bluuebunny/crossref_metadata_2025 huggingface dataset:
JUAL OBAT ABORSI PARE-PARE 081393076166 (ABORSI MANDIRI) OBAT ABORSI PARE-PARE
Authors: red alexa
Published: June 2020

CARA AMAN ABORSI MANDIRITujuan kami membuat situs ini adalah untuk membantu sesama yang mengalami masalah kehamilan yang tidak di inginkan.Entah karena sebab lain sehingga tidak menginginkan kehamilan itu, misalnya karena ikatan dinas, ikatan kerja, tidak ingin mengandung lagi karena anak masih kecil, karena “MBA” atau married by accident ataupun karena korban kebiadaban lelaki tak bertanggung jawab. Apapun alasan anda, kami akan membantu anda .Obat yang kami jual adalah hasil racikan resep dokter spesialis kandungan atau Obgin di Inggris dan Jepang.Dan di awasi oleh apoteker yang sudah berpengalaman bertahun-tahun. Obat penggugur kandungan yang manjur ini telah terbukti menolong ratusan orang yang ingin menggugurkan kandungan.Klinik Aborsi kami telah melayani ratusan orang di Indonesia ataupun di Luar Negeri, dengan kualitas obat yang super dan manjur, serta pengiriman sangat cepat dan cara pakai obat yang mudah sehingga menyebabkan banyak nya klien yang menyarankan teman atau keluarga nya yang mengalami musibah kehamilan tidak di inginkan untuk membeli di tempat kami.Di lengkapi dengan brosur petunjuk pemakaian dan secara mudah dan praktis. Jika anda mengalami permasalahan tentang terlambat datang bulan, dan ingin aborsi secara aman tanpa bantuan dokter dan ingin menggugurkan janin, silahkan kontak kami, akan kami bantu setiap saat hingga sukses.Jual Obat Aborsi asli Obat penggugur kandungan obat cytotec asli original produk pfrizer USA — Pil aborsi Telah terbukti aman dan ampuh menggugurkan kandungan / melunturkan janin terbaik sampai bersih tuntas.dengan obat aborsi cytotec asli.1.OBAT ABORSI 1 BULANPaket Tuntas Rp 800.000,-2.OBAT ABORSI 2 BULANPaket Tuntas Rp 1.200.000,-3.OBAT ABORSI 3 BULANPaket Tuntas Rp 1.500.000,-4.OBAT ABORSI 4–6 BULANPaket Tuntas Rp 2.000.000,-Untuk semua produk obat “OBAT ABORSI”, kami jamin 99% efektif dan berhasil jika diminum sesuai dengan aturan pemakaian dan sesuai dengan usia kandungan pemakai.TLP: 081393076166CHAT/WA:081393076166
Obat Aborsi Majalengka ( Asli ) 082314597755 Klinik Penjual Obat Penggugur Kandungan Di Majalengka
Authors: halomuji
Published: June 2020

Jual Obat Aborsi Majalegka, Jual Cytotec Majalegka, Klinik Aborsi Di MajalegkaOBAT ABORSI MAJALENGKA —  OBAT ABORSI AMPUH —  JUAL OBAT PENGGUGUR KANDUNGAN TUNTASObat Aborsi Ampuh 0823 1459 7755 | Jual Obat Aborsi | Obat Aborsi Cytotec | Obat Telat Bulan | Obat Pelancar Haid | Obat Penggugur KandunganAPOTIK : Kami Jual Obat Aborsi Ampuh Hub : 0823 1459 7755 | Jual Obat Aborsi Aman | Obat Penggugur Kandungan Cytotec Ampuh | Obat Pelancar Haid Tuntas. Dengan harga yang bisa anda pilih sesuai usia kandungan anda. Obat yang kami jual ampuh dan tuntas untuk menunda kehamilan atau proses aborsi untuk usia kandungan 1–6 BulanJual Obat Aborsi Cytotec Misoprostol Asli Usia 1 2 3 4 5 6 Bulan 100% TuntasKami jual Obat Penggugur Kandungan Ampuh untuk kehamilan dari umur janin 1 2 3 4 5 6 7 Bulan, Obat Penggugur Kandungan Asli Cytotec Misoprostol Pfizer Di Produksi Oleh Dokter Terkemuka Di AMERIKA PT PFIZER USA.Apa itu Aborsi ?“Abortion Adalah dengan membendung hormon yang di perlukan untuk mempertahankan kehamilan yaitu hormon progesterone, karena hormon ini di bendung, maka jalur kehamilan mulai membuka dan leher rahim menjadi melunak, sehingga mulai mengeluarkan darah yang merupakan tanda bahwa obat telah bekerja (maksimal 1 jam sejak obat diminum) darah inilah yang kemudian menjadi pertanda bahwa pasien telah mengalami menstruasinya, sehingga secara otomatis kandungan di dalamnya telah hilang dengan sendirinya 100% berhasil…https://www.linkedin.com/showcase/jual-obat-aborsi-majalengka* Paket Obat Telat Bulan — Obat Aborsi Standar 90% TingkatKeberhasilan* Paket Obat Telat Bulan — Obat Aborsi Tuntas 99% Tingkat Keberhasilanwebsite resmi : medicalobataborsi.blogspot.comLalu Anda Kirimkan SMS Ke Nomer Kami___________________________________.:: HUBUNGI ::..:: PEMESANAN LEBIH NYAMAN VIA SMS ::.Di No. Hp / WA : 0823 1459 7755Call : 082314597755
Dokter Jual Obat Aborsi Di Cikarang 082121994449 Cytotec Misoprostol
Authors: ORIGINAL OBAT
Published: June 2020

Jual Obat Aborsi Cikarang , Jual Cytotec Cikarang , Klinik Aborsi Di Cikarang , Obat Pelancar Haid Cikarang , Obat Penggugur Kandungan Cikarang , Obat Telat Datang Bulan CikarangOBAT ABORSI CYTOTEC  —  OBAT ABORSI AMPUH —  JUAL OBAT PENGGUGUR KANDUNGAN TUNTASObat Aborsi Ampuh 0821 2199 4449 | Jual Obat Aborsi | Obat Aborsi Cytotec | Obat Telat Bulan | Obat Pelancar Haid | Obat Penggugur KandunganAPOTIK : Kami Jual Obat Aborsi Ampuh Hub : 0821 2199 4449 | Jual Obat Aborsi Aman | Obat Penggugur Kandungan Cytotec Ampuh | Obat Pelancar Haid Tuntas. Dengan harga yang bisa anda pilih sesuai usia kandungan anda. Obat yang kami jual ampuh dan tuntas untuk menunda kehamilan atau proses aborsi untuk usia kandungan 1–6 BulanApa itu Aborsi ?“Abortion Adalah dengan membendung hormon yang di perlukan untuk mempertahankan kehamilan yaitu hormon progesterone, karena hormon ini di bendung, maka jalur kehamilan mulai membuka dan leher rahim menjadi melunak, sehingga mulai mengeluarkan darah yang merupakan tanda bahwa obat telah bekerja (maksimal 1 jam sejak obat diminum) darah inilah yang kemudian menjadi pertanda bahwa pasien telah mengalami menstruasinya, sehingga secara otomatis kandungan di dalamnya telah hilang dengan sendirinya 100% berhasil…Lalu Anda Kirimkan SMS Ke Nomer Kami___________________________________.:: HUBUNGI ::..:: PEMESANAN LEBIH NYAMAN VIA SMS ::.Di No. Hp / WA : 0821 2199 4449Call : 0821 2199 4449
Relación entre estilos de aprendizaje y desempeño académico en un programa de Instrumentación Quirúrgica
Authors: Arias Ortíz Wanderley Augusto , Ibáñez Pinilla Edgar Antonio
Published: June 2020

Introducción: el presente estudio pretende determinar la relación entre los estilos de aprendizaje y el desempeño académico de los estudiantes de instrumentación quirúrgica de una institución de educación superior en 2019. Métodos: estudio de corte transversal analítico en 148 estudiantes de II a VII semestre de un programa de instrumentación quirúrgica en Bogotá, a quienes se aplicó la prueba CHAEA y se indagó sobre su desempeño académico para observar la relación entre estos. Resultados: el estilo predominante fue el reflexivo 41,9% (n=62) y el desempeño promedio 3,84±0,24. No se encontró asociación entre estilos de aprendizaje y desempeño académico (p>0,05). Conclusión: no existe una relación estadísticamente significativa entre estilo de aprendizaje y desempeño académico, debido probablemente a homogeneidad entre los estudiantes.
STUDI TENTANG BANDENG PRESTO CRYSPY PADA INDUSTRI RUMAH TANGGA (IRT) “BU JENNI” DI KELURAHAN TUNJUNG SEKAR KOTA MALANG
Authors: Sudiyono Sudiyono , Sukamto Sukamto
Published: June 2020

Bandeng presto krispi merupakan salah satu produk pangan tradisonal masyarakat Jawa yang dimodifikasi dengan menambah krispi untuk menambah daya tariknya. Salah satu industri rumah tangga (IRT) yang memproduksi bandeng presto adalah Bu Jenni yang berlokasi di kelurahan Tunjung Sekar,kota Malang. Tujuan kegiatan adalah untuk mempelajari teknologi proses produksi dan manajemen sebagai upaya memperbaiki kualitas produk bandeng presto agar mampu meningkatkan daya saing dan segementasi pasar. Metode pelaksanaan kegiatan yang dilakukan pada bulan Juni sampai Desember 2019 dengan cara survey, wawancara langsung dan memberi solusi alternatif. Hasilkegiatan menunjukan bahwa proses produksi bandeng presto masih terbatas kapasitasnya yang menggunakan alat presto berkapasitas 5 kg. Bidang manajemen dan pemasaran produk mengalami peningkatan 10-20 persen pada tahun 2019 dibandingkan tahun 2018. Konsumen yang menjadi pelangga bandeng presto Bu Jeni masih bersifat lokal dan mulai berkembang keluar daerah sebagai oleh-oleh. Kesimpulan dari hasil kegiatan adalah bahwa produk bandeng presto sangat potensi untuk dikembangkan menjadi produk andalan usaha kecil menengah, di pasaran lokal maupun regional. Sedangkan sentuhan teknologi, manajemen produksi dan pemasaran perlu dikembangkan secara berkelanjutan.
Temperaturüberwachung und automatisierte Bestandsbuchungen im intelligenten Ladungsträgermanagement
Authors: Romer Martina , Zimmermann Michael , Meißner Sebastian
Published: June 2020

Kurzfassung

Durch die Integration von datenbasierten Dienstleistungen in unternehmensübergreifende Ladungsträgerkreisläufe erhoffen sich Unternehmen mehr Transparenz über ihren Materialfluss. In diesem Beitrag wird anhand des Aufbaus eines prototypischen Cyber-Physischen Systems am Technologiezentrum für Produktions- und Logistiksysteme (TZ PULS) gezeigt, dass durch intelligente Ladungsträger und cloudbasierte Service-Systeme eine Umsetzung von den datenbasierten Dienstleistungen „Temperaturüberwachung“ und „Automatisierte Bestandsbuchungen“ möglich ist. Die Ergebnisse geben Auskunft über die praktische Eignung der datenbasierten Dienstleistungen und zeigen technologische Grenzen auf, die bei der Implementierung in den logistischen Prozessen zu berücksichtigen sind.
Strain-rate dependent material properties of selective laser melted AlSi10Mg and AlSi3.5Mg2.5
Authors: Lutz Andreas , Huber Lukas , Emmelmann Claus
Published: June 2020

This paper investigates the mechanical properties of two selective lasermelted aluminum alloys (AlSi10Mg and AlSi3.5Mg2.5) under high strain-rate uniaxial loading. Accelerated tensile tests were performed under various strain-rate decades (.ε = 4.7 × 10-3 up to 250 s-1) to determine the load-speed-specific changes in the mechanical properties. As a result of the primary laser-based shaping process, the microstructure and characteristics change was entirely comparable to the conventional manufacturing of aluminum parts. Based on an ultrafine microstructure, parts achieve high strength along with a brittle fracture behavior. Modifications for applications requiring high ductility (e. g., the crashloaded structural parts of a car body) can be made through specific heat treatment strategies. The experimental results demonstrate that a significant increase in ductility (factors 4-5) with a concurrent decrease in strength can be obtained compared to the as-built state. In high-speed tests, the tensile strength of both alloys rose strain-rate dependently around 10 %, and the elongation at break increased relatively by ≈ 15 % for AlSi10Mg and ≈ 10 % for AlSi3.5Mg2.5.
Investigation of the influence of heat treatment of cold work steel on coating adhesion under mechanical load between substrate and thin titanium coatings deposited by PVD
Authors: Buttler Torben , Reiter Rolf , Wesling Volker
Published: June 2020

Metastable phases can be shifted to a different state by thermal loads on components. This leads to structural changes and precipitation. Within the scope of this investigation, a coating is applied to a solution annealed and a quenched and tempered substrate of the same chemical composition by means of a cold PVD process. The investigation is based on the process of polymer extrusion without additives. The substrate examined is 1.2379 tool steel. The substrate is used as a screw extruder material and is exposed to operating temperatures of up to 400 °C. A titanium layer is applied which is used in practice as an adhesion promoter and is in direct contact with the substrate. An annealing temperature above 500 °C results in special carbide hardening. These should show a worse layer adhesion than the metal bonds of the solution annealed sample. The aim is to investigate whether a difference is measurable or negligible. The loads during polymer extrusion are simulated by means of bending and pin-on-disk tests. The 3-point bending test simulates the mechanical load during extrusion. The pin-on-disk test simulates the friction between the extrusion screw flank and the extrusion cylinder. The substrate is characterized before and after sample preparation. Wear measurements are carried out using CLSM and SEM. The surface topography is recorded and then evaluated for comparison.
Effective hydrogen diffusivities of AISI 304 stainless steel with Ni or Au coating
Authors: Wannapoklang Krittayot , Leelachao Sirichai , Lothongkum Anchaleeporn W. , Lothongkum Gobboon
Published: June 2020

Metallic coatings which provide a hydrogen diffusion barrier are thought to reduce hydrogen assisted cracking on stainless steel. The influence of a metallic layer on the hydrogen migration of AISI 304 stainless steel was investigated using a commercial electroplating layer of Ni and Au on a thin stainless steel coupon. Phase identification was performed using an X-ray diffractometer to determine the average thicknesses, measured from back-scattered scanning electron images. Regarding the ASTM G148-97 practice, the effective hydrogen diffusivities of AISI 304 austenitic stainless steel, nickel and gold were measured as 7.07 × 10-13, 2.72 × 10-14 and 9.64 × 10-16 m2 × s-1, respectively. In this work, a gold layer was found to be most effective for the prevention of hydrogen diffusion when compared with untreated and Ni-plated 304 stainless steel.
Thermoforming behavior of 3D-printed PLA sheets
Authors: Eksi Olcay , Karabeyoglu Sencer Sureyya , Cinar Kenan , Muhurcu Aydin
Published: June 2020

Fused deposition modeling is one of the most well-known additive manufacturing methods. It might be considered the easiest way to produce particle reinforced composites or unreinforced sheets which are biodegradable and used in the packaging industry as well as for custom products. In this study, polylactic acid (PLA) sheets were produced by 3D printing and thermoformed using a lab-scale thermoforming machine. This article aims to determine the deformation behavior of 3d printed PLA sheets during thermoforming. In addition to experimental work, finite element analysis was performed to investigate the prediction capabilities of Mooney-Rivlin and Ogden models for PLA sheets. In addition, the initial thickness of the sheet was optimized using FEA and a python script to obtain final uniform thickness distribution. Thanks to 3D printing’s capability for printing sheets of variable thickness, sheets of variable thickness were printed to verify the material models. As a result, based on the thickness distribution obtained from the experimental study, Mooney-Rivlin and Odgen material models were found to be inadequate for representing the actual deformation behavior of PLA sheets.
Mechanical properties of dissimilar Ti-Al resistance spot welds
Authors: Ertan Rukiye
Published: June 2020

In this study, the mechanical behavior of titanium (ASTM Grade 2) alloy sheet, resistance spot welded with 5754 aluminum alloy, was investigated with respect to nugget formation and mechanical properties. The welding operations were performed using resistance spot welding at various welding currents (10, 12.5 and 15 kA), welding times (10, 15 and 20 cycles) and electrode forces (5, 10 and 15 kN). The weld nugget diameter and nugget center height, hardness, and tensile-shear test results of the welded samples were examined, and the mechanical properties were compared. As a result of the tests, it was seen that the welding parameters have a significant effect on the mechanical properties of the titaniumaluminum alloy welding joints. The tensile-shear load of the resistance spot welded joints increased as the welding current increased, and welding time increased for 15 cycles. On the other hand, when the electrode force increased, the tensile-shear load decreased markedly.
Wear and microstructural properties of coatings on Weldox 700 steel
Authors: Özorak Cihan , Okay Faik , Özorak Ebru , Islak Serkan
Published: June 2020

In this study, the wear and microstructure properties of some coatings produced on Weldox 700 steel were investigated via a high-velocity oxygen fuel (HVOF) technique. For the coating types, NiCrBSi, WCCo and CoNiCrAlY-based coatings were selected. Microstructure and phase formation were examined via scanning electron microscopy (SEM), X-ray diffraction and X-ray energy dispersive spectrometry. Wear tests of the substrate and coatings were made using the ball-on-disc method. It can be seen from the SEM images that the coating layers are metallurgically/ mechanically connected to the substrate and have a mostly homogeneous structure. The hardness measurement was taken from the top of the coatings. The hardness values of the coatings were significantly higher than those of the substrate. The coated substrates exhibit a very good tribological performance compared with the substrate. Depending on the load, the wear rate and coefficient of friction of the coatings were much lower as compared with the Weldox 700 steel substrate.
Optimum design of automobile components using lattice structures for additive manufacturing
Authors: Aslan Büşra , Yıldız Ali Rıza
Published: June 2020

In today’s world, reducing fuel consumption is one of the most important goals for the automotive industry. For this reason, weight reduction is one of the main topics in this research and for various companies. In this research, topology optimization was conducted on a suspension arm as a means of ensuring balance in automobiles. Subsequently, the model, formed by topology optimization was filled with a lattice structure and re-optimized by size optimization to obtain optimum dimensions for the model. These operations are described as lattice structure optimization. Additive manufacturing (3D printer) is necessary to produce complex models (after topology and lattice structure optimization). A static analysis of the new models was conducted by using the finite element method, and the results were compared with those of the initial design of the model. As a result of the comparison, positive results were obtained, and it was shown that topology optimization and lattice structural optimization could be used in the design of vehicle elements. According to the results obtained from lattice structure optimization, design structure can be formed more reliably than via topology optimization. In addition, both configurations and layouts of the cellular structures have a special effect on the overall performance of the lattice structure.
Kinetic characterization of boride layers formed on AISI 316 stainless steel
Authors: Aydın Özlem , Topuz Polat , Aydgomus Tuna
Published: June 2020

This paper presents the growth kinetics of the boride layer formed on a boronized AISI 316 (X5CrNiMo17-12-2) stainless steel surface. Samples were boronized applying the Ekabor 2™ boronizing agent in an atmosphere controlled furnace at 1073, 1173 and 1273 K for 1, 2 and 3 h by the powder pack method. Surfaces of the samples which have completed the boronizing process were prepared for metallographic examinations. An optical microscope and an integrated image analyzer were used to measure the thickness of the boride layer formed on the surface of the samples. Due to the dual phase structure of the boride layer formed on the steels in order to see these phases in detail, an SEM (Scanning Electron Microscope) image of the sample was taken with the help of the back scattered electrons. In addition, for determination of the elements constituting these phases, elemental analysis was carried out with the help of an EDS (Energy Dispersive Spectroscopy) unit connected to SEM. Then XRD (Xray diffraction analysis) analyses were carried out to understand in detail which phases formed the boron layer. For hardness measurements of boride layers, a Vickers hardness device with 100 g weight was used. Finally, to determine the growth kinetics of the boronized samples, calculations were made with the help of the Arhenius equation and compared with the literature.
Effects of graphene on the microstructure and properties of MAO coatings formed on AA7050
Authors: Xu Bo , He Yafeng , Wang Xiangzhi , Gan Weimin
Published: June 2020

Ceramic coatings were prepared on the surface of 7050 highstrength aluminum alloy using micro-arc oxidation in an aluminate electrolyte with added graphene. To analyze the surface morphology, roughness, phase composition, and corrosion resistance, scanning electron microscopy, X-ray diffraction, X-ray photoelectron, and electrochemical measurements were used, respectively. The addition of 9 g · L-1 of graphene to the electrolyte decreased the micro-pore size of the composite coatings and improved the density. In addition, with the addition of graphene, the roughness was the lowest, and the corrosion resistance was significantly improved.
Multilocular Cystic Nephroma: Is Radical Nephrectomy The Best Treatment In All Cases? Our Experience After 45 Years Working on a Tertiary Care Center
Authors: Fortes P. Ortolá , Durbá Agustín Serrano , Llopis Anna  Sánchez , Nebot Cinta Sangüesa , Carlos Domínguez Hinarejos , Baenas M. A. Conca , José Antonio March Villalba , Fortes P. Ortolá , Alba Polo Rodrigo
Published: June 2020

Introduction: Multilocular cystic nephroma (MCN) is a type of benign renal tumor that is sometimes
misdiagnosed with cystic Wilms Tumor. Given that each one has a different treatment, it is essential to make
a proper diagnosis.
Objective: Our aim was to find the differential characteristics of MCN and to be able to identify these renal
masses with low probability of malignancy, which are subsidiaries of a more conservative treatment.
Material and Methods: We conducted a retrospective descriptive study were we analyzed the patients with
MCN treated in our center between 1971 and 2016.
Results: We found 13 patients with a histological diagnosis of MCN, mostly males, with an average age of
46.8 months at the time of surgery. Clinically, 2 cases (15.4%) were asymptomatic, 6 had an abdominal
mass (46.1%), 3 had abdominal pain (23.1%) and 2 had hematuria (15.4%). The maximum diameter of the
mass was 7.3 cm (mean). 9 nephrectomies (69.2%) and 4 tumorectomies (30.8%) were performed. In two
of these (15.4%), neoadjuvant chemotherapy was administered due to presurgical suspicion of Wilms'
tumor, which was discontinued after the pathological analysis. In another 4 patients with suspicion of MCN,
all of them asymptomatic and with a tumor size <3cm, non-surgical treatment was decided. At the present
time all patients (operated or not) stay alive. No. cases of distant metastasis, local recurrence or mass
progression (in the non-operated patients) have been recorded.
Conclusion: Given its good prognosis, MCN can be treated with a non-radical surgery or even non-surgical
conservative treatment in selected cases. In our experience, the clinical and radiological characteristics are
the pillars to identify those patients with low risk of malignancy in which this attitude could be carried out.
Single Nucleotide Polymorphisms in Four Genes Associated with Survival Outcome for Patients with Head and Neck Squamous Cell Carcinoma
Authors: Wang Ren Sheng , Liu Chang , Mi Jing Lin , Xu Meng , Wang Ren Sheng
Published: June 2020

Background: This study aimed to use a bioinformatics pipeline to explore the underlying mechanisms and
identify genetic mutations that can be utilized to prognosticate individuals with head and neck squamous
cell carcinoma (HNSCC).
Methods: SNP-related data was accessed using the TCGA database. Mutation and expression analyses were
performed between the mutant samples and wild-type samples. Kaplan‐Meier analysis was conducted to
select the candidate mutant genes that affect overall survival. Correlation analysis, GSEA analysis and drug
sensitivity analysis of the candidate genes were performed.
Results: Down-regulation of FAT1, KMT2B, XIRP2 and ZNF347 expression were observed in the tumors
with mutations. Kaplan‐Meier analysis indicated that reduced levels of FAT1, XIRP2 was significantly
associated with better overall survival, while reduced levels of KMT2B, and ZNF347 were significantly
correlated to worse overall survival. Additionally, SNPs of the four genes were found to participate in
several pathways associated with HNSCC development. Furthermore, FAT1 mutation was sensitive to
several anti-tumor drugs, such as PI-103, Belinostat and Ruxolitinib.
Conclusion: SNPs in FAT1, KMT2B, XIRP2 and ZNF347 may be used as prognostic biomarkers in the
treatment of HNSCC.
Changing Pattern of Tuberculosis: Clinical Presentation Within a Decade - Analysis from South-East Europe
Authors: Škoro Matea , Alilović Marija , Lampalo Marina , Škoro Matea , Grle Sanja Popović , Trkeš Vesna
Published: June 2020

Introduction: Tuberculosis (TB) is an infectious disease from which people suffer even in the 21st Century.
According to official data for Croatia, the number of cases in the last decade has been decreasing.
Aim: Due to the triple reduction in incidence in the last ten years in Croatia, the purpose of this study is to
investigate whether patient characteristics have been changed, along with their comorbidities.
Material and Methods: This was a cross-sectional study where we treated 230 patients (62.1% male and
37.8% female) age 40-60 years with tuberculosis in 2003 and in 2013, we treated 70 patients (54.9% of men
and 45% women). Tuberculosis was diagnosed by direct microscopy of sputum, catheter aspirate, tumor
tissue, lymph node puncture, swab wound in 2003 and by direct microscopy of sputum samples, catheter
aspirates and bronchial washing samples in 50% of cases in 2013.
Results: In 2003, 95.2% of patients had pulmonary tuberculosis. Comorbidities were found in 63.8%. 51.3%
were smokers, 36.5% were alcoholics, diabetes and chronic obstructive pulmonary disease (COPD) was
found in 12.2% and tumors in 6.5%. After 10 years, 91.4% of patients had pulmonary tuberculosis. 90% of
them had comorbidities - 14.2% of patients had diabetes mellitus, 10% were treated for malignancies, COPD
was present in 8.5%. 31.4% were smokers, while alcoholism was found in 11.4%.
Conclusion: After 10 years tuberculosis has changed its face in South-East Europe. TB occurs more often
in the elderly population with comorbidities in 90% of cases (mostly diabetes mellitus, malignancies and
COPD). Men are no longer a risk group because women are affected almost equally. Clinical awareness of
the possibility of TB should be considered in patients with comorbidities, and active screening and
prevention should be undertaken
Multiple Tuberculomas in a Transplanted Liver Mimicking Metastases of Unknown Origin
Authors: McCormack Lucas , Agustín Angeramo , Florencia Antinucci , McCormack Lucas , Darío Ramallo , Julieta Rodriguez Catán
Published: June 2020

Liver transplant recipients are immunocompromised patients, and are often susceptible to bacterial, fungal
and virus infections. We report the case of liver-only tuberculomas occurring eleven years following a
deceased donor liver transplantation, that was initially interpreted as metastases of unknown origin.
Interestingly, only a few such cases have been reported, usually within the first two years after
transplantation, often when more aggressive immunosuppression is required. Although it is accepted that
tuberculosis incidence among solid organ transplant recipients is higher when compared with the general
population, its late onset after transplantation is very unusual.
From Neuroinflammation to Neuroprotection: Focus on Potential New Therapeutic Targets in Cognitive Impairment
Authors: Gareri Pietro , Cotroneo Antonino Maria , Gareri Pietro , Laura Manfredi Valeria Graziella
Published: June 2020

Neurodegeneration is closely linked to neuroinflammation. It is often associated with oxidative stress and
meaningful changes in cell energy metabolism. Neuroinflammation is due to non-neuronal cell activation
(microglia, astrocytes, mast cells) activation and proliferation. Also, it is associated with pro-inflammatory
substances release, able to modify synaptic plasticity. Microglia and astrocytes activation lead to toxic
agent’s release (reactive oxygen species, inflammatory cytokines); however, the final target of this process
is the cholinergic neuron. A number of substances can promote neuroprotection; recent scientific evidence
focuses on the role of sirtuins. In particular, SIRT1 is activated by caloric restriction, NAD biosynthesis and
different activators, called STACs (Sirtuin Activating Compounds). Citicoline is one of the most powerful
STACs. It has been widely shown to possess neuroprotective action, and lots of studies strengthened its
possible role.
Impact of Capital Inflows on Domestic Investment: Evidence from Panel Data
Authors: Mushtaq Mansoor , Shaheen Sania , Khan Irfan Hussain
Published: June 2020

Investment significance in any country cannot be ignored for its direct and indirect influences on the growth rate of the economy. Foreign capital inflows are one of the major determinants of domestic private investment. Hence, this study analyzes the effect of two kinds of foreign capital inflows, i.e. inward foreign direct investment and inward foreign remittances on domestic investment covering a sample of five South Asian economies from 1976 to 2017. The findings of the study reveal that both types of capital inflows raise the domestic investment and the role of remaining variables on investment is also positive and significant. The study recommended that steps should be undertaken to increase these foreign capital inflows to raise the domestic investment in these countries.
Real-life analysis of 280 patients with surgically treated acromegaly: a single-center experience from 2008 to 2015
Authors: Rotermund Roman , Mader Marius M. , Burkhardt Till , Matschke Jakob , Aberle Jens , Krajewski Kara , Flitsch Jörg , Rahvar Amir-Hossein
Published: June 2020

OBJECTIVE

The purpose of this study was to analyze the clinical and biochemical outcome of consecutive patients with acromegaly after microscopic transsphenoidal surgery (MTS) at a single center over an 8-year period.

METHODS

A retrospective analysis of patients with acromegaly treated via MTS between 2008 and 2015 at the authors’ center was performed. The mean follow-up was 29 months (range 1–120 months). Parameters investigated included tumor size, pre- and postoperative insulin-like growth factor–I, growth hormone levels, pretreatment, perioperative complications, and clinical outcome.

RESULTS

A total of 280 patients with acromegaly were treated surgically at the authors’ center over the abovementioned time frame and were included in analyses. For 231 of these patients, complete follow-up data were available for evaluation. One hundred eighty-eight patients (81%) showed remission initially according to current criteria. So far, 23 of these patients relapsed in the further course, so that on follow-up 165 patients (71%) demonstrated full remission by surgery alone. Most patients in whom remission after surgery failed were treated with somatostatin receptor ligands and/or dopamine agonists as second-line treatment. The main postoperative complications included transient hyponatremia and diabetes insipidus (13/280; 4.6%). CSF leakage only occurred in 2 cases (2/280; 0.7%). No surgery-related death occurred.

CONCLUSIONS

The data underline the effectiveness of MTS in acromegaly. Many patients with recurrent disease or incomplete tumor resection can be successfully managed pharmacologically.
Impact of tumor characteristics and pre- and postoperative hormone levels on hormonal remission following endoscopic transsphenoidal surgery in patients with acromegaly
Authors: Cardinal Tyler , Rutkowski Martin J. , Micko Alexander , Shiroishi Mark , Jason Liu Chia-Shang , Wrobel Bozena , Carmichael John , Zada Gabriel
Published: June 2020

OBJECTIVE

Acromegaly is a disease of acral enlargement and elevated serum levels of insulin-like growth factor–1 (IGF-1) and growth hormone (GH), usually caused by a pituitary adenoma. A lack of consensus on factors that reliably predict outcomes in acromegalic patients following endoscopic endonasal transsphenoidal surgery (EETS) warrants additional investigation.

METHODS

The authors identified 52 patients with acromegaly who underwent an endoscopic endonasal approach (EEA) for resection of a GH-secreting pituitary adenoma. Preoperative and postoperative tumor and endocrinological characteristics such as tumor size, invasiveness, and GH/IGF-1 levels were evaluated as potential indicators of postoperative hormonal remission. Endocrinological remission was defined as postoperative IGF-1 levels at or below the age- and sex-normalized values.

RESULTS

The 52 patients had a mean age of 50.7 ± 13.4 years and a mean follow-up duration of 24.4 ± 19.1 months. Ten patients (19%) had microadenomas and 42 (81%) had macroadenomas. Five patients (9.6%) had giant adenomas. Forty-four tumors (85%) had extrasellar extension, with 40 (77%) exhibiting infrasellar invasion, 18 (35%) extending above the sella, and 7 (13%) invading the cavernous sinuses. Thirty-six patients (69%) underwent gross-total resection (GTR; mean maximal tumor diameter 1.47 cm), and 16 (31%) underwent subtotal resection (STR; mean maximal tumor diameter 2.74 cm). Invasive tumors were significantly larger, and Knosp scores were negatively correlated with GTR. Thirty-eight patients (73%) achieved hormonal remission after EEA resection alone, which increased to 87% with adjunctive medical therapy. Ninety percent of patients with microadenomas and 86% of patients with macroadenomas achieved hormonal remission. Preoperative IGF-1 and postoperative day 1 (POD1) GH levels were inversely correlated with hormonal remission. Postoperative CSF leakage occurred in 2 patients (4%), and none experienced vision loss, death, or injury to internal carotid arteries or cranial nerves.

CONCLUSIONS

Endoscopic transsphenoidal resection of GH-secreting pituitary adenomas is a safe and highly effective treatment for achieving hormonal remission and tumor control in up to 87% of patients with acromegaly when combined with postoperative medical therapy. Patients with lower preoperative IGF-1 and POD1 GH levels, with less invasive pituitary adenomas, and who undergo GTR are more likely to achieve postoperative biochemical remission.
Does pituitary compression/empty sella syndrome contribute to MRI-negative Cushing’s disease? A single-institution experience
Authors: Himes Benjamin T. , Bhargav Adip G. , Brown Desmond A. , Kaufmann Timothy J. , Bancos Irina , Van Gompel Jamie J.
Published: June 2020

OBJECTIVE

Cushing’s disease arises from functioning adrenocorticotropic hormone (ACTH)–secreting pituitary adenomas. These tumors can be very small and evade detection by MRI. Empty sella syndrome is a phenomenon by which an arachnoid outpouching of CSF into the sella leads to compression of the pituitary, likely due to intracranial hypertension (a common issue in Cushing’s disease), further leading to difficulty in visualizing the pituitary gland that may contribute to difficulty in finding a tumor on MRI, so-called MRI-negative Cushing’s disease. The authors sought to examine the association between empty sella syndrome and MRI-negative Cushing’s disease.

METHODS

A single-institution database of Cushing’s disease cases from 2000 to 2017 was reviewed, and 197 cases were included in the analysis. One hundred eighty patients had a tissue diagnosis of Cushing’s disease and 17 had remission with surgery, but no definitive tissue diagnosis was obtained. Macroadenomas (tumors > 1 cm) were excluded. The degree of empty sella syndrome was graded on the degree of CSF visualized in the sella on midline sagittal T1-weighted MRI.

RESULTS

Of the 197 cases identified, 40 (20%) presented with MRI-negative disease, and empty sella syndrome was present in 49 cases (25%). MRI-negative disease was found in 18 (37%) of 49 empty sella cases versus 22 (15%) of 148 cases without empty sella syndrome present. Empty sella syndrome was significantly associated with MRI-negative disease (OR 3.32, 95% CI 1.61–6.74, p = 0.0018). Decreased thickness of the pituitary gland was also associated with MRI-negative disease (mean thickness 5.6 vs 6.8 mm, p = 0.0002).

CONCLUSIONS

Empty sella syndrome is associated with an increased rate of MRI-negative Cushing’s disease. Pituitary compression causing a relative reduction in the volume of the pituitary for imaging is a plausible cause for not detecting the tumor mass with MRI.
The Effect of Endorphin Massage towards Decreasing Low Back Pain In Third Trimester Pregnant Women
Authors: Cahyani Ivana Argo , Winarsih Sri , Arfiana Arfiana
Published: June 2020

Background: Pregnancy becomes a meaningful experience with all the changes both physically and psychologically. One of the changes is discomfort that occurs in the third trimester is lower back pain. Lower back pain can cause disruption of daily physical activity. Endorphin massage can be one of the measures to reduce pain in third trimester pregnant women because it releases endorphins from light massage and positive affirmations from the husband.Methods: This research was conducted in the working area of Pare Public Health Center Temanggung District. The methods used Quasi Experimental with Non-Equivalent Control Group Design. The population of this study were all third-trimester pregnant women with a gestational age of 36 weeks, its about 46 people. The tool used the data collection an observation sheet on the scale of Mankoski pain. Data analysis used Wilcoxon test.Result: The results of the study used Wilcoxon test items, namely p value of endorphin massage group of 0,000 with a value of Z 3.787 and the control group p value of 0.025 with a value of Z 2.235. This showed that both groups were equally influential, but the endorphins group had a stronger influence compared to the control group.Conclusion: Endorphin massage had an effect on reduced lower back pain in the third trimester of pregnant women. Endorphin massage contain mild massage and positive affirmations from husband that stimulated the emergence of endorphin so reduce pain sensation roomates. It was expected that endorphin massage can be applied by pregnant women and husband or families as one method of decreasing low back pain because it helped empower husband / families to improve the welfare of pregnant woman.
Heavy cement materials
Authors: Orlovskyi V. M.
Published: June 2020

Emphasis is placed on the urgency of the problem of creating cementitious materials and solutions of high density.

The analysis of scientific sources in the field of development and research of modified cement materials with high density is carried out. The application of different types of weighting impurities to well cements is considered. The advantages and disadvantages of the weighting impurities that are used in the modification of well cements are shown. The technological schemes of the most widespread ways of creation of the weighted cement materials are resulted.

The assortment of weighted cement materials manufactured by the Ukrainian industry is analyzed.

It is noted that improving the quality of the delineation of rocks and oil and gas horizons in exploration areas and industrial fields during the cementing of high-pressure layers and zones with abnormally high reservoir pressures is possible by the development possible  and application of weighted heat-resistant cements with high technological properties on the basis of ash mixtures, as well as mixtures of standard well Portland cement PTSTI-100 and acidic ash removal of thermal power plants and barite weighing agent.

Weighted and heat-resistant grouting materials with high performance properties with the use of industrial anthropogenic products have been developed and investigated.

The selection of optimal recipes of new weighted cement materials was carried out.

The results of the work have practical application in cementing oil and gas wells in complex mining and geological conditions in exploration areas and industrial hydrocarbon deposits.
Soberanía de la persona y solidaridad en la empresa: el caso del cooperativismo
Authors: Morales Gutiérrez Alfonso Carlos
Published: June 2020

.
Reflexiones sobre la evolución del papel del personal operario en la industria
Authors: Alonso Arza Antonio
Published: June 2020

.
Xenofobia y racismo
Authors: Higuera Gonzalo
Published: June 2020

.
Marginación y recursos sociales en Andalucía
Authors: Castón Boyer Pedro
Published: June 2020

.
简析水利建筑工程中的水库大坝除险加固施工安全管理
Authors: 杨 永利
Published: June 2020

现阶段,随着社会的快速发展与进步,国家越来越重视起水利水电工程建设工作。水库作为水利水电工程的重要组成部分,水库加固施工引发了越来越多人的关注。为了更好的保障水库加固施工质量,做好施工管理工作具有重要的现实意义。
电力工程输电线路施工探析
Authors: 曹 贵
Published: June 2020

近几年,我国对电量的需求变得越来越大,为了满足日益增长的电量需求,电力工程项目也在逐渐增多,而输电线路作为整个工程中最重要的环节之一,需要引起电力工程相关人员的重视,提高对输电线路的管理,采用更加先进的施工技术,确保电力工程的施工质量。本文主要研究电力工程中输电线路的应用探析,从输电线路的施工要点和施工技术来进行分析和研究,对目前输电线路在电力工程中存在的问题提出相应的解决对策,希望本文探讨的内容对输电线路的应用和施工具有积极意义。
海外工程成本风险性分析
Authors: 韦 建聚
Published: June 2020

近年来,伴随市场规模逐渐扩大化,我国建筑企业拓展海外市场的步伐明显加快,众多公司在发展国际化的同时也遇到了前所未有的困难和挑战。海外工程成本风险因素越来越多,企业面临的风险也越来越大。本文主要就海外工程成本风险进行分析。
生态理念在水利水电设计过程中的应用探究
Authors: 朱 江
Published: June 2020

随着人们环保意识的不断提升,生态理念逐渐融入到各行各业。水利水电工程作为一项利民工程,我们在保证其经济效益的同时,还要关注其生态效益,将生态理念融入到水利水电工程建设之中,从而保证工程的科学性、生态性和经济性。
试析水利水电建筑工程施工技术应用
Authors: 叶 镇瑜
Published: June 2020

由于社会经济以及科技的不断发展与进步,使得水利水电施工技术进步也很显著,而对于水利水电建筑工程而言,施工技术对其整体施工质量有着直接的影响,另外,在水利水电建筑工程的施工过程中,施工技术具有极大的作用。同样其也作为水利水电工程的一个极为重要的因素,因此,本文对水利水电建筑工程施工技术的应用进行分析。
水利工程项目成本风险AHP评价研究
Authors: 石 辉
Published: June 2020

作为风险管理的基础,风险分析是保障工程项目顺利进行的重要途径。只有针对项目风险进行科学合理的分析,才会制定出行之有效的风险规避措施。结合水利工程项目的特点,评定风险等级,采取合适的风险防范措施,进而达到降低风险的目的。本文以层次分析法来开展水利工程项目成本风险研究工作,通过实际案例分析,提出相关的建议和策略。
浅谈水利工程项目成本管理措施
Authors: 车 光朴
Published: June 2020

水利工程不仅可以实现水资源环境的科学调控和管理,也可为我国国民经济发展及人们生活品质的提高带来保障。不过在水利工程项目建设中,管理问题一直存在,并为项目经济效益带来影响。本文重点对水利工程项目成本管理进行探讨,对存在的问题提出合理解决措施,以改进水利工程建设质量,提升总体经济效益。
浅谈无人值守水利枢纽自动化控制系统
Authors: 赵 韬
Published: June 2020

由于信息化持续发展,在我国水利枢纽的值班工作中也渐渐融入信息化管理,现阶段,在水利枢纽的值班中工作人员已经渐渐的在减少,这样的做法可以将人力资源的使用有效地减少。与此同时,对比人为操作,信息化管理的操作更为精准。为了将水利枢纽自动化管理系统进一步实现,不断发展其有关的技术,所以无人值守理念随之出现。因此,本文分析研究水利枢纽无人值守自动化控制系统的有关设计,以此将水利枢纽无人值守的进程加快进行实现。
分析水利工程造价在设计阶段的控制与管理
Authors: 张 琴凤
Published: June 2020

水利工程与当今社会经济的发展和人们生活水平的提升息息相关。而在水利工程的建设中,工程造价控制又是一项关键内容。众所周知,良好的工程设计可保障工程造价的合理控制。因此,本文就对水利工程设计阶段的造价管理与控制进行分析,以此来为水利工程造价控制提供参考。
Tanque metálico para reservação de água no Brasil: um estudo da aplicação parcial da norma API 650
Authors: Rasi José Roberto , Cauneto Donizete , Broetto Jonathan Figueiredo
Published: June 2020

Com a crescente demanda por reservação de água e pela falta de normas técnicas para reservatórios metálicos no Brasil, vários fabricantes de reservatórios têm utilizado parcialmente a norma API 650 para dimensionamento e verificação desses reservatórios. Neste trabalho, foram realizados estudos para a verificação da aplicação parcial e integral da norma API 650, método 1 pé, através de dimensionamento de 7 tanques metálicos com o mesmo volume em função de diferentes relações altura/diâmetro (H/D). Analisa – se as tensões circunferenciais nos dois casos e dimensionamento previsto na API 650 e determina as relações altura/diâmetro mais econômicas para o armazenamento de água.
NEEDS ANALYSIS FOR ENGLISH TEACHING/ CURRICULUM DEVELOPMENT IN INDONESIAN SENIOR HIGH SCHOOLS
Authors: Hutauruk Risuli
Published: June 2020

Although Indonesian students have learnt English for 6 years when they graduate, there are still many of them who cannot speak the foreign language. One of the important factors which must be taken care of is the syllabus or curriculum of teaching English. The syllabus should be prepared in such a way so that it can match the needs of the students and, in the end, can function well to make students able to speak English when they graduate. A small research has been made to find the target situation analysis, objective needs analysis, subjective needs analysis and present situation analysis (Dudley-Evan & St. John, 1998). The respondents of the research are students from private and government senior high schools. All the respondents belong to Gen Z, who are used to using digital tools and the internet in their daily life. The results show that Gen Z prefers to use digital tools in learning English at school. This study is expected to propose a syllabus design which deploys technology or digital tools in teaching.
Leading air pollution related reasons of death
Authors: Saltykova Marina M. , Balakaeva A. V. , Fedichkina T. P. , Bobrovnitskii I. P.
Published: June 2020

The aim of this study was to analyze the effect of air pollution on the structure of reasons of death from major non communicable diseases in cities of the Russian Federation Material and methods. The study analyzed the mortality of people of working age (with stratification by gender and causes of death) in pairs of cities, with matching the cities of each pair by the climatic and socio-economic conditions, but the level of air pollution in one city significantly exceeded the level of pollution in another. The following pairs of cities were formed (“dirty” - “relatively clean”): Bratsk-Kirov; Nizhny Tagil-Kirov; Novokuznetsk-Tomsk; Chita-Tomsk; Magnitogorsk - Orenburg, Cherepovets-Vologda. The analysis included data on the mortality from diseases of the circulatory system, respiratory system, and oncological diseases, since according to WHO, air pollution primarily affects mortality from coronary heart disease, stroke, chronic obstructive pulmonary disease, and lung cancer. Results. The mortality rate of people of working age from diseases of the circulatory system, primarily from cardiovascular diseases, is significantly higher in cities with a high level of pollution compared with cities with a lower level of pollution and similar climatic and socio-economic conditions. The mortality rate of men from cerebrovascular diseases in the group of dirty cities is higher than in compared cities in 4 out of 6 studied pairs. Moreover, differences in the mortality rate in women were less pronounced, they were revealed in 2 out of 6 compared pairs. The differences in mortality from oncological diseases were detected in 4 out of 6 comparison pairs for women and 2 out of 6 compared pairs for men. Conclusion. An analysis of the mortality used pairwise comparison of cities showed air pollution to most affect on the mortality from diseases of the circulatory system.