bluuebunny/crossref_metadata_2025 huggingface dataset:
UNIÃO HOMOAFETIVA, BACKLASH E O ACORDO DE PAZ COM AS FARC
Authors: Cardoso Farias Marina
Published: November 2020

Em 2016, a Corte Constitucional colombiana reconheceu o casamento entre pessoas do mesmo sexo. A decisão culminou em um backlash da parcela mais conservadora da população, chegando a influenciar inclusive no plebiscito instaurado no país alguns meses depois acerca do acordo de paz entre o governo e as FARC. O objetivo do trabalho é o ligar as ideias de ativismo judicial, backlash e constitucionalismo democrático, se utilizando do método de procedimento de estudo de caso, com base no caso colombiano de 2016. Questiona-se se o backlash e suas consequências seriam uma manifestação dos problemas que envolvem o ativismo judicial, ou se seriam benéficos para a consolidação do constitucionalismo democrático. O que se conclui dessa análise é que o backlash a decisões polêmicas das cortes, inevitáveis num contexto de ativismo judicial, pode ter efeitos significativos na sociedade, como a influência no processo de paz colombiano. No entanto, o engajamento público, ainda que contrário, não deixa de ser um elemento importante na condução e legitimação do judicial review.
OS LIMITES DA DESCONSIDERAÇÃO DA PERSONALIDADE JURÍDICA
Authors: Rocha Gustavo Ribeiro
Published: November 2020

O presente trabalho apresenta, a partir da Lei, da doutrina e jurisprudência nacionais, algumas importantes características do instituto da desconsideração da personalidade jurídica no Direito brasileiro, especialmente em seu aspecto material, visando à sua adequada compreensão, para aplicação casuística. Para tanto, o presente trabalho propõe a observação das dificuldades em se chegar a um conceito objetivo, bem como os desafios de diferenciá-la de outras medidas jurídicas, tais como a dissolução da sociedade, a responsabilidade ilimitada de sócio e a responsabilidade de administrador por atos culposos ou dolosos, insolvência ou inexistência de bens, até sua adequada aplicação em casos concretos. Com este trabalho espera-se contribuir para os estudos da teoria da desconsideração da personalidade jurídica e tratamentos mais adequados à sua aplicação no Direito brasileiro, a partir do texto legal, da doutrina e da jurisprudência nacionais, visando evitar sua inadequada aplicação, que pode levar ao seu uso abusivo e indiscriminado, que pode até mesmo levar tal instituto ao descrédito.
Código Florestal Brasileiro, agricultura familiar e assentamentos rurais
Authors: Totti Guimarães Virgínia , Chermont Pessoa Lopes Juliana , Máximo de Barros Pinto Paula
Published: November 2020

O presente trabalho visa analisar as normas do Código Florestal de 2012 aplicáveis aos agricultores familiares e, ainda, aos assentamentos rurais. A metodologia baseia-se em pesquisa e análise crítica da bibliografia, bem como levantamento de dados específicos relativos ao Cadastro Ambiental Rural. As peculiaridades do tratamento destinado aos assentamentos rurais no processo de inscrição no Cadastro Ambiental Rural (CAR) são analisadas, objetivando-se apresentar questionamentos sobre os direitos e garantias dos assentados decorrentes desse cadastramento. O trabalho traz reflexões acerca das Cotas de Reserva Ambiental originárias de assentamentos rurais. Verificou-se que, no que se refere ao CAR, a maioria das regras específicas sobre assentamentos rurais direciona-se à simplificação dos procedimentos, mas não houve previsão sobre a necessária participação dos assentados na geração das informações a serem incluídas no Cadastro, bem como a garantia de amplo acesso aos estudos e dados produzidos no âmbito do INCRA. No que se refere aos pagamentos por serviços ambientais, além dos debates relativos a mercantilização da natureza, não há sequer menção sobre as cotas originadas de excedentes de vegetação nativa em assentamentos rurais, o que gera uma série de questionamentos a respeito dos direitos garantidos nos procedimentos estabelecidos pelo Código Florestal.
Apresentação
Authors: Souza Costa Beatriz , Santos Rocha Anacélia , Jorge Sobral de Brito Franclim
Published: November 2020

Apresentação Vol. 1, n.1, Set./Dez. 2018
ANÁLISE JURÍDICO-FILOSÓFICA DO SACRIFÍCIO DE ANIMAIS NÃO HUMANOS NO CANDOMBLÉ
Authors: Moreira da Silva Pedro Henrique
Published: November 2020

O estudo pretende suscitar a questão do conflito entre liberdade religiosa e direito animal, no que tange ao sacrifício de animais não-humanos nos cultos de Candomblé – religião de matriz africana. Recorrendo ao método hipotético-dedutivo e à pesquisa bibliográfica, buscar-se-á uma análise da temática pelas perspectivas do Direito e da Filosofia, sem furtar-se da consideração dos aspectos éticos, sociais, étnicos, teológicos e do ordenamento jurídico internacional. Isto é, ao mesmo tempo em que os animais não-humanos serão apresentados nas perspectivas dos princípios da dignidade – que decorrem das noções de “outridade” – também serão consideradas as dimensões da liberdade religiosa e a necessidade de coesão sociocultural para fortalecimento do debate. Nesse sentido, justifica-se a pesquisa pela complexidade do tema e em razão do futuro julgamento da pauta pelo Supremo Tribunal Federal – que mais que recorrer às jurisprudências estrangeiras, também deve se preocupar com a as dimensões filosóficas e teológicas que envolvem a causa religiosa e animal.
UM NOVO MODUS VIVENDI BASEADO EM “VIDAS SECAS”
Authors: Rocha Ana Carolina de Mari
Published: November 2020

Os direitos humanos são analisados à luz da obra literária Vidas Secas visando compreender questões socioambientais e culturais envolvidas no sertão nordestino brasileiro que perduram até hoje. Busca-se descortinar a realidade de esquecimento e enfatizar o tempo em que acontecem, e assim demonstrar a atemporalidade da história. O problema consiste na indagação acerca da possibilidade de uma hermenêutica jurídico-social atual por meio da obra de Graciliano Ramos escrita em 1938. O estudo tem os ideais de “solidariedade” de Zygmunt Bauman e “outridade” de Enrique Leff como marcos teóricos principais. Além disso, a ideia de “alteridade” trabalhada por Emmanuel Levinas foi utilizada como referencial teórico subsidiário. Utiliza-se pesquisa doutrinária, de maneira analítico-descritiva, para concluir sobre a atemporalidade do texto e a emergência da necessária formação de um padrão de outridade em relação à região sertaneja, e a outras igualmente esquecidas, que necessitam de uma ressignificação coletiva capaz de transformar seus moradores em verdadeiros atores sociais aptos a transformarem o ambiente em que vivem.
Modern view on LRBA deficiency
Authors: Latysheva Tatyana V. , Latysheva Elena A. , Setdikova Nailya Kh. , Esaulova Daria R.
Published: November 2020

Facilities of molecular genetic methods allow to distinguish several monogenic deficiencies in the general group of primary immunodeficiencies, including common variable immune deficiency (CVID), which have peculiarities of the natural course, therapy, and prognosis. One of these nosologies is LRBA deficiency. In this article a number of foreign sources were reviewed, systematized and classified to define a comprehensive understanding of the LRBA deficiency phenomenon . The most relevant scientific studies of North America and Europe and publications from various ranking medical journals were analyzed.
LRBA deficiency is a PID caused by mutations inLRBAgene that disrupt the immune system regulation. It is characterized by lymphoproliferation, autoaggression, hypogammaglobulinemia and recurrent infections. Sometimes LRBA deficiency is called LATAIE disease (LRBA deficiency with autoantibodies, regulatory T-cell defects, autoimmune infiltration, and enteropathy).
Special attention was given to the mutation ofLRBAgene and the connection to the defects caused in T- and B-lymphocytes, the clinical picture and diagnostics. It was suggested that LRBA protein reduces the level of autophagy, leading to increased apoptosis, impared T- and B-cell immune response, lymphoproliferation and autoimmune disorders. LRBA protein is especially expressed in the immune cells, its deficiency leads to defects of B-cells differentiation. However, LRBA deficiency does not affect T-regulatory cells differentiation. Main approaches to the treatment of patients with LRBA deficiency are presented in the article.
Methods of systemic and content analysis of Russian and foreign sources were used when writing the article.
ADOPTION OF INFORMATION & COMMUNICATION TECHNOLOGY AMONG THE STUDENTS AT TERTIARY LEVEL: BANGLADESH PERSPECTIVES
Authors: Muhammad Abdus Salam  , Trisha Saha  , Tonmoy Dey
Published: November 2020

Information and Communication Technology (ICT) is extensively being used for educational purpose because it helps to make both learning and teaching effective and meaningful. Again, it shrinks the obstacles of habitual learning systems like allowing students to access unlimited educational resources and providing required data timely. Bangladesh has made marvelous betterment in this sector in the last couple of years especially in tertiary level. Now, it is high time to justify how the tertiary level students of Bangladesh are accepting ICT for learning. The study was conducted at the Noakhali Science and Technology University (NSTU) with randomly collected data from 250 students of various departments. It has justified the perceptions, behavior and expectations of tertiary level students towards the adoption of ICT. The results of this study are expected to be useful to the educational policymakers, institutions, educators and the relevant parties.
KEYWORDS: ICT Adoption, ICT in Education, Tertiary Education, NSTU, Bangladesh.
DIFFERENCES IN THE EFFECTIVENESS OF THE DIRECT DEMONSTRATION METHOD AND VIDEO SCREENING OF FIRST AID IN TRAFFIC ACCIDENTS ON THE INCREASE IN KNOWLEDGE OF SENIOR HIGH SCHOOL STUDENTS
Authors: Yusniawati Yustina Ni Putu , Maharyawan I Wayan Agus , Robani Ahmad
Published: November 2020

Background: Traffic accidents are unpredictable collisions among vehicles that might lead to casualties. Injuries due to traffic accidents have killed at least 1.2 million lives per year. Fatalities are high as first aid is not properly administered, causing to higher mortality rate.Objectives: This research compared the effectiveness between the use of live demonstration and videos on high school students’ first aid knowledge.Methods: The research was conducted in the form of a comparative study with a cross sectional approach, for three months, starting from March to June 2019 in Senior High School 1 Rendang Karangasem Bali. The sample taken as many as 150 people as respondents who were divided into 2 groups, namely group 1 attended counseling which featured live demonstrations, while group 2 attended counseling where video was used as a medium. The instrument used was a questionnaire modified by researchers from Gorucu-Coskuner, H., Atik, E., & Taner, T. (2020) with 24 question items with yes and no answers. The validity test was carried out using the Pearson product-moment bivariate correlation technique where these results indicate that the value of "r count" (0.873)> "r table (0.227) means that the questionnaire is valid. Reliability test using alpha technique (Cronbach's) obtained r count (0.919)> "r alpha" (0.227) then the questionnaire was declared fit for use. Furthermore, bivariate analysis was carried out by comparing the knowledge of the two groups using the Mann-Whitney analysis.Results: A meaningful difference was found between the use of live demonstration and videos at P <α = 0.05 and p = 0,000. The mean score of the pretest done in group 2 was 96.70, while the one of the groups 1 was 48.30 which scores increased in the posttest to 105.39 and 39.61.Conclusion: Therefore, the use of video media has been found more effective than the use of live demonstrations in improving students’ first aid knowledge. Based on this finding, it is considered necessary to create more tutorial videos to improve first aid knowledge of the community especially students. Keywords: Counseling, Demonstration, Video, First Aid, Traffic Accident.
THE RELATIONSHIP BETWEEN FAMILY SUPPORT AND THE READINESS OF THE MENARCHE IN YOUNG WOMEN
Authors: Sari Etika Purnama
Published: November 2020

Background: Sexual maturity in young women is characterized by menarche. The changes occurring at the moment of the menarche cause teenagers to become awkward. Therefore, teenagers need to organize behavioural adjustments that require family support, especially parental support.Objectives: The purpose of this research is to analyse the family support relationship with the readiness of menarche in young women.Design: The design of this research is non-experimental with correlation methods and cross sectional approaches.Methods: The population of this study is all students of 5th and 6th grade Elementary School, Taman Belajar Surabaya who have not had a menstrual period of 40 students. Sampling techniques use simple random sampling. Large sample of 36 respondents. Collection of data using a family support questionnaire and a target readiness questionnaire.Results: A statistical test is conducted using SPSS, the FisherExact test, which shows that P = 0.001 < α = 0.05, where the hypothesis is accepted which means there is a significant link between family support and the readiness of the menarche in the young womenConclusion: There is a relationship between family support and readiness to target because of the provision of good family support so that the young women have a mental knowledge and strengthening to confront the menarche. It is hoped that the family will pay more attention to the children when they begin to step up, especially when the young women are ready to face the menarche. Keywords: Family support, menarche readiness, young women
THE EFFECT OF SUITABILITY OF PROVIDING COMPLEMENTARY FOODS ON THE INSIDENCE OF STUNTING AND ANEMIA IN TODDLERS
Authors: Rizki Lailatul Khusnul , Rahayu Esty Puji
Published: November 2020

Background: Stunting is a chronic nutritional problem in toddlers characterized by height that is not appropriate for their age. Children who are stunted will be at risk for disease and when growing up are at risk for degenerative diseases. The effect of stunting does not only affect health but also affects children's intelligence. Apart from stunting, anemia in children is also a health problem in developing countries (Ministry of Health, 2018).Objectives: The purpose of this study was to analyze the accuracy of giving complementary foods to the incidence of stunting and anemia in toddlers.Methods: The type of research used is analytical survey with a retrospective design. The population in this study are all toddlers at Porong Public Health Center who meet the inclusion criteria. The sample of this research is taken by cluster random sampling technique of 99 respondents. Data were collected using a questionnaire on complementary complementary feeding practices based on WHO (2003) regarding the principles of providing complementary foods. The reliability test of this questionnaire obtained a Cronbach’s Alpha value 0.723. Stunting Variables determined by calculating the Z-Score PB/U and Anemia variable was determined based on the measurement of the hb level Descriptive statistics and Chi-square Test with significance value less than 0.05 were used to analyzed data.Results: The results of this study are that there is an effect of the suitability of complementary feeding on the incidence of stunting and anemia, with a (ρ value  = 0.001) for the variable incidence of stunting and (ρ value = 0.021) for the variable incidence of anemia.Conclusion: Socialization on complementary complementary foods must be carried out frequently to avoid stunting and anemia so that the government's target to reduce stunting can be achieved. Keywords: Complementary Foods, Stunting, Anemia, Toddlers
VASCULAR ANOMALIES IN NEWBORNS: CLINICAL PRESENTATION, COMPLICATIONS, AND PECULIARITIES OF THERAPY
Authors: Benzar Iryna M. , Levytskyi Anatolii F. , Diehtiarova Daria S. , Fedoniuk Larysa Ya. , Stravskyy Yaroslav S. , Merkulova Daria A. , Sas Petro A.
Published: November 2020

The aim: To analyze cases of vascular anomalies in newborns retrospectively to study their main clinical signs and to determine indications for urgent treatment.
Materials and methods: A retrospective review of 281 pediatric vascular anomalies diagnosed between 2011 and 2019 was performed. The results of clinical examination, prenatal history, laboratory, sonography, and radiological data were evaluated.
Results: Clinical manifestations in the newborn period documented in 170 (60.5%) patients, anomalies were visualized prenatally in 8.9% cases. Five newborns with head and neck LMs required urgent treatment, which amounted 7.9% of all newborns with LMs. The indication for urgent surgery was acute respiratory failure. Partial malformation resection with tracheostomy was performed to those patients, along with intraoperative injection of sclerotherapeutic agents and argon coagulation of residual malformation tissues. EXIT procedure was performed in one case. No correlation (p=0.2) was found between the number of skin lesions and the severity of liver lesions in children with multifocal hepatic hemangiomas, congestive cardiac failure suddenly occurs in one patient in the third week of life. Two newborns with diffuse hepatic hamangioma were manifested right after the birth with clinical signs of liver failure, hypothyreosis, and cardiac failure. Short courses of corticosteroids performed in 7 patients with KHE and Kasabach-Merritte fenomemn for thrombocytopenia correction.
Conclusions: Clinical signs of vascular anomalies in neonatal period were seen in 57.5% children with vascular anomalies, and only 2.9% of them required treatment. Treatment itself is advantageous only in cases when life-threatening complications develop, such as airways obstruction, cardiac and/or liver failure, thrombocytopenia.
TOXICOLOGICAL AND MICROBIOLOGICAL ESTIMATION LEVEL OF POLLUTION ECOSYSTEMS IN THE INDUSTRIAL REGION OF UKRAINE – KRIVOY ROG CITY
Authors: Hryhorenko Luibov V. , Yehorova Svitlana Yu.
Published: November 2020

The aim: Scientific substantiation necessary of PMWW application for the ecologically safe formation of the secondary ecosystems in the mining and iron ore processing areas.
Materials and methods: Sanitary-chemical investigation of water samples (n=132); biological objects – plants and aquatic biota was conducted on the content of Pb, Cd, Zn, Mn, Cu, Cr, Ni, Fe (n=112); wild plants samples (n=135); sanitary-microbiological and parasitological indicators 1 – 3 years old waste water sludge (WWS) (n = 68).
Results: Overnormal concentrations of salt had been found in water samples, taken from the river Inhulets (2.1 MPL), sulfates and carbonates (2.7 MPL), iron (2.1 MPL), chloride (1.7 MPL), magnesium (3.1 MPL). In wells from nearest villages water is not suitable for drinking purposes and contains total sum of salts – 4.97 MPL, sulfates and carbonates – 5.16 MPL, cadmium – 3.7 MPL, lead – 1.53 MPL. Thus, the toxic heavy metals concentrations (Pb, Cd, Zn, Mn, Cu, Cr, Ni, Fe) in the fish and amphibians did not exceed the permissible levels.
Conclusions: Total pollution of the soil within six months after application of sludge correspond to the “permissible” level (Zc=1.61). Use of clearing facilities sludge aged from 1.5 years old and of longer in the amount 15 kg/m2 did not lead to increased concentration of heavy metals in the top layer of dumps.
COMPLEX TREATMENT THE PATIENTS WITH PSORIASIS AND CONCOMITANT ACTIVATED HERPES VIRUS INFECTION, TYPES 1, 2
Authors: Fedorova Ulyana V. , Syzon Orysya O. , Dashko Marianna O. , Voznyak Iryna Ya.
Published: November 2020

The aim: Is to increase effectiveness and assess safety of the antiviral therapy in complex treatment of patients with psoriasis with activated chronic herpes virus infection of types 1 and 2.
Matherials and methods: 120 patients and 25 practically healthy persons were examined.
Results: It has been studied an effect of antiviral therapy on the background of basic therapy in patients with P+HSV 1,2: the percentage of HSV 1,2 DNA detection after the use of acyclovir and/or inosine pranobex was decreased in saliva from 22.0±3.43 % to 6.7±1.32 % (р<0.01) and in epithelium – from 33.3±4.23 % to 6.7±1.8 % (р<0.01); The use of antiviral therapy has showed a decrease in the expression of miR 155 molecules from 126.3 ±10.5 U/6 to 62.4±5.48 U/6 (р<0.05), an increase in the number of T-regulatory lymphocytes from 6.8±1.25% to 9.1±1.41% (p=0.0503); a decrease of IFN-α level in saliva from10.1±1.84 ng/ml to 8.2±1.27 ng/ml (р1=0.0398); in the serum IL-23 level was significantly decreased from14.9±2.11 pg/ml to 8.8±2.03 pg/ml (р<0.05) and TGF-β synthesis was increased from 3.9±1.23 pg/ml to 9.3±2.21 pg/ml (р<0.01).
Conclusions: An improved method of treatment and evaluation of its clinical and immunological effectiveness based on an integral criterion was suggested as a result of conducted antiviral therapy amid basic therapy in patients with psoriasis with activated HSV-1 and HSV-2.
RESULTS OF ACUTE PURULENT CHOLANGITIS TREATMENT WITH GENETIC ENGINEERING ANALOGUE OF DORNAZE-ALPHA NATURAL ENZYME
Authors: Pokidko Mariya I. , Vovchuk Igor M. , Yarmak Oleh A.
Published: November 2020

The aim: To evaluate the effectiveness of the proposed method of surgical treatment of patients with acute purulent cholangitis.
Materials and methods: The research is based on the analysis of the treatment results in 104 patients with acute purulent cholangitis. The volume of surgical interventions on the biliary tract in patients was as follows: endoscopic papillosphincterotomy (EPST) + naso-biliary drainage; EPST + laparoscopic cholecystectomy; cholecystectomy + choledocholithotomy + drainage of the common bile duct.
Results: The APACHE-2 scale assessment for patients in the control group was 12,80 ± 1,73, with the SOFA scale - 4,32 ± 0,31 points. Accordingly, the assessment for patients in the main group with the APACHE-2 scale is 11.76 ± 0.81, with the SOFA scale - 4.33 ± 0.79 points. The results obtained in both the control and the main group indicate that the physiological reactions of the organism to the disease, treatment, development of organ dysfunction are reflected in the integrated severity assessment scales.
Conclusion: The performed analysis of clinical and laboratory results of treatment in both groups established the high efficiency of the proposed treatment method in patients with acute purulent cholangitis, which promotes the more rapid medical and social rehabilitation in this category of patients.
PARTIAL LAPAROSCOPIC ADRENALECTOMY - ANATOMICAL BASIS AND OPERATION TECHNIQUE
Authors: Styopushkin Sergiy P. , Chaikovskyi Viktor P. , Chernylovskyi Volodymyr A. , Sokolenkо Ruslan V.
Published: November 2020

The aim: To optimize the indications for partial laparoscopic adrenalectomy (PLA), to give a detailed outline of a PLA technique and to provide technical tips to ensure safe and highly-effectiveness, based on the knowledge of adrenal anatomy and blood supply.
Materials and methods: Between January 2010 and September 2018, our department performed 47 adrenal glands surgeries. The operations included 29 total laparoscopic adrenalectomies (TLA), 4 open adrenalectomies (OA) and 14 partial laparoscopic adrenalectomies (PLA).
Results: The histopathological examination of all operated patients detected 9 (19.1%) malignant tumors, including 5 metastatic tumors. Benign tumors includes 24 (63%) adenomas, 8 (21%) pheochromocytomas, 4 (10,5%) cysts and 2 (5,5%) ganglioneuromas. Post-PLA histopathological findings revealed 6 adenomas, 2 pheochromocytomas, 4 cysts and 2 ganglioneuromas.
Conclusions: Keeping in mind anatomical features of adrenal gland blood supply in highly-selected patients, PLA can be performed in a number of patients. 2 mm of a minimal resection margin is enough to preserve a false tumor recurrence. Anatomically grounded PLA is becoming a new standard of benign adrenal gland tumors treatment, providing an opportunity to save more adrenal gland functional tissue and to prevent hipocorticism development in postoperative period.
HYGIENIC SUBSTANTIATION OF NECESSITY FOR MONITORING IN THE ENVIRONMENTAL OBJECTS OF SDHI FUNGICIDES CONSIDERING THEIR POSSIBLE IMPACT ON THE THYROID GLAND
Authors: Antonenko Anna M. , Shpak Bohdan І. , Vavrinevych Оlena P. , Omelchuk Sergii T. , Zinchenko Tetiana I.
Published: November 2020

The aim: Was hygienic substantiation of necessity for monitoring in the environmental objects of SDHI fungicides considering their possible impact on the thyroid gland. Materials and methods: To test the proposed selection criteria for hygienic monitoring of pesticides that affect the thyroid gland, we evaluated 4 new SDHI fungicides from the chemical class of pyrazolecarboxamides (isopyrazam, pentiopyrad, sedaxan, fluxapyroxad). Results: Based on the results obtained, all studied compounds are assigned to the second pesticide group, hygienic monitoring of which is desirable but not required. This is due, on the one hand, to their low toxicity, to the other, to low environmental sustainability. Conclusions: It was shown, that compared to other classes of pesticides, the studied are much less dangerous in terms of groundwater contamination.
MEDICAL REHABILITATION SYSTEM AND ITS QUALITY CONTROL IN DEVELOPED COUNTRIES OF THE WORLD
Authors: Shevchuk Viktor I. , Yavorovenko Oksana B. , Belyaeva Natalia M. , Kurylenko Iryna V.
Published: November 2020

The aim: To review scientific literature dealing with evaluation of medical rehabilitation effectiveness and quality in the world. Materials and methods: Review and generalization of scientific literature on the criteria of evaluation of medical rehabilitation quality in advanced industrialized societies. Conclusions: Despite differences in the structure of medical rehabilitation in world societies, the end point is similar – assessment of quality of life of a sick person, measured by various criteria and standards. This experience is of great value for the development of national system of rehabilitation services.
Trait inheritance in bread spring wheat hybrids with synthetics with ABD genomic structure
Authors: Dokukina K.I. , Bohuslavskyi R.L.
Published: November 2020

There are prezented results of a study of early hybrid generations of bread spring wheat with synthetics (ABD genomic structure) combining the genomes of Triticum durum Desf. and Aegilops tauschii Coss. for inheritance of plants height, ear productivity elements: length, spikelet and grain number, grain weight; 1000 grain weight. In all five combinations, transgressive forms were found out on different traits with a frequency of 6% to 8% and a transgression degree of 6 to 17%. In the hybrid Kharkivska 26 / AD 68.112 / Ward // Ae.squarrosa (369), such plants are distinguished on five traits: plant height and parameters of the main ear – length, spikelet and grain number, grain weight. The presence of transgressions indicates an increase in the manifestation level of these traits in bread wheat.
Sources of resistance to fusarium wilt among different Callistephus chinensis (L.) Nees varieties
Authors: Trokhymchuk A.I. , Shevel A.I.,
Published: November 2020

Aim. To clarify the biological characteristics of some Chinese calistephus cultivars, to identify sources of resistance to Fusarium wilt in the Kyivska oblast.
Results and Discussion. The Chinese calistephus gene pool collection of the Institute of Horticulture NAAS (IH), which includes 104 accessions belonging to 33 varieties, was the test material. Evaluation of the collection gene pool showed that 65 Chinese calistephus accessions were almost not affected by Fusarium. Thirty-one cultivars were weakly affected by this pathogen; five cultivars were severely affected; three cultivars - very strongly. Most of the resistant industrial cultivars are intended as cut plants (bouquets). The infestation level in the collection Chinese calistefus cultivars, differing in decorativeness, was assessed. It was found that 65 collection cultivars (62.5%) were very highly resistant. In 47 cultivars (37.5%) of the entire collection, Fusarium-induced damage varied 3 to 30%. However, there are high-quality cultivars (in terms of their ornamental characteristics) where 7-53% plants die because of Fusarium annually. Highly resistant to Fusarium cultivars are also referred to the folowing varieties: Printsessa, Khudozhestvennaya, Troiandopodibna, and others. Analyzing the Calistefus seed productivity, we can see that the average seed productivity per plant (g/bush) of Fusarium-susceptible cultivars is always lower than that of resistant cultivars belonging to the same variety.
Conclusion. It was found that 65 accessions (62.5% of the total number of the collection accessions) were sources of resistance to Fusarium wilt. These include IH-bred cultivars: Mashenka, Letnyaya Noch, Tsarevna, Sofiya, Yantarnaya, Krasunia, Shokoladka, Flamingo, Mriya, and others. Forty-seven highly decorative cultivars (95-99 points), i.e. 45.2% of the entire collection, showed 3 - 30% Fusarium-induced damage. It was revealed that the average seed productivity per plant (g/bush) of Fusarium-susceptible cultivars was always lower than that of cultivars which are resistant to this pathogen. It was proven that the longer the anthesis, the more frequently plants got affected by Fusarium.
Вплив системи догляду за кроною на декоративність і довговічність рослин сортів Syringa vulgaris L.
Authors: Горб В. К. , Клименко Ю. О. , Довгалюк Н. І.
Published: November 2020

Досліджено вплив способів обрізування крони рослин Syringa vulgaris L. на їхню декоративність і довговічність. Встановлено, що досягти найкращого результату можна тільки за регулярного догляду за кроною. Спонукає до цього, щонайперше, дихотомічне (несправжнє) гілкування, за яким кожна однорічна гілка продукує навесні два пагони з верхівкової пари бруньок та ще кілька – з бруньок, що розташовані нижче по осі цієї гілки. Отже, щороку загальна їхня кількість щонайменше потроюється. Коренева система не зможе за цей час збільшити в таких обсягах свою масу і фізіологічну активність, що корелятивно спричиняє значне зменшення розмірів пагонів і суцвіть. Якщо догляд був нерегулярний або відсутній, виникає потреба інтенсивного прорідження або кардинального омолодження крони. Доведено, що цими заходами можна поліпшити декоративність рослин, але на довговічність вони вплинуть негативно. Зумовлює це дві причини. Перша – запобігання ран внаслідок видалення гілок на кільце. Встановлено, що навіть 1,5-2,0-сантиметрові зрізи на стовбурі чи скелетних гілках ніколи не загояться, а за 10-15 років їхня деревина струхліє, утворивши порожнину. Деревина великих ран руйнується швидше, що призводить до виникнення дупел та повільного відмирання всієї рослини. Другою причиною вкорочення довговічності є раптово порушений функціональний корелятивний коренево-листковий зв'язок, що є наслідком різкого зменшення в омолодженій рослині надземної частини. Спочатку це призведе до сповільнення фотосинтезу (крона майже відсутня), а потім, корелятивно, й до затухання кореневого синтезу: через мізерне надходження асимілятів до коренів. Унаслідок цього загальна маса фізіологічно активної частини кореневої системи теж значно зменшиться, що негативно вплине на довговічність рослини загалом. Декоративність кущів через це з року в рік погіршується. Також встановлено, що до обрізування крони змушує й загущена посадка бузків. Для відновлення її декоративності спочатку варто видалити кволі рослини, а в решти – знизити крону приблизно на третину аби наблизити її до кореневої системи, що забезпечить рослинам фізичну витривалість та дещо внормує в них функціональний коренево-листковий зв'язок. Здійснити цей захід треба якомога раніше в часовому вимірі, бо, окрім згаданого, рослини почнуть страждати й від хвороб. Потужні гілки потрібно вкорочувати, а не вирізати на кільце, аби не нанести стовбурам і гілкам першого порядку великих ран. За такого підходу до обрізування крони бузки будуть декоративними й здебільшого випадків – довговічними.
Радіальний приріст соснових насаджень, створених з різною густотою в Житомирському Поліссі
Authors: Краснов В. П. , Жуковський О. В. , Зборовська О. В. , Мельник В. В.
Published: November 2020

Досліджено насадження сосни звичайної (Pinus sylvestris L.) в Житомирському Поліссі на стаціонарному досліді № 1 впродовж 2010-2012 років. Проаналізовано величини середнього, максимального та мінімального радіальних приростів сосни звичайної, а також динаміку поточного радіального приросту. Виявлено, що середня величина радіального приросту в насадженнях коливається в діапазоні 2,49-3,70 мм. На варіантах досліду в нaсaджeнняx з початковою густотою 4000, 2000 і 1000 шт.·га-1 відмінність середнього радіального приросту відсутня або знаходиться в діапазоні 1-8 %. Величини максимальних приростів у соснових насадженнях досліду коливаються в діапазоні 5,34-7,32 мм, а величини мінімальних – 0,83-1,36 мм. Продемонстровано динаміку радіальних поточних приростів й різницю між ними. Встановлено, що достовірна різниця коливається в діапазоні 3-34 %. Вона спостерігається мiж нaсaджeннями з початковою гycтoтoю 4000 i 2000 шт.·га-1 у період з 1982-1984 до 1994-1997 рр., між сосняками з початковою кількістю дерев на одиниці площі 2000 і 1000 шт.·га-1 у період з 1982-1985 до 1999-2001 рр., і між насадженнями з початковою густотою 4000 і 1000 шт.·га-1 у період з 1982-1984 до 2006-2010 рр. Зроблено висновки про те, що величина середнього радіального приросту і формування поточного радіального приросту залежать від початкової густоти, а величини максимального та мінімального поточного радіального приростів не залежать від початкової густоти насадження.
Аналіз лісотаксаційної структури дубових лісостанів Західного Лісостепу
Authors: Новак А. А. , Копій С. Л. , Фізик І. В.
Published: November 2020

Проаналізовано особливості поширення дубових деревостанів у Західному Лісостепу України. Здійснено аналіз лісотипологічної структури деревостанів за участю дуба звичайного (Quercus robur L.) в умовах Західноукраїнського лісостепового лісогосподарського округу. Досліджено структуру площ дубових лісостанів у розрізі едатопів та типів лісу, вивчено їх бонітетну та повнотну структуру, склад та походження. Встановлено, що найбільша частка дубових лісостанів Західного Лісостепу зосереджена у грудових умовах – 79,3 %. Сугрудові типи лісорослинних умов становлять 20,5 % від площі дубових лісостанів. За ступенем зволоження ґрунтів, дуб звичайний, на теренах Західноукраїнського лісостепового лісогосподарського округу, віддає перевагу свіжим умовам, де зосереджено 65,6 % дубових лісостанів регіону. Встановлено, що у досліджуваному регіоні дуб звичайний бере участь у формуванні 47 типів лісу, з них у 19 виступає як типотвірна порода. Більшість дубових деревостанів має І клас бонітету (49,9 %) і значна частина (35,7 %) насаджень – ІІ. Середній бонітет становить І,3. Дубові деревостани у Західному Лісостепу, в основній масі, є середньоповнотними. Їх середня повнота становить 0,73. Найбільша частка (39,3 %) приурочена до повноти 0,7. Частка середньоповнотних деревостанів загалом становить 55,9 % від площі дубових лісів досліджуваного регіону. Питома вага високоповнотних насаджень у повнотній структурі дубових лісостанів Західноукраїнського лісостепового лісогосподарського округу становить 42,3 %. Виявлено, що у дубових лісостанах Західного Лісостепу за складом переважають насадження, де дуба у складі тільки 4 одиниці – 20 % від загальної площі. Середній коефіцієнт участі дуба у складі насаджень – 5,7. Вікова структура дубових лісів Західного Лісостепу є нерівномірною, із значною перевагою середньовікових деревостанів – 54,2 %. Стиглі деревостани займають тільки 8,0 % площі дубових лісів Західного Лісостепу. Середній вік дубових лісостанів Західноукраїнського лісостепового лісогосподарського округу – 61,2 років. З'ясовано, що у досліджуваному регіоні переважають (69,5 %) штучні насадження, створені, зазвичай, садінням лісових культур. Природні насінні дубові деревостани становлять 27,3 % від площі дубових лісів Західного Лісостепу, деревостани вегетативного природного походження – 3,2 %.
The institutional thickness of an inner periphery in the cross-border region between Central Bohemia and Eastern Bohemia
Authors: Komárek Marek , Chromý Pavel
Published: November 2020

The paper aims to analyze the “soft” factors of local development and to understand the nature of the socio-economic differences between municipalities in an inner periphery in Bohemia. The partial goals are to explain which internal conditions are conductive to the formation of these ties of cooperation, to reveal which power structures are involved in the ties of cooperation, and to assess the direction of these interactions. The conclusions are formulated and discussed in relation to the concept of institutional thickness. Our research confirmed the key differentiating role of mayors in local interactions and the importance of administrative boundaries – especially boundaries of self-government regions. These boundaries had the effect of constraining the formation of formal and informal relations between actors in territorial development. The research also provides evidence of the continued existence of links between municipalities that were formed during the communist period. The data come from the author’s field survey among the mayors.
From Chernozem to Luvisol or from Luvisol to Chernozem? A discussion about the relationships and limits of the two types of soils. A case study of the soil catena of Hrušov, Czechia
Authors: Strouhalová Barbora , Gebhardt Anne , Ertlen Damien , Šefrna Luděk , Flašarová Kristýna , Kolařík Petr , Schwartz Dominique
Published: November 2020

The patchy character of the distribution of Chernozems and Luvisols formed on loess is often observable on the pedological maps, on a large scale, in Czechia. The focus of the paper is to examine the features of the soil catena of Hrušov (Czechia), which is characterized by the simultaneous presence of Chernozem, Luvisol and Luvic Chernozem – without obvious environmental reasons. A catena of only 330 meters is considered a system of transformation between these soils. Along with field work and the pedological analysis, we used the soil micromorphology method to understand the processes of pedogenesis. We concluded that the presence of considerably different soil types on a small scale is due to intensive agriculture. We found that the present Chernozem is formed on the Luvisol by retrograde soil evolution, which included a shift in the vegetation, erosion, and recarbonation. The evolution of Luvisol in the lower part of the catena has been considerably modified.
Educación Holística: Una Oportunidad para Transformar la Realidad Educativa en el Siglo XXI
Authors: Quevedo Lezama Christian Rafael
Published: November 2020

Este ensayo se propone realizar un análisis teórico a la educación holística, sus postulados referidos a integrar el aspecto emocional y espiritual, y la construcción de conocimientos. En respaldo a este marco, se presentan algunas iniciativas propuestas por algunos autores en la incorporación de la visión holística experimentados en la educación. Producto de esta investigación, se estima identificar a la educación holística como un modelo de enseñanza transformadora que estimula en los educandos una mayor conciencia individual, haciéndoles partícipes dentro de sus comunidades, ello como resultado de un enfoque al aspecto emocional y cognoscitivo en los estudiantes.
RADIOTHERAPY FOR THE TREATMENT OF LOCALLY ADVANCED NON SMALL CELL LUNG CANCER
Authors: Arsenev Andrey , Kanaev Sergey , Novikov Sergey , Barchuk Anton , Antipov F. , Tarkov S. , Nefedov Andrey
Published: November 2020

In this literature review we analyze the effectiveness of radiotherapy (as an independent method and in combination with surgery and chemotherapy) in the treatment of locally advanced non-small cell lung cancer. The postoperative adjuvant radiotherapy can increase overall survival and reduce the frequency of local recurrences in IIIA / N2 stage of NSCLC, however, its positive effect can be offset by the damage to surrounding structures. Modern high-tech equipment, improved planning systems, methods radiation doses delivery, and the fractionation regimen can improve the outcomes of radiation therapy. No bimodal treatment has shown advantages over other combinations. Some improvement in survival was noted in a number of studies using three-modal treatment, but it was also associated with an increase in the proportion of postoperative complications, especially after pneumonectomies. The heterogeneity of the IIIA / N2 NSCLC group and criteria for their operability present certain difficulties for a correct comparison of the treatment results, which requires further discussion. In most studies, insufficient attention has been paid to the influence of multimodal treatment on the quality of life of patients, which, taking into account comparable results of treatment, can be crucial in determining indications and contraindications.
METHODS FOR CREATING A MODEL OF UVEAL MELANOMA
Authors: Kit Oleg , Goncharova Anna , Tkachev Sergey , Protasova Tatyana
Published: November 2020

Uveal melanoma is a big challenge for medicine, because despite successful local treatment, metastatic disease develops frequently and this is an important factor affecting patient survival. Revealing mechanisms of pathogenesis of this disease and developing targeted therapy requires high-quality animal models that reproduce many aspects of tumor biology, mimic its metastasis dissemination and, most importantly, can be the basis for understanding the principles of diagnosis and treatment. Methods for creating a model of uveal melanoma include injecting syngeneic skin melanoma cells to the experimental animals, injecting xenogenic uveal and skin melanoma cells that can be of both human and animal origin, as well as transplanting xenografts obtained from patients and creating transgenic and induced tumor models. In this review, we analyzed the data of the last 30 years on the methods of modeling uveal melanoma, described the advantages, disadvantages and features that must be considered.
BIOLOGICAL DOSE UNIFORMITY IN SPREAD-OUT BRAGG PEAK OF PROTON SCANNING BEAM THERAPEUTIC FACILITY
Authors: Beketov Yevgeniy , Isaeva Yelena , Solovev Aleksey , Golovanova Olga , Ulyanenko Liliya , Malakhov Yegor , Kisel Anastas , Ulyanenko Stepan , Shegay Petr , Ivanov Sergey , Kaprin Andrey
Published: November 2020

Introduction. Biological dose uniformity in SOBP of the modem proton therapy facilities is an important issue. The results of a number of studies reveal an increased biological efficiency at the distal area of SOBP.
The aim of the study was to verify this effect for Prometeus facility, which provides proton therapy with a scanning pencil beam.
Material and methods. The study was conducted at A. Tsyb MRRC. Melanoma B16F10 cells were used for the experiments. The biological efficacy of protons was evaluated by clonogenic assay (cell survival) and comet assay (DNA damage). Proton dose range within the experiments was 4-8 Gy. Cells were irradiated both in monolayer and suspension conditions. Proton biological efficacy along SOBP was evaluated in the proximal, middle and distal positions. All irradiations were carried out with one field.
Results of in vitro experiments indicate that Prometeus facility treatment planning system in case of single-field irradiation provides the uniformity of the biological dose in SOBP. According to cell survival, there is a tendency for a slightly greater efficiency of protons in the proximal part of SOBP. Data on DNA damage confirm this conclusion.
Conclusion. Therefore, unlike a number of modern installations for proton therapy in the case of the facility used in the study, there is no increase of biological dose in the distal area of SOBP.
PHYSICAL METHODS OF REHABILITATION IN PATIENTS WITH LUNG CANCER: A SCIENTOMETRIC ANALYSIS OF EVIDENCE-BASED RESEARCH
Authors: Kasparov Boris , Semiglazova Tatyana , Kovlen Denis , Ponomarenko Gennadiy , Klyuge V. , Krutov Anton , Zernova M. , Kondrateva Kristina , Khidishyan K. , Adkhamov Bakhtiyar , Semiglazov Vladislav , Levchenko Yelena , Belyaev A.
Published: November 2020

Relevance: The strategy of finding evidence on the use of rehabilitation technologies in patients with lung cancer is based on scientometric analysis.
Methods: For the period from 1991 to 2018. Using PICO (T) technology in electronic databases (PEDro, PubMed, Elibrary, Cochrane Library), full-text analysis of 249682 studies was performed. MeSH bibliographic descriptors: «lung cancer», «rehabilitation», «physical therapy». Studies were evaluated on a PEDro scale, which includes 10 parameters of the level of evidence: randomization, endpoint evaluation, blinding, etc.
Results: The verified distribution profile of research on the quality of evidence showed that 55.9% of studies had a quality level of 4 to 8 on the PEDro scale. One study had a quality level of 9 points (0.8%). The bulk of research (69%) is devoted to the study of the effectiveness of exercise. Evaluation of the effectiveness of respiratory gymnastics, traditional health practices (Tai Chi, gypsy, yoga, etc.) are devoted to 7.5% of the studies. 6.5% of works are devoted to studying the effectiveness of acupuncture. Analysis of the effectiveness of non-invasive ventilation technology (mainly CPAP), the effects of artificially modified air (aerosol therapy, aerophytotherapy), and therapeutic physical factors of mechanical nature (massage, vibrotherapy) is devoted to 10.8% of studies. The use of technologies of physical rehabilitation measures using electromagnetic factors is devoted to 3.2%. In 2% of the studies, an assessment of the effectiveness of respiratory gymnastics was presented, and in a number of works, such technologies of physical rehabilitation, which are gaining popularity in the rehabilitation of patients with lung cancer, have been studied as kinesio-taping and audio-visual relaxation (1% each).
Conclusion: Clinical recommendations developed on the basis of the obtained results will form the basis of a new, evidence-based stage in the development of the rehabilitation of patients with lung cancer in Russia.
ISOLATED PULMONARY METASTASES: EVOLUTION OF THE TREATMENT TECHNOLOGIES
Authors: Mikhnin Aleksandr , Van T. , Dubinina Tatyana , Mamontov Oleg , Levchenko Yelena , Levchenko V.
Published: November 2020

The lung is the most commonly attacked organ in metastatic disease. In many patients who were successfully cured of primary cancer, pulmonary metastases for a long time may be the only, and sometimes the final manifestation of the disease. This kind of dissemination is known as isolated lung metastases. The prognosis for untreated patients with pulmonary metastases is unfavorable: 5-year survival does not exceed 5%. This survey considers the evolution of technologies for the treatment of isolated metastatic lung lesions from surgical metastasectomy to combined methods of high-dose regional chemotherapy.