bluuebunny/crossref_metadata_2025 huggingface dataset:
Tratamento não cirúrgico de lesão periapical extensa com reparo da radiotransparência óssea periapical- Controle de um ano
Authors: Coelho Travassos Rosana Maria , Wiertz Cordeiro Renata , Barreto Silva Luciano , Guimarães Sampaio Trajano Dos Santos Pedro , Marques Nunes Adriana , Dos Santos Barroso Leonardo , Pasquini Luca , Lessa Cavalcanti de Araújo Vanessa , De Sá Rodrigues Verônica Maria , Farias do Prado Larissa Roberta , Augusta Maciel Tereza
Published: October 2024

Este estudo relatou o reparo de uma extensa lesão periapical extensa com diagnóstico sugestivo de periodontite periapical crônica. Paciente do sexo masculino de 46 anos de idade foi encaminhado ao endodontista para realizar tratamento endodôntico no incisivo lateral superior direito. Clinicamente, apresentou-se assintomático, resposta negativa ao teste de sensibilidade pulpar a frio realizado com gás refrigerante. Após anestesia, foi realizada a abertura coronária e o preparo cervical e médio do canal radicular com a lima Reciproc Blue R#40. O comprimento de trabalho foi determinado com localizador apical, seguido por irrigação com hipoclorito de sódio a 2,5%. O preparo apical foi realizado com sistema Reciproc Blue R#50, e a patência foraminal foi feita com a lima Glide 35.01 no forame apical. A obturação do sistema de canais foi realizada pela técnica do cone único, associado ao cimento Bio-C Sealer.  A proservação clínica e radiográfica foi realizada após seis meses e um ano da obturação do canal radicular, evidenciando-se reparo da radiotransparência óssea periapical. Conclui-se que o sucesso da terapia endodôntica é alcançado quando se realiza corretamente o diagnóstico, saneamento do sistema de canais e uma obturação hermética, bem como o selamento definitivo do acesso coronário.
Evaluación de la respuesta inmunitaria humoral en gallinas de doble propósito vacunadas contra la enfermedad de Newcastle en Vinto-Cochabamba
Authors: Quiroga Quiroz Gastón , Zambrana Copaja Ricardo
Published: October 2024

Introducción: La enfermedad de Newcastle es una enfermedad viral altamente contagiosa que afecta y causa grandes daños en aves domésticas y silvestres. Para su control, el mejor método es la vacunación, pero este procedimiento se realiza de diferente manera en aves de granja de crianza intensiva que en aves de traspatio en crianza familiar. Usar distintos protocolos y técnicas de vacunación pueden incrementar o disminuir la efectividad de la misma; en este trabajo se evalúa la eficiencia de un protocolo de vacunación actualmente utilizado para crear titulaciones proyectivas de anticuerpos contra Newcastle en la localidad de Vinto. Metodología: El presente estudio experimental evaluó la respuesta inmune humoral en una población de gallinas de doble propósito de traspatio proporcionadas por el Gobierno autónomo municipal de Vinto, vacunadas contra la enfermedad de Newcastle con el protocolo modificado de vacunación por vía oral, mezclando la vacuna con el alimento.  Se muestrearon aleatoriamente 66 individuos con dos repeticiones, teniendo 132 muestras serológicas de aves, las cuales fueron divididas en dos grupos: primo-vacunales y con vacunación previa. Adicionalmente, se tomaron muestras de suero previo a la vacunación y a las 4 semanas posteriores. Los títulos de anticuerpos se determinaron mediante el ensayo ELISA, y se compararon con test de ANOVA y análisis post-hoc de Tukey. Resultados: re realizo la primera evaluación de anticuerpos post-vacunales contra Newcastle en aves de traspatio en Bolivia. Los resultados no mostraron un aumento estadísticamente significativo de títulos de anticuerpos post-vacunales en los grupos respecto a títulos de anticuerpos en las aves pre-vacunación; Además, se presentó una alta variabilidad o des uniformidad de respuesta, mostrando deficiencias respecto a la eficiencia del protocolo de vacunación. Discusión: De forma contraria a estudios previos, la vacunación no indujo una adecuada respuesta de anticuerpos, y presentó una gran variabilidad al conferir protección humoral contra la enfermedad de Newcastle en gallinas ponedoras de traspatio, generándose un riesgo de bolsones de población no inmunizados. Se requieren intervenciones coordinadas entre productores, industria y gobierno para mejorar los programas de vacunación en la avicultura familiar y controlar de manera efectiva esta devastadora enfermedad aviar.
EFFICACY OF DEEP EUTECTIC SOLVENTS (DESs) FOR MITIGATING BIODETERIORATION IN CULTURAL HERITAGE: IN SITU EVALUATION
Authors:   Laboratory of Industrial and Synthetic Organic Chemistry (LISOC), Department of Chemistry and Chemical Technologies, University of Calabria, Via Pietro Bucci 12/C, 87036 Arcavacata di Rende (CS), Italy, STRANGIS Romina , MACCHIA Andrea ,   Department of Biology, Ecology and Earth Science (DiBEST), University of Calabria, Via Pietro Bucci, 87036 Arcavacata di Rende, CS, Italy; YOCOCU, YOuth in COnservation of Cultural Heritage, Via T. Tasso 108, Rome, 00185, Italy, GABRIELE Bartolo ,   Laboratory of Industrial and Synthetic Organic Chemistry (LISOC), Department of Chemistry and Chemical Technologies, University of Calabria, Via Pietro Bucci 12/C, 87036 Arcavacata di Rende (CS), Italy, MANCUSO Raffaella ,   Laboratory of Industrial and Synthetic Organic Chemistry (LISOC), Department of Chemistry and Chemical Technologies, University of Calabria, Via Pietro Bucci 12/C, 87036 Arcavacata di Rende (CS), Italy, LA RUSSA Mauro Francesco ,   Department of Biology, Ecology and Earth Science (DiBEST), University of Calabria, Via Pietro Bucci, 87036 Arcavacata di Rende, CS, Italy
Published: October 2024

The preservation of stone materials faces significant challenges due to biological deterioration, compromising the visual appearance and structural integrity of artifacts. Current cleaning treatments use toxic chemical biocides, with a high impact on the environment and human health. Research is turning to eco-friendly alternatives, such as Deep Eutectic Solvents (DESs), which offer a promising combination of biocidal properties and eco-friendly, as well as features such as biodegradability, non-flammability and non-volatility. This study defines the efficacy of Choline Chloride-based DESs reported in the literature as biocides in a real case study on an outdoor exposed magmatic effusive rock at the University of Calabria. Several analytical techniques were used to define DESs biocidal efficacy, monitoring their action for 6 months. This study contributes to the evidence of DESs' ability to keep treated surfaces clean, thus promoting the long-term preservation of materials. Macroscopic and microscopic observations, spectrocolorimetry, bioluminometry and FTIR spectroscopy have highlighted the significant potential of DESs as sustainable biocidal solvents for the preservation of stone materials exposed outdoors.
MULTI - ANALYTIC STUDY OF ORIENTAL MANUSCRIPTS IN BOSNIA AND HERZEGOVINA DATING FROM THE 15TH - 19TH CENTURY
Authors:   Department of Chemistry, Faculty of Science, University of Sarajevo, Zmaja od Bosne 33-35,
Sarajevo, Bosnia & Herzegovina, IBRAGIC Saida , ALIJAGIC Ajla ,   Department of Chemistry, Faculty of Science, University of Sarajevo, Zmaja od Bosne 33-35,
Sarajevo, Bosnia & Herzegovina; Academy of Fine Arts, University of Sarajevo, Obala Maka Dizdara 3, Sarajevo, Bosnia & Herzegovina, LJUBUSKIC Nejra ,   Department of Chemistry, Faculty of Science, University of Sarajevo, Zmaja od Bosne 33-35,
Sarajevo, Bosnia & Herzegovina; Academy of Fine Arts, University of Sarajevo, Obala Maka Dizdara 3, Sarajevo, Bosnia & Herzegovina, AVDIC Lamija ,   Department of Chemistry, Faculty of Science, University of Sarajevo, Zmaja od Bosne 33-35,
Sarajevo, Bosnia & Herzegovina; Academy of Fine Arts, University of Sarajevo, Obala Maka Dizdara 3, Sarajevo, Bosnia & Herzegovina, HUSEINAGIC Edib ,   Department of Chemistry, Faculty of Science, University of Sarajevo, Zmaja od Bosne 33-35,
Sarajevo, Bosnia & Herzegovina; Academy of Fine Arts, University of Sarajevo, Obala Maka Dizdara 3, Sarajevo, Bosnia & Herzegovina, HODZIC Ruhulah ,   Department of Chemistry, Faculty of Science, University of Sarajevo, Zmaja od Bosne 33-35,
Sarajevo, Bosnia & Herzegovina; Academy of Fine Arts, University of Sarajevo, Obala Maka Dizdara 3, Sarajevo, Bosnia & Herzegovina, RANOGAJEC Jonjua ,   University of Novi Sad, Faculty of Technology, Laboratory for Materials in Cultural Heritage, HeritageLab,
Bul. Cara Lazara 1, 21000 Novi Sad, Serbia, VUCETI Snezana ,   University of Novi Sad, Faculty of Technology, Laboratory for Materials in Cultural Heritage, HeritageLab,
Bul. Cara Lazara 1, 21000 Novi Sad, Serbia
Published: October 2024

The objective of this study was the analysis of materials used in five Oriental manuscripts from Bosnia and Herzegovina dating from the 15th - 19th century. The manuscripts were examined using various analytical techniques ranging from a series of preliminary tests (visual inspection, microchemical tests, thin layer chromatography (TLC), acidity status, UV fluorescence) to Fourier-transform infrared (FTIR) spectroscopy, X-ray fluorescence (XRF), optical and scanning electron microscopy (SEM-EDS). The obtained results showed that the manuscripts were made using paper, ink and pigments derived mainly from natural sources. The paper was made from either flax fibers or the combination of flax and hemp fibres and was often sized with egg white and alum to improve its quality. Both carbon black and iron-gall inks were used for the main text, whereas vermillion was chosen only for red ink. This research provides a valuable insight into the production techniques used in Oriental manuscripts from Bosnia and Herzegovina during that period. It also represents a template approach for manuscript characterisation and science-based paper conservation.
FROM RAG TO WOOD GOING THROUGH CEREAL: TECHNOLOGICAL REVOLUTION AMONG THE SCHOOL MAPS IN THE ARCHIVES OF THE UNIVERSITY OF GRANADA (SPAIN)
Authors:   University of Granada, Faculty of Arts, Edificio Restauración, Av. de Andalucía 27, 18014 Granada, Spain, REYES PÉREZ Ana , GÓMEZ HERNÁNDEZ Nuria ,   Group of Cellulose and Paper. Institute of Forest Science (ICIFOR-INIA), CSIC. Ctra. A Coruña, Km. 7,5. 28040 Madrid, Spain, ESPEJO ARIAS Teresa ,   University of Granada, Faculty of Arts, Edificio Restauración, Av. de Andalucía 27, 18014 Granada, Spain
Published: October 2024

School maps emerged as new type of document as a result of a series of technological and educational advances spanning the 18th to the 20th century. These maps originally played strictly functional and didactic roles. The passage of time has endowed them with an indisputable historical, documentary, scientific and even artistic character. Those currently housed in archives are generally poorly preserved due to issues related to their manufacture and general lack of concern for their safeguard after losing their original function. This study aims to characterise the materials serving to manufacture them by sampling a series housed in the Archives of the University of Granada, a task that is complicated by their multilayered nature (cloth, paper, printing inks and protective varnish). Preliminary identification of the fibrous elements reinforcing the papers and textiles by means of micro-invasive analytical techniques enables to subsequently define appropriate conservation and restoration protocols.
POPULATION STUDY AND REASSESSMENT OF CONSERVATION STATUS OF AN ENDEMIC DIPTEROCARP, Hopea bilitonensis
Authors:   Research Center for Biosystematics and Evolution – National Research and Innovation Agency (BRIN) – Jl. Raya Jakarta Bogor KM 46, Cibinong, West Java, INDONESIA 16911, ARIATI Siti Roosita , ROBIANSYAH Iyan ,   Research Center for Ecology and Ethnobiology – National Research and Innovation Agency (BRIN) – Jl. Raya Jakarta Bogor KM 46, Cibinong, West Java, INDONESIA 16911, WIDYATMOKO Didik ,   Research Center for Ecology and Ethnobiology – National Research and Innovation Agency (BRIN) – Jl. Raya Jakarta Bogor KM 46, Cibinong, West Java, INDONESIA 16911, RAKHMAWATI Sri Ulie ,   Independence Scholar – Pasir Mulya, Bogor, West Java, INDONESIA 16118, YUSWANDI Ade Yusup ,   Directorate of Scientific Collection Management – National Research and Innovation Agency (BRIN) – Jl. Raya Jakarta Bogor KM 46, Cibinong, West Java, INDONESIA 16911
Published: October 2024

Hopea bilitonensis is a rare, endemic Dipterocarp species in the Malesian Region. It has a disjunct distribution pattern, where main populations occur on the sandy soils of Bangka Belitung Islands of Indonesia and some on limestone forest in Perak, Peninsular Malaysia. Current global status of this species based on the IUCN Red List is Critically Endangered (CR) A1c+2c, B1+2c (1998) whilst in Malaysia it is assessed as CR A4c, B1ab(iii) (2010). A reassessment of the conservation status of this species is needed to provide the most current population status and its extinction risk, especially in Indonesia using the IUCN Red List Categories and Criteria version 3.1. This study was conducted to survey and assess the current populations of this species in Belitung Island where most population occurred and subsequently to recommend its current conservation status. The species is in fact still common in the island, stretching along the main roads and surrounding forests. Using the purposive sampling method, we developed a total of 16 plots of 20x20m each in 10 different locations across the Belitung Island. A total of 730 individuals were found with stem diameter at breast height ranged from 2cm to more than 30cm. For global reassessment, based on the current distribution and herbarium records, the calculated extent of occurrence (EOO) is 108,128.642km2, whilst the area of occupancy (AOO) is 84 km2. However, the species clearly has a restricted distribution and is facing high threats due to frequent timber harvesting and continuing decline of the EOO and AOO. The species extinction risk was then assessed by using five quantitative criteria of the IUCN. Therefore, we propose H. bilitonensis category is considered to be Endangered (EN) based on A2c, B2ab(i,ii,iii,iv,v) and C2a(i) criteria.
Communicating the dialog between painting and music with a mobile application
Authors: Vayanou Maria , Chrysanthi Angeliki , Pirpasou Eirini , Antoniou Angeliki , Katifori Akrivi
Published: October 2024

Contemporary visual artists often collaborate with musicians and composers to enrich their artworks and provide multisensory viewing experiences by leveraging the power of digital technology. In this paper, we present our approach to follow in their footsteps by creating a mobile application that provides “mixed-media interpretations” for a variety of visual artworks and music pieces, spanning over different time eras, with the objective to reflect the creative dialog and multifaceted interaction between their creators through time. Targeting the broader public, we attempt to capture a variety of interconnections between works of visual arts and music that may be of interest and are comprehensible to people with varying levels of knowledge on art or music, including not only inspirational but also personal and social relationships among the artists. We provide a six-layered conceptual model to ease the description of the content produced to that end while reporting several concrete examples. Then, we focus on how to communicate and digitally mediate the intertwined and often intricate interconnections in a concise way, proposing a “three-act” story scheme to progressively display short narratives on screen, combined with music reproduction on the mobile device. Finally, we explore the potential of the proposed approach through a user study with 15 participants and report a series of promising key findings, whereas also discussing future directions and pointing out open issues.
Оцінювання посухостійкості та зимостійкості інтродукованих сортів роду тюльпан (Tulipa L.)
Authors: Kunpan L. V. , Polishchuk V. V. , Osipov M. Yu.
Published: October 2024

Досліджено та проведено оцінювання зимо- та посухостійкості інтродукованих сортів тюльпанів групи раньоквітучих: класів прості ранні (Apricot Beauty, Flair, Sunny Prince), махрові ранні (Margarita, Monte Carlo, Pink Cameo); та середньоквітучих: класів Тріумф-тюльпани (Carola, Dynasty, Memphis, Alibi, Shirley dream, Holland Beauty), Дарвінові гібриди (Oxford Wonder, Golden Apeldoorn, Hakuun, World's Favorite, Salmon Impression). Дослідження проведено в Уманському національному університеті садівництва впродовж 2022-2024 рр. на дослідній ділянці кафедри садово-паркового господарства. Визначено, що досліджувані культивари мали високу стійкість до впливу низьких температур та здатність витримувати перегрів і зневоднення під впливом високих температур, не втрачаючи при цьому своїх екологічних особливостей. Виявлено, що у досліджуваних сортів Apricot Beauty, Flair, Sunny Prince, Shirley dream, Holland Beauty, Dynasty, Golden Apeldoorn, Oxford Wonder, World's Favorite, Salmon Impression зимостійкість була найкращою. Унаслідок здійснених досліджень тільки сорти Hakuun, Pink Cameo, Margarita виявилися менш стійкими до впливу низьких температур, але вони швидко відновлювалися і зберігали всі свої екологічні особливості. Дослідження посухостійкості тюльпанів показали їх високу стійкість до впливу високих температур навіть у найпосушливіші роки. Повністю зберегли свої екологічні особливості сорти Sunny Prince, Apricot Beauty, Margarita, Holland Beauty, Dynasty, World's Favorite, відповідно отримавши п'ять балів за шкалою оцінювання. Сорти Flair, Pink Cameo, Salmon Impression, Monte Carlo, Memphis, Shirley dream, Alibi, Carola, Golden Apeldoorn отримали чотири бали, тому що під впливом високих температур починали процес в'янення, однак при цьому, всі генотипи швидко відновлювалися й адаптовувалися за сприятливих умов. Визначено, що всі досліджувані генотипи є перспективними для подальшого їх використання в різних ландшафтних композиціях, оскільки вони адаптовані до складних умов урбогенного середовища.
Violence against women: a pedagogical proposal for promoting Critical Statistical Literacy
Authors: Sousa Igor Gabriel Santos de , Souza Leandro de Oliveira
Published: October 2024

The text is part of a research that aimed to study a pedagogical proposal developed and carried out with high school students from the theoretical perspective of Critical Statistical Literacy. Evidence was sought of the contributions that this theory could bring to the teaching and learning of statistics. The methodological technique used was participant observation, which developed from news published on social media about violence against women. Data collection was carried out using three instruments: video recording of the class; teacher's logbook; and videos created as a final task by students. The analysis indicates that the theoretical perspective adopted and the use of real data in statistics classes contribute to the development of criticality on social issues and statistical literacy. Thus, it became possible to offer conditions for implementing what is partially proposed in the curricular documents guiding Brazilian education.
Congenital Pulmonary Airway Malformation Type II and Challenge in the decision-making process in developing countries-a case report
Authors:   Komina Selim2 , Kostadinova Kunovska Slavica2 , Aneta Sima1 , Aliji Nurie3 , Veljanoski Darko4, Vesna Livrinova
Published: October 2024

Congenital Pulmonary Airway Malformation (CPAM) is a congenital lung disease that can be present from prenatal to childhood. The overall incidence of CPAM is reported to be 1 in 10,000 to 1 in 35,000 births, making it the most common type of congenital lung lesion. This malformation results from the interruption of lung development during various stages of embryogenesis. This case report aims to illustrate the disease through ultrasound imaging, emphasize its characteristics, and discuss parental counseling and decision-making regarding the continuation of pregnancy. It is important to highlight the limitations of prenatal diagnostic precision in developing countries and the need for additional diagnostic tools to improve parental decision-making options.
Health Insurance Provider Selection Through Novel Correlation Measure of Neutrosophic Sets Using TOPSIS
Authors: Mahapatra B.S. , Bera M.B. , Mondal M.K. , Smarandache Florentin , Mahapatra G.S.
Published: October 2024

Risk monitoring aims to recognize and control potential threats to our assets or health activities. Insurance is vital, as it compensates for any unexpected loss of property or life. Clients selecting the best health insurance provider must consider various factors and their relative significance to their circumstances. Multi-criteria decision-making (MCDM) helps people analyze and compare policy alternatives to find the best option. This research aims to assist potential health policy purchasers by addressing the selection of health insurance providers as an MCDM problem. The correlation coefficient is useful for identifying the importance of several conflicting criteria. The idea of correlation coefficients is extended in a neutrosophic context to capture the indeterminacy and incomplete information in the relationship among the criteria. The technique for order preference by similarity to an ideal solution (TOPSIS) approach is a useful and straightforward approach to solving MCDM problems. However, it often became ambiguous to researchers due to its involvement in the distance measure technique. The proposed neutrosophic correlation measure may also replace the ambiguity of using a suitable distance measure in the TOPSIS approach. This study extends the TOPSIS method by using the proposed neutrosophic correlation coefficient on single-valued neutrosophic sets (SVNSs). The criteria preferences are computed using a method based on the removal effects of the criteria (MEREC) approach. Some valuable concepts, like the weighted closeness measure of type I and type II and the weighted index parameter, are introduced with their properties to establish the proposed neutrosophic TOPSIS approach. An MCDM approach for health insurance providers has been constructed to illustrate the proposed approach numerically. The proposed method suggest that the health insurance provider ϒ2 is the most beneficial alternative, whereas ϒ1 is the least suitable. The client considers the terms and conditions for non-coverage and the facilities provided for pediatric and maternity care while buying health insurance. The comparative analysis of the suggested technique demonstrates the merit of the research in terms of consistency. The sensitivity analysis demonstrates the flexibility and robustness of the obtained results.
Teledentistry in the detection of oral potentially malignant disorders and oral cancer in the Latin American region: a review of literature with current possibilities
Authors: Pedroso Caique Mariano , Warnakulasuriya Saman , Santos-Silva Alan Roger
Published: October 2024

Teledentistry has emerged as a promising tool in bridging the gap in healthcare accessibility, particularly in regions like Latin America region, where resources for oral healthcare are often limited. Drawing upon a comprehensive review of literature, this overview assessed the applications and clinical outcomes of teledentistry in diagnosing oral potentially malignant disorders (OPMDs) and oral cancer, highlighting the challenges and opportunities specific to the Latin American context. Moreover, it examined the integration of artificial intelligence algorithms and teledentistry for enhancing diagnostic accuracy, thereby optimizing resource allocation and improving patient outcomes. By elucidating the current landscape and future prospects, this overview provided insights for policymakers, healthcare providers, and researchers, fostering advancements in oral healthcare delivery with the aim of reducing the burden of OPMDs and oral cancer in the Latin American region.
Bridging the evidence-practice gap for people with gout
Authors: Russell Mark D. , Galloway James B.
Published: October 2024

Gout is a common and disabling form of arthritis. Despite widely available, highly effective, urate-lowering therapies, such as allopurinol, studies continue to demonstrate poor care for individuals with gout in healthcare systems worldwide. In this commentary, we highlight strategies that can be utilised to overcome real-world barriers to optimal gout care, including allied health professional input, patient and clinician education, self-management strategies, and electronic health record solutions.
PENGARUH PROMOSI PENJUALAN, KEPUASAN DAN PENGALAMAN BERBELANJA ONLINE TERHADAP KEPUTUSAN PEMBELIAN PENGGUNA E-COMMERCE SHOPEE PADA MAHASISWA INSTITUT TEKNOLOGI DAN BISNIS NOBEL INDONESIA
Authors: Sari Winda Purnama , Mariah Mariah , Agunawan Agunawan
Published: October 2024

Winda Purnama Sari. 2024. Pengaruh Promosi Penjualan, Kepuasan dan Pengalaman Berbelanja Online terhadap Keputusan Pembelian Pengguna E-Commerce Shopee pada Mahasiswa Institut Teknologi dan Bisnis Nobel Indonesia, dibimbing Mariah dan Agunawan.
Penelitian ini bertujuan untuk menganalisis (1) Pengaruh secara parsial variabel promosi penjualan, kepuasan dan pengalaman berbelanja online terhadap keputusan pembelian pengguna e-commerce Shopee. (2) Pengaruh secara simultan variabel promosi penjualan, kepuasan dan pengalaman berbelanja online terhadap keputusan pembelian pengguna e-commerce Shopee. (3) Variabel yang paling dominan berpengaruh positif dan signifikan terhadap keputusan pembelian pengguna e-commerce Shopee
Sampel penelitian sebanyak 91 responden yang merupakan pengguna e-commerce Shopee pada mahasiswa Institut Teknologi dan Bisnis Nobel Indonesia, penelitian menggunakan metode analisis regresi linear berganda dengan pengumpulan data menggunakan kuesioner dengan skala likert.
Hasil penelitian menunjukkan bahwa (1) Secara parsial variabel promosi penjualan, kepuasan dan pengalaman berbelanja online berpengaruh positif dan signifikan terhadap keputusan pembelian pengguna e-commerce Shopee. (2) Secara simultan variabel promosi penjualan, kepuasan dan pengalaman berbelanja online berpengaruh positif dan signifikan terhadap keputusan pembelian pengguna e-commerce Shopee. (3) Variabel pengalaman berbelanja online yang paling dominan berpengaruh positif dan signifikan terhadap keputusan pembelian pengguna e-commerce Shopee.
Kata Kunci: Promosi penjualan, kepuasan, pengalaman berbelanja online dan Keputusan Pembelian.
Pengaruh Kedisiplinan Kerja, Lingkungan Kerja Fisik Dan Kepuasan Kerja Terhadap Kinerja Karyawan PT. XYZ
Authors: Sustikasari Alinda Pratama , Baskoro Heru
Published: October 2024

Penelitian ini dilaksanakan di PT. XYZ. Tujuan penelitian ini adalah untuk mengetahui Pengaruh Kedisiplinan Karyawan (X1), Lingkungan Kerja Fisik (X2) dan Kepuasan Kerja (X3), berpengaruh terhadap Kinerja Karyawan (Y) pada PT. Samudera Naga Global secara parsial. Populasi dalam penelitian ini yaitu seluruh karyawan yang ada di PT. XYZ yang berjumlah 51 karyawan. Metode teknik pengambilan sampel menggunakan metode teknik sensus jenuh dengan jumlah sampel 51 responden. Teknik analisis data dalam penelitian ini adalah regresi linear berganda dengan menggunakan SPSS 25. Hasil penelitian ini menunjukkan bahwa variabel Kedisiplinan Kerja (X1), Lingkungan Kerja Fisik (X2) dan Kepuasan Kerja (X3) berpengaruh terhadap Kinerja Karyawan secara parsial. Hasil koefisien Determinasi (R2) sebesar 0,937 menunjukkan bahwa besarnya pengaruh ketiga variabel bebas secara bersama – sama terhadap variabel terikatnya sebesar 93,7%.
Clinical application of oral contrast-enhanced ultrasound in evaluating the preoperative T staging of gastric cancer
Authors: Liang Yu , Jing Wan-Yi , Song Jun , Wei Qiu-Xin , Cai Zhi-Qing , Li Juan , Wu Ping , Wang Dong , Ma Yi
Published: October 2024

BACKGROUND

Oral contrast-enhanced ultrasound (OCEUS) is widely used in the noninvasive diagnosis and screening of gastric cancer (GC) in China.

AIM

To investigate the clinical application of OCEUS in evaluating the preoperative T staging of gastric cancer.

METHODS

OCEUS was performed before the operation, and standard ultrasound images were retained. The depth of infiltration of GC (T-stage) was evaluated according to the American Joint Committee on Cancer 8th edition of the tumor-node-metastasis staging criteria. Finally, with postoperative pathological staging as the gold standard reference, the sensitivity, specificity, negative predictive value, positive predictive value, and diagnostic value of OCEUS T staging were evaluated.

RESULTS

OCEUS achieved diagnostic accuracy rates of 76.6% (T1a), 69.6% (T1b), 62.7% (T2), 60.8% (T3), 88.0% (T4a), and 88.7% (T4b), with an average of 75.5%. Ultrasonic T staging sensitivity exceeded 62%, aside from T1b at 40.3%, while specificity was over 91%, except for T3 with 83.5%. The Youden index was above 60%, with T1b and T2 being exceptions. OCEUS T staging corresponded closely with pathology in T4b (kappa > 0.75) and moderately in T1a, T1b, T2, T3, and T4a (kappa 0.40-0.75), registering a concordance rate exceeding 84%.

CONCLUSION

OCEUS was effective, reliable, and accurate in diagnosing the preoperative T staging of GC. As a noninvasive diagnostic technique, OCEUS merits clinical popularization.
Harnessing the power of Calculus bovis: Anti-cancer properties and Wnt pathway modulation in hepatocellular carcinoma
Authors: Goyal Himanshi , Parwani Sachin , Fatima Kaneez , Kaur Jyotdeep
Published: October 2024

In this manuscript, we comment on the article, which explores the anti-cancer effects of Calculus bovis (CB) in tumor biology. We highlight its potential, particularly in hepatocellular carcinoma (HCC), where it inhibits the phosphatidylinositol 3-kinase/protein kinase B/mammalian target of rapamycin pathways and induces apoptosis. CB contains compounds such as oleanolic acid and ursolic acid that target interleukin-6, mitogen-activated protein kinase 8, vascular endothelial growth factor, and caspase-3, offering anti-inflammatory and hepatoprotective benefits. The manuscript also discusses CB sativus (CBS), an artificial substitute, which has shown efficacy in reducing hepatic inflammation and oxidative stress in animal models. We emphasize the need for further research on the effects of CBS on the gut-liver axis and gut microbiota, and on targeting Wnt signaling and M2 tumor-associated macrophage as potential therapeutic strategies against HCC.
Encapsulating taurine into liposomes: A promising therapeutic for liver fibrosis
Authors: Zhang Xue-Juan , Jiang Xiao-Yi , Ma Yi-Lin , Huang Fei-Yi , Huang Zheng-Wei
Published: October 2024

We summarize the mechanism by which taurine (Tau) inhibits autophagy and induces iron apoptosis in hepatic stellate cells. Tau interacts with autophagy regulates multifunctional proteins, microtubule-associated protein 1 light chain 3 Beta, and autophagy-related gene 5 to inhibit autophagy, binds to ferritin heavy chain 1 and nuclear receptor coactivator 4 to trigger ferritin autophagy, and interacts with glutathione peroxidase 4 to promote iron apoptosis. There is a solid rationale for developing Tau-based therapies targeting autophagy and ferroptosis regulation. From a pharmaceutical point of view, there are certain requirements for Tau protein delivery systems, such as loading efficiency, stability, and targeting. Nanomaterials should also contain a hydrophilic motif similar to Tau to optimize loading efficiency. Since Tau is a hydrophilic molecule with high water solubility, liposomes, micelles, and amphiphilic polymer nanoparticles may represent a superior choice. The nanostructure of the liposome includes a water region and a lipid membrane to sequester hydrophilic and hydrophobic drugs, respectively, whereas Tau is expected to be loaded into the water region. In addition, a representative method of actively targeting hematopoietic stem cells is introduced. A Tau-based method for the treatment of liver fibrosis is proposed based on the formulation of common liposomes (lecithin plus cholesterol).
УГОЛОВНО-ПРАВОВОЙ АНАЛИЗ ДЕЯНИЙ С ПРИЗНАКАМИ ЯТРОГЕНИИ
Authors: Самиулина Я.В.
Published: October 2024

Статья посвящена уголовно-правовому анализу деяний с признаками ятрогении (ятрогенных преступлений), изучены точки зрения ученых по их систематизации и содержательной характеристике, выявлены основные достоинства и недостатки имеющихся позиций по рассматриваемому вопросу в научном пространстве. Проведено исследование предложений по включению специализированных составов уголовно-правовой оценки «врачебных ошибок». Автор аргументирует свою точку зрения об отсутствии необходимости введения в Уголовный кодекс РФ специального состава об ответственности медицинских работников, предлагая в первую очередь легально сформулировать и разработать четкие грани понятия «врачебная ошибка», а также определить критерии «дефекта оказания медицинской помощи», разграничить правовое понятие «медицинская помощь» и «медицинская услуга», что позволит правоприменителю в каждом конкретном случае дать объективную уголовно-правовую оценку, поступал ли субъект (медицинский работник) добросовестно заблуждаясь или намеренно допустил наступление опасных для пациента последствий. В заключение проведенного исследования автор предлагает обобщенное определение деяний с признаком ятрогении. Выводы автора могут быть использованы в правоприменительной практике по решению вопросов квалификации деяний с признаками ятрогении, а также в дальнейших научных разработках по заявленной тематике.

The article is devoted to the criminal law analysis of acts with signs of iatrogeny (iatrogenic crimes), the points of view of scientists on their systematization and substantive characteristics are studied, the main advantages and disadvantages of the existing positions on the issue under consideration in the scientific space are revealed. A study of proposals for the inclusion of specialized elements of criminal law assessment of «medical errors» is carried out. The author argues his point of view that there is no need to introduce a special corpus delicti on the responsibility of medical workers into the Criminal Code of the Russian Federation, proposing, first of all, to legally formulate and develop clear boundaries of the concept of «medical error», as well as to determine the criteria for «defect in the provision of medical care», to distinguish between the legal concept of «medical care» and «medical service», which will allow the law enforcement officer in each specific case to give an objective a criminal legal assessment of whether the subject (medical worker) acted in good faith, mistaken or intentionally allowed the onset of dangerous consequences for the patient. In conclusion of the study, the author offers a generalized definition of acts with the sign of iatrogenia. The author's conclusions can be used in law enforcement practice to resolve the issues of qualification of acts with signs of iatrogeny, as well as further scientific developments on the stated topic.
ОБ ИСПОЛЬЗОВАНИИ ФОНОСКОПИЧЕСКОЙ ЭКСПЕРТИЗЫ В РАСКРЫТИИ И РАССЛЕДОВАНИИ ПЕНИТЕНЦИАРНЫХ ПРЕСТУПЛЕНИЙ, СОВЕРШАЕМЫХ С ИСПОЛЬЗОВАНИЕМ СРЕДСТВ МОБИЛЬНОЙ СВЯЗИ
Authors: Кубанов В.В. , Дериглазова О.А.
Published: October 2024

В статье исследуются проблемные вопросы назначения и производства фоноскопических экспертиз и использования их с целью раскрытия, расследования и предупреждения преступлений, совершаемых в условиях учреждений, обеспечивающих изоляцию от общества. Сделан вывод о том, что противоправное использование осужденными мобильных средств связи дает информационную основу для фоноскопических исследований, результаты которых, в свою очередь, составляют значительный объем доказательств по уголовным делам о пенитенциарных преступлениях. Приведены примеры использования фоноскопических экспертиз с целью установления квалифицирующих признаков преступления. Рассмотрена возможность получения необходимых для исследования образцов голоса посредством запроса фонограмм телефонных переговоров, записываемых интернет-сервисами для размещения объявлений о товарах и услугах. Анализируются проблемы проведения фоноскопических экспертиз в случае, когда речь на записи создана с помощью нейросетей, подражающих голосу реального человека. Отмечается, что на данный момент практически отсутствуют специальные методики, позволяющие установить, что речь была сгенерирована с помощью компьютерной программы. Предложено компенсировать отсутствие научно обоснованной методики выявления факта создания синтезированной речи проведением психолого-лингвистического исследования, которое по смысловому содержанию речи позволяет установить факт ее принадлежности конкретному субъекту.

The article examines the problematic issues of the appointment and production of phonoscopic examinations and their use for the purpose of disclosure, investigation and prevention of crimes committed in institutions providing isolation from society. It is concluded that the illegal use of mobile communication devices by convicts provides an information basis for phonoscopic studies, the results of which, in turn, constitute a significant amount of evidence in criminal cases of penitentiary crimes. Examples of the use of phonoscopic examinations in order to establish qualifying signs of a crime are given. The possibility of obtaining voice samples necessary for the study by requesting phonograms of telephone conversations recorded by Internet services for placing ads about goods and services is considered. The problems of conducting phonoscopic examinations are analyzed in the case when the speech on the recording is created using neural networks that imitate the voice of a real person. It is noted that at the moment there are practically no special techniques to establish that the speech was generated using a computer program. It is proposed to compensate for the lack of a scientifically based methodology for identifying the fact of creating synthesized speech by conducting a psychological and linguistic study, which, according to the semantic content of speech, allows us to establish the fact of its belonging to a specific subject.
INTEGRATING MEDIA EDUCATION INTO TRADITIONAL LEARNING WHEN TEACHING ENGLISH IN ELEMENTARY GRADES
Authors:   Namangan State University, department of Department of foreign languages Inter-Faculty teacher,1st year student of PhD, Uzbekistan, Akmalovna Valiyeva Shakhlo
Published: October 2024

This article cites several suggestions and techniques aimed at increasing the mediacompetency of Primary School students in teaching foreign languages hususan English and at the same time preventing them from following various misinformation.
SCIENTIFIC AND THEORETICAL ISSUES OF STUDYING THE HISTORY OF UZBEK KHAN ABDULLA KHAN II
Authors:   PhD, professor, head of “History” department of Kimyo International University in Tashkent, Uzbekistan, Zamonov Akbar
Published: October 2024

The article analyzes the personality of Shaybani Abdullah Khan, a great statesman who worked in the second half of the 16th century; the scientific-theoretical aspects of studying his history, historiography and source studies. Shaybanis, especially, the personality of Abdulla Khan, one of the largest representatives of the dynasty, his exclusion from research during the Soviet and independence periods, and ideological influences on his personality are discussed.
ANALYSIS OF THE APPLICATION OF FISCAL CORRECTIONS IN THE FRAMEWORK OF CALCULATING INCOME TAX PAYABLE
Authors: CAHYANI REGINA , BASRU WAWO Prof. Dr. H. ANDI , ASNI Dr. NUR
Published: October 2024

The income statement of PT Anugrah Abadi, which adheres to the Financial Accounting Standards (SAK), is included in the financial statements based on research. Both internal and external parties use this report to calculate taxable income and make decisions. The primary objective of fiscal correction is to determine the extent of underpayment or overpayment of corporate income tax for PT Anugrah Abadi by performing fiscal corrections on the financial statements and reanalyzing the fiscal corrections and expenses recorded by PT Anugrah Abadi in accordance with tax laws. The method used in this research is a descriptive qualitative approach with data processing. The data sources used in this research are the financial statements and tax reports of PT Haleyora Power for the year 2023. The results indicate that there are several financial statement accounts subject to fiscal corrections. Within the fiscal corrections, some expense accounts were adjusted positively and negatively, including sales expenses and general administrative expenses. Consequently, the fiscal correction of PT Anugrah Abadi’s commercial financial statements has increased.
Processing of Milkfish and Moringa Flour as Alternative Superfoods for Handling Stunting in Bone Regency
Authors: Musni Musni , Malka St. , Syam Azniah
Published: October 2024

Stunting has a big influence on children's growth and development, both motoric and verbal development. Stunting can be prevented by fulfilling quality energy intake. Modification of additional food for toddlers by using local food through a touch of technology is the strategy offered in this research. This study aims to evaluate the effect of fortification of Moringa leaf flour in milkfish crackers on organoleptic characteristics, including color, aroma, texture and taste. The cracker samples were fortified with Moringa leaf flour at concentrations of 0%, 2.5%, 5% and 7.5%. The assessment is carried out by panelists who provide scores for each parameter. The results showed that fortification up to 2.5% did not affect color and aroma, and improved texture, but reduced taste acceptability. Fortification at levels of 5% and 7.5% reduced the acceptability of taste and color although the texture remained good.
Profesyonel Sürücülerde Psikolojik Semptomların ve Uyku Kalitesinin Sürücü Davranışlarına Etkisi
Authors: Çorak Tuncay , Akay Ayça
Published: October 2024

Alanyazında, profesyonel sürücülerdeki yüksek kaza oranları ve buna bağlı kayıplar, önemli kamusal problemlerden biri olarak kabul edilmektedir. Profesyonel sürücülerin kaza oranlarının artmasında, sapkın sürücü davranışlarının belirleyici olduğu ve bu davranışların birçok farklı değişkenin yanı sıra psikolojik semptomlar ile uyku kalitesi göstergelerinden etkilendiği bildirilmektedir. Ayrıca, profesyonel sürücülerle yürütülen mevcut çalışmaların, psikolojik semptomlar ve uyku kalitesinin sapkın sürücü davranışlarına olan etkilerini birlikte değerlendirmediği görülmektedir. Bu çalışma ile profesyonel sürücülerde demografik değişkenlerin yanı sıra psikolojik semptomların ve uyku kalitesine dair göstergelerin, sapkın sürücü davranışları üzerindeki yordama gücünün birlikte değerlendirilmesi amaçlanmaktadır. Çalışmanın örneklemini 176 profesyonel sürücü oluşturmaktadır. Veriler, Demografik Bilgi Formu, Depresyon Anksiyete Stres Ölçeği, Pittsburgh Uyku Kalitesi İndeksi, Epworth-Uykululuk Ölçeği ve Sürücü Davranışları Ölçeği aracılığıyla toplanmıştır. Çalışma kapsamında değişkenler arasındaki ilişkiler Pearson korelasyon analizi; demografik değişkenlerin, psikolojik semptomların ve uyku kalitesine dair göstergelerin yordama gücü ise hiyerarşik regresyon analizi ile değerlendirilmiştir. Hiyerarşik regresyon analizi bulguları, anksiyetenin hataları ve ihmalleri, stresin saldırgan ihlalleri, uykululuğun ise sıradan ve saldırgan ihlalleri yordadığını göstermektedir. Bu bulgular, profesyonel sürücülerde trafik güvenliğini etkileyen sapkın sürücü davranışlarının azaltılmasına yönelik müdahaleler geliştirilirken, psikolojik semptomların ve özellikle uykululuğun değerlendirilmesi gerektiğinin önemini göstermektedir. Bununla birlikte, çalışmanın bulguları ilgili alanyazın kapsamında tartışılmış ve trafik güvenliğinin artırılmasına yönelik öneriler sunulmuştur.
Factors Affecting the Academic Performance of the CCJE Students for School Year 2018-2021
Authors: D. Cabangan Shierly , A. Bartolome Amyneth
Published: October 2024

The study generally aimed to determine the factors affecting the Academic Performance of the CCJE students for the school year 2018-2021. Specifically, the following variables are examined: the profile of the respondents, factors affecting the academic performance of the students in terms of the General Weighted Average (GWA), Psychological and Emotional Factors, and Learning Facilities. The researchers made use of the descriptive-correlational method of research The primary data-gathering tools used in the study were a self- structured questionnaire and a documentary analysis made from the records of the Office of the Registrar for the General Weighted Average. The study respondents comprised 97 male and 59 female fourth-year BS Criminology and BS LEA students of ISU Cabagan Campus during the school year 2018-2021. Findings revealed that the majority of the respondents were Males and the students performed well in their academics in the years 2020-2021 to 2021-2022. Further, the respondents rated Psychological and Emotional factors and Learning Facilities as moderately affecting their academic outcomes. It also revealed no significant relationship between the GWA, Psychological/Emotional stress, and Learning Facilities concerning the student’s academic performance. Similarly, there is no significant difference between GWA, psychological/emotional factors, and learning facilities when grouped according to sex.
Revisiting Keith Hitchins’s Oxford History of the Romanians and Romania, 1774–1947
Authors: Michelson Paul E.
Published: October 2024

The purpose of the article is to revisit, after a quarter of a century, Professor Keith Hitchins’s two-volume Oxford synthesis of Romanian history from 1774 to 1947. It will summarize his principal premises and conclusions and then assess how well his findings have held up since then.
Positive Influence: Negotiating a Church Historiographical Canon with the West
Authors: Șincan Anca
Published: October 2024

The present article discusses the way in which the historiographical canon on the history of the Orthodox and Greek Catholic Churches in Transylvania during the eighteenth and nineteenth centuries was reconceptualized during and in the aftermath of the academic visit of Western specialists in Romania. Keith Hitchins’s visit to Romania in the early 1970s to undertake research in the church archives for his work on the history of the Romanian intelligentsia in the Austro-Hungarian Empire made an impact on how the history of the Greek Catholic Church was portrayed in the religious journals of the Romanian Orthodox Church. The subtle shifts in the canon included distinguishing the Greek Catholics from the Orthodox in Transylvania and reintroducing the Greek Catholic interwar historiography into the interpretation.
A novel hybrid model for predicting the bearing capacity of piles
Authors: Tao Li , Xue Xinhua
Published: October 2024

Due to the uncertainty of soil condition and pile design characteristics, it is always a challenge for geotechnical engineers to accurately determine the bearing capacity of piles. The main objective of this study is to propose a hybrid model coupling least squares support vector machine (LSSVM) with an improved particle swarm optimization (IPSO) algorithm for the prediction of bearing capacity of piles. The improved PSO algorithm was used to optimize the LSSVM hyperparameters. The performance of the IPSO-LSSVM model was compared with seven artificial intelligence models, namely adaptive neuro-fuzzy inference system (ANFIS), M5 model tree (M5MT), multivariate adaptive regression splines (MARS), gene expression programming (GEP), random forest (RF), regression tree (RT) and a stacked ensemble model. Six statistical indices (e.g., coefficient of determination (R2), mean absolute error (MAE), root mean squared error (RMSE), relative root mean squared error (RRMSE), BIAS and discrepancy ratio (DR)) were used to evaluate the performance of the models. The R2, MAE, RMSE, RRMSE and BIAS values of the IPSO-LSSVM model were 1, 4.27 kN, 6.164 kN, 0.005 and 0, respectively, for the training datasets and 0.9977, 22 kN, 36.03 kN, 0.0275 and –11, respectively, for the testing datasets. Compared with the ANFIS, MARS, GEP, M5MT, RF, RT and the stacked ensemble models, the proposed IPSO-LSSVM model shows high accuracy and robustness on the test datasets. In addition, the sensitivity, uncertainty, reliability and resilience of the IPSO-LSSVM model were also analyzed in this study.
First published online 22 October 2024