bluuebunny/crossref_metadata_2025 huggingface dataset:
Perancangan Instrumen Evaluasi Pembelajaran Berbasis Website di Sekolah Dasar Negeri 55 Air Pacah Kota Padang
Authors: Hendriani Maifit , Gusteti Meria Ultra
Published: November 2023

The results of observations and interviews conducted at State Elementary School of 55 Air Pacah, during online learning during the covid 19 pandemic there are 2 methods used in learning evaluation. They are (1) using conventional paper-based media that students take home and (2) sending photos of assignments or photos of questions through the WhatsApp application to parents. The use of this method makes it difficult for educators to process values. The use of website-based media in the evaluation of learning is the right solution in the current era. With a website-based evaluation instrument, correction of calculations can be made directly and students immediately get feedback. The training methods are in the form of presentations, demonstrations, hands-on practice with assistance in making evaluation instruments, and assignment methods. As a result of this service activity, educators can understand how to make website-based learning evaluation instruments and be skilled at using them. In addition, since the training was held until now, educators have applied it in online learning.
Program Penerapan Omah Sinau dan Pengaplikasian WiFi dalam Meningkatkan Minat Belajar Siswa di Masa Pandemi
Authors: Alviana Vina , Muasomah Muasomah
Published: November 2023

Omah Sinau is the application of Out of School Education concept where education is designed to teach learning citizens to have skills and or knowledge and experience carried out outside of formal education (schooling). This lesson is addressed to residents of Blarakan Tenggah Kebulen Village, especially RT 003 RW 015 Sapuro Kebulen. Some of the activities carried out were house-to-house socialization in dealing with the ineffectiveness of online learning and educating learning participants with different methods which were carried out in Blarakan Kebulen Village. Considering the low importance of overcoming children's learning boredom, this service aims to help the residents of Sapuro Kebulen in online learning during the COVID-19 pandemic era. The study uses observational research and case studies in following up on observations and interviews with the surrounding community to form Omah Sinau program activities to increase student interest in learning during the current pandemic. As a result, through the activities above, they are able to make the public aware of the ineffectiveness of online learning during this pandemic and can provide knowledge to students regarding the difficulties of overcoming online learning.
PRETEND PLAY BASED IMAGE GUESS AS A SOLUTION TO INCREASE REMEMBER OF EARLY CHILDHOOD
Authors: Yuliyanto Aan , Rustina Iis Listiani , Rosiyana Rosiyana
Published: November 2023

At the age of 0-6 years, the child is unable to remember for a long time. This is due to the many activities they do that cause fatigue so quickly and make them forget any previously obtained information. This indicates that the child has a weak memory. However, if the child receives information through meaningful experiences the child will easily remember what he did. Therefore, AUD learning must be integrated with games to make learning fun. This study aims to determine the relationship between-based image guessing games Pretend Play to improve children's memory and to find out the advantages of Pretend Play on memory. Based on a study conducted based image guessing games pretend play can be used as an alternative to improve early childhood memory.Pada usia 0-6 tahun anak tidak mampu mengingat dalam jangka waktu lama. Hal tersebut diakibatkan karena banyak aktivitas yang mereka lakukan sehingga menimbulkan lelah begitu cepat dan membuat mereka melupakan suatu informasi yang didapatkan sebelumnya. Hal ini menandakan anak memiliki daya ingat yang lemah. Namun apabila anak menerima informasi melalui pengalaman bermakna anak akan mudah mengingat kembali apa yang dilakukannya. Oleh karena itu, pembelajaran AUD harus diintegrasikan dengan permainan agar belajar menjadi menyenangkan. Kajian ini bertujuan untuk mengetahui hubungan permainan tebak gambar berbasis Pretend Play terhadap peningkatan daya ingat anak dan mengetahui kelebihan Pretend Play terhadap daya ingat. Berdasarkan kajian yang dilakukan permainan tebak gambar berbasis Pretend Play dapat dijadikan alternatif untuk meningkatkan daya ingat anak usia dini.
Implementation of Discovery Learning Model on the Learning Motivation of Sixth Grade Students
Authors: Kurniawati Ani
Published: November 2023

The research objective was to determine the effect of the discovery learning model on the student learning motivation. This study employed the classroom action research method. The research population were MI PUI Cigadog students, involving sixth-grade students (30 students) as samples. The sampling technique used was the total sampling. The instruments utilized were observations and questionnaires. The results of the first cycle of learning showed an achievement of 65.04%, as derived from data tabulation, falling into the category of satisfactory. Meanwhile, in the second cycle, through the evaluation and the successful refinement of the implementation of the discovery learning model, a significant improvement was observed. The percentage of learning motivation questionnaire results in the second cycle was 73.47%. The learning motivation outcomes fell into the "good" category, within the range of 70% to 79%. In conclusion, there was an evident enhancement in student learning outcomes in Physical Education from cycle to cycle, where both Cycle I and Cycle II showed an improvement. The discovery learning model can be employed by teachers as an alternative method to elevate the student motivation in learning Physical Education.
Life Skill Development Through Pencak Silat Activities in The Positive Youth Development Framework
Authors: Risyanto Aris
Published: November 2023

The purpose of this study was to examine life skill development through pencak silat activities in the positive youth development context. This study used experimental research method. The study population consisted of students participating in pencak silat courses at Subang University. The sampling technique used in this study was the purposive sampling technique, involving 20 students. In this study, the model used was the True Experimental Design. The research instrument used in this research was a life skills questionnaire with a Likert scale measurement. The analysis of this research employed IBM SPSS software version 25.0. Hypothesis testing used paired sample testing. The results of the analysis gained the value of sig (0.00) (0.05) for the experimental group and the value of sig (0.066) (0.05) for the control group. This study concludes that the integration of life skills in the experimental group had an impact on the development of life skills. In future research, we will further discuss life skill development so that we can see the most important life skill component for life skill development.
Effectiveness of Modified Learning Media on Student Creativity
Authors: Akin Yogi , Suherman Ayi , Safari Indra , Susilawati Dewi , Sudrazat Adang , Nugraha Reshandi , Brilian Mohamad
Published: November 2023

This study aimed to determine the influence of modified learning media on the student creativity. The research method employed an experimental method with a pretest-posttest control group design. The sample of this study consisted of PETE for Elementary School students selected through purposive sampling. The research instrument utilized a creativity questionnaire. Based on the data analysis, the significance value was 0.019, indicating a significant influence of modified learning media on the student creativity. This study concludes that there was a significant impact of modified learning media on the student creativity. Modifying learning media can be considered a viable alternative in education to enhance creativity and other cognitive components.
Public Employment Services and Vulnerable Youth in the EU: The Case of Rural NEETs
Authors: Simões Francisco , Marta Elena
Published: November 2023

The Covid-19 pandemic created unprecedented pressure to accelerate public employment services (PES) digitalisation across Europe. In fact, there is now a considerable amount of funding dedicated to that goal in broadband policy packages, such as the Recovery and Resilience Mechanism. This pressure for digitalizing PES presumes that its benefits outweigh the existing risks, regardless of citizens’ singularities, such as vulnerable young people going through the school-to-work transition. Bearing that in mind, and following a bioecological model framework, our article addresses two main goals. Firstly, based on a targeted literature review, we detail the challenges and possibilities posed by PES digitalisation for vulnerable young people in EU countries, which have been widely overlooked in the literature. We specifically argue that despite several practical advantages (e.g., releasing staff from time-consuming administrative tasks), PES digitalisation will only be beneficial for vulnerable young people if three interrelated challenges are taken into account: nurturing trust in institutions and digital tools, supporting digital transformation of PES institutional organization, and adopting a co-design lens for PES digitalisation. Secondly, using a knowledge integration approach, we describe a model for assessing PES capacity to digitally support rural young people not in employment, education, or training to enter the labour market. We conclude that the overemphasis on the expected advances of overall PES digitalisation must be followed by thoughtful consideration of PES digitalisation processes to ensure EU social inclusion targets for the younger generations.
The Recovery and Resilience Dialogues: Cheap Talk or Effective Oversight?
Authors: Bressanelli Edoardo , Chelotti Nicola , Nebbiai Matteo
Published: November 2023

The recovery and resilience dialogues were introduced by the regulation of the Recovery and Resilience Facility, and the first of such dialogues took place in May 2021. The European Parliament invites the Commission, approximately every two months, to exchange views on matters relating to the national recovery and resilience plans and progress in their implementation. Through an analysis of an original dataset composed of the questions asked by the MEPs in the 10 dialogues held between May 2021 and April 2023, this article provides a systematic empirical assessment of the European Parliament’s capacity to hold the Commission accountable. Drawing on the literature on the economic and monetary dialogues and adapting the operationalisation of key variables to the new instrument, this article shows that the recovery and resilience dialogues are an effective instrument for information exchange and debate, but they serve as a weak instrument of political accountability. Additionally, it casts new light on significant differences between MEPs: South and East European members are considerably more active than members from Northern Europe. At the same time, parliamentarians only occasionally ask questions targeting other member states.
Contamination of Fruits, Soil Water Due to The Use of Agrochemicals in (Passiflora Ligularis), Oxapampa-Peru
Authors: Quispe Benito Filemón Buendía , Cabello Guillermo Gomer Cotrina , Rubén Bernal Marcelo Alfredo , Huaman María Soledad Aliaga , Villanueva Carlos Jesús Yupanqui , Manuel López Robles Zenón , Ulises Peña Carmelo , Luis De La Cruz Saravia Jorge
Published: November 2023

The conventional agriculture allowed the farmers being dependent to the mass and frequent use of pesticides, originating contamination of fruits, ground, water of escorrentía. Objective was To Determine the concentration of metals weighed in Passiflora's fruits ligularis produced at grounds and escorrentía's water with remains of metals weighed by intensive agroquímicos's use at Oxapampa's district. Himself I utilize the Experimental Comparative Design No. Determined him Arsénico's concentration, Mercury, Plomo, Cadmio, Cobre in signs collected of fields of production of three (ABC) previous groups you poll farmers. Results: You met the. Arsenic 0.004mg/Kg (Ch1Af), mercury 0,002 mg/Kg (Ab1Af, Ab2Af), lead 0,005 mg/Kg ( Ab1Af ), cadmium 0,004 mg/Kg ( Ab1Af, Ch1Af, PaCf ), copper 0,5 mg/Kg ( Ch2Af ). Ground Arsénico Ch1As, ARP3Cs 0,08 mg/Kg, mercury Ch1As, ARP3Cs, SA2Cs, PaCs 0,08 mg/Kg; I seal with lead Ch1As, ARP2Cs, Ch2As, AcAs, PaCs 0,08 mg/Kg, cadmium Acuzazú AcAs, 0,3 mg/Kg, copper Ab2Bs, Ch1As 30 mg/Kg. Water down of escorrentia; Arsenic SA2Ca 0.005mg/Kg, mercury Ch2Aa 0,008 mg/Kg, lead CaBa, QllAa, Ch3Ba 0,005 mg/Kg, cadmium Ab2Ba, AcAa, SA1Ba 0,004 mg/Kg, copper SA1Ba 1,5 mg/Kg. Conclusion: You had loud moral values of concentration of metals weighed at ground, water, fruits passing the maximum permissible limit.
Prevalência de sarcopenia em idosos e sua associação com a ingestão de nutrientes dietéticos
Authors: Bezerra Raíra Kirlly Cavalcante , Oliveira Lucidio Clebeson de , Silva Jânia Maria Augusta da , Lemos Priscilla Ferreira , Carvalho Francisca Patrícia Barreto de
Published: November 2023

Este estudo teve o objetivo de verificar a prevalência de sarcopenia em idosos e sua associação com a ingestão de nutrientes dietéticos. Estudo quantitativo, transversal e analítico desenvolvido com 114 idosos adscritos em uma Unidade Básica de Saúde localizada em Mossoró/RN. A coleta foi realizada por meio de um questionário sociodemográfico, inquérito dietético, avaliação nutricional e antropométrica. Para determinação da sarcopenia, utilizou-se testes como o Timed up and go, de preensão manual e equação preditiva de massa muscular esquelética. Identificou-se prevalência de sarcopenia de 26,32%, concomitante à presença de depleção de massa muscular, baixo peso, fator de risco aumentado com o avançar da idade e desempenho físico inadequado. Constatou-se que a chance dos idosos com idade até 70 anos apresentar sarcopenia diminuiu em 73%, contraposto aos com idade acima de 70 anos e que as chances dos usuários com Timed up and go adequado apresentarem a doença diminui em 75% comparada aos participantes que apresentaram inadequação no desempenho físico. Verificou-se que os idosos sarcopênicos consumiam quantidades reduzidas de muitos micronutrientes, como: vitamina D, E, C, B2, B3, B12, magnésio, selênio e zinco, além de apresentarem dieta inadequada em energia e proteínas, comparados aos não sarcopênicos. Ressalta-se a necessidade da expansão de conhecimentos sobre alimentação, prevenção e tratamento da sarcopenia.
Violência sexual: conhecimentos, atitudes e práticas de profissionais da Atenção Primária
Authors: Diógenes Isabelle Cantídio Fernades , Nascimento Ellany Gurgel Cosme do , Giovannini Patricia Estela , Felisberto Laíse Carla da Costa , Silva Júnior José Antonio da , Fernandes Thales Allyrio Araújo de Medeiros
Published: November 2023

Investigar conhecimentos, atitudes e práticas de profissionais da Atenção Primária à Saúde no atendimento

à mulher em situação de violência sexual. Estudo transversal, com 359 profissionais da Atenção Primária à

Saúde. Os dados foram analisados mediante estatísticas descritivas e teste razão de risco (p ≤ 0,05). Dos

71,8% apresentaram conhecimentos, atitudes (72,7%) e práticas preventivas (92,2%), avaliativas (85,5%),

de acompanhamento (72,1%) e assistenciais (46,8%) inadequadas. Profissionais com conhecimentos

inadequados tiveram risco aumentado para atitudes, práticas assistenciais e de acompanhamento

inadequadas. Entre profissionais com práticas preventivas, assistenciais e de acompanhamento

inadequadas, foi percebido risco maior para atitudes inadequadas. A maioria declarou não ter atendido

casos de violência sexual. Evidenciaram-se fragilidades relacionadas ao atendimento da mulher em

situação de violência sexual, indicando a necessidade de apropriada capacitação profissional, com ênfase

na superação da invisibilidade do problema.
Relação do ato de comer com o controle da doença e a qualidade de vida no Diabetes mellitus tipo 1
Authors: Santos Ana Lucia Lopes dos , Souza Marcio Leandro Ribeiro de
Published: November 2023

O objetivo deste estudo foi analisar a relação do ato de comer com o controle da doença e a qualidade

de vida em adultos com diabetes tipo 1 (DM1). Trata-se de estudo transversal, realizado através de um

questionário on-line com a versão brasileira do Diabetes Quality of Life Measure (DQOL-Brasil) e de

perguntas sobre controle alimentar. Foram incluídos 103 voluntários (85,4% mulheres). Nas relações

com a comida, 68,9% disseram sentir vontade de comer quando estão ansiosos, preocupados ou

tensos. O escore global foi de 2,36 ± 0,75 no DQOL-Brasil, e os domínios “satisfação” e “preocupações

relacionadas ao diabetes” apresentaram valores mais altos. A variável idade teve correlação negativa com

o escore global do DQOL-Brasil e com os domínios “impacto”, “preocupações sociais/vocacionais” e

“preocupações com diabetes”. Esta pesquisa demonstrou associação entre o ato de comer com o controle

do DM1, o que pode prejudicar a qualidade de vida desses indivíduos.
Covid-19 em Viçosa (MG): análise quantitativa, vacinal, etária e de gênero das pessoas infectadas e os impactos da vacinação
Authors: Oliveira Luís Guilherme Fonseca , Vieira Camila de Souza , Silva Anderson Antônio , Marques-da-Silva Eduardo  de Almeida , Tavares Mara Garcia
Published: November 2023

Este estudo teve como objetivo analisar o número de casos e óbitos por Covid-19 em relação a gênero e

idade, quantidade total de vacinas aplicadas e relação entre a aplicação das vacinas e número de mortes,

de janeiro a novembro de 2021, na cidade e região de Viçosa, Minas Gerais. Os dados foram fornecidos

pelo Setor de Vigilância Epidemiológica do município e pelos boletins diários da prefeitura. Em média,

houve mais de mil casos de infectados/mês de janeiro a julho, a maior parte adultos do gênero feminino.

A mortalidade também foi maior entre as mulheres. Foi registrada queda do número de casos e de mortes

coincidente com a aplicação da primeira dose de vacina em pessoas sem comorbidades e com início

de aplicação da segunda dose nos grupos prioritários. Tal achado indica a importância da imunização

coletiva no controle da pandemia
Tempo de exposição a telas em lactentes: comparação pré e durante a pandemia da COVID-19
Authors: Silva Francieli Aparecida Meurer da , Erhardt Amanda dos Santos , Carneiro Mayara Martins Cesário , Martins Tais Beppler , Montemezzo Dayane , Sanada Luciana
Published: November 2023

Comparar o tempo de exposição a telas de lactentes entre os períodos pré e durante a pandemia da

COVID-19 e averiguar fatores relacionados a exposição de tela durante esse período. Responderam

ao “Questionário tempo de exposição a telas”, 63 responsáveis de lactentes, em dois períodos: pré e

durante a pandemia COVID-19. Para a comparação entre os períodos, foi utilizado o teste de Wilcoxon

Rank. Durante a pandemia da COVID-19, aumentou-se significativamente o tempo de telas, passando

de mediana de 4 para 7 horas semanais, destacando-se a televisão como dispositivo mais utilizado.

Observou-se a correlação entre idade do lactente e tempo de exposição a telas. Houve aumento do

tempo de exposição a telas durante a pandemia da COVID-19 nos lactentes avaliados. O tempo total

de telas apresentou uma correlação proporcional com a idade nos períodos avaliados, porém não se

correlacionou com a realização de home-office dos responsáveis.
A new ghrelin receptor antagonist, agrelax, reduces emotional overeating caused by the stimulation of the lateral hypothalamus reward zone in well-fed rats
Authors: Lebedev Andrei A. , Bychkov Evgeny R. , Lukashkova Valeria V. , Lebedev Viktor A. , Efimov Nikolai S. , Shabanov Petr D.
Published: November 2023

BACKGROUND: Ghrelin receptor antagonists hold promise for the treatment of eating disorders. The reward zone of the lateral hypothalamus has been proposed as a target for mediating the effects of the ghrelin system in emotional overeating.
AIM: This study aimed to evaluate the effects of a new ghrelin receptor antagonist, agrelax, on emotional overeating induced by the stimulation of the reward zone of the lateral hypothalamus in well-fed rats.
MATERIALS AND METHODS: Male Wistar rats were trained to self-stimulate in a Skinner box. After training, a feeder was placed in the Skinner box, and a food-conditioned reflex was developed in the rats for 5 days. Then, the reaction of food self-deprivation, i.e., behavior under conditions of choice of self-stimulation or food intake, was assessed.
RESULTS: The reaction of food self-deprivation when the animals did not approach the feeder was 10% of the threshold current. Self-stimulation of the lateral hypothalamus with a threshold current caused numerous approaches to the feeder and food intake. Sulpiride, a dopamine D2/D3 antagonist (5 and 20 mg/kg ip), administered to well-fed rats reduced both feeding behavior and the intensity of self-stimulation in the food self-deprivation test at threshold currents. The ghrelin receptor antagonists [D-LYS3]-GHRP-6 and the novel antagonist agrelax (1 µg/µL, 20 µL intranasally) also reduced both feeding behavior and the intensity of self-stimulation under these conditions.
CONCLUSIONS: Ghrelin and dopamine receptors are involved in emotional overeating. Agrelax, a novel ghrelin receptor antagonist, reduces emotional overeating induced by the activation of the lateral hypothalamic reward system. Because emotional overeating is strongly associated with clinical eating disorders such as bulimia and binge-eating disorder, the use of ghrelin antagonists to treat and prevent this problem is promising.
KIDEMLİ BİR OSMANLI ASKERİNİN GÖZÜYLE SUDAN: ÖMER KÂMİL PAŞA NIN SÛDÂN-I MISRÎ ADLI ESERİNE GÖRE MEHDİ AYAKLANMASI VE İNGİLİZLER
Authors: GÖKGEDİK İsa
Published: November 2023

Adana, Tarsus arasındaki bölgenin köklü ailelerinden biri olan Menemencioğulları'na mensup Ömer Kâmil Bey'in Sûdân-ı Mısrî adlı eseri Osmanlı Devleti'nin XIX. yüzyıl Sudan’ını nasıl tanımladığı ile alakalı önemli bilgiler ihtiva eden kaynak eser hüviyeti taşımaktadır. Erkân-ı harbiye binbaşılarından Ömer Kâmil mesleği olan askerlik açısından yaptığı incelemelere bazı kısa bilgiler ilave ederek eserini kaleme almıştır. Afrika tarihi hakkında Osmanlılar tarafından ortaya konulan telifatın arttığı bir dönemde kaleme alınmasıyla dikkate değer olan bu eser oldukça zayıf olan mevcut literatürün önemli parçalarından birini teşkil etmektedir. Bu eserde Sudan'ın coğrafyası, tarihi, idari bölgeleri, şehirleri, nüfus yapısı, Mısır Hükûmeti'nin durumu, Mehdi isyanı, İngilizlerin faaliyetleri vb. konularda değerli bilgiler aktarılmaktadır. Ömer Kâmil bölgenin sahip olduğu karakteristik yapıyı, öne çıkan hususiyetlerini ve coğrafyanın sağladığı stratejik konumu akıcı bir üslupla anlatırken kendi dönemindeki gelişmelere de geniş bir yer ayırmıştır. Bu çalışmada, önemli bir kaynak olmasına rağmen günümüz araştırmalarında yeterli ilgiyi görmeyen Sûdân-ı Mısrî'nin söz konusu muhtevası tenkitli bir şekilde ve tarihî açıdan değerlendirilecektir. Ayrıca Ömer Kâmil'in tercümeihâli ve bu eseri ortaya koymasındaki saikler açığa çıkarılmaya çalışılacaktır.
LEFKOŞA (KIBRIS) MEVLEVİHANESİNİN KURULUŞU VE İLK VAKIFLARI
Authors: DEMİRYÜREK Mehmet
Published: November 2023

Kıbrıs’ın 1570 yılındaki fethini izleyen yaklaşık 30 yıl içinde Ada siyasal, sosyal, ekonomik ve dinî bakımlardan kurumsallaşma ve görünüm itibarıyla tam bir Osmanlı adası oldu. Lefkoşa bu değişimi en iyi yansıtan şehirlerden biriydi. Beylerbeyleri, Lefkoşa kadıları ve müftüleri bu şehirde ikamet ettiler. Mahalleleri, sakinleri, camileri, mescitleri, çeşmeleri, hanları ve hamamlarıyla Lefkoşa bir Türk-İslam şehri hüviyeti kazandı. Cami, mescit, han, hamam vb. gibi tesislerin devamlılığını temin etmek için birçok vakıf kuruldu. Kapsam ve etkinlik açısından Sultan II. Selim Vakfı ile Lala Mustafa Paşa Vakfı şehrin sosyal ve ekonomik hayatında önemli rol oynadı. Ayasofya Camii (Selimiye), Arap Ahmet Paşa Camii, Bedesten ve Mevlevi Tekkesi şehrin en önemli Türk-İslam simgeleri arasında yer aldı. Bu çalışmanın amacı sözü edilen simgelerden birisi olan Lefkoşa Mevlevi Tekkesinin kuruluş tarihi ile ilgili bilgileri KKTC Millî Arşiv ve Araştırma Dairesi belgeleri ile Osmanlı Arşiv kaynakları temelinde yeniden tartışmak ve değerlendirmektir. Çalışma Lefkoşa Mevlevihanesinin kuruluş tarihi için yeni bir tarihi gündeme getirecek, ilk gelir kaynaklarını ortaya çıkaracak ve böylece hem Kıbrıs tarihine hem de hem söz konusu kurumun tarihine katkıda bulunulmuş olunacaktır.
SIRBİSTAN IN PRİŞTİNE DEKİ İLK KONSOLOSU LUKA MARİNKOVİĆ İN ÖLDÜRÜLMESİ (1 TEMMUZ 1890)
Authors: OLGUN Said
Published: November 2023

1877-1878 Osmanlı-Rus Harbi sonrası imzalanan Berlin Antlaşması ile bağımsız bir devlet hâline gelen Sırbistan, 1887 yılından itibaren Osmanlı toprakları içerisinde yer alan Makedonya coğrafyasının önemli şehirlerinde temsilcilikler kurmaya başlamıştır. Sırplar, Üsküp, Selânik ve Manastır’da kurmuş oldukları konsoloslukların ardından 1889 yılında Priştine Konsolosluğunu kurmuş ve konsolos vekili olarak Luka Marinković’i tayin etmişlerdir. Böylece Eski Sırbistan olarak nitelendirdikleri alandaki varlıklarını ve etkinliklerini artırmaya çalışmışlardır. Bu çalışmada ilk olarak Sırbistan’ın Makedonya’daki diplomatik örgütlenmesi ve bunun aşamaları, Marinković’in Priştine’ye konsolos vekili olarak tayin edilmesi ve mahallî idareyle ilişkileri üzerinde durulmuştur. Ardından Marinković’in öldürülmesi, cenaze merasimi, zanlıların yargılanması ve Sırbistan hükûmetinin Osmanlı Devleti’nden tarziye ve tazminat talepleri üzerinde durulmuştur. Osmanlı arşiv belgeleri üzerinden yapılan bu çalışmada Sırbistan’ın Priştine’deki ilk konsolosu Marinković’in öldürülmesi ve bu hadisenin Osmanlı Devleti ile Sırbistan arasındaki ilişkilere yansıması incelenmeye çalışılmıştır.
Methotrexate-induced multi-organ chronic toxicity in a rheumatoid arthritis patient: a case report
Authors: Kallur Nikitha , Akhiljith  , Antony Nimna Rose , Neeralagi Manjunath
Published: November 2023

This case report highlights the clinical presentation, diagnosis, and management of a 48-year-old female diagnosed with rheumatoid arthritis (RA) who developed toxicity due to prolonged use of methotrexate (MTX) in combination with other immunomodulatory drugs. The patient exhibited erythematous rashes, skin peeling, angular stomatitis, oral candidiasis, symptoms of acute gastroenteritis and pancytopenia. This report discusses the importance of monitoring, managing polypharmacy in patients with chronic diseases, to prevent adverse events and management of drug-induced toxicity in RA patients and improve patient outcomes.
Evidence-based assessment of male-only infertility: prevalence and associated risk factors in Port Harcourt metropolis, Rivers State, Nigeria
Authors: Elekima Ibioku , Aworu Aminayanate M. , Brown Holy , Brisibe Ngozi , George-Opuda Ibitoroko M. , Waribo Helen A. , Ben-Chioma Adline E. , Bartimaeus Ebirien-Agana S.
Published: November 2023

Background: Male infertility is the condition in which a male is unable to establish pregnancy in a fertile woman over 12 months of unprotected sexual intercourse. In this study, the prevalence of male-factor infertility and some associated risk factors in Port Harcourt, Rivers State was carried out.
Methods: The study design was a case-controlled randomized one, in which semen specimens were collected from case and control groups randomly amongst males visiting urology/fertility clinics by masturbation after 3 days of abstinence. A total of 276 males indicated interest to participate in study of which 193 male subjects were recruited.
Results: The result showed that 20.8% were azoospermic, 27.4% were oligospermic, 23.7% were asthenozoospermic, 27.9% oligoasthenozoospermic, 15.1% teratozoospermic, 19.4% asthenoteratozoospermic, and 12.9% oligoasthenoteratospermic. Furthermore, the microbial quality of the semen assessed indicated the prevalence of scanty, moderate, and heavy growth as 12.5%, 9.3%, and 7.3% respectively. Likewise, organisms isolated and identified were Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, and mixed growth of staphylococcus aureus, and Escherichia coli with a prevalence of 18.2%, 5.6%, 2.0%, 1.04%, and 2.6% respectively. Civil servants had the highest prevalence of 20.8% followed by artisans with 11.9%. The prevalence of primary and secondary infertility was observed to be 30.1% and 18.1% respectively.
Conclusions: Male-only factor infertility is on the increase and occupations that are accompanied by prolonged sitting, sedentary work style, or working in or close to high-temperature sources as seen in civil servants and welders (artisans) were observed to be more prone to male-only factor infertility.
Clinical picture of acute post-streptococcal glomerulonephritis in children at Ruteng hospital
Authors: Ongo Maria Y. R. D. , Putri Natasha A. , Naur Octavini M.
Published: November 2023

Background: Acute post-streptococcal glomerulonephritis (PSGN) is the main cause of acute nephritis in children, globally reaches more than 470,000 cases per year, 97% of which occur in developing countries. Sublinical cases are 4 times more common than symptomatic, so reports on the incidence of acute PSGN are very limited.
Methods: This study used a descriptive retrospective method from medical records at RSUD Ruteng from January to June 2023. Data were analyzed using the statistical package for the social sciences (SSPS) 22 program.
Results: Results of the study were obtained as 37 pediatric patients with acute PSGN. The patients age ranged 4-17 years with an average 9 years, 51.4% women and 48.6% men. Most cases occur after respiratory tract infections (75.7%). Symptoms of edema and hypertension (89.2% stage I and 10.8% stage II) was found in all patients and become the reason why patients come. Patients experienced macroscopic hematuria 16.2%. The laboratory test showed 100% microscopic hematuria, proteinuria in 72.1% and ASTO titer increased by more than 200 IU in all patients. Eleven patients with complications, acute renal failure (24.3%), hypertension encephalopathy (5.4%) and 1 patient with pulmonary edema. The average length of stay is 8 days (3-22 days).
Conclusions: The incidence of acute PSGN at RSUD Ruteng within 6 months is quite high. Acute PSGN in children causes severe complicationsand longer treatment. The prevention is needed to care about the importance of clean and healthy living behavior.
Effect of manually assisted cough technique on cough strength in extubated patients with organophosphorus poisoning
Authors: Nandre Bhagyasha Shamkant , Gunjal Sambhaji B.
Published: November 2023

Background: Organophosphate (OP) ingestion is one of the most common emergencies treated at poisoning control centers worldwide. In an extubated patient with OPP, the abdomen and chest muscles are affected, it also affects a person's ability to breathe on their own, rendering them dependent on a ventilator. Intubation weakens the abdominal muscles and diaphragm making it difficult to cough and clear the chest. A manual cough-assisted technique is used to enhance the cough strength, to help with the clearance of secretions it can be carried out in lying, side-lying, or sitting positions. Objectives were to find the effect of a manually assisted cough (MAC) technique on cough strength (Peak cough flow (PCF) and maximum expiratory pressure) in extubated patients with organophosphorus poisoning. 
Methods: According to the selection criteria, 50 participants extubated with organophosphorus poisoning were included. A baseline assessment was done of all individuals and MAC techniques were given. outcome measures were assessed with PCF meter and PEmax manometer. MAC techniques are given for 1 week to each patient.
Results: Pre and post-intervention PCF and maximal expiratory pressure (MEP) was compared and analyzed with paired t tests and which shows an extremely significant difference with p<0.0001 which indicates significant improvement in cough strength after 1 week of MAC techniques.
Conclusions: This study concluded that the MAC. Technique improved the cough strength (PCF and MEP) in extubated patients with organophosphorus poisoning.
Knowledge, attitudes and practice among healthcare workers towards COVID-19 in a tertiary care centre in north India
Authors: Mahajan Neha , Saroch Neelisha , Sharma Pooja , Gupta Anish
Published: November 2023

Background: Coronavirus disease pandemic has affected the entire world and till date, there is no definitive cure for it with prevention of infection and knowledge about the disease being the only proven effective methods to contain it. Healthcare workers (HCWs) are highly susceptible to getting infected and their knowledge about COVID-19 infection has been known to be inversely proportional to the rates of COVID-19 infection.
Methods: Cross-sectional questionnaire-based study assessing knowledge, attitude and practices towards COVID-19 preventive measures was carried out amongst HCWs at a tertiary care hospital in North India.
Results: Around 95% of HCWs had received training regarding COVID-19 infection and more than 95% HCWs had adequate knowledge about COVID-19 infection. More than 95% HCWs experienced anxiety and fear while monitoring and treating COVID-19 patients. 85% HCWs felt that there is sufficient awareness in the society regarding COVID-19 infection. Most of the respondents followed correct practices for avoidance of COVID-19 infection with around 90% respondents using face masks and practicing frequent hand washing. Social distancing and avoidance of large gatherings was practiced by around 95% respondents. More than 95% respondents had either taken COVID-19 vaccine or wish to take it.
Conclusions: The study suggested that the majority of HCWs had good knowledge and positive attitude toward COVID-19 but there are still some lacunae present in the knowledge regarding prevention of COVID 19 infection. Further education and training are required for HCWs so as to fight COVID and prevent its spread in a better way.
Inclusion of carbohydrate antigen 242 in addition to carbohydrate antigen 19.9 in serological workup of carcinoma gall bladder: a case series analysis
Authors: Misra Mrigank , Mishra Medha , Agarwal Preeti , Gupta Sameer , Anand Akshay , Ali Wahid , Maurya Malti K. , Singh Ajay K.
Published: November 2023

Background: Common antigenic pool is seen because of shared embryonic origins of gall bladder cancer (GBC) and pancreas. Hence, we analyzed the role of serum carbohydrate antigen 242 (CA242) which has been studied in pancreatic cancer, in GBC. The objectives were to identify whether serum CA242 provides added advantage in diagnosis of GBC when compared to controls and to determine its cut-off value.
Methods: Serum CA 19-9 level was determined by chemiluminescent micro particle assay and CA242 by enzyme linked immunosorbent assay (ELISA) of age matched cases and controls.
Results: Total enrolled patients were 83 including 10 (11.7%) healthy volunteers, 22 (25.9%) chronic cholecystitis cases, and 53 (62.4%) patients with histological evidence of carcinoma. Mean age of presentation of GBC was 51.64 SD10.88 years with F: M ratio of 5.6:1. Pain (90.6%, 48/53) accompanied with jaundice was significantly associated with GBC well reflected by significantly raised serum total bilirubin (p=0.011), direct bilirubin (p=0.008) along with alkaline phosphatase levels (p=0.001). Significantly higher median value of CA 19-9 and CA242 was observed in GBC when compared to CC and healthy volunteers (p<0.001) with a significant correlation between tumor size (>2.5 cm) and serum levels of CA242. The best cut-off limit for CA242 was 45.25 IU/ml. The specificity for carcinoma diagnosis increased to 100% when CA242 was included along with CA 19.9 in serological estimation.
Conclusions: We recommend that CA antigen 19-9 may be complimented with CA242 for serological identification of malignancy in the gall bladder.
An unusual coalition of medullary nephrocalcinosis with a novel genotypic variant of Alport syndrome type-1
Authors: Pradhan Poonam , Kapat Aritra , Mandal Asok K. , Bala Ashok K.
Published: November 2023

Alport’s syndrome is a type of inherited disorder of the basement membrane characterized by a spectrum of phenotypes ranging from progressive renal injury to varied extrarenal manifestations comprising auditory and ocular abnormalities. Here in, we present a 3-year-old child born out of nonconsanguineous marriage who presented with fever, intermittent microscopic haematuria, and recurrent gross haematuria, proteinuria with normal auditory brainstem response and ocular slit lamp examination findings. Renal biopsy yielded normal light microscopy and immunofluorescence study whereas minimal changes in the glomerular basement membrane (GBM) collagen were detected on electron microscopy, suggesting possibilities of Alport’s syndrome. Ultrasonographic renal imaging yielded the presence of bilateral medullary nephrocalcinosis. Angiotensin converting enzyme inhibitors along with angiotensin receptor blockers were used to curb the disease progression. A final clinical exome sequencing corroborated the phenotype with a diagnosis of Alport’s syndrome type-1 linked to a novel pathogenic variant c.1892dup (p.Gly632ArgfsTer2) showing hemizygous single base pair insertion/duplication in COL4A5 gene. To the best of our knowledge, this unusual association of Alport’s syndrome with medullary nephrocalcinosis has not been reported worldwide in any previous medical literature making this report a primi one.
Kartagener syndrome with renal amyloidosis: a case report
Authors: Naredi Mohit , Patira Nilesh , Dangar Hiren , Mehta Urvansh
Published: November 2023

Kartagener syndrome is a rare disorder caused by defective ciliary function. It is described as a triad of cystic bronchiectasis, chronic sinusitis, and situs invertus. Renal involvement, although uncommon, is reported. The available evidence in literature consists of case reports and series, which describe various patterns of renal involvement. We hereby describe a case of a young female who presented with advanced renal failure and hypertension requiring urgent hemodialysis. On evaluation, she was found to have the classic triad of bronchiectasis, chronic sinusitis, and situs invertus leading to the diagnosis of Kartagener syndrome. On workup for the cause of renal failure, we found membranoproliferative glomerulonephritis due to amyloidosis secondary to bronchiectasis. This is a rare association and only 1 case has been reported in the available literature. There are no consensus guidelines regarding treatment of this condition, due to paucity of available data and because of rarity of the condition. This disease should be reported to augment the available literature.
Population-Genetic History of China in the Context of the East Asian Population History
Authors: Konkov Andrey S.
Published: November 2023

The territory of modern China was a zone of active population transformations from the time of its occupation by human species. There was the formation zone of the progenitors of all Mongoloid populations associated with the eastern trunk of non-Africans. The most ancient group is associated with the population of Tianyuan cave (田園洞). The basal steam split, after Tianyuan branch separation into two clusters of southern and northern populations. The north groups formed a gene pool base for the modern population of the northern half of China, Japan, Korea, as well as Mongolia, Siberia, and America. The southern groups formed a gene pool core for the population of Indochina, Indonesia, eastern Oceania. From the beginning of the Neolithic era, two-way interaction begins between both groups. During the agricultural spread, people from the region of the upper Yellow River actively settled in Tibet, the southwestern provinces of China, the lower reaches of the Yellow River, forming the basis of the gene pool of modern Tibetans, other Tibetan-Burmans and progenitors of the Han. Also, the migrants from the valley of Yellow River influence the population of the western Liao River, associated with another subgroup of the northern Mongoloid cluster. And the basin of this river, this population inhabits the Korean Peninsula, and from there to the Japanese archipelago.
In historical time, especially in the Jin, Tang and Song eras, the penetration of northerners south of the Yellow River intensified. It absorbs local groups and affects the gene pools of local Sino-Tibetan and Hmong-Mien groups that have escaped assimilation. At the same time, the southern groups of Han Chinese also receive a noticeable admixture from the southern Mongoloid groups of the southern cluster. The arrival of the Han Chinese probably causes the outflow of part of the Tibeto-Burman groups to northeast India. The invasions of the steppe nomads did not change the gene pool of China. On the contrary, the resettlement of Han farmers in the steppe left a noticeable admixture in the population of Mongolia from the Xiongnu era to the present. Thus, the population of China since ancient times has not only a turbulent internal population history but had been influencing since the earliest epochs to rest of the population of the Inhabited parts of the World like Siberia, both Americas, India, South-East Asia and Oceania.
From the Art of Space to the Art of Understanding: The “Universal Language” Exhibition Project of the Pushkin State Museum of Fine Arts
Authors: Goryaeva Tatiana
Published: November 2023

The Pushkin State Museum of Fine Arts “Universal Language” exhibition project of the was dedicated to the idea of the world’s unity in its diversity of languages and cultures, and the desire of mankind to find a common language. This exhibition is primarily about the importance of the diversity of human communication, about finding mutual understanding through the wisdom of creeds and travel, through diplomacy and everyday rituals. This multilingualism was represented by a variety of scripts with traditions dating back thousands of years, deciphered texts, characters, and hieroglyphs, as well as very young language systems that emerged only a few decades ago. The treasures of Russian museums, archives, libraries, and academic institutes, many of which were first extracted from the vaults, allowed us to make an imaginary journey through countries and epochs, to look not only many centuries ago, but also to see in this reflection of ourselves today.
Not Just Hokusai: Three Waves of Japanese Culture in the West. Part I
Authors: Katasonova Elena
Published: November 2023

For more than a century and a half, the fashion for Japanese art has been one of the most important trends in Western culture. The famous engraving by Katsushika Hokusai “The Great Wave in Kanagawa” (1830–1832) from the famous series “Thirty-Six Views of Mount Fuji” became its peculiar symbol. But how could it happen that this drawing, created by a Japanese artist for his own compatriots many years ago, sunk so deeply into the souls of Europeans? There are several answers to this question, and one of them boils down to the fact that the waves depicted in the engraving represent the opening of Japan to the outside world, from which the country was separated for more than two centuries (1641–1853).
About the Arabian poet and hanif Umaiya ibn Abī s-Salt in al Masoudi’s Work Meadows of Gold and the Mines of Germs (d. 956)
Authors: Mikulski Dimitri V.
Published: November 2023

Umayya b. Abu 'l-Salt is one of the remarkable personalities of the Arabic historical tradition about Pre-Islamic Arabia. Extremely peculiar are the materials, that are dedicated to him in the «Meadows of Gold and the Mines of Germs» by the great Arabic historian, geographer and man of letters al-Mas‘udi (d. 956). The said work is the main book by the mentioned Author. In organizing these materials al-Mas‘udi displays a high degree of literary skill and artistic taste.
The Unread Letters of Sympathy and Support to the Crown Prince Nicholas (New Data on the incident in Otsu, April 29 / May 11, 1891)
Authors: Pyasetsky Vladimir
Published: November 2023

The paper analyses the group of letters from the trip of the Crown Prince Nicholas to Japan and the attempted murder of 1891 in the city of Otsu (Shiga prefecture, Japan). The author, based on letters and other written materials, was able to describe the situation of the incident and analyze detailed features of the structure of the available (not all) letters. This shows to whom, in what form and in what style the presented letters and the envelopes they were in. The preliminary conclusions of the consideration of the “gifts of the ‘Memory of Azov’ cruiser”, both historical value and material evidence, are given. As illustrations, 6 scans of envelopes are attached to the article, in which there were letters of sympathy and support after the assassination attempt.
Japonisme in Russian Printed Graphics at the End Of the 19th – the Beginning of the 20th Century
Authors: Chernysheva Anna
Published: November 2023

Japonisme is a complex phenomenon, based on the pervasion of Japanese culture into Western culture. Russian artists comprehended it mainly in Europe at the same time as the latest trends in Western art. In their memoirs, the names of Hokusai, Hiroshige and Utamaro are often found: The acquaintance with the engravings of these masters had a great influence on the visual language of a generation of artists in Europe and Russia. Immersion in the technique of Japanese ukiyo-e woodcuts led to experiments, the result of which was the reception by Russian artists of several principles of graphic interpretation of depicted objects, spatial structure, and composition. One of the first Russian artists, who began to work in color engraving was M. V. Yakunchikova. In her works a fusion of various trends is noticeable, among which are the innovative ideas of European artists, and the influence of Japanese woodcuts, and the aestheticism of the “Mir Iskusstva”. The main features of Yakunchikova’s etchings are the conciseness and restraint of the compositions, the absence of excessive detail, the smoothness of the lines and the silhouette of the construction. A. P. Ostroumova-Lebedeva enriched Russian woodcut with color and abandoned the stroke, putting the silhouette and the generalized line in the first place. Her works are characterized by subtle lyricism at the same time as a strictly built composition. V. D. Falileev also worked in the technique of linocut. He created several talented works that demonstrated her wide visual capabilities. Along with recognized masters such as Yakunchikova, Ostroumova-Lebedeva and Falileev, lesser-known masters such as N. N. Zeddeler and A. P. Somova-Zeddeler. Until recently their works did not attract the attention of researchers, but at the beginning of the twentieth century their work was an integral part of artistic life. Despite the presence of a fairly large number of publications devoted to Japonisme and its influence on European art, this topic remains insufficiently studied in Russian art. Japonisme has become one of the important features of the Art Nouveau style, which is characterized by spatial convention, silhouette construction, the rhythm of color spots and other techniques aimed at creating laconic and decorative artistic images.