bluuebunny/crossref_metadata_2025 huggingface dataset:
Pulmonary Inflammatory Myofibroblastic Tumor in a Male Child; a Case Report
Authors: Seyedi Seyed Javad , Saeidinia Amin , Dehghanian Parisa
Published: April 2022

Pulmonary inflammatory myo-fibroblastic tumor (IMT) is a rare condition
in normal population and specifically in pediatric population. We
reported a 9-year-old male child presented by cough and intermittent
fever and weight-loss that was mostly suggestive for infectious process.
We reviewed the consideration of diagnosis and treatment and other
previous cases.
Elexacaftor-Tezacaftor-Ivacaftor improves exercise capacity in adolescents with cystic fibrosis
Authors: Causer Adam J. , Shute Jan , Cummings Michael , Shepherd Anthony , Wallbanks Samuel , Pulsford Richard , Bright Victoria , Connett Gary , Saynor Zoe
Published: April 2022

This study investigated whether Elexacaftor-Tezacaftor-Ivacaftor
(Kaftrio ), a cystic fibrosis (CF) transmembrane
conductance regulator (CFTR) modulator, could improve exercise capacity
in adolescents with CF. After six weeks treatment, Kaftrio
improved both maximal and submaximal indices of
aerobic fitness. Improvements were independent of changes in ventilatory
function during exercise and physical activity. Interestingly, pulmonary
oxygen uptake per unit of power output was higher in two, out of three,
cases who presented with more severe CF lung disease. These findings
suggest improved O extraction and/or consumption in
the exercising muscle and demonstrate, for the first time, that
short-term treatment with Kaftrio might improve
aerobic fitness in people with CF, especially in those with more severe
lung disease and deconditioning.
Prioritizing IT Management Issues and Business Performance
Authors: Klaus J. Philipp , Kim Kevin , Masli Adi , Guerra Katia , Kappelman Leon
Published: April 2022

We use a novel dataset extracted from the Society of Information Management's (SIM) survey of chief information officers (CIOs) and top information technology (IT) executives to examine organizations' most critical IT management issues during 2014–2017 and their effect on firm profitability. According to the SIM surveys, the top two IT issues management prioritizes are security/cybersecurity/privacy and IT alignment with the business. We find that firms that prioritize these two IT management issues exhibit higher profitability than firms that do not. Our study contributes to the Information Systems (IS) and Accounting Information Systems (AIS) literature on IT business value by providing empirical evidence on IT-business alignment—and to some extent IT security—positively affecting firm financial performance.
Effect of Nitrogen, Phosphorus and Sulfur Nutrients on Growth and Yield Attributes of Bread Wheat
Authors: Duga Rut
Published: April 2022

Wheat is one of the most important cereals cultivated in Ethiopia. The production and productivity of bread wheat are mainly constrained by the removal of soil nutrients from the soil, application of unbalanced fertilizer treatments and traditional farm management practices. Soil is one of the most important natural resources and medium for plant growth. It is a major source of nutrients needed by plants for growth. The objective of this review was design to pay attention to guide the effect and deficiency of Nitrogen, Phosphorus and Sulfur nutrients in plant growth of bread wheat. Nutrients are the essential components influence proper growth, development and quality of plants just like all other living organisms. Nitrogen is highly valuable plant nutrient and it is found in all plant cells, in plant proteins and hormones, and in chlorophyll. Phosphorous is an essential component of major cell proteins and nucleotides that are mainly responsible for development of different plant structures and helps transfer energy from sunlight to plants, stimulates early root and plant growth, and activate the maturity period. Sulfur is a ingredient of amino acids in plant proteins and is involved in energy-producing processes in plants and responsible for many flavor and odor compounds in plants. The deficiency and unbalanced application of nutrients are highly affected the growth, yield and quality of bread wheat. The use of right amount of fertilizer application based on crop requirement has a significant result for sustainable crop production.
Improving Decentralised Forest Governance Through Polycentric Systems: A Case Study of Kenya's Community Forest Management
Authors: Joseph Puthenkalam John
Published: April 2022

Community-Based Forest Management is a tool for local participation in forest management. Community involvement and stakeholder participation became important components of development and natural resource management, prompting developing countries to undertake decentralisation reforms by the 1990s. The reforms aimed to encourage participatory development, local empowerment and poverty reduction, democratisation, and resource sustainability. Their performance has, however, been mixed. Decentralisation efforts have suffered in situations where powerful actors, through various strategies, have managed to retain control over natural resources, obstructing power transfers to the communities. This has resulted in Responsibilisation, which is the transfer of responsibility to local communities without the transfer of requisite power. Responsive, collaborative governance is crucial in efforts to avoid responsibilisation. This refers to governance that devolves responsibilities and powers together, providing the requisite capabilities and support, enabling appropriate management decisions and actions at the devolved levels. Polycentric governance is crucial towards this end. Participatory Forest Management, a modality of Community-Based Forest Management, has been practised in Kenya since the Forest Act of 2005. This paper looks at forest polycentric governance institutional structures with cross-level interactions and representation bodies at each level of forest governance for successful social and ecological outcomes. This paper's product is a proposed forest polycentric governance institutional structure for better social and ecological outcomes in Kenya, which can be generalised to broader cases.
Shortage and Malnutrition Crisis in the Face of Covid-19 Pandemic Confinement in Africa: the Nigerian Narrative
Authors: NN Joe-Ikechebelu
Published: April 2022

With 21.7 million Nigerians unemployed, 7 million estimated poor and a probable poverty rise of 42.5% in 2020, the outbreak of the pandemic in Nigeria came at the worst era in the nation’s history. The COVID-19 pandemic and confinement, the continued neglect in modernizing the African agricultural sector, and its consequences on food insecurity, worsened an already existing crisis of food shortages with grim possibilities of malnutrition, as well as deepened health-related social inequities in Africa and in Nigeria. These inequities were exacerbated by the heavy dependence of the sub-Saharan African/Nigerian economy on non-agricultural sources. This paper was borne based on the grievances experienced in Africa and Nigeria, over food insecurity during COVID-19. The goal of this paper is to review food shortage and malnutrition crisis during the COVID-19 confinement in Africa with focus on Nigeria. This paper employed a secondary source of data collection and a descriptive approach. Findings showed that prior to the spread of the COVID-19 virus, the Nigerian agricultural sector has been surrounded by a plethora of problems limiting its productivity levels especially at the community level. Moreover, the spread of the COVID-19 virus in Nigeria with the mandatory 3 months confinement brought all socio-economic, government and private activities to a halt. This led to rapid income decline resulting in diminished sale of food products, rise of food prices, rapid purchase, hoarding of foodstuffs, hunger crisis, malnutrition, thereby worsening existing inequalities. This paper recommended best practices that would transform the Nigeria agricultural production and malnutrition challenges beyond the pandemic.
Impact of Climate Change on Forests in Cambodia
Authors: Kim Soben
Published: April 2022

Cambodia is rich in forest resources, which play critical roles in local rural livelihoods, as well as providing valuable ecological and economic resources for the country’s economic development. Managing forests sustainably and equitably will be essential for maintaining the ecological integrity of the country, maintaining freshwater supplies and protecting biodiversity. Approximately 80% of the Cambodians live in rural areas depend upon the forests to support many people’s lives as a source of food, medicine and building products, and as a source of materials and goods for small business ventures. Forest degradation globally contributes around 17 % to Green House Gases (GHG) emissions, but in Cambodia represents the main factor in the country becoming a net emitter of GHGs. Climate change is one of the most environmental issues facing to the government. The study aimed at i) assessing the impact of climate change on NPP, Vegetation Carbon and Soil Organic Carbon using LPJ model; ii) projecting the spatial representation of Impact of climate change on NPP, Vegetation Carbon stocks, and Soil Organic Carbon. The Lund Potsdam Jena (LPJ) model combines process-based, large-scale representations of terrestrial vegetation dynamics and land-atmosphere carbon and water exchanges in a modular framework. The model climate data requirements are benign as it requires only Temperature, Rainfall and Cloudiness as climatology inputs. Model validation is used for Net Primary Productivity (NPP), Vegetation Carbon (VegC), and Soil Organic Carbon (SoC). Obtaining observation of NPP, VegC, and SoC data for the region from the published literature or from the international databases and compare these with the LPJ projections (Spatially or non- spatially). As results, LPJ Simulated distribution on NPP in Cambodia using different scenarios including Baseline, RCP 8.5, and RCP 8.5 with control CO2 generated based on NPP, VegC, and SoC. Also, LPJ simulated Soil carbon change (%) projections for Cambodia under the RCP 8.5 under the two scenarios of CO2 fertilization and no-CO2 fertilization.
Post Cyclone Idai Evaluation of the Integrated Management of Acute Malnutrition (IMAM) Programme for Children under Five in Chimanimani, Zimbabwe
Authors: Mutonhodza Beaula
Published: April 2022

Background: Natural disasters like cyclones have been shown to cause food insecurity and infectious diseases leading to malnutrition. Objective: To evaluate the point prevalence of severe acute malnutrition (SAM) and moderate acute malnutrition (MAM) and post cyclone Idai Integrated Management of Acute Malnutrition (IMAM) response in Chimanimani district. Methods: A stratified random sampling method was used to select mother/child pairs who were IMAM beneficiaries. Clinic level records and reports on admissions and treatment outcome statistics were collected. Stories of most significant change (MSC), Focus Group Discussions (FDG) and Key Informants interviews were conducted. Results: At baseline, 74 children were admitted as malnourished, 25 had SAM and 49 had MAM, the number reduced to 45 with 13 SAM and 32 MAM four months post cyclone. The impact of the intervention was measured by the quality of treatment outcomes. The average cure rate from April to December for MAM was 79%, defaulter rate 19%, non-recovery 0%, died 2% and for SAM, cure rate 82%, defaulter rate 13%, died 0% and non-recovery 5%. The cure rate, non-recovery rate and death rate were in line with the SPHERE minimum standards Conclusion: The prevalence of SAM and MAM were highest two months after the cyclone with a marked reduction of cases 4 months post cyclone. The cure, death and non-recovery rate outcome indicators were desirable; however, defaulter rate compromised the effectiveness of the IMAM programme. These findings warrant the strengthening and establishment of effective defaulter follow up systems in displaced and hard to reach areas.
Assessment of Ecological Degradation and Associated Implications in Southern Akwa Ibom State: Why Actions need to be Taken
Authors: Sampson Ebong Mbuotidem
Published: April 2022

This study was carried out in Southern part of Akwa Ibom State with a view to unveiling the ecological problems prevalent in the region and its associated implications. Seven Local Government Areas within the region were selected for the study. Two (2) villages in each Local Government were further sampled making a total of 14 villages. The study employed both descriptive and quantitative method of data analysis. Twenty-eight (28) structured questionnaires out of 392 were distributed to Fourteen (14) communities, together with personal interview conducted at the sampled communities. SPSS manipulation using multiple regression analysis revealed that the Southern Akwa Ibom State is heavily endowed with natural resources and in the quest of harnessing the resources, a wide variety of ecological problems emerged such as oil spill, forest destruction, gas flaring, water pollution, air pollution, open defecation, ground water contamination, soil acidity and biodiversity loss. The study further noted that given the ever-increasing ecological degradation, the livelihood and socio-economic status of the region have been modified, jeopardized or absolutely destabilized with poor crop yield, fishery loss, soil infertility and land contaminant. It was however recommended that an impact prediction and proper assessment of anthropogenic activities including mineral and non-mineral exploitation within the area be carried out. This is with a view to touching essentially on the change brought about by anthropogenic activities including, sand dredging, deforestation, gas flaring as well as oil spill which subsequently impact upon agricultural productivity and environmental resources in the region. Also, all the key stakeholders in the various companies operating within the region including oil and gas industry should inject some funds and re-direct their attention toward effective ecosystem management for improved livelihood sustainability.
Land use Pattern in Coastal Areas of Lagos State: Issues and Challenges
Authors: Akinwunmi Akinpelu
Published: April 2022

An explosion in population, economic development in coastal cities worldwide lead to severe issues and challenges. One reason is that physical planning faces diverse social, economic and political challenges which hinder an organized and planned urban development, therefore leading to issues. This paper examines land use pattern in the coastal area of Lagos state: issues and challenges using both primary and secondary data. The result of the remote sensing analysis of google earth exposed that urban development was stronger in the study area (3.6% increase between 2011, 4.7% increase between 2017, and 12.5% between 2020). Also, the study showed that land-use planning flops due to the lack of implementation of legal regulations, laws, population surge. The study recommends the development of strategies that discourage the disturbance of swamp habitat and funding of more research on the implication of land use, health and life expectancy, and wetlands.
Aspects Complementary to the Teaching of Environmental Education in Changing Attitudes about High Andean Solid Waste
Authors: Urbano Jesus Javier Naccha
Published: April 2022

The objective of the study was to determine the effectiveness of a didactic unit as an environmental education strategy, in initial education students of the National University of San Cristóbal de Huamanga, of the Natural Sciences subject, applying the competence of attitude towards waste solid. The population consisted of the entire population of all students enrolled in the Natural Sciences course 2017-I. The type of research was descriptive and the design was cross-sectional. As instruments for data collection, the pretest and posttest were used, where knowledge about attitudes about solid waste is reported. 21% of students failed the pretest and 100% passed the posttest. Student learning improved significantly with the application of the didactic unit, as an environmental education strategy in the Natural Sciences course, and the students' attitude about solid waste was positive.
Influence of Radioactive Isotopes from Soil on the Growth and Development of Different Plant Cultures
Authors: Markovi Jelena
Published: April 2022

This paper presents the results of a research on the natural and artificial radioactivity of agricultural land in the surrounding villages of the city of Vranje, in the south of Serbia. The characteristic values of specific activity of 226Ra, 232Th, 238U and 235U and 40K were analyzed, as representatives of the natural radioactivity and of 137Cs, as representative of artificial, human activity. The results of the research show the low values of radionuclides of some values are even below the detection limit, which is good for the population. Further research should be continued in the direction of a continued monitoring and development of new improved removal technologies, since small amounts of radionuclides in the soil, through plants, can adversely affect the human health and environment.
Rainfall Anomaly Index Valuation of Agricultural Production in Jakiri Sub-Division, Northwest Region, Cameroon
Authors: Tume Suiven John Paul
Published: April 2022

This paper aims to evaluate the impact of rainfall variability on agricultural production in Jakiri Sub-Division of the Northwest Region of Cameroon. Previous studies on the impact of climate on agriculture focused on stakeholder signatures to climate change adaptation to the agrarian sector of the Bui Plateau, which revealed that despites glaring consequences of climate, the Jakiri Council only allocates only 1% of its annual budget for climate action. Data sources for this study included the administration of 211 questionnaires to cover the three agro-ecological zones of Jakiri Sub-Division, rainfall data collected from UNVDA Ndop (lowland zone), National Meteorological Service (mid-altitude zone) and the Oku Wildlife Sanctuary (highland zone). The Rainfall Anomaly Index (RAI) was used in analysing rainfall data. Results revealed that rainfall is reducing as depicted by the increasing trends in RAI. Farmers also perceived that food crop production has been decreasing. Despite these perceptions, some crops like cassava that is drought tolerant has been increasing. Again, rice production at the WahsiBer Plain has been increasing. This calls for the development and production of more drought tolerant food crops to ensure sustainable rural livelihoods.
About Conservation Status of Northern Lapwing Vanellus vanellus in Armenia
Authors: Aghababyan Karen
Published: April 2022

Population monitoring of Northern Lapwing (NL) was conducted in Armenia during 2003–2019 and demonstrated that NL disappeared in three 10x10 km squares. The total AOO of NL is estimated as 496 km2 , the EOO, as 20,744 km2 . Estimation of national population in 2019 makes 860–1120 breeding pairs. In 2003-2019, the population trend showed a moderate decline (Wald-Test = 10.47, df = 15, p = 0.7891; Overall slope model: Additive = -0.0128, SE = 0.0052, Multiplicative = 0.9873, SE = 0.0052; p < 0.05). The observed decrease makes -26% during 17 years (-1.53% per annum), the estimated decrease makes -43% during 27 years (three generations of NL). The hunting pressures NL via exceeding the daily bag limits, and by shooting NL, when prohibited. The State Inspection has a difficulty in controlling the hunting and poaching being understaffed and underfinanced. In livestock husbandry, the number of NL decreases with an increase of cattle (R2 = 0.425, F1,15 = 11.079, p = 0.005), most probably due to increased mowing. Currently NL qualifies for Armenian Red List as Vulnerable A2bc + B2abv + C1. To protect NL, the current candidate Emerald Sites should become official ones protected by Bern Convention, the current public hunting lands should be excluded from Emerald Sites, and current agricultural practices should be reviewed, changing the way of machinery mowing. The mechanism of hunting licencing should include strict hunters’ exam. The State Inspection should start cooperation with hunters’ unions. The continued monitoring of NL remains essential.
Sand Dredging in Anyang River and its Implication on Morphological Structure in Edebom II, Nsit Ibom, Akwa Ibom State, Nigeria
Authors: Abraham Comfort
Published: April 2022

This study focused on sand dredging in Anyang Nsit River and its implication on morphological structure in Edebom II, Nsit Ibom, Akwa Ibom State, Nigeria, a third order tributary of Kwa Iboe river basin, which entails the morphometric parameters, dredging induced hazards, measurement and calculation of hydraulic parameters at two high dredging sites, are related to the dynamic nature of the river channel. Digital Elevation Model (DEM) of the study area with resolution 30x30m was obtained from United States Geological Survey (USGS) and the river channel was delineated. With the aid of Arc GIS 10.3 software package and Erdas Imagine 9.2 software reprojection and the map was produced in the layout view on a scale of 1:187500. The linear, areal and relief aspects of the sub-catchment were derived using strings and constructed grid lines placed on the map, while morphometric parameters of the river channel were calculated using relevant statistical package. The hydraulic parameters (bank full width, mean depth, velocity) of the two dredging sites were measured in a period of four months (MarchJune). The results showed that hydraulic parameters of these dredging points have changed significantly within this period. The calculated channel discharge had increased by 10m3/s and 7.42m3/s respectively at the two dredging sites. A total of 26,804 tonnes of dry weight sand is dredged both manually and mechanically (hydraulically) between March-June, 2021 which is consistent with the assertion that sand dredging is responsible for the change in the channel morphology especially in depth and deformation of channel configuration parameters. It was recommended that sand dredging in Akwa Ibom should be monitored by the Ministry of Environment as a statutory responsibility to maintain morphometric parameters in Akwa Ibom State, Nigeria.
Potential Impact of Climate Variability on Tea Farming on the Mambilla Plateau, Taraba State, Nigeria
Authors: ED Oruonye
Published: April 2022

This study examined the potential impact of climate variability on tea farming on the Mambilla Plateau, Taraba State, Nigeria. Data for this study was generated through primary and secondary sources. The primary data were generated from field observation. Secondary desk review of existing literature and online resources were used. Archival data on climatic elements were obtained from the Upper Benue River Basin Development Authority (UBRBDA) Meteorological stations at Gembu and Maisamari, both on the Mambilla plateau. The data was analyzed using inferential statistics such as simple correlation coefficient (r), regression and time series analysis. The result of the findings on the trends of annual rainfall in the study area shows that rainfall amount, length of rainy season (LRS) and relative humidity were decreasing, with late onset and cessation of rains in the area. The trend of maximum and minimum temperature as well as wind speed was increasing owing to increasing rate of deforestation in the area. Climate variability and change has both advantages and disadvantages to the growth and development of tea which ultimately affect its production. Variability in precipitation and temperature has considerable impacts on tea quality and yields by altering the quantities and types of pests and weeds in and around tea farms. The findings of the study reveal that the global surface temperature has changed and will continue to change in the nearest future. Hence, the need to devise suitable means of adaptation and mitigation to the challenges of climate change in the area. Based on the findings, the study recommends the use of improved tea crop variety, involvement of local communities in climate change adaptation strategies, increase dissemination of climate information and education of the farmers on most suitable local adaptation strategies.
White Storks Ciconia ciconia L. became Victims of Environmental Pollution of Ararat Plain of Armenia
Authors: Aghababyan Karen
Published: April 2022

The novelty threat to White Storks Ciconia ciconia in Armenia was investigated in 33 villages of Ararat Plain in 2019-2021. The Storks were becoming smeared with the undetermined agent of plant oil and/or fish fat nature, which was impeding their flying abilities. In 2019 smeared Storks were found in five villages, with total number of 125 smeared nestlings and 84 smeared adult storks. In 2020 smeared Storks were found in 15 villages, in 95 nests, totaling to 285 smeared nestlings and 192 smeared adults. In 2021 smeared Storks were found in 28 villages, in 178 nests, totaling to 534 smeared nestlings and 356 smeared adults. Average percent of the polluted nestlings grew from 5% in 2019 to 21% in 2020 (t=3.62, df=32, p<0.001), and then to 58% in 2021 (t=7.17, df=32, p<0.05). The most likely causes of environmental pollution and Storks’ smearing are Sturgeon farms and producers of canned food. Current legislation provides with necessary tools to deal with possible polluters; however there is a need to enforce the laws. Therefore, a number of short-term and long-term measures are suggested to improve the situation.
Optimasi Nilai Parameter pada Metode Brown’s Exponential Smoothing dengan Algoritma Multiple Genetik
Authors: Sudiatmika Anop , Indrawan Gede , Divayana Dewa Gede Hendra
Published: April 2022

Untuk mendapatkan nilai alpha paling optimal untuk metode Brown's Double Exponential Smoothing (Brown's-DES) dapat menggunakan metode algoritma genetika. Namun, Kekurangan dari algoritma genetika yaitu memerlukan generasi yang banyak untuk menghasilkan sebuah nilai yang optimal. Perlu banyak iterasi yang harus dilakukan jika ingin mendapatkan nilai paling optimal dan presisi. Banyaknya iterasi akan berpengaruh pada kecepatan algoritma dalam menemukan nilai paling optimal. Maka dari itu, peneliti mengembangkan algoritma multiple genetik yang terinspirasi dari algoritma genetik. Algoritma yang dikembangkan mampu menemukan nilai alpha paling optimal dan lebih presisi dengan meminimalkan generasi yang diperlukan dalam algoritma. Dengan menerapkan algoritma multi genetika dua tingkat, didapatkan nilai alpha 0,74 dengan persentase MAPE 1,3224% dibandingkan dengan algoritma genetika biasa yang mendpatkan nilai alpha 0,7 dengan persentase MAPE 1,3456%. Semakin besar tingkatan algoritma multi genetika yang diterapkan, maka hasil alpha yang didapatkan akan semakin optimal dan presisi.
Usability Testing pada Sistem Informasi Manajemen AKN Pacitan Menggunakan Metode System Usability Scale
Authors: Nugroho Kurnianto Tri , Julianto Bagus , Nur MS Danny Febryan
Published: April 2022

Penerapan smart campus pada Akademi Komuntias Negeri (AKN) Pacitan, salah satunya bertujuan untuk meningkatkan pelayanan publik. Sistem informasi manajemen merupakan bagian dari smart campus yang ada pada AKN Pacitan. Untuk mengetahui kualitas layanan dari pandangan pengguna sistem informasi ini, maka dibuatlah suatu pengujian usability. Usability merupakan analisis kualitatif dalam menentukan kualitas suatu sistem informasi berdasarkan kemudahan user dalam menggunakan sistem informasi. Tujuan dari penelitian ini adalah untuk menganalisis tingkat usability pada sistem informasi manajemen AKN Pacitan. Sejauh ini terdapat beberapa metode dalam evaluasi salah satunya adalah metode System Usability Scale (SUS). Populasi penelitian ini adalah dosen, staff dan mahasiswa AKN Pacitan, menggunakan probability sampling  sebagai teknik pengambilan data. Data penelitian ini diambil dengan menggunakan kuisioner dan dianalisis menggunakan metode analisis deskriptif. Berdasarkan hasil pengujian usability, mayoritas responden menggunakan dan memanfaatkan sistem informasi ini dengan baik. Hal ini dibuktikan dengan total hasil nilai pengujian sebesar 71,48. Dari segi acceptability range sistem informasi ini masuk ke kategori acceptable, sedangkan pada grade scale berada pada posisi grade C dan pada adjective rating berada pada posisi good.  Dapat disimpulkan bahwa sistem informasi ini dapat dijadikan alat bantu perkuliahan khususnya untuk memasukan jurnal kuliah, presensi dan nilai.
CONCEPTUAL FOUNDATIONS OF LEGAL RESPONSIBILITY IN CIVIL PROCEDURE
Authors: ZAGIDULLIN M.R.
Published: April 2022

Despite the ongoing reforms, today a very large number of procedural violations committed by participants in the proceedings continues to be observed during the consideration of judicial disputes, largely due to the inefficiency or insufficiency of the legal liability measures currently in force. There is also a high degree of inconsistency in law enforcement practice regarding the application of procedural liability measures for unfair procedural behavior, late or incomplete presentation of evidence, and delay in the trial. The author also presents the most acute problems of legal regulation of legal liability and outlines specific proposals to overcome them. The article presents the thesis that it is characteristic and necessary for the adversarial model that legal liability is closely interrelated with the model of the adversarial model of civil proceedings, differing in the degree of development and substantive characteristics of measures against unfair procedural behavior, proportionality (proportionality) of the size of punitive liability were proportional to the price of the claim, the active use of legal fictions / presumptions. It is concluded that it is necessary to develop and scientifically substantiate a new model of legal responsibility in the entire civil procedure. This model should be based on the following conceptual foundations: uniform legal regulation of legal liability in the framework of the entire civil procedure; strengthening of adversarial principles in the implementation of legal responsibility, including by improving liability measures against unfair procedural behavior, etc.; the introduction in non-judicial civil jurisdictions of rating systems for evaluating the activities of bodies and persons engaged in procedural and procedural activities, and the application of legal liability measures based on them.
ON THE FORMATION AND DEVELOPMENT OF CIVIL PROCEDURE IN RUSSIAN LAW IN THE 9TH–15TH CENTURIES
Authors: MEDVEDEV V.G. , LIPINSKY D.A.
Published: April 2022

The article reveals the issues of the formation and development of civil procedure law in medieval Russia on the basis of various historical and legal sources and the works of Russian, Soviet and modern scientists. The relevance of the work lies in the fact that this problem remains insufficiently investigated to date due to the small number of works devoted directly to the civil process in the Old Russian state and Northwestern Russia during the period of feudal fragmentation. The novelty of the study is associated with the identification of some new features of civil proceedings and a new interpretation of existing provisions. The methodology used in the course of the study includes dialectical, comparative-historical, formal, logical and hermeneutic methods that allowed us to consider the formation of civil procedure law in its development and its relationship with the phenomena of socioeconomic life, compare historical and legal sources of various periods of medieval statehood, analyze these sources and interpret them. In the course of the study, it was revealed that the formation of civil proceedings was closely connected with the judicial system of Ancient Russia, Novgorod and Pskov. It is determined that, despite the unity of the criminal and civil proceedings in the Kievan state, some differences have already been observed in them. The procedural legal capacity of participants in civil proceedings in Kiev and North-Western Russia has been established. The duality of the judicial system and the separate jurisdiction of the princely and republican judicial bodies in Novgorod and Pskov were revealed and new stages of civil proceedings were established. Conclusions: in Ancient Russia, due to the underdevelopment of commodity-money relations, only the beginnings of the formation of judicial power and civil proceedings were observed. During the period of feudal fragmentation in economically developed Novgorod and Pskov, the judicial system and civil procedure law received significant development. Along with the immutability of the principle of the adversarial process, many new provisions have appeared in it. Women, elderly people and children were given the right to present their representatives at the trial, there were rules on the public summoning of the defendant to court, the process became closed, oral clerical work was replaced by written, the evidence base expanded due to a judicial duel and written evidence.
RECOGNITION AND ENFORCEMENT OF FOREIGN JUDGMENTS ON TAX, CUSTOMS AND OTHER ADMINISTRATIVE MONETARY PENALTIES: A DILEMMA OF PRIVATE INTERNATIONAL AND PUBLIC INTERNATIONAL LAW
Authors: TARASOVA A.E. , EVSIKOV M.V.
Published: April 2022

This article considers the problem of foreign court decisions execution on tax, customs and other administrative monetary penalties through the prism and mechanisms of private international law and international economic law. The approaches of Russian tax service and Russian courts on the given issue are analysed, the normative and doctrinal peculiarities of Russian jurisdiction are pointed out. International treaties in the field of private international law, including international civil procedure and international economic law that are (or could be) applied to the solution of this problem are considered. Examples are given to illustrate attempts to enforce foreign adjudication of customs duties in Russia. Historical background and doctrinal limitations of foreign adjudication in this field have been studied; the revenue rule principle in the Anglo-American countries has also been considered in detail. The article provides a comparison between the approaches of different jurisdictions as well as an analysis of the current trends. The authors also describe current regional and global mechanisms of cooperation in tax collection, including interdepartmental cooperation between the public agencies of different countries. On the basis of recent trends the authors suggest possible variants to solve investigated problem; they also estimate perspectives of jurisdictions interaction at mutual execution of foreign court decisions; they emphasize the role of supranational international law in the framework of regional economic integration unions; they highlight risks of using private law international mechanisms of recognition and enforcement of decisions in public sphere.
IS IT PERMISSIBLE FOR THE COURTS TO INTRUDE INTO THE COMPETENCE OF OTHER AUTHORITIES?
Authors: TUMANOV D.A.
Published: April 2022

The article deals with the question of the admissibility of courts’ intrusion into the sphere of competence of other authorities. In the USSR, and later in the Russian Federation, an approach was developed according to which judicial control cannot concern those issues which are attributed to the exclusive competence of the legislative and executive authorities and whose solution is connected with their discretion. At present, to justify this impossibility they refer to the principle of separation of powers. But after all, the main purpose of such a principle is to prevent the absolutization of power. While the existence of areas inaccessible to judicial control, just becomes a source of arbitrariness of the legislative and executive powers. The article demonstrates that judicial control in Russia should also cover those acts, actions (inaction) of the authorities, the adoption or commission of which is based on their discretion, and it is this approach that truly corresponds to the principle of separation of powers. Examples are given of situations where significant issues for society that are within the discretion of the legislative and executive powers are not resolved, which significantly violates the public interest. The society would benefit from court intervention to solve such issues. The author considers possible variants of court intervention in the solution of socially significant issues.
ABUSE OF PROCEDURAL RIGHTS: THE RELATIONSHIP BETWEEN THE SPIRIT AND THE LETTER OF THE LAW
Authors: FOKINA M.A.
Published: April 2022

The article deals with the correlation between the concepts “letter of the law” and “spirit of the law” in correlation with the concepts of good faith and abuse of procedural rights. The author points out that if the “spirit of the law” is not clear enough, there is an abuse of the “letter of the law”. In this case the law turns into a tool which is used by its enforcers not for the purposes of justice but for their own purposes. As a result of the study of controversial issues of the concept of good faith behavior of subjects of procedural law in civil proceedings, it is concluded that “good faith”, and especially “inadmissibility of abuse of procedural rights” cannot be considered as principles of civil and arbitration proceedings, administrative proceedings. The article specifies the condition under which the behavior will be considered as bona fide, namely: when it corresponds to the goals and objectives of civil and arbitral protsesses, administrative proceedings. The application of the current and projected legislation on the problems of combating the abuse of procedural rights is analyzed.
A Novel Framework for Selecting Elicitation Technique based on Attribute Mapping
Authors: Ahmed Attique , Naeem Muhammad
Published: April 2022

The software development process is completely based on the requirements of stakeholders. If the requirements of stakeholders are being integrated into the proposed system, then it can be assumed that the end product is going to be optimal and successful. To achieve a successful product, different Requirement Elicitation Techniques (RET) are being practiced. The selection of a suitable RET is based on the nature of the product being developed. So, a single RET doesn’t fit all products. In this paper, we differentiate all RETs from each other which makes it easier for an analyst to choose suitable RET from the available ones. We further designed a novel mapping framework that extracts the best suited RET to any software based on its attributes. We have further implemented the proposed framework by using an online vehicle booking system as a running example.
Teori Pembangunan Ekonomi
Authors: Lestari Nelly , Pasha Putri Aisha , Oktapianti Merisa , Noviarita Heni
Published: April 2022

Penelitian ini berangkat dari permasalahan mengenai pembangunan. Pembangunan adalah pertumbuhan dan perubahan ke arah yang lebih baik. Setiap pembangunan bertujuan untuk mensejahterakan rakyatnya. Pembangunan awalnya dipakai dalam arti pertumbuhan ekonomi masyarakat. Karena, sebuah masyarakat akan dinilai berhasil melaksanakan pembangunan, bila pertumbuhan ekonomi masyarakat tersebut sangat tinggi dan mengalami perubahan.Penelitian ini didasarkan pada teori pembangunan oleh beberapa ahli yakni Rostow dan Lewis. Teori Arthus Lewis pada dasarnya membahas proses pembangunan ekonomi yang terjadi di daerah pedesaan dan daerah perkotaan (urban). Sedangkan Menurut Rostow, pembangunan ekonomi atau proses transformasi suatu masyarakat tradisional menjadi masyarakat moderen merupakan suatu proses yang multidimensional.Salah satu indikator keberhasilan pelaksanaan pembangunan yang dapat dijadikan tolak ukur secara makro adalah pertumbuhan ekonomi. Akan tetapi, meskipun telah digunakan sebagai indikator pembangunan, pertumbuhan ekonomi masih bersifat umum dan belum mencerminkan kemampuan masyarakat secara individual. Pembangunan daerah diharapkan akan membawa dampak positif pula terhadap pertumbuhan ekonomi.
GENETIC MARKERS OF OBESITY IN PATIENTS WITH ARTERIAL HYPERTENSION
Authors: Sydorchuk A.R. , Harbuzova V.Yu. , Gutnitska A.F.
Published: April 2022

More than 50% of patients with essential arterial hypertension (EAH) have additionalcardiovascular risk factors, among which the most common are obesity, diabetes mellitus,metabolic syndrome, etc.Objective – to investigate polymorphic variants of the NOS3 (rs2070744) and GNB3(rs5443) genes as markers of obesity in EAH patients.Material and methods. 100 patients with EAH and 48 practically healthy (control group)participated in the study. All participants underwent clinical and laboratory examinations.Obesity was determined by body mass index (BMI) ≥30 kg/m2. GNB3 (rs5443) and NOS3(rs2070744) genes genotyping was performed by Real-Time PCR. Risks were studied bythe clinical epidemiology method.Results. In EAH patients the mutation of the NOS3 gene in the homozygous state occurswith a frequency of 16.67%, and for the GNB3 gene – 8.33% of cases, which does notdiffer from the control group. The relative frequency of obese people prevailed among EAHpatients with the mutational C-allele carriers of the NOS3 gene by 31.94% (χ2=13.58;p<0.001) and in patients with mutational T-allele of the GNB3 gene (30.56%) in theabsence of such among the healthy. The risk of obesity increases in EAH patients withthe C-allele carriers of the NOS3 gene almost 6 times [OR 95%CI:2.11-14.82; p<0.001]and in T-allele patients of the GNB3 gene – more than 10 times [OR 95%CI:2.25-45.44;p<0.001]. The TT-genotype of the NOS3 gene and the CC-genotype of the GNB3 geneplay a protective role against obesity.Conclusion. The C-allele of the NOS3 gene (rs2070744) and the T-allele of the GNB3gene (rs5443) increase the obesity risk of in arterial hypertensive patients 6 and 10 times(p<0.001).
KEY MOLECULAR GENETIC REGULATORS OF PANCREATIC ENDOCRINOCYTE DIFFERENTIATION
Authors: Ivanenko T.V. , Vynokurova A.V.
Published: April 2022

The aim of this study - to review the literature data regarding the group of the mostpopular and active genes involved in the endocrine pancreas development.Conclusions. The transcription factors and markers, determining cells types, activelyoperate in the pancreas during embryogenesis. Among key differentiation-related genesare endocrine pancreas master regulator Neurogenin-3 (Ngn3), alpha cell-specificgenes - Рах 6, Arx, Maf-B, Nkx-2.2, Nkx-6.2; beta cell specific transcription factors -Pax 4, Maf-A, Maf-B, Nkx-6.1, Nkx-2.2, PDX-1; delta cells - Pax-6, Pax-4; progenitorcell marker C-kit.Regulatory proteins encoded by these genes control mechanisms ofendocrinocyte differentiation, which are active not only during embryogenesis, but alsocontinue to induce endocrine cell formation during adult life, including those influencedby exogenous and endogenous factors, when new islets are generated from ductal cells.Each of the above-mentioned genes is functionally important at different stages ofdetermination and differentiation of pancreatic cells, and mutation at least in one ofthese genes could cause severe disorders in the development and functioning of theorgan. Genes, taken into consideration, play an important role not only in the period ofpancreas embryonic development, but also essential for the normal functioning of betacells throughout life, since various pathological conditions are associated with mutationsin these genes. Processes such as hypoxia, hypertension, diabetes mellitus could influencethe level of gene expression during progenitor cell differentiation, thus determining theendocrinocyte population density in the pancreas over time through the commitment ofprogenitor cells that maintain basal homeostasis.
HYPERURICEMY: EFFECT ON THE CHRONIC HEART FAILURE PATHOGENESIS
Authors: Tashchuk V.K. , Hrebtii H.I. , Vovchok T.S. , Vintoniak М.О. , Anfilofiieva V.V.
Published: April 2022

Purpose - a literature review of the published clinical studies on the effects ofhyperuricemy on the chronic heart failure course(CHF).Conclusions. Studies show that uric acid is associated with cardiovascular disease, and hyperuricemy is common in patients with CHF. Hyperuricemy is associated withimpaired peripheral blood flow and decreased vascular dilatation, which is closelycorrelated with clinical status and reduced physical ability. Recent studies also suggesta close correlation between uric acid levels and myocardial diastolic function and,more importantly, uric acid is determined by a strong, independent prognostic predictorin CHF patients. Current experimental and clinical studies have shown that inhibitionof xanthine oxidase causes significant beneficial pathophysiological changes. Evidenceof this effect suggests that myocardial energy metabolism, endothelial dysfunction,and exercise tolerance are improved at the expense of the decrease of oxidative stressmanifestations, therefore, lowering of the serum levels of the uric acid is a promisingtherapeutic target for improving the treatment of CHF patients.
SCIENTIFIC AND PEDAGOGICAL HERITAGE OF PROFESSOR HALYNA ANTONIVNA TROYAN (TO THE 100 ANNIVERSARY OF HER BIRTH)
Authors: Deineka S.Ye. , Sydorchuk L.I. , Mikheev А.О.
Published: April 2022

The article provides basic information about the creative path in science and theoreticalmedicine of the famous scientist, head of the Department of Microbiology, Virology andImmunology of Chernivtsi Medical Institute, Dean of the Medical Faculty, Excellencein Healthcare, Doctor of Medical Sciences, Professor Halina Antonivna Troyan, whoworked fruitfully in ChMI from 1953 to 1970. She served on the fronts of World War II asa nurse in various hospitals of the active army, for which she was awarded three battlemedals. H.A. Troyan made a significant contribution to the development of domesticmicrobiology, virology and immunology, and founded a powerful scientific school ofmicrobiology (6 candidates of medical sciences). Her enthusiastic work is recognized andworthy of inheritance, and her grateful followers still pass on the baton of their Master.
PHARMACO-ECONOMIC INDICATORS OF ACUTE BRONCHITIS TREATMENT IN CHILDREN
Authors: Nechytailo Yu.M. , Popelyuk N.O. , Dolzhenko O.G. , Bogdanova L.O. , Kovtyuk N.I. , Mabrouk Ben Othmen
Published: April 2022

The goal - to analyze the features of treatment and medical expenses in childrenhospitalized for acute bronchitis.Material and methods. The study analyzed medical records and examined 30 childrenaged 3 to 11 years hospitalized for acute bronchitis. Peculiarities of clinical symptoms,structure of the treatment measures and their cost were studiedThe results. The length of hospital stay was 7.4 ± 0.53 days with subsequent therapyand rehabilitation in an outpatient setting. Antibiotics, antipyretics, antihistamines,mucolytics and corticosteroid hormones were used in the treatment. The total cost ofone case treatment was on average 674.2 ± 80.9 hryvnias. The most expensive werethe costs of infusion therapy and antibiotics, which were prescribed to about a third ofpatients, and the cheapest - antipyretics. Taking into account the age of the children, theacute nature of the process, antibiotics’ use from the reserve group was irrational andsignificantly increased the cost of the treatment.Conclusions. The introduction of a new model of medicine has a positive effect onthe optimization of acute bronchitis treatment tactics from shifting the emphasis fromintensive antibacterial therapy to the restoration of mucociliary clearance. The choiceof antibacterial drugs was still an irrational, from a clinical and economic point ofview.