bluuebunny/crossref_metadata_2025 huggingface dataset:
Hilbert spectrum based features for speech/music classification
Authors: Kumar Arvind , Solanki Sandeep , Chandra Mahesh
Published: July 2022

Automatic Speech/Music classification uses different signal processing techniques to categorize multimedia content into different classes. The proposed work explores Hilbert Spectrum (HS) obtained from different AM-FM components of an audio signal, also called Intrinsic Mode Functions (IMFs) to classify an incoming audio signal into speech/music signal. The HS is a twodimensional representation of instantaneous energies (IE) and instantaneous frequencies (IF) obtained using Hilbert Transform of the IMFs. This HS is further processed using Mel-filter bank and Discrete Cosine Transform (DCT) to generate novel IF and Instantaneous Amplitude (IA) based cepstral features. Validations of the results were done using three databases-Slaney Database, GTZAN and MUSAN database. To evaluate the general applicability of the proposed features, extensive experiments were conducted on different combination of audio files from S&S, GTZAN and MUSAN database and promising results are achieved. Finally, performance of the system is compared with performance of existing cepstral features and previous works in this domain.
Perioperative fully closed-loop insulin delivery in patients undergoing elective surgery: an open-label, randomised controlled trial
Authors: Herzig David , Suhner Simon , Roos Jonathan , Schürch Daniel , Cecchini Luca , Nakas Christos T , Weiss Salome , Kadner Alexander , Kocher Gregor J , Guensch Dominik P , Wilinska Malgorzata E , Raabe Andreas , Siebenrock Klaus A , Beldi Guido , Gloor Beat , Hovorka Roman , Vogt Andreas P , Bally Lia
Published: July 2022

  

Introduction: Perioperative management of glucose levels remains challenging. We aimed to assess whether fully closed-loop subcutaneous insulin delivery would improve glycaemic control compared with standard insulin therapy in insulin-requiring patients undergoing elective surgery.

Research Design and Methods: We did a single-centre, open-label, randomised controlled trial. Patients with diabetes (other than type 1) undergoing elective surgery were recruited from different surgery units and randomized using a minimisation schedule (stratified by HbA1c and daily insulin dose) to fully closed-loop insulin delivery with faster-acting insulin aspart (closed-loop group) or standard insulin therapy according to local clinical practice (control group). Study treatment was administered from hospital admission to discharge (for a maximum of 20 days). The primary endpoint was the proportion of time with sensor glucose in the target range (5.6-10.0 mmol/L).

Results: Forty-five patients were enrolled and assigned to the closed-loop (n=23) or the control group (n=22). One patient (closed-loop group) withdrew from the study before surgery and was not analysed. Participants underwent abdominal (57%), vascular (23%), orthopaedic (9%), neuro- (9%) or thoracic (2%) surgery. The mean proportion of time that sensor glucose was in the target range was 76.7±10.1% in the closed-loop and 54.7±20.8% in the control group (mean difference 22.0 percentage points [95% CI: 11.9-32.0%; p<0.001]). No episodes of severe hypoglycaemia (<3.0 mmol/L) or hyperglycaemia with ketonaemia nor any study-related adverse events occurred in either group.

Conclusion: In the context of mixed elective surgery, the use of fully closed-loop subcutaneous insulin delivery improves glucose control, without a higher risk of hypoglycaemia.
Deficient Caveolin-1 Synthesis in Adipocytes Stimulates Systemic Insulin-independent Glucose Uptake via Extracellular Vesicles
Authors: Crewe Clair , Chen Shiuhwei , Bu Dawei , Gliniak Christy M. , Asterholm Ingrid Wernstedt , Yu Xin Xin , Joffin Nolwenn , Souza Camila Oliveira de , Funcke Jan-Bernd , Oh Da Young , Varlamov Oleg , Robino Jacob J , Gordillo Ruth , Scherer Philipp E.
Published: July 2022

Caveolin-1 (cav1) is an important structural and signaling component of plasma membrane invaginations called caveolae and is abundant in adipocytes. As previously reported, adipocyte-specific ablation of the cav1 gene (ad-cav1KO mouse) does not result in elimination of the protein, as cav1 protein traffics to adipocytes from neighboring endothelial cells. However, this mouse is a functional knockout as adipocyte caveolar structures are depleted. Compared to controls, ad-cav1KO mice on a high-fat diet (HFD) display improved whole-body glucose clearance despite complete loss of glucose-stimulated insulin secretion, blunted insulin-stimulated AKT activation in metabolic tissues and partial lipodystrophy. The cause is increased insulin-independent glucose uptake by white adipose tissue (AT) and reduced hepatic gluconeogenesis. Furthermore, high fat fed ad-cav1KO mice display significant AT inflammation, fibrosis, mitochondrial dysfunction, and dysregulated lipid metabolism. The glucose clearance phenotype of the ad-cav1KO mice is at least partially mediated by AT small extracellular vesicles (AT-sEVs). Injection of control mice with AT-sEVs from ad-cav1KO mice phenocopies ad-cav1KO characteristics. Interestingly, AT-sEVs from ad-cav1KO mice propagate the phenotype of the AT to the liver. These data indicate that adipocyte cav1 is essential for healthy adaptation of the AT to overnutrition and prevents aberrant propagation of negative phenotypes to other organs by EVs.
Online in situ detection of kitchen environment based on laser-induced breakdown spectroscopy
Authors: Tian Dongpeng , Sun Zhongmou , Wan Enlai , Zhou Wentao , Chen Ziang , Liu Yuzhu
Published: July 2022

The damage of kitchen oil fume to the human body and environment cannot be ignored. Based on laser-induced breakdown spectroscopy (LIBS), five kitchen environments are online in situ detected, including the air scene, fry scene, grill scene, steam scene, and stew scene. In the spectra, characteristic elements such as C, H, O, and N are detected in the fry scene containing oil fume, and metal elements such as Mg, Ca, K, and Na are observed in the grill scene containing charcoal smoke. The spectra of five kitchen environments are tested and compared. In the measurement, except for the air scene, obvious carbon–nitrogen molecular spectral lines are detected. LIBS is combined with principal component analysis and backpropagation artificial neural network system to detect and analyze kitchen fumes. Finally, five kitchen scenes are analyzed and identified based on this system, and the final recognition accuracy is 98.60%.
A Comparison of American Women’s Experiences with Both Gestational Surrogate Pregnancies and Spontaneous Pregnancies
Authors:   Center for Bioethics and Culture, USA, Lahl Jennifer , Fell Kallie ,   Center for Bioethics and Culture, USA, Bassett Kate ,   Independent Data Scientist, USA, Broghammer Frances H. ,   Minnesota Department of Human Services, USA, Briggs William M. ,   Independent Statistician, USA
Published: July 2022

This article evaluates the pregnancy experiences of American women by comparing their spontaneous or non-surrogate pregnancies with their gestational surrogate pregnancies. Data were collected through structured interviews using an online video platform. In total, 96 interviews were conducted. Data revealed that a woman was more likely to have a pregnancy that was high-risk during a surrogate pregnancy than during a non-surrogate pregnancy, independent of maternal age or gravidity (OR 11.4, 3.5-36.6; p<.0001). A surrogate pregnancy had three times higher odds of resulting in a cesarean section (p<.0001) and was five times more likely to deliver at an earlier gestational age (p<.0001). Women in this study were significantly more likely to experience postpartum depression following the delivery of surrogate children than after delivering their non-surrogate children (p=.01), and overall, they were more likely to have adverse outcomes during a surrogate pregnancy. The rate of new post-surrogacy chronic health issues for women of color was significantly higher than for women identified as white (p<.0001). We found that women’s economic disadvantage was a major contributor to the decision to proceed with surrogacy. This study confirms that health disparities exist for women with surrogate pregnancies compared to non-surrogate pregnancies, which can lead to long-term complications after a surrogate pregnancy. In terms of biomedical ethics, it raises important social, economic, and political issues related to surrogacy, all requiring further exploration. Future research will build on the present work in further helping us to understand the circumstances and consequences involved for women in surrogacy.
Lessons in Linkage: Combining Administrative Data Using Deterministic Linkage for Surveillance of Sports and Recreation Injuries in Florida, United States
Authors: Baker Charlotte , Nottingham Quinton , Holloway Jonathan
Published: July 2022

ObjectivesPrevious and ongoing epidemiological surveillance of sports and recreation injuries (SRI) has been cross-sectional in nature, utilised a subset of injuries based on athletic trainer availability, or focused on elite and professional athletes. In the United States, surveillance is often prohibitively expensive and not well funded by national organisations or agencies, except for the case of some professional and elite sports. This paper details the methodology, barriers, and successes of using deterministic linkage to combine emergency department and hospitalisation data with a single identifier for use in surveilling sports injuries for persons aged 5 to 18 years.
DesignData linkage of a population cohort.
MethodsWe performed deterministic linkage of administrative emergency department and hospitalisation data from the state of Florida in the US. Data was acquired from the Florida Agency for Health Care Administration. With limited identifiers available due to privacy, we combined data across multiple years using a near universal identifier. We identified sport and recreation injuries using a modified External Cause of Injury Morbidity Matrix and ICD codes across all possible diagnoses. Finally, we obtained descriptive statistics of records that were successfully linked and those that were not to assess similarities between the groups.
ResultsWe found 384,731 visits for SRI over a seven-year period. We were able to link approximately 70% of the records using a single identifier. There were statistically significant differences by age, sex, payer, and race/ethnicity for the records that were linked compared to the records that were not linked.
ConclusionsThis study is significant because while similar methods have been used to examine other conditions (e.g. asthma), few have linked multiple types of administrative data especially with nearly no identifiers to examine sports and recreation injuries. This method was found useful to identify injuries over time for the same individuals seeking care in emergency departments, or in hospital inpatient settings, though future work will need to address the limitations of this method. If we expect to move health surveillance forward as budgets for it become even more limited, we must develop and improve methods to do it with fewer resources, including using data that has great limitations.
Keywordsdeterministic linkage; epidemiological methods; epidemiology; surveillance; public health; data cleaning; data linkage; reformatting; SAS; Python; injury surveillance; disease surveillance; health surveillance; biostatistics
Estimation of Genetic Parameters of Pinus wallichiana Seedlings in the Nursery
Authors:   Dept. of Silviculture and Agroforestry, Dr. Yaswant Singh Parmar University of Horticulture and Forestry, Solan, Himachal Pardesh (173 230), India, Kaur Amanpreet , Monga Rajesh ,   Research and Development, ITC-PSPD Unit Wimco Seedling, Rudrapur, Uttrakhand (263 153), India, Bhardwaj D. R. ,   Dept. of Silviculture and Agroforestry, Dr. Yaswant Singh Parmar University of Horticulture and Forestry, Solan, Himachal Pardesh (173 230), India, Sharma Jaipal ,   Dept. of Tree Improvement and Genetic Resources, Dr. Yaswant Singh Parmar University of Horticulture and Forestry, Solan, Himachal Pardesh (173 230), India
Published: July 2022

The present study was carried out at the Department of Silviculture and Agroforestry forest nursery, Dr. Y.S. Parmar UHF, Nauni, Solan, HP, India to estimate genetic parameters on seed germination and growth characters of Pinus wallichiana seedlings. Seeds were collected from different altitudinal ranges [1800–2100 (A1), 2100–2400 (A2), 2400–2700 (A3), >2700 (A4) m asl) of Himachal Pradesh in the year 2019–20. The seeds were sown under nursery using randomized block design with three replications. Data recorded for germination and growth character from 10 randomly selected seedlings of each replication and mean data were used for analysis. Analysis of variance revealed that the mean sum of squares were highly significant difference for most of the germination and growth traits. Irrespective of altitudes, the maximum environmental variance was reported in survival percentage (19.2%). The genotypic and phenotypic variance was recorded higher in germination capacity (76.3) and survival percentage (84.9), respectively. Along different altitudinal zones, the genotypic and phenotypic variance was higher at A2 altitude in germination percentage (77.3, 81.3), respectively. Heritability in a broad sense along elevation was more in most of the germination parameters at A2 and growth traits at A1, representing characters are least influenced by environment and selection of character’s is useful. Whereas, the genetic advance was more in germination capacity at A2 altitude indicating the best selection of population from this altitude. So, it would be concluded that seedlings collected from lower (1800–2100m asl)and mid altitudes (2100–2400m asl) were found suitable for large scale plantations in this area.
Performance Evaluation of Ginger Genotypes on their Yield and Nutrient Uptake under the Coastal Karnataka, India
Authors:   Dept. of Spices, Plantation, Medicinal and Aromatic Crops, University of Horticultural Sciences, Bagalkot, Karnataka (587 104), India, Y. Ravi , V. B. Narayanpur ,   Dept. of Spices, Plantation, Medicinal and Aromatic Crops, University of Horticultural Sciences, Bagalkot, Karnataka (587 104), India, P. M. Gangadharappa ,   Dept. of Spices, Plantation, Medicinal and Aromatic Crops, University of Horticultural Sciences, Bagalkot, Karnataka (587 104), India, J. S. Hiremath ,   Dept. of Spices, Plantation, Medicinal and Aromatic Crops, University of Horticultural Sciences, Bagalkot, Karnataka (587 104), India, T. Shantappa ,   RHREC, Dharwad, University of Horticultural Sciences, Bagalkot, Karnataka (587 104), India, A. Prashant ,   Dept. of Plant Pathology, 5Dept. of Genetics and Plant Breeding, University of Horticultural Sciences, Bagalkot, Karnataka (587 104), India, M. B. Doddamani ,   Dept. of Genetics and Plant Breeding, University of Horticultural Sciences, Bagalkot, Karnataka (587 104), India
Published: July 2022

A field experiment was conducted during kharif (June, 2014–January, 2015) at College of Horticulture, Sirsi, Karnataka, India to study the yield, yield attributing traits, nutrient content and nutrient uptake pattern in ginger genotypes. In the present study 16 ginger genotypes including nationally released varieties viz. IISR-Mahima, IISR-Varada, IISR-Rajatha, Suravi, Suprabha, Himagiri, Rio-de-Janeiro, Suruchi, Himachal, Karkal Local, Humanabad Local, Jorhat-1, Jorhat-2, Bidar-1, Bidar-2 and Shikaripura Local were selected with an aim to assess the yield performance of selected genotypes and varieties in order to determine nutrient content and absorption pattern. Research results indicate that among 16 ginger genotypes including national released varieties the genotype Humnabad Local has recorded maximum number of primary rhizomes (6.30) and secondary rhizomes (24.50), higher fresh rhizome yield (360.20 g plant-1) and yield ha-1 (21.55 t ha-1), dry recovery (27.35%). The genotype Bidar-1 recorded highest nitrogen content in rhizome (1.49%), whereas the variety IISR-Mahima recoded highest nitrogen content in root (1.16%) and in shoot (1.60%). Genotype Shikaripura local recorded maximum phosphorus content in rhizome (0.41%), root (0.39%) and in shoot (0.59%). Genotype Humnabad Local recorded highest potassium content in root (2.57%), whereas the variety IISR-Mahima recorded highest potassium content in rhizome (2.58%) and shoot (2.56%). The nutrient uptake pattern of ginger genotypes indicates that the ginger crop is potassium and nitrogen exhaustive. The results of this study provide a guideline for fertilizer application to ginger crop with respect to varieties, quantity and proportion of nutrient elements according to the demand of variety.
ANALISIS KEBUTUHAN PENINGKATAN MINAT PESERTA DIDIK LAKI-LAKI DALAM PEMBELAJARAN SENI TARI
Authors: Catur Harist Harjanti , Sunarto Sunarto - , Lestari Wahyu -
Published: July 2022

Kurangnya minat peserta didik laki-laki dalam mengikuti pembelajaran seni membuat proses belajar mengajar menjadi tidak efektif. Masalah yang diambil yaitu peningkatan minat peserta didik laki laki dalam pembelajaran seni tari. Tujuan pembelajaran adalah untuk mengetahui proses pembelajaran model inkuiri. Manfaat pembelajaran dapat diajukan untuk acuan pembelajaran model inkuiri. Metode yang digunakan adalah kualitatif dan R&D. Teknik pengumpulan data menggunakan observasi, wawancara, dan dokumentasi. Teknik validasi data menggunakan metode triangulasi. Teknik analisis data yang digunakan adalah reduksi data, penyajian ulang, dan penarikan kesimpulan. Berdasarkan enam tahap proses pembelajaran inkuiri peserta didik laki-laki pada awalnya tidak tertarik dengan tarian dan hanya diam saja pada saat pembelajaran seni tari, dengan diterapkannya model inkuiri siswa menjadi lebih aktif dan terlibat berkontribusi pada pembelajaran di kelas. Saran untuk lebih memperhatikan waktu selama penyampain  karena membutuhkan waktu yang lama agar materi yang lain juga tersampaikan sesuai rencana.
Universal-Diverse Orientation Promotes Congruent Ethnic and National Identities: A Preliminary Research Note
Authors: Burhan Omar Khalifa , Nauly Meutia , Purba Ridhoi Meilona , Sinulingga Rahma F. , Irmawati
Published: July 2022

The present study conceptualizes “Unity in Diversity” as a condition in which individuals’ ethnic and national identities are congruent. This condition is achievable by internalizing universal-diverse orientation. The authors provide support for this idea through a cross-sectional survey (N = 400), and observed a positive relationship between individuals’ ethnic and national identities among individuals with high universal-diverse orientation. Such a relationship was absent among individuals with low universal-diverse orientation. Based on the results, the authors recommend socializing universal-diverse orientation to promote a sense of “Unity in Diversity” among individuals within a multicultural society, such as that of Indonesia.

Studi ini mengonseptualisasi “Bhinneka Tunggal Ika” sebagai kondisi ketika terdapat keselarasan identitas suku bangsa dan nasional seorang individu. Kondisi ini bisa dicapai melalui internalisasi universal-diverse orientation. Penulis menyediakan data yang mendukung konsep ini melalui survei cross-sectional (N = 400), dan menemukan hubungan positif antara identitas suku bangsa dan identitas nasional pada individu dengan universal-diverse orientation tinggi. Hubungan ini tidak ditemukan pada individu dengan universal-diverse orientation rendah. Berdasarkan temuan ini, penulis merekomendasikan upaya sosialisasi universal-diverse orientation untuk menguatkan rasa “Bhinneka Tunggal Ika” pada individu dalam masyarakat multikultur layaknya Indonesia.
Sintasan Pasca Penangkapan Hasil Tangkapan Perikanan Glass Eels Di Estuari Sungai Cikaso, Sukabumi
Authors: Annida Shafira Bilqis , Zulkarnain Zulkarnain , Wahju Ronny Irawan , Simanjuntak Charles P.H. , Purbayanto Ari
Published: July 2022

Estuari Sungai Cikaso merupakan satu di antara beberapa daerah penangkapan glass eels dengan hasil tangkapan tertinggi di Kabupaten Sukabumi, Jawa Barat. Usaha perikanan tangkap glass eels pada dasarnya dilakukan untuk memenuhi pasokan benih untuk kegiatan pembesaran ikan sidat. Nelayan menggunakan dua alat dalam melakukan penangkapan glass eels yaitu bubu dan sirib. Terdapat perbedaan konstruksi dan teknis pengoperasian kedua alat tangkap ini, yang mengindikasikan adanya perbedaan tingkat stres yang dialami oleh ikan hasil tangkapan. Tingkat stres pasca penangkapan akan berujung pada rendahnya sintasan dan kualitas benih untuk kegiatan pembesaran ikan sidat. Kajian mengenai kelangsungan hidup pasca penangkapan ini sangat penting untuk diketahui karena berkaitan dengan penilaian alat tangkap. Penelitian bertujuan untuk mengetahui tingkat kelangsungan hidup pasca penangkapan terhadap hasil tangkapan alat tangkap bubu dan sirib dilakukan setiap bulan dari Februari hingga April 2021. Ikan yang tertangkap dipelihara dalam akuarium selama empat hari pengamatan pasca penangkapannya. Terdapat perbedaan sintasan glass eels yang tertangkap dengan dua alat tangkap yang berbeda. Tingkat kelangsungan hidup glass eels pada alat tangkap bubu (~63%) lebih rendah dibandingkan dengan alat tangkap sirib (~68%). Hal serupa juga ditemukan pada ikan hasil tangkapan sampingan untuk kedua alat tangkap tersebut. Ikan hasil tangkapan sampingan yang tertangkap dengan bubu umumnya memiliki luka pada beberapa bagian tubuhnya, sedangkan ikan tangkapan sampingan yang tertangkap dengan sirib umumnya tanpa luka pasca penangkapan. Tingkat kematian ikan pasca penangkapan berkaitan erat dengan persentase luka yang dialami oleh ikan.
Desain Media Pengangkut Ikan Hias Untuk Skala Kecil (Studi Kasus Di Padang Panjang)
Authors: Novita Yopi , Nadira Annisa Luklu , Yuwandana Dwi Putra , Bangun Tri Nanda Citra
Published: July 2022

Transportasi ikan hias di Kota Padang Panjang Sumatera Barat menggunakan kendaraan bermotor, dimana wadah transportasi berupa anyaman bambu berbentuk silinder dengan ketinggian 30 cm diletakkan di sisi kiri dan kanan motor. Ikan hias dan air yang melengkapinya, ditempatkan dalam wadah transportasi. Muatan berupa ikan dan air termasuk jenis muatan liquid.  Muatan liquid akan menimbulkan efek free surface yang membahayakan ikan dan pengendara, dikarenakan muatan liquid akan bergerak selama wadah yang ditempatinya bergerak. Penelitian ini bertujuan untuk meredesain wadah pengangkut ikan hidup dan membandingkannya dengan wadah pengangkut sebelumnya terkait dengan kemampuannya untuk meredam pergerakan muatan liquid.  Selain itu, redesain wadah dimaksudkan untuk meningkatkan survival rate ikan.  Penelitian dilakukan secara eksperimental untuk mendapatkan karakteristik pergerakan free surface, kondisi kualitas air di dalam wadah, dan survival rate ikan. Analisis data dilakukan dengan cara komparatif numerik dan uji statistik menggunakan Rancangan Acak Lengkap (RAL). Redesain wadah transportasi dilakukan dengan menambahkan sirip peredam di bagian dalam wadah, dan dipasang tepat pada garis air, serta dilengkapi dengan penutup di bagian atas wadah.  Sirip peredam digunakan untuk meredam pergerakan free surface, sedangkan penutup di bagian atas wadah didesain agar air hujan atau sinar matahari tidak langsung masuk ke dalam wadah.  Selain itu, desain penutup wadah didesain agar aliran udara tetap bisa keluar masuk ke dalam wadah.  Hasil eksperimen menunjukkan wadah hasil redesain mampu mengurangi kemiringan permukaan air di dalam wadah transportasi hingga 50% lebih rendah dibandingkan dengan wadah sebelum diredesain.  Selain itu, wadah hasil redesain mampu menghasillkan nilai survival rate ikan mencapai 99,83% atau kematian ikan 0-1 ekor per perjalanan.
Multidisciplinar: Os Desafios para o Crescimento Profissional
Authors: Santos Maia Luiz Faustino dos
Published: July 2022

O profissional de enfermagem é uma dádiva de Deus na vida daqueles que precisam de sua dedicação que levanta o ânimo, transmite paz, alegra o coração e faz a diferença. Em maio comemoramos a semana da enfermagem e há no trabalho da enfermagem três principais elementos, considerados básicos em nossos dias: espírito de serviço, habilidade e ciência. Portanto parabenizamos a todos profissionais de enfermagem que dedicam suas vidas a cuidar de outra pessoa, seja na teoria ou na prática.
Prezados Colegas
Authors: Montosa da Fonseca Selma
Published: July 2022

A Enfermagem Brasileira entrou no novo século acompanhando as transformações que vêm ocorrendo no processo histórico mundial. Percebe-se a diversidade de temas publicados por profissionais e estudantes de enfermagem em diversas revistas. Todos os dias novos equipamentos e formas revolucionárias de tratamento passam a fazer parte da vida do profissional de saúde, numa velocidade incontestável e o conhecimento de avanços nos campos científicos e tecnológicos, precisam estar atualizados.
Humanização em unidade de terapia intensiva: a enfermagem e o cuidado humanizado
Authors: Santos Maia Luiz Faustino dos
Published: July 2022

Humanizar é retomar o respeito à vida humana, considerando todos os aspectos adjacentes em sua existência. Especialmente na unidade de terapia intensiva, um local culturalmente desconhecido e incerto aos pacientes e familiares. Trata-se de um estudo de revisão bibliográfica, com objetivo de enfatizar os aspectos sobre humanização no ambiente de unidade de terapia intensiva a enfermagem e o cuidado humanizado. Identificou-se que os cuidados intensivos são desafiadores, pois assistir o ser humano numa visão holística requer aliar aos conhecimentos técnicos e científicos, comunicação e empatia, promovendo e estreitando as relações humanas.
Câncer de mama: a mulher e os sentimentos em questão
Authors: Barbosa Ana Cristina Maciel , Brabosa Márcia , Silva Janize Carlos da , Zapparoli Trandafilov Amanda
Published: July 2022

O câncer de mama é provavelmente o mais temido pelas mulheres, devido à sua alta frequência, e, sobretudo, por acometer uma parte tão valorizada do seu corpo, associada às imagens de intimidade, oferenda, dádiva e refúgio. De acordo com o Instituto Nacional do Câncer, representa a principal causa de morte entre as mulheres. Este estudo teve como o objetivo identificar os sentimentos vivenciados pela mulher após o diagnóstico do câncer de mama, uma doença, quase sempre associada ao estigma de morte. Utilizou-se a revisão de literatura como método. As bases LILACS, SciELO, BIREME, e livros sobre a temática foram utilizados para o processo de coleta de dados. O estudo possibilitou compreender que a confirmação do diagnóstico desencadeia um processo de conflitos, ocorrendo uma mescla de sentimentos. Para uma assistência qualificada, portanto, os profissionais de enfermagem devem considerar estes sentimentos dando a oportunidade para que a mulher adote uma postura positiva, buscando recursos de fortalecimento para o seu enfrentamento.
O enfermeiro no gerenciamento de resíduos dos serviços de saúde
Authors: Batista do Nascimento Eliane , Santos Maia Luiz Faustino dos
Published: July 2022

O gerenciamento dos resíduos de serviços de saúde são desafios para a comunidade, principalmente para os órgãos geradores desses resíduos, pois compete ao gerador minimizar o transtorno e gerenciá-lo adequadamente. Devido aos agentes biológicos patogênicos e toxidade que geralmente os acompanham, oferecem riscos à saúde humana e ao meio ambiente, por isso exigem especial atenção e responsabilidade de seus geradores e do poder público. O enfermeiro é um profissional que tem importante papel neste contexto, atuando num constante processo educativo e de conscientização, para que se estabeleçam as melhores práticas de gestão nessa área, tendo capacidade técnico científica para o gerenciamento dos resíduos de saúde. Assim esta pesquisa objetivou identificar e conhecer o enfermeiro no gerenciamento de resíduos dos serviços de saúde. Os resultados mostram que o enfermeiro precisa ter olhar crítico, detectar os problemas e solucioná-los, ganhar credibilidade, alcançar a segurança e proteção do cliente e da equipe.
Cuidados de enfermagem a criança com câncer: uma breve revisão bibliográfica
Authors: Ribeiro Soriano Nilson , Santos Maia Luiz Faustino dos
Published: July 2022

No Brasil, o câncer infantil atinge mais de cinco mil crianças, levando a mais de dois mil óbitos por ano. O aumento progressivo do número de casos de crianças com câncer tem despertado muitos profissionais da saúde para a realização de pesquisas que contribuam para uma assistência de qualidade para essa clientela e seus familiares. Este estudo consistiu-se de uma pesquisa de revisão bibliográfica de natureza exploratória, direcionada ao cuidar em enfermagem. A assistência de enfermagem a crianças com câncer deve ser holística, mesmo sabendo das dificuldades na sua implementação. Os cuidadores necessitam de recursos de apoio e segurança, revisão de seus conhecimentos sobre a doença e atividades de enfermagem nesta área e ainda tenham informações sobre a evolução de crianças que cuidaram, minimizando sentimentos negativos, reduzindo incertezas sobre a efetividade do tratamento, levando-os a oferecer um cuidado otimizado e humanizado.
Saúde do idoso, o envelhecimento e as políticas públicas de saúde
Authors: Mello de Souza Thaís , Santos Maia Luiz Faustino dos
Published: July 2022

Desde os anos sessenta do século passado, a expressão qualidade de vida tem sido referência de inúmeros discursos acadêmicos, políticos, ideológicos. A preocupação com a saúde do idoso vem promovendo a implantação de políticas públicas de saúde, visando cada vez mais melhoria da qualidade de vida. O envelhecimento populacional é um fenômeno que diz respeito a todos, não ficando circunscrito apenas aos cidadãos maiores de 60 anos. Portanto esta pesquisa através de uma revisão literária objetivou levar ao conhecimento dos profissionais de saúde a cerca da saúde do idoso e as políticas públicas de saúde para este segmento etário. Os resultados mostrou que os profissionais de saúde têm uma grande importância para a melhoria, implementação e execução das políticas públicas de saúde.
The Influence of Aflatoxin B1 on the Concentration of Nuclear Factor κB in Rats’ Livers
Authors: Woźniakowski Mateusz , Woźniakowska Nikola , Zuzak Tomasz , Świerszcz Łukasz , Wójciak-Czuła Marta , Borzęcki Andrzej , Nieradko-Iwanicka Barbara
Published: July 2022

Introduction. Aflatoxins are metabolites produced by Aspergillus flavus and Aspergillus parasiticus. Due to the high prevalence of aflatoxin-containing products they are common issue of the observational studies. Observational studies have demonstrated the hepatotoxic effects of aflatoxins in humans. However, the exact pathogenetic mechanisms of the effect of aflatoxin B1 on the above-mentioned hepatotoxicity have not yet been known.

Aim of the study. The aim of the study was to assess the toxic effects of different doses of aflatoxin B1. The analyze was performed using assessment of concentration of NF-κB in liver tissue homogenates after a 7-day intoxication with this mycotoxin.

Material and methods. The studies were carried out on Wistar male rats which were selected randomly, according to the principle of simultaneity for the control group and the study groups. The concentration of NK-κB was determined by immunoenzymatic ELISA in the obtained supernatants of liver taken from decapitated animals. The statistical analysis was performed with Statistica 13.3 (Statsoft, USA).

Results. The statistical significance of the difference between the concentrations in the control and study group receiving 1.0 mg/kg of aflatoxin B1 and between the control and study group who received aflatoxin B1 at a dose of 2.0 mg/kg body weight (p <0,05) were demonstrated. A significant relationship was also found between the level of dose of aflatoxin B1 administered to the rats and the concentration of NF-κB. Negative correlations were obtained. The higher dose administered to rats - the lower level of measured concentration of NF-κB.

Conclusions. The study of the influence of aflatoxin B1 on the level of NF-κB transcription factor may significantly contribute to understand the mechanism of its action, influence on inflammatory, apoptotic and carcinogenic processes in the liver and determine its safe level in food intended for humans and animals.
Dampak Pandemi Covid-19 dan Strategi Pengembangan Terhadap Desa Wisata Telaga Biru Cigaru Kabupaten Tangerang
Authors: Rechtta Utami Nadya , Yuniati Nining , Soeroso Amiluhur
Published: July 2022

Cigaru Blue Lake Rural Tourism is located in Cigaru Village, Cisoka Village, approximately 10 kilometers from the Tangerang Regency Government Headquarters. The attraction of this destination is a distinctive culture and lake that has blue water colour, the lake is not a natural tourism but artificial tourism, the destination has become famous and can become a tourist village in the Cisoka area, Tangerang because it has inclusion from the Cigaru Village government. and supervised by the local community and there is authority as the headman. it has problems, first, related to visits in recent times, visits have decreased even if there are no visitors. Second, several facilities were damaged, there was no cost to renovate, thus hampering its development. The method used is a qualitative case study and the technique used is descriptive. The conclusions from this study were concluded based on the formulation of the existing problems and the results were: The impact of the pandemic on the Cigaru Blue Lake Rural Tourism, namely the decrease in tourist visits that occurred resulting in a decrease in the economic level experienced by the people of Cigaru Village, then the CHSE protocol had not been implemented so that the destination has not been able to operate again. In addition, researchers found other problems outside of the impact of the pandemic, namely the ineffectiveness of the concept of a rural tourist in the destination so that the right strategy was needed to draw conclusions in strategic planning, then the development strategy needed in the Cigaru Blue Lake Rural Tourism, namely by implementing CHSE and developing on facilities and activities (Eco-Lodge, Eco-Recreation and Eco-Education) at Cigaru Blue Lake Rural Tourism.

Keywords: rural tourism, cigaru blue lake, development strategy, pandemic, covid-19.
Patient Satisfaction with Professional Continuous Glucose Monitoring in a Diverse Family Medicine Clinic: A Pilot Study
Authors: Hougas, III James E. , Nichol Heidi R. , Montag Schafer Katherine
Published: July 2022

Primary care providers (PCPs) manage a large portion of patients with diabetes. Continuous glucose monitoring (CGM) can give detailed information about glucose trends to improve treatment and safety. We conducted a prospective cohort pilot study to understand patient experience with the use of professional CGM in a primary care practice with a high volume of diverse, non-English speakers. Eligible patients were on an insulin regimen and either had an A1c above goal or whose PCPs had concerns for hypoglycemia. Surveys were collected prior to the intervention to assess the acceptability of the patient's self-monitoring blood glucose efforts and after the intervention to assess their experience of using the CGM. Participants at baseline had a mean A1c of 10.6% and a high amount of emotional distress as measured on the Problem Areas in Diabetes (PAID) scale. Post-intervention, patients reported their experience with professional CGM was positive and, overall, as acceptable of an intervention as their previous self-monitoring blood glucose practice. Professional CGM can serve as an additional, acceptable tool for PCPs to better understand how to help patients achieve diabetes blood glucose goals. Ambulatory care pharmacists are well positioned to lead this effort in clinics.
تنفيذ طريقة التسميع الفردي في تحفيظ القرآن لطلبة قسم التفسير وعلوم القرآن
Authors: Siregar Oktaviani
Published: July 2022

ولكلمة  الحفظ مشتاقة من: حفظ - يحفظ وتعني الحراسة والحفظ، وتحفيظ القرآن عمل نبيل يقوم به المسلمون، وينشط فيه الحافظون في حراسة كل كلمة في القرآن. حفظ القرآن دائماً قريب من الله، لأنهم يتفاعلون دائماً من خلال القراءات التي يقرؤونها كل يوم، حفظ القرآن نشاط يمكن أن يحافظ على عظمة القرآن. إن حفظ القرآن معجز أعطاها الله لكل من اختار أن يحفظه لأن القرآن كثيف، وكثير من السور والآيات لا تثني الناس عن حفظه.في حفظ القرآن فوائد كثيرة يجنيها الحفظون، وذلك لما يُمنح من امتيازات كثيرة لحفظة القرآن، ومنها أن حفظة القرآن هم آل الله سبحان الله وتعالى ورد حديث النبي محمد صلى الله عليه وسلم. أهْلُ القرآن أهل لله. الطريقة المعنية هي طريقة منهجية ومدروسة جيدًا لتحقيق الهدف. في هذه الحالة الطريقة التي يستخدمها الطلاب في حفظ القرآن. تسميع هو الاستماع إلى الحفظ للآخرين. في هذه الحالة، يمكن للطلاب الاستماع إلى حفظهم للأصدقاء أو المشرف عليهم.الفرد هو نشاط فردي بمعنى الكلمة عندما تكون عملية الحفظ هي الحفظ فقط مع تفاعل المشرف. هذا النوع من البحث هوالبحث الميداني. "الميداني" (البحث الميداني) في الإثنوغرافيا يعني أن الباحث يجمع البيانات في البيئة التي يوجد فيها المشترك وحيث يمكن دراسة الأنماط الثقافية.  أي بالتحليل من خلال وصف ووصف محتويات البيانات التي يحصل عليها المؤلفون، ثم الربط مع المشكلات المطروحة بحيث يتم العثور على استنتاجات موضوعية ومنطقية ومتسقة ومنهجية وذلك وفقا للأهداف المنشودة في كتابة الرسالة.لذا فإن الاستنتاج من هذه الدراسة هو أن تطبيق التسميع الفردي في حفظ القرآن لطلبة علوم القرآن والتفسير يسير بشكل جيد عند الاطلاع عليه من بيانات الطالب، وقد وصل بعضها إلى الهدف، فقط أن النواقص في هذه الطريقة هي في الطلاب الذين هم أقل قدرة على تحقيق هدف الحفظ وفي زمان ومكان لا يفضيان إلى إجراء دورات تحفيظ.
Lethal encephalitis in a pediatric patient with SARS-CoV-2
Authors: Yimenicioğlu Sevgi , Zararcı Kazım , Aynacı Ali Murat , Yılmaz Ayşe Tekin
Published: July 2022

Background. SARS-CoV-2 mostly affects the respiratory system. Some studies have reported neurological disorders associated with SARS-CoV-2. Despite an increase in reported instances, encephalitis caused by COVID-19 infection is still poorly understood.
Case. We reported a rare presentation of SARS-CoV-2 in a 15-year-old patient. He had a fulminant course with encephalitis. He had mild symptoms of a COVID-19 infection five months ago and recovered without any sequel. Despite appropriate treatment, the patient had a devastating course.
Conclusions. This was a severe presentation of SARS-CoV-2 with central nervous system manifestations.
Difficulties in the diagnosis and management of eight infants with secondary pseudohypoaldosteronism
Authors: Günay Fatih , Şıklar Zeynep , Berberoğlu Merih
Published: July 2022

Background. Type 1 pseudohypoaldosteronism (PHA1) is a rare condition characterized by the resistance of the kidney to the effect of aldosterone. Secondary PHA1 is a syndrome that is most often related to urinary tract anomalies (UTAs) and/or urinary tract infections (UTIs). A similar pattern of electrolyte impairment is seen in congenital adrenal hyperplasia (CAH) and secondary PHA1, and CAH is a condition that requires urgent treatment. In our study, eight patients aged between 15 days and 8 months (seven males and one female) were included in the evaluation. It was aimed to evaluate cases of secondary PHA1 in our clinic and to identify the problems encountered in diagnosis and follow-up.
Methods. The records of the patients who presented to our hospital between February 2010 and 2021 were retrieved and retrospectively scanned.
Results. In all cases, hyponatremia, hyperkalemia, hyperaldosteronism, and hyperreninemia were detected. Other biochemical and hormonal tests were normal. Leukocytosis was detected in urine analysis, and urine cultures were productive. UTA was detected in five cases. Nine episodes of PHA1 occurred in eight patients and fungal infections were responsible for causing two episodes. Four episodes of PHA1 needed mineralocorticoid treatment. On the third day, serum electrolytes normalized. Fludrocortisone treatment was continued for 1 week. In one case, UTIs were repeated with PHA1, but in the follow-up, there were no additional problems.
Conclusions. Secondary PHA1 should be kept in mind when hyponatremia and hyperkalemia are seen, especially in infants aged under 3 months or older, up to 8 months, who present with non-specific symptoms. Fungal infections should not be forgotten in UTI etiology because PHA1 episodes can be initiated. If CAH is suspected, mineralocorticoid treatment should be rapidly initiated.
Autosomal recessive hypophosphatemic rickets type 2; a novel mutation in the ENPP1 gene
Authors: Bitkin Eda Çelebi , Aymelek Huri Sema
Published: July 2022

Background. Hypophosphatemic rickets (HR) is a rare disease caused by several genetic mutations in factors that cause an increase in fibroblast growth factor 23 (FGF23), and renal phosphate transporters. ENPP1 (ectonucleotide pyrophosphatase / phosphodiesterase 1) mutations cause autosomal recessive inheritance hypophosphatemic rickets type 2.
Case. In our study, we present a novel mutation in the ENPP1 gene detected in 4 siblings in a single family.
Conclusion. Our findings can be applied to further understand molecular pathogenesis and to establish a correlation between genotype and phenotype for HR.
The Benefits of Adding Manual Therapy to Exercise Therapy for Improving Pain and Function in Patients With Knee or Hip Osteoarthritis: A Systematic Review With Meta-analysis
Authors: Runge Nils , Aina Alessandro , May Stephen
Published: July 2022

OBJECTIVE: To evaluate if there was an additional benefit of combining manual therapy (MT) and exercise therapy over exercise therapy alone on pain and function in patients with hip or knee osteoarthritis.

DESIGN: Intervention systematic review

LITERATURE SEARCH: We (1) searched 4 databases from inception to June 20, 2021; (2) hand searched a reference list of included trials and relevant systematic reviews; and (3) contacted 2 researchers in the field.

STUDY SELECTION CRITERIA: We included randomized controlled trials that compared MT and exercise therapy to similar exercise therapy programs alone in patients with hip or knee osteoarthritis.

DATA SYNTHESIS: The data were combined using random-effects meta-analyses where appropriate. The certainty of evidence for each outcome was judged using the Grading of Recommendations, Assessment, Development, and Evaluations (GRADE) framework.

RESULTS: We included 19 trials. There was very low to moderate certainty of evidence that MT added benefit in the short term for pain, and combined pain, function, and stiffness (WOMAC global scale), but not for performance-based function and self-reported function. In the medium term, there was low- to very-low-certainty evidence that MT added benefit for performance-based function and WOMAC global score, but not for pain. There was high-certainty evidence that MT provided no added benefit in the long term for pain and function.

CONCLUSION: There was very low to moderate certainty of evidence supporting MT as an adjunct to exercise therapy for pain and WOMAC global scale, but not function in patients with knee or hip osteoarthritis in the short term. There was high certainty of evidence of no benefit for additional MT over exercise therapy alone in the long term. J Orthop Sports Phys Ther 2022;52(10):675–684. Epub: 27 July 2022. doi:10.2519/jospt.2022.11062
Diagnosing, Managing, and Supporting Return to Work of Adults With Rotator Cuff Disorders: Clinical Practice Guideline Methods
Authors: Dyer Joseph-Omer , Doiron-Cadrin Patrick , Lafrance Simon , Roy Jean-Sébastien , Frémont Pierre , Dionne Clermont E. , MacDermid Joy C. , Tousignant Michel , Rochette Annie , Lowry Véronique , Saulnier Marie , Vukobrat Tatiana , Desmeules François
Published: July 2022

OBJECTIVES: To present the methods used to develop a clinical practice guideline (CPG) with recommendations endorsed by key stakeholders for assessing, managing, and supporting return to work for adults with rotator cuff disorders.

DESIGN: Clinical practice guideline development.

METHODS: A steering committee composed of the research team of this project led the development of this CPG in 5 phases, which followed the standards of the NICE and AGREE II collaborations. During the preparation phase (I), a multidisciplinary working committee of experts in managing rotator cuff disorders (n = 20) determined the scope and objectives of the CPG. The recommendations development phase (II) included initial knowledge synthesis, development of preliminary recommendations, systematic consultations with a multidisciplinary panel of key stakeholders (n = 51) using a modified three-round Delphi approach and drafting of the original CPG. In the external evaluation phase (III), an external committee of experts evaluated the original CPG using the AGREE II tool. In the dissemination phase (IV), the strategy for disseminating the CPG was developed and implemented. During the update phase (V), the CPG was revised based on an update of the initial knowledge synthesis.

RESULTS: Seventy-three preliminary recommendations were developed from the initial knowledge synthesis. During the Delphi consultation, all of these recommendations were endorsed, and one new recommendation was proposed by panelists. The original CPG received an overall AGREE II score of 83% from the external evaluators. In 2021, an update of the initial 2017 knowledge synthesis was conducted and 13 recommendations were revised.

CONCLUSION: The 5-phase consensus methods approach guided the development of a high-quality CPG on assessing, managing, and supporting return to work for adults with rotator cuff disorders. J Orthop Sports Phys Ther 2022;52(10):665–674. Epub: 27 July 2022. doi:10.2519/jospt.2022.11307
BIST’e Kayıtlı Ulaştırma ve Depolama Sektöründe Faaliyet Gösteren Şirketlerin Finansal Performanslarının Analitik Hiyerarşi Süreci (AHS) ve Gri İlişkisel Analiz (GİA) Yöntemleriyle Değerlendirilmesi
Authors: SAKARYA Şakir , SAÇKES İlyas
Published: July 2022

Çalışma, BİST' XULAS endeksinde işlem gören, Ulaştırma ve Depolama Sektöründeki 8 işletmenin, karlılık odaklı finansal performansını, AHS bütünleşik GİA yöntemi ile analiz ederek, covid-19 sürecindeki değişimlerini incelemek ve işletmelerin, karlılık odaklı bir finansal performans sıralamasını elde etmeyi amaçlamaktadır. Bu kapsamda işletmelerin 2018-2020 dönemi mali tablolarına ait 15 adet nakit esaslı finansal oran “finansal performans kriteri” olarak kabul edilmiştir. AHS ile kriterlerin hiyerarşik yapısı oluşturulduktan sonra, elde edilen kriterlerin ağırlıkları kullanılarak GİA yöntemi ile beher yıl için finansal performans sıralaması elde edilmiştir. Bulgulara göre TLMAN en iyi finansal performansı göstermiştir. Sıralamada THYAO ise son sırada yer almıştır.
Description of the Rite of Approval of the Kazakh Khan Nuraly in 1749
Authors: Lapin N. S.
Published: July 2022

The article considers the confirmation of the Kazakh khans as the subjects of the Russian Empire. The implementation of the confirmation institute has become a new tool of Russia’s influence on the Kazakh elite. The publication allows us to imagine how Russian border officials tried to introduce new mechanisms of control over the Kazakhs. The lack of military and political resources forced Russian administrators to use symbolic resources in their relations with the Kazakhs. One of these, along with the oath, was the confirmation of the Kazakh ruler by the khan, made on behalf of the Russian ruling monarch. The first experience was the confirmation of the khan's dignity of Sultan Nuraly, the son of the elder khan of the Kazakhs, Abulkhair, who died in 1748. Nuraly’s statement became a precedent in relations with the Kazakhs. Russian authorities approved the Kazakh khan in July 1749; the first ceremony in the history of Kazakh-Russian relations took place near Orenburg. The Orenburg governor I. I. Neplyuev developed the rite of confirmation in detail. The ceremony included the arrival of Nuraly to the place of confirmation, the meeting of the khan, the announcement of his khan, the oath, the presentation of royal gifts, an official dinner with the participation of the approved khan, his entourage and Orenburg officials and military, and a number of other circumstances.