bluuebunny/crossref_metadata_2025 huggingface dataset:
THE EFFECTS OF KINDERGARTEN SPORTS SCHOOL ON BILATERAL COORDINATION OF PRESCHOOL AGE CHILDREN
Authors: Uzunović Slavoljub , Đorđević Nenad , Nikolić Dušan , Stošić Dejan , Marković Jovan , Petrović Vladan , Kostić Lora
Published: October 2018

The research was conducted with the aim of determining to what extent and in what manner the kindergarten sports school program affects the coordination of preschool children. The sample consisted of 57 preschool age children. The control group comprised 31 children and the experimental one 26 children, aged 6 years ± 6 months. The experimental group applied the sports school program for a period of 8 weeks (2 x 45 minutes each week). The control group only had regular activities in the kindergarten. The level of bilateral coordination in children was determined applying seven tests and a level of balance applying nine tests at the initial and final measurement. At the initial measurement, experimental and control groups showed similar results, while the experimental group showed significantly better results at the final measurement. The tests applied in the research were taken from the BOT-2 battery of tests: the Bruininks-Oseretsky test of Motor Proficiency (Bruininks, 1987; Bruininks and Bruininks, 2005, taken from Cools et al, 2009), where body coordination as a separate composite is assessed by subtests of bilateral coordination and balance. The obtained data were processed by the SPSS 20 statistics software, and ANCOVA was used to determine the effects of the sports school program. It is assumed that the experimental program has influenced the improvement of the results between two assessments of the bilateral coordination (on three tests) and balance estimates (on one test). The obtained results point to the need for a wider application of similar programs in working with preschool age children.
FACTOR ANALYSIS AS OPTIMAL METHOD IN DETERMINING MOTORIC ABILITIES AND THE QUALITY OF LIFE, HEALTH AND SOCIAL WELLNESS OF PERSPECTIVE JUDOKAS
Authors: Popović Dragan , Mitić Dragana , Popović Jasna , Boli Evagelija , Samouilidou Evdokia , Dolga Milan
Published: October 2018

The goal of this study is a comparative analysis of the possibilities of physical education for children with health problems and the current status in boys and girls. Understanding the concept of impaired health is a precondition for the realization of the training process and possible integration in the process of physical education, according to the structure of health disadvantages. Quality of life assessment is performed on three levels. The first level are items that are given in the form of a statement. On the second level, item-like particles are observed in the sub-segments (scales that cover different dimensions of health and quality of life). The raw scores of each scale are transformed into standardized ones with a possible value of 1-4, which facilitates the interpretation of the results. The third level represents total physical and psycho-social health. Up to this level, there are certain mathematical procedures, based on the individual scale scores. Comparative analyses in regard of the cultural and gender specificities are provided, based on MANOVA and DISCRA analyses, within the introductory part, and 11 scales of the Questionnaire. Analysis of the data point out major differences in the possibility of physical activity application in children with medical conditions, with a special overview of boys and girls from diverse cultural and social backgrounds, in Serbia and the Northern Aegean region of Greece.
INFLUENCE OF MORPHOLOGICAL CHARACTERISTICS ON RUNNING PERFORMANCE OF ENDURANCE ATHLETES
Authors: Petrovic Ivana , Marinković Marjan
Published: October 2018

Running is a popular form of physical activity and can be carried out through several different distances. Morphological characteristics, such as skin fold thickness, limb girth and length, body weight and body fat percentage have an impact on endurance running. The objective of this systematic review study is to collect and analyze studies about the influence of morphological characteristics on running performance of endurance athletes. Based on an analysis of electronic databases and the inclusion criteria set, 20 studies were included in the analysis. The length of the extremities and the sum of the skin folds thickness have the highest statistical significance as the predictor. The results of the analyzed studies indicate that slim limbs, longer legs, lower total skin fold thickness and lower body fat percentage are some of the characteristics that can be good predictors for competitive success and a model to be tended during the preparation period of male and female endurance runners.
EFFECTS OF DEVELOPMENTAL GYMNASTICS ON MOTOR FITNESS IN PRESCHOOL GIRLS
Authors: Madić Dejan , Cvetković Milan , Popović Boris , Marinković Dragan , Radanović Danilo , Trajković Nebojša
Published: October 2018

The aim of this research was to determine the effects of developmental gymnastics on motor fitness in preschool girls. This study was performed on a sample of 56 healthy preschool girls that were divided into two groups, a developmental training group and a control group. Motor fitness tests were used from several test batteries: the 20m dash, Obstacle course backwards, Standing broad jump, Arm plate tapping, Seated straddle stretch, Bent arm hang, Sit ups. The basic characteristics of developmental gymnastic training process consisted of station and circuit work and obstacle courses two times a week lasting for 60 min with intensity around 160-180bpm. After the training intervention, the training group showed significant (p < 0.05) improvements in almost all the parameters analyzed (e.g., Obstacle course backwards; Standing broad jump; Arm plate tapping; Bent arm hang and Sit ups) compared with pretest values, with percentages of change and ES ranging from 13.3% to 48.2% and 0.64 (moderate) to 1.20 (large), respectively. No significant changes were observed in the control group after the training intervention except for the standing broad jump and arm plate tapping (p < 0.05). This study provides evidence on the effectiveness of developmental gymnastics programs for the optimal development of young children’s motor fitness.
RELATIONS OF FITNESS PARAMETERS AND MORPHOLOGICAL CHARACTERISTICS OF SEVEN -YEAR - OLD OBESE CHILDREN
Authors: Živković Danijela , Ranđelović Nebojša , Đorđević Marija , Pantelić Saša , Malobabić Marina
Published: October 2018

The aim of this research was to determine the relations of fitness parameters and morphological characteristics of seven-year-old obese children. The sample of participants consisted of 103 obese children (63 girls and 40 boys), first grade students (mean age 7.04 years) of elementary schools in Nis. The following fitness parameters were measured: HR in load, VO2max (ml), HR in peace, bend forward - bend backward - throw test, hand taping, 20m dash with a standing start, Abalakov test and forward bend on the bench test. Morphological characteristics were determined by measuring 13 parameters of longitudinal and transversal dimensions of skeleton, volume and body mass, as well as subcutaneous fat tissue. Canonical correlation analysis was used to determine the relations between the set of variables representing fitness parameters and the set of variables of morphological characteristics. Based on the coefficients of canonical correlation analysis, it can be concluded that the spaces of morphological characteristics and fitness parameters are interconnected with two pairs of statistically significant canonical factors (p˂.05 and p˂.01). The general analysis of the relationships between the first pair of canonical factors suggests that subjects with higher circular dimensionalities of the body, accentuated adiposity and body mass tend to have poorer results in motoring tasks requiring body flexibility, explosive leg strength and running speed, and also have poorer results in the parameters of cardiorespiratory fitness. It can be concluded that obesity in young school age has negative implications on the fitness parameters in children, and therefore on their overall growth and development.
EFFECTS OF TECHNICAL AND TACTICAL CHARACTERISTICS ON THE PERFORMANCE OF THE TABLE TENNIS PLAYERS
Authors: Ivanek Vladimir , Đukić Branko , Mikić Branimir , Smajic Miroslav , Doder Dragan
Published: October 2018

The aim of the research was to determine the effects of applied technical and tactical characteristics of table tennis players on their success in competitions. The representative sample consisted of 48 top senior table tennis players from Bosnia and Herzegovina, age 18 and 36, selected on the basis of a qualification tournament. The measuring instruments for this study included eight assessment tests for the table tennis players' technical and tactical characteristics and one test for assessing success in table tennis competitions. Technical and tactical characteristics of the participants were evaluated by five experts who analyzed the efficacy of technical and tactical characteristics of the players on a scale ranging from 1 to 5. The methods of processing the results included descriptive statistical procedures, the multiple correlation coefficient, the determinant coefficient and a multiple regression analysis. The results indicate that technical and tactical characteristics have a major impact on the player's performance and are essential for table tennis success. Based on the value of the regression coefficients and their significance, it may be concluded that the 5 variables statistically significantly contribute to the regression model are: the efficiency of the serve; the efficiency of preventing the attack of the opponent and preparation of the players’ own attack; confidence when attacking across the table; the efficiency in the active defence and the efficiency of movement during the game. In the hierarchy of significance, the most important variables are the serve efficiency and efficiency of preventing the attack of an opponent and preparation of the player's own attack. The efficiency of the serve allows an attacker to realize technical and tactical ideas and usually gain initiative in the game. By returning a serve we can prevent or at least make it harder for the opponent to attack again. A serve return can also allow us to take the initiative
El concepto de gobierno moderado como hilo conductor en el constitucionalismo temprano de Hispanoamérica
Authors: Timmermann Andreas
Published: October 2018

Este trabajo muestra un aspecto preponderante que ha recibido poca consideración: el constitucionalismo temprano en Hispanoamérica siguió una idea central y superior, que vinculó las distintas formas de Estado y de gobierno con la monarquía española y condujo al presidencialismo. Esta idea estuvo arraigada tanto en la tradición jurídica ibérica como en los sistemas jurídicos estadounidense y anglosajón. Se trata del principio de la moderación, que en el ámbito del institucionalismo es traducido como el principio de "gobierno moderado".
La búsqueda de un concordato entre México y la Santa Sede a fines del siglo XIX
Authors: Bautista García Cecilia Adriana
Published: October 2018

Avanzado el gobierno de Porfirio Díaz en México, la relación EstadoIglesia intenta consolidarse en un pacto oficial a través de una serie de intentos de la Santa Sede por reanudar sus relaciones diplomáticas con el gobierno mexicano. El presente análisis añade algunos elementos para abordar ese problema, en la circunstancia del proceso de romanización de la Iglesia mexicana.
Hacia una educación jurídica práctica y globalizada en Colombia
Authors: Monroy-Cely Daniel-Alejandro
Published: October 2018

Las problemáticas que enfrenta actualmente la formación de los abogados en Colombia están relativamente identificadas y son parte incluso de la agenda gubernamental en materia de educación superior. Sin embargo, las estrategias y propuestas de solución respecto de aquellas lucen aún precarias e insuficientes. En este orden, el escrito propone que una parte importante de dichas problemáticas pueden afrontarse de manera efectiva, mediante la promoción y profundización de una formación jurídica más globalizada y práctica en las escuelas de derecho. Para efectos, el documento parte de diagnósticos más generales y relativos a la educación legal tanto en Latinoamérica como en el resto del mundo. Con lo anterior, se pretende sentaruna base preliminar para una discusión más profunda acerca del tipo formación que reciben los estudiantes de derecho en Colombia.
Presencia, utilización y aprovechamiento de las TIC en la formación académica estudiantil
Authors: Paz-Pérez Luis-Alberto , Tamez-González Gerardo , Hernández-Paz Abraham , Leyva-Cordero Oswaldo
Published: October 2018

El presente trabajo empírico se desarrolla desde la perspectiva de la comunidad estudiantil en cuanto a la existencia y utilización práctica de las tecnologías de la información y comunicación (TIC) en el ámbito de las tareas académicas cotidianas de la Facultad de Ciencias Políticas y Administración Pública de la Universidad Autónoma de Nuevo León. La propuesta tiene como objetivo describir la percepción de los alumnos sobre las TICy su grado de aplicación en su formación académica. El proyecto es de tipo cuantitativo, transversal, desarrollado a través de un cuestionario aplicado a una muestra estratificada por semestre. Los hallazgos detectados durante el proceso y los resultados obtenidos, permiten develar la existencia de equipamiento suficiente y adecuado, con lo cual se concluye que existen las condiciones óptimas para ampliar la oferta educativa y ofrecer programas formativos totalmente a distancia, utilizando las TIC.
Creación del Observatorio de Responsabilidad Social Educativa en América Latina
Authors: Martínez-Domínguez Luis-Manuel , Porto-Pedrosa Leticia
Published: October 2018

Este artículo reflexiona sobre la importancia de crear en América Latina el Observatorio de Responsabilidad Social Educativa como entidad competente para analizar las prácticas que se llevan a cabo desde las instituciones educativas no universitarias y ofrecer asesoramiento para optimizarlas. A lo largo de las últimas décadas se han dado pasos importantes en esa búsqueda de la excelencia en el ámbito de la educación en diferentes países latinoamericanos. En cuanto a la educación universitaria, la responsabilidad social se considera un punto de partida indispensable para mejorar el impacto de estas instituciones en su comunidad y la sociedad en general, con la finalidad última de lograr una mejor formación para el desarrollo sostenible. Desde el Observatorio se promueve un ranking de instituciones educativas en el que se priorice este tipo de responsabilidad fundamentado en el debate, la reflexión y las buenas prácticas orientadas hacia esta nueva exigencia en las organizaciones y el bien común.
THE IDEA OF CALIPHATE IN THE MUSLIM WORLD (LATE 19TH — EARLY 20TH CENTURY): CHALLENGES AND REGIONAL RESPONSES
Authors: Kirillina S. A. ,  Safronova A. L. ,  Orlov V. V.
Published: October 2018

The article deals with theoretical approaches to the essence of Caliphate as they were formulated by Middle Eastern and South Asian Islamic thinkers. The distinguishing characteristics of Pan-Islamic and Pan-Ottoman conceptions and their perception in the Muslim communities of Arab provinces of the Ottoman Empire and among the Sunni Muslims of South Asia are analyzed. The study explores the historical and cultural background of the appeal of Caliphatist values for Muslims of various ethnic origins.
THE INTRACONFESSIONAL RELATIONS IN THE REPUBLIC OF DAGESTAN IN THE CONTEXT OF CONTACTS OF ETHNIC COMMUNITIES
Authors: Djabrailov Yu. D.
Published: October 2018

In this article the author studies the speciﬁ cs of correlation between ethnic and religious identities in Dagestan of the Post-Soviet period. It is emphasized that, despite the supranational and integrating character of Islam, the modern ethnically marked social and economic problems inﬂ uence on the relations between ethnic communities more their common religious ideology.
THE ESTABLISHMENT OF ISLAMIC EDUCATION IN POST-SOVIET BASHKORTOSTAN: BASIC STAGES, CONCEPTS AND RESULTS
Authors:  Khabibullina Z. R.
Published: October 2018

The article deals with the process of development of Islamic education in the Republic of Bashkortostan since the renaissance of religious life in the post-Soviet period. Conceptual changes in the system of religious education, which take place under the inﬂ uence of modern trends and social challenges, are analyzed on the example of a particular region. The author points out the results of transformations in the sphere of Islamic education in Bashkortostan. Russia has a state program for the development of Islamic education, the main goal of which is the development and strengthening of the national system of Islamic education, which can reduce the number of people wishing to study in foreign Islamic centers. All levels of Muslim education are represented in Bashkortostan now. However, the process of creating and implementing a uniﬁ ed concept of Islamic education in the republic, as well as in the country as a whole, is not yet completed.
Supporting Family Physician Maternity Care Providers
Authors: Goldstein Jessica Taylor , Hartman Scott G. , Meunier Matthew R. , Panchal Bethany , Pecci Christine Chang , Zink Nancy M. , Shields Sara G.
Published: October 2018

Maternity care access in the United States is in crisis. The American Congress of Obstetrics and Gynecology projects that by 2030 there will be a nationwide shortage of 9,000 obstetrician-gynecologists (OB/GYNs). Midwives and OB/GYNs have been called upon to address this crisis, yet in underserved areas, family physicians are often providing a majority of this care. Family medicine maternity care, a natural fit for the discipline, has been on sharp decline in recent years for many reasons including difficulties cultivating interdisciplinary relationships, navigating privileging, developing and maintaining adequate volume/competency, and preventing burnout. In 2016 and 2017, workshops were held among family medicine educators with resultant recommendations for essential strategies to support family physician maternity care providers. This article summarizes these strategies, provides guidance, and highlights the role family physicians have in addressing maternity care access for the underserved as well as presenting innovative ideas to train and retain rural family physician maternity care providers.
An “Invaluable Skill”: Reflections on Abortion Training and Postresidency Practice
Authors: Greenberg Samantha , Nothnagle Melissa
Published: October 2018

Background and Objectives: The goal of this study was to explore family medicine residents’ experiences with abortion training and identify positive and negative influences, and facilitators and barriers to providing abortion care.
Methods: We conducted a qualitative study of recent graduates of an urban family medicine residency in the Northeast United States with an opt-out abortion curriculum. Individual recorded interviews were conducted with two classes of graduated residents until data saturation was reached. Data were coded and interpreted by both authors using the template analysis method.
Results: Twenty residents completed interviews. Most trainees had limited or no abortion exposure prior to residency but were open to learning abortion care. By graduation, residents reported confidence in providing options counseling for unintended pregnancy. Overall, residents felt more comfortable providing medication abortion than aspiration abortion. Many reported feeling less emotional reaction to medication abortion and noted more technical and logistical barriers to learning aspiration abortion. Logistical barriers impede integration of medication abortion into practice for many, but were perceived to be less difficult to overcome than barriers to aspiration abortion integration. All participants agreed abortion care fits into the scope of primary care. Due to a variety of barriers, few of those who had not previously planned to become abortion providers after graduation incorporated it in their practice.
Conclusions: Abortion training prepared residents to counsel women with unintended pregnancy, but numerous barriers inhibit integration of abortion care into practice. Given limited abortion training resources and fewer perceived barriers to medication abortion provision, family medicine residencies may consider focusing training on medication abortion.
Competencies to Guide a Leadership Curriculum for Family Medicine Chief Residents
Authors: Marvel M. Kim , Wozniak Janell , Reed Alex J.
Published: October 2018

Background and Objectives: Chief resident leadership competencies are neither clear nor standardized. The goal of this project was to identify specific leadership skills for chief residents and to develop a self-assessment tool.
Methods: Chief residents from 10 family medicine residencies participated in focus groups to identify leadership skills required to be an effective chief resident. The ideas generated by participants were grouped into 10 competencies and a self-assessment tool was developed. The tool has been used to help chief residents self-assess their leadership strengths and weaknesses, and to identify teaching priorities for biannual leadership workshops.
Results: The self-assessment instrument was completed by 83 chief residents over 5 years. Mean ratings range from 3.19 to 3.57 on a 5-point scale (low to high competency). The self-ratings of residents starting their chief year compared to residents at the end of their chief year showed an increase in 9 of the 10 competencies.
Conclusions: The leadership competencies are a useful tool to identify training priorities and to help chief residents or other leaders within a residency program identify skills for further development.
Burnout and Job Satisfaction Among Family Medicine Residency Coordinators:
Authors: Ofei-Dodoo Samuel , Scripter Cassie , Kellerman Rick , Haynes Cheryl , Marquise Maria Eliza , Bachman Caren Sue
Published: October 2018

Background and Objectives: Research into rates of burnout and job satisfaction among family medicine residency coordinators is nonexistent. Coordinators play a pivotal role in medical education, sometimes have multiple roles and titles, and often work in stressful environments. The goals of this study were to explore the prevalence of, and relationship between, burnout and job satisfaction among family medicine residency coordinators.
Methods: This national wellness study involved 307 family medicine residency coordinators. Modified questions of the Professional Quality of Life Scale, Version 5 were used to measure participants’ burnout and job satisfaction rates. The authors used chi-square tests, Pearson’s r correlations, and multiple linear regression to analyze the data.
Results: The response rate was 72% (307/429), with 24% of family medicine residency coordinators reporting high, 51% reporting moderate, and 26% reporting low rates of work-related burnout. Twenty-eight percent of the family medicine residency coordinators reported high, 46% moderate, and 26% low job satisfaction. There was a significantly negative relationship between job satisfaction and work-related burnout, r (306)=-.638, P<0.001. Regression explained 42% of variance in job satisfaction, and showed that burnout (β=-.62) and years on the job (β=.15) were significant predictors of job satisfaction (R=0.64; F [5, 277]=40.28, P<.001).
Conclusions: The results demonstrate that family medicine residency coordinators are generally satisfied with their work and reported moderate to high degree of burnout rates.
Investigación-acción en la asignatura Estadística I, utilizando el enfoque evaluar para aprender
Authors: Sánchez-Godínez Elisa
Published: October 2018

La evaluación de los aprendizajes desde el enfoque de evaluar para aprender permite desarrollar capacidades tanto cognitivas como emocionales para aprender a aprender. Este trabajo pretende dar a conocer la experiencia en la revisión de la asignatura Estadística I del Diplomado en Administración de la UNED, bajo el enfoque de Evaluar para aprender y utilizando la investigación-acción como una metodología que parte de un diagnóstico para reflexionar y generar acciones correctivas. En este proceso se identificaron dos debilidades principales: la autoevaluación y la retroalimentación. Se aplicó una encuesta a una muestra de 140 estudiantes en la que se manifestó que los juegos y prácticas incluidos en la plataforma Moodle fueron de mucha utilidad, de igual manera, las actividades de autoevaluación y la retroalimentación brindadas.
The relationship between corporate governance and information disclosures: Evidence from the Philippines
Authors: Chantachaimongkol Nunthapin , Chen Shuwen
Published: October 2018

This paper aims to investigate the impact of board characteristics and auditors on the disclosure practices of listed companies in the Philippines. This study used a self-constructed research instrument, namely the ASEAN Disclosure Index, to assess the extent of corporate disclosure of 21 the Philippines’ listed companies from 2011-2015, made out of 105 observations. The index covers 212 information items, with three attributes: financial information (76 items), non-financial information (68 items) and strategic information (68 items). An empirical result reports that the result reveals that an audit committee independence is positively significant at 95% level while board size and a number of board meetings held in the year are negatively significant at 95% level. For other variables covering board independence, a number director participation rates, gender diversity, CEO duality, a number of audit committee meetings, a number of audit committee participation rates and quality of external auditors, no significant relationship was found. This study contributes to the literature by offering a new instrument for assessing the extent of corporate disclosure in Southeast Asia region and also providing a novel viewpoint into the relationships between corporate governance mechanisms on information disclosure practices in a context of developing countries like the Philippines. Definitely, the contributed empirical evidence of this study might also help regulators for enhancing the level of corporate disclosure in the Philippines as well as neighboring countries in Southeast Asia region.
Magnetohydrodynamic flow and heat transfer over a moving cylinder in a nanofluid under convective boundary conditions and heat generation
Authors: Abdel-Wahed Mohamed , El-Said Essam
Published: October 2018

In this paper, the effect of convective boundary conditions, heat generation, Brownian motion, and thermophoresis on heat transfer characteristics of a moving cylinder embedded into cooling medium consists of water with nanoparticles are studied. The governing boundary-layer equations transformed to ODE using similarity transformation method and then solved analytically using optimal homotopy asymptotic method for the general case. The velocity, temperature, and concentration profiles within the boundary-layer plotted and discussed in details for various values of the different parameters. Moreover, the effect of boundary-layer behavior on the surface shear stress, rate of heat and mass transfer investigated.
Experimental investigation of solar/wind hybrid system for irrigation in Konya, Turkey
Authors: Kose Faruk , Aksoy Muharrem , Ozgoren Muammer
Published: October 2018

In this study, an experimental research for agricultural irrigation was completed for a renewable hybrid power generation system consisting of photovoltaic panels and wind turbine which can be considered as an alternative to Diesel generators used for pumping applications. Generated electricity was used to power a 300 W DC-driven submersible pump at 2.5 m depth of the ground level. Overall efficiencies of the wind turbine and cell efficiencies of the photovoltaic panels in July 2011 were calculated as 33.3% and 10.07%, respectively. It was observed that the daily mean of produced electricity by the system in July was enough to pump daily average 44.1 m3/day of water from the depth of 2.5 m and totally 1368 m3 of water during the month. It was calculated that the amount of pumped water is sufficient to meet water need of the agricultural products that were 12.4 decares of sugar beet, 13.0 decares of potatoes, 13.4 decares for corn, 13.6 decares green bean and 10.8 decares for sun flower with the drip irrigation method. It was demonstrated that the renewable hybrid energy system enables to save the 10410 USD on energy in twenty-year period after the basic payback period of 5.7 years. In addition, the net present value and internal rate of return of the project were found to be 7361 USD and 12.6%, respectively.
Pygo2 Regulates Adiposity and Glucose Homeostasis via β-Catenin–Axin2–GSK3β Signaling Pathway
Authors: Xie Yuan-Yuan , Mo Chun-Li , Cai Yi-Huang , Wang Wen-Jie , Hong Xin-Xin , Zhang Kun-Kun , Liu Qing-Feng , Liu Yun-Jia , Hong Jing-Jing , He Ting , Zheng Zhong-Zheng , Mo Wei , Li Bo-An
Published: October 2018

Wnt/β-catenin signaling plays a key role in regulating adipogenesis through indirectly inhibiting the expression of C/EBPα and peroxisome proliferator–activated receptor γ (PPARγ); however, the detailed molecular mechanism remains poorly understood. Moreover, the factor(s) that determines the Wnt/β-catenin output level during adipogenesis is also not completely defined. In this study, we showed that Pygo2 exhibited a declined expression pattern during adipocyte differentiation, resulting in an attenuated Wnt/β-catenin output level. The mechanism study indicated that Pygo2 inhibition led to the downregulation of Axin2, a constitutive Wnt target, in the cytoplasm. Consequently, Axin2-bound GSK3β was released and translocated into the nucleus to phosphorylate C/EBPβ and Snail, resulting in an increase in the DNA binding activity of C/EBPβ and decreased protein stability of Snail, which subsequently activated the expression of C/EBPα and PPARγ. Consistent with this, embryonic fibroblasts from Pygo2−/− mice exhibited spontaneous adipocyte differentiation, and adipocyte precursor–specific Pygo2-deficient mice exhibited increased adiposity with decreased energy expenditure. We further showed impaired glucose tolerance and decreased systemic insulin sensitivity in Pygo2-deficient mice. Our study revealed an association between Pygo2 function and obesity or diabetes.
Obesity-Associated miR-199a/214 Cluster Inhibits Adipose Browning via PRDM16–PGC-1α Transcriptional Network
Authors: He Linyun , Tang Mowei , Xiao Ting , Liu Hailan , Liu Wei , Li Guangdi , Zhang Feng , Xiao Yalun , Zhou Zhiguang , Liu Feng , Hu Fang
Published: October 2018

miRNAs are important regulators of differentiation, development, and function of brown and beige fat cells. In this study, we identify the role of the miR-199a/214 cluster in the regulation of brown and beige adipocyte development and thermogenesis in vitro and in vivo. We show that expression of the miR-199a/214 cluster is dramatically decreased during brown and beige adipocyte differentiation and in response to cold exposure or β-adrenergic receptor activation. The cluster levels are significantly upregulated in the adipose tissues of obese mice and human subjects. Overexpression of the miR-199a/214 cluster suppresses brown adipocyte differentiation and inhibits thermogenic gene expression and mitochondrial respiration, whereas knockdown of the cluster increases thermogenic gene expression and mitochondrial function in beige adipocytes. In addition, inhibition of the miR-199a/214 cluster promotes beiging effects in vivo. We further show that miR-199a/214 suppresses brown adipocyte differentiation and beige fat development by directly targeting PRDM16 and peroxisome PGC-1α, two key transcriptional regulators of adipose browning. Together, these observations reveal that the miR-199a/214 cluster is a key negative regulator of brown and beige fat development and thermogenesis.
A kabai meteorit újravizsgálatának fontosabb eredményei
Authors: Kubovics Imre , Bendő Zsolt , Gál-Sólymos Kamilla , Ditrói-Puskás Zuárd , Miklós Dóra Georgina , Ivanics Balázs
Published: October 2018

A kabai meteoritban többféle eredetű és összetételű hőálló (refraktorikus) ásvány, hőállóásvány-társulás mutatható ki. Legtöbbet és legjellegzetesebbeket a fehérzárványhalmazok, továbbá a kerekded–ovális kondrumszerű képződmények, valamint a 100–200 μm átmérőjű „kondrumok” tartalmaznak. A meteorit felszínén is látható – általában 10–18 mm hosszú – sárgásfehér „zárványokat” a mikroszkópi vizsgálatok szerint többnyire teljesen szabálytalan alakú, „szaggatott” szerkezetű, szemcsés halmazok alkotják. Helyenként egymás közvetlen közelében több különböző méretű halmazból álló csoport alakult ki, valószínűleg egy nagyobb darab széttöredezése eredményeképpen. A halmazok mozaikos szerkezete is ezzel magyarázható. Az uralkodóan 100–400 μm méretű, gyakran különböző összetételű, részben alapanyagot is tartalmazó szemcsék általában bonyolult zónás szerkezetűek. Leggyakoribb, illetve legnagyobb mennyiségű összetevője a magot alkotó, de kisebb mennyiségben rendszerint a többi övben is megjelenő közönséges spinell. A következő öveket részben gehlenit, de uralkodó mennyiségben, titánban és alumíniumban gazdag monoklin piroxének alkotják. Egyes szemcsék körül záró övként a forsterit is megjelenik.

A kerekded–ovális megjelenésű, kondrumszerű képződmények, valamint a kis méretű kondrumok az előzőekkel megközelítőleg, illetve részben azonos ásványi összetételűek, az alkotók mennyiségi arányában, valamint a képződési sorrendben azonban jelentős különbségek mutatkoznak. Az uralkodó magalkotó fázisok általában változó mennyiségű zárványt tartalmaznak. Például a gehlenitben rendszerint kevés perovszkit és részben spinell, a közönséges spinellben pedig többnyire sok perovszkit mutatható ki. Külön kiemelkedő a kerek „felhőszerű” halmaz magjának túlnyomó részét alkotó magnéziumtartalmú gehlenit nagy mennyiségű, mégpedig 72% platinát, továbbá — többek között — irídiumot és kevés hafniumot is tartalmazó „zárványa”. A kerekded–ovális képződményeken belül az alakzat, a szerkezet, valamint a jellemző ásványok alapján gehlenitet, közönséges spinellt, valamint normatív hercinitet és korundot tartalmazó változatot különböztethetünk meg. A jellemző uralkodó ásványok rendszerint az adott változat magját alkotják, és általában jelentős mennyiségű „zárványt” — főleg kerekded perovszkitot tartalmaznak. A mag körüli övezetet főleg spinell és monoklin piroxének alkotják. Egyes változatokban azonban az 5–7% Na2O-t tartalmazó — esetenként önálló övet alkotó — amorf anyag („mezosztázis”) is jelentős mennyiséget képvisel. Ez az öv valószínűleg a Mokoia-meteoritban kimutatott (MACPHERSON et al. 1983) filloszilikátokhoz hasonló összetételű (normatív) rétegszilikátokat is tartalmaz.
Középső-miocén sziláscet (Cetacea: Mysticeti) humerusok a Pécs, danitzpusztai homokbányából
Authors: Cserpák Ferenc
Published: October 2018

Az utóbbi húsz év gyűjtéseinek köszönhetően nagy mennyiségű sziláscet felkarcsont került elő egyetlen lelőhelyről, a Pécs melletti danitzpusztai homokbányából. A vizsgált humerusok a középső-miocénből (szarmata, badeni?) áthalmozottan, a pannóniai homokban találhatók.

A területről összesen 19 db — kettő kivételével — közgyűjteményben elhelyezett humerust tanulmányoztam, melyek három taxonba sorolhatóak: cf. Cetotherium priscum (EICHWALD 1840); „Cetotherium” aff. maicopicum (SPASSKI 1951); és Cetotheriidae indet.

A danitzpusztai cf. C. priscumba sorolt felkarcsontokkal azonos taxont képviselnek a Pécs-Vasasról, a horvátországi Samoborról származó leletek, valamint a Bécsi-medence anyagából előkerült három példány.

A „Cetotherium” aff. maicopicum (SPASSKI 1951) egyedei méreteikben ugyan kisebbek, de morfológiai jellegeikben a Keleti-Paratethysből leírt „Cetotherium” maicopicum (SPASSKI 1951) felkarjával mutatnak nagyfokú egyezést, így azok feltehetően a genushoz tartozó új faj tagjai lehetnek.

A Cetotheriidae indet.-be sorolt kisméretű humerusnak nem sikerült megtalálni morfológiai és metrikus karaktereiben a párhuzamait, így nagy valószínűséggel egy új taxont képvisel.
Entrevista com Prof. Dr. Sérgio Fonseca da Teixeira
Authors: Pernambuco Andrei Pereira
Published: October 2018

Entrevistamos o Diretor da Escola de Educação Física, Fisioterapia e Terapia Ocupacional da UFMG e Editor Chefe do Brazilian Journal of Physical Therapy, Dr. Sérgio Fonseca Teixeira.
Karabuğday: Bileşimi ve Gıdalarda Kullanılması
Authors: Kılıç Su , Elmacı Yeşim
Published: October 2018

Karabuğday (Fagopyrum esculentum Moench ve Fagopyrum tataricum (L.) Gaertn), bileşiminde yüksek oranda protein, diyet lif, vitamin, mineral madde, temel çoklu doymamış yağ asitleri bulundurmakta, başta rutin olmak üzere önemli antioksidanlar ve fenolik bileşenler için kaynak oluşturmaktadır. Protein biyo-yararlılığının yüksek olmasının yanı sıra gluten içermemesi nedeni ile çölyak hastalarının beslenmesine uygun, besleyici değeri yüksek önemli bir alternatif olmaktadır. Karabuğday, çeşitli yöresel ürünlerde ham bileşen olarak yer alıp insan beslenmesindeki yerini günümüze kadar korumuştur. Beslenmedeki öneminin ve sağlık üzerine olumlu etkilerinin son yıllarda yeniden keşfedilmesiyle birlikte beslenmede ve birçok gıda formülasyonunda önemli bir bileşen olarak artan bir popülerlik ile kullanılmaktadır. Bu çalışmada, karabuğdayın kimyasal bileşimi ve karabuğday kullanılarak geliştirilen gıdalar hakkında bilgi verilmiştir.
Comparison of Mutton Charollais Lambs and Their Cross Lambs Born from Indigenous Fat Tailed and F1 Prolific Breed Ewes
Authors: Kutluca Korkmaz Müzeyyen , Emsen Ebru
Published: October 2018

The objective of this study was to evaluate the effects of dam breed on lambs sired by Charollais rams and purebred Charollais lambs obtained via embryo transfer. Frozen Charollais semen and embryos, used to obtain crossbreed and purebred Charollais lambs, were imported from elite flock with pedigrees and progeny test in Canada.The study was conducted on the crossbred Charollais lambs born from Tushin, and Romanov F1 ewes (Romanov × Morkaraman), and Charollais lambs born from Awassi, Morkaraman and Tushin surrogate ewes. The data was collected on 61 lambs (23 Charollais: CH, 20 Tushin × Charollais: F1 CH and 18 Charollais × Romanov F1:COR) from birth to weaning. Average weights at birth for CH, F1 CH and COR lambs were 4.32 ± 0.18 kg, 4.17 ± 0.18 kg, 3.18 ± 0.19 kg and at the age of 60 days were 21.20 ± 1.07 kg, 20.94 ± 0.84 kg, 18.13 ± 0.91 kg, respectively. The genotype of dams significantly affected birth and weaning weights of crossbred lambs, but not average daily live weight gain (ADG). Litter size had constant significant effect on the traits evaluated. Survival rates of crossbred lambs from birth to weaning were affected by the dam genotype. Birth weights and survival rates of CH lambs born from embryo transfer were affected by recipient genotypes and Awassi ewes were found to be the best surrogate mothers.
Kırşehir Ahi Evran Üniversitesi, Ziraat Fakültesi, Tarım Ekonomisi, 40100 Kırşehir
Authors: Doğan Hasan Gökhan
Published: October 2018

Tarımsal destekleme politikaları ülkelerin tarım sektörünün sürdürülebilir olması açısından önemlidir. Politika araçları ülkeler ve dönemler bazında değişiklik gösterebilmektedir. Bu araştırmada, Türkiye‘de arz açığı yaşanan ayçiçeği, soya, aspir ve kolza ekiliş alanlarına fark ödemesi desteklerinin etkileri araştırılmıştır. Araştırma, 1994-2016 yıllarını kapsamaktadır. Granger Nedensellik Testi ve Johansen Cointegration Testi‘nden yararlanılmıştır. Elde edilen sonuçlara göre, fark ödeme desteklerinin ayçiçeği üretici kararları üzerinde etkisi istatistiksel olarak önemli bulunmuştur. Aspir, kolza ve soya ekiliş alanlarında ise etkisi önemli görülmemiştir. Ancak, incelemeye alınan ürünlerin cari fiyatları ile fark ödeme desteklerinin etkileşim içerisinde olduğu belirlenmiştir. Buna göre, geçmiş dönemlerde destekleme politikalarında yaşanan sorunlar da göz önünde bulundurularak fark ödemesi desteklerinin katılımcı bir yaklaşımla tekrar tartışılması önerilebilir. Söz konusu desteklerin sürdürülmesi piyasa fiyatları açısından koruyucu nitelikte olduğundan bir gereklilik olarak ifade edilebilir. Ancak, bir taraftan desteklerin bütçe içerisindeki yeri diğer taraftan üretici gelirlerine olan etkileri göz önünde bulundurularak dengeli bir politika yaklaşımından uzaklaşılmamalıdır.
Health Care Utilization
Authors: 2018 MIDWEST SAPH
Published: October 2018

Faculty Discussant: A. Simon Pickard, PhDArticle 1: Real-World Cost-Effectiveness Analysis of Allogeneic Hematopoietic Stem Cells Transplantation vs. Hydroxyurea Therapy in Children with Sickle Cell DiseaseJifang Zhou, MD, MPH; Gregory S. Calip, PharmD, MPH, PhDArticle 2: Fondaparinux Sodium Compared with Low Molecular Weight Heparins for Thromboprophylaxis among the Patients with Orthopedic Immobility: A Systematic Review and Meta-AnalysisArun Kumar PharmD, MS; Ashna Talwar, BPharm; Wenchen Wu, PhD; Joel F Farley, PhDArticle 3: Differences by Primary Insurance in 30-day All-cause Readmission for Patients Undergoing Breast Cancer SurgeriesMing Chen, MS, MSPharm; Shelley Irene White-Means, PhD, MA; Sam Li, PhD, MSArticle 4: Seasonal Variation in Heart Failure Hospitalizations in the United StatesKendra Y. Foster, MS; Linnea A. Polgreen, PhDArticle 5: Antidiabetic Medications among People 20 years and Older and with Diabetes in the United StatesJulie Zhiying Zhao, MPH; Angeline Carlson, PhDArticle 6: Healthcare Utilization in Type 2 Diabetes Patients Using DPP-4 inhibitors and GLP-1 AgonistsSajan Pandya BPharm; Monica Hwang, PhDArticle 7: Estimating the Impact of the Food and Drug Administration’s (FDA) Unapproved Drug Initiative (UDI) on Drug Prices and ExpendituresSharma D; Schumock GT; Saffore C; Edwards SA; Walton SM
Pharmacist Contributions
Authors: 2018 MIDWEST SAPH
Published: October 2018

Faculty Discussant: Andrea Kjos, PharmD, PhD Article 1: The Evolution of the Field Of Social and Administrative Pharmacy: Past, Present, and Future: A Network Perspective Daniel Ricci, PharmD, MS; Betty Chewning, PhD Article 2: The Developing Role of Community Pharmacists in Facilitating Care Transitions Kooyman Chase; Matthew J. Witry, PharmD, PhD Article 3: Exploring the Utilization of Community Pharmacists to Facilitate Linkage and Retention in Care of People Living with HIV Adati Tarfa, PharmD, RPh; Olayinka Shiyanbola, PhD, BPharm Article 4: The Roles of Clinical Pharmacists in Diabetes Management: What Do Minority Patients with Uncontrolled Type 2 Diabetes Have to Say? Nadia A. Nabulsi, MPH; Connie H. Yan, PharmD; Ben S. Gerber, MD, MPH; Lisa K. Sharp, PhD Article 5: An Ethical Case Study of PBM Practices’ Impact on Providers Jacob J. Drettwan, Graduate Student; Andrea L. Kjos, PhD, PharmD Article 6: Operationalizing Occupational Fatigue in Wisconsin Pharmacists Taylor Watterson, PharmD; Kevin Look, PharmD, PhD; Michelle Chui, PharmD, PhD
Patient Experiences
Authors: 2018 MIDWEST SAPH
Published: October 2018

Faculty Discussant: Olihe Okoro, PhDArticle 1: Patient Experiences at Enhanced-Service Pharmacies in IowaChen Huang, Graduate Student; William Doucette, PhD, FAPhA, RPh; Michael Andreski, RPh, PhD; Anthony Pudlo, PharmD, MBAArticle 2: The Perspective of African-born HIV Minnesotans of their Interaction with PharmacistsAlina Cernasev, PharmD, MSc; William L. Larson, PharmD, BCGP, BCACP; Cynthia Peden-McAlpine, PhD, ACNS, BS; Todd Rockwood, PhD, MA, BS; Paul Ranelli, PhD, MS; Olihe Okoro, PhD, MPH, MPharm; Jon C. Schommer, PhDArticle 3: Association between Insurance Characteristics and Patient Activation among Medicare Beneficiaries with Type 2 DiabetesDandan Zheng, MS, PhD Student; Joseph Thomas III, PhD, ProfessorArticle 4: How Do Health Literacy And Risk Perception Impact Older Adult Misuse Of Over-The-Counter Medications?Apoorva Reddy, BS; Jamie Stone, MS; Michelle Chui, PharmD, PhDArticle 5: A Qualitative Approach to Patient Experiences in MigraineDeepika Rao, MS Candidate; Elham Heidari, PharmD, MS Candidate Vincent Giannetti, PhD; Andrea R. Pfalzgraf, PhD, MPH; Carroline Lobo, MS, PhDArticle 6: The Medication Experience of African American Women with Early Stage Chronic KidneyDiseaseLisa Hillman, PharmD, BCACP; Olihe Okoro, PhD, MPH; Djenane Ramalho de Oliveira, PhD; Jon Schommer, PhDArticle 7: Pharmacist-Delivered Patient-Centered Care: Exploring an Untested AssumptionAnthony W. Olson, PharmD; Jon C. Schommer, PhD
Percepção sobre a gestão estratégica de pessoas em uma instituição de ensino superior pública federal
Authors: Mendes Monica Scóz , De Souza Gabriela Mattei , Moreira Katia Denise , Dalmau Marcos Baptista Lopez
Published: October 2018

Frente a um contexto globalizado, cujo modelo econômico exige da área de gestão de pessoas dinamicidade e proatividade, a gestão estratégica de pessoas, em oposição ao mecanicismo do passado, surge como elemento catalisador. Assim, alinhando o fenômeno da gestão estratégica de pessoas ao de competências, este estudo tem como objetivo verificar se a Universidade Federal de Santa Catarina (UFSC) apresenta características estratégicas no que se refere à gestão de pessoas, a partir da percepção dos gestores responsáveis por tal área. Em termos metodológicos, este estudo caracteriza-se como qualitativo e utilizou, como técnicas de coleta de dados, a entrevista semiestruturada com quatro gestores da área. Constatou-se que a UFSC apresenta ações relacionadas à gestão estratégica de pessoas, porém todos os entrevistados ressaltaram que ainda é necessária evolução, destacando as atividades de capacitação já implementadas na instituição e a preocupação da administração central em caminhar em direção ao desenvolvimento estratégico de pessoas.
Fatores que influenciam as atitudes pró-ambientais dos estudantes de negócio
Authors: Nascimento Eduardo Mendes , Andrade Poliana Moreira de
Published: October 2018

O presente estudo tem por objetivo identificar as variáveis que influenciam a consciência ecológica dos estudantes na área de negócios em duas instituições educacionais. Para tanto, foi realizada uma pesquisa descritiva, utilizando-se um levantamento como estratégia para coleta de dados, com abordagem quantitativa para sua análise. Esse levantamento foi feito com 257 graduandos que responderam a um questionário contendo 35 questões. O questionário foi estruturado em duas partes, sendo a primeira constituída de variáveis que tiveram o objetivo de descrever a amostra, e a segunda de levantar o grau de consciência ambiental apresentado pelos respondentes. Os dados obtidos foram tabulados em pacote estatístico (Stata), no qual foram realizadas análises estatísticas descritivas. Assim, foram identificadas as variáveis que influenciam a consciência ecológica dos graduandos dos citados cursos, bem como quais variáveis se apresentam com mais ou menos relevâncias nas atitudes ambientalmente desejadas em relação ao meio ambiente. Os resultados demonstraram que a família é estatisticamente significativa na aquisição de hábitos ambientalmente corretos, além da idade, do curso e da instituição que frequenta, bem como ter filhos ou não. Além desses fatores, a autoimagem em relação à prática de atitudes que minimizem a dilapidação do meio ambiente se mostrou relevante para que os indivíduos tenham atitudes ambientalmente corretas.
Los consorcios y la problemática del personal a su servicio
Authors: Quesada Lumbreras Javier Eduardo
Published: October 2018

En este trabajo voy a analizar el régimen jurídico de los consorcios. Una figura que, en los últimos años, ha experimentado una atención normativa sin precedentes. Su régimen orgánico, funcional, presupuestario y de gestión de personal se ha intensificado notablemente. El objetivo de las últimas reformas ha sido muy loable y comprensible tras todos estos años de crisis económica que seguimos padeciendo. Pero creo que las medidas normativas que han sido adoptadas se han cebado en exceso en torno a esta figura que no hace sino dar cumplimiento a uno de los principios más esenciales de nuestro Estado de Derecho. Y no sólo eso sino que además, en la materia que centraré especialmente mi atención, se ha generado más incertidumbre que seguridad y certeza jurídica a nuestros operadores jurídicos.