bluuebunny/crossref_metadata_2025 huggingface dataset:
On the possibility of using ceramic highly porous block-cellular materials as contact sorption-filtering elements
Authors:   Mendeleev University of Chemical Technology of Russia, Gasparyan M. D. , Grunsky V. N. ,   Mendeleev University of Chemical Technology of Russia, Davidkhanova M. G. ,   Mendeleev University of Chemical Technology of Russia, Grigorenko R. I. ,   Mendeleev University of Chemical Technology of Russia
Published: September 2021

The paper considers the structural and physical characteristics of carriers based on ceramic highly porous block materials of a cellular structure, which provide the sorption-filtering properties of contact elements. Methods for determining the external specific volumetric surface, gas-dynamic resistance and gas permeability are described. Their interrelation and optimal combination with the operational characteristics of sorbent filters in the processes of capturing volatile compounds of iodine and cesium in gas streams is shown. The results obtained can be used to synthesize contact elements of a new class and create on their basis highly efficient gas cleaning systems operating at high temperatures and corrosive environments.
Investigation of the cavitation strength of protective coatings under abnormal conditions
Authors:   Biysk Technological Institute (branch) of the Altay State Technical University, Khmelev V. N. , Barsukov R. V. ,   Biysk Technological Institute (branch) of the Altay State Technical University, Golykh R. N. ,   Biysk Technological Institute (branch) of the Altay State Technical University, Genne D. V. ,   Ltd «Сenter of ultrasonic technologies», Abramenko D. A. ,   Biysk Technological Institute (branch) of the Altay State Technical University, Tsyganok S. N. ,   Biysk Technological Institute (branch) of the Altay State Technical University, Barsukov A. R. ,   Biysk Technological Institute (branch) of the Altay State Technical University
Published: September 2021

One of the possible mechanisms for the destruction of metals and other materials is cavitation. Acoustic cavitation occurs in liquid media when high-intensity acoustic vibrations propagate in them. The article discusses the features of the method for studying the cavitation strength of protective coatings (including under abnormal conditions). The method is based on the control of cavitation phenomena in the voiced medium, by controlling the parameters of ultrasonic emitters. It is shown that the parameters of ultrasonic emitters are affected by the size of the gap between the emitting and reflecting surfaces. The results obtained in the work show that the implementation of the control of the cavitation strength of coatings at various temperatures and pressures requires the use of continuous control to automatically eliminate this effect by optimizing the intensity of the impact.
Arriba y abajo: el persistente poder de los imaginarios estatales y tribales en la configuración de los Andes y la Amazonía
Authors: Santos Granero Fernando
Published: September 2021

Este artículo examina la divisoria entre Andes y Amazonía como el producto de relaciones históricas de larga duración. Se sostiene que esta escisión no es un fenómeno reciente vinculado a la construcción de los estados-nación sudamericanos, sino que precede a la conquista española de América por varios milenios. Tiene poco que ver con la ecología y mucho con el poder y las filosofías políticas. Es el resultado del choque entre dos ideales opuestos de socialidad y poder, que encuentran expresión en imaginarios sociales antitéticos. Mientras que las sociedades estatales andinas veían la Amazonia como una “zona tribal”, oscura y místicamente poderosa, las sociedades igualitarias de la alta Amazonía veían los Andes como una tierra de maldad, llena de maravillas tecnológicas pero peligrosa para la consolidación de una vida social armoniosa. Esta confrontación puede entenderse como una confrontación entre “estados” y “tribus” que se remonta al surgimiento de las primeras formaciones estatales en los Andes alrededor del año 2000 a. C. Sin embargo, hay que tener cuidado de no otorgar a estas representaciones ideológicas más poder del que realmente tenían. En el texto se sostiene que, si bien los pueblos indígenas andinos y amazónicos se representaban mutuamente como otros salvajes y primitivos, existe abundante evidencia de que la interacción entre ellos fue permanente, intensiva y fructífera.
De la salvación individual al buen gobierno colonial: apuntes sobre censos de indios (1558-1581)
Authors: Tapia Franco Luis Alfredo
Published: September 2021

El artículo trata sobre el origen de las rentas censales de las comunidades de indios en tanto actos de restitución de los encomenderos, y el nuevo uso dado a tales rentas como parte de las reformas introducidas durante el gobierno del virrey Francisco de Toledo. Este virrey se abocó básicamente a mejorar e implementar el marco institucional de los censos en general, pero también dirigió su atención a definir responsabilidades y centralizar la cobranza y administración de los censos de indios.
El desembarco de Cristóbal Colón en Lima: la historia de su estatua y de sus traslados
Authors: Coello Rodríguez Antonio
Published: September 2021

El presente artículo desarrolla la historia del monumento a Cristóbal Colón y sus continuos traslados por la ciudad de Lima. Asimismo, explica por qué se escogió su primera ubicación, colindante a la Plaza Acho, zona muy distante para aquella Lima de la segunda mitad del siglo XIX, que fue considerada en los planes de la Municipalidad de Lima con fines de mejorarla y hacerla más atractiva a los limeños de aquellas épocas. Sin embargo, dicho proyecto no prosperó debido a los continuos asaltos y robos, razón por la cual se decidió su cambio a una nueva zona que represente el progreso y orden: el Parque de la Exposición, en cuyas inmediaciones dará varias vueltas, hasta inaugurarse el paseo 9 de Diciembre, hoy paseo Colón, lugar definitivo de dicho monumento.
Essential clinical and diagnostic aspects in pediatric psoriasis
Authors:   Disciplina Medicină de familie, Universitatea de Medicină și Farmacie “Carol Davila”, București, România, STĂNESCU Ana Maria Alexandra , GRĂJDEANU Ioana Veronica ,   Disciplina Medicină de familie, Universitatea de Medicină și Farmacie “Carol Davila”, București, România, SIMIONESCU Anca Angela ,   Disciplina Obstetrică-Ginecologie, Spitalul Clinic Filantropia, București, România,   Disciplina Obstetrică-Ginecologie,, Universitatea de Medicină și Farmacie “Carol Davila”, București, România, FLOREA Mira ,   Disciplina Medicină de familie, Universitatea de Medicină și Farmacie „Iuliu Haţieganu“, Cluj-Napoca, România
Published: September 2021

Psoriasis is a chronic, immune-mediated, inflammatory disease of the skin. The quality of life is significantly affected, being characterized by relapses, remissions and the presence of comorbidities associated with psoriasis. Several factors are implicated in the onset of psoriasis in children, including: genetic factors, environmental factors, psychosocial stress, obesity, trauma, skin irritation, use of certain drugs such as lithium, β-adrenergic antagonists and necrosis factor inhibitors. (TNF), the presence of Crohn's disease or juvenile rheumatoid arthritis. Psoriasis is a burden for the patient in the case of the adult, being even more difficult in the case of children. Atypical manifestations in pediatric psoriasis can be difficult to diagnose.
Vaping and alternative smoking methods – a new risk of toxicity in children and adolescents
Authors:   Universitatea de Medicină și Farmacie „Carol Davila“, București, România, NIȚESCU Gabriela Viorela ,   Centrul Antitoxic Pediatric, Spitalul Clinic de Urgență pentru Copii „Grigore Alexandrescu“, București, România, BOGHIȚOIU Dora Andreea ,   Universitatea de Medicină și Farmacie „Carol Davila“, București, România,   Centrul Antitoxic Pediatric, Spitalul Clinic de Urgență pentru Copii „Grigore Alexandrescu“, București, România, SIMIONESCU Anca Angela ,   Universitatea de Medicină și Farmacie „Carol Davila“, București, România,   Departamentul de Obstetrică și Ginecologie, Spitalul Filantropia, București, România, ULMEANU Coriolan Emil ,   Universitatea de Medicină și Farmacie „Carol Davila“, București, România,   Centrul Antitoxic Pediatric, Spitalul Clinic de Urgență pentru Copii „Grigore Alexandrescu“, București, România
Published: September 2021

The children’s use of e-cigarettes has increased as many view them as a safer alternative to smoking during the past few years. In e-cigarettes, tobacco combustion is replaced by e-liquid heating, but the heating process can lead to new decomposition compounds of questionable toxicity. In addition, children exposure to e-cigarette liquids, whether intentional or accidental, may lead to specific adverse events of various types and severity from acute nicotine poisoning to an e-cigarette or vaping use-associated lung injury (EVALI), a severe pulmonary disease with public health implications. Therefore ongoing surveillance of poisoning exposure cases involving e-cigarettes and informing and educating the receptive population, especially adolescents and young people, on the risks they are exposed to by using these alternative smoking methods acquires special importance.
What the neonatologists need to know about the Cantrell’s pentalogy
Authors:   Obstetrică-Ginecologie, Institutul Naţional pentru Sănătatea Mamei şi Copilului „Alessandrescu-Rusescu“, Bucureşti, România, DANCIU Bianca Mihaela , DIMA Vlad ,   Neonatologie, Spitalul Clinic Filantropia, Bucureşti, România, BOGHIȚOIU Dora ,   Spitalul Clinic de Urgenţă pentru Copii „Grigore Alexandrescu”, Bucureşti, România,   Pediatrie, Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti, România, STĂNESCU Ana Maria Alexandra ,   Medicină de familie, Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti, România, SIMIONESCU Anca Angela ,   Obstetrică-Gynecologie, Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti, România,   Obstetrică-Ginecologie, Spitalul Clinic Filantropia, Bucureşti, România
Published: September 2021

Cantrell’s pentalogy is a congenital syndrome that includes multiple defects which predispose the fetus to a high mortality rate. Over time, the association of malformations defining this syndrome has changed accepting incomplete forms, or forms that associate other anomalies. The therapeutic strategy in Cantrell's pentalogy is an intensely debated one as it deals with newborns having a low survival rate and multiple malformations. Once treatment is started for certain malformations it can lead to the aggravation of others. In conclusion, a conservative approach is recommended, with the initiation of surgical treatment after the stabilization of the newborn. A multidisciplinary approach is needed to achieve optimal results in these difficult cases.
Nutrition in the first 6 months of life – current challenges
Authors:   Departamentul Neonatologie, Spitalul Clinic Filantropia, București, România, DIMA Vlad , PREDA Cornelia ,   Departamentul Neonatologie, Spitalul Sanador, București, România, SIMIONESCU Anca ,   Universitatea de Medicină și Farmacie „Carol Davila“,București, România,   Departamentul Obstetrică-Ginecologie, Spitalul Clinic Filantropia, București, România
Published: September 2021

From the moment of birth, the diet must aim an optimal development of the full-term, healthy newborn, and the best known option until now is the breast milk. Studies have consistently highlighted the benefits of natural nutrition, emphasizing its nutritional qualities but also its role in developing immunity for the newborn. A curent challenge is the moment of initiating food diversification, with recommendations indicating ages between 4 and 6 months. Therefore, an analysis of existing recommendations should be linked to studies on the onset of food allergies with the initiation of diversification. There are also cases in which the natural diet cannot be achieved, in these situations the administration of milk formulas is required. Infant mill formulas have evolved a lot in terms of quality and composition, approaching the breast milk, but they can not be considered equal to it.
Considerations of drug administration during breastfeeding
Authors:   Romanian Association of Lactation Consultants, TUDOSE-TRANULIS Ilinca , SIMIONESCU Anca Angela ,   Department of Obstetrics and Gynecology, “Carol Davila“ University of Medicine and Pharmacy, Bucharest, Romania,   Department of Obstetrics and Gynecology, Filantropia Clinical Hospital, Bucharest, Romania, STĂNESCU Ana Maria Alexandra ,   Department of Family Medicine, “Carol Davila“ University of Medicine and Pharmacy, Bucharest, Romania, DIMA Vlad ,   Department of Neonatology, Filantropia Clinical Hospital, Bucharest, Romania
Published: September 2021

Breastmilk is the best nutrition for infants. Unfortunately, almost all breastfeeding mothers require medication at some point during the breastfeeding period, which sometimes leads to the cessation of breastfeeding because of false beliefs about the true risk for the infant. Many prospects drugs information about side effects avoid any administration during pregnancy or in the postpartum period; also, because of fear, mothers choose to stop breastfeeding out, and general practitioners or pediatrist calculate lower doses to administrate. In this article, we want to draw attention to that even though there are no trials in neonates; we have much data on the safe use of medication during breastfeeding. In conclusion, we want to increase awareness about the necessity of increasing knowledge for mothers and healthcare personnel about indications, contraindications, and side effects of most used medication during breastfeeding.
Impact of teeth color determination on dental eshtetic perception
Authors:   Disciplina Protezare Totală, Facultatea de Medicină Dentară, Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti, Drăghici Raluca , Preoteasa Cristina Teodora ,   Disciplina Diagnostic Oro-Dentar, Ergonomie şi Metodologia Cercetării Ştiinţifi ce,  Facultatea de Medicină Dentară, Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti, Tancu Ana Maria Cristina ,   Disciplina Protezare Totală, Facultatea de Medicină Dentară, Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti, Preoteasa Elena ,   Disciplina Protezare Totală, Facultatea de Medicină Dentară, Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti
Published: September 2021

Aim. People with attractive facial appearance are more easily integrated in society and are considered to be more capable, more intelligent and more responsible. The aesthetic aspect is influenced by expression, by facial symmetry, facial contours and teeth colour. In dental restorations, the correct determination of teeth colour is a critical step with extreme importance for successful treatment. From this perspective the practitioner must have experience, must have the ability to distinguish colours and must train through repetitive visual practical exercises that can have an impact on the perception of dental aesthetics. Materials and method. The study followed comparatively the evolution of teeth colour determination and its impact on dental aesthetics perception. It was conducted on a group of fifth year students from the Faculty of Dental Medicine, Bucharest using the Tooth Training Box colour determination exercise that is based on the 3-D Master colour key principle. Results. Using training exercises to determine colour participants developed a better understanding of the physical principles behind the procedure but also a significant increase in accuracy of their measurements and confidence in their colour determinations. Conclusions. Using an aesthetic evaluation protocol that translates teeth colour in a universal language for both practitioners as well as dental technicians has a significant impact in aesthetic dentistry.
Aspects of the biomechanical root canal treatment – step-back technique. In vitro study
Authors:   Departamentul Endodonţie, Facultatea de Medicină Dentară, Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti, Voiculeanu Monica , Suciu Ioana ,   Departamentul Endodonţie, Facultatea de Medicină Dentară, Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti, Dimitriu Bogdan ,   Departamentul Endodonţie, Facultatea de Medicină Dentară, Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti, Grigore Mihaela ,   Departamentul Endodonţie, Facultatea de Medicină Dentară, Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti
Published: September 2021

Evaluation of post-operative root canal shape have been performed using simulated root canals in resin blocks and magnification analysis (stereomicroscope) have been used for the study. The technique selected was stepback with conventional hand stainless steel instruments. The aim of studies on post-operative root canal shape is to evaluate the conicity, taper and flow and maintenance of original canal shape and to record the degree and frequency of straightening, apical transportation, ledging, zipping, teardrops, elbows. Ideal preparation forms for the root canals can be possible without any preparation errors with circular incorporation of the original canal cross section – if the technique starts with adequately precurved negotiating files. Preparation errors (zips, canal transportation, apical perforations, elbows, teardrops, etc) can occur mostly when stainless steel hand instruments (K-file) are used for moderate to severe curved of root canals, especially K-file with cutting tips and not prebent. Ideal preparation shape without any preparation errors could be a final shape and adequate shape even for conventional hand files and step-back technique. For the first area of step back technique, even for the begining, we can usually use various prebent stainless steel hand instruments for pathfinding. In many cases, conventional hand instruments produces adequate shapes for the root canals. For this final shape, is important to use adequately precurved negotiating files. Conventional stainless stell are rigid enough that thay should be precurved to match the curvature of the canal during instrumentation. Conventional hand instruments has two basic design, Kerr-file and Kerr-reamer. Kerr-file could be used to enlarge the canal with a longitudinal filing action. Kerr-reamer may used in a same fashion, but is much more flexible instrument than K-file. Noncutting tip follow the canal better than instruments with active tips – clinically usefull element.
Trigeminal neuralgia – dental pain of non-dental origin
Authors:   Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti, Mihăilescu Gabriela ,   Secţia Neurologie I, Spitalul Clinic Colentina, Bucureşti
Published: September 2021

Trigeminal neuralgia, as well as other orofacial types of pain, which make the differential diagnosis, can frequently be diagnosed as odontalgies, and stomatologic treatments are initiated, without relieving pain, and bringing the patients some complications. I will insist on the differential diagnosis of the different types of pain and on their specific treatments, in order to establish a better teamwork between stomatologists and neurologists, and a better outcome.
Difficult intubation at a patient with severe periodontitis having a biopsy of a larynx tumor – clinical case
Authors:   Institutul de Fonoaudiologie şi Chirurgie Funcţională ORL „Prof. Dr. Dorin Hociotă“, Bucureşti, Moscaliuc Bogdan , Zainea Viorel ,   Institutul de Fonoaudiologie şi Chirurgie Funcţională ORL „Prof. Dr. Dorin Hociotă“, Bucureşti,   Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti, Hainăroşie Răzvan ,   Institutul de Fonoaudiologie şi Chirurgie Funcţională ORL „Prof. Dr. Dorin Hociotă“, Bucureşti, Nisipaşu Cosmin ,   Universitatea „Titu Maiorescu“, Bucureşti
Published: September 2021

The purpose of this article is to present a situation in wich a dental problem can put the ATI doctor in difficulty and can have a negative impact on the postoperatory evolution. The case we are heaving is a patient with severe peridontitis wich complicates the intubation maneuver, being necessary to have temporary lingual retainers for the protection of the upper and inferior teeth. The intubation maneuver is awake oral fiberoptic laryngoscopy with good outcome.
Research on the clinical aspect of Angle Class II/1 malocclusions (accompanied by the bad habit of sucking the thumb)
Authors:   Disciplina de Ortodonţie, Facultatea de Medicină Dentară, Universitatea de Medicină şi Farmacie Craiova, Dascălu Ionela Teodora , Coleş Evantia ,   Disciplina de Morfologia Dinţilor şi Arcadelor Dentare, Tehnologia Protezelor Dentare,  Facultatea de Medicină Dentară, Universitatea de Medicină şi Farmacie Craiova, Amărăscu Marina Olimpia ,   Disciplina de Morfologia Dinţilor şi Arcadelor Dentare, Tehnologia Protezelor Dentare,  Facultatea de Medicină Dentară, Universitatea de Medicină şi Farmacie Craiova, Ţîrcă Tiberiu ,   Disciplina de Morfologia Dinţilor şi Arcadelor Dentare, Tehnologia Protezelor Dentare,  Facultatea de Medicină Dentară, Universitatea de Medicină şi Farmacie Craiova, Diaconu Oana Andreea ,   Disciplina de Odontoterapie-Endodonţie, Facultatea de Medicină Dentară, Universitatea de Medicină şi Farmacie Craiova, Stan Mihaela ,   Disciplina de Materiale Dentare, Facultatea de Medicină Dentară, Universitatea de Medicină şi Farmacie Craiova, Andrei Cristina Maria ,   Departamentul de Limbi Străine Aplicate, Universitatea din Craiova
Published: September 2021

Sucking the thumb is considered an inborn reflex. However, after the age of four (in case of emotional instability and anxiety) this reflex becomes a bad habit. This vicious habit is one of the most important etiological factors which determine the Angle Class II/1 malocclusion. The research relied on the analysis of the photos of schoolchildren aged 6 to 14 who admitted the persistence of this bad habit and also had Angle Class II/1 malocclusions. We analysed the photos of the face and of the exobuccal and endobuccal profiles. We have chosen two cases from the researched group to highlight the clinical aspects of Angle Class II/1 malocclusions. The patients maintained the bad habit of sucking the thumb which, accompanied by other etiological factors, led to a skeletal disequilibrium. Thus, many modifications may appear such as: upper jaw prognathism and lower jaw retrognathism with a sagittal inocclusion as well as changes of the physiognomy specific to Angle Class II/1 malocclusions. In the case of Angle Class II/1 malocclusions, the coexistence of hereditary and functional pathologic factors generally leads to skeletal and neuro-muscular modifications with aesthetic repercussions.
Recent contributions of medical anthropology to the study of social, economic and cultural aspects of tabacco and smoking
Authors:   Institutul de Antropologie „Francisc I. Rainer“ al Academiei Române, Bucureşti, Toma Valentin-Veron
Published: September 2021

Antropologia medicală, deşi mai puţin cunoscută, şi încă insuficient dezvoltată în România, 1 reprezintă un câmp de cunoaştere puternic la nivel in ternaţional, plin de resurse şi cu o evoluţie rapidă, de la care se aşteaptă mult în anii ce vor urma în ceea ce priveşte integrarea perspectivelor biologice şi culturale asupra sănătăţii, bolii şi vindecării, dar şi a umanităţii în ansamblul său (D. Joralemon, 1999).
TUMORAL MARKERS IN OVARIAN CANCER – A LITERATURE REVIEW
Authors:   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Bacalbasa Nicolae , Gireada Alexandra ,   “Carol Davila” Central Military Emergency Hospital, Bucharest, Balescu Irina ,   “Ponderas” Hospital, Bucharest
Published: September 2021

Ovarian cancer is one of the most lethal malignancies due to an aggressive biological behaviour of a tumor usually diagnosed in an advanced stage of the disease. Due to the fact that important differences in terms of survival have been observed between cases diagnosed in early stages when compared to those in FIGO stages III-IV, attention was focused on establishing which is the most appropriate laboratory diagnostic test which could help the clinician to diagnose and treat the disease in a less advanced stage. This is a literature review of the most frequently used tumor markers and scores used in ovarian cancer diagnostic and follow up.
Hostility, anger-in, rumination and aggressivity – major risk factors for coronary heart disease (CHD)
Authors:   NÄL Hospital, Trollhättan, Suedia, Chiţu Alexandru ,   Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti, Iamandescu Ioan Bradu ,   Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti
Published: September 2021

Friedman and Rosenman are highlighting behavioral type A as a major riskfactor for evolution worsening of myocardial infarction, was first and decisive step for clearly specifying the role of supportive psychosocial factors in etiopathogenesis of the coronary heart disease. Then, the reason that this type of behavior has been highlighted in other psychosomatic diseases (and even some healthy subjects) led to the need to fi nd other psychological variables – of personality, especially – associated with type A and convincing predictive value numerous epidemiological and experimental studies. In the last two decades has been it’s presence in some carriers of type A – which showed clinical and laboratory manifestations of coronary artery disease (including exploration angiographic coronary flow and computerized measurements) – this constant in varying degrees of complex traits emotional underpinning of increased aggression: hostility (cognitive and/or behavioral) – in particular internalized anger (anger-in) and ruminative anger. These variables have the correspondent psychological, somatic plan, vascular hyperreactivity to stress hormones (catecholamines and cortisol in particular) resulting in increased plasma cholesterol, myocardial oxygen consumption, the platelets aggregation etc. In essentially agressive featuters frequently expressed to the many distress “collected” by holders type A, pressed myocardium with pathophysiological changes specific for aggression.
Splenectomy – diagnostic and therapeutic option in haematological disorders
Authors:   Clinica ATI, Spitalul Universitar de Urgenţă, Bucureşti, Nica Adriana , Vlădăreanu Ana Maria ,   Clinica de Hematologie, Spitalul Universitar de Urgenţă, Bucureşti, Dumitru Ion ,   Clinica de Hematologie, Spitalul Universitar de Urgenţă, Bucureşti, Onisâi Minodora ,   Clinica de Hematologie, Spitalul Universitar de Urgenţă, Bucureşti
Published: September 2021

For hematologic disorders, splenectomy has a wide range of applications: diagnosis, palliative or curative. The most frequent indication is for red cell disorders: hereditary spherocytosis, autoimmune hemolytic anemia or thalassemia. For the platelet disorders, the greatest benefit is achieved in idiopathic thrombocytopenic purpura. In case of limfoproliferative disorders (leukemia, lymphoma), splenectomy plays a role in diagnosis, palliative care (lowering of tumor burden) and in some cases as a cure. In patients with hematologic disorders, splenectomy is associated with an elevated risk of infections that can be avoided with proper antibiotic prophylaxis and vaccination. Due to the expanding list of applications for splenectomy in hematologic disorder, it is necessary to establish a work protocol that covers all aspects and particularities of these disorders.
NUTRITION THERAPY IN THE TREATMENT OF OVERWEIGHT AND OBESE ADULTS WITH TYPE 2 DIABETES
Authors:   Department of Diabetes, Nutrition and Metabolic Diseases, Clinical Hospital Colentina, Bucharest, Vasilescu Razvan
Published: September 2021

It is well known the role of diet in the management of overweight and obese type 2 diabetic patients. Even a modest weight loss (5% to 10% of total body weight) is associated with improvements of cardiovascular risk factors. The traditional recommendations regarding the intake of macronutrients are: carbohydrate intake 45% to 65% of total energy, a total fat intake ≤ 35% of total energy (with reduction of saturated and trans fat intake and increase monounsaturated fatty acids intake) and protein intake 15% to 20% of total energy. The recent guidelines recommend increased flexibility in macronutrient composition. In this article I present different dietary patterns (such as low carbohydrate diets, high protein diets, low calorie diets, very low calorie diets and Mediterranean diet) used in the management of type 2 diabetic patients, their effects on short-term outcomes as well as on long-term outcomes. Energy restriction is required for weight loss. In short-term trials high-protein, low-carbohydrate diets are more favorable for weight loss than traditional high-carbohydrate, low-fat diets. Very important in weight loss and metabolic control are the adherence to a diet and pharmacotherapy. Recently probiotic and prebiotic have been proposed as a new treatment strategy.
Calcium role in digitalis acute poisoning – between myth and evidence-based medicine
Authors:   Disciplina Medicină internă – Urgenţe – Toxicologie, Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi, Rotariu Alexandra , Şorodoc Victoriţa ,   Disciplina Medicină internă – Urgenţe – Toxicologie, Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi, Bologa Cristina ,   Disciplina Medicină internă – Urgenţe – Toxicologie, Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi, Petriş Ovidiu ,   Disciplina Nursing, Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi, Şorodoc Laurenţiu ,   Disciplina Medicină internă – Urgenţe – Toxicologie, Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi, Lionte Cătălina ,   Disciplina Medicină internă – Urgenţe – Toxicologie, Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi
Published: September 2021

Digitalis poisoning is still frequently encountered in medical practice, either as acute or chronic overdosage. Toxic mechanism is represented by Na+/K+ ATP-ase blockade, followed by an increase in intracellular Na+ and hiperkalemia. Hiperkalemia increases mortality in digitalis poisoning, having a complementary effect to digitalis toxicity. Calcium salts are indicated for cardiac protection in hyperkalemia. Traditionlly, calcium was contraindicated in digitalis poisoning. A careful analisys of available studies demonstrates that calcium salts are useful in treatment of severe hyperkalemia, with electrocardiogram changes, associated with acute digitalis poisoning. Management issues for digitalis poisoning are presented in the end.
The role of family doctor in management of overweight and obese children and adolescents
Authors:   Disciplina Medicină de Familie, Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti, Iancu Mihaela Adela , Matei Dumitru ,   Disciplina Medicină de Familie, Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti, Bejan Gabriel Cristian ,   Disciplina Medicină de Familie, Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti
Published: September 2021

The children and adolescents obesity is one of the most important public health problems. The prevalence of obesity among children and adolescents is increasing in our country as in other European countries. Overweight and obese children are likely to stay obese into adulthood and more likely to develop cardiovascular diseases or diabetes. The majority of the overweight and obese children can be diagnosed, monitored and treated by the family doctors. Our intended purpose is to help family doctors with practical tools for the identification and management of overweight and obese children. The most recent recommendations regarding prevention of childhood obesity focus on increased exercise and improved diet to prevent childhood obesity. Intensive lifestyle modification remains the primary treatment of the children obesity. The family doctors must know how to prevent the development of overweight and obese complications.
OVARIAN METASTATIC TUMORS – A LITERATURE REVIEW
Authors:   „Carol Davila“ University of Medicine and Pharmacy, Bucharest, Bacalbasa N. , Traistaru A. ,   Elias University Emergency Hospital, Bucharest, Balescu I. ,   „Ponderas“ Hospital, Bucharest
Published: September 2021

Ovarian metastatic tumors represents up to 10% of all ovarian malignancies. The most encountered tumors which may give birth to ovarian cancer are those originating from the gastric tube; however, other malignancies such as breast, cervix, lung or even skin may be associated with ovarian metastatic tumors. This is a literature review of the most frequently seen ovarian metastatic tumors.
Minimally invasive treatment for Hirschsprung disease
Authors:   Spitalul Clinic de Urgenţă pentru Copii „Grigore Alexandrescu“, Bucureşti, Tudorache Simona-Gabriela ,   Universitatea de Medicină şi Farmacie „Carol Davila“ Bucureşti, Negoiţescu Felix ,   Spitalul Clinic de Urgenţă pentru Copii „Grigore Alexandrescu“, Bucureşti,   Universitatea de Medicină şi Farmacie „Carol Davila“ Bucureşti, Niculescu Laura ,   Spitalul Clinic de Urgenţă pentru Copii „Grigore Alexandrescu“, Bucureşti,   Universitatea de Medicină şi Farmacie „Carol Davila“ Bucureşti
Published: September 2021

Introduction. Harold Hirschsprung, a physician at Queen Louise Children’s Hospital of Copenhagen, first described the disease that now bears his name, at the Pediatric Congress of Berlin in 1886. Since then there have been countless debates on the optimal surgical approach. This paper aims both to recap the main classical surgical techniques: Swenson, Duhamel and Soave, but the main focus is on minimally invasive techniques. Surgical techniques. In the last 25 years, the treatment for Hirschsprung disease has progressed. If classically the preferred treatment was in 2-3 stages, now the definitive intervention is per primam in most cases, thus avoiding the morbidity associated with stomas. In 1995, Georgeson describes the minimally invasive approach using laparoscopy, and then in 1998, De la Torre et al, describes the first transanal endorectal pull-through (TERPT), unattended laparoscopically. Discussions. The initial discussions were linked to comparing processes in a single stage with ones in 2 or 3 stages, finding similar results, it is now a question of comparing open techniques with minimally invasive and even minimally invasive techniques with each other, endeavoring to establish whether laparoscopically assisted approach is needed or if the transanal one is enough. Conclusion. Usually shorter forms of Hirschsprung disease are treated strictly using the transanal technique, for the forms involving the left and transverse colon laparoscopically assisted transanal pull-through is used, while for the ascending colon and for the total aganglionosis the laparoscopically assisted Duhamel procedure is preferred.
Diagnosis and treatment in premature births
Authors:   Spitalul Clinic „Sfântul Ioan“, Maternitatea Bucur, Bucureşti, Said Aboayesh , Nanu Dimitrie ,   Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti
Published: September 2021

Definition. Preterm birth means that birth occurs between 20 and 37 weeks of amenorrhea complete. (ACOG – July 2014) In Romania, the declaration of pregnancy is made starting with 24 weeks of gestation. Outstanding progresses in the recovery of newborns weighing less than 1,000 grams (the US and Japan recovered newborns weighing 500 g and less) allowed international forums reconsider criteria for definition of prematurity (see abortion classifications). For performant neonatal departments, the presence of signs of life (beating heart, pulsation of the umbilical cord, muscle contracture to external stimuli) are sufficient to use resuscitation and recovering the product of conception.
Difficulties of diagnosis and treatment in a case of malignant melanoma
Authors:   Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti, Petrescu Marieta ,   Spitalul Universitar de Urgenţă Bucureşti, Alexandru Adrian ,   Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti,   Spitalul Universitar de Urgenţă Bucureşti, Benga Andreea ,   Spitalul Universitar de Urgenţă Militar Central „Dr. Carol Davila“, Bucureşti, Dumitrescu Doina ,   Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti
Published: September 2021

Malignant melanoma is a rare form of skin cancer, which is only about 3-4% of all skin cancers, but results in a mortality rate up to 65-70%. The vast majority of melanomas are diagnosed in stage 0, I and II, but there were cases when the primary diagnosis of malignant melanoma patients was put directly in stage IV metastatic disseminated lymph nodes, lung, liver, spleen, bone, brain. In the case of a patient with metastatic melanoma, poor biological condition limits the diagnostic and therapeutic possibilities.
Predictive factors of outcome in assisted reproductive technologies
Authors:   Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti, Coricovac Anca ,   Clinica Medicală Gynera, Bucureşti, Nanu Dimitrie ,   Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti, Dracea Laura ,   Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti,   Clinica Medicală Gynera, Bucureşti
Published: September 2021

Objectives. Study of predictive factors of outcome in assisted reproductive technologies. Material and methods. The retrospective study on a sample that contains information about 1,121 cycles of embryo transfer (ET) from oocytes and sperm autologous procedures. To quantify the relationship between indicators of success and influence factors, a multivariate analysis were used for factors affecting probability of pregnancy (biochemical or clinical) with in vitro fertilization in relation with 14 independent variables (factorial explanatory). Results. Variables with positive influence correlated with biochemical or clinical pregnancy were identified as: type of medication for ovarian stimulation, age of embryo at the day of transfer, number of days of stimulation, number of retrieved oocytes, female age. Conclusion. Study of risk factors and their influence on the success of assisted reproduction technologies may offer new information and could change practice in the field of in vitro fertilization (IVF). Female age, number of days of stimulation and number of retrieved oocytes are predictors for the chance of pregnancy in IVF treatments. More extensive studies are needed, especially studies that focus on the analysis of factors related to embryo quality as predictors of pregnancy in IVF.
LYMPHANGIOMA-LIKE KAPOSI SARCOMA: CHALLENGES IN DIFFERENTIAL DIAGNOSIS
Authors:   Dermatology Department, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Georgescu S.R. , Limbau A.M. ,   Dermatology Department, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Tampa M. ,   Dermatology Department, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Tanasescu M.D. ,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Zurac S. ,   “Colentina” Clinical Hospital, Bucharest, Popa M.I. ,   “Carol Davila” University of Medicine and Pharmacy, Bucharest
Published: September 2021

Background. Kaposi’s sarcoma (KS) is a multifocal vascular neoplasia with uncertain histogenesis, characterized by angioproliferative multifocal tumors affecting mainly the skin. The “lymphangioma-like” or “bullous KS” variant is a rare morphologic expression of KS, accounting for less than 5% of all cases and appearing among all KS epidemiological subtype. This review provides a comprehensive overview of clinical and pathological characteristics of patients with lymphangioma-like Kaposi’s sarcoma LLKS. Methods. We included 93 patients with Kaposi sarcoma, aged between 36 and 90 years; diagnosis was made as a result of the histopathological examination. The surgical excision samples were fixed in 10% buffered formalin, paraffin embedded and stained with Hematoxylin-Eosin for histopathological examination. Immunohistochemical staining was performed using the following antibodies: CD34, CD31, actin, myoglobin, desmin, cytokeratin and vimentin. Results. The histological features of LLKS vary considerably from the traditional KS, classic KS areas have been absent from some lymphangioma-like KS. Most of the patients were diagnosed in nodular stage and confirmed by positive immunohistochemical staining. Clinically, each patient presented with violaceous patches, papules or plaques; some of the patients presented with bullous lesions. All tumour cells, including those associated with LLKS foci, showed a strong and diffuse reactivity for anti-HHV-8 LNA-1and anti-CD34. Conclusions. Differential diagnosis of lymphangioma-like Kaposi’s sarcoma LLKS with other vascular tumors may be very difficult and a detailed histologic study in combination with immunohistochemistry, such as staining for HHV-8 latent nuclear antigen, is essential for correctly diagnosing lymphangioma-like KS.
GASTRIC CANCER TUMOR MARKERS
Authors:   “Carol Davila” Central Military Emergency Hospital, Bucharest, Romania, Gireada Alexandra , Balescu Irina ,   “Ponderas” Hospital, Bucharest, Romania, Bacalbasa Nicolae ,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
Published: September 2021

Gastric cancer remains an aggressive malignancy responsible for a high number of deaths annually. An important method used in order to determine the response to treatment, follow-up and detection of recurrence in association with imagistic examinations remains laboratory determination of tumor markers. The most common used tumor markers in patients diagnosed with gastric cancer are CA 72-4, CEA, CA 19-9.
Essential tremor
Authors:   Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti, Mihăilescu Gabriela ,   Secţia Neurologie I, Spitalul Clinic „Colentina“, Bucureşti
Published: September 2021

Essential tremor is a frequent disease, but rather often under-diagnosed, due to the fact that the patients with mild essential tremor don’t visit the neurologist, or due to some confusion in establishing the diagnosis in advanced stages of the disease. The clinical diagnosis is the most important, and is sustained today by imaging techniques such as Datscan using 123I-Ioflupane, used in the differential diagnosis between essential tremor and Parkinsonian syndromes. The precise and early diagnosis permit the specific, customized symptomatic treatment, taking care of al the particularities of every patient, and in case of no-response to medical treatment, neurosurgical methods are available, some of them very recent, some still in clinical trials, as well as the genetic studies in order to establish the etiology of the most frequent disease in the field of movement disorders.
Clinical and functional evaluation in patients with upper limb disability following traumatic peripheral nerve injury. Part II
Authors:   Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti, Moise (Constantinovici) Mariana-Isabela , Nica Adriana Sarah ,   Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti
Published: September 2021

Background. Current studies regarding the consequences of upper limb traumatic peripheral nerve injuries adresses both sensory-motor dysfunction and functioning, disability and pain issues. Aims. This article presents an overview of the biomedical literature regarding the available assessment methodologies and outcome measures used in research and clinical practice for the evaluation of upper limb function in the therapeutic management of posttraumatic upper limb peripheral nerve injuries and disability and their impact on patient’s functioning, health and quality of life. Design. Systematic review of the international biomedical literature. Methods. We used PubMedCentral database searches (PMC) of the last 10 years published literature. There were excluded scientific abstracts and articles that did not match to our search criteria, such as studies on brachial plexus injury, diabetic neuropathy, upper limb neurologic impairment due to Stroke, TBI or SCI, etc. Results and discussion. We selected 20 studies from the identified articles. We presented an overview of the main assessment methodologies and functional parameters investigated in these studies.
Pertanggungjawaban Lingkungan International Financial Institutions: Tinjauan Hukum Putusan Kasus JAM terkait Pencemaran Lingkungan Proyek Pembangunan PLTU di Gujarat India
Authors: Setiaji Arfian
Published: September 2021

Dengan kekuatan modal yang besar, pengaruh International Financial Institutions (IFIs) dalam setiap proyek pembangunan di banyak negara berkembang tidak dapat dianggap remeh. Meskipun dianggap memiliki modal dan pengaruh yang besar, beberapa IFIs seperti World Bank Group kerap dituding sebagai pihak yang bertanggung jawab atas dampak lingkungan yang muncul karena proyek yang didanainya. Fakta bahwa beberapa IFIs besar seperti World Bank Group berkantor pusat di Amerika Serikat menjadi alasan artikel ini untuk mengeksplorasi isu pertanggungjawaban lingkungan IFIs dari kasus hukum di Amerika Serikat yang belum lama ini mendapat banyak sorotan dari berbagai pihak internasional. Artikel ini membahas aspek-aspek pertanggungjawaban lingkungan IFIs dengan melakukan tinjauan hukum terhadap putusan kasus JAM terkait pencemaran lingkungan proyek pembangunan pembangkit listrik batu bara di Gujarat, India yang didanai oleh International Finance Corporation.
Membaca Arah Perubahan Kehutanan Pasca-terbitnya Undang-Undang Cipta Kerja
Authors: Nugroho Ardiyanto wahyu
Published: September 2021

Tujuan utama penerbitan Undang-Undang Nomor 11 Tahun 2020 tentang Cipta Kerja (UUCK) adalah menciptakan lapangan kerja baru bagi rakyat Indonesia, termasuk di sektor kehutanan. Total 79 undang-undang direvisi dalam UUCK untuk mempercepat perijinan investasi, termasuk UU No. 41 Tahun 1999 tentang Kehutanan. Hal ini dilakukan untuk memangkas birokrasi, mempercepat investasi dan meningkatkan ekonomi. Akan tetapi, saat ini masih terdapat sejumlah permasalahan besar pada pengelolaan hutan di Indonesia, seperti tingginya laju deforestasi, penyerobotan kawasan hutan, illegal logging dan kebakaran hutan. Dengan demikian, merubah aturan pengelolaan hutan untuk mengakomodasi kepentingan ekonomi sangat beresiko merusak hutan. Penelitian ini dilakukan untuk mengetahui dampak yang kemungkinan bisa terjadi akibat perubahan aturan dasar pengelolaan hutan di Indonesia, pasca-terbitnya UUCK. Hasil penelitian menunjukkan bahwa UUCK akan berdampak pada perubahan tata kelola hutan lindung dan produksi, yaitu kawasan hutan yang dikelola oleh pemerintah provinsi. Jika dilakukan dengan baik, UUCK berpotensi memperbaiki tata kelola kedua jenis kawasan tersebut.
USE OF PORTFOLIO ANALYSIS TOOLS TO BALANCE THE INSURANCE PORTFOLIO
Authors:   Plekhanov Russian University of Economics, EGOROVA EKATERINA S.
Published: September 2021

The research work reveals the essence of portfolio analysis and its main tools. The possibility of using portfolio analysis tools for the insurance industry is substantiated. As part of the study, a matrix is formed for assessing the balance of the insurance portfolio in accordance with the most important criteria in the field of insurance.
IMPROVING THE ENERGY EFFICIENCY OF SMART CITIES DURING THE COVID-19 PANDEMIC
Authors:   Moscow State Aviation Institute (National Research University), PUSHKAREV MAKSIM D. , PROKOFIEV DMITRY A. ,   Moscow State Aviation Institute (National Research University)
Published: September 2021

Smart city technologies make the functioning of urban infrastructure more efficient, and the lives of citizens more comfortable and safe. During the COVID-19 pandemic, they were very popular, and this could not but affect the energy efficiency of high-tech megacities around the world. This article examines the impact of the COVID-19 pandemic on smart cities, and also offers a solution to the problem of energy efficiency of smart cities.