bluuebunny/crossref_metadata_2025 huggingface dataset:
Effects of polymorphisms in DGAT1 and LEP genes on milk traits in Holstein primiparous cows
Authors:   National Agricultural and Food Centre, Research Institute for Animal Production Nitra, Hlohovecká 2, 951 41 Lužianky, Slovak Republic, Tomka Ján
Published: August 2023

The genes encoding the diacylglycerol O-acyltransferase (DGAT1) and leptin (LEP) became a functional candidate genes for lactation traits in cows. Several studies associated single nucleotide polymorphisms (SNP) in these genes with fat and protein content in milk, fat and protein yield, milk yield and some reproductive traits. Three reported SNPs in these genes were investigated in our study (DGAT1-K232A, LEP-R25C, LEP-A80V). One hundred and sixty-three primiparous dairy cows from one farm were genotyped. The milk yield, fat and protein yield, fat and protein content and the age at first calving were recorded. The frequencies of alleles and genotypes were assessed. The effect of genotypes on milk traits and age at first calving were studied using linear models. The assumption of the different allele frequencies resulting from selection aimed at milk yield was proved in DGAT1 and LEP-A80V. The significant effect (P<0.01) of DGAT1 polymorphism was estimated only for the fat content. No significant effect of individual LEP polymorphism on milk trait or age at first calving was estimated. No significant effect of combination of LEP polymorphisms was estimated for those traits. The effect of DGAT1 on the age at first calving was indicated.
The effect of crude protein in the diet on the quantity and composition of milk in Alpine goats
Authors:   Sveučilište u Zagrebu, Agronomski fakultet, Zavod za mljekarstvo, Svetošimunska 25, 10000 Zagreb, Hrvatska, Bendelja Ljoljić Darija
Published: August 2023

The excess of protein and lack of energy in the diet of goats cause an excess of nitrogen compounds in the rumen with the release of ammonia and the increase of urea concentration in blood and milk, which adversely affects: production and processing properties of milk, environmental pollution and reproductive performance. The aim of the present study was to determine the effect of short-term (30 days) changes of meals in the view of different content of crude protein (CP) to: daily milk yield (DMY), the concentration of urea (U) and the ratio between fat and protein (F/P) in milk. Preliminary research was conducted on 72 Alpine goats, grouped into three groups (I, II, III), with 24 randomly selected goats. From kidding to weaning, goats were fed with the same meal (11 % CP), which was followed by period of short-term feeding with different amounts of CP in the meal (I -14 % low proportion, II - 16 % optimal proportion, III - 18 % high proportion). The increase of CP in portion for 4 %, 4 % and 6 % resulted in an increase of the DMY for: 1.29 L, 1.48 L and 1.91 L, and also the concentration of urea for 16, 26 and 30 mg/100 mL. The ratio of F/P decreased in I, II, and III group from 1.55 to 1.24; from 1.53 to 1.18 and from 1.39 to 1.12. Optimizing nutrition in terms of a more rational protein intake as the most expensive components of a meal, balance of the energy and protein, as well as defining the limit value of urea concentration in milk are a prerequisite for intensive production of goat’s milk.
Genetic parameters estimation for milking speed in Croatian Holstein cattle
Authors:   Croatian Agricultural Agency, Ilica 101, 10000 Zagreb, Croatia, Špehar Marija
Published: August 2023

Milking speed (MS) has a growing importance from a dairy management standpoint. Cows with slow MS require more labour, while cows with fast MS could be in greater risk for udder diseases. Although MS is considered as a trait of importance, little attention has been given to estimate genetic components for MS and its relationship with other traits. The objectives of this study were: 1) to estimate genetic parameters for MS in Croatian Holstein cattle; 2) to use them for the prediction of breeding values; and 3) to estimate proof correlations of MS with production and conformation traits in order to understand the interrelationships among traits. Data included 129,723 test-day records for 35,908 first calving cows taken from the central database of the Croatian Agricultural Agency. Pedigree file consisted of 85,605 animals. In order to improve the normality, logarithmic transformation for MS was used. Variance components where estimated by REML method using VCE 6 program. Statistical model included calving season, milking time, and milk yield class as fixed class effects, while age at first calving and days in milk were fitted as covariates. Random effects were: common herd-test day, permanent environmental and direct additive genetic effect. Common herdtest day and permanent environmental effect accounted 27 % and 15 % of variability. Direct additive genetic effect explained another 14 % of phenotypic variation for MS. Analysis of proof correlations between bulls and cows BV for MS with production and conformation traits showed low to mediate relationships. Most of these proof correlations were positive with an exception of teats length. Genetic evaluation for MS provide useful tool for breeding decisions due to moderate heritability of MS and the trait should be included in the total merit index in the future. In order to determine the appropriate economic weights for MS in the overall index, genetic correlations among MS and production and conformation traits should be estimated.
Milk yield, milk composition, fatty acid profile and indices of milk fat quality as affected by feeding with extruded full-fat soybean
Authors:   University of Veterinary and Pharmaceutical Sciences Brno, Faculty of Veterinary Hygiene and Ecology, Department of Animal Nutrition, Brno, Czech Republic, Křížová Ludmila
Published: August 2023

The aim of the study was to evaluate the effect of extruded full-fat soybean in diets of dairy cows on nutrient intake, milk yield, content and daily production of milk components, fatty acid (FA) profile and indices of milk fat quality. Four lactating Holstein cows were divided into control group fed a diet containing extruded rapeseed cake (R) and the experimental group fed a diet in which a part of extruded rapeseed cake was substituted by extruded full-fat soybean (RS). Dry matter intake (DMI), milk yield and milk composition were recorded. Milk FA profile was determined with subsequent calculation of atherogenicity index (AI), peroxidisability index (PI), desaturation indeks (DI) and spreadability index (SI) characterising quality of milk fat. Cows fed diet containing RS had higher DMI (17.8 kg/d) than cows fed diet containing R (16.8 kg/d, P<0.05). Milk yield in RS (19.5 kg/d) was higher compared to R (17.6 kg/d, P<0.05). Content of protein and casein was lower in RS than in R while content of lactose and urea was higher in RS than in R (P<0.05). Experimental diet (RS) compared to control (R) had higher (P<0.05) content of unsaturated FA (31.64 % and 30.69 %, respectively). Content of polyunsaturated FA in RS (4.03 %) was significantly higher (P<0.05) than in R (3.66 %) mainly due to differences in C 18:2n6c, C 18:3n6 and C 18:3n3 FA (P<0.05). Proportion of short-, medium- and long-chain FA was similar in both groups (P>0.05). PI was higher (P<0.05) in RS than in R being 5.54 and 5.06, respectively.
Quality of fresh and stored mares’ milk
Authors:   Department of Animal Breeding and Product Quality Assessment, Faculty of Veterinary Medicine and Animal Science, Poznań University of Life Sciences, Złotniki, ul. Słoneczna 1, 62-002 Suchy Las, Poland, Czyżak-Runowska Grażyna
Published: August 2023

Mares’ milk is characterised by unique nutritional profile. In this study, the microbiological analysis of mares’ milk was performed. The presence of total bacteria, total lactic bacteria, Lactobacillus spp., Streptococcus lactis, Salmonella spp. and coliforms was investigated. Moreover, the influence of refrigerated and frozen storage on the total bacteria count, vitamin C, acidity and colour of milk was examined. Pathogenic Salmonella spp. and coliforms were not detected in the raw milk. It was revealed that mares’ milk can be stored for 72 hours under refrigeration at a temperature of +4 °C without reducing its microbiological quality. Most of the physicochemical properties remained unchanged, while colour measurements demonstrated a change in b* value after 48 h of refrigerated storage. Vitamin C content remained relatively stable during a week-long storage. Freezing of milk improved its microbiological status and caused significant changes in all colour components (L*, a*, b*). The obtained results demonstrated that mares’ milk had a high microbiological quality, favourable chemical composition and high vitamin C content which make this product a valuable potential component of functional foods.
Outstanding pediatric surgeon Yuri Fedorovich Isakov (on the 100th anniversary of his birth)
Authors: Editorial Article
Published: August 2023

28 июня 2023 г. исполняется 100 лет со дня рождения выдающегося ученого и организатора здравоохранения, лидера отечественной детской хирургии второй половины ХХ столетия, академика, заслуженного деятеля науки Юрия Федоровича Исакова.
Congenital Central Hypoventilation Syndrome (Ondine’s Curse): Clinical Case
Authors: Adylov Teimur S. , Shestak Evgenii V.
Published: August 2023

Background. Congenital central hypoventilation syndrome (CCHS), or Ondine’s Curse, is rare, incurable and life-threatening disease characterized by autonomic nervous system disorders, it manifests with disability to maintain ventilation function during sleep. Sensitivity to hypoxia and hypercapnia is reduced in case of CCHS, thus, it leads to recurrent episodes of deep apnea. The world literature describes just over 1000 cases of this disease. Clinical case description. An infant born at 37th week of gestation, weight of 3330 g, had episodes of apnea and hypercapnia from the first day of life. CCHS was suspected by the 28th day of life after excluding other causes of respiratory disorders, and it was genetically confirmed by the 43rd day of life — pathogenic variant of PHOX2B gene was revealed. Mechanical ventilation has been initiated by the age of 1 month after disease worsening. Analysis of CCHS cases published in Russian-language medical literature was performed. Typical symptoms and timing of their manifestation, as well as the time before correct diagnosis were mentioned. Conclusion. Symptoms that can be suggestive of CCHS presence early after birth and can urge to perform all the necessary genetic testing that are crucial for timely treatment onset and for minimizing the negative effect of hypoxemia and hypercapnia on the child are described.
Drug Dosing in Pediatrics: Possible Approaches
Authors: Kolbin Alexey S. , Radaeva Kseniya S.
Published: August 2023

Drug dosing remains one of the topical issues of modern pediatrics. Insufficient number of clinical studies, vulnerable patient populations (preterm newborns, patients with renal and/or hepatic insufficiency, obesity), and high risk of polypragmasy create additional difficulties for practicing physicians. This review provides description of currently used approaches to drugs dosing in children. It has been shown that prognostic models should be used for solving drugs dosing issues regarding characteristics of young patients. Such models include: physiologically based pharmacokinetic modelling; population pharmacokinetic analysis; model-based precision dosing; modeling and simulation approach; use of real world data; and pharmacogenetic testing-based dosing. These models use information from preclinical and clinical stu
Resolution of the Independent Expert Council of The Union of Experts in the Field of Immunoprophylaxis
Authors: Editorial Article
Published: August 2023

Профилактика инфекционных заболеваний является одним из приоритетов в сфере охраны здоровья (Федеральный закон от 21 ноября 2011 г. № 323-ФЗ «Об основах охраны здоровья граждан в Российской Федерации» (действующая редакция, 2016 г.).
Psychoneurological Disorders in Children with Congenital Aniridia and PAX6-Associated Syndromes
Authors: Kupriyanova Olga S. , Karkashadze George A. , Zhurkova Natalia V. , Namova-Baranova Leila S. , Mamedyarov Ayaz M.
Published: August 2023

Congenital aniridia manifests with total or partial absence of the iris. The association of the disease with the PAX6 gene has been proven. Changes in the PAX6 structure lead to intrauterine pathology, visual organ malformation, malformation of master regulator proteins of organogenesis affecting various cells’ differentiation (central nervous system cells included). Such disorders result into the development of PAX6-associated syndromes with various brain malformations, neurological disorders, and systemic pathology (thyroid pathology, Wilms tumor, glucose intolerance). Isolated congenital aniridia is also accompanied by psychoneurological disorders. It can be associated with brain structures’ disorders during embryogenesis and with impact of external stress factors on the child (frequent medical checkup, surgical treatments). The psychoneurological disorders’ pathogenesis as well as congenital aniridia’s genetic mechanisms remain unclear. Thus, it is crucial to review new relevant data within the context of previously obtained information to gather full picture of the clinical signs of the disease and to improve the management of children with congenital aniridia.
Abnormal Uterine Bleeding in Adolescence Burdened with Severe Anemia: Clinical Case
Authors: Adamyan Leila V. , Sibirskaya Elena V. , Karachentsova Irina V. , Pivazyan Laura G. , Loshkareva Maria A. , Kirillova Yuliya A. , Murvatova Sabina K. , Murvatova Kamila K.
Published: August 2023

Background. Abnormal uterine bleeding (AUB) in adolescence is one of the urgent problems of medicine nowadays. It is on the 2nd place among all the reasons for hospitalization in gynecological departments, and its incidence among girls during puberty is 50%. Clinical case description. This is the clinical case of 15-year-old girl admitted to the gynecology department with complaints   on long-lasting bloody vaginal discharge, fatigue, dizziness. The diagnosis of «abnormal uterine bleeding in adolescence» burdened with iron deficiency anemia (IDA) was established according to laboratory and instrumental examinations. The patient underwent RBC-transfusion with specific buffy coat and was administered with hormonal hemostatic and anti-anemic therapy. Conclusion. We can conclude (with reference to this observation and the reviewed literature) not only that IDA is one of the most common complications of AUB in adolescence, but also what management should be used in such clinical cases.
Idursulfase Beta (Hunterase) Therapeutic Experience in a Patient with Mucopolysaccharidosis Type II
Authors: Vashakmadze Nato D. , Zhurkova Nataliya V. , Zakharova Ekaterina Yu. , Mikhaylova Ludmila K. , Babaykina Marina A.
Published: August 2023

Background. Mucopolysaccharidosis type II (MPS II, Hunter syndrome) is an X-linked recessive disease caused by lysosomal enzyme iduronate-2-sulfatase deficiency resulting in progressive glycosaminoglycans (GAG) accumulation in tissues (dermatan sulfate and heparan sulfate). GAG accumulation in cells leads to the development of progressive pathological disorders, malfunction of various organs and systems, early disability, and decrease in life expectancy. Enzyme replacement therapy (ERT) reduces the rate of life-threatening conditions development in patient. ERT would be more effective if it is prescribed early, especially at preclinical stage. This is the time when there are no severe irreversible changes in the cell, thus, pathogenetic therapy will decrease GAG accumulation in lysosomes, slow down the pathological process, and improve patient's condition. Clinical case description. Male patient diagnosed with MPS II was administrated with ERT idursulfase beta at the age of 6 months. It led to milder disease course compared to proband uncle who had similar mutation in the IDS gene, severe disease phenotype, and later initiation of ERT (at the age of 2.5 years). Conclusion. Early ERT initiation in patients with MPS II significantly slows down development of severe and life-threatening complications, increases the duration and improves the quality of life.
Instrukcje królewskie na sejmiki przedsejmowe doby panowania Michała I i Jana III
Authors:   Uniwersytet im. Adama Mickiewicza w Poznaniu, Dąbrowski Paweł Wojciech
Published: August 2023

The article is about the source analysis of royal services for pre-sejm assemblies with the help of multidimensional analyzes, statistical and comparative research. Therefore, it shows the documents from the reign of Michał I and Jan III in depth.
Obraz władców polskich w osiemnastowiecznych księgach silva rerum
Authors:   Uniwersytet Łódzki, Orzeł Joanna
Published: August 2023

The aim of this article is to present the view of Polish rulers by the nobility of the Polish-Lithuanian Commonwealth in the eighteenth century. These reflections were based on the silva rerum books written in the eighteenth century, containing separate sections on the history of the Polish Kingdom. As in the printed works, there is a noticeable slow change in the manner of descriptiveness – the abandonment of factual information in favour of an attempt to evaluate the ruler and the times of his reign. The painful reality of the successive partitions of the Polish-Lithuanian Commonwealth, and then its collapse, resulted in a more critical approach to certain rulers, but also to the mechanisms of governance.
Obraz powojennej Polski na łamach prasy polonijnej w Argentynie na przykładzie „Głosu Polskiego” z 1949 r.
Authors:   Uniwersytet Szczeciński, Pielacińska Nina , Seniów Adrianna ,   Uniwersytet Szczeciński
Published: August 2023

The aim of the paper is to reconstruct the image of socio-political changes in postwar Poland, which emerges from the press articles published in 1949 in the most important journal of the Polish community in Argentina, “Głos Polski”.
An analysis of a collection’s arrangement as a source of information on the collector
Authors:   Uniwersytet im. Adama Mickiewicza w Poznaniu, Mikołajczyk Paulina Anna
Published: August 2023

The article contains an analysis of objects and their the owner, as a result of which it was possible to partially recognize the space in which they were originally located, to prove the existence of the underlying idea and provided an opportunity to recreate it.
Synthesis and properties of polymer electrolytes based on polyurethane elastomer and lithium salts
Authors: Fedorov Nikita , Ulihin Artem , Uvarov Nikolai
Published: August 2023

Polymer solid electrolytes were obtained by swelling the polyurethane elastomer with solutions of lithium salts LiBF4 and LiClO4 in DMSO at different concentration of lithium salt. The swelling effect was found to decrease with the increase in the salt concentration, whereas, the ionic conductivity has a maximum of 6–8·10–4 S/cm at 5 wt.% lithium salt. The salt solutions incorporated into the polymer pores have melting points ranging from –10 to 2 °C and de-swelling takes place at low temperatures. The obtained polyurethane elastomer materials have a high conductivity and may be promising for use in flexible lithium polymer batteries.
Features of 12-lead electrocardiography in patients with critical aortic stenosis
Authors: Komlev A. E. , Blinova E. V. , Sakhnova T. A. , Saidova M. A. , Imaev T. E.
Published: August 2023

Aim. To study the features of 12-lead electrocardiography (ECG) in patients with critical aortic stenosis referred for transcatheter aortic valve implantation.

Material and methods. The study included 50 patients aged 76,6±6,5 years. The presence of intraventricular block, voltage criteria for left ventricular hypertrophy (LVH), fragmented QRS complex, and repolarization alternans were assessed on the ECG. The frontal QRS-T angle (fQRS-Ta) was estimated as the absolute value of the difference between the QRS axis and T wave axis.

Results. Intraventricular blocks were present in 10 (20%) patients: 8 (36%) patients with pulmonary hypertension (PH), 2 (7%) patients without PH (p=0,028). Voltage criteria for LVH were present in 24 (60%) patients. In the presence of voltage criteria for LVH, the mean aortic valve gradient, the left ventricular mass index (LVMI) and the aortic valve area (AVA) were significantly greater. Fragmented QRS complex in the chest leads was more common in patients with past myocardial infarction, intraventricular block, with PH. Strain pattern was present in 9 (23%) patients, while nonspecific repolarization changes — in 27 (67%) patients. Patients with strain pattern had significantly higher mean pressure gradient and more often had PH. Correlations were found between fQRS-Ta and mean pressure gradient (r=0,39; p=0,005), AVA (r=-0,40; p=0,004), LVMI (r=0,30; p=0,03). The fQRS-Ta was significantly greater in the presence of PH — 128±48o, while without PH — 97±49o (p=0,03).

Conclusion. In the studied group of patients with aortic stenosis, intraventricular block, fragmented QRS in the chest leads, strain pattern were more common in the presence of PH. In the presence of voltage criteria for LVH, LVMI, mean pressure gradient were significantly greater, while AVA — lower. The fQRS-Ta was significantly greater in the presence of intraventricular blocks, PH, as well as orrelated with mean pressure gradient and AVA.
Primary angiosarcoma under the guise of constrictive pericarditis: a case report
Authors: Chizhova O. Yu. , Bakulin I. G. , Skvortsova T. E. , Zueva D. S. , Boldueva S. A. , Zhorina O. M. , Yakovlev D. A.
Published: August 2023

Primary cardiac tumors are histologically heterogeneous and grow from the heart tissues. Their diagnosis is difficult due to the absence of pathognomonic signs, as well as the possibility of a long asymptomatic course. The authors present a case of late diagnosis of heart tumor in a young man, occurring under the guise of constrictive pericarditis with rapidly progressive heart failure, which ended in death 3 months after the first clinical symptoms. According to the autopsy, the histological picture and immunophenotype of the tumor corresponded to angiosarcoma.
Role of magnetic resonance imaging in the detection of myocardial fibrosis in life-threatening ventricular arrhythmias
Authors: Oleinikov V. E. , Averyanova E. V. , Vdovkin A. V. , Donetskaya N. A.
Published: August 2023

Sudden cardiac death (SCD) is a major medical, economic and social problem. Survival after SCD remains low. Its leading mechanism is fatal ventricular tachyarrhythmias. The only highly effective aid remains an implantable cardioverter defibrillator (ICD). According to modern concepts, myocardial fibrosis (MF) is the leading cause of life-threatening ventricular arrhythmias. Magnetic resonance imaging (MRI) has become the standard for non-invasive MF imaging and one of the leading methods for its quantification, which is why this method is recommended for determining indications for ICD implantation. MRI can show the scar location, which should be taken into account when placing the lead, and determine its size, which predicts the effectiveness of ICD implantation. Identification of MF in patients with life-threatening ventricular arrhythmias is an important area of research aimed at identifying the risk of SCD. Delayed contrast-enhanced MRI can be considered as a marker to improve SCD risk stratification.
Lipoprotein(a) in the diagnosis of cardiovascular risk. The values of lipoprotein (a) and apolipoprotein B in the adult population of Krasnoyarsk
Authors: Emelyanchik V. S. , Marilovtseva O. V. , Khomchenkov R. V. , Moiseeva A. M. , Chernova A. A. , Emelyanchik E. Yu. , Nikulina S. Yu. , Protopopov A. V.
Published: August 2023

Aim.To study the prevalence of elevated concentrations of lipoprotein (a) (Lp(a)) and apolipoprotein B (apoB) associated with high cardiovascular risk in a random sample of the adult Krasnoyarsk population.

Material and methods.Lp(a) and apoB concentrations were determined by the immunochemiluminescent method using an automated modular Cobas 8000 platform with biochemical module c702 (Roche Diagnostic, Switzerland). We examined 263 people aged 18 to 58 who agreed to expand the standard screening by Lp(a) and apoB determination.

Results.We found that high and very high levels of Lp(a) are found in 12,9% of the examined, while in women the median value was significantly higher than in men (p=0,044). In addition, 11,4% of study participants had high apoB values, regardless of sex; 3,4% of the subjects had a combination of elevated levels of ap B and Lp(a).

Conclusion.Screening for Lp(a) and apoB reveals dyslipidemia associated with high cardiovascular risk in 24,3% of working-age people
Ballistic impact: predicting penetration depth in ultra-high-performance concrete targets
Authors: Das Nabodyuti , Darshan Bhaskar , Nanthagopalan Prakash
Published: August 2023

This paper presents the application of an artificial neural network (ANN) model for predicting the penetration depth under projectile impact in ultra-high-performance concrete (UHPC) targets containing steel fibres. Despite the availability of a large number of existing empirical models, the prediction of penetration depth remained inconclusive, partly due to the phenomenon's complexity and partly due to the limitation of statistical regression. From the results of this study, it is evident that the ANN model is capable of predicting the penetration depth of UHPC more accurately than other machine-learning (ML) models (linear regression, decision tree regression and random forest regression) and empirical formulae. The ANN model achieved a lower root mean square error (RMSE) of 11.68 compared to the other ML models (RMSE: 16.66–19.74) and empirical equations (RMSE: 25.17–53.42), when applied to the test data set. The velocity, impact energy, diameter of the projectile and thickness of the UHPC targets are the most significant parameters (P-value <5%) for predicting the penetration depth using ANN and multiple linear regression models.
ICOLD 2023, Gothenburg, Sweden: regulation and management
Authors: Prendergast Maddie A.
Published: August 2023

At the International Commission of Large Dams 2023 symposium, session (S3-A) covered regulation and management. Papers highlighted lessons learned from evaluating different legislative frameworks, some of which were particularly pertinent to the UK dam industry. The underlying context for all papers presented was new or changing legislative environments. The key themes of the session have been grouped in this briefing note, selecting interesting contributions accordingly.
Integración de la práctica y la teoría de “convertirse en madre”, de Ramona Mercer, desde una narrativa de enfermería
Authors:   Universidad Cooperativa de Colombia, Oyola Naranjo Dora Janette
Published: August 2023

Esta nota de clase es una guía por utilizar en la práctica formativa y el proyecto formativo, que facilita la comprensión de los procesos para integrar teoría, investigación y práctica en escenarios reales de salud, y para afianzar los conocimientos y las bases científicas de la disciplina de enfermería en los alumnos. Está diseñada para el curso Cuidado de Enfermería a la Mujer y el Recién Nacido, pero puede guiar otros campos del cuidado. Es una revisión de la teoría de Ramona Mercer sobre la adopción al rol materno, la cual ha tenido una transición que se aprecia en lo que es ahora la teoría de “convertirse en madre”, por lo que es importante conocer sus cambios en función de favorecer su análisis. Posteriormente, con una situación de enfermería se analizan los conceptos centrales de esta teoría y la relación existente entre sus definiciones y la experiencia narrada, para luego generar una propuesta de plan de atención de enfermería que sea coherente con los planteamientos teóricos y el contexto de la situación. Se incluye una unidad sobre depresión posparto, que es pertinente revisar dado el alto riesgo de incidencia para esta población y por cuanto la enfermería debe adoptar medidas tendientes a la identificación de los síntomas en las salas de trabajo de parto.
Introduction: Posthumanist Gender Theory—A Very Rough Account
Authors: Babka Anna , Kernmayer Hildegard , Lingl Julia , Schmutz Marietta
Published: August 2023

This special collection, edited by Anna Babka, Hildegard Kernmayer, Julia Lingl, and Marietta Schmutz cuts across current positions and developments within the frame of what can be called posthuman gender theory, thereby questioning humanist-epistemological categories that continue to shape Western societies and their systems of knowledge production. Posthuman gender theory inscribes itself into the discussion about a "conditio posthumana." Thereby, the traditional essentialism of a biologically based two-gender system is questioned anew. At the same time, the "humanistic" idea of the superiority of man (as a male subject of domination) gives way to a post-anthropocentric conception of reality, according to which binary hierarchical oppositions such as man/animal or man/machine dissolve. This collection among others comprises transdisciplinary examinations of novels, comics, and other cultural or social phenomena and aims to participate in the ongoing development of posthumanist thinking in relation to gender and queer theory formation.
The Plural is Unmarked: Evidence from Turkish, Hungarian and German
Authors: Yatsushiro Kazuko , Geçkin Vasfiye , Harmati-Pap Veronika , Alexiadou Artemis , Sauerland Uli
Published: August 2023

Quantity distinctions are morphologically indicated in the majority of languages.However, the marking of these distinctions exhibits a high degree of cross-linguistic variation with respect to the number of quantity categories, their agreement properties, and the morphemes themselves. Furthermore, number marking on numerically quantified nouns varies across languages: for instance, while German and English use plural number marking with numerals other than “one” (for example, “two books”), Turkish and Hungarian use singular number marking with all numerals. Recent work has discussed how to explain number marking with numerals. In particular, Bale and Khanjian (2014) propose that the quantity concepts of the two types of languages vary semantically. We present novel evidence from a cross-linguistic study of Hungarian, Turkish and German child language, and argue that the quantity concepts do not vary, and the variation between languages must have a morphosyntactic explanation. 
Acoustics of stress and weight in Central Alaskan Yup’ik
Authors: Alden McKinley , Arnhold Anja
Published: August 2023

In Central Alaskan Yup’ik, syllables with long vowels are always stressed, light syllables alternate stress, but only certain closed syllables are stressed. The acoustic correlates of stress, however, have only been the subject of one small-scale preliminary study so far. Moreover, there are divergent accounts of how phonological phenomena such as gemination and syllable closure affect weight. This article presents an acoustic investigation of gemination, stress, and phonemic length. Six Yup’ik recordings were annotated, resulting in a dataset of 2,602 syllable onsets and 2,282 vowels, which were then modelled using linear mixed-effects models. The first part of the study, examining the distribution of gemination as a metrical-adjacent phenomenon, revealed that singleton onsets were shorter than geminated onsets both within feet and across foot boundaries. The main study showed that stressed vowels were longer, louder, and, for short vowels only, higher in f0 than unstressed vowels, while long vowels were longer, louder, and featured greater f0 falls than short vowels. These results corroborate the literature that asserts that long, short unstressed, and short stressed vowels are all produced distinctively, and moreover, that vowel duration is affected by iambic lengthening and syllable closure. The identification of stress correlates and other metrical behaviors examined here set the stage for future prosodic work on Yup’ik.
“Can You Complete Your Delivery?” Comparing Canadian and European Union Legal Statuses of Platform Workers
Authors: Gebert Raoul
Published: August 2023

In December 2021, the European Commission proposed a directive creating five criteria for the presumed classification of platform economy workers as salaried employees. The issue is timely, of course, as the digital organisation of work continues to grow rapidly. Our article contrasts the merits and limitations of this initiative to the Canadian experience concerning so-called independent contractors in the platform economy. In fact, Canadian labour law has long recognised a third status of workers—dependent contractors. It permits collective bargaining, while platform workers remain autonomous, notably for tax purposes. Immediately, the striking similarities between the European Union’s five criteria and judicial tests applied by Canadian labour tribunals seem to indicate that both entities are moving in the same direction. However, the federal structure of labour law in Canada and the single market’s social dimension also pose important challenges regarding the uniform implementation of new protections. Based on recent fieldwork in Toronto, and as the European Union directive moves into the approval and implementation stages, our article addresses the research question of how basic labour rights in the platform economy progress similarly (or differently), and which actors are driving the change on each side of the Atlantic. We argue that this policy field provides labour market actors with opportunities for “institutional experimentation” navigating the openings and limitations of federalism.
Malvaceae no Parque Nacional do Iguaçu: lista das espécies e chave de identificação
Authors: Vieira Helena , Temponi Lívia , Caxambú Marcelo , Lima Laura
Published: August 2023

O presente trabalho consiste em uma listagem de espécies de Malvaceae sensu lato para o Parque Nacional do Iguaçu (ParNa Iguaçu), localizado no oeste do estado do Paraná. Entre agosto de 2019 e fevereiro de 2020, foi realizado um inventário digital por meio das plataformas JABOT, REFLORA e Specieslink, bem como coletas nas principais trilhas da área estudada. As espécies coletadas foram incorporadas no herbário Evaldo Buttura (EVB), onde foram identificadas por meio de consultas à literatura especializada. Registrou-se para o ParNa Iguaçu 20 espécies de Malvaceae distribuídas em 14 gêneros, dentre os quais os mais representativos foram Pavonia (3 spp.) e Sida (3 spp.), com S. rhombifolia como nova ocorrência para a área. Do total amostrado, 10 espécies foram encontradas em áreas de Floresta Estacional Semidecidual, duas foram registradas somente na Floresta Ombrófila Mista e oito foram encontradas em ambas as formações. Com relação aos hábitos de crescimento das espécies, seis são árvores, seis arbustos, seis possuem o porte herbáceo a subarbustivo e apenas duas são trepadeiras. Nenhuma das espécies encontradas está ameaçada de extinção no Brasil. Ademais, Callianthe striata é a única espécie endêmica do Brasil e, com exceção da exótica Malvaviscus arboreus, todas elas são nativas na Mata Atlântica.
Biomimetic Proteoglycans Molecularly Engineer Cartilage Pericellular Matrix And Can Be Leveraged As A Multi-Functional Drug Delivery Platform
Authors:   , Kahle Elizabeth , Marcolongo Michele S. , Han Lin
Published: August 2023

Osteoarthritis (OA) is the most common cause of disability in older adults, afflicting an estimated 10-15% of adults aged over 60. In early OA, degeneration of cartilage pericellular matrix (PCM), a 2-4 [mu]m thick region surrounding chondrocytes that facilitates cross-talk between the extracellular matrix (ECM) and chondrocytes in the process of mechanotransduction, is one leading event of disease initiation. Controlled, in part, by an inflammatory response of catabolic enzymes, critical biomolecules of the PCM, such as proteoglycans, are early casualties of the disease resulting in reduced PCM micromodulus, abnormal cellular mechanotransduction, and a corresponding increase in a catabolic metabolism. Successful regeneration of degraded OA cartilage has been challenged by our limited capability of regenerating the biomechanical and biophysical cross-talk between the ECM and chondrocytes. This renders the pericellular matrix (PCM), the immediate chondrocyte microniche, an emerging target for modulating chondrocyte mechanotransduction in both healthy and OA cartilage. This thesis utilizes the biomimetic proteoglycan BPG10, which has a "bottle-brush"-like nanoarchitecture mimicking the native proteoglycan aggrecan, and is comprised of 7-8 chondroitin sulfate glycosaminoglycan chains chemically attached to a poly(acrylic acid) core (MW ~10 kDa). When infiltrated into bovine cartilage explants ex vivo, BPG10 diffused throughout the matrix and was preferentially localized in the PCM. Distribution, association, and retention of BPG10 in cartilage PCM in vivo and ex vivo was shown to be possible through adhesive inter-molecular interactions with a PCM predominant, native proteoglycan, aggrecan. This localization led to increased PCM micromodulus, and in turn, significantly enhanced chondrocyte intracellular calcium signaling activities, a marker of mechanotransduction. When infiltrated into both human OA and normal cartilage, BPG10 also localized in the PCM to a varying degree and mechanically enhanced this cellular microniche, indicating a translational potential for BPGs to restore degenerative PCM mechanics and rescue disrupted chondrocyte mechanosensitive activities. Given its capability of localizing in the PCM, BPG10 was thus leveraged as a drug delivery platform for the potential disease modifying OA drug (DMOAD) dexamethasone to increase its therapeutic efficacy while simultaneously providing mechanical and mechanobiological support to the PCM. Through the combination of local delivery of dexamethasone and mechanical reinforcement of the cellular microniche via BPG10, the degree of cartilage degradation was ameliorated in an ex vivo inflammatory cartilage model by the BPG10-drug constructs. Collectively, these outcomes have provided a new path for molecular engineering of cartilage pericellular matrix and attenuation of disease progression in OA.
Rigorous Approximation of Lattices with Random Materials by Wave Equations
Authors:   , McGinnis Joshua Andrew , Wright Jay Douglas
Published: August 2023

Within the framework of "coarse-graining", we prove the macroscopic dynamics of a lattice composed of random materials (springs and masses) converges strongly with probability one (a.s.) to an effective wave equation as the initial conditions become long relative to the lattice spacing. More concretely, this means an effective wave equation approximates the dynamics of the lattice well, relative to the size of the initial conditions on time scales proportional to the length scaling of the initial conditions. We prove such a result for a one dimensional lattice with random masses and springs and a two dimensional square lattice with random masses. In addition, for the one dimensional lattice, we also prove a convergence in mean. For the two dimensional lattice, we discuss how the dimension of the lattice effects convergence rate in the case when the materials are random. We also give numerical results regarding a KdV approximation of an FPUT system with random masses where the masses are chosen with a technical condition we call transparency.
Associations Between Parental Criticism and Dysregulated Eating in Adolescents with and without Loss of Control
Authors:   , Trainor Claire M. , Manasse Stephanie M
Published: August 2023

Adolescents with overweight/obesity and binge spectrum eating disorders often experience dysregulated eating behaviors such as overeating, loss of control eating (LOC), and dietary restraint. Understanding maintaining mechanisms, particularly family factors, of these behaviors is essential. Parental criticism has been linked to eating pathology in adolescents, but its momentary association with dysregulated eating behaviors has not been studied. Therefore, this study aimed to examine the relationship between momentary criticism and dysregulated eating behaviors in adolescents with overweight and obesity. Thirty-seven adolescents (aged 14-18) with overweight and obesity (BMI% >85.0) and their parents participated in this study, completing seven days of ecological momentary assessment (EMA). Participants responded to seven surveys a day throughout the EMA period, assessing overeating, LOC, dietary restraint, and criticism. Results revealed relatively low levels of criticism within the sample and low within-subjects concordance between parents and adolescents regarding perception of criticism. Adolescents who reported LOC at any point in the EMA time period were more likely to endorse overeating, restraint, and both adolescent- and caregiver-reported criticism than those without LOC. Additionally, adolescent overeating at one time point, but not LOC or dietary restraint, was associated with elevated likelihood of parental criticism at subsequent timepoints, which was moderated by EMA LOC status; individuals with LOC were more likely to report parental criticism, while individuals without LOC were less likely to report parental criticism. Furthermore, adolescent-reported criticism was linked to increased likelihood of engaging in dietary restraint at subsequent timepoints. No other significant findings emerged. This study is the first to examine momentary associations between parental criticism and eating behaviors in adolescents with overweight and obesity. This study highlights the importance of understanding momentary criticism and its relationship with dysregulated eating behaviors in adolescents with overweight and obesity. The findings suggest that adolescent overeating is associated with subsequent parental criticism, particularly for those with LOC. Moreover, parental criticism is associated with subsequent restraint. However, more research is needed to fully understand the role of momentary criticism in dysregulated eating behaviors, and future directions for this research are discussed.
Um sistema informatizado para controle do uso de antimicrobianos
Authors: Santos Nilton Freire , Brito Filho Mário Toscano de , Santos Filho Lauro
Published: August 2023

Este trabalho apresenta um sistema informatizado para controle e monitoração do uso de antimicrobianos em hospitais, que torna disponíveis aos profissionais de saúde as informações e orientações necessárias para o uso adequado dessas drogas na prática clínica [...].
Caracterização de corpos cerâmicos de uma mistura de argila, tijolos refratários e lama vermelha. Parte I: um estudo preliminar
Authors: Mercury José Manuel Rivas , Moraes Elton César , Monteiro Celina Margarida De Oliveira
Published: August 2023

No presente trabalho, estuda-se de forma preliminar a utilização de rejeitos industriais nocivos ao meio ambiente procedentes da indústria de alumínio, visando a sua utilização na indústria cerâmica industrial [...].
Diseño, producción e implementación de un Objeto Virtual de Aprendizaje para la enseñanza de sistemas de información en Ingeniería Industrial
Authors: Torres-Barreto Martha Liliana , Lobo-Rueda Miguel Ángel
Published: August 2023

En relación con los cambios y estrategias necesarias en el siglo XXI, y con la relevancia de la integración de las TIC en el desarrollo de contenidos se plantea el diseño de una herramienta gamificada de aprendizaje, Objeto Virtual de Aprendizaje (OVA). Este permite la mimetización de contenidos dentro de una narrativa con una divulgación cercana y cautivadora de temas tecnológicos, pensada para estudiantes que cursan materias centradas en el ámbito de la tecnología y con aplicaciones dentro del programa de Ingeniería Industrial. La herramienta está apoyada en contenido multimedia, lo que permite facilitar y mejorar la experiencia de aprendizaje del estudiante, así mismo, desarrollar la capacidad de identificar y asociar conceptos básicos de los sistemas de información, y reconocer su papel en distintas áreas empresariales.
Proceso de Enfermería Incluyente
Authors: Rueda-Díaz Leidy Johanna , Cárdenas María Vivina , Marquez-Herrera Marisela , Reyes-Arias Luis Eduardo , Arias-Gamarra Mayra Alejandra , Manosalva-Ticora Daniel Eduardo
Published: August 2023

La Escuela de Enfermería recibe estudiantes de poblaciones indígenas, los cuales, presentan dificultades de lecto-escritura derivadas de su formación académica. Esto debido a que, los estudiantes indígenas cursan su educación básica primaria y secundaria en lengua materna, lo que impacta negativamente en su desempeño académico en la Universidad. Puesto que, en esta, las asignaturas son desarrolladas en un idioma diferente a su lengua materna. Por lo anterior, se identificó la necesidad de crear diferentes estrategias visuales y auditivas que facilitaran el aprendizaje de estos estudiantes. En ese sentido, el objetivo de este trabajo fue desarrollar y evaluar la implementación del aula virtual Proceso de Enfermería II, del 2019, desde la perspectiva de los estudiantes que participaron en la misma.
OVA Simulador de Costos
Authors: Arias-Góngora Dora
Published: August 2023

Los costos de producción requieren del manejo y conocimiento de aspectos laborales, tributarios, contables y financieros, los cual hace compleja su determinación para el estudiante. Además, otra dificultad se presenta por el uso de materiales en formato plano, poco atractivos y con más temática que la requerida en su primer curso, lo que demanda tiempo para sintetizar y abordar lo delimitado en la asignatura Costos. Por otra parte, el realizar el Costeo del Plan Emprendedor es complejo por la cantidad de cuadros a elaborar y carencia de experiencia laboral de muchos estudiantes en áreas de producción y administración. Por lo tanto, ante estas dificultades, el Objeto Virtual de Aprendizaje (OVA) Simulador de Costos, presenta materiales para orientar la teoría y, de igual forma, las plantillas de Excel, con fórmulas y observaciones para la práctica de Costeo, con la finalidad de optimizar el tiempo de registro de datos.
Implementación de la herramienta Programa Prático para Formulação de Ração (PPFR) – versão Microsoft Excel© 2010 en la formación académica del área de nutrición animal del programa de Zootecnia adscrito al Instituto de Proyección Regional y Educación a Distancia (IPRED)
Authors: Avendaño-Vásquez Leonardo , Rodriguez-Toro Jorge Andres
Published: August 2023

En la nutrición animal, los requerimientos, materias primas y costos de producción de especies de interés zootécnico forman parte del conocimiento del estudiante del programa de Zootecnia. La creación de planillas electrónicas desarrolladas a partir del programa WUFFDA con el fin de suplir las necesidades de los animales mediante el modelo linear y no linear permite cumplir con las competencias según el PEP. El objetivo del proyecto de aula consistió en implementar la herramienta Programa Prático para Formulação de Ração (PPFR) – versão Microsoft Excel© 2010 en la formación académica del área de nutrición animal del programa de Zootecnia, adscrito al Instituto de Proyección Regional y Educación a Distancia (IPRED), en la sede Málaga, de la Universidad Industrial de Santander.
Calidad de la leche cruda en plataforma
Authors: Corredor-Anaya Astrid Selene
Published: August 2023

En los procesos de aprendizaje que se orientan en el Instituto de Proyección Regional y Educación a Distancia (IPRED) se requieren procesos dinámicos, para ello se tienen estrategias digitales que pueden ser herramientas en el fortalecimiento de competencias, como lo son los objetos virtuales de aprendizaje. En esta experiencia se muestra la utilización de un Objeto Virtual de Aprendizaje (OVA) para el desarrollo y afianzamiento de las competencias que corresponden al módulo de transformación de productos de origen animal con el tema de calidad de la leche cruda en recepción, donde se analiza las materias primas aptas para su procesamiento y reconoce el procedimiento de toma de muestras para el laboratorio. Este OVA tiene como objetivo explicar a los estudiantes los conceptos generales de la leche y explicar las diferentes pruebas de plataforma y de laboratorio.