bluuebunny/crossref_metadata_2025 huggingface dataset:
Clinical findings and outcomes for dogs with uveodermatologic syndrome
Authors: Zarfoss Mitzi K. , Tusler Charlotte A. , Kass Philip H. , Montgomery Keith , Lim Christine C. , Mowat Freya , Thomasy Sara M.
Published: April 2018

OBJECTIVE To evaluate signalment, clinical signs, treatment, and factors affecting visual prognosis in dogs with uveodermatologic syndrome (UDS).

DESIGN Retrospective case series and nested cohort study.

ANIMALS 50 dogs (37 Akitas and 13 non-Akitas) with UDS evaluated at 4 ophthalmology practices.

PROCEDURES Data were collected from the medical records regarding signalment, clinical signs, biopsy results, medications, adverse effects, vision and glaucoma status at initial and subsequent examinations, and duration of follow-up. Various factors were examined for associations with development of blindness or glaucoma following initial examination.

RESULTS The most common ophthalmic signs included aqueous flare (n = 35 [70%]), iris abnormalities (29 [58%]), retinal detachment (23 [46%]), and choroidal depigmentation or chorioretinal infiltrates (10 [20%]). At initial examination, 36% (18/50) of dogs had glaucoma and 57% (26/46) were blind in both eyes. Twenty-five (50%) dogs had vision at their final visit, representing 78% of the 32 dogs that had vision at initial examination or regained vision during the follow-up period. In dogs that lost vision, median time to permanent blindness in both eyes was 13.5 months (range, 0.4 to 59 months) after initial examination. No significant associations with time to glaucoma or vision loss were identified for signalment variables, specific medications, or duration of clinical signs prior to initial examination.

CONCLUSIONS AND CLINICAL RELEVANCE UDS commonly resulted in glaucoma, vision loss, or both in affected dogs. No evaluated factor was associated with visual prognosis; however, a subset of patients maintained vision through to the final recheck examination.
Effect of lemongrass water extract supplementation on atherogenic index and antioxidant status in rats
Authors: Somparn Nuntiya , Saenthaweeuk Suphaket , Naowaboot Jarinyaporn , Thaeomor Atcharaporn , Kukongviriyapan Veerapol
Published: April 2018

Cymbopogon citratus (DC) Stapf., commonly known as lemongrass, possesses strong antioxidant and cardiotonic properties. Lemongrass water extract contains several polyphenolic compounds including gallic acid, isoquercetin, quercetin, rutin, catechin and tannic acid. Rutin, isoquercetin catechin and quercetin are the flavonoids most abundantly found in the extract. The extract significantly decreased total cholesterol, low-density lipoprotein and atherogenic index in rats after treatment (p < 0.05). Expression of genes and protein of sterol regulatory element binding protein-1c (SREBP1c) and HMG-CoA reductase (HMGR) was also lowered significantly in treated groups (p < 0.05). Moreover, serum antioxidant capacity increased in treated rats in comparison with untreated ones (p < 0.05) and was associated with decreased serum lipid peroxidation.
Advocacy Coalitions in Transport Policy: A Case of Rail Sector in Croatia
Authors: Poljak Željko
Published: April 2018

The author analyses the transport policy of the rail sector in Croatia and tries to give answers regarding the policy stability and change based on the actors in the rail transport. The aim of the paper is to give an overview of the development of the rail sector in modern Croatia and to explore, in a larger period, the relations and beliefs of all types of actors in this area at the national level. As a theoretical background, the author uses an advocacy coalition framework, which states that policy actors are grouped into coalitions within a policy subsystem in which they advocate their beliefs in order to transfer them into government programs, thus provoking change and stability in the system. The author methodologically uses qualitative content analysis in the form of coding of the collected material based on transcripts of interviews with actors, official documents, and transcript of one parliamentary debate. Following is a review of the historical development of the rail sector in Croatia, with an emphasis on the post-independence Croatia period, which provides a basis for concrete research findings. The results are presented in two units: (1) identified actors and their relations, and (2) beliefs of actors. The follow-up discussion points to the existence of similar patterns of beliefs among the actors at the national level. However, the empirical material collected does not establish clear relationships that could be classified as an advocacy coalition. In conclusion, the author argues that the coded material does not give away any importance of the coalitions of actors at the national level for policy stability and change of rail sector leading to recommendations for further research in this area, where other transport sectors should be included as well as international actors.
Prevalence, abundance and intensity of eggs and oocysts of gastrointestinal parasites in the opossum Didelphis virginiana Kerr, 1792 in Yucatan, Mexico
Authors: Aragón-Pech R. A. , Ruiz-Piña H. A. , Rodríguez-Vivas R. I. , Cuxim-Koyoc A. D. , Reyes-Novelo E.
Published: April 2018

Virginia opossum, Didelphis virginiana, is a synanthropic mammal associated with peridomestic areas of Yucatán, However, little is known about the gastrointestinal parasite infections of this species. The infection prevalence, mean abundance and mean intensity of eggs and oocysts of gastrointestinal parasites, in opossums captured in the peridomestic areas were estimated in six rural localities of Yucatán, Mexico. Eighty-four faecal samples were processed by flotation technique. McMaster test was used to estimate the number of helminth eggs and protozoa oocysts per gram of feces. Seven genera of gastrointestinal parasites were identified, and then infection prevalence was estimated as follows: Protozoa Eimeria sp. (51.9 %) and Sarcocystis sp. (1 %); nematodes Ancylostoma sp. (80.56 %), Cruzia sp. (62.04 %), Trichuris sp. (60.19 %), Capillaria sp. (29.63 %), Turgida sp. (23.15 %), Toxocara sp. (11.11 %), and Ascaris sp. (1.85 %); and one acanthocephalan: Oligacanthorhynchus sp. (14.81 %). This is the first study on the diversity of gastrointestinal parasites in Virginia opossums, and first evidence about the potential role of opossums in the transmission of zoonotic gastrointestinal parasites in peridomestic areas of Yucatán, Mexico.
The anti-parasitic effect of probiotic bacteria via limiting the fecundity of Trichinella spiralis female adults
Authors: Bucková B. , Hurníková Z. , Lauková A. , Revajová V. , Dvorožňáková E.
Published: April 2018

A potential protective effect of probiotic strains against zoonotic Trichinella spiralis infection was investigated in the framework of a new therapeutic strategy aimed at using probiotics to control parasitic zoonoses. The study was focused on the impact of six selected probiotic (bacteriocinogenic) strains on the intensity of T. spiralis infection and female fecundity ex vivo and in vitro. Bacterial strains of different origin (Enterococcus faecium EF55, Enterococcus faecium 2019 = CCM7420, Enterococcus faecium AL41 = CCM8558, Enterococcus durans ED26E/7, Lactobacillus fermentum AD1 = CCM7421, Lactobacillus plantarum 17L/1) were administered daily in a dose of 109 CFU/ml in 100 μl, and mice were infected with 400 T. spiralis larvae on day 7 of treatment. Female adults of T. spiralis were isolated on day 5 post infection (p.i.) and subsequently were used in fecundity test ex vivo. E. faecium CCM8558, E. faecium CCM7420 and E. durans ED26E/7 strains significantly reduced the number of adults in the intestine. The application of L. fermentum CCM7421, L. plantarum 17L/1, E. faecium CCM8558 and E. durans ED26E/7 caused a significant decrease in the number of muscle larvae. The treatment with E. faecium CCM8558 and E. durans ED26E/7 showed the highest inhibitory effect on female fecundity (94 %). The number of newborn larvae (NBL) was also significantly decreased after administration of L. fermentum CCM7421 and L. plantarum 17L/1 (80 %). A direct impact of probiotic strains on female reproductive capacity was examined in vitro in females isolated from untreated infected mice on day 5 p.i. A correlation was found between the inhibitory effect and the concentration of probiotic strains. The reduction effects of the strains manifested as follows: L. fermentum CCM7421 (93 %), E. faecium CCM8558, L. plantarum 17L/1, E. faecium EF55 (about 80 %), E. faecium CCM7420 and E. durans ED26E/7 (about 60 %).
The geochemical and isotopic carbon cycle in an urban pond in the City of Wroclaw
Authors: Drzewicki Wojciech , Kościukiewicz Pola , Trojanowska-Olichwer Adriana
Published: April 2018

The aim of this study was a recognition of the carbon cycle in a small anthropogenic reservoir located in Wrocław (SW Poland). The research investigated the geochemical processes and isotopic interactions in the water column as well as those between the water column and the sediment. Moreover, an attempt was made to identify the sources of carbon in the studied water body. Observations of temporal and spatial (vertical and horizontal) geochemical trends were the subject of this research. Chemical and isotopic analyses were the main tool used in this study. A total of 49 samples of water, sediment and plants were prepared, with sampling carried out in the period from October 2015 to May 2017. Two periods: autumn and spring were chosen for the study. During the autumn cycle, smaller variations in the values of δ13C in DIC were found compared to the spring cycle. The enrichment of dissolved inorganic carbon (DIC) in the heavy isotope during the spring period was caused by the dynamic growth of microorganisms. The process of assimilative reduction of dissolved inorganic carbon by aquatic organisms, which use inorganic carbon in biochemical reactions, occurred in the reservoir. This process led to an enrichment of DIC in the 13C isotope. The analysis of the sedimentary organic carbon revealed a greater enrichment in the heavy isotope of carbon (by about 3‰) in April compared to May. This is due to the growth of microorganisms responsible for degradation of sedimentary organic matter and plant detritus. The sediment and the water column were shown to interact through the exchange of carbon.
The Leader Programme as an Impulse for New Projects in Rural Areas
Authors: Hoffmann Robert , Hoffmann Natalia
Published: April 2018

The article aims to present the stages of the LEADER programme and its influence on greater activity and integration of inhabitants by, e.g. extending the knowledge of tradition and national heritage and the actions intended for the integration of local communities. It is noticeable particularly in the implementation of the activities within Axis 4 of the 2007–2013 Rural Development Programme. Positive changes in rural areas are a result of building strong social and human capitals, which are important factors of local development. The skills and the ability for cooperation of a local community allows it to implement many projects. The investments made by beneficiaries of the LEADER programme improve the level of living and the quality of life in the countryside. The effect is an improvement in physical infrastructure and tourist attractiveness as a result of care for the rural landscape and cultural heritage. The implementation of the LEADER programme is presented on the example of Wielkopolskie Voivodeship where the participation in actions for local communities is deeply ingrained. In order to show spatial differences in the activity of local entities under Local Action Groups in Wielkopolskie Voivodeship, classes were selected on the basis of funds received by local entities in the LAG areas. There are 36 Local Action Groups operating in Wielkopolska (of which 31 have seats in this region).
Regional Development in Central-Eastern European Countries at the Beginning of the 21st Century: Path Dependence and Effects of EU Cohesion Policy
Authors: Dyba Wojciech , Loewen Bradley , Looga Jaan , Zdražil Pavel
Published: April 2018

Cohesion Policy has provided new impulses for development in Central and Eastern European Countries (CEECs) that continue to be challenged by regional disparities. This paper investigates the effects of the European Union Cohesion Policy on regional development. After presenting historical development patterns of the investigated area and opportunities afforded by this policy, its effects on a variety of indicators are analysed for the period 2007–2014. The analysis allowed confirming positive effects of EU Cohesion Policy on the development of CEE regions. However, these effects differ across the investigated area. Moving forward, it will be crucial to develop institutions and policies characteristic to each region that are stable and efficient without external funds.
Pelvic reconstruction with bone cement and total hip prosthesis after resection of chondrosarcoma. Case Report
Authors: Japie Ioan Mihai , Bădilă Adrian , Rădulescu Radu , Mitroi Eduard , Bujdei Andra , Dumitru Adrian , Ene Răzvan , Papuc Alexandru , Cîrstoiu Cătălin
Published: April 2018

Introduction. Chondrosarcoma is a malignant tumor of cartilaginous origin representing approximately 20-30% of all bone malignant tumors and occupying the second place in terms of their incidence. It usually affects adults between 40 and 60 years old, but can be encountered at older ages as well.

Materials and methods. We report the case of a 55-year-old male patient who presented to our department with 2 weeks-long right hip pain and partial loss of functionality in right limb. We performed X-rays, magnetic resonance imaging, computed tomography, bone scintigraphy, and angiography, which established the diagnosis of pelvic tumor. Biopsy of the tumor was performed by iliofemoral approach and its result showed moderately differentiated chondrosarcoma. Orthopaedic surgery was performed, with tumoral removal within oncological limits, pelvic reconstruction using acrylic bone cement impregnated with Vancomycin and total hip arthroplasty.

Results were assessed using the Musculoskeletal Tumor Rating Scale and a score of 23 out of 35 was obtained (the higher the better). Postoperative complications consisted in flap-skin necrosis that resolved within 2 months after surgery.

Conclusion. Bone defects repair using antibiotic impregnated cement drastically reduced the rate of postoperative infections, thus decreasing both morbidity and mortality. In spite of technological advancement, long-term prognosis remains reserved in chondrosarcoma, due to its specific aggressivity, resistance to chemo- and radiotherapy and high rate of recurrence.
The impact of extreme genu varum and genu valgum on postoperative outcomes using mini-subvastus approach in TKA
Authors: Creţu Bogdan Ştefan , Dragosloveanu Călin , Cotor Dragoş , Dragosloveanu Şerban , Stoica Cristian Ioan
Published: April 2018

Increasing interest in using minimally invasive approaches in TKA has led to the question: how much deformity is accepted for using MIS in TKA? A single surgeon performed 87 consecutive TKAs with mini-subvastus approach, using unconstrained prosthesis in 84 knees and constrained prosthesis in 3 knees. We conducted a prospective study in which patients were divided into two groups according to preoperative tibiofemoral axes (TFM), one group with 160°<TFM<195° and the second group with 160°≥TFM≥195°. Clinical and radiographic outcomes were compared. Postoperative ROM and knee score were improved in both groups, with similar results (p<0.01). Postoperative radiographic analyses showed that TFM was improved in both groups (p<0.01) with the coronal alignment inferior in 160°≥TFM≥195° group than the 160°<TFM<195° group. The results of this study suggest that mini-subvastus approach is a proper technique to use in primary TKA in patients with a TFM angle less than 160° and more than 195° with similar results with TFM angle between 160° and 195°, and for the use of constrained prosthesis designs with promising results. Preoperative TFM angle less than 160° and greater than 195° increases the risk of component malposition in coronal plane.
An update on osteoporosis
Authors: Bodean Oana , Munteanu Octavian , Voicu Diana , Arsene Luciana , Uzunov Ana , Pauleţ Florina , Cîrstoiu Monica
Published: April 2018

With the growth of the aging population worldwide, osteoporosis represents a serious health problem, which implies higher morbidity and costs, despite the continuous advances in treatment options. It involves both sexes, although menopausal women are mainly affected. This article is a brief review of literature on current osteoporosis treatment options.
INFLUENCE OF WATER SOLUBLE FERTILIZERS ON GROWTH IN BRINJAL HYBRID (Solanum melongena L.)
Authors: ANBURANI A.
Published: April 2018

In the present study, a field investigation was carried out to study the effect of water soluble fertilizers on growth and yield parameters of brinjal hybrids due to application of various levels of water soluble fertilizer. Foliar spray of NPK with 5 and 7 sprays, each starting from 30 DAT at 10 days interval, formed twenty treatments in two hybrids. The results showed that among the two different concentrations of foliar applied nutrients, 7 sprays of 1% NPK (19:19:19) along with 100 per cent recommended dose of fertilizer (200:150:100 kg ha-1) recorded the highest plant height, number of primary branches, secondary branches, stem girth, number of leaves per plant, leaf area.
INFLUENCE OF CADMIUM ON GROWTH AND BIOCHEMICAL CONTENTS OF TOMATO PLANTS
Authors: P. Vijayarengan A. Natarajan, , Vijayaragavan M.
Published: April 2018

The increasing concentrations (10, 25, 50, 75 and 100 mg /kg) of soil cadmium on growth and biochemical contents in tomato plants were analysed on 30th sampling days. Control plants were maintained separately. Plants were grown in pots containing 3 kg of air dried sandy loam soil and treated with different concentrations (mg/kg) of cadmium (0, 10, 25, 50, 75 and 100 ). Treatments decreased the growth parameters such as root and shoot length  and biochemical constituents such as, protein,(except, proline and  phenol content) contents in tomato plants compared to untreated plants. The shoot length of cadmium treated tomato plants was higher than the root length. proline and phenol content of root of  tomato plants was higher than the shoot.
O POSITIVISMO JURÍDICO E A INFUNDAMENTABILIDADE DOS DIREITOS HUMANOS: UMA CRÍTICA A PARTIR DA ÉTICA DA LEI NATURAL
Authors: Souza Elden Borges , Pinheiro Victor Sales
Published: April 2018

O discurso contemporâneo acerca dos direitos humanos concentrou todos os seus esforços no reconhecimento e na efetivação desses direitos. Uma das consequências de tal esforço político é a crescente positivação nacional e internacional. No entanto, o efeito desse gesto é a negação da necessidade de uma fundamentação filosófica dos direitos humanos. Portanto, o positivismo jurídico passa a ser o sustentáculo desses direitos. No entanto, principalmente a partir de Finnis, a lei natural recuperou espaço e passou a impugnar essa possibilidade. Portanto, o problema analisado no presente trabalho é a crítica da lei natural à fundamentação dos direitos humanos em uma visão positivista do Direito. A partir de uma revisão bibliográfica, o presente trabalho identificou a insuficiência do positivismo jurídico na fundamentação dos direitos humanos, principalmente ao considerar as principais críticas formuladas pelo direito natural.
OS DIREITOS HUMANOS NA FORMAÇÃO INTELECTUAL DO JOVEM MARX
Authors: Castro Matheus Felipe de
Published: April 2018

O presente artigo aborda o humanismo na formação do pensamento intelectual do jovem Marx. Busca entender como esse humanismo influenciou a sua obra de maturidade. Como se sabe, Marx foi um crítico dos Direitos Fundamentais, que para ele eram direitos da sociedade burguesa. Isso leva ao seguinte problema: apesar dessa crítica, Marx seria ou não seria essencialmente um pensador humanista? Para realizar a tarefa proposta, adotamos como método a análise dos textos escritos entre 1843-1844, destacando nesses textos elementos que possam subsidiar o entendimento do problema aqui proposto. O referencial teórico, naturalmente, se circunscreve ao próprio marxismo.
DIREITO DA ANTIDISCRIMINAÇÃO E DIREITOS DE MINORIAIS: PERSPECTIVAS E MODELOS DE PROTEÇÃO INDIVIDUAL E COLETIVO
Authors: Rios Roger Raupp , Cogo Leivas Paulo Gilberto , Schäfer Gilberto
Published: April 2018

O artigo objetiva analisar o desenvolvimento do direito da antidiscriminação e do direito das minorias, considerados na perspectiva dos direitos humanos e em sua inserção neste campo do conhecimento. Cuida-se de pesquisa teórica, mediante o exame da bibliografia pertinente e visando à exploração das compreensões vigentes destas categorias, proporcionando maior familiaridade com o problema. Nessa tarefa, salienta a origem comum, tensões e limites destes dois campos do conhecimento e da técnica jurídica, enquanto concretizações do direito humano e fundamental de igualdade. Procede a uma análise comparativa entre algumas técnicas e as perspectivas empregadas por tais campos jurídicos, concluindo pela necessidade de uma compreensão adequada do conceito de direito coletivo como categoria central para a efetividade do direito antidiscriminatório, enfatizando os modelos individual e grupal de proteção jurídica do direito de igualdade.
LA EMERGENCIA DE LA ÉLITE EVANGÉLICA EN EL ACTUAL PROCESO DEMOCRÁTICO DE BRASIL
Authors: Gerardi Dirceu André , Espinoza Fran
Published: April 2018

En la actual democracia brasileña, así como en otras sociedades modernas, las fronteras entre la religión y la política no son claras o fijas, ellas extrapolan los campos (Dantas, 2011). El objetivo del presente trabajo es analizar la emergencia de élite evangélica en Brasil, para eso se identificará el perfil de los candidatos y electos a diputados que en el momento de la inscripción informaron al Tribunal Superior Electoral (TSE) nombres asociados a la posición ejercida en iglesias evangélicas, como los pastores(as) y bispos(as), presbíteros, reverendos, apóstoles(as), misioneros y hermanos(as). El estudio analizará las principales características sociales de los candidatos y los elegidos para diputado federal entre las elecciones de 1998 y 2014. Se busca identificar por cuales partidos se candidatean y qué tipo de perfil poseen. El estudio pretende comprobar las siguientes hipótesis: i) los evangélicos que lanzaron candidaturas para concurrir a cargos de diputado federal presentan perfil educacional bajo y se concentran en partidos políticos de derecha; y ii) los evangélicos que poseen carrera electiva anterior a la candidatura presentan mayores oportunidades de ser elegidos. La mayoría de las candidaturas de evangélicos ocurre en los partidos de derecha y tienen la educación media. Los pastores y bispos con carrera electiva anterior tienen más probabilidades de ser elegidos.
A REFORMA POLÍTICA BRASILEIRA À LUZ DOS INSTITUTOS PLEBISCITO E REFERENDO: MAIS UMA PROPOSTA À DEMOCRACIA
Authors: Ferrer Walkiria Martinez Heinrich , CARDOSO GLEISSA MENDONÇA FARIA , CARDOSO GLEISSA MENDONÇA FARIA
Published: April 2018

A Constituição Brasileira prevê que o poder emana do povo, no entanto, não tem tradição de utilizar os instrumentos de participação direta popular, notadamente, Plebiscito e Referendo. Nesse sentido, essa pesquisa desperta um olhar para a importância da utilização desses institutos nas deliberações do governo, como forma de inserir e incentivar o povo a participar de decisões fundamentais para o desenvolvimento do país, em especial, a Reforma Política. Este estudo tematizou a reforma política brasileira à luz dos institutos da democracia semidireta plebiscito e referendo. Tem-se como objetivo geral demonstrar qual instituto da democracia semidireta plebiscito ou referendo seria o mais adequado a ser utilizado em uma reforma política no Brasil. Especificamente buscou pesquisar o contexto político e social para o exercício da democracia no Brasil, conceituar plebiscito e referendo e sua aplicabilidade nas Constituições brasileiras, e por fim, analisar qual mecanismo de participação popular, plebiscito ou referendo, melhor oportuniza o exercício da soberania popular e os posicionamentos sobre a proposta de utiliza-los em uma reforma política no Brasil. O método de estudo figura-se dedutivo, partindo-se de teorias e leis gerais para a análise e explicação de fenômenos particulares. Conclui-se que, o plebiscito é concebido como a aquisição de maior relevância para a efetivação da soberania popular, e que a participação popular, tão importante na conquista da democracia, denota-se essencial para as decisões relevantes voltadas a definir a reforma política no Brasil.Democracia. Plebiscito. Referendo. Reforma Política
O ESTUPRO DE VULNERÁVEL NA PERSPECTIVA DA PROTEÇÃO INTEGRAL DE DIREITOS A CRIANÇAS E ADOLESCENTES – A UNIFORMIZAÇÃO DA INTERPRETAÇÃO DO SUPERIOR TRIBUNAL DE JUSTIÇA
Authors: Dias Felipe Da Veiga
Published: April 2018

O estudo ora proposto tem com tema o estupro de vulnerável, a partir de uma análise com base na Teoria da Proteção Integral, enfatizando-se a questão jurisprudencial do Superior Tribunal de Justiça e sua uniformização recente. Nesse sentido, o problema de pesquisa delimitado foi a determinação, se nos casos de estupro de vulnerável ocorreu ou não, o respeito a atual matriz teórica da infância no processo de uniformização do Superior Tribunal de Justiça? O objetivo central da pesquisa é proporcionar uma apreciação crítica não apenas da uniformização, mas igualmente dos posicionamentos principais que foram adotados até esse procedimento por parte da Corte superior (e por vezes nas demais instâncias). Assim o estudo segue da abordagem da infância até a atuação do direito penal, no combate a violência e violação de direitos, para ao final adentrar na apreciação jurisprudencial. Adota-se no estudo o método dedutivo de abordagem, com destaque para técnica de pesquisa da documentação indireta de fonte primária, jurisprudência, e bibliográfica. Conclui-se que a uniformização jurisprudencial do Superior Tribunal de Justiça, não somente encontra-se alinhada com a Teoria da Proteção Integral, como com as bases do Direito Constitucional e Penal, articulando uma decisão hermeneuticamente adequada, ao compreender a complexidade que interliga o Direito. Igualmente afastam-se os posicionamentos discricionários e opressivos aos direitos da infância, buscando assim concretizar a intervenção penal conectada a visão do Estado de Direito contemporâneo.
Revascularization of Chronic Occlusive Disease of a Right Pulmonary Artery Graft
Authors: Salamo Russell , Piening Nicholas , Joseph Garrity MD , Ismael Moreno MD , Kirubahara Vaheesan MD
Published: April 2018

Anomalous aortic origin of the left coronary artery (AAOLCA) is a rare occurrence. This anomaly may lead to myocardial ischemia and, therefore, surgical repair is recommended to improve long-term survival in these patients. We present a case of successful mobilization of an anomalous left main coronary artery, pulmonary artery translocation, and interposition graft to the right pulmonary artery with a late complication of the right pulmonary artery graft occlusion. This case illustrates the difficulty in the recanalization of pulmonary artery graft occlusion and stenosis, and highlights the utility of treatment via a staged approach.
Synthesis of RNA nucleotides in plausible prebiotic conditions from ab initio computer simulations
Authors: Pérez-Villa Andrea , Saitta A. Marco , Georgelin Thomas , Lambert Jean-François , Guyot François , Maurel Marie-Christine , Pietrucci Fabio
Published: April 2018

Understanding the mechanism of spontaneous formation of ribonucleotides under realistic prebiotic conditions is a key open issue of origins-of-life research. In cells, de novo and salvage nucleotide enzymatic synthesis combines 5-phospho-α-D-ribose-1-diphosphate (α-PRPP) and nucleobases. Interestingly, these reactants are also known as prebiotically plausible compounds. Combining ab initio molecular dynamics simulations with recently developed reaction exploration and enhanced sampling methods, we show that nucleobases and α-PRPP should spontaneously combine, under mild hydrothermal conditions, with an exothermic reaction and a facile mechanism, forming both purine and pyrimidine ribonucleotides.

Surprisingly, this mechanism is very similar to the biological one, and yields ribonucleotides with the same anomeric carbon chirality as in biological systems.

These results suggest that natural selection might have optimized -- through enzymes -- a pre-existing ribonucleotide formation mechanism, carrying it forward to modern life forms.
Large–Scale Computational Screening of Molecular Organic Semiconductors Using Crystal Structure Prediction
Authors: Yang Jack , De Sandip , Campbell Joshua E , Li Sean , Ceriotti Michele , Day Graeme
Published: April 2018

Predictive computational methods have the potential to significantly accelerate the discovery of new materials with targeted properties by guiding the choice of candidate materials for synthesis. Recently, a planar pyrrole azaphenacene molecule (pyrido[2,3-b]pyrido[3`,2`:4,5]-pyrrolo[3,2-g]indole, 1) was synthesized and shown to have promising properties for charge transport, which relate to stacking of molecules in its crystal structure. Building on our methods for evaluating small molecule organic semiconductors using crystal structure prediction, we have screened a set of 27 structural isomers of 1 to assess charge mobility in their predicted crystal structures. Machine--learning techniques are used to identify structural classes across the landscapes of all molecules and we find that, despite differences in the arrangement of hydrogen bond functionality, the predicted crystal structures of the molecules studied here can be classified into a small number of packing types. We analyze the predicted property landscapes of the series of molecules and discuss several metrics that can be used to rank the molecules as promising semiconductors. The results suggest several isomers with superior predicted electron mobilities to 1 and suggest two molecules in particular that represent attractive synthetic targets.
Crisis y austeridad: amenaza para el empleo femenino en las regiones europeas
Authors: Martínez-Tola Elena , De la Cal-Barredo Ma. Luz , Alvarez-González Irantzu
Published: April 2018

El objetivo del trabajo es explorar la relación entre las tasas de paro de mujeres y de hombres, y la variación en el empleo público a escala regional. Para ello se plantean diversos indicadores orientados al análisis descriptivo del desempleo a nivel regional en el ámbito de la UE-15 y se hace una mapificación de los resultados. La principal conclusión es que la importante segregación sectorial del empleo por sexo y el papel que desempeña el empleo en el sector público en el trabajo femenino deben ser tomados en cuenta a la hora de diseñar las políticas laborales. De lo contrario, el fomento del empleo en ciertos sectores y/o los recortes de gasto público en otros incorporan un sesgo que puede estar impulsando el empleo masculino y retrasando la recuperación del femenino.
Interculturalidad en Educación Superior: Experiencia en Educación Inicial en La Araucanía, Chile
Authors: Morales-Saavedra Soledad , Quintriqueo-Millán Segundo , Uribe-Sepúlveda Pilar Andrea , Arias-Ortega Katerin
Published: April 2018

: El objetivo del artículo es presentar resultados de la experiencia desarrollada en los procesos de formación inicial docente. La metodología consistió en la sistematización de dichas experiencias. Por lo tanto, pretende ser un aporte para fortalecer los procesos de enseñanza de educadores de párvulos. El problema que se aborda se relaciona con que, históricamente, la escolarización de niños/as indígenas se realiza sobre la base de contenidos y finalidades educativas monoculturales occidentales. La investigación sostiene como supuesto que en las familias y comunidades indígenas mapuches presentes en Chile existen conocimientos asociados a prácticas socioculturales, que permitirían sustentar una Educación Parvularia, desde un enfoque educativo intercultural, con base epistémica en la memoria social de padres y sabios. Los principales resultados develan temas claves en la formación, respecto a los saberes para una educación intercultural para niños menores de seis años, fortaleciendo la comunicación y trabajo con la familia y la comunidad.
La nueva configuración del sistema de partidos valenciano. Una aproximación institucionalista
Authors: López María Angeles Abellán , Beneyto Gonzalo Pardo
Published: April 2018

El objetivo del artículo es explicar la evolución del sistema de partidos de la Comunitat Valenciana (España) entre 1978 y 2015. Se parte de un enfoque neoinstitucionalista y de una metodología centrada en el análisis histórico (path dependence y critical junctures) de los cambios producidos en los partidos políticos, en cuanto a la cartelización y la identidad valenciana, y su caracterización actual. Así, se han generado tres subhipótesis de trabajo: H1a: los partidos han tenido una dinámica continuista que ha variado por cambios bruscos del entorno; H1b: las fuerzas políticas han aprovechado dichos acontecimientos para obtener rédito electoral; y H1c: los actuales partidos políticos son fruto de los cambios experimentados en el periodo estudiado. Esta hipótesis compleja abre nuevos campos de estudio para futuras investigaciones en cuanto a estrategia, discurso y percepciones sobre estas organizaciones.
Desaparición forzada y trauma cultural en México: el movimiento de Ayotzinapa
Authors: Gravante Tommaso
Published: April 2018

La desaparición de los 43 estudiantes de Ayotzinapa en 2014 dio vida a una amplia e inusual respuesta por parte de la sociedad civil mexicana. La pregunta a que responde la investigación es: ¿qué sucedió en esta ocasión para que se generara una amplia movilización ciudadana? Apoyándome en la propuesta de Jeffrey Alexander de trauma cultural, raramente utilizada en el análisis de la acción colectiva, analizaré el porqué y de qué forma la sociedad mexicana ha enmarcado los hechos de Ayotzinapa. El análisis se fundamenta en el trabajo etnográfico realizado a lo largo de un año (septiembre 2014-2015) durante las distintas manifestaciones en solidaridad con los padres de los estudiantes desaparecidos realizadas en la Ciudad de México y de 70 entrevistas realizadas en la manifestación nacional del 26 de septiembre de 2015, que conmemoraba un año de la desaparición de los 43 estudiantes normalistas.
Case Based Reasoning Untuk Diagnosis Penyakit Demam Berdarah
Authors: Adawiyah Rabiah
Published: April 2018

Dengue virus is a virus that causes dengue fever (DD), dengue hemorrhagic fever (DBD) and dengue shock syndrome (SSD). This disease is included in the status of outbreaks at the Hospital Benjamin Guluh Kab. Kolaka. The inclusion of this disease in the status of outbreaks then there are many cases / patients are handled every year even every month. The symptoms of a patient diagnosed with dengue fever tend to be similar. Case Based Reasoning (CBR) is one of the methods that can make or solve problems based on the existing case as a solution of new problem. The system built in this study is the CBR system to make a diagnosis of Dengue Fever. The diagnostic process of incorporating new problems compared to old cases then calculated the value of similarity. In this research, Nearest neighbor method is used for similarity process. Tests used 54 cases as randomized test data and 85 cases were used as case basis. The results obtained are 98.14% sensitivity and 99.25% accuracy.
Implementasi Metode Reynolds menggunakan Simulasi Kerumunan Bebek
Authors: Andriyanto Sidhiq , Suyanto M. , Sukoco Sukoco
Published: April 2018

"Simulation of Duck Crows Using Reynolds Method" is a study with the aim to find out the behavior of duck breeding crowd. The next goal is to make a crowd simulation using the Reynolds method. Limitations of this research variable is the object of research on adult duck Turi, the method used is Reynolds method. The simulations are made using Unity3D software in the form of 3D and the animation provided is just a running gesture. The method of analysis of this research is using research and development method. The result of the research is the data of duck walking in the crowd to be applied in 3D animation. The end result of the study is a simulation of duck crowds that run on flat fields. Destination directions are affected by mouse input and can avoid obstacles when walking. This simulation uses Reynolds basic rules of cohesion, alignment and separation.The conclusion of the research is that there is a similarity between the simulation of the crowd with the movement of the original duck crowd and the Reynolds method can be applied in the simulation of the duck crowd in 3D. Research produces 3D animation of duck crowds that are given the ability to avoid obstacles and target goals determined by mouse input.
Metropoliten Yönetimlerde Hizmet Sorumluluklarının Paylaşımı ve Finansmanı
Authors: Arıkboğa Ülkü
Published: April 2018

Günümüzde büyük ölçekli ve yoğun nüfuslu
metropoliten kentlerin yönetiminden sorumlu olan yönetim birimleri, planlama,
su ve kanalizasyon, ulaşım, altyapı, hava kirliliği ile mücadele, konut gibi
bir dizi sorunla karşı karşıyadır. Belirtilen sorunların çözümü ve metropoliten
alanlarda artan ve çeşitlenen hizmet talebinin etkin bir şekilde
karşılanabilmesi noktasında metropoliten alanların nasıl yönetileceği konusu
önemli bir sorun olarak ortaya çıkmaktadır. Diğer yandan farklı yönetim
otoriteleri arasında hizmet sorumluluklarının nasıl paylaşılacağı ve
hizmetlerin hangi kaynaklarla finanse edileceği bu konuda çözüme kavuşturulması
gereken diğer sorunlardır.  Makalede,
metropoliten yönetimlerde hizmet sorumluluklarının çeşitli yönetim kademeleri
arasında paylaşımı ve finansmanı konusu analiz edilmeye çalışılmıştır. Makale
kapsamında, öncelikle literatürde metropoliten alanların yönetimi konusunda
çeşitli uygulamalardan yola çıkılarak geliştirilen yönetim modellerinden
bahsedilmiştir. Daha sonra metropoliten alanlarda hizmet sorumluluklarının
çeşitli yönetim kademeleri arasında nasıl paylaştırıldığına bakılmıştır. Son
olarak metropoliten yönetimlere sağlanan finansman kaynakları incelenmiştir.
Metropoliten yönetimlerdeki hizmet paylaşımı ve finansman konusu,  hem teorik olarak, hem de farklı ülkelerdeki
çeşitli metropol örneklerinden yola çıkılarak incelenmiştir.  
Studi Tokoh Debora dalam Kitab Hakim-Hakim 4-5: Menjawab Isu Kontemporer Kepemimpinan Wanita Dalam Organisasi Kristen
Authors: Wijaya Elkana Chrisna
Published: April 2018

Abstract. The most dominant issue in contemporary leadership is gender issues. The position of men is considered more special than women. This view has led to the emergence of discriminatory practices against women, not least in the world of Christianity. The views of conservative theologians in relation to the realm of leadership are not so different from the above. The stereotype is often a strong reason for restricting or forbidding women to become leaders. Through this study, the author analyzes some important sections of the text from Judge 4-5 through the character analysis method, to answer the polemic and to the understanding that the effectiveness of a leader is not based on gender. Through this analysis the result is that there is no partiality to one gender in the election of a leader in the midst of God's people.Abstrak. Isu yang paling dominan dalam kepemimpinan kontemporer adalah isu gender. Kedudukan laki-laki dipandang lebih istimewa dibandingkan perempuan. Pandangan tersebut menyebabkan munculnya praktik diskriminasi terhadap kaum perempuan, tidak terkecuali dalam dunia Kekristenan. Pandangan para teolog konservatif sehubungan dengan ranah kepemimpinan, tidak berbeda jauh dengan pandangan tersebut di atas. Stereotype tersebut seringkali menjadi alasan yang kuat untuk membatasi atau melarang wanita untuk menjadi pemimpin. Melalui penelitian ini, penulis menganalisis beberapa bagian teks yang penting dari Kitab Hakim-hakim 4-5 melalui metode analisis tokoh, untuk menjawab polemik tersebut dan pemahaman bahwa keefektifan seorang pemimpin, tidak berdasarkan pada gender. Melalui analisis tersebut diperoleh hasil bahwa tidak ada keberpihakan terhadap satu gender dalam terpilihnya seorang pemimpin di tengah-tengah umat Allah.
Analisis Historis terhadap Teologi Gerakan Pentakostalisme
Authors: Sutoyo Daniel
Published: April 2018

Abstract. The purpose of this paper is to explain the historical developments, doctrines and behaviors that appear in every Pentecostal movement, so that we can distinguish between the First Wave movement, the Classical Pentecost, the Second Wave Movement, the Charismatic Movement, the Third Wave Movement, the Sign Movement and the Miracles, and Fourth Wave Movement, New Apostolic Reformation Movement (NAR). The method in this study is the study of historical analysis on the history of the development of each wave movement Pentecostalism. Through the analysis it is concluded that every wave of the Pentecostal movement is a movement that comes from God, through the work of His Holy Spirit. Although in practice there is a distorted phenomenon, but can not be generalized and then assume everything is heretical.Abstrak. Tujuan penulisan ini adalah menjelaskan sejarah perkembangan, doktrin dan perilaku yang muncul setiap gerakan Pentakostalisme, sehingga kita dapat membedakan antara gerakan Gelombang Pertama, Pentakosta Klasik, Gerkan Gelombang Kedua, Gerakan Kharismatik, Gerakan Gelombang Ketiga, Gerakan Tanda-tanda dan Mujizat-mujizat, dan Gerakan Gelombang Keempat, Gerakan New Apostolic Reformation (NAR). Metode dalam penelitian ini adalah penelitian analisis historis terhadap sejarah perkembangan setiap gerakan gelombang Pentakostalisme. Melalui analisis tersebut disimpulkan bahwa setiap gelombang gerakan Pentakostalisme adalah sebuah gerakan yang berasal dari Tuhan, melalui karya Roh Kudus-Nya. Meskipun dalam praktiknya ditemukan fenomena yang menyimpang, namun tidak dapat digeneralisasikan dan kemudian menganggap semuanya sesat.
Bir Anadolu Kentinin Kuruluş ve Gelişmesinde Sanayinin Etkisi: Ayancık Örneği
Authors: Kaya Mutlu , Yılmaz Cevdet
Published: April 2018

Ayancık, Karadeniz
Bölgesi kıyı kuşağında Sinop ilinin gelişmiş ilçelerinden biridir. İlçe merkezi
olan bugünkü Ayancık kenti, Cumhuriyetin ilk yıllarında kaza merkezi olmakla
birlikte, küçük bir köy görünümündedir. 1929 yılında yöredeki zengin bitki
örtüsüne bağı olarak ilçe toprakları üzerinde kurulan orman işletme sistemi ve
bunun merkezi kısmını oluşturan Ayancık’ta inşa edilen kereste fabrikası bu
küçük yerleşmenin kaderini değiştirmiş, Ayancık Cumhuriyet Türkiye’sinin
fonksiyonel anlamda ilk sanayi kentlerinden biri olmuştur.Ayancık ilçe merkezinde
yabancı sermayeli bir şirket olarak kurulan ZİNGAL T.A.Ş. kısa zamanda yöre üzerinde
etkisini göstermiş, orman işletme sahasında çalışan 3000 işçiden ayrı olarak, fabrikada
çalışan 600 işçisi ile o günkü nüfusuna oranla, yaşayanların neredeyse
yarısından fazlası geçimini endüstriyel faaliyetten sağlamaya başlamıştır.
1930’ların başlarından itibaren artık fonksiyonel anlamda bir sanayi kenti olan
Ayancık’ın ekonomik, sosyal ve kültürel yapısı hızla değişmiştir. Sineması,
hastanesi, halkevi, veterineri, tenis kortu vb. modern spor alanlarına kavuşan
Ayancık, bu fabrika ve işletme sayesinde Türkiye’de elektriğe en erken kavuşan
yerleşmelerden de biri olmuştur.

Araştırmada kentsel
yerleşmenin oluşumu ve gelişiminde ana etken olan yöredeki geniş ve verimli
ormanlara bağlı olarak kurulan kereste fabrikasının
etkisiyle bir sanayi kasabasının ortaya çıkışı ve getirdiği yenilikler ile onu
Cumhuriyetin ilk yıllarında diğer kentlerden farklı kılan sebepler Ayancık
örneğinde açıklanmaya çalışılmıştır. Bu araştırmada çalışma alanı Ayancık ilçe merkezi ile sınırlandırılmış,
kırsal alan dahil edilmemiştir.
Değer Eğitiminde Kısa Filmlerden Yararlanma: Örnek Bir Uygulama
Authors: Aladağ Elif , Karaman Burcu
Published: April 2018

Kısa
filmler, uzunluğu ülkelere göre farklılık gösteren ama genellikle 35 mm filmlerde
bir ile üç makara arasında değişen filmlerdir. Kısa filmleri uzun metrajlı
filmlerden ayrılan özelliği süresi ve öykü yapısıdır. Kısa filmlerin süresiyle
ilgili net bir tanım olmasa da genel olarak 5-17 dakika arasında sürebilir.
Öykü yapısındaki fark ise anlatımı yalın, sade ve kısa süre içinde anlam
yoğunluğunu verebilmesidir. Bu çalışmanın amacı ilgili alan yazın
taranarak kısa filmlerin ne olduğu ve eğitimde nasıl kullanılması gerektiğine
yer verilmesidir. Ayrıca eğitimde kısa film kullanımının değer eğitimi
açısından önemi irdelenmeye çalışılmıştır. Çalışma sonunda kısa filmlerin değer
öğretiminde kullanımı ile ilgili örnek bir uygulama sunulmuştur. Örnek
uygulamadaki kısa filmler EBA’ da yer alan ödüllü kısa filmler içinden çocuğa
görelik ilkesi ve kısa filmlerde bulunması gereken özellikler göz önünde
bulundurularak seçilmiştir.
ANALISIS FAKTOR-FAKTOR YANG MENDORONG KINERJA DOSEN TETAP PADA FAKULTAS KOMUNIKASI DAN BISNIS UNIVERSITAS TELKOM
Authors: Andini Andini , Arwiyah Yahya , Pangarso Astadi
Published: April 2018

Related to the performance of the homebase lecturers  at the Faculty of Communications and Business, Telkom University, in conduct the Tri Dharma Perguruan Tinggi (Three Pillars of Tertiary Education), research and community service feels lacking. That is why this research is intended to know the performance condition also to see the factors that encourage and the factors that are dominant towards the performance of fixed lecturers at the Faculty of Communications and Business in Telkom University. The method that is used  in this research is descriptive analysis with factor analysis technique. The type of this research is quantitative research. The respondants in this research are the fixed lecturers at the Faculty of Communications and Business in Telkom University. The research data is obtained by distributing questionnaires towards 70 respondants and literature review. Based on the descriptive analysis result, fixed lecturers performance in the "good" category is about 77%. Factor analysis results states that ability factor, organizational structure factor, background factor, and perception factor are the factors that encourage the performance of the fixed lecturers at the Faculty of Communications and Business in Telkom University. The ability factor which is representated by attitude, motivation, expertise, discipline, effectivity, and efficiency factors has the highest value % of variance that is about 34,837%. Organizational structure factor which is representated by resource, leadership, work experience, and work design factor has the value % of variance about 10,588%. Background factor which is representated by initiative and demography factor has the value % of variance about 8,533% while the perception factor has the value % of variance about 7,630%.

Keyword:Performance, Factor Analysis, Faculty of Communications and Business in Telkom University, lecturer performance