Kidney and hypertension
Authors: Jovanović Dijana 
Published: July 2014

&lt;p&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 888.189px; top: 793.279px; font-size: 13.3333px; font-family: serif; transform: scaleX(1.11265);&quot; role=&quot;presentation&quot;&gt;Whether hypertension is the cause or effect of kidney disease is the long lasting question which has to&lt;/span&gt;&lt;br role=&quot;presentation&quot; /&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 888.189px; top: 809.279px; font-size: 13.3333px; font-family: serif; transform: scaleX(1.11948);&quot; role=&quot;presentation&quot;&gt;be discussed in future. Together these two diseases have become epidemics in present society and are&lt;/span&gt;&lt;br role=&quot;presentation&quot; /&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 888.189px; top: 825.292px; font-size: 13.3333px; font-family: serif; transform: scaleX(1.14126);&quot; role=&quot;presentation&quot;&gt;associated with the increased risk of cardiovascular diseases. Over the last several decades multiple&lt;/span&gt;&lt;br role=&quot;presentation&quot; /&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 888.189px; top: 841.292px; font-size: 13.3333px; font-family: serif; transform: scaleX(1.10391);&quot; role=&quot;presentation&quot;&gt;clinical, experimental and genetic studies have shown the kidney to be an important determinant of the&lt;/span&gt;&lt;br role=&quot;presentation&quot; /&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 888.189px; top: 857.292px; font-size: 13.3333px; font-family: serif; transform: scaleX(1.06808);&quot; role=&quot;presentation&quot;&gt;essential hypertension. However, little is known about the direct mechanisms by which the kidney induces&lt;/span&gt;&lt;br role=&quot;presentation&quot; /&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 888.189px; top: 873.292px; font-size: 13.3333px; font-family: serif; transform: scaleX(1.09568);&quot; role=&quot;presentation&quot;&gt;hypertension or why the blood pressure tends to rise in patients with chronic kidney disease. This paper&lt;/span&gt;&lt;br role=&quot;presentation&quot; /&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 888.189px; top: 889.292px; font-size: 13.3333px; font-family: serif; transform: scaleX(1.11594);&quot; role=&quot;presentation&quot;&gt;described pathophysiology of the essential hypertension and its relationship to chronic kidney disease&lt;/span&gt;&lt;br role=&quot;presentation&quot; /&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 888.189px; top: 905.292px; font-size: 13.3333px; font-family: serif; transform: scaleX(1.13833);&quot; role=&quot;presentation&quot;&gt;and cardiovascular disease. Particular focus has been drawn to effects of the renal sodium handling,&lt;/span&gt;&lt;br role=&quot;presentation&quot; /&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 888.189px; top: 921.292px; font-size: 13.3333px; font-family: serif; transform: scaleX(1.098);&quot; role=&quot;presentation&quot;&gt;renin angiotensin aldosterone system, the sympathetic system, as well as mediators of the vascular tone&lt;/span&gt;&lt;br role=&quot;presentation&quot; /&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 888.189px; top: 937.292px; font-size: 13.3333px; font-family: serif; transform: scaleX(1.11965);&quot; role=&quot;presentation&quot;&gt;in development of kidney-induced hypertension. In addition, the mediators initiating and maintaining&lt;/span&gt;&lt;br role=&quot;presentation&quot; /&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 888.189px; top: 953.292px; font-size: 13.3333px; font-family: serif; transform: scaleX(1.1495);&quot; role=&quot;presentation&quot;&gt;the progression of chronic kidney disease and the interrelation of these factors and development of&lt;/span&gt;&lt;br role=&quot;presentation&quot; /&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 888.189px; top: 969.292px; font-size: 13.3333px; font-family: serif; transform: scaleX(1.11641);&quot; role=&quot;presentation&quot;&gt;hypertension have been discussed.&lt;/span&gt;&lt;/p&gt;