bluuebunny/crossref_metadata_2025 huggingface dataset:
Determination Of Awareness and Knowledge Level on Brain Death, Organ Donation and Transplantation in Intensive Careers in Konya
Authors: TOMRUK Mustafa , GÖK Funda , EROĞLU Esma
Published: July 2023

Aim: It is shown that there is a lack of social and individual information on organ transplantation and donation, and as a result, organ donation is not sufficient due to social and individual insensitivity. In our study, we aimed to evaluate the level of awareness, attitude and knowledge about brain death, organ donation and transplantation in intensive care workers of hospitals in xxxx.

Materials and Methods: A total of 219 healthcare professionals, 144 nurses and 75 doctors, who agreed to meet face-to-face with the researcher, who were working in xxxx province state hospitals, university hospitals and private hospital intensive care units, were included in the study. The data of the study were collected using the 'Data Collection Form', which was created as a result of the literature review and includes demographic information.

Results: A total of 219 health care workers participated in the study with 144 (65.8%) intensive care nurses and 75 (34.2%) intensive care physicians. There was an organ donation card of 13.2% (n: 29) of the participants. There were 16,7% (n: 24) nurses and 6,7% (n: 5) doctor donation cards in doctors. In the case of brain death, 56.9% of participants wanted their organs to be donated. In the case of brain death, 58.7 of those who did not accept organ donation did not feel ready. 21% (n: 46) previously participated in organ / tissue donation and transplantation, 16.9% (n: 37) previously participated in brain death related trainings. Among the doctors who participated in the study 37.8% (n: 28) Electroencephalography (74%) and Radionuclide Cerebral Scintigraphy (62%) are the most common supportive tests used for the diagnosis of brain death.

Discusion: Nursing and doctors' support of tissue / organ donation and transportation does not affect having donation card. There is no significant difference between the general knowledge levels of anesthesia and other branch physicians about brain death, but anesthesia doctors have been found to be more experienced in diagnosing brain death. We believe that the positive attitudes of the intensive care workers on this subject and the sufficient level of knowledge will positively affect the amount of organ donation.
CERCLAGE OUTCOME DEPENDING ON SUTURE MATERIAL CHOICE, EFFECTS ON BIRTH WEEK, INFANT WEIGHT, INTENSIVE CARE REQUIREMENT, AND INFECTION RATES
Authors: ACAR Züat , OMURCA Fatih , ÇAVUŞ Yunus
Published: July 2023

Aim: A preterm birth (PTB) is one that occurs before the full 37th week of pregnancy. Our theory is based on the possibility that braided mesh sutures made of Mersilene could lead to more complications and undesirable outcomes.

Methods: There were 46 pregnant women who had cervical insufficiency. Mersilene sutures were used in 26 cases and prolene sutures in 20 cases. The cervical lengths were comparable.

Results: Each case involved a pregnancy with a single fetus. Mersilene and prolene were the suture types in 26 cases and 20 cases, respectively. During the monitoring period, no problems, including infections, were noted.

Conclusion: Prolene sutures appear to be related with decreased PTB and improved neonatal results, despite the fact that mersilene sutures are the conventionally chosen material for cerclage. Prolene sutures continue to offer an option to conventional mersilene sutures, notwithstanding the need for more thorough randomized clinical trials to identify any potential associations between suture material and cerclage outcomes.
Oncological outcomes in geriatric patients with early stage gynecological cancer who underwent surgery and radiotherapy
Authors: YILDIRIM Berna , GÜRDAL Necla
Published: July 2023

ABSTRACT

Background:

Evaluation of oncological results obtained with surgery and adjuvant radiotherapy in geriatric patient group with early stage gynecological cancer.

Methods:

31 patients aged 65 years and older who were operated for early stage gynecological cancer and had adjuvant radiotherapy were included in the study. All patients were evaluated in terms of general characteristics, local and systemic treatments, and oncological outcomes.

Results:

Percentages of patients diagnosed with endometrium ca and cervix ca are 80.6% and 19.4%, respectively. The median age of the patients was 69 (range, 65-86). All patients underwent total abdominal hysterectomy and bilateral salpingo oophorectomy, followed by adjuvant pelvic radiotherapy. Intracavitary vaginal brachytherapy was applied to 90.3% of the patients. At a median follow-up of 69 months, 3.2% of patients had local recurrence and 3.2% had distant metastases. The five-year DFS and OS rates were 93% and 80%, respectively

Conclusions:

Treatment planning in geriatric patient group should be shaped according to prognostic factors, age group and comorbidity. Remarkable oncological results can be obtained with multimodality treatments in the selected patient group.
Frequency and seasonal distribution of rotavirus and adenovirus in patients with acute gastroenteritis
Authors: KIRCA Füsun , DEMİREL Filiz
Published: July 2023

Aims

The aim of this study was to retrospectively determine the frequency of rotavirus and adenovirus and the distribution of these pathogens by age groups, gender and season in patients admitted to our hospital with gastroenteritis symptoms.

Materials and Methods

A total of 32755 stool samples collected from patients with gastroenteritis symptoms in the Medical Microbiology Clinic of the Hospital between January 1 and December 31, 2022 were evaluated retrospectively for rotavirus and adenovirus antigens. Rotavirus and adenovirus antigens were analyzed with the Rapid Cassette Test (Microcult, Biotech) kit. In addition, the distribution of pathogens by age groups, gender and season were examined. Statistical analysis was performed using Jamovi® version 2.3.21.

Results

Antigen test was positive in 9.9% of 32755 stool samples evaluated in our study. Rotavirus was detected in 8.4% and adenovirus in 1.5% of antigen positive samples. Both rotavirus and adenovirus antigen positivity were found to be statistically significantly higher in 0-1 and 2-3 age groups compared to other age groups (p
Comparative Evaluation of the Effects of Sevoflurane and/or Dexmedetomidine on Behavior, Neuro-inflammation and Apoptosis in Pups Rat
Authors: TURHAN Semin , İNAN Arda , IŞIK Berrin
Published: July 2023

Aim: Developing brain is vulnerable to side effects of anesthetics. Neurotoxic and cognitive alterations have been documented in several species, and there is concern that small children could be affected adversely if they are exposed for long periods or recurrently to inhalation anesthesia In this experiment we aim to evaluate behavioral and neurotoxic effects of sevoflurane (SEVO) and/or dexmedetomidine (DEX) exposure in pup rats.

Materials and method: Postnatal 21 days old 36 rat were randomly divided into 6 groups (Group I (control); Group II:2.5% SEVO for 4 hours; Group III:2.5% SEVO for 4 hours+intraperitoneal (i.p.) 0.5 µg.kg-1 DEX; Group IV:2.5% SEVO for 4 hours+i.p. 5 µg.kg-1 DEX; Group V: i.p. 0.5 µg.kg-1 DEX; Group VI: i.p. 5 µg.kg-1 DEX was given). Behavior of the rat were examined with the modified Radial Arm Maze test. Histopathological evaluation of the pups’ rat brain for neuroinflammation and apoptosis was performed. Statistical evaluation was carried out using the SPSS 20.0, P value
Comparison of the Effects of Clinical Outcomes on the Number of Attacks in the Course of Ulcerative Colitis: A Single Center Study
Authors: ŞIVGIN Hakan , ŞAHİN Abdurrahman , ÇETİN Şirin
Published: July 2023

Aim: The aim of this study was to find the factors affecting the frequency of attacks of patients diagnosed with ulcerative colitis (UC).

Method: In our single-center retrospective descriptive study, 40 UC patients who admitted to our hospital for follow-up from January 2021 to December 2022. The baseline demographic and clinical characteristics, laboratory values and, treatments during the disease course were compared among patients with number of attacks < 2 per year ( Group1) and number of attacks ≥2 per year ( Group 2).

Results: There were 25 (male∕female:11∕14) patients in Group 1 and 15 (male∕female:7∕8) patients in Group 2. No statistically significant difference was found between the mean age, sex, age of diagnosis, duration of disease, co-morbidities and extraintestinal involvement of both groups. The median CRP values were significantly higher in the Group 2, compared to the group 1 (P = 0.04). There was statistically significant differences between groups in terms of endoscopic severe activity (12% vs, 40%; p
Effects of Caffeine Use in Hemifacial Spasm Patients
Authors: KARA Mehmet , KILIÇ Soner
Published: July 2023

Abstract

Objective: Hemifacial spasm is characterized by progressive, involuntary, irregular contraction of the muscles innervated by the facial nerve. Caffeine is a phytochemical that increases muscle contraction and neurotransmitter release. The aim of this study is to evaluate the effects of caffeine-containing food consumption on disease severity and disease-related quality of life in patients with hemifacial spasm.

Materials and Methods: In hemifacial spasm patients who applied to the neurology outpatient clinic; hemifacial spasm quality of life scale and hemifacial spasm severity scale were evaluated prospectively. The amount of caffeine taken by the patients with daily food and beverage was determined. The relationship between the results of the scales and the amount of caffeine consumed was analyzed.

Results: A total of 60 patients, 36 women (60%) and 24 men (40%), were included in the study. It was determined that 59 of the patients (98.3%) consumed an average of 303±144 mg/day of caffeine with food. The hemifacial spasm quality of life scale score was calculated as 8.5 (4-21) and the hemifacial spasm severity scale was calculated as 3 (1-4). No significant correlation was found between the amount of caffeine consumed by gender (p=0.066). A negative correlation was found between the amount of caffeine consumed by age (r=-0.291; p=0.024). There was no significant relationship between daily caffeine consumption and hemifacial spasm quality of life scale and hemifacial spasm severity (p values 0.297 and 0.839, respectively). There is a weak positive correlation between the hemifacial spasm quality of life scale and the severity of hemifacial spasm (r=0.291; p=0.024).

Conclusion: It has been determined that the consumption of foods containing caffeine in daily life does not affect the severity of spasm and quality of life in patients with hemifacial spasm.
Determinantes da divulgação dos principais assuntos de auditoria nas companhias não financeiras da B3
Authors: Dal Bem Venturini Lauren , Alberto Barbetta Pedro , Alonso Borba José , Flach Leonardo
Published: July 2023

Esta pesquisa analisa os determinantes da quantidade de principais assuntos de auditoria (PAA) reportados nos relatórios de auditoria no período de 2016 a 2019 das empresas não financeiras listadas na B3. Aplicou-se o modelo longitudinal de regressão para dados em painel - Log-Linear de Poisson, para uma amostra anual de no mínimo 272 companhias, resultando em 1.198 relatórios e 3.295 PAA (variável dependente), considerando como variáveis explicativas os aspectos do auditor, do auditado e mecanismos de governança corporativa. Os achados demonstram que ser auditado por big four está negativamente associado ao quantitativo de PAA. Isso pode ocorrer devido as big four ou não relatarem mesmo número médio de PAA por companhia. Auditores de empresas maiores, menos rentáveis e, com maior risco operacional divulgam mais PAA, provavelmente visando assegurar sua independência. Os comitês de auditoria não foram estatisticamente significativos, não impactando na quantidade de PAA reportados. Os resultados contribuem com a literatura sobre fatores que afetam a divulgação de PAA em um contexto não europeu (Bepari et al., 2022) com quatro anos de dados, e às empresas, auditores e órgãos de regulação e supervisão, por meio da regressão multinível de Poisson, que é uma abordagem adequada para dados de contagem estruturados em clusters de observações relativamente similares (painéis). Isso avança os estudos de Ferreira e Morais (2020) e Guedes et al. (2021) que utilizaram ordinary least squares (OLS) e Colares et al. (2020) que empregou o teste Qui-quadrado em análises de um ou dois anos de características que tendem a estabelecer a quantidade de PAA no Brasil.
Nature of the abnormally high photocurrent relaxation time in the a-Ga2O3-based Schottky diodes
Authors: Schemerov I. V. , Polyakov A. Yu. , Almaev A. V. , Nikolaev V. I. , Kobeleva S. P. , Vasilyev A. A. , Kirilov V. D. , Kochkova A. I. , Kopiev V. V. , Kulanchikov Yu. O.
Published: July 2023

Ga2O3 is an ultra-wideband material with excellent optical characteristics. It is a promising material for power applications and optoelectronics because of its high electrical breakdown voltage and radiation hardness. It is optically transparent for visible light and UVA but UVC-sensitive. One of the main disadvantages of this material is the anomalous slow photoeffect: photoconductivity rise and decay characteristic times can be more than hundreds of seconds long. This "slow" photoconductivity effect severely limits the utilisation of the Ga2O3-based devices. The aim of this work is the investigation of the nature of this effect. The results of the photoinduced current rise and decay under 530 nm and 259 nm LED are measured in the HVPE-grown α-Ga2O3-based Schottky diode. Upon UV-illumination the photocurrent rise consists of three parallel processes: fast signal growth, slow growth and very slow decay with characteristic times near 70 ms, 40 s and 300 s respectively. Subsequent 530 nm LED illumination resulted in photoinduced current rise consisting of two mechanisms with characterisatic times 130 ms and 40 s on which a very slow decrease of the photocurrent amplitude with characteristic time of 1500 s was superimposed. 530 nm illumination stimulates this process. Protoinduced current relaxation analysis shows the presence of the deep levels with energies (EC - 0.17 eV). It is suggested that extremely slow relaxations can be associated with potential fluctuations near the Schottky barrier.
Impact of nanosecond UV laser pulses on the surface of germanium single crystals
Authors: Zheleznov V. Yu. , Malinsky T. V. , Rogalin V. E. , Khomich Yu. V. , Yamshchikov V. A. , Kaplunov I. A. , Ivanova A. I.
Published: July 2023

For the first time, a detailed comprehensive study of the "dry" etching of dislocation and dislocation-free germanium samples on the {111}, {110} and {100} planes has been carried out. Etching was carried out by exposure to pulses of nanosecond UV laser radiation of subthreshold intensity (wavelength 355 nm, duration ~ 10 ns, energy density ~ 0.5–1.3 J/cm2, pulse repetition rate 100 Hz, divergence 1–2 mrad). Before and after laser heat treatment of the surface, the samples were examined using a Zygo optical profilometer and a scanning electron microscope. Features of the nature of damage to surfaces corresponding to different crystallographic planes of single crystals of industrial dislocation germanium are revealed. They are compared with data on subthreshold damages of typical dislocation-free crystals.

It is shown that in dislocation samples of germanium on the {111} plane, it is possible to create a regime of exposure to radiation, leading to the formation of etch pits that are outwardly identical to dislocation pits detected during selective chemical etching. Their concentration corresponds in order of magnitude to the density of dislocations.

On the {100} plane of dislocation samples, etching results were also found, which clearly have a crystallographic nature. At an energy density of the acting radiation ≥ 0.4 J/cm2, on the surfaces of dislocation ({100} plane) and dislocation-free germanium ({111}, {100}, {110} planes), only individual spots ~ 50 μm in size were registered, as well as individual microcraters ~ 0.1–1 μm in size, which do not have crystallographic features. The possibility of environmentally friendly detection of dislocations in germanium without the use of chemical reagents is shown.
Sugammadex: A Milestone that Brings Changes in Anesthesia Practice
Authors:   Tawam Hospital, Tawam, Abu Dhabi, UAE, Modi Girishkumar , Kumar Vijay ,   Tawam Hospital, Tawam, Abu Dhabi, UAE, Munagala Nagaraju ,   Tawam Hospital, Tawam, Abu Dhabi, UAE
Published: July 2023

Sugammadex is a modified form of gamma-cyclodextrin that reverses the effects of rocuronium and vecuronium, which are aminosteroid non-depolarizing muscle relaxants (NDMR). It is the first and only reversal agent in the class of selective relaxant binding agents (SRBA) that reverses any depth of neuromuscular blockade without the unwanted muscarinic side effects of neostigmine (bronchospasm, nausea, vomiting, bradycardia, diarrhea, etc.) and anti-muscarinic side effects of glycopyrrolate (dry mouth, palpitations, urinary retention, constipation, etc.). It is an Food and Drug Administration (FDA)-approved agent that is safe for the reversal of neuromuscular block (NMB) caused by rocuronium and is available worldwide. Sugammadex practical use is predicted to alleviate many of the faults in present anesthetic practice regarding the antagonistic effects of rocuronium and other aminosteroid muscle relaxants. Despite being a novel agent in the reversal of NMB, the cost of sugammadex may limit its use as a regular antagonist of neuromuscular-blocking drugs.
SNARE-seq2 with Nuclei Hashing v1
Authors: Plongthongkum Nongluk
Published: July 2023

To study the heterogeneity of complex tissues by joint profiling of gene expression and its regulation, we require an accurate and high-throughput method. Here we described improved high-throughput combinatorial indexing-based single-nucleus chromatin accessibility and mRNA expression sequencing 2 (SNARE-Seq2) co-assay. This protocol involves fixing and permeabilizing the nucleus followed by tagmentation, chromatin barcode ligation, reverse transcription, pooling and splitting for the next rounds of cell barcode ligation into cDNA and accessible chromatin (AC) on the same nucleus. The captured cDNA and AC are co-amplified before splitting and enrichment into single-nucleus RNA and single-nucleus AC sequencing libraries. The protocol can also be applied to both nuclei and whole cells to capture mRNA in the cytoplasm. This improvement allows us to generate hundreds of thousands of data set of each assay and can be scaled up to half a million cells from a single experiment. The entire procedure can be complete in 3.5 d for generating joint single-nucleus RNA and single-nucleus ATAC sequencing libraries.
Most Probable Number Fluorescence Microplate Assay v1
Authors: Franco Meléndez Karla
Published: July 2023

Here we provide a step-by-step protocol for running the MPN fluorescence microplate assay with soil samples inoculated with a fluorescently tagged pathogen. We performed the MPN fluorescence assay in 96-well microplates to facilitate automation of fluorescence data collection using a plate reader. Serial dilutions were performed in semi-selective media and in the presence of a homoserine lactone to induce expression of a red fluorescent protein. When the signal is a product of the organism, rather than the medium, it reflects both viability and specificity simultaneously. For brevity, we refer to this method as the MPN-RFU microplate assay.
Detection of Leptospira wolffii in Water and Soil on Livestock Farms in Kelantan After a Massive Flood
Authors: Abdul Rahman Mohammad Sabri , Bejo Siti Khairani , Zakaria Zunita , Hassan Latiffah , Roslan Mohd Azri
Published: July 2023

Pathogenic leptospires cause leptospirosis in both animals and humans around the world. Humans can be infected by leptospires through direct contact with infected animals or indirect contact with leptospires contaminated water or soil. Outbreaks of leptospirosis usually occur after heavy rainfall and flooding, particularly in endemic areas. The aim of this study was to detect the presence of leptospires in water and soil in livestock farms after a massive flood in Kelantan. Samples were collected from 28 livestock farms in Kelantan, comprising 62 water samples and 62 soil samples, respectively. The samples were filtered and inoculated into a semisolid EMJH medium containing 5-FU for the isolation of Leptospira spp. The Leptospira spp. isolates were then identified using classical methods (1M NaCl, 8-azaguanine, and 13 °C), serology (MAT), multiplex polymerase chain reaction (mPCR), and DNA sequencing. The classical identification methods showed varying results and failed to differentiate between pathogenic and non-pathogenic leptospires. MAT showed the isolates reactions against serovars Autumnalis, Hebdomadis, Pyrogenes, Bataviae, Patoc, and Wolffii. However, mPCR showed that all isolates were non-pathogenic Leptospira spp. Further identification using DNA sequencing found that all isolates were identified as Leptospira wolffii, an intermediate species of Leptospira. The presence of L. wolffii in water and soil provides evidence that this species is circulating in the environment and could potentially transmit to humans and animals.
Identifying Multiple Outliers in Linear Functional Relationship Model using a Robust Clustering Method
Authors: Abdul Ghapor Adilah , Zubairi Yong Zulina , Md. Al Mamun Sayed , Hassan Siti Fatimah , Aruchunan Elayaraja , Mokhtar Nurkhairany Amyra
Published: July 2023

Outliers are some observation points outside the usual pattern of the other observations. It is essential to detect outliers as anomalous observations can affect the inference made in the analysis. In this study, we propose an efficient clustering procedure to identify multiple outliers in the linear functional relationship model using the single linkage algorithm with the Euclidean distance as the similarity measure. A new robust cut-off point using the median and median absolute deviation for the tree heights to classify the potential outliers are proposed in this study. Experimental results from the simulation study suggest our proposed method is able to identify the presence of multiple outliers with very small probability of swamping and masking. Application in real data also shows that the proposed clustering method for this linear functional relationship model successfully detects the outliers, thus suggesting the method's practicality in real-world problems.
Siber Güvenlik Araştırmalarına Küresel Bir Bakış: Yayın Trendleri ve Araştırma Yönelimleri
Authors: KARAYEL Tuğçe , AKBIYIK Adem
Published: July 2023

Makale, Web of Science'ın veritabanında indekslenen siber güvenlik ve bilgi güvenliği araştırmalarının kapsamlı bir bibliyometrik analizini sunmaktadır. Siber güvenlik, son zamanların ilgi odağı olan popüler bir araştırma konusudur. Alandaki küresel araştırma verimliliğini ve gelişimini incelemek için 1980 ve 2021 yılları arasında yayınlanan 4252 makale R tabanlı Biblioshiny paket programı ile analiz edilmiştir. Siber güvenlik alanındaki yayınlanan araştırmalar yıllara göre giderek artan bir eğilim gösterirken bilgi güvenliği ile ilgili olan yayınlar giderek azalan bir eğim göstermiştir. Alanın kavramsal yapısı incelediğinde, son dönemin en dikkat çekici araştırma konuları “siber güvenlik farkındalığı” ve “siber fiziksel sistemler” olduğu bulunmuştur. Ek olarak alanın tematik ağ haritası incelendiğinde, bilgi güvenliği alanının sosyal boyutunu ifade eden bilgi güvenliği farkındalığı, bilgi güvenliği yönetimi, bilgi güvenliği politikaları, bilgi güvenliği kültürü gibi konularla daha çok çalışılmıştır. Siber güvenlik alanının teknik tarafını ifade eden yapay zeka, büyük veri, blokzincir, makine öğrenmesi ve derin öğrenme gibi konularla daha çok çalışıldığı ortaya çıkmıştır. Çalışmanın bulguları, araştırmacılara, bilgi teknolojisi uzmanlarına ve bilgi uzmanlarına, siber güvenlik alanındaki araştırma ilerlemesine ve yeni araştırma konularını belirlemede yardımcı olabileceği ön görülmektedir.
Policy of President Joe Biden’s administration towards creation an anti-iranian alliance in the Middle East
Authors:   The State institution «Institute of World History of NAS of Ukraine», Kyiv, Ukraine, Shved Viacheslav
Published: July 2023

The article deals with the foreign course of President Joe Biden’s administration in regard to making an anti-iranian coalition in the Middle East. Due to a plethora of intra and extra factors, this particular deal has become crucial. The significance is defined by analyzing one of the most important aspects of American foreign policy in the Middle East for the last short period of time. Its realization will help not only oppose Iranian expansionism in the region but also stand against a possible alliance of two dictators regimes – Putin’s and Ayatollahs’ – in the Russian-Ukrainian war, and in the future could lead to serious danger for all regional security system in the Middle East. The aim of the article is to systematic investigation of the US’ foreign strategy to create an anti-Iranian alliance in the Middle East, mentioning new features, that occur from late 2022 and the beginning of 2023. The article shows the importance of the anti-Iranian alliance as one of the pivotal fronts of war between the global democratic team led by the US and the global dictators’ bunch, which can possibly doom the future of humanity. Methods include a broad mix of general scientific and narrow methods like systemic method, comparative analysis, sources’ critic analysis. The scientific novelty of the research lies in the fact that the author is first in Ukrainian historiography, who tried to investigate the ongoing process of reforming the political and security situation in the Middle East and made a complex analysis of one of the top priority foreign policy themes, conducted by President Joe Biden’s administration in the Middle East, with inventing into research agenda new American, Israel and Arab sources. New reasons and facets in the Middle Eastern geopolitical situation are highlighted, which indicate the cruciality of the research problem. The author draws a conclusion about the correlation of processes in the Middle East and Ukraine, in particular, that the policy of J. Biden’s administration in the specified direction allows more effective resistance to Russian aggression in Ukraine.
Synthesis of an adaptive observer of the resistance torque at a shaft of a traction electric motor
Authors: Klimov Aleksandr V.
Published: July 2023

BACKGROUND: Operating companies and consumers have demands to vehicles for efficiency improvement and cost cut. A part of substantial expenses is fuel cost, therefore use of vehicles with electric drive such as hybrid or pure electric (battery-electric) has potential for agriculture. It is mainly important for them to have the drivetrain characterized by high efficiency that increases autonomous mileage for one charge. To achieve this, it is necessary to control electric motors in the way to ensure maximal surface grip coefficient without wheel slipping. In this case, real-time defining of wheel resistance torque in necessary for efficient control.
AIMS: Development of the theoretical basis and the law of optimal estimation of the resistance torque at a shaft of traction electric motor of transport vehicles for the sake of efficient control of traction electric drive.
METHODS: Simulation of the law of optimal estimation of the resistance torque at a shaft of traction electric motor was carried out in the MATLAB/Simulink software package.
RESULTS: The article provides with theoretical basis of formatting the law of optimal estimation of the resistance torque at a shaft of traction electric motor of transport vehicles for the sake of efficient control of traction electric drive, the law of optimal estimation of the resistance torque at a shaft of traction electric motor and the results of simulation of the law of optimal estimation of the resistance torque at a shaft of traction electric motor obtained in the MATLAB/Simulink.
CONCLUSIONS: Practical value of the study lies in ability of using the proposed control laws for development of transport vehicles drivetrain control system.
Increase in performance of air-sieve grain-cleaning machines in separating heap of sunflower seeds
Authors: Priporov Igor E.
Published: July 2023

BACKGROUND: The performance of grain cleaning machines (GCM) of the air-sieve type and the quality of grain cleaning depend on the uniformity of the loading of the sieves, which is determined by the design of the supply-distribution device. A decrease in the inclination angle of the feeding device surface leads to a decrease in the intensity of supply of the heap closer to the axis, further reduction leads the heap to stop in this area. Therefore, the inclination angle reduction for the feeding device is below the friction coefficient that leads to a decrease in the loading distribution uniformity. AIMS: Determination the dependence of the sorting process parameter of a heap of sunflower seeds on the material for the feeding device surface in the MVU-1500 air-sieve GCM. METHODS: To determine the inclination angle of the feeding device in the process of sorting the Lakomka variety sunflower seeds, which affects the parameters of the pneumatic system of the MVU-1500 air-sieve GCM, an experimental installation was built to determine the heap movement velocity. The used methods were a privately developed methodology, methods of mathematical statistics and laws of theoretical mechanics. RESULTS: The movement velocity of the heap of sunflower seeds on the surface of the feeding device were considered. Using the feeding device, the experimental and theoretical movement velocities of the heap of sunflower seeds on its surface made of metal and fluoropolymer included in the standard and improved MVU-1500 air-sieve GCMs were determined. CONCLUSIONS: The practical value of the study lies in determining the theoretical movement velocity of the heap of sunflower seeds on the GCMs feeding device surface which depends on its inclination angle as well as on the optimal material for it.
Intracellular level of HIF-1α as an indicator of the delayed impact of COVID-19 on peripheral blood lymphocytes metabolism
Authors: Zubatkina Olga V. , Dobrodeeva Lilia K. , Kruglov Sergey D.
Published: July 2023

BACKGROUND: COVID-19 infection triggers metabolic alterations that are crucial for both the replication of SARS-CoV-2 and the regulation of the immune response. HIF-1, which is one of the effectors in the PI3K/Akt/mTOR signal transmission pathway, promotes the reprogramming of metabolism by enhancing aerobic glycolysis.
AIM: To assess whether the intracellular level of HIF-1 can reflect changes in the metabolism of peripheral blood lymphocytes after a COVID-19 infection.
MATERIAL AND METHODS: The sample consisted of 59 volunteers. Thirty eight of them had no history of COVID-19 while 21 reported having COVID-19 infection 28 months prior to the study. Serum concentrations of IgG antibodies to SARS-CoV-2 were assessed in both groups. Absolute content of lymphocytes was measured in whole blood, and the concentration of HIF-1 was determined in the lymphocyte lysate by enzyme immunoassay. All data were analyzed using IBM SPSS software (v. 26). Means and standard deviations were calculated for all numeric variables. Normality of the distributions were assessed using KolmogorovSmirnov test. Differences between the groups were studied by unpaired Student's t-tests. The differences at p 0.05 were considered statistically significant. Receiver operative characteristic curve was constructed to assess the prognostic value of HIF-1.
RESULTS: Volunteers with a history of COVID-19 infection had significantly lower concentrations of HIF-1 in peripheral blood lymphocytes compared to their counterparts with no history of COVID-19. Intracellular concentration of HIF-1 was significantly associated with the likelihood of changes in lymphocyte metabolism. HIF-1 concentration of 1.25 ng/106 cells was the most optimal cut-off value.
CONCLUSION: The intracellular level of HIF-1 can serve as an indicator of the potential delayed impact of COVID-19 on the metabolic activity of peripheral lymphocytes. Our research findings hold significant value in monitoring and assessing metabolic alterations in individuals recovering from COVID-19.
Girate atrophy: clinical and functional features
Authors: Kogoleva Ludmila V. , Zolnikova Inna V. , Kokoeva Nina Sh. , Bobrovskaya Julia A. , Milash Sergey V.
Published: July 2023

Gyrate atrophy is a rare genetic metabolic disease with an autosomal recessive inheritance that causes progressive chorioretinal atrophy, fundus manifestations, and decreased visual function. The prognosis of the disease largely depends on the development and progression of complications (macular changes and cataracts) as well as concomitant neurological and somatic pathology.
AIM: To describe three clinical cases of hypertension.
MATERIAL AND METHODS: We examined three children with gyrate atrophy at 4, 10, and 15 years old. All patients underwent a comprehensive ophthalmological examination, including modern diagnostics, visualization, and electrophysiological studies.
RESULTS: Although older patients have more pronounced changes in the fundus with involvement of the macular zone in the pathological process, a 4-year-old child has pronounced functional retinal disorders detected during electroretinogram registration, indicating an earlier manifestation of the pathological process. Gyrate atrophy was combined with foveoschisis and ornithinemia in older patients (10 and 15 years old).
The differential diagnosis of gyrate atrophy should be carried out with high myopia with areas of dystrophy of the cobblestone pavement type on the periphery of the fundus, resembling foci of chorioretinal changes in hypertension.
CONCLUSION: Patients with gyrate atrophy require an interdisciplinary approach that includes not only ophthalmologists but also pediatricians, medical geneticists, and other specialists with comorbidities.
Innovation for All: Unleashing the Power of Assistive Technology in Special Education in Arabic-Speaking Countries
Authors: Alanazi Mona Saleh
Published: July 2023

This topical review digs into special education teachers' growing usage of Assistive Technology (AT) in Arabic-speaking countries to serve children with impairments. This study investigates AT's benefits, drawbacks, and possible applications in this educational setting by reviewing the available literature from six major academic databases, including Scopus, Web of Science, JSTOR, ERIC, Academia, and ResearchGate. The findings highlight the need for tailored and student-centered approaches to AT adoption and effective training and ongoing support for educators and students. Furthermore, the study emphasizes the potential of AT to improve academic and functional outcomes, allowing students to overcome obstacles and actively participate in their educational path. The significance of these findings for future special education research and practice is examined, laying the groundwork for further investigation of AT's influence on children with disabilities in Arabic-speaking countries. The outcomes of this review emphasize the need to implement AT in Arabic-speaking special education settings using tailored and student-centered approaches. Students with disabilities can effectively use AT solutions to enhance their learning experiences by tailoring AT solutions to specific needs. Furthermore, the study emphasizes the importance of instructor and student training and ongoing assistance. Proper training provides instructors with the skills and information they need to properly deploy AT tools, while continual support ensures that AT remains effective in the classroom.
Peran Internet Sebagai Inti Penting di Society 5.0
Authors: Nabil Hidayat Muhamad Farik , Wibawa Aji
Published: July 2023

The development of digitalization that has occurred in almost all populations around the world has created an active and creative society in all fields. Society 5.0 encourages towards a previously unimaginable reality. In this era, it is possible to develop various sectors to support the formation of an intelligent society. This research results in the role of the internet in various fields to support a more comfortable world for the entire global population. The purpose of this research is to guide society as problem solvers in the evolution of the world in Society 5.0. In addition, there are methods and analysis techniques applied in this paper, so that the research produced is beneficial for society. Some findings in this research are that the internet is the core of Society 5.0 and that society plays an important role in utilizing technology to create an intelligent society and a comfortable world to live in. This research concludes that society must utilize the ability of the internet and media created in Society 5.0 because these three aspects are interconnected to create reality.

Perkembangan digitalisasi yang terjadi hampir semua populasi di seluruh dunia ini, menciptakan masyarakat yang aktif dan kreatif dalam semua bidang.  Society 5.0 mendorong menuju realita yang sebelumnya bahkan tidak terpikirkan dapat direalisasikan. Di era ini memungkinkan pengembangan pada berbagai sektor untuk menunjang pembentukan masyarakat yang cerdas. Penelitian ini menghasilkan peran internet dalam berbagai bidang untuk menunjang dunia yang lebih nyaman bagi seluruh populasi dunia. Tujuan dari riset ini bermaksud untuk menuntun masyarakat sebagai pemecah masalah dalam evolusi dunia di society 5.0. Disamping itu, terdapat metode dan teknik analisis yang diterapkan dalam paper ini, agar paper yang dibuat peneliti bermanfaat bagi masyarakat. Beberapa temuan dalam riset ini adalah internet sebagai inti di society 5.0 dan masyarakat memiliki peran penting dalam pemanfaatan teknologi guna menciptakan masyarakat yang cerdas dan dunia yang nyaman untuk dihuni. Penelitian ini menghasilkan kesimpulan bahwa masyarakat harus memanfaatkan kemampuan dari internet serta media-media yang sudah tercipta di society 5.0 karena ketiga hal tersebut saling berhubungan agar terciptanya realitas.
Abordaje clínico en usuarios con terapia conductual cognitiva
Authors: Chirio Aldazabal Diego Bernardo
Published: July 2023

El profesional en psicología que se desenvuelve en ámbitos aplicados, debe de recurrir a las corrientes de conocimientos que se encuentran dentro de aquello a lo que denominamos psicología, todo esto para potenciar el alcance de sus objetivos en la práctica clínica, los cuales son denominados como terapéuticos. El presente trabajo tiene como propósito desarrollar una revisión sobre el abordaje clínico en usuarios con terapia conductual-cognitiva. Se considera la ausencia de un cuerpo de conocimiento unificado y se incentiva a no contentarse con solo un aporte, sino complementarlo con otros, como si se tratara de completar un rompecabezas (metafóricamente). Se enfatiza en la necesidad de conocimiento sobre teorías del aprendizaje, propuestas de formulación del caso y revisión de estudios sobre el apoyo empírico de diferentes estrategias terapéuticas. Se concluye que tanto las estrategias conductuales como cognitivas permiten contar no solo con una serie de procedimientos, sino marcos de referencia para poder interpretar los acontecimientos especifico-circunstanciales que el profesional en psicología se encuentra a diario.
El dispositivo dialógico. Límites de lo decible en las disputas memoriales en Argentina
Authors: Salvi Valentina
Published: July 2023

Actualmente en Argentina, diversas voces provenientes de los familiares de los militares condenados por crímenes de lesa humanidad y del arco político de derecha convergen en posturas críticas a las memorias sobre el terrorismo de Estado, las políticas de justicia y reparación implementadas durante los gobiernos kirchneristas (2003-2015) y la actuación de los organismos de derechos humanos. En este contexto de fuerte polarización política, el dispositivo memorial del diálogo, de creciente circulación internacional, se presentó en el escenario de disputas por la memoria como una forma aggiornada de la gestión del pasado reciente como alternativo a la justicia. Este artículo se propone analizar el dispositivo del diálogo como modo de “enunciación” o “de hacer ver y hacer hablar” sobre el pasado, haciendo foco en las condiciones simbólicas y políticas que regulan estos intercambios dialógicos y en los efectos de sentido que provocan en las memorias sobre el pasado dictatorial.
Особенности личности креативов
Authors: Кряжева К.Л
Published: July 2023

В статье рассмотрена роль креативности. Выделены понятие, содержание креативности как одного из важных компонентов творческой личности. Определены методологические основы, условия и основные направления исследований творческого развития. Показана специфика различий между креативностью, творчеством и интеллектом
Зависимость течения и прогноза полинейропатии от тяжести осложнений сахарного диабета второго типа
Authors: Ахметжанова А.Р. , Исабаева А.И. , Зерчанинова Е.И , Маклакова И.Ю
Published: July 2023

Сахарный диабет – одно из самых распространенных неинфекционных заболеваний нашего времени, которое может приводить к серьезным осложнениям различных органов и тканей, в том числе и неврологическим. Например, осложнения могут быть связаны с поражением периферической нервной системы в виде диабетической полинейропатии (ДПН), фактором развития которой является хроническая гипергликемия, приводящая к нарушению функции микроциркулярных сосудов и периферических нервных волокон.
Анализ динамики показателей тропонина Т и креатинфосфокиназы МВ до и после лечения у больных с острым инфарктом миокарда.
Authors: Демина Т.Ю , Шевченко М.О , Зерчанинова Е.И , Капралов А.И
Published: July 2023

В статье рассматривается изменение показателей тропонина Т и КФК-МВ до и после лечения у больных с острым инфарктом миокарда. Проведено ретроспективное исследование с применением метода статистического анализа.
Вопросы гериатрии в работе врача общей практики
Authors: Матюшков П.И , Мамытбекова Д.З , Усубалиев М.Б , Дворкин М.И , Станбаева Б.О
Published: July 2023

В статье обсуждаются вопросы рационального ведения больных пожилого и старческого возраста с учетом особенностей данного контингента. Подчеркиваются важность интегрального подхода к пожилому пациенту, а также необходимость широкой общеклинической подготовки курирующего врача, его осведомленности и практической ориентации в различных смежных клинических дисциплинах. Основной акцент в лечебно-профилактической помощи пожилым должен быть сделан на внебольничных формах ведения больных.
Этиологические и эпидемиологические особенности вентилятор-ассоциированной пневмонии в отдельно взятой реанимации
Authors: Румянцев А.Л , Рыбалко М.С , Поляков Е.А , Румянцева Е.В.
Published: July 2023

В статье описаны результаты проведенного исследования, целью которого было определить частоту встречаемости вентилятор-ассоциированной пневмонии среди пациентов, подверженных ИВЛ в травматологической и нейрохирургической реанимации, определить факторы риска, а также спектр возбудителей, и насколько обнаруженный спектр соотносится с данными AMRmap. В работе использовались данные историй болезни пациентов «ОГБУЗ КБСМП города Смоленска» отделения Анестезиологии-реаниматологии № 2. Анализ показал, распространенность вентилятор-ассоциированной пневмонии относительно невысока (7%). Тяжесть основного процесса в совокупности с длительностью вентиляции с присоединением ВАП приводит к существенному повышению летальности.
Влияние избыточного питания и ожирения на фолликулогенез
Authors: Хрипченко А.Д.
Published: July 2023

По данным ВОЗ каждый десятый человек страдает расстройством пищевого поведения. К сожалению, лишь 23% опрошенных студентов высших учебных заведения города Воронежа считают своѐ питание рациональным. Многие употребляют избыточное количество углеводной пищи. Избыток углеводов в рационе может привести к ожирению. Это обуславливает актуальность изучения влияния избыточного питания и ожирения на физиологию репродуктивной системы женщин. В данной статье описано влияние избыточного питания и ожирения на фолликулогенез.
Связь между правильным питанием и получением наилучших результатов в спорте
Authors: Габдриев Б.А , Севодин С.В
Published: July 2023

Статья рассматривает важность правильного питания для достижения высоких спортивных результатов. В работе исследуются теоретические аспекты связи между питанием и спортом, исследования влияния питания на показатели спортивной формы, а также оценка влияния типа спортивной активности на питание. В статье приводятся рекомендации по употреблению питательных веществ в зависимости от вида спорта, а также анализируются проблемы, связанные с питанием спортсменов
Менеджмент в спорте
Authors: Айвазова Е.С , Савельева В.В.
Published: July 2023

Статья посвящена определению «менеджмента в спорте», его целям и значимости в спортивном сообществе, функционированию с учетом рыночных условий. Авторы подчеркнули уникальные черты менеджмента в спортивной сфере и его взаимосвязь с другими аспектами работы в физкультурно-спортивной области.
Адаптация организма к физическим нагрузкам, компенсаторные и приспособительные реакции организма
Authors: Амбарцумян В.Э. , Винничек А.С. , Захарченко А.Е.
Published: July 2023

В данной статье рассматривается тема "Адаптация организма к физическим нагрузкам, компенсаторные и приспособительные реакции организма". Авторы обсуждают механизмы адаптации организма к физической активности и стрессу. В частности, рассматриваются компенсаторные реакции организма на физическую нагрузку, такие как увеличение сердечного ритма и дыхательной частоты. Также обсуждаются приспособительные реакции, которые проявляются в улучшении функциональной способности организма при повторяемых тренировках или других формах физической активности.
Проблемы организации занятий физической культурой со студентами, имеющими отклонения в состоянии здоровья
Authors: Аникеева Н.Г.
Published: July 2023

Введение: Трудности в экономической, социальной, экологической сферах российской жизни выдвинули ряд проблем перед социальными институтами, в том числе и перед системой профессионального образования. Одна из них связана с приобщением студенческой молодежи к культуре физической, той самой культуре, без овладения основами которой жизнь и работа будут не полноценными. Здоровье - самая большая ценность, стремление его сохранить, должно занимать главное место среди прочих потребностей человека. В современных условиях здоровье человека рассматривается как мощный фактор повышения своего социального статуса, оптимальной трудоспособности и продолжительности жизни, а также обеспечения безопасности страны, повышения ее технико-экономического потенциала. Исследования проводились на базе ГАУ «Северного Зауралья», 2021 – 2022 учебный год, со студентами специального-медицинского отделения. Сложившаяся ситуация является следствием не только неблагоприятных социальных факторов, но прежде всего физической и функциональной детренированностью, обусловленной снижением двигательной активности молодежи, а также не совершенством методологической базы для занятий физической культурой для студентов с заболеваниями, в системе вузовского образования.
Влияние физических нагрузок на эмоциональное состояние студента
Authors: Гаджиев Р.М. , Шульга В.В.
Published: July 2023

В данной статье исследуется влияние физических нагрузок на внутреннее состояние студентов и их нервную систему.Рассмотрено понятие утомление и фазы утомления, а также средства восстановления организма организма после утомления. В статье проведено исследование психологических областей физически подготовленных и неподготовленных людей. Затронута тема влияния физических нагрузок напсихофизиологическое состояние студентов.