bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluasi Penerapan Job Order Costing dalam Penentuan Harga Pokok Produksi
Authors: Alfarisi Salman , Boediono Gideon Setyo Budiwitjaksono
Published: October 2023

Penelitian ini merupakan studi kasus pada CV Adi Guna Utama, Mojokerto Jawa Timur. Tujuan penelitian ini untuk mengevaluasi penerapan metode job order costing dalam penentuan harga pokok produksi pada CV Adi Guna Utama. Dalam menganalisis perbedaan pada penerapan metode job order costing yang dilakukan perusahaan dengan teori sistem perhitungan biaya berdasarkan pesanan yang tepat. Penelitian ini menggunakan jenis penelitian kualitatif deskriptif, yaitu penelitian yang memberikan gambaran tentang kejadian-kejadian yang berkaitan dengan penghitungan harga pokok produksi. Dimana penelitian ini melihat efektifitas sejauh mana penerapan job order costing dalam penentuaan harga pokok produksi pada CV. Adi Guna Utama. Dari hasil penelitian ini menjelaskan bahwa cara pembebanan BOP yang dilakukan CV. Adi Guna Utama kurang tepat untuk pesanan kaki meja. Hasil dari penelitian ini menunjukkan bahwa terdapat perbedaan perhitungan harga pokok produksi antara metode perusahaan dengan metode job order costing. Hasil perhitungan dengan metode perusahaan lebih rendah karena pada metode perusahan ada biaya yang belum dimasukkan yaitu biaya pemeliharaan mesin dalam penentuan harga pokok produksi.
Factors Affecting Investment Opportunity Set: A Study of Company Advantages and Limitations
Authors: Sari Permata , Supratiwi Wiwik
Published: October 2023

This study aims to prove the influence of Company advantages - company profitability and size, and company limitations - systematic risk and leverage, on the Investment Opportunity Set (IOS) in automotive companies listed on the Indonesia Stock Exchange during the period 2013 to 2017. There are 5 automotive companies that used as samples based on purposive sampling technique. The results of the study prove that the company's advantages have an effect on IOS, while the company's limitations have no effect on IOS. These results prove that the company must be able to maintain its advantages so that it can have greater growth opportunities. On the other hand, with the lack of evidence of company limitations as a factor affecting IOS, it does not mean that companies are not careful in making financial policies.
Differences in the Financial Performance before and after Revaluation of Fixed Assets
Authors: Yulianto Ricky , Suryaningrum Diah Hari
Published: October 2023

This study aims to determine and test differences in companies' financial performance before and after the revaluation of fixed assets empirically. The data obtained were analyzed using the t-test analysis technique for two related samples (paired-sample t-test). The conclusion of the research results is first, there is no difference in the Debt-to-Equity Ratio, Fixed Assets to Net Worth, and Return on Investment after the implementation of fixed asset revaluation. Before implementing fixed asset revaluation. Second, there is no difference in the company's financial performance before implementing fixed asset revaluation and after the revaluation implementation. These results indicate that while there is an increase in assets' value, the financial performance is not affected. Therefore, the policy for fixed assets revaluation must be implemented carefully. The company must make a strategic decision accompanying the policy so that the assets' revaluation will increase financial performance.
The Influence of Pressure, Opportunity, Rationalization and Ethical Value on the Accounting Fraud Tendency
Authors: Pradipta Adhika , Bernawati Yustrida
Published: October 2023

The purpose of this study is to prove empirically the influence of pressure, opportunity, rationalization, and ethical value on the tendency of fraudulent accounting employees of accounting and finance companies operating in Surabaya. Pressure, opportunity, rationalization, and ethical values ​​are measured by the Likert scale 1-5. The population used includes accounting and financial employees of companies that operate in Surabaya. Determination of sampling using purposive judgmental sampling method and obtained 74 respondents. This study's analysis technique uses a linear regression method with a confidence level of 5% by using SPSS 25.0. This study proves that the variables of pressure, opportunity, and rationalization have a significant positive effect on the accounting fraud tendency. In contrast, the ethical value variable has a significant negative impact on the preference for accounting fraud. The coefficient of determination with the Adjusted R Square value of 41.1% means that the accounting fraud tendency is explained by the variables of pressure, opportunity, rationalization, and ethical values, while other variables explain the rest.
Marketing Audit: Does It Affect Marketing Planning and Marketing Effectiveness in the Sales Function?
Authors: Cahya Ananda Dwi
Published: October 2023

This study aimed to prove the effect of marketing audits on marketing planning and the influence between marketing audits and the marketing effectiveness of the sales function at PT. MSJ Sidoarjo - Indonesia. This study uses primary data from the SPI manager, marketing manager, accounting manager, audit team, and SPI amperage, totaling 26 people, and the sampling amperage used is a census. The analysis technique used is the Analysis of Variance (ANOVA). This study consists of the dependent variable, namely marketing planning, and marketing effectiveness of the sales function, as well as a group (marketing audit) of more than two, namely a "good" marketing audit group, a "good" marketing audit group. And the "bad" marketing audit group. Based on the analysis of variance (ANOVA), it is concluded that marketing audits affect marketing planning. Conversely, marketing audits have no effect on marketing effectiveness in the sales function.
Factors that Influence Corporate Social Responsibility Disclosure
Authors: Rahayu Rika , Hastuti Sri
Published: October 2023

Corporate Social Responsibility (CSR) is a factor that influences the development and survival of a company. This study aims to analyze several factors that influence disclosure of corporate social responsibility (CSR) by managerial ownership testing, institutional ownership, and public share ownership. The population used is a company registered in the IDX30 index of the Indonesia Stock Exchange during the period 2015-2017, which amounted to 40 companies. The sampling technique uses a purposive sampling technique. The samples taken are 39 samples that meet the criteria of purposive sampling. Data is obtained from annual reports and sustainability reports (if any). This study uses a quantitative approach with multiple linear regression analysis. The results of this study indicate that: first, managerial ownership affects the disclosure of corporate social responsibility; second, institutional ownership does not affect the disclosure of corporate social responsibility; and third, public share ownership affects the disclosure of corporate social responsibility. These results implicate that the internal (management) and the external (public) ownership gave pressure to the company to disclose its CSR
The Influence of Knowledge Investment and Gender on Students Interests in stocks Investment with minimal capital as a Moderation Variable
Authors: Suarista Shelsia Yola , Anwar Saiful
Published: October 2023

This study aims to test the effect of investment knowledge and gender on interest investment in capital markets with minimal capital investment as a moderation variable. This research uses a quantitative method with primary data obtained by distributing questionnaires and measured using a Likert scale. The subjects of this study were accounting students at UPN Veteran East Java class of 2016. This study used a proportional random sampling technique. The samples used in this study were 84 respondents. The analysis technique used in this study is Partial Least Square (PLS) using warpPLS 6.0. The results of this study indicate that investment knowledge is influential and gender differences do not affect the interests of stock investment students. Furthermore, minimal capital as a moderating variable strengthens Investment Knowledge towards stock investment student interest. Meanwhile, minimal capital cannot moderate gender to interest in stock investments.
Effect of Profitability, Company Size, and Growth of Sales on Capital Structure
Authors: Suwondo Lolyta Damayanti , Muslimin Muslimin
Published: October 2023

This study aims to determine and empirically test the effect of profitability, company size, and sales growth toward the capital structure. Capital structure is an essential issue for any company due to the good and bad capital structure will have a direct effect on the financial condition of companies. The data in this study are secondary data in the form of financial statements of companies in the consumer goods industry sector listed at IDX and related company sites. The population in this study were 57 companies in the consumer goods industry sector listed at IDX. The sampling technique used in this study is purposive sampling and there were 39 companies used as research samples. The data analysis technique used in this study is multiple linear regression analysis. The data obtained were processed using a computer with SPSS 22 program.  Based on the analysis and hypothesis testing, the results show that profitability and company size have a significant effect on the capital structure of companies in the consumer goods industry sector listed at IDX in the period 2016 – 2018. Meanwhile, sales growth has no significant effect on the capital structure of companies in the consumer goods industry sector listed at IDX for the period 2016 - 2018.
Analysis of the influence of Cross-Strait policy on pineapple trade
Authors: WANG Qingren WANG
Published: October 2023

To prevent the risk of plant epidemic at the source, the General Administration of Customs of mainland China decided to prohibit the import of pineapples from Taiwan starting from March 1, 2021. Leveraging data from the 2020 mainland China and Taiwan Agricultural Statistical Report, we constructed a model to analyze the impact of mainland China's trade policy changes on the pineapple market in Taiwan. The results of the analysis indicate that the policy change will have a severe impact on Taiwan's pineapple market and will significantly affect producers' investment confidence. Achieving market equilibrium and overall efficiency in the pineapple market would be challenging, given the targeted nature of this policy change. Comparatively, the fruit industry, including pineapples, exhibits the weakest durability in risk management against such targeted policy changes, when compared to other agricultural products. Import policies from large unified market economies have a decisive impact on small exporting regions.
Local existence for a viscoelastic Kirchhoff type equation with the dispersive term, internal damping, and logarithmic nonlinearity
Authors: Cordeiro Sebastiao , Raposo Carlos , Ferreira Jorge , Rocha Daniel , Shahrouzi Mohammad
Published: October 2023

This paper concerns a viscoelastic Kirchhoff-type equation with the dispersive term, internal damping, and logarithmic nonlinearity. We prove the local existence of a weak solution via a modified lemma of contraction of the Banach fixed-point theorem. Although the uniqueness of a weak solution is still an open problem, we proved uniqueness locally for specifically suitable exponents. Furthermore, we established a result for local existence without guaranteeing uniqueness, stating a contraction lemma.
Local irregularity conjecture for 2-multigraphs versus cacti
Authors: Grzelec Igor , Wo�niak Mariusz
Published: October 2023

A multigraph is locally irregular if the degrees of the end-vertices of every multiedge are distinct. The locally irregular coloring is an edge coloring of a multigraph \(G\) such that every color induces a locally irregular submultigraph of \(G\). A locally irregular colorable multigraph \(G\) is any multigraph which admits a locally irregular coloring. We denote by \(\textrm{lir}(G)\) the locally irregular chromatic index of a multigraph \(G\), which is the smallest number of colors required in the locally irregular coloring of the locally irregular colorable multigraph \(G\). In case of graphs the definitions are similar. The Local Irregularity Conjecture for 2-multigraphs claims that for every connected graph \(G\), which is not isomorphic to \(K_2\), multigraph \(^2G\) obtained from \(G\) by doubling each edge satisfies \(\textrm{lir}(^2G)\leq 2\). We show this conjecture for cacti. This class of graphs is important for the Local Irregularity Conjecture for 2-multigraphs and the Local Irregularity Conjecture which claims that every locally irregular colorable graph \(G\) satisfies \(\textrm{lir}(G)\leq 3\). At the beginning it has been observed that all not locally irregular colorable graphs are cacti. Recently it has been proved that there is only one cactus which requires 4 colors for a locally irregular coloring and therefore the Local Irregularity Conjecture was disproved.
Uniqueness for a class p-Laplacian problems when a parameter is large
Authors: Alreshidi B. , Hai D.D.
Published: October 2023

We prove uniqueness of positive solutions for the problem \[-\Delta_{p}u=\lambda f(u)\text{ in }\Omega,\ u=0\text{ on }\partial \Omega,\] where \(1\lt p\lt 2\) and \(p\) is close to 2, \(\Omega\) is bounded domain in \(\mathbb{R}^{n}\) with smooth boundary \(\partial \Omega\), \(f:[0,\infty)\rightarrow [0,\infty )\) with \(f(z)\sim z^{\beta }\) at \(\infty\) for some \(\beta \in (0,1)\), and \(\lambda\) is a large parameter. The monotonicity assumption on \(f\) is not required even for \(u\) large.
TOPRAK MESELESİNİN ÇÖZÜMÜNE YÖNELİK BİR ADIM: DÂHİLİYE VEKÂLETİNİN 1937 TARİHLİ TOPRAK KANUNU TASARISI
Authors: DALAN Mustafa Ersagun
Published: October 2023

Yeni kurulan cumhuriyetin, siyasi, iktisadi ve sosyal meselelerde milletin rejimle olan bağlarını güçlendirmek amacıyla bir takım gelişmeler kaydettiği açıktır. İçeriği itibariyle siyasi, sosyal, iktisadi ve kültürel konuları bünyesinde barındıran ‘toprak meselesi’, önemini daha da arttırarak çözülmesi gereken öncelikli meselelerden biri olmuştur. 1930’lu yıllarda çıkarılan kanunlarla meselenin çözümüne yönelik adımlar atılsa da tam bir reformdan bahsetmek mümkün değildir. Dâhiliye, Sıhhat ve İçtimai Muavenet Vekâletleri tarafından hazırlanan toprak reformu tasarıları da muhalefetin ve büyük toprak sahiplerinin tepkisi, yaklaşan II. Dünya Savaşı gibi nedenlerle hayata geçirilememiştir. Bu çalışmada, toprak meselesinin çözümüne yönelik atılan adımlar yeni belgeler ışığında kısaca değerlendirilerek, Dâhiliye Vekâletinin 1937 tarihli toprak kanunu tasarısı incelenecektir.

Çalışmamızda özellikle, Türkiye Cumhuriyeti Cumhurbaşkanlığı Devlet Arşivlerinde bulunan belgelerden istifade edilmiştir. Ayrıca Türkiye Büyük Millet Meclisi zabıt tutanaklarından, süreli yayınlardan, telif ve tetkik eserlerden faydalanılmıştır.
TÜRKİYE CUMHURİYETİ İLE AMERİKA BİRLEŞİK DEVLETLERİ İLİŞKİLERİNDE KRİZ: PANTURANİZM
Authors: KIYANÇ Sinan
Published: October 2023

Bu çalışmada ABD’nin Panturanizm’e bakışı ele alınmaktadır. Osmanlı Devleti’nin son yıllarında dünyadaki Pan hareketlerinin bir yansıması olarak ortaya atılan Panturanizm-Turancılık, Osmanlı Devleti nezdinde kabul görmüştür. Turan ırkının bir araya getirilmesini amaçlayan Panturanizm, İngiltere tarafından Milli Mücadele karşıtlığı için propaganda malzemesi yapılmıştır. ABD’de Türk karşıtlığı üzerinden şekillenen Panturanizm, Ermeni ve Yunan lobilerinin etkisi ile kamuoyunda geniş yer tutmuştur. Milli Mücadele’nin hemen başında Amerikan kamuoyunda Mustafa Kemal Paşa’nın bu olgu üzerinden hareket ettiği iddiaları, Milli Mücadele’ye karşı propaganda faaliyetlerinin ne kadar etkili olduğunu göstermektedir. Milli Mücadele’nin askeri alanın yanı sıra propagandalara karşı da mücadelesinin bir örneği de Panturanizm hakkında yaşananlardır. Cumhuriyetin ilanının hemen başına kadar varlığını koruyan Panturanizm algısı, yeni devletin bu fikirde olmadığı yönünde açıklamaları ile Amerikan kamuoyunda bu konuda yayınlar nedeniyle gündemden düşmüştür.

Çalışmada tarih sınırlandırılmasına gidilerek, Türkiye Cumhuriyeti’nin ilk yıllarına kadar olan kısım ele alınmaktadır. Panturanizm’in Milli Mücadele ve Türkiye Cumhuriyeti aleyhinde nasıl bir propaganda malzemesi olarak kullanıldığı, iki ülke ilişkilerine nasıl etki ettiği ve Mustafa Kemal Paşa’nın bu propagandaya karşı nasıl mücadele ettiği sorularına arşiv kaynakları ve birinci el kaynaklar başta olmak üzere araştırma eserlerinden elde edilen bilgi ve bulgularla cevap verilmektedir. Bir propaganda malzemesi olarak kullanılan ve Amerikan kamuoyunda yer alan Panturanizm’in ülkedeki Türk aleyhtarlığını güçlendiren unsurlardan birisi olduğu bu durumun da iki ülke ilişkilerinde olumsuz bir etkiye neden olduğu savunulmaktadır.
THE PROBLEMS EXPERIENCED BY THE LAST OTTOMAN PARLIAMENTARIANS WHO WERE ABLE TO JOIN THE GRAND NATIONAL ASSEMBLY IN THE FIRST TERM IN TERMS OF REACHING THE PARLIAMENT
Authors: YILMAZ Yakup
Published: October 2023

The defeat of the Ottoman Empire in the First World War and the occupation of the country and its institutions, including Istanbul, by the Allied Powers hampered the work of the Parliament. This parliament, which was the last Ottoman Parliament, was an authority that showed the courage to take decisions that would positively affect the fate of the Turkish nation. So much so that it was able to take the "Misak-ı Milli" decisions, which are still actively used even in today's politics, and declare the indivisibility and unity of the homeland even under occupation.

This parliament was seen as a structure that could not be controlled by the British and it was shut down. Subsequently, the members either fled or were sent into exile. Following this event, Mustafa Kemal and his friends deemed it necessary to open a new parliament in Ankara and this new constituent assembly was able to convene on April 23, 1920. As a result of the elections held, along with the new deputies who joined the assembly, the remaining deputies from the last Ottoman parliament were asked to come to Ankara and join the assembly.

Many patriotic former Ottoman MPs who were able to escape from Istanbul, exile or imprisonment came to Ankara and started to work in the constituent assembly. The processes of their participation in the Grand National Assembly and the problems they faced are tried to be revealed in this study. The aforementioned process has been revealed by using both research works and official sources and memoirs of the period.

Keywords: Ottoman Mebusan Assembly, Grand National Assembly, , Deputy.

This parliament was seen as a structure that could not be controlled by the British and it was shut down. Subsequently, the members either fled or were sent into exile. Following this event, Mustafa Kemal and his friends deemed it necessary to open a new parliament in Ankara and this new constituent assembly was able to convene on April 20, 1920. As a result of the elections held, along with the new deputies who joined the assembly, the remaining deputies from the last Ottoman parliament were asked to come to Ankara and join the assembly.

Many patriotic former Ottoman MPs who were able to escape from Istanbul, exile or imprisonment came to Ankara and started to work in the constituent assembly. The processes of their participation in the First Grand National Assembly and the problems they faced are tried to be revealed in this study. The aforementioned process has been revealed by using both research works and official sources and memoirs of the period.

Keywords: Ottoman Mebusan Assembly, Grand National Assembly, , Deputy,
1923 TÜRKİYE İKTİSAT KONGRESİ’NDE TÜRK KADINI
Authors: BEDİR Ayşe
Published: October 2023

Lozan Konferansı’nın kesintiye uğradığı dönemde, yeni devletin ekonomi politikalarını tartışmak, memleketin ihtiyaçlarına uygun iktisadi politikaları belirlemek ve dünya kamuoyuna tam bağımsız bir Türkiye mesajını vermek üzere 17 Şubat-4 Mart 1923 tarihleri arasında İzmir’de ilk Türkiye İktisat Kongresi toplanmıştır. Bu çalışmanın konusu, İktisat Esaslarımız adlı doküman üzerinden Türk kadınının Türkiye İktisat Kongresi’ndeki yerini araştırmaktır. Çalışmanın amacı, kongre açış ve kapanış konuşmalarında kadının nasıl ve ne şekilde yer aldığını belirlemek, kongrede kadının ne ölçüde temsil edildiğini ve kongre kararları üzerinden yeni Türk Devleti’nde kadının iktisadi hayattaki yerini, iktisadi politikalarda kadına biçilen rolü dolayısıyla da kurucu kadronun düşünce dünyasında kadının yerini tespit etmektir. Araştırma, 1923 tarihli ilk İktisat Kongresi’nde Türk kadını konusuyla sınırlandırılmıştır. Çalışma, tarihsel kritik bir yaklaşımla nitel araştırma yöntemlerinden doküman analizi tekniği kullanılarak yapılmıştır. Bu çalışma, kongrede ve yeni devletin iktisadi hayatında Türk kadının yerini İktisat Esaslarımız üzerinden doküman analizi metoduyla ele alması bakımından alan yazına katkıda bulunmayı hedeflemektedir. Kongre konuşmaları ve kararlarıyla ilgili içerikler, mesleki temsil esasına göre bütün iktisat birimlerini kapsayacak şekilde, cinsiyet ayrımı gözetilmeden, kadın-erkek bütün fertlere hitaben halkçı bir yaklaşımla ele alınmıştır. Yine kurtuluş mücadelesinde hayati rol oynayan Türk kadının, kuruluş mücadelesinde de tam bağımsız bir Türkiye ideali için iktisat savaşında da birlik ve beraberlik ruhu içinde, memleketin iktisadi hayatında da bizzat söz sahibi olacağı araştırmanın öne çıkan bulgularıdır. İktisat Esaslarımız başlıklı ana doküman yanında, konuyla ilgili literatür, dönemin süreli yayınları, resmi yayınlar ve arşiv belgeleri bu çalışmanın kaynakları arasındadır.
Activity of the pleiotropic drug resistance transcription factors Pdr1p and Pdr3p is modulated by binding site flanking sequences
Authors: Buechel Evan R. , Pinkett Heather W.
Published: October 2023

The transcription factors Pdr1p and Pdr3p regulate pleiotropic drug resistance (PDR) in Saccharomyces cerevisiae via the PDR responsive elements (PDREs) to modulate gene expression. However, the exact mechanisms underlying the differences in their regulons remain unclear. Employing genomic occupancy profiling (CUT&RUN), binding assays, and transcription studies, we characterized the differences in sequence specificity between transcription factors. Findings reveal distinct preferences for core PDRE sequences and the flanking sequences for both proteins. While flanking sequences moderately alter DNA binding affinity, they significantly impact Pdr1/3p transcriptional activity. Notably, both proteins demonstrated the ability to bind half sites, showing potential enhancement of transcription from adjacent PDREs. This insight sheds light on ways Pdr1/3p can differentially regulate PDR.
TUBA1A licenses APC/C‐mediated mitotic progression to drive glioblastoma growth by inhibiting PLK3
Authors: Wen Jiaqi , Wang Qiuke , Zhang Wenyi , Wang Weizhang
Published: October 2023

Glioblastoma (GBM) is the most common, aggressive, and chemorefractory primary brain tumor in adults. Identifying novel drug targets is crucial for GBM treatment. Here, we demonstrate that tubulin alpha 1a (TUBA1A) is significantly upregulated in GBM compared to low‐grade gliomas (LGG) and normal tissues. High TUBA1A expression is associated with poor survival in GBM patients. TUBA1A knockdown results in mitotic arrest and reduces tumor growth in mice. TUBA1A interacts with the polo‐like kinase 3 (PLK3) in the cytoplasm to inhibit its activation. This interaction licenses activation of the anaphase‐promoting complex or cyclosome (APC/C) to ensure proper Foxm1‐mediated metaphase‐to‐anaphase transition and mitotic exit. Overall, our findings demonstrate that targeting TUBA1A attenuates GBM cell growth by suppressing mitotic progression in a PLK3‐dependent manner.
A guide to epigenetics in leukaemia stem cells
Authors: Agrawal‐Singh Shuchi , Bagri Jaana , Sakakini Nathalie , Huntly Brian J. P.
Published: October 2023

Leukaemia stem cells (LSCs) are the critical seed for the growth of haematological malignancies, driving the clonal expansion that enables disease initiation, relapse and often resistance. Specifically, they display inherent phenotypic and epigenetic plasticity resulting in complex heterogenic diseases. In this review, we discuss the key principles of deregulation of epigenetic processes that shape this disease evolution. We consider measures to define and quantify clonal heterogeneity, combining information from recent studies assessing mutational, transcriptional and epigenetic landscapes at single cell resolution in myeloid neoplasms (MN). We highlight the importance of integrating epigenetic and genetic information to better understand inter‐ and intra‐patient heterogeneity and discuss how this understanding further informs evolution and progression trajectories and subsequent clinical response in MN. Under this topic, we also discuss efforts to identify mechanisms of resistance, by longitudinal analyses of patient samples. Finally, we highlight how we might target these aberrant epigenetic processes for better therapeutic outcomes and to potentially eradicate LSCs.
Mapping literature reviews on coral health: A review map, critical appraisal and bibliometric analysis
Authors: Burke Samantha , Pottier Patrice , Macartney Erin L. , Drobniak Szymon M. , Lagisz Malgorzata , Ainsworth Tracy , Nakagawa Shinichi
Published: October 2023

The state of coral reefs has been of great concern, as documented in the growing amount of primary literature. These reports on coral health have accumulated, resulting in reviews of the primary studies (i.e. secondary literature). Recently, such reviews have also accumulated, creating an opportunity to review the secondary literature. Second‐order syntheses (reviews of secondary literature) provide an overview of the field, which can be used to guide future research.

Based on our previously published protocol, we compiled peer‐reviewed secondary literature on coral health from Scopus and Web of Science databases. We synthesised 335 secondary literature papers on coral health, 35 of which underwent critical appraisal and 333 of which also underwent bibliometric analysis.

The secondary literature consisted primarily of qualitative reviews (78%). Over 80% of papers stated informing coral conservation as the review's purpose. Climate change (50%) and coral resilience (42%) were the most studied topics, and bioerosion was the least (3.6%). Critically appraised papers scored poorly on Collaboration for Environmental Evidence Synthesis Assessment Tool criteria (studies did not meet standards 55% of the time). The authors of the secondary literature were highly interconnected (with 30% of the authors having more than 15 coauthors within our dataset) and included authors from countries with coral reefs (predominantly in Australia and USA; 79% of papers). The secondary literature on coral health had a median Altmetric score of 5.27.

We have revealed key gaps in coral health topics for further review (e.g. coral range shifts and microbial biodiversity), particularly when considering conservation policy. Incorporating research in policy could be improved through greater research accessibility and continuing to gather public interest in coral reefs. We further recommend broadening research collaborations to include even more researchers from countries with coral reefs (e.g. Maldives). Finally, the secondary literature on coral health needs better reporting transparency (e.g. publishing code).

Our second‐order synthesis is timely, pushing coral health research in a new direction—one which produces research of higher quality, collaboration, and efficiency. As coral reefs decline, we should also aim to rebuild public trust in research and strengthen the evidence base for conservation.
Reducing drinking: A harm reduction goal for AUD
Authors: Knopf Alison
Published: October 2023

If anyone wants to know how to define harm reduction for alcohol use disorder (AUD), go no farther than the late, great G. Alan Marlatt, who defined it in 2010.
Hand and finger, ultrasound‐guided, percutaneous core needle biopsies: A safe procedure with high diagnostic accuracy
Authors: Magoon Stephanie , Peters Vanessa , de Souza Felipe Ferreira , Chen David , Owens Patrick , Pretell‐Mazzini Juan , Fullerton Natalia , Jose Jean , Rosenberg Andrew , Subhawong Ty K.
Published: October 2023

Introduction/Purpose

To determine the diagnostic accuracy and complication rates of ultrasound‐guided, percutaneous core needle biopsies of soft tissue masses in the hand and fingers.

Methods

Reports from all ultrasound‐guided procedures between 21 May 2014 and 17 March 2022 were queried for keywords including “hand”, OR “finger”, AND “biopsy”. Patient demographics, lesion size and location, biopsy needle gauge and the number of cores obtained were recorded. The final pathology of the mass excision was then compared with the core needle biopsy (CNB) for each patient.

Results

Sixty‐six records were reviewed, and 37 patients met inclusion criteria. Maximum lesion diameter averaged 1.45 cm with a range between 0.4 and 4.3 cm. The frequency of needle gauges used was 14G (14%), 16G (24%), 18G (38%), 20G (11%) and ‘not reported’ (14%). The mean number of tissue cores obtained was 2.9 (SD 1.2; range 1 to 6), excluding nine cases that reported ‘multiple’. The frequency of CNB diagnoses included tenosynovial giant cell tumour (TGCT) at 30%, ganglion cyst at 11% and epidermal inclusion cyst at 5%. CNB was 100% sensitive in detecting the three (8%) malignancies. Of the 37 tumours biopsied, 16 were surgically excised. One angiomyoma was originally diagnosed as a haemangioma on CNB, but all other histologic results were concordant for a diagnostic accuracy of 97%.

Discussion

Small soft tissue masses in the hands and fingers, even those less than 1 cm, are often amenable to ultrasound‐guided CNB. Performance under image guidance facilitates retrieval of core specimens adquate for histologic diagnosis with relatively few passes using higher gauge needles.

Conclusion

Overall, ultrasound‐guided CNB of the hand and fingers is safe and highly accurate in diagnosing soft tissue tumours. The accuracy is unrelated to the needle's gauge, the number of passes and the size of the lesions.
Dominant Role of Hole Transport Pathway in Achieving Record High Photoconductivity in Two‐Dimensional Metal–Organic Frameworks
Authors: Wang Denan , Ostresh Sarah , Streater Daniel , He Peilei , Nyakuchena James , Ma Qiushi , Zhang Xiaoyi , Neu Jens , Brudvig Gary W. , Huang Jier
Published: October 2023

Metal–organic frameworks (MOFs) with mobile charges have attracted significant attention due to their potential applications in photoelectric devices, chemical resistance sensors, and catalysis. However, fundamental understanding of the charge transport pathway within the framework and the key properties that determine the performance of conductive MOFs in photoelectric devices remain underexplored. Herein, we report the mechanisms of photoinduced charge transport and electron dynamics in the conductive 2D M−HHTP (M=Cu, Zn or Cu/Zn mixed; HHTP=2,3,6,7,10,11‐hexahydroxytriphenylene) MOFs and their correlation with photoconductivity using the combination of time‐resolved terahertz spectroscopy, optical transient absorption spectroscopy, X‐ray transient absorption spectroscopy, and density functional theory (DFT) calculations. We identify the through‐space hole transport mechanism through the interlayer sheet π–π interaction, where photoinduced hole state resides in HHTP ligand and electronic state is localized at the metal center. Moreover, the photoconductivity of the Cu−HHTP MOF is found to be 65.5 S m−1, which represents the record high photoconductivity for porous MOF materials based on catecholate ligands.
Clonazepam‐related sexual dysfunction in male veterans with PTSD
Authors: Fossey Mark D. , Hamner Mark B.
Published: October 2023

Medication‐induced sexual dysfunction can significantly interfere with patients' quality of life and lead to poor compliance. This retrospective study examined the records of 100 male veterans with post‐traumatic stress disorder (PTSD) selected in alphabetical order from an active treatment file of 230 patients. Forty‐two patients had received clonazepam (mean maximum dose: 3.4 ±1.6 mg/day) at some point during their treatment. Of these, 18 (42.9%) complained of significant sexual dysfunction (primarily erectile dysfunction). Eighty‐four patients received diazepam (mean maximum dose: 52.1 ± 29.7 mg/day), nine received alprazolam (mean maximum dose: 5.2 ± 2.8 mg/day) and eight received lorazepam (mean maximum dose: 3.8 ± 2.4 mg/day). None of these patients complained of sexual dysfunction during treatment with these three other benzodiazepines. Our findings suggest that benzodiazepines, particularly clonazepam in the current study, can be a cause of sexual dysfunction in many male patients. Prospective studies comparing the overall clinical utility of various benzodiazepines are indicated in this and other clinic populations. Anxiety 1:233–236 (1994/1995). © 1995 Wiky‐Liss, Inc.
Preference for quicker offers: The critical roles of temporal reference points and evaluation mode
Authors: Lei Chao , Zhang Pengcheng , Gregory Lance , Wang Haijiang , Wang Guoxuan , Häubl Gerald
Published: October 2023

People may use the amount of time it takes someone else to reach a particular decision as input that informs their thoughts and feelings about that decision. Building on prior work suggesting that people are more inclined to accept offers that are extended more rapidly, the current research shows that this preference for quicker offers depends critically on whether offers are considered simultaneously along with other offers or individually (i.e., joint vs. separate evaluation mode), as well as on the presence and nature of explicit temporal reference points in joint evaluation mode. We theorize that the preference for quicker offers is limited to settings where (1) multiple offers are considered simultaneously and (2) the amount of time it took for these offers to be made exceeds a salient temporal reference point. This implies that the effect should not be observed when multiple offers are considered that were not all generated more slowly than an explicit temporal reference point, or when offers are considered one at a time. Evidence from seven studies provides support for this theorizing. The findings advance our understanding of the nuanced ways in which the amount of time taken to extend offers affects how people interpret, draw inferences from, and respond to these offers.
Electrolytic construction of nanosphere‐assembled protective layer toward stable lithium metal anode
Authors: Lu Gongxun , Li Shuai , Yue Ke , Yuan Huadong , Luo Jianmin , Liu Yujing , Wang Yao , Tao Xinyong , Nai Jianwei
Published: October 2023

The uncontrolled dendrite growth and electrolyte consumption in lithium metal batteries result from a heterogeneous and unstable solid electrolyte interphase (SEI). Here, a high‐voltage forced electrolysis strategy is proposed to stabilize the lithium metal via electrodepositing a spherical protective layer. This peculiar SEI is composed of a nanosized Li sphere that is encased with adjustable composition, as proved by cryo‐transmission electron microscopy and multiple surface‐sensitive spectroscopies. Such a three‐dimensional nanosphere‐assembled protective layer has homogeneous components, mechanical strength, and rapid Li‐ion conductivity, enabling it to alleviate the volume expansion and prevent dendrite growth during Li deposition. The symmetric cell can be stably operated for ultralong‐term cycling time of 2000 and 800 h even at high current densities of 1 and 10 mA cm−2, respectively. Using this interface permits stable cycling of full cells paired with LiFePO4 and LiNi0.8Co0.1Mn0.1O2 cathodes with low negative/positive capacity ratio, high current density, and limited Li excess. This tactic also fosters a novel insight into interface design in the battery community and encourages the practical implementation of lithium metal batteries.
Improvement of drug‐induced gingival overgrowth and cerebrovascular related dementia after dental treatments
Authors: Tanoue Naomi , Kawasaki Hanako , Kiriishi Kensuke , Ayuse Takao
Published: October 2023

Key Clinical Message

Drug‐induced gingival overgrowth can occur as a side effect of specific drugs and lead to poor oral function. Appropriate dental management of the overgrowth may improve oral function and improve cognitive deficits after cerebrovascular accidents.
WO3‐based Materials for Photocatalytic and Photoelectrocatalytic Selective Oxidation Reactions
Authors: Wang Ziru , Einaga Hisahiro
Published: October 2023

Selective oxidation reactions are crucial in producing various chemicals in the industry. However, most catalytic processes for these reactions use harsh reaction conditions. Recently, heterogeneous photo(electro)catalysis has been considered promising for selective oxidation reactions under mild conditions. Semiconductor materials are frequently used as heterogeneous photocatalysts because they can produce active species that contribute to the oxidation of organic compounds under light irradiation. Among various semiconductor photocatalysts, tungsten oxide (WO3) is one of the most promising candidates due to its advantages, including high stability, wide light adsorption range, proper band structures, and unique catalytic mechanism. This paper reviews the WO3‐based materials for photocatalytic (PC) and photoelectrocatalytic (PEC) selective oxidations. We summarize the strategies for designing WO3 structures, which include morphology control, crystal facet optimization, and defect engineering. Then, the finely designed WO3 structures for PC and PEC oxidation of several typical organic compounds have been discussed based on catalytic mechanism and performance. Finally, we propose the prospects and challenges of WO3 photocatalysts and photoanodes in selective oxidation reactions.
Tailoring Secondary Coordination Sphere Effects in Single‐metal‐site Catalysts by Surface Immobilization of Supramolecular Cages
Authors: Laan Petrus C. M. , Bobylev Eduard O. , de Zwart Felix J. , Vleer Joppe A. , Troglia Alessandro , Bliem Roland , Rothenberg Gadi , Reek Joost N. H. , Yan Ning
Published: October 2023

Controlling the coordination sphere of heterogeneous single‐metal‐site catalysts is a powerful strategy for fine‐tuning their catalytic properties but is fairly difficult to achieve. To address this problem, we immobilized supramolecular cages where the primary‐ and secondary coordination sphere are controlled by ligand design. The kinetics of these catalysts were studied in a model reaction, the hydrolysis of ammonia borane, over a temperature range using fast and precise online measurements generating high‐precision Arrhenius plots. The results show how catalytic properties can be enhanced by placing a well‐defined reaction pocket around the active site. Our fine‐tuning yielded a catalyst with such performance that the reaction kinetics are diffusion‐controlled rather than chemically controlled.
Photoisomerization of “Partially Embedded Dihydropyridazine” with a Helical Structure
Authors: Usui Kazuteru , Amano Ami , Murayama Kasumi , Sasaya Miho , Kusumoto Ryota , Umeno Tomohiro , Murase Satsuki , Iizuka Naoko , Matsumoto Shota , Fuchi Yasufumi , Takahashi Kazuyuki , Kawahata Masatoshi , Kobori Yasuhiro , Karasawa Satoru
Published: October 2023

Invited for the cover of this issue are the groups of Kazuteru Usui and Satoru Karasawa at Showa Pharmaceutical University and Yasuhiro Kobori of Kobe University. The image depicts chirality control of helical compounds through cycles of photocleavage and recombination under sunlight with a “Jack and the Beanstalk” motif. Read the full text of the article at 10.1002/chem.202302413.
Electronic Effects in Phosphino‐Iminophosphorane PdII Complexes upon Varying the N Substituent
Authors: Popovici Ingrid , Lognon Elise , Casaretto Nicolas , Monari Antonio , Auffrant Audrey
Published: October 2023

Three series of palladium(II) complexes supported by a phosphine‐iminophosphorane ligand built upon an ortho‐phenylene core were investigated to study the influence of the iminophosphorane N substituent. Cis‐dichloride palladium(II) complexes 1 in which the N atom bears an isopropyl (iPr, 1 a), a phenyl (Ph, 1 b), a trimethylsilyl (TMS, 1 c) group or an H atom (1 d) were synthesized in high yield. They were characterized by NMR, IR spectroscopy, HR‐mass spectrometry, elemental analysis, and X‐ray diffraction. A substantial bond length difference between the Pd−Cl bonds was observed in 1. Complexes 1 a–d were converted into [Pd(LR)Cl(CNtBu)](OTf)] 2 a–d whose isocyanide is located trans to the iminophosphorane. The corresponding dicationic complexes [Pd(LR)(CNtBu)2](OTf)2 3 a–d were also synthesized, however they exhibited lower stability in solution than 2, the isopropyl derivative 3 a being the most stable of the series. Molecular modeling was performed to rationalize the regioselectivity of the substitution of the single chloride by isocyanide (from 1 to 2) and to study the electronic distribution in the complexes. In particular differences between the TMS and H containing complexes vs. the iPr and Ph ones were found. This suggests that the nature of the N substituent is far from innocent and can help tune the reactivity of iminophosphorane complexes.
Cybersecurity and process safety synergy: An analytical exploration of cyberattack‐induced incidents
Authors: Wen He , Khan Faisal
Published: October 2023

In recent years, cyber‐connected industrial control systems (ICS) for remote operations have increased cyber and process risks. While process safety is widely studied, its connectivity with the cyber threat has not been well explored. It is crucial to study cybersecurity and process safety in an integrated way to ensure safe operations. This study addresses this gap by first analyzing the cyber incidents related to ICS since 1990. Subsequently, it connects cyber incidents with process accidents by Bowtie based on the ATT&CK framework. It further develops a Bayesian network due to the insignificant probabilities by Bowtie. The developed model is explained with case analysis. This study confirms that the process industry is prone to cyberattacks, and the field controllers are the main targets of attacks. The study observes that the safety instrument system (SIS) is critical for both the attackers and neutralizing the attacks (defenders). Moreover, attackers deploy newer approaches to attack the ICS, and therefore, methods of threat assessment and its neutralizing strategies should be dynamic.
(R)‐PFI‐2 Analogues as Substrates and Inhibitors of Histone Lysine Methyltransferase SETD7
Authors: Porzberg Miriam R. B. , Lenstra Danny C. , Damen Eddy , Blaauw Richard H. , Rutjes Floris P. J. T. , Wegert Anita , Mecinović Jasmin
Published: October 2023

(R)‐PFI‐2 is a histone substrate‐competitive inhibitor of the human histone lysine monomethyltransferase SETD7. Aimed at developing potent inhibitors of SETD7 that can also act as small molecule substrates, we replaced the pyrrolidine ring of (R)‐PFI‐2 with several side chains bearing nucleophilic functional groups. We explored the inhibitory activity of 20 novel (R)‐PFI‐2 analogues, and found that the most potent analogue has a hydroxyethyl side chain (7). SETD7’s ability to catalyse methylation of (R)‐PFI‐2‐based small molecules was evaluated by mass spectrometric assays, and we observed efficient methylation of analogues bearing lysine mimicking nucleophilic amines. The optimal side chain was found to be an aminoethyl group (1), which was surprisingly also dimethylated by SETD7. The work demonstrates that small molecules can act as both substrates and inhibitors of biomedically important SETD7.
Development and evaluation of the “Toothbrushing Timer with Information on Toothbrushes” application: A prospective cohort pilot study
Authors: Kaneyasu Yoshino , Shigeishi Hideo , Sugiyama Masaru , Ohta Kouji
Published: October 2023

Objectives

For people, it is challenging to be conscious of the appropriate toothbrushing time to maintain good oral health in daily life. The aim of this study was to preliminarily examine the utility of an application (app) that combines a toothbrushing timer and information on toothbrushes.

Materials and Methods

We developed the “Toothbrushing Timer with Information on Toothbrushes” app to help users ensure appropriate toothbrushing time and learn about the beneficial characteristics of toothbrushes. A total of 18 participants were registered for the study. At baseline (T0) and after 1 month (T1) of app usage, study participants answered a digital questionnaire that comprised three questions on oral health practice, self‐efficacy in oral hygiene, and quality of life related to oral health (Oral Health Impact Profile‐14 [OHIP‐14]).

Results

Five participants were excluded from the analysis as they did not answer the digital questionnaire. Finally, 13 participants completed the survey with a follow‐up of 1 month. The 13 participants were grouped into health professionals (n = 8) and non‐health professionals (n = 5). The total scores for oral health practice and self‐efficacy related to oral hygiene increased after a month of app usage in health professional and non‐health professional groups. However, there were no significant differences between T0 and T1 in either group. The total score of OHIP‐14 was lower at T1 than at T0 in both groups. Therefore, participants showed better oral health practice, self‐efficacy in oral hygiene, and quality of life related to oral health at T1 compared with that at T0.

Conclusions

Our app showed positive results for the users and is useful in maintaining and promoting oral health awareness and practice. However, our pilot study lacks sufficient power and did not yield significant differences. Therefore, high‐quality clinical trials with larger sample sizes are warranted for further improvement and evaluation.
Prospective Life Cycle Assessment of Chemical Electrolyte Recycling for Vanadium Flow Batteries: A Comprehensive Study
Authors: Blume Nick , Zielinski Oliver , Becker Maik , Minke Christine
Published: October 2023

Battery storage systems are an important key element for a successful energy transition. Increasingly, the focus is also on the sustainability analysis of the various energy storage technologies. In particular, the vanadium flow battery (VFB) is mentioned as a promising day storage technology. Nevertheless, its high cost and environmental impacts are attributed to its electrolyte. It is assumed that this issue can be addressed through reprocessing and reuse. The aim of this study is to provide, for the first time in the literature, information on the process design and the potential emissions of the treatment of end‐of‐life (EoL) vanadium electrolyte with various critical impurities, in order to be able to validly estimate the total emissions of VFB with recycled electrolyte. Four different scenarios are considered, combining treatment steps for electrolyte with different critical contaminations, revealing detailed mass and energy balances. The life cycle assessment provides valuable results for the sustainability assessment of the EoL vanadium electrolyte and the entire VFB system. The treatment of the electrolyte leads to significantly lower CO2 emissions (−79.2% to −99.8%) compared to the primary electrolyte and must be taken into account in future when assessing the sustainability of the VFB.