bluuebunny/crossref_metadata_2025 huggingface dataset:
A 3‐Fluoro‐4‐hexylthiophene‐Based Wide Bandgap Donor Polymer for 10.9% Efficiency Eco‐Friendly Nonfullerene Organic Solar Cells
Authors: Yu Jeong Eun , Jeon Sung Jae , Choi Jun Young , Han Yong Woon , Ko Eui Jin , Moon Doo Kyung
Published: January 2019

Nonfullerene organic solar cells (NFOSCs) are attracting increasing academic and industrial interest due to their potential uses for flexible and lightweight products using low‐cost roll‐to‐roll technology. In this work, two wide bandgap (WBG) polymers, namely P(fTh‐BDT)‐C6 and P(fTh‐2DBDT)‐C6, are designed and synthesized using benzodithiophene (BDT) derivatives. Good oxidation stability and high solubility are achieved by simultaneously introducing fluorine and alkyl chains to a single thiophene (Th) unit. Solid P(fTh‐2DBDT)‐C6 films present WBG optical absorption, suitable frontier orbital levels, and strong π–π stacking effects. In addition, P(fTh‐2DBDT)‐C6 exhibits good solubility in both halogenated and nonhalogenated solvents, suggesting its suitability as donor polymer for NFOSCs. The P(fTh‐2DBDT)‐C6:3,9‐bis(2‐methylene‐(3‐(1,1‐dicyanomethylene)‐indanone))‐5,5,11,11‐tetrakis(5‐hexylthienyl)‐dithieno[2,3‐d:2′,3′‐d′]‐s‐indaceno[1,2‐b:5,6‐b′]dithiophene (ITIC‐Th) based device processed using chlorobenzene/1,8‐diiodooctane (CB/DIO) exhibits a remarkably high power conversion efficiency (PCE) of 11.1%. Moreover, P(fTh‐2DBDT)‐C6:ITIC‐Th reaches a high PCE of 10.9% when processed using eco‐friendly solvents, such as o‐xylene/diphenyl ether (DPE). The cell processed using CB/DIO maintains 100% efficiency after 1272 h, while that processed using o‐xylene/DPE presents a 101% increase in efficiency after 768 h and excellent long‐term stability. The results of this study demonstrate that simultaneous fluorination and alkylation are effective methods for designing donor polymers appropriate for high‐performance NFOSCs.
Thermopower Modulation Clarification of the Operating Mechanism in Wide Bandgap BaSnO3–SrSnO3 Solid‐Solution Based Thin Film Transistors
Authors: Sanchela Anup V. , Wei Mian , Cho Hai Jun , Ohta Hiromichi
Published: January 2019

The transparent oxide semiconductor (TOS) with large bandgap (Eg ≈ 4 eV) based thin‐film transistors (TFTs) showing both high carrier mobility and UV–visible transparency has attracted increasing attention as a promising component for next generation optoelectronics. Among TOSs, BaSnO3–SrSnO3 solid‐solutions (Eg = 3.5–4.2 eV) are good candidates because the single crystal shows very high mobility. However, the TFT performance has not been optimized due to the lack of fundamental knowledge especially the effective thickness (teff) and the carrier effective mass (m*). Here, it is demonstrated that the electric field thermopower (S) modulation method addresses this problem by combining with the standard volume carrier concentration (n3D) dependence of S measurements. By comparing the electric field accumulated sheet carrier concentration (n2D) and n3D at same S, it is clarified that the teff (n2D/n3D) of the conducting channel becomes thicker with increasing Sr concentration, whereas the m* becomes lighter. The former would be due to the increase of Eg and latter would be due to the enhancement of overlap population of neighboring Sn 5s orbitals. The present analyses technique is useful to experimentally clarify the teff and m*, and essentially important to realize advanced TOS‐based TFTs showing both high optical transparency and high mobility.
Peyronie's disease: intralesional collagenase injections
Authors: Bardoli Antonio D , Abedin Asad , Modgil Vaibhav , Ralph David J
Published: January 2019

While surgery is currently the standard treatment for Peyronie's disease it is not without adverse effects, including erectile dysfunction. In this article the authors review the evidence for intralesional injections of collagenase clostridium histolyticum.
Crude oil analysis by X‐ray scattering technique
Authors: Oliveira Davi F. , Silva Ana Cecília , Figueiredo Willians P. , Anjos Marcelino J. , Lopes Ricardo T.
Published: January 2019

Composed of hydrocarbons and other substances, petroleum is classified as a nonrenewable source of energy. In its unrefined form, it is called crude oil. Currently, its derivates are widely used in domestic and industrial environments, with the greatest exponent being motor fuels and lubricating oils. Due to the overwhelming demand, new oil wells in the presalt region of Brazil are going to be drilled, which will, in its turn, increase the demand for analysis and require the use of less costly technologies. The purpose of this paper is to present an experimental method that aims at characterizing crude oil samples through their X‐ray scattering profiles without the need for any chemical preparation to be performed in advance, which will enable this method to be used for analyzing samples immediately after their extraction. For the experiment, a portable X‐ray scattering system composed by an X‐ray tube (silver anode) and a Si‐PIN detector was used in order to analyze samples from different wells. The process consisted in establishing a linear relationship between the effective atomic number and the ratio between peak intensities of Compton and Rayleigh scattering from known samples. The linear function, verified experimentally, was then applied to samples of crude oil, and the results showed that it is possible to characterize them on the basis of the Rayleigh to Compton scattering ratio. After the analysis, a multiple comparison test performed on the samples proved that this methodology indeed allows to differentiate samples of different origins and to verify the compatibility of samples extracted from the same well.
Crises and Responses: Government Policies and the Machine-Building Cartels in Hungary, 1919–1949
Authors: HIDVÉGI MÁRIA
Published: January 2019

What impact have government policies had on the private sector’s response to economic crises, in particular on its decisions for restructuring and adaptation? The Hungarian machine-building industry from 1919 to 1949 provides an interesting case study for these interrelations between business and politics. The study focuses on the role of cartels in organizing responses to crises. The case study is based on a survey of the cartel agreements and investigates why cartels provided solutions only to short-term crises, if they provided solutions at all. The hypothesis is that government policies played a substantial part in the story, as they did not provide enough incentives for coordinated responses to structural change. The years 1919 to 1949 encompass the crises caused by the territorial and political change in East Central Europe after World War I, the Great Depression, and World War II and its aftermath. Depicting the responses of the machine-building industry through the experience of one of its key companies and its cartels—Ganz & Co.—this article analyzes the influence of the institutional framework on short- and long-term adaptation to crises.
Coherent structures in the linearized impulse response of turbulent channel flow
Authors: Vadarevu Sabarish B. , Symon Sean , Illingworth Simon J. , Marusic Ivan
Published: January 2019

We study the evolution of velocity fluctuations due to an isolated spatio-temporal impulse using the linearized Navier–Stokes equations. The impulse is introduced as an external body force in incompressible channel flow at $Re_{\unicode[STIX]{x1D70F}}=10\,000$. Velocity fluctuations are defined about the turbulent mean velocity profile. A turbulent eddy viscosity is added to the equations to fix the mean velocity as an exact solution, which also serves to model the dissipative effects of the background turbulence on large-scale fluctuations. An impulsive body force produces flow fields that evolve into coherent structures containing long streamwise velocity streaks that are flanked by quasi-streamwise vortices; some of these impulses produce hairpin vortices. As these vortex–streak structures evolve, they grow in size to be nominally self-similar geometrically with an aspect ratio (streamwise to wall-normal) of approximately 10, while their kinetic energy density decays monotonically. The topology of the vortex–streak structures is not sensitive to the location of the impulse, but is dependent on the direction of the impulsive body force. All of these vortex–streak structures are attached to the wall, and their Reynolds stresses collapse when scaled by distance from the wall, consistent with Townsend’s attached-eddy hypothesis.
ON THE INTERPLAY BETWEEN EFFECTIVE NOTIONS OF RANDOMNESS AND GENERICITY
Authors: BIENVENU LAURENT , PORTER CHRISTOPHER P.
Published: January 2019

In this paper, we study the power and limitations of computing effectively generic sequences using effectively random oracles. Previously, it was known that every 2-random sequence computes a 1-generic sequence (as shown by Kautz) and every 2-random sequence forms a minimal pair in the Turing degrees with every 2-generic sequence (as shown by Nies, Stephan, and Terwijn). We strengthen these results by showing that every Demuth random sequence computes a 1-generic sequence and that every Demuth random sequence forms a minimal pair with every pb-generic sequence (where pb-genericity is an effective notion of genericity that is strictly between 1-genericity and 2-genericity). Moreover, we prove that for every comeager${\cal G} \subseteq {2^\omega }$, there is some weakly 2-random sequenceXthat computes some$Y \in {\cal G}$, a result that allows us to provide a fairly complete classification as to how various notions of effective randomness interact in the Turing degrees with various notions of effective genericity.
The number of solutions of the Erdős-Straus Equation and sums ofkunit fractions
Authors: Elsholtz Christian , Planitzer Stefan
Published: January 2019

We prove new upper bounds for the number of representations of an arbitrary rational number as a sum of three unit fractions. In particular, for fixedmthere are at most${\cal O}_{\epsilon }(n^{{3}/{5}+\epsilon })$solutions of${m}/{n} = {1}/{a_1} + {1}/{a_2} + {1}/{a_3}$. This improves upon a result of Browning and Elsholtz (2011) and extends a result of Elsholtz and Tao (2013) who proved this whenm=4 andnis a prime. Moreover, there exists an algorithm finding all solutions in expected running time${\cal O}_{\epsilon }(n^{\epsilon }({n^3}/{m^2})^{{1}/{5}})$, for any$\epsilon \gt 0$. We also improve a bound on the maximum number of representations of a rational number as a sum ofkunit fractions. Furthermore, we also improve lower bounds. In particular, we prove that for given$m \in {\open N}$in every reduced residue classemodfthere exist infinitely many primespsuch that the number of solutions of the equation${m}/{p} = {1}/{a_1} + {1}/{a_2} + {1}/{a_3}$is$\gg _{f,m} \exp (({5\log 2}/({12\,{\rm lcm} (m,f)}) + o_{f,m}(1)) {\log p}/{\log \log p})$. Previously, the best known lower bound of this type was of order$(\log p)^{0.549}$.
Decay rates at infinity for solutions to periodic Schrödinger equations
Authors: Elton Daniel M.
Published: January 2019

We consider the equation Δu = Vu in the half-space ${\open R}_ + ^d $, d ⩾ 2 where V has certain periodicity properties. In particular, we show that such equations cannot have non-trivial superexponentially decaying solutions. As an application this leads to a new proof for the absolute continuity of the spectrum of particular periodic Schrödinger operators. The equation Δu = Vu is studied as part of a broader class of elliptic evolution equations.
Some congruences involving fourth powers of central q-binomial coefficients
Authors: Guo Victor J. W. , Wang Su-Dan
Published: January 2019

We prove some congruences on sums involving fourth powers of central q-binomial coefficients. As a conclusion, we confirm the following supercongruence observed by Long [Pacific J. Math. 249 (2011), 405–418]:
$$\sum\limits_{k = 0}^{((p^r-1)/(2))} {\displaystyle{{4k + 1} \over {{256}^k}}} \left( \matrix{2k \cr k} \right)^4\equiv p^r\quad \left( {\bmod p^{r + 3}} \right),$$where p⩾5 is a prime and r is a positive integer. Our method is similar to but a little different from the WZ method used by Zudilin to prove Ramanujan-type supercongruences.
LINEAR QUOTIENTS AND MULTIGRADED SHIFTS OF BOREL IDEALS
Authors: BAYATI SHAMILA , JAHANI IMAN , TAGHIPOUR NADIYA
Published: January 2019

We investigate whether the property of having linear quotients is inherited by ideals generated by multigraded shifts of a Borel ideal and a squarefree Borel ideal. We show that the ideal generated by the first multigraded shifts of a Borel ideal has linear quotients, as do the ideal generated by the $k$th multigraded shifts of a principal Borel ideal and an equigenerated squarefree Borel ideal for each $k$. Furthermore, we show that equigenerated squarefree Borel ideals share the property of being squarefree Borel with the ideals generated by multigraded shifts.
INTEGER POLYGONS OF GIVEN PERIMETER
Authors: EAST JAMES , NILES RON
Published: January 2019

A classical result of Honsberger states that the number of incongruent triangles with integer sides and perimeter$n$is the nearest integer to$n^{2}/48$($n$ even) or$(n+3)^{2}/48$($n$ odd). We solve the analogous problem for$m$-gons (for arbitrary but fixed$m\geq 3$) and for polygons (with arbitrary number of sides).
A Note on the Fundamental Group of Kodaira Fibrations
Authors: Vidussi Stefano
Published: January 2019

The fundamental group π of a Kodaira fibration is, by definition, the extension of a surface group $\Pi_b$ by another surface group $\Pi _g$, i.e.
$$1 \rightarrow \Pi_g \rightarrow \pi \rightarrow \Pi_b \rightarrow 1.$$
Conversely, Catanese (2017) inquires about what conditions need to be satisfied by a group of that sort in order to be the fundamental group of a Kodaira fibration. In this short note we collect some restrictions on the image of the classifying map $m \colon \Pi_b \to \Gamma_g$ in terms of the coinvariant homology of $\Pi_g$. In particular, we observe that if π is the fundamental group of a Kodaira fibration with relative irregularity g−s, then $g \leq 1+ 6s$, and we show that this effectively constrains the possible choices for π, namely that there are group extensions as above that fail to satisfy this bound, hence it cannot be the fundamental group of a Kodaira fibration. A noteworthy consequence of this construction is that it provides examples of symplectic 4-manifolds that fail to admit a Kähler structure for reasons that eschew the usual obstructions.
RUMOR AND HISTORY REVISITED: ‘MUMIANI’ IN COASTAL KENYA, 1945
Authors: DINGLEY ZEBULON
Published: January 2019

This article analyzes an instance of collective panic about gangs of killers calledWatu wa Mumiani(‘MumianiPeople’) in Digo District, Kenya in 1945. Popularly believed to work for the colonial government,Watu wa Mumianiwere said to abduct Africans from roads and kill them for their blood. I offer an interpretation of this episode in terms of the history of a medicine calledMumia, a nineteenth-century ritual calledMung'aro, regional strategies for surviving famine (including ‘pawning’ kin), and a wartime labor conscription campaign. Rather than emphasize the alterity of ‘vampires’ likeWatu wa Mumiani, I show how the 1945 panic articulates concerns about powerful intermediaries, arguing that the stories told about them encode a history of concerns about predatory patrons, especially under conditions of ecological distress.
REINVENTINGIMBALUAND FORCIBLE CIRCUMCISION: GISU POLITICAL IDENTITY AND THE FIGHT FOR MBALE IN LATE COLONIAL UGANDA
Authors: KHANAKWA PAMELA
Published: January 2019

Ugandan colonial authorities carved Bugisu and Bukedi districts out of Mbale district in 1954, isolating Mbale town as a separate entity. With ethnic tensions escalating as independence approached, Gisu and Gwere fought for Mbale's ownership. Empowered by decentralisation, Bugisu District Council pressed the colonial state to declare Mbale part of Bugisu, viewing the town as key to the region's wealth, and providing a symbolic status similar to that enjoyed by Uganda's leading ethnic groups. Gisu activists reinvented tradition as a tool of political advocacy, exerting hyper-masculine power over Mbale's non-circumcising Gwere residents through forcible circumcision. Gisu reformulation of a cultural practice within an urban struggle challenges previous categorisations of the Mbale case as merely another local obstacle to Uganda's peaceful decolonisation. Evidence analysed in this article contributes to a new understanding of East Africa's uneasy transition to self-government, and to the role of ethnic competition within late-colonial mobilisations more broadly.
Petitions and Local Politics in the Late Mughal Empire: The view from Kol, 1741
Authors: KAICKER ABHISHEK
Published: January 2019

This article uses a 1741 testimonial document from Kol (present-day Aligarh) to explore the workings of petitions in the local politics of the late Mughal empire. I suggest that even solitary documents such as this can be read as artefacts of the continuing processes of local politics which operated in excess of the administrative logic of the Mughal state. After surveying the place of petitions in the Mughal apparatus of justice from an administrative perspective, I examine the story of a vanished artisan named Hira to demonstrate that even scattered documents from the Mughal archive can reveal traces of the larger political processes of which a petition might be a single example. In this light, I demonstrate how the testimonial at hand can illuminate the everyday workings of the social and political order of the locality, and its relationship with larger structures of ideology and state power in an era of political decentralization.
In the Presence of Witnesses: Petitioning and judicial ‘publics’ in western India,circa1600–1820
Authors: O'HANLON ROSALIND
Published: January 2019

British observers of the nineteenth-century panchayat were convinced that it represented a judicial forum of great antiquity, in which petitioners were able to gain local and direct access to justice. They contrasted the panchayat favourably with the delays and frustrations that beset the eighteenth-century East India Company's attempts to channel all petitions through its own courts. This article examines the history of the pre-colonial panchayat in western India and its early modern predecessors. During the early modern centuries, a diverse array of state-level and local corporate bodies made up the landscape for the submission of petitions and the hearing of suits. Although many suits were local in nature, the process of hearing and adjudication itself gave these judicial spaces a significant ‘public’ dimension, and their forms of argumentation frequently invoked general principles of justice and moral order. From the early eighteenth century, the new form of the panchayat came to supersede these older corporate bodies and to reshape the forms of public that gathered around them. The Maratha state, based in Pune, sought firmer control over revenue and justice. State officials promoted the panchayat as a new type of judicial arena, weakening the local corporate institutions and tying them more closely to the Pune court.
Petitions, the City, and the Early Colonial State in South India
Authors: BALACHANDRAN APARNA
Published: January 2019

This article explores the entwined history of early colonial urbanism and the articulation of legal subjectivity under East India Company rule in South India. More specifically, it looks at petitions from outcaste labouring groups to the Madras government in the late eighteenth and early nineteenth centuries. Although early colonial petitions were unequivocally products of colonial rule, which derived their distinctive form and language from colonial law, a reading of the petition archive is one of the only ways to achieve a historical understanding of the city of Madras as it was experienced by its less privileged inhabitants. This article looks at the delineation of the communal selfhood of subaltern urban communities through petition narratives, arguing that the variety and innovativeness displayed by petition writers is testament both to the acceptance of colonial legality and to the agency of native subjects in negotiating with, and appropriating the language and rationale of, the colonial legal regime.
A Petition to Kill: Efficacious arzees against big cats in India
Authors: MATHUR NAYANIKA
Published: January 2019

In a political culture that experiences inordinately high levels of petitioning, what makes for a successful petition? This article studies petitions that have been efficacious in their appeals to capture or kill big cats in Himalayan India. The rates of success for any appeal against big cats are low in contemporary India, given the stringent legal regime that is geared almost exclusively towards the protection of the charismatic and endangered big cats as well as the hegemonic position occupied by wildlife conservationism. Furthermore, not only is it difficult to petition against cossetted big cats, but it is also not an easy task for any petition to be heard and acquiesced to. Through an ethnography of efficacious petitions, this article makes three related interventions. First, and in the process of attending to the rarity of a handful of efficacious petitions, this article argues for expanding our conceptualization of what, in practice, a petition is. It does so by outlining the changing forms of efficacious petitions, which can range from a telephone call, a register entry, a WhatsApp message from a smart phone, to the more ‘traditional’ paper-based petition. Beyond its ever-evolving medium, this article demonstrates the criticality of folding petitioning into a wider process that involves planning, performance, perseverance, repetition, and the capacity to elicit visceral responses. Finally, through an ethnographic foregrounding of human-big cat interactions, it demonstrates how an acceptance and elaboration of animal agency enriches the study of politico-legal processes.
The effect of rehabilitation combined with cognitive remediation on functioning in persons with severe mental illness: systematic review and meta-analysis
Authors: van Duin Daniëlle , de Winter Lars , Oud Matthijs , Kroon Hans , Veling Wim , van Weeghel Jaap
Published: January 2019

Background

Psychiatric rehabilitation (PR) can improve functioning in people with severe mental illness (SMI), but outcomes are still suboptimal. Cognitive impairments have severe implications for functioning and might reduce the effects of PR. It has been demonstrated that performance in cognitive tests can be improved by cognitive remediation (CR). However, there is no consistent evidence that CR as a stand-alone intervention leads to improvements in real-life functioning. The present study investigated whether a combination of PR and CR enhances the effect of a stand-alone PR or CR intervention on separate domains of functioning.

Method

A meta-analysis of randomized controlled trials of PR combined with CR in people with SMI was conducted, reporting on functioning outcomes. A multivariate meta-regression analysis was carried out to evaluate moderator effects.

Results

The meta-analysis included 23 studies with 1819 patients. Enhancing PR with CR had significant beneficial effects on vocational outcomes (e.g. employment rate: SMD = 0.41), and social skills (SMD = 0.24). No significant effects were found on relationships and outcomes of community functioning. Effects on vocational outcomes were moderated by years of education, intensity of the intervention, type of CR approach and integration of treatment goals for PR and CR. Type of PR was no significant moderator.

Conclusions

Augmenting PR by adding cognitive training can improve vocational and social functioning in patients with SMI more than a stand-alone PR intervention. First indications exist that a synergetic mechanism also works the other way around, with beneficial effects of the combined intervention compared with a stand-alone CR intervention.
Low-Cost Receiver and Network Real-Time Kinematic Positioning for use in Connected and Autonomous Vehicles
Authors: Ning Fang-Shii , Meng Xiaolin , Wang Yi-Ting
Published: January 2019

Connected and Autonomous Vehicles (CAVs) have been researched extensively for solving traffic issues and for realising the concept of an intelligent transport system. A well-developed positioning system is critical for CAVs to achieve these aims. The system should provide high accuracy, mobility, continuity, flexibility and scalability. However, high-performance equipment is too expensive for the commercial use of CAVs; therefore, the use of a low-cost Global Navigation Satellite System (GNSS) receiver to achieve real-time, high-accuracy and ubiquitous positioning performance will be a future trend. This research used RTKLIB software to develop a low-cost GNSS receiver positioning system and assessed the developed positioning system according to the requirements of CAV applications. Kinematic tests were conducted to evaluate the positioning performance of the low-cost receiver in a CAV driving environment based on the accuracy requirements of CAVs. The results showed that the low-cost receiver satisfied the “Where in Lane” accuracy level (0·5 m) and achieved a similar positioning performance in rural, interurban, urban and motorway areas.
Genetic characterisation of Measles virus variants identified during a large epidemic in Milan, Italy, March–December 2017
Authors: Bianchi S. , Frati E.R. , Lai A. , Colzani D. , Ciceri G. , Baggieri M. , Lamberti A. , Senatore S. , Faccini M. , Mazzilli F. , Gramegna M. , Zehender G. , Magurano F. , Tanzi E. , Amendola A.
Published: January 2019

In 2017, Italy experienced a large measles epidemic with 5408 cases and four deaths. As Subnational Reference Laboratory of the Measles and Rubella surveillance NETwork (MoRoNET), the EpiSoMI (Epidemiology and Molecular Surveillance of Infections) Laboratory (University of Milan) set up rapid and active surveillance for the complete characterisation of the Measles virus (Mv) responsible for the large measles outbreak in Milan and surrounding areas (Lombardy, Northern Italy). The aims of this study were to describe the genetic profile of circulating viruses and to track the pathway of measles transmission. Molecular analysis was performed by sequencing the highly variable 450 nucleotides region of the N gene (N-450) of Mv genome. Two-hundred and ninety-nine strains of Mv were analysed. The phylogenetic analysis showed five different variants, two not previously described in the studied area, belonging to D8 and B3 genotypes. Three events of continuous transmission of autochthonous variants (D8-Osaka, D8-London and B3-Milan variants) and two events of continuous transmission of imported variants (B3-Dublin and D8-Hulu Langat) tracked five different transmission pathways. These pathways outlined two epidemic peaks: the first in April and the second in July 2017. The correlation between Mv variant and the epidemiological data may enable us to identify the sources of virus importation and recognise long-lasting virus transmission pathways.
Prevalence and risk factors of anaemia in hospitalised HIV-infected patients in southeast China: a retrospective study
Authors: Lai J. L. , Chen Y. H. , Liu Y. M. , Yuan J. J. , Lin J. , Huang A. Q. , Ye H. H.
Published: January 2019

The association between opportunistic infection (OI) and anaemia among HIV-infected patients remains to be studied. We investigated the prevalence and risk factors of anaemia in hospitalised HIV-infected patients to reveal the association between OI and anaemia. We conducted a retrospective study of HIV-positive hospitalised patients from June 2016 to December 2017 in Mengchao Hepatobiliary Hospital of Fujian Medical University. Patients’ information on socio-demographic and clinical characteristics were carefully collected. The comparison of anaemia prevalence between groups was conducted withχ2test. A logistic regression model was carried out to analyse the predictors of anaemia. The total prevalence of anaemia in hospitalised HIV-infected patients was 55.15%. The prevalence of mild, moderate and severe anaemia was 41.42%, 11.08% and 2.64%, respectively. Predictors independently associated with anaemia were: CD4 counts <50 cells/μl (odds ratio (OR): 6.376, 95% confidence interval (CI) = 1.916–21.215,P= 0.003), CD4 counts 50–199 cells/μl (OR: 6.303, 95% CI = 1.874–21.203,P= 0.003), co-infection with tuberculosis (TB) (OR: 2.703, 95% CI = 1.349–5.414,P= 0.005) or Penicillium marneffei (PM) (OR: 7.162, 95% CI = 3.147–15.299,P< 0.001). In Fujian, China, more than half inpatients with HIV were anaemic, but severe anaemia is infrequent. Lower CD4 counts, co-infection with TB or PM were independent risk factors for anaemia. Chinese HIV patients especially with TB, PM infection and low CD4 level should be routinely detected for anaemia to improve therapy.
CHARACTERIZATIONS OF BMO AND LIPSCHITZ SPACES IN TERMS OF WEIGHTS AND THEIR APPLICATIONS
Authors: WANG DINGHUAI , ZHOU JIANG , TENG ZHIDONG
Published: January 2019

Let $0<\unicode[STIX]{x1D6FC}<n,1\leq p<q<\infty$ with $1/p-1/q=\unicode[STIX]{x1D6FC}/n$, $\unicode[STIX]{x1D714}\in A_{p,q}$, $\unicode[STIX]{x1D708}\in A_{\infty }$ and let $f$ be a locally integrable function. In this paper, it is proved that $f$ is in bounded mean oscillation $\mathit{BMO}$ space if and only if $$\begin{eqnarray}\sup _{B}\frac{|B|^{\unicode[STIX]{x1D6FC}/n}}{\unicode[STIX]{x1D714}^{p}(B)^{1/p}}\bigg(\int _{B}|f(x)-f_{\unicode[STIX]{x1D708},B}|^{q}\unicode[STIX]{x1D714}(x)^{q}\,dx\bigg)^{1/q}<\infty ,\end{eqnarray}$$ where $\unicode[STIX]{x1D714}^{p}(B)=\int _{B}\unicode[STIX]{x1D714}(x)^{p}\,dx$ and $f_{\unicode[STIX]{x1D708},B}=(1/\unicode[STIX]{x1D708}(B))\int _{B}f(y)\unicode[STIX]{x1D708}(y)\,dy$. We also show that $f$ belongs to Lipschitz space $Lip_{\unicode[STIX]{x1D6FC}}$ if and only if $$\begin{eqnarray}\sup _{B}\frac{1}{\unicode[STIX]{x1D714}^{p}(B)^{1/p}}\bigg(\int _{B}|f(x)-f_{\unicode[STIX]{x1D708},B}|^{q}\unicode[STIX]{x1D714}(x)^{q}\,dx\bigg)^{1/q}<\infty .\end{eqnarray}$$ As applications, we characterize these spaces by the boundedness of commutators of some operators on weighted Lebesgue spaces.
Persistence and gender differences in protection against severe fever with thrombocytopaenia syndrome virus with natural infection: a 4-year follow-up and mathematical prediction study
Authors: Qi R. , Huang Y.T. , Yu X.J.
Published: January 2019

Severe fever with thrombocytopaenia syndrome (SFTS) is an emerging infectious disease discovered in 2010 and has a case fatality as high as 30%. We intended to study the immune protection conferred by SFTS with natural infection. We collected and analysed 4-year follow-up data to study the characteristics of neutralising antibodies against SFTS virus (SFTSV). The 50% plaque reduction neutralisation test was used for the detection of neutralising antibodies against SFTSV. Geometric mean titres (GMTs) and proportions of patients with a protective titre were analysed, and the persistence of protection was predicted. The titre of antibodies declined yearly in the 4-year study period. Approximately 3 months after infection, the GMT was 143 (95% confidence interval (CI): 89–231), and 100% of patients had a protective titre. In the fourth year, the GMT declined to 53 (95% CI: 37–76), and 95% of patients had a protective titre. The titre was higher in females than in males. On average, the protection offered by neutralising antibodies against SFTSV could last as long as 9 years. The durations of protection were different for different initial titres. The characteristics of neutralising antibodies can be used as a reference for the vaccination doses and schedules of forthcoming vaccines.
China, India, and International Law: A Justice Based Vision Between the Romantic and Realist Perceptions
Authors: SORNARAJAH Muthucumaraswamy , WANG Jiangyu
Published: January 2019

This paper aims to build an analytical framework and a research agenda for a study of the potential impact of the rise of China and India on international law. In the light of the possibility that the two states may, together or individually, make changes in international law and shift it from its present Europe-America moorings, this paper attempts to analyze and answer three topics: (1) the common and different stances of China and India on the existing international legal order; (2) the changes China and India have sought to the international status quo; and (3) the contributions that have been or could be brought by China and India to the development of international law and their implications for the future. It proposes an analytical framework in which these questions are viewed through two lenses: the romantic vision and the realist vision.
A Reflection on Crucial Periods in 50 Years of Social Psychology (in	Germany)
Authors: Corcoran Katja , Häfner Michael , Kauff Mathias , Stürmer Stefan
Published: January 2019

Abstract. In this article, we reflect on 50 years of the journal Social Psychology. We interviewed colleagues who have witnessed the history of the journal. Based on these interviews, we identified three crucial periods in Social Psychology’s history, that are (a) the early development and further professionalization of the journal, (b) the reunification of East and West Germany, and (c) the internationalization of the journal and its transformation from the Zeitschrift für Sozialpsychologie to Social Psychology. We end our reflection with a discussion of changes that occurred during these periods and their implication for the future of our field.
Volcanic‐Tectonic Structure of the Mount Dent Oceanic Core Complex in the Ultraslow Mid‐Cayman Spreading Center Determined From Detailed Seafloor Investigation
Authors: Haughton G. A. , Hayman N. W. , Searle R. C. , Le Bas T. , Murton B. J.
Published: January 2019

The flanks of the ultraslow‐spreading Mid‐Cayman Spreading Center (MCSC) are characterized by domal massifs or oceanic core complexes (OCCs). The most prominent of these, Mount Dent, comprises lower‐crustal and upper‐mantle lithologies and hosts the Von Damm vent field ~12 km west of the axial deep. Here, presented autonomous underwater vehicle‐derived swath sonar (multibeam) mapping and deep‐towed side‐scan sonar imagery lead to our interpretation that: (i) slip along the OCC‐bounding detachment fault is ceasing, (ii) the termination zone, where detachment fault meets the hanging wall, is disintegrating, (iii) the domed surface of the OCC is cut by steep north‐south extensional faulting, and (iv) the breakaway zone is cut by outward facing faults. The Von Damm vent field and dispersed pockmarks on the OCC's south flank further suggest that hydrothermal fluid flow is pervasive within the faulted OCC. On the axial floor of the MCSC, bright acoustic backscatter and multibeam bathymetry reveal: (v) a volcanic detachment hanging wall, (vi) a major fault rifting the southern flank of Mount Dent, and (vii) a young axial volcanic ridge intersecting its northern flank. These observations are described by a conceptual model wherein detachment faulting and OCC exhumation are ceasing during an increase in magmatic intrusion, brittle deformation, and hydrothermal circulation within the OCC. Together, this high‐resolution view of the MCSC provides an instructive example of how OCCs, formed within an overall melt‐starved ultraslow spreading center, can undergo magmatism, hydrothermal activity, and faulting in much the same way as expected in magmatically more robust slow‐spreading centers elsewhere.
Meridional Gulf Stream Shifts Can Influence Wintertime Variability in the North Atlantic Storm Track and Greenland Blocking
Authors: Joyce Terrence M. , Kwon Young‐Oh , Seo Hyodae , Ummenhofer Caroline C.
Published: January 2019

After leaving the U.S. East Coast, the northward flowing Gulf Stream (GS) becomes a zonal jet and carries along its frontal characteristics of strong flow and sea surface temperature gradients into the North Atlantic at midlatitudes. The separation location where it leaves the coast is also an anchor point for the wintertime synoptic storm track across North America to continue to develop and head across the ocean. We examine the meridional variability of the separated GS path on interannual to decadal time scales as an agent for similar changes in the storm track and blocking variability at midtroposphere from 1979 to 2012. We find that periods of northerly (southerly) GS path are associated with increased (suppressed) excursions of the synoptic storm track to the northeast over the Labrador Sea and reduced (enhanced) Greenland blocking. In both instances, GS shifts lead those in the midtroposphere by a few months.
Modeling the Quasi‐Trapped Electron Fluxes From Cosmic Ray Albedo Neutron Decay (CRAND)
Authors: Xiang Zheng , Li Xinlin , Selesnick R. , Temerin M. A. , Ni Binbin , Zhao Hong , Zhang Kun , Khoo Leng Ying
Published: January 2019

Recently, cosmic ray albedo neutron decay (CRAND) has been identified as the main source of relativistic electrons measured at the inner edge of inner radiation belt. Here we introduce a drift‐source model that includes azimuthal drift and a CRAND electron source to simulate the quasi‐trapped electron distribution measured by the DEMETER satellite during 20–30 April 2010. The simulated longitude distribution of quasi‐trapped electron fluxes at the inner edge of inner radiation belt successfully reproduces the DEMETER observations, confirming CRAND as the main source for these electrons. Furthermore, a comparison of the energy spectrum and the L distribution of the quasi‐trapped relativistic electrons between simulations and observations further suggests that CRAND is likely the dominant source for 300–700‐keV quasi‐trapped electrons at L < 2 and L ≈ 3.
Cosmogenic Isotopes Unravel the Hydrochronology and Water Storage Dynamics of the Southern Sierra Critical Zone
Authors: Visser A. , Thaw M. , Deinhart A. , Bibby R. , Safeeq M. , Conklin M. , Esser B. , Van der Velde Y.
Published: January 2019

One of the principal questions in hydrology is how and when water leaves the critical zone storage as either stream flow or evapotranspiration. We investigated subsurface water storage and storage selection of the Southern Sierra Critical Zone Observatory (California, USA) within the age‐ranked storage selection framework, constrained by a novel combination of cosmogenic radioactive and stable isotopes: tritium, sodium‐22, sulfur‐35, and oxygen‐18. We found a significant positive correlation between tritium and stream flow rate and between sulfur‐35 and stream flow rate, indicating that the age distribution of stream flow varies with stream flow rate. Storage selection functions that vary with stream flow rate are better able to reproduce tritium concentrations in stream flow than functions that are constant in time. For the Southern Sierra Critical Zone, there is a strong preference to discharge the oldest water in storage during dry conditions but only a weak preference for younger water during wet conditions. The preference of evapotranspiration for younger water, constrained by oxygen‐18 in stream water, is essential to parameterize subsurface storage but needs to be confirmed by isotopic or other investigations of evapotranspiration. This is the first study to illustrate how a combination of cosmogenic radioactive isotopes reveals the hydrochronology and water storage dynamics of catchments, constrains the subsurface architecture of the critical zone, and provides insight into landscape evolution.
With Shutdown Over for Now, Science Agencies Pick Up the Pieces
Authors: Showstack Randy
Published: January 2019

Agencies and employees weigh the impact of the shutdown.
Downregulation of G2/mitotic-specific cyclinB1 triggers autophagy via AMPK-ULK1-dependent signal pathway in nasopharyngeal carcinoma cells
Authors: Xie Xianhe , Lin Wanzun , Zheng Weili , Chen Ting , Yang Haitao , Sun Lijun , Huang Fei , Wang Zili , Lin Heng , Chen Long , Liu Jun , Yang Liyan
Published: January 2019

CyclinB1 is a regulatory protein involved in mitosis. Multiple lines of evidence indicate that cyclinB1 depletion constrains proliferation and induces apoptosis in human tumor cells. The cells become susceptible to suffer a critical situation when cyclinB1 is downregulated. Autophagy is a major intracellular degradation system that recycles nutrients, removes damaged organelles, and promotes cell survival under stressful conditions, whereas the role of autophagy in cyclinB1-deprived neoplastic cell as well as the underlying molecular mechanism remains obscure. Here we pioneeringly elaborated that specific knockdown of cyclinB1 triggered autophagy via AMPK-ULK1-dependent signal pathway through the elevation of ROS, rather than ATP in the cell lines of CNE-1 and CNE-2. Moreover, ROS scavengers demonstrated that the observed effect of cyclinB1 silencing on AMPK phosphorylation was ROS dependent. Additionally, double knockdown of AMPK and cyclinB1 evidently abrogated cyclinB1 silencing-induced autophagy. Summarily, this study first revealed that downregulation of cyclinB1 induced autophagy via AMPK-ULK1-dependent signal pathway, which represents a key step toward unveiling the mechanism how cell cycle checkpoint proteins regulate autophagy.
Gauge ambiguities imply Jaynes-Cummings physics remains valid in ultrastrong coupling QED
Authors: Stokes Adam , Nazir Ahsan
Published: January 2019

Ultrastrong-coupling between two-level systems and radiation is important for both fundamental and applied quantum electrodynamics (QED). Such regimes are identified by the breakdown of the rotating-wave approximation, which applied to the quantum Rabi model (QRM) yields the apparently less fundamental Jaynes-Cummings model (JCM). We show that when truncating the material system to two levels, each gauge gives a different description whose predictions vary significantly for ultrastrong-coupling. QRMs are obtained through specific gauge choices, but so too is a JCM without needing the rotating-wave approximation. Analysing a circuit QED setup, we find that this JCM provides more accurate predictions than the QRM for the ground state, and often for the first excited state as well. Thus, Jaynes-Cummings physics is not restricted to light-matter coupling below the ultrastrong limit. Among the many implications is that the system’s ground state is not necessarily highly entangled, which is usually considered a hallmark of ultrastrong-coupling.
The cholesterol biosynthesis pathway regulates IL-10 expression in human Th1 cells
Authors: Perucha Esperanza , Melchiotti Rossella , Bibby Jack A , Wu Wing , Frederiksen Klaus Stensgaard , Roberts Ceri A. , Hall Zoe , LeFriec Gaelle , Robertson Kevin A. , Lavender Paul , Gerwien Jens Gammeltoft , Taams Leonie S. , Griffin Julian L. , de Rinaldis Emanuele , van Baarsen Lisa G. M. , Kemper Claudia , Ghazal Peter , Cope Andrew P.
Published: January 2019

The mechanisms controlling CD4+ T cell switching from an effector to an anti-inflammatory (IL-10+) phenotype play an important role in the persistence of chronic inflammatory diseases. Here, we identify the cholesterol biosynthesis pathway as a key regulator of this process. Pathway analysis of cultured cytokine-producing human T cells reveals a significant association between IL-10 and cholesterol metabolism gene expression. Inhibition of the cholesterol biosynthesis pathway with atorvastatin or 25-hydroxycholesterol during switching from IFNγ+ to IL-10+ shows a specific block in immune resolution, defined as a significant decrease in IL-10 expression. Mechanistically, the master transcriptional regulator of IL10 in T cells, c-Maf, is significantly decreased by physiological levels of 25-hydroxycholesterol. Strikingly, progression to rheumatoid arthritis is associated with altered expression of cholesterol biosynthesis genes in synovial biopsies of predisposed individuals. Our data reveal a link between sterol metabolism and the regulation of the anti-inflammatory response in human CD4+ T cells.
Dual RNA-seq identifies human mucosal immunity protein Mucin-13 as a hallmark of Plasmodium exoerythrocytic infection
Authors: LaMonte Gregory M. , Orjuela-Sanchez Pamela , Calla Jaeson , Wang Lawrence T. , Li Shangzhong , Swann Justine , Cowell Annie N. , Zou Bing Yu , Abdel-Haleem Mohamed Alyaa M. , Villa Galarce Zaira Hellen , Moreno Marta , Tong Rios Carlos , Vinetz Joseph M. , Lewis Nathan , Winzeler Elizabeth A.
Published: January 2019

The exoerythrocytic stage of Plasmodium infection is a critical window for prophylactic intervention. Using genome-wide dual RNA sequencing of flow-sorted infected and uninfected hepatoma cells we show that the human mucosal immunity gene, mucin-13 (MUC13), is strongly upregulated during Plasmodium exoerythrocytic hepatic-stage infection. We confirm MUC13 transcript increases in hepatoma cell lines and primary hepatocytes. In immunofluorescence assays, host MUC13 protein expression distinguishes infected cells from adjacent uninfected cells and shows similar colocalization with parasite biomarkers such as UIS4 and HSP70. We further show that localization patterns are species independent, marking both P. berghei and P. vivax infected cells, and that MUC13 can be used to identify compounds that inhibit parasite replication in hepatocytes. This data provides insights into host-parasite interactions in Plasmodium infection, and demonstrates that a component of host mucosal immunity is reprogrammed during the progression of infection.
Publisher Correction: Z-ring membrane anchors associate with cell wall synthases to initiate bacterial cell division
Authors: Pazos Manuel , Peters Katharina , Casanova Mercedes , Palacios Pilar , VanNieuwenhze Michael , Breukink Eefjan , Vicente Miguel , Vollmer Waldemar
Published: January 2019

The original version of this Article contained errors in Figures 1 and 3. In Fig. 1b, the label ‘IP-PBP3’ above the second of the three blots incorrectly read ‘IP-PBP1B’. In Fig. 3b, the label ‘PBP1B’ under the first bar of each chart incorrectly read ‘PBP1A’. These errors have been corrected in both the PDF and HTML versions of the Article.
Mitotic chromosome binding predicts transcription factor properties in interphase
Authors: Raccaud Mahé , Friman Elias T. , Alber Andrea B. , Agarwal Harsha , Deluz Cédric , Kuhn Timo , Gebhardt J. Christof M. , Suter David M.
Published: January 2019

Mammalian transcription factors (TFs) differ broadly in their nuclear mobility and sequence-specific/non-specific DNA binding. How these properties affect their ability to occupy specific genomic sites and modify the epigenetic landscape is unclear. The association of TFs with mitotic chromosomes observed by fluorescence microscopy is largely mediated by non-specific DNA interactions and differs broadly between TFs. Here we combine quantitative measurements of mitotic chromosome binding (MCB) of 501 TFs, TF mobility measurements by fluorescence recovery after photobleaching, single molecule imaging of DNA binding, and mapping of TF binding and chromatin accessibility. TFs associating to mitotic chromosomes are enriched in DNA-rich compartments in interphase and display slower mobility in interphase and mitosis. Remarkably, MCB correlates with relative TF on-rates and genome-wide specific site occupancy, but not with TF residence times. This suggests that non-specific DNA binding properties of TFs regulate their search efficiency and occupancy of specific genomic sites.