bluuebunny/crossref_metadata_2025 huggingface dataset:
La transformación digital en el turismo: un modelo desde la construcción social de la tecnología (SCOT)
Authors: Toscano-Jara Johanna , Loza-Aguirre Edison , Franco-Crespo Antonio
Published: September 2023

La transformación digital (TD) es un proceso tecnológico que ha impactado las estructuras y prácticas de las organizaciones. Dentro de estas, se encuentran las organizaciones turísticas que desde el auge del Internet han evolucionado su modelo de negocios y su forma de co-crear experiencias con los consumidores turísticos. El entorno turístico cada vez integra innovaciones tecnológicas para generar nuevas experiencias digitales, lo que demanda una coordinación especializada entre las capacidades de las organizaciones y los intereses de varios grupos en la actividad turística. El objetivo de este estudio es profundizar sobre la TD de la industria turística desde un enfoque de la construcción social de la tecnología (SCOT), para canalizar una visión integral del proceso. Para esto se realizó una revisión sistemática de literatura, cuyos hallazgos guiaron la construcción de un modelo de la transformación digital en el turismo con un enfoque SCOT (modelo SCOT-TDTUR).
Las prácticas no éticas en favor de la organización analizadas desde perspectiva del poder del contexto, organizaciones e individuos
Authors: Reynoso Espinoza Deivit
Published: September 2023

El artículo aborda de manera teórica la relación entre el poder del contexto, las organizaciones y los individuos, y su impacto en la adopción y aceptación de prácticas no éticas en beneficio de una entidad organizativa. Se introduce el término "ética gris" para describir a esas prácticas que, pese a transgredir normativas sociales y en ocasiones legales, son toleradas. Este fenómeno es explorado desde la perspectiva de la influencia bidireccional de esos niveles de análisis. En una primera instancia, se examina cómo el contexto organizacional establece un marco institucionalizado que consolida y facilita la difusión de dichas prácticas. Posteriormente, se profundiza en la organización misma, analizando los roles y funciones que inciden en la elección de esas prácticas en favor de la organización. Por último, se explora la influencia ejercida por los individuos y las fuerzas que los guían, posibilitando la adopción de estas prácticas. Estos puntos se discuten siguiendo la revisión de investigaciones relativas ubicadas en fuentes académicas relevantes.
Estudio piloto sobre la producción de /ɾ/ en posición de coda en el español de Hornos de Segura (Jaén)
Authors: Company Almagro Rebeca
Published: September 2023

Este estudio piloto investiga la producción de la vibrante simple en el español de Hornos de Segura, en la provincia de Jaén (España). Para analizar cómo es la producción de /ɾ/ en este dialecto, se diseña una encuesta en Qualtrics que consta de cuatro preguntas de trasfondo, diez oraciones y diez fotos, dirigida a nueve nativos de Hornos de Segura pertenecientes a dos grupos de edad distintos. Las grabaciones recogidas se analizan con Praat (Boersma & Weenink, 2022) para responder a las siguientes preguntas de investigación: (1) ¿Cuáles son los alófonos de /ɾ/ en Hornos de Segura? y (2) ¿En qué contextos se lateraliza la /ɾ/ en este dialecto? Los resultados muestran que los hablantes de este dialecto producen cinco alófonos de /ɾ/, incluyendo lateralizado (Ramos-Pellicia, 2004) y variante mixta (Ruiz-Peña, 2013). Además, se observa una diferencia en los contextos de lateralización de /ɾ/: Los más jóvenes tienden lateralizan la vibrante cuando va seguida de consonante y los mayores cuando a esta le sigue una pausa.
Dinero móvil y su impacto en la inclusión financiera en los residentes de los distritos de Lima Norte en el 2021
Authors:   , García Bendezú Estefany Johana
Published: September 2023

La presente investigación tiene como finalidad determinar el impacto del dinero móvil en la inclusión financiera en los residentes de los distritos de Lima Norte en el 2021. El motivo por el que la investigación está enfocada en los distritos de Lima Norte es debido a que se ha demostrado su continuo crecimiento durante los últimos años, pero este crecimiento se ha dado de forma desordenada y con fuertes limitaciones debido a la falta de acceso al sistema financiero formal y educación. Para el análisis de este estudio se realizó una investigación cuantitativa y causal a una muestra de 385 residentes de Lima Norte. Asimismo, con el objetivo de comprobar las hipótesis planteadas, se aplicó el cuestionario de Adopción y Uso del Dinero Móvil, la Confianza y la Inclusión Financiera para las variables dinero móvil e inclusión financiera. Además, para el objetivo principal y los objetivos secundarios, se analizaron los datos obtenidos a través de una regresión lineal. Los resultados demostraron que el dinero móvil impacta significativamente en la inclusión financiera. Los hallazgos de esta investigación son relevantes y representan un gran aporte para las empresas e instituciones financieras, ya que brinda conocimiento adicional que puede ser utilizado para incrementar el desarrollo de la inclusión financiera en Lima Norte, y como consecuencia replicar el estudio en otras ciudades del país.
Residencia colaborativa con Centro de Atención para el Adulto Mayor
Authors:   , Mosqueira Aguilar Paula Isabel
Published: September 2023

El tema elegido para la investigación es de una Residencia Colaborativa con Centro de Atención para el Adulto Mayor o parejas de adultos mayores que viven solos. En esta propuesta el adulto mayor cuenta además con un centro de atención y espacios para actividades colectivas donde podrán vivir con familias o amigos del mismo rango de edad. Se busca diseñar espacios urbanos y arquitectónicos que puedan ser disfrutados por el usuario en esta etapa de su vida. La soledad es uno de los problemas sociales que afectan al ser humano y en este caso, es importante ya que está comprobado que las personas más afectadas con este problema son los adultos mayores. Existen soluciones arquitectónicas para resolver este problema y las dos más importantes son la Teoría de la Geronto Arquitectura y la Teoría de los Espacios Intermedios, que promueven soluciones espaciales de encuentro y de socialización. La ubicación propuesta para el proyecto es el distrito de San Juan de Lurigancho, donde se encuentra la segunda mayor población de Adulto Mayor que vive solo en Lima Metropolitana (INEI, Adultos mayores de 70 y mas años de edad que viven solos, 2019). Esta ubicación es importante debido a que en la periferia no se ha trabajado el tema de la accesibilidad residencial y urbana para el Adulto Mayor, considerando que esta parte de la ciudad comenzó como una invasión, como es el caso de muchos distritos de la periferia en Lima Metropolitana.
Las infracciones y sanciones tributarias y su impacto en la continuidad de las MYPES del sector textil del distrito de la Victoria, 2019
Authors:   , Quispe Chalco Zahida Mercedes , Perez Gonzales Cristian Ray
Published: September 2023

El presente trabajo de investigación analiza a profundidad, las Infracciones y Sanciones tributarias y su impacto negativo en la continuidad de las MYPES del sector Textil en el año 2019. En el primer capítulo se realiza un análisis de los diversos trabajos de investigación desarrollados en el Perú y en otros países, relacionados a nuestro tema, también detallamos de manera breve la estructura actual de nuestro Sistema tributario peruano, hacemos un análisis de la complejidad del mismo, como de los principios involucrados en el procedimiento sancionador. Continuamos nuestra investigación, recogiendo en parte las infracciones y sanciones contempladas en el Libro cuarto del Código Tributario, así también, del régimen de gradualidad y los regímenes tributarios. Por otro lado, se explica la importancia de las MYPES en nuestra economía, como se constituyen y como están estructuradas. En el segundo capítulo, desarrollamos nuestro plan de investigación, iniciando con la descripción de la problemática que enfrentan las MYPES ante la complejidad de nuestro sistema tributario, con especial énfasis, en la tipificación de infracciones y la determinación de sanciones. Luego, tenemos la formulación de la problemática, objetivos e hipótesis, las mismas que serán la base para nuestros siguientes capítulos. En el capítulo tercero, definimos nuestra población través del uso de información pública de SUNAT, como la determinación de nuestra muestra, aplicando parámetros delimitantes. En el capítulo cuarto, procedemos con el desarrollo de la entrevista y la aplicación de encuestas a las MYPES del sector textil. Finalmente, en el capítulo cinco, analizamos los resultados obtenidos y validamos nuestras hipótesis.
La transformación digital y su impacto en la productividad de los millennials en el sector banca, Lima Metropolitana, período 2018-2020
Authors:   , Espinoza Silva Fiorella Jhadyra , Valdiviezo Zapata Jennifer Oleana
Published: September 2023

La presente investigación busca determinar el impacto que tiene la Transformación digital en la productividad de los millennials en el sector banca, Lima Metropolitana, período del 2018 al 2021. El diseño de la investigación es de tipo no experimental y transversal, con un enfoque cuantitativo. La técnica de muestreo aleatorio para población desconocida fue mediante 385 encuestados millennials que laboren en el sector banca de los 16 bancos a nivel de Lima Metropolitana. El resultado en las pruebas estadísticas no paramétricas del coeficiente de correlación Rho de Spearman (Valor = 0,809), concluye en que se tiene una correlación positiva muy fuerte entre ambas variables del presente estudio, la transformación digital y la productividad de los millennials.
Centro de Investigación Ambiental de Ecosistemas de Montañas y Glaciares en el poblado de Utcuyacu, distrito de Cátac en el departamento de Áncash
Authors:   , Veramendi Huanca Katia Valentina
Published: September 2023

El presente trabajo tiene como objetivo determinar las estrategias de diseño necesarias para la elaboración del proyecto de un centro de investigación ambiental de montañas y glaciares (CIAM) ubicado en Áncash, aplicando la sostenibilidad como énfasis. Teniendo como base la detección de un déficit cualitativo-cuantitativo de esta tipología a nivel nacional, se expone la relevancia del proyecto y su importancia para la región. Se realiza una investigación documental respecto a la teoría e historia del énfasis y de la tipología; la programación arquitectónica; la determinación del terreno y el expediente paisajístico y/o urbano de la sede regional El objetivo del Centro de Investigación es brindar de espacios de calidad, acordes a la tecnología en vanguardia a los diversos investigadores, especialistas y tesistas ambientales, así como ofrecerles espacios de alojamiento, alimentación y esparcimiento para una experiencia más completa y un mejor rendimiento. Finalmente, el entorno natural en el que se ubica el proyecto, así como las condiciones climáticas particulares de la zona condicionan la forma, distribución y diseño del proyecto.
The Theistic God Exists
Authors: Geisler Norman L.
Published: September 2023

This article argues that among the various arguments in favor of the existence of God, they all show that there is only one God, not many. It also argues that this God must be infinite, for He is beyond the finite world that He created. Furthermore, this God must be personal because He is intelligent and moral, being the Intelligent Designer and Lawgiver of the Moral Law. The present article concludes that this God is a spiritual and supernatural Being, as He is beyond the physical and natural world. He, too, can work miracles because He has already performed the greatest miracle of all – He created the world. Thus, we realize that the evidence points to the existence of a God, according to the theistic worldview – an infinite, intelligent, perfect, personal, and supernatural Being.
Criação, Evolução e Hermenêutica: Tendências Recentes no Adventismo
Authors: Zukowski Jean , Cota Mól Luan Alves
Published: September 2023

Resumo: Os adventistas do sétimo dia, desde os seus primórdios, se consideram como um movimento religioso que baseia suas crenças na Bíblia e defende a criação histórica em seis dias literais. Recentemente, propostas que confrontam essa crença têm surgido no meio adventista causando certa reflexão acerca de assuntos até então não discutidos. Entretanto, como esse debate envolve o antigo conflito entre teologia e ciência, é necessário reconhecer que geralmente as discussões se resumem a conflitos entre diferentes interpretações e percepções, sendo que pouca atenção é dada aos pressupostos filosóficos de cada modelo.
Objetivo: Identificar as pressuposições hermenêuticas mais abrangentes que influenciam as principais propostas acerca do debate entre criação e evolução no adventismo.
Metodologia: Através de um levantamento bibliográfico dos escritos de Desmond Ford, Fritz Guy e Roy Graf, este artigo destaca, sem exaurir o tema, os principais proponentes de três diferentes modelos, denominados respectivamente nesta pesquisa de: progressivo (Ford), moderno (Guy) e histórico (Graf).
Resultados: As diferenças doutrinárias dentro do adventismo são condicionadas por bases filosóficas (ontológicas) profundas, sendo que uma análise hermenêutica (e não meramente doutrinária) do debate entre criação e evolução revelam os diferentes paradigmas que atuam como chaves de interpretação para Ford, Guy e Graf, sendo que o último modelo parece se adequar mais com toda a informação fornecida pelas Escrituras e com o sistema filosófico adventista.
Conclusão: Realmente, diferentes bases filosóficas e pressupostos moldam a cosmovisão de tal forma que é possível perceber diferentes interpretações do texto bíblico mesmo dentro de um único movimento religioso. Isso se deve à influência de diferentes fontes de teologia além da Bíblia no processo. Também se percebe a necessidade de, em futuras pesquisas sobre as crenças adventistas e diferentes propostas, sempre reconhecer a necessidade de ir além do debate doutrinário e exegético, buscando perceber os diferentes paradigmas de cada intérprete e suas implicações na formulação teológica.
Mitochondrial DNA: From Forensic Genetics to the Origins of Humanity
Authors: Jorge De Souza Tiago Alves
Published: September 2023

Mitochondria are cellular organelles that provide cellular energy. Along with chloroplasts of plant cells, mitochondria are the only organelles that have genetic material. These peculiarities make mitochondrial DNA (DNA) one of the main research topics in the field of Cytology and Genetics. Interest shared by Criminalistics, which uses mDNA analysis for forensic identification of DNA traces in which nuclear DNA analysis is not possible. In addition to being used in forensic investigation, mtDNA analysis has also been widely used in paleoanthropological investigation through the elaboration of human phylogenies, which retroact to only one female ancestor, known as mitochondrial Eve. In this context, this manuscript aims to address the relevance of this organelle in the field of Criminalistics and the Sciences of Origins, presenting the scientific, philosophical and theological implications arising from the in-depth analysis of this cellular structure.
O Conceito de Ciência em Ellen G. White: A Busca pela Epistemologia Cristã da Verdade
Authors: Lutz Eduardo , Lütz Maria da Graça F.
Published: September 2023

A epistemologia cristã da ciência, sob a perspectiva de Ellen G. White, emerge como uma investigação crucial no contexto contemporâneo. Neste estudo, exploramos a abordagem de White, que distingue com clareza o genuíno do enganoso, alertando para os perigos da pseudociência e enfatizando a responsabilidade intrínseca de adotar somente o conhecimento verdadeiro. A problemática reside na influência crescente de interpretações incorretas da ciência na sociedade. Ao analisar as obras de White, revela-se uma ênfase persistente no discernimento rigoroso e no compromisso com a verdadeira ciência e a importância de buscar-se um contexto integral em sua formulação. Esse achado evidencia a relevância contínua de sua epistemologia para orientar a busca e aplicação do conhecimento científico, mitigando a disseminação de informações distorcidas. Conclui-se que a abordagem epistemológica de Ellen G. White oferece orientação inestimável na preservação da integridade científica e no cumprimento ético de nossa busca pelo saber.
Debates sobre o termo “Imagem-Semelhança” em Gênesis 1:26-27
Authors: Marski Héber Stabenow
Published: September 2023

Este artigo estuda o significado da expressão “imagem e semelhança de Deus”, usada no texto massorético, em Gênesis 1:26 e 27, para descrever a criação da humanidade. Através da visão antropológica bíblica, este artigo visa trazer consciência sobre o propósito de nossa existência. Será usado o método canônico-teológico, que possui quatro corolários: (1) sola Scriptura; (2) uma visão elevada da revelação-inspiração do cânon bíblico; (3) a dupla autoria (divina e humana) do texto canônico; e (4) os procedimentos histórico-gramaticais da exegese. O artigo tem início com um olhar através das várias interpretações da “imagem de Deus” na história, não sendo normativa, mas sugestiva. Em seguida, apresenta uma exegese de Gênesis 1:26 e 27, criticando o livro Dignity and destiny, de John F. Kilner, por ser atualmente o livro com o estudo mais extenso sobre o tema proposto. Para concluir, o trabalho recapitula e sugere a aplicação do estudo proposto como uma visão de mundo para nossa relação teológica, sociológica e ecológica. A visão de mundo que existe em nós mesmos estipula como vamos pensar e agir. Temas como socialismo, feminismo, racismo, diferenças sexuais, infanticídio, ecologismo, veganismo e até mesmo ordenação ao ministério pastoral devem ser lidos e discutidos através de uma perspectiva “humana”.
Headdress or Hairstyle? A Study of 1 Corinthians 11 and the Use of the Veil in Worship
Authors: Chadwick Christie Goulart
Published: September 2023

This article investigates whether Paul is recommending a veil for women in the context of worship, or whether he is discussing appropriate hairstyles for them. A closer look at the passage of 1 Corinthians 11:4–16 shows first of all that Paul is not discussing only women, but the appropriate attire for both men and women in light of what is proper and expected in the Greco-Roman society of his time. The absence of a word for “veil” in the original text points to the possibility of a discussion of hairstyles and not apparel for the head. Archaeological and textual evidence from this period supports this interpretation.
Comparative analysis of social practices in drug abuse prevention: Russian and international experience
Authors: Larina Elena
Published: September 2023

The increasing mortality rate due to drug abuse, including among minors, the rising number of registered individuals with narcotic dependency syndrome, and contemporary characteristics of drug use underscore the social need for analysing drug abuse prevention practices in Russia and other countries. The article presents the results of a review of specialised statistical data and information sources, examining both liberalrestrictive and repressive anti-drug preventive measures. An analysis of current prevention strategies in foreign countries is conducted, including the USA, European countries, China, Japan, and South Korea, along with an examination of anti-drug preventive measures in Russia. The study reveals the greater effectiveness of prevention programmes using a liberal-restrictive approach, which focus on developing protective social skills, stress coping mechanisms, promoting positive interpersonal interactions, and fostering healthy intra-family relationships, in comparison to the repressive approach. The social practices of the latter are based on stricter penalties and intimidation, leading to increased covert drug use, heightened fears of seeking specialised help, exacerbated harmful consequences for users’ health, and a lack of reliable statistical data. The conclusion is drawn that to enhance the effectiveness of drug abuse prevention in Russia, it is advisable to critically evaluate and utilise the experience of countries that emphasise a restrictive approach. The focus should shift from intimidating and harshly punishing drug users to developing positive social skills and creating differentiated support and educational programmes for various population groups.
Artificial Intelligence and algorithmic solutions in the social sphere: youth attitudes
Authors: Nazarov Mikhail
Published: September 2023

Over the past decade, the diffusion of digital innovations among the youth has been advancing at an accelerated pace. The article presents an analysis of the youth’s attitude towards the idea of using social ratings as one of the applications of artificial intelligence (AI) and algorithmic management in the social sphere. The empirical focus of the analysis was on representatives of student youth in three Russian cities - Moscow, Belgorod, and Kyzyl. More than half of the respondents in all regions indicated that the influence of AI technologies on people’s lives would have both positive and negative consequences. The analysis of a model situation - the possibility of widespread use of social ratings - reveals that about one-third of the respondents in all regions supported this idea. In the capital city, the majority of respondents did not support the idea of implementing algorithms for social ratings, while in other regions, the majority of those surveyed were undecided about assessing this issue. There is an increasing level of support and perceptions of fair evaluations of algorithms for social ratings as respondents move away from the capital city. Apparently, the overall digital advancement of the Moscow region is accompanied by an increase in perceptions of the ambiguous social consequences of using AI and algorithmic solutions, leading respondents to be more cautious in assessing the prospects of these technologies. The results of multivariate statistical analysis indicate that the differentiation of support/non-support for the idea of widespread use of social ratings is related to general attitudes towards new technologies, digital media consumption habits, value orientations, and specific characteristics of social demographics. The ambivalent assessment of the prospects of implementing social ratings and the perception of a significant portion of respondents towards algorithmic solutions as unjust highlight the need for balanced management decisions that prioritise human development and the humanitarian potential of society.
Dynamic Modes Simulation of Synchronous Motor Vector Control Electric Drive
Authors: Pugachev Aleksandr , Chuprina Nikolay
Published: September 2023

Purpose: The purpose of the work is a comparative assessment of dynamic processes in electric drives with a vector control system for permanent magnets synchronous motors and various methods of stator voltage modulation. To achieve this purpose, a mathematical description of a synchronous motor in a rotating dq coordinate system is given, and a mathematical model of a vector control system is developed. The model of the vector control system takes into account the decoupling of stator current control loops and proposes two options for generating a current reference along the d-axis, ensuring the efficiency of energy conversion processes at rotation speeds below the nominal value, depending on the design of the motor rotor. Algorithms for scalar pulse-width and space-vector modulation of motor stator voltage for a frequency converter with a two-level autonomous voltage inverter are presented. Methods: When developing mathematical models and algorithms, methods from the theory of electric drive and the theory of automatic control have been used. The developed mathematical models and algorithms are implemented in the Matlab Simulink software package. Results: The results of modeling dynamic processes in electric drives (mechanical characteristics, stator currents, stator current total harmonic distortion) are presented, which have shown the performance of the developed models and algorithms. Practical significance: The choice of modulation type does not affect the mechanical characteristics of the electric drive, but does affect the harmonic composition of the stator current. The greatest effect from the use of space-vector modulation algorithms is manifested at reduced values of the frequency of the stator current and partial load torque on the rotor shaft.
Development of Russia’s Logistics Transport System Under Sanctions
Authors: Pokrovskaya Oksana
Published: September 2023

Purpose: To conduct a review critical analysis of the current state of the domestic logistics transport system of Russia under sanctions as of August 2023 using statistical data and visualization of their dynamics. Methods: Methods of statistical analysis, logistics, systems theory, visualization, system approach, statistical and analytical data from open sources on the Internet have been used. Results: It is shown that the sanctions policy transforms the approach to the management of transportation processes when logistics chains are broken. The analysis of data on volumes and directions of railway transportation in Russia is carried out, trends, prospects and bottlenecks in the work of logistics transport systems are noted. Practical significance: The impact of anti-Russian Western sanctions on the structure and organization of the railway transportation process is assessed. Conclusions are formulated, among which it is indicated that the sustainable development of domestic logistics transport systems is a guarantee of uninterrupted and seamless provision of commodity exchange processes in the country.
Developing a Methodology for the Redistribution of Car Traffic (on the Example of the North-Western Polygon)
Authors: Plenkin Sergey , Novichihin Alexey
Published: September 2023

Purpose: To increase economic efficiency of the process of finding and moving loaded and empty cars on the basis of improving the dynamic model of loading the infrastructure of JSC “Russian Railways” during the implementation of the process of approving applications for cargo transportation and notification requests for the transportation of empty wagons. Methods: Systematic approach and the theory of algorithms have been used to find out the reasons for the accumulation of cars on railways, an analysis has been made of the current distribution of car traffic in the North-Western Polygon to identify systemic patterns that encourage an increase in economic costs. Results: A method of stage-by-stage progress of car traffic has been developed, which allows to synchronize the capabilities and needs of participants of the transport services market in order to obtain a positive economic effect; the conditions for the uniform loading of infrastructure elements are determined, which make it possible to exclude overloading of critically important sections. Practical significance: The method allows us to balance the capacity of the infrastructure and the processing capacity of the consignee, which increases the economic efficiency of the transportation process. Consignees will have access to a tool that allows them to influence the progress of goods to their address, and the carrier will reduce operating costs by eliminating the occupation of infrastructure at the approaches to destination stations.
Procedure for determination of minimum permissible rim thickness of solid-rolled The Method of Determining the Minimum Permissible Rim Thickness of Solid-Rolled Wheels of Freight Cars in Operation
Authors: Vorob'ev Aleksandr , Fedorov Igor' , Konogray Ol'ga , Metlyakova Sof'ya , Migulin Nikita
Published: September 2023

Purpose: Determination of the minimum allowable thickness of the rim of solid-rolled wheels of freight cars depending on the design and axial load. Methods: Methods of elasticity theory, methods of numerical solution of partial differential equations (finite element method) are used. Results: The minimum allowable thicknesses of the rims of solid-rolled wheels of freight cars have been determined, as well as the values of fatigue resistance factors for wheels manufactured according to drawing 13.45.1043-01A, 13.45.1011-143, 13.45.1399-207 with a rim thickness of 30 to 16 mm and various axial load. The calculations showed that for the wheels manufactured according to drawing 13.45.1043-01A, 13.45.1399-207, the minimum permissible rim thickness can be reduced to 16 mm. Practical significance: The dependence of the fatigue resistance coefficient on the rim thickness and axial load with an accuracy of up to 15% is obtained, as well as certain minimum permissible thicknesses of the rims of solid-rolled wheels will increase their service life.
Endoscopic Ear Surgery : 7 Years of Single Center Experience
Authors: KAYA Ercan , İNCESU Armağan , PINARBAŞLI Mehmet Özgür , KAYA Furkan
Published: September 2023

Bu çalışmanın amacı, kliniğimizin endoskopik kulak cerrahisi deneyimlerini paylaşmak ve sonrasında daha detaylı çalışmalar için kılavuz oluşturmaktır. Araştırmada retrospektif olarak kliniğimizde 2015-2022 yılları arasında; endoskopik veya mikroskopla kombine olarak opere olan bireylerin verileri, hastane veri tabanından toplanmıştır. Araştırmaya kliniğimizde endoskopik veya mikroskopla kombine yaklaşımla kulak operasyonu olmuş 70 hastanın verileri dahil edilmiştir. Temelde yapılan cerrahinin niteliğine göre hastalar dört gruba ayrılmıştır. Tip-1 timpanoplasti olan gruptaki 26 vaka ortalama 16,3 ay takip edilmiştir. Eksplorasyon ve işitme rekonstrüksiyonu yapılan gruptaki 9 vakanın takip ortalama süresi 13,4 aydır. Kolesteatom nedeniyle opere edilen 18 kişilik vaka grubu ise ortalama 17,7 ay takip edilmiştir. Stapedetomi yapılan 17 kişilik vaka grubu ise ortalama 14,9 ay takip edilmiş olup hava ve kemik yolu arasındaki gapte ortalama 16,7 desibellik kazanç sağlanmıştır. Endoskopinin KBB pratiğinde giderek yaygınlaşması ve otoloji alanındaki kullanımı düşünüldüğünde, orta kulağa sınırlı patolojilerde geleneksel mikroskobik yaklaşıma göre avantajlarının ileri çalışmalarla desteklemesi gerektiği kanaatindeyiz.
Examining application-specific resiliency implementations in UAV swarm scenarios
Authors: Phadke Abhishek , Medrano F. Antonio
Published: September 2023

The number of real-world scenarios where the use of an unmanned aerial vehicle (UAV) swarm is beneficial has greatly increased in recent years. From precision agriculture to forest fire monitoring, post-disaster search and rescue applications, to military use, the applications are widespread. While it is a perceived requirement that all UAV swarms be inherently resilient, in reality, it is often not so. The incorporation of resilient mechanisms depends on an application usage scenario. This study examines a comprehensive range of application scenarios for UAV swarms to bring forward the multitude of components that work together to provide a measure of resilience to the overall swarm. A three-category scheme is used to classify swarm applications. While systemic resilience is an interconnected concept, most real-world applications of UAV swarm research focus on making certain components resilient to disturbances. A broad categorization of UAV swarm applications, categorized by recognized components and modules, is presented, and prevalent approaches for novel resilience mechanisms in each category are discussed.
Galectin-3 as a Prognostic Biomarker in Patients with First Acute Myocardial Infarction Without Heart Failure
Authors: Vucic Rada M. , Andrejic Olivera M. , Stokanovic Dragana , Stoimenov Tatjana Jevtovic , McClements Lana , Nikolic Valentina N. , Sreckovic Miodrag , Veselinovic Mirjana , Aleksandric Srdjan , Popadic Viseslav , Zdravkovic Marija , Pavlović Milan
Published: September 2023

Background: Galectin-3 (Gal-3) is a biomarker involved in a wide range of diseases including cardiac remodeling following acute myocardial infarction (AMI). Identification of prognostic markers in patients with AMI can guide strategies towards improved survival and the quality of life. Methods: Our study included 59 patients with AMI and preserved ejection fraction. We determined the Gal-3 plasma concentration within 24 hours of chest pain onset from aortic root, femoral/radial artery, coronary sinus and cubital vein. Major adverse cardiovascular events (MACE) were evaluated at six months follow-up. Results: MACE at six months post-AMI was recorded in 20 patients (34%). The Gal-3 plasma concentration from aortic root and the femoral/radial artery were independent predictors of MACE at six months follow-up after the first AMI (OR 1.228; 95%CI: 1.011-1.491; p=0.038; OR 3.438; 95%CI: 1.275-9.265; p=0.015). ROC analysis identifies the Gal-3 plasma concentration from aortic root as a better predictor of MACE or death (cut-off >10.86 ng/ml; AUC 0.858; 95%CI: 0.744-0.973; p<0.001) than Gal-3 plasma concentration from femoral/radial artery (cut-off >10.18 ng/ml; AUC 0.742; 95%CI: 0.596-0.888; p=0.006). Conclusion: The Gal-3 plasma concentration in patients with AMI determined during coronary angiography, especially from the aortic root, within 24 hours after chest pain onset is a valuable biomarker of prognosis at six months follow-up.
O-GlcNAcylation: The Sweet Side of Epigenetics
Authors: Dupas Thomas , Lauzier Benjamin , McGraw Serge
Published: September 2023

Histones display a wide variety of post-translational modifications, including acetylation, methylation, and phosphorylation. These epigenetic modifications can influence chromatin structure and function without altering the DNA sequence. Histones can also undergo post-translational O-GlcNAcylation, a rather understudied modification that plays critical roles in almost all biological processes and is added and removed by O-linked N-acetylglucosamine transferase and O-GlcNAcase, respectively. This review provides a current overview of our knowledge of how O-GlcNAcylation impacts the histone code both directly and by regulating other chromatin modifying enzymes. This highlights the pivotal emerging role of O-GlcNAcylation as an essential epigenetic marker.
Insulin Resistance Develops Due to an Imbalance in the Synthesis of Cyclic AMP and the Natural Cyclic AMP Antagonist Prostaglandyl-Inositol Cyclic Phosphate (Cyclic PIP)
Authors: Wasner Heinrich K
Published: September 2023

Dear Ladies and Gentlemen,

I thank you for suggesting to submit the manuscript with the title

“Insulin resistance develops due to an imbalance in the synthesis of cyclic AMP and the natural cyclic AMP antagonist prostaglandylinositol cyclic phosphate (cyclic PIP)”

to the Editorial Board of the MDPI journal Stresses, and I ask for consideration to publish it in the journal Stresses. It was previously submitted to the MDPI journal Int. J. Mol. Sci. (IJMS-195 6513), but it was found that 1) it would not fit within the scope of this special edition and 2) it would primarily deal with cyclic PIP and would have not enough literature citation on the topic insulin resistance.

The present version of the manuscript is improved, but the content is the same. The goal of this review is not to write again a summary on nearly all reports on insulin resistance as this was done by Dr. Petersen and Dr. Shulman, whose review has 961 literature citations. The present manuscript compiles what is known on cyclic PIP in relation to insulin resistance and the reason of writing this manuscript was that the discovered facts on cyclic PIP synthesis allow to suggest how insulin resistance most likely starts. Hitherto, reports on insulin resistance did not come close to this question. I am convinced that the manuscript makes an essential contribution to the question what causes the development of insulin resistance, and I have to say that stress overload is one of the reasons.

Unfortunately, I have to mention a topic, about which I do not like to talk. Years ago, research groups postulated with rigor that the mediator of insulin action would be a peptide and then they suggested various, extracellularly synthesized glycans as mediators. They caused confusions and a high degree of disbelief in the matter of mediators of insulin action. In my review on cyclic PIP in IUBMB Life from 2020, I wrote in the introduction that cyclic PIP should not be confused with these mediators. But I cannot write this in the introduction of every report. I am keeping fingers crossed so that the editor in charge will find fair and openminded reviewers.

Last not least I confirm that neither the manuscript nor any part of its content is currently under consideration or published in another journal.

Kind regards,
Henrich Wasner, PhD,

BioReg Biopharm, TiLab;
University of Illinois at Chicago;
2242 West Harrison St., Ste. 201,
Chicago, Il 60612; USA
TFR: Texture Defect Detection with Fourier Transform Using Normal Reconstructed Template of Simple Autoencoder
Authors: Si Jongwook , Kim Sungyoung
Published: September 2023

Texture is essential information for image representation, capturing patterns, and structures. Consequently, texture plays a crucial role in the manufacturing industry and has been extensively studied in the fields of computer vision and pattern recognition. However, real-world textures are susceptible to defects, which can degrade the image quality and cause various issues. Therefore, there is a need for accurate and effective methods to detect texture defects. In this study, a simple autoencoder and Fourier transform were employed for texture defect detection. The proposed method combines Fourier transform analysis with the reconstructed template obtained from the simple autoencoder. Fourier transform is a powerful tool for analyzing the frequency domain of images and signals. Moreover, analyzing the frequency domain enables effective defect detection because texture defects often exhibit characteristic changes in specific frequency ranges. The proposed method demonstrates effectiveness and accuracy in detecting texture defects. Experimental results are presented to evaluate its performance and compare it with those of existing approaches.
Reducing Carbon Footprint with Precipitated Calcium Carbonate (PCC) in Geotechnical Applications
Authors: Phuyal Kabiraj , Sharma Ujwal , Mahar James , Mondal Kunal , Mashal Mustafa
Published: September 2023

This study aims to investigate utilizing Precipitated Calcium Carbonate (PCC), a by-product of sugar beet, as a soil stabilizer for addressing settlement issues beneath pavements. Various tests were conducted to assess the engineering properties of PCC-stabilized subgrades using PCC obtained from Amalgamated Sugar Cooperation in Twin Falls, Idaho. Local loess samples, like those found beneath pavements, were collected for testing purposes. Initial tests involved evaluating the unconfined compressive strength of compacted loess samples, followed by tests on samples mixed with different weight percentages of PCC.

The results revealed a significant average increase of 10% to 28% in the strength of loess samples stabilized with 5% PCC compared to the strength of the native soil. The chemical composition and microstructure of PCC were further analyzed through X-ray Diffraction (XRD), Energy Dispersive X-ray Spectrometer (EDX), and Scanning Electron Microscopy (SEM) Tests conducted at the Idaho National Laboratory (INL). XRD analysis indicates the presence of calcium carbonate and silica. EDX analysis unveiled a carbon content of 9% by weight in PCC, which could contribute to the carbon footprint when it breaks down. Additionally, SEM images displayed an irregular microstructure and particle shape of PCC. Furthermore, the inclusion of PCC improved the resistance of loess to saturation collapse.
miR125-Centered ceRNETs in Breast Cancer. Clinical, Molecular and Ethical Aspects in Personalized Medicine
Authors: Piergentili Roberto , Gullo Giuseppe , Cucinella Gaspare , Lopez Alessandra , Napoletano Gabriele , Marinelli Enrico , Zaami Simona
Published: September 2023

According to the International Agency for Research on Cancer (IARC) of the World Health Organization (data of year 2020), Breast Cancer (BC) is one of the most common cancer types worldwide, with large geographical variations occurring between countries and world regions and highest incidence rates in countries that have undergone economic transition. The risk factors for BC include women ageing, genetic mutations, reproductive history, dense breast tissues, personal history of BC or specific non-cancerous breast diseases, family history of breast or ovarian cancer, previous treatment using radiation therapy, and exposure to hormone-like drugs such as diethylstilbestrol (DES). Additional risk factors include being overweight or having obesity after menopause, and taking hormones. MicroRNAs (miRNAs or miRs) are small non-coding RNA molecules that have an essential role in gene expression and are significantly linked to the tumor development and angiogenesis process in different types of cancer, including BC. In the last years, the knowledge about miRNAs role in BC has significantly improved, and complex interactions among coding and non-coding RNA has been elucidated. In this context, an increasing number of papers had been published regarding the role of miR-125 in BC. In this review, we summarize the state-of-the-art about this research topic in addition to elaborating on the need to set novel ethical and legal standards for the governance of such innovations in healthcare.
Bilinç Problemine Sentezci Bir Yaklaşım: Nörofenomenoloji
Authors: DOĞAN Mehtap
Published: September 2023

Zihin felsefesinin çetin problemlerinden olan bilince yönelik olarak bilincin öznel karakterinin bilimsel olarak açıklanamaz olduğunu kabul eden düalist ve idealist yaklaşımlar ile bilincin fiziksel olana indirgenebilir olduğunu savunan fizikalizm arasında orta yolu işaret eden nadir bir bakış açısı nörofenomenolojidir. Nörofenomenoloji, deneyime yönelik öznel bildirimleri, nörobilimsel yöntemleri kullanarak analiz etmeyi hedeflerken; öznel-nesnel karşıtlığını bedenlenmiş eylem görüşüyle aşmaya çalışan enaktif (varlık-oluşturucu) yaklaşımı temele almaktadır. Felsefi fenomenolojide köklerini bulabileceğimiz bedenlenmiş biliş yaklaşımından hareketle, deneyim ve dış dünya arasındaki süreklilik ilişkisini betimleyen nörofenomenolojik yaklaşım, çeşitli meditasyon teknikleri ile deneyimlerini dışsal etkilerden arındırabilen deneklerden elde edilen nöral görüntüleme verilerini kullanarak öznel deneyimin doğasını soruşturmayı yöntem olarak benimsemektedir. Nörofenomenolojinin amacı fenomenolojik deneyim üzerine sistematik ve kurallara dayalı araştırmalar yoluyla daha zengin birinci şahıs verileri elde etmek ve bu birinci şahıs verilerini nöral süreçler hakkında yeni üçüncü şahıs verilerini ortaya çıkarmak için kullanmaktır. Bu çalışmada, ilk olarak nörofenomenolojinin felsefi temelleri üzerine bir inceleme yapılmakta, ardından nörofenomenolojik yaklaşımın hedefleri ve sunduğu yöntem önerisi değerlendirilmekte ve son olarak, bu yaklaşımın bilinç problemine yönelik geçerli bir çözüm önerisi olarak ele alınıp alınamayacağı tartışılmaktadır.
Microseira wollei (M. wollei) blooms in freshwater ecosystems in Lake St. Clair (Michigan, USA)–impacts and possible management approaches
Authors: Butler Afrachanna , Thomas Catherine , Calomeni Alyssa , McQueen Andrew , Slack William
Published: September 2023

The proliferation and shoreline accumulation of the filamentous biphasic cyanobacterium, Microseira wollei (M. wollei) (previously classified as Lyngbya wollei), have become an increasing problem in the Great Lakes, both for aesthetic reasons and its potential to harbor harmful bacteria and pathogens (Vijayavel et al. 2013). Occurrences have been reported and studies have also been conducted in the southeastern US where M. wollei has become a nuisance in recent years and is known to produce toxins (Hudon et al. 2014). Reports of M. wollei proliferations in the eastern US have been identified in the Manitoba lakes (Macbeth 2004), in Lake Erie from Maumee Bay (Bridgeman and Penamon 2010), in Lake St. Clair near Detroit (Vijayavel et al. 2013), and throughout the St Lawrence River (Vis et al. 2008; Lévesque et al. 2012). M. wollei has become a serious nuisance for marinas, public beaches, and lakefront property owners. In addition, M. wollei appears to have the ability to produce a wide range of toxins, but the conditions promoting their production, type, and concentration are poorly known (Hudon et al. 2014). Occurrences of large algal mats matching characteristics of M. wollei have been observed along the northwest shore and nearshore waters of the beach at Lake St. Clair dating back to 2010. To date, a comprehensive study detailing the potential impacts M. wollei has on freshwater ecosystems in the Great Lakes River, particularly Lake St. Clair is lacking. Further, management solutions are not well understood. This technical note (TN) reviews the potential causes of M. wollei blooms and their ecological impacts on aquatic systems and assesses the management options available to eliminate or minimize the impacts of these blooms.
Determinant of Consumer’s Decision to Use Islamic Saving Account in Bank Syariah Indonesia Post Merger in 2021 Period
Authors: Kusumanisita Apriliana Ika , Anugrah Raditya Iqbal , Taufiq Affandi Muchammad
Published: September 2023

Increasing awareness about halal products  in the Islamic finance industry sector can encourage the development of Islamic economy and finance in Indonesia. The financial industry is a pillar of the national economy that is expected to advance the general welfare and global competitiveness, especially in Islamic banking which has contributed to economic growth in Indonesia. Theory of Planned Behaviour (TPB) is used to measure customers decision to keep saving in Bank Syariah Indonesia. The independent variables used in the study were trust, quality of service, religiosity, and Revenue Sharing, while the dependent variables used in the study were customer decisions to keep saving. The sample of this study was 120 respondents from Customers of Bank Syariah Indonesia located throughout Java Island. The results showed that Trust, Quality of Service, and Religiosity had no significant effect on the customer's decision to keep saving in Bank Syariah Indonesia, meanwhile revenue sharing has a significant influence on the decision of customers to keep saving in Bank Syariah Indonesia.
The Influence of Leadership Style on Employee Performance through Readiness For Change Post Acquisition Company
Authors: Fahira Keke Tamara , Yasin Rozaq Muhammad
Published: September 2023

The current period of acquisition strategy is an effective and efficient way to relocate assets in the economy, especially the banking sector. The acquisition brought many changes to the organization. The research aims to answer the influence of post-acquisition Leadership Style on employee performance through Readiness for Change as an intervening variable. This research method uses Partial Least Square (PLS). This study uses a non-probability sampling method to collect data. Primary data is used in this study by distributing 100 sample questionnaires to employees at BRI AGRO bank. The finding is that leadership style has a significant effect on employee performance post-acquisition through readiness for change. The results of the study, can be concluded that in order to improve the performance of employees at Bank BRI AGRO, they can maintain and improve their leadership style. In addition to mediating research variables, Readiness for Change also has a direct influence on employee performance.