bluuebunny/crossref_metadata_2025 huggingface dataset:
Therapeutic Landscape as Value Added in the Structure of
the Destination-Specific Therapeutic Tourism Product
Authors: Dryglas Diana , Salamaga Marcin
Published: November 2023

The aim of the paper is to describe how therapeutic landscape creates value added for tourists in spa resorts. Survey data were collected from 184 tourists to Swoszowice spa resort in Poland using a self-administered questionnaire. The results indicated that the way the therapeutic landscape creates value added for tourists differs concerning socio-demographic, behavioural and psychographic factors. The conclusions have important implications for scholars, allowing them to understand the importance of the therapeutic landscape and its determinants for tourists. Knowledge of how tourists assess landscape aesthetics, which constitute value added in the structure of the destination-specific therapeutic tourism product (DSTTP), is essential for local government entities and managers of treatment enterprises to develop and manage a therapeutic product that meets the needs of their customers. The present paper fills the gap in the subject literature, which lacks studies assessing the therapeutic landscape as one of the elements in the structure of DSTTP.
Aplicaciones Móviles para Calcular Volumen del Agua Recolectada por Atrapanieblas, Zona 9 de Lima-Perú
Authors: Manrique Suarez Luis Humberto , Ochoa Sotomayor Nancy Alejandra , Salazar Robles Héctor Gavino , Flores Masías Edward José
Published: November 2023

En la zona 9 de Lima Metropolitana, en el distrito de Pachacámac el 40.7 %, Lurín 19.7 %, Villa María del Triunfo 14.7 % y Villa El Salvador con 3.7 % de las viviendas carecen de agua de la red pública. El objetivo de nuestro trabajo de investigación fue calcular el volumen del agua recolectada por atrapanieblas mediante aplicaciones móviles como medio de mitigar la escasez de agua; además determinar el mejor modelo entre  cilíndrico, semiesférico y semielíptico; ahorro generado mediante el autoconsumo de agua obtenida y como mejoró la visión ornamental en la zona 9 de Lima Metropolitana mediante aplicaciones móviles; la investigación es no experimental, con enfoque cuantitativo de tipo descriptivo – explicativo, se empleó el método analítico-sintético; del universo de  viviendas de la zona 9, se determinó el tamaño de muestra con el método del coeficiente de variación,  (n= 167), el instrumento utilizado fue la encuesta; luego de la evaluación del volumen de agua, utilizando la aplicación móvil geogebra de los tres modelos de atrapanieblas resulta más eficiente el modelo semielíptico por captar mayor volumen mensual equivalente a 7600 litros al mes en comparación a los otros dos modelos que obtienen un volumen de 3452 litros al mes. De acuerdo al volumen captado por el modelo semielíptico y relacionando con los datos de la tabla 8 que indica la cantidad y frecuencia de agua comprada se evidencia que a las familias les resulta ventajoso instalar atrapanieblas porque con la captación de agua de obtendrían ahorros significativos en bien de su economía. Asimismo, al instalarse los atrapanieblas de diferentes diseños y colores se tendría una mejor visión panorámica, convirtiendo a la zona en un inmenso mural, contribuyendo a la atracción turística como parte de un propósito de crecimiento colectivo y prosperidad, en base a la promoción de un sentido de orgullo y pertinencia.
Influencia de la Educación en Liderazgo en Medio de los Procesos de Enseñanza- Aprendizaje en el Aula
Authors: Olmos Jiménez Diana Judith , Orozco Londoño Amalia Del Carmen , Yaquero Puertas Liliana Patricia , Osorio Guevara Héctor Fabio , Pérez Pertúz Johemir Jesus
Published: November 2023

En el presente artículo se analiza la influencia de la educación en liderazgo en los procesos de enseñanza y aprendizaje en el aula de las instituciones educativas públicas de la región Andina de Colombia. La metodología usada fue de enfoque cualitativo, de manera inductiva y descriptiva. Los datos obtenidos se recolectaron a través de entrevista semiestructurada compuesta por once preguntas a estudiantes y profesores de Educación Media, pertenecientes a las instituciones educativas públicas de la zona en cuestión. A partir de las experiencias los docentes y estudiantes forman una definición de liderazgo, identificando cuáles son sus características y como esto repercute en los procesos de enseñanza y aprendizaje. Se identifica que el liderazgo en educación es transversal en todas las asignaturas y que no es meramente un cumplimiento de deberes académicos, sino que incluye el desarrollo de las capacidades personales.
Impacto de la investigación en Comunicación: caso Universidad Nacional de Chimborazo del Ecuador
Authors: Zavala Enriquez Jenny , Larrea Naranjo Carlos , Ruales Parreño Ramiro Geovanny , Pillajo Borja Hernán Patricio
Published: November 2023

La investigación es en un camino para el desarrollo. En el caso de la academia es un parámetro para medir la gestión de los docentes – investigadores. Por eso, las universidades y gobiernos están centrados en fomentar la creación de artículos científicos y obras de relevancia que contribuyan a subsanar vacíos de conocimiento, generación de proyectos o soluciones para diversos problemas. Por ello, es necesario analizar la producción científica que generan las universidades, en ciencias sociales, particularmente en comunicación; pues esta área es transversal en la sociedad. A través de una investigación mixta, se analiza el caso de la Carrera de Comunicación de la Universidad Nacional de Chimborazo del Ecuador, con el fin de identificar: nivel cuantitativo y cualitativo de la producción científica y su crecimiento acorde a las cifras mundiales. También, se evidencia que la investigación en comunicación aún no ha superado la barrera de lo regional. En cuanto a los campos de investigación abordados, las TIC´S es un área por profundizar, pues en la actualidad es indispensable para la sociedad. De esta forma, se obtiene un análisis sobre la evolución de la investigación en comunicación y las tendencias que debe seguir para conseguir un impacto en la ciencia mundial.
The Travails of Prosecuting Serving Heads of State before the ICC: The Case of Omar Al Bashir and Vladimir Putin
Authors: Masumbe Paul S.
Published: November 2023

Even though the International Criminal Court (ICC) is more than two decades after the Rome Statute was ratified by state parties, prosecuting serving heads of state before its jurisdiction has been a nightmare, albeit the Court does not recognise immunities before its jurisdiction. Accordingly, waiving the personal immunity of serving heads of state has been one of the greatest contentions before the Court as seen in the Al Bashir case. While cooperation in matters of arrest and surrender to the Court remains another major concern, the fact that the treaty creating the Rome Statute is primarily binding only on state parties is another obstacle, since consent is required from non-state parties before any prosecution. This article argues that prosecuting President Putin will result in a debacle just like his counterpart Al Bashir given that the issue of immunities and cooperation is still a major concern. Unfortunately, until all states become parties to the Rome Statute, this issue of state cooperation with the Court is still far from over. Consequently, all states are urged to become party to the Rome Statute to minimise the travails of prosecuting serving heads- of-state.

Keywords: Rome Statute, immunities, cooperation in matters of arrest and surrender, serving heads of state, Vladimir Putin, Omar Al Bashir.
Extended Habitability of Exoplanets Due to Subglacial Water
Authors: Wandel Amri
Published: November 2023

Considering subglacial liquid water, a significant extension of the classical Habitable Zone is obtained. Elaborating on the model of Wandel it is shown how an atmosphere and liquid water could survive on tidally locked planets closely orbiting an M-dwarf host, extending the Habitable Zone boundary inwards. In addition, subglacial liquid water could extend the Habitable Zone beyond the outer boundary of the conservative Habitable Zone as well. These two results enhance the circumstellar region with a potential for liquid water well beyond the conservative boundaries of the classical Habitable Zone. It is argued that the probable recent JWST detection of atmospheric water vapor on the rocky Earth-sized exoplanet GJ 486 b, along with earlier detections of water on other planets orbiting M-dwarf stars, gives an empirical answer to the much-argued question of whether such planets can support liquid water, organic chemistry, and eventually life. It is shown how water on terrestrial planets closely orbiting M-dwarf stars may sustain in a subglacial melting layer. Finally, the model is applied to a few exoplanets demonstrating how water detection may constrain their atmospheric properties.
Polarized Anisotropic Synchrotron Emission and Absorption and Its Application to Black Hole Imaging
Authors: Galishnikova Alisa , Philippov Alexander , Quataert Eliot
Published: November 2023

Low-collisionality plasma in a magnetic field generically develops anisotropy in its distribution function with respect to the magnetic field direction. Motivated by the application to radiation from accretion flows and jets, we explore the effect of temperature anisotropy on synchrotron emission. We derive analytically and provide numerical fits for the polarized synchrotron emission and absorption coefficients for a relativistic bi-Maxwellian plasma (we do not consider Faraday conversion/rotation). Temperature anisotropy can significantly change how the synchrotron emission and absorption coefficients depend on observing angle with respect to the magnetic field. The emitted linear polarization fraction does not depend strongly on anisotropy, while the emitted circular polarization does. We apply our results to black hole imaging of Sgr A* and M87* by ray tracing a GRMHD simulation and assuming that the plasma temperature anisotropy is set by the thresholds of kinetic-scale anisotropy-driven instabilities. We find that the azimuthal asymmetry of the 230 GHz images can change by up to a factor of 3, accentuating (T
⊥ > T
∥) or counteracting (T
⊥ < T
∥) the image asymmetry produced by Doppler beaming. This can change the physical inferences from observations relative to models with an isotropic distribution function, e.g., by allowing for larger inclination between the line of sight and spin direction in Sgr A*. The observed image diameter and the size of the black hole shadow can also vary significantly due to plasma temperature anisotropy. We describe how the anisotropy of the plasma can affect future multifrequency and photon ring observations. We also calculate kinetic anisotropy-driven instabilities (mirror, whistler, and firehose) for relativistically hot plasmas.
On the Escape of Low-frequency Waves from Magnetospheres of Neutron Stars
Authors: Golbraikh Ephim , Lyubarsky Yuri
Published: November 2023

We study the nonlinear decay of the fast magnetosonic (fms) into the Alfvén waves in relativistic force-free magnetohydrodynamics. The work has been motivated by models of pulsar radio emission and fast radio bursts (FRBs), in which the emission is generated in neutron star magnetospheres at conditions when not only the Larmor but also the plasma frequencies significantly exceed the radiation frequency. The decay process places limits on the source luminosity in these models. We estimated the decay rate and showed that the phase volume of Alfvén waves available for the decay of an fms wave is infinite. Therefore, the energy of fms waves could be completely transferred to the small-scale Alfvén waves not via a cascade, as in the Kolmogorov turbulence, but directly. Our results explain the anomalously low radio efficiency of the Crab pulsar and show that FRBs could not be produced well within magnetar magnetospheres.
Bridging between Type IIb and Ib Supernovae: SN IIb 2022crv with a Very Thin Hydrogen Envelope
Authors: Gangopadhyay Anjasha , Maeda Keiichi , Singh Avinash , A. J. Nayana , Nakaoka Tatsuya , Kawabata Koji S. , Taguchi Kenta , Singh Mridweeka , Chandra Poonam , Ryder Stuart D. , Dastidar Raya , Yamanaka Masayuki , Kawabata Miho , Alsaberi Rami Z. E. , Dukiya Naveen , Teja Rishabh Singh , Ailawadhi Bhavya , Dutta Anirban , Sahu D. K. , Moriya Takashi J. , Misra Kuntal , Tanaka Masaomi , Chevalier Roger , Tominaga Nozomu , Uno Kohki , Imazawa Ryo , Hamada Taisei , Hori Tomoya , Isogai Keisuke
Published: November 2023

We present optical, near-infrared, and radio observations of supernova (SN) SN IIb 2022crv. We show that it retained a very thin H envelope and transitioned from an SN IIb to an SN Ib; prominent Hα seen in the pre-maximum phase diminishes toward the post-maximum phase, while He i lines show increasing strength. SYNAPPS modeling of the early spectra of SN 2022crv suggests that the absorption feature at 6200 Å is explained by a substantial contribution of Hα together with Si ii, as is also supported by the velocity evolution of Hα. The light-curve evolution is consistent with the canonical stripped-envelope SN subclass but among the slowest. The light curve lacks the initial cooling phase and shows a bright main peak (peak M

V
= −17.82 ± 0.17 mag), mostly driven by radioactive decay of 56Ni. The light-curve analysis suggests a thin outer H envelope (M
env ∼ 0.05 M
⊙) and a compact progenitor (R
env ∼ 3 R
⊙). An interaction-powered synchrotron self-absorption model can reproduce the radio light curves with a mean shock velocity of 0.1c. The mass-loss rate is estimated to be in the range of (1.9−2.8) × 10−5
M
⊙ yr−1 for an assumed wind velocity of 1000 km s−1, which is on the high end in comparison with other compact SNe IIb/Ib. SN 2022crv fills a previously unoccupied parameter space of a very compact progenitor, representing a beautiful continuity between the compact and extended progenitor scenario of SNe IIb/Ib.
MHD in a Cylindrical Shearing Box. II. Intermittent Bursts and Substructures in MRI Turbulence
Authors: Suzuki Takeru K.
Published: November 2023

By performing ideal magnetohydrodynamical (MHD) simulations with weak vertical magnetic fields in unstratified cylindrical shearing boxes with modified boundary treatment, we investigate MHD turbulence excited by magnetorotational instability. The cylindrical simulation exhibits extremely large temporal variation in the magnetic activity compared with the simulation in a normal Cartesian shearing box, although the time-averaged field strengths are comparable in the cylindrical and Cartesian setups. Detailed analysis of the terms describing magnetic energy evolution with “triangle diagrams” surprisingly reveals that in the cylindrical simulation the compression of toroidal magnetic field is unexpectedly as important as the winding due to differential rotation in amplifying magnetic fields and triggering intermittent magnetic bursts, which are not seen in the Cartesian simulation. The importance of the compressible amplification is also true for a cylindrical simulation with tiny curvature; the evolution of magnetic fields in the nearly Cartesian shearing box simulation is fundamentally different from that in the exact Cartesian counterpart. The radial gradient of epicyclic frequency, κ, which cannot be considered in the normal Cartesian shearing box model, is the cause of this fundamental difference. An additional consequence of the spatial variation of κ is continuous and ubiquitous formation of narrow high-density (low-density) and weak-field (strong-field) localized structures; seeds of these ring gap structures are created by the compressible effect and subsequently amplified and maintained under the marginally unstable condition regarding “viscous-type” instability.
Theory of Magnetic Switchbacks Fully Supported by Parker Solar Probe Observations
Authors: Toth Gabor , Velli Marco , van der Holst Bart
Published: November 2023

Magnetic switchbacks are rapid high-amplitude reversals of the radial magnetic field in the solar wind that do not involve a heliospheric current sheet crossing. First seen sporadically in the 1970s in Mariner and Helios data, switchbacks were later observed by the Ulysses spacecraft beyond 1 au and have been recently discovered to be a typical component of solar wind fluctuations in the inner heliosphere by the Parker Solar Probe spacecraft. While switchbacks are now well understood to be spherically polarized Alfvén waves thanks to Parker Solar Probe observations, their formation has been an intriguing and unsolved puzzle. Here we provide a simple yet predictive theory for the formation of these magnetic reversals: the switchbacks are produced by the distortion and twisting of circularly polarized Alfvén waves by a transversely varying radial wave propagation velocity. We provide an analytic expression for the magnetic field variation, establish the necessary and sufficient conditions for the formation of switchbacks, and show that the proposed mechanism works in a realistic solar wind scenario. We also show that the theoretical predictions are in excellent agreement with observations, and the high-amplitude radial oscillations are strongly correlated with the shear of the wave propagation speed. The correlation coefficient is around 0.3–0.5 for both encounter 1 and encounter 12. The probability of this being a lucky coincidence is essentially zero with p-values below 0.1%.
On the Existence of Subsonic Solitary Waves Associated with Reconnection Jets in Earth’s Magnetotail
Authors: Singh Kuldeep , Varghese Steffy Sara , Verheest Frank , Kourakis Ioannis
Published: November 2023

The Magnetospheric Multiscale Spacecraft (MMS) has detected the signature of electrostatic solitary waves (ESWs) occurring in the reconnection jet site of the Earth’s magnetotail (Liu et al.). These observations have motivated us to explore the mechanism underlying the formation of fast- and slow-mode ion-acoustic solitary waves in the magnetotail region. To this end, we have formulated a three-component magnetized plasma model consisting of nonthermal electrons and two cold ion beams streaming parallel and antiparallel to the magnetic field, respectively. In this work, we have examined the existence conditions for ion-acoustic subsonic waves in a suprathermal space plasma comprising two counterstreaming (drifting) ion beams interacting with a suprathermal electron background. An exact (nonperturbative) nonlinear technique has been adopted to examine the role of the beam velocity and the spectral index on the evolution of subsonic waves. Linear analysis reveals that subsonic waves are unstable when the beam velocity is lower than a threshold value; hence in this regime, only conventional supersonic (fast) waves are formed. On the other hand, when the beam velocity exceeds the threshold, either supersonic or subsonic waves may exist. The combined impact of the beam velocity and electron superthermality on the characteristics of subsonic solitary waves has been analyzed. Our results are shown to be in good agreement with observations of slow ESWs by the MMS spacecraft. Our findings will help to unfold the so-far unexplored dynamical characteristics of subsonic waves that may occur in the reconnection site of Earth’s magnetotail.
L’écoute clinique de la parentalité : un espace pour symboliser la dyade parent-enfant
Authors: de Sousa e Silva Mariana , Tarouquela Brasil Katia , Lazzarini Éliana Rigotto , Viçosa Cardoso Tanize
Published: November 2023

La parentalité impose au sujet un travail psychique intense qui s’appuie sur des aspects narcissiques, archaïques, sur l’histoire de la filiation et de la transmission psychique. La parentalité est, avant tout, liée à un processus qui comporte des risques psychiques particuliers face aux événements de vie. Identifier ces enjeux dans la relation parent-enfant et comprendre ce qui est sollicité pour le sujet face à des événements nécessite de remodeler les alliances et de trouver un nouvel équilibre psychique. Dans le cadre d’une recherche clinique, les auteures, impliquées dans un dispositif d’écoute psychanalytique de la parentalité, proposent une discussion quant aux repères cliniques des enjeux qui sous-tendent la relation parent-enfant. Ce questionnement est discuté par deux vignettes cliniques, celle de Maria qui, après son accouchement, expérimente des vécus corporels primitifs projetés sur son bébé et celle de Camila, qui commence son analyse après la tentative de suicide de sa fille. Dans l’ensemble de ces vignettes, on observe une réorganisation de la dynamique psychique et une possibilité de symboliser davantage les modes d’alliance de la dyade parent-enfant.
Séparation conjugale, clivage parental et construction identitaire de l’enfant
Authors: Andrades Nicolas
Published: November 2023

Les espaces de rencontre enfants/parents (ou erep ) sont des lieux dédiés aux rencontres d’un parent et de son ou ses enfants, dans un contexte de conflit conjugal rendant impossible l’exercice de droits de visite classiques. Ils peuvent être la scène de vécus difficiles pour les enfants concernés. Cet article propose, à travers le récit détaillé puis une lecture interprétative d’une vignette clinique concernant un enfant de 6 ans venant rencontrer son père en erep , la mise en évidence, à l’aide d’outils théoriques issus de la littérature psychanalytique, des conséquences négatives du clivage des discours parentaux sur le travail d’élaboration identitaire de l’enfant, en lien avec sa filiation. Il est également question du rôle actif que peuvent jouer les professionnels de l’espace de rencontre dans la réduction de tels clivages, défendant ainsi l’intérêt supérieur de l’enfant.
« Effluve de peau » : l’odyssée d’un corps en quête de reconnaissance. Le phénomène de l’incurie corporelle chez les adolescents psychotiques
Authors: Taglialatela Carla
Published: November 2023

Nous proposons de considérer l’incurie corporelle chez l’adolescent psychotique comme la manifestation d’une tentative, de la part du sujet, d’ habiter le monde et d’être reconnu par lui. Ne mettant pas en question les acquis sur l’incurie qui la démarquent par les notions d’abandon, de négligence et d’isolement, nous proposons d’explorer de nouveaux horizons de signification du phénomène et cela par une lecture anthropo-phénoménologique de la question.
Que nous disent les statistiques ?
Authors: Pfefferkorn Roland
Published: November 2023

Trop souvent ignorées, les femmes seules avec des enfants, qui représentent la majorité des familles monoparentales, cumulent les difficultés.
Prendre un enfant par la main
Authors: Robault Adélaïde
Published: November 2023

En Seine-Saint-Denis, l’association l’École enchantiée accompagne les enfants dans leur scolarité. Une mission qui va de pair avec l’accès aux droits des familles précaires.
Needs Assessment Survey for Stroke Care Core Competency-Based Training for Neuroscience Nurses
Authors: Kang Hana , Roh Young Sook
Published: November 2023

Background:

Assessment of stroke care core competency for neuroscience nurses is crucial for developing training programs to improve the quality of care for patients who have a stroke. The goal of this study was to determine the priorities for competency-based training using an importance–performance analysis of stroke care core competency among neuroscience nurses.

Method:

A cross-sectional descriptive survey was conducted using a convenience sample of 154 neuroscience nurses. Differences in importance and performance scores were analyzed with paired
t
tests. The training priority was determined using the importance–performance matrix.

Results:

The overall performance score was significantly lower than the importance score. The highest priority areas of training were (a) principles of stroke care and (b) cardiovascular and respiratory effects.

Conclusion:

Competency-based continuing education is needed in implementing stroke best practices for neuroscience nurses to achieve optimal competency.

[
J Contin Educ Nurs.
2024;55(2):63–68.]
Microscopic mechanism of subgrade vibration compaction based on discrete element method
Authors: Gao Xin , Liu Hao , Fang Zhou , Zhang Yang
Published: November 2023

The discrete element is an important tool for vibration compaction simulation from the microscopic viewpoint. The irregular particle model was established by the disc filling method, and the linear contact model with anti-rolling was selected to reflect the contact characteristics between the particles, so as to establish the simulation model of subgrade vibratory compaction. Based on this model, the stress characteristics of the area below the center of the vibrating wheel and the surface area of the soil were studied, and the principle of vibratory compaction was discussed. The results show that the distribution of vertical stresses below the center of drum basically presents a decreasing trend in the depth range during vibration, with the stress amplitude of the lower structure increasing and the stress magnitude of the upper structure decreasing. The distribution of horizontal stresses in the area below the center of the vibrating wheel is similar to the stress distribution in the splitting test. The soil at the surface has an obvious pushing and squeezing effect, and the transmission distance of horizontal stresses is larger than that of vertical stresses. The soil at the surface is pushed and the horizontal stresses are transmitted at a greater distance than the vertical stresses, which, together with a certain degree of shear effect, causes a certain uplift deformation of the soil around the vibrating wheel. In general, the vibration compaction process is relatively consistent with the theory of repeated loading and the theory of alternating shear strain.
Robust estimation for varying-coefficient partially nonlinear model with nonignorable missing response
Authors: Xiao Yanting , Shi Yifan
Published: November 2023

In this paper, we studied the robust estimation for the varying-coefficient partially nonlinear model based on modal regression with nonignorable missing response. First, an instrumental variable was used to handle the identifiability issue of parameters in the propensity score function, and a generalized method of moment was combined to obtain the consistent estimators. Second, inverse probability weighting and modal regression were adopted to construct the estimators of parameters and coefficient function in the model. Under some mild conditions, the asymptotic properties of the resulting estimators were established. Furthermore, simulation studies and a real example were carried out to illustrate the effectiveness of our proposed estimation procedures.
Podzemno raztekanje vode iz ponora Tržiščice (JV Slovenija)
Authors: Kogovšek Janja , Petrič Metka
Published: November 2023

Sledilni poskus z injiciranjem v ponor Tržiščice (JV Slovenija) je v hidroloških pogojih upadanja pretokov od srednjih do nizkih voda pokazal koncentriran odtok v smeri Tominčevega studenca ter Javornikovega in Debeljakovega izvira ob Krki pri Dvoru. Navidezne hitrosti pretakanja so bile med 2,4 in 4,6 cm/s, povrnjena količina uranina v teh izvirih pa je bila ocenjena na 2/3 injicirane količine. Navidezna hitrost pretakanja v smeri Podpeške jame, kjer se je sledilo pojavilo manj izrazito in šele po izdatnejših padavinah, ki so nastopile po dveh mesecih stalnega upadanja pretokov, je bila 0,1 cm/s. Ugotovitve skupaj z rezultati starejših sledenj kažejo na značilno odvisnost raztekanja vode iz Tržiščice od hidroloških razmer. A tracing test with injection of uranine in the sinking stream Tržiščica (SE Slovenia) was carried out at the hydrological conditions of recession from medium to low waters. Concentrated flow towards the springs Tominčev studenec, Javornikov izvir and Debeljakov izvir near the village Dvor in the Krka valley was proved. Apparent flow velocities between 2.4 and 4.6 cm/s were obtained, and the share of recovered tracer was estimated to 2/3 of the injected amount. In the Podpeška jama cave the tracer in lower concentrations was detected only after heavy rain occurred after two months of low water. The apparent flow velocity of 0.1 cm/s was calculated. Obtained results, together with the outcomes of the previous tracing tests, indicate that hydrological conditions significantly influence the underground water flow from the Tržiščica sinking stream.
The Role of Sarvak Formation in Supplying Pol-e Dokhtar Town (Iran) with Drinking Water
Authors: Ahmadipour Mohamad Reza
Published: November 2023

Formacija Sarvak je najbolj zakrasela formacija v skupini Bagestan, SZ od mesta Pol-e Dokhtar. Njeno južno krilo je zakraselo in najpomembnejše za talno vodo. Za oskrbo s pitno vodo mesta Pol-e Dokhtar, so bili izvrtani trije vodnjaki. Opravljen je bil črpalni (72 ur). Analize kisika-18 in devterija kažejo na meteorni izvor vode. Voda iz vodnjaka W1 ima minimalno, iz W3 pa maksimalno koncentracijo tricija, kar kaže na različen rezidenčni čas, kemične analize pa, da gre za vode tipa Ca>Mg>Na in HCO3 >SO4 >Cl. Med samim vrtanjem so imeli vzorci vode relativno veliko količino NO3 (27 mg/l), ki se je, zaradi zavarovanja področja pred kmetijsko dejavnostjo, znižala. Mesto Pol-e Dokhtar, ki je imelo resne težave z oskrbo s pitno vodo že izpred časov islamske republike, teh zdaj nima več, zahvaljujoč predstavljeni raziskavi.The Sarvak formation is the most karstified formation of the Bageston group, NW from town Pol-e Dokhtar. Its southern limb is karstified and the most important for the ground water. Three wells were drilled for supplying the drinking water to Pol-e Dokhtar. The pumping test (72 hours) was carried out. Analyses of oxygen-18 and deuterium indicated that the water is of meteoric origin. Water from the well1 has the minimal and from the well3 maximal concentrations of tritium which indicate different residence time. Chemical analyses show that the water is of Ca>Mg>Na and HCO3>SO4>Cl type. During the drilling water samples had relatively high NO3 (27 mg/l), which was reduced due to the protection of the area from agricultural activities. Due to this study, the town of Pol-e Dokhtar, which was facing serious problem of drinking water since before the Islamic Republic of Iran, has been solved.
Treatises About the Subterranean World in Ljubljana Between 1678 and 1773
Authors: Južnič Stanislav
Published: November 2023

Popisali smo knjige, razprave in rokopise o podzemeljskih in kraških pojavih, ki so bile na voljo v Ljubljani v času delovanja jezuitskega kolegija. Preučili smo Mayrjev prodajni katalog iz leta 1678. Pregledali smo knjige, ki so jih nabavljali za jezuitsko in druge knjižnice v Ljubljani. Posebno pozornost smo posvetili doslej neraziskanim objavljenim delom in rokopisom ljubljanskih jezuitov. Pokazali smo, kako je v Ljubljani nakopičeno znanje pripomoglo k nastanku pionirskih del modernega krasoslovja v zadnji četrtini osemnajstega stoletja.We researched the books, papers, and manuscripts about the subterranean and karst phenomena available in Ljubljana in the time of Jesuit college. We used the data from Mayr's book catalogue of 1678. We analyzed the books in the Jesuit and other Ljubljanese libraries. For the first time in historiography the special concern was put on published works and manuscripts of the Ljubljanese Jesuits. We described how the knowledge accumulated in Ljubljana paved the way for pioneering karstology research in the last quarter of the 18th century.
Some 19th Century Visitors to Caves in Peninsular Malaysia
Authors: Price Liz
Published: November 2023

Človek je poznal jame v Maleziji že od predzgodovinskih časov, ko jih je uporabljal kot zatočišča, taborišča ali skrivališča. Najstarejša taka sled s polotoške Malezije je človeško okostje, staro 11.000 let. Prvi zapisi o obiski teh jam pa izvirajo šele iz 19. stoletja, ko so jih obiskovali predvsem Evropejci za zabavo, iz vedoželjnosti ali zaradi raziskovanja. Z raziskavami so v glavnem pričeli britanski kolonialni častniki, nastanjeni v Malaji, v 80-tih letih 19. stoletja. Leta 1878 so "odkrili" jame Batu in z njimi seznanili Evropejce. V prispevku so našteti nekateri izmed teh obiskovalcev ter so opisane zgodnje raziskave.Malaysian caves have been known to man since prehistoric times, when they were used as shelters, campsites or places of refuge. The oldest remains found in Peninsular Malaysia are a human skeleton dated at 11.000 years old. But it wasnot until the 19th century that records appear of caves being visited, generally by European visitors for recreation, curiosity or research. Research generally began in the 1880's, mainly by British colonial officers stationed in Malaya. The caves at Batu Caves were ˝discovered˝ and made known to Europeans in 1878. This article lists some of the visitors and describes some of the early research.
Utilization of Data Science Analytics on Mobile Commerce Applications Marketing Strategies: An Example of the Influence of Personalized Offers on the Usage Intentions of Saudi Consumers
Authors: Aljohani Nasser
Published: November 2023

The integration of data science plays a vital role in the progression of mobile applications, as it enhances their overall effectiveness and provides users with more benefits. Data science tools have the potential to assist organizations in enhancing their brand marketing endeavors and providing personalized offers, therefore contributing to the overall improvement of consumer acquisition. Consequently, the primary objective of this research was to investigate the influence of the personalized offers aspect on users of mobile commerce applications in Saudi Arabia, in addition to the core elements of the technology acceptance model (TAM). The result of this study indicates that perceived usefulness exhibits the greatest degree of impact in influencing customer attitudes toward usage, with personalized offers following closely. The research further reveals that personalized offers exert a substantial favorable influence on customers’ attitudes towards their use. Additionally, the research reveals that personalized offers significantly influence individuals’ behavioral intentions concerning the use of m-commerce applications. This research offers significant insights that might inform future academic research in the field. Moreover, it provides app developers and enterprises with novel knowledge and comprehension to devise tactics that enhance the ongoing advancement of mobile commerce applications.
Data-Driven Insights in Higher Education: Exploring the Synergy of Big Data Analytics and Mobile Applications
Authors: Ishamuddin Mustapha  , Vichayanan Rattanawiboonsom  , Ruankwan Intanon
Published: November 2023

This study explores the potential for transformation that may be achieved via the use of big data analytics and mobile apps in the context of higher education, specifically emphasizing the role of data-driven decision-making. Within the contemporary educational landscape, characterized by the increasing impact of digital technology and mobile devices, institutions of higher education are actively investigating innovative strategies. That enhances effectiveness, customizes learning experiences to suit individual students, and develops overall student accomplishments. The main objective of this research is to examine the effects of incorporating big data analytics and mobile applications into the decision-making capacities of higher education establishments. The PRISMA Statement was used to guide the selection and exclusion of records using the RStudio Biblioshiny approach for data analysis. A comprehensive review of the existing scholarly works, identification of groupings, and study of citation trends within the field. The results and findings illustrate the inherent importance of “big data,” “cloud computing,” “mobile computing,” and “higher education” in the field of research, underscoring their crucial role in data-driven decision-making. Furthermore, the study underscores the significant impact of contemporary technology on administrative processes, personalized learning, and scholastic attainment. This research provides a great addition to the academic field by presenting insightful findings on the substantial influence of big data analytics and mobile applications on the evolution of higher education. This study emphasizes the need to adopt data-driven insights to successfully navigate the ever-changing landscape of higher education.
Stress, Anxiety, and Depression among the Health-care Workforce during the COVID-19 Pandemic: A Cross-Sectional Study
Authors: Khot Pawan V , Patil Vishal Ganpati , Ainapur Krutika , Harshe Sneha , Karia Sagar , Sousa Avinash De , Harshe Devavrat
Published: November 2023

Aim:

The study was aimed at calculating the levels of stress, anxiety, and depression among medical and health-care workers working in hospitals that catered to COVID-19 patients.

Methodology:

A total of 471 healthcare and medical personnel filled up an online socio-demographic pro forma and answered the Depression, Anxiety, and Stress scale. The data were analyzed using descriptive statistics and Chi-square test where appropriate.

Results:

The sample consisted of medical personnel and nurses. Majority were married and male. The levels of anxiety and stress were reported to be higher in males while depression was reported higher in females. Being unmarried and not having children were factors that showed higher depression levels while no socio-demographic factors showed a trend with anxiety and stress.

Conclusion:

Depression, anxiety, and stress are common in medical personnel and health-care workers working in the COVID-19 pandemic. Sound mental health interventions for these workers and large studies in specific populations are needed to corroborate these findings.
Diagnostic and Statistical Manual of Mental Disorders Text Revision - 5th Edition: What’s Changed from Diagnostic and Statistical Manual of Mental Disorders - 5th Edition? A Detailed Review
Authors: Chakrabarty Arindam , Javadekar Archana , Chakrabarty Ashima Datey
Published: November 2023

The American Psychiatric Association published the text revision (DSM-5-TR) to the Diagnostic and Statistical Manual (DSM-5) in March 2022. This is an update to the 2013 publication of the original manual. The DSM-5-TR features the most current text updates based on the current scientific literature with the goal of increasing the accuracy and consistency with which clinicians make a psychiatric diagnosis (1). The following article details the changes that were made in the DSM5-TR.
A study of adverse childhood experiences and psychopathology of imprisoned sexual offenders at a central prison, Hyderabad, Telangana
Authors: Agnihotri Shruti , Ravirala Anitha , Umashankar M.
Published: November 2023

Introduction:

Sexual offense has been defined as sexual contact with another person (including touching of the sexual organs of another) or touching of another person with one’s sexual organs without that person’s consent. Adverse childhood experiences could lead to health problems, behavioral problems, and psychosocial problems like crimes.

Aims:

The aim is to study adverse childhood experiences and psychopathology of imprisoned sexual offenders.

Materials and Methods:

A sample of 48 sexual offenders from a central prison and after taking informed consent, a semi-structured intake pro forma was used, followed by that adverse childhood experiences–international questionnaire, Mini-international neuropsychiatric interview-7.0.2 were applied.

Results:

It was found that the majority of the offenders had experienced adversities in their childhood, the most common being community violence and physical abuse, emotional neglect. Half of the participants had antisocial personality disorder. A statistically significant relationship was found between adverse childhood experiences score and number of offenses committed (P = 0.002).

Conclusion:

It can be concluded that the presence of adverse childhood experiences could affect physical, mental health in adulthood, and increase crimes.
ADAMTS13 Inhibits H2O2-induced Human Venous Endothelial Cell Injury to Attenuate Deep-Vein Thrombosis by Blocking the p38/ERK Signaling Pathway
Authors: Zheng Guangfeng , Zhang Qiang , Li Chuanyong , Fan Weijian , Pan Zhichang , Zhou Yuting , Chen Yan , Rong Jianjie
Published: November 2023

Deep vein thrombosis (DVT) is a common complication in hematologic malignancies and immunologic disorders. Endothelial cell injury and dysfunction comprise the critical contributor for the development of DVT. A disintegrin and metalloproteinase with thrombospondin motifs 13 (ADAMTS13), a plasma metalloprotease that cleaves von Willebrand factor, acts as a critical regulator in normal hemostasis. This study was aimed to explore the role of ADAMTS13 in endothelial cell injury during DVT and the possible mechanism. First, human umbilical vein endothelial cells (HUVECs) were exposed to hydrogen peroxide (H2O2). Then, the mRNA and protein expressions of ADAMTS13 were evaluated with the reverse transcription-quantitative polymerase chain reaction and western blot. After treatment with recombinant ADAMTS13 (rADAMTS13; rA13), the viability and apoptosis of H2O2-induced HUVECs were assessed by cell counting kit-8 assay and terminal-deoxynucleoitidyl transferase-mediated nick end labeling staining. In addition, the levels of prostaglandin F1-alpha, endothelin-1, and reactive oxygen species were detected using the enzyme-linked immunosorbent assay and dichloro-dihydro-fluorescein diacetate assay. The expressions of proteins related to p38/extracellular signal-regulated kinase (ERK) signaling pathway were estimated with the western blot. Then, p79350 (p38 agonist) was used to pretreat cells to analyze the regulatory effects of rA13 on p38/ERK signaling in H2O2-induced HUVEC injury. The results revealed that ADAMTS13 expression was significantly downregulated in H2O2-induced HUVECs. The reduced viability and increased apoptosis of HUVECs induced by H2O2 were revived by ADAMTS13. ADAMTS13 also suppressed the oxidative stress in HUVECs after H2O2 treatment. Besides, ADAMTS13 was found to block p38/ERK signaling pathway, and p79350 reversed the impacts of ADAMTS13 on the damage of HUVECs induced by H2O2. To sum up, ADAMTS13 could alleviate H2O2-induced HUVEC injury through the inhibition of p38/ERK signaling pathway.
Invasive micropapillary carcinoma of ampulla of Vater in a young female with negative lymph nodes: A case report and review of literature
Authors: Elghareeb Manal M. S. , Ali Khadiga Mohamed , Saleh Gehad Ahmad , Halim Amal A. F.
Published: November 2023

Invasive micropapillary carcinoma (IMPC) is an extremely rare and aggressive subtype of adenocarcinoma that was first described in breast cancer. It is characterised by an inside-out growth pattern with frequent lymphatic spread. Only few cases are described in the rare ampullo-pancreatobiliary location. In this case report, the diagnosis was unexpected given the patient’s age and gender, as well as the negative nodal status. Despite the reported aggressive behaviour of this tumour, no optimal treatment strategy for IMPC in the ampulla of Vater has been established. In addition, this variant is not included in the recent WHO of the digestive system.
Comprehensive overview of biomarkers to predict response to immune checkpoint therapy in lung cancer
Authors: Jain Kriti , Mehra Deepa , Ganguly Nirmal Kumar , Rana Rashmi , Ganguly Surajit , Aggarwal Shyam
Published: November 2023

Immune checkpoint (IC) therapy has brought a huge revolution in the field of lung cancer treatment over the past decade. It has also revolutionised treatment paradigm and has tremendously improved patient prognosis. IC inhibitors (ICIs) targeting Programmed Cell Death Protein 1/Programmed cell death Ligand 1 (PD1/PD-L1) have shown remarkable success and are now being used as first-line therapies in metastatic disease, adjuvant therapy following surgical resection and chemotherapy in resectable disease. Despite this remarkable success, only a subset of patients obtains complete benefit and most patients do not respond or develop progressive disease during treatment. ICIs are relatively expensive and some patients suffer from significant immune-related adverse toxicities. Hence, the identification and discovery of new predictive and prognostic immunotherapy biomarkers remains the present crucial need for patient selection, stratification and also for guiding therapeutic decisions. Currently established biomarkers such as PD-L1 determined by immunohistochemistry and tumour mutation burden determined by next-generation sequencing are non-specific and possess limitations. At present, several other biomarkers using peripheral blood, liquid biopsies along with gene expression signatures, and tumour infiltrating lymphocytes are being researched globally which have demonstrated predictive potential to characterise ICIs responders. In this review, we provide a comprehensive overview of the current biomarkers, highlighting the main clinical challenges and possible novel potential biomarkers to better predict responders to ICIs.
Serum level of interleukin-6, interleukin-17A, and interferon-α in hospitalized COVID-19 patients and their clinical correlation: A hospital-based case–control study from North-East India
Authors: Sharma Suresh , Sarma Paresh Kumar , Talukdar Uddip , Talukdar Ramen , Mishra Nalini , Baruah Dipankar , Sultana Rizwana , Bharali Abhijit
Published: November 2023

BACKGROUND AND OBJECTIVES:

Dysregulation in the homeostasis of the cytokine pool induces severity in COVID-19 disease, which may result in poor clinical outcomes in severely ill patients. The main objective of this study was to evaluate serum interleukin-6 (IL-6), IL-17A, and interferon-α (IFN-α) in hospitalized COVID-19 patients and its association with the disease severity and clinical outcome.

MATERIALS AND METHODS:

Fifty-one hospitalized COVID-19 patients and 30 age- and sex-matched healthy volunteers were enrolled in this study. Serum IL-6, IL-17A, and IFN-α were quantified by enzyme-linked immunosorbent assay-based method. Receiver operating characteristic curve (ROC) analysis was performed for the cytokines.

RESULTS:

Serum IL-6, IL-17A, and IFN-α were significantly higher in COVID-19 patients than healthy control volunteers. Across severity groups, serum IL-6 was significantly higher in the severe group, whereas IFN-α was significantly higher in the mild–moderate group. Serum IL-6 was significantly higher in the deceased group compared to the recovered group. ROC analysis suggests that serum IL-6 can be used as a diagnostic and prognostic marker for severity and clinical outcome, respectively.

CONCLUSION:

Elevated levels of serum IL-6, IL-17A, and IFN-α in COVID-19 patients indicate cytokine dysregulation following severe acute respiratory syndrome coronavirus 2 infection. Elevated serum IL-6 was associated with disease severity and poor clinical outcome. Elevated IFN-α in mild–moderate group compared to the severe group signifies the antiviral effect of IFN-α may help in limiting disease severity in COVID-19 disease. Our data suggest that IL-6 can be used as a diagnostic and prognostic marker for disease severity and clinical outcome, respectively.
The Journey from Past to Present
Authors: Jõgi Larissa
Published: November 2023

The focus of this paper is on the development of andragogy as an academic discipline and andragogy programmes at Tallinn University. It also reviews the development of adult education in Estonia and outlines empirical findings from previous research related to the learning experiences and the professional identity of students and graduates of andragogy programmes. The research questions in this paper are: What are the main developments of adult education and andragogy as an academic discipline? How do andragogy students and graduates understand their learning experience and professional identity? The findings suggest that academic studies and learning experiences enable students to construct a strong learner identity, which impacts the formation of professional identity. The sense of professional identity becomes stronger during the period of academic studies and continues to develop as a self-developmental process with professional, educational, and personal choices.