bluuebunny/crossref_metadata_2025 huggingface dataset:
investigação sobre as concepções de letramento financeiro de professores de Matemática em três cidades com o suporte do CHIC
Authors: Souza Fabiano dos Santos , Vieira Tiago Vanini , Junior Marco Aurélio Kistemann
Published: September 2021

Neste artigo averíguam-se as características do processo de formação inicial e atuação de 27 professores de matemática de educação básica quanto à educação financeira e o letramento. Os dados obtidos foram por meio de um questionário contendo 27 questões fechadas e 14 abertas, que foram analisados utilizando-se a metodologia de análise de similaridade com o suporte do software CHIC (Classificação Hierárquica, Implicativa e Coesitiva). No que tange especificamente à formação dos professores, em relação à educação financeira, há indícios que ocorreu de forma superficial. A análise também evidencia o fato de que a educação financeira ainda é muito confundida com a matemática financeira, sendo abordada em sala de aula de maneira muito superficial, apenas com conceitos básicos, sem a promoção da construção do letramento e consciência financeira dos alunos. Defende-se uma formação em serviço aos educadores matemáticos, com temáticas relacionadas à educação financeira escolar de acordo com as diretrizes da Estratégia Nacional de Educação Financeira (ENEF) e das orientações da Base Nacional Comum Curricular Brasileira (BNCC).
uso da sala de aula invertida no ensino superior: preenchendo lacunas em conteúdos de matemática elementar
Authors: Nachtigall Cícero , Alves Rozane da Silveira
Published: September 2021

Este estudo investigou como as principais características atribuídas à metodologia da sala de aula invertida – tais como personalização do ensino, autonomia do discente, interação professor/aluno e aluno/aluno e melhora na aprendizagem – foram identificadas pelos participantes de um curso de curta duração oferecido por um projeto de ensino de uma universidade federal do sul do Brasil. Foram confeccionados e disponibilizados 33 vídeos pedagógicos que abordavam integralmente o conteúdo do módulo de matemática básica, que habitualmente era oferecido pelo projeto na modalidade presencial. Os vídeos correspondentes a cada aula invertida foram enviados aos participantes da pesquisa com antecedência, e os respectivos encontros presenciais foram direcionados para o esclarecimento de dúvidas e aplicação dos conteúdos abordados nos vídeos. Os sujeitos desta pesquisa foram 35 estudantes de graduação e os instrumentos de coleta de dados foram entrevistas, analisados qualitativamente através da técnica de análise de conteúdo, além de questionários e observações. Os estudantes manifestaram ter identificado maior personalização do ensino, acréscimo de autonomia e de qualidade na aprendizagem, qualificação da interação entre professor e aluno e na interação entre pares nas aulas em que a metodologia da sala de aula invertida foi adotada, em comparação com as aulas expositivas tradicionais. Esta foi a primeira experiência do referido projeto com o ensino híbrido, e a maioria dos estudantes participantes da pesquisa relatou não possuir experiências prévias com a metodologia da sala de aula invertida. Este trabalho é parte de uma dissertação de mestrado apresentada no programa de Pós-Graduação em Educação Matemática (PPGEMAT/IFM) em fevereiro de 2020.
The Story of Moses and Pharaoh in a Structural Anthropology Approach
Authors: Aufi Ahmad Umam
Published: September 2021

This study examined the story of Moses and Pharaoh as one of the Islamic narrative discourses in the Qur’an. Structural anthropology Claude Lévi-Strauss was used to analyze the story’s structure or nature of the mind. The results of the study explicate that the story of Moses and Pharaoh had a structure of “struggle plot to convey the truth”. Based on the episodes of the story showed a continuous transformation of structure and forms cylindrical triangle. Behind the story of Moses and Pharaoh was reflection of the developing culture in Islamic societies. First, there were some societies’ components in the struggle process of the faithful in conveying the truth, both theologically or socio-politically. Such as the actor of social change (Moses), masses of people (the people of Moses), authorities who refused the change (Pharaoh and his leaders) and opportunist intellectuals (the magicians before being defeated by Moses), and organic intellectuals (the magicians after believing in the truth of Moses). Second, the community’s culture was controlled by established authorities, the commitment of the truth will gain a refusal and despite resistance. The prerequisite to be able to undergo it was to confirm it rationally and empirically (according to the times).
Siradjuddin Abbas’ Contribution in the Study of Hadith in Indonesia
Authors: Karnedi Rozian
Published: September 2021

This research was proposed by Siradjuddin Abbas who in some literature is not known as a hadith figure. He is better known as a prominent Indonesian theologian and fiqh expert. In fact, the thoughts and contributions of Siradjuddin Abbas in the study of hadith can be traced in his various works. This study aimed to reveal the contribution of Siradjuddin Abbas in the study of hadith. The descriptive-analytical method and the biographical approach were used to answer the questions: 1) whether Siradjuddin Abbas can be said to be a hadith figure, and 2) what is the contribution of Siradjuddin Abbas in the study of hadith in Indonesia. The results of the study indicated that; 1) Siradjuddin Abbas is not only a theologian and fuqahā’ but also a figure in Indonesian hadith. Although he did not write a specific hadith book, Siradjuddin Abbas’s thoughts on hadith are scattered in his various works. He was a collector, commentator and eristic of hadith in written and oral. 2) The roles and thoughts of Siradjuddin Abbas contributed to the study of hadith in Indonesia. He strengthens the argument for Ahlussunnah wal Jamā’ah’s understanding by providing hadith arguments on the thoughts of kalam and fiqh. Although the role, thought and understanding of the Hadith of Siradjuddin Abbas is more of a defence of the Asy’ariyah theology and the Shafi’i school, the thought of the hadith becomes a reference and guide for the Islamic community, especially from traditionalist Muslims
Pertussis treatment strategies
Authors: Ivanchenko N.
Published: September 2021

Whooping cough, despite the fact that the disease has long been known, still remains a problem for all countries. Cough attacks can cause not only physical discomfort to the patient, but also a significant negative psycho-emotional load. Existing drug therapy to date does not solve all the problems in the treatment of whooping cough. The aim of our study was to conduct a literature review of pertussis treatment and evaluate the efficacy of inhaled corticosteroids in adult patients with moderate to severe disease.Material and methods. Guidelines for the treatment of whooping cough were studied, and 26 medical records of inpatients with the diagnosis of “Pertussis” were analysed. Conclusion. Antibiotic therapy is a mandatory component of treatment. The effectiveness of inhaled corticosteroids in adult patients with moderate to severe whooping cough has been established.
Nasionalisme Tenaga Kerja Indonesia (TKI) Di Malaysia dalam Narasi Media Sosial
Authors: Maksum Ali , Surwandono Surwandono
Published: September 2021

This article discusses the nationalism sentiment among Indonesian migrant workers in Malaysia from the social media narratives. The aims of this article are (1) to examine the framing of nationalism among Indonesian migrant workers in Malaysia; (2) to understand the typology of nationalism among Indonesian migrant workers in Malaysia; and (3) to examine the influences factors behind the nasionalism among Indonesian migrant workers in Malaysia. This is qualitative analysis sumplemented by structured interview as well as focus group discussion (FGD). The systematic content analysis on some particular documents is also applied in this study.
Information Literacy of a Foreign Language Teacher: An Analysis of Russian and European Professional Standards of Teachers
Authors:   NRU MPEI, Slepneva Marina A.
Published: September 2021

The introduction of information and communication technologies into the educational process began more than twenty years ago, along with the rapid spreading of computers around the world. However, not all educational institutions have supported the inclusion of information and communication technologies into the educational process for the above-mentioned quite a long period of time. Most likely, this was due to insufficient financial investments in modernization. In addition, insufficient attention was initially paid to training of teachers for working with digital technologies. At present, when information and communication competence has already been included into all international standards for teachers, it turned out that neither graduates from teacher training institutes nor teachers who have been working for already a long period of time have sufficient competencies for using digital technologies in practice. A comparative analysis of Russian and European professional standards for teachers is carried out, and the competencies they should possess are considered. Various versions of the information literacy definitions are given, which have undergone changes in the technological development process. Special attention is paid to the requirements for competencies of foreign language teachers in the field of digital technologies. The list of the currently available digital tools, including mobile devices, is discussed. The students actively use such technologies to learn languages, but to yield a really positive effect, digital tools should be integrated directly into the educational process in a professional manner. The experience of work with digital technologies gained by the teachers of the NRU MPEI Department of Foreign Languages is considered. A conclusion has been drawn, according to which a high level of information literacy enables teachers not only to change their own pedagogical methods, but also to open new horizons for their students, who, in turn, gain access to high quality education.
Five-Phase Converter Control Algorithms for Implementing Space-Vector Modulation
Authors:   Ufa State Aviation Technical University, Tereshkin Vladimir M. , Grishin Dmitriy A. ,   LLC «Gaz-Project-Engineering», Tereshkin Vyacheslav V. ,   Ufa State Aviation Technical University, Balgazin Iskander I. ,   Ufa State Aviation Technical University
Published: September 2021

Multiphase (five-phase) motors can be considered as an alternative to three-phase motors in implementing electric traction with vector control. The subject of the study is the five-phase winding voltage vector space formed by various control algorithms of a five-phase converter. Thirty logical states of the converter form three types of the vector voltage space of a symmetrical five-phase winding. Each of the vector space types forms the resulting vector of a certain value. The resulting (generalized) voltage vector can take three different values. With the phase time sequence ABCDE of a symmetrical five-phase winding ABCDE with the spatial phase shift equal to 72 electrical degrees, the fundamental harmonic vector is the resulting working voltage vector. With the phase time sequence ACEBD of a symmetrical five-phase winding ABCDE with the spatial phase shift equal to 72 electrical degrees, the resulting voltage vector of the third harmonic is the resulting working vector. The rotation frequency of the resulting third harmonic vector is three times the rotation frequency of the fundamental harmonic vector, and the rotation direction is opposite to the rotation direction of the fundamental harmonic vector. With one of the phase voltage forms and the phase time sequence ACEBD, the modulus of the resulting voltage vector of the third harmonic component is equal to the modulus of the resulting vector of the fundamental harmonic component. There are two converter control algorithms that form the resulting voltage vectors that are equal in modulus, but with different rotation speeds multiple of three. An approach to studying the multiphase phase winding voltage vector space has been elaborated, which can be applied in implementing vector control.
La familia y la política según Aristóteles
Authors:   Universidad de San Martín de Porres, Perú, Leuridan Huys Johan
Published: September 2021

Aristóteles señala la importancia de la familia para los asuntos políticos. Encontramos frases contradictorias que afirman la prioridad o la bondad de la familia o la bondad de la política. Los seres humanos se desarrollan en la polis, pero la familia tiene su autonomía propia para la educación en valores éticos a través del amor familiar y de pertenencia. La mayor ventaja es la amistad por medio de la cual se aprende en familia, y con los conflictos civiles disminuirán. Los líderes políticos necesitan la capacidad de gobernar y virtud moral. La relación entre un hombre y una mujer es agradable cuando ambos mantienen su dignidad.
Application of High Hydrostatic Pressure (HHP) to Improve Cryopreservation of Young Bull Semen
Authors: Szczęśniak-Fabiańczyk Barbara , Gogol Piotr , Gajda Lechosław , Smorąg Zdzisław
Published: September 2021

The objective of the study was to determine the effect of high hydrostatic pressure (HHP) on quality of cryopreserved semen of young bulls. Semen for this study was collected from 8 bulls aged between 13 and 18 months at monthly intervals, from June to September. After collection, semen was diluted in a commercial Bioxcell® extender (one part at 1:1 and a second part to give a sperm concentration of 20 million/0.2 mL), filled into straws and treated with HHP at 30 MPa for 90 min. After HHP treatment, pre-diluted semen (1:1) was diluted to a sperm concentration 20 million/0.2 mL and filled into straws. In addition, part of the semen diluted to a concentration of 20 million/0.2 mL was not treated with HHP (control). All of it was held at +4°C and frozen in a freezer after 2.5-h equilibration. Semen was thawed in a water bath at 38°C and subjected to estimation of the percentage of motile sperm both subjectively and using a computer-assisted semen analyzer and cytometric assessment of sperm cell membrane integrity. Subjective motility and fast progressive motility were significantly higher with pre-diluted (1:1) and HHP treated semen compared to control (P<0.05). No significant differences were observed in percentage of membraneintact spermatozoa between control and experimental groups. Additionally, the influence of HHP on the sperm of individual bulls was assessed. In bull number 2, the HHP treatment after semen pre-dilution significantly improved progressive motility from 54.1 to 63.4 percent (P<0.05). In bull number 4, the HHP treatment after semen pre-dilution significantly improved subjective motility, rapid motility and progressive motility by 12.5, 16.8 and 16.3 percent, respectively (P<0.05). No effect was seen for 6 bulls. It is concluded that for some bulls, the application of HHP before semen freezing may improve the cryopreservation outcome. However, this requires further research in this area, also to determine the fertilizing capacity of bull semen exposed to high hydrostatic pressure.
An Introduction to the Special Issue on Numerical Techniques Meet with OR - Part II
Authors: Gürbüz Burcu , Weber Gerhard-Wilhelm
Published: September 2021

The special issue: “Numerical Techniques Meet with OR” of the Foundations of Computing and Decision Sciences consists of two parts which are of the main theme of numerical techniques and their applications in multi-disciplinary areas. The first part of this special issue was already collected in the FCDS Vol. 46, issue 1. In this second part of our special issue editorial, a description of the special issue presents numerical methods which can be used as alternative techniques for Scientific Computing and led Operational Research applications in many fields for further investigation.
Some New Characterizations of The Harmonic and Harmonic 1-Type Curves in Euclidean 3-Space
Authors: Samanci Hatice Kuşak , Ayaz Sedat , Kocayiğit Huseyin
Published: September 2021

A Laplace operator and harmonic curve have very important uses in various engineering science such as quantum mechanics, wave propagation, diffusion equation for heat, and fluid flow. Additionally, the differential equation characterizations of the harmonic curves play an important role in estimating the geometric properties of these curves. Hence, this paper proposes to compute some new differential equation characterizations of the harmonic curves in Euclidean 3-space by using an alternative frame named the N-Bishop frame. Firstly, we investigated some new differential equation characterizations of the space curves due to the N-Bishop frame. Secondly, we firstly introduced some new space curves which have the harmonic and harmonic 1-type vectors due to alternative frame N-Bishop frame. Finally, we compute new differential equation characterizations using the N-Bishop Darboux and normal Darboux vectors. Thus, using these differential equation characterizations we have proved in which conditions the curve indicates a helix.
Traditional Chinese medicine in the treatment of high incidence diseases in cold areas: the thrombotic diseases
Authors: Tang Xueqing , Liu Xin , Mikaye Monayo Seth , Zhao Hongrui , Zhang Yong
Published: September 2021

Thrombotic diseases are the leading causes of death worldwide, especially in cold climates. Traditional Chinese medicine (TCM)-based therapies have gained increasing popularity worldwide, but also raised some concerns about its efficacy, safety profile and exact mechanisms. TCM has been traditionally used in the management of thrombosis and convincingly proven effective in modifying thrombosis progression, particularly the platelet function, coagulation system and fibrinolytic system. This review article focuses on TCM regulation of thrombosis with brief discussion on the fundamental aspects and relevant background information for better understanding of the subject. In addition to its antithrombotic effects, we will dive insight into the cellular and molecular mechanisms of TCM as pharmacological regulators of platelet aggregation, coagulation, and fibrinolysis. With increasing awareness and understanding of the benefits and potentials of TCM, TCM products will in no doubt gain its broader applications in the treatment of thrombosis and associated disorders, which in turn will deepen our understanding of its pharmacological and molecular mechanisms. Finally, current review provides a perspective view on the future directions to TCM research on thrombosis.
Tridepsides from the endophytic fungus colletotrichum gloeosporioides associated with a toxic medicinal plant tylophora ovata
Authors: Sun Sen-Feng , Zhu Shao , Cao Hai-Yan , Liu Yun-Bao , Yu Shi-Shan
Published: September 2021

Introduction

Bioactive secondary metabolites from the microbes living in frigid, toxic or other extreme environments are emerging as a new medicinal resource. Here, we report the discovery of new antidiabetic and anti-inflammatory compounds with novel structures from endophytic fungi hosted toxic medicinal plant.

Methods

The endophytic fungus isolated from toxic plants was fermented and extracted. The obtained extracts were purified with preparative HPLC to yield pure compounds. The purified compounds were examined by PTP1b inhibition and NO inhibition assays to evaluate their bioactivities.

Results

One new tridepsides (Compound 1), one new benzeneacetic acid derivative (Compound 3) and five known compounds (Compounds 2 and 4-7) were isolated from the ethyl acetate extract of Colletotrichum gloeosporioides, an endophytic fungus obtained from a toxic medicinal plant Tylophora ovata. Their structures were determined by spectroscopic data (1D and 2D NMR, HRESIMS) analyses. Compound 2 showed significant inhibitory activity against PTP1b with an IC50 value of 0.84 μM. Compounds 2 and 3 exhibited moderate inhibitory activities against the NO (nitric oxide) release in LPS-induced RAW 264.7 cells at 10 μM with percent inhibition of 39% and 33%, respectively.

Conclusion

The Compound 2 has potent PTP1b inhibitory effect indicating its antidiabetic potential and thus might be considered a lead compound for antidiabetic drug development.
Ablation of apoptosis-stimulating of p53 protein 1 protects mice from acute hepatic injury and dysfunction via NF-κB pathway in CCl4-induced hepatotoxicity
Authors: Daba Tolessa Muleta , Huang Xiang , Yagudin Timur , Yang Ying , Wang Jiangang , Fu Xiaoyu , Zhao Yue , Gao Haiyu , Zhou Yang , Pan Zhenwei , Zhong Xiangyu
Published: September 2021

Acute liver injury (ALI) is characterized by apoptosis, inflammation, and oxidative stress, and pathogenic mechanism of ALI is poorly understood. Apoptosis-stimulating of p53 protein 1 (ASPP1) is involved in environmental responses, tumor growth, and NF-KB activity, which is of critical importance to ALI. However, the role of ASPP1 in ALI remains largely unexplored. The current study aimed to determine the role of ASPP1 in ALI induced by CCl4 and the underlying mechanism. ASPP1 expression was detected in wild type (WT) mice with ALI induced by CCl4. The function of ASPP1 in ALI induced by CCl4 was investigated using conventional knockout ASPP1 mice. ASPP1 expression significantly increased in ALI mice at 24 hours after CCl4 injection. Deletion of ASSP1 ameliorated apoptosis, inflammation, and necrosis in ALI relative to WT mice. In addition, deficiency of ASPP1 improved liver flood flow as well as ALT and AST levels. The levels of phosphorylated p65 and phosphorylated IκBα were lower in ASPP1-/- mice than in WT mice with ALI. These results implicate that deletion of ASPP1 may act via inhibition of the NF-κB pathway and protect mice from ALI, which may be a new potential therapeutic target for the treatment of ALI.
The Safety Profile of the Anesthetic Effect of Alfaxalone and its Interaction with Xylazine and Ketamine in Chick’s Model (Gallus Gallus Domesticus)
Authors: Alatrushi Amjed Najem , Naser Ahmed Salah
Published: September 2021

The objective of our research was to estimate the therapeutic index and assess the interaction of alfaxalone (IP) with ketamine or xylazine (IM) in chicks by using isobolographic analysis. The up-and-down technique was involved to calculate the median effective anesthetic dosages (ED50) of alfaxalone, xylazine, and ketamine given separately or at the same time in young chicks. Then the up-and-down technique was involved to estimate the median lethal dosage (LD50) of alfaxalone (IP) to determine the safety profile. The ED50 of all anesthetics was evaluated isobolographically to assess the type of interaction between alfaxalone and xylazine or alfaxalone and ketamine. The alfaxalone ED50 was 32.88 mg/kg (IP), whereas the LD50 was 102.40 mg/kg (IP). The ED50 values for alfaxalone, ketamine, and xylazine were 32.88, 12.24, and 2.45 mg/kg, respectively. The ED50 values of alfaxalone with ketamine or xylazine (25:25 ED50 values) were: 7.39+2.35, and 8.61+0.63 mg/kg, respectively. ED50 values were decreased when the combinations of alfaxalone/ketamine or alfaxalone/xylazine were administered by 22-21% and 26-25%, respectively. The anesthesia of chicks with alfaxalone is safe, produces a surgical stage of anesthesia, and can be used for minor surgical procedures. The use of alfaxalone with ketamine or xylazine has been shown to have a synergistic effect and these findings may be of clinical relevance in poultry or may be extended to mammals following further clinical trials.
Preparation and quality evaluation of carbonated guava fruit drinks produced from BARI Payera-4
Authors: Wazed Md. Abdul , Gupta Mohim Das , Dey Shamor kanti , Majumder Rahul Kumar , Amina Al , Shakib Shabadur Rashid
Published: September 2021

The present study was conducted with the objective of utilizing new varieties of guava (BAARI Payera-4) fruit in the production of carbonated drinks and also evaluation of different properties such as physico-chemical and sensory characteristics with respect to the different guava juice concentrations (10%, 15%, and 20% of juice) and TSS (10°, 12° and 15° Brix), respectively. This variety is selected for the preparation of carbonated fruit drinks because of its refreshing acidic taste, seedless with good keeping quality and also delicious fruit with good aroma. The extracted fruit juice subjected to carbonation. The physicochemical factors such as viscosity, TSS, acidity, pH, color, ascorbic acid, volume of CO2 and sugars were studied and the changes were observed. The sensory evaluation study was done with hedonic scale to find the best combination of juice concentration and TSS. The obtained results of physiochemical parameters showed that guava juice level at 20% with 12°Bx (Sample T6) had received highest ascorbic acid 28.87 mg/100g, high acidity 0.51%, high color value ΔE 4.60 and highest volume of CO2. Data also revealed that sample T6 found to be superior among all with respect to sensory qualities such as color, flavor, appearance, taste and overall acceptability. In conclusion, the overall assessment pointed that the resulting carbonated drinks developed from BARI Payera-4, sample T6 was best for all physicochemical characteristics and, in general, resulted in good sensory behavior, indicating that it could be a promising alternative to synthetic soft drinks.
The Impact of Seven Macroprudential Policy Instruments on Financial Stability in Six Euro Area Economies
Authors: Lorenčič Eva , Festić Mejra
Published: September 2021

The aim of this paper is to investigate whether macroprudential policy instruments can influence the credit growth rate and hence financial stability. We use a fixed effects panel regression model to test the following hypothesis for six euro area economies (Austria, Finland, Germany, Italy, Netherlands and Spain) during time span 2010 Q3 to 2018 Q4: “Macroprudential policy instruments (degree of maturity mismatch; interbank loans as a percentage of total loans; leverage ratio; non-deposit funding as a percentage of total funding; loan-to-value ratio; loan-to-deposit ratio; solvency ratio) enhance financial stability, as measured by credit growth”. Our empirical results suggest that the degree of maturity mismatch, non-deposit funding as a percentage of total funding, loan-to-value ratio and loan-to-deposit ratio exhibit the predicted impact on the credit growth rate and therefore on financial stability. On the other hand, interbank loans as a percentage of total loans, leverage ratio, and solvency ratio do not exhibit the expected impact on the response variable. Since only four regressors (out of seven) have the signs predicted by our hypothesis, we can only partly confirm it.
Measuring monetary policy by money supply and interest rate: evidence from emerging economies
Authors: Bui Trung Thanh , Gábor Kiss Dávid
Published: September 2021

Although measuring monetary policy is a contentious issue in the literature, much less evidence on this issue is available for emerging economies. This paper aims to investigate the role of interest rate and money supply in measuring monetary policy in twelve emerging economies that target inflation through the analysis of Granger causality, impulse response function, and forecast error variance decomposition. The empirical results show that both money supply and interest rate are useful predictors for changes in inflation. Moreover, both show a comparable power to explain the variation of inflation. However, a rise in interest rate increases rather than decreases inflation, whereas money supply has a positive and expected effect on inflation. These findings suggest that interest rate may not fully capture the overall stance of monetary policy or interest rate has a limited effect on inflation.
Pengembangan Potensi Atraksi Wisata Seni Suara dan Musik di Kampoeng Wisata Titik Nol Jateng, Desa Bligo, Magelang
Authors: Lephen Purwanto , Raharja Budi , Hilmi Mahdi Naufal
Published: September 2021

Kampoeng Wisata Titik Nol Jateng di Blaburan, Bligo, Ngluwar, Magelang, Jawa Tengah memiliki peluang untuk berkembang sebagai desa wisata minat khusus, olah raga, wisata edukasi, dan budaya di perbatasan Jawa Tengah dan Yogyakarta. Potensi wisata tersebut perlu dikembangkan dengan memberdayakan anak-anak dan remaja bermain musik dan berseni suara. Motode pemberdayaan dan pengembangan dilakukan dengan observasi, pendataan, pengklasifikasian, wawancara, dan uji kemampuan menyanyi dan bermusik. Sesudah data peserta pembinaan seni suara dan musik dihimpun, dilakukan uji kepercayaan diri tampil di depan umum. Selanjutnya dilaksanakan pengembangan sumber daya manusia yang berminat pada penguatan bakat menyanyi dan bermusik hingga mampu tampil di depan umum. Pelatihan diikuti 65 peserta dari berbagai desa. Materi yang diajarkan: menyanyi (seni suara) dan seni musik sehingga dapat dibuat atraksi wisata menyanyi lagu anak, lagu remaja, lagu Korea, dan menyanyi bersama (koor), baik lagu pop Jawa maupun Indonesia dan Korea. Bakat-bakat penyanyi dan bermusik di Desa Bligo tersebut dapat memperkuat atraksi wisata musik dan seni suara di Kampoeng Wisata Titik Nol Jateng yang pada tahun 2018-2019 sebanyak 12.100 pengunjung atau rata-rata 500 orang per bulan. Atraksi wisata saat istirahat atau makan biasanya belum ada hiburan. Potensi anak-anak dan remaja dalam bidang musik dan seni suara akan memperkaya atraksi wisata di tepi Sungai Krasak tersebut dapat menyejahterakan warga setempat.
Analyzing smartphone innovative development: Evidence from Apple’s iPhone
Authors: VARSHAVSKII Aleksandr E. , KUZNETSOVA Mariya S.
Published: September 2021

Subject. We analyze development trends in iPhone by reviewing the way their key technological and economic indicators change.
Objectives. We trace patterns and trends in technological and economic indicators of iPhone, correlations of the indicators, and the dependence of the price and SAR on technological indicators.
Methods. Following our methodology, we study and model indicators of smartphones.
Results. We traced and determined the correlation of technological and economic indicators of iPhone. The article demonstrates how the price and SAR mainly depend on technological indicators of smartphones.
Conclusions and Relevance. As the findings show, as the above smartphone gets more technologically sophisticated, i.e. the price and SAR increase, we can expect higher risks for the man and the environment, though the mobile device development trends may still persevere. As seen from the analysis, SAR increases as smartphones have more cores and processor frequency, operation memory, which basically entails higher prices. In the mean time, the above indicators lower as the smartphone dimensions grow (screen diagonal, weight, battery capacity).
MARKETING OF HEALTHCARE ORGANIZATIONS: TOOLS FOR ATTRACTING AND RETAINING PATIENTS
Authors:   Research Institute of Healthcare Organization and Medical Management, Moscow Healthcare Department, Moscow, Russian Federation, AKSYONOVA E.I. , ZUDIN A.B. ,   N.A. Semashko National Research Institute of Public Health, Moscow, Russian Federation
Published: September 2021

Objective: To analyze marketing strategies and patient attraction instruments in medical organizations of the Russian medical services market. Methods: The analysis of marketing strategies and tools for attracting patients in medical organizations of the Russian medical services market was carried out on the basis of the study presented by EY during a three-step survey of the largest Russian private medical organizations operating in the commercial medicine market in the Russian healthcare system. Results: In the condition of growing competition in the medical service market, a significant factor in attracting and retaining patients is the high level of qualifications of doctors and medical personnel. Another factor is the doctor’s skill in finding contact with the patient, so far as consumers of medical service cannot always assess the quality of received medical aid and therefore very often form their impression of visiting a medical organization based on the communication and participation of the doctor. Conclusions: The analysis of the research results allowed to make conclusions about the development of online advertising on the Internet as an effective marketing instrument for medical service. Keywords: Marketing, healthcare, medical service market, marketing strategy, advertising.
OUR EXPERIENCE OF IMMUNOHISTOCHEMICAL ASSAY IN BREAST CANCER
Authors:   Department of Oncology, Institute of Postgraduate Education in Healthcare of the Republic of Tajikistan, Dushanbe, Republic of Tajikistan, RASULOV S.R. , VASIKHOV SH.A. ,   Department of Pathomorphology and Immunohistochemistry of Human Tumors, Republican Cancer Research Center, Dushanbe, Republic of Tajikistan
Published: September 2021

Objective: Analysis of the first experience of immunohistochemical (IHC) diagnostics of breast cancer (BC) in the Republic of Tajikistan for 2018- 2020. Methods: The results of the IHC study of tumor samples obtained by trephine biopsy in 142 patients and the surgical material after radical surgery in 110 patients have been studied. DAKO (Denmark) standard sets used for IHC assay. The staining carried out by manual methodology of the standard protocol provided by the company. The expression of ER and PR, HER2/neu and Ki-67 was determined. Receptive body expression of the ER and PR was evaluated by a point system, by the color intensity and the proportion of stained cells. The degree of HER2/neu expression was determined based on the staining of tumor cell membranes. To determine the threshold value of Ki-67 and subtypes of BC, we used the recommendations of the panel of experts of the St. Gallen Conference on Breast Cancer, proposed in 2013. Results: ER- and PR-positive tumors were found in 54.8% of patients. Negative expression of ER and PR was observed in 38.9% of cases. HER2/neu negative tumor status was found in 68.4%, HER2/neu positive – in 28.8% of cases. Low proliferative activity of Ki-67 was observed in 35.3% of patients, and high proliferative activity – in 64.7% of women. Three times negative BC was found in 23% of patients. Conclusions: High proliferation of steroid hormone receptors, the low proliferation of Ki-67 and absence of HER2/neu are considered favorable prognostic factors. Overexpression of HER2/neu is an unfavorable prognostic sign. High proliferation of Ki-67 is a direct indication for prescribing chemotherapeutic treatment. If technical capabilities are available, the IHC method should be developed in clinics where diagnostic and treatment of BC are conducted. Keywords: Breast cancer, immunohistochemical assay, hormone receptors, steroids, prediction.
OUR EXPERIENCE OF 4360 LAPAROSCOPIC CHOLECYSTECTOMY FOR CHOLELITHIASIS
Authors:   Department of Endoscopic Surgery, Republican Scientific Center for Cardiovascular Surgery, Dushanbe, Republic of Tajikistan, BOKIEV F.B. , RASHIDOV F.SH. ,   Department of Endoscopic Surgery, Republican Scientific Center for Cardiovascular Surgery, Dushanbe, Republic of Tajikistan, RAKHMONOV D.A. ,   Department of Surgical Diseases № 2 named after Academician N.U. Usmanov, Avicenna Tajik State Medical University, Dushanbe, Republic of Tajikistan, AMONOV SH.SH. ,   Department of Surgical Diseases № 2 named after Academician N.U. Usmanov, Avicenna Tajik State Medical University, Dushanbe, Republic of Tajikistan
Published: September 2021

Objective: Analysis of our own experience in performing laparoscopic cholecystectomy (LCE) for cholelithiasis (CHL). Methods: The study is based on the results of 4360 LCE in patients with cholelithiasis. Among the patients, women predominated – 3732 (85.6%), the average age of patients was 52.0±3.5 years. The structure of nosologies: chronic calculous cholecystitis – 3310 (75.9%), acute calculous cholecystitis – 1050 (24.1%). The operations were performed under general endotracheal anaesthesia with carbon dioxide insufflations; the location of the operating team was of the «American» type. Results: LCE was performed in 96.5% of patients, access conversion to open surgery was required in 3.5% of cases. The most common causes of conversion were the presence of a massive adhesive process (59.6%) and destructive changes in the walls of the gallbladder (9.93%). In the ICU, the operated patients were observed on average for 4±2.5 hours, the postoperative stay of patients in the hospital ward was 1.7±1.2 days. Immediate postoperative complications were noted in 1.63% of cases, mortality was 0.13%. Conclusions: Based on their own experience, the authors agree with the postulate that the LCE is the «gold standard» in gallbladder surgery in patients with gallstone disease. At the same time, purposeful preoperative preparation, careful selection of patients, high qualification of the surgeon, as well as adequate postoperative management of patients are the main factors in achieving good outcome. The complexity of surgical techniques can be reduced by collectively addressing complex situations of general somatic status by the active involvement of associated professionals. Keywords: Gallstone disease, laparoscopic cholecystectomy, conversion, early postoperative complications.
CARDIAC PARAGANGLIOMA FOUND DURING ANGINA EVALUATION
Authors:   Cardiac Catheterization Laboratories, Leon H. Charney Division of Cardiology, Department of Medicine, New York University Grossman School of Medicine, New York, USA, QAMAR A. , VAYNBLAT M. ,   Division of Cardiothoracic Surgery, New York University Grossman School of Medicine, New York, USA, KOECKERT M. ,   Division of Cardiothoracic Surgery, New York University Grossman School of Medicine, New York, USA, ZHOU F. ,   Department of Pathology, New York University Grossman School of Medicine, New York, USA, BABAEV A. ,   Cardiac Catheterization Laboratories, Leon H. Charney Division of Cardiology, Department of Medicine, New York University Grossman School of Medicine, New York, USA
Published: September 2021

Cardiac paragangliomas are an extremely rare cause of cardiac masses. We present a case of a cardiac paraganglioma presenting as a highly vascular mass on coronary angiography in a patient with angina, we discuss the challenges in its diagnostic evaluation and management. Keywords: Paraganglioma, heart, tumor, diagnosis.
ANALISIS SWOT PELAYANAN KESEHATAN RUMAH SAKIT UMUM LIRBOYO KOTA KEDIRI TAHUN 2019
Authors: Nugraheni Reny , Kirana Gerardin Ranind
Published: September 2021

Analisis SWOT merupakan evaluasi terhadap lingkungan internal (Kekuatan/Strength, dan Kelemahan/Weakness) dan lingkungan eksternal (Peluang/Opportunity, dan Tantangan/Threats) (Grewal & Levy, 2008). Merujuk pada pelayanan kesehatan Rumah Sakit Umum Lirboyo Kota Kediri maka dilakukan analisis SWOT untuk membuat suatu strategi yang dapat memberikan gambaran mengenai lingkungan internal dan eksternal secara lebih komprehensif dan dapat dijadikan untuk pengambilan keputusan. Metode penelitian ini menggunakan studi literatur yang berasal dari makalah sebagai bahan acuan pembuatan jurnal menggunakan pendekatan Faktor Strategi Internal (IFAS) serta Faktor Strategi Eksternal (EFAS). Hasilnya pada perhitungan matriks diketahui bahwa kondisi Rumah Sakit Umum Lirboyo terletak di kuadran I artinya strategi pertumbuhan cepat/agresif. Situasi ini menguntungkan bagi rumah sakit karena memiliki peluang dan kekuatan yang baik sehingga dapat mengarahkan seluruh potensi internal organisasi untuk memanfaatkan peluang yang ada dengan dioptimalkan dan meminimalisir kelemahan dan ancaman. Dengan dilakukan analisis SWOT ini diharapkan perusahaan/organisasi khususnya Rumah Sakit Umum Lirboyo Kota Kediri mampu untuk memaksimalkan adanya kekuatan dan peluang yang ada dan meminimalkan kelemahan dan tantangan sehingga dapat membuat rancangan strategi guna kemajuan rumah sakit tersebut.
TERAPI AKUPRESUR MENURUNKAN TEKANAN DARAH PASIEN HIPERTENSI
Authors: Sukmadi Arfiyan , Alifariki La Ode , Arfini Kasman A Ida Mardhiah , Siagian Heriviyatno J
Published: September 2021

Masih tingginya prevalensi penyakit hipertensi, maka pasien hipertensi perlu mendapatkan penanganan yang aman dari efek samping mengobatan, karena pengobatan harus dilakukan dalam jangka waktu panjang. Dalam penelitian ini, peneliti menggunakan terapi akupresur untuk menurunkan tekanan darah pasien hipertensi. Penelitian ini menggunakan quasi eksperiment dengan one group pre dan post test design. Sampel dalam penelitian ini melibatkan pasien hipertensi sebanyak 15 orang. Hasil penelitian ini menunjukkan bahwa setelah diberi terapi akupresur, tekanan darah sistolik menurun senanyak 15 orang dan tekanan diastolic menurun sebanyak 12 orang dan meningkat sebanyak 3 orang. Sebelum diberi terapi mean tekanan darah sistolik adalah 164,02mmHg dan setelah terapi akupresur menurun menjadi 141,44mmHg, dan mean tekanan diastolic sebelum terapi sebesar 91,49 mmHg dan menurun setelah terapi menjadi 86,71mmHg. Hasil uji paired t test menunjukkan bahwa tekanan darah distolik (p value =0,000) dan tekanan darah diastolic (p value = 0,000), artinya bahwa ada pengaruh terapi akupresur pada penurunan tekanan darah. Terapi akupresur efektif dalam menurunkan tekanan darah, sehingga sangat diharapkan bahwa terapi modalitas ini dapat diimplementasikan pula di fasilitas pelayanan kesehatan pemerintah oleh petugas kesehatan khususnya perawat dalam rangka mengurangi efek samping pengobatan medis
Genetic status of Centella asiatica (L.) Urb. (Indian pennywort): A review
Authors: Mathavaraj Sakthipriya , Sabu Kalluvettankuzhy Krishnannair
Published: September 2021

In recent years, demand for medicinal plants increased due to the rise in attraction towards herbal products which are safer compared to modern drugs. Centella asiatica (L.) Urb is known as an important medicinal plant in herbal medicinal systems. It also used as an active ingredient for many products in the pharmaceutical and cosmetic industry. So far, review on this plant concerns mainly on medicinal, cosmetology and photochemical works reported. This review presents the genetic studies conducted in this herb along with a mention on conservation. Since documenting and studying genetic variation and its composition has an important connection for the understanding of evolution and improving the conservation of this species.
Development of a CubeSat Single Channel LoRa Receiver Module for Space-based IoT Application
Authors: Ivansyah Muhammad Dzaky , Edwar Edwar , Adriansyah Nachwan Mufti , Ryanu Harfan Hian , Setiawan Dhoni Putra
Published: September 2021

CubeSat attracts many researchers due to its low production and deployment cost. One of the application is implemented in low data rate communication or machine to machine (M2M) with IoT devices in remote areas such as islands, forests, and mountains. In this study, a CubeSat receiver for IoT communication in remote areas has been developed and realized. A LoRa SX1276 chip is used for processing passband signals captured by the antenna. The device has a amplifier gain of 20.92 dB, 390 mW power consumption, and operating frequency of 923 MHz. The developed CubeSat is expected to provide a low bit rate of 5468.750 bps for SF 7 and 292.969 for SF 12 , the receiver serves as a concentrator for monitoring devices in rural areas.
Uso de imunobiológicos no manejo da asma grave em pediatria
Authors: Silva Marina Teixeira de Oliveira , Naves Giovanna Bezerra , Silva Beatriz Vieira Nascimento , Vasconcelos Juliana Azevedo de , Castro Luíza Araújo , Carvalho Lethicya Alves Sousa , Cruz Danielle Sampaio Lima da
Published: September 2021

Objetivo: Revisar os principais imunobiológicos utilizados para o tratamento da asma grave na população pediátrica. Revisão bibliográfica:  A asma grave ainda prevalece como grande causa de morbidade na infância. A utilização de imunomoduladores tem obtido grandes resultados positivos, especialmente o Omalizumabe, medicamento que possui maior número de pesquisas e benefícios comprovados.  Desde que o Omalizumabe foi aprovado para o manejo da asma, diferentes terapias biológicas revolucionaram a abordagem terapêutica de doenças alérgicas graves não controladas em crianças. Fármacos como Mepolizumabe, Reslizumabe, Benralizumabe e Dupilumabe ainda estão em contínuos testes clínicos e futuramente podem ser terapêuticos para populações pediátricas específicas e a solucionar as principais incertezas que os imunobiológicos apresentam acrescentados nos protocolos. Considerações finais: Torna-se evidente, portanto, que os imunobiológicos representam uma alternativa promissora para o tratamento da asma severa pois objetivam tratar especificamente as vias inflamatórias da asma. No entanto, estudos comparativos são necessários para ajudar os médicos a escolher a melhor opção.
Compreensão de médicos residentes, cirurgiões e anestesiologistas sobre o protocolo de cirurgia segura em um hospital de ensino
Authors: Lara Taynah Ivanir da Costa de , Tonini Nelsi Salete , Maraschin Maristela Salete , Silva Débora Cristina Ignácio da , Borges Fabieli , Lopes Danieli
Published: September 2021

Objetivo: Identificar a percepção de médicos residentes, cirurgiões e anestesiologistas de um hospital público de ensino, acerca da Lista de Verificação de Cirurgia Segura (LVCS). Métodos: Estudo descritivo-exploratório, qualitativo, comanálise do Discurso do Sujeito Coletivo (DSC) em um hospital escola, com14sujeitos atuantes no ano de 2020 no Centro Cirúrgico, utilizando entrevista semiestruturada com cinco questões do tema. Resultados: Foram construídos 10 (dez) DSC e 13 ideias centrais, sendo: ausência de treinamento; desconhecimento do protocolo e treinamento nas residências médicas, cumprimento frágil do protocolo, diminuição dos riscos, viável/necessário, alta rotatividade de pessoal, compromisso da gestão e equipe multiprofissional, divulgação e comprometimento, orientação e cobrança, checklist digital, alteração do padrão de cores do papel impresso, realizar o checklist verbalmente e responsabilidade do profissional com o paciente. Conclusão: Necessário promover ações educativas de treinamento e aperfeiçoamento profissional, auditorias in loco, para construção dos indicadores do hospital e retorno aos profissionais.
Detecção precoce do câncer de pele na atenção básica
Authors: Carminate Camila Baquieti , Rocha Ágatha Barbosa , Gomes Bárbara Poggiali , Nakagawa Frederico Noboro Figueiredo , Oliveira Gustavo Lopes de , Vieira Júlia Fraga , Almeida Larissa Mariani Rezende , Ferreira Luísa Dias Toledo , Andrade Pedro Duarte Moreira , Silva Rafaela Almeida
Published: September 2021

Objetivo: Analisar o papel da Atenção Básica na detecção precoce do câncer de pele, visando mostrar as principais estratégias utilizadas. Revisão bibliográfica: O câncer de pele é a neoplasia que possui maior incidência no Brasil. A identificação do câncer em fase inicial, precoce, ou ainda de lesões pré-malignas, tais como queratoses actínicas e nevos melanocíticos displásicos, é um fator de bom prognostico devido ao tratamento precoce, com maiores chances de cura e menores sequelas cirúrgicas. Devido ao fato de a pele ser um órgão de fácil visualização, é importante orientar a população em relação aos sinais de alerta. Os médicos de família devem fazer o rastreio baseado no exame clínico visual da pele, incluindo a regra do ABCDE (assimetria da lesão, bordas irregulares, heterogeneidade de cor; diâmetro mais de 6mm e evolução ao longo do tempo), pode-se realizar também exames auxiliares, como a dermatoscopia, exame confocal e mapeamento das lesões estudos feitos pelo dermatologista. Considerações finais: É importante orientar o paciente em reação da realização do autoexame, pelo menos uma vez no mês, para estar sempre atento às possíveis alterações.