bluuebunny/crossref_metadata_2025 huggingface dataset:
Structural Validity of the Rheumatology Attitudes Index in Systemic Sclerosis: Analysis from the UCLA Scleroderma Quality of Life Study
Authors: Gholizadeh Shadi , Mills Sarah D. , Fox Rina S. , Merz Erin L. , Roesch Scott C. , Clements Philip J. , Kafaja Suzanne , Furst Daniel E. , Khanna Dinesh , Malcarne Vanessa L.
Published: April 2017

Objective.

To evaluate the structural validity of the Rheumatology Attitudes Index (RAI), a widely used measure of rheumatic disease–related helplessness in patients with systemic sclerosis (SSc).

Methods.

Patients with physician-confirmed SSc from the University of California, Los Angeles (UCLA) Scleroderma Quality of Life Study (n = 208) received clinical examinations and completed self-report questionnaires. The structural validity of the RAI was examined through confirmatory and exploratory factor analysis (CFA/EFA).

Results.

A tenable factor structure was not identified through CFA or EFA.

Conclusion.

The present structural analysis did not support the use of the RAI with SSc patients.
Association Between Medications and Herpes Zoster in Japanese Patients with Rheumatoid Arthritis: A 5-year Prospective Cohort Study
Authors: Harada Sayoko , Sakai Ryoko , Hirano Fumio , Miyasaka Nobuyuki , Harigai Masayoshi
Published: April 2017

Objective.

To investigate the association between medications and herpes zoster (HZ) in patients with rheumatoid arthritis (RA) given biological disease-modifying antirheumatic drugs (bDMARD) or conventional synthetic DMARD in the clinical setting during 5 years using the Registry of Japanese Rheumatoid Arthritis Patients on Biologics for Longterm Safety (REAL) database.

Methods.

We calculated the crude incidence rate (IR) of HZ treated with systemic antiviral medications in 1987 patients from the REAL database. To estimate the association between HZ and medications, a nested case control study was performed with 1:5 case-control pairs matched for age, sex, observation start year, and comorbidity (HZ case group, n = 43; control group, n = 214). We calculated OR and 95% CI of the use of bDMARD, methotrexate (MTX), and corticosteroids for the occurrence of HZ using a conditional logistic regression analysis.

Results.

The median patient age was 60.0 years, female proportion was 81.5%, and median disease duration was 6.0 years. The crude IR (95% CI) of HZ was 6.66 (4.92–8.83)/1000 person-years. The OR (95% CI) of medication use were 2.28 (1.09–4.76) for tumor necrosis factor inhibitor (TNFi) and 1.13 (1.03–1.23) for oral corticosteroids dosage (per 1 mg prednisolone increment), both of which were significantly elevated. The OR of non-TNFi and MTX usage were not elevated.

Conclusion.

TNFi use and higher corticosteroids dosage were significantly associated with HZ in Japanese patients with RA in the clinical setting.
Validity and Reliability of Patient Reported Outcomes Measurement Information System Computerized Adaptive Tests in Systemic Lupus Erythematosus
Authors: Kasturi Shanthini , Szymonifka Jackie , Burket Jayme C. , Berman Jessica R. , Kirou Kyriakos A. , Levine Alana B. , Sammaritano Lisa R. , Mandl Lisa A.
Published: April 2017

Objective.

The aims of this study were to assess the construct validity and the test-retest reliability of Patient Reported Outcomes Measurement Information System (PROMIS) computerized adaptive tests (CAT) in patients with systemic lupus erythematosus (SLE).

Methods.

Adults with SLE completed the Medical Outcomes Study Short Form-36, LupusQoL-US version (“legacy instruments”), and 14 selected PROMIS CAT. Using Spearman correlations, PROMIS CAT were compared with similar domains measured with legacy instruments. CAT were also correlated with the Safety of Estrogens in Lupus Erythematosus National Assessment–Systemic Lupus Erythematosus Disease Activity Index (SELENA-SLEDAI) disease activity and the Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index (SDI) scores. Test-retest reliability was evaluated using ICC.

Results.

There were 204 outpatients with SLE enrolled in the study and 162 completed a retest. PROMIS CAT showed good performance characteristics and moderate to strong correlations with similar domains in the 2 legacy instruments (r = −0.49 to 0.86, p < 0.001). However, correlations between PROMIS CAT and the SELENA-SLEDAI disease activity and SDI were generally weak and statistically insignificant. PROMIS CAT test-retest ICC were good to excellent, ranging from 0.72 to 0.88.

Conclusion.

To our knowledge, these data are the first to show that PROMIS CAT are valid and reliable for many SLE-relevant domains. Importantly, PROMIS scores did not correlate well with physician-derived measures. This disconnect between objective signs and symptoms and the subjective patient disease experience underscores the crucial need to integrate patient-reported outcomes into clinical care to ensure optimal disease management.
Endocrine Comorbidities in Patients with Psoriatic Arthritis: A Population-based Case-controlled Study
Authors: Haddad Amir , Ashkenazi Ron Ilan , Bitterman Haim , Feldhamer Ilan , Greenberg-Dotan Sari , Lavi Idit , Batat Erez , Bergman Irina , Cohen Arnon Dov , Zisman Devy
Published: April 2017

Objective.

To investigate endocrine comorbidities in patients with psoriatic arthritis (PsA).

Methods.

A retrospective, cross-sectional study was performed with the database of Clalit Health Services, the largest healthcare provider in Israel, between 2002 and 2014. Patients with PsA were identified and matched by age and sex to healthy controls. The following morbidities were analyzed: hypo/hyperthyroidism, hypo/hyperparathyroidism, hyperprolactinemia, Cushing disease, Addison disease, diabetes insipidus, diabetes mellitus (DM), pituitary adenoma, acromegaly, and osteoporosis. Descriptive statistics were applied. The associations between PsA and endocrine comorbidities were analyzed by univariable and multivariable analysis.

Results.

The study included 3161 patients with PsA, 53.4% women, mean age 58.4 ± 15.4 years, and 31,610 controls. Comparative analyses yielded higher proportion of hypothyroidism (12.7% vs 8.6%, p < 0.0001), Cushing disease (0.3% vs 0.1%, p < 0.0001), osteoporosis (13.2% vs 9.1%, p < 0.0001), and DM (27.9% vs 20.7%, p < 0.0001) in the PsA group compared with the control group. In the multivariable regression analysis, the following diseases were more frequent in the PsA group: hypothyroidism (OR 1.61, 95% CI 1.47–1.81), DM (OR 1.35, 95% CI 1.18–1.42), Cushing disease (OR 3.96, 95% CI 1.67–9.43), and osteoporosis (OR 1.56, 95% CI 1.37–1.78).

Conclusion.

PsA is associated with a high frequency of hypothyroidism, osteoporosis, DM, and Cushing disease. Awareness of these comorbidities may help physicians provide the optimal medical care to patients with PsA.
Self-reported Diagnosis of Rheumatoid Arthritis or Ankylosing Spondylitis Has Low Accuracy: Data from the Nord-Trøndelag Health Study
Authors: Videm Vibeke , Thomas Ranjeny , Brown Matthew A. , Hoff Mari
Published: April 2017

Objective.

Self-reported diagnoses of inflammatory arthritis are not accurate. The primary study aim was to ascertain self-reported diagnoses of rheumatoid arthritis (RA) and ankylosing spondylitis (AS) in the Norwegian population-based Nord-Trøndelag Health Study (HUNT) using hospital case files. The secondary aim was to provide updated estimates of the prevalence and incidence of RA and AS.

Methods.

All inhabitants ≥ 20 years old from the county of Nord-Trøndelag were invited. Data from 70,805 unique participants from HUNT2 (1995–1997) and HUNT3 (2006–2008) were included. For participants who self-reported RA or AS, case files from all 3 hospitals in the catchment area were evaluated using standardized diagnostic criteria.

Results.

Of 2703 self-reported cases of RA, 19.1% were verified in hospital files. Of 1064 self-reported cases of AS, 15.8% were verified. Of 259 cases self-reporting both RA and AS, 8.1% had RA and 5.4% had AS. Overall, a self-report of 1 or both diagnoses could not be verified in 82.1%, including 22.8% with insufficient information or no case file. The prevalence of RA was 768 (95% CI 705–835) per 100,000. The incidence of RA from HUNT2 to HUNT3 was 0.48 (0.41–0.56) per 1000 per year. The prevalence of AS was 264 (228–305) per 100,000. The incidence of AS from HUNT2 to HUNT3 was 0.19 (0.15–0.24) per 1000 per year.

Conclusion.

Self-reported diagnoses of RA and AS are often false-positive. The prevalence and incidence of RA were comparable to reports from similar populations. The incidence of AS was higher than previously reported in a mixed population from Norway.
Case-control Study on Dactylitis, Enthesitis, and Anterior Uveitis in Spondyloarthritis Associated with Inflammatory Bowel Diseases: Role of Coexistent Psoriasis
Authors: Cantini Fabrizio , Niccoli Laura , Nannini Carlotta , Cassarà Emanuele , Kaloudi Olga , Rizzello Fernando , Gionchetti Paolo
Published: April 2017

Objective.

To evaluate the frequency of dactylitis, enthesitis, and anterior uveitis (AU) in spondyloarthritis (SpA) associated with inflammatory bowel disease (IBD-SpA) compared with other SpA, and to assess the role of associated psoriasis in the occurrence of dactylitis and enthesitis.

Methods.

In a 12-month case-control study, the frequency of dactylitis and enthesitis in 29 patients with ulcerative colitis (UC) and 59 with Crohn disease (CD) who satisfied the Spondyloarthritis international Society criteria for axial or peripheral SpA was compared with 176 controls, including 97 (55.1%) with psoriatic arthritis (PsA), 47 (26.7%) with ankylosing spondylitis (AS), and 32 (18.2%) with nonradiographic axial SpA (nr-axSpA). The occurrence of these features in IBD-SpA with and without psoriasis was also evaluated.

Results.

Axial, peripheral, or mixed involvement was observed in 46 (52%), 29 (33%), and 13 (15%) patients, respectively; and 14/88 (16%) had psoriasis. Dactylitis was recorded in 4/88 patients (4.5%) with IBD-SpA and in 30 controls (17.4%; p = 0.008), enthesitis in 16 cases (18.1%) and in 78/176 controls (44.3%; p < 0.001), and AU in 3 patients (3.4%) with IBD-SpA and in 26 controls (14.7%; p = 0.01). No significant differences were found between patients with UC-SpA and those with CD-SpA. Dactylitis and enthesitis were significantly more common in patients with IBD-SpA who also had psoriasis compared to those without skin disease (p = 0.009 and 0.003, respectively).

Conclusion.

Dactylitis, enthesitis, and AU are significantly less frequent in IBD-SpA compared with other types of SpA. Given the frequent association of psoriasis and IBD, overlooking coexistent skin disease may lead to overestimating the frequency of these features.
« Nous vieillirons ensemble »Destins des retrouvailles à l’orée de la retraite chez les femmes
Authors: Siaugues Caroline , Verdon Benoît
Published: April 2017

L’expérience du passage à la retraite paraît à même d’induire le trouble sur la scène psychique de bien des femmes. Souvent l’objet d’une chère attente associée au mérite et à la délivrance, la retraite professionnelle marque aussi l’avancée en âge et ne peut donc être pensée sans les problématiques qu’engage la traversée du vieillissement. À l’appui d’entretiens de recherche réalisés auprès de femmes retraitées, âgées entre 60 et 66 ans, cet article se propose d’appréhender tant la complexité que la singularité du travail psychique réclamé par cette expérience de passage en s’intéressant, plus particulièrement, aux retrouvailles avec le conjoint chez les femmes. Sous-tendues par la problématique de la dépendance et du vieillissement, ces retrouvailles peuvent mobiliser chez certaines la mise en place d’aménagements maniaques.
Matérialisme, eschatologie, nécessité
Authors: Untea Ionut
Published: April 2017

Pendant la première moitié du  xvii e siècle, les discours millénaristes enflamment l’imagination politique jusqu’au point d’inspirer l’exécution du roi Charles I er . À part sa portée politique, le projet millénariste anglais a aussi l’ambition de produire une vision scientifique de la manière dont la grâce divine agit sur les corps matériels. Arthur Dent, John Dury, Cheney Culpepper, Samuel Hartlib et Henry More font appel à l’image métaphorique de la pierre mise en mouvement par une puissance au-delà de toute force matérielle (Dn 2, 31-35). Afin de montrer que ce projet millénariste est insuffisamment fondé, même du point de vue théologique, Thomas Hobbes utilise la même image de la pierre, en lui donnant cette fois une interprétation dont le but est de souligner que les passions ne sont pas à mépriser. En intégrant la discussion sur les passions humaines dans sa vision scientifique sur le mouvement physique, Hobbes entend produire une théorie scientifique capable aussi d’être mise au service de l’unité religieuse et politique.
Current Understanding of the Health Effects of Electromagnetic Fields
Authors: Miah Tayaba , Kamat Deepak
Published: April 2017

There has been an exponential increase in the use of electronic devices over the past few decades. This has led to increased exposure to electromagnetic fields (EMF). Electric fields result from differences in voltage, whereas magnetic fields result from the flow of electric current. Higher-frequency waves of EMF have more energy than lower-frequency waves, and thus generally tend to be more harmful. An EMF activates cellular stress response and also causes breaks in DNA strands. There are many methodological barriers to effectively measuring the associations of EMF and childhood cancers. The consensus from multiple studies is that there is no causal role of extremely low-frequency EMFs in childhood cancers, including brain cancer. A recent study showed a link between EMF radiation and the development of malignant tumors in rats. In light of that study, the American Academy of Pediatrics set out new recommendations to decrease the adverse effects of cellphone exposure on children.

[
Pediatr Ann
. 2017;46(4):e172–e174.]
Overview of Sleep and Sleep Disorders in Infancy and Childhood
Authors: Carter John C. , Wrede Joanna E.
Published: April 2017

Sleep in children is an important and dynamic process, affecting numerous aspects of health and development. Problems with sleep are relatively common but often can be challenging to recognize. This article reviews the fundamental aspects of sleep in children from infancy to adolescence, and the most common and relevant sleep disorders likely to be encountered in a general pediatric practice. Where available, current evidence-based recommendations for management are discussed, including indications for referral to a sleep specialist.

[
Pediatr Ann
. 2017;46(4):e133–e138.]
Firearm Injury Prevention: The Role of the Clinician
Authors: Dowd M. Denise
Published: April 2017

More than 2,500 people younger than age 20 years die due to a firearm injury annually in the United States, and thousands more suffer injuries that are nonfatal. With nearly one firearm for every American in the US, exposure to a gun at some point during childhood or adolescence is highly likely. The high number of fatalities caused by firearms emphasizes the importance of primary prevention. This article calls on pediatricians to use their advantage as child development experts to discuss firearm injury prevention in clinical practice via a pragmatic and nonjudgmental approach.

[
Pediatr Ann
. 2017;46(4):e127–e130.]
La eliminación de metales tóxicos presentes en efluentes líquidos mediante resinas de cambio iónico. Parte IV: cromo(III)/H+/Lewatit SP112
Authors: Alguacil Francisco José
Published: April 2017

En este trabajo se presentan los resultados obtenidos en la eliminación de cromo(III) de disoluciones acuosas (pH 0-5) mediante la resina de intercambio catiónico Lewatit SP112. Se han investigado algunas variables que pueden afectar al sistema: influencia de la agitación, temperatura, pH y fuerza iónica del medio acuoso y cantidad de resina; también se ha investigado acerca de la selectividad del sistema cuando otros metales están presentes en el medio acuoso, comparándose los resultados de la eliminación del cromo(III) usando la resina con los resultados obtenidos cuando se emplea otro adsorbente como son los nanotubos de carbono de pared múltiple. Los resultados experimentales indican que la carga del cromo(III) en la resina responde mejor al modelo de Langmuir, mientras que los modelos cinéticos indican que la carga del metal en la resina responde al modelo de pseudo-segundo orden y difusión en la capa límite. La elución del cromo(III) se realiza con disoluciones de hidróxido sódico.
Les « énonciations de privilèges » dans le militantisme féministe en ligne : description et critique
Authors: Marignier Noémie
Published: April 2017

Cet article porte sur les « énonciations de privilèges » dans le militantisme féministe en ligne, c’est-à-dire sur les énoncés produits par des militant·es listant les privilèges de sexe-classe-race qu’illes possèdent ou qu’au contraire illes ne possèdent pas, dans un but de se situer par rapport aux diverses oppressions qu’illes subissent ou font subir. Après avoir décrit la forme et le fonctionnement pragmatique de ces énonciations ainsi que les courants féministes dans lesquels ils s’inscrivent, j’engage une critique de ces productions discursives de l’identité. Les énonciations de privilèges font en effet la part belle à l’illusion d’un sujet transparent et maître de son discours et échouent partiellement dans leur visée de produire des énonciations situées.
Les mots agonistiques des nouveaux discours féministes : l’exemple de grossophobie et cissexisme
Authors: Husson Anne-Charlotte
Published: April 2017

Cet article choisit une entrée lexicale pour appréhender les discours et argumentations féministes contemporaines. Plus précisément, ce sont deux mots agonistiques qui servent de points d’entrée : grossophobie / grossophobe et cissexisme / cissexiste. Ces mots agonistiques sont caractéristiques d’une recherche d’inclusivité qui trouve sa source dans un débat (entamé dès les années 1970) sur le sujet politique du féminisme. L’analyse d’un corpus d’énoncés tirés du web (sites, blogs, forum et réseaux sociaux numériques) révèle qu’au-delà de leur dimension polémique, de tels mots s’inscrivent dans une vision du monde où la prise en compte de la multiplicité des identités et des appartenances sociales tient une place cruciale.
Cultures politiques du discours : féminisme, anarchisme et rhétorique
Authors: Abbou Julie
Published: April 2017

Le féminisme a depuis longtemps identifié la langue comme un lieu primordial de la fabrique du genre, et donc comme un lieu de lutte. La langue est ainsi non seulement le théâtre d’interventions politiques féministes, mais également un objet de discussion récurrent. En s’intéressant à ce que des féministes disent de leur action sur la langue, on voit apparaître des métadiscours à motifs politiques. Dans cet article, je me pencherai sur certains des métadiscours du genre que l’on trouve dans la culture politique anarchiste. À partir de l’observation de ces pratiques, je propose de comprendre anarchisme et féminisme comme des cultures du discours, c’est-à-dire articulées autour d’une lecture du discours comme espace de pouvoir. Cet article défend l’idée qu’anarchisme, féminisme et rhétorique partagent une complicité épistémologique en ce que tous trois, dans certaines de leurs tendances, défendent une lecture du social et du discours comme hétérogène (vs. systémique) et sémiotique, ainsi qu’un questionnement de la production discursive du savoir au prisme des rapports de pouvoir.
Le corps exhibé : un texte singulier du féminisme quatrième génération
Authors: Pahud Stéphanie
Published: April 2017

Entre autres nouvelles élaborations argumentatives, la réflexion féministe contemporaine accueille un activisme non pas des mots, mais du corps : comme le relève Fraisse, si « le corps est évidemment partie prenante du fantasme et de l’image, au cœur des débats sur sexe et genre », il est aussi « une matière qui parle », « un langage de l’émancipation » (2014). La présente contribution prolongera cette observation en proposant une analyse discursive de corps féministes exhibés, ces derniers pouvant être considérés comme des textes de résistance. Elle sera plus précisément consacrée à une analyse discursive des pratiques corporelles du mouvement Femen, collectif féministe fondé en Ukraine en 2008, reconnaissable par sa nudité et ses « opérations coups de seins ». Il s’agira premièrement de décrire les particularités rhétoriques des corps-textes de ce mouvement : en adoptant des postures stéréotypiquement attribuées aux femmes et les stigmatisant, le collectif Femen investit politiquement le corps, et opère un détournement des exhibitions/aliénations (entre autres patriarcales) de ses performances. Enjeux et réception de ce retournement de stigmate seront discutés. Il s’agira également de réfléchir aux procédés discursifs de construction/déconstruction d’évidences sur le corps et aux modes possibles de repolitisation de ce dernier, envisagé ici comme instrument de communication/argumentation et comme lieu d’intelligibilité du social (Berthelot 1994).
Féminismes 2.0. Usages technodiscursifs de la génération connectée
Authors: Paveau Marie-Anne
Published: April 2017

Les univers discursifs numériques ouverts par le Web social ont permis le développement rapide des discours militants exploitant la réticularité des espaces numériques et leur capacité relationnelle. Après une description des usages numériques natifs actuels des féministes et de leur genèse historique, on examine deux phénomènes caractérisant le discours féministe contemporain : le déploiement dans la blogosphère et les RSN féministes de formes discursives natives et spécifiques de resignification de contenus agressifs ou insultants envers les femmes ; l’usage de technographismes, productions composites articulant image et texte de manière indissociable (on développe les deux exemples du mème « We can do it! » et du bingo féministe, liste d’arguments antiféministes présentés en ligne sur une grille analogue à celle du célèbre jeu).
La place et la parole des hommes féministes dans les réseaux sociaux numériques au Brésil
Authors: Zoppi Fontana Mónica Graciela , Oliveira Sheila Elias de
Published: April 2017

La présence d’hommes dans les manifestations féministes urbaines est fréquente. Cette présence est diffusée par les médias et surtout par la circulation des photos et de posts dans les réseaux sociaux. Des blogs dont les auteurs s’identifient comme hommes féministes/pro-féminisme se multiplient et produisent des effets polémiques sur les blogs féministes. La controverse est centrée sur la légitimité politique de la militance féministe par des hommes. Notre travail porte sur ce sujet une approche originale qui prend le langage comme objet d’analyse. Nous nous proposons d’examiner les effets de sens produits par la reprise des arguments féministes par des hommes et les opérations argumentatives mises en scène pour légitimer leur position énonciative. L’adjectivation et la prédication sont des indices qui nous aident à comprendre les enjeux de cette confrontation et à décrire les différentes positions occupées par les militants. Le corpus est composé d’énoncés (verbaux et verbo-iconiques) qui circulent dans la blogosphère militante et dans les communautés féministes et pro-féministes des réseaux.
Effective Statistical Methods for Big Data Analytics
Authors: Meng Cheng , Wang Ye , Zhang Xinlian , Mandal Abhyuday , Zhong Wenxuan , Ma Ping
Published: April 2017

With advances in technologies in the past decade, the amount of data generated and recorded has grown enormously in virtually all fields of industry and science. This extraordinary amount of data provides unprecedented opportunities for data-driven decision-making and knowledge discovery. However, the task of analyzing such large-scale dataset poses significant challenges and calls for innovative statistical methods specifically designed for faster speed and higher efficiency. In this chapter, we review currently available methods for big data, with a focus on the subsampling methods using statistical leveraging and divide and conquer methods.
Titus 3:3 as selfvilifikasie: �n Retoriese opsie
Authors: Genade Aldred A.
Published: April 2017

Titus 3:3 as self-vilification: A rhetorical option The rhetorical function of the vice list in Titus 3:3 remains to be accounted for. This article proposes that self-vilification, a novel rhetorical technique, be considered to investigate and propose a rhetorical function for Titus 3:3. The result is the identification and formulation of the overarching rhetorical objective of the verse in its totality. Titus 3:3 expresses a valuable corrective to Christian attitudes that could compromise the evangelistic or missiological mandate of the Church today.
Die opname van �n Jobgedig in enkele eietydse gedigte
Authors: Vos Cas J.A.
Published: April 2017

The reception of a Job poem in some contemporary poems This article investigates the intertextual influence of an ancient poem on a few modern-day poems. Other literary creations on which ancient poems have left their mark also come to the fore. The ancient poem under discussion here is a Job poem. This study reveals the remarkable creative influence that Job has exerted on literature. In Afrikaans poetry, a range of poets have concerned themselves with Job in their work. This article explores one such unpublished Afrikaans poem and an English translation thereof in order to point out how contemporary and relevant the Job poem really is.
A Beurling Theorem for Generalized Hardy Spaces on a Multiply Connected Domain
Authors: Chen Yanni , Hadwin Don , Liu Zhe , Nordgren Eric
Published: April 2017

The object of this paper is to prove a version of the Beurling–Helson–Lowdenslager invariant subspace theorem for operators on certain Banach spaces of functions on a multiply connected domain in ℂ. The norms for these spaces are either the usual Lebesgue and Hardy space norms or certain continuous gauge norms. In the Hardy space case the expected corollaries include the characterization of the cyclic vectors as the outer functions in this context, a demonstration that the set of analytic multiplication operators is maximal abelian and reflexive, and a determination of the closed operators that commute with all analytic multiplication operators.
CM Periods, CM Regulators, and Hypergeometric Functions, I
Authors: Asakura Masanori , Otsubo Noriyuki
Published: April 2017

We prove the Gross–Deligne conjecture on CM periods for motives associated with H2 of certain surfaces fibered over the projective line. Then we prove for the same motives a formula which expresses the K1-regulators in terms of hypergeometric functions 3F2, and obtain a new example of non-trivial regulators.
A Fatal Hantavirus Pulmonary Syndrome Misdiagnosed as Dengue: An Investigation into the First Reported Case in Rio de Janeiro State, Brazil
Authors: de Oliveira Renata Carvalho , Guterres Alexandro , Teixeira Bernardo Rodrigues , Fernandes Jorlan , Júnior João Marcos Penna , de Jesus Oliveira Júnior Reynaldo , Pereira Liana Strecht , Júnior João Bosco , Meneguete Patrícia Soares , Dias Cristina Maria Giordano , Bonvicino Cibele Rodrigues , D'Andrea Paulo Sérgio , de Lemos Elba Regina Sampaio
Published: April 2017

We report the results of an investigation into a fatal case of hantavirus pulmonary syndrome (HPS) in Rio de Janeiro State, Brazil, where the disease had not been reported previous to 2015. Following the notification of an HPS case, serum samples were collected from the household members and work contacts of the HPS patient and tested for antibody to hantaviruses. Seroprevalence of 22% (10/45) was indicated for hantavirus out of 45 human samples tested. Blood and tissue samples were collected from 72 rodents during fieldwork to evaluate the prevalence of hantavirus infection, by using enzyme-linked immunosorbent assay IgG, and to characterize the rodent hantavirus reservoir(s), by reverse transcription polymerase chain reaction and sequencing. Antibody prevalence was 6.9%. The circulation of a single genotype, the Juquitiba hantavirus, carried by two rodent species, black-footed pigmy rice rat (Oligoryzomys nigripes) and cursor grass mouse (Akodon cursor), was shown by analysis of the nucleotide sequences of the S segment. Juquitiba hantavirus circulates in rodents of various species, but mainly in the black-footed pigmy rice rat. HPS is a newly recognized clinical entity in Rio de Janeiro State and should be considered in patients with febrile illness and acute respiratory distress.
Automated Reporting of Trainee Metrics Using Electronic Clinical Systems
Authors: Levin Jonathan C. , Hron Jonathan
Published: April 2017

Background 

The Accreditation Council for Graduate Medical Education has called for increased emphasis on reporting objective performance measures to trainees and programs. However, reporting of objective measures, including clinical volume, is largely omitted from training programs.

Objective 

To use automated electronic medical systems at a tertiary pediatric care hospital to create a dashboard that reports objective trainee and program metrics, including clinical volume and diagnoses in a pediatrics residency.

Methods 

We queried an enterprise data warehouse that aggregates data daily from multiple hospital systems to identify patient encounters during which senior pediatrics residents at Boston Children's Hospital had entered documentation over a 9-month period. From this query, we created a filterable dashboard to display clinical volume and diagnosis data by individual resident and in aggregate.

Results 

A total of 44 of 45 senior residents (98%) in the program were included in analysis. We identified 12 198 patient encounters during which a senior pediatrics resident had entered documentation; these included a median of 332 inpatient encounters per resident, 122 emergency department encounters, and 84 outpatient encounters. The most common diagnoses stratified by clinical site were: inpatient – dehydration (median = 61); emergency department – long-term/current drug therapy (median = 16); and outpatient – encounter for immunization (median = 48).

Conclusions 

We used electronic health record systems to generate performance dashboards for trainees in a pediatrics residency across different sites of care with reported volume by diagnosis. Our dashboards provide feedback to program leadership regarding individual and aggregate trainee experience and allow individual trainees to compare their clinical exposure to peers.
Bias against Disconfirmatory Evidence in a large Nonclinical Sample: Associations with Schizotypy and Delusional Beliefs
Authors: Bronstein Michael V. , Cannon Tyrone D.
Published: April 2017

Bias against disconfirmatory evidence (BADE) is associated with delusion-like ideation and delusion-related aspects of schizotypy in nonclinical populations. Using a well-validated BADE assessment, we sought to demonstrate that only one of two facets of BADE (Evidence Integration Impairment, but not Positive Response Bias) accounts for these associations. To this end, 738 MTurk participants completed a survey which included the Schizotypal Personality Questionnaire (SPQ) and a version of the aforementioned BADE assessment. Using multiple regression, it was found that only Evidence Integration Impairment accounted for unique variance in delusion-related SPQ subscale scores. These results suggest, consistent with our hypothesis, that Evidence Integration Impairment might solely account for previously observed associations between BADE more generally and various cognitions/personality traits. It follows from this suggestion that in the general population ambiguous situations may combine with cognitive biases to maintain delusion-like ideation.
Are you Watching Me? Interacting Effects of Fear of Negative Evaluation and Social Context on Cognitive Performance
Authors: Maresh Erin L. , Teachman Bethany A. , Coan James A.
Published: April 2017

Socially anxious individuals exhibit cognitive performance impairments; it is unclear whether this is due to trait differences in abilities or effects of the experimental context. This study sought to determine how social context, individual differences in fear of negative evaluation (FNE), and task difficulty interact to influence working memory performance as indicated by effectiveness (accuracy) and efficiency (reaction times). Participants (N = 61) performed the n-back task at 2-back and 3-back difficulty levels under three conditions: alone (“Anonymous”), in presence of a non-evaluative experimenter (“Presence”), and under explicit performance evaluation by the experimenter (“Threat”). Overall, participants showed improved accuracy during Threat, but only on 2-back trials. FNE was positively associated with longer reaction times during Threat on 3-back trials. FNE did not relate to accuracy, suggesting that threat-related impairments tied to social anxiety may alter efficiency rather than effectiveness. Thus, social anxiety may elicit cognitive performance impairments even in minimally evaluative environments.
A Research Pathway for Experimental Psychopathology: The Role of External Validity Criteria
Authors: Davey Graham C L
Published: April 2017

This paper outlines a putative pathway for experimental psychopathology research developing psychological models of clinical disorders. The pathway uses established external validity criteria to define the pathway and clarifies the important role that research conducted on healthy participants can play in our understanding of clinical disorders. Defining a research pathway for experimental psychopathology in this way has a number of benefits It would (1) make explicit the need to address the external validity of developed models, (2) provide a clear set of criteria that would be required to extend research on healthy individuals to diagnostic populations, and (3) recommend using general psychological knowledge when developing models of psychopathology.
Repetitive Negative Thinking in Social Anxiety Disorder 2: Post-Event Processing
Authors: Sluis Rachel A. , Boschen Mark J. , Neumann David L. , Murphy Karen
Published: April 2017

Cognitive models of social anxiety disorder (SAD) emphasize post-event processing as a prominent maintaining factor that occurs after social-evaluative events. Post-event processing involves repetitive negative thinking revolved around perceived social failure. The present review concentrates on the relevant and available empirical literature on post-event processing in social anxiety which centres on Clarke and Wells (1995) theoretical framework. Correlational and experimental studies have investigated the relationship between post-event processing and the behavioural, physiological, cognitive and affective outcomes for socially anxious individuals. The majority of study designs include those investigating post-event processing in response to social-evaluative threat, and in response to treatment. Limitations of the existing literature are discussed and suggestions for future research examining the underlying cognitive functions of post-event processing are proposed.
Obsessive Patients and Deontological Guilt: A Review
Authors: Gangemi Amelia , Mancini Francesco
Published: April 2017

In line with the Appraisal Theories of Obsessive–Compulsive Disorder (OCD), in this review we present some experiments aimed at demonstrating the role of fear of guilt in OCD. What kind of guilt do OC patients want to prevent? Several studies suggest the existence of two different types of guilt emotions, namely deontological guilt and altruistic guilt. This research suggests that the former, more than the latter, is involved in OCD. Moreover, it demonstrates that the deontological guilt is related to disgust, and that this relationship could explain why both fear of contamination and fear of guilt are often co-present in obsessive patients. Finally, research shows that the Not Just Right Experience (NJRE) in OCD can be influenced by the deontological guilt. Future research should further verify the actual role of deontological guilt in OCD, and its therapeutical implications.
Linseed fibre - effect on composite flour properties and cereal products quality
Authors: Hrušková Marie , Švec Ivan
Published: April 2017

Wheat flour was fortified by 2.5 or 5.0 wt. per cent of linseed fibre, gained from seeds of golden flax varieties Amon and Raciol and brown one Recital (granulation 500 - 700 m), prepared from 2015 harvest. Technological quality of six flour composites was described analytically by Falling Number and Zeleny sedimentation test. Both screening methods shown a little impact on amylases activity and protein quality, respectively. Rheological tests included the farinograph, the extensigraph and the Rapid Visco Analyser (RVA) proofs. Additions of brown and yellow flax fibre significantly increased farinograph water absorption and shortened dough stability, somewhat stronger by addition of brown linseed fibre. Extensigraph curves course depended on dough resting time, higher differences between wheat control and flour composites were observed after 60 min dough resting. Linseed fibre supported dough extensibility, and energy as area under curve significantly decreased about 7 - 18%, mainly due to increasing alternative material portion in dough. In general, fibre is characterised as hydrophilic material, and pasting profiles of flour composites confirmed this experience. During dough leavening, tested samples were differentiated according to maturograph dough resistance; optimal leavening time of wheat-linseed fibre dough was shorter than control. Regardless described modifications in dough machinability, specific volumes of bread buns were similar though whole sample set. A weak worsening of buns vaulting reflected a partial dilution of dough gluten skeleton. Cut-off biscuits were characterised by gradually lowering spread ratio, correspondingly to elevated dough elasticity. Laboratory prepared elbow-pasta have the same cooking time as the control (8.0 min), and data variation could not be attributed to linseed fibre or addition level. All three cereal products were found to have acceptable sensory profiles. PCA method verified partial lowering of protein quality and pointed at tested sample differentiation according to linseed addition level.
An Investigation into Practices and Perceptions of Saudi University Learners of English towards Their Dictionaries’ Use for Learning Purposes
Authors: Samah A Almjlad Sultan
Published: April 2017

This study investigates the dictionary use practices of Saudi students. Twenty Saudi postgraduate students from both genders (12 males and 8 females) participated in the study. All participants were postgraduate students at the University of Salford in the UK. Questionnaire and interview were the instruments used to collect data. The study discovered a number of results regarding the research questions. The findings indicated that most of the Saudi learners used their dictionaries for finding the meaning of the target words followed by checking the pronunciation of the same word. The study discovered three serious problems that face Saudi EFL learners while using their dictionaries namely the difficulty in understanding the phonetic symbols, difficulty of finding the correct words and, in addition, insufficiency of illustrative examples given in the dictionary. Moreover, the study explored that the Arabic bilingual dictionary was the single most preferred dictionary in its paper format for their educational purposes. The study concluded with emphasising the prime importance of training in dictionary use, indicating that most of the Saudi learners did not receive any form of training on the use of dictionary.
SMEs Management Practices in a Hostile Business Environment in Zimbabwe
Authors: Moyo Bekezela , Moyo Edinah
Published: April 2017

A great deal of extant literature has emphasised the importance of SMEs role in the economic performance of any country. It is this realization that has propelled almost all countries to nurture their SMEs so as to achieve economic development. This paper intends to interrogate the management practices adopted by SMEs in Zimbabwe, particularly in Gweru metropolitan albeit the macro factors that bedevilled the country to date. To achieve this discussion, emphasis will be drawn to the adoption and adaptation of management practices by these SMEs particularly in four facets: management of human resources, cash management, management of capital assets, and management of the product/service.    This is a conceptual paper and a qualitative research design is going to be used to define the methodology of this paper. A cross sectional survey is proposed for this study, using a sample size of fifty SMEs who will be chosen using purposive and snowballing sampling methods. Questionnaires will be administered on the chosen sample and this will be followed by semi-structured interviews on five cases that will constitute the main cases for discussion and confirmation. Data will be analysed using a thematically data analysis approach as put forth by respondents narrating their encounters.
Hacia un pensamiento estratégico regional. Una perspectiva sudamericana
Authors: Riquelme Jorge , Faundes Cristián
Published: April 2017

Los autores presentan los avances en torno a la institucionalización de un sistema sudamericano en el ámbito de la defensa. Observan que, si bien es posible encontrar elementos que permitan configurar un pensamiento estratégico regional, estiman que como primer paso es preciso identificar los problemas comunes y tener la voluntad de solucionarlos en conjunto. En tal sentido, el artículo analiza los avances que se han dado en el marco del Consejo de Defensa Suramericano (CDS) en la configuración de un pensamiento estratégico propiamente regional, como un elemento clave para avanzar en la autonomía estratégica de América del Sur. Adicionalmente, se presentan algunos elementos que debería contemplar dicho pensamiento estratégico en el contexto del complejo escenario internacional actual.
A luta das comunidades indígenas Sawhoyamaxa e Apika’y: a Anistia Internacional e a questão das Terras Tradicionais
Authors: Vreche Carla Cristina , Silva Marcos Antônio da
Published: April 2017

O presente artigo objetiva analisar a prática do ativismo transnacional na luta pelo reconhecimento de terras indígenas. Nesse sentido, discute o reconhecimento dos direitos dessas comunidades sob a ótica do direito às suas terras ancestrais. Para tanto são apresentados os casos das comunidades Sawhoyamaxa e Apika’y, ambas objeto de campanha da ONG Anistia Internacional.
Self-care study in the Iranian medical students based on Islamic thought
Authors: Darabinia Morteza , Heidari Gorji Alimorad , Gholami Shirzad
Published: April 2017

Objective: This study aimed to investigate Islamic Self-care in Iranian medical students.Methods: In this descriptive study that was done in 2015, students of the Mazandaran University of Medical Sciences (faculties of health, paramedical, pharmacy, medicine and dentistry) were selected through classified random sampling. Study sample was calculated 269 from 900 students based on Krejcie and Morgan’s table. Data gathering was done using demographic and a standardized questionnaire about Islamic Self-care.Results: In this study, 269 students were entered to study. The mean (SD) score of Stipulation, Meditation, Calculation and Expostulation of students were 9.82 (2.35), 10.04 (2.85), 8.74 (2.65) and 7.64 (2.48) respectively. Results shows that correlation between all the components of the Self-care are positive and significant (p < .001).Conclusions: It is worthy that further study will be aimed to investigate ways to strengthen it, as well as explaining the benefits of Islamic Self-care among students with the theoretical and practical examples.
Figure of Speech in Bandung Historical Tourism Sites Naming
Authors: Sujatna Eva Tuckyta Sari , Pamungkas Kasno , Darsono Heriyanto
Published: April 2017

Many researchers do their research on figurative language or figure of speech, but it is limited research on figure of speech in historical tourism sites naming. The aim of this research is to investigate the figure of speech in historical tourism sites naming in Bandung area. The earlier study explained that the names of tourism destinations in Jawa Barat have different figure of speech and it happens to Bandung historical tourism sites naming. The method used by the present writers in this research is descriptive method. The descriptive method chosen by the present writers is used to identify and classify the names of the historical tourism sites in Bandung area as the data. From the various types of figure of speech referring to the theory, it is found that they are two types of figure of speech found in the data. The two figures of speech employed are personification (Gedung Merdeka and Gedung Indonesia Menggugat) and metaphor (Goa Belanda, Goa Jepang, Paris van Java, and Kota Kembang).
The Mediating Effect of Affective Organizational Commitment in the Relationship between Organizational Justice and Organizational Citizenship Behavior: A Conceptual Model
Authors: Alzayed Mohammad , Jauhar Junaimah , Mohaidin Zurina
Published: April 2017

A literature review revealed that the effect of organizational justice on organizational citizenship behavior (OCB) had been heavily examined as an overall relationship. However, there is a lack of research that examined the effect of organizational justice dimensions on OCB via affective organizational commitment as a mediator. Therefore, this research is an attempt to provide a value theoretical model that explains the relationships between dimensions of organizational justice and OCB as well as tries to describe in detail meaning of this relationship through the mediating effect of affective organizational commitment in the context of social exchange theory. Furthermore, the proposed hypotheses on the link between these variables are provided as a foundation for further research.
Toward the Blueprint of Campus-Based Ecosystems for Innovation
Authors: L. Romme A. Georges
Published: April 2017

The “science park” model has long been showing signs of aging, with many science parks now facing budget cuts by local and regional governments. In this study, we dissect the blueprint of a highly successful campus-based ecosystem, the High Tech Campus Eindhoven (HTCE). As an innovation ecosystem, the HTCE provides its residents (a) access to shared resources and facilities, to facilitate research and product development, and (b) an innovation community that enhances knowledge sharing between people at the campus. The success of the HTCE arises from a deep and inclusive understanding of the conditions in which an ecosystem for research and development can thrive, and the commitment to carefully grow and sustain these conditions. These conditions include: low physical distances between the various buildings, offices and shared facilities; a dynamic portfolio of thematic workshops and meetings stimulate knowledge sharing and informal networking; careful management of the diversity and reputation of the campus; attracting and hosting “connectors” that have the capability to initiate and/or manage collaboration across a newly emerging value chain; and a high level of responsiveness to requests and feedback of residents.