bluuebunny/crossref_metadata_2025 huggingface dataset:
EFFECT OF DI-(2-ETHYLHEXYL) PHTHALATE (DEHP) EXPOSURE ON MICROARCHITECTURE OF FEMORAL BONE IN MALE LABORATORY MOUSE: PRELIMINARY RESULTS
Authors: Šulková Eva , Babosová Ramona , Kolena Branislav , Poláčiková Zuzana , Hlisníková Henrieta , Šidlovská Miroslava , Vondráková Mária , Martiniaková Monika , Petrovičová Ida
Published: February 2022

Di-2-ethylhexyl phthalate (DEHP) is a toxic and hazardous endocrine disruptor with adverse effects on animal and human health. However, its impact on bone tissue has not been sufficiently investigated. Therefore, the purpose of our preliminary study was to examine the effects of DEHP on compact bone structure in two 57-days-old male mice. Daily oral administration of DEHP (4.5 mg/kg body weight dissolved in 500 µl of peanut oil per 15 days) was studied, compared to a control. We observed a significant effect of DEHP exposure on macroscopic bone characteristics. Similarly, we identified differences in qualitative characteristics, such as the presence of resorption lacunae and absence of non-vascular and primary vascular radial bone tissue near the endosteal border, compared to the control. On the contrary, quantitative analysis showed no demonstrable alterations in morphometric parameters. Our preliminary findings support the hypothesis about the negative impact of DEHP on bone tissue. However, further investigation is needed to understand this issue better and more precisely.
CONTROL OF THERMOPHILIC SPORES BY SPORICIDAL AGENTS AND THERMAL INACTIVATION
Authors: Karakaya Ayse Busra , Karaca Basar , Ozcan Birgul , Coleri Cihan Arzu
Published: February 2022

In this study, the adhesion patterns of thermophilic spores of Geobacillus thermodenitrificans DSM 465T, Geobacillus thermoglucosidans B84a, Anoxybacillus kamchatkensis subp. asaccharedens F81 and Anoxybacillus flavithermus DSM 2641T, all of which are biofilm producers in dairy products, were investigated by epifluorescence microscopy on 6 different abiotic surfaces commonly used in the dairy industry. The spores of G. thermodenitrificans DSM 465T and A. kamchatkensis subp. asaccharedens F81 were found to adhere mainly to rubber, polycarbonate, PTFE and stainless steel surfaces. In addition, the efficacy of sporicidal agents on the spores of these bacteria was investigated and only peracetic acid, cetylpyridinium chloride and formaldehyde were found to be the most effective of the sporicidal agents tested. Among the sporicidal agents that showed high efficacy against spores, peracetic acid and nitric acid were selected because they had the shortest contact time, low toxicity and cost. Binary combination effects were tested by determining the LD50 values of the selected agents and it was found that there was a synergistic effectbetween these two effective chemicals. In addition, the thermal resistance profiles of planktonic and sessile spores of A. flavithermus DSM 2641T and G. thermodenitrificans DSM 465T were evaluated.
ETHANOL PRODUCTION FROM SONICATED SWEET SORGHUM BAGASSE BY CO-CULTURE OF PLEUROTUS OSTREATUS AND TRICHODERMA HARZIANUM
Authors: Madigal James Paul , Calica Dane Mikhael , Agrupis Shirley , Birginias Ma. Concepcion
Published: February 2022

The study aimed to develop a novel bioprocessing protocol for lignocellulose conversion into ethanol without the use of any chemical for pre-treatment. The feedstock, mature sweet sorghum bagasse, was milled and sieved to 40 and 80 mesh (physical treatment) to have samples with particle size of 0.425 mm and 0.180 mm, respectively. After which, samples were inoculated with either single or co-culture of P. ostreatus and T. harzianum (biological) for 28 days followed by sonication (mechanical) with varying time duration. The effectivity of the different treatments under each protocol was evaluated based on delignification and saccharification of the biomass complex via spectrophotometric standard analytical procedure. Cellulose-derived glucose was inoculated with S. cerevisiae under anaerobic conditions to assess its fermentability. Testing of the different treatment combinations was conducted at 5g substrate while the best treatment combination was validated at both 5g and 100g levels. Independent optimization trials of the different treatments showed the significant effect of smaller particle size of 0.180 mm, co-culture of P. ostreatus and T. harzianum, and sonication time of 20 min in improving the delignification and saccharification efficiencies of the sweet sorghum biomass. These parameters were combined together as one protocol (physico-bio-mechanical). Saccharification efficiency of this protocol under the 5g scale is ±10.67% against ±9.96% at 100g-scale. This is a big leap compared to the ±3.0-5.0% obtained in our previous experiment. Ethanol yield obtained from the same condition were 2.73%w/w and 1.77%w/w for the 5g and 100g-scale, respectively. It can be confidently stated here, that the present study is the first to ever produce cellulosic ethanol at laboratory-scale condition without chemical pre-treatment.
THE INFLUENCE OF NON-TRADITIONAL FRUITS AND ELDER FLOWERS ON RHEOLOGICAL PROPERTIES OF THE DOUGH
Authors: Kolesárová Anna , Bojňanská Tatiana , Kopčeková Jana , Kolesárová Adriana
Published: February 2022

The influence of the addition of flowers (Flos sambuci L.) and berries of elderberry (Sambucus nigra L.), blackcurrant (Ribes nigrum L.) and chokeberry (Aronia melanocarpa L.) to wheat flour was characterized by the rheological test Mixolab (Chopin Technologies, France). Twelve types of wheat flour mixture with different fruit and elder flowers addition were prepared for evaluation in the following ratios: 95: 5, 90:10, 85:15. The control represented 100 % wheat flour. Preliminary rheological analyzes indicated a strong influence of the ingredients used on the properties of the dough.  The addition of elderflowers, elderberry and blackcurrants significantly increased the values of the dough development time. In the samples with the addition of elder flowers, we also found a higher stability of the dough, on the contrary, the addition of berries of elderberry and also the 15% addition of chokeberry reduced it. The most significant effect of increasing the addition on the development time and stability of the dough was observed in the samples with the addition of blackcurrant. In contrast to the other samples, the properties of the flour with the addition of elder flowers were comparable with the control flours in protein strength, in starch gelatinization and in the estimated amylase activity. Samples of flour with the addition of lyophilized fruits behaved significantly differently rheologically than flour with the addition of elder flowers. The closest relationship (p <0.001) was observed between the torque C3 (starch gelatinization rate) and C4 (stability of the formed gel), also between C3 and the difference C3-C2 (r = 0.99).
NOVEL SPECIFIC PRIMERS FOR THE SPECIFIC DETECTION OF FUSARIUM OXYSPORUM F. SP. CUBENSE BASED ON SYBR GREEN REAL-TIME PCR
Authors: Prachaiboon Nongnid , Thanyasiriwat Thanwanit , KAWICHA Praphat
Published: February 2022

Fusarium oxysporum f. sp. cubense (Foc) is the causal agent of Fusarium wilt of banana worldwide. Foc is transmitted to another banana plantation via an infected banana sucker. A specific and sensitive detection assay could be used for disease-free propagule screening to prevent disease dispersal effectively. In this study, SYBR green-based real-time PCR assay was developed based on novel specific primers targeting the large subunit of RNA polymerase II (RPB1) gene. The partial RPB1 gene was amplified and sequenced from Foc isolate FOC1708 and SK3-2. Regions specific for Foc were identified and used for designing real-time PCR primers. The specificity of the designed primers was evaluated on genomic DNA from Foc isolates and non-target microorganisms. The results showed that the designed primers were specific to only Foc isolates from race 1 and tropical race 4 (TR4). The detection efficiency of the designed primers was compared to other published primers through optimized SYBR green-based real-time PCR assay and nested PCR. The new primers could detect the Foc genomic DNA at a minimum of 5 pg and target pathogen in a symptomless banana sucker. The specificity and sensitivity of the new primers were comparable to the published real-time PCR primers and the nested PCR assay. This developed assay with these novel primers can aid the disease quarantine for effective prevention and control of the Fusarium wilt of banana.
DEVELOPMENT AND APPLICATION OF ANTIOXIDANT COATING ON Fragaria spp. STORED UNDER ISOTHERMAL CONDITIONS
Authors: Finardi Sarah , Hoffmann Tuany Gabriela , Angioletti Betina Louise , Mueller Eduarda , Lazzaris Raissa Souza , Bertoli Sávio Leandro , Hlebová Miroslava , Khayrullin Mars , Nikolaeva Natalia , Shariati Mohammad Ali , Krebs de Souza Carolina
Published: February 2022

Strawberry (Fragaria spp.) is a non-climacteric fruit, widely consumed in several countries, but is extremely sensitive and susceptible to mechanical damage during harvest, transport, and storage, reducing the shelf life. In order to prolong the shelf life of this product, edible starch-based coatings were developed, with propolis extract (MSP) and without the addition of ethanolic propolis extract (MS) and uncoated samples, used as control (MC). All samples were stored under isothermal conditions (4 °C ± 0.5 °C), for 10 days. Physicochemical analyzes (pH, mass variation, vitamin C, color, and phenolic compounds) were carried out to characterize and identify the coating efficiency in the conservation of strawberries. The formulations of the coatings with and without the addition of propolis had a significant (p ≤ 0.05) effect on the variation of fruit weight. The propolis coating showed greater stability in the vitamin C content and pH levels, up to the 10th day of cold storage, in comparison to the samples with starch coating and the control. The treatments (MS, MSP, and MC) did not significantly influence (p > 0.05) the color and the content of total polyphenols.
IN VITRO EFFECT OF NEWLY BACTERIOPHAGES ISOLATES AGAINST ESCHERICHIA COLI SEROGROUPS COLLECTED FROM THE LOCAL HOSPITAL LABORATORY; THEIR SPECIFIC CHARACTERIZATION AND IDENTIFICATION
Authors: Jamalludeen Nidham , Shakir Dania
Published: February 2022

The aim of this study is to isolate a new bacteriophage with lytic effect against several serogroups of Escherichia coli that were isolated from different samples submitted to the local hospital laboratory. These serogroups are the main causative agents of bloodstream and urinary tract infections (UTIs) among Gram-negative bacteria. Three isolates of E. coli were used as a host to isolate phages from a hospital wastewater treatment plant. Eight phages were isolated and only three of them (EC-BSR1, EC-BSR2, and EC-BSR3) were considered for further characterization and identification. The three phages appear to belong to Myoviridae characterized by icosahedral heads, necks and contractile tails with tail fibers. Phage EC-BSR1 and EC-BSR2 had genome sizes of 67.06 and 68.04 kb, respectively. All three phages were lysed 100% of E. coli serogroups that was tested in vitro and 42.7%, 61.7% and 44.7% in vitro lyses of ECOR collection reference. Phages were resistant to pH from 5 to 9, and phage EC-BSR3 appeared to be more resistant than the other two phages to an acidic and alkaline environment. These phages have the pattern of homologous DNA fragments after being digested with Acc1 and EcoR1 restriction enzymes. It was concluded that these phages are highly coli lytic for the E. coli serogroups isolates.
THE ANTIMUTAGENIC EFFECT OF MULTIFLORAL HONEY IN SALMONELLA/ MICROSOMAL ASSAY AND ITS CORRELATION WITH THE TOTAL POLYPHENOLIC CONTENT
Authors: BOUACHA Mabrouka , BOUDIAR Ines , ABDI Akila , Al-KAFAWEEN Mohammad Abdulraheem , KHALLEF Messaouda
Published: February 2022

The objective of this study is to determine the antimutagenic effect of honey and its correlation with the concentration of the total polyphenolic content. Seven honey samples were collected from different regions of Algeria. The total polyphenolic content was determined by Folin-Ciocalteu colorimetric assay. The antimutagenic effect was carried out by the AMES Salmonella/ microsome mutagenicity assay against three known mutagenic substances (4-nitro-o-phenylenediamine, sodium azide, and mitomycin C), using Salmonella typhimurium TA98, TA100, and TA102 strains.
The results obtained revealed that Algerian honey contains high polyphenol content, which varied significantly between 38.04 and 286.28 µg of GAE/100 mg of honey. This variation is due to their different botanical and regional origins. In addition, all tested honey exhibited an antimutagenic effect against mutagenic substances; honey is effective to inhibit between 29.18±11.11 % and 73.14±11.14 % of mutagenic activity of chemical substances. There is a strong positive correlation between the total polyphenolic content and the antimutagenic proprieties of honey against the mutagenic substances.
The results obtained suggest that honey is effective as an antimutagenic agent; it can play an important role in the protection of the mutagenic effect of DNA caused by chemical substances.
MYCOBIOTA AND CO-OCCRURENCE OF MYCOTOXINS IN GREEN AND ROASTED COFFEE BEANS
Authors: Hlebová Miroslava , Uzsáková Viktória , Podhorská Lenka , Vešelenyiová Dominika , Mrkvová Michaela , Čuboň Juraj , Hleba Lukáš
Published: February 2022

A total of 20 samples of green and roasted coffee beans (the same varieties as green coffee beans were used) [Coffea arabica L. (19 samples) and Coffea robusta L. (1 sample)] were collected from the various coffee roasters in Slovakia (2017/2020) and their mycobiota were analyzed. Mycological analysis was carried using standard media with focus on genera Aspergillus and Penicillium. To determine endogenous and exogenous mycobiota the method of direct placing of surface-sterilized coffee beans (green and roasted) on agar plates and the plate dilution method were used. All obtained pure cultures were classified into the genera and identified to the species according to micro- and macromorphological properties. Next the potentially toxigenic isolates were tested on their ability to produce mycotoxins (cyclopiazonic acid, penitrem A, sterigmatocystin, aflatoxins (AFB1, AFG1), ochratoxin A, patulin, roquefortine C, citrinin, and griseofulvin). From green coffee samples with higher isolation frequency (FR%) and relative density (RD%) were the genus Aspergillus (FR 100% and RD 67.39%) and the genus Penicillium (FR 90% and RD 24.60%) recorded. Aspergillus section Nigri was the most widespread in green coffee samples (RD 47.7%). The genus Aspergillus was the most occurred genus in roasted coffee bean samples, too (RD 36.58%; FR 90%). In green and roasted coffee samples were detected mainly producers of aflatoxins (AFB1 and AFG1), cyclopiazonic acid, OA, sterigmatocystin and patulin. Due to the detected presence of mycotoxins in green as well as in roasted coffee bean samples, it is very important to prevent fungal contamination and control of coffee beans before and after roasting process.
Application of Pancasila as the Ethical System of the Indonesian Nation
Authors: Susilawati N  , Bambang Niko Pasla
Published: February 2022

Ethics is related to good living habits, and good living procedures, for individuals or society. In this sense, ethics is the same as morals. Ethics in a broad sense is the science that discusses the criteria of good and bad. Ethics are generally understood as philosophical thoughts about everything that is considered good or bad in human behavior. Ethics is always related to the issue of values ​​so the discussion about ethics generally talks about issues of good or bad values. Pancasila as an ethical system is very urgent to be applied in the life of a nation and state because of the problems faced by the Indonesian people, among others: 1) The many cases of corruption that hit the State of Indonesia so as to weaken the joints of life as a nation and state, 2) The occurrence of acts of terrorism in the name of religion so that it can damage the spirit of tolerance in inter-religious life, and melt the spirit of unity or threaten the disintegration of the nation, 3) Human rights violations still occur in the life of the state, 4). The gap between rich and poor groups still marks the lives of Indonesian people, 5) legal injustice that still colors the judicial process in Indonesia and 6) Many rich people are not willing to pay taxes properly. The strategy for implementing Pancasila as an ethical system in the life of the nation and state for the Indonesian people is carried out as follows: 1) Character education. 2) Reference Criteria for State Administrators, 3) Raising Awareness of Taxpayers, 4) Manifestation of the Pancasila Value in the Human Rights Law and 5) Manifestation of the Pancasila Value in the Environmental Law.
Implementation of Coaching in the Change Action Agenda for Supervisory Leadership Training (PKP) Participants in 2021 at the Human Resources Development Agency of Jambi Province
Authors: Eti Fitriani
Published: February 2022

In the implementation of Supervisory Leadership Training (PKP), the role of Widyaiswara is not only limited to being a teacher or facilitator but also plays a role as a coach in guiding Action for Change. Action for Change is a working paper for PKP participants whose assessment weight reaches 50 (fifty) percent of the total final score of the participants. In order for participants to get the expected results when participating in the training, the coach is expected to be able to carry out his role to the maximum, starting from the preparation of the change action plan, the implementation process in the workplace, and during the preparation of the change action report. Seeing the importance of this, in this study, the author will try to describe how the coaching process is carried out by coaches and analyze it by comparing it with theories about coaching and regulations issued by LAN regarding morning coaching for PKP participants. Field findings show that the coaching process is in accordance with LAN requirements, the coaches have carried out their role as coaches to explore the potential of participants and provide guidance, motivating participants from the beginning of the mentoring process and when they face obstacles in the field, but when compared with theory-based -The specific skills needed to become a reliable coach, still need development efforts through activities, workshops/training to improve the coaching skills of Widyaiwaras in Jambi Province, which are expected to have an impact on improving the quality of action results changes in PKP participants at BPSDM Jambi Province.
New cultivars: Dionaea 'Scarlatine', Dionaea 'Scarlet Fever, Sarracenia purpurea 'Phoenix', Sarracenia 'Zjahnine'
Authors: Blacher Lucien , Belanger Christoph , Brook Julian
Published: February 2022

The cultivars Sarracenia purpurea 'Phoenix', Dionaea 'Scarlatine' (English: D. 'Scarlet Fever'), and Sarracenia 'Zjahnine' are described.
A case of bird capture by a cultivated specimen of the hybrid Nepenthes x mixta
Authors: Hewitt-Cooper Nigel
Published: February 2022

As a nurseryman, I’m used to being asked what is the biggest prey item caught by my plants. Of course, as a general rule the answer is insects, but there are some species, especially Nepenthes, which can consume larger animals such as lizards, frogs, small rodents, and even rats—as has been well documented. Indeed there have been several reports of cultivated Nepenthes specimens catching mice, although it is hardly common in comparison to wild plants where a much broader spectrum of fauna is to be found.
Fishing spiders in the hanging stomachs of Borneo
Authors: Pollard Simon D.
Published: February 2022

Desperate for a drink, the famous naturalist Alfred Wallace drank the liquid from a group of pitcher plants while exploring Malaysia. Although the fluid was full of dead insects and looked “uninviting”, he wrote in 1890 that he and his friends “found it very palatable, though rather warm, and we all quenched our thirst from these natural jugs”. They must have been almost delirious with dehydration to have quaffed a few pitchers, as one local name for these plants translates to “the place where rats pee”, probably because of the urine-like smell from decomposing insects. While I have drunk the fluid from unopened pitchers of Nepenthes gracilis (slightly sweet and slimy), when it smells like a rat urinal, and comes from a vessel often called a “hanging stomach”, it does not sound like a drink that will improve with age.
Mineral nutrition in hydroponically-grown Pinguicula
Authors: Guitton Yann , Legendre Laurent , Adamec Lubomír
Published: February 2022

Hydroponic cultivation consists of growing plants on inert substrates with liquid mineral nutrient solutions. It has recently become popular for home-growing plants in limited spaces and for large-scale greenhouse production of crop plants. It is also a valuable tool for the scientific investigations of plant mineral nutrition. Despite the importance of mineral nutrition in the carnivorous syndrome, there is no recent report on the potential usefulness of hydroponics as an investigation tool for studying mineral nutrition of carnivorous plants. The goal of this study was to evaluate the growth response of carnivorous plants of the genus Pinguicula on a peat-based and a rockwool-based hydroponic set-ups under various conditions of mineral deficiencies.
Mycorrhizal formation by various carnivorous plants
Authors: Santiago Yana , Darnowski Douglas W.
Published: February 2022

Carnivorous plants receive the greatest amount of attention for their modified leaves used for obtaining extra nutrients while they live in low-nutrient soils. Another way in which plants obtain more nutrients when nutrients in the soil are limiting is the formation of mycorrhizae with fungi. The fungi provide a large, highly-absorptive surface area for the plants, able to scavenge rare nutrients efficiently, while the plants provide their fungal partners with carbohydrates. This mycorrhizal habit is found in many forest trees and also in most heaths and in some epiphytes and orchids. More and more plants are being discovered to be mycorrhizal.
The digestive fluid of Drosera indica contains a cysteine endopeptidase (“droserain“) similar to dionain from Dionaea muscipula
Authors: Takahashi Kenji , Nishii Wataru , Shibata Chiaki
Published: February 2022

Carnivorous plants are known to secrete various endopeptidases extracellularly to digest prey proteins. Previously we purified two isoforms of nepenthesin to homogeneity and elucidated their enzymatic and structural characteristics. In a continuation of these studies, we have been attempting to characterize these and other endopeptidases secreted by carnivorous plants to digest prey proteins. Recently, we found and partially characterized a cysteine endopeptidase in the digestive fluid of Dionaea muscipula and named it “dionain”. In the present report, we describe the occurrence of a similar cysteine endopeptidase in the digestive fluid of Drosera indica and propose the name “droserain” to this enzyme. In this connection, we also propose the names of aspartic endopeptidases from the digestive fluids of relevant carnivorous plants.
New cultivars
Authors: Crow Christopher , Bres Olivier , Amici Andrea , Passkiewicz Fred , Chen Yi , Fisch Alexander , Blacher Lucien
Published: February 2022

The cultivars Sarracenia 'Brimstone', Sarracenia 'Giant Cotton', Sarracenia 'Iamsatyricon', Sarracenia 'Mercury', Sarracenia moorei 'Snow Lee', Cephalotus 'Round Leaf Big Daddy', Dionaea muscipula 'Alternance', and Dionaea muscipula 'Lezard Vert' are described.
Nepenthes robcantleyi: A natural hybrid
Authors: Mansell Geoff , Suarez Wally
Published: February 2022

This paper is a follow-up to the protologue of the newly described Nepenthes nebularum, and presents details leading to the inevitable conclusion that N. robcantleyi is not a species but a natural hybrid originating from a combination of N. truncata Macf and N. nebularum.
New cultivars
Authors: Hummer John , Faulisi Phil , Carlton Hawken , Brittnacher John
Published: February 2022

The cultivars Sarracenia 'Mega Mouth', Sarracenia 'Monks Head Hammerhead', Sarracenia
'Red Beret', Sarracenia 'Tower of Terror', Drosera 'Dr. Frankensnyder's Monster', and Drosera 'Nightmare' are described.
In search of Andean Pinguicula
Authors: Aranoa Danel Josu
Published: February 2022

Observations of Andean Pinguicula species.
The long overdue recognition of Sarracenia rubra subsp. viatorum
Authors: Rice Barry A.
Published: February 2022

The complex of taxa associated with Sarracenia rubra Walter has long been embroiled in controversy, with many scientists having different perspectives on how the plant should be interpreted. In part, this is because the plants have an interesting, patchy distribution throughout the southeastern USA. Sarracenia rubra subsp. viatorum is described.
Possible pollinators for two Japanese Pinguicula species
Authors: Shimai Hiro
Published: February 2022

This short article documents floral visitors or possible pollinators for the flower of two Japanese Pinguicula species, P. macroceras Link and P. ramosa Miyoshi, presumably the first witness to be reported. It is widely believed that those Pinguicula flowers are basically pollinated by insects, but what kinds was previously unknown. The author has confirmed at some natural localities, floral visits of a sweat bee species on a flower of P. macroceras and of hoverflies and ocellate rove beetles on P. ramosa flowers.
Contribution to knowledge of Sarracenia 'Adrian Slack' genetic background
Authors: Srba Miroslav
Published: February 2022

Sarracenia hybridization and genetics have been my interest since early 1990s. A cultivar looking like Sarracenia ‘Adrian Slack’ was my dream plant for a long time; I wanted to create such a plant and name it after my wonderful wife. When I opened the envelope with December issue of CPN in 2000, my jaw just fell to the ground: “Somebody else made it!”. I read immediately that this splendid cultivar was named after Adrian Slack and it is a natural creation in fact. Although it has been nearly 20 years since Sarracenia ‘Adrian Slack’ (ADS later in text) was described, it is still one of the most elegant Sarracenia cultivars.
STUDI KELAYAKAN TEKNIS DAN FINANSIAL PROYEK PEMBANGUNAN PASAR ATAS KOTA BUKITTINGGI SUMATERA BARAT
Authors:   Mahasiswa Manajemen Rekayasa Konstruksi Politeknik Negeri Malang, In Churin , Setiono Joko , Lydianingtias Diah ,   Dosen Jurusan Teknik Sipil Politeknik Negeri Malang,   Dosen Jurusan Teknik Sipil Politeknik Negeri Malang
Published: February 2022

Proyek pembangunan Pasar Atas Kota Bukitinggi Sumatera Barat dengan luas total bangunan 35.445,05 m2 yang terdiri dari empat lantai dan satu basement memerlukan studi kelayakan. Tujuan skripsi ini yaitu menganalisis kelayakan teknis berdasaekan KDB, KLB, KDH, dan GSB sesuai dengan peraturan yang berlaku, menghitung biaya investasi, menghitung pendapatan bangunan, menganalisis kelayakan finansial menggunakan parameter Net Present Value (NPV), Internal Rate of Return (IRR), Benefit Cost Ratio (BCR), dan Payback Period (PP), serta menganalisis sensitivitas untuk mengetahui tingkat sensitivitas terhadap parameter – parameter ynag ditinjau. Data yang diperlukan yaitu gambar teknis, Rencana Anggaran Biaya (RAB), biaya pengadaan lahan, biaya IMB, serta peraturan – peraturan yang digunakan. Hasil analisis kelayakan teknis menunjukkan bahwa pembangunan Pasar Atas Kota Bukittinggi sesuai dan layak dengan peraturan – peraturan yang berlaku, sedangkan hasil analisis kelayakan finansial menunjukkan bahwa pembangunan Pasar Atas Kota Bukittinggi layak (menguntungkan) karena diperoleh hasil perhitungan dengan parameter NPV sebesar Rp 279.292.553.765>0; BCR sebesar 1,7366045≥1; IRR sebesar 10,6624%> MARR; dan PP selama 2 tahun 3 bulan 6 hari < umur rencana investasi yaitu 15 tahun. Hasil analisis sensitivitas menyatakan bahwa faktor penurunan jumlah pengunjung pasar menyebabkan perubahan yang cukup sensitif terhadap kelayakan, sedangkan faktor jumlah kekosongan kios dan los serta kenaikan suku bunga tidak menyebabkan perubahan yang cukup sensitive terhadap kelayakan.
PENGARUH PENAMBAHAN SIKACIM PADA CAMPURAN BETON POROUS UNTUK PERKERASAN JALAN TERHADAP KUAT TEKAN DAN KUAT LENTUR
Authors:   Mahasiswa Manajemen Rekayasa Konstrusi Jurusan Teknik Sipil, Politeknik Negeri Malang, Lestiana Willa Nurhaidar , Marjono  ,   Dosen Jurusan Teknik Sipil, Politeknik Negeri Malang, Qomariah  ,   Dosen Jurusan Teknik Sipil, Politeknik Negeri Malang
Published: February 2022

Pemanfaatan beton porous sebagai lapis perkerasan jalan yang dapat dialiri oleh air merupakan salah satu bentuk alternatif lapis perkerasan yang ekonomis dan ramah lingkungan. Pada penelitian ini campuran beton porous menggunakan semen, agregat kasar dengan gradasi seragam 4,75 mm, air, serta penambahan Sikacim Bonding Adhesive dengan variasi 1:0, 1:0,5, 1:1, 1:1,5, dan 1:2 terhadap kadar air. Tujuan dari penelitian ini untuk mendapatkan data hubungan antara kuat tekan terhadap variasi penambahan Sikacim dan nilai lendutan terhadap beban tekan. Hasil penelitian menunjukkan bahwa adanya penambahan Sikacim pada campuran beton porous dapat meningkatkan nilai kuat tekan serta meningkatkan nilai lendutan, dalam hal ini variasi 1:1,5 adalah yang paling tinggi. Bentuk hubungan antara kuat tekan dengan variasi penambahan Sikacim pada variasi 1:1,5 Y = -89,029 x2 + 211,15 x – 114,87. Y = Kuat tekan (MPa), X = Variasi penambahan Sikacim. Bentuk hubungan antara nilai lendutan terhadap beban tekan Y = 6E – 0,5 x2 – 0,006 x. Y = Besar lendutan (mm), X = Beban tekan (kg). Biaya yang dibutuhkan untuk perkerasan beton porous dengan penambahan Sikacim Bonding Adhesive variasi 1:1,5 sebesar Rp 2.700.000,00/m3
STUDI PENYEMPURNAAN MODEL BATA RINGAN BERKAIT DAN PENGUJIAN STRUKTUR DINDING AKIBAT GESER BIDANG
Authors:   Mahasiswa Program Studi Manajemen Rekayasa Konstruksi, Jurusan Teknik Sipil, Politeknik Negeri Malang, Aditya Yangyang , Rochman Taufiq ,   Dosen Jurusan Teknik Sipil, Politeknik Negeri Malang, Sugiarto Agus ,   Dosen Jurusan Teknik Sipil, Politeknik Negeri Malang
Published: February 2022

Dalam beberapa tahun ini banyak dilakukan penelitian tentang material dinding dan model sambungan pasangan bata yang lebih mudah dan cepat dalam pengerjaan. Dalam penelitian ini dilakukan analisis specific strength dengan metode Taguchi untuk menentukan komposisi yang tepat untuk produksi bata ringan berkait. Sampel awal dalam penelitian ini adalah 16 buah benda uji kubus dengan dimensi 15x15x15 cm. Berdasarkan analisis data menggunakan metode Taguchi dengan menghitung Rata-Rata, menghitung Signal to Noise Ratio (SNR), menghitung Efek Faktor dari Rata-Rata, dan menghitung Efek Faktor dari SNR dapat disimpulkan bahwa semua analisis memperlihatkan hasil yang sama yaitu specific strength akan optimal jika menggunakan rancangan usulan A3, B1, dan C1 yaitu FAS 0,6, konsentrasi foam agent 1:10, dan fiberglass 1% dari berat semen. Berdasarkan hasil perhitungan specific strength, dan hasil perhitungan metode taguchi maka trial yang akan dipilih untuk pembuatan bata ringan berkait adalah Run-12 karena mempunyai specific strength paling tinggi, serta memiliki kesamaan komposisi paling mendekati dengan rancangan usulan yaitu FAS 0,6, konsentrasi foam 1:10, dan fiberglass 2%.
PERENCANAAN ULANG STRUKTUR ATAS RUMAH SUSUN PONDOK BENOWO INDAH (PBI) SURABAYA JAWA TIMUR
Authors:   Mahasiswa Manajemen Rekasaya Konstruksi, Jurusan Teknik Sipil, Politeknik Negeri Malang, Rahmawati Alifiah Devi , Sugiharti  ,   Dosen Jurusan Teknik Sipil, Politeknik Negeri Malang, Utoyo Suselo ,   Dosen Jurusan Teknik Sipil, Politeknik Negeri Malang
Published: February 2022

Perencanaan struktur gedung Rumah Susun Pondok Benowo Indah Surabaya, Jawa Timur. Studi ini bertujuan untuk mencari alternatif ulang yang awalnya perencanaan menggunakan dak beton menjadi rangka baja yang mengacu pada peraturan seperti ketahanan gempa mengacu pada SNI 1726-2012. Perhitungan struktur baja menggunakan metode Load and Resistance Factor Design (LRFD) yang mengacu pada SNI 1729-2015 dan perhitungan struktur beton bertulang mengacu pada SNI 2847-2013 dan SNI 1726-2013. Analisis statika struktur menggunakan program aplikasi komputer Robot Structural Analysis Professional 2018 dan penggambaran hasil perencanaan menggunakan program aplikasi komputer AutoCAD 2018. Hasil dari perencanaan ulang struktur atas dengan menggunakan kuda-kuda rangka baja profil 2L 50.50.5, gording profil Lip Channels 150.50.20.2,3 mm, penggantung gording menggunakan besi polos Ø10, ikatan angin menggunakan besi polos Ø8, serta sambungan baut Ø1/2” d = 12,7 mm, dan sambungan angker 4 Ø 19,05 mm atau 3/4” dengan panjang yang digunakan 12,5 cm. Perencanaan struktur utama didapatkan tebal pelat lantai 12 cm dan Ø10-125. Dimensi balok anak tipe 1 20/40 (3D16 & 2D16), dimensi balok anak tipe 2 20/40 (2D16 & 2D16), dimensi balok melintang dan balok induk memanjang 30/50 (3D16 & 2D16), dimensi sloof 30/50 (2D16 & 3D16), dimensi kolom 40/50 (10D16), dan tebal pelat tangga 15 cm menggunakan D13. Biaya awal dengan menggunakan atap dak sebesar Rp. 9.210.664.000,00 dan setelah dihitung dengan menggunakan atap rangka baja diperoleh nominal sebesar Rp 8.822.943.000,00. Maka penggunaan atap rangka baja lebih ekonomis dibanding atap dak.
OPTIMASI PENGGUNAAN ALAT BERAT PADA PEKERJAAN GALIAN DAN TIMBUNAN PROYEK PEMBANGUNAN KOLAM REGULASI NIPA – NIPA MAKASSAR
Authors:   Mahasiswa Manajemen Rekayasa Konstruksi Politeknik Negeri Malang, Asshiddiqie Hafizh , Khamim Moch. ,   Dosen Jurusan Teknik Sipil Politeknik Negeri Malang, Setiono Joko ,   Dosen Jurusan Teknik Sipil Politeknik Negeri Malang
Published: February 2022

Kolam regulasi dibangun di samping sungai Tello yang memiliki luas 85 ha dan volume tampungan 3,58 juta m3. Agar elevasi sesuai dengan perencanaan diperlukan adanya galian. Perlu juga timbunan untuk pembuatan tanggul kolam. Penggunaan alat berat harus dianalisa agar optimal, yaitu mencapai biaya minimum tanpa mengabaikan target waktu yang akan dicapai. Metode yang digunakan untuk mendapatkan hasil optimum menggunakan metode program linier. Data yang digunakan adalah spesifikasi alat berat, gambar potongan melintang, harga sewa alat berat, jadwal pekerjaan dan volume total pekerjaan galian dan timbunan. Hasil optimasi menunjukkan kebutuhan alat berat dan biaya operasional yang optimum pada setiap alternatif kombinasi. Pada pekerjaan timbunan zona 1 dipilih kombinasi 5 dengan biaya total Rp 1.167.311.664 dengan komposisi 1 unit excavator, 3 unit dump truck, 1 unit bulldozer, 1 unit vibro roller, dan 1 unit water tank truck. Pada zona 2 dipilih kombinasi 3 dengan biaya total Rp 2.038.195.328 dengan komposisi 3 unit excavator, 3 unit dump truck, 2 unit bulldozer, 2 unit vibro roller, dan 2 unit water tank truck. Untuk pekerjaan galian zona 1 dipilih kombinasi 8 dengan biaya Rp 18.261.494.400 dengan komposisi 2 unit excavator, 4 unit dump truck, 4 unit bulldozer. Pada zona 2 pekerjaan galian dipilih kombinasi 8 dengan biaya total Rp 26.290.907.200 dengan komposisi 3 unit excavator, 7 unit dump truck, 4 unit bulldozer.
What’s the matter with |U| and |I|?
Authors: Pimenta Heglyn
Published: February 2022

In Element-Theory and similar approaches to the internal structure of segments, it is often assumed that the aperture element |A| is more sonorous and different in kind from the coloring elements |I| and |U| (Hulst 2015; Pöchtrager 2006; Schane 1984), while the latter are usually considered to be equally sonorous and display symmetrical behavior. As it has been previously noted, though, this formulation misses a recurrent crosslinguistic asymmetry. |I| and |U| do in fact have distinct behaviors (Carvalho & Klein 1996, Nevins 2012, Veloso 2013, Pimenta 2019), and while typologically, rounding can be absent from a language inventory, “no language has been found that lacks both a front vowel and palatal glide” (Hyman 2008: 100, n. 11). As will be shown, this asymmetry is the source of several phenomena in Portuguese phonology, both synchronic and diachronic. Special attention will be given to nasal vowel diphthongization in non-standard European Portuguese, which reveals a preference for the front offglide over the back offglide, [j] appearing even in some contexts where [w] would be expected. This preference, as will be argued, has its origin in sonority asymmetry, |I| being less sonorous than |U|.
Persons and Pronouns: Exploring Clitics in Judeo-Spanish
Authors: Kurtz Naomi
Published: February 2022

Optional versus obligatory clitic doubling and the person-case constraint (PCC) repair constitute two puzzles researchers haven’t fully addressed. In Judeo-Spanish, doubling is obligatory for third person accusative strong pronouns; for all other arguments, doubling is optional. This analysis contends arguments are generated with corresponding clitics in the syntax. The realization of clitics is regulated by functional heads: v and X, a head located beneath v. X is hypothesized to be a probe specified only for person; critically, third person accusative strong pronouns lack person features (Anagnostopoulou 2003), while other arguments bear person features. Optional doubling is regulated by alternations in Agree with v or X. An argument that appears without a co-referring clitic is derived via agreement with X. This interaction triggers deletion of clitics’ phi-features, which causes them to be null. Overt cliticization is derived via agreement with v. Obligatory doubling is derived via Agree strictly with v; third person accusative strong pronouns cannot be potential goals for X since they lack person features. Apart from doubling, X generates the PCC repair by blocking Agree between v and dative clitics, causing dative arguments to appear without a matching clitic, and by eliminating intervention effects between v and accusative clitics
Vitamin E Extraction from Magnesium Salts of Palm Fatty Acid Distillates
Authors: Lestari Dianika , Aqilah Khalisa Putri , Putri Salsafia , Harimawan Ardiyan , Mudhakir Diky , Insanu Muhamad
Published: February 2022

This research studied how the type of organic solvent and the number of extraction stages affect the vitamin E cumulative extraction yield and recovery rate from Mg-PFAD. First, PFAD was saponified to produce Mg-PFAD, then vitamin E was extracted from the Mg-PFAD using ethanol, isopropanol, or hexane, followed by evaporation to produce vitamin E concentrate. Three-stage hexane extraction with a solvent to Mg-PFAD mass ratio of 3 kg solvent/kg Mg-PFAD produced the highest vitamin E recovery rate. Organic solvent with a lower polarity gave a higher extraction yield and recovery rate of vitamin E from Mg-PFAD. In general, an increase of the number of extraction stages led to an increase of the vitamin E extraction yield and recovery rate from Mg-PFAD.
Analisis Kadar Hepcidin Pada Obesitas Sentral dan Non Obesitas Sentral
Authors: Rasyid Ida Mawadda
Published: February 2022

Obesitas telah menjadi permasalahan dunia bahkan World Health Organization (WHO) mendeklarasikan obesitas sebagai masalah epidemik. Obesitas sentral adalah penumpukan lemak dalam tubuh bagian perut yang dapat diukur dengan menggunakan indikator Lingkar Pinggang (LP). Salah satu dampak yang dapat terjadi akibat obesitas sentral adalah penurunan kadar besi dalam tubuh. Hepcidin merupakan pengatur utama homeostasis zat besi secara sistemik. Tujuan penelitian untuk menganalisis kadar hepcidin pada obesitas sentral dan non obesitas sentral. Telah dilakukan penelitian dengan desain penelitian cross-sectional. Subjek merupakan laki-laki dan perempuan usia ≥18–40 tahun dan memenuhi kriteria inklusi. Hasil analisis statistik menunjukkan tidak terdapat perbedaan yang bermakna dari kadar hepcidin kelompok obesitas sentral dan non obesitas sentral (p=0,142). Hasil uji korelasi Sperman menunjukkan tidak terdapat korelasi yang bermakna antara LP dengan hepcidin (r=0,076, p=0,643). Kesimpulan tidak terdapat perbedaan bermakna kadar hepcidin antara subjek obesitas sentral dibandingkan dengan subjek non obesitas sentral dan tidak terdapat korelasi bermakna antara LP dengan kadar hepcidin pada subjek dengan obesitas sentral.
Mid-Atlantic English in the EFL Context
Authors: Mering Andy
Published: February 2022

This book examines the increasing usage of a mixture of British and American English in the EFL context, Mid-Atlantic English. The book has three parts. The theoretical part provides extensive background information on the sociolinguistic and didactic role of British and American English in ELT. The empirical part offers a large-scale questionnaire-based study carried out with an important EFL community and UK native-speakers. It investigates participants’ linguistic Americanisation and their attitudes to the two main varieties of English. The didactic part suggests integrating a pluricentric vision into EFL settings through multiple tasks. This book shows that ELT needs rethinking because of the international Americanisation of the English language.
Association between sleep insufficiency and dyslipidemia: a cross-sectional study among Greek adults in the primary care setting
Authors: Tsiptsios Dimitrios , Leontidou Eleni , Fountoulakis Petros N. , Ouranidis Andreas , Matziridis Anestis , Manolis Apostolos , Triantafyllis Andreas S. , Tsamakis Konstantinos , Serdari Aspasia , Terzoudi Aikaterini , Dragioti Elena , Steiropoulos Paschalis , Tripsianis Gregory
Published: February 2022

Objective To investigate the potential association between sleep insufficiency and dyslipidemia (DL) in the primary care setting using self-reported questionnaires.

Material and Methods 957 adults aged between 19 and 86 years old from the rural area of Thrace, Greece were enrolled in this cross-sectional study. Multistage stratifed cluster sampling was used and the subjects were classifed into three groups according to sleep duration [short (<6h), normal (6-8h), and long (>8h) sleep duration]. DL was defined by a positive response to the question “Have you ever been told by a doctor or health professional that your blood cholesterol or triglyceride levels were high?”, or if they were currently taking antilipidemic agents. Sleep quality, utilizing Epworth sleepiness scale, Athens insomnia scale, Pittsburgh sleep quality index and Berlin questionnaire, was also examined.

Results DL prevalence was significantly associated with short sleep duration (aOR=2.18, p<0.001) and insomnia (aOR=1.43, p=0.050), while its relation with poor sleep quality (aOR=1.31, p=0.094) and risk for obstructive sleep apnea (aOR=1.32, p=0.097) were of marginal statistical significance. Concerning insomnia subtypes, DL was significantly associated with difficulties maintaining sleep (aOR=2.99, p<0.001) and early morning awakenings (aOR=1.38, p=0.050), but not difficulties initiating sleep (aOR=1.18, p=0.328).

Conclusion This study reveals an association between sleep pathology and DL. Thus, early pharmacological and cognitive or behavioral interventions that improve sleep are deemed necessary in order to decrease DL burden.
Changes in adolescents’ sleep during COVID-19 outbreak reveal the inadequacy of early morning school schedules
Authors: Santos Jefferson Souza , Louzada Fernando Mazzilli
Published: February 2022

Objectives The forced closure of schools during the COVID-19 outbreak imposed on adolescents a new reality of home-schooling. This new situation has affected adolescent sleep patterns due to the absence of the pressure to wake up earlier induced by school times during pandemic. This study aimed to investigate the changes in sleep and napping habits in Brazilian adolescents during the COVID-19 outbreak.

Methods A sample of 259 high school adolescents (mean age = 15.5 years) reported sleep and napping habits by means validated questionnaires in both baseline year (March-June 2019) and during COVID-19 lockdown (July 2020).

Results The tendency to eveningness was higher and daytime sleepiness was reduced during the social isolation. Time in bed (TIB) increased by more than 2 hours and sleep onset time was delayed during the pandemic. More adolescents reported getting enough TIB during the pandemic. Moreover, sleepiness during remote classes was reduced compared to that reported during traditional classes one year before. The nap habit decreased during the pandemic compared to the baseline year.

Discussion The lack of early wake-up pressure to attend school in the morning could explain the sleep improvements perceived during the COVID-19 outbreak. Therefore, parents, educators, and policy makers need to discuss more feasible school times for adolescents in order to implement these changes as soon as returning to presential/hybrid learning.
Prevalence of predictive factors for obstructive sleep apnea in university students
Authors: Santos Eduardo Rodrigues dos , Silva Jamilly Henrique Costa da , Lima Anna Myrna Jaguaribe , Studart-Pereira Luciana Moraes
Published: February 2022

Objectives To identify predictive factors for obstructive sleep apnea in university students.

Material and Methods Analytical, observational, cross-sectional study, conducted from August 2018 to February 2019. 144 students of both genders, informed of purposes and procedures, signed consent forms to participate. Procedures included measuring body mass index, abdominal, and neck circumference; inspecting tongue and oropharynx with Mallampati modified classification; answering Berlin questionnaire.

Results 63.9% had normal body mass index; 19.4% were overweight. 59.7% had normal abdominal circumference; 89.6%, normal neck circumference. 65.3% presented Mallampati class I V. 74.3% indicated no obstructive sleep apnea; 25.7% were at high risk. High risk for obstructive sleep apnea associated with body mass index (p<0.001), abdominal (p=0.006), and neck circumference (p<0.001).

Discussion Anthropometries were mostly normal, despite the high prevalence of changed Mallampati classification. Positively correlated predictive factors, also associated with high risk for obstructive sleep apnea, reinforce the need for such preventive measures in youth.
The cardiovascular, metabolic, fetal and neonatal effects of CPAP use in pregnant women: a systematic review
Authors: Migueis Debora Petrungaro , Urel Arthur , Santos Camila Curado dos , Accetta Andre , Burla Marcelo
Published: February 2022

Continuous positive airway pressure (CPAP) is the standard treatment for obstructive sleep apnea (OSA), but its outcomes for the pregnant are still undefined. This study aims to review current CPAP intervention during pregnancy, discuss published trials, and propose relevant issues that have yet to be addressed satisfactorily about the cardiovascular, metabolic, fetal, and neonatal effects of CPAP treatment during gestation. Two authors independently conducted a systematic review until March 28th, 2021 on PubMed, BVS, and Cochrane Library, using PRISMA guidelines, and risk of bias. Discrepancies were reconciled by a third reviewer. Of 59 identified citations, eight original trials have submitted a total of 90 pregnant women to polysomnography and CPAP therapy. Four studies performed in samples with hypertension or preeclampsia presented blood pressure decrease or maintained the antihypertensive drug dose in the CPAP group. After CPAP utilization, one trial registered cardiac output and stroke volume increase with heart rate and peripheral vascular resistance decrease, which were correlated with birth weight increment. Others documented a higher Apgar in the CPAP group and more fetal movements during CPAP use. There was a reduction in serum uric acid and tumor necrosis factor-alpha in the CPAP groups whose blood pressure decreased. However, two weeks of CPAP use in women with gestational diabetes and OSA did not improve glucose levels but raised the insulin secretion in those adherents to CPAP. Despite these positive results without adverse effects, randomized controlled trials with standardized follow-up in larger populations are required to determine CPAP therapy recommendations in pregnancy.