bluuebunny/crossref_metadata_2025 huggingface dataset:
Dynamic assessment of intraperitoneal aerosol chemotherapy under pressure impact on peritoneal carcinomatosis in ovarian cancer (immediate results)
Authors: Dzasokhov A. S. , Kostin A. A. , Astashov V. L. , Andreev M. A. , Turiev A. V. , Uskov A. D.
Published: March 2023

Purpose of the study. Dynamic assessment of the direct impact of pressurized intraperitoneal aerosol chemotherapy (PIPAC) on peritoneal carcinomatosis in ovarian cancer.

Patients and methods. The study involved 164 people with visually detectable and morphologically verified ovarian cancer with peritoneal carcinomatosis of the peritoneum (IIIb-IIIc stages of ovarian cancer). All patients underwent combined treatment of ovarian cancer, which included primary cytoreduction and 6 courses of сhemotherapy according to the TC scheme. In the main group, the standard treatment was supplemented with 3 sessions of PIPAC. Statistical processing was carried out by analyzing the exact criterion of the Wilcoxon-Mann-Whitney sums, the distribution of patients in groups by age and peritoneal lesion was estimated. It was found that the distribution of the analyzed parameters was random. The distribution in the groups by stages of the disease was homogeneous, which is justified by the use of the Barnard criterion. The dynamics of the parameters of the study was evaluated by the methods of basic statistics. Used software packages: MedCals, Statistica.

Results. The results obtained demonstrate a distinct positive dynamics in the group of patients receiving PIPAC in addition to standard treatment of newly diagnosed ovarian cancer: a significant decrease in the peritoneal cancer index, therapeutic pathomorphosis in peritoneal samples during treatment, reduction of ascites.

Conclusion. The team of authors managed to establish that PIPAC simultaneously with standard combined treatment for newly diagnosed ovarian cancer with peritoneal carcinomatosis makes it possible to achieve a dynamic regression effect of peritoneal carcinomatosis of the peritoneum, morphological regression of carcinomatosis and complete resorption of ascites in the vast majority of treated patients. The revealed therapeutic effect was prolonged and persistent with an objective assessment 6 months after the end of treatment.
Modern approaches to glioblastoma therapy
Authors: Kuznetsova N. S. , Gurova S. V. , Goncharova A. S. , Zaikina E. V. , Gusareva M. A. , Zinkovich M. S.
Published: March 2023

Glioblastoma (GBM) is the most malignant and the most common primary tumor of the central nervous system. During the last several years GBM has been classified and managed according to the World Health Organization (WHO) criteria which subdivide it into primary and secondary GBM. As it is suggested, GBM originates from glial cells and has a diffuse growth pattern, but its etiology and pathophysiology are poorly investigated up to date. Its rapid progression and anatomical location in the brain often limits the effectiveness of therapeutic interventions. Despite all scientific and technological advances, GBM remains an incurable disease with a median survival of approximately 18 months. Standard treatment options involving maximal safe resection of the tumor followed with radiotherapy and chemotherapy do not provide satisfactory Results.

Better understanding of the molecular pathology of GBM and its associated signaling pathways has opened up possibilities for new treatments for newly diagnosed and relapsing tumors. A multitargeted therapeutic approach using compounds capable of inhibiting more than one specific molecular target is a promising alternative to conventional therapies.

Currently, specialists study such innovative treatment options as small molecule inhibitors aimed at signaling pathway disruptions, immunotherapy, including checkpoint inhibitors, oncolytic vaccines, CAR T-cell therapy, and drug delivery systems. In terms of an innovative approach, the elaboration of targeted drug delivery systems is of particular interest, since this strategy looks the most promising due to its ability to increase the bioavailability and effectiveness of both standard and newly tested agents. This review discusses results of preclinical and clinical studies of innovative therapeutic approaches, their advantages and disadvantages. An interdisciplinary approach is expected to be able to combine the results of cutting-edge research in this area and to provide novel promising therapeutic strategies for patients with GBM.
Molecular features of malignant gastric tumors
Authors: Gevorkyan Yu. A. , Dashkov A. V. , Soldatkina N. V. , Kolesnikov V. E. , Timoshkina N. N. , Krutilin D. S. , Bondarenko О. К.
Published: March 2023

Gastric cancer is one of the most widespread cancers and makes a significant contribution to the global mortality rate from malignant neoplasms. The late onset of clinical symptoms is the main reason why the disease is often diagnosed at an advanced stage, and this limits the available therapeutic approaches. Despite the fact, that extensive studies have been carried out to identify the mechanisms and markers of the development and progression of the disease, their results are currently not fully included in clinical practice. As a consequence, only marginal improvement in long-term survival has been achieved and patient prognosis remains poor. Understanding the molecular genetic features of gastric malignant tumors can provide insight into their pathogenesis, help identify new biomarkers for prognosis and diagnosis, and identify new therapeutic targets. In recent decades, advances in high throughput sequencing technologies have improved understanding of the molecular genetic aspects of gastric cancer. This review considers molecular level changes, including information on tumor suppressor genes, oncogenes, cell cycle and apoptosis regulators, cell adhesion molecules, loss of heterozygosity, micro-satellite instability and epigenetic aberrations (change in methylation level and modification of histones). The review is also devoted to the molecular aspects of pathogenesis – changes in the signaling pathways involved in the gastric cancer development; the classification of sporadic and hereditary gastric cancer at the molecular genetic level is considered. The characteristics and classification of GC presented in this review at the genetic and epigenetic levels confirms that this disease is heterogeneous. These data can be used both to develop and test potential markers and new targeted therapeutic approaches.
Optimal management of long-term air leakage after lung resections for cancer
Authors: Iozefi K. D. , Kharagezov D. A. , Lazutin Yu. N. , Stateshny O. N. , Milakin A. G. , Leyman I. A. , Ayrapetova T. G. , Vitkovskaya V. N. , Gappoeva M. A. , Mirzoyan E. A. , Khomidov M. A. , Shevchenko A. N. , Dimitriadi S. N.
Published: March 2023

Lung resection is the main diagnostic and therapeutic surgical intervention in terms of lung cancer management. Air leak through pleural drains often occurs after lung resections due to damage to the pulmonary parenchyma. Therefore, proper drainage of the pleural cavity is very important for the successful outcome of the operation. The installation of a single pleural drainage after anatomical resection, the refusal to use vacuum aspiration and the earliest possible removal of drains contribute to the rapid activation of patients in the postoperative period. Prolonged air leakage (PAL) after lung resection, on average, develops in 15 % of lung cancer patients, remaining one of the most common complications adversely affecting the rehabilitation of patients and leading to delayed discharge from the hospital. The incidence of empyema with prolonged air leakage is 10.4 % with air discharge for more than 7 days compared to 1 % with air leaks less than or equal to 7 days. PAL requires prolonged drainage of the pleural cavity, which increases postoperative pain, causing shallow breathing, difficulty coughing leads to an increased risk of pneumonia, decreased mobility is accompanied by a high risk of thromboembolic complications. In addition, the treatment of complications is associated with the need to perform additional invasive interventions such as chemical or mechanical pleurodesis. Prolonged air leakage is associated with an increase in hospital mortality. Patients with an air leak have a 3.4 times greater risk of death than patients without it. Active tactics in relation to PAL include preoperative prediction of a high risk of complications, intraoperative measures to prevent air leak from the lung parenchyma and postoperative treatment to reduce the duration of PAL. The urgency of the problem is due to the fact that prolonged air leakage in patients with lung cancer after organ-preserving operations is associated with an increased risk of infectious complications due to the need for prolonged drainage of the pleural cavity. In this review, the main attention is paid to two components of postoperative management of PAL: diagnosis with an accurate assessment of the intensity of air leak and treatment of alveolar-pleural fistulas.
CHANGING CITY AND EMOTIONS: SURAT CITY IN GUJARATI GHAZALS
Authors: Gajjar Kashyap
Published: March 2023

Emotions are the most valuable treasure of humankind. It depends on the level of attachment to another person or object, as well as the level of experience. Emotions vary in response to changes in experiences and situations. The study of emotional changes is important, and it becomes much more fascinating when the emotional bonding is between a place or a city rather than a person. Every city dweller has a strong emotional relationship with the place where they were born or grew up, and they express their feelings in a variety of ways. Poets convey their feelings of love or disappointment for the city in a variety of poetic genres. The city eventually undergoes various changes as a result of modernization, which alters the poet’s experience including the poet's surroundings. The city undergoes various changes as a result of the powerful impact of modernism, which alters the poet’s experience as well as the changing emotions linked with it. The study focuses on the concept of place attachment and changes in poets’ emotions for the city, using Gujarati ghazals on Surat as an example to show how earlier the concrete was emotions, but now emotions have become concrete.
THE CONCEPT OF NIRVANA AND SAMSARA IN BUDDHISM AND ITS RELEVANCE IN THE PRESENT-DAY WORLD
Authors: Navneet Rekha , Singh Suyasha
Published: March 2023

In this paper, we shall focus on the Buddhist approach of living responsibly engaged with the world and yet, mindfully liberating oneself from selfish dispositions, consumeristic tendencies and parochial biases. We have focussed our attention to the point of understanding nirvana (the state of liberation) as the stage of transformation in a person to mindfully and compassionately engage with the Samsara (the lived experiences of the world). The focal argument in the paper is that Nirvana is present in every social, economic, cultural and political transactions of life. The Consciousness or awareness or prajña is at the grassroots of every sensation and thought we witness which is in actuality, “I” that is not constrained to any permanent individual/ego identity. Therefore, humans are agents who think, will and act, and can transform their lived situation with righteous karma by following virtues of compassion and friendliness and thinking and contemplating with a steadfast mindfulness. Buddhist precepts that guide a righteous living are rooted primarily in their doctrines of anatta and nirvana. These concepts have been delineated alongside their theory of causation (Pratityasamutpada) that explains reasons leading to suffering, and this theory is among one of the ‘four noble truths’ besides Nirvana and ethical noble path. The paper affirms that Buddhist concepts can be used as models of wisdom treatises that foster leading a life of humanistic and ethical spiritualism much needed to counter challenges fostered by the present-day world stuck with technological invasion replacing human endeavour, contagions causing pandemic and the greed to control the geo-political dynamics by some nations.
IMPEDIMENTS TO INDIA’S UNSC BID
Authors: Jeremy Kangdhi
Published: March 2023

Major political parties in India either implicitly or explicitly in their election manifestos talks about getting India its rightful place among the comity of nations, a seat at the high table in global affairs and international institutions. This aspiration is reminiscent of India’s great and glorious civilizational past, the birth place of many religions, rulers, scientists and architects, the land of Buddha, Ashoka, Kautilya, Akbar, Arayabatha, Brahmagupta and so on.

Since its independence in 1947 and decades thereof, with the opening stint made by Nehru spearheading the Non-Aligned movement with other world leaders. India is rising economically, politically and socially, it is now beginning to seize this era of greatness whose time has come. Among its ambitions on world stage, to be a member of the UN Security Council tops their agenda. Given its growing importance, United States, United Kingdom, France and Russia, four of the five current permanent members have pledge vocal support for India’s candidacy. In this light, it is worth recalling why India is considered strong and growing today. ‘Unity in Diversity’ seems to be the quintessence in India’s case, through which strength emanates and uplifts the nation. If diversity is counted as India’s strength, then propagandas and majoritarian goals of imposing a bland uniformity, would produce neither unity nor strength; on the contrary it has the potential to blow up the fabric of a nation, and thereby render India’s UNSC bid futile and meaningless.
EMBRACING THE DEATH: EXPLORING POSITIVE PSYCHOLOGY IN LOUISE GLUCK’S A VILLAGE LIFE
Authors: Dhivya A . , Kishore S. Henry
Published: March 2023

Death, as an inevitable event, occurs in the life of every living creature which plays a vital role as equivalent to the event of birth. According to the situation, death differs for each person weighing either as a boon or burden in their life. While few neglect it out of fear, escaping from reality is not possible at every time, instead developing the level of acceptance is practicality and it could also enhance the mental health of a person. Unlike other authors portraying death as a bleak theme, this paper argues that Gluck in her poems— views death as the theme of rebirth in an optimistic view and through reinforcing hope she focuses on lightness from the dark experiences. This paper emphasizes on positive psychology theory that helps to kindle the positive emotions and strengthen the human mind during the times of depression. Ostensibly there is no place for any alterations in this event of death, but even so embracing death throws the rays of optimistic energy that provokes the inner confidence to overcome the hardships.
CHALLENGES OF ONLINE TEACHING-LEARNING IN HIGHER EDUCATION SECTOR AMID COVID-19: A STUDY THROUGH THE LENS OF STUDENTS AND TEACHERS OF WEST BENGAL
Authors: Islam Md. Nijairul , Mondal Ajit
Published: March 2023

Since middle of March, 2020, all the academic institutions from KG to PG level in India have been shut down to prevent spread of infection of corona virus. As a corollary, both teachers and students have been going through a paradigm shift in platform of teaching-learning, i.e., from offline to online, from the old, chalk and talk model to one driven by technology. The central and the state governments have come forward with a cluster of e-learning initiatives during this juncture. In spite of creating governmental and institutional supports, substantial researches confirm that students and teachers have been facing wide-ranging challenges associated with online teaching-learning. In the near future, digital education is likely to be incorporated side by side face-to-face education. Against this backdrop, this paper intends to peep into the degree of preparedness in West Bengal and in India nationally towards online teaching-learning in higher education sector. It primarily aims to explore the daunting challenges of online education in higher education sector (UG and PG level) particularly in the Indian state of West Bengal through the lens of students and teachers with an objective of proposing an evidence-based set of future roadmaps.
EDUCATION AND SOCIETY: ROLE OF SCHOOLS IN INFLUENCING THE MECHANISMS OF SOCIETAL STRUCTURE
Authors: Mazumdar Suman
Published: March 2023

The concept of education is both normative and constructive. The educational curriculum is planned and structured so that it examines social, political, economic, and educational processes and issues while also looking for answers to address societal requirements. The school, as a social sub-system, aids in educating people about social conventions, practices, norms, traditions, values, and beliefs while also helping them acquire the social skills necessary to form relationships with other people in the community. Students are able to analyse, assess, and bring about the required changes in society when they have the proper information and a solid understanding of social processes and structure. The article significantly discusses about the idea of education in relation to society and the mechanisms encompassing the interaction between social structures and educational institutions.
Development of Village Administration Data E-Monography Application
Authors: Megawati Suci , Prabawati Indah , Tauran Tauran , Eprilianto Deby Febriyan , Al Amin M. Noer Falaq
Published: March 2023

Utilization and processing of basic village data by the Kedungluk Village Government, Candi District, Sidoarjo Regency, through e-monograph is an effort by the village government to carry out a transformation process to develop an information culture. This study aims to determine the development and design of an application-based information system prototype (village monograph) that provides information and potential as well as village profiles, and provides convenience for village monograph data managers and users. In addition to providing benefits to the village government through the e-monograph application prototype, this research is also expected to contribute to learning in the State Administration Study Program by presenting a learning model that can provide opportunities for students to learn directly (become a laboratory) related to the use of information technology in designing and managing public sector organizations in accordance with the learning outcomes of the fourth study program. The research method used is the Research & Development (R&D) method where one of the models suitable for this research is the SDLC (Software Development Life Cycle) model and specifically the Waterfall model which consists of six stages of software development namely requirements, design, implementation, testing, deployment and maintenance. The output of this research is software or software.
Problems with Complete Systematic Land Registration Regulations Perspective of Legal Certainty
Authors: Sudrajat Cucu , Suriaatmadja Toto Tohir , Jamilah Lina
Published: March 2023

One of the government's endeavors to promote legal clarity and maintain communal land rights is to register all land in Indonesia. The Ministry of Agrarian Affairs and Spatial Planning/National Land Agency is in charge of a statewide program called Complete Systematic Land Registration, which aims to speed up the land registration process. In accordance with the directive issued by the Minister of Agriculture and Spatial Planning/National Land Agency Director. A number of problems prevent the implementation of Complete Systematic Land Registration, including inconsistencies in government regulations, the Minister of Agrarian Affairs and Spatial Planning's regulations, and the Law on Regional Taxes and Regional Retributions. Legitimacy Theory, Legal Validity Theory, and Legal Certainty Theory all stipulate that statutory regulations may not conflict with other regulations in order to provide certainty; these theories should be followed if the government is serious about achieving the goal of Complete Systematic Land Registration. Legislation provides safeguards for those with title to land, free of normative conflicts and the potential for multiple interpretations at the administrative and judicial levels. Both the normative legal approach and the synchronization legal approach will be included into the analysis of the qualitative data used in this study.
ANTI-OXIDANTS AND LUNG CANCER
Authors: Abid Shariq Anwar
Published: March 2023

Antioxidants are showing assoiation with development and progression of malignancy.
CORRELATION OF COVID-19 SEVERITY with HEMATOLOGICAL, BIOCHEMICAL, COAGULA-TION AND INFLAMMATORY MARKERS- A CROSS-SECTIONAL STUDY
Authors: Ullah Anwar , Khan Muddasir , Afridi Sahib Gul , Shah Khalid
Published: March 2023

Coronaviruses cause exceptionally contagious infections and at present they pose a major concern of public health worldwide. This study was conducted to evaluate the severity of Corona Virus (COVID)-19 through hematological, biochemical, coagulation and inflammatory markers. This was a cross-sectional study including 200 COVID-19 patients (97 with non-severe and 103 with severe diseases) admitted to Hayatabad Medical Complex, Peshawar, Pakistan from December 2020 to June 2021. The patients were initially screened through Real-time PCR and positive confirmed patients were further evaluated for serum ferritin, C-reactive protein (CRP), lactate dehydrogenase (LDH), D-dimer, and complete blood count (CBC) by using the standard protocols. Among the 200 COVID-19 positive patients, male positive patients were predominant (n= 138, 69%), and the most prevalent age group was 41 to 60 years (i.e., 49%). CRP was found to be most frequently deranged (95%) followed by D-dimer and LDH levels in 92% of patients. The abnormal levels of neutrophils, lymphocytes, ferritin, and hemoglobin were recorded as 83%, 82%, 79%, and 20%, respectively. All studied inflammatory markers significantly (p <0.005) correlated with the severity of COVID-19 patients.
COMPARISON BETWEEN EFFICACY OF TYGECYCLINE AND MINOCYCLINE IN MULTI DRUG RESISTANT ACINETOBACTER BAUMANII ISOLATED FROM RESPIRATORY TRACT INFECTIONS
Authors: Khan Fouzia , Fatima Ambreen , Gohar Hareem , Sajjad Mehwish , Iqbal Sahar
Published: March 2023

Corona Virus (COVID)- 19 is a pathogenic viral infection that presents as a new worldwide public health crisis. This review article aims at recapitulating waves of COVID-19, vaccination programs, treatment options, and the current scenario of COVID-19 in Pakistan. All available literature on PubMed, Scopus databases and science direct and Google scholar relating to COVID-19 published between 2019 to January 2022 was reviewed. The first wave of COVID-19 presented as severe acute respiratory syndrome. The second wave had a modest intensity, affecting only Sindh's southern province, and peaked in mid-December 2020. The third wave, which primarily disturbed the regions of Khyber Pakhtunkhwa and Punjab, peaked in the late April 2021, when a new strain of SARS-CoV-2 was discovered in over 64 countries, including Pakistan, as of January 27, 2021. Fourth wave qualifying measures was forced in May, after which cases balanced out and most of the mortality was reported in Punjab, followed by Sindh. The 5th wave with a positive ratio in Karachi had the increasing trend from 2% to 6%. In clinical trials, treatment with a combination of Azithromycin and Chloroquine shown efficacy against COVID-19. The Tocilizumab was used to treat COVID-19–related symptoms. Vaccination appeared to be vital to control the COVID-19 disease outbreak with seven licensed vaccines.  Currently 72% Pakistani population is either vaccinated or have been infected at least once.
VENOUS THROMBOEMBOLISM AND ITS OUTCOME IN PEDIATRIC PATIENTS AT A TER-TIARY CARE HOSPITAL OF KARACHI
Authors: Rimsha Shahid  , Misbah Anjum  , Safia Bibi  , Shazia Soomro  , Hifza Aiman  , Shahzadi Dilawar
Published: March 2023

Venous thromboembolism (VTE) was once considered a rare finding in pediatric population but it has been increasing with recent advances in medical care and technology to diagnose it. This study was conducted to determine the clinical presentation, associated factors and outcome of VTE in hospitalized children in a tertiary care children hospital of Karachi. This descriptive cross sectional study was conducted at National Institute of Child Health, Karachi from December 2020 to January 2022. All patients hospitalized with VTE or who were diagnosed to have DVT while at hospital were included in study. Demographic characteristics, clinical presentation, medical history and laboratory workup was recorded in a semi-structured proforma. Patients were managed by treating physicians as per hospital protocol. Treatment details were recorded along with outcome. A Total of 36 children were diagnosed with VTE. Nine (25%) patients were admitted with clinical features suggestive of DVT while remaining 27 (75%) developed DVT during hospital stay. Median hospital stay of those who developed DVT at hospital was 15 days (IQR 10-30days). Infectious etiology (n=21, 58.3%) was the most common admitting diagnosis followed by central nervous system disorders (n=4, 11.1%). Common clinical features among VTE children were fever, seizures and edema of limbs. Prolonged hospital stay with immobilization and central venous catheterization particularly due to infectious etiology are common factors among children who develop VTE and such patients need to be considered for VTE prophylaxis and treatment.
A SIMULTANEOUS PATH PLANNING AND POSITIONING BASED ON ARTIFICIAL DISTRIBUTION OF LANDMARKS IN A GNSS DENIED ENVIRONMENT
Authors: Elahian Samaneh , Amiri Atashgah Mohammad-Ali , Tarverdizadeh Bahram
Published: March 2023

In recent years, exploration operations by autonomous robots are expanding into unknown environments on Earth, under the sea, or even on other planets. This paper proposes the idea of Concurrent Path Planning and Positioning (CPPAP) using artificially distributed landmarks, while no GNSS signal is available. The method encompasses an observability-based direction search algorithm for path planning in parallel with Simultaneous Localization and Mapping (SLAM) for localization. Most of the path planning methods utilize offline algorithms; however, the proposed method determines the robot’s direction of motion in real-time, concurrently with the positioning tasks by the inclusion of the system observability, related to the features’ distribution. Same as in all feature-based SLAMs, features play an important role in determination of the most observable direction, and hence the direction of the robot’s motion. Moreover, the effectiveness of the distribution of the features and their pattern in the proposed method is investigated. To evaluate the efficiency and accuracy of the CPPAP, outcomes are compared with an existing random SLAM.
HOUSING PREFERENCE STRUCTURES IN EAST ASIA: AN EMPIRICAL STUDY AND NON-PARADIGMATIC SHIFTS BETWEEN NEARBY METROPOLES
Authors: Zhuang Zheng-Yun , Fu Chen-Hua
Published: March 2023

A systematic research flow was applied to the Southern Metropolis in Taiwan not only to recount residents’ considerations in this cultural area but also to compare them with those of other metropolitans on the island in relation to general housing concerns. The constructs and factors in housing decision-making were justified using the literature, confirmed with experts in the field, and organised as a decision hierarchy that formed the foundation of a survey. The investigation combined the analytic hierarchy process and Student’s t-test, both of which are credible methods, to facilitate a grounded process for mind mining. The importance of constructs/factors were thus assessed on a numerical basis, and a set of unforeseen insights were explored for the different parties of interest (e.g., buyers, construction companies, agents, asset managers, etc.). Opinion gaps between different sample groups were identified. This set of empirical knowledge filled the gap in the literature. It is noteworthy that among the constructs in the region studied, (housing) ‘conditions’ dominated ‘price’, while ‘location and transport’ was the least important. A ‘non-paradigmatic shift’ in people’s total housing preference structure, which changed gradually with decreasing population density and increasing plain geography from the north to the south between nearby metropoles, was observed, despite the niche but commensurable cultural norm in East Asia being the overall scenario of the island. Some existing claims about the housing preferences in this area were also either supported or rebutted by the quantitative evidence(s).
Augustus Hamilton’s fossil collection at the Museum of New Zealand Te Papa Tongarewa
Authors: Ioane-Warren Melanie , Salvador Rodrigo B. , Rogers Karyne M. , Tennyson Alan J. D.
Published: March 2023

Augustus Hamilton (1853–1913) was a New Zealand ethnologist and naturalist who amassed a significant collection of fossils, mostly of birds, during his career. Today, those fossils are housed in the Museum of New Zealand Te Papa Tongarewa (NMNZ). While some fossils have been catalogued and integrated into the collection of the NMNZ, a large part remained unsorted and uncatalogued. The present study brings an integrated view of Hamilton’s collection at the NMNZ, highlighting the most significant fossils. In total, there are 3692 specimen lots collected by Hamilton in the NMNZ representing a large sample of taxa and a wide range of locations around Aotearoa New Zealand. Most fossils are of Holocene age and belong to birds. The collection includes type specimens, circa 250 specimen lots belonging to extinct species, and specimens belonging to otherwise poorly represented species in natural history collections. We hope that our study makes Hamilton’s fossils visible and more readily available for future research.
Seven new “cryptic” species of Discodorididae (Mollusca, Gastropoda, Nudibranchia) from New Caledonia
Authors: Innabi Julie , Stout Carla C. , Valdés Ángel
Published: March 2023

The study of a well-preserved collection of discodorid nudibranchs collected in Koumac, New Caledonia, revealed the presence of seven species new to science belonging to the genera Atagema, Jorunna, Rostanga, and Sclerodoris, although some of the generic assignments are tentative as the phylogeny of Discodorididae remains unresolved. Moreover, a poorly known species of Atagema originally described from New Caledonia is re-described and the presence of Sclerodoris tuberculata in New Caledonia is confirmed with molecular data. All the species described herein are highly cryptic on their food source and in the context of the present study the term “cryptic” is used to denote such species. This paper highlights the importance of comprehensive collecting efforts to identify and document well-camouflaged taxa.
International Postgraduate Study in the United Kingdom: An Exploration of Nursing Students
Authors: Monaghan Catherine , Gormley Kevin
Published: March 2023

Background:

This study explored the experiences of international postgraduate nursing students from the Gulf Cooperation Council region as they transitioned from home to a university in the United Kingdom and then again as they reintegrated to work and life at home after completing their studies.

Method:

This research was grounded in Schlossberg's transition theory. A two-phased qualitative approach was followed, and semistructured interviews were conducted.

Results:

Analysis of qualitative data revealed the following themes: the presence of social integration, retransition, and readjustment.

Conclusion:

International students faced challenges as they adapted socially and academically to living in another country and also on their return home. The mechanisms students use to negotiate and make sense of the transition process suggest a need for universities to consider increasing preparation and orientation of students, supporting host and international student friendships, and ensuring students are equipped to reintegrate to their careers and cultures on their return home.

[
J Nurs Educ
. 2023;62(3):125–132.]
Integrating the Social Determinants of Health Into Prelicensure Nursing Pharmacology
Authors: Mueller Kenneth , Balthazar Monique S. , Hamilton Jill B. , Kimble Laura P.
Published: March 2023

Background:

Nursing organizations have called for the incorporation of social determinants of health (SDOH) throughout nursing school curricula. Guidance is needed regarding best practices to integrate SDOH into pharmacology courses in prelicensure nursing programs.

Method:

Using Emory University's School of Nursing SDOH framework to guide curriculum innovation, pharmacology faculty identified three pharmacology-centric SDOH topics: race-based medicine and pharmacogenomics, pharmacy deserts, and lack of diversity in clinical trials. These three SDOH topics were incorporated into preestablished pharmacology content.

Results:

Faculty integrated SDOH into pharmacology courses with heavy science content, and students were receptive to open discussion of SDOH topics.

Conclusion:

The integration of SDOH into a prelicensure nursing pharmacology course across multiple cohorts of students was feasible, and student feedback was positive. Faculty faced several challenges, including time constraints. Additional and ongoing training is needed to support the integration of SDOH into nursing curricula.

[
J Nurs Educ
. 2023;62(3):175–179.]
Multiple attribute decision-making based on Fermatean fuzzy number
Authors: Fahmi Aliya , Amin Fazli , M Eldin Sayed , Shutaywi Meshal , Deebani Wejdan , Al Sulaie Saleh
Published: March 2023

Multiple attribute decision-making concerns with production significant in our everyday life. To resolve the problems that decision makers might feel uncertain to choose the suitable assessment values among several conceivable ideals in the procedure. Fuzzy model, and its extensions are extensively applied to MADM problems. In this study, we proposed an innovative Schweizer-Sklar t-norm and t-conorm operation of FFNs, Fermatean fuzzy Schweizer-Sklar operators. They were used as a framework for the development of an MCDM method, which was illustrated by an example to demonstrate its effectiveness and applicability. Finally, a complete limitation study, rational examination, and comparative analysis of the presented approaches has been exhibited, we originate that our technique is superior in offering DMs a better decision-making choice and reducing the restrictions on stating individual partialities.
From industrial district to industrial symbiosis: An opportunity. The case of the Ponte Rosso industrial area, Italy
Authors: Džajić Uršič Erika , Jelen Igor
Published: March 2023

The article highlights the importance of industrial symbiosis in the industrial ecology literature, which refers to geographically close relationships between companies in which networks and geographic proximity play a vital role. Industrial symbiosis traditionally deals with different industries in a collective approach to economic and environmental management. The research was carried out in the northeast of Italy in the autonomous region of Friuli Venezia Giulia, close to the Slovenian border. The Ponte Rosso was used as a case study. The empirical analysis served to highlight some critical aspects of the environmental, geographic-economic, and social factors that could hinder the development of industrial symbiosis in this region
Socio-demographic analysis of border regions of Bosnia and Herzegovina
Authors: Avdić Aida , Avdić Boris , Zupanc Ivan
Published: March 2023

This paper analyses the statistical parameters that give a comprehensive overview of the socio-demographic state of the border areas of Bosnia and Herzegovina, and it represents a novel attempt to examine the disparity and relationships between central and peripheral parts of national territory. The methodology is based on examining the differences between border and non-border municipalities/cities according to four groups of indicators, to obtain four indices: depopulation, natural change, ageing and education. Statistically significant differences were found primarily in the context of population age structure, and it can be concluded that the ageing process has affected bordering regions more than the rest of the country.
OLMs Development to Improve Students’ Ability to Produce Learning Media
Authors: Safiah Intan , Yunus Muhammad , Ahadin  , Mislinawati  , Abdar Yusrijal
Published: March 2023

This study aims to develop e-learning-based Online Learning Modules (OLMs) suitable for higher education levels, especially for education students. The OLM development combines project learning models with LMS-based e-learning. An OLM can be an innovative learning approach that can assist teachers in delivering online learning during the pandemic. This study employed a research and development approach using an ADDIE model. Based on expert validation, the average score of all indicators fell into a very good category. The result implies that the developed OLMs were feasible to be implemented in a learning setting. After implementation, the students’ perceptions of the modules were also very good. Meanwhile, the study demonstrates that 34% of education students have an excellent ability to produce learning media, 60% have a very good ability, and 6% have good ability. Thus, it is concluded that OLMs could improve the ability of education students to produce learning media.
Comprehensive Test and Evaluation Path of College Teachers' Professional Development Based on a Cloud Education Big Data Platform
Authors: Wang Jinyu
Published: March 2023

Teachers serve as carriers who shoulder the important task of improving the quality of education, and their professional level affects the quality of vocational and technical personnel training. At present, the professional growth of teachers in vocational colleges has attracted more and more attention from the society. This article studies the comprehensive test and evaluation path of college teachers' professional development based on cloud education big data platform. This article constructs a "supply-demand relationship" model between cloud education big data platform and college teachers' professional development, and expounds the comprehensive test and evaluation strategy of college teachers' professional development based on cloud education big data platform. This article constructs a comprehensive measure index system of influencing factors of college teachers' professional development, and weights the evaluation indexes based on AHM attribute hierarchy model. By optimizing the super-efficiency SBM model, it proposes a comprehensive evaluation method considering the temporal and spatial features of college teachers' professional development level, which is suitable for different professional teachers' professional development features. The experimental results verify the effectiveness of the evaluation index system and evaluation model.
Digital Tool for Film Promotion Through the Use of Augmented Reality
Authors: Beltozar-Clemente Saul , Sierra-Liñan Fernando , Pucuhuayla-Revatta Félix , Zapata-Paulini Joselyn , Cabanillas-Carbonell Michael
Published: March 2023

After the isolation caused by the pandemic, the entertainment sector has been forced to change the way it markets its products and services, and users have been adapting to the change. Companies dedicated to the film industry have had to bet on digital marketing to attract customers through the promotion and advertising of movies, thus attracting a larger audience to their theaters. The objective of this research article is to provide added value and innovation to the advertising promotions of movies in the premiere, through the development of a mobile application based on augmented reality to improve customers’ shopping experience. For which the Agile Mobile-D Methodology was used for the development of the application and the results were studied using 5 indicators: Time to choose a movie, where an improvement of 38.26% was obtained compared to the Pre-Test; regarding the indicator time to acquire information about the movie, an improvement of 81.33% was obtained. 33%; concerning the third indicator, time to initiate the purchase, an improvement of 88% was obtained; concerning the fourth indicator, time to obtain a reminder, an improvement of 83.33% was obtained, making the time with the use of the application shorter; finally, concerning the customer satisfaction indicator, 73% of the users who used the application rated their experience as between satisfied and very satisfied.
Low-Power Methodologies and Strategies in VLSI Circuits
Authors: Preethi  , Sapna R.  , Ulla Mohammed Mujeer
Published: March 2023

Due to the fact that low-power gadgets are currently dominating the electronics sectors, researchers are studying their design. Power management is a crucial parameter for designing VLSI circuits since it is essential for estimating the performance of devices, especially those utilized in biomedical and IoT applications. To achieve greater performance, designing a low-power system on a IC is becoming increasingly challenging due to the reduction in size of chip, increases in chip density, and rise in device complexity. Furthermore, for the less than 90 nm node, due to its increasingly complicated design, the total power factor on a chip is turning into a significant difficulty. Leakage current also has a significant effect on how low-power VLSI devices manage their power. Leakage and dynamic power reduction are increasingly being prioritized in VLSI circuit design in order to improve the battery life of electronic portable devices. The many methodologies, tactics, and power management schemes that can be employed for the design of low-power circuit systems are discussed in this chapter.
Low-Power High-Speed Eight-Bit Universal Shift Register Design Using Clock Gating Technique
Authors: Sahu Preeti
Published: March 2023

A register is basically known as a storage device for units in circuits. In data processing systems, they are used to immediately transfer data by using CPU. In digital electronics, shift registers are known as the sequential logic circuits that are used to store data temporally and transfer the data to its output for each and every clock pulse. Shift registers are found as digital memory unit storage in such devices as calculators, computers, etc. Based on shifting data, shift registers are classified in two types: universal shift register and bidirectional shift register. This chapter dealt with design and implementation of 8-bit universal shift register with CG scheme for minimizing power. Circuit operation is performed by Xilinx-14.7 software tool and simulated with I-SIM simulator tool using VHDL language. XPE tool is used to optimize power in the circuit. Results improved the power consumption in circuit by 40.65%. Also 4.76% of area was increased due to adding external circuitry and delay was reduced by 12.93% in the proposed design.
Review of Applications of Energy Harvesting for Autonomous Wireless Sensor Nodes
Authors: Puthran Wilma Pavitra , Prasad Sahana , Gatti Rathishchandra Ramachandra
Published: March 2023

Energy harvesting has been the empowering innovation in the internet of things to power the wireless sensors envisioned to be deployed ubiquitously. In recent decades, there has been an increasing drift towards remote sensor systems from wired networks in commercial and industrial applications due to expensive cabling and their non-feasibility in remote locations. The challenge is to convert these remote sensor systems into self-powered wireless sensor networks using energy harvesters. A brief review of current trends in the applications of energy harvesting in remote sensor systems is discussed in this chapter. A generic architecture of the energy harvesters and their transduction mechanisms and the design methodology of energy harvesters is introduced. The existing business products and the potential prototypes of the energy harvesters with their application domains are reported.
An Enhanced Method for Running Embedded Applications in a Power-Efficient Manner
Authors: Kumar N. M. G. , Ahmad Ayaz , Gowda V. Dankan , Lokesh S. , Kadam Kirti Rahul Rahul
Published: March 2023

Many modern items that are in widespread use have embedded systems. Due of embedded processing's ability to provide complex functions and a rich user experience, it has grown commonplace in many types of electronic products during the last 20 years. Power consumption in embedded systems is regarded as a crucial design criterion among other factors like area, testability, and safety. Low power consumption has therefore become a crucial consideration in the design of embedded microprocessors. The proposed new method takes into consideration both the spatial and temporal locality of the accessed data. In the chapter, the new cache replacement is combined with an efficient cache partitioning method to improve the cache hit rate. In this work, a new modification is proposed for the instruction set design to be used in custom made processors.
Mortgage Financing Frauds in the US
Authors: Polat Ali , Ajmal Muhammad Mobeen , Rafay Abdul
Published: March 2023

In the US, the Consumer Financial Protection Bureau (CFPB) monitors the financial institutions which sell financial products and services to consumers. CFPB ensures that the consumers of financial products receive transparent and competitive services from financial institutions. The chapter contributes to the literature on state-run consumer protection organizations. The CFPB complaint database is used to analyze the performance of CFPB and to find some real-world behaviors of financial institutions from the perceptions of financial consumers. The weaknesses of CFPB are discussed in light of the current social, political, and economic changes happening in the USA. Results show that predatory behaviour is more dominant in non-banking credit and lending institutions. During COVID-19, the people took benefit of others' misery by engaging in manipulative fraud-for-profit schemes. Overall, despite creating awareness, CFPB was not so successful in getting relief for the customer.
Counterfeiting Money and Anti-Counterfeit Measures
Authors: Karataser Busra
Published: March 2023

This study is designed to investigate the use of counterfeit money in the Ottoman Empire. Firstly, the concept of money and the reasons for the use of counterfeit money in the Ottoman Empire are described. Secondly, the reasons for the formation of counterfeit money are examined. Thirdly, the precautions taken against counterfeit money in the Ottoman Empire are discussed. The goal of this study is to investigate the counterfeit money printing incidents that had taken place. Moreover, the anti-counterfeit measures are identified that are implemented by Ottoman Empire to curb this crime and to remove counterfeit money from the market.
Circular VAT Fraud by Transfer of Tax Liability
Authors: Stipić Valentina Vinšalek
Published: March 2023

Tax frauds with fake traders have existed since the 1980s and are certainly not a new phenomenon. Likewise, ways to fight against these frauds have existed since the moment they first appeared. Just as the frauds have evolved over time, so have the proposals for solving them becoming more sophisticated and comprehensive. With the development of the VAT system in the European Union, the methods of fraud are also developing, and over time the EU member states realize that they cannot fight against these frauds alone. The directive on the common system of VAT in 2006 represents the unification and the beginning of the joint fight of the member states of the European Union against these frauds. The EU member states systematically reinforced the measures of the common fraud prevention strategy. One such measure is the transfer of tax liability between the member states of the European Union.