bluuebunny/crossref_metadata_2025 huggingface dataset:
Assist-linked brief intervention to reduce risky pattern of substance use in male workers employed at a tertiary care hospital in India: A randomized controlled trial
Authors: Prasad Sambhu , Basu Debasish , Mattoo Surendra K. , Subodh B. N
Published: January 2023

Background:

Substance use in workplace leads to adverse effects both on the employees and on the workplace. Existing research focuses on alcohol-related harm, while workplace use of other substances has been neglected. There are no randomized controlled studies of brief interventions in Indian hospital settings.

Aim:

To evaluate the efficacy of World Health Organization (WHO) alcohol, smoking, and substance involvement screening test (ASSIST)-linked brief intervention (ALBI) for reducing risky patterns of substance use in male workers at a tertiary-care hospital in North India.

Material and Methods:

The study was conducted in two phases. In Phase-I, a random list of 400 employees was generated from the entire pool of male hospital workers, of which 360 participated. Data on the ASSIST risk categories (mild, moderate, and high) were generated from Phase I. In Phase-II, moderate- or high-risk subjects (‘ASSIST screen-positive’) were randomized into intervention and control groups, with 35 screen-positive subjects in each group. The intervention group was provided a 15–30-min structured session per ALBI protocol, while the control group was given a 15–30-min general talk on health-related consequences associated with substance use. The subjects were compared on ASSIST score, WHO quality-of-life brief version (WHOQOL-BREF) and readiness to change questionnaire (RCQ) at baseline and at 3-month follow up.

Results:

The prevalence of moderate-to-high-risk use of tobacco, alcohol, and cannabis in the total sample was 28.6%, 27.5%, and 6.9%, respectively. At 3-months postintervention follow-up of the randomized sample, recipients of ALBI had significant reduction of ASSIST scores for all substances compared to the control group (p < 0.001). More participants receiving ALBI were ready to change to RCQ action stage (p values for tobacco, alcohol, and cannabis <0.001, <0.001 and 0.007, respectively). WHOQOL-BREF scores significantly improved in ALBI group across all domains.

Conclusion:

ALBI was effective in reducing risky substance use, increasing readiness to change and improving the QOL of the subjects at workplace setting.
Relationship between serum lipids and depression: A cross sectional survey among adults in Haryana, India
Authors: Mulchandani Rubina , Lyngdoh Tanica , Nangia Ria , Singh Sukriti , Grover Sandeep , Thakur JS
Published: January 2023

Introduction:

Dyslipidemia and mental illnesses are significant contributors to the global noncommunicable disease burden and studies suggest an association between them.

Aim:

Using data from a noncommunicable disease risk factor survey conducted in Haryana, India, we undertook a secondary data analysis to examine the association between lipids and depressive symptoms.

Methods:

The survey involved 5,078 participants and followed the World Health Organisation STEPwise approach to NCD risk factor surveillance approach. Biochemical assessments were undertaken in a subset of participants. Lipid markers were measured using wet chemistry methods. Depressive symptoms were assessed using the Patient Health Questionnaire–9. Descriptive statistics were presented for all variables; logistic regression was used for association analyses.

Results:

The mean age of the study population was 38 years and 55% of them were females. A majority of the participants belonged to a rural background. The mean total cholesterol was 176 mg/dL and approximately 5% of the participants were found to have moderate to severe depression. The association of total cholesterol (odds ratio [OR] 0.99, P = 0.84), LDL-cholesterol (OR = 1.00, P = 0.19), HDL-cholesterol (OR = 0.99, P = .76), and triglycerides (OR 1.00, P = .12) with depressive symptoms was not significant.

Conclusion:

This study did not find any association between lipids and depressive symptoms. However, further investigations using prospective designs are warranted to understand this relationship and complex interactions with other mediating factors better.
Analysis of risk factors related to acute radiation dermatitis in breast cancer patients during radiotherapy
Authors: Liu Di , Zheng Zhewen , Zhang Shuyuan , Zhu Chunmei , Zhang Hongyan , Zhou Yunfeng
Published: January 2023

Aims:

To investigate the incidence and influencing factors of acute radiation dermatitis (ARD) induced by radiotherapy in postoperative patients with breast cancer.

Methods and Materials:

A retrospective analysis was conducted on 598 patients with breast cancer who received postoperative radiotherapy from November 18, 2014 to September 14, 2019. The radiotherapy technology included two-dimensional radiotherapy, three-dimensional conformal radiotherapy, intensity-modulated radiotherapy, and tomotherapy. The occurrence of ARD in patients was then followed up and recorded. The independent risk factors for radiation-induced dermatitis were analyzed by using an orderly logistic regression model.

Results:

Of the 598 patients, 431 had mild skin reactions, including pigmentation and dry desquamation (grade 1), 151 developed wet desquamation and tender erythema (grade 2), and 16 had severe skin reactions, including flaky wet scaling and erosion (grade 3). There were no grade 4 skin reactions. The severity of ARD was independent of the following factors: Age, diabetes, allergy, quadrant, pathological type, the clinical stage, the tumor stage, triple-negative breast cancer, ki-67 expression, adjuvant chemotherapy, endocrine therapy, targeted therapy, radiotherapy area, and boost irradiation. However, it was found to be dependent on the body mass index, surgery type, radiotherapy technique, node stage, and the prophylactic use of topical agents.

Conclusions:

ARD in response to postoperative radiotherapy in patients with breast cancer is common and mild. Clinicians and patients need to cultivate awareness of the potential risk factors involved and then intervene to alleviate skin reactions and improve the quality of life.
CASP4 and CASP8 as newly defined autophagy-pyroptosis-related genes associated with clinical and prognostic features of renal cell carcinoma
Authors: Li Tao , Liu Ning , Zhang Guangyuan , Chen Ming
Published: January 2023

Objective:

The rapid discoveries of autophagy and pyroptosis have opened new avenues for treating renal cell carcinoma (RCC). The objective was to identify potential autophagy-pyroptosis-related drug targets and plausible prognostic biomarkers crucial for disease detection.

Materials and Methods:

Gene expression data were downloaded from Gene Expression Omnibus (GSE168845), and autophagy-pyroptosis-related differentially expressed genes (DEGs) were identified. The prognostic values of DEGs were assessed using differential expression analysis and Kaplan–Meier curves, a prognostic nomogram was constructed using the DEG data, and the correlation between DEGs and infiltrating immune cells was evaluated. Additionally, quantitative real-time polymerase chain reaction (qRT-PCR) and immunohistochemistry (IHC) were carried out to verify the expression levels of DEGs.

Results:

CASP4 and CASP8 were identified as RCC-associated autophagy-pyroptosis-related genes, and CASP4 and CASP8 were found to be highly expressed in RCC tumor tissues. High expression of CASP4 and CASP8 was associated with higher pathological staging and poorer prognosis, whereas a prognostic nomogram constructed based on CASP4 and CASP8 could better predict RCC patient survival rates. Additionally, increased expression of CASP4 and CASP8 was highly correlated with the expression levels of multiple infiltrating immune cell types. Moreover, qRT-PCR and IHC validated the increased expression of CASP4 and CASP8 in RCC.

Conclusion:

CASP4 and CASP8 were autophagy-pyroptosis-related genes associated with immunotherapy in RCC. CASP4 and CASP8 were identified as potential targets and effective prognostic biomarkers for RCC.
Serological indices and ultrasound variables in predicting the staging of hepatitis B liver fibrosis
Authors: Xie Daolin , Ying Minghua , Lian Jingru , Li Xin , Liu Fangyi , Yu Xiaoling , Ni Caifang
Published: January 2023

Objective:

To compare the diagnostic efficacy of serological indices and ultrasound (US) variables in hepatitis B virus (HBV) liver fibrosis staging using random forest algorithm (RFA) and traditional methods.

Methods:

The demographic and serological indices and US variables of patients with HBV liver fibrosis were retrospectively collected and divided into serology group, US group, and serology + US group according to the research content. RFA was used for training and validation. The diagnostic efficacy was compared to logistic regression analysis (LRA) and APRI and FIB-4 indices.

Results:

For the serology group, the diagnostic performance of RFA was significantly higher than that of APRI and FIB-4 indices. The diagnostic accuracy of RFA in the four classifications (S0S1/S2/S3/S4) of the hepatic fibrosis stage was 79.17%. The diagnostic accuracy for significant fibrosis (≥S2), advanced fibrosis (≥S3), and cirrhosis (S4) was 87.99%, 90.69%, and 92.40%, respectively. The area under the curve (AUC) values were 0.945, 0.959, and 0.951, respectively. For the US group, there was no significant difference in diagnostic performance between RFA and LRA. The diagnostic performance of RFA in the serology + US group was significantly better than that of LRA. The diagnostic accuracy of the four classifications (S0S1/S2/S3/S4) of the hepatic fibrosis stage was 77.21%. The diagnostic accuracy for significant fibrosis (≥S2), advanced fibrosis (≥S3), and cirrhosis (S4) was 87.50%, 90.93%, and 93.38%, respectively. The AUC values were 0.948, 0.959, and 0.962, respectively.

Conclusion:

RFA can significantly improve the diagnostic performance of HBV liver fibrosis staging. RFA based on serological indices has a good ability to predict liver fibrosis staging. RFA can help clinicians accurately judge liver fibrosis staging and reduce unnecessary biopsies.
Chinese expert consensus on intestinal microecology and management of digestive tract complications related to tumor treatment (version 2022)
Authors: Wang Jun , Liang Jing , He Mingxin , Xie Qi , Wu Qingming , Shen Guanxin , Zhu Baoli , Yu Jun , Yu Li , Tan Xiaohua , Wei Lanlan , Ren Jun , Lv Youyong , Deng Lijuan , Yin Qian , Zhou Hao , Wu Wei , Zhang Min , Yang Wenyan , Qiao Mingqiang , Shu Rong , Xia Zhongjun , Li Zhiming , Huang Ziming , Hu Weiguo , Wang Liang , Liu Zhi , Pi Guoliang , Ren Hua , Ji Yong , Liu Zhe , Qi Xiaofei , Chen Peng , Shao Liang , Chen Feng , Xu Xiaojun , Chen Weiqing , Wang Qiang , Guo Zhi
Published: January 2023

The human gut microbiota represents a complex ecosystem that is composed of bacteria, fungi, viruses, and archaea. It affects many physiological functions including metabolism, inflammation, and the immune response. The gut microbiota also plays a role in preventing infection. Chemotherapy disrupts an organism's microbiome, increasing the risk of microbial invasive infection; therefore, restoring the gut microbiota composition is one potential strategy to reduce this risk. The gut microbiome can develop colonization resistance, in which pathogenic bacteria and other competing microorganisms are destroyed through attacks on bacterial cell walls by bacteriocins, antimicrobial peptides, and other proteins produced by symbiotic bacteria. There is also a direct way. For example, Escherichia coli colonized in the human body competes with pathogenic Escherichia coli 0157 for proline, which shows that symbiotic bacteria compete with pathogens for resources and niches, thus improving the host's ability to resist pathogenic bacteria. Increased attention has been given to the impact of microecological changes in the digestive tract on tumor treatment. After 2019, the global pandemic of novel coronavirus disease 2019 (COVID-19), the development of novel tumor-targeting drugs, immune checkpoint inhibitors, and the increased prevalence of antimicrobial resistance have posed serious challenges and threats to public health. Currently, it is becoming increasingly important to manage the adverse effects and complications after chemotherapy. Gastrointestinal reactions are a common clinical presentation in patients with solid and hematologic tumors after chemotherapy, which increases the treatment risks of patients and affects treatment efficacy and prognosis. Gastrointestinal symptoms after chemotherapy range from nausea, vomiting, and anorexia to severe oral and intestinal mucositis, abdominal pain, diarrhea, and constipation, which are often closely associated with the dose and toxicity of chemotherapeutic drugs. It is particularly important to profile the gastrointestinal microecological flora and monitor the impact of antibiotics in older patients, low immune function, neutropenia, and bone marrow suppression, especially in complex clinical situations involving special pathogenic microbial infections (such as clostridioides difficile, multidrug-resistant Escherichia coli, carbapenem-resistant bacteria, and norovirus).
Progress and prospects for use of cellular immunotherapy in pancreatic cancer
Authors: Tian Jing , Bai Tiankai , Zhang Zhiyong , Zhai Xuan , Wang Kangmin , Gao Xingyi , Yan Bin
Published: January 2023

Pancreatic cancer (PC) is a highly malignant tumor with an increasing incidence rate in recent years. Because pancreatic cancer has an insidious onset, unknown pathophysiology, and poor prognosis, the overall survival rate of pancreatic cancer patients has not improved considerably even with extensive treatment methods such as surgery, radiation, biotherapy, and targeted therapy. Therefore, finding and developing more effective and safe treatments for pancreatic cancer is critical. Cellular immunotherapy has achieved considerable advances in the field of oncology in recent years. Technology is continuously advancing, with new breakthroughs virtually every month, and pancreatic cancer eradication is expected to improve considerably. This article examines the advance of chimeric antigen receptor NK cell immunotherapy (CAR-NK) cell immunotherapy for pancreatic cancer research, as well as research ideas for pancreatic cancer treatment.
Perceived fear and anxiety as an after effect among coronavirus disease-2019 patients and their treating doctors
Authors: Srivastava Rani , Kumar Ashok , Saran Brijesh , Bhagat Tripta , Bansal Shivani , Tyagi Anita , Srivastava Yashaswini
Published: January 2023

Introduction:

Coronavirus disease-2019 (COVID-19) represented a human tragedy among the general population and has been an unprecedented challenge for patients, treating doctors, and the entire world. This fact has created continuous fear, anxiety, and many more psychological discomforts such as impairment in healthy happy life, drug abuse, increased religiosity, and hopelessness, and it is also being noticed that women and women-treating doctors are found to be more prone to catch psychological disturbances.

Objective:

Considering all the above challenges, this study was intended to test the general health, level of fear, anxiety, and general well-being of COVID afflicted individuals and their treating doctors.

Methodology:

Here, the general well-being, level of anxiety, stress, and fear of COVID-19 patients and their treating doctors are examined. This study has been counducted online for COVID-19 patients (with Telephonic calls) and direct interview of treating doctors. The patient's details were taken from hospital records to contact them online. On the other side, the faculty of their treating doctors who have been physically involved in this project were examined for psychological testing. This study has been conducted in the Department of Clinical Psychology in collaboration with Medicine, Santosh Medical College, Hospitals, Ghaziabad, UP.

Results and Discussion:

Out of 1325 total cases, only 34% of cases took interest to provide us feedback after recovery. Approximately the similar proportion of cases, i.e., 35% did not respond but rather gave silly rationales as if they did not want to be recognized. One of the smartest groups of such population was who were proved to be highly fake as they furnished all fake identities even during their admission. It was very shocking. COVID patients did not reveal any serious psychopathology. Now if we compare the psychological profile of treating doctors (faculty and PG), their overall health has shown remarkable concerns means their mental health is affected.

Conclusion:

Therefore, this study concludes that the knowledge and perception about this pandemic and factors associated with anxiety/depression among frontline physicians are needed to be taken care of because it is marked among the doctors of Santosh Hospital.
A Biblical Response to Jehovah Witness in Surabaya, Indonesia
Authors: Juanda  , Eveline Sjanette , Chia Philip Suciadi
Published: January 2023

Issues around Christology are never ending. Both from within and outside Christianity the existence of Jesus as God continues to be discussed. From within the ranks of Christians who systematically deny the Divinity of Jesus are Jehovah's Witnesses. Their spirit of visiting from house to house is commendable and it doesn't matter if Christians are visiting, but what makes noise is visiting non-Christian homes. This is a separate issue in a Muslim majority Indonesia as a Christianization project. On the other hand, visiting Christian households has also created problems in the ecclesiastical sphere. Many have left the church and became members of Jehovah's Witnesses. That is why it is necessary to investigate the cause of such a move. This study uses a qualitative method and a literature study related to Christology and field studies were conducted through interviews with three groups of informants. The result is that the understanding that Christians have, is only built from the belief that 'just believe that Jesus is God'. Even if there is an argument, it is also too weak to be accounted for logically and even easy to break, because the Jehovah's Witnesses even use the original language (Greek) approach, even though only for certain verses that are important to talk about or argue about. Mainstream Indonesian Christians met the group of Jehovah's Witnesses in diverse ways, namely: being randomly visited when they came from house to house, being introduced by friends to help answer important questions, being invited to attend an event held by Jehovah's Witnesses, then also through the printed media which had an interesting design and because of their own curiosity, and then they were ultimately bound.
Early and Progressive Mobility: A Program Implementation Strategy for High Acuity Patient Care Locations
Authors:   , Poland Stefani
Published: January 2023

Despite an increase in the promotion of early progressive mobility, its decrease in hospital-acquired complications and improvement of patient outcomes, there remains a reluctance in staff commitment to daily evaluation and implementation. This is largely due to the fact nurses or other interprofessional staff are the primary individuals responsible for this change in process. A lack of confidence in staff to correctly identify patients that meet criteria and anxiety regarding the safe transfer or mobilization of patients, particularly in high acuity settings have been identified as major barriers. The PICOT question that guided this program development of a CBO toolkit is: For interprofessional staff in high acuity settings such as an intensive care unit (P), how does established competency-based orientation for early and progressive mobility strategies (I) compared to no structured early and progressive mobility program (C) influence the efficacy of recognition and response prioritization for early and progressive mobility (O)? The evidence recommends that increased attention to staff education, specifically identifying criteria and the use of mobility aids increases commitment to EPM. Using the CDC Program Evaluation framework, the Agency for Healthcare Research and Quality (AHRQ) Nurse-driven early mobility protocol, New York State Partnership for Patients (NYSPFP) progressive mobility program toolkit, and Johns Hopkins Activity and Mobility Promotion (JH-AMP) were analyzed to ensure that these programs met requirements for probable success. Strong emphasis on interprofessional staff education and preparedness is imperative for EPM to be maintained. A toolkit that meets knowledge gaps and validates competency will assist with successful commitment to EPM in high acuity patient care areas.
Evidence-Based Best Practice for Nursing Skills Competency Assessment: A Policy Development Project for Standard Work Utilizing the Donna Wright Competency Model
Authors:   , Gentry Iselda
Published: January 2023

Practice Problem: Traditional nursing competency assessments use a process-focused approach determined by leaders. A checklist methodology for conducting nursing competencies does not empower nurses to create their own learning experiences. PICOT: The PICOT question that guided this project was: In an acute care setting (P), how does the development of an evidence-informed policy for competency assessment utilizing the Donna Wright Competency model (I) compared to current competency assessment practices (C), improve the guidance for nurse educators in the development of standard work and communications regarding competency assessment (O)? Evidence: Studies using the DW Competency Assessment Model have shown that this model provides structure and consistency through the collaboration of nursing staff members, nursing leaders, and other key stakeholders. Intervention: The development of an evidence-informed policy for competency assessment using the Donna Wright Competency model was the selected intervention completed over six weeks. Outcome: The development of the policy for competency assessment guided the nurse educators and other key stakeholders with the standard work and communication of competency assessments. Conclusion: A standardized competency practice model, such as the Donna Wright Competency Assessment Model, assists nurses in acquiring higher-quality technical, decision-making, and problem-solving skills. The development of a policy addressing this competency model aims to improve nurses’ knowledge of standardized practices as it relates to nursing competence.
Analysis of heterogeneous and distributed manufacturing environment using Gray Relational Analysis (GRA) Method
Authors: P Nishanth , R Swethana
Published: January 2023

Manufacturing Environment Production of one or more products Dedicated production lines to do or areas. Convenience stores stock items that can manufacture or have them made to order, only if requested by the buyer. The objective of this thesis Finding the best cleaning location Manufacturing Environment or Gray Relational Analysis (GRA) method showing. GRA (Gray Relational Analysis) Method, Cincinnati Milagron T3-726, Cybotech V15 Electric Robot, Hitachi America Process Robot, Unimation PUMA 500/600, United States Robots Maker 110 Alternatives or Load Capacity, Computational Steps for Solving Repeatable Multi-Attribute Decision-Making Problems Node Speed, Memory Capacity, the evaluation parameters reached by the handler The United States Robots Maker 110is got the first rank whereas the Hitachi America Process Robot is having the lowest rank. In this paper Manufacturing Environment United States Robots Maker 110is got the first rank whereas the Hitachi America Process Robot is having the lowest rank
The Impact of Financial Development on the Cost of Capital: Evidence from Pakistan
Authors:   Baluchistan University of Information Technology, Engineering and Management Sciences, Quetta, Pakistan, Javaid Aisha
Published: January 2023

This study adds to the body of knowledge by empirically examining how financial development affects the level of cost of capital of the firms listed on the Pakistan Stock Exchange. This paper applies pooled regression model to the panel data of 150 non-financial firms listed on the Pakistan stock exchange from 2005 to 2017. The aggregate index of financial development and the two sub-indices namely financial market development and financial institutional development are used as measures of financial development; however, the weighted average cost of capital (WACC) is used as a measure of the cost of capital. We found that the cost of capital is likewise inversely correlated with financial development. Our study confirmed that financial market and institutional development are also very negatively correlated with the weighted average cost of capital. These results imply that the level of financial development in the country lowers the average cost of financing as financial development improves governance mechanism, reduces information asymmetry, and risk diversification, mitigates economic uncertainty, and promotes liquidity provisions through stock market development. The empirical evidence of this research is potentially helpful to corporate managers, financial analysts, investors, and policymakers
EDITORIAL: FILLING THE GAPS FOR BIODIVERSITY OF PULAU TINGGI, MERSING, JOHOR TOWARDS SUSTAINABLE CONSERVATION AND MANAGEMENT OF JOHOR MARINE PARKS
Authors:   Universiti Tun Hussein Onn Malaysia, ABDUL-LATIFF MUHAMMAD ABU BAKAR
Published: January 2023

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A NOTE ON THE NEW RECORD OF THE REPTILE FAUNA IN PULAU TINGGI, JOHOR, MALAYSIA
Authors:   Universiti Tun Hussein Onn Malaysia, YIN HUI NG , NGADI EHWAN ,   Universiti Sains Islam Malaysia, ZAINAL MD-ZAIRI ,   Shaz Resort Pulau Tinggi Sdn. Bhd., ABDUL-LATIFF MUHAMMAD ABU BAKAR ,   Universiti Tun Hussein Onn Malaysia
Published: January 2023

Island ecosystem is a fragile ecosystem affected by an ocean climate, which resulting different microclimates, floristic composition and unique habitats. The island’s insularity resulted in the unique composition of animal species, especially reptiles which depend most on the microclimate. Hence, a study on reptile diversity was carried out in Pulau Tinggi, Mersing, Johor from February to October 2019. A previous survey of reptile diversity in Pulau Tinggi was conducted in 2003 and 2006, which recorded 13 and 17 species, respectively and there is an urgent need to update these data. This study used the Visual Encounter Survey (VES) and drift-fenced pitfall traps as the primary sampling methods. 21 species were recorded, which comprise eight families. The Scincidae family recorded the highest number of species, which is five. Meanwhile, Viperidae and Varanidae reported the lowest number of species recorded, one species, respectively. 13 species were reported as new records for Pulau Tinggi, resulting in updated reptile diversity in Pulau Tinggi currently to 32 species based on a comparative literature review with previous studies. These new records indicate that extensive and intensive studies are needed to determine the reptilian diversity in Pulau Tinggi for conservation and management purposes.
BUTTERFLIES AND MOTHS (ORDER: LEPIDOPTERA) IN PULAU TINGGI, JOHOR, MALAYSIA
Authors:   Universiti Tun Hussein Onn Malaysia, YIN HUI NG , AWG ABDUL RAHMAN AQILAH ,   Universiti Tun Hussein Onn Malaysia, ZAINAL MD-ZAIRI ,   Shaz Resort Pulau Tinggi Sdn. Bhd., ABDUL-LATIFF MUHAMMAD ABU BAKAR ,   Universiti Tun Hussein Onn Malaysia
Published: January 2023

Pulau Tinggi is a relatively unexploited island located in the middle arc of the Seribuat Archipelago in Johor, Malaysia. This study is the first to record species of moths and butterflies (Order: Lepidoptera) on the island. Specimens were collected between April and August 2019 through passive sampling methods such as light and baited traps. Active sampling was also done opportunistically using aerial nets. The results showed that Lepidopteran on the island has a high species richness and abundance. A total of 624 individuals from 121 species of Lepidoptera were identified. Out of that, 105 species were butterflies and 16 were moths. The Shannon-Weiner Index (H’) value for both butterfly and moth was 4.29. Evenness, measured using Shannon Equitability Index (EH) was valued at 0.89. Gauging the diversity of fauna in a relatively unexplored island such as Pulau Tinggi is important for properly managing its natural resources. In the near future, activities such as entomotourism may be done in the area to support the local economic ecosystem while ensuring the conservation of the island’s biodiversity.
Anne Sütünün Gastrointestinal Sistem ve Mikrobiyal Çeşitliliğe Etkisi
Authors: MUSLU ATA Tuğçe , KIRAY Esin , KARİPTAŞ Ergin
Published: January 2023

Anne sütü, tam beslenme sağlama yeteneği ve birçok biyoaktif sağlık faktörü nedeniyle yeni doğan bebekler için optimum beslenme rejimi olarak kabul edilmektedir. Anne sütü ile beslenme, mama ile beslenen bebeklere göre daha iyi bir bebek sağlığı ve bağışıklık gelişimi, daha az gastrointestinal hastalık insidansı ve daha düşük ölüm oranları ile ilişkilendirilmektedir. Anne sütü, büyümekte olan bebek için temel besin içeriği sağlamanın yanı sıra, yapısındaki oligosakkaritler ile patojenik bakteriyel yapışmayı önlemekte ve yararlı mikroorganizmaların bağırsakta kolonileşmesini teşvik etmektedir. Başlangıçta anne sütü steril bir sıvı ve izole edilen mikroorganizmalar kontaminant olarak kabul edilirken, günümüzde anne sütünün artık benzersiz bir mikrobiyoma sahip olduğu kabul edilmektedir. Yapılan çalışmalarda insan sütünden türetilen bu suşların, potansiyel probiyotikler olduğu kabul edilebilmektedir. Probiyotik bakteriler patojen bakterilerin aktivitesini engelleyerek kolon başta olmak üzere dolaylı olarak insan sağlığını olumlu yönde etkileyen mikroorganizmalardır. Bu derleme, probiyotik gelişime odaklanarak anne sütü mikrobiyotasının mikrobiyal bileşimini ve anne sütü ve formül mama ile beslenen bebeklerdeki mikrobiyal çeşitliğin kıyaslanması amaçlamaktadır. Ayrıca elde edilen mikrobiyal farklılıkların pek çok hastalıkla ilişkisini ortaya koymayı hedeflemektedir.
Çocuk Gelişimi Lisans Öğrencilerinin Çocukların Karşılaştığı Çevrimiçi Risklere Yönelik Algılarının İncelenmesi: Ankara Üniversitesi Örneği
Authors: TAŞTEPE Taşkın , ÖZÇELİK Dilara , AVCI ÇOBAN Özge
Published: January 2023

Amaç: Bu araştırmanın amacı, çocuk gelişimi lisans öğrencilerinin çocukların karşılaştığı çevrimiçi risklere yönelik algılarının incelenmesidir. Gereç ve Yöntem: Araştırmaya, Ankara Üniversitesi Sağlık Bilimleri Fakültesi Çocuk Gelişimi Bölümünde öğrenim gören 255 öğrenci dâhil edilmiştir. Araştırmada 1. sınıf (n=40) ve 3. sınıf (n=75) olmak üzere toplam 115 öğrenciden elde edilen veriler doğrulayıcı faktör analizi için; 2. sınıf (n=67) ve 4. sınıf (n=73) olmak üzere toplam 140 öğrenciden elde edilen veriler asıl çalışma için değerlendirilmiştir. Araştırmada veri toplama aracı olarak, “Çocukların Karşılaştığı Çevrimiçi Risklere Yönelik Algı Ölçeği” kullanılmıştır. Veriler; betimsel istatistikler, ‘Mann-Whitney U Testi’ ve ‘Kruskall-Wallis H Testi’ ile değerlendirilmiştir. Bulgular ve Sonuç: Yapılan analizler sonucunda, çocuk gelişimi lisans öğrencilerinin sınıf düzeylerine göre çocukların karşılaştığı çevrimiçi risklere yönelik algıları anlamlı olarak farklılaşmaktadır. 4. sınıf öğrencilerinin çocukların karşılaştığı çevrimiçi risklere yönelik algıları, 2. sınıf öğrencilerinin algılarından daha yüksektir. Katılımcıların çocukların karşılaştığı çevrimiçi risklere yönelik algıları çevrimiçi risk deneyimlerine göre farklılık göstermemektedir.
Corona Virüslü Hastalara Bakım Veren Hemşirelerde Depresyon, Anksiyete ve Stres Düzeyinin Belirlenmesi
Authors: PAMUK CEBECİ Sevil , KARA Hilal
Published: January 2023

Amaç: Corona virüslü hastalara bakım veren hemşirelerde depresyon, anksiyete ve stres düzeyinin belirlenmesiçalışmanın amacıdır. Örneklem ve Yöntem: Eylül 2020 tarihinde gerçekleştirilen tanımlayıcı niteliktekiaraştırmanın evrenini, Bilecik Devlet Hastanesi’nde corona virüslü (Covid-19) hastalara bakım veren hemşireleroluşturdu. Örneklemi ise, veri toplama sürecinde ulaşılabilen, araştırmaya katılmayı gönüllü olarak kabul eden, 18yaş üstü, karar verme yetisine sahip, herhangi bir psikolojik hastalığı olmayan, herhangi bir psikolojik ilaçkullanmayan, corona virüslü hastalara bakım veren 70 hemşire oluşturdu. Araştırmada Tanılama Formu veDepresyon, Anksiyete, Stres Ölçeği (DASS 21) kullanıldı. Veriler tanımlayıcı testler ve karşılaştırmalı istatistikyöntemler kullanılarak değerlendirildi. Önemlilik düzeyi p<0.05 kabul edildi. Bulgular: Araştırmaya katılanhemşirelerin yaş ortalaması 30.9±7.6 (20-46) yıl idi. Katılımcıların %80’ini (n=56) kadın, %52.9’u (n=37) evli,%60’ı(n=42) üniversite mezunu, %40’ı (n=28) 10 yıl ve üzerinde mesleki deneyime sahipti. Hemşirelere uygulananDASS-21 ölçeğinden alınan toplam puan ortalamaları; depresyon alt boyutunda 11.39±4.46,anksiyetealt boyutunda14.13±3.74 ve stres alt boyutunda 14.01±3.70 olarak belirlenmiştir. Buna göre katılımcıların %37.1’inin (n=26) çokileri düzeyde depresyonve %85.7’sinin (n=60) çok ileri düzeydeanksiyete,%41.4’ünün (n=29) ileri düzeyde stresbelirtisi yaşadığı saptanmıştır. Sonuç: Corona virüslü hastalara bakım veren hemşirelerde depresyon, anksiyete vestres belirtilerinin yüksek düzeylerde olduğu bulgulanmıştır. Bu faktörler verilen bakım hizmetinin kalitesini deetkileyebilir. Sağlık Bakanlığı Covid-19 psikososyal destek hizmeti, korona virüs pandemisinde online ruhsal destekprogramı (KORDEP) gibi güçlendirme programlarının sağlık çalışanlarına tanıtımının arttırılması ve önerilmesifaydalı olacaktır.
ANALISIS FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN KEIKUTSERTAAN KELAS IBU HAMIL PADA MASA PANDEMI COVID-19
Authors: Mamlukah Mamlukah , Harmilah Ilah Siti , Febriani Esty
Published: January 2023

Angka Kematian Ibu (AKI) merupakan salah satu indikator untuk mengukur derajat kesehatan. Salah satu penyebab tidak langsung diantaranya adalah ibu hamil tersebut tidak mengikuti kegiatan kelas ibu hamil. Kelas ibu hamil di Indonesia sudah terbentuk 89,9% kelas ibu hamil dari 9.993 Puskesmas dan rata-rata tingkat partisipasi kelas ibu hamil masih di bawah 75%. Tingkat partisipasi kelas ibu hamil di Puskesmas Sumedang Selatan masih rendah baru mencapai 50%. Tujuan penelitian untuk mengetahui faktor predisposisi dan faktor penguat yang berhubungan dengan keikutsertaan kelas ibu hamil di wilayah kerja Puskesmas Sumedang Selatan pada masa pandemi Covid-19. Rancangan penelitian cross sectional dengan jumlah sampel 90 responden. Analisis dilakukan dengan unvaried, bivariate dan multivariate. Pengumpulan data dengan wawancara menggunakan kuesioner. Analisis bivariate dari 4 variabel yang diteliti didapatkan hasil hubungan pekerjaan dengan keikutsertaan kelas ibu hamil nilai p:0,011, pengetahuan dengan nilai p: 0,019, sikap dengan nilai p : 0,007 dan dukungan suami dengan nilai p : 0,026. Terdapat hubungan antara variabel pekerjaan, pengetahuan, sikap dan dukungan suami dengan keikutsertaan kelas ibu hamil di wilayah kerja Puskesmas Sumedang Selatan pada masa pandemi covid-19. Perlu adanya evaluasi secara berkala dalam pelaksanaan kelas ibu hamil di puskesmas, untuk perbaikan dan tindak lanjut ke depan.
PERENCANAAN STRATEGIS SISTEM INFORMASI PADA SD NEGERI SAMIRONO MENGGUNAKAN METODE WARD AND PEPPARD
Authors: Karismanto Yogi Danar , Tanaem Penidas Fiodinggo
Published: January 2023

SD Negeri Samirono adalah lembaga pendidikan formal di Republik Indonesia yang bekerja di bawah pengawasan langsung Kementerian Pendidikan dan Kebudayaan. Di era ini organisasi dan perusahaan harus beradaptasi dengan perkembangan teknologi baru untuk tumbuh dan tetap kompetitif. SD Negeri Samirono telah menggunakan teknologi dalam operasionalnya, namun belum sepenuhnya terintegrasi. Perencanaan strategis sangat penting untuk sistem informasi agar lebih berhasil dalam penerapannya dan berkontribusi pada pencapaian tujuan dan visi/misi mereka. Pendekatan Ward dan Peppard telah digunakan selama beberapa dekade sebagai strategi perencanaan strategis untuk sistem informasi. Metode ini mencakup analisis atau kajian lingkungan teknologi informasi internal dan eksternal, serta lingkungan bisnis internal dan eksternal, yaitu dengan menggunakan analisis SWOT dan analisis Value Chain. Output yang dihasilkan dari pendekatan perencanaan strategis ini menghasilkan pembuatan portofolio aplikasi, yang selanjutnya dipetakan menggunakan McFarlan Strategic Grid. Temuan akhir studi ini mencakup rekomendasi untuk pembuatan dan perbaikan aplikasi atau sistem untuk dikembangkan dan diimplementasikan. Antara lain sistem informasi PPDB, sistem informasi akademik, sistem informasi sarana prasarana, website company profile sekolah, e-absensi dan e-learning. Tujuan dari penelitian ini adalah supaya output yang direkomendasikan dapat dijadikan acuan untuk  pengembangan dan implementasi sistem informasi pada SD Negeri Samirono. Sehingga melalui acuan tersebut dapat membantu SD Negeri Samirono lebih unggul, kompetitif dan lebih berprestasi.
ANALISIS KEMAMPUAN GURU PENGGERAK PADA JENJANG SEKOLAH DASAR DI WILAYAH PERBATASAN DALAM PERSPEKTIF LITERASI TEKNOLOGI DIGITAL
Authors: Silvester Silvester , Purnasari Pebria Dheni , Aurelly Betrishandi Titia , Gunawan Rendi
Published: January 2023

Penelitian ini bertujuan untuk menganalisis kemampuan guru penggerak pada jenjang sekolah dasar di wilayah perbatasan dalam perspektif literasi teknologi digital. Penelitian ini merupakan jenis penelitian kualitatif dengan pendekatan kualitatif deskriptif. Sumber data dalam penelitian diperoleh melalui observasi, studi pustaka, dan wawancara yang dilakukan bersama responden. Adapun subjek dalam penelitian ini adalah 5 orang guru penggerak yang berada di wilayah Kabupaten Bengkayang. Teknik pemilihan responden dilakukan dengan menggunakan purposive sampling. Pemilihan subjek tersebut   dilatarbelakangi karena tujuan dari penelitian ini yaitu untuk menganalisis kemampuan guru penggerak di Wilayah Perbatasan dalam Perspektif Literasi Teknologi Digital. Teknik analisis data dalam penelitian ini menggunakan analisis data yang dikembangkan oleh Miles dan Huberman yaitu dimulai dengan reduksi data, penyajian data dan penarikan kesimpulan dari data yang sudah dikumpulkan. Untuk menguji keabsahan data dalam penelitian ini digunakan teknik triangulasi. Hasil penelitian yang dilakukan di wilayah perbatasan yakni di Kabupaten Bengkayang menunjukkan bahwa sebagian guru penggerak sudah menguasai literasi teknologi digital, hal ini dapat dilihat dari pemahaman para guru penggerak tentang teknologi digital. Para guru berpendapat bahwa teknologi digital merupakan sebuah perkembangan teknologi yang berinovasi sebagai media atau alat yang dapat membantu penggunanya dalam memberikan dan mendapatkan informasi secara praktis. Para guru juga sudah menggunakan berbagai fasilitas teknologi dan memanfaatkan teknologi digital ini sebagai media pembelajaran dalam proses pembelajaran sebagai pemberian materi dan evaluasi pembelajaran serta dapat dimanfaatkan sebagai sumber belajar bagi para peserta didik dan para guru. Namun belum sepenuhnya para guru memanfaatkan teknologi digital sebagai media pembelajaran maupun evaluasi pembelajaran. Hal ini karena kondisi wilayah perbatasan masih tertinggal dan belum merata dalam aspek infrastruktur pendukung pendidikan.
MOVIE-INDUCED TOURISM SEBAGAI GAGASAN PEMAJUAN PEMBERDAYAAN MASYARAKAT PESISIR INDONESIA DALAM PERWUJUDAN POROS MARITIM DUNIA
Authors: Wiswayana Wishnu Mahendra
Published: January 2023

Poros Maritim Dunia sejak dicanangkan oleh Presiden Joko Widodo pada KTT Asia Timur 2015 di Myanmar menjadi nafas setiap kebijakan strategis di Indonesia. Salah satu pilar yang memiliki posisi penting adalah membangun kembali budaya maritim di Indonesia. Strategis dalam hal ini karena menyangkut kesadaran diri bangsa Indonesia atas karakternya sendiri. Secara khusus, dalam hal ini masyarakat pesisir memiliki kontak langsung dengan budaya maritim setiap hari. Melalui film, sebagai salah satu budaya populer; budaya maritim di Indonesia dapat lebih diidentifikasi dan dilakukan dengan pendekatan yang sarat dengan unsur hiburan. Penelitian ini bersifat kualitatif dengan sumber data dan literatur yang berkaitan dengan Poros Maritim Dunia dan pariwisata yang diinduksi film. Temuan menunjukkan bahwa ada contoh yang dapat di replikasi menjadi ide pemberdayaan masyarakat pesisir di daerah ataupun kawasan lain.
PEMAHAMAN MATEMATIS BERDASARKAN MODEL PEMBELAJARAN DAN SELF CONCEPT
Authors: Busnawir Busnawir , Herlin Herlin
Published: January 2023

Tujuan penelitian ini ialah untuk menganalisis perbedaan pemahaman matematis yang dihasilkan oleh model pembelajaran berbasis masalah dan konvensional berdasarkan self concept tingi dan rendah. Penelitian ini menggunakan desain eksperimen semu dalam bentuk posttest-only control design. Populasi penelitian ialah seluruh peserta didik kelas VIII SMP Negeri 5 Kendari tahun pelajaran 2021/2022 sebanyak 8 kelas paralel. Sampel penelitian dipilih 2 kelas menggunakan teknik random, kemudian diperoleh kelas VIII-3 sebagai kelas eksperimen dan kelas VIII-7 sebagai kelas kontrol. Data penelitian dianalisis menggunakan two way Anova dan independent sample t-test. Hasil analisis deskriptif menunjukkan kemampuan pemahaman matematis peserta didik berada dalam kategori sedang, baik yang diajar dengan model pembelajaran berbasis masalah maupun model pembelajaran konvensional; namun secara kuantitatif model pembelajaran berbasis masalah menghasilkan pemahaman matematis lebih tinggi dibandingkan model pembelajaran konvensional. Pada peserta didik dengan self concept kategori tinggi memiliki pemahaman matematis yang lebih tinggi dibandingkan peserta didik dengan self konsep kategori rendah baik diajar dengan model pembelajaran berbasis masalah maupun diajar dengan model pembelajaran konvensional. Disimpulkan bahwa model pembelajaran berbasis masalah menghasilkan pemahaman matematis lebih baik dibandingkan pembelajaran konvensional baik pada self concept kategori tinggi maupun pada self concept kategori rendah.
KAPASITAS NILAI KUAT TEKAN BETON DENGAN HAMMER TEST DAN ULTRASONIC PULSE VELOCITY (UPV) JEMBATAN LOA HAUR
Authors: Tumingan Tumingan , Alwi Salma , H Fendi Ilham
Published: January 2023

Jembatan  Loa Haur merupakan sebuah jembatan tipe rangka baja dengan bentang 60 meter dibangun pada tahun 1992 yang terletak pada Jalan Poros Samarinda – Tenggarong, Desa Bakungan, Kecamatan Loa Janan Kutai Kartanegara Kalimantan Timur. Akibat kondisi lalu lintas dan beban kendaraan yang melintas semakin meningkat di jembatan Loa Haur, untuk keamanan dan kenyamanan pengguna, di perlukan evaluasi struktur jembatannya. Salah satu bagian struktur yang akan dievaluasi pada penelitian ini yakni mutu beton yang terpasang saat ini terhadap standar spesifikasi Bina Marga khususnya sisa kekuatan tekan beton jembatan dengan batas minimal mutu beton 250 Kg/cm2, atau 20 MPa. Pengujian ini mengambil metode non destructive menggunakan alat Hammer test dan alat Ultrasonic Pulse Velocity Test. Pengujian diawali dengan alat rebar locator yang bertujuan untuk mendeteksi diameter dan posisi tulangan dalam elemen beton, serta ketebalan selimut beton dengan memanfaatkan medan elektromagnetik, yang mudah terpengaruh oleh adanya logam/metal berupa tulangan baja di dalam beton, karena alat Ultrasonic Pulse Velocity Test sangat terganggu bila melewati baja tulangan. Dilanjutkan dengan pengujian menggunakan alat Hammer test dengan mengambil sebanyak 120 titik pada abutmentt dan  63 titik pada Pelat lantai. Untuk alat UPV dengan metode Tidak Langsung mengambil sampel sebanyak 49 titik pada abutmentt dan 20 titik pada plat lantai jembatan. Hasil analisis pengujian diperoleh nilai kekuatan tekan beton menggunakan alat Hammer test pada abutment dan pelat lantai jembatan masih memenuhi standar spesifikasi jembatan yaitu sebesar 479 kg/cm2 dan 454 kg/cm2 , sedangkan nilai kekuatan tekan beton hasil uji UPV pada abutment dan pelat lantai juga masih memenuhi standar spesifikasi jembatan  yaitu sebesar 265 kg/cm2 dan 243 kg/cm2.
IMAJINASI PEREMPUAN DALAM MEDIA POSTER SINGAPORE GIRL DALAM IKLAN SINGAPORE AIRLINES
Authors: Budiardjo Hardman , Sulistiowati Sulistiowati , Sutikno Sutikno , Setyawan Henry Bambang , Tjandrarini A. B.
Published: January 2023

Penelitian ini dilakukan untuk mengidentifikasi imajinasi tentang perempuan dalam media poster Singapore Girl yang dilakukan oleh maskapai Singapore Airlines. Penelitian ini dilakukan untuk mengidentifikasi poster tersebut yang berkaitan dengan imajinasi perempuan dalam iklan poster Singapore Girls yang dihubungkan dengan nilai individu dan nilai perusahaan. Penelitian yang berhubungan dengan media above the line dan yang dikaitkan dengan nilai diri belum pernah dilakukan. Penelitian yang ada berhubungan lebih menekankan terhadap nilai individu dan berhubungan dengan nilai perusahaan dan tidak menggunakan media poster. Penelitian yang dilakukan menggunakan metodologi visual dengan site of image it self pada tataran modality social. Site of image it self merupakan pemaknaan dari sudut pandang peneliti. Peneliti dalam hal ini bersifat tunggal tidak berfungsi sebagai audien dalam mengintepretasikan visual image yang dihubungkan dengan konteks. Dengan mendasarkan pada realitas sosial, peneliti harus aktif mengamati gambar, tanda dan mengaitkannya dengan konteks untuk mengidentifikasikan tujuan pesan disampaikan. Penelitian ini menggunakan  teori Semiotika Roland Barthes sebagai pisau bedah atau unit analisis. Tahapan dalam penelitian ini dilakukan dengan mengamati poster iklan secara mendalam, yang dilanjutkan dengan mengamati potongan-potongan gambar yang akan dianalisis berdasarkan referensi-referensi yang ada. Hasil penelitian menunjukkan bahwa poster iklan Singapore Girls pada maskapai Singapore Airlines memiliki konotasi great individual value dan great corporate Value pada tataran pertama. Pada tataran kedua great individual value adalah mitos. Inilah gambaran paradoks tentang great individual value dan great corporate value hasil konstruksi media yang tidak terlepas dari politik ekonomi yang berhubungan dengan kapitalis.
PENINGKATAN HASIL BELAJAR SEJARAH SISWA DENGAN MEMANFAATKAN MEDIA CERITA BERGAMBAR
Authors: Darnawati Darnawati , Jamiludin Jamiludin , Lenisa Lenisa
Published: January 2023

Tujuan penelitian ini yaitu, pertama untuk peningkatan keefektifan pengajaran guru pada pembelajaran sejarah dengan penerapan media cerita bergambar; kedua, untuk peningkatan aktivitas belajar siswa pada pembelajaran sejarah; dan ketiga untuk penggunaan media cerita bergambar dalam peningkatan hasil belajar siswa pada pembelajaran sejarah. Penelitian Tindakan Kelas merupakan metode yang digunakan dalam penelitian ini. Guru aktif yang sedang mengajarkan sejarah dan siswa kelas XI di SMA Negeri 1 Kaledupa merupakan subjek pada penelitian ini. Prosedur penelitian telah dilaksanakan sebanyak 2 siklus. Observasi dan tes digunakan dalam pengumpulan data. Hasil penelitian menunjukkan bahwa: (1) Keefektifan mengajar guru pada mata pelajaran sejarah melalui penerapan media cerita bergambar pada siklus I mencapai 72%. Setelah diadakan perbaikan pada siklus II, efektivitas mengajar guru menjadi meningkat hingga mencapai 100%, (2) Aktivitas belajar siswa pada mata pelajaran sejarah melalui penerapan pembelajaran media cerita bergambar pada siklus I mencapai 71%. Setelah  diadakan perbaikan pada siklus II, aktivitas belajar siswa mengalami peningkatan menjadi 93%. Dengan demikian, telah mencapai indikator kinerja yakni 90%, (3) Hasil belajar siswa pada mata pelajaran sejarah melalui penerapan media cerita bergambar pada siklus I hanya mencapai 78% dan setelah diadakan perbaikan pada siklus II, hasil belajar siswa mengalami peningkatan menjadi 100%. Dengan demikian telah mencapai indikator kinerja yakni 80%.  Berdasarkan hasil penelitian ini, dapat disimpulkan bahwa melalui penerapan media cerita bergambar dapat meningkatkan keefektifan mengajar guru, aktivitas belajar siswa dan hasil belajar siswa.