bluuebunny/crossref_metadata_2025 huggingface dataset:
IoT edge based framework for sybil and buffer overflow detection
Authors: Pandey Utpal , Chaurasia Brijesh Kumar
Published: June 2022

The Internet of Things (IoT) is gradually spreading across the globe, offering a wide variety of opportunities across every part of our lives. Unfortunately, the Internet of Things comes with several information technology flaws and exploits. As the number of security vulnerabilities continues to rise, cybersecurity remains a serious problem for every business in cyberspace. In recent times thousands of zero-day attacks are known to exist. As a result, the addition of new attacks emerges regularly several protocols, mostly from the IoT. There are minor modifications to previously reported cyberattacks. This suggests that even advanced mechanisms like basic machine learning systems have a hard time identifying anomalies. IoT applications pose various threats to businesses, according to security experts. Because of the widespread acceptance of IoT devices, their variety, standardization challenges, and inherent versatility, businesses need an intelligent mechanism capable of the detecting unauthorized IoT devices automatically and connected to their networks. In this study, a machine learning approach is used to identify unauthorized IoT devices by detection of sybil and buffer overflow attack among IoT devices infrastructure. The CNN technique focuses on detecting the attack or activity of any malicious node, as well as attempting to resolve the problem. In this research, CNN, a deep learning technique, was applied for extracting features from the network traffic data to accurately identify malicious IoT devices.
Polarization-independent graphene-based electro-absorption modulator using semi-ellipsoid HfO2 slot waveguide
Authors: Dalvand Hanye , Nikoufard Mahmoud , Zangeneh Hamid Reza
Published: June 2022

In this article, a wideband polarization-independent graphene based electro-absorption modulator (EAM) operating in the wavelength range of 1400 nm–2000 nm is proposed. The proposed modulator consists of a slot waveguide comprising two semi-ellipsoid hafnia (HfO2) layers with a slot width of 100 nm embedded in a silicon dioxide (SiO2) substrate, caped with a graphene layer, and two electrodes on both sides. The key advantages of this structure include improvements at a wavelength of 1550 nm in polarization-sensitive loss (PSL ≤ 0.11 dB), propagation length of 6170 µm, 3dB bandwidth of 500 GHz, mode power attenuation of 7×104 dB/m, and insertion loss of -23.22 dB/µm. Moreover, the effects of wavelength on PSL and radius on extinction ratio were investigated, resulting in tunable PSLs in “OFF” and “ON” states at a wavelength of 1550 nm. Thus, the proposed EAM can be potentially utilized in electro-optical (EO) switching.
Spontaneous ventral hernia through the rectus abdominis muscles: a case report
Authors: washiro mitsutsune Benedict , Kitahara Takuya , Yanagisawa Nobuo , Narita Jun , Danzuka Takao , Ohtsuka Masayuki
Published: June 2022

Background A hernia is a condition in which tissues or organs are abnormally protruding through a defect in the surrounding wall. We experienced a rare spontaneous ventral hernia that penetrated the right transverse abdominal fascia and rectus abdominis muscles. Case presentation A 92-year-old woman was admitted to our hospital with major complaints of right abdominal pain and some quadrant mass. She had no history of trauma and lower abdominal surgery. Computed tomography revealed that a protrusion of the hernia from the right lower abdominal wall. The hernia contents were small intestine, which penetrated the transverse abdominis fascia and rectus abdominis muscles. The herniation has been manually reduced. Elective surgery was performed 3 days later. The intraoperative findings indicated that the hernia sac was located around the middle of the rectus abdominis muscles in the right lower abdominal wall. Hernioplasty was performed using Bard Light PerFix Plug®. The patient fully recovered and was discharged 8 days after surgery. No recurrence was identified for 42 months during patient follow-up. Conclusions We presented a rare case of hernia, which was protruded through the rectus abdominis muscles. Intrinsic anatomical weakness of the abdominal wall and age-related muscle atrophy might have caused this rare hernia. This case report provides clinicians useful information for accurate diagnosis and successful treatments of this type of hernia in the elderly, and contributes to identifying the anatomical features of some rare ventral hernias.
Targeting Human Thymidylate Synthase: Ensemble-based Virtual Screening for Drug Repositioning and the Role of Water
Authors: MTEREMKO DENIS , Chilongola Jaffu , Paluch Andrew S. , Chacha Musa
Published: June 2022

A drug repositioning computational approach was carried to search inhibitors for human thymidylate synthase. An ensemble-based virtual screening of FDA-approved drugs showed the drugs Imatinib, Lumacaftor and Naldemedine to be likely candidates for repurposing. The role of water in the drug-receptor interactions was revealed by the application of an extended AutoDock scoring function that included the water forcefield. The binding affinity scores when hydrated ligands were docked were improved in the drugs considered. Further binding free energy calculations based on the Molecular Mechanics Poisson-Boltzmann Surface Area method revealed that Imatinib, Lumacaftor and Naldemedine scored − 130.7 ± 28.1, − 210.6 ± 29.9 and − 238.0 ± 25.4 kJ/mol, respectively, showing good binding affinity for the candidates considered. Overall, the analysis of the molecular dynamics trajectory of the receptor-drug complexes revealed stable structures for Imatinib, Lumacaftor and Naldemedine, for the entire simulation time.
Assessment of farmers’ socioeconomic and conservation practice towards watershed management in the South West of Ethiopia
Authors: Woldeab Bizuneh , Ambelu Argaw , Beyene Abebe , Efrem Zewdu , Deribe Siyoum , Megersa Moa , Alemu Tibebu , Mereta Seid Tiku
Published: June 2022

Background
Watershed resource conservation is important for the wellbeing of the environment and communities. Understanding farmers’ socioeconomics and watershed conservation practices help in determining necessary interventions to address environmental threats. The study area is important at regional and national level due to the hydroelectric dam of the mega power project. This study deals with the farmers’ socio economic and conservation practices of Gilgel Gibe watershed. The study targeted 305 households in 4 districts of Jimma Zone surrounding the Gilgel Gibe Reservoir I. Semi-structured questionnaire was administered via interviews and focus group discussions led by trained survey interviewers.
Result
The findings of the study indicated that majority of farmers in the watershed have adequate knowledge, positive attitude and bad practice towards watershed conservation. To achieve better means of subsistence and improve their living condition farmers are forced to put stress on natural resource, degrading watershed and increase pollution loads that affect water quality of tributaries and reservoir.
Conclusion
Based on the present scenario, we forwarded stakeholders to establish team from the elders, officials at woreda and zonal level to initiate commitment, coordinate conservation activity and promote households’ income generating activities at homestead level like conservation agriculture.
Protein arginine methyltransferase 7 suppresses migration and invasion in prostate cancer cells in vitro
Authors: Hu Ping , He Yanyan , Sun Xinyue , Chen Ping
Published: June 2022

Protein methyltransferase arginine 7 (PRMT7) is the sole member among protein arginine methyltransferases (PRMTs) that participates in the monomethylarginine formation involved in tumor biology, DNA damage repair, and development. In this study, we report that PRMT7 is downregulated in prostate cancer cell lines in vitro and its overexpression suppresses migration and invasion in the prostate cancer cell lines LNCaP and PC3, as determined by wound healing, migration, and invasion assays. To identify the potential downstream mediator of PRMT7, we performed whole-genome transcriptome and proteome sequencing analysis, and found that the metastasis suppressor gene KISS1R was up-regulated both at the transcriptional and translational level by PRMT7. Knockdown of KISS1R rescued the tumor-suppressive phenotype. Collectively, we uncovered the anti-oncogenic role of PRMT7 in prostate cancer cells and further demonstrated that KISS1R is a downstream effector molecule of PRMT7 in modulating tumor cell migration and invasion and PRMT7 may be effective target for the clinical treatment of prostate cancer.
RETRACTED: Improved conditionally replicative adenovirus delivery system against hepatocellular carcinoma by armed with bispecific T-cell engager
Authors: Yuan Xiangfei , Lu Yang , Yang Yuanyuan , Tian Wencong , Fan Dongmei , Liu Ruoqi , Lei Xiaomin , Xia Yafei , Yang Lei , Yan Shu , Xiong Dongsheng
Published: June 2022

The authors have requested that this preprint be removed from Research Square.
Oral or intranasal immunization with recombinant Lactobacillus plantarum displaying head domain of Swine Influenza A virus hemagglutinin protects mice from H1N1 virus
Authors: Zhang yufei , Yang Li , Zhang Jiali , Huang Kun , Sun Xiaomei , Yang Ying , Wang Ting , Zhang Qiang , Zou Zhong , Jin Meilin
Published: June 2022

BackgroundSwine influenza A virus (swIAV) is a major concern for the swine industry owing to its highly contagious nature and acute viral disease. Currently, most commercial swIAV vaccines are traditional inactivated virus vaccines. The Lactobacillus plantarum-based vaccine platform is a promising approach for mucosal vaccine development. Oral and intranasal immunisations have the potential to induce a mucosal immune response, which confers protective immunity. The aim of this study was to evaluate the probiotic potential and adhesion ability of three L. plantarum strains. Furthermore, a recombinant L. plantarum strain expressing the head domain of swIAV antigen HA1 was constructed and evaluated for its ability to prevent swIAV infection. ResultsThe three L. plantarum strains isolated from healthy pig faecal samples maintained the highest survival rate when incubated at pH 3 and at bile salt concentration of 0.3 %. They also showed high adherence to intestinal cells. All three L. plantarum strains were monitored in live mice, and no major differences in transit time were observed. Recombinant L. plantarum expressed swIAV HA1 protein (pSIP401-HA1-ZN-3) and conferred effective mucosal and systemic immune responses in the intestine as well as in the upper respiratory airways of mice. In conclusion, the oral and intranasal administration of L. plantarum strain pSIP401-HA1-ZN-3 in mice induced mucosal immunity and most importantly, provided protection against lethal influenza virus challenge. ConclusionIn summary, these findings suggest that the engineered L. plantarum strain pSIP401-HA1-ZN-3 can be considered as an alternative approach for developing a novel vaccine during an influenza A pandemic.
Modified Omar sign for the clinical diagnosis of unilateral foraminal stenosis associated with disc prolapse.
Authors: ELDANASORY OMAR
Published: June 2022

Objectives: A retrospective study analyses the validity of Modified Omar's Sign for the diagnosis of unilateral lumbar foraminal stenosis with disc prolapse.Methods: This study analyses 250 patients with unilateral sciatic pain, between 2011 and 2020.All the data obtained from the data base collected from our institution and our private clinics. All patients had a standardized neurological clinical assessment by applying the modified Omar test during their clinical examination, then comparing the clinical findings with the (MRI) imaging findings and comparing the preoperative clinical findings with the postoperative clinical findings. Results: As the modified Omar test was applied during the physical examination, the test was positive for all patients with positive MRI with unilateral lumbar disc prolapse with foraminal stenosis on the same side. The clinical findings also confirmed by the absence of the test after surgical intervention and after nerve root block.Conclusions: The modified Omar test is a test applied during the physical examination for specific diagnosis of lumbar foraminal stenosis of patients having unilateral lumbar disc prolapse. The correlation between clinical and radiological findings confirms the test availability. The absence of the omar sign during the test after surgical intervention, and after nerve root block is considered a sure sign of high sensitivity and specificity of the test. So, the test is a more reliable diagnostic tool for the clinical diagnosis of foraminal stenosis that can be added to the clinical examination sheet. And, for the clinical identification of the efficacy of the surgical treatment and follow-up.
Band degeneration and evolution in nonlinear triatomic chain superlattices
Authors: Gong Chen , Fang Xin , Cheng Li
Published: June 2022

Nonlinear superlattices exhibit unique features allowing for wave manipulations. Despite the increasing attention received, the underlying physical mechanisms and the evolution process of the band structures and bandgaps in strongly nonlinear superlattices remain unclear. Here we establish and examine strongly nonlinear superlattice models (three triatomic models) to show the evolution process of typical nonlinear band structures based on analytical and numerical approaches. We find that the strongly nonlinear superlattices present particular band degeneration and bifurcation, accompanied with the vibration mode transfer in their unit cells. The evolution processes and the physical mechanisms of the band degeneration in different models are clarified with the consideration of the mode transfer. The observed degeneration may occur as the shifting, bifurcating, shortening, merging or disappearing of dispersion curves, all depending on the arrangement of the coupled nonlinear elements. Meanwhile, the dimension of the unit cell reduces, alongside changes in the frequency range and mechanisms (Bragg and local resonance) of the bandgaps. These findings answer some foundamental questions peritinent to the study of nonlinear periodic structures, nonlinear crystals and nonlinear metamaterials, which are of interest to the broad community of physics.
Receipt of subsequent immune checkpoint inhibitors at progression among patients with solid tumors enrolled in clinical trials of adjuvant immune checkpoint inhibitors
Authors: Smith Claire E.P. , Haslam Alyson , Prasad Vinay
Published: June 2022

Purpose: Immune checkpoint inhibitors can induce long-term responses in metastatic cancer, thus determining how many patients on placebo control arms of adjuvant immune checkpoint inhibitors receive these drugs as standard of care at progression is critical to assess if the benefit is truly from adjuvant administration or treatment at any point. Methods: This study included recent clinical trials of adjuvant immune checkpoint inhibitors for solid tumors that gained FDA approval. We determined the number of placebo control patients with progression events, the number who actually received subsequent immune checkpoint inhibitor, and the number who were eligible to receive it. Results: Data was available from 462 placebo control patients who experienced progression in trials of adjuvant immune checkpoint inhibitors. 377 of these control patients were eligible for first line immune checkpoint inhibitors upon progression. 34% (130/377) of eligible control patients received immune checkpoint inhibitors in the first line metastatic setting. In total, 28% (130/462) received immune checkpoint inhibitors, 54% (247/462) were eligible but did not receive it, and 18% (85/462) were ineligible according to currently accepted standard of care.Conclusions: Only 34% of eligible patients in placebo control arms of trials of adjuvant immune checkpoint inhibitors for solid tumors receive these medications upon progression. This is surprisingly low, and suggests that exposure to immune checkpoint inhibitors at all, instead of in the adjuvant setting, could explain the positive effect size of recurrence free survival observed in each of these trials.
The Alteration of Intrauterine Microbiota in Chronic Endometritis Patients Based on 16s rRNA sequencing Analysis
Authors: Chen Qing , Zhang Xiaowei , Hu Qicai , Zhang Wei , Xie Yi , Wei Weixia
Published: June 2022

Background
Chronic endometritis (CE) is a disease of continuous and subtle inflammation occurred in the endometrial stromal area, which is often asymptomatic or present with non-specific clinical symptoms.
Methods
This study investigated the composition and distribution of the intrauterine microbiota of 71 patients who underwent hysteroscopy during the routine clinical inspection of infertility. Among them, patients who diagnosed as chronic endometritis (CE) were allocated into CE group (n = 29) and others into non-CE group (n = 42). There was no significant difference in average age between the two groups. Uterine flushing fluid were collected by the self-developed cervical trocar uterine cavity sampler and performed 16S rRNA gene sequencing.
Results
The alpha diversity in CE group was significantly higher than that in non-CE group (P < 0.05). Firmicutes were the dominant phylum in the non-CE group (72.23%), while its abundance was much lower in CE group (49.92%), but there was no statistical difference between the two groups. The abundances of Actinobacteriota and Cyanobacteria in CE group were significantly higher than in non-CE group (P < 0.05). At genus level, the abundance of Lactobacillus dominated in all samples, which presented lower abundance in CE group (40.88%) than in non-CE group (64.22%). Correspondingly, the abundance of non-Lactobacillus was higher in CE group, among which Pseudomonas and Cutibacterium increased significantly (P < 0.01). Moreover, compared with the non-CE group, the pathways involved arginine and proline metabolism (P = 0.048) and retinol metabolism (P = 0.049) were significantly enriched in CE group, while the metabolism of lipid (P = 0.028) and prenyltransferases (P = 0.046) were significantly decreased in CE group.
Conclusions
In conclusion, certain microbial community was colonized in the uterine cavity, with Lactobacillus as the dominant genera. The structure and distribution of intrauterine microbiota in CE group were different from non-CE group by showing lower abundance of Lactobacillus, and significantly higher abundance of Pseudomonas and Cutibacterium. As a result, the microbial metabolism was also altered in CE groups. This study elaborated the alteration of intrauterine microbiota in the CE patients, which would improve the diagnosis rate of CE and guiding the selection of antibiotic treatment for CE patients.
The expression of the adenosine-pathway markers CD39 and CD73 in salivary gland carcinomas harbors the potential for novel immune-checkpoint inhibition
Authors: Bauer Arthur , Gebauer Niklas , Knief Juliana , Tharun Lars , Arnold Nele , Riecke Armin , Steinestel Konrad , Witte Hanno M.
Published: June 2022

Background
In salivary-gland-carcinomas (SGC), there is only a small fraction of entities that appears to profit from immune-checkpoint-inhibition (ICI). Recent findings connected the activation of adenosine-signaling with a tolerogenic microenvironment. Therefore, the inhibition of adenosine-pathway markers (CD39 and/or CD73) can augment ICI and/or display a novel immunotherapeutic strategy beyond ICI. Here, we assessed the immunohistochemical expression of CD39 and CD73 across a wide spectrum of SGCs.
Methods
In total, 114 patients with SGCs consecutively diagnosed between 2001 and 2021 were assessed for clinicopathological baseline-characteristics and underwent confirmatory histopathological review. Immunohistochemical expression-levels of CD39 and CD73 were assessed by applying the tumor-proportion-score (TPS) and the immune-proportional-score (IPS) comparable to PD-L1 expression analysis in routine clinical practice. Additionally, findings were correlated with PD-L1 expression-levels.
Results
The median age was 60.6 and 51.8% patients were female. The cohort covered a spectrum of eight distinct entities. Advanced-stage disease (UICC/AJCC III/IVA-IVC) at initial diagnosis was present in the majority of patients (64/114). Immunohistochemical-staining revealed positivity for CD39 and CD73 in 48.2% and 21.1% on tumor-cells (TPS ≥ 1%) as well as 46.4% and 42.9% within the immune-cell infiltrate (IPS ≥ 1%), respectively. Further comparative analyses revealed immune-cold entities such adenoidcystic-carcinoma (AdCC), immune-hot tumors such as adenocarcinoma, not otherwise specified (AC (NOS)) and entities with intermediate immunologic features such as acinic-cell-carcinoma (ACC).
Conclusion
Current results indicate entity-specific adenosine-signaling signatures. These findings suggest that the adenosine-pathway plays a decisive role in tumor immunity among the major spectrum of SGCs. Targeting the adenosine-pathway might pose a promising therapeutic option for selected entities.
Has the COVID-19 influenced the patient presentations and therapeutic options for urolithiasis?
Authors: LUO Yijia , REN Hongyan
Published: June 2022

Objective: To identify the influence of COVID-19 on the patient presentations and therapeutic options of urolithiasis resort to hospital during the first year of the pandemic. Methods: A systematic literature review of Pubmed, Embase, Web of Science, Ovid EMBR, and Cochrane library was performed from Jan 2020 to Dec 2021. The PRISMA criteria were followed for article selection. The pooled analysis such as age, gender, stone characters, time of symptom to a hospital visit, therapeutic methods, and length of hospital stay was calculated using the random-effects model. A subgroup analysis of fewer than 45 days since the epidemic was conducted. Results: Twelve retrospective studies were included, and the total number of patients was 4116 patients before versus 3409 during the COVID-19. The patient decreased by 17.2% during COVID. Even with significant heterogeneity in many aspects of comparison, the sensitivity analysis showed the robustness of the results. The patients' age, gender, comorbidity, stone size, and stone location stayed unchanged. But the delay in hospital visits was statistically significant and supported by the elevated white blood count and level of hydronephrosis. Regarding therapeutic options, the rate of medical expulsive therapy & observation, shock wave lithotripsy, and definitive therapy (ureteroscopy lithotripsy, percutaneous nephrolithiasis, and bladder lithotripsy) remained unchanged. There was no death report within the included studies before or during the COVID period. The subgroup analysis of < 45 days shows the likewise results.Conclusion: The impact of the COVID-19 pandemic on patients mainly was canceling or postponing the hospital visit. However, the highest level of emergency cases was similar. Meanwhile, the essential treatment of urolithiasis remained. These demonstrate the limited influence of COVID on urolithiasis during the first year of the pandemic.
Chalcogenide films optical modification by laser influence
Authors: Olkhova Anastasiia A. , Patrikeeva Alina A. , Chapalda Evgenia N. , Sergeev Maksim M.
Published: June 2022

The paper presents the results of studying the effect of continuous laser exposure on the change in the photosensitivity of PbSe films in a narrow spectral range. The result of laser action on PbSe films in the mode of scanning with continuous radiation at a wavelength of 405 nm has been studied. As a result of the photothermal effect on the film structure, reflection and transmission changed in the spectral range 0.3–1.0 µm. At a power density of 121.6 W/cm2, photobleaching of the material and its melting were observed, followed by its destruction, leading to the formation of microcracks. As the power density decreased to 76 W/cm2, photodarkening of the film was observed in the region of laser action. For the modified sections of the film, in this case, a sharp decrease in transmission and reflection was observed. In terms of its optical characteristics, the material approached an absolutely dark body. This modification of the film is especially promising for the photodetection of organic molecules in the form of a gas mixture or liquid.
An Efficient Real-Time Embedded Application Mapping For NoC Based Multiprocessor System on Chip
Authors: KUMAR ARURU SAI , Rao T.V.K Hanumantha , Beechu Naresh kumar reddy
Published: June 2022

The evolution of the components embedded on a single chip is growing faster day by day, resulting in a considerable impact on the performance metrics and communication between the cores in the NoC architecture. So, to overcome such issues, it is important to provide an efficient mapping between the cores, such that the communication between them increases. To improve the performance of a network, throughput and latency also play a significant role. In this research paper, an efficient mapping strategy implemented on the real-time embedded applications named ERTEAM. In this algorithm, based on the minimum Core Average Distance (CAD) the mapping region is finalized, ensuring the overall mapping area reduced. The PE’s mapped according to the minimum communication energy in the selected mapping region. This research evaluated a set of embedded applications, which reveals a reduction in latency at 12.3% against BBPCR and 8.4% against SBMAP. The simulation time reduces at an average of 19% against BBPCR and 9.6% against SBMAP. The throughput increases at an average of 14.5% against BBPCR and 7.8% against SBMAP and reduces the communication energy by 15.6% against BBPCR and 5.2% against SBMAP.
Reference role of middle turbinate axilla in lacrimal sac localization assisted by computed tomographic dacryocystography
Authors: Yang Lihong , Li Hongxun , Yin Zhi , Zhang Lei , Yang Zhenhai
Published: June 2022

Background: The middle turbinate axilla (MTA) has always been used as a stable anatomic landmark for endoscopic surgeons to locate the lacrimal sac on the lateral nasal wall. Yet, little is known about whether the lacrimal sac size will affect the positioning effect of MTA on lacrimal sac. The aim of this study was to investigate the regularity of lacrimal sac size and lacrimal sac localization through the reference position of the MTA on computed tomographic dacryocystography (CT-DCG) images. Methods: A series of 192 endoscopic dacryocystorhinostomy (DCR) surgeries were performed. All the patients had been diagnosed as unilateral nasolacrimal duct obstruction and received CT-DCG examinations. According to the maximum transverse diameter of the lacrimal sac on CT-DCG, the patients were classified into three groups. Measurements were taken on CT-DCG parasagittal images. Results:The average distance from the sac superior fundus (SSF) to the MTA was 7.52mm±3.23mm, and it increased with the increase of the maximum transverse diameter of the sac among groups (p<0.01). The average distance from the common canaliculus (CC) to the MTA was 3.95mm±2.49mm. No significant difference among the groups (p=0.11). The average distance from the CC to the SSF was 3.41mm±1.31mm, and it increased with the increase of the sac transverse diameter among groups (p<0.01).Conclusions: The lacrimal sac can be accurately located on the lateral nasal wall by the reference position of the MTA on CT-DCG images. The distance of the SSF to the MTA and the SSF to the CC is influenced by the lacrimal sac size. The relative position of the CC to the MTA is relatively stable on CT-DCG images, which make it possible to locate the lacrimal sac of different sizes and the corresponding nasal mucosa incision design in endoscopic DCR.
Os caminhos entre o planejamento e as ações concretas frente aos resíduos sólidos em unidades de conservação: o caso da APA de Macaé de Cima, Rio de Janeiro, Brasil
Authors: Boy Walison , Nunes Maria Fernanda Santos Quintela da Costa
Published: June 2022

Os resíduos sólidos são um tema amplamente importante dentro das ações de gestão ambiental e devem ser priorizados no gerenciamento das unidades de conservação. O objetivo desse trabalho foi analisar como essa temática vem sendo desenvolvida na Área de Proteção Ambiental de Macaé de Cima (APAMC). Para isso, foi realizada uma análise de seu plano de manejo, a fim de identificar como esse tema foi trabalhado na proposta de gestão ambiental da unidade de conservação. Os resultados obtidos demonstram que as ações previstas não foram implementadas, numa clara omissão do tema por parte do poder público municipal, da empresa responsável pela coleta de resíduos e da administração da área de proteção ambiental. Com isso, uma nova etapa metodológica foi constituída na realização de pesquisas de iniciativas sustentáveis, encontradas no território da APAMC. Dois projetos, realizados pela sociedade civil organizada, destacam-se nesse contexto, através da reutilização de resíduos provenientes das confecções e da reciclagem. Essas iniciativas devem ser valorizadas e fomentadas pelo poder público e pela gestão da APAMC, visto que, o gerenciamento dos resíduos sólidos apresenta base na legislação brasileira (Plano Nacional de Resíduos Sólidos) e no plano de manejo da unidade de conservação. Além disso, o reaproveitamento desses materiais e a reciclagem dos resíduos pode ser uma alternativa na geração de renda para as famílias locais, como para mulheres artesãs.
Avaliação do licenciamento ambiental simplificado declaratório para atividades de baixo potencial poluidor no Estado de Pernambuco, Brasil
Authors: Oliveira Roberval da Silva , Marques Érika Alves Tavares , Brandão Sofia Suely Ferreira , Lyra Marília Regina Castro , Sobral Maria do Carmo Martins , Carvalho Renata Maria Caminha Mendes de Oliveira
Published: June 2022

O licenciamento ambiental o qual é tido como um dos principais instrumentos de proteção ambiental. O presente estudo buscou analisar o processo de implementação do licenciamento ambiental simplificado eletrônico adotado pela Agência Estadual de Meio Ambiente (CPRH), para atividades de baixo potencial poluidor levantando suas dificuldades e vantagens. Por meio do levantamento de dados primários e secundários foi feita a caracterização do licenciamento simplificado declaratório no Estado de Pernambuco e nos demais estados do Nordeste, formulando propostas de melhorias baseadas nos resultados obtidos. Foi verificado que após a implantação do sistema houve um aumento na demanda e outorga das licenças, mas também houve muitas licenças canceladas devido ao não cumprimento de exigências documentais. Não existe padronização do licenciamento simplificado, podendo variar substancialmente dentro dos próprios estados identificaram vários problemas que afetam negativamente o licenciamento.
Construções sustentáveis: uma oportunidade de aplicação nas obras do Instituto Federal do Amazonas
Authors: Monteiro Jeanni Alves Nunes , Conceição Roberta Dalvo Pereira da
Published: June 2022

Uma definição de sustentabilidade é ser ambientalmente correta, economicamente viável e socialmente justa. Nas obras públicas, há esforços para obtenção de construções sustentáveis, capazes de proporcionar benefícios como conforto, funcionalidade, satisfação e qualidade de vida, com menor impacto ambiental. Este artigo tem como objetivo, oportunizar a aplicação de construção sustentável nas obras do Instituto Federal do Amazonas (IFAM). A pesquisa teve enfoque qualitativo, com delineamento de pesquisa exploratória, descritiva e explicativa, caracterizada como estudo de caso. Foram analisadas as dimensões de sustentabilidade em duas obras do IFAM, o Bloco de Sala de Aula de Parintins e a Cozinha Experimental de São Gabriel da Cachoeira, no período de 2013 a 2018. O principal resultado da pesquisa é o desequilíbrio nas dimensões da sustentabilidade. Em ambas houve predomínio do eixo social, poucos de caráter ambiental e a principal finalidade econômica que é a entrega da obra, não foi atendida. No entanto, estas obras trazem uma reflexão acerca daelaboração dos projetos básicos alinhados à realidade local, uso de tecnologiasmais sustentáveis, na fiscalização e manutenção das obras públicas, diante de recursos públicos limitados.
Variabilidade climática e sua influência na produção da mamona Ricinus communis L. na Bahia
Authors: Sauceda Mayra Suyapa , Paludo Juliana Terezinha Sasso , Richardi Mayco Mascarello , Costa Ana Claudia da , Arruda Rafael Vinícius de
Published: June 2022

Objetivou-se com este trabalho estudar a relação dos fenômenos El Niño e La Niña, sua implicância no regime e volume da precipitação e na temperatura, e seu efeito na produção da mamona. Assim foram revisadas séries interanuais de dados de precipitação, temperatura e produção da mamona, aplicando-se a técnica de interpolação Krigagem ordinária para os dados produtivos e climáticos para o período de 2008 a 2019, em sete mesorregiões (46 cidades) do Estado da Bahia, tendo como hipótese de que essas variáveis definem a produtividade desta cultura, identificando as relações através de regressões entre chuva, temperatura e produção. No estudo foi possível perceber que estes fenômenos influenciam sobre a precipitação, provocando anomalias em todos os seus episódios. No El Niño, a demanda evaporativa da Bahia é maior e a precipitação menor, atingindo diretamente nos rendimentos que diminuiriam entre 1,8% e 76%, este resultado evidencia que, quanto maior a precipitação e temperatura, há um incremento e redução de produção, respectivamente. Os fenômenos meteorológicos afetam a dinâmica climática, ocasionando mudanças significativas no regime das chuvas máximas diárias, podendo aumentar ou diminuir o volume de precipitação em períodos do El Niño e La Niña, respectivamente. A precipitação e a temperatura influenciaram no desempenho da produção de mamona.
ICMS Ecológico: compensação e incentivo à proteção ambiental no Município de Tangará da Serra, Mato Grosso, Brasil
Authors: Silva Juraci do Espirito Santo , Servilha Graziele Oliveira Aragão , Santos Josiane Silva Costa dos , Morais Márcio Íris de , Nunes Edineia Souza , Oliveira Flávio Amaral
Published: June 2022

A pesquisa apresenta os benefícios gerados ao município de Tangará da Serra-MT com o recebimento do ICMS Ecológico, com vista a demonstrar o processo de repasse do ICMS Ecológico e analisar as ações públicas executadas. Trata-se de um estudo com abordagem quali-quantitativa, procedimentos estudo de caso e documental. Foram realizadas pesquisas documentais para conhecer as políticas que regulamentam o incentivo do ICMS Ecológico e os valores arrecadados. Além de entrevistas semiestruturadas, com o Secretário Municipal de Meio Ambiente e o Contador do Município de Tangará da Serra-MT. Os resultados evidenciaram que o município dispõe de um código ambiental, a Lei Complementar no. 149/2010, para destinar os recursos advindos do ICMSe. Mesmo não havendo uma disposição constitucional da vinculação do ICMSe, em benefício ao meio ambiente, o município prioriza a manutenção e conservação de áreas urbanas ambientais. O estudo comprovou que as áreas de conservação são geradoras de receitas para o município, além de ser um incentivo fiscal para criação e manutenção de unidades de conservação. Evidencia-se que quanto melhor a qualidade da gestão ambiental municipal maior o índice de participação no montante do ICMS, tornando ainda maior a quantidade de recursos financeiros a ser recebidos ao município.
Comparative Study on the Mechanical Properties of Weft Knitted and Warp Fabric Reinforced Composites
Authors: Getu TEMESGEN Alhayat , Sahu Omprakash
Published: June 2022

Knitted fabric composites occupy a special interest in the field of engineering and materials science because of their easy to form complex component and high impact energy absorption. Mechanical tests were carried out in the course, wale and slanting directions of the knitted fabric reinforced composites. The stress-strain curves and failure modes of warp and weft knitted fabrics were investigated and compared. The test results revealed from the composite structure fabricated from warp knitted fabric shown better mechanical properties than weft knitted fabric because of the warp knitted fabric distinct by the process of overlap between the stitches that gave better resistance.
TAGORE MEDICAL COLLEGE AND HOSPITAL CHENNAI-600 127 DEPARTMENT OF COMMUNITY MEDICINE COVID 19 VACCINE HESITANCY IN PATIENTS WITH COMORBIDITY: A HOSPITAL-BASED CROSS-SECTIONAL STUDY
Authors:   Professor and Head-Department of Community Medicine, Research Co-Ordinator-Central Research Lab, Tagore Medical College and Hospital, Chennai., T. Sucharitha Sree , Kavitha V. ,   Postgraduate, Department of Community Medicine, Tagore Medical College and Hospital, Chennai.
Published: June 2022

Background and aim: A vaccine advisory group to WHO identified complacency, inconvenience in accessing vaccines, and lack of confidence as key reasons underlying hesitancy. Vaccine hesitancy is one of the ten threats to global health in 2019. Hence, the present study was aimed to find out the factors associated with vaccine hesitancy among patients with comorbidities. Material and methods: A Hospital-based cross-sectional study was conducted among 372 patients with comorbiditieswho attended Tagore medical and Dental College and Hospital, Rathinamangalam, Chennai from June 2020 to August 2021 and were willing to participate in the study. A semi-structured interview schedule was used to obtain information on the socio-demographic profile, behavioral risk factors, and covid 19 vaccine details from the study participants. Data were analyzed using SPSS version 21.0. Results: Hypertension was the most prevalent (30%) co-morbidity among the study participants followed by Diabetes (27%).In the present study identified reasons for vaccine hesitancy, there was a statistically significant association with the age group, planning to take it soon, fear of adverse reactions of the comorbidities, not interested/not willing, need to take after specialistconsultation, health issues, and need to discuss with family members.Binary logistic regression was used to determine the association between vaccine hesitancy and possible factors.The odds of vaccine hesitancy among participants aged more than 60 years were 8 times(adjusted OR=8.044, CI: 1.92â€“33.1) higher than those aged 18 to 24 years. The odds of vaccine hesitancy among participants who had fear of adverse reactions attributed by the participant was 3 times (adjusted OR=2.824, CI: 1.10â€“7.25) higher than those without fear of adverse reactions.And the odds of vaccine hesitancy for participants who had a need to take after specialist consultation was 6 times (adjusted OR =5.935, CI: 1.52â€“23.1) higher than those who had after specialist consultation. Conclusion:This study concluded that the majority (23.6%) of the study participants mentioned that they were planning to take the vaccine in the future as the reason for delay followed by fear of adverse reactions attributed by comorbidities (21.2%) and health issues (18.55%).
PRIMARYOVARIANCARCINOID : A CASE REPORT AND REVIEW OF LITERATURE
Authors:   Department of Gynecology and Obstetric CHU Mohammed VI of Marrakesh, Morcco., S. Bahi , K. Dorkami ,   Department of Gynecology and Obstetric CHU Mohammed VI of Marrakesh, Morcco., H. Asmouki ,   Department of Gynecology and Obstetric CHU Mohammed VI of Marrakesh, Morcco., Benkaddour Y. Ait ,   Department of Gynecology and Obstetric CHU Mohammed VI of Marrakesh, Morcco., K. Harou ,   Department of Gynecology and Obstetric CHU Mohammed VI of Marrakesh, Morcco., A. Aboulfalah ,   Department of Gynecology and Obstetric CHU Mohammed VI of Marrakesh, Morcco., A. Soummani ,   Department of Gynecology and Obstetric CHU Mohammed VI of Marrakesh, Morcco.
Published: June 2022

Carcinoidtumors are rare, slow-growingneoplasmsthat arise from the neuroendocrine cells. However, carcinoidtumors of the ovaries are uncommon ,especiallyprimaryovariancarcinoidtumors, whichformapproximately 0.3% of all carcinoidtumors . Wepresenthere a rare case of a 51 yearsoldpatientwhoinitiallywaspresented for an ovarianteratoma and whoseanatomo-pathologicalstudyshowedthatwasa rare case of primary mixed insular and trabecularcarcinoidtumor of the ovary. The complement of the therapeutic management in this case wasdoneafteramultidisciplinary consultation meeting.
IMAGING IN DENTAL IMPLANTS
Authors: Raghavan Rohit , P.A Shajahan , Justin George
Published: June 2022

Dental implants have gained a lot of popularity among patients as a viable option for tooth replacement. It has recently become a standard treatment plan in many dental practices, and proper treatment planning is required to ensure a satisfactory outcome. As a result, radiography is an indispensable tool in providing information to clinicians so that an appropriate diagnosis and treatment strategy may be devised. Since the emergence of advanced imaging techniques, determining an appropriate implant imaging modality has become a challenge, and many of these modalities are being used for implant imaging. When it comes to imaging, the technique should take into account not only the anatomy but also the dimensional accuracy. As a result, all of the associated advantages and drawbacks should be considered while deciding on the type of imaging modalities.
REDUCING ATMOSPHERIC TURBULENCE IN IMAGES CAPTURED THROUGH CCTV IN WAR FIELD AREA
Authors:   Department of Computer Science and Engineering Chaitanya Bharathi Institute of Technology., Padhy Isha
Published: June 2022

Atmospheric turbulence caused by chaotic changes in air pressure and velocity will deter Charge Coupled Devices from getting a useful image which limits the capabilities of a surveillance system. The turbulent nature of the atmosphere poses a great problem in many situations. One such area is the Military. With rising conflicts around the world, security through surveillance and reconnaissance has increased. In such a situation, videos or images captured through long range observation systems in sensitive areas across the world need to be clear and without errors. Atmospheric turbulence is mainly caused by Refractive Index variation. This variation can be across space as well as time. Though refractive index of the atmosphere is a major factor, there are other factors like â€“ temperature, wind, pressure and humidity. The major goal of this paper is to reconstruct/repair the video/image obtained from the surveillance systems where the video/images are affected by turbulence. In this regard, we have focussed on the following aspects they are(a) Correcting the pixels and (b) Differentiating between static and dynamic objects.To achieve these objectives various solutions have been proposed based on both- mathematical and registration techniques. The registration techniques need some time during which many trial images/videos are taken in-order to construct a proper image. However, mathematical techniques involve performing complex operations in-order to achieve the correct value of the pixel. Our paper considersthe minimization of total variation in order to reduce the turbulence. It addresses the problem of turbulence in both, normal videos and thermal imaging.
BILATERAL CONGENITAL PTOSIS WITH CONGENITAL FIBROSIS OF EXTRAOCULAR MUSCLES (CFEOM) IN MONOZYGOTIC TWINS
Authors:   Department of Ophthalmology Santhiram Medical College and General Hospital, Nandyal â€“ 518501, Kurnool , Andhra Pradesh, India., Aneesha Priya B. , Anusha T. ,   Katuri Medical College, Guntur, Andhra Pradesh, India.
Published: June 2022

Cases of congenital ptosis are rare, that too occurring in twins. We are presenting a case of mono zygotic twins with bilateral ptosis with congenital fibrosis of extraocular muscles (CFEOM). A 5-year-old boy child and his twin brother who are monozygotic twins presented with bilateral ptosis. Both children had been diagnosed as having congenital fibrosis of extraocular muscles (CFEOM). Parents have refused surgical intervention for the extraocular muscle weakness. They were advised, if the twins complained of any visual abnormality, they should be brought to the ophthalmologists for further assessment.
THE PSYCHOLOGICAL AND ACADEMIC IMPACT OF COVID-19 AMONG STUDENTS OF COLLEGE OF MEDICINE IN SAUDI ARABIA 2020-2021
Authors:   MBBS, MD Community Medicine., Almutairi Afnan , Almutairi Abaad ,   MBBS, MD Community Medicine., Alrashedi Afrah ,   MBBS, MD Community Medicine., Almutairi May ,   MBBS, MD Community Medicine., Hakim Huda ,   MBBS, MD Community Medicine.
Published: June 2022

Background: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an emerging infection causing a widely spread pandemic of Coronavirus disease 2019 (COVID-19). The continuous spread of COVID-19, strict isolation measure, delays in starting colleges, attending offline classes, facing challenges to conduct high school grades for medical students across the country is expected to influence the psychological health and academic yielding of the students of colleges of medicine in Saudi Arabia. Objectives: This study aims to assess the psychological and academic impact of COVID-19 among the students of colleges of medicine in Saudi Arabia. Methodology: This cross-sectional study conducted from October 2020-March 2021 in which a survey conducted among medical students from 10 colleges of medicine in Saudi Arabia. An online questionnaire was conducted using social media platforms, including WhatsApp and Twitter, as well as email. The survey requested demographic and socioeconomic information, in addition to 4-point Likert Scale to assess the psychological and academic impact. Results: There were 661 responses in total. Most of the participants were female 51% (n=332), from Majmaah University 20.6% (n=134), and from the sixth year 26.3% (n=171). Majority of the participants were between the ages of 18 and 23 years 59.6% (n=388). The prevalence of COVID-19 among the participants was only 11.06% (n=72). During the height of the pandemic, 39.6% of the participants (n=258) stated that their GPA had risen. The extent of psychological distress was calculated using a 4-point Likert Scale, and the majority of the students (n=328) had moderate psychological distress. Similarly, most of the students had moderate academic impact 34.87% (n=227) due to COVID-19. There were a significant association between the degree of psychological distress and gender with male students reporting more mild 7.2% and moderate distress 23% while female students reported more moderately severe 20.1% and the severe distress 4.3%. In addition, there were an association between the level of stress and the academic performance. Conclusion: The result suggest that the COVID-19 has a moderate psychological distress and also moderate academic impact among students of colleges of medicine in Saudi Arabia.