bluuebunny/crossref_metadata_2025 huggingface dataset:
The specifics of speech development of preschoolers with different forms of cerebral palsy
Authors:   «Samara State Social and Pedagogical University, Fedosova Oksana Y. , Gordievsky Anton Y. ,   Samara State Socio-Pedagogical University
Published: March 2022

Speech therapy disorders against the background of general motor dysfunction of children with cerebral palsy dramatically reduce their communicative abilities, significantly limiting the possibility of socialization in modern society. In a comprehensive study conducted with the participation of children with cerebral palsy aged six to seven years, the presence of a relationship between the pathological state of the nervous system and the specifics of motor and speech disorders was established. Taking into account the combined symptoms of cerebral palsy in the course of pedagogical work provides early prediction of speech disorders, primarily of a dysarthric nature, and provides an opportunity for a full-fledged choice of the main directions and specific techniques of speech therapy.
Model of socialization of students with intellectual disabilities in individual education
Authors:   Yaroslavl state pedagogical university named after К. D. Ushinsky, Kiseleva Tatyana G. , Kuznetsova Natalya A. ,   Yaroslavl state pedagogical university named after К. D. Ushinsky
Published: March 2022

The article reveals the mechanism of socialization and social adaptation of students with intellectual disabilities through the inclusion of normotypical peers in the environment, since inclusive education is considered as one of the conditions for the implementation of GEF education of children with intellectual disabilities. Children with severe disabilities who study at home require special attention. For the socialization of such children, the authors developed and theoretically substantiated a model for the inclusion of schoolchildren with disabilities in individual education in the environment of normotypical peers. This model is represented by three clusters that describe goals, objectives, approaches, principles, forms, conditions of implementation, as well as criteria and methods for evaluating results.
Analysis of the results of the study of the formation of communicative skills in impudent preschoolers
Authors:   Yaroslavl state pedagogical university named after К. D. Ushinsky, Tikhomirova Larisa F. , Khanova Evgeniya S. ,   Yaroslavl state pedagogical university named after К. D. Ushinsky
Published: March 2022

This article is devoted to the actual problem of the formation of communication skills in visually impaired children of middle preschool age in an inclusive group. The article describes a diagnostic study of the formation of communication skills in children of middle preschool age with visual impairment in comparison with normally developing children. The authors analyze the results of diagnostics, give a qualitative and quantitative assessment of the results, prove significant differences in the formation of communication skills in children with visual impairment and normally developing peers.
Peculiarities of communication skills formation in preschoolers with delayed mental development
Authors:   Yaroslavl state pedagogical university named after К. D. Ushinsky, Kiseleva Tatyana G. , Mataulina Aleksandra E. ,   Yaroslavl state pedagogical university named after К. D. Ushinsky
Published: March 2022

The article presents the results of a comparative study of communication features in children with delayed mental development and normotypical children. The research methodology is based on the approach of G.M. Andreeva, who distinguished three components in the structure of communication: perception, communication and interaction. Comparison with normotypic peers allowed the authors to highlight the necessary pedagogical conditions for the organization of an inclusive educational space, which ensure the formation of communicative competence of preschoolers with developmental disabilities. To conduct the study, the authors chose diagnostic techniques equally applicable in working with both normotypic children and children with developmental disabilities.
Features of self-esteem in primary school children with mental retardation in an integrated classroom
Authors:   Yaroslavl state pedagogical university named after К. D. Ushinsky, Tikhomirova Larisa F. , Bubnova Yana A. ,   Yaroslavl state pedagogical university named after К. D. Ushinsky
Published: March 2022

This article is devoted to the problem of self-esteem of primary school children with mental retardation. The authors of the article reveal the relevance of this topic, define the purpose and objectives, as well as the object and subject of the study of self-esteem of this category of children in the conditions of integrated learning. Diagnostic methods are selected, and quantitative and qualitative data obtained as a result of diagnostics on the features of self-assessment of younger schoolchildren with ZPR in conditions of integrated learning are analyzed.
The specifics of the correctional speech therapy process in a distance format
Authors:   Yaroslavl state pedagogical university named after К. D. Ushinsky, Grosenkova Victoria A. , Paltusova Ekaterina M. ,   Yaroslavl state pedagogical university named after К. D. Ushinsky
Published: March 2022

Distance learning opens up wide opportunities for corrective work with children of preschool and primary school age with speech disorders. The article discusses the issues of changing the modern education system, gives the concept of distance learning, describes the advantages of information and computer technologies; highlights speech therapy technologies that are used in distance learning. The authors reveal the content of the forms of teaching the correctional speech therapy process in a distance format.
Formation of functional literacy in the sphere of healthy lifestyle of students with peculiarities of psychophysical development
Authors:   National Institute of education of the Republic of Belarus, Valkovich Olga F.
Published: March 2022

The article clarified the concept «functional literacy in the sphere of healthy lifestyle», concretized the methodological foundations for the formation of functional literacy of students with peculiarities of psychophysical development, characterised functional literacy in the sphere of healthy lifestyle, revealed the features of the formation of functional literacy of students with peculiarities developmental disabilities, presented possible types of work on the formation of functional literacy by means of academic subjects.
The specifics of the organization of speech therapy assistance to primary schoolchildren with speech disorders during distance learning
Authors:   Nizhny Novgorod Institute for the development of education, Tsilina Ekaterina A.
Published: March 2022

The article is devoted to the analysis of the difficulties encountered by the speech therapy service workers in the organization of remote education for primary schoolchildren with speech disorders. The technical, organizational, methodological difficulties from the position of the teacher and other participants in educational relations are considered. The reasons for the problems arising at different stages of speech therapy classes are described and explained. The advantages of using a remote method of communication with students in the process of correcting their speech activity are evaluated.
Training of personnel in the field of inclusive education through the organization of a resource center
Authors:   Auxiliary school № 24 in Orsha, Republic of Belarus, Semenkova Elena A.
Published: March 2022

This article examines the problem of training personnel in the field of inclusive education for children with developmental disabilities, ensuring the readiness of teachers to work in conditions of inclusion. The practical experience of the formation of professional competencies of teachers through the organization of the activities of the resource center on inclusive education is presented. The qualitative and quantitative characteristics of the preparedness of the teaching staff to work with children with specific features of psychophysical development are presented.
In-house training as a condition for the training of teaching staff in educational institutions
Authors:   Center for helping children, Yaroslavl, Russia, Bayun Olga K. , Ivanova Evgeniya A. ,   Center for helping children, Yaroslavl, Russia
Published: March 2022

The authors of the article draw attention to the fact that the policy of modernization and standardization of the educational system involves the creation of favorable conditions for improving the quality of education, in accordance with modern requirements; the renewal of education as a whole is accompanied by the introduction of various innovations in individual educational organizations. The authors identify a number of competencies that determine the successful socialization of the younger generation in society.
Experience in organizing practice-oriented classes with students of Omsk State Pedagogical University in the context of the COVID-19 pandemic
Authors:   Omsk state pedagogical university, Artemeva Valeriya D. , Myachina Elena K. ,   Omsk state pedagogical university
Published: March 2022

The article reveals the issues of organizing and conducting practiceoriented classes by students of higher educational institutions in the online process with schoolchildren with speech pathology. The experience of technical and psychological-pedagogical support of schoolchildren with speech pathology during distance learning in the framework of the subject course "Mathematics" is presented. The author gives an example of the organization of practice-oriented training of students during the COVID-19 pandemic, which took place on the basis of the Omsk State Pedagogical University during the pandemic.
Determination of the readiness of teachers to work with children with disabilities as a condition for inclusive practice
Authors:   Yaroslavl state pedagogical university named after К. D. Ushinsky, Shmeleva Olga A. , Shabalina Svetlana A. ,   Yaroslavl State Pedagogical University named after K.D. Ushinsky
Published: March 2022

The article examines the problem of the readiness of teachers to implement inclusive education of children with disabilities in the conditions of combined groups of a preschool educational organization of general developmental type. The parameters of the professional and psychological readiness of a teacher to include a pupil with special educational needs in the educational process are presented, as well as the analysis and interpretation of the results of the study.
In-person forms of developing professional competence among speech pathologists
Authors:   Belarusian State Pedagogical University named after Maxim Tank, Sosnovskaya Alla V.
Published: March 2022

The following article provides comprehensive coverage of the issue of developing professional competence among speech pathologists. Author presents thorough analysis of relevant theories, as well as stages of conducting in-person and interactive training of fellow professionals. The publication also gives detailed content of the aforementioned forms of improving professional competence of special education teachers. Additionally, the author substantiates the relevance of the issue of improving professional competence of special education teachers through in-person forms of professional training.
Features of drawing up an advanced training program on inclusive education for children with disabilities
Authors:   Correctional kindergarten with inclusion, Nur-Sultan, Republic of Kazakhstan, Shaymardanova Zhannel M.
Published: March 2022

The article highlights one of the topical areas in education, the professional readiness of teaching staff in the Republic of Kzakhstan. The article presents the results of a study involving state pedagogical staff of the Department of Education to identify professional difficulties in organizing inclusive education in preschool educational institutions and in schools. On the basis of the law on inclusive education in the Republic of Kazakhstan and the principles of inclusion, a program for advanced training of teachers, parents and all interested persons on the organization of inclusive education and accompanying children with disabilities in general education schools and in preschool educational institutions has been presented.
Implementation of the continuity of speech therapy work in preschool and primary education
Authors:   Yaroslavl state pedagogical university named after К. D. Ushinsky, Grosenkova Victoria A. , Averyanova Tatyana A. ,   Yaroslavl state pedagogical university named after К. D. Ushinsky
Published: March 2022

The article proves the need to provide speech therapy assistance to senior preschool children who receive educational services in a rural kindergarten. This area of work is relevant especially for children preparing to become first graders. We consider it necessary to build a system of speech therapy work within the framework of the implementation of the continuity of preschool and primary education. The author cites diagnostic data for children of the preparatory group for school, pointing out the obvious difficulties in their mastering of speech.
The use of information and communication technologies in the development of sensorimotor skills in preschool children with speech disorders
Authors:   Vladimir State University named after A.G. and N.G. Stoletov, Usenkova Ekaterina V. , Shirokova Olga A. ,   Vladimir state university named after A. G and N. G. Stoletovs
Published: March 2022

The dissemination of information and communication technologies in speech therapy practice makes it possible to open up new training options, which makes it possible to achieve better results in correctional work in order to eliminate violations of speech and sensory development of children. Children develop a holistic view of the world around them, social and cultural life, and their own personality. The formation of knowledge concerning a variety of areas is carried out, the ability to make decisions in accordance with their own knowledge and experience is improved, skills of interaction with other people of different ages are created. The article offers various options for the use of information and communication technologies in the formation of sensorimotor skills in children with speech disorders.
The development of figurative memory in older preschool children with mental retardation through computer technology
Authors:   Tula State Pedagogical University named after L.N. Tolstoy, Vasina Yuliya M.
Published: March 2022

The article discusses the use of computer technologies in the development of figurative memory in older preschool children with mental retardation. The features of memory development in children with developmental disorders are revealed. Criteria and diagnostic tools for identifying the level of development of figurative memory in children with this disorder are described. A series of computer training programs aimed at developing the basic properties of figurative memory are analyzed.
An integrated approach to the correction of dyslexia in primary schoolchildren with mental retardation
Authors:   Yaroslavl State Pedagogical University named after K.D. Ushinsky, Shabalina Svetlana A. , Dyachkova Alena S. ,   Yaroslavl state pedagogical university named after К. D. Ushinsky
Published: March 2022

The article discusses the problem of improving the effectiveness of correctional work to eliminate dyslexia in children of primary school age with mental retardation. The methods of diagnostics, the main directions and content of correctional work are described, the need to involve in this process not only a speech therapist, teachers of the Russian language and literature, but also teachers of additional education is substantiated. Some methods of work on the correction of dyslexia in younger schoolchildren with mental retardation are given. In the article outlines the prospects for correctional work in this direction.
The Relationship Between EFL Teachers’ Professional Identity and Professional Autonomy
Authors: Dilek Ekru , Altas Betul
Published: March 2022

This study aims to identify 250 Turkish EFL teachers’ level of professional identity and professional autonomy. This study also aims to investigate whether the results differ by gender, the school in which they work, education level and work experience. Furthermore, the study aims to identify whether there is a significant relationship between EFL teachers’ professional identity and their professional autonomy. In this survey-based research, the results demonstrate that EFL teachers have a very high level of professional identity and a high level of professional autonomy, and the results differ by EFL teachers’ gender, school type and work experience. Results also reveal that there was a significant, positive and moderate relationship between professional identity and professional autonomy of EFL teachers. This study suggests that the freer EFL teachers feel to make decisions in their teaching and profession, the more they can define their identity in the teaching profession.
Dysvascular Transtibial Amputation Due To Artery Stenosis: A Case Report Study
Authors: Imanawanto Kurnia , Utami Ditaruni Asrina
Published: March 2022

Below-knee (BK) amputation is one of the most commonly performed actions in dysvascular cases, but rare caused by arterial stenosis. Those had significant impacts on clinical functions and affect the contralateral limb, so its need adequate supervision during rehabilitation programs. The report are to describe the stump wound healing of the patient after amputation surgery, stump preparation at pre-prosthetic phase, prevention of knee contracture, prosthetic preparation and use, gait training and evaluation of unaffected limb. A 44-years old female with right below-knee amputation caused by stenosis of right peroneal and dorsalis pedis artery, and the wound in the residual limb was not healed within 4 weeks. She got rehabilitation to accelerate stump healing and stump shaping, maintain knee flexibility, muscle strengthening, cardiovascular endurance, transfer and ambulation. She had good compliance to the programs and achieved independent ambulation using the prosthetic within 6 months. Improvement in residual limb healing within 6 weeks, pain reduction from VAS score 3 to zero, and stump shape changes from buldging to conical. And also in knee joint range of motion, transfer ability, gait pattern using BK prosthetic (by modifying shoe components), and the patient's ability to carry out ADL (BI score 75 to 100). Laser therapy, stump shaping, flexibility exercise, strengthening exercise, endurance exercise, ambulation exercise and prosthetic use on transtibial dysvascular amputation showed good results for ADL. Careful examination to the unaffected limb could identify early occurence of stenosis. Early intervention could prevent future ischaemia and amputation.
Non-Pharmacological Balance Therapy on Diabetic Peripheral Neuropathy Patients with Balance Disorders
Authors: Sibarani Jeremy Nicolas , Wigati Kristanti Wanito , Subadi Imam
Published: March 2022

ABSTRACTBackground: Patients with diabetic peripheral neuropathy (DPN) suffers from propioceptive ability and mobility disturbance which can potentially affects balance. There are various balance therapy options for DPN patients. The purpose of this study was to determine the effectiveness of various non-pharmacological therapies (surgery, traditional medicine, exercise and assistive devices) in DPN patients with balance disorders.Aim(s): To determine the effectiveness of non-pharmacological balance therapy in people with diabetic peripheral neuropathyMaterial and methods: A systematic review was conducted using randomized controlled trial study articles found using PICO characteristics in ScienceDirect and PubMed in the last 10 years. All articles were selected based on PRISMA and descriptive analysis was carried out on the selected articles.Result: Significant balance improvement found in traditional Thai massage, physical exercise therapy, assistive device therapy with whole-body vibration, and assistive device therapy with electrical stimulation. Surgical therapy with unilateral nerve decompression did not provide a significant measurable balance improvement.Conclusions: Physical exercise therapy, traditional Thai foot massage, WBV and electrical stimulation therapy (with the exception of TENS on the knee) significantly improve balance. Meanwhile, unilateral nerve decompression surgical therapy did not improve the balance significantly.
Comprehensive Rehabilitation of Severe Tuberculous Meningitis: A Case Series
Authors: Suisan Yohan Christian , Thohari Khamim
Published: March 2022

Tuberculous Meningitis (TBM) is a severely disabling condition that often leads to death. It requires the right intensive treatment to minimize disability, speed up recovery, and reduce the risk of death. Rehabilitation is one of the key components in managing TBM. Rehabilitation is expected to speed up recovery and prevent disabilities. The purpose of this case series was to highlight the effectiveness of a comprehensive rehabilitation program in severe TBM patients at Intensive Care Unit (ICU) settings. We present two cases of severe TBM that showed significant changes after the rehabilitation program started. Both patients were at GCS 111. Rehabilitation program was a therapist-based multimodal sensory stimulation in a comprehensive ICU setting with approximately 2 weeks duration. After 5 days of rehabilitation, the first patient’s consciousness began to improve. The second patient’s consciousness began to improve after 1 week of rehabilitation. After approximately 2 weeks, both of them were already at GCS 456 and then transferred to the High Care Unit (HCU). There were only minor disabilities as they were transferred. The rehabilitation program was adapted and continued at HCU. After 1 month, both of them got discharged to home. These cases highlight the importance of rehabilitation programs to be included in the management of TBM patients.
Kripto Para Teknolojileri: Kripto Para Seçimine Etki Eden Faktörlerin AHP Yöntemi İle Değerlendirilmesi(Cryptocurrency Technologies: Evaluation of Factors Affecting Cryptocurrency Selection by AHP Method)
Authors: Boztosun Derviş , Arslan Emre , Yıldırım Ali , Karslıoğlu Birsen , Demirtaş Özgür
Published: March 2022

Amaç –Bu çalışmanın amacı; kripto para seçimine etki eden faktörlerin ortaya çıkartılması hususunda subjektif değerlendirmelerin objektif ağırlıklandırmalar yoluyla tespit edilmesidir.Yöntem -Çalışmada, Analitik Hiyerarşi Prosesi (AHP) çok ölçütlü karar vermetekniği kullanılmıştır. Kriptoloji ve kripto para alanında uzman ekipten oluşan yedi kişilik bir değerlendirme ekibi kriter ve alt kriterleri, ikili karşılaştırmalar yoluyla değerlendirmiştir. Buradan yola çıkarak, bu değerlendirmeler, Analitik Hiyerarşi Prosesi ile global ağırlık vektörlerine dönüştürülmüştür.Bulgular -Analiz sonuçlarına göre, işletmelerin kripto para yatırımı yapan bireysel portföy yöneticilerinin kripto para seçimini etkileyen kriterlerde en yüksek skora sahip olanlar “Teknolojik Merak”, “Kişinin Parası Üzerindeki Kontrol Gücü” ve “Veri ve İşlem Gizliliği” olarak belirlenmiştir. Bunun yanında, en düşük skora sahip kriterler ise “Sistem Üzerinde Kontrol Gücü”, “Coin Üreticisi” ve “Kimlik Bilgisi Gizliliği”, olarak tespit edilmiştir.Tartışma: Bu çalışmada, kripto para yatırımı yapan bireysel portföy yöneticilerinin kripto para seçimini etkileyen kriterlerin ağırlıklandırılması ve en önemli kriterin belirlenmesi amacıyla çok kriterli karar verme yöntemlerinden biri olan Analitik HiyerarşiProsesi (AHP) yöntemi ile analizler gerçekleştirilmiştir. AHP ile gerçekleştirilen analizde kripto para yatırımı yapan bireysel portföy yöneticilerinin kripto para seçimini etkileyen kriterler tespit edilmiş olup bu kriterlerin önem sıralaması yapılarak elde edilen sonuçlar tartışılmıştır.
Path Analysis of the Application of "Poisonous Tree Fruit" in the Field of Criminal Law in China
Authors: Zhang Lin
Published: March 2022

Although our country has established the exclusion rule of illegal evidence, there is no clear legislation on the evidence derived from illegal evidence. Therefore, the choice of "the fruit of the poison tree" leaves a huge space for controversy. Behind its choice not only implies the further coordination of procedural justice and substantive justice, but also becomes an important driving force to promote the modernization of China's judicial process.
A New Perspective on Four Decades of Changes in Arctic Sea Ice from Satellite Observations
Authors: Wang Xuanji , Liu Yinghui , Key Jeffrey R. , Dworak Richard
Published: March 2022

Arctic sea ice characteristics have been changing rapidly and significantly in the last few decades. Using a long-term time series of sea ice products from satellite observations - the extended AVHRR Polar Pathfinder (APP-x), trends in sea ice concentration, ice extent, ice thickness, and ice volume in the Arctic from 1982 to 2020 are investigated. Results show that the Arctic has become less ice-covered in all seasons, especially in summer and autumn. Arctic sea ice thickness has been decreasing at the rate of -3.24 cm per year, resulting in about a 52% reduction in thickness from 2.35 m in 1982 to 1.13 m in 2020. Arctic sea ice volume has been decreasing at the rate of -467.7 km3 per year, resulting in about a 63% reduction in volume, from 27590.4 km3 in 1982 to 10305.5 km3 in 2020. These trends are further examined from a new perspective, where the Arctic Ocean is classified into open water, perennial, and seasonal sea ice-covered areas based on the sea ice persistence. The loss of the perennial sea ice-covered area is the major factor in the total sea ice loss in all seasons. If the current rates of sea ice changes in extent, concentration, and thickness continue, the Arctic is expected to have ice-free summer by the early 2060s.
Moral Observer-Licensing in Cyberspace
Authors: Ran Yawei , Hou Yubo , Wang Qi
Published: March 2022

Moral observer-licensing happens when people condone others’ morally questionable conducts due to their history of moral behaviors. We investigated in four studies (N = 808) this phenomenon in the context of cyberspace and its contributing factors and boundary conditions. Study 1 determined what participants perceived as typically moral and immoral behaviors in cyberspace. Then in Study 2, participants condemned less a story character’s online immoral behavior when they were informed of the character’s prior online moral behavior than when they were not, which indicates moral observer-licensing in cyberspace. Study 3 confirmed the presence of moral observer-licensing in cyberspace and further demonstrated that a character’s prior moral or immoral behavior online respectively reduces or intensifies the negativity of the character’s subsequent immoral behavior. Finally, Study 4 showed that participants who identified with the victim in a hypothetical scenario showed less forgiveness and more condemnation of a character’s immoral behavior than those who identified with the perpetrator or the bystander. These findings are of theoretical and practical significance for our understanding of cyber ethics.
Principles and Technical Application of Mixing Zones for Wastewater Discharges to Freshwater and Marine Environments
Authors: Campos Carlos J.A. , Morrisey Donald J. , Barter Paul
Published: March 2022

A discharge mixing zone (DMZ) is a defined geographical area or volume of water in the receiving environment of a discharge where initial dilution of the effluent occurs and where exceedance of water quality criteria may be permitted. DMZs are essential to inform determination of discharge consent conditions and an important element of risk management frameworks to reduce any effects of the discharges on the environment and human health. In this review, we describe the principles and technical application of DMZs. We present an overview of the physical processes that govern the dispersion and dilution of wastewater discharges and the fate of contaminants in coastal environments and define key criteria for determining the size of DMZs. We summarize DMZ requirements in international legislation and guidance and exemplify their application to different types of discharges by means of case studies. The selected case studies illustrate different modelling tools for defining DMZs and different monitoring approaches to assess their effectiveness in achieving ecological and human health objectives.
Environmental Effects of the COVID-19 Pandemic: The Experience of Bogotá, 2020
Authors: Malagón-Rojas Jeadran , Méndez Daniela , Almentero Julia , Toloza-Pérez Yesith G. , Parra-Barrera Eliana L. , Gómez-Rendón Claudia P
Published: March 2022

During the novel coronavirus disease (COVID-19) pandemic, several environmental factors have influenced the activities and the protection policy measures. This has had a major effect on climate change and global environmental catastrophe. In many countries, the strategy of closing various activities such as tourism, industrial production, stopped normal life, transportation, among others. This closure has a positive impact on the environment. However, the massive use of masks and personal protection could significantly increase pollution worldwide. The impact on the environment needs to be calculated to have information for public health actions. In this study, we present a first overview of the potential impacts of COVID-19 on some environmental matrices in Bogota, Colombia.
The Potential of Rosuvastatin in Stabilizing Lipid Profile and Improving Clinical Outcomes in Covid-19 Patients with Coronary Heart Disease
Authors: Suciangto William , Rasyid Haerani , Nasrum Nada Indira Ramadhani , Rahmani Muhammad Zaki
Published: March 2022

Introduction : The novel coronavirus disease (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), remains a global challenge since December 2019 cause by its severe symptoms and high mortality rate. Some comorbidities are associated with clinical outcomes in COVID-19 patients, one of them is cardiovascular disease, including coronary heart disease (CHD). Statins are popularly used as the lipid controller in CHD patients. Not only controlling the lipid profile, statins also can reduce the inflammation process in COVID-19 patients. This review aims to determine the activity of statins and its potential to improve the clinical manifestation of COVID-19 patients with CHD. Methods : The method used in this paper is to examine and review the literature journal that has been published last 10 years. Results : Recent studies have shown that statins capable to control the lipid, also lowering the LDL cholesterol and increasing the HDL cholesterol. And other trials have shown that statin also have ability to reduce the inflammation and inhibit further cell damage by binding mpro, a protease produced by SARS-COV2. Conclusions:  Based on those studies, we conclude that statins have the potential effect as adjuvant therapy for clinical improvement in COVID-19 patients with CHD.
The Effectiveness Between Tamsulosin and Solifenacin Combined with Tamsulosin on Treatment of Ureteral Stent-Related Symptoms
Authors: Erida Hasbi Berry , Palinrungi Muhammad Asykar , Kholis Khoirul , Bakri Syarif , Syahrir Syakri , Kasim Firdaus
Published: March 2022

Introduction: The clinical usage of the ureteral stent caused several stent-related symptoms (SRSs), including lower urinary tract symptoms, pain, general health, work performance, sexual matter and additional problems. This study aims to evaluate the effectiveness between tamsulosin and solifenacin combined with tamsulosin for SRSs.Methods: This double blind randomized controlled trial used 50 patients. Between September 2020 and February 2021, patients underwent double-J stenting after retrograde ureteroscopy were analyzed. All patients would be randomized in a 1:1 ratio in a 1:1 ratio to receive either tamsulosin 0,4 mg (Group A: 25 participants) or tamsulosin 0,4 mg & solifenacin 5 mg combination (group B: 25 participants).We used the Ureteral Symptoms Score Questionnaire (USSQ) as an outcome measure at 1s, 2nd, 3rd and 4th weeks after stent insertion. Results: Group A was found more in women, while in group B was more in men. The highest age in group A and group B was 50-60 years old (36% and 64%). The location of stenting in group A was found more in left (60%), while the group B in the right (52%). Both groups had more patients who were normal nutritional status (60%). There was an improvement in pain and work performance after treatment in both groups, meanwhile group B showed better improvement than group A at all weeks. in addition, there was an improvement in urinary symptoms and sexual matter in group B better than in group A at 2nd to 4th week. Furthermore, group B showed better improvement in general health and additional problem only at 4th week. Conclusions: Combination therapy with tamsulosin and solifenacin improved USSQ score more than the monotherapy group. This implied that combination therapy is optimal for improving SRSs.
Intellectualization of economy and quality of human capital in the context of lifelong learning system development in the world
Authors:   Prydniprovska State Academy of Civil Engineering and Architecture, Kakhovska Olena , Rasshyvalov Dmytro ,   Taras Shevchenko National University of Kyiv, Popova Diana ,   Taras Shevchenko National University of Kyiv, Tyshchenkova Iryna ,   Dnipropetrovsk State University of Internal Affairs
Published: March 2022

In the presented research, a comprehensive analysis is undertaken in relation to such complex phenomena of the modern knowledge society as «intellectualization of economy», «human capital» and «lifelong learning» in their inextricable interrelation and within a single research discourse. Novel connotations, which have emerged within the content of these categories with the transition to the sixth techno-economic paradigm, were respectively substantiated. The definitions of intellectualization of economy have been provided with the account for specific characteristics of highly skilled labor that are formed by the system of lifelong learning. The latter, it its turn, performs social as well as economic and production functions which attests to an ambivalent nature of education as a public and simultaneously an economic good. It is proven that in all diversity of existing indices and studies on the intellectualization of economy conducted according to various indicators the assessment of the national system of lifelong learning is up until presently not used within these studies in the capacity of a significant factor of development of national human capital. The paper contains a research methodology developed and suggested by the authors for assessment of quality of human capital on the basis of analysis of the state of population enrolment in lifelong learning. The work incorporates an elaborated calculation of the corresponding index for ten countries of the world recognized as the leaders in the intellectualization of economy.
2020 guided wave inspection of California Department of Water Resources tainter gate post-tensioned trunnion anchor rods : Oroville Dam
Authors: Ray Jason , Thurmer Clayton
Published: March 2022

The Engineering and Test Branch within the Division of Operations and Maintenance of the California Department of Water Resources (DWR) and U.S. Army Corps of Engineers (USACE), Sacramento District, tasked the Sensor Integration Branch (SIB) at the Engineer Research and Develop-ment Center (ERDC) to perform non-destructive testing (NDT) on the trunnion anchor rods at Oroville Dam through the use of ultrasonic guided waves. This is the third year of this NDT. The results of the testing are presented along with qualitative analysis in determining whether a rod is in-tact or compromised. Analysis is based upon the expected results from other rods at the site, knowledge of rod response at other sites, data gathered from the trunnion rod research test bed at the ERDC, and comparison to the previous year’s effort.
THE IMPACT OF COVID-19 ON DIGITAL PAYMENT HABITS OF INDIAN HOUSEHOLDS
Authors: Saroy Rajas , Awasthy Sakshi , Singh Naveen K. , Adki Sonali M. , Dhal Sarat
Published: March 2022

The COVID-19 induced lockdown in India was an inflection point for on-boarding of new users into digital payments. Using a large survey dataset, we examine the driving factors of this shift for those who used digital payments for the first time. Apart from demographic drivers of payment choice traditionally explored in the literature, we find that this shift was significantly shaped by the degree of awareness of digital modes, access to smartphones and debit cards, and pandemic-relief welfare transfers. Users who had abandoned digital payments due to prior bad experiences switched back to such modes.
DOES BANK EFFICIENCY ENHANCE BANK PERFORMANCE? EMPIRICAL EVIDENCE FROM INDIAN BANKING
Authors: Rakshit Bijoy , Bardhan Samaresh
Published: March 2022

This paper examines the effects of cost, revenue, profit efficiency, and stability inefficiency on bank profitability in India over the period 1997 to 2017. Additionally, this study examines the effect of efficiency on profitability for banks according to their ownership and for periods with (and without) the global financial crisis. The cost, revenue, and profit efficiency scores for 70 banks in India are estimated using stochastic frontier analysis. Our key findings are as follows. First, we find that cost, revenue and profit efficiencies positively influence the profitability conditions of Indian banks. Second, banks that are inefficient adversely influence bank performance, although the global financial crisis did not seem to impact the efficiency-profitability relationship. Finally, we find that bank ownership matters for the association between its efficiency and performance.
A Prospective, Non-Randomized, Consecutive Series, Multicentre, Observational Study to Evaluate The Clinical Outcome of Ceramic-On-Ceramic Hip Resurfacing Arthroplasty Using The Ceramic, Non-Porous, Non-Cemented H1 Hip Resurfacing Arthroplasty
Authors: Al-Laith Mariam , Clarke Susannah , Halewood Camilla , Wozencroft Robert , Guest Brogan , Straeten Catherine Van Der , Fiorentino Francesca , Cobb Justin
Published: March 2022

Background: Advantages of hip resurfacing arthroplasty over total hip arthroplasty include the preservation of the thigh bone, reduction in the risk of dislocation due to the large size of the ball, revision surgery being easier, and higher activity level in younger participants. However, metal-on-metal hip resurfacings has been shown to cause higher metal ion levels and some participants reported progressive pain leading to early revision. By exchanging the metal material of the bearing with BIOLOX®delta ceramic, the main cause of early revision is removed. The H1 Implant is innovative both in its anatomical shape and in its materials as there is currently no all-ceramic, completely cementless hip resurfacing implant in clinical use. Methods: This is a multicentre, prospective, non-randomized, observational study to evaluate the clinical outcome of the H1 System, which consists of the H1 Implant and the H1 Instruments. The intended application of the H1 Implant is to replace the diseased areas of the articular surface and restore joint function. The aim is to recruit 250 participants. Adult participants up to the age of 70 years will be recruited and followed-up for 10 years from the date of surgery. All operative complications, both intraoperative and postoperative through discharge will be collected. Any complication, whether device-related, surgery related or otherwise, will be collected and reported where applicable. The assessment of the safety and performance characteristics as well as establish the superiority of the ceramic-on-ceramic bearing couple of the H1 Implant will be evaluated and compared to metal-on-metal hip resurfacings in the literature.Discussion: This study protocol describes the H1 Clinical Investigation. The protocol was designed by clinicians, experienced trialists and patients, in order to test the safety and performance of The H1 System. Trial registration: ISRCTN registry with study ID ISRCTN91554748
CT-Navigated Percutaneous Posterior Positioning of Pedicle Screws in The Cervical Spine
Authors: Keil Holger , Kreinest Michael , Grützner Paul Alfred , Vetter Sven Yves
Published: March 2022

Background To evaluate reliability, practicability and precision of a novel intraoperative computed tomography(iCT)-based (Airo mobile CT scanner, Brainlab, Munich, Germany) navigated procedure to minimally-invasive positioning of cervical pedicle screws.Methods Ten consecutive patients that suffered from a cervical traumatic instability needing posterior fixation were included in this retrospective analysis. Posterior pedicle screws were positioned iCT-navigated percutaneously. After positioning of the screws, a control scan was performed to assess screw placement and correction if needed. All CT scans were randomly evaluated by two investigators with experience in skeletal CT diagnostics. In the iCT scans, positioning of the screws regarding affection of the medial pedicle cortex as well as the neuroforamina were measured. Additionally, image quality was evaluated with a subjective Likert-Scale (0-5) and a semi-objective Assessability score (0-4).Results 44 screws were placed in an average duration of surgery of 139min [83-209]. The average subjective image quality was 3.9 [2-5], the average assessability score was 3.7 [2-4]. 27 screws (61%) were positioned exactly centered in the pedicle. 4 screws perforated the medial wall by more than 2mm [2.8-2.9]. 9 screws were positioned laterally by more than 2mm [2.5-4.9]. No postoperative neurological deficits were observed.Conclusion iCT-navigated percutaneous placement of pedicle screws is a rather safe and reliable method for posterior fixation of the cervical spine that allows fixation of traumatic cervical instabilities with minimal additional trauma. Even in shallow anatomic structures, visualization of instruments and implants allows for minimally invasive surgery.
The Biological Behavior of High-Grade Glioma in H3K27M Mutant Circumscribed Midline Gliomas
Authors: Li Zhi , Li Hainan , Tan Jieyun , Lai Mingyao , Chen Wendan , Liu Minting , Zhou Zhaoming , Deng Dabiao , Cheng Baijie , Fan Chongzuo , Cai Linbo
Published: March 2022

Purpose: Due to the prognosis of circumscribed midline gliomas（CMGs）with H3K27M mutation is still unclear. This study explored the prognostic stratification of （CMGs） with H3K27M mutation.Methods: One hundred and sixty midline gliomas（MGs）were identified over 10 years. Immunohistochemistry was done for H3K27M, ATRX, IDH1, and P53, and Sanger sequencing performed for IDH and H3 genes. The clinicopathological characteristics were reviewed and survival analysis performed.Results: 1. For H3K27M mutant MGs, there was no difference in prognosis between diffuse midline gliomas (DMGs) and CMGs (p = 0.211), also between the CNS WHO grades.2. The prognosis of H3K27M mutant CMGs of CNS WHO grade 1 was worse than that of H3K27M wild-type CMGs (p = 0.0024), even worse than of DMGs without H3K27M mutation of CNS WHO grade 2(p = 0.0066).Conclusions: The weight value of H3K27M affecting prognosis is affected by location and age. CMGs with H3K27M mutation have biological behavior similar to high-grade gliomas. It is recommended that Treatment management was referenced to high-grade glioma for CMGs with H3K27 mutation.
Recording and Modeling the Seasonal Growth of Suaeda Heteroptera at Liao River Estuary, China, Based on the Wetland Image Monitoring System (WIMS)
Authors: Wang Yicong , Liang Xianmeng , Yu Yang , Yu Changbin , Yang Min , Wu Guojun
Published: March 2022

Wetland ecology monitoring is an important technical guarantee for the protection and restoration of fragile wetland environments. In view of the degradation of the functional vegetation Suaeda heteroptera ( S. heteroptera ) in the Liao River Estuary wetland, an online monitoring method named the Wetland Image Monitoring System (WIMS) was established to obtain real-time, continuous, high spatial and temporal resolution data about the area and height of S. heteroptera . Based on the monitoring data, we confirmed the best model to describe the change process of the area and height for S. heteroptera . The results showed that the growth of S. heteroptera could be divided into three stages: in April and May, the area and height of the S. heteroptera increased rapidly; from June to September, the growth rate slowed down; after October, the area and height of S. heteroptera gradually stabilized. The modeling results showed that the Bertalanffy model had the best simulation performance on the change of the area. While for the height simulation, the segment model composed of the linear and Gompertz models could effectively reduce the simulation error and improve the fit accuracy compared with the single model. In addition, the WIMS has the potential to capture other important ecological factors in small regions, such as benthic animals, birds, waterlogging condition, etc. This observing method can provide high-resolution and abundant data for further exploration of the degradation of typical ecosystems under climate change and human activities.
Efficacy and safety of substitute vincristine with vindesine in R-CHOP- like regimen in the treatment of newly diagnosed DLBCL, a real-world study
Authors: Sun Xiao-Hong , Wan Shun , Bai Xiao-Teng , Li Zi-Jian
Published: March 2022

Background The replacement of doxorubicin with other anthracyclines like epirubicin, pirarubicin, or liposomal adriamycin in the R-CHOP regime showed non-inferiority for DLBCL. Replacing vincristine with vindesine (R-CHVP) in R-CHOP has rarely been compared in efficacy and safety. This study aimed to figure out whether R-CHVP was non-inferior to R-CHOP in both efficacy and toxic effects.Methods This is a retrospective study performed at The First Hospital of Lanzhou University, including all consecutive adult patients aged over 18 years with newly diagnosed DLBCL who received therapy with R-CHOP or R-CHVP from March 2008 to September 2020. We compared the efficacy and safety of the R-CHVP regimen with vincristine and the R-CHOP regimen with vindesine.Results We identified 56 patients with DLBCL, including 18 patients in R-CHOP, 7 in R-CTOP, 12 in R-CEOP, 17 in R-CEVP, 11 in R-CTVP. Complete response was achieved in 12(66.7%), 4(57.1%), 5(41.7%), 7(41.2%) and 4(36.4%) patients respectively. The ORR of the five different schemes is 83.3%, 85.7%, 66.7%，64.07%，and 81.8%, respectively. The most common hematological adverse events during induction were anemia and neutropenia, and the most common non-hematological toxicity are gastrointestinal symptoms and neurotoxicity. The comparison of adverse events between R-CEOP and R-CEVP groups is as follows: the toxicity of hematological adverse events was not statistically significant; among non-hematological toxicity, the R-CEVP group was superior to the R-CEOP group in peripheral neuropathy (p=0.026). The 2-year progression-free survival were 75.5%, 54.6%, 53.2%, 62.7% and 42.4% in R-CHOP, R-CTOP, RCEOP, R-CEVP and R-CTVP group respectively.Conclusion The R-CHVP, in which vincristine was substituted by vindesine, was not inferior to the standard R-CHOP regimen and showed less neurotoxicity. Treatment regimens composed of different anthracyclines have similar therapeutic benefits and adverse events in addition to cardiotoxicity.