bluuebunny/crossref_metadata_2025 huggingface dataset:
Optimasi Jalur Transfer Data dari HTTP menjadi MQTT pada IoT menggunakan Cloud Services
Authors: Permatasari Claudia Felicia , Dhika Harry
Published: March 2021

At this time, in the era of technological development and information that incresingly very fast, introduced smart device systems that can help any stuff and conditions of human work, this technology is known as IoT or the abbreviation of Internet of Things Technology. With the existence of IoT systems, every devices connected to microcontroller, and we can communicate to domonitoring stuff and work more easier anytime, anywhere, and with variety of gadgets that we have. However, it must be supported by the existence of a stable supporting internet access. The HTTP protocol is used to connect communication networks and data traffic between devices on IoT has laxity with effectiveness, supports faster data transmission capabilities, resources intensive used, complicated message formats, large data sizes, and the process of checking traffic for each data consume a lot of time. This exactly affects for the performance of related systems. Referring to these constraints, this paper will discuss the comparison betw en HTTP and MQTT protocols in terms of protocol models, speed of data transmission, size of messages sent, and optimal use for each protocol. Implementation of this system test also involves the implementation of RabbitMQ as a Message Broker between the sender / publisher (smart phone) and the receiver / subscriber (IoT device) which is tasked with storing temporary data before being distributed to the receiver. Not only that, RabbitMQ also has a role to handle if the internet connection is unstable or temporarily dead, the server can store data temporarily on RabbitMQ and will return the data to the IoT device if the internet connection is more stable. This such a system mechanism can certainly be a solution for us to against the problem of data loss due to unstable internet connections. Users/ clients are no longer afraid that data will be lost because all data will be accommodated in RabbitMQ stored place, not influenced by the stability of the internet network connection. In this case, RabbitMQ must be in container environment, for that we also need a docker when installing a broker which is useful as a media containerize. With the docker container, installing RabbitMQ becomes so easy because the installation is not really done from the beginning (as we knew that potentially quite complicated), but we will only install containers that have been filled by RabbitMQ.
Aplikasi Augmented Reality Berbasis Vuforia dan Unity Pada Pemasaran Mobil
Authors: Mega Fransisca Kristina
Published: March 2021

In the current era of globalization, world development is increasingly difficult. Companies are required to be more innovative and creative in the marketing strategy of goods or services. Marketing strategies using media that create statistics cannot provide real-time feedback. Marketing strategies using media will increasingly attract the attention of consumers and become more interactive for consumers. Application of Augmented Reality technology based on Unity and Vuforia on marketing strategies that provide the best solutions in the automotive industry business world, consumers can see cars that are supported in realtime, types of cars that are not available in showrooms and marketing is done at certain events. Augmented Reality technology converts 2D images into 3D, this of course gives satisfaction to customers to see the cars offered. The results of this study use a marketing strategy with the application of Augmented Reality technology based on Unity and Vuforia to make it easier for consumers to see c rs in realtime and also provide convenience for manufacturers in terms of marketing and provide improvements in supplying their products.
EMPREENDEDORISMO E INOVAÇÃO NUM CONTEXTO DE CRISE: REVISÃO DE LITERATURA
Authors: Pacheco Michelle Gonçalves Marques , Campos Waleska Yone Yamakawa Zavatti , Quintão Marcelo Jucá , Polidoro Paula Rodrigues Almeida , Rosa Luciana Aparecida Barbieri da
Published: March 2021

O presente artigo trata-se de uma revisão da literatura que tem como objetivo identificar os temas mais pesquisados, no período de 2015 a maio/2020, na literatura de empreendedorismo e inovação num contexto de crise. A pesquisa foi realizada em três etapas e a última envolveu o acoplamento bibliográfico por autores a fim de identificar a similaridade de temas publicados. Com isso foi possível identificar três grandes categorias de temas publicados ao longo do período de recorte, que são: alternativas para o empreendedorismo em períodos de crise e pós-crise; influência das políticas públicas no empreendedorismo e inovação em perídos de crise; e fatores que influenciam empreendedorismo e a inovação na crise do covid-19. A partir de uma melhor compreensão dos principais temas já pesquisados novas pesquisas podem ser desenvolvidas e outras abordagens podem ser mais exploradas para ampliar o debate sobre o tema.
Foreign economic activity and its impact on the balance of payments of Ukraine
Authors:   Mykolayiv National Agrarian University, Burkovskaya Alla , Parakonnyi Dmytro ,   Mykolayiv National Agrarian University
Published: March 2021

Introduction. The payment balance is an indicator of the state and development of the national economy, systematically reflects the transactions between economic systems around the world, which allows us to assess the country’s participation in the international division of labor. It also plays an important role in the mechanism of currency regulation. Control of the payment balance in the context of implementing measures to eliminate imbalances in the economy, implementing a balanced foreign economic, monetary, exchange rate policy, establishing economically sound amounts of gold and foreign exchange reserves, developing adaptive mechanisms to attract external financing are extremely important. The problem and its solution should become the main direction of state policy of Ukraine. Purpose. The aim of this article is to study the impact of the real state of foreign economic activity on the payment balance of Ukraine and analysis of the reviewed impact indicators. Results. The article considers the concepts and individual indicators of the payment balance of Ukraine and shows the components of the payments balance. The main indicators of foreign trade, including the volumes of imports and exports and their dynamics, have been reviewed in detail. The current state of Ukrainian foreign economic activity in general has been analyzed. The concept of the payment balance has been indicated and the connection between the change in the payment balance depending on the change of certain indicators of Ukraine’s foreign economic activity, which are closely interrelated, has been determined. Conclusions. The main factor that negatively affects Ukraine’s payment balance is the large balance of goods deficit. The strategy to reduce the payment balance deficit should include the following elements: taking the necessary measures to eliminate internal economic imbalances; to guarantee the provision of export credits to producers, insurance against economic and political risks, the introduction of a preferential depreciation regime for fixed assets and the provision of financial benefits and other loans in exchange for the fulfillment of specific obligations of the export program; use international legal standards to regulate the payments balance; regulation of expenditures and revenues of the state budget, the use of risk insurance instruments in the financial system; increase revenue and revenue rates to increase trademark patents, licenses, and references to scientists and technicians.
Innovations as a tool of adaptation of agricultural enterprises to climate change
Authors:   Uman National University of Horticulture, Burliai Oleksandr , Smertenyuk Igor ,   Uman National University of Horticulture
Published: March 2021

Introduction. The article considers the role of innovation as a tool for adaptation of agricultural enterprises to climate change. The study found that climate change has become an integral attribute of modernity, which has a significant impact on economic development. Purpose. The aim of the article is to study the consequences of climate change for the activities of agricultural enterprises, to develop directions for the adaptation of agricultural holdings to climate change and the role of innovation in this process. Results. In Ukraine, the climate tends to increase air temperature, and the consequence of warming is an increase in the number of dangerous weather events. Climate change is the result not only of natural processes but also of human activity. Climate change has special consequences for the agricultural sector, the feature of which is a significant dependence on natural and climate change. Among them we can note the extension of the growing season for 10-15 days, the acceleration of spring field work for about 3 weeks, the extension of the grazing season, increasing the yield of thermophilic crops and more. However, there are also negative consequences – a shortage of water, the emergence of new thermophilic species of pests and weeds, reducing the area under crops in cool and humid climates, and others. The main directions of adaptation of agricultural enterprises to climate change are highlighted. Conclusions. The main tool for agricultural enterprises to adapt to climate change should be the introduction of innovations: the use of nanotechnology and biotechnology, digitalization of production and improvement of management processes, introduction of new varieties of crops and animal breeds, improvement of technical support, diversification of energy sources and production technologies.
Shadow Economy: Causes and Ways to De-shadow Economic Processes
Authors:   Sumy State University, Bukhtiarova Alina , Semenog Andrii ,   Sumy State University, Mykhalova Alona ,   Sumy State University
Published: March 2021

Introduction. The spread of the shadow economy is a significant obstacle to the sustainable development of Ukraine’s economy and its entry into the world community. It negatively affects all economic processes. In Ukraine, the scale of the shadow economy has reached a critical level, so it is vital to find ways to minimize the shadow economy as essential prerequisites for increasing economic security of the state. Purpose. The purpose of the article is to discover the essence of the concept of the shadow economy, to find out the leading causes of the shadow economy and identify ways to de-shadow economic processes. Results. The article analyzes the approaches to the interpretation of the essence of the concept of the shadow economy on the basis of the analysis of the foreign researchers` scientific achievements. The characteristic of its constituent elements has been presented. It has been determined that the shadow economy can take the form of covert, informal and illegal. The level of the shadow economy in Ukraine has been considered. It has been substantiated that the shadow sector of the economy exists regardless of the level of development of the national economy. At the same time, in some countries, it has no significant impact on the economy (5-12% of GDP), and in others – has a detrimental effect on all socio-economic processes (over 30% of GDP). ). It has been emphasized that Ukraine belongs to the second group of countries with a high level of the shadow economy. Also, the main factors that lead to the formation of the shadow economy have been substantiated. Ways to overcome the shadow economy to strengthen Ukraine’s economic security have been proposed. Conclusions. To overcome the negative consequences of the process of shadowing the economy, it is necessary to develop and implement several measures to combat it. The state policy on the de-shadowing of Ukraine’s economy requires the development and application of a set of tools, assessment of the impact (social and economic effects) on the real and financial sectors of the economy, stimulation of entrepreneurial activity. An essential factor in the success of de-shadowing is political support for this complex process, a sequence of actions to reform society, avoid populism and punish irresponsible activities of officials, change the mentality of citizens towards awareness of civic position and involvement in the overall process.
The Essence and Architectonics of the Fiscal Space of the State
Authors:   European University, Kryhan Yurii
Published: March 2021

Introduction. The objective civilizational processes of modern times transform national economies, significantly influence the formation of a new paradigm of state development as a competitive participant in interstate communications in the global dimension. The financial relations in the state, which are the result of its financial policy, take place in the search for coherence of the interests of its internal subjects. Taxpayers are trying to reduce the tax burden, citizens need quality public goods as a fair result of tax refunds, and the state is trying to effectively replenish resources, the main source of which is taxes, to fulfill its functions and develop competitive participation in the interstate communications of the globalized world. Under these conditions, the fiscal space is formed, the essence of which still remains unclear. Purpose. The purpose of the article is a comprehensive substantiation of the theoretical foundations of the essence and architecture of the fiscal space of Ukraine. Results. It has been proved that the transformation of the fiscal space of the state is a systematic change in the essential properties of the environment of interaction between the subjects of fiscal policy, aimed at effective mobilization of budget revenues and their rational use to obtain a positive impact on socio-economic development and welfare. It has been substantiated that the fiscal space belongs to the components of the public finance system, including revenues, expenditures and borrowings. Conclusions. In our opinion, the main idea of the transformation of the fiscal space is in two equally important areas: its effective formation for the allocation of additional financial resources and effective use to increase the efficiency of reasonable areas of budget expenditures. In these interconnected processes, a balance is sought between the divergent interests of the state and taxpayers as the main subjects in the fiscal space. This balance can be achieved on the basis of established public trust, which is an important indicator of a harmonious society.
Priorities of Ecologically Oriented Economic Development of the Agricultural Sector
Authors:   Mykolayiv National Agrarian University, Kurepin Vyacheslav , Gorbunova Karine ,   Mykolayiv National Agrarian University, Velikhovska Alla ,   Mykolayiv National Agrarian University
Published: March 2021

The article considers the main factors of anthropogenic impact that affect the environment; a number of major environmental challenges in the agricultural sector that affect the stable economic growth of agricultural production are identified. It is established that the transformation processes in the life of society are contradictory in relation to the interaction of nature and society, significantly exacerbate the degrading changes in the environment. Violations of the technology of cultivation, storage and application of mineral fertilizers, their properties and chemical composition, imperfection of their use have led to increased negative impact on certain components of the biosphere, soil environment, the environment and man. Practice shows that intensive technologies for growing field crops increase the possibility of soil contamination with fertilizer residues, pesticides, herbicides and other toxicants. The presence of toxic substances in the soil is accompanied by their accumulation in surface and groundwater. This is one of the main environmental factors that affect the quality of products and soil quality. Ensuring environmental safety should be decided in the light of world experience, taking into account the specifics of the country’s geographical location, ensuring that the economic interests of agricultural producers are aligned with the environmental requirements of environmental protection. In view of this, the problem of increasing the efficiency of agricultural production through its greening, starting with the organization of the rational use of natural resources as the main means of production, becomes especially relevant. An important element of economic activity of agricultural enterprises is to take into account environmental factors in order to increase the economic efficiency of agricultural production and preserve ecosystems.
Assessment of Transport Infrastructure Development Level of Ukraine
Authors:   Mykolayiv National Agrarian University, Lesik Irina
Published: March 2021

The purpose of the article is to create a basic model of conducting an analytical assessment of infrastructure development efficiency. The basic model allows assessing the level of current infrastructure condition which provides production and social dimension of its stable development. The article substantiates the necessity of conducting an analytical assessment of infrastructure development level which identifies its weaknesses and determines the potential of improving its performance indicators. Integral estimation of road infrastructure efficiency is proposed. To assess the problems of infrastructure development provision the comparative analyses within the proposed model are made as well as with the Data envelopment analysis (DEA) method. The results of the research allow discovering the causes of harmful phenomena in the system of management and development, identifying major trends and prospects of development.
The Need for Transformations of Enterprises’ Mechanism of Economic Security Management in the Context of the Fourth Industrial Revolution Risks Spread
Authors:   Bohdan Khmelnytsky National University of Cherkasy, Matukhno Yulia , Kutsenko Dmytro ,   Bohdan Khmelnytsky National University of Cherkasy
Published: March 2021

Introduction. The state of economic security of the enterprise determines its ability to develop its own potential and maintain the level of competitiveness, as well as ability to counteract the negative impact of external and internal environment and prevent the risks that are characteristic of it. The number of risk factors for the normal operation of domestic enterprises has increased in the context of the trends spread of the Fourth Industrial Revolution. An important step in establishing a modern integrated economic security system is the formation of a management mechanism that will ensure the effectiveness of the process of identifying and neutralizing both traditional and emerging risks to industrial enterprises, many of which belongs to the critical infrastructure of the country and are therefore strategically important for maintaining industrial potential and maintaining the state of national security. Purpose. The purpose of the article is to determine the vectors of transformation of the essence, functions, main stages of creating a mechanism for managing the economic security of an industrial enterprise, able to counteract the negative consequences of the risks of the Fourth Industrial Revolution. Results. The article reveals the essence of the mechanism of economic security management and defines its main elements. It is offered to divide the functions of the mechanism of economic security management of the enterprise into preventive and anti-crisis management in order to ensure timely counteraction to the risks of the environment of the industrial enterprise. The short characteristic of the stages of industrial enterprise economic security management mechanism formation is given, features of functioning of the economic security management mechanism in the conditions of tendencies distribution of the Fourth Industrial Revolution are considered. Conclusion. As a result of studying the basics of building a modern, risk-oriented industrial enterprise economic security management mechanism, it was found that due to its elements such as methods, resources, tools and levers of economic security, it becomes possible to effectively overcome the impact of traditional and innovative risks on corporate resources of enterprises and on the success of the process of meeting the economic interests of different groups of its stakeholders. Implementation at the applied level of the outlined stages of enterprise economic security management mechanism formation allows to apply its functionality in the future to ensure economic stability, strategic prospects and competitiveness of the business structure in the risk of the Fourth Industrial Revolution.
Modular-Competence Aspect of the Teaching Process Future Economists in Accordance with the Requirements of the Bolonga Process
Authors:   Kharkiv National Technical University of Agriculture Named After Petro Vasylenko, Nagaev Viktor , Litvinchuk Svitlana ,   Mykolayiv National Agrarian University, Taikhrib Katerina ,   Mykolayiv National Agrarian University, Yablunovska Katerina ,   Mykolayiv National Agrarian University
Published: March 2021

Introduction. This article researches the didactic principles of the modular-competence approach for teaching future economists in higher education through innovative pedagogical activities. The actual issues of the innovative pedagogical activity, the competence approach for future economists learning and the specific features of modular learning are analyzed. The didactic conditions of the modular-competence approach for teaching students, which determines the quality assurance of the professional training of future specialists in higher education, are highlighted. Purpose. The purpose of this article is to study the didactic principles of forming a modular-competence approach to the training of future economists in higher education through of the Bolonga process. Results. Practical research was carried out, on the basis of which the technology of acquiring competencies by future economists while studying the modules of the discipline “Management psychology” was developed. The percentage of competencies was calculated, which is prescribed to acquire each of the two modules in the process of working with lectures, for the work with practical tasks and for the execution of individual tasks. Conclusions. It has been proved that the preparation effectiveness of future economists in the context of the Bologna Process will be significantly improved, and the formation of professional competencies of those who get higher education, provides an opportunity to successfully engage in professional activities in the sphere of future economists after graduation from higher education institutions.
The strategic directions of modernization of the mechanism for managing the regional economy
Authors:   V.O. Sukhomlynskyi Mykolaiv National University, Nazarova Liudmyla
Published: March 2021

Introduction. The article highlights the necessity to develop the main strategic directions of modernization of the mechanism for managing the regional economy. The mechanism aims to provide the relevant evaluation of the social and economic policy efficiency at the local and national levels, as well as the efficiency of the development and implementation of the regional economic tools. The author emphasizes the necessity to not only improve, but also differentiate the mechanism to manage the regional economy in order to differentiate the social and economic development. Considering constantly changing market conditions, the article determines the necessity to review the functions of regional social and economic systems within the system of the economic environment functioning, where the decisions of their stable development take place. Purpose. The purpose of the article is to determine the main strategic directions of modernization of the mechanism for managing the regional economy and the main issues of the managerial regional economic system improvement. Results. The main strategic directions of modernization of the mechanism to manage the regional economy have been researched. The main issues of the managerial regional economic system improvement have been determined. Taking into account the structured process approach, the mechanism for managing the regional economy has been developed. The development of the managerial regional economic system during the USSR period has been assessed, the main issues have been determined. The main factors to transform the regional economic mechanism in current reality have been studied. The enlarged scheme to assess the efficiency of social and economic regional development has been designed. The research findings reveal that the development of key parameters of modernization of the managerial mechanism based on the differentiation approach is important in conditions of independent functioning of territories and their decentralization. Conclusions. The author concludes that the improvement of the managerial regional economic system in conditions of their independence considers its permanent monitoring of the efficiency to manage the development of social and economic regions. The choice of differentiated managerial mechanism relevant for the regional development should be based on the data provided by the monitoring. Such approach will allow to decrease in the differentiation level and foster the increase in responsibility of regional authorities related to functioning of the territories managed.
Sufi Approaches to Education: The Epistemology of Imam Al-Ghazali
Authors: Fadhil Muhammad Yusuf , Sebgag Saliha
Published: March 2021

The goal of this paper is to explore the sufi pedagogy that aims to inculcate devout worship and happiness amongst students. Methodologically, this research is qualitative in nature and focuses on the literature of Imam Al-Ghazali. After the data has been collected, the material results are presented systematically with an epistemological analysis. The conclusions of this paper are as follows: ontologically speaking, science is not an abstraction of the object being observed, but the essence of knowledge is a divine light that radiates to the soul (al-ruh ilahiyah) that exists in all humans. Epistemologically, knowledge can be obtained through the optimization of reason. Hence, the mujahadah and the riyadhah are tasks that must be undertaken by students in order to secure the knowledge of mukasyafah. In terms of axiology, knowledge is a means to get closer to Allah, to gain happiness in the world and the hereafter. That is why the profile of the learning outcome of sufi education is ulama' akhirat; namely scholars who have the following characteristics; ‘abid, zahid, ‘alim, faqih and mukhlish.
Identification of Vernacular Architectural Typology at Raden Aria Wangsakara’s House in Banten as an Effort to Utilize Cultural Heritage Buildings
Authors: Lie Titieandy , Findanavy Rdzqo Intan , Medtry Medtry
Published: March 2021

Rumah tinggal peninggalan Raden Aria Wangsakara yang berlokasi di permukiman Lengkong, Tangerang, Banten merupakan salah satu bangunan bersejarah yang telah ditetapkan sebagai bangunan cagar budaya. Namun, seiring dengan gencarnya aktivitas pembangunan kota untuk meningkatkan nilai kawasan, terutama yang terjadi di Lengkong, hal ini berpotensi menggerus dan menghilangnya bukti sejarah serta nilai-nilai budaya kawasan tersebut apabila tidak adanya upaya pelestarian yang lebih lanjut. Penelitian terdahulu terhadap Rumah Arya Wangsakara telah lebih banyak dilakukan pada lingkup yang makro, yaitu obyek bangunan yang dikaitkan dengan konteks sejarah dan geografis kawasan. Sementara itu, dalam upaya pelestarian yang lebih teknis pada bangunan, pengetahuan membangun bangunan belum banyak dibahas. Padahal, langkah ini sangat diperlukan untuk mengetahui nilai-nilai budaya yang terkandung pada bangunan rumah Raden Aria Wangsakara melalui tipologi arsitektur bangunannya dan menentukan signifikansi bangunan yang berkontribusi untuk meluaskan khasanah arsitektur dan ketukangan. Untuk itu, langkah penelitian ini, yaitu menguraikan kesejarahan bangunan cagar budaya rumah Raden Aria Wangsakara, mengidentifikasi tipologi bangunan cagar budaya rumah Raden Aria Wangsakara melalui elemen-elemen arsitekturnya, dan menganalisa elemen-elemen arsitektural bangunan sekitar bangunan cagar budaya rumah Raden Aria Wangsakara. Hasil penelitian ini diharapkan dapat bermanfaat bagi peningkatan nilai sejarah dan budaya bangunan serta kawasan, dokumentasi catatan ketukangan, dan menginspirasi masyarakat untuk mengekspresikan upaya pelestarian melalui elemen arsitektural yang diterapkan pada bangunan atau kawasan sekitar mereka.
Features of the Formation of Humoral Immunity in Individuals with Various Clinical Manifestations of COVID-19
Authors: Platonova T. A. , Golubkova2 A. A. , Karbovnichaya E. A. , Smirnova S. S.
Published: March 2021

Relevance In the context of the new coronavirus infection (COVID-19) pandemic, research on the formation of an immune response to SARS-CoV-2 in patients with various clinical forms of this infection is of particular relevance, which is important for understanding the degree of their participation in the formation of population immunity and assessing individual immunity to SARS-CoV-2 in the future.

Aim of the study was to analyze the timing of the formation of specific antibodies to SARS-CoV-2 and the duration of their preservation in patients with a new coronavirus infection.

Materials and methods. The timing of the formation of specific antibodies of three classes (IgA, IgM and IgG) to SARS-CoV-2 in 218 patients was evaluated in the first days of the disease. Subsequently, they were re-examined at various times from the onset of the disease, from one to four times (a total of 321 control points). To assess the duration of preservation of antibodies to COVID-19 in patients who were ill, a prospective study was organized, in which 368 people participated. Screening for specific class G antibodies was performed every 2–4 weeks, within one to eight months of the onset of clinical manifestations of COVID-19. In total 919 control points. The antibodies were examined by solid-phase enzyme immunoassay using the SARS-CoV-2IgM-ELISA-BEST and SARS-CoV-2-IgG-ELISA-BEST test systems (manufactured by VECTOR-BEST JSC) and Antigma A (manufactured by Generium).

Results. In most of the examined individuals, class M and G antibodies began to form from day 10 of the disease, while class A antibodies were detected from day 5. In mild and asymptomatic forms of coronavirus infection, IgG antibodies to SARS-CoV-2 were not formed in most cases, and seroprotection levels correlated with the severity of the disease. The duration of preservation of IgG antibodies could be at least 8 months, but there were isolated cases of their elimination both after COVID-19 in the form of respiratory infection and after interstitial pneumonia. With continuing problems with COVID-19, there were no cases of recurrent disease among individuals who formed G-antibodies (including those who lost them 4-5 months after the disease) during the follow-up period.

Conclusion. Thus, according to the results of the study, important materials were obtained on the peculiarities of the formation of a humoral immune response to a new coronavirus infection. However, to fully understand the immune response to SARS-CoV-2, it is necessary to assess the avidity of IgG antibodies or their ability to neutralizing the virus, as well as to study cellular immunity in patients who have had COVID-19 but have not formed antibodies.
Assessment of the Effect of Multidrug Resistance Clostridium difficile Clinical Strains on the Dynamics of Clostridium difficile Infection Rate at Pediatric Oncological Hospital
Authors: Shvydkaya M. G. , Zatevalov A. M. , Dzhandarova D. T. , Mitrokhin S. D. , Orlova O. E.
Published: March 2021

Relevance. At the children's oncological hospital guidelines to treat patients with several groups of antibiotics at the same time, which ensures the formation of multi-resistant strains of Clostridium difficile, which have a selective advantage for the Clostridium difficile infection developing, and also cause epidemics and /or in associating with an increase in the severity of Clostridium difficile – infection.

Aims. Multidrug resistance Clostridium difficile strains and Clostridium difficile infection rate at pediatric oncological hospital.

Results. An investigation of the Clostridium difficile resistance strains carried out among children at the children's oncological hospital. 143 toxigenic strains are resistant to moxifloxacin 72.41%, clindamycin 63.72%, rifampicin 35.54%, tetracycline 26.45%, tigecycline 11.42%, vancomycin 4.4%, metronidazole 3.9%. At the same time, the increase multidrug-resistant strains proportion note at the level of 3–4% per year. However, the rate of Clostridium difficile infection among children at the oncological hospital remained at the level of 0.4% to 3.1% with a downward trend. As a result, statistical calculations showed the absence of correlation between multidrug resistance and morbidity.

Conclusions. Detection of multidrug-resistant microorganisms among toxigenic Clostridium difficile strains proves the need for further study of this problem in Russia and the advisability of monitoring Clostridium difficile infection rate and multidrug resistance Clostridium difficile strains at pediatric oncological hospitals.
Vaccines against Covid-19: Comparison, Limitations, the Decrease of Pandemic and the Perspective of Viral Respiratory
Authors: Kharchenko E. P.
Published: March 2021

Relevance. Vaccines are regarded as an effective means for control of the Covid-19 pandemic spreading and their search, analysis, and comparison of their features are important for elucidating the most safe and effective one.

Aim. At the end of 2020 two types of vaccines (viral based vaccines and mRNA vaccines) have been licensed to vaccinate. The aim is to compare their features for objective substantiation of their application.

Conclusions. As both vaccine types have high effectiveness in inducing antibodies to SARS-Cov-2 (in more 90% recipients) the utility of each vaccine type in blocking the Covid-19 pandemic spreading is beyond doubt. In both vaccine types eventually S protein is the antigen source, and they have limitations for vaccination. In comparison with the vector vaccines mRNA vaccines may induce serious complications, have the least potential to induce trained immunity and can be included into the recipient’s genome. The low frequency of influenza cases in the current epidemic season serves as an of interference between SARS-Cov-2 and influenza viruses. In epidemic seasons after the Covid-19 pandemic coronaviruses may dominate amongst viruses inducing acute respiratory viruses diseases. It is likely that the decline of the Covid-19 case count (in December-January) in Russia is determined by the heterologous collective immunity formed earlier.
IMPORTANCE OF THE SCHOOL / HEALTH PROFESSIONAL RELATIONSHIP IN THE DEVELOPMENT OF USER CHILDREN AT THE INFANTO-JUVENILE PSYCHOSOCIAL CARE CENTER OF CAMPO GRANDE, MS - BRAZIL
Authors: Silva Milene Bartolomei , Polegato Camila Bartolomei Silva , Pereira Sabrina Terra
Published: March 2021

Children with severe mental disorders or dependent on psychoactive substances tend to suffer several challenges, including their learning. This reality is present in the lives of patients at the Children's Psychosocial Care Center in the city of Campo Grande-MS, where they are daily accompanied by a team of qualified professionals in order to help in their recovery. Among them, there is the role of the teacher who will provide methodologies so that the student does not suffer consequences in his development, at the same time that he can provide his recovery. Thus, the objective of the undergraduate thesis is to verify how the Centro de Atenção Psicossocial Infantojuvenil (CAPSij) assists child users together with the role of the regular school for the child's biopsychosocial development, and of how this partnership between school and health professionals takes place with the intermediation of the patients' families. This study will use a quantitative-qualitative and exploratory approach with children in different age groups and psychosocial situations, together with the professionals involved in the Education and Health agencies in the municipality of Campo Grande, Mato Grosso do Sul. The field research took place at the time of the pandemic due to Covid-19, therefore, all data collection was in medical records of CAPSij, with health professionals who care for children in the Service Centers and with the teachers of these children from the Regular School through online interviews, respecting the social isolation and the guidelines of the World Health Organization (WHO), with the objective of collecting the data that respond to the objective of this research and to verify how the relation between the education and health agencies occurs, with its teaching and learning process that, due to psychosocial diseases, end up suffering with difficulties in their learnings.
Transversal Diagnosis of the Panorama of Professional Education: A Case Study of the City of Itaporã – Mato Grosso do Sul
Authors: Almeida Castro Nelma Lina , Carvalho Sandra Martins de Brito , Paula Pereira Cristina , De Almeida Maria Neide , De Almeida Patricia Coelho , Rachel Arguello Leandro , Dorsa Antonio Carlos , Kubalaki Onaka Patricia , Almeida Castro Luis Henrique
Published: March 2021

This case study aims to identify the demand for professional education courses in the city of Itaporã, in the state of Mato Grosso do Sul, in the year 2020, offering a cross-cutting diagnosis of this educational panorama; for this purpose, the technique of guided interview in loco was implemented with the action coordinating agents designated by the municipal administration. All those involved were aware of their free and voluntary collaboration. During the entire collection phase, the information was recorded through a free association chart which, later revised, gave basis to the identification that in the disclosure phase there is no time to contact the possible students taking into account that, besides the districts, the municipality aggregates a vast rural region. In addition, the fact that the course is offered only at night, ends up discouraging the participation of some potential students who, despite showing interest, need to pay attention to their labor routines. It is concluded that a greater concern is needed to create a database of course graduates in order to establish a periodic sense capable of identifying professional life after the course, in addition to profiling the demand for skilled labor in order to detect which training is important at the moment.
development of a theoretical-practical model for the identification of teaching competencies in Brazilian public innovative universities
Authors: Costa Rejane , Ribas Ulbricht Vânia , Muck Kátia
Published: March 2021

This investigation aims to categorize and identify the general teaching competencies that professors who work in a public innovative Brazilian university should develop. It employs the Delphi Panel method, which allows a consensus of opinions to be reached by a group of experts. This study had eight expert participants from different fields of study. They engaged answering five rounds of instrument, that were sent by email to them. After analyzing the competencies, the experts suggested agglutination between some categories and some eliminations. As a result, the competences were summarized in six categories: Digital, Internalized, Externalized, Teaching Knowledge, Technical and Innovative. This research will serve as theoretical support for the construction and elaboration of a theoretical-practical model for the identification of teaching competencies to work in Brazilian public innovative universities.
Self-regulation and Self-identity Changes among Iranian EFL Learners
Authors: Estehmami Anahita , Ghonsooly Behzad , Royaei Nahid
Published: March 2021

The present study aims to investigate the probable association between self-regulated strategies and self-identity changes among Iranian EFL learners. To achieve this purpose, 80 EFL students were selected according to convenience sampling from different language institutes in Mashhad. They were requested to complete the ' Motivated Strategies for Learning Questionnaires' (MSLQ) and 'Self-identity Changes' questionnaires. The findings yielded via correlation supported the theoretical expectation of a linkage between self-regulation and self-identity changes. The result revealed that there is a significant relationship between teachers' self-regulation high scores and self-confidence changes. Subsequent data from step-wise regression indicated that among sub-components of self-regulation, regulation, efficacy, and intrinsic value are the best predictors of learners' self-confidence changes. The conclusions and implications of the research are further discussed with reference to earlier finding.
FACTORS THAT CONTRIBUTE TO THE SUCCESS OF THE BRAND IN THE INTERNATIONAL MARKET
Authors: LIMA DO NASCIMENTO ROSA LEILA , LIMA MARTINS JÚNIOR JOÃO AMAURY , ALMEIDA PAIXÃO ANA ELEONORA , MOTA DE SOUZA DERBI , DE OLIVEIRA SANTOS KLEBER , BISPO DOS SANTOS OBDERAN
Published: March 2021

The internationalization process is defined as a gradual and constant system of involvement in the company’s negotiations with countries outside its origin borders. Therefore, it is a constant process that takes place in several stages and that can considerably increase the gains obtained from the company’s operations regardless of its size. In this article, the objective was to analyze the factors that contribute to the establishment of national brands in the international market. For this purpose, the methodology adopted was a literary research involving a bibliographical survey. It was concluded that for the brand’s internationalization process to be successful, the company must adopt a correct international market entry strategy, because this is considered an important step that can leverage the company in the future. It was observed that the internationalization is seen as a form of continuous learning in face of the competitions that exist in the international arena, something that involves time and risk.
Successful retreatment of HCV relapse patient with 4 weeks long sofsobuvir, ribavirin, and daclatasvir combination: Case Series
Authors: Saleem Komal , Ali Amjad , Rafique Shazia , Rani Noshaba , Wahid Braira
Published: March 2021

Hepatitis-C virus (HCV) is an enveloped RNA virus that currently infects more than 180 million people, worldwide. Interferon therapy was previously used as a standard therapy for HCV. Now it has been replaced with an interferon-free therapy or the direct acting antiviral (DAA) drug therapy. Although the DAA drug therapy is a potent strategy which has an excellent efficacy against the HCV infection with a majority of patients achieving sustained virological response (SVR), we report here three patients who experienced relapse after a 6-month long DAA drug therapy. The patients experienced relapse after receiving sofosbuvir (400mg) and ribavirin for 6 months. All three patients were later successfully treated with sofosbuvir, ribavirin, and daclatasvir combination. The current study highlights that the retreatment combination of sofosbuvir, ribavirin, and daclatasvir is more efficacious in the Pakistani population where practitioners are still using sofosbuvir and ribavirin.
Influence of sowing dates and methods of weed control on the growth, development and productivity of sunflower in direct seeding technology
Authors: Dridiger Viktor , Gorshkova Natal'ya
Published: March 2021

Abstract. When cultivating sunflower using direct seeding technology, its yield largely depends on the time of sowing and the effectiveness of weed control. The purpose of the research is to study the influence of sowing dates and methods of weed control on the growth, development and productivity of sunflower cultivated using direct seeding technology in the zone of unstable moisture in the Stavropol territory. Methods. Field studies were conducted in the experimental field of the North Caucasus Federal research center (zone of unstable moisture of the Stavropol territory) in 2018–2019, where the objects of research were sunflower crops on April 5–10, April 25–30 and May 15–20, cultivated using direct seeding technology with herbicides according to the following scheme: without the use of herbicides (control), spraying of weeds with a continuous herbicide from the group of glyphosates 5–7 days before sowing sunflower (glyphosate), glyphosate + soil herbicide, which was sprayed on plots after sowing the crop, and glyphosate + herbicide Euro-Lightning, used in the phase of 3–4 pairs of real sunflower leaves. Results. It was found that the transfer of sunflower sowing dates from April to the second decade of may leads to an increase in field germination of seeds, reducing the negative impact of atmospheric and soil drought during the growing season of the crop, which ensures the formation of a significantly greater vegetative mass of plants compared to the April sowing dates. The highest yield is formed by sunflower when sown in the second decade of May with the pre-sowing application of a continuous herbicide from the group of glyphosates in combination with a soil herbicide (2.45 t/ha) and the same glyphosate with the spraying of crops with Euro-Lightning herbicide in the phase of 3–4 pairs of leaves – 2.41 t/ha. Sowing sunflower in April, as well as the refusal to use herbicides or only pre-sowing spraying of the soil with glyphosate leads to a significant decrease in crop yield.
Dynamics of the macronutrients content in sugar beet plants under the application of microfertilizers
Authors: Semina Svetlana , Zheryakov Evgeniy , Zheryakova Yuliya
Published: March 2021

Abstract. The purpose of the current scientific paper is to reveal the effectiveness of foliar treatment with various types of complex fertilizers with microelements in chelated form on the dynamics of nitrogen, phosphorus and potassium in the leaves and roots of sugar beet plants. The novelty lies in the fact that for the first time in the forest-steppe conditions of the Middle Volga region, the authors carried out the research towards the effect of liquid microelement fertilizers on the content of macronutrients in sugar beet plants. Methods. The records and observations were organized according to the generally accepted methods. Results. It was found that 10 days after the first foliar treatment, the nitrogen content in the leaves increased by 0.36–1.08 %. However, a decrease in the accumulation of phosphorus and potassium was noted. In root crops during this period, the nitrogen content decreased by 0.32–0.45 %. There is a tendency towards a decrease in the concentration of phosphorus and potassium in comparison with its content before foliar treatment. Determination of the content of macronutrients 10 days after the second treatment showed that after foliar treatment of plants with “POLIDON Amino Tsink” and “POLIDON Bor”, the nitrogen content in the leaves increased by 0.82–0.88 %. In the same variants, a tendency for an increase in the phosphorus content was noted, but for all variants of the experiment, a decrease in the intake of potassium in the leaves of sugar beets was obvious. It was revealed that the nitrogen content in the leaves increased by 0.07 % after the introduction of boric and zinc-containing micronutrients 20 days before harvesting. With the use of microelement fertilizers, a tendency to an increase in the phosphorus content in the leaves was significant. In root crops, in all variants with microelements, an increase in nitrogen was observed. In the phosphorus content, no significant differences were found regardless of preparation type; a decrease in potassium was noted. The highest yield of root plants was obtained with three-fold foliar treatment of crops with “POLIDON Bor” and exceeded the control by 11.1 %.