bluuebunny/crossref_metadata_2025 huggingface dataset:
USING SOCIAL MEDIA PLATFORMS IN EDUCATIONAL AND EDUCATIONAL ACTIVITIES: A HASHTAG REVIEW
Authors: KOÇ ERDEM
Published: June 2022

With the growing interest in online learning, the new understanding of education seeks ways to involve students in asynchronous knowledge content. Building on experiences with using hashtags to connect to social media platforms, the aim of this study is to explore the impact of hashtag use on student engagement in online discussions. In this study, it has been tried to reveal in which context students use hashtags, whether including hashtags in educational processes can contribute to the development of students and whether hashtags can support creating a learning community. For doing this, 36 randomly selected volunteer students studying in the 12th grade were conducted for focus group discussion. Quantitative measures were collected and analyzed to assess student interactions. Observations were made to understand the students' hashtag usage methods and to determine their interactions with each other. The content analysis about the obtained data was examined objectively with a systematic including the information obtained from the qualitative interviews. The hashtags used through the coding scheme were developed using the inductive and deductive approach. Considering the results of the study, it is understood that especially Twitter social platform hashtags give strong motivation to students in terms of educational activities and hashtags contributes to the ability to communicate synchronously and asynchronously with other individuals in the learning community; furthermore it is realised that hashtag is an application that should be supported since it has positive aspects such as creating an environment for students to express their ideas freely.
AN ANALYSIS ON EMOTIONAL DESIGN APPROACHES IN THE SAMPLE OF THE SEATING ELEMENT
Authors: GÜNDÜZ GÜLÇİN , CANPOLAT TÜLAY
Published: June 2022

Today, various emotional design approaches have been developed within the scope of emotion and design research. This study, deals with the concept of emotional design, the approaches of emotional design and product-user interaction made in this to date in terms of the seating element. The aim of the study is to analyze the emotional state that a furniture design that awakens the user at first glance. The interaction between furniture design and the user is presented through the Patrick W. Jordan’s pleasure approach and questionnaire method, in the emotional design literature. In this study, sample sets that will be analyzed by emotional responses are formed by considering the characteristics that differ in terms of practical function, aesthetic function and symbolic function. A total of 120 participants, 60 psychologists and 60 designers, were asked to evaluate 6 different seating element design by applying a questionnaire on the internet or one-on-one. As a result of the evaluation findings of the survey study, emotional values of two occupational groups were analyzed by comparing. In the conclusion, the contribution of the study to the field is to raise awareness of design approaches that focus on the emotional needs of users. In this context, it is revealed that emotional design approach can direct designers as a method in furniture design.
INVESTIGATION OF CHARACTER DESIGNS IN CONTEXT OF VISUAL IMPACT ITEM
Authors: KARAALİOĞLU SEVİM , SAYIN ZÜLFİKAR
Published: June 2022

Character designs can be used in animated cinema, comics, graphic novels, animation, advertisements, book illustrations, mascots, game graphics, toys, etc. It is one of the important graphic design applications encountered in many visual fields. Therefore, the designed characters must be visual indicators that are qualified, original, memorable, impressive and compatible with the content they reflect. In character development studies, the designed character's colors, anatomical features, gestures, facial expressions, clothes, characteristic qualities that distinguish him from those around him, etc. features are the influencing elements and principles that must be taken into account for the design to be distinctive. One of the important principles and elements of visual communication design, “impact” is one of the main guides used to strengthen the expression and make it distinctive, especially in character designs. It is very important to apply visual effects "effects" that will attract attention based on the prominent features of the characters, to create impacts on the audience and / or receptive masses. In this study, which was prepared with qualitative research methods, it is aimed to examine the visual character applications in the context of "effect", one of the graphic design principles and elements, to identify the problems and to develop suggestions for the solution of these problems. Therefore, following the use of the visual effect principle and element, which has an important place in the graphical character development process; The subject is defined and its importance is revealed, descriptive problems based on the form-content relationship encountered in design and practice are determined based on the applied characters, the causes of the identified problems are examined and suggestions are made for their solution. The analyzed characters consist of various animated movie images (figures) and concept designs. The investigations made, based on semiotic approaches such as "semantic", "syntactic" and "pragmatic" is carried out for visual effect applications in applied character descriptions.
Information retrieval and criticality in high-dimensional parity-time-symmetric systems
Authors: Qu Deng-Ke , Fan Yi , Xue Peng ,   Department of Physics, Southeast University, Nanjing 211189, China,   Beijing Computational Science Research Center, Beijing 100084, China,   The Army Infantry Academy of PLA, Shijiazhuang 050083, China
Published: June 2022

Recently, impressive progress has been made in the study of non-Hermitian systems with parity-time symmetry, such as observations of topological properties of physical systems and criticality at exceptional points. A crucial aspect of parity-time symmetric nonunitary dynamics is the information flow between the system and the environment. In this paper, we use the physical quantity, distinguishability between quantum states, to uniformly quantify the information flow between low-dimensional and high-dimensional parity-time symmetric non-Hermitian systems and environments. The numerical results show that the oscillation of quantum state distinguishability and complete information retrieval and can be obtained in the parity-time-unbroken phase. However, the information decays exponentially in the parity-time-broken phase. The exceptional point marks the criticality between reversibility and irreversibility of information flow, and the distinguishability between quantum states exhibits the behavior of power-law decay. Understanding these unique phenomena in nonunitary quantum dynamics provides an important perspective for the study of open quantum systems and contributes to their application in quantum information.
Homotopic contralesional excitation suppresses spontaneous circuit repair and global network reconnections following ischemic stroke
Authors: Bice Annie R , Xiao Qingli , Kong Justin , Yan Ping , Rosenthal Zachary Pollack , Kraft Andrew W , Smith Karen P , Wieloch Tadeusz , Lee Jin-Moo , Culver Joseph P , Bauer Adam Q
Published: June 2022

Understanding circuit-level manipulations that affect the brain’s capacity for plasticity will inform the design of targeted interventions that enhance recovery after stroke. Following stroke, increased contralesional activity (e.g. use of the unaffected limb) can negatively influence recovery, but it is unknown which specific neural connections exert this influence, and to what extent increased contralesional activity affects systems- and molecular-level biomarkers of recovery. Here, we combine optogenetic photostimulation with optical intrinsic signal imaging to examine how contralesional excitatory activity affects cortical remodeling after stroke in mice. Following photothrombosis of left primary somatosensory forepaw (S1FP) cortex, mice either recovered spontaneously or received chronic optogenetic excitation of right S1FP over the course of 4 weeks. Contralesional excitation suppressed perilesional S1FP remapping and was associated with abnormal patterns of stimulus-evoked activity in the unaffected limb. This maneuver also prevented the restoration of resting-state functional connectivity (RSFC) within the S1FP network, RSFC in several networks functionally distinct from somatomotor regions, and resulted in persistent limb-use asymmetry. In stimulated mice, perilesional tissue exhibited transcriptional changes in several genes relevant for recovery. Our results suggest that contralesional excitation impedes local and global circuit reconnection through suppression of cortical activity and several neuroplasticity-related genes after stroke, and highlight the importance of site selection for targeted therapeutic interventions after focal ischemia.
The role of surface adhesion on the macroscopic wrinkling of biofilms
Authors: Geisel Steffen , Secchi Eleonora , Vermant Jan
Published: June 2022

Biofilms, bacterial communities of cells encased by a self-produced matrix, exhibit a variety of three-dimensional structures. Specifically, channel networks formed within the bulk of the biofilm have been identified to play an important role in the colonies' viability by promoting the transport of nutrients and chemicals. Here, we study channel formation and focus on the role of the adhesion of the biofilm matrix to the substrate in Pseudomonas aeruginosa biofilms grown under constant flow in microfluidic channels. We perform phase contrast and confocal laser scanning microscopy to examine the development of the biofilm structure as a function of the substrates' surface energy. The formation of the wrinkles and folds is triggered by a mechanical buckling instability, controlled by biofilm growth rate and the film’s adhesion to the substrate. The three-dimensional folding gives rise to hollow channels that rapidly increase the effective volume occupied by the biofilm and facilitate bacterial movement inside them. The experiments and analysis on mechanical instabilities for the relevant case of a bacterial biofilm grown during flow enable us to predict and control the biofilm morphology.
Host chitinase 3-like-1 is a universal therapeutic target for SARS-CoV-2 viral variants in COVID-19
Authors: Kamle Suchitra , Ma Bing , Lee Chang Min , Schor Gail , Zhou Yang , Lee Chun Geun , Elias Jack A
Published: June 2022

Coronavirus disease 2019 (COVID-19) is the disease caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2; SC2), which has caused a worldwide pandemic with striking morbidity and mortality. Evaluation of SC2 strains demonstrated impressive genetic variability, and many of these viral variants are now defined as variants of concern (VOC) that cause enhanced transmissibility, decreased susceptibility to antibody neutralization or therapeutics, and/or the ability to induce severe disease. Currently, the delta (δ) and omicron (ο) variants are particularly problematic based on their impressive and unprecedented transmissibility and ability to cause breakthrough infections. The delta variant also accumulates at high concentrations in host tissues and has caused waves of lethal disease. Because studies from our laboratory have demonstrated that chitinase 3-like-1 (CHI3L1) stimulates ACE2 and Spike (S) priming proteases that mediate SC2 infection, studies were undertaken to determine if interventions that target CHI3L1 are effective inhibitors of SC2 viral variant infection. Here, we demonstrate that CHI3L1 augments epithelial cell infection by pseudoviruses that express the alpha, beta, gamma, delta, or omicron S proteins and that the CHI3L1 inhibitors anti-CHI3L1 and kasugamycin inhibit epithelial cell infection by these VOC pseudovirus moieties. Thus, CHI3L1 is a universal, VOC-independent therapeutic target in COVID-19.
Remote sensing techniques for automated marine mammals detection: a review of methods and current challenges
Authors: Rodofili Esteban N. , Lecours Vincent , LaRue Michelle
Published: June 2022

Marine mammals are under pressure from multiple threats, such as global climate change, bycatch, and vessel collisions. In this context, more frequent and spatially extensive surveys for abundance and distribution studies are necessary to inform conservation efforts. Marine mammal surveys have been performed visually from land, ships, and aircraft. These methods can be costly, logistically challenging in remote locations, dangerous to researchers, and disturbing to the animals. The growing use of imagery from satellite and unoccupied aerial systems (UAS) can help address some of these challenges, complementing crewed surveys and allowing for more frequent and evenly distributed surveys, especially for remote locations. However, manual counts in satellite and UAS imagery remain time and labor intensive, but the automation of image analyses offers promising solutions. Here, we reviewed the literature for automated methods applied to detect marine mammals in satellite and UAS imagery. The performance of studies is quantitatively compared with metrics that evaluate false positives and false negatives from automated detection against manual counts of animals, which allows for a better assessment of the impact of miscounts in conservation contexts. In general, methods that relied solely on statistical differences in the spectral responses of animals and their surroundings performed worse than studies that used convolutional neural networks (CNN). Despite mixed results, CNN showed promise, and its use and evaluation should continue. Overall, while automation can reduce time and labor, more research is needed to improve the accuracy of automated counts. With the current state of knowledge, it is best to use semi-automated approaches that involve user revision of the output. These approaches currently enable the best tradeoff between time effort and detection accuracy. Based on our analysis, we identified thermal infrared UAS imagery as a future research avenue for marine mammal detection and also recommend the further exploration of object-based image analysis (OBIA). Our analysis also showed that past studies have focused on the automated detection of baleen whales and pinnipeds and that there is a gap in studies looking at toothed whales, polar bears, sirenians, and mustelids.
Teaching Deficiencies of Teacher-Education Graduates of JRMSU-TC Based on the DepEd Criteria for Hiring Teachers
Authors: Liboon Jr. Alfredo , Rodriguez Elmira
Published: June 2022

The success of any educational system greatly relies on the competence of its teachers. That is why the Department of Education (DepEd) had set criteria in hiring competent and skillful teachers. The study aimed to identify the deficiencies of the JRMSU-TC applicants based on the DepEd criteria for hiring teachers. This further determined the percentage of disparity which item in the DepEd criteria the applicants deficit most and described whether they are above or below the minimum passing rate set by the DepEd. The researchers retrieved the Registry of Qualified Applicants (RQA) from the DepEd Office- Zamboanga Del Norte as instruments of the study and utilized descriptive evaluative design to measure the inadequacies of the applicants based on the DepEd criteria. Results revealed that the JRMSU-TC applicants highly deficit in teaching experience and English proficiency. Furthermore, the applicants are slightly below the DepEd minimum passing points. The results suggest that graduates should venture for the improvement of teaching competence and professional preparations. Also, the school needs to improve its instruction and assessment on the fundamental and major English subjects.
Internationalization at the College of Business, JBLFMU-Molo Through Collaborations: Benefits, Challenges, and Prospects
Authors: Alimen Rolando , Pador Glenito
Published: June 2022

Internationalization is a challenge that the maritime university (JBLFMU-Molo) faces against a domestic as well as global backdrop. In response to this challenge, this study discussed the merits of educational reform anchored on a distinct orientation of internationalization. Thus, the College of Business of JBLFMU-Molo started the different multinational activities that focus on the need of the maritime university to integrate international dimension into maritime business-related education. The researchers employed qualitative method through interview utilizing an open-ended instrument as a mode of data collection. Findings reveal that the flexibility of students and exposure to the international curriculum were the major important elements achieved through internationalization. Students who were exposed to international collaboration adjust to international culture and communication. Opportunities and prospects of internationalization lead to more exposure to international trends, issues in maritime and business education, linkages in the business and education aspects, quality assurance, accreditation, and distance education. Through internationalization, educational reforms will be enhanced at the college. The study recommends that the administration of JBLFMU-Molo will be used as basis to continuously build closer linkages and increase more collaboration in student mobility, memoranda of agreement, and other programs to improve the overall quality of maritime and business-related education in the ASEAN region.
Lemierre’s Syndrome Presenting Section with Pleural Effusion
Authors: Barui Hrishikesh , Das Anirban , Goswami Preetam , Biswas Rathindra Nath
Published: June 2022

Lemierre’s syndrome is a condition characterised by septic thrombophlebitis of internal jugular vein following an oropharyngeal infection along with septic embolisation to other organs mainly lungs. This report is about a 14-year-old girl who presented with complaint of high-grade fever, progressive shortness of breath and painful swelling of throat for seven days. Chest radiograph showed left hemithorax homogenous opacity with contralateral mediastinal shift. Complete haemogram and other blood investigations revealed neutrophilic leucocytosis and raised C-reactive protein. Gram stain and aerobic culture of sputum, pleural fluid and blood were inconclusive. As there was no relief of symptoms even after empirical treatment with antibiotics, Contrast Enhanced Computed Tomography (CECT) scan of neck and thorax was done, and it showed bilateral ectatic internal jugular veins with intravascular thrombus and consolidation of left lung with ipsilateral pleural effusion. Ultrasonography of neck confirmed the presence of thrombus in internal jugular vein on both sides. She was started on intravenous clindamycin and subcutaneous anticoagulants. Gradually the symptoms of the patient resolved. To conclude with, despite being called a “forgotten disease”, Lemierre’s syndrome requires strong clinical suspicion and prompt management to prevent mortality.
Comparative Evaluation of the Effect of Clonidine and Dexmedetomidine as Adjuncts to Lignocaine in Intravenous Regional Anaesthesia in Forearm and Hand SurgeriesA Randomised Clinical Study
Authors: Krishnendu S , Chandak Aruna , Chandak Vijay , Verma Neeta , Ninave Sanjot , Chakole Vivek , Taksande Karuna
Published: June 2022

Introduction: Intravenous regional anaesthesia for forearm and hand surgeries, which is one of the safe, cost-effective and rapid onset anaesthesia is less popular nowadays, because of its lesser postoperative analgaesia and tourniquet pain. Aim: To compare dexmedetomidine and clonidine as an adjuvant to 0.5% lignocaine to study block characteristics, tourniquet pain and postoperative analgaesia in forearm and hand surgeries. Materials and Methods: This randomised clinical trial was conducted in Acharya Vinoba Bhave Rural Hospital (Tertiary Care Hospital), Wardha, Maharashtra, India, from September 2019 to September 2021 on 70 patients posted for forearm and hand surgeries. The patients were divided into two groups of 35 each. Group C received clonidine 1 mcg /kg with 40 mL of 0.5% lignocaine preservative free. Group D received dexmedetomidine 1 mcg /kg with 40 mL of 0.5% lignocaine preservative free. Independent samples t-test was used for evaluation of demographic data, haemodynamic data, block characteristics, duration of surgery and tourniquet, onset of tourniquet pain, duration of analgaesia and intraoperative and postoperative analgesic requirement. Results: Onset of sensory and motor block was faster with dexmedetomidine group (1.60±0.60 min and 2.77±0.81 min) when compared to clonidine group (3.57±0.74 min and 6.40±1.26 min). Duration of analgaesia was significantly longer in group D (345.23±44.52 min) compared to group C (205.14±37.76 min), sensory and motor regression was delayed with group D (7.69±0.72 min) as compared to group C (6.40±0.85 min). There was no significant adverse effect noted in both the groups. Conclusion: Dexmedetomidine is an excellent adjuvant when added to lignocaine for Intravenous Regional Anaesthesia (IVRA) in terms of block quality, postoperative analgaesia, and adverse effects.
Trend and Relationship of Market Arrivals and Prices of Major Oilseeds in Krishi Upaj Mandies in Chhattisgarh
Authors: Patel Pradip Kumar , Jain Bhag Chandra , Wasnik Sumit B. , Pandey Sneha , Patel Mamta
Published: June 2022

Aim: To analysis the trend pattern and correlation of market arrivals and prices of major oilseeds in Krishi Upaj Mandies of Chhattisgarh.

Study Design:  The study was based on secondary data. The linear model for trend analysis and Karl Pearson’s correlation coefficient for relationship between arrivals and prices were used in the study.

Place and Duration of Study: The study was conducted in four Krishi Upaj Mandies of Chhattisgarh. The monthly wise time series data from period of 2006-07 to 2020-21 were considered for study.

Methodology: Four Krishi Upaj Mandies viz., Rajnandgaon, Bemetara, Pathalgaon and Ramanujganj were selected according to collectively maximum arrivals of major oilseeds in Chhattisgarh. 

Results: The trend of arrivals of soybean in Rajnandgaon mandi was observed increasing trend over the year. Whereas, Bemetara mandi was shows negative decreasing trend. In case of groundnut positive but least trend were observed in arrivals of all selected mandies. In case of mustard least trend of arrivals was observed in Bemetara and Pathalgaon mandies. While significant increasing trend were noticed in Rajnandgaon and Ramanujganj mandies. The trends of prices of major oilseeds were found to be positively increasing in all selected mandies. The correlation coefficient of arrivals and prices of major oilseeds were positive and significant in all selected mandies except Bemetara and Rajnandgaon mandies. In Bemetara mandi approx no-correlation was found between arrivals and prices of soybean. Whereas Rajnandgaon mandi of mustard crop was seen positive but not significant of any level.

Conclusion: The study concludes that the trends of arrivals of major oilseeds in various Mandies were estimated least over the years. The Majorities of Krishi Upaj Mandies were found to be positive and significant correlation between arrivals and prices. It was indicates that the variables of arrivals and prices were significantly associated with each other over the time.
Phylogenetic Identification and Some Physiological Properties of Lactic Acid Bacteria Isolated from the Oral Cavities of Some Selected Students from University of Ibadan, Nigeria
Authors: Omeonu Francis Chukwumma , Onilude Anthony Abiodun , Azuh Victor Okechukwu , Laba Sunday Ademola
Published: June 2022

Lactic Acid Bacteria (LAB) have been reported to be a component of the human and animal microbiome, functioning as probiotics. Their capacity to stick to the epithelial or mucosal surface is mostly dependent on receptor specific binding, charge, and hydrophobicity interaction. Much work have been done on the hydrophobicity and some physiological properties of LAB from different sources but there is a dearth of knowledge on those of the oral cavity, hence this study.

Oral samples were collected from respondents from different areas of the University Of Ibadan with sterile swab stick and were brought to the microbiology laboratory of the University of Ibadan for analysis. The isolates were subjected to morphological, biochemical, molecular and physiological tests using standard procedures.

In this study, nine colonies of LAB were isolated and characterized from oral samples of respondents from the University of Ibadan. They were identified as, Pedicoccus acidilactici, Leuconostoc lactis, Leuconostoc mesenteroides, Lactobacillus acidophilus, Lactobacillus reuteri, Lactobacillus brevis, Lactobacillus fermentum, Lactobacillus plantarium, and Lactobacillus casei. All the isolates inhibited the growth of the four pathogens used, survived at 4% concentration of NaCl, MgSO4, KNO3, NaNO3, MnSO4 and 3% bile salts used. They exhibited low surface hydrophobicity, survived in the acidic and temperatures of the media used.
Study of Cognitive and Behavioral Impacts of Idiopathic Epilepsy and Antiepileptic Drugs (AEDs) in Children and Adolescents
Authors: Aboeisa Mohamed Ibrahim , Seleem Mohammad Abdel Hakeem , Gohary Tarek Mohamed El , Shahawy Azza Kamal Al
Published: June 2022

Background: Epilepsy is a common neurological condition that can have a detrimental impact on social, emotional, and cognitive functioning. Psychiatric and cognitive problems in children with epilepsy and antiepileptic drugs can affect quality of life. Long-term follow-up studies reveal that epilepsy that develops in childhood is more common than epilepsy that develops later in life. Has a marked impact on adult life even when the epilepsy is not complicated by intellectual disability or other neurological impairments. The aim of this study was to study cognitive and behavioral impacts of idiopathic epilepsy and antiepileptic drugs in children and adolescents compared to normal ones.

Methods: This prospective, case control study was conducted on 60 children or adolescents suffering from idiopathic epilepsy aged 6-16 years. Children were classified into four equal groups and were examined after 6 months from diagnosis: Group A subjected to valproic acid at a dose of 10-60 mg/kg/day, group B subjected to Carbamazepine at a dose of 10-30 mg/kg/day, group C subjected to levetiracetam at a dose of 10-60 mg/kg/day and group D subjected to Oxcarbazepine at a dose of 20-30 mg/kg/day. Thirty healthy children or adolescents of matched age and sex served as a control group who attended Pediatric General Outpatient Clinic of Tanta University Hospitals. The following was done to all of the patients: full history taking, complete physical examination, routine laboratory investigations, electroencephalography, brain magnetic resonance imaging, specific tests for behavior and executive functions including the Child Behavior Checklist – school age, Stanford-Binet Intelligence Scales (fifth version), Wisconsin Card Sorting Test and Continuous Performance Test. Thirty healthy children or adolescents of matched age and sex served as a control group.

Results: Children with epilepsy who were treated with AEDs showed higher behavioral problems scales, lower mean IQ and lower executive functions as compared to controls. LEV and VPA had a more negative effect on behavior than CBZ and OXC while VPA and CBZ had a more negative effect on mean IQ and executive functions than LEV and OXC.

Conclusion: Antiepileptic drugs (AEDs) may be one of the causes of epilepsy-related cognitive and behavioral issues in children.
An In-silico Study Showing Potentials of Selected Anthocyanin Derivatives against Uropathogenic E. coli Adhesin Protein
Authors: Chowdhury Abhishek , Choudhury Manabendra Dutta , Laskar Monjur Ahmed
Published: June 2022

Urinary tract infections (UTI) caused primarily by uropathogenic Escherichia coli (UPEC) are indeed an extremely contagious disease that affects people all over the world. FimH is a major virulence component in UTI pathogenesis, and inhibiting FimH function can be an efficient means to disarm UPEC bacteria, as well as a crucial target in the development of non-antibiotic mediated UTI treatment options. The goal of this study was to identify anthocyanins in plant parts and assess

their pharmacological characteristics. A computational methodology was used to predict the pharmacological characteristics of such substances. Compounds with pharmacophores comparable to those of known fimH inhibitors were chosen. Following that, additional research was carried out to assess their drug similarity, inhibitory potential, and IC50 values. Thus, the present study reports few novel fimH inhibitors derived from the selected plant’s phytochemicals, and is significant owing to their therapeutic implication as a non-antibiotic mediated therapy for UTI.
Research on Acupoint Tapping Therapies Proliferating around the World
Authors:   Santa Rosa, CA, Freedom John , Hux Marg ,   Burlington, Ontario, Canada, Warner Jan ,   Veteran Affairs Medical Center, Cleveland, Ohio USA
Published: June 2022

Background: The evidence base for acupoint tapping including Emotional Freedom Techniques (EFT) includes over 120 clinical trials showing relatively rapid and durable improvements for a range of psychological and physical conditions. It supports the premise that tapping is an active ingredient and shows associated physiologic changes. This evidence is based in standard Western literature databases such as EBSCO and overwhelmingly in English. Objective: The current report explores international and regional research on EFT not previously known in the Western literature evidence base. Methods and Results: A search of ResearchGate found 86 research studies on acupoint tapping not identified in standard Western databases. A systematic search of 21 databases using the EBSCO search engine yielded an additional five previously unknown papers for a total of 91 research studies. These studies were published in regional and international journals (71% in Indonesia) with most published primarily in languages other than English (81% had only title and/or abstract available in English). EFT was used in 47% of the studies, and the remaining studies used “Spiritual EFT” (SEFT), a variation developed in Indonesia combining tapping with spiritual affirmations from the Quran. The majority (84%) were single group or comparative clinical trials and 5% were literature reviews. The target issue included a range of psychological or medical conditions such as anxiety (29%), depression (15%), and hypertension (11%). In a further step, the potential magnitude of this additional research base was explored using Google Scholar. Challenges include inconsistent quality of translations, limited search capabilities of Google Scholar, lack of full text translated into English, and reasons why this literature is not found in the major databases. Conclusion: This review identified a large number of studies that had been “invisible” in the West due to their having been published in non-English-language journals. They demonstrate growing interest in EFT throughout the world. In comparison with English-language EFT databases, these studies tend to be more frequently performed in treatment settings such as hospitals, clinics, and universities, and they often address medical diagnoses such as diabetes, hypertension, and pain as well as psychological conditions. In addition, they apply EFT with populations rarely focused upon in Western EFT studies, such as prisoners, addicts, cancer patients, and diabetics. Finally, these studies provide a valuable perspective on how acupoint tapping is being used around the world in real-life settings. Keywords: tapping, EFT, Emotional Freedom Techniques, energy psychology, acupoint tapping, Spiritual EFT
Crise Global Coronavírus: monitoramento e impactos
Authors: Diniz Michely Correia , Martins Marlos Gomes , Xavier Keyla Vitória Marques , Da Silva Monique Ayala Araújo , Santos Erick de Aquino
Published: June 2022

Em 11 de março de 2020, a Organização Mundial de Saúde declarou que o mundo estava sendo alvo de uma pandemia devido ao novo coronavírus. O objetivo deste trabalho foi analisar o panorama das pesquisas e das políticas públicas focadas na COVID-19, mapeando o desenvolvimento de tecnologias relacionadas ao tema. A pesquisa teve caráter descritivo e exploratório, ao analisar informações de forma abrangente a partir de referências bibliográficas, com enfoque no repositório PubMed. A prospecção tecnológica quantitativa sobre os coronavírus, através de 06 bancos de patentes, vem a complementar essa análise qualitativa.  Com a crise global causada pela COVID-19, a produção de conhecimento e plataformas digitais foi extremamente acelerada num curto espaço de tempo. Praticamente todos os países foram afetados pela pandemia, e aqueles que entenderam a gravidade da situação mais rapidamente, e implementaram políticas e tecnologias assertivas puderam mitigar os impactos de curto prazo, principalmente no que diz respeito à preservação de vidas.
Coronavírus no Processo de Impactação Científica Global
Authors: Tatum Carlos Tadeu Santana , Tatum Letícia-Maria Macedo , Russo Suzana Leitão , Oliveira Sérgio Silva , Camargo Maria Emília , Carvalho Tecia Vieira , Castro Francisco Edivaldo Brito de
Published: June 2022

O mundo foi acometido por uma doença altamente contagiosa que veio a público em dezembro de 2019, chamada de COVID-19, originada na China, pertencente à família do coronavírus. Por isso, o objetivo deste estudo é avaliar o impacto dessa doença na produção científica. Este trabalho trata-se de uma pesquisa exploratória, com busca de documentos científicos na base de dados Lens.org, considerando-se o período de 1951 até 7 de março de 2020 e utilizando-se como palavra-chave “coronavirus” com o boleano OR para COVID-19. Os resultados mostraram uma movimentação global científica através do crescimento do número de publicações, participação efetiva de países, institutos apoiadores de pesquisas, editoras, todos juntos somando esforços em busca de soluções ao controle da pandemia. Dessa forma, espera-se que este estudo possa servir de apoio a pesquisas futuras, agilizando as buscas científicas no combate ao coronavírus, especificamente ao COVID-19.
Coronavírus (SARS-COV-2) e COVID-19: mapeamento de testes clínicos
Authors: Quintella Cristina M. , Quintella Heitor da Mata , Palma Giovanni Batista , Silva Sávio Carlos Rodrigues da , Silva Gustavo Henrique Ramos
Published: June 2022

Os testes clínicos (TRL5 a TRL9) do novo Coronavírus foram mapeados para se obter o estado da arte atual. Esse mapeamento foi feito na base internacional da Organização Mundial da Saúde e complementado em bases nacionais. Após triagem, foram obtidos 661 documentos para serem analisados. Descobriu-se que há estudos em 25 países, apesar de a maioria desses estudos estar concentrada na China. As empresas financiam menos de 6% dos estudos e grande parte deles está na Fase Zero (fase pré-clínica), apenas 2% estão já em execução e nenhum trouxe resultados ainda. Seus objetivos primários são terapias, no entanto, uma grande maioria se dedica à medicina chinesa e apenas 245 estão focados em tecnologias transnacionais de antivirais, imunoterapia e em vacinas. Os compostos ativos são de ampla gama, havendo concentração em hidroxicloroquina/cloroquina (31) e em células-tronco (22). As pesquisas focam especialmente em adolescentes e em adultos jovens, deixando descobertos os estudos sobre pacientes longevos.
Enfrentamento à Covid-19: um mapeamento das patentes de ventiladores mecânicos
Authors: Silva Marina Bezerra da , Freitas Robson Almeida Borges de , Cruz Cleide Ane Barbosa da , Xavier Ana Claudia Galvão , Camargo Maria Emília , Oliveira Junior Antônio Martins de , Paixão Ana Eleonora Almeida , Fabris Jonas Pedro
Published: June 2022

Com o avanço dos casos de Covid-19 no mundo, muitos equipamentos tornaram-se imprescindíveis para o combate e o controle da doença, sendo um deles o ventilador mecânico. Por isso, este artigo tem o objetivo de apresentar a produção de patentes relacionadas ao suporte ventilatório pulmonar. Em relação à metodologia, utilizou-se a plataforma Lens.org para o levantamento e a análise dos dados, usando-se os termos de busca: medical ventilator, mechanical ventilator, lung e ventilation. Foram analisados 107 documentos dessas patentes, concedidas no período de 1982 a 2020, sendo que os Estados Unidos é o maior depositante de patentes. Não foram identificadas patentes brasileiras na plataforma Lens.org. Dessa forma, entende-se a necessidade de expandir o desenvolvimento de pesquisas sobre esse equipamento, incentivando-se empresas e instituições de ciência e de tecnologia a fazerem parcerias para ampliar estudos sobre suporte ventilatório pulmonar que se tornou aliado no controle da Covid-19 em pacientes que apresentam insuficiência respiratória.
Prospecção Científica e Tecnológica acerca da Covid-19: análise das abordagens terapêuticas farmacológicas inseridas no contexto pandêmico
Authors: Pereira de Oliveira Antonio Carlos , Damasceno Fontenele Darllan , Costa Sousa Gabrielle , Sousa de Pinho Samara , Carvalho da Silva Katriane , De Oliveira Ana Patrícia , Duarte Nicolau Lucas Antonio , Rolim Medeiros Jand Venes
Published: June 2022

O SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) é um vírus com alta capacidade de disseminação que pode causar uma forte pneumonia. Como ainda não há um tratamento efetivo recomendado pela Organização Mundial de Saúde (OMS), o presente estudo realizou uma prospecção científica e tecnológica, destacando possíveis tratamentos que possam ser eficazes no combate à Covid-19. A coleta de artigos e de patentes sobre o SARS-CoV-2 foi realizada por meio de palavras-chave nos bancos Web of Science, SciELO (Scientific Electronic Library Online), PubMed (Public MEDLINE) e Scopus e nas bases de patentes World Intellectual Property Organization (WIPO), United States Patent and Trademark Office (USPTO), Instituto Nacional de Propriedade Industrial (INPI) e European Patent Office (EPO). Na prospecção, foram contabilizados 81 artigos acerca do tratamento e nenhuma patente depositada nos bancos supracitados, evidenciando forte procura para o tratamento, apesar de não apresentar registro de patentes para o produto ou para o processo.
Revisão Sistemática da Literatura de Competências Profissionais para Inovação: uma análise dos últimos 10 anos
Authors: Oliveira Silva Pedro Henrique , Bittencourt Ibsen Mateus
Published: June 2022

As competências desempenham papel central nos sistemas de inovação e na dinâmica do crescimento econômico, tanto que políticas de inovação tratam do desenvolvimento de competências como questão estratégica. A capacidade inovadora, apesar de ser uma habilidade individual, aplicada em conjunto, transforma as empresas e a sociedade em que trabalham mais competitivas. O presente estudo é caracterizado por uma revisão sistemática da literatura que objetiva identificar quais competências são necessárias para que o trabalhador desenvolva alguma inovação. A pesquisa realizada se baseou em 130 estudos para descobrir quais competências são necessárias para que um trabalhador desenvolva alguma inovação. Os resultados indicam não existir um consenso sobre quais seriam de fato as competências profissionais para inovar, considerando que a própria competência, assim como a própria inovação são fenômenos altamente contextuais e que há lacunas na literatura sobre como um indivíduo pode aprendê-las dentro de um processo de ensino-aprendizagem.
Monitoramento Tecnológico da Planta Cagaita (Eugenia dysenterica) e Aplicações Biotecnológicas Potenciais
Authors: Rodrigues-Silva Paolo Lucas , Amorim Gabriella Cavalcante , Andrade Isadora Emanoela Pereira Costa , Cunha Victor Albuquerque , Figueiredo Luciana Harumi Morimoto , Grossi-de-Sa Maria Fatima
Published: June 2022

O bioma Cerrado ocupa cerca de 23% da área brasileira e é considerado o segundo maior bioma do Brasil. Possui cerca de 4.800 espécies endêmicas, incluindo a espécie frutífera Eugenia dysenterica DC. (cagaita). Rica em nutrientes, esta espécie possui potencial econômico no Brasil por possuir ações diretamente relacionadas à saúde humana. O presente estudo realizou o monitoramento tecnológico dos conhecimentos e das tecnologias geradas, utilizando a espécie E. dysenterica, no período de 2009-2019. Os dados demostraram que durante esse período foram encontrados para esta espécie 77 dissertações, 21 teses, 97 artigos científicos e duas patentes depositadas. Uma análise mais detalhada demonstrou que parte do conhecimento e das tecnologias geradas está concentrada na área de biotecnologia ambiental (35,9%), seguida pela biotecnologia industrial (28,3%), biotecnologia da saúde (22,8%) e biotecnologia vegetal (13%). Assim, o artigo analisa e discute o potencial a ser explorado em relação à E. dysenterica para o desenvolvimento de produtos biotecnológicos de interesse comercial.
Estudo Prospectivo das Tecnologias Utilizadas para Redução das Emissões de Poluentes Causadas pelos Veículos a Diesel
Authors: Da Silva Humbervânia Reis Gonçalves , Quintella Cristina M.
Published: June 2022

O óleo diesel quando utilizado em motores pode gerar formação de depósitos de combustível insolúvel nos injetores, esse depósito gera redução na economia do combustível e contribui para gerar emissões de vários de tipos de poluentes. Assim, se faz necessário o mapeamento das tecnologias já existentes que são utilizadas para reduzir as emissões desses poluentes com o objetivo de orientar e de estruturar a pesquisa quanto ao desenvolvimento de novos métodos. A estratégia de busca consistiu em uma combinação, de códigos de Classificação Internacional de Patentes (CIP), F01N-003 OR F01N-003/18) AND (C10L-001 OR C10L-001/24 OR C10L-001/24. Sessenta e seis documentos de patentes selecionados foram lidos e analisados. Foi possível observar a existência de maior proteção no ano de 2002 e uma superioridade de registros nos EUA. Algumas tendências tecnológicas estão relacionadas à tecnologia ambiental, referem-se a dispositivos e equipamentos, mas apenas uma faz referência ao controle das emissões de compostos sulfurados.
Prospecção sobre Armadilhas para Mosquitos Aedes Aegypti e Tecnologias Relacionadas
Authors: Gois Antonio Wanderson Vieira , Rocha Angela Machado , Lopes Alan Nascimento
Published: June 2022

O mosquito Aedes aegypti gera diversos malefícios à humanidade há séculos, essencialmente por ser vetor de muitas doenças. Devido às transformações socioambientais que o planeta vem sofrendo, os prejuízos por ele causados têm se agravado bastante. Nesse aspecto, a análise prospectiva pode mapear o cenário das inovações e nortear as estratégias de desenvolvimento tecnológico para controle do mosquito. Destarte, este estudo descritivo baseia-se em pesquisa exploratória patentária realizada por meio da base Derwent Innovation Index, com abordagens qualiquantitativas sobre armadilhas e tecnologias correlatas para controle do mosquito Aedes aegypti publicadas entre 2000 e 2020. As tecnologias analisadas apontam, sobretudo, estratégias para eliminar esses insetos, ao passo que, para monitorá-los, é necessário aplicar mais investimentos no desenvolvimento de ovitrampas e atrativos mais potentes e menos nocivos ambientalmente. Foram identificadas 57 famílias de patentes sobre as tecnologias estudadas, com tendência estável e ligeiramente decrescente no número de depósitos, sendo o Brasil o maior depositante, e os EUA o principal foco dos depósitos.
Prospecção Tecnológica em Núcleos de Inovação Tecnológica do Estado do Rio de Janeiro
Authors: Alcantara Maísa Magalhães , Borschiver Suzana , Alencar Maria Simone de Menezes
Published: June 2022

O objetivo geral deste artigo é entender o gerenciamento de recursos e know how que têm tornado viáveis estudos de prospecção tecnológica nos NITs do Estado do Rio de Janeiro. Desse modo, foi realizada uma análise acerca da criação de um ambiente inovador no Brasil e sobre a criação dos NITs, os quais possuem como uma de suas competências a realização de estudos de prospecção tecnológica. Para embasar a pesquisa, foram realizados estudos de caso a partir de uma seleção de NITs do Estado do Rio de Janeiro, esses NITs alegaram realizar estudos de prospecção tecnológica para o FORMICT ano base 2017 e disseram ser integrantes da REPICT. Percebeu-se que são poucos os estudos de prospecção tecnológica mais elaborados, já que os NITs selecionados possuem poucos profissionais na equipe dedicados a esses estudos. Mesmo com poucos estudos, resultados benéficos têm sido percebidos pelos NITs estudados ao efetuarem os estudos de prospecção tecnológica.
Prospecção Tecnológica sobre Equipamentos para Administração Intramamária de Ozônio em Vacas Leiteiras
Authors: Fuentes Arévalo Esther Abihail , Almeida Cláudia Beatriz , Escodro Pierre Barnabé
Published: June 2022

A administração de antibióticos intramamários é o método mais utilizado no tratamento da mastite. No entanto, esse tratamento está desenvolvendo resistência microbiana. Com o uso de tratamentos de ozônio, é alcançada uma reação favorável na doença. Com o objetivo de avaliar o panorama do estado atual e a evolução de tecnologias associadas à ozônioterapia na mastite, foi realizada uma prospecção tecnológica, por meio de busca de patentes depositadas internacionalmente, para a busca foi utilizado o banco europeu de patentes (EPO-Espacenet®), fazendo uso de palavras-chave e códigos IPC, e combinações entre eles. Como resultados, foram encontradas 56 patentes relacionadas ao escopo desta pesquisa, que mostraram que, em sua maioria, a inovação tem sido realizada em acessórios para aplicação de medicamentos intramamários, pelos países dos EUA e Japão. Além de perceber que nas últimas décadas, houve uma queda em termos de depósito de patentes e, portanto, em inovação de tecnologias.
O Desempenho e as Tendências das Patentes Verdes na Amazônia Legal
Authors: Fanhaimpork Dinorvan , Nacimento Diemerson de Souza , Melo Daniel Reis Armond de
Published: June 2022

O estudo pretende identificar as tecnologias verdes que estão sendo protegidas e as respectivas áreas de interesse das universidades, instituições de pesquisa, empresas e inventores no âmbito da Amazônia Legal. Este estudo descritivo e quantitativo possibilitou a identificação das tendências de tecnologias verdes protegidas na região amazônica por meio do mapeamento dos depósitos junto ao Instituto Nacional da Propriedade Industrial (INPI) entre abril de 2012 e dezembro de 2020. O estudo demonstrou poucos depósitos de patentes verdes, sendo que as pessoas físicas são as principais depositantes. A técnica da redação clara e objetiva é uma dificuldade a ser superada enquanto as tecnologias relacionadas ao gerenciamento de resíduos são predominantes. O resultado demonstra que a região amazônica não se apropriou desse mecanismo de forma a aproveitar seu potencial frente ao desenvolvimento sustentável. As políticas instituídas e os mecanismos de incentivos estabelecidos não foram capazes de estimular as patentes verdes como modificadoras da situação econômica da região.