bluuebunny/crossref_metadata_2025 huggingface dataset:
Understanding Capital Accounting Practices by Laundry Entrepreneurs Based on Local Wisdom Values
Authors: Thalib Mohamad Anwar , Suaib Rafka , Lawani Nur Laila , Aldi Moh.
Published: June 2024

Purpose: This study aims to understand capital accounting practices of laundry entrepreneurs based on local wisdom values.
Methodology/Approach: This study uses an Islamic paradigm with an Islamic ethno-methodology approach. There are five data analysis stages: charity, knowledge, faith, revealed information, and ihsan. This study uses a qualitative method. There were two types of data collection: structured interviews and passive participant observations. Informants were selected using a type of informant determination in the form of purposive sampling.
Results/findings: The research results show two capital accounting practices implemented by laundry entrepreneurs: the source of capital that comes from side business income, and the method of recording capital accounting in memory. These two capital accounting practices depend on the value of mutual help, which is reflected in establishing a laundry business to help the family economy. The elders often advise the value of helping each other in the household through the expression “delo tombowata lo tabu wawu labiya.” This expression contains the meaning of a peaceful household life.
Limitations: The limitation of this study is that research informants who only gathered information from laundry owners did not include information sourced from customers of the laundry business.
Contribution: This research presents the concept of accounting practices by laundry entrepreneurs based on local cultural values, namely mutual help between husbands and wives.
AKTYVUMO IR DĖMESIO SUTRIKIMO VĖLYVOJOJE PAAUGLYSTĖJE DIAGNOSTIKOS YPATUMAI. KLINIKINIS ATVEJIS
Authors: Misiulytė Toma
Published: June 2024

Aktyvumo ir dėmesio sutrikimas (ADS) – tai neurolo­ginis sutrikimas, kuriam būdingas sutrikęs dėmesys, per didelis aktyvumas bei impulsyvumas. Šiame straipsnyje nagrinėjami aktyvumo ir dėmesio sutrikimo diagnostikos ypatumai vėlyvojoje paauglystėje. Nurodomi veiksniai, dėl kurių gali būti sunku atpažinti ADS šiame amžiaus tarpsnyje. Aptariamas diagnostinių metodikų stygius Lietuvoje.

Pristatomas 17 m. jaunuolio klinikinis atvejis, kuris ilius­truoja vėlyvojoje paauglystėje pasireiškiančius ADS simptomus. Paciento nusiskundimai: sunku susikaupti, ilgiau išlaikyti dėmesį. Jį vargina motorinis aktyvumas, miego bei fizinio aktyvumo stoka. Į specialistus krei­piasi pirmą kartą.

Siekdami nustatyti sutrikimą, paciento būklę vertino keli specialistai. ADS diagnozė buvo patvirtinta. Atlikus dife­rencinės diagnostikos analizę, pateikti vertinimui svarbūs veiksniai. Straipsnyje pristatytas klinikinis atvejis gali būti naudingas gydytojams ir kitiems sveikatos priežiūros specialistams, vertinantiems ir diagnozuojantiems ADS vėlyvojoje paauglystėje.
Assessment of Anti-arthritis Efficacy of Moringa oleifera: In-silico Molecular Docking
Authors: Pandey Atul Kumar , Malik Jitender K , Singh Gyan , Siroliya Vinay
Published: June 2024

Background: The severity of rheumatoid arthritis (RA), a chronic, inflammatory, and systemic autoimmune disease, on a patient's joints varies. Age, gender, genetics, and environmental exposure (tobacco use, exposure to air pollution, and occupational exposure) are risk factors. If left untreated, Felty syndrome can develop into a variety of consequences, including rheumatoid vasculitis, persistent joint damage needing arthroplasty, and Felty syndrome necessitating splenectomy. The objectives of treatment for RA are to alleviate discomfort and prevent/slow additional damage because there is no known cure. Munga, also known as Moringa oleifera Lam., is one of the most significant plants grown extensively in India. This plant, Moringa oleifera Lam, is used extensively as a dietary supplement and has valuable pharmacological properties including anti-asthmatic, anti-diabetic, hepatoprotective, anti-inflammatory, anti-cancer, antimicrobial, anti-oxidant, cardiovascular, anti-ulcer, CNS activity, anti-allergic, wound healing, analgesic, and antipyretic action. This plant has great therapeutic properties in every area. It is a good source of milk protein, vitamin A, and vitamin C. Alkaloids, protein, quinine, saponins, flavonoids, tannin, steroids, glycosides, fixed oil, and lipids are only a few examples of the several active phytoconstituents that are present. Aim and Objective: The goal of the current study was to evaluate M. oleifera leaf anti-arthritic efficacy. Method: In -silico molecular modelling studies for assessment of anti-arthritic potential of M.oleifera leaf was designed taking quercetin and niazirinin as lead molecule found in the ethanolic leaf extract(as per literature survey) against HK-2 protein. A grid-based docking strategy was used to determine the binding using the Auto Dock software. Merck Molecular Force Field was used to build the 2D structures of compounds, convert them to 3D, and then energetically reduce them up to arms gradient of 0.01. (MMFF). Result: The finding of molecular modelling of lead molecule with HK-2 protein showed that both the selected molecules have good affinity towards HK-2 protein but quercetin found to be high binding affinity. The binding energy of quercetin and niazirinin against HK-2 protein was found to be -6.66 & -5.58 Kcalmol-1 respectively.
Evaluation of Peel Bond Strength between Heat Cured Acrylic Based Denture Soft Lining Material and Heat Polymerized Acrylic after Different Acrylic Surface Treatment Methods
Authors: Ahmed Ali Saad , Kamil Saif Saad , Hammed Safwan Abdul- , Ahmed Rusul Saad
Published: June 2024

Background: In dentures that involve soft liner materials, it is important that the attachment to soft liners is preserved for an extended period to ensure maintenance of prosthetic parts and patient satisfaction. Debonding can be prevented by a variety of acrylic surface treatments to enhance the connection between the different materials. Methods: 30 specimens were fabricated (30 soft-liner specimens bonded to 30 acrylic specimens). All specimens were 75mm x 10mm x 2mm in dimensions. After bonding, 10 specimens were categorized into each group according to each surface treatment. Acrylic bonding surfaces were treated according to each method and a primer was then applied. Soft liner was mixed and poured inside the matrix part of the mold with acrylic specimens. Peel strength test was measured using a universal testing machine. Specimens were categorized according to failure mode into cohesive, adhesive, and mixed failures. Results: homogeneity of variance and One way ANOVA were utilized. Ethyl acetate group with had the highest peel strength values (4.5138) followed by sandblasting group (3.4633) and silicon carbide paper group (2.9082) respectively. Conclusions: Acrylic specimens treated by ethyl acetate solution, sandblasting, and Silicon carbide paper before bonding to soft liners can provide significant increase in peel strength values which can improve the maintenance of prosthetic parts.
Theorizing "Exercise Book" Through the Perspectives of Three Translation Theorists Jakobson, Derrida and Benjamin
Authors: Liza Sharmin , Oysharja1 Lutfun Naher Mahmud
Published: June 2024

A noble translator uncovers a text for the target language readers. An amateur translator, on the other hand, may destroy the prospect, beauty, and liveliness of the text. Therefore, while translating a text, a translator has to turn on his/her utmost possible creative aptitude along with a fanciful imagination of linguistic ability in context. The text “Exercise Book” is a short story, the translation of “Khata”, extracted from the collection of Rabindranath Tagore's short stories titled Rabindranath Tagore: Selected Short Stories, translated by William Radice. This analysis attempts to explore the emotional narrative and discovers if it interprets the subjectivity of Uma’s feelings and thoughts depicted in the short story “Khata” relatively. In addition, this paper is an exertion to understand and scrutinize which category of the translation does this story follow, while translating a text whether it is a sense-for-sense translation or word-for-word translation and whether it is a literary art form or not. For theorizing the translated short story three translation theories by Jakobson, Derrida and Benjamin have been reconnoitered in the paper. Keywords: Translator, creative, sense-for-sense, word-for-word, art, translation
Harmonizing Fine-tuned Llama 2 for Content Generation with Stable Diffusion for Image Synthesis in Article Creation
Authors: P. Shenbagam , K S. Thrisha Vaishnavi , S. Hariprakassh , K. Abhirami , B. Abiram , K S. Rakesh Nandhaa
Published: June 2024

The research explores the integration of generative AI in multimedia content production using a fine-tuned Llama 2 model for text generation and the Stable Diffusion algorithm for image synthesis. The research analyses the fine-tuned Llama 2-7b-chat model's adaptability to specific content generation contexts, enhanced by a unique dataset and QLoRa, a Quantized Low-Rank Adaptation for parameter-efficient fine-tuning, achieving significant reductions in training loss and nuanced quality in the generated content. Notably, the model's evaluation yielded an impressive perplexity score of 1.49, indicating advanced predictive performance. Additionally, stable diffusion's ability to transform textual descriptions into intricate images, highlighting its potential in AI-mediated content creation is demonstrated. The experiments and qualitative analyses reveal improvements in efficiency and creativity, emphasizing the collaborative potential of these models to revolutionize multidisciplinary content generation. The research underscores the transformative impact of fine-tuned generative models on content creation and offers insights into the broader implications for future AI research, while acknowledging the critical need for ethical considerations in the deployment of such technologies.
Hubungan Perilaku Ibu Nifas Dengan Penyembuhan Luka Pada Perineum di Puskesmas Krembangan Selatan Kota Surabaya
Authors: Dwi Lia Rahmawati  , Sherly Jeniawaty  , Fitria Nurwulansari  , Sri Utami
Published: June 2024

Robekan perineum terjadi hampir pada semua persalinan sehingga diperlukan perawatan yang intensif untuk mencegah infeksi. Meskipun bukan penyebab langsung, infeksi jalan lahir yang tidak di tangani dengan benar akan menyebabkan komplikasi sehingga terjadi kematian ibu. Profil Kesehatan Indonesia 2021 menyebutkan jumlah kematian ibu karena infeksi yaitu sebanyak 207 kasus. Tujuan penelitian ini adalah untuk mengetahui hubungan perilaku ibu nifas dengan penyembuhan luka pada perineum di Wilayah Puskesmas Krembangan Selatan Kota Surabaya. Desain penelitian ini menggunakan survei analitik dengan rancangan cross sectional. Jumlah sampel penelitian adalah 39 ibu hamil yang dipilih menggunakan non probability sampling yaitu purposive sampling. Variabel independen dalam penelitian ini adalah pengetahuan, sikap, dan tindakan, sedangkan variabel dependen  adalah penyembuhan luka pada perineum. Tehnik pengumpulan data secara primer dengan kuiosioner dan lembar penilaian. Analisis yang digunakan dalam menguji penelitian ini adalah chi square dan fisher exact.Hasil penelitian ini menunjukan bahwa terdapat hubungan pengetahuan dengan penyembuhan luka perineum dengan p-value 0,047 < α (0,05), terdapat hubungan sikap dengan penyembuhan luka perineum dengan p-value 0,033 < α (0,05), dan terdapat hubungan tindakan dengan penyembuhan luka perineum dengan nilai p-value 0,019< α (0,05). Penyembuhan luka pada perineum berhubungan dengan pengetahuan, sikap, dan tindakan ibu selama masa nifas. Oleh karena itu upaya yang dapat dilakukan untuk meningkatkan pelayanan kesehatan terutama pada ibu nifas yang mengalami luka perineum adalah dengan memberikan penyuluhan serta asuhan tentang cara menjaga dan merawat luka perineum sampai luka perineum sembuh dan membaik.
Hubungan Penggunaan Gadget Dengan Interaksi Sosial Anak Usia 4-6 Tahun Di KB TKIT Al Hikmah Surabaya
Authors: Setya Rohmah Aldita Hajar , Astuti Setiyani  , Eka Kusuma Wardani Novita , Sukesi
Published: June 2024

Usia dini merupakan periode masa pertumbuhan dan perkembangan, pada masa tersebut semua potensi pada anak akan berkembang dengan pesat. Stimulasi lingkungan sangat penting untuk memicu perkembangan otak. Dilihat dari kenyataannya orang tua pada zaman sekarang banyak yang memberikan gadget pada anaknya. Penelitian ini bertujuan untuk mengetahui hubungan penggunaan gadget dengan interaksi sosial anak usia 4-6 tahun di KB TKIT Al Hikmah Surabaya. 
Jenis penelitian ini adalah kuantitatif menggunakan desain CrossSectional. Variabel independen adalah penggunaan gadget dan variabel dependen adalah interaksi sosial. Populasi penelitian ini sebanyak 156 orang tua. Sampel ditentukan dengan metode Purposive Sampling sebanyak 112 responden. Instrumen yang digunakan menggunakan lembar kuesioner yang diuji validitas dan reliabilitas. Pengolahan data menggunakan analisis univariat dan analisis bivariat dengan uji statistik Spearman Rank.
Penelitian menunjukkan Penggunaan Gadget memiliki hubungan dengan Interaksi Sosial Anak. Analisis Spearman Rank dengan p-Value = 0,005. Dengan taraf signifikan p <0,05 dengan nilai r hitung = -0,263 H1 diterima, artinya ada hubungan antara penggunaan gadget dengan interaksi sosial anak usia 4-6 tahun di KB TKIT Al Hikmah Surabaya. Hasil uji statistik Spearman Rank bahwa r hitung = -0,263 yang berarti hubungan tidak searah, semakin tinggi penggunaan gadget semakin menurun interaksi sosial pada anak. Kesimpulan dari penelitian ini adalah terdapat Hubungan Penggunaan Gadget dengan Interaksi Sosial Anak Usia 4-6 Tahun di KB TKIT Al Hikmah Surabaya.
PERCEPÇÕES E DESAFIOS NA MIGRAÇÃO DE MULHERES BRASILEIRAS DO SUL DE MINAS GERAIS PARA A FLÓRIDA
Authors: Goncalves Nara Fernanda , Lopes Salgado Ribeiro Suzana , Maria Andrade Brisola Elisa
Published: June 2024

O presente artigo tem como problema de pesquisa investigar quais as percepções no processo migratório de mulheres mineiras para os Estados Unidos, abordando quais os desafios que elas enfrentam, o que motivam a imigrar para os Estados Unidos, especialmente para a região da Flórida. A pesquisa teve como objetivo compreender as motivações e as experiências de mulheres mineiras no processo de deslocamento. O instrumento foi a realização de entrevistas com dez mulheres que migraram do sul de Minas Gerais-BR para a Flórida-EUA. Os dados coletados foram analisados pela técnica de triangulação, em qual articulação como narrativas, o contexto e diálogo com autores que estudam as temáticas emergentes das narrativas. Como resultados, percebe-se que as mulheres migram para os Estados Unidos em busca de melhores condições culturais, financeiras e sociais. Que apesar das dificuldades com a língua inglesa e de adaptação à nova cultura, elas não têm interesse em retornar para o Brasil. Atualmente o perfil da mulher imigrante é heterogêneo, vindo de diversas classes sociais e não mais relacionado à figura masculina como relatado no início do século passado.
International Human Rights Law: Enforcement Mechanisms and Challenges in a Globalized World
Authors: Biswa Astika
Published: June 2024

A glimmer of hope in the fight for the promotion and protection of human dignity and basic human rights is international human rights law (IHRL). individuals worldwide. Yet, its efficacy depends heavily on the robustness of enforcement mechanisms and their adaptation to the complexities of a globalized world. This paper explores the various enforcement mechanisms within IHRL, ranging from international treaties and conventions to regional human rights bodies and domestic legal systems. It delves into the challenges facing these mechanisms, including issues of jurisdiction, state sovereignty, political will, and resource constraints. Moreover, it examines how globalization, with its interconnectedness and transnational nature, both facilitates and complicates the enforcement of human rights norms. The paper concludes by highlighting the need for enhanced cooperation among states, international organizations, civil society actors, and other stakeholders to overcome these challenges and ensure the effective enforcement of IHRL in a rapidly evolving global landscape.
Characteristics of the mental health of employees of healthcare facilities in the conditions of war
Authors: Lekhan Valeria M. , Borvinko Elvira V. , Zaitsev Vyacheslav V. , Zaslavskyi Daniel D.
Published: June 2024

Aim: To study the state of mental health of staff of healthcare facilities (HCFs) of different categories (managers, doctors, nurses) 2 years after the beginning of the Russian invasion of Ukraine.
Materials and Methods: The study, using valid psycho-diagnostic methods, was conducted in 3 stages: studying the frequency of mental states, Mental Health Continuum, and occupational self-efficacy. Using descriptive and analytical statistics, we analyzed the results obtained from 114 respondents.
Results: It was found that in the majority of the study group, regardless of the position held (manager, doctor, nurse), the levels of anxiety, frustration, aggressiveness, and rigidity were low (64.0%-50.9% of respondents); flourishing and high development of occupational self-efficacy were recorded in 59.6% and 61.0%, staff of HCFs respectively. A small proportion of specialists (10.5%-4.4%) revealed a high level of manifestation of mental states; languishing and a low level of professional self-efficacy were practically absent. In other study participants, all indicators were at the borderline level.
Conclusions: Almost 2 years of functioning in the context of the war has led to the development of a certain adaptation and resilience in all categories of healthcare employees, which allows them to fulfill their professional duties. At the same time, there is a significant number of healthcare professionals who have moderate and high levels of mental stress, and problems with mental health stability, which requires systemic decisions to be made at the sectoral level to ensure the mental health of staff of healthcare facilities.
Non-communicable diseases and their risk factors in Ukraine: analysis of the global burden of disease 2019 study
Authors: Orlova Nataliia M. , Kovtun Gavrilo I. , Holovchanska-Pushkar Svitlana E. , Pylypchuk Valentyna L. , Palamar Inna V. , Tkachenko Olena V. , Zadorozhniuk Oksana V.
Published: June 2024

Aim: To analyse the burden and risk factors of Non-Communicable diseases (NCDs) in Ukraine to determine the ways to prevent them.
Materials and Methods: Using a statistical method, NCDs DALYs (Disability-Adjusted Life Years) in Ukraine were analyzed in dynamics for 1990-2019 and in comparison, with European and EU countries based on the data from “Global Burden of Disease, 2019” research.
Results: The burden of NCDs in Ukraine is 1.5 time higher than in European and EU countries. The most negative dynamic trends and significant differences between indicators in Ukraine and EU countries (with an excess of 2 or more times) were identified for DALYs due to cardiovascular diseases, digestive diseases and substance use disorders. In Ukraine the burden of NCDs can be reduced on 25.9% by normalization of systolic blood pressure, on 21.2% by optimizing diet, on18.5% by quitting smoking, on 17.6% by lowering LDL cholesterol, on 16.5% by normalizing body weight and on 9.2% by quitting alcohol abuse.
Conclusions: Ukraine should develop and implement a modern system for monitoring and assessing the NCDs burden and their risk factors; strengthen the capacity of public health institutions and their ability to attract communities to implement interventions to control NCDs modified risk factors, increase awarnes and the population’s responsible attitude towards their health; strengthen the ability and motivate primary health care to provide quality primary prevention, screening and timely diagnosis and treatment of chronic NCDs.
Spiritual health under the wartime: existential aspects
Authors: Vasylieva Iryna V. , Shevchenko Serhii L. , Hololobova Kateryna O. , Laputko Anna V. , Kiriienko Serhii V.
Published: June 2024

Aim: To study the spiritual health in existential dimensions, as well as the meaning, value, and emotional components of spiritual health of Ukrainians under the wartime.
Materials and Methods: The theoretical and methodological framework of the paper is represented by the works of scholars in classical existentialism, contemporary philosophers, psychologists, medical psychologists, theologians, sociologists, etc. The complex nature of the issue necessitated the use of interdisciplinary approaches, philosophical, general scientific and special sociological methods of gathering, processing and analyzing information.
Results: The article analyzes the perception of spirituality and spiritual health related to mental and social aspects in the philosophy of classical existentialism and existential-humanistic psychology. The paper justifies the heuristic potential of these approaches for maintaining spiritual health of Ukrainians, which is based on holistic approaches to human beings and their spiritual frames. The article represents the results of sociological research by the Institute of Sociology of the National Academy of Sciences of Ukraine, the Scientific Research Institute of Social and Economic Development of the City, and a survey of the PhD students of the Bogomolets National Medical University (N=103) made by the authors, representing the results of statistical treatment of the spiritual health characteristics: emotional, value and meaning components.
Conclusions: The study has shown that the deterioration of mental health indicators of Ukrainians during the war is not accompanied by corresponding negative trends in their spiritual health. However, further research on this issue is necessary, including studies among respondents from other age groups (faculty, staff of the Bogomolets National Medical University).
A comprehensive analysis of anthropometric indicators in preschool children suffering from recurrent respiratory infections
Authors: Voloshyn Oleksandr M. , Marushko Yurii V. , Hyshchak Tetiana V. , Savchenko Iryna I.
Published: June 2024

Aim: To determine the state of relationship between anthropometric indicators and susceptibility to recurrent respiratory infections in preschool children.
Materials and Methods: A total of 143 children (73 boys and 70 girls) aged 12-59 months, undergoing inpatient treatment on acute respiratory infection, were involved in the clinical study. The number of acute respiratory infection episodes during a previous year of their lives was taken into account. Besides, the basic indicators of physical development were assessed in the children, including: 1) body weight; 2) body length; 3) chest circumference; 4) body mass index; 5) body surface area; 6) Vervek’s index.
Results: Cross-tabulation and rank correlation analysis did not demonstrate any interdependence between the susceptibility of the children examined to recurrent respiratory infections and their anthropometric indicators. Simultaneously, linear regression analysis showed that in the children aged 12-23 months, resistance index depended on their age and body length. The relative importance of the combined effect of the two above-mentioned indicators among all other potential risk factors for recurrent respiratory infections was 32.2%.
Conclusions: The detailed analysis of the findings outlined the methodological basis for further studies of the association between the incidence of acute respiratory infections in preschool children and their physical development. Multivariate statistical calculations of various risk factors for recurrent respiratory infections, including abnormal anthropometric indicators, are likely to increase the informational value of subsequent examinations.
Peculiarities of local immunity in dry eye disease on the background of hormonal dysfunction
Authors: Zhaboedov Dmytriy G. , Skrypnyk Rimma L. , Tykhonchuk Nataliia A. , Zadorozhna Alla I. , Skrypnychenko Inna D. , Lekhnitska Svitlana I. , Sakhanda Ivanna V.
Published: June 2024

Aim: to determine the state of local immunity in DED on the background of hormonal dysfunction.
Materials and Methods: Of 32 women, 17 patients with diagnosed SM and 15 women of the control group were examined. The Ocular Surface Disease Index and the state of local immunity were defined by determining Ig As in lacrimal fluid (LF) by radial immunodiffusion in Mancini agar.
Results: During the OSDI questionnaire, a mild degree of DED was detected in 21 (65.6%) women, and an average degree was observed in 11 (34.4%) patients with SM. On average, OSDI was 34.54 ±2.01. As a result of studies of the state of local immunity in patients with SM, a tendency to increase Ig As was noted, compared with the control group. An increase in Ig As in the lacrimal fluid in patients with SM to 0.34 ±0.09 g/l was found, compared with the control group (0.24 ±0.03 g/l).
Conclusions: Using the OSDI questionnaire, the presence of DED was detected in women with SM, mainly mild and moderate degree. The obtained results of the state of local immunity indicate in favor of a nonspecific inflammatory process, accompanied by a decrease in local immune protection and leading to further changes in the ocular surface.
Treatment of patients with crowding of the anterior group of teeth by circumferential supracrestal fiberotomy
Authors: Zhachko Nataliia I. , Skrypnyk Iryna L. , Golod Romana O. , Zhachko Maksym S. , Nespriadko-Monborgne Tamara S.
Published: June 2024

Aim: To evaluate the effectiveness of the use of circumferential supracrestal fiberotomy in the treatment of tortoanomalies to improve the effectiveness of treatment, prevent recurrence and increase the stability of the achieved result.
Materials and Methods: Our study consists in determining the effectiveness of the use of methods that prevent the recurrence of tortoanomalies – circumferential supracrestal fiberotomy (CSF) in patients over the age of 16 years and the effect of CSF on the gingival junction in the treatment of tortoanomalіes with fixed orthodontic multibonding equipment.
Results: The high level of stability of results proves expediency operations circumferential supracrestal fiberotomy and papilla splitting at orthodontic treatment of frontal teeth density at patients older 16 years and for increasing stability of results of treatment by prevention of relapse tortoanomalies. Efficiency of the offered ways of treatment is proved clinically and anthropometrically on the early and remote terms of supervision (1, 6, 12 months).
Conclusions: The high level of stability of results proves expediency operations circumferential supracrestal fiberotomy and papilla splitting at orthodontic treatment of frontal teeth density at patients older 16 years and for increasing stability of results of treatment by prevention of relapse tortoanomalies. Efficiency of the offered ways of treatment is proved clinically and anthropometrically on the early and remote terms of supervision (1, 6, 12 months).
Cost-effectiveness of dialysis and kidney transplantation to treat end-stage renal disease in Ukraine
Authors: Hryshchuk Serhii M. , Parii Valentin D.
Published: June 2024

Aim: To determine the economic feasibility of using kidney transplantation compared to hemodialysis in end-stage renal disease in the long term in countries with a low and medium level of economic development using the example of Ukraine.
Materials and Methods: The cost effectiveness analysis method was used. Conducted Markov modeling and comparison of the consequences of kidney transplantation and hemodialysis in terms of treatment costs and the number of added years of life for a cohort of 1,675 patients were carried out. The incremental cost-effectiveness ratio is defined.
Results: Based on the results of modeling, it was determined that among 1,675 patients with end-stage kidney disease in Ukraine, 1,248 (74.5%) will remain alive after 10 years of treatment when kidney transplantation technology is used. The highest costs will be in the first year ($25,864), and in subsequent years - about $5,769. With the use of hemodialysis technology, only 728 patients (43.5%) will be alive after 10 years, the cost of treating one patient per year is $11,351. The use of kidney transplantation adds 3191 years of quality life for 1675 patients compared with hemodialysis (1.9 years per patient).
Conclusions: Kidney transplantation is an economically feasible technology for Ukraine, as the incremental cost-effectiveness ratio is $4694, which is 1.04 times higher than Ukraine’s GDP per capita. The results of the study allow us to recommend that decision-makers in countries with a low and medium level of economic development give priority in financing to renal transplantation.
Values of academic integrity in higher medical education
Authors: Vlasenko Oleg М. , Kucherenko Inna , Turchyn Maryna Ya. , Nechushkina Olha , Kobrzhytskyi Viacheslav , Hrytsenko Oksana A.
Published: June 2024

Aim: The aim is to identify features of theoretical and empirical research of academic integrity as characteristics of the educational environment of medical higher education institution (hereinafter – HEI).
Materials and Methods: A complex of general scientific methods: logical-analytical, dialectical, theoretical-logical, comparative analysis, formalization and generalization, as well as quantitative sociological methods for collecting, processing and analyzing information. The object of the pilot empirical study were domestic medical students of full-time education at the Bogomolets NMU (N=472) and scientific and pedagogical staff who provide teaching of fundamental, specialized and socio-humanitarian disciplines at the university (N=153).
Results: The values of academic integrity are the moral guideline that reveals the latest ethical demands of society and regulates the educational and scientific activities of all participants in the educational process. Opinions on the primary responsibility for compliance with the rules of academic integrity of a student differ between the surveyed scientific and pedagogical staff and students (p=0.000): the vast majority of the surveyed scientific and pedagogical staff tend to evenly divide the responsibility between a teacher and a student, and the majority of students-respondents noted that the student bears the primary responsibility.
Conclusions: Commitment to the principles of integrity motivates both students and teaching staff to act in an academic manner. Therefore, the creation of a methodology for studying the phenomenon of academic integrity in medical higher education institution through the study of attitude of the subjects of educational process to basic values is promising.
Factors associated with female infertility in Ukraine: results a multicenter study
Authors: Salmanov Aidyn G. , Yuzko Oleksandr M. , Tofan Bohdan Yu. , Artyomenko Volodymyr V. , Korniyenko Svitlana M. , Rud Victor O. , Dyndar Olena A. , Kovalyshyn Orusia A. , Nykoniuk Tetiana R. , Nastradina Nataliia M.
Published: June 2024

Aim: To determine the current prevalence of female infertility and characterize and identify risk factors associated with infertility in Ukraine.
Materials and Methods: Multicenter prospective cohort study was conducted from January 2021 to December 2023 in twelve medical centers from nine regions of Ukraine. Definitions of infertility were adapted from the World Health Organization. According to the data collected from questionnaire, participants were divided into infertile and fertile groups and analyzed associated factors.
Results: Among all the 7,618 participants in this study, the prevalence of female infertility was 24.3%. The prevalence of primary infertility was 5.9%, and
the prevalence of secondary infertility was 18.4%. In logistic multivariate regression analyses, female infertility was associated with age of women (p<0.001), age of first sexual intercourse (p<0.001), history of gynecological surgery (p<0.001), marital status (p<0.001), age of marriage (p<0.001), decreased ovarian reserve (DOR) (p=0.006), family history of infertility (p<0.001), history of cervicitis (p=0.007), history of surgical abortion (p<0.001), history of endometritis (p=0.027), bacterial vaginosis (p=0.023), and aerobic vaginitis (< 0.001).
Conclusions: Our data suggest a high prevalence of female infertility in Ukraine. The prevalence of secondary infertility was higher than primary infertility. Age of women, age of first sexual intercourse, history of gynecological surgery, marital status, age of marriage, DOR, family history of infertility, history of cervicitis, history of surgical abortion, history of endometritis, bacterial vaginosis, and aerobic vaginitis were associated with infertility.
Effect of ivabradine on structural and functional changes of myocardium and NT-proBNP levels in patients with stable coronary heart disease after coronary stenting
Authors: Kupnovytska Iryna H. , Romanyshyn Nelia M. , Fitkovska Iryna P. , Gubina Nataliia V. , Krasnopolsky Sergej Z. , Klymenko Vira I. , Kalugina Svitlana M.
Published: June 2024

Aim: To investigate the effect of ivabradine on the hemodynamics and contractility of the myocardium and the features of NT-pro-BNP production in patients with stable ischemic heart disease after endovascular revascularization of the myocardium depending on the number of affected coronary arteries during 12 months of therapy.
Materials and Methods: The object of the study was 120 patients with stable coronary artery disease: angina pectoris of functional class III with heart failure IIA FC III with preserved and moderately reduced ejection fraction of the left ventricle, who underwent coronary artery stenting. The examined patients were randomized according to the number of affected coronary vessels and the method of treatment.
Results: Ivabradine in patients with stable ischemic heart disease after 12 months of therapy had a significant beneficial effect on the structural and functional parameters of the myocardium (contributed to the reverse remodeling of the left ventricle), which did not depend on the number of stented coronary arteries (p<0.05). In patients with stented one coronary artery, all structural and functional indicators of the heart after 12 months of treatment reached the values of practically healthy individuals from the control group. The use of ivabradine in patients with stable ischemic heart disease with heart failure with preserved and intermediate ejection fraction of the left ventricle after coronary stenting made it possible to ensure the correction of a number of clinical and pathogenetic links of the disease, which generally contributed to the improvement of metric and volumetric parameters of the heart.
Conclusions: Ivabradine made it possible to significantly increase the effectiveness of standard therapy, which was manifested by a faster recovery of the geometry and contractility of the left ventricle. Therefore, the use of ivabradine along with standard therapy was appropriate for such a contingent of patients. The management of patients with stable coronary heart disease should combine adequate (surgical and pharmacological) treatment of the underlying disease, further individual medication correction of symptoms and circulatory disorders inherent in coronary heart disease and heart failure.
Health-saving technologies as a need and lifestyle of Ukrainians
Authors: Bilavych Halyna V. , Sultanova Natalia V. , Borys Uliana Z. , Tkachivska Inna М. , Fedchyshyn Nadiya O. , Fedoniuk Larysa Ya. , Savchuk Borys P.
Published: June 2024

Aim: The article analyzes the health-saving technologies of Ukrainians in Eastern Galicia (the end of the XIX century – 1939).
Materials and Methods: In the investigation a number of scientific methods are used: chronological, historical, specific-search, content analysis, providing selection, analysis of the source base, allowing to identify general trends, directions of development, achievements and gaps in the movement for the health of children and adults in Galicia; sources of Ukrainian and Polish authors of different generations in the field of health protection and preservation, physical education and sports, education and upbringing were used, their views and research results were presented.
Conclusions: A component of the health-saving philosophy of Ukrainians (children, youth and adults) of Eastern Galicia in the late XIX – 30s of the XX century was the idea of physical education. Through traveling and camping, playing sports, improving children, youth and adults in places of active recreation (≪dwellings,≫ ≪half-dwellings,≫ ≪cuttings,≫ etc.), the philosophy of health conservation took a leading position in the interwar period of the XX century. The physical education movement had particular successes when a wide circle of Ukrainian youth joined it. There was an original Plast method of physical education of a Ukrainian – physically, spiritually, morally, mentally healthy person, for whom health preservation is a way and philosophy of life, a vital need. All this actualizes the problem of health-oriented public initiatives, which should be creatively used in the current challenges in Ukraine.
Influence of respiratory infections pandemics on the mortality of the population of Ukraine
Authors: Korolenko Viktoriia V. , Mokhort Hennadii A.
Published: June 2024

Aim: To analyze the dynamics and structure of the excess mortality of the population of Ukraine for 76 years (1945-2021).
Materials and Methods: An observational population study was conducted. Epidemiological methods were used, in particular, the method of graphical construction of time series, intensive, extensive indicators and indicators of excess mortality were calculated.
Conclusions: The coronavirus disease pandemic in Ukraine became the largest documented respiratory infection pandemic after 76 years, but did not outweigh the dramatic increase in mortality in the 1990s–2000s, in including death in 1995.
Evaluación de Desempeño e Intención de Mejora en Empleados de Empresas Manufactureras
Authors: Rosales Padilla Nora Veronica , Carlos Ornelas Carmen Estel , Gómez García María Teresa
Published: June 2024

La intención de mejora que precede al comportamiento de mejora de los empleados es un factor primordial para que las empresas que los emplean logren sus objetivos. Este estudio examinó la influencia de dos variables de la Evaluación del Desempeño (ED): la diligencia del supervisor y las reacciones de los subordinados a la reunión de ED. Se incorporaron al análisis 13 variables de control, que incluyeron 7 demográficas y 6 factores relacionados con la evaluación del desempeño, tales como consideración individualizada, relación, apoyo del supervisor, justicia procedimental, precisión de la ED y satisfacción con la ED. Los datos se recopilaron a través de un cuestionario proporcionado por McClendon et al. y se obtuvieron respuestas de 224 empleados de empresas manufactureras automotrices de la ciudad de Aguascalientes. Los coeficientes de confiabilidad del cuestionario fueron altos, indicando una consistencia robusta en las respuestas. Un análisis de regresión múltiple reveló un modelo explicativo del 0.456 de la varianza en la intención de mejora, destacando la contribución significativa de los factores de retroalimentación y diligencia del supervisor, sin la inclusión de las variables de control. En este contexto, la retroalimentación se destacó como el factor clave, sugiriendo que la asignación de recursos organizacionales para la capacitación de supervisores podría generar mayores beneficios en el comportamiento de mejora de los empleados. Estos hallazgos resaltan la importancia de la retroalimentación y la diligencia del supervisor como elementos críticos en el impulso de la intención de mejora entre los empleados.
Statistical abstract: 2023
Authors: Ziesler Pamela , Spalding Claire
Published: June 2024

In the pages that follow, a series of tables and figures display visitor use statistics for calendar year 2023. By documenting visits, hours, and overnight stays across the National Park System, the National Park Service (NPS) Statistical Abstract offers a historical record of visitor use in parks and provides NPS staff and partners with a useful tool for effective management and planning. In 2023, 400 of the 428 National Park System units collected and reported visitor use statistics; the remainder are unable to do so for a variety of reasons such as administration by another agency, non-federal land ownership, or new parks that lack staff and facilities for the management of visitor use statistics.

The responsibility for compiling and summarizing visitor use statistics resides with the Social Science Program in the NPS Natural Resource Stewardship and Science Directorate. The Program relies on the conscientious efforts of NPS field personnel to count, record, and report visitor use. This system of collecting and summarizing monthly visitor use data is combined with continuous review and assessment of park visitor use estimation procedures to promote consistency and accuracy of data. Detailed instructions for the units that collect data, monthly visitation summaries, and reports displaying trends in park visitation are available on the NPS Visitor Use Statistics website (https://irma.nps.gov/Stats/)
Didactic Infrastructure Management and Curriculum Implementation in Public Universities in Northern Uganda
Authors: Bileti Emmanuel Acidri , Ndawula Stephen , Kebirungi Harriet , Rwothumio Joseph
Published: June 2024

This study investigated the levels of curriculum implementation and didactic infrastructure management in public universities in Northern Uganda. It evaluated the influence of didactic infrastructure management on curriculum implementation in public universities in Northern Uganda. It was hypothesised that didactic infrastructure management has no significant relationship with curriculum implementation in public universities in Northern Uganda. The study was guided by a pragmatic worldview and embraced a concurrent mixed-methods research design. The study used a questionnaire to collect quantitative data from 123 respondents. Qualitative data was collected from 26 participants through interviews. Furthermore, eight focus group discussions were conducted. The quantitative data collected was analysed using descriptive statistics, correlation coefficient analysis and multiple linear regression techniques, while thematic analysis techniques were used to analyse qualitative data. The study revealed that, generally, the levels of curriculum implementation were low and didactic infrastructure management was moderate. The study results showed that didactic infrastructure management had a significant influence on curriculum implementation in public universities in Northern Uganda. The null hypothesis that didactic infrastructure management has no significant relationship with curriculum implementation in public universities in Northern Uganda was rejected. The study concluded that didactic infrastructure management is significant for curriculum implementation. Therefore, it was recommended that public universities in Northern Uganda improve the management of their didactic infrastructure, such as libraries, sports facilities, and halls, to further enhance curriculum implementation, especially in areas of preparation for teaching, content delivery, and assessment of learning
EVOLUTION OF APPROACHES TO FORMATION OF THE CONCEPT OF SUSTAINABLE DEVELOPMENT OF THE ENTERPRISE
Authors: Komandrovska Veronika
Published: June 2024

Purpose. The aim of the article is to study the emergence and evolution of the term “sustainable enterprise development”, existing approaches to interpreting its essence in economic literature, and shaping the definition from the author's understanding.

Methodology of research. The method of scientific abstraction, analysis and synthesis was used when studying the evolution of the concepts of sustainable enterprise development – in determining the theoretical and methodological approaches to the essence of the concept of "sustainable enterprise development"; system and integrated approaches – in identifying factors that determine the features of the definition of the term "sustainable enterprise development" for the Economy 5.0.

Findings. The article examines the evolution of approaches to the formation of the concept of sustainable enterprise development under the influence of global challenges and technological progress, increasing demands for responsible and environmentally friendly business conduct. The evolution of the approaches of leading scientists to the interpretation of the concept under study and the substantiation of the author's vision from the standpoint of the Economy 5.0 concept is systematized.

Originality. The definition of the concept of "sustainable enterprise development" is proposed, taking into account the features of the Fourth Industrial Revolution and the transition to the Economy 5.0. It is determined that the sustainable development of an enterprise is a strategic approach to enterprise management that combines innovative technologies and a high level of automation with a responsible society aimed at achieving economic prosperity, social ethics and a balance between economic, environmental, social and cultural aspects, in order to create a viable and resilient business model.

Practical value. The practical value is determined by the possibility of using the results of conducted research by enterprises to form a strategy for sustainable development, taking into account current trends.

Key words: sustainable development, sustainable development concept, Economy 5.0, innovation.
OPEN INNOVATION AS A COMPLEX MECHANISM OF MODERN INNOVATIVE DEVELOPMENT
Authors: Chernyshova Taia
Published: June 2024

Purpose. The aim of the article is to study the regularities of open innovations in the process of modern innovative development and development of a complex model that explains the cause-and-effect mechanism of the development of open innovations in the multiplicity of their manifestation.

Methodology of research. The following research methods were applied to achieve the goal: to identify the essence of the concept of “open innovation” – methods of analysis and synthesis; for the accumulation of disjointed, but causally connected facts, concepts – methods of induction and deduction in their dialectics; for the formulation of theoretical generalizations – the abstract and logical method; for visualization of research results – graphic method; for the definition and classification of approaches to the interpretation of the studied category – the method of systematization.

Findings. The essence of the concept of "open innovation" was investigated. The available interpretations of “open innovations” in the economic literature are summarized and the key markers of the analysed concept are identified. The classification of the principles of open innovation was further developed. A matrix of comparison of the properties of related methods of the openness paradigm in the innovation process was obtained. A dynamic system model of the open innovation development mechanism was developed.

Originality. The theoretical aspects of innovative development in the open innovation paradigm, which characterize the development of the principle of openness in a variety of related methods, have gained further development.

Practical value. The results of the conducted research can be applied to ensure further systematic research of the modern innovation process in the paradigm of open innovation and the formation of effective programs and tools to ensure their development in Ukraine.
Key words: open strategy, open innovation process, open innovation, innovative development, crowdsourcing, co-creation, socially responsible marketing.