bluuebunny/crossref_metadata_2025 huggingface dataset:
ЛІТЕРАТУРНІ ПОДКАСТИ В МЕДІАПРОСТОРІ: ТЕМАТИЧНО-ЖАНРОВІ ПРІОРИТЕТИ
Authors: Kovtun N.
Published: May 2023

The purpose of the study is to trace the specifics of podcasts on literary topics, clarify the peculiarities of their functioning in Ukrainian media resources, and determine their themes and the most common genre forms of representation.

Research methodology. To study the chosen topic and solve the set tasks, such research methods as analysis, synthesis, generalization, monitoring, and observation were chosen. The method of qualitative content analysis and statistical methods were also adopted. In particular, through monitoring and observation methods, an extensive array of podcasts dedicated to literature was identified, and the descriptive way allowed for the representation of their specificity. The method of qualitative content analysis was applied to identify the topics of literary podcasts, where the categories and units of study were the verbal elements of the content; with the help of statistical observation and grouping methods, we managed to summarize information about the genre priorities of podcasts about literature.

Results. The specificity of literary podcasts functioning has been identified, and the main mobile applications and media resources on which literature-related podcasts can be listened to have been determined (various podcasting platforms, websites for promoting reading and selling paper and audio books, YouTube channels and library websites, online radio stations, and other media). The most well-known literary podcasts in the Ukrainian segment of the internet during their existence have been characterized, their content has been described, and the most popular genre forms of presentation have been determined.

Scientific novelty. For the first time, information on Ukrainian literary podcasts has been summarized, the media resources where they can be listened to have been identified, and their topics and their genre forms of presentation have been determined.

Practical meaning. The scientific article will be relevant primarily for specialists involved in the preparation and dissemination of literature podcasts: journalists and radio presenters, writers, literary critics, librarians, and all those who are interested in literature. In addition, the materials are valuable for the practical activities of future media workers. The attention to literary podcasts contributes to popularizing writers, their works, and literature in general.

Key words: podcast, podcasting, podcast platform, literary podcast, podcast genre.
BATI SİNEMASINDA TÜRK İMAJI YANSIMASI: "11 EYLÜL 1683 (11 SETTEMBRE 1683)" FİLMİ ÖRNEĞİ
Authors: ÖZTAŞ Sezai , HACIOĞLU Uğur
Published: May 2023

Köprülüler Dönemi itibarıyla yakaladığı düzen ve istikrarın devamında tekrardan eski kudretine dönme arzusu taşıyan Osmanlı Devleti’nde bu hedef için en önemli harekâtlardan biri, Temmuz 1683-Eylül 1683 tarihleri arasında gerçekleşen ve XVII. yüzyılın en önemli kuşatma savaşlarından biri olan II. Viyana Kuşatması’dır. Kuşatma, gerçekleştiği şartlar ve sonrasında meydana gelen diplomatik ve siyasal sonuçlarıyla Osmanlı Devleti’nin Avrupa ile ilişkileri açısından önemli kırılma anlarından biridir. Savaş sonrası süreçte devletin daha önce karşılaşmadığı derecede büyük toprak kayıpları yaşamaya başlaması teknolojik, ekonomik, siyasal ve askerî açıdan gittikçe Avrupa’nın gerisinde kalınan bir dönemin başlangıcı olmuştur. 2012 yılında Polonya ile İtalya’nın ortak yapımı olan ve Renzo Martinelli’nin yönetmenliğinde izleyiciyle buluşan “11 Eylül 1683 (11 Settembre 1683)” filmi II. Viyana Kuşatması’nın sebepleri ve savaşı aktarması bakımından önemli bir filmdir. Filmde savaşın seyrini etkileyen olayların aktarılmasının yanında kahraman özelinde Marco d'Aviano, Merzifonlu Kara Mustafa Paşa ve III. Jan Sobieski gibi tarihsel şahsiyetlerin üzerinde durulmuştur. Aynı zamanda tarihsel ve kültürel bakımdan bir Türk imajı çizilmiştir. Çalışmada, Osmanlı Devleti’nin gerçekleştirmiş olduğu II. Viyana Kuşatması, kavramsal olarak imaj, Türk imajı ve sinemaya yansımaları ile “11 Eylül 1683” filmi özelinde Batı sinemasındaki Türk imajının yansımaları incelenmiştir.
An Investigation into Conceptual Metaphors of WATER in English and Vietnamese Poetry
Authors: Chi Le Thi Giao , Luu Trang
Published: May 2023

This study is conducted with the aim of identifying conceptual metaphors of WATER in English and Vietnamese poetry. It seeks to find out the similarities and differences in the conceptualization of metaphors of WATER in the two languages; then suggest some implications for the teaching and learning process. In the study, descriptive, quantitative, qualitative approaches and a contrastive analysis are employed. 150 English and 150 Vietnamese samples are taken from a corpus of English and Vietnamese poems from the 19th and 20th centuries. The results show that ten conceptual metaphors of WATER in both English and Vietnamese are discovered within the scope of the study. Both English and Vietnamese poets make use of three types of poetic reworking of conventional metaphors, namely extending, elaboration, and combining. Since the meaning of a metaphor is influenced by culture and personal experiences, the concepts in the metaphors might differ significantly across Vietnamese and English cultures.
Perception, Attitude and Practice of English Presentation Skills by Students at the University of Danang-University of Foreign Language Studies, Vietnam
Authors: Luu Quy Khuong , Luu Ngoc Bao Thi
Published: May 2023

The study aims to find out the perception, attitude, and practice of English presentation skills of first-year English students from the Faculty of Foreign Language Teacher Education and the Faculty of English at The University of Danang-University of Foreign Language Studies (hereafter called EFL students for brief) as well as to propose appropriate solutions to assist them. Data were collected from 200 questionnaires, and the analysis of the in-depth interviews was conducted with 10 student informants and observations of 30 students in total. The findings showed that most students were familiar with English presentation skills. Also, they were aware of the importance of presentation skills and agreed on the necessity for a successful presentation. Knowledge was what caused participants the most difficulties during the preparation stage, and when presenting, students struggled the most not to replicate the textbook word-by-word. To solve these problems, several solutions were discussed in the study.
The Validity Measurement of Murder using Model Penal Code of Statutory Codes and Common Law Jurisdiction based on Heidegger’s Theory of Truth
Authors: LLARENA ZHARAMA
Published: May 2023

Heidegger’s philosophy of truth is a critical revelation concerning criminalization. The idea of truth has been a long series of debates among scholastic artworks since the idea of man’s interactions cannot be extrapolated to knowledge-seeking existence. Hence, evidence law pertaining to types of killings, such as degrees of murder, with depraved heart killings of another, based on statutory codes and murder from common law jurisdiction, have elements for evaluation of its severity of criminal offense subject to punishment based on Model Penal Code. Although centuries have passed, erudite articulation of these issues led to the development of questions, like ‘what are the elements of murder crucial for unlawful perpetration?’, ‘what are the arguments concerning exact copy of legal instruments?’ or ‘what must be the facts needed to make it essential for the validity of measurement concerning crime perpetration of murder?’ for tools of becoming. This article asserts that when the concept of truth, known as Aletheia (disclosure), is applied to criminal law, there must be three repercussions for this truth characterization. First, Aletheia is not restricted to propositions resulting in the discovery of its various forms depicting Being-in-the-World. Second, the idea of truth does not only involve a substance for language and thought but also exposure to factual materials. Lastly, Aletheia simultaneously reveals and hides planned occasions, constantly discussing that the truth is always a becoming process, a series of returning existence. Every discussion of truth in murder under criminal law has the tendency to create another intricate philosophical issue. The three exceptional principles of truth, namely, correspondence, coherence, and pragmatic theories, are deemed to be inadequate in resolving the questions on proof of facts, as mentioned, due to the issue of existence. The theory of Heidegger suggests that we must rely on the ancient Greek concept of ‘unconcealment.’ Upon this validation, this paper applies critical assessment to reveal the concept of truth, seeking justice based on proof of facts involving the crime perpetration of murder constituting Heidegger’s opinions and judicial decisions. Heidegger’s truth is designed to Dasein (existence) as for being. The philosopher believes in the existence of truth due to exposure to its existence; hence, the Australian Legal System serves as the common ground in formulating laws based on legal theories as a legislative framework pre-emptive to constitutional law towards application of its legal practice and regulatory policies to be in harmony set for amendments of constitutional gaps in terms of applying the critical assessment of Heidegger to other comparative laws based on political agendas for monetary success.
Identification of Dam Construction Risks to Job Owners (Dam Construction in East Java)
Authors: Pratama Firman Yudi , Zacoeb Achfas , Wijaya Ming Narto
Published: May 2023

Approach to risk management, knowing the potential risks in realizing the construction of dam construction on the side of the work owner in the East Java area. In constructing a dam, construction on the job owner can affect the project's success. A practical risk management approach is carried out to achieve schedule, cost, quality, and service. This research aims to identify risks and provide a priority order of risks for the owner of the dam construction project in East Java that are most likely to occur to minimize the consequences arising from these risks. The identified risks will then be researched using the Failure Mode and Effect Analysis (FMEA) method. Then, the highest risk priority sequence will be obtained to determine the appropriate risk response in addressing these potential risks. In the next dam construction, the work owner will know the most significant potential risks to minimize cost overruns, time, and quality.
Konsep Distribusi dan Base Value Sistem Ekonomi Islam
Authors: Samsuduha St
Published: May 2023

This paper reviews the concept of distribution and the base value of the Islamic economic system. These two themes are interrelated discourses with one another. As understood, the Islamic economic system aspires to an economic order that is just and beneficial for human life. Therefore, distribution as one of the market instruments in the economic world must effectively take place in the corridor of positive and fair values. The results of the study in this paper concluded that; First, distribution in economic studies is a system of distributing goods and services from producers to consumers. This process is a stage that takes place to synchronize the stages of production of goods with sales. Distribution is an important aspect that determines the adequacy of goods needs in the community. Therefore, the balance can be maximized through the selection of distribution channels in an effective, fair and sustainable manner. Second, the Islamic economic system provides a basic value formulation that can be used as a benchmark in the distribution process. Thus, the distribution made must be in line with the basic value of ownership; the basic value of freedom; basic values of justice; basic value of balance; and the value of togetherness
Pernikahan Semarga Bagi Masyarakat Lamaholot dalam Perspektif Hukum Islam
Authors: Ratuloly Hidayatullah , Akil Muhammad , Syarifuddin Said
Published: May 2023

In the customary law of Lamaholot concerning the prohibition of marriages that are patrilineal in nature or draw a lineage from the father, it is called "Kakan Noon Aring" (brother and sister). The purpose of this research is to find out the views of the Lamaholot community regarding family marriages in Lamahala Jaya Village and how the sanctions are given if they have violated the legal provisions in Lamahala Jaya Village in an Islamic view. The results of this study indicate that the majority of the Lamaholot community still strongly adheres to the customary law governing marriage, which can only be carried out if the couple is of a different ethnicity, clan or clan. In Islamic law, it is forbidden to marry a mother, daughter, sister, mother, father or mother, grandchildren, nieces, breast-feeding women and siblings, parents-in-law, step-daughter, son-in-law and marrying two women who are sisters at the same time so that it is clear that there is no prohibition on clan marriage in Islamic law is (mubah).
Praktik Bagi Hasil Ternak Sapi (Teseng) Ditinjau Dari Hukum Islam
Authors: Sari Salsa Miranda , Hasibuddin M , Zaenal Abdul Qahar
Published: May 2023

Penelitian ini bertujuan untuk mengetahui praktik bagi hasil ternak sapi (teseng) di desa Pacubbe Kecematan Cenrana Kabupaten Bone dan pandangan hukum islam tentang praktik bagi hasil ternak sapi (teseng). Penelitian ini bertujuan untuk mengetahui praktik bagi hasil ternak sapi (teseng) di desa Pacubbe Kecematan Cenrana Kabupaten Bone dan pandangan hukum islam tentang praktik bagi hasil ternak sapi (teseng). Penelitian ini merupakan penelitian kualitatif. Teknik pengumpulan data menggunakan observasi dengan cara mengamati langsung di Desa Pacubbe, selanjutnya dengan cara wawancara sebagai pendukung guna melengkapi informasi penelitian, serta dengan dokumentasi dan studi kepustakaan guna melengkapi data dan teori. Sumber data yang penulis gunakan adalah terdiri dari sumber data primer yaitu data yang diperoleh dari hasil wawancara dan observasi dari kedua belah pihak yaitu pemilik sapi dan pengelola sapi dan sumber data sekunder yaitu data yang diperoleh melalui penelaan buku-buku yang berkaitan dan menunjang penelitian ini. Setelah data terkumpul penulis melakukan analisa data dengan menggunakan metode kualitatif deskriptif. Dari penelitian yang dilakukan penulis dapat simpulkan bahwa pada pelaksanaan sistem bagi hasil di Desa Pacubbe Kecamatan Cenrana Kabupaten Bone akad yang terjalin antara shahibul maal dengan mudharib adalah akad lisan dengan keuntungan nisbah bagi hasil dibagi dua atau satu banding satu. Menurut tinjauan ekonomi Islam tentang pelaksanaan sistem bagi hasil ternak sapi (teseng) di Desa Pacubbe Kecamatan Cenrana Kabupaten Bone dalam pelaksanaannya sudah sesuai dengan prinsip syariah tapi perlu disempurnakan seperti adanya perjanjian tertulis agar tidak terjadi kesalapahaman dan konflik, sehingga bisa menimbulkan perselisihan yang dapat mengganggu terpenuhinya hak dan kewajiban pemodal dan pengelola dalam menjalankan kerjasama. Kata Kunci : Bagi Hasil, Ternak Sapi (Teseng), Hukum Islam
The Degree Of Whistleblowing Intention And Its Determinants Among Halal Food Manufacturing Employees
Authors: Yusoff Nabiilah , Ahmad Anis Najiha , Md Dahlal Norazilawati
Published: May 2023

Any fraud or wrongdoing that occurs in the halal food industry can have a severe impact on the safety and integrity of halal food products. Whistleblowing is one of the methods that can be used to combat fraudulent halal food and food safety issues. Some illegal, unsafe, or unethical behaviour may not be discovered by top management or Halal authorities. The safety and integrity of Halal food industry depend on the honesty of the food producers. Hence, whistleblowing is encouraged and should be practiced to counter the possibility of Halal food fraud occurrence. The purpose of this research is to determine the level of whistleblowing intention among employees of Halal certified food manufacturing companies and assess the level of factors influencing this intention (attitude, subjective norm, perceived behavioural control, perceived organizational support, religious obligation, knowledge, personal cost reporting, personal responsibility, and seriousness of wrongdoing). The survey was collected among 210 of employees of Halal certified food manufacturing companies in Selangor via a structured questionnaire. The results revealed that the level of whistleblowing intention among employees is very good and most means scores of the factors influencing employee’s decision to whistleblow are positive and favourable. The low mean score for personal cost reporting suggests minimal perceived personal costs associated with whistleblowing. Recommendations to implement whistleblowing system as food fraud prevention needs to be explored as employees’ intention was positive. Suggestions are also presented to ensure that reporting any wrongdoing within companies has a positive effect in preventing such incident.
Synthesis and In Vitro Anticancer Evaluation of Chrysin Containing Hybrids and Other Chrysin Derivatives
Authors: Mayer Szabolcs , Herr Dominika Mária , Nagy Nóra , Donkó-Tóth Viktória , Keglevich Péter , Weber Márton , Dékány Miklós , Hazai László
Published: May 2023

Chrysin, a well-known naturally occurring flavonoid having several biological effects including antiproliferative activity, was coupled with different pharmacophore structures. Coupling was carried out with spacers of different lengths and types. Structures selected for hybrid formation were amines, cyclic amino acid esters, and (hetero)aromatic compounds. In addition, vindoline, which is a Vinca alkaloid containing an indole skeleton, was also used. The alkylation of amines in the presence of carbonate base resulted in an interesting carbamate side product formation beside the expected amine. We also present the detailed structure elucidation of the carbamates. The in vitro anticancer activities of the synthesized derivatives were examined against 60 human tumor cell lines in National Cancer Institute (NCI, USA).
Exploring the Use of Particle and Kalman Filters for Obstacle Detection in Mobile Robots
Authors: Gyenes Zoltán , Bölöni Ladislau , Gincsainé Szádeczky-Kardoss Emese
Published: May 2023

The present study aims to explore the adaptation of estimation methodologies, specifically Particle filters and Kalman filters, for the purpose of determining the position and velocity vector of obstacles within the operational workspace of mobile robots. These algorithms are commonly employed in the motion planning tasks of mobile robots for the estimation of their own position. The proposed methodology utilizes LiDAR sensor data to estimate the position vectors and calculate the velocity vectors of obstacles. Additionally, an uncertainty parameter can be determined using the introduced perception method. The performance of the newly adapted algorithms is evaluated through comparison of the absolute error in position and velocity vector estimations.
Effects Of Some Fungal Secondary Metabolite Against Some Cancer Cell Line
Authors: Noman Saja Jamal , Ahmad Hanan Shihab
Published: May 2023

The promising feature of the fungi from the marine environment as a source for anticancer agents belongs to the fungal ability to produce several compounds and enzymes which contribute effectively against the cancer cells growth. Moreover, the compounds produced during the secondary metabolic process acts by changing the cell morphology and DNA fragmentation leading to apoptosis of the cancer cells. When compared to the other chemicals in the investigation, gliotoxin demonstrated the most cytotoxic effect. These findings suggest that gliotoxin could be a potential virulence factor of Aspergillus fumigatus during infection. Anti Cancer, the dreadful disease that spreads throughout the body, bringing its cells closer to death than life expectancy, will be defeated or at least slowed by natural plants. Many researchers and clinicians are familiar with the treatment of numerous plants, such as Rheum ribes. Cancer studies have shown that the usage of some medicinal herbs can help to minimize the severity of this dreadful disease, and plant care is also well understood.
Bangladesh Journal of Medical Science Vol.22 (Special Issue) 2023 p.133-137
SISTEM PENGGAJIAN PROFIT SHARING BERASASKAN PANCASILA DAN KEBERLANGSUNGAN USAHA
Authors:   Universitas Trunojoyo Madura Indonesia, Rimawati Yuni , Bullah Habi ,   Universitas Trunojoyo Madura Indonesia, Kompyurini Nurul ,   Universitas Trunojoyo Madura Indonesia
Published: May 2023

Research Purposes. This article aims to provide ideas on how to implement a profit-sharing payroll system based on Pancasila philosophy. Research Methods. Based on the assumptions we built, the profit-sharing payroll system based on Pancasila, not only increases productivity and profitability, but also employee loyalty. Research Results and Findings. With a profit-sharing payroll system based on the Pancasila philosophy, the relationship between workers and employers is based on good values, such as being honest, fair, helping each other. These values of kindness make working relationships not solely for personal gain but also considering the interests of others as a form of carrying out the commands of God Almighty.
FAKTOR DETERMINAN KEJADIAN DIABETES MELITUS
Authors: Tiawati Holis , Febrianti Thresya
Published: May 2023

Background: Diabetes mellitus is a non-communicable disease that increases every year and causes many losses for sufferers and the health financing sector due to complications such as heart and blood vessel problems, stroke, kidney failure, vision problems, leg amputations, and nerve damage. Objective : This research was conducted to analyze the risk factors associated with the incidence of Diabetes Mellitus in the UPT Puskesmas Parung Work Area. Methods: This research is an analytical study using a case control design. The sample cases in the study were respondents who were diabetes mellitus sufferers, namely 69 people and control samples was 6 people who were not diabete melitus sufferers. The sampling technique used in this study (total sampling) for the case group and simple random sampling for the control group. The results showed that there was a significant relationship between physical activity with the incidence of  diabetes mellitus (p value = 0,004; OR = 2,947 (95% CI 1.469-5.912)). Meanwhile smoking behavior and consumption of fruits and vegetables did not have  a significant relationship with the incidence of diabetes melitus (p value>0.05). Conclusion: Public health center officers need to maximize efforts to educate the case groups or control groups regarding risk factor control such as physical activity and consumption of fruits and vegetables
Hubungan umur, masa kerja dan kuliah online dengan produktifitas dosen pada masa pandemi covid-19 di Universitas “X” kota Semarang.
Authors: Asfawi Supriyono , Yuantari MG Catur , Manglapy Yusthin M , Pratama Yohanes , Hariono Rini Wulandari , Palupi Wening Wiworo
Published: May 2023

During the COVID-19 pandemic, the teaching and learning process must continue, work from home is one solution for its implementation. The obligation of lecturers to carry out the Tri Dharma of Higher Education must still be carried out as a benchmark for the success and productivity of lecturers. This study aims to see the level of productivity of lecturers during the covid-19 pandemic at the "X" university in Semarang city. The results show that lecturer productivity as measured by the Lecturer Workload (BKD) parameter is in the good category with the number of respondents for 29 lecturers (53%), the rest in the lesser category. But overall productivity is better during the pandemic.
Strategi Pengelolaan Limbah Padat Infeksius di Rumah Sakit Ibu dan Anak Family Jakarta Utara
Authors: Bria Yulius , Basriman Iman , Gusdini Ninin
Published: May 2023

The hospital is a health service that produces various infectious wastes that can endanger the officers who handle the waste and visitors and the community around the hospital. The purpose of the study was to determine the performance of infectious solid waste management at the Family Mother and Child Hospital, to determine the internal and external factors in the management of infectious solid waste at the Family Mother and Child Hospital, and to obtain the formulation of infectious solid waste management strategies at the Mother's Hospital. and Child Family. This research was conducted at the Mother and Child Family Hospital, North Jakarta, related to infectious solid waste management strategies. Data collection methods used are interviews, focus group discussions (FGD) and questionnaires. To get the main priority strategy using the IFE- EFE- IF- SWOT matrix. Research Results Based on the analysis of the QSPM matrix, there were 6 strategies that could be prioritized based on the highest ranking, namely (1) Implementing infectious solid waste management systems and procedures in a professional manner, (2) Improving the quality and competence of officers to prevent environmental pollution, (3) Conducting periodic socialization/training to employees related to infectious solid waste management, (4) Preparing medical waste management plans in accordance with the standards of the Minister of Health, (5) Providing sanctions to employees who do not follow the rules in handling infectious solid waste, (6) Optimizing the budget in infectious solid waste management.   Keywords: Infectious Solid Waste Management Strategy
Pengaruh Faktor Agent, Faktor Lingkungan Dan Faktor Pejamu Terhadap Jumlah Kasus Penyakit Tuberkulosis Di Era Pandemi Covid-19: Literatur Review
Authors: Sabata Lice , Triasfitri Riza
Published: May 2023

In 2019 WHO determined a Global Pandemic caused by Coronavirus disease (COVID-19) which was found as many as 118,000 cases in 110 countries. So that every country is advised to prevent the spread of COVID-19 and prepare efforts to handle the spread of COVID-19 (Khoirunisa, 2021). In its development, SARS-CoV-2 underwent mutations with various variants which are now the attention of all countries in the world (Adityo Susilo, 2022). In fact, during this time the disease that often attacks the respiratory tract and spreads quite quickly, one of which is caused by the bacteria Mycobacterium tuberculosis. Indonesia is ranked 3rd in the world with 91% TB cases, namely Banten, Gorontalo, DKI Jakarta, North Ulawesi, West Sulawesi. The purpose of this literature review is to find out what factors affect the number of tuberculosis cases in the COVID-19 pandemic based on research that has been carried out.Keywords: agent factor, environmental factor, Covid-19 and TB
KAJIAN FAKTOR UTAMA USER EXPERIENCE DAN USABILITY MAHASISWA DALAM MENGGUNAKAN SISTEM DESAIN FORMULIR ELEKTRONIK
Authors: Widianawati Evina , Setiono Oki , Wulan Widya Ratna , Wulandari Fitria
Published: May 2023

Rekam medis elektronik wajib diterapkan di seluruh fasilitas pelayanan kesehatan di Indonesia sesuai dengan Permenkes no 24 tahun 2022. Dalam prosesnya, institusi pendidikan turut mengembangan sistem rekam medis elektronik dalam membekali mahasiswa sebelum terjun ke duia kerja. Sistem desain formulir elektronik dirancang untuk implementasi pembelajaran matakuliah manajemen dan desain formulir di era digital. Penelitian ini bertujuan untuk mengkaji faktor utama yang mempengaruhi usability dan user experience mahasiswa dalam menggunakan sistem desain formular elektronik. Data diperoleh melalui kuesioner dengan skala linkert yang diisi oleh mahasiswa D3 rekam medis dan informasi kesehatan sebagai pemakai sistem sebanyak 104 mahasiswa. Teknik analisa data dengan menggunakan analisis faktor untuk mengetahui faktor utama yang mempengaruhi usability dan user experience mahasiswa. Hasil penelitian menunjukkan bahwa dalam hal usability faktor mudah diingat merupakan faktor utama yang mempengaruhi mahasiswa dalam menggunakan sistem, sedangkan faktor kepuasan kurang berpengaruh pada usability penggunaan sistem. Dalam hal user experience faktor daya tarik merupakan faktor utama mahasiswa dalam menggunakan sistem, sedangkan faktor kebaruan kurang berpengaruh pada user experience dalam penggunaan sistem. Untuk meningkatkan usability dan user experience mahasiswa maka sistem perlu ditingkatkan dalam hal kebaruan dan kepuasan dengan melakukan perbaikan agar sistem terlihat lebih menarik dan sesuai kebutuhan pengguna.
Hubungan Pekerjaan Orang Tua Dengan Stimulasi Dini Pada Anak Usia 0-36 Bulan diwilayah Kerja Puskesmas Bungo I Kabupaten Bungo
Authors: Arofah Suhaela , Fitriwati Citra Indah
Published: May 2023

The stages of development that must be passed by children, including language development, gross motor, fine motor and social. Cognitive and language disorders account for about 8% of developmental disorders in children caused by stimulation or parental communication patterns. Working mothers can have a positive or negative impact on child development. Based on data from the Central Bureau of Statistics, from 100% of women in Indonesia, 97.25% are working women, the remaining 2.74% women do not work.Objective: To determine the relationship between parents' work and early stimulation in children aged 0-36 months.The cross sectional research design is a form of non-experimental observational study research that is descriptive.Results: The group of parents who do not work as many as 13 people (73.9%), the group of parents who work as many as 6 people (26.1%). The respondent group received early stimulation as many as 14 people (60.9%), the respondent group did not get early stimulation 9 people (39.1%). The relationship between the variables of parents' work and early stimulation is that parents who do not work do not do early stimulation as many as 4 people and parents do not work to do early stimulation as many as 13 people. The job status of parents who work and do not do early stimulation is 2 people, doing early stimulation is 4 people.Conclusion: There is no relationship between maternal employment status with early stimulation,through the chi square statistical test p = 0.510.

Keywords: Toddler, Working Mother, Early Stimulation
Penerapan Terapi Bermain Mewarnai Gambar Dengan Pasir Warna Terhadap Kecemasan Anak Usia Pra Sekolah
Authors: Madepan Mulia  , Maulida Rizki Amalia  , Dewi Damayanti
Published: May 2023

Introduction: Anxiety of preschool children can be caused due to separation, feelings of loss, bodily injury and pain. The impact of this anxiety risks disrupting the child's growth development and the healing process. Efforts to reduce anxiety of preschool children can be done by giving playing therapy coloring pictures with colored sand. Useful Aim: This study aims to determine the anxiety of preschool children who experience hospitalization before and after being given playing therapy coloring pictures with colored sand in Rumah Sakit Ibu dan Anak (RSIA) Restu Bunda Bandar Lampung. Research Methods: The method in this study by giving playing therapy coloring pictures with colored sand for two participants preschool children children who experienced nursing problems due to hospitalization which were reported in the form of case studies. Results: The results obtained were a decrease in signs and symptoms of hallucinations and an increase in the patient's ability to cope with hallucinations. Suggestion: Nurses are expected to provide optimal application of play therapy coloring pictures with color sand to pre-school age children who experience anxiety nursing problems.
Penerapan Deep Back Massage dan Massage Endorphin Terhadap Kontrol Nyeri Kala I Pada Asuhan Keperawatan Intranatal Care
Authors: Amir Amir , Rantesigi Nirva
Published: May 2023

Pendahuluan: Persalinan diartikan sebagai suatu proses yang dimulai dengan adanya kondisi peregangan dan pelebaran mulut rahim akibat dari kontraksi uterus yang menyebabkan terjadinya dilatasi serviks yang dirasakan pada pembukaan 0-10 cm, terjadi peningkatan intensitas dan frekuensi kontraksi sehingga menyebabkan nyeri persalian. Pemberian teknik deep back massage dan massage endorphin merupakan salah satu penatalaksanaan keperawatan pada pasien intranatal care yang mengalami masalah nyeri kala 1 sebelum persalinan. Metode Penelitian: Dengan pendekatan studi kasus. Sampel penelitian 1 orang pasien intranatal care dengan kehamilan 37 sampai 40 minggu yang mengalami nyeri kala I sebelum persalinan. Penelitian dilakukan selama 3 hari dengan waktu pemberian ±30 menit untuk setiap kontraksi dan menggunakan alat ukur visual analog scale (VAS). Hasil: Setelah dilakukan implementasi selama 3 hari pada Ny.E dengan pemberian intervansi deep back massage dan massage endorphin  dengan durasi ±30 menit saat kontraksi dapat mengontrol dan beradaptasi dengan rasa nyeri kala 1 pada pasien intranatal care. Saran: Diharapkan perawat dapat memberikan intervensi ini sebagai pendamping terapi farmakologi untuk mengatasi masalah keperawatan nyeri kala 1 pada pasien intranatal care.
Penerapan Relaksasi Diaphragmatic Breathing Exercise Terhadap Dyspnea Pada Asuhan Keperawatn Pasien Penyakit Paru Obstruktif (PPOK)
Authors: Irawati Ni Putu Elsy
Published: May 2023

Introduction : Chronic obstructive pulmonary disease (COPD) is a condition in which the lungs experience obstruction that is not fully reversible. One of the independent nursing interventions in dealing with decreased is the diaphragmatic breathing exersice relaxation technique. This technique is a non-pharmacological therapy that can improve abdominal movement by reducing respiratory muscle activity. The purpose of the study was to determine the application of relaxation diaphragmatic breathing to dyspnea in the nursing care of patients with chronic obstructive pulmonary disease (COPD) in Poso Hospital. Research methods: descriptive with a case study approach. Results: obtained complaints of shotness of breath, breathing 27x/m, pulse 102x/m, blood pressure 130/90 mmHg with a diagnosis of ineffective breathing pattern, ineffective airway clearance and activity intolerance. Ventilation support interventions, airway management, and activity therapy. Implementation was carried out for 5 days. Evaluation after the implementation of the implementation of Diaphragmatic Breathing Exersice Relaxation there is change in Dyspnea in Mrs.B. Conclusion the application of Diaphragmatic Breathing Exersice Relaxation can overcome the problem of Dyspnea. Suggestion: are expected to provide nursing interventions to overcome existing nursing problems in Chronic Obstructive Pulmonary Disease (COPD) patients with dyspnea cases.
Analysis of diversity and antibiotic susceptibility profile of bacterial strains isolated from freshwater canal of Lahore, Pakistan
Authors: Malik Maimoona , Tanveer Sana , Ali Basharat
Published: May 2023

The key objective of current study was to analyse the bacterial diversity of canal water of Lahore, Pakistan. Members of Enterobacteriaceae were targeted that may pose serious health issues to human health.  Total 50 bacterial strains were isolated by using Eosin Methylene Blue agar and MacConkey agar. The 16S rRNA gene sequencing of 30 strains confirmed the final taxonomic status of bacterial strains. The results manifested that strains belong to genera of Enterobacter, Escherichia, Klebsiella, Pseudomonas, Acinetobacter, Aeromonas and Vogesella. Antibiotic susceptibility profile of isolates was evaluated against 13 different antibiotics. E. coli SCE-1 showed highest resistant against majority of the antibiotics. Whereas all strains were sensitive to Amikacin (30 µg). Aeromonas hydrophila SD-6 exhibited highest sensitivity against all antibiotics except ampicillin (10 µg) and amoxicillin (25 µg). None of the bacterial strain was completely resistant or susceptible to all antibiotics. Except E. coli all strains were sensitive to Amikacin (30 µg), Gentamycin (30 µg) and Norfloxacin (10 µg). Most of the strains showed intermediate and resistant antibiotic profile towards Nitrofurantoin (300 µg). Latex agglutination test was performed for the screening of E. coli O157 that showed negative results for this serotype. The detection of potential human pathogens like E. coli, Pseudomonas aeruginosa, Klebsiella pneumoniae and A. hydrphila in canal water indicates that it is not suitable for domestic purposes, recreational activities, and irrigation
Novel mechanisms of macrolide resistance revealed by in vitro selection and genome analysis in Mycoplasma pneumoniae
Authors: Wang Na , Xu Xiaogang , Xiao Li , Liu Yang
Published: May 2023

Mycoplasma pneumoniaeis an important pathogen causing upper and lower respiratory tract infections in children and other age groups. Macrolides are the recommended treatments of choice forM. pneumoniaeinfections. However, macrolide resistance inM. pneumoniaeis increasing worldwide, which complicates the treatment strategies. The mechanisms of macrolide resistance have been extensively studied focusing on the mutations in23S rRNAand ribosomal proteins. Since the secondary treatment choice for pediatric patients is very limited, we decided to look for potential new treatment strategies in macrolide drugs and investigate possible new mechanisms of resistance. We performed anin vitroselection of mutants resistant to five macrolides (erythromycin, roxithromycin, azithromycin, josamycin, and midecamycin) by inducing the parentM. pneumoniaestrain M129 with increasing concentrations of the drugs. The evolving cultures in every passage were tested for their antimicrobial susceptibilities to eight drugs and mutations known to be associated with macrolide resistance by PCR and sequencing. The final selected mutants were also analyzed by whole-genome sequencing. Results showed that roxithromycin is the drug that most easily induces resistance (at 0.25 mg/L, with two passages, 23 days), while with midecamycin it is most difficult (at 5.12 mg/L, with seven passages, 87 days). Point mutations C2617A/T, A2063G, or A2064C in domain V of23S rRNAwere detected in mutants resistant to the 14- and 15-membered macrolides, while A2067G/C was selected for the 16-membered macrolides. Single amino acid changes (G72R, G72V) in ribosomal protein L4 emerged during the induction by midecamycin. Genome sequencing identified sequence variations indnaK,rpoC,glpK,MPN449, and in one of thehsdS(MPN365) genes in the mutants. Mutants induced by the 14- or 15-membered macrolides were resistant to all macrolides, while those induced by the 16-membered macrolides (midecamycin and josamycin) remained susceptible to the 14- and 15-membered macrolides. In summary, these data demonstrated that midecamycin is less potent in inducing resistance than other macrolides, and the induced resistance is restrained to the 16-membered macrolides, suggesting a potential benefit of using midecamycin as a first treatment choice if the strain is susceptible.
Comparison of regional anesthetic techniques for postoperative analgesia after adult cardiac surgery: bayesian network meta-analysis
Authors: Zhou Ke , Li Dongyu , Song Guang
Published: May 2023

Background

Patients usually suffer acute pain after cardiac surgery. Numerous regional anesthetic techniques have been used for those patients under general anesthesia. The most effective regional anesthetic technique was still unclear.

Methods

Five databases were searched, including PubMed, MEDLINE, Embase, ClinicalTrials.gov, and Cochrane Library. The efficiency outcomes were pain scores, cumulative morphine consumption, and the need for rescue analgesia in this Bayesian analysis. Postoperative nausea, vomiting and pruritus were safety outcomes. Functional outcomes included the time to tracheal extubation, ICU stay, hospital stay, and mortality.

Results

This meta-analysis included 65 randomized controlled trials involving 5,013 patients. Eight regional anesthetic techniques were involved, including thoracic epidural analgesia (TEA), erector spinae plane block, and transversus thoracic muscle plane block. Compared to controls (who have not received regional anesthetic techniques), TEA reduced the pain scores at 6, 12, 24 and 48 h both at rest and cough, decreased the rate of need for rescue analgesia (OR = 0.10, 95% CI: 0.016–0.55), shortened the time to tracheal extubation (MD = −181.55, 95% CI: −243.05 to −121.33) and the duration of hospital stay (MD = −0.73, 95% CI: −1.22 to −0.24). Erector spinae plane block reduced the pain score 6 h at rest and the risk of pruritus, shortened the duration of ICU stay compared to controls. Transversus thoracic muscle plane block reduced the pain scores 6 and 12 h at rest compared to controls. The cumulative morphine consumption of each technique was similar at 24, 48 h. Other outcomes were also similar among these regional anesthetic techniques.

Conclusions

TEA seems the most effective regional postoperative anesthesia for patients after cardiac surgery by reducing the pain scores and decreasing the rate of need for rescue analgesia.

Systematic Review Registration

https://www.crd.york.ac.uk/prospero/, ID: CRD42021276645
FAST technique: fast atrial sheath traction technique for device closure of atrial septal defects
Authors: Haddad Raymond N. , Kaddoura Rachid , Kasem Mohamed , Alsoufi Mahmoud
Published: May 2023

Background

Transcatheter closure of atrial septal defects (ASDs) is well-established. However, this procedure can be challenging, requiring multiple attempts and advanced implantation maneuvers.

Materials and methods

From July 2019 to July 2022, patients to whom the fast atrial sheath traction (FAST) technique was applied for ASD device closure were prospectively followed up. The device was rapidly unsheathed in the middle of the left atrium (LA) to let it clamp the ASD from both sides simultaneously. This novel technique was directly applied in patients with absent aortic rims and/or ASD size-to-body weight ratio higher than 0.9 or after failed attempts of standard implantation.

Results

Seventeen patients (64.7% males) were involved with a median age of 9.8 years [interquartile range (IQR), 7.6–15.1] and a median weight of 34 kg (IQR, 22–44). The median ASD size on ultrasound was 19 mm (IQR, 16–22). Five (29.4%) patients had absent aortic rims, and three (17.6%) patients had an ASD size-to-body weight ratio higher than 0.9. The median device size was 22 mm (IQR, 17–24). The median difference between device size and ASD two-dimensional static diameter was 3 mm (IQR, 1–3). All interventions were straightforward without any complications using three different occluder devices. One device was removed before release and upsized to the next size. The median fluoroscopy time was 4.1 min (IQR, 3.6–4.6). All patients were discharged the next postoperative day. On a median follow-up of 13 months (IQR, 8–13), no complications were detected. All patients achieved full clinical recovery with complete shunt closure.

Conclusion

We present a new implantation technique to efficiently close simple and complex ASDs. The FAST technique can be of benefit in overcoming left disc malalignment to the septum in defects with absent aortic rims and in avoiding complex implantation maneuvers and the risks of injuring the pulmonary veins.
Exercise intervention improves mitochondrial quality in non-alcoholic fatty liver disease zebrafish
Authors: Zou Yun-Yi , Tang Xiang-bin , Chen Zhang-Lin , Liu Bin , Zheng Lan , Song Ming-Yang , Xiao Qin , Zhou Zuo-Qiong , Peng Xi-Yang , Tang Chang-Fa
Published: May 2023

Introduction

Recent reports indicate that mitochondrial quality decreases during non-alcoholic fatty liver disease (NAFLD) progression, and targeting the mitochondria may be a possible treatment for NAFLD. Exercise can effectively slow NAFLD progression or treat NAFLD. However, the effect of exercise on mitochondrial quality in NAFLD has not yet been established.

Methods

In the present study, we fed zebrafish a high-fat diet to model NAFLD, and subjected the zebrafish to swimming exercise.

Results

After 12 weeks, swimming exercise significantly reduced high-fat diet-induced liver injury, and reduced inflammation and fibrosis markers. Swimming exercise improved mitochondrial morphology and dynamics, inducing upregulation of optic atrophy 1(OPA1), dynamin related protein 1 (DRP1), and mitofusin 2 (MFN2) protein expression. Swimming exercise also activated mitochondrial biogenesis via the sirtuin 1 (SIRT1)/ AMP-activated protein kinase (AMPK)/ PPARgamma coactivator 1 alpha (PGC1α) pathway, and improved the mRNA expression of genes related to mitochondrial fatty acid oxidation and oxidative phosphorylation. Furthermore, we find that mitophagy was suppressed in NAFLD zebrafish liver with the decreased numbers of mitophagosomes, the inhibition of PTEN-induced kinase 1 (PINK1) – parkin RBR E3 ubiquitin protein ligase (PARKIN) pathway and upregulation of sequestosome 1 (P62) expression. Notably, swimming exercise partially recovered number of mitophagosomes, which was associated with upregulated PARKIN expression and decreased p62 expression.

Discussion

These results demonstrate that swimming exercise could alleviate the effects of NAFLD on the mitochondria, suggesting that exercise may be beneficial for treating NAFLD.
Cross-sectional and longitudinal comparison of health-related quality of life and mental well-being between persons with and without post COVID-19 condition
Authors: Scott Emily Stella , Lubetkin Erica I. , Janssen Mathieu F. , Yfantopolous John , Bonsel Gouke J. , Haagsma Juanita A.
Published: May 2023

Background

Still little is known about the impact of post COVID-19 condition (PC) on health-related quality of life (HRQOL) and mental well-being. We compared participants with PC with three groups: an acute COVID-19 infection (AC) only, at least one chronic condition (CC) but no COVID-19, or no condition at all, healthy (PH). Between these disease groups, we also estimated and compared HRQOL and mental well-being change over time.

Methods

Participants from six countries (Greece, Italy, Netherlands, Sweden, United Kingdom and United States) completed two web-based questionnaires (T1 = April–May 2020 and T2 = April–June 2022). Primary outcomes were HRQOL, measured by EQ-5D-5L and EQ VAS, and mental well-being (measured by World Health Organisation-Five (WHO-5) Well-Being Index, Patient Health Questionnaire (PHQ)-9 and General Anxiety Disorder (GAD)-7). All analyses were stratified by the disease groups.

Results

In total, 4,999 participants filled out both surveys: 240 were in PC, 107 in AC, 1798 in CC and 2,854 in PH. At T2, the mean EQ-5D-5L index values for the PC, AC, CC and PH groups were 0.70, 0.73, 0.75 and 0.92 (p < .001), respectively. Mean EQ VAS scores were 66, 65, 68 and 81 (p < .001), respectively. Poor mental well-being, depression and anxiety mean values were highest in the PC group (47.7; 9.1; 7.4), followed by the AC group (51.1; 7.7; 5.7), CC group (56.1; 5.2; 4.2) and the PH group (65.6; 2.8; 2.5), respectively (p < .001 between groups). Over time, HRQOL deteriorated in all groups, apart from the PH group. We observed the largest deterioration in the CC (EQ-5D-5L index: Δ0.03, p < .001) and AC group (EQ VAS: Δ6.3, p < .001). For the mental well-being outcomes, deterioration for WHO-5 and PHQ-9 were largest in the AC group (Δ4.8, p = .016; Δ-1.3, p = .012). Rates for GAD-7 improved for the PH and CC groups (PH: Δ1.27, CC: Δ0.56, p < .001).

Conclusions

In the cross-sectional analysis, participants with PC had the worst HRQOL and mental well-being compared to the other groups. In terms of change since the start of the COVID-19 pandemic, HRQOL and mental well-being deterioration was highest among AC participants and had a lower impact among PC participants, most likely due to pre-existing chronic disease.