bluuebunny/crossref_metadata_2025 huggingface dataset:
RESISTÊNCIA A BETALACTÂMICOS: UMA REVISÃO SISTEMÁTICA DOS MECANISMOS E IMPLICAÇÕES CLÍNICAS
Authors: Souza Gabriel Da Silva De , Sena Geovana Monike Pacheco De , Sousa Jayanne De Lima , Carvalho Amanda Bezerra , Carmona Fábio Maués
Published: November 2024

Introduction: Beta-lactam antibiotics are commonly administered drugs for the treatment of bacterial infections. They act as inhibitors of bacterial cell wall synthesis, which is essential for the bacteria's survival. Bacterial resistance, especially to the class of β-lactam antibiotics, is a growing public health problem that impacts the efficacy of treatments and increases hospital costs. Objective: This work aims to conduct a systematic review on beta-lactam resistance, addressing its mechanisms and clinical implications. Methods: A systematic review was conducted following PRISMA criteria, selecting 15 complete articles published between 2014 and 2024, obtained from the BVS and MedLine databases. The articles were critically analyzed, and relevant data were organized into tables to discuss antibiotic resistance to β-lactams and address its causes, mechanisms, and clinical implications. Results: The reviewed studies indicated that bacterial resistance is influenced by genetic factors and interactions with the intestinal microbiota, in addition to the inappropriate use of antibiotics. Innovative interventions are necessary to address resistance, focusing on specific strains and mechanisms of action. Conclusion: Bacterial resistance requires a multifaceted approach, including an understanding of the mechanisms involved and the implementation of new treatment strategies. The research highlights the importance of effective interventions to combat resistant infections and improve clinical outcomes.
VIOLÊNCIA OBSTÉTRICA SOFRIDA POR MULHERES EM SITUAÇÃO DE PERDA FETAL: UM RELATO DE EXPERIÊNCIA
Authors: Ribeiro Alesy dos Santos , Magalhães Alice Santos , Silva Cibelly Cristine Maia da , Moura Otávio Henrique Santana , Nascimento Raiziliane Araujo do , Santos Lorena Alves , Oliveira Adriano dos Santos
Published: November 2024

O presente estudo tem como objetivo relatar a experiência de violência obstétrica sofrida por mulheres em situação de perda fetal, observada por estudantes de enfermagem durante estágio supervisionado em uma maternidade pública em Manaus, Amazonas. A pesquisa foi motivada pela carência de abordagens humanizadas na assistência obstétrica, especialmente em situações de perda gestacional, e pela recorrência de práticas violentas e negligentes que agravam o sofrimento emocional dessas mulheres. O estudo utilizou o método descritivo, do tipo relato de experiência, no qual os acadêmicos documentaram práticas de violência obstétrica, como negligência no manejo da indução ao parto e falta de apoio emocional. Os resultados demonstram a prevalência de práticas assistenciais tecnocráticas e desumanizadas, com destaque para a ausência de médicos em momentos cruciais, falhas na administração de medicamentos e inadequação na estrutura hospitalar para mulheres em luto perinatal. Conclui- se que há uma urgente necessidade de reformulação na formação dos profissionais de saúde, especialmente na enfermagem obstétrica, para que esses profissionais possam oferecer um atendimento mais humanizado e alinhado às evidências científicas. Além disso, recomenda-se a criação de políticas institucionais que priorizem o acolhimento emocional e o respeito à autonomia das mulheres em situação de perda fetal, prevenindo a perpetuação da violência obstétrica
VANTAGENS DO TRATAMENTO E DIAGNÓSTICO PRECOCE DO CÂNCER DE MAMA EM HOMENS
Authors: Alves Jamin da Silva , Souza Maria Carolina Araújo de , Trelha Laryssa Lima
Published: November 2024

Este estudo tem como objetivo identificar as vantagens do tratamento e diagnóstico precoce do câncer de mama em homens, a fim de propor estratégias eficazes para a prevenção e redução da mortalidade associada à patologia. O estudo baseia-se em uma revisão da literatura e em materiais bibliográficos, documentais e dados disponíveis em plataformas como o Instituto Nacional do Câncer, Google Acadêmico, Biblioteca Virtual da Saúde (BVS) e LinkNovate. A pesquisa será de abordagem mista, com análise quali-quantitativa de dados já existentes, incluindo a construção de tabelas comparativas detalhadas sobre óbitos relacionados ao câncer de mama masculino. Será dada ênfase à classificação das estratégias eficazes utilizadas nos estudos selecionados, bem como à análise quantitativa dos óbitos divulgados por plataformas do Governo Federal e do Ministério da Saúde. Os resultados esperados incluem a identificação de medidas preventivas e estratégias de enfermagem que contribuam para a diminuição da incidência e mortalidade dessa condição em homens. As conclusões deverão corroborar com a importância do diagnóstico precoce e do desenvolvimento de políticas públicas que promovam a conscientização sobre o câncer de mama no sexo masculino.
Sport psychology from a comprehensive PCP point of view
Authors: Del Rizzo Francesca
Published: November 2024

The range of convenience of PCP (Kelly, 1991) has proved to be quite large, and one of the fields in which it can fully prove its usefulness is sport psychology. In the past, thanks in particular to the contributions of Richard Butler (1997; 2000) and David Savage (1999; 2003), we had important examples of the way in which PCP tools can help understand and facilitate athletes’ and coaches’ experiences. In this paper I will try to look at sportspersons’ experience through the lenses of PCP and in particular of the Sociality Corollary. In the first part I will outline my tentative effort to subsume athletic experience by means of PCP professional constructs. In the second part I will illustrate my constructivist approach by means of a case study.
Behavioral Biases in Financial Decision Making : Implications for Accounting and Economic Forecasting
Authors: Jean-Philippe Bonardi  , Didier Sornette  , Robert Danon
Published: November 2024

Behavioral economics has highlighted how cognitive biases influence financial decisionmaking, often leading to suboptimal outcomes. This paper explores the impact of behavioral biases such as overconfidence, loss aversion, and herding behavior on accounting and economic forecasting. By reviewing empirical evidence from market behavior, the study assesses how these biases affect financial reporting, auditing practices, and economic predictions. The paper concludes with recommendations for accountants and economists to incorporate behavioral insights into their practices to improve decisionmaking and forecasting accuracy.
Use The Enterprise Resource Planning System To Support The Implementation Of Cost Rationalization and Achieve Effective Management Applied Research In Wasit Textile and Knitting Factory
Authors: Maytham Abbas Khudhair Al-Salmawi  , Ali Hussein Mahoush
Published: November 2024

Technology has become one of the important pillars on which organizations that want to succeed in their work depend, as well as those that seek to achieve a leading competitive advantage in their field of work. As they develop, institutions face decisions that require correct information, and the appropriate time for decision-making aims to analyze costs and explain the mechanisms used in the industrial sector in Iraq and the impact of implementing the enterprise resource planning system on the economy. And to display unit costs. Therefore, the complexity of business requires complex information systems that help make good management decisions effectively and efficiently and have a positive impact on financial and non-financial systems.
Accounting Theory and Its Effective Role in Developing Intellectual and Mental Skills and Abilities Of Accounting Department Students: a Field Study
Authors: Sadiq Jafar Kathim  , Layla Naji Majeed Al Fatlaw  , Qasim Mohammed Abdullah Al-Baaj
Published: November 2024

The research aims to shed light on the role of accounting theory as one of the main subjects that have an active role in the intellectual skills and abilities of the students of the Department of Accounting and to provide a theoretical framework linking the subject of accounting theory and the intellectual skills and abilities of the students of the Department of Accounting and to indicate the relationship of correlation and influence between the subject of accounting theory and the intellectual skills and abilities of students of the Department of Accounting, and to provide recommendations and proposals to the organisation of the research sample regarding the subject of teaching accounting theory and its active role in the intellectual skills and abilities of students of the Department Accounting, the deductive and inductive approach was adopted in dealing with the research problem and proving its hypotheses in the theoretical aspect to achieve the objectives of the research and relying on the descriptive approach in the practical aspect, The research sample was represented by the students of the Department of Accounting at the College of Administration and Economics - University of Al-Qadisiyah for the year 2024, a questionnaire form was designed and distributed to the research sample and then collected and analysed statistically for the purpose of proving the research hypotheses and achieving the results The research reached a set of conclusions, the most important of which is the information that there is a statistically significant correlation between accounting theory and the intellectual skills and abilities of students of the accounting department The strength of the correlation is characterised by being very strong and its value is (.636**), which is at a lower moral level From (0.01), which confirms the positive correlation of this research, the existence of a significant effect between the variables of the research and the value of the regression coefficient was (β) (.636), which confirms the positive impact of this research, and therefore the study recommends a set of recommendations, the most important of which is the development of the accounting theory approach adopted in the accounting department so that it is able to keep pace with the continuous development known by the reality of the profession, which enables the accountant to perform his tasks better and understand how to teach accounting theory in decision-making processes.
The Effect of Debt Default, Audit Tenure and Liquidity on Going Concern Audit Opinion Acceptance
Authors: Novia Dian Anggraini  , Netty Herawty  , Rico Wijaya
Published: November 2024

This study aims to find out how Debt Default, Audit Tenure and Liquidity can affect the acceptance of the Going Concern Audit Opinion (Empirical Study on Manufacturing Companies in Various Industrial Sectors listed on the IDX for the 2019-2022 period). The sample in this study is Manufacturing Companies in the Various Industrial Sectors using the Purposive Sampling technique so that 26 companies with 4 years of observation (104 observation data) were obtained that met the criteria. The data used is in the form of secondary data obtained from the company's annual report through the Indonesia Stock Exchange (IDX) website and the official website of the related company. Researchers use a quantitative approach to describe research problems through trend descriptions or being able to explain the relationship between variables. The analysis technique used in this study is data analysis using descriptive statistical analysis and logistic regression analysis with the help of SPSS 30 software.  The method of data collection is by means of documentation and literature study. The results of the study concluded that Debt Default significantly affected the acceptance of going concern audit opinions, while Tenure and Liquidity Audit did not significantly affect the acceptance of going concern audit opinions.
The Impact of Project-Based Teaching on Technological Development and Critical Thinking Skills in Higher Education Students
Authors: Gustavo Ramírez García  , Gabriela Elizabeth Rojas Munive De Huali  , Merino Narváez Welinton Cristóbal  , Byron Rubén Vega Moreno
Published: November 2024

Project-based teaching (PBE) has emerged as an effective pedagogical strategy for the development of key skills in higher education, especially in areas such as critical thinking and technological competencies. This study analyzes the impact of EBP on the development of these skills in university students of technological careers. Through a mixed methodology that includes surveys and analysis of academic results, the progress of 120 students was evaluated before and after participating in a project-based course. The findings suggest that EBP not only significantly improves critical thinking skills, but also encourages a more efficient and creative use of technological tools.
EQUAL AI: A Framework for Enhancing Equity, Quality, Understanding and Accessibility in Liberal Arts through AI for Multilingual Learners
Authors: Davoodi Amin
Published: November 2024

The integration of artificial intelligence (AI) into liberal arts education offers a transformative opportunity to address the diverse needs of multilingual and multicultural learners. Consequently, this study introduces the EQUAL AI framework (Enhancing Equity, Quality, Understanding, and Accessibility in Liberal Arts through AI), a structured approach to utilizing AI to foster inclusion and innovation in liberal arts pedagogy. The framework identifies five key domains: linguistic support, cultural representation, creative expression, critical thinking, and collaborative learning. Additionally, the study underscores the necessity of systemic support, particularly through professional development programs that equip educators with technical proficiency, ethical awareness, and the ability to critically assess AI tools. By tackling challenges such as algorithmic bias, data privacy, and the digital divide, the study advocates for culturally responsive policies and inclusive practices. The EQUAL AI framework envisions liberal arts education as a space for equitable participation and cultural understanding, positioning AI as a tool to enhance rather than replace humanistic pedagogy, ensuring its relevance in a technology-driven, interconnected world.
PERANCANGAN DAN IMPLEMETASI SISTEM KONTROL SEPEDA MOTOR BERBASIS SIDIK JARI DAN MOBILE UNTUK KEAMANAN KENDARAAN
Authors: Wadi Hamzan , Suryadi Emi , Akbar Ardiyallah , Samsumar Lalu Delsi
Published: November 2024

Angka pencurian kendaraan bermotor yang tinggi menuntut sistem keamanan yang lebih canggih. Penelitian ini merancang sistem kontrol sepeda motor berbasis sidik jari dan aplikasi mobile untuk meningkatkan keamanan kendaraan. Masalah yang diangkat adalah kelemahan sistem konvensional berbasis kunci fisik yang rentan hilang atau dicuri. Tujuan penelitian ini adalah mengembangkan sistem yang hanya bisa diakses oleh pemilik sah melalui sensor sidik jari dan aplikasi Blynk. Metode penelitian yang digunakan adalah prototipe dengan pendekatan kualitatif untuk memahami kebutuhan pengguna dan menguji efektivitas sistem keamanan. Alat utama yang digunakan mencakup NodeMCU ESP32, sensor sidik jari AS608, dan aplikasi Blynk, dengan tahapan penelitian meliputi perancangan, pengujian, dan evaluasi sistem. Hasil penelitian menunjukkan bahwa sistem berhasil mendeteksi dan memvalidasi sidik jari serta merespons perintah dari aplikasi untuk mengaktifkan dan mematikan sepeda motor. Integrasi sensor sidik jari dan aplikasi mobile ini terbukti meningkatkan keamanan, mencegah akses dari pihak tidak berwenang, serta memungkinkan kontrol jarak jauh dan pengawasan langsung. Sistem ini memberikan solusi keamanan efektif dan efisien bagi pemilik sepeda motor di era digital.
PERANCANGAN DAN IMPLEMENTASI APLIKASI UNTUK MENGKLASIFIKASI PROSEDUR MEDIS BERDASARKAN DIAGNOSIS MEDIS MENGGUNAKAN MACHINE LEARNING
Authors: Andika Fadilla Muhammad , Sutabri Tata
Published: November 2024

Penelitian ini bertujuan untuk mengembangkan sistem klasifikasi prosedur medis otomatis berbasis machine learning yang dapat mengklasifikasikan diagnosis medis ke dalam kode ICD-10 dan ICD-9CM. Sistem dikembangkan menggunakan pendekatan Sentence Transformers dengan model "paraphrase-multilingual-mpnet-base-v2" untuk menangani kompleksitas bahasa medis dan variasi terminologi. Dataset yang digunakan berasal dari platform Satu Sehat yang mencakup lebih dari 140.000 kode diagnosis dan prosedur medis. Hasil pengujian menunjukkan bahwa model mencapai rata-rata tingkat confidence 80.42% dengan standar deviasi 12.58%. Sistem berhasil mencapai akurasi 100% untuk diagnosis standar, 93.3% untuk diagnosis kompleks, dan 87.5% untuk kasus khusus. Kemampuan multilingual sistem terbukti efektif dengan tingkat keberhasilan 94.4% untuk Bahasa Indonesia, 92.9% untuk Bahasa Inggris, dan 100% untuk terminologi medis standar. Validasi menggunakan k-fold cross validation menunjukkan konsistensi performa dengan rata-rata metrics across folds mencapai 80.64%. Hasil penelitian menunjukkan bahwa sistem yang dikembangkan berhasil mengotomatisasi proses klasifikasi diagnosis medis dengan tingkat akurasi yang tinggi dan mampu menangani variasi bahasa serta kompleksitas terminologi medis.
Kata Kunci: Machine Learning, ICD-10, ICD-9CM, Sentence Transformers, Natural Language Processing, Sistem Kesehatan
Управление на кризи или ефективно „неуправляем“ хаос на българската система за национална сигурност
Authors: Tsonkov Nikolay
Published: November 2024

Contemporary conditions are characterized by a high degree of uncertainty, instability, unpredictability, and constant transitions to different types of crises. In such a situation, ensuring national security through effective crisis management is very important for the state's long-term development. Unfortunately, the analyses of the situation and challenges facing the Bulgarian national security system show a critical level caused by objective and subjective characteristics of the state's economic, social and administrative-managerial system, which are different in nature and intensity. The author aims to explore the relationship between crisis management and the state of security in Bulgaria, and on this basis formulate the capacities to overcome the deficits of the national security system. The author concludes that it is necessary to formulate a national doctrine for the long-term development of the Bulgarian state and a new National Security Strategy for the Republic of Bulgaria.
Политически некоректно за националната сигурност. Злободневно есе
Authors: Angelov Pavel
Published: November 2024

In this topical essay, the author directs attention to and invites inquisitive readers to think politically incorrect about national security.
Интегративна схема на някои ключови понятия от науката за сигурността
Authors: Slatinski Nikolay
Published: November 2024

Some groups of concepts occupying an important place in the modern stage of Security Science when entering the Risk Society are considered - "swans" by Nassim Taleb (supplemented by the author); Frank Knight's definitions of risk and uncertainty (also supplemented by the author); Donald Rumsfeld's cognitive quantities; and the scientific categories of the "CReDiT" relation (challenge-risk-danger-threat). Nassim Taleb considers “swan” events - white (frequent and predictable), gray (rare and predictable) and black (rare and unpredictable). To them are added the so-called “silvery swans” (rare and unpredictable), which are often the main focus of attention and basic resource planning. According to Frank Knight, risk is measurable uncertainty, and unmeasurable uncertainty is uncertainty it self. Certainty in this sense is measurable certainty. It remains to characterize the unmeasurable certainty – this is actually insecurity. Donald Rumsfeld considers the following cognitive quantities - the known knowns, the known unknowns, the unknown knowns, the unknown unknowns. If we systematize the concepts challenge, risk, danger, threat by degree of: community; uncertainty; dependence on a given subject; binding with insecurity; immediacy of destructiveness; and time of countermeasures; then their relation (arrangement) can be transmitted through the acronym "CReDiT". The analysis shows that all these concepts - Nassim Taleb's "swans" (supplemented by the author), Frank Knight's definitions of risk and uncertainty (also supplemented by the author), Donald Rumsfeld's cognitive quantities and the scientific categories of the "CReDiT" relation (challenge-risk-danger-threat) can be tied to an integrative scheme. This is in fact completely natural and logical, as long as they all participate effectively in the construction of the essence, meaning and content of the basic scientific category "Security".
Гражданско-военното сътрудничество в помощ на населението при извънредни ситуации
Authors: Ivanov Valeri
Published: November 2024

The author supports the idea that in complex emergencies, military support should be seen as a key component of national resilience. Adequate involvement of military teams in the disaster area can play a vital role in saving human lives, reducing property damages, economic losses and environmental problems. Ensuring good coordination between military and civilian units during disaster response and recovery requires trust among all parties, mutual understanding of objectives and capabilities, joint training and education, legislative development, and more.
تأثير القرآن على الهوية الثقافية والتراث في العالم الإسلامي المعاصر
Authors: القطري اماني عطيه السيد علي
Published: November 2024

The Qur’an has played an important role in shaping the cultural identity and heritage of the Muslim world. Its teachings, based on the principles of unity, diversity, justice and equality, have profoundly influenced social order, language, art, architecture, literature and cultural practices in various parts of the Islamic world They have. Through a comprehensive analysis of case studies from a variety of regions including the Middle East, South Asia and Southeast Asia, the study reveals the enduring impact of the Quran on local customs, customs and social norms By examining the interpretation of Quranic texts and their impact on cultural practices, the study has shed light on the tension between traditional and modern values ​​in the Muslim world. In addition, the continuing importance of the Qur'an in maintaining modern education, media, and cultural identity in a rapidly changing global environment is discussed Finally, the paper offers several options has proposed a future of research, focusing on the evolving relationship between the Qur'an, . cultural heritage and contemporary challenges. Through this insight, the paper emphasizes the importance of preserving Quranic teachings as a cornerstone of cultural development in the Muslim world.
On one minimal hyperbolic Gellerstedt operator with internal degeneracy
Authors: Rogovoy Alexander , Kalmenov Tynysbek
Published: November 2024

The minimal operators generated by overdetermined boundary value problems for differential equations are extremely important in the description of regular boundary value problems for differential equations, and are also widely used in the study of local properties of solutions. The study of overdetermined boundary value problems is closely related to the theory of correct restrictions and extensions and the construction of minimal differential operators. In addition, for inverse problems of mathematical physics arising from applications, when determining unknown data, it is necessary to study problems with overdetermined boundary conditions, including minimal operators, which is reflected in the study of problems, including for hyperbolic equations and systems arising in physics, geophysics, seismic tomography, medicine and many other practical areas. Thus, the study of minimal operators is of both theoretical and applied interest. In this paper, a criterion for the invertibility of the minimal hyperbolic Gellerstedt operator with internal degeneracy is established.   The proof is based on the Gellerstedt potential, properties of solutions to the Goursat problem, and properties of special functions. It should be noted that the Gellerstedt differential operator has numerous applications in transonic gas dynamics, the theory of infinitesimal surface bends, the instantaneous theory of shells with curvature of variable sign, magnetodynamics and hydrodynamics, and the conditions of invertibility of minimal operators imposed on the right side of the initial equation are widely used in the study of the so-called source problem, which arises in a variety of applications inverse problems of mathematical physics.
Influence of Supply Chain Management Practices on Service Delivery at the Judiciary Headquarters in Nairobi, Kenya
Authors: Maalim Mohamud Kuno , Barasa, PhD Dr. Peter Wamalwa
Published: November 2024

Purpose:  Service delivery is a fundamental aspect of public organizations, playing a critical role in fulfilling the expectations and needs of the public. As a result, organizations are called upon to improve the efficiency of their supply chain. The primary goal of this research was to find out how supply chain management techniques affect the quality of services provided at the Kenyan Judiciary Headquarters in Nairobi. The specific objectives were to find out how e-sourcing techniques, collaboration, inventory management and supplier management relationships practices affect service delivery.
Methods: The study was grounded on the transaction costs theory, institutional theory, resource dependence theory, and the Kaizen theory. The study used a descriptive design, targeting 235 employees working at Judiciary Headquarters in Nairobi. A stratified random selection technique was used to pick the 149 participants that made up the sample size. Interview guides and structured questionnaires were used for data gathering. All the data was processed and analyzed in SPSS V.24.
Results: The multiple regression analysis revealed a strong model fit, with an R² value of 0.610, indicating that the independent variables explain 61% of the variance in service delivery. Specifically, e-sourcing practices, collaboration, and supplier relationship management were found to have significant positive effects on service delivery, with standardized coefficients (Beta) of 0.367, 0.328, and 0.312, respectively. Inventory management also had a positive impact, though to a lesser extent (Beta = 0.215). The ANOVA results confirmed the overall model’s significance with an F-statistic of 31.45, p < 0.001. These findings underscore the crucial role of effective supply chain management practices in enhancing service delivery performance.
Conclusion: The study concludes that targeted improvements in these areas can significantly enhance service outcomes, and it recommends further investment in e-sourcing systems, fostering collaboration, and strengthening supplier relationships to improve overall service delivery.
Corresponsabilidad del padre de familia como proyección en la mejora del rendimiento académico
Authors: Avila Soliz Luis Gaspar , Rocío  , Ana
Published: November 2024

En este estudio se examina la importancia de la corresponsabilidad familiar en la mejora del rendimiento académico de los estudiantes. La participación activa y comprometida de la familia en la educación de sus miembros se postula como un factor esencial para el éxito escolar. La investigación subraya el impacto positivo que tiene la implicación familiar en el desarrollo integral de los niños, abarcando no solo el ámbito académico, sino también su bienestar emocional y social. Al fomentar una mayor participación de la familia en la vida educativa de sus miembros, se establece un entorno de apoyo y colaboración que propicia el aprendizaje y el desempeño escolar. La presencia de figuras familiares involucradas y dispuestas a contribuir activamente en la formación de sus miembros puede incidir significativamente en su motivación, autoestima y habilidades para afrontar los retos académicos. Este estudio enfatiza la importancia de reconocer y valorar el papel de la familia como agente de cambio y promotor del éxito académico de sus integrantes. Se sugiere que las políticas educativas y las instituciones escolares estimulen la participación y colaboración de las familias en el proceso educativo, reconociendo su influyente contribución en el rendimiento académico y en el desarrollo integral de los estudiantes
Aislamiento de una comunidad microbiana con capacidad para degradar naproxeno
Authors: Almaraz-Mendoza Eduardo , Santoyo-Tepole Fortunata , Salmerón-Alcocer Angélica , AhuatziChacón Deifilia
Published: November 2024

El uso irracional de los medicamentos ha provocado que fármacos tales como analgésicos, antibióticos,
antiepilépticos, antidepresivos, etc., se encuentren en primera instancia en aguas residuales, llegando hasta aguas
superficiales y aguas subterráneas, teniendo de esta forma como principal fuente de contaminación el consumo y la
posterior excreción de fármacos y sus metabolitos en orina y heces.
El naproxeno es un analgésico no esteroidal que, al igual que otros ácidos farmacéuticos, ingresa a las aguas superficiales
debido a que sólo es parcialmente eliminado por las plantas de tratamiento de aguas residuales. Los procesos fisicoquímicos
para la degradación del naproxeno no han sido eficientes, por lo que es necesario el estudio de nuevas metodologías
capaces de disminuir la cantidad de este fármaco en el medio ambiente, así como su posible acoplamiento a los actuales
sistemas de tratamientos de aguas. En el presente trabajo se aisló una comunidad microbiana con capacidad para degradar
eficientemente el contaminante emergente naproxeno, en condiciones de cometabolismo (naproxeno comercial) y de
monosustrato (naproxeno puro) con eficiencias de remoción del 96% utilizando células inmovilizadas en tezontle.
Capacidad de A. fumigatus para la de degradación de hidrocarburos poliaromáticos derivados del petróleo
Authors: Vázquez-Martínez Adriana , Ferrera-Cerrato Ronald , Cañizares-Villanueva Rosa Olivia , Ríos-Leal Elvira , García-Esquivel Gabriela , Esparza-García Fernando José , Rodríguez-Casasola Felipe Neri
Published: November 2024

La contaminación ambiental afecta los ecosistemas poniendo en riesgo los recursos naturales. La industria petrolera
en México es uno de los principales sustentos económicos y energéticos, ésta se desarrolló sin ningún interés en la conservación
y preservación del medio ambiente. El petróleo está compuesto por una variedad de estructuras moleculares entre ellas los
hidrocarburos aromáticos policíclicos (HAP’s), los cuales tienen un gran impacto negativo en los ecosistemas y causan problemas
de salud por sus efectos mutagénicos, carcinogénicos y teratogénicos. Aspergillus fumigatus es un hongo filamentoso aislado
a partir del suelo de la Ex Refinería 18 de marzo, con el objetivo de emplearlo en un proceso de biorremediación. Se utilizó
queroseno como modelo de estudio, las estructuras aromáticas se caracterizaron con CG-MS en el cual 7 estructuras HAP’s de
bajo peso molecular en un 10-30%, posteriormente conforme a la NOM 138 SEMARNAT/SSA1 2012 se analizó la degradación
de 5 estructuras HAP’s con una mezcla comercial a 50 ppm. A. fumigatus tuvo la capacidad de degradar las estructuras contenidas
en el queroseno al 100% y la degradación de 4 compuestos por debajo de los límites de la norma.
Análisis de la asignatura Comprensión e Interpretación de Textos del Bachillerato SABES
Authors: Bravo Moreno José Porfirio
Published: November 2024

Se presenta un análisis crítico y reflexivo general de la asignatura “Comprensión e Interpretación de Textos” para segundo semestre de bachillerato SABES del estado de Guanajuato, México. Con el documento se observan las áreas de oportunidad del curso, el diseño curricular de la materia, los programas, planeaciones y contenidos, además de las actividades del docente y de los estudiantes.Se trata de analizar los contenidos, la estructura, las repercusiones que tiene en el proceso de enseñanza- aprendizaje de la materia, las estrategias didácticas, la elaboración de material didáctico y recursos y medios para el aprendizaje, los fines últimos de la asignatura y su relación y congruencia para el desarrollo de las competencias que plantea la Reforma Integral de Educación Media Superior (RIEMS, 2008).
Aplicaciones de la ética en la docencia jurídica de México
Authors: Pineda Solorio María Elena , Vega Campos Magdalena
Published: November 2024

En el presente artículo se muestran varios aspectos que tienen que ver con la aplicación de la ética en la docencia jurídica como factor para el desarrollo de una vida académica sustentable, con la cultura de la convivencia pacífica incluyente. Se hace uso de una metodología descriptiva, crítica y analítica, que se refiere al diseño de la investigación, observación crítica de planteamientos teóricos y análisis de posturas éticas, que se llevarán a cabo sobre el tema en el contexto del fenómeno educativo en México. Se exponen tópicos relevantes con una perspectiva pluralista basada en la enseñanza de la ética, con la finalidad de esclarecer cómo es que acontece y bajo qué criterios, esta realidad educativa en la cultura mexicana.
La función social primordial de las Instituciones de Educación Superior (IES) es formar ciudadanos con valores, con una conciencia crítica para comprender y resolver los grandes problemas de nuestro país y del mundo.
Repensar la educación desde la experiencia latinoamericana
Authors: Estrada García María del Rosario
Published: November 2024

En el marco de los trabajos preliminares del XXXIV Encuentro Nacional de Investigación Educativa, organizado por el Instituto Michoacano de Ciencias de la Educación “José María Morelos” (IMCED), llevado a cabo los días 16, 17 y 18 de noviembre de 2022; se concibió este libro: Hacia una nueva pedagogía latinoamericana, que dio título al evento, con la intención de reflexionar en torno a la pedagogía latinoamericana, teniendo como referente principal a uno de sus grandes maestros educadores: Paulo Freire.
Actividades neuroeducativas para fortalecer y rememorar los aprendizajes en los estudiantes
Authors: Álvarez Gaytán José Antonio
Published: November 2024

El presente documento reúne distintas actividades y sugerencias didácticas, a partir de la evidencia neurocientífica vigente, con el propósito de favorecer la práctica educativa en el aula y, por consiguiente, los procesos memorísticos de los estudiantes. El análisis de diversos estudios en neurociencia aplicada a la educación, destacan la relevancia de la memoria y de su estrecha relación con el aprendizaje, por lo que mediante la revisión teórica y el diseño de una propuesta educativa, desde la implementación de actividades y recomendaciones neurodidácticas, se concluye que al adoptar prácticas pedagógicas, basadas en el funcionamiento del cerebro, podría favorecerse el desarrollo cognitivo del estudiantado en la escuela, especialmente, al perpetuar y evocar la nueva información aprendida, mediante procesos educativos, con menor dificultad cognitiva.
Culturally Adapted Cognitive Behavioral Therapy for Moderate Depression and Non-Suicidal Self-Injury Patients
Authors: Kumar Anand , Shaikh Irsa Hyder , Sher Zainab , Malik Mareen A
Published: November 2024

Objective: This study aimed to evaluate the effectiveness of culturally adapted cognitive behavioral therapy (CA-CBT) for treating moderate depression and NSSI in Pakistani patients. Methods: A randomized controlled trial was conducted with 100 participants aged 18-35 years, diagnosed with moderate depression and engaging in NSSI behaviors. Participants were randomly assigned to either the CA-CBT intervention group (n=50) or the standard care control group (n=50). The CA-CBT program integrated Islamic teachings and cultural practices with conventional CBT techniques. Depression and NSSI behaviors were assessed at baseline, post-treatment, and a 3-month follow-up using the Beck Depression Inventory (BDI) and the Self-Injury Behavior Scale (SIBS). Results: The CA-CBT group showed significant reductions in depressive symptoms (p<0.001) and self-injurious behaviors (p<0.001) compared to the control group. Qualitative feedback indicated that participants in the intervention group found the therapy culturally and religiously meaningful, which enhanced engagement and reduced stigma associated with mental health care. Conclusions: The study demonstrates that culturally adapted CBT is an effective intervention for treating moderate depression and NSSI in Pakistani patients. Integrating cultural and religious elements into therapy enhanced treatment adherence and outcomes, suggesting that CA-CBT could be a valuable approach in non-Western, Muslim-majority countries.
Prevalence of Cardiovascular Diseases in District Buner Pakistan
Authors: Bibi Aisha , Saeed Kausar , Saidu Ikram Ali , Saidu Ibrar Ali , Khan Mohsin , Ahmad Naseer , Khan Kashif , Khan Imad Ali
Published: November 2024

Background: Cardiovascular disease (CVD) is a general term that describes a disease of heart and blood vessels. It includes four main types of diseases which are coronary heart disease, stroke, peripheral arterial disease, and aortic disease. Objective: This study aimed to assess the prevalence of cardiovascular diseases in district Buner. and to make the people aware of the cardiovascular diseases.

Methods: This study was conducted with the objective of exploring the prevalence of CVDs in district Buner, KP, Pakistan from September 2022 to September 2023. A total of 850 patients’ data were recorded from different hospitals inhibiting in district Buner through specifically designed questionnaire with the help of already available literature on the topic. These medical centers were frequently visited with proper consent from the physicians. Data was collected randomly on weekly basis from each and every medical center.

Results: Results revealed that among CVDs, the most prominent disease was myocardial infarction (MI) affecting 36% of patients, followed by acute coronary syndrome (ACS) affecting 25.65% of patients, ischemic heart disease (IHD) affecting 7.40% patients, angina affecting 6.70% patients, atrial fibrillation (AF) affecting 5.90% patients, left ventricular failure (LVF) affecting 5.65% patients, coronary artery disease (CAD) affecting 5.55% patients, supraventricular tachycardia (SVT) affecting 5.05% patients, and cardiomyopathy (CMP) affecting 2.10% patients.

Conclusion: This study also reported that patients with CVDs represent 58% male whereas the remaining 42% were female. Most of the people affected by CVDs were having age 61-70 years accounting for 494 (58.15%) patients. The most affected Tehsil was Daggar, with 270 (31.80%) patients, and the rarest cases were reported in Tehsil Khudokhail, with 19 (2.23%) patients. The ultimate reason for this prevalence of CVDs may be due todiabetes mellitus, high blood pressure, obesity, high cholesterol level, and sedentary life style
Clinical Outcomes and Long-Term Prognosis in Patients Undergoing Angioplasty
Authors: Khan Farhat Ullah , Khan Muhammad Idrees , Khan Qasim Ahmad , Farooq Umar , Hafeez Muhammad , Khattak Imran Qadar
Published: November 2024

Objective: To investigate the influence of lifestyle factors, including smoking, physical activity, and dietary habits, on the severity of coronary artery disease (CAD) in patients without comorbidities and to identifying the prevalence of unhealthy lifestyle habits and exploring their relationship with CAD severity.

Methodology: This was a prospective observational cohort study conducted at Hayatabad Medical Complex, Peshawar, from January to June 2022. A total of 200 patients with CAD and no comorbidities were included. Data on lifestyle factors were collected through standardized questionnaires and clinical records. Statistical analyses, including chi-square tests, were applied to assess associations between lifestyle factors and CAD severity.

Results: The results indicated that 45% of patients were smokers, 40% were physically inactive, and 53% had unhealthy dietary habits. Despite the prevalence of these risk factors, no statistically significant association was found between smoking status and CAD severity (p > 0.05). However, the cumulative effect of unhealthy lifestyle factors was evident, with higher CAD severity noted in patients exhibiting multiple risk factors.

Conclusion: The study highlights the significant impact of lifestyle factors on CAD outcomes, reinforcing the need for public health interventions targeting smoking cessation, physical activity, and dietary improvements. Effective lifestyle modifications can potentially reduce the progression of CAD in the local population.
Impact of Diabetes Mellitus on Revascularization Success in Left Anterior Descending, Left Circumflex, and Right Coronary Arteries: A Retrospective Cohort Study
Authors: Shah Tariq , Shah Syed Muzammil , Khan Fahad Raja , Ullah Rafi , Wahab Muhammad Abdul , Rahman Syed Kashif ur
Published: November 2024

Background: Diabetes mellitus (DM) is a significant risk factor for cardiovascular disease and presents challenges in percutaneous coronary intervention (PCI), often leading to suboptimal revascularization outcomes. DM’s association with increased rates of restenosis and major adverse cardiac events (MACE) following PCI necessitates further investigation to guide management in this high-risk population.

Objective: This study aimed to assess the impact of DM on revascularization success and secondary outcomes in patients undergoing PCI of the left anterior descending (LAD), left circumflex (LCX), and right coronary arteries (RCA).

Methods: We conducted a retrospective cohort study at Hayatabad Medical Complex, Peshawar, analyzing clinical data from patients who underwent PCI between January 1, 2021, and December 31, 2021. Participants were categorized into diabetic (N=779) and non-diabetic (N=779) groups. Baseline characteristics, revascularization success rates, and secondary outcomes, including MACE and restenosis, were compared. Statistical analysis was performed using SPSS v27, with continuous variables analyzed via t-tests and categorical variables via chi-square or Fisher’s exact test as appropriate. Logistic regression was employed to adjust for potential confounders.

Results: The revascularization success rate was significantly lower in diabetic patients (74.8%) compared to non-diabetic patients (83.2%) (p < 0.001). Diabetic patients also exhibited a higher incidence of MACE (12.9% vs. 6.9%) and restenosis (9.5% vs. 5.1%) compared to their non-diabetic counterparts (p < 0.001 for both outcomes). Increased BMI and LDL levels among diabetic patients were notable factors associated with adverse outcomes.

Conclusion: Diabetes mellitus is associated with reduced revascularization success and increased adverse outcomes following PCI in LAD, LCX, and RCA arteries. These findings highlight the need for specialized therapeutic approaches and intensive follow-up in diabetic patients undergoing PCI to improve long-term outcomes.
Impact of Smoking on Long-Term Revascularization Success and Complications in Multivessel Percutaneous Coronary Intervention: A Retrospective Cohort Study
Authors: Shah Tariq , Shah Syed Muzammil , Khan Fahad Raja , Ullah Rafi , Wahab Muhammad Abdul , Rahman Syed Kashif ur
Published: November 2024

Background: Smoking is a major modifiable risk factor in coronary artery disease (CAD) and is associated with adverse outcomes following percutaneous coronary intervention (PCI). PCI, widely utilized for revascularization in multivessel CAD, aims to restore coronary blood flow and reduce ischemic complications. However, smokers face increased risks of restenosis and major adverse cardiac events (MACE) after PCI, highlighting a need for further investigation into these associations.

Objective: This study aimed to assess the impact of smoking on revascularization success and complications in patients undergoing multivessel PCI.

Methods: A retrospective cohort study was conducted at a tertiary cardiovascular center, evaluating clinical data from patients who underwent PCI from January 1, 2023, to December 31, 2023. Patients aged 18 and older with confirmed multivessel CAD were included. Participants were divided into smokers (N=779) and non-smokers (N=779) based on documented smoking status. All patients underwent PCI with either drug-eluting stents (DES) or drug-eluting balloons (DEB), followed by standard dual antiplatelet therapy. The primary outcome was revascularization success, defined as achieving TIMI grade ≥2. Secondary outcomes included incidences of MACE and restenosis. Statistical analyses were performed using SPSS v27, with t-tests and chi-square tests used for continuous and categorical variables, respectively. Logistic regression adjusted for confounders.

Results: Revascularization success was significantly lower in smokers (69.8%) compared to non-smokers (81.6%) (p < 0.001). Smokers also exhibited higher rates of MACE (15.5%) and restenosis (12.6%) versus 8.4% and 7.3% in non-smokers, respectively (p < 0.001 for both outcomes).

Conclusion: Smoking negatively affects revascularization success and increases MACE and restenosis risks in multivessel PCI patients. These findings underscore the importance of tailored therapeutic strategies and smoking cessation efforts to improve PCI outcomes in this high-risk group.
The Role of Artificial Intelligence in Advancing Dermatology
Authors: Sani Dr annas
Published: November 2024

Artificial intelligence (AI) is poised to revolutionize dermatology by enabling precision diagnostics, improving clinical workflows, and enhancing accessibility to care, especially in underserved regions. Dermatology’s reliance on visual data, such as clinical and dermoscopic images, makes it an ideal speciality for integrating AI-powered tools, particularly those based on machine learning (ML) and deep learning (DL).