal communication. Major subdomains of this domain are recognition of emotions and theory of mind (understanding of mental states (emotions, beliefs, intentions and desires) of other people). Deficits of social cognition in epilepsy have been described by various researchers and are thought to be independently related with worse quality of life of people with epilepsy. We introduce the main social cognitive functions – recognition of emotions and theory of mind, their development and commonly used cognitive tasks to evaluate them. Further we provide summarized information on the deficits in social cognition in epilepsy and discuss main demographic and clinical correlates. Last paragraphs are concerned with special features of social cognition in major types of adult epilepsy and possible future interventions.
Treatment options for Leber hereditary optic neuropathy
Authors: Povilaitytė I. , Liutkevičienė R.
Published: February 2019

Leber hereditary optic neuropathy (LHON) is the most common hereditary optical neuropathy caused by primary mutations in mitochondrial DNA. LHON manifests as opticnerve atrophy and loss of central vision. In about 70% of LHON cases three major mutations in mitochondrial DNA: 11778G>A/ND4, 3460G>A/ND1 and 14484T>C/ND6 are detected. Literature also describes more than 18 novel mtDNA mutations associated with LHON and the dysfunction of mitochondrial electron transport chains. Due to this dysfunction, ATP synthesis decreases and the level of oxidative stress in ganglion cells of the retina increases, which leads to cell degeneration and apoptosis.In this article, we review the main manifestations of Leber hereditary optic neuropathy and its treatment options.
Relevance of anaesthesia type on early neurological outcome in acute ischemic stroke patients undergoing mechanical thrombectomy
Authors: Šalaševičius L. , Vilionskis A.
Published: February 2019

Background. Conscious sedation (CS) and general anaesthesia (GA) are types of anaesthesia used during mechanical thrombectomy (MTE). Currently, there are no guidelines on which type of anaesthesia to choose during MTE. Retrospective studies suggest that GA is associated with worse clinical outcomes, while latest clinical studies show no such difference.Materials and methods. Acute stroke patients treated in two Vilnius hospitals and undergoing MTE were included. Patients were divided into two groups according to the type of anaesthesia: general anaesthesia (GA) and conscious sedation (CS). Demographic, clinical and logistic data were evaluated. Primary end point was good outcome 24 hrs after MTE. Safety of the procedure (7-day mortality and symptomatic intracerebral haemorrhage (sICH)) was also evaluated.Results. 248 patients were included in the analysis. 105 patients (42.3%) received GA and 143 (57.7%) – CS. Baseline data was similar in both groups, except for atrial fibrillation (55.9% in CS vs 37.1% in GA, p=0.003) and bridging therapy (66.4% in CS vs 46.7% in GA group, p=0.003). Good outcome 24 hrs after MTE was achieved in 51.4% (n=54) patients in GA group and 58.7% (n=84) patients in CS group (p=0.252).There was no difference in 7-day mortality and sICH between the study groups. Periprocedural arterial blood pressure levels were significantly lower in GA group (p<0.05). Binary logistic regression analysis revealed that independent factors of good outcome were time from arrival to the hospital to recanalization and successful recanalization.Conclusions. Type of anaesthesia does not influence early clinical outcome or safety of mechanical thrombectomy. Further studies are needed to evaluate the relevance of anaesthesia type and to determine the prognostic factors of clinical outcome after MTE.
Pushing the boundaries of mechanical thrombectomy protocol for acute stroke management: two case reports
Authors: Želdakova J. , Motiejūnas G. , Jatužis D.
Published: February 2019

Stroke is a severe disease causing long-term disability. Mechanical thrombectomy is an effective treatment method, which significantly improves patients’ outcomes if applied according to strict inclusion and exclusion criterias. However, more recent studies show, that mechanical thrombectomy may be a safe and effective method even if used in disregard of some classical criterias. In this article, two case reports are presented. In both cases, mechanical thrombectomy was successfully used beyond the protocol.
Cerebral nocardiosis: case report and literature review
Authors: Šalaševičius L. , Kvaščevičius R.
Published: February 2019

Background. Cerebral nocardiosis is a very rare opportunistic infection of the brain, accounting for only up to 2% of all cerebral abscesses. Nocardial infections are most common among immunocompromised patients, although there are reports of nocardiosis in immunocompetent patients as well. Diagnosis is difficult, because nocardiosis is insidious in its clinical course, there are no specific laboratory or clinical findings, and the complete diagnosis is often reached only after bacteriological culture tests of the pus obtained during surgical excision.Case report. In this article we report a case of cerebral nocardiosis in 80-year old male with no immunodeficiency. Nocardiosis was diagnosed only with microbiological culture test after the surgical intervention.Conclusions. Diagnosing cerebral nocardiosis is difficult and the treatment is long-term and aggressive. In this case, a radical surgical excision of the cerebral abscess was performed and the treatment of possible primary odontogenic site of infection and a long-term (21 months) antibiotic therapy with Biseptol (Trimethoprim – Sulfamethoxazole) were initiated, resulting in complete recovery and return to good quality of life.
FINITE ELEMENT ANALYSIS ON DYNAMIC CHARACTERISTICS OF THE BUILDING FRAME
Authors: Кравченко Галина , Kravchenko Galina , Труфанова Елена , Trufanova Elena , Тронин Дмитрий , Tronin Dmitriy , Гунба Аслан , Gunba Aslan
Published: February 2019

The article deals with the study of the dynamic characteristics of the building frame by finite element method, using the method of regulating the stiffness of the system. The spectrum of frequencies and forms of natural vibrations of the building frame is obtained. The pulsation component of the wind load on the two main axes of the building is determined and a static calculation is made taking into account this load. Different variants of the frame modeling differed in the thickness of floor slabs and stiffening diaphragms. Variation of the geometric characteristics of the elements of the frame of the building allowed to choose the best option of the design scheme. The level of dynamic comfort is estimated by the results of the analysis of acceleration of the upper floor of the frame.
BEARING CAPACITY OF MODEL FOUNDATIONS ON SANDY GROUNDS
Authors: Евтушенко Сергей , Evtushenko Sergey , Скибин Геннадий , Skibin Gennadiy , Чутченко Светлана , Chutchenko Svetlana
Published: February 2019

The article continues the review of experimental studies conducted by the scientific school of soil mechanics of Novocherkassk Polytechnic Institute from 1962 to the present time. Studies of the bearing capacity of the sand base were carried out on various models of line, round, stand-alone and under the grid columns (plate).
The practice of implementing project management tools in housing construction, or how to reduce construction time by 17% in a year and a half
Authors: Искаков Тимур , Iskakov Timur
Published: February 2019

The article describes the successful implementation of project management tools in housing construction. Emphasis was placed on time management, risk management and the use of lessons learned. The company Bi-Group has successfully applied the MS Project Server in conjunction with a business application with XAF. The effect of the introduction was 17% reduction in construction time or 166 million rubles saving site costs for a year and a half.
FAMILY RESOURCES MANAGEMENT AND LIFE SATISFACTION OF ELDERLY
Authors: Sulityowati Asri , Krisnatuti Diah
Published: February 2019

Elderly especially widower and widow must have done family resources management
(FRM) in order to achieve satisfaction in life. This study was conducted to analyze the
influence of family resource management on life satisfaction of elderly widower and
widow. This study was using cross-sectional study with purposive for site selection in
Timbulharjo Village, Sewon Subdistrict, Bantul, Yogyakarta Province. Total of 60
samples were gathered with a combination of simple random sampling and snow-ball
techniques. The results of this study indicated atsocioeconomic status of the widower
was higher in terms of average age and duration of education rather than widows,
moreover the income of elderly widower greater than the widows. Non-food
expenditure, stress management, and time management had a positive effect on the
satisfaction of elderly life hence the more allocation on non-food expenditure, the better
of stress management and time management could improve life satisfaction of the
elderly. In addition, marital status associated and had a significant negative effect
towards life satisfaction which mean that life satisfaction of elderly widower higher than
the widow.
CA-M Application of Chicken Manure and Biofertilizer Ekstragen as the Efforts of the Development Okra (Abelmoschus esculentus) Plant Organically
Authors: Muliadi Muliadi
Published: February 2019

mungdsainsone@gmail.com

ABSTRAK

            Penelitian ini bertujuan untuk mengetahui dosis pupuk kandang ayam dan dosis pupuk hayati ekstragen yang tepat sebagai upaya pengembangan tanaman okra (Abelmoschus esculentus) secara organik. Percobaan dilaksanakan mulai Maret sampai dengan Juni 2018 di lahan pertanian desa Pijot Kecamatan Keruak Kabupaten Lombok Timur. Metode yang digunakan adalah metode ekperimental dengan percobaan di lapangan. Rancangan yang digunakan adalah rancangan acak kelompok dengan 3 ulangan. Faktor pertama adalah Faktor kedua adalah pupuk kandang ayam dengan 4 taraf dosis yaitu 0 kg/plot, 7,5 kg/plot, 9,5 kg/plot, 11,5 kg/plot. pupuk hayati ekstragen dengan 4 taraf dosis yaitu 0 ml/tanaman, 9,3 ml/tanaman, 13,8 ml.tanaman, 18,6 ml/tanaman. Terdapat 16 kombinasi perlakuan dan 48 petak percobaan. Data dianalisis menggunakan analisis sidik ragam, apabila berbeda nyata, maka dilanjutkan dengan uji BNJ pada taraf 5%. Hasil penelitian menunjukkan bahwa pupuk kandang ayam berpengaruh nyata terhadap pertumbuhan vegetatif terutama pada laju pertambahan diameter batang tanaman dan pertumbuhan generatif. Pupuk hayati ekstragen berpengaruh tidak nyata terhadap pertumbuhan vegetatif dan generatif tanaman. Disarankan untuk melakukan penelitian pada dosis pupuk kandang ayam untuk budidaya okra adalah 9,5 kg/plot atau sama dengan 25 ton/ha karena berbeda nyata dengan dosis 0 kg/plot, namun berbeda tidak nyata dengan dosis 7,5 kg/plot dan 11,5 kg/plot pada penelitian ini, sedangkan dosis pupuk hayati ekstragen disarankan melakukan penelitian lebih lanjut karena tidak adanya pengaruh signifikan terhadap pertumbuhan vegetatif dan generatif tanaman.

Kata kunci: Okra, pupuk hayati ekstragen, pupuk kandang ayam
Tax sanctions, tax amnesty program, and tax obligation placement towards compliance report on corporate taxpayers
Authors: Prena Gine Das , Kustina Ketut Tanti , Dewi I Gusti Ayu Agung Omika , Putra I Gede Cahyadi , Krisnanda Rama Adi
Published: February 2019

The level of taxpayer compliance was very low. It was due to the lack of the taxpayer’s knowledge in fulfilling tax obligations. The level of the taxpayer’s awareness has not reached the expected level. The study was intended to determine whether there were significant effects of taxation sanctions, tax amnesty program, and assets placement report on compliance with tax obligations of the corporate taxpayers conducted at the Official Service of Pratama Tax in East Denpasar. It was used, 293 respondents. The research method used was a descriptive method with survey technique through questionnaire distribution. Statistical testing used multiple linear regression analysis where the influence of variables was tested using the t-test. The research obtained that taxation sanctions, tax amnesty program, and assets placement report affect the compliance of tax obligations of corporate taxpayers with an influence of 78.6% was a positive direction, while the remaining 21.4% was explained by other factors not examined.
TOPICAL ISSUES OF FINANCING ELECTRONIC LEGAL PROCEEDINGS IN UKRAINE
Authors: Kovalenko Nataliia , Bernaziuk Ian
Published: February 2019

The aim of the article is to interrogate and reveal the current issues of financing electronic legal proceedings in Ukraine. The subject of the study is the financing of electronic legal proceedings in Ukraine. Methodology. The study is based on general scientific and special-scientific methods and techniques of scientific knowledge. The historical and legal method enabled to examine the current state of affairs in introducing the system of e-justice, to reveal the concept of e-Court. The comparative legal method enabled to compare the doctrinal approaches to the functioning of the ordinary system of courts and the system of e-justice. The system-structural method contributed to the consideration and identification of the most negative consequences of the delayed implementation of the e-justice system in Ukraine. The methods of grouping and classification were the basis for the author’s approach to the identification of possible sources of funding for the e-justice system. The technical legal method enabled to interrogate the state of affairs in electronic legal proceedings in Ukraine and highlight the problematic issues of the practical implementation of this institute, as well as emphasize the need to increase funding for the e-justice system in Ukraine. The results of the study enabled to distinguish problematic issues and ways of their solution in relation to the financing of the e-justice system in Ukraine. Practical implications. In the study, first, the key aspects of introducing the e-justice system in Ukraine are outlined; second, the problems of the practical implementation of the system of e-Courts in Ukraine are highlighted; third, the author’s perspective for possible ways of functioning of the e-Court system in Ukraine is substantiated. Relevance/originality. The original author’s approach to the current state of affairs in electronic legal proceedings in Ukraine and the practical problems of implementing this institute is the basis for developing the most promising areas for the improvement of domestic legislation in this sphere.
MODELS OF FINANCING OF HIGHER EDUCATION INSTITUTIONS IN FOREIGN COUNTRIES
Authors: Leshanych Lesia , Miahkykh Iryna , Shkoda Mariana
Published: February 2019

The aim of the article is to study the problems of reforming the system of financing higher education in conditions of compliance with world quality standards of education. Besides, another aim of the article is also to substantiate of the perspectives of their use in Ukraine, on the basis of analysis of the main foreign models of higher education institutions financing. The subject of the study is the financing model of institutions of higher education in foreign countries. Methodology. The research is based on a comparative analysis of funding systems for higher education institutions in Ukraine and in foreign countries. The advantages and disadvantages of different systems of the financial provision of higher education are determined based on the analysis of the peculiarities of financing higher education institutions in Germany, USA, UK, Sweden, Norway, and Australia and in some other countries. On the basis of a comparative legal research of certain provisions of Ukrainian legislation, the possibilities and limits of the application of positive foreign experience in this field are defined. The results of the study showed that the financing of higher education at the expense of state funds should be directed only to the needs of the state. And the state, in its turn, should provide graduates with jobs that will help reduce unemployment among them. Currently, there is a partial improvement of diversification of funding sources in Ukraine. We mean that the provision of the status of a non-profit organization will give the first impetus to the formation of contract relations between higher education institutions and private organizations and will improve their financial position. The implementation of the foreign experience will make financing more transparent and will give an opportunity to distribute it according to the quality criteria of providing educational services. Practical impact. Experience of the developed economies and the analysis of the existing condition of financing of educational institutions of Ukraine allow defining the priority directions of improvement of a system of financing of the higher education. As the budget of Ukraine is not able to compensate all needs for financial resources of higher educational institutions, it is necessary to encourage private investments into education, training, and high technologies more actively. Besides, conducting researches, the international consultations, modelling and discussion of the schematic diagram and funding mechanism for the higher education in Ukraine is also expedient. Correlation/originality. Conducting a comparative analysis of financing models of higher education institutions in Ukraine and foreign countries is the basis for developing the most promising directions for the development of domestic legislation in this field.
TRANSFORMATION OF METHODICAL MARKETING APPROACHES TO THE INVESTIGATION OF THE PROBLEM OF FARMING AGRICULTURAL ENTERPRISES IN THE GRAIN MARKET IN GLOBALIZATION CHALLENGES
Authors: Lyshenko Margarita , Ustik Tatiana , Thermosa Irina
Published: February 2019

The purpose of writing the article is to justify the methodological principles and recommendations for the functioning of agricultural enterprises-producers of grain in the target markets for its sale under the conditions of globalization challenges. The production and sale of grain traditionally remains the main focus of the specialization of domestic agricultural enterprises, the source of more than a significant share of their income, the formation and implementation of export potential of the agrarian sector of the national economy, the solution of a number of problematic issues of food security and ensuring the stable development of the subjects of the sphere of production of various sectoral belonging and orientation. At the same time, raising the economic efficiency of the main activities of agricultural enterprises remains a central problem, which in fact produces a complex, multi-faceted, and multi-level problem of the formation and functioning of mechanisms for the effective functioning of agricultural enterprises in the grain market. Research methodology. The theoretical and methodological basis of the research is the classical positions of economic theory, fundamental works, and scientific developments of domestic and foreign scientists on the effective functioning of agricultural enterprises in the grain market, the dialectic method of cognition, and the systematic approach to the study of social phenomena and processes that occur in the process of carrying out the main activity enterprises producing grain. In accordance with the goals and objectives of the article, such general scientific and special methods of economic research as monographic (in-depth study of the set tasks), abstract-logical (a theoretical generalization of the research results and formulation of conclusions and proposals) were used. Taken together, these methods form the methodological basis of the study. Results. After conducting the research, we decided that the study of the problem of the functioning of agricultural enterprises in the grain market is the study of methodological approaches to the evaluation of structural and dynamic trends of development and the state of the situation of target markets for the production of agricultural enterprises-producers of grain in the context of establishing systems supporting strategic and tactical and operational decisions in the production and commercial planes based on the system of integral indicators and individual indicators of the state of the targets. Practical use. The results of the research can be used at the state and regional levels of management in forecasting the change and the state of market equilibrium in the agrarian market of Ukraine and the conjuncture of the world and regional markets for agricultural products and food.
METHODOLOGICAL PROVISIONS ON THE PERFORMANCE EVALUATION OF AGRARIAN PRODUCERS AND THEIR COOPERATIVE ASSOCIATIONS IN THE PRODUCTION AND SUPPLY CHAIN
Authors: Nikishyna Oksana , Bondarenko Svitlana , Zerkina Oksana
Published: February 2019

The purpose of the article is to develop methodological provisions on performance evaluation of agrarian producers and their cooperative associations in production and supply chain on the basis of updated reproduction approach that is based on the use of net value added indicator. The research methodology is to conduct a critical analysis of existing scientific approaches to the assessment of value added; substantiate components of net value added; develop a structural scheme of methodological provisions in the duality of conceptual and methodological bases; substantiate a four-level system of estimating indicators using the net value added indicator; determine the possibilities and advantages of author’s methodological provisions. Results. The authors prove the expediency of using the net value added indicator to assess the efficiency of both production and supply chains, as well as producers and their cooperative formations that are non-profit organizations. The components of net value added, which include wages, profit, and specific expenses of business entities in terms of the parts of the production and supply chain, are substantiated. The authors proposed a structural scheme of methodological provisions that united the conceptual and methodological bases, defined the main principles of evaluation: objectivity and accuracy, systemacity and complexity, efficiency, purposefulness, the priority of economic interests of the state (macrolevel). A four-level system of indicators is developed for estimating volumes and dynamics of net value added, reproductive product profitability, the structure of net value added, the efficiency of material and labour resources use. Practical implications. Methodological provisions can be used by commodity producers and their associations to assess the efficiency of operation in the production and supply chain, justifying the feasibility of establishing a cooperative in the region. Also, the results of the analysis can be used by the state authorities during the definition of “gaps” in the chain and the justification of methods of selective regulation for its balanced development. Value/originality. Methodological provisions developed by the authors form the analytical foundation for making managerial decisions both at the micro level (producers, cooperatives) and meso and macro levels (regional and state authorities).
REALIZATION OF THE RIGHT OF REBELLION: FROM THE MANIFESTATION OF DEMOCRACY TO A CRIME AGAINST THE STATE
Authors: Orlov Yurii , Yashchenko Andrii , Hladkova Yevheniia
Published: February 2019

The objective of the article is to identify, describe, and explain the grounds and conditions for realizing the right of rebellion, delimitation of the relevant democratic procedures from anti-state crimes. The main results of the research are that we have established the liberal and democratic principles for the realization of the right of rebellion. It has been established that it can be realized only on the grounds of the extreme necessity in restoring the rule of law, that is, while having an exclusively criminal and preventive purpose. We have also discovered that both a democratic procedure of realizing the right of rebellion can be solely considered on condition of sufficient justification, proof of the long ineffectiveness of other means of influencing the criminalized apparatus of the state, in particular judicial ones. It has been substantiated that the essential condition for the realization of such a right is the critical level of nonconfidence to the personnel of the highest agencies of state power in the overwhelming majority of the population, as well as the actual impossibility to apply (implement) the statutory forms of influence on their personnel. It is mandatory to consider the requirement of ensuring national security on the basis of a scientifically grounded criminological forecast of the deployment of mass resistance, taking into account the probable reaction to it by the subjects of international law. Thus, the realization of the right of rebellion should be non-violent. In all other cases, there is a criminal seizure of state power. The applied value of the research is the fact that due to the developed system of grounds and conditions for realizing the right of rebellion, the latter, as it is, may be delimitated from political criminal practices aimed at dismantlement of the Constitutional statehood, the seizure of state power. The results of the research may also be taken into account by political actors, as well as law enforcement agencies, courts while criminological substantiation, prediction of mass resistance measures, and legal assessment of such actions. Value/originality. The authors of the work have improved the criminological vision of the movement of mass resistance, which can take place both in the form of the realization of the natural right of rebellion and in the form of anti-state crimes. The use of these developments can be useful in the retrospective legal assessment of the situation of mass protests, forms, means, and consequences of responding to them by the authorities, preventing abuse of the right of rebellion and related crimes.
LEGAL DESCRIPTION OF THE FACTORING CONTRACT IN ROMANIA
Authors: Pylypenko Svitlana , Udovenko Yuliia , Cherneha Vitalii
Published: February 2019

In light of the fact that capital is a major factor in production, the development of entrepreneurial activity becomes impossible without considering the financial market and the resources provided to its subjects. Regardless of the degree of development, any entrepreneurial activity is engaged in direct contact with financial markets, in particular through institutions that act as intermediaries in raising money and services. The development of a solid basis for doing business requires understanding the rules of functioning of the financial system and its mechanisms. Considering the current economic situation, as well as the procedure for granting loans by banks, which is gradually becoming more complicated, while the national and international markets require capital movement, factoring becomes the most accessible instrument and only source of financing, with which the latter increases concurrently with sales. Therefore, the aim of this article is to study the legal nature of the factoring contract in Romania: to identify its regulation object, functions, types, legal features, and other specificities to introduce the positive experience of foreign colleagues to the legislation of Ukraine. Methodology. It is proved that the current legislation concerning the issue of factoring in Ukraine should be improved because in our country the factoring market is still not very common in spite of its rapid development in the world. Moreover, there are no thorough studies on factoring in general and a factoring agreement in particular; some issues on this topic have been considered only in scientific articles. Therefore, the authors refer to the legislation of Romania to determine those features of legal regulation, which have contributed to the rapid and effective development of this institution in this country, and to make appropriate proposals for improving domestic legislation with the use of positive foreign experience. Results. The article suggests a general description of the factoring contract in Romania: the concept of this agreement is revealed; the object of its regulation, as well as implementation of the factoring contract, is determined; its functions and features are described; the parties to the agreement and their legal status are determined. The specificities that have contributed to the rapid enlargement of factoring in Romania are given particular consideration. Practical implication. The factoring agreement as an operating instrument for credit institutions is especially important due to its constant practical applicability that enables to choose the optimal commercial activity both at the national and international levels. Relevance/originality. In Ukraine, given the need for further development of entrepreneurial activity, the issue of increasing total factoring operations is important. The implementation of positive international experience on this issue in domestic legislation is essential for this stage.