bluuebunny/crossref_metadata_2025 huggingface dataset:
5-Methyl-4-(5-Bromo-2-hydroxyphenyl)-1,3-Dithiolium Derivatives
Authors: Lungu Catalin Neculai , Sandu Ion , Sarbu Laura Gabriela
Published: February 2020

Novel 4-(5-bromo-2-hydroxyphenyl)-5-methyl-2-(N,N-dialkylamino)-1,3-dithiol-2-ylium hydrogen sulphates have been synthesized by the heterocyclisation of the 1-(5-bromo-2-hydroxyphenyl)-1-oxapropan-2-yl dithiocarbamates. The latter compounds have been obtained from the reaction of the corresponding substituted a-bromopropiophenone with various salts of dithiocarbamic acids. These derivatives were characterized by NMR and MS spectrometry, UV-Vis and IR spectroscopy.
Assessment of Clinicopathological Features in Infants and Children with Cow�s Milk Protein Allergy
Authors: Puiu Ileana , Bica Elena Catalina , Dinescu Venera Cristina , Rogoveanu Otilia Constantina , Dan Alexandra Oltea , Vasile Ramona Constantina , Dinescu Sorin Nicolae , Romanescu Florin Marius , Tartea Elena Anca , Tudorascu Diana Rodica
Published: February 2020

The aim of our study was to evaluate the clinicopathological features in infants and young children with cow�s milk protein allergy. Cow�s milk protein allergy (CMPA) is one of the most common food allergy in children. Thus, we conducted a descriptive observational study, which was carried out in the First Pediatric Clinic of the Craiova County Emergency Clinical Hospital, in the period 2015-2017, which included 138 infants and young children diagnosed with cow�s milk protein allergy. An improvement in digestive symptomatology during the status period of the disease was observed, especially in what diarrheal stools are concerned as their incidence has decreased. In fact, gastroesophageal reflux is the most common manifestation in infants and children with CMPA, while mean acute otitis is present only in a small number of patients. In conclusion we can say that a good knowledge of the clinicopathological features in children with allergy to cow�s milk proteins allows a superior therapeutic attitude and ensures a normal life for children and infants suffering from this type of allergy.
The Effect of a Plasma With Platelet-rich Fibrin in Bone Regeneration and on Rate of Orthodontic Tooth Movement in Adolescents
Authors: Nemtoi Ana , Sirghe Ana , Nemtoi Alexandru , Haba Danisia
Published: February 2020

The aim of this study was to evaluate the effect of platelet-rich fibrin (PRF), placed in extraction sockets, on bone regeneration and orthodontic tooth movement in adolescents. Fourty extraction sockets from twenty patients requiring extraction of first premolars based on their orthodontic treatment plan participated in this split-mouth clinical trial. Immediately, the teeth adjacent to the defects were pulled together by a NiTi closed-coil spring with constant force. The bone regeneration and the amount of orthodontic tooth movement was evaluated.
Lateral Extraarticular Tenodesis in Combined ACL and ALL Reconstruction. Case presentation
Authors: Paraschiv Radu , Dinache George , Drignei Marinel , Jovenet Eric , Ferechide Dumitru , Lazarescu Sorin
Published: February 2020

The purpose of this paper was to evaluate the necesity of associating a lateral extraarticular tenodesis in patients that will undergo an anterior cruciate ligament reconstruction or revision and to briefly describe the surgical procedure. Multiple lateral extraarticular tenodesis techniques were described and also graft selection and fixation types are also important. In conclusion acute ACL tears with grade 3+ pivot shift can be succesfully treated by combined ACL reconstruction and LEAT association.
Lung Function and Quality of Life in Workers with Chemical and Dust Exposure
Authors: Otelea Marina Ruxandra , Arghir Oana Cristina , Zugravu Corina , Naghi Eugenia , Antoniu Sabina , Rascu Agripina
Published: February 2020

Regarding the widely distribution of respiratory exposure hazards in occupational settings, workers have an increased risk for chronic lung diseases. For assessing the quality of life and lung function in workers exposed to chemicals and dust, St George�s Respiratory Questionnaire (SGRQ) and spirometry were performed among 40 patients, admitted in Occupational Clinic Department of Colentina Hospital, Bucharest, Romania, during February, 2017. SGRQ showed different predictors for patients according to their occupational exposure and total symptoms score correlated better with decreased spirometric parameters in defining lung function deterioration. Quality of life is earlier affected than lung function deterioration and emphasises the need of more sensitive methods for an earlier identification and better evaluation of respiratory hazards in different workplaces.
Research on Digestibility of the Mulberry Leaf from the Kokuso 21 Variety in Relation to the Dynamics of the Chemical Content
Authors: Dolis Marius Gheorghe , Boisteanu Paul Corneliu , Usturoi Marius Giorgi , Simeanu Daniel , Bodescu Dan , Nacu Gherasim , Usturoi Alexandru , Simeanu Cristina
Published: February 2020

During the growth of silkworm larvae study, also was done a research which aimed to determine the chemical composition and the digestibility of mulberry leaves from a Japanese variety, Kokuso 21. The results showed that advancing in the vegetation stage at the same time with different periods of the silkworm larvae�s growth, the mulberry leaves experience an aging process being noticed through its quality decreasing from chemical composition point of view. Accordingly, with this, to the majority of nutrients from mulberry leaves, except the crude fiber was noticed a continuous digestibility decreasing throughout larval growth period So, for example, digestibility of crude protein decreased gradually throughout the studied period, with 27.11%, respectively from 84.42% at the first chemical determination to 61.53% at the last one. The nutrients digestibility from the leaves registered in average a value of 55.87%.
Heavy Metal Pollution Affects the Antioxidant Potential of Rosa canina L. Species
Authors: Ciornea Elena Todirascu , Dumitru Gabriela , Zaharia Marius , Drochioiu Gabi , Sandu Ion
Published: February 2020

The content of vitamin C, carotenes, polyphenols, total carbohydrates and total soluble proteins was determined, alongside with the activity of the oxidative stress enzymes (superoxide-dismutase, catalase, peroxidase, isocitrat-dehydrogenase, ketoglutarat-dehydrogenase, succinat-dehydrogenase and malat-dehydrogenase) in Rosa canina L. samples collected from the heavy metals and arsenic polluted area around of Tarni�a closed mine, as well as from Sucevita area (as unpolluted site). The results showed an increase in the rose hip richness of nutrients and biological-active compounds, as well as the antioxidant activity of the samples from Tarnita area.We have explained our results taking into consideration the response of rosa plants to the oxidative stress produced by the accumulation of reactive oxygen species generated byexposure to pollutant factors from the contaminated area.
The Importance of Modified Budin Incidence in the Radiological Diagnosis in Patients with Aseptic Necrosis of the Femoral Head
Authors: Patrascu Alexandru , Savin Liliana , Mihailescu Dan , Greierosu Carmen , Grigorescu Victor , Zlate Teodor , Duceac Letitia Doina , Stafie Liviu , Botez Paul
Published: February 2020

This study included 56 patients who presented hip pain occurring spontaneously without any trauma history. A new radiological protocol was initiated for all the patients suspected of NACF. A pelvis, Dunlop profile and modified Budin at both hips scan was performed. In order to emphasize the effectiveness of the new radiological protocol, the following indicators were analyzed: the mobility of the affected hip, the radiological changes typical to the aseptic necrosis of the femoral head, the extension angle of the necrosis area on every incidence after Kerboul [1,2], the surface area covering the necrosis zone on every incidence and the coverage on every patient. The modified Budin profile has a greater diagnostic value for the early stages of NACF than the Dunlop profile and the radiography. The Budin incidence is important in order to differentiate stage III of NACF from stage IV by highlighting the degenerative changes in the acetabular cavity.
Weight of Pregnant Women and their Influence on Second Trimester Biochemical Markers
Authors: Szasz Florin , Levai Codrina , Navolan Dan , Farcas Simona , Andreescu Nicoleta , Birsasteanu Florin , Mehedintu Claudia , Ionescu Cringu Antoniu , Bohiltea Roxana , Carabineanu Adrian , Nemescu Dragos , Simu Sebastian , Stoian Dana
Published: February 2020

Fetal aneuploidies screening was based for a long time on ultrasonographic and biochemical markers measurement. The risk calculated in accordance with second trimester biochemical markers (STBM) values relies on calculation of corrected MoM values. MoM (multiple of Medians) signify the deviation of a measured value from the expected value (Median). The Median is measured at the same gestational age in pregnancies which involve healthy fetuses. The correction of MoM includes an adjustment for certain parameters that influence the STBM value: demographical (ethnicity), behavioral (smoking status, weight), and others (mode of conceiving, etc.). In our article we aim to analyze: (1) the accuracy of software to calculate STBM corrected MoM values, (2) the effect of weight of pregnant women on STBM and (3) the capability of software to counterbalance this influence. Pregnant women (n=1242) were screened for aneuploidies based on an integrated test: first trimester ultrasound and STBM (AFP, hCG and uE3). The absolute value, multiple of median (MoM) and corrected multiple of median (MoMc) values were 33.94�0.45, 1.04�0.12 and 0.98�0.01 for AFP, 22530�477, 0.87�0.01 and 0.85�0.01 for hCG, respectively 0.97�0.03, 0.99�0.01 and 0.98�0.01 for uE3. The weight of pregnant women inversely correlates with absolute and MoM AFP, hCG and uE3 values. No correlation was found with AFP and hCG MoMc values. A very weak inverse correlation was found between weight and uE3 corrected MoM values. Our study confirms that there is a difference between provider and own calculated hCG MoMc values. The weight of pregnant women inversely correlates with STBM values. The software used for aneuploidies risk evaluation corrects the influence of weight of pregnant women, but a minimal influence on uE3 corrected MoM values is still present.
Study About the Precision of Surgical Guides Used in Implantology
Authors: Mihai Ionut Daniel , Mihai Roxana , Vartolomei Claudiu , Comaneanu Raluca Monica , Coman Stefania , Ghergic Doina Lucia
Published: February 2020

The purpose of this study was to detect the precision of inserting dental implants using 3 types of surgical guides on 3 groups of patients according to the degree of implantologist experience. In this study, 27 patients were taken, in 3 groups of 9 patients, who addressed to dental offices in which were implantologists with 1 year (group A), 6 years (group B) and 11 years (group C) of experience in surgery. Lot A, operated by a 1-year physician with experience in implantology, had the smallest deviation, demonstrating the increased attention that he had to the interventions. Comparing B and C lots, the smallest deviations were recorded for group C, operated by implantologist with greater experience in implantology. By comparing the deviations according to the type of surgical guide used, the smallest deviations at the apex and prosthetic platform were made in patients where the implants were inserted with a bone supported guide, followed by dental-gingival and mucosal guide. In terms of axis of implantation, the lowest values were recorded for the dental-gingival guide, followed by the bone and mucosal guide. The study has a number of limitations (low number of patients undergoing study, low dispensation period), which requires more extensive future studies to validate the results.
Acetic Acid and Lugol Tests in Colposcopic Assessment and Surgical Management of Cervical Intraepithelial Lesions
Authors: Berceanu Costin , Mehedintu Claudia , Berceanu Sabina , Paitici Stefan , Ciortea Razvan , Bratila Elvira , Cirstoiu Monica Mihaela , Navolan Dan , Hainarosie Razvan , Bohiltea Roxana Elena
Published: February 2020

Colposcopy is used predominantly to evaluate women with abnormal Babes - Papanicolaou test results, to locate abnormal appearing epithelium and to direct biopsies as well as the surgical management, in areas in which cervical intraepithelial neoplasia is suspected. The purpose of our study is to analyze the value of acetic acid and Lugol tests in the colposcopic assessment and surgical management of cervical intraepithelial neoplasia, and to evaluate the patient outcome after uterine cervix surgery, by postoperative colposcopic determination of the disease-free resection margins
Hyponatremia in Patients with Heart Failure: a Prognostic Marker
Authors: Diaconu Camelia Cristina , Manea Maria , Iancu Mihaela Adela , Stanescu Ana Maria Alexandra , Socea Bogdan , Spinu Dan Arsenie , Marcu Dragos , Bratu Ovidiu Gabriel
Published: February 2020

Due to the high prevalence of cardiovascular diseases and better treatment strategies, with increased survival, heart failure is a condition with increasing prevalence, especially in developed countries. Heart failure patients often present electrolytic disorders, the most frequent one being hyponatremia. The objective of the study was to evaluate the frequency of hyponatremia in patients with chronic heart failure hospitalized in the Internal Medicine Clinic of the Clinical Emergency Hospital of Bucharest and to assess the clinical and paraclinical correlations, as well as prognostic implications of hyponatremia in these patients. We performed an observational retrospective study on 400 chronic heart failure patients hospitalized between January 1st 2014 and August 31st 2015. From these patients, 60 patients have been diagnosed with hyponatremia (defined as a serum natrium [135 mEq/L) and represented our group of study. The values of the serum natrium at admission in the study group ranged between 110-132 mmol/L. Most patients had advanced heart failure, according to NYHA classes� classification. The proportion of patients discharged with persistent hyponatremia was 48.33%, lower than the patients discharged with corrected serum sodium (51.67%), indicating an effective treatment of hyponatremia during hospitalization. The mortality rate during hospitalization in patients with corrected hyponatremia was 8.33%, smaller than the mortality rate in patients with persistent hyponatremia despite the correct administration of hydroelectrolytic rebalancing treatment (18.33%). Persistent hyponatremia may be considered a marker of a poor prognosis in hospitalized heart failure patients.
A Comparative Evaluation of Serum and Salivary Total Proteins and Immunoglobulins in Patients with Hepatitis A and Healthy Subjects
Authors: Balan Daniela G. , Sianu Dan Piperea , Stanescu Iulia I. , Ionescu Dorin , Stroescu Balcangiu Andra Elena , Raducu Laura , Stoicescu Silvia Maria , Ceau Adela M. , Tiliscan Catalin , Nimigean Vanda Roxana , Tarmure Viorica , Croitoru Alexandru G.
Published: February 2020

Assessment of changes in total proteins level, serum and saliva IgG and IgA levels, serum IgM level, serum and saliva IgA/IgG ratio. The study was conducted on a group of 40 subjects, divided into 2 lots: the first lot consisting of 20 healthy individuals and the second consisting of 20 patients with hepatitis with hepatitis A virus (HAV). The levels of total proteins, serum and saliva IgG and IgA, serum IgM and serum and saliva IgA/IgG ratio have higher values in patients with hepatitis A, in comparison to healthy subjects, without necessarily exceeding the maximum admitted value. The results are significant from a statistical point of view. Due to the sensitivity and specificity of salivary anti-HAV IgM and IgG in patients with acute hepatitis A, compared with healthy subjects, there is a possibility of using salivary immunological tests instead of serum tests for the diagnosis and epidemiological study of HAV infection.
Combined Approach of the Anterior Skull Base in Sinonasal Tumours
Authors: Palade Dragos Octavian , Cobzeanu Bogdan Mihail , Zaharia Petronela , Dabija Marius
Published: February 2020

Malignancies of the nasal cavity and the paranasal sinuses are rare, counting for less than 3 % of the ENT-cancers. The insidious onset of these tumours with non-specific symptoms often leads to a delayed diagnostic. Advanced disease stage combined with the complex anatomy of the sinonasal cavities and anterior skull base encouraged surgeons to extend beyond the boundaries the classic surgical techniques. Surgical approaches to anterior skull base lesions can be divided into open approches: craniofacial, subcranial, endoscopic techniques or combined approaches when a craniotomy is associated with an endonasal endoscopic approach. The indication must take into consideration the oncologic principles, histopathology exam, extent of disease and surgeon skill and experience. Combined approach should be taken into consideration for patients with extended disease or significant intraorbital or intracranial extension. For certain tumours that require a craniotomy for the superior, superolateral, and anterior extensions of the disease and also a nasal and paranasal sinus tumor that could be removed endoscopically, an endoscopic-assisted approach can be considered.
Body Mass Index, Self Weight Perception and the Intention of Changing the Weight in Teens of 11-18 Years
Authors: Simbrac Mihaela Cristina , Putnoky Salomeia , Mladinescu Corneluta Fira , Bagiu Radu , Sas Ioana Tuta , Bacean Miloicov Codruta , Brancoveanu Ana Maria , Suciu Oana , Folescu Roxana , Buzatu Roxana , Vlaicu Brighitha
Published: February 2020

The research intends to investigate the body mass index, the self-weight perception and the intention of changing the weight in teenagers, from Timisoara, Romania. The data sample was made of 243 students of 11-18 years old: 37.9% in middle school and 62.1% in high school; 56.4% girls and 43.6% boys. The manner of work was a cross-sectional study, study case type. The results show that in middle/high school there are: underweight 39.8%/22.9%, normal weight 51.1% and overweight and obese, 9.1%/8.3, with a significant difference between the 2 age groups, the difference being very small. 62.2% of middle school students and 51.7% of the ones in high school appreciate their own weight as having the normal value. 24.4% of the middle school students and 32.4% of high school students consider that that they have a weight over the normal value, and at 15-18 years old, girls perceive weight as being significantly higher than boys. The students want to lose weight, 42.7% of middle school students and 42.8% of high school students. At 11-14 years old, boys want to gain weight more frequently than girls.
Study of Electrochemical Behavior of Some Dental Alloys
Authors: Pendefunda Alice Arina Ciocan , Mocanu Constanta , Agop Forna Doriana , Iordache Cristina , Luca Elena , Ifteni Gabriela , Forna Consuela Norina
Published: February 2020

The purpose of the study is to investigate the electrochemical behavior of two dental alloys: palladium alloy (Palidor) and Ni-Cr alloy (Verasoft) in three types of artificial saliva. Determination of corrosion potential and recording of linear and cyclic polarization curves were performed with PGP201 potentiostat (VoltaLab 21- Radelkis Copenhagen. In order to study the modifications produced on the surface of the electrodes, a complex optical microscope MC 1 research type (IOR, Romania) was used, adapted to a digital camera, which was connected to a computer for the digital acquisition of images . Two metal alloys based on Ag-Pd and Ni-Cr were used for the experiments. The materials used came from different types of dental restorations removed from the oral cavity of the patients after a 5-15 years period. As corrosion environments, three artificial saliva were used: Fusayama, Afnor and Rondelli. The Pd-Ag dental alloy exhibits a very good corrosion resistance and the treatment in the Afnor saliva does not affect the surface of the alloy. Electrochemical behavior in Fusayama-Meyer�s saliva of the alloy surface results in a series of spots representing deposits of insoluble salts resulting from the oxidation process, while in the Rondelli saliva there is a series of small corrosion points on the alloy surface. The behavior of the Verasoft alloy in the Afnor and Rondelli saliva is similar; In both solutions, the potential breakthroughs are very close, but in Fusayama-Meyer�s saliva, the potential for initiation of corrosion points is very low (206 mV), a potential that can be encountered in the oral cavity. All metals and metal alloys, even the noble and semi-precious ones, are susceptible to corrosion, forming compounds with properties different from those of the metal or base alloy, which change their surface condition. Metallic dental restorations are permanently affected by the factors of the oral environment (physical-mechanical, chemical and biological), being subjected to a continuous process of degradation.
Experimental Survey Regarding the Dangerous Chemical Compounds from Military Polygons that Affect the Military Health and the Environment
Authors: Ginghina Nicoleta Petrea Raluca , Pretorian Andrada , Petre Razvan , Barsan Ghita , Otrisal Pavel , Mosteanu Danut Eugeniu
Published: February 2020

Activities specific to the military field, regarding the instruction process or the missions in the operating theatres, require military personnel to be exposed to a series of toxic chemical compounds, with effects ranging from short to long term. European legislation regarding environmental protection and employee health has become stricter and it directly influences the choice of materials that will be turned into ammunition. Most energetic materials from ammunition contain compounds whose synthesis and decomposition involves the release of high toxicity products into the environment. Shootings with classical weapons systems have an effect on the environment, in the shooting area and also in the place of impact with the objective, having both direct (the shock wave that results from the ammunition exploding, shrapnel, sound waves, high temperatures) and indirect (unexploded ammunition, contamination of the environment) effects. This paper presents the results of experimental research conducted in military shooting ranges during the testing of diverse smoke ammunition, in order to detect and identify the released chemical compounds, thus studying their impact on the fighters� health and security and evaluating the risks they pose on the environment.
Use of Synthetic Protetic Materials in Surgical Abdominal Defects. Analysis of the Advantages and Lack of the Liechtenstein Method
Authors: Baleanu Vlad Dumitru , Constantin Denis Vlad , Pascal Anca , Alexandru Dragos Ovidiu , Bobic Simona , Socea Bogdan , Manda Ana Laura , Davitoiu Dragos , Dijmarescu Anda Lorena , Georgescu Ion , Mirea Cecil Sorin
Published: February 2020

Liechtenstein procedure represents the most frequent technique used for surgical abdominal interventions. Although, it is a modern and inovative procedure, it still has a relative risk for complications. A number of 93 subjects were included in our research. We develop our study in General Surgery Department of County Emergency Hospital of Craiova, Romania between 1st July 2017-31th March 2018. From the total of 93 patients, 88% were men. Most of subjects had ages between 70 and 79 years old, were operated by Liechtenstein technique and they were coming from quite equal percent from rural and urban areas.The incidence for complications(seroma, hematoma, infection, abscess) was generally lower for the patients diagnosticated with Liechtenstein procedure comparing with the subjects operated by other technique. Liechtenstein procedureis recommended especially for its simplicity and efficiency, reproducibility and safety. It is very important to choose the perfect synthetic prosthetic material to have a good evolution of the disorder and a small recurrence rate.
Chemical Ablation of Cartilagineous Tissue in Tracheal Stenosis
Authors: Ionita Irina Gabriela , Zainea Viorel , Stefanescu Cristian Dragos , Pietrosanu Catalina , Hainarosie Mura , Pituru Silviu , Rusescu Andreea , Diaconu Camelia Cristina , Hainarosie Razvan
Published: February 2020

Laryngo-tracheal stenosis represents a challenging pathology that requires multi-stage surgical approach, and a multidisciplinary team. The diagnosis is based on clinical examination, endoscopic assessment, and imagistic evaluation. Coblation is a surgical technology based on chemical ablation of the tissue, that is suitable for tracheal stenosis approach.We present our experience with coblation for the management of laryngo-tracheal stenosis, and highlight the advantages, and disadvantages of coblation for tracheal stenosis.
We consider chemical ablation of the cartilaginous tissue through coblation a valuable surgical technology for the treatment of tracheal stenosis.
Influence of Temperature on the Growth of Silver Nanoparticles Synthesized Using Salvia officinalis Aqueous Extract
Authors: Bumbac Marius , Olteanu Radu Lucian , Ion Rodica Mariana , Nicolescu Cristina Mihaela
Published: February 2020

In this paper the silver nanoparticles (AgNPs) are synthesized by bottom-up approach using Salvia officinalis aqueous extract as reducing agent, and under such circumstances, the ultraviolet-visible (UV-Vis) spectroscopy is used to evaluate the evolution of the synthesis process, scannings in the wavelength range of 230 nm to 750 nm. The presence, position and shape of the absorption maximum in the region of 400-430 nm were monitored, and associated with AgNPs formation . Interactions of organic substrate with the generated silver nanoparticles were put into evidence by using infrared spectroscopy. The experiments were conducted at four temperatures and five different volumetric ratios of AgNPs precursors, the plant extract and silver nitrate 10 mM aqueous solutions. Conclusions on the synthesis parameters effect on process evolution were drawn. It was found that the temperature and the initial ratio of synthesis precursors influence the growth process and characteristics of the obtained AgNPs. Infrared spectra confirmed the interactions between the organic substrate and the formed AgNPs, as well as with nitrate ions present in the synthesis mixture. Thus, the position and the shape of the recorded peaks in the ranges 1500 - 1600 cm-1, 800 - 900 cm-1 and around 3400 cm-1 showed significant changes during the nanoparticles synthesis.
The Influence of the Ash Addition from Thermal Power Plant on the Mechanical, Thermal and Dielectric Characteristics of Mortars
Authors: Velciu Georgeta , Marinescu Virgil , Moanta Adriana , Radermacher Ladislau , Bors Adriana Mariana
Published: February 2020

The influence of fly ash adittion (90 % fraction [ 100 mm) on the cement mortar characteristics was studied. The XRD, XRF, SEM and FTIR determinations indicated that fly ash used has a hollow microstructure of microsphere and cenosphere whose total content in SiO2, Al2O3 and Fe2O3 is 88.63 % and that of CaO and MgO of 8.55 %. The mechanical, thermal and dielectric determinations made on mortar samples with content of fly ash in the 0-40 % range have highlighted fact that the mechanical strength of cement mortars is maximal at 20 %, the increase in fly ash content leads to a decrease in relative density and thermal conductivity as well as and to increased dielectric losses tgd.
Lung Delayed Hypersensitivity. A case with particular features
Authors: Prodea Mihaela , Boia Eugen Radu , Ceausu Raluca Amalia , Librimir Cosmin , Iovanescu Gheorghe , Mederle Ovidiu Alexandru
Published: February 2020

Delayed hypersensitivity reactions are inflammatory reactions initiated by mononuclear leukocytes. These reactions are mediated by T cells and monocytes/macrophages rather than by antibodies. We describe a case of 50 years old man with lung type IV hypersensitivity. The case of lung delayed hypersensitivity presented has some particular histopathological and immunohistochemical features. The diagnosis of lung delayed type hypersensitivity requires analysis of correlation between clinic, radiographic, physiologic and pathologic criteria.
Structural and Magnetic Relaxation of Fe61Co10Y8Mo1B20 Bulk Amorphous Alloy Obtained Using Two Methods
Authors: Pietrusiewicz Pawel , Nabialek Marcin , Jez Bartlomiej
Published: February 2020

Bulk amorphous Fe61Co10Y8Mo1B20 alloys in the form of plates have been prepared using two methods: suction casting and injection casting. The structure of the as cast samples have been studied using Mossbauer spectroscopy. The obtained Mossbauer spectra are typical for materials of amorphous structure. In the hyperfine field distributions obtained from the Mossbauer spectra analysis, there are variations between the probability of occurrence of magnetic atoms around central atom. Then, magnetic susceptibility disaccommodation has been measured for the tested samples. These measurements indicate that the structural relaxation in the studied samples occur at the elementary level. Injection casting method for the tested alloy determines, in the material volume, the formation of more point relaxators in the form of free volume.
Quality by Design (QbD) Approach to Develop and Validate a HPLC Method for Piroxicam from Serum
Authors: Spac Adrian Florin , Miftode Alina Monica , Asaftei Iuliean Vasile , Sandu Ion
Published: February 2020

Piroxicam belongs to the non-steroidal antiinflammatory class, it is utilized as analgesic, anti-inflammatory and antipyretic. A simple and accurate HPLC method was optimized and validated in the QbD approach, for the determination of piroxicam in serum. The optimization of HPLC analysis was performed using different columns, mobile phases and flows. The HPLC method was appropriately validated for linearity, limit of detection, limit of quantification, precision and accuracy in accordance with the ICH guidelines. The optimized and validated method proved to be simple, precise, and accurate, and can be successfully applied for the determination of piroxicam in serum.
Reconstruction of Severe Acetabular Bone Defects in Revision Hip Arthroplasty Management options and clinical outcomes
Authors: Mogos Stefan , Viscopoleanu George , Dascalu Monica , Orfanu Radu
Published: February 2020

The objective of this study was to evaluate the effectiveness of different surgical implants for the reconstruction of severe acetabular bone defects in revision arthroplasty of the hip. The current study is a retrospective study on 32 patients with Paprosky type IIIA or IIIB acetabular defects operated between January 2012-December 2015 in a single hospital. The mean follow-up was 21 months (12-43 months). Five different types of reconstruction methods were used: primary uncemented cups with or without screws, cemented acetabular cups, tantalum cups, metal augments and antiprotrusio cages. Bone allograft was available in all cases. Functional outcome after surgery was evaluated using Harris Hip Score. Based on Paprosky classification, the study included 16 type IIIA and 16 type IIIB acetabular defects. Bone graft was used in 71.8% of the cases (23 out of 32 patients). Tantalum cups were used in 15 cases (46.9%), being the preferred implant. Primary uncemented cups were used in 2 cases, cemented acetabular cups were used in 4 cases, trabecular metal augments were used in 5 cases and antiprotrusion cages were used in 6 cases. The mean Harris Hip Score improved from 37.3�7.4 pre-operatively to 82.1�7.2 at final follow-up. In conclusion, the current study demonstrates that various methods of reconstruction are efficient in the short and medium-term.
Comparative Study by Analytical Multidisciplinary Methods and Oxidative Stress in Breast Cancer Diagnosis
Authors: Jari Irina , Naum Alexandru , Moisii Liliana Gheorghe , Stefanescu Cipriana , Negru Dragos , Ursaru Manuela , Ciuntu Bogdan Mihnea , Timofte Daniel
Published: February 2020

To evaluate the diagnostic performance of mammography, elastography and breast magnetic resonance imaging (MRI), as tools for breast cancer diagnosis, against pathological diagnosis as the gold standard. Other risk factors such as obesity and oxidative stress are also disccused. In this comparison study, a total of 169 female patients (mean age 51 years, range 35-77 years) were enrolled between January 2016 and June 2017. After the physical examination of the breasts, patients were further randomized into three groups to mammography, elastography, or breast MRI. Only women with detected lesions classified into breast imaging and reporting data system (BI-RADS) category or Tsukuba elasticity score from 2 to 5 were included. Histopathology was used as the gold standard for diagnosis. The diagnostic performance of each modality was calculated. Of a total of 50 pathologically confirmed cancers, 25 were detected by mammography, 11 by elastography, and 14 by breast MRI, which resulted in sensitivities of 84% (PPV = 78%), 75% (PPV = 64%) and 86% (PPV = 75%), respectively. Mammography, elastography, and breast MRI led to 6, 5, and 4 false positive findings, which resulted in specificities of 86% (NPV = 90%), 87% (NPV = 92%) and 89% (NPV = 94%), respectively. The area under the curve (AUC) values for the mammography, elastography and breast MRI were 0.849 (95% CI, 0.758-0.939), 0.809 (95% CI, 0.670-0.948) and 0.876 (95% CI, 0.769-0.983). The DOR values were 32 (95% CI, 8-125), 20 (95% CI, 4-99) and 51 (95% CI, 8-315). The breast MRI proved a slight advantage over mammography as a diagnostic tool in breast cancer diagnosis.
Paranasal Sinus Mucocele Clinical, imagistic and biochemical aspects
Authors: Vesa Doina , Martu Cristian , Leata Razvan , Lozneanu Ludmila , Radulescu luminita , Stoica George , Ganea mihai , Zaharia Aurelia , Chipirliu Oana , Luchiancenco Delia Cristina , Racovanu Anca , Laza Georgeta Maria , Pavel Liliana
Published: February 2020

Paranasal mucoceles are a type of cysts that evolve slowly and are asymptomatic; this poses a difficulty in diagnosing the patient because the symptoms can go unnoticed. The mucocele evolves unpredictably. On the one hand, it can become infected turning into pyoceles and on the other hand, it can invade important regions such as the orbital, cranial or genian regions, creating facial asymmetry. This is a retrospective case study of 37 patients diagnosed with sinus mucoceles, followed up by clinical examination and paraclinical tests such as CT and MRI scans. The biochemical components of the liquid from within the mucocele were analyzed and the following criteria were recorded: NaCl-, Cl-, Na+ and cholesterine as well as cellular components such as mastocytes, macrophages, hematocytes and leucocytes. In all cases, the treatment option was surgery with favorable post-operative and follow-up evaluation. The mucoceles that appeared post-operatively (maxillary and ethmoid sinuses) evolved more rapidly than the mucoceles that were induced byan external injury. Longer follow-up of operated patients permitted a more timely diagnosis of recurrences.
Chemical Study of Antibiotics in Treatment of Non-secfic Perimaxial Suppurations in Pregnancy
Authors: Constantin Mihai , Budacu Cristian Constantin , Pavel Liliana , Rosu Sorana , Caraiane Aureliana
Published: February 2020

Physiological changes caused by pregnancy favor the onset or aggravation of preexisting buccal dental lesions, which, untreated, may evolve into infectious complications. Perimaxilation should be treated immediately due to the risk of infection spread or disseminated at a distance. Pain relief is an important reason for immediate treatment, as the particular state of nervousness can trigger a neuro-hormonal reflex followed by a break in pregnancy. The treatment of perimaxial suppositions involves two main aspects: surgical management and medical management. Surgical management will apply as well as outside the pregnancy, recommending local or loco-regional anesthesia with 2% xylin and vasoconstrictor at very low doses. In medical management, it should be noted that the upcoming mother�s ingestion of various drug substances is a matter of maximum responsibility. Drug administration during pregnancy should be an exceptional attitude, but strict application of this principle could deprive pregnant women of the use of useful drugs resulting in maternal complications and embryo-fetal suffering. The study is a retrospective and was performed on a batch of 70 pregnant women who presented themselves in the Oral and Maxillofacial Surgery Clinic during 2014-2017, presenting perimaxial suppurations.Surgical treatment (opening and evacuation of the purulent collection), performed in all patients, was preceded by anesthesia, local or loco-regional. Preventive dental care should prevail over curative care in the case of dental treatments of women pregnant women, because all physiological changes caused by pregnancy aggravate the pre-existing oro-dental lesions. Prophylactic attitude will not allow the emergence of infectious complications of dental origin.
BIiochemical Markers in Pregnancy Associated with Sj�gren�s Syndrome and Thrombophilia
Authors: Braila Anca Daniela , Neacsu Adrian , Musetescu Anca Emanuela , Vircan Elena Luminita , Florescu Alesandra , Bumbea Ana Maria
Published: February 2020

Sj�gren�s syndrome (SS) is a multisystemic disease mainly characterized by the hypofunction of the lachrymal and salivary glands and can be either primary or secondary, when related to other autoimmune pathologies.
We present the case of a 35-year-old female admitted in the Department of Obstetrics and Gynecology for pregnancy monitoring. The patient had a personal history of a spontaneous abortion one year prior to admission at 5 months of gestation and a maternal history of SS. A multidisciplinary approach with solid obstetrical, rheumatological and neonatal monitoring is essential for best outcomes of the mother and fetus. An early detection of maternal and fetal immune-mediated threats and judicious use of medication is essential in women with autoimmune diseases who plan conceiving.
Flow Cytometry With Inflorescence-An Accessible Method in the Study of Qualitative and Quantitative Modifications of Blood Platelets in Immune Thrombocytopenic Purpura
Authors: Badulescu Oana Viola , Badescu Magda , Ciocoiu Manuela , Mocanu Madalina
Published: February 2020

The immune thrombocytopenic purpura (ITP) is a polymorphic and hematologic pathology, in terms of both clinical manifestations and etiopathogenic mechanisms, which bring on this disease. Establishing the type of thrombocytopenia, which can either be primary or secondary, peripheral or central, is essential for a further proper therapeutic conduct. The current means of diagnosis include a large variety of hematologic, immunologic and biochemical explorations, from the traditional ones to the latest methods, either genetical or molecular. The purpose of this paper is to emphasize the importance of a classical method of diagnosis, used in the primary triage of patients suffering from thrombocytopenia, highly valuable in the diagnosis process: the analysis of the mean platelet volume (MPV) and of the platelet distribution width (PDW), parameters revealed by the CBC (complete blood count). Evaluating the size of the platelets is a useful tool in the differential diagnosis between immune thrombocytopenic purpura and hereditary macrothrombocytopenia. The platelet distribution width and the mean platelet volume are read simultaneously, in order to differentiate the immune peripheral thrombocytopenia from the central one. The classical, viable and accessible method facilitates the measurement of MPV and PDW with the automatic analyzer, which functions according to the principle of flow cytometry with inflorescence, by using a LASER semiconductor and hydrodynamic focusing.
Corrosion of Welded Metal Structures of Mining Equipment
Authors: Dobrota Dan
Published: February 2020

Mining equipment made of welded metal structures is strongly affected by the corrosion phenomenon due to the working conditions. Initial research has shown that the corrosion phenomenon is most pronounced in the area of cross-welded joints and welded T-shaped joints. In the researches, there was made a chemical analysis of the welded construction material used respectively of the new material and it was observed a reduction in carbon concentration in the material used, but also a substantial increase in the sulfur concentration compared to the new material. The pronounced corrosion of the metallic structure is influenced by the chemical composition change because the sulfur is a grafitizing and weakening element, and the decrease in carbon concentration causes a decrease in corrosion resistance. Also, the pronounced corrosion is due to the action of sulfurous acid (H2SO3) and hydrogen sulfide (H2S), elements that are present in the working environment of welded constructions. In order to achieve a reduction in the corrosion phenomenon, it is very important that the welded joints are made using the optimal parameters of the welding regime so as to obtain metallographic structure with finer granulations.
ДІЯЛЬНІСТЬ РАДИ МОЛОДИХ УЧЕНИХ: ПРОБЛЕМИ, РИЗИКИ, ПЕРСПЕКТИВИ
Authors: Hubeladze Iryna
Published: February 2020

У доповіді представлено основні напрями діяльності та здобутки Ради молодих вчених Національної академії педагогічних наук України, серед яких: захист і сприяння реалізації прав та інтересів молодих учених підвідомчих установ НАПН України, підтримка і супровід молодих учених у їхньому професійному становленні, вдосконалення іншомовної компетентності, підвищення компетентності з використання ІКТ, зокрема і платформ Web of Science, Scopus, Open Ukrainian Citation Index, проведення міждисциплінарних досліджень, презентації себе у світовому науковому просторі, відстоювання принципів академічної доброчесності, взаємодія з громадськістю, співпраця молодих вчених всередині НАПН України та з Радами молодих вчених НАН України, МОН України, Державного науково-дослідного інституту МВС України і національних галузевих академій України. Окреслено деякі проблемні питання, а саме необхідність посилення і фінансової підтримки міжнародної діяльності молодих вчених, підтримки наукової молоді, підвищення престижності наукової діяльності серед населення, популяризації наукової діяльності серед молоді, необхідність зосередження істотної частини державного замовлення на підготовку психологічних кадрів за докторськими і магістерськими програмами у наукових установах психологічного профілю, загрозливу тенденцію до зменшення державного замовлення і зменшення фінансування підготовки докторів філософії та докторів наук.
ПРО НАУКОВУ І НАУКОВО-ОРГАНІЗАЦІЙНУ ДІЯЛЬНІСТЬ ІНСТИТУТУ ПЕДАГОГІЧНОЇ ОСВІТИ І ОСВІТИ ДОРОСЛИХ ІМЕНІ ІВАНА ЗЯЗЮНА НАПН УКРАЇНИ ЗА 2015-2019 рр. ТА ПЕРСПЕКТИВИ РОЗВИТКУ
Authors: Lukianova Larysa
Published: February 2020

У доповіді представлено інформацію щодо кадрового складу Інституту педагогічної освіти і освіти дорослих імені Івана Зязюна НАПН України та динаміку його змін у звітному періоді. Представлено результати науково-організаційної діяльності Інституту за п’ятьма обґрунтованими індикаторами (участь у розробленні законодавчих і нормативно-правових актів в освітній галузі; участь у реалізації державної політики в освітній сфері; міжнародна співпраця; здійснення наукової консультативно-дорадчої діяльності; соціально-мережева діяльність) з відповідними показниками, що мають вияв на трьох рівнях (загальнодержавному, академічному, інституційному). Розкрито результати експериментальної роботи у звітному періоді та зазначено кількість одиниць планової продукції, підготовленої до впровадження; конкретизовано обсяг наукових статей, опублікованих у зарубіжних виданнях (13,6 %), виданих іноземними мовами (7 %) та у Scopus, Web of Science Core Collection (близько 5 %).Доповідачем розкрито зміст діяльності Центру освіти дорослих та його підструктур, що працюють на базі Інституту; описано результати співпраці із закладами вищої освіти, а також діяльність кафедри ЮНЕСКО «Неперервна професійна освіта ХХІ століття» та Ради молодих науковців, місією якої є «наука в дії»; описано напрями, які потребують більшої уваги, й висвітлено перспективи розвитку Інституту.
Triplocania Roesler, 1940: new record for Triplocania rosae Silva-Neto, García Aldrete & Rafael, 2016 and proposal of a new infrageneric group (Psocodea, ‘Psocoptera’, Ptiloneuridae)
Authors: Silva-Neto Alberto M. , Garcia Aldrete Alfonso N.
Published: February 2020

In this work a new record for Triplocania rosae Silva-Neto, García Aldrete & Rafael, 2016 in the Brazilian state of Minas Gerais was made, and also a propose for a new species group in Triplocania, with an identification key to the species in it.
New Records of Syscia Roger, 1861 (Hymenoptera: Formicidae: Dorylinae) in South America
Authors: Fernandes Itanna O. , Souza Jorge L. P.
Published: February 2020

There are 11 genera of Dorylinae in the Neotropics, but Syscia Roger, 1861 is the only one with a discontinuous distribution between the Nearctic, Neotropical and Indomalayan regions. The present study reports a new record of Syscia in northern Brazil and confirms its distribution in South America, in accordance with previous reports. The Syscia specimens corresponds to an undescribed species and were collected along the margins of the Madeira River, in the National Forest of do Jamari, in the southwestern Brazilian Amazon.
DURABILITY STUDY ON FLY ASH BASED GEOPOLYMER CONCRETE FOR ACIDIC ENVIRONMENT
Authors: L. Hake Sandeep , Awasarmal P. R. , Damgir R. M.
Published: February 2020

The production of cement is harmful to the environment. It is important to decrease the creation of Ordinary Portland Concrete. On the opposite side, the thermal power plant expends hectares of land for the dumping of fly fiery remains which is waste material. This paper concentrates on low calcium fly ash based geopolymer concrete. In the geopolymer concrete, the diverse centralization of sodium hydroxide, for example, 8, 10, 12, 14, 16, 18, and 20 molars was utilized. The sodium silicate to sodium hydroxide proportion kept up as 2.5. The eight rate convergence of sulfuric and hydrochloric acid were utilized for the corrosive assault on fly ash based geopolymer concrete. The test perform for oven and steam cured fly ash based geopolymer concrete. The streamlined level of warming utilized for various curing techniques. After the curing, the cube kept in sulfuric and hydrochloric acidic condition for up to the half year. The acidic impact assessed at once interim of 0, 45, 90, 135, 180 days. It is watched that the sulfuric corrosive is unsafe to the fly powder based geopolymer concrete as contrast with hydrochloric corrosive. The cube sample cured for oven and steam curing. The optimized degree of heating used for different curing methods. After the curing, the cube sample were kept in sulfuric and hydrochloric acidic environment for up to the six months. The acidic effect evaluated at a time interval of 0, 45, 90, 135, 180 days. It is observed that the sulfuric acid is harmful to the fly ash based geopolymer concrete as compare to hydrochloric acid.
Domain-Specific Search Engines for Investigating Human Trafficking and Other Illicit Activities
Authors: Kejriwal Mayank
Published: February 2020

Web advertising related to human trafficking (HT) activity has been on the rise in recent years. Question answering over crawled sex advertisements to assist investigators in the real world is an important social problem involving many technical challenges. This article will describe the problem of domain-specific search (DSS), a specific set of technologies that can address these challenges, drawing on cutting-edge techniques developed over three years of DARPA-funded research conducted in collaboratively academic (e.g., the University of Southern California's Information Sciences Institute), government (e.g., NASA's Jet Propulsion Laboratory), and industrial (e.g., Uncharted) settings to assist analysts and investigative experts in the HT domain. Specifically, the article will describe the background, main principles and challenges of building a DSS in illicit domains and the general architecture of a DSS designed for illicit sex advertisements on the open web. The article will conclude with the scope of future research in this area.