bluuebunny/crossref_metadata_2025 huggingface dataset:
Application of Machine Learning-Based Electrochemical Deposition Models to CMP Modeling
Authors: Ghulghazaryan Ruben , Piliposyan Davit , Shoyan Misak , Nersisyan Hayk
Published: April 2021

Chemical mechanical polishing/planarization (CMP) is the primary process used for modern integrated circuits (IC) manufacturing. Modeling of the post-CMP surface profile is critical for detecting planarity hotspots prior to manufacturing and avoiding fatal failures of chips. Electrochemical deposition (ECD) is a key process for the void-free filling of interconnection wires and vias in modern chips. Large surface topography variations generated after ECD affect the post-CMP surface profile. In this paper, several machine learning approaches are used to model surface profiles after ECD that are used as input to CMP models. Different combinations of deep neural networks, long-shortterm-memory (LSTM) recurrent networks, convolutional neural networks and XGBoost algorithms are investigated and compared. The model based on the XGBoost library showed superior performance and accuracy
Soil successions of carbic podzols (arenic) and umbric podzolsof sand forest steppe at change of forest-forming rocks
Authors:   ООО ", Saakian Alexander ,   БАЛАНС ПРОФИ"
Published: April 2021

The article presents the data of ecological-soil survey of carbic podzols (aerenic) and umbric podzols of sandy pine forests of the Kursk agglomeration. The data on the transformation of morphological, physical and physicochemical properties of the studied soils in the succession series "pine forest - mixed forest - broadleaf forest" are presented. It has been established that when the monodominant plantations of Scots pine are replaced by deciduous species, the soil-forming processes change - podzolic to sod. The settling of deciduous species in pine plantations gradually leads to attenuation of the podzolic process, the development of processes of accumulation of humus and mineral nutrients in the soil profile, which contributes to an increase in the ecological stability of azonal carbic podzols (aerenic) and sandy umbric podzols in the conditions of the forest-steppe zone. Keywords: MICROEVOLUTION OF SOILS, TERRACE ABOVE FLOOD-PLAIN, PODZOLY PROCESS, SODDY PROCESS, SOIL SUCCESSION
ТЕСТОВІ ТЕХНОЛОГІЇ ОЦІНЮВАННЯ КОМПЕТЕНЦІЇ МАЙБУТНІХ ФАРМАЦЕВТІВ НА ЗАНЯТТЯХ
АНАЛІТИЧНОЇ ХІМІЇ
Authors: ЧЕТВЕРТАК Тетяна
Published: April 2021

Pedagogical sciences
СУЧАСНІ АСПЕКТИ ДІАГНОСТИКИ ТА ЛІКУВАННЯ ВИРАЗКОВОЇ ХВОРОБИ
Authors: НАУМЕНКО Олександр , МОЙСЕЄНКО Валентина
Published: April 2021

MEDICINE
MODELING RESISTANCE FORCES AND DRILL COLUMN STICKING EFFECTS IN CURVILINEAR
BOREHOLE CHANNELS
Authors: LEVKIVSKA Liydmyla
Published: April 2021

PHYSICAL AND TECHNICAL & MATHEMATICAL SCIENCES
НОВІТНІ СОЦІАЛЬНО-КОМУНІКАТИВНІ ДОСЛІДЖЕННЯ ТА МЕТОДИЧНЕ ЗАБЕЗПЕЧЕННЯ ДИСТАНЦІЙНИХ
ТРЕНІНГІВ У УМОВАХ ПАНДЕМІЇ COVID-19
Authors: ЧЕКМИШЕВ Олександр
Published: April 2021

SOCIAL COMMUNICATIONS
ЛІПІДИ ТА ВІРУЛЕНТНІСТЬ ПАТОГЕННИХ І НЕПАТОГЕННИХ МІКОБАКТЕРІЙ
Authors: ТКАЧЕНКО Олексій , БІЛАН Марина , ГЛЕБЕНЮК Володимир , АЛЕКСЄЄВА Наталія , ГАВРИЛІНА Олена
Published: April 2021

Veterinary medicine
AGILE PHILOSOPHY AS A MECHANISM FOR FORMATION OF HIGH-LEVEL VALUES AND CHANGE IN
ORGANIZATION
Authors: KORZH Nataliia , SOKOLOVSKA Valentyna , BABCHINSKA Olena
Published: April 2021

Economic sciences
СОВРЕМЕННОЕ СОСТОЯНИЕ ЭКОНОМИК ЛИТВЫ
Authors: СИМАНАВИЧЕНЕ Жанета
Published: April 2021

ECONOMIC SCIENCES
Analisis Faktor Yang Mempengaruhi Belanja Daerah Kabupaten Sidoarjo Tahun Anggaran 2009 -2018
Authors: Pratama Bemby Agung
Published: April 2021

Abstrak:

                Penelitian ini bertujuan untuk menganalisis pengaruh Pertumbuhan Ekonomi,PAD dan DAU terhadap Belanja Daerah di Kabupaten Sidoarjo pada tahun 2009-2018. Penelitian ini merupakan penelitian kuantitatif dengan desain penelitian deskriptif dan Asosiatif.Data yang digunakan yaitu data time series PAD, dana perimbangan, dan belanja daerah pada website DJP Kemenkeu dan Badan Pusat Statistik (BPS) Kabupaten Sidoarjo tahun 2009-2018. Teknik pengumpulan data yaitu secara sekunder dengan mengumpulkan beberapa refrensi dari website DJP Kemenkeu dan BPS Sidoarjo.Teknik analisis data menggunakan statistika deskriptif, uji asumsi klasik, uji korelasi sederhana dan berganda, uji regresi dan uji hipotesis parsial (uji t) dan uji hipotesis simultan (uji F) dengan bantuan software SPSS.Hasil analisis menunjukkan secara uji (t) parsial Dana Alokasi Umum(DAU) berpengaruh signifikan terhadap belanja daerah,sedangkan pertumbuhan ekonomi dan Pendapatan Asli Daerah (PAD)  tidak berpengarauh secara signifikan terhadap belanja daerah. Secara uji (f) simultan pertumbuhan ekonomi,pendapatan asli daerah (PAD) dan dana alokasi umum (DAU) berpengaruh signifikan terhadap belanja daerah.
Pengaruh Kualitas Pelayanan Dan Keputusan Terhadap Loyalitas Pelanggan
Authors: Azrullah Muhammad Mashudi
Published: April 2021

The focus of this research is the influence of service quality and satisfaction on customer loyalty with a case study in “Café : Kofi” Bangil. This research method is quantitative, the subject of this study are customers of “Café : Kofi” Bangil. The sampling technique used was purposive sampling. With a total of 60 respondents. The result show multiple liniear regression test Y + 0,180 + 0,041 + 0,941 + e. shows that the influence of service quality variables is 0,041 an the effect of satisfaction variables is 0,941. Thus the more dominant variable influencing customer loyalty is the satisfaction variable. T-test results indicate that the service quality variable (X1) has no partial effect and is not significant. While the satisfaction variable is partially significant. Test the coefficient of determination R2 obtained 0,899 or 89,9% this means that customer loyalty is influenced by satisfaction variables.

 Keywords : Quality Of Service, Satisfaction
Pengaruh Model Kepemimpinan dan Motivasi Kerja Terhadap Kinerja Pegawai Aparatur Sipil Negara
Authors: Mutohar Achmad
Published: April 2021

The focus of this research is the influence of leadership models and work motivation on the performance of civil servants in the state. This research was conducted at the Sukomanunggal office, Surabaya, East Java. The research was conducted from May to July 2019. The type of research was primary data using a questionnaire. The population in this study includes 30 civil servants of the Sukomanunggal sub-district, Surabaya, who are also the sample in this study. The result shows that partially the leadership model variable and the work motivation variable have a significant effect on employee performance, and simultaneously the independent variable also has a significant effect on the dependent variable with a sig of 0,000. With multiple linear regression analysis Y = 0,531 + 0,375X1 + 0,454X2 + 2. As well as the coefficient of determination of 55,7%, while the remaining 44,3% is influenced by other factors outside the X variable used.

 Keywords: Leadership Model, Work motivation, Employee Performance
High and ultra low concentrations of Mercuric chloride initiate their specific action on binding sites of invertase and modify its interaction with sucrose
Authors: Konar Atheni , Sarkar Tandra , Sukul Nirmal Chandra , Sukul Abirban , Chakraborty Indrani , Ray Sriparna
Published: April 2021

Background: Mercuric chloride is known to inhibit the activity of enzymes. It is used in homeopathy at ultra low concentration (ULC) and is known as Mercurius corrosivus (Merc cor). ULCs of Merc cor are reported to promote enzyme activity. Objective: To see whether the mother tincture (?) of Merc cor and its ULCs interact with an enzyme invertase at its binding sites and influence enzyme’s action on its substrate sucrose. Methods: Merc cor ? (0.15 M HgCl2) was diluted with deionized and distilled (DD) water 1:100 and succussed 10 times to prepare Merc cor 1 cH or 1st potency. This potency was further diluted and succussed in 200 and 1000 steps to prepare 200cH and 1000cH potencies, respectively. Merc cor 200 cH and 1000cH were prepared in 90% ethanol. The two potencies and blank 90% EtOH were diluted with DD water 1:1000 to minimize ethanol content to a negligible amount 0.09%. The control was DD water (55mM). The drugs, EtOH and water control were mixed separately with 0.037 mM invertase in DD water. Using an isothermal calorimetry (ITC) instrument the substrate sucrose (65mM) was injected at 2 µl every 2 min into 300 µl invertase solution 20 times at 25 0C. Molecular modeling study was done to predict possible binding sites and nature of binding between the enzyme and HgCl2 and between the enzyme and water. Potencies after dilution are virtually water. Fluorescence spectra of invertase (4µM) mixed with drug/control solutions were also obtained to see the effect of drugs on protein folding. Results: Thermodynamic parameters like binding constant, change in enthalpy, entropy and Gibbs free energy showed marked variation in treatment effects on the enzyme. Molecular modeling study also shows variation in binding between invertase and HgCl2 and between invertase and water. Fluorescence spectra show variation in quenching related to different treatments. Conclusion: Merc cor mother tincture and its potencies interact at different binding sites of invertase and modify the enzyme’s action on sucrose. Drug solutions induce conformational changes in the enzyme.
A review on preclinical studies conducted with Homeopathic medicine Cephalandra indica as an Anti-hyperglycemic agent
Authors: Wakte Dr. Mitesh Santosh , Patil Aditya Dilipkumar
Published: April 2021

Background –

Diabetes Mellitus a metabolic disorder affects the secretion of insulin from pancreas leading to hyperglycemia, if uncontrolled leads to complications triggered by free radical formed after oxidative stress. Homeopathic medicine Cephalandra Indica has shown antidiabetic activity in various potencies performed on preclinical studies on diabetic rat model. The present review highlights the pharmacological profile of homeopathic preparations Cephalandra Indica on preclinical studies and calculating the probable human equivalent dosage from preclinical studies for the pilot studies.

Method –

Articles published between January 1988 and December 2018 was included in review. Databases like PubMed – Medline, Google scholar were used for collecting the articles. Keywords like ‘Homeopathy’ or ‘Homoeopathy’, ‘Invitro’, ‘Invivo’ and ‘Cephalandra Indica’ were used. SABEH criteria were implemented for assessing methodology quality of articles.

Results –

Seven full text articles were included in review which had six Invivo studies and one Invitro study. This review article provided the scientific validation of high diluted homeopathic medicines pharmacological activity of Cephalandra Indica and probable mechanism of action confirmed through preclinical studies. Conversion of dosage from animal model to human dosage for pilot studies has been hypothetically proposed.

Conclusion –

Homeopathic medicine Cephalandra Indica has a therapeutic and safety profile with no toxicity observed in preclinical studies. The proposed hypothesis of conversion of dosage needs to be validated for further studies.
Management of early years of simple and mucopurulent chronic bronchitis with pre-defined Homoeopathic medicines – a Prospective Observational Study with 2-Years Follow-Up
Authors: Varanasi Roja , Gupta Jaya , M Prakash Rao , K Raju , Prasad R VR , Sadanandan Gopinadhan , Arya J S , Mandal B K , Singh Mohan , Singh Vikram , Nayak Chaturbhuja , Pramanik Abhishek , Kumar Arvind , Varanasi Roja
Published: April 2021

Background: Simple and mucopurulent chronic bronchitis (SMCB) is characterized by recurrent mucoid or mucopurulent sputum production in absence of localized suppurative disease. This observational open label study was undertaken to evaluate the effects of homoeopathic medicine in SMCB.

Methods: 1902 patients were screened from 07centres out of which 1305 were excluded. 597 patients were enrolled as per the inclusion and exclusion criteria. A total of 14 pre-defined homeopathic medicines were shortlisted for prescription after repertorizing the pathological symptoms of SMCB. Outcomes were changes in symptoms score using chronic bronchitis symptom scale (CBSS) and changes in FEV1/ FVC ratio using spirometry over a period of two years. Appearance of any change (relief/ worse)/ status quo was immediately followed by placebo/ change in dilution/ change in remedy. Statistical analysis was done using SPSS version 21.

Results: 532 patients were analyzed under intention to treat principle using last observation carry forward method. Mean CBS score reduced from 29.86±4.5 at baseline to 12.33±7.6 at completion of 2 years. Repeated measures ANOVA, at time points 0 (baseline), 3, 6, 9, 12 , 15, 18, 21 and 24 months, showed significant reduction in CBS scores [Wilk’s Lambda 0.104, F=564, df 524; p=00001]. The FEV1 and FEV1/FVC was maintained within normal limits. 86% prescriptions included Lycopodium, Arsenicum album, Pulsatilla, Phosphorus, Stannum metallicum, Calcarea carbonica, Silicea, Bryonia alba.

Conclusion: The result suggests effectiveness of homoeopathic treatment in early stage of SCMB patients. However, controlled trials are required for further validation.
Outcomes and effects of homeopathic treatment of malaria in Kenya, a multi-centre study
Authors: Brands Martien , Van Berkel Suzanne , Wambua Julius
Published: April 2021

Abstract.

In Kenya malaria is the leading cause for illness and death; homeopathy is used for many years to treat this disease. A previous study in Ghana in 1996, showed comparable effects of homeopathy and chloroquine. Methods: In three studies we documented homeopathic treatment in a retrospective qualitative study, a prospective single arm study, and a comparison between one cohort receiving homeopathic treatment and the other artemether. Results: In the qualitative retrospective study (2014) (n=54), we related typical malaria and individual symptoms, with remedy prescriptions and affected organs. Principal Component Analysis (PCA) showed, that specific remedies were prescribed for patterns of affected organs . In the prospective study (2014) (n=70), the primary outcome was the parasitological status at the first follow up (median 8 days), secondary outcome was the quality of life measure with Outcome Related to Impact on Daily Life.

In the third study, of the group (n=79) (b) exposed to homeopathy, n=6 (a) were still parasite-positive after one week, in the control (co-artem) group of n=35 (c) no patient was positive (d). The odds ratio was 5.8068 (95% CI 0.3183 – 105.8794), with z = 1.187 and P = 0.2352. The difference was not statistically significant; homeopathic remedies and coartem tablets had similar effect for uncomplicated malaria in that region. Co-morbidity was treated with different remedies.

Conclusion: Homeopathic treatment can be used as a valuable option, also when other treatments are ineffective by microbial resistance, not indicated (as in pregnancy) and financially not affordable.

Key words: malaria, homeopathy, artemether, comparative study, cohort study, plasmodium, ORIDL
Extreme dilutions of mercuric chloride produce longer binding interaction with ?-amylase as compared to blank solvents
Authors: Mondal Priya , Chakraborty Indrani , Sukul Nirmal Chandra , Konar Atheni , Sarkar Tandra , Sukul Anirban
Published: April 2021

Background

High and ultra low doses of HgCl2 modulate ?-amylase starch interaction through two different binding sites of the enzyme. Mercurius corrosivus at ultra high dilution (UHD) is reported to have a long duration of action for 30-60 days.

Objectives

(i) To see whether the mother tincture and UHDs of mercuric chloride could directly act on ?-amylase without intervention of its substrate starch. (ii) To see whether the MT and UHDs produce longer binding interaction with ?-amylase than the control.

Methods

Mercuric chloride MT (0.15 M) or Merc cor ? and its three UHDs, 30, 200, 1000 cH called potencies were in 90% ethanol. Blank 90% ethanol and deionised and distilled (DD) water were used as controls. All ethanol based ligands were diluted with DD water to reduce EtOH content to 0.09%. Using an ITC instrument each ligand was injected once at 10 µl into15µM ?-amylase at 25 0C and the reaction was observed for 2000 s.

Results

While Merc cor ? produced endothermic reaction, all other ligands did exothermic reaction. Water control and blank ethanol maintained post injection heat change up to 1200 sec. All other ligands sustained heat change for the entire period of observation (2000 sec).

Conclusions

Merc cor ? and potencies produced exactly the opposite reaction at the protein binding sites. The reaction was short-lived with water control and blank ethanol, but prolonged with Merc cor ? and potencies. Merc cor 200 cH and 1000 cH produced highest heat change (6 µl/sec) during interaction with ?-amylase.
The Supreme Court's Two Constitutions: A First Look at the "Reverse Polarity" Cases
Authors: Hellman Arthur D.
Published: April 2021

N/A
ANALISIS KESESUAIAN PENGGUNAAN LAHAN TERHADAP POLA RUANG DI DAERAH ALIRAN SUNGAI BIALO
Authors: Soma Andang Suryana
Published: April 2021

This research aims to analyze the land use and identify the suitability of the land use plan of space in Bialo Watersheds and determine the direction of land use if there is a mismatch between the land use with the regional plan in Bialo watersheds. The data were collected in primary data was the land use  and secondary data of regional plan. The data were analyzed with interpretation, test accuracy, and conformity determination for land use overlay with the plan space. Based on the analysis of land-use suitability with the plan space, a land-use plan is acquired that fits the area of 87.80% and is not following 12.20%. Use of the referral in the form of reboisation, the village forests, agroforestry, multi-purpose tree species (MPTS) on dry land forest land use, agricultural secondary dry land, settlements. Planting cover crops and soil reinforcement terrace on paddy fields and natural succession on land use scrub.
PRODUKSI BIBIT KAKAO (Theobroma cacao L) DENGAN PEMANFAATAN AGEN HAYATI JAMUR TRICHODERMA SP.
Authors: Amiruddin Leli
Published: April 2021

Bibit  kakao yang berkualitas diperoleh melalui pemeliharaan yang baik dengan penggunaan jamur yang bermanfaat mengoptimalkan fungsi media tanam yang mengandung bahan organik. Salah satu diantaranya adalah penggunaan jamur Trichoderma sp. Pemanfaatan Jamur Trichoderma sp. memacu pertumbuhan bibit tanaman kakao. Penelitian bertujuan untuk melihat pengaruh pemberian jamur Trichoderma sp. pada pertumbuhan bibit tanaman kakao. Terdapat dua perlakuan  yaitu: pemberian jamur Trichoderma sp. 20 mg/polybag dan tanpa pemberian jamur Trichoderma sp., yang masing-masing terdiri atas 12 unit poercobaan. Data dianalisis dengan statistic sederhana. Hasil percobaan menunjukkan bahwa pemberian jamur Trichoderma sp. 20 mg/polybag memberikan pengaruh terbaik dan hasil tertinggi pada bibit tanaman kakao pada semua parameter yang diamati.
اتجاهات المواطنين نحو المسؤولية المجتمعية للقطاع الخاص الفلسطيني في ظل جائحة كورونا
Authors: عصام الأطرش
Published: April 2021

هدفت هذه الدراسة التعرف على اتجاهات المواطنين نحو المسؤولية المجتمعية للقطاع الخاص الفلسطيني في ظل جائحة كورونا، كما هدفت الدراسة التعرف على معززات المسؤولية المجتمعية ومعوقاتها ونماذجها في ظل جائحة كورونا، وقد استخدم الباحث المنهج الوصفي في دراسته، وقد تمثل مجتمع الدراسة بجميع المواطنين في الضفة الغربية، كما تمثلت عينة الدراسة ب (455) مواطناً تم اختيارهم بطريقة العينة المتيسرة، كما تمثلت أداة الدراسة باستبانة تم تصميمها لغايات جمع البيانات والمعلومات، وقد توصلت الدراسة إلى مجموعة من الاستنتاجات أبرزها عدم رضا المواطنين عن المسؤولية المجتمعية للقطاع الخاص في ظل جائحة كورونا، وعدم رضا المواطنين عن صندوق وقفة عز، وقد أوصت الدراسة بمجموعة من التوصيات أبرزها، ضرورة إجراء تعديل قانوني على قانون الشركات يلزم الشركات بالمسؤولية المجتمعية بنسبة تصل إلى (5%) من أرباحها.
Condition monitoring of Electrical Submersible Pumps (Faults review)
Authors: Al-Hashmi Salem. A.
Published: April 2021

This paper is a part of condition monitoring of electrical submersible pumps (ESP). It assigned for reviewing and discussing faults or malfunctions of this kind of pumps. Therefore, it reviews all-important information related to this machine such as construction and operation. It focuses specifically on faults and details of these types of fault. Although there are slight differences between building submersible pumps in terms of the different technologies that different manufacturers use in making this type of pump, all kinds of these types of pumps are almost the same. In this context, pumps faults were reviewed based on major and common failures of this type of pumps.
Evaluating the performance of teaching staff members, a step towards teaching performance development of higher education in Sebha University
Authors: Mare Zamzam Amhimmid
Published: April 2021

This study aims to show the importance of evaluating the teaching performance level of the University teaching members. It also aims to provide the suggested mechanisms for evaluating the teaching performance of the teaching staff members of Sebha University. This study was based mainly on documents and analytic description to collect information about the importance and ways of evaluating teachers with reference to some of the international experiences on teaching performance development. This study concluded that the absence of an experienced entity that would develop the teaching performance of faculty members is one of the main reasons for the weak teaching performance at Sebha University. Based on the results of the study, it is recommended that there should be a planned system based on measured standards and criteria for evaluating staff members to improve the quality of teaching in the higher education domain.
Dietary Habits, Perceptions and Barriers Among Government and Private College Intermediate Students in Karachi: A Cross-Sectional Survey
Authors: Rashid Mariam , Noor Sabeela , Salam Khadija Abdus , Irfan Ramsha , Siddique Ayesha
Published: April 2021

Objective: To determine differences in eating practices, perceptions, and perceived barriers among intermediate students of government and private sectors in Karachi. Study design and setting: A cross-sectional study was conducted in six intermediate colleges of Karachi from October to December 2018. Methodology: Total N=390 students aged 16-24 years were selected via non-probability convenience sampling. The study team developed a questionnaire to assess the dietary habits and barriers among the students. Results: Mean BMI of government college students was 20.41 ± 4.15 kg/m2 while that of private college students was 22.25 ± 5.43 kg/m2. The proportion of underweight participants was higher (36.8%) in government college students, and overweight students being higher in private (23.8%). Similar responses were recorded for daily meals and weekly fastfood and fruit consumption. Skipping meals was found out to be a common practice among students. Breakfast was most commonly skipped meal among both groups (23.9% & 39.2%, respectively). Watching television during meals was common in both groups (58.7% & 67.7% respectively). The majority of the students from both groups did not familiar with the term body mass index BMI (84.6% & 82.5%, respectively). Smoking was more common among the private sector, 16.9%, compared to 3.5 % of the government sector. Fruit juice was considered a healthier option (58.7% & 52.9%, respectively). Similarly, white bread against bran bread was perceived healthier by the majority in both groups (70.1% & 59.3%, respectively). Carbohydrate was reported as a major nutrient in the diet by (51.7% & 57.1% respectively). Factors like educational stress, time, will-power to maintain the diet, availability of junk food, and climate were some of the significant influencers of diet/lifestyle recorded. Conclusion: Students from both groups shared similar eating and lifestyle practices irrespective of their educational institutes’ status.
Reliability of Sprint Force-Velocity-Power Profiles Obtained with KiSprint System
Authors: Šarabon Nejc , Kozinc Žiga , Ramos Amador Garcia , Knežević Olivera M. , Čoh Milan , Mirkov Dragan M.
Published: April 2021

This study aimed to assess the within- and between-session reliability of the KiSprint system for determining force-velocity-power (FVP) profiling during sprint running. Thirty (23 males, 7 females; 18.7 ± 2.6 years;) young high-level sprinters performed maximal effort sprints in two sessions separated by one week. Split times (5, 10, 20 and 30 m), which were recorded with a laser distance meter (a component of the KiSprint system), were used to determine the horizontal FVP profile using the Samozino’s field-based method. This method assesses the FVP relationships through estimates of the step-averaged ground reaction forces in sagittal plane during sprint acceleration using only anthropometric and spatiotemporal (split times) data. We also calculated the maximal theoretical power, force and velocity capabilities and the slope of the FV relationship, the maximal ratio of horizontal-to-resultant force (RF), and the decrease in the RF (DRF). Overall, the results showed moderate or good to excellent within- and between-session reliability for all variables (ICC > 0.75; CV < 10 %), with the exception of FV slope and DRF that showed low relative reliability (ICC = 0.47-0.48 within session, 0.31-0.33 between-session) and unacceptable between-session absolute reliability values (CV = 10.9-11.1 %). Future studies are needed to optimize the protocol in order to maximize the reliability of the FVP variables, especially when practitioners are interested in the FV slope and DRF. In summary, our results question the utility of the sprint-based FVP profiling for individualized training prescription, since the reliability of the FV slope and D RF variables is highly questionable.
Immunotherapy and prevention of breast cancer
Authors: Thacker Neelam , Taneja Perianayagam
Published: April 2021

Breast cancer is the most commonly diagnosed cancer in women and is a leading cause of cancer death in women worldwide. Despite the significant benefit of the use of conventional chemotherapy and monoclonal antibodies in the prognosis of breast cancer patients and although the recent approval of the anti-PD-L1 antibody atezolizumab in combination with chemotherapy has been a milestone for the treatment of patients with metastatic triple-negative breast cancer, immunologic treatment of breast tumors remains a great challenge. In this review, we summarize current breast cancer classification and standard of care, the main obstacles that hinder the success of immunotherapies in breast cancer patients, as well as different approaches that could be useful to enhance the response of breast tumors to immunotherapies.
Determinant Faktor Keberhasilan Toilet Training Pada Anak Toddler Di Rw 002 Perumahan Sinar Pamulang, Tangerang Selatan
Authors: Pratiwi Rita Dwi
Published: April 2021

Toilet training is an attempt to train children to be able to control bowel movement (BAB) or urinate (BAK). Toilet training can be done in the child's independence phase, which usually begins at the age of 18-36 months. The objective of this research was to recognize whether there is any correlation between the level of knowledge of mothers just given counseling, on her attitude in the implementation of the toilet training and keep participating actively in toilet training on all children aged 18 -36 months in 002 Hamlet, the Sinar Pamulang Housing Regency, South Tangerang. This study used a quantitative method. It used children to commit an analytic design with the cross-sectional approach, the number of the sample was 61 significant proportion of respondents, with a purposive sampling method, and used a questionnaire to prove data collection. The result of this research obtained there was a correlation knowledge of mothers with their attitude about toilet training (p value 0,000), knowledge of mothers for the implementation of the toilet training (p value 0,000), knowledge of mothers for the success of toilet training (p value 0,002), attitudes of the mother with the implementation of the toilet training (p value 0,017), attitudes of the mothers with the success of toilet training (p value 0,004), consistency of participating actively in the implementation of the toilet training (p value 0,000). The fit and proper test of logistic regression showed that the dependent variable for which the most influence to successful toilet training is the implementation of the mother toilet training (p value 0,011) with a value of up (persons of very = 5,73). The results of this study can be a consideration for educational institutions, especially for students in the effort to optimize the growth of children by disseminating information about mother's knowledge, mother's attitudes, implementation, and success of toilet training.
Evaluasi Penggunaan Obat Sitostatika Ditinjau Dari Berbagai Literatur
Authors: Ismaya Nurwulan Adi , Andriati Riris , Ratnaningtyas Tri Okta , Hasanah Nur , Yulianti Dewi
Published: April 2021

Cancer is a non-communicable disease, or NCD (Noncommunicable diseases). It becomes a second causative factor of mortality in global. In some cases and scientific journals that show a high problem of drug use in cancer patients. The purpose of this research is to identify the use of sitostatica drugs which are reviewed from a variety of literature. This study uses literature study research. Literature study is a research conducted by researchers by collecting a number of library data relating to the problem and research objectives. Result showed there are the most inaccurate drug diagnosis criteria for patients are 16 cases (22.86%). Inaccuracy in most doses is 21 cases (29.18%). the most inaccurate dose inaccuracy is 127 cases (36.38%), inaccurate indications include the need to add drugs the most is 26 cases (25.49%), drugs without the most indications are 11 cases (10.78%) , inaccurate duration of administration of the most drugs is 15 cases (23.43%), the criteria for alerting for the most side effects are 208 cases (59.59%) the right criteria for the administration method is 100%, the patient is 100% right, and the right submission (dispensing) and information at 100%.
Sistema de parques e corredores verdes de Raleigh, Carolina do Norte, EUA: um parque com a Cidade Dentro
Authors: Pippi Luis Guilherme Aita , Angeoletto Fabio
Published: April 2021

This paper proposes to analyze the effectiveness of the Plan for the medium-sized city of Raleigh, North Carolina, USA through its planning and design of a system of Parks and Green Corridors as an example to be followed by contemporary cities, in relation to the planning and connectivity of its open space system, represented by parks, recreational areas and green corridors. In this sense, the quality of urban life of its inhabitants, free spaces, and perpetuity of the natural resources of the city of Raleigh is directly related to the opportunity of the realization of the first American plan of the network of green corridors to a capital, "A Park with a City within ", as a way to contain urban growth, minimize anthropic impacts and promote the increase of leisure and recreation areas in all areas of the city, as well as their connectivity and functionality. The effectiveness of the constitution of this integrated system, consisting of the network of green corridors, is based on the implementation and constitution of the whole plan, over a period of several years, through the outline of its characteristics, objectives, and functions. Discussions, premises, and strategies for planning, project renovation of existing structures of the park system and green corridors.
Baukunst and Zeitwille between Europe and America
Authors: Tostões Ana , Ferreira Zara
Published: April 2021

Mies enjoyed great prominence in Europe and America. Starting in Europe, his first incursions resulted in the German Pavilion for the Barcelona International Exhibition (1929), the Tugendhat House (1930) and the Krefeld silk factory and houses. The Illinois Institute of Technology (1943-1957), the Lake Shore Drive (1951), the Farnsworth House (1951), the Seagram building (1958) and the Toronto-Dominion Centre (1969), bear witness to his work in North America. Back in Berlin, The Neue Nationalgalerie (1968) testifies to the sublime and perfect achievement of his path towards Baukunst and Zeitwille. These ideas, which one may translate, respectively, as the art of building and the will of the time, are anchored in the Mies’s belief that architecture should be metaphysically charged with creative life force. This led him to the modern achievement of developing a new kind of freedom of movement in space, following his sense of order and his very unique conception of urban space.
The Heritage of Mies
Authors: Hanenberg Norbert , Lohmann Daniel , Raabe Christian
Published: April 2021

Mies van der Rohe’s built work covers a timeframe of over 60 years, including two world wars and several revolutionary events in the history of architecture. The extraordinary architect has influenced 20th century architecture worldwide like few others have. In the context of several restoration projects, the time has come to review the condition of his buildings: Is their materiality as timeless as their appearance? Did his constructions, which are of sometimes an experimental nature, prove to be sustainable, or did they fall into disrepair? How can Mies van der Rohe buildings be documented, repaired, restored, reconstructed, without losing the characteristic details of his work, and in order to preserve the architectural integrity and relevance of the Mies van der Rohe's oeuvre?
Chryseobacterium indologenes as a Rare Pathogen of Bacteremia in Febrile Neutropenia
Authors: Demir Gündoğan Begümhan , Sagcan Fatih , Çıtak Elvan Çağlar
Published: April 2021

Chryseobacterium indologenes (C. indologenes) is nonmotile, oxidase-, and indole-positive gram-negative aerobic bacillus. Immunosuppression, comorbidities, use of broad-spectrum antibiotics are known risk factors for C. indologenes-related infections. We report a neutropenic fever caused by C. indologenes in a 16-month-old boy who was treated due to the neuroblastoma. According to the antimicrobial susceptibility test result, he was treated with cephaperazone/sulbactam.
2D MODEL NUMERIC AMR, MODELLING AND SIMULATION OF MAGNETOCALORIC EFFECT
Authors:   “Gheorghe Asachi” Technical University of Iasi, Botoc Dorin
Published: April 2021

In this article, the study of gadolinium material is focused on determining the constants and properties of the material, the analysis of substructures and the orientation of dipole moments. Research into material aspects provides important information on atomic-level sub-phenomena in the field of the main magnetocaloric phenomena for the magnetic refrigeration regenerator (AMR). The experimental study is mainly based on testing the magneto-caloric material with different magnetization equipment, developed to measure more precise and fine details, magnetic refrigerator, AMR prototype development and the like. The method used uses differential equations. For both cases, where the loads are relatively simple and for more complex cases, the method can be easily applied.
QUANTUM COMPUTING
Authors:   Swiss Technology Association, Electronics Group Switzerland, Băjenescu Titu-Marius I.
Published: April 2021

The quantum computer, is a "supercomputer" that relies on the phenomena of quantum mechanics to perform operations on data. Object of suppositions, sometimes farfetched, quantum mechanics gave birth to the quantum computer, a machine capable of processing data tens of millions of times faster than a conventional computer. A quantum computer doesn't use the same memory as a conventional computer. Rather than a sequence of 0 and 1, it works with qubits or quantum bits. The quantum computer is a combination of two major scientific fields: quantum mechanics and computer science. Quantum mechanics, on which this computer is based, governs the movement of bodies in the atomic, molecular and corpuscular domains, is a theory whose logic is totally contrary to intuition and it is essential to use mathematics to fully grasp it. Quantum computing is the sub-domain of computer science that deals with quantum computers using quantum mechanical phenomena, as opposed to those of electricity exclusively, for so-called "classical" computing. The quantum phenomena used are quantum entanglement and superposition. The article examines some aspects related to the development, operation, advantages and difficulties, applications and future of the quantum computer.
ENERGY-SAVING CHAMBER IN PRODUCTION OF BUILDING MATERIALS AND PRODUCTS
Authors:   Odesa State Academy of Civil Engineering and Architecture, Zavoloka Michael , Shinkevich Elena ,   Odesa State Academy of Civil Engineering and Architecture, Vinnichenko Varvara ,   Kharkiv National University of Civil Engineering and Architecture, Plit Alexander ,   Odesa State Academy of Civil Engineering and Architecture
Published: April 2021

This paper presents the results of a study of the compressive strength of concrete in a cyclic solar chamber. The analysis of the existing types of industrial solar chambers is carried out and the main structural elements are considered. The method of calculating the solar chamber for the production of concrete products is presented. Experiments were carried out on heavy concrete compositions using MC-Bauchemie superplasticizers additives: MC-PowerFlow 3100 and MC-PowerFlow 2695. The samples were kept in a cyclical solar chamber. The strength of concrete was determined at different periods of concrete hardening. A comparative analysis of the results of the compressive strength of concrete in a solar and normal hardening chamber is carried out.
EFFICIENCY OF COAGULATION-FLOCCULATION PROCESS IN THE TREATMENT OF ABATTOIR EFFLUENT
Authors:   Department of Civil Engineering, Federal University of Agriculture, Familusi Ayokunle , Adekunle Adebola ,   Department of Civil Engineering, Federal University of Agriculture, Badejo Adedayo ,   Department of Civil Engineering, Federal University of Agriculture, Adeosun Olayemi ,   Department of Agricultural and Bio-Systems Engineering, Federal University of Agriculture
Published: April 2021

The use of coagulation-flocculation process as means of wastewater treatment is gradually becoming more popular. This research work is to evaluate the efficiency of coagulation-flocculation process in the treatment of abattoir effluent. Samples of abattoir effluent were collected from a slaughterhouse at Ede, Nigeria, and Alum was used in the coagulation-flocculation treatment of the effluent. The physico-chemical and bacteriological analyses of the untreated and treated effluent were carried out and these were used in determining the efficiency of the treatment process. The values obtained (from the physico-chemical and bacteriological analyses) were also compared with the effluent standard of Environmental Protection Agency (EPA). Coagulation-flocculation process is performed efficiently in reducing the contaminant level of Colour, TDS, Turbidity, Conductivity, TSS, Total Hardness, COD, Coliform, metals and other pollutants from the effluent.
Stroke in the Brain Scanner at Kinshasa University Clinics and Marie Biamba Mutombo Hospital: A Case Series Study
Authors: Samuel Mbaki Bula , Aliocha Nkodila Natuhoyila , Michel Lelo Tshikwela
Published: April 2021

Background and objective: Strokes represent a significant cause of morbidity and mortality throughout the world. But data relating to this in sub-Saharan Africa is scarce. The objective of this study is to identify traumatic pathologies with CT scan in patients followed in hospitals in Kinshasa, Democratic Republic of Congo.
Methods: descriptive cross-sectional study of data from the medical records of patients having performed a cerebral CT scan covering a period of 24 months at the University Clinics of Kinshasa and at the Biamba Marie Mutombo Hospital. The study parameters are of three kinds, those relating to socio-demographic data (age, sex, date of the CT scan); those relating to the clinical data and the indications for the examination and the CT data.
Results: Among the 717 cases of stroke diagnosed by CT scan, 529 were of the ischemic type while 188 were of the hemorrhagic type (Figure 1). The ischemic stroke / hemorrhagic stroke ratio was 3/1. The demographic transition was very characteristic for all strokes increasing with advancing age 18.4% in the age 0-19 years, 14% in the age group 20-49 years, 27.8%, and 56.6% in age ≥ 60 years. Comparisons of the proportions of ischemic and hemorrhagic strokes by sex and age groups. There was no statistically significant difference in the sex of patients between the types of stroke (P> 0.05) when there was a statistically significant difference in the proportions of hemorrhagic and ischemic strokes between age groups. There was therefore an exponential type curve of the proportions of ischemic-type strokes according to age advancement: the highest frequency at age ≥ 60 years.
Conclusion: strokes are frequent in Kinshasa; they are characterized by a high frequency of ischemic stroke and increase with age.

Key words: Stroke, CT scan, Epidemiological transition hospitals in Kinshasa.
THE ROLE OF MOTIVATIONAL INTERVIEWING TECHNIQUES IN OVERCOMING INTERFERENCE PECANDU DRUGS AT AR-RAHMAN DRUG REHABILITATION PANTI AR-RAHMAN PLAJU DARAT PALEMBANG
Authors: Noviza Neni
Published: April 2021

One of the problems experienced by drug addicts is the loss of confidence due to the effects of  consuming drugs. To overcome this one of the techniques used dip re-rehabilitation of Ar rahman drugs is to use motivational interviewing techniques. This technique aims to provide  motivation for addicts to change. This study aims to determine the confidence of drug addicts  when they enter the rehabilitation of drugs Ar-Rahman, to know the process of motivational  techniques Interviewing (MI) in Arrangman Drug Rehabilitation and to know the role from  motivational interviewing (MI) techniques. The type of data used is qualitative data. The  subjects of this study amounted to 3 people drug addicts, and 1 counselor. Sources of data  taken in this study are primary and secondary data sources. Data obtained by using interview  methods, observation methods and documentation methods. Data analysis techniques of  qualitative data analysis consists of four stages, namely: data reduction (data reduction),  presentation data (display data), conclusion drawing and verification. From the research results  obtained confidence drug addicts when new re-entry rehabilitation Ar-Rahman drugs that is,  often solitary, be closed to others, silent, embarrassed, insecure and always negative thingking  (thinking negative) to others, fear, to himself, always be negative, no matter to the  environment, reluctant to communicate, not serious, irresponsible, closed and pessimistic  about what he does. The process of motivational interviewing (MI) technique carried out by the  counselor at Ar-Rahman drug rehabilitation center and the four principles is run, expressing  empathy, developing discrepancy, accepting resistance and supporting efficacy. Motivational  Interviewing Technique (MI) is very instrumental in overcoming the confidence of drug addicts  with the change of attitude behavior and way of thinking, the changes experienced are, the  client is more serious, responsible, think and be positive, open to others, optimistic, thinking  that is rational, and better understand the feelings of self and others.
ANALYSIS OF CRIMINOGEN DETERMINANTS IN CHILDREN CLIENTS
Authors: Hanifah Rizki Ayu
Published: April 2021

This study aims to describe the influence between the level of social bonding on child mischief on child clients in Probation Boards Class I Bandung. The type of research is descriptive to describe and explain the influence of social bonding level to child mischief on child client in Probation Boards Class I Bandung. The test is done by measuring the dimension of social bonding as stated by Hirschi, that is Attachment, Commitment, Involvment, and Belief. This study uses a quantitative approach. This study describes the influence of social bonding level on child mischief on child clients in Probation Boards. The sampling process of the researh was done by total sampling technique. After sampling, we get 501 Litmas documents of children. Data collection was done by several techniques, namely content analysis, and literature study. Management of data obtained from the content analysis, and literature study. Management of data obtained from the contents of litmas that have been inserted into the coding is done by using SPSS 20 program. Based on the results of research that has been done by the author for 3 weeks at Probation, that the level of social bonding on child clients in Probation is at a low level. So it can be concluded that social bonding affects children do misbehavior. Therefore, to create social bonding in children, it is necessary to improve the pattern ofcare in the family, and supervision both in school and community environment.
RELATIONS OF IMPROVEMENT OF DRUG USERS AND THE AVAILABILITY OF MEDICAL PERSONS WITH HIV / AIDS IN Correctional Institutions
Authors: Butar Butar Herry Fernandes , Hamzah Imaduddin
Published: April 2021

The change of health paradigm on the world causing policy’s transformation and public concern regarding enhancement on Indonesian health rate rating. Medical problem happens in every line of social life, especially at Correctional Institutions and Correctional Detention Center as the place for criminals. Narcotics as one of the biggest problems in Correctional Sub-organizations are still one of the biggest contributors on overcrowded prison situations. This research intends to describe correlation between drug users and prisoners with HIV in prison. Methods being used are statistic correlative with qualitative approach which data obtained from Correctional Database System. Those data are narcotics users and prisoners with HIV in Correctional Suborganizations at 33 Ministry of Law and Human Rights Region Office. It can be concluded that the correlation between two variables is moderate relation.
Size and Operating Profitability Portfolio Returns and Return Premia in Japan—A Tour d’horizon
Authors: Tsuji Chikashi
Published: April 2021

This study examines the Japanese equity returns and return premia by focusing on firm size- and corporate operating profitability-sorted portfolios over the period from 1990 to 2020. As a result of our explorations, this study derives the following much beneficial findings. (1) The effects of corporate operating profitability and firm size are generally continuously seen in the Japanese equity market. More specifically, (2) the size effect is much stronger in our latter half sub-period; while the operating profitability effect is similarly seen in both our former half and latter half sub-periods. Furthermore, (3) we stress that this study employs the data in US dollars, and calculates several key statistics and measures for not only our full sample period but also many different sub-periods, in which economic and business circumstances are much different. Therefore, for both Japanese and international equity investors, our findings shall be highly useful for enriching and furthering the understanding of returns and return premia of Japanese equity portfolios.
Proximity and Animal Ethics in “The Last Will and Testament of Silverdene Emblem O'Neill”
Authors: Williams Sebastian
Published: April 2021

“The Last Will and Testament” portrays the proximity of Eugene O'Neill and his dog, Blemie, questioning the ethical obligations that humans have toward domestic animals. Building on animal studies, I demonstrate that the style of “The Last Will and Testament” shapes the narrative's ethics by treating Blemie as a being in himself. This article compares animal representations in “The Last Will and Testament” and The Hairy Ape, and it shows that the genre of the “will and testament” raises questions about animal communication, desire, and suffering. The article concludes by emphasizing that although “The Last Will and Testament” foregrounds the emotional reciprocity of pet-owner relationships, it can also obfuscate the long history of animal domination.