bluuebunny/crossref_metadata_2025 huggingface dataset:
Assessing the relationship between hypospadias risk and parental occupational exposure to potential endocrine-disrupting chemicals
Authors: Das Deepjyoti , Dutta Hemonta Kumar , Borbora Debasish , Brahma Rocket Chandra , Das Jitu Mani
Published: December 2022

Objective

The association between periconceptional parental exposure to endocrine-disrupting chemicals (EDCs) and hypospadias remains inconclusive and controversial. Therefore, we conducted a hospital-based retrospective study to assess the relationship between hypospadias risk and parental occupational exposure to potential EDCs.

Methods

Incident cases (n=73) were boys between 0 and 14 years diagnosed with hypospadias with no micropenis or cryptorchidism. Controls (n=146) were an age-matched group of boys without any congenital malformations, inguinal hernia, nephrological, urological and genital disorders. Their selection was independent of exposures to EDCs. Data on parental occupation and sociodemographic variables were collected using a structured questionnaire. We evaluated parental occupational exposures using a previously validated job-exposure matrix (JEM) for EDCs.

Results

In our case–control study, 30.1% of all pregnancies had likely exposure to potential EDCs. The most prevalent occupations conferring possible exposure were related to activities on farms. Maternal and paternal occupational exposure to potential EDCs significantly increased the risk of mild hypospadias than moderate-to-severe hypospadias (OR=6.55 vs OR=4.63). Among various categories, parental occupational exposure to pesticides was associated with at least a twofold increased risk of hypospadias. Maternal EDC exposure during the first trimester significantly increased the risk of bearing a hypospadiac child (OR=4.72 (95% CI 2.10 to 10.60)).

Conclusion

This study suggests that EDCs are a risk factor for hypospadias through occupational exposure during fetal life.
Quantum cosmology of the flat universe via closed real-time path integral
Authors: Wang Hong , Wang Jin
Published: December 2022

Quantum cosmology is crucial to understand the evolution of the early universe. Despite significant progress, challenges still remain. For example, the role of time in quantum cosmology is unclear. Furthermore, the influence of the environment on the evolution of the quantum universe is challenging. In this work, we studied the evolution of the quantum universe non-perturbatively using the closed real-time path integral. The environments coupled to the quantum universe being considered are the radiation, the non-relativistic matter, or the dark matter. We evaluated the influence functional of the massless scalar field coupled with the flat FRW universe. We studied the evolution of the quantum universe by setting the initial state of spacetime as a Gaussian wave packet. In different scenarios, we show that the classical trajectory of the universe is consistent with the quantum evolution of the wave packet. The coherence, the absolute quantum fluctuation and the Gibbs entropy all monotonically increase with time, yet the relative quantum fluctuation decreases with time. We show that for a given size of the radiation dominated universe, the lower temperature corresponds to a more quantum universe. We find that the minimal coupling of the free massless scalar field with the flat FRW spacetime generally gives rise to the memory characterized via non-Markovian correlations. Finally, we show that under higher radiation temperatures, a small universe has a higher chance of a transition to a bigger universe.
Reflected entropy in Galilean conformal field theories and flat holography
Authors: Basak Jaydeep Kumar , Chourasiya Himanshu , Raj Vinayak , Sengupta Gautam
Published: December 2022

We obtain the reflected entropy for bipartite states in a class of $$(1+1)$$

(
1
+
1
)

-dimensional Galilean conformal field theories $$(GCFT_{1+1})$$

(
G
C
F

T

1
+
1

)

through a replica technique. Furthermore we compare our results with the entanglement wedge cross section (EWCS) obtained for the dual (2 + 1) dimensional asymptotically flat geometries in the context of flat holography. We find that our results are consistent with the duality between the reflected entropy and the bulk EWCS for flat holographic scenarios.
The way to generating sub-femtosecond pulse trains with high-order stimulated Raman scatterings
Authors: Zhang Chuan , Zhou Xiaohua , Wen Yanni , He Yingying
Published: December 2022

The generation of ultrashort pulses is the key to exploring the dynamic behaviors of matter on ever-shorter timescales. Sub-femtosecond pulses can be used to explore atomic-scale electron motion which can reveal the nature of changes in chemical reactions and the function of biological systems. Recent developments have shown that sub-2-fs pulse trains can be produced in an experiment through molecular modulation. In this paper, we experimentally demonstrate the potential of yielding sub-femtosecond pulse trains with eight or more high-order stimulated Raman scattering components; and report the current bottleneck of generating sub-femtosecond pulse trains via molecular modulation.
Research on the structural design and pentamodal property of three-dimensional multilayer cylindrical pentamode metamaterials for tuning acoustic waves
Authors: Qin Yao , Wang Xue , Wang Qifu , Cai Chengxin
Published: December 2022

Pentamode metamaterial (PM) is an artificial solid form metamaterial with fluid characteristics. In this paper, a three-dimensional (3D) PMs based on multilayer cylindrical elements are proposed for increasing tunable structure parameters, obtaining great pentamodal property, reducing band gap frequency and decreasing connection overlap areas of elements. Compared with the PMs with double-cone elements, under the same parameters, the lower edge frequency of the single-mode band gaps can be reduced by 33.2%, the maximum value of figure of merit can be increased by 84.8% and the phononic band gaps can be reduced by 73.9%.
NEW FRACTAL SOLITON SOLUTIONS FOR THE COUPLED FRACTIONAL KLEIN–GORDON EQUATION WITH β-FRACTIONAL DERIVATIVE
Authors: WANG KANGLE
Published: December 2022

In this paper, we derive some novel fractal soliton solutions of the coupled fractional Klein–Gordon equation with the [Formula: see text]-fractional derivative via two efficient methods, which are fractal functional variable method and fractal sech-function method. The two new mathematical schemes are quite concise and effective, and then numerous new exact fractal soliton solutions of other nonlinear fractal evolution equations can be obtained. Finally, some 3D figures are sketched to describe these new fractal soliton solutions.
Unidirectional Information Flow and Positive Divisibility are Nonequivalent Notions of Quantum Markovianity for Noninvertible Dynamics
Authors: Rivas Ángel
Published: December 2022

We construct a dynamical map which is not positive divisible and does not present information backflow either (as measured by trace norm quantifiers). It is formulated for a qutrit system undergoing noninvertible dynamics. This provides an evidence that the two definitions of quantum Markovianity based on the absence of information backflow and positive divisibility are nonequivalent for general noninvertible dynamical maps.
Random Walk on Quantum Blobs
Authors: Jadczyk Arkadiusz
Published: December 2022

We describe the action of the symplectic group on the homogeneous space of squeezed states (quantum blobs) and extend this action to the semigroup. We then extend the metaplectic representation to the metaplectic (or oscillator) semigroup and study the properties of such an extension using Bargmann-Fock space. The shape geometry of squeezing is analyzed and noncommuting elements from the symplectic semigroup are proposed to be used in simultaneous monitoring of noncommuting quantum variables — which should lead to fractal patterns on the manifold of squeezed states.
On Quasi-Inversion of Quantum Channels in 2 and in Higher Dimensions
Authors: Karimipour Vahid
Published: December 2022

We review the concept of the quasi-inverse of qubit channels and of higher dimensional channels. Quasi-inverse is a channel which when concatenaded to the original channel, increases its average fidelity in an optimal way. For qubit channels, we fully characterize the quasi-inverse, while for higher dimensional channels, we prove general theorems and provide bounds for the increased average fidelity. Nevertheless, explicit examples are given when exact quasi-inverses can be found.
QiCells: A Modular RFSoC-based Approach to Interface Superconducting Quantum Bits
Authors: Gebauer Richard , Karcher Nick , Güler Mehmed , Sander Oliver
Published: December 2022

Quantum computers will be a revolutionary extension of the heterogeneous computing world. They consist of many quantum bits (qubits) and require a careful design of the interface between the classical computer architecture and the quantum processor. For example, even single nanosecond variations of the interaction may have an influence on the quantum state. Designing a tailored interface electronics is therefore a major challenge, both in terms of signal integrity with respect to single channels, as well as the scaling of the signal count.

We developed such an interface electronics, an RFSoC-based qubit control system called QiController. In this article, we present the modular FPGA firmware design of our system. It features so-called digital unit cells, or QiCells. Each cell contains all the logic necessary to interact with a single superconducting qubit, including a custom-built RISC-V-based sequencer. Synchronization and data exchange between the cells is facilitated using a special star-point structure. Versatile routing and frequency-division multiplexing of generated signals between QiCells and converters are also supported. High-level programmability is provided using a custom Python-based description language and an associated compiler. We furthermore provide the resource utilization of our design and demonstrate its correct operation using an actual superconducting five-qubit chip.
Lymphangioleiomyomatosis: a metastatic lung disease
Authors: Kundu Nandini , Holz Marina K.
Published: December 2022

Lymphangioleiomyomatosis (LAM) is a rare disease affecting women, caused by somatic mutations in the TSC1 or TSC2 genes, and driven by estrogen. Similar to many cancers, it is metastatic, primarily to the lung. Despite its monogenetic nature, like many cancers, LAM is a heterogeneous disease. The cellular constituents of LAM are very diverse, including mesenchymal, epithelial, endothelial, and immune cells. LAM is characterized by dysregulation of many cell signaling pathways, distinct populations of LAM cells, and a rich microenvironment, in which the immune system appears to play an important role. This review delineates the heterogeneity of LAM and focuses on the metastatic features of LAM, the deregulated signaling mechanisms and the tumor microenvironment. Understanding the tumor-host interaction in LAM may provide insights into the development of new therapeutic strategies, which could be combinatorial or superlative to Sirolimus, the current U.S. Food and Drug Administration-approved treatment.
Cartilage extracellular matrix-derived matrikines in osteoarthritis
Authors: Rapp Anna E. , Zaucke Frank
Published: December 2022

Osteoarthritis (OA) is among the most frequent diseases of the musculoskeletal system. Degradation of cartilage extracellular matrix (ECM) is a hallmark of OA. During the degradation process, intact/full-length proteins and proteolytic fragments are released which then might induce different downstream responses via diverse receptors, therefore leading to different biological consequences. Collagen type II and the proteoglycan aggrecan are the most abundant components of the cartilage ECM. However, over the last decades, a large number of minor components have been identified and for some of those, a role in the manifold processes associated with OA has already been demonstrated. To date, there is still no therapy able to halt or cure OA. A better understanding of the matrikine landscape occurring with or even preceding obvious degenerative changes in joint tissues is needed and might help to identify molecules that could serve as biomarkers, druggable targets, or even be blueprints for disease modifying drug OA drugs. For this narrative review, we screened PubMed for relevant literature in the English language and summarized the current knowledge regarding the function of selected ECM molecules and the derived matrikines in the context of cartilage and OA.
Cardioprotective Effects of Aconite in Isoproterenol-Induced Myocardial Infarction in Rats
Authors: Xing Ziwei , Yang Chao , He Junyao , Feng Yaqian , Li Xu , Peng Cheng , Li Dan
Published: December 2022

Background. Myocardial infarction (MI) is a severe clinical condition caused by decreased or complete cessation of blood flow to a portion of the myocardium. Aconite, the lateral roots of Aconitum carmichaelii Debx., is a well-known Chinese medicine for treatment of heart failure and related cardiac diseases. The present study is aimed at investigating the cardioprotective effect of aconite on isoproterenol- (ISO)- induced MI. Methods. The qualitative analysis of aqueous extracts from brained aconite (AEBA) was conducted by HPLC. A rat model of MI induced by ISO was established to examine the effects of AEBA. The cardiac function was assessed by echocardiography. The serum levels of SOD, CK-MB, cTnT, and cTnI were detected to estimate myocardial injury. The pathological changes of heart tissue were evaluated by 2,3,5-triphenyltetrazolium chloride (TTC) staining, hematoxylin-eosin (HE) staining, and Masson’s trichrome staining. The expressions of abnormal vascular remodeling and hypoxia-related components and the levels of inflammation-associated genes and proteins were detected by RT-qPCR, western blotting, and immunofluorescence. Results. The contents of benzoylaconine, benzoylmesaconine, benzoylhypacoitine, and hypaconitine in AEBA were 1.35 μg/g, 37.35 μg/g, 57.10 μg/g, and 2.46 μg/g, respectively. AEBA obviously improved heart function through promoting echocardiographic parameters, radial strain, and circumferential strain. The data of TTC staining, HE staining, and Masson’s trichrome staining disclosed that AEBA could significantly reduce infarct size, inhibit inflammatory cell infiltration, and decrease the myocardial fibrosis. Moreover, AEBA distinctly suppressed the serum levels of SOD, MDA, CK-MB, cTnT, and cTnI in ISO-induced rats. The results of RT-qPCR indicated that AEBA inhibited the expressions of hypoxia- and inflammation-related genes, including VEGF, PKM2, GLUT-1, LDHA, TNF-α, IL-1β, IL-6, and COX2. In addition, the western blotting and immunofluorescence analyses further confirmed the results of RT-qPCR. Conclusion. In summary, our results indicate that the AEBA could improve ISO-induced myocardial infarction by promoting cardiac function, alleviating myocardial hypoxia, and inhibiting inflammatory response and fibrosis in heart tissue.
Study on the Stage Characteristics of Noise Dispersion in the Deformation Evolution of Red Sandstone
Authors: Song Yimin , Yuan Deshun , Zhang Junhui , Xu Hailiang , An Dong , Ren He
Published: December 2022

The uniaxial compression experiment of red sandstone is observed simultaneously by using acoustic emission and digital speckle correlation methods. The deformation evolution of red sandstone is divided into microfracture random expansion stage, deformation localization stage, subinstability stage, and instability failure stage. Green’s function and dispersion curve of each stage are obtained from the noise data picked up by acoustic emission equipment, and the dispersion characteristics of each evolution stage are analyzed. The results show the following: (1) In the stage of random propagation of microcracks, the noise in the low frequency range passes through at a higher phase velocity, the phase velocity changes periodically, the correlation coefficient is high at the initial time, and the variation trend of frequency dispersion curve is relatively consistent. (2) In the deformation localization stage, the frequency range without zero phase velocity moves to the high frequency range, and the phase velocity changes periodically. (3) In the subinstability stage, dense phase velocity zeros appear on the dispersion curve image, the dispersion curve tends to be disordered, various indicators change obviously, and the correlation coefficient decreases rapidly. (4) In the unstable failure stage, the fracture evolution is completed, and the variation trend of each index of the frequency dispersion curve is consistent. (5) The size and difference of the sensitive kernel function of the two layers are related to the evolution region of the fracture. The sensitivity kernel value of the medium layer where the fracture evolves is high, and the longer the evolution time, the greater the difference.
Shenfu Injection Protects Brain Injury in Rats with Cardiac Arrest through Nogo/NgR Pathway
Authors: Deng Haixia , Tang Zhanhong , Tuo Peng , Wu Ruihua , Jia Si , Zhao Xuan , Huang Deqing , Gao Yuguang , Lan Zhou
Published: December 2022

The effect of Shenfu injection on brain injury after cardiac arrest (CA) and cardiopulmonary resuscitation (CPR) along with the underlying mechanism of axonal regeneration was explored. CA/CPR model in rats was established for subsequent experiments. A total of 160 rats were randomly divided into sham group, model group, conventional western medicine (CWM) group, Shenfu group, and antagonist group (

n
=
32

per group). After 3 hours, 24 hours, 3 days, and 7 days of drug administration, the modified Neurological Severity Score tests were performed. The ultrastructure of the brain and hippocampus was observed by electron microscopy. Real-time quantitative polymerase chain reaction (PCR), western blotting, and immunohistochemistry were used to detect Nogo receptor (NgR) expression in the hippocampus and cerebral cortex, and Nogo–NgR expression in CA/CPR model. Neurological deficits in the model group were severe at 3 hours, 24 hours, 3 days, and 7 days after the recovery of natural circulation, whereas the neurological deficits in CWM, antagonist, and Shenfu group were relatively mild. The ultrastructure of neuronal cells in Shenfu group had relatively complete cell membranes and more vesicles than those in the model group. The results of PCR and western blotting showed lower messenger ribonucleic acid and protein expression of NgR in Shenfu group than the model group and CWM group. Immunohistochemical examination indicated a reduction of Nogo–NgR expression in Shenfu group and antagonist group. Our results suggested that Shenfu injection reduced brain injury by attenuating Nogo–NgR signaling pathway and promoting axonal regeneration.
Extraction and Analysis of Spatial Feature Data of Traditional Villages Based on the Unmanned Aerial Vehicle (UAV) Image
Authors: Teng Zun , Li Chuntao , Zhao Wenjing , Wang Zuxiang , Li Ruonan , Zhang Lang , Song Yuqing
Published: December 2022

In the process of the evolution of urban-rural spatial patterns, traditional village forms have been seriously eroded and destroyed, resulting in the gradual loss of garden feature elements and the blurring of spatial features. Facing these problems, accurate and efficient acquisition of relevant data becomes the key to traditional village conservation. We take the typical Huizhou Shuikou garden Tangmo village as an example and conduct a study on how to use UAV aerial images to extract spatial feature data. Firstly, the UAV was used to acquire aerial images of the study area through a predefined mission. Then, the image data are processed by using structure from motion (SfM) software to obtain digital surface model (DSM), digital orthophoto map (DOM), point cloud, and 3D model. Finally, the produced spatial data are applied to the spatial feature extraction analysis study. The results show the following: (1) the data produced by UAV aerial images have a horizontal accuracy of 0.034 m and a vertical accuracy of 0.039 m, which meet the requirements of traditional village spatial data collection. (2) The results of spatial feature elements and terrain feature extraction show that the 3D model and DSM can accurately extract and analyze the micro and macro spatial feature of traditional villages. (3) By using the cloth simulation filtering (CSF) to extract point clouds of buildings and streets, and after statistical analysis, we could quickly obtain their spatial features. Based on the spatial data obtained by using UAV, the study achieves the accurate collection of Tangmo DSM, DOM, 3D model, and spatial feature data and forms a method of data collection, processing and spatial feature extraction. The results of the study can provide a scientific basis for data collection on the spatial features of other cultural heritages and the conservation of traditional villages.
Ag85A, As an S2 Vaccine Carrier, Reduces the Toxicity of the S2 Vaccine and Enhances the Protective Ability of Mice against Brucella
Authors: Zhang Shuai , Chao Lumen , She Lemuge , Sui Humujile , Niu Huaxin , Chen Zeliang , Li Xiangyang , Zhai Jingbo
Published: December 2022

Brucella is a globally distributed zoonotic disease that can cause abortion and changes in immune function in humans and animals. At present, there is no good treatment plan for Brucella, and animals can only be treated harmlessly once they become ill, resulting in huge economic losses. Therefore, the prevention of Brucella infection is a very crucial step. Although a variety of Brucella vaccines have been widely used, they have varying degrees of shortcomings. For example, some Brucella vaccines have residual virulence, which leads to the emergence of Brucella in animals during the immunization process. Bacillus infection and other conditions occur. To further reduce the toxicity of the Brucella vaccine and enhance its protective effect on animals, this study used Antigen 85A (Ag85A) as a carrier of the Brucella vaccine to fuse with the Brucella S2 vaccine. The results of the study found that the S2-Ag85A oral Brucella vaccine could effectively reduce the toxicity residue of the S2 vaccine, stimulate the mice to produce a better immunogenic response, and effectively activate the expression levels of Brucella heterozygous IgG1 and IgG2a. Experiments have shown that the expression of IFN-γ in the peripheral blood serum and spleen of mice is significantly increased, and the expression levels of IL-1β, TNF-α, and IL-6 are significantly reduced, which may indicate that S2-Ag85A oral Brucella vaccine could induce the expression of IFN-γ, thus downregulating the expression levels of IL-6 and TNF-α in the spleen tissue. The above results indicate that the S2-Ag85A oral vaccine is an effective attenuated vaccine for preventing Brucella infection.
Pseudoaneurysm following Two-Stage Hip Revision with Fasciotomy
Authors: Pollock Jordan R. , McQuivey Kade S. , Braithwaite Collin L. , Swanson Jennifer , Bingham Joshua S.
Published: December 2022

In the setting of total hip arthroplasty (THA), pseudoaneurysms are extremely rare and can be difficult to diagnose, as clinical symptoms can mimic symptoms of other more common complications, such as periprosthetic joint infection, hematoma, and nerve damage. We present a case of a 69-year-old male with a history of slipped capital femoral epiphysis 56 years prior and subsequent right THA. The right hip primary arthroplasty was subsequently complicated by multiple dislocations and recurrent prosthetic joint infections. The most recent infection was treated with debridement, antibiotics, and implant retention (DAIR) in 2017. The patient later presented in 2019 with right thigh pain. Upon further analysis, he was diagnosed with Streptococcus bovis positive periprosthetic joint infection. The patient underwent a two-stage revision of the hip using an antibiotic spacer. Two weeks following the second stage, he presented with a sudden onset of uncontrolled atrial fibrillation with rapid ventricular response and a low hemoglobin. The computed tomography scan revealed a large hematoma involving both the anterior and posterior thigh compartments with lab markers that were questionable for infection. An operation to remove the hematoma revealed no purulence, and a large pulsatile pseudoaneurysm on the posterolateral aspect at the mid femur was found. A sharp bone fragment was noted next to the pseudoaneurysm. The pseudoaneurysm was repaired by a vascular surgeon, and the bone fragment was removed. Following this procedure, the patient developed a subsequent periprosthetic joint infection requiring a double DAIR procedure six weeks following the pseudoaneurysm repair and is now on chronic antibiotic suppression. Orthopedic surgeons should be aware of the potential for pseudoaneurysm in the setting of total joint arthroplasty when treating a postsurgical hematoma of sudden onset.
Solving Partial Integro-Differential Equations via Double Formable Transform
Authors: Ghazal Bayan , Saadeh Rania , Sedeeg Abdelilah K.
Published: December 2022

In this study, we present a new double integral transform called the double formable transform. Several properties and theorems related to existing conditions, partial derivatives, the double convolution theorem, and others are presented. Additionally, we use a convolution kernel to solve linear partial integro-differential equations (PIDE) by using the double formable transform. By solving numerous cases, the double formable transform’s ability to turn the PIDE into an algebraic equation that is simple to solve is demonstrated.
Prospect Theory-Based Two-Sided Satisfied and Stable Matching Mechanism for the Shared Parking Slots Problem
Authors: Xiao Yun , Wang Guangmin , Xu Meng
Published: December 2022

The contradiction between the dramatic increase in the aggregate number of automobiles and the short supply of parking spaces leads to parking difficulties. Sharing mode helps improve the efficiency of existing parking spaces, increase resource utilization, and alleviate the difficulty of parking. This paper focuses on the matching mechanism in the shared parking slots problem, which involves three agents: shared parking suppliers, shared parking demanders, and shared parking platform. We propose a prospect theory-based two-sided satisfied and stable matching model (PT-TSSM) with two objectives to maximize the satisfaction degree of both shared parking demanders and shared parking suppliers. Numerical experiments are illustrated to demonstrate the efficiency of the proposed model. Moreover, the PT-TSSM model is compared with the other two shared parking mechanisms. The proposed model considers the satisfaction degrees of both shared parking demanders and suppliers, while first book first serve (FBFS) cares only one side of the participants. And compared with deferred acceptance (DA), our model not only takes two-sided stable matching into account but also considers the satisfaction degree of all the demand and supply participants, which obtain a two-sided satisfied and stable matching scheme.
Network-Based Modeling of the Molecular Topology of Fuchsine Acid Dye with Respect to Some Irregular Molecular Descriptors
Authors: Ullah Asad , Shamsudin  , Zaman Shahid , Hamraz Anila , Saeedi Ghulamullah
Published: December 2022

Fuchsine acid is one of the supramolecular dyes used in Masson’s trichrome stain and has enormous applications in histology. It is also used in Van Gieson’s method with picric acid to show red collagen fibers and in Masson’s trichrome to show smooth muscle in contrast to collagen. In addition to these, it has several other important applications in electronic fields and photonic devices as an organic semiconductor. Therefore, it is of utmost importance to investigate and predict the complex molecular topology of fuchsine acid, which serves as a foundation for the link with its physicochemical properties. In this article, the supramolecular sheet of fuchsine acid is modeled topologically based on the edge partition, and closed formulae are derived for some of its important irregular molecular descriptors, with the ultimate object of throwing some light on the effectiveness of the computed molecular descriptors for QSAR and QSPR analyses.
Extraction and Identification of Antioxidant Ingredients from Cyclocarya paliurus (Batal.) Iljinsk Using UHPLC-Q-Orbitrap-MS/MS-Based Molecular Networking
Authors: Tong Yingpeng , Li Xin , Zhu Ziping , Wang Ting , Zhou Qi , Li Na , Xie Zhenda , Jiang Chunxiao , Li Junmin , Wang Jianxin
Published: December 2022

Cyclocarya paliurus (Batal.) Iljinskaja (LCP) leaves have been widely employed in food and traditional medicine for treating hyperlipidaemia and its complications, possibly owing to their antioxidant properties. The aim of the present study is to identify the chemical ingredients of antioxidant extracts from LCP by using UHPLC-Q-Orbitrap-MS/MS-based molecular networking, a very recent and useful tool for annotation of chemical constituents in mixtures. The extraction conditions of antioxidant extracts from LCP were optimised by single-factor analysis and response surface methodology (RSM). The optimised conditions were a methanol concentration of 32%, a liquid-to-solid ratio of 0.4 ml/mg, an extraction temperature of 25°C, and an extraction time of 32 min. Under these conditions, the antioxidant yield was 516.20 ± 28.52 μmol TE/ml. The main active ingredients in the antioxidants were identified by UHPLC-Q-Exactive Orbitrap-MS-based molecular networking. In total, 42 compounds were identified, including 20 flavonoids, 16 quinic acid derivatives, 4 caffeoyl derivatives, and 2 coumaroyl derivatives. The findings of the present work suggest that LCP could be a suitable source of natural antioxidant compounds, which might be applicable in the development of potential pharmaceutical drugs targeting diseases related to oxidative stress.
Flora da Serra do Cipó, Minas Gerais: Costaceae
Authors: Antar Guilherme Medeiros , Sano Paulo Takeo
Published: December 2022

O estudo de Costaceae integra o projeto “Flora da Serra do Cipó, Minas Gerais, Brasil”. A família está representada na Serra do Cipó por duas espécies: Chamaecostus subsessilis (Nees & Mart.) C.D.Specht & D.W.Stev. e Costus spiralis (Jacq.) Roscoe. São apresentadas chaves para os gêneros, descrições e ilustrações, além de comentários sobre distribuição geográfica e aspectos ecológicos das espécies.
As subtribos Laeliinae e Ponerinae (Epidendroideae, Orchidaceae) No Parque Estadual do Ibitipoca, Minas Gerais, Brasil
Authors: Nardy Camila , Furtado Samyra Gomes , Salimena Fátima Regina Gonçalves , Menini Neto Luiz
Published: December 2022

O Parque Estadual do Ibitipoca (PEIB) está localizado a sudeste na zona da mata mineira, nos municípios de Bias Fortes, Santa Rita de Ibitipoca e Lima Duarte. Destaca-se por apresentar um mosaico de vegetação com o campo rupestre como fisionomia principal. É um dos parques mais visitados do país e sofre, por isso, uma intensa ação antrópica. Foram encontradas na área 23 espécies de Laeliinae e uma de Ponerinae (Isochilus linearis (Jacq.) R.Br.). O gênero Epidendrum é o mais rico em espécies (11 spp.), seguido por Prosthechea (3 spp.), Cattleya, Hoffmanseggella e Isabelia (2 spp. cada), Encyclia, Hadrolaelia, Isochilus e Scaphyglottis (1 sp. cada). Entre os estudos realizados com as duas subtribos em Minas Gerais, a Serra Negra e a Reserva Particular do Patrimônio Natural do Caraça são as localidades que apresentam o número de espécies similar ao PEIB, embora ambas com maior extensão. Dentre as espécies listadas, seis encontram-se enquadradas em alguma categoria de ameaça de extinção em Minas Gerais: Cattleya bicolor, C. loddigesii, Hadrolaelia coccinea, Hoffmannseggella caulescens, H. crispata e Isabelia violacea. No Livro Vermelho da Flora do Brasil estão citadas Hoffmannseggella caulescens e Isabelia virginalis. Foi encontrado um novo registro para o PEIB, Epidendrum aff. filicaule na borda da nanofloresta nebular. São apresentadas chave de identificação, descrições, ilustrações e comentários sobre forma de vida e particularidades morfológicas, distribuição geográfica e habitat.
Flora da Serra do Cipó, Minas Gerais: Bixaceae
Authors: Antar Guilherme Medeiros , Sano Paulo Takeo
Published: December 2022

O estudo de Bixaceae está incluído no projeto “Flora da Serra do Cipó, Minas Gerais, Brasil”. A família está representada na Serra do Cipó pela espécie Cochlospermum regium (Mart. ex Schrank) Pilg. São apresentadas descrição, ilustrações e comentários sobre a distribuição geográfica e aspectos ecológicos dessa espécie.
Ericaceae do Parque Estadual da Serra do Papagaio, Minas Gerais, Brasil
Authors: Cabral Andressa , Romão Gerson O. , Salimena Fátima Regina Gonçalves , Menini Neto Luiz
Published: December 2022

O Parque Estadual da Serra do Papagaio está localizado na Serra da Mantiqueira, sul de Minas Gerais, abrigando um importante remanescente de Floresta Atlântica. Possui uma área de 22.917 ha., dos quais cerca de 50% apresenta altitudes acima de 1.800m. O levantamento florístico foi realizado entre os anos de 2009 e 2013 e os espécimes coletados foram depositados no Herbário Leopoldo Krieger (CESJ), da Universidade Federal de Juiz de Fora. O objetivo deste estudo foi apresentar o tratamento taxonômico para Ericaceae nesta unidade de conservação. Foram registradas 10 espécies pertencentes a três gêneros, sendo Gaultheria e Gaylussacia os mais ricos, ambos representados por quatro espécies cada, e Agarista representado por apenas duas espécies. São apresentadas chaves de identificação, descrições das espécies, ilustrações de caracteres diagnósticos e comentários de distribuição geográfica, ecológicos e taxonômicos.
Sampling plan and methodological aspects: a household healthcare survey in Piauí
Authors: Rodrigues Lays Arnaud Rosal Lopes
Published: December 2022

Corrige o artigo: 10.11606/s1518-8787.2021055003441
In the article “Sampling plan and methodological aspects: a household healthcare survey in Piauí”, DOI https://doi.org/10.11606/s1518-8787.2021055003441, published onthe Revista de Saúde Pública.2021;55:118, on page 7, in the Table 2, the RSP corrects theheader of third and eighth column.Where it reads:172 interviewed households.It should read:Interviewed households
Idade gestacional, crescimento intrauterino e composição corporal aos 11 anos de idade
Authors: Bortolotto Caroline Cardozo , Santos Iná da Silva dos , Vaz Juliana dos Santos , Matijasevich Alicia
Published: December 2022

OBJETIVO: Avaliar a associação da idade gestacional (IG) e crescimento intrauterino com a composição corporal aos 11 anos de idade. MÉTODO: Análise de dados da coorte de nascimentos de Pelotas de 2004, cujos desfechos foram massa gorda (MG, kg), índice de massa gorda (IMG, kg/m2), massa livre de gordura (MLG, kg), índice de massa livre de gordura (IMLG, kg/m2) – medidos por pletismografia por deslocamento de ar –, e índice de massa corporal para idade (IMC/Idade, escore-Z). Sendo as exposições de interesse o índice gestacional (IG) de nascidos com menos de 33 semanas, de 34 a 36 e de 37 a 41, e crescimento intrauterino categorizado em pequeno para a idade gestacional (PIG), adequado (AIG) e grande (GIG). Para comparar médias, utilizou-se análise de variância e, para avaliar a força de associação, regressão linear. As análises foram ajustadas de acordo com variáveis coletadas ao nascer, como renda familiar mensal, características maternas – escolaridade, idade, índice de massa corporal (IMC) pré-gestacional, ganho de peso na gestação, tabagismo na gestação, tipo de parto e paridade – e características dos adolescentes – cor da pele e peso ao nascer. Para análise, o MG e o IMG sofreram transformação logarítmica devido a assimetria dos dados. RESULTADOS: Foram analisados 3.401 adolescentes, entre meninos e meninas nascidos com menos de 33 semanas, com médias de MG e MLG menores que as dos nascidos(as) a termo. Porém, nas análises ajustadas, não houve associação entre IG e qualquer um dos desfechos em ambos os sexos. Meninos GIG apresentaram IMG 10,5% maior (p = 0,026) e +0,3 escore-Z de IMC/Idade (p = 0,019) em relação aos AIG, e meninas GIG apresentaram +0,3 kg/m2 de IMLG (p = 0,039) do que as AIG. CONCLUSÃO: A IG não se associou à composição corporal aos 11 anos. Entretanto, meninos GIG apresentaram maiores IMG e escore-Z de IMC/Idade e meninas GIG, maior IMLG, quando comparados aos AIG.
Tratamentos utilizados por portadores de DPOC no Brasil: Pesquisa Nacional de Saúde, 2013
Authors: Marques Gabriela Ávila , Oliveira Paula Duarte de , Montzel Marina , Menezes Ana Maria Baptista , Malta Deborah Carvalho , Sardinha Luciana Monteiro Vasconcelos , Wehrmeister Fernando César
Published: December 2022

OBJETIVO: Estimar a prevalência dos tratamentos utilizados para o manejo da doença pulmonar obstrutiva crônica (DPOC) na população adulta brasileira. MÉTODOS: Estudo transversal de base populacional com dados oriundos da Pesquisa Nacional de Saúde de 2013, incluindo indivíduos com 40 anos ou mais, com diagnóstico médico autorreferido de DPOC, bronquite crônica e/ou enfisema, os quais foram questionados sobre tratamentos utilizados para o manejo da doença. RESULTADOS: Foram entrevistados 60.202 adultos, dos quais 636 tinham 40 ou mais anos de idade e haviam referido diagnóstico médico de DPOC, enfisema ou bronquite crônica. Menos da metade (49,4%) da população diagnosticada relatou utilizar algum tipo de tratamento, havendo diferenças quanto à macrorregião do país (Sul 53,8% – Nordeste 41,2%, p = 0,007). O tratamento medicamentoso foi o mais referido e portadores de enfisema apresentaram a maior proporção de mais de um tipo de tratamento utilizado. Entre os indivíduos que declararam ter apenas bronquite crônica, 55,1% (IC95% 48,7–61,4) usavam medicamento, 4,7% (IC95% 2,6–8,3) realizavam fisioterapia e 6,0% (IC95% 3,6–9,9) oxigenoterapia. Por outro lado, entre os enfisematosos, 44,1% (IC95% 36,8–51,7) realizavam tratamento medicamentoso, 8,8% (IC95% 5,4–14,2) fisioterapia e 10,0% (IC95% 6,3–15,6) oxigenoterapia. CONCLUSÕES: As prevalências de tratamentos para o manejo da DPOC estavam aquém do ideal em 2013. O medicamentoso foi o principal tipo de tratamento, seguido de oxigenoterapia e fisioterapia.
Hipertensão arterial e fatores associados: Pesquisa Nacional de Saúde, 2019
Authors: Malta Deborah Carvalho , Bernal Regina Tomie Ivata , Ribeiro Edmar Geraldo , Moreira Alexandra Dias , Felisbino-Mendes Mariana Santos , Velásquez-Meléndez Jorge Gustavo
Published: December 2022

OBJETIVO: Analisar os fatores associados à hipertensão arterial autorreferida, bem como sua prevalência, na população de adultos brasileiros. MÉTODOS: Foram analisados dados de 88.531 indivíduos de 18 anos ou mais que responderam à Pesquisa Nacional de Saúde de 2019. O desfecho estudado foi a hipertensão arterial autorreferida. Como exposições, foram consideradas variáveis sociodemográficas, condições clínicas e de estilo de vida. Para verificar os fatores associados à prevalência, usou-se como medida de associação a razão de prevalência (RP) bruta e ajustada por sexo, idade e escolaridade, obtidas por meio da Regressão de Poisson com variância robusta. RESULTADOS: A prevalência da hipertensão arterial autorreferida foi de 23,9% (IC95% 23,4–24,4). Ao ajustar por idade, sexo e escolaridade, as Razões de Prevalência ajustadas (RPaj) foram mais elevadas entre: auto avaliação de saúde regular (RPaj = 1,6; IC95% 1,5–1,6) e ruim (RPaj = 1,7; IC95% 1,6–1,8); autorreferência a doença do coração (RPaj = 1,7; IC95% 1,6–1,7), diabetes (RPaj = 1,7; IC95% 1,6–1,8), colesterol elevado (RPaj = 1,6; IC95% 1,6–1,7), sobrepeso (RPaj = 1,4; IC95% 1,4–1,5) e obesidade (RPaj = 2,0; IC95% 1,9–2,1); consumo elevado de sal (RPaj = 1,1; IC95% 1,0–1,1); entre ex-fumantes (RPaj = 1,1; IC95% 1,1–1,2) e menor entre fumantes (RPaj = 0,9; IC95% 0,8–0,9) e consumo de alimentos ultraprocessados (RPaj = 0,9; IC95% 0,8–0,9). CONCLUSÃO: Um quarto da população adulta brasileira afirma ter hipertensão arterial, de forma mais prevalente entre as mulheres e associada às maiores faixas etárias, cor da pele/raça preta, parda e outras, baixa escolaridade, consumo elevado de sal, ex-tabagismo, presença de comorbidades e pior autoavaliação de saúde.
A systematic review on the feeding ecology of Sloth Bear Melursus ursinus Shaw, 1791 in its distribution range in the Indian subcontinent
Authors: Rabari Vasantkumar , Dharaiya Nishith
Published: December 2022

The Sloth Bear being myrmecophagous is specialized to feed on ants, termites, and fleshy food; however, no discernible comparison exists on a diet, seasonal feeding pattern, and factor influence in a different habitat of an Indian sub-continent. A review of available literature suggested the dominance of plant matter in the Sloth Bear diet during the summer season, while an equal quantum of plant & animal matter was recorded in the monsoon & winter seasons. Fleshy fruits, flowers, flower buds, delicate leaves, and sometimes roots are considered plant food items in different studies, while ants, termites, honey, honey wax, and carrion feed are recorded as animal food items. Availability and accessibility of food materials in the different seasons, energy requirements, geographical variations, and human interference are notable factors influencing the feeding strategy of Sloth Bears. Cumulative data on food & feeding behavior of Sloth Bears helps to understand the pivotal role of species across various habitats. A systematic review of all the available studies to understand the diet of Sloth Bears in different seasons across its distribution range is presented in this paper, which can be a holistic approach to know the habitat selection with reference to the availability of food. A better understanding of such behavior also provides a key strategy for the management of large mammals in different geographical areas.
HOW SATISFIED ARE THE WHITE-COLLAR TURKS WORKING IN TALLINN: A QUALITATIVE RESEARCH
Authors: KOÇAK Alkım
Published: December 2022

The aim of this paper is to investigate job satisfaction of Turkish white-collar employees and to determine how multicultural companies in Tallinn satisfy their employees in the context of the Two-Factor Theory of Herzberg and location. To attain this purpose, we explore the job satisfaction of Turkish white-collar employees living in Tallinn. We used a semi-structured framework with in-depth interviews that included open and closed-ended questions based on a review of the literature. Snowball sampling was used in the selection of the interviewees and the sample was selected according to the job titles suitable for the definition of white-collar employee. Ten interviews with Turkish white-collar employees from six different multicultural firms were conducted. Our findings indicate that salary and supervision were shown to be crucial in enhancing Turkish white-collar employees' job satisfaction, according to the findings, based on Herzberg's Two-Factor Theory. White-collar employees expect good guidance and effective supervision from their managers, and a good salary has been shown to increase their job satisfaction.
FOOD WASTE BEHAVIOR OF ORGANIC FOOD CONSUMERS IN TURKEY
Authors: HAMZAOĞLU Nazife Merve , ÖZTÜRK GÖKTUNA Bilge
Published: December 2022

The amount of food lost or wasted is increasing in the world. While the problem of food waste is alarming, the existence of people suffering from hunger reveals the problem of the efficient allocation of food. Not only food waste is an economic problem, it is also an environmental problem. Thus, reducing food waste behaviour will be crucial in promoting sustainability and fighting against climate change. A widespread sustainable agricultural food production method is organic agriculture. The organic food demand is globally increasing with one of the main motivation, environmental concern. Organic consumers motivated to contribute to the environment and sustainability are also part of sustainable consumption. In this study, we reveal the food waste behaviour of organic food consumers. We have conducted an econometric analysis using data from 250 organic food consumers in five main districts of Istanbul. Our findings indicate that the frequency of organic food consumption negatively correlates with food waste. We see a general trend of low food waste among organic consumers, whereas their food waste behaviour varies regarding their organic food consumption frequency and product types.
Are all islands the same? A comparative thermoregulatory approach in four insular populations
Authors: Karameta Emmanouela , Sfenthourakis Spyros , Pafilis Panayiotis
Published: December 2022

As ectotherms, lizards, among the best models in thermal studies, are influenced by many abiotic factors. Interestingly, there is a scarcity of data regarding the impact that insularity may have on thermoregulation. Islands, depending their size and altitude, may differ considerably in the thermal conditions they provide to lizards. Here, we focused on a study system comprising islands that differ in morphological characteristics. We worked with four Rock Agama (Laudakia sp.) insular populations, namely Cyprus, Naxos, Delos, and Corfu. We measured body, operative and preferred temperatures and evaluated thermoregulation effectiveness (E). According to our findings, E differed among populations: Corfu received the lowest E (0.45), Cyprus and Naxos achieved median values (0.66 and 0.67, respectively) and lizards from Delos had the most effective thermoregulation (0.85). Our results underline the complex nature of insularity and its effect on saurian thermoregulation and highlight the importance of studying each insular population separately, taking into account the variable features of islands.
K.H. Miskotte and the Dutch Reformed Churches during the Occupation of The Netherlands
Authors: den Hertog Niels
Published: December 2022

This article is about the Dutch theologian K.H. Miskotte and his theologically based resistance against the Nazi occupation regime (1940–1945). The leadership in Dutch churches chose a cautious and often unprincipled approach to dealing with the occupier. Miskotte, along with some others, pointed to a different way. He wanted a better resistance, founded in the Bible. He read the Bible as the testimony of the Liberator-God who frees his people from slavery to the gods and powers of this world that blind and enslave people. Miskotte’s book Biblical ABC s, though created under the challenging circumstances of occupation by a Nazi regime, also points the way for today to a way of reading the Bible that is current and surprising.
The Name as ‘Anti-pagan’ Monument
Authors: Elbers Mirjam
Published: December 2022

K.H. Miskotte’s Bijbels ABC, recently translated into English as Biblical ABC s, resources resistance by carefully reading the Hebrew scriptures. This article argues that the central, defining theme of the book is the focus on the Name YHWH as ‘anti-pagan monument par excellence.’ Paganism for Miskotte does not mean the absence of religion nor a particular, polytheistic religion or worldview, but the natural human inclination to declare the existing order sacred. Humanity is profoundly ‘occupied’ and needs the Word, the Name-in-action, in order to be liberated from pagan, religious occupying forces—whether these forces are political, spiritual, military, economical or linguistic. This focus on the ‘anti-pagan’ stance of the Name determines the entire structure of Biblical ABC s, its method and content.
What are the Opinion Editorials Saying to the Church in the Philippines? Toward a Diagnostic Public Theology
Authors: Asiones Noel G.
Published: December 2022

This article seeks to contribute to the discourse from the perspective of opinion editorials (op-eds). We searched and collected a large sample of op-eds (N=110) from three major national newspaper archives to achieve this purpose. A thematic content analysis captured the central theme of the data related to the research question. There is a pressing need for the leaders of the Church to reform in three specific areas of its institution that can enable them to generate actions suitable to the changing social conditions. The results of this study have application potential for identifying the factors that could influence the reception or non-reception of the Church’s social and moral teachings in Philippine society with all its dynamic problems and challenges.