bluuebunny/crossref_metadata_2025 huggingface dataset:
Influence of Cooling Methods on the Residual Mechanical Behavior of Fire-Exposed Concrete: An Experimental Study
Authors: Carvalho Espedito Felipe Teixeira de , Silva Neto João Trajano da , Soares Junior Paulo Roberto Ribeiro , Maciel Priscila de Souza , Fransozo Helder Luis , Bezerra Augusto Cesar da Silva , Gouveia Antônio Maria Claret de
Published: October 2019

This work reports the main conclusions of a study on the mechanical behavior of concrete under ISO 834 fire with different cooling methods. The aim of this research was to provide reliable data for the analysis of structures damaged by fire. The experimental program used cylindrical concrete test specimens subjected to ISO 834 heating in a furnace up to maximum gas temperatures of 400, 500, 600, 700, and 800 °C. The compressive strength was measured in three situations: (a) at the different temperature levels reached in the furnace; (b) after a natural cooling process; and (c) after aspersion with water at ambient temperature. The results indicate that the concrete residual compressive strength is fairly dependent on the maximum temperature reached in the furnace and revealed that concrete of a lower strength preserved relatively higher levels of strength. The cooling method significantly influenced the strength, albeit at a lower intensity. In all cases, the residual strength remained in the range of 38% to 67% of the strength at ambient temperature. The statistical analysis showed that the data obtained by the experimental program are significant and confirmed the influence of the conditions imposed on the residual strength.
Effect of Surface Active Agent (SAA) on 50/70 Bitumen Foaming Characteristics
Authors: Iwański Mateusz M. , Chomicz-Kowalska Anna , Maciejewski Krzysztof
Published: October 2019

To ensure the standard properties of half-warm asphalt (HWA) mixes produced with foamed bitumen, the binder needs to have the best possible characteristics. One way to attain this is to modify the bitumen before it is foamed. The 50/70 penetration bitumen used in this study, was modified with a surface active agent (SAA) at different rates (0.2%, 0.4%, and 0.6% by wt.). The effect of the modifier on the bitumen properties (penetration, softening point, the Fraass breaking point, dynamic viscosity at 60 °C, 90 °C, and 135 °C) and on the binder foaming parameters (expansion ratio - ER, half-life - HL, foam index - FI) was investigated and the optimum quantity of foaming water was determined. Statistical analysis of the results showed that the addition of 0.6% SAA had the most beneficial effect on the set of 50/70 bitumen standard properties and foaming characteristics.
Impact of Ag2O Content on the Optical and Spectroscopic Properties of Fluoro-Phosphate Glasses
Authors: Ennouri Marwa , Kuusela Luukas , Jlassi Ifa , Gelloz Bernard , Petit Laeticia , Elhouichet Habib
Published: October 2019

Glasses with the system (84.60-x) NaPO3-5 ZnO-(9.40-x) NaF-x Ag2O-1 Er2O3, (x = 0, 2, 4, and 6) (mol%) were synthesized by the conventional melt-quenching method. The impact of the addition of Ag2O on the physical, thermal, structural, and optical properties of the glasses is discussed. The Judd-Oflet analysis was used to evaluate the radiative properties of the emission transitions of the glasses. The enhancement of luminescence properties due to Ag2O is discussed in terms of consequent changes in the local electromagnetic field, symmetry, and the ligand field around the Er3+ ion. The heat treatment of the glass was performed in order to precipitate Ag nanoparticles (NPs), which form as a layer at the surface of the heat-treated glasses as confirmed using scanning electron microscopy (SEM). The Ag NPs were found to increase the intensity of the emission at 1.5 µm.
Mechanical and Surface Properties of Resilient Denture Liners Modified with Chitosan Salts
Authors: Herla Maike , Boening Klaus , Meissner Heike , Walczak Katarzyna
Published: October 2019

Chitosan (CS) and its derivatives show antibacterial and antifungal properties and could help treat and prevent denture stomatitis (DS). Mechanical and surface properties of resilient denture liners were evaluated when modified with CS salts. CS-hydrochloride (CS-HCl) and CS-glutamate (CS-G) were added to resilient denture liners Ufi Gel P and Coe-Soft at four different concentrations (0.1%, 0.2%, 0.4%, 1% w/w) from which specimens were produced, as well as a control group of each material with no added CS salt. Ten specimens per group (Ø 35 mm, height 6 mm) were manufactured. They were stored in distilled water at 37 °C for a total of 30 days (d). Shore A hardness (SHA) and surface roughness (Ra) were evaluated after 24 h (T1), 7 d (T2), 14 d (T3) and 30 d (T4). Kruskal–Wallis and U-test (Bonferroni-Holm adjusted) were used for statistical analysis (p ≤ 0.05). Ra increased significantly once CS salts were added. SHA increased significantly for some groups, but all specimens fulfilled requirements set by ISO 10139-2:2016. Modification with CS salts does not influence the mechanical properties of the modified resilient denture liners in a clinically relevant manner. Despite the increased roughness, the concept is suitable for further studies. Especially antimicrobial/antibiofilm studies are needed.
Thermoelectric Properties of n-Type Molybdenum Disulfide (MoS2) Thin Film by Using a Simple Measurement Method
Authors: Ashraf Shakeel , Forsberg Viviane , Mattsson Claes G. , Thungström Göran
Published: October 2019

In this paper, a micrometre thin film of molybdenum disulfide (MoS2) is characterized for thermoelectric properties. The sample was prepared through mechanical exfoliation of a molybdenite crystal. The Seebeck coefficient measurement was performed by generating a temperature gradient across the sample and recording the induced electrical voltage, and for this purpose a simple measurement setup was developed. In the measurement, platinum was utilized as reference material in the electrodes. The Seebeck value of MoS2 was estimated to be approximately −600 µV/K at a temperature difference of 40 °C. The negative sign indicates that the polarity of the material is n-type. For measurement of the thermal conductivity, the sample was sandwiched between the heat source and the heat sink, and a steady-state power of 1.42 W was provided while monitoring the temperature difference across the sample. Based on Fourier’s law of conduction, the thermal conductivity of the sample was estimated to be approximately 0.26 Wm−1 K−. The electrical resistivity was estimated to be 29 Ω cm. The figure of merit of MoS2 was estimated to be 1.99 × 10−4.
Strain-Hardening and High-Ductile Behavior of Alkali-Activated Slag-Based Composites with Added Zirconia Silica Fume
Authors: Choi Jeong-Il , Park Se-Eon , Nguyễn Huy Hoàng , Cha Sang Lyul , Lee Bang Yeon
Published: October 2019

This paper presents an experimental study on the effects of zirconia silica fume on the composite properties and cracking patterns of fiber-reinforced alkali-activated slag-based composites. Four mixtures were prepared with added zirconia silica fume and varying water-to-binder ratio. Polyethylene fiber was used as a reinforcing fiber for all the mixtures at a volumetric ratio of 2.0% cubic specimens and uniaxial tensile specimens were prepared to evaluate their density, compressive strength, and tensile behavior. The test results demonstrated that the compressive strength, tensile strength, and tensile strain capacity of the composite can be simultaneously improved by incorporating zirconia silica fume. A mixture incorporating zirconia silica fume showed high-ductile behavior of 26.5% higher tensile strength, and 13.7% higher tensile strain capacity than the mixture without zirconia silica fume. The composite with added zirconia silica fume also showed excellent cracking patterns, i.e., narrow crack spacing and crack width.
Fatigue Growth Behaviour of Two Interacting Cracks with Different Crack Offset
Authors: Jin Huijin , Cui Bing , Mao Ling
Published: October 2019

Under cyclic fatigue load, multiple cracks would significantly deteriorate the service life of the components with respect to the case of a single crack owing to the crack interaction. The present study aims to explore the effect of crack interaction on the fatigue growth behaviour of samples with different crack offset. In this study, fatigue crack growth tests were performed for samples containing a single crack and non-collinear cracks of different crack offset in an aluminum–lithium alloy. It was shown that the two facing non-collinear cracks changed their growth direction when the cracks were overlapped, resulting in load mode transfers from mode I to I + II mixed mode. Then, the interaction behaviour was studied by establishing the finite element models to calculate the stress intensity factor K of samples with different crack offset. The results indicated that the K decreased, largely owing to the shielding effect as the two cracks overlapped, leading to retardation of crack growth in the position of overlap, especially for the specimens with a small crack offset. It was also shown that the interaction effect could change from positive to negative during the process of the multiple cracks’ growth, thus leading to the acceleration or deceleration of crack growth rates, suggesting that the influence of interaction on cracks’ growth behaviour could vary with the different stages of crack growth.
Privacy-Preserved Approximate Classification Based on Homomorphic Encryption
Authors: Xiao Xiaodong , Wu Ting , Chen Yuanfang , Fan Xingyue
Published: October 2019

Privacy is a crucial issue for outsourcing computation, which means that clients utilize cloud infrastructure to perform online prediction without disclosing sensitive information. Homomorphic encryption (HE) is one of the promising cryptographic tools resolving privacy issue in this scenario. However, a bottleneck in application of HE is relatively high computational overhead. In this paper, we study the privacy-preserving classification problem. To this end, we propose a novel privacy-preserved approximate classification algorithm. It exploits a set of decision trees to reduce computational complexity during homomorphic evaluation computation formula, the time complexity of evaluating a polynomial is degraded from O n to O log n . As a result, for an MNIST dataset, the Micro- f 1 score of the proposed algorithm is 0.882 , compared with 0.912 of the standard method. For the Credit dataset, the algorithm achieves 0.601 compared with 0.613 of the method. These results show that our algorithm is feasible and practical in real world problems.
A New Approach to Non-Singular Plane Cracks Theory in Gradient Elasticity
Authors: Lurie Sergey A. , Volkov-Bogorodsky Dmitriy B. , Vasiliev Valery V.
Published: October 2019

A non-local solution is obtained here in the theory of cracks, which depends on the scale parameter in the non-local theory of elasticity. The gradient solution is constructed as a regular solution of the inhomogeneous Helmholtz equation, where the function on the right side of the Helmholtz equation is a singular classical solution. An assertion is proved that allows us to propose a new solution for displacements and stresses at the crack tip through the vector harmonic potential, which determines by the Papkovich-Neuber representation. One of the goals of this work is a definition of a new representation of the solution of the plane problem of the theory of elasticity through the complex-valued harmonic potentials included in the Papkovich-Neuber relations represented in a symmetric form, which is convenient for applications. It is shown here that this new representation of the solution for the mechanics of cracks can be written through one harmonic complex-valued potential. The explicit potential value is found by comparing the new solution with the classical representation of the singular solution at the crack tip constructed using the complex potentials of Kolosov-Muskhelishvili. A generalized solution of the singular problem of fracture mechanics is reduced to a non-singular stress concentration problem, which allows one to implement a new concept of non-singular fracture mechanics, where the scale parameter along with ultimate stresses determines the fracture criterion and is determined by experiments.
Pleurotus highking Mushroom Induces Apoptosis by Altering the Balance of Proapoptotic and Antiapoptotic Genes in Breast Cancer Cells and Inhibits Tumor Sphere Formation
Authors: Haque Md. Anwarul , Islam Md. Anwar Ul
Published: October 2019

Background and objectives: Mushrooms that have medicinal properties are part of many traditional diets. The aim of the present study was to use the human breast cancer cell line MCF-7 to investigate the anticancer activity of Pleurotus highking mushroom purified extract fraction-III (PEF-III) and to elucidate the possible mechanism of that activity. Materials and Methods: The effects of PEF-III on cell proliferation and viability were evaluated by a colony formation assay and an MTT assay, respectively. Cell morphological changes, annexin-V phycoerythrin and propidium iodide (PI) staining, DNA fragmentation, and caspase 3/7 activity assays were performed to determine the induction of apoptosis by PEF-III. The genes responsible for regulation of apoptosis were analyzed by means of Western blot analysis. In vitro tumor sphere formation assay was performed using a 3D sphere culture system. Results: PEF-III significantly reduced the proliferation and viability of MCF-7 cells. Cell shrinkage and rounding, and annexin-V phycoerythrin and PI staining followed by flow cytometry indicated that the cell death was due to apoptosis. Additionally, a laddering DNA pattern and increased levels of caspase-3/7 enzyme also corroborated the notion of apoptosis-mediated cell death. This incidence was further confirmed by upregulation of proapoptotic genes (p53 and its target gene, Bax) and downregulation of the expression of an antiapoptotic gene (Bcl-2). PEF-III also reduced the size and number of the tumor spheres in 3D culture conditions. Conclusions: The anticancer activity of PEF-III is due to induction of apoptosis by a shift in the balance of proapoptotic and antiapoptotic genes. Therefore, the findings of the present study may open a path to exploring potential drug candidates from the P. highking mushroom for combating breast cancer.
Quasi-Stationary Strength of ECAP-Processed Cu-Zr at 0.5 Tm
Authors: Blum Wolfgang , Dvořák Jiři , Král Petr , Eisenlohr Philip , Sklenička Vaclav
Published: October 2019

The influence of the grain structure on the tensile deformation strength is studied for precipitation-strengthened Cu-0.2%Zr at 673K. Subgrains and grains are formed by equal channel angular pressing (ECAP) and annealing. The fraction of high-angle boundaries increases with prestrain. Subgrains and grains coarsen during deformation. This leads to softening in the quasi-stationary state. The initial quasi-stationary state of severely predeformed, ultrafine-grained material exhibits relatively high rate-sensitivity at relatively high stresses. This is interpreted as a result of the stress dependences of the quasi-stationary subgrain size and the volume fraction of subgrain-free grains.
Recovery of Rare Earth Oxide from Waste NiMH Batteries by Simple Wet Chemical Valorization Process
Authors: Ahn Nak-Kyoon , Swain Basudev , Shim Hyun-Woo , Kim Dae-Weon
Published: October 2019

Nickel metal hydride (NiMH) batteries contain a significant amount of rare earth metals (REMs) such as Ce, La, and Nd, which are critical to the supply chain. Recovery of these metals from waste NiMH batteries can be a potential secondary resource for REMs. In our current REM recovery process, REM oxide from waste NiMH batteries was recovered by a simple wet chemical valorization process. The process followed the chemical metallurgy process to recover REM oxides and included the following stages: (1) H2SO4 leaching; (2) selective separation of REM as sulfate salt from Ni/Co sulfate solution; (3) metathesis purification reaction process for the conversion REM sulfate to REM carbonate; and (4) recovery of REM oxide from REM carbonate by heat treatment. Through H2SO4 leaching optimization, almost all the metal from the electrode active material of waste NiMH batteries was leached out. From the filtered leach liquor managing pH (at pH 1.8) with 10 M NaOH, REM was precipitated as hydrated NaREE(SO4)2·H2O, which was then further valorized through the metathesis reaction process. From NaREE(SO4)2·H2O through carbocation, REM was purified as hydrated (REM)2CO3·H2O precipitate. From (REM)2CO3·H2O through calcination at 800 °C, (REM)2O3 could be recovered.
Effect of the δ Phase on the Tensile Properties of a Nickel-Based Superalloy
Authors: Zhu Qiang , Chen Gang , Wang Chuanjie , Cheng Lukuan , Qin Heyong , Zhang Peng
Published: October 2019

Nickel-based superalloys are widely used in aerospace and other fields due to their excellent properties. In this study, the aging treatment and tensile tests of a GH4169 alloy were carried out. The effects of the δ phase on the alloy’s mechanical properties and fracture behavior were studied. The results showed that the appearance of the δ phase changed from a short rod shape to a needle shape with an increase in aging time. The precipitation method changed from a single mode of precipitation along the grain boundary to two modes of precipitation along the grain boundary and direct precipitation inside the grain. The yield strength and ultimate tensile strength of the alloy first increased and then decreased with an increase in aging time and were related with the microstructure of the δ phase. The similar Widmanstatten structure was not conducive to the mechanical properties of the alloy. The distribution of the δ phase led to the generation of inhomogeneous strain and limited the surface roughening during plastic deformation. The voids initiated at the interface between the δ phase and the matrix γ phase or directly from the δ phase fracture site.
Effect of Intermetallic Compound Layer on Peel Strength and Crack Propagation Behavior in Cu/Al/Cu Clad Composites
Authors: Kim Yong Keun , Hong Sun Ig
Published: October 2019

The effects of interfacial modification in tri-layered Cu/Al/Cu composites by heat treatment on interface stability and crack propagation were investigated. In order to investigate the crack path during the peel test, the intermetallic compound layer with the propagating crack was examined using electron backscatter diffraction (EBSD) analyses. The increase of peel strength from 7.8 to 9.1 N/mm in the tri-layered Cu/Al/Cu composite in the presence of thin discontinuous intermetallic compounds with heat treatment at 200–300 °C was accompanied by the increase of electrical conductivity from 65.3% IACS (International Annealed Copper Standard) to 66.8% IACS. Continuous intermetallic layers consisting of Al2Cu, AlCu, and Al4Cu9 were found in Cu/Al/Cu heat-treated at temperatures above 350 °C and its thickness increased rapidly and reached up to 35.2 μm at 500 °C. The peel strength drastically decreased to 5.75 N/mm after heat treatment at 400 °C, and it gradually increased as the heat treatment temperature was increased to 450 °C (5.91 N/mm) and 500 °C (6.16 N/mm). The increased peel strengths after heat treatment at 450 and 500 °C were accompanied by pronounced serrations of the peel strength–displacement curves. The amplitude of serration increased substantially with increasing annealing temperature from 400 to 500 °C. The major crack along the interface propagated, mostly along the Al2Cu/AlCu boundary with some inclined cracks, propagated through the AlCu and Al4Cu9 intermetallic compound layers. The repetition of crack propagation along the interface and crack deflection through the intermetallic layer as an inclined crack induced the serrated surface on the peeled-off Cu plate, enhancing the interface toughening.
Static and Dynamic Thermal Properties of a Pd40Ni40Si20 Glassy Alloy
Authors: Drenchev Ludmil , Spassov Tony , Stefanov Georgi , Inoue Akihisa , Gyurov Stoyko
Published: October 2019

The thermal properties of a Pd40Ni40Si20 glassy alloy with the largest supercooled liquid region among the glassy alloys containing Si as a metalloid element are studied using static and dynamic measurement methods. The relatively wide supercooled liquid region of 45 K, defined by the temperature interval between the glass transition temperature (Tg) and the onset temperature of crystallization (Tx), and the viscosity of the supercooled liquid, varying from 2.7 × 1010 to 3.2 × 1011 Pa·s, make this glass suitable for the introduction of controlled pores by a viscous flow in the temperature range Tg~Tx. The obtained activation energy for crystallization, 272 ± 19 kJ/mol, is slightly higher than that of Tg (228 ± 11 kJ/mol), indicating the dominant contribution of the atomic transport barrier in the overall energy barrier for crystallization.
Solvent-Dependent Electrical Characteristics and Mechanical Stability of Flexible Organic Ferroelectric Field-Effect Transistors
Authors: Kim Do-Kyung , Lee Hyeonju , Zhang Xue , Bae Jin-Hyuk , Park Jaehoon
Published: October 2019

Flexible organic ferroelectric field-effect transistors (Fe-FETs) have attracted attention for next-generation memory applications. A fundamental understanding of the electrical properties and mechanical stability of transistors is a prerequisite to realizing practical flexible electronics. Here, we demonstrate the solvent-dependent electrical characteristics and mechanical stability of flexible Fe-FETs. Poly(vinylidene fluoride-trifluoro-ethylene) (P(VDF-TrFE)) based Fe-FETs were fabricated by using dimethylformamide (DMF) and methyl ethyl ketone (MEK) solvents on a polyimide substrate. P(VDF-TrFE) from DMF formed a smoother surface than a surface from MEK; the surface property greatly affected the electrical properties and mechanical stability of the devices. Larger hysteresis and higher mobility were obtained from Fe-FET using DMF compared to those characteristics from using MEK. Furthermore, Fe-FET using DMF showed lower degradation of on-current and mobility under repetitive mechanical stress than an MEK-based Fe-FET, due to its excellent semiconductor-insulator interface. These results will guide appropriate solvent selection and contribute to the improvement of flexible Fe-FET electrical properties and mechanical stability in the next generation of memory devices.
Nonlinear Coupled Vibration of Electrically Actuated Arch with Flexible Supports
Authors: Wang Ze , Ren Jianting
Published: October 2019

The nonlinear coupled vibration of an electrically actuated arch microbeam has attracted wide attention. In this paper, we studied the nonlinear dynamics of an electrically actuated arch microbeam with flexible supports. The two-to-one internal resonance between the first and second modes is considered. The multiple scales method is used to solve the governing equation. Four first-order ordinary differential equation describing the modulation of the amplitudes and phase angles were obtained. The equilibrium solution and its stability are determined. In the case of the primary resonance of the first mode, stable periodic motions and modulated motions are determined. The double-jumping phenomenon may occur. In the case of the primary resonance of the second mode, single-mode and two-mode solutions are possible. Moreover, double-jumping, hysteresis, and saturation phenomena were found. In addition, the approximate analytical results are supported by the numerical results.
Comparative Transcriptomic Analysis of the Interaction between Penicillium expansum and Apple Fruit (Malus pumila Mill.) during Early Stages of Infection
Authors: Wang Kaili , Zheng Xiangfeng , Zhang Xiaoyun , Zhao Lina , Yang Qiya , Boateng Nana Adwoa Serwah , Ahima Joseph , Liu Jia , Zhang Hongyin
Published: October 2019

Blue mold, caused by Penicillium expansum, is an important postharvest disease of apple, and can result in significant economic losses. The present study investigated the interaction between P. expansum and wounded apple fruit tissues during the early stages of the infection. Spores of P. expansum became activated one hour post-inoculation (hpi), exhibited swelling at 3 hpi, and the germ tubes were found entering into apple tissues at 6 hpi. RNA-seq was performed on samples of P. expansum and apple fruit tissue collected at 1, 3, and 6 hpi. The main differentially expressed genes (DEGs) that were identified in P. expansum were related to interaction, cell wall degradation enzymes, anti-oxidative stress, pH regulation, and effectors. Apple tissues responded to the presence of P. expansum by activating pathogen-associated molecular pattern (PAMP)-triggered immunity (PTI) at 1 hpi, then activated effector-triggered immunity (ETI) at 3 hpi. This research provides new information on the interaction between P. expansum and apple fruit tissue at an early stage of the infection process.
A Comparison of Constitutive and Inducible Non-Endogenous Keto-Carotenoids Biosynthesis in Synechocystis sp. PCC 6803
Authors: Menin Barbara , Lami Andrea , Musazzi Simona , Petrova Anastasia A. , Santabarbara Stefano , Casazza Anna Paola
Published: October 2019

The model cyanobacterium Synechocystis sp. PCC 6803 has gained significant attention as an alternative and sustainable source for biomass, biofuels and added-value compounds. The latter category includes keto-carotenoids, which are molecules largely employed in a wide spectrum of industrial applications in the food, feed, nutraceutical, cosmetic and pharmaceutical sectors. Keto-carotenoids are not naturally synthesized by Synechocystis, at least in any significant amounts, but their accumulation can be induced by metabolic engineering of the endogenous carotenoid biosynthetic pathway. In this study, the accumulation of the keto-carotenoids astaxanthin and canthaxanthin, resulting from the constitutive or temperature-inducible expression of the CrtW and CrtZ genes from Brevundimonas, is compared. The benefits and drawbacks of the two engineering approaches are discussed.
Geopolymer-TiO2 Nanocomposites for Photocsatalysis: Synthesis by One-Step Adding Treatment Versus Two-Step Acidification Calcination
Authors: Yang Xiaohui , Liu Yi , Yan Chunjie , Peng Ronghua , Wang Hongquan
Published: October 2019

Geopolymer-TiO2 nanocomposites were prepared by two different techniques, namely the two-step acidification calcination treatment and one-step adding method. The potential photocatalytic activities of geopolymer-TiO2 nanocomposites prepared by the two different methods were tested and compared. Nanocomposites prepared via the one-step process showed better photocatalytic activity. The amount of TiO2 particles loaded on the surface of the foaming materials was investigated by XRD and SEM-Mapping. By comparing with the sample obtained from two-step treatment, the TiO2 particles were distributed uniformly on the surface of the foaming materials for the sample obtained from the one-step method in this study. Results showed that the specific surface area of the geopolymer-TiO2 prepared by the one-step treatment process (28.67 m2/g) was significantly lower than the two-step acidification calcination process (215.04 m2/g), while the photocatalytic efficiency with methylene blue trihydrate (MB) was better. This is due to the more stable structure of geopolymer-TiO2 nanocomposites, the better dispersion and more loading of TiO2 particles on the foaming materials surfaces, leading to the enhanced photocatalytic activity.
Geochemistry and Mineralogy of Basalts from the South Mid-Atlantic Ridge (18.0°–20.6°S): Evidence of a Heterogeneous Mantle Source
Authors: Zhong Yun , Liu Weiliang , Sun Zhilei , Yakymchuk Chris , Ren Kefa , Liu Jinnan , Li Wei , Ma Yaoliang , Xia Bin
Published: October 2019

The South Mid-Atlantic Ridge is a typical slow-spreading ridge that represents a modern example to understand mantle composition and the evolution of mid-ocean ridge magmatism. In this paper, we investigate basalt samples dredged from four locations along the South Mid-Atlantic Ridge ranging from 18.0° to 20.6°S. The basalts belong to the tholeiitic series and exhibit normal mid-ocean ridge basalt (N-MORB) geochemical features with variable enrichments of Rb, Th, U, and Pb and depletions of Ba and Sr relative to primitive mantle. Some samples have negative Nb–Ta anomalies whereas others have positive Na–Ta anomalies to average N-MORBs. Plagioclase phenocrysts, microphenocrysts, and microlites occur in the in the matrix; phenocrysts and microphenocrysts are bytownite and labradorite in composition. Olivine phenocrysts are forsterite (Fo87 to Fo96). Chemical zoning in phenocrysts are interpreted to record crystal fractionation and magma mixing. Cores of plagioclase phenocrysts have higher anorthite values (An72–83) and estimated crystallization temperatures (~1180–1240 °C) that may suggest a xenocrystic origin. The lower anorthite proportions of rims of plagioclase phenocrysts (An65–71) and microphenocrysts (An54–72) yield lower estimated crystallization temperatures of ~1090–1120 °C and ~980–1060 °C, respectively. Rims of plagioclase phenocrysts and microphenocrysts may be generated in different environments such as magma chambers or magma channels, respectively. The basalt samples probably originated from partial melting of a depleted mantle spinel lherzolite source with a minor contribution of enriched materials possibly derived from the Saint Helena plume and subcontinental lithospheric mantle in the asthenosphere. Variable compositions of the basalt samples suggest heterogeneous mantle that includes depleted and enriched components at the South Mid-Atlantic Ridge between 18.0°–20.6°S.
Influence of pH on Molecular Hydrogen (H2) Generation and Reaction Rates during Serpentinization of Peridotite and Olivine
Authors: Huang Ruifang , Sun Weidong , Song Maoshuang , Ding Xing
Published: October 2019

Serpentinization produces molecular hydrogen (H2) that is capable of supporting communities of microorganisms in hydrothermal fields, which suggests that serpentinization may be closely related to the origin of life at the early history of the Earth and possibly other planets. In this study, serpentinization experiments were performed at 300 °C and 3.0 kbar with natural olivine and peridotite as starting reactants to quantify the influence of acidic and alkaline solutions on the processes of serpentinization. The results reveal that acidic and alkaline solutions greatly influence molecular hydrogen (H2) generation and the rates of serpentinization. Acidic (pH = 2.50) and alkaline solutions (pH = 13.5) increased H2 production and the rates of peridotite serpentinization. Highly acidic solutions (2 M HCl), however, decreased the production of H2 after peridotite serpentinization by around two orders of magnitude. The decrease in H2 production was associated with a sharp decline in the rates of reaction; e.g., when peridotite was reacted with neutral solutions (0.5 M NaCl), 88% of reaction progress was achieved after an experimental duration of 27 days, and the reaction extent decreased by ~50% for experiments with highly acidic solutions (2 M HCl) over the same period. In contrast, for experiments with solely olivine, highly acidic solutions (2 M HCl) promoted the rates of olivine serpentinization and H2 production. The contrasting effect of highly acidic solutions (2 M HCl) on the processes of olivine and peridotite serpentinization may reflect the influence of pyroxene minerals, which could release SiO2 during peridotite serpentinization and, consequently, hydrogen generation and reaction rates may decrease. The experimental results of this study suggest that H2 production and the rates of serpentinization can be greatly influenced by acidic and alkaline solutions and co-existing minerals (e.g., pyroxene).
Reusable Surface-Enhanced Raman Spectroscopy Substrates Made of Silicon Nanowire Array Coated with Silver Nanoparticles Fabricated by Metal-Assisted Chemical Etching and Photonic Reduction
Authors: Bai Shi , Du Yongjun , Wang Chunyan , Wu Jian , Sugioka Koji
Published: October 2019

Surface-enhanced Raman spectroscopy (SERS) has advanced over the last four decades and has become an attractive tool for highly sensitive analysis in fields such as medicine and environmental monitoring. Recently, there has been an urgent demand for reusable and long-lived SERS substrates as a means of reducing the costs associated with this technique To this end, we fabricated a SERS substrate comprising a silicon nanowire array coated with silver nanoparticles, using metal-assisted chemical etching followed by photonic reduction. The morphology and growth mechanism of the SERS substrate were carefully examined and the performance of the fabricated SERS substrate was tested using rhodamine 6G and dopamine hydrochloride. The data show that this new substrate provides an enhancement factor of nearly 1 × 108. This work demonstrates that a silicon nanowire array coated with silver nanoparticles is sensitive and sufficiently robust to allow repeated reuse. These results suggest that this newly developed technique could allow SERS to be used in many commercial applications.
Accurate Adapter Information Is Crucial for Reproducibility and Reusability in Small RNA Seq Studies
Authors: Zhong Xiangfu , Heinicke Fatima , Lie Benedicte A. , Rayner Simon
Published: October 2019

A necessary pre-processing data analysis step is the removal of adapter sequences from the raw reads. While most adapter trimming tools require adapter sequence as an essential input, adapter information is often incomplete or missing. This can impact quantification of features, reproducibility of the study and might even lead to erroneous conclusions. Here, we provide examples to highlight the importance of specifying the adapter sequence by demonstrating the effect of using similar but different adapter sequences and identify additional potential sources of errors in the adapter trimming step. Finally, we propose solutions by which users can ensure their small RNA-seq data is fully annotated with adapter information.
Polyphenol Effects on Cholesterol Metabolism via Bile Acid Biosynthesis, CYP7A1: A Review
Authors: Chambers Karen F. , Day Priscilla E. , Aboufarrag Hassan T. , Kroon Paul A.
Published: October 2019

Atherosclerosis, the main contributor to coronary heart disease, is characterised by an accumulation of lipids such as cholesterol in the arterial wall. Reverse cholesterol transport (RCT) reduces cholesterol via its conversion into bile acids (BAs). During RCT in non-hepatic peripheral tissues, cholesterol is transferred to high-density lipoprotein (HDL) particles and returned to the liver for conversion into BAs predominantly via the rate-limiting enzyme, cholesterol 7 α-hydroxylase (CYP7A1). Numerous reports have described that polyphenol induced increases in BA excretion and corresponding reductions in total and LDL cholesterol in animal and in-vitro studies, but the process whereby this occurs has not been extensively reviewed. There are three main mechanisms by which BA excretion can be augmented: (1) increased expression of CYP7A1; (2) reduced expression of intestinal BA transporters; and (3) changes in the gut microbiota. Here we summarise the BA metabolic pathways focusing on CYP7A1, how its gene is regulated via transcription factors, diurnal rhythms, and microRNAs. Importantly, we will address the following questions: (1) Can polyphenols enhance BA secretion by modulating the CYP7A1 biosynthetic pathway? (2) Can polyphenols alter the BA pool via changes in the gut microbiota? (3) Which polyphenols are the most promising candidates for future research? We conclude that while in rodents some polyphenols induce CYP7A1 expression predominantly by the LXRα pathway, in human cells, this may occur through FXR, NF-KB, and ERK signalling. Additionally, gut microbiota is important for the de-conjugation and excretion of BAs. Puerarin, resveratrol, and quercetin are promising candidates for further research in this area.
A Single Dose of The Mango Leaf Extract Zynamite® in Combination with Quercetin Enhances Peak Power Output During Repeated Sprint Exercise in Men and Women
Authors: Gelabert-Rebato Miriam , Martin-Rincon Marcos , Galvan-Alvarez Victor , Gallego-Selles Angel , Martinez-Canton Miriam , Vega-Morales Tanausú , Wiebe Julia C. , Fernandez-del Castillo Constanza , Castilla-Hernandez Elizabeth , Diaz-Tiberio Oriana , Calbet Jose A. L.
Published: October 2019

The mango leaf extract rich in mangiferin Zynamite® improves exercise performance when combined with luteolin or quercetin ingested at least 48 h prior to exercise. To determine whether a single dose of Zynamite® administered 1 h before exercise increases repeated-sprint performance, 20 men and 20 women who were physically active were randomly assigned to three treatments following a double-blind cross-over counterbalanced design. Treatment A, 140 mg of Zynamite®, 140 mg of quercetin, 147.7 mg of maltodextrin, and 420 mg of sunflower lecithin; Treatment B, 140 mg of Zynamite®, 140 mg of quercetin, and 2126 mg of maltodextrin and Treatment C, 2548 mg of maltodextrin (placebo). Subjects performed three Wingate tests interspaced by 4 min and a final 15 s sprint after ischemia. Treatments A and B improved peak power output during the first three Wingates by 2.8% and 3.8%, respectively (treatment x sprint interaction, p = 0.01). Vastus Lateralis oxygenation (NIRS) was reduced, indicating higher O2 extraction (treatment × sprint interaction, p = 0.01). Improved O2 extraction was observed in the sprints after ischemia (p = 0.008; placebo vs. mean of treatments A and B). Blood lactate concentration was 5.9% lower after the ingestion of Zynamite® with quercetin in men (treatment by sex interaction, p = 0.049). There was a higher Vastus Lateralis O2 extraction during 60 s ischemia with polyphenols (treatment effect, p = 0.03), due to the greater muscle VO2 in men (p = 0.001). In conclusion, a single dose of Zynamite® combined with quercetin one hour before exercise improves repeated-sprint performance and muscle O2 extraction and mitochondrial O2. consumption during ischemia. No advantage was obtained from the addition of phospholipids.
Novel Approaches for the Delivery of Anti-HIV Drugs—What Is New?
Authors: das Neves José
Published: October 2019

HIV/AIDS continues to be one of the most challenging individual and public health concerns of our days [...]
Supercritical Carbon Dioxide Antisolvent Fractionation for the Sustainable Concentration of Lavandula luisieri (Rozeira) Riv.- Mart Antimicrobial and Antioxidant Compounds and Comparison with Its Conventional Extracts
Authors: Giménez-Rota Carlota , Lorán Susana , Mainar Ana M. , Hernáiz María J. , Rota Carmen
Published: October 2019

Lavandula stoechas subsp. luisieri is a Spanish subspecies from the Lamiaceae family. Its essential oil has been traditionally used for several medical applications though little is known about other extracts. Similar to many other studies aiming to obtain traditional plant extracts to be used in different applications, this work evaluated the antioxidant and antimicrobial activities of Lavandula luisieri extracts and the correlation with their composition. Traditional hydrodistillation and ethanolic maceration were used to obtain the essential oil and the maceration extract, respectively. A green and sustainable methodology was applied to the maceration extract that was under a Supercritical Antisolvent Fractionation process to obtain a fine solid enriched in rosmarinic acid and the terpenes oleanolic and ursolic acids. Antimicrobial activities of all extracts and pure identified compounds (rosmarinic and ursolic acids) were evaluated against five bacterial strains; Listeria monocytogenes, Enterococcus faecium, Staphylococcus aureus, Salmonella Typhimurium and Escherichia coli and were compared with the pure compounds identified, rosmarinic and ursolic acids. All strains were sensitive against L. luisieri essential oil. The solid product obtained from the supercritical process was concentrated in the identified actives compared to the maceration extract, which resulted in higher antimicrobial and DPPH scavenging activities. The supercritical sustainable process provided L. luisieri compounds, with retention of their antimicrobial and antioxidant activities, in a powder exemptof organic solvents with potential application in the clinical, food or cosmetic fields.
Screening for Plant Volatile Emissions with Allelopathic Activity and the Identification of L-Fenchone and 1,8-Cineole from Star Anise (Illicium verum) Leaves
Authors: Kang Gaowa , Mishyna Maryia , Appiah Kwame Sarpong , Yamada Masaaki , Takano Akihito , Prokhorov Valery , Fujii Yoshiharu
Published: October 2019

One hundred and thirty-nine medicinal plant species were screened for their allelopathic activity through volatile emissions using Lactuca sativa as a test plant. Volatile emissions from the leaves of star anise (Illicium verum) showed the highest inhibition (100%) on the radicle and hypocotyl growth. Using headspace gas collection and gas chromatography-mass spectrometry (GC-MS), seven major volatile compounds from the leaves of star anise, including α-pinene, β-pinene, camphene, 1,8-cineole, D-limonene, camphor, and L-fenchone were detected. To determine volatile compounds that may contribute to the inhibitory activity of star anise, the allelopathic potential of individual volatiles from star anise was evaluated using the cotton swab bioassay. The EC50 was calculated for each of the seven identified compounds. L-fenchone showed the strongest growth inhibitory activity (EC50 is 1.0 ng/cm3 for radicle and hypocotyl growth of lettuce), followed by 1,8-cineole, and camphene. This is the first report that L-fenchone could be an important volatile allelochemical from the leaves of star anise. From the actual concentration of each volatile compound in headspace and EC50 value, we concluded that the four volatile compounds, including L-fenchone, 1,8-cineole, β-pinene, and camphene are the most important contributors to the volatile allelopathy of star anise.
Size-Controllable Melt-Electrospun Polycaprolactone (PCL) Fibers with a Sodium Chloride Additive
Authors: Piyasin Piyawat , Yensano Rattakarn , Pinitsoontorn Supree
Published: October 2019

Melt-electrospun polycaprolactone (PCL) fibers were fabricated by using NaCl as an additive. The size and morphology of the PCL fibers could be controlled by varying the concentration of the additive. The smallest size of the fibers (2.67 ± 0.57) µm was found in the sample with 8 wt% NaCl, which was an order of magnitude smaller than the PCL fibers without the additive. The melt-electrospun fibers were characterized using the differential scanning calorimeter (DSC), X-ray diffraction (XRD), and Fourier transform infrared spectroscopy (FTIR) techniques. Interestingly, a trace of NaCl was not found in any melt-electrospun fiber. The remaining PCL after melt-electrospinning was evaporated by annealing, and the NaCl residual was found in the glass syringe. The result confirmed that the NaCl additive was not ejected from the glass syringe in the melt-electrospinning process. Instead, the NaCl additive changed the viscosity and the polarization of the molten polymer. Two parameters are crucial in determining the size and morphology of the electrospun fibers. The higher NaCl concentration could lead to higher polarization of the polymer melt and thus a stronger electrostatic force, but it could also result in an exceedingly high viscosity for melt-electrospinning. In addition, the absence of NaCl in the melt-electrospun PCL fibers is advantageous. The fibers need not be cleaned to remove additives and can be directly exploited in applications, such as tissue engineering or wound dressing.
DynamFluid: Development and Validation of a New GUI-Based CFD Tool for the Analysis of Incompressible Non-Isothermal Flows
Authors: Redal Héctor , Carpio Jaime , García-Salaberri Pablo A. , Vera Marcos
Published: October 2019

A computational fluid dynamics software (DynamFluid) based on the application of the finite element method with the characteristic-based-split algorithm is presented and validated. The software is used to numerically integrate the steady and unsteady Navier–Stokes equations for both constant-density and Boussinesq non-isothermal flows. Benchmark two-dimensional computations carried out with DynamFluid show good agreement with previous results reported in the literature. Test cases used for validation include (i) the lid-driven cavity flow, (ii) mixed convection flow in a vertical channel with asymmetric wall temperatures, (iii) unsteady incompressible flow past a circular cylinder, and (iv) steady non-isothermal flow past a circular cylinder with negligible buoyancy effects. The new software is equipped with a graphical user interface that facilitates the definition of the fluid properties, the discretization of the physical domain, the definition of the boundary conditions, and the post-processing of the computed velocity, pressure and temperature fields.
Multi-Scale Microstructure Investigation for a PM2.5 Air-Filter Efficiency Study of Non-Woven Polypropylene
Authors: Lam Tu-Ngoc , Wu Chen-Hsien , Huang Sheng-Hsiu , Ko Wen-Ching , Huang Yu-Lih , Ma Chia-Yin , Wang Chun-Chieh , Huang E-Wen
Published: October 2019

A N95 face-piece respirator and a 3M air filter composed of non-woven polypropylene filter material were investigated for their multi-scale microstructure and resulting filtration performance. Filtration mechanisms of each system are found and quantified. Both media showed a gradually decrease of the most penetrating particle size with respect to an increase in face velocity or surface charge density. Increasing the face velocity and porosity dramatically degraded the collection efficiency in the 3M filter rather than in the N95 system. We exploited three-dimensional X-ray tomography to characterize the morphological and geometrical properties of the fiber arrangement and deposition of aerosol on the fiber surface. Tuning the most predominant material parameters to achieve a precedence in lower pressure drop or higher collection efficiency in a specifically captured particle size range is of great requisite to a peculiar application of the filter media.
Uncertainty Assessment in Multitemporal Land Use/Cover Mapping with Classification System Semantic Heterogeneity
Authors: Zhang Xiaokang , Shi Wenzhong , Lv Zhiyong
Published: October 2019

Land use/cover (LUC) data are commonly relied on to provide land surface information in a variety of applications. However, the exchange and joint use of LUC information from different datasets can be challenging due to semantic differences between common classification systems (CSs). In this paper, we propose an uncertainty assessment schema to capture the semantic translation uncertainty between heterogeneous LUC CSs and evaluate the data label uncertainty of multitemporal LUC mapping results caused by uncertainty propagation. The semantic translation uncertainty between CSs is investigated using a dynamic semantic reference system (DSRS) model and semantic similarity analysis. An object-based unsupervised change detection algorithm is adopted to determine the probability of changes in land patches, and novel uncertainty metrics are proposed to estimate the patch label uncertainty in LUC maps. The proposed uncertainty assessment schema was validated via experiments on four LUC datasets, and the results confirmed that semantic uncertainty had great impact on data reliability and that the uncertainty metrics could be used in the development of uncertainty controls in multitemporal LUC mapping by referring to uncertainty assessment results. We anticipate our findings will be used to improve the applicability and interoperability of LUC data products.