bluuebunny/crossref_metadata_2025 huggingface dataset:
Rapid Improvement in Cardiac Damage Predicts Better Prognosis After Transcatheter Aortic Valve Replacement
Authors: Lee Hao-Wei , Chin Chih-Hui , Chou Po-chin , Chang Chia-Hsiu , Tsai Chiu-Ling , Huang Chi-Hung
Published: January 2025

Background: A staging system based on cardiac damage for severe aortic stenosis (AS) has been validated for prognosis prediction following transcatheter aortic valve replacement (TAVR). Our study aims to investigate whether TAVR can lead to changes in cardiac damage shortly after the procedure and how these changes impact prognosis. Method: Patients in this retrospective cohort study were classified into five stages (0–4) before TAVR based on the echocardiographic findings of cardiac damage. The closest echocardiogram after TAVR was used for restaging cardiac damage. The primary composite outcome was all-cause mortality or hospitalization due to heart failure (HF). Results: A total of 64 patients were enrolled (53.1% male, mean age 81.7 ± 7.7 years). Within a mean interval of 4 days (interquartile range = 3 to 7 days) after TAVR, cardiac damage improved in 25.0% of patients, while it worsened in 20.3%. During a median follow-up of 2.5 ± 1.9 years, 34.4% of patients met the primary endpoint, which included 16 deaths and 6 HF hospitalizations. Cox regression analysis revealed that improvement in cardiac damage correlated with a lower risk of composite death or HF hospitalization (HR: 0.095; 95% CI: 0.014–0.627; p = 0.015). Conclusions: TAVR can lead to changes in cardiac damage over a short period in patients with severe AS, and rapid improvement in cardiac damage after TAVR is associated with a better prognosis.
Emotional and Behavioural Adjustment in Children and Adolescents with Short Stature vs. Their Normal-Statured Peers
Authors: Guerrini Usubini Anna , Marazzi Nicoletta , Abbruzzese Laura , Tringali Gabriella , De Micheli Roberta , Castelnuovo Gianluca , Sartorio Alessandro
Published: January 2025

Background/Objectives: the aim of the current cross-sectional study is to explore and compare the emotional and behavioural conditions of children and adolescents with short stature (i.e., familial short stature and constitutional delay of growth), idiopathic growth hormone deficiency (GHD), and normal height. Methods: Twenty-nine participants (15 males, 14 females; mean age ± standard deviation (SD) = 11.2 ± 1.96 years) with short stature (height standard deviation score (SDS): −2.10 ± 0.57), 10 age-matched participants (4 males, 6 females; mean age ± SD = 10.9 ± 2.35 years) with growth hormone deficiency (GHD; height SDS: −2.44 ± 0.29), and 36 age-matched participants (19 males, 17 females; mean age ± SD = 11.3 ± 1.93 years) with normal stature (height SDS: 0.56 ± 0.78) were admitted to this study. Psychological distress was evaluated using the Depression Anxiety and Stress Scale (DASS-21), and emotional and behavioural problems using the Child Behaviour Checklist for Children (CBCL) and the Strengths and Difficulties Questionnaire (SDQ). Results: Participants with GHD exhibited higher levels of the “withdrawn/depressed subscale” score of CBCL (H = 7.794, df = 2, p = 0.020), compared to their peers with normal height, while no significant differences were observed between participants with short stature and those with normal stature. Normal-statured participants reported higher levels of the “conduct problems” subscale score (H = 10.421, df = 2, p = 0.005) and the “rule-breaking behaviour” subscale score of CBCL (H = 10.358, df = 2, p = 0.006) compared to both short-statured groups. No significant differences among the three subgroups were found in the DASS-21 and SDQ scores questionnaires, suggesting the lack of short stature-dependent effects on psychological distress and emotional and behavioural adjustment. Conclusions: Although participants with GHD exhibited higher levels of the “withdrawn/depressed subscale” score of CBCL (H = 7.794, df = 2, p = 0.020) compared to their peers with normal height, participants with short stature did not experience the same problems. Although short-statured participants had lower levels of “conduct problems” and “rule-breaking behaviours” scores than their normal-statured peers, the psychological distress and emotional and behavioural adjustment were not affected by short stature, being comparable to those recorded in normal-statured participants.
Erosion–Seepage System (ESS) for Flow-Induced Soil Erosion Rate with Seepage
Authors: Zhang Yuhuan , Cui Lin , Jeng Dong-Sheng , Wang Zheng , Zhai Hualing
Published: January 2025

Critical shear stress and erosion rate are two key factors for the prediction of the incipient motion of sediment and the transport of sediment. Seabed seepage can significantly alter the pore pressure gradient within the soil and the hydrodynamics around the surface of the seabed, further affecting erosion processes. Previous studies attempted to theoretically clarify the effect of the seepage force on sediment incipient motion. In this study, a newly designed erosion–seepage system (ESS) that considers the effect of seepage under steady or oscillatory flow is used to simulate the erosion process. Through the designed ESS, the erosion height per unit time was measured directly on the Yellow River sand, and the upward seepage force was applied at the bottom of the soil sample in the process. Then, the relationship between the erosion rate and seepage was established.The experimental results show that upward seepage reduces the critical shear stress of the sand bed and increases the erosion rate of the soils under both steady flow and oscillatory flow conditions. The erosion coefficients in the erosion models decrease with increasing seepage gradient. The effect of seepage on erosion is more obvious when the flow velocity of the steady stream is large, while the effect of seepage on erosion is relatively small under the oscillatory state with a shorter period. However, when violent erosion of soil samples occurs, seepage under both flow conditions greatly increases the erosion rate.
Synthesis and Insecticidal/Fungicidal Activities of Triazone Derivatives Containing Acylhydrazone Moieties
Authors: Cui Peipei , Yang Yan
Published: January 2025

A series of novel triazone derivatives containing aldehyde hydrazone or ketone hydrazone moieties were designed, synthesized and their biological activities were investigated against Aphis craccivora, Culex pipiens pallens, Helicoverpa armigera, Ostrinia nubilalis, Mythimna separata and 14 Kinds of fungi. Most of the aldehyde hydrazone exhibited excellent insecticidal activities against A. craccivora. In particular, the aphicidal activities of compounds 3t (35%) and 3w (30%) were equivalent to pymetrozine (30%) at 5 mg/kg. The aphicidal activities of derivatives 3p, 3u, 3y, 5g, 5i, 5l, 5q and 5u against C. pipiens pallens were higher than that of pymetrozine. Compound 3u (100%) exhibited good larvicidal activities against C. pipiens pallens at 0.25 mg/kg. Most derivatives exhibited broad-spectrum fungicidal activities against 14 kinds of plant fungi at 50 mg/kg. Thirty-nine compounds exhibited a more than 50% inhibition rate against Physalospora piricola. Compounds 3h, 3t and 3w were expected to be the leading structure for the development of new triazone insecticides agents.
Mechanistic Insights into the Anticancer Potential of Methoxyflavones Analogs: A Review
Authors: Aidiel Mohammad , Abdul Mutalib Maisarah , Ramasamy Rajesh , Nik Ramli Nik Nasihah , Tang Shirley Gee Hoon , Adam Siti Hajar
Published: January 2025

2-phenylchromen-4-one, commonly known as flavone, plays multifaceted roles in biological response that can be abundantly present in natural sources. The methoxy group in naturally occurring flavones promotes cytotoxic activity in various cancer cell lines by targeting protein markers, in facilitating ligand–protein binding mechanisms and activating cascading downstream signaling pathways leading to cell death. However, the lipophilic nature of these analogs is a key concern as it impacts drug membrane transfer. While lipophilicity is crucial for drug efficacy, the excessive lipophilic effects in flavonoids can reduce water solubility and hinder drug transport to target sites. Recent in vitro studies suggest that the incorporation of polar hydroxyl groups which can form hydrogen bonds and stabilize free radicals may help overcome the challenges associated with methoxy groups while maintaining their essential lipophilic properties. Naturally coexisting with methoxyflavones, this review explores the synergistic role of hydroxy and methoxy moieties through hydrogen bonding capacity in maximizing cytotoxicity against cancer cell lines. The physicochemical analysis revealed the potential intramolecular interaction and favorable electron delocalization region between both moieties to improve cytotoxicity levels. Together, the analysis provides a useful strategy for the structure–activity relationship (SAR) of flavonoid analogs in distinct protein markers, suggesting optimal functional group positioning to achieve balanced lipophilicity, effective hydrogen bonding, and simultaneously minimized steric hindrance in targeting specific cancer cell types.
Correction: Khavinson et al. Neuroprotective Effects of Tripeptides—Epigenetic Regulators in Mouse Model of Alzheimer’s Disease. Pharmaceuticals 2021, 14, 515
Authors: Khavinson Vladimir , Ilina Anastasiia , Kraskovskaya Nina , Linkova Natalia , Kolchina Nina , Mironova Ekaterina , Erofeev Alexander , Petukhov Michael
Published: January 2025

In the original publication [...]
Advances in Deflocculant Utilisation in Sustainable Refractory Concrete with Refractory Waste
Authors: Pranckevičienė Jolanta , Pundienė Ina
Published: January 2025

In the last 10–15 years, the use of waste refractory materials has significantly increased because it is not economically justified to transport such expensive materials to landfills. This work compared the physical and mechanical properties of refractory concrete samples with those of individual deflocculants—polycarboxilate, sodium tripolyphosphate, and a deflocculant mixture. Three refractory concrete compositions with individual deflocculants and a deflocculant mix were created to choose the best main properties of refractory concrete. Five compositions of refractory concrete specimens were created by partial replacement of chamotte aggregate (CA) by refractory concrete waste (RCW) (100, 75, 50, and 25%). Exothermal profile, structure development and spread were determined for fresh refractory concrete pastes. It was found that with an increase in CA replacement level to RCW, the EXO maximum temperature, spread and structure evolution speed decreases. SEM and porosity tests confirmed density, compressive strength results and structural parameters. The study shows that RCW replacement slows the hydration process, particularly at replacement levels above 33%. However, replacement levels of up to 25% improve compressive strength by 13% due to the additional amount of cement minerals in RCW aggregates, which can participate in the hydration process, making it a viable option for applications where enhanced durability is required, such as in non-critical zones of industrial refractory linings.
Neurotropic Tick-Borne Flavivirus in Alpine Chamois (Rupicapra rupicapra rupicapra), Austria, 2017, Italy, 2023
Authors: Nowotny Norbert , Mandola Maria Lucia , Monne Isabella , Bagó Zoltán , Nogarol Chiara , Fusaro Alice , Dimmel Katharina , Moroni Barbara , Guardone Lisa , Kolodziejek Jolanta , Palumbo Elisa , Stanclova Gabriela , Steinrigl Adi , Fidler Gabriele , Bertasio Cristina , Bertoletti Irene , Bianchi Alessandro , Calzolari Mattia , Prati Paola , Vicari Nadia , Salomoni Angela , Priore Maria Francesca , Gobbo Federica , Garcia-Vozmediano Aitor , Loney Tom , Abou Tayoun Ahmad , Alsheikh-Ali Alawi , De Benedictis Paola , Camp Jeremy V. , Hubalek Zdenek , Rudolf Ivo , Lelli Davide , Moreno Ana
Published: January 2025

The European subtype of tick-borne encephalitis virus (TBEV-Eur; species Orthoflavivirus encephalitidis, family Flaviviridae) was the only tick-borne flavivirus present in central Europe known to cause neurologic disease in humans and several animal species. Here, we report a tick-borne flavivirus isolated from Alpine chamois (Rupicapra rupicapra rupicapra) with encephalitis and attached ticks, present over a wide area in the Alps. Cases were detected in 2017 in Salzburg, Austria, and 2023 in Lombardy and Piedmont, Italy. The virus strains exhibit 94.8–97.3% nucleotide identities to each other and are more closely related to Louping ill viruses (LIV; Orthoflavivirus loupingi; 90–92% identities) than to TBEV-Eur (less than 88%). The chamois-derived virus strains, tentatively termed “Alpine chamois encephalitis virus”, form a well-supported independent genetic clade with Spanish goat encephalitis virus, clearly separated from other LIV. This supports its designation as a new virus subtype with the proposed shared taxonomic name “Spanish goat and Alpine chamois encephalitis virus subtype” within the species Orthoflavivirus loupingi. The zoonotic potential of this newly identified virus subtype as well as its host range in other animal species including farm animals needs to be further investigated.
Ensuring the epidemiological safety of a medical organization during the period of an increase in the incidence of influenza and acute respiratory viral infections
Authors:   N.I. Pirogov National Medical and Surgical Center of the Ministry of Health of the Russian Federation, Central Research Institute of Epidemiology of Rospotrebnadzor, N.F. Gamaleya National Research Center of Epidemiology and Microbiology of the Ministry of Health of the Russian Federation, Moscow, Russia, Orlova O. A. , Rusakova E. V. ,   N.F. Gamaleya National Research Center of Epidemiology and Microbiology of the Ministry of Health of the Russian Federation, Moscow, Russia, Semenenko T. A. ,   N.F. Gamaleya National Research Center of Epidemiology and Microbiology of the Ministry of Health of the Russian Federation, Sechenov First Moscow State Medical Universit y of the Ministry of Health of the Russian Federation (Sechenov University),Moscow, Russia
Published: January 2025

Every year, acute respiratory viral infections (ARVI) hold leading positions in terms
of morbidity and economic damage both in the world and in the Russian Federation. A medical
organization requires the use of not individual preventive measures, but an integrated
approach. Objective: to optimize a set of measures aimed at ensuring epidemiological safety
during the period of increased incidence of influenza and acute respiratory viral infections.
To achieve this goal, a set of measures was adapted for use in medical organizations based
on current regulatory documents on the prevention of influenza and acute respiratory viral
infections. The work was carried out at the inpatient department of a large multidisciplinary
medical center for the period 2020–2024. The developed set of measures included three areas:
organizational, preventive and anti-epidemic. Organizational measures were carried out
both during the period of no increase in the incidence of influenza and acute respiratory viral
infections and during the period of increased incidence. Preventive measures carried out in
the hospital are aimed at minimizing the possibility of introducing the infectious agent from
outside, eliminating infection directly in the hospital and preventing the removal of the pathogen
outside the hospital. The use of the developed set of measures led to a decrease in the
number of introductions of ARVI and flu pathogens into the hospital of a medical organization,
and the absence of group morbidity.
Amaranthus pakai (Amaranthaceae), a New Critically Endangered Species from the Hawaiian Islands
Authors: Faccenda Kevin , Bayón Néstor David , Waselkov Katherine , Hobdy† Robert W.
Published: January 2025

Amaranthus pakai Faccenda & N. Bayón (Amaranthaceae), a new Hawaiian endemic species from the main islands, is described. It is most probably closely related to A. brownii Cristoph. & Caum, an extinct species from Nihoa Island. It also morphologically resembles A. interruptus R. Br. and A. viridis L. Amaranthus pakai differs from these species in its leaves with elliptical lamina, and pistillate flowers with three widely spathulate sepals, which are longer than the fruits. The first collections date back to the 19th century and suggest that this species was formerly rather widespread across the main Hawaiian Islands, but the population probably crashed during the 1800s. However, these early specimens were misidentified until recently. Amaranthus pakai was last seen in the wild in 2014 and, following its assessment against the IUCN criteria, is considered Critically Endangered, as only 30 to 40 plants were seen at that time.
The Meta-Analysis of Dysphagia in the Elderly: A Review of Studies Published in Korean Journals from 2012 to 2024
Authors:   Society of Occupational Therapy for the Aged and Dementia, Lee Yun-Jeong , Yang Yeong-Ae
Published: January 2025

Objective : The purpose of the study is to explore future research directions by meta-analyzing the research objectives, research methods, and distribution of research fields established in domestic studies related to swallowing disorders in the elderly.
Methods : This is a meta-analysis that references the research of Jung (2024) based on the research methodology of Kitchenham (2004) and the research of Lee (2023) and Creswell and Creswell (2017).
Results : Compared to the early days, research on swallowing disorders in the elderly is pursuing research at a developmental level, and quantitative research methods account for a high proportion. The field that deals with swallowing disorders in the elderly was initially nursing, but has now shifted toward rehabilitation and occupational therapy.
Conclusion : Future research should advance case studies grounded in foundational data, addressing the current emphasis on quantitative research methodologies. Efforts within the academic community are essential to balance this trend and broaden research perspectives. Additionally, for studies on dysphagia in older adults to achieve a more integrative discourse, it is crucial to adopt an interdisciplinary approach that incorporates new perspectives from various academic fields. This approach will enhance the field’s capacity to address the complexity of dysphagia through a convergent and multidimensional lens.
Effects of Perception of Good death and Moral Sensitivity on Attitudes Toward Withdrawal of Life-sustaining Treatment among Nursing Students
Authors:   Society of Occupational Therapy for the Aged and Dementia, Cho Eun-A
Published: January 2025

Objective : The purpose of this study is to identify the factors influencing nursing students' attitudes toward withdrawal of life-sustaining treatment, based on their perceptions of a good death and moral sensitivity.
Methods : The study participants consisted of 175 nursing students from three universities located in G city. The collected data were analyzed using SPSS Statistics 24.0.
Results : The strongest predictor of attitudes toward the withdrawal of life-sustaining treatment was moral sensitivity (β=.23, p=.004), followed by the perception of a good death (β=.16, p=.045), and the model explained 10.4% of the variance.
Conclusion : It is suggested to enhance the curriculum and develop educational programs to improve moral sensitivity and the perception of a good death, in order to foster a positive attitudes toward withdrawal of life-sustaining treatment among nursing students.
PERLINDUNGAN HUKUM TERHADAP DATA PRIBADI PENGGUNA LAYANAN PINJAMAN ONLINE ILEGAL
Authors: Dinda Putri Oktaviansjah  , Beryl Nahdah Gunardi  , Amanda Nadya Oktavia  , Variza Octifanny Rahmadianti  , Shafa Safira Diana
Published: January 2025

Globalisasi membuat perkembangan teknologi semakin cepat, begitu pula di bidang perekonomian. Salah satunya dalam bertransaksi pinjam-meminjam yang saat ini telah tersedia melalui media elektronik berbasis online, namun pada pelaksanaannya sering kali terdapat laporan atas penyalahgunaan data diri pribadi konsumen yang dilakukan oleh perusahaan yang tidak terdaftar dalam Otoritas Jasa Keuangan (OJK). Berdasarkan permasalahan hukum tersebut, penulis menggunakan metode penelitian yuridis-normatif dengan menggunakan jenis pendekatan undang-undang (statute approach)   untuk menjawab mengenai perlindungan hukum terhadap data pribadi pengguna layanan pinjaman online ilegal ditinjau dari Undang-Undang Informasi dan Transaksi Elektronik serta Undang-Undang Perlindungan Konsumen. Hasil dari penelitian ini adalah telah ditemukan beberapa kasus di lapangan yang terbukti sebagai penyalahgunaan data diri pribadi dari konsumen pinjaman online ilegal. Penyalahgunaan data diri pribadi yang dilakukan perusahaan pinjaman online ilegal dapat didasarkan pada Undang-Undang Informasi dan Transaksi Elektronik dan Undang-Undang Perlindungan Konsumen
Pertanggungjawaban Oknum Polisi yang Melakukan Penganiayaan Terhadap Tersangka dalam Proses Penyidikan (Studi Kasus Putusan Nomor 7/PID/2016/PT BBL)
Authors: Mufti Muhammad Wildan
Published: January 2025

Penelitian ini menganalisis pertanggungjawaban oknum polisi yang melakukan penganiayaan terhadap tersangka dalam proses penyidikan, dengan studi kasus pada putusan nomor 7/PID/2016/PT BBL. Kasus ini melibatkan empat anggota polisi dari Satuan Narkoba Polres Bangka yang melakukan kekerasan terhadap seorang tersangka narkoba hingga menyebabkan kematiannya. Tindakan tersebut melanggar hak asasi manusia dan merusak reputasi kepolisian. Penelitian ini bertujuan untuk menganalisis perlindungan hukum bagi tersangka yang menjadi korban kekerasan oleh polisi, serta mengidentifikasi penegakan hukum terhadap polisi yang melakukan kekerasan dalam proses penyidikan. Metode yuridis normatif digunakan dengan pendekatan statute dan conceptual. Hasil menunjukkan bahwa meskipun terdapat aturan yang melindungi hak-hak tersangka, praktik kekerasan oleh polisi masih terjadi, dan penegakan hukum terhadap pelaku kekerasan seringkali tidak konsisten. Diperlukan peningkatan pelatihan hak asasi manusia bagi polisi, penguatan mekanisme pengawasan, dan partisipasi aktif masyarakat dalam melaporkan kekerasan. Langkah-langkah ini diharapkan dapat meningkatkan integritas dan kepercayaan masyarakat terhadap penegakan hukum di Indonesia.
Maraknya Fenomena Hate Comment di Kalangan Remaja Indonesia dalam Bermedia Sosial
Authors: Zain Abyan , Safa Mutiara Ayu , Anggita Fitriyani Jeanny , Cynthia Agnes , Tarisa Sabrina Fadiah , Falevi Yunizar , Amelia Sandra , Gilang Bhaswara Nadhif , Setya Abrilrizky Haryadian , Putri Eriana Nadhifa , Dwiastuti Winda , Syahrul Ramadhan Muhammad , Subhandi Bakhtiar Handar
Published: January 2025

Terlepas dari banyak kemudahan yang dirasakan tentu ada juga dampak buruk dari pesatnya perkembangan teknologi saat ini,  maraknya hate comment yang terjadi di media sosial merupakan bentuk dampak buruk dari perkembangan teknologi saat ini. Jurnal dibuat dengan tujuan untuk mengkaji tentang arti dari hate comment serta meneliti tentang peraturan-peraturan di Indonesia yang mengatur tentang hate comment, dan untuk lebih memahami mengenai dampak dari hate comment sehingga maraknya hate comment dapat berkurang. Penelitian ini menggunakan metode penelitian studi pustaka di mana penulis mencari data dan informasi dari berbagai jenis referensi seperti dokumen, baik dokumen yang berbentuk tertulis, dokumen yang berbentuk foto-foto, dokumen yang berbentuk gambar, maupun dokumen yang berbentuk elektronik yang dapat digunakan sebagai sumber dalam proses penelitian. Dapat disimpulkan bahwa hate speech merupakan kata, perbuatan, tulisan maupun aksi yang dapat menimbulkan terjadinya tindakan kekerasan yang merendahkan harkat dan martabat antar sesama manusia sehingga mengakibatkan Stigma dari pihak yang melakukan atau disebut pelaku maupun pihak yang menjadi korban dari tindakan tersebut. hate comment yang sering kali dilakukan di media sosial termasuk ke dalam ujaran kebencian. Indonesia memiliki beberapa peraturan yang mengatur tentang hate comment di antaranya UU ITE, KUHP, dan Surat Edaran Kapolri Nomor: SE/06/X/2015 tentang Penanganan Ujaran Kebencian (Hate Speech), Selain itu hate comment juga memiliki beberapa dampak buruk baik untuk korban maupun pelaku.
Tinjauan Yuridis atas Kebijakan Outsourcing di Indonesia dan Implikasinya terhadap Kesejahteraan Pekerja
Authors: Al Fath  , Nada Syifa Nurulhuda  , Virna Amalia Nur Permata
Published: January 2025

Penyaluran tenaga kerja oleh perusahaan pihak ketiga merupakan hal yang sudah lumrah praktiknya di Indonesia.  Namun paradigma terkait tentang penyaluran tenaga kerja ini masih menjadi suatu kekaburan hukum bagi sebagian publik yang berakibat pada kesejahteraan buruh pekerja.  Hal tersebut yang mendorong penulis untuk menyusun penelitian yang berinti pada kajian yuridis kebijakan Outsourcing dan implikasinya pada kesejahteraan buruh pekerja.  Berdasarkan hasil penelitian penulis dapat ditemukan bahwa regulasi umum yang mengatur terkait persoalan penyaluran tenaga kerja atau outsourcing adalah UU No. 13 Tahun 2003 tentang Ketenagakerjaan, UU No. 11 Tahun 2020 tentang Cipta Kerja dan Peraturan Menteri Ketenagakerjaan No. 19 Tahun 2012 serta persoalan yang kerap dihadapi adalah pengawasan hukum yang kurang ketat.  Terlepas dari hal tersebut, buruh outsourcing sering mendapat ketidakadilan bila terkait soal upah, tunjangan dan ketidakstabilan pekerjaan.
ANALISIS SISTEM PEMERINTAHAN DAN PERLINDUNGAN HUKUM TERHADAP HAK ULAYAT MASYARAKAT ADAT BADUY
Authors: Tuasalamony Adzra Ardelia
Published: January 2025

Sistem pemerintahan yang dianut oleh suku Baduy menunjukkan perbedaan signifikan dengan tatanan pemerintahan yang umumnya berlaku di tingkat desa, seperti yang diatur dalam kerangka hukum nasional yang tercantum dalam Undang-Undang Nomor 23 Tahun 2014 terkait dengan Pemerintahan Daerah dan Undang-Undang Nomor 6 Tahun 2014 tentang Desa. Penelitian ini bertujuan untuk mengidentifikasi sistem pemerintahan tradisional masyarakat Baduy dan juga melihat bagaimana perlindungan hukum terhadap hak ulayat mereka diatur. Metode penelitian yang dipergunakan yaitu pendekatan hukum normatif dengan studi kasus normatif, yang mengacu pada penafsiran dan aplikasi hukum yang dilakukan secara teoritis. Dalam sistem pemerintahan Baduy, terdapat pemerintahan lokal yang disebut pikukuh karuhun yang dipimpin oleh tiga pemimpin adat, dikenal sebagai Puun, yang memiliki kedudukan di tiga wilayah berbeda, yaitu Cibeo, Cikartawana, dan Cikeusik. Masyarakat Baduy dan Kasepuhan mayoritas menggantungkan mata pencaharian mereka pada pertanian dengan kepemilikan lahan komunal, yang dikenal sebagai hak ulayat, yang aturannya mengacu pada norma adat. Sebagai respons terhadap perlindungan hak ulayat tersebut, Pemerintah wilayah Lebak sudah melakukan pengesahan Peraturan Daerah Kabupaten Lebak Nomor 32 Tahun 2001.
CHARACTERISING THE KEY ELEMENTS AFFECTING RBT TEACHERS’ COMPETENCE IN TVET EDUCATION IN PENANG
Authors: Zakaria Suraya , Md Osman Siti Zuraidah
Published: January 2025

In the subject of Design and Technology (RBT), the application of Information and Communication Technology (ICT) elements through technology applications can strengthen basic skills in a more effective learning process. Some issues arise as a result of the increase in technology, but there are gaps in the provision and support for teachers to adapt technology in their teaching. This study aims to identify the factors that cause RBT teachers to lack the skills to integrate technology into teaching practice and analyze the weaknesses of using technology in the classroom. Using qualitative research methods, five RBT teachers in Penang were interviewed. The results of the study found lack of knowledge, training and support, technology skills, as well as problems with devices and technology infrastructure to be the main obstacles. Despite the challenges, the findings of the study also show that the use of technology has great potential to increase the interest and effectiveness of teaching. This study suggests stakeholders to provide adequate equipment and more comprehensive training for RBT teachers. This study also contributes to the technology education literature by providing empirical evidence on the challenges faced as well as strategies to improve the use of technology in teaching.
GAMIFICATION ADAPTATION IN TEACHING AND LEARNING AMONG THE SECONDARY SCHOOL TEACHERS IN MALAYSIA
Authors: Ismail Zati Hanani , Shahabuddin Mohd Zaki , Muhamad Fatimah Noni
Published: January 2025

The integration of gamification in education garnered significant attention in recent years to engage learners and enhance their learning experiences innovatively. Gamification in educational setting is an approach that uses games to support students learn. However, there are a few challenges faced by the secondary school teachers on how to adapt gamification in teaching and learning process. Therefore, this study aims to obtain information, then descriptively analyse the awareness and knowledge of gamification and the challenges of adapting gamification in teaching and learning with respect to the adaptation of gamification in teaching and learning. Based on this study, most teachers were highly aware and have knowledge about gamification in teaching and learning. The potential advantages and disadvantages of adapting gamification in teaching and learning also can be identified from this study. A questionnaire is used as the instrument of the research. The respondents were the secondary school teachers from all around Malaysia. There is a total of 50 questionnaires that has been collected and were returned satisfactorily. Statistical Package for Social Science (SPSS) computer software program is used to analyse and interpret the data. A descriptive analysis that includes mean, standard deviation and percentages for each component in the challenges of adapting gamification in teaching and learning. Most of the respondents have an uncertain view of adapting the gamification in teaching and learning process but agreed about the potential of gamification in sustaining the learner engagement and motivation.
Correlation of Bullying Behaviour Experienced with the Mental Health of High School Students in Tomohon City
Authors: Siregar Dina Mariana
Published: January 2025

This study aimed to determine the impact of bullying behavior on the mental health of high school students in Tomohon City. The results of this study show that bullying has an impact on the mental health of high school students in Tomohon City, as shown by the results of research conducted from May 1, 2023 to May 30, 2023 over 40 high school students in Tomohon City. Data collection was performed by assigning harassment impact scale via a Google Form to subjects who met the criteria. The results of multiple regression analysis obtained F = 17,189 (p < 0,001), and the results of the Pearson correlation test show that the significance value (p < 0,001), so it can be concluded that variables X and Y are correlated with each other. The Pearson correlation value of variables X and Y is -0,558. These results indicate that there is a negative relationship between bullying and mental health of high school students in Tomohon City. Based on these results, the hypothesis that the effects of bullying are negatively correlated with the mental health of high school students in Tomohon City is accepted. After performing the simple regression analysis test, an R-squared of 0.311 (p < 0,001). This means that after partial testing, bullying affected 31,1% of students' mental health and 68,9% were influenced by other factors not considered in the study.
The effectiveness of video modeling to reduce submissive behavior in intellectually disabled students who are victims of bullying in inclusive school
Authors: Alkaff Ainun , Alkaff Noor
Published: January 2025

This study aimed to explore the effectiveness of video modeling in reducing submissive behavior in students with intellectual disabilities who have been victims of bullying in inclusive school. Submissive behavior, characterized by the inability to defend oneself or express opinions, often emerges when faced with stressful situations. Video modeling was used as an intervention to provide examples of assertive behavior that the students could imitate. This research employed a single-subject method involving a student with an intellectual disability identified as a victim of bullying. The student participated in six video modeling sessions depicting positive social interaction scenarios. Data was collected through direct observation, interviews, psychological tests, and informal assessments administered to teachers and parents. The analysis results showed a significant improvement in the student’s ability to express opinions and a reduction in submissive behavior. These findings indicate that video modeling can be an effective tool in supporting students with intellectual disabilities to overcome bullying and reduce submissive behavior in inclusive school environments.
Giving aromatherapy to reduce mental workload of human resources department employees of company X
Authors: Irmawati Ayu
Published: January 2025

This study aims to reduce mental workload through the provision of aromatherapy to PT. X employees. Mental workload is a problem that is often experienced by employees of PT X which in the long run will affect both physical health such as the appearance of headaches, fever, and heart attacks and mental such as the emergence of anxiety, sadness, and despair. Aromatherapy is a therapeutic action that utilizes essential oils with the aim of improving a person's physical and psychological health. This study applied a quantitative approach with pre-test and post-test design. The subjects in this study were 6 people. The administration of aromatherapy was carried out for 3 days, and its effectiveness was measured using the NASA-TLX method. Based on results, there is a significant decrease of mental workload. The findings of this study have practical indications specifically for HR department employees and agencies in helping employees to reduce mental workload. By integrating the use of aromatherapy in helping to reduce the mental workload of employees in the work area, it is expected that employees can feel more relaxed and calmer when completing work.
Implementation of self-instruction techniques to reduce exam anxiety in junior high school students
Authors: Istighfari Mirzarisma
Published: January 2025

This research aimed to reduce exam anxiety using the self-instruction technique in students of SMP Muhammadiyah 1 Gresik. Anxiety often occurs before and during exams, and it can manifest in various physical, emotional, and cognitive symptoms. This study employed an experimental quantitative approach with one group pre-test and post-test design. The self-instruction technique was applied over a set period, and the effectiveness was measured using anxiety scales before and after the intervention. The results showed a significant reduction in students' anxiety levels, highlighting the positive impact of self-instruction techniques in managing exam-related anxiety.
The relationship between organizational climate and employee work loyalty in the X Department of West Sumatra Province
Authors: Kandarvi Rini , Dewinda Herio Rizki , Fitriany Rany , Farid Risanita Fardian
Published: January 2025

This research aims to determine the relationship between organizational climate and employee work loyalty at department X, West Sumatra Province. The measuring instruments used in this research are the organizational climate and work loyalty scales. The sampling used a saturated sampling technique with a sample size of 145 employees of department X of West Sumatra Province. The index discrimination item and reliability tests of both instruments showed that they were good (organizational climate scale 0,329 < rix < 0,842; α = 0,927, while the work loyalty scale 0,338 < rix < 0,760; α = 0,932). The hypothesis test in this research uses the Pearson Product Moment correlation with result analysis value of 0,752 (p < 0,001) meaning there is a significant correlation between organizational climate and employee work loyalty at department X, West Sumatra Province, where the direction of the correlation between the two variables is positive, show that if employee has a high organizational climate, then the employee will have high work loyalty, and conversely, if an employee has a low organizational environment, then the employee will have low work loyalty.
Thermal Image Classification of Autistic Children Using Res-Net Architecture
Authors: Ahmadiar Ahmadiar , Melinda Melinda , Muthiah Zharifah , Zainal Zulfan , Mina Rizky Muharratul
Published: January 2025

The thermal Image Classification Method has been widely used for significant applications in many fields, including thermal images of the face. This study presents a method for thermal facial classification in children with autism spectrum disorder (ASD). Children with ASD have a neurological disorder that affects communication skills essential in daily life and often causes difficulties in social situations. As we know, the diagnosis of ASD currently still relies on human methods and does not yet have definite biological markers. Early diagnosis of ASD has a significant positive impact, especially in children. Deep learning techniques, especially in facial medical image analysis, have become a new research focus in ASD detection. Initial screening using a Convolutional Neural Network (CNN) model with a transfer learning approach offers great potential for early diagnosis of ASD. The use of thermal imaging as a passive method to analyze ASD-related physiological signals has been proposed. In previous research, a deep learning model was developed to classify the faces of autistic children using thermal images. Therefore, this study aims to create a new Thermal Image Classification model for Autistic Children Using Res-Net Architecture. The architectures applied are ResNet-18, ResNet-34, and ResNet-50. As a comparison system, several of the same parameter values are used: epoch 100, batch size 2, SGD, Cross-entropy, learning rate 0.001, and momentum 0.9. The study test results show that the results of ResNet-18 are 97.22%, ResNet-34 99.22%, and ResNet-50 99.41%. Based on these results, ResNet-50 has the highest value.
Development of Symptomatic Adjacent and Remote Level Compression Fractures Following Balloon-assisted Kyphoplasty in a Series of 1,318 Patients
Authors: Gerszten Peter C.
Published: January 2025

BACKGROUND: Balloon-assisted kyphoplasty (BAK) is a minimally invasive procedure to treat vertebral compression fractures (VCF). BAK not only restores vertebral height and corrects kyphotic deformity by cement augmentation, but it also may alter spinal biomechanics, leading to subsequent adjacent level VCFs.

OBJECTIVES: This study aims to investigate the timing, location, and incidence of new VCFs following BAK and identify the risk factors associated with their occurrence.

STUDY DESIGN: Single-institution observational study.

METHODS: A prospectively collected cohort of 1,318 patients who underwent BAK by a single-surgeon from 2001 through 2022 was analyzed. The patients had pain that was unresponsive to nonsurgical management and a VCF secondary to osteoporosis, trauma, or neoplasm. The time between the index and subsequent fracture, fracture level, number of initial fractures, age, body mass index (BMI), tobacco use, and chronic corticosteroid use were recorded.

RESULTS: Of 1,318 patients, 204 (15.5%) patients underwent a second BAK procedure an average of 373 days following BAK (range: 2–3,235 days). Third, fourth, and fifth procedures were less common (45, 12, and 6 patients, respectively). A total of 142 patients (69.6%) developed a subsequent fracture adjacent to the index level; adjacent and remote level fractures developed at different times (mean: 282 vs 581 days, P = 0.001). Patients treated for multiple VCFs in a single surgery were more likely to develop subsequent VCFs (P = 0.024) and at adjacent levels (P = 0.007). Subsequent VCFs were associated with older age (P < 0.001), women (P = 0.045), osteoporosis (P < 0.001), and chronic corticosteroid use (P < 0.001). A subgroup analysis of 812 (61.6%) patients who underwent BAK for degenerative indications revealed that osteoporosis (b = 0.09; 95% CI, 0.03–0.16; P = 0.005) and chronic corticosteroid use (b = 0.06; 95% CI, 0–0.11; P = 0.055) were associated with adjacent level fracture. For the entire cohort, almost every patient treated for both a thoracic and lumbar fracture (92.3%) developed an adjacent level second fracture (P = 0.005).

LIMITATIONS: The true incidence of post-BAK fractures may be underestimated as surveillance is not routine in asymptomatic or osteoporotic patients.

CONCLUSIONS: Symptomatic post-BAK VCFs are infrequent and may occur long after the initial procedure. Nearly two-thirds of subsequent fractures in our study occurred adjacent to the initially treated level; almost every patient who suffered thoracic and lumbar fractures at the same time developed an adjacent level second fracture. Additionally, osteoporosis and chronic corticosteroid use were associated with adjacent level fractures in patients who underwent surgery for degenerative indications.

KEY WORDS: Kyphoplasty, balloon-assisted kyphoplasty, cement augmentation, osteoporosis, spine fracture, compression fracture, adjacent level fracture
Technique of Awake Computed Tomography–guided Percutaneous Balloon Compression of the Gasserian Ganglion for Trigeminal Neuralgia
Authors: Lin Huidan
Published: January 2025

BACKGROUND: The classic percutaneous balloon compression (PBC) technique is used to complete an operation under the guidance of C-arm radiography under general anesthesia, making communication with patients during the operation impossible. It is not accurate or objective to predict the classic technique’s curative effect solely by determining whether the projection of the x-ray lateral image of the filled balloon is pear-shaped.

OBJECTIVES: This study aimed to upgrade classic PBC to awake computed tomography (CT)-guided PBC technology under conscious local anesthesia and analgesia monitoring.

STUDY DESIGN: Prospective clinical study.

SETTING: Department of Anesthesiology and Pain Medical Center, Jiaxing, People’s Republic of China.

METHODS: Puncture was designed and guided by CT scanning, and the curative effect was assessed by asking the patients about what they are feeling during the operation.

RESULTS: CT can design the puncture path and accurately guide puncture, observe the position and shape of the balloon through 3-dimensional reconstruction during the operation, and judge the curative effect according to the patient’s chief concern.

LIMITATIONS: Local anesthetic analgesia is not perfect, resulting in some patients experiencing pain during surgery.

CONCLUSIONS: PBC can be completed under conscious local anesthesia and analgesia. Its curative effect and operative end standard can be determined according to the patient’s chief concern. Under CT guidance, the puncture path can be designed to complete an accurate puncture and to intuitively understand the position and shape of the balloon.

KEY WORDS: Trigeminal neuralgia, computed tomography guidance, conscious sedation, percutaneous balloon compression
Tinjauan Kriminologi Terhadap Kekerasan Dalam Rumah Tangga dan Upaya Pencegahannya
Authors: Karnadi Wenny Tazira
Published: January 2025

Kekerasan dalam rumah tangga (KDRT) dikenal sebagai kekerasan domestik (domestic violence), merupakan suatu masalah yang dapat terjadi di semua lapisan masyarakat. Tujuan penelitian ini adalah sebagai berikut: 1. Menentukan faktor-faktor yang menyebabkan kekerasan dalam rumah tangga dan 2. Menentukan upaya yang bisa dilakukan untuk mencegah kekerasan dalam rumah tangga. Metode penelitian yang digunakan berupa pendekatan hukum empiris dan studi kepustakaan. Pada penelitian ini, pola pikir induktif digunakan untuk menganalisis data dari sudut pandang kriminologi. Hasil penelitian dan diskusi menunjukkan bahwa 1. (a) Faktor sosio demografis yaitu umur, pendidikan, dan pekerjaan; (b) Faktor ekonomi/pendapatan rendah; (c) Faktor hubungan dalam rumah tangga; (d) Faktor perselingkuhan dan (e) Faktor hubungan suami-istri. (2) Upaya penanggulangan yaitu, upaya preemtif, preventif, dan represif.
Kajian Yuridis mengenai Hak Waris Perempuan dalam Hukum Islam Kontemporer
Authors: Rizky Esty Shofiyati Khasanatur , La dauwi La
Published: January 2025

Abstrak
Artikel ini mengkaji mengenai hak perempuan terhadap waris dalam lingkup Hukum Islam kontemporer (modern) melalui pendekatan yuridis. Hukum Islam telah mengatur dalam Al-Qur'an dan Hadis terkait hak waris perempuan, namun pada kenyataannya dalam Masyarakat modern ini sering kali terjadi permasalahan dalam mengimplementasikannya. Kajian ini berfokus pada analisis secara hukum terhadap hak waris perempuan dalam Hukum Islam, perbandingan dengan hukum waris adat setempat, dan perkembangannya dalam interpretasi masa modern. Kajian ini juga mengeksplorasi berbagai pandangan ahli agama terkait kesetaraan gender dalam pembagian waris. Hasil membuktikan bahwa meskipun hak perempuan telah diatur dalam Al-Qur'an dan Hadis yang diketahui sebagai aturan dasar Islam, sering kali terjadi diskriminatif yang dilakukan oleh masyakarat dikarenakan perbedaan dan pengaruh budaya dan adat lingkungan. Oleh karena itu, perlu adanya kesadaran masyarakat untuk bersikap adil dan menyetarakan hak perempuan yang telah ada sesuai aturan dalam Islam tanpa adanya diskriminasi. Kajian ini juga membahas terkait edukasi masyakarat dan reformasi hukum dengan tujuan memastikan hak waris perempuan dipenuhi sesuai dengan syariat agama Islam yang berlaku dan memenuhi unsur keadilan pada masa modern.
 
Kata kunci: Kajian yuridis; Hukum Islam; hak waris perempuan; Warisan.
Thalassemia and Reproductive Health: An Analysis of Gonadal Function in Beta Thalassemia Major Patients in a Tertiary Care Population
Authors: Islam Dr. Tahmidul , Wasim Dr. Mohammed , Akhter Dr. Nasrin , Sharmin Dr. Mahbuba , Islam Dr. Kazi Mohammad Kamrul , Rahman Dr. Sifat Naisum , Alam Dr. Sabrina
Published: January 2025

Introduction: Thalassemia, a hereditary hemoglobinopathy, causes chronic hemolytic anemia and complications like hypogonadism due to iron overload and endocrine dysfunction. Despite advancements in transfusion and iron chelation therapies, gonadal dysfunction remains prevalent. This study aims to assess gonadal function in beta-thalassemia patients, exploring hormonal profiles, pubertal development, and menstrual irregularities to improve disease management and quality of life in affected individuals. Objectives: To assess gonadal function and its association with serum ferritin levels and transfusion frequency in beta-thalassemia patients. Method and Materials: This cross-sectional study included 150 beta-thalassemia patients attending the Haematology Outpatient Department at BSMMU from January to December 2022. Data were collected through clinical history, physical examinations, and laboratory tests, including hemoglobin, serum ferritin, hormonal profiles (LH, FSH, testosterone, estradiol), and Tanner staging. Statistical analysis was performed using SPSS Version 21.0. Ethical approval and informed consent were obtained before initiating the study. Results: Among 150 patients, the majority (35.3%) were aged 10–15 years, with 61.3% males and 34.7% students. Severe anemia (Hb ≤7 g/dL) was seen in 33.3%, and 28.7% required 6–10 blood transfusions annually. Ferritin levels of 2001–3000 ng/mL were most common (40%). Secondary hypogonadism was observed in 46%, and 27.3% were in Stage III Tanner puberty development. Conclusion: This study highlights severe anemia, frequent transfusion dependence, elevated ferritin levels, and significant gonadal dysfunction in beta-thalassemia patients.