bluuebunny/crossref_metadata_2025 huggingface dataset:
Attention-deficit/hyperactive-impulsive disorder symptoms among grade 1 students with reading disorder in Thailand
Authors: Sarisuta Patcharapun , Chunsuwan Issarapa , Hansakunachai Tippawan , Sritipsukho Paskorn
Published: October 2023

Background: Reading disorder is the most common comorbid condition with attention-deficit/hyperactive-impulsive disorder (ADHD) in school-aged children.Purpose: This study compared symptoms of ADHD among children in grade 1 at risk of reading disorder with children not at risk.Methods: This cross-sectional study included 703 students in grade 1 aged 6–8 years from 8 schools in Pathumthani Province, Thailand, in 2019. Reading disorder was assessed using tools developed by Vibulpatanavong and Evans for Thai teachers, whereas the Thai parent and teacher versions of the Swanson, Nolan, and Pelham IV Rating Scale (SNAP-IV) was used to evaluate ADHD symptoms. Demographic data were collected from parents using a self-reported questionnaire.Results: Among the 703 students with almost equal number of male (n=350) and female (n=353), and the average age of 6.56±0.57 years, 95 (13.51%) were classified (significantly male) at risk of reading disorder. The mean SNAP-IV scores of children with reading disorder reported by parents and teachers (20.23±10.95 and 20.75±15.08, respectively) were significantly higher than those of neurotypical children (16.04 ±8.59 and 9.00±10.14, respectively, P<0.05). Of the 95 students with reading disorder reported by parents and teachers, 29 (30.53%) and 20 (21.05%) respectively, were defined as having ADHD according to the standard cutoff SNAP-IV scores, which were significantly higher than 608 neurotypical students at 108 (17.76%) and 20 (5.59%) (P<0.05). The odds ratios of children with reading disorder having ADHD symptoms according to teacher reports were 3.32 (95% confidence interval [CI], 1.14–9.67; P<0.05), 3.75 (95% CI, 1.60–8.79; P<0.05), and 4.41 (95% CI, 1.20–16.15; P<0.05) for inattentive, hyperactive, and combined presentations, respectively.Conclusion: Grade 1 students with reading disorder had a significantly higher prevalence of ADHD symptoms than neurotypical students. Therefore, children with reading disorders should undergo ADHD assessments and receive proactive intervention.
AİHM’İN ÇEVRE İÇTİHATLARININ İKLİM DEĞİŞİKLİĞİ DAVALARINA UYGULANABİLİRLİĞİ
Authors: ALÇIK ENGÜRÜLÜ Merve
Published: October 2023

Çevre hakkını ayrıca ve açıkça düzenlemeyen Avrupa İnsan Hakları Sözleşmesinin (Sözleşme veya AİHS) denetim mekanizması olan Avrupa İnsan Hakları Mahkemesinin (AİHM) önüne çevre ile ilgili uyuşmazlıklar sıklıkla gelmektedir. Mahkemenin bugüne kadar çevresel meselelerle ilgili vermiş olduğu kararlar özellikle yaşam hakkı, özel ve aile hayatına saygı hakkı ile ilişkilendirilmektedir. Ayrıca Mahkemenin yargı yetkisine dair içtihatları bulunmaktaysa da sınır aşan çevresel zararlara dair yargı yetkisine ilişkin henüz verilmiş bir karar bulunmamaktadır. Yanı sıra son zamanlarda Mahkemeye iklim değişikliğinin zararlı etkileri sebebiyle Sözleşmedeki haklarının ihlal edildiğinden bahisle davalar da açılmaktadır. AİHM önüne gelen iklim değişikliği davaları yeni bir olgu olmasına karşılık henüz bu konuda Mahkeme tarafından verilmiş bir karar bulunmamaktadır.

İklim değişikliği davaları, iklim değişikliğinin zamana yayılan kümülatif etkileri sebebiyle, zarar riskinin ve mağduriyetin kanıtlanması; sınır aşan çevresel zararların meydana gelmesiyle devletlerin yargı yetkisinin belirlenmesi açısından zorluklar taşımaktadır. Bu makale mahkemenin daha önceden verdiği çevre içtihatlarının derdest olan iklim değişikliği davalarında uygulanabilirliğini özellikle sınır aşan çevresel zararlar karşısında mahkemenin yargı yetkisini nasıl belirleyeceği, başvurucuların mağdur statüsünü nasıl değerlendireceği ve yaşam hakkı ile özel ve aile hayatının korunması hakkının ihlal edilip edilmediğini inceleme yöntemi açısından ele almaktadır.
‘Inner world’ of luminal HER 2-negative metastatic breast cancer: Efficacy of ribociclib in different intrinsic subtypes
Authors: Kovalenko E. I. , Artamonova E. V.
Published: October 2023

The heterogeneity of breast cancer (BC), which determines various clinical scenarios of the disease, is still inaccessible to our understanding. Heterogeneity is based primarily on intrinsic subtypes of breast cancer, determined using genomic tests. Currently, four intrinsic subtypes are generally recognized: luminal A and B, HER-enriched (HER2-E) and basal-like. HER2-E subtype in luminal HER-negative (ER+HER–) breast cancer accounts for 11–22 per cent of cases. The efficacy of a combination of hormone therapy (HT) and the CDK4/6 inhibitor ribociclib in the HER2-E subtype was evaluated in a large exploratory analysis of MONALEESA-2, -3, and -7 trials. The gain in progression-free survival (PFS) and overall survival (OS) from the addition of ribociclib to HT was observed in all intrinsic subtypes, except for basal-like, and reached maximum in HER2-E subtype: Ribociclib increased the median PFS to 16.4 months from 5.5 months on HT (HR = 0.389; p < 0.0001) and median OS to 40.3 months from 29.4 months (HR = 0.600; p = 0.0180). The significant frequency of occurrence of the HER2-E subtype in ER+HER-BC, the low efficiency of monoHT in this subtype is another argument in favor of prescribing combination therapy in early lines. Information about the intrinsic subtype not only brings us closer to understanding tumor heterogeneity, but may also become a significant factor in determining treatment tactics in the future.
Multiple primary synchronous malignant skin neoplasms (case report and literature review)
Authors: Kukosh M. Yu. , Ronzin A. V. , Ter-Ovanesov M. D. , Avdalyan A. M. , Sarkisyan K. D.
Published: October 2023

The non-melanoma skin cancer is a leader among malignant tumours over last decades. Also, the incidence of multiple primary malignant neoplasms is increasing. We reported the case of a 68-year-old woman with locally advanced multiple primary synchronous malignant skin neoplasms (basal cell carcinoma and sarcomatoid carcinoma of skin) who was successfully treated. Thanks to individualized multimodal treatment, the basis of which is radical surgical intervention, careful follow-up was possible to achieve a complete cure of the patient with a good cosmetic and functional result. Our case report represents the need to increase the level of oncological alertness among primary care specialists and conduct educational work among the population in order to early diagnose tumors.
Management of arterial hypertension during therapy with antiangiogenic drugs in metastatic renal cell carcinoma
Authors: Kozyavin N. A. , Mureyko E. A. , Nikiforov V. S.
Published: October 2023

The use of antiangiogenic drugs in a single mode or in combination with immunotherapy in disseminated renal cell carcinoma has made it possible to achieve significant results in the therapy of the metastatic process. The flip side of effective therapy is the development of adverse events. An increase in blood pressure is one of the most frequent complications of antiangiogenic drug therapy with a frequency of up to 80 %.
Optogenetics Sheds Light on Brown and Beige Adipocytes
Authors: Brown Aaron Clifford
Published: October 2023

Excessive food intake leads to lipid accumulation in white adipose tissue, triggering inflammation, cellular stress, insulin resistance, and metabolic syndrome. In contrast, the dynamic energy expenditure and heat generation of brown and beige adipose tissue, driven by specialized mitochondria, render it an appealing candidate for therapeutic strategies aimed at addressing metabolic disorders. This review examines the therapeutic potential of brown and beige adipocytes for obesity and metabolic disorders, focusing on recent studies that employ optogenetics for thermogenesis control in these cells. The findings delve into the mechanisms underlying UCP1-dependent and UCP1-independent thermogenesis and how optogenetic approaches can be used to precisely modulate energy expenditure and induce thermogenesis. The convergence of adipocyte biology and optogenetics presents an exciting frontier in combating metabolic disorders and advancing our understanding of cellular regulation and energy balance.
Trombastenia de Glanzmann: Manejo multidisciplinario" Reporte de un Caso
Authors: Rivas Gianmarco , Cornejo José L. , Peñaloza Saúl J. , Guerrero Bruno R. , Javier Rosario , Vásquez Carol
Published: October 2023

El manejo odontológico del paciente con trombastenia de Glanzmann es complejo. Esta enfermedad se caracteriza por una disfunción en la agregación plaquetaria incrementando el riesgo hemorrágico durante una intervención quirúrgica. En el presente reporte de caso se realizó la administración de un fármaco de factor VII recombinante activado (rFVIIa) a una paciente de sexo femenino, lo que permitió controlar los episodios hemorrágicos producidos durante el tratamiento odontológico, esto en base a un enfoque multidisciplinario del servicio de hematología y el servicio de cirugía buco maxilofacial del Hospital Nacional Guillermo Almenara Irigoyen.
Tratamiento no quirúrgico de la gonartrosis
Authors: Picado-Brenes Daniel , Gutiérrez-Méndez Carolina María , Hernández-Bonilla Juan Alberto , Fernández-Durán Brian , Gómez-Rizo Vilma , Ajún-Ulate Fiorella , Vividea-García Bryann , Vázquez-Peña Abigail
Published: October 2023

La gonartrosis es una enfermedad degenerativa cada vez más común en la sociedad moderna, relacionada directamente con la edad avanzada y la obesidad. Aunque su fisiopatología no está completamente definida, diversos estudios han demostrado que cambios en el estilo de vida, como el ejercicio regular y el mantenimiento de un peso saludable, pueden mejorar los síntomas y frenar el progreso de la enfermedad. En este artículo de revisión se exploran las diferentes opciones de tratamiento no quirúrgico para la gonartrosis, destacando que los AINES tópicos y orales son los más respaldados por evidencia a corto y largo plazo. Los opioides, debido a sus riesgos y escasos beneficios a largo plazo, están perdiendo protagonismo en el abordaje de esta enfermedad. Además, se ha demostrado que el acetaminofén es ineficaz en el tratamiento de la gonartrosis. Por otro lado, se están investigando nuevas técnicas, como la inyección de sustancias intraarticulares, que podrían ofrecer opciones terapéuticas adicionales. En definitiva, se espera que se produzcan nuevos descubrimientos y avances en el tratamiento de esta patología en el futuro.
Conducta suicida: Datos y propuestas en población peruana
Authors: Perales-Cabrera Alberto , Castro-Baca Manuel , Matos-Retamozo Luis , Vásquez-Gómez Freddy , Sjogren Maria H.
Published: October 2023

Prevenir un suicidio es, actualmente, prioridad en Salud Pública ya que es la principal razón de muerte violenta en elmundo. Globalmente, cada año, cerca de un millón de personas mueren por suicidio, aunque hay un sub-registro significativo(1). La epidemiologia y tasa de suicidios es diferente en el mundo; así, se registra mayor número de suicidios en Europadel Este, comparado a América Latina. Igualmente, el género masculino registra mayor cantidad de suicidios consumados,aunque el sexo femenino tiene un número mayor de intentos suicidas. Vale mencionar que, frecuentemente, se observaintentos previos antes de consumarlo. Tal conducta debe alertarnos pues ofrece esperanza que una intervención apropiada y pronta puede reducir el número de víctimas.
Características metabólicas basales de los diabéticos de nivel del mar y de la altura
Authors: Garmendia-Lorena Fausto , Pando-Alvarez Rosa
Published: October 2023

Objetivo: Se efectuó un estudio descriptivo, analítico, transversal con grupo control, en el que se comparó el metabolismointermediario basal de pacientes con Diabetes Mellitus tipo 2 (DM2), tanto de nivel del mar (NM) como de altura (ALT). Metodología: Se ha estudiado a 33 DM2 de nivel del mar (Lima, 150 m sobre el nivel del mar) y 28 DM2 de altura (Cusco, 3395 msnm), de ambos géneros, de 40 a 70 años de edad. Se tomaron medidas antropométricas y en condiciones basales se efectuaron determinaciones glucosa (G), triglicéridos (Tg), insulina (I), ácidos grasos no esteroideos (AGNE), colesterol total (CT), cHDL, triglicéridos (Tg), cVLDL, cLDL, cNoHDL; se calculó el colesterol VLDL, LDL, NoHDL, hemoglobina glicosilada (HbA1c) y el coeficiente HOMA. Los cálculos estadísticos mediante el programa SPSS v. 23. Resultados: Los DM2 de altura tuvieron valores significativamente más altos de peso, talla, HDL, Tg y AGNE. Discusión y Conclusiones: Los pacientes con DM2, expuestos a una altura de 3395 metros sobre el nivel del mar, mostraron pocas diferencias metabólicas en comparación a los pacientes DM2 de nivel del mar.
Advertencia sobre los edulcorantes sintéticos
Authors: Calderón Velasco Rolando
Published: October 2023

La excesiva ingestión de carbohidratos simples (azúcares) amenaza la salud y provoca enfermedades metabólicas.
Innovative mechanisms of formation of unconditional basic income
Authors:   SESE “The Academy of Financial Management”, LEVIN Volodymyr
Published: October 2023

The article is devoted to the disclosure of the features of introducing unconditional basic income under the conditions of the spread of digitization and automation of all spheres of human activity. UBI can play a critical role in poverty alleviation by extending social protection to informal workers, promoting gender equality, stimulating the macro-economy during crises and redistributing dividends from natural wealth. It outlines a situation where the UBI appears to be a particularly appropriate approach to redistribute the gains from automation and globalization by creating an effective and transparent barrier against global instability and systemic risks, creating positive incentives and avoiding recurring risks of impoverishment. Attention is paid to the specifics of the relationship between IT companies and their employees, thanks to which the latter get the opportunity to purchase company shares under special conditions and at discounted prices, and a comparison of this approach with the position of Kuwaiti citizens in the context of the UBI is made. The role of the leading states, in particular the G7, which, with the help of special tax methods, are trying to regulate the activities of multinational corporations, while striving to ensure the so-called digital transition, is emphasized. With regard to Ukraine, the importance of balanced development of all sectors of the economy and ensuring economic growth after the abolition of benefits for the IT industry was emphasized. It is concluded that the implementation of stock option programs or benefits, similar to those that exist in Kuwait for citizens of the state, will help to overcome poverty, conserve resources and reduce the impact of human activities on the natural environment, and therefore ensure the sustainable development of the country.
Methodological approaches to establishing the borders of the forest-park green belt
Authors:   Tomsk State University of Architecture and Building, Gubanischeva M. A. ,   Tomskelectrosetproject LLC, Avrunev E. I. ,   Siberian State University of Geosystems and Technologies, Gamova O. V. ,   Tomsk State University of Architecture and Building; Geomix LLC, Kalenitsky A. I. ,   Siberian State University of Geosystems and Technologies, Khoroshilov V. S. ,   Siberian State University of Geosystems and Technologies
Published: October 2023

The article discusses methodological approaches to the problems of performing work in relation to the forest-park green belt of territorial entities and the procedure for establishing its boundaries. The analysis of the legal support of the work is carried out, the most problematic aspects are formulated and possible ways of their solution are given. It has been established that the existing problems are based on the inconsistency of the relevant regulatory documents and the lack of unified methodological and technological approaches to the implementation of such work. To eliminate the established negative aspects that significantly affect the quality of the work performed, a technological scheme is proposed. This scheme has successfully passed adaptation in the territorial formation of the Russian Federation. The result of the implementation was the entry into the Unified State Register of Real Estate of information on the formed boundaries of the forest-park zone of the city of Tomsk.
Register errors and their impact on cadastral system efficiency
Authors:   Siberian State University of Geosystems and Technologies, Klyushnichenko V. N. , Dubrovsky A. V. ,   Siberian State University of Geosystems and Technologies, Evsyukova I. N. ,   Siberian State University of Geosystems and Technologies
Published: October 2023

In the process of cadastre maintenance there appear errors of different kinds. Besides, there occur errors in data of previously registered land plots, which causes suspension of cadastral registration, thus, prolongs the cadastre and right registration terms. So, a submitter does not get on time the required document, which affirms their right for an object. In this case the tax collection is not carried out properly, which reduces the efficiency of the cadastral system. The article describes the problems occurring when register errors appear, gives recommendations for their correction in both judicial and non-judicial order. The article substantiates the negative impact of register errors on the rights of individuals and legal entities, who previously registered real estate. The article offers the recommendations for mitigating the impact of these errors on the rights of individuals and legal entities who own real estate.
Improving the reliability of acceleration measurements during vibration tests
Authors:   JSC ", Edvabnik V. G. ,   Research Institute ",   Octava", Kuznetsov M. M. ,   Siberian State University of Water Transport
Published: October 2023

The paper analyzes some causes of distortion of the set and measured vibration parameters during testing of equipment on an electrodynamic vibration stage. In particular, the influence of the joints of the mating surfaces on the vibration stand – a transition table and a transition table – a device for vibration is determined. An idealized model of the junction of two surfaces is proposed, which can be theoreti-cally described using the theory of generalized conductivity of heterogeneous structures. The joint is represented as a matrix of metal with inclusions of voids, represented as components of a mixture having infinite conductivity. A relation is derived showing that the elasticity model of the two metal surfaces joint is approximately 30 % less than that of a homogeneous metal. The obtained theoretical conclusions substantiate the recommendation to increase the rigidity of the mechanical system "vibration stand table - transition table – device for vibration tests" by introducing a thin (40...80 microns) polyethylene film into the joints. The fundamental reason for the difference in the measurement of the vibration acceleration magnitude at different control points is shown – the presence of a tipping moment in the mechanical system. Elimination of a methodological error during vibration tests is possible when controlling the vibration stand not by a real, but by a conditional control point. Recommendations on the choice of a conditional control point for the vibration stand during vibration tests of the equipment are given and justified.
Geodetic supply of alignment the reflecting surface’s shape of the main mirror of a radio telescope using laser trackers
Authors:   Saint Petersburg Mining University, Kuzin A. A. , Petrov V. V. ,   LLC Industrial Geodesy, Peftiev A. A. ,   LLC Industrial Geodesy
Published: October 2023

The article discusses the possibilities of coordinate-determining technology using high-precision geodetic instruments for alignment of reflecting surface shape of the radio telescope main mirror. It’s important for adjustment of reflecting surface shape and consequently performance of radio astronomy observations. The article provides general information about radio telescopes and consideres the existing classical geodesic and non-geodesic methods used in the process of solving the problem of shape alignment. The text describes the method of geodetic work on the form alignment using high-precision laser trackers. The methodology includes several stages from designing the geodetic control network and tracker location stations and processing and interpreting the measurement results. The conditions for performing high-precision measurements are given in the thesis. Mathematical processing of measurement results is performed in the Spatial Analyzer and based on coordinate systems transformation.
Mathematical modeling of the displacements dynamics of landslide slopes under the conditions of technogenic impacts
Authors:   Siberian State University of Geosystems and Technologies, Khoroshilov V. S. , Pavlovskaya O. G. ,   Siberian State University of Geosystems and Technologies, Kobeleva N. N. ,   Siberian State University of Geosystems and Technologies, Yambaev Kh. K. ,   Moscow State University of Geodesy and Cartography
Published: October 2023

The article discusses the features of mathematical modeling of the stress-strain state of landslide slopes to predict their movements. Regular control and monitoring of exogenous geological processes are important elements of a qualitative assessment of landslide events, including both the timely identification of areas with the greatest danger and the elimination of their consequences. The natural and technogenic features of the study area are considered. The previous results of the processing of geodetic observation data are presented, which are the basis for mathematical modeling of the stress-strain state of landslide slopes and for predicting their movements. Based on the Fourier transform, a spectral study of the vertical displacements of landslide signs was carried out and an analysis of the obtained spectrograms was made. Modeling of movements of landslide slopes subject to technogenic impacts (blasting and removal of a large amount of soil) is implemented on the basis of a forecast dynamic model. The model is presented in a recurrent form in the form of the first two conditional moment functions, which made it possible to predict the movements of controlled landslide slopes with a sufficiently high accuracy.
Hardware and software implementation of the infrastructure of the Unified Geoinformationcenter of forestry
Authors:   St. Petersburg State Forest Technical University named after S. M. Kirov, Vagizov M. R. , Zayats A. M. ,   St. Petersburg State Forest Technical University named after S. M. Kirov
Published: October 2023

The presented material is a continuation of the article on the concept of Unified Geoinformation Center (UGS) infrastructure, revealing the architecture of the information system model implementing the network-centric approach as the main aspect – the principle of interoperability. The network-centric approach in building the information system of UGS is embodied in the union of all objects of the sys-tem, both within and outside the perimeter in a single information space (network-centric environment), and interoperability is ensured by the proposed interaction technology based on the advanced message queuing protocol – AMQP, which provides for all objects of the network-centric environment the possibility of free mutual exchange of information, regardless of the functions they perform and their internal structure. On this basis, the scheme of the architecture of the information system of the unified geoinformation center of the forestry, with components both in its perimeter and outside it, is proposed.
Designing the transceiver part of a two-channel infrared lidar system
Authors:   V. E. Zuev Institute of Atmospheric Optics of Siberian Branch of the Russian Academy of Sciences, Sadovnikov S. A. , Yakovlev S. V. ,   V. E. Zuev Institute of Atmospheric Optics of Siberian Branch of the Russian Academy of Sciences, Kravtsova N. S. ,   V. E. Zuev Institute of Atmospheric Optics of Siberian Branch of the Russian Academy of Sciences, Gerasimova M. P. ,   V. E. Zuev Institute of Atmospheric Optics of Siberian Branch of the Russian Academy of Sciences
Published: October 2023

The study is aimed at determining the optimal parameters of the elements of a two-channel near-IR lidar system. One of the first stages in the design and development of li-dar systems that solve the problems of remote gas analysis of the atmosphere is the calculation of the overlap function. As part of the study, numerical simulation of the overlapping function of the lidar system was carried out for various configurations of the transceiver path. The simulation results showed that when using a Mersenne telescope with specified parameters in the receiving part of the lidar, it is preferable to focus the laser radiation at a distance from the transmitting path in order to obtain a complete overlap of the field of view of the telescope and the laser beam while minimizing the "dead" zone of the lidar operation. The results obtained will be further applied in the development of the design of a two-channel lidar system for measuring the concentrations of greenhouse gases in the atmosphere.
Development of a geodetic simulator in virtual reality mode
Authors:   Siberian State University of Geosystems and Technologies, Kirilov N. A.
Published: October 2023

The introduction of virtual reality technologies in the educational process in addition to educational and industrial practices will allow а student to gain more experience with geodetic instruments under different conditions. The aim of the research is to develop a geodetic simulator, which can facilitate the experience of future specialists and improve the quality of the educational process. The article presents the development of the main menu of the simulator, the creation of a demo room of geodetic instruments, as well as testing of the developed software product. The result of the research is the creation of a fully functioning simulator of work with geodetic equipment in virtual reality, which allows supplementing both the distance learning process of future geodesists and the full-time educational process. Being a universal tool, the simulator will be useful not only for training future specialists, but also will help specialists with work experience to refresh their knowledge and practice with geodetic equipment at different locations.
Determination of changes in the trajectory and orientation of unmanned aerial vehicles from overlapping images
Authors:   Southwest State University, Andronov V. G. , Chuev A. A. ,   Southwest State University
Published: October 2023

The article considers a method for determining abnormal changes in the trajectory and orientation of unmanned aerial vehicles in the conditions of loss of signals from satellites in the interests of improving the accuracy of navigation support for their exit to a given point of the horizontal flight route. The developed technique is based on the functional relationship of the difference in parallaxes of adjacent pairs of images obtained by the onboard camera of unmanned aerial vehicles during flight, with their deviations from the horizontal trajectory and changes in orientation. The obtained analytical relations allow for each corresponding point of a pair of images to form and solve a system of two nonlinear equations with five unknowns, which use deviations of unmanned aerial vehicles in altitude and direction of flight and their pitch, roll and yaw angles, approximate values of which are determined by the inertial navigation system. The procedures for the refinement of these parameters based on the math-ematical processing of the measurement results of the plane coordinates of the corresponding points by the method of least squares are presented. The proposed approach makes it possible to halve the minimum number of processed points and ensures the accuracy of determining the deviations of unmanned aerial vehicles from the horizontal trajectory and changes in its angular orientation, commensurate with the accuracy of satellite navigation.
Creation of a three-dimensional map of the Karazhyra coal deposit, contaminated with technogenic radionuclides for inventory purposes
Authors:   Siberian State University of Geosystems and Technologies, Issabekova K. S. , Ustavich G. A. ,   Siberian State University of Geosystems and Technologies, Kuderinov S. M. ,   Siberian State University of Geosystems and Technologies, Kuderinova N. A. ,   Siberian State University of Geosystems and Technologies
Published: October 2023

The closure of the Semipalatinsk nuclear test site (SNTS) and the introduction of its lands into the national economic circulation makes it possible to carry out various economic activities on its territory. Such activity also includes the development of the Karazhyra coal deposit located on its territory. During the nuclear tests, technogenic radionuclides contaminated the upper soil layer of this deposit, as well as groundwater. Currently, during overburden operations and subsequent coal mining, intensive dust formation occurs, which leads to secondary pollution by wind transfer of technogenic radionuclides, which leads to an expansion of the polluted area over the territory adjacent to the landfill. At the same time, the direction of transfer largely depends on the wind rose, which changes throughout the year. The transfer of radionuclides also occurs when contaminated coal is transported by road to Semey to industrial enterprises, as well as to the population of private houses. To ensure monitoring of the development of secondary pollution of this deposit and the territory adjacent to the landfill, it is necessary, in order to safely conduct economic activities, in particular cadastral activities, to display the level of pollution and the dynamics of its expansion on boundary plans. In this regard, consideration of this issue is relevant and timely. The article indicates the types of work that have an impact on the radiation situation of the environment, including on the lands adjacent to the Karazhyr coal mine. It has been established that the method of performing geodetic and cadastral work will be influenced by the level of territory contamination with technogenic radio nuclides. To display the level of pollution at different horizons, a method for creating a three-dimensional map of the deposit and a part of the territory adjacent to it is proposed.
Multi-factor approach to development of efficient land use methodology
Authors:   Saint Petersburg Mining University, Khaikin M. М. , Trushnikov V. E. ,   Saint Petersburg Mining University, Lenkovets O. M. ,   Saint Petersburg Mining University
Published: October 2023

Efficient land use is a key condition for sustainable development of the society. Its implementation involves the coordination of various resources in the economy, ecology, social sphere, technology, and law. The development of efficient land use methodology is based on the use of a multi-factor ap-proach covering tight interdisciplinary collaboration, which results in the search for an integral indicator that generally reflects the efficiency of land use; calculation of private indicators, whose values give a picture of the current state of land use in the relevant institutional environment. The article highlights the main unsolved land use issues in Russia. The authors emphasize the role of the state and the legal framework in the land regulation, a differentiated approach to the subjects, the specific features of the economic model ensuring the efficient land use.
Development of a software module for calculation of the environmental forming potential of the territory of the Tyumen region
Authors:   Industrial University of Tyumen, Chernykh E. G.
Published: October 2023

The author has developed a software package for the analysis of indicators of the spatial development of the territory of the region using the MapBasis programming language for the MapInfo GIS. As a topographical basis, a map of the Tyumen region was digitized, as well as maps of the subjects of the region, and the following thematic layers were created: the administrative division of the "big Tyumen region" into subjects of the Russian Federation, the administrative division of each subject into municipal districts, and the lands of settlements are shown and agricultural land for each subject of the Russian Federation, as well as layers of hydrography of the “big Tyumen region”. The created layers contain analyzed information and are used to build diagrams, as well as visual display of cartograms, visually showing the intensity of any indicator within the territory on the map.
Study of the accuracy of global geopotential models EGM2008, EIGEN-6C4, GECO, SGG-UGM-1, SGG-UGM-2, XGM2019 on the territory of the Russian Federation
Authors:   Siberian State University of Geosystems and Technologies, Kanushin V. F. , Goldobin D. N. ,   Siberian State University of Geosystems and Technologies, Kobeleva N. N. ,   Siberian State University of Geosystems and Technologies
Published: October 2023

The improvement of the gravimetric knowledge of the Russian Federation and the creation of new models of the Earth's gravitational field (EGF) in the form of spherical harmonics of the geopotential set the task of choosing the most suitable model based on the characteristics of the gravitational field on the territory of Russia. The satellite gravity missions CHAMP, GRACE and GOCE provide a homoge-neous and almost complete global coverage of information about the Earth's gravitational field. The paper presents the results of a study of the accuracy of modern high-degree global geopotential models for determining various characteristics of the Earth's gravitational field on the territory of the Russian Federation. The models EGM2008, EIGEN-6C4, GECO, SGG-UGM-1, SGG-UGM-2 and XGM2019 were used as the tested geopotential models. The results of the study are presented in the form of statistical parameters and histograms of the distribution of differences g between the gravity values obtained from ground-based gravimetric measurements and calculated from model data. The high-degree model EIGEN-6C4 has a smaller standard deviation ( = 5,24 mGal) compared to other geopotential models. Based on the distribution of differences, we can conclude that the EIGEN 6C4 model is the most suitable for the territory of the Russian Federation.
The method of transformation of three-dimensional positions of points between geocentric and reference coordinate systems for regional territories
Authors:   Siberian State University of Geosystems and Technologies, Shendrik N. K.
Published: October 2023

A technique was developed for converting three-dimensional positions of points for regional territories between geocentric and reference coordinate systems (RCS) by matching the Helmert parameters with the geoid height model for the reference coordinate system and the three-dimensional positions of points in both SC. The technique is based on replacing the quasigeoid height model to the EGM2008 geoid height model transformed for reference coordinate systems. For regional territories, the accuracy of determining the Helmert parameters and the accuracy of transformations of coordinates and heights of points at the level of accuracy of the positions of points in the general and reference coordinate systems is ensured. Examples of calculations of the agreed Helmert parameters with the transformed elevation model of the EGM2008 geoid between the reference coordinate system SK-95 and WGS-84, SK-42, GSK-2011 for the territory of the Novosibirsk region are given.
Complex organization of alluvial territories in St. Petersburg
Authors:   Saint-Petersburg State Agrarian University, Uvarova E. L. , Pavlova V. A. ,   Saint-Petersburg State Agrarian University
Published: October 2023

The features of the creation artificial land plots are indicated by legislation in the field of urban planning and cadastre in the Russian Federation at the present stage. However, in the Earth sciences there are no methodological provisions for the integrated organization of alluvial territories. Based on the legal activities and works of scientists on the designated research topic, the authors proposed an approach and a scheme for the integrated organization of alluvial territories. This scheme ensures the integration of urban planning, land management and cadastre institutions. According to the authors, the creation of artificial land plots on a water body should be based on an assessment of the rationality for creating such a plot using multicriteria analysis, which includes three groups of criteria: social, economic, environmental. In addition, the article tests the author's methodological approach to the integrated organization of alluvial territories in St. Petersburg. According to the results of testing, two projects ("New Coast", "Bay of Islands") were recognized as irrational. Thus, it is necessary to approve an integrated approach for the organization of alluvial territories.
Herbicide programs, cropping sequences, and tillage-types: a systems approach for managing Amaranthus palmeri in dicamba-resistant cotton
Authors: Vulchi Rohith , Nolte Scott , McGinty Joshua , McKnight Benjamin
Published: October 2023

Herbicide-resistant Amaranthus palmeri poses a significant threat to cotton production in the US. Tillage, cover crops, crop rotations, and dicamba-based herbicide programs can individually provide effective control of A. palmeri, but there is a lack of research evaluating the above tactics in a system for its long-term management. Field trials were conducted near College Station and Thrall, TX (2019–2021) to evaluate the efficacy of dicamba-based herbicide programs under multiple cropping sequences and tillage types in a systems approach for A. palmeri control in dicamba-resistant cotton. The experimental design used was a split–split plot design. The main plots were no-till cover cropping, strip tillage, and conventional tillage. The subplots were cotton:cotton:cotton (CCC) and cotton:sorghum:cotton (CSC) sequences for 3 years within each tillage type, and sub-subplots were a weedy check (WC), a weed-free check (WF), a low-input program without residual herbicides (LI), and a high-input program with residual herbicides (HI). Using HI under the CSC sequence was the only system that provided >90% control of A. palmeri for 3 years across all tillage types and locations. By 2021, A. palmeri densities in the CSC sequence at College Station (4,156 plants ha−1) and Thrall (4,006 plants ha−1) are significantly low compared to the CCC sequence (31,364 and 9,867 plants ha−1, respectively) when averaged across other factors. Similarly, A. palmeri densities in HI at College Station (9,867 plants ha−1) and Thrall (1,016 plants ha−1) are significantly low compared to LI (25,653 and 13,365 plants ha−1, respectively) when averaged across other factors. We also observed that the CSC sequence reduced A. palmeri seed bank by at least 40% compared to the CCC sequence at both College Station and Thrall when averaged across other factors. Over 3 years, we did not observe significant differences between LI and HI for cotton yields at College Station (1,715–3,636 kg ha−1) and Thrall (1,569−1,989 kg ha−1). However, rotating cotton with sorghum during 2020 improved cotton yields by 39% under no-till cover cropping in 2021 at Thrall. These results indicate that using dicamba-based herbicide programs with residual herbicides and implementing crop rotations can effectively manage A. palmeri in terms of seasonal control, densities, and seed bank buildup across tillage types and environments.
Detection of environmental nanoplastics via surface-enhanced Raman spectroscopy using high-density, ring-shaped nanogap arrays
Authors: Luo Sihai , Zhang Junjie , de Mello John C.
Published: October 2023

Micro- and nano-plastics (MNPs) are global contaminants of growing concern to the ecosystem and human health. In-the-field detection and identification of environmental micro- and nano-plastics (e-MNPs) is critical for monitoring the spread and effects of e-MNPs but is challenging due to the dearth of suitable analytical techniques, especially in the sub-micron size range. Here we show that thin gold films patterned with a dense, hexagonal array of ring-shaped nanogaps (RSNs) can be used as active substrates for the sensitive detection of micro- and nano-plastics by surface-enhanced Raman spectroscopy (SERS), requiring only small sample volumes and no significant sample preparation. By drop-casting 0.2-μL aqueous test samples onto the SERS substrates, 50-nm polystyrene (PS) nanoparticles could be determined via Raman spectroscopy at concentrations down to 1 μg/mL. The substrates were successfully applied to the detection and identification of ∼100-nm polypropylene e-MNPs in filtered drinking water and ∼100-nm polyethylene terephthalate (PET) e-MNPs in filtered wash-water from a freshly cleaned PET-based infant feeding bottle.
Challenging DESs and ILs in the valorization of food waste: a case study
Authors: Mero Angelica , Moody Nicholas R. , Husanu Elena , Mezzetta Andrea , D’Andrea Felicia , Pomelli Christian Silvio , Bernaert Nathalie , Paradisi Francesca , Guazzelli Lorenzo
Published: October 2023

In this study, the efficacy of two of the best performing green solvents for the fractionation of lignocellulosic biomass, cholinium arginate (ChArg) as biobased ionic liquid (Bio-IL) and ChCl:lactic acid (ChCl:LA, 1:10) as natural deep eutectic solvent (NADES), was investigated and compared in the pretreatment of an agri-food industry waste, apple fibers (90°C for 1 h). For the sake of comparison, 1-butyl-3-methylimidazolium acetate (BMIM OAc) as one of the best IL able to dissolve cellulose was also used. After the pretreatment, two fractions were obtained in each case. The results gathered through FTIR and TG analyses of the two materials and the subsequent DNS assay performed after enzymatic treatment led to identify ChArg as the best medium to delignify and remove waxes, present on the starting apple fibers, thus producing a material substantially enriched in cellulose (CRM). Conversely, ChCl:LA did not provide satisfactorily results using these mild conditions, while BMIM OAc showed intermediate performance probably on account of the reduced crystallinity of cellulose after the dissolution-regeneration process. To corroborate the obtained data, FTIR and TG analyses were also performed on the residues collected after the enzymatic hydrolysis. At the end of the pretreatment, ChArg was also quantitatively recovered without significant alterations.
Electron-hole asymmetry in the phase diagram of carrier-tuned CsV3Sb5
Authors: Capa Salinas Andrea N. , Ortiz Brenden R. , Bales Calvin , Frassineti Jonathan , Mitrović Vesna F. , Wilson Stephen D.
Published: October 2023

In this work, we study the effect of electron doping on the kagome superconductor CsV3Sb5. Single crystals and powders of CsV3Sb5−xTex are synthesized and characterized via magnetic susceptibility, nuclear quadrupole resonance, and x-ray diffraction measurements, where we observe a slight suppression of the charge density wave transition temperature and superconducting temperature with the introduction of electron dopants. In contrast to hole doping, both transitions survive relatively unperturbed up to the solubility limit of Te within the lattice. A comparison is presented between the electronic phase diagrams of electron- and hole-tuned CsV3Sb5.
Speaking of sepsis: semantics, syntax, and slang
Authors: Inglis Tim J. J.
Published: October 2023

Medical language is in a constant state of evolution. Its grammar and vocabulary are not fixed by rigid rules. The interdisciplinary field of sepsis has become a meeting point for new insights arising from advances in systems biology, epidemiology, mechanistic understandings of disease process and antimicrobial interventions. This convergence has gained from our recent experience of SARS-CoV-2 infection and COVID-19 and possibilities inferred from emerging information technology. Biomedical descriptors have diverged along disciplinary lines creating an unfortunate disconnect between clinical and laboratory-based terminology. The resulting confusion between clinically determined sepsis and laboratory verified bloodstream infection raises practical questions that affect daily operational processes in the ward, clinic and laboratory. There is an urgent need to understand how the clinical sepsis pathway and corresponding clinical laboratory workflow can be better aligned as a single coherent entity. There is also an implicit need to understand how this process should produce actionable information in a timely and orderly manner, and identify residual obselete terminology that has crept into common usage. A widely accepted sepsis epistemology, ontology and heuristic will help us improve our clinical management of sepsis.
A scoring system based on fusion genes to predict treatment outcomes of the non-acute promyelocytic leukemia pediatric acute myeloid leukemia
Authors: Weng Wenwen , Chen Yanfei , Wang Yuwen , Ying Peiting , Guo Xiaoping , Ruan Jinfei , Song Hua , Xu Weiqun , Zhang Jingying , Xu Xiaojun , Tang Yongmin
Published: October 2023

Background

Fusion genes are considered to be one of the major drivers behind cancer initiation and progression. Meanwhile, non-acute promyelocytic leukemia (APL) pediatric patients with acute myeloid leukemia (AML) in children had limited treatment efficacy. Hence, we developed and validated a simple clinical scoring system for predicting outcomes in non-APL pediatric patients with AML.

Method

A total of 184 non-APL pediatric patients with AML who were admitted to our hospital and an independent dataset (318 patients) from the TARGET database were included. Least absolute shrinkage and selection operation (LASSO) and Cox regression analysis were used to identify prognostic factors. Then, a nomogram score was developed to predict the 1, 3, and 5 years overall survival (OS) based on their clinical characteristics and fusion genes. The accuracy of the nomogram score was determined by calibration curves and receiver operating characteristic (ROC) curves. Additionally, an internal verification cohort was used to assess its applicability.

Results

Based on Cox and LASSO regression analyses, a nomogram score was constructed using clinical characteristics and OS-related fusion genes (CBFβ::MYH11, RUNX1::RUNX1T1, KMT2A::ELL, and KMT2A::MLLT10), yielded good calibration and concordance for predicting OS of non-APL pediatric patients with AML. Furthermore, patients with higher scores exhibited worse outcomes. The nomogram score also demonstrated good discrimination and calibration in the whole cohort and internal validation. Furthermore, artificial neural networks demonstrated that this nomogram score exhibits good predictive performance.

Conclusion

Our model based on the fusion gene is a prognostic biomarker for non-APL pediatric patients with AML. The nomogram score can provide personalized prognosis prediction, thereby benefiting clinical decision-making.