bluuebunny/crossref_metadata_2025 huggingface dataset:
A COMPARATIVE STUDY OF ANESTHETIC BLOCK TECHNIQUES (V-BLOCK VS. H-BLOCK) FOR REMOVAL OF INGROWN TOENAIL
Authors: FAROOQI A , ZAHEER F , SALMAN S , SADIA . , SHAIKH SN , RIMSHA S
Published: July 2024

Ingrown toenail (onychocryptosis) is a common and painful condition often requiring surgical intervention. Adequate local anaesthesia is crucial for patient comfort and surgical success. However, the optimal anaesthetic technique for this procedure remains debated. Objectives: This study aimed to evaluate and compare the anaesthetic efficacy, patient comfort, onset and duration of anaesthesia, and occurrence of complications between the V-block and H-block techniques during surgical procedures for ingrown toenail removal. Methods: After ethical approval, an open-label randomised control trial was conducted at Ruth PFAU Civil Hospital, Dow University of Health Sciences, Karachi. One hundred eighty-eight patients, aged 18 and above, with type II, III, and IV onychocryptosis were included. Patients were randomly assigned to either Group A (H-technique, n=94) or Group B (V-technique, n=94). Local anaesthesia was administered using 5 ml of 2% Xylocaine diluted in 5 ml of distilled water. Pain severity, numbness, and loss of sensation were assessed at 2, 5, and 10 minutes post-injection. Data were analysed using SPSS version 26. Results: Group A (H-technique) had a significantly younger average age (35.12±9.8 years) compared to Group B (39.77±13.01 years). Gender distribution differed significantly, but weight did not. At 2 minutes, Group B reported more pain (90% vs. 86.5%, P=0.045). At 5 and 10 minutes, Group B showed higher numbness and loss of sensation, indicating more comprehensive anaesthesia. Efficacy at 10 minutes was higher in Group B (44% vs. 39%, P=0.045), with similar trends at 20 minutes but no significant difference. Conclusion: The V-block technique offers rapid onset and effective pain relief for routine procedures, while the H-block technique provides more comprehensive and sustained anaesthesia for complex surgeries. The selection of anaesthetic techniques should be based on the surgical context to optimise patient outcomes. Further research is recommended to enhance these techniques' efficacy and minimise complications.
In vitro antioxidant and anti-diabetic properties of cookies produced from wheat and soybean composite flour
Authors: Alagbe Iyanu Caleb ,   Department of Nutrition and Dietetics, Ladoke Akintola University of Technology, Ogbomosho, Nigeria., Malomo Sunday Abiodun ,   Department of Nutrition and Dietetics, Federal University of Technology, Akure, Nigeria.
Published: July 2024

Composite flours are formulated from wheat and soybean, which were mixed together to formulate four blends WSY 1 (100%), WSY 2 (80%-20%), WSY 3 (70%-30%), WSY 4 (60%-40%), respectively. The flours and the cookies were investigated for their proximate composition, amino acid profiles, in vitro bioactivities (antioxidant and anti-diabetic properties) and the consumer acceptability of the cookies using standard methods. The proximate compositions of the composite flour were greatly improved during the baking process into cookie with the carbohydrate, protein and fat contents ranges of 69.64-71.44%, 9.13-23.26% and 2.99-9.82%, respectively. The amino acid profiles of the cookies were well established with high biological values (>70%) in terms of their essential, non-essential and hydrophobic amino acids while glutamic acid served as the most abundant amino acid (19.15 – 28.69%) present in each of the cookies. The cookie samples were able to scavenge free radicals, reduced and chelate metallic ions when compared with a standard ascorbic acid, a well-known antioxidant. However, the in-vitro anti-diabetic properties of the cookie samples were revealed when they inhibited the activities of α-amylase and α-glucosidase when compared with a standard acarbose, a well-known anti-diabetic drug. Overall, the cookie sample from the 60% wheat and 40% soybean composite flour was acceptable to the consumers as shown by their ratings and perceptions, which could be highly found useful as potential bioactive antioxidant and anti-diabetic agents in the management of diabetes mellitus.
Nutritional Indices, Haematological and Biochemical Evaluation of Albino Rats Fed with Crunchy Snack Produced from Corn, Red Kidney Beans and Onion Flour
Authors: Adegbanke Omolara Racheal ,   Department of Food Science and Technology, Federal University of Technology, P.M.B. 704, Akure, Ondo State, Nigeria., Jeremiah Oluchi Mercy ,   Department of Food Science and Technology, Federal University of Technology, P.M.B. 704, Akure, Ondo State, Nigeria.
Published: July 2024

Corn is one of the most versatile grains with nutritional benefits and can be found all over the world. The use of indigenous raw materials like red kidney beans and onion serves as an alternative means to improve the nutritional and sensory qualities of corn flour without reducing the viability of its nutritional attributes. This study investigated the haematological, biochemical evaluation and nutritional indices of albino rats fed with crunchy snack produced from corn, red kidney beans and onion flour and the sensory evaluation of the formulated product using standard methods. White maize, red kidney beans and onions were obtained from Shasha market, Akure, Nigeria, other ingredients such as salt, sugar and pepper were purchased from Oba market, Akure, Nigeria. They were prepared at different proportions of WRKBO1 (white maize flour 70%, red kidney beans 25% and onion flour 5%), WRKBO2 (white maize flour 70%, red kidney beans 15% and onion flour 15%) and WRKBO3 (white maize flour 70%, red kidney beans 20% and onion flour 10%). The formulated blends were used to produce crunchy snacks in the laboratory of Food Science and Technology FUTA, Akure, Ondo State, Nigeria. The proximate analysis results showed that the moisture, fiber, protein and fat contents were higher in the formulated crunchy snacks than in the control snack. The following range of values were obtained for moisture (4.03-15.33%), fiber (14.92-18.45%) and fat (1.91-5.06%) and sample WRKBO3 had the highest value of 15.33%, 18.45% and 5.06% respectively and was significantly different (p < 0.05) from the control. The protein content value ranged from (3.33-9.52%); sample WRKBO1 had the highest value of 9.52% and was significantly different from the control. The result of the sensory evaluation was based on a nine-point hedonic scale and it was observed that sample WRKBO1 (white maize flour 70%, red kidney beans 25% and onion flour 5%) was more acceptable to the panelists.
Physicochemical and Antioxidant Properties of Cocoyam, African Yam Bean and Watermelon Rind Flour Blends and Consumer Acceptability of its Cake
Authors: Bello Florence A. ,   Department of Food Science and Technology, Faculty of Agriculture, University of Uyo, Uyo, Nigeria., Oladeji Babatunde S. ,   Department of Food Science and Technology, Faculty of Agriculture, University of Calabar, Calabar, Nigeria.
Published: July 2024

This study aimed to determine the quality of the flour blends and cakes developed from underutilized indigenous crops supplemented with food processing waste. The variables were cocoyam flour (CF), African yam bean flour (AYBF) and watermelon rind powder (WMRP) with their constraints 65-80%, 5-30% and 5-15%, respectively. Sixteen samples were generated using design expert software and subjected to proximate analysis. The best three samples were selected based on the highest protein and crude fibre content and were further evaluated for antioxidant, antinutrient, functional properties and pasting properties. Cakes were also developed and assessed for sensory properties. The incorporation of AYBF and WMRP significantly (p<0.05) led to the increase in ash, crude protein and crude fibre. The antioxidant properties in the flour blend samples showed significant (p<0.05) increase. The higher foaming capacity and stability of the samples were observed as well as final viscosity of the flour blends. Cake made from 70.71% CF, 24.29% AYBF and 5% WMRP (Sample 7) had the highest overall acceptability and competing favourably with cake made from wheat flour (control).
In vitro Protein and Starch Digestibility, Nutritional and Bioactive Properties of Elekute (A Maize-Based Snack) Substituted with Catfish (Clarias gariepinus)
Authors: Taiwo-Olabode Folasade A. ,   Department of Food Science and Technology, Federal University of Technology, Akure, Nigeria., Ukeyima Moses T. , Enujiugha Victor N. ,   Department of Nutrition and Dietetics, Joseph Sarwuan Tarka University, Makurdi, Nigeria.,   Department of Food Science and Technology, Federal University of Technology, Akure, Nigeria
Published: July 2024

One of the popular and most commonly consumed maize-based snacks is elekute, which is made from maize powder mixed with spices and other ingredients depending on individual preferences. In this study, elekute was prepared by substituting maize with catfish powder at graded ratios (100% maize as control; 90:10; 80:20; 70:30; 60:40; 50:50 maize:catfish, respectively). The nutrients, anti-nutrients, antioxidants, as well as in vitro protein and starch digestibility, were all assayed in the respective samples. Results showed higher protein contents with increased substitution (highest was in 60:40). Mineral composition also increased with increased substitution. The phytic acid, oxalate and tannins in the samples reduced with higher substitution level. There was significant difference among the samples in oil absorption capacity, emulsion capacity, swelling capacity, and foaming capacity, but no significant difference in water absorption capacity, bulk density, and least gelation capacity. The antioxidant properties of the Elekute were enhanced with the inclusion of catfish flour. The alpha amylase inhibitory activity was found to increase slightly with the addition of catfish flour up to 20% (80:20). The alpha glucosidase inhibitory activity of the Elekute was also found to be highest at 20% inclusion of the catfish flour (80:20). Enrichment of Elekute snack by adding catfish flour improved the nutritional quality of this maize-based snack with high level of acceptance from the taste panelists.
Scientific Reasonings Regarding the Multiverse and Its Implications
Authors: Peng Kangze
Published: July 2024

The multiverse has been a heated topic under discussion as it belongs to a scientific concept, yet still has strong philosophical implications as direct evidence can hardly be gathered. This research analyzes the likelihood of the multiverse using classical scientific reasoning models, including falsification and the paradox of grue. The paper also discusses the impact of the multiverse on our free will, covering the notions of the time sequence, self, and the logic behind scientific developments. The paper concludes that the multiverse is so far rendered pseudoscience, and the situation may only change when science further develops. Although the multiverse is a theory that strongly challenges the notion of free will, the paper concludes that we should believe we possess free will to prevent the culture war and preserve all human emotions.
Stop Updating: A Textual Analysis of Chinese Viewers Towards the Video of Bilibili Vloggers Announcement
Authors: Zhang Pengcheng
Published: July 2024

Bilibili, a video sharing website where users can view and add overlaid commentary on videos has become one of the major video sharing platforms in China. In early 2023, a phenomenon emerged on Bilibili where vloggers began announcing stop updating, indicating their intention to cease uploading new content. This phenomenon immediately sparked widespread discussions on the internet and within society at large. This study employs text analysis to gain insights into how users on Bilibili reacted and responded to vloggers announcing stop updating. The research identifies five dimensions characterizing the users responses: (1) attitudes towards the ecosystem; (2) attitudes towards Bilibili; (3) attitudes towards advertising; (4) attitudes towards vloggers; and (5) attitudes towards other users. The findings of this research illuminate the relationships among Bilibili, content creators, users, and how these dynamics influence content production, dissemination, and monetization on the platform. Additionally, the results offer insights into the behaviors of content creators and users on the platform. Furthermore, this research unveils the business models of Bilibili, particularly concerning aspects related to advertising, sponsorship, and the profitability of content creators.
Teacher Well-being: A Literature Review
Authors: Mo Sha
Published: July 2024

Teachers' well-being plays an salient role in teachers' professional development, students' academic success and psychological health, and a positive school atmosphere. However, current research on this issue is largely fragmented, so it is important to assess what has been studied and gain meaningful insights through a structural review of the literature. This literature review analyzes the existing research on teacher well-being from theories, antecedents, outcomes, and interventions of teacher well-being. According to the literature review, four theoretical models are applied to analyze antecedents and outcomes of teacher well-being. Personal and organizational antecedents have positive or negative influences on teacher well-being. Teachers with high levels of well-being can improve teacher professional development, students academic success and mental health, and create supportive learning atmospheres and environments in school settings. Training in class management ability, emotional regulation ability, coping ability, interpersonal ability and work-life balance ability have become more critical and beneficial to teachers. Implications and recommendations for future research are proposed.
Research on the Impact of Regional Differences on Promoting Educational Equity
Authors: Huangfu Rongrong
Published: July 2024

In recent years, the issue of educational inequality has received widespread attention. Studying the issue of educational inequality not only helps to reveal its causes and mechanisms but also provides the scientific basis for policy-making, promotes rational distribution and utilization of educational resources, as well as improves the quality and efficiency of education. This article examines the present state of educational progress across various geographical areas, the manifestations of educational inequality, the reasons, and countermeasures. Many factors affect educational equity, such as natural factors, financial investment, resource allocation, public awareness, and education's importance. Based on this, this article proposes the following suggestions: Local governments and schools should actively improve and implement relevant existing policies. The government and society should strive to narrow the gap between the rich and the poor in the regions and increase financial investment in local education. The government and schools should gradually optimize the allocation structure of educational resources and ensure the fair distribution of resources among regions. The government and educational institutions should make concerted efforts to enhance the public's perception of education and increase overall awareness regarding education.
Export of Chinese Animated Film:A Case Study on Nezha
Authors: Zhao Siyun
Published: July 2024

The box office of Chinese films is growing, and domestic films have made a great contribution.Chinese films has also becoming an important component of Chinese cultural exportation. Animated films have advantage of having wider audience, which can convey national values more gently and shape the national image imperceptibly. This paper took the animated film "Nezha", which was a dark horse at the domestic box office, as an example to analyze the advantages and disadvantages of Chinese animation film in cross-cultural communication. The study found that although technique and animation visual effects received good commonts from the overseas audience, the cultural barriers and the lack of commercial publicity was still a constaint for Chinese animated films.
From the Death of the Gracchi Brothers to the Downfall of the Republic
Authors: Yuan Ximan
Published: July 2024

This paper aims to trace the legacy of the Gracchi brothers and the effect of their reform throughout the republican era, specifically over how it foreshadows the collapse of the Republic. Although the reform implemented by the Gracchus brothers failed, it is still of great historical importance because it reveals the corrupted nature of Roman republic while taking the socioeconomic background into consideration to predict the downfall Rome. The downfall of the Gracchi brothers was primarily resulted from the majority of the senators whose interests were against the reform measures because the benefits for the majority were built on the lost of the senators. As a result, the Senate refused to accept changes of any sort and rejected an opening advancement proposed to improve the welfare of the People, leading to the tragedy of the death of Gracchi brothers.
The Curse of the Past: Manchukuo and the Han-Manchu Relationship
Authors: Li Chengxi
Published: July 2024

Historians have conducted extensive research on Japan after World War Two. This study analyzes the Japanese aggression in Manchuria and its rationales in creating a Greater East Asia Co-Prosperity Sphere. It explores the ways in which the establishment of Manchukuo shape the relations between Han and Manchu Chinese in contemporary China. The analysis is based on multifarious sources, including newspapers in the twentieth century that recorded the history of Manchukuo and findings by authoritative researchers on East Asia. This study sheds light on the status of the Manchu Chinese, who have almost been assimilated into the overwhelming Han majority.
Current materials used in artificial vascular tissue engineering
Authors: Wu Wantong
Published: July 2024

A commonly employed approach in the field of vascular tissue regeneration involves the utilization of artificial vascular tissue implants. These implants are designed to replicate the natural architecture of blood vessels through the use of artificial scaffolds, followed by cell growth induced onto these scaffolds, which are subsequently introduced into the body to replace damaged blood tissue. One of the primary obstacles encountered in implementing this technique pertains to the selection of materials that most nearly mimic the characteristics of naturally occurring tissue. Specifically, the aim is to develop an artificial device that closely emulates the biological functionality while eliciting minimal immunological reaction. A wide range of materials for constructing scaffolds has been extensively documented, encompassing natural, synthetic, and composite materials, as well as decellularized extracellular matrix. This study aims to conduct a comprehensive analysis of the existing literature in the field of vascular tissue engineering, utilizing methods of literature review and analysis. The examination will focus on evaluating the strengths, flaws, and availability of the available resources in this area of research.
The evolution and application of mechanical instruments in brain-computer interface technology
Authors: Mo Shihan
Published: July 2024

Brain-Computer Interfaces (BCIs) are innovative systems that facilitate direct communication between the human brain and external devices. Leveraging advances in neuroscience and engineering, BCIs can decode neural activity, allowing users to control computers, prosthetics, or even communicate thoughts without the need for peripheral motor activity. While primarily developed for assisting individuals with motor or communication disabilities, the potential applications span from gaming to advanced robotics. Despite rapid progress, challenges remain in achieving high-resolution decoding and ensuring long-term stability. As the field advances, ethical considerations about privacy, security, and human augmentation also emerge. This paper aims to provide an in-depth exploration of the field of BCI technology. The first part illustrates the remarkable evolution undergone by BCI, from electroencephalography (EEG) to functional magnetic resonance imaging (fMRI). The next part mainly describes the principle of BCI and the devices that are used for processing the interface. The following part highlights the challenge faced by BCI and how ethics and security should be deliberated.
Synthetic route of dasatinib and its application in leukemia
Authors: Liu Xindi
Published: July 2024

Over the years, drugs against cancer have received more and more attention, and dasatinib has become a very promising drug for the therapy of Chronic Myelogenous Leukemia (CML) and Acute Lymphoblastic Leukemia (ALL) due to its unique mechanism of action that has a significant impact on the treatment of leukemia. Although dasatinib has a manageable safety profile, adverse effects such as myelosuppression, fluid retention, and cardiovascular events have been reported; therefore, regular monitoring and dose adjustments are necessary to minimize these risks and to mitigate potential adverse effects. In addition, further studies are needed in the future to fully exploit the potential of dasatinib in the treatment of these hematologic malignancies. In this paper, two diseases that can be treated by Dasatinib are selected for elaboration, moreover, three emerging synthetic routes of Dasatinib are selected, and their advantages and disadvantages are compared in terms of cost, total yield, and environmental friendliness, on the basis of which, corresponding suggestions for improvement are made, and finally, an overview of the application status of this drug is given.
Current status of treatment and rehabilitation of lumbar disc herniation
Authors: Chen Lan , Deng Changjiang , Li Bingyan
Published: July 2024

Lumbar disc herniation (LDH) is now a widespread and common disease with a large number of patients. Chronic pain caused by LDH has now become an important problem affecting the broad masses of the people, causing a serious impact on the peoples daily life and economy, and even the production and economy of the society. In the treatment of chronic pain for LDH has a long history, in recent years also has many new treatment methods, but because of its complex pathogenesis, there is still few treatments, can achieve better effect in LDH chronic pain, makes it has become a worldwide problem. This paper will conduct the latest review of modern medicine and traditional Chinese medicine for the treatment of LDH chronic pain, in-depth research and explore the treatment of LDH chronic pain, in order to provide scientific research ideas and scientific basis for clinical treatment and research of this disease.
Роль цифровых технологий в сельском хозяйстве: анализ и оценка (на примере Армении)
Authors: Арутюнян Геворг Арамович
Published: July 2024

Технологический прогресс рассматривается как один из способов устойчивой интенсификации сельского хозяйства. Имея возможность использовать современные технологии на всех этапах производственного процесса и соответствующие компетенции, можно создать высокоэффективное производство. С другой стороны, игнорируя вопрос цифровой трансформации, невозможно выстоять конкурентную борьбу. Данная проблема существует как на уровне отдельного предприятия (хозяйства), так и государства, становясь угрозой для продовольственной безопасности. Анализу роли цифровых технологий в сельском хозяйстве и проблем их внедрения посвящены разные научные работы. Однако, по сведениям автора, на примере Армении нету оценок об уровне внедрения ИКТ в сельское хозяйство и анализа их влияния на доход хозяйства, чем и обусловлена актуальность темы. Տեխնոլոգիական առաջընթացը դիտվում է որպես գյուղատնտեսության կայուն ինտենսիվացման ուղիներից մեկը: Արտադրական գործընթացի բոլոր փուլերում ունենալով ժամանակակից տեխնոլոգիաներ կիրառելու հնարավորություն և համապատասխան իրավասություններ՝ հնարավոր է ստեղծել բարձր արդյունավետությամբ արտադրություն։ Մյուս կողմից, անտեսելով թվային փոխակերպման խնդիրը, անհնար է դիմակայել մրցակցությանը։ Այս խնդիրն առկա է ինչպես անհատ տնտեսության, այնպես էլ պետության մակարդակով՝ դառնալով պարենային անվտանգությանը սպառնացող գործոն։ Տարբեր գիտական աշխատանքներ նվիրված են գյուղատնտեսության մեջ թվային տեխնոլոգիաների դերի և դրանց ներդրման խնդիրների վերլուծությանը։ Սակայն, ըստ հեղինակի, Հայաստանի օրինակով չկան գյուղատնտեսությունում ՏՀՏ-ի ներդրման մակարդակի վերաբերյալ գնահատականներ և դրանց ազդեցության վերլուծությունը գյուղացիական տնտեսությունների եկամուտների վրա, ինչն էլ պայմանավորում է թեմայի արդիականությունը։
Technological progress is seen as one of the ways of sustainable intensification of agriculture. Having the opportunity to use modern technologies at all production stages and having the necessary skills and competence, it is possible to create highly efficient production. On the other hand, it is impossible to withstand the competition while ignoring the issue of digital transformation. This problem exists both at the individual (farm) level and at the state level, becoming a threat to food security. Various studies are devoted to the analysis of the role of digital technologies in agriculture and the problems of digital penetration in agriculture. However, according to the author, using the case of Armenia, there are no estimates of the level of implementation of ICT in agriculture and analysis of their impact on farm income, which provides the relevance of this study.
Դրամական հոսքերի կառավարման իրատեսական վերլուծությունը արտադրական կազմակերպություններում
Authors: Ներսիսյան Կարեն
Published: July 2024

Գլոբալ և տարածաշրջանային զարգացումների արդի անորոշությունների ու ռիսկերի պայմաններում խիստ կարևորվում են հատկապես ՀՀ իրական հատվածի կազմակերպությունների դրամական հոսքերի հաշվառման, վերլուծության, պլանավորման և վերահսկման տեսական դրույթների և գործնական գործիքների կատարելագործման հարցերը արտադրական կազմակերպությունների շուկայական արժեքը բարձր մակարդակի հասցնելու համար, ինչը հաստատում է ուսումնասիրության արդիականությունը:
В условиях нынешней неопределенности и рисков глобальных и региональных событий особенно важны вопросы совершенствования теоретических положений и практических инструментов учета, анализа, планирования и контроля денежных потоков организаций реального сектора РА с целью повышения рыночной стоимости производственных предприятий, чем и обуславливается актуальность исследования.
In the context of the current uncertainty and risks of global and regional events, the issues of improving the theoretical provisions and practical tools for accounting, analysis, planning and control of cash flows of organizations in the real sector of the Republic of Armenia are especially important in order to increase the market value of production, which determines the relevance of the study.
Գործարար միջավայրի զարգացման միտումները ՀՀ-ում. Համեմատական վերլուծություն
Authors: Խաչատուրյան Վարդուհի Արեգի , Շամխալովա Էլինա Սերգեյի
Published: July 2024

Բարենպաստ գործարար միջավայրի առկայությունն արդեն իսկ տնտեսության ամենակարևոր շարժիչ ուժերից մեկն է։ Ընդհանուր առմամբ, երկրի գործարար միջավայրը կախված է արտաքին ու ներքին միջավայրերի գործոններից, որի ազդեցությամբ գործում է բիզնեսը։ ՀՀ-ում գործարար միջավայրի կայունությունը, զարգացման մակարդակը, դրանում առկա հնարավորությունները և խոչընդոտները ուղղակի ու անուղղակի կերպով պայմանավորում են գործարարության ակտիվության և դյուրինության հնարավոր մակարդակը։ Ինչպես և մի շարք երկրներում ՀՀ տնտեսական և սոցիալական կայունության հիմնական երաշխիքը հանդիսանում է գործարար միջավայրը, որի զարգացումը հնարավորություն է ընձեռում մեղմելու տնտեսական և սոցիալական դժվարությունները, հետևաբար՝ գործարար միջավայրի զարգացումն ազդում է մեր երկրի կյանքի որակի բարձրացման վրա: Այս և նմանատիպ հիմնախնդիրների լուծումները արդիական են դարձնում հետազոտության թեման: Наличие благоприятной бизнес-среды уже является одной из важнейших движущих сил экономики. В целом бизнес-среда страны зависит от факторов внешней и внутренней среды, под влиянием которых функционирует бизнес. Стабильность, уровень развития бизнес-среды в Армении, существующие в ней возможности и препятствия прямо и косвенно обуславливают возможный уровень активности и легкости ведения бизнеса. Как и в ряде стран, основной гарантией экономической и социальной стабильности Армении является бизнес-среда, развитие которой дает возможность смягчить экономические и социальные трудности, следовательно, развитие бизнес-среды влияет на повышение качества жизни в нашей стране. Решения этих и похожих проблем и делают тему исследования актуальной. The presence of a favorable business environment is one of the most important driving forces of the economy. In general, the business environment of a country depends on the factors of the external and internal factors under the influence of which the business operates. Stability, the level of development of the business environment in Armenia, and the existing opportunities and obstacles directly and indirectly determine the possibilities and ease of doing business. As in many countries, the main guarantee of Armenia's economic and social stability is the business environment, the development of which enables it to mitigate economic and social difficulties, therefore, the development of the business environ-ment brings to the improvement of the quality of life in Armenia.
Technological features of common bean growing under climate changes in the Forest Steppe of Ukraine
Authors: Trush S.H. , Parfenіuk O.O.
Published: July 2024

Study of the influence of sowing dates and methods, planting density and genotype of the variety on the processes of forming the productivity of common beans under climatic changes in the Forest-Steppe of Ukraine. Methods. Field (experiments, phenological observations), laboratory (determine the protein content), measuring and weighing (to determine the crop structure), statistical (to process mathematically the achieved results). Results. The results of studies on the influence of elements of cultivation technology on the productivity potential of common beans under climatic changes in the Forest Steppe of Ukraine are presented. A significant influence of variety genotype and sowing methods on the yield and protein content of common bean grains during cultivation in this region was established. It has been proven that in the agro-climatic conditions of the Forest Steppe, the highest yield of common bean grain is observed in wide-row sowings of the first season with a planting density of 450 thousand pcs/ha. It was 3.51 t/ha in the Mavka variety, 3.29 t/ha in the Panna variety. Due to climatic changes in the Forest Steppe of Ukraine, wide-row sowing of common beans was characterized by a higher grain yield in the first, and ordinary row crops – in the second sowing period. The highest protein content in common bean grains (21.45% and 20.97%) in Mavka and Panna varieties was established at a planting density of 450 thousand pcs/ha in the first sowing period. Conclusions. A significant influence of sowing methods and terms, planting density and variety genotype on the productivity potential of common beans has been established. Wide-row sowing of common beans was characterized by a higher grain yield. The higher protein content in the grain was observed in all variants of the experiment during the first sowing period. The most productive option was the experiment of the first sowing period with a planting density of 450 thousand pcs/ha.
AVALIAÇÃO DE TESTE DE SCHIMER E TONOMETRIA OCULAR EM CÃES SUBMETIDOS A ANESTESIA DISSOCIATIVA PARA OVARIOHISTERECTOMIA E ORQUIECTOMIA ELETIVAS
Authors: Nogueira Mônica Capla , Friolani Milena , Cirota Rafaela
Published: July 2024

Com o objetivo de avaliar a produção de secreção lacrimal e a pressão intraocular de cães sob anestesia dissociativa para esterilização eletiva, foram realizados testes de Schirmer, com fita milimetrada específica e aferição da pressão intraocular, utilizando a técnica de tonometria de rebote. Para isso, 26 animais de diferentes raças, idades e sexo, foram examinados em dois diferentes momentos, sendo o primeiro momento imediatamente antes da sedação, no pré-operatório, seguido de outra mensuração, num segundo momento, após o procedimento cirúrgico (pós-operatório). Ao final do segundo momento de análise, somente 2 pacientes obtiveram valores satisfatórios (maior ou igual a 15mm/min) em ambos olhos no teste de Schirmer. Na técnica de tonometria de rebote, 3 pacientes apresentaram a PIO maior que 30mmHg e 7 menor que 15 mmHg, sendo esta diferença explicada pela associação de drogas anestésicas dissociativas. Tais alterações frente aos valores basais, revelam a importância da lubrificação ocular em pacientes anestesiados.
DEBT TO EQUITY RATIO AND SALES GROWTH OF LISTED OIL AND GAS COMPANIES IN NIGERIA
Authors: Balarabe Lawal, Amiru ,   Federal University Gusau, Faculty of Management and Social Sciences, Iliyasu Sama’ila ,   Federal University Gusau, Faculty of Management and Social Sciences
Published: July 2024

Background: The relationship between a company's financial structure is an area of extensive research in corporate finance. Aims: The general objective of this study is to investigate the effect of debt to equity ratio on the sales growth of listed oil and gas companies in Nigeria. Methods: The study covers a period of ten years from 2013 to 2022 using a population of twelve (12) oil and gas companies and a sample of eight (8) companies. Data for the study were obtained through secondary sources using annual financial reports of the listed companies on the Nigerian stock exchange for the period. Debt to equity ratio was the independent variable while sales growth served as the dependent variable. They were measured using Ordinary Least Squares Regression. Conclusions: Findings revealed that debt to equity ratio has a positive and significant effect on sales growth. It was concluded and recommended that companies in the Nigerian oil and gas sector strategically manage their Debt to Equity Ratio (DTER). Implications: This involves carefully balancing the benefits of leveraging through debt, such as interest tax shields, against potential financial distress costs.
Natural isothiocyanates of the genus Capparis as potential agonists of apoptosis and antitumor agents: Mechanisms and implications
Authors: Eid Nabil , Bhatnagar Payal
Published: July 2024

In this editorial, we comment on a recent publication, which highlights the important findings from the study, including the antitumor and anti-inflammatory effects of isothiocyanates, their underlying mechanisms, and implications. Additionally, a related perspective is discussed.
Bibliometric visualisation of student knowledge and skills in key literacy domains
Authors: Nwagwu Williams E.
Published: July 2024

This study utilised bibliometric visualisation of keywords used to represent documents on reading literacy, scientific literacy, and mathematical literacy indexed in the Scopus database to analyse the volume and growth of the literature. The study adopted a bibliometric research design, an approach that is also quantitative. Data was collected from Scopus, and analysis was based on Scopus' built analytical facility while mapping was carried out using VOSViewer. Reading literacy is the youngest of the three literacies, with early references dating back to 1607. However, research on reading literacy began to gain momentum in 2002. Mathematical literacy is the oldest, but significant growth occurred around 2003, while scientific literacy dates back to 1963. The trend in publications shows the highest growth for reading literacy and the lowest for mathematical literacy. Analysing document types revealed that scientific literacy had the largest quantity of documents, while reading literacy had a higher proportion of articles compared to the other two literacies. The study provides valuable insights into the historical development and current trends within these literacy domains, shedding light on their changing dynamics and challenges.
SHORTAGE OF PERSONNEL IN THE MODERN RUSSIAN LABOR MARKET: CAUSES, TRENDS, WAYS TO OVERCOME
Authors: Safonova Svetlana , Sheyhova Marina
Published: July 2024

The article is devoted to the study and analysis of the shortage of personnel in the labor market in recent years. Statistical data are presented by region, by gender type, and by professional structure.
The causes, consequences and factors of the labor market deficit that led to the labor crisis at the current stage of economic development are investigated. The dynamics of vacancies and resumes for 2021-2023 has been studied. The demographic pit of 1990-2000 and its impact on the current economy and personnel shortage are described.
The impact and risks of staff shortages on the Russian economy are considered. The factors influencing further changes in the market are investigated, as well as forecasts for the current year. The measures of state policy aimed at reducing the personnel deficit are presented.
EFFECTIVE ACTIVITY OF NON-PROFIT ORGANIZATIONS AS THE BASIS OF A SOCIALLY ORIENTED ECONOMIC DEVELOPMENT STRATEGY
Authors: Bunchikov Oleg , Mihnenko Tat'yana , Sedyh Yuliya
Published: July 2024

The article discusses issues related to the activities of legal entities of non-profit organizations (NPOs) in the Russian Federation. The dynamics of the number of NPOs in Russia as a whole has been studied. An analysis of the number of functioning NPOs among the federal districts of our country was carried out. The dynamics of the number of operating non-profit organizations in the Southern Federal District (SFD), as well as in the territories of the constituent entities of the Southern Federal District, has been studied. An analysis of the dynamics of the number of operating non-profit consumer cooperation enterprises (PCs) was carried out, both in the Russian Federation as a whole and among federal districts. The dynamics of PC indicators among the subjects of the Southern Federal District was studied. Conclusions are formulated and directions for further development of NPOs in the Russian Federation are determined.
Pendekatan dengan Oversampling dan Undersampling untuk Meningkatkan Akurasi Diagnostik Kanker Tiroid
Authors: Purnajaya Akhmad Rezki , Darmawan Justin , Yamin Valerian , Charles Charles
Published: July 2024

Kanker tiroid, yang menjadi perhatian global dan sering kali tidak memiliki gejala awal, sehingga memerlukan deteksi yang tepat. Penelitian ini menggunakan Support Vector Machine (SVM) untuk identifikasi subtype kanker tiroid, yang bertujuan untuk meningkatkan akurasi, sensitivitas, dan spesifisitas. Dengan memanfaatkan data klinis, penelitian ini menggabungkan pemrosesan awal data dan memanfaatkan Random Over-Sampling (ROS) dan Random Under-Sampling (RUS) untuk mengatasi ketidakseimbangan kelas. Hasilnya menunjukkan kinerja klasifikasi yang tinggi, dengan data sampel menunjukkan sensitivitas yang unggul. Penerapan SVM yang sukses, bersama dengan ROS dan RUS, menjanjikan akurasi diagnostik yang lebih baik dan hasil pasien yang lebih baik.
Tingkat Kebugaran Jasmani Pemain Futsal Di Desa Bailangu Timur Kecamatan Sekayu
Authors: Suhadi Setiawan  , Daryono Daryono  , Agung Mahendra
Published: July 2024

The aim of conducting this research is to determine the level of physical fitness of futsal players in East Bailangu village, Sekayu subdistrict. This research method uses a deductive quantitative method with a survey research design. Using a purposive sampling technique is a sampling technique from certain data sources. Samples are taken in age categories ranging from 18-22 years. The sample used was 15 people, who were futsal players in East Bailangu village. Based on the results of this research, the results of the research and discussion showed that the level of physical fitness of futsal players in East Bailangu village, Sekayu sub-district, was mostly in the very good category, 0%, in the good category, 20%, in the fair category, 46.66%, in the poor category. amounting to 33.33% and those in the less than 0% category. The results of this research can be concluded that the physical fitness of futsal players in East Bailangu village, Sekayu subdistrict is sufficient.
Penerapan Model Pembelajaran Inkuiri Terbimbing Untuk Meningkatkan Hasil Belajar IPA Materi Ekologi Dan Keanekaragaman Hayati Indonesia Siswa Kelas VII.5 SMP Negeri 35 Pekanbaru Tahun Ajaran 2023/2024
Authors: Yuni Ismaeti  , Ibnu Hajar
Published: July 2024

The purpose of this study was to improve the science learning outcomes of students in class VII.5 SMPN 35 Pekanbaru in the academic year 2023/2024 by applying the guided inquiry learning model which was carried out on February 28 to April 24, 2024 in class VII.5 SMP Negeri 35 Pekanbaru in the academic year 2023/2024 which amounted to 34 students with 17 male students and 17 female students. This research is a Classroom Action Research (CAR).  The parameters measured were student learning outcomes in the form of absorption and student learning completeness consisting of individual and classical completeness. Data analysis was carried out descriptively to determine the absorption of  (Cognitive) and (Psychomotor) values. The absorbency of students' scores before CAR 46.76% increased in cycle I to 47.32% and in cycle II increased again to 82.91%. Classical completeness of scores before CAR 0.00% in cycle I remained with 0.00% and increased in cycle II to 97.06%. The absorption rate of students' score before CAR was 54.11%, increased in cycle I to 75.22% and increased again to 86.35%. Classical completeness of students' scores before CAR 0.00% in cycle I increased to 85.29% and again increased to 94.12. It can be concluded that the application of the guided inquiry learning model can improve the science learning outcomes of students in class VII.5 SMP Negeri 35 Pekanbaru in the academic year 2023/2024..
Pengaruh Kedisiplinan Kerja dan Kompetensi Terhadap Kinerja Karyawan pada PT. Skinsol Kosmetik Industri Kabupaten Bandung Barat
Authors: Yudiyanto Joko Purnomo  , Riski Amalia Fadhilla
Published: July 2024

This research can be concluded as follows. The method used in this research is a quantitative method. The population in this study was 39 permanent employee respondents. This research uses the census method and uses a questionnaire for data collection. The results of validity and reliability tests using the Person product moment correlation method and Cronbach's alpha, it is known that the items created are valid and calculations show that work discipline partially has a significant positive effect on employee performance, while partial competence has a significant positive effect on employee performance. The results of calculating the value of the influence of work discipline and competence simultaneously by looking for the coefficient of determination show how much influence there is between the two variables which can be studied from the R value and is 0.742. The size of the R square (R2) is 0.551, so the coefficient of determination (KD) is 0.551 x 100% = 55.1%, this means that it shows the influence of work discipline and competence on employee performance by 55.1% while the remaining 44.9% is influenced by other variables.
Analisis Tingkat Kesehatan Bank Dengan Pendekatan Risk Profile, Good Corporate Governance, Earnings, And Capital Pada PT. BPR Bank Jombang Perseroda
Authors: Sabrina Sindy Aulia
Published: July 2024

This research is aimed at analyzing the level of bank health at PT BPR Bank Jombang Perseroda which was carried out using RGEC method. The data used comes from the financial reports of PT BPR Bank Jombang Perseroda for the 2018-2022 period or five years and 40 company data was found. The RGEC method was employed during the data analysis. Based on the conducted analysis, it was discovered that PT BPR Bank Jombang Perseroda had a fairly excellent rating from 2018 to 2022 (Composite rating 3).
Effect Bioameliorants and Interval of Ready-to-Absorb Nutrient Solution on Soil Health, Crop Productivity, and Quality of Chili Pepper Yields
Authors: Simamora Falensius Abram ,   Soil Science Study Program, Faculty of Agriculture, Universitas Padjadjaran, Zahra Alfira , Limbong Agatha Dita , Fauziah Nicky Oktav , Simarmata Tualar , Fitriatin Betty Natalie , Sudirja Rija , Fakhrurroja Hanif , Bangkit Harry , Turmuktini Tien ,   Soil Science Study Program, Faculty of Agriculture, Universitas Padjadjaran,   Soil Science Study Program, Faculty of Agriculture, Universitas Padjadjaran,   Soil Science Study Program, Faculty of Agriculture, Universitas Padjadjaran & Agricultural Development Polytechnic Yogyakarta Magelang,   Department Soil Science, Faculty of Agriculture, Universitas Padjadjaran,   Department Soil Science, Faculty of Agriculture, Universitas Padjadjaran,   Department Soil Science, Faculty of Agriculture, Universitas Padjadjaran,   National Research and Inovation Agency of Republic Indonesia,   National Research and Inovation Agency of Republic Indonesia,   Faculty of Agriculture, Universitas Winaya Mukti
Published: July 2024

Red chili peppers have high economic value due to increasing consumer demand, particularly in large cities, which require about 800,000 tons per year. Despite an increase in production from 1,360,571 tons in 2021 to 1,475,821 tons in 2022, productivity is hindered by reduced harvested area and soil degradation due to the excessive use of chemicals and inorganic fertilizers. This study aims to examine the interaction between bioameliorant application and intervals of ready-to-use nutrient solution on soil health, productivity, and the quality of chili yields, as well as to determine the optimal dosage. The study utilized a factorial Randomized Block Design (RBD) with two factors: bioameliorant dosage (0, 3, and 6 tons/ha) and ready-to-absorb nutrient solution application intervals (every 1, 3, and 5 days), with three replications. Observed responses included populations of PSB, Azotobacter, Azospirillum, total bacterial populations, organic carbon (C-Organic), pH, fruit number per plant, fruit weight per plant, and yield quality. The results indicated that the interaction between bioameliorant and ready-to-absorb nutrient solution intervals significantly affected C-Organic levels. Total bacterial populations were independently influenced by bioameliorant dosage and ready-to-absorb nutrient solution intervals, while fruit weight per plant and grade B yield quality were independently influenced by ready-to-absorb nutrient solution intervals. The highest C-Organic level was achieved with 6 tons/ha of bioameliorant and ready-to-absorb nutrient solution applied every day. The highest total bacterial population was obtained with 6 tons/ha of bioameliorant. The highest total bacterial population and fruit weight per plant were achieved with ready-to-absorb nutrient solution applied daily.
Biological Roles of Methionine and its Effect on Hatched Embryos and the Performance of Broiler: A Review Article
Authors: Majeed Nashwan ,   DNA Research Center/University of Babylon/, Babylon, Iraq
Published: July 2024

The development taking place in the growth of poultry birds has prompted researchers and specialists in the field of bird nutrition to search for solutions and food alternatives that are less expensive and with the same nutritional value to compensate the birds and balance their diets to meet the needs of mineral elements, vitamins and amino acids (protein). In view of the increasing demand for meat, this increase has been met with a steady increase. The use of manufactured feed additives and antibiotics had a negative impact on the growth of poultry, and some of them were deposited in the edible tissues of the bird. They were thus transmitted to the consumer, causing many diseases. Given the primary purpose of the additives, which is to balance all the elements involved in the composition of bird feed, I considered safe food additives such as liquid solutions and a group of vitamins, amino acids, and plant extracts, and since the primary return from most poultry projects is the economic return, the main goal was to focus on sources of amino acids as they are the basic unit for building protein, including the amino acid methionine as it is part of a group of amino acids called the determining factors in the composition of diets.