bluuebunny/crossref_metadata_2025 huggingface dataset:
TRAUMATISMO CRANIOENCEFÁLICO NO MUNICÍPIO DE FORTALEZA
Authors: Da Silva Josi Andrade , De Souza Adriano Rodrigues , Feitoza Aline Rodrigues , Cavalcante Tatiana De Medeiros Colletti
Published: April 2017

Objetivo: traçar o perfil epidemiológico dos pacientes com diagnóstico de traumatismo cranioencefálico (TCE) atendidos em um hospital de referência em trauma no município de Fortaleza-CE. Metodologia: trata-se de um estudo descritivo, quantitativo e documental com 722 prontuários de vítimas de TCE. Resultados: a pesquisa mostrou maior incidência de casos no gênero masculino, com idades entre 21 e 30 anos, provenientes do interior do estado, cujo maior número de internamentos aconteceram no final de semana. Quanto à evolução dos casos, 84% tiveram alta, enquanto 16% foram a óbito. Conclusão: diante dos resultados obtidos, concluímos que o conhecimento deles se torna uma importante ferramenta de implementação de medidas de intervenção com vistas à prevenção e à redução dessas lesões.Descritores: Traumatismos craniocerebrais, Epidemiologia, Traumatismos encefálicos.TRAUMATIC BRAIN INJURY IN THE MUNICIPALITY OF FORTALEZAObjective: to trace the epidemiological profile of patients with diagnosis of traumatic brain injury (TBI) treated at a referred hospital for trauma in Fortaleza-CE. Methodology: This is a descriptive, quantitative and documentary study with 722 medical records of victims of TBI. Results: Research has shown a higher incidence of cases in males aged 21 to 30 years from the countryside of the state, where the highest number of hospitalizations occurred over the weekend. As for the evolution of the cases, 84% were discharged while 16% died. Conclusion: based on the results obtained, we conclude that their knowledge becomes an important tool for implementing the intervention measures aimed at preventing and reducing these injuries.Descriptors: Craniocerebral trauma, Epidemiology, Brain injury.LA LESIÓN CEREBRAL TRAUMÁTICA EN EL MUNICIPIO DE FORTALEZAObjetivo: trazar el perfil epidemiológico de los pacientes con lesión cerebral traumática (LCT) tratado en un hospital de referencia para el trauma en Fortaleza-CE. Metodología: Se trata de un estudio descriptivo, cuantitativo y documental de 722 historias clínicas de las víctimas de LCT. Resultados: La investigación ha demostrado una mayor incidencia de casos en varones de 21 a 30 años desde el interior del estado, cuyo mayor número de hospitalizaciones ocurrido durante el fin de semana. A medida que la evolución de los casos fueron dados de alta 84% mientras que el 16% murió. Conclusión: los resultados obtenidos, llegamos a la conclusión de que su conocimiento se convierte en una herramienta importante para la aplicación de las medidas de intervención dirigidas a la prevención y la reducción de estas lesiones.Descriptores: Traumatismo craneoencefálico, Epidemiología, Lesión cerebral.
COMPROMETIMENTO DA SEXUALIDADE DE MULHERES COM CÂNCER DE MAMA
Authors: Varela Ana Inêz Severo , Rosa Luciana Martins da , Sebold Natália , Laverde Ana Gabriela , Maçaneiro Amarildo , Erdmann Alacoque Lorenzini
Published: April 2017

Objetivo: identificar os obstáculos relacionados à sexualidade e à vida sexual de mulheres com câncer de mama. Metodologia: pesquisa descritiva, que incluiu dez mulheres submetidas à mastectomia ou quandrantectomia residentes no município de Florianópolis, selecionadas pelo método bola de neve. Dados obtidos por entrevistas semiestruturadas, realizadas entre março e maio de 2014, submetidos à análise de conteúdo e sustentados teoricamente por estudos afins. Resultados: os obstáculos encontrados envolvem o enfrentamento familiar e pessoal comprometidos e a alteração sexual e ginecológica. Conclusão: apesar do avanço científico e tecnológico, permanece a necessidade de cuidado integral e individualizado à mulher, aos companheiros e aos familiares.Descritores: Sexualidade, Neoplasias da mama, Mastectomia, Enfermagem.COMMITMENT TO SEXUALITY OF WOMEN WITH BREAST CANCERObjective: Identify obstacles related to sexuality and sexual life of women with breast cancer. Methodology: descriptive study, which included ten women undergoing mastectomy or quandrantectomia, residents in Florianopolis, selected by snowball method. Data from semistructured interviews, conducted between March and May 2014 and submitted to content analysis and theoretically supported by related studies. Results: The obstacles encountered includes confrontation of family and personal commitment and sexual and gynecological change. Conclusion: Despite the scientific and technological advances remain the need for comprehensive care and individualized to women, to companion and family.Descriptors: Sexuality, Breast neoplasms, Mastectomy, Nursing.COMPROMISO DE LA SEXUALIDAD DE LAS MUJERES CON CÁNCER DE MAMAObjetivo: Identificar los obstáculos relacionados con la sexualidad y la vida sexual de las mujeres con cáncer de mama. Metodología: estudio descriptivo, que incluía diez mujeres sometidas a mastectomía o quandrantectomia, residentes en Florianópolis, seleccionados por el método bola de nieve. Los datos recogidos por entrevistas semi-estructuradas, entre marzo y mayo de 2014, sometido a análisis de contenido y, en teoría apoyada por estudios relacionados. Resultados: Los obstáculos encontrados implican hacer frente familia y la evolución sexual y ginecológica personal y comprometido. Conclusión: A pesar de los avances científicos y tecnológicos continúa la necesidad de una atención integral e individualizada a las mujeres, compañeros y familiares.Descriptores: Sexualidad, Neoplasias de la mama, Mastectomía, Enfermería.
SEGURANÇA DO PACIENTE NA VISÃO DE ENFERMEIROS: UMA QUESTÃO MULTIPROFISSIONAL
Authors: De Araujo Marcos Antonio Nunes , Lunardi Filho Wilson Danilo , Da Silveira Rosemary Silva , Souza Jose Carlos , Barlem Edison Luiz Devos , Teixeira Nanci Da Silva
Published: April 2017

Objetivo: identificar como o enfermeiro percebe a segurança do paciente na instituição de saúde em que atua. Metodologia: estudo descritivo, de corte transversal, realizado entre janeiro e fevereiro de 2016, em Dourados/MS, com 52,58% da população de 310 enfermeiros hospitalares. Aplicou-se questionário sociodemográfico com questões vinculadas à segurança do paciente, cujos dados foram submetidos à análise descritiva. Resultados: parte dos enfermeiros apontou menor segurança quanto aos procedimentos, cuidados e administração de medicamentos. Conclusão: compete à equipe multiprofissional atuar na promoção da segurança do paciente, sendo o enfermeiro o profissional apto a identificar e comunicar riscos iminentes, prevenindo a ocorrência de danos e promovendo saúde na sua integralidade, devido à assistência de enfermagem ocorrer ao longo das 24 horas do dia.Descritores: Segurança do paciente, Gerenciamento de risco, Papel do enfermeiro, Raciocínio clínico.PATIENT SAFETY IN THE PERPECTIVE OF NURSES: A MULTI PROFESSIONAL ISSUEObjective: to highlight how the institutional safety is in the perspective of nurses. Methodology: a cross-sectional descriptive study conducted between January and February 2016, in Dourados City, State of Mato Grosso do Sul, Brazil, with 52.58% of 310 hospital nurses. A sociodemographic questionnaire with questions about “patient safety” was used. A descriptive and statistical analysis was performed. Results: some of the nurses indicated less safety regarding procedures, care and administration of medication. Conclusion: It is the role of multi professional team to promote patient safety. Nurses are capable of identifying and communicating imminent risks, due to their 24 hours assistance, preventing injuries and promoting health in its entirety.Descriptors: Patient Safety, Risks Management, Nurse’s Role, Clinical reasoning.SEGURIDAD DE LOS PACIENTES EN LA PERCEPCIÓN DE ENFERMEROS: UNA CUESTIÓN MULTIPROFESIONALObjetivo: identificar cómo la enfermera percibe la seguridad del paciente en la institución de salud en que actúa. Metodologia: estudio descriptivo de corte trasversal hecho de enero a febrero de 2016, en Dourados/MS, con 52,58% de la población de enfermeros hospitalarias. Se utilizó encuesta sociodemografica respecto la “seguridad del paciente” Se hizo el análisis descriptivo y estadístico. Resultados: parte considerable de los enfermeros indicó menor seguridad cuanto a procedimientos, cuidados y administración medicamentosa. Conclusión: el equipo multiprofesional debe promover la seguridad del paciente, considerando el enfermero como el más apto a identificar y comunicar riesgos inminentes en las 24h de su asistencia, evitando danos e promocionando salud en su integralidad.Descriptores: Seguridad del paciente, Administración de riesgos, Función de los enfermeros, Raciocinio clínico.
Comparison of Meniscal Cell-Mediated and Chondrocyte-Mediated Calcification
Authors: Kiraly Alex J. , Roberts Andrea , Cox Michael , Mauerhan David , Hanley Edward , Sun Yubo
Published: April 2017

Background:

Chondrocytes have been traditionally thought to be responsible for calcium crystal deposits within osteoarthritic knees. Increasing recent experimental evidence suggests that menisci may also play a role. However, the calcifying potential of chondrocytes and meniscal cells derived from same OA patients, and the genes associated with meniscal calcification have never been fully examined.

Objective:

Examine and compare the calcifying potential of articular chondrocytes and meniscal cells derived from same OA patients and identify the calcium crystal type(s) and selected gene expression in OA menisci.

Methods:

Chondrocytes and meniscal cells were isolated from articular cartilage and menisci of OA patients undergoing total knee arthroplasty. Chondrocyte- and meniscal cell-mediated calcification was examined using both monolayer and micromass culture-based assays. Crustal types were examined with histological staining. Levels of Type X Collagen, MMP-13, and ANKH in OA menisci were examined using immunohistochemistry.

Results:

Primary human OA meniscal cells produced calcified deposits at a similar rate compared to OA chondrocytes in-vitro. Histological examinations indicate that both BCP crystals and CPPD crystals are present in the meniscal tissue. Type X collagen, MMP-13, and ANKH were found in human OA menisci and their levels increased with OA severity. In addition, type X collagen was co-localized with calcium crystals.

Conclusion:

These findings suggest that OA meniscal cells have a similar calcifying potential as OA chondrocytes, supporting a pathogenic role of OA menisci in OA.
Concepciones de infancia en el manual de convivencia: una mirada a los derechos y deberes en la escuela
Authors: Alfonso Talero Óscar Emilio , Sánchez Guzmán Luis Eduardo
Published: April 2017

El presente artículo expone una síntesis analítica del proceso desarrollado en la investigación titulada “Concepciones de Infancia: su relación con los derechos y los deberes de los niños y las niñas. Estudio de caso sobre el Manual de Convivencia del Colegio Paulo Freire IED”. Para llevar a cabo la síntesis se expone el problema central de la investigación, los propósitos, el marco teórico, la metodología, los resultados y las conclusiones. En tal medida, se recalca que el estudio centra sus esfuerzos en el análisis del concepto de infancia y su relación con la realidad del espacio contextual del colegio, para así determinar si se coadyuva o no en el desarrollo de los derechos y deberes de los niños.
Emerging zoonosis of a novel avian influenza A (H7N9) Virus. Are we prepared in the neotropics?
Authors: Mattar V Salim , González T Marco
Published: April 2017

Zoonotic diseases represents a 78% of emerging and reemerging diseases, virus has an important proportion in zoonosis. We are not amazing anymore, we frequently see new virus that suddenly appears producing high morbidity and mortality, and all of them have non-specific treatment to try stopping them. The entire recent virus that came to our modern societies, were original from animals.The first human infections with a novel avian influenza A (H7N9) virus were described in China in March 2013 (1-3). The virus was detected in poultry (1-3). Many of the people infected (77%) with H7N9 have been reported to have contact with poultry. While mild illness in human cases has been seen, most patients have had severe respiratory illness and some people have died. No cases of H7N9 outside of China have been reported yet. The new H7N9 virus has not been detected in people or birds in the neotropics (1-3).Human infections with avian influenza occur most commonly after exposure to infected poultry (1-3). Limited person-to-person spread of bird flu is believed to have occurred rarely in the past, most notably with avian influenza A (H5N1). Based on this previous experience with avian influenza A (H5N1), some limited human-to-human spread of this H7N9 virus would not be surprising. Most important, however, is that this transmission not be sustained (1-3).
Factores que afectan la vida útil de vacas doble propósito
Authors: Murcia R Leidys , Martínez G Gonzalo
Published: April 2017

RESUMENObjetivo. Determinar el efecto de factores no genéticos y de grupo racial, sobre la vida útil (VU) de vacas doble propósito. Materiales y métodos. Se utilizó información de 2098 vacas, que incluyó a todas las hembras que ingresaron a servicio y salieron del sistema productivo. La VU se cuantificó como el total de partos al salir del rebaño. Los efectos incluidos en el modelo fueron hacienda (H: AG, VV), año de primer parto (A1P: 1995-2006), época de primer parto (E1P: Enero-marzo, abril-mayo, junio-agosto, septiembre-diciembre) grupo racial (GR: C, 50C50E, ML) y las interacciones HxGR y A1PxGR. Resultados. La media de VU fue de 2.63 partos ± 0.07. Todos los factores tuvieron efectos altamente significativos (p<0.01) sobre VU, menos H. Es interesante resaltar que las interacciones HxGR y A1PxGR fueron altamente significativas (p<0.01) indicando que los grupos raciales se comportan diferente en cada hacienda y en el transcurso de los años. Conclusiones. Los efectos no genéticos y de grupo racial tienen una alta influencia sobre VU.
Estudio anatomopatológico de aislados de Leptospira spp., provenientes de Nicaragua en Mesocricetus auratus como biomodelo
Authors: Rosario F Luis , Arencibia A Daniel , Batista S Niurka , Jirón T Willian , Infante B Juan
Published: April 2017

RESUMENObjetivo. El objetivo de este trabajo fue caracterizar en el biomodelo Mesocricetus auratus la sintomatología y lesiones anatomopatológicas que provocan 5 aislados clínicos de Leptospira spp., provenientes de Nicaragua. Materiales y métodos. Con este fin se inocularon 50 hámster por vía i.p con 1mL del cultivo de cada una de las cepas en fase exponencial teniendo una concentración celular de 7.5 x 106 leptospira/mL (10 animales por cepa), evaluándose signos de la enfermedad, mortalidad durante 14 días, lesiones anatomopatológicas macroscópicas y microscópicas mediante tinción con hematoxilina-eosina y tinción de Warthyn Starryn. Resultados. Todas las cepas presentaron alta mortalidad, mostrando un cuadro tanto clínico, como lesional característico de la infección experimental. Además, causaron la muerte al 100% de los animales entre el tercer y décimo día postinfección. En el estudio anatomopatológico la cepa del serogrupo Ballum y la del serogrupo Pomona produjeron focos de hemorragias específicamente en el riñón y pulmones. De forma similar ocurrió una congestión hepática y renal, mientras que la hemorragia renal fue observada con mayor frecuencia en la cepa del serogrupo Pomona, diferenciándose del resto de las cepas que mostraron esta lesión con menos frecuencia. Conclusiones. Este trabajo permitió una mayor caracterización de estas cepas siendo utilizadas como futuras candidatas vacunales frente a una nueva epidemia de Leptospirosis en Nicaragua.
Afinidades biogeográficas de los galateoideos (Decapoda: Anomura) del Caribe y Pacífico colombiano
Authors: Navas S Gabriel R. , Bermúdez T Adriana , Ángel-Yunda Catalina , Campos Néstor Hernando
Published: April 2017

RESUMENObjetivo. Determinar la distribución y afinidades biogeográficas de los galateoideos de aguas colombianas con base en la literatura y muestras recolectadas durante expediciones realizadas entre 1999 y 2002. Materiales y métodos. Se recolectaron ejemplares en 100 estaciones entre 20 y 550 m de profundidad en el Caribe y Pacífico colombiano. El material recolectado, junto con la información geográfica existente en literatura para las especies conocidas para Colombia se emplearon para realizar mapas de distribución, los cuales se compararon con el “Mapa de ecorregiones marinas del mundo”. Resultados. Se obtuvo la información geográfica para 3247 ejemplares recolectados de 18 especies de los géneros Agononida, Anomoeomunida, Munida, Munidoposis y Pleuroncodes, y se complementó con la obtenida a partir de la literatura para las 40 especies de la superfamilia con presencia conocida en aguas colombianas. Se generaron cinco grupos principales de distribución: especies restringidas al Caribe, al Caribe y Atlántico occidental, Anfiatlánticas, restringidas al Pacífico oriental y Anfiamericanas. Se encontró que el 53 % de las especies recolectadas en el Caribe se presentan también en la provincia Atlántico Norte Cálido-Templado, y para el Océano Pacífico la mayor afinidad se da con la provincia Pacífico Oriental Tropical. Conclusiones. Los galateoideos en aguas colombianas presentan ámbitos geográficos y batimétricos amplios, presentándose simpatría entre algunas especies. Las de aguas someras presentan mayores restricciones que aquellas de distribución en aguas profundas. Los mecanismos de distribución de las especies corresponden con el ciclo de vida de cada una y las corrientes predominantes en las provincias.
Comparison of systemic and intramammary dry cow treatments
Authors: Contreras B G. Andres , Guterbock Walter M. , Muñoz R Juan , Sears Phillip M.
Published: April 2017

ABSTRACTObjective. To compare four different dry cow treatments (DCT) and establish their effectiveness in reducing intramammary infections (IIM). Materials and methods. DCTs included systemic tylosin (12g) alone or accompanied by cefapirine intramammary infusions and or an internal teat sealant. A total number of 278 cows at the end of lactation period were randomly assigned to one of 4 dry cow treatment groups: CESE Group (n=89), intramammary cephapirin and teat sealant. TYCESE Group (n=84), intramammary cephapirin, tylosin 12 g intramuscular and teat sealant. TYSE Group (n=86), 12 g intramuscular tylosin and teat sealant; TY Group (n=76) 12 g intramuscular tylosin only. Milk samples for culture were collected at dry-off and 1 and 2 weeks after calving. Somatic cell counts (SCC) were taken from Dairy Herd Improvement Association (DHI) tests at dry-off, and the first two test days after calving. Results. Bacteria cure rate for Gram-positive intramammary infections (IMI) for TYCESE group was 93.6%, CESE group 78.9%, TYSE group 88.2%, and TY group 78.1%. All four groups showed a decrease in the SCC upon the first and second test after calving. Conclusions. The use of systemic tylosin in combination with intramammary antibiotics increased DCT effectiveness improving the Gram-positive cure rate IMI. Furthermore, systemic tylosin alone plus teat sealant is as effective as cephapirin plus teat sealant when used as DCT.
Determinación y prevalencia de Mycobacterium spp., en tilapia nilótica (Oreochromis niloticus) cultivada en Campeche, México
Authors: Lara-Flores Maurilio , Balan-Zetina Sara , Zapata Ana , Sonda-Santos Karina
Published: April 2017

RESUMENObjetivo. Determinar la presencia y prevalencia de Mycobacterium spp., en granjas de tilapia nilótica (Oreochromis niloticus) en el Municipio de Champotón, Campeche, México. Materiales y métodos. La colecta de organismos se realizó en tres granjas de cultivo de tilapia nilótica del municipio de Champotón, Campeche, México. Los organismos se examinaron externa e internamente y se tomó una muestra de riñón la cual fue sembrada en forma de estría en medios de cultivo: Löwesntein-Jensen, TCBS, KF y en TSA; las placas fueron incubadas a 35°C de 24 a 48 horas, los órganos fueron fijados en formalina tamponada al 10% para ser procesados para histología de rutina para análisis posteriores. Asimismo, muestras de cultivo bacteriológico y de tejido fueron teñidas con la técnica de Ziel-Neelsen con el fin de observar la presencia de bacilos ácido-alcohol resistentes. Resultados. Los resultados obtenidos sugieren que la presencia de Mycobacterium spp., es constante y en alta prevalencia y puede ser un factor que este mermando la rentabilidad del cultivo. Conclusiones. La presencia de Mycobacterium spp., representa un riesgo para el cultivo de tilapia en el municipio de Champotón, por ser una enfermedad muy persistente y difícil de erradicar una vez ocurrido e brote de infección, por lo cual es importante llevar estudios más detallados de la presencia de este género bacteriano, así como, medidas de prevención y dispersión de este patógeno en los cultivos adyacentes.
Parasites and hepatic histopathological lesions in lisa (Mugil incilis) from Totumo mash, North of Colombia
Authors: Olivero V Jesús , Arroyo S Bárbara , Manjarrez P Ganivet
Published: April 2017

ABSTRACTObjective. To assess the levels of parasitism by nematodes and trematodes, as well as the hepatic histopathological alterations present in Mugil incilis (Lisa) from Totumo marsh, North of Colombia. Materials and methods. Between July 2004 and June 2005, 500 fish were collected at Totumo Marsh (75°16’W and 10°44´N), North of Colombia. Morphometric and parasitic parameters were determined for each specimen, and the hepatic histopathological status of the liver was assessed by analyzing liver slides stained with hematoxylin and eosin. Results. Nematode larvae isolated from Mugil incilis corresponded to Contracaecum spp. Parasite prevalence was 60.49%. Parasitic mean abundance and mean intensity were 4.8±1.05 and 7.02±1.49, nematodes per fish, respectively. The correlation between nematode mean abundance and fish length was significant and positive (r=0.525, p<0.0001), but negative for condition factor (r=-0.109, p=0.014). Hepatic histopathological analysis revealed the presence of encapsulated trematode larvae as the main finding. However, the presence of inflammation, granulomas, steatosis and necrosis, were also registered as secondary alterations. Conclusions. Lisas collected at Totumo Marsh are parasitized with nematodes and trematodes. These fish have different histopathological lesions in the liver tissue, being the most important the presence of trematode encapsulated cyst that generate inflammatory reactions, and negatively correlate with morphometric markers of fish health.
Effect of freezing and thawing rates on sperm motility in Bocachico Prochilodus magdalenae (Pisces, Characiformes)
Authors: Martínez José G. , Pardo C Sandra
Published: April 2017

ABSTRACTObjective. To determine the freezing and thawing rates necessary to maintain sperm viability during cryopreservation of Bocachico semen. Materials and methods. Four interactional treatments were implemented between two freezing (rapid and slow) and two thawing (rapid and slow) curves, in a 2x2 factorial as follows: rapid freezing-rapid thawing, rapid freezing-slow thawing, slow freezing-rapid thawing, and slow freezing-slow thawing. After thawing by Sperm Class Analyzer (SCA) curvilinear velocity (VCL) and straight-line (VSL) (μm sec-1) were analyzed; total, rapid, medium, and slow motility, were compared among treatments. Results. The rapid freezing-slow thawing treatment was lethal for all variables of velocity and motility, causing a significant (p<0.01) post-thaw inmotility of 100%. The slow freezing-rapid thawing interaction had a significantly higher effect than the other treatments (p<0.05), particularly on variables such as rapid motility (10.1 ± 1.1%), medium motility (30.16 ± 4.1%), and curvilinear velocity (51.5 ± 4.75 μm sec.-1) also decreased the percentage of sperm with slow motility (41.7 ± 4.45%). Independently of the applied thawing rate, the freezing rate generated the main significant effect on total motility. Conclusions. It is possible to conclude that the interaction effect between freezing and thawing rates is nil (except for slow motility) during cryopreservation process. However, the independent effects of these factors (main effects) on remaining motility variables are positively significant and decisive to the maintenance of these features, especially the freeze factor (when it is slow). This becomes the first successful report of sperm cryopreservation from Bocachico Prochilodus magdalenae in the world and may be used in conservation programs for this endangered species.
Factores que afectan la preñez en vacas Brahman sometidas a inseminación artificial a tiempo fijo
Authors: Correa-Orozco Adriana , Uribe-Velásquez Luis , Pulgarín-Velásquez Erik
Published: April 2017

RESUMENObjetivo. Evaluar la relación entre la condición corporal (CC), la manifestación de estro, las concentraciones plasmáticas de estradiol, el diámetro del folículo mayor y la preñez, en vacas Bos indicus amamantando, sometidas a un protocolo de inseminación artificial a tiempo fijo (IATF). Materiales y métodos. Treinta y ocho vacas Brahman recibieron un dispositivo intravaginal de progesterona + benzoato de estradiol en el día 0; retiro del dispositivo + dinoprost + gonadotropina coriónica equina en el día 9 y la IATF en el día 12. La preñez fue diagnosticada 90 días después de la IATF. Resultados. No hubo efecto de la CC sobre la manifestación de estro, las concentraciones plasmáticas de estradiol o el diámetro del folículo mayor (p>0.05). El diámetro del folículo mayor no influenció las concentraciones plasmáticas de estradiol (p>0.05). El diámetro del folículo mayor y las concentraciones plasmáticas de estradiol no influenciaron la manifestación de estro (p>0.05). La tasa de preñez por IATF no fue afectada (p>0.05) por la CC, la manifestación de estro o las concentraciones plasmáticas de estradiol. Hubo una tendencia (p=0.10) de una relación directa entre el diámetro del folículo mayor y la tasa de preñez por IATF. Conclusiones. La CC, las concentraciones plasmáticas de estradiol y la manifestación de estro no influenciaron la tasa de preñez por IATF en vacas Brahman sometidas a un protocolo de sincronización basado en progesterona. Sin embargo, el diámetro del folículo mayor presentó tendencia al impacto positivo sobre la tasa de preñez por IATF.
Expresión de enzimas relacionadas con el metabolismo de glucocorticoides en tejidos ováricos bovinos
Authors: López C Michael , Amweg Ayelen , Stangaferro Matías , Ortega Hugo
Published: April 2017

RESUMENObjetivo. Identificar la expresión de enzimas relacionadas con el metabolismo de glucocorticoides en tejidos ováricos bovinos. Materiales y métodos. Se obtuvieron muestras de tejidos provenientes de ovarios sanos (n=10) y con Enfermedad Quística Ovárica (COD) (n=10), a las cuales luego de su procesamiento histológico, se las incluyó en parafina. Mediante la técnica de inmunohistoquímica indirecta, se identificaron in situ en folículos primarios, secundarios, terciarios, atrésicos y quistes de las isoformas 1 y 2 de la enzima 11ß-hidroxiesteroide deshidrogenasa (11βHSD) utilizando anticuerpos específicos. Resultados. La expresión de la enzima 11βHSD-1 presentó diferencias significativas únicamente en las células de la granulosa de los diferentes grupos foliculares. La enzima 11βHSD-2 mostró diferencias significativas con respecto a su expresión en las células de la granulosa de los folículos primarios comparada con los folículos secundarios y quísticos. En las células de la teca interna, esta diferencia se observó entre los folículos terciarios y los folículos atrésicos y quísticos. En las células de la teca externa, los folículos terciarios mostraron diferencias significativas en su expresión con respecto a los folículos atrésicos. Conclusiones. Se demostró la presencia de las isoformas tipo I y II de 11βHSD en tejidos ováricos bovinos obtenidos de frigorífico, lo que permite inferir la existencia de un mecanismo endocrino de regulación de la actividad de los glucocorticoides, que podría alterar el patrón normal de desarrollo folicular generando estructuras foliculares anovulatorias y/o quistes foliculares, y al mismo tiempo anestro y otras alteraciones reproductivas en bovinos
Variaciones hematológicas y de presión sanguínea en perros después de una picadura de abejas
Authors: Muñoz G Jorge , Arnes V Verónica , Mieres L Marcelo , Noro Mirela
Published: April 2017

RESUMENObjetivo. El objetivo de este estudio fue determinar los cambios hematológicos y de presión arterial en perros después de una picadura cutánea de abejas. Material y métodos. Se utilizaron 10 perros adultos, a los cuales se les inoculó veneno de abeja mediante una picadura cutánea controlada. De cada animal se extrajo una muestra de sangre previa y los 15 y 300 minutos post inoculación. Se registró la presión arterial sistólica (PAS), diastólica (PAD), media (PAM) y de pulso (PP) desde 15 minutos previos hasta 45 minutos posteriores a la inoculación. Resultados. El recuento de eritrocitos, el hematocrito y la concentración de hemoglobina se redujeron a los 15 minutos post-inoculación (p<0.05), retornando a valores basales al tiempo 300. El recuento de reticulocitos disminuyó al tiempo 15 en relación al tiempo 0 (p<0.05), manteniéndose bajo a los 300 minutos. Se observó una disminución del recuento relativo de eosinófilos a los 300 minutos relación al tiempo 0 (p<0.05). La media de la PAS a los minutos 3, 15, 30 y 39 fueron inferiores a la del minuto -15, y en la PAD, las medias de los minutos 15, 42 y 45 fueron inferiores a del minuto 9 (p<0.05). A su vez, la PAM y la PP permanecieron constantes (p>0.05). Conclusiones. La picadura cutánea de abejas produce un descenso transitorio del recuento de eritrocitos, hematocrito y concentración de hemoglobina, junto con una disminución en el recuento de reticulocitos y del recuento relativo de eosinófilos, sin alterar mayormente la presión sanguínea.
Antioxidant Activity of Syzygium polyanthum Extracts
Authors: Hidayati Mutia Devi , Ersam Taslim , Shimizu Kuniyoshi , Fatmawati Sri
Published: April 2017

Antioxidant activities of Syzygium polyanthum leaves extracts (methanol, ethyl acetate, dichloromethane and n-hexane) were evaluated by using DPPH (2,2-diphenyl-2-picrylhydrazyl) and ABTS (2,2’-azinobis (3-ethylbenzothiazole-6-sulfonic acid) methods. The methanol extract showed the highest antioxidant activity of DPPH assay among extract with IC50 value of 44.35 mg/mL. In addition, methanol extract also showed the highest antioxidant activity of ABTS assay among extracts with IC50 value of 17.69 mg/mL. This study indicated that the methanol extract of S. polyanthum leaves is potential as antioxidant.
Docking Sulochrin and Its Derivative as α-Glucosidase Inhibitors of Saccharomyces cerevisiae
Authors: Lestari Wening , Dewi Rizna Triana , Kardono Leonardus Broto Sugeng , Yanuar Arry
Published: April 2017

Sulochrin is known to have an activity as inhibitors of the α-glucosidase enzyme. In this report interaction of sulochrin to the active site of the α-glucosidase enzyme from Saccharomyces cerevisiae was studied by docking method. The crystal structure of α-glucosidase from S. cerevisiae obtained from the homology method using α-glucosidase from S. cerevisiae (Swiss-Prot code P53341) as a target and crystal structure of isomaltase from S. cerevisiae (PDB code 3A4A) as a template. These studies show that sulochrin and sulochrin-I could be bound in the active site of α-glucosidase from S. cerevisiae through the formation of hydrogen bonds with Arg213, Asp215, Glu277, Asp352. Sulochrin-I has stability and inhibition of the α-glucosidase enzyme better than sulochrin. The iodine atom in the structure of sulochrin can increase the activity as an inhibitor of the α-glucosidase enzyme.
Cinnamic Acid Derivatives as α-Glucosidase Inhibitor Agents
Authors: Ernawati Teni , Radji Maksum , Hanafi Muhammad , Mun’im Abdul , Yanuar Arry
Published: April 2017

This paper reviews biological activity of some cinnamic acid derivative compounds which are isolated from natural materials and synthesized from the chemical compounds as an agent of α-glucosidase inhibitors for the antidiabetic drug. Aegeline, anhydroaegeline and aeglinoside B are natural products isolated compounds that have potential as an α-glucosidase inhibitor. Meanwhile, α-glucosidase inhibitor class of derivatives of cinnamic acid synthesized compounds are p-methoxy cinnamic acid and p-methoxyethyl cinnamate. Chemically, cinnamic acid has three main functional groups: first is the substitution of the phenyl group, second is the additive reaction into the α-β unsaturated, and third is the chemical reaction with carboxylic acid functional groups. The synthesis and modification of the structure of cinnamic acid are very influential in inhibitory activity against α-glucosidase.
Synthesis and In Vitro Evaluation of C-methylcalix[4]resorcinaryl octacinnamate and C-methylcalix[4]resorcinaryl octabenzoate as the Sunscreen
Authors: Ngurah Budiana I Gusti M. , Jumina Jumina , Anwar Chairil , Sunardi Sunardi , Mustofa Mustofa
Published: April 2017

The present study was aimed to synthesize and evaluate sunscreen activity of C-methylcalix[4]resorcinaryl octacinnamate and C-methylcalix[4]resorcinaryl octabenzoate. The target compounds were synthesized in 2 steps. They were a synthesis of C-methylcalix[4]-resorcinarene via acid catalyzed the condensation of resorcinol and acetaldehyde by using HCl catalyst, followed by esterification using cinnamoyl chloride and benzoyl chloride. The characterization of the target compounds was performed by IR, 1H-NMR, 13C-NMR, and LC-MS spectrometers. The sunscreen activity test was conducted by spectroscopic method and MTT-assay. Commercial sunscreen p-amino benzoic acid (PABA) was used as a comparator to the MTT assay. The sunscreen activity test used spectroscopic showed that C-methylcalix[4]resorcinaryl octacinnamate and C-methylcalix[4]resorcinaryl octabenzoate can absorb the ultraviolet radiation between 280 and 320 nm (UV-B) with the maximum absorption at 290 nm (ε = 31.535 M-1 cm-1) and 282 nm (ε = 42.217 M-1 cm-1), respectively. The results of MTT-assay indicated that the IC50 of C-methylcalix[4]resorcinaryl octacinnamate, C-methylcalix[4]resorcinaryl octabenzoate and PABA are 12.006, 20.568 and 12.564 ppm, respectively, it means that the order of sunscreen activity is C-methylcalix-[4]resorcinaryl octacinnamate, PABA and C-methylcalix[4]resorcinaryl octabenzoate.
Design of Indicator Strip Using Polystyrene (PS) and Polymethylmethacrylate (PMMA) for Detection of Diclofenac Sodium in Traditional Pain Relief Herbal Medicines
Authors: Dalli Ibrahim , Ramdhani Danni , Hasanah Aliya Nur
Published: April 2017

Diclofenac sodium is one of analgesic which added to herbal medicines to enhance the effects. One of a qualitative method that is easy, efficient and simple is an indicator strip test. Indicator strip based polystyrene (PS) and polymethylmethacrylate (PMMA) was made to detect of diclofenac sodium which misused in traditional pain relief herbal medicine. Indicator strip was made by reagent blending method with specific reagents, copper sulfate (CuSO4), ferric chloride (FeCl3) and vanillin sulfate. The principle of the indicator strip in detecting diclofenac sodium is with the occurrence of a color reaction. The PS and PMMA were made in the concentration of 5, 7.5 and 10% and the mixture of PS and PMMA 1:5 and 1:6 respectively with a ratio of solvent and reactant 6:4; 7:3 and 8:2. The best indicator strip is PMMA-CuSO4 5% (7:3), PMMA-FeCl3 5% (7:3) and PMMA-Vanillin sulphate 7.5% (7:3). The detection limit of the PMMA-CuSO4 5% (7:3) was at 50 ppm, PMMA-FeCl3 5% (7:3) showed detection limit of 12,500 ppm and PMMA-vanillin sulfate 7.5% (7:3) showed detection limit of 500 ppm. All indicator strips stable up to 29 weeks. The indicator strip can be used as an alternative method to detect diclofenac sodium in herbal medicine.
Synthesis of TiO2/Carbon Nanoparticle (C-dot) Composites as Active Catalysts for Photodegradation of Persistent Organic Pollutant
Authors: Syafei Dedri , Sugiarti Sri , Darmawan Noviyan , Khotib Mohammad
Published: April 2017

TiO2/C-dot composites were synthesised by sol-gel method and  investigated as catalysts for photocatalytic degradation of persistent organic pollutants (perchloroethylene, PCE). The composites photoluminescence properties was shown by visual analysis and the synthesis product was characterized by XRD, FTIR, fluorescence spectrophotometer, and UV-Vis spectrophotometer. Degradation of PCE 0.1% (v/v) in the aqueous phase was investigated under sunlight irradiation for 2 h. Photodegrade efficiency of PCE was determined by GC. Composites of TiO2/C-dot 2.5% (w/w) was succesfully to degrade PCE under sunlight irradiation and its photodegrade efficiency was up to 89.45%.
Theoretical Study of Palladium Membrane Reactor Performance During Propane Dehydrogenation Using CFD Method
Authors: Ghasemzadeh Kamran , Alinejad Milad Mohammad , Ghahremani Milad , Zeynali Rahman , Pourgholi Amin
Published: April 2017

This study presents a 2D-axisymmetric computational fluid dynamic (CFD) model to investigate the performance Pd membrane reactor (MR) during propane dehydrogenation process for hydrogen production. The proposed CFD model provided the local information of temperature and component concentration for the driving force analysis. After investigation of mesh independency of CFD model, the validation of CFD model results was carried out by other modeling data and a good agreement between CFD model results and theoretical data was achieved. Indeed, in the present model, a tubular reactor with length of 150 mm was considered, in which the Pt-Sn-K/Al2O3 as catalyst were filled in reaction zone. Hence, the effects of the important operating parameter (reaction temperature) on the performances of membrane reactor (MR) were studied in terms of propane conversion and hydrogen yield. The CFD results showed that the suggested MR system during propane dehydrogenation reaction presents higher performance with respect to once obtained in the conventional reactor (CR). In particular, by applying Pd membrane, was found that propane conversion can be increased from 41% to 49%. Moreover, the highest value of propane conversion (X = 91%) was reached in case of Pd-Ag MR. It was also established that the feed flow rate of the MR is to be the one of the most important factors defining efficiency of the propane dehydrogenation process.
Microscopic Observation of Solid-Liquid Reaction: A Novel Laboratory Approach to Teaching Rate of Reaction
Authors: Setiabudi Agus , Wahyudin Asep , Yuliani Galuh , Mocerino Mauro
Published: April 2017

The importance of observation in science and science education has triggered this laboratory development study that investigated the value of an observation kit as a new approach to teaching rate of reaction in general chemistry class. The kit consists of a digital microscope, a “chemical reactor”, and a tailor-made computer application and was used to video-record a solid-liquid reaction and to produce a series of two dimensional solid images that indicate the extent of reaction. The two dimensional image areas were calculated by the computer application and using the assumption that the image area was directly proportional to the mass of the solid, a plot of solid mass versus time could be obtained. These steps have been tested in several solid-liquid reaction systems, with the reaction of solid magnesium oxide with nitric acid solution resulting in the best images which were transferable to rate of reaction data, i.e. a plot of solid MgO mass as a function of time. The plot can be used to explain rate of reaction concepts including average, instantaneous, and initial rate. Furthermore, the effect of concentration on reaction rate could also be explained. This study showed that the observation kit and the generated data set have the advantage of allowing students to clearly and repeatedly visualise a solid-liquid reaction and relate this with the concept of rates of reactions. The observation kit also allows teachers and students to extend its application into inquiry based experiments.
An Endowment, Commodity, and Prospect Theory Perspective on Consumer Hoarding Behavior
Authors: King Diana , Devasagayam Raj
Published: April 2017

This study investigated the preconditions that drive hoarding behaviors when consumers perceive a shortage in supply and are faced with other marketing stimuli indicating product scarcity. Pat research shows that hoarding behaviors exists due to the acknowledgement of the scarcity of products that
previously had been in excess, and consumer response to such scarcity. Endowment Effect, Commodity Theory, and the Prospect Theory were used as the basis for our conceptual framework. Data was obtained from a random sample of 297 individuals and subjected to statistical analyses. Our findings indicated that perceived perishability and scarcity of items that are valued, elicit a reaction in
consumers who have an aversion to risk due to the prospect of losing an item of value. Losses were intensified when perceived perishability and scarcity were established through urgency in advertising resulting in higher buying rates. Our findings can help marketing managers acquire more knowledge of purchase motives, satisfaction, and feelings of uniqueness gained through hoarding. Furthermore, once an understanding of what motivates consumers to accelerate their purchase behavior under perceived perishability and scarcity conditions is obtained, pricing and inventory strategies (indeed the entire marketing mix) can be strategically designed to meet the needs of the customer.
COMPARISON OF FENTANYL AND DEXMEDETOMIDINE AS AN ADJUVANT TO BUPIVACAINE IN SUPRACLAVICULAR BRACHIAL PLEXUS BLOCK: A RANDOMIZED-DOUBLE BLIND PROSPECTIVE STUDY
Authors: Karan Daisy , Swaro Swastika , Banerjee Swarna
Published: April 2017

ABSTRACTObjectives: Supraclavicular block of brachial plexus provides complete and reliable anesthesia for upper limb surgeries. Using adjuvant to localanesthetics, blocks can be prolonged to long durations. Peripheral nerve blocks thus help in avoiding the hazards of general anesthesia. We comparedthe sensory blockade, motor blockade, and duration of analgesia with the addition of fentanyl or dexmedetomidine to bupivacaine for supraclavicularbrachial plexus block.Methods: A total of 50 American Society of Anesthesiologist’s Physical Status I and II patients scheduled for elective upper limb surgeries undersupraclavicular brachial plexus block were divided into two equal groups in a randomized double-blinded fashion. Group BF received 30 mlbupivacaine with fentanyl 50 µg and Group BD received 30 ml bupivacaine with dexmedetomidine 50 µg. The characteristics for anesthesia andanalgesia were assessed in both groups.Results: Duration of sensory and motor block was 363.4±38.36 minutes and 357±36.77 minutes, respectively, in Group BF while it was452.96±77.12 minutes and 441.52±48.46 minutes in Group BD. There was a statistically significant difference in onset of sensory and motorblock between the two groups. The duration of analgesia (time to requirement of rescue analgesia) in Group BD was longer than in Group BF(471.44±65.88 minutes vs. 366.48±38.02 minutes) with (p<0.0001). There were minimum hemodynamic disturbances and side effects in any groupexcept for Grade 3 sedation score which was more in Group BD.Conclusion: Dexmedetomidine, when added to bupivacaine in supraclavicular brachial plexus block, enhanced the duration of sensory and motorblock and also the duration of analgesia, more than when fentanyl was added to bupivacaine.Keywords: Fentanyl, Dexmedetomidine, Bupivacaine, Supraclavicular brachial block.
ASSESSMENT OF EPILEPSY CLASSIFICATION USING TECHNIQUES SUCH AS SINGULAR VALUE DECOMPOSITION, APPROXIMATE ENTROPY, AND WEIGHTED K-NEAREST NEIGHBORS MEASURES
Authors: P Sunil Kumar , Rajaguru Harikumar
Published: April 2017

ABSTRACTObjective: The main aim of this research is to reduce the dimension of the epileptic Electroencephalography (EEG) signals and then classify it usingvarious post classifiers. For the evaluation and easy treatment of neurological diseases, EEG signals are used. The reflection of the electrical activitiesof the human brain is obtained by the measurement of potentials in EEG. To study and explore the brain functions in an exhaustive manner, EEG is usedby both physicians and scientists. The study of the electrical activity of the brain which is done through EEG recording is a vital tool for the diagnosis ofmany neurological diseases which include epilepsy, sleep disorders, injuries in head, dementia etc. One of the most commonly occurring and prevalentneurological disorders is epilepsy and it is easily characterized by recurrent seizures.Methods: This paper employs the concept of dimensionality reduction concepts like Fuzzy Mutual Information (FMI), Independent ComponentAnalysis (ICA), Linear Graph Embedding (LGE), Linear Discriminant Analysis (LDA) and finally Variational Bayesian Matrix Factorization (VBMF).The epilepsy risk levels are also classified using post classifiers like Singular Value Decomposition (SVD), Approximate Entropy (ApEn) and WeightedKNN (W-KNN) classifiers.Results: The highest accuracy is obtained when LDA is combined with Weighted KNN (W-KNN) Classifiers and it is of 97.18%. Conclusion: Thus the EEG signals not only represent the brain function but also the status of the whole body. The best result obtained was whenLDA is engaged as a dimensionality reduction technique followed by the usage of the W-KNN as post classifier for the classification of epilepsy risklevels from EEG signals. Future work may incorporate the possible usage of different dimensionality reduction techniques with various other types ofclassifiers for the perfect classification of epilepsy risk levels from EEG signals.Keywords: FMI, ICA, LGE, LDA, W-KNN, EEG
CANDIDATE GENES ASSOCIATED WITH POLYCYSTIC OVARY SYNDROME IN ASIAN POPULATIONS: A RESEARCH REVIEW
Authors: Vg Abilash
Published: April 2017

ABSTRACTPolycystic ovary syndrome (PCOS) is a complex genetic condition and is a highly prevalent heterogeneous syndrome of clinical and biochemicalandrogen excess. The disease has genetic as well as environmental involvements. The normal menstrual cycle results from a coordination of hormonalsecretion and signaling within the hypothalamic pituitary-ovarian axis. Alterations in the normal cycle or irregularity in menstrual cycle result inamenorrhea, abnormal uterine bleeding, etc. The main causes are PCOS, hormonal imbalance, drugs, nutritional deficiency, personality, some geneticfactors, and many more. Women with PCOS are often resistant to the biological effects of insulin and, as a consequence, may have high insulin levels.Women with PCOS are at risk for type 2 diabetes, high cholesterol, and high blood pressure. Obesity also appears to worsen the condition. The impactof the syndrome on an individual varies significantly based on several factors such as the severity of the components, comorbidities, and life courseconsiderations. In addition, each individual experiences the syndrome in the context of her own reproductive health, metabolic, and quality-of-lifeconcerns. Hirsutism, obesity, and infertility are common complaints. This review article gives a detailed account on the association of candidate genesassociated with PCOS in South Asian population.Keywords: Anti-mullerian hormone, Growth/differentiation factor 9, The bone morphogenetic protein, Follicle-stimulating hormone, Follistatin,Cytochrome p450, Polymerase chain reaction-restriction fragment length polymorphism.