bluuebunny/crossref_metadata_2025 huggingface dataset:
A Contestation of Indonesian and Thailand's National Interest in Cooperation on Narcotics Management
Authors: Reformanda Chrisindo , Djuarsa Samuel
Published: October 2023

This article discusses the pessimistic attitude towards international cooperation between Indonesia and Thailand. The bilateral cooperation in the drug field that took place between the two countries on December 8, 2016 was in fact only a tool used for the interests of each country and ended the competition of interests between both countries. So the collaboration planned for five years must end in the third year. The purpose of this article is to look at the changes in attitudes between the two countries and the dynamics of contesting the national interests of Indonesia and Thailand in cooperation in narcotics. The collaboration between the two countries is studied from a realistic perspective by paying particular attention to the concept of national interest to understand the motivation of the two nations to cooperate, as well as revealing the reasons for the non-implementation of cooperation in 2020 – 2021. The data presented in this study is in the form of primary data through interviews with a number of sources and secondary data obtained through library studies. In the findings of the research, the failure to cooperate between the two countries was found notwithstanding the heterogeneity or differences in behaviour and actions caused by their respective internal factors, both political and economic needs and security issues. This research shows that the national interests of the country in fact drive the interaction between Indonesia and Thailand. The author finds that the change in attitude between Indonesia and Thailand is the result of the regulatory change that Thailand has made in dealing with narcotic drugs like marijuana. These differences of opinion are considered significant and affect many aspects between the respective countries. So cooperation is no longer possible.

Keywords: National interest; Transnational crime; Non-traditional security; International cooperation; Indonesia; Thailand.
Firm specifics, Trade liberalization, and export intensity with the moderating role of location advantages- Empirical evidence from Vietnam
Authors: Vo Quy T. , Ho Tin H. , Bui Hien T.T. , Le Khoa N.A.
Published: October 2023

Vietnam has experienced an impressive period of economic growth recently. Since the foreign trade relation of Vietnam expanded, the export sector has been outperformed with a double-digit growth rate, especially Ho Chi Minh City (HCMC). To study the impact of firm specifices, trade liberalization on export intensity (EI) of Vietnamese exporters with moderating effect of location advantages on the relationship between firm specifics and EI, data was collected from 61 exporters listing in Vietnam stock markets from 2010 to 2020. The regression test was carried out by applying GMM model and showed that firm productivity has a negative impact on EI while cost to income ratio has a psotive impact on EI at the significance level of 5%. Trade liberalization has a positive impact on EI significantly at 5%. The findings confirmed the moderating role of firm location in the relationship between firm specifics and EI. The findings support RBV theory, and trade liberalization policy.

Keywords: Trade liberalization, location advantages, export intensity, Ho Chi Minh City, Vietnam.
Growth and instability of rice production: a district level analysis in West Bengal, India
Authors: Jambhulkar Nitiprasad Namdeorao , Mondal Biswajit , Bisen Jaiprakash , Pradhan Asit Kumar
Published: October 2023

West Bengal is the largest rice-producing state in the country. It contributes significantly to the national production pool and is one of the important rice consuming state. It is essential to study the growth pattern of rice production in the state. The district wise information of growth rate and instability is not available. Also the association of growth rate and instability has not been studied. Hence the present study was conducted to compute the district wise growth rate and instability in the area, production and yield of rice in West Bengal state and to examine the association between growth rate and instability. The district-wise data on rice was sourced from the Directorate of Economics and Statistics, Ministry of Agriculture and Farmers Welfare, Government of India for the period 1983-84 to 2019-20. The data has been divided into five periods for analysis. Compound annual growth rate and Cuddy-Della Valle Instability index have been computed for the five periods. The instability was divided into five classes. These classes are very low instability, low instability, medium instability, high instability and very high instability.The highest growth rate for area and production was recorded in Nadia district during period I (1983-34 to 1989-90) while the highest growth rate for yield was recorded in South Dinajpur district during period IV (2010-11 to 2019-20). The growth rate for production and yield was positive for all the districts during periods IV (2010-11 to 2019-20) and V (1983-84 to 2019-20). Only one district recorded a negative growth rate for production during period I (1983-84 to 1989-90) and for yield during the period I (1983-34 to 1989-90), III (2000-01 to 2009-10) and IV (2010-11 to 2019-20). The instability varied from 0.63 to 26.57 percent in area, 1.49 to 19.46 percent in production and 0.70 to 45.95 per cent in yield across the districts over five periods.None of the districts recorded very high instability for area, production and yield; high instability for area and production; and medium instability for yield.Most of the districts showed very low instability for area and yield during periods I (1983-34 to 1989-90), II (1990-91 to 1999-2000), III (2000-01 to 2009-10) and IV (2010-11 to 2019-20); and low instability during period V (1983-84 to 2019-20). For production, the highest number of districts recorded low instability during periods I (1983-34 to 1989-90), III (2000-01 to 2009-10), and V (1983-84 to 2019-20) and very low instability during period II (1990-91 to 1999-2000) and IV (2010-11 to 2019-20). The growth in area is moving around zero, which indicates little scope in area expansion. The increase in rice demand can achieved through introduction of new high yielding varieties and application of site specific crop management techniques. For this a comprehensive database may be developed at disaggregated level to implement the policy at district level in West Bengal.
Extreme weather events and its impacts on rice production in coastal Odisha region of India
Authors: Vijayakumar S , Nayak AK , Manikandan N , Pattanaik Suchismita , Tripathi Rahul , Swain CK
Published: October 2023

The study examines extreme daily precipitation and temperature trends in coastal Odisha, India by calculating 18 weather indices (8 temperature indices and 10 rainfall indices) using the RClimDex software package for the period 1980-2010. Statistical significance of the indices was determined through trend analysis using linear regression and non-parametric Mann-Kendall test. Results indicated, a strong and significant trend in temperature indices while the weak and non-significant trend in precipitation indices. The positive trend in Tmax mean, Tmin mean, TN90p (warm nights), TX90p (warm days), diurnal temperature range, warm spell duration indicator, consecutive dry days indicates increasing the frequency of warming events in coastal Odisha. Similarly, positive trend in highest maximum 1-day precipitation, highest maximum 2-consecutive day precipitation, highest maximum 3 consecutive day precipitation, highest maximum 5-consecutive day precipitation, number of heavy precipitation days (64.5mm), number of very heavy precipitation days (124.5mm) and negative trend in the number of rainy days (R2.5mm), consecutive wet days indicate changes toward the more intense and poor distribution of precipitation in coastal Odisha. Extreme precipitation and temperature events negatively impacted rice yield, with a sharp decline observed in all coastal districts. The study highlights the need for new technology/management practices to minimize these impacts.
Características clinicopatológicas e índice de masa corporal en mujeres Uruguayas portadoras de cáncer de mama asistidas en el Hospital de Clínicas
Authors: Camejo Natalia , Amarillo Dahiana , Ceriani Florencia , De León Manfrú Lidia , De Olea Florencia , Diaz Mauricio , Donato Franco , Suarez Alexandra , Tamborindeguy Rocio , Castillo Cecilia , Krygier Gabriel
Published: October 2023

Objetivo. Describir las características clinicopatológicas del cáncer de mama (CM) en mujeres con sobrepeso/obesidad y su manejo en la práctica clínica, en pacientes uruguayas asistidas en Servicio de Oncología del Hospital de Clínicas. Material y métodos. Estudio observacional, descriptivo, retrospectivo de corte transversal, que incluyó a pacientes con diagnóstico de CM del centro ya mencionado, desde enero de 2020 a mayo de 2022. Se evaluaron las variables demográficas, índice de masa corporal, subtipo histológico, receptores hormonales, HER 2neu y tratamiento recibido. Pruebas estadísticas: media y desvío estándar. Analíticas: Chi cuadrado para variables cualitativas y test de Student para variables cuantitativas. Resultados. Se incluyeron 141 pacientes, 56% presentaba sobrepeso/obesidad. La mediana de edad al momento del diagnóstico fue similar para ambos grupos: 58 vs. 58.8 años (p =0.762). Entre las pacientes con sobrepeso/obesidad fueron más frecuente: el carcinoma ductal (p = 0.005); los tumores luminales, aunque sin significancia estadística, y la mastectomía (p =0.012). Mientras que entre las pacientes con normopeso fueron más frecuente: el carcinoma lobulillar (p = 0.043), los tumores triple negativos si bien estos valores no fueron estadísticamente significativos y la cirugía conservadra (CC) (p =0.012).La proporción de pacientes que presentaron recaída fue similar en ambos grupos (p =0.48). Conclusiones. En nuestro estudio el sobrepeso y la obesidad no se relacionaron con la mayoría de las características del CM, pero sí en el tipo histológico y tipo de tratamiento quirúrgico. No se observaron diferencias significativas en la tasa de recaída entre los dos grupos de pacientes.
Hermilio Valdizán Medrano: ilustre huanuqueño XCIV años de historia
Authors: Machiavello Edwin A.
Published: October 2023

El legado histórico de Hermilio Valdizán en la medicina peruana es notable. Su enfoque humanista es reconocido internacionalmente, así como su contribución a la psiquiatría moderna. A través de sus numerosas obras, Valdizán exploró temas como la historia de la medicina en el Perú, el tratamiento de los enfermos mentales durante la época colonial, así como la evolución de la ciudad de Lima a lo largo del tiempo. Su prematura muerte dejó un gran vacío en el campo de la medicina, pero su legado perdura como una influencia significativa en la práctica e investigación de la psiquiatría en el Perú.
Application of the sub-classification AGC NOS and AGC FN in Pap Smears AGC: utility in clinical practice
Authors: Antognoli Davide , Zampatti Clementina , Cattaneo Gabriella , Armiraglio Simona , Crivelli Filippo
Published: October 2023

With the use of the pap smear in screening programs there has been a decrease in cervical cancer but the papsmear is also a tool for early diagnosis of endocervical adenocarcinoma. Endocervical adenocarcinoma is adelicate disease because, even though it is a rare disease, it is becoming more and more widespread, affectingyoung women of childbearing age. Furthermore, it is asymptomatic, hardly visible colposcopically and is alsoa dangerous disease whose risk does not diminish after diagnosis of AGC but remains high over time.The study aims to evaluate the usefulness of the subcategory of the AGC in AGC NOS and AGC FN to assesswhether the use can give advantages in clinical practice93248 Pap Smears were considered in this study, of which only 50 were suitable for the study (diagnosis ofAGC and histological examination on the endocervix), these were reclassified according to the indications ofBethesda in AGC NOS and AGC FNIn the reclassified Pap Smears as AGC NOS we obtained, on the histological examination, 79% of lesions oflow clinical-evolutionary impact and only the 21% of lesions with a high clinical-evolutionary impact. on theother hand, in the reclassified Pap Smears as AGC FN we obtained 23% of lesions of low clinical-evolutionaryimpact and the 77% of lesions with a high clinical-evolutionary impact. In addition, in patients over 50 withthe diagnosis of AGC FN, extracervical diseases prevailThe sub-classification in AGC NOS and AGC FN has proved useful to guide the clinician in carrying out moredetailed examinations in women diagnosed with AGC FN and moreover in a patient over 50 years the diagnosisof AGC FN must orientate the clinician to an extension of the investigations also, and above all, at the levelof the remaining parts of the genital apparatus (in particular the endometrium) or of the neighboring organs(bladder, rectum).
The role of home radiology in a post-earthquake mountain environment, the possible example of Amatrice
Authors: Sanesi Emanuele , Casalino Paolo , Ferrazza Andrea , Fossati Pierpaolo , Del Signore Enrico , Corradetti Alessandro , Casciani Maria Grazia
Published: October 2023

Following the earthquake of August 24, 2016 that hit Central Italy, the only hospital in the Amatriciana valley represented by F. Grifoni, was closed due to its unusability. Subsequently, the ASL of Rieti, in support with the Lazio Regionand the National Civil Protection, in 2017 to make up for this deficiency, created a PASS (socio-health assistancepoint) with also a diagnostic image for the needs. of the First Aid h12, not including outpatient radiological examinations to the many inhabitants who have decided, with stubbornness and tenacity, not to abandon these magnificentvillages. Precisely for the sense of self-denial and gratitude to these lands, which also welcomed some of us (Enrico,Emanuele, Alessandro) as TSRM professionals within the Amatrician hospital, we decided together with other colleagues to collaborate and create an innovative project of health revival. Using a SWOT matrix and a cost / effectivenessanalysis, we have designed a home radiology service capable of delivering diagnostic tests to the entire communitywhich has a mountain area of 174 km2, 69 hamlets and a high old age index among the population.
SOCIALLY RESPONSIBLE PRACTICES IMPLEMENTATION IN THE ENTERPRISE VALUE MANAGEMENT TAKING STAKEHOLDERS' INTERESTS
Authors: Krasnokutska Nataliia , Gao Liang
Published: October 2023

Building an enterprise value management system requires analyzing and evaluating results of this system, as well as the programs and projects carried out within the framework of Sustainable Development Goals (SDGs). Current assessment tools are mostly based on comparing actual and target values of each sustainable development goal. In practice, to improve the existing developments regarding the evaluation results of SDGs implementation, an author substantiates legal and methodological approach to assessing the implementation status within SDGs implementation, involving diagnostics based on the value creation stages, including the criteria of efficiency, compliance to the interests of stakeholders and their benefits.
INSILICO ANALYSIS OF CorA SUPERFAMILY MAGNESIUM TRANSPORTERS OF FUNGI AND IDENTIFICATION OF MAGNESIUM TRANSPORTER STMg WITH GQN MOTIF FROM NEUROSPORA CRASSA
Authors: Radarapu Sireesha , Gorityala Neelima , Kumar Banala Uday , Rao Sagurthi Someswar , Korripally Premsagar
Published: October 2023

The Neurospora crassa genome encodes four putative CorA transporters Tmg-1, Tmg-2, Tmg-3, and
Tmg-4. The GQN motif is found on the Tmg-4 transporter encoded by the NCU07816.5 (tmg-4) gene in
contrast to the conserved GMN motif which is essential for the structure and function of CorA magnesium transporters. We were
intrigued to see the wide distribution of variant motif GQN in place of GMN across the fungi. Using various bioinformatics tools,
we catalogued around 300 protein sequences with tentative CorA superfamily features from 100 fungal species belonging to all
phyla. Surprisingly, the proteins with the GQN motif and CorA domain are mostly present in the Sordariomycetes class of fungi
and are named STMg. In STMg proteins the GQN motif is anked by phenylalanine residues, and the glycine of the motif is
present in the rst transmembrane helices, and the remaining two residues glutamine and aspargine are present in the loop.
Phylogenetic analysis of STMg proteins and other CorA proteins resulted in four clades namely, ALR, MNR2, MRS2, and STMg.
The predicted model Tmg-4 of N.crassa was subjected to structural comparison with its closest homolog, TmCorA of
Thermotoga maritime. The alignment of Tmg-4 and TmCorA structures resulted in good superimposition which is indicated by
a RMSD value of 0.96Å. Insilico analysis of four clades and structural superposition of the crystal structure of CorA (GMN motif)
with a homology model of Tmg-4 (GQN motif) conrms GQN as a novel motif and suggests that it may be involved in
magnesium transport in Neurospora crassa.
RECURRENT RAPUNZEL SYNDROME IN A 23-YEAR-OLD FEMALE WITH A HISTORY OF INGESTED HAIR SINCE CHILDHOOD : A CASE REPORT
Authors: Vidit Vidit , Verma Sandeep , Yadav Dushyant , kant Shashi , Ranga Hansraj , K Arora Bhavinder
Published: October 2023

Rapunzel syndrome is characterized by the injection of hair leading to the formation of trichobezoar
extending from the stomach into the small intestine, which is a rare condition observed in the young
females with psychiatric illness. We present a case of a 23-year-old female with a long-standing history of hair ingestion since
childhood who previously underwent surgical intervention for trichobezoar 11 years ago. The patient was admitted for
emergency laparotomy due to worsening of generalized abdominal pain,nausea and multiple episodes of vomiting.Imaging
studies revealed an intragastric homogeneous mass extending into the small intestine causing intestinal obstruction. The
postoperative period was uneventful along with psychological support and counseling to address the underlying trichophagia
and psychiatric aspects contributing to the recurrent condition. This case report highlights the need for early recognition,
appropriate surgical intervention and multidisciplinary management including psychiatric evaluation to address the
psychological factors associated with recurrent Rapunzel syndrome.
ECONOMIA MONETÁRIA DE GEORG SIMMEL E O DINHEIRO EM MARX
Authors: E Silva William Gledson , Ferreira Francisco Danilo Da Silva
Published: October 2023

Este artigo teve o objetivo de analisar a possibilidade de convergência entre o modelo de economia monetária de Georg Simmel e o dinheiro na teoria de Karl Marx, partindo de uma formulação exclusivamente teórica. Metodologicamente, usou-se uma revisão de literatura à construção de um modelo explicativo. Os resultados demonstraram que houve uma possibilidade não desprezível entre o modelo de Simmel na perspectiva do espírito das pequenas cidades diante do autoconsumo envolvido no circuito Mercadoria (M) Dinheiro (D) Mercadoria de Marx. Adicionalmente, o Espírito das grandes cidades frente ao circuito Dinheiro Mercadoria e mais Dinheiro (D), respectivamente em Simmel e Marx complementaram esta análise, pois aspectos de teorias tão divergentes permitiram construir, provavelmente, um modelo explicativo.
Jasmonic acid impact on botanical and morpho-physiological characteristics of wheat (Triticum aestivum L.) infected by Aphid
Authors: Sumera Sumera , Nawaz Azqa , Ikram Muhammad , Karim Abdul , Ullah Saeed , Atta Shahab , Nazar Naik , Ullah Sami , Yousuf Naheed
Published: October 2023

Wheat (Triticum aestivum L.) is the most essential cereal crop among all other crops of Pakistan and belongs to the family poaceae. The experiment was performed to evaluate the response of exogenously applied jasmonic acid on wheat (Triticum aestivum L.) growth parameter against aphid attack. Two wheat varieties i.e., Fareed-2006 and Paktoon-2016 are cultivated in pots and different concentrations of Jasmonic acid (100 µM and 1 mM) were applied. Concluded results showed that aphid infested plants decreased root and shoot length, plant height, total soluble protein and chlorophyll contents but increased the POD and SOD contents, MDA contents, catalase, H2O2 concentrations and phenolics of wheat (Triticum aestivum) which was further improved through jasmonic acid application. Jasmonic acid treated plants showed better results than control and aphid infested plants. Jasmonic acid spray helped plants to recovery from aphid stress by increasing antioxidant enzyme synthesis, POD (Peroxidase), SOD (Superoxide dismutase) and CAT (Catalase). The results showed that JA sprayed plants have a reduced aphid population than controls plants. When compared to jasmonic acid (100 µM), the greater concentration of jasmonic acid (1mM) showed more effective. Use of jasmonic acid against devastating diseases seems to hold a more promising future in the pest management and agriculture sector.
The Influence of Electronic Banking Transactions on Fee Base Income in Conventional Banking Listed on the Indonesia Stock Exchange for the 2018-2021 Period
Authors: Anita Gina , Christine Debbie
Published: October 2023

The background of this research is that there is still a research gap between the value of e-banking transactions and the value of fee-based income at several conventional banks listed on the Indonesia Stock Exchange. In addition, this research aims to find out how electronic banking transactions affect fee base income. The factors tested in this study are electronic banking transactions as the independent variable, while fee-based income is the dependent variable. The research method used is descriptive and verification method. The population in this study are conventional banks listed on the Indonesia Stock Exchange for the 2018-2021 period, totaling 41 banks. The sampling technique used is non-probability sampling with purposive sampling method, so that the total sample is 11 companies. The data analysis used is panel data regression analysis using Eviews. The results of the study show that electronic banking transactions and fee-based income in conventional banks listed on the Indonesia Stock Exchange for the 2018-2021 period tend to increase every year. In addition, the results of hypothesis testing show that electronic banking transactions have an effect on fee base income. The magnitude of the effect of electronic banking transactions on fee base income is 75.4%.
Esclerose Múltipla: Avanços no Diagnóstico e Tratamento: Uma análise das técnicas de diagnóstico, como a ressonância magnética, e as terapias imunomoduladoras utilizadas no tratamento da esclerose múltipla.
Authors: Diniz Renata Silva , Marques Mariana Queiroz Cunha , Chaves Sofia Amaral , Froes Giovanna Pacheco de Magalhães , Chaves Beatriz Amaral
Published: October 2023

A esclerose múltipla (EM) é uma doença neuroimunológica crônica que afeta o sistema nervoso central e representa um desafio significativo para os pacientes e profissionais de saúde. Este artigo de revisão analisa os avanços no diagnóstico e tratamento da EM, destacando sua importância para a prática clínica. No contexto do diagnóstico, a ressonância magnética (RM) emergiu como uma ferramenta crucial, permitindo a detecção precoce de lesões no sistema nervoso central. Avanços na RM, incluindo técnicas como a espectroscopia por ressonância magnética e ressonância magnética de difusão, têm melhorado a precisão diagnóstica. No que diz respeito ao tratamento, terapias imunomoduladoras, como interferons beta e agentes modificadores da doença (DMDs), têm se mostrado eficazes na redução das recaídas e no controle dos sintomas. Além disso, a terapia personalizada está emergindo como uma tendência promissora, reconhecendo a variabilidade de resposta entre os pacientes. A progressão da incapacidade é uma preocupação central na gestão da EM, e terapias como o ocrelizumabe têm demonstrado desaceleração significativa nesse processo, especialmente em pacientes com EM primária progressiva. A busca por biomarcadores, como o neurofilamento leve (NfL) e quimiocinas, oferece a possibilidade de prever a progressão da EM e ajustar o tratamento de forma personalizada. Em resumo, os avanços no diagnóstico e tratamento da EM têm impactado positivamente a qualidade de vida dos pacientes. A medicina de precisão está no horizonte, prometendo terapias mais eficazes e personalizadas. Profissionais de saúde devem estar atualizados com as evidências mais recentes para proporcionar o melhor cuidado aos pacientes com EM.
Avanços Terapêuticos de Última Geração para Cânceres Hematológicos: Leucemia, Linfoma e Mieloma
Authors: Severino Victor Vilela Carvalho , Reis Gustavo Novelino , Silva Ana Paula Oliveira , Passos Arthur Mendes Porto , Mendonça Ariany Parreira de
Published: October 2023

Este artigo de revisão destaca os avanços terapêuticos de última geração em cânceres hematológicos, como leucemia, linfoma e mieloma, que estão revolucionando o cenário do tratamento dessas doenças. Terapias-alvo, imunoterapias e a terapia CAR-T emergiram como pilares fundamentais no combate ao câncer hematológico, oferecendo resultados notáveis, como respostas profundas e duradouras. A personalização do tratamento, adaptada às características individuais do paciente e da doença, tem se mostrado essencial nesse contexto, embora persistam desafios significativos, como a resistência terapêutica e a acessibilidade global. No entanto, o futuro da oncologia hematológica é promissor, com a pesquisa contínua direcionada para aprimorar a qualidade de vida e as perspectivas de sobrevivência dos pacientes, proporcionando esperança e avanços contínuos no campo da hematologia oncológica. Essas inovações terapêuticas representam um marco na luta contra os cânceres hematológicos, com resultados que antes eram inimagináveis. As terapias-alvo direcionadas a mutações específicas, a imunoterapia que reforça a capacidade do sistema imunológico do paciente e a terapia CAR-T que utiliza células imunológicas modificadas para atacar as células cancerígenas estão demonstrando eficácia notável, proporcionando esperança para pacientes e médicos. No entanto, os desafios permanecem, com a necessidade de lidar com a resistência terapêutica que pode surgir ao longo do tempo e a garantia de que essas terapias avançadas sejam acessíveis globalmente. À medida que a pesquisa continua avançando, o horizonte da oncologia hematológica promete melhorias contínuas na qualidade de vida dos pacientes e em suas perspectivas de sobrevivência, estabelecendo um cenário onde o câncer hematológico pode ser tratado com eficácia e esperança renovada.
Changes in the cytokine status in women with exacerbation of bronchial asthma due to reactivation of cytomegalovirus infection in the second trimester of pregnancy
Authors: Andrievskaya I. A. , Nakhamchen L. G. , Gorikov I. N. , Ishutina N. A. , Odireev A. N. , Prokopenko A. V.
Published: October 2023

Aim. To study changes in the cytokine status in women with exacerbation of bronchial asthma caused by reactivation of cytomegalovirus infection (CMVI) in the second trimester of gestation.

Materials and methods. The concentration of pro-inflammatory cytokines (TNFα, IL-1β, IFNγ, IL-2) in blood serum was assessed in 112 women in the second trimester of pregnancy, uncomplicated and complicated by exacerbation of asthma caused by reactivation of CMVI. The first group included 30 women seronegative for CMVI with uncomplicated pregnancy. The second group consisted of 30 patients with exacerbation of mild asthma associated with CMVI, initiating the formation of chronic compensated placental insufficiency. The third group consisted of 27 patients with exacerbation of moderate asthma induced by CMVI reactivation leading to the development of chronic compensated placental insufficiency. The fourth group included 25 women with exacerbation of moderate asthma due to the acute phase of CMVI, which induces the development of chronic subcompensated placental insufficiency.

Results. It was found that in the blood serum of women of the first group, the concentration of TNFα was (Me) 21.5 (13.8–30.1) pg/mL, IL-1β – 18.2 (13.6–34.0) pg/mL, IFNγ – 137.4 (109.5‒174.2) pg/mL and IL-2 – 29.8 (21.0‒38.9) pg/mL. In patients of the second group, compared with the first one, there was an increase in the level of TNFα by 3.79 times (p=0.000001), IL-1β – by 4.8 times (p=0.000001), IFNγ – by 1.73 times (p=0.000001) and IL-2 by 2.91 times (p=0.000001). In the third group, unlike the second one, no significant differences were found between the concentrations of TNFα, IL-1β, IFNγ, and IL-2. In patients of the fourth group, in comparison with the third group, higher values of TNFα (1.35 times, p=0.00507), IL-1β (1.86 times, p=0.000001), IFNγ (1.31 times, p=0.000167), and IL-2 (1.5 times, p=0.0056) were registered.

Conclusion. During exacerbation of moderate asthma of cytomegalovirus etiology, leading to chronic subcompensated placental insufficiency, in comparison with exacerbation of moderate asthma caused by reactivation of CMVI, initiating the formation of chronic compensated placental insufficiency, activation of the systemic inflammatory response is most pronounced, leading to stimulation of the migration of monocytes, lymphocytes and neutrophils to the focus of inflammation at the level of small bronchi; also leading to disruption of intersystem relationships and to hemodynamic dysfunction of the placenta.
Automation control of the impregnation and swelling process for polymer materials
Authors:   Filippenko N.G.
Published: October 2023

An automated control system of the polymer the impregnation and swelling process, which makes it possible to significantly reduce the time for conducting control tests of polymeric materials, are developed and implemented based on the analysis of the state of the control systems of existing equipment designed to study the process of impregnation and swelling of polymers.

Keywords
automation, algorithm, polymers, elastomers, impregnation, swelling
Development of algorithms for optimizing business processes of interaction with consumers in a gas distribution organization
Authors:   Gagloeva I.E.
Published: October 2023

The results of a detailed analysis of the main information flows in a gas distribution company and the features of workflow automation when working with clients are presented. Algorithms for optimizing business processes based on the implementation of an IT-project have been developed. The proposed algorithms for interaction with clients and ways of organizing the company’s information space will improve the quality of customer service and the efficiency of organization management.

Keywords
data optimization, information flow, information technology, business process, algorithm, gas distribution organization, implementation efficiency, IT-project
Conocimientos sobre sexualidad sana y responsable en estudiantes de primer año de Medicina de la Universidad de Ciencias Médicas de Camagüey
Authors: Gómez Ferrer Dayana , Nobalbo Aguilera Yunexis Teresa , Mirón Folgoso Cynara , Alonso Benavente Marisbel
Published: October 2023

Se realizó una investigación participativa de carácter cuanticualitativoa estudiantes pertenecientes al Grupo I de primer año de la carrerade Medicina en la Universidad de Ciencias Médicas de Camagüey enel curso académico 2020-2021. Se aplicó una encuesta a los alumnoscon el objetivo de determinar el conocimiento que poseen sobre lasexualidad responsable. La muestra quedó constituida por 55 estudiantes.Predominaron las féminas y el grupo de edad entre los 17 y19 años, la mayoría de ellos tenía como estado civil la unión estable.54,5 % manifestó tener conocimiento sobre sexualidad. Además, 54,4% no tiene conocimientos plenos de lo que son las infecciones detransmisión sexual ni de los métodos anticonceptivos. Mientras que7,3 % de los encuestados no le dan importancia a tener conocimientosobre el tema. La investigación constituye una salida del proyecto deinvestigación “Formación sociohumanista en la educación médica superior”,que gestiona el Centro de Desarrollo de las Ciencias Sociales yHumanísticas en Salud, adscrito a la Universidad de Ciencias Médicasde Camagüey y se llevó a la práctica desde septiembre de 2020 afebrero del 2021.
A Proposed Normative Framework “Najaz Program” to Develop Performance Indicators in Secondary Schools in the Kingdom of Saudi Arabia, “longitudinal Study”
Authors: Alkhrizi Mohammed
Published: October 2023

The main goal of this study is to prepare and implement a proposed normative framework, represented by the “Najaz” program for developing performance indicators in secondary schools in Saudi Arabia, through tracking for a period of three years: (2020-2021-2022) in the field of learning outcomes, regularity, behavior, talent, professional development, values, volunteering and participation, excellence, e-learning, beneficiaries, school environment. The the descriptive method (longitudinal) was used, and the population consisted of (30) schools in Qunfudah educational Directorate, with a percentage of (30.60%) of the society. The follow-up results indicated that there were statistically significant differences at the level of (0.01) in the improvement of standards and performance indicators of the “Nagaz” program for secondary schools on the graded performance thresholds during the three years of the program, in favor of the most recent years of implementation. Where the total achievement threshold for the first year of the program (2020) came with a “low” grade, expressed in the color “orange”, while in the second year (2021) the achievement threshold reached the grade “medium” and expressed in the color “yellow”, while in the third year (2022) The achievement threshold has reached the “advanced” grade, which is indicated by the color “dark green”. Keywords: Najaz programme, colored recognition thresholds, digital dashboard, performance indicators, secondary schools in the Kingdom
Awareness of Cybersecurity and its Relationship to Digital Transformation among Supervisors of the Education Department in Jazan Region
Authors: Otayf Maryam
Published: October 2023

The study aimed to identify the degree of awareness of cybersecurity, and to reveal the reality of digital transformation and the relationship between them from the point of view of the supervisors of the Education Department in the Jazan region. The study followed the descriptive correlative approach, by stratified random sampling (257). a questionnaire was built , The study found that the degree of cybersecurity awareness is high with an arithmetic mean of (3.48), and also degree of awareness of cybersecurity concepts is high, (3,52), and awareness of cybersecurity risks and violations (3.45), and it was found that the total degree of transformation The digital dimension was high with an arithmetic average of (3.46) and the dimensions ranged from (3.60-3.23) in high degrees, except for the necessary funding, which appeared in a medium degree, and it was in order (technological infrastructure, legislation and administrative policies supporting digital transformation, technical skills, and the necessary funding It was also found that there is a statistically significant correlation at the level (0.01) between cybersecurity awareness and digital transformation. The value of the relationship is (0.83) Keywords: cyber security, digital transformation, education management in Jazan region.
Muchas hambres exigen muchas soluciones
Authors: de Felipe Isabel , Briz Julián
Published: October 2023

El trabajo plantea un horizonte amplio de las necesidades básicas del ser humano en diversos horizontes: alimentación, salud, cultura y justicia social, entre otros, analizando sus causas y posibles soluciones. Hay distintos grados de emergencia en la resolución de problemas, figurando en primer término el abastecimiento alimentario, en estrecha correlación con otras modalidades. Su complejidad exige la participación de profesionales diferentes, encuadrados en organismos nacionales e internacionales, así como en ONGD. Se recogen aspectos técnicos y prácticos haciendo hincapié en las causas originarias, lo que permite plantear soluciones desde su raíz. Hay una descripción de la situación actual y su evolución en las últimas décadas, evaluando la gravedad de acuerdo con fases preestablecidas por la experiencia. Todo ello nos lleva a diseñar soluciones en los distintos tipos de hambre. Se describen la experiencia adquirida, los errores cometidos y los recursos disponibles que permitan acabar con el hambre, drama pendiente de la Humanidad, para el que existen recursos, pero falta voluntad.
Starvation and international crime
Authors: Dannenbaum Tom
Published: October 2023

One of the most pernicious causes of the backsliding on global hunger is the human infliction of deprivation, whether in the form of belligerents’ decisions about how to wage war or governments’ decisions about how to exercise control over populations. Some of these decisions are criminal, but accountability is rare. Change requires building the confidence of prosecutors and investigators in the viability of the legal tools available, despite the relative graduality of the effects of deprivation as compared to other atrocity crimes, the challenges associated with establishing the cause of those effects in complex and multivariate conditions, and the fact that many of those subject to mass deprivation endure torturous suffering without dying. Given that context, the agents of international criminal accountability would do well to focus on the war crime of starvation of civilians as a method of warfare and the crime against humanity of “other inhumane acts.” This article explains why those crimes are most expressively and evidentiarily apt and charts the contours of the relevant law.
PEMANFAATAN EDUGAME ISI PIRINGKU SEBAGAI MEDIA PENINGKATAN PENGETAHUAN IBU BALITA
Authors: Purwaningsih Puji , Chairijah Zumrotul , Sifai Izzatul Alifah
Published: October 2023

Introduction & Aim: Nutritional problems still need to be solved in various parts of Indonesia. Cases of nutrition can be excess nutrition or malnutrition. The phenomenon in Semarang Regency was the tendency for school-age children to be overweight. This overweight event indeed occurs several times. Child age is a vulnerable phase in nutritional problems because this causes the onset of a disease at the next age. This community service aims to increase understanding and skills in utilizing learning media through Edugame about my plate content. Method of Activity: This activity was carried out from the 3rd of June to the 3rd of July 2023 in Genuk district, Semarang Regency. The results of the questionnaire about the knowledge before and after the activity were analyzed using univariate analysis of frequency distribution. This community service activity was done in Posyandu (Integrated Services Post) for under-five children by involving village midwives, cadres, and 11 mothers having under-five children. Results: The results of this community service show that knowledge is increasing about my plate content after counseling or socialization. Discussion: This Edugame can be used as a media for health education to help the community increase understanding of a theme. This Edugame can be used to overcome the saturation of recipients of information, especially toddlers: it helps learn, motivates, fun educational media, and can increase creativity.
Online Vs Offline: Comparison of Effectiveness of PhET Simulation and Science KIT in Junior High School
Authors: Nikmah Firda , Maison Maison , Syamsurizal Syamsurizal
Published: October 2023

Purpose of the study: This study aims to compare the effectiveness of online and offline simulation media. Especially during the transition period from the new normal, hybrid learning and back to the new normal.

Methodology: The research design used was quasi-experimental. The study sample was taken using a random sampling technique. The data collection techniques used are observation and tests. Observation is carried out to find out more about the subject of research. A trial is conducted to determine the condition of students before and after receiving treatment. There are two test instruments used, namely pretest and posttest. The treatment given to the control class is learning using Science KIT, and the experimental class will use PhET Simulation. The results of the study will be processed using SPSS.

Main Findings: PhET media and science KIT based on the N-gain test proved to increase on average after treatment. In the control class, the gain value was 0.7, while the gain value was 0.8 in the experimental class. According to the criteria, both classes are in the high category. but in contrast to the percentage of effectiveness, the use of PhET is effective with a rate of 86%, while KIT science is quite practical with a ratio of 71%.

Novelty/Originality of this study: PhET simulation media and science KIT can explain abstract material to improve cognitive understanding. The use of this simulation media can be adjusted to learning conditions. if offline, use KIT, and if online, use PhET.
Secondary School Students’ Perception of Science Laboratory Accident Status and Preventive Measures in Awka Education Zone
Authors: Nwune Emmanuel Chibuike , Oguezue Nnaemeka Kenechi , Odum Blessing Ifeoma
Published: October 2023

Purpose of the study: The study investigated secondary school students’ assessment of science laboratory accident status and preventive measures in the Awka Education Zone. Two research questions guided the study, and one hypothesis was tested at a .05 significance level.

Methodology: The study used the descriptive survey research design. A sample of 156 public and 40 private secondary school students was used. A checklist and a questionnaire were used to collect data. The questionnaire was validated, and a Cronbach Alpha reliability test gave a coefficient of 0.86. The collected data was used to analyze mean, standard deviation, percentage, and t-tests.

Main Findings: The results revealed that science laboratory accidents do not occur in secondary schools in Awka Education Zone, irrespective of school type. The study also observed no significant difference in the preventive measures against science laboratory accidents adopted by private and public secondary school students in the zone.

Novelty/Originality of this study: There is limited literature in the present study’s area seeking to assess the laboratory accident status in secondary schools and the measures the students take to avert these accidents. Thus, the present study’s findings would provide background information on laboratory activities and accidents in the area of the research and preventive measures to be deployed.
Description of Teacher Responses to the Implementation of Student Process Skills Portfolio Assessment
Authors: Harizon Harizon , Asrial Asrial , Haryanto Haryanto , Ernawati M. Dwi Wiwik , Kurniawan Dwi Agus , Sinaga Feliza Paramitha , Haryati Rizki
Published: October 2023

Purpose of the study: This research aims to describe the response of science subject teachers to the assessment of students' process skills portfolios.
Methodology: The research method used in this research is mixed, namely a combination of qualitative and quantitative methods. The research design chosen was a sequential explanatory design. This design was selected because quantitative research was carried out first and followed by qualitative methods. This design ensures that the quantitative data obtained is strengthened with qualitative data. Quantitative data analysis techniques are carried out using descriptive statistics. Meanwhile, qualitative data was analyzed based on Miles and Huberman's theory. The instrument used to collect quantitative data is a questionnaire sheet to measure teacher responses in portfolio assessment. Meanwhile, qualitative data was obtained from interviews and documentation studies on relevant problems. The population of this research is schools in Jambi Luar Kota District. The research sample is science subject teachers. The sampling technique used was cluster random sampling.
Main Findings: The results obtained are the teacher's response in State Junior High School 1 Muaro Jambi superior to State Junior High School 1 Atap Pematang Jering.
Novelty/Originality of this study: The urgency of this research is seen from the importance of assessment in learning activities, which is a tool for measuring student abilities and evaluating the education system. The background of this research is limited by the sample involved being only science subject teachers, and the population chosen is the Jambi Luar Kota sub-district.
Climatic-Geomorphological Investigation of the World's Wettest Areas around Cherrapunji and Mawsynram, Meghalaya (India)
Authors: Pareta Kuldeep , Pareta Upasana
Published: October 2023

This research paper comprehensively examines the climate and geomorphological features of Cherrapunji and Mawsynram, aiming to understand the factors and environmental implications of their extreme precipitation. The study investigates climatic patterns, identifies geomorphological characteristics, and explores the factors influencing the occurrence of heavy rainfall in these areas, and displays unique rainfall patterns with high precipitation levels and notable spatio-temporal variation influenced by topographic interactions. Trend analysis reveals stable rainfall conditions over the past 122 years. The shift of the world's wettest place from Cherrapunji to Mawsynram in recent decades have been attributed to various factors such as geographical location, geomorphology-local topography, LULC-human influence, rain shadow effect, and orographic lifting effects. Cherrapunji recorded maximum rainfall of 24.55 thousand mm, while Mawsynram received 26 thousand mm of rainfall in the last century. The analysis of long-term rainfall data indicates distinct dry and wet seasons, with recent trends (2000-2020) suggesting a decline in rainfall for both locations. Furthermore, extreme value analysis techniques are employed to estimate maximum rainfall for different return periods, offering insights into extreme rainfall events. The return period of one day's highest rainfall of 1340.82 mm is about 100 years. The findings contribute to our understanding of climate change impacts, support sustainable development practices, and inform strategies for water resource management and erosion mitigation in similar geographic contexts. This research enhances our knowledge of these unique regions and their significance within the broader context of global climate systems.
Effect of Oligomers and Polymers of Ethylene Glycols on Micellar Characteristics of Aqueous Solutions of Sodium Pentadectyl Sulfonate
Authors: Barkhudaryan Vigen
Published: October 2023

The influence of oligomers and polymers of ethylene glycols with a different molecular mass on the structural transformations of aqueous solutions of surfactant, sodium pentadecylsulfonate, studied by viscometry and light scattering methods depending on their content in the system. It established that ethylene glycol with a molecular mass of 2,000 and 40,000 does not affect the structure of the system. For ethylene glycol with a molecular mass of 4,000, 6,000, and 20,000, a clearly expressed complex course of the dependence of the intrinsic viscosity of the micelle system on the polymer content was established. It assumed that with the changes in the concentration of ethylene glycols in the system, micelles are compacted due to a change in the balance of hydrophobic-hydrophilic interactions. In parallel with the change in apparent micelle masses and asymmetry coefficients determined by the light scattering method, the intrinsic viscosity also changes depending on the system's composition. The practical application of this research is that it allows the performance properties of sodium pentadecyl sulfonate (SPDS) to be adjusted, thereby expanding and improving its applications.