bluuebunny/crossref_metadata_2025 huggingface dataset:
The development of forest fire monitoring and warning system for agroforestry areas in Uttaradit Province, Thailand
Authors: Homhuan S , Humhong C
Published: July 2020

Forest fire occurs regularly in the northern agroforestry of Thailand started in February to April and it causes economic and environmental losses. This study aimed to develop an automatic spatial data analysis system for monitoring and warning and a system for tracking and warning forest fires in agroforestry areas. Near real-time NDVI in dry season was analyzed to estimate the amount of biomass using a relationship between the NDVI and surveyed dataset. The biomass, hotspot, DEM, slope, aspect and relative humidity data were analyzed by Multi-criteria analysis (MCA) for forest fire risk area. The results are presented on web and mobile platform for forest fire warning. The estimated biomass of March was 7.5 to 9.1 tons/hectare, which corresponded with the results obtained from the field survey. The fire risk factors analysis including hotspot density, relative humidity, and landscape were used to produce the five risk levels. Each risk level area from one to five was 11.84 km2, 25.68 km2, 42.28 km2, 30.85 km2 and 20.65 km2, respectively. The forest fire monitoring and warning systems were designed and developed in open-source platform, which can be utilized for forest, fire monitor and warning for local administration as well as farmers in the area.
Hydrogeochemical model of Ciseeng geothermal field, Bogor, West Java
Authors: Ponka M A , Sahdaranr D N , Kurniadi D T , Yoga D A , Sihombing F M H , Supriyanto
Published: July 2020

Ciseeng geothermal field is located Northwest of West Java 40 km from Jakarta. Three surface manifestations are in Tirta Sayaga, Panjang Mountain, and Peyek Mountain. This study aims to build a hydrogeochemical model based on water analysis. The secondary regional geological data are retrieved to complete geological information of Ciseeng. The research method is divided into several stages: introduction includes the literature study, data collection includes the measurement of temperature and pH in several surface manifestations, rock sampling and structural geology analysis in Ciseeng. The type of manifestation that can be found in Ciseeng is a warm pool with chloride fluid type. Extensive travertine deposits were found in all three locations. The fluid temperature of three surface manifestations is about 30-38 °C with pH 6. According to the measurement of Na-K-Ca geothermometer, the reservoir temperature in Ciseeng geothermal field is 180 °C. The three manifestations of Ciseeng geothermal field are classified as mature water based on a ternary plot diagram. The isotopic analysis shows shifting in O18 indicating hydrothermal process due to magmatic activities in the subsurface. It is predicted that Ciseeng geothermal field is part of Salak/Pangrango Mountain geothermal system. The presence of surface manifestation confirms that geological structure trending from North to South, play a significant role to circulate the heated fluid in the subsurface and subsequently to the surface. The result is a geothermal conceptual model of Ciseeng field that shows the fluid origin and movement in the subsurface.
SEM-EDX study on authigenic clay minerals in sandstone of Jatiluhur formation
Authors: Astuti T R P , Aditiyo R , Oktavioni A , Supriyanto
Published: July 2020

The presence of authigenic clay minerals is usually found in sandstones where these minerals grow in the environment itself. Authigenic clay minerals provide benefits to sandstones, especially to determine the quality of porosity and permeability in sandstones. The samples in this study were collected from an outcrop of measured section at Cipamingkis’ River. The main goal of this study was to understand the presence of authigenic clay minerals in sandstones caused by the diagenetic process using Scanning Electron Microscope and Energy Dispersive X-Ray (SEM – EDX method. The results of this study were kaolinite, smectite, and illite found in very dominant amounts in sandstones as pore linings, pore fillings, replacement, and vug fillings.
Identification of accretionary wedge at Sumatra subduction zone using 2D seismic reflection
Authors: Risqi A N , Riyanto A , Hananto N D
Published: July 2020

This research is focusing on structure at Nias Islands subduction zone. Subduction zone Sumatra is the collision zone of Eurasia continental plate and Indo-Australia oceanic plate. Prior to the establishment of the subduction zone there is an event of the making of continental crust in which in this research area is marked by Wharton Fossil Ridge. An odd feature of the Sunda subduction zone is the non-volcanic forearc ridge that comes up raised sea level assemble a lot of islands betwixt the trench and the mainland. The forearc ridge is the cap of a chunky sequence of sediments and sections of sea floor, known as the accretionary wedge, that are folded, faulted and plastered into the upper plate. Accretionary wedge structure which has the melange rock characteristics because of the plates’ subduction, The accretionary wedge could be intrepred using seismic reflection data with characteristic reflector doesn’t formed or visible. The islands offshore southwestern Sumatra might have a akin origin. The most appropriate study of these is Nias, which its southwest coastline is 90 km form the subduction deformation front and 20 km above the dipping plate interface. Southwest of Nias, the oceanic seafloor is dipping at a homogeneous angle 6° to 7° against Nias for a horizontal distance of 25 km beneath the accretionary wedge, where it attaints a depth of just over 10 km. In this research it has been done 2D seismic reflection data processing and the interpretation of the Wharton fossil ridge establishment, subduction zone, and accretionary wedge.
Study on geochemistry of sea water intrusion effect in Jailolo geothermal system
Authors: Fortuna D A , Daud Y , Abidin Z
Published: July 2020

The possibility of seawater intrusion in geothermal systems is very likely to occur. This is caused by several locations of geothermal systems which are very close to the coast. This paper presents a geochemical analysis of the data manifestations of water and gas, to determine the effect of sea water on the Jailolo geothermal system. From the results of the water analysis, it is clear that the effect of sea water intrusion on the Jailolo geothermal system is shown in the anions and cations diagrams, which is almost all of the plots very close to the seawater points. So that the next analysis is focused on the position of mixing sea water with reservoir water and correction of the parameters that are affected by the mixing of sea water. It is intended that the resulting geochemical model can describe the actual reservoir conditions. If we did not include the correction factor to the calculation this will lead into mislead assessment of the reservoir temperature of geochemistry model which is the final result of the study/assessment. It is also necessary take into account for the next step of the process which is exploitation phase.
Characteristics of chromitite mineralization in Sebuku Island based on thin section, polished section, and geochemical data
Authors: Imani S N , Sihombing F M H , Indra T L , Nugraheni R D
Published: July 2020

Sebuku Island is located in Kotabaru Regency, South Kalimantan and is known as one of the main sources of laterite iron in Indonesia. Based on its tectonic setting, Sebuku Island is located within the suture zone that connects Southwest Borneo Block (SWB) and East Java West Sulawesi Block (EJWB). Due to its tectonic setting, Sebuku Island is composed of various rocks associated with suture zone, such as ophiolite rocks. The ophiolite rocks could host mineralization that occurred in Sebuku Island. The aim of this study is to determine the characteristics of lithology and mineralization as determinants of geological processes that influence the formation of rocks and mineral deposits in Sebuku Island. This study was carried out through petrological, petrographic, ore microscopy analysis, and geochemical analysis (x-ray fluorescence). 22 rock samples from Sebuku Island were collected and the result of this research shows that the chromite host rocks are composed of serpentinized dunite and serpentinite. Chromite minerals (FeCr2O4) were found in massive forms with cataclastic, brecciated texture and disseminated with pull-apart texture. Based on observation of the polished sections, it is known that the associated mineral of chromite is magnetite which is an alteration of chromite minerals. Chromitite chemical data shows the chromite composition is Al-rich (Cr# = 0.6) and classified as podiform chromitite formed by fractional crystallization. There are two magma series of igneous rock in the study area i.e. tholeiitic series consists of ultramafic-mafic rocks and calc-alkaline consists of micro-diorite. The abundance of Al2O3 and TiO2 in chromitite shows that Al-rich chromitite has formed in Supra Subduction Zone (SSZ) and has occurred near or above the Moho-transition zone.
Landslide susceptibility map of Bogor Area using analytical hierarchy process
Authors: Wicaksono Y S , Sihombing F M H , Indra T L
Published: July 2020

Landslide is one of the most common disaster in Bogor City and Bogor Regency. BNPB stated that between 2013–2018 there are 44 landslides with death toll of 68 persons. Therefore, it is important to generate map to identify landslide susceptibility in research area. In this study, we try to create landslide susceptibility map of Bogor area (Bogor Regency and Bogor City) using Analytical Hierarchy Process (AHP). We use various factors to identify landslide susceptibility, including slope curvature, slope gradient, topographic wetness index, slope aspect, elevation, stream power index, distance to river, river density, distance to lineament, lineament density, lithology type, soil type, normalized differential vegetation index, rain intensity, land cover, distance to road, and building density. Various factors above are derivative from openly accessed data of Digital Elevation Model (DEM), landslide distribution, Bakosurtanal Map, Landsat 8 Imagery, engineering geology map, rain intensity data, and soil type map. After all, input data collected, the landslide susceptibility map is created using the AHP method. To validate the result, Receiver Operating Characteristic (ROC) applied, the value of the area under the curve (AUC) to determine the success rate of the AHP method is 0.834, this value represents that the landslide suscepbility map produced by the AHP method is a good model.
Reservoir quality derived from routine core analysis data of deep-water turbidite outcrop analogue
Authors: Prasetio R B , Prasojo O A , Oktavioni A
Published: July 2020

Turbidity current is a process where the fluid flows occurs as a turbulent flow where the molecules inside the fluid are moving randomly but with a net movement toward the orientation of the transport. The physical properties of turbidite deposit is highly impacted by the grain size distribution and rock texture during the deposition. The field in this study was an outcrop of Jatiluhur Formation which deposited by turbidity current on deep marine environment. The main goal of this study was to understand the correlation between the petro-physical properties of turbidite deposit with its depositional mechanism using the routine core analysis method. The samples in this study were collected from an outcrop and the routine core analysis data contains the percentage value of porosity and vertical permeability. The result of this study were the porosity was relatively equal to the permeability and depositional mechanism had a significant role in controlling the porosity and the permeability.
Ichnofossil significance on paleogeographic reconstruction and deep water turbidite reservoir
Authors: Grandis G , Prasojo O A
Published: July 2020

Petro-physical properties are the most important factor that controls the quality of the reservoir. Porosity, permeability, and the grain size are the main parameters to measure the quality of the reservoir. Thin section analysis was used to identify the arrangement of the grains within the rock. The existence of trace fossil can change the condition of the parameters of the reservoir. Bioturbation trace in a rock which made by organism activity, Planolites, changes the quality of reservoir significantly. The porosity value in a bioturbated zone was around 80 % and in the non-bioturbated zone wais 5 %. It increased the permeability too. This was identified from the interconnected pores in the bioturbated section, it has 90 % of quartz mineral with the same grain size relatively in bioturbated section and non-bioturbated section. The existence of Planolites trace implied that the outcrop was deposited in the deep-marine environment.
Estimation of anisotropy parameters VTI (vertical transverse isotropy) using velocity variation with offset (VVO) method, case study: BS oil field
Authors: Simarmata K O E , Suroso T , Supriyanto
Published: July 2020

Implementation of anisotropy value in seismic data processing greatly affect seismic cross section image. In addition to enhanced seismic imagery, anisotropy can be used for identification of hydrocarbons. In this study, the vertical transverse isotropy (VTI) anisotropy parameter estimation by the VVO method has been done. The magnitude of the velocity value of the offset/angle is due to the ever-greater velocity with a large incidence angle being the basis of the VVO method to demonstrate the anisotropy effect. The residual moveout result of the time transfer correction caused by the velocity increase will be used as input data. Validity of the VVO method is tested using a synthetic forward modelling to obtain anisotropy parameters that describe the subsurface conditions of the target area which are then applied to the actual data. The results found that residual values continued to increase due to the anisotropy effect and there after the angle of 30 degrees with the value of ɛ = 0.14 and δ = 0.049.
Optimizing seismic attribute to unlock facies change at Eocene-Oligocene fluvial deltaic sandstones of Pematang formation: Case study the “M” field, Central Sumatera Basin
Authors: Karwin  , Haris A
Published: July 2020

The “M” Field is in the Northern most of the Oil Prolific Central Sumatera Basin at Barumun sub-Basin. The field was originally discovered by drilling M-1 well. This well became the first well proving up the presence of hydrocarbon at Pematang Formation in this region. Pematang Formation is unique because it can serve as reservoir rock as well as source rock. The MX reservoir is part of the Pematang Formation. Based on the last drilling data in which it flows 200 barrels of oil. However, the sand of this reservoir disappeared at the other well, even though the location is not too far. This paper addresses the strategic approaches to interpret facies change using Acoustic Impedance (AI) Inversion. The facies change is detected using AI. It is challenging reservoir since its individual thickness is below seismic resolution. Geologically the MX reservoir was deposited under fluvial deltaic lacustrine environment. The result shows that M-2 is in the delta front facies while the M-1 is in the pro-delta facies. Even though only 1.6 km distance between M-2 and M-1 well cause significant facies change. Result of this study is useful for determining development drilling program in this field.
Extraction of pore networks from thin section: A case study from deep marine turbidite outcrop
Authors: Adikusuma R , Prasojo O A , Oktavioni A
Published: July 2020

A reservoir should have pores that can accommodate fluid. This capability is supported by the petrophysical properties which reservoirs have. The petrophysical properties depends on how the sediments were deposited. This study is focused on the deep marine turbidite outcrop. Turbidity currents are a sedimentation process which makes the sediments carried randomly at high velocity and low viscosity. The petrophysical properties such as porosity and permeability could be determined using computational fluid dynamics (CFD) analysis and routine core analysis. The approaches of this study are to analyze the petrophysical properties using CFD analysis and compare the results with the routine core analysis. The samples of this study were nine thin sections collected from the outcrops, especially in the middle and the edges of the turbidite channel. These samples then processed in the CFD software called COMSOL Multiphysics thus the porosity and permeability of these samples could be determined. The results show that the porosity values of the CFD analysis are relatively similar with the routine core analysis has and the permeability values of the CFD analysis are higher than the routine core analysis has.
The Analysis about Synthesis, Structure and Properties of Willemite Ceramic Pigments Obtained by a Sol–Gel Method
Authors: Dimitrov Ts I , Markovska I G , Ibreva Ts H
Published: July 2020

This work focuses on the syntheses of willemite ceramic pigments doped with cobalt and nickel ions (Co2+, Ni2+). The pigments were prepared by the sol−gel process. The phase formation has been studied by X - ray diffraction analysis. The results showed that phase composition depends on sintering temperature, isothermal retention period as well as type of chromophore ion. The basic phase is obtained at even 900 - 1000°C. Color characteristics of the pigments have been measured using the Lovibond Tintometer RT 100 Color–CIELab color measurement. Better results were obtained at pigments synthesized at 1100°C. High temperature ceramic pigments representing solid solution with stable crystalline phase of Zn2SiO4 were obtained. The best pigments have been added to white faience glaze and sanitary ceramics.
Vibration Response Simulation on a High Risk Building with Laminated Rubber Bearing Base Isolation Subjected to Earthquake Excitation
Authors: Hardian F R , Nirbito W
Published: July 2020

In a high risk building like hospitals, laboratories, or school, the response of the building due to earthquake might be very dangerous. To reduce victims and damages in infrastructure, a type of base isolation is installed to the foundation of the building. The base isolation, in form of a laminated rubber bearing, produces a horizontal movement of the structure when subjected to earthquake forces in order to keep the people and equipment safe. Some calculations of the response vibration parameters are observed to determine the optimal characteristics of the base isolation. The Keq Value is 415,120,000 N/m and the total mass of the building is 739,534,249.7 kg as well as the highest vibration force is 4,015,079,348.47 N. The aim of this research is to simulate the lateral motion of the building with base isolation, due to earthquake forces and decide whether the response is as expected of the design.
Storage Allocation For Stocked and Buffer Baskets
Authors: Walitsarangkul Arunrat , Kittithreerapronchai Oran
Published: July 2020

The recent changes in the retailer landscape and the continuous labor shortage in Thailand and have caused many distribution centers to embrace material handling equipment capable of automatically storage and transporting products. This article presents the case study of a home improvement retailer that adopts a vertical lift module (VLM) system into one of its distribution centers. As automatic equipment dedicated for baskets, a VLM system transports two types of baskets, particularly available stock baskets preparing for picking and consolidated baskets waiting for shipping. A preliminary analysis of current operations reveals that the number of baskets allocated for each type is not suitable, resulting in low utilization of the equipment and storage space. After studying the historical data as well as nature of the business, we proposed a simulation to experiment with the effects of the following operating policies (1) the suitable number of baskets allocated for each type (2) storage policy of consolidated baskets and (3) retrieving patterns of consolidated baskets. The results suggest that the suitable level of each factor that reduces the space utilization of 6.67% and vehicles travel time of 37.5%. Nevertheless, travel times of incoming and outgoing lifters are close to similar represented by their utilization.
Simultaneously improved dielectric, optical and conductivity properties of SrLa1−xNdxLiTeO6 double perovskites
Authors: Halizan M Z M , Mohamed Z , Yahya A K
Published: July 2020

In this study, SrLa1-xNdxLiTeO6 (x = 0.00, 0.25, 0.50, 0.75, 1.00) compounds were prepared using the solid-state method, and their structural, optical, dielectric and conductivity properties were investigated. The Rietveld refinement of x-ray diffraction (XRD) data shows that the compound crystallizes in monoclinic symmetry (i.e. P2

1

/n space group). The morphological scanning electron microscopy study reports a larger grain size when the dopant is added. The optical ultraviolet-visible light spectroscopy (UV-Vis) study reveals that the energy band gap decreases as the doping increases from x = 0.00 to 0.50. Dielectric studies using electrochemical impedance spectroscopy (EIS) characterization reveal the non-Debye trend of dielectric real permittivity (ε′) with the enhancement of ε′ at 1 MHz from x = 0.00 to 0.50. ε′ and the dielectric tangent losses (Tan δ) show increment and decrement patterns, respectively, when the temperature is increased. The frequency-dependent conductivity (σ

AC
) plot follows the universal power law at all temperatures, and the σ

AC
behavior in SrLa1-xNdxLiTeO6 is due to the tunneling of polarons.
A variational model for conformation of graphene wrinkles formed on a shrinking solid metal substrate
Authors: Cox Barry , Dyer Tom , Thamwattana Ngamta
Published: July 2020

Chemical vapor deposition is a popular technique for producing high-quality graphene sheets on a substrate. However, the cooling process causes the graphene sheet to experience a strain-induced, out-of-plane buckling. These wrinkles structures can have undesirable effects on the properties of the graphene sheet. We construct a pair of models to analyse the conformation structure of these wrinkles. An arch-shaped wrinkle is first modelled then expanded to incorporate self-adhesion between the wrinkle edges. Variational techniques are employed on both models to determine the optimal conformation for graphene supported on Cu and Ni substrates. We find these models predict a similar structure to experimental analysis of graphene wrinkles on these solid metal substrates.
Semisimple characters for inner forms II: Quaternionic forms of 𝑝-adic classical groups (𝑝 odd)
Authors: Skodlerack Daniel
Published: July 2020

In this article we consider the setGGof rational points of a quaternionic form of a symplectic or an orthogonal group defined over a non-Archimedean local field of odd residue characteristic. We construct all full self-dual semisimple characters forGGand we classify their intertwining classes using endo-parameters. We compute the set of intertwiners between self-dual semisimple characters, and prove an intertwining and conjugacy theorem. Finally we count allGG-intertwining classes of full self-dual semisimple characters which lift to the sameG~\tilde {G}-intertwining class of a full semisimple character for the ambient general linear groupG~\tilde {G}forGG.
Representation of integers by sparse binary forms
Authors: Akhtari Shabnam , Bengoechea Paloma
Published: July 2020

We will give new upper bounds for the number of solutions to the inequalities of the shape

|

F
(
x
,
y
)

|

≤
h

|F(x,y)| \leq h

, where

F
(
x
,
y
)

F(x,y)

is a sparse binary form, with integer coefficients, and

h
h

is a sufficiently small integer in terms of the discriminant of the binary form

F
F

. Our bounds depend on the number of non-vanishing coefficients of

F
(
x
,
y
)

F(x,y)

. When

F
F

is “really sparse”, we establish a sharp upper bound for the number of solutions that is linear in terms of the number of non-vanishing coefficients. This work will provide affirmative answers to a number of conjectures posed by Mueller and Schmidt in [Trans. Amer. Math. Soc. 303 (1987), pp. 241–255], [Acta Math. 160 (1988), pp. 207–247], in special but important cases.
An improved bound in Wirsing’s problem
Authors: Badziahin Dmitry , Schleischitz Johannes
Published: July 2020

We improve the lower bound for the classical exponent of approximation

w

n

∗

w_{n}^{\ast }

connected to Wirsing’s famous problem on approximation to real numbers by algebraic numbers of degree at most

n
n

. Our bound exceeds

n

/

3

≈
0.5773
n

n/\sqrt {3}\approx 0.5773n

and thus provides a considerable qualitative improvement to previous bounds of order

n

/

2
+
O
(
1
)

n/2+O(1)

. We further establish new relations between several classical exponents of approximation.
XMAP215 and γ-tubulin additively promote microtubule nucleation in purified solutions
Authors: King Brianna R. , Moritz Michelle , Kim Haein , Agard David A. , Asbury Charles L. , Davis Trisha N.
Published: July 2020

XMAP215 promotes microtubule nucleation independently as a polymerase of nucleation intermediates. Across a range of polymerase activities, XMAP215 and γ-tubulin function additively, indicating independent modes of action. Any synergistic behavior must arise from unique interactions made in the context of the γ-TuRC.
Practical method for superresolution imaging of primary cilia and centrioles by expansion microscopy using an amplibody for fluorescence signal amplification
Authors: Katoh Yohei , Chiba Shuhei , Nakayama Kazuhisa
Published: July 2020

Expansion microscopy was applied to the observation of primary cilia and centrioles. To compensate for the decrease in fluorescence signal per unit volume inherent in physical expansion, a fluorescence signal amplification tool, called the amplibody, was developed. The method enables the practical observation of cilia and centrioles with high brightness and resolution.
Adjustment Costs and Factor Demand: New Evidence from Firms’ Real Estate
Authors: Bergeaud Antonin , Ray Simon
Published: July 2020

We study corporate real estate frictions and their effect on firm dynamics and labour demand. We build and simulate a general equilibrium model with heterogeneous firms that predicts the response of firms to a productivity shock in the presence of fixed adjustment costs on real estate. Using a large firm-level database merged with local real estate prices, we then exploit variations in the tax on capital gains to document a causal effect of adjustment costs on firms’ labour demand and derive new results on the causes and implications of firms’ local relocation.
Understanding IV antimicrobial drug losses: the importance of flushing infusion administration sets
Authors: Bolla Balwinder , Buxani Yeshmita , Wong Rebecca , Jones Leslie , Dube Michelle
Published: July 2020

Background

IV drugs are commonly prescribed for inpatient treatment. Where administered as infusions, drug dose loss is incurred if the infusion line is not flushed. Underdosing of IV antimicrobials is of particular concern as reduced treatment efficacy increases the risk of patient deterioration (including sepsis) and development of antimicrobial resistance.

Objectives

To quantify drug loss, raise awareness and provide recommendations to address this patient safety risk effectively.

Methods

Percentage drug loss of 39 IV antimicrobials was calculated for a theoretical patient case scenario, using residual volumes for IV infusion lines utilized within this acute healthcare setting. An adult male patient (70 kg) with good renal function was assumed for drug dosing. Infusion volumes and doses are based on a widely used IV administration guide.

Results

Data revealed the scope and extent of antimicrobial drug losses where infusion lines were not flushed as ranging from 2% to 33%. More than 10% of the drug would be lost for 26 of the 39 antimicrobials assessed, with five of these yielding over 20% loss.

Conclusions

The authors suggest that unintentional antimicrobial underdosing is going unnoticed in clinical practice. Where IV infusion is necessary, flushing of the infusion line to ensure total dose administration is strongly recommended. Risks associated with flushing lines (fluid overloading, bolus dosing, etc.) can be managed with simple measures. The authors call for a national body-led approach to effectively influence healthcare organizations in review of IV administration protocols, ensuring patient safety and care in the NHS.
Role of Chrysomya albiceps (Diptera: Calliphoridae) and Musca domestica (Diptera: Muscidae) Maggot Crop Contents in Identifying Unknown Cadavers
Authors: Mohammad Zainab , Alajmi Reem , Alkuriji Mohammed , Metwally Dina , Kaakeh Walid , Almeaiweed Nasser
Published: July 2020

Forensic entomology focuses on the analysis of insect larvae present at crime scenes to help identify unknown cadavers. Carrion-feeding maggots store food in a crop located at the anterior end of the gut. DNA recovered from the crop can be amplified, sequenced, and identified to determine the origin of the food. This information could help investigators to identify a missing victim if maggots are discovered at a crime scene in the absence of a corpse. Chrysomya albiceps (Wiedemann) and Musca domestica (Linnaeus) are primary forensic species. Little or no information on the identification of unknown cadavers using C. albiceps and M. domestica larvae is available, and we aimed to compare the effectiveness of using the crop contents of instars of C. albiceps and M. domestica larvae to identify corpses at different time intervals. Two hundred and forty larvae of both species were reared on rat and/or mouse liver, and DNA from crop contents was extracted after different time intervals from different instar larvae. DNA was amplified using specific primers that match the mitochondrial cytochrome oxidase subunit I (mt COI) gene of the food source. Results showed that food provided to larvae affected life span and the ability to be used to identify unknown cadavers. Chrysomya albiceps larvae proved more useful than M. domestica larvae. Moreover, crop contents of third instar larvae of both species fed for 24 h are more useful than contents from other time intervals in identifying unknown tissues. Results are promising and may help investigators to identify unknown/missing victims.
Comparison of visualization tools for single-cell RNAseq data
Authors: Cakir Batuhan , Prete Martin , Huang Ni , van Dongen Stijn , Pir Pinar , Kiselev Vladimir Yu
Published: July 2020

In the last decade, single cell RNAseq (scRNAseq) datasets have grown in size from a single cell to millions of cells. Due to its high dimensionality, it is not always feasible to visualize scRNAseq data and share it in a scientific report or an article publication format. Recently, many interactive analysis and visualization tools have been developed to address this issue and facilitate knowledge transfer in the scientific community. In this study, we review several of the currently available scRNAseq visualization tools and benchmark the subset that allows to visualize the data on the web and share it with others. We consider the memory and time required to prepare datasets for sharing as the number of cells increases, and additionally review the user experience and features available in the web interface. To address the problem of format compatibility we have also developed a user-friendly R package, sceasy, which allows users to convert their own scRNAseq datasets into a specific data format for visualization.
Stakeholder engagement in research on quality of life and palliative care for brain tumors: a qualitative analysis of #BTSM and #HPM tweet chats
Authors: Salmi Liz , Lum Hillary D , Hayden Adam , Reblin Maija , Otis-Green Shirley , Venechuk Grace , Morris Megan A , Griff Megan , Kwan Bethany M
Published: July 2020

Background

Research is needed to inform palliative care models that address the full spectrum of quality of life (QoL) needs for brain tumor patients and care partners. Stakeholder engagement in research can inform research priorities; engagement via social media can complement stakeholder panels. The purpose of this paper is to describe the use of Twitter to complement in-person stakeholder engagement, and report emergent themes from qualitative analysis of tweet chats on QoL needs and palliative care opportunities for brain tumor patients.

Methods

The Brain Cancer Quality of Life Collaborative engaged brain tumor (#BTSM) and palliative medicine (#HPM) stakeholder communities via Twitter using tweet chats. The #BTSM chat focused on defining and communicating about QoL among brain tumor patients. The #HPM chat discussed communication about palliative care for those facing neurological conditions. Qualitative content analysis was used to identify tweet chat themes.

Results

Analysis showed QoL for brain tumor patients and care partners includes psychosocial, physical, and cognitive concerns. Distressing concerns included behavioral changes, grief over loss of identity, changes in relationships, depression, and anxiety. Patients appreciated when providers discussed QoL early in treatment, and emphasized the need for care partner support. Communication about QoL and palliative care rely on relationships to meet evolving patient needs.

Conclusions

In addition to providing neurological and symptom management, specialized palliative care for brain tumor patients may address unmet patient and care partner psychosocial and informational needs. Stakeholder engagement using Twitter proved useful for informing research priorities and understanding stakeholder perspectives on QoL and palliative care.
Development of a Standardized Data Collection Tool for Evaluation and Management of Coronavirus Disease 2019
Authors: Morris Stephen R , Natori Yoichiro , Salguero Douglas , Mantero Alejandro , Ma Ruixuan , de Lima Corvino Daniela F , Fernandez Anmary , Lazo Alex , Vu Christine A , Bjork Lauren , Serota David , Quevedo Jennifer , Vega Ana , Maxam Meshell , DeRonde Kailynn , Barreiro Pablo , Raccamarich Patricia , Alvarez Maria Romero , Skiada Dimitra , Balan Shuba , Ramanathan Maya , Holt Gregory , Gonzales-Zamora Jose , Baracco Gio J , Doblecki-Lewis Susanne , Abbo Lilian M , Lichtenberger Paola N , Alcaide Maria L
Published: July 2020

Background

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 ) is responsible for coronavirus disease 2019 (COVID-19), a disease that had not been previously described and for which clinicians need to rapidly adapt their daily practice. The novelty of SARS-CoV-2 produced significant gaps in harmonization of definitions, data collection, and outcome reporting to identify patients who would benefit from potential interventions.

Methods

We describe a multicenter collaboration to develop a comprehensive data collection tool for the evaluation and management of COVID-19 in hospitalized patients. The proposed tool was developed by a multidisciplinary working group of infectious disease physicians, intensivists, and infectious diseases/antimicrobial stewardship pharmacists. The working group regularly reviewed literature to select important patient characteristics, diagnostics, and outcomes for inclusion. The data collection tool consisted of spreadsheets developed to collect data from the electronic medical record and track the clinical course after treatments.

Results

Data collection focused on demographics and exposure epidemiology, prior medical history and medications, signs and symptoms, diagnostic test results, interventions, clinical outcomes, and complications. During the pilot validation phase, there was <10% missing data for most domains and components. Team members noted improved efficiency and decision making by using the tool during interdisciplinary rounds.

Conclusions

We present the development of a COVID-19 data collection tool and propose its use to effectively assemble harmonized data of hospitalized individuals with COVID-19. This tool can be used by clinicians, researchers, and quality improvement healthcare teams. It has the potential to facilitate interdisciplinary rounds, provide comparisons across different hospitalized populations, and adapt to emerging challenges posed by the pandemic.
Non-SUSY Gepner models with vanishing cosmological constant
Authors: Aoyama Koji , Sugawara Yuji
Published: July 2020

In this article we discuss a construction of non-SUSY type II string vacua with the vanishing cosmological constant at the one-loop level based on the generic Gepner models for Calabi–Yau 3-folds. We make an orbifolding of the Gepner models by $\Bbb Z_2 \times \Bbb Z_4$, which asymmetrically acts with some discrete torsions incorporated. We demonstrate that the obtained type II string vacua indeed lead to the vanishing cosmological constant at the one-loop level, whereas any space-time supercharges cannot be constructed as long as we assume chiral forms such as “$ \displaystyle {\cal Q}^{\alpha}_L \equiv \oint dz\, {\cal J}_L^{\alpha}(z) $”. We further discuss possible generalizations of the models described above.
Muscle elasticity in patients with neonatal brachial plexus palsy using shear-wave ultrasound elastography. Preliminary results
Authors: Riquier-Le Chatelier Morgane , Giai Joris , Lallement-Dudek Pauline , Herisson Olivier , Fitoussi Frank
Published: July 2020

Ultrasound shear wave elastography (SWE) is a noninvasive, reliable and reproducible method, used for the qualitative and quantitative evaluation of tissues. The aim of this study was to compare muscle elasticity between the healthy and the involved sides in children with neonatal brachial plexus palsy (NBPP) using the elastography tool and to assess whether the difference was correlated with the Mallet grading system. We repeatedly measured the shear modulus coefficient of several muscles around the shoulder in stretched or passively relaxed positions on 14 patients. We evaluated the abductor muscles (supraspinatus and deltoid), the infraspinatus, the pectoralis major and the latissimus dorsi. We found a mean shear modulus significantly higher in most studied muscles in the pathologic side (P < 0.001), especially in the stretched position (P < 0.001). Moreover, the shear modulus increases with the degradation of the Mallet score for the abduction and external rotation tasks. SWE seems to be a reliable and reproducible tool to assess muscle elasticity in NBPP.
‘In-Out-In’ K-wires sliding in severe tibial deformities of osteogenesis imperfecta: a technical note
Authors: Langlais Tristan , Pannier Stéphanie , De Tienda Marine , Dukan Ruben , Finidori Georges , Glorion Christophe , Péjin Zagorka
Published: July 2020

Severe infant osteogenesis imperfecta requires osteosynthesis. Intramedullary tibia’s osteosynthesis is a technical challenge given the deformity and the medullar canal’s narrowness. We describe an extramedullary technique: ‘In-Out-In’ K-wires sliding. We performed an anteromedial diaphysis approach. The periosteum was released while preserving its posterior vascular attachments. To obtain a straight leg, we did numerous osteotomies as many times as necessary. K-wires (‘In’) were introduced into the proximal epiphysis, and the medial malleolus (‘Out’) bordered the cortical and (‘In’) reach their opposite metaphysis. K-wires were cut, curved and impacted at their respective epiphysis ends to allow a telescopic effect. All tibial fragments are strapped on K-wires, and the periosteum was sutured over it. Our inclusion criteria were children with osteogenesis imperfecta operated before 6 years old whose verticalization was impossible. Seven patients (11 tibias) are included (2006–2016) with a mean surgery’s age of 3.3 ± 1.1 years old. All patients received intravenous bisphosphonates preoperatively. The follow-up was 6.1 ± 2.7 years. All patients could stand up with supports, and the flexion deformity correction was 46.7 ± 14.2°. Osteosynthesis was changed in nine tibias for the arrest of telescoping with flexion deformity recurrence and meantime first session-revision was 3.8 ± 1.7 years. At revision, K-wires overlap had decreased by 55 ± 23%. Including all surgeries, three distal K-wires migrations were observed, and the number of surgical procedures was 2.5/tibia. No growth arrest and other complications reported. ‘In-Out-In’ K-wires sliding can be considered in select cases where the absence of a medullary canal prevents the insertion of intramedullary rod or as a salvage or alternative procedure mode of fixation. It can perform in severe infant osteogenesis imperfecta under 6 years old with few complications and good survival time.
Identifying Risk Areas of Medication Administration Process for Developing an Interactive Three-Dimensional Game Intervention
Authors: Härkänen Marja , Luokkamäki Sanna , Saano Susanna , Saastamoinen Tiia , Vehviläinen-Julkunen Katri
Published: July 2020

The aim of this study was to describe identified risk areas related to the medication administration process in acute care in order to develop a three-dimensional-game intervention. A secondary analysis was conducted using (1) observed medication administrations (n = 1058) and identified medication errors in 2012 (n = 235), (2) a systematic review including a meta-analysis of previous medication administration educational interventions (n = 14) from 2000 to 2015, (3) incident reports of medication administration errors (n = 1012) from 2013 to 2014, and (4) focus group interviews with RNs' (n = 20) views in 2015. A qualitative content analysis was used to identify risk areas, and the data were organized according to the following main themes: (1) factors related to patients (patient identification, patients' characteristics or symptoms, and patients' allergies and interactions); (2) factors related to medications (medication information, changes in medications, generic substitutes, new drugs, look-alike/sound-alike drugs, demanding drug treatments, medication preparation, and administration techniques); (3) factors related to staffing (workload, skills, interruptions and distractions, division of work, responsibility, attitudes, and guidelines); and (4) factors related to communication (flow of information, communication with the patients, and marking of medication information). Identified risk areas could be used to develop interventions with the aim of increasing the safety of medication administration and nurses' skills.
Taxonomic Triangulation of Care in Healthcare Protocols
Authors: González–Aguña Alexandra , Fernández–Batalla Marta , Gasco–González Sara , Cercas–Duque Adriana , Jiménez–Rodríguez María Lourdes , Santamaría–García José María
Published: July 2020

Taxonomic triangulation is a data mining technique for the management of care knowledge. This technique uses standardized languages, such as North American Nursing Diagnosis Association International, Nursing Outcomes Classification, and Nursing Interventions Classification, as well as logic. Its purpose is to find patterns in the data and identify care diagnoses. Triangulation can be applied to databases (clinical records) or to bibliographic sources (eg, protocols). The objective of this study is to identify the care diagnoses implicit in the nursing care protocols of the Community of Madrid. The method followed has three phases: knowledge extraction for mapping of variables, linking to diagnoses, and triangulation with analysis. The study analyzes six protocols, and 344 variables (167 assessment, 29 planning, and 148 intervention) and 6118 links have been extracted. Triangulation identified 165 NANDA diagnoses (68.48%), and only 25 labels were not revealed through this process. As a limitation, the results depend on the knowledge presented in protocols and change with language editions. Some labels included in the sample are recent and are not included in the links with nursing outcomes classification and nursing interventions classification. In conclusion, taxonomic triangulation makes it possible to manage knowledge, discover data patterns, and represent care situations.
Follistatin Like 5 (FSTL5) inhibits epithelial to mesenchymal transition in hepatocellular carcinoma
Authors: Zhang Deng-Yong , Lei Jia-Sheng , Sun Wan-Liang , Wang Dong-Dong , Lu Zheng
Published: July 2020

Background

Epithelial to mesenchymal transition (EMT) is a key process in determining distant metastasis and intra-hepatic dissemination of hepatocellular carcinoma (HCC). Follistatin (FST) family members are considered to be an attractive therapeutic targets and prognostic indicators in cancers. As a derivative of FST, Follistatin Like 5 (FSTL5) may play a similar role in HCC cells. This study aimed to investigate the expression and function of FSTL5 in HCC and its role in EMT.

Methods

FSTL5, E-cadherin and vimentin in HCC, and paracancerous tissues were detected by immunohistochemistry. Correlation of FSTL5 expression with overall survival was assessed. The proliferation and invasion of HCC cell lines SK-Hep1 and MHCC-LM3 were analyzed by cell counting kit-8 and Transwell assays. The expression of FSTL5, E-cadherin, and vimentin in HCC cells was examined by polymerase chain reaction and Western blot analysis. T-test was used to analyze the difference in proliferation and invasion ability between groups. The Spearman rank correlation test was used to detect the correlation between the expression of FSTL5 and E-cadherin or vimentin.

Results

The expression of FSTL5 in HCC was lower than that in paracancerous tissues (9.97% vs. 82.55%, χ
2 = 340.15, P 
< 0.001). Patients with high FSTL5 expression had a better prognosis (χ
2 = 8.22, P = 0.004) and smaller tumor diameter (χ
2 = 45.52, P 
< 0.001), less lymph node metastasis (χ
2 = 5.58, P 
= 0.02), earlier tumor node metastasis stage (χ
2 = 11.29, P = 0.001), a reduced number of tumors (χ
2 = 5.05, P = 0.02), lower alpha-fetoprotein value (χ
2 = 24.36, P 
< 0.001), more probability of hepatitis carrying (χ
2 = 40.9, P 
< 0.001), and better liver function grade (χ
2 = 5.21, P = 0.02). Immunohistochemistry showed that FSTL5 expression in HCC tissues was positively correlated with E-cadherin expression (r = 0.38, P < 0.001) and negatively correlated with vimentin expression (r 
= −0.385, P 
< 0.001). Furthermore, over-expression of FSTL5 up-regulated the expression of E-cadherin and down-regulated the expression of vimentin in SK-Hep1 (negative control [NC] vs. FSTL5-interfering group [Lv-FSTL5]: E-cadherin [t = 45.03, P 
< 0.001], vimentin [t = 67, P 
< 0.001]) and MHCC-LM3 (NC vs. Lv-FSTL5: E-cadherin [t = 50, P 
< 0.001], vimentin [t = 72.75, P 
< 0.001]) cells at mRNA level. The same as protein level. In addition, the over-expression of FSTL5 inhibited the proliferation (NC vs. Lv-FSTL5: SK-Hep1, 3 d [t = 7.324, P = 0.018], 4 d [t = 6.23, P = 0.021], 5 d [t = 10.21, P = 0.003]; MHCC-LM3, 3 d [t = 4.32, P = 0.037], 4 d [t = 7.49, P = 0.012], 5 d [t = 9.3661, P = 0.009]) and invasion (NC vs. Lv-FSTL5: SK-Hep1, t = 21.57, P 
< 0.001; MHCC-LM3, t = 18.04, P 
< 0.001) of HCC cells.

Conclusions

Down-regulation of FSTL5 may contribute to EMT of HCC, and FSTL5 is a potential target in the treatment of HCC.