bluuebunny/crossref_metadata_2025 huggingface dataset:
An Overview of Virtualization and Cloud Computing
Authors: Vilasan Krishna Prasad , R Arun Kumar A. , B Radhika
Published: March 2023

Abstract: Virtualization is a technology that creates an abstract environment for underlying resources, simplifying their use and supporting replication It plays a key role in cloud computing by allowing virtual images of storage devices, servers, or network resources to be used on multiple machines. Virtualization can be implemented using a proposed model and virtual architecture. It offers greater flexibility and demand-based services while reducing the expense of accessing clients' data. Cloud computing represents a movement towards intensive resource sharing and utilization. It delivers different types of services via the internet and provides application virtualization by abstracting the application layer from the operating system Virtualization in cloud computing offers several benefits, including flexibility, data protection, security against attacks, cost-effectiveness, automatic backup across multiple devices, and reduced expenses, resiliency, high availability, increased efficiency, and environmentally friendly IT.
Analysis of Spur Gear Using Composite Material
Authors: Buran Amit A. , Chopade Prof. Mahesh P. , Gorantiwar Dr. Vinod S.
Published: March 2023

Abstract: Spur gears are the simplest and widely used in power transmission. In recent years it is required to operate machines at varying load and speed. Gear teeth normally fail when load is increased above certain limit. Therefore, it is required to explore alternate materials for gear manufacturing. Composite materials provide adequate strength with weight reduction and they have emerged as a better alternative for replacing metallic gears. Composites provide much improved mechanical properties such as better strength to weight ratio, more hardness, and hence less chances of failure. So, this work is concerned with replacing metallic gear with composite material to improve performance of machine and to have longer working life. Efforts have also been carried out for modeling using 3D modelling software called SOLIDWORKS and finite element analysis of gears using ANSYS. Composite gears have been manufactured by stir casting, which is economical method. Composite gears offer improved properties over steel alloys and these can be used as better alternative for replacing metallic gears.
CloudBook Website
Authors: Padmavat Aanchal , Aggarwal Gaurav , Dhongade Madhura , Agrawal Nandini
Published: March 2023

Abstract: CloudBook is a notes-taking platform that allows users to create and organize notes in separate files with headings, subheadings, and content. The platform automatically updates the changes made when users save and sign out. While phone notepads are commonly used to write down grocery lists, to-do lists, or notes from presentations, these notes often get lost or become disorganized. Additionally, transferring them to a computer can be challenging. To address this issue, CloudBook was created to provide an organized and accessible format for note-taking. The platform includes features such as checklists, emoticons, and the ability to save external links for further reading. Users can access their notes from any device by logging into their accounts.
Silk Fibroin Hydrogel-Assisted Controlled Release of Antifungal Drug Ketoconazole
Authors: Roy Tomal Chandro , Ansary Rezaul Haque , Biswas Protyasha , Haider Md Ali
Published: March 2023

This research focused on preparing a ketoconazole-infused silk fibroin hydrogel to enhance patient compliance, leveraging the hydrogel's biocompatibility and biodegradability. The process used a 50% (v/v) ethanol, propanol, or glycerol solution treated with 2% (w/v) silk fibroin at 37°C. The use of glycerol quickened the gelation process. The hydrogel's structure was analyzed via SEM, and UV-VIS spectrometry was used to evaluate the encapsulation efficiency and ketoconazole release profile. The surface structure varied based on the formulation and the best encapsulation efficiency was observed with ethanol (60±1.78%), followed by propanol (56±2.72%) and glycerol (47±1.42%). The release profile demonstrated an initial burst release followed by 20 hours of sustained release. Furthermore, the hydrogel-encapsulated drug demonstrated effective antifungal activity against Aspergillus Niger. As a result, silk fibroin hydrogels are a promising option for controlled topical delivery of ketoconazole.

Keywords: Silk fibroin, Controlled release, Hydrogels, Drug delivery.
Antiinflammation activity of Muntingia calabura L. leaves ethanol, ethylacetate and chloroform extracts
Authors: Widyaningrum Nova Rahma , Wahyuningsih Sri Saptuti , Priyono Cipto
Published: March 2023

Muntingia calabura L. leaves extract are reported rich in flavonoidal compounds which shows a potential activity such as antidiabetic, antipyretic, analgesic and anti-inflammatory. Several subgroups of flavonoid compounds include flavones, flavanones, flavans and biflavans. This study aimed to analyze the anti-inflammatory activity of ethanolic, ethylacetate, and chloroform extracts of M. calabura L. leaves. The extraction process was carried out by maceration, where the yield of the three solvents were 19.14%; 8.41% and 6.59% w/w, respectively. The anti-inflammatory activity was carried out by observing a decrease in edema due to 1% carrageenan induction after 4 hours. The statistical results of anti-inflammatory activity showed that the ethanol extract had a significant difference with the positive control of p value < 0.05 in which a dose of 240 mg showed a decrease in edema volume (IEV) that was closed to the positive control (acetosal = 52.12%) which was 62.51% compared to the dose 60 mg and 120 mg. Furthermore, the % IEV of ethyl acetate extract of M. calabura L. leaves at a dose of 60, 120, and 240 mg were 36.30%, 26.83%, 24.24%, respectively. These results demonstrated that an average level of anti-inflammatory activity was 22.89%, and was closed to the dose of 500 mg/kg of acetosal-induced mice. Finally, the chloroform extract with the dose of 60 mg, 120 mg, 240 mg had a significant value of p < 0.05 with a positive control (acetosal). It could be concluded that the ethanol, ethylacetate and chloroform extracts of M. calabura L. leaves may have anti-inflammatory potential with acetosal as a comparison.
Review of Recycling Plastic Waste into Briquettes
Authors: Nabil Apridio Faiz An , Putri Irsya Emilia , Ariyanti Dessy , Saputro Erwan Adi
Published: March 2023

The increasing demand for energy in transportation, industry, and domestic activities around the world is the starting point of the industrial revolution that has an impact on the emergence of environmental problems. The innovation of processing waste into alternative energy sources is an idea that has good potential in overcoming dependence on conventional energy sources. Processing plastic waste into alternative fuels in the form of plastic briquettes, including tertiary recycling. Converting plastic waste into alternative fuels can be done using several variations of methods and variations of adhesive materials. On carbonization only produces one type only. Plastic briquettes (PP) can produce a higher heating value of 9982.779±240.017 cal/gram and 3.90% ash content. From plastic briquettes (PET) 7024.56 cal/gram and 0.27% ash content but also produces a high ash content, this is because there are still impurities in it. Meanwhile, for the type of adhesive with the same composition as briquettes with starch adhesive, the heat value was 6328 kcal/kg, arpus 6366 kcal/kg. Although the calorific value is higher, the arpus adhesive usually tends to produce briquettes with black smoke, this is due to the composition of the arpus which is made from rubber tree sap.
The effectivity of hand antiseptic against Staphylococcus aureus
Authors: Nurdin Gaby Maulida , Hidayah Nurul , Hidayat Naura Nazifa R. , Nurdin Erpi
Published: March 2023

This study aimed to determine the hand antiseptic products effectivity against the growth of Staphylococcus aureus bacteria. The sample used were hand antiseptic products purchased from several minimarkets, markets, and obtained from several institutions in West Sulawesi by using purposive sampling technique. Samples were evaluated using the well diffusion method with three replications. Since the study data did not meet the ANOVA test requirements, the Kruskal-Wallis analysis test was used to analyse the data, then was continued with the Mann Whitney test. The results showed the sig. value of 0.00 < 0.05 which means, there was a significant difference between hand antiseptics in inhibiting the growth of Staphylococcus aureus bacteria. The results showed that only 2 out of 10 hand antiseptic products with codes N8 and N10 were effective in inhibiting the growth of Staphylococcus aureus bacteria. This can be seen from the formation of a clear zone around the hand antiseptic.
The Green chili to reduce formaldehyde in tofu by the spectrophotometric method using Schiff reagent
Authors: Edy Agustian Yazid  , Zahroh Roihatul , Hadiyati Agita Anung
Published: March 2023

Tofu is a processed soybean food ingredient that is widely consumed by the public. Besides having a high nutritional content, tofu is also relatively cheap and easy to obtain. Tofu has a short shelf life and is easily damaged, so producers often add the preservative formaldehyde, which has been banned for use. Formalin or formaldehyde is not included in the list of food additives because they are toxic and harmful to health. This study was aimed to determine the reduction of formalin levels in white tofu by soaking green chilies. The study was carried out experimentally with the spectrophotometric method using the Schiff reagent. Absorbance measurements were carried out at a maximum wavelength of 580 nm. Parameters observed were the addition of 0% green chili solution concentration 0%; 2.5%; 5.0%; 7.5%; 10%; and 12.5% for 10 minutes of continuous immersion; 20 minutes; and 30 minutes. Based on the results of the study, it was found that each addition of green chili solution concentration reduced the formalin level along with the soaking time. The addition of 12.5% green chili solution for 30 minutes resulted in the greatest decrease in formalin levels, namely 69.82%. Based on these results it was concluded that the addition of green chili solution could reduce formalin in tofu.
Antimicrobial activity of moringa leaf infusion on Escherichia coli isolate from Musca domestica L
Authors: Kanan Maria
Published: March 2023

The Moringa oleifera can be used as a medium for the prevention and treatment of infectious diseases such as diarrhea. Diarrhea can be caused by Escherichia coli, which house flies can transmit. Moringa oleifera leaves have antimicrobial substances such as flavonoids, triterpenoids, steroids, saponins and tannins. This aim of the study was to determine the minimum inhibitory concentration of M. oleifera infusion on the growth of E. coli. This research is a laboratory experiment with Well Diffusion Agar method and dilution technique. The materials used in the study were M. oleifera leaf infusion with concentrations of 50%, 40%, 30%, 20%, and 10%, while 0% was a negative control (Aquadest). E. coli isolates were obtained from M. domestica. The results showed that the inhibition zone formed at concentrations of 50%, 40%, 30%, 20%, 10%, and 0% was 15.55 mm, 13.80 mm, 13.10 mm, 10.10 mm, and 0 mm, respectively. The minimum inhibitory concentration of leaf infusion against E. coli isolates was 25%, and the minimum bactericidal concentration could not be determined because all concentrations tested showed bacterial growth. Instead, the lowest inhibitory concentration was 25%. In concentrations of 50%, 40%, and 30%, M. oleifera leaf infusion has potent antibacterial action; at concentrations of 20%, it has moderate antimicrobial activity; and at concentrations of 10%, it is unable to inhibit the growth of E. coli. Further research is needed to determine the value of the minimum bactericidal concentration at concentrations above 25%, and it is necessary to test it on other digestive tract pathogenic bacteria.
Antimicrobial Potential of Catfish (Clarias batrachus) and Snakehead Fish (Chana striata) Mucus on Bacterial Coliform Growth and its Application as the Organic Face Mask and Lipstick
Authors: Tarigan Wenny Pinta Litna , Tarigan Christine Ulina , Halim Cherline , Valerie Jennifer , Itanza Vionita , Oeintz Russel
Published: March 2023

Mucus from snakehead fish (Chana striata) and catfish (Clarias batrachus) has the potential to be employed in organic cosmetics and wound healing. The aim of this study is to create antimicrobials from Clarias batrachus and Chana striata mucus that may inhibit the growth of coliform bacteria. It also seeks to establish the minimum inhibitory concentration of Clarias batrachus and Chana striata mucus extracts against the growth of Escherichia coli when cocoa extract is added as an internal ingredient for making face masks and organic lipstick. The content of anthocyanin in cocoa beans used as a natural colouring agent that can replace synthetic dyes. The pooled fish mucus was extracted with succeeding centrifugation and filtration. The acidic mucus extracts were tested for antimicrobial-inhibitory effects and minimum inhibitory concentration (MIC) by agar-overlay diffusion and plate dilution method, respectively. The results showed that all fish mucus extracts exhibited antimicrobial effects against tested pathogens with catfish exhibiting the highest inhibitory effects against the bacteria sample as compared to the broad-spectrum antibiotic control. Interestingly, their mucus revealed inhibitory effects against bacteria at the lowest concentration (1:4 dilution). The present findings revealed the potential antimicrobial use of freshwater fish mucus against medically-important pathogens
Design of Specific Primer for Methallothionein Gene of Tor Fish (Tor tambra)
Authors: Atifah Yusni , Afifatul Achyar
Published: March 2023

The use of heavy metal biomarkers is needed to detect and integrate heavy metals at the molecular level. Metallothionein gene is a gene that is expressed in fish organs that have been heavily polluted. The aim of the study was to find specific primers for methallothionein of tor fish. Detection of the metallothionein gene expression in PCR instruments requires a primer in the form of a short chain DNA sequence as a specific target DNA identifier. The primer design was performed in silico using the NCBI site and multiple-aligned using Geneious Prime bioinformatic software. Primers were designed according to the conserved region of these genes. The primers specificity was checked using Primer BLAST tools in NCBI. The results showed that the forward primer 1 (5'- GAT TGC GCC AAG ACT GGA ACT –3') and reverse primer 1 (5' – ATC ACG TTG ACC TCC TCA CTG -3') qualified as good primers with an amplicon size 186 bp.
Pemanfaatan Sedimen Aquatis Sebagai Filler dalam Campuran Aspal Beton Lapis Aus
Authors: Harun F. , Deseia F. , Kadir Y.
Published: March 2023

The sedimentation of Lake Limboto causes silting so that dredging is needed to be used later in road construction. This study aims to test the waste of Lake Limboto can be used as a filler in the AC-WC mixture. For the percentage of filler content in the mixture and analyze the value of Marshall characteristics using Limboto Lake sediments. Aggregate originating from AMP PT. Cahaya Nusa Sulutarindo is located in the Isimu sub-district, Gorontalo Regency. The test was carried out at the Engineering LAB, Gorontalo State Civil University. The test method is the Marshall Test which refers to the general specifications of the 2018 Revision II Road and Bridge Highways. Marshall AC-WC mixture uses an optimum asphalt content of 6.35%: sediment variation 0.1% and 0.2% all values of Marshall characteristics meet the requirements according to the general specifications for 2018 revised road and bridge construction work. Variation of 0.1% is obtained the value density 2.304; VIM 3.66; VMAs 17.91; VFA 79.56; free 1259.44; stream 3.18; a variation of 0.2% obtained a density value of 2,314; VIM 3.21; VMA 17.52; VFA 81.68; fortress 1208.08; flow 3.00. The ideal mixture material for the AC-WC mixture using Lake Limboto sediment with an optimum asphalt content of 6.35% obtained 14.0% coarse aggregate (CA) of 157.3 gr, medium aggregate (MA) 34.0% of 382.1 gr and 52.0% fine aggregate (FA) of 584.4 g without sediment, for variations of 0.1% sediment of 0.6 g and 0.2% of 1.2 g.
Analisis Penurunan Tanah Timbunan Menggunakan Metode Elemen Hingga pada Ruas Jalan Tolango-Bulontio STA 47+600
Authors: Latief I.P. , Patuti I.M. , Achmad F.
Published: March 2023

Subsidence is a change in the composition of the soil and small spaces in the soil. The method that can be chosen to reduce the rate of decline that occurs on the road is preloading and adding geotextiles. The purpose of this study was to analyze the settlement that occurred in the embankment soil before and after the geotextile was applied. The research location is on Jalan Tolango-Bulontio STA. 47+600 Wubudu Village, East Sumalata District, North Gorontalo Regency. The primary data used is the characteristics of the embankment soil, while the secondary data is in the form of plan drawings, N-SPT values, and geotextile characteristics. Land subsidence analysis was carried out by modeling in two dimensions using the finite element method with the help of the Plaxis 2d v20 application. Structural modeling using plane strain model. The results showed that the settlement of the embankment using geotextiles that the settlement of the embankment soil at point A (shoulder) was 33 mm <65 mm, while the settlement of the embankment without geotextile was greatest at point A (shoulder) of 33 mm. mm < 65 m (allowable descent). The settlement value of the embankment without geotextiles and the use of geotextiles did not have a significant difference because the geotextiles used only functioned as filtration, not as reinforcement
Pengaruh Pengalaman Tenaga Kerja terhadap Produktivitas Tenaga Kerja Proyek Konstruksi Gedung Bertingkat di Kota Palu
Authors: Fahirah F. , Nirmala N.
Published: March 2023

One measure of the success of high-rise building construction projects is the labor. High labor productivity will support timely completion of projects and more efficient use of costs. Labor productivity will be easily achieved if human resources have previous work experience. The purpose of this study was to determine the effect of labor experience on labor productivity in high-rise building construction projects in the city of Palu. Primary data collection through the distribution of questionnaires, interviews, surveys and documentation. Secondary data is obtained through information on the contractor company. Data analysis using descriptive statistics and multiple linear regression. The results showed that partially the length of time work (X1) and the level of knowledge and skills (X2) had a positive effect on labor productivity (Y) but not significantly. Meanwhile, mastery of work and equipment (X3) partially has a positive and significant effect on labor productivity (Y). Simultaneously the variable length of time/work time (X1), level of knowledge and skills possessed (X2), variable mastery of work and equipment (X3) has a positive and significant effect on labor productivity (Y) with a coefficient of determination (R2) of 88.4%.
The causal loop diagram model of flood management system based on eco-drainage concept
Authors: Fitria Rahmawati , Rahmayanti Henita , Sumargo Bagus
Published: March 2023

Flooding has been a recurrent problem in the Indonesian capital, especially in the northern part of Jakarta, along the Jakarta shore. The floods were caused by a number of sources. According to Renald et al. (2016), there are four critical factors in designing disaster-prone cities in Indonesia, namely spatial management, disaster adaptation, disaster mitigation, and technology innovation. Therefore, the development of infrastructure in Jakarta has started to use these four elements, by applying the concept of environmentally friendly drainage, specifically the concept of eco-drainage. This study aims to understand the general picture through the cause-and-effect relationship between all flood components. This study used a qualitative approach and was conducted using a dynamic system method to describe the Causal Loop Diagram (CLD) model, which provides information between interrelated variables and forms a complex system Rifaldi et al. (2021). The model generated from the dynamic system can be used for scenario analysis by showing how the interactions between the components that make up the structure of the system and the effects of feedback loops affect. The CLD model shown shows that the use of eco-drainage will directly affect the condition of 2 (two) other variables, both of which will lead to one main variable. The proposed settlement scenarios will result in policy and technical recommendations. This CLD model shows that the interaction between variables is very dynamic and affects each other massively and holistically. Combining dynamic system processes with SMWW can potentially improve the expected results in engineering and provide an alternative scenario.
Persistent Organic Pollutant exposure as a risk factor of Gestational Diabetes Mellitus: A systematic review and meta-analysis.
Authors: Kouiti Malak , Castillo-Hermoso María Ángeles , Youlyouz-Marfak Ibtissam , Khan Khalid , Thangaratinam Shakila , Olmedo-Rqeuena Rocio , Zamora Javier , Jimenez-Moleon Jose Juan
Published: March 2023

Background: The findings of individual epidemiological studies
that suggest an association between some Persistent Organic Pollutants
(POPs) and Gestational Diabetes Mellitus (GDM) are inconclusive.
Objectives: To estimate the strength of the association between
POPs exposure and GDM in a systematic review with meta-analysis.
Search strategy: MEDLINE, Scopus, and Web of Science were
searched until 2022. Selection criteria: Cohort and
case-control studies analyzing the association between POPs and GDM in
healthy pregnant women. Data collection and analysis: Quality
was assessed using QUIPS scale and standardized mean differences (SMD)
and 95% confidence intervals (CI) was pooled using random-effect model.
Main results: Fourteen articles including 11,422 participants
were selected. The risk of bias of included studies was high in 4
(28.6%), moderate in 9 (64.3%) and low in 1 (7.14%). Only six POPs
showed a significative SMD between GDM cases and controls:
Perfluorobutanesulfonic acid (PFBS) 0.33 (95% CI 0.23, 0.43; I2=0%);
Perfluorodecanoic acid (PFDA) -0.11 (95% CI -0.20, -0.01, I2 = 0.0%);
2,2’,3,4,4’,5,5’-Heptachlorobiphenyl (PCB 180) 0.37 (95% CI 0.19, 0.56;
I2=25.3%); 2,2’,4,4’,5-Decabromodiphenyl ether (BDE 99) 0.36 (95% CI
0.14, 0.59; I2=0%); 2,2’,4,4’,6-Decabromodiphenyl ether (BDE 100) 0.42
(95% CI 0.19, 0.38; I2=0%); and, Hexachlorobenzene (HCB) 0.22 (95% CI
0.01, 0.42, I2=39.6%). For other POPs, no statistically significant
association was observed. Conclusion: The available evidence is
variable on quality and results were heterogeneous making impossible to
establish a clear association between POPs exposure and risk of GDM.
Improve the methodology of epidemiological studies assessing the
association of POPs and risk of adverse clinical outcomes are needed.
Research on the mental health status of frontline medical staff during the normalization of the COVID-19 pandemic
Authors: Sun MA，Ning , Li Laiyou , Chen Shuangqin , Fan Chaoyan , Li Hongyu , Yang Shuang , Zhong Kaiying
Published: March 2023

This study aimed to investigate the relationship between personality
characteristics and psychological health of hospitals’ frontline medical
staff and provide a basis and reference for targeted psychological
health education for frontline medical staff and for the staff of
related departments to formulate relevant policies. The self-evaluation
scale of symptoms (SCL-90) was used to investigate the mental health
status of 150 first-line medical staff in Zhejiang Province in response
to the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
pneumonia.The average scores of SCL-90 and somatization,
obsessive-compulsive, depression, anxiety, hostility, terror, and
psychotic factors were significantly higher than those of the normal
sample in the first-aid medical staff of Aihu Hubei. The degree of
influence on the mental health status of the frontline medical staff in
service in Hubei is as follows, from high to low: the degree of
suspicion that they may have been infected when new coronavirus
pneumonia-related symptoms occur, the degree of fear of being infected
and thus bring the infection to their families, and whether they have
received a medical check-up recently, as well as a high level of
education (both P<0.05).The psychological health level
of the frontline medical staff is lower than the national norm. In the
context of the increasing number of confirmed cases and the new type of
coronavirus pneumonia in the absence of any specific curative
treatments, the frontline medical staff is under great psychological
pressure. It is necessary to institute targeted mental health promotion
to relieve the psychological pressure endured by the frontline medical
staff, promote their physical and mental health, and better respond to
the pandemic in China.
Third Degree AV Nodal Block in Non-convulsive Status Epilepticus
Authors: AlHariri Housam Eddine , Abohelwa Mostafa , Philips Binu
Published: March 2023

Epilepsy is one of the most common neurologic diseases affecting people
of all ages, races, sex, social classes, and geographic locations.
Cardiac arrhythmias have been associated with patients with seizure
disorders and can be a common sudden unexpected death in epilepsy. We
present a case of a 74-year-old woman with altered level of
consciousness and agitation who was found to have non-convulsive status
epilepticus and complete AV block. She was successfully managed only
with dual antiepileptic medications. Diagnosis is best made with EEG and
ECG. In general, management is made by seizure medications, while
pacemakers are still a point of debate.
NKG2D receptor regulates CD4 + T cell differentiation via interaction with dendritic cells in patients with juvenile idiopathic arthritis
Authors: zhou juan , Wang Junyan , Tao Linlin , Liu Mingyue , Tang Xue-Mei , Zhu Xiaoping
Published: March 2023

Objectives: To explore roles of NKG2D in interactions of CD4
T cells and dendritic cells (DCs) in juvenile
idiopathic arthritis (JIA) patients Methods: Peripheral blood
from active JIA patients and healthy controls were used for flow
cytometry assessments of NKG2D CD4
T cells and expressions of MICA and MICB on DCs.
NKG2D genetically modified CD4 T cells resulted from
transfection with lentiviral vectors harboring NKG2D and NKG2D siRNA.
ELISA measured supernatant cytokines in co-cultured CD4
T cells and DCs. CD4 T cell
subgroups, MICA and MICB expression on DCs was determined by flow
cytometry and transcription factors by real-time PCR. Results:
All JIA patients had significantly higher content of CD4
NKG2D T cells compared to healthy
controls (P < 0.01). Expression of NKG2D on CD4
T cells, and MICA and MICB on DCs were significantly
greater in articular JIA than systemic JIA (P < 0.05). NKG2D
induced IL-12 and suppressed IL-10 and TGF-β from CD4
T cells, increased IFN-γ CD4+ T
and IL-17 CD4 T cells, RORc and
T-bet, but reduced CD25 Foxp3
CD4 T cells, IL-4 CD4
T cells, Foxp3, and GATA3 in JIA patients
(P<0.05). NKG2D increased IL-12 and T-bet by CD4
T cells in healthy controls (P<0.05).
NKG2D decreased IL-10 and increased CD83, MICA, and MICB of DCs via
interaction with CD4 T cells in JIA and control
patients (P<0.05). Conclusions: NKG2D regulates
differentiation of CD4 T cells directly and the
maturation of DCs indirectly. Targeting NKG2D may be a potential therapy
for JIA.
Online Correlation Analysis and FCM-based Fault Detection of Current and Speed Signals for Underwater Thruster Entanglement
Authors: Yuan Jian , Zhang Wenxia , Liu Hailin
Published: March 2023

The fault diagnosis with one single sensor cannot comprehensively use
the multi-sensor correlation information of fault signals for underwater
thruster entanglement. To solve the real-time fault diagnosis problem
that in the case of entanglement, a kind of fault diagnosis method based
on the combination of current and rotational speed signal correlation
analysis and Fuzzy C-means clustering (FCM) is proposed. Firstly, the
collected current and speed signals of underwater thrusters under
different states are normalized; Secondly, the correlation of normalized
current and speed signals is calculated, and the correlation matrix is
formed, and the sliding window of sampling series is adopted to
calculate the correlation coefficient change over time between current
and speed. Then a kind of Fuzzy C-means clustering method based on
improved distance index is used to diagnose fault with correlation
matrix elements. To verify the effectiveness of the proposed method, the
sampling data in the case of propeller entanglement is used to verify
the proposed fault detection method. The results show that the proposed
method can fully extract the multi-sensor correlation information of
underwater thrusters compared with the fault diagnosis method using only
one signal using Support Vector Machine, and the feature extraction is
more sufficient, effectively improving the accuracy of underwater
thruster fault diagnosis.
Long-term Outdoor Study of Organic Photovoltaics for Building Integration
Authors: Pravettoni Mauro , Luo Wei , KHAING Aung Myint , Gallegos Carlos Rodríguez , Reindl Thomas
Published: March 2023

Organic photovoltaics (OPV) has attracted tremendous attention as a
promising alternative to silicon wafer-based technologies for building
integration. While significant progress has been achieved on the power
conversion efficiency of OPV technologies, their field stability is
rarely studied. This work investigates the field performance and
reliability of a large-area OPV module designed for BIPV application in
the tropical region of Singapore for 4.5 years. The device suffered more
than 14% degradation in power at the standard testing conditions from
the initial performance, largely due to losses in fill factor (-12%
relative). During the monitoring period, it exhibited comparable
performance to more conventional silicon PV technologies, with an
average specific energy yield of about 4 kWh/kWp/day and an average
performance ratio of 0.96. Excellent performance at low light conditions
was also observed. However, its field performance was heavily impacted
by soiling, which typically led to a 5 to 10% loss in the current
output after several months. Further, the device’s outdoor performance
also showed a three-stage degradation process, including (1) an initial
slow degradation in the first two years (about -1%/year), (2) a stable
period with negligible performance loss from year 2 to year 3.5 and (3)
a rapid degradation in the last year (about -5%/year).
Genomic assessment of a declining game bird reveals cryptic genetic structure and insights for population management
Authors: Luna Leilton , Williams LIsa , Duren Kenneth , Tyl Reina , Toews David , Avery Julian
Published: March 2023

Population genomics applied to game species conservation can help
delineate management units, ensure appropriate harvest levels, and
identify populations needing genetic rescue to safeguard their adaptive
potential. The ruffed grouse (Bonasa umbellus) is rapidly declining in
much of the eastern USA due to a combination of forest maturation and
habitat fragmentation. More recently, mortality from West Nile Virus may
have affected connectivity of local populations; however, genetic
approaches have never explicitly investigated this issue. In this study,
we sequenced 54 individual low-coverage (~5X) grouse
genomes to characterize population structure and assess migration rates
across the landscape to identify potential barriers to gene flow.
Surprisingly, we identified two genomic clusters with no clear
geographic correlation, with large blocks of genomic differentiation
associated with chromosomes 4 and 20, likely due to chromosomal
inversions. After excluding these putative inversions from the data set,
we found weak but non-significant signals of population subdivision.
Estimated gene flow revealed reduced rates of migration in areas with
extensive habitat fragmentation, while areas with more habitat
continuity showed higher rates of genetic connectivity. Our findings
provide a benchmark for wildlife managers to compare and scale the
genetic diversity and structure of ruffed grouse populations in
Pennsylvania and across the eastern USA, as well as reveal unexpected
structural variation in the grouse genome that requires further study to
understand its possible effects on individual fitness and population
distribution.
CAN DIVIDEND PAYMENTS MITIGATE THE INFLUENCE OF COVID-19 CRISIS ON EARNINGS MANAGEMENT?
Authors: Azevedo Yuri Gomes Paiva , Tortoli Júlia Peres , Stanzani Livia Maria Lopes , Gaio Luiz Eduardo
Published: March 2023

This paper examines whether dividend payments mitigate the influence of COVID-19 crisis on earnings management practices in Brazil. For this purpose, we use a sample of 264 Brazilian public firms from 2010 to 2021, applying System Generalized Method of Moments (SYS-GMM) regressions. Our main results indicate that, although firms are more prone to engage in earnings management practices during the COVID-19 period, the dividend payout ratio mitigates this influence on earnings management level. Therefore, we show that dividend payment can act as a substitute corporate governance mechanism in times of crisis, since it can reduce the occurrence of earnings management. Additional analyses also support this view, showing that big levels of dividends play a role in minimizing agency conflicts by reducing the level of earnings management. Hence, we contribute to the literature on dividend policy and earnings management, which calls for research to better understand the influence of dividends on earnings management practices in financial crises periods. Further, we shed light on how firms can use dividend policies as a substitute corporate governance mechanism to maintain or establish its reputation during periods of financial crises, benefiting investors, boards, creditors, financial analysts, and policymakers due the increase on the financial reporting quality.
TOXICIDADE DOS FLUXOS DE ORDENS SOBRE A LIQUIDEZ DOS CONTRATOS FUTUROS DE DI E DÓLAR COMERCIAL
Authors: Ribeiro João Eduardo , Correia Laise Ferraz , Paiva Felipe Dias
Published: March 2023

O objetivo deste estudo foi analisar o impacto da toxicidade dos fluxos de ordens – Volume-Synchronized Probability of informed trading (VPIN) – dos contratos futuros de DI e de Dólar Comercial negociados na Brasil Bolsa Balcão (B3) sobre a liquidez de mercado desses ativos – representada pelo bid-ask spread. Argumenta-se que a assimetria de informações entre os agentes participantes de uma transação gera um desequilíbrio entre as ordens lançadas, o que afeta a liquidez dos títulos. Empiricamente, utilizaram-se dados intradiários de contratos futuros de DI e Dólar Comercial negociados na B3 de setembro de 2018 a agosto de 2019 para estimar um modelo de regressão linear múltipla e analisar esse relacionamento. Os resultados encontrados mostraram que a relação entre a VPIN e o bid-ask spread foi significante e positiva nos modelos estimados para ambos os contratos. Dessa forma, concluiu-se que a VPIN é um dos fatores que impactam a liquidez nas negociações de DI Futuro e Dólar Comercial Futuro, ou seja, quanto maior a toxicidade do fluxo de ordens (maior grau de assimetria informacional), menor a liquidez dos títulos negociados.
NATUREZA DA CIÊNCIA NA EDUCAÇÃO BÁSICA: UMA ANÁLISE DE DOCUMENTOS CURRICULARES OFICIAIS
Authors: Silva de Souza Caroline Batista , Santos Santana Uilian dos , Meneses Moura Antonio Reynaldo , Sedano de Souza Luciana
Published: March 2023

Ser cientificamente alfabetizado demanda conhecer aspectos da Natureza da Ciência, determinados conceitos e conteúdos científicos, saber reconhecer seu contexto e aplicá-los às situações do cotidiano. Por isso, compreender de que forma os documentos que orientam a educação discutem a Natureza da Ciência é fundamental. Diante disso, o objetivo deste estudo é identificar e analisar a abordagem de aspectos da Natureza da Ciência em documentos curriculares oficiais voltados à Educação Básica. Para isso, analisamos as Diretrizes Curriculares Nacionais para a Educação Básica – DCNEB, a Base Nacional Comum Curricular – BNCC e a National Research Council, A Framework for K-12 Science Education. A análise denotou que Framework for K-12 Science Education discute enfaticamente a Natureza da Ciência, enquanto que as DCNEB e a BNCC realizam aproximações ainda incipientes dos aspectos de Natureza da Ciência.
FORMAÇÃO DE PROFESSORES: ESTADO DO CONHECIMENTO DAS PRODUÇÕES ACADÊMICAS DO PPGE - UFT (2014-2021)
Authors: Anjos de Carvalho Kely Rejane Souza dos , Reis de Sousa Graciene , Leoncio Macedo Maria de Lourdes , Santana dos Santos Jocyleia
Published: March 2023

A presente investigação visa a apresentar o estado do conhecimento sobre a formação docente nas produções acadêmicas do Programa de Pós-Graduação em Educação (PPGE), stricto sensu, da Universidade Federal do Tocantins (UFT), entre os anos de 2014 e 2021. A metodologia utilizada foi do tipo estado do conhecimento com caráter bibliográfico. A base de dados utilizada para a execução do mapeamento foi o Repositório Institucional da UFT (RIUFT), tendo como corpus da investigação 56 resumos, com apenas seis trabalhos que abordam diretamente a temática estudada. Têm-se como objetivos: compreender as temáticas estudadas; identificar metodologias aplicadas; conhecer o público-alvo das investigações e descrever os resultados encontrados nas pesquisas. Os resultados demonstram que não há um consenso entre os pesquisadores sobre o formato dos resumos depositados no RIUFT e que não há um interesse consolidado, por parte dos pesquisadores, acerca da formação de professores, visto um inexpressivo número de trabalhos encontrados. A pesquisa constata, também, que, no âmbito do PPGE, não há trabalhos com enfoques inovadores relacionados à temática: “formação de professores”, assim como a necessidade de incluir no RIUFT as produções acadêmicas oriundas do PPPGE da UFT.
EXPERIÊNCIA EDUCATIVA PARA SUPERAR ASPECTOS NEGATIVOS DA PANDEMIA DA COVID-19 NA ESCOLA PÚBLICA
Authors: Nascimento Sabino Raquel do , Luna Freire Chaves Patrícia Menezes de , Sabino Neves Vanusa Nascimento , Fiuza Fialho Lia Machado
Published: March 2023

Objetivou-se compreender a experiência educativa desenvolvida em uma escola pública municipal durante a suspensão das aulas presenciais devido à pandemia de Covid-19, que possibilitou dar prosseguimento ao processo de ensino e aprendizagem para alunos em situação de vulnerabilidade. Uma pesquisa-ação, de abordagem qualitativa, foi desenvolvida no ano de 2020 por uma equipe multidisciplinar pedagógica em uma escola pública da educação básica de João Pessoa, capital da Paraíba, que cumpriu as fases: exploratória, levantamento de estratégias resolutivas, ação e avaliação. Concluiu-se que os múltiplos percalços para prosseguir com o ano letivo interrompido e para implementar o ensino remoto emergencial para alunos em contexto de vulnerabilidade social foram minorados pelas ações colaborativas da equipe pedagógica, com inclusão de alunos, familiares e Poderes Legislativos e Executivo Municipal. Ainda assim, a evasão escolar foi elevada, requisitando políticas públicas abrangentes da problemática que considerem as causas, além dos limites espaciais da escola.
PROFESSORES PEDAGOGOS E SUA RELAÇÃO COM O SABER MATEMÁTICO
Authors: Gentilin Cavalaro Adriana , Meneghello Passos Marinez , Mello Arruda Sergio de , Souza Santana Miderson Andrei de
Published: March 2023

Neste artigo trazemos os resultados de uma pesquisa que entrevistou professores pedagogos do Ensino Fundamental Anos Iniciais a respeito da sua relação com o saber matemático, enquanto docentes que ensinavam Matemática na Educação Básica. Para analisar o que os pedagogos manifestaram durante as entrevistas, consideramos a Matriz 3x3 ou Matriz do Professor, que foi um instrumento idealizado com o intuito de compreender como o professor se relacionava com o conteúdo que ministrava, com o ensino que praticava e com a aprendizagem do aluno, sempre assumindo esses três significantes (Conteúdo, Ensino e Aprendizagem) em três dimensões: Epistêmica, Pessoal e Social. Tendo as 9 células da Matriz do Professor como categorias a priori, ao fim do processo analítico, evidenciou-se que em 3 delas foi alocada a maioria das manifestações: 1B, que “Diz respeito ao conteúdo enquanto objeto pessoal”; 2B, que “Diz respeito ao ensino enquanto atividade pessoal”; 2A, que “Diz respeito às relações epistêmicas que o professor estabelece com o ensino que pratica”.
The role of intestinal translocation of E.coli in the development of acute obstructive pyelonephritis in an experiment
Authors: Sharapatov Yerzhan , Turgunov Yermek , Lavrinenko Alyona
Published: March 2023

Aim: To study the role of E. coli intestinal translocation in the development of acute obstructive pyelonephritis in an experiment.

Material and methods: An experimental study was conducted on 60 male rabbits weighing 3000±500 g. The animals were divided into 3 groups of 20 animals each: experimental, control and intermediate control group. The acute obstructive pyelonephritis with the ureter blocking by laparotomy and introduction of the strain into the intestine were simulated in the animals of the experimental group. In the control group, the model was performed anologically as in the experimental group, but without the ureter blocking. In the intermediate control group, laparotomy was performed, the ureter was isolated without blocking and without the introduction of a bacterial strain. 10 animals of each group were removed from the experiment on the 3rd and 5th days, kidney tissue and urine were intake. As a reference marker strain, the laboratory strain E. coli No. 49579 was used, which was obtained from a patient with a urological infection and had resistance to cefepime, ciprofloxacin and tetracycline. Biomaterials were studied by microbiological examination and subspecific typing of strains using the MALDI-TOF MS method, antibiotic sensitivity was determined.

Results: E. coli strain was isolated in all animals of the experimental group and in 2 animals of the control group on the 5th day. During subspecific typing by the MALDI-TOF MS method, the isolated strains were identical in ribosomal proteins, and also had the same sensitivity to the said antibiotics. When analyzing the amount of lg CFU E.coli in urine after the experiment between the experimental and control group, we found that, on day 3, there were statistically significant differences between the groups (p=0.005), and on day 5, the amount of lg CFU E.coli was 13 times greater (p=0.004).A comparative analysis of the lg CFU E.coli index in kidney tissue on 3 (p=0.004) and 5 (p=0.003) days revealed statistically significant differences between the experimental group and the control group.

Conclusion: The results of identification and subspecific typing of isolated microorganisms confirmed that the strains isolated from the urinary tract were identical to the reference strain introduced into the gastrointestinal tract during the experiment, which confirms the role of translocation of intestinal microorganisms in the development of acute obstructive pyelonephritis.
The Influences of Competency and Compensation on Employee Performance at PT Balai Pustaka (Persero) as Mediated by Work Engagement
Authors: Salsabila Nada , Lo Singmin Johanes
Published: March 2023

This study aims to analyze the influences of competency and compensation on employee performance as mediated by work engagement. The population of this study is permanent employees at PT Balai Pustaka (Persero) with a total sample of 69 (sixty-nine) employees. The data analysis method uses Structural Equation Model-Partial Least Square (SEM-PLS) using SmartPLS 3.2.8. The results found that competency has positive and significant impact on employee performance and work engagement; compensation has positive but insignificant impact on employee performance, on the other hand compensation has positive and significant impact on work engagement; work engagement has negative and insignificant impact on employee engagement. Meanwhile, work engagement does not mediate both competency and compensation on employee performance. The company leadership is suggested to increase employee’s competency to increase employee performance.
Geo-Cultural Identity and Multiculturalism in Kiran Desai’s The Inheritance of Loss
Authors: Tripathi Sharma Dr. Shreeja
Published: March 2023

Harmonizing the concerns of geo-cultural claims posited against the ‘melting-pot’ ideology of multicultural societies is a challenge for negotiating a cultural identity. Dominant strains of geo-cultural identities often involve problematising structures such as language, ethnic identity, territorial autonomy, environmental concerns and immigrant rights. This paper seeks to explore Desai’s The Inheritance of Loss for representing the polarities through the sketches of diverse cultural entities whom she conjoins in the mesmeric ‘culture-space’ of the novel. The characters, Jemubhai, Sai, Gyan and Biju, traverse the liminal thresholds of cultural identity within and between the geo-cultural and multicultural space.
Selanik İngiliz Konsolosluğu Ticaret Raporlarına Göre Selanik Limanında İngiliz Ticareti (1865-1912)
Authors: AKSOY Nimet Ayşe
Published: March 2023

Selanik limanı, coğrafî konumu itibariyle Orta Doğu, Karadeniz, Kuzey Afrika ve Balkanları birbirine bağlayan ticaret yollarının üzerinde bir ara istasyondur. İngilizler, XVII. yüzyıldan beri aktif bir ticarete sahip olan Selanik’e XVIII. yüzyılın başından itibaren ticarî amaçla daha sık gelmeye başlamışlardır. 1718’de Selanik’te İngiliz konsolosluğunun açılmasıyla Fransız konsoloslarının himayesinden kurtulan İngiliz tüccarlar daha iyi şartlarda ticarî faaliyetlerini sürdürmüşlerdir. Selanik limanına ilk buharlı geminin yanaşması yine İngilizler vasıtasıyla gerçekleşmiştir. Özellikle 1860’lı yıllardan itibaren Selanik ticaretinde İngiliz payı hem gemicilik hem ithalat hem de ihracat boyutuyla artış kaydetmiştir. Selanik hinterlandının tahıl ve endüstriyel tarım ürünlerinin alıcısı olan Britanya, Selanik limanına pamuklu iplik ve tekstil başta olmak üzere karyoladan çuvala kadar çok çeşitte ürünler ithal etmiştir. İthalat ve ihracatın yanısıra Selanik limanında İngilizler oldukça aktif bir taşımacılık da yapmıştır. Bu çalışmada, Britanya’nın Selanik’te görevli konsoloslarının hazırlamış oldukları ticaret raporlarına göre Selanik limanındaki İngiliz gemiciliğinin ve ticaretinin boyutları ele alınmaktadır.