bluuebunny/crossref_metadata_2025 huggingface dataset:
Nanosilica polyamidoamine dendrimers for enhanced direct air CO2 capture
Authors: Kulkarni Vaishnavi , Parthiban Jayashree , Singh Sanjay Kumar
Published: August 2024

Nanosilica polyamidoamine dendrimers showed an impressive CO2 uptake in humid indoor air with superior adsorption–desorption cycles and low regeneration temperature for efficient CO2 recovery to utilize it for formate and CaCO3 synthesis.
A quasi-zero-strain layered Nb4P2S21 cathode for high-energy solid-state polymer Na–metal batteries
Authors: Tu Xueyang , Peng Baixin , Wang Xue , Wang Xue , Zhang Shaoning , Fang Yuqiang , Dong Wujie , Le Jiabo , Hu Keyan , Huang Fuqiang
Published: August 2024

A quasi-zero strain mechanism for high-capacity sodium storage of Nb4P2S21 revealed by in situ XRD and density functional theory (DFT) calculations.
Boosting the oxygen evolution reaction via the reconstruction of an M(OH)x/Fe3O4 catalyst
Authors: Wang Xiaoqu , Wang Limin , Liu Yongchun , Devasenathipathy Rajkumar , Liu Li , Huang Qiulan , Huang Dujuan , Fan Youjun , Chen Du-Hong , Chen Wei
Published: August 2024

The M(OH)x/Fe3O4/IF catalyst exhibited low overpotential of 214 mV for the OER at current density of 50 mA cm−2. The in situ Raman spectra revealed that the reconstruction of M(OH)x/Fe3O4/IF boosted the OER activity.
Asymmetric synthesis of acyclic N–N axially chiral indole compounds via catalytic N-acylation reaction
Authors: Huang Zilu , Xu Yunyi , Lin Wei , Qian Rui , Zhang Wei , Li Xin
Published: August 2024

Herein, we present an enantioselective synthesis of N-aminoindoles bearing a N–N axis via chiral isothiourea catalyzed asymmetric N-acylation. Notably, some of the products exhibited promising cytotoxicity activities against some cancer cell lines.
Smart hydrogel composite for microenvironmental humidity regulation in cigar storage
Authors: Ji Xiaoying , Li Xiaopeng , Liu Juan , Wu Di , Liang Qianqian , Zhu Beibei , Fang Wanjiao , Qiu Shirui , Zhang Qianying , Li Dongliang , Zhao Lijuan , Wang Yi
Published: August 2024

This paper presents a novel PAS-PDMS composite inspired by skin, which maintains stable humidity for over 20 days in cigar storage. It features superior mechanical properties, 84% light transmittance, and effectively preserves valuable plant leaves.
A study on thermal behaviour of thermal barrier coating: investigation of particle size, YSZ/polysilazane, time and temperature curing effect
Authors: Widyastuti  , Zulfa Liyana Labiba , Rizaldi Wafiq Azhar , Azhar Jauhari , Safrida Ninik , Pratama Azzah Dyah , Wahyuono Ruri Agung , Sulistijono  , Fajarin Rindang , Hakim Arif Nur
Published: August 2024

Thermal conductivity and adhesion strength effects were studied for thermal barrier coatings (TBCs) with different particle sizes, YSZ content, time, and temperature curing.
A phytic acid-based CoMn bimetallic metal–organic aerogel (PA–CoMn-1 : x : 2 − x) as a modifier for electrochemical detection of non-steroidal anti-inflammatory drug 4-acetaminophenol
Authors: Guo Huijun , Qi Yifei , Wang Guoxin , Zhang Yue , Li Siqi , Tan Boyu
Published: August 2024

Metal phosphides and phosphate-based materials have received significant attention due to their high electrocatalytic activity, adjustable structure composition and stability.
Coumarin–amino acid hybrids as promising anticancer agents: design, synthesis, docking studies and CK2 inhibition
Authors: El-Etrawy Abd-Allah S. , Ramadan Ahmad , Sherbiny Farag F. , Zeid I. F. , Abdel-Rahman A. A.-H. , Hawata Mohamed A.
Published: August 2024

A new series of amino acid derivatives linked to coumarin has been synthesized as CK2 inhibitors. Compound 7c outperforms doxorubicin in cell lines, while compound 5b shows superior CK2 inhibition compared to roscovetine.
Hydrogen production by aqueous phase reforming of methanol over stable C-modified NiMgAl hydrotalcite catalyst
Authors: Huang Yuankai , Huang Jiahao , Shu Riyang , Lei Libin , Song Qingbin , Tian Zhipeng , Wang Chao , Chen Ying
Published: August 2024

Enhanced methanol conversion and hydrogen yield are achieved over carbon modified hydrotalcite catalyst with high stability.
Quantifying near-symmetric molecular distortion using symmetry-coordinate structural decomposition
Authors: Kingsbury Christopher J. , Senge Mathias O.
Published: August 2024

A new method for analyzing crystal structures of molecules distorted from their regular shape separates atom movements into symmetry modes so that molecular conformation of functional materials can be quantified and compared easily across databases.
Palladium-catalyzed decarboxylative (4 + 3) cycloadditions of bicyclobutanes with 2-alkylidenetrimethylene carbonates for the synthesis of 2-oxabicyclo[4.1.1]octanes
Authors: Gao Xin-Yu , Tang Lei , Zhang Xu , Feng Jian-Jun
Published: August 2024

A novel palladium-catalyzed strategy was employed to achieve higher-order (4 + 3) cycloadditions of bicyclobutanes with various 2-alkylidenetrimethylene carbonates to synthesize 2-oxabicyclo[4.1.1]octanes.
Understanding the catalytic performances of metal-doped Ta2O5 catalysts for acidic oxygen evolution reaction with computations
Authors: Han Congcong , Wang Tao
Published: August 2024

Ta2O5 doped by Ir, Ru, or Nb was computationally predicted to show reasonably good performance for acidic oxygen evolution reaction.
Shear annealing of a self-interacting sheet
Authors: Funkenbusch William T. , Silmore Kevin S. , Doyle Patrick S.
Published: August 2024

Applying simple time-dependent shear flow protocols to simulations of semi-flexible, self-interacting, athermal sheets allows for tuning of the shapes and alignments of suspensions of these sheets.
Shear-controlled composite cathodes for all-solid-state batteries combined synergistically with stereology-driven image analysis
Authors: Jeong Hyeseong , Hwang Heesu , Cho Jeong-Won , Shin Dongwook , Lee Jong-Ho , Shin Sung Soo , Hwang Jin-Ha , Kim Hyoungchul
Published: August 2024

Multiple optimization of composite cathodes in all-solid-state batteries is demonstrated by applying controlled shear pressure and stereology-driven image analysis.
In situ cascade steric stabilization of poly(ionic liquid) mediated hexagonal nickel hydroxide morphogenesis for high-performance flexible supercapacitors
Authors: Narayanan Abhishek , Naik Nagaraj S. , Kapse Samadhan , Thapa Ranjit , Balakrishna R. Geetha , Rout Chandra Sekhar , Padaki Mahesh
Published: August 2024

Poly(ionic liquid) mediated hexagonal nickel hydroxide crystals offer improved structural integrity for flexible supercapacitor applications.
Electro-oxidation of alcohols over electrochemically activated nickel alloys for energy-saving hydrogen production
Authors: Ni Ming , Tan Minyuan , Luo Kang , Jiang Daochuan , Yuan Yupeng , Zhu Chuhong , Du Haiwei , Ren Hangjuan
Published: August 2024

High-valence metal species generated via in situ electrochemical activation effectively enhance the adsorption of small organic molecules on the alloy surface.
Insights into hydroelectric nanogenerators: numerical simulation and experimental verification
Authors: Su Hongli , Nilghaz Azadeh , Tang Kunning , Liu Dan , Zhao Shuaifei , Tian Junfei , Bu Yiming , Li Jingliang
Published: August 2024

Good simulation! The simulation of the output electrical performance of hydroelectric nanogenerators is coupled with the electrostatic and dynamic electrical processes to match the experimental results.
Complementary X-ray and neutron imaging of water electrolysers for green hydrogen production
Authors: Altus Sebastian J. , Inkson Beverley J. , Hack Jennifer
Published: August 2024

This perspective discusses the current status and future needs for the use of X-ray and neutron imaging as complementary methods for helping solve key challenges facing electrolyser materials.
Improved ammonia production using Cu2O@poly-carbazole electrocatalysts in the electrochemical reduction of molecular nitrogen and nitrogen oxoanions
Authors: Herrán Luis , Veliz-Silva Diego F. , Poblete Colin , Leiva Elías , Honores Jessica , Landaeta Esteban , Sancy Mamié , Río Rodrigo del , Sáez-Navarrete César , Dalchiele Enrique , Isaacs Mauricio
Published: August 2024

In this work, a Cu2O@PCz electrode is proposed for the electrocatalytic production of ammonia reducing nitrogen and nitrogen oxoanions. This electrode takes advantage of the catalytic properties of Cu2O together with the stabilization provided by polycarbazole (PCz).
Understanding water-gas shift reaction mechanisms at palladium–ceria interfaces using in situ SERS coupled with online mass spectrometry
Authors: Wei Di-Ye , Zhang Ge , Wang Hong-Jia , Zheng Qing-Na , Tian Jing-Hua , Zhang Hua , Li Jian-Feng
Published: August 2024

In situ SERS coupled with online mass spectrometry reveals that CO adsorbed on Pd can efficiently react with oxygen species formed from water dissociation at the Ce3+ sites nearby, thus leading to improved performance at the Pd–CeO2 interfaces.
Simple preparation of 1D hierarchical magnetic CNTs/hollow porous macroscopic carbon fiber composites for efficient microwave absorption
Authors: Yang Minghang , Deng Yu , Zhang Mingguang , Zhou Shuaining , Liu Cheng , Jian Xigao , Chen Yousi
Published: August 2024

1D self-supporting CNT-loaded hierarchical hollow porous carbon fibers with excellent microwave absorption properties were prepared using low-cost polypropylene fibers as precursors.
Designing strategies for high-redox-potential conjugated carbonyl organic cathodes in lithium- and sodium-ion batteries
Authors: Liu Zhaoli , Meng Xiangyu , Cui Fengchao , Zhu Guangshan
Published: August 2024

Several strategies were introduced to enhance redox potential of conjugated carbonyl organic cathodes. The intrinsic factors contributing to the elevation of redox potentials and the underlying mechanisms of lithium/sodium storage were elucidated.
Reinforcing an interfacial molecular dam through a multifunctional organic electrolyte additive for stable Zn anodes
Authors: Lin Zhenxin , Zhang Yufei , Lin Xiaoting , Ding Hanlin , Ye Minghui , Wen Zhipeng , Tang Yongchao , Liu Xiaoqing , Li Cheng Chao
Published: August 2024

Triazole obstructs water induced corrosion and modulates Zn ion flux through its hydrophobic and zincophilic properties.
Enhanced energy efficiency of aqueous organic redox flow batteries: carbon-based heterostructure electrodes guided by an interface engineering strategy
Authors: Yang Xiaohui , Li Xiong , Xu Tongle , Cai Hongyun , Zhao Can , Song Na , Ding Peng
Published: August 2024

In this work, the TEMPTMA/MV AORFB with an rGOCF-3 heterostructure electrode demonstrated remarkable improvement in energy efficiency of 80.05% at the current density of 50 mA cm−2 for 200 cycles.
2D conductive metal–organic frameworks for NO electrochemical reduction: a first-principles study
Authors: Chen Xing , Zhu Xiangyu , Xia Zhiyuan , Qian Shiting , Zhou Yanan , Luo Qiquan , Yang Jinlong
Published: August 2024

Designing flexible single-atom catalysts with tunable single-atom centers and coordination environments is crucial for highly active and selective electrochemical catalysis.
Soft nanoparticles as antimicrobial agents and carriers of microbiocides for enhanced inhibition activity
Authors: Yong Hui Wen , Ojagh Seyed Mohammad Amin , Théberge-Julien Gabriel , Castellanos Laura Sofia Reyes , Tebbji Faiza , van de Ven Theo G. M. , Sellam Adnane , Rhéaume Éric , Tardif Jean-Claude , Kakkar Ashok
Published: August 2024

Antibiotic resistance continues to pose significant health challenges. Dual action soft nanoparticles provide an advantageous platform to address it.
Impact of Hearing Aid Processing Delay on Stop Consonant Voicing Perception in Open Fittings
Authors: Korhonen Petri , Slugocki Christopher , Kuk Francis , Peeters Heidi
Published: August 2024

Purpose:

Hearing aid (HA) processing delay results in asynchronous overlap of the input sound and the delayed amplified sound at the eardrum in open-ear fittings. This may distort the temporal cues used for stop-consonant voicing distinctions. The current study evaluated the impact of HA processing delay on voiced–voiceless categorization of syllable initial consonants /d/ and /t/ for a range of voice onset times (VOTs).

Method:

Nineteen older listeners (
M
age
= 73 years) with mild–moderate sensorineural hearing loss participated. All listeners performed the voiced–voiceless categorization task in double-blind within-subjects design. Thirteen stimulus tokens along the /di:/ - /ti:/ continuum were created by varying VOTs. Stimuli were then processed using an HA simulator, which simulated the overall sound pressure levels measured at the eardrum in open-ear fittings with four processing delay times (0, 0.5, 5, and 8 ms). Individualized stimuli were generated for each listener based on their audiogram and presented via calibrated ear inserts at the most comfortable listening level. Performance across all VOT intervals was fitted with psychometric functions, which were then used to estimate the voiced–voiceless crossover point and the slope parameter for each simulated delay condition.

Results:

The crossover point along the voiced–voiceless continuum shifted systematically with increased processing delay toward voiced /di:/ over unvoiced /ti:/ percepts. The shift in the crossover point between the 0-ms reference condition and the 8-ms processing delay condition corresponded to 5.8 ms of change in VOT. The 8-ms processing delay condition resulted in significantly shallower categorization slopes compared to the 0- and 0.5-ms delay conditions.

Conclusions:

Temporal distortions created by HA processing delay in open-ear fittings impacted voicing perception of syllable initial stop-consonant stimuli near the voiced–voiceless crossover point. Short HA processing delay should be considered for open-ear fittings to preserve the natural VOT cues used for voicing detection.
Stuttering Impact and Patient Trust in Indian Health Care: A Cross-Sectional Study
Authors: Mallipeddi Nathan V. , Aulov Sivan , Perez Hector R.
Published: August 2024

Purpose:

This study aims to determine the relationship between (a) stuttering impact and trust in the health care system and (b) stuttering impact and trust in physicians among persons who stutter in India.

Method:

This quantitative study utilized cross-sectional electronic surveys to assess the experiences of 118 adults who stutter in India. The surveys queried (a) stuttering impact, (b) trust in the health care system, and (c) trust in physicians.

Results:

Stuttering impact is strongly negatively associated with trust in the health care system (
r
= −.940,
p
≤ .0001,
R
2
= .885) and strongly negatively associated with trust in physicians (
r
= −.941,
p
≤ .0001,
R
2
= .885). Controlling for age, gender, and income does not affect these relationships.

Conclusions:

The strongly significant associations found in this study between stuttering impact and trust call attention to how interrelated stuttering experiences are with trust in health care. Speech-language pathologists around the globe may wish to discuss how stuttering might affect health care experiences with their clients who stutter to build rapport, to advocate for people who stutter, and to better support their health professional colleagues.
Intracranial hematoma segmentation on head CT based on multiscale convolutional neural network and transformer
Authors: Li Guangyu , Gao Kai , Liu Changlong , Li Shanze
Published: August 2024

Intracranial hematoma, a severe brain injury caused by trauma or cerebrovascular disease, can result in blood accumulation and compression of brain tissue. Untreated cases can cause headaches, impaired consciousness, and even brain tissue damage or death. Therefore, early and accurate diagnosis is crucial. Traditional segmentation methods require physicians with extensive clinical experience and expertise to manually mark out the hematoma region, but for hematoma cases with irregular shapes and uneven grey levels, this process is cumbersome, and the segmentation results are not good. Existing deep learning‐based methods are more likely to perform binary segmentation, considering all hematomas as a class and segmenting them, but this segmentation cannot capture more detailed information and lacks the analysis of different types of hematomas. To address these problems, an ICH segmentation network combining CNN and Transformer Encoder is proposed for accurate segmentation of different types of hematomas. The network incorporated edge information and long‐range context into the segmentation process. Experimental results using the CQ500 dataset demonstrate comparable performance to existing methods, with mIoU (0.8705), TPR (0.9273), mAP (0.9300), and DSC (0.9286) as the best metrics achieved by this paper's method.
Face super resolution with a high frequency highway
Authors: Zeng Dan , Jiang Wen , Yan Xiao , Fu Weibao , Shen Qiaomu , Veldhuis Raymond , Tang Bo
Published: August 2024

Face shape priors such as landmarks, heatmaps, and parsing maps are widely used to improve face super resolution (SR). It is observed that face priors provide locations of high‐frequency details in key facial areas such as the eyes and mouth. However, existing methods fail to effectively exploit the high‐frequency information by using the priors as either constraints or inputs. This paper proposes a novel high frequency highway () framework to better utilize prior information for face SR, which dynamically decomposes the final SR face into a coarse SR face and a high frequency (HF) face. The coarse SR face is reconstructed from a low‐resolution face via a texture branch, using only pixel‐wise reconstruction loss. Meanwhile, the HF face is directly generated from face priors via an HF branch that employs the proposed inception–hourglass model. As a result, allows the face priors to have a direct impact on the SR face by adding the outputs of both branches as the final result and provides an extra face editing function. Extensive experiments show that significantly outperforms state‐of‐the‐art face SR methods, is general for different texture branch models and face priors, and is robust to dataset mismatch and pose variations.
Compact linear‐phase bandpass filters with notched frequency response employing eighth‐mode substrate integrated waveguide and dual‐mode microstrip line structure
Authors: Yang Hang , Wang Xiang , Yang Xian‐Long , Zhu Xiao‐Wei , Wu Wen
Published: August 2024

A series of fourth‐order bandpass filters (BPFs) with compact footprints, broad bandwidth, high selectivity, linear phase and notched response are proposed. The sketch of these BPFs is in accordance with the combination of the eighth‐mode substrate integrated waveguide (EMSIW) and dual‐mode microstrip line (DMML) resonators. The DMML resonator is constructed by means of metallic via‐holes and pad in the double‐layered structures. Among them, the DMML resonator can provide two transmission poles. Besides, the cross coupling is introduced through the vertical slot or fan‐shaped aperture in the dual‐layered substrates. The coupling schemes of the proposed BPFs can introduce two transmission zeros in the vicinity of operating passband, and the coupled scheme also exhibits a relatively flat in‐band group delay. Notched frequency responses have been obtained by exploiting the U‐shaped resonator and folded‐ring resonator embedded with the mixed EMSIW and DMML BPFs. To validate the conceptual design, the proposed BPFs are simulated, fabricated and measured. Both the simulation and measurement have reached to a satisfactory agreement.
Model predictive control of 3L‐NPC inverter to enhance fault ride through capability under unbalanced grid conditions
Authors: Smith Cameron , Gargoom Ameen , Arif M. T. , Haque Md. Enamul
Published: August 2024

Unbalanced voltages are becoming increasingly common in distribution networks due to the growing integrations of distributed renewable energy resources as well as large loads such as electric vehicle chargers. Such unbalanced voltages introduce significant control challenges as they produce ripples in the controlling signals, impacting the operation of inverters during the unbalanced conditions. Therefore, this paper proposes a controlling algorithm for three‐level inverters aimed at suppressing these ripples on controlling signals; improving the overall performance of inverters, and consequently enhancing the fault ride‐through capability under unbalanced conditions and faults. The proposed controlling algorithm enables inverters to operate in either a balanced current output mode or a suppressed‐ripple active power output mode, depending on the specific event scenario and demands from the grid operators. Current harmonics are suppressed even under severe faults. For improving the voltage balance on the DC capacitors in three‐level inverters, an enhanced method of neutral point current prediction is presented. The proposed method ensures higher balancing accuracy through the use of weighted switching costs, avoiding the requirement of a balancing controller or current extrapolation. Simulation and experimental results demonstrate the effectiveness of the proposed controller for reliable grid operation.
Discrete model and non‐linear characteristics analysis of magnetic coupled resonant wireless power transfer system with constant power load
Authors: Huang Liangyu
Published: August 2024

Magnetically coupled resonant wireless power transfer (MCR‐WPT) system with constant power load (CPL), finds extensive applications in military, industrial, and medical treatment. However, this system can easily exhibit complex non‐linear behaviors under certain parameter conditions due to the influences of constant power loads, switching devices, and feedback controllers. These behaviors limit the effectiveness of controllers and reduce the efficiency and stability of the system. It is necessary to study the non‐linear characteristics of the MCR‐WPT system with CPL. The stroboscopic discrete mapping of the MCR‐WPT system with CPL is established. Then the system's non‐linear dynamics are analyzed theoretically using a bifurcation diagram, the maximal Floquet multipliers, and the maximal Lyapunov exponent spectrum obtained from the proposed discrete mapping. The results show that the MCR‐WPT system with CPL will exhibit rich non‐linear dynamics with the variation of the power of CPL, such as cyclic fold bifurcation, Neimark–Scaker bifurcation, border collision bifurcations, chaos, etc. The excellent alignment of experimental and theoretical outcomes in corresponding states confirms the accuracy of the proposed discrete mapping and the nonlinear analysis of the system. The results of this study can provide a reference for selecting parameters for an actual MCR‐WPT system with CPL.
Prise en charge de la douleur arthrosique chronique :
que faire lorsque les AINS ne suffisent plus ?
Authors: Junot Stéphane
Published: August 2024

La douleur arthrosique présente une origine multifactorielle, son traitement est donc complexe. Le traitement à base d'anti-inflammatoires non stéroïdien constitue le traitement médical de base de cette affection, mais il peut s'avérer moins efficace ou mal toléré, et nécessiter le recours à d'autres traitements complémentaires ou substitutifs.

Le paracétamol (uniquement chez le chien, contre-indiqué chez le chat), certains antiépileptiques (gabapentine) et antiparkinsoniens (amantadine), des antidépresseurs tricycliques ainsi que des morphiniques faible (tramadol) sont des traitements adjuvants pertinents, dans le cadre d'une analgésie multimodale.
Ils peuvent être complétés par des traitements à visée chondroprotectrice et/ou anti-inflammatoire, dont l'efficacité thérapeutique reste à démontrer, mais aussi par des traitements non médicamenteux (acupuncture, physiothérapie).

L'adaptation de l'environnement de l'animal permet aussi d'améliorer son confort au quotidien.
Causes et conséquences d’une rétention vésicale chez le chien et le chat
Authors: Maurey-Guenec Christelle
Published: August 2024

Les causes de rétention vésicale sont multiples chez le chien et le chat. Elles se distinguent selon leur mécanisme : fonctionnelles ou lésionnelles.
Les calculs, les tumeurs sont des des causes communes aux deux espèces.
Les bouchons urétraux sont plus fréquents chez le chat tandis que la dyssynergie vesico sphinctérienne est surtout décrite chez les chiens mâles de grand format.
La présence d’une dysurie, d’une distension vésicale sont des signes qui peuvent orienter vers une rétention vésicale. Cette dernière peut se compliquer d’une insuffisance rénale, d’une atonie du détrusor et est fréquemment associée à une infection du tractus urinaire.
Les incontinences urinaires d’origine neurologique chez le chien et le chat : physiopathogénie, diagnostic et traitement
Authors: Vandenberghe Hélène , Blot Stéphane
Published: August 2024

La continence urinaire résulte d’une coordination entre la phase de stockage des urines par le bas appareil urinaire et la miction. Elle est sous contrôle des nerfs hypogastriques procédant du segment médullaire L1-L4 et pelviens et honteux procédant du segment médullaire S1-S3, dont la coordination est médiée par des réflexes spinaux segmentaires et des voies
supraspinales.
Une incontinence urinaire est fréquemment rencontrée lors de maladie neurologique. On parle de vessie MNC lors d’atteinte suprasacrée, crâniale à S1, à l’origine d’une perte de réflexe de miction.
La cause la plus fréquente est une hernie discale thoracolombaire de stade avancé. Une vessie MNP est consécutive à une atteinte sacrée (S1-S3).
L’obtention d’une anamnèse précise, la réalisation d’un examen clinique et neurologique exhaustif permettent de caractériser précisément
l’incontinence.
Dans certains cas, un profil urodynamique permet d’obtenir des éléments complémentaires et constitue un support pour le suivi. Une prise en charge adaptée et précoce est nécessaire. Toute incontinence urinaire neurogène est responsable d’une rétention urinaire et la vidange vésicale et la surveillance des infections du tractus urinaire constituent les pierres angulaires de la prise en charge, concomitantes au diagnostic et au traitement de la maladie neurologique. L’on pourra s’aider dans certains cas de drogues modulant le fonctionnement de la vessie et des sphincters.
Prise en charge thérapeutique des obstructions urétérales chez le chat
Authors: Manassero Mathieu , Maurey-Guenec Christelle
Published: August 2024

Les obstructions urétérales sont des affections de plus en plus fréquemment diagnostiquées chez le chat. La cause la plus commune est la présence de lithiases oxalocalciques.
Dans ce contexte, le traitement médical correspond principalement à une réanimation pré-opératoire avant un geste chirurgical de reperméabilisation urétérale lorsque le caractère obstructif est clairement démontré.
La dérivation pyélovésicale extra-urétérale semble être un traitement prometteur, malgré le faible recul actuel.
La morbimortalité reste néanmoins élevée avec près de 10 p. cent de mortalité périopératoire, et 10 à 50 p. cent de complications post-opératoires telles que notamment des cystites, des infections ou des obstructions.
Évaluation de la douleur chez les bovins :
les signes de douleur
Authors: Relun Anne , Touzot-Jourde Gwenola , Guénault Rémi , Guatteo Raphaël
Published: August 2024

Les bovins étant des proies, on considère souvent qu’ils expriment peu la douleur, ce qui pourrait retarder sa détection et sa prise en charge. Pourtant, plusieurs signes cliniques, notamment des modifications de comportement et de posture, peuvent être observés chez un bovin douloureux.

Si certains signes paraissent évidents (bruxisme, coups de pattes dans le flanc), d’autres sont plus subtils et nécessitent un examen clinique attentif à distance, puis rapproché pour les déceler. Ces signes doivent être différenciés de signes de stress et de maladie non douloureuse, ce qui nécessite une observation au calme et la prise en compte concomitante de plusieurs signes pour confirmer la douleur.

Plusieurs grilles ont été développées récemment pour détecter et quantifier la douleur chez les bovins. Elles peuvent aider le praticien à mieux évaluer et prendre en charge la douleur chez les bovins au quotidien.
La surveillance de maladies de la faune sauvage
transmissibles au bétail dans le département de l’Orne
Authors: Delafosse Arnaud , Brault Xavier , Achour Hamid
Published: August 2024

L’Orne est un département d’élevage avec de fortes populations de grands ongulés sauvages. Des tensions sont apparues entre les éleveurs et les chasseurs, les premiers soulignant le risque sanitaire pour leurs cheptels et demandant la mise en place d’une surveillance active des maladies transmissibles au bétail sur la faune.

Pour y répondre, le Groupement de Défense Sanitaire et la Fédération des Chasseurs de l’Orne ont déployé, avec l’appui financier du Département, un dispositif complémentaire aux réseaux de surveillance nationaux. Le plan de surveillance a été bâti pour chaque saison de chasse avec les effectifs d’animaux de chaque espèce à prélever. Cet article présente les résultats obtenus entre 2011 et 2016.

La Tuberculose bovine a été recherchée sur plusieurs espèces avec des résultats négatifs. De même, aucune trace de circulation des virus de la Diarrhée virale bovine (BVD) et de la Rhinotrachéite infectieuse bovine (IBR) n’a été relevée sur les cervidés.

À l’opposé, les résultats ont confirmé la réceptivité du cerf aux virus de la Fièvre Catarrhale Ovine (FCO) et de la maladie de Schmallenberg, le chevreuil paraissant plus résistant.

La bactérie de la Paratuberculose n’a été retrouvée que sur un nombre limité de cerfs issus d’un seul massif forestier. Les cervidés dépistés pour la fièvre Q étaient tous négatifs.

Sur les sangliers, les résultats ont montré la présence enzootique de la Brucellose à Brucella suis biovar 2.

Les larves de trichines, les virus de la maladie d’Aujezsky et du Syndrome respiratoire de dysgénésique porcin (SDRP) n’ont pas été détectés. Cette surveillance a permis de clarifier la situation épidémiologique de plusieurs maladies communes aux ongulés sauvages et domestiques et complète utilement les données des réseaux nationaux.
Application of the Relative Citation Ratio to Assess Common Characteristics of the Highest Impact Articles in Reconstructive Microsurgery
Authors: Mahmoud Amir-Ala , Falcon Dominick J. , Bustos Valeria P. , Escobar-Domingo Maria J. , Lee Bernard T.
Published: August 2024

Background The purpose of this review is to characterize themes among the five reconstructive microsurgery articles achieving the highest Relative Citation Ratios (RCRs) published in the past 20 years in the top journals. In doing so, researchers may be better informed on how to propose salient research questions to impact the field and understand future directions in plastic surgery.

Methods A cross-sectional study was conducted with articles published in the top three journals based on the Impact Factor: Plastic and Reconstructive Surgery, Journal of Reconstructive Microsurgery, and Annals of Plastic Surgery. A search strategy with controlled vocabulary and keywords was conducted in PubMed to extract all reconstructive microsurgery (RM) articles published between 2002 and 2020. A two-stage screening process to include only RM studies was performed, with a third reviewer moderating discordances. Articles' RCR data were extracted from the National Institutes of Health iCite. The top five articles with the highest RCRs were selected for analysis.

Results We identified three features reflecting educational and clinical trends within RM that might be representative of super-performance in plastic surgery journals. These include (1) relevance to high-yield techniques in RM such as tissue flap procurement, indications, and outcomes, (2) identification of gaps in current knowledge of these topics, and (3) use of media and algorithms to provide clear recommendations.

Conclusion Researchers hoping to have an impactful contribution should pose research questions that address these key themes. The RCR index is a valuable tool to appreciate performance within microsurgery literature and clinical trends within the field.
The Solid Volume Ratio is Better Than the Consolidation Tumor Ratio in Predicting the Malignant Pathological Features of cT1 Lung Adenocarcinoma
Authors: Liu Yu , Jiang Ning , Zou Zhiqiang , Liu Hongxiu , Zang Chuanhang , Gu Jia , Xin Ning
Published: August 2024

Background More effective methods are urgently needed for predicting the pathological grade and lymph node metastasis of cT1-stage lung adenocarcinoma.

Methods We analyzed the relationships between CT quantitative parameters (including three-dimensional parameters) and pathological grade and lymph node metastasis in cT1-stage lung adenocarcinoma patients of our center between January 2015 and December 2023.

Results A total of 343 patients were included, of which there were 233 males and 110 females, aged 61.8 ± 9.4 (30–82) years. The area under the receiver operating characteristic (ROC) curve for predicting the pathological grade of lung adenocarcinoma using the consolidation–tumor ratio (CTR) and the solid volume ratio (SVR) were 0.761 and 0.777, respectively. The areas under the ROC curves (AUCs) for predicting lymph node metastasis were 0.804 and 0.873, respectively. Multivariate logistic regression analysis suggested that the SVR was an independent predictor of highly malignant lung adenocarcinoma pathology, while the SVR and pathological grade were independent predictors of lymph node metastasis. The sensitivity of predicting the pathological grading of lung adenocarcinoma based on SVR >5% was 97.2%, with a negative predictive value of 96%. The sensitivity of predicting lymph node metastasis based on SVR >47.1% was 97.3%, and the negative predictive value was 99.5%.

Conclusion The SVR has greater diagnostic value than the CTR in the preoperative prediction of pathologic grade and lymph node metastasis in stage cT1-stage lung adenocarcinoma patients, and the SVR may replace the diameter and CTR as better criteria for guiding surgical implementation.
Health Information Technology Documentation and Referrals for Intimate Partner Violence and Sexual Assault
Authors: Richardson Joshua E. , Houston-Kolnik Jaclyn , Ramos Stefany , Oxner Devin , Presler-Jur Paige
Published: August 2024

Background Hospital settings provide a unique opportunity to screen for intimate partner violence (IPV) and sexual assault (SA) yet often lack health information technology (IT) solutions for generating reliable and valid medicolegal documentation via forensic reports.

Objectives The objective of the project was to evaluate a pilot, technology “tool” for documenting cases of IPV and SA that could support forensic nurse examiners and related stakeholders in generating high-quality documentation and coordinating victim support services.

Methods The tool was a digital health intervention implemented for use among forensic nurse examiners, law enforcement, victim support organizations, and more within four counties of California. We conducted a mixed-methods pilot study that captured data around the adoption, use, and impact of having access to the newly implemented tool.

Results The tool successfully went live in all four pilot counties at different time points with different proportions of use by county and form type: exams, referrals, addenda, risk assessments, and other. Participants were motivated to use the tool out of a perceived need for data handling functionalities that went beyond traditional manual (paper) means. Key functionalities included body mapping, data quality controls within validated forms, attaching addenda to already existing case reports, and the means to distribute data to external recipients. Further study and development are needed on functions to incorporate into body maps and forms and understanding the information needs of law enforcement and victim support organizations.

Conclusion Our evaluation demonstrated the feasibility and acceptability of a health IT tool to support forensic nurse documentation of IPV and SA and direct information to multiple legal and support-related stakeholders. Areas of future development include integrating IPV- and SA-related data standards for digitized forms, enhancements to the body mapping feature, and understanding the needs of those who receive digital data from forensic nurse examiners within the tool.
Intravenous Ferric Carboxymaltose-Induced Hypophosphatemia in a Patient with Systemic Lupus Erythematosus: Case Report
Authors: Al Qassimi Sarah , Namas Rajaie , El-Kaissi Samer
Published: August 2024

Anemia is the most frequently observed hematological alteration in patients with systemic lupus erythematosus. Parenteral iron infusion is a highly effective treatment for the commonly encountered condition of iron deficiency. We report a case of an iron-deficient patient who developed severe symptoms due to hypophosphatemia following the administration of intravenous ferric carboxymaltose. These symptoms included feelings of dizziness and muscle cramping. The necessity to inform doctors and patients about this potential consequence has intensified. With this case report, we hope to raise awareness of the start of screening for this complication in the United Arab Emirates. Patients should also notify the doctor for follow-up if their fatigue worsens or if they develop any new musculoskeletal problems.
COVID-19 Vaccination Status among People with Epilepsy Attending a Tertiary Care Epilepsy Clinic: A Cross-Sectional Study
Authors: Shyamsundar Mokmod S. , Nair Pradeep P. , Aghoram Rajeswari , Mohan Sam P. , Sinha Sarthak , Wadwekar Vaibhav
Published: August 2024

Objective The vaccine is the greatest weapon in the battle against the coronavirus disease (COVID) pandemic. Even though COVID-19 vaccines are considered safe in people with epilepsy (PWE), a sizable proportion of PWE are concerned about the safety of vaccines such as precipitation of seizures. The aim of this study was to assess the frequency of COVID-19 vaccine administration, factors affecting the vaccine hesitancy, and side effects of vaccine among PWE.

Methods In this cross-sectional analytical study between December 2021 and August 2022, we included PWE > 15 years attending the epilepsy clinic irrespective of gender. We recorded the demographic and clinical details, COVID-19 vaccination status, and vaccine hesitancy. Those who had received two doses were considered as fully vaccinated.

Results We recruited 226 participants with a median age of 31.5 (15) years. Ninety-six (42.5%) PWE were women and 153 (67.7%) were of rural domicile. Only 96 (42%) had received two or more doses of any COVID-19 vaccine. After vaccination, 45 (30.8%) PWE complained of at least one general side effects and five PWE experienced seizures. Fear of precipitating the seizures was the most common reason for hesitancy in 39 (49%), whereas 26 (33%) PWE were deferred by health care workers. None of the factors such as age (p = 0.366), age of onset of seizures, gender (p = 0.167), domicile (p = 0.090), educational status (p = 0.619), and seizure characteristics (p = 0.675) were associated with vaccination status.

Conclusion Only 96 (42%) PWE were fully vaccinated against COVID-19 and fear of worsening of the seizure frequency was the most common reason for the vaccine hesitancy. Vaccination was associated with seizures in five PWE. A multicentric population-based study may give better information.
Seizure-Related Injuries among Patients with Epilepsy at the Douala General Hospital, Cameroon: A Retrospective Cohort Study
Authors: Nkouonlack Cyrille , Mounchili Adrien Yongho , Gams Daniel Massi , Mbinta James Fenibe , Chichom Alain Mefire , Mapoure Yacouba Njankouo
Published: August 2024

Background Seizures can lead to injuries in patients with epilepsy (PWE). This study seeks to determine the 1-year incidence, types, and associated factors of seizure-related injuries in PWE compared with that of patients without epilepsy.

Methods A retrospective cohort study was carried out at the Douala General Hospital, Douala, Cameroon. Patients with active epilepsy within the past 5 years were compared to patients without epilepsy after matching them by age and gender during a 12-month period. Data was collected from patient records using a questionnaire and analyzed using the SPSS version 20 software. The chi-square test was used to compare the proportions of injuries at a significant level of p < 0.05 and a confidence interval (CI) of 95%.

Results A total of 155 participants were recruited in each group. Note that 51.6% were males, and the mean age was 25.46 ± 16.35 years. The 1-year incidence of all injuries was 26.5% in PWE against 16.8% among patients without epilepsy, respectively (p = 0.038; odds ratio = 1.8, 95% CI: 1.03–3.10). Soft tissue injury was higher in PWE (82.9%, p < 0.05) compared to those without epilepsy (50%), whereas patients without epilepsy had more cases of burns compared to PWE (p < 0.05). PWE and having frequent seizures with falls and those on more than one antiseizure medication had an increased risk of injuries (p < 0.05).

Conclusion PWE have a double risk of having mild soft tissue injuries attributed to epileptic seizures. The risk is increased in PWE having seizures with falls and those taking more than one antiseizure medication.
Y90 Radiation Segmentectomy versus Microwave Ablation for Hepatocellular Carcinoma in Locations Suboptimal for Percutaneous Ablation
Authors: Kola Olivia , Cieslak John A. , Chauhan Nirav , Gupta Priya , Shukla Pratik , Kumar Abhishek
Published: August 2024

Purpose The purpose of our study was to evaluate outcomes following percutaneous microwave ablation (MWA) versus yttrium-90 (Y90) radiation segmentectomy (RS) for tumors in suboptimal locations for ablation.

Materials and Methods Retrospective review (January 2014–July 2019) was performed on patients who underwent Y90-RS or MWA (with or without prior transarterial chemoembolization [TACE]) with curative intent for early-stage hepatocellular carcinoma (HCC) lesions in suboptimal locations for percutaneous ablation, defined as locations in which needle placement is within 5 mm of critical structures (liver dome, liver capsule, gallbladder, and hilum). The primary endpoints were treatment response as per the modified Response Evaluation Criteria in Solid Tumors criteria and complications.

Statistical Analysis Fischer's exact test was performed for categorical variables, and Student's t-tests for nominal variables.

Results Twenty-three lesions in 20 patients (13 male, 67 ± 8.8 years) and 30 lesions in 30 patients (18 male, 62.5 ± 10.6 years) were treated with Y90-RS and MWA (19 with prior TACE), respectively. There were no differences in demographics (p > 0.05). Mean tumor diameter was 2.9 ± 1.0 in those treated with Y90-RS and 2.3 ± 0.9 for MWA (p < 0.05). Lesions were located adjacent to the following structures: dome (n = 22), capsule (n = 16), hilum (n = 9), and gallbladder (n = 6). All patients were Eastern Cooperative Oncology Group performance status 0 to 1. Of the MWA cohort, 19 were Child-Pugh class A, 5 were B, and 6 were C and the mean pretreatment laboratory values were as follows: Model for End-stage Liver Disease sodium (MELD-Na) 12.7 ± 4.6, alpha-fetoprotein (AFP) 848 ± 3168.0, aspartate aminotransferase (AST) 71.9 ± 49.1, alanine aminotransferase (ALT) 48.0 ± 32.4, and total bilirubin 2.4 ± 2.7. Of the Y90-RS cohort, 15 were Child-Pugh class A, 4 were B, and 1 was C and pretreatment laboratory values were as follows: MELD-Na 10.5 ± 3.3 (Y90-RS), AFP 762.2 ± 1793.8 (Y90), AST 50.3 ± 30.5 (Y90), ALT 30.1 ± 16.9 (Y90), and total bilirubin 1.6 ± 1.1 (Y90). Complete response rate following Y90 was 96 versus 76% for MWA, with no disease progression after Y90-RS within the follow-up period. Three (13%) lesions demonstrated progression of disease (time to progression 6.3 months) after MWA. No grade > 2 toxicities or procedure-related complications were noted following Y90-RS. There were 7 major (arterioportal fistula with hemoperitoneum, pneumothorax, liver infarction, and capsular burn) and 3 minor complications following MWA.

Conclusion Y90-RS is a valuable alternative to percutaneous MWA as a first-line therapy for early-stage HCC for tumors in suboptimal locations for ablation, offering a favorable treatment response and safety profile.
Unusual “Mini-Rugby Ball” Pattern Solitary Lung Metastasis in Relapsed Ewing's Sarcoma
Authors: Gondhane Abhay , Sonavane Sunita N. , Basu Sandip
Published: August 2024

Ewing's sarcoma (ES) is a mesenchymal origin malignant neoplasm that affects children and adolescents. It is the second most common type of bone sarcoma and accounts for approximately 1.5% of all childhood cancers with an annual incidence of 1 to 3 cases per million children under 16 years of age. In this article, we present the case of a 16-year-old adolescent girl. Lung metastasis at the initial diagnosis of ES is relatively uncommon but carries significant prognostic implications. Lung metastases in ES can vary significantly in size, ranging from small nodules (just a few millimeters in size) to the largest reported case being 15 cm. The size of the metastases impacts the choice of therapeutic strategies and the prognosis. Approximately 30% of patients with ES experience a relapse, with the lungs being a common site for metastatic disease. Relapsed lung metastasis on follow-up is a critical concern in the long-term management of ES. We describe a relapsed case of ES in a 16-year-old adolescent girl who presented with a solitary large metastatic right lung mass, with the longest dimension of 16 cm on craniocaudal measurement. The primary site of the tumor was the left distal femur, for which the patient received six cycles of neoadjuvant chemotherapy, followed by en bloc tumor excision and rotationplasty of the left distal femur, after which the patient received seven cycles of adjuvant chemotherapy. Subsequent 5 years of regular follow-up was asymptomatic. Later, the patient presented with back pain and cough, and was diagnosed with a solitary large right lung mass. Computed tomography (CT) guided biopsy of the right lung mass revealed a metastatic ES, for which she underwent chemoradiotherapy. This case highlights the large size of solitary lung metastases in relapsed ES.
Development of a Porcine VCA Model Using an External Iliac Vessel-Based Vertical Rectus Abdominus Myocutaneous Flap
Authors: Blades Caitlin M. , Greyson Mark A. , Navarro-Alvarez Nalu , Mathes David W. , Dumanian Zari P. , Yu Jason W. , Wang Yong , Li Bing , Wang Zhaohui , Washington Kia M. , Huang Christene A.
Published: August 2024

Background Vascularized composite allotransplantation (VCA) involves transplanting a functional and anatomically complete tissue graft, such as a hand or face, from a deceased donor to a recipient. Although clinical VCA has resulted in successful outcomes, high rates of acute rejection and increased requirements for immunosuppression have led to significant long-term complications. Of note, immunosuppressed graft recipients are predisposed to infections, organ dysfunction, and malignancies. The long-term success of VCA grafts requires the discovery and implementation of unique approaches that avoid these complications altogether. Here, we describe our surgical technique and initial experience with a reproducible heterotopic porcine VCA model for the preclinical assessment of approaches to improve graft outcomes.

Methods Six heterotopic porcine allogeneic vertical rectus abdominis myocutaneous flap transplants were performed using Sinclair donors and Yucatan recipients. Immunosuppressive therapy was not used. Each flap was based on the left external iliac vessel system. Animals were followed postoperatively for surgery-related complications.

Results The six pigs underwent successful VCA and were euthanized at the end of the study. Each flap demonstrated complete survival following vessel anastomosis. For the allogeneic recipients, on average, minimal erythema and healthy flap color were observed from postoperative days 1 to 4. There were no surgery-related animal deaths or complications.

Conclusion We have developed a reproducible, technically feasible heterotopic porcine VCA model based on the left external iliac vessel system. Our results demonstrate this model's potential to improve VCA graft outcomes by exploring tolerance induction and rejection biomarker discovery in preclinical studies.