bluuebunny/crossref_metadata_2025 huggingface dataset:
Curing process, mechanical property and thermal stability of acrylic polyurethane/Fe2O3 nanocomposite coatings
Authors: Vy Do Truc , Hung Dao Phi , Anh Nguyen Tuan , Lam Tran Dai , Vuong Nguyen Thien
Published: June 2024

The effect of Fe2O3 nanoparticles (NPs) on the curing and properties of acrylic polyol HSU 1168 based coating were investigated. The SEM images showed that Fe2O3 NPs with the content £ 2 wt.% were dispersed regularly in the polymer matrix. The obtained results indicated that Fe2O3 NPs slowed down the curing process of acrylic polyol coating. Without nanoparticles, the neat HSU 1168 based coating has completely cured after 96 hours, whereas in the presence of 2 wt.% Fe2O3 NPs in coating matrix it needed 120 hours for a full curing. In addition, the relative hardness of nanocomposite coating has reduced with increasing the Fe2O3 NPs content. Without nanoparticles, the relative hardness of neat acrylic polyol coating was 0.88, whereas it was 0.75 when 4 wt.% Fe2O3 NPs was added into the coating matrix. Besides, incorporation of Fe2O3 NPs into the acrylic polyol coating also enhanced its abrasion resistance and impact resistance with 2 wt.% Fe2O3 NPs being the best content (i.e. 200 kG.cm of impact resistance and 408.8 L/mil of abrasion resistance). On the other hand, incorporation of Fe2O3 NPs into the coating matrix improved its thermal stability. The starting temperature for degradation of nanocomposite coating (with 2 wt.% Fe2O3 NPs) was 15 oC higher than that of the neat coating (without nanoparticles)
A high-sensitivity hydrogen gas sensor based on Ag nanoparticle-decorated porous Co3O4 nanorods
Authors: Sinh Vu Hung , Quang Duong Tuan , Phuong Tran Quy , Hoa Tran Thai , Hieu Nguyen Van , Cuong Nguyen Duc
Published: June 2024

In this report, Ag nanoparticle-decorated cobalt carbonate hydroxide microflowers were synthesized using a simple hydrothermal approach without using surfactants, which were used as precursors to prepare Ag nanoparticle-decorated porous Co3O4 nanorods through an annealing process. The porous Co3O4 nanorods were composed of small primary nanoparticles with a size of ~ 10 nm, and their surface was decorated with uniform Ag nanoparticles (~ 10 nm). Sensors based on the porous Co3O4 nanorods decorated with Ag nanoparticles have higher sensitivity and selectivity to H2 gas than other reduced gases, as well as rapid response-recovery times. The enhanced H2 sensing properties of the sample may be attributed to the excellent catalytic features of Ag nanoparticles and unique porous Co3O4 nanorods. The results demonstrated the potential of Ag nanoparticle-decorated porous Co3O4 nanorods as sensing materials for the detection of hydrogen gas at low temperatures.
Preserving authenticity: transfer learning methods for detecting and verifying facial image manipulation
Authors: R Sheth Kịnal , S Vora Vishal
Published: June 2024

Facial retouching in supporting documents can have adverse effects, undermining the credibility and authenticity of the information presented. This paper presents a comprehensive investigation into the classification of retouched face images using a fine-tuned pre-trained VGG16 model. We explore the impact of different train-test split strategies on the performance of the model and also evaluate the effectiveness of two distinct optimizers. The proposed fine-tuned VGG16 model with “ImageNet” weight achieves a training accuracy of 99.34 % and a validation accuracy of 97.91 % over 30 epochs on the ND-IIITD retouched faces dataset. The VGG16_Adam model gives a maximum classification accuracy of 96.34 % for retouched faces and an overall accuracy of 98.08 %. The experimental results show that the 50 % - 25 % train-test split ratio outperforms other split ratios mentioned in the paper. The demonstrated work shows that using a Transfer Learning approach reduces computational complexity and training time, with a max. training duration of 39.34 min for the proposed model.
Potent inhibitory effect on human platelet aggregation of the aerial part of Canna edulis
Authors: Nguyen Thi Van Anh , Bui Duc Huy , Le Hong Luyen
Published: June 2024

Canna edulis Ker Gawl has been used in Vietnamese Traditional Medicine for the treatment of heart diseases with very limited scientific evidence. This study aimed to evaluate the inhibitory effect on human platelet aggregation of the aerial part of C. edulis. Aerial C. edulis was firstly macerated with methanol, and then fractionated with different solvents to obtain 3 fractions: n-hexane, ethyl acetate and aqueous extracts. The inhibitory effects on human platelet aggregation of extracts were evaluated via three parameters: percentage inhibition of platelet aggregation (%I), area under the aggregation curve (AUC) and aggregation slope, using two agonists adenosine diphosphate (ADP) and collagen. The results showed that all extracts significantly inhibited platelet aggregation in a dose-dependent manner for both agonists. Moreover, all extracts significantly decreased AUC and slope, indicating their antiaggregatory effects on both general aggregation and aggregation velocity. Among extracts, the ethyl acetate fraction exhibited the strongest effect regardless of agonists used (%I at 4 mg/mL, 99.2% for both ADP and collagen). The n-hexane fraction also had significant inhibitory effect but it was weaker than the others (p < 0.05). This is the first study to demonstrate the potent antiplatelet effect of the aerial part of C. edulis. This plant could be a potential natural source for searching novel antiplatelet agents and developing dietary supplements for management of cardiovascular diseases.
USE OF FERMENTED ACID WHEY ENRICHED WITH MINERAL ELEMENTS IN THE TECHNOLOGY OF RYE-WHEAT BREAD
Authors: Vysotskyi O. , Kochubei-Litvinenko O. , Bilyk О. , Bilokhatniuk V.
Published: June 2024

This article investigates the use of fermented acid whey enriched with mineral elements (magnesium, zinc, and manganese) in the technology of rye-wheat bread. Whey obtained through thermal acid coagulation of milk is a valuable resource that can significantly enhance the quality and nutritional value of bakery products. The study analyzes scientific approaches to enriching whey with mineral elements through spark discharge treatment, which creates optimal conditions for cultivating lactic acid bacteria. The primary aim of the study is to examine the fermentation process of whey enriched with mineral elements and its impact on the rheological properties of dough and the quality of finished bakery products. It has been established that spark discharge treatment of whey significantly accelerates the fermentation process, increases acidity, and boosts the growth of lactic acid bacteria. The research shows that using enriched whey allows the fermentation time to be reduced by almost half compared to the control. This is achieved through intensive acid production and biomass growth of lactic acid bacteria. The best results were obtained with whey treated with spark discharges in a conductive layer of zinc, magnesium, and manganese granules. Using fermented whey in the production of ryewheat bread contributed to increasing the gas-forming capacity of the dough, improving its rheological properties, and increasing the specific volume of finished products. Enriched whey also positively affected the bread's quality by enhancing its porosity, shape stability, and organoleptic properties. It was found that enriching whey with magnesium, zinc, and manganese not only intensifies the fermentation process but also increases the nutritional value of the finished products by enriching them with important microelements. The study demonstrated that using enriched whey reduces dough ball spread, increases its elasticity and resilience, and extends the bread's freshness. The research results confirm the feasibility of using spark discharge enrichment of whey with magnesium, zinc, and manganese to improve the efficiency and quality of bakery production. The proposed technology can be recommended for widespread implementation in production, ensuring high quality and competitiveness of bakery products in the market.
Diagnóstico de los procesos de inclusión en las escuelas normales desde el enfoque de la socioformación
Authors: Mounkoro Ismaila
Published: June 2024

El estudio busco diagnosticar los procesos de inclusión en escuelas normales desde el enfoque de la socioformación, identificando fortalezas, oportunidades, debilidades y amenazas. Se realizó un análisis cuantitativo con 247 participantes de México, Mali y Francia, utilizando una rúbrica socioformativa y un cuestionario de 6 preguntas. Los resultados indican que muchos encuestados consideran satisfactorias las prácticas inclusivas actuales, mostrando un enfoque proactivo y autodirigido. Sin embargo, se necesita mejorar y expandir estas prácticas para una inclusión más efectiva. El estudio resalta la importancia de fortalecer la formación docente, diseñar estrategias personalizadas y promover la socioformación como enfoque pedagógico clave. Concluye que, aunque hay avances significativos, persisten desafíos para alcanzar una inclusión plena, y se requiere un compromiso institucional continuo para lograr una educación verdaderamente inclusiva.
Potential of endovideosurgery in the treatment of children with focal pancreatic lesions
Authors: Efremenkov A. M. , Sokolov Yu. Yu. , Akhmatov R. A. , Akopyan M. K. , Vilesov А. V. , Zykin A. P.
Published: June 2024

Aim. To evaluate the effectiveness of laparoscopic surgeries for diseases and malformations of the pancreas in children.

   Materials and methods. 53 laparoscopies were performed from 2005 to 2023. Enucleation was performed in 16 children, distal resection of the pancreas with spleen preservation – in 16, corpo-caudal resection of the pancreas – in 4, subtotal resection of the pancreas – in 9, central resection of the pancreas – in 5, head resection with duodenal preservation – in 1, pancreaticoduodenal resection with pyloric preservation – in 2 children. The age of the children ranged from 2 months to 17 years.

   Results. All surgeries have achieved the intended clinical effect. The average time of enucleation accounted for 88.1 ± 47.7 min., distal resection with spleen preservation – 100.3 ± 21 min., corpo-caudal resection – 113.3 ± 28.9min., subtotal resection – 101 ± 21.7 min., central resection – 243.3 ± 81.1 min., head resection with duodenal preservation – 235 min., pancreaticoduodenal resection with pyloric preservation – laparoscopic and laparoscopically assisted – 435 and 415 min. Intraoperative bleeding was noted in 6 cases (11.3 %), in 2 (3.8 %) conversion was performed in 2 cases (3.8 %). The postoperative period revealed 6 (13.2 %) early and 8 (15.1 %) late complications. No fatal outcomes reported. The follow-up ranged from 1 to 10 years, no recurrences reported.

   Conclusion. Focal pancreatic lesions in children refer to heterogeneous diseases and malformations requiring various resection interventions. Laparoscopic enucleation and distal resection of the pancreas are considered as the most effective. Further clinical experience is required to explore the feasibility of using laparoscopy in children to perform central resection of the pancreas and pancreaticoduodenectomy.
New method for surgical treatment of pancreatic head cysts
Authors: Savin D. V. , Demin D. B. , Zheleznov L. M.
Published: June 2024

Aim. To evaluate the clinical efficacy of a new method for drainage of pancreatic head cysts.

   Materials and methods. The results of treatment of 3 patients with pancreatic head cysts were analyzed in a new way. In all patients, cysts developed against the background of recurrent pancreatitis; the etiology of pancreatitis was alimentary. All cysts were located in the pancreatic head, mainly on its posterior surface, communicating with the ductal system.

   Results. No intra- and postoperative complications were revealed. Patients were discharged from hospital on the 8–12th day after surgery. In all observations, good results were obtained: no pain syndrome reported; psychological status and food intake normalized. α-amylase in urine and plasma has not increased. No recurrence of cysts and no hospitalizations for acute pancreatitis were reported.

   Conclusion. The developed method for treating pancreatic head cysts communicating with the ductal system proved to be physiological, low-traumatic and can be used in surgical practice.
Aprendizaje experiencial: fortaleciendo competencias clave para el liderazgo empresarial integral
Authors: López Calvo Karen María
Published: June 2024

Hoy el contexto empresarial, marcado por la creciente complejidad y la volatilidad de los entornos y por la incertidumbre y la ambigüedad que caracterizan numerosos aspectos de la realidad económica, social, política, medioambiental y tecnológica, presenta un desafío constante para las organizaciones empresariales y sus líderes en aras de hacer frente a la multiplicidad de factores que influyen en el desenvolvimiento de las organizaciones. En este sentido la exigencia de una formación integral se erige como pilar fundamental para el desarrollo personal y profesional de los líderes empresariales, quienes deben adaptarse y evolucionar constantemente para enfrentar los retos emergentes y conducir a sus organizaciones hacia la competitividad y la sostenibilidad en un entorno dinámico y exigente.
Investment strategies based on investors’ mood: Better for crypto
Authors: Gómez Martínez Raúl , Medrano García María Luisa , Veiga Mateos Jaime
Published: June 2024

Objective.Analyze the utility of an algorithmic trading system based on artificial intelligence models that uses Google Trends as predictor of dozens of financial terms, to predict the evolution of S&P 500 index and Bitcoin. Methodology. A trading algorithmic system has been developed that opens a weekly long or short position in S&P 500 and Bitcoin, following the signals issued by an artificial intelligence model that uses Google Tends as predictor for next week market trend. The artificial intelligence models were trained using weekly data from 2013 to 2018 and have been tested in a prospective way from February 2018 to December 2021. Results. Google Trends is a good predictor for global investors’ mood. The artificial intelligence algorithmic trading systems tested in a prospective way has been profitable. Trading strategies based on investors’ mood have been more accurate and profitable for Bitcoin (beating the evolution of the cryptocurrency) than for S&P 500 (not beating the index). Conclusions. This evidence opens a new field for the investigation of trading systems based on big data instead of Chartism. Although there are many trading systems based on Chartism, there are no artificial intelligence trading syste
The Development of Environmental Friendly Biological Sulfur Recovery Unit (BSRU) For Sulfur Coated Urea with Slow Release Fertilizer Method: A Case Study in Field X
Authors: Indriani Erdila , Athallah Fairuz , Despriadi Eryko , Purnomosidi Purnomosidi
Published: June 2024

The absorption of nitrogen from urea fertilizer is significantly inefficient. Due to its solubility in water. This problem can be overcome by producing slow-release fertilizer (SRF) that inhibits urea from being dissolved in water. Sulfur-coated urea (SCU) is one of the SRF methods. Therefore, this study aimed sulfur-coated slow-release urea fertilizer using sulfur waste from the Biological Sulfur Recovery Unit (BSRU) in Field X. A total of 14 tons of sulfur cake was produced daily by BSRU in Field X and sent to the laboratory for composition analysis, followed by drying. Subsequently, the dried sulfur was into a powder using a hammer and sieved to achieve a size of 200 mesh. Based on the results, SCU with the sulfur to urea ratio of 1:1 and mixing time of 15 minutes exhibited the best performance in dissolution tests with the longest dissolution time of 5 minutes which was better compared to the uncoated urea. After 7 days of observation, spinach that received SCU was more fertile and greener. The calculated NPV and payout time were 88712 million   IDR and 1.76 years, respectively. This indicated that the development of this study was economically attractive. In conclusion, the value of sulfur waste from gas processing was increased by using sulfur waste from BSRU as a coating of urea while reducing related environmental effects.
Predictive Model for the classification of university students at risk of academic loss
Authors: Gamboa Mora María Cristina , Vivián Mohr Felix , Ahumada De La Rosa Vicky , Vera-Monroy Sulma Paola , Mejía-Camacho Alexander
Published: June 2024

For higher education institutions, predicting the risk of academic loss is a priority issue due to the resources invested by institutions, students and the academic community in general. Objective: the objective of this research was to propose a suitable model that allows predicting students who are at risk of academic loss in a chemistry course. Methodology: the quasi-experimental, predictive, longitudinal research was developed with data from 103 students from four Colombian universities. To build the model, a comparison of five algorithms was implemented. Data was processed with Jupyter-Python. Results: the logistic regression model (LR) was built based on the students’ results on the Saber 11 test (Colombian nation-wide university admission exam), in which the penalty of false positives with different weights from the false negatives improved the performance of the model. Conclusions: it is concluded that LR is substantially better than grasping or a guessing approach, furthermore, it was shown to perform better than a neural network model.
Lifestyle Eco-Influencers Advertising: Is Engagement Driven by Content or Fandom?
Authors: Castillo-Abdul Bárbara , Romero-Rodríguez Luis Miguel , Fernández-Rodríguez Carlos
Published: June 2024

This research examines the main common characteristics among the contents of five eco-influencer accounts from different Western countries. A quantitative content analysis was performed on 187 Instagram posts published by eco-influencers from the United Kingdom, United States, Belgium, Spain, and Peru. The topics that eco-influencers deal with the most are promoting veganism, spirituality, environmental and political claims, product advertising (their own and third-party), and personal life, generating the most interactions in the accounts. Carousels win on engagement for eco-influencers on Instagram despite videos being sponsors’ favorite format. Both sponsored content and sponsors themselves are well-received, with over half of all posts featuring them. It seems evident that the social capital of influencers encourages environmental commitment, although there is a particular bias to appreciate the person more than their activist message. In light of the results, this research contributes to the social capital theory of influencers by demonstrating that influencers show personal content and emotional appeals, such as activities with their families, personal reflections, and political statements that give them a high sense of authenticity, but which, blurs the barriers between the public and private spheres.
IF Labeling Protocol v1
Authors: Vermilyea Scott
Published: June 2024

This protocol details the Labelling of Immunofluorescent Protein.
Maintenance & Differentiation: Embryonic Mouse Hippocampal Cells (CLU198) v1
Authors: Razaul Karim Md
Published: June 2024

This protocol details the maintenance & differentiation of Embryonic Mouse Hippocampal Cells (CLU198).
Lysosomal Membrane Permeability (LMP) assay v1
Authors: Vermilyea Scott
Published: June 2024

This protocol details the requirements of the Lysosomal Membrane Permeability (LMP) assay.
LYSOSOMAL ISOLATION PROTOCOL v1
Authors: Vermilyea Scott
Published: June 2024

This protocol details the isolation of lysosomes.
Decreased Memory-related Regional Cerebral Perfusion in Severe Obstructive Sleep Apnoea With a Mild Cognitive Impairment v1
Authors: Xiangbo Yan
Published: June 2024

We will use arterial spin labeling (ASL) technology to quantify and evaluate abnormal changes in resting state cerebral blood perfusion in patients with obstructive sleep apnea (OSA) with cognitive impairment (CI) and to explore the underlying neuropathological mechanisms in patients with OSA and CI (OSA-CI). The findings are basically in line with our study hypothesis.OSA-CI patients, similar to AD and MCI, may initially present with decreased memory function. The progressive aggravation of hemodynamic abnormalities in the bilateral inferior temporal gyrus and left lingual gyrusin OSA patients may contribute to decreased brain memory function and subsequent memory dysfunction.
Actitudes lingüísticas hacia el mapudungun: estudio exploratorio en jóvenes de la Araucanía y Biobío
Authors:   Universidad Católica de la Santísima Concepción, Becerra Soto Carol , Henríquez Barahona Marisol ,   Universidad Católica de la Santísima Concepción
Published: June 2024

Este artículo se enmarca en el ámbito de las actitudes lingüísticas en contextos de contacto y desplazamiento lingüístico. El abordaje de los sistemas de creencias y valoraciones subjetivas de los hablantes de lenguas minorizadas es relevante, pues evidencia y proyecta las motivaciones que subyacen al comportamiento sociolingüístico de las comunidades y provee aportes para el diseño e implementación de programas de enseñanza y revitalización lingüística. En esta propuesta se examinan las principales actitudes lingüísticas de jóvenes mapuches hacia el mapudungun y su proceso de revitalización. El enfoque es cualitativo y los datos se obtuvieron a través de entrevistas semiestructuradas que se realizaron a colaboradores mapuches bilingües pertenecientes a diferentes comunidades de Araucanía y Biobío en Chile. Los resultados muestran actitudes muy positivas en torno a la lengua originaria y un conflicto actitudinal que podría influir en la decisión de no querer hablar mapudungun. En cuanto a la revitalización lingüística, los jóvenes identificaron diferentes agentes responsables de este proceso, donde la escuela podría cumplir un rol fundamental si se realizan transformaciones estructurales.
Barriers and strategies for scaling up livestock agroforestry systems in the amazon piedmont, Caquetá - Colombia
Authors:   The Nature Conservancy – Sustainable Production Systems Program, Solarte Antonio , Rico Adrián ,   Centro para la Investigación en Sistemas Sostenibles de Producción Agropecuaria – CIPAV, Zapata Catalina , Chará Julián ,   Centro para la Investigación en Sistemas Sostenibles de Producción Agropecuaria – CIPAV, Murgueitio Enrique ,   Centro para la Investigación en Sistemas Sostenibles de Producción Agropecuaria – CIPAV
Published: June 2024

Background: Silvopastoral systems (SPS) are an option for sustainable livestock production, but although their multiple benefits have been demonstrated, its adoption has been limited. Objective: To identify the barriers to the adoption of SPS, according to the perceptions of producers and the strategies to promote adoption as a tool for sustainable cattle ranching in the Amazonian foothills of the Caquetá province. Methods: Experts on sustainable cattle ranching from public and private organizations implementing projects in the province of Caquetá in this topic were called to contribute in participatory rural appraisal workshops and focus groups. These workshops had also the participation of producers from the municipalities of the south of the province with 3 to 5 years of experience in the establishment of SPS, and producers from the north of the province who were just starting with SPS. Results: The experts recognized 13 practices or alternatives promoted by institutions for sustainable cattle ranching. These alternatives were categorized into pasture management, livestock agroforestry, conservation, and renewable energy. They also identified 21 barriers that limit the adoption of these alternatives, which were grouped into skills and knowledge, social, economic, environmental, and technical and operational barriers. The cattle ranchers’ farmers prioritized and established the advantages and disadvantages of the four main SPS. In response to the barriers to adoption, 22 scaling-up strategies were identified and classified into five categories which contribute to promote adoption of SPS. Conclusions: Organizations that promote sustainable practices for sustainable cattle ranching in the Caquetá foothills and farmers recognize the importance of SPS, but there are still barriers related to knowledge, implementation costs, environmental and cultural conditions that need to be addressed to increase adoption.
Yapılandırmacı Öğretim Programına Uygun Olarak Hazırlanmış Çalışma Yapraklarıyla Üçgenler Konusunun 8’inci Sınıflara Öğretimi
Authors: Keskin Seda , Işık Ahmet
Published: June 2024

Bu çalışmanın amacı, yapılandırmacı öğretim programına uygun olarak hazırlanmış çalışma yapraklarıyla geometri öğrenme alanında yer alan üçgenler konusunun 8’inci sınıflara öğretiminin incelenmesidir. Araştırmada, nicel veri toplama yöntemlerinden yarı deneysel desen tercih edilmiştir. Araştırma, Ankara İli Etimesgut ilçesinde bulunan bir devlet ortaokulunun 8’inci sınıf öğrencileriyle yapılmıştır. Araştırmanın çalışma grubu 58 öğrenciden (28 kontrol grubu ve 30 deney grubu) oluşmaktadır. Araştırmada öğrencilere üçgenler konusu öğretilirken deney grubuna yapılandırmacı öğretim programına uygun olarak hazırlanmış, çalışma yapraklarıyla öğretim yapılmış ve kontrol grubuna ise genel öğretim yöntemleri ile öğretim yapılmıştır. Öğrencilerin başarıları ise araştırmacı tarafından geliştirilen “Üçgenler Başarı Testi” ile analiz edilmiştir. Sonuçta, 8’inci sınıf öğrencilerinin akademik başarılarının deney grubu lehine farklılaştığı görülmüştür. Bu sonuca göre öğrencilerin üçgenler konusundaki başarılarının artmasında, yapılandırmacı öğretim yöntemine uygun olarak hazırlanmış çalışma yapraklarıyla öğretimin genel öğretimden daha etkili olduğu söylenebilir.
Estudio De Caso Del Impacto Del Proyecto Comunidades De Aprendizaje En El Aumento De La Empleabilidad De La Población Gitana En Situación De Desigualdad Social
Authors: Grau Del Valle Carolina , García-Raga Laura , Barrachina-Sauri Mireia , Roca-Campos Esther
Published: June 2024

Existe literatura científica que muestra el impacto del proyecto educativo de ‘Comunidades de Aprendizaje’ (CdA) en el desarrollo de competencias sociopersonales y en una mejor y mayor trayectoria académica en colectivos vulnerables pertenecientes al pueblo gitano. Un amplio campo de la literatura señala la correlación de estos factores con el aumento de la empleabilidad.  Sin embargo, existe poca investigación que analice los resultados de las CdA en el aumento de la empleabilidad de las personas gitanas participantes. Esta investigación, a través de un estudio de caso único, identifica el impacto de una CdA, donde el 88% de sus miembros pertenece al colectivo gitano en situación de desigualdad social, en el aumento de su empleabilidad. Para llevar a cabo este análisis se utilizó una metodología de enfoque comunicativo. Las técnicas de investigación aplicadas fueron 6 relatos comunicativos a 3 mujeres y 3 hombres pertenecientes a comunidad gitana en riesgo de exclusión y 2 grupos de discusión dialógica a 5 profesionales de la escuela. Tomando como referencia indicadores de empleabilidad recogidos en la literatura científica, los datos muestran en qué medida el proyecto está mejorando la empleabilidad en estas 6 personas gitanas y qué actuaciones tienen mayor incidencia en dicho impacto.
Diagnostic Efficacy of Trephine Biopsy and Core Biopsy of Bone and Soft Tissue Tumors
Authors: Saprykina E. A. , Teplyakov V. V. , Shaposhnikov A. A. , Lazukin A. V. , Ukhvarkin A. P. , Dobrosotsky S. V.
Published: June 2024

Verification of pathomorphological diagnosis is a key stage in selection of treatment tactics in patients with neoplasms. Understanding of the nature of pathological process is especially important in context of primary tumors of the bones, soft tissues and metastases as despite active development of diagnostic techniques, they do not allow to obtain full information on histological nature of the tissues, differentiation grade, as well as molecular and genetic characteristics of the tumor. These data are associated with selection of optimal treatment tactics at every stage and disease prognosis. The optimal approach to obtaining histological materials in tumor of the bones and soft tissues are radiologically guided (X-ray, computed tomography and magnetic resonance imaging) trephine biopsy or ultra-sound-guided core biopsy.

Aim. To determine information value of trephine and core biopsies of neoplasms of the bones and soft tissues of various locations, identify mistakes during manipulation affecting results of morphological diagnosis.

Materials and methods. Between 2015 and 2023 at the Russian Scientific Center of Roentgenoradiology, 788 patients aged 18–85 years (380 men, 408 women) underwent 602 trephine biopsies and 248 core biopsies (n = 850) of neo-plasms of the soft tissues and bones of various locations. Absence of informational value of morphological study required repeat trephine biopsies in 19 patients, core biopsies in 2 patients, open biopsies in 13 patients.

Results. Informational value of trephine biopsy of the bones was 90.5 % (long bones – 96.8 %, flat bones – 91.6 %, spine bones – 82.1 %), core biopsy of the soft tissues 98.8 %. Sufficient amount of material for immunohistochemical testing was obtained in 89 % biopsies. Interventions in cases of bone neoplasms were performed using CT (computed tomography) navigation; for core biopsies of the soft tissues, ultrasound was used. Absence of informational value in trephine bio psies was caused by insufficient amount of material (48 (7.97 %) cases), retrieval of trephine biopsy from the area of tumor necrosis (4 (0.67 %) cases), incorrect selection of access (4 (0.67 %) cases) and needle type (1 (0.17 %) case).

Conclusion. Results of analysis of trephine and core biopsy data of bone and soft tissue neoplasms showed high information value, which is supported by literature data. This allows to consider these methods of histological material retrieval the “golden standard” of bone and soft tissue tumor diagnosis.
Determination of synergic antioxidant interactions of Ellagic acid, cemotherapy drugs (Docetaxel and Mitoxantron) and their combinations
Authors: Zehiroğlu Cuma , Ö. Sarıkaya S. Beyza
Published: June 2024

Chemotherapy drugs are commonly used in cancer treatment, despite their numerous negative side effects. Today, there are studies to reduce the side effects of these drugs and to increase their benefits by combining them with natural substances. Our study investigated the antioxidant and antiradical activities of Ellagic acid (EA), a natural substance, DOC and MIX, commonly used chemotherapeutics, as well as their combinations (EA+DOC, EA+MIX). For this purpose, the methods of DPPH• and ABTS•+ scavenging activity, Fe3+-Fe2+ and Cu2+-Cu1+ reduction capacity were used. After the study, the interactions were analysed with the combination index using Compusyn software. Concentrations with maximum synergy in combinations have been identified. For this purpose, firstly, the combination concentrations used in the antioxidant activity methods and the absorbance values were entered into the Compusyn programme. When DPPH• and ABTS•+ scavenging activity results were entered into the programme, more effective synergistic effect was observed for EA+DOC at lower concentrations (7:7µg/mL), (0.125:1µg/mL) respectively. For EA+MIX, no synergistic effect was observed with the application of DPPH scavenging activity results to the programme, while for ABTS•+ scavenging activity, more effective synergistic effect was observed at higher concentrations within the applied doses (0.750:6µg/ml). When Fe3+-Fe2+ and Cu2+-Cu1+ reduction results were applied to the programme; synergistic effect was observed at higher concentrations (17:17µg/mL) for both EA+DOC and EA+MIX and even strong synergistic effect was observed in many of them. The obtained results provide guidance for the use of these combinations in further studies, such as anticancer and enzyme studies.
Intercultural approach to studying English for Japanese studies students: a textbook review
Authors:   Taras Shevchenko National University of Kyiv, Kyiv, Ukraine, Druzhchenko Tetiana , Semyan Nataliya ,   Taras Shevchenko National University of Kyiv, Kyiv, Ukraine
Published: June 2024

This publication is a review of the textbook by Nataliia Semian and Tetiana Druzhchenko, "Exploring Cultural Contrasts: Japan and Ukraine in English Classes" (2024). This textbook was developed for teaching English at the university level using comparative strategies as part of the foreign language curriculum for second- and third-year undergraduate students majoring in Japanese studies. Grounded in an intercultural approach, interdisciplinary connections, and a cognitive-communicative concept of foreign language acquisition, the authors encourage students to explore and analyze cultural contrasts and similarities between Japan and Ukraine. The textbook is designed to provide students with specialized knowledge for practical use in professional English for students of Eastern studies, satisfy their intellectual and cultural needs, and promote the development of their professional competencies. The textbook employs contrast and comparison strategies aimed at developing monologic and dialogic English skills, which can be used in discussions about similar and different cultural objects, daily life, literature, art, and the histories of Ukraine and Japan. By exploring linguistic features and cultural realities, students can enhance their language skills and gain a deeper understanding of the cultural context of communication. Thus, the intercultural approach is not only a tool for scholarly research but also a comprehensive and systematic method of teaching English. It helps students appreciate cultural diversity and ensures their success in their professional and academic growth.
Investigation of Phenolic, Flavonoid and Total Antioxidant Capacity of Sumac (Rhus Coriaria L.) Plant Grown in Different Regions and Subjected to Different Preservation Methods
Authors: Ali Muhammad Haval , Çakmak Meltem , Karataş Fikret , Özer Dursun , Saydam Sinan
Published: June 2024

The total amount of phenolic and flavonoid compounds and the total antioxidant capacity of sumac samples grown in different regions were determined by spectrophotometer. Freshly ground samples were divided into three parts, first part analyzed immediately, second one oiled and third one kept as it is for six months. The total phenolic and flavonoid compounds were found in between 27.73-51.75 µg GAE (g dw)-1 and 16.16 -33.50 µg QE (g dw)-1, respectively for fresh samples. The samples that were grounded and kept for six months, the same parameters were observed to be 19.31 - 37.75 µg GAE (g dw)-1 and 10.76 -21.82 µg QE (g dw)-1, respectively.
IC50 and TEAC values in freshly ground sumac samples were found between 14.79-23.80 µg mL-1 and 359.30-665.62 µmol trolox (g dw)-1, respectively. IC50 and TEAC values in the samples oiled were determined to be in between 17.51 - 27.70 µg mL-1 and 306.69 - 517.40 µmol trolox (g dw)-1, respectively.
From these findings, it can be said that higher the amount of total phenolic and flavonoid compounds in the samples better the total antioxidant capacity. The decreases in the examined parameters of the samples with oil are lower than those kept without oiling (p>0.05). The differences in the examined parameters can be explained by the difference in geographical and ecological conditions.
Surgical treatment of secondary refractory glaucoma in chronic uveitis with corneal dystrophy (clinical case)
Authors: Starostina Anna V. , Uyanaeva Aila A. , Adzhieva Amina A. , Taevere Mariam R. , Khabazova Margarita R.
Published: June 2024

BACKGROUND: Uveitis is the inflammation of the iris, ciliary body, vitreous, retina, or vascular membrane, in which the most common complication is a secondary increase in intraocular pressure that is difficult to compensate with antihypertensive drugs. Ahmed valve implantation in uveal glaucoma is an effective surgical method to reduce intraocular pressure.
CLINICAL CASE DESCRIPTION: In the Department of Surgical Treatment of Glaucoma of the S. Fyodorov Eye Microsurgery Federal State Institution, Ahmed valve implantation was performed in two patients with refractory, repeatedly operated uveal glaucoma. As a result of valve implantation, in both cases, compensation of intraocular pressure within up to 15 months after surgery was possible.
CONCLUSION: Ahmed valve implantation in secondary uveal repeatedly operated glaucoma in patients with chronic uveitis and corneal dystrophy achieved compensation of intraocular pressure and preserved visual functions.
Unilateral pulmonary vein atresia: Difficulties of radiological diagnosis
Authors: Zharikova Veronika V. , Nechaev Valentin A. , Kulikova Evgenia A. , Yudin Andrey L.
Published: June 2024

Pulmonary vein atresia is a rare congenital abnormality that could manifest in isolation or in association with other congenital abnormalities in the cardiovascular system such as pulmonary vein hypoplasia. Pulmonary vein atresia leads to changes in cardiovascular functioning. This abnormality is often diagnosed in children with recurrent pneumonia and hemoptysis. In adulthood, pulmonary vein atresia is much less common, with clinical symptoms such as dyspnea during physical exercises and hemoptysis. However, some patients are asymptomatic. Owing to the nonspecific imaging findings, lung parenchymal changes are often misdiagnosed as another lung disease, including inflammatory genesis disease. In this article, a case of a young man with asymptomatic unilateral pulmonary vein atresia combined with pulmonary artery hypoplasia and interstitial lung changes in a lung with hypoplasia was presented. These pathologies were first identified in a 21-year-old patient by contrast-enhanced computed tomography.
The Pragmatic Functions of High-Frequency Discourse Marker So in Chinese EFL Teacher Talk
Authors: Wei Kexin , Li Siqing
Published: June 2024

Discourse markers have multiple pragmatic functions and have significant influences on classroom organization and teaching. This study aims to analyze the pragmatic functions of discourse marker so in a self-built corpus of Chinese middle school English classroom discourse. The corpus analysis shows that discourse marker so has various pragmatic functions, including marking results and inferences, managing topics, summarizing, rewording and giving examples at the textual level. Besides, at the interactional level, so functions as a marker of speech acts such as questions, requests, opinions, elicitations and confirmations. The research shows that discourse marker so can make classroom discourse more closely linked, promote students’ understanding of teacher’s discourse and create a harmonious classroom atmosphere. The findings of this research might have important implications for English teaching and teachers’ professional development in middle schools.
The flow of information in the creation of a microlearning on circular economyFelipe Lopes Roberto
Authors: Lopes Roberto Felipe , Do Carmo Duarte Freitas Maria , Hélio Junqueira Antonio
Published: June 2024

Introduction: The area of education is important for a Circular Economy, as the transition to circular models requires individuals and organizations that learn to innovate and put into practice what they have learned in the real world. This area, from elementary school to graduate school, plays a vital role in ensuring that students of all ages are equipped with the key skills and knowledge to execute circular thinking in their careers. Objective: Map the information flow stages present in the MOOC production process on Circular Economy. Methodology: This research is characterized as exploratory in terms of its objectives and analyzes the flow of information in the process of creating an informational product with regard to procedures. Results: This research showed that an activity of an interdisciplinary nature, such as Information Management - which evolves over time, mainly due to technological innovations - contributed to mapping the stages of needs, obtaining, treatment, distribution, use, storage and disposal of information from the information flow within the process of developing an information product – in this case, the IEC MOOC. Conclusion: Associated with the concepts of information architecture, information design and information ergonomics, GI helped in the structuring, organization and presentation of educational information, optimizing the transmission of knowledge and user experience.
Executive Summary: Framework to Support Populations in Situations of Fragility, Conflict and Criminal Violence: 2024-2027
Authors: Schijman Agustina , Alvarado Nathalie , Sipp Caroline , Abuelafia Emmanuel , Mejía Juan Andrés , Giles Álvarez Laura , Gutiérrez Juárez Priscilla , Peña Norma , Villa-Mar Karelia , Perez-Vincent Santiago M. , Tachlian-Degras Edwin , Escala Mendez Victor Hugo , Acevedo María Cecilia , Soares Yuri
Published: June 2024

Fragility, conflict, and criminal violence (FCCV) undermine the quality of life and livelihoods of millions of people in Latin America and the Caribbean. Each new shock and crisis in these settings reinforces underlying fragilities and creates ripple effects that usually span across borders and can affect development prospects of other regions. Addressing, preventing, and mitigating these situations is a global public good, critical to countries in Latin America and the Caribbean, their populations, and to the main mandate of the Inter-American Development Bank Group (IDB Group) to improve lives in the region. While the IDB has extensive experience and comparative advantages tackling FCCV-related issues, we have so far lacked a unified approach to the topic as a Group. This new framework provides clear guidance on adapting our work to FCCV settings and aims to deliver tangible impacts through both financial and non-financial initiatives.
Los peces desérticos del bajo río Pisco, costa del Pacífico, Ica, Perú
Authors: Apaza José , Aylas Katia , Chumbe-Nolasco Lenin D. , Valenzuela Silvia , Raunelli Giulia , Amézquita-Bejar Lucero Stephany , Espinoza-Rojas Yuli Dulcina , Ortega Hernán
Published: June 2024

Este estudio aborda la fauna íctica registrada en el bajo río Pisco en Ica, costa central de Perú. Se examinaron los especímenes depositados en la Colección Ictiológica MUSM, que incluye evaluaciones de campo realizadas en el cauce principal del río Pisco, humedal Pisco Playa, laguna Morón y poza Lagunillas, así como estudios hallados en la literatura disponible. Se documentaron 13 especies de peces pertenecientes a ocho familias y ocho órdenes, siendo la familia Cichlidae la de mayor diversidad, con cuatro especies. Lebiasina bimaculata representa un nuevo registro de la ictiofauna del río Pisco. La riqueza de especies varió según el ambiente evaluado, siendo el humedal Pisco Playa y el río Pisco los ambientes con mayor diversidad, al albergar nueve y ocho especies, respectivamente. En cuanto a la composición de las especies, Andinoacara stalsbergi, Poecilia reticulata y Oreochromis sp. se encontraron en los cuatro ambientes acuáticos evaluados y se las podría considerar como especies núcleo, mientras que Basilichthys semotilus se registró únicamente en el río Pisco. En términos de tolerancia a la salinidad, se identificaron una especie primaria, 11 secundarias y una periférica. Según su origen, las especies exóticas representan el 53,8 % de la riqueza total, destacándose Oreochromis sp. y P. reticulata por estar presentes en todos los ambientes evaluados. Nuestro estudio contribuye en la actualización del conocimiento de la riqueza íctica en el bajo río Pisco y proporciona una herramienta valiosa para la gestión, divulgación y conservación de la biota acuática en esta región.
Maíces con alto contenido de antocianina, biofortificados con zinc, provitamina A y de alta calidad de proteína en Perú
Authors: Narro León Luis A. , Chávez Cabrera Alexander , Piña Díaz Peter C. , Escobal Valencia Fernando , Medina Hoyos Alicia E. , Narro León Teodoro P. , Alvarado Rodríguez Roberto , Vargas Gutiérrez Kryss A. , Velásquez Leveaú Fabian C. , Escalante Vega Mercedes , García Pando Gilberto A. , Carrillo Zavala Pedro , Rengifo Sánchez Raihil , Ricse Belen Elizabeth , Flores Mendoza Demetrio , Huamanchay Rodriguez Willian M. , Otiniano Villanueva Ronal
Published: June 2024

Más de 2000 millones de personas en el mundo padecen “hambre oculta” por insuficiencia de minerales y/o vitaminas en la dieta diaria. La situación del hambre en Perú pasó de 17.7 a 19.6 puntos de 2021 a 2022. La biofortificación de cultivos surgió como una iniciativa para ayudar a solucionar este problema mediante la producción de plantas con mayor contenido de zinc (Zn), hierro (Fe) y provitamina A (ProA) en el grano utilizando métodos de mejoramiento convencional (no transgénicos). Los resultados obtenidos en el Perú nos muestran que existen híbridos de maíz biofortificado, con alto contenido de Zn y ProA, y con muy buen potencial de rendimiento. Para el caso del maíz morado, con alto contenido de antocianinas, un fitoquímico que tiene efectos beneficiosos para la salud de las personas, se está estudiando la adaptación de las variedades en todo el país tanto para el rendimiento del grano como para el contenido de antocianinas. Resultados preliminares indican que hay claras diferencias entre variedades para rendimiento y contenido de antocianina en la coronta, brácteas y grano. La producción de maíz morado se ha cuadruplicado en los últimos 20 años por un mayor consumo interno y por el incremento en las exportaciones. Sin embargo, su contribución al Producto Bruto Interno (PBI) es muy baja: menor al 1 %; lo que es un reto y una oportunidad para desarrollar y transferir tecnología que incremente la producción y vincule al productor de maíz morado con el consumidor. En el caso de maíz de alta calidad de proteína (QPM), se ha liberado en el Perú un híbrido simple (QPM) de color amarillo intenso, con alto potencial de rendimiento y amplia adaptación.
Norwid’s drama of “social transfigurations”
Authors: Ziołowicz Agnieszka
Published: June 2024

The article discusses Norwid’s concept of drama and theatre; notably, he assumes their close relationship with social life and its historical changes. Basing on analyses of meta-dramatic and meta-theatrical statements made by the poet, contained primarily in the essays “Widowiska w ogóle uważane” and “Białe kwiaty” [Performances considered in general; White flowers], in passages from lectures on Słowacki (O Juliuszu Słowackim), and in the introduction to Pierścień Wielkiej-Damy [The Ring of a Great Lady], it is possible to formulate the thesis that Norwid intentionally developed a vision of drama based on the idea of “social transfigurations.”What is more, the character of his dramatic works enables one to interpret his particular theatrical pieces in the light of anthropological and sociological categories of social drama and cultural performance. After all, most of Norwid’s dramatic works depict situations of social change in terms of rites of passage and theatricalized social practices, e.g. social ceremonies or ritualized interactions. As a result, Norwidian drama becomes an artistic representation of forces shaping collective life, a lens facilitating their understanding in the spirit of social anthropology, and an important factor in the formation of man.