bluuebunny/crossref_metadata_2025 huggingface dataset:
FAKTOR RISIKO HIPERTENSI
Authors: Purnama Ria Sihombing Esther , Hidayat Wisnu , Sinaga Janno , Nababan Donal , Ester J. Sitorus Mido
Published: February 2024

Hipertensi masih menjadi bahaya kesehatan karena merupakan penyakit yang bersifat 'silent killer' Hipertensi dapat meningkatkan tekanan didalam pembuluh darah di atas normal dan menempatkan pasien pada risiko penyakit jantung, stroke, dan gagal ginjal. Faktor risiko Riwayat keluarga/keturunan, tingkat pendidikan, stress, kebiasaan minum kopi, kebiasaan merokok berhubungan dengan peningkatan risiko hipertensi Tujuan penelitian ini untuk mengetahui faktor risiko yang paling dominan mempengaruhi kejadian Hipertensi Masyarakat Usia Produktif Diatas Umur >40 Tahun di wilayah Kecamatan Nainggolan Periode 2021-2022. Penelitian ini merupakan penelitian analitik observasional dengan desain studi kasus-kontrol (case-control study). Responden dalam penelitian ini masyarakat usia > 40 tahun di wilayah kerja Puskesmas Sirait dengan jumlah kelompok kasus sebanyak 50 responden dan kelompok kontrol sebanyak 50 responden. Adapun analisis yang digunakan dalam penelitian ini adalah analisis univariat, bivariat, dan multivariat. Penelitian ini menggunakan  uji Chi –Square dan selanjutnya  menggunakan regresi logistik untuk melihat faktor yang paling berpengaruh. Hasil Uji Chi-Square menunjukkan ada hubungan Riwayat Keluarga/ keturunan hipertensi (p=0,002 OR=4,89 95%CI=1,76 - 13,69,) dan Kebiasaan merokok (p=0.047,  OR=1,54 95%CI=1,00 - 2,37)  terhadap kejadian hipertensi dan tidak ada hubungan  tingkat pendidikan responden (p=0,294 OR=0,727 95%CI=0,40 - 1,32), Tingkat stress (p=0.500 OR=1,36 %CI=0,55 - 3,29), kebiasaan Minum kopi(0.872 OR=0,95 95%CI=0,50 - 1,78) terhadap kejadian hipertensi faktor yang paling dominan adalah faktor keluarga/ keturunan (p=0.002) OR=5,246  95%CI=1.846-14.910 yang artinya responden dengan riwayat keluarga/keturunan mempunyai risiko terkena hipertensi 5,246 kali dibanding responden yang tidak memiliki riwayat keluarga/keturunan  Disarankan agar Puskesmas dapat membuat program pencegahan dan penurunan angka kejadian hipertensi melalui kegiatan Deteksi dini/Skrining ifaktor risiko penyakit hipertensi di setiap desa secara rutin setiap bulan serta melakukan edukasi tentang penyakit hipertensi dan faktor-faktor risiko terjadinya hipertensi iterutama pada masyarakat yang memiliki riwayat keluarga/keturunan. Hipertensi dan riwayat merokok.
HUBUNGAN STANDAR KOMPETENSI PERAWAT DENGAN REWARD YANG DIBERIKAN MANAJEMEN RSUD JAYAPURA
Authors: Simaremare Hizkia , Tua Siagian Mindo , Sinaga Taruli Rohana , Manurung Kesaktian , Lina Tarigan Frida
Published: February 2024

Perawat rumah sakit selalu menjadi ujung tombak dan berada di garda terdepan dalam memberikan pelayanan ketika pasien masuk ke rumah sakit. Tenaga kesehatan khususnya perawat Rumah Sakit yang mendapatkan reward yang layak akan berdampak pada kualitas pelayanan kesehatan secara khusus kepada pasien yang sedang rawat inap dan berobat jalan. Tujuan penelitian ini adalah untuk mengetahui hubungan antara standar Kompetensi Perawat dengan Reward yang diberikan Manajemen RSUD Jayapura. Penelitian ini menggunakan metode mixed methods research design di mana menggunakan 2 (dua) tahapan penelitian kegiatan yaitu pengumpulan data secara Kuantitatif dengan menggunakan analisis data  dan dengan pendekatan kualitatif melalui teknik wawancara langsung kepada beberapa perawat. Penelitian ini menghasilkan temuan bahwa tidak ada hubungan antara Standar Kompetensi Perawat dengan reward yang diberikan manajemen RSUD Jayapura dengan nilai (p Value = 0.553) dan ada hubungan antara masa kerja perawat dengan reward yang diberikan oleh Manajemen RSUD Jayapura dengan nilai (p Value = 0.021). Setelah melakukan wawancara mendalam, peneliti menemukan jenis-jenis reward yang diterima perawat diluar gaji bulanan antara lain, Jasa Medis berupa BPJS, KPS(Kartu Papua Sehat), dan Swasta. Kemudian peneliti juga menemukan fakta bahwa pemberian reward tidak hanya tergantung pada lamanya seorang perawat berkerja, namun juga status perawat (Perawat tetap atau tidak tetap) dimana sebagian besar yang sudah menjadi perawat tetap sudah berkerja cukup lama sebagai tenaga perawat. Lebih lanjut, berdasarkan informasi yang diperoleh dari perawat, peneliti menemukan bahwa pemberian reward seperti gaji dan jasa medis yang menjadi hak perawat sering mengalami keterlambatan pembayaran. Dengan adanya temuan ini maka diharapkan pihak Manajemen RSUD Jayapura terus meningkatkan kompetensi perawat terutama untuk lebih memperhatikan kesejahteraan semua tenaga kesehatan terutama perawat.
FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN KELUHAN COMPUTER VISION SYNDROME (CVS) PADA PENGGUNA KOMPUTER BAGIAN ADMINISTRASI DI PT EKAPUTRA PRADA INDONESIA TAHUN 2023
Authors: Olivia.H.R Elsha , Puteri Ade Dita , Isnaeni Lira Mufti Azzahri
Published: February 2024

Computer Vision Syndrome (CVS) merupakan sekelompok tanda dan gejala masalah mata yang terkait dengan pekerjaan jarak dekat yang di alami seseorang dan berlangsung selama atau setelah penggunaan komputer, telepon seluler, tablet, dll. Penelitian ini bertujuan untuk mengetahui hubungan usia, masa kerja dan lama penggunaan komputer pada pekerja pengguna komputer bagian administrasi di PT. Ekaputra Prada Indonesia Kota Pekanbaru. Penelitian ini merupakan penelitian kuantitatif analitik dengan desain cross sectional. Sampel dalam penelitian ini adalah semua pekerja pengguna komputer bagian administrasi PT. Ekaputra sebanyak 41 responden. Variabel dalam penelitian ini adalah usia, masa kerja, lama penggunaan komputer dan keluhan computer vision syndrome. Analisis data yang digunakan mencakup analisis univariat dan bivariat menggunakan uji Fisher’s Exact Test. Hasil penelitian didapatkan adalah tidak ada hubungan yang signifikan antara usia dengan keluhan CVS (p-value = 0,233 > 0,05), ada hubungan yang signifikan antara masa kerja dengan keluhan CVS (p-value = 0,007 < 0,05), ada hubungan yang signifikan antara lama penggunaan komputer dengan keluhan CVS (p-value = 0,000 < 0,05). Untuk mencegah keluhan CVS perusahaan PT. Ekaputra sebaiknya melakukan penyuluhan mengenai Computer Vision Syndrome, penyebab terjadinya CVS serta cara pencegahannya kepada seluruh karyawan yang bekerja dengan menggunakan komputer agar karyawan dapat menerapkannya saat bekerja. Disamping itu perlu tindakan pemeriksaan kesehatan rutin secara berkala untuk mengetahui kondisi mata ada atau tidaknya gangguan kesehatan mata pada karyawan.
GAMBARAN KEPUASAN PASIEN TERHADAP LAYANAN DAN KUALITAS MAKANAN DI RUMAH SAKIT: LITERATURE REVIEW
Authors: Alie Nuzul Shafira , Syamsu Rachmat Faisal , Dahlia Dahlia
Published: February 2024

Rumah Sakit adalah fasilitas kesehatan yang sangat penting bagi masyarakat. Dalam struktur organisasi Rumah Sakit, pelayanan gizi adalah pelayanan penunjang medis yang dikelola oleh Instalasi Gizi. Tingkat kepuasan pasien terhadap kualitas layanan gizi sangat memengaruhi reputasi Rumah Sakit dan loyalitas pasien juga diduga dipengaruhi oleh standar pelayanan makanan. Tujuan dari tinjauan literatur ini adalah untuk mengetahui gambaran kepuasan pasien terhadap pelayanan dan kualitas makanan di Rumah Sakit. Menggunakan metode literature review dengan prinsip Diagram Alir PRISMA. Artikel atau jurnal ilmiah diunduh dari PubMed, Portal Garuda, dan Google Scholar dengan standar SINTA IV dan V. Kata kunci dalam pencarian artikel ini yaitu pelayanan makanan di Rumah Sakit, kualitas makanan dan kepuasan pasien terhadap pelayanan dan kualitas makanan di Rumah Sakit. Didapatkan 120 artikel dalam hasil pencarian. Semua artikel diseleksi berdasarkan kriteria inklusi diperoleh 16 artikel penelitian yang akan di telaah. Hasil penelitian menunjukkan bahwa kepuasan pasien terhadap pelayanan makanan di Rumah Sakit dipengaruhi oleh kualitas makanan (rasa, tekstur, penampilan, variasi, dan kebersihan) dan kualitas pelayanan makanan (sistem, peralatan makan, sikap staf, dan kinerja). Kepuasan pasien dipengaruhi oleh makanan dan kualitas pelayanan makanan sehingga diperlukan evaluasi secara terus-menerus.
FAKTOR YANG BERHUBUNGAN DENGAN PERSONAL HYGIENE PEDAGANG MAKANAN JAJANAN DI PASAR TRADISIONAL SURAKARTA
Authors: Wulandari Windi , Rahayu Alfinna Setya , Sari Amalia Anita
Published: February 2024

Makanan jajanan merupakan makanan yang penyajiannya dalam wadah atau sarana penjualan di tempat-tempat umum seperti penjual pinggir jalan, pasar tradisional atau tempat lain yang sudah dipersiapkan atau diolah ditempat produksi/rumah/tempat berjualan. Makanan jajanan berpotensi menjadi media penularan penyakit apabila penjamah makanan tidak memperhatikan personal hygiene. Personal hygiene pedagang jajanan pasar yang kurang diperhatikan dapat menyebabkan terjadinya penularan penyakit bawaan makanan. Tujuan dari penelitian ini untuk mengetahui faktor yang berhubungan dengan personal hygiene pedagang makanan jajanan di Pasar Tradisional Surakarta. Jenis penelitian adalah penelitian kuantitatif dengan pendekatan observasional analitik. Desain penelitian ini menggunakan cross sectional. Tempat penelitian di enam pasar tradisional Surakarta yaitu Pasar Nusukan, Pasar Nangka, Pasar Kleco, Pasar Gede, Pasar Harjodaksino, dan Pasar Kadipolo. Sampel penelitian ini adalah pedagang makanan jajanan yang berjumlah 52 pedagang. Analisis data yang digunakan dalam penelitian ini meliputi analisi univariat dan bivariat. Uji analisis data menggunakan uji Chi Square. Hasil penelitian menunjukkan bahwa ada hubungan antara pengetahuan nilai p value 0,048 dengan personal hygiene pedagang makanan jajanan. Tidak ada hubungan antara pendidikan nilai p value 0,299 dan fasilitas sanitasi nilai p value 0,710 dengan personal hygiene pedagang makanan jajanan. pedagang makanan jajanan di pasar tradisional Surakarta tetap menjaga personal hygiene dan fasilitas sanitasi agar mutu makanan jajanan terjaga dan tidak menimbulkan masalah kesehatan
Charisma and learning: designing charismatic behaviours for virtual human tutors
Authors: Lakeisha Onyango  , Rahma Ahmed Darwesh  , Precious Jadini  , Uthaynah Abdullatif
Published: February 2024

Charisma as defined in the Oxford Dictionary, is the compelling attractiveness or charm that can inspire devotion in others. It is a powerful device of communication because it is the primary way humans signal interpersonal closeness, willingness to communicate, and feelings toward one another. Without exception, charisma is very crucial in the learning process in individuals. It makes the teachers more influential, causing learners to listen more intently to what they have to say and subsequently boosting their learning performance at the end of the day.
Virtual learning has become a widely adopted phenomenon all around the world, with the aid of virtual humans (computer-generated simulations of human beings), who, unlike real humans, provide consistency in the delivery of accurate knowledge, engaging role-plays, and appropriate feedback. Furthermore, pedagogical agents have played a significant role in virtual learning, and virtual tutors and companions falling under this category. Incorporating charismatic behaviors in virtual human tutors has become a quest for developers, due to their awareness on how impactful it can be in virtual learning. How can such behaviors be realized in a virtual character? Developers are incorporating charismatic traits in virtual human tutors which include: portraying a high degree of engagement with their students, proficiency in their subject matter, organized and very profound in their knowledge of the subject. Taiwanese authors researched the topic of teaching and charisma. The Statistical results obtained supported the virtual human tutors’ charisma has a positive influence on inducing the students’ learning interest.
Feelings of isolation that may be faced by a student in online learning are overcome by the fully-present and approachable trait of the charismatic virtual tutor. The ability of a virtual human tutor to be charismatic boosts instructor immediacy; behavior that brings the instructor and the students closer together in terms of perceived distance.
Overall, we conclude that developers’ endeavor to design charismatic behavior for virtual human tutors is advantageous to the highly advancing educational field and the use of Artificial Intelligence in education.
An examination of jealousy and relationship satisfaction in romantic relationships
Authors: Çulfa Ekrem , Izgi Ferah Diba
Published: February 2024

This study has been conducted to examine the relation between attachment styles, romantic jealousy and relationship satisfaction. Moreover, how these mentioned variables differ in terms of sex and relationship types is also explained. Study group of this study consist of totally 500 participants, 250 males and 250 female participants, who live within İstanbul Metropolitan Municipality district. Personal Information Form, Romantic Jealousy Scale, The Experiences in Close Relationship Scale-II, Relationship Satisfaction Sub-Scale of Relationship Stability Scale have been used as data collection tools in this study.
Results of analysis show that there is a positive correlation between relationship satisfaction and romantic jealousy. Results show that attachment styles are considerable predictors of romantic jealousy level; that jealousy increases as anxious attachment increases; that jealousy decreases as avoidant attachment increases; and also that there is a weak positive relation between avoidance and anxiety dimensions of attachment. Moreover, there has been a negative relation between avoidant attachment and relationship satisfaction. Findings show that sex and relationship type have significant roles in jealousy, that women are more jealous than men, especially those who are flirting are more jealous than those who are married. It has been seen that relationship type is effective in attachment and those who are flirting are more anxiously attached than those who are married.
Drug Resistance in Hepatocellular Carcinoma: Theoretical Basis and Therapeutic Aspects
Authors: Lei Ya-ruo , He Xian-lu , Li Jun , Mo Chun-fen
Published: February 2024

Primary liver cancer is one of the most common malignant tumors with high mortality and increasing incidence worldwide. Currently, chemotherapy is an important comprehensive treatment for moderate or advanced liver cancer. Despite the effective therapeutic effects initially achieved by chemotherapy, the high phenotypic and molecular heterogeneity of liver cancer cells facilitates resistance to conventional chemotherapy or targeted therapy and even leads to multidrug resistance (MDR), which is one of the major obstacles for clinical chemotherapy. Drug resistance exhibits multiple and complex molecular mechanisms to antagonize therapy under pharmacological pressure, including overexpression of drug efflux transporters, downstream adaptive response (such as apoptosis, autophagy, and endoplasmic reticulum stress), dysfunction of DNA damage repair (DDR), epigenetic modification, tumor microenvironment (TME) as well as extracellular matrix (ECM). In this paper, we summarize the recent research progress and intervention strategies for drug resistance in hepatocellular carcinoma (HCC), which will provide a promising therapeutic strategy for overcoming MDR in liver cancer.
Bivalent Hemagglutinin Cleavage-Site Peptide Vaccines Protect Chickens from Lethal Infections with Highly Pathogenic H5N1 and H5N6 Avian Influenza Viruses
Authors: Chowdhury Dibakar , Lin Xiao Han , Seo Sang Heui
Published: February 2024

Background: Outbreaks of highly pathogenic avian influenza viruses cause huge economic losses to the poultry industry worldwide. Vaccines that can protect chickens from infections caused by various variants of highly pathogenic H5Nx avian influenza viruses are needed owing to the continuous emergence of new variants. We previously showed that vaccines containing the H5 cleavage-site peptide from clade 2.3.4.4. H5N6 avian influenza virus protects chickens from infection with homologous clade 2.3.4.4. H5N6 avian influenza virus, but not from infection with the heterologous clade 1 H5N1 avian influenza virus. Therefore, we developed bivalent peptide vaccines containing H5 cleavage sites of viruses from both clades to protect chickens from both H5N1 and H5N6 avian influenza viruses. Methods: Chickens were vaccinated with two doses of a combined peptide vaccine containing cleavage-site peptides from clade 1 and clade 2.3.4.4. highly pathogenic H5N1 and H5N6 avian influenza viruses and then challenged with both viruses. The infected chickens were monitored for survival and their tracheae and cloacae were sampled to check for viral shedding based on the median tissue culture infectious dose of 50 (log10TCID50/mL) in Madin–Darby canine kidney cells. Results: Antibody production was induced at similar levels in the sera of chickens immunized with two doses of the combined peptide vaccines containing cleavage-site peptides from highly pathogenic H5N1 and H5N6 avian influenza viruses. The immunized chickens were protected from infection with both H5N1 and H5N6 avian influenza viruses without viral shedding in the tracheae and cloacae. Conclusions: Dual-peptide vaccines containing cleavage-site peptides of both clades can protect chickens from highly pathogenic avian influenza virus infections.
impacto de las malas noticias en las enfermedades neurológicas: el reto en la comunicación médico-paciente
Authors: Trujillo de los Santos Zoila , Paz Rodríguez Francisco , Sánchez Guzmán María Alejandra
Published: February 2024

Objetivo: En el contexto de las enfermedades neurológicas con frecuencia se comunican malas noticias. Describimos la forma en que se dan/reciben malas noticias en la relación médico-paciente. 
Material y Método: Estudio transversal descriptivo mediante encuesta, participaron 50 neurólogos y 145 pacientes con enfermedad neurológica. Se elaboró un cuestionario Ad hoc, para valorar la comunicación/recepción de malas noticias.  
Resultados: Únicamente 11% de los médicos siempre las informan. Respecto a la formación, el 56% aprendió viendo a otros especialistas. Para los pacientes, la notificación del diagnóstico es la “mala noticia" más frecuente (53.4%). Tanto los neurólogos como los pacientes reportan que el modo de comunicación fue verbal 85.5% y 36.0% respectivamente. En la expresión emocional, el 52% de los médicos señalaron que permiten al paciente expresarse, solo el 4.8% de los pacientes dijeron que pudieron expresar su emoción.
Conclusión: Los médicos no reciben capacitación en el tema. Estos resultados sugieren que deben hacerse adecuaciones en la formación de los neurólogos, que incluya herramientas que favorezcan la comunicación dialógica.
Prospective analysis of a TRD cohort over a 1-year follow-up with standard of care in Mexico: results for depression severity, treatment response, disability and QoL from the multicenter, observational TRAL Study
Authors: Zambrano Javier , Vázquez Hernández Juan Luis , Brandi Rigal Francisco Fernando , Alviso de la Serna Luis Daniel , Kanevsky Gabriela , Perocco Sergio
Published: February 2024

Introduction: Based on TRAL Mexico subsample, clinical outcomes and Patient-Reported Outcomes (PROs) are reported here. Methods: From 697 patients with MDD recruited from 14 Mexican sites, 140 patients with diagnosis of TRD under standard of care (SOC) were included in the 1-year follow-up. Patients with relevant psychiatric comorbidities or active participation in a clinical trial were excluded. Outcomes were obtained from PROs and clinical assessment scales. Results: Patients were mostly female (82.6%), with a mean age of 47.6 years. Only 44.3% of the patients achieved a clinical response, and remission was around 37% (measured through MADRS). Results from PHQ-9, EQ-5D and SDS show significant symptoms and disability for TRD patients in their everyday life after 1-year of follow-up with SOC. Discussion: TRD patients showed a significant burden of the disease, as current SOC fails to deliver clinically meaningful results for the majority of the patients. Response, remission and relapse are far from the desired outcomes Conclusion: Mexico has undertaken relevant and meaningful strategies to improve mental health resources availability, but some unmet needs are yet to be addressed. All involved stakeholders should consider public policies to enhance clinical outcomes and availability of resources.
Inter-rater Reliability of the DSM-5 and ICD-11 Criterion A for PTSD and Complex PTSD in Parents of Autistic Children using the Life Events Checklist
Authors: Hinde Kylie , Hald Gert Martin , Hallford David John , Lange Theis , Arendt Mikkel Christoffer Berg B , Pavan Silvia , Austin David W.
Published: February 2024

Parents of autistic children demonstrate elevated traumatic stress symptoms, but seldom receive diagnoses of post-traumatic stress disorder (PTSD) or complex-PTSD. An accurate assessment of Criterion A is essential for a valid diagnosis of these disorders, yet it is uncertain whether Criterion A, as defined by the two primary international diagnostic systems (Diagnostic and Statistical Manual of Mental Disorders, fifth edition – text revision [DSM-5-TR] and International Classification of Diseases, 11th edition [ICD-11]), yields consistent inter-rater reliability (IRR), when psychologists rely solely on self-report from these parents for assessing PTSD or complex-PTSD. Ten Australian psychologists independently rated parents’ self-reported traumatic events related to parenting, using the Life Events Checklist for Criterion A according to the DSM-5-TR and ICD-11. 200 parents of autistic children were randomly selected from a larger dataset, all meeting symptom thresholds for either PTSD or complex-PTSD related to their self-reported parenting-related trauma. Bootstrapping was used to calculate kappa coefficients and differences between ICD-11 and DSM-5-TR criteria, and self-reports of threat or no threat, by subtracting kappa values and calculating 95% confidence intervals for these differences. Inter-rater reliability (IRR) varied from poor to moderate. ICD-11 had significantly higher reliability than DSM-5-TR for Criterion A (diff = 0.105, 95% CI [0.052, 0.153], p<.001). IRR was lower when parents reported life-threat, serious injury, or death (diff =0.096, 95% CI [0.019, 0.176], p=.007). This study highlights challenges in assessing PTSD and Complex-PTSD Criterion A in parents of autistic children using DSM-5-TR and ICD-11 criteria with the LEC-5, revealing less than adequate IRR.
Time for transparent targeting: an investigation of targeting disclosures, coping mechanisms, credibility, and political attitude
Authors: Jansen Martin , Meier Yannic , Krämer Nicole
Published: February 2024

A major problem with political microtargeting (PMT) is that users are often unaware that they are being targeted, whereas current transparency approaches fail to inform users. Therefore, the current work investigates two types of disclosures on a political advertisement, one that is currently used by platforms: a light gray sentence stating that content is sponsored, and a salient and dynamic disclosure that informs users about the parameters and data points used to target them. This work investigates whether these disclosures, as a means of transparency to counter the potential negative effects of PMT, affect users in terms of persuasion knowledge, resistance, source credibility, and attitude towards the advertised politician. In a preregistered online one-factorial between-subjects experiment (N = 547), we found no evidence for the claim that a more elaborate, salient targeting disclosure increases users’ persuasion knowledge. However, our results show that persuasion knowledge is related to cognitive resistance, which, in turn, is related to both source credibility and users’ attitude towards the advertised politician. Our results further indicate that this process is cognitive, rather than affective. Finally, most participants seemed to recall a disclosure, although it was not always the correct one.
Pooled breast cancer gene expression dataset with detailed treatment regimen characterization
Authors: Jose Vinu , Venet David , Buisseret Laurence , Rothe Francoise , Sotiriou Christos
Published: February 2024

Pre-clinical studies reported the immunogenic or immunomodulatory effects of traditional cancer therapies. However, the publicly available well-curated and harmonized breast cancer datasets, such as TCGA, METABRIC, and MetaGxBreast, lack careful curation of treatment regimens. Hence, limited exploration of the impact of therapies on the prognostic/predictive value of breast cancer biomarkers. Herein, we describe a pooled and treatment-curated gene-expression dataset to investigate the impact of treatments on the prognostic/predictive value of biomarkers. We searched the gene expression omnibus database repository to identify potential human breast cancer gene-expression datasets with treatment details. Published datasets with detailed treatment regimen, clinical endpoint, clinical-pathological, and gene-expression data were extracted and harmonized. The dataset described herein would help researchers explore the interaction between gene-expression biomarkers and immunogenic/immunomodulatory treatments in breast cancer.
Toward a second-person approach to investigating schizophrenia: (mis)perceiving others in the perceptual crossing experiment?
Authors: Zapata-Fonseca Leonardo , Belhadi Aisha , Leenen Iwin , Sangati Federico , Fossion Ruben , Fuchs Thomas , Froese Tom
Published: February 2024

Though negative symptoms and social difficulties are significant sources of disability in patients with schizophrenia, they are poorly studied compared to delusions and hallucinations. In parallel, there are calls for a shift in our understanding of psychiatric diseases, towards viewing them as disorders of social interaction. We argue that an embodied and enactive approach might be well-suited to address this gap, and that one way to operationalize this approach is with the Perceptual Crossing Experiment (PCE) in patients with schizophrenia. In the PCE, two participants are supposed to find each other in a virtual space that also contains other objects, using a minimal haptic interface and relying on the interactive dynamic patterns. We present a small pilot study with seven schizophrenia patients, each of whom interacts with a control participant. The outcomes show trends towards low levels of interaction with all objects and low overall number of responses (“clicks”) for both types of participants, possible differences between patients and controls on the type of object they misidentify as their partner, and for both participants, higher subjective ratings of a collective experience when both participants clicked, even in the absence of joint recognition. These preliminary findings urge us to redefine our hypotheses in social psychiatry and the PCE, bringing to the fore the importance of uncertainty, error, and overall dyadic dynamics. Studying these concepts through the PCE has the potential of linking the phenomenological understanding of schizophrenia as a disorder of disembodied interaction with an understanding of its neurocomputational basis.
How funny is ChatGPT? A comparison of human- and A.I.-produced jokes
Authors: Gorenz Drew , Schwarz Norbert
Published: February 2024

Can a large language model produce humor? Past research has focused on finding examples of these models succeeding or failing at producing humor in the eyes of the authors, without surveying peoples’ actual judgments of its output. These examples, while interesting, do not shed light on exactly how funny ChatGPT is to the general public, nor do they analyze ChatGPT’s humor production abilities in comparison to humans’ abilities. To explore this question, we gave the same comedic prompts to ChatGPT 3.5 and laypeople, and asked them to generate humorous responses (Study 1). We also asked ChatGPT 3.5 to generate humorous satirical headlines and compared them to published examples from professional comedy writers at The Onion (Study 2). Other participants rated the funniness of the human and A.I.-produced responses in each study. ChatGPT 3.5-produced jokes were rated as equally funny or funnier than human-generated responses regardless of the comedic task and the expertise of the human comedy writer.
Highly invariant recognition memory spaces for real-world objects revealed with signal-detection analysis
Authors: Utochkin Igor , Azarov Daniil , Grigorev Daniil
Published: February 2024

Recognition memory is an essential form of memory retrieval, allowing us to determine whether a thing or episode we experience in the present has been experienced in the past. Recognition typically involves decisions on whether stimuli look "old" or "new". These decisions can be difficult, especially when the new stimuli are similar to the old ones (e.g., as in police lineup identification). Although the role of similarity between old (targets) and new (foils) in recognition is obvious, it is often hard to predict how confusable particular targets and foils would be and how much of their confusability comes from their similarity as opposed to insufficient memory. Here, we show that, even when stimuli are various real-world objects whose subjective similarity depends on numerous non-defined factors and varies across people, they form highly consistent recognition memory spaces. That is, proportions of correct (hits) and incorrect recognitions (false alarms) produced by certain target-foil combinations are distributed similarly across different participants. Moreover, using the discriminability index d' from signal-detection theory as a distance metric, we found that the recognition spaces recovered from simple two-alternative choice tests (2-AFC) correctly predicted performance in more complex 4-AFC tests not only for hits but differentiated false alarms for each foil. We also found that the decreased encoding time reduced all absolute d' distances (presumably due to lower memory strength) but preserved the relative distances. Therefore, we found evidence for highly consistent signal-detection recognition memory spaces of real-world objects invariant to memory task complexity.
Too Hard, Too Easy, Or Just Right? The Effects of Context on Effort and Boredom Aversion
Authors: Embrey Jake Ryan , Mason Alice , Newell Ben R
Published: February 2024

Despite people’s general desire to avoid cognitive effort there is a limit to our parsimony: boredom, a state defined by a lack of mental engagement, is found similarly aversive. The work presented here investigates how context—the alternative tasks present and the environmental context—impacts people’s aversion to exerting cognitive effort and avoiding boredom via a demand-selection task. In a population of undergraduate students, we assessed how people’s willingness to exert mental effort (in a working memory task) is affected by the presence of an easier alternative (less cognitively demanding) or a boring alternative (doing nothing at all). To manipulate environmental context, we conducted the experiment both online, where participants complete the task remotely, and in a controlled laboratory setting. We find people willingly seek out effortful tasks to avoid boredom, despite avoiding high demands when both tasks on offer required some effort. We also find large effects of the participants’ environmental context, with preferences for the most demanding task increasing by over 150% in the lab compared to online. These results bear relevance to theories which argue the costs of effort are determined relative to the alternatives available (e.g., opportunity cost theories). Moreover, the results demonstrate that researchers who deliberately (or inadvertently) manipulate effort and boredom must consider the effects context (both choice and environmental) has on people’s behaviour.
Effects of causal structure and evidential impact on probabilistic reasoning
Authors: Konuk Can , Navarre Nicolas , Mascarenhas Salvador
Published: February 2024

We compare two perspectives on base-rate neglect (Kahneman & Tversky, 1973) in probabilistic judgment. The evidential impact perspective derives it from humans’ focus on the impact of evidence on belief, rather than conditional probabilities. The Causal Models perspective derives it from humans’ inability to integrate information that is causally opaque, as base-rates often are in such experiments. Because causal and evidential-impact relations are often concomitant and confounded, we designed an experiment that specifically teases apart their respective influence on probabilistic judgment. Our results support a combination of the two perspectives, with causal transparency influencing the degree to which one engages in evidential impact reasoning strategies.
DUKUNGAN ORANG TUA, EFIKASI DIRI BELAJAR SECARA DARING, DAN BURNOUT AKADEMIK PADA SISWA SMA SELAMA COVID-19
Authors: Azkarisa Yang D. , Nugraha Sumedi P
Published: February 2024

Penelitian ini bertujuan untuk mengetahui peranan efikasi diri dan dukungan orang tua dalam menjelaskan burnout akademik pada siswa SMA selama pandemi COVID-19. Penelitian ini melibatkan 227 siswa SMA N 1 Lingga yang menjalani pembelajaran daring. Data dikumpulkan secara online dengan menggunakan tiga skala pengukuran yaitu Maslach Burnout Inventory-Students Scale (MBI-SS), General Self Efficacy (GSE) dan Social Support Questionnaire for Children (SSQC). Teknik analisis menggunakan analisis regresi ganda. Hasilnya menunjukkan bahwa efikasi belajar secara daring dan dukungan orang tua mampu memprediksi burnout akademik pada siswa SMA N 1 Lingga selama pembelajaran daring (F= 27.523, p < 0.001).
Metode Vulnerability Assesment Dalam Pengujian Kinerja Sistem Keamanan Website Points of Sales
Authors: Wahyudin Wahyudin , Kuswara Heri , Resti Resti , Dalis Sopiyan
Published: February 2024

Perkembangan perdagangan elektronik melalui website berbasis point of sales terkait erat dengan tingkat pertumbuhan internet, karena perdagangan elektronik berjalan melalui jaringan dan koneksi Internet. Namun, semakin banyaknya website berbasis point of sale yang dibangun, semakin besar pula kemungkinan terjadinya serangan cyber yang dapat merugikan website tersebut. Oleh karena itu, keamanan website menjadi sangat penting untuk diperhatikan. Salah satu metode yang dapat dilakukan untuk menjaga keamanan website adalah dengan melakukan Vulnerability Assessment. Vulnerability Assessment adalah sebuah proses pencarian celah keamanan pada sistem informasi atau jaringan computer dengan tujuan untuk mengidentifikasi potensi kerentanan keamanan dan mengambil langkah pencegahan sebelum serangan terjadi. Berdasarkan pengujian dengan tool Owasp ZAP, hasil dari scanning yang telah dilakukan pada website sakupos.com yang merupakan website berbasis points of sales bahwa terdapat kerentanan pada website tersebut. Hasil pengujian menunjukkan Level Kerentanan (Risk Assessment) serta Rekomendasi solusi yang bisa digunakan untuk mencegahnya. Terdapat ada 10 kerentanan yang terdeteksi, ditemukan 7 kerentanan dengan level/tingkat resiko Medium, 2 kerentanan dengan tingkat resiko Low, Serta 2 kerentanan lainnya di tingkat resiko Informational.
Review: Senyawa Fitokimia Daun Kunyit
Authors: Harmini Sri , Wibisana Dharend Lingga
Published: February 2024

Tanaman kunyit merupakan salah satu tanaman yang banyak dimanfaatkan karena memiliki efek yang baik bagi kesehatan manusia. Pemanfaatan kunyi terbatas pada rimpang kunyit. Bagian lain dari tanaman kunyit, antara lain adalah daun, belum banyak dimanfaatkan. Keberadaan daun kunyit sebagai limbah, dapat memberikan dampak yang kurang baik terhadap lingkungan. Jumlahnya yang cukup melimpah, dapat dimanfaatkan sebagai sumber senyawa fitokimia dan diaplikasikan pada industri makanan dan obat-obatan. Jurnal ini bertujuan untuk memberikan pemahaman terhadap manfaat daun kunyit ditinjau dari kandungan senyawanya, aktivitas antimikrobianya, minyak esensial yang dihasilkan dan pengaruh efek perlakuan terhadap kandungan senyawa fitokimianya. Hasilnya menunjukan bahwa daun kunyit memiliki aktivitas antimikrobia yang baik dengan adanya senyawa flavonoid dan tanin.
Optimizing Goods Claims Processing Time in Logistics Operations Through Website-Based Applications with the DMAIC Approach
Authors: Pratami Putri Monika , Kurnia Gita
Published: February 2024

PT XYZ is an e-commerce company which offers an electronic buying and selling platform for a wide variety of products from many sellers to buyers. As an industry engaged in the commercial sector, logistics has a vital role in shipping goods from upstream to downstream to meet consumer desires. However, conditions in the field are not always in accordance with the plans. Lost or damaged goods during delivery or at the Warehouse are a frequent problem. PT XYZ, through its XYZ Logistics team, implements a claims system for replacing items lost or damaged during the operational process. Currently, the claim submission system is done manually via email. This manual claim system creates many problems due to the lack of proper coordination between stakeholders. Therefore, this study proposed a solution with a lean six sigma approach using the DMAIC (Define, Measure, Analyze, Improve and Control) method. The solution offered to improve PT XYZ's claim system is to design an automated claim system using a website-based application. After implementing a website-based application to automate the XYZ logistics claim process, it was proved that the company was able to reduce lead time by up to 60% from initial conditions, up to 33% of stakeholder workload, and improve data security and real-time supervision.
Analysis of Coding Machine Purchase Decisions Using the Analytical Hierarchy Process (AHP) Method
Authors: Novrisal Dimas , Mahmudah Winni Fazriah
Published: February 2024

The increasing public awareness of taking medicines, especially during the COVID-19 pandemic, has made the pharmaceutical industry grow very rapidly. Therefore, the company is trying to increase its production, so it needs to add a coding machine. The choice of machine has a long-term impact because it will be used to assist the production process in the next few years, so it is necessary to use a method that is able to solve problems involving the consideration of company leaders, namely the Analytical Hierarchy Process (AHP) method. The order of priority of the coding machine selection criteria is the ability to print codes (33.6%), maintenance and repair costs (29.6%), the convenience of spare parts, solvents or make-up. and ink (16.2%), price (12.5%), and ease of use (8.1%). Based on the respondent's questionnaire, the order of the best alternative coding machines is Supplier A at 49.12%, Supplier B at 27.28%, and last Supplier C at 23.60%.
A NEW STAGE OF THE VERNADSKY STATE GEOLOGICAL MUSEUM DEVELOPMENT
Authors:   Vernadsky State Geological Museum RAS, Titova A.V. , Cherkasov S.V. ,   Vernadsky State Geological Museum RAS
Published: February 2024

Evolution of the Vernadsky State Geological Museum of Russian Academy of Sciences is being analyzed from the mineralogical cabinet of the Emperor Moscow University through educational body of the Moscow State Geological Prospecting Institute and academic museum of the Russian Academy of Sciences to the public popular scientific center in the field of Earth sciences and the embassy of the mining and geological industry in the society. A special attention is paid to the role of academician Yury Malyshev in the museum’s transformations.
RUSSIAN COAL INDUSTRY ON THE WAY OF REFORMS: YURY MALYSHEV IN “ROSUGOL” COMPANY
Authors:   self employed, Yanovsky A.B. , Kovalchuk , A.B. ,   COAL MARKETING RESEARCH INSTITUTE LTD, Rozhkov A.A. ,   Ministry of Energy RF, Skryl A.I. ,   Ministry of Energy RF
Published: February 2024

Yury Malyshev was the first and the only head of the state Rosugol enterprise (later – JSC) during the re-structuring of the coal industry. At the time, Yu.N. Malyshev demonstrated the highest level of responsibility, professionalism, unity of science and practice, experience, and young vigor, and the best human qualities in relation with colleagues an all the miners around the country.
GOLOGORSKY CHROMITE DEPOSIT AND ORE SAMPLES IN THE VERNADSKY STATE GEOLOGICAL MUSEUM OF RAS
Authors:   Vernadsky State Geological Museum RAS, Azarova Yu.V.
Published: February 2024

On the territory of Russia and, in particular, in the Urals, there are many deposits and mines that are now practically inaccessible for study. One of these is the Gologorsk chromite deposit, and the mine of the same name, created for the development of the deposit at the end of the 19th century (1864) and sunk in 1941. Gologorsk mine at the beginning of the 20th century was the largest and most equipped of all the chrome mines in the Urals. The mine accounted for about half of all chromite ore production in Russia, precisely at a time when the demand for chromite in the chemical industry was very high. In the collections of the Vernadsky State Geological Museum preserved two samples from this mine. This is almost solid chromite ore; the composition of the ore phase varies from aluminochromite to magnesiochromite. The results of studying the samples, as well as a brief history of the discovery and operation of this mine are presented in this article.
تعليمٌ يليق بالمستقبل
Authors: ميرسر رالف
Published: February 2024

تخيّل عالمًا يكون فيه التعليم أكثر من حفظ أصم واختبار موحَّد. عالمٌ يُشجَّع فيه الطلاب على استكشاف ترابط الأشياء جميعًا واعتناق مقاربةٍ للتعلّم أكثر شمولًا وأخلاقًا ومسؤوليّةً. وإنّها لتتّضح على نحو متزايد حقيقة أن نظامنا التعليمي لا يفي بالغرض ويحتاج لتغييرٍ جذري لمجاراة التقدّم التكنولوجي، والأزمة المناخية المتسارعة، ومتطلّبات استشراف المستقبليّات.
WORKSHOP PENULISAN KARYA ILMIAH BAGI GURU DI KECAMATAN KARANG JAYA MUSI RAWAS
Authors: Supriyanto Supriyanto , Isbandiyah Isbandiyah
Published: February 2024

Pengabdian pada masyarakat yang telah dilakukan ini adalah kegiatan workshop penulisan karya ilmiah bagi guru di Kecamatan Karang Jaya, Musi Rawas Utara. Kegiatan ini dilakukan sebagai upaya meningkatkan pemahaman dan keterampilan guru dalam menulis karya ilmiah seperti menulis makalah dan artikel ilmiah. Memiliki kemampuan dan keterampilan dalam bidang karya ilmiah merupakan tuntutan yang harus dipenuhi untuk kenaikan pangkat dan juga memenuhi komponen insturumen akreditasi agar sekolah mendapat skor maksimal, sehingga kegiatan workshop ini perlu dilakukan. Melalui kegiatan workshop ini diharapkan dapat membantu guru meningkatkan pemahaman dan keterampilan dalam menulis karya ilmiah dan membantu sekolah dalam meningkatkan akreditasi sekolah. Metode yang digunakan dalam kegiatan workshop penulisan karya ilmiah ini yaitu: 1) metode ceramah; 2) metode tanya jawab; dan 3) metode simulasi. Evaluasi kegiatan dilakukan selama proses dan akhir kegiatan, pada aspek pencapaian tujuan kegiatan dan juga penyelenggaraan kegiatan. Evaluasi proses dan hasil dilakukan dengan dokumentasi. Sedangkan evaluasi aspek penyelenggaraan kegiatan dilakukan dengan observasi. Indikator keberhasilan dalam pelaksanaan workshop penulisan karya ilmiah menggunakan 2 metode, yaitu: (1) evaluasi selama proses kegiatan, dan (2) evaluasi pasca kegiatan workshop.
Epidemiology of neuroendocrine tumors (NETs) and socio-clinical profile of patients according to data from the National Cancer Registry and the Federal Patient Registry of the MOLNEO Medical Society for Treatment of Neuroendocrine Tumor
Authors: Gorbounova Vera
Published: February 2024

It is well known that the incidence of NETs significantly exceeds the increase in the incidence of all other malignant tumors.
Investigating the Relationship between Cervical Erosion and Ectropion in Patients with Polycystic Ovary Syndrome and the Relationship with Estrogen Levels in Compared to the Control Group
Authors: Banouei Farshad
Published: February 2024

Introduction: Polycystic ovary syndrome is one of the most common diseases in society that one of its prominent features is the increase in blood estsrogen levels. This increase in estrogen levels in these patients is significantly associated with the occurrence of cervical lesions. In this study, we investigated the relationship between these disorders. Materials and methods: The present study is a prospective case-control study that was conducted between December 2021 and March 2023 on 200 patients that referred to the infertility clinic. The number of 200 patients was divided into 2 groups of 100 patients and 100 controls group, and the estrogen level and the presence of erosion and ectropion were measured in them, and the results were expressed by descriptive and analytical statistical methods. Results: In this study, estrogen levels in two groups of patients and controls were compared with each other and compared with the results of clinical examination in terms of the presence or absence of erosion, and a significant correlation was seen between estrogen levels in the two groups with the presence of erosion (P=0.006). There was no significant relationship between estrogen level and the presence or absence of ectropion (P=0.76). Discussion: The results of this study confirmed the existence of a significant relationship between the level of estrogen and the occurrence of erosion in patients, therefore, according to this, regular measurement of the level of estrogen in these patients and regular periodic examinations to prevent progression to malignancy seems to be necessary.
A Potantial Nesting Site for Loggerhead Turtle (Caretta caretta): Yakacık Beach, Türkiye
Authors: SÖZBİLEN Doğan
Published: February 2024

Monitoring of sea turtle nesting beaches in Türkiye have been conducted since 1988 and the number of beaches reached to 22. Mediterranean coast of Türkiye has many small pocket beaches and other inaccessible remote sandy beaches. In this study, I introduce a new nesting site, Yakacık Beach, for the loggerhead turtles (Caretta caretta) in the border of Antalya and Mersin provinces. Following the preliminary field studies on the 1.7 km long beach, 201 and 197 nests were found in 2020 and
2021, respectively, and the average nest density of the two years was calculated as 117.6 nests/km-1. Satellite images were also used to ensure and estimate the number of nests. The number of nest and the nest density were compared with the literature and Yakacık has the second highest nest density in Türkiye with a high predation rate up to 68%. The potential importance of Yakacık Beach and threats to the nesting beach and mitigation measures were discussed. Türkiye has one of the most important
nesting sites for the loggerhead turtles and the green sea turtles (Chelonia mydas) in the Mediterranean, with 17 nesting beaches identified in 1989. With the discovery of additional nesting sites such as Çıralı, Alata, Sugözü, Davultepe, and METUKocahasanlı beaches in the following years, the importance of Türkiye for sea turtle populations in the Mediterranean has gradually increased. With this study, a new nesting beach was identified and the importance of Türkiye for the Mediterranean Sea turtles was emphasized.
Institutional Pressures and Sustainable Business Practices: A Case of Strategic Environmental Management
Authors: Fatima Mahum , Ata Ghalib , Rizwan Aisha
Published: February 2024

Sustainability and environmental conservation have become key concerns for the developing and developed world, prompting firms to embrace sustainable business practices. The recent decade has witnessed a rise in environmental sustainability consciousness, with businesses and legislators incorporating environmental aspects into their strategic planning and practices. Strategic environmental management emphasizes the implementation of environmental management strategies through the incorporation of environmental concerns into business plans and decisions. This study proposes to investigate the isomorphic pressures that influence organizational behaviour and the significant determinants for addressing sustainable business practices. The qualitative research design is adopted and data is primarily collected through semi-structured interviews. The findings of this study from four significant service sectors highlighted various certifications, business requirements, corporate image and corporate social responsibility as the driving forces behind strategic environmental management. Legislations from government the appeared as the most influential factor to assume responsibility for the environment and society by the firms.