bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluasi Sistem Pengendalian Intern Penjualan Kredit Berdasarkan Kerangka COSO Pada PT Bussan Auto Finance Cab. Makassar 2
Authors: Syam Shofiana
Published: October 2020

Penelitian ini bertujuan untuk mengetahui apakah sistem pengendalian intern penjualan kredit telah sesuai dengan kerangka COSO. Penelitian ini dilakukan di PT Bussan Auto Finance Makassar 2 mulai bulan April sampai Mei tahun 2020. Desain penelitian yang digunakan adalah jenis penelitian deskriptif kualitatif. Metode analisis yang digunakan adalah kerangka COSO sistem pengendalian intern. Berdasarkan penelitian ini yang peneliti lakukan dapat disimpulkan bahwa sistem pengendalian intern penjualan kredit yang diterapkan di PT Bussan Auto Finance Makassar 2 sudah sesuai dengan kerangka sistem pengendalian intern COSO.
Safety of balanced propofol and midazolam in upper gastrointestinal endoscopy for sedation in cirrhotic patients
Authors: Laima Alam  , Mohammad Asif Khattak  , Mafaza Alam
Published: October 2020

Abstract

Objective: Sedation for upper gastrointestinal endoscopy (UGIE) in patients with cirrhosis is theoretically associated with high incidence of adverse events due to low levels of binding proteins and decreased hepatic clearance of drugs. The objective of the study was to assess the safety of combined propofol and midazolam sedation in cirrhotic patients undergoing UGIE.

Methods: A total of 500 patients undergoing UGIE were divided in to two groups in a prospective observational study from Jan 1st 2018 to June 30th 2018. Group (I) consisted of cirrhotic patients who underwent the procedure with sedation and Group (II) consisted of non-cirrhotic patients who opted for sedation. The main outcome measurements included vitals monitoring before, during and after procedure, total sedation dose, time to initial and deep sedation, recovery time and complications.

Results: There was no significant difference between sedation safety and rate of complications for the cirrhotic and non-cirrhotic patients except for the recovery period during initial 10 minutes. The Modified Aldrete score for the cirrhotic patients was 9.5±0.5 min as compared to 9.8±0.4 min for non-cirrhotic patients (p<0.001) at 10 minutes. Grade 2 hepatic encephalopathy was seen in 0.8% of the cirrhotic patients who required hospitalization for 24 hours. Also balanced sedation was acceptable by the patients and the endoscopists equally with statistically significant scores on endoscopist’s assessment of co-operation and assessment of patient’s satisfaction scores. Continuous...
Perspective of health professionals on hand hygiene in a tertiary care center in Pakistan
Authors: Bari Attia , Izza Imran  , Nasir Ali Nawaz  , Rizwana Kamran  , Iqbal Bano  , Nadia Sadaqat
Published: October 2020

Abstract

Objective: To determine the awareness of postgraduate residents and nurses working in a tertiary care hospital about hand hygiene.

Method: The cross-sectional study was conducted in October 2018 at The Children’s Hospital and the Institute of Child Health, Lahore, Pakistan, and comprised postgraduate residents and nurses. Data was collected using a 31-item self-administered inventory. Data analysis was done using SPSS 21.

Results: Of the 360 subject, 152(%) were postgraduate residents and 208(%) were nurses. Overall score of knowledge 202(56%) was low compared to attitude 260(72%) and practice 283(78.6%). The combined score of all three domains was 245(68%), indicating moderate awareness. Postgraduate residents had significantly better knowledge 98(64%) compared to nurses 104 (50%) (p=0.01), while nurses had better attitude score 159(76.4%) compared to the residents 103(68%) (p<0.05). The practice subscale score was not significantly different between the groups (p>0.05).

Conclusion: Both postgraduate residents and nurses showed moderately satisfactory knowledge, attitude and practice towards hand hygiene.

Key Words: Hand hygiene, Healthcare-associated infections, Postgraduate residents, Nurses, Knowledge, Practices.

Continuous...
Association of apoptotic marker cytokeratin18 with blood pressure in non-alcoholic fatty liver disease patients
Authors: Benash Altaf  , Shireen Jawed  , Rana Muhammad Tahir Salam
Published: October 2020

Abstract

Objective: Non Alcoholic fatty liver disease (NAFLD) associated with hypertension (HTN) is an emerging health issue globally.  It is associated with increased levels of apoptotic marker CK18.  Main objective of this study was to explore association of cytokeratin18 (CK18) with hypertension (HTN) in NAFLD patients.

Methodology: Descriptive cross sectional study was conducted in Mayo hospital Lahore. Hundred NAFLD subjects were enrolled from OPD of radiology department after approval from ethical review committee. Anthropometric measurements were taken and blood pressure (BP) was measured by mercury sphygmomanometer. Blood samples were drawn from each patient for CK18 levels with ELISA. Data was analyzed by SPSS 20. Continuous variables were presented as mean± SD. Association between CK18 and HTN were analyzed by regression analysis and results were presented as ? coefficient. P value<0.05 was taken significant.

Results: Mean age of studied subjects was 43.8±5.34 with height (m), weight (kg) and BMI 1.59±0.063 m, 78.2±11.17 kg, 30.5±4.07kg/m2 respectively. Systolic and diastolic blood pressures were 106±12.8, 72± 12.8mmHg.  CK 18 was not significantly associated with systolic (P value 0.55) and diastolic BP (P value 0.37) most probably due to small size of study.

Conclusion: Most of the NAFLD patients were hypertensive and have raised CK18 levels than normotensive subjects. So, raised levels of CK18 in NAFLD subjects might be helpful in early screening of HTN. However, significant association was not observed probably due to small sample size.

Keywords: CVS, CK18, DBP, HTN, MS, NAFLD, SBP (write full forms for all these abbreviations.

Continuous...
COUPLING CELLULAR AUTOMATA WITH MEDALUS ASSESSMENT FOR THE DESERTIFICATION ISSUE
Authors: Koné Alassane , Fontaine Allyx , El Yacoubi Samira
Published: October 2020

Desertification is one of the major problems affecting our environment in the 21st century. Indeed, it threatens more than 1.5 million people worldwide and affects a quarter of the land in less than 100 countries, it spreads over half a billion hectares per year and reduces the surface water and groundwater. Thus, according to a report by the Food and Agriculture Organisation written in 1993, the direct and visible impacts of desertification are the damage on crops, on livestock, on the electricity productivity, etc. Indirect impacts are lack of food production, poverty, social upheaval, rural exodus to cities. In this paper, our work consists in modelling the degradation process of land whose advanced level leads to the desertification. The first step consists in assessing the degradation of land with the MEDALUS model developed by the MEDALUS project of the commission of the European Union. This model assesses desertification by its sensitivity index which is the geometric mean of four quality factor indexes of soil, vegetation, climate and management (land use). This assessment method uses the major part of the parameters influencing the land degradation process. The second step is to model the land degradation process using cellular automata (CA) approach. For that purpose, the study area will be divided into a regular grid of cells. Initially, each cell has a state (desertification sensitivity index) whose evolution at each discrete time step depends on the states of its neighbours through a built transition function. As a result, this study allows to introduce a dynamical process in MEDALUS model. Indeed, from an initial configuration of an area, the model can predict its evolution over time and space according to a continuous state transition function that extend the classical CA approach and fit to the MEDALUS model parameters.
Cadmium distribution and metallothionein expression in rat organs following acute intoxication
Authors: Fazlieva Anna S. , Usmanova Elza N. , Daukaev Rustem A. , Karimov Denis O. , Valova Yana V. , Smolyankin Denis A. , Baygildin Samat S.
Published: October 2020

Introduction. This article presents the results of experimental simulation of the acute toxic effect of cadmium on the rat organism, its distribution in the liver, and kidneys. Activation of the protective mechanism against toxic metal through the metallothionein protein has to reduce the bioavailability of free cadmium. Material and methods. The study was conducted on rats weighing 140-190 g, which was once intragastrically injected with cadmium chloride in an amount of 1/20 LD50. We studied the time intervals: before intoxication, 1, 2, 4, 6, 24, 48, and 96 hours after inoculation. The accumulation of cadmium in the liver and kidneys was measured by atomic absorption spectrometry. The expression of the metallothionein gene (МТ1, МТ2А, МТ3) was determined using RT-PCR on RNA isolated from the same organs. Results. Quantitative differences in the metal content in the liver and kidneys are observed 1 hour after intoxication, with a cadmium content of 250 and 125 times higher than in the control groups, respectively. There is an accumulation of cadmium in the liver with a maximum after 6 hours, and then its redistribution to the kidneys. The pronounced expression of metallothionein with a single acute exposure to cadmium is tissue-specific, so the expression of the MT1 and MT2A genes was greatest in the liver and the MT3 gene in the kidneys. Discussion. After administration cadmium is mainly localized in hepatocytes and its concentration may exceed the ability of metallothionein to bind cadmium ions, which leads to histopathological changes in the liver. In response to the intake of metal in the cell, the expression pattern of many genes, including those associated with the activation of protective reactions, changes. Conclusion. Our data show a single exposure to cadmium to lead to an increase in the content of MT transcript in the liver and kidneys, simultaneously with the accumulation of metal in them. The nature of this accumulation depends on the organ, on the time of exposure, and gene expression also on the form of MT.
Epidemiological characteristics and hygienic assessment of factors for expanding the areas of pathogens of parasitic diseases on the territory of the Russian Federation
Authors: Kuznetsova Kamalya Yu. , Kuznetsova Maria A. , Abramov Ivan A. , Aslanova Mariya M. , Mania Tamari R. , Sergiev Vladimir P. , Rakhmanin Yury A. , Gorenkov Roman V.
Published: October 2020

Introduction. The high level of trade, population migration, and changes in the infrastructure of economic activity in the regions created the prerequisites for the dispersal and adaptation of parasitic pathogens to new factors, including adverse environmental and climatic conditions of their circulation. For the first time on the example of the distribution of long-term average incidence rates among the four most common parasitic nosological forms, the etiological factor of which is the causative agents of different taxonomic groups, systematized by the type of their circulation in various environmental objects: ascariasis (soil), enterobiosis (household items), opisthorchiasis (fish, products processing), echinococcosis (soil, water, contact with sick animals, processed products of animal raw materials. At the same time, a high level of soil contamination resistance (42.1%), surface runoff (41.8%), surface water (42.5%), sewage sludge (35.1%) characterizes the resistance of the parasitic system to the effects of the existing anthropogenic press on the causative agents of helminth and protozoal infestations and indicates the maintenance of active circulation of pathogens in the environment. Material and methods. The analysis of the average long-term level of parasitic morbidity and changes in the boundaries of the territorial distribution of parasitoses over the past 10 years (2009-2018) in 85 administrative units of the Russian Federation. The epidemiological development trend is determined by the methods of ranking the dynamic series of incidence with categorization by levels relative to the average Russian indices of parasitic incidence and calculation of the linear trend. Results. The calculation data are plotted on the administrative-territorial map of Russia with the help of a GIS program (MapInfo Pro 16) with the allocation of SMPZ levels for each nosology - single, low, medium, high, super high. Conclusion. Calculations of the development of linear trends of medium and low levels, as well as single cases of morbidity, were shown to allow differentiating the development trend of the epidemic process and draw prognostic conclusions.
Impact of the electrochemical treatment on physical and chemical properties of water activated in various devices using electrochemical activation technology
Authors: Nekrasova Larisa P. , Mikhailova Rufina I. , Ryzhova Irina N.
Published: October 2020

Introduction. Currently, there are various technologies for water treatment and water purification, including ozonation of water, water treatment with UV radiation, ion exchange, magnetization. Electrochemical treatment of water by direct electric current, in which activated water is formed, characterized by many anomalous properties, is a modern approach to water treatment and water treatment. Purpose of the study. The study of the physicochemical properties of water-activated in devices of different manufacturers with different designs. Material and methods. To activate the water, activators were used: AP-1, Melesta, Zdrava, the filter of electrochemical water purification “ Izumrud”. The activity of hydrogen ions and the redox potential of water were measured using an Ecotest-120 ionomer with a switch. To measure the electrical conductivity of the solutions, an Expert-002 conductometer was used. Free chlorine was determined by the photocolorimetric method on a Spectroquant Multy colorimeter. Antioxidant activity was determined spectrophotometrically using a mediator system of potassium ferro-ferricyanide. Results. Chloride ions make a decisive contribution to the change in the physicochemical characteristics of anolyte upon activation of water. Sulfates and bicarbonates do not affect the prooxidant activity of the anolyte. The relaxation of catholytes obtained in membrane activators proceeds by a gradual increase in ORP, while the relaxation of activated water in the Zdrava diaphragmless activator proceeds in an oscillatory mode and is characterized by sharp changes in ORP. Anolytes are stable over time and slightly change the pH and ORP during storage. The activation of certain types of water in a diaphragmless activator does not lead to a decrease in the ORP, but its significant growth. Conclusion. Electrochemically activated water is a general term that hides in each case an unknown substance with an unpredictable effect. The use of standard devices even when using the same water sample, as a rule, leads to different physicochemical characteristics of activated water. When using different types of water, physicochemical characteristics differ significantly. The use of electrochemically activated water is unsafe.
Ecological and hygienic assessment of the technogenic reservoir state of the gold extraction enterprise (Zauralye of the Republic of Bashkortostan)
Authors: Baktybaeva Zulfiya B. , Kulagin Andrey A. , Gabidullina Guzel F. , Larionova Tatiana K.
Published: October 2020

Introduction. The population using waste man-made water reservoirs for recreation and providing household needs can be a potential health risk. Such pollutants as heavy metals do not undergo decomposition processes. They accumulate in the biotic and abiotic components of the reservoir. Subsequently, hazardous toxicants can enter the human body through food chains. An ecological and hygienic assessment of the state of the waste reverse reservoir of the Semyonov gold recovery plant has been carried out. Material and methods. The object of the study is located in the Zauralye of the Republic of Bashkortostan at the geographical coordinates 52° 30’20″ N, 58° 19′48″ E. The content of heavy metals (Zn, Cu, Pb, and Cd) in water, bottom sediments and biomass of aquatic macrophyte (Potamogeton perfoliatus L.) was studied. In the bottom sediments, mobile forms of metals have been detected. They are extracted by an acetate-ammonium buffer with pH = 4.8 Results. It has been revealed that in water the concentration of heavy metals is higher than the maximum permissible concentrations for fishery reservoirs: 19-27 times for copper, 10-24 times for zinc, 2.7-5.8 times for lead, 1-1.4 times for cadmium. Exceeding the standards for water bodies for drinking, domestic and cultural water use is recorded for cadmium (6 times) and lead (2.5 times). In bottom sediments, the zinc content of mobile forms is 372.00 ± 28.51 mg/kg, copper - 144.37 ± 4.08 mg/kg, lead - 14.09 ± 1.48 mg/kg, cadmium - 0.036 ± 0.002 mg/kg. The total index (ZC), reflecting the additive excess of the background, is 1686, which corresponds to an extremely high level of man-made pollution of bottom sediments. The concentrations of heavy metals in the aboveground and underground organs of Potamogeton perfoliatus L. are much higher than the background levels. Conclusion. The waste reverse reservoir of the Semenov gold extraction factory is potentially dangerous to the local population health when it is used for breeding poultry, watering cattle, and fishing. The activities aimed at improving the environmental and hygiene situation in the territory of the locality are imperative.
Hygienic assessment of the trace elements content in crop production in an industrially developed region
Authors: Daukaev Rustem A. , Larionova Tatyana K. , Bakirov Ahat B. , Stepanov Evgeny G. , Fazlieva Anna S. , Usmanova Elza N. , Allayarova Guzel R. , Afonkina Svetlana R. , Zelenkovskaya Evgeniya E. , Adieva Gyuzeliya F.
Published: October 2020

Introduction. Agricultural crops grown on garden plots are mainly used for personal consumption, are not subject to safety control, and therefore, the chemical composition of the produced crop products may significantly affect the accumulation or deficiency of chemical elements in the human body. Material and methods. To assess the chemical composition of the main products of plant origin produced in the regions of the Republic of Bashkortostan with different economic specialization, the content of 9 trace elements in carrots, table beets and potatoes was determined by atomic absorption spectrometry (n = 353). Using the total coefficient of anthropogenic load (Ka.n. = ∑Ci/PDUi), the territory of the Republic was ranked according to the degree of contamination of vegetable crops with toxic elements (lead, cadmium). The influence of trace elements contained in crop products on the health of the region’s population was studied using the risk assessment method. Results. Vegetables with a high content of cadmium (10.8% of the analyzed samples) occupy the largest share in the total volume of crop production that does not meet hygiene standards. When ranking the territory of the Republic on the basis of health risk assessment and the degree of contamination of vegetable crops with toxic elements, territories with a developed mining and petrochemical industry were found to be most unfavorable zones. Conclusion. The content of chemical elements in vegetable crops produced on household plots varies in a wide range, depending on the type of plant products and the place of growth. The lack of standards for the permissible content of certain trace elements in food raw materials and food products, which are priority pollutants in a number of regions, and safety control of products produced in private farms increase the risk of consumption of contaminated products by the population.
Impact of a cellphone electromagnetic radiation on phagocytic activity of neutrophils in vitro
Authors: Blyakher Maria S. , Tulskaya Elena A. , Kapustin Ivan V. , Fedorova Irina M. , Nesterenko Vladimir G. , Suslov Anatoly P. , Konopleva Mariya V.
Published: October 2020

Introduction. The nature of a cellphone electromagnetic radiation (EMP) influence on the neutrophils in vitro activation was studied. The relevance of studying the impact of mobile communications and their effects on the body’s physiological processes is determined by the global prevalence of such tools and the research data inconsistency in the both domestic and foreign scientific literature. Material and methods. The object of the study was the whole venous blood samples and isolated neutrophils from 36 adult donors (aged from 22 to 65 years) of both genders. The responses of the neutrophils’ phagocytic activity and its registration were carried out in a flat-bottomed plate for enzyme-linked immunosorbent assay (ELISA), the daily culture of S. aureus ATCC 6538 (strain 209) was used as an inducer of phagocytosis. The intensity of phagocytosis was evaluated by changing the activity of myeloperoxidase (MPO) spectrophotometric method in our modification. Results. In the course of studies of the EMR impact of a cellphone on phagocytic neutrophils, the following was revealed: when culturing neutrophils without the addition of S. aureus, there was a tendency to increase spontaneous MPO activity (by 69%), i.e. its production in the absence of a stimulating factor and, conversely, a significant decrease in the enzyme activity induced by S. aureus (by 34%, p <0.05), i.e. the phagocytic activity of neutrophils. Conclusion We revealed the biological effect of the cellphone EMR as an increase in the spontaneous activity of MPO and a decrease in the bacterially induced activity of the enzyme may indicate a decline in the phagocytic activity of the main cells of the immune system, therefore, it demonstrates a weakening of the protective properties of the human body against infectious diseases. In previous studies, we have shown the presence of the impact of cellphone EMR on the activation of lymphocytes in vitro. The use of immunological tests can be a promising direction in assessing the impact of the cellphone EMR on the human body.
Radiation-hygienic assessment of modern medical technologies
Authors: Okhrimenko Sergei E. , Korenkov Igor P. , Prokhorov Nikolai I. , Shandala Natalya K. , Zakharova Anastasiya V.
Published: October 2020

Introduction. Currently, modern medical radiation technologies, including the use of radiopharmaceuticals, are becoming more widely used. At the same time, it should be noted that these technologies themselves have undergone a significant evolution towards improving their radiation safety. But while radiation technologies have been steadily improving, approaches to controlling and regulating activities with ionizing radiation sources remain highly conservative. In law enforcement practice, this approach leads more and more to excessive requirements that are not justified for the basic principles of radiation safety - rationing, justification, optimization. This paper substantiates the ways to improve the issues of regulation and regulation of activities using modern radiation technologies Purpose of research. Conducting radiation and hygiene assessment of working conditions in PET centers and developing proposals for improving regulatory requirements, taking into account the features of modern technologies Material and methods. Protocols of industrial radiation control, results of own research of effective equivalent doses, equivalent doses for the skin and lens of the eye by thermoluminescent dosimetry, timekeeping of the working time of the PET center staff were used. Results. As part of the work, the results of industrial radiation monitoring of the PET- center of a large medical organization were analyzed. It is shown that the annual radiation doses are within no more than 1/3 of the dose limit for limited personnel, most of whom receive less than 5 mS per year. The data of our research carried out based on the scientific LRC of the Department of radiochemistry of the Lomonosov Moscow State University are in good agreement with the data of the medical institution. Conducting time-lapse studies allowed us to conclude that the time of direct exposure of personnel is significantly less than the standard values provided for by regulatory documents, and the dose rates for many operations can not correspond to the values regulated by these documents. It is shown how a safe technology can relate, on formal grounds, to “highly dangerous”, which is a significant modern contradiction in the field of regulating activities with radiation sources. Conclusion. An important factor in ensuring radiation safety is the identification of critical groups of personnel, the most exposed organs, and tissues, taking into account the annual activity consumed. The standardized dose rate criteria laid down in regulatory documents do not provide for the use of indicators of the actual workload (time of exposure). It is necessary to introduce appropriate changes to the normative documents.
The relationship between different aspects of occupational stress and general health
Authors: Mohammadi S. , Hosseininejad M. , Taghizadeh S. , Kabir-Mokamelkhah E.
Published: October 2020

Introduction. Stress is one of the most common problems at work environments, which may have a negative effect on physical and mental health. Besides, general health problems are the most commonly discussed matter relating to occupational health, causing a reduction in the individual performance quality and work absence. Aims and objectives. The objective of the study was to examine the relationship between the different indicators of occupational stress and general health. Material and methods. This cross-sectional study was conducted among the office workers in Tehran in 2017. HSE’ occupational stress questionnaire was used to develop the different aspects of occupational stress. General health status was determined by General Health Questionnaire (GHQ-12). The relationship between different levels of occupational stress and general health was examined by statistical methods. Results. The study was conducted among a total of 393 participant. The mean scores of occupational stress and general health were 3.23 ± 0.44 and 3.26 ± 2.92, respectively. A significant statistical relationship was observed between general health and the different indicators of occupational stress including role (OR = 10.95, P value <0.001), relationships (OR = 2.73, P value <0.001), manager support (OR = 2.43, P value <0.001), demand (OR = 1.98, P value = 0.001) and organizational changes (OR = 3.03, P value <0.001), suggesting that as the level of occupational stress increased, the level of general health declined Conclusion. Attention to the different indicators of occupational stress and to the efficient ways to avoid and manage it can play an important role in improving the general health status of office workers.
Assessment of periodontal conditions in workers exposed to harmful substances using the micronucleus test
Authors: Zaydullin Iskander I. , Karimova Lilija K. , Kabirova Milyausha F. , Sadrtdinova Guzjal’ R. , Galimova Rasima R. , Valeeva Elvira T.
Published: October 2020

The purpose of this study was to identify the possibility of using a micronucleus test to assess the impact of harmful chemicals on the condition of periodontal tissues of employees of a mining and processing plant. Material and methods. Dental examination was conducted for 40 employees of the mining and processing plant, exposed to harmful substances with an experience of more than 10 years, 36 employees of the plant with a contact time of not more than 10 years, and 46 people with a healthy periodontium. The analysis of buccal epithelial cells for the presence of chromosomal aberrations using the micronucleus test. Results. The prevalence of inflammatory diseases of periodontal tissues in the groups of workers of the plant was 100%. A statistically significant difference was found in the frequency of cells with micronuclei and protrusions of the nucleus in the group of internship workers compared with other groups (p = 0.001). The frequency of cells with two nuclei in the workers of the plant in the groups was at the same level and significantly exceeded the value of the index for a group of people with a healthy periodontium (p = 0.002 and p = 0.006). The frequency of occurrence of cells with vacuolization of the nucleus in a group of workers with an experience of more than 10 years more than doubles that of a group of individuals with a healthy periodontium (p = 0.009). Conclusion. Occupational factors have a significant impact on the development and course of inflammatory periodontal diseases in mining and processing complex employees. Studies using the micronuclear test indicate a negative impact of a complex of harmful substances on the development and course of inflammatory periodontal diseases.
Тelemedicine technologies in occupational health and pathology
Authors: Saiganov Sergey A. , Mazurov Vadim I. , Shilov Viktor V. , Gorbanev Sergey A.
Published: October 2020

Introduction. The article provides legal, organizational, and medical reasons for the feasibility of introducing telemedicine technologies into the practice of occupational health and professional pathology to increase the effectiveness of preventive measures to preserve the health of the working population. Material and methods. Analytical review of data of domestic and foreign literature on modern telemedicine technologies. The aim of the study was to analyze the main directions of development and modern achievements of telemedicine to determine the possibilities for using this type of digital technology in improving the working conditions of workers and preventing professional pathology. Results. The analysis showed that to optimize the search for managerial solutions aimed at preserving the health of the working population of Russia through the large-scale use of telemedicine and information technologies, it seemed necessary: the creation and integration into a single network of telemedicine centers based on professional pathology centers in most constituent entities of the Russian Federation with the head scientific institution - the Center for Occupational Pathology of the Ministry of Health of the Russian Federation for operational coordination of activities; integrate research institutes and higher educational institutions specialized in the field of Occupational Health medicine in major medical centers. Telemedicine technologies make it possible to optimize information interaction and discussion of materials when preparing new regulatory and legal documents with the participation of the main stakeholders: the Ministry of Health, the Ministry of Labor, Federal Service for Oversight of Consumer Protection and Welfare, the Social Insurance Fund, industry unions, etc.; ensure the participation of highly qualified narrow specialists in medical commissions when making expert decisions. Conclusion. Mechanisms for improving the effectiveness of preventive work in Occupational Health using telemedicine technologies will be due to an increase in the quality of medical examinations of workers, an increase in personnel skills, an increase in information security and the speed of expert and managerial decisions, and economic feasibility.
Transcriptional activity of metallothionein genes in acute poisoning caused by cadmium chloride
Authors: Ziatdinova Munira M. , Valova Yana V. , Mukhammadiyeva Guzel F. , Usmanova Elza N. , Karimov Denis O. , Khusnutdinova Nadezhda Yu. , Bajgil’din Samat S.
Published: October 2020

Introduction. Cadmium is one of the most toxic heavy metals widely distributed in the environment. It has a long half-life, leading to its accumulation in various organs, which in turn is the cause of many adverse effects on human health. Material and methods. Acute toxic poisoning with cadmium chloride was simulated on white outbred male rats, divided into groups depending on the exposure time. Samples of liver and kidney tissues were used as study materials, in the homogenate of which the level of mRNA of metallothionein genes was determined. Results. It was found that the maximum value of the multiplicity of MT1 gene expression in the liver was reached after 6 hours (16.36 ± 0.77; p <0.001), and in the kidneys one day after intoxication with cadmium chloride (6.12 ± 0.43; p <0.001). The activity of the MT2 gene in the liver was most pronounced in the range of 2-4 hours (14.35 ± 1.73; 14.78 ± 1.44; p <0.001), while in the renal tissues an increase in the amount of mRNA was recorded after 24 hours (7.32 ± 0.63; p <0.001). The level of MT3 gene transcripts in liver tissues was decreased throughout the experiment, however, the opposite picture was observed in the kidney tissue, where the maximum was reached one day after the administration of the toxicant (6.14 ± 0.31; p <0.001). Conclusion. Thus, an increase in metallothionein expression in response to the presence of heavy metal ions in the body can be used as a genetic marker in case of poisoning with various compounds.
Impact of agronomic management and intensive fertilization on the soils of Panao
Authors:   Ciencias Agrarias -INGENIERÍA AGRONOMICA-UNHEVAL, Vega-Jara Liliana
Published: October 2020

In order to evaluate the impact of long-term agronomic management and intensive fertilization on the soil properties of Pachitea, this study was carried out. Five lots were taken from the province of Pachitea, representative soils of the type of management carried out in this agricultural context. A virgin or pristine soil as absolute control (SV), a soil with less than 20 years of traditional agriculture (SAT1), a soil with intensive fertilization for more than 40 years (SFI), a soil with traditional agriculture between 20-40 years (SAT2), a soil with organic fertilization for more than 40 years (SAO) and a forest soil (SB). Soil samples were taken f rom each 20 cm deep lot and all their physical and chemical properties were analyzed. The results were analyzed in a principal component analysis (PCA), analysis of variance (ANOVA) and regression analysis. The results showed that the agricultural use of the changes changed all the physical and chemical properties of the soil over time. The most sensitive characteristics were pH and organic matter (OM). The changeable acidity (AC) was explained by the presence of Aluminum (Al) and very little by hydrogen (H), suggesting that the degradation of soils is quite strong in this context. Key words: Organic matter, Aluminum, pH https://doi.org/10.47840/ReInA20191
Behavior of the coffee drill (Hypothenemus hampei) before the effects of the biocide Neem (Azadirachta indica) and Higuerilla (Ricinus communis) in the Monzón district, Peru
Authors:   Ciencias Agrarias -INGENIERÍA AGRONOMICA-UNHEVAL, Valverde-Rodriguez Agustina
Published: October 2020

The effects of the biocide Neem (Azadirachta indica) and Higuerilla (Ricinus communis) on the behavior of the bit (Hypothenemus hampei) were evaluated in coffee plantations of the Limani variety in the district of Monzón, Huánuco, Peru at 1100 masl. 2 doses of each biocide (1L and 4L of Neem extract / 20LH2O, 1L and 4L of Higuerilla extract / 20LH2O) were used (absolute control), with frequency of applications at 8 days and sampling at 5 days after each application in the stage of flowering and maturation of the coffee fruits. Among the results, it is observed that the 4L dose of Neem / 20LH2O extract presents a lower percentage of infestation (2.13%), a lower number of brocade cherry trees (1.67) in contrast to the control treatment (10.83%), in terms of the number of bits per cherry tree, minimum ranges of bit are recorded (1 to 1.33) being exceeded by the witness (7.50 bits / cherry), in the possession of attack the B is recorded (1 to 2.75 "bits" is in the penetration channel, that is to say, in the mesocarp of the coffee fruit), as well as the control with possession D (13 "bits" inside the seed and eggs, larvae, pupae have offspring). Keywords: Efficacy, possession and attack of the drill, percentage of infestation, broca cherry trees, Botanical insecticide Keywords: Efficacy, possession and attack of the bit, percentage of infestation, brocade cherry, Botanical insecticide
Comunicación interna en la calidad de la gestión administrativa en las II.EE. del nivel secundaria de la red 09 de Puente Piedra-Lima -2014
Authors: Ibarra Alva Américo , Sánchez Pinedo Doris
Published: October 2020

La investigación científica tiene por título la comunicación interna en la  calidad de la gestión administrativa en las II.EE. del nivel secundaria de la RED 09 de Puente Piedra. La población estuvo conformada por 150 docentes y la muestra es 75 docentes,  el diseño de la investigación es descriptivo, causal correlacional, transversal. Para la recolección de datos se confeccionaron dos cuestionarios estructurados como medición y los instrumentos cumplen con las cualidades de validez y confiabilidad.

En la estructura de investigación comprende el primer capítulo, planteamiento del problema, formulación del problema, los objetivos, la justificación, las hipótesis, la identificación y clasificación de variables. El segundo, presenta antecedentes, base teórica y términos básicos y el tercero, aborda la operacionalización de las variables, tipificación, estrategias, población e instrumentos de recolección de datos. El cuarto, tiene proceso de contratación de hipótesis, presentación, análisis e interpretación de los datos y la prueba de hipótesis y finaliza con las conclusiones, recomendaciones, bibliografía y anexos.

Los resultados obtenidos nos permiten llegar a la siguiente conclusión, de acuerdo a la prueba de Ch2 el resultado de Correlación muestra con un índice de, 0.953, es decir 95.3%, con un índice de libertad de ,047 o 4.7%, con lo que se valida la hipótesis alterna que dice: “La comunicación interna se relaciona con la  calidad de la gestión administrativa en  las II.EE. del nivel secundaria de la RED 09 de Puente Piedra-Lima -2014”.
Uso de los medios audiovisuales y su incidencia en la calidad educativa en el nivel inicial de la institución educativa N°608 Puente Piedra – Lima – Perú – 2011
Authors: Cordero Tocas Lila Filomena , Escalante López María
Published: October 2020

La investigación científica que hemos realizado es básica, correlacional causal no experimental, los factores de estudio son dos: Uso de los medios audiovisuales y la calidad educativa en el Nivel Inicial de la Institución Educativa N° 608 – Puente Piedra – Lima. La  muestra estuvo conformada por 24 docentes del Nivel Inicial de la Institución Educativa N° 608 de Puente Piedra. El diseño de la investigación es transemccional, correlacional, causal. bivariada, transversal. Para la recolección de datos se confeccionaron dos cuestionarios estructurados como medición  y consta de dos aspectos: Uso de los medios audiovisuales y la calidad educativa propiamente dicha.  Los instrumentos cumplen con las cualidades de validez y confiabilidad. El estudio plantea la siguiente hipótesis de investigación: El uso de los medios audiovisuales se relaciona significativamente con la calidad educativa en el Nivel Inicial de la Institución Educativa N° 608 – Puente Piedra – Lima.
El clima organizacional y desempeño docente en la Universidad “Jaime Bausate y Meza” Jesús María - Lima, 2016
Authors: Barriga Rodríguez Rhomao Diego , Pando Ezcurra Tamara
Published: October 2020

El diseño de la investigación es transeccional, correlacional, causal. bivariada, transversal. Para la recolección de datos se confeccionaron dos cuestionarios estructurados como medición  y consta de dos variables: El clima organizacional que tiene las siguientes dimensiones: Talento humano, diseño organizacional y cultura organizacional. La variable desempeño docente comprende las siguientes dimensiones: capacidad pedagógica, responsabilidad de desempeño, relaciones interpersonales y resultados de la labor educativa que se aplicó a los 40 docentes de la muestra.                                       

En los que encontramos que el coeficiente de correlación Rho de Spearman es BUENA de 0,755 y el p_ valor es de 0,001 por lo tanto vemos que existe una relación directa y un nivel de significancia menor que 0,05 motivo por el cual se rechaza la hipótesis Nula y se acepta la hipótesis alterna que sugiere que el clima organizacional se relaciona con la desempeño docente en la Universidad “Jaime Bausate y Meza”. Jesús María. Lima 2016. Validándola.
The generalized Petersson trace formula for congruence subgroups
Authors:   Institute for Applied Mathematics, Far Eastern Branch, Russian Academy of Sciences, Vladivostok, Russia, Avdeeva M.O.
Published: October 2020

In this paper, a generalization of the Petersson trace formula for holomorphic parabolic forms with positive even weight with respect to congruence subgroup \Gamma_0 (N) of the Dirichlet character modulo N is proved
Prototype Gerbang Otomatis Berbasis Mikrokontroler ATMEGA 89S51 Menggunakan GPS Android
Authors: Satria Devit , Wati Lidya
Published: October 2020

Keamanan merupakan salah satu yang paling penting bagi setiap orang yang memiliki rumah di perkotaan. Salah satu cara yang biasa bagi pemilik rumah dalam membuat keamanan adalah dengan membangun gerbang atau pagar. Gerbang atau pagar digunakan untuk membuat suatu tanda batas luar dan dalam pekarangan rumah. Tentunya gerbang dapat ditingkatkan lagi kepraktisannya dengan menambahkan fasilitas kontrol gerbang secara otomatis. Sementara itu, perangkat elektronik seperti smartphone saat ini sudah dilengkapi fitur GPS, sehingga dapat dimanfaatkan dalam berbagai hal contoh nya adalah otomatisasi gerbang atau pagar rumah.

Pada skripsi ini, peneliti mencoba menganalisis pokok-pokok permasalahan yang ada dan mencoba memberikan panduan kepada pemilik rumah untuk dapat menambahkan  kepraktisan pada gerbang atau pagarnya dengan memanfaatkan fitur GPS yang ada di smartphone Android nya.

Hasil dari penelitian ini adalah sebuat alat yang dapat membuka gerbang atau pagar agar dapat bekerja secara otomatis ketika saat menuju ke rumah. Selain itu, smartphone Android juga dapat digunakan untuk membuka dan menutup secara manual.
Pengaruh Beta Pasar, Beta Akuntansi, dan Beta Fundamental terhadap Volatilitas Harga Saham dan Return Saham sebagai Variabel Moderating Pada LQ 45
Authors: . Firmansyah
Published: October 2020

Bagi perusahaan yang sangat membutuhkan pendanaan atau modal dengan segera, salah satu cara untuk mendapatkannnya tentu saja melalui listing ke pasar modal. Dimana pasar modal merupakan tempat  bertemunya investor yang memiliki kelebihan dana dengan investor yang kekurangan dana.   Dana tersebut dapat berupa surat-surat berharga seperti saham, obligasi dan lain sebagainya. Di dalam menanamkan atau menginvestasikan dananya seorang investor selalu melihat kondisi perusahaan yang akan diinvestasikannya, kondisi tersebut dapat berupa kondisi volatilitas harga saham perusahaan atau pergerakan harga saham perusahaan.  Volatilitas harga saham menunjukkan pola perubahan harga saham yang menentukan pola return yang diharapkan dari saham. Pola perilaku saham di pasar modal menjadi perhatian bagi para pelaku pasar untuk menentukan waktu yang tepat dalam berinvestasi. Dari volatilitas harga saham tersebut dapat menghasilkan adanya return saham atau keuntungan saham, keuntungan saham tersebut dapat dipengaruhi oleh adanya resiko. Resiko tersebut dapat di ukur dengan menggunakan beta. Beta dapat terdiri dari beta pasar, beta akuntansi dan beta fundamental.  Objek penelitian yang peneliti pergunakan dalam penelitian ini adalah saham LQ 45 hal yang mendasari peneliti menggunakan saham LQ 45 salah satunya saham LQ 45 merupakan saham yang paling aktif yang di perdagangkan di pasar bursa atau pasar modal. Hasil penelitian adalah beta pasar , beta akuntansi, dividen pay out ratio, asset growth, leverage, liquidity, asset size, earning variability,  dan accounting  beta dengan return  saham memiliki nilai sebesar 37,8%, Besarnya pengaruh beta pasar, dividen pay out ratio, asset growth, leverage, liquidity, asset size, earning variability,  dan accounting  beta dengan return saham yang dilakukan secara gabungan sebesar 61,0%. Dividen payout ratio, asset growth, liquidity, sedangkan pengaruh tidak langsung beta pasar terhadap volatilitas harga saham melalui return saham adalag signifikan, pengaruh dividen payout ratio, beta pasar  terhadap volatilitas harga saham melalui return saham  adalah tidak signifikan, pengaruh asset growth terhadap volatilitas harga saham melalui return  saham adalah tidak signifikan,  leverage terhadap volatilitas harga saham melalui return  saham adalah signifikan, liquidity terhadap volatilitas harga saham melalui return  saham adalah tidak signifikan, dan asset size, earning variability,  dan accounting  beta terhadap volatilitas harga saham melalui return  saham adalah signifikan.
Perancangan Sistem Informasi Pengelolaan Data Warga Binaan Sosial Di UPT. Bina Laras Dinas Sosial Provinsi Riau
Authors: . Bramesta , Wijoyo Hadion
Published: October 2020

Selama ini pengelolaan data warga binaan sosial di UPT. Bina Laras Dinas Sosial Provinsi Riau masih seadanya dan belum menerapkan sistem komputerisasi secara optimal. Data-data yang ada hanya diolah dengan menggunakan Microsoft Word dan Excel, dengan file-file yang berbeda. Hal ini menyebabkan pencarian data menjadi lama dan sulitnya mengelola data-data tersebut. Padahal data yang ada cukup banyak dan saling berkaitan satu sama lain. Dengan adanya masalah tersebut, penulis merasa perlu untuk membuat suatu sistem informasi yang dapat mengelola semua data yang ada di dalam satu program aplikasi. Sistem Informasi Pengelolaan Data Warga Binaan Sosial UPT. Bina Laras Dinas Sosial Provinsi Riau ini dibuat dengan menggunakan bahasa Java dan MySQL sebagai databasenya. Akhirnya dengan adanya sistem informasi ini, dapat mempermudah user dalam mendapatkan informasi yang dibutuhkan dengan cepat, efesien dan efektif. Begitupun dengan update data juga akan menjadi lebih gampang. Pembuatan laporan yang biasanya relatif lama juga akan menjadi lebih cepat.
Pengaruh Pemahaman Wajib Pajak dan Kesadaran Wajib Pajak terhadap Kepatuhan Wajib Pajak dengan Prefensi Resiko sebagai Moderating
Authors: . Masril
Published: October 2020

Pajak merupakan salah satu bagian terpenting dalam APBN dikarenakan pajak dapat bertujuan sebagai modal dalam pembangunan di Indonesia. Khusunya di Indonesia Dalam meningkatkan jumlah penerimaan pajak di Indonesia, pemerintah mencoba melakukan amnesty taxes dengan tujuan agar penerimaan pajak dapat meningkatkan sehingga kepatuhan akan dalam membayar pajak juga meningkat. Salah satu faktor yang dapat mempengaruhi kepatuhan wajib pajak dapat seperti pemahaman wajib pajak tersebut maupun kesadaran akan pajak. Hasil penelitian adalah pemahaman wajib pajak berpengaruh secara langsung terhadap kepatuhan wajib pajak, kesadaran wajib pajak berpengaruh secara langsung terhadap kepatuhan wajib pajak, adanya pengaruh pemahamahan wajib pajak secara tidak langsung terhadap kepatuhan wajib pajak melalui preferensi resiko, dan adanya pengaruh kesadaran wajib pajak secara tidak langsung terhadap kepatuhan wajib pajak melalui preferensi resiko.
Pengaruh Kepemimpinan dan Budaya Kerja terhadap Kinerja Pegawai Pada Kantor Pelayanan Pajak Pratama Jakarta Kelapa Gading
Authors: Meide Carmel
Published: October 2020

Penelitian dilakukan kantor pelayanan pajak pratama jakarta kelapa gading yang bertujuan untuk mengetahui apakah ada hubungan yang signifikan antara Kepemimpinan terhadap Kinerja Pegawai, apakah ada hubungan yang signifikan antara Budaya Kerja terhadap Kinerja Pegawai dan apakah ada pengaruh Kepemimpinan, Budaya Kerja secara simultan terhadap Kinerja serta bagaimana analisis SWOT mengatasi permasalahan kinerja pegawai di KPP Pratama Jakarta Kelapa Gading. Dalam uji parsialnya variabel budaya kerja mempunyai korelasi yang dominan terhadap kinerja di lingkungan Kantor Pelayanan Pajak Pratama Jakarta Kelapa Gading. Variabel budaya kerja ini dapat memberikan sumbangan terbesar dalam mendorong pegawai untuk memiliki hasrat kerja yang tinggi, serta mampu memberikan sumbangan terhadap peningkatan kinerja yang baik.