bluuebunny/crossref_metadata_2025 huggingface dataset:
Füße als Repräsentanten des Körpers
Authors: Marquardt Hanne
Published: June 2017

Komplementäre Therapiemethoden sind bei vielen Patienten beliebt, obwohl man die Kosten dafür nicht von der Krankenkasse erstattet bekommt. Die Reflexzonentherapie am Fuß gehört zu diesen Behandlungsformen, eine uralte indianische Heilmethode, die im 20. Jahrhundert ihren Weg in die westliche Welt fand.
Impulse für periphere Nerven
Authors: Grünewald Katja , Jünemann Lana
Published: June 2017

Das Guillain-Barré-Syndrom ist selten: Pro Jahr erkranken 1–2 Personen pro 100.000 Einwohner. In Deutschland sind das jährlich zirka 800–1.200 Neuerkrankungen. Männer trifft es häufiger als Frauen. Oft kommt es zur Spontanregeneration. Doch Therapie ist wichtig, damit die Patienten in ihren Alltag zurückkehren können. Lesen Sie, wie Physiotherapie die Rekonvaleszenz unterstützen kann.
Die richtigen Worte finden
Authors: Rose Anke
Published: June 2017

Ob Physiotherapie wirkt, hängt nicht alleine davon ab, ob man richtig Hand anlegt. Die Fähigkeit des Therapeuten, mit dem Patienten zu kommunizieren, spielt ebenfalls eine bedeutende Rolle. Was aber muss der Physiotherapeut über Kommunikation wissen? Und welche Regeln gilt es zu beachten, will man seine Patienten optimal behandeln? In diesem Artikel erhalten Sie Einsicht in Kommunikationsprozesse, die Sie bei der Therapie unterstützen.
Therapie mit Köpfchen
Authors: Thal Stefan
Published: June 2017

Zirka ein Sechstel aller Menschen leidet unter chronischen Kopfschmerzen. Sie führen nicht selten zu verminderter Lebensqualität und zu regelmäßigem Medikamentenkonsum. Zudem sind die volkswirtschaftlichen Kosten beträchtlich. Physiotherapie hilft, Schmerzen zu lindern.
Training & Therapie fürs lädierte Knie
Authors: Steverding Mike
Published: June 2017

Sportler fürchten sie am meisten – die Kreuzbandruptur. Denn sie wissen, dass der Heilungsprozess langwierig sein kann. Ziel der Reha muss sein, die Kniestabilität optimal wiederherzustellen. Eine Aufgabe für Physiotherapeuten, die als Bewegungsspezialisten den Patienten während der Rekonvaleszenz betreuen. Mike Steverding schreibt für physiopraxis über ein modernes Therapie- und Trainingskonzept.
Tod auf der Behandlungsbank
Authors: Lenz Sonja
Published: June 2017

Eine schreckliche Vorstellung: Während der Behandlung beim Physiotherapeuten stirbt ein Patient. Womöglich gar noch durch die Schuld des Therapeuten. Zum Glück passiert das nicht oft und seltener als bei den Ärzten. Doch wenn ein Todesfall eintrifft, ermittelt die Polizei und es kann zu Schadenersatzforderungen kommen.
Qualität sichern mit Leitlinien
Authors: Zietz Dörte
Published: June 2017

Leitlinien waren von Physiotherapeuten lange Zeit unbeachtet. Erst die Leitlinie zur Behandlung von Hemiparese der DGNKN (Deutsche Gesellschaft für Neurotraumatologie und klinische Neurorehabilitation) entfachte eine rege Diskussion in der Physiotherapie. physiopraxis-Autorin Dörte Zietz fasst zusammen, was eine Leitlinie ist, wie sie entsteht und wie die Physiotherapie von Leitlinien profitieren kann.
Ein Quadratmeter voll Wissenschaft
Authors: Zillessen Anke
Published: June 2017

Physiotherapie-Forschung ist im Kommen – auch in Deutschland. Damit Studienergebnisse ihren Weg in die Praxis finden, müssen Forscher sie öffentlich zur Diskussion stellen. Eine Möglichkeit dazu ist ein wissenschaftliches Poster. Wie ein wirkungsvolles Poster aussieht? Dazu gibt es Tricks und Regeln.
Von Knetmäusen und Kittelkaisern
Authors: Kübler Elisabeth
Published: June 2017

Physiotherapeuten haben hin und wieder den Eindruck, Klinikärzte wüssten wenig über die Behandlungsmöglichkeiten der Physiotherapie Bescheid. Eine Folge ist das Gefühl von mangelnder beruflicher Akzeptanz. Die Klinik – ein Spannungsfeld zweier Professionen, in dem jedoch der Widerstand abzunehmen scheint.
Die kleinen Helfer
Authors: Koller Fritz
Published: June 2017

Aus vielen Physiotherapie-Praxen ist sie nicht wegzudenken: Software, die bei der Verwaltung und Organisation der Praxis hilft und die Abrechnung mit den Krankenkassen vorbereitet. Jeder, der sich für den PC in der Praxis entscheidet, hat die Qual der Wahl unter den verschiedenen Programmen: Je teurer, desto funktionsreicher und komfortabler. Doch nicht jeder braucht den Mercedes unter den Praxis-Programmen.
Werbung zum Mitnehmen
Authors: Kamenik Julia
Published: June 2017

Für Praxisinhaber lohnt es sich, Einnahmequellen außerhalb ärztlicher Verordnungen weiter auszubauen. Dies geht allerdings nur, wenn der Patient auch von den Angeboten erfährt. Dabei hilft ein gut gemachter Praxisflyer, der den Patienten einen Überblick über die Praxis und ihre Leistungen gibt.
Von Arnika bis Voltaren
Authors: Wilke Monika
Published: June 2017

Salben tragen zur Genesung von Patienten bei. Bei Hautkrankheiten beispielsweise ist der heilende Effekt unumstritten. Aber auch für Beschwerden im Bewegungsapparat gibt es eine große Auswahl an Präparaten. Ob sie helfen und welche empfehlenswert sind, erklärt die Apothekerin Monika Wilke. Denn die Patienten fragen zu diesem Thema nicht nur ihren Arzt oder Apotheker, sondern auch den Physiotherapeuten.
Physiotherapie in Peru
Authors: Neubauer Ingeborg , Jahn Heiko
Published: June 2017

Der Schönheit Perus stehen Armut und spärliche Gesundheitsversorgung gegenüber. Auf ihrer Reise durch Peru begaben sich die Physiotherapeuten Ingeborg Neubauer und Heiko Jahn nicht nur auf die Spuren der Inkas. Sie behandelten auch behinderte Kinder und erkundeten Gesundheitssystem und Physiotherapie des Andenstaats.
Regionaltreffen: Austausch vor Ort
Authors: Neumann Sabine
Published: June 2017

Viele Berufsgruppen treffen sich mehr oder weniger regelmäßig zu so genannten „Stammtischen”, bei denen sie den Austausch pflegen. Auch Physiotherapeuten kommen regelmäßig regional zusammen – teils organisiert und unterstützt von Verbänden, teils aus eigenem Antrieb.
Schweizer Berufsverband
Authors: Hruschka Simone
Published: June 2017

Trotz ihrer drei Sprachen organisieren sich die Schweizer Physiotherapeuten in einem gemeinsamen Berufsverband. Mit Hilfe des Verbandes ist seit Mai 2004 die Akademisierung der Physiotherapie in der gesamten Schweiz auf den Weg gebracht. Bei Umsetzung und Organisation der Studiengänge können sich die Zuständigen auf die Unterstützung des Verbandes verlassen – und nicht nur dort.
Wahrnehmung im Alltag schulen
Authors: Pott Claudia
Published: June 2017

In physiopraxis 6/09 erschien ein Artikel, der Hintergrundwissen zu Wahrnehmungsstörungen bot und der deren Ursachen sowie die Therapie auf Funktionsebene beschrieb. Hier lernen Sie nun mithilfe eines Fallbeispiels Therapieinterventionen auf Aktivitäts- und Partizipationsebene kennen.
The Thrombostat System A Useful Method to Test Antiplatelet Drugs and Diets
Authors: Kratzer Michael , Negrescu Emil , Hirai Azan , Yeo Young , Petra Franke , Siess Wolfgang
Published: June 2017

The use of platelet inhibitory drugs, like aspirin, has resulted in a significant reduction of thrombotic complications in primary and secondary prevention of heart attacks. To find more effective substances or better drug combinations, inhibition of primary hemostasis in vitro (Thrombostat system) was investigated, with different drugs and fish diet, using small samples (1 ml) of anticoagulated (Na- citrate 3.8%, 1/9) human blood. Results: 1. In the presence of 1mM aspirin, which had no effect on bleeding volume, only 0.6 nM iloprost were necessary to show a 50% inhibition, in contrast to 2.5 μM without aspirin. 2. At aspirin concentrations of 1 mM, 50% inhibition of primary hemostasis could be achieved with 20 μM SIN-I, or with 7 μM SIN-l together with iloprost (500 pM). The same effect was seen only with very high doses of SIN-l (1000 μM) alone. 3. For 50% inhibition of primary hemostasis in vitro, RGDS concentrations were reduced from 250 μM to 160 μM when blood was pretreated with 1 mM aspirin and to 75 μM when 500 pM i1oprost were added additionally. 4. Japanese fishermen (eating 270 g fish/day) demonstrated significantly longer in-vivo bleeding times and in-vitro bleeding volumes (6.49 min/224 μI), respectively, as compared to Japanese farmers (90g fish/day, 4.85 min/137 μI). 5. In Japanese subjects in-vivo bleeding times correlated with in-vitro bleeding volumes (0.69). The Thrombostat system proved to be a sensitive method to detect synergistic effects of various antiplatelet drugs in vitro and of a platelet inhibitory diet ex vivo.
Therapeutic Use of Phospholipids in Thrombocytopenic or Thrombocytopathic Patients
Authors: Dietrich Gerald , Söhngen Dietmar , Kretschmer Volker
Published: June 2017

Eight thrombocytopenic/pathic patients received an intravenous infusion of phospholipids. In vitro bleeding test (Thrombostat 4000), thrombelastography, and resonance thrombography were performed in order to show the hemostatic effect. In none of the cases did phospholipids exert an effect comparable to platelet transfusion. Two patients, brother and sister, had a severe anaphylactoid reaction after the administration of phospholipids.
Nach Feierabend Krankenschwester – Berufstätig mit behindertem Kind
Authors: Ospelt Nina
Published: June 2017

Mutter sein und arbeiten – das verlangt Organisationstalent. Besonders, wenn das Kind behindert ist und intensive Betreuung braucht. Sozialleistungen und Hilfsmittel gibt es viele. Doch manche Eltern sind verunsichert: Was steht uns zu und wo finden wir Hilfe?
Vertiefung - Konservative Therapie für Sportler mit Knorpelschaden
Authors: Wondrasch Barbara , Aldrian Silke
Published: June 2017

Norwegisches Triple Wie Patienten mit Knorpelschäden im Kniegelenk nach einem
dreimonatigen Rehabilitationsprogramm den Alltag wieder problemlos meistern konnten,
untersuchte Barbara Wondrasch gemeinsam mit einer norwegischen Arbeitsgruppe in der Oslo
CARE Study. Für die Sportphysio stellt sie den Rehabilitationsprozess vor. Das Akronym
CARE steht für Cartilage active Rehabilitation and Education.
Erstversorgung am Spielfeldrand (Teil 1)
Authors: Kautz Axel , Sieven Rainer
Published: June 2017

First Aid Was tun, wenn zwei Fußballspieler beim Köpfen zusammenstoßen und der
eine bewusstlos am Boden liegen bleibt oder im Handballtraining eine Spielerin plötzlich
stark aus der Nase blutet? Im Falle einer Verletzung wird der Sportphysiotherapeut zum
Ersthelfer, der die notwendigen Maßnahmen einleitet, bis der Arzt vor Ort ist. Dabei ist
der korrekte Umgang mit den Materialien aus dem Betreuerkoffer enorm wichtig und sollte
regelmäßig geübt werden.
Das Kollektiv
Authors: Bleher Christian
Published: June 2017

Sie sind das Team hinter dem Team Drei Physiotherapeuten arbeiten an Bändern, Sehnen,
Muskeln und Gewebe der schwarz-gelben Erfolgsmaschine. Zu Saisonbeginn empfingen sie
„Sportphysio“ zwischen zwei Trainingseinheiten und gaben Einblicke in ihr Handwerk.
Zielorientierung von muskuloskeletal betroffenen Patienten als motivationsfördernde Maßnahme zur Verbesserung des ambulanten Therapieerfolgs
Authors: Baier J. , Rucker A.M.L. , Landenberger M.
Published: June 2017

Hintergrund: Die Wichtigkeit einer erhöhten Therapiemotivation für den Therapieerfolg wurde schon mehrfach bestätigt. Als motivationsunterstützende Maßnahme bietet sich die Zielorientierung der Patienten an.

Ziel: Das Ziel bestand in der Überprüfung der Überlegenheit einer gemeinsamen Zielvereinbarung zwischen Patienten und behandelnden Physiotherapeuten einschließlich regelmäßiger Erfolgskontrollen hinsichtlich des Therapieerfolgs gegenüber einer Standardtherapie ohne spezielle Zielorientierung.

Methode: Die Wirksamkeit der Zielorientierung wurde über eine multizentrisch durchgeführte Kontrollstudie im Nonequivalent Control Group Design überprüft. Die Studienpopulation umfasste in 2 Gruppen aufgeteilte 128 ambulant behandelte Patienten mit muskuloskeletalen Beschwerden an der unteren Extremität. Die Kontrollgruppe (KG) lieferte die Referenzwerte für den Vergleich mit der Interventionsgruppe (IG). Die IG erhielt in der 1. Behandlungseinheit ein Gespräch zur Zielorientierung. Die vereinbarten Therapieziele wurden nach den SMART-Regeln schriftlich festgehalten und einmal wöchentlich hinsichtlich der erzielten Fortschritte überprüft. Primäres Outcome war die Leistungsfähigkeit beim Treppensteigen mittels des Stair Climb Power Test (SCPT). Sekundäre Endpunkte waren die Schmerzlinderung und die Verbesserung der Gelenkbeweglichkeit. Nicht eingehaltene Behandlungstermine ließen einen Rückschluss auf die Motivationslage des Patienten im Sinne der Adhärenz zu.

Ergebnisse: Beide Gruppen verbesserten bis Behandlungsabschluss ihre Eingangswerte. Im primären Outcome (SCPT) zeigte sich zwar ein deutlicher, jedoch statistisch nicht signifikanter Interventionsvorteil. Die Chance auf eine klinisch relevante Schmerzlinderung war in der IG 2,5-fach höher, der Gewinn zugunsten ihrer Gelenkmobilität signifikant höher. Aufgrund der annähernd gleichen Termintreue bestätigte sich eine Aktivierung der Therapiemotivation nicht.

Schlussfolgerung: Die Studie weist auf ein Verbesserungspotenzial von physiotherapeutischen Behandlungsergebnissen für ambulant behandelte Patienten mit Störungen am Bewegungsapparat hin, wenn diese aktiv in die Zielplanung eingebunden werden. Allerdings ergab sich kein Nachweis für eine durch die Intervention aktivierte Therapiemotivation. Die gute Akzeptanz der Therapeuten bestätigt das Konzept als praktikable und wenig zeitintensive Maßnahme.
Prevention of Colorectal Neoplasia
Authors: Dolejs Scott , Gayed Benjamin , Fajardo Alyssa
Published: June 2017

Colorectal cancer (CRC) is one of the leading causes of cancer-related morbidity and mortality worldwide. There are well-established screening protocols involving fecal testing, radiographic, and endoscopic evaluations that have led to decreased incidence and mortality of CRC in the United States. In addition to screening for CRC, there is interest in preventing colorectal neoplasia by targeting the signaling pathways that have been identified in the pathway of dysplasia progressing to carcinoma. This review will detail the efficacy of multiple potential preventative strategies including lifestyle changes (physical activity, alcohol use, smoking cessation, and obesity); dietary factors (dietary patterns, calcium, vitamin D, fiber, folate, and antioxidants and micronutrients); and chemopreventive agents (nonsteroidal anti-inflammatory drugs, statins, metformin, bisphosphonates, and postmenopausal hormonal therapy).
Genetic Testing for Polyposis Syndromes
Authors: Pyrtel Khateriaa
Published: June 2017

Colorectal cancer is the third most common cancer diagnosed in the United States with up to 3% of cases being attributable to a hereditary polyposis syndrome. Established diagnostic and/or testing criteria exist for many of the recognized polyposis syndromes and are an important tool in guiding physicians in the identification of individuals who may benefit from referral to a cancer genetics service for hereditary cancer risk assessment. A formal hereditary cancer risk assessment supports fulfillment of obligations for standard of care, as well as minimizes the negative outcomes that may occur in the absence of informed consent for genetic testing. The implications of a diagnosis may extend beyond the individual patient to include at-risk relatives, and as such, much emphasis should be placed on identifying the most informative individual in a family in which to initiate testing. Advances in our understanding of genes associated with hereditary polyposis and the increasing use of testing that relies on next-generation sequencing technologies may lead to the increased likelihood of a genetic diagnosis; however, in those individuals without a genetic diagnosis whose histories remain concerning for hereditary polyposis, knowledge of family history may inform strategies for early detection and prevention.
Serrated Polyps and Serrated Polyposis Syndrome
Authors: Ashburn Jean , Plesec Thomas , Kalady Matthew
Published: June 2017

Colorectal serrated polyps are intermediate lesions in the serrated neoplastic pathway, which account for up to 30% of colorectal cancers. This pathway is biologically distinct from the adenoma-to-carcinoma sequence, with associated cancers exhibiting mutations in the BRAF oncogene, DNA promoter hypermethylation, and microsatellite instability. An evolving understanding of these unique lesions has led to the development of a more accurate classification, improved endoscopic identification, and tailored clinical management guidelines. This article reviews serrated polyps and serrated polyposis syndrome.
Iridium-Catalyzed Intramolecular Oxidative Cyclization of Alkenyl Amides and Alkenoic Acids
Authors: Nishimura Takahiro , Nagamoto Midori , Yorimitsu Hideki
Published: June 2017

An iridium/dppf complex efficiently catalyzed the oxidative cyclization of N-sulfonyl alkenyl amides and alkenoic acids. Electron-deficien­t alkenes were effective as sacrificial hydrogen acceptors. High selectivity of the oxidative cyclization over the competing addition reaction has been realized by the use of NaI as an additive.
Chemoselectivity in Esterification Reactions – Size Matters after All
Authors: Helberg Julian , Marin-Luna Marta , Zipse Hendrik
Published: June 2017

The reaction of carboxylic acid chlorides with secondary alcohols carrying either flexible alkyl or rigid aryl substituents was studied through a series of competition experiments. Aliphatic acid chlorides react preferentially with the aryl-substituted alcohols, while acid chlorides derived from aromatic carboxylic acids react with very low selectivity. Catalysis by 9-azajulolidine (TCAP) increases the selectivity strongly, while solvent and temperature effects are only moderate. The size of the alcohol substituents seems to impact selectivities only for rigid aryl substituents, and highest selectivities have been found for 1-(1-pyrenyl)ethanol.
Enantioselective Additions of Stabilized Carbanions to Imines Generated from α-Amido Sulfones By Using Lipophilic Salts of Chiral Tris(1,2-diphenylethylenediamine) Cobalt(III) Trications as Hydrogen Bond Donor Catalysts
Authors: Joshi Hemant , Ghosh Subrata , Gladysz John
Published: June 2017

The enantiopure salt ∆-[Co((S,S)-dpen)3]3+ 2Cl–BArf
– [BArf = B(3,5-C6H3(CF3)2)4] is an effective hydrogen bond donor catalyst (10 mol%, r.t., CH2Cl2) for enantioselective additions of dialkyl malonates to Boc-derivatized aryl imines generated from sulfones [ArCH(SO2Ph)NHBoc] in the presence of K2CO3 (ten examples, 91–97% isolated yields, 87–99% ee). The diastereomeric salt Λ-[Co((S,S)-dpen)3]3+ 2Cl–BArf20
– [BArf20
– = B(C6F5)4
–] is similarly applied to additions of nitroalkanes (four examples, 89–93% isolated yields, 79–91% ee). Precautions to exclude air or moisture are unnecessary.
HYdroxychloroquine to Improve Pregnancy Outcome in Women with AnTIphospholipid Antibodies (HYPATIA) Protocol: A Multinational Randomized Controlled Trial of Hydroxychloroquine versus Placebo in Addition to Standard Treatment in Pregnant Women with Antiphospholipid Syndrome or Antibodies
Authors: Schreiber Karen , Breen Karen , Cohen Hannah , Jacobsen Soren , Middeldorp Saskia , Pavord Sue , Regan Lesley , Roccatello Dario , Robinson Susan , Sciascia Savino , Seed Paul , Watkins Linda , Hunt Beverley
Published: June 2017

Women with antiphospholipid antibodies (aPL) are at risk of adverse pregnancy outcomes, including recurrent first-trimester pregnancy loss and late pregnancy complications such as preeclampsia, HELLP (hemolysis, elevated liver enzyme levels, and low platelet levels) syndrome, premature delivery, intrauterine growth restriction, placental abruption, and intrauterine death. Current standard care in obstetric antiphospholipid syndrome includes aspirin and heparin and has resulted in live-birth rates of approximately 70%. However, 30% continue to have pregnancy complications. Hydroxychloroquine (HCQ) is suggested as a new treatment approach, but no randomized controlled trials (RCTs) have assessed its efficacy. This study aims to assess pregnancy outcome in women with aPL treated with HCQ versus placebo in addition to standard treatment. The HYdroxychloroquine to improve Pregnancy outcome in women with AnTIphospholipid Antibodies (HYPATIA) study is a phase IV multicenter RCT, in which pregnant women with persistent aPL will receive either HCQ or placebo in addition to their usual medication. The primary endpoint is a composite of aPL-related adverse pregnancy outcomes: one or more pregnancy loss(es) (either < 10 or > 10 weeks of gestation) and premature birth before 34 weeks due to any of the following preeclampsia, eclampsia, or recognized features of placental insufficiency. The HYPATIA study is expected to provide evidence on the effect of HCQ in pregnant women with persistent aPL.
Hemostatic Complications in Renal Transplantation
Authors: Antonucci Emilia , Zanazzi Maria , Poli Daniela
Published: June 2017

Chronic kidney disease (CKD) represents the irreversible loss of the excretory and homeostatic functions of the kidney. Renal transplantation is the preferred treatment for patients with advanced CKD. Despite the availability of more effective immunosuppressive drugs and the improvements in surgical techniques, the development of complications can compromise early and long-term outcomes of renal transplantation. In particular, bleeding and thrombotic disorders can have impact on patient and graft survival. Risk stratification, early diagnosis, and appropriate interventions are critical to the management of these complications. Renal arterial and vein thrombosis are the most common vascular complications in the early phase after transplantation, whereas renal artery stenosis is a late event mainly related to surgery. Standard heparin thromboprophylaxis should be adopted in the perioperative period. Among renal transplant recipients, a high risk of venous thromboembolism (VTE) is reported. This risk persists long after transplantation, and patients with a previous episode of VTE are also at high risk for recurrence. An extended anticoagulant treatment should be considered, balancing the bleeding risk in a given patient. To date, the use of vitamin K antagonists remains preferred, given the risk of pharmacological interference with immunosuppressive agents and the renal metabolism of direct oral anticoagulants. In this review, bleeding and thrombotic complications of renal transplantation are described, and recommended thromboprophylaxis is discussed.
Hemostatic Complications in Hepatobiliary Surgery
Authors: Bos Sarah , Bernal William , Porte Robert , Lisman Ton
Published: June 2017

Hepatobiliary surgery is a well-known risk factor for thrombotic complications but is also associated with substantial perioperative blood loss. Given the central role of the liver in hemostasis, hepatobiliary surgery is frequently accompanied by complex changes in the hemostatic system. Increasing knowledge of these changes has resulted in an improved understanding of the etiology of some of the hemostatic complications. In the early postoperative period a prolongation of conventional coagulation test times, such as the prothrombin time, is frequently seen. Together with a decreased platelet count, this suggests a hypocoagulable state. The concomitant decline of anticoagulant factors and development of a von Willebrand factor/ADAMTS13 (a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13) imbalance, however, suggest a hypercoagulable state, potentially contributing to the risk of thromboembolism. Postoperative thromboprophylaxis should be initiated early to avoid thrombosis, and intensified prophylaxis might benefit high-risk patients. The risk of hemorrhagic complications during hepatobiliary surgery has diminished over time, mainly due to improved surgical and anesthesiological techniques. However, bleeding can still be profound in individual patients and is difficult to predict using (global) hemostasis tests. A restrictive transfusion and fluid infusion policy to maintain a low central venous pressure is crucial in prevention of perioperative bleeding. However, when active bleeding occurs, proactive prohemostatic management is required.
Syphilis in Pregnancy and Congenital Syphilis: Reality in a Portuguese Central University Hospital
Authors: Magalhães Magda , Basto Lígia , Areia Ana Luísa , Franco Sofia , Malheiro Maria Eugénia , Afonso Maria Eulália , Moura Paulo
Published: June 2017

Purpose To evaluate maternal-fetal surveillance and follow-up of infants at risk for congenital syphilis (CS).

Methods Retrospective cohort study in a Portuguese Tertiary Referral Hospital. The main inclusion criterion was a positive syphilis serology. The study included all pregnant women that delivered in our hospital between January 2004 and December 2013. The neonates were classified according to their probability of infection based on the Centers for Disease Control and Prevention guidelines.

Results Among the 27 pregnancies at risk for CS, 48.2% (n = 13) of the women had a diagnosis during the 1st trimester, and the median gestational age at the end of the treatment was 28 weeks. Inadequate treatment was noted in 44.4% (n = 12) of the women. Adverse pregnancy outcomes were observed in 30.8% of the cases (n = 8), 5 of which had been adequately treated. We found 2 (7.7%) cases with “proven or highly probable CS,” 10 (38.5%) with “possible CS,” 12 (46.1%) with “less likely CS,” and 2 (7.7%) with “unlikely CS.” Among the infants, the treatment was successful, except for 1 neurosyphilis case.

Conclusion This study highlights many of the difficulties/concerns encountered in the maternal-neonatal management of syphilis. We highlight the importance of assuring the early detection of the infection as a way of guaranteeing the timely treatment, as well as a good compliance to the treatment and follow-up through a more efficient pregnant women surveillance network.
Analysis of Patients’ X-ray Exposure in 146 Percutaneous Radiologic Gastrostomies
Authors: Petersen Tim-Ole , Reinhardt Martin , Fuchs Jochen , Gosch Dieter , Surov Alexey , Stumpp Patrick , Kahn Thomas , Moche Michael
Published: June 2017

Purpose Analysis of patient´s X-ray exposure during percutaneous radiologic gastrostomies (PRG) in a larger population.

Materials and Methods Data of primary successful PRG-procedures, performed between 2004 and 2015 in 146 patients, were analyzed regarding the exposition to X-ray. Dose-area-product (DAP), dose-length-product (DLP) respectively, and fluoroscopy time (FT) were correlated with the used x-ray systems (Flatpanel Detector (FD) vs. Image Itensifier (BV)) and the necessity for periprocedural placement of a nasogastric tube. Additionally, the effective X-ray dose for PRG placement using fluoroscopy (DL), computed tomography (CT), and cone beam CT (CBCT) was estimated using a conversion factor.

Results The median DFP of PRG-placements under fluoroscopy was 163 cGy*cm2 (flat panel detector systems: 155 cGy*cm2; X-ray image intensifier: 175 cGy*cm2). The median DLZ was 2.2 min. Intraprocedural placement of a naso- or orogastric probe (n = 68) resulted in a significant prolongation of the median DLZ to 2.5 min versus 2 min in patients with an already existing probe. In addition, dose values were analyzed in smaller samples of patients in which the PRG was placed under CBCT (n = 7, median DFP = 2635 cGy*cm2), or using CT (n = 4, median DLP = 657 mGy*cm). Estimates of the median DFP and DLP showed effective doses of 0.3 mSv for DL-assisted placements (flat panel detector 0.3 mSv, X-ray image converter 0.4 mSv), 7.9 mSv using a CBCT – flat detector, and 9.9 mSv using CT. This corresponds to a factor 26 of DL versus CBCT, or a factor 33 of DL versus CT.

Conclusion In order to minimize X-ray exposure during PRG-procedures for patients and staff, fluoroscopically-guided interventions should employ flat detector systems with short transmittance sequences in low dose mode and with slow image frequency. Series recordings can be dispensed with. The intraprocedural placement of a naso- or orogastric probe significantly extends FT, but has little effect on the overall dose of the intervention. Due to the significantly higher X-ray exposure, the use of a CBCT as well as PRG-placements using CT should be limited to clinically absolutely necessary exceptions with strict indication.

Key Points 

Citation Format
Schädigung von mikrochirurgischen Instrumenten durch Aufbereitung in einer Zentralsterilisation
Authors: Berto Raphaela , Strutz Jürgen
Published: June 2017

Jedes Jahr werden in Krankenhäusern Risikomeldungen zu Verunreinigungen, Korrosion, Deformation oder vorzeitigem Verschleiß von
Medizinprodukten gemacht. Zu den Auswirkungen des Aufbereitungsprozesses auf die Qualität und Haltbarkeit empfindlicher und sehr feiner
Instrumente gibt es bisher sehr wenige Daten. Diese Arbeit untersucht, ob und gegebenenfalls in welchem Umfang mikrochirurgische Instrumente
durch den Aufbereitungsprozess geschädigt werden.

Material und Methoden Gegenstand der Untersuchung waren 22 mikrochirurgische Instrumente aus der Stapeschirurgie. Die fabrikneuen
Instrumente zweier unterschiedlicher Hersteller A und B wurden jeweils 30 Mal einem Aufbereitungsprozess unterzogen, ohne dass sie jemals
operativ oder anderweitig benutzt wurden. Nach jedem Aufbereitungsprozess wurden die Instrumente makroskopisch und mikroskopisch überprüft.
Die Ergebnisse wurden mittels einer Fotodokumentation dargestellt und auf Basis dieser ausgewertet.

Ergebnisse Bei nahezu allen Instrumenten kam es zu mechanischen Beschädigungen allein durch den Aufbereitungsprozess. In einigen
Fällen wiesen die Instrumente bei der mikroskopischen Sichtkontrolle Verschmutzungen und Flecken auf.

Schlussfolgerung Die Arbeit zeigt auf, wie elementar ein sorgfältiger Umgang mit empfindlichen Instrumenten bei deren Aufbereitung
ist. Sie weist außerdem auf Probleme der bei mikrochirurgischen Instrumenten üblichen Lagerung mit Schutzhülsen hin. Als zukünftige
Alternative sollte über eine statische Lagerung von mikrochirurgischen Instrumenten in speziellen Racks nachgedacht werden.
Tuning static and dynamic properties of FeGa/NiFe heterostructures
Authors: Rementer Colin R. , Fitzell Kevin , Xu Qiang , Nordeen Paul , Carman Gregory P. , Wang Yuanxun E. , Chang Jane P.
Published: June 2017

In this work, the frequency-dependent magnetic properties of sputtered Galfenol/Permalloy (Fe85Ga15/Ni81Fe19 or FeGa/NiFe) magnetic multilayers were examined to tailor their magnetic softness, loss at microwave frequencies, permeability, and magnetoelasticity, leveraging the magnetic softness and low loss of NiFe and the high saturation magnetostriction (λs) and magnetization (MS) of FeGa. The total volume of each material and their ratio were kept constant, and the number of alternating layers was increased (with decreasing individual layer thickness) to assess the role of increasing interfaces in these magnetic heterostructures. A systematic change was observed as the number of bilayers or interfaces increases: a seven-bilayer structure results in an 88% reduction in coercivity and a 55% reduction in ferromagnetic resonance linewidth at the X-band compared to a single phase FeGa film, while maintaining a high relative permeability of 700. The magnetostriction was slightly reduced by the addition of NiFe but was still maintained at up to 67% that of single phase FeGa. The tunability of these magnetic heterostructures makes them excellent candidates for RF magnetic applications requiring strong magnetoelastic coupling and low loss.
A Jeziorski-Monkhorst fully uncontracted multi-reference perturbative treatment. I. Principles, second-order versions, and tests on ground state potential energy curves
Authors: Giner Emmanuel , Angeli Celestino , Garniron Yann , Scemama Anthony , Malrieu Jean-Paul
Published: June 2017

The present paper introduces a new multi-reference perturbation approach developed at second order, based on a Jeziorski-Mokhorst expansion using individual Slater determinants as perturbers. Thanks to this choice of perturbers, an effective Hamiltonian may be built, allowing for the dressing of the Hamiltonian matrix within the reference space, assumed here to be a CAS-CI. Such a formulation accounts then for the coupling between the static and dynamic correlation effects. With our new definition of zeroth-order energies, these two approaches are strictly size-extensive provided that local orbitals are used, as numerically illustrated here and formally demonstrated in the Appendix. Also, the present formalism allows for the factorization of all double excitation operators, just as in internally contracted approaches, strongly reducing the computational cost of these two approaches with respect to other determinant-based perturbation theories. The accuracy of these methods has been investigated on ground-state potential curves up to full dissociation limits for a set of six molecules involving single, double, and triple bond breaking together with an excited state calculation. The spectroscopic constants obtained with the present methods are found to be in very good agreement with the full configuration interaction results. As the present formalism does not use any parameter or numerically unstable operation, the curves obtained with the two methods are smooth all along the dissociation path.
Focal and optical trapping behaviors of radially polarized vortex beam with broken axial symmetry
Authors: Man Zhongsheng , Du Luping , Zhang Yuquan , Min Changjun , Fu Shenggui , Yuan Xiaocong
Published: June 2017

We explore a radially polarized vortex beam with broken axial symmetry under tight focusing conditions. The beam’s three mutually orthogonal polarization components (radial, azimuthal, and longitudinal) are all rotated by an angle of π/2 with respect to the input field in the focal plane. We validate this effect experimentally. Finally, we prove that this effect can be used to transport nanoparticles.
Charge transfer doping of graphene without degrading carrier mobility
Authors: Lu Haichang , Guo Yuzheng , Robertson John
Published: June 2017

Density functional calculations are used to analyze the charge transfer doping mechanism by molecules absorbed onto graphene. Typical dopants studied are AuCl3, FeCl3, SbF5, HNO3, MoO3, Cs2O, O2, and OH. The Fermi level shifts are correlated with the electron affinity or ionization potential of the dopants. We pay particular attention to whether the dopants form direct chemisorptive bonds which cause the underlying carbon atoms to pucker to form sp3 sites as these interrupt the π bonding of the basal plane, and cause carrier scattering and thus degrade the carrier mobility. Most species even those with high or low electronegativity do not cause puckering. In contrast, reactive radicals like -OH cause puckering of the basal plane, creating sp3 sites which degrade mobility.
Ionic liquid ferrofluid interface deformation and spray onset under electric and magnetic stresses
Authors: Jackson Brandon A. , Terhune Kurt J. , King Lyon B.
Published: June 2017

An experimental and computational study is presented on the interfacial dynamics of a colloidal fluid having both high electric conductivity and high magnetic permeability in the presence of simultaneous electric and magnetic stresses on the fluid/air interface. A transient computational model is developed that simultaneously solves the Navier-Stokes equation and Maxwells’ static equations to predict the transient geometry of the fluid subject to electric and magnetic stresses. This model is first applied to predict the onset of spray emission from a capillary needle electrospray source subjected to a magnetic field. The experimentally determined onset of emissions at each magnetic field agreed well with those predicted by the simulation tool. The predictive modeling tool was then applied to analyze the interfacial profile of a sessile droplet subjected to both electric and magnetic fields. The model captured the geometric evolution of the droplet for voltages up to approximately 85% of the critical onset voltage; near the onset, the model slightly overpredicted the droplet deformation. Using the interfacial stress obtained from the modeling tool, a quantitative discussion is made regarding the roles and magnitudes of the electric and magnetic stress components on the lead-up to the emission instability.
Thickness and structure of thin films determined by background analysis in hard X-ray photoelectron spectroscopy
Authors: Cui Yi-Tao , Tougaard Sven , Oji Hiroshi , Son Jin-Young , Sakamoto Yasuhiro , Matsumoto Takuya , Yang Anli , Sakata Osami , Song Huaping , Hirosawa Ichiro
Published: June 2017

We report on the analysis of inelastic backgrounds associated with photoelectron peaks from thin films of Ru on Si using hard X-ray photoelectron spectroscopy (HAXPES) with an X-ray energy of 7939 eV. To extract information on the thickness and morphology of the Ru films, the Tougaard-background-analysis method was used. Consistent results from the analysis of the Si 1s peaks as well as the Ru 2p, 2s peaks to the thicknesses determined with X-ray reflectivity were found. Good agreement was also found for surface topography (the Ru forms islands on the Si surface for film thicknesses <12 nm and covers the complete surface for larger thicknesses) determined by our fitting results and scanning electron microscopy. It is demonstrated that with this method it is possible to obtain information on films up to 150 nm thickness, which corresponds to ∼20 times the inelastic mean free paths (IMFPs). This is larger than the previously reported ∼10 times the IMFP for X-ray photoelectron spectroscopy with conventional X-ray sources owing to the fact that the spectrum can be followed over a larger range of energy-loss. The method can also be used to determine the IMFP if the film thickness is known by another technique and it was applied to determine the IMFP for Ru at 4900 eV (4.3 nm) and 6050 eV (5.3 nm). In addition, some possible applications of the methods are described.
Thermal stability of amorphous Si-rich W silicide films composed of W-atom-encapsulated Si clusters
Authors: Okada Naoya , Uchida Noriyuki , Kanayama Toshihiko
Published: June 2017

We demonstrate the excellent thermal stability of an amorphous film composed of W-atom-encapsulated Si (WSin) clusters with n ≥ 8, formed by thermal deposition using WF6 and SiH4 gas sources. To determine how the structure of the constituting clusters affects the thermal stability of the film, we also prepared films containing unencapsulated WSin clusters in which the W atom was not fully encapsulated in the Sin cage, with n ≤ 7. The effect of annealing was investigated by Raman scattering and optical absorption measurements with repeated 10-min isochronal annealing in a N2 atmosphere at temperatures ranging from 500 to 1100 °C. The films, composed of WSin clusters completely encapsulating W atoms with a uniform composition of n = 12, remained in the same amorphous structure up to 1000 °C, although partial crystallization of Si began at 1100 °C. The stability decreased when the film contained unencapsulated WSin clusters, even with an average film composition of n ≤ 10; partial crystallizations of Si and WSi2 were observed after annealing at 800 °C. Density-functional theory calculations indicate that a structure assembled from three encapsulated WSi12 clusters preserves the bonding topology of the constituting clusters in which Si atoms are strongly bonded, accounting for the high thermal stability of the film composed of encapsulated WSin clusters.
Thermoelectric properties of Si-NiSi2 bulk nanocomposites synthesized by a combined method of melt spinning and spark plasma sintering
Authors: Eaksuwanchai Preeyakarn , Kurosaki Ken , Tanusilp Sora-at , Ohishi Yuji , Muta Hiroaki , Yamanaka Shinsuke
Published: June 2017

Si exhibits high power factor, but its lattice thermal conductivity (κlat) is significantly high, leading to a low thermoelectric figure of merit (ZT) to be around 0.01. Here, we attempted to reduce the κlat of Si with keeping high power factor by dispersing NiSi2 precipitates. Since the lattice parameter of NiSi2 (0.5416 nm) is nearly equal to that of Si (0.5430 nm), it is expected to form coherent interfaces between Si and NiSi2, which would have less effect on the carrier transport to maintain high power factor. The Si/NiSi2 bulk composites with the starting composition of (Si100P3)98Ni2 were synthesized by a combined method of melt spinning and spark plasma sintering. The κlat of the samples clearly decreased while the carrier mobility did not change significantly, leading to the improved ZT value of 0.23 at 1033 K, approximately ∼50% higher than that of a typical n-type bulk Si.
Ion heating and flows in a high power helicon source
Authors: Thompson Derek S. , Agnello Riccardo , Furno Ivo , Howling Alan , Jacquier Rémy , Plyushchev Gennady , Scime Earl E.
Published: June 2017

We report experimental measurements of ion temperatures and flows in a high power, linear, magnetized, helicon plasma device, the Resonant Antenna Ion Device (RAID). Parallel and perpendicular ion temperatures on the order of 0.6 eV are observed for an rf power of 4 kW, suggesting that higher power helicon sources should attain ion temperatures in excess of 1 eV. The unique RAID antenna design produces broad, uniform plasma density and perpendicular ion temperature radial profiles. Measurements of the azimuthal flow indicate rigid body rotation of the plasma column of a few kHz. When configured with an expanding magnetic field, modest parallel ion flows are observed in the expansion region. The ion flows and temperatures are derived from laser induced fluorescence measurements of the Doppler resolved velocity distribution functions of argon ions.
Intermolecular interactions in the condensed phase: Evaluation of semi-empirical quantum mechanical methods
Authors: Christensen Anders S. , Kromann Jimmy C. , Jensen Jan H. , Cui Qiang
Published: June 2017

To facilitate further development of approximate quantum mechanical methods for condensed phase applications, we present a new benchmark dataset of intermolecular interaction energies in the solution phase for a set of 15 dimers, each containing one charged monomer. The reference interaction energy in solution is computed via a thermodynamic cycle that integrates dimer binding energy in the gas phase at the coupled cluster level and solute-solvent interaction with density functional theory; the estimated uncertainty of such calculated interaction energy is ±1.5 kcal/mol. The dataset is used to benchmark the performance of a set of semi-empirical quantum mechanical (SQM) methods that include DFTB3-D3, DFTB3/CPE-D3, OM2-D3, PM6-D3, PM6-D3H+, and PM7 as well as the HF-3c method. We find that while all tested SQM methods tend to underestimate binding energies in the gas phase with a root-mean-squared error (RMSE) of 2-5 kcal/mol, they overestimate binding energies in the solution phase with an RMSE of 3-4 kcal/mol, with the exception of DFTB3/CPE-D3 and OM2-D3, for which the systematic deviation is less pronounced. In addition, we find that HF-3c systematically overestimates binding energies in both gas and solution phases. As most approximate QM methods are parametrized and evaluated using data measured or calculated in the gas phase, the dataset represents an important first step toward calibrating QM based methods for application in the condensed phase where polarization and exchange repulsion need to be treated in a balanced fashion.
Oxidation dynamics of ultrathin GaSe probed through Raman spectroscopy
Authors: Bergeron Alaric , Ibrahim John , Leonelli Richard , Francoeur Sebastien
Published: June 2017

Gallium selenide (GaSe) is a 2D material with a thickness-dependent gap, strong non-linear optical coefficients, and uncommon interband optical selection rules, making it interesting for optoelectronic and spintronic applications. In this work, we monitor the oxidation dynamics of GaSe with thicknesses ranging from 10 to 200 nm using Raman spectroscopy. In ambient temperature and humidity conditions, the intensity of all Raman modes and the luminescence decrease rapidly with moderate exposure to above-gap illumination. Concurrently, several oxidation products appear in the Raman spectra: Ga2Se3, Ga2O3, and amorphous and crystalline selenium. We find that no safe measurement power exists for optical measurements on ultrathin GaSe in ambient conditions. We demonstrate that the simultaneous presence of oxygen, humidity, and above-gap illumination is required to activate this photo-oxidation process, which is attributed to the transfer of photo-generated charge carriers towards aqueous oxygen at the sample surface, generating highly reactive superoxide anions that rapidly degrade the sample and quench the optical response of the material.
On the limit relation for the quantum relative entropy
Authors: Bernád J. Z. , Frigyik A. B.
Published: June 2017

Recently, Diósi et al. introduced a simple, yet very interesting model for reservoirs, in order to study the relationship between thermodynamic entropy production of a system and the corresponding von Neumann entropy (or informatic entropy, as it was called by the authors). They came up with a conjecture about the asymptotic behaviour of the state introduced in the model. The conjecture was proven later by Csiszár et al. In this paper, we give a different interpretation of the original question and extend the result to a collection of more general states.
Post-experimental modelling of grazing systems to improve profit and environmental outcomes using AusFarm
Authors: Broadfoot K. M. , Badgery W. B. , Millar G. D.
Published: June 2017

Assessments of grazing systems are often constrained by the decisions regarding the management of the grazing systems, including stocking rate, and also the seasonal conditions that occur during the assessment period. These constraints have led to sometimes conflicting results about comparisons of grazing management systems. This paper examines 1-, 4- and 20-paddock (1P, 4P and 20P) grazing management systems to determine how the intensity of grazing management on native pastures influences the financial performance of sheep production systems. The performance of the grazing systems, as part of the Orange EverGraze research experiment, was initially examined using the biophysical data over the 4 years of the experiment and then a more detailed analysis over a longer timeframe was undertaken using the AusFarm simulation modelling software. Flexible management strategies to optimise ewe numbers, sale time of lambs, and adjust ewe numbers based on season, were also assessed to determine which management systems are the most profitable and sustainable. There was higher profit for the 20P grazing system than the 1P system during the experiment. However, when stocking rates were held constant at optimum levels and systems were simulated over 40 years, there was no difference between grazing systems. Modelling strategies used to vary stocking rates showed that flexible management options are better based on optimising ewe numbers and the sale time of lambs rather than changing ewe numbers between years. The sustainability of modelled systems was also assessed using frequency of events where the average herbage mass (0.8 t DM/ha) or ground cover (80%) in autumn dropped below levels that are associated with degradation. Degradation events occurred more so with increasing ewe number than lamb sale time. Overall, the most sustainable systems, when considering profitability and environmental issues, had a stocking rate of 4.2 ewes per ha, with lambs sold in February (2 or 18). Higher stocking rates (5.3 ewes/ha) would need to be run for more intensive grazing management to have higher profitability.