bluuebunny/crossref_metadata_2025 huggingface dataset:
Use of a new set of key performance indicators for evaluating the performance of an in vitro fertilization laboratory in which blastocyst culture and the freeze-all strategy are the primary treatment in patients with in vitro fertilization
Authors: Wang Hui-tian , Hong Ping-ping , Li Hai-yang , Zhou Wen , Li Tao
Published: September 2021

Objective

To evaluate the performance of an in vitro fertilization (IVF) laboratory using a new set of key performance indicators (KPIs) when the main treatment of IVF patients had been changed.

Methods

Patients who underwent fresh embryo transfer and the freeze-all strategy in August, September, and October 2017 were retrospectively studied to evaluate the performance of an IVF laboratory in September when implantation rate of fresh embryo transfer decreased. KPIs associated with blastocyst culture and the first frozen embryo transfer (FET) cycle in patients with the freeze-all strategy were compared over 3 months.

Results

Day 5 usable blastocyst and good quality blastocyst rates, and day 3 usable/good quality embryo rates were not different among the three periods. The implantation rate and KPIs associated with morphological changes in warmed blastocysts in the first FET cycle in patients with the freeze-all strategy were also not different among the periods.

Conclusions

KPIs associated with embryo quality, blastocyst culture, and the pregnancy outcome of the first FET cycle in patients with the freeze-all strategy suggested that performance was unaffected in our IVF laboratory in September. These KPIs might be useful for internal quality control analysis of IVF laboratories.
Tuberculosis screening coverage and isoniazid preventive therapy among people living with HIV at Gambella Hospital, southwest Ethiopia: a retrospective study design
Authors: Aboma Mecha , Dida Nagasa
Published: September 2021

Objective

We aimed to assess the coverage of tuberculosis screening and isoniazid preventive therapy (IPT) among people living with human immunodeficiency virus (PLHIV) at Gambella Hospital, southwest Ethiopia.

Methods

We conducted a 5-year retrospective study of PLHIV receiving care in an antiretroviral therapy clinic from 1 January 2011 to 30 December 2015. We reviewed a total of 900 medical records of patients with complete information.

Result

Of the total, 897 (99.7%) PLHIV were screened for tuberculosis, among which 77 (8.6%) were found to be positive for active tuberculosis. Among 820 (91.4%) individuals eligible for IPT, only 545 (66.5%) were provided IPT; 275 (33.5%) eligible PLHIV were not provided IPT. Male sex (adjusted odds ratio [AOR] 1.63) and ages 18–29 years (AOR 0.33) and 30–44 years (AOR 0.31) were significantly associated with the likelihood of tuberculosis infection.

Conclusion

The present study findings demonstrated that tuberculosis screening for PLHIV at Gambella Hospital was improved in comparison with reports from many African countries and other parts of Ethiopia. Despite this improvement, the implementation rate of IPT was below national and World Health Organization recommendations. Overall, tuberculosis diagnostic approaches and available preventive measures should be strengthened in the study area.
Charles and Emma Darwin: Under the ‘influence’ of chloroform anaesthesia
Authors: Paull John D , Cooper Michael G
Published: September 2021

A number of Charles Darwin’s biographies record the administration of chloroform by Darwin to his wife Emma, during her labour and delivery of her eighth child, Leonard. This occurred on 15 January 1850, a little over two years after James Young Simpson in Edinburgh described the analgesic action of inhaled chloroform. An online search of more than 9000 items of Darwin’s correspondence at Cambridge University and other sources revealed that he was an active proponent and user of chloroform in midwifery, for euthanising animals he studied, as well as in botanical studies of carnivorous plants. He also discovered that the concurrent inhalation of chloroform, during its administration to his wife, alleviated his distressing anxiety which he suffered when present at her earlier confinements.
Doron medicum—the gift of medicine: How a rare 17th century medical translation positively impacted the community and predicted current analgesic techniques
Authors: Apelbaum Natalie
Published: September 2021

In 1683, a self-proclaimed apothecary physician and London professor of physick by the name of Guilelmus (William) Salmon authored a pharmacopoeia titled Doron medicum, the ‘gift of medicine’ (Greek/Latin translation). This text formulates an English supplement to the Latin Materia medica (16th century), discussing internal and external compound medicines of the late 17th century. This pharmacopoeia enabled those incapable of reading Latin to provide medical care to a challenging post-plague community. Opiology, mercury, dragon’s blood, willow bark, animal preparations and therapies now considered obscure, provide insight into therapies at the time. Early critical care treatments in haemorrhage control and pain management are described.

Doron medicum preceded the controversial opening by the College of Physicians of the first London Dispensary in 1698, and was published in a maturing period of medical governance and healthcare establishment in London. During the 17th century, great competition and debate existed between the Royal College of Physicians and the apothecaries. Throughout such debates, William Salmon advocated for access to medical care for the poor and recognition of an allied approach to healthcare.

This paper discusses Salmon’s contribution to medicine, which has been poorly transcribed in medical history. A selection of opiate-based analgesic therapies, early critical care strategies and animal preparations are revisited. A small chronicle of William Salmon’s life and professional achievements will be reviewed. Debate surrounding the opening of the first London Dispensary will be discussed in relation to William Salmon’s contribution, echoing ongoing contemporary challenges in healthcare over 300 years later.
Preservation storage in a flood damage mitigation effort at the National Library of France
Authors: Allain Céline , Guérinot Sophie
Published: September 2021

During a flood alert, the decision to evacuate a threatened collection of a library is an important one. If not thought out carefully, a hastily executed move can expose valuable collections to unforeseen threats. Although floods are usually slow to develop in Paris, the decision to make a preventive evacuation must be taken at the appropriate moment, considering the time needed for the relocation, the reality of the threat and the need for service continuity. In the context of its flood protection plan, the National Library of France has conceived a box model that contributes to saving time in case of a flood and prevents damage during an evacuation. Combining accessibility to documents with security requirements, this model can be implemented in different contexts.
Predicting Grocery Store Visits During the Early Outbreak of COVID-19 with Machine Learning
Authors: Bian Ruijie , Murray-Tuite Pamela , Wolshon Brian
Published: September 2021

While non-essential travel was canceled during the coronavirus infectious disease (COVID-19) pandemic, grocery shopping was essential. The objectives of this study were to: 1) examine how grocery store visits changed during the early outbreak of COVID-19, and 2) estimate a model to predict the change of grocery store visits in the future, within the same phase of the pandemic. The study period (February 15–May 31, 2020) covered the outbreak and phase-one re-opening. Six counties/states in the United States were examined. Grocery store visits (in-store or curbside pickup) increased over 20% when the national emergency was declared on March 13 and then decreased below the baseline within a week. Grocery store visits on weekends were affected more significantly than those on workdays before late April. Grocery store visits in some states (including California, Louisiana, New York, and Texas) started returning to normal by the end of May, but that was not the case for some of the counties (including those with the cities of Los Angeles and New Orleans). With data from Google Mobility Reports, this study used a long short-term memory network to predict the change of grocery store visits from the baseline in the future. The networks trained with the national data or the county data performed well in predicting the general trend of each county. The results from this study could help understand mobility patterns of grocery store visits during the pandemic and predict the process of returning to normal.
Relating Field Moduli of Asphalt Mixture Layer Under Vehicular Loading and its Dynamic Moduli Under Laboratory Loading
Authors: Cheng Huailei , Sun Lijun , Yang Ruikang , Zhang Yining , Liu Liping
Published: September 2021

The modulus of the asphalt layer is an essential input parameter in asphalt pavement design. For design purposes, the relationship between field and laboratory moduli of the asphalt mixture layer needs to be identified. In this research, the field modulus of the asphalt layer is predicted via a developed field modulus master curve. The laboratory modulus of asphalt mixture is measured using three different loading modes, namely uniaxial compressive (UC), indirect tensile (IDT), and four-point bending (4PB) modes. The loading mode is observed to affect the mixture’s laboratory modulus. The asphalt mixture moduli measured from UC mode are generally the highest, following by those from IDT mode, whereas the 4PB mode generates the lowest asphalt mixture moduli. By comparing field and laboratory moduli of asphalt mixture, it is found that the laboratory modulus from 4PB mode yields satisfactory predictions for the mixture’s field modulus in a wide range of loading frequencies. The UC and IDT modes, which tend to overpredict the field modulus of the asphalt layer, need to be modified. The modification factor ranges between 0.3 and 0.7 for UC mode, and varies from 0.2 to 1.0 for IDT mode. For both modes, the modification factors grow closer to 1.0 with increasing frequencies and decreasing temperatures, implying that UC and IDT modes become increasingly suitable for simulating field conditions at high frequencies and low temperatures.
Conditional Transit Signal Priority for Connected Transit Vehicles
Authors: Cvijovic Zorica , Zlatkovic Milan , Stevanovic Aleksandar , Song Yu
Published: September 2021

Connected vehicle (CV) technologies enable safe and interoperable wireless communication among vehicles and the infrastructure with the possibility to run many applications that can improve safety, and enhance mobility. This paper develops CV-based algorithms which use transit vehicle speed and the estimated time that the vehicle needs to arrive at an intersection to trigger transit signal priority (TSP) initiation. This information is updated each second based on the traffic conditions such as speed, a current distance of a transit vehicle to the intersection, and queue conditions. The algorithm uses the actual speed of a transit vehicle and its latitude/longitude (lat/lon) coordinates to compute the time that the vehicle needs to reach the stop line. It was tested on a real-world network using VISSIM traffic simulation, but can easily be implemented in the field, since it is using world coordinates. The upgraded algorithm was applied to a future bus rapid transit (BRT) scenario, and included different levels of conditional TSP, which depend on three combined conditions: the time that a transit vehicle needs to reach the stop line, the number of passengers on board, and the lateness that the transit vehicle experiences. The test-case network used for model building is a corridor consisting of ten signalized intersections along State Street in Salt Lake City, UT. The CV algorithms coupled with TSP can yield notable delay reductions for both the regular bus and the BRT of 33% and 12%, respectively.
Does Displaying Safety Messages on Dynamic Message Signs have Measurable Impacts on Crash Risk?
Authors: Megat-Johari Megat-Usamah , Megat-Johari Nusayba , Savolainen Peter T. , Gates Timothy J. , Kassens-Noor Eva
Published: September 2021

Transportation agencies have increasingly been using dynamic message signs (DMS) to communicate safety messages in an effort to both increase awareness of important safety issues and to influence driver behavior. Despite their widespread use, evaluations as to potential impacts on driver behavior, and the resultant impacts on traffic crashes, have been very limited. This study addresses this gap in the extant literature and assesses the relationship between traffic crashes and the frequency with which various types of safety messages are displayed. Safety message data were collected from a total of 202 DMS on freeways across the state of Michigan between 2014 and 2018. These data were integrated with traffic volume, roadway geometry, and crash data for segments that were located downstream of each DMS. A series of random parameters negative binomial models were estimated to examine total, speeding-related, and nighttime crashes based on historical messaging data while controlling for other site-specific factors. The results did not show any significant differences with respect to total crashes. Marginal declines in nighttime crashes were observed at locations with more frequent messages related to impaired driving, though these differences were also not statistically significant. Finally, speeding-related crashes were significantly less frequent near DMS that showed higher numbers of messages related to speeding or tailgating. Important issues are highlighted with respect to methodological concerns that arise in the analysis of such data. Field research is warranted to investigate potential impacts on driving behavior at the level of individual drivers.
Safety Performance of Rural Curved Corner Intersections with Regional Effects
Authors: Ingle Anthony , Gates Timothy J.
Published: September 2021

This study evaluates the intersection of rural roads where a curved roadway segment connects the major flow of through traffic from orthogonal directions. A system of up to three intersections in combination can be represented singly by the situation modeled in this paper as a curved corner intersection site. This paper evaluates the application of random intercept negative binomial (NB) regression modeling to produce safety performance functions, and compares the outcome with NB models using fixed regional effects. At curved corner intersections, installing a combined/merged intersection approach near the midpoint of the curve is a potential countermeasure that by comparison with three-leg configurations experienced 20% fewer intersection crashes. A larger radius of curvature along the curved segment at these types of intersections is also very favorable for safety performance. Each 100 ft increase in the radius of a three-leg or four-leg curved corner intersection is estimated to reduce total non-animal crash occurrence by 5% and 7%, respectively. This study can help safety engineers to prioritize the improvement of rural un-signalized intersections.
Shoulder External Rotational Properties During Physical Examination Are Associated With Injury That Requires Surgery and Shoulder Joint Loading During Baseball Pitching
Authors: Stokes Hannah , Eaton Koco , Zheng Naiquan (Nigel)
Published: September 2021

Background:

Throwing arm injuries are common because of the demand on the shoulder. The shoulder is qualitatively checked regularly by team physicians. Excessive instability and joint loading in baseball pitching are risk factors for throwing arm injuries. Knowledge of shoulder flexibility, range of motion, and joint loading may provide new insights for treatments to reduce the likelihood of injury incidence.

Purpose:

To investigate the relationship among injuries, shoulder external rotational properties, and shoulder joint loading in baseball pitchers.

Study Design:

Descriptive laboratory study.

Methods:

Pitching kinetics, shoulder rotational tests, and self-reported injury questionnaires were used to study 177 collegiate baseball pitchers. Pitching motion data were collected at 240 Hz using a motion capture system. A custom program calculated the shoulder joint loading. The shoulder rotational test quantitatively records shoulder range of motion and flexibility using a custom-made wireless device. Self-reported injury questionnaires were filled out during tests and yearly follow-ups. The total length of the study was 5 years. Analysis of variance, chi-square, and regression tests were performed to compare differences among groups and detect correlations with surgery and shoulder joint loadings.

Results:

There were significant differences in shoulder flexibility among surgery groups. Shoulder external rotational properties during physical examination were significantly associated with shoulder joint loading in baseball pitching. High shoulder external rotation was associated with 14% to 36% lower shoulder posterior force and adduction, internal rotation, and horizontal adduction torque ( P < .05). High shoulder flexibility was associated with 13% higher anterior force ( P < .05). High shoulder external rotation before external rotation torque was applied was associated with 13% to 33% lower shoulder inferior force and adduction, internal rotation, and horizontal adduction torque ( P < .05). There were no significant differences in shoulder joint loading among the surgery groups.

Conclusion:

Shoulder injuries that require surgery were associated with shoulder external rotation flexibility. High shoulder external rotation may be advantageous because it lowers the force and torque on the shoulder joint.

Clinical Relevance:

The ability to understand shoulder external rotational properties, joint loading, and injury during baseball pitching helps further our understanding of injury mechanisms. The shoulder rotational test should be used as a screening tool to identify players at risk.
Neo-Dualism: Accumulation, Distress, and Proliferation of a Fissured Informality
Authors: Sadhu Kasturi , Chakrabarti Saumya
Published: September 2021

A dominant strand of orthodoxy argues that the problem of the informal sector could be mitigated through the capitalistic growth process. But our observations on India are different—with an expansion of the capitalistic formal sector, as the economy grows, there is a proliferation of fissured informality. Using a structuralist macro-model, we provide certain explanations for this phenomenon, which are also tested empirically using Indian subnational-state and firm-level data. Thus, we explore both the short- and long-run effects of the expansion of the formal sector on the heterogeneous informal economy. While a section of the population is pulled into the advanced informal activities, a vast segment is pushed to petty production. Accordingly, the orthodox transition narrative is questioned and alternative policy and political possibilities are introduced.

JEL Classification: O11, O13, O17, P48
Forms of Group Involvement: Alternatives to the Standard Question
Authors: Fischer Claude , Durham Xavier
Published: September 2021

Deciding whether Americans have become decreasingly involved in group life entails a methodological issue: Does the standard question about the associations to which respondents belong, asked for decades by the General Social Survey (GSS) and many others, miss newer and more diverse forms of group involvement? Following on Paxton and Rap, we mine a recent panel survey, UCNets, that provides several different means for allowing respondents to describe their group involvement. We observe more and much more varied kinds of group involvement than those elicited by the last GSS administration of the standard question in 2004. (Analyses in the Supplement of a few additional surveys confirm this diversity.) These results lead to suggestions for how to better measure involvement in groups, in particular being more sensitive to many axes of difference in the general population. The results have implications for the larger debate as well.
Domain Knowledge and Adaptive Serious Games: Exploring the Relationship of Learner Ability and Affect Adaptability
Authors: Verma Vipin , Craig Scotty D. , Levy Roy , Bansal Ajay , Amresh Ashish
Published: September 2021

Detection and responding to a player’s affect are important for serious games. A method for this purpose was tested within Chem-o-crypt, a game that teaches chemical equation balancing. The game automatically detects boredom, flow, and frustration using the Affdex SDK from Affectiva. The sensed affective state is then used to adapt the game play in an attempt to engage the player in the game. A randomized controlled experiment incorporating a Dynamic Bayesian Network that compared results from groups with the affect-sensitive states vs those without revealed that measuring affect and adapting the game improved learning for low domain-knowledge participants.
Diazinon exposure reduces bone mineral density in adult and immature rats: A histomorphometric and radiographic study
Authors: Bazmi Mahdiye , Elahifar Mahbubeh , Lari Roya , Shahri Naser Mahdavi
Published: September 2021

Diazinon has been widely used as a domestic and agricultural pesticide. This study examined the effects of diazinon on bone mineral density (BMD) of mature and immature rats. For this purpose, 24 adult Wistar rats (male; 8 weeks old) were initially divided into four groups ( n = 6). Corn oil was used as the control while diazinon at 15, 30, and 45 mg/kg in corn oil was given to mature rats via gavage per day. Since these dosages were lethal for the immature rats, 12 immature Wistar rats (male; 4 weeks old) ( n = 6) were gavaged with corn oil as control and 5 mg/kg of diazinon in corn oil. The animals were sacrificed on day 28 with their left femur bones removed for histomorphometric studies. BMD was measured in the right femur, using standardized radiographs in the femoral head, femoral neck, greater trochanter, and shaft. The Image J Program was used for measuring the bone lamellae and epiphyseal growth plates. The results of this study for the first time revealed that diazinon reduced BMD in both adults and immature rats. Diazinon exposure was associated with diminished trabecular and cortical bone density. Correspondingly, our results indicated that in immature rats, DZN led to the reduction in the epiphyseal growth plate width, both in the proliferation and hypertrophic zones. These results suggested that diazinon might be associated with impaired bone longitudinal growth as well as bone metabolism in adults.
Design and kinematic modeling of an origami-inspired cable-driven flexible arm
Authors: Liu Jiali , Xu Yong , Shi Haorang , Yang Jie
Published: September 2021

The cable-driven flexible arm based on the principle of origami is a new type of non-articulated compliant actuator with high integration, high environmental adaptability, large workspace/large deployment ratio. The forward/reverse kinematic models of joint space, operation space and driving space along with trajectory error model of the cable-driven flexible arm were proposed in this paper. The prototype of the flexible arm was developed capable of realizing bending, torsion and expansion/contraction. The simulation and experiment results of the cable-driven foldable flexible arm verified feasibility of the kinematic models and driving method proposed in this paper. Above research achievements lay necessary foundation for the next step to realize the key service functions of grasping/manipulation, three-dimensional precise movement, non-structural environment interaction/adaptation of the flexible arm with variable stiffness, variable configuration and variable size.
Electroacupuncture attenuates vascular hyporeactivity in a rat model of portal hypertension induced by bile duct ligation
Authors: Chen Yu-Sheng , Wen Chorng-Kai , Liu Geng-Hao , Lee Tzung-Yan
Published: September 2021

Background:

A hyperdynamic circulation and impaired vascular responsiveness to vasoconstrictors are observed in portal hypertension (PHT) rats. Inflammation is a major contributor to the hyperdynamic circulation state in murine models of PHT. Electroacupuncture (EA) may ameliorate the inflammatory response and limit arterial vasodilatation and portal pressure. This study investigated the possible mechanisms underlying putative hemodynamics effects of EA in normal and PHT rats.

Methods:

PHT was induced by bile duct ligation (BDL) surgery over 4 weeks in rats. Sham-operated and BDL rats were treated with low-frequency EA (2 Hz) at ST36 10 min three times weekly for one or two consecutive weeks (for a total of 3 or 7 treatments, respectively). Serum tumor necrosis factor-α (TNF-α), nitrite/nitrate (NOx) and 6-keto-prostaglandin F1α (6-keto-PGF1α) were analyzed, and hemodynamic variation and contractile responses to phorbol-12,13-dibutyrate and phenylephrine in aortic and superior mesenteric arterial rings were recorded. Inducible (i) and endothelial (3) nitric oxide synthase (NOS), cyclooxygenase-1 (COX-1), and protein kinase C-α (PKC-α) levels were determined by Western blotting.

Results:

EA significantly reduced portal pressure and serum TNF-α, NOx and 6-keto-PGF1α levels compared to the untreated BDL group, enhanced maximum contractile responses in the aorta, up-regulated PKC-α, and down-regulated iNOS and COX-1 levels. In addition, EA decreased the aortic angiogenesis signaling cascade, reflected by down-regulation of vascular endothelial growth factor (VEGF) abundance and transforming growth factor β receptor (TGFβR)I/II expression, as assessed by immunostaining.

Conclusion:

EA attenuates TNF-α, NO and 6-keto-PGF1α overproduction, modulates the vascular levels of constitutive NOS and PKC-α, blunts the development of the angiogenesis cascade, and enhances vascular contractile force in PHT rats.
Analysis and comparison of pain pressure threshold and active cervical range of motion after superficial and deep dry needling techniques of the upper trapezius muscle
Authors: Montero Navarro Sergio , del Rio Medina Sonia , Martín Botella Rico José , Isabel Rocha Ortiz María , Teresa Pérez Gracia María
Published: September 2021

Objectives:

To evaluate the changes in pain pressure threshold (PPT) and active cervical range of motion (ACROM) after the application of superficial dry needling (DN) or deep DN in myofascial trigger point (MTrP) 1 of the upper trapezius versus a simulated DN technique in the gastrocnemius muscle (control group).

Design:

Double-blind, randomized controlled trial with 7-day follow-up.

Participants:

Asymptomatic volunteers (n = 180; 76 men, 104 women) with a latent MTrP 1 in the upper trapezius were randomly divided into three groups: G1, receiving superficial DN in the upper trapezius; G2, receiving deep DN in the upper trapezius; and G3, control group, receiving simulated DN technique in the gastrocnemius muscle.

Main outcome measures:

While sitting in a chair, each subject underwent measurements of PPT and ACROM (ipsilateral and contralateral side flexion and rotation, flexion and extension) preintervention, (immediately) postintervention, and at 24 h, 72 h and 7 days.

Results:

Superficial and deep DN produced an increase in PPT at 7 days with respect to preintervention levels. Furthermore, superficial and deep DN produced a decrease in cervical flexion at 24 h and an increase in ipsilateral rotation until 72 h, increasing to 7 days in the case of deep DN. On the contrary, superficial DN produced an increase in ipsilateral and contralateral side flexion after intervention, unlike deep DN that produced a decrease at 24 h. Furthermore, superficial DN produced an increase in contralateral rotation at 24 h and deep DN decreased extension at 72 h.

Conclusion:

A single intervention of superficial or deep DN did not produce statistically significant changes in PPT or goniometry measurements. Trial registration number: NCT03719352 ( ClinicalTrials.gov )
The benefits of being a multi-capital: The economic impact of the international and European institutions and interest groups
Authors: Dotti Nicola Francesco , Spithoven André , Ysebaert Walter
Published: September 2021

Brussels is known worldwide for hosting (most of) the European institutions as well as several other international organisations like North Atlantic Treaty Organization (NATO). Besides the symbolic political value, their presence has an economic impact because of their administrative activities and staff remunerations. Estimating the economic impact poses two main challenges. First, the supranational nature of these organisations makes it challenging to quantify the size of these institutions and related bodies because country-based statistical systems hardly account for transnational organisations. Second, as these institutions and organisations mainly rely on taxpayers’ funding, policymakers need transparent estimates to assess the implications of their decisions as well as for a matter of accountability. For these purposes, a meticulous data collection is carried out, and transparent assumptions are used to estimate the local economic multiplier effect of these activities accounting for operational expenditures, employees’ consumption as well as (Belgian) taxes and saving. The results show that the economic impact for the Brussels-Capital Region lies between 23% and 26% of regional turnover and 19% and 20% of employment, while interregional spillovers are estimated being around 1.5% to 1.7% of regional turnover and 0.6% to 0.7% of employment for both Flemish and Walloon regions.
From the post-industrial prophecy to the de-industrial nightmare: Stagnation, the manufacturing fetish and the limits of capitalist wealth
Authors: Moraitis Alexis
Published: September 2021

The post-2008 era saw a return of the manufacturing fetish, the idea that manufacturing constitutes the flywheel of growth without which no nation can thrive. Across the Global North and South, voices are calling to reverse deindustrialization and revive manufacturing. While today deindustrialization is met with anxiety, in the 1930s economists predicted deindustrialization but interpreted it as a liberating process leading to a post-industrial age based on material abundance and widespread economic security. Far from delivering this vision, deindustrialization actually produces a precarious economic order driven by labour precarity, economic stagnation and lost development opportunities for the Global South. What can be termed the Baumolian and Kaldorian frameworks, attribute this precarious reality to services’ inability to replace manufacturing as a growth engine given their technologically stagnant nature. However, this article argues that, by focusing on the technical aspects of service economies, such views overlook the social limits of the capitalist economy and its historically specific conception of wealth, value. As capitalism matures, productivity becomes an increasingly inadequate form of augmenting social wealth as it results in great increases in physical output but counterintuitively undermines the expansion of value. Capitalism is underpinned by a secular movement towards declining dynamism, as it increasingly struggles to maintain its former economic vigour. Stagnation and heightened labour precarity are not merely the product of tertiarization but symptoms of capitalism’s declining trajectory.
Fecal PCR testing for detection of Clostridium perfringens and Clostridioides difficile toxin genes and other pathogens in foals with diarrhea: 28 cases
Authors: Magdesian K. Gary , Barnum Samantha , Pusterla Nicola
Published: September 2021

Clostridium perfringens and Clostridioides difficile cause significant morbidity and mortality in foals. Antemortem diagnosis of C. perfringens infection has been complicated by a paucity of tests available for toxin detection. Fecal PCR panels have assays for a variety of C. perfringens toxin gene sequences as well as for several other foal gastrointestinal pathogens. We evaluated results of a comprehensive fecal diarrhea PCR panel in 28 foals that had been presented to a referral hospital because of diarrhea. Sixteen (57%) foals were positive for C. perfringens and/or C. difficile toxin gene sequences on fecal PCR, including 3 foals positive for NetF toxin. These foals were younger ( p = 0.0029) and had higher hematocrits ( p = 0.0087), hemoglobin ( p = 0.0067), and red blood cell concentrations ( p = 0.028) than foals with diarrhea that tested negative for clostridial toxins. The foals had lower total protein concentrations ( p = 0.045) and were more likely to have band neutrophils on a CBC ( p = 0.013; OR: 16.2). All 3 foals with NetF toxin gene sequences detected in feces survived to discharge, indicating that diarrhea caused by NetF toxigenic C. perfringens isolates is not uniformly fatal.
Development of Patient Education Material for Proton Pump Inhibitor Deprescribing: A Mixed-Methods Study
Authors: Nguyen-Soenen Jérôme , Jourdain Maud , Fournier Jean-Pascal
Published: September 2021

Background:

Proton pump inhibitor (PPI) deprescribing is recommended in case of inappropriate use. Patient education materials are key elements in the deprescribing process.

Objective:

The study objective was to develop patient education material for PPI deprescribing in primary care in France.

Methods:

This was a mixed-methods study involving (1) a literature review of the existing patient education materials on PPI deprescribing to identify key points to optimize the layout and content of the document; (2) development of a first version of the brochure by a pluri-professional steering group, following the national reference methodology of the French National Authority for Health (Haute Autorité de Santé) and iterative modifications of the patient brochure; (3) assessment of the content and understandability of the brochure by questionnaires followed by semistructured interviews with target patients; and (4) iterative brochure readability assessment with the Flesch reading ease tool.

Results:

The final patient education material is a double-sided A3 brochure—that is, 4 A4 pages. The first round of user testing by questionnaire (n = 14 patients) led to modifications to improve the document understandability, validated in the second round of user testing by questionnaire (n = 10 patients). The semistructured interviews (n = 10 patients) highlighted an adequate comprehension, whereas actionability required some minor modifications. The readability test score of the final education brochure was 59.4.

Conclusion and Relevance:

This patient education brochure for PPI deprescribing is targeted to patients in primary care. Its impact on PPI deprescribing will be assessed in a population-based pragmatic trial in primary care.
Balancing Political and Criminogenic Needs: Evaluating the New Zealand Department of Corrections’ Response to Men Assessed With a Below Average Risk for Sexual Recidivism
Authors: Carr Angela E. , Willis Gwenda M.
Published: September 2021

Current research provides little evidence for the effectiveness of treatment in reducing sexual offence recidivism amongst low-risk populations. However, in real-world correctional settings, program delivery rarely occurs in a vacuum, treatment may be politically mandated and unidimensional measures of program success may preclude recognition of broader benefits. The current study investigated the effectiveness of a low-intensity treatment program, both in terms of participants’ recidivism outcomes and in terms of broader organizational/systems impacts. The results demonstrated low base rate recidivism across both program participants ( n = 311) and a comparison group of men who were assessed as demonstrating similar static sexual offence recidivism risk ( n = 391), and little evidence of reduced recidivism following treatment. However, program administration led to many potential participants being identified as demonstrating higher levels of dynamic risk and overridden to more intensive treatment options ( n = 101). Given evidence that such options do effectively reduce recidivism in higher risk populations, these findings may suggest an overall positive net effect.
Teledermatology Utilization and Integration in Residency Training Over the COVID-19 Pandemic
Authors: Mahmood Farhan , Cyr Janelle , Keely Erin , Afkham Amir , Guglani Sheena , Walker Jim , DesGroseilliers Jean-Pierre , Kirshen Carly
Published: September 2021

Background

During the 2019 Coronavirus (COVID-19) pandemic, the Division of Dermatology, University of Ottawa, adapted pre-existing local healthcare infrastructures to provide increased provider-to-provider teledermatology services as well as integrated teledermatology into the dermatology residency training program.

Objectives

(1) To assess the differences in utilization of provider-to-provider teledermatology services before and during the COVID-19 pandemic; and (2) to assess dermatology resident and faculty experiences with the integration of teledermatology into dermatology residency training at the University of Ottawa.

Methods

We conducted a cross-sectional analysis comparing provider-to-provider teledermatology consults submitted to dermatologists from April 2019 to October 2019 pre-pandemic with the same period during the pandemic in 2020. Two different questionnaires were also disseminated to the dermatology residents and faculty at our institution inquiring about their perspectives on teledermatology, education, and practice.

Results

The number of dermatologists completing consults, the number of providers submitting a case to Dermatology, and the number of consults initiated all increased during the pandemic period. Ninety-one percent of residents agreed that eConsults and teledermatology enhanced their residency education, enabled continuation of training during the pandemic, and that eConsult-based training should be incorporated into the curriculum. Ninety-six percent of staff incorporated a virtual dermatology practice model, and one-third used teledermatology with residents during the pandemic. Most staff felt there was value in providing virtual visits in some capacity during the pandemic.

Conclusions

Our study confirms that the use of teledermatology services continues to increase accessibility during the pandemic. Teledermatology enhances the education and training of residents and will be incorporated into dermatology residency programs.
Musical achievement during a lockdown: The parental support miracle
Authors: Oliveira António , McPherson Gary , Mota Ribeiro Luísa , Oliveira-Silva Patrícia
Published: September 2021

The quality of parental support is recognized as a crucial factor in the early stages of a student’s development, and particularly in instrumental music education. At the start of 2020, the outbreak of a global pandemic crisis posed new and unprecedented challenges to education, forcing families to stay at home to prevent contagion. This investigation was conducted during the period of a COVID pandemic lockdown in Portugal. We explored whether parental support, provided during the lockdown period, was associated with their child’s achievement as reported by their instrumental music teacher. For this study, 39 parent–teacher dyads of first-grade students of an instrument music course were recruited from two public music conservatories. Parents supplied information on the frequency in which they provided student-support-related attitudes and actions in the home context. Simultaneously, teachers provided information about the student’s achievement during the lockdown compared with the previous in-person performance period. Results indicate a strong relationship between parental support and musical achievement, with students who received higher levels of supportive parental involvement performing better than before the pandemic crisis. The findings are discussed in relation to the importance of parental involvement in a child’s instrumental music education.
Teaching multiple approaches to management to facilitate prosocial and environmental well-being
Authors: Dyck Bruno , Caza Arran
Published: September 2021

Friedman’s maxim “The social responsibility of business is to increase its profits” (p. 32) has shaped what managers consider effective management. This Financial Bottom Line approach to management has been challenged by both Positive Organizational Scholarship (POS) and Critical Management Studies (CMS). POS highlights how enhancing prosocial and other nonfinancial considerations can increase profits, consistent with the current dominant Triple Bottom Line approach. In contrast, CMS tends to critique any approach that seeks to maximize profits by creating dysfunctional power symmetries and marginalization. This study introduces a third option, the Social and Ecological Thought approach, which promotes maximizing social and ecological well-being while remaining financially viable. A longitudinal pre-post intervention in a sample of undergraduate management students showed that teaching multiple approaches to management—Financial Bottom Line, Triple Bottom Line, and Social and Ecological Thought—resulted in learners becoming less likely to espouse profit-related goals (e.g. to maximize efficiency, productivity, profitability) and more likely to identify nonfinancial ones (e.g. extra-organizational prosociality and reduction of marginalization) when characterizing effective management. However, the results did not support predictions regarding intra-organizational prosociality and marginalization, or power asymmetries. We discuss implications for pedagogy and the future development of POS and CMS.
Single mothers and resistance to welfare-to-work: A Bourdieusian account
Authors: Casey Simone
Published: September 2021

This research applied Bourdieusian field theory to explain the forms of resistance exercised by single mothers exposed to the cultural and economic domination of Australian welfare-to-work policy. The mothers were affected by policy changes that reduced their social security benefit income and brought them into the field of activation policies. Unlike other studies focusing on well-being effects, this study focused on understanding resistance, that is, how welfare subjects like single mothers exercise resistance in dominating contexts. Bourdieusian field theory was applied to explain these resistances as a reaction to a social policy reclassification and to identity the enabling resources for it. This article observes the conditions that enabled single mothers to convert individual forms of resistance into collective action. In this respect, Husu’s adaptation of Bourdieusian field theory to social movement studies provided insight into how dominating fields like those of activation policy, generate resistances and social movements.
Deplatformization and the governance of the platform ecosystem
Authors: Van Dijck José , de Winkel Tim , Schäfer Mirko Tobias
Published: September 2021

This article analyzes deplatformization as an implied governance strategy by major tech companies to detoxify the platform ecosystem of radical content while consolidating their power as designers, operators, and governors of that same ecosystem. Deplatformization is different from deplatforming: it entails a systemic effort to push back encroaching radical right-wing platforms to the fringes of the ecosystem by denying them the infrastructural services needed to function online. We identify several deplatformization strategies, using Gab as an example of a platform that survived its relegation and which subsequently tried to build an alternative at the edge of the mainstream ecosystem. Evaluating deplatformization in terms of governance, the question that arises is who is responsible for cleansing the ecosystem: corporations, states, civil society actors, or all three combined? Understanding the implied governance of deplatformization is imperative to assess the higher stakes in future debates concerning Internet governability.
Road to micro-celebration: The role of mutation strategy of micro-celebrity in digital media
Authors: Chen Xingyu , Jiang Ling , Miao Sentao , Shi Cong
Published: September 2021

The process of how ordinary people evolve to be well-known by delivering varied digital media content (i.e. micro-celebrification) remains perplexing. This study examines the role of mutation strategy featuring: (1) mutation diversity (the degree of evenness of content distribution across mutated styles) and (2) mutation divergence (i.e. the degree of inhomogeneity among mutated content styles), in predicting the success of micro-celebrification for ordinary people with varying talent levels. The results of survival analysis of a talent competition streamed on a major digital media platform in China suggest that a more diverse mutation in media content yields a higher chance of micro-celebrity success among participants in the competition. Interestingly, less talented participants benefit more from increasing mutation diversity compared with highly talented peers. Moreover, higher mutation divergence in the emotion evoked by media content increases the chance of success in micro-celebrification, opposite to that in the content genre and creator trait.
Saving as a Path for Female Empowerment and Entrepreneurship in Rural Peru
Authors: Daher Marianne , Rosati Antonia , Jaramillo Andrea
Published: September 2021

Much research has identified the difficulties of promoting women’s empowerment using microcredit, but there has been little research on the potential for empowerment from promoting women’s savings. We address this gap through a qualitative study of three women’s savings programmes in the Highlands of Peru. The results reveal changes in several domains of women’s lives (economic, personal and relational), emphasizing that these programmes enable them to think about the future, expand their social support networks, and become entrepreneurs. We conclude that savings interventions have considerable advantage over microcredit programmes for facilitating female empowerment and that the merits of these interventions go far beyond financial inclusion with significant impacts on women’s psychosocial well-being and broader empowerment.
An assessment of root stage of canine and premolar teeth at alveolar eruption
Authors: Corns Stephanie , Liversidge Helen , Fleming Padhraig S
Published: September 2021

Objective:

The primary aim was to evaluate the degree of root development of permanent canines at the time of alveolar eruption. We also aimed to assess whether differences in the degree of root development at alveolar eruption exist between permanent canines and premolars and between maxilla and mandible.

Design:

A cross-sectional study.

Setting:

Barts and The London School of Medicine and Dentistry, Queen Mary University of London.

Participants:

Two hundred dental panoramic radiographs taken as part of routine dental care.

Methods:

Radiographs were assessed for canine and premolar root development stage and eruption level with calibration and repeat measurements undertaken.

Results:

Two hundred and sixty teeth were identified as being at the level of alveolar eruption. The majority of maxillary canines reached alveolar eruption when root formation was complete. Most premolars and mandibular canines reached alveolar eruption when roots were three-quarters developed. At alveolar eruption, canines were statistically more mature than premolars (p<0.001) and maxillary teeth were more mature than mandibular teeth (p<0.05).

Conclusions:

Root development appears to be particularly advanced for maxillary permanent canines, being essentially root-complete at alveolar eruption, while premolars and mandibular permanent canines appear to have three-quarters root development at this stage. This information may be used to inform whether and when to extract primary teeth for orthodontic reasons.