bluuebunny/crossref_metadata_2025 huggingface dataset:
Relationship between TEC jumps and auroral substorm in the high-latitude ionosphere
Authors: Chernyshov A. A. , Miloch W. J. , Jin Y. , Zakharov V. I.
Published: April 2020

The influence of an auroral substorm on the total electron content (TEC) jumps and cycle slips on Global Positioning System (GPS) at high-latitudes is studied. For the first time, optical data from the all-sky imager, as well as interplanetary magnetic field and magnetometer data are used to complete the analysis of the slips occurrence and to monitor the substorm evolution. Two types of slips are considered: (i) instrumental slips including losses in the measured phase of the GPS signal and (ii) sharp TEC variations (TEC jumps) It is demonstrated that the jumps in TEC determined from the GPS signals are mainly related to the auroral particle precipitation that normally occurs during geomagnetic substorms in the polar ionosphere. The GPS frequency $${L}_{2}$$L2 is consistently subject to more slips than frequency $${L}_{1}$$L1 both for quiet and disturbed conditions. The probability of TEC jumps is higher than for cycle slips in phase at frequencies $${L}_{1}$$L1 and $${L}_{2}$$L2. The maximum of TEC jumps is observed during the recovery phase of the auroral substorm. Our findings are based on a data set obtained for a particular event. A generalization of the obtained numerical estimates to other events requires additional research and further analysis.
Melatonin modulates red-ox state and decreases viability of rat pancreatic stellate cells
Authors: Gonzalez Antonio , Estaras Matias , Martinez-Morcillo Salome , Martinez Remigio , García Alfredo , Estévez Mario , Santofimia-Castaño Patricia , Tapia Jose A. , Moreno Noelia , Pérez-López Marcos , Míguez María P. , Blanco-Fernández Gerardo , Lopez-Guerra Diego , Fernandez-Bermejo Miguel , Mateos Jose M. , Vara Daniel , Roncero Vicente , Salido Gines M.
Published: April 2020

In this work we have studied the effects of pharmacological concentrations of melatonin (1 µM–1 mM) on pancreatic stellate cells (PSC). Cell viability was analyzed by AlamarBlue test. Production of reactive oxygen species (ROS) was monitored following CM-H2DCFDA and MitoSOX Red-derived fluorescence. Total protein carbonyls and lipid peroxidation were analyzed by HPLC and spectrophotometric methods respectively. Mitochondrial membrane potential (ψm) was monitored by TMRM-derived fluorescence. Reduced (GSH) and oxidized (GSSG) levels of glutathione were determined by fluorescence techniques. Quantitative reverse transcription-polymerase chain reaction was employed to detect the expression of Nrf2-regulated antioxidant enzymes. Determination of SOD activity and total antioxidant capacity (TAC) were carried out by colorimetric methods, whereas expression of SOD was analyzed by Western blotting and RT-qPCR. The results show that melatonin decreased PSC viability in a concentration-dependent manner. Melatonin evoked a concentration-dependent increase in ROS production in the mitochondria and in the cytosol. Oxidation of proteins was detected in the presence of melatonin, whereas lipids oxidation was not observed. Depolarization of ψm was noted with 1 mM melatonin. A decrease in the GSH/GSSG ratio was observed, that depended on the concentration of melatonin used. A concentration-dependent increase in the expression of the antioxidant enzymes catalytic subunit of glutamate-cysteine ligase, catalase, NAD(P)H-quinone oxidoreductase 1 and heme oxygenase-1 was detected in cells incubated with melatonin. Finally, decreases in the expression and in the activity of superoxide dismutase were observed. We conclude that pharmacological concentrations melatonin modify the redox state of PSC, which might decrease cellular viability.
High expression of oxidative phosphorylation genes predicts improved survival in squamous cell carcinomas of the head and neck and lung
Authors: Frederick Mitchell , Skinner Heath D. , Kazi Sawad A. , Sikora Andrew G. , Sandulache Vlad C.
Published: April 2020

Mitochondrial activity is a critical component of tumor metabolism, with profound implications for tumorigenesis and treatment response. We analyzed clinical, genomic and expression data from patients with oral cavity squamous cell carcinoma (OCSCC) in order to map metabologenomic events which may correlate with clinical outcomes and identified nuclear genes involved in oxidative phosphorylation and glycolysis (OXPHOG) as a critical predictor of patient survival. This correlation was validated in a secondary unrelated set of lung squamous cell carcinoma (LUSC) and was shown to be driven largely by over-expression of nuclear encoded components of the mitochondrial electron transport chain (ETC) coordinated with an increase in tumor mitochondrial DNA copy number and a strong threshold effect on patient survival. OCSCC and LUSC patients with a favorable OXPHOG signature demonstrated a dramatic (>2fold) improvement in survival compared to their counterparts. Differential OXPHOG expression correlated with varying tumor immune infiltrates suggesting that the interaction between tumor metabolic activity and tumor associated immunocytes may be a critical driver of improved clinical outcomes in this patient subset. These data provide strong support for studies aimed at mechanistically characterizing the interaction between tumor mitochondrial activity and the tumor immune microenvironment.
Changes in seminal parameters among Brazilian men between 1995 and 2018
Authors: Siqueira Samyra , Ropelle Anne Caroline , Nascimento Josiane A. A. , Fazano Francisco A. T. , Bahamondes Luis Guillermo , Gabiatti José Roberto , Costa-Paiva Lúcia , Baccaro Luiz Francisco
Published: April 2020

Aiming to investigate trends in seminal parameter values among Brazilian men between 1995 and 2018, we performed a retrospective analysis of spermograms of couples admitted for infertility testing at UNICAMP/Brazil. For the present study, only the first sample produced by each man was analyzed (9,267 samples). Total motile sperm count (TMSC), percentage of spermatozoa with normal morphology (NM), and sperm concentration after seminal processing (SCA) were considered dependent variables. Statistical analysis was carried out through linear regression for the median values both in the general population and in the population categorized by age group (<30, 30–39, and ≥40 years). During the study period, the mean age of men was 32.46 (± 6.48) years, with a median of 32 (18–67) years. We found a significant decrease in the median values of TMSC (reduction of 2.84 million/year), NM (reduction of 0.52% each year) and SCA (reduction of 0.24 million/mL each year). In conclusion, we observed that Brazilian men undergoing infertility investigation had a decline in seminal parameters in the past 23 years. Surveillance should be maintained in the coming years, and further studies are needed to elucidate possible causes for seminal deterioration and to devise strategies to reverse this trend.
Success rate of proximal tooth-coloured direct restorations in primary teeth at 24 months: a meta-analysis
Authors: Ortiz-Ruiz Antonio J. , Pérez-Guzmán Nuria , Rubio-Aparicio María , Sánchez-Meca Julio
Published: April 2020

The aim was to determine the survival of tooth-coloured restorative materials in proximal restorations of primary teeth at 24 months of follow-up and the influence of the following variables: use of coating, use of cavity conditioner, use of rubber dam isolation, the cavity form, the dentist’s experience and the methodological characteristics of the studies. We conducted a search until May 2019, obtaining 16 articles from which 30 independent studies were extracted, which were considered as units of analysis. Four outcome measures were extracted from each study: retention, marginal integrity, anatomic form, and absence of recurrent caries. Separate meta-analyses were carried for each outcome and multiple meta-regression model was applied. The outcomes with the highest mean success rates were absence of recurrent caries and anatomic form. The type of material significantly influenced success rates. The best materials were resin-based material plus total-etching adhesion and resin-modified glass ionomer cement (RMGIC), and the worst high viscosity glass ionomer cement (HVGIC). Atraumatic restorative treatment (ART) had a lower success rate than the conventional cavity form. RMGIC had the best clinical performance and HVGIC the worst. The form of the cavity, blinding and the experience of the operator were the variables that influenced success rates. Proximal primary molar restorations should be performed with RMGIC as it combines good mechanical performance of the resins together with the prevention of secondary caries of glass ionomers.
Transgene integration causes RARB downregulation in homozygous Tg4–42 mice
Authors: Hinteregger Barbara , Loeffler Tina , Flunkert Stefanie , Neddens Joerg , Birner-Gruenberger Ruth , Bayer Thomas A. , Madl Tobias , Hutter-Paier Birgit
Published: April 2020

Alzheimer’s disease can be modelled by different transgenic mouse strains. To gain deeper insight into disease model mechanisms, the previously described Tg4–42 mouse was analysed for transgene integration. On RNA/DNA level the transgene integration resulted in more than 20 copy numbers and further caused a deletion of exon 2 of the retinoic acid receptor beta. These findings were also confirmed on protein level with highly decreased retinoic acid receptor beta protein levels in homozygous Tg4–42 mice and may have an impact on the previously described phenotype of homozygous Tg4–42 mice to be solely dependent on amyloid-ß 4–42 expression. Since hemizygous mice show no changes in RARB protein levels it can be concluded that the previously described phenotype of these mice should not be affected by the retinoic acid receptor beta gene knockout. In order to fully understand the results of transgenesis, it is extremely advisable to determine the genome integration site and the basic structure of the inserted transgenes. This can be carried out for instance by next-generation sequencing techniques. Our results thus suggest that a detailed characterization of new disease models using the latest genomics technologies prior to functional studies could be a valuable tool to avoid an unexpected genetic influence on the animals’ phenotype that is not only based on the inserted transgene. This would also significantly improve the selection of mouse models that are best suited for therapeutic development and basic research.
Preoperative Serum Fibrinogen is Associated With Acute Kidney Injury after Cardiac Valve Replacement Surgery
Authors: Yang Jing Juan , Lei Wen Hua , Hu Peng , Wu Bin Bin , Chen Jian Xiao , Ni Yi Ming , Lai En Yin , Han Fei , Chen Jiang Hua , Yang Yi
Published: April 2020

Acute kidney injury (AKI) after open cardiac surgery is associated with a longer hospital stay and higher risk of mortality. We aimed to explore the association between preoperative serum fibrinogen level and risk of postoperative AKI in patients with open cardiac surgery. 3459 patients who underwent cardiac valve replacement surgery from January 2011 to September 2015 were recruited. The primary outcome was AKI, defined as AKI stage-1 or higher based on the Kidney Disease: Improving Global Outcomes (KDIGO) Guidelines. Synthetic Minority Oversampling Technique (SMOTE) was used to subsample minority groups to eliminate classification bias. 510 (14.74%) patients developed postoperative AKI. Serum fibrinogen was independently associated with AKI (OR = 1.211, 95% CI 1.080 to 1.358, p = 0.001) after adjustment of covariates. The receiver operator characteristic (ROC) curve for the outcome of AKI, after the addition of serum fibrinogen, had a c-statistic increasing from 0.72 to 0.73 (p < 0.001). This translated to a substantially improved AKI risk classification with a net reclassification index of 0.178 (p < 0.001). After SMOTE subsampling, serum fibrinogen was still independently associated with AKI grade 1 or higher (OR = 1.212, 95% CI 1.1089 to 1.347, p = 0.003). Preoperative serum fibrinogen levels were associated with the risk of postoperative AKI after cardiac valve replacement surgery.
Identification and local manipulation of bone marrow vasculature during intravital imaging
Authors: Morikawa Takayuki , Tamaki Shinpei , Fujita Shinya , Suematsu Makoto , Takubo Keiyo
Published: April 2020

Physiological regulation of blood flow in bone marrow is important to maintain oxygen and glucose supplies but also the physiological hypoxic state of the hematopoietic stem cell (HSC) niche. However, regulatory mechanisms underlying microcirculation in the bone marrow (BM) niche remain unclear. Here, we identify vessels functioning in control of blood flow in bone marrow and assess their contractility. To evaluate contractile potential of Alexa Fluor 633 (AF633; an arterial marker)-positive vessels, we performed immunohistochemistry for α-smooth muscle actin (α-SMA) and found it expressed around AF633+ vessels in the femoral and calvarial marrow. To validate AF633+ vessel contractility, we developed a simple system to locally administer vasoactive agents that penetrate BM through transcalvarial vessels. After exposure of the calvarial surface to FITC-dextran (70 kDa), FITC intensity in calvarial bone marrow gradually increased. When we evaluated the effect of transcalvarial administration (TCA) of norepinephrine (NE) on vascular tone of AF633+ arteries and behavior of transplanted blood cells, NE administration decreased artery diameter and transendothelial migration of transplanted cells, suggesting that adrenergic signaling regulates the HSC niche microcirculation and blood cell migration into the BM via effects on BMarteries. We conclude that TCA is a useful tool for bone marrow research.
Determining nitrogen isotopes discrimination under drought stress on enzymatic activities, nitrogen isotope abundance and water contents of Kentucky bluegrass
Authors: Saud Shah , Fahad Shah , Cui Guowen , Yajun Chen , Anwar Sumera
Published: April 2020

Drought stress is the most pervasive threat to plant growth, which predominantly encumbers turf grass growth by causing alterations in plant functions. This study appraised the role of nitrogen isotopes in providing a theoretical basis for developing and improving Kentucky bluegrass cultivar performance under drought stress. Nitrogen isotopes labelled 15NH4Cl and K15NO3 were prepared to replace KNO3 in Hoagland’s solution at concentrations of 15NH4+ and 15NO3 at 1.5, 15, and 30 mM; the solutions were imposed on stressed plants under glasshouse conditions. Nitrogenous nutrition reduced oxidative stress by elevating the enzymatic activities and proline contents of all three clonal ramet leaves, particularly under stress conditions. Apart from nitrogen content, nitrogen isotope abundance, relative water content and water potential within controls were enhanced in treated with 15NH4+ than in with 15NO3 in both the roots and leaves of Kentucky bluegrass. Nevertheless, an application of 15NH4Cl and K15NO3 at 30 mM had a positive influence to some extent on these attributes under drought stress. Overall, our results suggested that nitrogen isotopes contributed to drought tolerance in all three clonal ramets of Kentucky bluegrass by maintaining a better osmoprotectant and antioxidant defence system, which helped the plants eliminate reactive oxygen species.
Effect of Cellulose Nanocrystals Extracted from Oil Palm Empty Fruit Bunch as Green Admixture for Mortar
Authors: Mazlan Dianah , Krishnan Santhana , Din Mohd Fadhil Md , Tokoro Chiharu , Khalid Nur Hafizah Abd , Ibrahim Izni Syahrizal , Takahashi Hideki , Komori Daisuke
Published: April 2020

This paper aims to examine the effect of cellulose nanocrystals (CNCs) derived from oil palm empty fruit bunch fiber (EFB) incorporating cement mortar on its structural performances. Cellulose nanocrystals (CNCs) were extracted from α-cellulose extracted from EFB using an acid hydrolysis process with a concentration of acid used was 64% w/v under the temperature of 45 °C for 60 minutes. The Cellulose nanocrystals (CNCs) were mixed into the cement mortar ranging from 0 to 0.8% w/w and its mechanical properties were determined. The developed CNCs mortar was characterized for their compressive and flexural properties as well as microstructure. The influence of CNCs concentration, curing method, dispersion of CNCs on mortar’s mechanical performance was thoroughly examined to find out the optimum condition. Overall results revealed that an addition of 0.4% cellulose nanocrystals has shown to increase the compressive and flexural strength to 46% and 20%, respectively cured under the wrapping method. The hydration of cementitious composites also improved significantly with the addition of CNCs by the formation of highly crystalline of portlandite observed under the XRD test. This present work demonstrates the importance of palm oil empty fruit bunch waste as a sustainable resource of cellulose nanocrystals admixture to achieve structural strength of cement mortar and promotes green technologies in construction.
Protected Health Information filter (Philter): accurately and securely de-identifying free-text clinical notes
Authors: Norgeot Beau , Muenzen Kathleen , Peterson Thomas A. , Fan Xuancheng , Glicksberg Benjamin S. , Schenk Gundolf , Rutenberg Eugenia , Oskotsky Boris , Sirota Marina , Yazdany Jinoos , Schmajuk Gabriela , Ludwig Dana , Goldstein Theodore , Butte Atul J.
Published: April 2020

There is a great and growing need to ascertain what exactly is the state of a patient, in terms of disease progression, actual care practices, pathology, adverse events, and much more, beyond the paucity of data available in structured medical record data. Ascertaining these harder-to-reach data elements is now critical for the accurate phenotyping of complex traits, detection of adverse outcomes, efficacy of off-label drug use, and longitudinal patient surveillance. Clinical notes often contain the most detailed and relevant digital information about individual patients, the nuances of their diseases, the treatment strategies selected by physicians, and the resulting outcomes. However, notes remain largely unused for research because they contain Protected Health Information (PHI), which is synonymous with individually identifying data. Previous clinical note de-identification approaches have been rigid and still too inaccurate to see any substantial real-world use, primarily because they have been trained with too small medical text corpora. To build a new de-identification tool, we created the largest manually annotated clinical note corpus for PHI and develop a customizable open-source de-identification software called Philter (“Protected Health Information filter”). Here we describe the design and evaluation of Philter, and show how it offers substantial real-world improvements over prior methods.
Heterogeneous nitrogen fixation rates confer energetic advantage and expanded ecological niche of unicellular diazotroph populations
Authors: Masuda Takako , Inomura Keisuke , Takahata Naoto , Shiozaki Takuhei , Sano Yuji , Deutsch Curtis , Prášil Ondřej , Furuya Ken
Published: April 2020

Nitrogen fixing plankton provide nitrogen to fuel marine ecosystems and biogeochemical cycles but the factors that constrain their growth and habitat remain poorly understood. Here we investigate the importance of metabolic specialization in unicellular diazotroph populations, using laboratory experiments and model simulations. In clonal cultures of Crocosphaera watsonii and Cyanothece sp. spiked with 15N2, cellular 15N enrichment developed a bimodal distribution within colonies, indicating that N2 fixation was confined to a subpopulation. In a model of population metabolism, heterogeneous nitrogen (N2) fixation rates substantially reduce the respiration rate required to protect nitrogenase from O2. The energy savings from metabolic specialization is highest at slow growth rates, allowing populations to survive in deeper waters where light is low but nutrients are high. Our results suggest that heterogeneous N2 fixation in colonies of unicellular diazotrophs confers an energetic advantage that expands the ecological niche and may have facilitated the evolution of multicellular diazotrophs.
Exhaled breath condensate based breath analyser – a disposable hydrogen peroxide sensor and smart analyser
Authors: Chen Yu-Chih , O'Hare Danny
Published: April 2020

A smart breath analyser with ultra-sensitive disposable hydrogen peroxide sensor for exhaled breath condensate based lung inflammation diagnostics.
Polydopamine-assisted one-step modification of nanofiber surfaces with adenosine to tune the osteogenic differentiation of mesenchymal stem cells and the maturation of osteoclasts
Authors: Ahmad Taufiq , Byun Hayeon , Shin Hyeok Jun , Lee Jinkyu , Madhurakkat Perikamana Sajeesh Kumar , Kim Eun Mi , Shin Young Min , Shin Heungsoo
Published: April 2020

Adenosine and its receptors have emerged as alternative targets to control cellular functions for bone healing.
Arbitrarily-shaped microgels composed of chemically unmodified biopolymers
Authors: Vakkipurath Kodakkadan Yadu N. , Idzakovicova Kristyna , Sepitka Josef , ten Napel Daniël , Safai Eric , Cigler Petr , Štěpánek Frantisek , Rehor Ivan
Published: April 2020

We introduce a method for photolithographic synthesis of arbitrarily shaped microgels composed purely of a biopolymer of choice.
Device physics of back-contact perovskite solar cells
Authors: Yang Zhenhai , Yang Weichuang , Yang Xi , Greer J. C. , Sheng Jiang , Yan Baojie , Ye Jichun
Published: April 2020

A fundamental theory including photoelectric response, ion migration and photon recycling effects for back-contact perovskite solar cells is established.
Development and characterisation of acoustofluidic devices using detachable electrodes made from PCB
Authors: Mikhaylov Roman , Wu Fangda , Wang Hanlin , Clayton Aled , Sun Chao , Xie Zhihua , Liang Dongfang , Dong Yinhua , Yuan Fan , Moschou Despina , Wu Zhenlin , Shen Ming Hong , Yang Jian , Fu Yongqing , Yang Zhiyong , Burton Christian , Errington Rachel J. , Wiltshire Marie , Yang Xin
Published: April 2020

We demonstrate a novel SAW device fabrication technique by mechanically clamping interdigital electrodes (IDEs) on the printed circuit board (PCB) to a LiNbO3 wafer. The novel PCB-SAW device is capable of performing all the functions of standard SAW devices.
Molecular docking-assisted design and synthesis of an anti-tumor quercetin–Se(iv) complex
Authors: Chen Xu , Wu Xianyong , He Ziyu , Zhang Juan , Cao Ya , Mao Dongsheng , Feng Chang , Tian Bo , Chen Guifang
Published: April 2020

Design and synthesis of an anti-tumor quercetin–Se(iv) complex under the guidance of molecular docking and visualized DNA binding activity.
In vitro prebiotic activities of oligosaccharides from the by-products in Ganoderma lucidum spore polysaccharide extraction
Authors: Yang Kai , Zhang Yajie , Cai Ming , Guan Rongfa , Neng Jing , Pi Xionge , Sun Peilong
Published: April 2020

Until recently, a variety of oligosaccharides from fruits, vegetables and mushrooms have demonstrated positive prebiotic effects.
High salt compatible oxyanion receptors by dual ion imprinting
Authors: Shinde Sudhirkumar , Mansour Mona , Incel Anil , Mavliutova Liliia , Wierzbicka Celina , Sellergren Börje
Published: April 2020

Imprinting of an ion-pair in presence of mutually compatible anion and cation host monomers leads to polymers showing enhanced ion uptake in competitive high ionic strength buffers.
Selective ratiometric red-emission detection of In3+ in aqueous solutions and in live cells using a fluorescent peptidyl probe and metal chelating agent
Authors: Park Joohee , Yu Hyeongseok , Park See-Hyoung , Lee Keun-Hyeung
Published: April 2020

A ratiometric fluorescent detection method for In3+ in aqueous buffered solution, ground water, and live cells was developed.
A polypyrrole-coated eightfold-helical Wells–Dawson POM-based Cu-FKZ framework for enhanced colorimetric sensing
Authors: Li Qian , Xu Mingqi , Li Xiao , Li Shuxian , Hou Liran , Chen Yuhao , Sha Jingquan
Published: April 2020

A new Wells–Dawson-type CuFKZP2W18-based hybrid compound containing eightfold helical chains is reported, and its CuFKZP2W18/PPy(15%) composite exhibits excellent peroxidase-like catalytic activity.
Room-temperature doping of ytterbium into efficient near-infrared emission CsPbBr1.5Cl1.5 perovskite quantum dots
Authors: Zhao Shuangyi , Zhang Yubo , Zang Zhigang
Published: April 2020

Doping of Yb can facilitate the enhancement of NIR quantum yield in CsPbBr1.5Cl1.5 perovskite quantum dots.
Co-Inclusion of cyclic ethers and chloroform by a macrocycle with benzophenone-3,3′,4,4′-tetracarboxylic diimide units
Authors: Tominaga Masahide , Mizuno Kosuke , Yamamoto Haruka , Hyodo Tadashi , Yamaguchi Kentaro
Published: April 2020

Crystallization of a diimide-based macrocycle having adamantane parts and several cyclic ethers in chloroform provided inclusion crystals, where both guests were cooperatively accommodated within inner spaces between the macrocycles.
Chemical potentials of electric double layers at metal–electrolyte interfaces: dependence on electrolyte concentration and electrode materials, and application to field-effect transistors
Authors: Nanjo Chihiro , Yokogawa Daisuke , Matsushita Michio M. , Awaga Kunio
Published: April 2020

We experimentally and theoretically reveal the chemical potentials of electric double layers at metal–electrolyte interfaces for carrier injections.
A comprehensive study of the thermal conductivity of the hard sphere fluid and solid by molecular dynamics simulation
Authors: Pieprzyk Sławomir , Brańka Arkadiusz C. , Heyes David M. , Bannerman Marcus N.
Published: April 2020

Comprehensive molecular dynamics calculations of the thermal conductivity of the hard sphere fluid and solid were performed.
Nanoporous carbon for electrochemical capacitive energy storage
Authors: Shao Hui , Wu Yih-Chyng , Lin Zifeng , Taberna Pierre-Louis , Simon Patrice
Published: April 2020

This review summarizes the recent advances of nanoporous carbon materials in the application of EDLCs, including a better understanding of the charge storage mechanisms by combining the advanced techniques and simulations methods.
Carbon nanotube/PTFE as a hybrid platform for lipase B from Candida antarctica in transformation of α-angelica lactone into alkyl levulinates
Authors: Szelwicka Anna , Kolanowska Anna , Latos Piotr , Jurczyk Sebastian , Boncel Slawomir , Chrobok Anna
Published: April 2020

A highly active biocatalyst based on a hybrid platform was designed for the conversion of α-angelica lactone to alkyl levulinates.
Ultralow loading of nanostructured Mn species onto two-dimensional Co3O4 nanosheets for selective catalytic reduction of NOx with NH3
Authors: Zheng Kang , Zhou Zhiyuan , Wang Yongzhao , Xin Zhiling , Zhao Zhiliang , Zhang Jing , Bo Tingting , Lin Tsungwu , Zhang Bingsen , Shao Lidong
Published: April 2020

We report a facile method for dispersing Mn species onto two-dimensional Co3O4 nanosheets at the nanoscale for the selective catalytic reduction (SCR) of NOx with NH3.
ESI MS studies highlight the selective interaction of Auranofin with protein free thiols
Authors: Zoppi Carlotta , Messori Luigi , Pratesi Alessandro
Published: April 2020

The study of the mode-of-action of Auranofin, a cytotoxic gold(i) compound, reveals that it binds exclusively to the free and solvent-accessible cysteine residues of biologically relevant proteins.
Luminescent organic dyes containing a phenanthro[9,10-D]imidazole core and [Ir(N^C)(N^N)]+ complexes based on the cyclometalating and diimine ligands of this type
Authors: Solomatina Anastasia I. , Kuznetsov Kirill M. , Gurzhiy Vladislav V. , Pavlovskiy Vladimir V. , Porsev Vitaly V. , Evarestov Robert A. , Tunik Sergey P.
Published: April 2020

New N^N and N^C luminescent ligands with solvatochromic behavior and their iridium complexes were synthesized, characterized and investigated.
Development of functionality of metal complexes based on proton-coupled electron transfer
Authors: Kojima Takahiko
Published: April 2020

Proton-coupled electron transfer (PCET) is ubiquitous and fundamental in many kinds of redox reactions. In this paper, are described PCET reactions in metal complexes to highlight their useful and unique properties and functionalities.
High-temperature, high-pressure hydrothermal synthesis, crystal structure, and infrared and NMR spectroscopy of a barium lead borate with a 2D layer structure: [Ba3Pb(H2O)][B11O19(OH)3]
Authors: Kuo Yu-Chen , Liu Hsin-Kuan , Wang Sue-Lein , Lii Kwang-Hwa
Published: April 2020

The structure of the hydrothermally synthesized barium lead borate contains an unusual fundamental building block, 2Δ4□:〈Δ2□〉–〈3□〉Δ, which was also found in the high-pressure form of CaB2O4synthesized at 900 °C under a pressure of 15–25 kbar.
Sorption of sulfamethoxazole on biochars of varying mineral content
Authors: Li Jing , Chen Yihui , He Liping , Liang Ni , Wang Lin , Zhao Jing , Pan Bo
Published: April 2020

Negative charge assisted H-bond played a significant role in sulfamethoxazole sorption for low-temperature biochars (200–300 °C), while Ca-containing mineral content facilitated SMX sorption as pyrolysis temperature increased.
Visible-light-promoted oxidative desulphurisation: a strategy for the preparation of unsymmetrical ureas from isothiocyanates and amines using molecular oxygen
Authors: Gan Ziyu , Li Guoqing , Yan Qiuli , Deng Weiseng , Jiang Yuan-Ye , Yang Daoshan
Published: April 2020

A green and efficient visible-light promoted oxidative desulphurisation protocol has been proposed for the construction of unsymmetrical ureas under mild conditions with broad substrate scope and good functional group tolerance.
Transition-state rate theory sheds light on ‘black-box’ biodegradation algorithms
Authors: Nolte T. M. , Peijnenburg W. J. G. M. , van Bergen T. J. H. M. , Hendriks A. J.
Published: April 2020

An algebraic formula stemming from transition-state rate theory using simple electronic, geometrical and energetic properties can improve our understanding of biodegradation via ‘first principles’.
Continuous hydroformylation of 1-decene in an aqueous biphasic system enabled by methylated cyclodextrins
Authors: Künnemann K. U. , Schurm L. , Lange D. , Seidensticker T. , Tilloy S. , Monflier E. , Vogt D. , Dreimann J. M.
Published: April 2020

Long-term applications of cyclodextrins in the aqueous biphasic hydroformylation of higher olefins with high selectivities and simultaneous catalyst recycling.
Transport mechanism of copper sulfide embedded carbon nitride thin films: a formation free memristor
Authors: Perla Venkata K. , Ghosh Sarit K. , Mallick Kaushik
Published: April 2020

Nonvolatile electrical resistive behaviour was demonstrated for a copper sulfide nanoparticle decorated carbon nitride (CSCN) based device.
Glucose-responsive cascaded nanocatalytic reactor with self-modulation of the tumor microenvironment for enhanced chemo-catalytic therapy
Authors: Mei Linqiang , Ma Dongqing , Gao Qin , Zhang Xiao , Fu Wenhui , Dong Xinghua , Xing Gengmei , Yin Wenyan , Gu Zhanjun , Zhao Yuliang
Published: April 2020

Here, a glucose-responsive cascaded nanocatalytic reactor was proposed for enhanced synergetic chemo-catalytic therapy through persistent TME self-modulation.
Bio-inspired transparent MXene electrodes for flexible UV photodetectors
Authors: Chen Jiaxin , Li Ziliang , Ni Fenglou , Ouyang Weixin , Fang Xiaosheng
Published: April 2020

A leaf-inspired transparent MXene electrode for UV photodetectors with outstanding flexibility breaks the tradeoff between high transmittance and high conductivity.
Amido rare-earth(iii) and Ca(ii) complexes coordinated by tridentate amidinate ligands: synthesis, structure, and catalytic activity in the ring-opening polymerization of rac-lactide and ε-caprolactone
Authors: Rad’kova Natalia Yu. , Kovylina Tatyana A. , Shavyrin Andrei S. , Cherkasov Anton V. , Fukin Georgy K. , Lyssenko Konstantin A. , Trifonov Alexander A.
Published: April 2020

Y(iii), Sm(iii) and Ca(ii) monoamido complexes coordinated by tridentate amidinate ligand were synthesized and evaluated as initiators of ring-opening polymerization of rac-lactide and ε-caprolactone.
Iron doping boosts the reactivity and stability of the γ-Al2O3 nanosheet supported cobalt catalyst for propane dehydrogenation
Authors: Zhang Chang-Wu , Wen Jing , Wang Lei , Wang Xin-Ge , Shi Lei
Published: April 2020

This study describes a new iron-doping strategy to improve both the reactivity and stability of a cobalt catalyst in propane dehydrogenation, meanwhile, the defective γ-Al2O3 nanosheet synergistically boosted the dehydrogenating activity of that.
Enhanced carrier transport by transition metal doping in WS2 field effect transistors
Authors: Liu Maomao , Wei Sichen , Shahi Simran , Jaiswal Hemendra Nath , Paletti Paolo , Fathipour Sara , Remškar Maja , Jiao Jun , Hwang Wansik , Yao Fei , Li Huamin
Published: April 2020

Both generalized atomic doping and localized contact decoration using transition metal, Cu, can significantly improve the contact condition and enhance the carrier transport of two-dimensional semiconductors.
DFT coupled with NEGF study of the electronic properties and ballistic transport performances of 2D SbSiTe3
Authors: Hu Xuemin , Qu Hengze , Xu Lili , Liu Wenqiang , Guo Tingting , Cai Bo , Yu Xuechao , Zhu Junwu , Zhang Shengli
Published: April 2020

By first-principle calculations, we predicted that monolayer SbSiTe3 possesses a wide band gap with a flat valence band maximum. The p-type field effect transistors can effectively suppress the short channel effect at sub-10 nm.
Enhanced magnetic properties and thermal stability of highly ordered ε-Fe3N1+x (−0.12 ≤ x ≤ −0.01) nanoparticles
Authors: Li Yong , Pan Desheng , Zhou Yangtao , Kuang Qifeng , Wang Chinwei , Li Bing , Zhang Bingsen , Park Jihoon , Li Da , Choi Chuljin , Zhang Zhidong
Published: April 2020

Carbon-coated ε-Fe3N1+x (x < 0) nanoparticles with highly ordered nitrogen occupancy show higher magnetic properties and thermal stability than previously reported bulk materials.
Miniemulsion polymerization of styrene using carboxylated graphene quantum dots as surfactant
Authors: Dinh Le N. M. , Ramana Lakshmi N. , Agarwal Vipul , Zetterlund Per B.
Published: April 2020

Carboxylated graphene quantum dots (cGQDs) were synthesized from dextrose and sulfuric acid via a hydrothermal process, and subsequently used as sole surfactant in miniemulsion polymerization of styrene.
Cooperative photoredox and chiral hydrogen-bonding catalysis
Authors: Yin Yanli , Zhao Xiaowei , Qiao Baokun , Jiang Zhiyong
Published: April 2020

Chiral hydrogen-bonding catalysis is a classic strategy in asymmetric organocatalysis. Recently, it has been used to cooperate with photoredox catalysis, becoming a powerful tool to access optical pure compounds via radical-based transformations.
Poly(ethylene glycol)–poly(propylene glycol)–poly(ethylene glycol) and polyvinylidene fluoride blend doped with oxydianiline-based thiourea derivatives as a novel and modest gel electrolyte system for dye-sensitized solar cell applications
Authors: Karthika P. , Ganesan S.
Published: April 2020

A unique gel polymer electrolyte was prepared using PVDF and PEG–PPG–PEG block copolymer with I−/I3− for DSSC application. This is a cost-effective method used for the synthesis of thiourea additives. The GPE with OPPT thiourea additive achieved a good efficiency of 5.7%.
A comparative study on the evolution of the interface chemistry and electrical performance of ALD-driven HfxTiyAlzO nanolaminates
Authors: Gao Juan , He Gang , Hao Lin , Wang Die , Zhao Lin
Published: April 2020

Ternary HfTiO and TiAlO films and quaternary HfTiAlO films prepared with different stoichiometric ratios via atomic layer deposition were deposited on Si substrates. HfTiAlO possesses more excellent interface performance and electrical properties than HfTiO and TiAlO.
The design and growth of peanut-like CuS/BiVO4 composites for photoelectrochemical sensing
Authors: Yang Yang , Liang Junting , Jin Wenwen , Li Yingyue , Xuan Menghui , Wang Shijie , Sun Xiaoqian , Chen Chuanliang , Zhang Jianhua
Published: April 2020

In this study, the CuS/BiVO4-X (where X represents the mass percentage of CuS associated with CuS/BiVO4; X = 2%, 5% and 7%) p–n heterostructures were fabricated using a two-step hydrothermal method.
Electrochemical proton-coupled electron transfer of an anthracene-based azo dye
Authors: Oldacre Amanda N. , Young Elizabeth R.
Published: April 2020

Herein, we report the thermodynamics, kinetics, and mechanism for electrochemical proton-coupled electron transfer involving the anthracene-based azo dye azo-OMe.
Solventless synthesis of cerium oxide nanoparticles and their application in UV protective clear coatings
Authors: Álvarez-Asencio Rubén , Corkery Robert W. , Ahniyaz Anwar
Published: April 2020

Solventless synthesis of metal oxide nanoparticles.
Investigating the effects of adding hybrid nanoparticles, graphene and boron nitride nanosheets, to octadecane on its thermal properties
Authors: Tafrishi Hossein , Sadeghzadeh Sadegh , Molaei Fatemeh , Siavoshi Hossein
Published: April 2020

Octadecane is an alkane that is used to store thermal energy at ambient temperature as a phase change material.
Atomic and electronic structure of solids of Ge2Br2PN, Ge2I2PN, Sn2Cl2PN, Sn2Br2PN and Sn2I2PN inorganic double helices: a first principles study
Authors: Bijoy T. K. , Murugan P. , Kumar Vijay
Published: April 2020

We report the results of density functional theory calculations on the atomic and electronic structure of solids formed by assembling A2B2PN (A = Ge and Sn, B = Cl, Br, and I) inorganic double helices.
Iodine/water-mediated deprotective oxidation of allylic ethers to access α,β-unsaturated ketones and aldehydes
Authors: Xue Yuntian , Yan Yaolong , Jiang Kezhi , Chen Weifeng , Yang Lei
Published: April 2020

The first iodine/water-mediated deprotective oxidation of allylic ethers to access α,β-unsaturated ketones and aldehydes was effectively achieved.
Correction: Microwave-assisted catalytic conversion of glucose to 5-hydroxymethylfurfural using “three dimensional” graphene oxide hybrid catalysts
Authors: Hirano Yui , Beltramini Jorge N. , Mori Atsushi , Nakamura Manami , Karim Mohammad Razaul , Kim Yang , Nakamura Masaaki , Hayami Shinya
Published: April 2020

Correction for ‘Microwave-assisted catalytic conversion of glucose to 5-hydroxymethylfurfural using “three dimensional” graphene oxide hybrid catalysts’ by Yui Hirano, Shinya Hayami et al., RSC Adv., 2020, 10 , 11727–11736.
Correction: Affinity binding of chicken apolipoprotein A1 to a novel flax orbitide (linusorb)
Authors: Jadhav Pramodkumar D. , Young Shim Youn , Reaney Martin J. T.
Published: April 2020

Correction for ‘Affinity binding of chicken apolipoprotein A1 to a novel flax orbitide (linusorb)’ by Pramodkumar D. Jadhav, et al., RSC Adv., 2018, 8, 17702–17709.
Crystallization at droplet interfaces for the fabrication of geometrically programmed synthetic magnetosomes
Authors: Stoller Michael A. , Gromowsky Matthew , Rauhauser Maddee , Judah Marcus , Konda Abhiteja , Jurich Christopher P. , Morin Stephen A.
Published: April 2020

A strategy applicable to the synthesis of artificial magnetosomes with programmable magnetic domains is described. The magnetic domains are polarized and thus readily manipulated using magnetic fields or assembled using droplet–droplet interactions.
A "trimurti" heterostructured hybrid with an intimate CoO/CoxP interface as a robust bifunctional air electrode for rechargeable Zn–air batteries
Authors: Niu Yue , Xiao Meiling , Zhu Jianbing , Zeng Taotao , Li Jingde , Zhang Wenyao , Su Dong , Yu Aiping , Chen Zhongwei
Published: April 2020

The synergistic effects of triphasic cobalt-based nanoparticles andtheir superior structural features enable unprecedented bifunctional catalytic efficiency and durability.
The critical effect of water content in the electrolyte on the reversible electrochemical performance of Zn–VPO4F cells
Authors: Yaghoobnejad Asl Hooman , Sharma Shyam , Manthiram Arumugam
Published: April 2020

The critical role of water as a source of H+ working ions and reactive species in the Zn–VPO4F electrochemical system with an ionic liquid electrolyte.
Design principles of pseudocapacitive carbon anode materials for ultrafast sodium and potassium-ion batteries
Authors: Gao Yong , Zhang Jing , Li Nan , Han Xiao , Luo Xian , Xie Keyu , Wei Bingqing , Xia Zhenhai
Published: April 2020

Na and K-ion batteries are promising energy storage devices at low cost, but their inferior rate and capacity have hampered application. We develop the design principles to screen pseudocapacitive carbon anode materials to create ultrafast batteries.
In situ conversion of metal (Ni, Co or Fe) foams into metal sulfide (Ni3S2, Co9S8 or FeS) foams with surface grown N-doped carbon nanotube arrays as efficient superaerophobic electrocatalysts for overall water splitting
Authors: Guo Mingrui , Qayum Abdul , Dong Shun , Jiao Xiuling , Chen Dairong , Wang Ting
Published: April 2020

Metal (Ni, Co or Fe) foams can be in situ converted into metal sulfide (Ni3S2, Co9S8 or FeS) foams with surface grown N-doped carbon nanotube arrays, and work as efficient superaerophobic electrocatalysts for overall water splitting.
Electrochemical conversion of bulk platinum into platinum single-atom sites for the hydrogen evolution reaction
Authors: Wang Zhiyuan , Yang Jia , Gan Jie , Chen Wenxing , Zhou Fangyao , Zhou Xiao , Yu Zhenqiang , Zhu Junfa , Duan Xuezhi , Wu Yuen
Published: April 2020

An electro-filtration strategy is used to access a Pt single-atom sites catalyst on graphite carbon paper at room temperature from Pt foil, assisted by a GOM membrane. It exhibits excellent activity and stability towards HER (with CdS) under visible-light irradiation.
Anderson polyoxometalate built-in covalent organic frameworks for enhancing catalytic performances
Authors: Ma Rui , Liu Naifang , Lin Ting-Ting , Zhao Tianbo , Huang Sheng-Li , Yang Guo-Yu
Published: April 2020

Anderson polyoxometalate-based covalent organic frameworks exhibited the highest catalytic activity in the photodegradation of RhB and MB, as well as 100% selective oxidation of sulfides to sulfoxides.
A universal and facile approach to suppress dendrite formation for a Zn and Li metal anode
Authors: Cao Jin , Zhang Dongdong , Zhang Xinyu , Sawangphruk Montree , Qin Jiaqian , Liu Riping
Published: April 2020

A universal and facile approach using a graphene oxide (GO) modified separator is used to suppress dendrite formation in Zn and Li metal anodes, via the preferential growth of non-protruding crystal planes.
MOF-derived Fe,Co@N–C bifunctional oxygen electrocatalysts for Zn–air batteries
Authors: Duan Xinde , Ren Shuangshuang , Pan Na , Zhang Mingdao , Zheng Hegen
Published: April 2020

MOF-derived Fe,Co@N-C bifunctional electrocatalysts for oxygen reduction reactions and oxygen evolution reactions have been prepared via a scalable method, exhibiting ultra-high catalytic activity and promising performance in Zn–air batteries.
Rapidly dissolving microneedle patch for synergistic gene and photothermal therapy of subcutaneous tumor
Authors: Xu Qinan , Li Xinfang , Zhang Peng , Wang Youxiang
Published: April 2020

Synergistic gene and photothermal therapy conducted by p53 DNA/IR820 MN patch may be a promising strategy for subcutaneous tumor treatments.
Polymer-encapsulation of iron oxide clusters using macroRAFT block copolymers as stabilizers: tuning of the particle morphology and surface functionalization
Authors: Guimarães Thiago Rodrigues , Lansalot Muriel , Bourgeat-Lami Elodie
Published: April 2020

We report a versatile platform for the preparation of magnetic carriers stabilized by macroRAFT amphiphilic block copolymers, exhibiting encapsulated morphologies, high iron oxide content and tailored surface functionalizations.
Glutathione- and light-controlled generation of singlet oxygen for triggering drug release in mesoporous silica nanoparticles
Authors: Wong Roy C. H. , Ng Dennis K. P. , Fong Wing-Ping , Lo Pui-Chi
Published: April 2020

An activatable phthalocyanine-based photosensitiser and a singlet-oxygen-triggered doxorubicin releasing system have been incorporated into mesoporous silica nanoparticles, which can release the encapsulated doxorubicin in a controllable manner.
Smart sensing of Cu2+ in living cells by water-soluble and nontoxic Tb3+/Eu3+-induced aggregates of polysaccharides through fluorescence imaging
Authors: Wang Jing , Liu Jin , Wang Jing , Wang Yao , Cao Jie , Hou Lin , Ge Ruifen , Chi Jinnan , Huang Linjun , Guo Junlan , Aleem Abdur Raheem , Song Zhengxing , Tamang Shree Krishna , Liu Jixian , Wang Guanghui , Kipper Matt J. , Belfiore Laurence A. , Tang Jianguo
Published: April 2020

Nano-sized TIPA is illustrated “off–on” detection of Cu2+ in aqueous and 4T1 cells.
Ultralong CH3NH3PbI3 nanowires synthesized by a ligand-assisted reprecipitation strategy for high-performance photodetectors
Authors: He Xu , Jian Chuanyong , Hong Wenting , Cai Qian , Liu Wei
Published: April 2020

Organic–inorganic hybrid perovskite nanowires with well-defined structures have attracted considerable attention for optoelectronic applications.
Cell division cycle proteinising prognostic biomarker of breast cancer
Authors: Cheng Lin , Huang Yu-Zhou , Chen Wei-Xian , Shi Liang , Li Zhi , Zhang Xu , Dai Xin-Yuan , Wei Ji-Fu , Ding Qiang
Published: April 2020

Cell division cycle protein (CDC20) has been observed to be expressed higher in various kinds of human cancers and was associated with poor prognosis. However, studies on role of CDC20 in breast cancer are seldom reported till now, most of which are not systematic and conclusive. The present study was performed to analyze the expression pattern, potential function, and distinct prognostic effect of CDC20 in breast cancer using several online databases including Oncomine, bc-GenExMiner, PrognoScan, and UCSC Xena. To verify the results from databases, we compared the mRNA CDC20 expression in breast cancer tissues and adjacent normal tissues of patients by real-time PCR. We found that CDC20 was expressed higher in different types of breast cancer, comparing with normal tissues. Moreover, the patients with a more advanced stage of breast cancer tended to express higher level CDC20. CDC20 was expressed higher in breast cancer tissues than normal tissues from patients in our hospital, consistent with the results from databases. Estrogen receptor (ER) and progesterone receptor (PR) status were negatively correlated with CDC20 level. Conversely, Scarff–Bloom–Richardson (SBR) grade, Nottingham prognostic index (NPI), epidermal growth factor receptor-2 (HER-2) status, basal-like status, and triple-negative status were positively related to CDC20 expression in breast cancer patients with respect to normal individuals. Higher CDC20 expression correlated with worse survival. Finally, a positive correlation between CDC20 and Targeting protein for Xenopus kinesin-like protein 2 (TPX2) expression was revealed. CDC20 could be considered as a potential predictive indicator for prognosis of breast cancer with co-expressed TPX2 gene.
MiR-139-5p influences hepatocellular carcinoma cell invasion and proliferation capacities via decreasing SLITRK4 expression
Authors: Wu Jisiguleng , Zhang Tong , Chen Yubo , Ha Sigaowa
Published: April 2020

The microRNA, miR-139-5p, has been proved to play important roles in regulating tumor progression, including prostate cancer, osteosarcoma, esophageal cancer, and so on, but its correlation of hepatocellular carcinoma (HCC) still remains unclear. Here we found that hsa-miR-139-5p (miR-139-5p) was decreased in HCC samples compared with normal liver tissues, and a lower expression of miR-139-5p was connected to a poorer prognosis. Mechanism study indicated that a decreased/increased miR-139-5p could increase/decrease HCC cells invasion and proliferation capacities via increasing SLITRK4 expression, what’s more, the reverse assays also confirmed the conclusion when we knocked down SLITRK4 in the miR-139-5p low-expression cells. Luciferase assay confirmed that miR-139-5p could directly bind to the 3′UTR of SLITRK4 mRNA to regulate its expression. Together, these findings show the importance of miR-139-5p/SLITRK4 pathway in HCC growth and progression and may provide new targets for us to better arrange the progression of HCC.