bluuebunny/crossref_metadata_2025 huggingface dataset:
The Successful Implementation of Early Breastfeeding Initiation Judging From The Level Of Knowledge and Family Support At R.S Prasetya Husada Karangploso Malang
Authors: Mutmainah Mutmainah , Anggraeni Suci , Hidajaturrokhmah Nur Yeny
Published: April 2022

Background: Early Initiation of Breastfeeding (EIB) is the process of letting the baby suckle on its own after birth. The baby is placed on the mother's chest and the baby himself with all his efforts to find a nipple to feed immediately. Method: The design of this study used an analytic observational method with a cross sectional approach. The number of respondents was 55 people. The instrument used is a questionnaire. The results of data analysis from statistics show that respondents have good knowledge of early breastfeeding initiation as many as 44 people (80%), which provide good support as many as 45 respondents' families (81.8%) and 50 respondents (90.9%) implemented early breastfeeding initiation). Results: the results of the chis-quare analysis between the knowledge variable and the success variable early breastfeeding initiation obtained p-value = 0.002. it means that there is a significant relationship between knowledge about early breastfeeding initiation and the success of implementing early breastfeeding initiation. the results of the chis-quare analysis between the family support variable and the success variable early breastfeeding initiation obtained p-value = 0.001. Conclusion: there is a significant relationship between family support with the successful implementation of early breastfeeding initiation. the existence of a relationship between knowledge, family support and the success of early breastfeeding initiation can be influenced by age status where the majority of the respondents are early adulthood and can also be influenced by the level of education where the education level of the respondents is high school is also influenced by the parity of the respondents where most of the respondents are multiple parity
The Effect of Home Care Service Innovations in Increasing Patient Loyalty and Satisfaction
Authors: Bela Yohana Rangga , Sutrisno Joko , Rusmawati Aprin
Published: April 2022

Background: The increase in health care costs, large budget cuts make home care services a tool to reduce costs and length of care. As a result, home care services have developed into a complex issue and must be addressed with great care if one of the goals is to provide the best possible outcome for each individual. The purpose of this study was to find out "Study of Home Care Service Innovation in Improving Patient Loyalty and Satisfaction in the City of Kediri". Method: The design of this research is observational analytic with a cross-sectional approach. The sample size is 79 respondents. Sampling research using random sampling, data collection using questionnaires and the calculation process using the Wilcoxon test using SPSS 18.0 error 0.05. Results: The results of this study indicate that most of the respondents (72.2%) with good home care innovation are 57 respondents, most of the respondents (87.3%) with good loyalty are 69 respondents. more than half of respondents (59.5%) With very satisfied patient satisfaction, 47 respondents out of a total of 79 respondents 0.000 which means it is smaller than = 0.05, thus it can be said that H0 is rejected and H1 is accepted. Conclusion: Researchers can conclude that when there are good services carried out by nursing staff or home care services, good results will also be obtained, including patients who can trust and will continue to be loyal in using home care services at Gambiran Hospital, Kediri City
Factors Associated with the Incidence of Dengue Hemorrhagic Fever (DHF) at the Suruh Trenggalek Health Center
Authors: Putra Tri Adi , Ellina Agusta Dian
Published: April 2022

Background: Dengue Hemorrhagic Fever (DHF) is one of the public health problems in Indonesia which tends to increase in the number of patients and the wider its spread. The purpose of this study was to determine the factors for the occurrence of Dengue Hemorrhagic Fever (DHF) in the Public Health Center in Suruh Trenggalek. Method: The research design used is quantitative with a "cross sectional" approach. The sampling technique used is Simple Random Sampling with a sample of 108 respondents. Data analysis technique using Logistic Regression. Results: The results showed that there was a relationship between the habit of hanging clothes with the incidence of dengue hemorrhagic fever, with a p-value of 0.000 < = 0.05. The results showed that there was a relationship between the frequency of bathtub draining and the incidence of dengue hemorrhagic fever, with a p-value of 0.000 < = 0.05. The results showed that there was a relationship between the presence of larvae with a p-value of 0.000 < = 0.05. Simultaneous test results also show the influence of all variables on the incidence of dengue hemorrhagic fever with a p-value of 0.000 < = 0.05. Conclusion: It is hoped that there will be cooperation between local village government health officers and the community in order to minimize the incidence of dengue hemorrhagic fever
Physical Activity Patterns on Quality of Life in Chronic Kidney Failure Patients With Hemodialysis: Literature Review
Authors: Almeida Zeferino Ximendes de , Sutrisno Sutrisno , Saifullah Dedi
Published: April 2022

Background: Patients with chronic kidney failure require appropriate therapy to optimize kidney function. This therapy is not a drug, but as a substitute for kidney function. Renal function replacement therapy, such as hemodialysis is a routine medical treatment for chronic kidney disease. Method: The research design used a systematic use of several research journal articles published on the basis of Health. the health databases used include: Google Scholar, the national library and Pubmed with a time span of 2012 to 2020. Results: The results of this study are that there is an influence of physical activity patterns on the quality of life of patients with chronic kidney failure with hemodialysis. Conclusion: Patients with chronic kidney failure who undergo long-term hemodialysis therapy often feel worried about unpredictable disease conditions and disturbances that occur in life due to the disease they are experiencing. The patient's mindset changes because there are activities the patient does besides thinking about his illness
Analysis of the Supervision of the Head of the Room at the Ahmad Dahlan Muhammadiyah Hospital on the Performance of Nurses
Authors: Prisantika Emeylian Dhea , Korbaffo Anita Restu
Published: April 2022

Background: The problem of performance in hospitals is the center of attention because it involves the efficiency and effectiveness of human resources in achieving the goals and vision of the organization. Many factors affect performance, including supervisory factors from superiors which ultimately have an impact on overall performance results as an organization. Method: The design of this research is correlational with the population of all nurses in the inpatient ward of Muhammadiyah Hospital Ahmad Dahlan Kediri totaling 67 people. The sample is part of the population with a Stratified Random Sampling technique of 57 respondents. The data that has been collected is processed with the Spearman Rho statistical test with a significance of = 0.05. Results: The results of the analysis of the spearman rho test obtained a p-value = 0.000 which is less than the value of (0.05), it can be concluded that H0 is rejected, meaning that there is a relationship between the supervision of the head of the room and the performance of nurses at Ahmad Dahlan Hospital, Kediri. Conclusion: The results of this study also prove that supervision is able to improve the performance of nurses because when carrying out supervision there are certain actions that are evaluated by the head of the room against nurses, so that if the evaluation is corrected by nurses, it will be able to improve the performance of nurses
Level Knowledge of Mother's About Side Effects of Immunization on Compliance with Completeness Immunization for Toddlers in the Posyandu Area of Pakisaji Health Center
Authors: Susanti Ani , Anggraeni Suci
Published: April 2022

Background: The number of mothers whose babies do not get complete immunizations because mothers do not bring their babies to the posyandu or at the puskesmas for immunization because some of the heat when immunization will be carried out and the availability of time for working mothers so that they always delay immunization for toddlers so that there are still some mothers who have low levels of immunization. Low knowledge is one of the factors that cause mother's level of education to be anxious about bringing her baby to immunization. Method: The population was 35 respondents, namely mothers of children under five in the posyandu area of the Pakisaji Public Health Center. The sampling technique in this research is Simple Random Sampling. for research results using the contingency coefficient. Results: Data management and analysis using the coefficient of congruence test. The results of this study indicate that the mother's knowledge level (50%) and maternal compliance are 23 people (71.9%). The results of the coefficient of congruence test showed that the P-value = 0.014. Conclusion: There is a significant relationship between mother's knowledge about immunization side effects and compliance with the completeness of basic immunization for toddlers in the Posyandu area of Puskesmas Pakisaji
Dextromethorphan Drug Abuse Against Adolescent Learning Concentration: Literature Review
Authors: Ni’mah Kori’atun , Sutrisno Joko , Wardani Lingga Kusuma
Published: April 2022

Background: Dextromethorphan is often misused with excessive doses so that it gives a euphoric effect, a sense of calm, visual and auditory hallucinations. In fact, if taken in the recommended dosage, these pills are useful for suppressing coughs (antitussive) and phlegm-busting. However, it is often misused as a drug pill, because if you take too much, at least 10 pills at a time, it can cause nervous system depression that can become addictive. This study aimed to explore the abuse of the dextromethorphan class of drugs on adolescent learning concentration. Method: the researcher used a literature review design. The method used in the literature review is through a systematic approach to analyze data in a simplified approach. The keywords in this study are dextromethorphan drug abuse and concentration in learning. Results: Dextromethorphan is often misused with excessive doses so that it gives a euphoric effect, a sense of calm, visual and auditory hallucinations. Dextromethorphan intoxication or overdose can cause hyperexcitability, fatigue, sweating, slurred speech, hypertension, and can cause respiratory depression. Conclusion: Dextromethorphan drug abuse is associated with tolerance, addiction or addiction problems which can then develop into drug dependence (drug dependence). Students who experience deviant behavior in the form of drug abuse of the dextromethorphan class will experience impaired concentration while studying.
CK19 and PDX-1 Immunohistochemistry: Accuracy on Detecting Pancreatic Tumor and Its Metastases
Authors: Rosari Bayu Perkasa , Linggodigdo Michelle , Wijaya Yan Cahya , Stephanie Marini , Nur Rahadiani
Published: April 2022

BackgroundMetastatic adenocarcinoma of unknown origin remains a serious problem in oncology. Pancreatic cancer is often diagnosed when ithas already metastasized. Therefore immunohistochemistry (IHC) examination for detecting metastases of pancreatic origin is veryimportant IHC marker of Pancreatic duodenal homeobox-1 (PDX-1) has a good accuracy for detecting metastases of pancreaticorigin, however it is not readily available in many centers in Indonesia. Instead, IHC marker that is often being used is CK19. Thismarker is not specific, because it is also expressed by gastrointestinal and hepatobilliary tumors. This evidence-based case reportaims to determine the accuracy of CK19 compared with PDX-1 IHC for detecting pancreatic tumor and its metastases.MethodsLiterature searches were conducted on Pubmed/MEDLINE®, Scopus®, Cochrane®databases. Four articles about PDX-1 and 5 articlesabout CK19 that are relevant were found. Those articles were critically appraised.ResultsAll articles are considered valid, as they fulfilled the important criteria for journal validity. A study of CK19 IHC found that this markerhas 100% sensitivity and 6% specificity for diagnosing liver metastases from well-differentiated pancreatic ductal adenocarcinoma.Studies of PDX-1 IHC have different results; a study found that 27 out of 67 were PDX-1 positive in metastases of pancreaticadenocarcinoma origin, while another study found that PDX-1 has 72% sensitivity and 93% specificity for pancreatic neuroendocrinetumor, with 100% sensitivity and 75% specificity for pancreatic neuroendocrine tumor metastases.ConclusionCK19 IHC is highly sensitive for detecting adenocarcinoma metastases of pancreatic origin, thus it can be utilized as a screening test.However, CK19 IHC specificity for detecting adenocarcinoma metastases of pancreatic origin is low compared to PDX-1 IHC
New York Esophageal Squamous Cell Carcinoma-1 (NY-ESO-1) Expression in Synovial Sarcoma and Other Non Synovial Sarcoma as Potential Target for Immunotherapy
Authors: Ros Nirmawati,  , Siregar Nurjati Chairani , Evelina Kodrat
Published: April 2022

BackgroundSynovial sarcoma is a rare high grade soft tissue sarcoma. Nowdays, the available therapeutic modalities has not given asatisfactory result yet. Currently, there is a promising therapeutic strategy through immunotherapy targeting NY-ESO-1 which isexpressed on tumor. The aim of this study was comparing NY-ESO-1 immunoexpression between synovial sarcoma and itshistologic mimics i.e. malignant peripheral nerve sheath tumor (MPNST) and dermatofibrosarcoma protuberans (DFSP)MethodsA cross sectional study was done in 28 cases of synovial sarcoma, 10 cases of MPNST and 17 cases of DFSP from archievalmaterial in Department Anatomical Pathology, FMUI/RSCM from January 2013 to June 2019. Immunohistohemical stainning wasperformed using an antibody NY-ESO-1 and it was described positive if it was expressed in more than 50% of tumor with moderateto strong positive intensity.ResultsThere is a significant difference (p<0.001) in NY-ESO-1 immunoexpression among synovial sarcoma (18/28), MPNST (2/10) andDFSP (1/17). Furthermore, synovial sarcoma showed a significantly higher immunoexpression compared to MPNST (OR 7.2;p=0.016; power 68.7%) and DFSP (OR 28.8; p<0.001; power 98.9%).ConclusionSynovial sarcoma showed a higher expression of NY-ESO-1 thus makes it as a good candidates for immunotherapy. There aredifferences in the expression of NY-ESO-1 in synovial sarcoma against MPNST and DFSP.
SEÇİLMİŞ AVRUPA BİRLİĞİ ÜLKELERİ VE TÜRKİYE İÇİN MALİYE POLİTİKALARININ EKONOMİK BÜYÜMEYE ETKİSİ PANEL VERİ ANALİZİ ÖRNEĞİ
Authors: YİĞİT Yasemin İrem , GOVDERE Bekir
Published: April 2022

Geçmişten günümüze ekonomi literatüründe en çok tartışılan konulardan biri ekonomik büyümedir. Ekonomi yönetimleri para ve maliye politikası araçlarını iktisat politikaları amacı olan ekonomik büyümeye ulaşmak için kullanmaktadır. Bu çalışmada maliye politikalarının ekonomik büyümeye etkileri analiz edilmektedir. Bu amaçla 1995-2019 dönemi Almanya, Fransa, Hollanda, İtalya, Belçika, Polonya, Portekiz ve Türkiye olmak üzere sekiz ülkenin verileri kullanılmıştır. Bağımlı değişken ekonomik büyüme bağımsız değişkenler kamu harcamaları vergiler ve kamu borcu’ dur. Analiz edilen tüm ülkeler için söz konusu veriler panel veri ile analiz edilmiştir. Elde edilen temel bulgulara göre vergilerin ekonomik büyümeyi negatif etkilediği, kamu harcamalarının ekonomik büyümeye etkisinin çok düşük kaldığı görülmektedir.
Knowledge Level of Elderly with Diabetes Mellitus, Hypertension Against Covid-19 Vaccine in Panti Griya Jannati, Gorontalo City
Authors: Damansyah Haslinda , Sudirman Andi Nuraina , Kamiden Abdurahman Nur , Jannah Miftahul , Nusi Putri Indrawati
Published: April 2022

Elderly people are people whose biological systems undergo structural and functional changes due to advanced age. These changes can take place smoothly so that they do not cause disability or can occur very real and result in total disability. Hypertension is a silent killer where symptoms can vary in each individual and are almost the same as the symptoms of other diseases. Diabetes mellitus (DM) is a disorder of carbohydrate, lipid, and protein metabolism with various causes and is a chronic disease. A person with diabetes has high blood glucose levels, also known as hyperglycemia. The purpose of this community service is so that the elderly can increase their knowledge about hypertension and diabetes mellitus against the covid-19 vaccine. From the results achieved with this activity, the orphanage is very supportive and gives thanks to the Muhammadiyah University of Gorontalo in conducting outreach education in the form of leaflets and banners. The conclusion of this community service is that counseling can increase knowledge about hypertension and diabetes mellitus against the covid-19 vaccine
Increasing Independence in Hypertension at the Jannati Home for the Elderly, Gorontalo City
Authors: Sudirman Andi Nuraina , Damansyah Haslinda , Pakaya Gunardi , Aridi Ferawati , Pango Nun’ Ain
Published: April 2022

Hypertension can be defined as persistent blood pressure where the systolic pressure is above 140 mmHg and the diastolic pressure is above 90 mmHg. In the elderly population, the elderly here are a group of people or people who are old, they carry out religious activities carried out by themselves and others. Independence in the elderly includes the ability of the elderly to carry out daily activities such as: bathing, dressing neatly, going to the toilet, changing places. , can control urination and defecation, and can eat alone. Independence refers to psychosocial abilities which include freedom to act, not depending on other people's abilities, not being influenced by the environment, and free to regulate their own needs.
Low Doses Gamma Irradiation as Quarantine Treatment for Controlling Bactrocera zonata (Saund, 1841) and Its Impact on Guava Fruits Quality
Authors: Embaby Doaa Mohamed , Gabarty Ahlam , Abass Afaf Ahmed , EL-Said Eman
Published: April 2022

The current laboratory study investigates the effect of low doses of gamma irradiation range of (5-50 Gy) cesium cell- 137 on the different developmental stages eggs, 1st, 2nd , 3rd instars larvae and pupae of peach fruit fly, Bactrocera zonata. In addition to that the evaluation of phytosanitary irradiation dose on 3rd instar larvae and their effects on the biochemical quality of guava fruits were proven. The findings indicate that irradiation of eggs with dose 25Gy prevents adult emergence, while the dose 45Gy prevents pupation and the dose 50Gy prevents the hatchability of eggs. Moreover, exposure of larvae with the dose 50 Gy resulted in 98.5, 91 and 86 % mortality for the 1st, 2nd and 3rd instars larvae, respectively. No adult emergence was reported in 1st, 2nd and 3rd instars at the dose level 30, 35 and 45 Gy, respectively. The 3rd instar larvae appeared to be the most tolerant stage to radiation treatment than the 2nd and 1st larval instars. When adult emergence was used as a criterion for determination of the effective irradiation dose, 50 Gy was adopted for phytosanitary irradiation dose for B. zonata. Large scale confirmatory tests were applied to 25,000 3rd instar larvae of B. zonata in guava fruits resulting in non- F1 adults’ production with a confidence level of 91.8%. In conclusion, the irradiation dose of 50 Gy induces the inhibition of adult emergence of 3rd instar larvae and is suggested as a possible minimum dose for phytosanitary treatment of B. zonata fruit fly without causing significant effect (p ≤ 0.05) on some biochemical characteristics of guava fruits.
Pojęcie „ekonomizacji” w polskim prawie podatkowym
Authors: Werner Aleksander , Wierzbicki Jarosław
Published: April 2022

Rozważania zawarte w artykule zostały poświęcone modnemu współcześnie zagadnieniu ekonomizacji prawa
podatkowego. Koncepcja ta, z uwagi na elastyczność i niedookreśloność treściową pojęcia, bywa przywoływana
już to jako zagrożenie dla prawa, w tym podatkowego, już to jako wielka nadzieja i źródło potencjału interpretacyjnego.
Doręczanie pism za pomocą środków komunikacji
elektronicznej pełnomocnikom profesjonalnym, w tym
doradcom podatkowym, w postępowaniu podatkowym
po nowelizacji wynikającej z ustawy o doręczeniach
elektronicznych
Authors: Pietrasz Piotr
Published: April 2022

W artykule przedstawiono najnowsze rozwiązania prawne w zakresie doręczania pism w postępowaniu podatkowym
pełnomocnikom profesjonalnym, w tym doradcom podatkowym. Wynikający z ustawy z dnia 18 listopada
2020 r. o doręczeniach elektronicznych1 obowiązek posiadania przez adwokata, radcę prawnego i doradcę podatkowego
adresu do doręczeń elektronicznych koresponduje bezpośrednio z art. 144 § 5 Ordynacji podatkowej2.
Przepis ten reguluje obowiązek doręczania pism pełnomocnikowi będącemu adwokatem, radcą prawnym lub
doradcą podatkowym za pomocą środków komunikacji elektronicznej. Doręczanie pism pełnomocnikom profesjonalnym
za pomocą środków komunikacji elektronicznej nie ma charakteru bezwzględnego. Z art. 144 § 5 Ordynacji
podatkowej wynika bowiem możliwość doręczenia pisma tym podmiotom również w siedzibie organu podatkowego.
Ponadto w przypadku braku możliwości doręczenia pełnomocnikowi profesjonalnemu pisma na adres
do doręczeń elektronicznych (oraz w siedzibie organu podatkowego), czyli zgodnie z art. 144 § 1a powyższej
ustawy, mają zastosowanie art. 144 § 1b oraz § 1c tej ustawy.
Ochrona praw podatnika w świetle technologicznej transformacji systemu podatkowego
Authors: Feldo Katarzyna
Published: April 2022

Cyfryzacja podatków odgrywa istotną rolę w wielu obszarach dotyczących podatków na całym świecie, w tym w Polsce. Aparat skarbowy podejmuje działania innowacyjne, które skutkują znaczną transformacją systemu podatkowego. Proces ten jest korzystny dla organów podatkowych, gdyż ma on wpływ na wzrost efektywności ściągalności podatków, zwiększa dostęp organów podatkowych do coraz większej ilości danych o podatnikach, ułatwia im szybsze wykrywanie przestępstw podatkowych. Podatnicy z kolei oczekują, że digitalizacja systemu podatkowego uprości sprawozdawczość podatkową, sprawi, że klasyfikowanie na potrzeby podatkowe wykonywanych przez nich transakcji będzie łatwiejsze. Proces ten jest jednak także wielkim wyzwaniem dla każdej ze stron. Wiąże się z nim konieczność ponoszenia wysokich nakładów finansowych, ciągłego zdobywania wiedzy w zakresie zmieniających się przepisów oraz ich praktycznej implementacji w ustawowo określonym terminie. Nie ma wątpliwości, że digitalizacja systemu podatkowego jest procesem pozytywnym w swej istocie. Ważne jest jednak zbadanie, czy w ramach zachodzącego procesu zmian systemu podatkowego nie zapomina się o ochronie praw podatników, takich jak: prawo do wiedzy o obowiązujących przepisach prawa podatkowego, prawo do poufności danych biznesowych podatnika, ochrona jego prawa własności. Przeprowadzona analiza wskazuje, że ustawodawca i aparat skarbowy w ramach transformacji cyfrowej systemu podatkowego koncentrują się w głównej mierze na raportowaniu podatkowym, na efektywności ściągalności podatków, lecz zapominają o właściwej ochronie praw podatników.
Zawód doradcy podatkowego w Niemczech a możliwe
kierunki zmian w regulacji doradztwa podatkowego
w Polsce
Authors: Sarnowski Jan , Selera Paweł , Bartosiak Anna
Published: April 2022

Upływ 25 lat funkcjonowania ustawy z dnia 5 lipca 1996 r. o doradztwie podatkowym1 w Polsce stanowi dobrą
okazję do podsumowań i formułowania wniosków oraz propozycji kierunków zmian obowiązującej regulacji.
Szczególnym źródłem inspiracji dla polskiego prawodawcy mogą być w tym zakresie rozwiązania stosowane w
Republice Federalnej Niemiec (RFN), gdzie zawód doradcy podatkowego ma dużo dłuższą tradycję. Punktem
odniesienia dla ewentualnych zmian może być m.in. wprowadzona w Niemczech specjalizacja w ramach wykonywania
zawodu doradcy podatkowego. Przeniesienie tego rozwiązania na grunt polskiego prawa mogłoby się
przyczynić do wzrostu prestiżu i rozpoznawalności zawodu doradcy podatkowego w Polsce.
Industrija 4.0: uspješna upotreba novih tehnologija i neka zabrinjavajuća događanja u Austriji
Authors: Malisa Viktorijo
Published: April 2022

Deset godina nakon pokretanja njemačkog projekta za razvoj industrije "Industry 4.0" s ciljem da se cijela industrija više oslanja na korištenje informacijske tehnologije, pokazuje se da u nekim područjima postoje prednosti, u drugim nedostaci ili znatna potreba za daljnjim istraživanjem. Važno je da nove tehnologije ne ugroze postignutu sigurnost i zdravlje na radu, već ih dodatno unaprijede. Ovaj rad govori o različitim primjerima "Industrije 4.0" iz austrijske industrije. Koristeći primjere, istaknuti su različiti novi razvoji i prikazane su prednosti i nedostaci iz današnje perspektive, te preporuke za daljnja istraživanja. Da bi se industrijska promjena uspješno implementirala, potrebno je postaviti nove temelje i izraditi standardi, na čemu rade nekoliko institucija u Njemačkoj u sklopu radnih grupa.
Dimenzijska tačnost i tolerancije u aditivnoj proizvodnji
Authors: Lemeš Samir , Zaimović-Uzunović Nermina , Bešlagić Ernad , Varda Kenan
Published: April 2022

Važni pokazatelji kvaliteta za proizvode proizvedene metodom aditivne proizvodnje (AP) uključuju tačnost dimenzija, tolerancije i hrapavost površine. Ovaj rad opisuje inovativni referentni standard koji je dizajniran i proizveden pomoću 3D printera koji koristi stereolitografiju niske snage (LFS) i koji je kontroliran na koordinatnoj mjernoj mašini. Referentni standard sadrži osnovne geometrijske oblike koji se koriste za provjeru odstupanja od nominalnih dimenzija i zadatih karakteristika iz 3D CAD modela. Razvili smo strategiju automatskog mjerenja baziranu na 3D modelu objekta i plan upravljanja na osnovu prethodno definisanih dozvoljenih tolerancija. Izmjerili smo odstupanje od nominalnih dimenzija, položaja i oblika, uključujući cilindričnost, ravnost i paralelnost. Rezultati su otkrili velika odstupanja od dimenzija i prihvatljiva odstupanja od oblika proizvedenog referentnog standarda.
Dimensional accuracy and tolerances in additive manufacturing
Authors: Lemeš Samir , Zaimović-Uzunović Nermina , Bešlagić Ernad , Varda Kenan
Published: April 2022

Important quality indicators for products made by Additive Manufacturing (AM) methods include dimensional accuracy, tolerances, and surface roughness. This paper describes a novel benchmark part designed and manufactured by a Low Force Stereolithography (LFS) 3D printer and controlled on a coordinate measuring machine. The benchmark part contains basic geometric shapes used to check the deviation from the nominal dimensions and given features from the 3D CAD model. We have developed an automatic measurement strategy based on a 3D object model and a control plan based on previously defined allowable tolerances. We have measured the deviation from nominal dimensions, positions, and form, including cylindricity, flatness and parallelism. The results revealed large deviations in dimensions and acceptable deviations in the shape of a manufactured benchmark part.
Der Weltbezug der Künste
Authors: Jähnig Dieter
Published: April 2022

Das Leitmotiv des Buches ist die Einsicht, dass die Künste, auch die Musik, von Haus aus nicht nur Erkenntnis-Gegenstände sondern selber Erkenntnis-Quellen sind. Dieser Sachverhalt besteht aber aus einer Vielfalt von Aspekten, in der Zusammenhänge und Unterschiede zugleich im Spiel sind, was hier an drei Paradigmen: Schelling, Nietzsche und Kant, gezeigt wird. Dabei handelt es sich nicht um eine historische Entwicklung, also ein Nacheinander, sondern um das Nebeneinander gleichermaßen legitimer Gepräge. Am Ende des Buches steht eine Konkretisierung der Schelling-Thesen an Bildbeispielen, die von antiken Bildwerken über Caspar David Friedrich und William Turner bis zu Paul Klee reichen. »Der Philosoph und Kunsttheoretiker Dieter Jähnig hat einen bemerkenswerten Text, eine Art Summe seiner Forschung zum Verhältnis zwischen Philosophie und Kunst vorgelegt. Bemerkenswert ist dieser Text aus mehreren Gründen, zum einen, weil er - mit Schelling und Nietzsche - zeigt, dass Kunst nicht zum Objekt gemacht werden darf, sondern selbst eine Quelle des Weltverstehens und der Zeitkritik ist, zum anderen, weil er - mit Platon, Schelling und Nietzsche - in souveräner Weise den mimetischen Charakter der Kunst nicht als Nachahmung, sondern als schöpferische Form des Lebens darstellt. Schließlich zeigt Jähnig im Blick auf Kants dritte Kritik, dass die Kunst der Philosophie Grenzen setzt. Das Stichwort hier ist ›Freiheit nicht als Selbstbestimmung sondern als Gunst‹. All dies sind Schlaglichter einer gedanklichen Helligkeit, die kein anderer mir bekannter Text auf das Verhältnis der Kunst zur Philosophie wirft. Jeder an Philosophie und Kunst Interessierte, ob als Studierender oder Lehrender oder einfach Leser, sollte diesen Text kennen.« Wilhelm Vossenkuhl
Metaphysik und Erfahrung in Kants praktischer Philosophie
Authors: Laschet Oliver
Published: April 2022

Kant verfolgt in seinen ethischen Grundlegungsschriften das wiederholt erklärte Ziel, „eine reine Moralphilosophie zu bearbeiten, die von allem, was nur empirisch sein mag und zur Anthropologie gehört, völlig gesäubert wäre“ (Grundlegung, KW IV, 13). Die damit zugleich beanspruchte strikte Trennung einer erfahrungsfreien Metaphysik praktischer Vernunft von empirischer Anthropologie wird im vorliegenden Buch kritisch in Hinblick auf ihre systematische Tragfähigkeit für die von Kant ausgearbeitete Moralphilosophie überprüft. Dabei zeigt sich, dass Kant den begründungstheoretischen Status der empirisch-anthropologischen Elemente, die er bei der konkreten Ausgestaltung seiner moralischen Pflichtenlehre offenkundig in Ansatz bringt, weder hinreichend expliziert noch geltungstheoretisch in Hinblick auf die Kohärenz seiner dichotomischen Wissenschaftsaufspaltung reflektiert. Vielmehr überschätzt Kant die metaphysische Reichweite und den streng apriorischen Charakter seiner Ethik und Rechtsphilosophie insbesondere in seinen diesbezüglichen programmatischen Äußerungen. Erst durch die Korrektur dieses Selbstverständnisses anhand einer systematischen Rekonstruktion und Beurteilung der Kantischen Argumentationsschritte erschließt sich die substanzielle Bedeutung seines Terminus „Metaphysik der Sitten“. Im Rahmen dieser Korrektur tritt zudem die Parallelität der Kantischen „Metaphysik der Sitten“ zu seinen Metaphysischen Anfangsgründen der Naturwissenschaft zutage, die - unbeschadet ihres apriorischen Geltungsanspruchs - ebenfalls auf empirische Begriffe und Fakten Bezug nehmen.
The Dynamic of Residential Energy Demand Function: Evidence from Natural Gas
Authors: Jaouad Malzi Mohamed
Published: April 2022

This analysis uses annual data on residential gas use for 29 Organization for Economic Cooperation and Development nations from 2005 to 2016 to look at per capita energy demand. The effect of price and income on natural gas demand elasticities has been studied in the past, but most research have ignored demographic aspects. The goal of this study is to incorporate these characteristics into natural gas demand modeling. A dynamic panel system dubbed the Generalized Method of Moments (GMM) estimator was used to address the endogeneity issue. The following are the study’s main findings: First, the residential sector consumes more natural gas per capita as the population grows. Second, the consumption of per capita residential natural gas in Organization for Economic Cooperation and Development countries is decreasing as the population ages. Finally, as the population density rises, so does per capita gas consumption.
Cultural Competence as a Response to Structural Racism in Latino Substance Use and Access to Care in the United States
Authors: Guerrero Erick , Khachikian Tenie , C. Cervantes Richard , Kaplan Charles , D. Olate Rene , B. Unger Jennifer
Published: April 2022

Disparities in substance use disorders (SUD) and access to treatment among individuals identified as Latino/Hispanic have become a significant public health issue in the United States. National efforts to identify, understand, and eliminate such disparities have highlighted the role of structural racism in Latino health. In this chapter, we offer a critical review of how Latino substance use and access to care may be impacted by discrimination, acculturation stress, and other mechanisms of structural racism. As structural racism is represented by policies, systems, structures, and norms that deny and/or minimize cultural strengths and disempower culturally diverse groups and their attempts to invest in their wellness, we highlight how cultural competence may reduce the risk of SUD and may enhance access to treatment among Latinos. We conclude by highlighting policies and responsive organizational practices that may improve Latino health.
Local Tubers Production and Value Chain: Evidence from Sangihe Island Regency, Indonesia
Authors: N. Kairupan Agustinus , H. Joseph Gabriel , G. Kindangen Jantje , C. Paat Paulus , Polakitan August , Polakitan Derek , Erik Malia Ibrahim , Hutapea Ronald
Published: April 2022

Sangihe Islands Regency is an archipelago located in the border area of the Philippines. The area is far from the Provincial Capital and the Indonesian capital of Jakarta. Therefore, it is sometimes difficult for people to access basic needs, especially food. On the other hand, they have access to alternative food consumed hereditary. For instance, there are plenty of tuber food crops, including cassava, sweet potatoes, and taro. Thus, there is a need for discussion in empowering people on the benefits of tubers such as productions, value chain, and potential development. The methodological approach used is descriptive exploratory, where the data collected is secondary from the desk review related to the potential and food conditions of the people in the area. Several local tuber crops are suitable for development as a staplefood on Sangihe Islands. The development supported by the adequate technological application can optimally increase product value and revenue. Furthermore, those aspects need systematically and synergistically patterned.
Variable Selection in Nonlinear Principal Component Analysis
Authors: Katayama Hiroko , Mori Yuichi , Kuroda Masahiro
Published: April 2022

Principal components analysis (PCA) is a popular dimension reduction method and is applied to analyze quantitative data. For PCA to qualitative data, nonlinear PCA can be applied, where the data are quantified by using optimal scaling that nonlinearly transforms qualitative data into quantitative data. Then nonlinear PCA reveals nonlinear relationships among variables with different measurement levels. Using this quantification, we can consider variable selection in the context of PCA for qualitative data. In PCA for quantitative data, modified PCA (M.PCA) of Tanaka and Mori derives principal components which are computed as a linear combination of a subset of variables but can reproduce all the variables very well. This means that M.PCA can select a reasonable subset of variables with different measurement levels if it is extended so as to deal with qualitative data by using the idea of nonlinear PCA. A nonlinear M.PCA is therefore proposed for variable selection in nonlinear PCA. The method, in this chapter, is based on the idea in “Nonlinear Principal Component Analysis and its Applications” by Mori et al. (Springer). The performance of the method is evaluated in a numerical example.
Nanoemulgel: For Promising Topical and Systemic Delivery
Authors: Sultana Nazneen , Akhtar Juber , Badruddeen  , Irfan Khan Mohammad , Ahmad Usama , Arif Muhammad , Ahmad Mohammad , Upadhyay Tanmay
Published: April 2022

Nanoemulgel delivery system is a fusion of two different delivery systems, wherein the physical state of drug containing nanoemulsion is changed by adding it to the gel matrix, thus enabling more lipophilic drugs to be used in treatment therapies. It solves the major issues such as limiting use of lipophilic drugs, poor oral bioavailability, and unpredictable pharmacokinetic and absorption variations. Simultaneously, its nongreasy nature and easily spreading ability support the patient compliance. Nanoemulgel can be widely used in the treatment of acne, pimple, psoriasis, fungal infection, and inflammation cause by osteoarthritis and rheumatoid arthritis. The delivery of drug via ocular, vaginal, dental, and nose to brain routes for the treatment of diverse local and systemic ailments for instance alopecia, periodontitis, and Parkinson’s are possible. In the cosmetic industries, UV absorber nanoemulgel protected skin from sunburn.
Pests, Diseases, Nematodes, and Weeds Management on Strawberries
Authors: Bozbuga Refik , Uluisik Selman , Aridici Kara Pınar , Yuceer Semiha , Gunacti Hale , Gok Guler Pakize , Ince Elen , Nilufer Yildiz Hatice , Tetik Ozcan
Published: April 2022

Strawberry is an important crop for many features, including being rich in vitamins and minerals. In addition to fresh consumption, it has been appealing to a wide range of consumers in recent years. Its cultivation is in flat areas, slopes, and areas where other crops are limited. Many pests and diseases that are the main biotic stress factors cause significant crop losses in strawberry cultivation. The aim of this chapter is to reveal biotic stress factors and their management. Several plant-parasitic nematodes, fungal diseases, weeds, pests, virus diseases, and bacterial diseases are the main biotic stress factors in plant growing and fruit ripening. The preparation of this book chapter is based on previously published sources and researches and manuscripts. In this section, it is aimed to provide readers with new perspectives in terms of collecting data on nematodes, diseases, pests, weeds, and fruit ripening of strawberry plants. The effect and mechanism of those biotic stress factors on strawberry growing are discussed and revealed in this chapter.
PET-CT Imaging and Applications
Authors: Shaikh Sikandar
Published: April 2022

PET-CT is an important imaging modality which is well established in the recent years. The role of the molecular imaging in the evaluation of the various pathologies has been increased due to the various technological advances, radiotracer advances and also in the research. This chapter is emphasised to give the broader and better overview of the PET-CT imaging which will be used for various applications in broader fields. These advanced imaging techniques will form the basis of the different clinical applications of the PET-CT. Thus, there will have more precise applications in various pathologies which will increase the sensitivity and specificity of the different disease processes. The understanding of the basic techniques is important before being used in various pathologies. The techniques can be routine or special like the puff cheek technique for the better evaluation of the oral malignancies. The newer concept of the dual time point imaging which is being used to differentiate between the various infective and inflammatory lesions from the malignant pathologies. This chapter emphasises the use of the various techniques for various focussed clinical applications.
Sustainability and Religion: Mutual Implications
Authors: Oviedo Lluis
Published: April 2022

Whether sustainability goals advance depends greatly on the human factor, or the set of beliefs, values, and attitudes held by entire populations, besides governments, authorities or boards. Recognizing the role that the human factor plays might ensure a better consideration of religious bodies or churches when trying to design more sustainable complex systems, a point frequently ignored in secular societies where the weight of religious beliefs seems to be dismissed as insignificant. Post-secular arrangements could open the door to a greater engagement from religious organizations and individuals. At the same time, it is important for churches and theological reflection to assume the sustainability aim at the centre of their interests and development. There are some exceptions, as the case of apocalyptic-driven religious forms, which are little interested in sustainability, and could expect a rather catastrophic end of times. However, most religious expressions should be more concerned about contributing to sustainable programs.
ALK Translocation in ALK-Positive Mesenchymal Tumors: Diagnostic and Therapeutic Insights
Authors: Jung Minsun , Moon Kyung Chul , Bae Jeongmo , Kim Tae Min , Kim Miso , Jeon Yoon Kyung , Lee Cheol
Published: April 2022

Context.—

A wide spectrum of mesenchymal tumors harboring ALK gene rearrangements has been identified outside the archetypal example of ALK-positive inflammatory myofibroblastic tumors.

Objective.—

To evaluate the molecular pathology of unusual ALK-positive mesenchymal tumors and their response to ALK-targeted treatments.

Design.—

Seven patients with ALK-positive mesenchymal tumors, including inflammatory epithelioid cell sarcoma, undifferentiated sarcoma, histiocytic neoplasm, smooth muscle tumor of uncertain malignant potential (STUMP), and atypical fibrohistiocytic tumor, were included on the basis of aberrant ALK immunoexpression. Patients with inflammatory myofibroblastic tumors were excluded from the study. ALK gene rearrangement was investigated either by fluorescence in situ hybridization or next-generation sequencing.

Results.—

ALK was immunolabeled in all patients, diffusely (≥50%) in 6 patients and partially (10%–50%) in 1 patient. ALK gene rearrangement was discovered in 5 of the 6 available patients. The 3′-partners of ALK fusion were identified in 3 of 4 investigated patients as follows: PRKAR1A-ALK (ALK-positive histiocytic neoplasm), TNS1-ALK (STUMP), and KIF5B-ALK (ALK-positive atypical fibrohistiocytic tumor). We failed to discover ALK translocation in 1 patient with ALK-positive inflammatory epithelioid cell sarcoma. However, transcriptomic investigation showed that this tumor was significantly enriched with ALK-related pathways, which suggested activation of ALK through a nontranslocation pathway, as a constitutive oncogenic mark in this tumor. ALK-targeted inhibitors, which were administered to 3 patients with metastatic diseases, achieved partial remission in 1 patient with ALK-positive inflammatory epithelioid cell sarcoma and stable disease in patients with ALK-positive undifferentiated sarcoma and STUMP.

Conclusions.—

Molecular investigation of ALK-positive mesenchymal neoplasms could allow for an accurate diagnosis and personalized treatment.
Seroprevalence and estimation of the impact of SARS-CoV-2 infection in older adults residing in Long-term Care Facilities in Chile
Authors: Rubilar Paola , Hirmas Macarena , Matute Isabel , Browne Jorge , Little Cedric , Ruz Gonzalo , Aguilera Ximena , Ávila Carlos , Vial Pablo , Gutknecht Mackenzie Tania
Published: April 2022

Introducción Las personas mayores tienen más riesgo de enfermar gravemente y fallecer por COVID-19. Esta vulnerabilidad aumenta en quienes viven en establecimientos de larga estadía, debido a hacinamiento, mayor dependencia física y contacto con los trabajadores. La evidencia sobre el impacto de la pandemia de estos establecimientos en países de medianos y bajos ingresos ha sido escasa. El objetivo es determinar la seroprevalencia de la infección por SARS-CoV-2 en personas mayores que residen en establecimientos de larga estadía. Así como estimar el impacto global de la infección después de la primera ola de la pandemia. Métodos Diseño transversal con 2099 residentes en tres regiones de Chile, realizado entre septiembre y noviembre 2020. Anticuerpos fueron medidos con test rápido contra SARS-CoV-2. Se estimó el impacto de la infección con los residentes seropositivos, los residentes con antecedentes de reacción en cadena de la polimerasa de transcripción inversa positiva, y residentes que murieron por COVID-19. Análisis bivariado entre el resultado serológico y región, sexo, edad, antecedentes de COVID-19 y dependencia física fueron realizados. Además, realizamos un análisis de correlación entre la seroprevalencia de los centros por municipio y la tasa acumulada de casos confirmados. Resultados La seroprevalencia de anticuerpos en las tres regiones fue 14,7% (intervalo de confianza del 95%: 13,2 a 16,3%). El impacto real de la infección se estimó en 46,4% y la tasa de letalidad en 19,6%. La seroprevalencia de los residentes de los centros por comuna se correlacionó positiva y significativamente con la frecuencia de la enfermedad a nivel comunal. Conclusiones Seroprevalencia superior a la de la población general, observándose un alto impacto de la infección por COVID-19 al final de la primera ola de la pandemia. El lugar en el que se encuentran los establecimientos está directamente relacionado con la tasa de seroprevalencia en ellos. Sistemas de vigilancia epidemiológica deben aplicarse con prontitud para establecer medidas de prevención y control.
Who is Rationalising? On an Overlooked Problem for Kant’s Moral Psychology and Method of Ethics
Authors: Sicker Martin
Published: April 2022

I critically examine the plausibility of Kant’s conception of rationalising, a form of self-deception that plays a crucial role for Kant’s moral psychology and his conception of the functions of critical practical philosophy. The main problem I see with Kant’s conception is that there are no theory-independent criteria to determine whether an exercise of rational capacities constitutes rationalising. Kant believes that rationalising is wide-spread and he charges the popular philosophers and other ethical theorists with rationalising. Yet, his opponents could, in turn, charge him with rationalising and some theorists, namely Act-Consequentialists, seem to be in an even stronger position to charge Kant with rationalising than vice versa. In response, I propose standards that do not assume a specific normative theory and that become apparent when we look at clear-cut abuses of rationality. These standards of minimally decent reasoning can help us diagnose rationalising. I develop these standards by looking at inadequate uses of rational capacities that should strike us as problematic regardless of the specific ethical theory we adopt. I emphasise that even an abuse of rational capacities can yield true results and that we can never tell from a single judgement that someone rationalises. Rather, we must look for patterns.
Categorical Moral Requirements
Authors: Bakhurst David
Published: April 2022

This paper defends the doctrine that moral requirements are categorical in nature. My point of departure is John McDowell’s 1978 essay, “Are Moral Requirements Hypothetical Imperatives?”, in which McDowell argues, against Philippa Foot, that moral reasons are not conditional upon agents’ desires and are, in a certain sense, inescapable. After expounding McDowell’s view, exploring his idea that moral requirements “silence” other considerations and discussing its particularist ethos, I address an objection that moral reasons, as McDowell conceives them, are fundamentally incomplete in ways only a full-bloodedly Kantian appeal to pure practical reason can remedy. I conclude that the objection fails: ordinary moral reasons do not stand in need of a grounding in Reason. There is no prospect of deriving them from a supreme principle of morality or other canons of rationality. Ordinary reasons are sufficient in themselves, though their significance can be elucidated and illuminated by various strategies — some broadly Aristotelian, some drawing inspiration from Kant’s formula of humanity — in ways that can strengthen and vindicate them. Notwithstanding the failure of the objection, I conclude by reflecting on how Kantian insights can yet play a significant role in a McDowellian view of moral deliberation and moral education.