bluuebunny/crossref_metadata_2025 huggingface dataset:
CONSTITUTIONAL FEATURES OF THE COURSE OF CHRONIC GASTRODODUDENITIS ASSOCIATED WITH H.PYLORI IN CHILDREN
Authors: Balko O.
Published: June 2020

As you know, from ancient times to the present day, an individual approach to the patient has been and remains the most relevant in the framework of diagnosis, treatment and prevention of disease. In the modern world, the use of this approach is called personalized medicine, that is, "a rapidly developing field of healthcare based on an integrated, coordinated and individual approach for each patient to analyze the occurrence and course of the disease." From the foregoing, it becomes apparent that taking into account the constitutional features of the patient in the framework of anthropological teaching is an integral component in the supervision of each specific patient. A considerable number of facts accumulated in modern literature, indicates the constitutional conditionality of the parameters of the human body at different levels. It is this approach in the study of a macroorganism that allows one to get a more complete picture of not only the whole variety of forms and factors of system variability, but also to reveal patterns between the individual somatic constitution of a person, that is, a somatotype, and its other systems, in particular the digestive system. In the development of chronic gastroduodenitis, the hereditary-constitutional factor is one of the most important.
Farewell to the Past Century?
Authors: Hordecki Bartosz
Published: June 2020

The Russian authorities, supported by the representatives of the Russian cultural circles, celebrated 2018 as a year of harmonious reception of their literary traditions. Accordingly, the 100th anniversary of Alexander Solzhenitsyn’s birth was included into the series of commemorations and jubilees, minimizing, however, the problem of the Russian literature’s profound heterogeneity and inconsistency. Disregarding differences between literary currents, equalizing various, often contradictory intellectual phenomena can manifest that the Russian authorities search for a kind of cultural synthesis which will become a solid foundation of the Russianness in the XXI century. Nevertheless, their integrative ambitions are some how static or demobilizing. Moreover, these seem to be based on the conviction that cultural policy is not about determining and enhancing directions of further literary development but about assimilating and even restricting various artistic forces and traditions.
O PERDÃO E A PROMESSA COMO MODOS DE PRESERVAÇÃO DO MUNDO EM HANNAH ARENDT
Authors: Silva Brito Carlos Fernando
Published: June 2020

Este trabalho possui como mote apresentar a importância dos conceitos de perdão e promessa da teoria da ação em Hannah Arendt, para a preservação do mundo. Num primeiro momento apresentaremos brevemente o conceito de mundo e sua direta relação com as reflexões fenomenológicas de Heidegger e Husserl, e em um segundo momento se fará a exposição os conceitos de ação, pluralidade e natalidade e sua relação com a irreversibilidade e imprevisibilidade no interior do pensamento de Arendt, isto para compreendermos como estes se relacionam com o conceito de mundo de Arendt. Por fim, a partir da compreensão da fragilidade da ação e consequentemente do mundo, evidenciaremos a importância dos conceitos de perdão e promessa como meios de remediar a contigencialidade da ação e forma de preservar a possibilidade existência do mundo. Deste modo, a hipótese conclusiva desta pesquisa é que apesar da autora não ter apontado textualmente para a relação que esta posta neste trabalho a viabilização dos conceitos de perdão e promessa é extremamente frutífera para pensarmos o espaço do agir político, ou seja, pensarmos o mundo, na sociedade pós-guerra.
A filosofia da existência de Kierkegaard: background da Hermenêutica de Hans-Georg Gadamer
Authors: Teixeira Natalia Mendes
Published: June 2020

Ao ressignificar os sentidos do que é compreender, a obra de Kierkegaard pode ser lida como uma sutil reação às respostas epistemológica dos neokantianos e idealista dos hegelianos ao problema do fundacionalismo. Gadamer não só entendeu isso como a partir dessa constatação fundamentou sua Filosofia Hermenêutica. Partindo dessa premissa, nos ocuparemos em demonstrar que para ambos nem a existência nem o processo hermenêutico podem ser pré-concebidos estrutural, abstrata e objetivamente de forma normativa. Para Kierkegaard, os aspectos internos da existência só podem ser descritos através da dialética da comunicação subjetiva e, para Gadamer, o acontecer hermenêutico perpassa pelo próprio processo dialógico entre um eu e um tu, situados temporal e finitamente na existência cujo fundamento da relação é ético-ontológico e não teórico-normativo, como queria a hermenêutica técnica baseada em pressupostos positivistas modelados pela dicotomia sujeito-objeto. A radicalização dos sentidos e movimentos do compreender, esboçadas por Kierkegaard, provocaram e influenciaram profundamente Gadamer. O dinamarquês torna-se um dos expressivos backgrounds de sua Hermenêutica tanto quanto o historicismo de Dilthey, a facticidade heideggeriana, a fenomenologia husserliana e o perspectivismo nietzscheano.
Entre bolhas e portas: um diálogo sobre a noção de intimidade entre Peter Sloterdijk e Gaston Bachelard
Authors: Carletti Renan Silva , Safra Gilberto
Published: June 2020

Este artigo pretende apresentar como a noção de “intimidade”, apresentada pelo filósofo alemão Peter Sloterdijk em sua obra “Esferas I – Bolhas”, foi desenvolvida em diálogo com o mesmo tema abordado em “A poética do espaço” de Gaston Bachelard. Desenvolveremos, inicialmente, como a intimidade é compreendida por cada autor e sua articulação com as concepções de “exterioridade” e “espaço”. Posteriormente, pela perspectiva do escritor Juliano Pessanha, assinalaremos a crítica à abordagem de Martin Heidegger que converge ambos autores e mostraremos consonâncias e divergências entre os mesmos. Por último, poderemos compreender como o “pensamento esferológico” do filósofo alemão guarda raízes nas reflexões sobre a imaginação e poesia do pensador francês.
FENOMENOLOGIA E RESISTÊNCIA EM LEVINAS
Authors: Scoralick Klinger
Published: June 2020

Os apontamentos feitos por Levinas em suas primeiras obras, em especial, voltam-se para análises fenomenológicas de elementos que evidenciam uma “posição” de hesitação ou de resistência em relação à ontologia e ao horizonte “sem saída” que nela se inscreve. De modo adverso, Levinas lança uma interrogação que acompanhará todo o seu percurso filosófico e que atinge o coração da filosofia: tudo é conação de ser? A crítica se endereça para uma fatalidade inscrita no estar aí abandonado às possibilidades do ser – estar atado à própria existência –, ou seja, à condição de esquiva impossível das fronteiras que o ser demarca. De tal modo, tem-se que a inamovibilidade, oriunda da presença do ser, interrompe a mobilidade dos entes. A proposta de Levinas indica que em meio ao ser há uma “luxação” ou uma necessidade de evasão em relação a si mesmo, um recuo. Pode-se notar, já em seus primeiros escritos, um aceno não apenas para a questão da “ética como filosofia primeira”, mas, também, para a questão sobre o político, que se delineia sob traços de um “não”, isto é, resistência.
CONTINUUM PASSADO-PRESENTE E FUTURO E O TEMPLO COMO SIMBOLISMO CÊNTRICO: A RELAÇÃO DA IDENTIDADE COLETIVA JUDAICA COM SUA FORMA SIMBÓLICA ESPACIAL RELIGIOSA
Authors: Lopes da Silva Diego
Published: June 2020

O presente artigo científico trata sobre a forma espacial do Templo como lugar sagrado, e que se tornou ao longo da história do povo um elo cultural em torno das suas práticas religiosas e também de resistência às sucessivas dominações que buscavam impor sua religião e seus costumes ao povo judeu. Os objetivos presentes na publicação visam compreender o processo de resistência cultural à dominação helenística e a forma simbólica espacial religiosa do Templo como elemento de coesão social, gerando no judeu o sentimento de pertencimento a sua nação - criação de uma identidade - através da religião e de aversão/resistência à tentativa de mudanças nos costumes religiosos e na ritualística em torno do território religioso sagrado do Templo. Busca-se a partir da ciência geográfica compreender a forma do Templo, como território religioso sagrado que serviu de construção (geo)simbólica de resistência cultural judaica à dominação estrangeira e preservação de sua identidade religiosa. Propõe-se neste estudo um modo de aproximar os campos científicos da Geografia, História e Ciências da Religião; assim como os subcampos da ciência geográfica especialmente as Geografias da Religião, Histórica e Cultural, que ao interagirem, podem nos fornecer elementos importantes para recriar e interpretar elementos passados que foram negligenciados, compreendendo a importância dos símbolos culturais e a força que exercem nas mentalidades – no caso desta tese, a “mentalidade judaica” (posto que a configuração simbólica de um território ambicionado trouxe, do passado, ecos até a contemporaneidade). Conclui-se que o estudo da Geografia da Religião e da Geografia Histórica nos leva ao entendimento de peculiaridades da religiosidade; auxiliando-nos a compreender como o judaísmo do séc. II a.C. que aparentemente; seria fechado ao diálogo com as culturas orientais pagãs, na verdade se serviu do hibridismo cultural para manter a sua identidade religiosa, resistindo às tentativas de unificação cultural, estando na figura da desterritorialização do culto o elemento chave para entendermos a nova espacialidade da adoração à divindade.
ESCRITURAS E ARTES: FORMAS SIMBÓLICAS RELIGIOSAS ESPACIAIS
Authors: Gomes dos Santos Silva Avacir
Published: June 2020

A categoria de espaço foi concebida quando o ser humano estabeleceu qualitativamente a diferenciação entre espaços sagrado e profano. Esta é a abordagem que norteia a escrita deste artigo a partir das contribuições teóricas de Eliade (2010), Rosendahl (2010), Corrêa (2007, 2013) Cassirer (1994) e Hobsbawm (2014). O nosso desafio é interpretar as formas simbólicas presentes na tradição religiosa das Folias de Reis. Dentre elas elegemos a “Visitação dos Magos”, retratada no Evangelho de Mateus e na tela de Albrecht Dürer (pintor renascentista alemão, do século 16). As re(invenções) dessa passagem bíblica contribuem para que o espírito natalino seja reatualizado, ritualisticamente, ao final e início de cada ano pelos devotos dos Santos Reis, os quais, guiados pela Estrala, acreditam na hierofania de Deus em forma de Menino.
A SANTIFICAÇÃO DAS HORAS ASSINALADAS PELO REBOAR DOS SINOS UNIDO AO RESSOAR DO ÓRGÃO E DO CANTAR DOS MONGES
Authors: Maia Fragoso Mauro
Published: June 2020

O canto gregoriano tem sido uma constante no Mosteiro de São Bento do Rio de Janeiro, desde a fundação do cenóbio, no final do século XVI até os primeiros anos do século XXI. Não obstante tratar-se de um estilo de música que a princípio deveria ser executado à capela, tal maneira de cantar está intimamente vinculado a dois elementos musicais: o sino e órgão de tubos. Para melhor compreensão desse estilo musical executado no seu devido tempo e espaço, é preciso contextualizá-lo na sua trajetória histórica, sem, no entanto, esquecer de sua fundamentação bíblica e mitológica. O canto sacro é considerado como parte integrante do Ofício Divino. Este, por sua vez, tem por finalidade louvar a Deus e, simultaneamente, a santificar as horas daquilo que hodiernamente é entendido como dia. Para tanto, esse estilo decanto sacro conta com a participação de dois instrumentos musicais: os sinos que sinalizando as horas litúrgicas, convida os fiéis à oração; e o órgão de tubos que sustentando as vozes daqueles que cantam no coro, ajuda a elevar suas orações à presença do Criador de toda sinfonia.
Recognising pain in dementia: what has changed?
Authors: Dening Karen Harrison
Published: June 2020

Pain is common among older people due to the increased prevalence of age-related conditions. However, this might be misidentified and poorly managed in those with dementia. Karen Harrison Dening presents effective diagnostic and treatment strategies
Parkinson's disease and the COVID-19 pandemic: responding to patient need with nurse-led telemedicine
Authors: Thomas Sue , Mancini Francesca , Ebenezer Louise , Price Jane , Carta Tania , Cordasco Jessica , Tedesco Chiara , Gillett Sarah
Published: June 2020

With the COVID-19 pandemic limiting face-to-face interaction, the drive for innovation and the need to develop alternative solutions to patient engagement, treatment and diagnosis has been suddenly accelerated. Sue Thomas and national and international colleagues outline a novel technological initiative launched in Italy to cope with the pressures of the pandemic, providing inspiration for similar future projects in the UK
Numerical modeling of integrated electro-optic modulators based on mode-gap shifting in photonic crystal slab waveguides containing a phase change material
Authors: Ghosh Rajib R. , Bhardwaj Priyanka , Dhawan Anuj
Published: June 2020

This paper presents novel designs and simulation results of electro-optic modulators in integrated silicon photonics platforms. The electro-optic modulators described in this paper are based on the modulation of the photonic bandgap in a silicon photonic crystal slab waveguide, consisting of a phase change material (germanium selenide) sandwiched in between silicon layers. Three-dimensional finite difference time domain (FDTD) modeling is employed to simulate two configurations of electro-optic modulators based on mode-gap shifting in photonic crystal slab waveguides—one that is designed for operation with the transverse electric (TE) polarization of light and the other for the transverse magnetic (TM) polarization. When the electric field is applied across the germanium selenide layer surrounded by doped silicon layers, there is a change of phase of the germanium selenide layer. A large refractive index contrast between the two phases of the germanium selenide layer—i.e., between the amorphous phase and the crystalline phase—on application of the electric field is responsible for shifting of the mode gap in the dispersion characteristics of the PhC slab waveguide. Our results show excellent performance of the electro-optic modulators in terms of the high On/Off extinction ratio (

>

37

d
B

in the TE configuration and

>

28

d
B

in the TM configuration), broadband switching capability (

∼

100

n
m

), low insertion loss in the On state (

<

2

d
B

), high range of tunability (by changing the lattice constant and radius of air holes), and low operating voltage (

<

4

V

). The proposed devices can be used as electro-optic modulators in future nanoscale photonic integrated circuits.
Parallel feature based calibration method for a trinocular vision sensor
Authors: Shao Mingwei , hu Mengjie
Published: June 2020

In this paper, a new method to calibrate a trinocular vision sensor is presented. A planar target with several parallel lines is utilized. The trifocal tensor of three image planes can be calculated out according to line correspondences. Compatible essential matrix between each two cameras can be obtained. Then, rotation matrix and translation matrix can be deduced base on singular value decomposition of their corresponding essential matrix. In our proposed calibration method, image rectification is carried out to remove perspective distortion. As the feature utilized is straight line, precise point to point correspondence is not necessary. Experimental results show that our proposed calibration method can obtain precise results. Moreover, the trifocal tensor can also give a strict constraint for feature matching as descripted in our previous work. Root mean square error of measured distances is 0.029 mm with regards to the view field of about 250×250 mm. As parallel feature exists widely in natural scene, our calibration method also provides a new approach for self-calibration of a trinocular vision sensor.
Modal analysis of photonic and plasmonic resonators
Authors: Zimmerling Jörn , Remis Rob
Published: June 2020

Determining the electromagnetic field response of photonic and plasmonic resonators is a formidable task in general. Field expansions in terms of quasi-normal modes (QNMs) are often used, since only a few of these modes are typically required for an accurate field description. We show that by exploiting the structure of Maxwell’s equations, conjugate-symmetric frequency-domain field expansions can be efficiently computed via a Lanczos-type algorithm. Dominant QNMs can be identified a posteriori with error control and without a priori mode selection. Discrete QNM approximations of resonating nanostructures are presented and the spontaneous decay rate of a quantum emitter is also considered.
Critical pattern selection method for full-chip source and mask optimization
Authors: Liao Lufeng , Li Sikun , Wang Xiangzhao , Zhang Libin , Gao Pengzheng , Wei Yayi , Shi Weijie
Published: June 2020

Source and mask optimization (SMO) is one of the most important resolution enhancement techniques for integrated circuit manufacturing in 2X nm technology node and beyond. Nowadays full-chip SMO is alternatively realized by applying SMO to limited number of selected critical patterns instead of to full-chip area, since it is too computational expensive to be apply SMO in full-chip area directly. The critical patterns are selected by a pattern selection method which enables SMO in full-chip application by balancing the performance and computation consumption. A novel diffraction-based pattern selection method has been proposed in this paper. In this method, diffraction-signatures are sufficiently described with widths in eight selected directions. Coverage rules between the diffraction-signatures are specifically designed. Diffraction-signature grouping method and pattern selection strategy are proposed based on the diffraction-signatures and coverage rules. A series of simulations and comparisons performed using ASML’s Tachyon software, which is one of the state of the art commercial SMO platforms, verify the validity of the proposed method.
Phase extraction neural network (PhENN) with coherent modulation imaging (CMI) for phase retrieval at low photon counts
Authors: Kang Iksung , Zhang Fucai , Barbastathis George
Published: June 2020

Imaging with low-dose light is of importance in various fields, especially when minimizing radiation-induced damage onto samples is desirable. The raw image captured at the detector plane is then predominantly a Poisson random process with Gaussian noise added due to the quantum nature of photo-electric conversion. Under such noisy conditions, highly ill-posed problems such as phase retrieval from raw intensity measurements become prone to strong artifacts in the reconstructions; a situation that deep neural networks (DNNs) have already been shown to be useful at improving. Here, we demonstrate that random phase modulation on the optical field, also known as coherent modulation imaging (CMI), in conjunction with the phase extraction neural network (PhENN) and a Gerchberg-Saxton-Fienup (GSF) approximant, further improves resilience to noise of the phase-from-intensity imaging problem. We offer design guidelines for implementing the CMI hardware with the proposed computational reconstruction scheme and quantify reconstruction improvement as function of photon count.
Manifestation of extremely high-Q pseudo-modes in scattering of a Bessel light beam by a sphere
Authors: Klimov Vasily
Published: June 2020

The exact analytical solution of Maxwell equations for a Bessel light beam scattered by a sphere is found. Scattered power, stored energy, and a generalized

Q

factor as a function of frequency, the sphere radius, permittivity, and the Bessel beam angle are found. On the basis of this solution, modes and pseudo-modes of a dielectric sphere are extracted by calculation of the generalized

Q

factor. It is shown that an appropriate choice of Bessel beam parameters can provide excitation of a single given mode and an unlimited value of the radiative

Q

factor of pseudo-modes.
Hertz-level frequency comparisons between diverse color lasers without a frequency comb
Authors: Bourbeau Hébert Nicolas , Hilton Ashby P. , Light Philip S. , Luiten Andre N.
Published: June 2020

We present a simple yet powerful technique to measure and stabilize the relative frequency noise between two lasers emitting at vastly different wavelengths. The noise of each laser is extracted simultaneously by a frequency discriminator built around an unstabilized Mach–Zehnder fiber interferometer. Our protocol ensures that the instability of the interferometer is canceled and yields a direct measure of the relative noise between the lasers. As a demonstration, we measure the noise of a 895 nm diode laser against a reference laser located hundreds of nm away at 1561 nm. We also demonstrate the ability to stabilize the two lasers with a control bandwidth of 100 kHz using a Red Pitaya and reach a sensitivity of

1

H

z

2

/

H
z

limited by detector noise. We independently verify the performance using a commercial frequency comb. This approach stands as a simple and cheap alternative to frequency combs to transport frequency stability across large spectral intervals or to characterize the noise of arbitrary color sources.
Contribución al catálogo del escultor Felipe de Espinabete (1719-1799)
Authors: Baladrón Alonso Javier
Published: June 2020

Con motivo del Tercer Centenario del nacimiento del escultor Felipe de Espinabete (1719-1799), uno de los más conspicuos maestros del Rococó castellano, el presente artículo quiere dar a conocer una serie de nuevas atribuciones que aumentarán sensiblemente su catálogo productivo.
Salvador Azpiazu y José Gestoso en La ilustración artística. Relaciones personales y profesionales
Authors: Ramos Suárez Manuel Antonio , Ramos Alfonso Ramón
Published: June 2020

En este artículo se analizan los trabajos realizados por el ilustrador Salvador Azpiazu junto con el escritor sevillano José Gestoso en La Ilustración Artística, revista de crónicas de fines del siglo XIX. Gracias a la correspondencia conservada, así como a la documentación contable de la editorial barcelonesa Montaner y Simón se pueden establecer relaciones personales y profesionales entre ambos.
Esa pareja feliz (1951) de Berlanga y Bardem y sus referentes cinematográficos y literarios
Authors: Sojo Gil Kepa Inazio
Published: June 2020

Esa pareja feliz es una película clave para comprender el cine disidente al franquismo que reacciona ante el panorama cinematográfico de la postguerra española. Sobre este filme se ha hablado mucho, pero nadie ha analizado los referentes cinematográficos y literarios que inspiraron a Berlanga y Bardem. Tan sólo han aparecido esos referentes citados por los propios directores en algunas publicaciones antiguas. Este artículo pretende analizar, el grado de influencia cinematográfica y literaria recibida por Esa pareja feliz, así como la repercusión ejercida por este filme en obras posteriores.
Natural kinds: a new synthesis
Authors: Barberousse Anouk , Longy Françoise , Merlin Francesca , Ruphy Stéphanie
Published: June 2020

What is a natural kind? This old yet lasting philosophical question has recently received new competing answers (e.g., Chakravartty, 2007; Magnus, 2014; Khalidi, 2013; Slater, 2015; Ereshefsky Reydon, 2015). We show that the main ingredients of an encompassing and coherent account of natural kinds are actually on the table, but in need of the right articulation. It is by adopting a non-reductionist, naturalistic and non-conceptualist approach that, in this paper, we elaborate a new synthesis of all these ingredients. Our resulting proposition is a multiple-compartment theory of natural kinds that defines them in purely ontological terms, clearly distinguishes and relates ontological and epistemological issues - more precisely, two grains of ontological descriptions and two grains of explanatory success of natural kinds -, and which sheds light on why natural kinds play an epistemic role both within science and in everyday life.
Postobesity Surgery Esophageal Dysfunction: A Combined Cross-Sectional Prevalence Study and Retrospective Analysis
Authors: Miller Alexander T. , Matar Reem , Abu Dayyeh Barham K. , Beran Azizullah , Vela Marcelo F. , Lacy Brian E. , Crowell Michael D. , Geno Debra M. , Lavey Crystal J. , Katzka David A. , Ravi Karthik
Published: June 2020

INTRODUCTION:

Esophageal dysmotility including features of achalasia may develop because of bariatric surgery. However, the prevalence of these complications is unknown. We sought to define the prevalence of dysphagia and major esophageal motility disorders including achalasia after bariatric surgery through a large retrospective database review.

METHODS:

Patients with a history of laparoscopic sleeve gastrectomy or Roux-en-Y gastric bypass who underwent a diagnostic high-resolution impedance manometry (HRIM) either before or after bariatric surgery across 3 large tertiary referral sites from June 2012 through February 2019 were identified from a procedural database. HRIM studies were interpreted per the Chicago classification v3.0 by a blinded investigator (K.R.). Demographic/clinical features were collected. In addition, patients who underwent bariatric surgery from January 2014 to April 2015 were contacted and administered a validated symptom assessment survey to gauge the overall prevalence of dysphagia in a postbariatric population.

RESULTS:

A total of 137 patients were identified, including 97 who underwent HRIM after bariatric surgery (laparoscopic sleeve gastrectomy [n = 39, 40.1%]; Roux-en-Y gastric bypass [n = 58, 59.8%]) at a median of 5.84 years (interquartile range 2.1–12.5) postoperatively and 40 preoperative bariatric surgery candidates with medically complicated obesity. A manometric pattern consistent with achalasia was identified in 7 (7.2%) postsurgical patients compared with none in the preoperative group (P = 0.08). We further identified a separate achalasia-like pattern defined by aperistalsis and increased intragastric pressure (postobesity surgery esophageal dysfunction [POSED]) in 5 (5.2%) postsurgical patients vs none found preoperatively (P = 0.14). Achalasia or POSED was associated with postbariatric surgery (12.4% vs 0%, P = 0.02). Increasing time since surgery was independently associated with the development of achalasia (median 12.5 vs 5.8 years, P = 0.02), POSED (median 15.0 vs 5.8 years, P = 0.02) and major motility disorders (6.6 vs 4.9 years, P = 0.01). Furthermore, among 271 postbariatric surgery patients contacted for symptom assessment via survey, the prevalence of dysphagia was 13.7% at a mean 3.9 years after surgery.

DISCUSSION:

Postoperative dysphagia is a common long-term complication of bariatric surgery. This is potentially the consequence of a time-dependent association with the development of postoperative esophageal dysmotility, particularly achalasia and POSED. Consequently, esophageal dysmotility may be an important under-recognized complication of bariatric surgery.
AVALIAÇÃO RETROSPECTIVA DA URINÁLISE E MENSURAÇÃO DE CREATININA SÉRICA COMO MÉTODOS AUXILIARES NO DIAGNÓSTICO DE DOENÇA RENAL CRÔNICA EM PACIENTES CANINOS
Authors: Pereira Sergiane Baes , Grol Aline Van , Conte Camila , Gil Luciana Fernandes Aquini , Krause Luis Eduardo Barcellos , Meinerz Ana Raquel Mano
Published: June 2020

A doença renal crônica (DRC) apresenta elevados índices de morbidade em pacientes caninos, e os exames complementares possuem grande relevância para o diagnóstico, destacando-se a urinálise e a mensuração de creatinina sérica nesse sentido. Este trabalho teve como objetivo avaliar a casuística das solicitações de urinálise e mensurações de creatinina sérica em um laboratório clínico veterinário e correlacionar os achados destes testes com a suspeita clínica de disfunção renal crônica em pacientes caninos. Consistiu em um estudo retrospectivo transversal realizado no Laboratório de Patologia Clínica Veterinária da Universidade Federal de Pelotas (LPCVet-UFPEL). As variáveis de interesse foram as solicitações de urinálise e mensuração sérica de creatinina, a suspeita clínica de DRC e os resultados das análises realizadas em um período de quatro anos. Os dados foram avaliados por análise descritiva utilizando o programa EpiInfoTM. Foram observadas 2.157 solicitações para avaliação de creatinina sérica e 586 solicitações de urinálise, sendo que destas, 1,48% (32/2.157) e 2,90% (17/586) apresentavam suspeita clínica de DRC, respectivamente. Dentre as avaliações de creatinina sérica, 8,48% (183/2.157) apresentaram azotemia, enquanto nas avaliações de urinálise, 21,67% (127/586) apresentaram alterações. Houve solicitação concomitante de urinálise e mensuração de creatinina sérica em 12,37% (267/2.157) dos exames, sendo que em 18,35% (49/267) houve alterações apenas na urinálise e em 17,60% (47/267) houve alterações em ambos os resultados. Pode-se concluir que apesar de o número de solicitações para avaliação de creatinina sérica ter sido superior ao número de solicitações de urinálise, as urinálises apresentaram maior número de resultados indicativos de DRC.
TRANSFORMAÇÕES SOCIOECONÔMICAS E DE PRODUÇÃO DE UNIDADES DE PRODUÇÃO LEITEIRA (UPLS) DE UMA COOPERATIVA NA REGIÃO SUL DO RIO GRANDE DO SUL
Authors: Zani João Luíz , Peter Cristina Mendes , Krummmenauer Amanda
Published: June 2020

A produção leiteira é uma das atividades mais importantes do setor agropecuário no Brasil e no Rio Grande do Sul. Objetivou-se neste estudo realizar um levantamento socioeconômico e produtivo de Unidades de Produção Leiteira (UPLs) assistidas pela Cooperativa de Pequenos Produtores de Leite da Região Sul (COOPAL) no estado do Rio Grande do Sul, além de analisar suas transformações em um intervalo de 13 anos. Para isto, foram aplicados questionários a 188 produtores nos anos 2000 e 2013. Destes, 53,2% (100) abandonaram a atividade durante o período. A maioria dos produtores não completou o primeiro grau, o número de analfabetos foi reduzido para zero, e houve aumento nos demais níveis de escolaridade. O volume diário de leite produzido por UPL variou positivamente. Houve incremento na qualidade e variedade dos alimentos ofertados aos animais, sendo as principais formas de oferta: pastagem de campo nativo, pastagem cultivada, milho e sal mineral. O resfriamento do leite de forma adequada à legislação aumentou, sendo utilizados principalmente tanques de imersão. O número de produtores com ordenhadeira mecânica aumentou de 9,09% para 48,86% (p<0,0001), porém a ordenha manual foi a principal utilizada. Houve um incremento no número de produtores que recebem algum tipo de assistência técnica, de 19 para 63 (p<0,0001). Acredita-se ter sido fundamental aos produtores que permaneceram na atividade a adaptação e adesão às tecnologias para atender ao aumento de exigências do mercado leiteiro.
Platelet parameters in Chinese older adults with metabolic syndrome
Authors: Yang Xue-Jiao , Zhang Le-Yang , Ma Qing-Hua , Sun Hong-Peng , Xu Yong , Chen Xing , Pan Chen-Wei
Published: June 2020

Purpose:

We aimed to examine the associations of platelet parameters with the presence of metabolic syndrome in community-dwelling older Chinese adults.

Methods:

Study sample was from the Weitang Geriatric Diseases Study, which included 4338 individuals aged 60 years or above. The mean age of the participants was 68 years. Metabolic syndrome was defined based on the Adult Treatment Panel III criteria. Platelet parameters were assessed using an automated hematology analyzer. Multiple logistic regression models were fitted to examine relationships between the platelet parameters and the presence of metabolic syndrome after adjusting for potential confounders.

Results:

The adjusted odds ratio (95% CI) of metabolic syndrome for the highest quartile of platelet parameters (platelet count, mean platelet volume, plateletcrit, platelet distribution width, platelet larger cell ratio) when compared to the lowest quartile were 1.32 (1.06, 1.64), 1.00 (0.81, 1.24), 1.37 (1.10, 1.71), 1.45 (1.14, 1.83), 1.11 (0.89, 1.39), respectively. Hypertension and diabetes modified the relationship between platelet distribution width and metabolic syndrome with the associations being significant in hypertensive and non-diabetic groups. The levels of platelet distribution width increased with the risk of metabolic syndrome in men but not in women.

Conclusion:

The levels of platelet count, plateletcrit and platelet distribution width increased in older adults with metabolic syndrome, suggesting that these parameters may be useful biomarkers for further risk appraisal of metabolic syndrome in aged population.
Homozygous p.Val89Leu plays an important pathogenic role in 5α-reductase type 2 deficiency patients with homozygous p.Arg246Gln in SRD5A2
Authors: Arya Sneha , Tiwari Ankita , Lila Anurag Ranjan , Sarathi Vijaya , Bhandare Vishwambhar Vishnu , Kumbhar Bajarang Vasant , Rai Khushnandan , Kunwar Ambarish , Thakkar Hemangini , Thakkar Kunal , Memon Saba Samad , Patil Virendra , Khadilkar Kranti , Jadhav Swati S , Shah Nalini S , Bandgar Tushar
Published: June 2020

Objective:

To evaluate the pathogenic role of a few benign variants and hypomorphic pathogenic variants in SRD5A2.

Design and methods:

We retrospectively analyzed phenotypes and genotypes in 23 Indian patients with genetically proven steroid 5α-reductase 2 (SRD5A2) deficiency. The interactions of the SRD5A2 enzymes resulting due to the most common benign variant (p.Val89Leu), the most common (hypomorphic) pathogenic variant (p.Arg246Gln) and the double variants (p.Val89Leu and p.Arg246Gln) in SRD5A2 were compared with that of the wild type (WT) enzyme by molecular dynamics (MD) simulation.

Results:

The majority (n = 19, 82.61%) of patients presented for atypical genitalia and had male gender identity (16/20). Including the two novel ones (p.Leu83Pro, p.Ala28Leufs*103), a total of nine different pathogenic variants were observed. p.Arg246Gln was the most common pathogenic variant (n = 12). Homozygous p.Arg246Gln (n = 9) variant was associated with milder undervirilization (Sinnecker score of ≤3a: 8/9 vs 6/14, P = 0.04) and had concurrent homozygous p.Val89Leu in all patients. Interestingly, asymptomatic fathers of two index patients were homozygous for p.Arg246Gln which questioned the pathogenicity of the variation as a sole factor. Unlike all symptomatic homozygous p.Arg246Gln patients who were also homozygous for p.Val89Leu, asymptomatic homozygous p.Arg246Gln fathers were heterozygous for p.Val89Leu. On MD simulation SRD5A2 p.Val89Leu-Testeosterone (T) and SRD5A2 p.Arg246Gln-T complexes, but not SRD5A2 p.Val89Leu and p.Arg246Gln-T complex, demonstrated close interaction between NADPH and T as that of SRD5A2 WT-T.

Conclusions:

p.Arg246Gln may not be pathogenic as a sole variation even in the homozygous state; additional contribution of homozygous p.Val89Leu variant may be essential for the pathogenicity of p.Arg246Gln in SRD5A2.
La responsabilidad social empresarial en el área medioambiental: una obligación constitucional en Colombia
Authors: Correal Torres Paula Nathalia
Published: June 2020

Las prácticas socialmente responsables se establecen como obligación constitucional para dar cumplimiento a los principios de función social y ecológica de la empresa, y se traducen en preservación de recursos naturales, en protección a la biodiversidad y en garantía de derechos humanos como la salud y el medioambiente sano. Estos derechos consagrados no solo en la Carta Magna, sino en instrumentos internacionales se constituyen como compromisos del Estado, cuyo incumplimiento puede derivar en responsabilidad de él mismo ante escenarios internacionales. La afirmación sobre la obligatoriedad en el cumplimiento de la Responsabilidad Social Empresarial en el área medioambiental se sustenta en el constitucionalismo principialista, que defiende la obligatoriedad de la totalidad del texto constitucional y exige un camino para garantizar los derechos y principios allí reconocidos. Este artículo construye un criterio de interpretación respecto de la obligatoriedad de la figura de la Responsabilidad Social Empresarial en el área medioambiental, a partir del análisis de normativa nacional, esencialmente de la Constitución Política de Colombia, y de normativa internacional, estudiando aquellos instrumentos que regulan la protección del medioambiente.
Aspects to Consider for Clinical Simulation Instances During COVID-19 Pandemic
Authors: Durán Ojeda Gerardo
Published: June 2020

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Struktur dan Kepadatan Vegetasi Mangrove di Teluk Kupang
Authors: - Rusydi , - Ihwan , - Suaedin
Published: June 2020

Vegetasi mangrove merupakan komunitas tumbuhan yang hidup di zona pasang surut di sepanjang garis pantai dan dipengaruhi  oleh  kualitas  lingkungan.  Meningkatnya  kebutuhan  manusia  menyebabkan  banyaknya  hutan  mangrove  yang ditebang, diubah untuk berbagai kepentingan seperti pertambakan, pemukiman dan fasilitas–fasilitas pelabuhan.Teluk Kupang memiliki wilayah pesisir yang cukup kaya sumber daya, salah satunya adalah hutan mangrove.Tujuan penelitian ini adalah untuk mengetahui  jenis  dan nilai  kerapatan, frekwensi, dominansi  dan INP mangrove  di Teluk Kupang.  Pengambilan  data menggunakan metode Petak Contoh (Transect Line Plot) dengan menghitung jumlah spesies (pohon, anakan dan semai), jumlah  individu  masing-masing  spesies,    persentase  tutupan,  lingkar  batang  dan  menganalisis  untuk  mendapatkan  nilai kerapatan, frekwensi, dominansi dan INP(Indeks Nilai Penting). Hasil penelitian menunjukkan bahwa pada 4 (empat) lokasi pengamatan, ditemukan sebanyak 11 jenis mangrove. Adapun 11 jenis mangrove yang ditemukan adalah; Rhizopora apiculata, Rhizopora mucronata, Rhizopora stylosa, Burguiera gymnorrhiza, Osbornia octodanta, Avicennia officinalis, Avicennia marina, Scyphiphora  hydrophyllaceae,  Lumnitzera  racemosa,  Sonneratia  alba  dan  Aegiceras  corniculatum.  Jenis  mangrove  yang memiliki indeks nilai penting tertinggi untuk tingkatan pohon yaitu Rhizopora mucronata (INP :299,6) dan terendah adalah Rhizopora stylosa (INP : 18,5), untuk tingkatan pancang/anakan jenis mangrove yang memiliki indeks nilai penting tertinggi sekaligus terendah adalah Rhizopora apiculata (INP : 202 dan 39,62). Sedangkan untuk tingkatan semai, jenis yang memiliki indeks nilai penting tertinggi yaitu Soneratia alba (INP : 174) dan terendah adalah Burguiera gymnorrhiza dan Scyphiphora hydrophyllaceae (INP : 11,80).
Aggressive but loyal
Authors: Poynter Elizabeth
Published: June 2020

Language powerfully impacts the construction of our gender identities. In the mid-twentieth century gender stereotypes were strong, but at the same time feminism was giving rise to new ideas and becoming increasingly mainstream. What gender-related discourse prosodies did children encounter in popular literature? Did these merely reinforce the conventional stereotypes or did they contain the seeds of change? This study of British children's fiction published in the 1940s-60s seeks to answer these questions through an analysis of personality descriptors collocated with female and male characters in eight books by four prolific children's writers. Although gender stereotypes (as represented by the Bem Sex-Role Inventory) are to some extent reinforced in these books, there are also considerable discrepancies. Children were meeting a range of positive models which did not always match ‘feminine' or ‘masculine' stereotypes.
Language, indexicality and gender ideologies
Authors: Levon Erez , Ye Yang
Published: June 2020

It is well established that listeners’ attitudes to variability in language are affected by context. One speaker’s use of a particular form will not necessarily be evaluated in the same way as another’s use of that same form, and the pragmatic meanings listeners associate with speech depend on the specific social setting in which that speech occurs. In this article, we explore how this contextual sensitivity of sociolinguistic perception interacts with broader ideologies about gender. Specifically, we examine how the use of ‘uptalk’, or rising final intonation on declarative utterances, impacts the perceived credibility of women versus men in different legal contexts, including those characterized by strong ideologies of gender (e.g. a rape trial) and those in which that ideological framing is less pronounced (e.g. a medical malpractice trial). Our goal is to identify how social ideologies about gender affect listeners’ perceptions of uptalk, and to explore the ramifications that these perceptions have on women’s ability to be believed in a courtroom.
Uso de telessaúde por alunos de graduação em Fonoaudiologia: Possibilidades e perspectivas em tempos de pandemia por COVID-19
Authors: Fernandes Fernanda Dreux Miranda , Lopes-Herrera Simone Aparecida , Perissinoto Jacy , Molini-Avejonas Daniela Regina , Tamanaha Ana Carina , Souza Ana Paula Ramos de , Amato Cibelle Albuquerque de la Higuera , Montenegro Ana Cristina Albuquerque , Machado Fernanda Prada , Segeren Leticia , Goulart Bárbara Niegia Garcia de
Published: June 2020

A pandemia da COVID-19 trouxe desafios e necessidade de adaptação em diversas frentes. A atualização das formas de trabalho é necessária e promover ensino e atendimento no setor saúde condizentes com o século XXI é fundamental. Não estamos apenas tratando da formação de graduandos na área de Fonoaudiologia, mas do atendimento clínico a uma parcela significativa da população que depende dos serviços de clínicas-escola vinculadas às universidades e centros de formação em nossa profissão.Neste texto traremos algumas reflexões sobre a relevância do uso das tecnologias de telessaúde para a formação de fonoaudiólogos, considerando a articulação entre as diretrizes curriculares nacionais, a formação profissional e aspectos éticos.
Towards Omni-Supervised Face Alignment for Large Scale Unlabeled Videos
Authors: Zhu Congcong , Liu*(corresponding author) Hao , Yu Zhenhua , Sun Xuehong
Published: June 2020

In this paper, we propose a spatial-temporal relational reasoning networks (STRRN) approach to investigate the problem of omni-supervised face alignment in videos. Unlike existing fully supervised methods which rely on numerous annotations by hand, our learner exploits large scale unlabeled videos plus available labeled data to generate auxiliary plausible training annotations. Motivated by the fact that neighbouring facial landmarks are usually correlated and coherent across consecutive frames, our approach automatically reasons about discriminative spatial-temporal relationships among landmarks for stable face tracking. Specifically, we carefully develop an interpretable and efficient network module, which disentangles facial geometry relationship for every static frame and simultaneously enforces the bi-directional cycle-consistency across adjacent frames, thus allowing the modeling of intrinsic spatial-temporal relations from raw face sequences. Extensive experimental results demonstrate that our approach surpasses the performance of most fully supervised state-of-the-arts.
Great Western railway electrification, UK: Patchway tunnels
Authors: Fletcher Nigel , Brown Matthew , Sadek Tarek
Published: June 2020

The Patchway rail tunnels in Bristol were a major obstacle to the £3 billion electrification of the Great Western railway between London and south Wales, completed in December 2019. The tracks in the three nineteenth-century brick-arch tunnels needed to be lowered to provide the required clearances for new overhead line equipment. Extensive surveys, stability analyses and strengthening measures were undertaken to ensure structural integrity was maintained during the track lowering. An overhead conductor bar was developed specifically for the tunnels to reduce the lowering required. Further innovation included specially adapted drilling rigs to enable the efficient installation of tunnel fixings. This paper focuses on the civil engineering aspects of the project, with an overview of the electrification design to demonstrate how the overall integrated solution was achieved.
What Is the Impact of the Flipping the Classroom Instructional e-Learning Model on Teachers
Authors: De Jaegher Lut
Published: June 2020

Flipping the classroom is an instructional model in which students learn basic subject knowledge prior to the face-to-face class moment, where they can have active learning experiences with their peers and teachers. Research revealed the positive effects for students, who can learn at their own pace, reach up to the highest level of the thinking skills of Bloom’s taxonomy, exercise and improve their collaboration, communication and ICT skills. Where most of the research concentrates on the learning effects for the students, this paper presents the results of recent European research on the impact for teachers. Setting up a learning path for flipped classroom, is a big challenge. Together with 7 European partners from Belgium, Italy, Bulgaria, Slovenia, Poland and the Netherlands, we did research on how students and teachers perceive the implementation of the flipped classroom model in their teaching and how challenging the integration of technology in their lessons is. We also asked about their perceptions: are the benefits worth the efforts, is the flipped classroom model improving their teaching skills and what are their needs and requirements to get succeed? We started by getting the teachers a flipped classroom instruction to learn the method, combined with a face-to-face training in Belgium, where they were supported to create a flipped classroom learning path for their own subjects and classes. Then, they implemented the method in their institutions for adult and higher education. The surveys were conducted after this try out, in all of the 7 European participating countries. The research results of the surveys will be presented and used to make recommendations that increase the chance of a successful implementation of the flipped classroom method. These recommendations were tested and evaluated during flipped classroom trainings at teacher training departments in Belgium and Vietnam. The qualitative test results will also be presented in this paper.
Developing an Interdisciplinary Bio-Sensor STEM Module for Secondary School Teachers: An Exploratory Study
Authors: Hsu Shihkuan , Sung Chia-Chi , Sheen Horn-Jiunn
Published: June 2020

Educators have suggested that citizens need the ability to engage in self-directed inquiry and problem solving. In line with the trend, current reforms in Taiwanese schools advocate the development of these core competencies. One way to achieve this goal is through STEM education. STEM modules which integrate science, math, technology, and engineering have become a prime catalyst for inquiry-based multidisciplinary teaching and learning. Although the demands and the benefits of STEM modules are often highlighted, the challenges of the development and implementation of such an interdisciplinary module are less discussed. This paper describes the process of the development of a bio-sensor module that uses Arduino to analyze glucose level of concentration.This multidisciplinary module integrates physics, chemistry, biology, mathematics, electronics, and programming. The goal of the program is for students to construct a device that imitates a commercial glucose meter. Teacher workshops were conducted for educators to learn the concepts and the procedures. A set of questionnaires collected from 21 workshop participants revealed that teachers face various challenges in the process of understanding and modifying the STEM module, as well as preparing students so they are ready to learn with the module. A group interview after the workshop revealed the teachers’ difficulties in implementing a module that requires advanced technical skills and materials. The potential usefulness for the students, and the emergence of a different goal than the original plan, provide challenging and enlightening lessons. Rather than an engineering-centered model, this study proposes an alternative science-centered model for STEM material development.