bluuebunny/crossref_metadata_2025 huggingface dataset:
Borik Asitin Anti-Proliferatif ve Anti-Apoptotik Etkilerinin İnsan Küçük Hücreli Dışı Akciğer Kanseri Hücrelerinde TGF-β Sinyal Yolağı Üzerinden İncelenmesi
Authors: SEMERCİ SEVİMLİ Tuğba , GHORBANİ Aynaz , SEVİMLİ Murat
Published: September 2023

Amaç: Akciğer kanseri, tüm dünyada hem kadın hem de erkeklerde en sık görülen kanser türüdür. Son yıllarda kanser konusunda elde edilen bilimsel gelişmelere rağmen, bu patoloji hala yüksek mortalite oranları ile ilk sıralarda yer almaktadır. Akciğer kanseri olgularının %85’ini küçük hücreli olmayan akciğer kanseri oluşturmaktadır. Bu hastalarda hastalığın seyri oldukça kötü ilerlemekte ve tanısı çoğunlukla ileri evrelerde konulduğundan, çoğu hastada uygulanan tedaviler başarılı olamamaktadır. Borik asit (BA) sahip olduğu kimyasal özellikler, düşük yan etki oranları ve anti-kanserojen etkilere sahip esansiyel bir mikro elementtir. Bu çalışma kapsamında anti-proliferatif ve anti-apoptotik etkileri bilinen BA’nın, küçük hücreli dışı akciğer kanseri hücreleri (A549) üzerindeki sitotoksik, anti-proliferatif ve apoptotik etkilerinin TGF-β sinyal yolağı üzerinden araştırılması amaçlanmıştır.
Yöntem: Çalışmada insan küçük hücreli dışı akciğer kanseri hücreleri (A549) kullanıldı. BA’nın sitotoksik analizi MTT analizi ile yapıldı. BA’nın apoptotik etkisi Annexin V/PI ve immünfloresan analizlerle belirlendi. TGF-β, SMAD2/3/4 genlerinin ekspresyon düzeyleri moleküler düzeyde kantitatif gerçek zamanlı polimeraz zincir reaksiyonu (RT-qPCR) ile analiz edildi. Her bir reaksiyon üç kez tekrarlandı.
Bulgular: MTT analizi sonucu 50 mM BA’nın A549 hücrelerinde proliferasyonu azalttığı gözlendi (p<0.01). 50 mM BA uygulaması ile 48. saatte apoptotik hücre oranı %9.7’ye, erken apoptoz evresindeki hücre oranı ise %10.1’e yükseldi. İmmünfloresan analizinde de A549 hücrelerinde Kaspaz-3 işaretlenme düzeyininin kontrol grubuna göre yüksek miktarda olduğu gözlendi. BA uygulanan A549 hücrelerinde SMAD3 ve SMAD4 genlerinin ifadesinde anlamlı bir değişme gözlenmedi. TGF-β geninin ifadesinde azalma gözlenirken (p<0.05), SMAD2 gen ifadesinde artış gözlendi (p<0.01).
Sonuç: Sonuçlar BA’nın; anti-proliferatif ve anti-apoptotik aktiviteye sahip yeni bir tedavi edici ajan olabileceğini göstermektedir. Ancak bu etkilere aracılık eden yolakların aydınlatılması için ileri düzeyde çalışmalara ihtiyaç bulunmaktadır.
Otizmli Çocuklarda Pilates Eğitiminin Fiziksel Performans ve Sosyal Becerilere Etkisi: Randomize Kontrollü Bir Çalışma
Authors: ÖZTÜRK Nazan , SÖYLER Ayşe Kübra , SAÇAN Selvinaz , ÜNVER Fatma , ADIBELLİ Derya , SEREL ARSLAN Selen
Published: September 2023

Amaç: Aerobik eğitim, çocukların fiziksel, bilişsel ve davranışsal işlevleri üzerindeki önemli faydaları nedeniyle otizmli çocuklar için önerilmektedir. Buna rağmen, otizmli çocuklarda pilates eğitiminin etkilerine ilişkin herhangi bir kanıt bulunmamaktadır. Bu çalışmada, otizmli çocuklarda pilates eğitiminin kas kuvveti, denge performansı, kaba motor beceriler ve sosyal beceriler üzerindeki etkilerinin karşılaştırılması amaçlandı.
Yöntem: Çalışmaya toplam 22 otizmli çocuk dahil edildi. Sonuç ölçütleri olarak maksimal izometrik kas kuvveti, denge performansı, kaba motor beceriler ve sosyal beceriler değerlendirildi.
Bulgular: Her iki eğitim grubunda da denge performansı ve kaba motor becerileri skorlarında iyileşme gözlenirken, sosyal beceri skorunda iyileşme gözlenmedi (p < 0,05). Kas gücünde sadece aerobik eğitim grubunda anlamlı bir iyileşme görüldü (p < 0,05). Gruplar arası karşılaştırmalarda, tüm sonuç ölçümlerinin hem aerobik eğitim hem de pilates eğitim grupları için istatistiksel olarak benzer olduğunu gösterdi (p > 0,05).
Sonuç: Bu çalışma, aerobik eğitim ve pilates eğitiminin her ikisinin de otizmli çocuklarda denge performansının ve kaba motor becerilerin geliştirilmesinde etkili olduğunu ve aerobik eğitimde kas gücünde daha fazla iyileşme olduğunu göstermektedir. Pilates eğitimi, otizmli çocuklarda denge performansını ve motor becerileri arttırdığı için alternatif bir eğitim olarak düşünülebilir.
The Degree of Commitment of School Principals to Professional Ethics from the Point of View of Secondary School Teachers and Students in the Directorate of Education of Bani Obaid District in Irbid Governorate
Authors: Al-Smadi Lina Abdul Karim , Al-Hiyari Hassan Ahmed
Published: September 2023

The study aimed to identify the degree of commitment of school principals to the ethics of the profession from the point of view of secondary school teachers and students in the Directorate of Education of the Bani Obaid District in Irbid Governorate. The study was based on the descriptive survey methodology. Two questionnaires were built to measure the degree of commitment of secondary school principals to professional ethics. The studsample consisted of (49) teachers and (379) female students. The results showed that the degree of commitment of school principals to the ethics of the profession from the teachers point of view was high.  The degree of commitment of school principals to the ethics of the profession from the students ’point of view was high.  The results revealed that there were statistically significant differences in the degree of commitment of school principals to the ethics of the profession from the point of view of (female and male students), in favor of female teachers.
Patterns of Leadership Behavior of Academic Leaders in the Universities of the Northern Territory and their Relationship to their Thinking Patterns According to the Integrated Thinking Model from the Viewpoint of Faculty Members
Authors: Moumni Maha Edrees , Jubran Ali Muhammad , Odeh Ahmed Suleiman
Published: September 2023

This study examined the leadership behaviors styles among academic leaders in universities at Nothern region and their relationship to thinking styles according to the integrated thinking model from the point of view of faculty members. This study adopted a correlational descriptive methodology. The sample of the study consisted of (345) faculty members selected using stratified random sampling. To achieve the objectives of the study, two instruments were employed after both validity and reliability were verified. These were Leadership Behavior Styles Scale and Hermann Thinking Styles Scale. The results of the study indicated that the dominant leadership style for academic leaders was the democratic style. The results also showed that the dominant thinking style according to the integrated thinking model was (B) thinking style which has attendancy to practice, order, and time management. There was a statistically significant positive correlation between democratic behavior style among academic leaders and all thinking styles according to the integrated thinking model.
The Degree of Effectiveness of the Educational Decision-Making Process among the Principals of Zarqa Kasbah Schools from the Teachers' Point of View
Authors: Al-Ma'aita Khitam Za'al Muhammad , Al-Harahsheh Mohammad Aboud
Published: September 2023

The study aimed at identifying the degree of effectiveness of the educational decision-making process of the principals of Zarqa Kasbah from the teachers' point of view. It, also, studied the effect of variables on the response of the sample of the study. The study used the descriptive survey methodology. The tool of the study consisted of (14) items, and the validity and reliability of the tool was confirmed. The study was applied on a sample of (375) male and female teachers, who were chosen by a simple random method. The study proved the following results: the degree of effectiveness of educational decision-making process of the principals of Zarqa Kasbah education school from the teachers’ point of view, was medium. The results indicated that there were statistically significant differences at the level (0.05>a) in the mean. Responses of the study sample subjects about the effectiveness of the educational decision-making process of the school principals of Zarqa Kasbah education schools, from the teachers 'viewpoint. These differences were due to the variables of gender and academic qualification. Moreover, it indicated that there were no statistically significant differences due to the variables of years of experience and specialization. In light of the proved results, the study recommended a set of recommendations, the most important of which are: increasing the participation of teachers in the school decision­ making process, in the way that reflected in the raising the effectiveness of educational decisions.
Predictive Maintenance in Rotating Machinery Using Deep Learning Techniques
Authors: Azim Mohd , Afzal Mohammad , Ariz Mohd , Samad Abdul
Published: September 2023

The integration of Artificial Intelligence (AI) in mechanical systems has revolutionized the way we perceive maintenance and failure detection. This research paper introduces a novel methodology to predict and assess machinery failures in rotating equipment, such as turbines and motors, using Deep Learning techniques while traditional methods often rely on rule-based algorithms and basic statistical models, our approach leverages Convolutional Neural Networks (CNN) to process vibration and acoustic signals, and Long Short-Term Memory networks (LSTM) to analyze time-series data. By assimilating these techniques, we aim to achieve early and accurate failure prediction. A dataset consisting of 10,000 hours of machinery operation was collected from an industrial partner. Features like vibration amplitude, operating temperature, and acoustic signatures were captured in varying operational conditions. Data augmentation techniques were also employed to amplify rare but crucial failure signatures. Our model achieved a prediction accuracy of 98.5%, outperforming traditional methods by 15%. Furthermore, the implemented model showed high robustness against noisy data, indicating its potential for real-world applications. This research not only presents a powerful tool for mechanical engineers but also underscores the immense potential of integrating AI in traditionally non-digital domains. The methodology can be expanded to other mechanical systems, paving the way for a new era of predictive maintenance.
Robot for Deploying First Aid Kit During Natural Disasters
Authors: H M Gayitri , R Ranjitha , S N Saniha
Published: September 2023

The development of a first aid kit deploying a robot for disaster response presents a significant advancement in improving emergency medical assistance during natural disasters. This project focuses on designing a robot controlled through a transmitter-receiver system, equipped with weather sensors, a Pi camera for live streaming, and autonomous deployment capabilities. The objective is to enhance the efficiency, safety, and reach of emergency response efforts in challenging environments. The integration of weather sensors enables the robot to assess and adapt to changing weather conditions, ensuring optimal safety during deployment. Real-time weather data guides the robot's decision-making, allowing it to avoid hazardous situations and respond effectively to dynamic environmental challenges. The Pi camera's live streaming feature provides remote visual information, enabling operators and emergency responders to monitor the robot's activities time. This real-time streaming enhances coordination, facilitates informed decision-making, and optimizes resource allocation, even from a remote location. The autonomous deployment of first aid kits is a crucial aspect of the project. The robot navigates through inaccessible or hazardous areas, ensuring the timely delivery of medical supplies to victims. This capability significantly reduces response times, mitigates risks faced by human responders, and increases the chances of survival and recovery for affected individuals.
Formulation and Evaluation of Colon Targeted Ciprofloxacin Microspheres
Authors: Srilatha Ch. , kulkarni T Giriraj
Published: September 2023

In the present study, Colon-targeted Ciprofloxacin hydrochloride microspheres were formulated and their in vitro properties were assessed to determine whether or not the antibiotic could be delivered to the colon. By utilizing span-80 as an emulsifying agent, ciprofloxacin hydrochloride microspheres for colon targeting were prepared using the emulsion-solvent evaporation method. According to the preliminary trial findings, the ratio of drug to polymer had an impact on the microspheres' properties. The Ciprofloxacin: Eudragit S-100+HPMC 6cps ratio of 1:1, 1:2, 1:3, 1:4, 1:5, and 1:6 were used to make the colon targeting microspheres, in which the ratio of Eudragit S-100 to HPMC was always 1:1. The combination of Eudragit S-100 and HPMC demonstrated increased release lag time and regulated release rate, which improved protection of the drug-containing core. For the majority of the formulations examined, zero-order release followed a time delay caused by the hydrogel's swelling/retarding behaviour before the medication started to come out of the microspheres. The colon-targeting microspheres were also tested for micrometrics, particle size and surface properties, percentage drug content, encapsulation effectiveness, and in vitro drug release study in the three different pH environments (0.1 N HCL, Phosphate buffer pH 6.8 and Phosphate buffer pH 7.4) for 12 hours. The kinetics of drug release in vitro and the drug release mechanism of the microspheres were further investigated. With a particle size of 58.9 m, an almost spherical shape, and free-flowing characteristics, the best formulation batch had the highest drug entrapment efficiency of 86.81%. It was followed by a zero-order rate release with a non-fiction-diffusion mechanism, which had an 82.77% drug release rate.
Application of the Empirical Mode Decomposition Method to Noise Reduction Using Seismic Event Data Recorded at Kirkuk Seismological Station.
Authors: Mahmmoud Zainab , Al-Rahim Ali
Published: September 2023

This study aims to use the Empirical Mode Decomposition for reducing the noise of passive seismic signals recorded across seismic event recorded at Kirkuk station which is one of the Iraqi Meteorological Organization and Seismology data, where human activities in Iraq's populous cities significantly impact the seismic recordings at Iraqi Meteorological Organization and Seismology stations sites. In this paper, we present an algorithm based on the Empirical Mode Decomposition. It is a data driven method used as a propelling tool for analyzing and decomposing non-stationary and non-linear data without any previous assumptions. Empirical Mode Decomposition generates a finite and often small number of Intrinsic Mode Functions. The decomposition is based on the direct extraction of the energy related to various intrinsic time scales, an important parameter of the system. Empirical Mode Decomposition technique is applied to the available seismic records to reduce the noise level in the records, which helps in the interpretation of the records.
Mapping of the Vulnerability to Water Contamination of the Kharroub River Dam (Northern Morocco) by Application of the SW Method
Authors: Touiss Youssef , Draoui Mohamed , Bouchnan Rachid
Published: September 2023

Pollution and contamination pose a permanent risk of limiting water resources. Urbanization and economic development contribute to the degradation of water quality. The preservation of this natural resource is a major necessity, especially in arid and semi-arid areas where surface water is very scarce. This work constitutes part of this environmental concern. It aims at mapping the vulnerability to contamination of the surface water of the Kharroub River dam (Morocco) and protecting its water resources. The method applied is the SW (Surface Water) method, which consists in elaborating thematic maps of three parameters: the hydric functioning of soils, the density of the hydrographic network and the importance of agricultural drainage. The realization and superposition of these maps allowed us to obtain the vulnerability map to surface water contamination of the Kharroub river watershed. The results obtained show that the low and medium vulnerability classes, representing 41.91% and 32.49% respectively, occupy most of the study area and are distributed throughout the basin. The areas presenting a high and a very high degree of vulnerability occupy respectively 24.65% and 0.95% of the surface of the watershed; they are located principally in the northern and the southern parts of the basin.
Stratigraphic Sequence and Diagenetic Effects of the Upper Qamchuqa Formation in Khabaz and Kirkuk Oil Fields, Northern Iraq
Authors: Abbas Mohammed
Published: September 2023

The Upper Qamchuqa Formation was deposited in Zagros foreland basin in the north of Iraq during the Late Albian age. Two boreholes from Kirkuk oil field (K-229) and Khabaz oil field (Kz-4) are selected in the current study, where 100 samples of cores and cutting were used to determine diagenetic evolution of the Upper Qamchuqa Formation. Five major sub-environments can be diagnosed within the Upper Qamchuqa sequence, they are: shallow-open marine environment, semi-restricted marine environment, restricted marine environment, shoal and deep outer ramp environment. The diagenesis process are contain the physical or chemical variations in sedimentary rocks and sediments that happen after the deposition, where many diagenetic process effect on the Upper Qamchuqa Formation which are: Micritization, Cementation with three types (blocky, drusy,and syntaxial calcite overgrowth cement ), Dolomitization with three types too (scattered, Pervasive coarsely ,and saddle dolomite), neomorphism, recrystallization, silicification, dissolution and compaction (mechanical and chemical). There are four sedimentary cycles: cycle A extends from the upper part of the underlying Upper Sarmord Formation (TST) to the shallow open marine facies (HST) of the lower part of Lower Qamchuqa in k-229 which ended with shoal facies, cycle B on the other hand, shows a grain dominated facies where the carbonates buildup kept pace with the still relative sea level (keep up) during high stand which deposited under semi-restricted and restricted successively, cycle C shows a marked variation in thickness within the sections (K-229 and Kz-4); it is greatest thickness was noticed at k-229 where its lower part is mostly mud dominated in Kz-4, and cycle D shows a distinct variation in facies change from grain-rich to mud-poor lithology of restricted to semi-restricted facies in the East (k-229) to predominantly restricted marine conditions at the central area (Kz-4).
Using One-Dimensional Geomechanical Model for Determining the Safe Wellbore Orientation of Zubair Reservoir, Southern Iraq
Authors: Alshibli Fadhil , Alhaleem Ayad
Published: September 2023

The wellbore instability issues are firmly occurring in the Iraqi oilfield and particularly in the southern region of Iraq. It is causing a significant loss of time dealing with many types of downhole problems, as well as an increase in the operations costs because of the instability consequences. By using the well information and open-hole logging data, the One-Dimensional (1-D) geomechanical model generated with Schlumberger Techlog software (V.2015) was used to assess the mechanical stability of the wellbore. The model was calibrated and validated by using core data (Triaxial test), the formation pore pressures, and the Mini-frac test). The 1-D model was validated across the actual well conditions (i.e., the original mud weight and the actual wellbore failure) by using three criteria of failures which are Modified Lade, Mogi-Coulomb, and Mohr-Coulomb. The validation process showed that the failure criterion of Mogi-Coulomb is better than the other two criteria in presenting the actual borehole failure, and thus it can be used to develop the plans of wellbore orientation. By investigating wellbore orientation with various scenarios, ranging from a vertical trajectory to the horizontal strategy, the wellbore orientation is mainly safe (with the minimum breakout) in vertical and inclined wells up to 40º with minimum mud weight of 11.7 and 12.6 ppg. The optimum wellbore trajectory should be in the direction of minimum horizontal stress, which is North-West to South-East (130º-160º). The developed plans provide a guideline for performing stable drilling operations in the south of Iraq and the nearby areas, thus effectively contributing in reduction the overall cost.
Rapid ascent: to the 75th anniversary of the artist Zinaida Kurchatova (1948–1983)
Authors: Габышева А.Л.
Published: September 2023

Статья посвящена творчеству якутского живописца Зинаиды Курчатовой. Цель работы — изучение творчества, выявление особенностей пластического и образного языка художника, работавшего в таких жанрах, как портрет, пейзаж, тематическая картина. С помощью искусствоведческого анализа были установлены композиционные и колористические приемы, трактовка образов автором. Особое внимание уделено пейзажу: колоритный, лаконичный, наполненный эмоциональной глубиной, лирико-эпичным содержанием, он повествует о красоте северной земли и открывает мировидение автора. Обзор выполнен на основе монографической коллекции З.К. Курчатовой, хранящейся в собрании Национального художественного музея Республики Саха (Якутия). Данная статья приоткрывает практически забытую страницу о творчестве члена Регионального отделения Союза художников Якутии, Союза художников России Зинаиды Курчатовой. Работа впервые публикует и вводит ее наследие в научный оборот. Материал актуален для осмысления творчества живописца и для представления более полной панорамы якутского изобразительного искусства второй половины ХХ века.

The article discusses the work of Yakut painter Zinaida Kurchatova. There was no specific focus on studying her legacy in art criticism. The goal of this article is to study the painter's works, to identify the features of her plastic and figurative language considering all the different genres she worked in, such as portrait, landscape, and themed based painting. The study was carried out in accordance with art review principles, which helped to identify compositional and coloristic techniques of the author, as well as her interpretation of images. Particular attention was paid to landscapes. Colorful, concise, full of emotional depth and lyrical-epic content, they recount the beauty of the Northern Land and open up the author's worldview. The study was based on the monographic collection of Zinaida Kurchatova, stored in the collections of the National Arts Museum of the Sakha Republic (Yakutia). This article reveals an almost forgotten page in the creative work member of the Artists Union of Yakutia, Regional Branch of the Union of Artists of Russia, of Zinaida Kurchatova. This is the first work to publish and introduce her legacy into scholarly discourse. The article is relevant for understanding the painter's work and presenting a more complete picture of Yakut fine arts of the second half of the 20th century.
13th Regional art exhibition “Far East”: numbers, facts, conclusions
Authors: Левданская Н.А.
Published: September 2023

Снижение качества региональных выставок последних лет не раз отмечалось исследователями, занимающимися современным отечественным искусством, и самими художниками. С помощью эмпирического количественного метода автором проведен анализ ротации художников Дальнего Востока, принимавших участие в XII и XIII Региональных выставках «Дальний Восток», выявлены видовые предпочтения в искусстве мастеров разных территорий региона. Методы наблюдения, сравнения, анализа экспозиции, каталогов зональных/региональных экспозиций разных лет позволили сделать выводы о некоторых причинах организационного порядка, ведущих в конечном счете к снижению качества проведения выставок, являющихся на протяжении около шестидесяти лет основным критерием состояния изобразительного искусства в регионах страны.

Researchers involved in contemporary Russian art and artists themselves have repeatedly noted the decline in the quality of interregional exhibitions in recent years. The author of the article, using an empirical quantitative method, analysed the rotation of artists of the Far East who took part in the 12th and 13th Regional exhibitions “Far East”, and identified the specific preferences in the art of masters from different territories. Methods of observation, comparison, analysis of exhibitions, catalogs of zonal/regional exhibitions of different years allowed the author to draw conclusions about some of the reasons for the organizational order, ultimately leading to a decrease in the quality of exhibitions, which for about sixty years have been the main criterion for the state of fine art in the regions of the country.
On the Generalization of Fractional Kinetic Equation Comprising Incomplete H-Function
Authors:   Dept. of HEAS (Mathematics), Rajasthan Technical University, India, JANGID KAMLESH , PUROHIT S.D. ,   Dept. of HEAS (Mathematics), Rajasthan Technical University, India, AGARWAL RITU ,   Dept. of Mathematics, Malaviya National Institute of Technology, India, AGARWAL RAVI P. ,   Department of Mathematics, Texas A&M University-Kingsville, USA
Published: September 2023

In the present work, a novel and even more generalized fractional kinetic equation has been formulated in terms of polynomial weighted incomplete H-function, incomplete Fox-Wright function and incomplete generalized hypergeometric function, considering the importance of the fractional kinetic equations arising in the various science and engineering problems. All the derived ﬁndings are of natural type and can produce a variety of fractional kinetic equations and their solutions.
Strategi Komunikasi Pemasaran Membangun Minat Pengunjung Synchronize Fest 2023
Authors: Sinaga Stevent Yulius , Nindi Iren Ayu
Published: September 2023

Studi "Strategi Komunikasi Pemasaran Membangun Minat Pengunjung Synchronize Fest 2023" diteliti. Dalam kasus ini, peneliti menemukan masalah di mana penyelenggara mengubah cara mereka berinteraksi dengan audiens karena festival besar dalam industri hiburan sangat bersaing dan berdampak pada pandemi global. Penyelenggaraan festival menghadapi sejumlah masalah. Ini termasuk kekhawatiran tentang kesehatan pengunjung, persaingan dengan festival lain, dan perubahan kebiasaan konsumsi hiburan. Oleh karena itu, rencana harus mencakup komunikasi kesehatan yang ketat, penekanan pada aspek festival unik , penggunaan media sosial dan teknologi, dan kolaborasi dengan influencer untuk menarik pengunjung.  Metode ini dapat membuat Synchronize Fest 2023 menjadi pengalaman yang tidak dapat terlupakan bagi semua oranghadir. Metode penelitian ini mengadopsi pendekatan deskriptif kualitatif dengan menggunakan model AISAS. Tujuan penelitian ini yaitu dapat mengetahui strategi komunikasi yang digunakan pada pemasaran untuk membangun minat pengunjung synchronize fest 2023 Hasil dari penelitiannya adalah Strategi komunikasi pemasaran digital yang diterapkan oleh @synchronizefest menggunakan teori AISAS (Attention, Interest, Search, Action, Share) telah terbukti sangat efektif dalam mempromosikan Synchronize Fest 2023 di platform Instagram.
Designing Risk Management Ramework on Fundamental, Technical Variables of Normal Period and Crisis With Stock Return
Authors: Saad Nurchairul Akbar
Published: September 2023

In the past two years, the global and Indonesian economies have been severely impacted by the COVID-19 pandemic, leading to below-target and negative growth rates worldwide. Indonesia declared the pandemic in March 2020, resulting in disruptions and lower-than-expected economic growth, with the first quarter of 2020 recording 2.97% growth compared to a consensus of 3.5-4.0%. Key sectors like manufacturing, retail, construction, and mining contracted, while household consumption dropped to 2.84% from 5.01% the previous year. This summary presents inflation and economic growth data in Indonesia as of October 2020 from the Central Statistics Agency. The research outcomes serve as reference material for government policy-making during crises, offer insights to infrastructure issuers in the capital market, assist investors in stock transactions and projections, and provide general knowledge about Indonesia's capital market.
LIGHT TRIAD PERSONALITY TRAITS AND COPING STRATEGIES IN TEACHERS
Authors: Bălan Alina Sanda , Ionescu Maria Claudia , Stan Andreea
Published: September 2023

Studies show that work-related stress among teachers is high. Job satisfaction and interactions with students are influenced by teachers’ coping skills with stressful situations and differences in response to stressful events can be explained by personality traits. The present study uses the Light Triad model of personality to examine whether prosocial traits such as empathy, compassion and altruism are associated with cognitive-emotional coping strategies in teachers. The prosocial orientation was measured using the Light Triad Scale (Johnson, 2018) and The Cognitive-Emotional Regulation Questionnaire (Garnefski et al., 2007) was used to identify teachers’ cognitive-emotional coping strategies, in relation to negative events or situations. The participants in this study included 120 Romanian teachers from different levels of preuniversitary education. The results revealed that empathy and altruism have small negative correlations with catastrophizing; all three prosocial traits are associated with the positive reappraisal, empathy positively correlates with accepting negative events and refocusing on planning and altruism positively correlates with accepting negative events and putting into perspective. We also found a positive correlation between empathy and rumination. Our findings extend the current understanding of the relationship between teachers’ prosocial personality traits and the coping strategies they use following negative life events.
PLANT PROTECTION METHODS IN ORGANIC FARMING
Authors: Bulut Sancar , Arslan Mahmet
Published: September 2023

Today, producers generally aim to increase product quality and diversify, but ultimately increase efficiency. On the other hand, when the negative effects of chemical pollution in nature is in consideration, the producer can’t harvest all of the produced crops, but they harvest the crops that aren’t consumed by diseases and pests. The increasing human movement and trade in the world in the last few hundred years has facilitated the transfer of harmful organisms from one geographical region to another. It is estimated that there are about 20 thousands potentially harmful organisms on the globe today. However, 5 thousands of these are known to be harmful to plants. In Turkey, 6 hundreds of these organisms cause economic damage. However, in 2011, according to the records of the Department of Phytosanitary and Quarantine in the General Directorate of Food and Control (GKGM), it was determined that there were around 470 harmful organisms in Turkey, and 350 of them had technical instructions and were combated. In other words, the number of harmful organisms that threat plant health is generally increasing. Even before there was no Ministry of Agriculture in Turkey, the fight against phylloxera started and the legislation and physical infrastructures were established due to the obligation to fight against pests. However, the last 100 years of pest control studies in plant production have revealed that the fight against harmful organisms is not sustainable when only chemical control measures are taken. Because faulty or excessive chemical applications sometimes cause irreversible damages to the ecosystems, cultivation areas, water sources, human health and food chains. For this reason, it is needed to include alternative control measures, such as biotechnical and biological controls, perhaps even more so, methods such as genetic control.
Factors Related to Hearing Threshold of Workers at PT. X
Authors: Putri Salsabila Liandra , Afianah Nuzula
Published: September 2023

Physical hazards are one of the several types of dangers in Occupational Health and Safety. Companies or industries that use machines in their work processes have the potential to cause a physical hazard. One of the physical hazards is noise. Noise exposure can have an impact on employee health, namely hearing loss. A decrease in hearing threshold values can cause communication disorders and concentration problems. Variables of sound intensity, period of work, age, and disease history can influence the reduction in hearing threshold values. The results of a preliminary study on workers at PT. X indicates the sound intensity is above the threshold value, namely 86dB and 16.6% of workers experience hearing loss. The aim of this research is to determine the factors related to the hearing threshold values of workers at PT. X. The methodology in this research uses a cross-sectional approach. This study had 30 workers as samples using total sampling techniques. The results showed that the sound intensity factors (ρ = 0.030) and disease history (ρ = 0.013) were related to the hearing threshold value. Meanwhile, the factors of work experience (ρ = 0.704) and age (ρ = 1.000) are not related to the hearing threshold value. The conclusion of this research is that there is a relationship between sound intensity and history of illness with the hearing threshold value of workers at PT. X.
Introduction to Vaginal Microbiota and its Relevance in Gynecological Health
Authors:   Escuela de Medicina, Instituto Politecnico Nacional, Vespero Fernando Hernandez , Alvarez Alcala Edgar Josue ,   Universidad Autónoma de Guadalajara, Fernández Danielle López ,   Universidad Autónoma de Baja California, Lopez Esparza Vicente Adrian ,   Universidad Autónoma de Guadalajara, Almeida Návar Alejandro Rafael ,   Universidad Autónoma de Baja California
Published: September 2023

This article provides an introductory exploration into the vaginal microbiota and its significance in maintaining gynecological health. The vaginal microbiota plays a crucial role in sustaining a balanced and harmonious vaginal ecosystem, influencing various aspects of reproductive well-being. By examining the composition and dynamics of the vaginal microbiota, this article highlights its impact on preventing dysbiosis and associated infections. A deeper understanding of the intricate interactions within the vaginal microbiota can pave the way for targeted therapeutic interventions aimed at promoting and preserving gynecological health.
The Role of Managerial Ownership as an Intervening Variable in the Relationship between Capital Structure, Asset Size and Profitability on Firm Value in Technology Companies of Indonesia
Authors:   Faculty of Economy and Business, Tanjungpura University, PONTIANAK., Yovani Catherine , Saleh Mustaruddin ,   Faculty of Economy and Business, Tanjungpura University, PONTIANAK.
Published: September 2023

This study aims to examine the effect of Capital Structure, Firm Size, and Profitability on Firm Value with Managerial Ownership as intervening variables. The population in this study embraces 45 companies belonging to the technology, heavy construction, and civil engineering companies respectively for the period of 2015-2021. All data used is panel data retrieved from Indonesia Stock Exchange (IDX) website. Using the purposive sampling method, the final sample becomes 15 companies or 105 year-firm. Employing the path analysis, this study found that capital structure and profitability had a significant positive effect on managerial ownership, while firm size had a positive and insignificant effect on managerial ownership. Capital structure and profitability have a significant positive effect on firm value, while managerial ownership has a positive effect on firm value but is insignificant. In addition, firm size has a negative and significant effect on firm value. Finally, managerial ownership cannot mediate the relationship between independent variables of capital structure, firm size, and profitability on firm value.
Human Development Index: Examining the Effect of Fiscal Decentralization and the Moderating Role of Private Investment
Authors:   Faculty of Economics and Business, Warmadewa University, Indonesia, Aditya Pramartha I Made , Adi Putra Gede Sanjaya ,   Faculty of Economics and Business, Warmadewa University, Indonesia, Putra I Komang ,   Faculty of Economics and Business, Warmadewa University, Indonesia
Published: September 2023

Bali Province is a tourist destination and has rapid economic growth in Indonesia, but Bali Province faces several challenges in terms of the Human Development Index (HDI). The achievement of HDI is the responsibility of local governments, especially in autonomous regions. With regional autonomy, the government has the flexibility to increase the degree of fiscal decentralization and design appropriate budget allocations. Bali Province is also one of the investment destinations for investors which certainly has an impact on people's lives. This research will try to examine the effect of the level of fiscal decentralization of a region on the achievement of the Human Development Index. This research also tries to use the role of private investment as a moderator. The research data comes from the financial statements and publications of the Central Bureau of Statistics of Bali Province for the period 2012-2021. The results of data testing show that fiscal decentralization has a positive and significant effect on HDI. Private investment has not been able to moderate the relationship between fiscal decentralization and HDI. When a region has a high level of financial independence, of course, the local government can more freely determine regional spending policies, especially to sectors that can increase HDI. In addition, local governments also need to pay attention to investments made by the private sector, so that they are in line with the government's objectives in increasing HDI.
KEEFEKTIFAN KONSELING KELOMPOK SFBC MENINGKATKAN SELF EFFICACY SISWA SMP NEGERI 19 PONTIANAK
Authors: Summiyati Mahza , Asrori Muhammad , Putri Amallia
Published: September 2023

The primary objective of this study is to examine the efficiency of Solution Focused Brief therapy (SFBC) group therapy as a means of enhancing the self-efficacy levels among seventh-grade students at SMP N 19 Pontianak. The chosen research methodology was experimentation, specifically employing a pre-experimental design research approach with a pre-test-post-test one group design. The participants in this study were selected using a purposive sampling technique. Specifically, a sample of 10 individuals with poor self-efficacy was drawn from a population of 31 individuals. Based on the computed data, the mean score of the pre-test (before to receiving any intervention) was 96 within the low category, while the post-test (after the administration of treatment) had an average score of 136 within the high group. The T statistic was derived using the Paired sample T-test, yielding a result of -3.928, accompanied by a significance level (Sig value). The p-value of 0.03, calculated using a two-tailed test, is less than the significance level of 0.05. This indicates that the alternative hypothesis (Ha) is accepted, while the null hypothesis (Ho) is rejected. Therefore, there is a significant difference in student self-efficacy before and after receiving SFBC group counseling treatment. Based on the findings, it can be inferred that SFBC group counseling demonstrates efficacy in enhancing the self-efficacy levels of seventh-grade students enrolled at SMP N 19 Pontianak.
Mathematical Modeling of Alcohol-Drug Concentration in the Bloodstream
Authors:   Department of Mathematics and Statistics, Federal University Otuoke, Nigeria, Bunonyo KW
Published: September 2023

This research involved the formulation of a system of mathematical models mimicking alcohol concentration in the human body and in the bloodstream, which are subjected to some initial conditions. The formulation starts with the an ideal presentation of the compartment diagram in Figure 1, the figure clearly indicates the two compartment in focus and the diffusion of alcohol from one compartment to the other with different rates including the elimination rate through urination and sweating that were not considered in this research. The aim of the research is to investigate the importance of the various rate constants on the alcohol concentration in the bloodstream, as well as investigating the drug dosage and volume of alcohol concentration impact in the bloodstream. The Laplace method (LM) was adopted to solve the model which represents, firstly, the alcohol concentration in the body where an exact solution was obtained, secondly, the exact solution was also obtained for the model depicting the alcohol concentration in the bloodstream with all pertinent parameters clearly spelt out. Lastly, numerical simulation was carried out using Wolfram Mathematica, version 12, where the pertinent parameters values were varied and the results presented graphically. The graphical results indicate that the various rate constants, dosage increase and the volumetric increase have impact and showed a corresponding effect on the drug concentration in the bloodstream. The novelty of this research is the fact that we’ve been able to mimic a real-life scenario, an alcohol concentration in the bloodstream, mathematically, and solved the system using Laplace methods and performed numerical simulation to show the importance of the pertinent parameters. This system can be recommended for scientists and engineers alike who could be interested in pharmacokinetics and Pharmacodynamics research.
Evaluation of the Immune Response by TNFα During Cervico-Uterine HPV Infection in Congo
Authors:   Faculty of Health Sciences, Marien Ngouabi University, Brazzaville, Republic of the Congo, Tsimba Lemba Paola Candyse , Anicet Boumba Luc Magloire ,   Pointe-Noire Research Zone, National Institute for Research in Health Sciences (IRSSA)
Published: September 2023

Introduction: The anti-tumour cytokine TNFα is involved in signalling apoptosis of infected cells. The aim of this study was to evaluate the immune response mediated by TNFα during HPV infection in women with precancerous and cancerous lesions of the uterine cervix in a Congolese population. Method: A total of 181 women underwent cervico-vaginal sampling for cervico-vaginal smears and HPV testing. A blood sample on EDTA tube was also taken to measure plasma TNFα concentrations. Papanicolaoum staining was used for the cervicovaginal smear. HPV testing was performed by real-time PCR on the CFX 96 automated system using the Anyplex II HPV28 kit (Seegene).Third-generation enzyme-linked immunosorbent assay (ELISA) was used to etermine plasma TNFα concentrations using the “Elisa TNFα Pars Biochem” Kit (Nanjing Pars Biochem Co., LTD China) according to the manufacturer’s instructions. Results: The mean age of the women was 39.8 ± 12.7 years, with a raté of 22.7% of anormal cytologies. The prévalence of HPV was 66.2%. TNFα Levels in patients with précancéreuse and cancers lésions ère signifiant hier thane in women with normal cytologie (p<0.0001). Mean TNFα concentrations ère 76.1ng/l for HPV-positive and 35.9 nm/l for HPV-négative (p<0.0001). TNFα concentrations ère élevâtes in sujets with high-ris HPV génotypes (82.6ng/l) compare with loris génotypes (72.6ng/l). Conclusion: Our résulte shoge élevâtes plasma TNFα Levels in patients with précancéreuse and cancers cervical lésions. This élévation was alto corrélâtes with oncogénique HPV génotypes.
The Use of Instagram in Impulsive Fashion Purchases amongst Kazakhstani Centennials
Authors: Satybaldiyeva Dinara , Kazhmuratova Aigerim , Kakitayeva Zhazira , Tymbayeva Zhazira , Tam Leona
Published: September 2023

The proliferation of digital technologies has made a huge impact on the development of consumers' behavior and purchasing habits. If to consider the rising presence and the role of centennials in the market, it is highly important to comprehend their preferences and consuming behavior. The primary purpose of this article is to examine the increasing role and impact of Instagram on the impulsive purchase of fashion items in the context of generation Z in Kazakhstan and to identify what kind of stimuli may affect the spontaneous decisions of centennials on buying apparel items. The methodology comprises six focus groups with 39 participants and an online survey which involved 106 centennials. The research was conducted in Almaty city among the population Z aged 18 and 22. The results indicate a prominent influence of Instagram in the everyday activities of respondents; moreover, it showed a positive correlation between this platform and the motivations of centennials to buy impulsively. The following results were obtained: 1) activities of fashion brands and friends' recommendations on Instagram act as stimuli on young consumers from generation Z; 2) activities of fashion brands and friends are likely to trigger positive reactions among centennials; 3) positive emotions derived from Instagram mainly can influence on centennials' impulsive purchases of fashion items. The outcome of this research can be helpful in the marketing departments of companies to understand the centennials' consuming habits and their use of social networks.
Assessment of the Sustainable Development of Regions: the Case of Kazakhstan
Authors: Kuanova Laura , Bekbossinova Assel , Abdykadyr Temirlan
Published: September 2023

This research work is devoted to assessing the sustainable development of regions in the example of Kazakhstan. Sustainable development is a strategically important aspect of the country, balancing economic growth, social well-being and environmental protection. The paper considers the key indicators used to assess the sustainable development of the regions of Kazakhstan. The Sustainable Development Goal Index (SDI) was calculated based on seven statistical indicators: gross regional product per capita, food security, unemployment rate, poverty rate, crime rate, education level, and environmental pollution in 14 regions and three cities from 2011 to 2021. The data was collected from the Bureau of National Statistics of Kazakhstan. The initial data of stability indicators were used as a matrix with dimensions m * n to calculate the weight coefficients. Further indicators were scaled and standardized. In addition, to evaluate the weighted index, a measure of the entropy of the indicator was calculated. As a result of the index calculation, it was revealed that the rating leaders are the regions with the lowest normalized poverty level, and these regions take the first place - the cities of Almaty, Astana and Shymkent. In comparison, the highest normalized poverty rate with the lowest positions are Turkestan, North Kazakhstan and Zhambyl regions. This work is essential for making effective decisions and developing targeted strategies for the sustainable development of Kazakhstan. It can be used as a basis for further research in the regional development sustainability field.
Factors Influencing Financial Management of Village Fund Allocation: Study in Lubai Ulu District
Authors: Periansya Periansya , Muamar M. , Aryani Yuli Antina
Published: September 2023

This research examines the impact of accountability, openness, and involvement on the financial management of village budget allocations in the Muara Enim district's Lubai ulu subdistrict. The sample included nine members of the village consultative committee from eleven communities within the subdistrict of Lubai Ulu. This study was conducted to assess how public accountability, transparency, and participation affect the administration of village budget allocations in the Muara Enim subdistrict of Lubai Ulu. The sample for this research consisted of 99 respondents from 11 villages in the Lubai ulu subdistrict. Respondents were chosen based on their direct involvement in reporting, decision-making, accountability, and administration in the financial management of local budget allocations. The result of this research was found accountability, transparency transparency, and participation partially have a positive and significant effect on the management of fund village allocations