bluuebunny/crossref_metadata_2025 huggingface dataset:
La doble normatividad de la Constitución de 1978: la Transición como momento evolutivo del ser social español
Authors: García Eloy
Published: July 2021

En el presente artículo se plantea una crítica a la tesis que define la Transición política española como un exitoso intento de poner punto final a la “ley del péndulo” que había venido rigiendo nuestra historia constitucional. Por un lado, esta tesis minusvalora las condiciones de la situación española de 1978, marcada por el tránsito entre dos mundos, el moderno que heredaba y el emergente postmoderno, que se convertiría en una realidad incuestionable a partir de 1989. Además, la Constitución española de 1978 se redactó en un momento en que estaban declinando los supuestos conceptuales político-normativos del paradigma constitucional dominante en Europa tras la Segunda Guerra Mundial
El trienio antisistema (2015-2017) del nacionalismo catalán
Authors: Ortega Gutiérrez David
Published: July 2021

En el presente artículo se estudian las principales actuaciones de los tres años (2015-2017) del gobierno y el parlamento catalán que culminan con la declaración unilateral de independencia del día 27 de octubre de 2017. Nos centramos principalmente en las siguientes cuestiones: el llamado derecho a decidir; el apoyo (o no) internacional y de la Unión Europea al proyecto secesionista catalán; la (in)viabilidad económica del mismo; la ruptura del marco jurídico, social y democrático en Cataluña y parte de la batalla informativa que ha rodeado al proyecto secesionista.
Modernización de las Fuerzas Armadas durante el reinado de Juan Carlos I
Authors: Puell de la Villa Fernando
Published: July 2021

El principal objetivo del artículo será contemplar y analizar escueta y globalmente el proceso de modernización de las Fuerzas Armadas en los últimos decenios del siglo XX, así como poner de relieve la obligada interdependencia entre aquel y el cambiante entorno político-social e internacional. A tal efecto, se prestará atención a los cuatro principales hitos del citado proceso: reorganización de la superestructura española de defensa; reforma de la organización y revisión de las funciones encomendadas a los ejércitos; inserción de España en los organismos defensivos occidentales, y homologación de la justicia militar con la ordinaria.
La fotografía de Arturo Cerdá y Rico como herramienta para la interpretación y puesta en valor del paisaje.
Authors: Fernández-Portela Julio , López-Rodríguez Ramón
Published: July 2021

Los procesos ambientales, sociales y culturales inciden en el paisaje presentado cambios con el paso del tiempo. De su conocimiento depende, en buena medida, la salvaguarda de sus valores, y un estudio profundo de su evolución requiere la intervención de factores naturales y culturales, materiales e inmateriales, tangibles e intangibles. Este trabajo presenta dos objetivos, por un lado, poner en valor la fotografía de Cerdá y Rico y, por otro, diseñar con ella una ruta turística por la localidad de Cabra del Santo Cristo (Jaén). La fotografía histórica sirve al doble propósito de estudiar el paisaje y poner en valor los recursos del espacio geográfico, por ello, el legado fotográfico de Arturo Cerdá y Rico resulta fundamental, y a través de las imágenes y del trabajo de campo, se delimitarán y georreferenciarán los principales hitos de este recorrido con la herramienta Wikiloc. El resultado es el diseño de una ruta de unos 5,5 km dividida en diez tramos con más de 45 hitos que recogen los recursos patrimoniales existentes en el territorio.
The suitability of foreign language teaching in childhood according to the CLIL approach: the foreign language teachers' attitudes
Authors: Smajla Tilen
Published: July 2021

This paper presents the results of a research into the foreign teachers' attitudes towards the first foreign language (FL 1) teaching according to the CLIL approach. The first foreign language teachers (FL 1 teachers) should have carried out their FL 1 lessons using the CLIL approach. The results of the twelve interviews: teachers agree upon the importance of the education process of teachers-to-be, for any teacher working at an early level should have completed a BA in class teaching and should have acquired a degree in the methodology of early language teaching. Most teachers who used the CLIL approach in the first year of its introduction (school year 2014–2015), refrained from it in the second year, or only used some elements of the CLIL approach, for they felt that it was impossible to follow the guidelines of the “hard” CLIL. Consequently, they only used some elements or strategies of the CLIL approach, which some authors call “soft” CLIL. Although some teachers claimed to have encountered numerous obstacles in teaching according to CLIL, they nevertheless considered it to be a suitable approach in the FL 1 classroom.A well-prepared abstract enables the reader to identify the basic content of a document quickly and accurately, to determine its relevance to their interests, and thus to decide whether to read the document in its entirety.
Views of Turkish EFL teacher trainees toward technology-integrated PBL practices
Authors: Kırkgöz Yasemin , Turhan Burcu
Published: July 2021

Problem-Based Learning (PBL) is increasingly becoming popular in teacher education, just like the prevalence in the use of Modular Object Oriented Dynamic Learning Environment (Moodle) which is an instructional socio-constructivist online tool providing collaborative learning. PBL where learning occurs through real-life problem solving practices is also included in the constructivist approach. This study was designed as a mixed methods research which English as Foreign Language (EFL) teacher trainees were involved in PBL through Moodle with the aim of solving problems related to language teaching and learning which they encountered at practicum schools. Participants were 93 EFL teacher trainees studying at a state university in Turkey. The study aimed to reveal the participants’ views of their PBL experiences within the scope of a Materials Evaluation and Adaptation Course. Data were collected through questionnaires and interviews; and analyzed through descriptive statistics and content analysis consecutively. Results demonstrated that the teacher training activities delivered through PBL yielded promising benefits for EFL teacher trainees’ professional development despite some minor flaws faced in the process. Thus, PBL can be considered as a useful method to deliver such courses offered in any branches of teacher education.
Supporting families with their child's sleep
Authors: Boddy Bethany
Published: July 2021

Health visitors play a central role in assessing and supporting families to manage sleep concerns; but with little evidence-based guidance on managing infant sleep difficulties this can be challenging, says Bethany Boddy
Nurse parasite clinics and the benefits of routine testing
Authors: Wright Ian , Richmond Philippa
Published: July 2021

Cats and dogs are infected with a wide range of parasites, many of which are capable of causing or contributing to disease. Veterinary nurses play a vital role in helping to formulate parasite control plans for pets. Routine diagnostic testing alongside risk-based appropriate preventative treatment is important for efficacy of treatment to be monitored, screening for sub-clinical parasitic infections and drug resistance and to demonstrate that current parasite control recommendations are adequate. A wide range of diagnostic tools are available to veterinary practices and this article considers some of the diagnostic techniques available for routine parasite diagnosis and how they might be used in parasite prevention plans for cats and dogs.
Does Size Matter? Animal, Living and Non-Living Classification, Implications for Teaching
Authors: Espinoza Fernando
Published: July 2021

An empirical investigation of elementary school teacher candidates on classification activities dealing with animate and inanimate objects in terms of being living or non-living demonstrates that as the size of the objects increases, subjects are more likely to classify them correctly as either being an animal or having living characteristics. Despite a variety of misconceptions having an impact on the results, size magnitude is shown to play a significant role on proper classification. The subjects’ performance on these activities at an advanced stage of their preparation suggests that their factual and procedural knowledge are deficient due to a lack of opportunities for conceptual development of the items tested. The identification of the role of size on the proper classification of objects in the activities bears significantly on the science curricular structure at the elementary school level. As the results of this study indicate, both pre-service elementary school teachers and by extension their prospective students need longer practice dealing with living and non-living classification activities, particularly in tasks where the microscopic features of matter can be investigated so that the proclivity to regard size as the defining characteristic is effectively addressed.
Tipos de mediación parental del uso de las TIC y su relación con la cibervictimización del alumnado de educación primaria
Authors: López Castro Leticia , Priegue Diana , López-Ratón Mónica
Published: July 2021

INTRODUCCIÓN. Las familias asumen, constantemente, nuevos desafíos educativos derivados de la necesidad de educar a los menores en el uso, cada vez más generalizado, de las tecnologías. Las estrategias educativas familiares que lo regulan se conocen como mediación parental. Existen cuatro tipos de mediación parental en función del uso de estrategias de regulación-control y de comunicaciónapoyo: a) mediación parental negligente (bajo grado de regulación-control y de comunicación-apoyo); b) mediación parental permisiva-indulgente (bajo grado de regulación-control, pero alto de comunicación- apoyo); c) mediación parental restrictiva-autoritaria (elevado grado de regulación-control, pero bajo de comunicación-apoyo); y d) mediación parental democrática (elevado grado de regulacióncontrol y de comunicación-apoyo). El objetivo principal del estudio es conocer si existe algún tipo de relación estadísticamente significativa entre estos tipos de mediación parental basados en el uso de estrategias de regulación-control y comunicación-apoyo y la cibervictimización del alumnado que cursa 5.º o 6.º de educación primaria. MÉTODO. Una muestra de 1.169 familias de 26 centros educativos de Galicia (España) fue encuestada a través de un cuestionario autoadministrado que mide tanto la mediación parental en función del uso de estrategias de regulación-control y de comunicación-apoyo en ocho situaciones habituales de uso de las tecnologías por los menores, así como la cibervictimización del alumnado. Los análisis llevados a cabo con el programa estadístico SPSS Statistics se basaron en la prueba de asociación no paramétrica chi-cuadrado (χ²) y el coeficiente de correlación de Spearman para conocer tanto la dirección como el grado de las asociaciones. RESULTADOS. Los resultados obtenidos nos permitieron identificar una relación estadísticamente significativa entre el tipo de mediación parental y la cibervictimización, obteniendo frecuencias de cibervictimización inferiores cuando nos referimos al tipo de mediación parental democrática, pero superiores para la mediación negligente, permisiva-indulgente y restrictiva-autoritaria. DISCUSIÓN. Se discuten las implicaciones para la intervención educativa, concluyendo que los programas de prevención del ciberacoso deben incluir estrategias de mediación parental que potencien la comunicación y el apoyo intrafamiliar.
International Vocational Education and Training Research: An Introduction to the Special Issue
Authors: Gessler Michael , Bohlinger Sandra , Zlatkin-Troitschanskaia Olga
Published: July 2021

The seven articles in this special issue represent a wide range of international comparative and review studies by international research teams from China, Germany, India, Russia, Switzerland and Mexico. The presented projects are part of the national program "Research on the Internationalisation of Vocational Education and Training", funded by the German Federal Ministry of Education and Research (BMBF).  An adapted version of Urie Bronfenbrenner’s ecological systems theory forms the conceptual framework of the special issue. The four system levels (micro, meso, exo and macro) are addressed by one article each. The article on the microsystem level focuses on the intended and implemented curricula in a cross-country comparison of China and Russia. The article on the mesosystem level aims at the development of a quality management model for vocational education and training (VET) institutions in India. At the exolevel, the regional structures of the education and employment systems in Mexico, particularly the cooperation between schools and companies in the hotel industry, are investigated. At the macrosystem level, the social representation of non-academic labour in Mexico is examined in terms of cultural artefacts. Furthermore, three overarching review studies systematise relevant research developments and approaches. The topics of the three review studies are European VET policy, transfer of VET and VET research. The scope ranges from the development of a comparative research tool to a summary analysis of over 5,000 individual publications. Given the broad scope and heterogeneity of the findings, a summative conclusion would hardly be appropriate. Nevertheless, with regard to the model of the ‘triadic conception of purposes in comparative VET research’ that represents a heuristic for describing the purposes of international VET research, we conclude with an emphasis on a need of more criticality. In this context, one finding can be pointed out as an example: One review study found that most studies (here, with reference to VET transfer) refer to the recipient country without a comparative perspective. Thus, there is a clear demand for more comparative research following a critical-reflective approach.
Single-shot 4-step phase-shifting multispectral fringe projection profilometry
Authors: Omidi Parsa , Najiminaini Mohamadreza , Diop Mamadou , Carson Jeffrey J. L.
Published: July 2021

Phase-shifting profilometry (PSP) is considered to be the most accurate technique for phase retrieval with fringe projection profilometry (FPP) systems. However, PSP requires that multiple phase-shifted fringe patterns be acquired, usually sequentially, which has limited PSP to static or quasi-static imaging. In this paper, we introduce multispectral 4-step phase-shifting FPP that provides 3D imaging using a single acquisition. The method enables real-time profilometry applications. A single frame provides all four phase-shifted fringe patterns needed for the PSP phase retrieval algorithm. The multispectral nature of the system ensures that light does not leak between the spectral bands, which is a common problem in simultaneous phase-shifting with color cameras. With the use of this new concept, custom composite patterns containing multiple patterns can be acquired with a single acquisition.
Optical feedback linear cavity enhanced absorption spectroscopy
Authors: Tian Jianfei , Zhao Gang , Fleisher Adam J. , Ma Weiguang , Jia Suotang
Published: July 2021

A simple and universal technique for performing optical feedback cavity enhanced absorption spectroscopy with a linear Fabry-Pérot cavity is presented. We demonstrate through both theoretical analysis and experiment that a diode laser can be sequentially stabilized to a series of cavity modes without any influence from the direct reflection if the feedback phase is appropriately controlled. With robust handling of the feedback phase and help from balanced detection, a detection limit of 1.3 × 10−9 cm−1 was achieved in an integration time of 30 s. The spectrometer performance enabled precision monitoring of atmospheric methane (CH4) concentrations over a time period of 72 h.
Roadmap for the unobscured three-mirror freeform design space
Authors: Bauer Aaron , Rolland Jannick P.
Published: July 2021

In rotationally symmetric lens design, there are rule-of-thumb boundaries on field-of-view and aperture for well-known design forms that provide valuable information to the designer prior to starting a design. In the design space of unobscured three-mirror imagers, freeform optics have been shown to provide a significant benefit over conventional surface shapes, but the degree to which they improve the performance for any given combination of field-of-view, entrance pupil diameter, and F-number remains unknown. Thus, designers of these systems are not afforded any pre-design information to inform their specification decisions. Here, we designed over 200 systems to establish a first-of-its-kind roadmap of specification ranges over which an unobscured three-mirror imager using freeform surfaces can achieve diffraction-limited performance in the visible spectrum. The scalability of the findings to the infrared regions of the spectrum is also addressed.
Acoustic-resolution photoacoustic microscopy based on an optically transparent focused transducer with a high numerical aperture: erratum
Authors: Fang Cheng , Zou Jun
Published: July 2021

This erratum corrects a few numbers in Table 1 of the original paper, Opt. Lett. 46, 3280 (2021).OPLEDP0146-959210.1364/OL.423287
The kinetic landscape of nucleosome assembly: A coarse-grained molecular dynamics study
Authors: Brandani Giovanni B. , Tan Cheng , Takada Shoji
Published: July 2021

The organization of nucleosomes along the Eukaryotic genome is maintained over time despite disruptive events such as replication. During this complex process, histones and DNA can form a variety of non-canonical nucleosome conformations, but their precise molecular details and roles during nucleosome assembly remain unclear. In this study, employing coarse-grained molecular dynamics simulations and Markov state modeling, we characterized the complete kinetics of nucleosome assembly. On the nucleosome-positioning 601 DNA sequence, we observe a rich transition network among various canonical and non-canonical tetrasome, hexasome, and nucleosome conformations. A low salt environment makes nucleosomes stable, but the kinetic landscape becomes more rugged, so that the system is more likely to be trapped in off-pathway partially assembled intermediates. Finally, we find that the co-operativity between DNA bending and histone association enables positioning sequence motifs to direct the assembly process, with potential implications for the dynamic organization of nucleosomes on real genomic sequences.
α-Gal immunization positively impacts Trypanosoma cruzi colonization of heart tissue in a mouse model
Authors: Rodrigues da Cunha Gisele Macêdo , Azevedo Maíra Araújo , Nogueira Denise Silva , Clímaco Marianna de Carvalho , Valencia Ayala Edward , Jimenez Chunga Juan Atilio , La Valle Raul Jesus Ynocente , da Cunha Galvão Lucia Maria , Chiari Egler , Brito Carlos Ramon Nascimento , Soares Rodrigo Pedro , Nogueira Paula Monalisa , Fujiwara Ricardo Toshio , Gazzinelli Ricardo , Hincapie Robert , Chaves Carlos-Sanhueza , Oliveira Fabricio Marcus Silva , Finn M. G. , Marques Alexandre Ferreira
Published: July 2021

Chagas disease, caused by the parasiteTrypanosoma cruzi, is considered endemic in more than 20 countries but lacks both an approved vaccine and limited treatment for its chronic stage. Chronic infection is most harmful to human health because of long-term parasitic infection of the heart. Here we show that immunization with a virus-like particle vaccine displaying a high density of the immunogenic α-Gal trisaccharide (Qβ-αGal) induced several beneficial effects concerning acute and chronicT.cruziinfection in α1,3-galactosyltransferase knockout mice. Approximately 60% of these animals were protected from initial infection with high parasite loads. Vaccinated animals also produced high anti-αGal IgG antibody titers, improved IFN-γ and IL-12 cytokine production, and controlled parasitemia in the acute phase at 8 days post-infection (dpi) for the Y strain and 22 dpi for the Colombian strain. In the chronic stage of infection (36 and 190 dpi, respectively), all of the vaccinated group survived, showing significantly decreased heart inflammation and clearance of amastigote nests from the heart tissue.
The impact of artificial selection for Wolbachia-mediated dengue virus blocking on phage WO
Authors: Dutra Heverton L. C. , Ford Suzanne A. , Allen Scott L. , Bordenstein Sarah R. , Chenoweth Stephen F. , Bordenstein Seth R. , McGraw Elizabeth A.
Published: July 2021

Wolbachia is currently at the forefront of global efforts to control arbovirus transmission from the vector Aedes aegypti. The use of Wolbachia relies on two phenotypes—cytoplasmic incompatibility (CI), conferred by cifA and cifB genes in prophage WO, and Wolbachia-mediated pathogen blocking (WMPB). These traits allow for local, self-sustaining reductions in transmission of dengue (DENV) following release of Wolbachia-infected A. aegypti. Here, aided by previous artificial selection experiment that generated Low and High pathogen blocking lines, we examined the potential link between WMPB and phage WO. We found no evidence that Wolbachia or phage WO relative densities predict DENV blocking strength across selected lines. However, selection resulted in reduced phage WO relative density for the Low WMPB line. The Low blocking line was previously shown to have reduced fitness as a result of selection. Through subsequent genomic analyses, we demonstrate that SNP variation underpinning selection for low blocking led to elevated frequency of potential deleterious SNPs on chromosome 1. The key region on chromosome 1 contains genes relating to cell cycle regulation, oxidative stress, transcriptional pausing, among others, that may have cascading effects on Wolbachia intracellular environment. We hypothesize that reduction in phage WO may be driven by changes in the loci directly under selection for blocking, or by the accumulation of predicted deleterious alleles in linkage disequilibrium with blocking loci resulting from hitchhiking. For the Low line with fewer phage WO, we also detected reduced expression of cifA and cifB CI genes, with patterns of expression varying between somatic and reproductive tissues. In conclusion, we propose that artificial selection for WMPB trait had corresponding impacts on phage WO densities, and also the transcription of CI-causing genes. Future studies may include a more detailed analysis of the regions the A. aegypti chromosome 1’s ability to affect WMPB and other Wolbachia-associated intrinsic factors such as phage WO.
Comparative transcriptome analysis of unripe and ripe banana (cv. Nendran) unraveling genes involved in ripening and other related processes
Authors: Kaur Karambir , Awasthi Praveen , Tiwari Siddharth
Published: July 2021

Banana is one of the most important fruit crops consumed globally owing to its high nutritional value. Previously, we demonstrated that the ripe pulp of the banana cultivar (cv.) Nendran (AAB) contained a high amount of pro-vitamin A carotenoids. However, the molecular factors involved in the ripening process in Nendran fruit are unexplored. Hence, we commenced a transcriptome study by using the Illumina HiSeq 2500 at two stages i.e. unripe and ripe fruit-pulp of Nendran. Overall, 3474 up and 4727 down-regulated genes were obtained. A large number of identified transcripts were related to genes involved in ripening, cell wall degradation and aroma formation. Gene ontology analysis highlighted differentially expressed genes that play a key role in various pathways. These pathways were mainly linked to cellular, molecular and biological processes. The present transcriptome study also reveals a crucial role of up-regulated carotenoid biosynthesis pathway genes namely, lycopene beta cyclase and geranylgeranyl pyrophosphate synthase at the ripening stage. Genes related to the ripening and other processes like aroma and flavor were highly expressed in the ripe pulp. Expression of numerous transcription factor family genes was also identified. This study lays a path towards understanding the ripening, carotenoid accumulation and other related processes in banana.
Firms’ challenges and social responsibilities during Covid-19: A Twitter analysis
Authors: Patuelli Alessia , Caldarelli Guido , Lattanzi Nicola , Saracco Fabio
Published: July 2021

This paper offers insights on the major issues and challenges firms face in the Covid-19 pandemic and their concerns for Corporate Social Responsibility (CSR) themes. To do so, we investigate large Italian firms’ discussions on Twitter in the first nine months of the pandemic. Specifically, we ask: How is firms’ Twitter discussion developing during the Covid-19 pandemic? Which CSR dimensions and topics do firms discuss? To what extent do they resonate with the public? We downloaded Twitter posts by the accounts of large Italian firms, and we built the bipartite network of accounts and hashtags. Using an entropy-based null model as a benchmark, we projected the information contained in the network into the accounts layers, identifying a network of accounts. We find that the network is composed of 13 communities and accounts at the core of the network focus on environmental sustainability, digital innovation, and safety. Firms’ ownership type does not seem to influence the conversation. While the relevance of CSR hashtags and stakeholder engagement is relatively small, peculiarities arise in some communities. Overall, our paper highlights the contribution of online social networks and complex networks methods for management and strategy research, showing the role of online social media in understanding firms’ issues, challenges, and responsibilities, with common narratives naturally emerging from data.
The gap in contraceptive knowledge and use between the military and non-military populations of Kinshasa, DRC, 2016–2019
Authors: Akilimali Pierre Z. , Nzuka Henri Engale , LaNasa Katherine H. , Wumba Angéle Mavinga , Kayembe Patrick , Wisniewski Janna , Bertrand Jane T.
Published: July 2021

Introduction

The objective of this study is to assess change over time in the modern contraceptive prevalence rate (MCPR) and related variables among married women of reproductive age (15–49 years) in the military population in Kinshasa, Democratic Republic of Congo, compared to women in the non-military population, based on cross-sectional surveys in 2016 and 2019.

Methods

Data among women living in military camps were collected as a special study of contraceptive knowledge, use, and exposure to FP messaging, for comparison to women in the non-military population from the annual PMA2020 survey. Both used a two-stage cluster sampling design to randomly select participants. This analysis is limited to women married or in union. Bivariate and multivariate analysis was used to compare the military and non-military populations.

Results

The socio-demographic profile of women in the military camps differed between 2016 and 2019, which may reflect the more mobile nature of this population. In both populations, knowledge of modern contraceptive methods increased significantly. Similarly, use of a modern contraceptive method also increased significantly in both, though by 2019 women in the military camps were less likely to use modern contraception (24.9%) than their non-military counterparts (29.7%). Multivariate analysis showed no significant difference in the amount of increase in MCPR for the two populations. Among contraceptive users in both populations, the implant was the leading method. Potential effects of FP programming were evident in the military population: exposure to FP messaging increased (in comparison to a decrease among the non-military population). Moreover, women who had lived in the camps for 4+ years had a higher MCPR than those living in the camps for less than four years.

Conclusions

This study demonstrates the feasibility and importance of collecting data in military camps for better understanding contraceptive dynamics among this specialized population.
Incidence of malignant transformation in the oviductal fimbria in laying hens, a preclinical model of spontaneous ovarian cancer
Authors: Paris Elizabeth A. , Bahr Janice M. , Bitterman Pincas , Basu Sanjib , Abramowicz Jacques S. , Barua Animesh
Published: July 2021

Ovarian high grade serous carcinoma (HGSC) is a lethal form of ovarian cancer (OVCA). In most cases it is detected at late stages as the symptoms are non-specific during early stages. Emerging information suggests that the oviductal fimbria is a site of origin of ovarian HGSC. Currently available tests cannot detect ovarian HGSC at early stage. The lack of a preclinical model with oviductal fimbria that develops spontaneous ovarian HGSC is a significant barrier to developing an early detection test for this disease. The goal of this study was to examine if the oviductal fimbria in hens is a site of origin of HGSC and whether it expresses several putative markers expressed in ovarian HGSC in patients. A total of 135 laying hens (4 years old) were selected from a flock using transvaginal ultrasound (TVUS) imaging, followed by euthanasia and gross examination for the presence of solid masses and ascites. Histological types of carcinomas were determined by hematoxylin and eosin staining. Expression of WT-1, mutant p53, CA-125, PAX2 and Ki67 in normal or malignant fimbriae or ovaries were examined using immunohistochemistry, immunoblotting and gene expression assays. This study detected tumors in oviductal fimbriae in hens and routine staining revealed ovarian HGSC-like microscopic features in these tumors. These tumors showed similarities to ovarian HGSC in patients in expressing several markers. Compared with normal fimbriae, intensities of expression of WT-1, mutant p53, CA-125, and Ki67 were significantly (P<0.05) higher in fimbrial tumors. In contrast, expression of PAX2 decreased gradually as the tumor progressed to late stages. The patterns of expression of these markers were similar to those in ovarian HGSC patients. Thus, tumors of the oviductal fimbria in hens may offer a preclinical model to study different aspects of spontaneous ovarian HGSC in women including its early detection.
Postgraduate pharmacist development- an evaluation of Jordanian pharmacist experiences to inform and shape an evidence-based professional development policy
Authors: Odeh Mohanad , Alkhader Enas , McCloskey Alice , Aljabra Rabia , Al-sharayri Mohammad , Al-Noimi Faisal , Alarmooti Majid , Alzu’bi Mutazbellah
Published: July 2021

Building capacity for developing skills as leadership, teamwork, and continuous academic support has become essential for fulfilling a successful pharmacy career. This study aims to assess Jordanian pharmacists’ views on professional development, namely: the continuous education infrastructure, strategies and programs for personal development, leadership skills, incentive schemes, drug information resources and digital services. As well as exploring options for better academic support delivered to pharmacists. To capture participant’s views, an online validated and reliable survey was developed. Non-probability sampling design was used. Participants were qualified pharmacists working at Royal Medical Services (RMS) and Community Pharmacists (CP). Comparison and descriptive statistics were used to report the results. A total of 271 pharmacists participated, 144 from RMS (8% more than the needed sample) and 127 CP (7% more than the needed sample). There was a strong desire amongst both RMS and PC groups for continuous educational training particularly in the following areas, first: Advanced counselling and communication skills (means = 8.99±0.145, CI 95% = 3.70–4.28 and 9.37±0.096, CI 95% = 4.18–4.56). Second: Personal development skills (mean = 8.92±0.142, CI 95% = 3.64–4.20 and 9.02±0.145, CI 95% = 3.73–4.30). Third, Pharmaceutical health promotion (mean = 8.05±0.180, CI 95% = 2.70–3.41 and 8.57±0.159, CI 95% = 3.26–3.89). Only 19.4% and 18.1% of the RMS and CPs respectively reported the presence of a written policy for personal development and leadership in their workplace. There were few incentives for pharmacists to participate in research. Few pharmacists used the available drug information and toxicology centers. The professional and continuous personal development of pharmacists support an evolving healthcare system. This study emphasizes the need for a tailored and documented postgraduate educational strategy, personal development, and leadership skills training in Jordan. Implementing a well-defined scheme of incentives should be encouraged to engage pharmacists in continuous professional development programs and pharmaceutical research. Such strategy and training should enhance both professional and personal performance.
Modeling the mediating roles of self-directed learning and knowledge management processes between emotional intelligence and learning outcomes in higher education
Authors: Shafait Zahid , Khan Muhammad Asif , Bilan Yuriy , Oláh Judit
Published: July 2021

Objective: Drawing on the knowledge-based view and ability-based theories of emotional intelligence (EI), in this study, we investigate the effects of EI on learning outcomes related to academics and administrators in Chinese research universities and we also test the direct association between learning outcomes and creative performance. In addition, we examine the mediating role of self-directed learning (SDL) and knowledge management processes (KMPs) on the relationship between EI and learning outcomes. Methods: The sample, for this study, consisted of 547 academic and administrative personnel at Chinese higher educational institutions (HEIs), and the hypothesized associations were examined through partial least squares structural equation modeling. Results: Our results indicated that EI has no significant influence on learning outcomes. However, an indirect relationship between EI and learning outcomes is established through SDL and KMPs. Conclusions: This study strengthens the professional understanding of EI and supports that the personnel at HEIs should value SDL and KMPs, which in turn enhances their learning outcomes. Although EI has received increased importance in higher education institutions, there are few studies that have investigated the relationship of EI, SDL, KMP, and learning outcomes. This is one of the initial studies that has empirically examined the interface of EI and learning outcomes in HEIs and also provides timely insights into the understanding of the mediating role of SDL and KMP.
Photons from NIR LEDs can delay flowering in short-day soybean and Cannabis: Implications for phytochrome activity
Authors: Kusuma Paul , Westmoreland F. Mitchell , Zhen Shuyang , Bugbee Bruce
Published: July 2021

Photons during the dark period delay flowering in short-day plants (SDP). Red photons applied at night convert phytochromes to the active far-red absorbing form (Pfr), leading to inhibition of flowering. Far-red photons (greater than 700 nm) re-induce flowering when applied after a pulse of red photons during the dark period. However, far-red photons at sufficiently high intensity and duration delay flowering in sensitive species. Mechanistically, this response occurs because phytochrome-red (Pr) absorbance is not zero beyond 700 nm. We applied nighttime photons from near infrared (NIR) LEDs (peak 850 nm) over a 12 h dark period. Flowering was delayed in Glycine max and Cannabis sativa (two photosensitive species) by 3 and 12 days, respectively, as the flux of photons from NIR LEDs was increased up to 83 and 116 μmol m-2 s-1. This suggests that long wavelength photons from NIR LEDs can activate phytochromes (convert Pr to Pfr) and thus alter plant development.
A new bottom-up method for the standard analysis and comparison of workforce capacity in mental healthcare planning: Demonstration study in the Australian Capital Territory
Authors: Furst Mary Anne , Salinas-Perez Jose A. , Gutiérrez-Colosia Mencia R. , Salvador-Carulla Luis
Published: July 2021

The aims of this study are to evaluate and describe mental health workforce and capacity, and to describe the relationship between workforce capacity and patterns of care in local areas. We conducted a comparative demonstration study of the applicability of an internationally validated standardised service classification instrument—the Description and Evaluation of Services and Directories—DESDE-LTC) using the emerging mental health ecosystems research (MHESR) approach. Using DESDE-LTC as the framework, and drawing from international occupation classifications, the workforce was classified according to characteristics including the type of care provided and professional background. Our reference area was the Australian Capital Territory, which we compared with two other urban districts in Australia (Sydney and South East Sydney) and three benchmark international health districts (Helsinki-Uusima (Finland), Verona (Italy) and Gipuzkoa (Spain)). We also compared our data with national level data where available. The Australian and Finnish regions had a larger and more highly skilled workforce than the southern European regions. The pattern of workforce availability and profile varied, even within the same country, at the local level. We found significant differences between regional rates of identified rates of psychiatrists and psychologists, and national averages. Using a standardised classification instrument at the local level, and our occupational groupings, we were able to assess the available workforce and provide information relevant to planners about the actual capacity of the system. Data obtained at local level is critical to providing planners with reliable data to inform their decision making.
CD97 stabilises the immunological synapse between dendritic cells and T cells and is targeted for degradation by the Salmonella effector SteD
Authors: Cerny Ondrej , Godlee Camilla , Tocci Romina , Cross Nancy E. , Shi Haoran , Williamson James C. , Alix Eric , Lehner Paul J. , Holden David W.
Published: July 2021

The Salmonella enterica effector SteD depletes mature MHC class II (mMHCII) molecules from the surface of infected antigen-presenting cells through ubiquitination of the cytoplasmic tail of the mMHCII β chain. This requires the Nedd4 family HECT E3 ubiquitin ligase Wwp2 and a tumor-suppressing transmembrane protein adaptor Tmem127. Here, through a proteomic screen of dendritic cells, we found that SteD targets the plasma membrane protein CD97 for degradation by a similar mechanism. SteD enhanced ubiquitination of CD97 on K555 and mutation of this residue eliminated the effect of SteD on CD97 surface levels. We showed that CD97 localises to and stabilises the immunological synapse between dendritic cells and T cells. Removal of CD97 by SteD inhibited dendritic cell-T cell interactions and reduced T cell activation, independently of its effect on MHCII. Therefore, SteD suppresses T cell immunity by two distinct processes.
Guía de viajes alrededor de la alcoba de Vicente Quirarte
Authors: Ballester Pardo Ignacio
Published: July 2021

Vicente Quirarte (Ciudad de México, 1954) reunió algunos de sus ensayos sobre viajes, viajeros y caminos literarios en Viajes alrededor de la alcoba (1993). Este libro toma por título la máxima de otro poeta mexicano, Xavier Villaurrutia. Desarrolla la idea clásica de quien se mueve desde su habitación con la lectura de crónicas que le llevan a imaginar un mundo más saludable. A partir de ciertos motivos itinerantes que recorre Vicente Quirarte —como el flâneur de Charles Baudelaire o Walter Benjamin, el doppelgänger de Arthur Rimbaud, el homeless de Leopold Bloom o Die Verwandlung de Franz Kafka— estableceremos una poética de la ecocrítica urbana que se viene defendiendo en la lírica mexicana. La reescritura genera un diálogo constante entre diversos tiempos y espacios. Atendemos a distintas perspectivas del viaje: como proceso de escritura, desde la historia o la arquitectura, el viaje físico o conjetural, hasta llegar a la infancia como separación, iniciación y retorno. Si nos fijamos en la tradición que hereda y renueva el poeta, advertimos un elogio del espacio urbano (Ciudad de México, Praga o Nueva York) y de los animales (el perro, la ballena o las hormigas) en contra de ese final voluntario que es el suicidio. Se trata de elementos también presentes en Alejandro Tarrab o Esther M. García. La literatura permite establecer un viaje interior que beneficie a la vida en comunidad, con una conciencia del medio, solo entre la multitud.
Siriusly Concerned: Animal Non-Belongingness in a Dichotomized Environment
Authors: Fernández Caro Jesús
Published: July 2021

This article approaches Sirius (1944), by Olaf Stapledon, from a perspective that brings together literary animal studies and ecocriticism. The eponymous main character of this science fiction novel is a genetically-modified dog who struggles between the human and the animal realms, being unable to belong to either urban or natural spaces. I argue this work of fiction carries out an exercise of blurring boundaries, thus proposing alternatives for harmful binaries such as human-animal, city-nature, or divine-mundane. Each of these binaries is explored in three trips of the many this character experiences throughout the novel. This allows the main character to reflect on his peculiar, unique species as the singularity he is. Sirius claims it is only empathy that can help in such a task; both human and nonhuman animals are then able to rejoice in biological, cultural, and spiritual differences. Sirius’s trips are analyzed in order to look closely at (1) the dog’s reflections on humankind while being in London, (2) his becoming a wolf, dog, and human at the same time in the woods, and (3) music as the ideal tool to articulate one’s spirituality based on a reconnection with an almost lost biodiversity.
A merőlegesen viszonyuló vegyes állat: maszkulinitás, homoszexualitás és transzszexualitás metszéspontjai a kazovszkiji életműben
Authors: Hajnal Zsolt
Published: July 2021

A dolgozat maszkulinitás, homoszexualitás és transzszexualitás metszéspontjait vizsgálja El Kazovszkij autobiografikus életművében. Az elemzés során nem hagyományos műértelmezés történik, sokkal inkább két kazovszkiji terminus, a „merőleges viszony”, illetve a „vegyes állat” jelentéstartalmának megvilágítása kapcsán a kazovszkiji szubjektivitás elméleti keretben történő tematizálására teszek kísérletet. A maszkulinitást strukturáló meleg férfitekintet elemzése után maguknak a transzmaszkulinitásoknak a sajátosságait tekintem át. A kazovszkiji idol(ok) eltárgyiasításának problémáját követően Jay Prosser és Judith Halberstam megtestesülésre vonatkozó polémiájának kapcsán a cisznemű férfitest fenomenológiai tapasztalatának a kazovszkiji szubjektivitásban szerepet játszó lényegiségét mutatom be. Kazovszkij testnarratívája alkalmat ad az otthonra találás (transzszexuális) narratívája és a határmenti létezés (queer) hontalansága közti ontológiai különbözőségek egyértelműsítésére, egyben lehetővé teszi, hogy rámutassak az egyik legtöbbet idézett Kazovszkij-értelmezés, Forgács Éva Kazovszkij-monográfiájának vitatható állításira.
VALIDITY OF THREE-DIMENSIONAL PHOTONIC SCANNING TECHNIQUE FOR ESTIMATING PERCENT BODY FAT
Authors: SHITARA K. , KANEHISA H. , FUKUNAGA T. , YANAI T. , KAWAKAMI Y.
Published: July 2021

Background:Three-dimensional photonic scanning (3DPS) was recently developed to measuredimensions of a human body surface. Objective:The purpose of this study was to explore the validity of bodyvolume measured by 3DPS for estimating the percent body fat (%fat). Design, setting, participants, andmeasurement:The body volumes were determined by 3DPS in 52 women. The body volume was corrected forresidual lung volume. The %fat was estimated from body density and compared with the corresponding referencevalue determined by the dual-energy x-ray absorptiometry (DXA). Results:No significant difference was foundfor the mean values of %fat obtained by 3DPS (22.2 ± 7.6%) and DXA (23.5 ± 4.9%). The root mean squareerror of %fat between 3DPS and reference technique was 6.0%. For each body segment, there was a significantpositive correlation between 3DPS- and DXA-values, although the corresponding value for the head was slightlylarger in 3DPS than in DXA. Residual lung volume was negatively correlated with the estimated error in %fat.Conclusions:The body volume determined with 3DPS is potentially useful for estimating %fat. A possiblestrategy for enhancing the measurement accuracy of %fat might be to refine the protocol for preparing thesubject’s hair prior to scanning and to improve the accuracy in the measurement of residual lung volume.
Protecting Traditions with Modernization: Community Empowerment in Rejowinangun through the Village of Traditional Herbal Medicine Destination
Authors: Sriharini Sriharini , Syafira Shofwah
Published: July 2021

This article aims to provide another perspective on the concept of community empowerment by utilizing local potential with cultural value combined with a tourism-based empowerment pattern. Herbal medicine as a hereditary heritage in Rejowinangun village is optimized for marketing in the concept of a tourist village, thereby increasing its economic value in a modern society. To achieve this goal, this study uses a qualitative method with a phenomenological approach to capture the context of changes experienced by the community to see the significance of the empowerment model. The results of this study indicate that the process of developing the production of herbal medicine as a processed product of herbal plants is produced through the use of land owned by the community. The expertise of the Rejowinangun village community in concocting traditional herbal medicine is produced from hereditary inheritance. As a form of re-actualization in the marketing system, modern methods were introduced, from the concept of a tourist village to marketing herbal medicine in the form of instant packaging. Modernization steps in all aspects as part of empowerment have an impact on increasing the economic value of these products, so that they have an impact on improving the community in the economic, social, cultural, environmental and health fields. The integration between the concept of cultural preservation and modern management in community development that takes place in the village of Rejowinangun has proven to be effective and efficient, so that this method can be a new alternative in group-based community development that still preserves local traditions and keeps up with the times.
Potency, Participation, and Development: Insights from Sustainable Tourism of Setigi in Sekapuk Village, Indonesia
Authors: Waridah Nurrotun
Published: July 2021

Community-Based Tourism (CBT) has become a new trend for local-based development. However, many villages have not developed this potentiality as a new commodity as a tourism-based community. For this reason, this article explains three important elements in the development of community-based tourism in the Sekapuk Village community, Gresik Regency, East Java, namely following the potential, participation, and development of Setigi tourism. This research highlights three critical issues concerning i) how the role of local communities in maximizing village potential, ii) how Community-Based Tourism practices work effectively in increasing community social awareness, and iii) how communities build new tourist destinations. The research method using observation in Setigi tourism, interviews with village leaders, managers of Tourism Awareness Group/Kelompok Sadar Wisata (Pokdarwis), local traders, and visitors. The indication of community has built Setigi tourist destinations by utilizing the potential of nature. Meanwhile, CBT is implemented in environmental conservation, tourism training, accessibility of transformation, and the development of communication systems. Setigi tourism is built based on social participation, which results in nature-based tourism destinations, the development of the Mbok Inggih kitchen, and the home industry. As a successful tourist village development, the village has achieved the icon of the Millionaire Village. Nevertheless, in the end, Setigi tourism still has limitations in optimizing the socio-cultural and socio-religious potential.