bluuebunny/crossref_metadata_2025 huggingface dataset:
CD34+ hematopoietic progenitor cells enumeration and mononuclear cell count: an experience from a tertiary care centre
Authors: Bhat Shuaeb , Hussain Saleem , Noor Huma , Shoket Nadeem
Published: January 2019

Background: This study was conducted to assess the CD34+ hematopoietic progenitor cells enumeration by flow cytometry and the utility of performing mononuclear cell count before performing the Stem cell enumeration. Collection was done on two consecutive days with CD34+ hematopoietic progenitor cell enumeration of both the samples. Mononuclear cell counts were done in all the patients. The purpose of the study was to do counts directly from the leukapheresis pack and see the reliability of this practice.Methods: Samples were collected from the leukapheresis pack and subjected to mononuclear cell count and CD34+ hematopoietic progenitor cells enumeration by flow cytometty before harvesting.Results: A total of 66 samples from 34 patients were taken up for the study. 76.47% of our cases were that of multiple myeloma and 17.64% of the cases were that of non Hodgkin lymphoma and 2.94% cases each of neuroblastoma and Hodgkin lymphoma. It was noted that the mononuclear cell counts correlated well with the CD34+ HPC in most of the cases with MNC being above 4 x 108 per pack per kg body weight in cases where CD34+ HPC counts were more than the desired lower limit of 2 x 106 per pack per kg body weight.Conclusions: It was observed that flow cytometric enumeration of CD34+ hematopoietic progenitor cells directly from the leukapheresis pack gave satisfactory results even without doing peripheral blood CD34+ HPCs enumeration before leukapheresis. Also, in our study we were able to set a limit of mononuclear Cell at 4 x 108 per pack/kg BW as counts beyond that always correlated with the more accurate flow cytometric method of CD34+ HPC count of more than 2 x106 per pack/kg body weight, therefore acting as a crude method for assessing the mobilization.
Resistance pattern of methicillin resistant Staphylococcus aureus among nasal isolates of HIV infected patients in a tertiary care hospital
Authors: Diwakar Manish Kumar , Goyal Ankur , Goyal Sapna
Published: January 2019

Background: Patients infected with HIV have an increased risk of nasal Staphylococcus aureus carriage as well as consecutive staphylococcal infections and is a major reservoir for MRSA which is potential risk factors for community acquired MRSA. Knowing the Nasal carriage status of Staphylococcus aureus and their Antibiogram will be beneficial for effective management of these patients.Methods: Nasal swab sample were collected from all the participants and processed for culture and identification of Staphylococcus aureus and their antimicrobial sensitivity. All the Staphylococcus aureus isolates were tested for Methicillin resistance by Oxacillin screen agar test, cefoxitin disc diffusion test and further confirmed by mecA gene PCR.Results: In this study out of 220 HIV seropositive patients, 43.64% isolates were confirmed to be S. aureus, 18.75% MRSA and 81.25% were MSSA. Cefoxitin disc diffusion showed 100% specificity (95% CI; 97.05%-100.00%), 100% sensitivity (95% CI; 83.89-100.00%) and 100% accuracy (95% CI; 97.47% to 100.00%) while comparing with gold standard mecA gene PCR. Among the nasal carriers; males (60%) ware dominant on females (40%). 31-50 years age group was strongly associated with MRSA nasal carriage. None of the isolates were resistant against lenozolid, teicoplanin and vancomycin while ampicillin (75%), ciprofloxacin (62.5%), clindamycin (59.38%) and cotrimoxazole (53.13%) showed increased resistance against S. aureus nasal carriage.Conclusions: Resistance among HIV positive persons for all antibiotics showed statistically significant while compared to control group. Cefoxitin disc diffusion can be used as surrogate agent for mecA gene detection.
Alcohol and tobacco induced infiltrating ductal carcinoma male: a case report
Authors: Yadav Akhila Janga , Chowdary Bhavana Pamulapati , Yadav Divya Bharathi Jekkula , Penthala Rajender , Bonkuri Vineeth
Published: January 2019

Male breast cancer is a rare cancer that forms in the breast tissue of men, it accounts for 1% of all the cancers in men. Recent epidemiological studies suggest that the incidence of MBC is increasing by 1.1% per year.  Due to lack of knowledge and awareness, MBC cases are diagnosed lately, mostly during stages III /IV. Early detection and reduction of mortality and morbidity related to male breast cancer is essential. The present article provides a detailed study of a patient with Infiltrating ductal carcinoma, grade III with regional nodal metastasis and the patient is positive for both oestrogen and progesterone receptors. In this case the patient is alcoholic and had habit of chewing tobacco since childhood and one of the patient’s relative had female breast cancer. These are the probable risk factors in this particular case. The better knowledge regarding the male breast carcinoma can be obtained through the thorough study of the available male breast cases.
Giant perivascular spaces: two case reports
Authors: Qi Yuying , Han Xiaofeng , Lu Shujun , Ma Wenbin , Chen Panpan , Wang Xuezhen
Published: January 2019

Giant perivascular spaces or Virchow-Robin spaces (VRSs) are uniquely inherent developmental malformation and are generally lined by ependymal or leptomeningeal cells. The cerebral hemispheres with VRSs present multiple cysts of curvilinear, round, oval, or layered configuration, which have the same signal intensity as the cerebrospinal fluid (CSF) and represent extremely dilated VRSs. The cortex became extremely thin with a well-defined margin. Herein, we report two cases of true giant perivascular spaces and present a review of pertinent literature. A patient has multiple cysts in the unilateral and bilateral and has polycystic liver. The clinical presentation, image logical features, and diagnosis are discussed.
Inherent irreversibility impacts on thermal boundary layer flow over a mobile plate with convective surface boundary conditions
Authors: Haider Sajjad , Butt Adnan Saeed , Ali Asif , Li Yun-Zhang , Hussain Tufail
Published: January 2019

Background: The irreversibility impacts on flow and heat transfer processes can be quantified through entropy analysis. It is a significant tool which can be utilized to deduce about the energy losses. The current study investigates the inherent irreversibility impacts during a flow of boundary layer and heat transfer on a mobile plate.

Methods: The flow is examined under thermal radiation and convective heat conditions. The fundamental governing equations of flow and heat phenomenon are transmuted into ordinary differential equations by employing similarity transmutations and shooting technique is utilized in order to solve the resultant equations. The temperature and velocity profiles are acquired to reckon Bejan and entropy generation number. Pertinent results are elucidated graphically for the movement of plate and flow in same and opposite directions.  

Results: A decline in temperature profile is noted with rise in values of Pr in both cases when the movement of surface and free stream is in similar and converse directions. A decrease in temperature is observed for both cases with increase in NR while with the rise in Biot number a, the temperature profile also increases. Entropy generation rate near the surface is high in case when surface and free stream are moving in opposite directions as compared to case when they move in same directions.

Conclusions: It is observed that irreversibility impacts are more remarkable when the movement of fluid and plate is in opposite direction. Moreover, irreversibility impacts of heat transfer are prominent in free stream region.

 
Clinico-microbiological aspects of tinea corporis in North India: emergence of Trichophyton tonsurans
Authors: Kaur Isampreet , Chaudhary Anuradha , Singh Harshvardhan
Published: January 2019

Background: Tinea corporis is a superficial fungal infection of the glabrous skin of the trunk and extremities caused by closely related organisms of the three genera of dermatophytes– Trichophyton, Microsporum and Epidermophyton. The prevalence of the different species varies according to geographic and climatic regions. This study was an attempt to find out the causative fungal agents in clinically suspected cases of tinea corporis.

Methods: During a period of six months from June 2017 to November 2017, various skin samples from clinically suspected cases of dermatophytosis were examined for presence of fungal elements using KOH preparation and culture on Sabouraud’s dextrose agar. The causative organisms were identified using conventional methods.

Results: A total of 157 skin samples were obtained and processed. The most common age group involved was 21 to 30 years of age with male to female ratio of 1.5:1. The patients of rural area (67%) predominated over urban (33%) with most of the patients presenting in the monsoon season (43%). The KOH positivity was seen in 51% and culture positivity in 50% of samples. The dermatophytes (62.9%) predominate over non-dermatophytes (37.1%) with Trichophyton tonsurans isolated as the commonest causative fungal agent.

Conclusions: Due to the great variation in the presence of fungal species in different places and at different times, mycological examination is necessary to diagnose, differentiate and treat dermatophytosis.
Dermatological life quality index in psoriasis out patients: the changing trend
Authors: Parimalam K. , Fathima S. Sanjeetha
Published: January 2019

Background: Psoriasis is a chronic inflammatory disease characterized by remissions and exacerbations, having great impact on social and psychological aspects. From mild plaque psoriasis to more severe pustular and erythrodermic forms with or without joint involvement, is known to have a negative impact on QOL (Quality of Life). Appropriate treatment will improve both disease outcome and QOL in patients. The objective of the study was to assess QOL in psoriasis patient of different age group, type, duration and severity of disease, and their response to this assessment.

Methods: A cross sectional study was done with pretested DLQI questionnaire on 101 psoriasis patients, in a government hospital. Interpretation of score and impact on QOL was done and graded as mild, moderate, considerable, severe and very severe.

Results: In our study, females outnumbered males with male female ratio of 1:1.5. The mean age 39.56±16.029 years. No significant association was noted between grade of affection and demographic variants. Most of them had moderate impact on QOL. QOL was worst affected in patients <5 years of disease duration. 85% of the patients felt happy & 15% felt neutral on being evaluated by this questionnaire.

Conclusions: It is suggested that DLQI is assessed in all new/patients with less than 5 years of disease. Appropriate systemic/photo therapy to be initiated even in mild disease if there is negative impact on the QOL. Assessment of QOL strengthens the doctor-patient rapport and improves better patient adherence to therapy and achieves faster and better control of the disease.
Cutaneous horn arising from a basal cell carcinoma of forehead: a case report
Authors: Sivaramakrishnan S. , Thomas Jayakar
Published: January 2019

The term cutaneous horn or “cornu cutaneum” is used to describe a well circumscribed usually conical hyperkeratotic mass arising from another cutaneous lesion. Several lesions have been reported to occur at the base of the keratin mass. Here we report a rare case of cutaneous horn arising from a basal cell carcinoma (BCC) over the forehead of a 52 year old female patient.

 
Rituximab as first line: an advent in pemphigus
Authors: Gopinath V. P. K. , Kolaparambath Basheer Ahammed , Simi V. M. , Rishad C. M. Ali , Farisa P. M. , Jose Tresy
Published: January 2019

Rituximab is a newly approved biological wonder drug in pemphigus vulgaris -an autoimmune mucocutaneous blistering disease due to antibodies produced against the epidermal adhesion molecules dsg 1 and dsg 2. The conventional therapy included high dose steroids or immunosuppressants that though effective had significant adverse effects that necessitated an alternate path in treatment. We present a case series of five patients in different clinical scenarios diagnosed with pemphigus vulgaris and treated with Rituximab by RA protocol either sole or in combination with other treatment strategies. Our experience with this drug has paved way to immense possibilities and outcomes that are in favour of using Rituximab as first line option. We have encountered prolonged remission in cases that were treated with Rituximab by Rheumatoid arthritis (RA) protocol. The sustained response has helped in reducing the dose of steroids and other immunosuppressants substantially. These facts are reinforced through our observations. But there is need to standardize the dosage of Rituximab in pemphigus.
Immunotherapy and Pancreatic Cancer
Authors: Allen Timothy , Shoja Ghazaleh , Court Naveed Basha
Published: January 2019

Pancreatic cancer is an aggressive and highly lethal form of pancreatic malignancy which is the fourth leading cause of cancer-related deaths in men and women in the USA. According to the American Cancer Society in 2014, it was estimated that about 46,420 people (23,530 men and 22,890 women) were diagnosed of pancreatic cancer. Additionally, in the same year about 39,590 people (20,170 men and 19,420 women) died of pancreatic cancer. It is highly observed men over women and also common with increasing age. The availability of new technology in diagnosis helps in the early detection of the pancreatic cancer. These technologies will serve as the primary requirement for management of disease. The exact cause of pancreatic cancer is not known, several risk factors had been indicated leading to pancreatic cancer. Immunotherapy has been a promising development in the past few years. The recent activities have increased the understanding of the tumor microenvironment, various immunotherapeutic modalities or combination therapy (such as chemotherapy with immunotherapy) had been applied in clinical trial. Additionally, the effects of such modalities in combination with immunotherapy in cancer patients are in still exploratory phase.
KIRGIZİSTANDA PARASAL AKTARIM MEKANİZMASI: EKONOMETRİK ANALİZ
Authors: MAZHİTOVA Akmaral , GÖK Barış
Published: January 2019

Bu
çalışmada Kırgızistan Merkez Bankasının parasal aktarım mekanizmalarından
geleneksel faiz oranı kanalı, banka kredi kanalı ve döviz kuru kanalı ele
alınmıştır. Kırgızistan'da para politikasının reel üretim ve fiyatlar genel
seviyesini hangi kanalla etkilediğini bulmak için VAR yöntemi kapsamında
etki-tepki ve varyans ayrıştırma analizleri, Ocak 2000'den Kasım 2016'ya kadar
olan aylık veriler kullanılarak yapılmıştır. Çalışma sonucunda, Kırgızistan’da
geleneksel faiz oranı kanalının fiyatlar üzerinde etkili olduğu ama milli gelir
üzerinde etkisiz olduğu sonucuna ulaşılmıştır. Kırgızistan gibi gelişmekte olan
ve dışa açık ülkelerde önemli rol oynamakta olan parasal aktarımın döviz kuru
kanalı enflasyon üzerinde etkili olmaktayken, reel gayrisafi milli hasıla
büyümesi üzerinde etkisiz kalmıştır. Banka kredi kanalı için yapılan analiz
sonucuna göre, hem enflasyon oranının hem de reel milli hasıla büyümesinin
bankaların reel kredi hacmindeki bir standart sapmalık şoka karşı tepkileri pozitif
yönde olmuştur.
Deficyty BRCA1 i syntetyczna letalność w białaczkach; nie tylko mutacje mają znaczenie
Authors: Piwocka Katarzyna , Podszywałow- Bartnicka Paulina , Skorski Tomasz
Published: January 2019

BRCA1 (breast cancer 1 susceptibility protein) is one of main regulators of cellular genomic stability. It is responsible for proper segregation of chromatides to daughter cells during mitosis as well as DNA double strand breaks repair by homologous recombination (HR). Genetic alterations of BRCA1 gene are cancer predisposition markers. Mutations or epigenetic alterations have been noticed in breast, ovarian and prostate cancers, significantly increasing risk of cancer development. Such gene alterations are not connected with leukemias. Importantly, BRCA1 deficiency is a factor which makes patients susceptible for personalized therapy with PARP1 inhibitors, which is based on the phenomenon called synthetic lethality. In this review we present our discoveries of novel mechanism leading to BRCA1 deficiency in leukemia, which is not connected with BRCA1 gene mutations or epigenetic alterations, but with attenuated translation of BRCA1 protein linked to the cellular stress response and controlled by RNA binding proteins. Moreover, we found that some treatments or genetic alterations in leukemias might also result in BRCA1 deficits. Our studies provide evidence that PARP1 inhibitors should be considered as efficient treatment in BRCA1-deficient leukemias, leading to elimination of cancer cells, includingstem and progenitor cells. Finally we propose a strategy to select leukemia patients which might be sensitive to therapy with PARP1 inhibitors.
Epigenetyczna regulacja ekspresji genów â nowy mechanizm łączący otyłość z rozwojem cukrzycy typu 2
Authors: Dobosz Aneta M. , Dziewulska Anna , Dobrzyń Agnieszka
Published: January 2019

Type 2 diabetes (T2D) is a complex disorder that is caused by a combination of genetic, epigenetic, and environmental factors. Î˛-cell failure and insulin resistance in peripheral tissues that are induced by lipid overload are main hallmarks of T2D. The mechanisms that link obesity-driven alterations of lipid metabolism and T2D are still elusive, thereby impeding the development of effective prevention and treatment strategies. Although genetic variants that have been identified in high-throughput studies comprise an appreciable proportion of the genetic component of T2D, they explain < 20% of the estimated heritability of T2D. A growing body of evidence suggests an intrinsic role for epigenetic modifications in the pathogenesis of T2D. The epigenetic regulation of gene expression in tissues that play a key role in the obesity-related development of T2D has been demonstrated, including PDX1 in pancreatic islets, PPARGC1A in skeletal muscles, ADIPOQ in adipose tissue, and TXNIP in the liver. The present review summarizes our current knowledge of crosstalk between the epigenetic control of gene expression, particularly via DNA methylation, toxiclipid mediators, and the pathogenesis of obesity-related T2D.
Rola desaturazy stearoilo-CoA w regulacji metabolizmu serca
Authors: Tabaczar Sabina , Wołosiewicz Marcin , Filip Anna , Olichwier Adam , Dobrzyń Paweł
Published: January 2019

The uptake and utilization of energetic substrates in the myocardium are under strict control, any disturbances of which may lead to myocardial dysfunction, such as in the case of ischemia and heart failure. Stearoyl-CoA desaturase (SCD) is an enzyme that converts saturated fatty acids to monounsaturated fatty acids. It is an important player in the regulation of heart metabolism. Our previous studies showed that SCD1 affects substrate utilization by the heart, with a preference for glucose. Large cohort studies established a positive correlation between the plasma fatty acid desaturation index and cardiovascular disease mortality. Therefore, SCD1 might serve as a potential target for future therapies. We review recent findings on the role of SCD1 in the heart, with a focus on cardiac metabolism reprogramming and its involvement in heart dysfunction.
Mitochondrialne kanały potasowe: podsumowanie
Authors: Szewczyk Adam , Bednarczyk Piotr , Jędraszko Justyna , Kampa Rafał Paweł , Koprowski Piotr , Krajewska Milena , Kucman Shur , Kulawiak Bogusz , Laskowski Michał , Rotko Daria , Sęk Aleksandra , Walewska Agnieszka , Ĺťochowska Monika , Wrzosek Antoni
Published: January 2019

Mitochondria play a fundamental role in ATP synthesis within the majority of mammalian cells. Potassium channels present in the inner mitochondrial membrane arefine regulators of mitochondrial function, based on inner membrane K+ permeability. These channels are regulated by a plethora of factors and conditions in a way similar to plasma membrane potassium channels. Regulators of mitochondrial potassium channels include the membrane potential, calcium ions, free fatty acids and ATP levels within the cells. Recently, it was shown that these channels are regulated by the respiratory chain, stretching of the membrane and phosphorylation. The essential interest that has driven studies of mitochondrial potassium channels for nearly 25 years is their role in cytoprotection and in cell death. Mitochondrial potassium channels have been described in neurons, astrocytoma, cardiac and skeletal muscles, fibroblasts, keratinocytes and endothelial cells. In this overview,we summarize the current knowledge of mitochondrial potassium channels. This summary will be done with a special focus on studies performed over the last 20 years in the Laboratory of Intracellular Ion Channels at the Nencki Institute. These include studies on the electrophysiological and pharmacological properties of mitochondrial potassium channels and on their regulation by endogenous intracellular substances. Additionally, the regulation of mitochondrial potassium channels by the respiratory chain and by stretching of the inner mitochondrial membrane will be reviewed. Properties of mitochondrial potassium channels in various organisms will also be summarized.
Choroby mitochondrialne, postęp w badaniu i leczeniu
Authors: Bartnik Ewa , Tońska Katarzyna , Rusecka Joanna
Published: January 2019

Choroby mitochondrialne wynikają z nieprawidłowej funkcji mitochondrialnego systemu fosforylacji oksydacyjnej: łańcucha oddechowego i syntazy ATP, produkującego energię komórkową w formie ATP. Jest to zróżnicowana grupa chorób dziedzicznych o szerokim spektrum objawów klinicznych mogących pojawić się w każdym wieku. Mogą one być wynikiem mutacji zarówno w mitochondrialnym DNA, jak i DNA jądrowym. Duża zmienność fenotypu pacjentów utrudnia ich diagnozowanie. Ostatnie osiągnięcia w dziedzinie diagnostyki i badań genetycznych oraz nowe metody reprodukcyjne są ogromną szansą na poprawę diagnostyki, leczenia i ograniczenie chorób mitochondrialnych. W tej pracy przedstawiono nowe zagadnienia pozwalające lepiej zrozumieć etiologię tych chorób oraz postęp w ich diagnozowaniu.
Menuju Sekolah Ramah Anak Holistik-Integratif Melalui Learning Organization
Authors: Puspitasari Intan Nuyulis Naeni
Published: January 2019

The facts about the increasingly turbulent cases of children make education. institutions more serious about running child-friendly schools (SRA). The term SRA contains a meaning that is still very abstract and needs technical-political arguments as well as patterns of systematic application to describe it. Therefore, through the learning organization (LO) with the theoretical approach of The Fifth Discipline Peter M. Senge and Organizational Learning Model Michael J. Marquardt can further produce visionmission alignment, the formation of mental models and system thinking, as a very integral part in building understanding and implementation of SRA in a more holisticintegrative manner. Because solving wholly various cases and integrated certainly cannot be done alone, cooperations with many parties, both in the scope of micro, meso, exo and macro are necessarily allied. This becomes a responsive step as well as preventive way against various acts of crime and violence in children around us
The Insights of Glocalization In Islamic Primary Education
Authors: Suci Dewi Nur , Puspitasari Intan Nuyulis Naeni
Published: January 2019

The expansion of internationalization has challenged education advancement in 21th century which is not only at Islamic higher education level but also at the Islamic primary education sphere. For preparing young learners to engage in the dynamics of internationalization, some Islamic primary schools competitively share new horizons on integrating sciences, humanism and spiritual values that adapt salaf models of pesantren and global ideas. Therefore, this article, in a qualitative research, exemplifies the social phenomena on how to construct new paradigm of glocalization for the evolvement andperpetuation of Islamic primary educational institution in Indonesia. Collected by observations, interviews and documentations, it is concluded that glocalization can be employed as the panacea for society’s needs in which local wisdom can take its portions in curriculum that inserts multiple intelligence and Higher Order Thinking Skill (HOTS) and provide academic agendas of primary instructional classroom.
Artikel Penyelesaian Sengketa Laut Antara Indonesia dan Malaysia di Wilayah Selat Malaka Menurut Hukum Laut Internasional
Authors: Yuseini Maulidya , Rachmawati Dian , Yuardini Fransiska , Syaifuddin Hafidh Lukmam
Published: January 2019

Abstract

Dispute settlement between Indonesia and Malaysia in the Malacca Strait Region started with the unilateral claims of both countries. The prevailing these unilateral claims resulted in the area of Exclusive Economic Zone in the Malacca Strait to overlap. UNCLOS 1982 is the existing International Law of the Sea and both countries ratified to this Convention. The purpose of this article is to find out how to resolve sea border disputes between Indonesia and Malaysia in the Malacca Strait Region under the Law of the International Sea. This article is also aimed to provide a narrative to the factors underlying the existing maritime border dispute.

Keywords: Disputes settlement, Malacca Strait, Overlapping
Sistem Pemidanaan dalam Perkara Pidana Pencabulan terhadap Anak: Studi Putusan Nomor: 535/Pid.sus/2015/PN.Bls
Authors: Antika Santi Dewi , Tanuwijaya Fanny , Martua Samosir Samuel Saut
Published: January 2019

As the nation's future generation, children have the right to a protected environment, as a lack thereof endangers their growth. One form of child protection is specifically regulated in Law Number 35 of 2014 on the Amendment to Law Number 23 of 2002 on Child Protection (Child Protection Act). Decency crimes against children as in case Number 535 / Pid.sus / 2015 / PN.Bls, the judge drops Article 82 Paragraph (1) of the Child Protection Act. This article contains two problems, inter alia, the judge's decision in case Number 535 / Pid.sus / 2015 / PN.Bls  whether it is in accordance with Article 82 paragraph (1) or Article 81 Paragraph (2) of the Child Protection Law and whether the witnesses are examined in case Number 535 /Pid.sus/2015/PN.Bls complies with Article 171 of the Criminal Procedure Code (KUHAP). This study uses the method of legal research with conceptual approach. The results and conclusions obtained in the writing of this article states that the judge must be more thorough in proving the elements of the article, and examine the witness more carefully to see the provisions of Article 171 of the Criminal Procedure Code.

Keywords: Judge's decision, molestation, and child
FAKTOR-FAKTOR YANG MEMPENGARUHI KESULITAN BELAJAR PADA SISWA KOMPETENSI KEAHLIAN TEKNIK GAMBAR BANGUNAN
Authors: Astuti Karuniawati , Iriani Tuti , Handoyo Santoso Sri
Published: January 2019

This study aims to determine the factors that influence students' learning difficulties On Skill Of Competency Architecture Engineering (Case Study at SMK Negeri 4 South Tangerang) academic year 2043/2015. The research lasted for 2 months from Marct to April 2015.In this study, the writer uses the survey method. The population in this study was the architecture engineering students of grade X year 2014/2015, a total of 71 students. The data collection tool used in this study was a questionnaire. Trial questionnaire instrument conducted by15 respondents majoring in class XI skill of competency architecture engineering. The analysis of instrument trial and error was conducted on the validity and reliability (Cronbach Alpha), for the number of fixed statement items is 25 items and the reliability result r11 = 0.91.Based on the data from the percentage of the number of students, the results of this study indicate that the factors affecting students' learning difficulties are largely on the internal factors which are psychological factor indicators with sub readiness of students (over 51%) and subtalent of students (over 50%). Meanwhile, the external factors that affect students' learning difficulties are largely on the indicators of school environmental factors with sub methods used by teachers (over 50%) and sub relationships between students (over 50%).
STUDI ANALISIS GAYA BELAJAR SISWA YANG MENGACU MODEL GRASHA-REICHMANN PADA MATA PELAJARAN KELOMPOK KEJURUAN KELAS X SMK KOMPETENSI KEAHLIAN TEKNIK GAMBAR BANGUNAN
Authors: Suryaman Suryaman , Iriani Tuti , Handoyo Santoso Sri
Published: January 2019

This study was aimed to know the representation that refers to students' learning styles of Grasha Model-Reichmann in vocational subjects of 10th Grade of Vocational High School (VHS), Competency of Architecture Engineering. The study lasted from April to May 2015.This research is using a descriptive quantitative survey approach. The population in this study were all 10th students of 26 and 52 VHS of Jakarta with a total of 122 people. The sampling method is using the saturated sampling techniques with a total of 122 people. The techniques used for data collection are communication techniques and documentation. The instrument for students that are used in the form of a questionnaire from a total of 60 statements refers to Grasha-Reichmann Student Learning Style (GRSLS). The result is that there are 49 number of valid statement with very high reliability of (r11) = 0.96.Based on the research that has been done, the students' learning styles that is mainly used to the Subject of Building Construction is the collaborative learning style (78.93%), collaborative learning style (80.00%) for the Measure Soil Science Subjects, collaborative learning style (78.50%) for the Engineering Mechanics Subject, and participant learning styles (75.66%) for the Subject of engineering drawings.Results of interviews with teachers indicate that the Subject Building Construction, Measure Soil Science and Engineering Mechanics during the learning process using lecture while teaching style to the Subject engineering drawings using peer tutors. The difference between the student's learning style with teachers teaching style shows the results obtained by each student also had differences.
HUBUNGAN PENGETAHUAN DASAR KONSTRUKSI KAYU DENGAN HASIL BELAJAR PRAKTEK KERJA BANGKU DI SMKN 58 JAKARTA
Authors: Wulandari Hasty , Daryati Daryati , Karsono R
Published: January 2019

This study aims to explore relations in the knowledge base for thr theory and application of work practieson the bench so asto create the correspondence between the basic knowledge learned by practice to be implemented, therefore students need to get enough stock in the understanding of the sciences that are taught in subjects construction Work bench Wood and Practice.In this research, conducted research at the SMKN 58 Jakarta by using quqsy experimental method, and the sample consisted of class X Program Wood Constructions Engineering Expertise as many as 31 students. Instruments used in this study is a test. These instruments use objective tests with four alternative answers to 30 questions. Aspects are measured in this testknowledge, while for measuring the value of work practice used bench practice that has been done by the class X Program Technical Expertise in Wood Construction SMKN 58 Jakarta. Once the instrument is made then tested the validity and reliabilityof the students outside of the sample, because the studied samples in the selected schools to test the validity and reliability SMKN 1 Cibinong, after the validity and reliability analysis was then performed grain matter and techniques of data analysis, data analysis techniques used in this study is regression.Based on the studies indicates that there is a positive relations between the Knowledge Base Construction Wood Bench Practice Learning Outcomes. The degree of association between variables Knowledge Base Construction Wood Bench Work Practice Learning Outcomes can be seen from the value of the correlation coefficient (rxy) of 0.470. This illustrates that the relations between the Knowledge Base Construction Wood Bench Work Practice Learning Outcomes are linked. Knowlwdge Base Construction Wood only slightly contribute to the high and low result Intern Learning Bench, that means the higher the Knowledge Base Wood Construction students, the higher the bench Work Practice Learning Outcomes
STUDI TENTANG KREATIVITAS GURU DALAM KEGIATAN PEMBELAJARAN ILMU STATIKA DAN TEGANGAN PADA SMK NEGERI JAKARTA
Authors: Lestari Nurma , Neolaka Amos , Nasution Nira
Published: January 2019

This study aims to determine the operational levels Teacher Creativity In lessons activity of ilmu statika dan tegangan lesson in State SMK Jakarta. Place of research in State SMK Jakarta. The research method was descriptive survey. The sample is 5 teacher who teaching ilmu statika dan tegangan lesson in ten class. Teacher creativity in lessons activity data obtained through a questionnaire with Likert scale. Test results showed that 52 items found valid and reliable statement.The result of the research is teacher creativity in lessons have done quite creative. The conclusion is the higher teacher creativity in lessons activity it will assist students more focus and interest in lessons activity and result achievement as expected
IMPLEMENTASI KURIKULUM 2013 SMK NEGERI KOMPETENSI KEAHLIAN TEKNIK GAMBAR BANGUNAN DI DKI JAKARTA
Authors: Sumantri Hadi
Published: January 2019

This research was aimed in order to know the implementation of 2013 Curriculum at Contruction Technical Drawing Competence on the aspects of: (1) Teachersâ€™s standard of assessment, (2) The standard of teacher and education staff in this case the competence of teacher and headmaster, (3) The standard of facilities.

This research is comprise to desriptive and quantitative research. The populationo this research was the entire of State Vocational High Schools in DKI Jakarta which have implemented 2013 Curriculum. There were 3 schools as research sample which was gotten by simple random sampling method. The respondents consisted of 3 vice principals of Curriculum, 3 head of contructrion technical drawing competence, and 10 representative students of each teacher in the school. The data collection of this research was gotten by questionnaire, observation, and documentation.

The result of this research showed that the aspects of : (1) the teacherâ€™s standard of assessment at the schools whic implemented 2013 Curriculum reached the average 83 % in very good criteria, (2) the standard of teachers and education staff reached the average 83 % in very good criteria for teachers competence, and the average 73 % in good criteria for headmaster competence, (3) the standard of facilities that support the implementation of 2013 Curriculum reached the average 94 % in very good criteria
Penerapan Model Pembelajaran Kooperatif Tipe Think Pair Share (TPS) untuk Meningkatkan Hasil Belajar Mekanika Teknik Siswa Kelas X TGB di SMK Negeri 26 Jakarta
Authors: Mustiani Shinthia , Iriani Tuti , Arthur Riyan
Published: January 2019

Tujuan Penelitian ini bertujuan untuk mengetahui penerapan model pembelajaran kooperatif tipe Think Pair Share (TPS) dalam meningkatkan hasil belajar mata pelajaran mekanika teknik pada siswa kelas X TGB di SMK Negeri 26 Jakarta. Penelitian berlangsung Maret sampai dengan Mei 2016.

Penelitian ini menggunakan Metode Penelitian Tindakan (Action Research) sebanyak tiga siklus. Setiap siklus terdiri dari empat tahap yaitu perencanaan, pelaksanaan, pengamatan dan refleksi. Subyek dalam penelitian ini adalah siswa kelas X TGB 1 SMK Negeri 26 Jakarta. Teknik yang digunakan dalam pengumpulan data adalah tes, observasi, catatan lapangan dan dokumentasi. Indikator keberhasilan dalam penelitian ini apabila penguasaan materi peserta didik mencapai 75% dari tujuan yang seharusnya dicapai, dengan Kriteria Ketuntasan Minimal 66.

Hasil penelitian ini menunjukan bahwa penerapan model pembelajaran kooperatif tipe Think Pair Share (TPS) dapat meningkatkan hasil belajar Mekanika Teknik siswa. Hal ini dibuktikan dengan adanya peningkatkan rata-rata hasil belajar siswa dari pre test ke post test, peningkatan rata-rata hasil belajar yang terjadi pada siklus I sebesar 25,47. Peningkatan rata-rata hasil belajar yang terjadi pada siklus II sebesar 26,09. Sedangkan peningkatan yang terjadi pada siklus III sebesar 26,41. Hal ini menunjukan bahwa model kooperatif tipe Think Pair Share (TPS) dapat digunakan sebagai salah satu model pembelajaran untuk meningkatkan hasil belajar mekanika teknik.
Evaluasi Pelaksanaan Bimbingan dalam Praktik Keterampilan Mengajar Terhadap Mahasiswa Fakultas Teknik Universitas Negeri Jakarta
Authors: Daryati Daryati
Published: January 2019

Research aim is to understand the extent of relevance teaching matter in the studying to become with matter teaches at smk the technical expertise building.Research done to suggest course education building technique engineering faculty jakarta state university in determining teaching matter who would be taught, so teaching matter in learned on a course education building technique engineering faculty jakarta state university relevant to the matter teaches in learn in schools.The research in course education building technique engineering faculty jakarta state university.

Time research on november 2017 - december 2017 .Research methodology uses the method descriptive qualitative .Technique data collection used analysis the content and direct interview .

The results of the study is showed the value of relevance matter teaching lecture majors in course of study education technique building of engineering faculty jakarta state university with matter teaching in smk program expertise technique building as big as 93,33 % the subjects drawing technique, 88,89 % for the mechanics technique, 91,67 % for the construction of buildings, 100 % for the science of measuring land, to draw interiors and exterior not relevant, 42,11 % to draw the construction of buildings 1 and 2, 81,82 % for construction reinforced concrete, 84,21 % for the construction of masonry, 45,45 % for finishing building, for the implementation of wooden construction, finishing wood and technology wooden construction not relevant.
Permian Basin Production Performance Comparison Over Time and the Parent-Child Well Study
Authors: Xu Tao , Zheng Wei , Baihly Jason , Dwivedi Priyank , Shan Dan , Utech Randy , Miller Grant
Published: January 2019

More operators are increasing their activity level in shale oil plays as the commodity price has stabilized. Activity has been at a fever pitch in the Permian Basin where over half of the North American land rigs drilling for oil are located. Operators realize that well performance varies both positively and negatively along reservoir quality and completion design changes as well as the drilling time of infill wells. Previous studies included investigation of the average type curve for gas wells located in core areas of various unconventional plays across the US. The Permian Basin is predominantly an oil-rich basin with multiple benches; the challenge associated with discerning which bench a well was landed in makes it difficult to compare completions. This paper seeks to generate decline trends for wells drilled in the Wolfbone and Wolfberry sequences of the Permian Basin while also examining the changes in completion evolution and parent/child relationships. A similar workflow from previous studies was also applied to generate the decline curves for wells by bench and producing year.

First, the horizontal wells were categorized based on which formation the laterals were landed in. Then, the moving window approach was used to identify the parent and child wells in each major formation. Based on this information, the production performance and completion between the parent and child wells were compared by bench and completion time.

In this paper, we investigated the change in decline rate by applying the ratio of best 1-month production (B1) and the best 12 consecutive months (B12) production rate with relation to parent and child well spacing across respective formation layers. We also examined the completion factors in combination with the child/infill well production performance to determine the production improvement and degradation causes, thereby providing a reference for child/infill well design.
Right-Sized Completions: Data and Physics-Based Design for Stacked Pay Horizontal Well Development
Authors: Tanner Kevin V. , Dobbs Walter C , Nash Steven D.
Published: January 2019

In some basins, large scale development of unconventional stacked-target plays requires early election of well targeting and spacing. Changes to the initial well construction framework can take years to implement due to lead times for land, permitting, and corporate planning. Over time, as operators wish to fine tune their development plans, completion design flexibility represents a powerful force for optimization. Hydraulic fracturing treatment plans may be adjusted and customized close to the time of investment.

With a practical approach that takes advantage of physics-based modeling and data analysis, we demonstrate how to create a high-confidence, integrated well spacing and completion design strategy for both frontier and mature field development. The Dynamic Stimulated Reservoir Volume (DSRV) workflow forms the backbone of the physics-based approach, constraining simulations against treatment, flow-back, production, and pressure-buildup (PBU) data. Depending on the amount of input data available and mechanisms investigated, one can invoke various levels of rigor in coupling geomechanics and fluid flow – ranging from proxies to full iterative coupling.

To answer spacing and completions questions in the Denver Basin, also known as the Denver-Julesburg (DJ) Basin, we extend this modeling workflow to multi-well, multi-target, and multi-variate space. With proper calibration, we are able generate production performance predictions across the field for a range of subsurface, well spacing, and completion scenarios. Results allow us to co-optimize well spacing and completion size for this multi-layer column. Insights about the impacts of geology and reservoir conditions highlight the potential for design customization across the play. Results are further validated against actual data using an elegant multi-well surveillance technique that better illuminates design space.

Several elements of subsurface characterization potentially impact the interactions among design variables. In particular, reservoir fluid property variations create important effects during injection and production. Also, both data analysis and modeling support a key relationship involving well spacing and the efficient creation of stimulated reservoir volumes. This relationship provides a lever that can be utilized to improve value based on corporate needs and commodity price. We introduce these observations to be further tested in the field and models.
Tying Horizontal Measurements to Well Performance Using Production Logs and Chemical Tracers in Multiple Wolfcamp Shale Wells, Delaware Basin
Authors: Green Larrez , Entzminger David , Tovar David , Alimahomed Adnan , Alimahomed Farhan , Defeu Cyrille , Malpani Raj
Published: January 2019

Historically, vertical wells were used to correlate formation tops and determine the lateral continuity of the reservoir. With the advancements in horizontal drilling and logging, the industry is able to gather an immense amount of information about the rock as we drill farther away from the vertical section. Numerous industry publications indicate that approximately 40% of the perforation clusters in hydraulic fracturing do not contribute to production. Many factors play a role in such production behavior, but the most important factor is the breakdown of perforations and propagation of the hydraulic fractures through them. Several methods, such as limited entry design and placing perforations in similar type rock, have been applied to mitigate this problem; the information needed for these methods is obtained from logging the laterals or using drilling data to determine rock properties. Diagnostic tools such as production logs, permanent downhole fiber optics, radioactive tracers, and chemical tracers have been deployed to understand the varying production profiles seen across the unconventional reservoirs.

This study focuses on three wells with lateral measurements to obtain petrophysical and geomechanical rock properties (one well in the Wolfcamp B and two wells in the Wolfcamp A). The wells also had pseudo rock properties calculated using surface drilling data. In most instances, the perforation clusters in each stage were placed in good reservoir and completion quality rock with the aim to minimize the stress differential between clusters. Different perforation schemes were tested in each of the three wells - number of clusters and spacing, limited entry, and geometric design. The wellbore geosteering profile, whether in or out of zone, was also considered in relation to the subsurface structure.

Lateral measurements in all wells showed the changing lithology and rock types across the lateral. The Wolfcamp B had a production log that indicated twice as many clusters contributing in the section of engineered perforations compared to the section where the perforations were placed using the gamma ray log. Time-lapse chemical tracers in other wells indicated changing production profiles. For example, early in the life of a Wolfcamp A well, the stages with clusters picked based on logs showed the highest production contribution compared to the geometric stages, but, later, the trend started to shift in favor of the geometric clusters. The geometric stages were in an area of the wellbore where the carbonate content was highest.

Comparisons of various data sets to production performance, such as the one included in this study, will provide some insight into the heterogeneous nature of the Wolfcamp shale and the impact of varying perforation techniques on production contribution from individual clusters.