bluuebunny/crossref_metadata_2025 huggingface dataset:
Medullary Thyroid Cancer with Paraganglioma-Like Pattern Diagnosed During Pregnancy: A Case Report and Literature Revision
Authors: De Tullio Anna , Lisco Giuseppe , Duda Loren , Renzulli Giuseppina , Triggiani Vincenzo
Published: August 2019

Introduction:

Medullary thyroid carcinoma (MTC) is an infrequent thyroid malignancy
rarely observed and managed during pregnancy. An accurate diagnostic workup is extremely important
in this clinical setting to correctly diagnose and treat the disease, avoiding both maternal and fetal complications.

Objective:

We report our experience in managing an MTC incidentally diagnosed during pregnancy in
a 28-year female, highlighting critical aspects through the diagnostic workup. Additionally, we provide
a literature revision searching on PubMed terms related to “medullary thyroid carcinoma”, “primary
thyroid paraganglioma”, “paraganglioma-like medullary thyroid cancer” in relationship with a nodular
appearance at neck US, serum CT measurement, cytological and histological findings.

Methods:

Specimens for cytological evaluation were stained with the Papanicolaou method while tissue
sections were stained with hematoxylin and eosin and Congo red stain. Immunohistochemical
evaluation was also performed for thyroid transcription factor-1, enolase, thyroglobulin, cytokeratin,
chromogranin A, S-100 protein, glial fibrillary acidic protein, calcitonin and Ki-67.

Results:

Serum CT was incidentally found to be elevated in two consecutive venous samples. However,
the cytological assessment of the fine needle aspiration (FNAc) showed “cells with round-shaped
nuclei and granular chromatin, organized to form nests or syncytial flaps, scattered among histocytes,
and immunocytochemical positivity for CT, thyroid transcriptional factor-1, cytokeratin, S-100 protein”,
highlighting a suspicion of both MTC and intrathyroidal paraganglioma. MTC was finally supposed
after the evidence of a really elevated CT (3,726 pg/ml) measurement in the FNA washout fluid.
After a careful discussion about both risks and benefits, the patient decided to postpone the surgery
after the delivery.

Conclusion:

The histological diagnosis finally confirmed a rare case of paraganglioma-like MTC (T1
N0 Mx), emphasizing the complexity of our differential diagnosis, between an MTC and a thyroidal
paraganglioma. In similar cases, due to a relevant impact on surgical timing, patients should be adequately
informed about both risk and benefits of the surgery during pregnancy, and a careful management
of the disease is required until and after surgery.
Evaluation of Gene Expression and In Vitro Enzyme Study for Antiaging Effect of Crocin and Lutein
Authors: Naik Archana A. , Gadgoli Chhaya H. , Naik Arvind B.
Published: August 2019

Background:

Tubular calyx of flowers of Nyctanthes arbour-tristis contains an apocarotenoid
crocin, a major constituent present in saffron stigma. The flowers of N. arbortristis are readily
available, hence can be an economic substitute for saffron. Lutein from flowers of Tagetes patula, is
another carotenoid which is a popular antioxidant.

Objective:

Oxidative stress is a major contributor to the process of aging. Carotenoids are powerful
antioxidants. Hence, the study was carried out to evaluate anticollagenase activity and antielastase
activity using gene expression study in Human dermal fibroblasts.

Methods:

Crocin was isolated from the tubular calyx of Nyctanthes arbortristis using flash chromatographic
technique and lutein was isolated using column chromatography. Anticollagenase and antielastase
activity of crocin and lutein were carried out using collagenase from Clostridium
histolyticum as enzyme and porcine pancreatic elastase. Cytotoxicity of crocin and lutein was determined
in Human Dermal Fibroblast cell line (HDF) through MTT assay. In gene expression study,
the HDF Cell line was inoculated with Crocin (450 and 250 ppm) and lutein (100 and 50 ppm) separately
for 24 hrs and the m-RNA expression levels of COL Type-1 and elastin were determined using
RT-PCR. The results were compared with standards.

Result:

Crocin and lutein both showed inhibition of collagenase and elastase enzyme which are responsible
for aging process. The cytotoxic concentration CTC 50 (ppm) for Crocin and lutein was
found to be 790.2 ppm and 137.14 ppm. Gene expression study on crocin rich extract of Nyctanthes
arbortristis showed upregulation of both collagen and elastin gene whereas lutein rich extract having
concentration100 μg/ml showed up regulation by 0.02 fold and concentration 50 μg/ml showed
down regulation.

Conclusion:

In vitro collagenase and elastase enzyme study and Gene expression study showed that
these carotenoids are potential antiageing agents which can be substituted to synthetic cosmeceuticals
as well as saffron.
Sertraline Associated with REM Sleep Behavior Disorder: A Case Report
Authors: Mansouripour Seyed Mostafa , Kumar Dharmendra
Published: August 2019

Background:

REM sleep behavior disorder (RBD) is manifested by abnormal
motor behavior with an endurance of tone during REM sleep. Studies suggest that patients
taking Selective serotonin reuptake inhibitors (SSRIs) are at greater risk of developing
REM sleep behavior disorder.

Case Presentation:

We present a case of 39-year-old female with a past medical history of
spinal cord injury from a gunshot wound 19 years ago resulting in paraplegia, posttraumatic
stress disorder(PTSD), chronic pain, and chronic sleep problem. After sertraline
started and up-titrated to 200 mg for her anxiety, she noticed worsening of her nighttime
sleep behavior. Her mother also witnessed sleepwalking episode and doing things which
the patient had no recollection in the morning, including trying to take a bath and eat from
the refrigerator. On her follow-up appointment, her sertraline was discontinued altogether
and she was started on Escitalopram 5 mg. She tolerated the medication well, it helped
moderately with her anxiety and by the time of this case report (approximately 1 month)
patient did not report any sleep-related behavior.

Conclusion:

Since antidepressant medication is very commonly prescribed, it is important
to be cautious of physiologic changes they may induce, even if the clinical significance of
these changes is not fully elucidated. In addition, RBD may predict neurodegenerative disorders
a couple of years earlier, so it may be used as an effective early marker of neurodegenerative
diseases.
Solid Lipid Nanoparticles of Dronedarone Hydrochloride for Oral Delivery: Optimization, In Vivo Pharmacokinetics and Uptake Studies
Authors: Gambhire Vaishali M. , Gambhire Makarand S. , Ranpise Nisharani S.
Published: August 2019

Background:

Dronedarone HCl (DRD), owing to its poor aqueous solubility
and extensive presystemic metabolism shows low oral bioavailability of about 4% without
food, which increases to approximately 15% when administered with a high fat meal.

Objective:

Solid lipid nanoparticles (SLN) were designed with glyceryl monstearate
(GMS) in order to improve oral bioavailability of DRD.

Methods:

Hot homogenization followed by probe sonication was used to prepare SLN dispersions.
Box-Behnken design was used to optimize manufacturing conditions. SLN were
characterized for particle size, zeta potential, entrapment efficiency, physical state and in
vitro drug release. Pharmacokinetics and intestinal uptake study of dronedarone HCl loaded
solid lipid nanoparticles (DRD-SLN) in the presence and absence of endocytic uptake
inhibitor, chlorpromazine (CPZ) was performed with conscious male Wistar rats.

Results:

Optimized formulation of SLN showed particle size of 233 ± 42 nm and entrapment
efficiency of 87.4 ± 1.29%. Results of pharmacokinetic studies revealed enhancement
of bioavailability of DRD by 2.68 folds from SLN as compared to DRD suspension. Significantly
reduced bioavailability of DRD-SLNs in the presence of chlorpromazine,
demonstrated the role of endocytosis in uptake of SLN formulation.

Conclusion:

These results indicated that dronedarone HCl loaded SLN could potentially
be exploited as a delivery system for improving oral bioavailability by minimizing first
pass metabolism.
Formulation and Pharmacokinetic Evaluation of Phosal Based Zaltoprofen Solid Self-Nanoemulsifying Drug Delivery System
Authors: Kalamkar Rajan , Wadher Shailesh
Published: August 2019

Background:

Phosal based excipients are liquid concentrates containing phospholipids.
They are used to solubilize water-insoluble drug and also act as an emulsifier to
get the smallest droplet size of the formed emulsion after administration.

Objective:

The aim is to prepare phosal based self nanoemulsifying drug delivery system
(SNEDDS) for water insoluble drug zaltoprofen.

Methods:

The various parameters like solubility of drug in different vehicles, ternary phase
diagram are considered to formulate the stable emulsion which is further characterized by
Self emulsification time and globule size analysis to optimize liquid SNEDDS of Zaltoprofen.
Optimized L-SNEDDS was converted into free-flowing powder Solid-SNEDDS
(S-SNEDDS). S-SNEDDS was evaluated for Globule size analysis after reconstitution, in
vitro dissolution study and in vivo pharmacokinetic study in rats.

Results:

Phosal 53 MCT with highest drug solubility was used as oil along with Tween 80
and PEG 400 as surfactant and cosurfactant respectively to prepare liquid SNEDDS. Neusilin
us2 was used as an adsorbent to get free-flowing S-SNEDDS. S-SNEDDS showed
improved dissolution profile of the drug as compared to pure drug. In vivo study demonstrated
that there is a significant increase in Cmax and AUC of S-SNEDDS compared to
zaltoprofen powder.

Conclusion:

Phosal based SNEDDS formation can be successfully used to improve the
dissolution and oral bioavailability of poorly soluble drug zaltoprofen.
Fuzzy and Neuro Fuzzy Based Iterative Image Fusion
Authors: Dammavalam Srinivasa Rao , Aljawarneh Shadi A. , Rajasekhar N.
Published: August 2019

Image fusion is to converge Multispectral (MS) and Panchromatic (PAN) images into a fused image which is further enlightened. Soft computing based image fusion techniques are fuzzy and neuro-fuzzy are exploited to lessening the severance and vagueness in the output. Fused images achieved after the synthesis is utilized in image analysis, medical applications, armed province, and computer revelation. In this research, we convey iterative image fusion based on fuzzy and neuro-fuzzy methods on source images attained from different sources to improve visualization proficiency. We also compared the proposed techniques with principal component analysis (PCA) and wavelets transform based image fusion. Fused outcomes accomplished from image fusion methods are assessed through typical eminence evaluation parameters. The resulting outcome obtained from iterative fusion is improved in terms of spectral and spatial information when compared to the one-time fused image. Due to neural networks structure, applied sorts of biological neural networks and potentiality of the fuzzy and neuro-fuzzy logic, the proposed method overtakes the conventional methods. The complete investigational consequences formed from anticipated methodology established that the utilization of proposed approaches enhanced image content.
Achieving physical and spiritual happiness on bhakti yoga
Authors: Artana I Wayan , Suda I Ketut , Winaja I Wayan
Published: August 2019

The current paper discussed two points of view, namely; first, analyze critically the methods used to internalize bhakti yoga devotion to followers. Second, to critically analyze the implications that have arisen after the establishment of bhakti yoga ideology. These are very interesting to study because practically bhakti yoga provides “convenience” in achieving physical and spiritual happiness. That is, taking a way that does not twist can accelerate to religion destination, namely the achievement of physical and spiritual happiness. The results showed first, the process of understanding bhakti yoga ideology was carried out by (1) through nawa widha bhakti, (2) hermitage, (3) raising cattle, (4) associating with spiritual teachers (sadhu sangga). Second, the ingrained bhakti yoga ideology has implications for religious life, namely the use of symbols of religious sect identity unlike the use of japamala and tilaka. Implications to socio-culture, there is an interaction of follower’s culture before and after they take part in bhakti yoga in religious sects. The implication for the economy of religious sects and followers is a capital exchange between followers and capital accumulation on followers and organizations.
Profile of relative strength among various weight categories of senior national women weightlifters
Authors: Peter V. F. , Raza Suhel
Published: August 2019

The purpose of this study was purposively selected from the “Senior National Championship for the year 2018. Only women weightlifters participated in various weight categories, acted as the subjects. The age of the subjects ranged from 18-34 years. The total subjects were N=54, which were divided into three (3) groups of eighteen (18) subjects for each group. The first groups were low weight categories (48 kg. & 53 kg.), Second groups were middleweight categories (63 kg, 69 kg.) and third groups were upper group weight categories (90 kg, +90 kg.). In order to measure the relative strength of various lifters of different groups, the data was collected from the results of “Senior National Championship” Mangalore, Karnataka 21st to 25 January 2018. Descriptive Statistic (Mean, Standard Deviation), One-way, ANOVA (Analysis of variance) with post hoc test (LSD) was applied to analyze and compare the relative strength among the different body weight categories. The level of significance was set at 0.05. 3 indicate that there were significant differences in the entire three groups. However, group Lower had higher relative strength. After applying the post Hoc Test (LSD) it was found that there was a significant difference in all three groups in their relative strength.
The Procedural Issues after the Implementation of Development Charge in Malaysia
Authors: Abd Rahman Nor Azalina Yusnita , Mohamed Saraf Mohamad Haizam , Che Pin Siti Fairuz , Maaruf Muhamad Aiman
Published: August 2019

The development charge is levied to developers if the project is approved for either the conversion of land use, the increment of plot ratios or density, which increases the land value. To date, seven (7) states have implemented the development charges at their local authorities. Each state has a different interpretation of the policy, framework and development charges practices. An interview using a focus group was conducted to identify issues after the implementation of the development charges. Eight (8) local authorities were selected as research samples. Findings from the focus group have discovered five (5) main issues; namely duration, the collection of data, individual application, payment method, and unstandardized rate. Keywords: work procedure, development charge, local governments, issues and challenges.Keywords: Procedural Issues; Development ChargeeISSN: 2398-4287 © 2019. The Authors. Published for AMER ABRA cE-Bs by e-International Publishing House, Ltd., UK. This is an open access article under the CC BYNC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia.DOI: https://doi.org/10.21834/e-bpj.v4i11.1668
The Importance of Ergonomics on Urban Squares: Case from Istanbul
Authors: Turkyilmaz Cigdem Canbay
Published: August 2019

There is a close relationship between the creation of urban spaces and ergonomics. To make new stimulating and satisfying urban spaces, ergonomics criteria should consider. In this study, two main urban squares from Istanbul examined. Selected urban squares evaluated by site observation according to the classified ergonomics criteria. Strong and weak points of chosen squares discussed and some suggestions proposed. The results demonstrated the fact that urban equipment meets the individual ergonomic criteria are not sufficient in the use of both squares, and they need to be re-planned.Keywords: Ergomomics; urban squares, IstanbuleISSN: 2398-4287 © 2019. The Authors. Published for AMER ABRA cE-Bs by e-International Publishing House, Ltd., UK. This is an open access article under the CC BYNC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia.DOI: https://doi.org/10.21834/e-bpj.v4i11.1695 .
Adaptation and Validation of The Children’s Worlds Subjective Well-Being Scale (CW-SWBS) in Indonesia
Authors: Borualogo Ihsana Sabriani , Casas Ferran
Published: August 2019

The Indonesian research team participating in the Children’s Worlds international project has used a new context-free multi-item scale named CW-SWBS (Children’s Worlds Subjective Well-Being Scale). This psychometric instrument was previously never used in Indonesia. This study aimed to validate the adapted Indonesia language version for a representative sample of children who are elementary students in West Java province (N = 22,616), ranging from 8, 10, to 12-year-olds. Confirmatory Factor Analysis (CFA) was used to test the fit of the psychometric scale, and multi-group CFA was used to check the comparability between answers given by gender and school types. Result findings showed that the instrument displays excellent fit for measuring life satisfaction in Indonesian children using five items, instead of the six original items. Answers to the items of the CW-SWBS by gender and school types were demonstrated to be comparable, suggesting that there was no different answering style between individuals in these studied groups.
The Effect of Financial Sector Reforms on Bank Net Interest Margins in Ghana
Authors: Cornerstone Elvis
Published: August 2019

This paper examines the effect of financial sector reforms on net interest margin of Ghanaian banks during the period 1997-2006. Changes have taken place in Ghana as in other countries. However, net interest margins have not declined as much in Ghana as they have elsewhere due to the influence of the degree of risk aversion, high operating costs and uncompetitive nature of the market structure. Although banks have relied heavily on fee- and commission-based services as additional sources of income to lower margins, this paper argues that despite recent developments in the Ghanaian financial landscape, financial sector reforms have not yet succeeded in bringing about a major reduction in the operating costs of banks that would translate into substantially narrower margins. This is by far the major significant effect of relatively wide net interest margin in Ghana.
Teoria de autodeterminação utilizada em mundos virtuais, um estudo de caso.
Authors: Santiago Sgobbi Fabiana , Margarida Rockenbach Tarouco Liane
Published: August 2019

Esta pesquisa investigou o impacto da combinação de mundos virtuais 3D comdispositivos móveis, agentes conversacionais e sensor de movimentação, como elementos capazes de promover a motivação de sujeitos envolvidos em um programa de controle de obesidade, fator de alta relevância uma vez que o tratamento personalizado tem alto custo e a obesidade é um problema mundial. Este conjunto de tecnologias foi utilizado como estratégia de apoio com vistas a oferecer ao usuário a sensação de “estar presente” num contexto especialmente preparado para promover a motivação e aprendizagem com a interação com objetos 3D. Este traz um recorte sobre a teoria da autodeterminação e como pode ser trabalhada com os dispositivos de Internet das coisas e agentes conversacionais em mundo virtuais.
THE GROWTH OF KIWI SHOOT (ACTINIDIA DELICIOSA) ON VARIOUS KINDS OF GELLING AGENTS
Authors: Mardiana Mardiana , Zainuddin Zainuddin , Mahfudz Mahfudz , Hawalina Hawalina
Published: August 2019

Kiwi fruit takes about 25 weeks from flower bloom until it reaches physiological maturity, so the time required to produce kiwi seeds from seeds in large quantities and uniform is very long. Tissue culture is one method that can be used to obtain a lot of kiwi seeds and uniforms with large quantities in a faster time. The purpose of this study was to examine various types of media compaction materials for the growth of kiwi shoots in vitro. This study was prepared based on Completely Randomized Design (RAL) with 5 treatments and repeated 4 times so that there were 20 experimental units, each experiment using 2 explants so that there are 40 eksplan. The treatments were: MA 1: Agar Swallow Globe 8 g / l, MA 2: Agar Swallow Globe 4 g / l + Agar Nutrijell 4 g / l, MA 3: Agar Swallow Globe 4 g / l + Agar Nutrijell 5 g / l, MA 4: Phytagel 2.2 g / l, MA 5: Agar Nutrijell 11 g / l. Observation variables are When shoots appear, Number of shoots, number of leaves, Number of Roots, number of root hair. The results showed Swallow Globe 4 g / l + Agar Nutrijell 4 g / l treatment gave the highest average number of shoots, the highest number of leaves and roots, this proved that the combination of Swallow Globe and Nutrijell agar gave a good condition for shoot growth kiwi plant.t.
PENERAPAN MODEL PEMBELAJARAN KOOPERATIF TIPE PICTURE AND PICTURE UNTUK MENINGKATKAN MOTIVASI DAN HASIL BELAJAR PADA MATA PELAJARAN TIK DI SMP NEGERI 3 SERIRIT
Authors: Ariana Komang Mas , Agustini Ketut , Sindu I Gede Partha
Published: August 2019

Penelitian ini bertujuan untuk menganalisis peningkatan motivasi dan hasil belajar siswa pada mata pelajaran TIK kelas VIII B semester ganjil 2017/2018 di  SMP Negeri 3 Seririt melalui penerapan model pembelajaran kooperatif  tipe Picture and Picture. Jenis penelitian merupakan penelitian tindakan kelas. Subjek penelitian adalah siswa kelas VIII B sebanyak 30 orang siswa. Objek penelitian adalah model pembelajaran kooperatif  tipe Picture and Picture, motivasi dan hasil belajar. Penelitian ini dilaksanakan dalam dua siklus. Data motivasi belajar dikumpulkan dengan angket dan data hasil belajar dikumpulkan dengan tes. Data penelitian dianalisis secara deskriptif. Hasil analisis data menunjukkan 1) motivasi belajar siklus I dan II berada pada kategori positif. 2) Hasil belajar siswa pada siklus I berada pada kategori sedang, dan pada siklus II berada pada kategori baik. Penerapan model pembelajaran kooperatif tipe Picture and Picture dapat meningkatkan motivasi dan hasil belajar siswa kelas VIII B tahun pelajaran 2017/2018.
PEMANFAATAN ALGORITMA GENETIKA UNTUK MEMBANGUN KOMBINASI PARALEL RESISTANSI YANG SETARA DENGAN RESISTANSI RUSAK
Authors: Untoro F.X. Wisnu Yudo
Published: August 2019

Dalam kurun waktu tertentu barang elektronik akan mengalami kerusakan. Kerusakan ini disebabkan adanya komponen elektronik yang tidak bekerja dengan semestinya. Salah satu komponen elektronik yang bisa rusak ini adalah resistor. Di sisi penyedia jasa service barang elektronik, ketersediaan komponen resistornya cukup terbatas. Terbatasnya ketersediaan resistor ini dapat menimbulkan masalah bila resistansi dari barang elektronik yang rusak tidak tersedia. Memperhatikan hal tersebut usulan penelitian ini adalah pencarian resistansi yang rusak melalui data ketersediaan resistor menggunakan algpritma genetika. Dalam usulan ini, masukan nilai resistansi rusak akan memberikan luaran berupa kombinasi paralel resistansi yang semiliritas dengan resistansi yang rusak. Penerapan parameter probabilitas crossover 0.9 dan pobabilitas mutasi 0.1, algoritma genetika telah mampu memberikan hasil kombinasi paralel resistansi yabg setara dengan resistansi rusak.
PEMETAAN ANIMO PESERTA DIDIK SMK NEGERI PRODI KEAHLIAN TEKNIK KOMPUTER DAN INFORMATIKA SE-KOTA MALANG UNTUK MELANJUTKAN STUDI KE PERGURUAN TINGGI DENGAN PRODI YANG SEBIDANG
Authors: Irawan Anggi Kusuma , Sutikno Tri Atmadji , Wirawan I Made
Published: August 2019

Lulusan Sekolah Menengah Kejuruan (SMK) bisa melanjutkan ke perguruan tinggi tidak hanya lulusan Sekolah Menengah Atas (SMA) saja. Peserta didik SMK dapat mengembangkan potensi di perguruan tinggi dengan prodi yang sesuai dengan jurusan yang digeluti untuk menjadi teknisi yang handal dibidangnya. Dalam penelitian ini terdapat seberapa besar animo peserta didik SMK prodi keahlian teknik komputer dan informatika untuk melanjutkan studi ke perguruan tinggi dengan prodi yang sebidang serta faktor internal dan eksternal yang mempengaruhinya. Penelitian ini dilakukan pada peserta didik SMK Negeri prodi keahlian teknik komputer dan informatika kelas 12 tahun ajaran 2018/2019 Se-Kota Malang dengan jumlah sampel 559 peserta didik dan menggunakan analisis statistik deskriptif. Hasil analis yang dilakukan berhasil mendapatkan 72,63% peserta didik ingin melanjutkan ke perguruan tinggi dan 27,37% memilih untuk tidak melanjutkan. Kecenderungan animo peserta didik yang ingin melanjutkan perguruan tinggi berada pada kategori tinggi yaitu 56,15%. Presentase skor faktor yang mempengaruhi yaitu, faktor dari dalam diri sendiri 82,53% berada pada kategori sangat tinggi, faktor lingkungan keluarga 79,58% berada pada kategori tinggi, dan faktor lingkungan sekolah 74,62% berada pada kategori tinggi. Kemudian sebanyak 70,93% peserta didik memilih prodi yang sebidang. Penelitian ini berhasil mengungkap: (1) Kecenderungan animo berada pada kategori tinggi; (2) presentase skor faktor dalam diri sendiri lebih besar; (3) sebagian besar memilih prodi yang sebidang; (4) prodi teknik informatika paling banyak diminati.
Pengembangan Aplikasi Virtual Reality 3D Pengenalan Manusia Purba Bangsa Indonesia untuk SMA Kelas X (Studi Kasus SMA Negeri 2 Singaraja)
Authors: Wardhana Nyoman Jaya , Arthana I Ketut Resika , Divayana Dewa Gede Hendra
Published: August 2019

Informasi yang diperoleh oleh siswa maupun guru Sejarah SMA terkadang hanya berupa gambar ilustrasi yang tidak cukup menggambarkan bagaimana kehidupan manusia purba di Indonesia. Oleh sebab itu, peneliti memanfaatkan teknologi Virtual Reality sebagai media penyampaian informasi agar proses pembelarajan menjadi semakin menarik. Tujuan penelitian ini adalah: (1) Untuk mengembangkan Aplikasi Virtual Reality 3D Pengenalan Manusia Purba bangsa Indonesia untuk kelas X. (2) Untuk mengetahui respon siswa kelas X terhadap implementasi Aplikasi Virtual Reality 3D Pengenalan Manusia Purba bangsa Indonesia. Pengembangan aplikasi ini menggunakan model ADDIE. Subjek penelitian ini yaitu siswa kelas X SMA Negeri 2 Singaraja. Terdapat 3 (tiga) pengujian pada penelitian ini, pengujian tersebut diantaranya yaitu uji pemahaman siswa, uji respon pengguna dan uji pengalaman pengguna. Pengujian untuk mengetahui pemahaman siswa dilakukan dengan pemberian pretest dan postest dan didapatkan nilai N-Gain sebesar 0.4 yang masuk kriteria sedang. Pengujian untuk mengetahui respon siswa setelah menggunakan aplikasi ini dilakukan dengan metode angket dan memiliki hasil dengan persentase rata-rata sebesar 82,3% yang artinya aplikasi masuk kategori sangat baik. Selain itu juga dilakukan pengujian pengalaman pengguna. Pengujian ini dilakukan dengan menggunakan User Experience Quistionneir (UEQ) dengan hasil daya tarik dan stimulasi memiliki nilai excellent sedangkan kejelasan, efisiensi, ketepatan dan kebaruan memiliki nilai good.
FILM DOKUMENTER SENI LUKIS WAYANG KAMASAN KLUNGKUNG BALI
Authors: Pranata I Kadek Evry , Sindu I Gede Partha , Putrama I Made
Published: August 2019

Penelitian ini bertujuan untuk (1) menghasilkan rancangan dan mengimplementasikan hasil rancangan pengembangan Film Dokumenter Seni Lukis Wayang Kamasan. (2) mengetahui respon masyarakat Bali khususnya masyarakat  Desa Kamasan terhadap hasil akhir Film Dokumenter Seni Lukis Wayang Kamasan. Jenis penelitian yang digunakan dalam penelitian ini adalah penelitian dan pengembangan dengan model cyclic strategy. Film dokumenter ini diimplementasikan dengan menggunakan aplikasi Adobe Premiere Pro CC 2018 dalam proses video editing, Adobe After Effects CC 2018 untuk pembuatan video animasi, Adobe Audition CC 2018 dalam proses sound editing, serta Adobe Photoshop CC 2018 untuk pembuatan desain keperluan film dokumenter.Hasil penelitian menunjukkan bahwa Film Dokumenter Seni Lukis Wayang Kamasan Klungkung Bali berdasarkan uji ahli isi, dan uji ahli film dokumenter memperoleh rata-rata persentase yaitu 97.16% dengan tingkat pencapaian “Sangat Baik”. Uji respon penonton untuk film dokumenter ini rata-rata persentase yaitu 91.18% dengan tingkat pencapaian “Baik”. Kesimpulan yang didapatkan yaitu Film Dokumenter Seni Lukis Wayang Kamasan Klungkung Bali sudah sangat baik dan bisa digunakan sebagai media informasi sejarah seni lukis wayang kamasan.
GOD TEMPLE (GEOGRAPHIC OF DEWATA TEMPLE): APLIKASI PERSEBARAN PURA PADA PERANGKAT MOBILE APPLICATION BERBASIS CROWDSOURCHING
Authors: Widiantika Made , Resika I Ketut , Saindra Santyadiputra Gede
Published: August 2019

Semua masyarakat baik yang berwisata maupun yang melakukan ibadah tentunya harus mengetahui semua tempat-tempat ini. Beberapa permasalahan utama yang dialami adalah mengetahui status pura, dan letak dari pura. Maka dari itu diperlukan adanya strategi yang dapat memberikan informasi yang dibutuhkan, sekaligus memaparkan berbagai macam-macam pura berdasarkan fungsi dan keunikan masingmasing.Metode yang digunakan untuk mengidentifikasi masalah dan pengumpulan data melalui angket serta data sebelumnya yang telah ter arsipkan berupa file. Selanjutnya, menganalisis persyaratan sistem, perangkat lunak yang digunakan dalam membangun aplikasi ini adalah Java sebagai bahasa pemograman, MySQL sebagai database server. Hasil dari penelitian ini adalah Sistem Informasi Geografis Persebaran Pura pada perangkat Mobile Berbasis Crowdsourching. Dalam aplikasi ini menunjukkan lokasi dimana keberadan pura , keterangan pura, tanggal piodalan pura dan foto bangunan pura. Hasil pengujian menunjukkan aplikasi telah memenuhi standar ISO 25010 pada aspek respon pengguna yaitu menggunakan usability testing UEQ (user experience questionnaire) dengan rata-rata pada aspek daya tarik 2.32, kejelasan 2.43, efisiensi 2.25, ketetapan 2.33, stimulasi 2.28 dan kebaruan 2.03,pada aspek kelayakan aplikasi menggunakan functional suitability 100%, compatibility aplikasi kompatibel 100% dari sisi co-existence, dan berbagai tipe perangkat, dan pengujian performan efficiency aplikasi berhasil dijalandan di berbagi tipe perangkat tanpa terjadi memory leak, dengan rata-rata nilai pada time behavior slow UI thread 20%, CPU Utilization rata-rata 32%,dan Memory Utilization rata-rata sebesar 90Mb.
PENGEMBANGAN GAME EDUKASI MOBILE MAKHLUK HIDUP KELAS REPTILIA UNTUK SISWA SMP
Authors: Rizalni Risya Listya , Trisnadoli Anggy , Zul Muhammad Ihsan
Published: August 2019

Kelas reptilia merupakan bagian dari materi klasifikasi makhluk hidup yang terdapat pada mata pelajaran Biologi untuk siswa-siswi SMP kelas VII. Dalam proses belajar mengajar, media pembelajaran merupakan salah satu unsur terpenting selain metode pembelajaran. Manfaat media pembelajaran adalah melancarkan interaksi antara guru dengan siswa sehingga kegiatan pembelajaran akan lebih efektif dan efisien. Penyampaian materi pelajaran ini masih menggunakan sistem tradisional, sehingga kreativitas siswa kurang berkembang. Selain itu, untuk memahami ciri-ciri hewan kelas reptilia hanya dilihat dari gambar yang ada pada buku pelajaran. dan siswa sering mendapatkan nilai buruk bahkan harus melakukan remedial pada materi pelajaran tersebut. Oleh karena itu, dibangun sebuah game edukasi dengan tampilan model hewan 3D untuk pembelajaran materi klasifikasi makhluk hidup kelas reptilia. Berdasarkan pengujian manfaat belajar yang telah dilakukan ke siswa SMP kelas VII, didapatkan bahwa siswa yang menggunakan aplikasi game mengalami peningkatan pemahaman sebesar 40.5%.  Pada pengujian fungsional, didapatkan bahwa fungsi pada aplikasi dapat berjalan sesuai dengan hasil yang diharapkan. Serta berdasarkan pengujian umpan balik pengguna dapat disimpulkan bahwa game edukasi ini dapat membantu siswa dalam memahami materi perbedaan makhluk hidup berdasarkan ciri-ciri makhluk hidup kelas reptilia.
ANALISIS DAN IMPLEMENTASI ALGORITMA GENETIKA PADA PENJADWALAN MATA PELAJARAN DI MADRASAH TSANAWIYAH MIFTAHUL ‘ULUM DENPASAR
Authors: Iswara Ida Bagus Ary Indra , Saputra Dio Restu
Published: August 2019

Subject scheduling is an important element in teaching and learning activities in schools. Scheduling lessons often take a long time due to many factors such as determining teacher teaching hours allocation, the limited number of teachers and teaching in a large number of classes. The problem that often arises is the clash of teaching hours at the same time. One solution to scheduling problems is through the optimization method of Genetic Algorithms. Genetic Algorithms are methods inspired by Mendell's theory of genetics and evolution to solve problems that require optimization. The constraints that were used as constraints in this study were clashing hours of teaching teachers and clashing the same class at the same time. In this study, the results of implementing Genetic Algorithms as a method of optimizing lesson scheduling have not yet obtained optimal results. The solution with the best fitness value is achieved by the number of chromosomes as many as 20, the number of generations is 200, the probability of crossover (Pc) 0.5 and the probability value of mutation (Pm) is from 0.15 to 0.35. The fastest time for Pm value is 0.15 for 91.22 seconds, while for Pm value of 0.35, it takes 91.65 seconds.
FITUR EYE PROTECTION PADA LAYAR SMARTPHONE DAPAT MENGURANGI KELELAHAN MATA DAN MEMPERPANJANG DURASI PENGGUNAANNYA PADA SISWA SMP NEGERI 1 SERIRIT
Authors: Citrawathi Desak Made , Udiantari I. A. I. , Warpala S. W.
Published: August 2019

Penelitian ini bertujuan untuk mengetahui: (1) fitur eye protection pada layar smartphone dapat mengurangi kelelahan mata; dan (2) fitur eye protection pada layar smartphone dapat meningkatkan durasi penggunaan smartphone. Jenis Penelitian ini adalah penelitian eksperimental semu(quasi experimental) dengan rancangan randomize pre and post test design. Lokasi penelitian di SMP Negeri 1 Seririt Kecamatan Seririt, Kabupaten Buleleng-Bali. Pengambilan sampel dilakukan secara acak dan diambil sebanyak 26siswa. Analisis data dilakukan dengan menggunakan uji t paired dengan taraf signifikansi 5 %. Hasil penelitian ini menunjukkan bahwa ada perbedaan bermakna pada kelelahan mata sebesar 67,81 % (p < 0,05) dan durasi penggunaan smartphone sebesar 56,30 %Â  (p < 0,05) antara layar smartphone yang tidak menggunakan fitur eye protection dan yang menggunakan fitur eye protection. Disimpulkan bahwa penggunaan fitur eye protectionpada layar smartphone dapat menurunkan kelelahan mata dan meningkatkan durasi penggunaan. Disarankan agar para pengguna perangkat digital selalu memperhatikan kesehatan dan keselamatan kerja, salah satunya dengan cara mengaktifkan fitur eye protection pada layar smartphone untuk menghindari terjadinya kelelahan mata dan juga dapat memperpanjang durasi penggunaannya.
Pengaruh Pemberian Whey Protein Terhadap Pengurangan Gejala Kerusakan Otot Setelah Aktivitas Eksentrik
Authors: Sari Reno Siska
Published: August 2019

Aktivitas eksentrik adalah salah satu jenis aktivitas resistance yang sering menimbulkan kerusakan otot, yang dimulai dari 24 jam setelah aktivitas dan mencapai puncaknya pada 48 jam setelah aktivitas. Kerusakan otot menyebabkan hilangnya kekuatan otot, menurunkan range of motion sendi, meningkatkan inflamasi dan konsentrasi protein miofibril dalam darah. Rangsangan sintesis protein dan meminimalisasi muscle protein breakdown (proteolisis) adalah dua proses seluler yang penting untuk pemulihan setelah kerusakan otot. Tujuan dari penelitian ini adalah untuk membuktikan pengaruh suplementasi whey protein terhadap pengurangan gejala kerusakan otot setelah aktivitas eksentrik. Subjek penelitian ini adalah mahasiswa PJKR IKIP Budi Utomo yang dibagi secara acak ke dalam dua kelompok, 22 orang coba kelompok kontrol dan 22 orang coba kelompok perlakuan. Desain penelitian ini adalah randomized group pretest and posttest design. Aktivitas eksentrik yang dilakukan adalah aktivitas Drop Jumps pada bangku dengan ketinggian 0.5 meter. Whey protein diberikan setelah aktivitas eksentrik sebanyak 20 gram/subjek. Dalam penelitian ini whey protein diberikan dalam bentuk serbuk yang dilarutkan dengan 240 ml air mineral. Waktu pemberian whey protein dilakukan segera setelah aktivitas eksentrik, 24 dan 48 jam setelah aktivitas eksentrik (selama 3 hari pemulihan). Pengukuran kekuatan otot tungkai menggunakan back and leg dynamometer sedangkan pengukuran ROM sendi menggunakan alat goniometer. Dari hasil penelitian diketahui bahwa pemberian asupan whey protein pada kelompok perlakuan setelah aktivitas eksentrik dapat meningkatkan kekuatan otot tungkai pada 48 jam (72,3±16,1kg) dengan nilai p=0,003 (p<0,05) dan pada 72 jam (80,3±17,2) dengan nilai p=0,00 (p<0,05). Pemberian asupan whey protein pada kelompok perlakuan setelah aktivitas eksentrik juga dapat meningkatkan ROM sendi lutut pada 72 jam (130,8±3,1) whey protein sebesar 20 gram /hari setelah aktivitas eksentrik dapat meningkatkan kekuatan otot tungkai lutut pada jam ke 48 dan 72 serta ROM sendi pada jam ke 72
Pemanfaatan Drone DJI Phantom 4 Untuk Identifikasi Batas Administrasi Wilayah
Authors: Suciani Ayu , Rahmadi M Taufik
Published: August 2019

Pemanfaatan UAV (Unmanned Aerial Vehicle) atau drone hingga saat ini telah banyak digunakan antara lain untuk monitoring tata ruang kota, identifikasi perubahan lingkungan, konstruksi bangunan, industri, pemetaan perikanan, lahan, kehutanan, tata ruang, hingga pemetaan batas wilayah administrasi. Batas wilayah administrasi merupakan batas atau garis khayal yang hanya terdapat pada peta dan tidak ada di lapangan sesuai dengan ketentuan hukum yang berlaku. Penelitian ini bertujuan untuk menguji tingkat ketelitian hasil foto drone untuk batas administrasi wilayah. Penelitian ini menggunakan metode interpretasi manual. Penelitian ini dilakukan di sebagian wilayah administratif Kota Langsa, yaitu Kelurahan Sidodadi, Kelurahan Serambi, dan Kelurahan Mulia. Pemilihan wilayah kajian ini disebabkan oleh beberapa faktor seperti kepadatan permukiman, pertumbuhan pembangunan yang cepat, dan tingkat kepadatan penduduk yang tinggi. Foto udara perekaman drone pada penelitian ini memiliki resolusi spasial 0.5 meter, sehingga memberikan kenampakan objek yang jelas dan detail.Kata Kunci: Pemetaan, Administrasi, Drone DJI Phantom 4Utilization of UAV (Unmanned Aerial Vehicle) or drone has been widely used in urban spatial monitoring, identification of environmental changes, building construction, industry, fishery mapping, land, forestry, spatial planning, and mapping administrative boundaries. The administrative boundary  is an imaginary line that only available in the map but not exactly exist on earth based on applicable law. The aim of this study is to examine the accuracy of the photo result of the DJI Phantom 4 for regional administrative boundaries. This study uses manual interpretation methods. This research was conducted in some villages of Langsa City, they are; Sidodadi, Serambi, and Mulia. The region selection is based on several factors such as settlement density, rapid development growth, and high population. The aerial photos of drone recording in this study has a spatial resolution 0.5 meters, so that give the clear appearance and detailed object.Keyword: Mapping, Administration, Drone DJI Phantom 4
Keterjangkauan Fasilitas Publik di Kawasan Pulau-Pulau Kecil : Studi Kasus Kabupaten Administrasi Kepulauan Seribu
Authors: Wibisono Hafidz , Musthofa Azis , Haryanto Indrawan
Published: August 2019

Ukuran daratan yang kecil, populasi yang sedikit, sumber daya terbatas, dan isolasi geografis merupakan karakteristik khusus yang menjadikan kawasan pulau-pulau kecil objek yang menarik untuk diteliti. Dalam konteks penyediaan fasilitas publik, bukan hanya ketersediaan fasilitas yang menjadi fokus perhatian, namun keterjangkauan fasilitas dari kawasan permukiman yang tersebar di berbagai pulau menjadi hal yang penting untuk dipertimbangkan. Terbatasnya jaringan transportasi, serta moda transportasi publik merupakan beberapa keterbatasan yang harus diatasi dalam menyediakan pelayanan publik di kawasan pulau-pulau kecil. Dengan menggunakan studi kasus di Kabupaten Administrasi Kepulauan Seribu, penelitian ini memberikan gambaran secara empiris terkait dengan isu ketersediaan dan keterjangkauan  fasilitas publik di kawasan pulau-pulau kecil. Adapun penelitian ini menemukan bahwa masyarakat di beberapa pulau berpenghuni masih membutuhkan waktu tempuh yang cukup lama untuk mengakses layanan beberapa fasilitas public.Kata kunci: pulau kecil, keterjangkauan, ketersediaan, fasilitasLimited land size and resources, small population, and geographically isolated are particular characteristics that make small islands an interesting research object. In the context of facilities provision, the accessibility of the facilities from residential areas which spread across several island is as important as the facilities availability. Lack of network between islands, limited publik transportation are some of constraints that have to overcome in providing equitable facilities. By using a case study in Administration Regency of Kepulauan Seribu, this research provides an empirical description related to the availability and accessibility of public facilities in small islands. Furthermore, this research found that several public facilities are still difficult to be accessed by communities in certain islands.Key words: small islands, accessibility, availability, facilities
Zonasi Pemanfaatan Lahan Pasca Penambangan Pasir di pesisir Cipatujah, Kabupaten Tasikmalaya, Jawa Barat
Authors: As'ari Ruli , Mulyanie Erni , Rohmat Dede
Published: August 2019

Aktivitas tambang pasir besi di Pantai Cipatujah Kabupaten Tasikmalaya memberikan dampak negatif bagi lingkungan. Beberapa permasalahan pasca penambangan pasir besi yaitu; rusaknya ekosistem, kondisi lahan yang rusak, pemukiman penduduk terganggu polusi, rusaknya prasarana transportasi dan terjadi konflik di masyarakat. Kondisi pantai pasca penambangan pasir besi saat ini sudah mengalami perubahan, beberapa kawasan telah di manfaatkan untuk budidaya udang vannamei. Diperlukan zonifikasi kawasan pemanfaatan lahan pantai pasca penambangan pasir besi untuk meminimalisir dampak negatif yang timbul akibat aktivitas penambangan pasir besi. Metode penelitian ini adalah Deskriptif Survey, teknik pengumpulan data melaui survey lapangan, wawancara, studi dokumentasi dan studi literatur. Analisis data dilakukan melalui Pemetaan Kawasan Pantai Cipatujah dengan mengklasifikasikan kawasan menjadi tiga zona utama berdasarkan karakteristik aktivitas masayarakat dan potensi setiap kawasan pantai pasca penambangan pasir besi. Lokasi Penelitian di Kawasan Pantai Selatan yang berada di Kecamatan Cipatujah Kabupaten Tasikmalaya. Hasil Penelitian menunjukkan zonasi kawasan reklamasi lahan pasca penambangan pair besi di Kecamatan Cipatujah dibagi menjadi 3 Zona diantaranya: Zona I: merupakann zona kawasan budidaya udang vannamei, Zona II: Zona Kawasan Pariwisata, Zona III: zona kawasan konservasi.Kata Kunci: Zonasi, Reklamasi lahan, Pasir BesiIron sand mining activities at Cipatujah Beach Tasikmalaya District have a negative impact on the environment. Some problems post iron sand mining are; damage to the ecosystem, damaged land conditions, pollution of the population, damage to transportation infrastructure and conflict in the community. The condition of the coast after iron sand mining has changed, some areas have been utilized for Vannamei shrimp cultivation. Zonification of coastal land use areas is needed after iron sand mining to minimise the negative impacts arising from iron sand mining activities. The method used in this study is a descriptive survey method with data collection techniques used in field surveys, interviews, documentation studies and literature studies. Data analysis was carried out through Mapping the Cipatujah Coast Area by classifying the area into three main zones based on the characteristics of community activities and the potential of each coastal area after iron sand mining. Research Sites on the South Coast in the Cipatujah District of Tasikmalaya Regency. The results showed zoning of the land reclamation area after iron pair mining in Cipatujah subdistrict was divided into 3 zones including Zone I: zone of Vannamei shrimp cultivation area, Zone II: Tourism Zone, and Zone III: zone of ecological conservation.Keywords: Zoning, land reclamation, Sand, Mining, Coastal
Analisis Ketelitian Titik Kontrol Dalam Rangka Pemetaan Topografi Skala Besar di Lahan Field Research Center (FRC) Sekolah Vokasi Universitas Gadjah Mada
Authors: Prasidya Anindya Sricandra , Rahardjo Untung
Published: August 2019

Peta topografi diperlukan dalam membantu perencanaan detail suatu area. Field Research Center (FRC) adalah lokasi kampus baru dari Sekolah Vokasi, UGM (FRC SV-UGM) di Wates, Kulon Progo yang belum memiliki peta topografi skala besar. Dalam rangka untuk menyediakannya,  titik kontrol dan kerangka dasar harus disediakan dahulu. Penelitian ini bertujuan menganalisis ketelitian titik kontrol yang akan dipakai untuk menghasilkan peta topografi skala besar dari FRC SV-UGM. Pelaksanaannya terdiri atas beberapa tahapan, dimulai dari pemasangan, pengukuran, pengolahan, dan menganalisis titik kontrol, penyediaan titik kerangka dasar dalam bentuk poligon tertutup, pengukuran dan pengolahan datanya, pengukuran detil situasi (X, Y, Z), menyajikannya dalam bentuk peta dan menguji akurasinya, dan mengevaluasi hasil. Hasil yang diperoleh adalah koordinat geodetik dari tiga titik kontrol (BM1, BM2, FRC4) hasil dari pengukuran GNSS moda jaringan. Ketelitian horizontalnya kurang dari 9,1 mm dan ketelitian vertikalnya kurang dari 20,4 mm. Mengacu pada Standar Nasional Indonesia Jaring Kontrol Horizontal (SNI JKH), hasil ini telah memenuhi standar ketelitian orde-3. Selain itu, 8 titik kerangka dasar poligon tertutup telah memenuhi standar, kesalahan penutup sudutnya adalah 28,25, rasio ketelitian linier poligon adalah 1:13.601, dan kesalahan penutup beda-tinggi adalah 7,9 mm. Hasil ini memenuhi standar ketelitian orde-4 pada SNI JKH dan kelas LC pada SNI JKV. Hasil akhir berupa peta topografi skala 1:1.000 yang berisi semua detil planimetrik dan ketinggiannya. Pengujian akurasi peta ini didasarkan pada Peraturan Kepala Badan Informasi Geospasial (Perka BIG) No 15/2014. Komponen horizontal peta ini memenuhi standar ketelitian kelas 3 peta topografi skala 1:1.000 dengan CE90 < 0,5, sedangkan komponen vertikalnya memenuhi standar kelas 1 dengan LE90 < 0,2. Sehingga, dapat disimpulkan bahwa titik kontrol hasil pengukuran dengan pengamatan GNSS yang memenuhi orde-3 SNI JKH seperti pada penelitian ini dapat menghasilkan ketelitian komponen horizontal kelas 3 dan vertikal kelas 1 dari peta topografi skala 1:1.000.