bluuebunny/crossref_metadata_2025 huggingface dataset:
Gender specific syntagmatic peculiarities of phrasal rhythm in the course of extemporaneous reading aloud (American English)
Authors: Bankov A. S.
Published: June 2022

The article considers the methods, the major stages and results of the study of how gender influences the syntagmatic properties of phrasal rhythm in the course of extemporaneous reading aloud in contemporary American English. The given description is the second stage of the study focusing on the influence of gender on phrasal rhythm in the type of language activity being considered. Previously, gender specific male and female “repertoires” of statistically valid types of rhythmical groups (i.e. the paradigmatic properties of rhythmical groups) were determined. A rhythmical group is understood as a suprasyllabic prosodic unit comprising one stressed and a number of unstressed syllables adjacent to it. The position and the number of the unstressed syllables in the rhythmical group determine its type. At this stage of the study, the peculiarities of the combinability of different types of rhythmical groups and their valency are being scrutinized. In the realm of combinability peculiarities of rhythmical groups, the statistics of the types and kinds of observed contacts are being analyzed: contrastive/non-contrastive increase/decrease of rhythm, the rate of rhythm changes as well as cases of unchanged rhythm. Statistically valid genderfactored differences are being determined. Among the statistical tools the following were mostly employed: measures of central tendency (the mean value), measures of variability (dispersion) and the probability theory (to determine the valency). It has been established that the type of the language activity, which is being considered here, allowing almost no freedom of the speakers to organize the phrasal rhythm at their own discretion, greatly influences the results. Thus, male and female manifestations in a vast number of indicators show no statistically relevant differences, especially when group mean values are considered. The majority of statistically valid gender specific differences are observed only in the values of dispersion, which show the degree of uniformity, immutability of the events. The discussion section of the article represents the author’s speculation about the accuracy and efficiency of the auditory-functional method that is being employed to determine the contrastive/non-contrastive rhythm modulation: by the difference in the number of unstressed syllables between the adjacent rhythmical groups without regard given to their positions relevant to the stressed syllable. Eventually the author concludes that the controversy of the method is to be smoothed out by the acoustic analysis of the actual data.
A indignidade sucessória do artigo 2034.o, alínea a), do Código Civil português – Pode ser dispensada a específica declaração judicial de indignidade sucessória do criminoso em relação a cada uma das heranças posteriormente abertas por óbito das pessoas aí mencionadas?
Authors: Remédio Marques João Paulo
Published: June 2022

A conduta indigna dos herdeiros ou legatários em relação ao autor da sucessão pode assumir várias modalidades relevantes para o direito sucessório português. Uma delas é o homicídio doloso, ainda que não consumado, contra o autor da sucessão. O acórdão do Supremo Tribunal de Justiça (STJ), de 23.02.2021 gera, na nossa opinião, uma interpretação normativa materialmente inconstitucional da norma do art. 2034.o, alínea a), do Código Civil, ao ter decidido que “a declaração de indignidade [por homicídio doloso] em relação à sucessão do autor da sucessão estende-se à sucessão do seu cônjuge e familiares mais próximos, não sendo necessárias várias declarações de indignidade”. O presente estudo pretende demonstrar que essa declaração de indignidade sucessória efetuada no quadro da ação penal dirigida contra o indigno (no caso, o homicida doloso) tem eficácia relativa e não pode comunicar-se automaticamente às pessoas mencionadas nas alíneas a) e b) do art. 2034.o do Código Civil, sendo necessárias específicas e concretas declarações de indignidade relativamente às heranças dessas pessoas se e quando o indigno lhes sobreviver.
Malignant peripheral nerve sheath tumor with rhabdoid features arising in the temporal region of a patient suffering from neurofibromatosis 1 – A case report
Authors:   Oral & Maxillofacial Pathology Department, Faculty of Dentistry, Cairo University, Egypt, Amer Hatem , Shaheen Hamed ,   Craniomaxillofacial Program, Naser Health Institute, Cairo Egypt, Ashoub Madiha ,   Oral Pathology Department, Faculty of Oral and Dental Medicine, Misr International University, Cairo, Egypt, Mahmoud Sarah ,   Oral & Maxillofacial Pathology Department, Faculty of Dentistry, Cairo University, Egypt
Published: June 2022

The malignant peripheral nerve sheath tumor is one of the rare sarcomas that have a challenging diagnosis. It occurs independently with neurofibromatosis type 1. Some studies referred that malignant peripheral nerve sheath tumor attains a worse prognosis when it occurs in the head and neck region. In the reported case, a male patient with neurofibromatosis type 1 manifestations presented with a large mass in the temporal region. Based on the clinical history, histopathology, and immunohistochemical findings, the lesion was diagnosed as a low-grade malignant peripheral nerve sheath tumor with rhabdoid features. Surgical resection followed by intensity-modulated radiotherapy was the treatment of choice.
Synthesis, molecular docking and antimicrobial evaluation of octadecanoic acid [4-(5-phenyl-4,5-dihydro-1H-pyrazol-3-yl)phenyl]-amide pyrazoline derivatives
Authors: Tsurho Shurhovolie , Maddela Prabhakar
Published: June 2022

A new series of octadecanoic acid [4-(5-phenyl-4,5-dihydro-1H-pyrazol-3-yl)phenyl]-amide pyrazoline derivatives were designed synthesized, and characterized by spectral analysis (IR, MS, 1H-NMR, 13C-NMR). The compounds were screened for in vitro antibacterial activity against Escherichia coli and Staphylococcus aureus. All the compounds exhibited significant antibacterial activity with minimum inhibitory concentrations ranging from 1.2 to 2.5 mg/mL. The newly synthesized compounds were also found to have good anti-fungal activity against Fusarium oxysporum and Penicillium italicum, with all the compounds showing MIC of 2.5 mg/mL for both the fungal strains. Molecular docking studies were also incorporated to elucidate the possible interactions of the synthesized compounds with bacterial and fungal proteins.
Anticonvulsant Activity of Helianthus tuberosus Against Maximal Electroshock Induced Convulsions in Rats
Authors: KADAM NAGNATH RAMRAO , Mohanty Pradeep Kumar , Jain Ashish
Published: June 2022

Epilepsy is an episodic brain dysfunction featured by recurring erratic spontaneous seizures followed by cognitive, social, neurobiological, and psychological consequences. Conventional anti-epileptic drugs are associated with several untoward effects, and hence long-term treatment compliance is a major problem in the management of epilepsy. Herbal drugs have shown promising efficacy as potent anticonvulsants in the past few years. In light of this, the anticonvulsant effect of alcoholic extract of leaves of Helianthus tuberosus (AHT) against maximal electroshock (MES) induced convulsions was investigated. In the present investigation, an indigenous plant, H. tuberosus was studied for its protective effect against maximal electroshock (MES) induced convulsions in Wistar albino rats. The rats were pre-treated with different doses (100, 200, 400 mg/kg) of alcoholic extract of leaves of H. tuberosus for 14 days, and then, they were subjected to maximal electroshock seizures (40 mA for 0.2 seconds) treatment. Alcoholic extract of leaves of H. tuberosus at the dose of 400 mg/kg significantly reduced the duration of hind limb extension and the protection of rats against maximal electroshock-induced seizures. The reference standards phenytoin (20 mg/kg) provided complete protection. Thus, the present study revealed an anticonvulsant effect of H. tuberosus against maximal electroshock-induced convulsions in rats.
Stability Indicating Method Development and Validation for the Estimation of Bempedoic Acid and Ezetimibe by Reverse Phase– Ultra Performance Liquid Chromatography
Authors: Molleti Divya , Amgoth Krishnamanjari Pawar , Pallekona Sushma
Published: June 2022

A simple, accurate, precise method was developed to simultaneously estimate the bempedoic acid (BEM) and ezetimibe (EZT) in bulk and pharmaceutical dosage form using RP-UPLC. Combination of bempedoic acid and ezetimibe is used to treat adults with heterozygous familial hypercholesterolemia or established atherosclerotic cardiovascular disease. Chromatographic separation was carried out using X-Bridge phenyl 150 x 4.6 mm, 3.5 μ column at a 1.0 mL/min flow rate. The mobile phase consisted of 0.1% formic acid buffer and acetonitrile (70:30%v/v). The retention times of BEM and EZT were found to be 1.157 and 3.208 minutes, respectively. The temperature was maintained at ambient. The optimized wavelength for BEM and EZT was 230 nm. The method developed has been statistically validated according to ICH guidelines. %RSD of BEM and EZT were and found to be 0.6 and 1.4, respectively. %Recovery was obtained as 100.0% and 101.40% for BEM and EZT, respectively. LoD, LoQ values were obtained from regression equations of Bempedoic acid and Eetimibe were 0.27 μg/mL, 0.015 μg/mL and 2.7 μg/mL, 0.15 μg/mL respectively. The method obeys Beer’s law in the concentration range of 27–337.5 μg/mL (R2 = 0.9991) for BEM, and 1.5–18.75 μg/mL (R2 = 0.9993) for EZT. The method showed good reproducibility and recovery with %RSD less than 2. Forced degradation studies established the stability-indicating capability of the method under stress conditions like acid, base, peroxide, UV, thermal, humidity. Retention times were decreased and that run time was decreased. Hence, the chromatographic method developed was simple and economical and can be adopted in regular quality control test in Industries. It is said to be rapid, specific, sensitive, robust, and reliable and can be effectively applied for routine analysis in research institutions, quality control departments in industries.
A Comprehensive Review on Brugada Syndrome: Etiology, Hormonal role, Current Treatment Regimen, and Role of Polyunsaturated Fatty Acids
Authors: Bhattacharjee Bedanta , Das Parikshit , Ikbal Abu Md Ashif , Baidya Ritika , Choudhury Ankita
Published: June 2022

Brugada syndrome is a disorder caused by alteration or mutation in the ion channels, abnormal ECG resulting in elevated ST segment and blockage of right bundle brank. It has a genetic history and can be passed down from the parents to their offspring and may be further complicated if someone already had a cardiac arrest or other cardiac-related issues. At present, there is no permanent cure strategy available to treat this disorder. However, some surgical and pharmacological intervention approaches, such as the use of defibrillators, catheters can provide some relief, but due to their excessive cost and complications, their use has been limited. Polyunsaturated fatty acids (PUFA) components: Eicosapentaenoic acid and docosahexaenoic acid were found to play a significant role in reducing the cardiovascular events and mortality rate. The primary sources of these fatty acids are fish and fish oils. This review attempts to summarize the cardioprotective role of PUFA in preventing ventricular arrhythmias and Brugada syndrome through alteration of cardiac ion channels.
Formulation development and evaluation of site specific periodontal fibers of metronidazole and minocycline hcl
Authors: Kumar Kokkilagadda V. , Sasidhar Reddyvalam L. C. , Deepthi Bandarupalli
Published: June 2022

Periodontal disease is a collective term for a variety of pathological conditions characterized by relapse and inflammation of the gums, periodontal sinews, alveolar bone, and dental cementum. It is a confined inflammatory reaction caused by bacterial infection of a periodontal pocket in conjunction with subgingival plaque. Even though bacteria are the primary cause of periodontal disease, the presence of microbial pathogenic aspects may not be required to cause periodontitis. Periodontal pathogens produce harmful byproducts and enzymes that disrupt extracellular matrices as well as host cell membranes in order to produce nutrients for their growth. A number of antimicrobial products are summarized, as well as the composition of the delivery systems, their use, clinical results, and release. The goal of using an intrapocket device for antimicrobial agent delivery is to achieve and maintain therapeutic drug concentration for the desired period of time. With precise control of the rate at which a specific drug dosage is released from a delivery system without the need for frequent administration, novel controlled drug delivery systems are capable of improving patient compliance as well as therapeutic efficacy. Because of their low cost, greater stability, non-toxicity, biocompatibility, non-immunogenicity, and biodegradability, these are considered superior drug delivery systems. In this study, a site-specific periodontal drug delivery system for Metronidazole and Minocycline HCl was developed. The augmented fibre formulation G-II laterally with scaling and root planning was effective in eliminating local irritants, reducing gingival inflammation, reducing pocket depth, and increasing clinical addition. Method (A) revealed a determined drug release of 81.8 percent over a period of 120 hours, while method (B) released 84 percent drug(s) over a period of 264 hours. For the optimized formulation, the value of n is assumed to be 0.9314 and follows zero-order. It also measured the restricted infection and prevented the formation of new lesions. In the current revision, there was a significant decrease in mean plaque index, gingival index, sulcus bleeding index, and probing pocket depth, as well as a significant increase in clinical affection. The current study's local drug delivery system is artless and simple to use.
Phytochemical screening and in vitro anticancer activity of ethyl acetate fraction of seagrass Halodule uninervis from Mandapam coastal region, Rameswaram, Gulf of Mannar, India
Authors: PARTHASARATHI PERUMAL , UMAMAHESWARI ARTHANARI , BANUPRIYA RAVICHANDRAN , ELUMALAI SANNIYASI
Published: June 2022

Seagrasses are one of the groups of marine angiosperms widely distributed all over the coastal regions. The seagrass ecosystem is very productive and traditionally used for a variety of therapeutic purposes. The present study aimed to investigate the in-vitro anticancer activity against malignant melanoma (A375), lung carcinoma (A549), cervix adenocarcinoma (HeLa) and colorectal adenocarcinoma (HT29) cell lines and phytochemical screening of ethyl acetate fraction of Halodule uninervis (EAF) from Mandapam coastal region, Rameswaram, Gulf of Mannar, India. The qualitative phytochemical analysis of EAF was performed as followed by standard methods. EAF showed the presence of alkaloids, steroids, terpenoids, flavonoids, phenols and quinones. The total flavonoid and phenolic contents of EAF were determined using the spectrophotometric method. The total flavonoid and phenolic contents showed 67.33 ± 1.52 mg QE/g dried fraction and 87.75 ± 1.39 mg GAE/g dried fraction, respectively. Gas Chromatography-Mass Spectrometry (GC-MS) analysis of EAF shows the presence of 23 phytochemical compounds. The in-vitro anticancer activity of EAF was evaluated by the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay, AO/EtBr staining and DNA fragmentation assay for 24 hours treatment. The IC50 values of EAF showed 91.64 ± 1.61 μg, 269.16 ± 5.17 μg, 845.16 ± 36.09 μg and >1000 μg against A549, HeLa, HT29 and A375 cells, respectively. Followed by reference standard, Doxorubicin showed IC50 values of 17.53 ± 0.07 μg, 14.12 ± 0.30 μg, 17.44 ± 0.25 μg and 21.44 ± 0.40 μg against A549, HeLa, HT29 and A375 cells, respectively. AO/EtBr and DNA fragmentation assay confirmed the occurrence of apoptosis in the A549 cell line after the treatment of EAF. These results suggest that H. uninervis is a promising source of cytotoxicity against A549 cells and could be considered as a source for new lead structures to the development of new anticancer drugs.
Volumen I - Poder nacional de Colombia: la seguridad multidimensional frente a amenazas y desafíos
Authors: Pastrana Buelvas Eduardo , Reith Stefan , Cabrera Ortiz Fabricio
Published: June 2022

La obra se compone de dos volúmenes, a través de los cuales se lleva a cabo un amplio y detallado estudio sobre los recursos y las capacidades de poder que posee Colombia de cara a la tarea de confrontar los factores que constituyen amenazas y desafíos para su seguridad multidimensional. El trabajo es el resultado de procesos de investigación cooperativos entre oficiales activos y oficiales de reserva de las Fuerzas Militares de Colombia, así como también de profesores investigadores de distintas universidades del país y tomadores de decisión de los sectores público y privado. En su gran mayoría, los autores produjeron sus contribuciones en el marco del Curso de Altos Estudios Militares (CAEM) y el Curso Integral de Defensa Nacional (CIDENAL) de la Escuela Superior de Guerra General Rafael Reyes Prieto.
Volumen II - Poder nacional de Colombia: la seguridad multidimensional frente a amenazas y desafíos
Authors: Pastrana Buelvas Eduardo , Reith Stefan , Cabrera Ortiz Fabricio
Published: June 2022

La obra se compone de dos volúmenes, a través de los cuales se lleva a cabo un amplio y detallado estudio sobre los recursos y las capacidades de poder que posee Colombia de cara a la tarea de confrontar los factores que constituyen amenazas y desafíos para su seguridad multidimensional. El trabajo es el resultado de procesos de investigación cooperativos entre oficiales activos y oficiales de reserva de las Fuerzas Militares de Colombia, así como también de profesores investigadores de distintas universidades del país y tomadores de decisión de los sectores público y privado. En su gran mayoría, los autores produjeron sus contribuciones en el marco del Curso de Altos Estudios Militares (CAEM) y el Curso Integral de Defensa Nacional (CIDENAL) de la Escuela Superior de Guerra General Rafael Reyes Prieto.
Impacts of Perceived Justice and Emotional Intelligence on Organizational Commitment and Organizational Citizenship Behavior
Authors: Thoa Nguyen Thi , Trang Tieu Van , Kim Ba Nguyen Thi , Nhi Bui Thi , Nam Tran The
Published: June 2022

How to motivate employees to commit to the organization and to have more voluntary, beneficial behaviors for the organization is an interesting topic for researchers and managers. Based on the theory of equity, authors analyze the impacts of perceived justice and emotional intelligence on employees’ organizational commitment and organizational citizenship behaviors. The mixed research method is used to build a research model and to verify hypotheses with the data of 171 respondents working in different industries which deal with customers in HCM city. The partial least squares structural equation modeling (PLS-SEM) is used in order to explore the impacts of the two high order construct: Emotion intelligence and perceived justice on the organizational commitment, then onto organizational citizen behavior (OCB). The research results pointed out that all hypotheses are accepted. Perceived justice has greater impacts on employees’ organizational commitment than emotional intelligence. In contrast, emotional intelligence has greater influences on employees’ OCB than perceived justice. Managers should establish clear working process, offer opportunities for employees to express their feelings and recognize exactly employees’ contributions in order to improve the employees’ perception of fairness. Selecting carefully candidates and providing training programs are best ways to increase employees’ emotional intelligence.
Teachers' opinions on (urgent) distance education activities during the pandemic period
Authors:   Faculty of Education, Anadolu University, Eskişehir, Turkey, Can Yafes , Bardakci Salih ,   Faculty of Education, Tokat Gaziosmanpaşa University, Tokat, Turkey
Published: June 2022

The purpose of this study is to understand teachers' experiences in-depth on distance education activities held urgently during the pandemic and holistically reveal them. For this purpose, the interlocking single event pattern from case study designs was used to have depth meanings from the teachers' views. In the study, a semi-structured questionnaire was created as a data collection tool and applied to sixty-six teachers with snowball sampling. Teachers participating in the study generally work at primary, secondary and high schools. At the end of the study, it was revealed that the interaction between students, student-teacher, and teacher-parent in urgent distance education processes was generally insufficient; there was no socialization. In addition, it was revealed that both teachers and students experienced various positive and negative emotions, the teaching content was insufficient, and there was a lack of technological equipment and knowledge. However, as an alternative, urgent education activities had some positive aspects for the teachers. As a result of the study, it is recommended to design distance education better, provide a better communication channel between teacher-student-parent, eliminate technological infrastructure problems, and provide technical and psychological support to teachers during urgent distance education practices.
Sistemas de costos ABC: Modelo aplicado a una unidad funcional de laboratorio clínico
Authors: Moncada Rendon Juan Carlos , Sabogal Pinilla José Reinaldo , Gil Zuleta Carlos Alberto
Published: June 2022

En el desarrollo de esta investigación, se aplicó una metodología con un enfoque cuantitativo, el cual busca, a partir de unas cifras evidenciadas en la actividad estudiada, realizar un análisis e interpretación a cada uno de los indicadores que hacen parte de los costos ABC; igualmente, desde un método de estudio deductivo basado en la observación directa y la información aportada por las empresas de servicio, con un tipo de estudio descriptivo, se logra identificar y describir la información relevante para la toma de decisiones. Con el resultado de esta investigación no solo los laboratorios se verán beneficiados con el reordenamiento de los procesos internos en las áreas de contabilidad, compras, etc., sino también los usuarios en general, debido a que, si se logra disminuir el costo del servicio con este sistema, las tarifas lo harán de manera proporcional. Con este trabajo se contribuirá, además, al desarrollo de estas entidades y se complementarán los conceptos teóricos de los estudios de costos ABC. La importancia de su aplicación radica en que permite determinar el costo de la ejecución de los servicios e identificar el dinamismo de cada una de las actividades, buscando siempre minimizar todos los factores que no añaden valor a la actividad y, por ende, al proceso, pero que de igual forma son generadores de costos; logrando así tener bases idóneas para tomar decisiones en el momento de eliminar, mantener o mejorarlas para la prestación de los servicios.
Access to Treatment and Cultural Use for People Living with HIV and AIDS (PLWHA) During the COVID-19 Pandemic in the Special Region of Yogyakarta, Indonesia: An Anthropological Approach
Authors:   Department of Anthropology, Universitas Gadjah Mada, Indonesia, Taher Muhammad Dian Saputra , Triratnawati Atik ,   Department of Anthropology, Universitas Gadjah Mada, Indonesia
Published: June 2022

During the COVID-19 pandemic, people living with HIV and AIDS (PLWHA) experienced various problems related to the continuity of treatment because lockdowns hamper their drug supplies. This study examined PLWHA’s access to treatment to maintain their health during the COVID-19 pandemic, associated with traditional medicine well-known to Javanese people in Yogyakarta. Qualitative research was conducted in 2020 with online and offline focus group discussions and offline interviews with PLWHA from two NGOs in Yogyakarta, Indonesia. People living with HIV and AIDS had problems getting their medicine on time due to the limited availability. Drugs for a 30-day use were only enough for 15 days or even 10 days, especially at the beginning of the COVID-19 pandemic. They dealt with these drug supply delays jointly with other PLWHA borrowing drugs. To maintain their immunity, besides consuming vitamins, they also used Javanese herbal medicine they believed was effective for maintaining body fitness and immunity, and as alternative medicine besides medical drugs. The culture of Javanese people in Yogyakarta, who have long known herbal medicine contributes to shaping the PLWHA’s view, found that they will turn to herbal medicine to improve immunity.
Vaccination against human papillomavirus after adjuvant therapy of cervical intraepithelial neoplasia
Authors: Kutsenko I. I. , Borovikov I. O. , Tomina O. V. , Gorring H. I. , Bulgakova V. P. , Borovikova O. I.
Published: June 2022

Background. The relevance of the problem is supported by the lack of effective secondary prevention measures against human papillomavirus (HPV)-associated cervical intraepithelial neoplasia (CIN) and cervical cancer. The only currently verified treatment for lower genital neoplasia is destructive therapy, with the recurrence rate of viral infection remaining quite high even after such interventions. The preventive role of HPV vaccine at pre-existing cervical lesions is actively debated worldwide, but the evidence remains scattered and contradictory. The present study surveys the scientific publications available that evaluate the efficacy of human papillomavirus vaccination as a secondary prevention measure against related cervical pathology.Objectives. An evidence survey on the efficacy of adjuvant vaccination against human papillomavirus in patients undergoing destructive therapy for cervical intraepithelial neoplasia.Methods. We have conducted a 10 year-depth review of scientific literature on the adjuvant human papillomavirus (HPV) vaccination efficacy for reducing the recurrence risk of precancerous cervical neoplasia. The results are presented in form of the difference of mean or pooled 95% confidence-interval odds ratios (OR; 95% CI). Statistical analyses were conducted with Review Manager v. 5.4 (The Cochrane Collaboration, 2020).Results. Thirteen Russian- and English-language studies were selected for final analysis. A total of 21,702 cervical dysplasia patients were included: 5,941 (27.4%) received a perioperative HPV vaccine, while 15,761 (72.6%) only had surgical treatment. Recurrences of CIN I (mild cervical intraepithelial neoplasia; OR 0.45, 95% CI 0.27–0.73; p = 0.001) and CIN II (moderate cervical intraepithelial neoplasia; OR 0.33, 95% CI 0.20–0.52; p <0.0001) were lower in the vaccinated vs. unvaccinated cohort.Conclusion. Adjuvant HPV vaccination associates with a lower risk of recurrence in cervical intraepithelial neoplasia. Further research is necessary to shed more light on the role of human papillomavirus vaccination as a secondary prevention measure against its associated lesions.
Scrotal variceal bleeding during rivaroxaban therapy as alarming sign in senescent patients: A clinical case
Authors: Chepurnenko S. A. , Shavkuta G. V. , Nasytko A. D.
Published: June 2022

Background. The past decade has witnessed the advent of direct oral anticoagulants (DOACs) into clinical practice for the prevention and treatment of venous thromboembolism, as well as stroke prevention in atrial fibrillation (AF) patients. A serious complication of anticoagulant treatment is bleeding. Randomised controlled trials have shown that the risk of already developed bleeding does not reduce upon a DOAC replacement. In such cases, the bleeding cause diagnosis and elimination are recommended instead of a anticoagulant replacement. An anticoagulant treatment can only be resumed once the elimination is completed.Clinical Case Description. Patient K., 81 yo, was emergently admitted to a cardiology ward of the Rostov Regional Clinical Hospital with a clinical picture of bilateral pulmonary embolism of small arterial branches confirmed in multislice computed angiopulmonography. Apart from venous embolism, persistent atrial fibrillation was detected as an additional indication for DOAC treatment. A CHA2DS2-VASc risk of thrombosis was 6, HAS-BLED risk of bleeding — 2. Glomerular filtration rate at bleeding was 90 mL/min/1.73 m2. The patient was prescribed rivaroxaban at 20 mg daily. Past 2 years and 3 months, rivaroxaban has been withdrawn due to bleeding developing from scrotal veins. An urologist examination revealed a bilateral spermatic cord veins dilation. A Valsalva test revealed persistent retrograde veinous blood flow. Varicocele detected on both sides.The patient underwent venous occlusion of left internal spermatic vein following an Ivanissevich procedure. The cause of bleeding was eliminated. The patient resumed rivaroxaban 1 week since the operation.Conclusion. The case describes a rare cause of bleeding that has been established at a continued new DOAC therapy.
Approximation of periodic solutions of two-mode phase-field crystal model
Authors: Анкудинов Владимир Евгеньевич , Стародумов Илья Олегович
Published: June 2022

В работе рассмотрена двухмодовая математическая модель кристаллического фазового поля (КФП), описывающая микроскопическую структурную динамику и упорядочение вещества в процессе кристаллизации из однородной фазы. Модель представлена нелинейным дифференциальным уравнением десятого порядка по пространству и второго по времени, для решения которого был применен метод конечных элементов Галеркина.

В силу периодического вида численных решений потребовалось учитывать дополнительный пространственный масштаб, уменьшая размеры элемента для повышения точности вычисления производных. Высокая вычислительная сложность двухмодовой модели КФП нацелила на исследование сходимости решений на сетке и определение критериев дискретизации. Рассмотрено влияние размеров конечных элементов (КЭ) и порядка их базовых функций на аппроксимацию решения в пределах конечного элемента для случая движения плоского фронта кристаллизации. Определены оптимальные размеры КЭ, выполнено сравнение эффективности расчетов при использовании различных программных пакетов и решателей.
ANALISIS PIDATO CALON GUBERNUR Dr. H. SOEKARWO TAHUN 2008 APBD UNTUK RAKYAT WUJUDKAN JAWA TIMUR MAKMUR DAN BERAKHLAK
Authors: Cendriono Nanang
Published: June 2022

Pada sebuah teks (wacana), terbaca keberpihakan, hegemoni, marginalisasi, dominasi, dan objeknya. Pidato tokoh biasanya menggunakan bahasa yang bersifat komunikatif, unik dan menarik. Hal ini dilakukan agar orang-orang yang mendengar merasa terpesona akan pidatonya. Penelitian ini merupakan penelitian kualitatif yang bersifat deskriptif dengan pendekatan pragmatik. Data dalam penelitian ini berupa kutipan-kutipan kalimat atau ungkapan-ungkapan yang mengandung implikatur yang mengarah pada prinsip kerjasama serta isi yang terdapat pada visi misi pidato Calon Gubernur Dr. Soekarwo pada tahun 2008. Adapun sumber data penelitian ini adalah pidato Dr. Soekarwo pada penyampaian visi misi Calon Gubernur Jawa Timur tahun 2008. Teknik pengumpulan datanya adalah teknik dokumentasi. Analisis data menggunakan tiga langkah yaitu 1) meninjau dan mencermati hasil catatan yang telah didapatkan dalam proses lapangan yang berupa kutipan-kutipan tuturan kalimat pidato pada saat penyampaian visi misi Calon Gubernur Jawa Timur Dr. Soekarwo, 2) memberi kode pada bagian-bagian ujaran kalimat pada saat penyampaian visi misi yang dianggap penting, 3) menyimpulkan makna yang terdapat di dalam isi pidato Dr. Soekarwo pada saat penyampaian visi misi. Wacana Pidato calon Gubernur Dr. H. Soekarwo ingin membuat Jawa Timur makmur dan berakhlak. Sebagai dokumen politik, program ini merupakan pertanggungjawaban awal di hadapan rakyat Jawa Timur.Dengan kesadaran bahwa Jawa Timur merupakan Propinsi yang memiliki keanekaragaman sosial budaya, ekonomi dan politik, sungguh Jawa Timur adalah miniatur Indonesia, sebagai kekayaan bangsa yang tidak terpermaknai, memiliki kekayaan alam yang memadai, memiliki modal sosial yang besar dan panutan atas nasionalisme yang teguh.
MENINGKATKAN KEMAMPUAN MENULIS PARAGRAF NARASI MELALUI MEDIA BUKU HARIAN PADA SISWA KELAS VII MTsN SARADANKABUPATEN MADIUN
Authors: Ayuningrum Iis Dyah
Published: June 2022

Penelitian ini dilatarbelakangi oleh adanya permasalahan-permasalahan yang sering muncul dalam pengajaran bahasa Indonesia dalam pembelajaran menulis, khususnya kemampuan menulis paragraF narasi melalui media buku harian. Kemampuan menulis merupakan kemampuan berbahasa yang sangat kompleks dan menuntut sejumlah kemampuan berbahasa dan senantiasa melatih kita berpikir kritis dan logis. Dapat tidaknya suatu pesan seseorang dipahami oleh orang lain membutuhkan suatu kelengkapan, kesatuan, dan kepaduan, khususnya kepaduan dalam puisi. Penelitian ini bertujuan untuk mengetahui bagaimana peningkatan kemampuan menulis puisi bahasa Indonesia dengan menggunakan media buku harian dilakukan dengan penelitian tindakan kelas (PTK).

PTK ide awalnya ialah terdapatnya suatu permasalahan yang berlangsung di dalam suatu kelas. Ide awal tersebut di antaranya berupa suatu upaya yang dapat ditempuh untuk mengatasi permasalahan. Dengan penerapan PTK seseorang pelajar mau berbuat apa saja demi perubahan dan perbaikan. PTK juga dapat menentukan berbagai hal, misalnya metode pengajaran, media pengajaran, dan materi pengajaran yang tepat dalam kaitannya dengan implementasi PTK.

Desain penelitian menggunakan metode penelitian tindakan kelas. Metode ini adalah model penelitian tindakan kelas (PTK) model Kurt Lewin, langkah yang ditempuh siklus I, siklus II, dan siklus III, sedang tempat penelitian di MTsN Saradan, Kabupaten Madiun. Penelitian ini adalah penelitian populatif yang homogen, ada anak yang pandai, sedang, dan kurang, usia cenderung sama.

Hasil analisis data siklus I cukup baik, dilanjutkan siklus II dan siklus III. Dari tiga siklus yang telah dilaksanakan dalam penelitian prestasi dan keaktifan objek penelitian sudah memuaskan dan sudah memenuhi ketuntasan belajar. Siswa yang berhasil atau tuntas mengalami peningkatan, siklus I mencapai 69%, siklus II mencapai 88% dan pada siklus III mencapai 100%. Dengan demikian dapat disimpulkan bahwa siswa kelas VII MTsN Saradan, Kabupaten Madiun mampu meningkatkan kemampuan menulis paragraf narasi melalui media buku harian.     
PENGARUH STRATEGI PEMBELAJARAN KONTEKSTUAL DAN MOTIVASI BERPRESTASI TERHADAP KOMPETENSI MENULIS DESKRIPSI SISWA SMP KELAS VIII
Authors: Waraulia Asri Musandi
Published: June 2022

Penelitian ini adalah penelitian eksperimen yang bertujuan untuk mengetahui: (1) perbedaan kompetensi penulisan deskriptif siswa antara yang diajarkan dengan strategi pembelajaran kontekstual dan strategi pembelajaran ekspositori; (2) pengaruh  motivasi berprestasi terhadap kompetensi menulis deskripsi, dan (3) pengaruh strategi pembelajaran dan motivasi berprestasi terhadap kompetensi  menulis deskripsi. Penelitian eksperimen ini menggunakan 2x2 desain faktorial. Populasi adalah semua siswa Kelas VIII SMP di Kabupaten Ngawi, dengan sampel adalah 68 siswa di SMP N 1 dan 2 Mantingan Ngawi dengan menggunakan stratified-cluster random sampling. Data penelitian dikumpulkan dengan uji dan kuisioner. Penelitian ini memiliki kesimpulan yakni (1) kompetensi menulis deskripsi siswa  yang diajar dengan strategi kontekstual secara signifikan lebih baik daripada kompetensi menulis deskripsi siswa yang diajar dengan strategi ekspositori; (2) kompetensi menulis deskripsi siswa  yang memiliki motivasi berprestasi tinggi lebih baik daripada kompetensi menulis deskripsi siswa yang memiliki motivasi berprestasi rendah; dan (3) ada interaksi strategi pembelajaran dan motivasi berprestasi terhadap kompetensi menulis deskripsi.
SISTEM NGLIMOLASI SEBAGAI ARENA DALAM NOVEL GENDUK KARYA SUNDARI MARDJUKI
Authors: Ramadha Alif Wahyu , Santoso Agus Budi , Furinawati Yunita
Published: June 2022

 

Salah satu produk interaksi sosial di masyarakat yaitu terdapat arena pada novel Genduk karya Sundari Mardjuki.Novel Genduk yang memiliki latar pertanian tembakau dengan berbagai interaksi sosial yang ada menarik untuk dianalisis dari segi sosiologi sastra.Tujuan penelitian ini adalah mendeskripsikan interaksi sosial yang terdapat pada suatu arena dari segi sosiologi sastra pemikiran Pierre Bourdieu.Penelitian menggunakan metode analisis deskriptif kualitataif dengan teknik analisis dokumen (content analysis) serta pendekatan sosiologi pemikiran Pierre Boudieu. Hasil penelitian yang dilakukan penulis adalah: Arena menunjukkan adanya pertaruhan yang dilakukan petani dalam memperjuangkan tembakau milik mereka dengan sistem ekonomi nglimolasi demi mendapat sokongan dana selama proses pasca panen.
MENGEMBANGKAN KECERDASAN EMOSIONAL SISWA DALAM PEMBELAJARAN SASTRA
Authors: Setyoko Imanudin Hari , Andayani Andayani , Setiawan Budhi
Published: June 2022

Kecerdasan emosional (EQ) adalah salah satu aspek penting yang mempengaruhi keberhasilan siswa pada setiap kegiatan pembelajaran. Kesan pembelajaran yang ada hanya sebatas pengetahuan yang mengarahkan pada pengembangkan ranah kognitif saja tanpa mempertimbangkan ranah afektif dan psikomotor yang dimiliki siswa. Akibatnya, keterampilan siswa jadi tidak seimbang. Tanpa disadari, kecerdasan emosional justru memiliki peran dalam membentuk keterampilan dan perilaku belajar siswa. Salah satu pembelajaran yang dapat membangun kecerdasan emosional siswa adalah cerpen, karena harus melibatkan unsur-unsur perasaan dan emosi mereka. Tujuan penelitian ini adalah untuk membangun pemahaman mendalam guru tentang pentingnya membangun kecerdasan emosional siswa pada kegiatan pembelajaran. Penelitian ini menggunakan metode kualtitaif untuk menjawab permasalahan yang ada. Hasilnya, dalam penelitian ini ditemukan perubahan persepsi guru tentang pentingnya membangun kecerdasan emosionalsiswa. Adanya perubahan perilaku belajar siswa menjadi lebih bersemangat mengikuti kegiatan pembelajaran juga menjadi salah satu hasil dalam penelitian ini.

 
MULTIPLE INTELLIGENCES: OPTIMALISASI KEGIATAN PEMBELAJARAN BAHASA INDONESIA BERBASIS 8 KECERDASAN
Authors: Ayuningrum Iis Dyah
Published: June 2022

Pendidikan adalah kunci terpenting untuk membentuk masyarakat yang lebih berkualitas. Permasalahan yang ada di dunia pendidikan masih pada pengelolaannya yang berantakan. Kondisi pembelajaran masih berjalan satu arah, guru mengklaim dirinya menjadi satu-satunya sumber belajar yang paling benar dan tidak ada inovasi baru dari kegiatan pembelajaran yang terlaksana. Multiple intelligences adalah salah satu inovasi yang harus dilaksanakan di dalam kegiatan pembelajaran. Teori kecerdasan yang dicetuskan oleh Howard Gardner ini dianggap efektif untuk menyempurnakan proses pembelajaran. Tujuan dari penelitian ini adalah untuk mengoptimalkan kegiatan pembelajaran berbasis delapan kecerdasan. Metode kualitatif dianggap mampu menjawab pertanyaan yang muncul pada penelitian ini. Hasilnya, dalam penelitian ini menunjukkan bahwa siswa bersemangat mengikuti kegiatan pembelajaran, dan pemahaman guru tentang batasan pada istilah siswa ‘pandai-bodoh’ terbangun.
ANALISIS PERISTIWA TUTUR DENGAN METODE SPEAKING (SETTING AND SCENE, PARTICIPANTS, ENDS, ACT SEQUENCES, KEY, INSTRUMENTALITIES, NORM OF INTERECTION AND INTERPRETATION, GENRES) DALAM ACARA TALK SHOW MATA NAJWA DI TRANS7
Authors: Hartini Ayu Fri , Hadi Panji Kuncoro , Waraulia Asri Musandi
Published: June 2022

Penelitian ini bertujuan untuk mendeskripsikan dan menjelaskan  peristiwa tutur dengan metode SPEAKING yang terdapat dalam acara talk show mata najwa di trans7 dan mendeskripsikan serta menjelaskan persamaan dan perbedaan peristiwa tutur yang terdapat dalam acara talk show mata najwa pada setiap episodenya. Penelitian ini dilakukan pada April 2019 dengan fokus kajian peristiwa tutur dalam acara talk show mata najwa. Metode penelitian yang dipakai adalah metode kualitatif. Teknik penumpulan data dalam penelitian ini adalah metode simak bebas libat cakap. Data penelitian ini adalah peristiwa tutur dalam acara talk show mata najwa pada April dengan mengambil 4 episode yang tayang pada tanggal 3, 10, 17, dan 24 April 2019. Berdasarkan permasalahan serta pembahasan yang telah dilakukan oleh peneliti, maka penelitian pada acara talk show mata najwa sudah memenuhi syarat peristiwa tutur yang sesuai dengan rumusan masalah yang dikaji oleh peneliti. Peristiwa tutur dalam acara talk show mata najwa pada episode debat usai debat, Jokowi atau Prabowo, suara penentu, dan usai pemilu ini, pada hasil analisis yang diteliti sudah memenuhi syarat peristiwa tutur SPEAKING (setting and scene, participants, ends, act sequences, key, instrumentalities, norm of interection, and interpretation, genres). Persamaan dan perbedaan peristiwa tutur pada setiap episode berdasarkan hasil analisis peristiwa tutur tersebut terdapat 7 persamaan dan 3 perbedaan. Berdasarkan hasil tersebut, dapat disimpulkan bahwa keseluruhan setiap episode pada April 2019 sudah memenuhi syarat peristiwa tutur dan dari keempat episode tersebut terdapat 7 persamaan dan 3 perbedaan.
INTERFERENSI BAHASA INDONESIA PADA ACARA “MY TRIP MY ADVENTURE” DI TRANS TV EDISI BULAN MARET TAHUN 2019 (KAJIAN SOSIOLINGUISTIK)
Authors: Nurhana Gita , Soleh Dwi Rohman , Winarsih Eni
Published: June 2022

Penelitian ini bertujuan untuk mendeskripsikan bentuk interferensi bahasa Indonesia pada acara My Trip My Adventure edisi bulan Maret 2019. Selain itu, untuk mendeskripsikan penyebab terjadinya interferensi bahasa Indonesia pada acara My Trip My Adventure edisi bulan Maret 2019. Penelitian ini dilakukan pada bulan Maret 2019 dan menganalisis sebanyak lima episode acara TV My Trip My Adventure. Penelitian ini menggunakan pendekatan kualitatif dan metode yang digunakan dalam penelitian ini adalah metode deskriptif. Sumber data dalam penelitian ini diperoleh dari acara TV My Trip My Adventure. Teknik pengumpulan data pada penelitian ini berupa pengumpulan data observasi nonpartisipasi (no involvement). Teknik analisis data menggunakan content analisis melalui tahap reduksi data, penyajian data, serta penarikan kesimpulan. Hasil penelitian ini menunjukkan inteferensi yang terdapat dalam acara My Trip My Adventure adalah interferensi fonologi yang ditemukan berjumlah 19 data, kemudian interferensi morfologi yang ditemukan berjumlah 13 data, dan interferensi sintaksis berjumlah 35 data. Penyebab terjadinya interferensi bahasa Indonesia pada acara My Trip My Adventure adalah yang pertama karena keterbatasan kemampuan penutur dalam berbahasa Indonesia, dan yang kedua karena kedwibahasaan penutur.
PENGUASAAN ASPEK FONOLOGI DAN LEKSIKON ANAK PENYANDANG TUNAGRAHITA DI SLB DHARMA WANITA
Authors: Mubarrok Hafidh , Suharto Teguh , Puspitasari Dhika
Published: June 2022

Penelitian ini bertujuan untuk (1) Mendeskripsikan mengenai penguasaan fonologi pada anak penyandang Tunagrahita di Sekolah Luar Biasa Dharma Wanita Kebonsari Madiun, dan (2) Mendeskripsikan mengenai penguasaan leksikon pada anak penyandang Tunagrahita di Sekolah Luar Biasa Dharma Wanita Kebonsari. Penelitian ini dilakukan kurang lebih selama 7 bulan.

Metode yang digunakan pada penelitian ini adalah metode penelitian deskriptif kualitatif. Jenis penelitian yang digunakan pada penelitian ini yaitu studi kasus. Data yang digunakan dalam penelitian ini, yaitu berupa anak penyandang tunagrahita di SLB Dharma Wanita.

Hasil dari penelitian ini ditemukan bahwa, pemerolehan fonologi anak penyandang tunagrahita pada  tahap ini anak sudah mampu menghasilkan fonem vokal dan diikuti fonem konsonan. Pemerolehan fonologi sudah dihasilkan anak penyandang tunagrahita yaitu Bahasa Indonesia dan Bahasa Jawa. Fonem Bahasa Indonesia yaitu fonem vokal /a/, /i/ /u/, /e/, /o/, /ǝ/ dan konsonan /b/, /c/, /d/, /f/, /g/, /h/ /j/, /k/, /l/, /m/, /n/, /p/, /r/, /s/, /t/, /w/, /y/, /ŋ/, /ň/. Sedangkan fonem Bahasa Jawa yaitu fonem vokal /a/, /i/ /u/, /e/, /o/, /ǝ/ dan fonem konsonan /b/, /c/, /d/, /g/, /h/ /j/, /k/, /l/, /m/, /n/, /p/, /r/, /s/, /t/, /v/, /w/, /y/, /ŋ/, /ň/, /ḑ/. Pemerolehan leksikon yang sudah dihasilkan oleh anak penyandang tunagrahita yaitu leksikon Bahasa Indonesia dan leksikon Bahasa Jawa. Di mana anak penyandang tunagrahita sudah mampu menghasilkan kelas kata Bahasa Indonesia yaitu kata benda, kata sifat, kata kerja, kata bilangan, kata ganti, kata keterangan, kata depan, dan kata hubung. Sedangkan kelas kata Bahasa Jawa yaitu kata benda, kata sifat, kata kerja, kata bilangan, kata ganti, kata keterangan, dan kata depan.
TEKS, KOTEKS, KONTEKS PADA SURAT KABAR BANTEN EKSPRES FEBRUARI 2020
Authors: Goziyah Goziyah , Wardhani Igasa Aditya , Titania Diah Ayu
Published: June 2022

Analisis wacana kritis merupakan metode analisis yang dapat menghantarkan pada pemahaman wacana yang benar. Di antara aspek yang menentukan kesahihan analisis wacana adalah dengan memanfaatkan aspek teks, ko-teks, dan konteks wacana. Penelitian ini bertuijuan untuk mendeskripsikan aspek teks, ko-tek, dan konteks yang terdapat pada kolom Ayo Sekolah pada surat kabar Banten Ekspres. Metode penelitian ini adalah penelitian kualitatif, data teks diambil dari surat kabar harian Banten Ekspres pada hari Jumat tanggal 21 Februari. Teks diambil dari kolom Ayo Sekolah pada surat kabar Banten Ekspres. Kemudian data dianalisis dengan teknik analisi isi, dan disajikan secara informal bebas. Hasil penelitian menunjukkan bahwa wacana yang dianalaisis merupakan teks. Sedangkan aspek ko-teks memngaruhi pemahaman teks wcana yang berupa kalimat kalimat atau tuturan yang mendahului dan mengikutinya yang mendukung arti teks sesudah atau sebelumnya. Aspek konteks yang memengaruhi pemahaman wacana pada kolom Ayo Sekolah adalah berupa konteks situasi.
ANALISIS FUNGSI TINDAK TUTUR GURU DAN SISWA DI TK YUNIOR MANYAR REJO, KELURAHAN MENUR PUMPUNGAN KECAMATAN SUKOLILO SURABAYA
Authors: Pratama Okky Indra , Utami Sri , Huda Nuril
Published: June 2022

Tindak tutur merupakan suatu kajian ilmu yang dibahas dalam pragmatik yang melibatkan pembicara, pendengar ataupun penulis, pembaca serta yang dibicarakan. Sedangkan pragmatik sendiri merupakan kajian dalam ilmu linguistik yang membahas terkait makna dan maksud serta penafsiran tuturan seorang mitra tutur. Dalam penelitian ini, bertujuan untuk menganalisis suatu “Fungsi Tindak Tutur Guru dan Siswa di TK Yunior Manyar Rejo, Kelurahan Menur Pumpungan Kecamatan Sukolilo Surabaya”. Penelitian ini membahas terkait fungsi tindak tutur yang meliputi fungsi asertif, komisif, direktif, ekspresif, dan deklaratif. Pengumpulan data dalam penelitian ini yakni menggunakan metode simak bebas libat cakap dengan cara melakukan perekamanperistiwa pertuturan guru dan siswa dalam kegiatan pembelajaran dengan alat berupa handphone, dan metode simak libat cakap yakni dalam melakukan bentuk wawancara kepada guru kelas TK B dan kepala sekolah untuk mendapatkan data pendukung. Berdasarkan hasilpenelitian yang telah dilakukan, maka didapatkan data fungsi tindak tutur asertif yakni berupa tuturan melaporkan, pernyataan, menyarankan, dan menawarkan, fungsi tindak tutur komisif yakni berupa tuturan mengusulkan sesuatu, fungsi tindak tutur direktif yakni berupa tuturan memerintah, menasihati, melarang, mengajak, dan menyarankan, fungsi tindak tutur ekspresif yakni berupa tuturan ucapan terima kasih, ucapan selamat, pujian, kritikan, dan permohonan maaf dan fungsi tindak tutur deklaratif yakni berupa tuturan menghukum dan menetapkan.