bluuebunny/crossref_metadata_2025 huggingface dataset:
Two‐Directional Elaboration of Hydroxyacetone under Thermodynamically Controlled Conditions: Allylation or 2‐Propynylation and Aldol Reaction.
Authors: Ishikawa Teruhiko , Aikawa Toshiaki , Ohata Eiko , Iseki Takako , Maeda Satoshi , Matsuo Takashi , Fujino Tatsuo , Saito Seiki
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Facile Synthesis of Phenacyl Iodides from Styrenes under Visible Light Irradiation with Fluorescent Lamps.
Authors: Nakayama Hiroki , Itoh Akichika
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
An Easy Route to Atropoisomeric Bipyridine N,N′‐Dioxides and Allylation of Aldehydes.
Authors: Hrdina Radim , Kadlcikova Aneta , Valterova Irena , Hodacova Jana , Kotora Martin
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Hydrosilylation of Ketones Catalyzed by C2‐Symmetric Proline‐Derived Complexes.
Authors: Gan Li , Brook Michael A.
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Multipolymer Reaction System for Selective Aerobic Alcohol Oxidation: Simultaneous Use of Multiple Different Polymer‐Supported Ligands.
Authors: Chung Cecilia Wan Ying , Toy Patrick H.
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Novel Synthetic Methodologies. Part 82. Synthetic Applications of Baylis—Hillman Chemistry: An Efficient and Solely Stereoselective Synthesis of (E)‐α‐Methylcinnamic Acids and Potent Hypolipidemic Agent LK‐903 from Unmodified Baylis—Hillman Adducts.
Authors: Das Biswanath , Banerjee Joydeep , Chowdhury Nikhil , Majhi Anjoy
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of 6‐(Perfluoroalkyl)salicylates by [3 + 3] Cyclization of 1,3‐Bis(silyl enol ethers) with 3‐Ethoxy‐1‐(perfluoroalkyl)prop‐2‐en‐1‐ones.
Authors: Lubbe Mathias , Mamat Constantin , Fischer Christine , Langer Peter
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
o‐Iodoxybenzoic Acid‐ and Tetraethylammonium Bromide‐Mediated Oxidative Transformation of Primary Carboxamides to One‐Carbon Dehomologated Nitriles.
Authors: Bhalerao Dinesh S. , Mahajan Ulhas S. , Chaudhari Kiran H. , Akamanchi Krishnacharya G.
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Ni‐Catalyzed Activation of α‐Chloroesters: A Simple Method for the Synthesis of α‐Arylesters and β‐Hydroxyesters.
Authors: Durandetti Muriel , Gosmini Corinne , Perichon Jacques
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A Simple Route to 6‐ and 7‐Fluoro‐Substituted Naphthalene‐1‐carboxylic Acids.
Authors: Kruelle Thomas M. , Barba Oscar , Davis Susan H. , Dawson Graham , Procter Martin J. , Staroske Thomas , Thomas Gerard H.
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Lewis‐Acid‐Catalyzed Rearrangement of Arylvinylidenecyclopropanes: Significant Influence of Substituents and Electronic Nature of Aryl Groups.
Authors: Zhang Yun‐Peng , Lu Jian‐Mei , Xu Guang‐Cai , Shi Min
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Rearrangement of Homoallylic Alcohols with Thallium(III): Diastereoselective Synthesis of Indans Bearing a β‐Hydroxy Ketone Moiety.
Authors: Silva Luiz F. Jr. , Quintiliano Samir A. P. , Craveiro Marcus V. , Vieira Fabiana Y. M. , Ferraz Helena M. C.
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Intermolecular Electrophilic O‐Amination of Alcohols.
Authors: Hassner Alfred , Patchornik Guy , Pradhan Tarun K. , Kumareswaran R. Kumareswaran R.
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of Functionalized THF and THP Through Au‐Catalyzed Cyclization of Acetylenic Alcohols.
Authors: Harkat Hassina , Weibel Jean‐Marc , Pale Patrick
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Photochemical Synthesis of Isomeric (E/Z)‐3‐Alkylidene‐3H‐isobenzofuranones.
Authors: Mor Satbir , Dhawan Som N. , Kapoor Mona , Dumar Devinder
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of β,γ‐Disubstituted α‐Methylene‐γ‐butyrolactams Starting from the Baylis—Hillman Adducts.
Authors: Lee Ka Young , Lee Young Ju , Kim Jae Nyoung
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
New Approaches to Polysubstituted Pyrroles and Pyrrolinones from α‐Cyanomethyl‐β‐ketoesters.
Authors: Demir Ayhan S. , Emrullahoglu Mustafa , Ardahan Guelben
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Coupling of Activated Esters to Gramines in the Presence of Ethyl Propiolate under Mild Conditions.
Authors: Jones David T. , Artman Gerald D. III , Williams Robert M.
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of N‐Benzylated Indole‐, Indazole‐ and Benzotriazole‐4,7‐diones
Authors: Marminon Christelle , Gentili Jacques , Barret Roland , Nebois Pascal
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A Novel Synthesis of 2‐Substituted Indole Derivatives: A Palladium Catalyzed Cross‐Coupling Reaction of Enol Triflate Derived from N‐Methyl‐2‐indolone with (Alkenyl)tributylstannane and Acetylene.
Authors: Wada Akimori , Shinmen Masaki , Uenishi Jun'ichi , Ito Masayoshi
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Study of the Behavior of p‐Bis{3‐[N,N‐dialkyl‐N‐(4‐hydroxybut‐2‐ynyl)ammonio] prop‐2‐ynyl}‐benzene Dichlorides in Relation to Aqueous Alkali. Double Intramolecular Recyclization of Benzo[5,6;5′,6′‐a,c]di(2,2‐dialkyl‐4‐hydroxymethyl)isoindolinium Dichlorides.
Authors: Chukhadzhyan E. O. , Gevorkyan A. R. , Khachatryan A. A. , Chukhadzhyan El. O. , Panosyan G. A.
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
1‐3‐Dipolar Cycloadditions of Trimethylsilyldiazomethane Revisited: Steric Demand of the Dipolarophile and the Influence on Product Distribution.
Authors: Simovic Dragan , Di Mingping , Marks Vered , Chatfield David C. , Rein Kathleen S.
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Regiospecific Synthesis of 1,5‐Disubstituted‐1H‐pyrazoles Containing Differentiated 3,4‐Dicarboxylic Acid Esters via Suzuki Coupling of the Corresponding 5‐Trifluoromethane Sulfonates.
Authors: Dragovich Peter S. , Bertolini Thomas M. , Ayida Benjamin K. , Li Lian‐Sheng , Murphy Douglas E. , Ruebsam Frank , Sun Zhongxiang , Zhou Yuefen
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Heterocyclic Analogues of 5,12‐Naphthacenequinone. Part 4. Synthesis of 4,11‐Dimethoxyanthra[2,3‐d]isoxazole‐5,10‐dione
Authors: Shchekotikhin A. E. , Luzikov Yu. N. , Buyanov V. N. , Preobrazhenskaya M. N.
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Palladium‐Catalyzed Alkynylation of 2‐ or 3‐Bromopyridine.
Authors: Zhang Weiwei , Cheng Jiang , Huang Zhengxu , Zhou Qingqing , Chen Xunmin , Qian Jianzhu
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
L‐Ascorbic Acid in Organic Synthesis: A Facile Synthesis of 4‐(Butenolide‐5‐methylidenyl)‐1,4‐dihydropyridines.
Authors: Bisht Surendra S. , Dwivedi Namrata , Tripathi Rama P.
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis and Biological Evaluation of 1,3,3,4‐Tetrasubstituted Pyrrolidine CCR5 Receptor Antagonists. Discovery of a Potent and Orally Bioavailable anti‐HIV Agent.
Authors: Ma Dawei , et al. et al.
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
CAN‐Catalyzed Three‐Component Reaction Between Anilines and Alkyl Vinyl Ethers: Stereoselective Synthesis of 2‐Methyl‐1,2,3,4‐tetrahydroquinolines and Studies on Their Aromatization.
Authors: Sridharan Vellaisamy , Avendano Carmen , Menendez J. Carlos
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Regio‐ and Stereoselective aza‐Diels—Alder Reaction of Ethyl Glyoxylate 4‐Methoxyphenylimine with 1,3‐Dienes in the Presence of BF3×Et2O. Evidence for a Non‐Concerted Mechanism.
Authors: Alves M. Jose , Azoia Nuno G. , Fortes A. Gil
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Vanillin Esters in Reactions with Indan‐1,3‐dione.
Authors: Kozlov N. G. , Basalaeva L. I.
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Characteristics of the Halogenation of 2‐Substituted 6‐Benzhydryl‐4(3H)‐pyrimidinones.
Authors: Novakov I. A. , Orlinson B. S. , Nawrozkij M. B.
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
An Unusual Oxidation—Dealkylation of 3,4‐Dihydropyrimidin‐2(1H)‐ones Mediated by Co(NO3) 2×6H2O/K2S2O8 in Aqueous Acetonitrile.
Authors: Shanmugam Pachaiyappan , Perumal Paramasivan T.
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
An Improved and Highly Convergent Synthesis of 4‐Substituted‐pyrido[2,3‐d]pyrimidin‐7‐ones.
Authors: Yan Hongxing , Boehm Jeffrey C. , Jin Qi , Kasparec Jiri , Li Huijie , Zhu Chongjie , Widdowson Katherine L. , Callahan James F. , Wan Zehong
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A Novel One‐Pot Procedure for Preparation of Some New Condensed Pyrido[2,3‐d]pyrimidine(1H,3H)‐2,4‐diones.
Authors: Azizian Javad , Mohammadizadeh Mohammad R. , Mohammadi Ali A. , Karimi Ali R. , Teimouri Fatemeh
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of Novel 2,3‐Substituted Quinazolin‐4‐ones by Condensation of Alkyl or Aromatic Diamines with 5‐(N‐Arylimino)‐4‐chloro‐5H‐1,2,3‐dithiazoles.
Authors: Pereira Maria de Fatima , Thiery Valerie , Besson Thierry
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Syntheses of New 1,2‐, 1,3‐, and 1,4‐Diazine Derivatives. Part 1. Synthesis of Diazinylarylacetonitriles.
Authors: Wisterowicz K. , Foks H.
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Cyclic Polysulfides Fused to Polyaromatics.
Authors: Alam Ashraful , Kon‐no Masaru , Ogawa Satoshi , Sato Ryu
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
First Synthesis of Picealactone C. A New Route Toward Taxodione‐Related Terpenoids from Abietic Acid.
Authors: Alvarez‐Manzaneda Enrique , Chahboun Rachid , Cabrera Eduardo , Alvarez Esteban , Alvarez‐Manzaneda Ramon , Lachkar Mohammed , Messouri Ibtissam
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A Cross‐Metathesis Route to Functionalized α‐Methyl α‐Substituted Amino Acids.
Authors: Storcken Roy P. M. , Panella Lavinia , van Delft Floris L. , Kaptein Bernard , Broxterman Quirinus B. , Schoemaker Hans E. , Rutjes Floris P. J. T.
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A Bacterial Chitinase Acts as Catalyst for Synthesis of the N‐Linked Oligosaccharide Core Trisaccharide by Employing a Sugar Oxazoline Substrate.
Authors: Kobayashi Atsushi , Kuwata Hideyuki , Kohri Michinari , Izumi Ryuko , Watanabe Takeshi , Shoda Shin‐ichiro
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of Novel Galactopyranosyl‐Derived Spiro Barbiturates.
Authors: Ingle V. N. , Gaidhane P. K. , Dutta S. S. , Naha P. P. , Sengupta M. S.
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Regioselective Oxidative Cleavage of Benzylidene Acetals: Synthesis of Highly Functionalized Chiral Intermediates.
Authors: Senthilkumar Pon Minor , Aravind Appu , Baskaran Sundarababu
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Anthranoyl‐Substituted Norditerpene Alkaloids from Aconitum vulparia Rchb. and Their Cytotoxic Activities.
Authors: Csupor Dezso , Forgo Peter , Zupko Istvan , Szabo Pal , Hohmann Judit
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
First Enantiospecific Total Synthesis of the Important Biogenetic Intermediates, (+)‐Polyneuridine(Ia) and (+)‐Polyneuridine Aldehyde(IIa), as well as 16‐Epi‐vellosimine (IIb) and Macusine A (Ib).
Authors: Yin Wenyuan , Ma Jun , Rivas Felix M. , Cook James M.
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A New, Simple and Efficient Method for the Synthesis of 7‐Aza‐bicyclo[2.2.1]heptane Derivatives: Formal Total Synthesis of Epibatidine.
Authors: Gomez‐Sanchez Elena , Marco‐Contelles Jose
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Aporphine Alkaloid Synthesis and Diversification via Direct Arylation.
Authors: Lafrance Marc , Blaquiere Nicole , Fagnou Keith
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Asymmetric Total Synthesis of Martinelline and Martinellic Acid.
Authors: Ikeda Shuhei , Shibuya Masatoshi , Iwabuchi Yoshiharu
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Isolation of Tetraprenyltoluquinols from the Brown Alga Sargassum thunbergii.
Authors: Seo Youngwan , Park Ki Eui , Kim You Ah , Lee Hee‐Jung , Yoo Jong‐Su , Ahn Jong‐Woong , Lee Burm‐Jong
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis and Biological Activity of New 1‐[4‐(Substituted)‐piperazin‐1‐ylmethyl]‐1H‐benzotriazole.
Authors: He Feng‐qi , Liu Xing‐hai , Wang Bao‐lei , Li Zheng‐ming
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis, Properties and Chemistry of Xenon(II) Fluoride
Authors: Tramsek Melita , Zemva Boris
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Time‐Resolved and Operando XAS Studies on Heterogeneous Catalysts ‐ From the Gas Phase Towards Reactions in Supercritical Fluids
Authors: Grunwaldt Jan‐Dierk , Baiker Alfons
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
1‐Haloalk‐1‐ynes and Alk‐1‐yn‐1‐ols
Authors: Witulski B. , Alayrac C.
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
1‐Heteroatom‐functionalized 2‐Haloacetylenes
Authors: Witulski B. , Alayrac C.
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Dihaloacetylenes
Authors: Witulski B. , Alayrac C.
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
1,1‐Bisazo‐, 1,1‐Diazido‐, and 1,1‐Dinitroalk‐1‐enes
Authors: Banert K.
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
1,1‐Bis(organooxy)allenes,1,1‐ Bis(organooxy)butatrienes, 1‐(Organooxy)‐1‐siloxyallenes, and 1‐(Organooxy)allen‐1‐olates
Authors: Zimmer R.
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthetic Ion Channels in Bilayer Membranes
Authors: Fyles Thomas M.
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Transition Metal Complexes as Molecular Machine Prototypes
Authors: Champin Benoit , Mobian Pierre , Sauvage Jean‐Pierre
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Carbohydrate‐Based Scaffolds in Drug Discovery
Authors: Becker Bernd , Condie Glenn C. , Le Giang Thanh , Meutermans Wim
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Biologically Active, Synthetic Ion Transporters
Authors: Gokel George W. , Carasel I. Alexandru
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Post‐Polymerization of Preorganized Assemblies for Creating Shape‐Controlled Functional Materials
Authors: Sada Kazuki , Takeuchi Masayuki , Fujita Norifumi , Numata Munenori , Shinkai Seiji
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of a Highly Potent Antitumor Saponin OSW‐1 and Its Analogues
Authors: Morzycki Jacek W. , Wojtkielewicz Agnieszka
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Reaction Chemistry of Gossypol and Its Derivatives
Authors: Kenar James A.
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Mesoionic Compounds: An Unconventional Class of Aromatic Heterocycles
Authors: Badami Bharati V.
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Pyrazolo[4,3‐e][1,2,4]triazolo[1,5‐c]pyrimidine Template: Organic and Medicinal Chemistry Approach
Authors: Baraldi Pier Giovanni , Tabrizi Mojgan Aghazadeh , Romagnoli Romeo , El‐Kashef Hussein , Preti Delia , Bovero Andrea , Fruttarolo Francesca , Gordaliza Marina , Borea Pier Andrea
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Efficient Radical Addition of Tertiary Amines to Alkenes Using Photochemical Electron Transfer
Authors: Hoffmann Norbert , Bertrand Samuel , Marinkovic Sinisa , Pesch Jens
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Confinement Effects of Cyclodextrin on the Photodynamics of Few Selected Systems
Authors: Organero J. A. , Tormo L. , Sanz M. , Santos L. , Douhal A.
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Applications of Functionalized Ionic Liquids
Authors: Li Xuehui , Zhao Dongbin , Fei Zhaofu , Wang Lefu
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
1,1‐Bis(nitrogen‐functionalized)allenes and Butatrienes
Authors: Zimmer R.
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
How to Reach Stereogenic Trifluoromethylated Carbon? En Route to the “Grail” of the Asymmetric Trifluoromethylation Reaction
Authors: Billard Thierry , Langlois Bernard R.
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Palifermin, a Keratinocyte Growth Factor That Reduces Oral Mucositis After Stem Cell Transplant for Hematological Malignancies
Authors: Beaven Anne W. , Shea Thomas C.
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
The Chemistry of Mercapto‐ and Thione‐Substituted 1,2,4‐Triazoles and Their Utility in Heterocyclic Synthesis
Authors: Shaker Raafat M.
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Design and Synthesis of Heterocycle‐Fused Enediyne Prodrugs Activable at Will
Authors: Banfi Luca , Basso Andrea , Guanti Giuseppe , Riva Renata
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
1,2,3‐Dithiazole Chemistry in Heterocyclic Synthesis
Authors: Christoforou Irene C. , Koutentis Panayiotis A. , Michaelidou Sophia S.
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of Azaheterocycles by One‐Electron Reduction of Oximes
Authors: Narasaka Koichi , Kitamura Mitsuru
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Thermally Responsive Polymer Vesicles
Authors: Morishima Yotaro
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Recent Approaches Towards the Asymmetric Synthesis of α,α‐Disubstituted α‐Amino Acids
Authors: Vogt Henning , Braese Stefan
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Electroluminescence of Organic Materials: Base Principles
Authors: Le Barny Pierre
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Site Requirements in the Kinetics of Alkane Transformations Catalyzed by Metals
Authors: Garin Francois
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Enzymatic and Chemical Cleavage Methods to Identify Genetic Variation
Authors: Bui Chinh T. , Nicolas Emmanuelle , Sallmann Georgina , Chiotis Maria , Lambrinakos Andreana , Rees Kylee , Trounce Ian , Cotton Richard G. H. , Blakesley Lauryn , Godwin Andrew K. , et al. et al.
Published: May 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Finite‐element model for creep buckling analysis of beam‐type structures
Authors: Lanc Domagoj , Turkalj Goran , Brnić Josip
Published: May 2007

This paper presents a one‐dimensional finite element for creep buckling analysis of structures comprised of straight and prismatic beam members. Spatial displacements and rotations are allowed to be large while strains are assumed to be small. Material is assumed to be homogenous and isotropic. The corresponding equilibrium equations are formulated in the framework of co‐rotational description, using the virtual work principle. In contrast to conventional co‐rotational formulation, which is linear on element level and unable to model Wagner effect, in this paper an additional nonlinear part of stiffness matrix is evaluated and added to standard elastic stiffness.
Implementation of developed numerical algorithm is demonstrated through few test problems. Copyright © 2007 John Wiley & Sons, Ltd.
Scanning Tunneling Microscopy and Spectroscopy Studies of 4‐Methyl‐ 4′‐(n‐mercaptoalkyl)biphenyls on Au(111)‐(1×1)
Authors: Su Gujin J. , Aguilar‐Sanchez Rocio , Li Zhihai , Pobelov Ilya , Homberger Melanie , Simon Ulrich , Wandlowski Thomas
Published: May 2007

4‐Methyl‐4′‐(n‐mercaptoalkyl)biphenyl (CH3C6H4C6H4(CH2)nSH, n=3–6, BPn) monolayers assembled on Au(111)‐(1×1) in 1,3,5,‐trimethylbenzene (TMB) at various temperatures are studied by scanning tunneling microscopy (STM) and scanning tunneling spectroscopy (STS). High resolution STM images reveal that BP3 and BP5 form a (${\sqrt 3 }$×2${\sqrt 3 }$) repeating motif superimposed on a temperature‐dependent Moire pattern. BP4 and BP6 adlayers are characterized by a coexisting (2${\sqrt 3 }$×5${\sqrt 3 }$) majority phase and a temperature‐dependent (3×p${\sqrt 3 }$) minority phase. Assembly at 60 °C or 90 °C leads to p=5. Compression of the adlayer was found at higher temperatures. Combined with high‐resolution structure experiments, the electronic characteristics of BP3 and BP4 self‐assembled monolayers (SAMs) were studied by monitoring current–distance (iT–Δz) and current–voltage (iT–Ebias) characteristics in TMB employing a gold STM tip|BPn|Au(111)‐(1×1) configuration. The semilogarithmic (iT–Δz) plots yielded three linear regions in the range 10 pA≤iT≤20 μA, which were attributed to the different positions of the STM tip with respect to the molecular adlayer (I outside, II in contact with and/or within the adlayer, and III just before the formation of Au–Au nanocontacts). The effective decay constants κeff and the corresponding barrier heights ϕeff decrease with decreasing tip–substrate distance. The iT–Ebias curves at low bias voltages are represented by the Simmons tunneling model. Based on measurements in the high current limit, the electric field strength of the dielectric breakdown was estimated to range between |0.85±0.05|×109 V m−1 and |1.5±0.1|×109 V m−1.
Mechanical Properties of Carbon Nanomaterials
Authors: Hayashi Takuya , Kim Yoong Ahm , Natsuki Toshiaki , Endo Morinobu
Published: May 2007

Carbon nanomaterials show a variety of interesting chemical and physical properties. In this Minireview we focus on the mechanical properties of carbon nanomaterilas with emphasis on carbon nanotubes and their composite materials. We introduce some recently developed components made of carbon nanotube composite materials and outline their importance for applications in everyday life.
Evaluation of a single‐platform microcapillary flow cytometer for enumeration of absolute CD4+ T‐lymphocyte counts in HIV‐1 infected Thai patients
Authors: Pattanapanyasat Kovit , Phuang‐Ngern Yuwadee , Lerdwana Surada , Wasinrapee Punneeporn , Sakulploy Natthaga , Noulsri Egarit , Thepthai Charin , McNicholl Janet M.
Published: May 2007

Background:

Various assays are used to enumerate peripheral blood absolute CD4+ T‐lymphocytes. Flow cytometry is considered the gold standard for this purpose. However, the high cost of available flow cytometers and monoclonal antibody reagents make it difficult to implement such methods in the resource‐poor settings. In this study, we evaluated a cheaper, recently developed single‐platform microcapillary cytometer for CD4+ T‐lymphocyte enumeration, the personal cell analyzer (PCA), from Guava® Technologies.

Methods:

CD4+ and CD8+ T‐lymphocyte counts in whole blood samples from 250 HIV‐1 infected Thais were determined, using a two‐color reagent kit and the Guava PCA, and compared with the results obtained with two reference microbead‐based methods from Becton Dickinson Biosciences: the three‐color TruCOUNT™ tube method and the two‐color FACSCount™ method. Statistical correlations and agreements were determined using linear correlation and Bland–Altman analysis.

Results:

Absolute CD4+ T‐lymphocyte counts obtained using the Guava PCA method highly correlated with those obtained using TruCOUNT method (R2 = 0.95, mean bias +13.1 cells/μl, limit of agreement [LOA] −101.8 to +168.3 cells/μl). Absolute CD8+ T‐lymphocyte counts obtained using the Guava PCA method also highly correlated with those obtained with the two reference methods (R2 = 0.92 and 0.88, respectively).

Conclusion:

This study shows that the enumeration of CD4+ T‐lymphocytes using the Guava microcapillary cytometer PCA method performed well when compared with the two reference bead‐based methods. However, like the two reference methods, this new method needs substantial technical expertise. © 2007 Clinical Cytometry Society.
Does cyclosporin A affect CCR5 and CXCR4 expression in primary HIV‐1‐infected patients?
Authors: Biswas Priscilla , Galli Andrea , Galli Laura , Din Chiara Tassan , Vecchi Andrea , Malnati Mauro , Lazzarin Adriano , Tambussi Giuseppe
Published: May 2007

Background:

CCR5 and CXCR4 are the major coreceptors of HIV required for successful viral entry. No information exists on the effect of cyclosporin A (CsA) on expression of CCR5 and CXCR4. A longitudinal study of the coreceptors' expression in freshly isolated peripheral blood mononuclear cells (PBMC) of patients with primary HIV infection (PHI) was performed.

Methods:

Patients received highly active antiretroviral therapy (HAART) alone (n = 7) or with CsA (HAART + CsA) (n = 8). Flow cytometric data were analyzed at T0 (baseline), two (T2), six (T6), and twelve (T12) months after therapy initiation.

Results:

At T0 PHI subjects presented a statistically significant higher count and percentage of CD8+CCR5+ lymphocytes compared to healthy donors (HD) (mean ±± SD, 2,240 ±± 1,998 vs 181 ±± 89 cells/μl). Conversely, CD4+CXCR4+ lymphocytes were less abundant in PHI than in HD (443 ±± 337 vs 673 ±± 339 cells/μl), whereas CD4+CCR5+ lymphocytes were substantially comparable (169 ±± 167 vs 126 ±± 60 cells/μl). In the follow up no differences between HAART and HAART + CsA groups reached statistical significance in CD4 lymphocytes. CD4+CCR5– lymphocytes displayed a rapid recovery after therapy initiation, similarly to the CD4+CXCR4+ subset. In CD8 lymphocytes a statistically significant difference between HAART and HAART + CsA patients occurred at T2 when HAART + CsA patients presented a lower absolute count of the CD8+CXCR4+ subset compared to the HAART group. The major change after therapy initiation in all PHI patients was a striking drop of CD8+CCR5+ lymphocytes; moreover, the CD8+CXCR4– subset behaved similarly. The decrement of CD8+CCR5+ lymphocytes paralleled the decline of viremia and CD8+CD38+ lymphocytes, with the sharpest slope at T2. Conversely, RANTES levels increased at T2 and remained elevated during the follow up.

Conclusions:

CsA cotreatment in PHI patients appears not to substantially modify HIV coreceptors' expression in PBMC. However, this novel piece of information should be used with caution, since this was not a randomized study between the HAART and the HAART + CsA groups. © 2007 Clinical Cytometry Society
Bacillus subtilis spores: A novel microparticle adjuvant which can instruct a balanced Th1 and Th2 immune response to specific antigen
Authors: Barnes Andrew G. C. , Cerovic Vuk , Hobson Philip S. , Klavinskis Linda S.
Published: May 2007

There is a current need for safe, cheap, and effective vaccine adjuvants, to combine with sub‐unit antigens to enhance their immunogenicity. In this study we have used probiotic Bacillus subtilis spores, known to be safe and fully tolerated by ingestion in man, and explored their ability to influence the magnitude and diversity of immune responses induced against two model antigens, tetanus toxoid fragment C (TT) and ovalbumin (OVA) in mice. The results show that B. subtilis spores not only increased antibody and T cell responses to a co‐administered soluble antigen, but also broadened them, to include both antigen‐specific CD4+ and CD8+ T cell responses as well as complement and non‐complement fixing antibody isotypes. Furthermore, following intranasal immunization, spores augmented specific IgA to co‐administered antigen both in the local respiratory and distal vaginal mucosa, as well as increased antigen‐specific IgG antibody in draining LN and blood. Collectively, these data demonstrate that naturally occurring, non‐pathogenic, non‐commensal spores of B. subtilis both instruct and augment polyvalent immune responses and highlight their clinical potential in future vaccines to generate broad‐based immunity.
CpG DNA stimulates autoreactive immature B cells in the bone marrow
Authors: Azulay‐Debby Hilla , Edry Efrat , Melamed Doron
Published: May 2007

Polyclonal activation of developing B cells is an injurious process, because most of these cells are nontolerant and express autoreactive receptors. CpG DNA is a polyclonal activator of mature B cells, but its effect on developing B cells is unclear. We tested whether developing, nontolerant B cells are responsive to mitogenic stimulation by CpG DNA and whether such a stimulus can interfere with the establishment of central tolerance. We found that developing B cells express Toll‐like receptor 9 and undergo a polyclonal response to CpG DNA stimulation, as revealed by proliferation and differentiation to antibody‐producing cells. In vitro and ex vivo experiments revealed that stimulation with CpG DNA protects immature B cells from negative selection imposed by apoptosis and receptor editing and results in the production of autoantibodies. Finally, we found that in vivo administration of CpG DNA activates immature B cells in the bone marrow and suppresses the expression of recombination‐activating genes in a mouse model of central tolerance and receptor editing. These results suggest that mitogenic signals provided by CpG DNA stimulate nontolerant immature B cells in the bone marrow and have the potential to interfere with central tolerance.
Human peritoneal macrophages show functional characteristics of M‐CSF‐driven anti‐inflammatory type 2 macrophages
Authors: Xu Wei , Schlagwein Nicole , Roos Anja , van den Berg Timo K. , Daha Mohamed R. , van Kooten Cees
Published: May 2007

We have recently shown that in vitro polarized M‐CSF‐driven anti‐inflammatory macrophages (MΦ2) have the unique capacity to preferentially bind and ingest early apoptotic cells. However, these data are based on in vitro polarized cells and it is unclear whether MΦ2‐like cells exist in vivo. Here we used CD163 as a cell surface marker to distinguish MΦ2 from the pro‐inflammatory MΦ1. We show that human peritoneal MΦ (pMΦ) freshly isolated from patients on peritoneal dialysis have the phenotypical characteristics of MΦ2, including CD163 surface expression and lack of CD16. Like MΦ2, pMΦ have the capacity for endocytosis and macropinocytosis, are able to preferentially bind and ingest early apoptotic cells, and produce large amounts of IL‐10 upon stimulation with LPS. Moreover, upon LPS stimulation both pMΦ and MΦ2 down‐regulate CD86, resulting in a reduced capacity to stimulate proliferation of allogeneic T cells and an inhibition of Th1 cytokine release of these T cells. Our data provide the evidence for the first time that in vitro polarized MΦ2 exist in vivo, and human pMΦ resemble the anti‐inflammatory MΦ2. We propose that pMΦ have the potential to maintain an anti‐inflammatory condition in the peritoneal cavity.
Role of TGF‐β and PGE2 in T cell responses during Plasmodium yoelii infection
Authors: Ocaña‐Morgner Carlos , Wong Kurt A. , Lega Flavia , Dotor Javier , Borras‐Cuesta Francisco , Rodriguez Ana
Published: May 2007

During an acute blood‐stage malaria infection, T cell responses to malaria and other bystander antigens are inhibited. Plasmodium infection induces strong cytokine responses that facilitate parasite clearance but may interfere with T cell functions, as some of the soluble immune mediators induced are also general inhibitors of T cell responses. Using a malaria mouse model, we have analyzed the cytokines produced by dendritic cells in response to P. yoelii infection that have potential T cell inhibitory activity. We found that during acute infection DC migrate to the spleen and secrete TGF‐β, prostaglandin E2 (PGE2) and IL‐10. We have analyzed the role of these general T cell inhibitors in a particular T cell response of evident importance in malaria infections: the CD8+ T cells generated against the liver‐stage of the disease. During blood‐stage infection, inhibition of the activity of TGF‐β and PGE2 restores the CD8+ T cell responses generated by sporozoites, increasing protection against re‐infection. Our findings suggest that the strong cytokine response induced by blood‐stage P. yoelii infection affects host T cell responses, inhibiting protective CD8+ T cells against the liver‐stage of the disease.
Response of seismically isolated buildings considering poundings
Authors: Komodromos Petros , Polycarpou Panayiotis C. , Papaloizou Loizos , Phocas Marios C.
Published: May 2007

Numerical simulations and parametric studies have been used to investigate the influence of potential poundings of seismically isolated buildings with adjacent structures on the effectiveness of seismic isolation. Poundings are assumed to occur at the isolation level between the seismically isolated building and the surrounding moat wall. After assessing some common force‐based impact models, a variation of the linear viscoelastic impact model is proposed to avoid tensile impact forces during detachment, while enabling the consideration of permanent plastic deformations at the vicinity of the impact. A large number of numerical simulations of seismically isolated buildings with different characteristics have been conducted under six earthquake excitations in order to investigate the influence of various design parameters and conditions on the peak floor accelerations and interstorey deflections during poundings. The numerical simulations demonstrate that poundings may substantially increase floor accelerations, especially t the base floor where impacts occur. Higher modes of vibration are excided during poundings, increasing the interstorey deflections, instead of retaining an almost rigid‐body motion of the superstructure, which is aimed with seismic isolation. Impact stiffness seems to affect significantly the acceleration response at the isolation level, while the displacement response is more insensitive to the variation of the impact stiffness. Finally, the results indicate that providing excessive flexibility at the isolation system to minimize the floor accelerations may lead to a building vulnerable to poundings, if the available seismic gap is limited. Copyright © 2007 John Wiley & Sons, Ltd.
A new model to analyse the impact of woody riparian vegetation on the geotechnical stability of riverbanks
Authors: Wiel Marco J. Van De , Darby Stephen E.
Published: May 2007

We present a geotechnical stability analysis for the planar failure of riverbanks, which incorporates the effects of root reinforcement and surcharge for mature stands of woody riparian vegetation. The analysis relies on a new method of representing the root distribution in the soil, which evaluates the effects of the vegetation's position on the bank. The model is used in a series of sensitivity analyses performed for a wide range of bank morphological (bank slope and height) and sedimentological (bank cohesion and friction angle) conditions, enabling discrimination of the types of bank environment for which vegetation has an effect on bank stability. The results indicate that woody vegetation elements have a maximal impact on bank stability when they are located at the ends of the incipient failure plane (i.e. at the bank toe or at the intersection of the failure plane with the floodplain) and that vegetation has a greater effect on net bank stability when it is growing on low, shallow, banks comprised of weakly cohesive sediments. However, the magnitude of these effects is limited, with vegetation typically inducing changes (relative to non‐vegetated banks) in simulated factors of safety of less than 5%. If correct, this suggests that the well documented effects of vegetation on channel morphology must be related to alternative process mechanisms (such as the interaction of vegetation with river flows) rather than the mechanical effects of vegetation on bank failure, except in special cases where the equivalent non‐vegetated bank has a highly marginal stability status. Copyright © 2007 John Wiley & Sons, Ltd.