bluuebunny/crossref_metadata_2025 huggingface dataset:
Rational frequency range and criteria for diagnosing endogenous fire zones in coal massifs by using the georadiolocation method
Authors: Prostov Sergey M. , Kalaygoroda Vsevolod V. , Shabanov Evgeny A.
Published: September 2024

Relevance. The necessity to improve the accuracy of analysis and prediction of potential fire hazard of rock-coal massifs by using electromagnetic methods of endogenous fire detection. Taking into consideration that the increase in coal temperature changes a number of its parameters, such as dielectric permittivity and electrical resistivity, it is reasonable to use the method of electromagnetic reconnaissance in locating the focus of fire. Aim. To analyze the theoretical and practical knowledge about the anomalies formed in the area of spontaneous combustion and to evaluate the effectiveness of electromagnetic methods for locating the spontaneous combustion zones of a coal massif. Objects. Physical parameters of the ignition zone of the coal massif, such as dielectric permittivity and electrical resistivity, as well as the range of the GPR central frequency, allowing clearly defining the boundaries of the ignited zone. Method. Reviewing the proposed methods of determining the parameters serving for correct location of the fire zone. For GPR it is necessary to determine the center frequency of the standard antenna unit and resolution, then to estimate the rational frequency range of GPR. Results. Allow us to draw conclusions about the methods used to determine the rational range of GPR center frequency – it can be calculated by solving the system of equations of the signal attenuation function and energy potential of GPR, by the experimental value of the target function, including the depth and detail of sounding as a function of frequency, or on the basis of a complex parameter of GPR, including the radiated power of the antenna, the number of accumulations and the reflection coefficient from the boundaries. Taking into account such physical features of the fire zone as drying the rock-angle massif and the shape of the anomalous zone, the rational range of the center frequency for the GPR "OKO-2" was determined.
Regional, local and current forecast of the impact hazard of coal seam sites based on seismic monitoring
Authors: Razumov Egor E. , Prostov Sergey M. , Shabanov Evgeny A.
Published: September 2024

Relevance. Insufficient validity of the quantitative criteria of the regional, local and current forecast of the impact hazard of the coal seams being developed, the absence of algorithms linking the use of geophysical and direct geomechanical methods in forecasting. Aim. To develop a comprehensive method of geodynamic forecasting, including determining the extent of an impact-prone area identified by the results of a regional forecast based on the registration data of the GITS seismic monitoring system, for conducting local and current forecasts of impact hazard by regulatory methods. Object. An array of rocks of the excavation column 4-1-5-7 of the Osinnikovskaya mine during mining operations in the zone of a group of tectonic disturbances and the intersection of advanced workings. Methods. Regional geomechanical forecast by the geophysical method of seismic activity registration (GITS system), local (current) forecast by natural electromagnetic radiation methods (Angel-M equipment) and the output of drilling fines. Results. The paper introduces the results of complex studies in the excavation column 4 1-5-7 of the Osinnikovskaya mine to establish a correlation between seismic activity and the parameters of the stress-strain state of the array. The authors have introduced the concept of integral indicators of the considered parameters IF and Ikσ. They take into account the area of the zone for the i-th range according to the complex parameter of seismic activity F and the coefficient of vertical stresses in the roof of the formation Kσ. It is established that the informative value of the integral indicators is almost twice as high as the informative value of the initial parameters. Experimental nomograms  и  are presented to determine the category "DANGEROUS/NON-DANGEROUS" for the regional forecast of impact hazard according to the GITS seismic monitoring system. The authors developed a general algorithm for predicting the impact hazard during clean-up operations. This algorithm uses an integrated approach that includes a regional forecast for recording seismic activity within the mine field and local forecasting methods, both geophysical and direct, to clarify the boundaries of seismic energy release zones and confirm the category of impact hazard. Thу paper introduces the example of determining the width of the zone of increased seismic energy release in the mine closest to the seismically active zone. The dynamics of the occurrence, development and decrease of the seismic energy release zone in the considered areas in the mine workings is shown. The authors give the examples of the implementation of a local forecast of impact hazard in previously established potentially dangerous areas by methods of recording natural electromagnetic radiation of rocks and by the output of drilling fines.
Geotectonic model of the deep structure of the Zmeinogorsky ore district of Rudny Altai according to geological interpretation of geophysical survey complex
Authors: Egorov Alexey S. , Kalinin Dmitry F. , Sekerina Darya D.
Published: September 2024

Relevance. The relevance of the research of deep structure of the Zmeinogorsky ore district is caused by the search for hidden and poorly manifested pyrite-polymetallic mineralization on the surface within the Rudny Altai minerogenic zone. This task is of particular prognostic interest due to the high searchability of the area on the surface and the prospects for detecting hidden mineralization at deeper horizons. Aim. Geotectonic modeling of structural and material inhomogeneities of the Earth's crust of the Zmeinogorsky ore district based on a comprehensive interpretation of geological and geophysical data with the identification of patterns of localization of hidden and poorly manifested pyrite-polymetallic mineralization on the surface. Objects. Regularities of localization of hidden and poorly manifested pyrite-polymetallic mineralization on the surface within the Zmeinogorsky ore district of the Rudny Altai. Methods. Processing of areal and profile materials of the study of the Rudny Altai, qualitative and quantitative interpretation of heterogeneous geological and geophysical information at the regional and detailed levels. The study of the history of development and geodynamic conditions of the formation of ore-bearing structures of the Zmeinogorsky ore district with the identification of geological and structural prognostic features at depths of practical interest. Results. Based on a comprehensive analysis of heterogeneous geological and geophysical data, the authors have carried out the historical-evolutionary and geodynamic interpretation of the mineragenic structures of the Zmeinogorsky ore district within the Rudny Altai; these materials can be used as the basis for regional forecast constructions using non-standard geological, structural and material (tectonic) signs; the special influence of tectonic events characterizing the situation of the active continental margin with complicating episodes of rifting was verified; the patterns of localization of pyrite-polymetallic ores in volcanogenic-sedimentary rocks were revealed with the justification of a set of predictive criteria.
Effect of secondary processes on the petrophysical properties of sand rock of the tanopchin formation of the Tambey field (Yamalo-Nenets autonomous okrug)
Authors: Zhdanova Yulia Yu.
Published: September 2024

Relevance. Finding the correlation between filtration-capacitive properties and secondary processes helps to identify missed oil and gas deposits. Traditional methods of processing geophysical information are becoming less and less effective, and accordingly there is a need to introduce new techniques for detecting missed hydrocarbon deposits. Aim. To study the effect of secondary processes on the filtration and reservoir properties of rocks in the productive lower strata of the tanopchin formation of the North Tambey license area, located within the Tambey field, using materials from geophysical surveys of wells and core data. Methods. The statistical-correlation interpretation method represents a significant breakthrough in the field of interpretation of well logging data. It allows for a more accurate interpretation of data from existing reservoir studies, which makes it possible to identify productive sections of wells where hydrocarbons could not be detected by traditional methods. Statistical correlation interpretation is carried out on the basis of data from secondary geochemical processes occurring in the formation. The scientific novelty. Identification of the relationship between the intensity of secondary processes and the petrophysical properties of the rocks of the Lower Cretaceous productive horizon of the Tambey field (Yamalo-Nenets autonomous okrug). Results and conclusions. The author has determined the dependence of the filtration-capacitive properties of rocks on the intensity of secondary geochemical processes. It was established that secondary geochemical processes such as carbonatization and pyritization worsen reservoir properties, while kaolinization and pelitization lead to an improvement in the filtration and reservoir properties of reservoir rocks. The paper explains the mechanism of effect of secondary processes on filtration-capacitive properties. Pelitization of potassium feldspars leads to the formation of three-layer clay minerals, which have the largest sorption surface area and cation exchange capacity; as a result, the reservoir capacity increases, which leads to an increase in permeability several times.
Comprehensive research of the distribution of tellurium-bismuth mineralization in the ores of the Abyz and Maleevskoe sulfide deposits (Republic of Kazakhstan)
Authors: Nikolaeva Anastasia N. , Mazurov Alexey K.
Published: September 2024

Abstract. Within the formations of ensimatic and ensialic island arcs in the territory of Central and Northern Kazakhstan, there are more than thirty pyrite deposits enriched in copper, lead, zinc, gold, silver and rare metal mineralization, which is still insufficiently studied. Relevance. The need to replenish information on tellurium-bismuth mineralization in ores of sulfide deposits formed in ensimatic (Abyz deposit) and ensialic (Maleevskoe deposit) island-arc systems, to establish a spatial connection of this type of mineralization with geodynamic conditions and predict the potential for their associated extraction from ore. Aim. To study and compare morphological characteristics, distribution patterns and conditions for the formation of tellurium-bismuth mineralization in ores of pyrite deposits formed in different island-arc geodynamic settings. Methods. Inductively coupled plasma mass spectrometry, mineragraphic and mineralogical analyses, scanning electron microscopy in combination with X-ray spectral microanalysis, Raman spectroscopy, thermobarogeochemical studies. Results. A comparison of the pyrite deposits of the Rudno-Altai and Chingiz-Tarbagatai island arc systems showed many similarities and differences between them. The deposits have a multi-stage formation and a similar mechanism of ore deposition with similar physicochemical conditions for the formation of tellurium-bismuth mineralization. A spatial relationship between Te-Bi mineralization and geodynamic settings was established: for deposits associated with paleooceanic structures, a predominance of the tellurium element is observed, and for continental rifts, a predominance of the bismuth element.
Climate Change Impacts and Risks for Animal Health: Indian Context: A Review
Authors: Suryawanshi Rahul , Thakare Rashmi , Kamat Hrishikesh , Deshmukh Onkar , Shinde Onkar , Alapure Renuka , Kamble Ashutosh
Published: September 2024

Climate change is a widely accepted truth that has impacted all ecosystems and will continue to do so if left unchecked. The effects of some elements have received more attention than others and animals fall into the latter category. Even among the components of climate change impacts on animals, production-related implications have received emphasis. In contrast, the implications on health in general and infectious illnesses in particular, have been overlooked. Despite not being well investigated, it may be predicted that, as with people, climate change, particularly global warming, will significantly impact animal health, both overt and covert. Temperature-related disease, death and animal morbidity during extreme weather events are direct repercussions. Indirect effects follow more complicated pathways and include those resulting from animals¢ attempts to adapt to thermal environments or the influence of climate on microbial populations, the spread of vector-borne diseases, feed and water scarcities, or food-borne diseases and host resistance to infectious agents. It is necessary to develop tools and strategies for an animal illness surveillance system that integrates animal data with appropriate climatic variables. The development and application of methods for integrating climate data with disease monitoring systems is necessary to improve animal illness prevention, mitigation and adaptive responses to heat stress.
Hepatotoxicity of Oral Sub-chronic Exposure to Thiamethoxam and Lambda Cyhalothrin in Rats
Authors: Alsadee Sawsan Agbashee , Mohammed Sameer Abed , Hasan Ahmed Flayyih
Published: September 2024

Background: Thiamethoxam is a synthetic organic insecticide belong to The most significant new class of pesticides created in the last thirty years is neonicotinoids. This study’s objective was to determine the effect of thiamethoxam, lambda cyhalothrin and their combination on biochemical parameters, the levels of free radicals and enzymes activities liver of male. Methods: Forty Rats (150-170 g) were used animals were separated into four groups, each with ten rats. The Gp1 was used as control, the Gp2 was used to study the effect of thiamethoxam for 3weeks, the Gp3 was employed to examine the impact of lambda cyhalothrin for 3 weeks and the Gp4 was used to research the impact of thiamethoxam and lambdacyhalothrin for 3 weeks. Result: Treatment with thiamethoxam (TMX), lambda cyhalothrin (LC) and their combination (TMX+LC) lowered the activities of glutathione s-Trasferase , Superoxide Dismutase, Catalase, Glutathione Peroxidase , Glutathione Reductase and decreased glutathione concentration. increased liver thiobarbituric acid reactive compounds and hydrogen peroxide of liver as compared to control. Rats treated with both TMX and LC showed more pronounced effect. Rats given the treatment showed a substantial drop in protein levels TMX, LC and their combination as compared to control. Treatment with TMX, LC and their combination generated a considerable rise in lactate dehydrogenase and a significant reduction in the activities of alkaline phosphatase, aspartate aminotransferase and alanine aminotransferase in rat liver homogenates. Histological examinations showed changes and this proved the Biochemical disruptions happened as a result of to TMX and/or LC toxicity in rat liver.
A Study on Prevalence and Clinico-pathological Findings Associated with Ascites in Dogs
Authors: Patowary Prerona , Das Arup , Barman Utpal , Hazorika Mousumi , Arif Syed A. , Baruah Aditya , Kalita Manoj Kumar
Published: September 2024

Canine ascites is a common illness with multiple aetiologies. However, the involvement of various etiological factors is making therapeutic management extremely difficult for the clinicians. The present study was conducted on dogs with distension of abdomen at Veterinary Clinical Complex, College of Veterinary Sciences, Assam Agricultural University, Khanapara, Assam, India, to study the prevalence of the disease with respect to primary organ involvement in the pathogenesis of ascites and hemato-biochemical changes. The blood samples from the dogs were collected for hemato-biochemical analysis. Routine blood smear, fecal smear examination, ultrasonography and echocardiography of all the ascetic dogs were carried out to find out the exact etiology of ascites. Out of the total 7788 dogs assessed throughout the period from August, 2022 to January, 2023, 32 dogs (0.41%) developed ascites. The highest prevalence of ascites 53.12% was recorded in the dogs of above 6 years of age and breed wise Labrador breed (34.37%) of dogs were most commonly affected. Most of the ascites cases were found to be largely due to liver diseases (34.37%); 31.25% were due to congestive heart failure, 21.87% due to infectious causes and 12.50% due to kidney disease. The hemato-biochemical analysis revealed anemia, mild leukocytosis, hypoproteinaemia, hypoalbuminemia, hyperbilirubinemia, increased alanine aminotransferase (ALT), aspertate aminotransferase(AST), lactate dehydrogenase(LDH), blood urea nitrogen (BUN) and creatinine level in the ascitic dogs.
Potensi Kawasan Segara Anakan Sebagai Sarana Fieldwork Pada Pembelajaran Geografi Materi Lingkungan Estuari
Authors: Rizal Syah , Sumarmi Sumarmi , Bachri Syamsul , Mutia Tuti , Ismail Alice Sabrina
Published: September 2024

Fieldwork learning is a form of implementing real geography learning to improve students' competence in understanding geosphere phenomena. The various benefits of fieldwork learning require the right tools in its application. The Segara Anakan area with all its appearances and resources has the potential to be used as a means of learning important fieldwork on estuarine environmental material. This study aims to explore the potential and strategy of the Segara Anakan Area as a means of learning geography fieldwork on estuarine environmental material. This research is included in the qualitative descriptive research. The data used are primary data from field observations and secondary data from scientific literature. The analysis used is descriptive analysis to describe the potential of the Segara Anakan Area as a means of learning fieldwork in an estuary environment. The results showed that the Segara Anakan area has objects that can be used as objects of study according to competence and indicators of estuarine environmental material. This fieldwork strategy is carried out by determining the object of study, accessibility, instruments, equipment, and materials to be used during field activities. During the activity, students make observations, collect data, and listen to the teacher explain the object of study. The implementation of fieldwork in the Segara Anakan area has constraints such as time, costs, permits, and threats when carrying out fieldwork.
Pengaruh Model Pembelajaran CORE dengan Metode Problem Posing terhadap Kemampuan Pemecahan Masalah Matematika Siswa Kelas VIII SMP di Lubuklinggau
Authors: Sari Ratna
Published: September 2024

ABSTRACT
 
This study aims to determine the effect of CORE learning model by the method of Problem Posing on mathematical problem solving ability at the eighth grade students of SMP Ar Risalah Lubuklinggau in academic year 2019/2020. The research method used in the form of pure experimentation. The population in this study were all students of class VIII SMP Ar Risalah Lubuklinggau the academic year 2019/2020, which consists of 157 students and a sample is VIII.Ibnu Khaldun as an experimental class and VIII.Ibnu Miskawaih as the control class. Collecting the data in the study used a test about the description. The data were analyzed using t-test. Based on the analysis of t-test with a significant level of = 0.05, obtained thitung (1,81) > ttabel (1,67), so it can be concluded that there is influence learning model CORE method Problem Posing on mathematical problem solving ability at the eighth grade students of SMP Ar Risalah Lubuklinggau in academic year 2019/2020. From the results of post-test the average score of students' mathematical problem solving ability in the experimental class was 23.52 and in the control class was 14.45.
 
Keywords: CORE, Problem Posing, Problem Solving.
 

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ABSTRAK
 
Penelitian ini bertujuan untuk mengetahui pengaruh model pembelajaran CORE dengan metode Problem Posing terhadap kemampuan pemecahan masalah matematika siswa kelas VIII SMP Ar Risalah Lubuklinggau tahun pelajaran 2019/2020. Metode penelitian digunakan berbentuk eksperimen murni. Populasi dalam penelitian ini adalah seluruh siswa kelas VIII SMP Ar Risalah Lubuklinggau tahun pelajaran 2019/2020, yang terdiri dari 157 siswa dan sebagai sampelnya adalah kelas VIII.Ibnu Khaldun sebagai kelas eksperimen dan kelas VIII.Ibnu Miskawaih sebagai kelas kontrol. Pengumpulan data dalam penelitian menggunakan tes soal uraian.. Data yang terkumpul dianalisis menggunakan uji-t. Berdasarkan hasil analisis uji-t dengan taraf signifikan sebesar  = 0,05, diperoleh thitung (1,81) > ttabel (1,67), sehingga dapat disimpulkan bahwa ada pengaruh model pembelajaran CORE dengan metode Problem Posing terhadap kemampuan pemecahan masalah matematika siswa kelas VIII SMP Ar Risalah Lubuklinggau tahun pelajaran 2019/2020. Dari hasil post-test rata-ratas skor kemampuan pemecahan masalah matematika siswa pada kelas eksperimen sebesar 23,52 dan pada kelas kontrol sebesar 14,45.
 
Kata kunci: CORE, Problem Posing, Pemecahan Masalah.
Problem-based learning through lesson study learning community to enhance students' mathematical communication skills
Authors: Susanti Ely , Suparmi Etty , Syahrial Syahrial , Effendi Firman , Sari Puspita , Ningsih Sri Tuti
Published: September 2024

The aim of this research is to describe students' mathematical communication skills by integrating information technology in a collaborative problem-based learning model designed by teachers and lecturers through a lesson study learning community. The research subjects were 36 students in grade tenth (X.4) at SMA Srijaya Negara Palembang in the 2023/2024 academic year. This research is a mix method with quantitative and qualitative techniques. This research has four stages, namely: plan, do, see, and retrospective analysis. The instruments of this research are test questions, observation sheets, and interview guidelines. Data analysis techniques use quantitative and qualitative. Test result data is scored based on a scoring rubric. Observation data is a percentage based on the appearance of indicators. Test and observation data are categorized into five categories, namely: very good, good, enough, less, and poor. Based on the results of data analysis, it was found that students were able to speak language and convey ideas for solutions well. However, there are students who have difficulty expressing concepts and reading mathematical notation both in writing and orally. This low ability is influenced by several factors such as low student activity during learning and discussions, low interest, lack of self-confidence, and from the cognitive aspect it is influenced by low levels of accuracy and habits in solving problems. So, it can be concluded that students' mathematical communication skills after learning using a problem-based learning model and integrating information technology through lesson study learning communities are categorized as enough.
COVID-19 Vaccination in Autoimmune Patients: A Literature Review
Authors: Wardhany Atiqah Nurul , Awalia  , Setiabudi Rebekah J
Published: September 2024

Patients with autoimmune diseases, especially rheumatic diseases, have their own concerns regarding the coronavirus disease 2019 (COVID-19) vaccination. Their concerns are specifically related to the physicological response, side effects, and effectiveness of the COVID-19 vaccination. COVID-19 and autoimmune diseases share some similarities in their clinical manifestations, immune responses, and pathogenic mechanisms. The correlation between COVID-19 vaccination and autoimmune diseases can be attributed to epitope mimicry, where the antigen contained in the vaccine has a structural similarity to self-antigen. The purpose of this literature review was to discuss the various types of vaccines, the side effects of the COVID-19 vaccination, and the effect of autoimmune patients' medication on the administration of the COVID-19 vaccination. According to several articles obtained in this study, most autoimmune patients typically experienced mild to moderate side effects. It was not advised for these patients to stop treatment before receiving the COVID-19 vaccination, as doing so was unlikely to affect the vaccine's effectiveness or the patients' immune response. The condition of the autoimmune patients was what influenced the immune response mediated by antibodies. Therefore, the COVID-19 vaccination must be administered when the patients are in a stable condition. In conclusion, it was determined that there is no restriction preventing autoimmune patients from receiving the COVID-19 vaccination. However, it should be noted that autoimmune patients are not recommended to receive live vaccines.
 
Highlights:

This study reviewed the concerns of autoimmune patients over the side effects of the COVID-19 vaccination on their prescribed medication.
It is advisable for autoimmune patients to refrain from obtaining live-attenuated vaccines because of their potential effect on the immune response.
Shift Work and Associated Health Consequences: A Review
Authors: Burooj Ahmed
Published: September 2024

This literature review aims to examine the complex relationship between engaging in shift work and its subsequent health sequelae, while also shedding light on fields of research that require further investigation. Indexing services (i.e., Scopus and PubMed) were used to identify pertinent studies, prioritizing original research, review articles, and meta-analyses from 2018 to 2023. Papers not published in English or where full-text translation was not available, research conducted solely on non-human populations, as well as proposal and opinion papers, were excluded. Papers published before 2018 and those with a sample size of 50 participants or fewer were also omitted. The author conducted a thorough evaluation of each study to ensure its relevance and significance. After deduplication of the search results and implementation of the exclusion criteria, 51 papers were shortlisted for this review. The keywords used for the literature search were “shift work”, “health”, “night shift”, “cardiovascular”, “circadian, cancer”, “disease”, “dose-response relationship”, and “long working hours”. The results showed that shift work significantly impacts various aspects of health, presenting risks in the areas of cardiovascular health, cancer susceptibility, circadian rhythm, immunity, metabolism, reproductive health, and mental well-being. Shift workers have increased risks for diabetes, hypertension, adverse cardiac events, circadian dysrhythmia, metabolic syndrome, mental health disorders, and even certain types of cancer. Shift work exhibits significant associations with sexual and reproductive dysfunction in both sexes, including elevated risks for miscarriages and preterm birth. In conclusion, the findings underscore the need for comprehensive health interventions and further research to understand the intricate relationships between shift work and long-term health consequences.
 
Highlights:

Disruption of circadian rhythm due to shift work contributes to various health issues, including altered melatonin levels, immune dysfunction, and metabolic disturbances.
There is a critical need for longitudinal studies to explore interventions and workplace policies that can mitigate the adverse health effects of shift work.
Addressing the multifaceted impact of shift work on health requires a holistic approach that considers factors like circadian rhythm optimization, workplace support, and tailored interventions.
Advances in solid-state and flexible thermoelectric coolers for battery thermal management systems
Authors: Wang Lijun , Shi Xiao-Lei , Yue Yicheng , Li Lvzhou , Dong Cuicui , Guan Jianjun , Ding Jianning , Yuan Ningyi , Chen Zhi-Gang
Published: September 2024

Battery thermal management systems (BTMS) play a crucial role in various fields such as electric vehicles and mobile devices, as their performance directly affects the safety, stability, and lifespan of the equipment. Thermoelectric coolers (TECs), utilizing the thermoelectric effect for temperature regulation and cooling, offer unique advantages for BTMS. Compared to traditional cooling techniques, TEC-based BTMS provides precise temperature control, which allows customized adjustment of temperatures in different areas, meeting the strict thermal management demands in various fields. This offers more reliable and efficient thermal management solutions for applications in electric vehicles and mobile devices. Furthermore, flexible TECs can provide more efficient thermal management for flexible batteries. This article timely and extensively explores several solid-state and flexible TEC-based BTMS technologies, including combinations with air cooling, liquid cooling, phase-change cooling, heat pipe cooling, and various cooling composite techniques. Battery heat generation models and the analysis process of TEC-based BTMS are first discussed. An objective evaluation of the advantages and disadvantages of various TEC-based BTMS approaches is provided, along with discussions on reasonable solutions and future development trends, aiming to provide a reference for designing optimal BTMS. In the end, we point out that it is crucial to select appropriate cooling technologies according to user requirements and to combine multiple cooling technologies for meeting thermal management needs in different application scenarios.
Landscape and climatic confinement of settlements of peasant-migrants of the late 19th — early 20th century on the territory of the Odessa district of the Omsk oblast
Authors: Moskovchenko D.V. , Fedorov R.Yu. , Tigeev A.A. , Lonsky A.I. , Slepchenko S.M.
Published: September 2024

The landscape-climatic confinement of villages that were founded in the late 19th — early 20th century by peasant-migrants in the territory of the modern Odessa district of the Omsk oblast has been examined. Trend analysis, which were identified during the integration of remote sensing data, meteorological measurements and ethnographic materials indicate the initial landscape-climatic confinement of settlements and subsequent trans-formations of the steppe landscapes surrounding them were influenced by a complex of natural and anthropo-genic factors. The main factor which influenced the emergence of settlements was the presence of water bodies and, to a lesser extent, forests. In the first decades of the 21th century, an increase in air temperature with a de-crease in precipitation increased the dryness of the territory, thereby reducing the duration of the existence of temporary reservoirs until they completely dry out. Anthropogenic factors that influenced the reduction in the number and duration of the existence of temporary lakes include the widespread plowing of steppe landscapes, as a result of which they lost the ability to retain melt and rainwater for a long time. Currently, in connection with the water supply, the importance of confined settlements to temporary lakes began to decline, but aridization leads to the loss of resource, aesthetic and recreational functions of landscapes.
To the periodisation of the Transitional Period from the Bronze Epoch to Early Iron Age in the lower Ishim River basin
Authors: Zakh V.A.
Published: September 2024

In the end of the 1st millennium BCE, in the lower Ishim River basin, the events were taking place that turned out to be groundbreaking in the history of Western Siberia. As in the bordering southern-taiga and forest-steppe territories of the Tobol and Irtysh river basins, under the changing environmental conditions and increasing migra-tion flow from the taiga regions, there begins the development of cultures precursive to the establishment of the cultural formations of the Early Iron Age. The representatives of the tradition of crossed ornamentation of ware, penetrating into the forest-steppe, commingled with the indigenous Late Bronze Age pastoralist population. The developed, as a result, complexes and cultures of Ust’-Utyak, Krasnoozerka, Late Irmen, and Zavyalovo, according to the materials, represent the stages within the timeframe of the Transitional Period, which, in our opinion, con-tinued until the formation of established Sargatka and Bolsherechenskaya Cultures. In the lover Ishim basin, tran-sition from the Bronze to Iron Age, as it would seem, spans the period from the formation of the Krasnoozersk Culture (the Ishim basin variant), including the stages of its development — Efimovo, Borki, Marai, and Li-khachevo,— until the emergence of Sargatka complexes. In the population of the Lower Lower Ishim basin and bordering territories, taiga traditions retain — building of fortified settlements with above-ground dwellings was in common practice, burials were performed in earthen graves or there was another type of interment. There ap-pears to be a rapid change of the material culture. It would seem that from the 4th c. BCE a reorientation towards the tradition of the forest-steppe and steppe cultures was taking place. There appear ground-deepened dwellings and a ceremony of burial under kurgan mounds. Similar processes with various nuances can be observed virtu-ally across the entire forest-steppe and southern-steppe belt of Western Siberia.
Correlation of endometrial tumor DNA mismatch repair status and MELF-pattern invasion
Authors: DiNobile Charissa , Kertowidjojo Elizabeth , Burke William M. , Gossner Gabrielle , Tornos Carmen , Pearl Michael L.
Published: September 2024

Introduction: Endometrial adenocarcinoma is the most common gynecologic malignancy in the United States. Between 10% and 30% of endometrial adenocarcinomas exhibit microsatellite instability (MSI), a genetic hypermutability that results from an impaired DNA mismatch repair (MMR). MSI can be indirectly identified by immunohistochemical (IHC) staining for deficient MMR protein expression and may be associated with adverse clinical outcomes. The microcystic, elongated, and fragmented (MELF) pattern of invasion can be identified on histologic review and has also been associated with adverse clinical outcomes. It is unknown whether this phenotype of invasion is associated with MSI, and to date, no studies have correlated MMR status and MELF-pattern invasion in endometrial adenocarcinoma. In this study, we examine the correlation between these factors. Methods: We performed an IRB-approved, retrospective review of medical records and pathology slides of surgical cases of endometrioid endometrial adenocarcinoma between January 2016 and January 2020. Results: MMR mutations were present in 35%, MELF-pattern invasion was present in 29%, and both factors were present in 9.4% of specimens. We did not demonstrate a correlation between MMR mutation status and the presence of MELF-pattern invasion (p = 0.15). Conclusions: Our study did not demonstrate a relationship between MMR status and the presence of MELF-pattern invasion. MSI instability may not play a role in the pathogenesis of MELF-pattern invasion. Future study into the association between MELF-pattern invasion and other genetic mutations that arise within endometrial adenocarcinoma is warranted.
Screen use and mental health: the need to strengthen the information ecosystem
Authors: Broilo Patricia Liebesny , Fortes Amanda Borges , Lisboa Carolina S.M.
Published: September 2024

Despite the long-claimed harm associated with the intensive use of screen-based technologies, the measures to curb the COVID-19 pandemic in early 2020 promoted increased screen time. We investigated this behavior at two junctures: during lockdowns and post-lockdowns. Our overarching goal was to deepen the understanding of how intensive screen use correlates with negative and positive mental health outcomes, considering different purposes and circumstances of use. Furthermore, building on infodemic research, we explored the use of trusted sources of information and information sharing, alongside certainty of knowledge and context-related distress. We aimed to determine whether perceived trustworthy sources help individuals cope with uncertainty, notwithstanding possible misinformation. An online survey conducted in June 2020 (T1, n = 327) and repeated in June 2021 (T2, n = 300) with Brazilian adults (18+ years) revealed significant correlations: individuals who perceived increased screen time showed higher anxiety, and those who reported greater information sharing showed higher distress; using screens for novel activities correlated with higher well-being; and despite the awareness of the spread of unreliable content, seeking information ranked as the top purpose for using screens. Surprisingly, individuals who relied on official health channels revealed lower certainty and more distress than those who prioritized other sources. Our findings emphasize the importance of understanding the diverse purposes and circumstances for using screens and the significant role of trusted information sources in coping with uncertainty. Moreover, this study underscores the urgent need for an approach to health communications that can effectively help build a healthy information ecosystem.
Gallbladder Burkitt’s Lymphoma: A Literature Review Including a Case Report in a Child Living with HIV
Authors: Duarte Nathalia Lopez , Bueno Ana Paula Silva , Sanches Bárbara Sarni , Ramos Gabriella Alves , Batista Layanara Albino , Abreu Thalita Fernandes de , Land Marcelo Gerardin Poirot , Milito Cristiane Bedran
Published: September 2024

Malignant lymphoma is an unusual form of gallbladder neoplasm. Almost all of these tumors are diffuse large B-cell lymphomas or mucosa-associated lymphoid tissue-type lymphomas. Herein, we report a rare case of a gallbladder Burkitt’s lymphoma (BL) in a child living with HIV. As far as we are concerned, this is the secondfirst report in the pediatric population and the first one in an individual living with HIV. The patient (a five-year-old black female child) attended the Federal Hospital of Lagoa, Rio de Janeiro, Brazil, underwent cholecystectomy and the postoperative pathological analysis of the gallbladder revealed a diagnosis of BL (EBV-positive). Also, HIV serology was performed and returned positive. She was transferred to the Martagão Gesteira Institute of Pediatrics and Childcare for oncological treatment, dying from sepsis and disease progression about 18 months later. Patient did not undergo ART/cART. Previous cases of gallbladder BL were herein described and analyzed to characterize the clinicopathological features and possible similarities. BL can occur in the gallbladder both in the context of HIV infection and in the pediatric population. Biopsy is mandatory in cases with suggestive findings of lymphoma, and an early diagnosis can change the course of the disease. Furthermore, the case highlights the importance of an early initiation of ART/cART in people living with HIV (PLWH).
Machine Learning Discoveries of NFκB-X Synergy in ETC-1922159 Treated Colorectal Cancer Cells
Authors: Sinha Shriprakash
Published: September 2024

Often, in biology, we are faced with the problem of exploring relevant unknown biological hypotheses in the form of myriads of combinations of factors/genes/proteins that might be affecting the pathway under certain conditions. In colorectal cancer (CRC) cells treated with ETC-1922159, many genes were found up and down regulated, individually. A recently developed search engine ranked combinations of Nuclear factor kappa-light-chain-enhancer of activated B cells (NFκB)-X (X, a particular gene/protein) at 2nd order level after drug administration. These rankings reveal which NFκB-X combinations might be working synergistically in CRC. If found true, oncologists can further test the combination of interest in wet lab and determine the mechanism of functioning between the NFκB and X. In this research work, we cover combinations of caspase (CASP) with receptor interacting serine/threonine kinase (RIPK) family, mucin (MUC) family with RIPK, tumor necrosis factor (TNF) with NF-κB family and NF-κB-Inhibitor (NF-κB-I), NFκB-2/I with STAT family, IκB kinase ε (IKBKE) with STAT family, IKBKE with conjugal transfer protein (TRAF), ATP-binding cassette (ABC) domain transporters with NFκB, IKBKE with ubiquitination modifier enzyme and ubiquitination conjugating enzymes (UBA/UBE) and REL-A/B with NFκB .
Sanitary Decision of Pig Carcasses affected by Osteomyelitis at the Slaughterhouse: from Etiopathogenesis to Total Condemnation Criteria
Authors: Rodrigues¹ Melissa Alves , Teiga-Teixeira Pedro , Seixas Fernanda , Esteves Alexandra
Published: September 2024

Osteomyelitis is a significant cause of total carcass condemnation in pigs at the slaughterhouse. The decision for total condemnation of a pig carcass for osteomyelitis is often based on traditional perceptions of the risk of pyemia, leading to controversy among Official Veterinarians (OV) in the industry. This review aims to provide a more comprehensive understanding of the etiopatho-genesis of osteomyelitis in pigs, the microorganisms involved, and the risk factors. It also high-lights the urgent need for a more uniform method to evaluate osteomyelitis cases, which could significantly reduce economic losses in the industry. Lesions originating from tail-biting, tail docking, castration, teeth resection, and raw management are described as risk factors for oste-omyelitis. Osteomyelitis is caused by the entry of pathogens into the bloodstream of the animal through an open wound. The most described pathogens are Trueperella monocytogenes, Staphylo-coccus aureus, and Streptococcus spp. At slaughter, OVs condemn carcasses with osteomyelitis due to pyemia. Signs of acute disease are essential to identify pyemia cases. In chronic cases, total carcass condemnation can be avoided depending on the number of lesions and number of vertebrae af-fected. A clear overall image of the problem would help authorities in various countries adopt a more homogenous approach.
Rethinking Freshwater Cage Aquaculture: The Case of Ghana
Authors: Banini Philip Kwasi , Anyan Kofi Ferni , Zornu Jacob , Ackah Mabel , Batsa David Narteh , Issifu Kwasi , Amankwah Abigail , Ali Shimaa E. , Addo Samuel , Cudjoe Kofitsyo S.
Published: September 2024

Lakes across the globe, including the Volta Lake in Ghana, face insidious threats from pollutants driven by high dependency on aquatic ecosystems. Cage aquaculture is expanding in Africa due to its potential to address food insecurity, provide livelihoods, and contribute to local economies. However, the uncontrolled expansion of cage aquaculture can have significant negative impacts on water resources, including environmental footprints that threaten biodiversity. Considering the intensification of cage aquaculture on the Volta Lake, we argue for a shift to sustainable alternative aquaculture systems. Deepening stakeholder collaborations are needed to enhance competence in mapping inland aquaculture areas, identifying eco-friendly alternatives, and strengthening aquaculture regulations and their enforcement in general and cage culture in particular on Lake Volta. This approach would promote best management practices. While competence building must be a continuous process to address knowledge gaps, the establishment of workable preparedness plans is needed in the event of emergencies. As the Lake is a hotspot for certain fish pathogens, implementing these strategies can reduce disease risks and subsequently decrease the development of resistance associated with excessive antimicrobial use in farmed fish.
Transcatheter Embolization of Systemic-to-Pulmonary Collaterals – A New Approach Using Concerto™ Helix Nylon-fibered Microcoils
Authors: Pfeifer Jochen , Poryo Martin , Gheibeh Anas , Rentzsch Axel , Abdul-Khaliq Hashim
Published: September 2024

Background: Systemic-to pulmonary collaterals (SPC) are common in congenital heart disease (CHD). Particularly in single ventricle anatomy and Fontan circulation, SPC can both complicate the postoperative course and lead to clinical deterioration in the long term. Treatment of SPC is controversial. The aim of our study was (1) to analyze retrospectively patients who underwent SPC embolization using Concerto™ Helix nylon-fibred microcoils (CHM) and (2) to describe the interventional technique. Methods: In this a single-center retrospective observational cohort study, we analyzed clinical and imaging data of all patients who underwent transcatheter embolization of SPC using CHM from January 2016 to December 2023. Results: In 38 consecutive patients (65.8 % male, median age 41 months, range 2 – 490), a total number of 141 CHM had been implanted into 64 SPC in 49 procedures. The majority were arterial SPC (n = 59/64) originating from the thoracic aorta or its branches; 5/64 were veno-venous SPC. Primary closure succeeded in all procedures. The CHM diameters ranged from 3 to 8 mm, with 5 mm being the most commonly used diameter. The mean coil / SPC ratio was 2.6 (range 1.3 – 5.3). CHM implantation was performed via 4 French sheaths. Both detachment and stable positioning was simple and safe. Neither non-target embolization nor coil migration occurred. One complication occurred with a minor vascular injury without clinical relevance. Conclusion: CHM are easy to use and appropriate for SPC embolization in all age groups, including infants, with a low complication rate. The coils are particularly suitable for closure of collaterals with small diameter or tortuous course.
Barley Seed Germination and Seedling Growth Responses to PEG-Induced Drought Stress
Authors: Davidson-Willis Matthew , Wen Guoqi , Samanfar Bahram , Khanal Raja
Published: September 2024

Drought negatively affects the growth and development of barley. To explore the genetic variation in barley under drought stress, ten breeding genotypes were tested using polyethylene glycol-6000 to simulate drought conditions. We observed that drought stress adversely affected germination-related traits across all barley genotypes and this impact varied between genotypes, suggesting genotype-specific drought tolerance. The drought tolerance index was an ideal criterion for selecting drought-tolerant genotypes as it well characterized the gradient responses of barely genotypes to drought stress. Based on this indicator, genotype OB1878-ON-50 is recommended as a significant germplasm resource for breeding programs under lower precipitation conditions due to its superior tolerance to drought stress.
The Golgotha Unveiled from the Writings of Maria Valtorta Is Not the Traditional One
Authors: Matricciani Emilio
Published: September 2024

Maria Valtorta (MV) (1897–1961) – an Italian mystic who claimed to have visions of Jesus’s life – describes Jesus’ crucifixion with many details from which significant data can be retrieved. My investigation based on these data and the topography of northwest Jerusalem in the I century AD, shows that Jesus’ crucifixion place, Golgotha (the “skull”), is neither at the Holy Sepulchre nor in the Garden Tomb area. The paved road to Golgotha she accurately describes arrives at its top with the minimum mean route gradient; its half way defines two distinct tracts with same height and same walking time but different mean route gradient; at half way Jesus is allowed to walk to the top in a spiral country road less steep than the second tract. The paved road leads to a place where few years after Jesus’ crucifixion the Psephinus Tower, described by Flavius Josephus, was erected, in the area known today as the Russian Compound. In conclusion, the Golgotha reveiled by MV’s writings was located at the same site of the Psephinus Tower.