bluuebunny/crossref_metadata_2025 huggingface dataset:
Metagenomic Analysis of the Respiratory Microbiome of a Broiler Flock from Hatching to Processing
Authors: Mulholland Kelly A. , Robinson Monique G. , Keeler Sharon J. , Johnson Timothy J. , Weber Bonnie W. , Keeler Calvin L.
Published: March 2021

Elucidating the complex microbial interactions in biological environments requires the identification and characterization of not only the bacterial component but also the eukaryotic viruses, bacteriophage, and fungi. In a proof of concept experiment, next generation sequencing approaches, accompanied by the development of novel computational and bioinformatics tools, were utilized to examine the evolution of the microbial ecology of the avian trachea during the growth of a healthy commercial broiler flock. The flock was sampled weekly, beginning at placement and concluding at 49 days, the day before processing. Metagenomic sequencing of DNA and RNA was utilized to examine the bacteria, virus, bacteriophage, and fungal components during flock growth. The utility of using a metagenomic approach to study the avian respiratory virome was confirmed by detecting the dysbiosis in the avian respiratory virome of broiler chickens diagnosed with infection with infectious laryngotracheitis virus. This study provides the first comprehensive analysis of the ecology of the avian respiratory microbiome and demonstrates the feasibility for the use of this approach in future investigations of avian respiratory diseases.
Changes in Gut Microbiota after a Four-Week Intervention with Vegan vs. Meat-Rich Diets in Healthy Participants: A Randomized Controlled Trial
Authors: Kohnert Eva , Kreutz Clemens , Binder Nadine , Hannibal Luciana , Gorkiewicz Gregor , Müller Alexander , Storz Maximilian Andreas , Huber Roman , Lederer Ann-Kathrin
Published: March 2021

An essential role of the gut microbiota in health and disease is strongly suggested by recent research. The composition of the gut microbiota is modified by multiple internal and external factors, such as diet. A vegan diet is known to show beneficial health effects, yet the role of the gut microbiota is unclear. Within a 4-week, monocentric, randomized, controlled trial with a parallel group design (vegan (VD) vs. meat-rich (MD)) with 53 healthy, omnivore, normal-weight participants (62% female, mean 31 years of age), fecal samples were collected at the beginning and at the end of the trial and were analyzed using 16S rRNA gene amplicon sequencing (Clinical Trial register: DRKS00011963). Alpha diversity as well as beta diversity did not differ significantly between MD and VD. Plotting of baseline and end samples emphasized a highly intra-individual microbial composition. Overall, the gut microbiota was not remarkably altered between VD and MD after the trial. Coprococcus was found to be increased in VD while being decreased in MD. Roseburia and Faecalibacterium were increased in MD while being decreased in VD. Importantly, changes in genera Coprococcus, Roseburia and Faecalibacterium should be subjected to intense investigation as markers for physical and mental health.
Iron Isotopes Reveal a Benthic Iron Shuttle in the Palaeoproterozoic Zaonega Formation: Basinal Restriction, Euxinia, and the Effect on Global Palaeoredox Proxies
Authors: Mänd Kaarel , Lalonde Stefan V. , Paiste Kärt , Thoby Marie , Lumiste Kaarel , Robbins Leslie J. , Kreitsmann Timmu , Romashkin Alexander E. , Kirsimäe Kalle , Lepland Aivo , Konhauser Kurt O.
Published: March 2021

The Zaonega Formation in northwest Russia (~2.0 billion years old) is amongst the most complete successions that record the middle of the Palaeoproterozoic era. As such, geochemical data from the formation have played a central role in framing the debate over redox dynamics in the aftermath of the Great Oxidation Event (GOE). However, uncertainty over local redox conditions and the degree of hydrographic restriction in the formation has led to contradictory interpretations regarding global oxygen (O2) fugacity. Here, we provide new iron (Fe) isotope data together with major and trace element concentrations to constrain the local physiochemical conditions. The Zaonega Formation sediments show authigenic Fe accumulation (Fe/Al ≫ 1 wt.%/wt.%) and δ56Fe ranging from −0.58‰ to +0.60‰. Many of the data fall on a negative Fe/Al versus δ56Fe trend, diagnostic of a benthic Fe shuttle, which implies that Zaonega Formation rocks formed in a redox-stratified and semi-restricted basin. However, basin restriction did not coincide with diminished trace metal enrichment, likely due to episodes of deep-water exchange with metal-rich oxygenated seawater, as evidenced by simultaneous authigenic Fe(III) precipitation. If so, the Onega Basin maintained a connection that allowed its sediments to record signals of global ocean chemistry despite significant basinal effects.
Bioinspired Green Synthesis of Zinc Oxide Nanoparticles from a Native Bacillus cereus Strain RNT6: Characterization and Antibacterial Activity against Rice Panicle Blight Pathogens Burkholderia glumae and B. gladioli
Authors: Ahmed Temoor , Wu Zhifeng , Jiang Hubiao , Luo Jinyan , Noman Muhammad , Shahid Muhammad , Manzoor Irfan , Allemailem Khaled S. , Alrumaihi Faris , Li Bin
Published: March 2021

Burkholderia glumae and B. gladioli are seed-borne rice pathogens that cause bacterial panicle blight (BPB) disease, resulting in huge rice yield losses worldwide. However, the excessive use of chemical pesticides in agriculture has led to an increase in environmental toxicity. Microbe-mediated nanoparticles (NPs) have recently gained significant attention owing to their promising application in plant disease control. In the current study, we biologically synthesize zinc oxide nanoparticles (ZnONPs) from a native Bacillus cereus RNT6 strain, which was taxonomically identified using 16S rRNA gene analysis. The biosynthesis of ZnONPs in the reaction mixture was confirmed by using UV–Vis spectroscopy. Moreover, XRD, FTIR, SEM-EDS, and TEM analysis revealed the functional groups, crystalline nature, and spherical shape of ZnONPs with sizes ranging from 21 to 35 nm, respectively. Biogenic ZnONPs showed significant antibacterial activity at 50 µg mL−1 against B. glumae and B. gladioli with a 2.83 cm and 2.18 cm zone of inhibition, respectively, while cell numbers (measured by OD600) of the two pathogens in broth culture were reduced by 71.2% and 68.1%, respectively. The ultrastructure studies revealed the morphological damage in ZnONPs-treated B. glumae and B. gladioli cells as compared to the corresponding control. The results of this study revealed that ZnONPs could be considered as promising nanopesticides to control BPB disease in rice.
Light Activation of Nanocrystalline Metal Oxides for Gas Sensing: Principles, Achievements, Challenges
Authors: Chizhov Artem , Rumyantseva Marina , Gaskov Alexander
Published: March 2021

The review deals with issues related to the principle of operation of resistive semiconductor gas sensors and the use of light activation instead of thermal heating when detecting gases. Information on the photoelectric and optical properties of nanocrystalline oxides SnO2, ZnO, In2O3, and WO3, which are the most widely used sensitive materials for semiconductor gas sensors, is presented. The activation of the gas sensitivity of semiconductor materials by both UV and visible light is considered. When activated by UV light, the typical approaches for creating materials are (i) the use of individual metal oxides, (ii) chemical modification with nanoparticles of noble metals and their oxides, (iii) and the creation of nanocomposite materials based on metal oxides. In the case of visible light activation, the approaches used to enhance the photo- and gas sensitivity of wide-gap metal oxides are (i) doping; (ii) spectral sensitization using dyes, narrow-gap semiconductor particles, and quantum dots; and (iii) addition of plasmon nanoparticles. Next, approaches to the description of the mechanism of the sensor response of semiconductor sensors under the action of light are considered.
Impact of Maternal Nutritional Supplementation during Pregnancy and Lactation on the Infant Gut or Breastmilk Microbiota: A Systematic Review
Authors: Zaidi Aneesa Z. , Moore Sophie E. , Okala Sandra G.
Published: March 2021

Recent evidence indicates that maternal dietary intake, including dietary supplements, during pregnancy and lactation may alter the infant gut or breastmilk microbiota, with implications for health outcomes in both the mother and infant. To review the effects of maternal nutritional supplementation during pregnancy and lactation on the infant gut or breastmilk microbiota a systematic literature search was conducted. A total of 967 studies published until February 2020 were found, 31 were eligible and 29 randomized control trials were included in the qualitative synthesis. There were 23 studies that investigated the effects of probiotic supplementation, with the remaining studies investigating vitamin D, prebiotics or lipid-based nutrient supplements (LNS). The effects of maternal nutritional supplementation on the infant gut microbiota or breastmilk microbiota were examined in 21 and 12 studies, respectively. Maternal probiotic supplementation during pregnancy and lactation generally resulted in the probiotic colonization of the infant gut microbiota, and although most studies also reported alterations in the infant gut bacterial loads, there was limited evidence of effects on bacterial diversity. The data available show that maternal probiotic supplementation during pregnancy or lactation results in probiotic colonization of the breastmilk microbiota. There were no observed effects between probiotic supplementation and breastmilk bacterial counts of healthy women, however, administration of Lactobacillus probiotic to nursing women affected by mastitis was associated with significant reductions in breastmilk Staphylococcal loads. Maternal LNS supplementation during pregnancy and lactation increased bacterial diversity in the infant gut, whilst vitamin D and prebiotic supplementation did not alter either infant gut bacterial diversity or counts. Heterogeneity in study design precludes any firm conclusions on the effects of maternal nutritional supplementation during pregnancy and lactation on the infant gut or breastmilk microbiota, warranting further research.
SOA-Based Multilevel Polarization Shift On–Off Keying Transmission for Free-Space Optical Communication
Authors: Hong Yan-Qing , Kwon Do-Hoon , Choi Jae-Young , Ha In-Ho , Shin Won-Ho , Han Sang-Kook
Published: March 2021

This paper proposes a semiconductor optical amplifier (SOA)-based multilevel polarization shift on–off keying (MPS-OOK) transmission for free-space optical (FSO) communication. At the transmitter end, the MPS-OOK signal is modulated with a constant linear state of polarization (SOP) at the high-intensity level and various SOPs at the low-intensity level in order to improve the spectral efficiency (SE) with the transmitted power efficiency. At the receiver end, first, a polarization-independent SOA was introduced to optically suppress the turbulence-induced scintillation effect and equalize the intensities of the various SOPs in the deep gain saturation state without polarization distortion. Then, a linear polarizer (LP) with a high extinction ratio (ER) was deployed to convert the equalized SOPs into a known intensity. Finally, the converted MPS-OOK signal was detected using a single photodiode (PD) and distinguished using a multilevel fixed-threshold decision (M-FTD). The proposed technique was evaluated using experiments. A Mach–Zehnder modulator (MZM)-based fading simulator was introduced to emulate the turbulence-induced scintillation effect. The experimental results demonstrated that the scintillation effect was effectively mitigated and the SE was improved by up to 2 bit/s/Hz using the proposed four-level polarization shift on–off keying (4PS-OOK) transmission.
RNA Sequencing Reveals Rice Genes Involved in Male Reproductive Development under Temperature Alteration
Authors: Khlaimongkhon Sudthana , Chakhonkaen Sriprapai , Tongmark Keasinee , Sangarwut Numphet , Panyawut Natjaree , Wasinanon Thiwawan , Sikaewtung Kannika , Wanchana Samart , Mongkolsiriwatana Chareerat , Chunwonges Julapark , Muangprom Amorntip
Published: March 2021

Rice (Oryza sativa L.) is one of the most important food crops, providing food for nearly half of the world population. Rice grain yields are affected by temperature changes. Temperature stresses, both low and high, affect male reproductive development, resulting in yield reduction. Thermosensitive genic male sterility (TGMS) rice is sterile at high temperature and fertile at low temperature conditions, facilitating hybrid production, and is a good model to study effects of temperatures on male development. Semithin sections of the anthers of a TGMS rice line under low (fertile) and high (sterile) temperature conditions showed differences starting from the dyad stage, suggesting that genes involved in male development play a role during postmeiotic microspore development. Using RNA sequencing (RNA-Seq), transcriptional profiling of TGMS rice panicles at the dyad stage revealed 232 genes showing differential expression (DEGs) in a sterile, compared to a fertile, condition. Using qRT-PCR to study expression of 20 selected DEGs using panicles of TGMS and wild type rice plants grown under low and high temperature conditions, revealed that six out of the 20 selected genes may be unique to TGMS, while the other 14 genes showed common responses to temperatures in both TGMS and wild-type rice plants. The results presented here would be useful for further investigation into molecular mechanisms controlling TGMS and rice responses to temperature alteration.
Systematic Analysis of Combined Antioxidant and Membrane-Stabilizing Properties of Several Lamiaceae Family Kazakhstani Plants for Potential Production of Tea Beverages
Authors: Ydyrys Alibek , Zhaparkulova Nazgul , Aralbaeva Arailym , Mamataeva Aigul , Seilkhan Ainur , Syraiyl Sayagul , Murzakhmetova Maіra
Published: March 2021

One of the most important compounds that exhibit a wide range of biological activities with especially strong antioxidant action are plant polyphenols. In the course of the experiment, the dose-dependent effects of polyphenols-rich extracts isolated from the Lamiaceae family Kazakhstani plants were studied on the processes of lipid peroxidation and on the degree of erythrocytes hemolysis. The activity of aqueous-ethanolic extracts from dried parts of plants, such as Origanum vulgare, Ziziphora bungeana, Dracocephalum integrifolium, Mentha piperita, Leonurus turkestanicus, Thymus serpyllum, and Salvia officinalis, was studied in a Wistar rat model. Lipid peroxidation (LPO) in liver microsomes was assessed by measuring malondialdehyde content in the form of thiobarbituric acid-reacting substances (TBARS). Estimation of osmotic resistance of isolated erythrocytes was evaluated based on hemoglobin absorbance. The amount of total phenolics in the extracts was measured using the Folin-Ciocalteu reagent method. Based on the results, Thymus serpyllum extract exhibited a significantly higher antioxidant activity (IC50 = 3.3 ± 0.7) compared to other plant extracts. Accordingly, among the extracts studied, those from Salvia officinalis, Thymus serpyllum, and Origanum vulgare show the most pronounced membrane-stabilizing activity. Antioxidant and antihemolytic properties of green tea and Origanum vulgare extract mixtures were similar to that of each individual plant extract. Similar results were obtained when the green tea extract was mixed with Mentha piperita, Ziziphora bungeana, and Dracocephalum integrifolium extracts, indicating no discernible synergistic interaction.
Development of a Cell Suspension Culture System for Promoting Alkaloid and Vinca Alkaloid Biosynthesis Using Endophytic Fungi Isolated from Local Catharanthus roseus
Authors: Linh Tran My , Mai Nguyen Chi , Hoe Pham Thi , Ngoc Ninh Thi , Thao Phan Thi Hong , Ban Ninh Khac , Van Nguyen Tuong
Published: March 2021

Cell and tissue cultures of Catharanthus roseus have been studied extensively as an alternative strategy to improve the production of valuable secondary metabolites. The purpose of this study was to produce C. roseus callus and suspension cell biomass of good quality and quantity to improve the total alkaloids and bis-indole alkaloids. The young stem derived-callus of C. roseus variety Quang Ninh (QN) was grown on MS medium supplemented with 1.5 mg/L 2,4-dichlorophenoxyacetic acid (2,4-D) plus 1.5 mg/L kinetin, and the growth rate increased by 67-fold after 20 days. The optimal conditions for maintaining the cell suspension culture were 150 mg/50 mL cell inoculum, a medium pH of 5.5 and a culture temperature of 25 °C. The low alkaloid content in the culture was compensated for by using endophytic fungi isolated from local C. roseus. Cell extracts of endophytic fungi—identified as Fusarium solani RN1 and Chaetomium funicola RN3—were found to significantly promote alkaloid accumulation. This elicitation also stimulated the accumulation of a tested bis-indole alkaloid, vinblastine. The findings are important for investigating the effects of fungal elicitors on the biosynthesis of vinblastine and vincristine, as well as other terpenoid indole alkaloids (TIAs), in C. roseus QN cell suspension cultures.
Experimental Study on Distillation Column Parameters for Liquefaction Device of Low Concentration Coalbed Methane
Authors: Xiao Lu , Chen Jinhua
Published: March 2021

The input-output ratio and comprehensive energy consumption of low concentration coalbed methane cryogenic liquefaction devices are determined by the process parameters in control of the distillation column. In order to accurately control the actual operation process of the distillation column, the effect of the operating temperature of the distillation column on the liquefaction performance of a cold box was studied experimentally, and the optimal control parameters of the distillation column were obtained. The results show that the recovery rate of methane decreases with the increase in temperature at the top of the distillation column, and when this temperature is higher than −178 °C, the methane recovery rate drops sharply to below 90%. When the temperature at the bottom of the distillation column rises from −154 °C to −142.7 °C, the purity of LNG products is improved, and when this temperature is increased to −143.5 °C, the purity of products at the bottom of the distillation column reaches the standard, and can be stored safely. In actual operation, the evaporation temperature at the bottom of the column should not be higher than −140 °C. In the process of industrial plant design, measures should be taken to reduce the interaction of the temperature regulation at the top and bottom of the distillation column. When selecting the refrigerant circulation compressor, the leakage of the refrigerant should be considered to maintain the operating pressure of the refrigeration cycle.
Combination Therapy Involving Lavandula angustifolia and Its Derivatives in Exhibiting Antimicrobial Properties and Combatting Antimicrobial Resistance: Current Challenges and Future Prospects
Authors: Leong Wye-Hong , Lai Kok-Song , Lim Swee-Hua Erin
Published: March 2021

Antimicrobial resistance (AMR) has been identified as one of the biggest health threats in the world. Current therapeutic options for common infections are markedly limited due to the emergence of multidrug resistant pathogens in the community and the hospitals. The role of different essential oils (EOs) and their derivatives in exhibiting antimicrobial properties has been widely elucidated with their respective mechanisms of action. Recently, there has been a heightened emphasis on lavender essential oil (LEO)’s antimicrobial properties and wound healing effects. However, to date, there has been no review published examining the antimicrobial benefits of lavender essential oil, specifically. Previous literature has shown that LEO and its constituents act synergistically with different antimicrobial agents to potentiate the antimicrobial activity. For the past decade, encapsulation of EOs with nanoparticles has been widely practiced due to increased antimicrobial effects and greater bioavailability as compared to non-encapsulated oils. Therefore, this review intends to provide an insight into the different aspects of antimicrobial activity exhibited by LEO and its constituents, discuss the synergistic effects displayed by combinatory therapy involving LEO, as well as to explore the significance of nano-encapsulation in boosting the antimicrobial effects of LEO; it is aimed that from the integration of these knowledge areas, combating AMR will be more than just a possibility.
Implementing TRIZ with Supply Chain Management in New Product Development for Small and Medium Enterprises
Authors: Lin Yun-Sheng , Chen Mingchih
Published: March 2021

Due to the impact of globalization, the competition between enterprises has become fierce and led the supply chains of many industries to be reorganized. One of the consequences is that the operation of many small and medium enterprises (SMs) had become very difficult. Hence, many of SMEs in Taiwan have gone bankrupt and some of them have moved to other places where they have lower production costs, in order to survive; this not only hollowed out the industries but also disconnected the supply chains in their mother countries. Because Taiwan’s SMEs are generally poor in innovation, this study explored the implementation of the theory of inventive problem-solving (TRIZ) with alignment of new product development (NPD) and supply chain management (SCM) to strengthen the innovation and productivity of new products, so that SMEs can refer to its use to aid sustainable business operation. We considered an SME in Taiwan as a case to study and investigate the strategies that it employed to achieve survival and sustainability. By examining the practical applications of the NPD of the case company, which was based on the TRIZ and NPD SCM alignment, we found that value-added products may be created despite unfavorable industry environments, by implementing and coordinating the TRIZ and three product-related variables, namely innovating, modularity, and variety. This study explored practical alternatives for SMEs to develop various value-added products that meet customers’ changing requirements and succeed in competitive markets to achieve a sustainable business operation. Considering SMEs are crucially important to the economic equality and development of countries and that SMEs may only survive for a short time when operating in changing supply chain environments, this study can be used as a reference for the management of SMEs and future academic research in related fields.
Use of Biological Dosimetry for Monitoring Medical Workers Occupationally Exposed to Ionizing Radiation
Authors: Piotrowski Igor , Dawid Aleksandra , Kulcenty Katarzyna , Suchorska Wiktoria Maria
Published: March 2021

Medical workers are the largest group exposed to man-made sources of ionizing radiation. The annual doses received by medical workers have decreased over the last several decades, however for some applications, like fluoroscopically guided procedures, the occupational doses still remain relatively high. Studies show that for some procedures the operator and staff still use insufficient protective and dosimetric equipment, which might cause an underestimation of medical exposures. Physical dosimetry methods are a staple for estimating occupational exposures, although due to the inconsistent use of protection measures, an alternative method such as biological dosimetry might complement the physical methods to achieve a more complete picture. Such methods were used to detect exposures to doses as low as 0.1 mSv/year, and could be useful for a more accurate assessment of genotoxic effects of ionizing radiation in medical workers. Biological dosimetry is usually based on the measurement of the effects present in peripheral blood lymphocytes. Although some methods, such as chromosome aberration scoring or micronucleus assay, show promising results, currently there is no one method recognized as most suitable for dosimetric application in the case of chronic, low-dose exposures. In this review we decided to evaluate different methods used for biological dosimetry in assessment of occupational exposures of medical workers.
Driving Stress Detection Using Multimodal Convolutional Neural Networks with Nonlinear Representation of Short-Term Physiological Signals
Authors: Lee Jaewon , Lee Hyeonjeong , Shin Miyoung
Published: March 2021

Mental stress can lead to traffic accidents by reducing a driver’s concentration or increasing fatigue while driving. In recent years, demand for methods to detect drivers’ stress in advance to prevent dangerous situations increased. Thus, we propose a novel method for detecting driving stress using nonlinear representations of short-term (30 s or less) physiological signals for multimodal convolutional neural networks (CNNs). Specifically, from hand/foot galvanic skin response (HGSR, FGSR) and heart rate (HR) short-term input signals, first, we generate corresponding two-dimensional nonlinear representations called continuous recurrence plots (Cont-RPs). Second, from the Cont-RPs, we use multimodal CNNs to automatically extract FGSR, HGSR, and HR signal representative features that can effectively differentiate between stressed and relaxed states. Lastly, we concatenate the three extracted features into one integrated representation vector, which we feed to a fully connected layer to perform classification. For the evaluation, we use a public stress dataset collected from actual driving environments. Experimental results show that the proposed method demonstrates superior performance for 30-s signals, with an overall accuracy of 95.67%, an approximately 2.5–3% improvement compared with that of previous works. Additionally, for 10-s signals, the proposed method achieves 92.33% classification accuracy, which is similar to or better than the performance of other methods using long-term signals (over 100 s).
W-Band Multi-Aspect High Resolution Range Profile Radar Target Classification Using Support Vector Machines
Authors: Jasinski Tomasz , Brooker Graham , Antipov Irina
Published: March 2021

Millimeter-wave (W-band) radar measurements were taken for two maritime targets instrumented with attitude and heading reference systems (AHRSs) in a littoral environment with the aim of developing a multiaspect classifier. The focus was on resource-limited implementations such as short-range, tactical, unmanned aircraft systems (UASs) and dealing with limited and imbalanced datasets. Radar imaging and preprocessing consisted of recording high-resolution range profiles (HRRPs) and performing range alignment using peak detection and fast Fourier transforms (FFTs). HRRPs were used because of their simplicity, reliability, and speed. The features used were fixed-length, frequency domain range profiles. Two linear support vector machine (SVM)-based classifiers were developed which both yielded excellent results in their general forms and were simple to implement. The first approach utilized the positive predictive value (PPV) and negative predictive value (NPV) statistics of the SVM directly to generate target probabilities and consequently determine the optimal aspect transitions for classification. The second approach used the Kolmogorov–Smirnov test for dimensionality reduction, followed by concatenating feature vectors across several aspects. The latter approach is particularly well-suited to resource-constrained scenarios, potentially allowing for retraining and updating in the field.
Endoluminal Motion Recognition of a Magnetically-Guided Capsule Endoscope Based on Capsule-Tissue Interaction Force
Authors: Zhang Peisen , Li Jing , Zhang Weimin , Hao Yang , Ciuti Gastone , Arai Tatsuo , Dario Paolo , Huang Qiang
Published: March 2021

A magnetically-guided capsule endoscope, embedding flexible force sensors, is designed to measure the capsule-tissue interaction force. The flexible force sensor is composed of eight force-sensitive elements surrounding the internal permanent magnet (IPM). The control of interaction force acting on the intestinal wall can reduce patient’s discomfort and maintain the magnetic coupling between the external permanent magnet (EPM) and the IPM during capsule navigation. A flexible force sensor can achieve this control. In particular, by analyzing the signals of the force sensitive elements, we propose a method to recognize the status of the motion of the magnetic capsule, and provide corresponding formulas to evaluate whether the magnetic capsule follows the motion of the external driving magnet. Accuracy of the motion recognition in Ex Vivo tests reached 94% when the EPM was translated along the longitudinal axis. In addition, a method is proposed to realign the EPM and the IPM before the loss of their magnetic coupling. Its translational error, rotational error, and runtime are 7.04 ± 0.71 mm, 3.13 ± 0.47∘, and 11.4 ± 0.39 s, respectively. Finally, a control strategy is proposed to prevent the magnetic capsule endoscope from losing control during the magnetically-guided capsule colonoscopy.
Analysis of Fibre Cross-Coupling Mechanisms in Fibre-Optical Force Sensors
Authors: Bunge Christian-Alexander , Kallweit Jan , Colakoglu Levent , Gries Thomas
Published: March 2021

The force-enhanced light coupling between two optical fibres is investigated for the application in a pressure or force sensor, which can be arranged into arrays and integrated into textile surfaces. The optical coupling mechanisms such as the influence of the applied force, the losses at the coupling point and the angular alignment of the two fibres are studied experimentally and numerically. The results reveal that most of the losses occur at the deformation of the pump fibre. Only a small percentage of the cross-coupled light from the pump fibre is actually captured by the probe fibre. Thus, the coupling and therefore the sensor signal can be strongly increased by a proper crossing angle between the fibres, which lead to a coupling efficiency of 3%, a sensitivity improvement of more than 20 dB compared to the orthogonal alignment of the two fibres.
Symbolic Interactions in Popular Religion According to Dimensions of Religiosity: A Qualitative Study
Authors: Kovačević Vlaho , Malenica Krunoslav , Kardum Goran
Published: March 2021

The purpose of this paper was to interpret the usage of symbols in popular religion based on contemporary symbolic interactionism using the reference framework of the symbolic community. The strength of the chosen symbolic interactionist approach is primarily in the research of the role of different dimensions of the religious in understanding the meaning of popular religion in the symbolic community. The qualitative approach and the method of in-depth semi-structured interviews were employed in the research, which responded to the main goal of the research on the meanings the participants of the popular religion attach to the symbolic interactions. A deliberate sample was used for the selection of participants in the popular forms of celebrating the days of Our Lady of Vrpolje, Our Lady of Sinj, and Our Lady of Karavaj as well as the Guardians of Christ’s grave in Vodice, Croatia. According to the results, popular religion, transmitted through visible signs, places believers in a position of physical contact with the supernatural world within a symbolic environment. To achieve this, popular religion displays a need for sacred images, words, sounds, signs, movements, smells. Believers in popular religion seek to establish as simple, intimate, and direct relationship with a deity as possible. The respondents’ answers confirm that the experiential dimension of religiosity is lived primarily on a personal level that precedes the social dimension. For the participants, the religious community has a symbolic character in terms of creating strong bonds between members of society or a social group, especially within the symbolic meaning of a feast day.
The Border Harms of Human Displacement: Harsh Landscapes and Human Rights Violations
Authors: Ilcan Suzan
Published: March 2021

Building on the work of critical migration and border studies, particularly the scholarship on the suffering of displaced people through border-related violence, the article focuses on bordering practices and human rights violations relating to the Syrian civil war. It advances the argument that during peoples’ fragmented journeys to seek safety and protection within and outside of Syria, which are often punctuated by stops and starts, they encounter one or more of three kinds of bordering practices—hardening of borders, expansion of borders, and pushbacks—that can injure them and violate international human rights and often the principle of non-refoulement. The article refers to these encounters as the “border harms of human displacement”. The analysis emphasizes the experiences of people on the move and the cruelties and spatial violence they endure. The latter include lengthy periods of walking and running, travel across hazardous lands and seas, family separation, state restrictions, and mistreatment by border authorities. Yet, in response to such difficulties, they continue to assert their agency by negotiating bordering practices and harsh landscapes.
Gender Differences in the Mitigating Effect of Co-Parenting on Parental Burnout: The Gender Dimension Applied to COVID-19 Restrictions and Parental Burnout Levels
Authors: Bastiaansen Coco , Verspeek Emmie , van Bakel Hedwig
Published: March 2021

Parenting is recognized as a complex and stressful activity, which in recent years has been linked to the potential development of parental burnout among mothers and fathers. With the spread of COVID-19 around the globe, not only have situations of health emergency and economic difficulty emerged, but also tremendous impacts on individual lives and family role divisions, which continue to be experienced today. As lockdown measures have affected unemployment rates, financial insecurity levels, social support, amount of leisure time, and the number of caring responsibilities, parents are expected to be at higher risk for developing parental burnout. Co-parenting is presented as a factor which can mitigate the effect between COVID-19 lockdown measures and the levels of experienced parental burnout. Nevertheless, we argue that the role of co-parenting in association with the implications of COVID-19 on parental stress differs between men and women. As parenthood remains an activity that is largely gender-based, co-parenting is hypothesized to be of more crucial importance in attenuating the effect between COVID-19 lockdown measures and parental burnout for fathers in comparison to mothers. Our results confirm previous findings that COVID-19 has increased levels of parental burnout. The relationship between state-imposed COVID-19 lockdown measures and levels of parental burnout was not found to be significantly affected by co-parenting. However, when assessing this two-way interaction separately for men and women, we saw that this mitigating effect was significant for fathers and non-significant for mothers.
Evaluating Ways to Form a Sense of Community in a Shrinking City: The Case of the Media Culture Center, Seocheon, South Korea
Authors: Lee Jin-Wook
Published: March 2021

The objective of this study was to promote communal spirit through cultural space in a shrinking city. To achieve this, the study tracked the operation method of the Media Culture Center in Seocheon of South Korea; collected data by interviewing stakeholders, such as operators, participants, and residents; and analyzed the data using an open coding method. The results of this study showed that it was necessary to (1) provide appropriate services for the region, (2) support cultural activities aimed at common goals, and (3) serve as a stronghold for regional governance to promote communal spirit through a cultural space. The results suggested the following implications when forming communal spirit in a shrinking city. First, it is possible to form communal spirit in a shrinking city through a cultural space; operating a program that can help people overcome geographical limitations is necessary for this. Second, it requires experts who understand the region well and who derive residents’ participation and consent well as a facilitating factor in the formation of communal spirit. Third, since the common goal reinforces communal spirit, political support is needed to facilitate the community in participating in an event together.
A Case Series Describing the Recurrence of COVID-19 in Patients Who Recovered from Initial Illness in Bangladesh
Authors: Das Pritimoy , Satter Syed M. , Ross Allen G. , Abdullah Zarin , Nazneen Arifa , Sultana Rebeca , Rimi Nadia Ali , Chowdhury Kamal , Alam Rashedul , Parveen Shahana , Rahman Md Mahfuzur , Hossain Mohammad Enayet , Rahman Mohammed Ziaur , Mazumder Razib , Abdullah Ahmed , Rahman Mahmudur , Banu Sayera , Ahmed Tahmeed , Clemens John D. , Rahman Mustafizur
Published: March 2021

To date, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has infected over 80 million people globally. We report a case series of five clinically and laboratory confirmed COVID-19 patients from Bangladesh who suffered a second episode of COVID-19 illness after 70 symptom-free days. The International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), is a leading public health research institution in South Asia. icddr, b staff were actively tested, treated and followed-up for COVID-19 by an experienced team of clinicians, epidemiologists, and virologists. From 21 March to 30 September 2020, 1370 icddr,b employees working at either the Dhaka (urban) or Matlab (rural) clinical sites were tested for COVID-19. In total, 522 (38%) were positive; 38% from urban Dhaka (483/1261) and 36% from the rural clinical site Matlab (39/109). Five patients (60% male with a mean age of 41 years) had real-time reverse transcription-polymerase chain reaction (rRT-PCR) diagnosed recurrence (reinfection) of SARS-CoV-2. All had mild symptoms except for one who was hospitalized. Though all cases reported fair risk perceptions towards COVID-19, all had potential exposure sources for reinfection. After a second course of treatment and home isolation, all patients fully recovered. Our findings suggest the need for COVID-19 vaccination and continuing other preventive measures to further mitigate the pandemic. An optimal post-recovery follow-up strategy to allow the safe return of COVID-19 patients to the workforce may be considered.
Blocks Size Frequency Distribution in the Enceladus Tiger Stripes Area: Implications on Their Formative Processes
Authors: Pajola Maurizio , Lucchetti Alice , Senter Lara , Cremonese Gabriele
Published: March 2021

We study the size frequency distribution of the blocks located in the deeply fractured, geologically active Enceladus South Polar Terrain with the aim to suggest their formative mechanisms. Through the Cassini ISS images, we identify ~17,000 blocks with sizes ranging from ~25 m to 366 m, and located at different distances from the Damascus, Baghdad and Cairo Sulci. On all counts and for both Damascus and Baghdad cases, the power-law fitting curve has an index that is similar to the one obtained on the deeply fractured, actively sublimating Hathor cliff on comet 67P/Churyumov-Gerasimenko, where several non-dislodged blocks are observed. This suggests that as for 67P, sublimation and surface stresses favor similar fractures development in the Enceladus icy matrix, hence resulting in comparable block disaggregation. A steeper power-law index for Cairo counts may suggest a higher degree of fragmentation, which could be the result of localized, stronger tectonic disruption of lithospheric ice. Eventually, we show that the smallest blocks identified are located from tens of m to 20–25 km from the Sulci fissures, while the largest blocks are found closer to the tiger stripes. This result supports the ejection hypothesis mechanism as the possible source of blocks.
Stratification: An Entropic View of Society’s Structure
Authors: Sargentis G.-Fivos , Iliopoulou Theano , Dimitriadis Panayiotis , Mamassis Nikolaos , Koutsoyiannis Demetris
Published: March 2021

In human societies, we observe a wide range of types of stratification, i.e., in terms of financial class, political power, level of education, sanctity, and military force. In financial, political, and social sciences, stratification is one of the most important issues and tools as the Lorenz Curve and the Gini Coefficient have been developed to describe some of its aspects. Stratification is greatly dependent on the access of people to wealth. By “wealth”, we mean the quantified prosperity which increases the life expectancy of people. Prosperity is also connected to the water-food-energy nexus which is necessary for human survival. Analyzing proxies of the water-food-energy nexus, we suggest that the best proxy for prosperity is energy, which is closely related to Gross Domestic Product (GDP) per capita and life expectancy. In order to describe the dynamics of social stratification, we formulate an entropic view of wealth in human societies. An entropic approach to income distribution, approximated as available energy in prehistoric societies, till present-day economies, shows that stratification can be viewed as a stochastic process subject to the principle of maximum entropy and occurring when limits to the wealth of society are set, either by the political and economic system and/or by the limits of available technology.
Increased reliability Cleanup engine and transmissions of tractors using nanomaterials
Authors: Lyalyakin V. P. , Gitelman D. A. , Solovev R. Yu. , Olhovatsky A. K.
Published: March 2021

The article presents some of the results and the results of the study to reduce the operational running and improving engine reliability, renovated CLD SHP, using nanomaterials.
Doctor–patient interactions that exclude patients experiencing homelessness from health services: an ethnographic exploration
Authors: O'Carroll Austin , Wainwright David
Published: March 2021

Background

People experiencing homelessness have poor health indices and poor access to health care. Their health service utilisation (HSU) is typified by: late illness presentations; poor attendance rates at appointments; low usage of primary care services and outpatient departments; and high utilisation of emergency departments and inpatient services. Why people experiencing homelessness have these particular HSU patterns is poorly understood.

Aim

This research sought to explore barriers to health service usage for people experiencing homelessness.

Design & setting

The authors conducted critical realist ethnography over 13 months in Dublin with people experiencing homelessness at four purposively chosen sites (a food hall, a drop-in centre, an emergency department, and an outreach service for rough sleepers).

Method

Ethnographic research was supplemented with focus groups of hospital doctors and people experiencing homelessness, and with 50 semi-structured interviews with people experiencing homelessness. The epistemological framework was critical realism.

Results

One of the factors identified in the research as contributing to the HSU pattern of people experiencing homelessness was recurrent interactions between health professionals and patients, whereby patients were either excluded or discouraged from attending health services, or self-excluded themselves from services. These interactions were described as ’conversations of exclusion’. Four such conversations were described: ‘the benzodiazepine conversation‘; ‘the mistrustful conversation‘; ‘the blaming conversation‘; and ‘the assertive conversation’.

Conclusion

There are certain recurrent interactions between people experiencing homelessness and doctors that result in the exclusion of people experiencing homelessness from health services.
Evaluation of a primary care-based collaborative care model (PARTNERS2) for people with diagnoses of schizophrenia, bipolar, or other psychoses: study protocol for a cluster randomised controlled trial
Authors: Plappert Humera , Hobson-Merrett Charley , Gibbons Bliss , Baker Elina , Bevan Sheridan , Clark Michael , Creanor Siobhan , Davies Linda , Denyer Rebecca , Frost Julia , Gask Linda , Gibson John , Gill Laura , Gwernan-Jones Ruth , Hardy Pollyanna , Hosking Joanne , Huxley Peter , Jeffrey Alison , Jones Benjamin , Marwaha Steven , Pinold Vanessa , Planner Claire , Rawcliffe Tim , Reilly Siobhan , Richards Debra , Williams Lynsey , Birchwood Max , Byng Richard
Published: March 2021

Background

Current NHS policy encourages an integrated approach to provision of mental and physical care for individuals with long term mental health problems. The ‘PARTNERS2’ complex intervention is designed to support individuals with psychosis in a primary care setting.

Aim

The trial will evaluate the clinical and cost-effectiveness of the PARTNERS2 intervention.

Design & setting

This is a cluster randomised controlled superiority trial comparing collaborative care (PARTNERS2) with usual care, with an internal pilot to assess feasibility. The setting will be primary care within four trial recruitment areas: Birmingham & Solihull, Cornwall, Plymouth, and Somerset. GP practices are randomised 1:1 to either (a) the PARTNERS2 intervention plus modified standard care (‘intervention’); or (b) standard care only (‘control’).

Method

PARTNERS2 is a flexible, general practice-based, person-centred, coaching-based intervention aimed at addressing mental health, physical health, and social care needs. Two hundred eligible individuals from 39 GP practices are taking part. They were recruited through identification from secondary and primary care databases. The primary hypothesis is quality of life (QOL). Secondary outcomes include: mental wellbeing, time use, recovery, and process of physical care. A process evaluation will assess fidelity of intervention delivery, test hypothesised mechanisms of action, and look for unintended consequences. An economic evaluation will estimate its cost-effectiveness. Intervention delivery and follow-up have been modified during the COVID-19 pandemic.

Conclusion

The overarching aim is to establish the clinical and cost-effectiveness of the model for adults with a diagnosis of schizophrenia, bipolar, or other types of psychoses.