bluuebunny/crossref_metadata_2025 huggingface dataset:
Observation on the effect of comprehensive nursing intervention for patients with chronic obstructive pulmonary disease
Authors: Hu Cuirong , Zhu Shu , Li Guixiang
Published: July 2021

AbstractÂ Objective: This study focused on the observation effect of comprehensive nursing intervention in patients with chronic obstructive pulmonary disease.METHODS: A total of 64 patients with chronic obstructive pulmonary disease were selected as subjects. The patients were divided into two groups according to a randomized method. The observation group and the control group were the same in both groups (n=32), study time from June 2017 to August 2018, the selection of patients in the study time, the standard treatment and routine care to give way to the control group. The observation groups comprehend nursing intervention. The two groups of patients compared with nursing effects, nursing satisfaction, lung function levels before and after care, care adherence, hospitalization days and satisfaction scores.RESULTS: The observation group was better than the control group in terms of nursing effect, nursing satisfaction, lung function level before and after nursing, nursing compliance, hospitalization days and satisfaction score.
DISASTER & NURSEâ€™S ROLE
Authors: Vandali Vijayreddy , Biradar Rekha B
Published: July 2021

ABSTRACT: India is vulnerable to a large number of disasters. More than 58.6 % of the landmass is prone to earthquakes of moderate to high intensity; over 40 million hectares (12%) of its land is prone to floods and river erosion; close to 5,700 kms, out of the 7,516 kms long coastline is prone to cyclones and tsunamis; 68% of its cultivable area is vulnerable to droughts; and, its hilly areas are at risk from landslides and avalanches. WHO defines Disaster as â€œany occurrence that causes damage, ecological disruption, loss of human life, deterioration of health and health services, on a scale sufficient to warrant an extraordinary response from outside the affected community or area. Roles of nurse during disaster management includes to determine the magnitude of the event, define & understand the health needs of the affected groups, prepare the priorities and objectives, Identify actual and potential public health problems at the earliest & estimate resources needed to respond to the needs identified.
Study on the effect of the intervention on traditional Chinese medicine negative heel shoes
Authors: Zhai Jiabin , Ren Lianjun , Wang Qirong
Published: July 2021

Abstract: In the clinical practice of orthopaedics, geriatric patients are prone to form and exhibit complex and diverse clinical complications during long-term bedridden treatment. This can result in poor survival rate and adverse final clinical outcomes. Hence, it is essential to select appropriate methods for nursing intervention and health care support for long term bedridden geriatricorthopaedic patients. It is of great significance to support and guarantee patients to obtain the best clinical results. This article focuses on the topic of interventional health effects of traditional Chinese medicine negative-heeled shoes in orthopaedic bedridden patients and two specific aspects were selected for a brief explanation.
Clinical study of microvascular decompression for the treatment of trigeminal neuralgia
Authors: Song Litao , Zhong Jingyang , Sun Jianbin , Han Zhanqing , Xiao Liandong , Han Yinchuan
Published: July 2021

Objective: To explore the value of microvascular decompression in the treatment of trigeminal neuralgia. Methods: The clinical data of 80 patients with trigeminal neuralgia who admitted to our hospital from February 2015 to February 2019 were retrospectively analyzed. The patients were randomly divided into two groups. The control group received routine treatment, and the observation group underwent microvascular decompression. Results: The total effective rate of the observation group was higher than that of the control group, P < 0.05. The recurrence rate of the observation group was lower than that of the control group, P < 0.05. Conclusion: Microvascular decompression for the treatment of trigeminal neuralgia can significantly improve the efficacy and reduce the recurrence.
The Effect of Prostate Volume on Robotic-assisted Radical Prostatectomy
Authors: Zhang Yongjian , Zhang Guiming , Sun Lijiang
Published: July 2021

Objective: To investigate the effect ofprostate volume on robot-assisted radical prostatectomy.Methods: Clinical data of 75 patients underwent RARPin the Affiliated Hospital of Qingdao University wereretrospectively analyzed. The patients were dividedinto 3 groups according to size of prostate. A total of35 cases with prostate volume less than 30ml wererecorded as group 1, 27 cases with volume of 30 to50 ml were recorded as group 2, and 13 cases withvolume greater than 50ml were recorded as group3. Age, BMI, preoperative PSA, operation time,intraoperative bleeding volume, postoperative drainagevolume, indwelling time of catheter, indwelling time ofdrainage tube, total hospitalization time, pathologicalstage, surgical margin, urine control and biochemicalrecurrence were observed. Results: All operationswere performed under Da Vinci robot assistance, andno patient was transferred to open surgery. There wasno significant difference in age, preoperative PSA,BMI, operation time, intraoperative bleeding volume,postoperative drainage volume, indwelling time ofcatheter, total hospitalization time, pathological stage,rate of positive surgical margin and recovery of urinarycontinence between the groups. Indwelling time ofdrainage tube was longer in group with larger prostate,6.4 (±4.5) days in group 1, 6.3 (±2.9) days in group 2and 7.1 (±2.5) days in group 3. Gleason score was lowerin group with larger prostate, with statistical difference.Conclusion: Prostate volume had no significant effecton urinary control, rate of positive surgical margin andrecurrence after RARP. Gleason score of pathologicaltissue was lower and indwelling time of drainage tubewas longer in patients with larger prostate after RARP.Operation time and intraoperative bleeding volumeof large prostate patients underwent RARP need tobe further studied. RARP has certain advantages forpatients with large prostate.
Evaluation of Clinical Efficacy of Combination of Surgery and Rehabilitation for Treatment of Scar Contracture after Hand Burn
Authors: Li Yong
Published: July 2021

Objective: To evaluate the clinical efficacy of combination of surgery and rehabilitation for patients with scar contracture after hand burn. METHODS: Subjects of data calculation in this study were 66 patients with scar contracture after hand burn who were admitted from May 2018 to May 2019. The subjects were divided into regular group and combined group according to random number table method. The regular group (n=33) received surgical treatment alone. The combined group (n=33) patients were given surgery combined with rehabilitation. Recovery of hand function, efficacy of clinical treatment, hand function recovery and ADL score were calculated and compared between the two groups of patients with scare contracture after hand burn. RESULTS: Efficacy, recovery of hand function (finger, finger flexion and extension, palm and finger adduction or abduction, daily activity, wrist rotation, wrist flexion and extension, appearance and sensory function) and ADL score were more superior in combined group when compared with regular group patients with scar contracture after hand burn. P <0.05, the indicator data showed statistical significance. Conclusion: Surgery combined with rehabilitation therapy shown significant value for patients with scar contracture after hand burn.
Evidence-based Care for Rehabilitation Nursing Effect of Patients with Patellar Fracture
Authors: Dong Rongrong , Xu Haiyan , Chen Huaqin
Published: July 2021

Objective: To analyze the effect of applying evidence-based care in rehabilitation nursing effect of patients with patellar fractures. Methods: A total of 54 patients with patellar fractures were randomly selected from the hospital. The diagnosis and treatment time were from the beginning of July 2018 to end of June 2019. The digital table grouping was adopted to divide patients into two groups with each group consists of 27 patients with this disease. Both groups underwent routine nursing and the experimental group with increased evidence-based care. Results: Compared with the control group, the knee function evaluation, complications and nursing satisfaction of the experimental group were more ideal, and the difference was statistically significant (P<0.05). Conclusion: Evidence-based care in rehabilitation nursing of patients with patellar fracture can obtain ideal nursing effect.
Comparative analysis of CT in the diagnosis of papillary thyroid carcinoma and nodular goiter
Authors: Ren Guoqiang , Liu Wenhua
Published: July 2021

Objective: To investigate the Computed Tomography (CT) features of papillary thyroid carcinoma and nodular goiter. METHODS: Ninety patients were enrolled in this study. All patients were treated with thyroid disease admitted to our hospital from January 2016 to December 2018. Among them, sixty patients with thyroid papillary carcinoma and thirty patients with nodular goiter were examined by CT scan and enhanced examination. RESULTS: There was no statistically significant difference in the volume index of left lobe, right lobe and isthmus in thyroid patients (P>0.05). There were significant statistical differences in the growth site, morphology, border, density, calcification and enhancement mode of nodules ( P < 0.05). Conclusion: CT examination has significant diagnostic value in the differential diagnosis of papillary thyroid carcinoma and nodular thyroid.
Precision Medication of Tacrolimus Based on the Genotype by Using Second-generation Sequencing
Authors: Li Yumeng
Published: July 2021

Organ transplantation has become a powerful strategy for the treatment of malignant diseases. Nevertheless, graft rejection is one of the main factors affecting graft survival after organ transplantation. Under this circumstance, the transplant-related mortality still keeps up. This invention includes the precise medication guidance of Tacrolimus (FK506) inapplicable population, against the side-effects of this drug. This invention, based on second-generation sequencing, has the advantages of relatively low cost and high sequencing throughput. During the design process, we collect the data of single nucleotide polymorphism (SNP) concerning the adverse drug reactions of Tacrolimus. Then we filter and summarize fifteen SNPs basing on importance degree (level >key enzyme>race). Thenceforth, after the process of analyzing the raw extract by operating BWA, Picard-tools, GATK, and Perl, we annotate SNPs by Annovar. Through this innovation, people can obtain further feedback on drugs that targets different genes in order to achieve the purpose of precision medication and minimizing the risks of misusing Tacrolimus.
A Case Report of Posterior Reversible Encephalopathy Syndrome with Rapidly Progressive Glomerulonephritis Combined with Membranous Nephropathy
Authors: Xu Ruirui , Shao Zhufu , Sun Lin , Li Rui , Wang Qingfeng
Published: July 2021

Rapidly progressive glomerulonephritis is a group of clinical syndromes, in which renal function of patient progressively deteriorates with pathological manifestation of extensive glomerular crescent formation. Among which, anti-glomerular basement membrane antibody glomerulonephritis is the rarest but the most aggressive subtype. This paper discusses a case of rapidly progressive glomerulonephritis combined with membranous nephropathy. There were posterior reversible encephalopathy syndromes during diagnosis and treatment. Diagnosis was confirmed in time by laboratory examination and renal pathology. Condition of the patient was alleviated through close work between all departments. This allowed us to further understand the case characteristics of rapidly progressive glomerulonephritis combined with membranous nephropathy, importance of effective prevention, and significance of various complications during treatment, so as to alleviate pain and improve prognosis in patient.
Nursing Effects of Medical Treatment Combination on Patients at High Risk of Developing Pressure Ulcers at Rural Homes
Authors: Qin Hua , Hu Xiuqiong
Published: July 2021

Objective: To explore the nursing effects of medical treatment combination on patients at high risk of developing pressure ulcers at rural homes. Methods: From January 2018 to December 2018, 86 patients at high risk of developing pressure ulcers at rural homes who were in Wenjiang Hospital were randomly divided into a control group and an observed group. The control group received the routine publicity and education and visiting, while the observed group adopted the cooperative nursing model of medical treatment combination. Then compare the healing status and nursing satisfaction of the two groups. Results: Of the 43 patients with pressure ulcers in the observed group, 18 had been in the second stage of pressure ulcers and 16 had been healed; 14 had been in the third stage of pressure ulcers and 8 had been healed; 11 had been in the fourth stage of pressure ulcers and 5 had been healed. The nursing satisfaction of the patients in the observed group was 95.35%. Conclusion: Conducting medical treatment combination on patients at high risk of developing pressure ulcers at rural homes can effectively improve the patients’ and their families’ awareness of pressure ulcer nursing, standardize their nursing behaviour, help recover the patients themselves and promote the patients’ satisfaction.
Clinical Efficacy of Acupuncture Combined with Massage on Cervical Spondylopathy of Vertebral Artery Type and Its Effect on Hemodynamics of Patients
Authors: Wei Yi
Published: July 2021

Objective: To investigate the clinical efficacy of acupuncture combined with massage on cervical spondylopathy of vertebral artery type and its effect on hemodynamics of patients. Methods: Sixty patients with vertebral artery type cervical spondylosis treated in our hospital from July 2017 to October 2019 were selected as the research subjects and randomly divided into 2 groups of 30 cases each. The control group was treated with acupuncture, and the observation group was treated with acupuncture combined with massage, and the clinical efficacy and hemodynamic index of the two groups were compared after 1 month of treatment [peak systolic blood velocity (PSV), pulsatile index (PI), time mean flow velocity (TMFV)]. Results: There was no statistical difference in the PSV, PI, and TMFV between the two groups before treatment (P> 0.05). After treatment, the observation group had a higher treatment efficacy than the control group with PSV and TMFV increasing and PI decreasing in both groups, and the change in the observation group was greater than that in the control group, and the difference was statistically significant(P<0.05). Conclusion: Acupuncture combined with massage on cervical spondylopathy of vertebral artery type can improve the clinical efficacy and improve the hemodynamic index of patients, which is worthy of clinical application.
Nursing of Artificial Liver Support System in the Treatment of Severe
Authors: Rao Jieyu , Chen Yanyun , Cai Xiaoxi , Luo Jinglan
Published: July 2021

Objective: Research on nursing method of artificial liver support system applied in severe hepatitis patients. Methods: Selected 50 severe hepatitis patients in our hospital during the period of January 2018 and January 2019, observed and analyzed the clinical intervention effect of all treated by artificial liver support system cooperating with related nursing methods. Results: After the treatment, the clinical symptoms and abdominal distension of the patients were relieved, whose spirit took a turn for the better and the jaundice subsided. Among these patients, 68% got improved enough to be released, 26.00% gave up for financial concerns and 6.00% died. Before and after treatment, the patients’ PT and PTA improved obviously, and the difference were quite a lot (P<0.05), while ALT and ALB showed few without any statistical significance (P>0.05). Conclusion: During the treatment and intervention of severe hepatitis patients with artificial liver support system, effective nursing interventions are needed, mainly including completely preoperative, intraoperative and postoperative care so as to ensure the treatment effect and promote the recovery of intervention, which has remarkable significance to clinical development.
Are Pharmaceutical Treatments or Psychological Approaches a More Effective Way of Treating Depression?
Authors: Wu Ruochen
Published: July 2021

Objective: To review the related researches on the treatment of depression around the world and to summarize the advantages and disadvantages of antidepressants and psychotherapy, so that to find a more effective treatment plan for depression. Methods: The principles of several common pharmaceutical treatment combined with psychological approach were analyzed, cognitive behavioral therapy, interpersonal psychotherapy and social support therapy included. Discussion: Some experimental results were illustrated and the advantages of Pharmaceutical treatment combined with psychological approach was revealed. Conclusion: Research indicates when pharmaceutical treatment is available, the combination of drugs and psychotherapy is more effective than sole pharmaceutical treatment.
Enalapril Combined with Hydrochlorothiazide and Indapamide in the Treatment of Hypertension with Heart Failure
Authors: Sun Xueting
Published: July 2021

Objective: To explore the effect of enalapril combined with hydrochlorothiazide and indapamide on hypertension and heart failure. Methods: 80 patients with hypertension and heart failure admitted to our hospital from January 2019 to January 2020 were selected as the research subjects, and they were divided into two groups with random number table method, 40 cases each. The control group was given conventional treatment regimens, including enalapril and hydrochlorothiazide; the observation group replaced hydrochlorothiazide with indapamide based on the above therapies. The efficacy and systolic blood pressure, diastolic blood pressure and left heart ejection fraction (LVEF) of the two groups were compared. Results: After treatment, the effective rate of the observation group was 92.50% (37/40) higher than that of the control group 75.00% (30/40). The systolic and diastolic blood pressure were lower than those of the control group, and the LVEF was higher than that of the control group. The difference was statistically significant (P<0.05). Conclusion: Enalapril combined with indapamide is effective in the treatment of hypertension with heart failure, which can help lower blood pressure, reduce heart load, increase cardiac output, reverse ventricular remodeling, and delay disease progression.
The Effect of Intensive Psychological Nursing on the Mood and Solutions of Spinal Tuberculosis Patients
Authors: Fan Jianping
Published: July 2021

Objective: To investigate the effect of intensive psychological nursing on the mood and coping ways of spinal tuberculosis patients. Methods: The clinical data of 102 patients undergoing spinal tuberculosis surgery in our hospital from February 2017 to January 2020 were retrospectively analyzed. All the cases were grouped according to different nursing plans, patients who received routine care were included in the control group (n = 50), and the ones with intensive psychological care were included in the observation group (n = 52). Compare negative emotions after nursing [assessment using self-assessment scale of anxiety (SAS), depression self-assessment scale (SDS)] and solutions [assessment using medical response questionnaire (MCMQ)] of the two groups. Results: After nursing, the SAS, SDS scores, avoidance and yield scores of the two groups were reduced, and the coping scores were increased, and the change of the observation group was greater than that of the control group, the difference was statistically significant (P<0.05). Conclusion: Spinal tuberculosis surgery patients were treated with intensive psychological care, which can relieve patients' negative emotions, improve solutions and are worthy of clinical use.
Analysis of the Value of Elojumab in Patients with Acute Coronary Syndrome after Percutaneous Coronary Intervention
Authors: Fu Baojun , Song Daqing , Sun Shuyin
Published: July 2021

Objective: To analyze the application value of Elouzumab in patients with acute coronary syndrome (ACS) after percutaneous coronary intervention (PCI), so as to lay a foundation for the follow-up treatment. Methods: 84 ACS patients who underwent PCI in our hospital from December 1, 2018 to December 1, 2019 were selected and divided into control group (n = 42) and study group (n = 42) according to the random number table. The control group was treated with statins, and the study group was treated with alloxan combined therapy. The changes of blood lipid index, quality of life score, adverse cardiovascular and cerebrovascular events and adverse reactions were compared before and after treatment. Results: There was no significant difference in TCHO, TG, HDL-C and LDL-C between the two groups before treatment (P>0.05);After treatment, the levels of TCHO, TG, HDL-C and LDL-C in the study group were significantly lower than those in the control group (P<0.05);There was no significant difference in the scores of WHOQOL-BREF before treatment (P>0.05);After treatment, the WHOQOL-BREF scores of the two groups were improved, and the study group was significantly higher than the control group (P<0.05);The incidence of adverse cardiovascular and cerebrovascular events and adverse reactions in the study group was lower than that in the control group, but the difference was not statistically significant (P>0.05). Conclusion: After percutaneous coronary intervention in patients with acute coronary syndrome, the use of Elojumab can effectively reduce the blood lipid index, improve the quality of patients and reduce the incidence of adverse cardiovascular and cerebrovascular events and adverse reactions, which can be effectively promoted in clinical practice.
Diagnostic Value of Spectral CT Reconstruction Mode for Carotid Atherosclerotic Plaque Lesions
Authors: Bi Junying , Zeng Yanni , Meng Jun , Zhou Tiantian , Gao Xiang
Published: July 2021

Objective: To investigate the diagnostic value of spectral CT reconstruction mode for carotid atherosclerotic plaque lesions. Methods: From January 2017 to January 2019, 70 patients with carotid atherosclerotic plaque lesions in our hospital were selected as the research object. All patients were diagnosed with cervical vascular color Doppler ultrasound and spectral CT scan under spectral CT reconstruction mode. Taking the results of coronary angiography as the “gold standard”, the clinical value of the two examination methods in the diagnosis of carotid atherosclerotic plaque lesions was compared and analyzed. Results: Coronary angiography diagnosis confirmed that 33 of 70 patients with suspected carotid atherosclerotic plaque lesions had vulnerable plaques and 37 had stable plaques. The accuracy of Spectral CT examination of carotid artery plaque was 87.14% (61/70), sensitivity was 90.91% (30/33), specificity was 83.78% (31/37), and the positive predictive value was 83.33% (30 /36), the negative predictive value is 91.76% (31/34), which is higher than that of cervical vascular ultrasonography (61.43%, 60.61%, 56.76%, 57.89%, 65.63%), the difference is statistically significant (P<0.05). Conclusion: The application of Spectral CT in the clinical diagnosis and treatment of carotid atherosclerotic plaque lesions with higher accuracy, sensitivity and specificity, is more significant and can provide a more reliable and effective imaging basis.
Development and Clinical Application of Shapeable Head Braking Device
Authors: Wen Zuozhen , Wang Yan , Mao Xiaoyan , Zhang Liping , Huang Xiaojing , Huang Zhuoshan
Published: July 2021

Objective: To evaluate the application effect of a plastic head brake device after radical resection of oral malignant tumors and flap repair for defects. Methods: 2018-2019 years, 5 months Sun Yat-sen Memorial patients oral and maxillofacial surgery for oral malignant tumor resection surgery period skin flaps hospital 150 patients randomly divided into groups. Test groups 70 examples and the control group of 80 cases, two different head braking methods were used. The experimental group used a self-designed head brake device, which was prepared to suit the height of the patient before operation. It was used from 0 to 3 days after operation. After the operation, the head lateral range was adjusted according to the braking requirements, and the pillow height was adjusted. The control group wrapped a 500 g salt bag with a treatment towel on both sides of the patient's head for head braking. The incidence of flap vascular crisis, head and neck deviation, head occipital pressure ulcer incidence and patient comfort during braking were evaluated in both groups. Results: The occurrence of vascular crisis in patients with oral tumors was significantly correlated with the patient's gender, alcoholism, and head movement (P<0.05), and the movement of patients' head and neck was also significantly correlated with the occurrence of vascular crisis. Compared with the control group, the experimental group had significant differences in head and neck deviation, incidence of vascular crisis, incidence of head ulcer pressure ulcers and patient comfort (P<0.05). Conclusion: The degree of head movement and incidence of vascular crisis in patients Closely related. Mouldable head brake device has more than ordinary salt bag ProA better head and neck braking effect can significantly reduce the incidence of postoperative vascular crisis, improve patient comfort, and have a better clinical application effect. In addition, this device can also be used repeatedly, reducing economic costs and better improving the satisfaction of doctors, nurses and patients.
Risk Assessment of Perioperative Infection about 263 Diabetic Patients Undergoing Small Bowel Lateral-lateral Anastomos(intestinal bypass)
Authors: Xie Haolin , Lv Hongliang , Zhang Hongyi , Jin Hu
Published: July 2021

Objective: Analyze and summarize the risk assessment of perioperative infection of 263 diabetic patients undergoing small bowel lateral-lateral anastomos(intestinal bypass )in the small intestine's side ,discuss the managerial methods of antimicrobial agents during the perioperative period. Methods: Retrospectively analyze the clinical data of patients who underwent laparoscopic small bowel lateral anastomosis (intestinal bypass) from January 2018 to December 2018. The patients with HBA1c ?9.0% were selected as the observation group and patients with HBA1c < 9.0% as the control group. Results: The decling range of the average value about blood glucose in the observation group was greater than that in the control group. The difference was statistically significant (P<0.05). The average postoperative neutrophil ratio of the observation group was higher than that of the control group; and the difference was statistically significant(P<0.05). The proportion of patients with postoperative body temperature over 37 degrees in the observation group was higher than that in the control group. Conclusion: Laparoscopic lateral anastomosis (intestinal bypass surgery) may cause intestinal fluid overflow and intestinal flora ectopic, for the diabetic patients with poor blood glucose control, perioperative risk of infection increased, we should consider strengthening the grade of antimicrobial agents in preventive application, better cover gram-negative bacteria and anaerobic bacteria.
On the Treatment of Insomnia with Fang’s Scalp Acupuncture Based on the Therapy of “Regulating Mental Activities and Smoothing the Liver”
Authors: Zhou Yanyan , Ren Yuanyuan , Zhang Kaiya
Published: July 2021

As a common clinical disease, insomnia was usually treated with anti-psychotic or sedative-hypnotic drugs in Western medicine, which showed a fast efficacy, as well as easy drug tolerance and side effects. In traditional Chinese medicine, the basic and key pathogenesis of insomnia are believed to be “the restlessness of the mind”, as well as “the absence of the mind”; and the treatment mainly focus on “regulating mental activities and smoothing the liver”. By combining the theoretical basis and characteristics of Fang’s scalp acupuncture, this paper aims to explain the advantages of Fang’s scalp acupuncture in the treatment of insomnia, and provide new ideas and methods for its clinical treatment.
Endovascular Application of Magnetic Resonance Double Mismatch Technique for Acute Anterior Circulation Large Vessel Occlusion with Cerebral Infarction in an Unknown Time Window
Authors: Song Xiangkong , Zhang Qing , Gao Lilin , Qi Jie , Wang Guoqing
Published: July 2021

Objective: To investigate the clinical effects of applying the magnetic resonance double mismatch technique to endovascular treatment of acute anterior circulation, large vessel occlusion with cerebral infarction in an unknown time window. Methods: The research work was carried out in our hospital, the work was carried out from November 2018 to November 2019, the patients with acute anterior circulation large vessel occlusion with cerebral infarction who were treated in our hospital during this period, 100 patients, 50 patients with an unknown time window and 50 patients with definite time window were selected, and they were named as the experimental and control groups, given different examination methods, were given to investigate the clinical treatment effect. Results: Patients' data on HIHSS score before treatment, the incidence of intracranial hemorrhage and rate of Mrs?2 rating after 90 days of treatment were not significantly different(P>0.05), which was not meaningful. The differences in data between the two groups concerning HIHSS scores were relatively significant before, and after treatment(P<0.05). Conclusion: The magnetic resonance double mismatch technique will be applied in the endovascular treatment of acute anterior circulation large vessel occlusion with cerebral infarction of unknown time window.
The Expression and Clinical Significance of Sema4A in Triple Negative Breast Cancer
Authors: Chen Hong , Gao Chunhui , Wang Lingyan , Zhao Wenming , Zhang Bingxin , Zhang Jinku
Published: July 2021

Objectives: To explore the expression and clinical significance of Sema4A in triple-negative breast cancer. Methods: Eighty patients with invasive ductal carcinoma of the breast and 40 normal tissues adjacent to cancer were selected. Immunohistochemical methods were used to detect the expression of Sema4A in breast cancer and normal tissues adjacent to cancer, and its relationship with breast cancer clinicopathological features and prognosis. Results: The expression of Sema4a in the serum of BCA patients was significantly higher than that of healthy controls. In addition, the expression of sema4a in BCA cells and in the cell supernatants was also up-regulated under hypoxia. Conclusion: Exogenous Sema4A can protect BCA cells from hypoxia-induced cytotoxicity, inhibit cell apoptosis and promote cell proliferation.
Clinical Observation of the Treatment of Hemorrhoids with Polyvinyl Alcohol Foam Sclerotherapy under Transparent Cap Assisted Endoscope
Authors: Qi Yanmei , Zhou Fengqiang , Geng Zhen , Liu Lei
Published: July 2021

Objective: To explore the clinical effect of domestic capsosol foam sclerotherapy in the treatment of hemorrhoids under transparent cap assisted endoscope. Methods: According to the experimental requirements, 120 cases of hemorrhoids hospitalized in gastroenterology department in our hospital from February to December in 2019 were selected as the treatment group. The foam sclerotherapy of polidocanol and the air in accordance with the 1:4 ratio was injected into varicose hemorrhoids and hemorrhoids through a transparent cap assisted endoscope. At the same time, 100 patients were selected as the control group and the patients were treated according to the routine protocol. The symptom score and clinical efficacy of the two groups were observed under different treatment schemes. Results: 120 patients were successfully injected with foam sclerotherapy under endoscope. There were significant differences in clinical symptom score and clinical efficacy between the injection sclerotherapy group and the control group. There were statistically significant differences in the bleeding, prolapse, painful defecation, anal foreign body sensation, impact on daily work, and hemorrhoids data between the treatment group and the control group (P<0.05). Conclusion: Transparent cap assisted endoscopic injection of polidocanol sclerotherapy in the treatment of hemorrhoids can effectively improve the clinical symptoms of patients, promote the improvement of the disease, and the curative effect is satisfactory. It is a new method of minimally invasive treatment of hemorrhoids, which is worthy of wide promotion in clinical practice.
Evaluation on the Effects of Pulmicort Respules, Ventolin combined with Methylprednisolone in the Adjuvant Treatment of Bronchiolitis in Children
Authors: Miao Shimin
Published: July 2021

Objective: To investigate the effects of Pulmicort Respules, Ventolin combined with methylprednisolone in the adjuvant treatment of bronchiolitis in children. Methods: A total of 100 children with bronchiolitis in our hospital from March 2018 to March 2020 were selected and divided into 2 groups with 50 cases in each group by using random number table. Both groups received conventional treatment. Based on this, the control group was given Pulmicort Respules and Ventolin, and the observation group was given methylprednisolone in combination with the conventional regimens on the basis of the control group treatment, the course of treatment was 5 days. The levels of inflammatory factors [tumor necrosis factor-a (TNF-a), interleukin 6 (IL-6)] and the time to symptom disappearance before and after treatment were compared and analyzed between the two groups. Results: After treatment, the levels of serum TNF-a and IL-6 in the two groups decreased, and the observation group was lower than the control group, the difference was statistically significant (P<0.05); the disappearance of pulmonary moist rales, lung wheezing, cough and wheezing in the observation group were all earlier than the control group, the difference was statistically significant (P<0.05). Conclusion: Pulmicort Respules, Ventolin combined with methylprednisolone is effective in adjuvant treatment of bronchiolitis in children, which can reduce inflammation and promote the recovery of children.
Analysis on the Clinical Effects of Emergency Surgical Treatment on Patients with Acute Abdominal Pain
Authors: Hu Xuan
Published: July 2021

Objective: To study the clinical effects of emergency surgery in treating patients with acute abdominal pain. Methods: 60 patients admitted to our hospital between January 2019 and December 2019 were randomly selected as subjects, and the incidence of complications and mortality of the patients were observed. Results: Among the 60 patients, definitive diagnosis was obtained during the operation and there was no mortality. After the operation, they were transferred to other relevant departments for continued treatment. Among the 60 patients, 4 cases had complications, accounted for incidence of 6.67%. Conclusion: The diagnosis of emergency surgical treatment based on acute abdominal pain avoided misdiagnosis and realized non-invasive diagnosis, and provided a valid reference for avoiding overtreatment.
Treatment of Sjogren's Syndrome with Liver Depression
Authors: Liu Jiaqin , Liu Chunying
Published: July 2021

Liu Chunying is a famous old Chinese medicine doctor for more than 30 years. He has rich experience in the understanding and treatment of Sjogren's syndrome (SS). Liu Shi systematically discusses the etiology and pathogenesis of SS from the angle of liver depression. In the treatment, it is emphasized that "Muyu Da Zhi" is the first, with the addition and subtraction of the disease, to provide a new idea for the treatment of Sjogren's syndrome from liver depression, and to attach a test case.
Clinical Observation of Dexmedetomidine Combined with the Mixture of Propofol and Etomidate on Painless Gastroscopy in Children
Authors: Sha Liao , Wu Zhifang , Zhang Xianhui , Wei Lishuai
Published: July 2021

Objective: To observe the anesthetic effect of dexmedetomidine combined with the mixture of propofol and etomidate on painless gastroscopy in children. Methods: A total of 80 pediatric patients who underwent painless gastroscopy in the Guangxi Minzu Hospital from January 2019 to September 2020 were randomly divided into two groups, A and B, with 40 patients in each group. Group A was given A mixture of etomidate 20 mg and propofol 0.2g, Dexmedetomidine was pumped into group B 10min before surgery, 0.4 g/kg. HR, SBP, DBP, SpO2 and BIS were continuously monitored after entering the room. The doses of propofol and etomidate were recorded, as well as the time of waking and leaving the hospital. Adverse reactions such as hypotension, hypoxemia, nausea, vomiting and dizziness were recorded too. Results: Compared with group A, the dosage of propofol and etomidate in group B was significantly reduced (P < 0.001), the time of waking and out of the chamber were significantly shortened (P < 0.001), the body movement in the incidence of intraoperative was significantly reduced (P < 0.001), and the nausea, vomiting and dizziness in the incidence of postoperative were significantly reduced (P < 0.05). Conclusion: Dexmedetomidine combined with propofol and etomidate mixture can be safely used in painless gastroscopy in children, which can significantly reduce the dosage of propofol and etomidate, reduce the occurrence of adverse reactions, and shorten the time of resuscitation and discharge.
Association Study between miR-181b rs322931 Polymorphism and Risk of Gastric Cancer
Authors: Pan Dingguo , Li Yunfeng , Ai Liang , Zhang Qi
Published: July 2021

Objective: To explore the relationship between miR-181b rs322931 polymorphism and the risk of gastric cancer. Methods: The peripheral venous blood of 172 patients with gastric cancer and 224 healthy controls were collected. The miR-181b rs322931 was typed by TaqMan probe method, and correlation between miR-181b rs322931 and the risk of gastric cancer was evaluated using SPSS software.  Results: The frequencies of miR-181b rs322931 CC, CT, TT genotype, C, and T allele were 61.6, 33.7, 4.7, 78.5, and 21.5% in gastric cancer, and 74.1, 23.7, 2.2, 85.9, and 14.1% in controls, respectively. After the ?2 test and correction for age and gender, the risk of gastric cancer in carriers of CT and CT/TT genotypes increased by 1.71 and 1.79 times, respectively (CT vs. CC: 95% CI, 1.10-2.67, P=0.02; CT /TT compared with CC: 95%CI, 1.16-2.74, P=0.008). Moreover, compared with alleles, the risk of gastric cancer in T allele carriers increased by 1.69 times (95%CI, 1.16-2.44, P=0.006). Conclusion: miR-181b rs322931 polymorphism may be one of the susceptibility genes of gastric cancer in the Chinese Han nationality.
Practice and New Direction of Promoting the Construction of Managing System of Modern Hospital
Authors: Zhou Tao , Liu Xiaoxuan , Jia Wangtian , Yang Huijuan , Sun Zhijian , Ding Yufeng
Published: July 2021

If we want to enhance the medical level of modern hospital, we not only need to make the career morality and professional capability of the medical staff, but also require the perfection of the governance institution of hospital in accordance with the development of society. That said, the medical staff will provide the patients with the best service, which is significant to the development of hospital. In addition, every hospital should conduct deepening reform of public hospital comprehensively to respond to call of the government. And the hospital should also put forward professional and comprehensive managing system based on the concrete conditions of the hospital. That is how the hospital can serve the people better. That said, this article focuses on how to promote the system of managing the modern hospital.
Effect of Group Intervention Combined with Massage Nursing on Patients with Lymphedema
Authors: Qian Linlin
Published: July 2021

Objective: To evaluate and analyze the clinical effect of group intervention combined with massage nursing in patients with lymphedema. Methods: The time span of this study was selected from October 2017 to December 2020. A total of 496 patients with lymphedema after breast cancer surgery were included. They were divided into study group and control group according to the difference of nursing intervention scheme. The control group was given basic nursing, and the study group was given Satya group intervention combined with massage nursing. The indicators of the two groups were compared and analyzed. Results: Compared with the two groups at different time points, the study group had more advantages (P< 0.05). Compared with the recurrence rate of lymphedema in the two groups, the study group had more advantages (P< 0.05);Compared with the sads score and SES score after nursing intervention, the study group had more advantages (P< 0.05).Conclusion:  The clinical effect of group intervention combined with massage nursing in patients with lymphedema is significant, which can be promoted in all levels of medical institutions.
The Influence of Let-7b-5p Target Gene in Cholangiocarcinoma and its Bioinformatic Analysis
Authors: Zhang Xibing , Ran Jianghua , Liu Fang , Zhao Yingpeng , Hu Zongqiang
Published: July 2021

Objective: To analyze the biological functions and its clinical significance of let-7b-5p target gene in cholangiocarcinoma utilizing bioinformatics. Methods: The paper focuses on the let-7b-5p target gene, and predicts its biological functions as well as related signal pathways through GO biological function and KEGG signal pathway enrichment analysis. The STRING database and Cytoscape are used to construct a protein-protein interaction network to screen core genes. Results: The results of GO analysis showed that let-7b-5p target gene was mainly enriched in biological processes such as Small GTPase binding, Rho GTPase binding, and Rac GTPase binding. The results of KEGG analysis showed that let-7b-5p target gene was significantly enriched in key signaling pathways including Focal adhesion and ECM-receptor interaction. Through protein-protein interaction network and module analysis, CXCL8 and SDC2 were screened as the core site. Conclusion: let-7b-5p can participate in the regulation of biological functions of tumor cells in cholangiocarcinoma, suggesting that it may play an important role as a tumor suppressor gene and biomarker in the occurrence and development of cholangiocarcinoma, which provides new ideas for its diagnosis and treatment.
View on the Clinical Value of QRS-T Angle
Authors: Wang Danfeng , Jiang Leilei , Cai Zhen , Yang Yuqing , Li Jie
Published: July 2021

The QRS-T angle, as an index of non-invasive cardioelectric vector, is closely related to the change of heart structure and function. There are different methedologies to measure the QRS-T angle, which can be roughly dividedinto two types: plane angle and space angle. Studies show that the influence factors include two aspects of physiology and pathology of the angle, in pathological ways, the disease such as myocardial hypertrophy, myocardial ischemia, hypertension, ventricular arrhythmia has larger clinical significance. In recent years, the research on the risk stratification of the QRS-T angle on sudden death has made great progress, but there are still some disputes about whether the space angle can be replaced by the plane angle and the range of normal value and so on.
Prevention and Treatment of Deep Vein Thrombosis of the Lower Limbs in Patients with Complications after Orthopedic Trauma Surgery
Authors: Wang Ruiyao , Xiong Huimin , Qin Pengjun
Published: July 2021

Objective: To explore and analyze on how to prevent and treat deep vein thrombosis of the lower limbs in patients with complications after orthopedic trauma surgery. Methods: The research patients were selected from the cases of surgical treatment of orthopedic trauma in the hospital during the past two years, and a total of 58 patients were selected. The patients were randomly divided into two groups, with 29 patients in the control group treated with conventional clinical methods; and the other 29 patients were assigned to the experimental group, where targeted preventive and therapeutic measures were administered. During the research, the number of complications of postoperative deep vein thrombosis of the lower limbs and the corresponding treatment efficacy were compared between the two groups of patients. Results: According to the results of clinical experiments, the probability of patients in the experimental group suffering from deep vein thrombosis of the lower limbs after surgery was significantly lower than that of the control group (P<0.05); in addition, when complications of deep venous thrombosis of the lower limbs occurred, the treatment efficacy of the patients in the experimental group was 96.55%, and the treatment efficacy of the patients in the control group was 82.76%. There was a significant difference between the two groups (P<0.05). Conclusion: Through clinical experiments to study and analyze the prevention and treatment measures of deep vein thrombosis in patients with complications after orthopedic trauma surgery, this research proves that active and comprehensive preventive and treatment measures can effectively reduce the number of complications and improve surgery treatment efficacy.
A Brief Reading of the Republic of China Era Journal "Chinese Medicine Pillar Monthly"
Authors: Li Yanan , Li Yajun , Fu Xinjun
Published: July 2021

As one of the many traditional Chinese medicine journals in the Republic of China (ROC) era, the journal "Chinese Medicine Pillar Monthly" had been published for 11 consecutive years. It has rich content and covers a wide range of topics. It has important reference value for studying the direction of cultural development, political dynamics, and development trends of Chinese and Western medicine during the ROC era, and the journal was intended to spread the classics and clinical experience of traditional Chinese medicine, making it a medical treasure house. This paper mainly introduces the current status of the journal, the date of its inception, and its main content, features and contributions.