bluuebunny/crossref_metadata_2025 huggingface dataset:
On DNA code over a finite ring and its related parameters
Authors: P Chella Pandian
Published: December 2023

In this paper, lower bound and upper bound on the covering radius of DNA codes over N with respect to euclidean distance are given. Also determine the covering radius of various Repetition DNA codes, Simplex DNA code Type α and Simplex DNA code Type β and bounds on the covering radius for MacDonald DNA codes of both types over N.
Seiendes, Bewußtsein, Intentionalität
Authors: Antonelli Mauro
Published: December 2023

Was ist Seiendes? Was heißt Bewusstsein? Was bedeutet etwas ‚zum Gegenstand' haben? Diese Fragen stehen im Mittelpunkt von Franz Brentanos Philosophie, die sich als Synthese aus einer Ontologie und Metaphysik aristotelisch-scholastischer Herkunft und einer kartesisch geprägten Bewusstseinsphilosophie entwickelt. Hierbei bildet die Intentionalität des Bewusstseins, die Gerichtetheit mentaler Einstellungen zu den Gegenständen, den Angelpunkt beider Ansätze. Sich mit der Verschränkung von Seiendem, Bewusstsein und Intentionalität beim frühen Franz Brentano auseinanderzusetzen heißt, sich der gemeinsamen Wurzeln von Husselrs Phänomenologie, Heideggers Fundamentaltheologie, Meinongs Gegenstandstheorie, der Gestaltpsychologie sowie der heutigen analytischen Philosophie des Geistes und einiger Ansätze der zeitgenössischen kognitiven Wissenschaft bewusst zu werden.
Nation und Ethos
Authors: Kluxen-Pyta Donate
Published: December 2023

Hat es eine moralische Bedeutung, Deutscher zu sein? Verpflichtet die nationale Identität zu Patriotismus, zu Solidarität gegenüber dem Staat? Solche Fragen zu Nation, Patriotismus und Moral behandelt die Studie systematisch in einer Ethik, die nicht nur das abstrakte Individuum, sondern das menschliche Handeln eingebettet sieht in die konkreten Bedingtheiten eines historisch gebildeten Ethos. Durch die Sozialität und die Geschichtlichkeit des Menschen hängen Ethos und nationale Identität zusammen. Es ist dabei die Verbindung von Schicksal und Sinnperspektive, die als Leistung des Ethos im Begriff der Nation die Annahme der eigenen wie der kollektiven Identität ermöglicht. Mit diesem universalistisch geprüften und kritischen Verständnis von Nation, das auch historisch und philosophiegeschichtlich eingeordnet wird, lässt sich der Patriotismus in seiner Legitimität auszeigen und vom Nationalismus scheiden sowie die Relevanz der nationalen Identität für Individuum, Staat und Gesellschaft verdeutlichen. Als konkretes Beispiel wird das Problem von Nationalbewusstsein und Wertetransfer in der alten wie der neuen Bundesrepublik Deutschland vorgeführt.
Der Ort
Authors: Otto Maria A. C.
Published: December 2023

Im abendländischen Denken hat der „Ort“ seit Aristoteles wenig zu sagen. er wird meist als Position, von einer Ordnung her behandelt, während er in der japanischen Philosophie zwar zentral, aber als eine Art von Nichts gedacht wird. Auch in diesem Buch spielt das Nichts eine Rolle, als leerer Platz, der einem bei Anderem eingeräumt wird. In dieser Konstellation, die den Ort ausmacht, ist das Dasein von sich aus (in Differenz zu Lévinas) Anderem anvertraut, darum auch zu enttäuschen, zu ersetzen. Der Ort, der das Dasein als Hiersein begründet, stellt sich quer zu dessen Zeit: die Weile am Ort hat den Charakter endlicher Ewigkeit. Das Mittel zum Dasein, der Leib, wird erörtert in der Betrachtung von Mittel und Zweck, auch mit Blick auf Kants zweiten kategorischen Imperativ. Die Analysen von Wiederholung und Wiederkehr streifen Einschlägiges von Kierkegaard und Nietzsche und lassen erkennen, wieso erst der Ort ermöglicht, dass es Wiederkehr gibt.
Vom Leib zum Selbst
Authors: Lotz Christian
Published: December 2023

In der vorliegenden Arbeit wird nachgeforscht, welche Form der Subjektivität aus Sicht Husserls und Heideggers für ethische Fragestellungen bereits vorausgesetzt sein muss und wie sich das handelnde Subjekt konkret bestimmen lässt. In einem ersten Teil wird die Umweltanalyse Heideggers aus dem Blickwinkel Husserls kritisch betrachtet. Es wird herausgearbeitet, dass das Umwelthandeln in erster Linie als eine leibliche Sinnstruktur begriffen werden muss, die von Heidegger nicht thematisiert wird. In einem zweiten Teil wird die Selbstanalyse Husserls aus dem Blickwinkel Heideggers kritisch betrachtet. Es wird gezeigt, dass Husserls Handlungsbegriff nicht überzeugen kann. Diese Kritik führt schließlich dazu, das handelnde Selbst als eines zu begreifen, das zunächst vor aller Moralität dazu kommen muss, sich als handelnkönnend zu begreifen. Die Analysen führen schließlich zu einer spezifisch phänomenologischen Interpretation des Verantwortungsbegriffes.
Der menschliche Körper als Gemeinsames Erbe der Menschheit
Authors: Necker Alexander
Published: December 2023

This research study is intended to provide a decidedly political perspective on a topic that is otherwise primarily examined in legal and ethical disciplines: the question of ownership of the human body. It is analysed here using the example of the ownership of human tissue that is used in biomedicine for research purposes as well as in therapeutics and the diagnosis of diseases. The aim of the work is to develop a logically consistent and politically acceptable understanding of human tissue as humankind’s common heritage. For this to be possible—according to one of the work’s central theses—the entire human body must be understood as humankind’s common heritage and not just as human tissue.
Effects of Acupuncture Treatment on Polycystic Ovary Syndrome (PCOS)
Authors: Ramanathan Gunasekaran
Published: December 2023

Polycystic ovarian syndrome (PCOS) is an imbalance of endocrine hormones with a group of symptoms that occur in the reproductive age of females. It is diagnosed by androgen excess and ovarian dysfunction. Many pharmacological-based drugs and treatments are available, however, the effectiveness of existing therapies is less. Yet no cure for PCOS, but symptoms can be managed with medications and lifestyle modifications. Hence, an alternative treatment method is needed for a complete cure. Currently, much clinical evidence has revealed that Acupuncture (AP) and Electro-acupuncture treatment (EAT) are effective treatments for regulating reproductive hormone levels, normalizing testosterone, reducing ovarian cysts, enhancing ovulation, and weakening insulin resistance in normal and obese women with PCOS. Further, β-endorphin has a more crucial role in PCO, AP, or EAT, which may alter the formation of β-endorphin. The mechanism of AP and EAT for PCOS has not been widely reviewed so far. A good understanding of the AP and EAT would be helpful in women with PCOS. This chapter aimed to overview the probable mechanisms and experimental evidence-based data of acupuncture treatment on PCOS in animal models and human patients. We hope that the chapter study will contribute to a better understanding of the PCOS and AP treatment.
Sur quelques destinées posthumes de Dostoïevski
Authors: Pignol Alexis
Published: December 2023

Cet article est un compte-rendu du livre : Catherine Depretto (dir.), Revue des études slaves, XCII 3-4 : « Lectures de Dostoïevski », Paris, Institut d’études slaves, 2021, 272 p., EAN 9782720406645.
Voyages au-delà du visible : le théâtre britannique contemporain à l’heure du « In-Yer-Ear »
Authors: Roussel Nina
Published: December 2023

Cet article est un compte-rendu du livre : Élisabeth Angel-Perez, Le Théâtre de l’oblitération. Essai sur la voix photogénique dans le théâtre britannique contemporain, Paris : Sorbonne Université Presses, coll. « Theatrum Mundi », 2022, 404 p., EAN 9791023107197.
Le dernier livre de Foucault : l’ombre d’un doute ?
Authors: Chevallier Philippe
Published: December 2023

Cet article est un compte-rendu du livre : Michel Foucault, Les Aveux de la chair, Histoire de la sexualité, t. 4, éd. Frédéric Gros, Paris, Gallimard, coll. « Bibliothèques des histoires », 2018, 448 p., EAN 9782072700347.
Le style, au-delà de la littérature
Authors: Maingueneau Dominique
Published: December 2023

Cet article est un compte-rendu du livre : Anna Jaubert, La Stylisation du discours, Paris, Classiques Garnier, collection « Investigations stylistiques », 2023, 290 p., EAN 9782406149385.
Pour une hantologie heureuse : une théorie de fantômes
Authors: Chavoz Ninon
Published: December 2023

Cet article est un compte-rendu du livre : Emmanuelle Sempère, L’Épreuve du fantôme dans la littérature, Paris, Classiques Garnier, coll. « L’Europe des Lumières », 2023, 663 p., EAN 9782406148111
Afrique sur scène : constructions et positionnements identitaires des écrivains afrosporiques
Authors: Ott Marion
Published: December 2023

Cet article est un compte-rendu du livre : Éric Essono Tsimi, De quoi la Littérature africaine est-elle la littérature ? Pour une critique décoloniale, Montréal, Presses de l’Université de Montréal, « Pluralismes », 2022, 307 p., EAN 9782760644649
Des récits qui ravissent
Authors: Jaime Clémence
Published: December 2023

Cet article est un compte-rendu du livre : Anne Duprat, Histoire du captif. Un paradigme littéraire, de l’Antiquité au xviie siècle, Genève, Droz, 2023, 496 p., EAN 9782600064187.
Révolution cherche formule
Authors: Belin Olivier
Published: December 2023

Cet article est un compte-rendu du livre : Zoé Carle, Poétique du slogan révolutionnaire, Paris : Presses Sorbonne Nouvelle, 2019, 330 p., EAN 9782878549805.
Inspection of Welded Joints of Boiler Tubes Using Visual and Penetration NDT Methods
Authors:   JCT service s.r.o., Šafařík Vilém ,   JCT service s.r.o., Bunda Zbyněk ,   JCT service s.r.o., Fink Dominik ,   JCT service s.r.o., Volák Josef
Published: December 2023

The article discusses weld joint defects that were observed during boiler overhaul during shutdown. Visual methods as well as penetration methods were used in the project to check welds. These are mainly the welds of membrane wall pipes and also the welds of pipes for the supply of combustion air. Found weld defects are described and also their photo documentation is included. The aim of this article is to point out recurring defects in welds, especially when replacing membrane wall panels in boilers, and thereby contribute to the prevention of these inhomogeneities.
6183 SAYILI AATUHK m. 110 KAPSAMINDA KAMU ALACAĞININ TAHSİLİNE ENGEL OLMA SUÇU
Authors: SÜMER Seda Yağmur
Published: December 2023

Devlet kamu hizmetlerini kanuni düzenlemeler vasıtasıyla getirdiği birtakım mali yükümlülüklerle karşılar ve sürdürür. Amme alacağı da bu mali yükümlülüklerden doğmaktadır. Amme alacakları, özel alacakların tahsilinden farklı olarak kamu gücüne dayanarak cebren tahsil edilebilmektedir. Amme alacaklarının tahsil usulü Ammeü Alacaklarının Tahsil Usulü Hakkında Kanun’da (AATUHK) düzenlenmişken; özel alacakların ne şekilde tahsil edileceği İcra ve İflas Kanunu’nda (İİK) düzenlenmiştir. Kamu alacağını tahsil sürecinin sağlıklı bir şekilde yürütülebilmesi ve kamu alacağının tehlikeye düşmemesi adına kanun koyucu AATUHK’da birtakım önleyici tedbirler düzenlemiştir. Bu tedbirlere ek olarak bazen ek güvence niteliğinde suç tipi düzenlemelerine de yer verilmiştir. Çalışmamızın konusunu bu maksat ile AATUHK’da yer verilen düzenlemelerden olan “Amme Alacağının Tahsiline Engel Olma Suçu” oluşturmaktadır. Çalışma suç tipini suç genel teorisi ışığında ele alarak suç düzenlemesinde ve uygulamada yaşanan sorunlara değinmeyi hedeflemektedir. Ayrıca yeri geldikçe özel alacakların tahsiline ilişkin kuralları düzenleyen İİK’da yer alan “Alacaklısını Zarara Sokmak Kastıyla Mevcudu Eksiltme Suçu”ile karşılaştırma yapılacaktır. Böylece kamu alacakları ile özel alacakların tahsil mekanizmaları da karşılaştırılmış olacaktır.
Да цъфтят сто цветя, или за криптоморфизма
Authors: Lyutskanov Rosen
Published: December 2023

The paper discusses a possible way of justifying the existence of a multiplicity of cryptomorphic axiomatic theories. It is argued that what renders this multiplicity inevitable are the applications of the theory. They give rise to difficulties whose solution necessitates the application of different conceptual tools. The paper is organized as follows: (§1) introduces the concept of cryptomorphism and the canonic example for the phenomenon: matroid theory; (§2) discusses five cryptomorphic approaches to the definition of rationality in the framework of decision theory: through utility functions, weak orders, choice operators, layered permutations, and pop-stack sortability; (§3) shows that each of these different approaches can serve as a basis for the introduction of a different modification of the original theory. This establishes the heuristic value of cryptomorphic approaches in the domain of decision theory.
(Не)възможност, (не)можене, смърт: Хайдегер и Бланшо
Authors: Enchev Kristiyan
Published: December 2023

This text aims to trace, through Darin Tenev's thesis on the relationship between possibility and negativity, how Heidegger's thinking proposes death as a self-possibility and how not-being-able-to-be in superposition against the horizon of the world ultimately can be interpreted as “sublated” in death as “Dasein's ownmost possibility”. Blanchot, who follows Heidegger in many respects, takes a radically different position towards death, speaking of death as an impossibility, which in the process of dying is less and less owned death.
Условия и условни изречения
Authors: Latinov Evgeni
Published: December 2023

The terms “sufficient condition” and “necessary condition” are related to conditional sentences (those of the form “If A, then B”). The meaning of the former depends on the use of the latter, and conditional sentences are used differently. A conditional sentence could express material implication, but it could also express formal implication. The terms “sufficient condition” and “necessary condition” reflect this difference, each taking on respectively (at least) two different meanings. In the text, I indicate and analyze these meanings. The difference between them is significant because, as it turns out, according to one of them (corresponding to the cases where conditional sentences express material implications), if several conditions together are a sufficient condition for something, then (by logical necessity) only one of them is also a sufficient condition for it, which is not the case with the other meaning (corresponding to the cases in which conditional sentences express formal implications). If the difference in meaning is not taken into account, it is not improbable for situations to arise where mixing them up leads to logical problems. An example of this is given in the text.
Twitter Sentiment Analysis on Circular Economy
Authors: Maulida Syahdatul
Published: December 2023

This research aims to understand the development of public sentiment towards the circular economy. The research adopts a qualitative method with a focus on sentiment analysis using primary data obtained from Twitter. The tweet data is then processed using the VADER Python programming. The results show significant daily fluctuations in the number of tweets discussing the circular economy. The peak tweet activity occurs around the middle of the month, reaching a maximum of 970 tweets. London, England, is noted as the location with the highest tweet activity related to the circular economy, reaching a total of 666 tweets. In terms of sentiment, the majority of tweets exhibit a positive attitude with a percentage of 64.5%. This positive sentiment reflects optimism and support for the concept of the circular economy. The successful implementation of the circular economy paradigm is proven to develop sustainable business and development models, creating hope for a new supportive ecosystem, where economic, environmental, and social sectors are integrated.
Mining Netizen's Opinion on Sustainable Agriculture: Sentiment Analysis of Twitter Data
Authors: Maulida Syahdatul , Devi Abrista
Published: December 2023

This research aims to measure public sentiment related to sustainable agriculture on the Twitter social media platform. The research method involves the extraction and classification of tweet data using a Python Library called VADER (Valence Aware Dictionary and Sentiment Reasoner). The research utilized tweet data posted in the past one year. The results showed fluctuations and decreases in the number of tweets discussing sustainable agriculture. The location with the most tweet activity around sustainable agriculture was Brussels, Belgium, with 642 tweets during the observation period. Word cloud analysis on keywords showed that in positive sentiments, words such as "food security" and "climate change" dominated the visualization. On the other hand, in negative sentiments, words such as "farmer" and "private farmland" appeared more frequently. Overall, the majority of tweets expressed a positive attitude towards sustainable agriculture, with 68.5% positive sentiment. A total of 22.3% of tweets showed neutral sentiments, with no strong positive or negative tendencies. Only 9.1% of tweets contained negative sentiment, indicating that a small proportion of tweets expressed less favorable views towards sustainable agriculture.
Implementation of an Integrated Mobile Livestock Service Program at The Livestock and Animal Health Department of Aceh Province
Authors: Mustaqim Mustaqim , Sari Wenny Novita , Fajri T. Irfan
Published: December 2023

Implementation is the process of carrying out new ideas, programs, or a set of activities with the expectation that others can accept and make changes, conveying several messages, ideas, or concepts through the process carried out by an individual in the sense of human relationships or what is called human relations. Mobile services are one of the implementations that can be applied to livestock information and health management programs. The objective of this research is to determine the implementation of the Integrated Mobile Livestock Service Program at the Livestock and Animal Health Department of Aceh Province. The research approach used in this study is qualitative, which examines the object and reveals existing cases contextually through collected data. Each district surveyed includes 50 people for this mobile cow service program. The observed aspects of this program include: Public complaints about livestock diseases through the application, Interest in using health service information on the application, Public satisfaction with the application. The research results indicate that the complaints found in the community are about scabies and FMD (Foot-and-Mouth Disease). However, these complaints are obtained directly from the community, and only a few come through the application. The average application visitors in Pidie district are 29.87, Bireuen district 29.03, Aceh Utara district 27.47, Aceh Timur district 30.77, and Langsa city 29.33. User satisfaction with the application is assessed through questionnaires given directly to the community. The survey results show that, on average, people still have a limited understanding of the application's usage and are not very satisfied.
„Elaboratul comisiei celor șapte“ din sesiunea Universității săsești din 1862 în contextul discuțiilor privind reașezarea constituțională a Transilvaniei
Authors:   Institutul de Istorie „George Bariţiu” din Cluj-Napoca al Academiei Române, Madly Lorand L.
Published: December 2023

Under the new conditions introduced by the newly enacted Basic Laws (October Diploma and February Patent), the entire Habsburg Monarchy was faced with a redefinition of the position of the crown lands and their internal organization. These had to be carried out under the political tensions that led to the dissolution of the Diet in Pest and the non-convening of the Transylvanian Diet. In 1862, the Saxon National University was the only representative that was functional and also had Romanian members in its ranks. Among the most important documents that were created here was the draft of the Seventh Commission, which intended to implement equality of rights through the creation of national administrative areas. It was also a continuation of the „territorial question" discussions of 1850 and 1851, which has now led to intense disputes mainly with the Hungarian opposition movement, but also to disputes with the Romanian national movement; these were reflected in sometimes extremely critical newspaper articles. The position and the answer of the higher authorities could only be fathomed after intensive consultations. Finally, the transgression of the competences of the Nationsuniversität was determined, since only the provincial Diet could decide in this matter, and this was the way the higher authorities wanted to follow through the future Transylvanian assembly.
Dimitrie Cantemir și Basarabia
Authors:   Institutul de Istorie al Universității de Stat din Moldova, Chişinău, Eșanu Andrei , Eșanu Valentina ,   Institutul de Istorie al Universității de Stat din Moldova, Chişinău
Published: December 2023

In the present study we propose to make a retrospective on the appearance of Bessarabia as a historical-geographical entity, on the approach and perception of this horonym as a distinct space in relation to Wallachia and Moldova in the works of Dimitrie Cantemir. The prince comes with the geographical and cartographic description of this territory, called by the Romanians "Bessarabia", and by the Turks and Tatars "Bugeac", the administrative structure, the ethno-demographic evolution during several centuries, both before and after the annexation to the Ottoman Empire, from which emerges the idea of continuity and resistance of the Romanian population in these lands
Effect of aggregate origin on freeze/thaw resistance of self-compacting concrete with and without a de-icing agent
Authors: Broćeta Gordana , Malešev Mirjana , Radonjanin Vlastimir , Šupić Slobodan , Savić Aleksandar , Lukić Ivan , Cumbo Anđelko , Latinović-Krndija Marina
Published: December 2023

Freezing and thawing cycles, with or without de-icing agents, are the principal causes of concrete structure degradation during the winter. This paper explores the effects of aggregate type on the level of degradation of self-compacting concrete (SCC) due to freeze-thaw (f/t) action. Natural river (NRA) and/or natural crushed (NCA) aggregate, as well as the recycled aggregate of known (RCA-N) and unknown provenance (RCA-A), were employed to produce six different SCC mixtures. The temperature, density, air content, and consistency were determined for fresh concrete, while compressive strength, water absorption by gradual immersion and vacuuming, and frost resistance with and without de-icing salts were tested for hardened concrete. Even though all tested concretes have met the criteria for frost resistance with and without the de-icing salts, it was found that the type of aggregate has a noticeable influence on it. The type of natural aggregate has little effect on SCC frost resistance, but it does influence its behavior when frost and salt are present at the same time. In f/t conditions, RCA-N can be used the same way as natural aggregate, while RCA-A causes the biggest frost resistance reduction. However, both RCAs are not recommended for application in conditions of simultaneous frost and salt impacts.
The improvement of fibrinogen, Ang-1, VEGF, BDNF in post-operative patients with brain trauma through target task-oriented phase training
Authors: Liu Bo , Yu Huan
Published: December 2023

Background: It aims to explore the effect of target task-oriented phase training on fibrinogen (Fbg), angiopoietin (Ang-1), vascular endothelial growth factor (VEGF), serum brain-derived neurotrophic factor (BDNF), and quality of life in post-operative patients with brain trauma. Methods: 142 patients with brain trauma who were operated on in neurosurgery of our hospital from March 2020 to March 2023 were chosen and separated into two groups by random number table. The control group (n=71) received routine post-operative training. The experimental group (n=71) received target task-oriented training based on the control group, and the serum cell levels of nursing for 3, 7, and 14 days were compared. Improvement of limb function and quality of life after 2, 4, and 6 weeks of nursing care is observed. Results: Before nursing, the comparison in serum factor levels, limb function scores, and quality of life scores between the two groups was with P>0.05. After 3, 7, and 14 days of nursing, the Fbg of the control group was higher than that of the experimental group. The Ang-1, VEGF, and BDNF levels in the experimental group were higher than those in the control group (P<0.05). After 2, 4, and 6 weeks of nursing care, the FMA scores of the upper and lower limbs in the control group were lower than those in the experimental group, with P<0.05. The scores in the physiological, environmental, psychological, and social fields of the control group were lower than those of the experimental group, with P<0.05. Conclusion: The application of target task-oriented phase training in patients with brain trauma after surgery can help promote the serum levels of Fbg, Ang-1, VEGF, and BDNF, improve limb function, and enhance quality of life.
The Correlation Of Excessive Assignment Between Student’s Mental Health
Authors: Syahid Abdul , Winna Winna , Kharimah Iffa , Sulliya Lafifah , Suryani Yeni , Komariah Refi , Putri Sulastri Permata Sari
Published: December 2023

This research investigated the correlation of excessive assignments on the mental health of fifth-year English language students at State Islamic Religious Institution in Central Kalimantan. The research hypothesized a strong positive correlation between perceived assignment load and mental health problems. The method of this research used quantitative approach using a questionnaire. The Data was collected from 20 participants. The researchers, analyzed the data using pearson's correlation coefficient JASP to examine the relationship between excessive assignment and mental health condition. Based on the findings, the result showed a significant positive correlation (r = 0.900, p <.001) between excessive assignment and mental health condition, indicating that 81.0% of the variance in students' mental health could be attributed to their perceived workload. Educational institutions should take proactive steps to manage student workloads and provide mental health support services, such as counseling, time management training, and flexible deadlines. Promoting a balanced approach to academic assessment that prioritizes both academic excellence and student well-being is crucial for fostering the success and well-being of English language students. This research limited due to the small sample size and focus on a specific student population. Future research with larger and more diverse samples is needed to further explore the complex relationship between academic demands and student mental health. The findings highlight the urgent need for universities and educators to prioritize student mental health alongside academic achievement. Implementing practical strategies to manage workloads and provide mental health support can promote a more holistic and student-centered educational environment.
EL PATRIMONIO GENÉTICO DE LA HUMANIDAD COMO BIEN JURÍDICO PENAL
Authors: Martínez Pérez María Dolores
Published: December 2023

Este trabajo analiza el contenido del patrimonio genético de la humanidad, tanto su definición cómo su capacidad para ser considerado no solo un bien jurídico sino su relevancia penal y su relación con los delitos relativos a la manipulación genética, así como la técnica de tipificación más adecuada para las actividades que impliquen su puesta en peligro.
Revisiting periurban water (in)security in South Asia
Authors: Narain Vishal , Vij Sumit
Published: December 2023

The Sixth Assessment Report (AR6) of the Intergovernmental Panel on Climate Change (IPCC) has identified periurban development as one of the major drivers of climate risk on vulnerable communities. At the same time, ‘grand challenges’ such as the Covid pandemic and urban–rural contestations create a new imperative for renewed attention to issues of periurban water insecurity by drawing attention to living conditions in periurban spaces where people live in crowded and often informal settlements with inadequate access to safe water. Understanding periurban water insecurity requires paying attention to the dynamic processes of change characterising periurban spaces that make access to water in periurban spaces uncertain and fluctuating. Rather than focus on quantitative indicators of periurban water insecurity or assume that reclassification of jurisdiction status will improve periurban water security, action research with robust partnerships across academia, government and civil society organisations should inform approaches to improve water governance in periurban spaces.
A Role of CREB in BRCA1 Constitutive Promoter Activity and Aromatase Basal Expression
Authors:   Department of Molecular Medicine/Institute of Biotechnology, University of Texas, Health Science Center at San Antonio, USA, Hu Yanfen , Ghosh Sagar , Lu Yunzhe
Published: December 2023

Aromatase is the rate-limiting enzyme in estrogen biosynthesis and a key target in breast cancer treatment. Its ovary-specific promoter, pII, is induced in response to protein kinase A (PKA) activation. It has been proposed that breast cancer susceptibility gene 1, BRCA1, is involved in negative regulation of aromatase pII activity. Surprisingly, inhibition of PKA pathway by inhibitor H89 elevates basal aromatase expression while abolishes cAMP-mediated aromatase induction in an ovarian granulosa cell line, KGN. In this report, we decipher the mechanism by which the PKA pathway negatively regulates aromatase basal expression. We show that PKA pathway plays a positive role in the expression of BRCA1. H89 effectively reduces endogenous BRCA1 mRNA levels as well as reporter gene expression from a BRCA1 promoter. Mutation of a cAMP-responsive element (CRE) in the BRCA1 promoter reduces BRCA1 expression. Chromatin immunoprecipitation (ChIP) shows that CRE-binding protein, CREB, binds to the BRCA1 promoter. Furthermore, knockdown of CREB in KGN cells leads to decreased BRCA1 level as well as elevated basal aromatase mRNA expression. These data demonstrate that both the CRE site in the BRCA1 promoter and CREB are required for BRCA1 constitutive expression. Our study suggests that PKA pathway exerts its negative impact on basal aromatase expression indirectly by contributing to the constitutive expression of BRCA1.
A Validated Adsorptive Stripping Voltammetric Determination of Antidiabetic Agent Pioglitazone HCl in Tablets and Biological Fluids
Authors:   Department of Chemistry, College of Science, Women Student-Medical Studies and Science Sections, King Saud University, Saudi Arabia, Al-Abdulkareem Eman Abdullah , Al-Arfaj Nawal Ahmad , Aly Fatma Ahmad
Published: December 2023

Square-wave adsorptive cathodic stripping voltammetry was used to determine pioglitazone HCl in Britton Robinson buffer of pH5. The adsorptive cathodic peak was observed at -1.5 V vs. Ag/AgCl. The peak response was characterized with respect to pH, supporting electrolyte, frequency, scan increment, pulse-amplitude, accumulation potential and pre-concentration time. Under optimal conditions, the peak current is proportional to the concentration of pioglitazone HCl, and a linear calibration graphs were obtained within the concentration levels of 10-8 and 10-4 M following different accumulation time periods (0-300 s). The obtained results were analyzed and the statistical parameters were calculated. The detection limit is 8.08 × 10-9 M (3.17 ng ml-1) using 300 s pre-concentration time, whereas the quantitative limit is 2.45 × 10-8 M (9.63 ng ml-1). The proposed method was applied to assay the drug in pharmaceutical formulations and biological fluids. The pharmacokinetic parameters of drug in human plasma were estimated as: Cmax=785.8 ng ml-1, tmax=1.5 h, Ke=0.125 h-1 and t1/2 = 8 h which are favorably compared with those reported in literature.
El aula virtual como soporte de la presencialidad. El caso de la materia de algoritmos de programación de la carrera de ingeniería de sistemas de la universidad católica de cuenca en el periodo septiembre 2015 –marzo 2016
Authors: Marín Guamán Marco Antonio
Published: December 2023

Con el surgimiento y la popularización de Internet en la última década del siglo XX, se abrieron nuevas oportunidades en el proceso de enseñanza aprendizaje, puesto que la información se encuentra al alcance de cualquier persona, en cualquier momento y en cualquier lugar, abriendo nuevos horizontes para el sistema educativo en todos sus niveles.
التأثيرات البيئية للطاقة التقليدية الناضبة على التنمية المستدامة (النفط والغاز انموذجا)
Authors: أ.م.د. أخلاص قاسم نافل
Published: December 2023

تُعد الطاقة الناضبة المحرك الرئيس والمكون الأهم لكل النشاطات الاقتصادية ، فلا يزال المستلزم الأمثل في إطار النمو والتطور العالمي ، ولأنها العنصر الأساس لجميع قطاعات الاقتصاد، إذ تعد قضية الطاقة الناضبة واحدة من أهم القضايا ، التي تدخل في معظم مجالات الحياة البشرية على المستوى المحلي والدولي، وأن لها علاقة وثيقة مع انتاج السلع والخدمات ، وذلك باستخدام الطاقة في تكوينها من ناحية ولما لها من صلة هامة بالمصالح الاستراتيجية للأطراف ، التي تتعامل معها ( المنتجة والمستهلكة، من ناحية أخرى. إن معظم الطاقة المستخدمة أو مجملها في العالم هو طاقة تقليدية وغير المستدامة ، وهذا ما تسبب في ظهور مشكلات اقتصادية واجتماعية وسياسية وماسواها، في ظل غياب الإدارة الكفؤة والحقيقية ، وفقدان البعد الاستراتيجي الزمني لأهمية الحفاظ على هذه الطاقة لأمد أطول ، ، فضلاً عن كونها تدخل في تلوث البيئة كنتيجة لانبعاثات ضارة يمكن أن تسببها استخداماتها المتعددة ، مما قد يهدد مسارات واسس التنمية المستدامة التي تعتمد في المقام الأول على حماية البيئة ، وضمان الاستخدام الأمثل والتوزيع العادل للموارد بين الجيل الحالي والأجيال اللاحقة.
BRUXISMO: COMPREENDENDO UM POUCO MAIS SOBRE ESSA PARAFUNÇÃO
Authors: Falcão Bruna Grimaldi Maciel Mota , Almeida Paloma Freitas , Bragatto Giuliano
Published: December 2023

O bruxismo é um hábito parafuncional que envolve os músculos da mastigação e todo o sistema estomatognático, que consiste no hábito de ranger ou apertar os dentes, podendo ser consciente ou inconsciente, durante o sono ou em vigília, sendo, muitas vezes, necessário seu tratamento devido a algumas complicações. Assim, o presente estudo revisou a literatura sobre o tema bruxismo: compreendendo um pouco mais sobre essa parafunção, com o objetivo de evidenciar como o bruxismo pode afetar no estilo de vida do paciente, abordando suas causas, a sua relação com ansiedade, complicações e possíveis tratamentos. Foi utilizado como fonte de pesquisa, informações obtidas nas bases de dados MEDLINE, Scielo e LILACS, nos idiomas português, inglês e espanhol, no período de 1980 a 2023. Essa parafunção é complexa e multifatorial podendo ser através de desordem neurológica ou psiquiátrica e uso crônico de certas drogas. Além disso, podem apresentar causas desconhecidas ou fatores emocionais de estresse e ansiedade. O bruxismo pode causar algumas disfunções como a cefaleia e outros distúrbios em região de cabeça e pescoço como a DTM, além de apresentar sinais clínicos evidentes. Por conta das suas variadas complicações, é necessária uma equipe multidisciplinar para a intervenção dessa parafunção.
TEMPO DE TELA NA INFÂNCIA: UMA QUESTÃO DE SAÚDE PÚBLICA
Authors: Santos Paula , Brito Neves Paulo Ricardo , Leite Nascimento Natália , Balthazar Curi Maria Gabryella , Santos Nascimento Kamila , Martini Giulia , Bragato Fischer Gabriela , Rodrigues Lima Aryanne , Oliveira Santos André Luís , Maia Duarte Ana Carolina , Maria Rosa Vanuza
Published: December 2023

A exposição precoce das crianças às telas aumentou significativamente em todo o mundo, tornando-se motivo de grande preocupação e um problema de saúde pública pelas repercussões negativas que podem acarretar ao neurodesenvolvimento infantil. Objetivo: Conscientizar trabalhadores da área da saúde, pais e educadores sobre os riscos e impactos acarretados pela exposição de tela, de forma inadequada, em crianças de 0 a 10 anos. Metodologia: Trata-se de uma revisão de literatura. Utilizou-se as seguintes bases de dados: Scientific Electronic Library Online (SCIELO), Literatura Internacional em Ciências da Saúde (MEDLINE) e U.S. National Library of Medicine (PubMed-NCBI). “Screen”, “Time” e “Children” foram os termos buscados, com o operador booleano “AND”. Documentos confeccionados pela Sociedade Brasileira de Pediatria e livros de neurologia foram utilizados para o enriquecimento da escrita. Resultados: As informações encontradas demonstram que a exposição precoce às telas pode acarretar disfunções do neurodesenvolvimento e consequências como: obesidade, insônia, dificuldade de aprendizagem, introspecção e dependência digital. Conclusão: Diante do exposto, é uma questão de saúde pública que as consequências da exposição precoce e inadequada de telas sejam divulgadas para pais, cuidadores e profissionais da saúde para que sejam utilizadas a partir da idade e pelo tempo correto.
Analysis of Service Levels on Gojek Customer Satisfaction in the Period After the Covid-19 Pandemic
Authors: Nia Eliza  , Yanti Putri  , Firman Priyanto
Published: December 2023

This research aims to analyze the differences that consumers can feel regarding the differences in the Gojek application before the pandemic, during the pandemic, and after the pandemic. The type of research carried out is quantitative research, usually referred to as using calculated numbers. The population in this study were all 30 Go-Jek application users. In taking samples using the census sampling technique, namely taking samples based on the existing population. The sample in this study amounted to 30 people. The primary data source used in this research is the results of questionnaires filled out by respondents. The data analysis method that will be used in this research is quantitative analysis. In this research, data analysis will use descriptive statistical techniques and multiple linear regression models. The services provided by Gojek do not have a significant influence on the satisfaction of customers using the Gojek application, which means that Gojek has carried out or fulfilled customer desires very well, which has been proven in the results of our questionnaire in the average indicator, which states strongly agree in every question given.
The Influence of Brand Image and Brand Ambassadors on Consumer Purchase Interest in Scarlett Products
Authors: Rani Alika  , Nisa Syafitri  , Ares Permana
Published: December 2023

This research aims to find out whether there is an influence that brand image and brand ambassadors have on consumer purchasing decisions. In this research, researchers used quantitative research methods with causal research. In this research, the target population and sample are women and men who use products from the Scarlett company. The sampling technique used by researchers is purposive random sampling. The sample size was 50 respondents. In this research, the data collection techniques used by researchers were observation and questionnaire techniques. In this research, researchers used the IBM SPSS version 26 program with the aim of analyzing data and calculating statistics on a Windows basis. This research uses multiple regression analyses. The results showed that corporate image, user image, product image, and brand ambassador increased purchasing decisions. With consistent and continuous promotions by brand ambassadors, company can experience a significant increase in sales. Consumers who are interested and confident in the brand will be more likely to buy the company's products. By using brand ambassadors who are well-known and have a wide network, companies can increase the level of public awareness of their brand. Brand ambassadors will promote the brand continuously through social media, events, and shows, thereby creating greater exposure for the brand. People are more interested in and likely to pay more attention to brands promoted by someone they know or admire.
The Influence of Customer Satisfaction, Application Quality and Price Perception on Customer Loyalty in the GRAB Application
Authors: Ega Amalia  , Anggara Dimar  , Susi Oktavia
Published: December 2023

This research aims to determine the influence of customer satisfaction, price quality, and price perception on customer loyalty. Researchers used descriptive methods and a post-positivistic paradigm. The sample used was 73 students who had made transactions on the GRAB application. The data collection technique uses a questionnaire. The data analysis used in this research uses quantitative analysis. In-depth data analysis techniques for quantitative research using regression. Researchers use parametric statistics based on the nature of the data analyzed on an interval scale. Based on the discussion of the research results that have been conducted, it can be concluded that customer satisfaction, application quality, and price perceptions have no influence on customer loyalty. In the data obtained, the majority of respondents were satisfied with the service. The data results show that the service they feel is quite good but still not optimal. If the application can improve service in accordance with customer expectations, a positive perception of the application will arise, and customer loyalty towards the application will increase. According to the results of the data analysis, the majority of respondents felt that the quality of the application was very good. This has a positive effect because it can fulfill customer satisfaction through the application. For price perceptions, the data shows that pricing is good enough but not optimal. For this, you can adjust rates according to customer perceptions.
Peluang dan Tantangan Moderasi Beragama di Era Digital
Authors: Aziz Abdul Rashid Abdul , Rabi'ah Rabi'ah , Ihromi Ihda
Published: December 2023

Keberagaman suku, etnis, bahasa, agama, dan budaya di Indonesia mencerminkan hukum alam yang menuntut penerimaan, tetapi dapat menimbulkan konflik tanpa keseimbangan pemahaman. Sementara menghadapi kompleksitas ini, Indonesia memasuki era digital dengan tantangan seperti penyebaran berita hoax dan pembentukan komunitas radikal di media sosial. Penelitian ini bertujuan untuk menganalisis konsep moderasi beragama sebagai solusi mengelola penyimpangan beragama di era digital. Penelitian ini menggunakan metode penelitian kepustakaan dan peneliti juga mengamati fenomena yang ada di dunia digital tentang bagaimana moderasi beragama. Hasil dari penelitian ini adalah tantangan mencakup penyebaran berita palsu dan komunitas radikal, ditambah polarisasi media sosial yang bisa menjadi wadah bagi ideologi ekstrem. Di sisi lain, peluang moderasi beragama muncul dari ketersediaan sumber informasi yang melimpah, seperti narasi dan video dakwah moderat, yang bisa efektif dikelola untuk menanamkan nilai-nilai moderasi. Pendekatan lainnya mencakup pembuatan konten digital untuk menyebarkan pemahaman moderasi yang menarik perhatian pengguna internet.
EFISIENSI GABUNGAN MODEL PBL, GI DAN TALKING STICK UNTUK MENINGKATKAN AKTIVITAS DAN HASIL BELAJAR SISWA KELAS 5
Authors: Febriatina Anisa , Anwar Khairil
Published: December 2023

Sehubungan hasil temu duga bersama wali kelas 5 SDN Alalak Selatan 2 Banjarmasin, persoalan pada penelitian ini adalah rendahya pemehaman peserta didik terhadap pembelajaran Bahasa Indonesia materi teks bacaan dan rendahnya aktivitas peserta didik, hal ini disebabkan oleh pendidik yang hanya memberikan penyampaian materi menggunakan metode ceramah, tidak menggunakan model dan media sehingga peserta didik merasa jenuh dengan pembelajaran. Tujuan dari penelitian ini ialah guna mendeskripsikan aktivitas pendidik, aktivitas peserta didik dan hasil belajar. Metode yang digunakan dalam penelitian ini ialah kualitatif dan kuantitatif. Hasil penelitian ini menunjukkan bahwa terjadi peningkatan aktivitas peserta didik yakni siklus 1 (pertemuan 1) memperoleh persentase klasikal 7%, siklus 1 (pertemuan 2) memperoleh 34%, siklus 2 (pertemuan 1) memperoleh 83% dan siklus 2 (pertemuan 2) memperoleh 97%, sehingga hal ini memberikan dampak yang positif pada hasil belajar, karena dengan meningkatnya aktivitas peserta didik maka hasil belajar juga akan meningkat. Berdasarkan temuan dalam penelitian ini bahwa gabungan model Problem Based Learning (PBL), Group Investigation (GI) dan Talking Stick dapat meningkatkan aktivitas dan hasil belajar peserta didik.
PENGARUH PERFEKSIONISME, MANAJEMEN WAKTU, DAN INTERNAL LOCUS OF CONTROL TERHADAP PROKRASTINASI AKADEMIK MAHASISWA
Authors: Dara Yohana Lastri , Wolor Christian Wiradendi , Marsofiati Marsofiati
Published: December 2023

Tujuan dari penelitian ini adalah untuk mengetahui pengaruh Perfeksionisme, Manajemen Waktu, dan Internal Locus of Control terhadap Prokrastinasi Akademik. Penelitian ini menggunakan metode kuantitatif dengan instrumen kuesioner. Terdapat 3 hipotesis dengan jumlah sampel sebanyak 100 responden yang merupakan mahasiswa aktif Pendidikan Administrasi Perkantoran UNJ. Kemudian jawaban responden yang telah diperoleh dianalisis dengan Structural Equation Modelling – Partial Least Squares  menggunakan software SmartPLS 4.0. Temuan dari penelitian ini menunjukkan bahwa 1) Perfeksionisme memiliki pengaruh yang tidak signifikan dan negatif terhadap Prokrastinasi Akademik. 2) Manajemen Waktu memiliki pengaruh yang signifikan dan negatif terhadap Prokrastinasi Akademik. 3) Locus of Control Internal memiliki pengaruh yang tidak signifikan dan negatif terhadap Prokrastinasi Akademik.
Formation of labor resources in rural areas methodological issues
Authors: Rəhimli Hüseyn
Published: December 2023

The formation of working-age population groups in terms of modern labor market requirements in the conditions of the market economy lays the groundwork for an easy solution to their employment problems. These problems cover the rural economy. There fore, the article explores the options of using justified methodological approaches and reliable forecast data in the formation of labor resources.

Purpose–to systematically and comprehensively study the characteristics of the formation of labor resources in order to solve the employment problem in rural areas

Methodology-the study used the method of comparative analysis and synthesis.

Research results-the use of opportunities of economic-mathematical modeling is of great importance in solving the methodological problems of the formation of labor resources in rural areas.