bluuebunny/crossref_metadata_2025 huggingface dataset:
Religion Against Violence: Insights of Contemporary Philosophy and Eastern Patristics
Authors: Chistyakova Olga Vasilievna
Published: November 2024

This article examines the concepts of violence and religion as social phenomena of modernity. Religion and the church are presented not as specific organizations or denominations, but as important social institutions and are reflected in philosophical and anthropological terms. I carry out the idea that religion as a modern social institute in cooperation with other social communities can resist violence, especially its aggressive forms. Based on some philosophical theories, the causes of the emergence of the different forms of social violence, as well as definitions of violence, are explored. In this context, the article presents the ideas of Hanna Arendt, Carl von Clausewitz, Bertrand de Jouvenel, James Mill, and Max Weber. Special attention is paid to the conception of the mimetic origin of aggression and violence in “primitive” or “archaic religions” elaborated by the French philosopher René Girard. He compares the social roots of aggression and violence in these religions with the Biblical ones and prefers the latter for their potential in preventing and overcoming the imitation types of violence. Girard’s anthropological justification of the mentioned historical religious traditions is presented. A significant part of the paper is devoted to the views of the Eastern Church Fathers of Early Christianity, considered in the concurrence of their humanistic ideas with those of noted contemporary philosophers. I see meaningful ideas for preventing extreme forms of violence and aggression in the contemporary world in the doctrines of the Early Eastern and Byzantine Fathers, especially those of the classical patristic period. In this regard, this article presents the anthropological and humanistic teachings of Athanasius the Great, Gregory of Nazianzus, Maximus the Confessor, and John of Damascus. The Early Church Fathers’ ideas are analyzed from a philosophical point of view, as having rational and anthropological grounds which are relevant for the present day’s human existence.
Iterative Separation of Blended Seismic Data in Shot Domain Using Deep Learning
Authors: Ma Liyun , Han Liguo , Zhang Pan
Published: November 2024

Accurate deblending techniques are essential for the successful application of blended seismic acquisition. Deep-learning-based deblending methods typically begin by performing a pseudo-deblending operation on blended data, followed by further processing in either the common-shot domain or a non-common-shot domain. In this study, we propose an iterative deblending framework based on deep learning, which directly addresses the blended data in the shot domain, eliminating the need for pseudo-deblending and domain transformation. This framework is built around a unique architecture, termed WNETR, which derives its name from its W-shaped network structure that combines U-Net and Transformer. During testing, the trained WNETR is incorporated into the iterative framework to extract useful signals iteratively. Tests on synthetic data validate the effectiveness of the proposed deblending iterative framework.
Investigation of Possible Sources of Electrodermal Activity in Surgical Personnel to Assess Workplace Stress Levels
Authors: Schlender Merle , Uslar Verena , Uppenkamp Stefan , Tabriz Navid , Weyhe Dirk , Cetin Timur
Published: November 2024

Objective: The aim of this study was to evaluate alternative measurement points to assess stress levels during surgery, given that taking electrodermal activity (EDA) measurements from the palms, a commonly used standard, is impractical in surgical contexts. Methods: A combination of mentally challenging tasks on a laparoscopy trainer (LapSim) and physically challenging sports exercises were performed by a group of participants. During these tasks, EDA was measured at three different locations: the fingers, toes, and shoulder/neck area. Additionally, an electrocardiogram was used as an objective measure of stress levels. Results: The findings indicated that EDA measurements taken at the toes produced similar high skin conductance levels to measurements taken at the palms. However, significantly lower skin conductance levels were observed at the shoulder. Despite this, the cross-correlation of EDA data revealed high correlation coefficients (above 0.96) between both the toe and shoulder measurements when compared to the palm data. Conclusions: The study concludes that both the toes and the shoulder/neck area serve as viable alternative locations for assessing occupational stress levels in surgical personnel. This assertion is supported by the similarity of the data produced by these methods to that of the standard finger-based technique, with the latter still being identified as the most sensitive method for capturing EDA. Subsequently, these findings attest to the potential for practical adaptation of this technique in surgical contexts.
The Impact of Low-Carbon City Governance on Firm Green Innovation: An Enterprise Life Cycle Perspective
Authors: Wang Bangpei , Wu Zihao , Wang Yufang
Published: November 2024

In order to address the climate change crisis, China has actively promoted low-carbon urban development. China has implemented a policy known as the low-carbon city pilot policy (LCCPP). Given the enterprise life cycle theory, a multi-period DID model is employed to investigate the influence of the LCCPP on enterprise’s green technology innovation (GTI). The research reveals that the LCCPP can actually promote enterprise’s GTI. The LCCPP significantly stimulates GTI of enterprises in the growth phase, but not for enterprises in the maturity and recession phases. Path analysis indicates that the LCCPP can enhance enterprise’s GTI by increasing government fiscal subsidies to and research and development (R&D) of firms. Further analysis reveals that although the GTI effects of the LCCPS are not effective for state-owned enterprises (SOEs) and non-manufacturing businesses, it is significant for those enterprises that are in the growth stage. The LCCPP successfully enhances substantial innovation within enterprises, but not for strategic innovation within enterprises. This study enriches the existing scholarly research on the influence of the LCCPP on enterprise’s GTI and holds practical implications for promoting accurate and effective GTI among enterprises, thereby further advancing the transition towards low-carbon urban development.
Time Series Perspective on the Sustainability of the South African Food and Beverage Sector
Authors: Masena Thabiso E. , Mahlangu Sarah L. , Shongwe Sandile C.
Published: November 2024

This study aims to quantify and graphically illustrate the negative lingering effect that the COVID-19 pandemic had on the sales in South African Rands (ZAR) of the food and beverage sector using the time series seasonal autoregressive integrated moving average with exogenous components (SARIMAX) intervention model. The SARIMAX2, 1, 00, 1, 212 intervention model provided the best fit, supported by the lowest values of the model selection and error metrics (Akaike’s information criterion, Bayesian information criterion, and root mean square error). The total estimated loss of sales in the 52 months during the intervention period (March 2020 to June 2024) amounts to ZAR 130,579 million. The most affected months were April 2020 and May 2020 with estimated losses of ZAR 7719 million and ZAR 7633 million, respectively. The findings of this study align with the Statistics South Africa® statistical report based on empirical estimation without any model fitting, thus highlighting the effectiveness of the SARIMAX intervention model in quantifying the effects of the pandemic. The lingering negative impact of the COVID-19 pandemic still continues to threaten the sustainability of the South African food and beverage sector, violating the United Nations’ Sustainable Development Goal, Number 2, which is to end hunger, achieve food security, improve nutrition, and promote sustainable agriculture.
Behavior of the Electricity and Gas Grids When Injecting Synthetic Natural Gas Produced with Electricity Surplus of Rooftop PVs
Authors: Ademollo Andrea , Carcasci Carlo , Ilo Albana
Published: November 2024

Distributed generation and sector coupling are key factors for economic decarbonization. Because gas networks have a large storage capacity, they have attracted the attention of power engineers to use them to increase the flexibility and security of supply in the presence of renewable and distributed energy resources. This paper makes the first attempt to integrate the electricity and gas systems to fill available gas storage facilities with synthetic natural gas on a large scale. This synthetic natural gas can then be used to operate gas turbines and to compensate for the fluctuating production of renewable energy sources. The LINK-holistic architecture, which integrates renewable and distributed energy resources, is used in this work. It facilitates sector coupling, which means power-to-gas and gas-to-power, throughout the entire power grid and at the customer level. This work is limited to investigating the power-to-gas process at the prosumer level. The electricity surplus of rooftop PVs is used to produce synthetic natural gas, fed into the gas grid after covering the local gas load. The behaviors of the electricity and gas grids are investigated. Results show that electricity prosumers may also become prosumers of synthetic natural gas. The current unidirectional gas grids should be upgraded with compressors at pressure reduction groups to turn them bidirectional, allowing synthetic natural gas storage in the existing large gas storage appliances after considering the pipes’ linepack effect. The proposed solution could make it possible to fill the underground storage plants in summer, when the electricity and synthetic natural gas production exceed electrical and gas demand, respectively.
The Detection and Analysis of Microplastics in a Typical Mountainous Drinking Water System in China
Authors: Xu Chaoxing , Pan Lingzhen , Zhai Linfu , Wang Wenlong , Lu Kejia , Zhu Jianqiang , Xia Guanghua
Published: November 2024

Microplastics (MPs) are widely detected in urban drinking water systems. However, the presence and characteristics of MPs in mountainous drinking water systems with independent and simple filtration facilities have been overlooked. In this study, we revealed the ubiquity of MPs and demonstrated that their concentrations increased along with the pipeline length in Bainitan Village, Tiantai County, China. The simple filtration facility in this village did not effectively remove most MPs. Polyethylene, polyurethane, and polyethylene terephthalate were the dominant polymers in water samples (72.32% in total), while polyvinylchloride, polyurethane, and polyethylene were the most prevalent in the sediment (74.00% in total) of the reservoir. Long fragments were the predominant shape of MPs in all samples, with the majority being smaller than 100 μm. The estimated daily intake of MPs through drinking water ingestion was highest in infants (2.14–31.26 MPs/kg bw/day), compared to children (1.41–20.67 MPs/kg bw/day) and adults (1.05–15.35 MPs/kg bw/day), highlighting their increased vulnerability. This emphasizes the need for advanced water treatment systems in mountainous regions. It also underscores the necessity for government attention to improve water safety in remote areas. Our research will contribute valuable baseline data for further research on MP exposure, particularly in mountainous communities.
Identification of the Emerging C1-like Lineage of Enterovirus A71 in Two Uruguayan Children with Hand-Foot-and-Mouth Disease and Neurological Complications
Authors: Lizasoain Andrés , Martínez Natalia , de Mora Carla , Rodríguez Edivia , Ledezma Nathalie , Colina Rodney
Published: November 2024

Enterovirus A71 (EV-A71) is a major cause of hand-foot-and-mouth disease (HFMD), particularly in cases that involve complications affecting the nervous system or cardiopulmonary function. In South America, EV-A71 has primarily been identified through studies of acute flaccid paralysis (AFP) and other neurological disorders. In September 2022, two children from a small city in Uruguay were hospitalized with presumptive rhombencephalitis, exhibiting symptoms of HFMD. EV-A71 was identified through RT-PCR and next-generation sequencing of stool and skin lesion samples. A maximum-likelihood phylogenetic analysis of the P1 coding region classified the Uruguayan strains as part of an emerging lineage, primarily reported in Europe over the past decade, known as the C1-like lineage. The findings presented here represent the first detection of the EV-A71 C1-like lineage in cases of HFMD and encephalitis reported from South America, underscoring the urgent need to enhance surveillance for HFMD, aseptic meningitis, encephalitis, and AFP, in countries facing challenges in establishing effective surveillance programs related to enteroviruses and associated diseases.
Effects of Guanidine Acetic Acid on the Growth and Slaughter Performance, Meat Quality, Antioxidant Capacity, and Cecal Microbiota of Broiler Chickens
Authors: Li Xuedan , Chen Zhimin , Li Jiantao
Published: November 2024

The objective of this research was to assess the impact of guanidine acetic acid (GAA) on the growth performance, slaughter outcomes, meat quality, antioxidant capacity, and cecal microbiota of broiler chickens. A total of 128 Arbor Acres broilers were randomly divided into two experimental groups. One group served as the control and was provided with a standard diet, whereas the group treated with GAA received a diet enhanced with 400 mg/kg of GAA. The duration of the experiment was 42 days. Measurements for growth performance, serum biochemical parameters, and antioxidant capacity were conducted both during and at the conclusion of the study, while assessments of slaughter performance and meat quality were carried out solely at the end. Notable differences were observed in terms of growth performance, blood biochemistry, and metabolic parameters between the control and GAA-treated groups (p < 0.05). Hence, these findings imply that dietary GAA supplementation can favorably affect growth, carcass quality, biochemical indicators, and antioxidant capacity in broiler chickens.
Electrocoagulation as a Remedial Approach for Phosphorus Removal from Onsite Wastewater: A Review
Authors: Reza Arif , Haller Shannon , Mao Xinwei
Published: November 2024

Onsite wastewater treatment systems (OWTSs), although essential for managing domestic sewage in areas without centralized sewerage treatment plants, often release phosphorus (P) into the environment due to inadequate treatment. This unregulated P discharge exacerbates water quality degradation and jeopardizes aquatic habitats and human health. Among different treatment technologies, electrocoagulation (EC) demonstrates considerable potential for addressing this challenge by efficiently removing P from OWTSs and thus protecting water resources and ecological integrity. Through electrochemical reactions, EC destabilizes and aggregates P-bearing particles, facilitating their removal through precipitation. Compared to conventional treatment approaches, i.e., chemical and biological methods, EC offers several advantages, including high efficiency, minimal chemical usage, and adaptability to varying wastewater compositions. This review underscores the urgent need for mitigating P discharge from OWTSs and the efficacy of EC as a sustainable solution for P removal, offering insights into its mechanisms, reactor design considerations, important operational factors, performance, and potential applications in OWTSs as well as providing future research directions.
Determination and Optimization of Aerobic and Anaerobic Decomposition of Paper Sludge
Authors: Samešová Dagmar , Poništ Juraj , Pochyba Adam , Hýrošová Tatiana , Schwarz Marián , Veverková Darina
Published: November 2024

The processing of paper sludge is currently an important environmental topic due to its high global production. The aim of this study is to monitor the biodegradation of paper sludge when the initial conditions change. Biodegradability tests 301F and OECD 311 were used to determine biodegradation. The data obtained from the tests were subsequently obtained for the simulation in MATLAB R2023b. The highest aerobic decomposition was approximately 80% after 28 days at an initial concentration of paper sludge leachate of 76 g/L. By simulating 3D modelling, we can predict that with a retention time of 1 day with degradation under aerobic conditions at the level of 70%, the ideal initial concentration of organic substances will be 157.55 g/L. Based on this model, it is possible to estimate that with a biogas production of 554 m3/tVS and a decomposition time of 20 days, it is necessary to set a concentration of approximately 128 g/L. Based on biodegradability tests, paper sludge was evaluated as suitable for aerobic or anaerobic biological decomposition.
Barriers to diagnosing and treating vulval lichen sclerosus: a survey study
Authors: Crew Arabella , Leatherland Rheanne , Clarke Louise , Owen Caroline , Simpson Rosalind C
Published: November 2024

Background

Vulval lichen sclerosus (VLS) is a chronic inflammatory condition that is frequently misdiagnosed and under-recognised. To date, qualitative research has focused on lived experience of VLS, with women attributing diagnostic delay to poor interactions with healthcare professionals (HCPs), often due to lack of knowledge. In the UK, women with VLS are most likely to present to primary care.

Aim

To establish HCPs’ perspectives on the identification, management, and education of vulval skin disease, with a focus on VLS.

Design and setting

A mixed-methods study survey undertaken across the UK.

Method

HCPs were recruited through opportunistic sampling. The survey was distributed via email and WhatsApp through professional networks and in hard-copy format at events, and completed between 1 November 2023 and 14 December 2023. Data were analysed using descriptive statistics, Spearman’s rank correlations, and thematic analysis.

Results

Of 122 responders, most were GPs (n= 53) and GP trainees (n= 59). In total, 37.7% of responders had never participated in teaching or learning on vulval skin disease. Confidence in the identification of vulval skin disease positively correlated with experience, exposure, and female gender, although this last correlation was weak. The top identified barriers to diagnosis and treatment included lack of knowledge, embarrassment, and absence of VLS diagnostic criteria. Almost all participants (97.5%) felt that VLS diagnostic criteria would be helpful in clinical practice.

Conclusion

This study provides insight into the barriers to diagnosing and treating VLS in primary care. HCPs recognise deficiencies in training and referral pathways, and a lack of tools to support VLS diagnosis. Training should include skills to address stigma and embarrassment. This study highlights the importance of developing interventions, such as reproducible diagnostic criteria, to overcome barriers, thereby expediting diagnosis and treatment.
The social determinants of distress in South Asian men with long-term conditions: a qualitative study
Authors: Awan Hassan , Corp Nadia , Kingstone Tom , Chew-Graham Carolyn A.
Published: November 2024

Background: People with long-term physical conditions are more likely to experience distress, depression or anxiety. Physical-mental comorbidity is associated with lower quality of life, poorer clinical outcomes, and increased mortality than physical conditions alone. South Asians (SAs) are the largest minority group in the UK, and more likely to have long-term conditions (LTCs) such as diabetes and heart disease. Aim: To explore how men of SA origin with LTCs understand and experience emotional distress as well as the experiences of GPs supporting them. Design and setting: UK qualitative study interviewing SA men with diabetes or coronary heart disease, and GPs working at practices with higher proportions of SAs. Method: Online semi-structured interviews with SA men and GPs. Data were analysed via reflexive thematic analysis. Topic guides were modified iteratively as data collection and analysis progressed. An ethnically appropriate patient advisory group of SA men was involved in all stages of the research. Results: Seventeen SA men with LTCs and 18 GPs were interviewed. Participants described contextualising distress including the interaction between having a LTC and distress, and the intersections of social determinants of distress including ethnicity, poverty and perceptions of prejudice. Participants understood distress as different to depression with the need to negotiate multiple identities as well as alternative paradigms of health. Conclusion: This study highlights the influence of social determinants of distress in SA men with LTCs. It provides an insight into how primary care has the potential to address health inequalities by considering the intersection of these factors.
The Influence of Marketing Mix and Brand Image on Repurchase Intention and Consumer Satisfaction
Authors: Carolina Rika
Published: November 2024

This study examines the influence of the marketing mix and brand image on consumer satisfaction and repurchase intention in Kampung Pempek 26 Ilir, a designated center for purchasing pempek and souvenirs in Palembang. The research aims to identify key factors that drive repeat visits and improve sales for this tourism and culinary destination. A quantitative approach with descriptive analysis was utilized, targeting residents of Palembang who have visited Kampung Pempek 26 Ilir. A total of 210 respondents were selected using accidental sampling. Data analysis measured the direct and mediated effects of the marketing mix and brand image on consumer satisfaction and repurchase intention. The marketing mix showed a positive and significant influence on repurchase intentions and consumer satisfaction. When mediated by consumer satisfaction, the marketing mix had an additional positive effect on repurchase intention. Brand image also significantly influenced repurchase intention and consumer satisfaction. Findings suggest that both the marketing mix and brand image are crucial in enhancing consumer satisfaction and encouraging repeat visits to Kampung Pempek 26 Ilir. The positive mediation effects of consumer satisfaction indicate its role as an essential bridge between marketing strategies and consumer loyalty. The study concludes that improving both the marketing mix and brand image can substantially enhance consumer satisfaction and repurchase intention. Specifically, consumer satisfaction is a pivotal factor in increasing consumer loyalty and the likelihood of repeat purchases. The recommendation for Kampung Pempek 26 Ilir is to invest in optimizing its marketing strategies and brand image to enhance consumer satisfaction. Further studies could explore additional factors that influence consumer loyalty in similar cultural and culinary tourism centers.
Perfil epidemiológico das internações por Espinha Bífida de 2013 a 2023
Authors: Moreira Andressa Franco , Motta dos Anjos Jorge Luís , Ferraz Moreira Jader
Published: November 2024

Objetivo. Descrever o perfil epidemiológico das internações por espinha bífida em crianças e adolescentes, na faixa etária equivalente de 0 a 19 anos de idade, no período correspondente de jan/2013 a julho/2023. Método. Estudo epidemiológico, ecológico, realizado através da consulta do Departamento de Informática do Sistema Único de Saúde, por meio do Sistema de Internações Hospitalares, pela ferramenta Tabnet. Foram analisados os números de internações, óbitos e valor de serviços hospitalares, conforme regiões do Brasil, faixa etária, cor/raça e sexo, referentes ao período de jan/2013 a julho/2023. A coleta foi realizada em setembro/2023.  Resultados. No período analisado, ocorreram 10.401 internações. Foram registrados 205 óbitos. Relativo a valores dos serviços hospitalares, foram gastos R$ 29.606.189,56. Conclusão. O Nordeste destacou-se no quantitativo de internações e óbitos. Os menores de um ano de idade foram predominantes quanto aos números de internações, óbitos e valores de serviços hospitalares. Não houve prevalência quanto a cor/raça.
Violentar y matar: el tratamiento del secuestro y asesinato de Los Pujadas en medios periodísticos del 75, en Córdoba, Argentina
Authors: Rios Lucia
Published: November 2024

El presente artículo se centra en analizar formas en que la violencia fue representada en la prensa en el año 1975 en Córdoba, Argentina, focalizando particularmente en el asesinato de los miembros de la familia Pujadas y su repercusión en los medios periodísticos de la época. La tesis del artículo radica en que en el año 1975 se configuró en Córdoba un régimen de visibilidad mediante prácticas represivas que eran visibilizadas, espectacularizadas a nivel provincial atendiendo también en dicho proceso a la formación de identidades y a la configuración de moralidades específicas. Dicho régimen se configuró a partir de prácticas represivas ligadas a una exposición de la violencia que se expresó en el tratamiento de los cadáveres de personas asesinadas por la represión y en la amplificación de esas exposiciones presente en la cobertura de los medios de comunicación.
Antropologizar el ingreso, ingresar a la antropología
Authors: Caisso Lucía , Srur María Gabriela
Published: November 2024

En este escrito realizamos algunas reflexiones pedagógicas sobre el Curso de Nivelación de la Licenciatura en Antropología (Universidad Nacional de Córdoba) en el que nos desempeñamos como docentes desde hace más de una década. A partir del análisis de dos actividades realizadas en el marco de este espacio curricular abordamos dos temas que consideramos fundamentales para reflexionar en torno al ingreso de nuevos estudiantes al mundo universitario y al mundo de la antropología: la apropiación de la cultura escrita académica por parte de los y las estudiantes y el trabajo educativo en torno a la naturaleza heterogénea del estudiantado (en términos educativos, sociales y etarios, entre otros). Para indagar en ambas dimensiones recuperamos contribuciones teóricas propuestas en el marco de investigaciones educativas, socio-lingüísticas y antropológicas que nos permitieron repensar críticamente nuestra práctica docente para contribuir con el fortalecimiento pedagógico del ingreso de nuevos estudiantes al mundo de la antropología.
Enseñar antropología en “nuevos territorios”: la experiencia de la Licenciatura en Educación Intercultural de la Universidad Pedagógica Nacional (Argentina)
Authors: Gole Carla , Diez María Laura , Martinez Laura Victoria , Mombello Laura , Papazian Alexis
Published: November 2024

Este trabajo presenta una primera sistematización de nuestra experiencia de docencia e investigación en el marco de la Licenciatura en Educación Intercultural en la Universidad Pedagógica Nacional (Argentina), destinada a docentes en ejercicio. Recorremos los aportes de la antropología a dicha formación y explicitamos su relación con la definición del paradigma intercultural que asumimos, inscripto en la intersección de las políticas de identidad y el marco de derechos humanos. Buscamos profundizar en las prácticas de enseñanza y de investigación en la licenciatura analizando su territorialidad y los diálogos con las preocupaciones de docentes en actividad. En ese análisis, logramos sistematizar algunos de los desafíos y dilemas del trabajo sobre la diversidad en ámbitos educativos. Por último, reconstruimos parcialmente nuestras actividades de investigación, extensión, transferencia y comunicación pública de la ciencia para pensarlas en la coyuntura nacional argentina actual; allí planteamos algunas preocupaciones que atraviesan particularmente a nuestro ejercicio docente-investigativo.
Extending the horizon in cardiovascular risk prediction: A synergy of conventional predictors and spirometry data
Authors: Nevzorova V. A. , Shumatov V. B. , Priseko L. G. , Yurlova S. V. , Akhmedova E. B. , Koval’chuk V. K.
Published: November 2024

Aim. To assess a correlation between conventional cardiovascular risk factors and unprovoked pulmonary volumes and flows.Material and methods. The subjects (n = 153, median age 43 [32; 51] years) were divided into two groups depending on age. Questionnaires, anthropometry, biochemical blood analysis, spirometry without bronchodilation test, calculation of the lower limit of normal (LLN – low limit of normal) were carried out. Using the Mann – Whitney U-test, the two groups were compared quantitatively. When analyzing four-field conjugacy tables, a comparison was performed using the Pearson criterion χ2. The direction and closeness of the correlation were estimated using Spearman’s rank correlation coefficient. A predictive model was developed using the linear regression method. The differences were considered statistically significant at p < 0.05.Results. In group I (median age 29 [26; 33] years), reliable connections were established between the volume of forced expiratory volume in one second and high-sensitivity C-reactive protein (hsCRP); modified Tiffno index (m-TI) and total cholesterol, lowdensity lipoproteins, glucose. When analyzing the LLN data, reliable associations between m-IT and glucose (p = 0.004), hsCRP (p = 0.011) were obtained. In persons over 40 years of age with a smoking index of more than 10 packs/year, a relationship was found between a decrease in LLN m-TI and LLN of forced expiratory flow between 25 and 75% of forced vital capacity and an increase in creatinine (p < 0.001) and lipoprotein (a) (p = 0.03), respectively. Conclusion. There are differences in the relationship between the function of external respiration and laboratory indicators of cardiovascular risk in people before and after 40 years of age, which makes it possible to individualize the prediction of chronic non-communicable diseases.
Pharmacogenetic assessment of cytostatic therapy efficacy depending on the polymorphism of T1 and M1 glutathione-S-transferase genes in breast cancer patients
Authors: Gulian I. S. , Bystritskaya E. P. , Otstavnykh N. Y. , Gulyan G. S. , Hudchenko E. V. , Eliseeva E. V. , Isaeva M. P.
Published: November 2024

Aim. To study the effect of deletion polymorphism of the GST genes (GSTT1, GSTM1) on chemotherapy (CT) efficacy in women diagnosed with breast cancer (BC) in the Primorsky Krai. Materials and methods. The study involved 132 women with breast cancer aged 23 to 79 years (mean age 48 ± 13 years) who received chemotherapy treatment. The detection of deletion (null) genotypes of GSTM1 and GSTT1 was carried out using multiplex PCR followed by an analysis of the melting curves of the reaction products. Results. Relapse-free survival (RFS) of BC patients with the “null” GSTT1 genotype was statistically significantly higher (116.7 months (9.6 years) versus 75.8 months (6.2 years)) than in patients with the “normal” GSTT genotype. Thus, in the case of the GSTT1“null” genotype, the risk of disease relapse decreased by 2.4 times (HR = 0.418, CI = 0.191–0.915, p = 0.024). Similar to GSTT1, the DFS of patients with the GSTM1 null genotype increased from 72.7 months (6 years) to 76.1 months (6.3 years). At the same time, the risk of disease relapse in carriers of the “null” GSTM1 genotype decreased by 1.7 times (HR = 0.596, CI = 0.369–0.964, p = 0.033) compared with that in carriers of the “normal” GSTM1 genotype. Conclusions. Deletion polymorphism of the GSTT1 and GSTM1 genes has a significant impact on chemotherapy efficacy in breast cancer patients. Carriers of “null” genotypes demonstrated a higher RFS and a lower risk of developing disease relapse. Further research in this direction and validation of the data obtained may contribute to individualizing the treatment of breast cancer patients, optimizing chemotherapy regimens, and reducing the number of adverse events.
Treatment of patients with venous malformations of the maxillofacial region by sclerosing
Authors: Kamilov Sh. T.
Published: November 2024

Objective. To evaluate the efficacy of 3% sodium tetradecyl sulfate in the foam form in treating patients with venous malformations (VMs) of the maxillofacial region. Materials and methods. In total, 30 patients with VMs of the maxillofacial region were included in the study. The patients were divided into three groups: (1) patients with a small VM size of up to 2 cm in diameter; (2) patients with an average VM size from 2 to 6 cm in diameter; (3) patients with a large VM size above 6 cm in diameter. In the treatment of patients, a foam form of 3% sodium tetradecyl sulfate was used. Results. All patients were treated without intraoperative and postoperative bleeding. According to the results of the study, large VMs decreased in size by an average of 49.7%, medium malformations decreased by an average of 68.1%, while small malformations decreased by 69.6%.Conclusion. Sclerosing of venous malformations of the maxillofacial region with a foam form of 3% sodium tetradecyl sulfate is an effective, affordable, and safe treatment method.
Epidemiology of HIV infection in penal system institutions
Authors: Vostroknutov M. E. , Sterlikov S. A. , Dyuzheva E. V. , Ponomarev S. B.
Published: November 2024

Aim. To assess the medical and statistical indicators of the health status of persons with the disease caused by the human immunodeficiency virus (HIV), among suspects, accused, and convicts held in institutions of the penal system. To develop proposals for improving work in the field of countering the spread of HIV infections. Materials and methods. The structure and dynamics of morbidity and mortality from HIV infection in penal institutions from 2014 to 2022 was analyzed using official statistical data. Calculations were carried out using MS Excel application packages and the R software environment version 3.6.2.Results. The peak HIV incidence in penal system institutions was recorded in 2015, followed by its gradual decrease by 2020. HIV mortality decreased by 52.1% since 2014, amounting to 84.6 per 100,000 people in 2022. The mortality rate of people living with HIV (PLHIV) decreased by 61.5% in 2014. This dynamics showed a decreasing trend starting from 2015. The antiretroviral therapy coverage in this group of patients reached a maximum value of 94.5% by 2022. Conclusions. The HIV mortality and mortality rates during the study period show a downward trend. The antiretroviral therapy coverage in 2022 reached a historic maximum. However, this does not exclude the low adherence of patients to treatment, which indicates the need to develop new methods of sanitary education and therapeutic and preventive work in penal system institutions.
VCO AND ALOE VERA TO CURE DIAPER RASH IN BABIES 0-2 YEARS OLD
Authors: Mei Lia Nindya Zulis Windyarti  , Prestian Yuni Fitri , Wulandari Dyah Ayu
Published: November 2024

Background: Diaper rash is dermatitis due to irritation in the form of skin manifestations caused by various things. In Indonesia, as many as 22 million toddlers in Indonesia, around 1/3 of the number of these babies experience diaper rash. Treatment of diaper rash can be done with non-pharmacological therapy, namely by using Aloe vera because it has a therapeutic effect as an anti-inflammatory and antimicrobial and has safety in dealing with diaper rash because it contains alpha-bisabolol. Another alternative that can be used to prevent or treat diaper rash is coconut oil (coconut oil) for skin health and anti-microbial. Objective: To determine the effectiveness of VCO and Aloe vera in accelerating the healing of diaper rash in infants 0-2 years. Research Methods: Type of quantitative research with a quasi-experimental approach and a pretest-posttest design. The population in this study were infants aged 0-2 years who had diaper rash. Research Results: Based on the results of the Mann-Whitney test, the p-value of the Mann-Whitney test was obtained, respectively above 0.05 (p>0.05), namely 0.658; 0.593; and 0.483. This insignificant difference can also be interpreted that Aloe vera and VCO have relatively similar effectiveness in healing diaper rash inflammation. Conclusion Aloe vera and VCO have the same effectiveness in healing inflammatory diaper rash.
ТЕОРЕТИЧЕСКИЕ АСПЕКТЫ ЭФФЕКТИВНОСТИСЕАНСА АРТ-ТЕРАПИИ
Authors: С.Р. Николаева , В.А. Демарева
Published: November 2024

В данной статье рассматривается теоретический аспект эффективности сеанса арт-терапии. Статья подчеркивает важность комплексного подхода к оценке арт-терапии, обращая внимание на значимость взаимодействия между терапевтом и клиентом, а также на необходимость учета индивидуальных характеристик участников терапии. Результаты теоретического исследования могут быть полезны как практикующим специалистам, стремящимся повысить качество своей работы, так и ученым, занимающимся изучением методов психотерапии. Это исследование призвано углубить понимание арт-терапии как уникального инструмента в арсенале психотерапевта и способствовать дальнейшему развитию данной области, а также обозначить необходимость психофизиологических исследований для более глубокого понимания эффекта арт-терапии для человека.

This article discusses the theoretical aspect of the effectiveness of an art therapy session. The article emphasizes the importance of a comprehensive approach to the evaluation of art therapy, drawing attention to the significance of the interaction between the therapist and client, as well as the need to take into account the individual characteristics of therapy participants. The results of the theoretical study may be useful to practitioners seeking to improve the quality of their work as well as to scholars studying psychotherapy methods. This study is intended to deepen the understanding of art therapy as a unique tool in the psychotherapist's arsenal and contribute to the further development of the field, as well as to outline the need for psychophysiological research to better understand the effects of art therapy on the individual.
ДУХОВНОСТЬ ЧЕЛОВЕКА СКВОЗЬ ПРИЗМУ ПСИХОФИЗИОЛОГИИ
Authors: Р.Р. Сулейманова
Published: November 2024

В статье рассмотрена связь между духовностью и психофизиологией человека. Дан анализ влиянию духовных практик на физическое и психическое здоровье, а также описана роль духовности в развитии личности.

The article examines the connection between spirituality and human psychophysiology. It analyzes the influence of spiritual practices on physical and mental health, and describes the role of spirituality in personality development.
РОЛЬ ТЕЛЕСНО - ОРИЕТИРОВАННОЙ ТЕРАПИИ В ВОСТАНОВЛЕНИИ ПОСТСТРЕССА
Authors: Л.Н. Смелышева , А.И. Драгилева
Published: November 2024

Оценено влияние телесно-ориентированной терапии (ТОТ) на восстановление пациентов с постстрессорными расстройствами. Показатели вариабельности сердечного ритма (ВСР) до и после терапии продемонстрировали значительные изменения в уровнях стресса, активности симпатической и парасимпатической нервных систем, а также общего объема энергии.

The influence of body-oriented therapy (BOT) on the recovery of patients with post-traumatic stress disorders was assessed. Heart rate variability (HRV) indicators before and after therapy demonstrated significant changes in stress levels, sympathetic and parasympathetic nervous system activity, as well as overall energy levels.
ДИНАМИКА ЭМОЦИОНАЛЬНОГО СОСТОЯНИЯ ЧЕЛОВЕКА ДО И ПОСЛЕ ТРЕНИНГОВ В ВИРТУАЛЬНОЙ РЕАЛЬНОСТИ
Authors: М.М.А. Аранива , А.Б. Демарев , В.А. Демарева
Published: November 2024

В данном исследовании изучается динамика эмоционального состояния человека до и после тренингов в среде виртуальной реальности (VR). В исследовании применяется смешанный подход, в котором используются как психологические, так и физиологические данные, чтобы получить полную картину эмоциональных изменений. Участники (11 студентов) прошли серию из пяти VR-тренингов, при этом их эмоциональное состояние оценивалось до и после тренинга. Предварительные результаты свидетельствуют о том, что VR-тренинги могут способствовать снижению уровня тревожности и улучшению общего эмоционального состояния.

This study examines the dynamics of a person's emotional state before and after trainings in virtual reality (VR). The study uses a mixed approach that combines psychological and physiological data to get a complete picture of emotional changes. The participants, 11 undergraduate students, completed a series of five VR trainings, and their emotional state was assessed both before and after the training. Preliminary results suggest that VR trainings can help reduce anxiety levels and improve overall emotional well-being. Key words: virtual reality, emotional state, training.
ДИНАМИКА ПСИХОЛОГИЧЕСКОГО СТАТУСА СТУДЕНТОВ ПРИ ОБУЧЕНИИ В МЕДИЦИНСКОМ ВУЗЕ
Authors: Ю.В. Кашина , И.Л. Чередник , В.М. Покровский , В.В. Полищук , А.В. Шаханова
Published: November 2024

Цель исследования выявить динамику показателей психологического статуса студентов при обучении в медицинском вузе. Среди студентов-медиков второго и пятого курсов Кубанского государственного медицинского университета к концу учебного года увеличивалось количество человек с высоким уровнем тревожности (на 5,5%); со средним (на 3,2%) и повышенным (на 2,8%) уровнями агрессии; с легким (на 12,1%) и умеренным (на 18,4%) уровнями депрессии. Также наблюдалась отрицательная динамика эффективности работы, степени врабатываемости, психической устойчивости, самочувствия, активности, настроения на фоне снижения индекса регуляторно-адаптивного статуса, который имел более низкие значения в группах с высокой тревожностью, повышенной агрессией, умеренным уровнем депрессии, особенно в конце учебного года.

The study objective was to study the dynamics of students’ psychological status indicators during their studies at a medical university. By the end of the academic year, medical Years second and fifth students revealed the enhanced (by 5.5%), with medium (by 3.2%) and increased (by 2.8%) levels of aggression; with mild (12.1%) and moderate (18.4%) levels of depression. Against the background of a decreased index of the regulatory and adaptive status, there was a negative dynamics of the effectiveness of workability, mental stability, well-being, activity, and mood. Lower index of the regulatory and adaptive status index values were observed in groups with a high personal anxiety, elevated aggression, and moderate depression levels, especially at the end of the school year.
ХРОНИЧЕСКИЙ СТРЕСС СКУЧЕННОСТИ У КРЫС. НЕКОТОРЫЕ ПРИЗНАКИ АДАПТАЦИИ ОРГАНИЗМА К ДЛИТЕЛЬНОМУ ОГРАНИЧЕНИЮ ЖИЗНЕННОГО ПРОСТРАНСТВА
Authors: А.А. Потехина , Н.А. Логинова , Е.В. Лосева
Published: November 2024

Социальный стресс перенаселенности в человеческом обществе приводит к различным негативным последствиям для организма. Адекватная модель длительной перенаселенности в замкнутом пространстве – долговременная скученность (СК) грызунов в виварии. Задачи работы состояли в том, чтобы при 6-и месячной СК у крыс 1) выявить особенности поведения в тестах на тревожность и депрессию; 2) определить массу тела и ряда органов, входящих в стресс-систему. При СК у крыс наблюдалось умеренно тревожное и выраженное депрессивно-подобное поведение, однако признаков ангедонии у них не было; макроскопических изменений внутренних органов не выявлено, но масса тела была на 25,7% меньше, чем в контроле, и имели место характерные для хронических стрессов изменения массы тимуса, селезенки, надпочечников. Скученные крысы спали вертикально носом вверх у стенки клетки. Предполагается, что депрессивно-подобное поведение, уменьшение массы тела и новая поза для сна у крыс при длительной СК могут говорить не только о патологических процессах, но и об адаптации организма к условиям скученного содержания.

The social stress of overcrowding in human society leads to various negative consequences for the organism. An acceptable model of long-term overcrowding is long-term crowding of rodents. The objectives of the work were to 1) identify characteristics of behavior in tests for anxiety and depression during 6-month crowding in rats; 2) determine the weight of the body and a number of organs included in the stress-system. The crowded rats demonstrated moderately anxious and expressed depressive-like behavior, but there were no signs of anhedonia; macroscopic changes of internal organs were not revealed, but body weight was 25,7% less than in the control, and there were changes in the weight of thymus, spleen, and adrenal glands typically for chronic stress. The crowded rats slept vertically with their noses up. It is assumed that depressive-like behavior, decrease in body weight and new sleeping posture in rats with long-term crowding may be not only pathological processes, but also may be an adaptation of the organism to the crowding.
ДИНАМИКА ВАРИАБЕЛЬНОСТИ РИТМА СЕРДЦА ПРИ КОГНИТИВНОЙ НАГРУЗКЕ ДО И ПОСЛЕ АЭРОБНЫХ УПРАЖНЕНИЙ: ПИЛОТНЫЙ ЭКСПЕРИМЕНТ
Authors: С.О. Олауво , В.А. Демарева
Published: November 2024

Статья посвящена исследованию динамики вариабельности ритма сердца (ВРС) во время выполнения тестов на рабочую память до и после аэробных упражнений у 10 студентов. Оценивались временные и спектральные показатели ВРС при выполнении задачи «n-назад» до и после 15-минутной сессии аэробных упражнений. Результаты показали значительное снижение большинства метрик ВРС после аэробных упражнений, что указывает на увеличение симпатической активности и снижение парасимпатической модуляции. Эти изменения подтверждают, что аэробные упражнения влияют на вегетативную регуляцию, что также может быть опосредовано влиянием когнитивной нагрузки. Необходимо продолжение данного исследования для сопоставления успешности решения задач на рабочую память и динамики ВРС, а также привлечение контрольной и экспериментальной групп для оценки влияния аэробных упражнений на улучшение показателей рабочей памяти.

The article is dedicated to investigating the dynamics of heart rate variability (HRV) during working memory tests before and after aerobic exercise in 10 students. Time and frequency domain HRV metrics were assessed during the n-back task before and after a 15-minute aerobic exercise session. The results showed a significant decrease in most HRV metrics after aerobic exercise, indicating increased sympathetic activity and reduced parasympathetic modulation. These changes confirm that aerobic exercise affects autonomic regulation, which may also be influenced by cognitive load. Further research is needed to compare working memory task performance and HRV dynamics, as well as to involve control and experimental groups to evaluate the impact of aerobic exercise on improving working memory performance.
Pemerolehan Bahasa pada Anak Penyandang "Down Syndrome"
Authors: Muldawati* Muldawati , Rosidin Odien , Juansah Dase Erwin
Published: November 2024

This article analyzes, classifies and explains the acquisition of speech in children with Down syndrome, both reduction and substitution. Qualitative descriptive research method, data collection techniques: listening, taking notes, interviews and documentation. The results of speech reduction research for people with Down syndrome experienced difficulties with vowels [e] and vowels [i]. Consonant difficulties include the bilabial consonant phoneme [b] [m] [p], the alveolar consonant phoneme [l] [r] [n] [s], the glottal consonant phoneme [h], and the dental consonant phoneme [t]. Meanwhile, in speech substitution, 15 phonemes are substituted, namely [l] ? [y], [l] ? [r], [j] ? [s], [d] ? [i], [k] ? [ t], [g] ? [h], [s] ? [w], [b] ? [w], [b] ? [y], [r] ? [y], [t] ? [w] , [t] ? [?], [?] ? [g], [n] ? [?], [?] ? [n].Keywords: down syndrome; psycholinguistics; speechAbstrak:Artikel ini menganalisis, mengklasifikasikan, menjelaskan pemerolehan ujaran pada anak down syndrome baik reduksi maupun substitusinya. Metode penelitian deskriptif kualitatif, teknik pengumpulan data simak, catat, wawancara, dan dokumentasi. Hasil penelitian reduksi ujaran penyandang down syndrome mengalami kesulitan vokal [e] dan vokal [i]. Kesulitan konsonan yaitu fonem konsonan bilabial [b] [m] [p], fonem konsonan alveolar [l] [r] [n] [s], fonem konsonan glotal [h], dan fonem konsonan dental [t]. Sedangkan pada substitusi ujaran  fonem yang mengalami substitusi sebanyak 15 fonem, yaitu [l] ? [y], [l] ? [r], [j] ? [s], [d] ? [i], [k] ? [t], [g] ? [h], [s] ? [w], [b] ? [w], [b] ? [y], [r] ? [y], [t] ? [w], [t] ? [?], [?] ? [g], [n] ? [?], [?] ? [n].Kata kunci: down syndrome; psikolinguistik; ujaran