bluuebunny/crossref_metadata_2025 huggingface dataset:
Socio-economic development of tourist destinations: A cross-country analysis
Authors: Stryzhak Olena , Cibák L'uboš , Sidak Mykola , Yermachenko Volodymyr
Published: February 2024

The study aims to investigate the characteristics of socio-economic development in the context of countries’ tourism advancement. The paper analyzes the Travel & Tourism Development Index (TTDI) and the Happiness Rating (HR). The sample covers data from 102 countries for the year 2021. The analysis showed that there are differences in the relationships between TTDI and HR, as well as their sub-indices, among groups of countries distributed according to income level. The research methodology includes the use of such methods as correlation analysis to determine the relationships between indicators like factor analysis to identify the degree of indicators' influence on the sample and a graphical method to visualise the analysis results. The study uses the World Bank approach to classify countries into income groups. The study confirms that a country's welfare level is one factor that determines patterns in various areas, including tourism.
PHILOSOPHY OF GENDER: ECONOMIC BACKGROUND GENDER RELATIONS
Authors:   Kyrgyz State University named after I. Arabayev, Nusupova Saikal , Nusupov Cholponbai ,   Kyrgyz National University named after J. Balasagyn
Published: February 2024

This paper examines the problems of gender relations, viewed through the prism of economic factors that determine the social status and role of women in various areas of labor organization. Moreover, a philosophical and economic analysis of the correlation of gender and gender differences in society is given, the position on the fallacy found in the scientific literature, the definition of professions classified as “female”, is substantiated while replacing gender aspects with proper sexual ones, associated with the moral characteristics of the female sex. The objective dependence of gender principles on economic causes and political processes, determined by such factors as what form of ownership and what socio- political system exists in a particular historical society, is revealed. Thus, in particular, it highlights how the institution of private property has a direct impact on the content and direction of gender relations, viewed through the prism of social activity and the orientation of their subjects.
SOCIO-PSYCHOLOGICAL ISSUES IN GENDER RELATIONS
Authors:   ", Salmorbekova Rita ,   Ala-Too",   International University, Zhakshylykova Tinatin ,   "Ala-Too" International University
Published: February 2024

The problem of gender equality is one of the most urgent problems today. The article provides an in-depth analysis of the socio-psychological situation in gender relations. In any society, in the psychological consciousness, men and women have a role to play. It is very difficult to follow the rules and to clearly observe gender roles. The socio-psychological, especially the economic situation has a significant impact on the observance of gender interests in society. An in-depth analysis of the most realistic changes in socio-cultural conditions and changes in gender relations. The gender crisis is currently affecting men in Kyrgyz society, and ways needbe developedeloped to get them out of depression. It is proved that this situation depends on the social, psyc Psycholcal, and economic conditions of society as a whole.
POLITICAL CULTURE OF WOMEN IN KYRGYZSTAN
Authors:   The Academy of public administration under the president of Kyrgyz Republic named after Zh. Abdrahmanov, Torogeldieva Baktykan
Published: February 2024

The article analyzes the changes in the political culture of women during the period of democratization of Kyrgyzstan. Women's political subculture is studied as a new political actor in state decision-making. The unique experience of involving women of the Republic in the public life of the state through participation in the activities of the Parliament (Jogorku Kenesh) and the civil sector of the Republic, i.e. involvement of women in the activities of political, public associations, and organizations. The effectiveness and organization of the work of women deputies is shown, despite their small number and the importance of women's participation in politics and in state-level decision-making. The political culture of women is shown as one of the most important conditions for the socio-political stability of society.
THE PHENOMENON OF "OBON" IN THE KYRGYZ SOCIETY
Authors:   International Public Foundation “Roza Otunbayeva Initiative”, Shaidullaeva Topchugul
Published: February 2024

The intensification of political events in Kyrgyzstan brought many changes in the behavior of women., The emergence of the OBON groups (detachment of women for special purposes) attracted attention turning into a subject for the games of certain political forces in the last 10 years. The results of our sociological research showed that the development of the OBON Institute in Kyrgyzstan is not a coincidence. It was born in our society where high-level corruption, lawlessness, and scandals are flourishing. The article analyzes the following questions: What is "OBON"? What is their origin? What factors lead them to their emergence? Why are their activities not banned, etc.?
GENDER EQUALITY IN EDUCATION
Authors:   KNU named after J. Balasagyn, Akmatalieva Nasipa
Published: February 2024

This article focuses on how and why education is the key to gender equality, as well as the importance of gender equality in the education system to create better conditions for girls under traditional pressure. It will also raise the question of whether there is a need for an educational philosophy that provides the same opportunities for young women and men, teaching the same things at the same time, in the same place, using the same methods, and within the same system. Numerous studies show that society often treats boys and girls differently. Although gender inequality in education has changed dramatically in recent decades thanks to the struggle for women's rights, gender inequality continues to flourish today.
DESIGN AND DEVELOPMENT OF COST-EFFECTIVE MEANS TO SUPPORT COMMUNITIES IN COVID-19
Authors:   Sam Houston State University, Dakeev Ulan
Published: February 2024

Since the World Health Organisation (WHO) has declared the novel coronavirus (COVID-19) outbreak a global pandemic in March 2020, the crude mortality rate, as well as the morbidity associated with COVID-19, has rapidly increased worldwide. As this novel coronavirus could spread easily through person-to-person close contact, primarily in respiratory droplets from infected individuals, or contact with contaminated surfaces, the global outbreaks had grown at an exponential rate. To reduce the contact with the contaminated surfaces, a disinfection booth has been constructed to minimise the individual contaminated rate on surfaces such as clothes and shoes.
SOCIAL MEDIA USAGE ASPECTS OF UNIVERSITY STUDENTS: ON THE EXAMPLE OF KYRGYZ STUDENTS
Authors:   The London School of Languages and Cultures, Kadenova Zhanara , Kaparov Nurdin ,   "Ala-Too" International University
Published: February 2024

In today's society where internet technology is developing, social network platforms have become an integral part of personal life. People use social media for a variety of purposes such as chatting, tracking news, having fun, and joining social groups. The research was carried out on university students studying in Bishkek, Kyrgyz Republic. In this study, five aspects of social media usage are discussed: (i) which equipment students use most in accessing social media platforms, (ii) how many years they have been using, (iii) how many hours they spare per day to surf in social media platforms, (iv) which social media platforms students use most, and (v) for which purposes they use. Afterwards, findings were analyzed and suggestions were given.
SUBJECTIVITY OF FEMALE NATURE IN CH. AITMATOV’S NOVEL “JAMIYLA”
Authors:   International University of Kyrgyzstan, Каraeva Zina , Edilova Mariam ,   International Ala-Too University
Published: February 2024

In this article the story of the writer and philosopher Ch. Aitmatov’s “Jamiyla” is researched in the context of the philosophy of gender (philosophy of women and men). Many peoples of the world including the Kyrgyz patriarchal culture gave priority to men and women are considered as passive objects. The figure of Jamiyla by Ch. Aitmatov showed the beautiful nature of Kyrgyz women as a self-confident human being who is entitled to all rights. Identifying the women as not a passive object but active human being. Ch. Aitmatov proves the existence of radical feminism and gender theory in the real life.
ON THE HARMONIC BALANCE METHOD FOR CONSTRUCTING A PERIODIC SOLUTION TO A SYSTEM OF AUTONOMOUS INTEGRODIFFERENTIAL EQUATIONS WITH INFINITE AFTEREFFECT
Authors:   Kyrgyz State University named after I. Arabayev, Alimbaev Asangul , Bapa kyzy Ainura ,   Issyk-Kul State University named after K. Tynystanov
Published: February 2024

The harmonic balance method refers to the type of Galerkin method and is an analytical method that makes it possible to find an approximate solution to a periodic boundary value problem in the form of an analytical expression. This property of the Galerkin method emphasizes its universality for the study of periodic solutions of both differential and integral- differential equations. This article considers the problem of constructing a periodic solution to a system of integral-differential equations with infinite aftereffects. This type of system describes a mathematical model of the interaction of two types of populations with the property of memory in past times.
THE IMPORTANCE AND CONDITIONS OF STUDYING GEOMETRIC MATERIAL IN THE ELEMENTARY SCHOOL
Authors:   Kyrgyz State University named after I. Arabayev, Kasymalieva Gulmira , Seytalieva Elmira ,   Kyrgyz State University named after I. Arabayev, Saliyeva Gulzhan ,   Kyrgyz National University named after J. Balasagyn
Published: February 2024

The article contains theoretical questions and information on geometric material in elementary school. The importance of the development of students in the process of teaching geometric thinking which is a type of visual-figurative and geometric thinking is highlighted. The study of geometric material for a primary school student is carried out by his logical thinking and provided by various mental processes. Analyzes of systems for studying geometric concepts and relationships both in traditional and alternative systems of teaching mathematics in primary school have been carried out. This article provides structural analyzes of the system for studying geometric material of the two most popular systems for teaching mathematics to primary school students. Analyzes of primary school mathematics textbooks by authors I.B. Bekboev and N.I. Ibraeva, L.G. Peterson are considered.
STUDY OF EATING DISORDERS AND EATING BEHAVIOR IN STUDENTS
Authors:   Asian Medical Institute named after S. Tentishev, Saryeva Aigerim , Abakirova Aigul ,   Asian Medical Institute named after S. Tentishev
Published: February 2024

The study of eating disorders and the possible causes of their occurrence is an important direction in modem research. The purpose of the study was to study eatingdisorders and eating behavior in students of students' age. The «Eating Behavior rating Scale» D.M.Gamer adapted by O.A.Ilchik. The sample consisted of 84 students aged 20 to 28. The author considers the concept of eatingdisorders andeatingbehavior, types of disorders, various the ories of their occurrence, саuses, symptoms, diagnosis, treatmentand psychotherapy.
PRINCIPLES OF COMPILING A MULTILINGUAL AUTOMATED DICTIONARY OF DIPLOMATIC TERMINOLOGY
Authors:   Diplomatic Academy of the Ministry of Foreign Affairs of the Kyrgyz Republic named after Kazy Dikambaeva, Bektenova Raushan
Published: February 2024

In the context of the accelerated development of world relations and the growing importance of diplomacy, it becomes critically important to ensure clear and accurate communication between States and international organizations. Multilingual automated dictionaries of diplomatic terminology are an effective tool to help in achieving this goal. Diplomatic activity plays a fundamental role in the modern world. It ensures international relations, cooperation and conflict resolution between States. The central element of diplomacy is the using of specific terminology, which has many nuances and variations in different languages. In this context, the creation of a multilingual automated dictionary of diplomatic terminology becomes an important means of facilitating international communication and understanding. This article discusses the basic principles of compiling such dictionaries, including the stages of collecting and analyzing of terminology, methods of automated data processing, maintaining relevance, as well as aspects of multilingualism and cultural adaptation.
VERBS EXPRESSING A PSYCHOLOGICAL STATE IN THE KYRGYZ LANGUAGE
Authors:   Kyrgyz State University named after I.Arabaev, Zholdoshalieva Nargiza , Ajymambetova Dilbara ,   Kyrgyz State University named after I.Arabaev
Published: February 2024

The article examines the verbs of the psychological state of a person in the modern Kyrgyz language and the semantic nature of the verb group expressing the mental state in it. The psychological state of a person as an integral mental process is a physiological reaction and an external expression of internal subjective content through verbal predicates, which is the essence of our scientific work. A person as a subject of mental activity not only causes certain changes in life, but also affects other people, and also feels and perceives what is happening in the environment. Positive and negative emotions, pleasant and unpleasant feelings in a person's character are expressed through a language function, in our work we use semantic predicates, which are analyzed in this article.
NUMERICAL ANTONYMS (based on the works of Ashym Dzhakypbekov)
Authors:   National Academy of Sciences of the Kyrgyz Republic, Iimangazieva Aida
Published: February 2024

Numbers occupy a special place in human life. It is impossible toimagine our life without numbers. Our daily life, all branches of science areclosely connected with these words. The above group of words numerals inlinguistics refers to parts of speech. This is a group of words well studied in thescience of the world and Kyrgyz languages and focused on one direction in thelanguage system. On the basis of scientific works related to this topic, the famous writer A. Dzhakypbekov, we can analyze the numerical antonyms in his works. We perceive and cognize the world around us, natural phenomena with our senseorgans. For example, our 24 hourday depends on the number of day. In this article, we aretalking about the formation of numerical antonyms, in the ratio of wordscontaining numerical values and the origin of words expressing number in stablephrases. In general, I would like to reveal the nature and originality of the opposite, which includes numerical values in the works of art byА. Dzhakypbekov.
MUTUAL DIVISIONS OF LITERARY TRANSLATION AND THEIR FEATURES
Authors:   Osh State University, Ismailova Rizvan
Published: February 2024

The article states that grammatical forms, syntactic constructions, sentence symmetry, syntactic figures, rhythmicity of poetic and prose speech, repetitions, parallelisms, etc. in the text have their own national and cultural specifics. Due to the absence or underdevelopment of fundamental works on translation studies, translation criticism, translation history and translation theory in the native language in the native language, we are not able to select and present to the general reader the best translations that clarify the qualitative characteristics, specific features and mutual differences of a true literary translation. Literary translation requires the highest level of equivalence, which can only be achieved by a creative, diligent, experienced translator, overflowing with translation skills. Indeed, in the history of literature there are poets and writers who became famous for their free translation. One of the main tasks of the translator is to provide the full content of the original, where the content of the original and the translation is identical, compatible and the correct translation is very important. Equivalence is the component that fulfills and implements this unity.
REFLECTION AND THE MODERN ROLE OF THE CUSTOMS OF THE KYRGYZ PEOPLE IN LITERARY WORKS
Authors:   Kyrgyz National University named after Jusup Balasagyn, Kudaibergenova Zeinep
Published: February 2024

The article discusses the issues of representation of Kyrgyz customs in literary works and their modern significance. The customs of the people have existed for a long time since the birth of each nation, were formed due to a certain ethnic environment and historical conditions, have relative stability only within each nation, group and nation living there and are constantly moving from one society to another. the other, with the help of the force of public opinion, is realized and supported. The customs have undergone some changes over time, and most of them still perform their function and live among the people. In particular, we are witnesses to the fact that the traditions of lullabies, weddings, blessings and consecrations are not in the form in which they are currently reflected in folk art and literary works, but have undergone significant changes. Customs have undergone some changes over time, moreover, customs and traditions are widely represented in Kyrgyz literature, and the article proves that they represent a social rule that has been continuously passed down from generation to generation as a heritage and has been preserved for a long time. The content of the article ended with the remark that in modern times, excessive use of traditions does not benefit our people.
PHONOSTATISTICAL ANALYSIS OF LAMENTATIONS OF THE VAN KYRGYZ
Authors:   Bishkek State University named after K.Karasaev, Tashpolot Sadykov , Sharshembaev Bakyt ,   Kyrgyz-Turkish Manas University, Sherova Atirgul ,   Batken State University
Published: February 2024

The article provides a phonostatistical analysis of the language of the Kyrgyz tribes who emigrated from the Small Pamir to Turkey and settled on the territory of Van, based on the work of S. Kaipov "Lamentations of the Pamir Kyrgyz living in Turkey". As Linguistic Folklore Source: Research and Text". – Bishkek: Central Asian University, 2015. The studied texts of lamentations contained in the book are devoid of folklore information about from whom, when and where they were written, the text is cleared of additional linguistic signs, the iotized letters were separated, as well as the sounds қ, ғ, к, г are clearly separated by separate letters, the flat slit soft consonant β, pronounced as labial-labial (not labial-dental b), transcribed as a standard letter w, long vowels marked with a colon are represented by double letters in the form of аа, әә, ээ, оо, өө, уу, үү the studied corpus was loaded into a computer with a pure sequence of sounds, processed and analyzed, phonostatistical data confirming the presence of sounds at the beginning, middle and end of the word were obtained. The article considers the classification of sounds used in the texts of lamentations, the general phonostatistics of sounds, as well as the phonostatistics of vowels at the level of their distinctive features, in this regard, the phonostatistics of the texts of lamentations is compared with the text of the epic "Manas" according to the variant of Zhusup Mamai, their common and distinctive features are revealed.
QUESTIONS OF PARTICIPATION OF ELEMENTS OF INTUITION, ARCHETYPE AND COLLECTIVE CONSCIOUSNESS IN FICTION
Authors:   Jalal-Abad State University named after B.Osmonov, Chokoeva Dilbar
Published: February 2024

Subject of the article: scientific analysis of the content of the "magic realism" method in Russian literature. Purpose: to conduct a scientific analysis of the thoughts and actions of the heroes of realistic works of national literature: how the elements of intuition, the national archetype and collective consciousness are involved, and in what "methods" magical realism is created. Research method: comparative literature. In the article: The origins of the "magic realism" of the Kyrgyz national literature: attempts to prove it in the mythological and folklore works of the Kyrgyz, in their traditions and ideas formed from a divine point of view, in their moral and ethical principles, in the collective national consciousness (subconscious), archetype and in the personal intuition of the characters. As a result, there will be an attempt to scientifically prove that intuition, archetype and origin of collective consciousness: "quantum field", ancient. The practical significance of the article: the rationale for the transformation of Russian fiction from the aspect of magical realism and the laws of the "quantum field" into the actual aspect of the study. The relevance of continuing this topic in the future: there is no doubt that a scientific analysis of the origins of magical realism in our national literature from the above aspects will give very interesting results. consciousness with discrete ideas about the possibilities of quantum physics.
LEXIKO-SEMANTIK FEATURES OF WORDS RELATED TO THE KOMUZ AND ITS PARTS
Authors:   Kyrgyz State University of Culture and Arts named after B.Beishenalieva, Chekeeva Begaim
Published: February 2024

The article notes the place of komuz in the life of Kyrgyz people and its role in national music. The factors of the lexeme komuz are considered. A linguistic analysis of the name of musical instrument chertme komuz and its parts waz carried out. The names of the types of national musical instruments and semantic features were also analyzed. The association of the names with imitatiwe words and the human anatomy is indicated. It is noted that the stringed komuz is one of the oldest musical instruments and under different names it has spread among other nations. It has been interpreted that komuz means not onlu a musical instrument, but also expresses the modernThe names of improved types of musical instr semantics of komuz genre komuz language, the word used to expel demons from oblivion, as well as contains an emprty decimal sound. The name ofimprowed types of musical instrument komuz are determined. The emergence of nouns "chertmek", "kol komuz" along with the word on the basis of synonymy is considered.
THE PROBLEM OF ETHNIC IDENTITY AND TRADITIONAL CULTURE
Authors:   Bishkek State University named after K.Karasaev, Botokanova Gulnara , Tologonova Meerim ,   Bishkek State University named after K.Karasaev
Published: February 2024

The article deals with the definition and essence of ethnic identity. The authors consider a variety of approaches and concepts on this issue and note that the existing concepts to determine the nature, essence of the ethnos make it possible to form new concepts that integrate the most significant aspects of the study of the ethnos. Ethnic identity can be viewed as an integral system, including such components as linguistic, cultural, state, territorial, symbolic communities. At the same time, it should be noted that these components are not unique phenomena when a person is identified with a particular ethnic community, since these components are mobile and dynamic in nature. The authors come to the conclusion that traditional culture, along with language, is a kind of symbol in which every nation sees the guarantee of preserving its ethnic identity, capable of accumulating and transmitting people's social experience, acts as a kind of ethnic memory of the people, which is the basis of ethnic identity.
PRESERVATION AND DEVELOPMENT OF THE KYRGYZ SONG PERFORMANCE TRADITION IN MODERN CONDITIONS
Authors:   Kyrgyz State University of Culture and Arts named after B.Beishenalieva, Koldoshov Tumonbai
Published: February 2024

The functioning of Kyrgyz folk song folklore in modern conditions is considered as a factor in the preservation of musical culture. The article discusses the problems of the existence and preservation of song performing tradition of the Kyrgyz people. The place and role of the Kyrgyz folk song in musical culture is noted, as a work of oral and professional creativity, which is undoubtedly distinguished by its exceptional richness and wide variety. The purpose of the article is to preserve the song performing traditions that occur in folk song culture at the present time, to determine their causes and predict their results and identify characteristic trends. The article also identifies positive and negative aspects associated with preservation processes in folk musical culture. The historical perspective of folk song performing traditions is revealed. A set of measures is proposed to preserve and develop the traditions of folk song performing art. The idea is that the Kyrgyz song is an important component of the musical, cultural and historical heritage of the Kyrgyz people.
AL-FARABI AND FINANCIAL POLICY OF KYRGYZSTAN: THEORY AND PRACTICE
Authors:   Ala-Too International University, Nazarkulova Nurzhan
Published: February 2024

Al-Farabi (also known as Abu Nasr Muhammad ibn Muhammad al-Farabi) was a famous Arab philosopher and scholar who lived in the 9th century. His work covered many different areas, including philosophy, politics, ethics, music, astronomy, and logic. Although his work was not directly related to economics, his philosophical and political ideas influenced the development of political and economic thought in the Arab world and later in history. This article is about Al-Farabi and his economic theory. Financial policy is an important component of the economic policy of Kyrgyzstan. It covers various measures and tools that the state uses to manage the financial sector and stimulate economic growth. In this article, we will consider the main aspects of the financial policy of Kyrgyzstan and the theory of Al Farabi.
CHINGIZ AYTMATOV AND MUSIC
Authors:   National Academy of Sciences of the Kyrgyz Republic, Tokoeva Jumabubu
Published: February 2024

“Chingiz Aitmatov and Music,” the author analyzes the issues of the relationship between Ch. Aitmatov’s creativity and music. Moreover, these relationships are considered at two levels: music, its role in the works of Ch. Aitmatov and the musical interpretation of the works of the great writer. The author shows the role of music in revealing the characters of Aitmatov’s heroes, in deepening the content of works, as an element of poetry and as a tool for philosophical reflection. When considering the musical interpretation of Aitmatov’s works, the author dwells on identifying, according to the comparative typological method, the similarities and differences between opera productions, as well as the musical accompaniments of the writer’s screen works, showing the strengths and weaknesses of opera productions and screen adaptations in the context of intercultural relationships, as well as the peculiarities of the actors’ performances, their originality and skill, some shortcomings and omissions in the musical interpretation of images.
LANGUAGE AND CULTURE AS AN IMPORTANT FACTOR ETHNIC POLICY
Authors:   ", Erkinbekov Kylychbek ,   Bishkek Innovation College",   institution
Published: February 2024

As noted in the scientific article of the authors, language occupies a central place in all communicative activity. It is equally regarded as a means of organizing and structuring the external world, providing experience, and serves as the main "satellite" of information between participants in the communication process. The characteristic constructions of the language include elements of the way of thinking that are characteristic of its speakers. The very way of thinking is determined to a certain extent by constructive, lexical, semantic and phonetic differences and the possibilities of the language, as well as by individual and ethnic experience. In addition, language is considered a natural barrier for the entry of “strangers” into the semantic field, where the intellectual and spiritual existence of the people is realized. This linguistic reality of social interaction often serves as covert discrimination against strangers with limited language skills of the host society.
ANALYSIS OF EMPLOYMENT IN THE EDUCATION SYSTEM OF THE KYRGYZ REPUBLIC IN 2003-2022
Authors:   Ministry of Education and Science of Kyrgyz Republic, Supanaliev Bekjan
Published: February 2024

At the Sustainable Development Goals (SDGs) Summit of the 78th session of the UN General Assembly in September 2023 President of the Kyrgyz Republic S.N. Zhaparov declared Kyrgyzstan’s readiness to undertake concrete commitments to accelerate the achievement of SDGs by 2030 and its desire to become one of the top 30 countries by 2030. According to the UN Report on Sustainable Development in 2023, the Kyrgyz Republic took 45th place out of 166 countries studied. At the summit, the "Education" SDG-4 was identified as Kyrgyzstan’s main commitment to achieve the SDG by 2030, which in turn should have a multiplier effect on the achievement of other SDGs. The article studies the dynamics of the indicators of the employed population in the main work by types of economic activity and territory in the education sector, covering all seven regions of the republic and the city of Bishkek from 2003 to 2022
Müzik Öğretmenlerinin ve Müzik Eğitimi Uzmanlarının Teknolojik Pedagojik Alan Bilgisi (TPAB) Yeterlikleri Hakkındaki Görüşleri
Authors: KOCAKAPLAN Yusuf , AKKAŞ Salih
Published: February 2024

Bu çalışmanın amacı, müzik öğretmenlerinin ve müzik eğitimi uzmanlarının teknolojik pedagojik alan bilgisi yeterlikleri hakkındaki görüşlerini belirlemektir. Teknolojinin eğitim öğretim sürecine entegre edilmesine bu denli vurgu yapılırken müzik öğretmenlerinin ve müzik eğitimi uzmanlarının TPAB yeterlikleri hakkındaki görüşlerinin öğrenilmesinin ve değerlendirilmesinin gerekliği görülmüştür. Çalışmaya 2022-2023 eğitim öğretim yılında Ankara’daki özel ve devlet okullarında görev yapmakta olan toplam 35 müzik öğretmeni ve Türkiye’deki çeşitli eğitim fakültelerinde öğretmen yetiştiren 32 müzik eğitimi uzmanı katılmıştır. Araştırmada nitel araştırma yöntemlerinden durum çalışması deseni kullanılmıştır. Açık uçlu anket soruları ile toplanan veriler betimsel analiz yöntemi ile analiz edilmiştir. Yapılan analiz sonucunda TPAB kategorilerine göre analiz edilen görüşler madde olarak yazıldığında, müzik öğretmenlerinin görüşlerinden toplam 22 yeterlik maddesi, müzik eğitimi uzmanlarının görüşlerinden ise toplam 55 yeterlik maddesi yazılmıştır. Verilerden analiz edilen maddeler incelendiğinde, en fazla yeterlik maddelerinin alan bilgisi ve pedagoji bilgisi kategorisinde belirtildiği görülmüştür. Teknolojik pedagojik bilgi ve teknolojik pedagojik alan bilgisi alanlarında ise diğer bilgi türlerine oranla daha az yeterlik maddesi belirtilmiştir.
COVİD-19 Pandemisi Sürecinde Özel Eğitim İhtiyacı Olan Çocuklara Verilen Uzaktan Eğitimin Ebeveynler Tarafından Değerlendirilmesi
Authors: KÖKEN Hatice İlay , SAZAK DUMAN Elif
Published: February 2024

Bu araştırmanın amacı COVID-19 pandemisi sürecinde özel eğitim ihtiyacı olan çocuklara verilen uzaktan eğitimin ebeveynler tarafından değerlendirilmesidir. Araştırmanın kapsamında 7-12 yaş arasında olan özel eğitim ihtiyacı olan çocuğa sahip olan 350 ebeveyne ulaşılmıştır. Araştırma için kullanılan veri toplama aracı araştırmacılar tarafından geliştirilen COVID-19 Pandemisi Sürecinde Uzaktan Eğitimle Sürdürülen Özel Eğitime İlişkin Ebeveyn Görüşleri (COVID-19 UESÖEG) isimli anket formudur. Veriler betimsel istatistik yöntemleri kullanılarak analiz edilmiştir. Araştırmada uzaktan özel eğitim hizmetlerinin düzenli olmasına rağmen çocukların öğrenme düzeylerinin farklı olması, ekonomik yük getirileri ve bakım için ayrılan süredeki artıştan dolayı uzaktan eğitimin verimli olmadığı sonucuna ulaşılmıştır. Uzaktan özel eğitimle ilgili olarak ebeveynlerin yaşadıkları zorluklar; ödevleri tamamlamada ebeveynin konuyla ilgili bilgi eksikliği, uygun olmayan ev ortamı ve yetersiz zaman başlığı altında toplanmıştır. Araştırma kapsamında özel eğitim ihtiyacı olan çocuğa sahip ebeveynlerin COVID-19 pandemisi sürecinde aldıkları uzaktan eğitimden daha fazla yararlanmak için sunduğu öneriler ise daha uygun desteklerin verilmesi gerektiği, okul-ev ilişkisinin daha fazla olması gerektiği ve çalışmalar için daha esnek saatlerin ayarlanması gerektiği şeklindedir.
Synthesis of in vitro transcribed RNA from whole bacterial transcriptome v1
Authors: Reddy Morampalli Bhargava , Silander Olin
Published: February 2024

Identifying RNA modifications across the transcriptome has been made possible by direct RNA sequencing using nanopore sequencing from Oxford Nanopore Technologies. This is due to voltage changes happening when each nucleotide passes through the pore. Hypothesis is that since each nucleotide passing through the pore has a distinct change in voltage, nucleotides with epigenetic modifications (e.g.methylation) also has distinct voltage changes when passing through. This is identified by errors in basecalling. Several software have been developed to identify locations of modifications using machine learning, deep learning models. In order to make highly accurate predictions, there is the necessity of comparing the signals from native RNA sequencing with RNA without any modifications. A few recent research publications get RNA through in vitro transcription but only for ribosomal RNAs (rRNA). This is easier since there are only 7 different ribosomal RNAs for each type i.e., 16S, 23S and 5S. Getting IVT RNA for entire transcriptome is not trivial since bacterial transcriptome is complex and depends on the condition the bacteria has been grown in. We use the method of strand switching during cDNA synthesis to get cDNA for whole bacterial transcriptome which can then be used as a template for IVT.
Ultrassonografia na prática assistencial do enfermeiro do bloco operatório: revisão de escopo
Authors: Gomes Eduardo Tavares , Santos Rafaela Ingridy dos , Adelino Simone Danielly Vidal de Negreiros , Oliveira Jacqueline Augusta do Nascimento , Popov Débora Cristina Silva
Published: February 2024

Objetivo: Identificar na literatura científica aplicações para o uso da ultrassonografia por enfermeiros no bloco operatório. Métodos: Revisão de escopo realizada de acordo com a metodologia proposta pelo Instituto Joanna Briggs para responder à pergunta norteadora Quais os possíveis usos da ultrassonografia por enfermeiros do bloco operatório? Os artigos foram buscados nas principais bases internacionais de literatura científica e cinzenta. Os descritores utilizados serão ultrassonografia e centros cirúrgicos. A pesquisa se orientou pelo acrônimo P-C-C: P – Participantes: Equipe de Enfermagem do Centro Cirúrgico; C – Conceito: Ultrassonografia; C - Contexto: Centro Cirúrgico. Registro do protocolo: osf.io/p8zne. Resultados: Os estudos encontrados versavam sobre três usos principais da ultrassonografia para enfermeiros perioperatórios no cenário do bloco operatório: avaliação gástrica (N=7), avaliação de conteúdo vesical (N=10) e auxiliar para punção periférica venosa e arterial (N=3). Conclusão: Os enfermeiros perioperatórios devem buscar formação para práticas avançadas incluindo o uso de ultrassonografia como auxiliar na sua prática.
Perspectivas para a Prática Avançada de Enfermagem em Unidades de Terapia Intensiva: Uma Reflexão
Authors: Oliveira Hudson Carmo de , Rocha Ticiane Cardozo , Melo Yasmim Pacheco Silva de , Cruz Lucas Saldanha , Henrique Danielle de Mendonça , Camerini Flávia Giron
Published: February 2024

Objetivo: Refletir sobre as ações de práticas avançadas de enfermagem no contexto das Unidades de Terapia Intensiva. Método: Trata-se de um estudo teórico-reflexivo embasado em literatura internacional, cujos artigos apontem ações do enfermeiro de prática avançada no ambiente de terapia intensiva, além do guideline de Prática Avançada de Enfermagem do International Council of Nurses. Resultados: A união de informações acerca das ações de práticas avançadas de enfermagem no ambiente de terapia intensiva permitiu a reflexão que gerou nove categorias de ações: educação continuada, educação em saúde, ser referência especializada em terapia intensiva, atividade de pesquisa, gerenciamento do cuidado, liderança de equipe, cuidado com a família, atuação em equipe multidisciplinar e assistência direta ao paciente. Conclusão: A reflexão evidenciou que educação, gestão e assistência são eixos de competências encontradas nas práticas avançadas de enfermagem na terapia intensiva.
Application of hydrogel scaffolds as a cell substrate for cartilage tissue regeneration
Authors: Golubinskaya Polina  A. , Pikina Arina S. , Ruchko Eugene S. , Vladimirova Tatyana V. , Bogomazova Alexandra N. , Eremeev Artem V.
Published: February 2024

Cell therapy or tissue engineering is currently one of the potentially effective strategies for repairing cartilage defects. Mesenchymal stromal cells and autologous and allogeneic chondrocytes obtained from cartilage biopsies from patients undergoing arthroscopic surgery are the most commonly used cells for tissue engineering. Matrices (scaffolds) often used during cell implantation can facilitate successful cell implantation. These can be static supporting or plastic hydrogel substances obtained by various methods from natural or synthetic materials, allowing cells to be delivered to the site damaged by injection. Significant advantages of biocompatible hydrogels in cartilage injury therapy are determined based on the properties of the natural extracellular matrix and the high plasticity required for adapting to irregular surfaces of the tissue defect and allowing injectable cell delivery. These characteristics make injectable hydrogels a promising tool for cartilage bioengineering.
This study highlights the progress in injectable hydrogels as carriers of different cells in the repair of cartilage tissue defects, as well as the current requirements and unresolved issues related to the use of such therapeutic approaches.
Bacterial vaginosis as a factor associated with adverse pregnancy outcomes
Authors: Oganyan Kristina A. , Krysanova Anna A. , Savicheva Alevtina M. , Bespalova Olesya N. , Kogan Igor Yu.
Published: February 2024

Bacterial vaginosis is the most common disease of the genitals and affects 20–70% of women. This non-inflammatory syndrome is characterized by dysbiosis of the vaginal microbiota and is accompanied by a decrease in the number of lactobacilli. Bacterial vaginosis in 60% of pregnant women is asymptomatic, but can lead to obstetric complications such as late miscarriage, premature birth, fetal growth restriction, premature rupture of membranes, choriominionitis, postpartum endometritis, and sepsis. The clinical picture of bacterial vaginosis in pregnant women is the same as in non-pregnant women, namely homogeneous whitish-gray discharge from the genital tract, often with an unpleasant “fishy” smell, rarely itching and/or burning in the genital area and urethra, as well as soreness during urination (dysuria), with no signs of an inflammation detected in the genitals. Diagnosis of bacterial vaginosis in pregnant women, as well as in non-pregnant women, is based on the use of clinical and laboratory methods. Multiplex tests based on the nucleic acid amplification method, such as real-time polymerase chain reaction, are very popular for the diagnosis of bacterial vaginosis in this country. The Femoflor-16 Reagent Kit (DNA Technology CJSC, Moscow, Russia) is designed to detect the DNA of opportunistic microorganisms, lactobacilli DNA and human genomic DNA (as a control for taking biological material). Examination of pregnant women, especially in case of complaints of vaginal discharge, should be carried out when registering for pregnancy in order to start treatment early and prevent adverse pregnancy outcomes for the mother and fetus. Biofilms formed by microorganisms in bacterial vaginosis, especially G. vaginalis, limit the penetration of antibacterial agents to bacteria, their concentration being lower than therapeutic one, which leads to ineffective treatment. There remain many unexplored issues related to changes in the epidemiology of bacterial vaginosis, an increase in the frequency of relapses against the background of increasing resistance of microorganisms associated with bacterial vaginosis to antibiotics, and the development of agents that affect bacterial films.
Blood oxytocin levels and the rs4686302 polymorphism of the oxytocin receptor gene in patients with adenomyosis
Authors: Netreba Elena A. , Yarmolinskaya Maria I. , Malysheva Olga V. , Shalina Maria A. , Tkachenko Natalia N. , Koloshkina Anastasia V.
Published: February 2024

BACKGROUND: An in-depth study of the pathogenesis of adenomyosis and the development of new therapeutic approaches are extremely relevant. Atosiban, a competitive oxytocin receptor antagonist, may be a promising drug with a potential therapeutic effect. Oxytocin is involved in the pathogenesis of adenomyosis-associated dysmenorrhea, and there is evidence of increased expression of the oxytocin receptor (OXTR) in the myometrium in adenomyosis and the association of the OXTR gene polymorphic variant rs4686302 with oxytocin-induced myometrial contractility.
AIM: The aim of this study was to evaluate blood oxytocin levels and the frequency of the polymorphic variants of the oxytocin receptor gene (OXTR) rs4686302 polymorphism in patients with adenomyosis and in healthy women of reproductive age.
MATERIALS AND METHODS: The levels of oxytocin in the blood plasma were measured by competitive enzyme immunoassay (ELISA) in patients with adenomyosis (n = 56, with mean age of 37.5 ± 8.54 years), and in women without gynecological diseases (control group; n = 33, with mean age of 32.1 ± 5.40 years). The polymorphic variant rs4686302 of the OXTR gene was analyzed by PCR-RFLP analysis in patients with adenomyosis (n = 79, with mean age of 39.9 ± 7.74 years) and in control group patients (n = 49, with mean age of 37.0 ± 9.20 years). The chi-square (χ2) test was used to analyze the distribution of genotypes and alleles. Statistical data processing was performed using the Jamovi Software, Version 1.2.27 for Windows.
RESULTS: In patients with adenomyosis, the level of oxytocin in the blood serum was significantly higher than in control group patients: 130.0 ± 27.9 pg/ml and 95.9 ± 26.7 pg/ml, respectively. The minor allele A of the OXTR gene polymorphic variant rs4686302 was significantly more common in patients with adenomyosis (28.5%) than in women in the control group (13.3%) and in the general sample (11–15% according to the 1000 Genomes Project). The odds of developing adenomyosis in patients with the presence of the A allele (the G/A and A/A genotypes) were 2.44 times higher compared to patients with the G/G genotype (OR 2.44, 95% CI 1.13–5.28).
CONCLUSIONS: The data obtained suggest the participation of oxytocin and its receptor in the pathogenesis of adenomyosis and requires further research in this direction.
The role of microRNAs in preeclampsia
Authors: Postnikova Tatiana B. , Vashukova Elena S. , Glotov Andrey S. , Mozgovaya Elena V. , Pachuliia Olga V. , Bespalova Olesya N.
Published: February 2024

AIM: The aim of this study was to review current sources of scientific literature covering the role of miRNAs in preeclampsia.
BASIC PROVISIONS: MicroRNAs are a class of short RNA nucleotide sequences that are not involved in protein synthesis, but are capable of controlling complex processes such as cell growth, differentiation, stress response, and tissue remodeling, which under certain conditions play a key role in a variety of pathological processes, including preeclampsia. MicroRNAs regulate up to 60% of the human genome. There are three types of placental miRNAs: placenta-specific, placenta-associated and circulating ones. Three miRNA gene clusters, namely chromosome 19 cluster (C19MC), chromosome 14 cluster (C14MC), and miR-371 ~ 373 cluster, encode most placenta-specific miRNAs. C19MC encodes 58 mature miRNAs and is expressed in trophoblast cells in early pregnancy and then, in placental differentiated cells. C14MC encodes 63 mature microRNAs, which are also expressed in trophoblasts. The miR-371~373 cluster only encodes six mature microRNAs expressed in placental differentiated cells and embryonic stem cells. The functions of placenta-specific miRNAs are being actively studied now. It has been established that the action of these microRNAs is associated with proliferation, apoptosis, migration, angiogenesis of trophoblast cells and placentation in early pregnancy. Recently, special attention has been paid to identifying microRNAs as possible predictors of preeclampsia in early pregnancy.
CONCLUSIONS: Literature data indicate that miRNAs are associated with the pathogenesis of preeclampsia. It has been proven that more than a hundred types of miRNAs are expressed in placental tissues, and some of them can be isolated and detected in peripheral blood and urine in patients with preeclampsia. Studying the miRNA types will allow for determining the most significant prognostic markers for early detection of preeclampsia and developing non-invasive tests.
An improved method for experimental modeling of premature ovarian insufficiency in Wistar rats
Authors: Zakurayeva Karina A. , Yarmolinskaya Maria I. , Adamenkov Nikita A. , Potapova Elena V.
Published: February 2024

BACKGROUND: Despite an enormous progress in the field of reproductive endocrinology, the mechanisms of premature ovarian insufficiency have not been fully understood so far. Knowledge of the supposed causes and mechanisms underlying the development of premature ovarian insufficiency has expanded significantly in recent years, mainly due to advances in genetics and the creation of models for experimental research. The experimental modeling of premature ovarian insufficiency, which is as close as possible to the origin and development of the corresponding disease in humans, is effectively used to elaborate promising therapeutic approaches, in particular, to test new drugs or biologically active agents in order to study their preventive or curative effects. This article discusses the main methods of the experimental modeling of POI in laboratory animals. We have herein summarized the literature data related to the development of the clinical and morphological picture of the disease, with the advantages and disadvantages of each of the models analyzed.
AIM: The aim of this study was to modify the premature ovarian insufficiency modeling methodology to substantiate the effectiveness and to test new directions in drug therapy with subsequent implementation in clinical practice.
MATERIALS AND METHODS: The new method is based on the creation of an experimental premature ovarian insufficiency model in female Wistar rats. To obtain this model, experimental rats were randomized into two groups: 1) animals receiving cyclophosphamide at a dose of 150 mg/kg b.w. subcutaneously once (n = 10); 2) animals receiving 2 ml of saline intraperitoneally once (n = 9). On day10, the animals were removed from the experiment. After autopsy, a visual assessment of morphological changes in the ovaries was carried out, and a right-sided ovariectomy was performed.
RESULTS: When using the proposed model, the reproducibility rate of POI has reached 100%.
CONCLUSIONS: Our modification of the method ensures the creation of a highly reproducible premature ovarian insufficiency model in Wistar rats. Another significant advantage of this modeling method is its ease of implementation and economic efficiency.