bluuebunny/crossref_metadata_2025 huggingface dataset:
Carbon—Carbon Bond‐Forming Enantioselective Synthesis of Chiral Organosilicon Compounds by Rhodium/Chiral Diene‐Catalyzed Asymmetric 1,4‐Addition Reaction.
Authors: Shintani Ryo , Okamoto Kazuhiro , Hayashi Tamio
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Palladium‐Catalyzed Allylic Transposition of (Allyloxy) Iminodiazaphospholidines: A Formal [3,3]‐Aza‐phospha‐oxa‐Cope Sigmatropic Rearrangement for the Stereoselective Synthesis of Allylic Amines.
Authors: Lee Ernest E. , Batey Robert A.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A Novel Synthesis of Unsymmetrical Selenides via the Cleavage of Se—Se Bond by Sm/cat.CoCl2 System.
Authors: Chen Rener , Su Weike , Zhong Weihui
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
1‐Alkoxyallene as an Effective Precursor for Regio‐ and Stereocontrolled Allylation Reactions with Aliphatic Aldehydes via Bis‐Stannylation.
Authors: Williams David R. , Fultz Micheal W.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Cespitulactams A, B, and C, Three New Nitrogen‐Containing Diterpenes from Cespitularia taeniata May.
Authors: Shen Ya‐Ching , Lin Yun‐Sheng , Kuo Yao‐Haur , Cheng Yuan‐Bin
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Application of a Domino Intramolecular Enyne Metathesis/Cross Metathesis Reaction to the Total Synthesis of (+)‐8‐epi‐Xanthatin.
Authors: Kummer David A. , Brenneman Jehrod B. , Martin Stephen F.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Illudalane Sesquiterpenoids, Echinolactones A (I) and B (II), from a Mycelial Culture of Echinodontium japonicum.
Authors: Suzuki Shinsuke , Murayama Tetsuya , Shiono Yoshihito
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Enantioselective Total Synthesis of Isoedunol (I) and β‐Araneosene (II) Featuring Unconventional Strategy and Methodology.
Authors: Kingsbury Jason S. , Corey E. J.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Pelseneeriol‐1 and ‐2: New Furanosesquiterpene Alcohols from Porostome Nudibranch Doriopsilla pelseneeri
Authors: Gaspar Helena , Gavagnin Margherita , Calado Goncalo , Castelluccio Francesco , Mollo Ernesto , Cimino Guido
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Structures and Absolute Configurations of Three 7,8‐Secolabdane Diterpenes from the Chinese Liverwort Pallavicinia ambigua
Authors: Li Zi‐Jing , Lou Hong‐Xiang , Yu Wen‐Tao , Fan Pei‐Hong , Ren Dong‐Mei , Ma Bin , Ji Mei
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Exploiting PdII and TiIII Chemistry to Obtain γ‐Dioxygenated Terpenoids: Synthesis of Rostratone (I) and Novel Approaches to Aphidicolin (II) and Pyripyropene A (III).
Authors: Justicia Jose , Oltra J. Enrique , Cuerva Juan M.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A Facile Domino Metathetic Route to a Thapsigargin Skeleton.
Authors: Kaliappan Krishna P. , Nandurdikar Rahul S.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Sterically Biased 3,3‐Sigmatropic Rearrangement of Azides: Efficient Preparation of Nonracemic α‐Amino Acids and Heterocycles.
Authors: Gagnon David , Lauzon Sophie , Godbout Cedrickx , Spino Claude
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Highly Sensitive Peptide‐Based Probes for Protein Tyrosine Phosphatase Activity Utilizing a Fluorogenic Mimic of Phosphotyrosine.
Authors: Mitra Sayantan , Barrios Amy M.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Design, Synthesis, and Evaluation of Octahydropyranopyrrole‐Based Inhibitors of Mammalian Ribonucleotide Reductase.
Authors: Fuertes Michael J. , Kaur Jaskiran , Deb Prasant , Cooperman Barry S. , Smith Amos B. III
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Chiral 2‐C‐Methylene Glycosides and Carbohydrate‐Derived Pyrano[2,3‐b][1]benzopyrans: Synthesis via InCl3‐Catalyzed Stereoselective Ferrier Rearrangement of 2‐C‐Acetoxymethyl Glycal Derivatives.
Authors: Ghosh Rina , Chakraborty Arijit , Maiti Dilip K. , Puranik Vedavati G.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Heteroaryl‐O‐glucosides as Novel Sodium Glucose Co‐Transporter 2 Inhibitors. Part 1.
Authors: Zhang Xiaoyan , Urbanski Maud , Patel Mona , Zeck Roxanne E. , Cox Geoffrey G. , Bian Haiyan , Conway Bruce R. , Beavers Mary Pat , Rybczynski Philip J. , Demarest Keith T.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Secondary Fungal Metabolites. Part 65. Concavine, an Unusual Diterpenic Alkaloid Produced by the Fungus Clitocybe concava.
Authors: Arnone Alberto , Bava Adriana , Fronza Giovanni , Nasini Gianluca , Ragg Enzio
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A Domino Amidation Route to Indolines and Indoles: Rapid Syntheses of Anhydrolycorinone, Hippadine, Oxoassoanine, and Pratosine.
Authors: Ganton Michael D. , Kerr Michael A.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
New Asymmetric Approach to Natural Pyrrolizidines: Synthesis of (+)‐Amphorogynine A (Ia), (+)‐Amphorogynine D (Ib), and (+)‐Retronecine (II).
Authors: Roche Caroline , Kadlecikova Katarina , Veyron Amael , Delair Philippe , Philouze Christian , Greene Andrew E. , Flot David , Burghammer Manfred
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of Phosphonate Analogues of the Antiviral Cyclopropane Nucleoside A‐5021.
Authors: Onishi Tomoyuki , Sekiyama Takaaki , Tsuji Takashi
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
New and One Pot Chemoselective Synthesis of Nucleoside 5′‐H‐Phosphonate Diesters.
Authors: Guo Xin , Jiang Peng , Fu Hua , Jiang Yuyang , Zhao Yufen
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Electrooxidative Glycosylation Through C—S Bond Cleavage of 1‐Arylthio‐2,3‐dideoxyglycosides. Synthesis of 2′,3′‐Dideoxynucleosides.
Authors: Mitsudo Koichi , Kawaguchi Takashi , Miyahara Seiji , Matsuda Wataru , Kuroboshi Manabu , Tanaka Hideo
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A New Modular and Practical Methodology for the Synthesis of 4‐ or 3‐Substituted Phenyl C‐Nucleosides.
Authors: Hocek Michal , Pohl Radek , Klepetarova Blanka
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of Sphingosine Relatives. Part 27. Synthesis and Absolute Configuration of 6‐Hydroxylated New Ceramides in Human Skin, Ceramides B, 4, 7 and 8.
Authors: Masuda Yui , Mori Kenji
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
An Asymmetric Synthesis of (‐)‐Prelactone B.
Authors: Salaskar Avinash A. , Mayekar Narayan V. , Sharma Anubha , Nayak Sandip K. , Chattopadhyaya Angshuman , Chattopadhyay Subrata
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
An Efficient Asymmetric Synthesis of Grenadamide.
Authors: Green Rachel , Cheeseman Matt , Duffill Sarah , Merritt Andy , Bull Steven D.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis and Structural Revision of Marine Eicosanoid Agardhilactone.
Authors: Miyaoka Hiroaki , Hara Yoshinori , Shinohara Ikuo , Kurokawa Takao , Yamada Yasuji
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Bioactive Phenolic Compounds from a Medicinal Lichen, Usnea longissima.
Authors: Choudhary Muhammad I. , Azizuddin Azizuddin , Jalil Saima , Atta‐ur‐Rahman Atta‐ur‐Rahman
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
F2928‐1 and ‐2, New Antifungal Antibiotics from Cladobotryum sp.
Authors: Kanai Yoshinori , Tatsumi Yoshiyuki , Tokiwa Toshiyuki , Watanabe Yoko , Fujimaki Tsukasa , Ishiyama Daisuke , Okuda Toru
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A New Fungicide Produced by a Streptomyces sp. GAAS7310
Authors: Chen Guangying , Lin Birun , Lin Yongcheng , Xie Fengchun , Lu Wen , Fong Wang‐Fun
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Absolute Configuration of TPU‐0043, a Pentaene Macrolide from Streptomyces sp.
Authors: Igarashi Yasuhiro , In Yasuko , Ishida Toshimasa , Fujita Tsuyoshi , Yamakawa Takashi , Onaka Hiroyasu , Furumai Tamotsu
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
1‐Hydroxy‐1‐norresistomycin, a New Cytotoxic Compound from a Marine Actinomycete, Streptomyces chibaensis AUBN1/7.
Authors: Gorajana Adinarayana , Kurada Bapiraju V. V. S. N. , Peela Sujatha , Jangam Premkumar , Vinjamuri Saisha , Poluri Ellaiah , Zeeck Axel
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Structure Elucidation of Sch 725674 from Aspergillus sp.
Authors: Yang Shu‐Wei , Chan Tze‐Ming , Terracciano Joseph , Loebenberg David , Patel Mahesh , Chu Min
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Enantioselective Total Synthesis of the Polyketide Natural Product (‐)‐EI‐1941‐2: A Novel Interleukin‐1β Converting Enzyme (ICE) Inhibitor.
Authors: Mehta Goverdhan , Roy Subhrangsu
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Enantioselective Synthesis of Apoptolidinone (I): Exploiting the Versatility of Thiazolidinethione Chiral Auxiliaries.
Authors: Crimmins Michael T. , Christie Hamish S. , Chaudhary Kleem , Long Alan
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of the Marine Sponge Derived β2‐Adrenoceptor Agonist S1319.
Authors: Fairhurst Robin A. , Janus Diana , Lawrence Annabel
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Biologically Active Secondary Metabolites from Fungi. Part. 21. X‐Ray Structure Determination, Absolute Configuration and Biological Activity of Phomoxanthone A.
Authors: Elsaesser Brigitta , Krohn Karsten , Floerke Ulrich , Root Natalia , Aust Hans‐Juergen , Draeger Siegfried , Schulz Barbara , Antus Sandor , Kurtan Tibor
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Magnetoelectric Phenomena in Single‐Phase and Composite Systems
Authors: Mitoseriu Liliana
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Chemical Modification and Fabrication of Composite Particles for Metallic Iron and Its Oxides
Authors: Hu Y. , Wang Y. L. , Hao L. Y. , Gong X. L. , Zhang X. Z. , Jiang W. Q. , Zhang P. Q. , Chen Z. Y.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Advances in Nb3Sn Strand for Fusion and Particle Accelerator Applications
Authors: Parrell Jeffrey A. , Field Michael B. , Zhang Youzhu , Hong Seung
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Experimental and Theoretical Approaches to the Study of TMI‐Zeolite (TM: Fe, Co, Cu)
Authors: Berthomieu Dorothee , Jardillier Nicolas , Delahay Gerard , Coq Bernard , Goursot Annick
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Preparation and Application of Ammine Complexes of Precious Metals
Authors: Komoda Yasunobu
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Five‐, Six‐, and Seven‐Membered Lactim Ethers. Methods of Synthesis and Chemical Properties
Authors: Shvekhgeimer M.‐G. A.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Non‐Conventional Methodologies for Transition‐Metal Catalyzed Carbon—Carbon Coupling: A Critical Overview. Part 1. The Heck Reaction
Authors: Alonso Francisco , Beletskaya Irina P. , Yus Miguel
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Supported Ionic Liquid Catalysis
Authors: Mehnert Christian P.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
High‐Throughput Heterogeneous Catalytic Science
Authors: Hendershot Reed J. , Snively Christopher M. , Lauterbach Jochen
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
The Synthesis of the Antimalarial Natural Product Polysphorin and Analogues Using Polymer‐Supported Reagents and Scavengers
Authors: Zanardi Franca , Appendino Giovanni , Casiraghi Giovanni
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Carbon Nanotubes in Electron Donor—Acceptor Nanocomposites
Authors: Guldi Dirk M. , Rahman G. M. A. , Zerbetto Francesco , Prato Maurizio
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Development of Novel Nickel‐ and Palladium‐Catalyzed Cycloaddition Reactions which Proceed with High Atom Economy
Authors: Saito Shinichi
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Drug—Drug Interaction of Antifungal Drugs
Authors: Niwa Toshiro , Shiraga Toshifumi , Takagi Akira
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
The Development of Asymmetric Diamination of Alkenes with Imido‐Osmium Reagents
Authors: Muniz Kilian
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Heteroditopic Receptors
Authors: Itsikson N. A. , Zyryanov G. V. , Chupakhin O. N. , Matern A. I.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Methods of Synthesis and Properties of Hexanitrohexaazaisowurtzitane
Authors: Sysolyatin S. V. , Lobanova A. A. , Chernikova Yu. T. , Sakovich G. V.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Supramolecular Porphyrin Complexes
Authors: Mamardashvili G. M. , Mamardashvili N. Zh. , Koifman O. I.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
The Discovery of Novel Metal‐Induced Reactions of Nitrones: Not only Electrophiles and Reagents for [3 + 2] Cycloadditions
Authors: Cardona Francesca , Goti Andrea
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Adolf von Baeyer: Winner of the Nobel Prize for Chemistry 1905
Authors: de Meijere Armin
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Peptides on a New Path. Scientists from Leipzig Combine Biochemistry, Semi Conductor Physics and Theory
Authors: Goede Karsten , Grundmann Marius , Holland‐Nell Kai , Beck‐Sickinger Annette G. , Bachmann Michael , Janke Wolfhard
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Poly‐sialic Acid: Structure and Properties
Authors: Janas Tadeusz , Janas Teresa
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Order‐disorder Conformational Transition of Xanthan Gum
Authors: Viebke Christer
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Rheological Behavior of Polysaccharides Aqueous Systems
Authors: Lefebvre Jacques , Doublier Jean‐Louis
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Direct Synthesis of Dimethyl Carbonate from CO2 and Methanol
Authors: Wu X. L. , Shu D. , Meng Y. Z.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
The Willgerodt‐Kindler Reaction: Some Probable Reaction Pathways
Authors: Darabi H. R. , Aghapoor K.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Selective Photooxygenation of Alkenes by Zeolite Confinement
Authors: Stratakis M.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Calixarene Complexes with Transition Metal Ions
Authors: Sliwa Wanda
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
End‐functionalized Poly(bisphenol A Carbonate) Oligomers. Part I: Synthesis and Examples
Authors: Korn Michael R.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Cyclic Peptides Containing Biaryl and Biaryl Ether Linkages
Authors: Feliu Lidia , Planas Marta
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of Peptide Bioconjugates
Authors: Hudecz Ferenc
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Backbone Amide Linker Strategies for the Solid‐Phase Synthesis of C‐Terminal Modified Peptides
Authors: Alsina Jordi , Kates Steven A. , Barany George , Albericio Fernando
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
High‐Throughput Peptide Synthesis
Authors: Lebl Michal , Hachmann John
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A Modular Approach to DNA‐Programmed Self‐Assembly of Macromolecular Nanostructures
Authors: Gothelf Kurt V. , Brown Raymond S.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Recycling Solid Wastes as Road Construction Materials: an Environmentally Sustainable Approach
Authors: Kassim Tarek A. , Simoneit Bernd R. T. , Williamson Kenneth J.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Illuminating Zinc in Biological Systems
Authors: Lim Nathaniel C. , Freake Hedley C. , Brueckner Christian
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Molekül‐Detektive. Biosensoren
Authors: Stöcklein Walter
Published: February 2006

Biosensoren sind Messfühler, die durch eine enge Kopplung von einem biologischen Erkennungselement (Rezeptor) und einem Signalumwandler (Transducer) gekennzeichnet sind. Sie profitieren vor allem von der hohen Selektivität, mit der Analyte nachgewiesen werden können. Blutzuckermessgeräte für die Patienten‐Selbstkontrolle sind ein Paradebeispiel für erfolgreiche Biosensoren. Andere Biosensoren haben sich als Teil eines Analysensystems bewährt, zum Beispiel die Sensorchips von Oberflächenplasmonresonanz‐ oder Interferometrie‐ basierten Geräten. Zu den Biosensoren, die Analytmoleküle direkt ohne Hilfsreagenzien nachweisen können, gehören auch die Piezosensoren. Thermometrische Sensoren ermöglichen den direkten enzymatischen Nachweis von Analyten, ohne dass ein optisch oder elektrochemisch nachweisbares Produkt entstehen muss. Der Herstellung von Biosensor‐Oberflächen, die ein hohes Verhältnis von spezifischem zu unspezifischem Signal ermöglichen, wird durch neue Techniken ermöglicht, wie das Beispiel der Nanoröhren zeigt. Mit der preisgekrönten Entwicklung von Chips, die Tausende bis Millionen Sensoroberflächen tragen und als DNA‐, Protein‐Chips oder Mikroarrays bezeichnet werden, beginnen sich biosensorische Prinzipien zu etablieren.
Cantharidin: Hochzeitsgabe, Schutz‐ und Lockstoff, Blasenzieher und Enzymhemmer
Authors: Eiden Fritz
Published: February 2006

Zahlreiche Pflasterkäferarten dient das in ihrem Blut enthaltene Cantharidin als Schutz‐ und Lockstoff. Als Arzneimittel und Aphrodisiakum wurden cantharidinhaltige Käfer (und später der Wirkstoff Cantharidin) von der Antike bis zur Mitte des 20. Jahrhunderts verwendet, wobei der Nutzen allerdings wegen der hohen Toxizität begrenzt war. Von der Isolierung des Wirkstoffs Cantharidin über die Aufklärung seiner Struktur bis zum Aufspüren praktikabler Synthesewege vergingen anderthalb Jahrhunderte. In neuerer Zeit hat das Cantharidin wegen seiner Hemmwirkung auf den Zellstoffwechsel regulierende Enzyme (Proteinphosphatasen) wieder das Interesse vieler Molekularbiologen, Pharmakologen und Chemiker gefunden.
Chemisches bei Caesar. De bello Gallico...
Authors: Volke Klaus
Published: February 2006

Caesar benennt in seinem “Gallischen Krieg” verschiedene Materialien, bei deren Erzeugung chemische Kenntnisse vonnöten waren; sei es das Eisen für die Waffen, den Waid als Körperbemalung oder den Wein. Es wird der Kenntnisstand zurzeit der Römer bei der Herstellung dieser und anderer Produkte dargestellt, wobei insbesondere auf die Historia naturalis von Plinius d. Ä. Bezug genommen wird. Es wird deutlich, dass es sich lohnt, die Werke der antiken Autoren aus chemiehistorischer Sicht zu betrachten.
Mit dem Mikroskop Chemie erleben. Reaktionen von Kupfer‐Ionen
Authors: Kirch Sandra , Decker Frank , Schlick Christian , Wolfer Elmar , Schmidt Oliver , Hausknecht Jennifer , Sitzmann Helmut
Published: February 2006

Am Beispiel der Reaktionen von Kupfer(II)‐Ionen mit Reduktionsmitteln, Fällungsreagenzien oder Komplexbildnern werden die Vorteile des Experimentierens unter dem Mikroskop veranschaulicht. Typischerweise im Wassertropfen, manchmal moderiert durch Zusatz von Kieselgel, zeigt sich die Natur im Mikroskop von einer besonders schönen Seite. Nebeneffekte der beschriebenen Methode sind die Einsparung von Chemikalien sowie eine Verringerung der Abfallmenge und des Risikos.
Konfigurationsbestimmung der Chinasäure
Authors: Siebert Carsten D.
Published: February 2006

Die (–)‐Chinasäure kommt als Naturstoff isomerenrein vor und obwohl die absolute Konfiguration bekannt ist, kann sie mit den gängigen Stereodeskriptoren R und S nicht beschrieben werden. Dieser erstaunliche Sachverhalt ist zwar nicht neu, aber dennoch wenig beachtet worden. Der Beitrag zeigt die Grenzen der gebräuchlichen stereochemischen Terminologie auf.
Wettlauf zum E‐Papier
Authors: Borchard‐Tuch Claudia
Published: February 2006

Schnell schaltbar wie ein Bildschirm, flimmerfrei wie bedrucktes Papier: Mehrere Unternehmen kreieren elektronisches Papier – Folien aus Kunststoff, welche veränderbare Texte und Grafiken darstellen können.
Kuba – Improvisationstalent gefragt
Authors: Groß Michael
Published: February 2006

Wir befinden uns im Jahr 2006 n. Chr. Die ganze Welt ist von den Kapitalisten besetzt ... Die ganze Welt? Nein! Eine von unbeugsamen Kubanern bevölkerte Insel hört nicht auf, den Globalisierern Widerstand zu leisten ... Nun, die Weltpolitik mag sich ein wenig verändert haben, seit Julius Caesar Gallien eroberte und das Dorf von Asterix und Obelix umzingelte, doch auch heute noch gilt: wer klein ist und einen übermächtigen Gegner hat, der ihm den garaus machen will, muss eine Extraportion Einfallsreichtum mitbringen.
Doch Malaria‐Impfung?
Authors: Jaenicke Lothar
Published: February 2006

Die Malaria ist noch immer, nach der DDT‐Desillusion sogar wieder steigend, ein Armutszeichen unserer Globalgesellschaft, aber auch eines, das zeigt, auf wie vielfältige Weise sich Natur‐ und Therapie gegenseitig die Waffen aus der Hand schlagen. Auf der einen Seite haben sich Resistenzen gegen fast alles Aussichtsreiche und Erschwingliche entwickelt, auf der anderen sind Um‐ und Holzwege beschritten worden, die den Spürsinn der Forscher nicht loslassen und – vielleicht bricht die Mauer eher als der Kopf, wie steter Tropfen den Stein höhlt.
Unter der Tiefsee
Authors: Jaenicke Lothar
Published: February 2006

Chemische Prozesse im Tiefseemeeresboden‐Porenwasser, durch die das Ökosystem bis hinauf zur Ozean‐ und Erdoberfläche tiefgreifend beeinflusst wird, stammen aus Tätigkeit lebender Bakterien, sind also rezent und im wahren Sinn rezent biochemisch. Ein wesentliches Beispiel ist die fermentative Bildung von Methan(hydraten), sein Aufsteigen in die Tropo‐ und Atmosphäre mit den Folgen auf das Klima.
Elevated serum level of YKL‐40 is an independent prognostic factor for poor survival in patients with metastatic melanoma
Authors: Schmidt Henrik , Johansen Julia Sidenius , Gehl Julie , Geertsen Poul F. , Fode Kirsten , von der Maase Hans
Published: February 2006

BACKGROUND

YKL‐40 is a growth factor for connective tissue cells and stimulates migration of endothelial cells. Cancer cells, macrophages, and neutrophils secrete YKL‐40. Its function in cancer is unknown. High serum YKL‐40 levels have been associated with a poor prognosis in patients with several solid tumors. The prognostic impact of serum YKL‐40 in metastatic melanoma was evaluated.

METHODS

YKL‐40 was measured in serial serum samples from 110 patients with metastatic melanoma obtained immediately before and during treatment and from 245 healthy subjects.

RESULTS

Patients had higher serum YKL‐40 values than healthy subjects (P < 0.001). Pretreatment serum YKL‐40 was elevated in 45% of the patients and correlated to site of metastases (P = 0.03) and poor performance status (P = 0.002). Multivariate Cox analysis showed that serum YKL‐40 (hazard ratio [HR] = 1.9; 95% confidence interval [CI], 1.2–2.8; P = 0.004) and serum lactate dehydrogenase (LDH) (HR = 1.9; 95% CI, 1.2–2.9; P = 0.004) were independent prognostic factors for survival. A combination variable of elevated serum YKL‐40 and LDH quadrupled the risk of early death (HR = 4.4; 95% CI, 2.5–7.7; P < 0.001) compared with patients with normal levels. The combination of YKL‐40 and LDH had a stronger prognostic impact than the American Joint Committee on Cancer (AJCC) Stage IV classification. Furthermore, serum samples were available from 12 patients during followup. In 9 of 11 patients a significant increase in serum YKL‐40 was observed together with disease progression. In one patient with a lasting complete response, serum YKL‐40 remained normal.

CONCLUSIONS

An elevated serum YKL‐40 was an independent prognostic factor for poor survival in patients with metastatic melanoma. When combining serum YKL‐40 and LDH, patients could be separated into three prognostic groups based on the number of elevated biomarkers. The findings should be validated in an independent study. Cancer 2006. © 2006 American Cancer Society.
Critical analysis of prostate‐specific antigen doubling time calculation methodology
Authors: Svatek Robert S. , Shulman Michael , Choudhary Pankaj K. , Benaim Elie
Published: February 2006

BACKGROUND

Prostate‐specific antigen (PSA) doubling time (PSADT) has emerged as an important surrogate marker of disease progression and survival in men with prostate carcinoma. The literature is replete with different methods for calculating PSADT. The objective of the current study was to identify the method that best described PSA growth over time and predicted disease‐specific survival in men with androgen‐independent prostate carcinoma.

METHODS

PSADT was calculated for 122 patients with androgen‐independent prostate carcinoma using 2 commonly used methods: best‐line fit (BLF) and first and last observations (FLO). Then, PSADT was calculated by using both a random coefficient linear (RCL) model and a random coefficient quadratic (RCQ) model. Statistical analysis was used to compare the ability of the methods to fit the patients' PSA profiles and to predict disease‐specific survival.

RESULTS

The RCQ model provided the best fit of the patients' PSA profiles, as determined according to the significance of the added parameters for the RCQ equation (P≤ 0.002). The PSADT estimates from the FLO method, the RCL model, and the RCQ model were highly significant predictors (P< 0.001) of disease‐specific survival, whereas estimates from the BLF method were not found to be significant predictors (P= 0.66). PSADT estimates from the RCQ and RCL models provided an improved correlation of disease‐specific survival (both R2= 0.55) compared to the FLO (R2= 0.11) and BFL (R2= 0.003) methods.

CONCLUSIONS

Random coefficient methods provided a more reliable fit of PSA profiles than other models and were superior to other available models for predicting disease‐specific survival in patients with androgen‐independent prostate carcinoma. The authors concluded that consideration should be given to applying the RCL or RCQ models in future assessments of PSADT as a predictive parameter. Cancer 2006. © 2006 American Cancer Society.
Expression of FasL in squamous cell carcinomas of the cervix and cervical intraepithelial neoplasia and its role in tumor escape mechanism
Authors: Ibrahim Ramy , Frederickson Helen , Parr Allyson , Ward Yvona , Moncur Joel , Khleif Samir N.
Published: February 2006

BACKGROUND

To date, several mechanisms have been described by which malignant cells escape from the immune system. One of these is through the expression of FasL. The authors hypothesized that the Fas/FasL interaction enables cervical carcinoma cells to induce apoptosis of the cells of the immune system and thereby escape from them.

METHODS

The authors tested the expression of FASL on the surface of cervical carcinoma tissues. Next, they stained the same cervical tissues with anti‐human leukocyte common antigen and TUNEL to identify apoptotic cells. An in vitro functional assay was then done to test if the FASL expressed on the surface of cervical carcinoma cell lines was or was not responsible for inducing apoptosis in T‐cells. Finally, they compared the expression of FASL on normal and dysplastic cervical tissues.

RESULTS

Ninety‐four percent of the cervical carcinoma tissues the authors tested expressed FasL and the majority of the apoptotic cells in the specimens were leukocytes with very few tumor cells. In the in vitro functional assay, only the Fasl expressing cell line and not the Fasl negative cell line was able to induce apoptosis of the Fas‐expressing Jurkat cells. On examining the normal cervical tissues, the authors found that the expression of Fasl was confined to the basal cell layer with loss of expression observed in the suprabasal layers, which made it an immune privileged site. Conversely, there was persistent expression of FasL in the dysplastic layers in cervical dysplasia and squamous cell carcinoma specimens.

CONCLUSIONS

The findings of the current study support the authors' hypothesis that persistent expression of FasL plays a role in the ability of cervical carcinoma cells to escape from the immune system. Cancer 2006. Published 2006 by the American Cancer Society.
Second autologous or allogeneic transplantation after the failure of first autograft in patients with multiple myeloma
Authors: Qazilbash Muzaffar H. , Saliba Rima , De Lima Marcos , Hosing Chitra , Couriel Daniel , Aleman Ana , Roden Linda , Champlin Richard , Giralt Sergio A.
Published: February 2006

BACKGROUND

Most patients undergoing high‐dose therapy and autologous transplant for multiple myeloma eventually develop a disease recurrence. However, to the authors' knowledge, the optimal salvage treatment for these patients is not well defined. Both autologous and allogeneic hematopoietic stem cell transplantations have been used for salvage therapy. The outcomes of salvage autologous or allogeneic transplants were analyzed retrospectively in patients relapsing after an autograft.

METHODS

Fourteen patients (median age, 52 yrs) received a second autograft for salvage, whereas 26 patients (median age, 51 yrs) underwent a reduced‐intensity allogeneic transplantation (related in 18 patients and unrelated in 8 patients). The median interval between the first and the second transplant was 25 months in the autologous group and 17 months in the allogeneic group. The two groups were evenly matched with regard to other disease characteristics.

RESULTS

After a median follow‐up of 18 months for the autologous group and 30 months for the allogeneic group, the median progression‐free survival (PFS) and overall survival (OS) in the 2 groups were 6.8 months versus 7.3 months and 29 months versus 13 months, respectively. Acute and chronic graft versus host disease (15%) was the most common cause of nonrecurrence mortality in the allogeneic group and infections (14%) in the autologous group. On univariate analysis, an interval of > 1 year between the first and the salvage transplant predicted a better OS in the allogeneic group.

CONCLUSIONS

Both autografting and allografting are feasible as salvage therapy for myeloma patients who develop disease recurrence after the first autograft, although disease progression remains the major cause of failure. Better approaches are needed for salvage therapy in patients developing disease recurrence after an autograft. Cancer 2006. © 2006 American Cancer Society.
Nuclear expression of the antiapoptotic protein survivin in malignant melanoma
Authors: Ding Yiling , Prieto Victor G. , Zhang Peter S. , Rosenthal Seth , Smith Kathleen J. , Skelton Henry G. , Diwan A. Hafeez
Published: February 2006

BACKGROUND

Expression of the antiapoptotic protein survivin has been demonstrated in some melanocytic lesions and is believed to be required for melanoma cell viability. However, its diagnostic value in differentiating melanomas from nevi has not yet been examined.

METHODS

Tissue microarray blocks were constructed with paraffin‐fixed tissue of 19 nevi, 18 dysplastic nevi, 24 malignant melanomas, and 31 metastatic melanomas. Sections were then reacted with three antisurvivin antibodies (two monoclonal and one polyclonal) assessing labeling intensity (absent or weak, and moderate to strong) as well as the percentage of cells labeled (< 25%, ≥ 25%).

RESULTS

Of the antibodies evaluated, the polyclonal one was found to be the most sensitive. Nuclear immunoreactivity for survivin (i.e., ≥ 25% of cells exhibiting and/or at least moderately intense staining) was seen in a subset of melanomas but not in nevi or dysplastic nevi (P < 0.05)

CONCLUSIONS

Survivin is variably expressed in the cytoplasm in the entire spectrum of melanocytic lesions, with nuclear expression detectable only in melanomas. These data may underscore the importance of nuclear survivin in progression to melanoma and may prove useful in the differential diagnosis of melanoma versus nevus. Cancer 2006. © 2006 American Cancer Society.
Potential Energy Surfaces of the Microhydrated Guanine⋅⋅⋅Cytosine Base Pair and its Methylated Analogue
Authors: Zendlová Lucie , Hobza Pavel , Kabeláč Martin
Published: February 2006

A complete scan of the potential and free‐energy surfaces of monohydrated and dihydrated guanine⋅⋅⋅cytosine and 9‐methylguanine⋅⋅⋅1‐methylcytosine base pairs was realized by the molecular dynamics/quenching technique using the force field of Cornell et al. implemented in the AMBER7 program. The most stable and populated structures localized were further fully reoptimized at the correlated ab initio level employing the resolution of identity Møller–Plesset method with a large basis set. A systematic study of microhydration of these systems using a high‐level correlated ab initio approach is presented for the first time. The different behavior of guanine⋅⋅⋅cytosine and adenine⋅⋅⋅thymine complexes is also discussed. These studies of nucleic acid base pairs are important for finding binding sites of water molecules around bases and for better understanding of the influence of the solvent on the stability of the structure of DNA.
Unlocking the learning potential in peer mediation: An evaluation of peer mediator modeling and disputant learning
Authors: Harris Robert D.
Published: February 2006

This research used modeling theory to test peer mediator modeling and disputant learning during peer mediation.The results demonstrated that peer mediators effectively modeled, and disputants effectively learned, conflict resolution knowledge, attitudes, and skills that contributed to a significant improvement in conflict attitudes and behaviors, and a significant reduction in disputant discipline problems following mediation.
The murky world of mediation ethics: Neutrality, impartiality, and conflict of interest in state codes of conduct
Authors: McCorkle Suzanne
Published: February 2006

Mediator ethics is an area of controversy. This article reports a study of national and state codes of conduct that found significant differences across the entities in their views of mediator neutrality, impartiality, conflict of interest, and dual role relationships.
Dialogue and democracy, community and capacity: Lessons for conflict resolution education from Montessori, Dewey, and Freire
Authors: Hedeen Timothy
Published: February 2006

Teachers and trainers of conflict resolution are heirs—if often unwitting ones—to a rich legacy in education; not just any education, but a tradition of furthering democracy within learning environments and throughout society. Whether in an elementary school classroom or graduate school seminar, a prison cafeteria or church basement, a corporate boardroom or community center gymnasium, conflict resolution education continues this tradition.
Linking theory to practice: A theory of change model of the Natural Resources Leadership Institute
Authors: Addor Mary Lou , Cobb Tanya Denckla , Dukes E. Franklin , Ellerbrock Mike , Smutko L. Steven
Published: February 2006

The Natural Resources Leadership Institute (NRLI), a leadership development program for capacity building in environmental decision making, cultivates a cadre of leaders who address environmental problems collaboratively and creatively. Describing our theory of change model, this article introduces why and how the NRLI works, the theoretical perspectives that support the NRLI, and the outcomes that result when these theories are put into practice in North Carolina and Virginia.
Creating awareness of the spiritual dimensions of conflict resolution by contemplating organizational culture
Authors: Lichtenstein Marsha
Published: February 2006

Conflict resolution training for faith‐based groups asks members to look at how to integrate their group's specific rituals, practices, and values into a reconciliation process and uncover the deeper, taken‐for‐granted meanings of these features of spiritual life. However, faith‐based organizations differ significantly along several dimensions. Conflict resolution training must take into consideration both the commonalities and distinctions among faith‐based groups.