bluuebunny/crossref_metadata_2025 huggingface dataset:
Land-use and Energy Practices on US Golf Courses
Authors: Shaddox Travis W. , Unruh J. Bryan , Johnson Mark E. , Brown Clark D. , Stacey Greg
Published: May 2023

Golf facilities require a large area and consume energy to operate. As such, golf facilities have the potential to influence ecosystems and contribute to national and regional energy demands. The objective of this study was to document the land-use and energy practices of US golf facilities in 2021 and to determine if changes have occurred since 2005. A survey was distributed via e-mail to 13,938 US golf facilities, with 1861 responding. From 2005 to 2021, the projected acres of maintained turfgrass declined by 14.2%, whereas the median maintained turfgrass acreage declined by 3.0% indicating the decline in projected acres was likely a result of facility closures. In 2021, water features, turfgrass, and natural areas accounted for 92% of the total projected facility acres. More golf facilities used cleaner energy sources, such as natural gas and solar-electric, and fewer golf facilities used gasoline and diesel in 2021 than in 2005. The percentage of golf facilities at which behavioral changes were implemented to decrease energy use declined but design changes increased from 2005 to 2021. Golf facilities became more land and energy efficient from 2005 to 2021 by reducing the acreage of maintained turfgrass and increasing the use of clean energy sources, but room for improvement still exists in human behaviors that affect energy use.
Explaining Interactions Between Malaysia’s Dewan Rakyat and Foreign Affairs: A Study of Parliamentary Behaviour Between 1959 and 2019
Authors:   Research School for Southeast Asian Studies, Xiamen University, China, Lam Choong Wah
Published: May 2023

Interactions and power relations between the Malaysian Parliament and foreign affairs have long been neglected by academics. This article is an attempt to fill this gap. The Malaysian Parliament, being the highest legislative authority in the nation, is empowered to enact laws related to foreign and security affairs as well as hold the government to account. Drawing on Philip Norton’s discourse on power relations between parliamentarians and the legislature, this article argues that Malaysian parliamentarians’ check and balance over the executive’s foreign authority is minimal due to a weak parliamentary institution compared with its British counterpart. The best the parliamentarians can achieve is to induce the government to pay attention to their concerns, while a second option is to make foreign issues the business of parliament through tabling adjournment motions to dictate the agenda. There was only one successful instance of a parliamentary intervention in stopping a military asset procurement.
Modified Delphi analysis of the clinical guideline “Sedation of patients in the departments of anesthesiology, intensive care and intensive care”
Authors: Lakhin Roman E. , Andreenko A. A. , Vlasenko A. V. , Martynov D. V. , Lazarev V. V. , Ovezov A. M. , Gorbachev V. I. , Leiderman I. N. , Belkin A. A. , Fisher V. V. , Lomivorotov V. V. , Kuzkov V. V. , Shifman E. M. , Grigoryev E. V. , Popov A. S. , Magomedov M. A. , Yaroshetskiy A. I.
Published: May 2023

INTRODUCTION: Approaches to sedation in the departments of anesthesiology, intensive care and intensive care have changed over the past 20 years. In 2020, the guidelines “Sedation of patients in the departments of anesthesiology, intensive care and intensive care” were placed in the rubric of clinical recommendations. OBJECTIVE: To contribute to improving the quality of planned updating of recommendations with the help of a modified Delphi analysis of the provisions and quality criteria of the current version of the document published in the rubricator of clinical recommendations of the Ministry of Health of the Russian Federation. MATERIALS AND METHODS: We used a modified Delphi method with two rounds of questionnaires to develop a consensus. The agreement of specialists was reached in three stages: preparatory, discussions and the development of a consensus conclusion. To conduct the assessment, a questionnaire was created consisting of 3 blocks: assessment of the provisions of the clinical recommendation; assessment of the quality criteria of the clinical recommendation and an overall assessment of the clinical recommendation. The assessment was made on the basis of the Likert scale. Median, fashion and weighted average score were calculated. If, when evaluating the provisions and quality criteria of a clinical recommendation, the median value or mode of any provision was less than 7, the weighted average score was less than 70 %; the median value or mode of quality criteria is less than 7.5, the weighted average score is less than 75 %, then this provision (quality criterion) should be recommended for processing. RESULTS: The assessment of the provisions and criteria was carried out in the first round of discussion. At the second round of discussion, comments and recommendations were finally developed for the developers of the methodological recommendation. Consensus was reached during two rounds of modified Delphi analysis. As a result of the analysis, 16 out of 21 provisions and 5 out of 6 quality criteria were agreed, the rest required processing. CONCLUSIONS: As a result of an independent assessment by experts, 5 provisions and 1 quality criterion were recommended for processing. Comments and recommendations on all these provisions and quality criteria of the methodological recommendation “Sedation of patients in the departments of anesthesiology, intensive care and intensive care” were also agreed.
Analysis of the structure of bacteremia and sensitivity to antibiotics of microorganisms isolated in intensive care units in an emergency hospital in the period from 2003 to 2021: a retrospective observational study
Authors: Bykov А. О. , Suvorova M. P. , Protsenko D. N. , Yakovlev Sergey V. , Ignatenko O. V. , Burmistrova E. N. , Sychev I. N. , Krotenko N. P.
Published: May 2023

INTRODUCTION: Creation of protocols for effective empiric antimicrobial therapy is impossible without the analysis of current antibiotic susceptibility data. OBJECTIVE: Analysis of changes in the etiological significance of the leading pathogens of bacteremia in the ICU (intensive care unit) in the period from 2003 to 2021, and their sensitivity to antibiotics; study of the types of carbapenemases in the most relevant pathogens — Klebsiella pneumoniae and Acinetobacter baumannii. MATERIALS AND METHODS: The analysis included all microorganisms isolated from the blood of patients who were in the medical 12-bed ICU in the emergency hospital of Moscow in the period from 2003 to 2021. Identification of microorganisms and determination of antibiotic sensitivity were carried out with an automatic PHOENIX analyzer and a standardized disco diffusion method. Detection of carbapenemases was carried out by PCR (polymerase chain reaction). RESULTS: In the period from 2003 to 2021, 17 034 blood samples were examined, from which 6372 microorganisms were isolated. During this period, the proportion of Gram-negative microorganisms increased from 21.0 to 52.8 %, mainly due to K. pneumoniae from 1.0 to 24.5 % and A. baumannii from 0 to 9.1 %. The resistance of these microorganisms to carbapenems increased significantly from 2008 to 2021: K. pneumoniae from 2.3 % to 70.3 %, A. baumannii — from 7.5 to 99.5 %. K. pneumoniae produced the following types of carbapenemases: OXA-48 (73.8 %), KPC (6.2 %), NDM 1.5 %, NDM + OXA-48 (15.4 %), KPC + OXA-48 (3.1 %). All A. baumannii strains produced OXA-40 type carbapenemase. OXA-48 carbapenemase producers were resistant to colistin and tigecycline in 14.6 and 44.8 %, and to ceftazidime/avibactam in 4.2 %. CONCLUSIONS: The increased level of antimicrobial resistance in recent years among Gram-negative microorganisms isolated from blood is a very significant problem in the ICU. Most K. pneumoniae strains are characterized as multi-drug resistant, about 10 % of the strains were categorized as extremely-drug resistant (XDR) or pan-drug resistant. All strains of A. baumannii belong to the category of XDR.
ORTHODONTIC-SURGICAL TREATMENT OF CLASS III MALOCCLUSION WITH MANDIBULAR ASYMMETRY: A CASE REPORT
Authors: Rai Wijdane Ait , El Fatmi Kadiri , Mohamed Faouzi Azaroual
Published: May 2023

Class III skeletal malocclusion may present several etiologies, among which maxillary deficiency is the most frequent. Bone shift may have an unfavorable impact on esthetics, which is frequently aggravated by the presence of accentuated facial asymmetries. This type of malocclusion is usually treated with association of Orthodontics and orthognathic surgery for correction of occlusion and facial esthetics. This report presents the treatment of a patient aged 19 years with Class III skeletal malocclusion, having narrow maxilla, bilateral posterior crossbite, accentuated negative dentoalveolar discrepancy in the mandibulary arch, and maxillary and mandibular midline shift. Clinical examination also revealed maxillary hypoplasia, increased lower one third of the face, concave bone and facial profiles and facial asymmetry with mandibular deviation to the left side. The treatment was performed in three phases: presurgical orthodontic preparation, orthognathic surgery and orthodontic finishing. In reviewing the patients final records, the major goals set at the beginning of treatment were successfully achieved, providing the patient with adequate masticatory function and pleasant facial esthetics.
CLINICAL AND ETIOLOGICAL STUDY OF LOWER EXTREMITY ULCER CASES
Authors:   Assistant Professor, Department of General Surgery, M R Medical College, Kalburagi., Patil Jyothi , K. Reddy Chinmayee ,   Junior Resident, Department of General Surgery, M R Medical College, Kalburagi., Rajiv Reddy J.C ,   Consultant, Department of General Surgery, Ram Raj Hospitals, Hyderabad., Rashmi Reddy J.C ,   Consultant, Neuro Physician, Ram Raj Hospitals, Hyderabad., Reddy Male Bharath ,   Assistant Professor, Department of Radio-Diagnosis, Kanachur Institute of Medical Sciences, Deralakatte, Mangalore.
Published: May 2023

Background:Because of their chronic nature, lower extremity ulcers are the most frequent in our population. By maintaining an upright position, the lower extremities are vulnerable to damage and have their circulation strained. This has implications for researchers and surgeons who have been worried about the causes of their prevalent incidence and the difficulties in curing them. A researcher is looking at the causes of lower extremity ulcers. Methods:During the study period, 50 patients with various forms of lower extremity ulcers were admitted to the surgical ward. The instances were extensively studied and evaluated in depth. If a clinically dubious case existed, the diagnosis was determined only after histological testing. Results:Venous 13 (26%) instances were detected in the present, with male (10) and female (3) contributions. The majority of cases (47%) are males between the ages of 41 and 60 years.High saphenous vein ligation with vein stripping (23%) and conservative (15%) therapy was the most prevalent surgical methods utilised to treat Venous ulcers. Conclusions:Venous ulcers are the most common kind of leg ulcer today, with the highest morbidity. At various levels, the surgical procedures try to prevent venous reflux.Interdisciplinary management of patients with ulcers, educating patients on foot care and the importance of seeking early medical advice.
LARGE RENAL CALCULUS HIDINGA RENAL TUMOR TYPE SQUAMOUS CELL CARCINOMA ABOUT A RARE CASE AND REVIEW OF LITERATURE
Authors:   Department of Urology, Hassan II University Hospital, Fez, Morocco., Chama Othman ,   Faculty of Medicine, Pharmacy and Dentistry of Fez, Sidi Mohammed Ben Abdellah University, Morocco., Alami Ouaddane Rhyan ,   Department of Urology, Hassan II University Hospital, Fez, Morocco.,   Faculty of Medicine, Pharmacy and Dentistry of Fez, Sidi Mohammed Ben Abdellah University, Morocco., Ahsaini Mustapha ,   Department of Urology, Hassan II University Hospital, Fez, Morocco.,   Faculty of Medicine, Pharmacy and Dentistry of Fez, Sidi Mohammed Ben Abdellah University, Morocco., Mellas Soufiane ,   Department of Urology, Hassan II University Hospital, Fez, Morocco.,   Faculty of Medicine, Pharmacy and Dentistry of Fez, Sidi Mohammed Ben Abdellah University, Morocco., Eddine EL Ammari Jalal ,   Department of Urology, Hassan II University Hospital, Fez, Morocco.,   Faculty of Medicine, Pharmacy and Dentistry of Fez, Sidi Mohammed Ben Abdellah University, Morocco., Fadl Tazi Mohammed ,   Department of Urology, Hassan II University Hospital, Fez, Morocco.,   Faculty of Medicine, Pharmacy and Dentistry of Fez, Sidi Mohammed Ben Abdellah University, Morocco., Jamal El Fassi Mohammed ,   Department of Urology, Hassan II University Hospital, Fez, Morocco.,   Faculty of Medicine, Pharmacy and Dentistry of Fez, Sidi Mohammed Ben Abdellah University, Morocco., Hassan Farih Moulay ,   Department of Urology, Hassan II University Hospital, Fez, Morocco.,   Faculty of Medicine, Pharmacy and Dentistry of Fez, Sidi Mohammed Ben Abdellah University, Morocco.
Published: May 2023

Through this clinical study we present a rare case of renal squamous cell carcinoma discovered incidentally during a nephrectomy on dumb kidney plus large renal lithiasis in a patient with a history of recurrent upper urinary tract infections on kidney stones. The reason for consultation was chronic pain in the right flank. The CT scan showed a huge kidney stone of 10 cm long axis with pyelic infiltration in relation to her history of right renal pyelonephritis. The discovery of squamous cell carcinoma was on the anatomopathological specimen.
SKIN SURFACE BRACHYTHERAPY FOR CUTANEOUS T LYMPHOMA: CASE REPORT AND REVIEW OF LITERATURE
Authors:   Radiation Oncology Department, Oncology Hospital Hassan II University, Fes, Morocco., Alaoui G. Chrifi , K. Soussy ,   Radiation Oncology Department, Oncology Hospital Hassan II University, Fes, Morocco., M. Elbaraka ,   Medical Physics Unit, Fez Hassan Ii University Hospital Center, Morocco., Z. Bennouna ,   Dermatology Department, Hassan II University Hospital, Fes, Morocco., W. Hassani ,   Radiation Oncology Department, Oncology Hospital Hassan II University, Fes, Morocco., F.Z Farhane ,   Radiation Oncology Department, Oncology Hospital Hassan II University, Fes, Morocco., Z. Alami ,   Radiation Oncology Department, Oncology Hospital Hassan II University, Fes, Morocco., FZ Mernissi ,   Dermatology Department, Hassan II University Hospital, Fes, Morocco., T. Bouhafa ,   Radiation Oncology Department, Oncology Hospital Hassan II University, Fes, Morocco.
Published: May 2023

Cutaneous T cell lymphomas (CTCLs) are a heterogeneous group of extranodal non-Hodgkins lymphomas that are characterized by a cutaneous infiltration of malignant monoclonal T lymphocytes.At the early stages, CTCLs are often misdiagnosed as benign skin conditions and the treatment is still not well codified. We report the diagnostic and therapeutic path of a case of cutaneous anaplastic large celllymphoma located in the left forearm treated by skin surface brachytherapy(SS-BT) in theRadiotherapy-Brachytherapy department of the HASSANII university hospital center in FES. In our patient SS-BT provided us an excellent local control andgood cosmetic results.
DOES KANGAROO MOTHER CARE IMPROVE BREASTFEEDING PRACTICES? A SINGLE INSTITUTION EXPERIENCE ON HEALTHY TERM NEONATES
Authors:   Final Year Resident, Department of Paediatrics, A.J. Institute of Medical Sciences, Mangalore, Karnataka, India., Ann Sabu Megha , Ashvij Shriyan ,   Assistant Professor, Department of Paediatrics, A.J. Institute of Medical Sciences, Mangalore, Karnataka, India., T. Soans Santosh ,   Professor and HOD, department of Paediatrics, A.J. Institute of Medical Sciences, Mangalore, Karnataka, India.
Published: May 2023

Early initiation of breastfeeding following birth has several advantages such as weight gain, improved immune status and better development. However, for exclusive breastfeeding to be successful, appropriate latching is necessary. Several studies across the globe have noted that improper feeding techniques have resulted in early breastfeeding cessation.Kangaroo mother care is a tool to help provide skin-to-skin contact, especially in preterm infants, to develop bonding, prevent hypothermia and allow adequate breastfeeding. KMC is seldom practiced in healthy term neonates. However, we propose that KMC can help improve breastfeeding practices in this subgroup of infants. The aim of this study is to compare the LATCH scores in term neonates that receive KMC (group A) and dont receive KMC (group B).
LA DISJONCTION DE LA SYMPHYSE PUBIENNE A PROPOS DUNE PATIENTE APRES UN ACCOUCHEMENT DYSTOCIQUE
Authors:   Departement de Gynecologie Obstetrique du CHU Mohammed VI de Marrakech, Maroc., Coulibaly Fatoumata , El-Aziz Soukaina ,   Departement de Gynecologie Obstetrique du CHU Mohammed VI de Marrakech, Maroc., Aboulfalah Abderrahim ,   Departement de Gynecologie Obstetrique du CHU Mohammed VI de Marrakech, Maroc., Bassir Ahlam ,   Departement de Gynecologie Obstetrique du CHU Mohammed VI de Marrakech, Maroc., Soummani Abderraouf ,   Departement de Gynecologie Obstetrique du CHU Mohammed VI de Marrakech, Maroc.
Published: May 2023

La disjonction de la symphyse pubienne est une entite rare, qui se definie par un elargissement au niveau de larticulation inter-symphysaire estime superieur a 10 mm. Cette entite necessite une prise en charge specialisee en cas de douleurs intenses et handicapantes. Ici on rapporte un cas dune patiente presentant des douleurs pelviennes intense avec impotence du MI droit a H 4 dun accouchement dystocique, lexamen clinique a objective une douleur provoquee a la palpation de la symphyse pubienne. Le diagnostic a ete confirme par une radiologie du bassin de face objectivant un elargissement de la symphyse pubienne de 30 mm, la prise en charge therapeutique a consiste en une mise sous decharge et anti-coagulation preventive avec un traitement antalgique a base de codeine et AINS ainsi qun bandage. Levolution etait favorable. Lobjectif de notre travail est de mettre en evidence les caracteristiques surtout pronostic afin de faire un diagnostic precoce de cette entite.
ROLE OF ANTIBIOTIC IMPREGNATED CEMENT COATED INTRAMEDULLARY NAILING IN ORTHOPAEDICS
Authors:   Professor and HOD, Department of Orthopaedics, Sri Aurobindo Medical College and Post Graduate Institute, Indore, Madhya Pradesh, India., Choudhari Pradeep , Baurasi Charchit ,   Senior Resident, Department of Orthopaedics, Sri Aurobindo Medical College and Post Graduate Institute, Indore, Madhya Pradesh, India., Mehta Deepesh ,   PG Resident, Department of Orthopaedics, Sri Aurobindo Medical College and Post Graduate Institute, Indore, Madhya Pradesh, India., Patidar Manish ,   PG Resident, Department of Orthopaedics, Sri Aurobindo Medical College and Post Graduate Institute, Indore, Madhya Pradesh, India.
Published: May 2023

Introduction:Traditionally,thetreatmentstrategyofinfectednon-unionconsistedofsurgicaldebridementandthenasecondprocedureforstability.Theuseofanantibioticcementednailingforinfectednon-unionoftibiaandfemurfracturesavoidstheneedofmorethan1procedureasthenailprovidesstabilityandallowshigherconcentrationofantibioticatthelocalsitethanisachievablewithsystemicantibioticsandisassociatedwithfewersideeffect. MaterialandMethods:Thisisaprospectivestudyof12patientswithdiaphysealfractureoftibiaorfemurwithsignsofinfectionwhoweretreatedusingantibioticcementednailing.Patientswerefollowedupmonthlyfor3months.Infectioncontrolwasevaluatedintermsofclinical,haematologicalandmicrobiologicalparameters. Results:Atthetimeofpresentation11outof12patientshadpusdischarge,whilelocalriseoftemperaturewasthereinallpatients.MostcommonorganismthatwasisolatedincultureswasStaphylococcusaureus.ESRandCRPwaselevatedin9patients.At3monthsfollowupvisit,9outof12patientsresolvedallsignsofinfectionwhile1hadpersistentpositiveculturereports.ESRandCRPwasraisedin3and2patientsrespectively. Conclusion:Antibioticcementednailingdeliversahighconcentrationofantibioticsatthelocalsitewithoutcausinganysystemictoxicityalongwithprovidingstabilityatthefracturesite,therebyconvertingatwo-stageprocedureintoasinglestageprocedurewhichalsoavoidscomplicationsofexternalfixatorhavingbetterpatientcompliance.
EFFICACY OF LOCAL INFILTERATION ANALGESIA IN POST OPERATIVE PAIN MANAGEMENT AND EARLY REHABILITATION IN TOTAL KNEE ARTHROPLASTY
Authors: Pingle Pravishi , Jain Arjun
Published: May 2023

TKR is a surgical procedure in which an artificial joint or prosthesis replaces a damaged knee joint. The primary indication for TKR is pain, followed by functional limitation. Usually, a personÂ’s daily activities must be substantially affected by pain and functional limitations for him or her to be considered a candidate for TKR. The most common risks and complications associated with TKR are deep venous thrombosis, infection, stiffness, loosening, and osteolysis. To prevent deep venous thrombosis, patients are treated with heparin prophylactically and/or given support stockings to wear. Patients are also given antibiotics for 24 hours after surgery to minimize the risk of infection. Stiffness is another associated complication. In most patients, it can be avoided by keeping the knee moving in the days and weeks following surgery.
STUDY ON CLINICAL PRESENTATIONS, LEVEL OF STRESS & ROLE OF FAMILY ENVIRONMENT AMONG DISSOCIATIVE DISORDER PATIENTS
Authors:   Department of Psychiatry Sri Aurobindo Medical College & PG Institute-Indore (M.P)., Rahul Gour , Srikanth Reddy ,   Department of Psychiatry Sri Aurobindo Medical College & PG Institute-Indore (M.P)., Hiral Kotadia ,   Department of Psychiatry Sri Aurobindo Medical College & PG Institute-Indore (M.P)., Jitendra Keshwani ,   Department of Psychiatry Sri Aurobindo Medical College & PG Institute-Indore (M.P)., Apurva Tiwari ,   Department of Psychiatry Sri Aurobindo Medical College & PG Institute-Indore (M.P)., Pawan Rathi ,   Department of Psychiatry Sri Aurobindo Medical College & PG Institute-Indore (M.P).
Published: May 2023

Background: Dissociative disorder is a stress-related disorder usually present in adolescent and younger age group. It is also accompanied with significant impairment in activity of daily living and family relationship. Family environment plays important role in initiation and maintenance of symptoms and this put significant burden on family. To assess different types of clinical presentations, level of stress and role of family environment among dissociative disorder patients and check for association between sex distributions. Material and Method: This cross-sectional descriptive study was carried out on patients with primary diagnosis of dissociative disorder as per ICD-10 criteria coming to psychiatry outpatient department of Sri Aurobindo Medical College and Postgraduate Institute, Indore a premier tertiary care hospital situated at northern part of India, covering, and serving a large catchment area, during the period of 18 months. 80 patients were recruited for the purpose of study. The procedure and rationale for the study was explained to all subjects and informed written consent were taken in their local language. Patients were included after fulfilling inclusion criteria from both inpatients and outpatient department of psychiatry. Result: In our study, majority of the patients (48.75%) belonged to the age group 18-30 years. The prevalence rates decrease with age. 37.5% of the patients were between the age group 31-40 years and 13.75% were over the age of 40 years. In a study of 80 patients with dissociative (conversion) disorder, 77.5% were females and 22.5% were male. There was female predominance. Conclusion: Dissociative disorders are more common in females than males. It always occurs in the background of increased stressful life events and in the presence of significant psychosocial stressors. Future studies should be undertaken in a large sample with a prospective design to examine the impact of disease duration and other mediators, such as family type and coping style.
IMPROVEMENT OF THE SECURITY SYSTEM AGAINST POLLUTANTS USING A CIRCULAR CONE
Authors:   Department Of Physics, College of Science, Qassim University, Buraidah, Saudi Arabia., Yahya Z.
Published: May 2023

This study focuses on the improvement of a security system against the pollutants dispersing from Industrial chimneys. In order to simulate the system, we study numerically a turbulent flow generated by a heated open cone at the extremities. Different control parameters were used to improve the thermal and dynamic behavior of the considered flow. In this study, the interaction of pollutants with its surrounding environment simulated by the cone walls was investigated. This study was focused on convection, which is natural, turbulent, steady, 2-D, incompressible flow passing through a vertical conical channel with a heated source at the center of the cone inlet that performed uniform heating at a constant temperature. The interior of the conical wall channel was reheated via the thermal radiation emitted by the hot source. The studied system was mathematically presented by the continuity, Navier stokes, energy and K-epsilon equations. The computational fluid dynamics analysisand ANSYS-FLUENT software were used. The optimal cone can provide further control of the pollutants velocity at the exit. The thermal and dynamic profiles exhibitedgood stability and homogeneity at the cone exit.
DETECTION OF FREQUENCY OF BACTERIA CARBAPENEMASE PRODUCING IN PEDIATRIC CASES IN TERTIARY CARE HOSPITAL
Authors:   Postgraduate Student, Department of Microbiology, Peoples College of Medical Sciences and Research Centre, Bhopal, MP., Chouhan Manish , Kumar Vinay ,   Assistant Professor, Department of Pediatrics, Peoples College of Medical Sciences and Research Centre, Bhopal, MP., Jain Khyati ,   Professor, Department of Microbiology Peoples College of Medical Sciences and Research Centre, Bhopal, MP., Prabhu K. Tukaram ,   Assistant Professor, Department of Microbiology Peoples College of Medical Sciences and Research Centre, Bhopal, MP., Sadawarte Kalpana ,   Professor and Head, Department of Microbiology Peoples College of Medical Sciences and Research Centre, Bhopal, MP.
Published: May 2023

Introduction:New strains of bacterial species are now showing multidrug resistance & causing nosocomial and community-acquired infections. The rapid rise in the prevalence and clinical consequences of infection caused by bacteria that produce carbapenemase is a global health concern in pediatric cases. Material And Method:This study was done in bacteriology laboratory of PCMS & RC, from to February 22 to February 23. Total 268 samples of pediatric patients were included in the study. Identification of bacteria was done by conventional methods. Primary screening of Carbapenemase producing bacteria was done by Kirby-Bauer disk diffusion method by using meropenem (10ug) &Imipenem (10ug) as per as CLSI guideline. Confirmation of Carbapenemase producing bacteria was done by 3 different methods using Boronic acid test, Imipenem-EDTA synergy test & Combination disc test method. Result:In our study the frequency of carbapenemase producing bacteria were found to be 52 % in pediatric cases. Imipenem-EDTA synergy test & Combination disc test method were found to be more effective in detecting carbapenemase producing bacteria into Boronic acid test. Conclusions:The present study demonstrates the presence of high level of Multidrug resistant Among carbapenemase producing GNB isolated from pediatric cases as assessed in 2023 in central India.We conclude that the prevalence of phenotypically confirmed carbapenemase producer amongGram negative bacteria is quite useful.The comparison of multiple phenotypic assays for the detection of carbapenemaseproducing bacteria indicates that the Combination disc test and Imipenem-EDTA test provides the highest rate of positivity.
THE STUDY OF CONDUCTION BLOCKS IN ACUTE MYOCARDIAL INFARCTION PATIENTS ADMITTED IN TERTIARY CARE HOSPITAL IN CENTRAL INDIA: A PROSPECTIVE OBSERVATIONAL STUDY
Authors: Borlepawar Pooja , Shingade Pravin
Published: May 2023

Background: Acute Myocardial infarction (AMI) is one of the most fatal diseases of human community. Various types of conduction blocks (CB) develop following an AMI. Hence the present study was undertaken to study the various types of conduction blocks in acute ST elevation myocardial infarction (STEMI) patients admitted in Tertiary care hospital in central India. Method: A total 140 patients of age â‰¥18 years with symptoms and signs suggestive of AMI having ECG changes consistent with STEMI and rise in cardiac markers presenting with conduction disturbances were included in the study. Results: Among the 140 patients, 62.2% survived, 37.8% were non-survivors.Highest incidence of conduction blocks (28.57%) and maximum non-survivors (22.64%) were in age group of 51-60 years. Most common risk factor among non survivors was HTN+Dyslipidemia 70%, followed by HTN+ DM+ Dyslipidemia (69.23%). Among 22 non-survivors in AWMI, maximum non-survivors seen in killips class 2. In IWMI out of 17 non-survivors, 10(53.8 %) seen in killips class 1. In ALWMI 3 (75%) non-survivors seen in killips class 1. In ASWMI maximum non-survivors 4(66.7%) seen in killips class 3. In IRPWMI non survivors seen in class 2,3,4 (33.33% each). In patients with QRBBB maximum non-survivors seen in killips class 2. Maximum non-survivors seen in killips class1 seen the in patients with CHB. Multivariate analysis of variables showed that patients having CHB, first degree AV block, QRBBB and patients with killips class4 have significant independent prediction for in hospital non-survivors. Highest Non-survivors in QRBBB (41.51%) and in AWMI (52.83%). Conclusion:The conduction blocks are associated with higher in-hospital mortality rate and are important predictors of poor outcome in patients with AMI (STEMI).
ECTOPIC MAMMARY TISSUE IN THE AXILLARY REGION: A CASE REPORT AND DISCUSSION OF DIAGNOSIS AND MANAGEMENT
Authors:   Department of Gynecology-Obstetrics, Mohammed IV University Hospital., Bellejdel I. , Lamzouri O. ,   Department of Gynecology-Obstetrics, Mohammed IV University Hospital., Taheri H. ,   Department of Gynecology-Obstetrics, Mohammed IV University Hospital., Saadi H. ,   Department of Gynecology-Obstetrics, Mohammed IV University Hospital., Mimouni A. ,   Department of Gynecology-Obstetrics, Mohammed IV University Hospital.
Published: May 2023

Ectopic breast tissue, or supernumerary breast tissue, is a rare congenital anomaly that can occur along the milk line, extending from the axilla to the groin. Ectopic breast tissue can undergo the same changes as normal breast tissue, including hormonal changes during pregnancy and lactation, as well as the development of benign or malignant tumors. Herein, we present a case of ectopic breast tissue presenting as axillary masses in a young woman. The patient was a 32-year-old woman who presented with two axillary masses that appeared during lactation after her first and second pregnancies, and now had reappeared. The masses had the consistency of breast tissue and were confirmed as supernumerary bilateral breasts on echomamography. Although supernumerary breasts are usually benign and asymptomatic, they can sometimes become cancerous. Therefore, surgical excision is often recommended, particularly in cases where the mass is symptomatic or growing rapidly.
A STUDY ON CONSUMER BEHAVIOUR TOWARDS SHOPPING MALLS IN ANDHRA PRADESH (WITH SPECIAL REFERENCE TO VISAKHAPATNAM CITY)
Authors:   Principal, Department of Commerce, Government Degree College, Chinturu-533 347, Alluri Sitarama Raju District, Andhra Pradesh, India., Ratna Manikyam K. , Naidu M.Y. ,   Lecturer, Department of Commerce and Management Studies, Government College (Autonomous), Rajahmundry- 533 105, Andhra Pradesh, India., Haritha Lochana Y.V. ,   Lecturer, Department of Commerce and Management Studies, Government College (Autonomous), Rajahmundry- 533 105, Andhra Pradesh, India.
Published: May 2023

Indian retail industry has emerged as one of the most dynamic and fast-paced industries due to the entry of several new players. It accounts for over 10% of the countrys gross domestic product (GDP) and around 8% of the employment. India is the worlds fifth-largest global destination in the retail space. The sizeable middle class and nearly unexplored retail market in India are the main attractive factors for international retail behemoths seeking to move into newer markets, which will help the Indian Retail Industry, grow more quickly. The urban Indian consumers purchasing power is increasing, and branded goods in categories like apparel, cosmetics, footwear, watches, beverages, food, and even jewellery are gradually evolving into business and leisure that are well-liked by the urban Indian consumer. India has the third-highest number of e-retail shoppers (only behind China, the US). The phenomenon called shopping centre or shopping mall is rocking India - metros and now even the smaller towns are buzzing with the mall mania. Modern retail format i.e. shopping malls are characterized by professionally managed large format stores, providing goods and services that appeal to consumers, in an ambience that is conducive for shopping. The recent surge in the growth of shopping malls is changing the way people shop. Mall culture in India and especially in Andhra Pradesh has been growing with an incredible pace. Just a few years back, people had to make a choice among shopping, movies or hanging out on a holiday but thanks to our malls, all these jobs can be performed at the same time, under the same roof and that too with a wonderful experience. The possibility of shopping for clothes, shoes and grocery, while simultaneously having provision for eating and entertainment in the form of movies or video game parlors, has been a convenient experience for the consumers. This paper aims to study the key factors that influence consumer behaviour towards shopping malls. The specific objective of this paper is to study consumers buying tactic, shopping priority during shopping at mall in Chennai city. The main aim of this study is to analyze different attributes of layouts, accessibility and availability of services in malls in Visakhapatnam City and to examine the attributes offered by the shopping malls which influence the customers in Visakhapatnam.
AWARENESS AND CONSUMPTION OF PREBIOTICS AND PROBIOTICS AMONG ADULT (MALE/FEMALE) IN AL AHSA REGION
Authors:   Clinical Nutrition Department., Alqurashi Tahani , Mariam Bi Bi ,   College of Applied Medical Sciences-Al Ahsa, Female Branch., K. Rajappan Suchithra ,   College of Applied Medical Sciences-Al Ahsa, Female Branch., Alomair Majd ,   King Saud bin Abdulaziz University for Health Sciences., Alhammadi Reema ,   King Saud bin Abdulaziz University for Health Sciences., Alsubaie Razan ,   King Saud bin Abdulaziz University for Health Sciences., Buaeshah Noor ,   Kingdom of Saudi Arabia., Alnajdy Nada ,   Kingdom of Saudi Arabia., Alsafi Reneem ,   Kingdom of Saudi Arabia.
Published: May 2023

Introduction: Public awareness and interest in food that is highly related to their health benefits are flourishing. Even though there is a gap between the biomedical sciences experiments and the business of marketing, the accessibility of health-promoting channels/media leads the consumer to seek healthier food and drinks. Pre/probiotics have a big role in management and protection of gastrointestinal infection, allergic disease. The aim of study is to find out the awareness and consumption of prebiotics and probiotics among adults (male/female) in Al-Ahsa region. Method: Cross sectional study was conducted in Al Ahsa, KSA among adults using structured questionnaire which included questions related to demographic, anthropometric, frequency of consumption of prebiotics and probiotics and about health status. A clear inclusion and exclusion criteria data was set before the data collection. Arabic version of Questionnaire along with ethical consent form was distributed through social media total of 450 participated in the study with their consent, based on inclusion and exclusion criteria data of 384 respondents was included for statistical analysis, Data was collected, checked for completeness, and further analysis of the data was done by using (SPSS) software version 20, Descriptive statistics was calculated including frequencies and proportions for categorical variables. Approval for this study was obtained from KAIMRC and IRB Result: Majority of the participants are not aware of the term prebiotic (64.3%) and probiotic (61.2%). However, pre/probiotics products (apples, leeks, garlic, yogurt) are available in all the supermarkets which (kefir and yakult) are rarely available, also the consumption of these products are in high percentage on regular basis (28% & 35%) daily and weekly basis, respectively. Significant association of age, gender, and educational level for awareness & consumption. Conclusion: Pre/probiotics products are available abundantly in all the Al-Ahsa supermarket also the consumption rate, most of them aware of the health benefits of these products. However, the term Pre/probiotics is not very familiar to the population of al Ahsa indicating need for increasing awareness about these products also its health benefits.
LABYRINTHINE FISTULA : A SEVERE COMPLICATION OF CHOLESTEATOMA
Authors:   Neuroradiology Department, Hospital of Specialties, Faculty of Medicine and Pharmacy, Mohamed V University, Rabat, Morocco., Sahar Merbouh , Mohamed Traore Wend-Yam ,   Neuroradiology Department, Hospital of Specialties, Faculty of Medicine and Pharmacy, Mohamed V University, Rabat, Morocco., Amal Lahfidi ,   Neuroradiology Department, Hospital of Specialties, Faculty of Medicine and Pharmacy, Mohamed V University, Rabat, Morocco., Elkhamlichi Amina ,   Neuroradiology Department, Hospital of Specialties, Faculty of Medicine and Pharmacy, Mohamed V University, Rabat, Morocco., Touarssa Firdaous ,   Neuroradiology Department, Hospital of Specialties, Faculty of Medicine and Pharmacy, Mohamed V University, Rabat, Morocco., El Kettani Najwa ,   Neuroradiology Department, Hospital of Specialties, Faculty of Medicine and Pharmacy, Mohamed V University, Rabat, Morocco., Fikri Meryem ,   Neuroradiology Department, Hospital of Specialties, Faculty of Medicine and Pharmacy, Mohamed V University, Rabat, Morocco., Jiddane Mohammed ,   Neuroradiology Department, Hospital of Specialties, Faculty of Medicine and Pharmacy, Mohamed V University, Rabat, Morocco.
Published: May 2023

The labyrinthine fistula is a severe complication of chronic otitis media withcholesteatoma. It is the consequence of a progressive erosion of the endochondral bonecovering and closing the labyrinth by the cholesteatoma matrix. As thelabyrinth is connected to the cochlea, a labyrinthine fistula can lead to sensorineural hearingloss in addition to vertigo. Computed tomography imaging of the petrous bones issystematic, specifying the seat and extension of the cholesteatoma, and evaluating the extentof bone lysis.We report the case of a young female patient who presents a chronic otitis media withcholesteatoma complicated by a labyrinthinefistula and a left temporal brain abscess.
Quality of latrines and willingness to improve them in rural Ethiopia
Authors: Mamo Biruk Getachew , Novotný Josef , Admasie Amha
Published: May 2023

Ethiopia recorded the world's fastest increase in latrine coverage over the past two decades, but it was largely achieved by the adoption of latrines that do not meet basic hygienic standards. Therefore, this study aims to examine the quality of latrines and their upgrading at household level through a case study from the Loka Abaya district, South Ethiopia. Of the initially sampled 549 households, 422 (77%) had private latrines, and a survey was administered among them. The data were characterized descriptively, and correlates of the latrine quality and willingness to improve were analysed. The average latrine quality score in the sample was only 2.8 of the maximum six quality dimensions. Despite the low quality of latrines, 63% of respondents were satisfied with their sanitation situation. Both past improvements and plans to improve latrines were frequently reported. However, these reported changes mostly involved regular maintenance or reconstructions of collapsed latrines. No substantial upgrading of the functionality was identified. We identified inadequate awareness about the means of hygienic sanitation, implying the importance of community education. Demand for as well as supply of hygienic sanitation products are further constrained by the low purchasing power of households implying a need for sanitation subsidies.
Investigation of a basic nitrification–denitrification biofiltration system for primary wastewater treatment
Authors: Hassen Wafa , Ben Rejab A. , Hassen B. , Jedidi N. , Hassen A.
Published: May 2023

The study aimed to eliminate the nitrogen and its main residual forms from municipal wastewater by using a biofilter system adapted for a small community. The biological nitrification/denitrification system used involved two successive polyvinyl chloride (PVC) columns; a first gravel column (C1) loaded with primary wastewater followed by a second sandy column (C2). A complex biofilm development on the gravel and sand materials has been confirmed by scanning electron microscope. The efficiency of chemical oxygen demand (COD), BOD5, TSS, and NH4+-N removal from primary wastewater reached 75.3, 88.4, 83.5, and 88.1%, respectively, at the exit of the sandy column (C2). Inoculation with activated sludge as an external carbon source allowed an improvement in the nitrate removal, from 80 to 28 mg/L N-NO3. However, sludge inoculation showed non-significant fecal coliforms and Streptococcus contamination, and the biofilter appeared as effective for total nitrogen removal and a bacterial abatement of over 3.2 U-log10. The average bacterial removal seemed directly related to the applied load of about 50 cm/day and a tertiary disinfection treatment, such as UV-C254 irradiation, is needed as a preventive step to ensure the removal of pathogens.
Study of synthesis and characterization of raw bagasse, its char and activated carbon prepared using chemical additive
Authors: Raut Ekta R. , Bedmohata (Thakur) Monita A. , Chaudhari Archana R.
Published: May 2023

This paper reports the use of naturally available raw material as sugarcane bagasse (SB) to prepare cost-effective activated carbon. Activated carbon preparation from SB by using ZnCl2 was carried out by chemical activation method. The raw bagasse, its char and activated carbon were characterized on the basis of iodine number, carbon, hydrogen, nitrogen analysis, Fourier-transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), thermogravimetric analysis (TGA) and Brunauer–Emmett–Teller (BET) surface area to check their effectiveness. During activated carbon synthesis, the impregnation ratio of SB and ZnCl2 was maintained at 1:1–1:3 and activation temperature was in the range of 600–900 °C for 1 h. From the characterization study, the highest iodine adsorption of activated carbon was found to be 1140.69 mg/g with a 1:2 ratio at 900 °C whereas char gives an iodine number of 529.63 mg/g at the same temperature. The BET surface area of raw bagasse, its char and activated carbon (SB-Zn2-900) obtained was 4.30, 514.27 and 1386.58 m2/g, respectively, which shows charrification and chemical activation improves surface area. The optimum ratio of impregnation and activation temperature was found to be 1:2 at 900 °C. In this work, activated carbon was successfully prepared and obtained product has better characteristics than previously reported studies.
New Tiaoxin Recipe Alleviates Energy Metabolism Disorders in an
APPswe/PS1DE9 Mouse Model of Alzheimer’s Disease
Authors: Hu Yiran , Xing Sanli , Huang Yan , Chen Chuan , Shen Dingzhu , Chen Jiulin
Published: May 2023

Background:

Alzheimer's disease (AD) is a typical neurodegenerative disease with a
complex etiology. Until now, there has been no effective treatment available for AD; however, improving
energy dysmetabolism, the key pathological event in the early stage of AD, can effectively
delay the progression of AD.

Objective:

This paper aims to investigate the therapeutic effect and potential mechanism of the new
Tiaoxin recipe on early AD.

Methods:

APP/PS1 mice were divided into a model group, a new Tiaoxin recipe group, and a
donepezil group, and C57/BL mice were used for the control group. Mouse cognitive and learning
abilities were tested using the Morris water maze test and a new object-recognition experiment.
The 42 amino acid form of amyloid β peptide (Aβ1–42) content was detected by enzyme-linked
immunosorbent assay, the senile plaque area was detected by thioflavin S staining, and the senescence-
associated β-galactosidase (SA-β-gal)–positive area was detected by chemical staining. Also,
the adenosine triphosphate (ATP), nicotinamide adenine dinucleotide (NAD+), and nicotinamide
adenine dinucleotide hydride (NADH) contents were detected using a biochemical method,
and the cluster of differentiation 38 (CD38) and silent mating–type information regulation 2 homolog
3 (SIRT3) protein expression levels were detected by immunofluorescence and Western blot
analysis.

Results:

Compared with those of the control group, the learning and memory abilities of the model
group were impaired; the senile plaque deposition, Aβ1–42 content, and SA-βgal–positive staining
area were increased; the ATP concentration, NAD+ concentration, and NAD+/NADH ratio were
decreased; the CD38 protein expression level was increased; and the SIRT3 protein expression
level was decreased. Following intervention with the new Tiaoxin recipe, the learning and memory
abilities were improved; the senile plaque deposition, Aβ1–42 content, and SA-βgal–positive area
were reduced; the ATP concentration, NAD+ concentration, and NAD+/NADH ratio were increased;
CD38 protein expression was decreased, and SIRT3 protein expression was increased.

Conclusion:

This study shows that the new Tiaoxin Recipe can improve cognitive ability and reduce
the Aβ1-42 content and senile plaque deposition in APP/PS1 mice, which may occur through
the downregulation of CD38 protein expression, upregulation of SIRT3 protein expression, restoration
of the NAD+ level, promotion of ATP synthesis, mitigation of energy metabolism disorders.
Herbal Drugs Inducing Autophagy for the Management of Cancer:
Mechanism and Utilization
Authors: Rajput Shivam , Sharma Pramod Kumar , Malviya Rishabha
Published: May 2023

When compared to chemical medicines, herbal medicines have the greatest therapeutic
benefit while having fewer harmful side effects. Many different components in herbs have an anticancer
impact, but the exact mechanism of how they work is unknown. Some herbal medicines
have even been shown to trigger autophagy, a process that has shown promise as a potential cancer
treatment. In the past ten years, autophagy has come to be recognised as a crucial mechanism in
the maintenance of cellular homeostasis, which has led to the discovery of its implications in the
pathology of the majority of cellular environments as well as human disorders. Autophagy is a
catabolic process that is used by cells to maintain their homeostasis. This process involves the
degradation of misfolded, damaged, and excessive proteins, as well as nonfunctional organelles,
foreign pathogens, and other cellular components. Autophagy is a highly conserved process. In
this review article, several naturally occurring chemicals are discussed. These compounds offer
excellent prospects for autophagy inducers, which are substances that can hasten the death of cells
when used as a complementary or alternative treatment for cancer. It requires additional exploration
in preclinical and clinical investigations, notwithstanding recent advances in therapeutic medications
or agents of natural products in numerous cancers. These advancements have been made
despite the need for further investigation.