bluuebunny/crossref_metadata_2025 huggingface dataset:
DETERMINING THE INTERVENTION STRATEGY FOR HERITAGE SHOPHOUSE FACADES AT IPOH, PERAK
Authors: Wan Ali Wan Nordiana , Mohd Zin Ida Nianti , Ibrahim Azira , Abdullah Halim Anas Zafirol , Ishak Noor Rizallinda , Talkis Nor Azizah
Published: June 2023

Nowadays, there are a large number of heritages shophouses remain intact in the major urban area in Malaysia, including Ipoh, Perak. However, some of the shophouses are facing inappropriate façade changes due to improper actions committed against the heritage property. The situation resulted in the phenomenon of inconsistency elements of building facades. This paper focuses on two aspects; first, identifying the improper actions committed against heritage shophouse facades compared to proper conservation approaches, and second, classifying the condition of the heritage shophouse facades to determine the current problems and dilemmas. From the literature review, five terms of improper actions are relevant; refurbishment, replacement, redesign, alteration, and deterioration. A pilot test involved twelve shophouses have been selected via purposive sampling. The results show that the terms are reliable to classify the condition of the shophouse facades. Most of the samples encounter dilemmas, mainly replacement and deterioration of the elements of the façade. The terms are also seen as relevant for a future heritage shophouse grading system for inventory purposes. The research findings may promote greater awareness among the owners, stakeholders, and the local authority on the prevailing situation experienced by the heritage shophouses.
Analytical capabilities of a thermodesorption spectrometer with a surface-ionization detection of organic molecules in air
Authors: Radjabov A. Sh.  , Khasanov U.  , Iskhakova S. S.  , Akhmedov Sh. M.  , Kakhramonova G. P.  , Akhunov Sh. Dj.  , Usmanov  D. T.
Published: June 2023

This paper presents the results of research on the development of a mathematical model of thermal desorption spectrometry with a surface ionization method for detecting molecules of organic substances, as well as an analysis of the capabilities of a thermal desorption spectrometer operating on the basis of this method. The mathematical model of the method was developed on the basis of the regularities of thermal desorption spectrometry, as well as the regularities of surface ionization of molecules of organic substances under non-stationary conditions. The spectrometer consists of a surface ionization detector and an evaporator of substances heated in a thermally programmed mode. The adjustment and selection of the operating mode of the spectrometer were carried out on the basis of the mathematical model of the method. The analytical capabilities of the spectrometer were studied by comparing the thermodesorption spectra of a mixture of chromatographically pure cannabinoids and an extract of the biological fluids of a marijuana user (blood, urine), as well as the spectra of chromatographically pure morphine and urine extracts of a heroin user. The results of the analysis showed the perspectives of the proposed method and instrument for the detection and analysis of drugs and psychotropic drugs in extracts of biomaterials of consumers of these substances without chromatographic separation. Keywords: biosamples of drug users, mathematical model of the method, thermal desorption spectrum, identification and quantitative analysis.
Features of macroscopic charge transfer in the ensembles of close-packed anatase nanoparticles near the percolation threshold
Authors: Zimnyakov D. A.  , Volchkov S.S.  , Varezhnikov A.S.  , Vasilkov M.Yu.  , Plugin I.A.
Published: June 2023

The results of experimental studies of the effect of degradation of macroscopic charge transport in ensembles of close-packed anatase nanoparticles under long-term action of a constant electric field are presented. The degradation is presumably due to the increasing degree of blocking of statistically independent conduction channels formed in ensembles of particles under the field action. A phenomenological model is considered for estimating the number of active conduction channels in an ensemble of particles near the percolation threshold in the system. Keywords: nanoparticles, anatase, charge transfer, percolation threshold.
The structure of the contact zone of the surfacing-substrate subjected to electron-beam processing
Authors: Ivanov Yu. F.  , Gromov V. E.  , Efimov M. O.  , Shliarova Yu. A.  , Panchenko I.A.  , Konovalov S.V.
Published: June 2023

Using scanning and transmission electron microscopy, the analysis of the structure, phase and elemental composition of the contact zone of the system coating (high-entropy FeCrCoNiMn alloy)-substrate (5083 alloy) after electron-beam processing was performed. The formation of a multiphase, multielement submicro- and nanocrystalline structure has been established. The structure of high-speed cellular crystallization in the contact layers adjacent to the coating and substrate is revealed, and the formation of lamellar crystals in the central region of the contact zone is also found. Keywords: contact zone, high-entropy alloy, wire-arc additive manufacturing method, 5083 aluminum alloy, pulsed electron beam, elemental and phase composition, structure.. Keywords: contact zone, high-entropy alloy, wire-arc additive manufacturing method, 5083 aluminum alloy, pulsed electron beam, elemental and phase composition, structure.
TELEMED: Database on Evidence-Based Telemedicine in a Hospital Setting
Authors: Wagner Svendsen Ida , Kidholm Kristian
Published: June 2023

Background

The use of telemedicine services has increased worldwide during recent years as a result of national strategies for the digitalization of health care and the COVID-19 pandemic. However, health care professionals often express uncertainty regarding the evidence and effectiveness of telemedicine interventions. Therefore, the Centre for Innovative Medical Technology at Odense University Hospital introduced the TELEMED database, an evidence-based telemedicine database.

Objective

This study aimed to ensure that hospital managers, health care professionals, and other stakeholders gain access to information about scientific studies of telemedicine interventions and their effectiveness.

Methods

The database constitutes a structured literature search in PubMed for randomized controlled trials or controlled trials on the effect of telemedicine for somatic diseases treated at hospitals. The search was conducted by staff members in the Health Technology Assessment unit at the Centre for Innovative Medical Technology. First, identified studies were sorted by screening titles and abstracts and, subsequently, by reading full-text versions. The data extracted from the studies included the setting, intervention, patient group, type of telemedicine, clinical effect, patient perception, and implementation challenges. Finally, the value of each study was assessed with respect to effectiveness.

Results

A total of 518 articles were included for data extraction and assessment. The database provides results from 22 different specialties and can be searched using the following criteria: medical specialty, country, technology, clinical effect, patient experience, and economic effect. The database serves as a platform for the dialogue with clinical departments who wish to implement telemedicine services and has a large potential for supporting the digital transformation during COVID-19 as evidence-based information on patient groups, relevant technologies, and their effect is easily accessible.

Conclusions

The TELEMED database provides an easily accessible overview of existing evidence-based telemedicine services. The database is freely available and is expected to be continuously improved and broadened over time.

Conflicts of Interest

None declared.
Graphical User Interface Development for a Hospital-Based Predictive Risk Tool: Protocol for a Co-Design Study
Authors: Marlow Nicholas , Eckert Marion , Sharplin Greg , Gwilt Ian , Carson-Chahhoud Kristin
Published: June 2023

Background

This co-design research method details the iterative process developed to identify health professional recommendations for the graphical user interface (GUI) of an artificial intelligence (AI)–enabled risk prediction tool. Driving the decision to include a co-design process is the belief that choices regarding the aesthetic and functionality of an intervention are best made by its intended users and that engaging these users in its design will promote the tool’s adoption and use.

Objective

The aim of this research is to identify health professional design and uptake recommendations for the GUI of an AI-enabled predictive risk tool.

Methods

We will hold 3 research phases, each consisting of 2 workshops with health professionals, between mid-2023 and mid-2024. A total of 6 health professionals will be sought per workshop, resulting in a total enrollment of 36 health professionals at the conclusion of the research. A total of 7 workshop activities have been scheduled across the 3 workshops; these include context of use, notifiers, format, AI survey–Likert, prototype, AI survey–written, and testing. The first 6 of these activities will be repeated in each workshop to enable the iterative development and refinement of GUI. The last activity (testing) will be performed in the final workshop to examine health professionals’ thoughts on the final GUI iteration. Qualitative and quantitative results data will be produced from tasks in each research activity. Qualitative data will be examined through inductive thematic analysis or deductive thematic analysis in accordance with the Nonadoption, Abandonment, and Challenges to the Scale-up, Spread, and Sustainability (NASSS) framework; visual data will be examined in accordance with “framework of interactivity;” and quantitative data will be examined using descriptive statistics.

Results

Project registration with the Australia and New Zealand Clinical Trial Registry has been requested (#384098). Finalized design recommendations are expected in early to mid-2024, with a results manuscript to be submitted in mid-2024. This research method has human research ethics approval from the South Australian Department of Health and Wellbeing (#2022/HRE00131) as well as from the Human Research Ethics Committee of the University of South Australia (application ID#204143).

Conclusions

Understanding whether an intervention is needed in a particular situation is just the start; designing an intervention so that it is used within that situation is paramount. This co-design process engages end users to create a GUI that includes the aesthetic and functional details they need in a manner that aligns with their existing work practices. Indeed, interventions that fail to do this may be disliked, and at worst, they may be dangerous.

International Registered Report Identifier (IRRID)

PRR1-10.2196/47717
Improving Telehealth Equity in Response to COVID-19 in California: ACTIVATE and Lighthouse (Preprint)
Authors: Lindeman David
Published: June 2023

BACKGROUND

In response to the significant stressors on health care delivery created by COVID-19, CITRIS Health and partner organizations developed 2 telehealth solutions through a rapid co-design process: Lighthouse and ACTIVATE. These programs were developed to support providers serving underserved and vulnerable populations who lack the tools and resources to support patients with chronic illness or who are isolated. These challenges were exacerbated by the COVID-19 pandemic, which increased the need for resources to support vulnerable patients who could not come into a clinic in person or were isolated and lacked access to services. ACTIVATE and Lighthouse apply 2 different telehealth strategies to reach vulnerable populations.

OBJECTIVE

This paper presents lessons learned from the design, development, and implementation of 2 innovative telehealth programs developed to improve health care delivery, access to care, digital literacy, and patient outcomes: ACTIVATE and Lighthouse.

METHODS

ACTIVATE is a comprehensive digital health pathway for community health centers that care for those who are medically underserved. ACTIVATE is an innovative, evidence-based, and sustainable telehealth program, designed to benefit vulnerable populations in rural and agricultural communities in the California Central Valley who experience significant health disparities. Lighthouse focuses on connecting older adults in congregate affordable housing, which are settings where residents are particularly vulnerable to isolation, the lack of health care resources, and limited to no access to the internet. Lighthouse provides digital literacy training as well as access to broadband internet with the goal of increasing communication, engagement, and access to health care.

RESULTS

This presentation will discuss successful design and implementation strategies as well as organizational and policy barriers to program operations.

CONCLUSIONS

In addition to reviewing program and implementation outcomes, strategies for replication and sustainability will be discussed. Although developed in response to COVID-19, the ultimate success of Lighthouse and ACTIVATE is dependent upon its successful scaling beyond the pandemic.
Retrieval-Based Diagnostic Decision Support: Mixed Methods Study (Preprint)
Authors: Abdullahi Tassallah , Mercurio Laura , Singh Ritambhara , Eickhoff Carsten
Published: June 2023

BACKGROUND

Diagnostic errors pose significant health risks and contribute to patient mortality. With the growing accessibility of electronic health records, machine learning models offer a promising avenue for enhancing diagnosis quality. Current research has primarily focused on a limited set of diseases with ample training data, neglecting diagnostic scenarios with limited data availability.

OBJECTIVE

This study aims to develop an information retrieval (IR)–based framework that accommodates data sparsity to facilitate broader diagnostic decision support.

METHODS

We introduced an IR-based diagnostic decision support framework called CliniqIR. It uses clinical text records, the Unified Medical Language System Metathesaurus, and 33 million PubMed abstracts to classify a broad spectrum of diagnoses independent of training data availability. CliniqIR is designed to be compatible with any IR framework. Therefore, we implemented it using both dense and sparse retrieval approaches. We compared CliniqIR’s performance to that of pretrained clinical transformer models such as Clinical Bidirectional Encoder Representations from Transformers (ClinicalBERT) in supervised and zero-shot settings. Subsequently, we combined the strength of supervised fine-tuned ClinicalBERT and CliniqIR to build an ensemble framework that delivers state-of-the-art diagnostic predictions.

RESULTS

On a complex diagnosis data set (DC3) without any training data, CliniqIR models returned the correct diagnosis within their top 3 predictions. On the Medical Information Mart for Intensive Care III data set, CliniqIR models surpassed ClinicalBERT in predicting diagnoses with <5 training samples by an average difference in mean reciprocal rank of 0.10. In a zero-shot setting where models received no disease-specific training, CliniqIR still outperformed the pretrained transformer models with a greater mean reciprocal rank of at least 0.10. Furthermore, in most conditions, our ensemble framework surpassed the performance of its individual components, demonstrating its enhanced ability to make precise diagnostic predictions.

CONCLUSIONS

Our experiments highlight the importance of IR in leveraging unstructured knowledge resources to identify infrequently encountered diagnoses. In addition, our ensemble framework benefits from combining the complementary strengths of the supervised and retrieval-based models to diagnose a broad spectrum of diseases.
Estimation of HIV Prevalence at the ZIP Code-Level Using Passive Surveillance Data and Social Determinants of Disease Spreading in Atlanta, Georgia: Bayesian Prediction Modeling. (Preprint)
Authors: Saldarriaga Enrique , Basu Anirban
Published: June 2023

BACKGROUND

Better information at the ZIP Code-level has the potential to enhance interventions targeting, identify treatment gaps, and optimize resources utilization. Currently there are no methods designed to estimate undiagnosed HIV cases at jurisdictions smaller than counties.

OBJECTIVE

This study aims to predict the number of undiagnosed HIV cases at the ZIP Code-level in Atlanta, Georgia, based on publicly available information.

METHODS

The CDC reports both passive surveillance (PS) and estimated total (MS) HIV cases for selected counties as part of the Ending of the HIV Epidemic initiative. We employed a Bayesian hierarchical model to: 1) Model MS as random draws from a Poisson distribution with mean equal to the true total HIV cases in the county. 2) A Binomial model for PS arising from the true denominator, with mean P, known as the ascertainment probability. 3) Use a logistic fractional model to allow P to be dependent on socio-economic determinants of HIV extracted from the American Community Survey. These determinants were chosen through a feature selection algorithm. The prediction model was tested out-of-sample on Georgia counties. Finally, we combined zip-code-level covariate data with the posterior predictive distribution of the logit coefficients to predict the mean P at zip-code-level. Final estimates were spatially-smoothed and aggregated to county-level for secondary validations.

RESULTS

The county-level model showed good mixing properties and predictive accuracy. The mean ascertainment probability calibrated to the ZIP Code-level varied from 78.4% (95% credibility interval: 24.4%-99.3%) to 93.8% (95%CI: 80.6%-99.8%). Further, the predicted undiagnosed HIV cases ranged between 12 (95%CI: 6-19; ZIP Code 30322) to 1,603 (95%CI 1,209-1,968; ZIP Code 30318).

CONCLUSIONS

Our findings provide a more detailed understanding of the risk profile of the city, in particular regarding the heterogeneity and concentration of cases within the city, and therefore a more complete picture of the transmission risk. This information could be leveraged to better identify underserved communities, better targeting the delivery of prevention and treatment services, and overall increase the efficiency in the control of the HIV epidemic. Furthermore, our methodological approach can be applied to other cities in the country, to obtain a more detailed depictions of its HIV risk-profile and complement passive surveillance efforts.

CLINICALTRIAL

NA
In Silico Analysis of Antibiotics Resistance Genes in Lactobacillus plantarum Kita-3 isolated from Halloumi Cheese
Authors: Wattimury Angelia , Suroto Dian Anggraini , Utami Tyas , Wikandari Rachma , Rahayu Endang Sutriswati
Published: June 2023

Previous studies found that antibiotics resistance genes on plasmids in Lactobacillus make them unsafe for food purposes due to the capability of genes to transfer to pathogenic microorganisms. In contrast, Lactobacillus is widely used as a probiotic. This study assessed the antibiotics susceptibility of Lactobacillus plantarum Kita-3 isolated from Halloumi cheese using eight antibiotics. Genome sequencing was performed using the NovaSeq 6000 sequencing platform to detect the presence of antibiotics resistance genes on chromosomes and plasmids. L. plantarum Kita-3 was resistant to clindamycin, streptomycin, chloramphenicol and susceptible to tetracycline, ampicillin, kanamycin, erythromycin, ciprofloxacin. Genome sequencing of the L. plantarum Kita-3 verified the presence of the tetracycline, fluoroquinolones, β-lactamase resistance genes, and multidrug resistance efflux. Kita-3 did not have transposable elements, gene transfer agents, and plasmid-related functions. Overall, this study resulted in the antibiotics resistance profile of L. plantarumKita-3 to assess the risk of antibiotics resistance genes transfer to other bacteria. This study can provide essential data on the safe use of Lactobacillus plantarum Kita-3 as probiotics.
Kajian Dampak Pajanan Radiasi Panas Saat Terjadi Tumpahan Minyak dan Kebakaran Tangki di Pusat Pengumpul Produksi Minyak PT. X
Authors: Sihotang Krisman J. , Widanarko Baiduri
Published: June 2023

Industri minyak memiliki risiko tinggi, kasus kejadian darurat seperti tumpahan minyak dan kebakaran di tangki pengumpul minyak sering terjadi dan digolongkan sebagai bahaya besar. Kejadian darurat ini dapat terjadi karena kegagalan safety protection layers (SPL) yang terpasang di tangki pengumpul minyak. Tangki yang terbakar akan mengakibatkan pajanan panas radiasi ke area sekitarnya termasuk area yang dihuni manusia. Tangki T-04 adalah salah satu tangki pengumpul minyak PT. X yang berpotensi mengalami kejadian darurat tersebut, untuk itu dilakukan kajian dampak pajanan panas radiasi kebakaran tangki T-04 terhadap fasilitas dan manusia di sekitarnya. Metode kajian yang dilakukan merupakan penelitian potong lintang dengan pendekatan kuantitatif untuk melakukan analisis dampak pajanan panas radiasi yang ditimbulkan kebakaran tangki T-04 terhadap fasilitas dan manusia sekitar. Penelitian ini dilakukan melalui pengumpulan data sekunder baik yang ada di PT. X dan studi literatur dengan tanpa melakukan intervensi pada objek penelitian. Data yang didapatkan tersebut dipergunakan untuk mengetahui dampak pajanan panas radiasi secara kuantitatif dengan menggunakan software ALOHA (Areal Location of Hazardous Atmosphere). Hasil penelitian menunjukkan kegagalan SPL terpasang di tangki T-04 berupa intervensi operator dan breather valve dapat mengakibatkan tumpahan minyak karena overfilled yang apabila ada sumber panas dapat menyebabkan tangki terbakar (tank fire engulfment). Hasil dari Layer of Protection Analysis (LOPA) diperoleh bahwa realisasi tank fire engulfment pada tangki T-04 dikategorikan sebagai kejadian dengan tingkat risiko yang tidak dapat diterima berdasarkan matriks risiko yang diacu PT. X. Simulasi kajian dampak pajanan panas radiasi kebakaran tangki T-04 terhadap fasilitas terdekat dan manusia sekitar dilakukan dengan menggunakan software ALOHA v.5.4.7. Diperoleh hasil pajanan panas radiasi di ruang operator pada jarak 45 m dari tangki T-04 sekitar 12,50 kW/ m2 yang berpotensi mengakibatkan kematian, ruang perkantoran yang berjarak 70 m dari tangki T-04 sekitar 6,44 kW/m2 yang berpotensi mengakibatkan luka bakar derajat dua, fasilitas umum jalan raya sekitar 2.5 kW/m2 berpotensi mengakibatkan sakit sementara, fasilitas tangki terdekat yaitu tangki T-03 berjarak 30 m sekitar 19.9 kW/ m2 akan mengalami domino effect ikut terbakar. Kajian ini memberikan rekomendasi untuk menambahkan Safety Protection Layers pada tangki penampung minyak PT. X untuk mengurangi risiko kebakaran menjadi risiko yang dapat diterima dengan memasang SPL yang sesuai yaitu PAH (Pressure Alarm High), LAH (Level Alarm High), SIS (Safety Instrumented System) seperti PAHH (Pressure Alarm High-High), dan LAHH (Level Alarm High-High).
Two Armies on a Colour (less) Plain: Tracing the Cultural Narratives of Amar Chitra Katha as a Colonial Embodiment
Authors: Anil Lakshmi
Published: June 2023

Despite a growing body of research on the media landscape in postcolonial India, Indian children’s media culture continues to be underrepresented in the field of history and popular culture. The world of comics and graphic novels shapes not just the minds of individuals but also the collective consciousness of communities and their unsung histories. Amar Chitra Katha has been an important cultural institution that has played a significant role in defining, for several generations of Indian readers on what it means to be an Indian. The paper seeks to address the politics of representation and the symbolic significance of the visual representation of different historical figures and events throughout the history of India. In today’s Indian society, love towards fair skin is seen in every spectrum of life, from songs to movies to marriages. Through this study I will explore how all these variables are linked and connected over the period of time with the skin tone preference thereby re-writing the essence of ‘Indianness’. The historical representations of this comic book tradition render Amar Chitra Katha a crucial resource to understand paradigm shift in the ways the nation imagines itself.
Establishing a new workflow in the study of core reduction intensity and distribution
Authors: Lombao Diego , Rabuñal José Ramón , Cueva-Temprana Arturo , Mosquera Marina , Morales Juan Ignacio
Published: June 2023

New methodological approaches focused on studying the reduction and use-life of stone tools have emerged in recent years, enabling researchers to move beyond strict technical and technological characterizations and explore specific aspects of occupation dynamics and economic management of resources. Previous studies have shown the importance of reduction distributions of individual measurements rather than averaged values. In this sense, survival analysis, and more specifically Weibull distributions, are one of the main inferential tools used in reduction studies. However, the resolution of Weibull distribution obtained from different methods has not been tested experimentally. In this paper, we present an evaluation of some of the main methods used in the study of core reduction intensity, such as the Volumetric Reconstruction Method, the Scar Density Index, and the non-cortical surface percentage. Our results show 1) strong and positive correlations between these approaches and actual reduction intensity, 2) similar Weibull distributions for non-cortical surface percentage, Volumetric Reconstruction Method, and logarithmic transformation of Scar Density Index. In addition, 3) the results from each method show a similar intra-assemblage variation, with a high percentage of agreement between them.
As a result, all the evaluated proposals are useful and reliable methods for estimating the degree of reduction. Finally, a workflow is proposed for approaching reduction in archaeological assemblages by integrating different methods in the same study.
Prueba de la marcha: Respuestas ventilatorias, cardiovasculares y relación con la distancia recorrida en pacientes con secuelas de tuberculosis
Authors: Betancourt-Peña Jhonatan , Molano-Murillo Juan , Lopez Ingrid Lorena , Ávila-Valencia Juan
Published: June 2023

Introducción: La evaluación de los pacientes con tuberculosis pulmonar permite establecer metas de intervención en salud; el test de caminata de los 6 minutos, es ideal para observar la respuesta de todos los sistemas incluidos durante el ejercicio. Objetivo: Describir la respuesta fisiológica de algunas variables ventilatorias y cardiovasculares durante el test de caminata de los 6 minutos en pacientes con secuelas de tuberculosis pulmonar, y sus posibles correlaciones de las variables fisiológicas con la distancia recorrida. Materiales y métodos: Estudio descriptivo de corte transversal en 21 pacientes con diagnóstico de secuelas de tuberculosis pulmonar, quienes asistieron a un programa de rehabilitación pulmonar, y realizaron test de caminata de los 6 minutos. Resultados: La edad media fue 49,33±18,82 años, en su mayoría hombres, la media de la distancia fue 348,35±127,833m. Hubo diferencia significativa durante los cuatro momentos analizados con un valor p<0,0001 en frecuencia cardiaca, frecuencia respiratoria y saturación de oxígeno. Hubo correlación fuerte para la edad, consumo de Oxígeno (VO2), número de detenciones, disnea modified Medical Research Council (mMRC), capacidad funcional medida en equivalentes Metabólicos (METS) y Saturación de Oxígeno (SpO2). Conclusión: Pacientes con secuelas de tuberculosis pulmonar en su mayoría hombres, evidencian cambios estadísticamente significativos durante la prueba.
Analisis Pandangan Abdul Moqsith Ghazali dan Hamid Fahmy Zarkasyi terhadap Pluralisme Agama dalam Penafsiran Ayat-Ayat Al-Quran
Authors: Hidayatullah Fauzan
Published: June 2023

The issue of religious pluralism continues to resonate in the millennial era. In this context, Abdul Moqsith Ghazali and Hamid Fahmy Zarkasyi are two contemporary figures whose perspectives and interpretations of Quranic verses related to religious pluralism are relevant for further examination. The aim of this research is to analyze the views of both figures on religious pluralism and their interpretations of verses regarding the salvation of religious communities found in Surah Al-Baqarah [2]:62 and Surah Al-Maidah [5]:69. This study employs a library research method, utilizing primary data from Abdul Moqsith Ghazali's work, "Argumen Pluralisme Agama" (Arguments for Religious Pluralism), and Hamid Fahmi Zarkasyi's works, "Misykat" and "Pluralisme Agama" (Religious Pluralism). Secondary data includes Tafsir literature and other relevant sources.. The findings of this research indicate that, in terms of interpretation, Hamid's perspective is more comprehensive and objective. However, within the context of interreligious harmony, Abdul Moqsith's viewpoint is more contextual and better aligned with the realities of society.bergaung hingga era millennial saat ini. Dalam konteks ini, Abdul Moqsith Ghazali dan Hamid Fahmy Zarkasyi merupakan dua tokoh kontemporer yang relevan untuk dikaji pandangan dan penafsiran mereka terhadap ayat-ayat Al-Quran yang berkaitan dengan pluralisme agama. Tujuan penelitian ini adalah menganalisis pandangan kedua tokoh tersebut terhadap pluralisme agama dan penafsiran mereka terhadap ayat-ayat tentang keselamatan umat beragama yang terdapat pada QS. Al-Baqarah [2]:62 dan QS. Al-Maidah [5]:69. Metode penelitian menggunakan studi kepustakaan dengan data primer berupa karya Abdul Moqsith Ghazali: "Argumen Pluralisme Agama" dan karya Hamid Fahmi Zarkasyi: "Misykat" dan "Pluralisme Agama". Data sekunder yang digunakan meliputi kitab tafsir dan sumber-sumber relevan lainnya. Hasil penelitian menunjukkan bahwa dari segi penafsiran, pandangan Hamid lebih komprehensif dan objektif. Namun, dalam konteks kerukunan umat beragama, pendapat Abdul Moqsith lebih kontekstual dan lebih dapat diterima oleh realitas masyarakat.
Evaluating graphing quadratic worksheet on visual thinking classification: A confirmatory analysis
Authors: Oktaviyanthi Rina , Agus Ria Noviana
Published: June 2023

Applying a graphing quadratic worksheet as a medium for learning the concept of a Quadratic Function clearer is an alternative instrument to accommodate the needs of developing students' mathematical visual thinking. In implementing graphing quadratic worksheet should show details of the dominant and recessive visual thinking classification aspects that develop in students. Classification of dominant and recessive aspects of visual thinking needs to be completed to determine stages in improving the worksheet and learning instructions that are applied especially to recessive aspects. Therefore, there is a need to evaluate the factors and trace the classification aspects of visual thinking that developed in students after practicing the graphing quadratic worksheet. The purpose of this research is to determine the categorization aspects of visual thinking in graphing quadratic worksheet items that develop and do not develop in students. Confirmatory factor analysis was employed as a research method on 12 sub-variables from the three classifications of visual thinking. As research data, 93 student records were used. Four main factors were formed as a result of the confirmatory factor analysis procedure, with the top two factors, namely factors 1 and 2, completely representing each aspect of the visual thinking classification and achieving the factor loading significance criteria. The implication is that the variables developed in the graphing quadratic worksheet for each aspect of the visual thinking classification have a strong relationship with the visual thinking ability overall. Enhanced by a cumulative variance value for factors 1 and 2 specifically 56.88% of the total 81.78% for all factors. Thereby it can be said that the categorization aspect of visual thinking that develops in students after implementing a graphing quadratic worksheet is achieved sensibly.
Analisis kadar mineral mikro tembaga dan besi pada biji durian
Authors: Lestari Ayu , Said Irwan
Published: June 2023

This study aims to determine the levels of copper and iron contained in durian seeds, determine the levels of copper and iron using Atomic Absorption Spectrophotometer (AAS). The results showed that the analysis of the water content of durian seeds obtained 37.382%, ash content 17.782% and mass 44.835%. Analysis of the iron content measured at the copper wavelength of 248,3 nm, at the wavelength of 249,2, the results obtained respectively 49.244 ± 116.076 mg/100g for copper and 66.495± 15.753  mg/100g for iron. The results of this study are expected to be one of the alternative food ingredients that can be processed into food to meet the copper and iron substances in the body.
Aktivitas Antioksidan Pada Buah, Tepung, dan Biskuit Berbasis Labu Siam (Sechium edule)
Authors: Fajriani Fajriani , Sakung Jamaludin
Published: June 2023

Labu siam atau Sechium edule merupakan salah satu tanaman Indonesia dan merupakan komoditas pangan yang potensial untuk dijadikan sebagai bahan utama pengembangan produk, labu siam merupakan tanaman yang hidup di daerah tropis dan sub tropis. Penelitian ini bertujuan untuk mengetahui kandungan antioksidan buah, tepung dan biskuit labu siam menggunakan spektrofotometri UV-Vis. Analisis kandungan antioksidan pada penelitian ini menggunakan metode DPPH (1,1-diphenyl-2-picrylhydrazil) sebagai sumber radikal bebas. Ekstrak buah, tepung dan biskuit labu siam dianalisis kandungan antioksidannya dengan variasi konsentrasi 20 ppm, 40 ppm, 60 ppm, 80 ppm, 100 ppm. Hasil yang diperoleh ekstrak buah labu siam mentah memiliki kandungan antioksidan sangat lemah dengan nilai IC50 rata-rata 256,723 ppm, tepung labu siam memiliki kandungan antioksidan sedang dengan nilai rata-rata IC50 140,999 dan biskuit labu siam memiliki kandungan antioksidan lemah dengan nilai rata-rata IC50 adalah 179,619 ppm
Caracterización morfológica de la diversidad genética de arracachas (Arracacia xanthorhiza Bancroft.) recolectadas en el eje cafetero colombiano
Authors: Tabares Alvarez Diego Fernando , Polanco Puerta Manuel Francisco
Published: June 2023

Contextualización: Colombia posee es parte de la diversidad genética primaria de distintas especies del género Arracacia, entre las que se destaca Arracacia xanthorrhiza [conocida como arracacha]. Esta especie es fuente de carbohidratos, vitaminas y minerales, presentando un gran potencial para la industria de harinas y almidones y el uso culinario.
Vacío de investigación: Sin embargo, esta planta es poco valorada y la información sobre su variabilidad genética y potencial de mejoramiento es escasa.
Propósito: Esta investigación tuvo como objetivo caracterizar la variabilidad genética y, consecuentemente, identificar y seleccionar genotipos promisorios de la colección de germoplasma de Arracacha con la que cuenta la Universidad Nacional Abierta y a Distancia [UNAD] en la Sede de Dosquebradas Risaralda Colombia. La colección está compuesta por 39 accesiones colectadas en la región del eje cafetero [Norte del Valle del Cauca, Quindío, Risaralda, Caldas, y Tolima].
Metodología: Para la evaluación de los caracteres se empleó el listado de descriptores desarrollado por el Centro Internacional de la Papa, modificado por el Programa Nacional de Recursos Fitogenéticos de Agrosavia. La caracterización se realizó en cinco plantas por parcela experimental; los descriptores de la parte aérea se evaluaron en plantas adultas y los de las raíces reservantes se examinaron al momento de la cosecha [aproximadamente 12 meses después de la siembra].
Resultados y conclusiones: Se dedujo que las 39 accesiones con que cuenta la colección de arracacha de la UNAD se pueden descomponer en 4 grupos; de los cuales, las accesiones D25, D8, V19, D13, D14, R23, y D16 fueron las más promisorias en cuanto a la producción de biomasa en los tubérculos. Con la variabilidad encontrada no se puede precisar el patrón de distribución de la especie en la región, pero el gran número de caracteres cualitativos y cuantitativos encontrados permite suponer que existen genotipos promisorios con los que se pueden establecer programas de mejoramiento agronómico de la especie.
LANGUAGE ATTITUDE AND SENTIMENT ANALYSES IN GETTING THE INSIGHTS TOWARDS COVID-19’S OMICRON VARIANT NEWS
Authors: Mulia Vilya Lakstian Catra , Naury Chairullah , Purnamasari Ika , Meiliana Libel
Published: June 2023

Omicron variant has been massively reported on Indonesian mass media following the spread of other previous variants during Covid-19 pandemic. This research combines computer science and linguistics to analyze the news on the variant. It implemented quantitative research using computational algorithm by collecting the titles of the news from Indonesian mainstream online mass media. Sentiment Analysis (SA) was applied to obtain the sentiments, opinion, and subjectivities of the texts along with topic modeling in classifying the topics. The words in the headline news titles were used as the data and grabbed by Python programming language. A criterion-based sampling was employed in to select the relevant data and to formulate the criteria in the research methodology. The results were filtered to ‘Omicron’ keyword for SA processing by the Azure Text Sentiment Analysis tool. The results of SA, as computational research, was then confirmed with Attitude Analysis (AA) from the perspective of Systemic Functional Linguistics. AA classified the words into affect, judgment, and appreciation as the attitude construed in English text. This research provides SA as the insights of Omicron issue. The presence of AA extracts the words into bipolar senses of human’s meaning interpretation. AA is important to straighten SA findings. SA has contextual meaning problem and requires study on its words classified in ‘neutral’ which are then confidently directed into positive or negative meanings by AA. It is found that there are different dynamics by SA and AA findings as they reflect particular meanings. Besides their difference, SA is useful for managing overload data into fast policy making whereas AA makes sure the acceptable meanings to people. In this case AA corrects the bias occurring from SA.
PaCO2 at Early Stage is Associated with Adverse Cardiovascular Events in Acute Carbon Monoxide Poisoning
Authors: Yang Keun Mo , Chun Byeong Jo , Moon Jeong Mi , Cho Young Soo
Published: June 2023

Purpose: The objective was to determine the association between PaCO2 and adverse cardiovascular events (ACVEs) in carbon monoxide (CO)-poisoned patients. Methods: This retrospective study included 194 self-breathing patients after CO poisoning with an indication for hyperbaric oxygen therapy and available arterial blood gas analysis at presentation and 6 hours later. The baseline characteristics and clinical course during hospitalization were collected and compared. The mean PaCO2 during the first 6 hours after presentation was calculated. Results: The incidence rates of moderate (30 mmHg< PaCO2 <35 mmHg) or severe (PaCO2 ≤30 mmHg) hypocapnia at presentation after acute CO poisoning were 40.7% and 26.8%, respectively. The mean PaCO2 during the first 6 hours was 33 (31-36.7) mmHg. The incidence of ACVEs during hospitalization was 50.5%. A significant linear trend in the incidence of ACVEs was observed across the total ranges of PaCO2 variables. In multivariate regression analysis, mean PaCO2 was independently associated with ACVEs (OR 0.798 (95% CI 0.641-0.997)). Conclusion: Mean PaCO2 during the first 6 hours was associated with increased ACVEs. Given the high incidence of ACVEs and PaCO2 derangement and the observed association between PaCO2 and ACVEs, this study suggests that 1) PaCO2 should be monitored at the acute stage to predict and/or prevent ACVEs; and 2) further study is needed to validate this result and investigate early manipulation of PaCO2 as treatment.
Severity Predictors of Elderly Poisoning Patients Admitted to an Emergency Medical Center
Authors: Park Chang Yong , Cha Kyung Man , So Byung Hak , Jeong Won Jung
Published: June 2023

Purpose: This study examined the clinical characteristics of severe elderly poisoning patients to determine the factors that can prevent them. Methods: Data were collected from patients over 65 years of age presenting to the emergency center with poisoning from 2013 to 2018. Their medical records were analyzed retrospectively, and patients with a poisoning severity score of three or more were defined as the severe poisoning group. The risk factors were evaluated by univariate and multivariate analysis. Results: This study analyzed 292 patients, of whom 37 (12.7%) belonged to the severe poisoning group. The severe poisoning group showed a significantly higher association with pesticide poisoning and intentional suicide attempts. Loneliness and somatization were the cause of the suicidal ideas. No significant differences in age, sex, drinking, ingestion time, poisonous materials other than pesticides, and neuropsychological consultation were observed between the two groups. Conclusion: The severe elderly poisoning patients were the result of intentional poisoning for suicide. Loneliness and somatization were the most influential causes of suicidal poisoning. Therefore, psychiatric screening and frequent medical treatment for elderly people are required to prevent severe poisoning in elderly patients.
Chlorine dioxide solution in metastatic cancer: case series
Authors: Aparicio-Alonso Manuel , Schwartz Laurent , Torres-Solórzano Verónica
Published: June 2023

Chlorine dioxide is a potent oxidant with in vitro anticancer
activity. Its precise mechanism of action has not been thoroughly
explored, but it is proposed that it acts through the redox imbalance of
cancer cells. Three patients were treated for metastatic cancer (kidney,
prostate, lymphoma, uterus and melanoma), on a compassionate basis. We
report lasting tumor response with a combination of oral, enema and/or
intravenous chlorine dioxide, without side effects. The patients had
refused conventional chemotherapy, radiation therapy or immunotherapy.
This preliminary work suggest that chlorine dioxide and his free
radicals might be the mediators. Chlorine dioxide is both a promising
and unexpensive anticancer agent. Rigorous clinical trials are needed to
confirm these preliminary results.

Keywords: Chlorine dioxide solution, cancer, reactive oxygen
species, intermittent fasting, ketogenic diet
Effect of COVID-19 on autism spectrum disorders: A bibliometric analysis based on original articles
Authors: Jiangshan Li , Kaifeng Lyu , Min Chen , Wei Zhang , Meichao Hu
Published: June 2023

objective: The objective of this bibliometric inquiry was to scrutinize
domains that delve into the repercussions of the COVID-19 pandemic on
individuals afflicted with ASD, worldwide scholarly findings of
interrelated research, and forthcoming trajectories. Method. To
perform a literature analysis, the Web of Science Core Collection
(WoScc) database is recommended. Look for literature related to ASD and
COVID-19. For visual analysis and network creation of authors,
organizations, countries, and keywords, CiteSpace and VosViewer can be
utilized. Result. This study analyzed 771 papers and found
increasing publications, with the United States, United Kingdom, and
Italy leading in relevant literature. The University of London and
Happe_Francesca were the most productive in terms of papers and
researchers, respectively. Research on the impact of COVID-19 on autism
spectrum disorder was mainly found in J AUTISM DEV DISORD. Parenting
stress, enhancing adherence, and acute stress disorder were popular
topics of investigation. Future research may focus on interventions,
qualitative research, Disabilities Monitoring Network,
neurodevelopmental disabilities, perceived stress, and barriers.
Conclusion. This bibliometric analysis delineates the
fundamental structure for assessing the impact of COVID-19 on ASD by
scrutinizing crucial indicators. Future research could explore the
stress, anxiety, and strategies for individuals with ASD and their The
use of telemedicine can be studied in depth, as a new idea for ASD
diagnosis and intervention training, it is worthwhile. The use of
telemedicine can be studied in depth, as a new idea for ASD diagnosis
and intervention training, it is worth exploring, such as Disabilities
Monitoring Network, etc.
The Impact of Digital Marketing on Consumer Buying Intention - A case study of Pakistan
Authors: Ahmed Bilal , Rashid Sara
Published: June 2023

This research examines the influence of digital marketing, particularly social media, mobile, and Email marketing, on consumer purchasing intentions within Pakistan’s textile industry. Utilizing a quantitative method coupled with a causal explanatory research design, this study aims to quantify the impact of digital marketing strategies on consumer purchasing behaviors. Data was collected from a sample of 228 participants, chosen through judgment sampling. This data was then subjected to regression analysis via Statistical Package for the Social Sciences (SPSS). The findings indicate that social media and Email marketing influence consumer purchasing intentions. However, the empirical evidence drawn from the sampled data did not support the effect of email marketing on consumer purchasing intentions. This research offers substantial theoretical and practical implications, further contributing to the existing body of knowledge
Ethics and Gender Specificities in Diseases Transmitted by Mosquitoes
Authors: MJC Tamayo
Published: June 2023

Emerging diseases, caused by mosquitoes, affect people asymmetrically, therefore it is pertinent to study this problem with a gender approach, as it is important not only to carry out an epidemiological follow-up of these diseases, but it is also essential to analyze the economic, psychological, cultural and social factors associated with gender in the affectation that they cause or that make women and girls more vulnerable before them. For this reason, gender emerges as an explanatory element of the roles that men and women play in the different spheres: domestic, community, and social, which shape the risks of exposure to these vectors and open prospects for success in prevention, control, and management of these diseases. In this sense, ethics becomes an essential analytical and practical tool to determine that the real inequality between genders and the mechanisms of social discrimination that feed it place women in conditions of vulnerability regarding these diseases; which above all it is a question of justice and equity; therefore ethical.