bluuebunny/crossref_metadata_2025 huggingface dataset:
The Utility of Bone Marrow Aspirate Injection in Comminuted Femur Fractures: Does it Improve Functional and Radiological Outcomes?
Authors: Kapoor Pranav , D’ Souza Albert , Gautam Virender Kumar , Mathiyalagen Prakash
Published: January 2025

Objectives

The study aimed to analyze the functional and radiological outcomes of prophylacticbone marrow aspirate injections (BMAI) in closed comminuted diaphyseal femur fractures treated with closed reduction internal fixation (CRIF) and compare it to those treated only with definitive fixation.

Material and Methods

Forty patients with closed comminuted diaphyseal femur fracture were enrolled and divided equally into two groups. The case group (n=20) prophylactically received bone marrow aspiration injection (BMAI) post 2 weeks of CRIF, and the control group (n=20) received CRIF treatment alone, without BMAI. The lower extremity functional scale (LEFS) and radiological criteria were employed to evaluate the output in both groups.

Results

Graphical representation of categorical variables showed a significant difference (p<0.05) at 26 weeks of follow-up. Delayed union was seen in 10% of patients from the case group and 45% of patients from the control group. Complications were minimal in the case group when compared to the control group (0% vs. 5%). The estimated LEFS score for the case group (68.592+0.524) was significantly higher than that of the control group (66.433+0.524) up till the 20th week. However, by the 26th week, there was no significant difference between the two groups, indicating that while BMAI accelerates recovery, the long-term functional outcomes might converge over time. The percentage of maximal function was higher for the BMAI group than for controls.

Conclusion

The reduced incidence of delayed union in the BMAI group demonstrated that BMAI significantly lowers the risk of delayed healing. The absence of non-unions in the BMAI group further supports the effectiveness of the BMAI in healing, both radiologically and functionally.
GLOBAL STABILITY AND HOPF BIFURCATION OF A DELAYED PREDATOR-PREY MODEL INCORPORATING ALLEE EFFECT AND FEAR EFFECT
Authors: Abdulqadr Didar Akram , Mustafa Arkan Nawzad
Published: January 2025

This paper aims to discover the impact of the fear of predators in prey, Allee effect for predator reproduction and time delay corresponding to the gestation period on the dynamics of a predator- prey model. Existence, non-negativity, and boundedness of the model solutions are guaranteed. The criteria for asymptotically stability of all the biologically feasible steady state points are determined. It is also determined a critical value for time delay, where the model under goes Hopf -bifurcation near coexistence steady state point. Finally, with the help of the MATLAB program, to confirm the analytical results and discover the impact of fear, the Allee effect, and time delay, the model was solved numerically.it is observed that fear affect negatively on both prey and predator species and the time delay may system may induce a transition of the dynamics of system from the a stability situation to the state where the populations oscillate periodically or vice versa
Antik Dönem Karya Bölgesi (Muğla) Süstaşları / Gemstones of the the Caria Region (Muğla) in the Antient Period
Authors: Çoban Evrim
Published: January 2025

Çalışmanın amacı, M.Ö. 1.100 yılı itibariyle M.Ö. 545’e kadar hükümdarlığını sürdüren Karya Uygarlığının kullandığı gemolojik ürünlerin (süstaşlarının ve süstaşlı takıların), Karya bölgesinden elde edilen süstaşları ile karşılaştırılması ve arkeo-gemolojik kapsamlı takı kullanımlarını araştırmaktır. Karya bölgesi kazılarından çıkarılan eserlerin korunarak saklandığı Milas Arkeoloji Müzesi ve Bodrum Sualtı Arkeoloji Müzesi’nde bulunan çeşitli takılar üzerindeki süstaşları ilk kez yalnız sanatsal açıdan değil bilimsel olarak ta arkeo-gemolojik açıdan incelenerek envanterlerinin ortaya konması gerçekleştirilmiştir. Bodrum Sualtı Arkeoloji Müzesi ve Milas Müzesi’nde bulunan ve Muğla bölgesinden elde edildiği düşünülen süstaşlarından yalnızca dumanlı kuvarstan üretilmiş antik ürünler bulunmuştur. Bununla birlikte yüksek olasılıkla ticari yollar ile Lidya bölgesinden getirilen sardoniks, ayrıca Hindistan ve Yemen bölgelerinden geldiği düşünülen süstaşları ve cam ile seramik türü süstaşı olarak kullanılan materyaller de tespit edilmiştir.
Methods of detecting lesions of upper motor neuron in amyotrophic lateral sclerosis using transcranial magnetic stimulation
Authors: Bakulin Ilya S. , Poydasheva Alexandra G. , Chernyavsky Andrey Yu. , Suponeva Natalya A. , Zakharova Maria N. , Piradov Mikhail A.
Published: January 2025

Introduction. Coexistent involvement of upper and lower motor neurons is a characteristic feature of amyotrophyc lateral syndrome (ALS) necessary for the diagnosis. Diagnosis of upper motor neuron involvement in ALS is based solely on clinical features, which may not be detected at the disease onset and in rare forms manifesting clinically as the local lower motor neuron syndrome (LLMNS). The main method of assessment of the functional state of the upper motor neuron in ALS is transcranial magnetic stimulation (TMS). It allows assessing the excitability of motor cortex, corticospinal path function, and mapping of cortical representation of the muscles. In patients with ALS changes of various indicators demonstrating hyperexcitability as well as degenerative lesions of the motor cortex and the corticospinal tracts are recorded on TMS.
Objective: to discuss changes in the TMS in patients with LAS, pathophysiological mechanisms of their formation and possible diagnostic value.
Results. In 22 patients with LLMNS, navigation TMS revealed disturbances of intracortical suppression on paired stimulation with recording period of silence, increase of motor threshold in dominant hemisphere, decrease of the weighted square and reorganization of cortical representations of the hand muscles.
Conclusion. The data obtained allow to consider navigation TMS as a promising technology for identifying upper motor neuron involvement in patients with ALS.
РЕМАРКИ К СТРАТЕГИЧЕСКОМУ ПЛАНИРОВАНИЮ СЕВЕРО-ВОСТОКА РОССИИ: КАМЧАТСКИЙ ВЕКТОР
Authors: Соломонов М.П.
Published: January 2025

Это вторая в серии статей автора о регионах Северо-Восточного мезорегиона России по их действующим стратегиям социально-экономического роста после командировок в эти регионы в 2023 г. и изучения литературы в рамках государственного задания Минобрнауки РФ. Ремарки приведены к стратегическому планированию Камчатского края с позиции «взгляда со стороны». Это может не относиться к Камчатскому краю, но не секрет, что иные стратегии регионов или муниципальных образований формируются самими работниками исполнительной власти регионов и местного самоуправления. Природная жемчужина планеты – Камчатский край может еще сохранить свой потенциал возобновляемых ресурсов если, приоритетом стратегического управления краем останутся традиционные отрасли народного хозяйства: рыболовство и сельское хозяйство, а также охрана окружающей среды полуострова. Индустриализация традиционных отраслей наряду с развитием энергетики на основе возобновляемых источников энергии и с развитием дорожно-транспортной сети полуострова может реализоваться при системообразующем хозяйственном участии государства и края.
МЕТОДИЧЕСКИЙ ПОДХОД К ОЦЕНКЕ ИНДИКАТОРОВ РАЗВИТИЯ ПРОФЕССИОНАЛЬНОГО ОБРАЗОВАНИЯ
Authors: Шапошников В.А. , Логинова С.Л.
Published: January 2025

Статья отражает предварительные результаты авторского исследования по методологии прогнозирования профессионального образования. В ходе исследования различных факторов, влияющих на развитие профессионального образования, для определения количественной оценки уровня их влияния, были выбраны индикаторы, характеризующие развитие профессионального образования. Опираясь на экспертную оценку методом ранжирования, были выявлены наиболее значимые индикаторы, которые в дальнейшем могут быть использованы для составления прогноза развития профессионального образования
ОПРЕДЕЛЕНИЕ ИСТОЧНИКОВ ИНФОРМАЦИОННОГО НАПОЛНЕНИЯ СИСТЕМ УЧЕТА ОБЪЕКТОВ ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ В СУБЪЕКТАХ РОССИЙСКОЙ ФЕДЕРАЦИИ
Authors: Русов С.Л.
Published: January 2025

Условия, в которых должно происходить создание систем учета объектов интеллектуальной собственности (ОИС) во вновь интегрируемых с Россией регионах, характеризуются отсутствием достаточной материальной базы, информационных ресурсов и дефицитом кадрового потенциала в этой сфере. Для решения этого вопроса были исследованы существующие в России региональные системы учета ОИС с целью выявления информационных источников их наполнения. В ходе проведенных исследований были выявлены регионы, информационные карты сведений которых могли бы быть приняты за образец для вновь присоединенных российских регионов. По итогу исследований был составлен рейтинг информационных карт, учитывающий объем содержащихся в них сведений об этих объектах (информационные показатели). Лидирующее место в этом рейтинге заняли информационные карты сведений, утвержденные приказом Минобрнауки России, которые предназначены для информационного наполнения ЕГИСУ НИОКТР. Использование именно таких карт в качестве модельных для систем учета ОИС в новых регионах России позволит повысить объем сведений об ОИС, а, соответственно – качество и разнообразие аналитических отчетов о состоянии сферы в регионе.
Phosphorylated Sporopollenin as a Sustainable Catalyst for Selective 5-Hydroxymethylfurfural Formation in Water: Insights into Phosphate Functionalization, and Mechanism
Authors: Sharma Raina , Selvaraj Tamilmani , Vijayendran Gowri , Varghese Jithin John , Jayamurugan Govindasamy
Published: January 2025

Metal-free Brønsted acid catalysts in water often lead to undesirable side reactions, complicating the synthesis of 5-hydroxymethylfurfural (5-HMF). As a result, organic heterogeneous catalysts with high selectivity for 5-HMF are highly sought after. Hence, this study uses sporopollenin (exine) as a heterogeneous support. 31P CP/MAS NMR showed that conventional H3PO4 cleaning of spores not only produces empty sporopollenin (ESP) but also functionalizes it with mono- and di-phosphoesters (41:59). This functionalized ESP, termed ESP-Phos, serves as a selective catalyst for the formation of 5-HMF from glucose. By activating ESP-Phos at 200 °C, the di-phosphoester ratio increases to 29:71, improving 5-HMF yield (92%) and selectivity (96%) in H2O. DFT calculations reveal strong glucose interactions with di-phosphoester, explaining enhanced catalysis. Mechanistic studies involving isotopic labelling, 13C NMR, and DFT calculations suggest direct glucose dehydration to form 5-HMF. Despite humin deposition causing deactivation, calcining at 200 °C restores catalytic activity. This method is environmentally friendly and suitable for large-scale 5-HMF production.
Electron Density Redistribution as a Descriptor for Excited-state Reactivity
Authors: Guerra Cristian
Published: January 2025

The present work introduces a novel framework to ana- lyze excited-state reactivity by leveraging the redistribution of electron density between two states. This methodology builds upon and extends the Quantum Theory of Atoms in Molecules (QTAIM) and state-specific density partition- ing to characterize reactive sites in excited molecules. By employing the electronic redistribution function ∆ρij (r), we demonstrate its ability to delineate reactive sites, de- scribe bond formation dynamics, and predict photoprod- ucts across diverse molecular systems. Examples include the [2+2] cycloaddition of ethylene, the Paternò–Büchi re- action, and thiocarbonyl-initiated cycloadditions, each ex- hibiting distinct electronic redistribution patterns that gov- ern their excited-state behavior. Furthermore, ∆ρij (r) ef- fectively captures reactivity near conical intersections, offer- ing new insights into degenerate regions of potential energy surfaces. This approach provides a unifying descriptor for excited-state reactivity, bridging classical chemical intuition with a quantum mechanical approach, and sets the stage for developing predictive models for complex photochemi- cal systems.
Controlled/"Living" Click Polymerization with Possible Bi-Directional Chain-Growth Propagation during Polyaddition
Authors: Sakai Satoshi , Nakamura Takuya , Uchiyama Mineto , Kubo Tomohiro , Kamigaito Masami , Satoh Kotaro
Published: January 2025

In this work, we found a new class of controlled/"living" polymerization system, which proceeds bidirectional fashion using click reaction of AB monomer bearing azide and alkyne functionalities in a single molecule. The click polymerization of the AB monomer proceeded well using both azide and alkyne initiators in a well-controlled manner in either growth direction to afford polymers with predetermined molecular weights and narrow molecular weight distributions as well as the terminal structures inherited from the initiator. Especially, the polymerizations with the difunctional initiators provided well-defined linear polymers with azide or alkyne groups at both termini. This approach also allows for polymerization control over the second monomer to give a block copolymer.
Enhanced Crystallinity of Tetrahalopyridyl (THP) Derivatized Compounds
Authors: Begg Callum , Dragomanova Viktoriya , Yufit Dmitry , Blundell Toby , Cobb Steven , Fox Mark , Kitching Matthew , Brittain William
Published: January 2025

Promoting the formation of ordered crystalline material is a fundamental challenge in the fields of organic synthesis, crystal engineering and wider material science. Traditional approaches typically employ strong, unidirectional intermolecular interactions as the core princi-ples for tecton and synthon design. In contrast, the interactions between complex biomolecules, such as proteins, take advantage of the cooperativity of multiple, weak, polyaxial non-covalent interactions (NCIs), working in concert, to generate strongly associated super-structures. Such design principles have yet to be successfully applied to small molecule crystal engineering. Here we show that the tetra-halopyridyl (THP) unit fulfils these tectonic criteria. Firstly, vast and varied THP based NCIs are identified within the Cambridge Struc-tural Database (CSD). The diversity of NCIs is then validated through manual interrogation of a model library and quantified through quantum topological analyses using Bader’s Atoms In Molecules (QTAIM), non-covalent interactions – reduced density gradient (NCI-RDG) and natural bond orbital (NBO) approaches. Furthermore, the critical importance of F···F interactions is revealed through analysis of 17 pairs of interactions in a diverse library of 12 related scaffolds. The utility of the approach is then shown across a wide variety of substrates including promoting natural product crystallinity and for application in absolute structural determination
Water molecules in the cannabinoid receptor 2 binding site crucially impact the discovery of novel ligands
Authors: Scharf Magdalena M. , Scott-Dennis Morgan , Borrega-Roman Leire , Giese Franziska N. Z. , Plevako Darya , Sykes David A. , Veprintsev Dmitry B. , Kolb Peter
Published: January 2025

The cannabinoid receptor 2 (CB2R) is of considerable therapeutic and scientific interest. Hence, the discovery of novel molecules that target and modulate this receptor, ideally selectively over its closest relative, the cannabinoid receptor 1, is of great importance. In this study, we aimed to discover novel ligands targeting the CB2R using large library in silico docking screens. However, since the CB2R binding site is difficult to target with in silico methods due to its hydrophobic nature, we used a variety of screening approaches, including the placement of water molecules in predicted water sites of the receptor binding site, and screening against multiple docking setups and receptor conformations. We systematically evaluated these different approaches to support future screens to the CB2R and other receptors. In the present work, each setup contributed different ligands of varying intrinsic activities, leading to an overall improved hit rate compared to that of a single screen. Of the novel ligands of the CB2R discovered and experimentally confirmed in this study, one series features high-affinity ligands with a previously undescribed scaffold.
Optimization of Theoretical Models and Impact of Basis Sets on Infrared Intensities of the trans-1,2-C2H2F2 Molecule
Authors: Faria Sergio
Published: January 2025

This work addreses the analysis of fundamental infrared intensities and dipole moment derivatives of the trans-1,2-C2H2F2 molecule. The study aims to understand discrepancies between theoretical and experimental results by exploring the impact of basis sets and electronic correlation levels. Small basis sets, such as 6-31G, showed greater accuracy for high-intensity vibrational modes, such as CF stretching, due to their ability to capture simple geometric changes. Theoretical models based on DFT (B3LYP and M06L) and ab initio methods (MP2 and CCSD) were compared using metrics such as mean absolute deviation (MAD) and root mean square error (RMS). Results indicated that smaller basis sets are more suitable for describing normal stretching modes, minimizing errors and artificial effects introduced by excessive polarization functions. Additionally, the NC-NCF-O model based on MP2/6-31G(d,p) proved to be robust for determining dipole moment derivatives, yielding the lowest MAD and RMS. The study also analyzed the F2CS molecule, confirming the effectiveness of small basis sets for high-intensity vibrational modes. In conclusion, the choice of basis set is critical for accurate modeling of infrared intensities, and smaller basis sets often outperform larger ones, particularly for well-defined and localized vibrational modes.
Relación entre procrastinación académica y rendimiento académico: una revisión sistemática, periodo 2020 -2024
Authors: Olivos Romero Mariela Angélica
Published: January 2025

El propósito de este estudio es analizar la relación entre la procrastinación académica y el rendimiento académico en estudiantes entre 2020 y 2024. Utilizando el método PRISMA, se realizó una revisión sistemática de artículos científicos provenientes de bases de datos como Scopus, WoS y SciELO. La selección se basó en artículos revisados por pares, con un proceso de inclusión y exclusión de estudios. Los resultados mostraron que, de los 10 estudios seleccionados, el 50% encontró una relación moderada entre las variables, el 30% una relación baja, y el 10% indicó que no había relación. Además, se identificó que la procrastinación se relaciona con factores emocionales y conductuales, influyendo indirectamente en el rendimiento académico a través de variables como la ansiedad o la adicción a las redes sociales. En la discusión, se destaca la necesidad de investigar más a fondo la naturaleza de esta relación, particularmente en poblaciones no universitarias, dado que el 80% de los estudios se centraron en estudiantes de educación superior. La conclusión sugiere que la procrastinación académica está vinculada al rendimiento, pero se requiere mayor investigación para determinar la dirección y los factores mediadores de esta relación.
High-resolution analysis of human centromeric chromatin
Authors: Melters Daniël P , Bui Minh , Rakshit Tatini , Grigoryev Sergei A , Sturgill David , Dalal Yamini
Published: January 2025

Centromeres are marked by the centromere-specific histone H3 variant CENP-A/CENH3. Throughout the cell cycle, the constitutive centromere-associated network is bound to CENP-A chromatin, but how this protein network modifies CENP-A nucleosome conformations in vivo is unknown. Here, we purify endogenous centromeric chromatin associated with the CENP-C complex across the cell cycle and analyze the structures by single-molecule imaging and biochemical assays. CENP-C complex–bound chromatin was refractory to MNase digestion. The CENP-C complex increased in height throughout the cell cycle culminating in mitosis, and the smaller CENP-C complex corresponds to the dimensions of in vitro reconstituted constitutive centromere-associated network. In addition, we found two distinct CENP-A nucleosomal configurations; the taller variant was associated with the CENP-C complex. Finally, CENP-A mutants partially corrected CENP-C overexpression–induced centromeric transcription and mitotic defects. In all, our data support a working model in which CENP-C is critical in regulating centromere homeostasis by supporting a unique higher order structure of centromeric chromatin and altering the accessibility of the centromeric chromatin fiber for transcriptional machinery.
200 anos de Independência do Brasil através dos jornais paraenses: audiovisual para o ensino de história no interior da Amazônia
Authors: Sousa Eveline Almeida de , Augusto Isabel Teresa Creão , Melo Vanice Siqueira de , Silva Silvio Lucas Alves da , Aguiar Felipe Xavier
Published: January 2025

Este trabalho compartilha uma das ações do projeto “Educação patrimonial e os lugares de memória em Santarém”, desenvolvido na Universidade Federal do Oeste do Pará (UFOPA), que produziu um material audiovisual para contar a história dos 200 anos de Independência do Brasil, a partir dos jornais paraenses, destinado preferencialmente aos professores e estudantes da educação básica de Santarém (oeste do Pará). Com a proposta de contar a história a partir da realidade amazônica, com sujeitos, documentos e paisagens da região, o vídeo elaborado se configura, ao mesmo tempo, como um recurso didático e uma experiência que leve à reflexão sobre a memória, comunidade e nação, pensando o conhecimento histórico como um dos pilares da formação da cidadania.
Contribuições da Rede UnBcast de Podcasts Universitários à Extensão, à Comunicação Pública e à Inovação
Authors: Pinheiro Elton Bruno , Flexor Carina
Published: January 2025

O presente trabalho tem como objeto de estudo a reflexão analítica sobre o primeiro ano de atuação do Projeto e da Rede UnBcast de Podcasts Universitários. Como eixos de articulação teórica utiliza os conceitos de Podcasting, Comunicação/Radiodifusão Pública, Divulgação Científica, Inovação, Letramento Mediáticoe Extensão. Metodologicamente, o trabalho adota a estratégia da triangulação entre os fundamentos da pesquisa qualitativa, a abordagem descritiva e o relato de experiência. Como resultados, assinala-se que a podosfera universitária tem: a) se consolidado como lócus privilegiado para atos de inovação em mídia sonora; b) se constituído como um dos espaços-tempo protagonistas da divulgação científica e cultural; c) se popularizado como meio de comunicação pública; d) contribuído no campo do letramento mediático e transmediático, na medida em que se constata a capacidade dos(as) jovens universitários como "prosumers" que promovem a partilha e a produção de conteúdos mediáticos de diferentes tipos e níveis de complexidade; e) proporcionado a execução de ações extensionistas como um processo interdisciplinar, educativo, cultural, científico e político.
Eletrificação rural e desenvolvimento local: implantação de sistema híbrido solar hidrocinético numa comunidade na Resex Tapajós-Arapiuns
Authors: Van Els Rudi Henri , Silva Lazaro João Santana da , Mendes Rafael Castilho Faria , Santos Manoel Roberval Pimentel
Published: January 2025

O projeto de extensão “Eletrificação rural e desenvolvimento local” da Universidade de Brasília tem entre os seus objetivos a divulgação e disponibilização de tecnologias de geração decentralizado de energia a partir de fontes renováveis para comunidades rurais e este artigo apresenta os resultados da instalação de um sistema híbrido solar hidrocinética numa comunidade da reserva extrativista de Tapajós-Arapiuns. A metodologia de implantação do sistema envolve o levantamento das demandas energéticas na comunidade, o levantamento do potencial de energia renovável e as ações já empreendidas pela comunidade para aproveitar essa energia, além do processo da escolha da tecnologia e o uso prioritário da eletricidade na comunidade. Como resultado foi instalada na comunidade de Cachoeira de Mentae um sistema solar fotovoltaico de 1360W e uma turbina hidrocinética flutuante de 300W, garantindo assim eletricidade para acesso a internet, iluminação e atendimento das cargas comunitárias na escola, e dessa forma beneficiar toda a comunidade. O desafio agora é emponderar a comunidade para que eles conseguem gerenciar e manter o sistema híbrido e usar a energia como vetor para o seu desenvolvimento local.
A extensão (ou comunicação) em Psicologia como instrumento a um projeto de Psicologia Popular
Authors: Costa Pedro Henrique Antunes da
Published: January 2025

A extensão tem ganhado ganha relevância na formação em Psicologia, enquanto mediação que possibilita um maior “contato com a realidade”, sobretudo a realidade das maiorias populares em um país marcado pela desigualdade social e pronunciadas formas de exploração e opressão. Nesse sentido, tal convocação à Psicologia advém com um chamado também cada vez maior para que ela se (re)pense. No presente artigo, abordamos a relevância da extensão (ou comunicação) para a construção de um projeto de Psicologia Popular. É um trabalho que traz consigo um conjunto de reflexões que nascem de experiências do autor como docente e coordenador de projetos de extensão em Psicologia pela Universidade de Brasília, realizados no Distrito Federal, sobretudo em territórios periféricos, dialogando com iniciativas históricas na Psicologia brasileira – e, em extensão, latino-americana – e outras que atravessaram a Psicologia, oriundas de outros campos do saber-fazer, como a pedagogia e educação popular freireana. Para isso, refletimos sobre que tipo de Psicologia Popular e de extensão queremos, e como a segunda pode – e deve – contribuir à primeira. Todo o processo aqui exposto aponta para que a extensão e a Psicologia, no intuito de fortalecerem a auto-organização, a autodeterminação das maiorias populares na construção do poder popular, sejam tomadas como meios e não fins em si. Acreditamos que podem servir a outras iniciativas extensionistas na e pela Psicologia, bem como à formação e práxis psi como um todo, indo, inclusive para além da própria Psicologia e da extensão, na construção de um horizonte em que não sejam mais necessárias.
Educação em saúde sobre o câncer de pele na atenção básica: um relato de experiência
Authors: Medeiros Carolina Mira Dilly de , Arruda Amanda Cristina da Cunha , Bittencourt Roberto
Published: January 2025

O presente artigo busca descrever a experiência de um projeto de extensão aplicado em uma Unidade Básica de Saúde em Ceilândia – Distrito Federal que buscou promover a conscientização, prevenção e diagnóstico precoce do Câncer de Pele na atenção básica. Partimos do princípio da necessidade de aumentar o conhecimento da população em geral sobre o Câncer de Pele, na medida em que o câncer de pele é o mais frequente no Brasil, responsável por 30% de todos os casos de tumores malignos registrados no País, e a maior parte da população desconhece tal fato. Desenvolvemos ações de educação em saúde, que promoveram a disseminação de conhecimento básico sobre o tema, visando diminuir sua incidência e, consequentemente, a mortalidade. Com a impressão de “gibis” educativos voltado para crianças, confecção de folders e aulas objetivas voltadas para adultos e idosos. Realizamos aproximação com a população, estabelecendo diálogo interativo e dinâmico para fomentar o conhecimento sobre o que é o câncer de pele, sua prevenção, como realizar o autoexame da pele e quando se deve buscar atendimento médico. O trabalho foi realizado com foco em pessoas de todas as idades, incluindo também crianças. Concluiu-se que tal projeto de educação em saúde constitui-se de uma oportunidade de aprendizado, com múltiplos benefícios, tanto para os estudantes de medicina e professores, quanto para a comunidade, assim como, para a equipe de saúde.
Entrevista: Cecilia Iucci
Authors: Iucci Cecilia , Alves Guilherme
Published: January 2025

Entrevista com Cecilia Iucci
Universidad Nacional del Litoral, Argentina. (ciucci@unl.edu.ar)
ORCID: https://orcid.org/0000-0003-0073-2124
Accommodation processes in irradiated steel 12Х18Н10Т during plastic deformation in the temperature range of “dry” SNF storage
Authors:   AL-FARABI KAZAKH NATIONAL UNIVERSITY, Aldabergenova Tamara , Akayev Serik , Dikov Alexey , Larionov Alexandr , Dikova Lyubov
Published: January 2025

This paper presents a detailed study of the fracture surfaces of 12Kh18N10T austenitic stainless-steel specimens subjected to short-term mechanical testing at various temperatures: 24°C, 350°C, and 450°C. The specimens for the study were fabricated from spent nuclear fuel of the BN-350 reactor.

The research was conducted within the framework of a multi-level approach to physical mesomechanics, which allowed for a deeper understanding of the complex processes occurring in the material under different temperature regimes. In particular, a thorough analysis of the changes in the steel's plasticity with increasing test temperature was carried out, revealing a significant dependence of this parameter on the conditions of deformation localization. It was shown that the reduction in plasticity with increasing test temperature is associated with a quasi-uniform distribution of stresses in the zones of deformation localization. These zones of local stress concentration were caused by processes that led to an increase in the material's porosity, which, in turn, was due to accommodation processes of the rotational type.

Thus, the study demonstrated the importance of considering local changes in the material's structure, which can significantly affect its mechanical properties under varying operating conditions. The obtained results may contribute to a deeper understanding of the processes occurring in austenitic steels used in extreme conditions and aid in the development of more reliable materials for use in nuclear and other high-stress systems.
Analysis and comparison of kerosene FTIR spectra using the developed cryogenic-capillary system with low-temperature cell
Authors:   AL-FARABI KAZAKH NATIONAL UNIVERSITY, Kenbay Alisher , Yerezhep Darkhan , Aldiyarov Abdrakhman
Published: January 2025

This work introduces a technology for FTIR spectroscopy of hydrocarbon materials at low temperatures and atmospheric pressure. This device allows to study optical properties of various substances at temperature range of 77 – 300 K without need of a vacuum and to obtain new fundamental data since there is insufficient research in this area. The purpose is to obtain new fundamental insights into the behavior and properties of hydrocarbon fuels under these conditions, as research utilizing this technology remains relatively uncommon. This approach allows for the examination of the optical properties of various substances under atmospheric pressure in the temperature range of 77 to 300 K, without the need for a vacuum environment. The study outlines a method for analyzing hydrocarbons using an infrared (IR) Fourier spectrometer, a diffuse reflection attachment, and two Dewar vessels. One vessel is used for cooling samples with liquid nitrogen inside the cryogenic capillary system, while the second creates an IR-inactive environment where the samples are placed. FTIR spectra of the characteristic C-H functional group peaks in kerosene were obtained, reflecting the types and frequencies of their vibrations in specific wavenumber ranges. These findings can be utilized in cryophysics and cryotechnology laboratories worldwide as proof of the feasibility of such research, supporting the development of similar technologies to acquire new fundamental data on the behavior and properties of various substances at atmospheric pressure and low temperatures.
SYNTHESIS, STRUCTURE AND HIRSHFELD SURFACE ANALYSIS OF THE COMPLEX COMPOUND BASED ON Cd(II) SALT AND O-PHENYLENEDIAMINE
Authors:   AL-FARABI KAZAKH NATIONAL UNIVERSITY, Akhatov Ashur , Turaev Khayit , Ashurov Jamshid , Umbarov Ibragim , Tillaev Xurshidjon , Nomozov Abror , Uralov Nuriddin , Eshdavlatov Erkin
Published: January 2025

In this paper studying the synthesis, crystal structure and Hirschfeld surfaceanalysis of a new complex compound containing [Cd(OPD)3SO4]·H2O obtained based on o-phenylenediamine (OPD) are given. The molecular and crystal structure of this complex compound was determined using the RTT method. In the inner sphere of the complex, twomolecules of OPD in the chelate state and one molecule of OPD in the monodentate state are attached to the central atom. The complex compound forms a distorted octahedral shape in space. [Cd(OPD)3SO4]·H2O complex compound syngonia is monoclinic, space group P21/c and crystal parameters are a=22.5631(5)Å, b=8.1292(2) Å, c=11.6094(4) Å. In the crystal structure of the complex, 5Cd−N (2.350(5) Å−2.448(5)Å) and 1 Cd−O (2.355(5) Å) bonds form an inner sphere. The crystal structure of the molecule is formed by intra-and intermolecular hydrogen bonds of the type N---H...O and O---C...O. In the Hirschfeld surface analysis of [Cd(OPD)3SO4]·H2O complex compound, the main interactions are H...H (54.4%), O...H/H...O (26.7%) and H...C/C...H (16.7%) organizes.
Clinical-epidemiological evaluation of bicipital tendinopathy and medial shoulder instability in dogs (Canis lupus familiaris)
Authors: Trajano Sabrina Cândido , Queiroz Rafael Alexandre , Aragão Breno Bezerra , Silva Jean Carlos Ramos , Tudury Eduardo Alberto
Published: January 2025

Medial shoulder instability (MSI) and bicipital tendinopathy (BT) are important causes of pain and lameness in dogs. Aimed to determine prevalence and risk factor for MSI and BT by clinical orthopedic evaluation of dogs with diverse illnesses treated in the Veterinary Hospital of the Federal Rural University of Pernambuco. Orthopedic examinations were performed for diagnosing MSI and BT. Of the 500 dogs examined, 43.6% were positive for MSI and 15.6% for BT. All dogs positive for MSI showed joint laxity, 70.2% of which were bilateral, of which, 17% were also positive for the mediolateral drawer test and 92.3% also showed bilateral sinking of the greater tuberosity of the humerus in abduction. Of the positive cases for BT, 39.7% had elbow hyperextension above 90º. MSI and BT were more frequent in dogs with orthopedic disorders, with 45.2% and 20.7% respectively. MSI was more prevalent in dogs with acute disease (45.3%), males (48.7%), small dogs (48.7%), elderly (50%) and non-neutered (44.3%), dogs that lived on different floors (48.1%), with access to stairs (43.5%), active (45.6%). For BT, the prevalence was also higher in dogs with acute disease (17.3%), females (16.9%), medium-sized (19%) and adult dogs (17.7%), dogs with access to hardwood floors cement, earth and lawn (17.9%), access to stairs (18.6%), assets (15.9%). There were no variants with statistical significance (p <0.05) for MSI, but for BT there was statistical difference for castrated dogs and patients with orthopedic disorders, who are therefore more predisposed to develop BT.
Актуальні питання психології управління
Authors: Стаднік А. В. , Ващенко І. В. , Мельник Ю. Б.
Published: January 2025

Посібник розроблений у відповідності з програмою військової підготовки офіцерів за військово обліковими спеціальностями "Соціальна психологія" та "Психологія". У другому виданні навчального посібника детально розкриваються теоретичні основи психології управління, характерні риси особистості керівника і підлеглого, основи ділового спілкування і взаємодії, сутність управління груповими процесами, явищами, конфліктними ситуаціями, а також методи і засоби подолання стресів і криз в діяльності керівника. Посібник характеризується чіткістю, логічністю та обґрунтованістю викладення навчального матеріалу, доступністю для сприйняття та засвоєння. Посібник адресується студентам, слухачам, викладачам закладів вищої освіти.
Hybrid Filtering for Student Major Recommendation: A Comparative Study
Authors: Hidayati Nurtriana , Winarti Titin , Hirzan Alauddin Maulana
Published: January 2025

Choosing the right university major is an important decision for students, as delays or incorrect choices can harm their future careers and cause problems for academic departments. High dropout rates, which are frequently the result of poorly informed decisions, can be a considerable burden on faculty. This project aims to address these challenges by creating a recommendation system that provides individualized counsel to students based on their psychological profiles. A quantitative method was used, with questionnaires distributed to a large number of students. To verify the data's authenticity, replies were sought from students who were pleased with their selected majors rather than those who regretted their choices. The collected data formed the basis for a hybrid recommendation system that integrated Content-based Filtering and Collaborative Filtering methods. The system was then compared against standalone implementations of each filtering method to determine its usefulness in increasing suggestion accuracy. The results showed that the Hybrid Filtering strategy obtained a recommendation accuracy of 84.29%, outperforming Content-based  Filtering at 81.43% and Collaborative Filtering at 78.57%. The proposed model is easy to implement in a school or a university, as long as the required data is available. Thus, the model can help a school or university to reduce dropout rates and boost academic outcomes.
SiCitra: Aplikasi Berbasis Web untuk Pemrosesan Citra Digital Menggunakan OpenCV
Authors: Riani Lutfi , Zahra Afnan , Kurniawan Fadly , Valenza Ihsan Lana , Darmansah Fadhlan Zaki , Mindara Gema Parasti , Giri Endang Purnama
Published: January 2025

Penelitian ini membahas perancangan SiCitra, aplikasi berbasis website untuk pemrosesan citra digital menggunakan pustaka OpenCV dan metode waterfall. Aplikasi ini menyediakan fitur manipulasi citra seperti seperti filter warna, deteksi tepi, image processing, rotasi & flip, emboss effect, brightness & contrast, Text Overlay hingga analisis warna melalui antarmuka intuitif. Pengujian menunjukkan kinerja optimal, menjadikannya solusi praktis untuk kebutuhan multimedia, pendidikan, dan penelitian tanpa memerlukan instalasi perangkat lunak tambahan.
Prototipe Rekam Medis Elektronik untuk Mendukung Platform Satu Sehat
Authors: Wardoyo Agung , Abdurakhimov Shokhjakhon , Wulandari Fitria
Published: January 2025

Di masa sekarang, ketika teknologi informasi berkembang dengan pesat, semua sektor akan menghadapi perubahan tersebut secara menyeluruh dan berkesinambungan, sehingga fasiltas yankes diharapkan dapat memberikan kontribusi terhadap perubahan untuk mempermudah serta mempersingkat dalam pertukaran data dan informasi tidak terkecuali rumah sakit sebagai bidang pusat pelayanan di bidang kesehatan, tujuan dari penelitian ini adalah untuk menghasilkan sebuah prototype formulir rekam medis elektronik yang dapat terkoneksi dengan apelikasi satu sehat. Dalam pengembangan prototipe digunakan metode SDLC ( sistem development life cycle), prototyping serta penggunaan usecase diagram untuk menggambarkan interaksi antar pengguna. Dalam pengembangan sistem diperoleh hasil Pada tahap comunication penulis berkomunikasi dengan fasyankes klinik juga memperhatikan alur procedure penjelasan di website satu sehat yang kemudian menerapkan perancangan RME dengan memperhatikan kebutuhan data dan informasi dari plaform satu sehat dari Kementerian Kesehatan, yang terdiri dari form input, form antrian pasien, form Rekam medis, dan form laporan. Berdasarkan hasil pengujian sistem diperoleh hasil pengujian kompabilitas dilakukan dengan menggunakan website powermapper.com. Dari pengujian terdapat 11 page yg teruji dan untuk kompability browser pada ISO masih harus diperbaiki. Sebaiknya digunakan data dari fasyankes untuk ujicoba sistem agar pengembangan sistem sesuai dengan kebutuhan data fasyankes.
The Effect of Home Literacy on Preschoolers' Early Reading Skills
Authors: Kusumawardhani Trully , Dhieni Nurbiana , Yetti Elindra
Published: January 2025

Abstract
Early reading and writing skills, or known as early literacy, is crucial for supporting successful reading and writing during school age. Early literacy is closely related to home literacy, as the two influence each other. However, early reading skills remains low in Indonesia. Therefore, the aim of this study is to determine how home literacy affects the early reading skills of preschool children., both with or without controlling for parental age, occupation, and education. The method used in this study is a quantitative descriptive method using a multiple regression model approach. The samples in this study consist of preschool children and their parents from Little Bee Moslem Kindergarten and Al Kayyisah Kindergarten. Sampling was determined using multistage random sampling. The results of this study show that, with or without controlling for parents' age, parents' occupation, and parents' education, home literacy affects preschool children's early reading skills. All effects were equally influential, except for the impact of constraints on reading with children and the parents' occupation.
Keywords: Early Reading; Home Literacy; Preschool Children
Abstrak
Kemampuan membaca permulaan merupakan kemampuan penting untuk menunjang keberhasilan membaca dan menulis di usia sekolah. Kemampuan membaca permulaan erat hubungannya dengan literasi rumah, karena keduanya saling memengaruhi. Namun kenyataannya, di Indonesia masih rendah kemampuan membaca permulaannya. Tujuan dari penelitian ini untuk mengetahui, bagaimana pengaruh literasi rumah terhadap kemampuan membaca permulaan anak prasekolah. Baik dengan atau tanpa mengontrol usia orang tua, pekerjaan orang tua, maupun pendidikan orang tua. Metode dalam penelitian ini menggunakan metode deskriptif kuantitatif menggunakan pendekatan model multiple regression. Sampel dalam penelitian ini berjumlah 86 dengan rincian 48 anak prasekolah dan 38 orang tua anak prasekolah TK Little Bee Moslem, TK Al Kayyisah. Penentuan sampel dengan menggunakan multistage random sampling. Hasil penelitian menunjukkan bahwa, dengan maupun tanpa mengontrol usia orang tua, pekerjaan orang tua, dan pendidikan orang tua, literasi rumah memengaruhi kemampuan membaca awal anak prasekolah. Semua pengaruhnya sama kecuali pengaruh kendala dalam kegiatan membaca bersama anak dan pekerjaan orang tua.
Kata kunci: Anak Prasekolah; Literasi Rumah; Membaca Permulaan
Dietetic Students’ Changes in Attitudes after Participating in Online Interprofessional Education
Authors: Jackson Kelly , Kurz Terri , Marian Mary
Published: January 2025

Interprofessional education (IPE) is an accreditation requirement and an important component of training for future registered dietitian nutritionists (RDNs) and access to quality IPE is often limited in online programs. An online IPE module was developed to provide dietetics students the opportunity to build collaborative skills with students in other healthcare training programs. A research study was designed to answer the following research question: How and to what extent does participation in an online IPE module impact online dietetics students’ attitudes of interprofessional practice? Participants were dietetics students enrolled in an upper-division online dietetics course. Data gathered included a retrospective pre-post survey, reflection journal entries, and focus group interviews. Results suggested that the online IPE intervention had a positive impact on dietetics students’ attitudes of interprofessional practice and enhanced their understanding of the roles of members of the interprofessional team. The opportunity for participants to work on a final project as part of an interprofessional team likely contributed to the positive shared learning experiences and overall growth in interprofessional collaboration.
A Two-Day Virtual Workshop on the Micronutrient-Directed Nutrition-Focused Physical Exam for Ghanaian Nutrition Professionals: Examining Perceived Self-Efficacy and Innovation
Authors: Qubty Leah , Intiful Freda , Arikawa Andrea , Van Horn Leslie , Wright Lauri
Published: January 2025

Micronutrients are key components of various physiological processes. In Ghana, micronutrient deficiencies are common and medical resources are limited. Biochemical markers of nutrition status are costly and require specialized medical equipment. In the absence of available biochemical markers of nutrition status, the micronutrient-directed nutrition-focused physical exam is a viable tool. This mixed-methods research aimed to determine whether a two-day virtual workshop for Ghanaian nutrition professionals (N=131) would improve perceptions regarding the usefulness and self-efficacy of the micronutrient-directed nutrition-focused physical exam. Quantitative data were collected via a virtual pretest (immediately prior to the workshop) and a virtual posttest (immediately following the workshop). Qualitative data were gathered via focus groups, which were conducted in virtual breakout rooms on the second day of the workshop. Total posttest scores were significantly higher (M=70.15, SE= .703), t(130)= -7.357, p= <.001 than total pretest scores (M= 64.85, SE= .165), t(130)= -7.357, p= <.001. Participants improved their feelings of self-efficacy in performing the NFPE and felt the micronutrient-directed NFPE is an innovative strategy to assess their patient population for MNDs. The success of this virtual workshop speaks to the safety and efficacy of virtual clinical skills training programs.
Challenges of Competency Management for Dietetics Program and Internship Directors: An Application of Design Thinking
Authors: Gaviria David , Chen Elizabeth
Published: January 2025

Objective: Dietetics education transitioned to competency-based education (CBE) in July 2022. Despite its benefits, managing competencies may be a challenging aspect of CBE for dietetics program and internship directors (PDIDs), yet it is unclear what specific aspects of competency management are difficult. Using design thinking, this study sought to capture the impact recent CBE implementation had on PDIDs by identifying specific pain points (i.e., challenges) related to competency management. The results of this work serve to document such pain points and may be used to generate solutions to address or eliminate the pain points. For example, this research can support further development of competency and program management software (CPMS) which exist to support PDIDs with competency management. Methods: Purposive sampling via a U.S.-wide PDID listserv served as the primary recruitment method. The participants (n=17) participated in design thinking activities via focus groups to identify relevant pain points. Themes were identified from the pain points and used to create insights. Results: Competency implementation, tracking, and management were major pain points for PDIDs. These pain points, amongst others, may contribute to the significant job workload PDIDs experience. PDIDs desire support from accrediting bodies to address PDID pain points. Conclusions: This study provides novel information on pain points PDIDs face related to competency management. Many of the pain points reported are addressed by available CPMS, making CPMS a viable option for reducing PDID workload. Future research should document the effect of CPMS and other solutions on reducing the competency management burden.