bluuebunny/crossref_metadata_2025 huggingface dataset:
Russian-Ukraine 2022 War: A Review of the Economic Impact of Russian-Ukraine Crisis on the USA, UK, Canada, and Europe
Authors: Mbah Ruth Endam , Wasum Divine
Published: March 2022

The popular belief worldwide is that the global financial sanctions unleashed on Russia, the seizure of assets and properties of the oligarch friends to President Putin for Russia’s current attack on Ukraine will cripple the Russian economy and hinder any further attack on Ukraine. This is logical reasoning, however, the impact of this crisis extends to the global economy. Thus, the purpose of this study is to review the economic impact of the 2022 Russia-Ukraine war on key global economic actors, specifically, countries that have unleashed financial sanctions on Russia as punishment like the USA, Canada, UK, and EU. This study uses the Social Contract and the Interest Group Theories to explain the rationale behind this crisis from its origin. Evidence from reviewed literature shows that although the consequences of this crisis have had a fatal impact on Russia’s economy, the world economy has begun to feel the impact of this crisis. Inflation which is already ravaging most global economies is steadily rising due to the sharp increase in oil, natural gas, and food prices just a few days into this crisis. Experts expect a negative impact on household consumption, increase uncertainty, unpredictable stock swings, supply chain disruptions, bulging utility bills, decreased investment due to political risks, and economic growth impediments.  It is therefore vital for policymakers worldwide to seek alternative means of survival if Russia decides to react by restricting its export of vital global commodities of which it is a significant export leader like oil, natural gas, wheat, neon, titanium, palladium, and ammonium nitrate.
Comparison of VIS/NIR spectral curves plus RGB images with hyperspectral images for the identification of Pterocarpus species
Authors: Wang Cheng-Kun , Zhao Peng , Li Zhen-Yu , Li Xiang-Hua
Published: March 2022

The image information and spectral information of wood sections can be used to identify wood species. Hyperspectral images have both image information and spectral information, but they have disadvantages such as large data capacity, slow reading speed, and the necessity of expensive equipment for their acquisition. In this study, the classification results of Pterocarpus by using visible/near infrared (VIS/NIR) spectral information and RGB images were compared with hyperspectral images. The VIS/NIR spectral curves, Hyperspectral, and RGB images of five wood species of Pterocarpus with similar transverse-sections were collected. In feature-level fusion, the feature vectors are directly connected in series, and features fused by canonical correlation analysis are compared. In decision-level fusion, an extreme learning machine and a composite-kernel support vector machine (SVM) are used and compared. In the feature- and decision-level fusion methods, the recognition results of VIS/NIR spectral curves plus RGB images were largely similar to those of hyperspectral images. Therefore, a recognition effect similar to that of the hyperspectral image can be obtained by collecting the spectral information and image information of wood sections separately, which can reduce the cost of data acquisition and improve the speed of data processing.
On the excitation and radiative decay rates of plasmonic nanoantennas
Authors: Bedingfield Kalun , Demetriadou Angela
Published: March 2022

Plasmonic nanoantennas have the ability to confine and enhance incident electromagnetic fields into very sub-wavelength volumes, while at the same time efficiently radiating energy to the far-field. These properties have allowed plasmonic nanoantennas to be extensively used for exciting quantum emitters—such as molecules and quantum dots—and also for the extraction of photons from them for measurements in the far-field. Due to electromagnetic reciprocity, it is expected that plasmonic nanoantennas radiate energy as efficiently as an external source can couple energy to them. In this paper, we adopt a multipole expansion (Mie theory) and numerical simulations to show that although reciprocity holds, certain plasmonic antennas radiate energy much more efficiently than one can couple energy into them. This work paves the way towards designing plasmonic antennas with specific properties for applications where the near-to-far-field relationship is of high significance, such as: surface-enhanced Raman spectroscopy, strong coupling at room temperature, and the engineering of quantum states in nanoplasmonic devices.
Numerical and experimental investigations of tip clearance effects in a high-flow-coefficient centrifugal compressor
Authors: Zhao Chenxi , Yang Changling , Zhang Chenqing , Zhang Xiaotian , Xi Guang
Published: March 2022

This paper focuses on the investigation of the blade deformation and tip clearance effects of a high-flow-coefficient centrifugal compressor. Blade deformation caused by the pressure load and centrifugal load under operating condition is considered by fluid/solid interaction method to simulate the stage performance accurately. Hence the numerical results are in good agreement with the experimental data. The blade deformation is then analyzed in detail. Also, the effect of the size of tip clearance is studied by evaluating the performance with five various gaps. The result shows that the increment of the tip clearance from 0 to 2.0 mm leads to a 5.14% peak efficiency decline. However, increasing tip gap contributes to enlarge the stable operating range in terms of stall margin and choke margin.
FACTORS HINDERING THE CONDUCT OF AUDITS OF CORPORATE SOCIAL RESPONSIBILITY REPORTS: EVIDENCE FROM POLAND
Authors: Bartoszewicz Anna , Rutkowska-Ziarko Anna
Published: March 2022

This article presents the results of empirical research conducted among audit firms in Poland regarding the factors hindering the provision of non-financial information verification and attestation services. The rapidly developing practice of non-financial reporting among socially responsible entities in Poland does not translate into the number of reports that are subjected to external audits. Despite the unquestionable need to confirm the reliability of non-financial data, services of this type are not provided by the majority of audit firms. The primary aim of the article is to identify the factors hindering the performance of audits of non-financial reports in Poland. The article identifies the entities operating in the Polish audit market in terms of selected features. The authors provided answers to three main research questions: What percentage of audit firms in Poland carry out the verification of non-financial reports? What is the size and the level of employment of audit firms in Poland? What factors hinder, in the auditors’ practice, the performance of audits of non- financial reports? To achieve the objective, a survey research was conducted among audit firms under the supervision of the Polish Agency of Audit Oversight. The theoretical basis of the article included a literature study on the audit of non-financial reports as well as an analysis of regulations governing this subject matter in Poland. This study is the first such review of factors that condition the use of such an important tool as an audit in non-financial reporting. The obtained study results indicate that only 2.3% of audit firms perform audits of CSR reports. The main factor that limits audit firms in the performance of this type of services is the low demand in this regard. Moreover, the audits of non-financial reports are limited by insufficient staff.
Slow Progress for Women with Disabilities in India
Authors: Addlakha Renu
Published: March 2022

This essay examines the engendering of disability in India over the past half a century through a reflexive lens; the author has been both an observer and participant in this process. The article looks at how women with disabilities have emerged as a distinct category in the different registers of state, civil society, and academia, in the face of overwhelming odds as individuals and invisibility as a group. It also discusses how notions of human rights and empowerment play out in the entangled web of state discourses, routine practices, and everyday lived experiences.
Python Inspired Smart Braking System to Improve Active Safety for Electric Vehicles
Authors: Patil Lalit , Khairnar Hrishikesh
Published: March 2022

In today’s world, electric cars are gaining popularity as a mode of transportation due to their smooth and comfortable rides. Since electric cars/bikes do not emit exhaust emissions, environmental standards will improve; however, an unintended upcoming risk of accidents has been identified due to the quiet nature of electric vehicles. The increasing trend of road accidents is resulting in serious injuries or even severe disability. In view of this, it was intended to develop the smart control system by using neural network techniques to enhance safety, especially for electric vehicles. The obstacle detection and smart control strategy were achieved by employing a state flow network. Furthermore, The driver’s behavior was monitored with the aid of a web camera. If the drowsiness/fatigue state of the driver is being detected by the system, then immediate precautionary steps would be carried out such as warning indicators, emergency braking, and stop. To execute this method, the number of input processing hardware devices and software algorithms were used collaboratively. The prototype has been developed to conduct the necessary trials for vindication. The findings show that the control strategy of the proposed model was successfully incorporated on the test bed with consistent results concerning control in numerous situations. The proposed smart braking system would be beneficial to both road users and passengers for improving safety.
El rincón de Roberto Gottardi
Authors: Paradiso Michele , Altemura Marco , Garuglieri Sara
Published: March 2022

Dopo la vittoria dei rivoluzionari sul governo filoamericano di Fulgencio Batista, l’isola di Cuba visse un momento di rinascita e forte positività. Il piano di socializzazione castrista coinvolse numerose figure professionali straniere. Tra questi, all’inizio del 1960 prese parte l’architetto veneziano Roberto Gottardi partecipando all’immensa impresa della realizzazione delle Scuole d’Arte a L’Avana tramontata prematuramente. Il suo lavoro, la sua ricerca in materia di disegno, sono state riconosciute nel 2016 con il Premio Nacional de Arquitectura dell'associazione Union de Arquitectos e Ingenieros de la Construcción di Cuba. Questo studio inizialmente ripercorre le tappe fondamentali della vita di Roberto Gottardi, dagli studi allo IUAV fino al suo arrivo a Cuba e ne delinea la figura professionale. L’eredità culturale che Gottardi lascia al suo paese adottivo prende infine collocazione all’interno di un nuovo spazio, frutto di questa ricerca, chiamato “El rincón de Roberto Gottardi”, una biblioteca - museo in sua memoria inserito all’interno della Scuola che lo ha reso internazionalmente celebre e sulla quale ha lavorato fino agli ultimi giorni di vita.
TEMPO-media oxidation combined with laccase for effective degumming pretreatment of hemp fibers
Authors: Liu Liu , Xiang Yeping , Zhang Ruiyun , Li Bei , Yu Jianyong , Fang Bin
Published: March 2022

TEMPO-media oxidation and laccase have been successfully used in fiber degumming, but the combination of the two methods in the hemp degumming process has not yet been reported. In this paper, an alternative and efficient way for the pretreatment of hemp degumming was proposed as a combination of TEMPO-media oxidation with laccase and was a TEMPO-laccase system. A chemical composition analysis, Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), and scanning electron microscopy (SEM) were applied to systematically analyze and compare the degumming efficiency between the TEMPO-laccase system and other pretreatments. The results showed that after the TEMPO-laccase system degumming process, a clean and smooth surface of the degummed fibers could be observed and the non-cellulosic materials were greatly removed without any crystalline transformation. The hemp fibers after the TEMPO-laccase system degumming process had the most desirable linear density of 6.64 dtex and a tenacity value of 3.41 cN/dtex. This new pretreatment had a considerable effect on hemp degumming, which holds promise for use of high-value textiles.
Hora Zero del Centro: poetas y el “poema integral” en Huancayo, 1978-1983
Authors: Salazar Solano Roberto
Published: March 2022

Este artículo se centra en la fundación de Hora Zero del Centro en la provincia de Huancayo (Perú), durante finales de los años setenta, matizado por el diverso hecho social que se imprimió en la múltiple discursividad local; exponiendo en objetivo la caracterización de hechos, poetas en Huancayo que militaron en la segunda etapa de Hora Zero (1977) y modo de ejercitar los postulados estéticos del “poema integral”. Para comprender las nociones de participación y agenciamiento se realiza análisis histórico-literario de los documentos de esos puntos de enunciación: Hora Zero del Centro, Primer manifiesto, Recital 1(1978), y Hora Zero Huancayo (1983).
La habitación como revelación de espacio sagrado (Axis mundi) en Habitación en Roma de Jorge Eduardo Eielson
Authors: Dámaso Tamayo Kristel Aylin
Published: March 2022

El presente trabajo de investigación tiene como objetivo analizar la representación de la habitación en el libro de Jorge Eduardo Eielson Habitación en Roma, específicamente, en el poema “foro romano”. Nuestra hipótesis afirma que dicho lugar se evidencia como un espacio sagrado (Axis mundi). Además, dicha revelación surge como imagen poética en la consciencia del yo poético a través del ensueño, el cual permite acercarse a su pasado en el inconsciente primitivo, es decir, a su homo religiosus. Nuestro marco teórico es la fenomenología de la historia de las religiones de Mircea Eliade y la del espacio de Gastón Bachelard. Finalmente, nuestra herramienta de análisis es la hermenéutica.
Uniqueness of the solution of one class of Volterra-Stieltjes linear integral equations of the third kind
Authors: Asanov Avyt , Matanova Kalyskan , Absamat kyzy Eliza
Published: March 2022

In this paper, the question of uniqueness of the solution for one class of Volterra-Stieltjes linear integral equations of the third kind is investigated. The notion of derivative with respect to an increasing function was introduced by A. Asanov in 2001 and plays special role in the study. This notion is a generalization of the usual concept of a derivative function and is an inverse operator for one class of the Stieltjes integral. Basing on idea of such derivative, using the method of integral transformations and the method of non-negative quadratic forms, the uniqueness theorems for the solution of the considered class of integral equations are proved. Examples satisfying the conditions of uniqueness theorems are also constructed in the paper. It becomes clear from these examples that it is difficult to study Volterra-Stieltjes linear integral equations of the first and third kind without using the notion of derivative with respect to increasing function.
LINTASAN BELAJAR MATERI ARITMATIKA SOSIAL DENGAN PENDEKATAN PENDIDIKAN MATEMATIKA REALISTIK DI SMP NEGERI 1 BATANG ANGKOLA KABUPATEN TAPANULI SELATAN
Authors: Annisa Putri , Rangkuti Ahmad Nizar
Published: March 2022

The Purpose of the research is to find out validation and practically learning trajectory by realistic mathematics education approach of social arithmetic object in SMP Negeri 1 Batang Angkola. This research in research forming design research type validation study even the purposing developing local intruction theory (LIT) by compinion researcher and teacher to improving quality of learning. The action this research at SMP Negeri 1 Batang Angkola by experience subject of product in grade VII-A, leader 32 students. The instrument collecting data by using validation paper, questionnaire and using analysing validation technique and practicalitation. The result of research point out learning trajectory by realistic mathematics education approach said valid and practice. The validating source learning point out with score 76% by analyses 2 validator. The practicitation source learning find out with score 88% from questionnening respon of students, action all componens. Realistic Mathematics Education Approach to proccesing learning and extracted student in learning social arithmetic material. The source of learning resulting to this research forming activities action from reaching the purpose of learning, when purpose of learning are understanding social arithmetic concept.
MENINGKATKAN PEMAHAMAN PESERTA DIDIK MELALUI PEMBELAJARAN REMEDIAL METODE TUTOR SEBAYA PADA MATA PELAJARAN MATEMATIKA DI KELAS XII MIA 3 MAN 2 TANAH DATAR TAHUN PELAJARAN 2018/2019
Authors: Diana Pesma , Fitriza Rozi
Published: March 2022

This research is focusing on the efford to enhance students’s understanding, especially for those who have not complete the minimum mark attainment, through peer teaching remedial learning  at 12th Natural Science 3 class, academic year 2018/2019. This is an action class research. Data in this research are qualitative dan quantitative. Qualitative data were gained throughobservation towards students’s activities during peer theaching remedial learning process and through interview. While quantitative data were gathered from daily score and from the test after treatment finishing. The result of the research showed that there is an improvement of students’s understanding through the peer teaching activity. It is showed by the higher percentage of students’s who could reach the minimum score attainment in one basic competence, and it was revealed that students were more active and enthusiastic to ask questions and explanations to their while the remedial teaching took place.
PENGARUH MODEL PEMBELAJARAN JUCAMA TERHADAP KEMAMPUAN PEMECAHAN MASALAH SISWA KELAS IX MTSN 02 TAKENGON
Authors: Umar Ali
Published: March 2022

This study supports 1). Knowing the differences in problem-solving abilities in students before and after being taught with the JUCAMA learning model; 2). Knowing students' problem solving skills between before and after being taught with the JUCAMA learning model in high initial students; 3). Knowing students' problem solving skills between before and after being taught with the JUCAMA learning model in students with low initial ability; 4). Conversation between initial ability and learning model on students' problem solving. This study uses quantitative research with a quasi-experimental type of research. The results showed 1). 95% (16.67> 9.98, tcount = 7.816> t table = 1.71; 2). The average problem solving ability of students in early ability students was higher after being taught with the JUCAMA learning model than before at 95% confidence level (16.09> 13.72, tcount = 15.53> ttable = 1.81); 3. The average problem solving ability of students in early ability students is lower after being taught with the JUCAMA learning model than before at 95% confidence level (10.31> 7.25, tcount = 5.21> ttable = 1.75). While the results of the interaction test showed there was no interaction between the initial ability and the learning model on the ability to solve students' problems at a 95% confidence level (Fcount = 0.29 <Ftable = 1.35), so that the JUCAMA learning model was suitable for use with diverse abilities . Based on the research it was also found that students needed more time than usual to solve problems of type solving problems.
KEPEMIMPINAN VISIONER DALAM MENINGKATKAN MUTU PENDIDIKAN DI UNIVERSITAS ISLAM NEGERI IMAM BONJOL PADANG
Authors: - Bustari
Published: March 2022

This study aims to determine 1) Policies taken by the leaders of Imam Bonjol Padang Islamic State University (UIN IB) in achieving the vision, mission and goals of the campus; and 2) Leaders' efforts in realizing visionary leadership for the advancement of UIN IB Padang. This research uses field research methods with qualitative descriptive analysis techniques. The collected data is then analyzed using the inductive approach. The results of this study indicate 1) The leadership of UIN IB Padang has conceptualized the campus vision to be more focused, focused, and oriented towards future challenges. In addition, in completing every program the leadership of UIN IB always has principles on the 4 principles of UIN IB values, which are: faithful, knowledgeable, moral and cultured; 2) The Chancellor of UIN IB Padang always fosters good relations between lecturers, employees and students, as well as to stakeholders. Furthermore, the Chancellor of UIN IB provides support so that all components of tertiary institutions can optimally improve performance, and always support the creativity of students, lecturers and employees. In addition, the Chancellor of UIN IB Padang always provides information to all campus leadership units to become a superior campus in Islamic scholarship in ASEAN in 2037. From some of the findings above, it can be concluded that the visionary leadership at UIN IB Padang has been optimally implemented.
PENGARUH GAYA KEPEMIMPINAN KEPALA SEKOLAH TERHADAP EFEKTIVITAS SEKOLAH PADA SEKOLAH MENENGAH KEJURUAN NEGERI DI PROVINSI JAMBI
Authors: Istikomah Istikomah
Published: March 2022

Principal's leadership is one of the supports success of a school to be an effective school. Being an effective school there needs to be a strong headmaster's leadership because the meaning of leadership is one's attitude to be able to influence others in order to work according to their responsibilities and achieve desired goals. This research is quantitative research with a survey method. From the results of this study, it was found that the principal's leadership style significantly influenced the effectiveness of schools in the State Vocational High School in Jambi Province. Based on the results of the analysis, the obtained value of thitung (8,54) > ttabel (1,969),  H0 is rejected and H1 is accepted. This means that the high leadership style of the principal has a significant influence on school effectiveness. This means that the extent effectiveness of application the principal's leadership style will result, increase in school effectiveness. The research implications of these findings explain that better the principal's leadership style, more influential school's effectiveness will be.
ANALISIS PRODUKTIVITAS MAHASISWA INSTITUT AGAMA ISLAM (IAI) NUSANTARA BATANGHARI MELALUI PEMBELAJARAN ONLINE
Authors: Yusup Muhammad , Marzani Marzani
Published: March 2022

This paper is motivated by the conditions of learning during the Covid-19 pandemic. The learning process must be done from home. In accordance with government policy, work from home and learn from home. The purpose of this research is to study the creativity of students in implementing online learning during the Covid-19 pandemic. The research method used is using a qualitative method with descriptive analysis. And as respondents and sources of data for this study were students of IAI Nusantara Batanghari. The results showed as many as 79.4% thought online learning was very effective, while 20.6% thought it was not yet effective. That means effectiveness can increase student productivity. This result is supported by data as much as 23% they strongly agree, 44% agree, and there are 15% of students who disagree. It shows the quality of online learning, increases student productivity, both increases productivity in soft skill development and self-development increases business efficiency in meeting daily needs.
PENERAPAN MANAJEMEN PEMBELAJARAN DI SEKOLAH DASAR SELAMA PANDEMI
Authors: Umi Rahmawati Dwi Nur , Puspita Ratna Dewi
Published: March 2022

This study aims to reveal how far learning management is carried out by teachers in schools and how learning management is implemented by teachers during the pandemic. This research is Mixed Method research with a sequential explanation method. Samples were taken using a purposive sampling technique. Data collection techniques used questionnaires and data analysis using statistics as an analysis technique followed by interviews and documentation then validated the findings with the Member Checking strategy. The results of statistical analysis of the implementation of learning management based on the function of learning management which includes planning, organizing, mobilizing, and monitoring during the pandemic are categorized as "Medium". This means that the implementation of learning management has not been fully implemented, there are indicators that cannot be met by the teacher in the driving / implementation function. Application of learning management which includes functions; planning, organizing, mobilizing, and supervising teachers according to pandemic conditions. The learning planning function is carried out by preparing learning instruments including syllabus and lesson plans which are prepared by paying attention to distance learning policies; the implementation of the organizing function is carried out with the teacher in coordination with the preparation and implementation of learning with parents; the learning implementing function is carried out with blended learning, the learning evaluation function is carried out through written, oral and practical evaluations that utilize applications on smartphones.
Insights into Interaction of CO\(_2\) with N and B-doped Graphenes
Authors: Xuan Huynh Nguyen Thi , Chihaia Viorel , Son Do Ngoc
Published: March 2022

Graphene is a promising candidate for CO2 capture and storage. Doping graphene with other elements is an effective way to modify its CO2 storage ability. The literature has shown that the N and B doping could change the adsorption strength of CO2 on the graphene substrate. However, there is no research available to elucidate the adsorption sites and the physical properties underlying the interaction of CO2 with the N and B doped systems. Therefore, this paper is devoted to clarifying the current topic using the self-consistent van der Waals density functional theory calculations. The results showed that the N and B doping increases and decreases the adsorption energy of CO2, respectively. The reason is that there are more peaks of the electronic density of states of CO2 participating in the interaction with the N p orbital than with the B p orbital.
Confirmed Detection of Lithium in Nearby Young Late-M Dwarfs
Authors: Ngoc Phan Bao , Bessell Michael S.
Published: March 2022

Brown dwarfs in nearby young associations and moving groups are excellent benchmarks for studyingphysical properties of these substellar objects at different ages as well as their formation mechanism.In our previous search for nearby young brown dwarfs, we reported the first clear detection of the lithium absorption line in three late-M dwarfs and a marginal detection in one late-M dwarf.Based on our new spectroscopic observations, we confirm our previous detection of lithium inthe four late-M dwarfs. We also confirm the presence of lithium in one brown dwarf binary that haspreviously been reported in the literature. Using theoretical models, we estimate the age and the mass of these late-M dwarfs. We then use a Bayesian analysis tool for determining the membership probability of these young late-M dwarfs to nearby young moving groups.
Gauge Origin of Double Dark Parity and Implication for Dark Matter
Authors: Phung Dong Van , Duong Van Loi
Published: March 2022

Dark matter must be stabilized over the cosmological timescale, which demands the existence of a stabilizing symmetry, derived by a dark charge, $D$. The existence of this dark charge may affect the quantization of electric charge, which theoretically shifts the electric charge, thus the hypercharge to a novel gauge extension, $SU(3)_C\otimes SU(2)_L\otimes U(1)_Y\otimes U(1)_N$, where $N$ determines $D=T_3+N$, similar to $Q=T_3+Y$. New observation of this work is that the dark charge is broken down to two kinds of dark parity, $Z_2$ and $Z'_2$, which subsequently imply three scenarios of dark matter. The relic density and direct detection for the scenario of two-component dark matter are investigated in detail.
Safety, pharmacokinetics and pharmacodynamics of an original glycoprotein IIb/IIIa inhibitor in healthy volunteers: results of the clinical trial
Authors: Fitilev S. B. , Glukhov Yu. F. , Lukyanov S. V. , Vozzhaev A. V. , Shkrebniova I. I. , Kazey V. I. , Bondareva I. B.
Published: March 2022

Aim. To study the tolerability, safety, pharmacokinetics (PK) and pharmacodynamics of single intravenous infusions of Angipur in healthy male volunteers.

Material and methods. The Phase I trial included 20 healthy male volunteers (mean age, 30,8±7,7 years; mean body weight, 77,4±12,1 kg). Angipur (0,02% concentrate for solution for infusion) was administered to every subject in single doses 0,015, 0,05, 0,09 mg/kg for 3 consecutive days. Volunteers were divided in 6 groups (1, 1, 3, 5, 5, 5); every following group was recruited only after the previous one finished the study. The following were assessed: rate and severity of adverse events (AEs), key PK parameters of Angipur and its antiplatelet activity by impedance aggregometry.

Results. No moderate or severe AEs, as well as no serious AEs were reported according to obtained data of clinical and laboratory monitoring of healthy subjects. Totally 6 mild AEs were registered in 4 subjects. Four AEs (mild hematological deviations and episode of nose bleed) were classified as possibly related to study drug and 1 AE (positive fecal occult blood test)  — probably related. Key PK parameters of Angipur in single intravenous doses 0,015, 0,05 и  0,09 mg/kg were determined as follows: Cmax — 12,44±4,689, 46,10±14,295, 92,48±33,896 ng/ml; Vd  — 304,01±55,300, 299,67±64,244, 252,96±47,790 l; T1/2  — 6,72±1,290, 6,84±2,341, 6,06±2,287 h; Cl  — 32,19±6,919, 32,29±8,357, 31,55±10,113 l/h, respectively. Dose proportionality (linear PK) for parameters Cmax, AUC0-t and AUC0-∞ was established. Dose-dependent reduction of ADP-induced platelet aggregation degree and area under curve was revealed at period of 15 min to 2-4 h after Angipur infusion in doses 0,05 and 0,09 mg/kg.

Conclusion. Results of phase I clinical trial demonstrated good tolerability of single intravenous infusions of Angipur (0,015, 0,05 и 0,09 mg/kg) in healthy subjects. We determined key PK parameters and indicated dose-dependent antiplatelet activity of Angipur.
Correlation between markers of fibrosis and myocardial remodeling in patients with various course of hypertrophic cardiomyopathy
Authors: Bogatyreva F. M. , Kaplunova V. Yu. , Kozhevnikova M. V. , Shakaryants G. A. , Privalova E. V. , Belenkov Yu. N.
Published: March 2022

Aim. To assess the relationship between fibrosis markers and structural and functional parameters in patients with various types of hypertrophic cardiomyopathy (HCM).

Material and methods. This prospective comparative non-randomized study included 49 patients with HCM. Patients were divided into 3 groups according to the disease course: group 1  — stable course (n=12; men, 8 (67%), mean age ‒ 41±12 years); group 2 — progressive course (n=26; men, men, 16 (61%). mean age — 57±11 years); group 3 — patients with atrial fibrillation (AF) (n=11; men, 4 (36%), mean age — 63±6 years). Patients underwent standard clinical and paraclinical investigations. The levels of matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of metalloproteinases-1 (TIMP-1) were determined in all patients using enzyme-linked immunosorbent assay in blood serum.

Results. In all patients with HCM, elevated levels of MMP-9 and TIMP-1 are noted compared to the reference values. In group 1, the MMP-9 level [Me (Q1; Q3)] was 226 (201;271) ng/ml; TIMP-1 — 410 (267;488) ng/ml; in group 2, the MMP-9 level was 236 (187;285) ng/ml; TIMP-1 — 421 (321;499) ng/ml. In the course with AF, the MMP-9 level was 260 (228;296) ng/ml, while TIMP-1 — 381,5 (305;466) ng/ml; no significant difference was revealed (p=0,59; p=0,90, respectively). A correlation was found between age and MMP-9 levels, as well as between MMP-9 levels and left atrial volume (p=0,034; p=0,035, respectively).

Conclusion. The high activity of matrix metalloproteinases and their tissue inhibitors reflects enhanced fibrosis and myocardial remodeling in HCM, which is especially characteristic of patients with AF.
Factors associated with awareness and passage of medical screening in hypertensive persons: data from the Know Your Heart study
Authors: Kashutina M. I. , Kontsevaya A. V. , Kudryavtsev A. V. , Malyutina S. K. , Ipatov P. V. , Drapkina O. M.
Published: March 2022

Aim. To analyze the demographic, socio-economic and behavioral factors associated with awareness and passage of medical screening among the hypertension adults from Arkhangelsk and Novosibirsk.

Material and methods. The database was formed as part of the Know Your Heart study (2015-2018, Arkhangelsk, Novosibirsk, n=4504). For the present study, 2216 people with hypertension were selected. Binary logistic regression was used to determine the factors associated with awareness of ongoing medical screening and active participation in them.

Results. The analysis determined that 82,5% of the hypertensive residents of Arkhangelsk and Novosibirsk aged 35-69 years old are aware of the medical screening, and 51,4% have passed (are going to pass) it. General factors associated both with greater awareness of ongoing preventive measures and with greater participation in them are female sex and contacts with doctors during the year. From the point of view of awareness, such a factor as the average income level turned out to be significant, while the absence of a permanent employment and the pension status were associated with the passage of medical screening.

Conclusion. The awareness of the hypertensive residents of Arkhangelsk and Novosibirsk about the medical screening was 82,5%. The coverage level is still low. The identified factors associated with greater awareness of the medical screening and more active participation showed that medical specialists should be more attentive to the men working in urban areas with a low income level. More active work is also needed to involve in preventive contacts those persons who are not in constant contact with the healthcare system. This requires the consolidated work of various institutions and departments, including the media.
Levels of angiogenesis markers in patients with different heart failure phenotypes
Authors: Shepel R. N. , Drapkina O. M.
Published: March 2022

Aim. To assess the relationship between the levels of angiogenesis markers and various heart failure (HF) phenotypes in patients with class II-IV HF of ischemic origin.

Material and methods. This cross-sectional cohort study was based on the clinical departments of the National Medical Research Center for Therapy and Preventive Medicine. The study involved 180 patients aged 30-85 years with class II-IV HF of ischemic origin as follows with (n=90) and without (n=90) metabolic syndrome (MS). All patients included in the study signed an informed consent to personal data processing, participation in a clinical trial and consent to blood biobanking. All patients were divided into three groups: HF with reduced ejection fraction (HFrEF)  — left ventricular (LV) EF <40%, HF with mildly reduced EF (HFmrEF) — LVEF from 40 to 49%, HF with preserved EF (HFpEF)  — LVEF >49%. In addition to the standard paraclinical investigations, angiogenesis markers were analyzed with the determination of transforming growth factor β (TGF-β), vascular endothelial growth factor A (VEGF-A), pentraxin-3 (PTX-3). Statistical analysis was performed using Microsoft Office Excel, STATISTICA 10.0 software packages (Statsoft, USA).

Results. Transthoracic echocardiography determined that 74 (41,1%) patients had LVEF <50%, while 71 (39,4%)  — <40%. For the group of patients with HFpEF, there was an association with an increase in TGF-β ≥7,2 ng/ml (p=0,011). The threshold level of PTX-3 ≥55 ng/ml is associated with the development of HFpEF (p=0,001). For the HFmrEF phenotype, the threshold values of VEGF-A, TGF-β and PTX-3 were determined, which did not reach the significance level. However, an upward trend in VEGF-A >200 ng/ml was noted (p=0,052). In HFrEF patients, a threshold value of VEGF-A >195 ng/ml (p=0,001) associated with reduced LVEF was determined.

Conclusion. Thus, the present work showed the relevance of using PTX-3, VEGF-A and TGF-β as additional markers for assessing the HF course. So, patients with HFpEF had increased levels of PTX-3 and TGF-β, while patients with HFmrEF and HFrEF  — increased VEGF-A values. Determination of the level of these angiogenesis markers should be used to improve the efficiency of diagnosis and treatment of patients with various class II-IV HF phenotypes.
Empirical Evaluation of Machine Learning Classification Algorithms for Detecting COVID19 Fake News
Authors: Alsaidi Hiba , Etaiwi Wael
Published: March 2022

Abstract Humans have been fighting the Covid19 pandemic since it started, not just to protect their wellbeing but also to counteract the news and rumors that have been spreading about it. Rumors and false allegations can be almost as dangerous as the virus, as they affect people's mental health and increase their stress levels. To address this problem, several machine learning techniques could be used to detect fake news. In this paper, four different machine learning algorithms are compared according to their ability to detect fake news, including Naive Bayes, Decision Tree, Support Vector Machines, and Logistic Regression. A dataset of annotated news is used in the experiments. The experimental results show that Naïve Bayes outperforms other algorithms in terms of accuracy, precision, recall, and F1 score. Keywords: COVID-19, Machine Learning, Fake news detection.
Conservation of the Black-collared Swallow, Pygochelidon melanoleuca (Wied, 1820) (Aves: Hirundinidae) in Brazil: potential negative impacts of hydropower plants
Authors: Silva Gabriele Andreia da , Frederico Renata Guimarães , Almeida Sara Miranda , Salvador Gilberto Nepomuceno , Malacco Gustavo Bernardino , Melo Celine de
Published: March 2022

Abstract: We analyzed the overlap of the range of Pygochelidon melanoleuca in Brazil with active and planned hydropower plants in the country (current and future scenarios). We used the Random Forest, Maxent and Support Vector Machine algorithms to model the potential range of the species, which we then overlapped with the locations of active and planned hydropower plants in order to calculate how much the potential area of this species is and will be affected by them. Approximately 35% of active hydropower plants currently overlap with the potential distribution area of P. melanoleuca, and 44% of planned hydropower plants also coincide with this area. If the implementation of the planned hydropower plants occurs, the suitable habitat necessary for nesting and foraging of P. melanoleuca will be severely compromised.
Contributions to the future of metaheuristics in the contours of scientific development
Authors: Sampaio Nilo Antonio de Souza , Reis José Salvador da Motta , Espuny Maximilian , Cardoso Ronald Paland , Gomes Fabricio Maciel , Pereira Felix Monteiro , Ferreira Luís César , Barbosa Motta , Santos Gilberto , Silva Messias Borges
Published: March 2022

Abstract Metaheuristic algorithms solve optimisation problems by identifying the best combination among a set of variables to enhance a function. Within metaheuristics, the main purpose of this work is that of showing the development of research issues about processes related to optimisation and metaheuristics, with a focus on the projection of those issues with greater possibility of development. Optimization processes is one of the most studied fields in artificial intelligence, optimization, logistics, and other applications The main contributions of this work were the identification of the main issues contained in the themes of process optimization and metaheuristics; an analysis of the expansion and retraction of the aforementioned theme; an understanding of convergence and divergence; and an analysis of the stages of development as presented in the gaps of the fifty most commonly mentioned articles. The main finding was to analyze the development of research topics on optimization processes and metaheuristics, focusing on projecting the topics most likely to develop.
ENQUADRO E BANCO DOS RÉUS: RACISMO E SISTEMA DE JUSTIÇA
Authors: Alves Júlia Somberg , Moreira Lisandra Espíndula
Published: March 2022

Resumo A partir de reflexões que analisam o racismo como elemento estruturante do Brasil e de algumas teorias criminológicas, buscamos neste artigo analisar de que forma as questões raciais operam no sistema de justiça criminal. Seguimos os rastros de duas decisões jurídicas que, ao sinalizarem que um réu branco “não possui o estereótipo padrão de bandido” (Tribunal de Justiça de São Paulo [TJSP], 2016) e que um réu negro é “seguramente integrante do grupo criminoso, em razão da sua raça” (Tribunal de Justiça do Paraná [TJPR], 2020), apontaram explicitamente o componente racial como critério de diferenciação. A análise desse mecanismo revela um continuum de práticas e equipamentos, como em abordagens policiais e audiências de custódias, que fixam o sujeito negro no lugar de suspeição e perigo.
Factors associated with umbilical cord clamping in term newborns
Authors: Strada Juliana Karine Rodrigues , Vieira Leticia Becker , Gouveia Helga Geremias , Betti Thais , Wegner Wiliam , Pedron Cecília Drebes
Published: March 2022

ABSTRACT OBJECTIVE: To identify factors associated with umbilical cord clamping in term newborns and to compare the recording of clamping time in the medical record with what was observed. METHOD: Cross-sectional study, with 300 mothers-infants, in a university hospital. Clamping time and medical records were observed, and a structured questionnaire was applied to postpartum women for sociodemographic variables. Bivariate analysis, multivariate Poisson Regression model, and Kappa concordance test were performed. RESULTS: The percentage of late/optimal clamping observed was 53.7%. The associated factors were skin-to-skin contact in the delivery room (PR = 0.76; 0.61–0.95; p = 0.014), position of the newborn below the vaginal canal (PR = 2.6; CI95%: 1.66–4.07; p < 0.001), position of the newborn at the vaginal level (PR = 2.03; CI95%: 1.5–2.75; p < 0.001), and need for newborn resuscitation in the delivery room (PR = 1.42; CI95%; 1.16–1.73; p = 0.001). Kappa concordance level of the professionals, records compared to the observation was: nurse 0.47, obstetrician 0.59, and pediatrician 0.86. CONCLUSION: the identification of associated factors and the comparison between recording and observing the clamping time can help in the planning and implementation of improvements for adherence to good practices at birth.
The emerald green tetra: a new restricted-range Hyphessobrycon (Characiformes: Characidae) from the upper rio Juruena, Chapada dos Parecis, Brazil
Authors: Dagosta Fernando Cesar Paiva , Seren Thomaz Jefrey , Ferreira Anderson , Marinho Manoela Maria Ferreira
Published: March 2022

ABSTRACT A new species of Hyphessobrycon is described from the rio Mutum, a tributary of the rio Juruena, rio Tapajós basin, Brazil. The new taxon can be distinguished from its congeners by the presence of a well-defined and relatively narrow dark midlateral stripe on body, extending from head to the middle caudal-fin rays, presence of a humeral blotch, distal profile of the anal fin falcate in males, 13-16 branched anal-fin rays (vs. 17-26), and 11 or 12 horizontal scale rows around caudal peduncle. The new species shows polymorphism regarding the presence of the adipose fin, and a discussion on this type of polymorphism across the family and its systematic implications is presented.
Population structuration and chromosomal features homogeneity in Parodon nasus (Characiformes: Parodontidae): A comparison between Lower and Upper Paraná River representatives
Authors: Azambuja Matheus , Marcondes Daiane Santana , Nogaroto Viviane , Moreira-Filho Orlando , Vicari Marcelo Ricardo
Published: March 2022

ABSTRACT The ichthyofauna of the La Plata hydrographic basin is divided into Upper and Lower Paraná River systems due to the geographic isolation of the Sete Quedas waterfalls, currently flooded by the lake of the Itaipu dam. In Parodontidae, pairs of species, or groups of cryptic species were described between these systems. Although genetic isolation and speciation have already been proposed in other species in the group, Parodon nasus has been maintained as a valid species and distributed throughout the La Plata river basin. In this perspective, specimens of P. nasus from four different sampling sites in the Upper and Lower Paraná River systems were compared regarding the karyotypes, molecular analyzes of population biology and species delimitation to investigate their genetic and population isolation in the La Plata river basin. Despite a geographic barrier and the immense geographic distance separating the specimens sampled from the Lower Paraná River system compared to those from the Upper Paraná River, the data obtained showed P. nasus as a unique taxon. Thus, unlike other species of Parodontidae that showed diversification when comparing the groups residing in the Lower versus Upper Paraná River, P. nasus showed a population structure and a karyotypic homogeneity.
Le Messager du Brésil (RJ, 1878-1884): trajetória em três movimentos
Authors: LUCA TANIA REGINA DE
Published: March 2022

RESUMO O objetivo deste artigo é analisar a trajetória do jornal Le Messager du Brésil, redigido em francês e impresso no Rio de Janeiro. A partir do estudo das coleções disponíveis, é possível estabelecer três momentos distintos que apontam o crescente envolvimento do periódico nos debates políticos brasileiros, cenário no qual o jornal esteve longe de permanecer como observador passivo. O exemplo convida a relativizar o lugar ocupado por periódicos publicados em língua estrangeira nas histórias da imprensa brasileira, que, no mais das vezes, os tomam como circunscritos a grupos específicos, esmaecendo sua atuação política.
Analysis of Social Skills and Functional Characteristics of Adolescents with Cerebral Palsy
Authors: Silva Letícia Thays Bessa , Lourenço Gerusa Ferreira
Published: March 2022

Abstract This study aims to describe the repertoire of adolescents with cerebral palsy in relation to social skills and to characterize their levels of gross motor function, communication, and functional activities. As an analytical observational study, 15 adolescents with cerebral palsy participated: five with articulated speech and ten without articulated speech. The instruments used were Identification Form; Social Skills Inventory for Students Without Articulated Speech; Social Skills Inventory for Adolescents; Expanded and Revised Gross Motor Function Classification System; Communication Function Classification System; and Pediatric Evaluation Disability Inventory Computer Adaptive Test - Adapted Brazilian Version. With quantitative and qualitative descriptive analysis, the results did not indicate a significant difference in the total score between groups, but the participants showed developmental deficits. Adolescents without articulated speech are more motor and communicatively compromised. Studies like this can contribute to the production of knowledge in the fields of Psychology, Special Education, and Social Skills.