bluuebunny/crossref_metadata_2025 huggingface dataset:
A modern look at the molecular-biological mechanisms of breast tumours in dogs
Authors: Bilyi D. D. , Gerdeva A. А. , Samoiliuk V. V. , Suslova N. I. , Yevtushenko I. D.
Published: May 2020

High morbidity and increase in the number of registrations of breast tumours in dogs, their wide application as biological models, discussion of numerous questions of oncogenesis, and the lack of a uniform/unified methodological approach to the study of molecular and biological mechanisms of treatment of cancer determine the relevance of the problem of cancer both in humans and in our domestic companions. The analysis of publications allowed us to establish the following patterns of carcinogenesis. The peculiarities of the biological behaviour of breast tumours depend on their pathomorphological structure. Genetic predisposition to breast cancer is characteristic only in the single breed aspect. Environmental factors are of critical relevance to carcinogenesis : chemical pollutants initiate oncogenesis indirectly – by altering the expression of several receptors, impaired endocrine balance and direct mutagenic effects. Reproductive status plays a key role in the initiation and progression of breast tumours by reducing the expression of estrogen, progesterone and prolactin receptor genes. The inflammatory response that accompanies the neoplasia process is characterized by increased production of cytokines, cyclooxygenase-2, interleukins (IL-1, IL-6, IL-8), vascular endothelial growth receptors, and impaired hemostatic status (oxidative stress), which promotes progression of disease. In breast cancer in dogs, genomic instability leads to genomic aberrations, and subsequently, mutations that support the proliferation, survival and dissemination of neoplastic cells. The initiation and progression of mammary gland tumours is provided by cancer stem cells by disrupting the regulation of precursor cell self-renewal, which also predispose to resistance to chemotherapeutic agents, radiation, and hormonal cancer therapy. The analysis of the publications revealed the major markers of carcinogenesis that could potentially be used as biological targets for the design of modern diagnostic strategies and high-performance therapeutic protocols.
Polychlorinated biphenyls: Hazardous properties and environmentally sound management in Ukraine
Authors: Ryzhenko N. O. , Bondar O. I. , Chetverykov V. V. , Fedorenko Y. O.
Published: May 2020

Polychlorinated biphenyls are one of the most dangerous compounds for human health and the environment and are included to Annex C of the Stockholm Convention on Persistent Organic Pollutants. Since Ukraine joined the Stockholm Convention in 2007, the National Implementation Plan of the Stockholm Convention provides the environmentally sound disposal of polychlorinated biphenyls, as well as creation of a monitoring system and sharing information about toxicants. Polychlorinated biphenyls’ have fire resistance, low volatility and stability. Therefore, these substances have been widely used in industry, but on the other hand, they are a problem for the environment. The main hazardous properties of polychlorinated biphenyls are bioaccumulation, stability in the environment, the possibility of formation in accidents (especially in fires) of extremely persistent and toxic aromatic compounds, such as dioxins and furans. Toxic responses to polychlorinated biphenyls are: acute lethality; body weight loss; carcinogenesis; dermal toxi­city; fatty liver; genotoxicity; hepatomegaly; immunosuppressive effects; neurotoxicity; porphyria; reproductive and developmental toxicity; thymic atrophy; thyroid hormone-level alterations. The most likely risks of polychlorinated biphenyls contamination in Ukraine are in the areas of operation, repair or storage of electrical equipment. According to quantity, the leading regions for accumulated polychlorinated biphenyls in Ukraine, are Dnipropetrovsk (459 tons), Volyn (280 tons) and Kyiv regions (255 tons). A comprehensive approach to reducing the risk of polychlorinated biphenyls for human health and the environment involves the improvement of the regulatory framework for managing in all stages of “life cycle”. Obtaining complete and accurate information on the volumes and forms of polychlorinated biphenyls accumulation and creation of modern effective technological support for polychlorinated biphenyls’ degradation are a necessary part of environmentally sound management of polychlorinated biphenyls in Ukraine. The “Polychlorinated Biphenyls Database in Ukraine” information system (2017) was created as a National Polychlorinated Biphenyls Registry in Ukraine. It was designed to systematize, structure, and analyze the large amount of information collected during the inventorising of polychlorinated biphenyls. The best technology of polychlorinated biphenyls degradation must not only provides a high degree of polychlorinated biphenyls’ destruction, but also not lead to the formation of new toxic compounds.
Characteristics of immunity to leaf diseases of winter wheat samples under the conditions of the north-east forest steppe of Ukraine a
Authors: Osmachko O. M. , Vlasenko V. A. , Bakumenko O. M. , Bilokopytov V. I.
Published: May 2020

To realize the genetic potential of the productivity of bread winter wheat varieties, it is necessary to maintain a certain level of plant resistance to disease. Resistance donors may lose this property as a result of changes in the virulence of the pathogen and defeat of the genetic systems of plant resistance. This makes it necessary to search for new resistance sources and donors to leaf diseases. Our researches were conducted using field, laboratory and mathematical-statistical methods. Phenological observations, accounting, evaluation and harvesting were conducted according to currently accepted methods. 86 bread winter wheat samples from the 4th WWSRRN CIMMYT were studied for resistance to leaf diseases in our research during 2014–2016. The manifestation of variability depended significantly on the genotype for three diseases. The highest genotype influence was obseved in resistance to septoria dise­ase, where it was 81%. On average the highest indicator of resistance (7.7) to powdery mildew during the three years of research was observed in the mid-late ripening samples. The mid-early ripening group was considered to be the most adapted to the powdery mildew pathogen in the Northeastern Forest-Steppe. The highest average indicator of resistance (7.5) to brown rust for the three years of research was found in the early ripening group. The samples of the mid-ripening group were most adapted to the brown rust pathogen. The highest average resistance to septoria disease was also found in the early ripening group. The best adaptation to septoria disease was observed in mid-late ripening samples. 36% of the samples were resistant to three diseases. As a result of the research, a number of CIMMYT samples were isolated from the 4th WWSRRN, which exceeded the standard in resistance to powdery mildew, brown rust and septoria disease. They were characterized by better performance. Valuable forms for breeding work that can be resistance donors to leaf diseases were identified among them.
Epidemiology and features of the measles course in children during the outbreak of 2018–2019 in the city of Mariupol
Authors: Koniushevska A. A. , Parkhomenko T. A. , Sharunova M. V. , Kazantsev A. B. , Yakovenko D. V.
Published: May 2020

In 2017, Ukraine ranked in the top three among European countries in terms of measles incidence, and ranked first in measles growth in 2018. High morbidity, mortality and development of complications make the problem of knowing features of the measles clinical course, timely diagnosis and active prevention highly relevant. The purpose of the research is to study the dynamics of the incidence and clinical features of measles in children during the outbreak of 2018–2019 in the city of Mariupol, Donetsk region. A peculiarity of the measles outbreak in 2018–2019 in Mariupol is prevalence of the disease in preschool children (60.4%), inclu­ding 30.2% – those under one year of age; low vaccination rate: 52.3% of children unvaccinated; only 22.2% of children were vaccinated twice, according to the schedule. In all age groups, a moderately severe measles course prevailed (69.8%). The clinical course of measles in preschool and school age children had definitive features. Thus, Belsky–Filatov–Koplik spots were observed three times more frequently in preschool children than in schoolchildren (63.9% and 23.3%, respectively). Abdominal pain and diarrhea were only observed in children under 6 years of age (30.2%). Skin pigmentation was absent in children under one year of age and was detected in preschool and school-age children (69.8%). Skin sloughing was only observed in schoolchildren (10.4%). Severe disease course occurred in patients of all ages (29.3%), but children aged under one year and preschool children with severe disease were two times more numerous than those of the school age. Among the observed complications, the vast majority were associated with the respiratory organs: pneumonia (38.3%), subcutaneous emphysema (1.7%), bronchitis (53.2%), laryngitis (3.3%), otitis media (5%). No fatalities were observed. The city should form a commitment to immunization, restore public trust in vaccination, using all forms and means of information, and develop a program to implement the vaccination schedule into practice.
Sensitivity of antifungal preparations of Сandida isolates from sub-biotopes of the human oral cavity
Authors: Osypchuk N. О. , Nastenko V. B. , Shirobokov V. P. , Korotkyi Y. V.
Published: May 2020

Candidiasis is the commonest opportunistic infection of the oral cavity. As a result of immune-deficiency of the organism, yeasts of Candida genus by acting as commensal organisms transmute into pathogenic organisms. The article presents frequency of isolation, topographic peculiarities, species range, sensitivity of the Candida yeasts to antimycotics and newly-synthesized derivatives of amino alcohols isolated from the sub-biotopes of the oral cavity of patients with oncopathologies. The survey of the material included microscopic, mycologic, statistical-analytical methods. For all the clinical isolates the sensitivity to antifungal preparations was determined. Over the study 492 sub-biotopes of the oral cavity were examined. The extraction of the material was made from the mucous membrane of the cheek, angle of the mouth, mucous membrane of the surface of the tongue and the palate. According to the results of the conducted studies, the level of candidal carriage on the mucous membrane of the oral cavity in the patients with oncopathologies without clinical signs of candidiasis equaled 25.0%, active candidiasis infection was found in 47.0% of cases. Among the clinical strains, we isolated: C. albicans, C. glabrata, C. tropicalis and C. krusei. Among all the isolated strains, in all 4 sub-biotopes C. albicans dominated accounting for 73.1%. In 4 sub-biotopes we detected the association of two species of Candida. Analysis of the obtained results of the susceptibility of strains to modern antymicotics and newly-synthesized substances revealed that the representatives of non-albicans are more resistant to the antifungal preparations. Among the commercial preparations, amphotericin B exerted the highest activity against the clinical isolates of yeast-like fungi. The concentration of 0.97 µg/mL inhibited 50.0% of representatives of non-albicans, and also 75.0% of isolates of C. albicans. Fluconazole exhibited activity in the concentration of 1 µg/mL towards 17.0% of non-albicans and 25.0% of С. albicans. Itraconazole was observed to have no significant antifungal activity. Among the newly-synthesized aryl acyclic amino alcohols, compound Kc22 displayed high activity against both groups of Candida (experimental and control) making it promising for creating new therapeutic preparations. The parameters of resistance of clinical isolates to modern antimycotics indicate the necessity of constant monitoring of the sensitivity of the pathogens of candidiasis and precise species identification for rational use of antifungal preparations and prevention of the development of antimycotic resistance.
Antibacterial and fungicidal effect of ethanol extracts from Juniperus sabina, Chamaecyparis lawsoniana, Pseudotsuga menziesii and Cephalotaxus harringtonia
Authors: Zazharskyi V. V. , Davydenko P. О. , Kulishenko O. М. , Borovik I. V. , Kabar A. M. , Brygadyrenko V. V.
Published: May 2020

We determined a high antibacterial effect of ethanol extracts of four species of gymnosperms (Juniperus sabina, Chamaecyparis lawsoniana, Pseudotsuga menziesii and Cephalotaxus harringtonia) against 23 strains of bacteria of families Enterobacteriaceae (Escherichia coli, Enterococcus faecalis, Salmonella typhimurium, S. adobraco, Proteus vulgaris, P. mirabilis, Serratia marcescens, Klebsiella pneumoniae), Staphylococcaceae (Staphylococcus aureus, S. epidermidis), Yersiniaceae (Yersinia enterocolitica), Bacillaceae (Bacillus subtilis, B. cereus), Listeriaceae (Listeria ivanovi, L. іnnocua, L. monocytogenes), Corynebacteriaceae (Corynebacterium xerosis), Campylobacteraceae (Campylobacter jejuni), Nocardiaceae (Rhodococcus equi), Pseudomonadaceae (Pseudomonas аeruginosa) and one strain of fungi of the Saccharomycetaceae family (Candida albicans). The experiment in vitro revealed zone of inhibition of growth of colonies, measuring over 8 mm, produced by ethanol extracts from J. sabina against seven species of bacteria (S. aureus, B. subtilis, B. cereus, L. іnnocua, C. xerosis, Rh. equi and P. аeruginosa), Ch. lawsoniana – against five species (E. coli, B. subtilis, L. іnnocua and Rh. equi), P. menziesii –two species (Rh. equi and P. mirabilis), C. harringtonia – ten species of microorganisms (E. coli, S. aureus, S. epidermidis, L. ivanovi, L. monocytogenes, C. xerosis, C. jejuni, P. vulgaris, S. marcescens and C. albicans). As a result of the research, the most promising plants for further in vivo study of antibacterial activity were C. harringtonia and J. sabina.
Influence of toys on behavioural patterns of pigs and their association with the concentration of serotonin in blood plasma
Authors: Lykhach A. V. , Lykhach V. Y. , Shpetny M. B. , Mykhalko O. H. , Zhyzhka S. V.
Published: May 2020

Improvement of welfare of piglets is one of the key factors which underlie the effectiveness of producing pork and the profitability of pig farming. This article offers a solution to the main industrial problem – creation of comfortable maintenance conditions for pigs using toys which satisfy their ethological needs. Piglets used in the experiment were kept in the swine complex of agricultural production of Agrofirm Mig-Service-Agro Cooperative in Novoodesky district of Mykolaiv Oblast (Ukraine). The objective of the study was assessment of the effect of toys on the behaviour of piglets, level of concentration of hormone serotonin in blood plasma and their energy of growth. The experiment was performed on 120 weaned piglets aged 28 days, which were divided according to the principle of analogues with 60 individuals in each group: I – the control group, the animals were kept with no toys; II – the experimental group, where the animals had toys. During the experiment chronometric monitoring of the piglets’ behavioural acts was carried out using video observation, we extracted blood samples for determination of the content of the hormone serotonin using the method of highly-efficient fluid chromatography and assessed the growth of the piglets. After the end of the experiment, we determined that the presence of toys reduced the intragroup aggression, which was accompanied by decrease in the duration of fights and almost three-fold increase in playing behaviour. Among piglets which had access to toys, the number of individuals observed to bite tails and ears decreased from 11 to 3. In the period of the study, the concentration of serotonin in the blood plasma of piglets who had free access to toys was 10 times higher compared with animals of the control group. Change in the behaviour patterns among the animals of the experimental group led to significant differences regarding the parameters of growth, where probable increase in the live weight at the age of 90 days was observed, which was associated with significant increase in their mean daily weight gain compared with the animals of the control group. This study confirms that use of toys for piglets during growth completion can prevent features of aggression and abnormal forms of stereopathy within groups, increase the live weight and mean daily weight gain and improve emotional condition, which affects the welfare of pigs.
PRODUCTION PERFORMANCE AND SLAUGHTER TRAITS OF AN AUTOSEXING BROILER COMBINATION REARED EITHER SEX SEPARATE OR MIXED
Authors: Mincheva N.
Published: May 2020

Production and slaughter traits of autosexing broiler combination reared either sex separate or mixed were investigated. A total of 180 day-old feather sexed broiler chicks were divided into three groups (n=60)- two sex separate (male and female) and one mixed (1:1), each with two replications of 30 birds. Body weight and feed intake were followed on a weekly basis; the average daily feed intake and feed conversion were calculated. By the end of the experiment (day 49), slaughter analysis was performed on 20 birds: 5 broilers from each of sex separate groups, 5 males and 5 females from the mixed group with live weight close to the group average. The carcass weight (g), weights of carcass cuts, giblets and abdominal fat were determined. Slaughter yield and body parts ratios were calculated. The results demonstrated that sex separate rearing of broilers contributed to higher final body weight - by 6.9 % in females (P<0.05) and by 2.9 % in males (P>0.05), but had no effect on feed conversion. Sex separate rearing resulted in heavier carcasses by 3.6% (P<0.05) and more uniform weight as compared to mixed rearing. The sex effect on body weight and slaughter traits was more considerable in males with respect to carcass, thigh, back, wings and giblets weights (P<0.05) but not abdominal fat whose weight was higher in female broilers (P<0.05). Better uniformity of final body weight of broilers reared sex separate and the reduced variation in carcass weight and weight of cuts (breast and thigh) would facilitate slaughterhouse processing and would contribute to the realization of produce and meeting distribution network demands
Implikasi Pemikiran Ulama Dewan Hisbah PERSIS terhadap Pengembangan Hukum Perkawinan di Indonesia
Authors: Latif Abdul
Published: May 2020

Artikel ini bertujuan menjawab pertanyaan: bagaimana Pemikiran A. Hassan tentang talaq dan ruju’?; apa dasar pemikiran tentang Talaq dan Ruju’?; bagaimana pandangan ulama dewan hisbah PERSIS terhadap pemikiran A. Hassan tersebut?; bagaimana metode istinbat hukum ulama dewan hisbah PERSIS tersebut?; bagaimana implikasi pandangan ulama dewan hisbah PERSIS terhadap perkembangan hukum perkawinan Islam di Indonesia?. Metode penelitian ini menggunakan pendekatan deskriptif kualitatif. Data penelitiannya diperoleh melalui interview para ulama dewan hisbah PERSIS. Menunjukan pertama, menurut A. Hassan perkawinan adalah akad untuk menghubungkan antara laki-laki dan perempuan menjadi suami-istri atas keridhaan bersama, sedangkan talaq adalah akad memutuskan hubungan suami-istri dalam perkawinan, bukan meregangkan. Adapun ruju’ adalah kembalinya mantan suami kepada mantan istrinya pada masa iddah dengan melakukan nikah kembali; kedua, dasar pemikiran A. Hassan tentang talaq dan ruju’ adalah langsung pemahamannya sendiri terhadap alquran dan hadis yang berkaitan dengan hal tersebut. ; ketiga, para ulama dewan hisbah PERSIS berbeda pendapat terhadap pemikiran A. Hassan, ada yang menyetujuinya dan ada yang menyalahinya. Akan tetapi, para ulama dewan hisbah PERSIS sepakat bahwa dalam ruju’ harus ada keridhaan istri pula; ketiga, metode istinbat hukum ulama dewan hisbah PERSIS adalah menggali langsung dari alquran dan hadis dengan menggunakan usul fiqih yang sudah ditetapkan para ulama.
Dewan Perwakilan Daerah Kewenangan Mengusulkan Tanpa Legislasi
Authors: Jasir Anwar
Published: May 2020

Tujuan dari penulisan artikel ini ialah untuk menerangkan bahwa kewenangan Dewan Perwakilan Daerah sebagai suatu lembaga perwakilan rakyat di Majelis Permusyawaratan Rakyat, dimana Dewan Perwakilan Daerah memiliki kewenangan untuk mengusulkan namun tidak memiliki kewenangan legislasi. Metode analisis yang digunakan untuk membahas fokus penelitian ini ialah menggunakan pendekatan kualitatif. Temuan penting dari penelitian ini menunjukan bahwa semenjak lahirnya Dewan Perwakilan Daerah sebagai bagian dari Majelis Permusyawaratan Rakyat hanya memiliki kewenangan untuk mengusulkan saja, namun tidak memiliki kewenangan untuk mengikuti alur berikutnya hingga menetapkan. Tujuan dari penelitian ini ialah pentingnya kewenangan Dewan Perwakilan Daerah untuk memiliki kewenangan hingga ditetapkannya suatu perundang-undangan. Karena Dewan Perwakilan Daerah merupakan refresentative masyarakat dari daerah-daerah yang tentunya dalam proses pembuntukan perundangundangan akan membawa banyak kepentingan di daerah. Dari sinilah bisa dikatakan kalau Dewan Perwakilan Daerah hanyalah sebagai lembaga kedua di parlemen, tidak bisa ikut mengesahkan, menolak dan menunda dari Rancangan Undang-Undang (RUU) yang telah disepakati Dewan Perwakilan Rakyat dan Presiden. Ini sama saja dengan Dewan Perwakilan Daerah tidak memiliki legislasi yang tentunya tidak dapat membawa kepentingan atas keperluan dari daerah yang diwakilkan
Politik Hukum pada Penanganan Tindak Pidana Pemilu
Authors: Andiraharja Diyar Ginanjar
Published: May 2020

Tujuan  penelitian ini adalah untuk mengetahui bagaimana politik hukum pada penanganan tindak pidana Pemilu.  Di mana pada reforrmasi pada sistem dan  Pemilu di Indonesia dirasakan masih dijalankan setengah hati. Pada praksisnya penanganan tindak pidana Pemilu menemukan hambatan, berdasarkan data dari 2.798 dugaan pelanggaran pidana Pemilu yang diregistrasi, kemudian hanya 380 putusan perkara incrahct pidana Pemilu. Metode penelitian menggunakan metode penalaran deduktif. Selanjutnya, data penelitian  ditafsirkan menggunakan cara penafsiran sistematis, yakni menginterpretasi makna lalu mengaitkan norma hukum yang satu dengan norma lain yang dianggap memiliki keterkaitan yakni antara norma-norma hukum yang ditentukan sebagai bahan utama maupun pelengkap. Hasil penelitian ini yakni politik hukum dalam penanganan pidana Pemilu menjadi faktor yang penting untuk membentuk suatu regulasi Pemilu yang lebih baik. Ke depan dibutuhkan suatu regulasi berbentuk undang-undang Pemilu yang dirumuskan secara pasti, jelas, tidak  multitafsir dan memperlakukan semua pihak secara setara (prinsip imparsial), kemudian regulasi tersebut dibutuhkan untuk membentuk penegak hukum yang  profesional, imparsial, dan independen dalam menjalankan fungsi penegakan hukum Pemilu yang diatur secara jelas..
Implementasi Program Pengembangan Karakter Islami Melalui Program Tahfidz
Authors: Paridi Ahmad
Published: May 2020

Artikel ini untuk mengetahui kontruksi nilai-nilai karakter islami, proses pengembangan karakter islami, bentuk evaluasi dalam pengembangan karakter islami, capaian keberhasilan pengembangan karakter islami, faktor yang mempengaruhi program pengembangan karakter islami yang melalui tahfizh. Penelitian ini menggunakan metode pendekatan deskriptif. Hasil penelitian menujukan bahwa kontuksi nilai-nilai pengembangan karakter islami merupakan penyampaian sosialisasi pengembangan karakter, pembudayaan karakter dan internalisasi nilai-nilai karakter islami melaui program tahfidz, Proses pengembangan karakter islami yang dilakukan melalui program tahfizh diawali dengan do’a dan diakhiri dengan do’a pula dengan melakukan pembiasaan-pembiasaan yang ada di SDIT Tahfizh Qur’an Al-Jabar, Evaluasi untuk seluruh siswa akan di tes oleh wali kelas dan guru selalu mengecek dan mengetes seluruh siswa yang telah menghafal Al-Qur’an, Capaian yang menjadi fokus utama adalah terlihat pada prilaku siswa yang berkaitan dengan mencintai Allah, mencintai rasulullah, pekerja keras, berprilaku jujur, memiliki sifat rendah hati, dan bertanggung jawab dan Faktor yang mempengaruhi program pengembangan karakter islami Di SDIT Tahfizh Qur’an Al-Jabar melalui program tahfidz adalah faktor kesehatan, aspek psikologis, faktor kecerdasan, faktor motivasi, faktor usia, dan faktor keluarga.
Penerapan Metodologi Penafsiran Al-Qur’an dalam Dakwah
Authors: RIMI ABDUL RAUF
Published: May 2020

Tidak diragui lagi bahwa turunnya Al-Qur’an kepada Nabi Muhammad saw melalui malaikat Allah swt yaitu jibrail, dan kemudian disebarkan kepada manusia dengan tujuan panduan dan rujukan mereka. Adapun kalam suci itu memacukan kearah supaya di lakukan kajian di dalamnya dengan metode yang sesuai. Ini di sebabkan karena untuk mengelakkan berlakunya salah makna baik dari konteks ayat ataupun maknanya. Kerana kalam suci tersebut sifatnya adalah global yang mana ia memerlukan kepada penjelasan yang detail terhadap sesuatu makna yang terkandung di dalamnya. Maka lahirnya usaha untuk memahaminya. Yang mana ia merupakan berberapa aspek dalam metode penafsiran yang mana ianya terdiri daripada metode ijmali, medote tahlili, metode muqaran dan juga metode maudhui. Adapun persyaratan dalam menjadi mufasir yang terdiri daripada lima belas syarat untuk menjadi mufassir dan untuk menjadi da’I adalah lapan syarat. Apabila persyaratan dipenuhi, maka lengkaplah karekter seorang imuwan dalam bidang agama.
Pengaruh Pembelajaran Integrative Learning (Il) Dan Predict, Discus, Explain, Observe, Discuss (Pdeode) Terhadap Pemahaman Konsep
Authors: Asyhari Ardian , Hariyanti Dina
Published: May 2020

Penelitian ini bertujuan untuk mengetahui pemahaman konsep fisika pada materi besaran fisika dan pengukurannya. Penelitian ini merupakan Quasi Eksperimen Design. Populasi dalam penelitian ini adalah seluruh kelas X. Penelitian dilakukan di SMAN 1 Tegineneng tahun pelajaran 2018/2019, menggunakan dua kelas, yaitu kelas X MIPA 1 sebagai kelas eksperimen I dengan menggunakan pembelajaran dan pembelajaran PDEODE kelas X MIPA 2 sebagai kelas eksperimen II. Teknik pengambilan sampel dilakukan dengan teknik purposive sampling. Instrumen yang digunakan dalam penelitian ini berupa tes berupa soal pilihan jamak beralasan (four tier diagnostic test) untuk pemahaman konsep dan LKPD sebagai pendukung untuk keterlaksanaan model pembelajaran. Analisis data menggunakan SPSS 23.0. Untuk analisa data menggunakan uji normalitas, uji homogenitas, dan Anava dua jalan untuk menguji hipotesisnya terhadap data posttest. Berdasarkan hasil penelitian yang telah dilakukan menunjukkan bahwa pemahaman konsep eksperimen 1 dengan model pembelajaran IL yaitu (63,7), dan untuk kelas eksperimen 2 dengan PDEODE yaitu sebesar (65,28) dan untuk uji hipotesisnya yang pertama adalah (0,93>0,05) A diterima artinya tidak ada pengaruh penggunaan pembelajaran Integrative Learning dan Predict, Discus, Explain, Observe, Discuss, Explain  (PDEODE)  yang kedua yaitu 0.00<0.05 B ditolak artinya ada pengaruh pada pemahaman konsep tinggi dan rendah fisika. Yang ketiga memperoleh 0,75>0,05 A*B diterima artinya  tidak interaksi antara pembelajaran  Integrative Learning dan Predict, Discus, Explain, Observe, Discuss, Explain  (PDEODE) terhadap pemahaman konsep, karena kedua model pembelajaran tersebut sama baiknya untuk diterapkan kedalam pembelajaran kedua kelas eksperimen tersebut.
Pola Komunikasi Masyarakat Adat
Authors: Wibowo Ari
Published: May 2020

Corak budaya, bahasa, dan adat istiadat masyarakat suku Rejang menunjukkan bahwa bangsa Indonesia memiliki kearifan lokal yang bernilai sangat tinggi. Suku Rejang juga dikenal sebagai salah satu suku tertua yang ada di Sumatera. Karakteristik budaya, adat istiadat, dan pola komunikasi masyarakat suku Rejang sangat menarik untuk diteliti  dan ditelaah secara mendalam. Oleh karena itu tepatlah jika metode etnografi komunikasi menjadi landasan utama untuk mengkaji secara mendalam pola komunikasi masyarakat adat suku Rejang. Penelitian ini juga bertujuan untuk menjelaskan dan memahami bentuk-bentuk komunikasi, norma komunikasi, dan kode-kode komunikasi yang terbentuk dalam upacara adat perkawinan suku Rejang. Data kualitatif pada penelitian ini diperoleh melalui berbagai macam teknik pengumpulan data, seperti; wawancara dengan narasumber, analisis dokumen tentang kondisi geografis dan demografis masyarakat suku Rejang, observasi yang telah dituangkan dalam catatan lapangan (transkrip). Penelitian ini juga menggunakan teknik purposive sampling dan snowball sampling. Hasil penelitian ini menunjukkan bahwa bentuk-bentuk komunikasi pada upacara adat perkawinan suku rejang terdiri dari dua bentuk komunikasi yakni, komunikasi verbal dan nonverbal.
Tingkat Partisipasi Masyarakat Terhadap Program Pembangunan Gemma Tapis Berseri Di Kecamatan Kedaton Kota Bandar Lampung
Authors: Asmaria Asmaria , Dewi Lies Kumara , Akbar Muhammad Fikri
Published: May 2020

Menurut surat peraturan dari Walikota Bandar Lampung Nomor 12 Tahun 2006 tentang Program Pembangunan Gemma Tapis Berseri Kota Bandar Lampung, suatu gerakan yang dilakukan oleh dan untuk masyarakat Kota Bandar Lampung, untuk melakukannya secara baik bersama. Dalam upaya pengembangan ekonomi masyarakat. Penggunaan nama Tapis Berseri dalam Gerakan Pembangunan ini dikaitkan juga dengan motto Kota Bandar Lampung. Penelitian ini bertujuan untuk mengetahui sejauh mana pengaruh partisipasi masyarakat terhadap program pembangunan gemma tapis berseri di Kecamatan Kedaton Kota Bandar Lampung. Dalam penelitian ini menggunakan tipe eksplansi yaitu penelitian yang dilakukan untuk menguji hubungan antara dua variabel atau menjelaskan hubungan antara dua variabel. Besarnya pengaruh partisipasi masyarakat terhadap Program Pembangunan Gemma Tapis Berseri adalah sebesar 26,06%, sedangkan dari perhitungan pengujian hipotesis uji t mendapatkan angka sebesar 6,448 dan hasil t tabel pada taraf signifikan 5% sebesar 2,000 dan pada taraf signifikan 1% t tabel sebesar 2,660 sehingga t hitung lebih besar dari t tabel atau 2,000 < 6,448 > 2,660. Dari hasil perhitungan tersebut di atas menunjukkan partisipasi masyarakat berpengaruh positif dan signifikan terhadap Program Pembangunan Gemma Tapis Berseri di Kecamatan Kedaton Kota Bandar Lampung, dengan demikian hipotesis yang penulis ajukan terbukti dan diterima.
Kompetensi Sumber Daya Manusia Islam Pada Bank Syariah
Authors: Meilani Lira Arlia
Published: May 2020

Artikel ini dimaksudkan untuk mengetahui bagaimana kompetensi sumber daya manusia dalam Perbankan Syariah didasarkan pada prinsip syariah Islam. Metode penelitian yang digunakan adalah survei literatur atau studi literatur. Peneliti berhadapan langsung dengan teks (teks) menggunakan data sekunder. Kemampuan untuk melakukan operasi perbankan Syariah sesuai dengan hukum Islam dan prinsip syariah Islam, juga memahami perjanjian syariah yang dikombinasikan dengan prinsip-prinsip Syariah Islam, yang mencakup tidak membebani beban, memberatkan, ketentuan hukum berkala, memperhatikan kesetaraan dan keadilan, serta manfaat.  K
Pengaruh Ekspor dan Impor Terhadap Pertumbuhan Ekonomi dengan Kurs Sebagai Variabel Intervening
Authors: Fauziah Elsa Siti , Khoerulloh Abd. Kholik
Published: May 2020

Penelitin ini bertujuan untuk mengetahui pengaruh ekspor dan impor melalui kurs serta dampaknya terhadap pertumbuhan ekonomi yang diproksikan dengan Produk Domestik Bruto (PDB). Data yang digunakan yaitu laporan kwartal mengenai ekspor, impor, kurs, dan produk domestik bruto tahun 2015-2019. Metode penelitian yang digunakan dengan analisis jalur yang diolah melalui SPSS. Hasil penelitian menunjukkan bahwa variabel ekspor dan impor berpengaruh secara langsung terhadap pertumbuhan ekonomi. Pengaruh secara tidak langsung menunjukkan bahwa ekspor melalui kurs tidak berpengaruh terhadap pertumbuhan ekonomi. Sedangkan impor berpengaruh secara tidak langsung melalui kurs terhadap pertumbuhan ekonomi.
Glycemic Control in Surgery Patients: A Cross-Specialty Educational Intervention for Residents
Authors: Titan Ashley , Baiu Ioana , Church Kacy , Lee Edmund W. , Lau James N.
Published: May 2020

This article was migrated. The article was not marked as recommended. Introduction: Glycemic control in surgical patients with diabetes is critical to their recovery. Residents play a significant role in the management of these patients and glucose control while inpatient. Surgery residents are not trained in diabetes management and there is a significant knowledge deficit of first year surgical residents with regard to perioperative and inpatient diabetes management. Methods: Together with the endocrinology team, we developed an inpatient diabetes management curriculum for incoming surgical residents. The session was incorporated into a larger 2-day intern preparation course given in anticipation of the start of residency. The course is taught by surgery attending physicians and surgical residents and is meant to prepare new interns for common problems that they will encounter on the patient floors. Results: The curriculum was highly rated by residents led to significantly greater comfort and versatility with the management of various types of insulin regimens in surgical patients. Discussion: This study demonstrates the effectiveness of a brief intervention in developing, managing and altering insulin regimens by surgical residents through a multidisciplinary approach. Our curriculum can be easily adopted for other learner groups including all other interns and medical students prior starting their clerkships. The materials created for the curriculum can be downloaded free of charge to be used by other programs.
CAMINHO DA ESPERANÇA NAS RELAÇÕES ENVOLVENDO OS IDOSOS: OLHAR DA COMPLEXIDADE SOB PANDEMIA DO COVID-19
Authors: Hammerschmidt Karina Silveira de Almeida , Bonatelli Lisiane Capanema Silva , Carvalho Anderson Abreu de
Published: May 2020

Objetivo: refletir como relações envolvendo idosos durante uma pandemia COVID-19 sob o olhar de complexidade, vislumbrando o caminho da esperança. Método: Trata-se de uma reflexão, alicerçada na Teoria da Complexidade, segundo Edgar Morin e artigos abordando o Novo Coronavírus. Resultados: Como vivências durante uma pandemia evidenciaram dificuldades econômicas, sociais, de saúde, culturais, éticas e morais em relação aos idosos. Enfrente como incidentes do COVID-19, ensina o que é inevitável na vida individual, coletiva e na história do país e do mundo, gravada pelos medos da humanidade. Portanto, adapte a sociedade e remodele-a que não se relacione com relações com idosos, tradução ou sucesso contra uma doença pandêmica. Isso inclui uma reforma do pensamento, reorganização das compreensões sobre o idoso, que atualmente envolve pensamento disperso, compartimentalizado e excludente. Esta reforma é ampla, profunda, paradigmática, cultural, ética e moral, proposta de anatomia para a cultura da doença, propagação e democratização da poesia do viver, possibilitando aos idosos que se relacionam com belezas de emoções, descubram como verdades por meio de suas próprias coisas primas de suas vidas. No entanto, esta intenção pressiona a metamorfose do individualismo, da opressão e da exclusão, neste contexto, a enfermagem gerontológica é fundamental. Conclusão: como transformações vividas durante uma pandemia, pode ser o prelúdio de mudanças nas relações com os idosos, usando processos transformados e transformadores que coligam-se, com o fortalecimento da enfermagem gerontológica. Quiçá que o momento pandêmico seja o começo do caminho da esperança para novos tempos de dignidade da Humanidade.
Occupational Therapy in times of pandemic: Social security and guaranties of possible everyday life for all
Authors: Malfitano Ana , Cruz Daniel , Lopes Roseli
Published: May 2020

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A Neuroendocrine Tumor Specialty Center in New Orleans’ (NOLANETS) Response to Patient Care During the COVID-19 Pandemic
Authors: Ramirez Robert A. , Bren-Mattison Yvette , Thiagarajan Ramcharan , Boudreaux J. Philip , Marsala Andrew J. , Ryan Pamela , Maluccio Mary A.
Published: May 2020

This commentary outlines the steps taken by the New Orleans Louisiana Neuroendocrine Tumor Specialists to minimize the risk of patient exposure to SARS-CoV-2 but to continue to provide safe, high-quality care during the COVID-19 pandemic.
Long reads nanopore sequencing to recover SARS-CoV-2 whole genome v3
Authors: Resende Paola
Published: May 2020

This protocol describes step-by-step instructions for building long (~2kb) amplicon libraries to recover SARS-CoV-2 genomes using the nanopore sequencing. It can be applied for sequencing on the MinION device or GridION. This protocol was developed in collaboration with the Laboratory of Respiratory Viruses and Measles, Oswaldo Cruz Institute, FIOCRUZ, Brazil, and the two sequencing facilities at Pathogen Genomic Unit (PGU) and UCL Genomics, University College London (UCL), United Kingdom. This document describes the manual steps to perform the protocol, but for further information about the automation of the protocol, please, contact Pathogen Genomics Unit (PGU) - UCL. Manager: Rachel Williams https://www.ucl.ac.uk/infection-immunity/pathogen-genomics-unit This protocol is based on the amplicon tiling strategy described previously by Quick J et al 2017. However, we have applied this strategy to recover long reads (2kb), then some adjustments were performed in the protocol. If you have doubts, we are happy to help you to test or implement the protocol.
A protocol for rapid western-blot: shorten the time to 1-3 hours v2
Authors: Zhao Shenao Biotechnology Company Zhichao , jiang wang
Published: May 2020

Western blot (WB) is a classical and powerful tool to detect the level of interested protein from among a mixture of proteins. Since its invention in 1979, WB is a time-consuming technique that usually needs 1 to 2 days to obtain the result. Here, being aware of the time spent by the researcher, we share a rapid protocol that shortens the time up to 1 hour for detecting the internal loading control protein actin (42kDa) when using the HRP-conjugated anti-actin antibody. Additionally, the time for detecting other (21kDa-100kDa) could be shortened to 3 hours when using the second HRP-conjugated antibody. In conclusion, this rapid protocol dramatically improved the efficiency of WB without increasing the experiment cost or losing its high data quality.
Slice Culture Media v1
Authors: Institute for Brain Science Allen
Published: May 2020

This protocol describes the preparation of Slice Prep Media used for human or mouse slice culture. Note: Research reported in this publication was supported by the National Institute Of Mental Health of the National Institutes of Health under Award Number U01MH114812. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
Ethnic Language Use as a Symbol of Keeping the Nation’s Culture and Traditions (the Case of the Displaced Peoples’ Languages in the Kurdistan Region)
Authors: Ameen Rizgar M. , Magirovskaya Oksana V.
Published: May 2020

The research focuses on the role of ethnic language in keeping culture and traditions of the displaced people who fled to the Kurdistan region of Iraq due to the threats on their lives. It aims at exploring the use of the displaced people’s ethnic language in different occasions in daily activities and the ways it determines the language maintenance and, consequently, favors the displaced peoples’ culture and traditions. It is shown that family, religion, media, emotional and psychological sphere of a human’s life are the domains which can be considered the most effective ones, as ethnic language keeps its dominance there. The novelty of the research is clear due to the vast research interest to such a high migrated region with a changing political situation as Kurdistan. The conducted sociolinguistic analysis of the language situation in this region is the first among its linguistic studies and serves a basis for further research work
Communicative Restrictions in Chinese Academic Discourse
Authors: Burmakina Natalia G. , Detinko Iuliia I. , Nagibina Irina G. , Popova Iana V.
Published: May 2020

The article is devoted to the study of communicative restrictions (taboo) in the academic space of the People’s Republic of China. Taboo in Chinese linguistic culture is based on the dominant principle of Chinese ideology – the principle of “saving of face” (face-saving), which allows people to effectively build harmonious relations in the academic community. The aim of the study is to identify the specifics of communicative restrictions in formal and informal academic communication within the framework of asymmetric, unequal, relations (“teacher – student”, “research supervisor – student”) and symmetrical, equal, relations (“teacher – teacher”, “student – student”). With the help of ethnographic, descriptive, and contextual analysis methods, the authors identify and present seven most relevant topics of taboo functioning in the process of formal and informal academic interaction. The results of the study can be used in theoretical and practical courses on communicative linguistics, discursive linguistics and discourse analysis, pragmalinguistics and intercultural communication. In addition, the work may be useful in developing cross-cultural trainings in the framework of interaction with China on academic mobility programs
Interpretations of the Mythologeme “Tree-Cross” in Old English
Authors: Proskurin Sergei G. , Proskurina Anna V.
Published: May 2020

The topicality of the appeal to the interpretation of a tree-cross mythologeme is caused by the change of the pagan worldview into Christian. The development of ideas about the Christian sign is complex, in one of the approaches to transforming the tree-cross, a part of the overcome ideas about the world as space around the world axis is preserved, i.e. the world tree. The coming era of Christianity inherits this view, and the cross itself appears as a world axis that defines the coordinates of space. The purpose of the article is to show the evolutionary semiotic row, which represents both Christian and pagan symbolism. Initially, the cross appears as a motivated view. Then the terms of the denotative plan appear, devoid of pagan connotations of the tree-cross type. In general, in the evolution of the term continuity is traced, one designation is replaced by another. For some time, the second item copies the functions and forms of the first, replacing it in the subject line. The cross as an object of worship in Christianity replaces the world tree. All new nominations of the cross are associated with the motivation of the world as the center where the altar is installed, which was initially presented in the tradition as a world tree, and then became designated by the cross. The cross, as the main Christian symbol, often appears as made of wood and is identified with the cosmic world tree growing directly into heaven. Research methods which are used in this article are as follows: philological analysis of the text and semiotic analysis of texts. The set of communicatively relevant factors that determine the statement, as well as the situational and contextual relevance of the lexical meaning, are taken into account. In turn, the necessary initial amount of communicatively relevant information is obtained on the basis of linguistic methods. In particular, data from an etymological analysis are involved. The research material was provided by the Old English written monuments accessible to the modern researcher. Texts in other Indo-European languages are occasionally referred; they act as a background showing some parallels
Sociocultural and Linguistic Contexts of the Russian Sign Language Functioning in Krasnoyarsk Krai
Authors: Kulikova Liudmila V. , Shatokhina Sofya A.
Published: May 2020

The article contains an ethnographic description of the conditions governing the use of the regional sign language in Krasnoyarsk Krai within the modern sociolinguistic context. The subject of the discussion is the problem of the linguistic design of sign languages in general, including some features of Russian Sign Language. The study provides statistical information and legal norms for the use of this iconic communication system. A study of the current state of Russian Sign Language functioning in Krasnoyarsk Krai allows us to talk about a change in the status of this sign language, an increasing interest in issues related to its applied significance, and reinforces the need to develop new theoretical approaches to its institutionalization
Influence of cognitive load on the expression of the emotional stroop effect
Authors: Kutsenko T.
Published: May 2020

The Emotional Stroop Effect (ESE) is the result of a greater delay in naming colors of written emotional words than colors of written neutral
words, because of shifting attention to emotionally meaningful information. ESE is mainly used in psychopathology surveys, but its application is also promising for solving applied psychophysiological problems, from professional screening and neuromarketing to detecting lies and detecting threats from emotionally unstable individuals. Because the ESE is sensitive to testing conditions, various modifications to the Emotional Stroop Test (EST) have been investigated. Within the subtests, neutral and emotional (negatively coloured) words were presented. The inclusion of distractors in subtests (target words, names of plants and animals that were not required to be answered by keystrokes) complicates the task, which manifests itself in a considerable extension of the reaction time. When performing a task with significant cognitive load, the left hand responds to emotional stimuli longer than the right. The results obtained may indicate the formation of a special system for processing emotional information in the right hemisphere, while the left hemisphere focuses on the cognitive task. It is likely that in the case of increased cognitive load, the subsystems for processing emotional and cognitive information operate relatively autonomously, inter-hemispheric interaction is enhanced, and functional asymmetry is reduced. As cognitive pressure decreases, functional asymmetry is likely to increase inter-hemispheric interaction, and ESE is not detected. The obtained values of latent periods of reaction to emotionally significant and neutral stimuli can be used to develop scales and criteria for evaluating a person's emotional reactions when it is needed.