bluuebunny/crossref_metadata_2025 huggingface dataset:
Yogyakarta Urban Middle-Class Sufism: Economic, Political and Cultural Networks
Authors: Yusdani Yusdani , Sanaky Hujair AH , Safitri Edi , Machali Imam , Juliansyahzen Muhammad Iqbal
Published: June 2020

The phenomenon of strengthening religious activity in the urban middle-class society in Yogyakarta Special Region in the last decade has been remarkable. The shift from the traditional Sufism to the model of piety associated with this middle-class Sufism further reinforce the middle class's religiosity. This study focused on the problem of the middle-class Muslim community when involving in Sufi practices. Through an in-depth interview with Sufi members and observation on their Sufi practice, this study shows that the urban middle-class Sufism pattern in Yogyakarta places emphasis on aesthetic-symbolic values. On the one hand, the tendency of religious patterns of Muslim communities is a form of negotiation between the values of spirituality in Islam and the forms and practices of global culture. On the other hand, the Sufi practice constitutes negotiation of the models of piety with economic-business motives. This Sufism is not institutionalized in conventional Sufism, commonly known as sufi order (tarekat) such as qadariyya, naqshabandiyya, and shattariyya, among the most popular Sufi order. Middle-class Sufism frames their distinctiveness in the form of economic, political, and cultural networks.
Exploring the Integration-Interconnection Paradigm in the Indonesian Context of Community Education And Practice
Authors: Muchammadun Muchammadun
Published: June 2020

The paper explores the daunting question as to how the integration-interconnection paradigm is actualised in the context of academic disciplines in Indonesia. This is accomplished by specifically analysing its application, through a purposive sampling of previously published studies, to the field of community development. The subsequent conclusions reveal core features of the integration-interconnection paradigm and its historical roots, and their relevance for community education and development today. In supporting the integration-interconnection paradigm, the writer proposes that Rothman’s and Ann Jeffries’ revised community development model is suitable for modification to accommodate local community education and practice in Indonesia. The paper identifies three major findings from studies in this field and discusses their implications. Firstly, from the epistemological point of view, there is a growing belief that science and religion are able to engage in collaborative dialogue rather than exist in mutual isolation. This will ensure an enhanced understanding of human interaction within our social environment. Secondly, religion and spirituality may potentially contribute to establishing a shared-base for supporting ethical values for professional practice. The final finding is that community developers, working from these underpinning assumptions, are more likely to succeed in their goals through exploring participatory ways of community practice.
Contemplative and Transformative Learning for Character Development in Islamic Higher Education
Authors: Alimah Ade
Published: June 2020

Islamic higher education is supposed to develop Indonesians' characters due to its focus on teaching Islam. Moreover, the number of Islamic higher education institutions is vast, reaching 777. Indeed, their contribution to the character development of Indonesians may be significant. However, occurring religious-based prejudices and conflicts, as well as a high index of corruption, show the paradoxes and challenges of Islamic higher education. Although there has been no research demonstrating a statistically significant correlation between Islamic teaching and crime rate or moral issues, educators in Islamic higher education institutions should reflect on what should be done to enhance their leverage on character education. In this paper, two concepts of contemplative learning and transformative learning are discussed to find feasible ways of teaching Islam in the challenging contemporary world. Contemplative and transformative learning in character development requires educators to implement mindfulness and connectedness through integrating all entities of learners' cognition, emotion, intuition, and body, interrelating multi-disciplines, and connecting learning to the real world.
Islamic Education and Religiosity: Voices of the Indonesian Muslim Communities in Australia
Authors: Zulfikar Teuku , Emawati Emawati
Published: June 2020

Indonesian Muslims have made their presence in Australia since the 1970s. Some of them now have become citizens and others preferred to be permanent residents. As they have lived in Australia, in which Islam is not the dominant religion, they were concerned with their children’s religiosity. These Muslims attempted to teach Islam to their children in any way possible. This research, therefore aims at exploring Indonesian Muslims’ parents’ ways of teaching Islam to their children, and their children’s responses on their parents’ approaches in educating them Islam. Using in-depth interviews, the study unveiled that the parents used various aproaches. Their approaches were democratic, in which a great deal of dialogues and neggotiation took place. They also monitored their children’s attitudes and kept reminding them about Islam; setting the role models was also a significant approach used in teaching Islam to their children, and balancing the public schooling and the madrasah. The findings also revealed that these young Muslims recognized the significant role their parents have taken to teach them Islam and shape their religiosity and they were thankful for their parents although some dissenting views on several issues also emerged.
TOKOH UTAMA TAK BERPENGHARAPAN DALAM CERITA RAKYAT INDONESIA
Authors: Asri Iit Purnama
Published: June 2020

Penelitian ini bertujuan untuk menguak bagaimana tokoh utama yang tidak berpengharapan diceritakan dalam cerita rakyat Indonesia. Penelitian ini berfokus pada dua cerita rakyat dengan tokoh utama pria yang tidak rupawan yaitu Bujang Katak dari Bangka Belitung dan Si Bungsu Katak dari Pulau Kei. Dua karakter laki-laki utama dalam cerita dijelaskan melalui teori aktansial A. J. Greimas. Fokus dari penelitian ini adalah kesamaan objek dalam bentuk pernikahan dengan putri raja dan penentang yang berbeda yaitu persyaratan dari raja. Temuan dari penelitian ini meliputi: 1) Objek dari dua cerita adalah sama yaitu pernikahan dengan putri raja, yang berarti sumber kebahagiaan bagi pria adalah pernikahan; 2) Penentang pada kedua cerita yaitu persyaratan dari raja yang menunjukkan bahwa raja dan putrinya yang menikahi Bujang Katak dan Si Bungsu Katak adalah materialistis. Hal itu dapat dilihat dari persyaratan yang diajukan oleh raja bersifat sangat material dan sang putri tidak menolak persyaratan tersebut.
Ingestion et digestion chez les ruminants soumis à un stress de chaleur
Authors: MORAND-FEHR P. , DOREAU M.
Published: June 2020

Le stress de chaleur conduit généralement à des diminutions de la consommation alimentaire liées à la thermorégulation : l’animal cherche à réduire sa production de chaleur, due surtout aux fermentations dans le rumen. Les diminutions de consommation peuvent également s’expliquer par une disponibilité réduite de la végétation sur prairie ou sur parcours et par la dégradation de sa valeur nutritive, ainsi que, parfois, par une moindre disponibilité en eau de boisson. Lorsque le niveau d’ingestion est très faible, la digestibilité peut diminuer. En conditions contrôlées, l’effet isolé de l’augmentation de la température ambiante tend à améliorer la digestibilité de la ration de 0,2 point par degré Celsius à même niveau d’ingestion. Pour lutter contre les effets néfastes du stress de chaleur sur le niveau d’ingestion, le ruminant peut modifier son comportement alimentaire en pâturant aux heures les plus fraîches (la nuit), en multipliant les prises alimentaires et en réduisant leur durée. Il peut aussi modifier ses choix alimentaires, donc la composition de ce qu’il ingère réellement. Dans des conditions d’élevage plus intensif, il peut être intéressant de mettre des abris à la disposition des animaux, de les arroser, d’augmenter la concentration énergétique du régime, d’apporter une source d’azote fermentescible lorsque celle-ci est le facteur limitant de la digestion des fourrages, et d’augmenter le bilan cation-anion de la ration.
Les protéines de stress
Authors: DAVID J.C. , GRONGNET J.F.
Published: June 2020

Pour la survie des cellules, en particulier dans des conditions difficiles, l’un des mécanismes qui s’est le plus maintenu lors de l’évolution est celui de l’expression de protéines connues sous le nom de protéines de choc thermique, ou protéines de stress. Ces protéines assurent une protection lors d’un second stress et induisent ainsi une tolérance aux agressions qui suivent.
Trois grandes familles de protéines de choc thermique ont été décrites selon leurs tailles : 27 kDa, 70 kDa et 90 kDa. Ces protéines sont exprimées à la suite de toute situation qui compromet la survie cellulaire. Parmi ces situations se trouvent d’abord l’augmentation de température, l’exposition à des métaux lourds ou à d’autres agents chimiques comme l’ozone, l’hypoxie, l’anoxie, le manque de glucose ou les infections. Leur rôle consiste alors à protéger l’ensemble vital des protéines cellulaires. Cette protection s’effectue de façon préférentielle selon les tissus mais leur expression est fortement atténuée quand les cellules et tissus sont en phase de récupération après un premier stress. Ainsi, la réponse des protéines de choc thermique peut être considérée comme un mécanisme universel de défense contre toute forme d’agression. Mieux connaître la réponse des protéines de choc thermique à des agressions diverses chez les animaux domestiques peut amener à une meilleure connaissance de leur état de santé en général et de celle de la qualité de leur production.
Mesurer l’épaisseur de lard dorsal des truies pour définir leurs programmes alimentaires
Authors: DOURMAD J.Y. , ETIENNE M. , NOBLET J.
Published: June 2020

Pour optimiser les performances de la truie et sa longévité, il est important d’adapter régulièrement les apports alimentaires de façon à contrôler l’état des réserves corporelles et éviter ainsi les situations d’engraissement ou d’amaigrissement excessif, qui sont préjudiciables à de bonnes performances de reproduction. La gestation apparaît la période privilégiée pour reconstituer un niveau de réserves corporelles adéquat. Pour cela il est nécessaire de disposer de critères objectifs d’évaluation des réserves, de fixer des objectifs en fonction du stade physiologique et de traduire ces objectifs en termes d’apports nutritionnels. La démarche proposée consiste à évaluer les besoins énergétiques de la truie en gestation sur la base d’une approche factorielle prenant en compte l’importance des réserves à reconstituer, ces réserves étant évaluées à partir du poids vif et de l’épaisseur de lard dorsal mesurée aux ultrasons. Sur la base des informations obtenues expérimentalement ou en élevage, on peut retenir, pour des femelles croisées Large White x Landrace, un objectif d’épaisseur de lard dorsal (mesuré au niveau de la dernière côte à 6,5 cm de la ligne médiane) de 16 à 19 mm au sevrage et de 19 à 22 mm à la mise bas, quel que soit le numéro de portée, l’écart entre ces deux objectifs devant se situer entre 2 et 4 mm. En pratique, le plus important pour atteindre ces objectifs est de favoriser au maximum la consommation pendant la lactation, l’alimentation pendant la gestation servant seulement à corriger l’état des réserves.
Conservation des ’prions’ chez les Vertébrés
Authors: JOLY J.S. , NGUYEN V. , BOURRAT F.
Published: June 2020

Le terme prion a tendance à être utilisé pour désigner un nombre de plus en plus vaste de protéines souvent très divergentes. L’état actuel des connaissances permet de conclure à l’existence de ’prions’ potentiellement pathogènes chez les Mammifères uniquement. Des protéines de la même famille ont été trouvées chez les Oiseaux et les Tortues. Enfin, aucun homologue des ’prions’ n’a pu être mis en évidence chez les Poissons, en dépit de recherches approfondies. Une révision de la nomenclature de ces molécules semble donc s’imposer, à des fins de précision scientifique et d’information claire du public.
Production et composition du lait de brebis : effets de l’alimentation
Authors: BOCQUIER F. , CAJA G.
Published: June 2020

Le niveau d’alimentation est un des facteurs d’élevage qui affecte la production et la composition du lait chez la brebis laitière. La production laitière augmente avec le niveau d’alimentation et inversement, alors que les effets sur la composition du lait sont moins nets. Le taux butyreux du lait est généralement corrélé négativement au bilan énergétique des brebis, alors que le taux protéique est corrélé positivement avec celui-ci : un niveau d’alimentation élevé diminue généralement la teneur en matières grasses du lait et augmente légèrement la teneur en protéines. La distribution de grandes quantités de concentrés, qui est un moyen simple d’augmenter l’apport d’énergie dans la ration, risque de provoquer une chute des taux butyreux et protéique et, secondairement, entraîne une réorientation des flux d’énergie vers le dépôt de gras corporel. Lorsque la brebis n’a pas atteint son potentiel de production, l’augmentation de la teneur protéique de la ration augmente la production de protéines du lait, mais sans modification du taux protéique du lait.
L’utilisation de certains nutriments tels que les matières grasses ou les acides aminés protégés semble intéressante comme moyen d’accroître les teneurs en matières grasses et/ou protéiques du lait, mais peu d’expériences ont été effectuées sur brebis laitières et l’intérêt de ces nutriments est encore mal connu.
Dans les conditions pratiques d’élevage de brebis laitières, généralement alimentées en groupes, les effets de l’alimentation sont souvent masqués par d’autres facteurs d’élevage connus pour modifier eux-mêmes la composition du lait. Il est donc nécessaire de prendre en compte la variabilité individuelle (stade de lactation notamment) pour définir la stratégie d’alimentation qui permette de maîtriser la composition du lait collecté.
La leptine chez le poulet
Authors: CASSY S. , DRIDI S. , TAOUIS M.
Published: June 2020

Chez les volailles, le contrôle du bilan énergétique représente un enjeu économique majeur dans la mesure où la sélection des espèces aviaires sur la vitesse de croissance s’est accompagnée d’un développement excessif de l’engraissement. Connue chez les mammifères pour son action sur le contrôle de la prise alimentaire et de la dépense énergétique, la leptine pourrait également jouer un rôle important dans le contrôle du bilan énergétique des volailles. Chez le poulet, la leptine est exprimée dans le tissu adipeux mais surtout dans le foie. Cette expression hépatique est probablement à mettre en relation avec le rôle joué par cet organe dans la lipogenèse chez les volailles. Comme chez les mammifères, la leptine reflète l’adiposité du poulet et l’expression de la leptine peut être régulée par l’état nutritionnel ou la composition du régime alimentaire. La leptine inhibe la prise alimentaire en agissant probablement sur des récepteurs situés au niveau de l’hypothalamus. Modulée par de nombreuses hormones impliquées dans le contrôle de la prise alimentaire et des réserves énergétiques, les effets de la leptine chez le poulet semblent être similaires à ceux décrits chez les mammifères.
Les ruminants domestiques de la Caraïbe : le point sur les ressources génétiques et leur exploitation
Authors: NAVES M. , ALEXANDRE G. , LEIMBACHER F. , MANDONNET N. , MENENDEZ-BUXADERA A.
Published: June 2020

La Caraïbe a été peuplée par les espèces de ruminants domestiques à partir du XV ème siècle. Après les premières introductions de bétail ibérique, des apports variés ont occasionné de nombreux métissages. Ils ont pu être plus ou moins importants, allant jusqu’à l’utilisation de croisements systématiques se substituant aux populations Créoles d’origine. Des populations locales variées et originales se maintiennent, malgré des apports récents liés aux échanges commerciaux et aux progrès des méthodes modernes de reproduction.
Ces populations animales contribuent fortement à l’élevage de la région, principalement dans des systèmes de production traditionnels ou familiaux où leurs qualités d’adaptation sont appréciées. Malgré leur faible spécialisation, elles révèlent également des aptitudes intéressantes de production. Elles constituent également un matériel biologique modèle pour l’étude de caractères d’adaptation, comme la résistance à certaines pathologies tropicales.
Peu d’actions ont été mises en œuvre pour la conservation ou la gestion des populations locales dans la Caraïbe. Elles concernent principalement les Grandes Antilles, où quelques troupeaux d’animaux Créoles subsistent, mais aussi des races synthétiques de constitution plus récente et fortement organisées. Dans les Petites Antilles, seuls les départements français proposent une gestion des races locales in situ, avec des programmes de sélection concertés.
Avec des effectifs réduits et dispersés, la Caraïbe rassemble de nombreuses ressources génétiques locales méconnues et peu exploitées. Des travaux récents relancent l’intérêt pour ces ressources, au sein de systèmes d’élevage durables. La mise en place d’une stratégie globale de gestion de ces populations dans la Caraïbe et l’Amérique Latine devrait renforcer les efforts des différents partenaires dans ce sens.
Acides aminés digestibles dans l’intestin. Origines des variations chez les ruminants et répercussions sur les protéines du lait
Authors: RULQUIN H. , VÉRITÉ R. , GUINARD-FLAMENT J. , PISULEWSKI P.M.
Published: June 2020

La production de protéines (lait, viande, laine, poil) des ruminants peut être limitée par des apports insuffisants en certains acides aminés (AA) appelés pour l’occasion AA limitants. En effet, contrairement à ce qui était généralement admis, la composition des acides aminés digérés par les ruminants n’est pas constante. Si la part des protéines microbiennes et leur composition en AA relativement constante tamponnent les variations de la composition en AA des contenus intestinaux, celle-ci varie en fonction de la composition en AA de la ration et de sa richesse en protéines peu dégradables. L’importance des conséquences des variations de la composition en AA des contenus digestifs sur la production de protéines du lait a été étudiée grâce à des apports postruminaux de doses croissantes d’un acide aminé. La supplémentation postruminale en lysine ou en leucine peut faire gagner jusqu’à 4 g/kg de taux protéique. Le gain maximum n’est que de 2 g/kg avec la méthionine, l’histidine, la phénylalanine et la thréonine. Dans tous les cas l’augmentation du taux protéique porte sur le taux de caséine. En milieu de lactation, l’histidine et la thréonine accroissent aussi le volume de lait produit de façon dose-dépendante.
Construction of an Exposure-Pathway-Phenotype in Children with Depression due to Transfusion-Dependent Thalassemia: Results of (Un)supervised Machine Learning
Authors: Al-Hakeim Hussein , Najm Asawer , Moustafa Shatha , Maes Michael
Published: June 2020

Transfusion dependent thalassemia (TDT) patients are treated with continued blood transfusions and show a higher prevalence of depression. TDT with consequent iron overload and inflammation is associated with increased severity of depressive symptoms in TDT children.Aim of the study: To construct a pathway-phenotype which combines iron overload and neuro-immune biomarkers with depressive symptom subdomains in TDT children.Methods: We measured iron status parameters (iron, ferritin, transferrin saturation percentage) and inflammatory (interleukin-1β and tumour necrosis factor-α) biomarkers in TDT (n=111) and healthy (n=53) children and analyzed the results using machine learning.Results: Cluster analysis separated TDT children with depression from those without depression and revealed two depressive subgroups one with low self-esteem and another with increased social-irritability scores. Exploratory factor analysis validated four depressive symptom dimensions as reliable constructs, namely key depressive, physiosomatic, lowered self-esteem and social-irritability dimensions. Partial Least Squares showed that 73.0% of the variance in a latent vector extracted from those four clinical subdomains, immune-inflammatory and iron overload biomarkers was explained by exposure variables including the number of blood transfusions and hospitalizations and use of deferoxamine. The exposure data, iron and immune biomarkers, and symptom subdomains are reflective manifestations of a single latent trait, which shows internal consistency reliability and predictive relevance.Conclusions: The nomological network combining exposure, pathways and behavioral phenome manifestations provides an index of overall severity and disease risk and, therefore, constitutes a new drug target, indicating that iron overload and immune activation should be targeted to treat depression due to TDT.
SH-SY5Y-derived Neurons: A Neuronal Model System for Investigating TAU Sorting Mechanisms and Neuronal Subtype-specific TAU Vulnerability
Authors: Bell Michael , Zempel Hans
Published: June 2020

The human-derived SH-SY5Y neuroblastoma cell line is widely used for studying TAU physiology and TAU-related pathology in Alzheimer’s disease (AD) and related tauopathies. SH-SY5Y cells can be differentiated into neuron-like cells (SH-SY5Y-derived neurons), which resemble noradrenergic, dopaminergic or cholinergic neurons, by using various substances. This review evaluates whether SH-SY5Y-derived neurons are a suitable model for investigating intracellular TAU sorting mechanisms in general, and with respect to neuron subtype-specific TAU vulnerability. SH-SY5Y-derived neurons show pronounced axodendritic polarity resembling neuronal cell polarity, high TAU protein levels, axonal TAU localization, expression of the six major human brain isoforms, and TAU phosphorylation similar to AD. This enables studying the isoform- and phosphorylation-dependent impact on TAU subcellular distribution and axodendritic trafficking of TAU. As SH-SY5Y cells are accessible for genetic engineering, stable transgene integration and leading-edge genome editing are valuable and often-used tools for TAU-related research in these cells. Furthermore, SH-SY5Y-derived neurons resemble cells of distinct subcortical nuclei, i.e. the Locus coeruleus (LC), Nucleus basalis (NB) and Substantia nigra (SN), depending on the used differentiation procedure. This allows to study neuron-specific TAU isoform expression and intracellular localization in the context of vulnerability to TAU pathology. Limitations are e.g. the lack of mimicking age-related tauopathy risk factors and the difficulty to define the exact neuronal subtype of SH-SY5Y-derived neurons. In brief, this review discusses the suitability of SH-SY5Y-derived neurons for investigating TAU sorting mechanisms and neuron-specific TAU vulnerability in human-like conditions.
MADRASAH EDUCATION SYSTEM PROTOTYPE OF CHARACTER EDUCATION MODEL (Case Study at MTs and MA Assalam Kudus 2018)
Authors: Supaat Supaat , Taufikin Taufikin
Published: June 2020

The issue of character education in Indonesia needs to be handled professionally from effective planning, implementation and supervision. This case study using qualitative approach with the phenomenology inductive to find a model of character education in MTs and MA NU Assalam. The technique of collecting data is done by interviews, observation and documentation. Data is analyzed through stages data collection, data reduction, data display and conclusion. The results of this study indicate that: (1) the concept of character education in Assalam MTs and MA NU is based on environmental integration by developing academic religious characters namely religious, sincerity, exemplary, and loving the goodness of honesty, discipline, responsibility, communicative, and self control ( 2) System character education planning is based on a systemic-integrative model. The system is implemented in a way formation of a conducive environment (bi'ah), habitualization (habituation), personification, a model of a person's kyai (role model) behavior, integration of extracurricular and intra-curricular activities and programs. The surveillance system uses internal control management through system orderly and book attitude , and external through home visit . Based on the results of this study, it is a concept in the form of a character education model based on environmental integration, Role Model, personification, and habitualization.
Grand Design Instrument of Potential Abilities for Placement Test
Authors: Sutrisno Sutrisno , Wisudawati Asih Widi
Published: June 2020

This research aims to develop potential ability instruments for placement tests in graduate degrees. This study used the research and development instrument made by Hambleton and Jones sequences. The potential abilities measured by the instrument are academic potential and language skills. The product was reviewed by professional assessor and used in admission for selection in the academic years 2016/2017. The professional assessor reviewed the content, test construction, and language aspect. The construct and content validity from the professional assessor reached a good level with minor revision for the next selection. Ultimately, the results of the reviewing process are the potential academic test must not measure prior knowledge but the initial potential of the candidate and test for language should be emphasized on prior knowledge for Islamic study.
Implementation of Islamic Education Mentoring Programs at SMA Mujahidin Pontianak
Authors: Nugraha Muhamad Tisna
Published: June 2020

This article aims to investigate implementation of Islamic Education Mentoring program in SMA Mujahidin Pontianak. The research method used was qualitative-descriptive. The results of program implementation are: First, the implementation of the Islamic Religious Education mentoring program in SMA Mujahidin Pontianak was carried out through three stages, namely planning, implementation and evaluation. Second, several factors supporting the implementation of Islamic Religious Education mentoring programs include the active role of the Principal, educators and education personnel as well as the involvement of Rohis and the inhibiting factors are the lack of time to organize activities, limited resources, and the large amount of financial expenditure from the plan. This budget deficit causes the mentoring program run not optimally as it should be like the implementation of rihlah (religious tourism). The last probem was an unavailability PAI mentoring module for participants.
Multi-Kompetensi Perpustakaan dalam Mendukung Pembangunan Nasional
Authors: Fatmawati Endang
Published: June 2020

Untuk mewujudkan tujuan pembangunan berkelanjutan dibutuhkan kesiapan semua bidang, termasuk perpustakaan beserta pustakawannya. Pustakawan yang memiliki multi-kompetensi menjadi syarat untuk dapat berperan dalam mendukung pembangunan nasional. Pustakawan dikatakan mempunyai multikompetensi jika memiliki kemampuan yang bervariasi, baik berupa pengetahuan, sikap, maupun keterampilan sehingga mampu menjalankan tugas kepustakawanan dan tugas lain dengan baik. Selain kompetensi profesional dan kompetensi sosial, multikompetensi yang harus dimiliki pustakawan dalam mendukung pembangunan nasional adalah kompetensi hard dan soft, teknologi informasi dan komunikasi, kecerdasan, literasi media, dan literasi informasi.
Analisis Informasi Paten Balitbangtan Bersertifikat
Authors: Buhary Mumuh Muhamad , Andriani Juznia
Published: June 2020

Pengkajian bertujuan untuk menganalisis jumlah paten bersertifikat (granted) Badan Penelitian dan Pengembangan Pertanian (Balitbangtan) tahun 1999–2016. Aspek yang dikaji meliputi jumlah paten, jumlah unit kerja pemilik paten, jumlah penemu paten, perbandingan jumlah dan penemu paten, serta jumlah rata-rata klaim per paten. Objek pengkajian adalah dokumen paten Balitbangtan tahun 1999–2016. Pengkajian bersifat deskriptif dengan teknik pengumpulan data melalui studi literatur dan penelusuran dokumen paten di database Hak Kekayaan Intelektual (HKI) Balitbangtan. Penelusuran informasi paten menggunakan kata kunci berdasarkan unit kerja. Hasil penelusuran disajikan dalam bentuk tabel dan penjelasan deskriptif. Hasil kajian menunjukkan terdapat 107 dokumen paten Balitbangtan bersertifikat pada tahun 1999–2016. Paten terbanyak dihasilkan pada tahun 2016 dan BBP Mektan merupakan unit kerja Balitbangtan penghasil paten terbanyak (11 paten). Sebagian besar penemu paten adalah laki-laki (205 penemu) dan perempuan 77 penemu. Jumlah klaim setiap paten terbanyak terdapat pada tahun 2016, yakni 140 klaim, dan jumlah klaim paling sedikit pada tahun 2002, 2004, dan 2005,
masing-masing satu klaim. Sementara jumlah rata-rata klaim per paten tertinggi terdapat pada tahun 2016 (5,83 klaim per paten), dan paling rendah pada tahun 2002, 2003, 2004, dan 2005, masing-masing satu klaim per paten.
Kajian Bibliometrik terhadap Karakteristik Kepengarangan dan Artikel Pada Buletin Pertanian Perkotaan
Authors: Savitri Sheila
Published: June 2020

Untuk mengakomodir kebutuhan peneliti dan penyuluh dalam mengembangkan profesinya, BPTP Jakarta menerbitkan Buletin Pertanian Perkotaan yang telah terbit selama enam tahun, yaitu sejak 2011-2016. Kajian ini bertujuan untuk mengetahui sebaran profesi penulis, distribusi sebaran subyek, distribusi sebaran artikel, kemuktahiran sitiran literatur, distribusi sumber sitiran, tingkat kolaborasi penulis, hingga produktivitas penulis. Pengkajian dilakukan pada Buletin Pertanian Perkotaan dengan periode terbit 2011-2016, dengan menggunakan metode analisis bibliometrika, dan menggunakan rumus Subramanyam untuk menghitung tingkat kolaborasi penulis. Selama periode terbit 2011-2016, Buletin Pertanian Perkotaan telah meterbitkan 56 artikel dari 46 penulis, baik yang berasal dari dalam BPTP Jakarta maupun di luar BPTP Jakarta. Penulis artikel terbanyak pada buletin adalah penulis yang berprofesi sebagai peneliti, yaitu sebanyak 25 orang dengan rincian 19 orang peneliti BPTP Jakarta dan 6 orang peneliti dari luar BPTP Jakarta. Subyek yang membahas mengenai budidaya pertanian menduduki urutan teratas, yaitu sebanyak 25 artikel. Selama kurun waktu 2011-2016, distribusi sebaran artikel terbanyak terdapat pada tahun 2013-2015, yaitu masing-masing sejumlah 10 artikel. Namun, untuk kemutakhiran sitiran masih perlu diperbaiki. Mengacu pada Pedoman Karya Tulis Ilmiah pada yang Peraturan Kepala Lembaga Ilmu Pengetahuan Indonesia Nomor 04/E/2012, pustaka acuan yang terdapat dalam artikel-artikel di buletin mayoritas merupakan terbitan di atas 5 tahun, yaitu sebanyak 701 artikel. Sedangkan menurut aturan tersebut, kemutakhiran pustaka acuan harus berusia 5 tahun ke bawah. Untuk persentase kemuktahiran sitiran artikel berdasarkan subyek diketahui artikel bersubyek sosial ekonomi pertanian mayoritas sitiran berasal dari artikel terbitan di bawah 5 tahun (43%). Sedangkan artikel bersubyek pascapanen mayoritas didominasi oleh artikel terbitan di atas 10 tahun (43,8%). Untuk distribusi sumber sitiran, sumber pustaka acuan yang berasal dari majalah ilmiah baru di angka 46,5%, angka tersebut masih jauh di bawah ketentuan yang ditetapkan oleh LIPI, yaitu sebanyak 80%. Hal ini mengindikasikan bahwa para penulis masih membutuhkan informasi-informasi terbaru mengenai penelitian yang akan dituangkan karya tulis ilmiahnya sebagai sumber pustaka acuan, terutama yang berasal dari literature sekunder. Oleh karena itu, pustakawan harus berperan aktif sebagai penyedia informasi yang muktahir. Tingkat kolaborasi penulis, berdasarkan rumus Subramanyam, diperoleh angka 0,845, dimana angka tersebut menunjukkan bahwa hasil penelitian pada bidang tersebut lebih banyak dilakukan secara berkolaborasi. Hal ini juga dapat menunjukkan sebagai wujud tanggung jawab peneliti senior dalam membina peneliti yang berada di bawahnya. Produktivitas penulis tertinggi dicapai oleh Yudi Sastro dengan menyumbang 21 artikel selama kurun waktu terbitan 2011-2016.
Resistencia a insecticidas en Aedes aegypti y Aedes albopictus (Diptera: Culicidae) de Tapachula, Chiapas, México
Authors: López-Solís Alma Delia , Castillo-Vera Alfredo , Cisneros Juan , Solis-Santoyo Francisco , Penilla-Navarro Rosa Patricia , Black IV William C , Torres-Estrada José Luis , Rodríguez Américo David
Published: June 2020

Objetivo. Determinar la resistencia a insecticidas en Ae. ae­gypti y Ae. albopictus de Tapachula, Chiapas, México. Material y métodos. Se utilizaron ovitrampas para obtener huevos de mosquitos Aedes y se realizaron pruebas de susceptibilidad (CDC) y ensayos enzimáticos con la primera generación. Resultados. Aedes aegypti mostró resistencia a deltametri­na, permetrina, malatión, clorpirifos, temefos y a bendiocarb (CARB), mientras que Aedes albopictus a malatión y en me­nor grado a cloripirifos, temefos, permetrina y deltametrina. Ambas especies mostraron altos niveles de enzimas como citocomo P450 y glutatión S-tranferasa, mientras que los nive­les de esterasas variaron por especie y sitio muestreado. Se detectó acetilcolinesterasa insensible a insecticidas en ambas especies. Conclusión. En un hábitat urbano de Tapachula, Chiapas, México donde se aplica control con insecticidas Ae. aegypti y Ae. albopictus sólo son susceptibles al propoxur.
Sexual orientation disparities in food insecurity and food assistance resource use in U.S. adult women: National Health and Nutrition Examination Survey, 2005-2014
Authors: Patterson Joanne G , Russomanno Jennifer , Tree Jennifer M Jabson
Published: June 2020

Background. Nearly 40 million American adults report past year food insecurity. This is concerning, as food insecurity is associated with chronic disease morbidity and premature mortality. Women disproportionately experience food insecurity, and sexual minority women (i.e., lesbian, bisexual, and heterosexual women reporting same-sex behavior; SMW) may be at greater risk for experiencing food insecurity disparities. The purpose of this study was to investigate patterns and prevalence of food insecurity and food assistance use in sexual minority and exclusively heterosexual women using population-level health surveillance data. Methods. Using pooled 2004-2014 National Health and Nutrition Examination Survey data (N = 7379), we estimated weighted point prevalence of past 12-month food insecurity, severe food insecurity, Supplemental Nutrition Assistance Program (SNAP) use, and emergency food assistance use. We then used Poisson regression with robust variance to estimate prevalence ratios comparing SMW to exclusively heterosexual women on all outcomes. Women were classified by sexual identity and lifetime same-sex behavior as lesbian (n =88), bisexual (n = 251), heterosexual and reporting same-sex behavior (heterosexual WSW; n = 366), or exclusively heterosexual women (referent; n = 6674). Results. Between 20.6-25.5% of lesbian, bisexual, and heterosexual WSW reported past 12-month food insecurity (versus 13.1% of exclusively heterosexual women). All SMW reported greater prevalence of past 12-month food insecurity and severe food insecurity than exclusively heterosexual women: prevalence ratios (PR) ranged from 1.34 (95% confidence interval [CI], 1.05-1.70) to 1.84 (95% CI, 1.13-3.01). No differences were found in SNAP participation by sexual orientation, but more lesbians and heterosexual WSW reported using emergency food assistance in the past 12-months (PR = 1.89; 95% CI, 1.29-2.79 and PR = 1.43; 95% CI, 1.03-2.00 respectively). Conclusions. All SMW reported higher prevalence of food insecurity than exclusively heterosexual women. Lesbians and heterosexual WSW were also more likely to rely on emergency food assistance. This is problematic as SNAP use may reduce food insecurity over time, but emergency food resources (e.g., food pantries) do not. More evidence is needed to understand the multilevel factors driving food insecurity in this population to develop policy and community-based efforts to increase SNAP participation and decrease food insecurity.
Factors influencing happiness in the elderly based on the Anderson model
Authors: Zhang Xueying , Huang Shuang , Jing Lijia , Liu Zongzhuang , Wang Xin , Li Li
Published: June 2020

Background: The happiness of elderly people is an important indicator of successful aging. Research shows that happiness among the elderly is not only affected by physical conditions, social relations and other factors, but is also used as a measure of other aspects of happiness. This study examined the relationship between happiness and social relationships, contextual characteristics, and the medical outcomes of the elderly in China.Methods: Using multistage sampling method, a cross-sectional survey was conducted in Heilongjiang Province, China. 1003 elderly people participated in this study. We used the Life Satisfaction Scale, social isolation scale and EQ-5D to measure the happiness, social participation and health status of the elderly. In this study, structural equation modeling and descriptive analysis were used for analysis.Results: The main factors for happiness in the elderly were social relationships (γ = 0.507, P<0.001), contextual characteristics (γ= 0.256, P<0.001), and medical outcomes (γ= 0.232, P=0.015). Among these, the most important factor in the dimension of social relationships was social isolation (γ = -0.757 P<0.001), the most important factor in the dimension of contextual characteristics was monthly income (γ = 0.955 P<0.001), and the most important factor in the dimension of medical outcomes was physical health (γ = 0.600 P<0.001). There were also some relationships among three other dimensions.Conclusions：For the elderly, we must pay attention to social relations and reduce the sense of social isolation. At the same time, we should provide more medical resources for the elderly and maintain their health.
Detection of a novel gene mutation, ERBB2 exon 20 insertion, in bronchial adenoma using next-generation sequencing and a review of the literature
Authors: Wu Qian , Li Lin , Zheng Ke , Tang Yuan , Jiang Lili
Published: June 2020

Objectives: Ciliated muconodular papillary tumor (CMPT) is a rare peripheral lung tumor and is a subtype of bronchial adenoma (BA). Although recent studies have suggested that BA is a neoplastic disease, the complete histogenesis of BA is not fully understood and molecular data are limited. Methods: We examined the clinicopathological features of four patients with BA and performed immunohistochemical analysis and next-generation sequencing to characterize the molecular features of BA. A review of the previous literature was also undertaken to comprehensively conclude the molecular characteristics of this disease. Results: From previous studies and the present study, 99 BA /CMPT cases have been reported to date, with most of the patients from East Asia (77/99, 77.8%). The median age was 64 years old and the ages ranged from 19 to 84 years. The proportion of males and females was close, being approximately 1:1.3. From the computed tomography images, the BA /CMPT tumor usually presented as a peripheral solid mass, part-solid nodules, or ground-glass opaque with an irregular border and occasional central cavities. ERBB2, EGFR, BRAF, and AKT1 mutations were found on the computed tomography images of the BAs. To the best of our knowledge, this is the first study to report about ERBB2 exon 20 insertion in BA. Conclusion: BA /CMPT is a rare pulmonary disease that mainly affects elderly Asian patients. Many abnormal molecular changes were found, which confirmed the neoplastic nature of BA /CMPT. However, it also added to the debate regarding the biological behavior of BA /CMPT.
1 Selenium Supply Alters Subcellular Distribution and Chemical Forms of Cadmium and Expression of Transporter Genes Involved in Cadmium Uptake and Translocation in Winter Wheat (Triticum Aestivum)
Authors: Zhu Jiaojiao , Zhao Peng , Nie Zhaojun , Shi Huazhong , Li Chang , Wang Yi , Qin Shiyu , Qin Xiaoming , Liu Hongen
Published: June 2020

Background

Cadmium (Cd) accumulation in crops will affect the yield and quality of crops, and also harm human health. The application of selenium (Se) can reduce the absorption and transport of Cd in winter wheat.
Results

The result showed that increasing Se supply significantly decreased Cd concentration and accumulation in shoots and roots of winter wheat, and the root to shoot translocation of Cd. The Se supply increased the root length, surface area and root volume, but decreased the root average diameter. Increasing Se supply significantly decreased Cd concentration in cell wall, soluble fraction and cell organelle in roots and shoots. An increase of Se supply inhibited Cd distribution in the organelle of shoot and root, but enhanced Cd distribution in the soluble fraction of shoot and the cell wall of root. The Se supply also decreased the proportion of active Cd (ethanol-extractable (FE) Cd and deionized water-extractable (FW) Cd) in roots. In addition, the expression of TaNramp5-a, TaNramp5-b, TaHMA3-a, TaHMA3-b and TaHMA2 were significantly increased with the increase of Cd concentration in roots, and the expression of TaNramp5-a, TaNramp5-b and TaHMA2 in roots were down-regulated by increasing Se supply, regardless of Se supply or Cd stress, respectively. The expression of TaHMA3-b in root was significantly down-regulated by Se10 treatment at both Cd5 and Cd25 but up-regulated by Se5 treatment at Cd25. The expression of TaNramp5-a, TaNramp5-b, TaHMA3-a, TaHMA3-b and TaHMA2 in shoot were down-regulated by increasing Se supply at Cd5, and Se5 treatment up-regulated the expression of those genes in shoot at Cd25.
Conclusions

The results confirm that Se application limit Cd accumulation in wheat via regulating subcellular distribution and the chemical forms of Cd in tissues of winter wheat, as well as the expression of TaNramp5-a, TaNramp5-b and TaHMA2 in root.
The Binding Behaviors between Cyclopentanocucurbit[6]uril and Three Amino Acids in the Solid and the Solution Phases
Authors: Cheng Si Yuan , Zhao Wei Wei , Yang Xi Nan , Wei Lian Tong , Tao Zhu , Ma Peihua
Published: June 2020

Binding behaviors between CyP 6 Q[6] and three have been investigated by means of X-ray crystallography, 1 H NMR spectroscopy,amino acids and isothermal titration calorimetry (ITC). The results showed that CyP 6 Q[6] forms a 1:2 inclusion complex with glycine, but 1:1 complexes with both leucine and lysine. Whereas the carboxyl group of glycine can enter the interior of the cavity of CyP6Q[6], only the alkyl chains of leucine and lysine can enter this cavity. Interestingly, leucine can adopt two different self-assembly modes upon its interaction with cucurbituril, depending on the external conditions, whereas glycine and lysine do not exhibit such behavior.
Interleukin-6 and vitamin D serum levels in patients with obstructive sleep apnea syndrome before and after long-term continuous positive airway pressure treatment
Authors: Kotsiou Ourania S , Siachpazidou Dimitra I. , Pastaka Chaido , Gogou Eudoxia , Kechagia Maria , Varsamas Charalampos , Hatzoglou Chrissi , Gourgoulianis Konstantinos I.
Published: June 2020

Background: Hypoxia induces the production of adipocyte-derived mediators such as IL-6 in obstructive sleep apnea syndrome (OSAS). Low serum 25-hydroxyvitamin D (25(OH)D) levels have been linked to OSAS susceptibility. No data exist to assess whether there has been a correlation between vitamin D and IL-6 serum levels. The effect of CPAP therapy on IL-6 or 25(OH)D levels has yet to be investigated sufficiently in OSAS. We aimed at determining the serum levels of 25(OH)D and IL-6 in OSAS patients compared to non-apneic controls, investigating a possible correlation between 25(OH)D and IL-6 levels and evaluating the changes in IL-6 and 25(OH)D concentrations after twelve months of CPAP therapy in OSAS patients.Methods: 15 OSAS patients diagnosed by polysomnography and 15 non-apneic controls were included in the study. Serum IL-6 and 25(OH)D levels were measured before and after twelve-month CPAP therapy in the whole population and OSAS group, respectively.Results: IL-6 levels were significantly elevated in the OSAS group than the controls. IL-6 levels were positively correlated with OSAS severity, nocturnal hypoxemia, and body mass index (BMI). No difference was detected in 25(OH)D serum levels between groups. We found no correlation between IL-6 and 25(OH)D serum levels in two groups. No effect on IL-6 or 25(OH)D levels was detect after one year of effective CPAP therapy in OSAS patients.Conclusions: IL-6 levels were correlated with OSAS severity, hypoxemia, and BMI. No correlation between 25(OH)D and IL-6 levels and no effect of long-term CPAP on biomarkers were found in OSAS patients.
LINC00899 Promotes Osteogenic Differentiation and Alleviates Osteoporosis via Targeting miR-374a to Regulate RUNX2
Authors: Gao Xiaoya , Xue Yun , Yang Kechun
Published: June 2020

Objective: This study aims to illustrate the underlying molecular mechanisms of long noncoding RNAs (LncRNAs) LINC00899 in osteoporosis.Methods: Real Time-quantitative Polymerase Chain Reaction (RT-qPCR) used to examine the levels of LINC00899, miR-374a and RUNX2 in clinical tissues or human bone mesenchymal stem cells (hBMSCs). The interaction between miR-374a and LINC00899 or RUNX2 was predicted by starBase and verified by luciferase reporter assay and RNA binding protein immunoprecipitation (RIP) assay. Results: The expression of LINC00899 was lowly expressed in osteoporotic patients’ bone tissues and knockdown of LINC00899 decreased the expression of osteogenesis-related genes. Moreover, LINC00899 was confirmed to inhibit miR-374a expression by direct interaction. the expression levels of LINC00899 were gradually increased, but miR-374a expression was decreased with the prolongation of osteogenic induction. Finally, we demonstrated that RUNX2 was a target of miR-374a, and the silencing of miR-374a partially abolished the inhibitory effect of LINC00899 knockdown on the expression of RUNX2, OPN and OCN.Conclusions: We demonstrated that LINC00899 facilitated osteogenic differentiation of hBMSCs and prevent osteoporosis by sponging miR-374a and enhancing RUNX2 expression, which might provide a useful therapeutic strategy for osteoporosis patients.