bluuebunny/crossref_metadata_2025 huggingface dataset:
GESTÃO PATRIMONIAL: perspectivas do controle contábil e extra contábil de acervos bibliográficos físicos em bibliotecas de instituições públicas federais
Authors: Barreto Isaias Cristino Esteves , Rebouças Porto Júnior Francisco Gilson , Eduardo Moura Costa Wendell
Published: October 2022

As particularidades inerentes aos diversos tipos de bibliotecas as configuram como um ambiente propício à implementação de inovações em seus processos administrativos. Como um desses processos destaca-se a gestão patrimonial dos acervos bibliográficos físicos, que se consolida como fulcral na estrutura organizacional das bibliotecas, nessa pesquisa especificaremos as bibliotecas das universidades públicas federais que corroboram com essa perspectiva. A presente pesquisa tem o objetivo de apresentar fatores que podem interferir na qualidade da gestão patrimonial dos acervos bibliográficos físicos com o propósito de oportunizar uma reflexão sobre a possibilidade de implementar inovações junto ao processo. A pesquisa foi delineada metodologicamente através da pesquisa bibliográfica, que permitiu aos pesquisadores terem um embasamento teórico construtivo sobre o que já foi estudado na temática. Como resultado, tornou-se perceptível a complexidade do processo de segurança do acervo bibliográfico físico frente à vulnerabilidade dos materiais informacionais e a quantidade de variáveis que agem sobre eles, intensificando esse cenário de degradação.
PERAN ORANG DEWASA TERHADAP PROSES PERKEMBANGAN BAHASA ANAK
Authors: Widyaswarani Elyvia
Published: October 2022

ABSTRAK:

Bahasa memiliki peran penting dalam kehidupan manusia. Selain sebagai medium untuk melakukan tindakan, bahasa juga berfungsi sebagai cerminan budaya penuturnya. Bahasa adalah sumber kehidupan dan kekuatan.Bahasa dapat mengontrol perilaku, merealisasikan tindakan dan mengubah situasi. Pemerolehan bahasa pada anak usia 1-3 tahun merupakan proses yang bersifat fisik dan psikis. Secara fisik, kemampuan anak dalam memproduksi kata-kata ditandai oleh perkembangan bibir, lidah, dan gigi mereka yang sedang tumbuh. Pada tahap tertentu pemerolehan bahasa (kemampuan mengucapkan dan memahami arti kata juga tidak lepas dari kemampuan mendengarkan, melihat, dan mengartikan simbol-simbol bunyi dengan kematangan otaknya). Sedangkan secara psikis, kemampuan memproduksi kata-kata dan variasi ucapan sangat ditentukan oleh situasi emosional anak saat berlatih mengucapkan kata-kata. Anak-anak yang mendapatkan bimbingan dan dorongan moral yang sangat kuat akan memperoleh kata-kata yang banyak dan bervariasi dibandingkan anak-anak lainnya.

Kata kunci : bahasa, pemerolehan, kata
Rancang Bangun Alat Pendeteksi Kualitas Telur Berbasis Arduino Dengan Sistem Fuzzy Logic
Authors: Anggraini Dewi Fitri , Sudarmaji Arief , Listanti Riana
Published: October 2022

Memeriksa kualitas telur menggunakan metode konvensional dan dengan inderawi manusia tidak selalu menghasilkan pemeriksaan yang tepat. Namun, pemeriksaan dengan memecahkan cangkang telur, bersifat destruktif dan tidak dapat digunakan oleh penjual telur. Karenanya dibutuhkan alat yang dapat mendeteksi kualitas telur dengan tepat dan bersifat non-destrukif. Beberapa peneliti telah menciptakan alat pendeteksi kebusukan telur dengan menggunakan mikrokontroler. Namun, alat pendeteksi kualitas telur ini masih memerlukan pengembangan. Penelitian ini bertujuan untuk merancang bangun alat pendeteksi kualitas telur berbasis Arduino menggunakan pengukuran intensitas cahaya, bau, dan bobot dan mengetahui kinerja masing-masing unit pengukuran dan alat secara keseluruhan. Metode analisis data yang digunakan pada penelitian ini yaitu pengujian komponen alat dengan metode blackbox, termasuk menguji tiga sensor pengindra yang digunakan alat yaitu sensor MQ-2, sensor LDR, dan load cell. Pengujian keseluruhan kerja alat, pengukuran Indeks Putih Telur (IPT) dan Indeks Kuning Telur (IKT. Berdasarkan hasil penelitian, alat pendeteksi kualitas telur mampu membedakan telur berkualitas baik dan buruk. Semua komponen alat menghasilkan output yang diharapkan kecuali sensor MQ-2. Sensor MQ-2 tidak berhasil menangkap konsentrasi gas H2S yang keluar dari dalam sampeltelur busuk, namun dengan dua sensor pengukuran lainnya yaitu sensor LDR dan load cell, alat memiliki akurasi pemeriksaan sebesar 97.77%.
bahasa indonesia
Authors: YUWONO TRIAT ADI
Published: October 2022

Sonic bloom is an eco-friendly technology that uses sound waves to stimulate stomata to open which then increases the rate and efficiency of nutrient absorption in the leaves. This research examined the Effect of Soonic Bloom Using Asmaul Husna on the Growth of Mustard Green plants in Karangsalam Kidul Village, Kedungbanteng Sub-district, Banyumas District. This research was intended to: (1) determine the effect of Asmaul Husna reading on the growth of mustard green plants; (2) identify the significance of the Asmaul Husna reading on the growth of mustard green seeds. A completely randomized design (CRD) with three treatments was employed, namely (A) using classical music, (B) silent control treatment, and (C) using Asmaul Husna recording. The sound intensity ranged from 64.3-73.3 dB. The results of this research showed that: (1) exposure to Asmaul Husna reading had the highest effect on the germination process, leaf length and mustard green leaves width of other treatments, (2) the ANOVA test outcome indicated a significant difference in the width of mustard green leaves exposed to classical music compared to the ones exposed to silent treatment and Asmaul Husna reading.
Authors: Ropiudin Ropiudin - , Yanti Andina Lies , Ritonga Abdul Mukhlis , Margiwiyatno Agus
Published: October 2022

Tofu is a food that contains protein and is made from soybean juice obtained through the fermentation process of soybeans. An increase in tofu consumption results in an increase in energy demand in a tofu processing industry. Energy use that is carried out efficiently can be done by means of an energy audit that will get the energy used and know how to save it. This study aims to 1) determine the energy requirements of each tofu processing process, 2) determine the form, source and amount of energy used in the tofu processing production process in Sampang Village and Brani Village, Sampang District, Cilacap Regency, Central Java, 3) find out the comparison of the efficiency levels of the two tofu processing industries in Sampang Village and Brani Village, Cilacap District, Central Java, and 4) identify the results of the comparison of data obtained from the two tofu processing industries to make an effort to save energy or diversify energy use. This research was conducted on two small industries in Sampang Village owned by Mr. Maryo and Mr. Sholeh's Brani Village located in Sampang District, Cilacap Regency, Central Java. This research was carried out from February 2021 to April 2021. The sampling was carried out on these two industries in order to obtain energy data and observe the differences in the tools used when processing the tofu. The data collection method is carried out for each production in one day. Variables obtained from data collection include the amount of tofu production per day, energy requirements for biomass fuels (rice husks and firewood), human energy needs, electrical energy requirements, diesel fuel energy requirements, and energy requirements for ballast stones.  The results showed that the energy needed in the tofu processing industry Mr. Maryo was 779.06 MJ or 5.19 MJ/kg obtained from energy sources such as human energy (33.47 MJ or 0.22 MJ/kg), biomass fuel energy (552, 29 MJ or 3.68 MJ/kg), and diesel fuel energy (193.30 MJ or 1.29 MJ/kg).The energy used in the tofu processing industry belonging to Mr. Maryo is 244.81 MJ or 1.63 MJ/kg which comes from the energy used in this industry such as human energy (18.43 MJ or 0.12 MJ/kg), biomass fuel energy (122.54 MJ or 0.82 MJ/kg), and diesel fuel energy (103.84 MJ or 0.69 MJ/kg). The results of research on the tofu processing industry of Mr. Sholeh amounted to (2205.77 MJ or 6.302 MJ/kg) obtained from energy sources such as human energy of (33.47 MJ or 0.10 MJ/kg), biomass fuel energy (2109.60 MJ or 6,03 MJ/kg), and electrical energy (62.70 MJ or 0.18 MJ/kg). The energy used in Sholeh's tofu processing industry (298.74 MJ or 0.86 MJ/kg) comes from energy used in industries such as human energy (32.22 MJ or 0.09 MJ/kg), biomass fuel energy (214.11 MJ or 0.61 MJ/kg), and electrical energy (52.41 MJ or 0.15 MJ/kg).
Optimization of Phenol Levels from Phycoerythrin of Gracilaria verrucosa with Freeze Thaw using Response Surface Methodology
Authors: Maksum Ali , Purbowati Ike Sitoresmi Mulyo , Wijonarko Gunawan , Anggriawan Rian
Published: October 2022

Gracilaria verrucosa is a one of the seaweeds with a red pigment in the form of phycoerythrin. Phycoerythrin pigment contains phenol which is an antioxidant. The pigment can be obtained by extraction. One of the extraction methods that can be done is freeze thaw. This study uses the Response Surface Methodology to obtain the optimum sample. The purpose of this study was to determine the optimization model, the optimum point and the phenol content of the phycoerythrin Gracilaria verrucosa using the freeze thaw using Response Surface Methodology. Extraction of phycoerythrin pigment was carried out using the freeze thaw with a factor of freeze time, thawing time and solvent ratio, then the phenol content test was carried out. The results obtained are that the mathematical model used for optimization is the quadratic method with the equation y = 148.71 – 3.47(A) + 20.94(B) + 32.36(C) + 10.94(AB) + 9 .90(AC) + 6.25 (BC) + 6.52(A2) – 15.57(B2) + 30.46(C2). The optimum response obtained is the freeze duration 121,964 minutes; thawing duration 144,281 minutes; and the solvent ratio is 62.556%, and the phenol content obtained is 163.742 g GAE/g.
Information Theory of Gravity
Authors: Abanto Jeffrey Alloy
Published: October 2022

A new model of gravity is presented here similar to the earlier work of Verlinde on Emergent Gravity but without the use of thermodynamic assumptions. The theory does not use the main assumption of Verlinde on the nature of gravity as an entropic force using the First Law of Thermodynamics. Moreover, it does not use the Equipartition Theorem such that there is no need to define a thermal bath enclosed within a holographic screen. Instead of Equipartition Theorem, the theory uses $E=NE_{p}$, for the total energy of a massive object where $E_{p}$ is the Planck Energy while $N$ is the number of Planck Energy to represent the maximum possible density of information that can reside in matter. The theory uses also the Holographic Principle as the basis for an information-theoretic approach to the nature of gravity. It is shown here that gravity emerges whenever there is an updating of the information within a given volume of space by the presence of matter.
On Virtual Scalar Fields in a Conformally Flat FLRW Spacetime
Authors: Casado Eide Adrian
Published: October 2022

The case of a virtual bosonic scalar field phi(x) gravitationally coupled in a conformally flat spacetime is investigated. The action S is known to be Weyl invariant only for specific expressions of the potential V(phi). In the conformally flat FLRW case the harmonic angular frequency omega_k(eta) becomes uniquely temporally independent. Therefore any inertial observers embedded in a conformally flat FLRW spacetime all agree on the choice of virtual vacuum states. We postulate that the wavenumber k must be quantized in order to be able to regulate the vev by zeta regularization. Some fundamental implications of this result is derived, and likely conclusions drawn.
Home-range Size and Space Use of Territorial Bonelli’s Eagles (Aquila Fasciata) Tracked by High Resolution GPS/GSM Telemetry.
Authors: Morollón Sara , Urios Vicente , López-López Pascual
Published: October 2022

The current advent of GPS/GSM technology, with high resolution GPS dataloggers available, provides information of the highest quality, which is certainly better than previous tracking methods such as ARGOS telemetry or conventional VHF ground-tracking. As a result, this has improved our knowledge of home-range behavior and spatial ecology of many species, including large raptors. In this paper, we use satellite telemetry information to assess the home-range size and the role of individual, year, sex and season (breeding or non-breeding season) in space use of the Bonelli’s eagle (Aquila fasciata). To this end, 51 territorial individuals (25 females and 26 males) were equipped with GPS/GSM transmitters and were tracked over a 7-year period (2015-2021) in eastern Spain. Overall, we recorded 4,791,080 fixes that were analyzed through kernel density methods (50%, 75% and 95% fixed kernels). Average home-range size according to the 95% kernel, 75% kernel and 50% kernel were 54.84 ± 20.78 km2, 24.30 ± 10.18 km2 and 11.17 ± 4.90 km2, respectively. The home-range size of individuals occupying the same territory was similar, mainly due to the cooperative hunting behavior exhibited by the species. No interannual differences in the home-range of the same territory were found, showing a strong territorial fidelity of the breeding pairs. Overall, females’ home-range size were smaller than males’ ones due to the decrease of activity in the breeding season due to laying, incubation and chicks attendance at nests. No seasonal variation in the general home-range size was found. Moreover, we found low neighbor overlap among territories (4,18% ± 3.06%) that evidences a high level of intraspecific competition in Bonelli's eagles. Finally, this study highlights the advantages of the use of accurate telemetry information to improve our understanding of the spatial ecology of the endangered Bonelli’s eagle, which ultimately will serve to better inform management actions for its conservation.
Electrochemical Immunosensor Based on Carboxylated Graphene/SPCE for Igg-SARS-Cov-2 Nucleocapsid Determination
Authors: Brito Walter , Freire Luciana , Ruzo Camila , Salgado Bárbara , Gandarilla Ariamna María Dip , Romaguera-Barcelay Yonny , Tavares Ana , Sales Maria Goreti Ferreira , Cordeiro Isabelle , Lalwani Jaila , Matos Robert S. , Fonseca Filho Henrique Duarte da , Astolfi-Filho Spartaco , Lalwani Pritesh , Ţălu Ştefan
Published: October 2022

The COVID-19 pandemic has highlighted the importance and urgent need of rapid and accurate diagnostic tests for detection and screening of this infection. In our proposal, a biosensor based on the ELISA immunoassay was developed for monitoring antibodies against SARS-CoV-2 in human serum samples. The SARS-CoV-2 nucleocapsid protein (N-protein) was selected as a specific receptor for the detection of SARS-CoV-2 nucleocapsid immunoglobulin G. Thus, the N-protein was immobilized on surface of screen-printed carbon electrode (SPCE) modified with carboxylated graphene (CG). The IgG-SARS-CoV-2 nucleocapsid concentration was quantified using a secondary antibody labelled with horseradish peroxidase (HRP) (anti-IgG-HRP) catalyzed by 3,3’,5,5’-tetramethylbenzidine (TMB) mediator by chronoamperometry. A linear response was obtained in the range of 1:1000-1:200 v/v in phosphate buffer solution (PBS) and the limit of detection calculated was of 1:4947 v/v. The chronoamperometric method showed electrical signals directly proportional to antibody concentrations due to Ag-Ab specific and stable binding reaction.
Syzygium cumini Seeds: A Potential Source of Human Nutrition and Health
Authors: Dangi Sushma , Singh Dr. Vishakha
Published: October 2022

Syzygium cumini, generally renowned as jamun, is a tropical tree that yields purple ovoid fleshy fruit. Jamun is having a very good market value, but due to its unavailability and perishability it is still unexploited. Its seed has been conventionally used in India for the management of different ailments. The present investigation was carried out to understand the chemical composition of jamun seed by analyzing various parameters such as moisture, crude protein, crude fat, ash, crude fibre, carbohydrate and energy per 100 g on dry weight basis. The findings revealed that jamun seed consisted of moisture (6.67±4.76 g), crude protein (5.54±0.26 g), crude fat (1.43±0.02 g), ash (2.34±0.10 g), crude fiber (6.02±0.06 g), carbohydrate (77.99±3.34 g) and energy (347.01±18.19 kcal per 100 g. Proximate composition of jamun seed indicated that it is low in fat content and encompasses with good protein and fibre content. The results showed that jamun seed have adequate dietary nutrients and can be recommended in various lifestyle disorders.
Evaluation of Antioxidant Potentialities of Whole Fruit Juices from Ximenia americana Linn., Vitex doniana Sweet. and Annona senegalensis Pers
Authors: Moffo Foning Ludovic , Fombang Édith , Clergé Tchiegang
Published: October 2022

Ximenia americana Linn. (Olacaceae)., Vitex doniana Sweet. (Verbenaceae) and Annona senegalensis Pers. (Annonaceae) are three endemic fruit species growing in dry African savannahs. The fruits produced by these species have unique and highly appreciated organoleptic characteristics (aromas and flavors). However, their consumption is limited to the localities where they are found. In addition, the rarity of scientific information on their technological and nutritional potentials constitute an obstacle to their valorization. To bridge this gap, a comparative evaluation of the antioxidant potential of the whole fruit juices from these species was carried out. After physicochemical characterization of the fruits, anti-radical power and reducing activity of the juices were determined using DPPH, ABTS, FRAP and TAC methods. The physicochemical analyses of A. senegalensis indicated values of 7.65 ± 0.99 % (proteins), 32.81 ± 1.08 % (total sugars), 3.98 ± 0.17 % (ash) in opposite to 5.68 ± 0.17 (proteins), 42.45 ± 1.54 % (total sugars), 2.03 ± 0.2 % (ash) of X. americana and 2.97 ± 0.74 % (proteins), 33.62 ± 1.79 % (total sugars), 1.36 ± 0.19 % (ash) of V. doniana. The A. senegalensis juice had the highest total phenolic and flavonoid contents respectively 1.22 ± 0.01 and 0.36 ± 0.03 g/100 g of FW compared to X. americana (731.93 ± 2.25 and 295.58 ± 1.67 g/100 g respectively) and V. doniana (633.18 ± 1.93 and 111.09 ± 2.44 respectively). A. senegalensis and X. americana had the highest anti-radical activities by DPPH (12.50 ± 0.01) compared to V. donianaand vitamin C standard (8.33 ± 0.02). The ABTS test for the juices from V. doniana and A. senegalensis (14.28 ± 0.01) was compared to X. Americana (9.90 ± 0.01) and vitamin C standard (6.66 ± 0.02). Juices from X. americana had the highest TAC reducing capacity (570.67 ± 1.14 mg EAA / 100 g of FW) compared to V. doniana (521.15 ± 1.93) and A. senegalensis (147.78 ± 2.75). The FRAP test indicated values of 1401.04 ± 1.82 mg/100 g of FW in opposite to X. americana (798.79 ± 1.51) and V. doniana (600.19 ± 2.37). Flavonoids are strongly correlated to antioxidant activity by FRAP (r=0.86) and DPPH (r = 0.96). Tannins (r = 0.98) are strongly correlated with the TAC test.
Food Consumption and Nutritional Status of Urban Low Middle-income Families
Authors: Kumari Honey , K Kalaivani , Ramachandran Prema
Published: October 2022

In the 1970s Green Revolution enabled India to become self-sufficient in food production, but poverty, low dietary intake and under-nutrition were high. India identified poor families on the basis of energy consumption, provided employment to these families to improve purchasing power, subsidized food grains through PDS to improve family food security and food supplementation through ICDS to children and women from poor families to bridge the gap in their dietary intake. Over years, there has been a decline in under-nutrition but rate of decline was slow. The country is currently having persistent high under-nutrition in children, rise in over-nutrition in adults and increasing intra-family differences in nutritional status. A study was taken up in 547 urban low middle-income families with dual nutrition burden, to assess the current food and macronutrient consumption and food security status of the families and the nutritional status of the individual family members. The average energy intake of these families was 1900 Kcal. This was lower than the EAR for reference population (2110 Kcal/day) but higher by 140 Kcal when compared to the EAR for average Indian population (1760 Kcal/day). In pre-school and school-age children stunting rates were high but wasting and over-nutrition rates were low. Over-nutrition rates in adults were high perhaps due to higher energy intake as compared to the requirements for the short-statured sedentary adults. In view of these findings, it may be useful to explore a dual approach: programmes aimed at improving household food security continue to focus on families; while programmes aimed at improving nutritional status focus on anthropometric screening of individual members (children and adults) for early identification of under-or over-nutrition, appropriate management and monitoring improvement.
Gender, Race/Ethnicity, and Unionization in Direct Care Occupations
Authors: Dill Janette , Tanem Jill
Published: October 2022

Objectives. The goal of this study was to measure unionization in the direct care workforce and the relationship between unionization and earnings, looking closely at differences across race/ethnicity and gender.

Methods. Using data from the Current Population Survey from 2010 to 2020, we first used logit analyses to predict the probability of unionization among direct care workers across race/ethnicity and gender. We then measured the relationship between unionization and weekly earnings.

Results. We found that male (12%) and Black (14%) direct care workers were most likely to be unionized, followed by Hispanic and other direct care workers of color. Unionized direct care workers earn wages that are about 7.8% higher than nonunionized workers, but unionized workers of color earn lower rewards for unionization compared with White direct care workers.

Conclusions. Unions are a mechanism for improving job quality in direct care work, and protecting workers’ rights to unionize and participate in collective bargaining equitably may be a way to stabilize and grow the direct care workforce. (Am J Public Health. 2022;112(11):1676–1684. https://doi.org/10.2105/AJPH.2022.307022 )
Original research article digital literacy in EFL learning: University students’ perspectives
Authors: Pertiwi Intan
Published: October 2022

The 21st century has widely opened the opportunity for society, specifically in the educational party, to excel their performance in digital literacy. This relates to the competence required in accessing information using media and ICT tools in the process of learning. Technology integration in EFL learning has been a common issue, yet studies in digital literacy in language learning are still scarcely being conducted. This study explores university students’ digital literacy skills and their perspectives on digital literacy in EFL learning. Two instruments were utilized through a qualitative method, including a questionnaire and interview. The findings showed some aspects of digital literacy influencing students’ EFL learning. This involves students’ information literacy, ICT and media literacy, and their perspectives on digital literacy. The result indicated that EFL university students are encouraged to apply digital literacy since almost all learning components are integrated with digital technologies. As a consequence, they showed high awareness to keep up with the latest issue on digital literacy in their EFL learning.
Bivariate, high-content screening of Brugia malayi microfilariae
Authors: Wheeler Nicolas J. , Ryan Kaetlyn T. , Gallo Kendra J. , Zamanian Mostafa
Published: October 2022

The following protocol is for performing bivariate (motility and viability) phenotypic drug screens against Brugia spp. microfilariae (mf). It has been heavily optimized for utilization with an ImageXpress high-content imager, but only small adaptations will be necessary for usage with similar imaging platforms.Mf are used immediately after receipt/extraction, and the experiment should not be run longer than 48 hours, after which mf health rapidly deteriorates. We have had success recording motility at 12 hours post-treatment (hpt) and again at 36 hpt, after which mf are immediately stained for viability, as well as 24/48 hpt time points.The two phenotypes could be assayed separately, but we have found that not every compound that causes reduction in mf motility causes a concomitant loss of viability. Thus, the discriminatory power of the pipeline is increased by running both assays in parallel, using the same plates. We have run the experiment using 16 plates at a time which will necessitate several hours of imaging at the desired time points. If several plates are planned, drug addition will need to be staggered every 5-6 minutes in accordance with the time taken to completely image each plate.Image data can be analyzed via a variety of software, but we have designed wrmXpress for this purpose (1).
Aspects of separate psychiatric care for adolescents: A review of adolescent inpatient care and propositions for future efforts
Authors: Kalkofen Maja , Vehoff Charlotte , Müller Helge
Published: October 2022

Background: Adolescence, the transitional phase between child- and adulthood, represents a sensitive period. Vulnerability to mental illness is thus increased at a young age. Chronicity and impairments must be prevented through targeted interventions. In addition, the developmental processes taking place at this age, e.g. identity development, ought to be taken into account simultaneously. Adolescents seem to be too old for child and adolescent psychiatry and too young for adult psychiatry. The need for a distinct treatment program for this age group is already discussed in the literature. However, so far it presents to be difficult to summarize which characteristics such an offer must contain.
Methods: In the present review, we selected and evaluated relevant literature regarding our research questions. We performed a thorough web- and data-based search (databases PubMed, PsycInfo and Google Scholar) of peer-reviewed journals on a variety of relevant key terms. Based on the studies, we provide an overview of the various aspects that appear to be of importance. In addition, keywords were developed in order to subsequently establish guiding categories for practical implementation.
Results: 30 peer-reviewed articles were identified that matched the agreed-on screening criteria. The following important categories could be formed: Therapeutic characteristics of an adolescent ward, Structural framework on the ward, Psychosocial support, Family involvement, Inclusion of outpatient facilities, Multidisciplinary team, Professional training opportunities, Structure in care system, Further research and Environmental context. We ordered the categories according to their relevance. Discussion: By forming the categories, it was possible to create an overview of the most frequently mentioned relevant aspects for transitional psychiatry in the literature. Despite the fact, that adolescence psychiatry is increasingly coming into focus, research is scarce. Specifically, there is a lack of explicit practice approaches and models. Therefore, we suggest that further studies should be conducted to review and produce reliable manuals that support the elements we have distinguished in this review. The established categories can be further used as a basis for an implementation into practice. However, empirical verification is pending, which is a limitation of this work.
Conclusions: A deeper understanding of relevant treatment characteristics for the transitional age group may not only enable a tailored treatment approach but may also facilitate the implementation of separate psychiatric wards for adolescents. This literature review identified several aspects that appear to be of importance in the psychiatric treatment of adolescent patients. Considering the alarming increase in psychiatric disorders worldwide, new treatment programs targeted at the transitional age group should be developed to reduce the manifestation and preservation of mental disorders.
WITHDRAWN: Research on the compression of similariton laser beam based on Dispersion-decreasing Fiber
Authors: zhang qiaofen , Pang Liangyu , Wu Liming , Wang Guitang , Gao Jian , Deng Yaohua , Gao Zihao , Chen Chubang
Published: October 2022

The interaction and compression of the similariton beam generated in a mode-locked similariton laser system and compressed in a DDF (dispersion-decreasing fiber) with negative dispersion is investigated in this paper. First, a quality factor R is established to evaluate the quality of compressed similariton beams to design optimum tapered DDF. The result shows that the hyperbolically tapered DDF can achieve a best R compared to the linearly tapered DDF, exponentially tapered DDF, Gaussian tapered DDF, cosinoidally tapered DDF and logarithmically tapered DDF. Then, a pedestal energy ratio PE and a compression quality parameter Q are further established to evaluate the quality of compressed output beams considering the pulses with and without interaction by adjusting the time-delay q0 between the pulse pairs in a hyperbolically tapered DDF. Finally, we obtain the optimum compressed pulse pair both considering q0 = 4ps and q0 = 2.6ps, the pedestal energy ratios are 3.0048% and 13.4306%, maximum compression quality parameters are 454.3059 and 293.1326, the corresponding FWHM and peak power are 177.3fs and 302.2695W, 189.7fs and 249.4017W, respectively, demonstrating efficient and high-quality similariton beam compression.
Simplified regimen of combined low-dose rituximab for autoimmune encephalitis with neuronal surface antibodies
Authors: Du Ying , Zhao Chao , Liu Juntong , Li Chuan , Yan Qi , Li Lin , Hao Yunfeng , Yao Dan , Si Huaxing , Zhao Yingjun , Zhang Wei
Published: October 2022

Background:Autoimmune encephalitis (AE) with neuronal surface antibodies (NSAbs) presents pathogenesis mediated by B-cell-secreting antibodies. Rituximab is a second-line choice for the treatment for AE with NSAbs, which can cause B cell depletion via targeting CD20. However, the optimal protocol and dosage of rituximab combined with first-line therapy for NSAbs-associated AE remains unclear so far. In this study, we explored the efficacy and safety of low-dose rituximab combined with first-line treatment for NSAbs-associated AE.
Methods: Fifty-nine AE patients with NSAbs were enrolled, and retrospectively divided into common first-line therapy (41 patients) and combined low-dose rituximab (100mg induction weekly with 3 circles, followed by 100mg reinfusion every 6 months) with first-line therapy (18 patients). Outcome measures included changes in the Clinical Assessment Scale for Autoimmune Encephalitis (CASE) score (primary endpoint), changes in the modified Rankin Scale (mRS), the Mini-mental State Examination (MMSE), the patient and caregiver Neuropsychiatric Inventory (NPI) score at each visit (baseline, discharge, 6 months, 12 months and last follow-up) between two groups (secondary endpoint), as well as oral prednisone dosage, relapse and adverse effects during follow-up.
Results: Compared with traditional first-line therapy group, for primary outcome, CASE scores at last follow-up were significantly improved in combined rituximab group, as well as markedly improving changes of CASE scores between baseline and each visit. While changes of mRS, MMSE and NPI scores, as secondary endpoint, were all markedly accelerating improvement between baseline and each visit, as well as both oral prednisone dosage and relapse were also greatly reduced during follow-up. Meanwhile, longitudinal analysis in combination of rituximab cohort also revealed persistently marked amelioration in a series of scales from baseline even more than 1 year. Moreover, analysis in rituximab subgroup showed no difference in any clinical outcomes between combination with single first-line and with repeated first-line treatment (≥2 times), while compared to delayed combination with rituximab (>3 months), early initiation of combination (≤3 months) might achieve better improvements in CASE and MMSE assessment even 1 year later. No rituximab correlated serious adverse events have been reported in our patients.
Conclusions: Our simplified regimen of combined low-dose rituximab firstly showed significantly accelerating short-term recovery and long-term improvement for AE with NSAbs, in parallel with markedly reduced prednisone dosage and clinical relapses. Moreover, opportunity of protocol showed earlier initiation (≤3 months) with better long-term improvement.
Massively parallel electro-optic sampling of space-encoded optical pulses for ultrafast multi-dimensional imaging
Authors: Kim Jungwon , Na Yongjin , Kwak Hyunsoo , Ahn Changmin , Lee Seung Eon , Lee Woojin , Kang Chu-Shik , Lee Jungchul , Suh Junho , Yoo Hongki
Published: October 2022

High-speed and high-resolution imaging of surface profiles is critical for the investigation of various structures and mechanical dynamics of micro- and nano-scale devices. In particular, recent emergence of various nonlinear, transient and complex mechanical dynamics, such as anharmonic vibrations in mechanical resonators, has necessitated real-time surface deformation imaging with higher axial and lateral resolutions, speed, and dynamic range. However, real-time capturing of fast and complex mechanical dynamics has been challenging, and direct time-domain imaging of displacements and mechanical motions has been a missing element in studying full-field structural and dynamic behaviours. Here, by exploiting the electro-optic sampling with a frequency comb, we demonstrate a line-scan time-of-flight (TOF) camera that can simultaneously measure the TOF changes of more than 1000 spatial coordinates with hundreds megapixels/s pixel-rate and sub-nanometre axial resolution over several millimetres field-of-view. This unique combination of performances enables fast and precise imaging of both complex structures and dynamics in three-dimensional devices and mechanical resonators.
Workplace-based assessment in the Bhutanese context: acceptability, feasibility, and educational impact as perceived by trainees and trainers
Authors: Tenzin Karma , Giri Sweta , Tshering Ugyen , Choeda Tshering , Gyamtsho Sonam , Misganaw Equlinet , Siebeck Matthias
Published: October 2022

Background:The Postgraduate Medical Education globally has transited from traditional cognitive based to more competency-based learning. Bhutan’s only medical university, Khesar Gyalpo University of Medical Sciences of Bhutan (KGUMSB) introduced Competency Based curriculum (CBC) through implementation of workplace-based assessment (WPBA) in June 2018. The proposed competency-based curriculum (CBC) was aimed at developing appropriate competencies in the learners through workplace-based assessment. A programmatic evaluation of the trainees and trainer’s perception on implementation of workplace-based assessment for three years at KGUMSB was conducted in July-Sept 2021.
Methods: The evaluation was conducted in July-Sept, 2021. The mixed methods design was utilized such as survey, review of student portfolios and focus group discussion. A total of 62 participants (46 residents in clinical training and 16 faculty members) participated in this evaluation.
Results: After three years of implementation of WPBA, it was perceived as a good system of assessing learners with a high level of acceptability among both the students and faculty members. The practice of providing immediate feedback was well appreciated by students.
Conclusions: These findings support that WPBA is a good assessment system in postgraduate education. However, it was also evident that issues such as perceived time constraints, overburdened students and lack of faculty capacity were possible obstacles to proper implementation of WPBA.
Analysis of water film distribution and aerodynamic characteristics of high-speed train under rainfall environment
Authors: Li Meixiang , Yu Mengge , Liu Jiali , Sheng Xugao
Published: October 2022

In the rainfall environment, the water film is formed on the body surface of the high-speed train when raindrops impact the train. The water film interacts with the flow field around the train, thereby affects the aerodynamic characteristics of the high-speed train. In this paper, based on SST k-w turbulence model and Euler-Lagrange discrete phase model, the aerodynamic calculation model of high-speed train under rainfall environment is established, and LWF (Lagrangian wall film) is used to simulate the water film distribution and flow characteristics of train. Then the water film distribution and aerodynamic characteristics of high-speed train surface under different rainfall intensities were studied. The calculation results show that raindrops gather on the train surface to form water film under rainfall environment, and with the increase of rainfall time, the thickness and coverage range of water film expand, and the maximum thickness of water film can reach 4.95 mm. The average water film thickness of the train surface increases with rainfall intensity, which increases 3.26 times from 100mm/h to 500mm/h. The velocity of water film in the streamlined area of head car is larger, and the maximum velocity is 22.14m/s. The skin friction coefficient of high-speed train surface increases under rainfall condition. Compared with no rainfall condition, the average skin friction coefficient of train surface increases by 10.74% under rainfall intensity of 500mm/h. The head car positive pressure increases with the increase of rainfall intensity; with the increase of rainfall intensity, the drag coefficient of the head car increases.
Molecular cloning and functional analysis of Chinese bayberry MrSPL4 that enhances growth and flowering in transgenic tobacco
Authors: Wu Xiangqi , Zhang Shuwen , Yu Zheping , Sun Li , Liang Senmiao , Zheng Xiliang , Qi Xingjiang , Ren Haiying
Published: October 2022

Chinese bayberry (Myrica rubra) is an important tree in South China, with its fruit being of nutritional and high economic value. The early maturing varieties of Chinese bayberry are characterized by early flowering. In this study, early ripening (ZJ), medium ripening (BQ) and late ripening (DK) varieties were used as test materials, while young leaves in the floral bud morphological differentiation period were selected for transcriptome sequencing. A total of 4,538 differentially expressed genes were detected. Based on clustering analysis and comparisons with genes reportedly related to flowering in Arabidopsis thaliana, 25 homologous genes were identified. Of these, one was down-regulated in DK but up-regulated in ZJ and BQ, with the results also reflected in the relative expression determined by qRT-PCR. The gene contained the SBP domain and the target site of miR156, named MrSPL4. Primers were designed to clone the gene whose total length and the length of the CDS sequence were 1,664 bp and 555 bp respectively. An overexpression vector (35S:: 35S::MrSPL4-pCambia2301-KY) was then constructed and successfully transfected into tobacco to obtain MrSPL4-positive plants. In this case, the relative expression of MrSPL4 was up regulated by 3,862.0-5,938.4 times. The height of positive plants was also significantly higher than that of wild-type (WT) plants, with the bud stage occurring 12 days earlier. Altogether, the results indicated that the gene influenced growth and flowering, which provided a theoretical basis for the regulation of flowering in Chinese bayberry.
Analytic Solution to Isotropic Axisymmetric Cylinder Under Surface Loadings Problem Through Variational Principle
Authors: Sirsat Ajinkya Vishnu , Padhee Srikant Sekhar
Published: October 2022

Analysis of cylinders under axisymmetric loading is of great interest as it finds many practical application. In this work an attempt has been made to solve this problem through variational principle. The variational statement results in a set of coupled partial governing equation and associated boundary conditions. The solution has been derived after systematic decoupling of governing equation, application of separation of variables and use of Frobenius method. The resulting solution as demonstrated is capable of satisfying all the boundary conditions in an exact sense. The accuracy and efficiency of the presented solution have been validated for problems available in the literature and against three dimensional finite element simulations for isotropic homogeneous material. It is observed that the present solution not only has excellent agreement with three dimensional finite element analysis but also is generic in nature.
Postoperative Nonsteroidal Anti-inflammatory Drugs Do Not Increase Postoperative Anastomotic Leakages in Colorectal Surgery: A Meta-analysis
Authors: Mucilli Felice , Barone Mirko , Frontera Regina , Liouras Rita Vaia , Cappabianca Francesco , Serano Luca , Cannizzaro Paolo , Dell’Atti Ivan , Vetrugno Luigi , Maggiore Salvatore Maurizio
Published: October 2022

Background- Nonsteroidal anti-inflammatory drugs are cornerstones in multimodal analgesia and recent data suggest an association with an increased incidence of anastomotic leakage in surgical colorectal cancer patients. Objective- Aim of this systematic review and meta-analysis was to evaluate any effect of post-operative NSAIDs administration on the risk of anastomotic leakages and to carry out a scatter analysis between promoting dosages and fistulas. Data sources- Indexed and unindexed published articles from 1990 to 2022 were identified by electronic databases researches. Study selection- Two-arm studies about adult colorectal cancer patients undergoing surgery and assigned to postoperative non-steroidal anti-inflammatory drug-based analgesia (experimental cohorts) vs control ones. Intervention- Non-steroidal anti-inflammatory drug administration in the postoperative period. Endpoints- Primary endpoint was the evaluation of the incidence of anastomotic leakages (overall cumulative effect, subgroup pharmacological classes). In the second part of the analysis, a comparative analysis between drugs’ dosage and postoperative fistula was assessed. Results- According to PRISMA ® 2020 flow diagram, fourteen studies were included for a total of 36,330 enrolled patients (15,051 experimental vs 21,279 control) (Cohen’s k: 0.87). Overall postoperative anastomotic leakage incidence was 4.69%. NSAIDs do not increas rge risk of anastomotic leakage after colorectal surgery (OR: 1.24, 95%CI: 0.93–1.66; p = 0.14). At subgroup analysis, non-selective NSAIDs resulted safer than selective ones (OR: 0.51, 95% CI: 0.40–0.66, p < 0.001). No differences among drugs and fistula risk was found (Diclofenac vs Ibuprofen vs Ketorolac: OR: 1.99, p = 0.09 vs OR: 0.91, p = 0.82 vs OR: 1.14, p = 0.63). At the scatter plot analysis, excellent pharmacological safety profiles at maximal dosage for all the molecules investigated was reported. Limitations- Four studies lacked an exhaustive methodological report on protocols and dosages. Subgroup analysis for selected cohorts for type of drug administration could lead to a type 2 statistical error. Conclusions- Postoperative administration of NSAIDs in colorectal cancer surgery is safe and does not increase the risk for postoperative anastomotic dehiscences. However, selective drugs could predispose to dehiscence when compared to non-selective ones.
Evaluation of financial literacy of rural households: a case study of tomato farmers in Ghana
Authors: AIDOO-MENSAH DANIEL , ANANG SAMUEL AFOTEY , BOTCHWAY JACK
Published: October 2022

Financial literacy has been described as an important a mix of knowledge, skill and attitude of individuals, households and even whole nations towards financial matters. It helps to make informed financial decisions, thereby ensuring financial stability, vis-à-vis, economic well-being of the decision maker. Globally, studies in the area of financial literacy have been conducted with the aim of measuring the level of financial literacy of respondents. The results of most of these studies have brought to the fore the poor level of financial literacy among even educated people. The present study evaluates the financial literacy of 562 tomato farmers randomly sampled from three key tomato growing regions in Ghana. Their financial literacy level was evaluated based on their opinions on five basic financial information regularly asked questions by OECD’s International Network on Financial Education. To ascertain the level of agreement among the respondents in their rankings of the financial literacy items, Kendall’s Coefficient of Concordance (Kendall’s W) was estimated. A ranking analysis of the respondents’ responses on the basic financial information indicated that “It is important that one should have a regular savings plan” was ranked as the most important information on financial literacy. Finally, by means of a binary logistic regression, the study went further to determine the tomato farmers’ view on this all-important financial management tool premised on the fact that they viewed financial literacy as important to them thus availing themselves for financial literacy programmes to enhance their financial skills. The results of the binary logistic regression indicate that income diversification significantly influenced a farmer’s view of financial literacy being important whilst farm size and years of education had negative but significant relationship on their view. The study has therefore confirmed the lack of interest of financial literacy among rural households particularly due to their low level of education.
Evolution of acquired humoral immunity after full vaccination against SARS-CoV-2. IgG levels in healthcare workers at 6 and 9 months
Authors: Delicado-Useros María Victoria , Navarro-Rodenas Esther , Sánchez-Onrubia Indalecio Miguel , Ortega-Martínez Carmen , Alfaro-Espín Antonia , Pérez-Serra Juan Daniel , García-Alcaraz Francisco , Lozano-Serra Julia , Robles-Fonseca Lorena , Pérez-Domenech Teresa
Published: October 2022

Background
The COVID-19 pandemic continues to be a major worldwide health problem. The present study aims to contribute to surveillance of the immune and clinical response of vaccines to SARS-CoV-2.
Methods
Observational study of medication on acquired immunity and effectiveness of vaccines. Population: 620 workers in the health service of Almansa (Spain). Representative sample of 150 individuals. Sociodemographic, clinical, and epidemiological data and samples were recorded to determine anti- SARS-CoV2 serum IgG levels 6 and 9 months after vaccination with Pfizer.
Results
Mean age 46.45 years; 76% women; 85.1% working in a hospital. 19.3% had had COVID-19 in the year prior to vaccination. 96.7% were fully vaccinated with Pfizer/BioNTech. At 6 months, 100% seropositivity and mean IgG levels of 3017.2 AU/ml. Significant variations in IgG levels in individuals with prior COVID-19 infection and smokers. At 9 months, 99.3% remained seropositive; 2.8% infected after vaccination. The repeated measures analysis showed a difference in means of 669.0 AU/ml (significant decrease in IgG levels of 28.9%).
Conclusion
Antibody levels remained positive 6 and 9 months after vaccination, although IgG levels were found to decay.