bluuebunny/crossref_metadata_2025 huggingface dataset:
IMPLEMENTASI QUICK RESPONSE CODE UNTUK PENDUKUNG SISTEM INFORMASI PRESENSI
Authors: Kusumawardhani Nur Indah , Fajri Ika Nur
Published: December 2024

The development of science and technology (IPTEK) and information is a reality that must be faced by everyone, including educational institutions and government agencies. One example is the use of information technology in schools to facilitate the work of educators and education personnel. However, in primary, secondary, and higher education, many still use manual attendance. SMK Negeri 2 Klaten also experienced this problem. To overcome this problem, a website was designed to record, report, and monitor student attendance using the QR Code scanning method. This research uses the waterfall method which includes Requirements Analysis, System Design, Implementation, Integration and Testing, and Operation and Maintenance. The results showed that a website-based attendance information system can speed up and simplify the attendance process, reduce errors, and increase efficiency. It is proven that after testing the QR Code based on the scanning distance, the scanning response speed only requires a delay of 0.94 seconds at an effective distance of 20 cm. In conclusion, the application of information technology in the attendance process at SMK Negeri 2 Klaten can improve the quality and efficiency of attendance management.
Gambaran Hasil Autopsi di RS Bhayangkara Tingkat III Manado Periode Januari 2020 - Desember 2022
Authors: Setiawan Dwipania P. , Siwu James F. , Kristanto Erwin G.
Published: December 2024

Abstract: The rise in cases of natural or unnatural deaths in Manado has led to suspicions about the cause of death; therefore, the police will ask for help from forensic doctors to carry out autopsies. This study aimed to obtain the autopsy description, especially at Rumah Sakit Bhayangkara Tingkat III Manado for the period of January 2020 - December 2022. This was a retrospective and descriptive study using data from the visum et repertum results. The results showed that there were 97 autopsy cases; 21 of which were excluded. The most frequent cases were in 2021 and 2022, namely 28 cases (36.84%). Most cases were male (89.47%). The largest age group was early adulthood (26-35 years) (28.95%). The most common cause of death was unnatural death (92.1%), with sharp violent death cases (92.1%). For natural deaths, cardiovascular disease and lung disease were the highest (each of 50%). In conclusion, autopsies are often performed on men in early adulthood (26-35 years), with unnatural deaths in cases of sharp violence, while the most common natural deaths are cardiovascular and lung diseases.
Keywords: autopsy; cause of death; sharp violence; cardiovascular disease; lung disease
  
Abstrak: Maraknya kasus kematian wajar atau tidak wajar di Manado menyebabkan munculnya kecurigaan tentang sebab kematian sehingga dari pihak kepolisian akan meminta bantuan ahli dokter forensik untuk dilakukan autopsi. Penelitian ini bertujuan untuk mendapatkan gambaran autopsi terutama di Rumah Sakit Bhayangkara Tingkat III Manado periode Januari 2020 – Desember 2022. Jenis penelitian ialah deskriptif retrospektif menggunakan data hasil visum et repertum. Hasil penelitian mendapatkan 97 kasus yang di autopsi; 21 di antaranya dieksklusi. Kasus terbanyak pada tahun 2021 dan 2022 yaitu 28 kasus (36,84%). Sebagian besar kasus berjenis kelamin laki-laki (89,47%). Kelompok usia terbanyak yaitu dewasa awal (26-35 tahun) (28,95%). Penyebab kematian  terbanyak ialah kematian tidak wajar (92,1%), dengan kasus kematian kekerasan tajam (92,1%). Untuk kematian wajar didapatkan penyakit kardiovaskuler dan penyakit paru yang terbanyak (masing-masing 50%). Simpulan penelitian ini ialah autopsi yang sering dilakukan pada jenis kelamin laki-laki, usia dewasa awal (26-35 tahun), dengan kematian tidak wajar kasus kekerasan tajam, sedangkan pada kematian wajar penyebabnya ialah penyakit kardiovaskuler dan penyakit paru yang terbanyak.
Kata kunci: autopsi; sebab kematian; kekerasan tajam; penyakit kardiovaskuler; penyakit paru
Analisis Penetrasi Sosial di Dunia Maya (Studi Peran Moderator di TikTok Live DJ Ronald)
Authors: Gunawan Aloysius Bernanda , Sigit Ridzki Rinanto
Published: December 2024

TikTok video sharing based social media is one of the most popular social media during the pandemic until now. TikTok facilitates the needs of its users to share and actualize themselves personally in mass media. This study aims to understand the stages of social penetration that can occur in online communities on TikTok Live and communities in the real world and the role of moderators in this stage. This research was conducted qualitatively by conducting observations and in-depth interviews with the parties in the community, namely content creators, moderators and audiences. The results of this study found that each party plays a different role in each stage of social penetration and can carry out acceleration and deceleration processes to speed up or slow down each stage for the benefit of the community. The findings of this study are expected to enrich the literature related to the theory of social penetration in cyberspace and the roles of the parties on TikTok.
Sistem Informasi Penjualan Roti di Toko Mitha Bakery Palu Menggunakan Framework Laravel
Authors: Putra Alviano Yossia , Beeh Yos Richard
Published: December 2024

Mitha Bakery is a Bakery that offers various types of bread, including white bread and brown bread, with undoubted quality. Established in early 2020 in Palu, Central Sulawesi, this shop has experienced a significant increase in sales, from 80 loaves per day in 2022 to more than 300 loaves per day in 2023. To improve service quality, Mitha Bakery designed a sales system web-based using the Laravel Framework and MySQL as the data base. This system is designed to make it easier for customers to obtain information about products and place orders without having to come directly to the shop. This research aims to design and implement an effective and efficient sales system, as well as providing practical benefits for stores and academic contributions through real applications of programming knowledge. With this system, obstacles related to distance, time and limited facilities can be overcome, so that customers can make purchases more comfortably and quickly.
Perbandingan Algoritma Decision Tree, ID3, dan Random Forest dalam Klasifikasi Faktor-Faktor yang Mempengaruhi Karier Mahasiswa Ilmu Komputer
Authors: Hartama Dedy , Amalya Nanda
Published: December 2024

This study aims to compare the performance of three classification algorithms, namely Decision Tree, ID3, and Random Forest, in identifying factors that influence the careers of computer Science students. These algorithms are applied to a dataset that includes various student attributes, such as GPA, programming skills, and completed projects. The results show that Random Forest provides more accurate and stable prediction results than Decision Tree and ID3, especially in reducing the risk of overfitting. Students with high skills in Python and SQL and who focus on software development tend to choose a career in Software Engineering. While those involved in AI/ML-based projects tend to choose Data Science. The conclusions of this study provide valuable insights for educational institutions to design more effective career development strategies for students.
Analisis Framing Kontroversi Pada Olimpiade Paris 2024 di CNN Indonesia dan Republika
Authors: Akbar Fazriel Irviana , Nanda Ertika
Published: December 2024

The 2024 Paris Olympics has had controversies such as a boxer suspected of being transgender taking part in the Olympics and rules prohibiting the use of the hijab for French athletes. The aim of this research is to analyze the framing of controversy at the 2024 Paris Olympics in the online media CNN Indonesia and Republika. This research uses a qualitative analysis method with Robert N Entman's framing analysis which consists of problem definition, source of the problem, moral decisions taken, and problem resolution. This research uses articles released from 18 July to 1 August 2024 on CNN Indonesia and Republika. The results of this research explain that the difference between CNN Indonesia and Republika is that CNN Indonesia tends to be neutral and provides justification for decisions taken by related parties. Meanwhile, Republika emphasized criticism and highlighted aspects of discrimination in these two issues. The difference in reporting on the controversial issue of female boxers is that CNN Indonesia is more inclined to support these athletes and the role of athletes by emphasizing personal rights that free athletes to take part in any competition, whereas in Republika they are more likely to discuss criticizing policies taken by certain authorities. On the issue of banning the use of the hijab by French Muslim female athletes, CNN Indonesia emphasized the word proselytism which France wanted to prevent and explained that the rule forbidding the use of the hijab only applies to France, while Republika explained that this rule exists because of Islamophobia and racism, thus demanding that the IOC this rule can be omitted.
Analisis Instagram terhadap Gaya Hidup dan Pola Komunikasi pada Remaja Karang Taruna Cempaka Putih, Kecamatan Gondangrejo, Karanganyar
Authors: Yuliana Margaretha Evi , Arini Dhefilyn Wahyu Widia , Renjani Inenimas Arya
Published: December 2024

The advancement of information and communication technology, particularly through social media platforms like Instagram, has a significant influence in shaping the lifestyle and communication patterns of teenagers. This study aims to analyze how teenagers in the Karang Taruna Cempaka Putih youth organization in Gondangrejo District, Karanganyar, use Instagram as a medium for self-expression to showcase their lifestyle and create new dynamics in interaction and communication in this digital era. With the development of social media, Instagram has become not only a platform for sharing photos and videos but also a space for teenagers to build their identity, explore creativity, and connect with their social environment. A descriptive qualitative method was selected as the research method for this study by observing Instagram accounts of seven 22-year-old teenagers. Data were collected through screenshots of Instagram Stories, feeds, reels, and comments, capturing activities such as vacations, nature adventures, cafe visits, significant celebrations, and participation in campus organizations. This demonstrates that social media has become a space for teenagers to express themselves. Communication patterns on Instagram are reflected in creative captions and interactive comments, creating a relaxed and dynamic atmosphere. These patterns show that Instagram is an effective medium for building communication styles. The implications of this study include an increased understanding of socio-cultural dynamics, the influence of social media on identity formation, and the development of communication skills.
Perancangan UI/UX Aplikasi Stunting Your Buddy dengan Metode User-Centered Design
Authors: Putra Anak Agung Adi Wiryya , Wirdianthi Ni Luh Risma Putri , Azzaky Renald Kevin
Published: December 2024

The aim of this study is to design a mobile application that can assist in handling stunting in Panjer Village, Bali. Stunting is a condition where a child cannot grow to their optimal height according to the height of a child of their age. In this digital era, education can be conducted through various platforms, such as applications that are now commonly used. Based on a field survey that has been conducted by researching the needs of users one and two, Your Buddy will be designed to help provide education for young women about stunting prevention. Furthermore, this application will serve as an intermediary for pediatric specialists to provide education regarding stunting. This research focuses on an application that will function for stunting prevention education, requiring improvements in terms of appearance (UI) and usability (UX) to make it more appealing and user-friendly. To achieve this goal, this study will utilize the User Centered Design (UCD) method. The UCD method consists of four stages: specify the context of use, specify user and organizational requirements, produce design solutions, and evaluate design against user requirements. After testing several potential users, a final SUS score of 87.5 was obtained, which falls into point B with an Excellent category. The design of the Your Buddy application is proven to have quality that meets user expectations, but in the future, it is recommended to add AI features and increase the number of respondents to expand this research.
Optimalisasi Strategi Komunikasi Pemasaran Perusahaan Startup PT. Tala Bumi Group dalam Bisnis Franchise Food and Beverages
Authors: Amelia Nabila Syifa , Yudhistira Nurfian
Published: December 2024

This study aims to optimize the marketing communication strategy employed by PT. Tala Bumi Group, a startup in the food and beverage (F&B) franchise industry. This sector has been experiencing rapid growth in Indonesia, driven by a rising population and increased market demand. However, the coffee shop segment faces significant challenges due to heightened competition. This research utilizes a descriptive qualitative method with a case study approach, involving in-depth interviews with stakeholders and secondary data analysis to explore the 7P marketing mix components: Product, Price, Place, Promotion, People, Process, and Physical Evidence. The main findings indicate that PT. Tala Bumi Group successfully leverages digital communication—particularly through social media—to enhance brand visibility and market reach. In terms of the 7P strategy, the company has differentiated its product offerings and strengthened promotional activities, including influencer partnerships aimed at appealing to younger demographics. However, further optimization is needed in pricing strategy to align with shifting consumer behavior, as well as in customer loyalty initiatives to remain competitive. Enhancements in customer service processes and physical elements (e.g., store design) also emerged as key areas of focus. These findings contribute to the F&B franchise industry by providing strategic insights adaptable to dynamic market demands and competitive pressures.
Desain dan Prototipe Integrasi IoT dalam Pertanian Hidroponik Cerdas Berbasis Energi Terbarukan
Authors: Wardhana Agus Salim , Ferdiansyah Muhammad , K Siti Kholifah
Published: December 2024

This research aims to develop a prototype for an Internet of Things-based automation system powered by renewable energy, specifically solar panels, to enhance the efficiency and productivity of hydroponic farming. The study addresses critical challenges, including high energy costs and the intensive monitoring demands of conventional hydroponic systems. The experimental methodology involves designing hardware featuring Arduino Uno as the central control unit, environmental sensors (DHT22) for real-time monitoring, and automated actuators such as water pumps, fans, and LED lights. The system integration process encompasses linking the hardware to an IoT interface, followed by rigorous functional testing to evaluate system stability, energy efficiency, and operational performance under varying environmental conditions. The results demonstrate that the prototype successfully operates the entire hydroponic system using energy exclusively from solar panels, eliminating reliance on conventional electricity. The system achieves precise control over critical plant growth parameters such as temperature, humidity, and lighting, with high operational stability observed during trials. This research makes a notable contribution by innovatively integrating IoT, automation, and renewable energy, thereby enhancing energy efficiency while delivering a sustainable and environmentally friendly hydroponic farming solution. The findings have significant practical implications, particularly for implementation in remote areas with limited access to electricity. Furthermore, the study paves the way for future developments, including applications in other agricultural systems and the integration of artificial intelligence to enhance predictive analytics and automated control.
Representasi Liberalisme dalam Film Gran Turismo (Analisis Semiotika John Fiske)
Authors: Prasetyo Diky Rizky , Nanda Ertika
Published: December 2024

The research aims to understand how the representation of struggle is depicted through the journey faced by the main character in the film Gran Turismo. This research employs a qualitative method with a descriptive approach, as well as a semiotic analysis method by John Fiske using his Three Codes of Television, which divides social codes into three levels: the level of reality, the level of representation, and the level of ideology. Data collection was conducted through non-participant observation, with documentation in the form of screen captures. The results of this research include analyses of the level of reality, the level of representation, and the level of ideology. The level of reality is derived from several aspects, including gesture codes, expression codes, conversation codes, and behavior codes. The analysis of the level of reality in this film shows that the character Jann is portrayed as having a focused and patient attitude when facing problems. The level of representation analyzes scenes through audiovisual elements such as camera techniques, lighting, editing, music, and sound. The analysis of the level of representation in this film highlights the importance of aspects that support the film's appearance, making it more engaging and effectively conveying its message. The level of ideology analyzes the story presented in the film to determine the ideological concepts contained within it. The analysis of the level of ideology in this film reveals that the struggles of the main character against the currents of simplicity to become a professional racer illustrate that the film conveys a liberalism ideology, where liberalism represents the concept of individual freedom, particularly to become what one desires.
Pengembangan Antarmuka Website Kebugaran Fitme untuk Mendukung Pola Hidup Sehat dengan Penerapan Metode Human-Centered Design
Authors: Putra Anak Agung Adi Wiryya , Wanditya I Made Dedy , Fhadillah Moh. Lukman Hakim
Published: December 2024

Healthy living is often associated with achieving an ideal body weight, which is the goal of many people who are overweight. Therefore, various methods are carried out to achieve the desired body weight. FitMe is present as a website designed to make it easier for the public to get information related to the importance of maintaining an ideal body weight. FitMe equipped with various features such as personalized workout programs, diet and nutrition monitoring, exercise trackers, daily journal entries, fitness consultation, comprehensive fitness education materials, as well as a marketplace for the purchase of products such as protein milk and nutritious foods. This research uses the Human Centered Design method, which is an approach that focuses on all users, both potential and not. Human Centered Design is determined in this research because this method focuses on a wider range of users. Design testing is carried out using the UEQ method on 20 respondents and the results obtained are Excellent, which means that the design of Fitme has met the user's criteria and there is no need to undergo a redesign process.
Optimasi Produksi Donat di Usaha O’Om Donuts untuk Mencapai Keuntungan Maksimal dengan Program Linier Metode Grafik
Authors: Jaya Asirman , Sukma Silvia Antana , Utomo Pradita Eko Prasetyo , Khaira Ulfa
Published: December 2024

Small and Medium Enterprise (SME) in the culinary sector, such as O'om Donuts, explore innovation in unique donut products. Despite creating enticing variations like Baby Donuts and Donuts, O'om Donuts faces challenges in determining the optimal production to maximize profits. This research employs the linear programming graphic method at O'om Donuts' production facility in Kota Jambi to design an efficient production strategy and minimize production costs. The research methodology involves observation, interviews, and quantitative descriptive analysis. The results indicate that the optimal solution involves producing 300 Baby Donuts and 70 Big Donuts from limited resources, yielding a maximum profit of Rp315,000. The implementation of linear programming in O'om Donuts' production is expected to enhance production efficiency and accommodate product variations, creating maximum profits for MSMEs in the diverse culinary market.
Klasifikasi Penyakit Migrain dengan Metode Naïve Bayes pada Dataset Kaggle
Authors: Yuichi Michael , Susetyo Yeremia Alfa
Published: December 2024

Migraine is one of the most common neurological diseases in society and has a significant disability impact. According to the Global Burden of Disease Study, migraine is one of the most common neurological disorders in the world, with a greater disability burden than other neurological disorders. In data science, data classification plays an important role in determining the category or class of an object based on a number of available classes. One frequently used classification method is Naïve Bayes, which utilizes mathematical probabilities with the assumption that the decision made is accurate based on the given data. This research develops a classification model using the Naïve Bayes algorithm to predict and classify migraine patient data. This model produces classification values with an accuracy of 88.51% when training from 280 train data given and 89.02% when testing from 120 test data given.  The classification results can support the medical world in diagnosing migraine types more accurately, optimizing treatment, saving health costs, and becoming the basis for further research and development in the field of neurology.
Effectiveness of Gedong Gincu Mango Leaf Extract Gel (Mangifera indica L. var. Gedong gincu) on Cut Wound Healing in Male White Rats (Rattus norvegicus) of the Wistar Strain
Authors: Loren Azzahro Maharani , Wirandoko Ignatius Hapsoro , Marfuati Sri
Published: December 2024

Background: The Indonesia Basic Health Research data show the prevalence of wounds including incision/scratches/stab wounds reaches 20.1%. Natural herbal products play an important role in the wound healing process functioning as anti-inflammatories, antioxidants, antimicrobials, and collagen formation. Mango leaves are often considered waste even though they have many health benefits with the high content of coactive compounds, such as alkaloids, flavonoids, tannins, and saponins which are good for cut wound healing. The use of gel is more stable and controlled release compared to other topical preparations. Gedong Gincu mangoes originating from West Java have unique properties and they are marketed widely in some areas including Cirebon.
Aims: This study aims to identify the most effective concentration of Gedong Gincu mango leaf extract on cut wound healing in male white rats (Rattus norvegicus) of the Wistar Strain.
Methods: This study used a post-test-only control group design. The extract gel used three levels of concentration, namely 40%, 50%, and 60%. The positive control used 10% povidone iodine while the negative control used a gel base. The gel was applied to the cut wound twice a day for 14 days.
Results: The average length of the cut wound was 0.916 cm, 0.912 cm, and 1.050 cm for concentration levels of 40%, 50%, and 60%. For the positive and negative controls, it reached 0.996 cm and 0.702 cm respectively. This indicates no significant difference in the length of the cut wound with a p-value of 0.121 (p>0.05). The wound healing process was effective at a concentration level of 60% as indicated by the disappearance of erythema and edema.
Conclusion: Mango leaf extract gel (Mangifera indica L.var. Gedong Gincu) is effective in healing cut wounds with the disappearance of erythema and edema in male white rats (Rattus norvegicus) Wistar strain with a concentration of 60%.
Received: 25 September 2024  |  Reviewed: 19 October 2024  | 
Revised: 30 November 2024  |  Accepted: 15 December 2024.
Demographics and Histopathological Characteristics of Lung Cancer Patients in Cirebon District, Indonesia (2021-2023)
Authors: Sulaeman Syakira Puteri , Fitrie Alya Amila , Sedayu Sedayu
Published: December 2024

Background: Based on the Global Burden of Cancer Study (GLOBOCAN) in 2020, In the world, lung cancer is the first cause of death. In Indonesia, lung cancer is the third highest.  Lung cancer is classified into two cell types: Small Cell Lung Cancer and Non-Small Cell Lung Cancer. There are two types of Non-Small Cell Lung Cancer: squamous cell carcinoma, adenocarcinoma, and large cell carcinoma.
Aims: To determine the demographics and histopathological characteristics of lung cancer patients in Cirebon District (2021-2023).
Methods: This research employed a descriptive observational method. The data were collected from general hospitals’ medical records of lung cancer patients at RSUD Waled Cirebon and RSUD Arjawinangun in 2021-2023 using the total sampling technique. There were 69 respondents met the inclusion criteria for this recent study.
Results: In this study, there were 68.1% of patients aged from 46 to 70 years, and the majority were male (66.7%). The most common cancer cell type was adenocarcinoma (69.6%). Most patients did not have information regarding occupational data (68.1%), smoking history (98.6%), family history (98.6%), and staging (89.9%) included in their medical records.
Conclusion: The analysis showed that most lung cancer patients are aged 46-70 years and male incidences in lung cancer patients were higher. The most common type of histopathological is adenocarcinoma. Related to occupational data, smoking history, family history, and staging could not be concluded because they were not included in the medical record.
Received: 25 September 2024  |  Reviewed: 19 October 2024  | 
Revised: 30 November 2024  |  Accepted: 12 December 2024.
Correlation between Hypertension and the Severity of Diabetic Retinopathy in Diabetes Mellitus Patients at Waled Regional General Hospital: A Cross-Sectional Study
Authors: Trinanda Syifa Khaerunisa , Sisprihattono Boyke , Astuti Widi
Published: December 2024

Background: Diabetes mellitus is a metabolic disorder characterized by elevated blood sugar levels and resulting from deviations in either insulin secretion, insulin action, or both. Prolonged hyperglycemia can lead to various complications, including diabetic retinopathy. The main risk factors for developing diabetic retinopathy are uncontrolled diabetes mellitus, hypertension, and dyslipidemia.
Aims: To determine the correlation between hypertension and the severity of diabetic retinopathy in diabetes mellitus patients at Waled Regional General Hospital, Cirebon, from 2020 to 2023.
Methods: This study used an analytical observational method with a cross-sectional design. We collected data from the medical records of patients with diabetic retinopathy at Waled Regional General Hospital from 2020 to 2023. This study employed total sampling as its sampling technique. We performed univariate analysis to determine the frequency distribution of the samples and bivariate analysis using the Spearman correlation test.
Results: Out of 50 diabetic retinopathy patients, the majority suffered from proliferative diabetic retinopathy (PDR), with 22 (44%) patients. The most common blood pressure level among the patients was grade 2 hypertension, with 19 (38%) patients. The bivariate analysis in this study showed a P-value of 0.091 and an r-value of 0.242.
Conclusion: There is no significant correlation between hypertension and the severity of diabetic retinopathy in diabetes mellitus patients at Waled Regional General Hospital from 2020 to 2023, with a positive correlation direction (p-value: 0.091 and r-value: 0.242).
Received: 25 September 2024  |  Reviewed: 16 October 2024  | 
Revised: 30 November 2024  |  Accepted: 12 December 2024.
The Effectiveness of Cassava Leaf (Manihot esculenta C.) Flavonoid Quercetin as Dengue Virus-1 Antivirus in Vitro
Authors: Rayasari Husnaya , Apriyanto Dadan Ramadhan , Brajawikalpa Rama Samara , Dewi Beti Ernawati
Published: December 2024

Background:  Dengue fever is a mosquito-borne disease that can cause severe symptoms and death, placing high burden on healthcare systems in tropical regions. Currently, there are no antiviral treatments. It has been proven that synthetic quercetin able to improve body performance and reduce the risk of infection as well as inhibit DENV replication. Cassava leaves (Manihot esculenta C.) contain anthocyanins (flavonoids) such as quercetin and it shows potential as antiviral agent as the synthetic as well.   
Aims: To describe the levels of self-compassion and procrastination among medical students and to examine how these factors relate to academic performance.
Methods: This experimental study used post-test only with control group design consisted of 13 treatment groups and 1 control group. Treatment group were divided into 6 different concentrations for inhibition test (50 µg/mL, 25 µg/mL, 12.5 µg/mL, 6.25 µg/mL, 3.125 µg/mL, 1.5 µg/mL) and 7 different concentrations  for cytotoxicity test (80 µg/mL, 40 µg/mL, 20 µg/mL, 10 µg/mL, 5 µg/mL, 2.5 µg/mL, 1.25 µg/mL). The control group was a negative control treated with 0.2% DMSO. Inhibition was assessed by Focus Forming Unit Assay and cytotoxic was assessed by number of Microtiter Tetrazolium Assay (MTT Assay). The statistical analysis used in this study were the Shapiro-Wilk test for normality test, Kruskal-Wallis test for hypothesis test, and post-hoc test to determine whether the groups studied in this research had significant differences from each other.
Results: The CC50 and IC50 values of quercetin of cassava leaf (Manihot esculenta C.) were found to be 3.44 μg/mL and 0.25 μg/mL, respectively, with an SI value of 123. Based on these results, it can be concluded that the flavonoid quercetin of cassava leaf (Manihot esculenta C.) exhibits selective properties in inhibiting the replication of DENV-1. Statistical analysis showed non-normal distribution (P<0.05), hypothesis test was accepted (P<0.05), and no significant differences between concentrations in the post-hoc test.
Conclusion: Quercetin of cassava leaf (Manihot esculenta C.) is effective as an antiviral agent against dengue serotype 1 strain New Guinea C in vitro.
Received: 25 September 2024  |  Reviewed: 15 October 2024  | 
Revised: 30 November 2024  |  Accepted: 15 December 2024.
Overview of COVID-19 Test Results (2021–2022) at the Laboratory of the Faculty of Medicine, Universitas Swadaya Gunung Jati, Cirebon, Indonesia
Authors: Febrianti Fitri Ayu , Khasanah Uswatun , Weni Mustika
Published: December 2024

Background: COVID-19 (Coronavirus Disease-19) is a respiratory infection caused by the SARS-CoV-2 virus. In 2020, the World Health Organization (WHO) declared COVID-19 a global pandemic due to the rapid rise in cases and mortality rates worldwide. The pandemic has impacted millions of people and continues to pose a significant global public health threat. Accurate diagnosis of the disease depends on laboratory testing, with RT-PCR widely recognized as the gold standard for confirming COVID-19.
Aims: To describe an overview of COVID-19 test results at Laboratory Faculty of Medicine, Universitas Swadaya Gunung Jati, Cirebon, Indonesia, from 2021-2022.
Methods: This study used a descriptive observational method. The sample was collected in July 2024 using a total sampling technique. The sample includes all 135,713 patients who had COVID-19 tests at Laboratory Faculty of Medicine Swadaya Gunung Jati Univesity between 2021 and 2022. Data were collected from medical records of COVID-19 test. The variables of this study include gender, age, and COVID-19 test results. A statistical analysis was used to determine frequency distribution.
Results: The results of the study showed that among the sample who tested for COVID-19, the majority are male (50.9%) and early adolescent age group (23.9%). RT-PCR test findings were positive in 16.3% of patients and negative in 83.7% of patients. Among PCR positive cases, the majority are female (17.4%), with seniors age groups >65 years accounting for 39.0%.
Conclusion: Most of the tested samples are males and early adolescent age groups, with more negative PCR results than positive ones. Among positive cases, the highest number was found in females and seniors age group. It is recommended that females and seniors age groups keep protected during COVID-19 outbreaks.
Received: 25 September 2024  |  Reviewed: 22 October 2024  | 
Revised: 30 November 2024  |  Accepted: 11 December 2024.
Glycated Hemoglobin Level and Body Mass Index Correlation with Peripheral Artery Disease in Patients with Type 2 Diabetes Mellitus at Waled Hospital, Cirebon, Indonesia
Authors: Auliya Tania , Amaliyah Nihayatul , Herdwiyanti Menik
Published: December 2024

Background: Peripheral Artery Disease (PAD) is a condition that reduces blood flow to the lower extremities and is primarily caused by atherosclerosis.  PAD is one of the complications of Diabetes Mellitus (DM). Diabetics have an 11.6 times more likely to develop PAD than those without diabetes. Glycated haemoglobin (HbA1c) levels >7% are at a higher risk of chronic complications. Obesity and overweight also raise the risk of developing PAD disease. However, research on the correlation between Body Mass Index (BMI) and PAD remains unclear and controversial.
Aims: To analyze the correlation between HbA1c levels and BMI with the incidence of Peripheral Artery Disease in patients with type 2 Diabetes Mellitus at Waled Hospital. 
Methods: This is an analytical observational study with a cross-sectional design. Data was collected on patients diagnosed with type 2 Diabetes Mellitus at the Internal Medicine Clinic at Waled Hospital in June - July 2024. A total sample of 77 was obtained using consecutive sampling. The inclusion criteria were type 2 DM, aged 19-60 years, and medical record data equipped with the HbA1c levels for at least the last 3 months prior to data collection. The exclusion criteria were patients with a history of diabetic ulcers, amputation and limb disability, Acute Coronary Syndrome, stroke, kidney failure, recurrent anaemia, and blood transfusions in the last 3 months. Primary data was gathered through an ABI examination, while secondary data was obtained from medical records. The data was analysed using the Spearman correlation test.
Results: Patients had poor HbA1c control (51.9%), moderate HbA1c control (29.9%) and good HbA1c control (18.2%), with the majority of patients had normal BMI (39%) followed by obese I (22.1%), overweight and obese II (16.9%). Our study showed that the distribution of PAD levels was severe (0%), moderate (3.9%), mild (44.2%), normal (46.8%), and arteriosclerotic (5.2%). The correlation test showed p-0.789 (p> 0.05) for HbA1c levels with PAD and p- 0.653 (p>0.05) for BMI with PAD.
Conclusion: There was no association between glycated hemoglobin or Body Mass Index values and the incidence of PAD in patients with type 2 Diabetes Mellitus at Waled Hospital, Cirebon, Indonesia.
Received: 25 September 2024  |  Reviewed: 21 October 2024  | 
Revised: 30 November 2024  |  Accepted: 11 December 2024.
Disinfection efficiency under conditions of ecological production of bee products
Authors: Rudenko Ye. V. , Sumakova N. V. , Rudenko O. P. , Sanin Yu. K. , Yemelianov A. V. , Kovalenko O. A.
Published: December 2024

The aim of the study was to investigate the effectiveness of disinfectants with different active ingredients in the ecological production of bee products in apiaries of different regions of Ukraine. The study was conducted in the production conditions of Kharkiv, Dnipro and Poltava regions in the period from 2012 to 2022. A total of 1,400 bee colonies of Carpathian and grey Ukrainian bee breeds were involved in the research. The bees were kept in standard hives, and the apiaries were of the honey-pollination type. During the research period, the apiaries were taken out for nomadic work within the specified regions during the active season. Continuous epizootic monitoring at apiaries allowed us to control and prevent the occurrence and course of infectious diseases of bees involved in the experiments during this period. For the clinical study of bee colonies, periodic examinations were carried out to identify the characteristic signs of infectious bee diseases, such as brood variegation, characteristic changes in the sealed and open brood of bees, the presence of dead larvae or pupae, which are characteristic of infectious diseases such as American and European rot, parasitic rot, ascospherosis, etc. During the experiment, about 2% of bee colonies were found to have certain clinical signs of diseases and peculiarities of their course in the form of mixed infectious diseases. To prevent the spread and emergence of new cases of diseases, a set of veterinary and sanitary measures was introduced and implemented, including forced and planned disinfection of honeycombs and hives, and treatment against infectious diseases of bees. Taking into account the modern requirements for the quality and safety of beekeeping products, several commercial preparations with different active ingredients were investigated — succinic acid, hydrogen peroxide and combined preparations with these active ingredients
Roversi, un libro aperto
Authors: Moliterni Fabio
Published: December 2024

Per assecondare l’eclettismo e la natura pluristratificata del lungo itinerario letterario di Roversi andrebbero individuate le tracce persistenti del sapere tragico che ne hanno condizionato la formazione giovanile, insieme con gli studi storici e filosofici che orientano il suo caratteristico storicismo eretico e non allineato. Sul piano più strettamente letterario, in questo intervento si ripercorrono anche i suoi rapporti con le tradizioni e con le avanguardie non soltanto italiane, oltre alla centralità che nell’opera di Roversi rivestono i romanzi e le relazioni tra poesia e prosa.
«Disunito fragoroso, incalzante»: l’irruzione del passato nella vita di un «personaggio che sembra cechoviano». Su Registrazione di eventi (1964) di Roberto Roversi
Authors: Toracca Tiziano
Published: December 2024

Il saggio si concentra su Registrazione di eventi (1964) di Roberto Roversi, ricostruendone la ricezione critica, incentrata soprattutto sul carattere sperimentale del romanzo, e ipotizzando una somiglianza di famiglia con altri romanzi italiani degli anni Sessanta e Settanta alla luce della categoria di neomodernismo. In questa prospettiva, a partire dal confronto con una novella di Čechov (Il conoscente) e da una riflessione su alcune opposizioni chiave del testo, vengono approfonditi i due grandi temi del romanzo, l’indigenza del protagonista e il suo rapporto traumatico col passato.
Essere “prima Campoformio”. Ipotesi indiziarie su Roversi e Fortini
Authors: Fichera Gabriele
Published: December 2024

Questo saggio si propone di esplorare alcuni versanti dei rapporti fra Roversi e Fortini, individuando in Dopo Campoformio l’opera su cui è possibile imbastire un dialogo fra i due autori. Il confronto parte da una premessa di tipo etico-ideologica, ovvero dal problema del ritardo con cui spesso gli uomini affrontano gli eventi storici decisivi che li riguardano, e quindi dall’idea espressa da un verso di Rebora per cui «vivere è giustificarsi». In un secondo momento l’analisi, ormai calata sulla concretezza dei testi, è tesa a verificare l’esistenza di un’estesa area lessicale comune, di matrice di nuovo reboriana, che lega le due esperienze poetiche, pur nella dialettica ineliminabile dell’essere prima e dell’essere “dopo Campoformio”.
«Ulisse coperto di sale». Roversi e Dalla
Authors: Marchionne Mario
Published: December 2024

L’articolo cerca di fare il punto su un aspetto poco studiato nell’attività di Roberto Roversi, ossia il sodalizio con Lucio Dalla. Fra il 1973 e il 1976 i due artisti hanno realizzato tre album importanti nell’ambito della canzone italiana. Il contributo evidenzia i più significativi momenti, sia dal punto di vista della costruzione delle canzoni, sia delle scelte contenutistiche. Centrale è l’attenzione relativa al problema della comunicazione, del pubblico, del senso finale di questa operazione “ardita”, e cioè scrivere canzoni in cui musica e testo si combinino paritariamente: né la musica, né il testo fungono da accompagnamento. Nei tre album emergono diverse realtà volte a disegnare alcuni momenti della nostra storia e quotidianità, con un’attenzione quasi di carattere antropologico, in grado di scavare nel profondo, esaltando le doti canore e musicali di Lucio Dalla.
Segni, ferite, animali e figure: su Libri e contro il tarlo inimico di Roberto Roversi (2012)
Authors: Portesine Chiara
Published: December 2024

Il contributo si propone di attraversare criticamente Libri e contro il tarlo inimico (2012), una raccolta di settanta poesie dedicate al tema della lettura e delle biblioteche (private e pubbliche). In primo luogo, verranno isolati e commentati i casi di “animalizzazione” dell’oggetto-libro, spesso paragonato da Roversi ad animali domestici e selvatici. Oltre a questi bestiari metaforici, l’analisi si concentra sull’apparato iconografico, con un approfondimento specifico su Tre invettive contro il tarlo, nemico del libro, un libro d’artista pubblicato nel 1997 con tre poesie di Roversi e un’incisione di Romano Masoni.
Notizia e testo di una traduzione dispersa di Roberto Roversi, con un’analisi metrica e una postilla
Authors: Zucco Rodolfo
Published: December 2024

L’antologia di Poeti latini tradotti da scrittori italiani contiene quattro brani delle Georgiche tradotti da Roberto Roversi. Il traduttore impiega prevalentemente un verso lungo la cui analisi porta a raggruppare quattro varianti esametriche. Nella prospettiva che considera i versi accentuativamente, l’esametricità è costituita dai sei ictus. La presenza di versi su sei ictus è in effetti significativa. L’esametricità di queste Georgiche è dunque garantita, oltre che dalla clausola, da un lato dalla loro continuità con l’esametro nelle forme delle Odi barbare, dall’altro dal loro profilo accentuale. Da qui l’ipotesi che il computo degli ictus possa essere utile anche nella valutazione della metricità del verso lungo di Roversi poeta in proprio.
La solidarietà degli opposti. Roberto Roversi e Vittorio Sereni
Authors: Daino Luca
Published: December 2024

Il saggio propone un’indagine intorno al rapporto tra Roberto Roversi e Vittorio Sereni. Si prendono dapprima in considerazione le loro relazioni intellettuali (le collaborazioni alle riviste da loro dirette: «Rendiconti» e «Questo e altro», ma anche «Paragone») e editoriali: Sereni, in quanto direttore letterario della Mondadori, ha trattato a lungo, ma senza successo, l’approdo di Roversi all’editore milanese. Vengono poi passate al vaglio le loro idee circa la funzione dello scrittore e della letteratura, nonché le rispettive strategie espressive. Emerge un quadro nel quale la reciproca stima personale e letteraria non impedisce di misurare le profonde differenze fra questi due scrittori, che si collocano agli antipodi del mondo culturale progressista del secondo Novecento italiano.
Sul carteggio Roversi-Fortini (1957-1993)
Authors: Vuozzo Alessandro
Published: December 2024

L’articolo offre una panoramica generale del carteggio inedito tra Roberto Roversi e Franco Fortini, conservato in parte presso l’Archivio Franco Fortini della Biblioteca Umanistica dell’Università di Siena, in parte presso l’Archivio privato di Antonio Bagnoli a Bologna. Attraverso una selezione di lettere vengono esplorati temi ed episodi centrali dello scambio epistolare, dalla comune partecipazione alla redazione di «Officina» fino alle tensioni politiche che portarono verso la fine degli anni Settanta alla definitiva rottura tra i due intellettuali. All’analisi dei singoli documenti è affiancata una ricostruzione essenziale del contesto culturale al cui interno si sviluppò il dialogo tra due dei protagonisti della storia letteraria e critico-militante del secondo Novecento.
«Squinternati e crassosi romanzi»: per un’indagine su Gadda lettore di Céline
Authors: Basile Francesco
Published: December 2024

Il saggio propone quindi un’analisi comparata tra due loci testuali provenienti da La cognizione del dolore e da Voyage au bout de la nuit per mettere in luce la possibile presenza del Voyage tra le molteplici fonti cui Gadda attinse durante la stesura della Cognizione. La prima parte del saggio presenta un raffronto tematico tra i due brani per suggerire che il segmento della Cognizione potrebbe essere stato ispirato dalla lettura del passo céliniano. Successivamente, lo scritto si focalizza su alcuni aspetti linguistici dei due estratti, formulando l’ipotesi che una neoformazione presente nel testo gaddiano potrebbe essere considerata un calco linguistico proveniente dal francese e, nello specifico, dal romanzo céliniano.
Lo scrittore e lo storico. Percorsi di una lettera di Italo Calvino a Delio Cantimori sul Barone rampante
Authors: Parodi Jacopo
Published: December 2024

Partendo da una lettera di Italo Calvino a Delio Cantimori, questo contributo si propone di leggere il rapporto tra verità storica e verità romanzesca, cercando di comprendere il filo che intercorre tra il Barone rampante e la storiografia cantimoriana, in particolare quella che si concentra sui giacobini italiani. Che cosa vuole dire che il romanzo di Calvino intrattiene con le pagine degli Utopisti di Cantimori uno stretto legame? In altri termini, il Barone Cosimo è nato dalla lettura di una storiografia particolare, dal respiro narrativo, come quella di Delio Cantimori o, per fare un altro esempio, di Franco Venturi? Qual è il sentimento della storia e della storia come tragedia che abita e permea un romanzo fantastico come quello di Calvino?
Spigolature stenbeckiane
Authors: Moscadelli Stefano
Published: December 2024

Nel contesto dell’attenzione ricevuta dalle opere di Steinbeck tra la fine degli anni Trenta e i primi anni Quaranta, spicca quella verso The Moon is down/Nuits sans lune. Fatto circolare già in una edizione londinese (1944) prima della sua diffusione col titolo La luna è tramontata, il testo fortemente impegnato nel sostenere la guerra partigiana ricevette ben presto in Italia una riduzione teatrale, ampiamente commentata all’indomani della guerra con grandi elogi dalla critica del tempo. Il successo di Steinbeck in Italia continuò nel corso degli anni Cinquanta, quando lo scrittore fu più volte in Italia. Di questi viaggi restano tracce negli archivi, specie di quello della primavera 1957 quando Steinbeck, soggiornando a Firenze, incontrò tra gli altri Bernard Berenson, al quale inviò poi una lettera di gratitudine per l’ospitalità ricevuta, qui per la prima volta integralmente pubblicata e contestualizzata.
Scrivere e risignificare. Tre percorsi dal dramma incompiuto Andrea e il Presidente a Foglio di via e altri versi di Franco Fortini
Authors: Romano Jacopo Maria
Published: December 2024

L’articolo analizza la tragedia incompiuta di Franco Fortini Andrea e il Presidente (1943-1945 circa) e ne esamina l’evoluzione progettuale tramite uno studio dei testimoni conservati nell’Archivio Franco Fortini. Si dimostra come il dramma, anche se abbandonato dall’autore, possieda un complesso rapporto con la raccolta d’esordio Foglio di via e altri versi (1946), a partire dalla presenza degli avantesti delle liriche Coro dell’ultimo atto, Sonetto e Varsavia 1944. Sono esaminate le evoluzioni che i testi hanno dalle diverse redazioni del dramma fino al loro inserimento in Foglio di via, privilegiando in particolar modo le modifiche formali, le conseguenze della variazione del soggetto di enunciato e le aggiunte paratestuali.