bluuebunny/crossref_metadata_2025 huggingface dataset:
On real and imaginary spaces: Mapping the archive
Authors: Nimmerfall Karina
Published: June 2018

The radically expanded concept of space, the so-called spatial turn found in the cultural and social sciences since the late 1980s, opens new possibilities for artistic practices that respond to the multilayered spaces of cities: the physical space with its built structures; the archive with its collected and catalogued documents as well as their systems of representation; and the imaginary space of certain cultural and ideological visions. Based on theories that assume these spaces not only determine each other and are mutually dependent, but overlap, and together create the space we experience, the article brings together two projects that map and explore urban settlements in London and Los Angeles by setting out a trail from the database of the archive: the historical records of the interdisciplinary British social research project Mass Observation (on London’s housing situation in the early 1940s) and collected data found on the social housing debate in Los Angeles during the early 1950s.
WORKSHOP REVIEW
Authors: Daly Deirdre
Published: June 2018

Picture This! Using the ‘Writing Essays by Pictures’ Approach to Teaching Academic Practice, 5 May 2017

A report on the workshop led by Alke Gröppel-Wegener, part of the Creative Teaching double bill organized by Andrew Walsh, at the St. Thomas Centre, Manchester
Educar ou instruir? Narrativas anarcossindicalistas nos primeiros anos da República Portuguesa: Revista Lumen (Lisboa, 1911-1913)
Authors: Barreira Luiz Carlos
Published: June 2018

Este artigo focaliza as ações de um grupo de intelectuais portugueses no início do século XX que se apresentava como anarcossindicalista. Autodenominado Grupo Lumen, suas ações visavam à formação do ser social. Dentre tais ações, o texto destaca a criação de uma revista, intitulada Lumen, por meio da qual o Grupo publicou suas teses sobre o educar e o instruir, tendo como referência as experiências da Escola Oficina Nº 1 de Lisboa e da Escola Moderna de Ferrer y Guardia, em Barcelona. A perspectiva de análise adotada pelo autor situa a imprensa no terreno da história social, no âmbito do qual ela é concebida como um conjunto de práticas constitutivas do social. Por meio da imprensa, o Grupo Lumen propôs um programa de instrução laica, científica e livre como condição necessária à criação de uma sociedade ácrata.Palavras-chave: Anarcossindicalismo, Formação libertária, Revista Lumen. Portugal. AbstractThis article focuses on the actions of a group of Portuguese intellectuals in the early twentieth century who presented itself as anarcho-syndicalist. Calling itself Lumen Group, its actions aimed at the formation of the human being. Among such actions, the text highlights the creation of a magazine, entitled Lumen, through which the Group published its thesis on educating and instructing, choosing as a reference the experiences of the Escola Oficina Nº 1 of Lisbon and the Escola Moderna, directed by Ferrer y Guardia, in Barcelona. The analytical perspective adopted by the author puts the press in the field of social history, under which it is conceived as a set of constitutive social practices. Through the press, the Lumen Group proposed a secular, scientific and free education program as a necessary component to create a self-governed (stateless) society.Keywords: Anarcho-syndicalism, Libertarian formation, Lumen Magazine. Portugal.ResumenEste artículo se centra en las acciones de un grupo de intelectuales portugueses a principios del siglo XX que se presentaba como anarcosindicalista. Autodenominado Grupo Lumen, sus acciones apunta a la formación del ser social. Entre estas acciones, el texto destaca la creación de una revista, titulada Lumen, por medio de la cual el Grupo publicó sus tesis sobre el educar y el instruir, eligiendo como referencia las experiencias de la Escuela Oficina Nº 1 de Lisboa y de la Escuela Moderna de Ferrer y Guardia, en Barcelona. La perspectiva de análisis adoptada por el autor sitúa a la prensa en el terreno de la historia social, en el marco del cual ella es concebida como un conjunto de prácticas constitutivas de lo social. A través de la prensa, el Grupo Lumen propuso un programa de instrucción laica, científica y libre como condición necesaria a la construcción de una sociedad ácrata.Palabras clave: Anarcosindicalismo; Formación libertaria, Revista Lumen. Portugal.
A cidadania na Revista Brasileira de Estudos Pedagógicos: publicações entre 1995 e 2013
Authors: De Oliveira Maria Augusta Martiarena , Corsetti Berenice
Published: June 2018

O tema da cidadania é constantemente utilizado em políticas educacionais e documentos institucionais. O presente trabalho insere-se em uma pesquisa maior, a qual analisa textos publicados na Revista Brasileira de Estudos Pedagógicos entre 1944 e 2013. Este estudo dedica-se especificamente ao período compreendido entre 1995 e 2013, fase em que houve maior número de publicações sobre o tema. Objetiva-se compreender a trajetória histórica do conceito de cidadania presente nas publicações da referida revista. Verificou-se que, a partir de 1995, houve aumento substancial no número de publicações sobre o tema. Tais publicações foram marcadas, também, pela variedade de concepções sobre cidadania e sua relação com diferentes áreas do conhecimento.Palavras-chave: Cidadania. Revista Brasileira de Estudos Pedagógicos. Impressos.Abstract The issue of citizenship is constantly used in educational and institutional policy documents. This paper is a part of a larger study, which analyzes texts published in the Journal of Pedagogical Studies between 1944 and 2013. This study is dedicated specifically to the period between 1995 and 2013, phase in which there was a higher number of publications about the theme. The objective is understanding the historical background of the concept of citizenship present in the magazine publications. We realize, since 1995, there was a substantial increase in the number of publications on the subject. These publications were also marked by the variety of conceptions about citizenship and its relationship with different areas of knowledge.Key words: Citizenship. Brazilian Magazine of Pedagogical Studies. Press.ResumenEl tema de la ciudadanía es frecuentemente utilizado em políticas educativas y documentos institucionales. Este trabajo es parte de una investigación más ampla, que se propone a analisar textos publicados en la Revista Brasileña de Estudios Pedagógicos entre 1944 y 2013. Este estudio se dedica especificamente al período entre 1995 y 2013, momento que más contó com publicaciones sobre el tema. Tenemos por objetivos comprehender la trayectoria histórica del concepto de ciudadanía presente em las publicaciones del referido periódico. Se constató que, a partir de 1995, el número de publicaciones sobre el tema cresció substancialmente. Además, las publicaciones fueron caracterizadas por la variedad de concepciones sobre ciudadanía y su relación com distintas areas del conocimiento.Palabras-clave: La ciudadanía. Revista Brasileña de Estudios pedagógicos. Impresa.
Concurrent Validity of a Rugby-Specific Yo-Yo Intermittent Recovery Test (Level 1) for Assessing Match-Related Running Performance
Authors: Dobbin Nick , Highton Jamie , Moss Samantha L. , Hunwicks Richard , Twist Craig
Published: June 2018

Dobbin, N, Highton, J, Moss, SL, Hunwicks, R, and Twist, C. Concurrent validity of a rugby-specific Yo-Yo intermittent recovery test (level 1) for assessing match-related running performance. J Strength Cond Res 35(1): 176–182, 2021—This study investigated the concurrent validity of a rugby-specific high-intensity intermittent running test against the internal, external, and perceptual responses to simulated match play. Thirty-six rugby league players (age 18.5 ± 1.8 years; stature 181.4 ± 7.6 cm; body mass 83.5 ± 9.8 kg) completed the prone Yo-Yo Intermittent Recovery Test (Yo-Yo IR1), of which 16 also completed the Yo-Yo IR1, and 2 × ∼20 minute bouts of a simulated match play (rugby league match simulation protocol for interchange players [RLMSP-i]). Most likely reductions in relative total, low-speed and high-speed distance, mean speed, and time above 20 W·kg−1 (high metabolic power [HMP]) were observed between bouts of the RLMSP-i. Likewise, rating of perceived exertion (RPE) and percentage of peak heart rate (%HRpeak) were very likely and likely higher during the second bout. Pearson's correlations revealed a large relationship for the change in relative distance (r = 0.57–0.61) between bouts with both Yo-Yo IR1 tests. The prone Yo-Yo IR1 was more strongly related to the RLMSP-i for change in repeated sprint speed (r = 0.78 cf. 0.56), mean speed (r = 0.64 cf. 0.36), HMP (r = 0.48 cf. 0.25), fatigue index (r = 0.71 cf. 0.63), %HRpeak (r = −0.56 cf. −0.35), RPEbout1 (r = −0.44 cf. −0.14), and RPEbout2 (r = −0.68 cf. −0.41) than the Yo-Yo IR1, but not for blood lactate concentration (r = −0.20 to −0.28 cf. −0.35 to −0.49). The relationships between prone Yo-Yo IR1 distance and measures of load during the RLMSP-i suggest that it possesses concurrent validity and is more strongly associated with measures of training or match load than the Yo-Yo IR1 using rugby league players.
Ethanol Regulates Presynaptic Activity and Sedation through Presynaptic Unc13 Proteins inDrosophila
Authors: Xu Shiyu , Pany Satyabrata , Benny Kevin , Tarique Khadeeja , al-Hatem Ola , Gajewski Kathleen , Leasure J. Leigh , Das Joydip , Roman Gregg
Published: June 2018

Ethanol has robust effects on presynaptic activity in many neurons, however, it is not yet clear how this drug acts within this compartment to change neural activity, nor the significance of this change on behavior and physiologyin vivo. One possible presynaptic effector for ethanol is the Munc13-1 protein. Herein, we show that ethanol binding to the rat Munc13-1 C1 domain, at concentrations consistent with binge exposure, reduces diacylglycerol (DAG) binding. The inhibition of DAG binding is predicted to reduce the activity of Munc13-1 and presynaptic release. InDrosophila, we show that sedating concentrations of ethanol significantly reduce synaptic vesicle release in olfactory sensory neurons (OSNs), while having no significant impact on membrane depolarization and Ca2+influx into the presynaptic compartment. These data indicate that ethanol targets the active zone in reducing synaptic vesicle exocytosis.Drosophila, haploinsufficent for the Munc13-1 orthologDunc13, are more resistant to the effect of ethanol on presynaptic inhibition. Genetically reducing the activity ofDunc13through mutation or expression of RNAi transgenes also leads to a significant resistance to the sedative effects of ethanol. The neuronal expression ofMunc13-1in heterozygotes for aDunc13loss-of-function mutation can largely rescue the ethanol sedation resistance phenotype, indicating a conservation of function betweenMunc13-1andDunc13in ethanol sedation. Hence, reducingDunc13activity leads to naïve physiological and behavioral resistance to sedating concentrations of ethanol. We propose that reducingDunc13activity, genetically or pharmacologically by ethanol binding to the C1 domain of Munc13-1/Dunc13, promotes a homeostatic response that leads to ethanol tolerance.
Searching for Nelly Kaplan
Authors: Dupont Joan
Published: June 2018

Critic Joan Dupont went in search of filmmaker Nelly Kaplan, whom she had met at an awards ceremony in Paris over a decade ago. She was famous for one film, La Fiancée du Pirate (A Very Curious Girl, 1969), which had taken France and the international world of women's film festivals by storm. She had slipped out of sight; nobody seemed to know where she was or why. At the Cinémathèque Française, there was only a kind of embarrassment when her name was mentioned and no plan to show her films. This past year has seen a resurgence of interest in the work of Kaplan, and the restoration and rerelease of some of her work by Lobster Films. Dupont met with Kaplan at her Paris apartment to discuss past, present, and future.
La Llamada, Paquita Salas, and the Javis
Authors: Smith Paul Julian
Published: June 2018

FQ Columnist Paul Julian Smith reviews the recent work of young writer-directors Javier Ambrossi and Javier Calvo, celebrities universally known in Spain by the diminutive of their shared name, “los Javis.” The backstory to their first feature film, the success of which so mystifies the established film press, is that of the couple's canny and creative appeal to the multiple media of theater, television, and Internet. The Javis work marks the emergence of a new youthful sensibility and a new gay auteurism in Spanish film and television.
The War for Nostalgia: Sanjay Leela Bhansali's Padmaavat
Authors: Qureshi Bilal
Published: June 2018

In November 2017, on the eve of his career's biggest release, Bollywood filmmaker Sanjay Leela Bhansali was in hiding under police protection. His magnum opus Padmaavat, originally scheduled to be released across the world on December 1, was postponed indefinitely. The film's lead actress, Deepika Padukone, had a bounty placed on her head. Posters of the film were already burning across India as the country's censor board dissected the film for inflaming “cultural sensitivities.” The furor centered on Bhansali's portrayal of a mythical fourteenth-century Hindu queen named Padmavati, lionized for burning herself alive in the face of a Muslim invasion. Karni Sena, a right-wing Hindu nationalist group, claimed that the (unseen) film showed their revered queen dancing and romancing the film's Muslim villain. The allegation was enough to spark calls for the film to be banned. Violent protesters, political opportunists, and cable news personalities followed suit. Could the increasingly violent threats from Hindu nationalists succeed in silencing Bhansali's life's work? Qureshi discusses how once the film was released and the Karni Sena withdrew its protests about the film, his own struggles with it began.
What It Means to Be High Maintenance
Authors: Benson-Allott Caetlin
Published: June 2018

Character-centered storytelling helped High Maintenance take off as a web series and become one of the most celebrated shows currently airing on HBO. But the series’ success across both platforms raises the question: what is the difference between a web series and a television series? Between 2012 and 2015, the High Maintenance web series adopted an innovative approach to serial storytelling by privileging contiguity over continuity, accumulation over connection. The web series comprises nineteen short episodes, each a single vignette allowing a brief glimpse into the life of one protagonist or social group. The series facilitated an additive model of episodic narration that fit its narrative premise and its vision of Brooklyn, even though it never quite realized the diversity its model allowed for.
Progressive methylation of POU5F1 regulatory regions during blastocyst development
Authors: Canon E , Jouneau L , Blachère T , Peynot N , Daniel N , Boulanger L , Maulny L , Archilla C , Voisin S , Jouneau A , Godet M , Duranthon V
Published: June 2018

ThePOU5F1gene encodes one of the ‘core’ transcription factors necessary to establish and maintain pluripotency in mammals. Its function depends on its precise level of expression, so its transcription has to be tightly regulated. To date, few conserved functional elements have been identified in its 5′ regulatory region: a distal and a proximal enhancer, and a minimal promoter, epigenetic modifications of which interfere withPOU5F1expression and function inin vitro-derived cell lines. Also, its permanent inactivation in differentiated cells depends onde novomethylation of its promoter. However, little is known about the epigenetic regulation ofPOU5F1expression in the embryo itself. We used the rabbit blastocyst as a model to analyze the methylation dynamics of thePOU5F15′ upstream region, relative to its regulated expression in different compartments of the blastocyst over a 2-day period of development. We evidenced progressive methylation of the 5′ regulatory region and the first exon accompanying differentiation and the gradual repression ofPOU5F1. Methylation started in the early trophectoderm before complete transcriptional inactivation. Interestingly, the distal enhancer, which is known to be active in naïve pluripotent cells only, retained a very low level of methylation in primed pluripotent epiblasts and remained less methylated in differentiated compartments than the proximal enhancer. This detailed study identified CpGs with the greatest variations in methylation, as well as groups of CpGs showing a highly correlated behavior, during differentiation. Moreover, our findings evidenced few CpGs with very specific behavior during this period of development.
Стан готовності майбутніх фахіців сфери Туризму до організації екскурсійної діяльності
Authors: Litovka-Demenina Svitlana
Published: June 2018

Стаття присвячена аналізу результатів експериментальної роботи етапу дослідження перевірки готовності майбутніх фахівців сфери туризму до екскурсійної діяльності. Визначено діагностичний інструментарій ефективності сформованості готовності майбутніх фахівців сфери туризму до екскурсійної діяльності в процесі професійної підготовки: критерії, показники та рівні. Означено методику формувального етапу через впровадження спецкурсу «Організація екскурсійної діяльності» в експериментальних групах.
Current Evidence on Dental Implants Outcomes in Smokers and Nonsmokers: A Systematic Review and Meta-Analysis
Authors: Alfadda Sara A.
Published: June 2018

This systematic review aims to answer the following PICO (Participants, Intervention, Comparison, and Outcome) question: “Does smoking increase the rates of implant failure and peri-implant marginal bone loss in patients with dental implants?” An extensive electronic search of the Cochrane Central Register of Controlled Trials, PubMed, Medline, Embase, and Web of Science databases and a subsequent hand search were performed. Only randomized controlled trial, controlled clinical trials, and prospective studies published up to January 2017 were included. For dichotomous outcomes, the effect estimates for smoking are expressed as odds ratios and 95% CIs. For continuous outcomes, weighted mean differences (WMDs) and 95% CIs are presented. Three randomized controlled trials and 7 prospective studies were included. The odds ratio for implant failure among smokers was 2.92 (95% CI, 1.76–4.83) (P < .001). First-year marginal bone loss in smokers ranged from 0.02 to 0.45 mm. In the nonsmokers, bone loss ranged from −0.08 to 0.42 mm. Nonsmokers lost significantly less bone during the first year (WMD = 0.11 mm, 95% CI. 0.03–0.19) and subsequent years (WMD = 0.11 mm, 95% CI, 0.03–0.19, P = .009). The available scientific evidence suggests that smoking is associated with significantly increased rates of implant failure and marginal bone loss.
Assessing Criterion Validity of Using Internet Searches as a Measure of Public Attention
Authors: Stiles Elizabeth A. , Grogan-Myers Patrick E.
Published: June 2018

We examine the criterion validity of using internet searches as a measure of public attention to United States Supreme Court (USSC) cases.  First, we construct a measure of public attention to three cases by comparing relevant search terms in Google Trends to one top search terms of the year, then sum the measure week by week during the period of the research design.  To test the measure’s criterion validity, we replicate Scott and Saunders’ (2006) models using their dataset (created by conducting phone interviews of a national sample using random digit dialing) that was designed to assess awareness of USSC decisions. We find that public attention as measured by Google Trends data is predictive of public awareness of USSC decisions for two of their three models. We conclude that using free, publically available big data to measure public attention to USSC cases has criterion validity, and is a valuable tool for researchers studying public policy and process.
El encuadre de las enfermedades raras en los medios de comunicación españoles
Authors: López-Villafranca Paloma , Castillo-Esparcia Antonio
Published: June 2018

El colectivo de pacientes con enfermedades raras en España ha destinado sus esfuerzos en los últimos cinco años en lograr mayor visibilidad en los medios de comunicación. Con patologías que afectan a menos de 5 por cada 10.000 habitantes, se enfrentan al reto de ocupar un lugar en la sociedad como colectivo para legitimar sus propuestas y sensibilizar a la opinión pública. En este artículo analizamos 527 piezas que se han publicado en prensa, (El País, El Mundo, ABC, La Vanguardia, El Periódico), que se han emitido en radio (SER, COPE, Onda Cero, RNE), y televisión (TVE, Telecinco, Antena 3, La Sexta, Cuatro), en el periodo de 2012 a 2014. Los resultados muestran que ha aumentado la visibilidad y el conocimiento sobre estas patologías y se refleja una imagen proactiva de este colectivo gracias a sus iniciativas y reivindicaciones.
To be or not to be the media industry – Delineation to a fuzzy concept
Authors: Komorowski Marlen , Ranaivoson Heritiana Renaud
Published: June 2018

Even though media industry studies are on the rise, there is a major issue: the concept itself is “fuzzy”. The goal of this paper is to shed light on the concept. To do so, the paper analyses existing approaches, combining academic references as well as sources commonly used by practitioners (e.g. the OECD, the EU, DCMS). It allows to give three delineations to the media industry: (1) A novel theoretical delineation, (2) a sectoral delineation, and (3) a delineation through the NACE statistical classification system. The main research findings are: (i) the development of a so-called circling model that shows how “mediated content” is at the core of the definition of the media industry; (ii) through the convergence tendencies, many different media activities can play a supporting or facilitating role; (iii) a list of NACE codes to guide statistical analysies.
Benfica vs Sporting: o derby visto a partir do Twitter
Authors: Gouveia Célia , Lapa Tiago , Di Fátima Branco
Published: June 2018

O presente artigo tem como objetivo encontrar e analisar um determinado conjunto de perfis, o tipo de vínculos sociais que estabelecem, assim como a importância e influência dos seus papéis no Twitter durante o derby de Lisboa entre o Sport Lisboa e Benfica e o Sporting Clube de Portugal, realizado no dia 11 de dezembro de 2016. Apresentamos como estratégia de pesquisa um estudo de caso baseado no fluxo de mensagens publicadas na rede social indexadas com as hashtags #benfica e #sporting no dia e hora do derby. Foram interpretados através da Análise de Redes Sociais (SNA) uma amostra de 39.540 tweets e retweets postados por 18.710 perfis, provenientes da análise exploratória da rede de relações mediadas entre utilizadores da Twittersphere. Com base na observação da importância das relações entre unidades de interação, derivamos para o modelo de Análise e Visualização de Rede (NAV) e identificámos, através de grafos representativos dos dados obtidos, pistas que julgamos pertinentes para o entendimento de uma audiência moldada pela lógica da produção e circulação de mensagens afetas a uma determinada cultura de fãs cada vez mais em rede.
Presencia de factores motivacionales extrínsecos para el emprendimiento en los gobiernos electrónicos de los países de la comunidad andina
Authors: Vivas-García Marisela , Cuberos Maria Antonia , Albornoz-Arias Neida , Mazuera-Arias Rina , Carreño-Paredes Myriam Teresa
Published: June 2018

El estudio tiene como finalidad detectar la presencia de factores motivacionales extrínsecos para el emprendimiento, desde las capacidades comunicacionales en los portales de Gobiernos Electrónicos (GE) de los países que conforman la comunidad Andina (CAN) para el apoyo al ciudadano que busca emprender. Para ello se utilizó una metodología evolutiva/ incremental, que revela la secuencialidad procesual que subyace en las primeras fases de un emprendimiento, mediante un conjunto de variables implícitas en cada una de las dimensiones/fases seleccionadas apriorísticamente que dan cuenta de: a) presencia de factores motivacionales, b) información relativa a los mismos y c) comunicación Gobierno- ciudadano. Los resultados indican la alta presencia de factores motivacionales y de información sobre los mismos en los sitios Web gubernamentales de la CAN. Sin embargo, la secuencialidad del proceso se ve alterada en la dimensión comunicación del ciudadano con los entes gubernamentales, debido a la baja presencia de servicios en línea y herramientas activas que faciliten el proceso comunicacional en tiempo real. Se concluye que los GE de los países de la CAN entendidos como concepto integral coadyuvan en el empoderamiento de la ciudadanía y pueden llegar a tener incidencia relacional con la población mediante la mejora de su cultura emprendedora.
CheckMate 141: 1-Year Update and Subgroup Analysis of Nivolumab as First-Line Therapy in Patients with Recurrent/Metastatic Head and Neck Cancer
Authors: Gillison Maura L. , Blumenschein George , Fayette Jerome , Guigay Joel , Colevas A. Dimitrios , Licitra Lisa , Harrington Kevin J. , Kasper Stefan , Vokes Everett E. , Even Caroline , Worden Francis , Saba Nabil F. , Iglesias Docampo Lara Carmen , Haddad Robert , Rordorf Tamara , Kiyota Naomi , Tahara Makoto , Monga Manish , Lynch Mark , Li Li , Ferris Robert L.
Published: June 2018

Nivolumab significantly improved overall survival (OS) vs investigator's choice (IC) of chemotherapy at the primary analysis of randomized, open-label, phase 3 CheckMate 141 in patients with recurrent or metastatic (R/M) squamous cell carcinoma of the head and neck (SCCHN). Here, we report that OS benefit with nivolumab was maintained at a minimum follow-up of 11.4 months. Further, OS benefit with nivolumab vs IC was also noted among patients who received first-line treatment for R/M SCCHN after progressing on platinum therapy for locally advanced disease in the adjuvant or primary (i.e., with radiation) setting.
Epithelial and Endothelial Pannexin1 Channels Mediate AKI
Authors: Jankowski Jakub , Perry Heather M. , Medina Christopher B. , Huang Liping , Yao Junlan , Bajwa Amandeep , Lorenz Ulrike M. , Rosin Diane L. , Ravichandran Kodi S. , Isakson Brant E. , Okusa Mark D.
Published: June 2018

Background Pannexin1 (Panx1), an ATP release channel, is present in most mammalian tissues, but the role of Panx1 in health and disease is not fully understood. Panx1 may serve to modulate AKI; ATP is a precursor to adenosine and may function to block inflammation, or ATP may act as a danger-associated molecular pattern and initiate inflammation.

Methods We used pharmacologic and genetic approaches to evaluate the effect of Panx1 on kidney ischemia-reperfusion injury (IRI), a mouse model of AKI.

Results Pharmacologic inhibition of gap junctions, including Panx1, by administration of carbenoxolone protected mice from IRI. Furthermore, global deletion of Panx1 preserved kidney function and morphology and diminished the expression of proinflammatory molecules after IRI. Analysis of bone marrow chimeric mice revealed that Panx1 expressed on parenchymal cells is necessary for ischemic injury, and both proximal tubule and vascular endothelial Panx1 tissue-specific knockout mice were protected from IRI. In vitro, Panx1-deficient proximal tubule cells released less and retained more ATP under hypoxic stress.

Conclusions Panx1 is involved in regulating ATP release from hypoxic cells, and reducing this ATP release may protect kidneys from AKI.
Prevalence of caries and gingivitis in 2- to 4-year-old children attending daycare centers managed by the Chilean National Kindergartens Board (JUNJI) and municipal schools, Valdivia
Authors:   Universidad Austral, Valdivia, Chile., Soto Yarela , Wilson Camila ,   Universidad Austral, Valdivia, Chile., Herreros Carmen ,   Department of Odonto-Stomatology, Universidad Austral, Valdivia, Chile.
Published: June 2018

Objective: To determine the prevalence of carious lesions and gingivitis in 2- to 4-year-old children attending JUNJI daycare centers and urban municipal schools in the city of Valdivia, Chile. Material and method: Descriptive cross-sectional study. A population of 182 two-year-old children and 285 four-year-old children were examined. Subjects were selected by stratified random sampling. All subjects were enrolled in daycare centers managed by JUNJI and municipal schools in the city of Valdivia. An oral examination was performed to measure the DMFT and hemorrhagic indexes according to the WHO diagnostic criteria. The presence of cavitated carious lesions and gingivitis was determined, resulting in descriptive statistics according to age and gender. Results: The prevalence of caries was 12.6% in two-year-old children and 41% in four-year-olds, respectively. The prevalence of gingivitis was 36.8% at 2 years of age and 70.5% at 4 years. There were no significant differences by gender at 2 years of age (p=1) or at 4 years (p=0.37). Two year-old children have significantly fewer carious lesions and gingivitis less frequently than four-year-olds (p=<.001). Conclusion: Two year-old children have a lower prevalence of carious lesions and gingivitis than four-year-old ones. No relationship between the variables and gender was found.
Bullying in schoolchildren according to Angle’s classifications of malocclusion
Authors:   Private Practice, Peru., Quito-Rabanal Ximena , Carruitero Marcos J. ,   Stomatology School Antenor Orrego Private University. Trujillo, Peru.
Published: June 2018

Objective: To compare bullying in schoolchildren according diffe-rent types of Angle’s malocclusion. Materials and methods: A cross-sectional and prospective study was performed. 217 schoolchildren were evaluated. A scale-adapted validated questionnaire was applied to measure general bullying. Malocclusion was classified according to Angle’s classification. Comparison in bullying between different types of malocclusions was performed by Kruskal Wallis non-parametric test. Multiple linear regression analysis was also performed. Results: No statistically significant differences in bullying between the different types of Angle’s malocclusion was found (p=0.295). Multiple linear regression applied to bullying scores treated as dependent variable with malocclusion, sex, and age showed no influence of these variables on bullying (R2=0.0027, p>0.05). Conclusion: Bullying in schoolchildren does not differ according Angle’s classification of malocclusion. Further studies are necessary to emphasize the assessment of bullying related to malocclusion of anterior teeth.
ON ŞAİRİN BİRLİKTE MEŞKİ: “LÂLE-RUH” ÜZERİNE YAZILMIŞ ON NAZİRE
Authors: Yılmaz Kadri
Published: June 2018

Bir şeye benzemek için yapılan iş, örnek,
karşılık gibi anlamlara gelen nazire, terim olarak bir şairin başka bir şairin
şiirini model alıp aynı vezin, kafiye veya da redifte yeni bir şiir ortaya
koymasıdır. Çeşitli konuları içeren mecmuaların yanında sadece nazirelerin
derlendiği mecmualar da mevcuttur. İsimleri ve şiirleri gün yüzüne çıkmamış
şairler için ilk elden kaynaklar olan mecmuaların önemli işlevlerinden birisi
de şairlerin çeşitli nedenlerle divan metnine girmemiş şiirlerini
barındırmasıdır. Bu çalışmada, Michigan Üniversitesi Türkçe Yazmaları
koleksiyonu 356 numarada kayıtlı bir mecmuada yer alan Gıyâsî, Yümnî, Nâlişî,
Sâ’î, Husrev, Bedrî, Fürûgî, Edâyî, Muhtârî ve Azîzî’ye ait on nazire
incelenmiştir. Araştırmacıların bir
şiirin nazire olup olmadığıyla ilgili olarak belirledikleri kıstaslar olan
“vezin, kafiye ve muhteva ortaklığı” bakımından tüm şiirlerin uygunluğu söz
konusudur. Şiirler muhteva bakımından şekil ve muhteva bakımından incelenmiş;
“sevgilinin boyu, yüzü, dudağı ve âşıkla olan münasebeti” başlıkları altında
şairlerin çizdiği ortak hayaller tespit edilmeye çalışılmıştır.
YABANCI DİL OLARAK TÜRKÇE ÖĞRETİMİNİN KÜLTÜREL BOYUTU: TÜRKÇE KALIP SÖZLERİN FARSLARA ÖĞRETİMİ
Authors: Boylu Emrah , Başar UMUT
Published: June 2018

Türkçenin yabancı dil olarak öğretimi
literatürüne bakıldığında, Türkçenin sözvarlığı içerisinde önemli bir yere
sahip olan kalıp sözlerin öğretimine yeterince değinilmediği dikkati
çekmektedir.  Ancak kalıp sözler
kullanıldıkları toplumun dil ve kültür yapısını yansıttığı için yabancı dil
öğretiminde, hem hedef kitle hem de dil öğretenler açısından son derece
önemlidir. Bu önem, yabancı dil öğretiminde iletişimsel yaklaşımların
yaygınlaşmasıyla birlikte daha da belirgin bir şekilde ortaya çıkmıştır. Bu
bilgiler ışığında bu çalışmada, Türkçe ile Farsça arasındaki sık kullanılan ve
eşdeğer olan 232 adet kalıp söz tespit edilmiş ve Türkçeyi yabancı dil olarak
öğrenen Farslara bu sözlerin öğretiminde (farkındalık kazandırılmasında), Türk
ve Fars kültürünün müşterek unsurlarından nasıl yararlanılacağı açıklanmıştır.
Bunlara ek olarak, yine Türkçede olup fakat Farsçada karşılığı olmayan ancak
Türkçede sık olarak kullanılan toplam 45 adet kalıp söz tespit edilerek özelde
Farslara Türkçe öğretiminde, genelde ise yabancılara Türkçe kalıp sözlerin
öğretimi sürecinde dikkat edilmesi gereken temel hususların neler olduğu
açıklanmıştır.
Mutavassıtîn DevrindeTürkçe Fransızca Bir Edebiyat Dergisi Ma’rifet ve Edebiyatımıza Kazandırdıkları
Authors: Soydaş Hakan
Published: June 2018

Yenileşme devri edebiyatımızın ilk adımları öncelikle gazetelerde
görülür. Osmanlı coğrafyasındaki ilk gazeteler yabancı dilde özellikle
Fransızca olarak neşredilmişlerdir. Türkçe yayımlanan gazetelerle birlikte
edebiyatımız için yeni bir dikkat gelişmeye başlar. Batı edebiyatına özgü edebî
türlere dair ilk denemeler bu gazetelerde tebarüz eder. Edebî dergilerin
yaygınlık kazanmasıyla birlikte çok sayıda eserin tercüme edildiği görülür.
Fransız edebiyatı beslenilen kaynakların başında gelir. Edebiyatta asrîleşmek
yabancı dil bilmeyi ve Batılı edebiyatlardan yararlanmayı gerektirir.Ma’rifet dergisi gerek muhtevî olduğu eserler ve tercümeler
gerekse de yayın politikası açısından devri içinde öne çıkar. Rum asıllı
Théodossia’nın gayretleri ile yayımlanmaya başlanan dergi Türkçe ve Fransızca
nüshalar halinde yayımlanır. Derginin sahibesi bunun nedeninin genç Osmanlılara
Fransızcayı öğretmek olduğunu izah eder. Dergideki tercüme eserler asılları ile
birlikte verilir. Dergide aynı zamanda sanat ve bilime dair makaleler de
mevcuttur.

   Bu çalışmanının
amacı Mutavassıtîn devrinde yayımlanan Ma’rifet dergisini çıkardığımız fihrist
eşliğinde incelemektir. Klasik Türk edebiyatına mahsus edebî türlerin de
görüldüğü dergide Fransız yazar ve şairlerin eserlerine ve makalelerine tesadüf
edilir. Dergi bu özelliği ile Mutavassıtîn haiz olduğu dualiteyi ortaya koyması
açısından önemlidir.
TÜRK KÜLTÜRÜNDE MİTOLOJİK BİR KAHRAMAN OLARAK ÂŞIKLAR
Authors: Çapraz Erhan
Published: June 2018

Âşık tarzı şiir geleneği, Türkistan’da teşekküle
başlayan Türk sözel edebiyat geleneğinin en önemli yanıdır. Hiç şüphesiz
geleneğin bugünlere kadar ulaşmasında iletişim odaklarına bağlı “aktarıcı/anlatıcı/sanatkâr”
vasfına sahip âşıkların katkısı büyüktür. Ayrıca onlar, evren ve
yaratılışla ilgili algıların hatırlatılması bağlamında “kültürel belleğin uzman
taşıyıcıları” olarak da karşımıza çıkmaktadır. Dolayısıyla âşıklar bu süreçte
‘mitik’ diyebileceğimiz bir varoluş süreci de yaşamışlardır. Bu süreci olası
kılan şey ise ‘kompleks rüya motifi’dir. Şamanlığa kabul merasiminden itibaren
bu motif kodlayıcı bir karakter kazanarak âşıkların mitolojik bir kahramana
dönüşmesini sağlamıştır. Âşıkların eserlerinde karşımıza çıkan mitolojik tasavvur
ve tasvirler varoluş sürecinde bu dönüşümün tezahürleri olarak da
düşünülebilir. Ayrıca bazı âşıkların kültleşmeye doğru gitmeleri de doğrudan bu
varoluş süreciyle ilintili olabilir. Bu açıdan yazıda Joseph Campbell’ın
‘kahraman’ kavramsallaştırması temelinde bir değerlendirmeye girişilerek
âşıkların mitolojik bir kahraman olarak da ele alınabileceği hususu ortaya
konulacaktır.
NECMETTİN SADIK SADAK’TAN TÜRKLEŞMEK, İSLAMLAŞMAK, MUASIRLAŞMAK ve TÜRKÇÜLÜĞÜN ESASLARI HAKKINDA
Authors: Şahin Hafize
Published: June 2018

Cumhuriyet döneminin ilk kuşağında yer alan Necmettin
Sadık Sadak (1890-1953) gazeteci, sosyolog ve siyasetçi kimlikleriyle karşımıza
çıkar. Necmettin Sadık Sadak, İstanbul Üniversitesinde Ziya Gökalp’ın müderris
muavinliği görevini sürdürür. Ziya Gökalp’ın Malta’da sürgün olduğu dönemde de
halefi olarak aynı kürsünün başına geçer. Necmettin Sadık Sadak, Ziya Gökalp’ın
iki önemli eserini Yeni Mecmua’da tanıtır. Tanıttığı eserlerin ilki
1918’de yayımlanan Türkleşmek, İslamlaşmak, Muasırlaşmak; ikincisi ise 1923’te
yayımlanan Türkçülüğün Esasları’dır. Atatürkçü ideolojinin teorisyeni
Ziya Gökalp’ı takip eden Necmettin Sadık Sadak’ın bu tanıtmaları daha önce
hiçbir yerde günümüz alfabesiyle yayımlanmamıştır. Bu tanıtma yazıları Türk
kültür tarihinde önemli bir yere sahip iki eserin kendi döneminde nasıl
karşılandığını göstermesi bakımından önemlidir. Akademik araştırmalarda
faydalanılabilmesi için bu tanıtma yazıları eski harfli Türkçeden günümüz
alfabesine çevrilmiştir. Necmettin Sadık Sadak, Ziya Gökalp’ın kitaplarını
ayrıntılı olarak tetkik etmemiştir; ancak bu kitap tanıtımları Necmettin Sadık
Sadak’ın Ziya Gökalp’la ortak bakış açısını ve Türkçülüğü desteklediğini
yansıtması bakımlarından önemlidir. 1910’lardan 2017’ye değin Türkleşmek,
İslamlaşmak, Muasırlaşmak ve Türkçülüğün Esasları kitapları farklı
yayınevleri tarafından yayımlanmış ve her dönemde okurla buluşmuştur. Bu
çalışmada Necmettin Sadık Sadak’ın kitap tanıtımları eklerde verilerek Ziya
Gökalp’ın bu iki eseri üzerinde durulacak ve kitap tanıtımları
değerlendirilecektir.
Evaluation of locally available synthetic macro fibres in a single-fibre pullout test in concrete
Authors: Odendaal C M , Babafemi A J , Combrinck R , de Villiers W I , Boshoff W P
Published: June 2018

There is increasing use of synthetic macro fibres in concrete applications. However, the performance of these fibres varies, based on various factors. This study investigates the fibre/ matrix interface performance of four types of synthetic macro fibres locally available in the South African construction market. The influence of water-cement ratio (w/c), fibre embedment length, fibre properties and fibre snubbing angle on the single-fibre pull-out behaviour is studied in this paper. The influence of some of these properties on the compressive strength is also evaluated. Three mix designs and four fibre types were used for the investigation. All tests were performed in a controlled climate room. Specimens with single fibres were tested in a Universal Testing Machine. Scanning Electron Microscope (SEM) images of pulled out fibres were examined for inferences. The results have shown that w/c has no influence on the pull-out load of synthetic macro fibres. However, the pull-out load increases with increase in fibre embedment length and equivalent fibre diameter. Pull-out load increases for flat fibres bent along their strong axis as the fibre snubbing angle increases. While crimped fibres with improved geometry show optimum pull-out performance when pulled out perpendicularly to the crack plane, flat fibres performed better at the snubbing angles tested. SEM images also show more surface damage on fibres with irregular geometry.
The effect of aeration through an internal gallery of a dam on the cavitation risk of Roberts splitters
Authors: Calitz G , Basson G R
Published: June 2018

Roberts splitters is an effective means of energy dissipation for dam spillways. Roberts' (1943) standard unaerated splitter design procedure is, however, limited to a spillway head (H) of 3.0 m (q ~ 12 m2/s). In order to avoid cavitation at higher design spillway heads, this study investigated the artificial aeration of the flow by local air vents positioned on the splitters. A 1:20 scale hydraulic model of an ogee spillway equipped with Roberts splitters was constructed. Two aerated models, with differently sized air vents, were compared to an unaerated control model in order to determine the effect that the proposed aeration system has on the cavitation risk of the splitters at prototype unit discharges (q) of up to 50 m2/s. At the maximum tested spillway head of 7.6 m (q = 50 m2/s) the minimum pressures and air concentration around the splitters of both aerated models increased considerably. It was further observed that the unaerated splitters were prone to drowning at high spillway heads, leading to unfavourable hydraulic conditions. Based on the results of this study, the addition of aeration through an internal aeration gallery can increase the unit discharge capacity of Roberts splitters to at least 50 m2/s, up by 43%, from the unaerated limit of 35 m2/s.
Comparative analysis of methods of pile-bearing capacity evaluation using CPT logs from tropical soils
Authors: Obeta I N , Onyia M E , Obiekwe D A
Published: June 2018

This study presents the results of a comparative analysis of the performance of eight direct cone penetration test (CPT) methods in predicting the ultimate load-carrying capacity of a 300 mm diameter end-bearing pile, evaluated at defined soil depths using CPT logs obtained for various locations in the south-east and south-south regions of Nigeria. The methods used are the Schmertmann (1978), LCPC (Bustamante & Gianeselli 1982 - Laboratoire Central des Ponts et Chausees), De Ruiter and Beringen (1979), Tumay and Fakhroo (1982), Price and Wardle (1982), Philipponnat (1980), Aoki and De Alencar (1975), and the Penpile methods (Clisby et al 1978). The results of univariate analysis of variance indicated that the interactions between location and treatment (methods of pile capacity prediction), depth and treatment, and location and depth were statistically significant for cohesionless soils, but that the interaction between depth and treatment was not statistically significant for cohesive soils. Also, post-hoc tests (Least square difference and Bonferroni methods) showed that the LCPC and Philipponnat methods are best suited for cohesionless soils, while the LCPC, Tumay and Fakhroo (1982) and De Ruiter and Beringen (1979) methods are recommended for cohesive soils.
The effect of neoprene thumb abduction splints on upper limb function in children with cerebral palsy
Authors: Hughes Ashleigh , Franzsen Denise , Freeme Juliana
Published: June 2018

INTRODUCTION: Children with cerebral palsy (CP) have limitations in hand function due to weakness and spasticity, with long term effects causing shortening and stiffness of muscles in the hand and arm. The soft neoprene thumb abductor splint is prescribed by occupational therapists to correct these impairments. There is insufficient evidence for the effectiveness of this splint on upper limb function in children with CP with a thumb-in-palm deformity within the South African public health context. METHODS: A non-blinded randomised intervention study was carried out in a CP clinic at a tertiary level public hospital. Twenty-eight CP children between the age of 18 and 68 months, presenting with thumb-in-palm deformity, functioning on a Level II to IV on the Gross Motor Function Classification Scale (GMFCS) participated in the study. The Quality of Upper Extremity Skills Test (QUEST) was used to assess upper limb function in terms of dissociated movement, grasps, weight bearing and protective extension to obtain baseline information. Both the intervention and control groups received monthly individual occupational therapy and a home programme over a three month period. The intervention group additionally received a soft neoprene thumb abduction splint. RESULTS: No statistically significant differences between the intervention and control groups were found. Clinically relevant between group differences indicated by effect sizes were found however with large effect sizes the for the total QUEST score and weight bearing. The effect size for improvement within the intervention group was large for dissociated movement and weight bearing with and without the splint on as well as for grasps with the splint on. Only dissociated movement showed a clinically relevant medium effect size for change within the control group. Protective extension decreased within both groups except for the intervention group with the splint on. The caregivers/parents perceived the home programme as easy to follow, and those who were prescribed the splint mostly reported that it was easy to use. CONCLUSION: Soft neoprene thumb abduction splints have a positive effect on weight bearing and upper limb function in children with thumb-in-palm deformity, particularly with the splint on. Further research is recommended in the area of splinting in CP. Key words: Cerebral palsy, thumb-in-palm deformity, neoprene thumb abductor splint, QUEST
The effects of rehabilitation education for village health volunteers on walking speed and upper extremity function in stroke survivors in Thailand
Authors: Chinchai Pisak , Khamwong Peanchai
Published: June 2018

INTRODUCTION: Stroke can cause long-term disabilities to survivors. Rehabilitation is an on-going process and should, ideally, be provided to these people in their homes. This study aimed to investigate the effect that rehabilitation education provided to village health volunteers (VHVs) would have on walking speed and upper extremity (UE) function in stroke survivors who stay at home in Thailand. METHODS: Participants were recruited by purposive sampling, which included 27 stroke survivors from four municipalities in Chiang Mai and Lamphun provinces. The measuring instruments used were the Ten-Meter Walk Test and the UE motor domain of the Fugl-Meyer Assessment. Researchers presented a 7-hour rehabilitation education programme to VHVs, who then made weekly1-hour visits to the homes of stroke survivors to implement the rehabilitation programme over eight weeks. Data were collected within seven days before and again after the 8-week programme. RESULTS: Descriptive statistics and the paired t-test were applied to analyse the data. Results showed that the participants used significantly less walking time from pre-test ( X =34.73 ±8.48) to post-test ( X =32.18±9.32) (p<0.05). However, the score of UE function at pre-test (X=36.81±9.59) was not significantly different from that at post-test (X =37.26±9.67). CONCLUSION: The findings suggest that trained VHVs can be part of the rehabilitation team and contribute to improved functional performance for disabled stroke survivors, particularly in developing countries. Key words: Hand function, gait speed, Home visit, motor function after stroke, community rehabilitation, home-based rehabilitation
Valence-space associations in vertical touchscreen interactions v1
Authors: Cervera-Torres Sergio , Ruiz Fernández Susana , Lachmair Martin , Gerjets Peter
Published: June 2018

Embodied cognition research suggests that bodily experiences might ground mental representations of emotional valence in the vertical dimension of space (i.e., positive is up and negative is down). Accordingly, recent studies show that upward and downward arm movements may also influence the evaluation of valence-laden stimuli, suggesting that upward (downwards) movements lead to more positive (negative) evaluations. Interestingly, these studies typically did not investigate paradigms that require a direct hand interaction with the stimuli. With the advent of touchscreen devices and their use for experimental environments, however, a direct and more natural hand interaction with the stimuli has come to the fore. In this regard, the goal of the present study is to examine how direct hand interaction with valence-laden stimuli on a touchscreen monitor affects their perceived valence. To do so, participants evaluated emotional pictures after touching and moving them either upwards or downwards across a vertically mounted touchscreen. In contrast to previous findings, the results suggest that positive pictures were evaluated as more positive after downward movements while negative pictures were evaluated as less negative following upward movements. This finding may indicate that a matching between the pictures’ valence and the valence associated with their vertical touch location leads to more positive evaluations. Thus, the present study extends earlier results by an important point: Touching the emotional pictures during movement may influence their valence processing.