bluuebunny/crossref_metadata_2025 huggingface dataset:
Elementa Curvarum Linearum more Apollonius that Descartes
Authors: Bello-Chávez Jhon Helver
Published: October 2021

This document shows an analysis of the second book Elementa Curvarum Linearum written by Jan De Witt, published for the first time in the second edition of Geometry [1]. This writing is considered the first analytical geometry textbook. The influence of the work carried out by Apollonius in his conics book is studied, the use and interpretation of diagrams is debated. The development of the analytical method and the generation of curves by means of movement are also studied. Some propositions were renewed versions in terms of eighteenth-century mathematics, they used symbology, algebraic techniques and curves were classified by means of their symbolic representations, in these propositions a work closer to Apollonius is seen, the conic is not generated, it is assumed its existence, its nature is geometric. The study concludes that, although the textbook was published in the second edition of Geometry, the genesis of the curves remains geometric. The conics appear as objects of study in action immersed in the symbolic and algebraic practice characteristic of the time.
Accelerating large scale real-time GNN inference using channel pruning
Authors: Zhou Hongkuan , Srivastava Ajitesh , Zeng Hanqing , Kannan Rajgopal , Prasanna Viktor
Published: October 2021

Graph Neural Networks (GNNs) are proven to be powerful models to generate node embedding for downstream applications. However, due to the high computation complexity of GNN inference, it is hard to deploy GNNs for large-scale or real-time applications. In this paper, we propose to accelerate GNN inference by pruning the dimensions in each layer with negligible accuracy loss. Our pruning framework uses a novel LASSO regression formulation for GNNs to identify feature dimensions (channels) that have high influence on the output activation. We identify two inference scenarios and design pruning schemes based on their computation and memory usage for each. To further reduce the inference complexity, we effectively store and reuse hidden features of visited nodes, which significantly reduces the number of supporting nodes needed to compute the target embedding. We evaluate the proposed method with the node classification problem on five popular datasets and a real-time spam detection application. We demonstrate that the pruned GNN models greatly reduce computation and memory usage with little accuracy loss. For full inference, the proposed method achieves an average of 3.27X speedup with only 0.002 drop in F1-Micro on GPU. For batched inference, the proposed method achieves an average of 6.67X speedup with only 0.003 drop in F1-Micro on CPU. To the best of our knowledge, we are the first to accelerate large scale real-time GNN inference through channel pruning.
Extended homogeneous balance conditions in the sub-equation method
Authors: Song Chenwei , Liu Yinping
Published: October 2021

The sub-equation method is a kind of straightforward algebraic method to construct exact solutions of nonlinear evolution equations. In this paper, the sub-equation method is improved by proposing some extended homogeneous balance conditions. By applying them to several examples, it can be seen that new solutions could indeed be obtained.
Primary intradural extramedullary extraosseous Ewing’s sarcoma/peripheral primitive neuroectodermal tumor (PIEES/PNET) of the thoracolumbar spine: A case report and literature review
Authors: Pu Feifei , Liu Jianxiang , Zhang Zhicai , Guo Tao , Shao Zengwu
Published: October 2021

We present a rare case of a primary intradural extramedullary Ewing’s sarcoma/peripheral primitive neuroectodermal tumor (PIEES/PNET) in the thoracolumbar spine and review the current literature. We describe the imaging manifestations, pathological features, surgical methods, and patient survival to shed light on the clinical management of this rare tumor. A 32-year-old man experienced progressive low back pain for more than 1 month. An intradural extramedullary tumor from T12 to L2 was detected on magnetic resonance imaging. He underwent a thoracolumbar laminotomy for decompression, complete excision of the intradural extramedullary tumor, and internal fixation with pedicle screws. A histopathological examination confirmed that the tumor was a PIEES/PNET via an immunohistochemical study of the surgically resected tissues. Postoperatively, the patient received chemotherapy and radiotherapy. No recurrence, metastasis, or failure of internal fixation were noted at a 17-month post-surgery radiographic examination. PIEES/PNET of the thoracolumbar spine is extremely rare. Treatment is difficult because the current literature is sparse and cases are rare. Complete resection combined with chemotherapy and radiotherapy effectively reduces recurrence and metastasis.
Hotspots for textual dynamics: cultural semiotic approach to digital archives
Authors: Ojamaa Maarja , Ibrus Indrek
Published: October 2021

Digital cultural archives and databases are promising an era of heritage democratization and an enhancement of the role of arts in everyday cultures. It is hoped that mass digitization initiatives in many corners of the world can facilitate the secure preservation of human cultural heritage, with easy access and diverse ways for creative reuse. Understanding the dialogic processes within these increasingly vast databases necessitates a dynamic conceptualization of data they contain. The paper argues that this can be found in Juri Lotman’s cultural semiotic notion of text and text’s functions in culture. It elaborates on the three key characteristics of text – expression, boundary, and structure – as manifested within the digital semiosphere. At the same time, the textual dialogues within digital archives are increasingly conditioned by metadata, which is hereby conceptualized as metalanguage inducing a modeling effect on archived texts and defining their possible sphere of dynamics. To balance the explanations of creative operations of digital archives, the paper also demonstrates their auto-communicative mechanisms for facilitating cultural continuities and stability.
“The toxic offspring of the viper’s seed”: Augustine’s 418 Encounter with Emeritus of Caesarea Mauretaniae
Authors: Dunn Geoffrey D.
Published: October 2021

In 418 Augustine encountered Emeritus, one of his Donatist adversaries, in Caesarea Mauretaniae (modern Cherchell) in Mauretania Caesariensis. In the resultant work, Gesta cum Emerito, Augustine relived some of the arguments that had earlier been employed against the Donatist in 411, particularly by having Alypius read out passages of Aurelius’ 411 letter to Marcellinus, the imperial commissioner (Epistula 128). Not only does Augustine shape our understanding of the 418 encounter but continues to take control of how the 411 confrontation was to be remembered. This paper will examine how Gesta cum Emerito saw the Donatist weakness in 411 being based upon their inconsistencies in dealing with schismatics, especially their treatment of Maximianists at the 394 synod in Bagaï, where Emeritus himself had condemned Maximian as “the toxic offspring of the viper’s seed.” The encounter gave Augustine an opportunity to highlight the Maximianists to an extent greater than the records of 411 indicate had been the case then.
Wirtschaftliche Mensch-Roboter-Arbeitssystemgestaltung
Authors: Komenda Titanilla , Spitzhirn Michael , Spinner Caroline , Schlund Sebastian
Published: October 2021

Im Rahmen der Planung von Arbeitssystemen mit Mensch-Roboter-Zusammenarbeit können digitale Planungswerkzeuge mit ihren Funktionen zur Visualisierung und parametrischen Simulation in Kombination mit ergonomischen Bewertungen der Arbeitsprozesse einen wesentlichen Mehrwert zur wirtschaftlichen Arbeitssystemgestaltung darstellen. Im Beitrag wird anhand einer digitalen Arbeitsplanung am Beispiel eines Platinenverpackprozesses gezeigt, wie sich Gestaltungsvarianten eines Mensch-Roboter-Arbeitssystems auf Produktivität, Wirtschaftlichkeit, Sicherheit und Ergonomie auswirken.
Automatisierte Erstellung von Virtual-Reality-Schulungen
Authors: Masuhr Christian , Geiger Andreas , Konkol Kathrin
Published: October 2021

Für den effizienten Einsatz von Automatisierungstechnik ist qualifiziertes Instandhaltungspersonal notwendig, um operative Störungen schnell zu beheben. Diese Schulungen finden heutzutage entweder an realen Anlagen, oder auch bereits in eigens für bestimmte Anwendungsfälle entwickelte VR-Anwendungen statt. Zur Minimierung des Aufwands zur Erzeug von VR-Trainingssimulationen können jedoch bereits existierende Modelle und Simulationen aus dem Prozess der virtuellen Inbetriebnahme genutzt. Die Grundlage für das Training sind eine digitale Simulation und Vernetzung von realer Anlagensteuerung, Robotersteuerung und HMI-Schnittstellen. Dadurch können die Kosten reduziert und die Anzahl von unterschiedlichen Trainingsumgebungen skaliert werden. Die Trainingssimulation wird durch weitere motivierende Elemente erweitert.
Current problems in the low-frequency dynamics of liquid-propellant rocket propulsion systems
Authors:   Institute of Technical Mechanics of the National Academy of Sciences of Ukraine and the State Space Agency of Ukraine, Pylypenko O.V. , Nikolayev O.N. ,   Institute of Technical Mechanics of the National Academy of Sciences of Ukraine and the State Space Agency of Ukraine, Khoriak N.V. ,   Institute of Technical Mechanics of the National Academy of Sciences of Ukraine and the State Space Agency of Ukraine, Dolgopolov S.I. ,   Institute of Technical Mechanics of the National Academy of Sciences of Ukraine and the State Space Agency of Ukraine, Bashliy I.D. ,   Institute of Technical Mechanics of the National Academy of Sciences of Ukraine and the State Space Agency of Ukraine
Published: October 2021

One of the key problems in liquid-propellant rocket engine (LPRE) design is to provide the stability of LPRE working processes, in particular low-frequency stability. In LPRE experimental tryout, every so often there occur situations where the development of divergent oscillations set up in some of the LPRE loops or units results in contingencies: exceeding the engine ultimate strength, pump stall, chamber ignition, etc. Such contingencies may lead to grave consequences, including engine and bench equipment failure. Because of this, mathematical simulation is one of the main tools that allow one to predict he dynamic performance of an LPRE both in its steady operation and in transients and its startup operation features at the design and tryout stage. This paper overviews and analyzes scientific publications for the past 15 years concerned with the study of the dynamics and low-frequency stability of advanced LPREs and units thereof along different lines. This analysis made it possible to identify problems in low-frequency stability prediction and assurance for liquid-propellant rocket propulsion systems (LPRPSs) under design, to cover new research results (experimental and theoretical) on the origination and development of all-engine low-frequency oscillations and low-frequency oscillations in LPRPS systems and units and to identify new approaches to the mathematical simulation and study of low-frequency processes in LPRPSs and promising lines of investigation. The man lineы of the analysis are as follows: the low-frequency dynamics of cavitating inducer-equipped centrifugal pumps and LPRE gas paths, LPRE thrust control problems, the interaction of launch vehicle airframe longitudinal oscillations with low-frequency processes in the sustainer LPRPS, dynamic processes during an LPRE startup/shutdown, and low-frequency in-chamber oscillations.
Structured-light three-dimensional scanning for process monitoring and quality control in precast concrete production
Authors: Wang Rongxuan , Wang Yinan , Devadiga Sonam , Perkins Isaac , Kong Zhenyu (James) , Yue Xiaowei
Published: October 2021

Quality control is a crucial step in the fabrication of precast concrete products. There are three critical quality features: the fabrication consistency of surface finish, the dimensional accuracy of the overall geometry, and the positioning accuracy of the embedded parts. Existing quality control methods rely on tape measures and inspectors’ experience, which may lead to measurement inconsistency, operator faults, and safety hazards. This paper proposes an innovative real-time quality inspection system for the three critical quality features. The system first uses a structured-light three-dimensional scanner to capture the surface and geometric data from the precast concrete parts and then calculates and visualizes the deviations by applying specially developed algorithms. In addition, all of the functions are compiled into a graphical user interface that can be easily used by operators without a data analytics background. The system has been tested on a precast concrete sample with five different surface finishes in five regions of the sample, complex geometries, and a variety of embedded parts. The experiment results show that the proposed quality inspection and data analysis system can obtain critical quality information efficiently and accurately.
New or Little-Known Epiphyllous Liverworts, XXIV. A Collection Made in the Venezuelan Guayana at the Foot of Salto Angel with Description of Cololejeunea Bencei
Authors: Pócs T.
Published: October 2021

A liverwort collection by Bence Pócs from the Venezuelan Guayana resulted in 31 species of liverworts, including Cololejeunea bencei new to science and C. cardiocarpa, C. obliqua, C. platyneura, C. schusteri, C. verwimpii, Lejeunea pulchra and Plagiochila crispabilis new to Venezuela. The distribution and differentiation of C. schusteri is discussed.
AS REVIRAVOLTAS DO DIVERTIMENTO EM PASCAL
Authors: Oliva Luís César Guimarães
Published: October 2021

RESUMO Longe de criticar o divertimento como mera futilidade, Pascal o considera um dispositivo de sobrevivência incontornável para a condição humana, continuamente ameaçada pelo tédio (ennui). O que ainda não é totalmente claro, porém, é o alcance desta incontornabilidade. Em outras palavras: o cristão também se diverte ou o divertimento é um caminho necessário apenas ao não cristão? Trata-se de uma descrição fenomenológica dos comportamentos humanos, sem implicação para o projeto apologético pascaliano, ou de um elemento constitutivo deste último? Essas perguntas fazem necessário um retorno ao tema, analisando os principais fragmentos que o exploram e retomando alguns intérpretes fundamentais. Ao final, pretendemos ter mostrado que o divertimento só pode ser contornado quando ocorre a intervenção sobre-humana da graça.
Absenteísmo docente em escolas públicas paulistas: dimensão e fatores associados
Authors: Tavares Priscilla , Honda Lucas
Published: October 2021

Resumo Esse é o primeiro artigo da literatura brasileira que analisa fatores associados ao absenteísmo docente. Utilizamos informações administrativas da rede estadual paulista, Censo Escolar e SARESP 2007 e estimamos um modelo de contagem que relaciona as faltas dos professores aos seus atributos, às características das escolas e dos alunos. Nesse ano letivo, 71% dos profissionais ausentaram-se pelo menos uma vez ao trabalho e 26 dias letivos foram perdidos na instituição mediana. Os resultados mostram que as faltas estão associadas a problemas de saúde, ao custo de oportunidade e as chances de ser punido. Unidades escolares com alunato mais pobre e más condições de trabalho sofrem mais com as ausências. Há evidências de que o ambiente institucional afete a decisão de faltar. Efeitos heterogêneos mostram que políticas para reduzir o absenteísmo devem levar em conta o perfil da escola e do professor.
Efeito-China no valor adicionado e no comércio em Cadeias Globais de Valor
Authors: Black Clarissa
Published: October 2021

Resumo No contexto das Cadeias Globais de Valor (CGV), este artigo tem o objetivo de demonstrar os impactos da economia chinesa no comércio internacional e na distribuição do valor adicionado (VA) mundial, no século XXI. Para isso, primeiramente, foi discutida a evolução da literatura sobre as formas de mensurar o valor do comércio que melhor reflete a dinâmica contemporânea das CGV. Em segundo lugar, foi aplicada a decomposição de Borin e Mancini (2017) nos dados da World Input_Output Database (WIOD) no período 2000-2014. O artigo contribui para a literatura ao apresentar a evolução da metodologia sobre o tema, assim como, ao demonstrar as mudanças estruturais que o crescimento chinês provocou na fragmentação produtiva em CGV e na distribuição do VA mundial em termos setoriais. Destaca-se, ainda, que os dados convergem para a literatura prévia, que sugere um reequilíbrio do crescimento chinês e um processo substituição de importações do país.
Sobre poéticas e políticas do circum-roraima: o caso do Watunna ye’kwana
Authors: Fonseca Isabel Maria , Leal Izabela
Published: October 2021

Resumo Este ensaio discute aspectos relativos à produção das textualidades indígenas, tomando como referência duas versões do Watunna, a cosmogonia ye’kwana: a do francês Marc de Civrieux e a do ye’kwana Marcos Rodrigues. Para tanto, acerca-se da pluralidade poética indígena do circum-Roraima, que é um rico espaço em termos de diversidade humana e cultural, localizado na tríplice fronteira Brasil-Guiana-Venezuela. Nossa proposta parte do pressuposto da necessidade de se cultivar uma área de investigação que aproxime a teoria literária da antropologia e que atente para as particularidades advindas das culturas e línguas indígenas. Isso significa que o registro escrito das artes verbais indígenas põe em jogo um processo complexo de criação, recriação, tradução e circulação, envolvendo não apenas uma dimensão poética, como também uma dimensão ética e política.
Perder el norte: Nancy Huston y el imaginario de las lenguas
Authors: Roux Maya González
Published: October 2021

Resumen Nancy Huston “entró” en la literatura mediante un cambio de lengua: escribir en francés, y abandonar por un momento su inglés nativo, marcó el comienzo de su escritura y más tarde la condujo a interrogarse sobre su propia identidad. ¿Por qué dejar atrás su “lengua materna”? ¿Se puede abandonar para siempre una lengua, el lugar de origen y reinventarse en otro lugar? El presente trabajo se propone avanzar con estas preguntas a partir de su libro Nord perdu en el que la autora se detiene en los recuerdos de la infancia en Canadá y en Alemania, y en su percepción de extranjera en Francia. Tal vez la respuesta a aquellas preguntas se encuentre en la blancura de la nieve, paisaje de su infancia en el que murmuran las lenguas de Huston.
A SUJEIÇÃO COMO PROCESSO PARADOXAL DE PODER: DA CONSTITUIÇÃO PSÍQUICA À ÉTICA DO DESEJO
Authors: ANDRADE CLEYTON SIDNEY DE , MARIZ INÁCIO ANTONIO SILVA DE
Published: October 2021

RESUMO: Descreveremos o processo paradoxal de poder que constitui a sujeição psíquica segundo Judith Butler e sua relação com a constituição do psiquismo em psicanálise. A interlocução entre Butler e a psicanálise deve-se ao fato de que a autora se utiliza de um aporte teórico psicanalítico no desenvolvimento das ideias. Veremos como o poder opera na internalização da consciência de culpa, e como são ambivalentes e dinâmicos os efeitos do poder na neurose e nos processos de sujeição social. Finalmente, veremos que esse poder opera na ordem fundamental das coisas, de onde se origina o desejo manifesto na realidade a partir de uma ação ética.
IMAGENS: A POLÍTICA DO APARECIMENTO E DO DESAPARECIMENTO
Authors: Paz Luciene de Melo , Melo Maria de Fátima Vilar de , Donard Véronique
Published: October 2021

RESUMO: Um dos efeitos das transformações contemporâneas é a ausência de referência para o eu, em face de que o nível de angústia se eleva. O presente artigo objetiva colocar em discussão a política do aparecimento e desaparecimento das imagens na contemporaneidade e suas consequências clínicas. Resultado parcial de uma pesquisa que visa investigar a ascensão vertiginosa das imagens e o declínio da função das palavras na subjetividade contemporânea. Diante da angústia paralisante, impõe-se uma política da existência que remarque o lugar da singularidade a fim de que o sujeito do inconsciente apareça.
A PRESENÇA DO ANALISTA: LUGAR E FUNÇÃO DO CORPO DO PSICANALISTA EM DIFERENTES CONTEXTOS DE ATUAÇÃO
Authors: PRADO CAROLINA ESCOBAR DE ALMEIDA , ANJOS FABIO MENEZES DOS , ESTEVÃO IVAN RAMOS
Published: October 2021

RESUMO: Com base nas propostas de Freud e Lacan, visamos tratar do lugar e da função do corpo do analista como condições para a sustentação da clínica. Para isso, destacamos quatro diferentes contextos de atuação: o consultório; o trabalho nos dispositivos das redes de saúde e assistência psicossocial; o acompanhamento terapêutico e atendimentos online. Pensando a clínica psicanalítica em termos de tática, estratégia e política, encontramos que o ato analítico seria norteado pela ética da psicanálise e assegurado na sustentação da posição do analista enquanto presença - ponto de convergência que permite a inserção do psicanalista nos campos de atuação citados.
STELLA DO PATROCÍNIO E A METÁFORA DELIRANTE
Authors: ANGLADA CAROLINA
Published: October 2021

RESUMO: Em busca de saber se o insignificante pode ou não falar, este artigo se detém na poética proferida de Stella do Patrocínio, articulando os campos da psicanálise, da teoria da literatura e da filosofia. Discute-se, para tanto, o que é simbolizável no discurso delirante, e o que permanece à margem, impedido de ser interpretado totalmente. A metáfora, enquanto elaboração do Simbólico, norteia esta investigação, ao trazer para a discussão o pensamento estruturalista das figuras de linguagem, e uma orientação pós-estruturalista, que não toma a linguagem como código, mas como fluxo, a subverter a lógica da representação.
PAULO FREIRE: PRESENTE! LEVANTAMENTO BIBLIOGRÁFICO EM EDUCAÇÃO & SOCIEDADE
Authors: Almeida Luana Costa
Published: October 2021

RESUMO Com ampla produção, a obra de Paulo Freire é referência para diferentes pesquisadores do campo educacional. Parte da seção comemorativa do centenário do autor, o presente artigo se dedica a compreender sua presença na revista Educação & Sociedade, por meio de levantamento bibliográfico. Para tanto, consultamos os 41 volumes, publicados entre 1978 e 2020, localizando todos os textos que referenciaram Freire e sua obra. Além do mapeamento por ano e da catalogação das obras citadas, procuramos identificar os conceitos freireanos utilizados. Como resultado desse levantamento, destacamos dez dimensões conceituais, sendo os conceitos mais frequentemente empregados relacionados a “Pedagogia do oprimido/Libertação”, “Diálogo/Dialogicidade/Comunicação dialógica”, “Método Paulo Freire” e “Mudança/Transformação social”.
HISTOPATHOLOGICAL, CLINICAL AND EPIDEMIOLOGICAL FEATURES OF HEPATOPORTAL SCLEROSIS IN A REFERRAL CENTER FOR LIVER DISEASE IN NORTHEASTERN BRAZIL
Authors: ARAÚJO Caio , NUNES Vinícius Santos , SANTOS Genario , FREITAS Luiz Antônio Rodrigues de , SCHINONI Maria Isabel , PARANÁ Raymundo
Published: October 2021

ABSTRACT BACKGROUND: Hepatoportal sclerosis HPS or obliterative portal venopathy (OPV), one of the differential diagnoses for non-cirrohtic portal hypertension, is characterized by the disappearance of the portal branches, portal and septal fibrosis, perisinusoidal fibrosis and regenerative nodular hyperplasia (RNH). It is a spectral disease that may progress to severe portal hypertension. Its etiopathogenesis is still little understood, especially in Brazil, it has been probably misdiagnosed due to its histopatological similarities with the hepatosplenic form of schistosomiasis. OBJECTIVE: To analyze the profile of patients with HPS in Northeastern Brazil and to demonstrate the pathological characteristics of HPS. METHODS: We retrospectively analyzed cases of OPV in liver biopsies and explants from a referral center for liver in Bahia - Brazil. The qualitative and quantitative analysis of the portal tracts and liver parenchyma was made so that comparisons could be done among the HPS findings of our population and the findings described by other authors. RESULTS: From the 62 patients identified with HPS, 42% were male, while 58% were female. The average age at diagnosis was 48.3 years. From this group, we analyzed the liver biopsy of 10 patients whose diagnosis of schistosomiasis could be ruled out. From these 100% (10/10) presented dense portal fibrosis and portal venous obliteration. Liver parenchymal atrophy was present in 60% (6/10) of the patients, sinusoidal dilation was present in 30% (3/10), the presence of portal septa occurred in 50% (5/10) and dense portal fibrosis in all patients analyzed. Nodular regenerative hyperplasia was found in 30% (3/10) of the patients. CONCLUSION: HPS seems to be neglected and misdiagnosed in Brazil, due to its similarities with schistossomiasis. In our study dense portal fibrosis, obliteration of the portal vein branches, parenchymal atrophy, sinusoidal dilatation and parenchymal nodular hyperplasia were the main histopathological findings and were similar to that described in other countries.
Graduation of term assurance data using frailty approach
Authors: Onchere Walter Omonywa , Weke Patrick Guge , Ottieno Joseph Makoteku , Ogutu Carolyne Adhiambo
Published: October 2021

Frailty models have been used in literature to account for heterogeneity among insureds in-terms of mortality. In this article, we compare the gamma and the non-central gamma as frailty distributions with the exponentiated exponential and exponentiated Weibull as baseline hazards. We adopt a fully Bayesian approach to calibrate the baselines based on crude mortality rates from a major Kenyan insurer. Comparing the gamma-exponentiated Weibull with the non-central gamma-exponentiated Weibull models shows that the non-central gamma provides a good fit to the real life data-set and is therefore recommended for valuation.
Guarapiranga and Burle Marx Parks
Authors: Brito Edmilson Nazareno , Nascimento Ana Paula Branco do
Published: October 2021

Studies on the population’s perception towards urban green areas can contribute to the management of these spaces. This study analyzed the perception and use of two urban parks by their regulars. The regulars’ individual characteristics were identified and categorized according to the activities taking place in the parks, in order to characterize the uses that the population makes of these spaces. The data survey was accomplished by means of 103 interviews in each park, following a structured guideline that allowed the quantitative analysis of the data thus obtained. These parks are perceived and used for providing social and environmental functions, besides leisure and health benefits, thus contributing to the quality of life. The basic infrastructure, such as toilets and drinking fountains, and physical exercise facilities, such as multisport courts, playgrounds and hiking trails, are perceived as important for the social life of regulars of various age groups.
SNARE-seq2 v2
Authors: Plongthongkum Nongluk , H Diep Dinh , Chen Song , Lake Blue , Zhang Kun
Published: October 2021

To study the heterogeneity of complex tissues by joint profiling of gene expression and its regulation, we require an accurate and high-throughput method. Here we described improved high-throughput combinatorial indexing-based single-nucleus chromatin accessibility and mRNA expression sequencing 2 (SNARE-Seq2) co-assay. This protocol involves fixing and permeabilizing the nucleus followed by tagmentation, chromatin barcode ligation, reverse transcription, pooling and splitting for the next rounds of cell barcode ligation into cDNA and accessible chromatin (AC) on the same nucleus. The captured cDNA and AC are co-amplified before splitting and enrichment into single-nucleus RNA and single-nucleus AC sequencing libraries. The protocol can also be applied to both nuclei and whole cells to capture mRNA in the cytoplasm. This improvement allows us to generate hundreds of thousands of data set of each assay and can be scaled up to half a million cells from a single experiment. The entire procedure can be complete in 3.5 d for generating joint single-nucleus RNA and single-nucleus ATAC sequencing libraries.
Diffuse non-toxic goiter and pregnancy
Authors: Potine V. V. , Loginov А. В. , Tkathenko N. N.
Published: October 2021

The aim of this study was to investigate of effect of pregnancy on the thyroid sizes and function at the patients with diffuse non-toxic goiter in a region of marginal iodine deficiency. Materials and methods: 132 pregnant women in the age of 18-39 years, including 110 with diffuse non- toxic goiter and 22 pregnant women with a normal thyroid gland, were examined. 30 patients with diffuse non-toxic goiter of the first degree received 200 мкг per day of KI (iodid- 200), 40 patients with diffuse non-toxic goiter of the second degree received a 25-75 micrograms/day thyroxine (euthyrox). 25 patients with diffuse non-toxic goiter had not received regular therapy. The autoimmune thyroiditis is revealed for 15 women with diffuse non-toxic goiter. They received a 75-100 micrograms/day euthyrox. We estimated volume of the thyroid gland by ultrasound, serum TSH and serum thyroid hormone in each trimester of pregnancy. Results: At the healthy women during pregnancy the percentage increase of volume of a thyroid gland has constituted 24,30,2%. At the patients with diffuse non-toxic goiter, not receiving therapy, the thyroid gland was authentically increased at 37,11,1%. At the pregnant women receiving iodidum the percentage increase of volume of a thyroid gland has constituted 12,30,7%. After of a euthyrox therapy there was a relative decrease of the thyroid volume by 13,70,5%. In the group of healthy women a TSH level has increased inconsiderable from l,30,6mU/l to l,60,2mU/l to the end of pregnancy. During pregnancy in the group of women with diffuse non-toxic goiter without treatment rising the TSH values in a blood from l,40,3mU/I to 2,30,2 mU/l was revealed. The mean TSH levels of the goitrous pregnant group, receiving iodidum, essentially did not vary during pregnancy. In the goitrous pregnant group, receiving euthyrox, a TSH level has decreased considerably from l,80,5mU/l to 0,60,2 mU/l to the end of pregnancy. TSH values and free T4 in all the pregnant women were within the reference range in a blood of the healthy nonpregnant women. Was not observed of differences of pregnancy course and term delivery in compared groups. The high frequency of complications of pregnancy is connected to availability of the not diagnosed autoimmune thyroiditis. Conclusion: These results recommend to usage of iodine at the women with a not enlarged thyroid gland and with diffuse non-toxic goiter of the first degree and nonsupressic doses of thyroxine at the women with diffuse non-toxic goiter of the second degree during pregnancy.
Reproductive women health working at the gold extracting enterprises under conditions of chronic intoxication with cyanide compounds
Authors: Rukavishnikov V. S. , Kolycheva I. V.
Published: October 2021

The presence of high air concentrations of hydrogen cyanide vapours in the workplace, the exposure of which stipulates high morbidity rates with a temporary work capacity loss, complications of pregnancy development and births, working losses while nursing the sick children in the women workers of the factories above compared with a control group was found to be a feature of work conditions at the Gold Extraction enterprises. Pathogenetic links of chronic exposure to hydrogen cyanide which lead to reproductive health disturbances may be considered to be forming the picture of hystooxical hypoxia, detoxication mechanisms based on binding CN-ions with methemoglobin, thiocyanate cumulation, hormone T3 and T4 synthesis disturbances.
150-th Anniversary of the Birth of Dmitry Oskarovich Ott
Authors: Tsvelev Y. V. , Simchera I. А.
Published: October 2021

The ceremonial meeting of the scientific society of obstetricians and gynecologists of St. Petersburg and the Leningrad region, dedicated to the 150th anniversary of the birth of Professor Dmitry Oskarovich Ott, "made to respect Russian gynecology far beyond the borders of our Motherland, whose glorious name is known throughout the cultural world ..." ( V.S.Gruzdev), took place on his birthday - February 24.
Lipoperoxidation and antioxidizing system at the pregnant women at uncomplicated pregnancy and placental insufficiency
Authors: Florensov V. V. , Protopopova N. V. , Kolesnikova L. I.
Published: October 2021

The biochemical investigations of blood serum in 27 women with physiological current of pregnancy and 74 pregnant women with placental insufficiency were carried out with the aim of study the role of lipoperoxidation and antioxidative system in maintenance of adaptation processes at these conditions.
Gynecology. Textbook for universities, edited by G.M. Savelieva, V.G. Breusenko
Authors: Gaidukov S. N.
Published: October 2021

The need for new textbooks arises at regular intervals with an interval of about five years. The appearance in the university library of a new textbook is each time perceived with interest and enthusiasm, both by teachers and students, since there is an opportunity to take a new step following the improvement of knowledge and the emergence of new technologies
The development of cities supported by communication and information technologies
Authors: Machado Júnior Celso , Ribeiro Daielly Melina Nassif Mantovani , Viana Adriana Backx Noronha , Furlaneto Cristiane Jaciara
Published: October 2021

This research aims to analyze the relationship between economic, social and digital performance in cities of different sizes in Brazil. Data provided by the following official agencies: National Treasury Secretariat, National Mayors' Front and Risk Classification Agency were used. Pearson's correlation was used to identify the influence of digital, social, and economic performance variables in cities divided into groups based on the number of inhabitants. There was a strong correlation between Communication and Information Technologies and social and economic aspects. The greater the needs of cities, the more intense is the use of Communication and Information Technologies, reinforcing the establishment of the perspective of smart cities.
Detection performance characteristics of the digital undersampling receiver
Authors: Smolyakov A.V. , Podstrigaev A.S.
Published: October 2021

Multichannel digital receivers based on the signal processing technology involving undersampling are used for the instantaneous wideband analysis of the electronic environment. One of the most common algorithms for measuring input signal’s carrier frequency in such receivers includes unfolding of the signal’s spectrums from the first Nyquist zone of all receiver’s channels to the single frequency axis and searching for the frequency where the spectrum components from all of the receiver’s channels coincided. Performance of the signal detector, which uses this algorithm in its operation, was not studied. In the absence of a mathematical description of such a detector, evaluating the digital undersampling receiver’s sensitivity becomes possible only in the late stages of prototyping when it can be done through experimental study. Additionally, it is impossible to set a detection threshold in the receiver according to the Neyman-Pearson criterion, which hardens building constant false alarm rate (CFAR) systems based on this type's receivers. This paper aims to develop the mathematical description of the digital undersampling receiver's detector and then, using this model, to get expressions and computer models to evaluate the characteristics of such receiver even in early stages of its development. This paper's main result is the developed mathematical tools necessary to evaluate the multichannel digital undersampling receiver’s signal detector performance. It is shown that the false alarm probability in such a detector does not exceed some value no matter how small the detection threshold is. The expression for evaluating the maximum false alarm probability by the receiver’s parameters is also presented in the paper alongside the true positive rate plots as a function of signal-to-noise ratio for the three-channel receiver. These results can be used in evaluating the digital undersampling receiver’s characteristics in the early stages of its development. It allows one to choose optimal values of the receiver’s parameters which are hard and expensive to change after prototyping is done, and there is an opportunity to evaluate the receiver’s characteristics experimentally. Moreover, the obtained mathematical expressions make it possible to set the receiver's detection threshold according to the Neyman-Pearson criterion and build on its base a CFAR-systems widely used for wideband signal analysis.
Rich feature hierarchies for accurate object detection and semantic segmentation
Authors: Virasova A.Y. , Klimov D.I. , Khromov O.E. , Gubaidullin I.R. , Oreshko V.V.
Published: October 2021

Formulation of the problem. Over the past few years, there has been little progress in object detection techniques. The most efficient are complex computational ensemble methods, which usually combine several low-level image properties with high-level properties. However, every day interest in artificial intelligence is growing, and the idea of using neural networks on board a spacecraft, with the possibility of making decisions and issuing one-time commands, is very promising, since it makes it possible to analyze a large data stream in real time without resorting to ground station, thereby not losing information when transmitting a packet. The purpose of the work is to conduct research on the possibility of effective use of modern models of neural networks, to develop a methodology for their use in the problem of object detection and analysis of the element base for hardware implementation with the possibility of using convolutional neural networks for thermovideotelemetry on board a spacecraft. Results of work. An approach has been formulated that combines two key ideas: 1) application of high-throughput convolutional neural networks for downward processing of image regions in order to localize and segment objects; 2) preliminary training for the auxiliary task, followed by fine tuning of the domain, which gives a significant increase in performance in the case when the training data is insufficient. The analysis of the element base for the possibility of hardware implementation of neural networks on board a spacecraft using electrical radio products of domestic and foreign production is carried out. Practical significance. The efficiency of preliminary network training for an auxiliary task is shown, followed by fine tuning of the subject area. A technique is described that makes it possible to increase the average accuracy of detecting objects in an image by more than 30%. The analysis of the existing element base, the possibility of hardware implementation of neural networks on board the spacecraft using electrical radio products of domestic and foreign production, as well as the criteria for selecting key elements.
LOS NIÑOS DE MORELIA
Authors: Navarrete Torres María del Carmen
Published: October 2021

En 1937 llegaron a la ciudad de Morelia 456 niños españoles. Venían con una maleta en la mano y la promesa de regresar con sus padres en cuanto terminara la Guerra Civil, misma que pensaban que ganaría la causa republicana. Pero la guerra se perdió y los niños envejecieron solos, lejos de casa
Los niños de Morelia, es un estudio sobre los primeros refugiados españoles en México, que pertenece a la Colección Divulgación de la serie « Testimonios» y fue editado por el Instituto Nacional de Antropología e Historia. La autora Dolores Pla Brugat, es Doctora en Historia por la Facultad de Filosofía y Letras de La Universidad Autónoma de México. Además es miembro del Sistema Nacional de Investigadores.
TEMAS SELECTOS DE COMERCIO ELECTRÓNICO
Authors: Rodríguez Garza Carlos Alberto
Published: October 2021

RESUMEN

Este documento presenta una serie de temas que han salido de estudios realizados sobre el comercio electrónico. Se analizan las ventajas y desventajas resaltando que éstas últimas pueden ser minimizadas. Del mismo modo se presentan algunos aspectos importantes del comercio electrónico como su uso en las PYMES. Asimismo, se descubre que este tipo de comercio no consiste únicamente en contar con una página web, sino que más bien debería seguir un proceso de adopción más que de adaptación.

ABSTRACT

This document presents a number of issues that have come from studies on electronic commerce. The advantages and disadvantages are analyzed highlighting that the latter can be minimized. Similarly some important aspects related to the electronic commerce are shown, especially when used in the SMEs. Also it is found out that this type of business must not rely solely on a Web page. On the contrary, it is suggested to follow a process of adaptation rather than adoption.
LA SEGURIDAD SOCIAL: ANÁLISIS DE SU PROBLEMÁTICA Y PROPUESTAS DE MEJORA
Authors: Izar Landeta Juan Manuel , Ynzunza Cortés Carmen Berenice
Published: October 2021

RESUMEN

El número creciente de trabajadores a punto de retirarse presenta un problema serio para los sistemas de seguridad social en todo el mundo. Esto debido a que se estima que dichos programas se verán faltos de fondos en los próximos años.
Este ensayo comenta algunas de las variables más importantes relacionadas con esta temática. Estas incluyen la edad de retiro, el manejo financiero de las cuentas de retiro y esquemas flexibles de jubilación, entre otros.
También se incluyen algunas recomendaciones prácticas para solventar este problema.

ABSTRACT

The increasing number of workers approaching retirement age poses a challenge to social security programs all around the world. This is because these programs are projected to get underfunded in the coming years.
This essay comments some of the most important variables involved in such an important topic. These include retirement age, financial management of retirement accounts and flexible retirement schemes, amongst others.
Several practical recommendations to solve this problem are included.
LA CIUDAD DEL CONOCIMIENTO
Authors: Piña Gutiérrez José Manuel
Published: October 2021

En la actualidad, la sociedad se encuentra viviendo etapas de grandes cambios de tipo económico, político y social y es la economía fundamentada en el conocimiento lo que ha originado que empiece a existir la iniciativa de la Ciudad de Conocimiento, la cual consiste en un espacio geográfico en donde, de acuerdo a un plan y una estrategia que asumen tanto sociedad, universidad y gobierno, las personas tienen el propósito común de construir una economía basada en el desarrollo del conocimiento, la cual se basa tres elementos importantes: desarrollo cultural, social y económico, para que así pueda consolidarse el conocimiento sustentable, toda vez que sus habitantes son creativos y poseen instrumentos para hacer accesible el conocimiento a todos los niveles de la sociedad; así mismo, cada espacio y recursos, son considerados una oportunidad para el desarrollo del conocimiento y la innovación tecnológica, ya que la clave está en el capital humano. La riqueza de las naciones se genera por el conocimiento, lo que repercute en las nuevas tecnologías, por eso es tan importante la capacitación continua.
APLICACIÓN DEL QFD A LA INDUSTRIA REFRESQUERA DE SAN LUIS POTOSÍ, MÉXICO
Authors: Izar Landeta Juan Manuel , Ynzunza Cortés Carmen Berenice
Published: October 2021

RESUMEN
Objetivo: Mostrar cómo el despliegue de funciones de calidad (QFD), herramienta para la planeación y solución de problemas, puede ser utilizada en la industria refresquera para explorar los requerimientos técnicos y el nivel de satisfacción de los clientes con los atributos ofrecidos en el producto.
Material y Método: El enfoque propuesto de la metodología del QFD, utiliza la casa de la calidad, en la cual se considera no sólo los aspectos inherentes a las relaciones entre los requerimientos del cliente y las características del producto, sino también las correlaciones entre las características de éstos y sus procesos. Para demostrar la utilidad del QFD, se toman como referencia 4 marcas de refrescos ofertadas en el Estado de San Luis Potosí. En el estudio los clientes dan su opinión sobre el producto analizado, respondiendo a una encuesta, y del mismo modo, los fabricantes de refrescos expresan su opinión a través de una entrevista personal.
Resultados: Los resultados alcanzados permiten determinar las características técnicas más importantes para el cliente, así como de los procesos del embotellado de refrescos para garantizar la satisfacción de sus clientes, mostrando así la utilidad que la aplicación del QFD tiene como herramienta para la mejora continua y dar un enfoque de orientación al cliente.

ABSTRACT
Objective: This research aims to show how the quality function deployment (QFD), tool for planning and problem solving, can be used in the soft drink industry to explore the technical requirements and level of satisfaction of consumers with the attributes offered by product.
Material and Method: The approach proposed by the QFD methodology, uses the house of quality, which considers not only the aspects inherent in the relationship between customer requirements and product characteristics, but also the correlations between their characteristics and their processes. To demonstrate the utility of QFD, 4 soft drink brands that are offered in the state of San Luis Potosi are considered as reference. In the study, the customers give their own opinion regarding the analyzed product by answering a survey, and similarly, the soft drink manufacturers express their opinion through a personal interview.
Results: The given results in this study let to determine the most important technical soft drink characteristics for the client, as well as the soft drink bottling processes to guarantee customer satisfaction, showing in this way, the usefulness of applying the methodology of QFD as a tool for the product continuous improvement and customer orientation approach.
Educación a Distancia: El Nuevo Paradigma
Authors: Rodríguez Garza Carlos Alberto
Published: October 2021

Hoy en día la educación a distancia además de una nueva forma de enseñanza es una aproximación a los modos de producción simbólica, generando un salto importante para superar el paradigma educativo escuela/fábrica del que habla Sir Ken Robinson; al hablar sobre la mayoría de los sistemas educativos en el mundo, menciona están desfasados, son anacrónicos, están basados en un sistema de producción fabril, donde se buscaba la estandarización de los productos, todos iguales, por medio de la entrada de diferentes elementos de materia prima hacia la salida de productos de la misma característica que satisfacen un mercado no muy variado, esta similitud escuela/fábrica se puede observar con los elementos que se comparten entre ellos: timbre, formación en filas, paso de grado de acuerdo a la edad como en cadena de montaje y sobre todo el encontrar alumnos de diferentes características a los que se les enseña lo mismo e igual, con la idea de que todos al final salgan con los mismos conocimientos para un mercado laboral que así los requiere.
LA DUALIDAD DE LA MODERNIDAD, RIESGOS INEVITABLES DEL DESARROLLO TECNOLÓGICO
Authors: Aguiar Miramontes Jesús
Published: October 2021

REESUMEN
En este texto se presentan algunas definiciones para
entender el concepto de modernidad, así como varios
de los riesgos inherentes a ella. Con el desarrollo y
evolución de las sociedades han surgido nuevos retos a
los cuales ha sido difícil encontrar solución, por ejemplo,
el deterioro ambiental. Asimismo se argumenta que
la inevitabilidad con la que son vendidos los riesgos
del desarrollo y el progreso es y debe ser discutible,
sobre todo cuando se pone en peligro la existencia
de la humanidad.

ABSTRACT
In this paper some definitions to understand the concept
of modernity are shown, as well as several of the risks
inherent to it. With the development and evolution
of societies new challenges have emerged whose
solutions have been difficult to find, for example, the
environmental degradation. Here it is argued that the
inevitability with which the risks of development and
progress are sold is and must be debatable, especially
when it threatens the existence of mankind.