bluuebunny/crossref_metadata_2025 huggingface dataset:
Developing a Tourism Strategy for Heritage Villages in the Kayutangan Area
Authors: Insani N , Ariani Y , V K Ningrum E , R A'rachman F
Published: October 2022

The development of tourism in Malang is expanding, supported by the increasing number of tourists. To answer the growing demand of tourists, local governments should innovate with thematic villages. One such village that elevates historical and cultural values is the Kayutangan heritage tourism village, located in the Kayutangan corridor area in Basuki Rahmat Street, Malang City. The city’s image plays a role as an identity-maker and adds to the attraction in the development of the city area. For a long time, the image of Malang, especially the Kayutangan corridor, has been rich in cultural heritage from the Dutch colonial period. The typical Dutch colonial architectural style can be seen in government buildings, shops, and settlements in urban spatial plans developed to this day. However, loss of ownership resulting in the transfer of buildings to new owners, who then renovate the buildings with a more modern design, means that the number of buildings with historical value is decreasing. Furthermore, the empty and renovated buildings can negatively affect the visual appearance of the physical environment and the spatial character of the area, reducing the aesthetic quality. This study aimed to describe the elements that form the image of the city in the Kayutangan area, which can then be used in developing a tourism development strategy in the Kayutangan heritage area. The results of this study indicated a unique development opportunity that focuses on image-forming elements consisting of paths, edges, districts, nodes, and landmarks. Changes in the shape of the buildings are increasing, thereby reducing the aesthetic value of the area. Based on the SWOT analysis results, the elements forming the existing city image need to be optimized as part of a strong aesthetic identity in the Kayutangan heritage tourism village area. The elements forming the existing city image, if developed thoughtfully, can become a brand for the city and lead to an increase in local tourism.
Keywords: urban environment, city image elements, tourism development strategy
Preservation of Vegetation Diversity to Maintain the Riparian Ecosystem of the Sampean Watershed
Authors: Sumarmi Sumarmi , Indit Pakarti Titah , Fildzah Puteri Destari Luqyana , Aini Nurul , Tanjung Ardyanto
Published: October 2022

Riparian vegetation on river borders can affect the riparian ecosystem of the watershed related to its function as a buffer zone and ecotone between water and land. A high diversity of riparian vegetation can indicate that the ecosystem of a river border is in good condition. Therefore, it is helpful to inventory the diversity of vegetation in the riparian zone, which was done in this study using the Shannon-Wiener diversity index. In this research, four plots measuring 5m x 5m, spread across upstream, middle, and downstream areas were used to analyze the types of vegetation, including trees, shrubs, and herbs. The diversity index (H’) results revealed four vegetation species at the tree level, twelve species at the shrub level, and six species at the herb level. The range of H’ values in all sample plots was 1< H’ <3, so the river border was shown to have moderate diversity, which indicated that the ecosystem in the Sampean watershed is relatively balanced. It is necessary to preserve the riparian buffer zone through riparian vegetation restoration management to improve the ecosystem balance of the Sampean watershed.
Keywords: riparian vegetation, watershed, Shannon-Wiener diversity index
Identification of Subsurface Materials in Landslide-Susceptible Areas in the Pacet-Trawas Road Corridor Using the Geoelectrical Resistivity Method
Authors: Irawan L Y , H Pradana I , Panoto D , C Darmansyah A
Published: October 2022

Landslides are caused by changes in the structure of subsurface materials on steep slopes due to weathered rock conditions and soil pores in saturated conditions. This study used the geoelectric resistivity method to identify the type and structure of subsurface materials in landslide-susceptible areas in the Pacet-Trawas road corridor, in Pacet District, Mojokerto Regency. The research location was an area with undulating to mountainous morphology. The geoelectrical resistivity configuration used was dipole-dipole with a measuring path length of 100 meters at three measurement points. The measurement location was based on geological formations and the distribution of landslide points along the Pacet-Trawas road corridor. The three 2D models produced showed resistivity values between 8.11 Ohm.m to 390 Ohm.m. The subsurface materials consisted of groundwater, volcanic breccia, lava rock, tuffaceous breccia, conglomerate, and andesite-basaltic at a depth of 1.5 meters to 25 meters below the ground surface. The research area was dominated by the parent rock structure of lava, volcanic breccia, basalt, and andesite. Locations with a high landslide threat were located at points two and three with subsurface materials of the conglomerate type and volcanic breccia.
Keywords: geoelectrical resistivity, dipole-dipole, subsurface material
Geomorphological Mapping for Land Suitability Evaluation
Authors: Y Irawan L , E Prasetyo W , M R Devy M , Ditian Ditian
Published: October 2022

Geomorphology affects the potential of land. The geomorphological condition of an area has implications for physical characteristics, including: 1) type; 2) material; and 3) processes formed upon it. Understanding land capability allows for the evaluation of land suitability. Classification of land suitability is carried out by combining the results of land capability identification with requirements for plant growth or existing land use. Evaluation of land suitability can be done using the survey method. This study aimed to assess the suitability of land in Sumbersuko Village in Wagir District, Malang Regency. Land suitability was evaluated by matching the characteristics of the land with the land suitability class. This study used primary data taken from the regional morphology survey. Secondary data included: 1) digital elevation model data; 2) geological maps; 3) maps of soil types; and 4) Sentinel-2A images. The data from the field survey were then compiled using a geographic information system into maps using 2D and 3D modeling. The results of GIS analysis showed that Sumbersuko Village has six landform units, namely M1V1, M1V2, H2V2, U2V2, P2V2, and M3V3. Analysis of land capability and suitability of the six land units in a row gave the following results: 1) forest (highly suitable/S1); 2) forest and industry (suitable/S2); 3) plantation/agrotourism (moderately suitable /S3); 4) agriculture (not suitable/N); 5) residential area (less suitable/S3) S4); and 6) forest (highly suitable/S1).
Keywords: scientific, approach, methodological, techniques, geography
No Space at Home: Gender Ideology and Livelihood in Environmental Forced Migration
Authors: Anggaunitakiranantika Anggaunitakiranantika
Published: October 2022

The lives of women who have decided to become Indonesian migrant workers in several Asia Pacific areas, such as Singapore, Hong Kong, Taiwan, and South Korea, provide fascinating research opportunities. This research took as a case study several women from East Java Province who chose to become Indonesian migrant workers due to the loss of agricultural land or plantation fields as their main livelihood. The research analyzed the phenomenon of the migration of women as a result of the environmental crisis, which is a crisis specific to rural areas, as well as the gender ideology that accompanies the phenomenon of feminized labor in Indonesia. This research was conducted with a qualitative paradigm using the snowball technique for recruitment. The research location was in Banyuwangi Regency, East Java Province, Indonesia. The results of the research revealed that in the agricultural sector, which is a source of livelihood, land productivity continues to diminish due to famines, climate change, and land conditions that are not strategic and are progressively narrowed due to industrialization. Instead, land as an agricultural asset can be turned into cost capital for villagers, specifically women, to discover better jobs by migrating as Indonesian migrant workers. In carrying out international migration, the women attempted to alter the gender ideology, transform various negative stereotypes and become empowered and independent female workers.
Keywords: environmental, forced migration, gender ideology, livelihood
Utilization of Historical Sites as a Learning Source Based on Outdoor Learning
Authors: Djoko Sulistyo Wahyu , Nurfahrul Lukmanul Khakim Moch. , Kurniawan Bayu , Izam Masroir Muchammad
Published: October 2022

History learning should be a serious concern in the world of education. In practice in the field, especially at the high school level, it is very difficult to achieve the planned indicators, goals and competencies of history learning. Moreover, if history learning takes place in the classroom, the learning activities of students may be less effective compared to other learning, and the students may be less than optimal in participating in their learning. Therefore, this article offers an alternative solution by utilizing local historical sites as learning resources. The research model used was the historical method for the content of the historical material and the qualitative model for the preparation of learning schemes. Given the many abandoned historical sites around us, this article explores the use of the Cunggrang Inscription as a learning resource with activities based on outdoor learning.
Keywords: learning history, learning Resources, outdoor learning
Environmental Education at Adiwiyata Schools and the Conservation of the Brantas Watershed in Indonesia
Authors: . Abdul Kodir , Syaifulloh Mochammad , Indari Monassa Indhit , Sumarmi Sumarmi , Zubaidah Siti
Published: October 2022

In Indonesia, the Adiwiyata schools’ development program has implemented environmental education. These schools have a responsibility to preserve the environment, especially around school grounds. One of the elements of the Adiwiyata schools’ conservation program is the conservation of the Brantas watershed area which is currently experiencing degradation due to human activities. This study aimed to explain how environmental education in schools contributes to students’ knowledge, and to examine the efforts made by the Adiwiyata schools in the conservation of the Brantas watershed area. This research used quantitative and qualitative research methods. The quantitative method was carried out through a survey of 254 students at Adiwiyata schools through an online questionnaire. Qualitative data were collected through observations of school programs and policies as well as semi-structured interviews with teachers, students, and principals. The results of this study indicated that environmental education in Adiwiyata schools contributes to strengthening students’ cognitive and affective competencies towards the conservation of the Brantas watershed but not yet in the psychomotor domain. The Brantas watershed conservation efforts carried out by the Adiwiyata schools consist of monitoring river water quality, restoring riverbanks, and cleaning the river from pollutant waste. The realization of these efforts is the result of collaboration between the school and external parties, namely the Environment Agency, Jasa Tirta, the Tunas Hijau NGO, and the JKPKA Organization.
Keywords: environmental education, Adiwiyata, Brantas watershed, conservation, senior high school
Developing Teaching Materials Using STEM on Population, Human Development Index, and Demographics
Authors: Putra A K , Pratisia T , S Sumarmi
Published: October 2022

It is important in 21st-century learning to develop learning materials in digital form and teaching activities that require students to develop critical thinking, communication, creativity, and collaboration skills. 21st-century learning involves student-centered learning, where students are required to be more independent. Analysis of the needs of grade XII IPS 2 students at SMAN 2 BATU showed that the students needed interactive digital-based learning materials to support them, especially materials on the population, human development index (HDI), and demographics. This research therefore aimed to produce these digital learning materials using STEM (science, technology, engineering, mathematics) approaches. The ADDIE model was used, and qualitative and quantitative data were collected. Data were analyzed using percentage analysis techniques. The digital learning material products prepared were tested on 20 students of grade XII IPS 2 at SMA Negeri 2 Batu. Their validation was tested by material experts and media experts, obtaining validity values of 96% and 98%, respectively, which could both be classified as ‘very valid’. Furthermore, an eligibility test was carried out with geography teachers and students, and a result of 91% was obtained, which could be classified as ‘very feasible/very interesting’. Based on the results, it is feasible to use the STEM-based digital learning materials of population, HDI, and demographics effectively in geography learning.
Keywords: development, digital teaching materials, geography, STEM
Youth Adaptation in Transformation of Plantation and Agricultural Land on Sebatik Island
Authors: Harda Pratama Meiji Nanda , Hesti Gita Purwasih Joan , Subekti Arif
Published: October 2022

Studies at the border between Indonesia and Malaysia have not received much attention due to geographical factors and neglect on the part of the Central Government. One such area is on Sebatik Island, directly adjacent to Malaysia. Therefore, this study was developed to fill the gap in border studies, by explaining border dependence on neighboring countries. This dependence can be seen through the adaptation strategies of youth who work in the agricultural and plantation sectors in the Sebatik region. Qualitative methods with a case study approach were used. Data were obtained through observations, in-depth interviews, and secondary data analysis. Youth were the main informants; however, we also interviewed stakeholders in the Sebatik area, such as owners of agricultural land and plantations in Sebatik. The results showed that the Sebatik border community depends on Malaysia for trade and thus the agricultural and plantation aspects in the region are oriented to the needs of Malaysia. This ultimately impacts young people, especially those who work as manual laborers, to adapt to changing crops on plantations in Sebatik.
Keywords: border, youth, Sebatik, plantation, agricultural
Social Capital Based on Local Ecological Knowledge in the Bompon Watershed Community
Authors: Kurnia Putra Alfyananda , Bekti Susetyo Bigharta , Daeng Ngimba Samsunardi
Published: October 2022

Environmental ethics has an important position in the management and utilization of the environment; however, the paradigm of human interaction with the environment often creates gaps in ethical understanding. A range of negative impacts arise as a result of imperfect interactions between humans and the environment. Individuals and communities should focus on achieving sustainable environmental development. One such development is through social capital based on local ecological knowledge (LEK). The purpose of this study was to identify and describe a community of social capital based on LEK in accordance with the environmental ethics of the Bompon watershed community in Magelang Regency. We used qualitative descriptive methods; data were collected using interviews and observations. The results showed that social capital based on LEK in accordance with basic environmental ethics referred to experience, trust, adherence to values, regulations, and institutions in the Bompon watershed community.
Keywords: Bompon Watershed Community, environmental ethics, local ecological knowledge
Work Sustainability: Challenges of Employment Environments for Factory Workers
Authors: Anggaunitakiranantika Anggaunitakiranantika , Lailiyah Hanum Nur Aini
Published: October 2022

When factory industrial development occurs in a region, people’s livelihoods shift from the agrarian to the industrial sectors. The factory industry makes job opportunities available to people from all walks of life. The purpose of this research was to identify the strategies employed by factory workers to ensure their own survival. The study used qualitative descriptive methods. Research was conducted in Mojokerto Regency, Indonesia. The research used observations, interviews, and documentation. The findings were as follows: (1) survival mechanisms used by factory workers to meet their own needs are very diverse. They include doing side work, bringing family members to work, borrowing money from friends and cooperatives, and saving money for family expenses. They are all done to meet their own needs. (2) Workers’ attempts to keep working are carried out by operating various machines, demonstrating the best work abilities possible, following factory rules, and attempting to win the approval of superiors so that their employment contracts might be extended. They act in order to be able to survive in competition with other factory workers.
Keywords: factory workers, job opportunities, Mojokerto Regency, needs fulfilment
Spatial Analysis of Temperature Changes in Batu City Due to Land Conversion in 2015-2020
Authors: Sumarmi Sumarmi , Idham Akmalani Muhammad , Regita Cahyaning Putri Nanda , Nila Ziyana Cholidah, Nina , Tanjung Ardyanto
Published: October 2022

Batu City has positioned itself as a center for organic agriculture based on international tourism, and, consistent with its vision in the Batu City Regional Spatial Plan for 2010-2030, the city will become a City of Tourism and Agropolitanism in East Java. From 2015 to 2020, Batu City increasingly developed, especially its tourism sector. The increased number of Batu City tourism sites indirectly illustrated changes in land use. The availability of relatively fixed land is not directly proportional to the high demand for land use and the decreasing vegetation cover. This has led to changes in land use and temperature. This research on temperature changes due to land conversion was carried out in Batu City, East Java. The research design employed Landsat 8 OLI/TIRS image processing using land surface temperature, the normalized difference vegetation index (NDVI), and the normalized difference built-up index (NDBI). The results showed a relationship between land conversion and temperature changes in Batu City, where there was a change in the land surface temperature interval in 2015-2020. Temperature changes were caused by conversion of forest into agricultural land and built-up land. Vegetated land areas were also converted, so land with dense and moderately dense vegetation decreased. The dense vegetation decreased from 3,757 hectares to 3,437 hectares, while the moderately dense vegetation decreased from 7,867 hectares to 7,531 hectares. Conversely, the sparsely vegetated land increased from 7,463 hectares to 8,117 hectares.
Keywords: land surface temperature, land conversion, Batu City
Afeto e subversão: Práticas infantis nos percursos cotidianos entre casa e escola em Rio das Pedras/RJ
Authors: Pereira Mariana , Arteiro Nielsen Azevedo Giselle
Published: October 2022

Tendo como perspectiva a invisibilidade das infâncias na participação e decisões sobre os lugares que utilizam na cidade, o artigo propõe um exercício de reflexão sobre como as crianças experienciam e, com isso, subvertem seus espaços livres cotidianos, ativando, reformulando e transformando a paisagem. Tendo como área de estudo o bairro de Rio das Pedras, o percurso metodológico foi estruturado na relevância do pesquisar-COM, por meio de uma abordagem qualitativa, que utiliza como base o acervo de narrativas de estudantes matriculados no Ensino fundamental de escolas públicas do Rio de Janeiro, apreendidas na atividade “Mapeamento Afetivo dos Territórios Educativos da Cidade do Rio de Janeiro” (GAE;SEL, 2020, onde procurava-se identificar as percepções e desejos das crianças, sobre seus percursos cotidianos de casa à escola. Os resultados obtidos nesta leitura sensível do território colaboram com uma visão real sobre a qualidade espacial urbana e o direito à cidade, por um olhar atento às micropolíticas do cotidiano e a construção da cidadania das infâncias que habitam este território.
Training of future teachers about educational technologies of vocational training
Authors: Kamalov Murat , Saipov Amangeldi , Kamalov Yusubali
Published: October 2022

This study aimed at investigating the education of future teachers about the educational technologies of vocational education, and it was designed according to this purpose. In this context, it was aimed to conduct a study with the teachers of the future. The research was created and implemented in the 2021–2022 spring academic year. A total of 172 pre-service teachers voluntarily participated in the research. In the research, vocational education technologies were given with the help of online technology in the form of a 2-week online training to the group participating in the study. In order to collect data in the study, the ‘Vocational Education and Technology’ data collection tool, which was developed by the researchers and whose validity and reliability were obtained, was used. The data collection tool used in the research was delivered to the people participating in the research with the Google survey method and collected. The analysis of the data was made by using the Statistical Package for the Social Sciences programme, frequency analysis and t-test; the results are added to the research in the presence of tables. As a result of the research, it is seen that the teachers of the future will prefer technology for vocational education and use it in their professional life to achieve positive results.

 

Keywords: Teachers of the future, vocational education, online and distance education, technology;
30 Years Journey of KSTEL: Achievements and Prospect of Teaching English Drama
Authors:   The Korean Society For Teaching English Literature, Park Jungman
Published: October 2022

The Korean Society for Teaching English Literature (KSTEL), founded in August 1992, celebrates its 30th anniversary this year in 2022. At this point, it will be meaningful to look back and reflect on the past journey of KSTEL and to anticipate and prepare for the future. For this purpose, ‘archiving’ academic achievements of KSTEL so far is a course that must be taken in preparation for the future, and will be a necessary step at this moment of time when the past and the present meet and, at the same time, the present encounters the future. This paper aims to survey the ‘English drama education’ articles published in The Journal of Teaching English Literature of KSTEL from the first issue in 1996 to the 2021 winter issue, and to track changes and trends in pedagogy as well as research methodology and themes during the period. In addition, while commemorating the 30th anniversary of KSTEL, it also intends to serve the purpose of ‘archiving’ the scholarly research and achievements in English drama education papers published in The Journal of Teaching English Literature, as a work of looking back on the past journey of KSTEL and subsequently creating a map for future travel.
English Garden in English Novel
Authors:   The Korean Society For Teaching English Literature, Choi Jungsun
Published: October 2022

This essay tries to prove that an English novel is a good textbook, in teaching English Garden, one of the major English cultural issues. English Garden, specifically, English Landscape Garden or Picturesque Garden is a critical issue in that it contributed to forming English Identity as rural England in the period of Industrial Revolution and Enclosure. To achieve that goal, it first examines the ideas and major characteristics of eighteenth century English Garden, including Lancelot Brown’s picturesque landscape design which was very popular from mid-eighteenth to the late eighteenth century in England. Next, it searches the descriptions of Landscape Garden in Jane Austen’s Pride and Prejudice, which is set in rural England in the late eighteenth century. Lastly, it connects the characteristics of Brown’s Landscape Garden, main features of which are spontaneity, naturalness, emphasis on sentiments and the symbol of liberty to the representation of the novel’s main characters, Elizabeth Bennet and Fitzwilliam Darcy, and their change and growth.
Dozhin rituals in the system of traditional culture of the Eastern Slavs: ethnolinguistic components in semiotic analysis aspect
Authors: Andreeva Olga N.
Published: October 2022

We pay particular attention to the consideration of semantic components of the dozhin ritual (“beard curling” ritual) as an ethnolinguistic text, which are the ontological foundations of the agrarian complex of traditional culture system of the Eastern Slavs. We give a description of the “beard curling” ritual in the form of representation of actional blocks using the basic categories of semiotic analysis, an interpretation of the meaning of symbolic semiotic structures in the form of a layout of symbolic components. The field materials presented by us are both an indicator of the All-Russian context and the specific area itself – the Central Black Earth Region, in particular, Tambov region, and demonstrate the echoes and originality of functioning of constituent compo-nents of the dozhinochny ritual. The texts of this rite, incantatory elements, actional components turn out to be quite many-sided and diverse. The explanation of ritual’s ethnolinguistic compo-nents in the folk environment shows how the people interpret the contexts of its origin and devel-opment. The actual symbolic representation is shown in the sacred context of all symbolic semes, which emphasizes their ontological nature. The sacredness of the ritual is represented in the sym-bolism of significant semes: the “beard” in this case is an ethnolinguistic metaphor for the Chris-tian appeal to God, a prayer for the future harvest.
“The main drawback of the book originates from its main advantage”: the evaluation strategy of polarity compensation in the reviews of German and Russian linguists
Authors: Kondratenko Polina I.
Published: October 2022

The purpose of the study is to analyze clusters of statements embedded in the evaluative strategy of polarity compensation in German and Russian academic reviews in Linguistics. Moreover, the article is aimed at identifying linguistic and cultural differences determining the usage of this evaluative strategy. The most typical feature established for the strategy under consideration roots in the balancing positive and negative assessments. For the first time, the analysis takes into account the variability of the polarity compensation strategy depending on specific patterns of the interaction between positively and negatively polarized assessments in clusters. The study carried out shows that the polarity compensation in evaluative acts accomplished in academic linguistic reviews can function as a macro-strategy of expert evaluation. Single assessments embedded in polarity compensation strategy can be implied as a recommendation, (dis)agreement with the author, proof by contradiction. The article describes the results of a comprehensive socio-communicative and discursive study of expert evaluation acts. Qualitative and quantitative analysis leads to description of the polarity compensation mechanism as well as to elicitation of lexical and grammatical means typical of this strategy. Interpretation of the statistical data processing allows us to draw conclusions about culturally specific trends in the use of the polar compensation strategy by German and Russian reviewers.
“Ah, what a glorious land...”: about the parody of V. Bakhnov against the backdrop of the pamphlet by A. Perventsev
Authors: Sviridov Stanislav V.
Published: October 2022

The object of research is Vladlen Bakhnov's parody song «Ah, chto za slavnaya ziemlya» (“Ah, what a glorious land...”), written as a response to Arkady Perventsev's pamphlet «Kuriny bog» (“Chicken God”). The purpose of the study is to identify the author's strategy of the parody text formation as a comic image of an object. The first printed publications of the texts under consideration are taken as the research material. The complex methodology of the work is based on a comparative method involving structural and historical-cultural methods. When discussing the issue, each of the studied works is considered separately. The analysis of the pamphlet by A. Perventsev makes it possible to identify the cultural prerequisites of the writer's speech and to characterize the genre-poetic specifics of the pamphlet. V. Bakhnov's parody as a “comic image of a work” is characterized taking into account the fact that the parody genre supposes the selection of poetic material: some constructive elements of the text-object are reproduced, others are ignored; others make up the “own” poetic series of the parodying work. It is established that the quotation plan of V. Bakhnov's song consists of theses, judgments and journalistic cliches of A. Perventsev, the symbolism of the pamphlet becomes the “missed” material. The “added” material is organized in a way atypical for the genre of parody – it reflects the poetic form of the thieves' song «Eh, kak vspomnish starinu» (“Eh, if you will remember the old days...”). In this regard, the genre of V. Bakhnov's work is defined as a parody rehash. The results of the research can be used in the preparation of courses on the history of Russian literature of the second half of the 20th century, special courses and seminars in higher educational institutions.
Modern trends in event marketing in promoting the university brand
Authors: Romashkin Viktor A.
Published: October 2022

We consider current trends in event marketing in relation to various areas. Event marketing is focused on building a strong emotional connection between brand and audience. As the practice of domestic and foreign universities shows, event marketing is in demand in promoting the brands of an educational institution. We present the most striking cases of special events of domestic and foreign universities. Despite the downturn in the special events market caused by the pandemic, special events are becoming more diverse in form (a hybrid special event format has been developed) and more original in content. In the university environment, there has been a trend towards a transition from narrowly corporate events to events focused on the widest possible audience, from traditional events (“First-Year Student Day”, “Student Spring Festival”) to branded events that characterize the university as a subject of the public life of the region. As examples of special events aimed at various audiences, the events of the Derzhavin Tambov State University (“Career Forum”, “First-Year Student Week”, “Derzhavin Mile”, “Derzhavin Regatta”, “Derzhavin Ski Track”).
Architectonics as a way of studying painting (on the example of M. Vrubel’s work)
Authors: Nikolskaya Tatyana M.
Published: October 2022

The main purpose of study is the issue of studying the work of painting with the help of architectonics. The definition of this term is given in a broad sense, which allows us to apply it not only to the study of architectural objects, but also gives us the opportunity to apply it to the fine arts, and also allows us to consider a painting at a higher quality level, taking into account many factors that contribute to its holistic perception, which is relevant today. We use semiotic method, which allows us to address such a fact as the perception of a work of art and the creation of one’s own artistic image. Analysis of some works by M.A. Vrubel allows us to draw a conclusion about his originality of thinking and the creative method used by the artist, with the help of which he tried to convey his vision to a wide audience. All these points that are touched upon: colour, composition, space, all this is a reflection of the artist’s inner intense work, his attempt to rethink reality, himself, in order to be able to explain this to “readers”. Such an approach allows not only to study the artist’s work, but also to consider the features of his perception of space, which in turn can be used in teaching humanitarian subjects, and will also attract a wider range of scientists dealing with the same kind of problem, and will continue the discussion. in this direction.
Enantioselective 1,1-diarylation of terminal alkenes catalyzed by palladium with a chiral phosphoric acid
Authors: Ji Kai , Huang Jie , Zhang Xin-Yu , Chen Zhi-Min
Published: October 2022

The enantioselective 1,1-diarylation of allyl sulfones and vinyl sulfones is reported for the first time, enabled by a combination of Pd2dba3 and a chiral SPINOL-derived phosphoric acid. Various chiral sulfones containing 1,1-diarylalkane motifs were obtained in moderate to good yields with moderate to high enantioselectivities. Control experiments suggested that the sulfone group plays a key role in providing enantioselectivity and reactivity control and might serve as a directing group.
Association of polymorphic variants of GRIN2A and GRIN2B genes with alcohol and tobacco abuse in patients with schizophrenia
Authors: Tiguntsev V. V. , Gerasimova V. I. , Kornetova E. G. , Fedorenko O. Y. , Semke A. V. , Kornetov А. N.
Published: October 2022

Aim. To compare the frequency of genotypes for polymorphic variants of GRIN2A and GRIN2B genes in patients with schizophrenia and addictive behavior (alcohol / tobacco abuse) and in patients with schizophrenia without addictive behavior in the Slavic population of the Tomsk region.

Materials and methods. The study included 219 inpatients with the established diagnosis of schizophrenia who received treatment in the clinics of Mental Health Research Institute and Tomsk Clinical Psychiatric Hospital. A history of alcohol / tobacco abuse was identified during a clinical interview and objective data collection. DNA was isolated from peripheral blood leukocytes by standard phenol – chloroform extraction.

15 single nucleotide polymorphisms (SNPs) in the GRIN2A gene and 9 polymorphisms in the GRIN2B gene were selected for genotyping. Allelic variants were determined by real-time polymerase chain reaction (PCR) with specific primers. The SPSS 17.0 software package was used for statistical data processing. The distribution of genotype frequency was assessed using the Pearson’s χ2 test with the Yates’ correction and the Fisher’s exact test.

Results. Significant differences in the allele frequency for the rs9788936 polymorphism in the GRIN2A gene (χ2 = 4.23, p = 0.04) and for the rs10845838 polymorphism in the GRIN2B gene (χ2 = 4.27, p = 0.04) were reveled between the groups of patients with and without alcohol abuse. It was found that the polymorphic variant rs8049651 of the GRIN2A gene had a clear association (F = 8.06, p = 0.029) with the development of tobacco addiction in patients with schizophrenia.

Conclusion. The study identified the association between alcohol abuse and the rs9788936 polymorphism in the GRIN2A gene and the rs10845838 polymorphism in the GRIN2B gene in patients with schizophrenia. The association between the rs8049651 and rs7190619 polymorphisms in the GRIN2A gene and the development of tobacco abuse in patients with schizophrenia was revealed.
Pathogen-specific molecular imaging and molecular testing methods in the prognosis of the complicated course of diabetic foot syndrome, the risk of amputation, and patient survival
Authors: Zorkaltsev M. A. , Zavadovskaya V. D. , Saprina T. V. , Zamyshevskaya M. A. , Udodov V. D. , Shestakov A. V. , Mikhailova A. A. , Loyko Yu. N. , Musina N. N.
Published: October 2022

The aim of this review was to provide extended information on current trends in the diagnosis of complicated diabetic foot syndrome (DFS), the most frequent and severe complication of diabetes mellitus, including hightech medical imaging methods and instrumental and laboratory predictors of the complicated course and risk of amputation in DFS.

The article provides an analytical review of modern publications over the past 5 years on diagnosis and therapy. Pilot data on the use of high-tech medical imaging methods, assessment of skin microbiota and ulcers in DFS, molecular testing methods in terms of predicting the amputation risk and survival of patients with DFS, as well as the effectiveness of biosensing systems have been systematized, summarized, and subjected to analytical evaluation.

The review provides an expert assessment of the capabilities of pathogen-specific molecular imaging using modern positron emission tomography (PET), single-photon emission computed tomography (SPECT), and highenergy radionuclides in bacterial infection to understand its pathogenesis, minimize diagnostic problems, improve antimicrobial treatment, and address fundamental and applied aspects of DFS. Literature data on the assessment of foot perfusion in diabetic patients with varying degrees of limb ischemia by hybrid technologies (SPECT / CT and PET / CT) and new modalities of magnetic resonance imaging (MRI) are also systematized, which contributes to new understanding of the response to revascularization, surgical shunting, and stimulation of angiogenesis within ischemic tissue, as well as potentially to healing of foot ulcers.

The review is aimed at substantiating a multidisciplinary approach in DFS, selection, development, and implementation of innovative strategies for diagnostic modalities to identify diabetic foot pathologies, and choice of an adequate method for treating and monitoring the results of therapy in the context of personalized medicine.
Complexation of fluoroquinolones with magnesium ions
Authors: Bakhtin V. M. , Izmozherova N. V. , Belokonova N. A.
Published: October 2022

Aim. To evaluate strength of magnesium ion complexes with levofloxacin and moxifloxacin.

Materials and methods. Complexation of levofloxacin, moxifloxacin, and reference ligands (ethylenediaminetetraacetate (EDTA), sodium citrate, and glycine) with magnesium ions in the range from 0.0 to 1.0 mmol / l was studied. The technique developed by the authors (patent RU 2680519 C1) was used to measure the rate of a model formation reaction of a magnesium phosphate coarse dispersion. Complexing activity of ligands was expressed in relation to EDTA activity and compared with the theoretical ion exchange equilibrium constants. The half maximal effective concentration (C50) calculated by the Michaelis − Menten equation was used to evaluate the dependence of the complexing activity on the dose.

Results. A correlation between the activity of EDTA, citrate ions, and glycine and the theoretical equilibrium constants (R = −0.87, p < 0.001) was found. In the range from 0.0 to 0.4 mmol / l, both levofloxacin and moxifloxacin showed a lesser complexing effect than EDTA (p < 0.001), and in the range from 0.6 to 1.0 mmol / l, their complexing effect was comparable (p > 0.050). The activity of fluoroquinolones did not differ at any concentration (p > 0.050), but moxifloxacin C50 (0.13 mmol / l; 95% confidence interval (CI) 0.11–0.15) was significantly lower than that of levofloxacin (0.22 mmol / l; 95% CI 0.19–0.26), (p < 0.001). Within the 0.4–1.0 mmol / l concentration range, the activity of levofloxacin was higher than that of citrate ions and glycine (p < 0.001). Complexing activity of moxifloxacin was higher than that of citrate ions within the range of 0.2–1.0 mmol / l, and in the range of 0.4–1.0 mmol / l, it was higher than that of glycine (p < 0.001).

Conclusion. The proposed method showed that the complexing activity of fluoroquinolones was close to that of EDTA and exceeded the activity of citrate ions and glycine. The complexation of fluoroquinolones may be associated with their ability to induce side effects associated with magnesium deficiency.
The effect of depressive disorder on the clinical presentation of coronary artery disease and five-year survival of patients after myocardial infarction
Authors: Nonka T. G. , Lebedeva E. V. , Repin A. N.
Published: October 2022

Aim. To assess the effect of depressive disorder (DD) on the clinical presentation of coronary artery disease (CAD) and five-year survival rate of patients with chronic CAD.

Materials and methods. The study included 79 patients with functional class II–III exertional angina who experienced myocardial infarction more than 6 months before. The patients were divided into two groups: group 1 (n = 45) consisted of patients with CAD and depression and group 2 (n = 34) encompassed patients with CAD without depression. The clinical presentation of CAD was assessed by the results of filling out the angina pectoris self-control diary and exertion tests. The presence and severity of DD were determined using psychometric scales, such as Hospital Anxiety and Depression Scale (HADS) and Beck Depression Inventory (BDI), and verified by the psychiatrist. Information about five-year survival was obtained via telephone interviews with the patients and their relatives.

Results. Patients with CAD and DD were characterized by more frequent episodes of angina pectoris during a week (10 [8; 14] vs 6 [4; 7], p = 0.000004), an increased demand for nitroglycerin (4 [0; 10] tablets vs 0 [0; 4] tablets, p = 0.001), and lower exercise tolerance (50 [25; 75] W vs 75 [50; 75] W (p = 0.06), 350 [250; 400] meters vs 435 [350; 500] meters (p = 0.01) than CAD patients without DD. The five-year survival rate was significantly lower in group 1 than in group 2 (69 [62; 72] vs 71 [68; 72] months (p = 0.04)), 35 (77.8%) vs 32 (94.1%) patients survived. In group 1, a greater number of deaths from cardiovascular accidents (10 (22.2%) vs 2 (5.9%)) was noted (log-rank test, p = 0.03).

Conclusion. In patients with CAD, associated depression results in aggravation of the clinical course of CAD and poor disease prognosis, which requires timely diagnosis and treatment of DD.
Application of K-Means for Clustering Based on the Severity of COVID-19 in Indonesian Private Hospitals
Authors: Deswiaqsa Kathina , Darmawan Endang , Sugiyarto Sugiyarto
Published: October 2022

In December 2019, coronavirus (COVID-19) caused by SARS-CoV-2 was first discovered in Wuhan, China. This virus has a high transmission rate and can be transmitted through droplets, airborne, and aerosols. The clinical manifestations are very diverse ranging from mild, moderate, and severe. Therefore, this study aims to conduct a clustering of the spread of the Covid-19 pandemic to facilitate the identification and handling. The method of the K-Means algorithm can be used as a method to obtain the desired clustering. The implementation and evaluation were conducted using RapidMiner tools and Davies Bouldin Index (DBI) respectively. Furthermore, the data sources by Kangdra (2020) were used with a total sample of 110 for the period March-June 2020. The results showed that the optimal cluster is located at k: 2 with a DBI value: 0,094 as the lowest value. Therefore, the cluster is strong since a smaller DBI value gives a better cluster. The clustering obtained is Cluster 1 and 2 with mild and moderate severity. The results are expected to facilitate a better zone identification of the COVID-19 severity level and rising people awareness.
Modeling the Proportion of Tuberculosis Cases in South Sulawesi using Sparse Least Trimmed Squares
Authors: Randa Trigarcia Maleachi , Tinungki Georgina Maria , Sunusi Nurtiti
Published: October 2022

The deadliest infectious disease in Indonesia is tuberculosis (TB), and South Sulawesi is one of the provinces that contributed the most tuberculosis cases in Indonesia in 2018 with 84 cases per 100,000 population. This study aims to identify variables that could explain the proportion of TB cases in South Sulawesi. The data used has many explanatory variables, and there are outliers. Sparse Least Trimmed Squares (LTS) analysis can be used to handle data that has many explanatory variables and outliers. The resulting sparse LTS model successfully selects and shrinks the variables to 14 variables only. In addition, based on the value of R2 and RMSE for the model evaluation, the sparse LTS shows satisfying results rather than classical LASSO. The government can focus on these factors if they want to reduce the proportion of TB cases in South Sulawesi.
Focused Analysis of RNFL Decay in Glaucomatous Eyes using Circular Statistics on High-resolution OCT data
Authors: Ali Md. Hasnat , Desai Meghana , Jammalamadaka Sreenivas Rao , Senthil Sirisha , Srinivas M.B. , Pyne Saumyadipta
Published: October 2022

Using the OCT platform, we can generate high-resolution data on retinal nerve fiber layer (RNFL) thickness in a given eye at a large number of angular-points defined on a circular coordinate system. However, insightful characteristics of OCT RNFL data such as its circularity and granularity generally remain unutilized in its common downstream statistical analyses. We present a new circular statistical framework that defines an Angular Decay function and thereby provides a directional representation of an eye in terms of its focused RNFL loss. By applying to a clinical cohort of Asian Indian eyes, the generated circular data was modeled with a finite mixture of von Mises distributions, which led to unsupervised identification in different age-groups of 2 recurrent clusters of glaucomatous eyes with distinct directional signatures of RNFL decay. New indices of global and local RNFL loss were computed for comparing the structural differences between these glaucoma clusters across the age-groups.
Catalytic Hydrolysis of Organophosphorus 1 Nerve Agents by Metal-organic Frameworks: What Happens Next?
Authors: Li Yunzhuo
Published: October 2022

Organophosphorus nerve agents are amongst the most toxic chemicals known to human beings. 9 They interfere with the central nervous system, resulting in continuous muscle contractions, 10 paralysis and even death. Prohibition by many countries around the world cannot disguise the 11 remaining presence of nerve agents in stockpile storage and governmental deployment, 12 highlighting the dire need for an efficient catalyst to degrade and detoxify nerve agents by 13 hydrolysis. Metal-organic frameworks (MOFs) have raised a few eyebrows for their permanent 14 porosity, precise tunability, and lasting stability. Modern Reticular Chemistry fosters the design and 15 synthesis of well-defined crystalline MOFs with open Lewis acidic metal sites that can catalytically 16 hydrolyze nerve agents both in aqueous solution and in solid state systems, unveiling unparalleled 17 potential for MOF-based personal protection gears. In this review, a summary of the representative 18 catalytically active MOFs in nerve agent hydrolysis is discussed. MOFs are categorized by their 19 reticular structure, emphasizing the capability and mechanistic insights of each single MOF in nerve 20 agent hydrolysis. The author’s perspective on the current challenges and future directions of MOF- 21 based catalysts in real-world protection applications is also provided, which hopefully could shed some 22 light on the future development of commercially available MOF protection suits.