bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Tables and Figure Legends_Unmarked from A Phase I/II Study of Neoadjuvant Cisplatin, Docetaxel, and Nintedanib for Resectable Non–Small Cell Lung Cancer
Authors: Cascone Tina , Sepesi Boris , Lin Heather Y. , Kalhor Neda , Parra Edwin R. , Jiang Mei , Godoy Myrna C.B. , Zhang Jianjun , Fossella Frank V. , Tsao Anne S. , Lam Vincent K. , Lu Charles , Mott Frank E. , Simon George R. , Antonoff Mara B. , Mehran Reza J. , Rice David C. , Behrens Carmen , Weissferdt Annikka , Moran Cesar , Vaporciyan Ara A. , Lee J. Jack , Swisher Stephen G. , Gibbons Don L. , Wistuba Ignacio I. , William William N. , Heymach John V.
Published: April 2023

Supplementary Tables and Figure Legends_Unmarked
Supplementary Figure 2 from A Phase I/II Study of Neoadjuvant Cisplatin, Docetaxel, and Nintedanib for Resectable Non–Small Cell Lung Cancer
Authors: Cascone Tina , Sepesi Boris , Lin Heather Y. , Kalhor Neda , Parra Edwin R. , Jiang Mei , Godoy Myrna C.B. , Zhang Jianjun , Fossella Frank V. , Tsao Anne S. , Lam Vincent K. , Lu Charles , Mott Frank E. , Simon George R. , Antonoff Mara B. , Mehran Reza J. , Rice David C. , Behrens Carmen , Weissferdt Annikka , Moran Cesar , Vaporciyan Ara A. , Lee J. Jack , Swisher Stephen G. , Gibbons Don L. , Wistuba Ignacio I. , William William N. , Heymach John V.
Published: April 2023

Supplementary Figure 2
Supplementary Figure 2 from Glioblastoma-mediated Immune Dysfunction Limits CMV-specific T Cells and Therapeutic Responses: Results from a Phase I/II Trial
Authors: Weathers Shiao-Pei , Penas-Prado Marta , Pei Be-Lian , Ling Xiaoyang , Kassab Cynthia , Banerjee Pinaki , Bdiwi Mustafa , Shaim Hila , Alsuliman Abdullah , Shanley Mayra , de Groot John F. , O'Brien Barbara J. , Harrison Rebecca , Majd Nazanin , Kamiya-Matsuoka Carlos , Fuller Gregory N. , Huse Jason T. , Chi Linda , Rao Ganesh , Weinberg Jeffrey S. , Lang Frederick F. , Sawaya Raymond , Shpall Elizabeth J. , Rezvani Katayoun , Heimberger Amy B.
Published: April 2023

Supplementary Figure 2
Figure 1S from Results of the ADAPT Phase 3 Study of Rocapuldencel-T in Combination with Sunitinib as First-Line Therapy in Patients with Metastatic Renal Cell Carcinoma
Authors: Figlin Robert A. , Tannir Nizar M. , Uzzo Robert G. , Tykodi Scott S. , Chen David Y.T. , Master Viraj , Kapoor Anil , Vaena Daniel , Lowrance William , Bratslavsky Gennady , DeBenedette Mark , Gamble Alicia , Plachco Ana , Norris Marcus S. , Horvatinovich Joe , Tcherepanova Irina Y. , Nicolette Charles A. , Wood Christopher G.
Published: April 2023

Consort diagram
Supplementary Methods, Figures S1-14 from Dual Targeting of CDK4/6 and BCL2 Pathways Augments Tumor Response in Estrogen Receptor–Positive Breast Cancer
Authors: Whittle James R. , Vaillant François , Surgenor Elliot , Policheni Antonia N. , Giner Göknur , Capaldo Bianca D. , Chen Huei-Rong , Liu He K. , Dekkers Johanna F. , Sachs Norman , Clevers Hans , Fellowes Andrew , Green Thomas , Xu Huiling , Fox Stephen B. , Herold Marco J. , Smyth Gordon K. , Gray Daniel H.D. , Visvader Jane E. , Lindeman Geoffrey J.
Published: April 2023

Supplemental Methods and Figures
Supplementary Legends from Comprehensive Genomic Analysis of Translocation Renal Cell Carcinoma Reveals Copy-Number Variations as Drivers of Disease Progression
Authors: Marcon Julian , DiNatale Renzo G. , Sanchez Alejandro , Kotecha Ritesh R. , Gupta Sounak , Kuo Fengshen , Makarov Vladimir , Sandhu Amar , Mano Roy , Silagy Andrew W. , Blum Kyle A. , Nassau Daniel E. , Benfante Nicole E. , Ortiz Michael V. , Carlo Maria I. , Chan Timothy A. , Motzer Robert J. , Voss Martin H. , Coleman Jonathan , Russo Paul , Reuter Victor , Hakimi A. Ari , Reznik Ed
Published: April 2023

Supplementary Legends
Supplementary Figure S2 from Identification of Somatically Acquired BRCA1/2 Mutations by cfDNA Analysis in Patients with Metastatic Breast Cancer
Authors: Vidula Neelima , Dubash Taronish , Lawrence Michael S. , Simoneau Antoine , Niemierko Andrzej , Blouch Erica , Nagy Becky , Roh Whijae , Chirn Brian , Reeves Brittany A. , Malvarosa Giuliana , Lennerz Jochen , Isakoff Steven J. , Juric Dejan , Micalizzi Douglas , Wander Seth , Spring Laura , Moy Beverly , Shannon Kristen , Younger Jerry , Lanman Richard , Toner Mehmet , Iafrate A. John , Getz Gad , Zou Lee , Ellisen Leif W. , Maheswaran Shyamala , Haber Daniel A. , Bardia Aditya
Published: April 2023

Survival curves
Supplementary Figure S1 from Identification of Somatically Acquired BRCA1/2 Mutations by cfDNA Analysis in Patients with Metastatic Breast Cancer
Authors: Vidula Neelima , Dubash Taronish , Lawrence Michael S. , Simoneau Antoine , Niemierko Andrzej , Blouch Erica , Nagy Becky , Roh Whijae , Chirn Brian , Reeves Brittany A. , Malvarosa Giuliana , Lennerz Jochen , Isakoff Steven J. , Juric Dejan , Micalizzi Douglas , Wander Seth , Spring Laura , Moy Beverly , Shannon Kristen , Younger Jerry , Lanman Richard , Toner Mehmet , Iafrate A. John , Getz Gad , Zou Lee , Ellisen Leif W. , Maheswaran Shyamala , Haber Daniel A. , Bardia Aditya
Published: April 2023

Consort diagram.
Supplementary figure legends from Regulation of eIF4F Translation Initiation Complex by the Peptidyl Prolyl Isomerase FKBP7 in Taxane-resistant Prostate Cancer
Authors: Garrido Marine F. , Martin Nicolas J.-P. , Bertrand Matthieu , Gaudin Catherine , Commo Frédéric , El Kalaany Nassif , Al Nakouzi Nader , Fazli Ladan , Del Nery Elaine , Camonis Jacques , Perez Franck , Lerondel Stéphanie , Le Pape Alain , Compagno Daniel , Gleave Martin , Loriot Yohann , Désaubry Laurent , Vagner Stéphan , Fizazi Karim , Chauchereau Anne
Published: April 2023

Supplementary figure legends
Figure S7 from Regulation of eIF4F Translation Initiation Complex by the Peptidyl Prolyl Isomerase FKBP7 in Taxane-resistant Prostate Cancer
Authors: Garrido Marine F. , Martin Nicolas J.-P. , Bertrand Matthieu , Gaudin Catherine , Commo Frédéric , El Kalaany Nassif , Al Nakouzi Nader , Fazli Ladan , Del Nery Elaine , Camonis Jacques , Perez Franck , Lerondel Stéphanie , Le Pape Alain , Compagno Daniel , Gleave Martin , Loriot Yohann , Désaubry Laurent , Vagner Stéphan , Fizazi Karim , Chauchereau Anne
Published: April 2023

Targeting eIF4F complex in chemoresistant cells
Supplementary Data from Drugs That Modify Cholesterol Metabolism Alter the p38/JNK-Mediated Targeted and Nontargeted Response to Alpha and Auger Radioimmunotherapy
Authors: Ladjohounlou Riad , Lozza Catherine , Pichard Alexandre , Constanzo Julie , Karam Jihad , Le Fur Pierre , Deshayes Emmanuel , Boudousq Vincent , Paillas Salomé , Busson Muriel , Le Blay Marion , Jarlier Marta , Marcatili Sara , Bardiès Manuel , Bruchertseifer Frank , Morgenstern Alfred , Torgue Julien , Navarro-Teulon Isabelle , Pouget Jean-Pierre
Published: April 2023

Supplementary Figure legend
Figure S6 from Regulation of eIF4F Translation Initiation Complex by the Peptidyl Prolyl Isomerase FKBP7 in Taxane-resistant Prostate Cancer
Authors: Garrido Marine F. , Martin Nicolas J.-P. , Bertrand Matthieu , Gaudin Catherine , Commo Frédéric , El Kalaany Nassif , Al Nakouzi Nader , Fazli Ladan , Del Nery Elaine , Camonis Jacques , Perez Franck , Lerondel Stéphanie , Le Pape Alain , Compagno Daniel , Gleave Martin , Loriot Yohann , Désaubry Laurent , Vagner Stéphan , Fizazi Karim , Chauchereau Anne
Published: April 2023

Interaction of FKBP7 with eIF4G
Figure S4 from Regulation of eIF4F Translation Initiation Complex by the Peptidyl Prolyl Isomerase FKBP7 in Taxane-resistant Prostate Cancer
Authors: Garrido Marine F. , Martin Nicolas J.-P. , Bertrand Matthieu , Gaudin Catherine , Commo Frédéric , El Kalaany Nassif , Al Nakouzi Nader , Fazli Ladan , Del Nery Elaine , Camonis Jacques , Perez Franck , Lerondel Stéphanie , Le Pape Alain , Compagno Daniel , Gleave Martin , Loriot Yohann , Désaubry Laurent , Vagner Stéphan , Fizazi Karim , Chauchereau Anne
Published: April 2023

Chemoresistant mouse model
Figure S7 from Drugs That Modify Cholesterol Metabolism Alter the p38/JNK-Mediated Targeted and Nontargeted Response to Alpha and Auger Radioimmunotherapy
Authors: Ladjohounlou Riad , Lozza Catherine , Pichard Alexandre , Constanzo Julie , Karam Jihad , Le Fur Pierre , Deshayes Emmanuel , Boudousq Vincent , Paillas Salomé , Busson Muriel , Le Blay Marion , Jarlier Marta , Marcatili Sara , Bardiès Manuel , Bruchertseifer Frank , Morgenstern Alfred , Torgue Julien , Navarro-Teulon Isabelle , Pouget Jean-Pierre
Published: April 2023

SUPPLEMENTARY FIG. S7. Oxidative stress proteins activated in SK-OV-3MISRII and HCT116 cells after RIT.
Supplementary Data S1 from Integrative Analysis of Multi-omics Data Identified EGFR and PTGS2 as Key Nodes in a Gene Regulatory Network Related to Immune Phenotypes in Head and Neck Cancer
Authors: Feng Bohai , Shen Ying , Pastor Hostench Xavier , Bieg Matthias , Plath Michaela , Ishaque Naveed , Eils Roland , Freier Kolja , Weichert Wilko , Zaoui Karim , Hess Jochen
Published: April 2023

Supplementary Data S1
Supplementary Data Legend from Enhancing Abiraterone Acetate Efficacy in Androgen Receptor–positive Triple-negative Breast Cancer: Chk1 as a Potential Target
Authors: Grellety Thomas , Callens Celine , Richard Elodie , Briaux Adrien , Vélasco Valérie , Pulido Marina , Gonçalves Anthony , Gestraud Pierre , MacGrogan Gaetan , Bonnefoi Hervé , Cardinaud Bruno
Published: April 2023

Supplementary data legend
Supplementary Data from A Phase II Study of Tumor-infiltrating Lymphocyte Therapy for Human Papillomavirus–associated Epithelial Cancers
Authors: Stevanović Sanja , Helman Sarah R. , Wunderlich John R. , Langhan Michelle M. , Doran Stacey L. , Kwong Mei Li M. , Somerville Robert P.T. , Klebanoff Christopher A. , Kammula Udai S. , Sherry Richard M. , Yang James C. , Rosenberg Steven A. , Hinrichs Christian S.
Published: April 2023

Text for data supplement
Supplementary Materials and Methods from Mutational Analysis Identifies Therapeutic Biomarkers in Inflammatory Bowel Disease–Associated Colorectal Cancers
Authors: Din Shahida , Wong Kim , Mueller Mike F. , Oniscu Anca , Hewinson James , Black Catherine J. , Miller Martin L. , Jiménez-Sánchez Alejandro , Rabbie Roy , Rashid Mamunar , Satsangi Jack , Adams David J. , Arends Mark J.
Published: April 2023

Supplementary Materials and Methods
Supplementary information from A Combinatorial Strategy for Targeting BRAFV600E-Mutant Cancers with BRAFV600E Inhibitor (PLX4720) and Tyrosine Kinase Inhibitor (Ponatinib)
Authors: Ghosh Chandrayee , Kumar Suresh , Kushchayeva Yevgeniya , Gaskins Kelli , Boufraqech Myriem , Wei Darmood , Gara Sudheer Kumar , Zhang Lisa , Zhang Ya-qin , Shen Min , Mukherjee Sanjit , Kebebew Electron
Published: April 2023

Supplementary method and data
Video 2 from Radiation with STAT3 Blockade Triggers Dendritic Cell–T cell Interactions in the Glioma Microenvironment and Therapeutic Efficacy
Authors: Ott Martina , Kassab Cynthia , Marisetty Anantha , Hashimoto Yuuri , Wei Jun , Zamler Daniel , Leu Jia-Shiun , Tomaszowski Karl-Heinz , Sabbagh Aria , Fang Dexing , Gupta Pravesh , Priebe Waldemar , Zielinski Rafal J. , Burks Jared K. , Long James P. , Kong Ling-Yuan , Fuller Gregory N. , DeGroot John , Sulman Erik P. , Heimberger Amy B.
Published: April 2023

Video 2
Video 1 from Radiation with STAT3 Blockade Triggers Dendritic Cell–T cell Interactions in the Glioma Microenvironment and Therapeutic Efficacy
Authors: Ott Martina , Kassab Cynthia , Marisetty Anantha , Hashimoto Yuuri , Wei Jun , Zamler Daniel , Leu Jia-Shiun , Tomaszowski Karl-Heinz , Sabbagh Aria , Fang Dexing , Gupta Pravesh , Priebe Waldemar , Zielinski Rafal J. , Burks Jared K. , Long James P. , Kong Ling-Yuan , Fuller Gregory N. , DeGroot John , Sulman Erik P. , Heimberger Amy B.
Published: April 2023

Video
Figure S7 from Radiation with STAT3 Blockade Triggers Dendritic Cell–T cell Interactions in the Glioma Microenvironment and Therapeutic Efficacy
Authors: Ott Martina , Kassab Cynthia , Marisetty Anantha , Hashimoto Yuuri , Wei Jun , Zamler Daniel , Leu Jia-Shiun , Tomaszowski Karl-Heinz , Sabbagh Aria , Fang Dexing , Gupta Pravesh , Priebe Waldemar , Zielinski Rafal J. , Burks Jared K. , Long James P. , Kong Ling-Yuan , Fuller Gregory N. , DeGroot John , Sulman Erik P. , Heimberger Amy B.
Published: April 2023

Figure S7 shows a whole brain coronal section of GL261 tumor bearing brain stained for CD11c+ and CD3+.
Supplementary Figure S1-S6 from ERK Mutations and Amplification Confer Resistance to ERK-Inhibitor Therapy
Authors: Jaiswal Bijay S. , Durinck Steffen , Stawiski Eric W. , Yin Jianping , Wang Weiru , Lin Eva , Moffat John , Martin Scott E. , Modrusan Zora , Seshagiri Somasekar
Published: April 2023

Fig. S1. ERK inhibitors and their effect on MAPK mutant cell lines. A. Structure of ERK inhibitors used in this study. B. Dose response curve of ERK inhibitors on the viability of A375, IPC298, SKMEL30, HCT116, MIA PaCa2 and Panc1 cells. Fig. S2. Western blot analysis of parental, VI-3-R and G994-R HCT116 (A) or MIA PaCa2 (B) cells treated with indicated ERK inhibitors. Fig. S3. Western blot analysis of HCT116 cells (A) and SKMEL30 (B) stably expressing indicated ERK1 or ERK2 mutants. Fig. S4. Copy number and expression analysis of MITF in SKMEL30-ERKi-R cells. A. MITF copy gain in SKMEL30-V11e-R, -VI-3-R and -G994-R. B. MITF copy number vs. expression in SKMEL30-V11e-R, VI-3-R and G994-R cells. Fig. S5. Dose response curve of ERK2 overexpressing IPC298 cells treated with MEK inhibitors GDC-0973 or AZD6244 (A) and ERK2 amplified IPC298-G994-R (B) or MIA PaCa2-S984-R (C) cells treated with indicated ERK-inhibitors from alternate scaffold class. Fig. S6. Dose response curve of parental or ERKi-resistant HCT116 (A) and MIA PaCa2 (B) cells treated with indicated inhibitors. The data shown are same as in Fig. 6B for HCT116 (A) and Fig. 6C for MIA PaCa2 (B) grouped by drug treatment.
Figure S2 from Radiation with STAT3 Blockade Triggers Dendritic Cell–T cell Interactions in the Glioma Microenvironment and Therapeutic Efficacy
Authors: Ott Martina , Kassab Cynthia , Marisetty Anantha , Hashimoto Yuuri , Wei Jun , Zamler Daniel , Leu Jia-Shiun , Tomaszowski Karl-Heinz , Sabbagh Aria , Fang Dexing , Gupta Pravesh , Priebe Waldemar , Zielinski Rafal J. , Burks Jared K. , Long James P. , Kong Ling-Yuan , Fuller Gregory N. , DeGroot John , Sulman Erik P. , Heimberger Amy B.
Published: April 2023

Figure S2 shows survival curves from the radiation dose-finding study in the GL261 model.
Supplementary Figure Legends from Phase 0 Trial of AZD1775 in First-Recurrence Glioblastoma Patients
Authors: Sanai Nader , Li Jing , Boerner Julie , Stark Karri , Wu Jianmei , Kim Seongho , Derogatis Alanna , Mehta Shwetal , Dhruv Harshil D. , Heilbrun Lance K. , Berens Michael E. , LoRusso Patricia M.
Published: April 2023

Supplementary Figure Legends
Supplementary Figures / Table from Loss of E-cadherin Enhances IGF1–IGF1R Pathway Activation and Sensitizes Breast Cancers to Anti-IGF1R/InsR Inhibitors
Authors: Nagle Alison M. , Levine Kevin M. , Tasdemir Nilgun , Scott Julie A. , Burlbaugh Kara , Kehm Justin , Katz Tiffany A. , Boone David N. , Jacobsen Britta M. , Atkinson Jennifer M. , Oesterreich Steffi , Lee Adrian V.
Published: April 2023

Supplementary Figures S1-11 and Table S1
Supplementary Figure Legends from Loss of E-cadherin Enhances IGF1–IGF1R Pathway Activation and Sensitizes Breast Cancers to Anti-IGF1R/InsR Inhibitors
Authors: Nagle Alison M. , Levine Kevin M. , Tasdemir Nilgun , Scott Julie A. , Burlbaugh Kara , Kehm Justin , Katz Tiffany A. , Boone David N. , Jacobsen Britta M. , Atkinson Jennifer M. , Oesterreich Steffi , Lee Adrian V.
Published: April 2023

Supplementary Figure / Table Legends
Figure S4 from Lineage-Specific Alterations in Gynecologic Neoplasms with Choriocarcinomatous Differentiation: Implications for Origin and Therapeutics
Authors: Xing Deyin , Zheng Gang , Pallavajjala Aparna , Schoolmeester J. Kenneth , Liu Yuehua , Haley Lisa , Hu Yan , Liu Li , Logan Lisa , Lin Yuan , Pearce Kathryn E. , Sattler Christopher A. , Tsai Ya Chea , Vang Russell , Hung Chien-Fu , Wu T.-C. , Ronnett Brigitte M.
Published: April 2023

Supplementary Figure S4
Table S6 from The MD Anderson Prostate Cancer Patient-derived Xenograft Series (MDA PCa PDX) Captures the Molecular Landscape of Prostate Cancer and Facilitates Marker-driven Therapy Development
Authors: Palanisamy Nallasivam , Yang Jun , Shepherd Peter D.A. , Li-Ning-Tapia Elsa M. , Labanca Estefania , Manyam Ganiraju C. , Ravoori Murali K. , Kundra Vikas , Araujo John C. , Efstathiou Eleni , Pisters Louis L. , Wan Xinhai , Wang Xuemei , Vazquez Elba S. , Aparicio Ana M. , Carskadon Shannon L. , Tomlins Scott A. , Kunju Lakshmi P. , Chinnaiyan Arul M. , Broom Bradley M. , Logothetis Christopher J. , Troncoso Patricia , Navone Nora M.
Published: April 2023

Ranked expression of genes in MDA PCa 146-10 vs MDA PCa 146-12
Table S1 addendum from The MD Anderson Prostate Cancer Patient-derived Xenograft Series (MDA PCa PDX) Captures the Molecular Landscape of Prostate Cancer and Facilitates Marker-driven Therapy Development
Authors: Palanisamy Nallasivam , Yang Jun , Shepherd Peter D.A. , Li-Ning-Tapia Elsa M. , Labanca Estefania , Manyam Ganiraju C. , Ravoori Murali K. , Kundra Vikas , Araujo John C. , Efstathiou Eleni , Pisters Louis L. , Wan Xinhai , Wang Xuemei , Vazquez Elba S. , Aparicio Ana M. , Carskadon Shannon L. , Tomlins Scott A. , Kunju Lakshmi P. , Chinnaiyan Arul M. , Broom Bradley M. , Logothetis Christopher J. , Troncoso Patricia , Navone Nora M.
Published: April 2023

PDXs growth rate and list of publications in which MDA PCa PDX were used.
Figure S8 from The MD Anderson Prostate Cancer Patient-derived Xenograft Series (MDA PCa PDX) Captures the Molecular Landscape of Prostate Cancer and Facilitates Marker-driven Therapy Development
Authors: Palanisamy Nallasivam , Yang Jun , Shepherd Peter D.A. , Li-Ning-Tapia Elsa M. , Labanca Estefania , Manyam Ganiraju C. , Ravoori Murali K. , Kundra Vikas , Araujo John C. , Efstathiou Eleni , Pisters Louis L. , Wan Xinhai , Wang Xuemei , Vazquez Elba S. , Aparicio Ana M. , Carskadon Shannon L. , Tomlins Scott A. , Kunju Lakshmi P. , Chinnaiyan Arul M. , Broom Bradley M. , Logothetis Christopher J. , Troncoso Patricia , Navone Nora M.
Published: April 2023

Whole-genome copy number analysis of 37 MDA PCa PDXs derived from 28 human donor PCas
Supplementary Methods from Chimeric Antigen Receptor-Glypican-3 T-Cell Therapy for Advanced Hepatocellular Carcinoma: Results of Phase I Trials
Authors: Shi Donghua , Shi Yaoping , Kaseb Ahmed O. , Qi Xingxing , Zhang Yuan , Chi Jiachang , Lu Qing , Gao Huiping , Jiang Hua , Wang Huamao , Yuan Daijing , Ma Hong , Wang Hongyang , Li Zonghai , Zhai Bo
Published: April 2023

Supplementary Methods
Protocol of Study 2 from Chimeric Antigen Receptor-Glypican-3 T-Cell Therapy for Advanced Hepatocellular Carcinoma: Results of Phase I Trials
Authors: Shi Donghua , Shi Yaoping , Kaseb Ahmed O. , Qi Xingxing , Zhang Yuan , Chi Jiachang , Lu Qing , Gao Huiping , Jiang Hua , Wang Huamao , Yuan Daijing , Ma Hong , Wang Hongyang , Li Zonghai , Zhai Bo
Published: April 2023

CG1006-CAR-GPC3 T cells clinical trial
Figure S6 from The MD Anderson Prostate Cancer Patient-derived Xenograft Series (MDA PCa PDX) Captures the Molecular Landscape of Prostate Cancer and Facilitates Marker-driven Therapy Development
Authors: Palanisamy Nallasivam , Yang Jun , Shepherd Peter D.A. , Li-Ning-Tapia Elsa M. , Labanca Estefania , Manyam Ganiraju C. , Ravoori Murali K. , Kundra Vikas , Araujo John C. , Efstathiou Eleni , Pisters Louis L. , Wan Xinhai , Wang Xuemei , Vazquez Elba S. , Aparicio Ana M. , Carskadon Shannon L. , Tomlins Scott A. , Kunju Lakshmi P. , Chinnaiyan Arul M. , Broom Bradley M. , Logothetis Christopher J. , Troncoso Patricia , Navone Nora M.
Published: April 2023

Comparison of copy number changes in MDA PCa 150 PDXs
Supplementary Figure 3 from RNA Splicing Alterations Induce a Cellular Stress Response Associated with Poor Prognosis in Acute Myeloid Leukemia
Authors: Anande Govardhan , Deshpande Nandan P. , Mareschal Sylvain , Batcha Aarif M.N. , Hampton Henry R. , Herold Tobias , Lehmann Soren , Wilkins Marc R. , Wong Jason W.H. , Unnikrishnan Ashwin , Pimanda John E.
Published: April 2023

Supplementary Figure 3, related to main Figure 5.
Supplementary Figure 2 from RNA Splicing Alterations Induce a Cellular Stress Response Associated with Poor Prognosis in Acute Myeloid Leukemia
Authors: Anande Govardhan , Deshpande Nandan P. , Mareschal Sylvain , Batcha Aarif M.N. , Hampton Henry R. , Herold Tobias , Lehmann Soren , Wilkins Marc R. , Wong Jason W.H. , Unnikrishnan Ashwin , Pimanda John E.
Published: April 2023

Supplementary Figure 2, related to main Figure 3
Figure S2 from The MD Anderson Prostate Cancer Patient-derived Xenograft Series (MDA PCa PDX) Captures the Molecular Landscape of Prostate Cancer and Facilitates Marker-driven Therapy Development
Authors: Palanisamy Nallasivam , Yang Jun , Shepherd Peter D.A. , Li-Ning-Tapia Elsa M. , Labanca Estefania , Manyam Ganiraju C. , Ravoori Murali K. , Kundra Vikas , Araujo John C. , Efstathiou Eleni , Pisters Louis L. , Wan Xinhai , Wang Xuemei , Vazquez Elba S. , Aparicio Ana M. , Carskadon Shannon L. , Tomlins Scott A. , Kunju Lakshmi P. , Chinnaiyan Arul M. , Broom Bradley M. , Logothetis Christopher J. , Troncoso Patricia , Navone Nora M.
Published: April 2023

ETV1 rearrangement by RNA in situ hybridization in MDA PCa 177-B
Figure S1 from The MD Anderson Prostate Cancer Patient-derived Xenograft Series (MDA PCa PDX) Captures the Molecular Landscape of Prostate Cancer and Facilitates Marker-driven Therapy Development
Authors: Palanisamy Nallasivam , Yang Jun , Shepherd Peter D.A. , Li-Ning-Tapia Elsa M. , Labanca Estefania , Manyam Ganiraju C. , Ravoori Murali K. , Kundra Vikas , Araujo John C. , Efstathiou Eleni , Pisters Louis L. , Wan Xinhai , Wang Xuemei , Vazquez Elba S. , Aparicio Ana M. , Carskadon Shannon L. , Tomlins Scott A. , Kunju Lakshmi P. , Chinnaiyan Arul M. , Broom Bradley M. , Logothetis Christopher J. , Troncoso Patricia , Navone Nora M.
Published: April 2023

PDXs derived from mixed adeno- and neuroendocrine human prostate carcinoma recapitulating only one morphologic component
Supplementary Table 2 from RABL6A Is an Essential Driver of MPNSTs that Negatively Regulates the RB1 Pathway and Sensitizes Tumor Cells to CDK4/6 Inhibitors
Authors: Kohlmeyer Jordan L. , Kaemmer Courtney A. , Pulliam Casey , Maharjan Chandra K. , Samayoa Allison Moreno , Major Heather J. , Cornick Kendall E. , Knepper-Adrian Vickie , Khanna Rajesh , Sieren Jessica C. , Leidinger Mariah R. , Meyerholz David K. , Zamba K.D. , Weimer Jill M. , Dodd Rebecca D. , Darbro Benjamin W. , Tanas Munir R. , Quelle Dawn E.
Published: April 2023

RNA-Seq Gene Expression
Supplementary Figures 1-3, Supplementary Tables 1-5 from Serum Sex Steroids as Prognostic Biomarkers in Patients Receiving Androgen Deprivation Therapy for Recurrent Prostate Cancer: A Post Hoc Analysis of the PR.7 Trial
Authors: Toren Paul , Hoffman Azik , Ding Keyue , Joncas France-Hélène , Turcotte Véronique , Caron Patrick , Pouliot Frédéric , Fradet Yves , Lévesque Éric , Guillemette Chantal , Klotz Laurence
Published: April 2023

Supplementary Figure 1. Consort diagram of patients included in study; Supplementary Figure 2. Schematic of sex steroids measured using mass spectrometry; Supplementary Figure 3. Prostate cancer survival and overall survival; Supplementary Table 1. Summary results of mass spectrometry based steroid analysis of first samples from PR.7 study; Supplementary Table 2. Pearson intrapatient correlation of measured sex steroids at first measurement during ADT; Supplementary Table 3. Intrapatient correlation of measured steroids in longitudinal samples; Supplementary Table 4. Pearson intrapatient correlation of changes in sex steroids between annual measurements; Supplementary Table 5. Summary of changes over time in measured sex steroids.
Supplementary Table 1 from RABL6A Is an Essential Driver of MPNSTs that Negatively Regulates the RB1 Pathway and Sensitizes Tumor Cells to CDK4/6 Inhibitors
Authors: Kohlmeyer Jordan L. , Kaemmer Courtney A. , Pulliam Casey , Maharjan Chandra K. , Samayoa Allison Moreno , Major Heather J. , Cornick Kendall E. , Knepper-Adrian Vickie , Khanna Rajesh , Sieren Jessica C. , Leidinger Mariah R. , Meyerholz David K. , Zamba K.D. , Weimer Jill M. , Dodd Rebecca D. , Darbro Benjamin W. , Tanas Munir R. , Quelle Dawn E.
Published: April 2023

Antibody Table
Table S3 from Induction of Neoantigen-Specific Cytotoxic T Cells and Construction of T-cell Receptor–Engineered T Cells for Ovarian Cancer
Authors: Matsuda Tatsuo , Leisegang Matthias , Park Jae-Hyun , Ren Lili , Kato Taigo , Ikeda Yuji , Harada Makiko , Kiyotani Kazuma , Lengyel Ernst , Fleming Gini F. , Nakamura Yusuke
Published: April 2023

Sequences of TCRs for generating TCR-engineered T cells.
Supplementary Data Figures from RABL6A Is an Essential Driver of MPNSTs that Negatively Regulates the RB1 Pathway and Sensitizes Tumor Cells to CDK4/6 Inhibitors
Authors: Kohlmeyer Jordan L. , Kaemmer Courtney A. , Pulliam Casey , Maharjan Chandra K. , Samayoa Allison Moreno , Major Heather J. , Cornick Kendall E. , Knepper-Adrian Vickie , Khanna Rajesh , Sieren Jessica C. , Leidinger Mariah R. , Meyerholz David K. , Zamba K.D. , Weimer Jill M. , Dodd Rebecca D. , Darbro Benjamin W. , Tanas Munir R. , Quelle Dawn E.
Published: April 2023

Figures S1 - S8
Supplementary Figures from Smad7 Promotes Healing of Radiotherapy-Induced Oral Mucositis without Compromising Oral Cancer Therapy in a Xenograft Mouse Model
Authors: Luo Jingjing , Bian Li , Blevins Melanie A. , Wang Dongyan , Liang Chao , Du Danfeng , Wu Fanglong , Holwerda Barry , Zhao Rui , Raben David , Zhou Hongmei , Young Christian D. , Wang Xiao-Jing
Published: April 2023

Supplementary Figures
Table S1 from Induction of Neoantigen-Specific Cytotoxic T Cells and Construction of T-cell Receptor–Engineered T Cells for Ovarian Cancer
Authors: Matsuda Tatsuo , Leisegang Matthias , Park Jae-Hyun , Ren Lili , Kato Taigo , Ikeda Yuji , Harada Makiko , Kiyotani Kazuma , Lengyel Ernst , Fleming Gini F. , Nakamura Yusuke
Published: April 2023

List of detected non-synonymous mutations in 7 ovarian cancer patients.
Supplemental Methods from Local Phototherapy Synergizes with Immunoadjuvant for Treatment of Pancreatic Cancer through Induced Immunogenic Tumor Vaccine
Authors: Zhou Feifan , Yang Jingxuan , Zhang Yuqing , Liu Mingyang , Lang Mark L. , Li Min , Chen Wei R.
Published: April 2023

Supplemental Methods
Figure S1 from Induction of Neoantigen-Specific Cytotoxic T Cells and Construction of T-cell Receptor–Engineered T Cells for Ovarian Cancer
Authors: Matsuda Tatsuo , Leisegang Matthias , Park Jae-Hyun , Ren Lili , Kato Taigo , Ikeda Yuji , Harada Makiko , Kiyotani Kazuma , Lengyel Ernst , Fleming Gini F. , Nakamura Yusuke
Published: April 2023

Evaluation of TCR-engineered T cells activation.
Figure S5 from Local Phototherapy Synergizes with Immunoadjuvant for Treatment of Pancreatic Cancer through Induced Immunogenic Tumor Vaccine
Authors: Zhou Feifan , Yang Jingxuan , Zhang Yuqing , Liu Mingyang , Lang Mark L. , Li Min , Chen Wei R.
Published: April 2023

Gross images of treated mice
Supplementary Tables S1-S5 and S7-S9 from Telomerase Reverse Transcriptase Promoter Mutations Identify a Genomically Defined and Highly Aggressive Human Pleural Mesothelioma Subgroup
Authors: Pirker Christine , Bilecz Agnes , Grusch Michael , Mohr Thomas , Heidenreich Barbara , Laszlo Viktoria , Stockhammer Paul , Lötsch-Gojo Daniela , Gojo Johannes , Gabler Lisa , Spiegl-Kreinecker Sabine , Dome Balazs , Steindl Ariane , Klikovits Thomas , Hoda Mir Alireza , Jakopovic Marko , Samarzija Miroslav , Mohorcic Katja , Kern Izidor , Kiesel Barbara , Brcic Luka , Oberndorfer Felicitas , Müllauer Leonhard , Klepetko Walter , Schmidt Wolfgang M. , Kumar Rajiv , Hegedus Balazs , Berger Walter
Published: April 2023

Supplementary Tables S1 to S9 with the exception of Supplementary Table S6
Figure S4 from Local Phototherapy Synergizes with Immunoadjuvant for Treatment of Pancreatic Cancer through Induced Immunogenic Tumor Vaccine
Authors: Zhou Feifan , Yang Jingxuan , Zhang Yuqing , Liu Mingyang , Lang Mark L. , Li Min , Chen Wei R.
Published: April 2023

Interaction between GC and DCs
Supplementary Table S6 from Telomerase Reverse Transcriptase Promoter Mutations Identify a Genomically Defined and Highly Aggressive Human Pleural Mesothelioma Subgroup
Authors: Pirker Christine , Bilecz Agnes , Grusch Michael , Mohr Thomas , Heidenreich Barbara , Laszlo Viktoria , Stockhammer Paul , Lötsch-Gojo Daniela , Gojo Johannes , Gabler Lisa , Spiegl-Kreinecker Sabine , Dome Balazs , Steindl Ariane , Klikovits Thomas , Hoda Mir Alireza , Jakopovic Marko , Samarzija Miroslav , Mohorcic Katja , Kern Izidor , Kiesel Barbara , Brcic Luka , Oberndorfer Felicitas , Müllauer Leonhard , Klepetko Walter , Schmidt Wolfgang M. , Kumar Rajiv , Hegedus Balazs , Berger Walter
Published: April 2023

Supplementary Table S6
Figure S3 from Local Phototherapy Synergizes with Immunoadjuvant for Treatment of Pancreatic Cancer through Induced Immunogenic Tumor Vaccine
Authors: Zhou Feifan , Yang Jingxuan , Zhang Yuqing , Liu Mingyang , Lang Mark L. , Li Min , Chen Wei R.
Published: April 2023

DCs activation
Figure S2 from Local Phototherapy Synergizes with Immunoadjuvant for Treatment of Pancreatic Cancer through Induced Immunogenic Tumor Vaccine
Authors: Zhou Feifan , Yang Jingxuan , Zhang Yuqing , Liu Mingyang , Lang Mark L. , Li Min , Chen Wei R.
Published: April 2023

Effects of GC on tumor cells and immune cells
Supplementary Figure S9 from Telomerase Reverse Transcriptase Promoter Mutations Identify a Genomically Defined and Highly Aggressive Human Pleural Mesothelioma Subgroup
Authors: Pirker Christine , Bilecz Agnes , Grusch Michael , Mohr Thomas , Heidenreich Barbara , Laszlo Viktoria , Stockhammer Paul , Lötsch-Gojo Daniela , Gojo Johannes , Gabler Lisa , Spiegl-Kreinecker Sabine , Dome Balazs , Steindl Ariane , Klikovits Thomas , Hoda Mir Alireza , Jakopovic Marko , Samarzija Miroslav , Mohorcic Katja , Kern Izidor , Kiesel Barbara , Brcic Luka , Oberndorfer Felicitas , Müllauer Leonhard , Klepetko Walter , Schmidt Wolfgang M. , Kumar Rajiv , Hegedus Balazs , Berger Walter
Published: April 2023

Supplementary Figure S9. Immunohistochemical detection of BAP1 expression in the indicated MPM tissue samples.
Figure S1 from Local Phototherapy Synergizes with Immunoadjuvant for Treatment of Pancreatic Cancer through Induced Immunogenic Tumor Vaccine
Authors: Zhou Feifan , Yang Jingxuan , Zhang Yuqing , Liu Mingyang , Lang Mark L. , Li Min , Chen Wei R.
Published: April 2023

Effects of PTT on tumor cells
Supplemental Figure 3 from Multiparametric MR-PET Imaging Predicts Pharmacokinetics and Clinical Response to GDC-0084 in Patients with Recurrent High-Grade Glioma
Authors: Ellingson Benjamin M. , Yao Jingwen , Raymond Catalina , Nathanson David A. , Chakhoyan Ararat , Simpson Jeremy , Garner James S. , Olivero Alan G. , Mueller Lars U. , Rodon Jordi , Gerstner Elizabeth , Cloughesy Timothy F. , Wen Patrick Y.
Published: April 2023

Post-treatment multi-parametric MR-PET imaging measurements and responses for each oral dose of GDC-0084. Post-treatment measurements of A) contrast enhancing tumor volume, B) median 18F-FDG uptake relative to white matter, C) median ADC, D) median FA, E) median Ktrans, F) median vp¬, and G) median rCBV and change in measurements of H) contrast enhancing tumor volume, I) median 18F-FDG uptake relative to white matter, J) median ADC, K) median FA, L) median Ktrans, M) median vp¬, and N) median rCBV for dose levels of 2, 4, 8, 15, 20, 30, 45, and 65mg.
Supplemental Figure 2 from Multiparametric MR-PET Imaging Predicts Pharmacokinetics and Clinical Response to GDC-0084 in Patients with Recurrent High-Grade Glioma
Authors: Ellingson Benjamin M. , Yao Jingwen , Raymond Catalina , Nathanson David A. , Chakhoyan Ararat , Simpson Jeremy , Garner James S. , Olivero Alan G. , Mueller Lars U. , Rodon Jordi , Gerstner Elizabeth , Cloughesy Timothy F. , Wen Patrick Y.
Published: April 2023

Correlation between multi-parametric MR-PET imaging changes before and after GDC-0084. A) Pearson's correlation coefficient (R) and B) resulting p-values describing the association between all imaging measurements. No significant correlations (P<0.05) were observed.
Supplemental Figure 1 from Multiparametric MR-PET Imaging Predicts Pharmacokinetics and Clinical Response to GDC-0084 in Patients with Recurrent High-Grade Glioma
Authors: Ellingson Benjamin M. , Yao Jingwen , Raymond Catalina , Nathanson David A. , Chakhoyan Ararat , Simpson Jeremy , Garner James S. , Olivero Alan G. , Mueller Lars U. , Rodon Jordi , Gerstner Elizabeth , Cloughesy Timothy F. , Wen Patrick Y.
Published: April 2023

Examples of metabolic responders to GDC-0084 as indicated by a decrease in 18F-FDG PET uptake. A-B) Examples of a clear reduction in focal 18F-FDG uptake within the tumor. C-E) Example of more subtle reduction in 18F-FDG uptake after GDC-0084. C and E) demonstrate both focal (tumor) and global (gray matter) reductions in 18F-FDG uptake.
Supplementary Figure S4 from Telomerase Reverse Transcriptase Promoter Mutations Identify a Genomically Defined and Highly Aggressive Human Pleural Mesothelioma Subgroup
Authors: Pirker Christine , Bilecz Agnes , Grusch Michael , Mohr Thomas , Heidenreich Barbara , Laszlo Viktoria , Stockhammer Paul , Lötsch-Gojo Daniela , Gojo Johannes , Gabler Lisa , Spiegl-Kreinecker Sabine , Dome Balazs , Steindl Ariane , Klikovits Thomas , Hoda Mir Alireza , Jakopovic Marko , Samarzija Miroslav , Mohorcic Katja , Kern Izidor , Kiesel Barbara , Brcic Luka , Oberndorfer Felicitas , Müllauer Leonhard , Klepetko Walter , Schmidt Wolfgang M. , Kumar Rajiv , Hegedus Balazs , Berger Walter
Published: April 2023

Supplementary Figure S4: TERT promoter activity and impact of ETS factors in human MPM.
Supplemental Tables S1-S3 from Molecular Profiling of Patients with Pancreatic Cancer: Initial Results from the Know Your Tumor Initiative
Authors: Pishvaian Michael J. , Bender Robert J. , Halverson David , Rahib Lola , Hendifar Andrew E. , Mikhail Sameh , Chung Vincent , Picozzi Vincent J. , Sohal Davendra , Blais Edik M. , Mason Kimberly , Lyons Emily E. , Matrisian Lynn M. , Brody Jonathan R. , Madhavan Subha , Petricoin Emanuel F.
Published: April 2023

Tables detailing testing
Supplemental Material from Targeted Brain Tumor Radiotherapy Using an Auger Emitter
Authors: Pirovano Giacomo , Jannetti Stephen A. , Carter Lukas M. , Sadique Ahmad , Kossatz Susanne , Guru Navjot , Demétrio De Souza França Paula , Maeda Masatomo , Zeglis Brian M. , Lewis Jason S. , Humm John L. , Reiner Thomas
Published: April 2023

Supplemental data
Supplementary Data from FGFR1 Amplification Mediates Endocrine Resistance but Retains TORC Sensitivity in Metastatic Hormone Receptor–Positive (HR+) Breast Cancer
Authors: Drago Joshua Z. , Formisano Luigi , Juric Dejan , Niemierko Andrzej , Servetto Alberto , Wander Seth A. , Spring Laura M. , Vidula Neelima , Younger Jerry , Peppercorn Jeffrey , Yuen Megan , Malvarosa Giuliana , Sgroi Dennis , Isakoff Steven J. , Moy Beverly , Ellisen Leif W. , Iafrate A. John , Arteaga Carlos L. , Bardia Aditya
Published: April 2023

Supplementary figures
Supplimentary_Figure1-14 and Table 1-2 from Combined CDK4/6 and Pan-mTOR Inhibition Is Synergistic Against Intrahepatic Cholangiocarcinoma
Authors: Song Xinhua , Liu Xianqiong , Wang Haichuan , Wang Jingxiao , Qiao Yu , Cigliano Antonio , Utpatel Kirsten , Ribback Silvia , Pilo Maria G. , Serra Marina , Gordan John D. , Che Li , Zhang Shanshan , Cossu Antonio , Porcu Alberto , Pascale Rosa M. , Dombrowski Frank , Hu Hongbo , Calvisi Diego F. , Evert Matthias , Chen Xin
Published: April 2023

Supplementary Figure 1. Activation of the CDK4/6 axis in human intrahepatic cholangiocarcinoma (ICC) specimens. Supplementary Figure 2. Levels of Rb1, CDK4, CDK6, E2F1, and Cyclin E1 mRNA in human intrahepatic cholangiocarcinoma (ICC) from The Cancer Genome Atlas (TCGA) and National Cancer Institute (NCI) datasets. Supplementary Figure 3: Effect of Palbociclib on ICC cell growth. Supplementary Figure 4: Effect of Palbociclib on the levels of putative target proteins in human ICC cell lines. Supplementary Figure 5. Inhibition of CyclinD1 (CCND1) expression enhances tumor cell growth suppressor capacity of Palbobiclib. Supplementary Figure 6. Correlation analysis of Retinoblastoma (Rb) expression and the growth inhibitory effects of Palbociclib. Supplementary Figure 7. Palbociclib inhibits proliferation of ICC cell lines in colony formation assays. Supplementary Figure 8. Retinoblastoma-dependent cell growth inhibition effect of long-term Palbociclib treatment in ICC cells. Supplementary Figure 9. Effect of combined Palbociclib/MLN0128 treatment on cell proliferation. Supplementary Figure 10. Synergistic effect of Palbociclib/MLN0128 combination in ICC cell lines. Supplementary Figure 11. Effect of combined Palbociclib/MLN0128 administration on cell cycle of ICC cell lines. Supplementary Figure 12. Effect of Palbociclib/MLN0128 on putative target proteins in intrahepatic cholangiocarcinoma (ICC) cell lines. Supplementary Figure 13. Overview of the apoptosis rate in ICC lesions from AKT/YapS127A mice subjected to the various treatment regimens. Supplementary Figure 14. Effect of Palbociclib/MLN0128 treatment on putative target proteins in AKT/YapS127A mice. Supplementary Table 1: Clinicopathological features of intrahepatic cholangiocarcinoma (ICC) patients Supplementary Table 2: Western blotting antibody information
Figure S7 from KRAS G12C NSCLC Models Are Sensitive to Direct Targeting of KRAS in Combination with PI3K Inhibition
Authors: Misale Sandra , Fatherree Jackson P. , Cortez Eliane , Li Chendi , Bilton Samantha , Timonina Daria , Myers David T. , Lee Dana , Gomez-Caraballo Maria , Greenberg Max , Nangia Varuna , Greninger Patricia , Egan Regina K. , McClanaghan Joseph , Stein Giovanna T. , Murchie Ellen , Zarrinkar Patrick P. , Janes Matthew R. , Li Lian-Sheng , Liu Yi , Hata Aaron N. , Benes Cyril H.
Published: April 2023

Supplementary Figure 7
Table S2 from Adenocarcinoma of the Uterine Cervix Shows Impaired Recruitment of cDC1 and CD8+ T Cells and Elevated β-Catenin Activation Compared with Squamous Cell Carcinoma
Authors: Rotman Jossie , Heeren A. Marijne , Gassama Awa A. , Lougheed Sinead M. , Pocorni Noëlle , Stam Anita G.M. , Bleeker Maaike C.G. , Zijlmans Henry J.M.A.A , Mom Constantijne H. , Kenter Gemma G. , Jordanova Ekaterina S. , de Gruijl Tanja D.
Published: April 2023

Clinical characteristics of the SCC study population
Figure S4 from KRAS G12C NSCLC Models Are Sensitive to Direct Targeting of KRAS in Combination with PI3K Inhibition
Authors: Misale Sandra , Fatherree Jackson P. , Cortez Eliane , Li Chendi , Bilton Samantha , Timonina Daria , Myers David T. , Lee Dana , Gomez-Caraballo Maria , Greenberg Max , Nangia Varuna , Greninger Patricia , Egan Regina K. , McClanaghan Joseph , Stein Giovanna T. , Murchie Ellen , Zarrinkar Patrick P. , Janes Matthew R. , Li Lian-Sheng , Liu Yi , Hata Aaron N. , Benes Cyril H.
Published: April 2023

Supplementary Figure 4
Figure S3 from Adenocarcinoma of the Uterine Cervix Shows Impaired Recruitment of cDC1 and CD8+ T Cells and Elevated β-Catenin Activation Compared with Squamous Cell Carcinoma
Authors: Rotman Jossie , Heeren A. Marijne , Gassama Awa A. , Lougheed Sinead M. , Pocorni Noëlle , Stam Anita G.M. , Bleeker Maaike C.G. , Zijlmans Henry J.M.A.A , Mom Constantijne H. , Kenter Gemma G. , Jordanova Ekaterina S. , de Gruijl Tanja D.
Published: April 2023

TCGA derived mRNAseq gene signatures and their correlation with recurrence free survival
Figure S3 from KRAS G12C NSCLC Models Are Sensitive to Direct Targeting of KRAS in Combination with PI3K Inhibition
Authors: Misale Sandra , Fatherree Jackson P. , Cortez Eliane , Li Chendi , Bilton Samantha , Timonina Daria , Myers David T. , Lee Dana , Gomez-Caraballo Maria , Greenberg Max , Nangia Varuna , Greninger Patricia , Egan Regina K. , McClanaghan Joseph , Stein Giovanna T. , Murchie Ellen , Zarrinkar Patrick P. , Janes Matthew R. , Li Lian-Sheng , Liu Yi , Hata Aaron N. , Benes Cyril H.
Published: April 2023

Supplementary Figure 3
Figure S1 from Adenocarcinoma of the Uterine Cervix Shows Impaired Recruitment of cDC1 and CD8+ T Cells and Elevated β-Catenin Activation Compared with Squamous Cell Carcinoma
Authors: Rotman Jossie , Heeren A. Marijne , Gassama Awa A. , Lougheed Sinead M. , Pocorni Noëlle , Stam Anita G.M. , Bleeker Maaike C.G. , Zijlmans Henry J.M.A.A , Mom Constantijne H. , Kenter Gemma G. , Jordanova Ekaterina S. , de Gruijl Tanja D.
Published: April 2023

Gating strategies of migratory cDC, APC, cDC1 and pDC
Data S3 from KRAS G12C NSCLC Models Are Sensitive to Direct Targeting of KRAS in Combination with PI3K Inhibition
Authors: Misale Sandra , Fatherree Jackson P. , Cortez Eliane , Li Chendi , Bilton Samantha , Timonina Daria , Myers David T. , Lee Dana , Gomez-Caraballo Maria , Greenberg Max , Nangia Varuna , Greninger Patricia , Egan Regina K. , McClanaghan Joseph , Stein Giovanna T. , Murchie Ellen , Zarrinkar Patrick P. , Janes Matthew R. , Li Lian-Sheng , Liu Yi , Hata Aaron N. , Benes Cyril H.
Published: April 2023

Supplementary Data 3
Data S2 from KRAS G12C NSCLC Models Are Sensitive to Direct Targeting of KRAS in Combination with PI3K Inhibition
Authors: Misale Sandra , Fatherree Jackson P. , Cortez Eliane , Li Chendi , Bilton Samantha , Timonina Daria , Myers David T. , Lee Dana , Gomez-Caraballo Maria , Greenberg Max , Nangia Varuna , Greninger Patricia , Egan Regina K. , McClanaghan Joseph , Stein Giovanna T. , Murchie Ellen , Zarrinkar Patrick P. , Janes Matthew R. , Li Lian-Sheng , Liu Yi , Hata Aaron N. , Benes Cyril H.
Published: April 2023

Supplementary Data 2
Supplementary Figures S1 - S10 from Tyrosine Kinase Inhibitors Increase MCL1 Degradation and in Combination with BCLXL/BCL2 Inhibitors Drive Prostate Cancer Apoptosis
Authors: Arai Seiji , Jonas Oliver , Whitman Matthew A. , Corey Eva , Balk Steven P. , Chen Sen
Published: April 2023

Fig. S1. Doxycycline-induced depletion of MCL1; Fig. S2. MCL1, BCLXL, and BCL2 expression in PCa databases, and comparison of the protein levels among benign prostate cell, PCa cells, and patient-derived xenograft (PDX) cells; Fig. S3. BH3 mimetics diminished the tumor growth of prostate cancer xenograft with MCL1 depletion; Fig. S4. Effects of lapatinib and ABT-737 in LNCaP and additional cell lines; Fig. S5. Effects of various kinase inhibitors on MCL1; Fig. S6. Effects of EGFR/ERBB2 inhibition on MCL1 mRNA and proteasome-dependent degradation of MCL1; Fig. S7. EGFR inhibition enhances MCL1 degradation by GSK3β-independent mechanism; Fig. S8. Erlotinib mediated MCL1 degradation is not through GSK3β or previously characterized ubiquitin ligases or DUBs; Fig. S9. Cabozantinib and sorafenib mediate MCL1 degradation that is independent of GSK3β; Fig. S10. Apoptosis mediated by single and combination therapies delivered locally into xenografts by implantable microdevice.
Supplementary Data from Genomic and Clinicopathologic Characterization of ATM-deficient Prostate Cancer
Authors: Kaur Harsimar , Salles Daniela C. , Murali Sanjana , Hicks Jessica L. , Nguyen Minh , Pritchard Colin C. , De Marzo Angelo M. , Lanchbury Jerry S. , Trock Bruce J. , Isaacs William B. , Timms Kirsten M. , Antonarakis Emmanuel S. , Lotan Tamara L.
Published: April 2023

Supplementary Figure S1: Metastasis-free survival of surgically-treated patients stratified by ATM status on immunohistochemistry Supplementary Figure S2: ATM immunostaining of primary and metastatic tumor from case ATM44.
Supplementary Data from Genomic and Clinicopathologic Characterization of ATM-deficient Prostate Cancer
Authors: Kaur Harsimar , Salles Daniela C. , Murali Sanjana , Hicks Jessica L. , Nguyen Minh , Pritchard Colin C. , De Marzo Angelo M. , Lanchbury Jerry S. , Trock Bruce J. , Isaacs William B. , Timms Kirsten M. , Antonarakis Emmanuel S. , Lotan Tamara L.
Published: April 2023

Supplementary Table S1
Supp Figure S4 from Serum Alpha-fetoprotein Levels and Clinical Outcomes in the Phase III CELESTIAL Study of Cabozantinib versus Placebo in Patients with Advanced Hepatocellular Carcinoma
Authors: Kelley Robin Kate , Meyer Tim , Rimassa Lorenza , Merle Philippe , Park Joong-Won , Yau Thomas , Chan Stephen L. , Blanc Jean-Frederic , Tam Vincent C. , Tran Albert , Dadduzio Vincenzo , Markby David W. , Kaldate Rajesh , Cheng Ann-Lii , El-Khoueiry Anthony B. , Abou-Alfa Ghassan K.
Published: April 2023

Figure S4. Percent change in target lesion sum of diameters from baseline at Week 8 versus percent change in AFP from baseline at Week 8 in the cabozantinib group (N=228 evaluable patients) and the placebo group (N=109 evaluable patients).
Supp Figure S3 from Serum Alpha-fetoprotein Levels and Clinical Outcomes in the Phase III CELESTIAL Study of Cabozantinib versus Placebo in Patients with Advanced Hepatocellular Carcinoma
Authors: Kelley Robin Kate , Meyer Tim , Rimassa Lorenza , Merle Philippe , Park Joong-Won , Yau Thomas , Chan Stephen L. , Blanc Jean-Frederic , Tam Vincent C. , Tran Albert , Dadduzio Vincenzo , Markby David W. , Kaldate Rajesh , Cheng Ann-Lii , El-Khoueiry Anthony B. , Abou-Alfa Ghassan K.
Published: April 2023

Figure S3. AFP response cutoff determination for overall survival by maximally selected rank statistics. Cutpoint determination plots showing (A) histogram distribution and (B) rank statistic plot of percent AFP change from baseline at Week 8 for patients in the cabozantinib group with baseline AFP {greater than or equal to}20 ng/mL. *Calculated value of 0.48%, rounded to 0% for all subsequent analyses.
Supplementary Data from MRI Tumor Regression Grade and Circulating Tumor DNA as Complementary Tools to Assess Response and Guide Therapy Adaptation in Rectal Cancer
Authors: Khakoo Shelize , Carter Paul David , Brown Gina , Valeri Nicola , Picchia Simona , Bali Maria Antonietta , Shaikh Ridwan , Jones Thomas , Begum Ruwaida , Rana Isma , Wotherspoon Andrew , Terlizzo Monica , von Loga Katharina , Kalaitzaki Eleftheria , Saffery Claire , Watkins David , Tait Diana , Chau Ian , Starling Naureen , Hubank Michael , Cunningham David
Published: April 2023

Supplementary methods, tables S1-S3 and figures S1-S4
Supplemental Figures from Integrative Molecular Characterization of Resistance to Neoadjuvant Chemoradiation in Rectal Cancer
Authors: Kamran Sophia C. , Lennerz Jochen K. , Margolis Claire A. , Liu David , Reardon Brendan , Wankowicz Stephanie A. , Van Seventer Emily E. , Tracy Adam , Wo Jennifer Y. , Carter Scott L. , Willers Henning , Corcoran Ryan B. , Hong Theodore S. , Van Allen Eliezer M.
Published: April 2023

Supplemental Figures 1-12
Suppl FigS6 from The Proteome of Prostate Cancer Bone Metastasis Reveals Heterogeneity with Prognostic Implications
Authors: Iglesias-Gato Diego , Thysell Elin , Tyanova Stefka , Crnalic Sead , Santos Alberto , Lima Thiago S. , Geiger Tamar , Cox Jürgen , Widmark Anders , Bergh Anders , Mann Matthias , Flores-Morales Amilcar , Wikström Pernilla
Published: April 2023

Suppl FigS6
Figure S2 from Randomized Phase 0/I Trial of the Mitochondrial Inhibitor ME-344 or Placebo Added to Bevacizumab in Early HER2-Negative Breast Cancer
Authors: Quintela-Fandino Miguel , Morales Serafín , Cortés-Salgado Alfonso , Manso Luis , Apala Juan V. , Muñoz Manuel , Gasol Cudos Ariadna , Salla Fortuny Joel , Gion María , Lopez-Alonso Antonio , Cortés Javier , Guerra Juan , Malón Diego , Caleiras Eduardo , Mulero Francisca , Mouron Silvana
Published: April 2023

Supplementary Figure 2: Pharmacodynamic endpoints: intra-tumor VEGF levels and microvessel density.
Suppl FigS5 from The Proteome of Prostate Cancer Bone Metastasis Reveals Heterogeneity with Prognostic Implications
Authors: Iglesias-Gato Diego , Thysell Elin , Tyanova Stefka , Crnalic Sead , Santos Alberto , Lima Thiago S. , Geiger Tamar , Cox Jürgen , Widmark Anders , Bergh Anders , Mann Matthias , Flores-Morales Amilcar , Wikström Pernilla
Published: April 2023

Suppl FigS5