bluuebunny/crossref_metadata_2025 huggingface dataset:
The Effect of Applying the Iodized Contrast Materials Used in Hysterosalpingography at Body Temperature or Room Temperature on Visual Analogue Scale Scores
Authors: ERSAK Burak , TAŞÇI Yasemin , BEDİR FINDIK Rahime , TUĞRUL ERSAK Duygu , TOKMAK Aytekin , KOKANALI Mahmut Kuntay
Published: October 2022

Aim: To compare pain scores of infertile patients during and after hysterosalpingography (HSG) procedure using visual analoge scale (VAS) between cold and warm contrast medium and to investigate whether using warm contrast can alter spontaneous pregnancy rate.

Materials and Methods: Prospective randomized study between March-September 2017. Primary infertile patients undergoing HSG procedure. Patients’ age, body mass index (BMI), history of previous surgery, duration of infertility and pain levels during the most painful menstrual period were recorded. The pain severity was questioned during and at the 30th minute after the procedure using VAS. While patients who underwent HSG using a contrast medium at body temperature 37 °C were defined as warm group(n:55), patients who underwent HSG using a contrast medium at room temperature 23 °C were defined as cold group (n:55).

Results: There were no significant differences between the groups in terms of age, BMI, duration of infertility, previous surgery and VAS during menstruation. The mean duration of HSG of warm group patients was significantly lower(p=0.001). Warm group patients’ mean VAS score during and 30 minutes after HSG were significantly lower than in the control group ( 5.3±4.2 vs 7.5±2.0), (1.1±0.9 vs 2.4±1.4), respectively. While severe pain percentage during HSG in warm group was 25.5%, it was 66.7% in the control group. In logistic regression analysis, warm and cold groups were only found as significant related factors for severe pain felt during procedure (p
Peningkatan Kesadaran Lingkungan Melalui Bank Sampah dan Teknologi IPAL Rumah Tangga
Authors: Abdullah M. Hasan
Published: October 2022

Lingkungan yang sehat merupakan kebutuhan masyarakat. Namun kesadaran masyarakat terhadap kebutuhan tersebut tidak sesuai dengan kenyataan.  Sampah dan Sanitasi air limbah rumah tangga merupakan masalah yang belum terselesaikan. Warga masih membuang sampah pada lahan kosong atau di pinggir jalan. Warga juga masih melakukan bung air besar (BAB) di sungai. Program pengabdian masyarakat melalui Kuliah Kerja Mahasiswa (KKM) ini dilaksanakan di RW 04, Kecamatan Tambak Osowilangon. Kegiatan ini dilakukan dengan memberikan pelatihan pengelolaan sampah rumah tangga melalui bank sampah dan pembuatan teknologi IPAL (Instalasi Pengolahan Air Limbah) yang sehat dan murah. Hasil dari program pengabdian ini adalah tumbuhnya kesadaran masyarakat untuk menjaga kesehatan diri dan lingkungan. Masyarakat dapat mengelola sampah secara mandiri melalui bank sampah dan memiliki IPAL yang ramah lingkungan.
PEMBERDAYAAN UMKM DAN EDUKASI PROTOKOL KESEHATAN DI WILAYAH RT 03 RW 01 GUNUNG ANYAR SURABAYA
Authors: Yuliastuti Retno Ayu , Wasil Mohammad , Alda Achmad Naufal , Sandra Alda Prahtitis Apitya , Coo Anita , Insulina Devi , Pratama Ksatria Bagus , Sari Lelyana Nur Indah , Indawati Siti Eka , Vitasari Zeni Nor
Published: October 2022

Pandemi covid 19 sangat berdampak pada masyarakat terutama padakesehatan dan ekonomi, Pada wilayah RT 03 RW 01 Gunung Anyar kami melakukansurvey dan observasi, beberapa masalah yang kami temukan seperti masyarakat yangtidak mematuhi pada protokol kesehatan sebagai kebijakan pemerintah untukmemutuskan rantai penyebaran covid 19, beberapa UMKM yang ada kami menemukanmasalah yaitu kurangnya kebersihan dan tidak mengenal dengan pemasaran online ataudigital marketing. Dengan hal tersebut kami melakukan pendekatan dengan metodeobservation, acceptable untuk mengumpulkan data data. Kami melakukan programkerja yaitu lingkungan sehat, penyuluhan covid 19 pada anak pendidikan usia dini danpenyuluhan UMKM. Dengan program tersebut hasil yang kami dapatkan masyarakatmulai mematuhi protokol kesehatan, dan UMKM mengenal digital marketing.
Surviving on Soy Salami: Dissidents, Exiles, Prisoners, and the Rhetoric of Affect in Postcommunist Romania
Authors: Ritivoi Andreea Deciu
Published: October 2022

After decades of being seen, or rather heard, through Radio Free Europe as moral and political authorities preserving Romania’s values and hopes from abroad, exiles of the Cold War had a disappointing political career in the postcommunist transitional society. The main figures hailing on behalf of historic pollical parties failed to win the election in 1990, and failed to convince the electorate that they could lead them to freedom and democracy. The former dissidents who had lived overseas likewise did not manage to become opinion leaders, at least not compared to local intellectuals, and eventually damaged each other’s reputation in public fights and scandals. Why weren’t these exiles, once so full of promise for a democratic future in Romania, more impactful? The answer may point to their systematic undermining orchestrated by the neo-communist power brokers of the transitional era. Yet the answer is rather more complicated, one that this paper offers by focusing on the rhetoric of the early postcommunist decade and its emphasis on the shared deprivation experienced under communism. The slogan built around hunger—“who ate soy meat with us”—was part of a larger effect of political survivalism that viewed exiles as outsiders. I show that the contest of moral superiority, pitting those who had been imprisoned against those who had fled, fed a rhetoric of suffering that would eventually marginalize the exiles and any political contribution they could have made after 1989.
The “Pure” Romanian: (Re)writing Romanian National Identity in Dan Puric’s
Romanian Soul
Authors: Nae Andrei
Published: October 2022

This paper investigates Romania’s auto-image as described by Dan Puric in his book
Suflet Românesc
(
Romanian Soul
). By employing imagology, this article first shows how Romanian national identity is constructed in opposition to Western culture and modernity. And by drawing on imagology and Hayden White’s approach to historiography, I provide a discursive analysis of the Romanian auto-image provided in the text. I show that Puric’s writing of Romanian national identity is a Romantic one rendered in the anarchist mode. The author alleges that Romanians are born with a “Romanian soul,” which guarantees their adherence to a Christian Orthodox worldview, one to which Western culture and modernity are inimical. The dominant metaphor used to represent Romanianness is the folktale, whose main traits—being set in
illo tempore
, a focus on a stark moral antithesis between good and evil where the former prevails, and favouring intuition over reason—are allegedly shared by “pure” Romanians. After revealing the pillars of Romanianness in Puric’s view, I trace the intellectual and cultural continuities between his Romanian auto-image and Romania’s far-right views on nation and nationhood, as well as the national communist view on Romanianness. As far as the former is concerned, I highlight the structural similarities between Puric’s nationalism and anti-Semitic discourse. With respect to the latter, I draw attention to Puric’s reliance on two of the several national communist myths identified by Romanian historian Lucian Boia: the myth of continuity and the myth of conspiracy. Puric’s book dovetails with national communist discourse by postulating the alleged continuity between the peoples and cultures that have existed in Romania’s current geographic location across the centuries and retains its communist fears of foreign conspiracy.
Gravitational Wave Acceleration to Relativistic Energies
Authors: Loeb Abraham
Published: October 2022

A charged particle can be accelerated to arbitrarily high energies by maintaining a permanent resonance with the phase of a planar gravitational wave propagating along a uniform magnetic field. The Doppler-shifted cyclotron autoresonance could potentially result in electromagnetic afterglows near gravitational-wave sources.
Transmission of a Seismic Wave Generated by Impacts on Granular Asteroids
Authors: Sánchez Paul , Scheeres Daniel J. , Quillen Alice C.
Published: October 2022

In this paper, we use a soft-sphere discrete element method code to simulate the transmission and study the attenuation of a seismic wave. Then, we apply our findings to the different space missions that have had to touch the surface of different small bodies in the solar system. Additionally, we do the same in regard to the seismic wave generated by the hypervelocity impacts produced by the DART and Hayabusa2 missions once the shock wave transforms into a seismic wave. We find that even at very low pressures, such as those present in the interior of asteroids, the seismic wave speed can still be on the order of hundreds of meters per second depending on the velocity of the impact that produces the wave. As expected from experimental measurements, our results show that wave velocity is directly dependent on P
1/6, where P is the total pressure (confining pressure plus wave-induced pressure). Regardless of the pressure of the system and the velocity of the impact (in the investigated range), energy dissipation is extremely high. These results provide us with a way to anticipate the extent to which a seismic wave could have been capable of moving some small particles on the surface of a small body upon contact with a spacecraft. Additionally, this rapid energy dissipation would imply that even hypervelocity impacts should perturb only the external layer of a self-gravitating aggregate on which segregation and other phenomena could take place. This would, in turn, produce a layered structure of which some evidence has been observed.
In vitro antibacterial effect of Pimpinella anisum essential oil on Enterococcus faecalis, Lactobacillus casei, Actinomyces naeslundii, and Aggregatibacter actinomycetemcomitans
Authors: Bakhshi Mahin , Kamalinejad Mohammad , Shokri Mehdi , Forouzani Gelareh , Heidari Faezeh , Tofangchiha Maryam
Published: October 2022

Introduction: Pimpinella anisum is a medicinal plant with antimicrobial, antifungal, and anti-oxidative properties. Limited studies have assessed the antibacterial properties of Pimpinella anisum on oral and dental pathogens.

Aim: This in vitro study aimed to assess the antibacterial effect of Pimpinella anisum essential oil on Enterococcus faecalis, Lactobacillus casei, Actinomyces naeslundii, and Aggregatibacter actinomycetemcomitans.

Materials and methods: After obtaining the essential oil of Pimpinella anisum, its antimicrobial activity was evaluated using the agar disc diffusion test. The minimum inhibitory concentration and minimum bactericidal concentration of the essential oil were also determined; 0.2% chlorhexidine was used as the positive control.

Results: The mean diameter of growth inhibition zone was 39 mm for Enterococcus faecalis, 40 mm for Lactobacillus casei, 42 mm for Actinomyces naeslundii, and 18.5 mm for Aggregatibacter actinomycetemcomitans. The mean diameter of the growth inhibition zones for Enterococcus faecalis, Lactobacillus casei, and Actinomyces naeslundii was significantly greater than that of Aggregatibacter actinomycetemcomitans (p=0.001). Also, the mean diameter of the growth inhibition zone of Actinomyces naeslundii was significantly larger than that of Enterococcus faecalis (p=0.05). The minimum inhibitory concentration and minimum bactericidal concentration of the essential oil for Enterococcus faecalis were 4.88% and 4.88%, respectively. These values were 9.76% and 9.76% for Lactobacillus casei, 9.76% and 4.88% for Actinomyces naeslundii, and 9.76% and 9.76% for Aggregatibacter actinomycetemcomitans, respectively.

Conclusions: Pimpinella anisum essential oil was effective against all four microorganisms evaluated in this study. Since the lowest minimum inhibitory concentration and minimum bactericidal concentration were recorded for Enterococcus faecalis, this essential oil has maximum effects on Enterococcus faecalis. Future clinical studies are required to assess the antimicrobial efficacy of Pimpinella anisum essential oil in clinical samples.
Normal appearing white matter metabolite pattern and sex differences in multiple sclerosis patients compared to healthy controls
Authors: Petrova Vasilena , Genov Krasimir
Published: October 2022

Introduction: Proton magnetic resonance spectroscopy (PrMRS) detects changes in brain metabolite levels in vivo.

Aim: The aim of the present study was to evaluate the brain metabolites choline ((Cho), creatine (Cr), and N-acetyl aspartate (NAA) in lesion free normal appearing white matter (NAWM) in patients with relapsing-remitting multiple sclerosis (RRMS) versus healthy controls. The second aim was to explore the impact of sex on brain metabolite changes.

Materials and methods: Fifty RRMS patients received PrMRS evaluation of their brain NAWM regions. The results were compared with the findings in 28 healthy demographically matched controls.

Results: We found elevated levels of Cho, Cr, and NAA in NAWM of MS patients in comparison with healthy controls. The NAA/Cr and Cr/NAA ratios were collated. A statistically significant difference between both groups was found only for NAA/Cr and Cr/NAA ratios. It is due to metabolite changes in the female MS patients.

Conclusions: The results of the present study using PrMRS proved metabolic changes in NAWM. Accompanying pathological process should be assumed, preceding plaques of demyelination. The gender impact needs further investigation.
Diagnosis and management of irritable bowel syndrome-like symptoms in ulcerative colitis
Authors: Dimitrova-Yurukova Desislava , Boyanov Nikola , Nakov Ventsislav , Nakov Radislav
Published: October 2022

Both ulcerative colitis (UC) and irritable bowel syndrome (IBS) are chronic gastrointestinal (GI) conditions that show some typical features. Persistent GI symptoms typical for IBS are observed in patients with diagnosed UC. Both IBS and UC are characterised by dysregulation of the enteric nervous system, alterations in the gut flora, low-grade mucosal inflammation, and activation of the brain-gut axis. Therefore, it appears that there may be some overlap between the two conditions. It is rather difficult to tell if the lower gastrointestinal symptoms are secondary to coexisting IBS or a hidden UC condition.

Given the disruptions in gut microbiota in UC and the likely role of the brain-gut axis in the production of such symptoms, treatments such as probiotics, fecal microbiota transplantation, antidepressants, and psychological therapy would appear to be sensible options to use in both illnesses. They are both chronic, causing patients to have a worse quality of life and everyday suffering, as well as incurring significant expenses for the health-care system.

The aim of this review article was to give an up-to-date perspective on the diagnosis and management of IBS-like symptoms in UC.
Clinical case of Bow Hunter's Syndrome
Authors: Ivanov N.
Published: October 2022

Bow Hunter‘s Syndrome (BHS) is a mechanical compression of the vertebral artery during head rotation, leading to partial disruption or complete interruption of the blood flow of the affected artery, causing vertebrobasilar vascular insufficiency. There are no established precise diagnostic and therapeutic behavioral algorithms in patients with BHS. I present a case of an 80-year-old woman with syncopal symptoms, in which a dynamic stenosis of the dominant left vertebral artery was diagnosed, and the same artery originates from the aortic arch with a separate ostium.
Double-blind validation of alternative wild bee identification techniques: DNA metabarcoding and in vivo determination in the field
Authors: Herrera-Mesías Fernanda , Bause Christopher , Ogan Sophie , Burger Hannah , Ayasse Manfred , Weigand Alexander M. , Eltz Thomas
Published: October 2022

Over the past few decades, several investigations around the globe have reported alarming declines in the abundance and diversity of bee species. The success of effective conservation strategies targeting these important pollinators relies heavily on accurate biodiversity assessments. The shortage of taxonomic experts and the escalation of the ongoing biodiversity crisis call for the development of alternative identification tools to implement efficient monitoring programs. The validation of such techniques is crucial to ensure that they provide results comparable to those of traditional morphotaxonomy. Here we performed two double-blind experiments to evaluate the accuracy of a pair of new techniques used for wild bee identification: DNA metabarcoding and in vivo identification in the field. The methods were tested on sets of wild bees from Germany and their results compared against evaluations done by panels of bee experts using traditional morphotaxonomy. On average the congruency of species identification between metabarcoding and morphotaxonomy was 88.98% across samples (N = 10), while in vivo identification and morphotaxonomy were 91.81% congruent (N = 7) for bees considered feasible for in vivo identification in the field. Traditional morphotaxonomy showed similar congruencies when compared to itself: 93.65% in the metabarcoding study and 92.96% in the in vivo study. Overall, these results support both new methods as viable alternatives to traditional microscopy-based assessment, with neither method being error-free. Metabarcoding provides a suitable option to analyze large numbers of specimens in the absence of highly trained taxonomic experts, while in vivo identification is recommended for repeated long-term monitoring, and when working in areas where the sampling of individuals could threaten local populations of endangered wild bee species. Further research is still needed to explore the potential of both techniques for conservation management and wildlife monitoring, as well as to overcome their current limitations as taxonomic tools.
The first recorded occurrence of the Asian hornet (Vespa velutina) in Ireland, genetic evidence for a continued single invasion across Europe
Authors: Dillane Eileen , Hayden Rachel , O'Hanlon Aidan , Butler Fidelma , Harrison Simon
Published: October 2022

The first record of the Asian/yellow-legged hornet (Vespa velutina) in Ireland was reported in April 2021, when a single female individual was discovered in Dublin. Vespa velutina has been present in mainland Europe since 2004 and in the UK since 2016 and poses an enormous threat to European apiculture and bee-mediated pollination services. Three mitochondrial genes were sequenced from the Irish specimen to determine whether the specimen originated from the established European population or signified a new point of entry from its native range in China. Additionally, specimens from Portugal, Spain, France, Germany, and the Channel Islands were sequenced at these three genes to build on previous studies which have asserted, based solely on Cytochrome Oxidase 1 (COI) analysis, that the entire range of V. velutina in Europe represents a single invasion which has proliferated since the first record in France. Further data were retrieved from GenBank for comparison. Results reveal that the mtDNA lineage observed in Dublin is the same as that seen throughout Europe, and therefore the arrival of this species in Ireland likely represents a further spread of the ongoing European invasion.
Panser la santé mondiale
Authors: Leterme Cédric
Published: October 2022

Malgré des progrès indéniables, l’accès universel à la santé est encore loin d’être une réalité pour les pays et les catégories de population les plus pauvres de la planète. En cause, un manque évident de personnel et de moyens sanitaires, mais aussi une vision trop souvent « humanitaire » de la santé qui en ignore les déterminants sociaux, politiques et économiques.
Panser la santé mondiale
Authors: Lima Barreto Mauricio , Bauvir Anne-Sophie
Published: October 2022

L’amélioration globale de certains indicateurs de la situation sanitaire dans le monde – comme l’espérance de vie – cache mal les inégalités abyssales qui subsistent ou s’accroissent entre les pays et entre les différents groupes sociaux en leur sein. Les voies de solution pour les réduire sont connues, mais la volonté politique manque pour les mettre en œuvre. Tour d’horizon des inégalités sanitaires mondiales et de leurs causes.
Panser la santé mondiale
Authors: Aloudat Tammam , Arjan Kirpalani Dena , Davis Meg , Dalbin Camille
Published: October 2022

Les politiques de santé mondiale et l’allocation asymétrique des ressources restent largement définies au Nord, par des institutions de gouvernance enracinées dans des épistémologies coloniales. L’appel à la décolonisation se fait dès lors de plus en plus pressant, mais il n’y a pas de recettes miracles en la matière. Rompre avec la colonialité de la santé mondiale appelle de profondes transformations qui dépassent le champ sanitaire.
Panser la santé mondiale
Authors: O’Higgins Celeste , Marty Jeremías , Bidelot Charline
Published: October 2022

Le système de santé cubain, nationalisé et centralisé à des fins d’accès égalitaire dès les lendemains de la révolution sociale et politique de 1959, affiche, malgré certaines limites importantes, parmi les meilleurs indicateurs sanitaires au monde. Combinée aux avancées technologiques des puissances capitalistes, sa généralisation à l’échelle de la planète permettrait à la santé d’atteindre des horizons jamais imaginés.
Panser la santé mondiale
Authors: Guttal Shalmali , Dalbin Camille , Bastin Jacques
Published: October 2022

En Asie, les régimes autoritaires ont profité de la pandémie pour asseoir davantage leur pouvoir. Et les mesures prises, en raison des politiques néolibérales de ces dernières décennies, ont aggravé la pauvreté des classes populaires. En réponse, des mouvements sociaux se mobilisent tant pour s’opposer aux discriminations et offrir des services aux plus précaires face à la maladie, que pour revendiquer le respect des droits humains.
Panser la santé mondiale
Authors: Grain
Published: October 2022

Les multinationales de la viande industrielle créent les conditions de pandémies, telle celle de la peste porcine qui a entraîné la mort de millions de porcs, et d’autres maladies qui peuvent se propager aux humains. Or, les solutions préconisées pour y faire face pénalisent les petites exploitations et permettent aux grandes entreprises de tirer profit de ces crises sanitaires et de renforcer leur contrôle sur l’approvisionnement mondial en viande.
Panser la santé mondiale
Authors: Vawda Yousuf , Bauvir Anne-Sophie
Published: October 2022

Les régimes de propriété intellectuelle des pays africains ont été façonnés par le passé colonial. D’où aujourd’hui encore, leur caractère inéquitable. L’Accord sur les aspects des droits de propriété intellectuelle qui touchent au commerce (ADPIC) permet certes une dérogation visant à contourner certaines protections dans la lutte contre le covid. Mais au-delà, une véritable décolonisation des questions de propriété intellectuelle s’impose.
Panser la santé mondiale
Authors: Collectif d’auteur·trices de l’Afri  , Bidelot Charline
Published: October 2022

La souveraineté sanitaire repose sur la capacité des États à assurer le droit à la protection de la santé, inscrit dans de nombreuses constitutions. La pandémie de covid-19 a mis en évidence les défaillances des systèmes de santé africains et l’urgence d’y remédier, en investissant notamment dans la recherche et l’innovation. Les défis sont de taille, mais la crise pourrait être un élément déclencheur pour de nouvelles politiques de santé.
Social Media Presence Is Associated With Diversity and Application Volume for Orthopedic Surgery Residency Programs
Authors: Wang Kevin Y. , Puvanesarajah Varun , Suresh Krishna V. , Xu Amy L. , Ficke James R. , LaPorte Dawn , Kebaish Khaled M.
Published: October 2022

The purpose of this study was to assess the association between social media presence (Twitter and Instagram), diversity in orthopedic surgery residency programs, and the number of applications received by a program. Data from Twitter and Instagram for 179 orthopedic residency programs accredited by the Accreditation Council for Graduate Medical Education were collected, including the presence of a social media account, date of first post, number of posts, and number of followers. Residency program data were collected from the Association of American Medical Colleges Residency Explorer Tool and included percentage of Whiteresidents, percentage of male residents, residency ranking, and number of applications submitted during the 2019 application cycle. Bivariate and multivariable analyses were performed with adjustment for program ranking. Of 179 residency programs, 34.6% (n=62) had Twitter, and 16.7% (n=30) had Instagram. Overall, 39.7% (n=71) had a social media presence, defined as having at least one of the two forms of social media. Programs with social media presences had higher average rankings (48.1 vs 99.6 rank,
P
<.001). After adjusting for program ranking, social media presence was associated with increased applications during the 2019 application cycle (odds ratio [OR]=2.76,
P
=.010). Social media presence was associated with increased odds of gender diversity (OR=3.07,
P
=.047) and racial diversity (OR=2.21,
P
=.041). Individually, Twitter presence was associated with increased odds of gender (OR=4.81,
P
=.018) and racial diversity (OR=4.00,
P
=.021), but Instagram was not (
P
>.05). Social media presence is associated with more residency program applications and increased resident diversity. Social media can be used to highlight inclusivity measures and related opportunities. [
Orthopedics
. 2023;46(1):47–53.]
Femoral Discrepancy After Childhood Bone Sarcoma Surgery Can Be Treated With Magnetic Intramedullary Nails
Authors: Alpan Bugra , Eralp Levent , Sungur Mustafa , Valiyev Natig , Özger Harzem
Published: October 2022

This study aims to determine whether femoral lengthening with a magnetic motorized intramedullary nail (PRECICE; NuVasive) is safe and effective in patients with discrepancy due to limb salvage performed for bone sarcomas before skeletal maturity. Six patients (male, 4; female, 2) with a mean age of 9.3 years (range, 4.8–12.8 years) at the time of index limb salvage surgery were retrospectively analyzed. Four patients had undergone biological reconstruction with liquid-nitrogen recycled frozen autograft shell and inlaid vascular fibula combination and 2 had undergone nonbiological reconstruction with distal femur modular tumor endoprosthesis. The mean age at PRECICE operation was 16.1 years (range, 13.4–20.1 years). The mean prelengthening femoral discrepancy was measured as 60 mm (range, 39–80 mm). Lengthening was achieved in 5 of these 6 patients. Although the PRECICE nail was successfully implanted in the sixth patient, lengthening could never be performed owing to failure to overcome the chronic diaphyseal nonunion first, as intended with compressive use of the nail. For the other 5 patients, in whom lengthening was performed, the mean lengthening was 45 mm (range, 35–52 mm), the mean ratio of achieved to planned lengthening was 93% (range, 74%–100%), and the mean bone-healing index was 41 days per cm (range, 24–69 days per cm). Mean Musculoskeletal Tumor Society score improved from 25.6 to 27.2 after lengthening. No major complications occurred. The outcomes of this study demonstrate that the PRECICE implant can safely and effectively correct femoral length discrepancy caused by limb salvage performed for osteosarcoma before skeletal maturity. [
Orthopedics
. 2023;46(1):27–34.]
Midterm Results of Contemporary Uncemented Total Hip Arthroplasty in Patients 45 Years or Younger
Authors: Hernandez Nicholas , Kim Billy , Cochrane Niall H. , Ryan Sean P. , Seyler Thorsten M.
Published: October 2022

Total hip arthroplasty (THA) in young patients has varying results, and some reports show inferior results when compared with those of older patients. This study evaluated the outcomes of contemporary uncemented THA in patients 45 years or younger. This was a retrospective review from 2003 to 2015 at an academic institution. Three hundred one uncemented THAs in 232 patients 45 years or younger were evaluated. All patients had a minimum follow-up of 5 years. Ninety-day complications, survivorship free of revision, and dislocations were evaluated. Mean age was 35.7 years, 43.1% of patients were women, and mean follow-up was 9.3 years. Ninety-day complications included 26 emergency department visits, 11 readmissions, 3 revisions, and 3 dislocations. The rate of 10-year survivorship free of revision was 85.5%, and the rate of 10-year survivorship free of aseptic revision was 87.7%. Excluding metal-on-metal (MOM) THAs, 10-year aseptic survivorship was 93.3%. The most common reasons for revision were adverse local tissue reaction after MOM THA (16 hips) and periprosthetic joint infection (6 hips). In a multivariable logistic regression model, sickle cell disease (SCD) and conversion THA were associated with 90-day readmissions. Both MOM THA and SCD were associated with revision (
P
<.05). Patients who are 45 years or younger undergoing THA (excluding MOM articulation) had a rate of 10-year survival free of aseptic revision of 93.3%. At 9.3 years' mean follow-up, THA in young patients was associated with low revision rates with acceptable risk of prosthetic joint infection and dislocation. Patients with SCD are at increased risk for early readmission and revision at latest follow-up. [
Orthopedics
. 2023;46(1):e45–e51.]
Temperature prediction and analysis based on improved GA-BP neural network
Authors: Zhang Ling , Sun Xiaoqi , Gao Shan
Published: October 2022

In order to predict the temperature change of Laoshan scenic area in Qingdao more accurately, a new back propagation neural network (BPNN) prediction model is proposed in this study. Temperature change affects our lives in various ways. The challenge that neural networks tend to fall into local optima needs to be addressed to increase the accuracy of temperature prediction. In this research, we used an improved genetic algorithm (GA) to optimize the weights and thresholds of BPNN to solve this problem. The prediction results of BPNN and GA-BPNN were compared, and the prediction results showed that the prediction performance of GA-BPNN was much better. Furthermore, a screening test experiment was conducted using GA-BPNN for multiple classes of meteorological parameters, and a smaller number of parameter sets were identified to simplify the prediction inputs. The values of running time, root mean square error, and mean absolute error of GA-BPNN are better than those of BPNN through the calculation and analysis of evaluation metrics. This study will contribute to a certain extent to improve the accuracy and efficiency of temperature prediction in the Laoshan landscape.
Precise large deviations of aggregate claims in a nonstandard risk model with arbitrary dependence between claim sizes and waiting times
Authors: Gao Qingwu , Pan Wenlei
Published: October 2022

Recently, Chen et al.[3] investigated the precise large deviations of aggregate claims in a renewal risk model with arbitrary dependence between claim sizes and their waiting times. In this paper, we extend their results to a nonstandard risk model in which various dependence structures are imposed on the modeling components, and obtain the asymptotic lower and upper bounds of precise large deviations for aggregate claims, which hold uniformly for all $ x $ in a $ t $-interval.
Managing bed capacity and timing of interventions: a COVID-19 model considering behavior and underreporting
Authors: Mendoza Victoria May P. , Mendoza Renier , Ko Youngsuk , Lee Jongmin , Jung Eunok
Published: October 2022

We develop a mathematical model considering behavioral changes and underreporting to describe the first major COVID-19 wave in Metro Manila, Philippines. Key parameters are fitted to the cumulative cases in the capital from March to September 2020. A bi-objective optimization problem is formulated that allows for the easing of restrictions at an earlier time and minimizes the number of additional beds ensuring sufficient capacity in healthcare facilities. The well-posedness of the model and stability of the disease-free equilibria are established. Simulations show that if the behavior was changed one to four weeks earlier before the easing of restrictions, cumulative cases can be reduced by up to 55% and the peak delayed by up to four weeks. If reporting is increased threefold in the first three months of the estimation period, cumulative cases can be reduced by 61% by September 2020. Among the Pareto optimal solutions, the peak of cases is lowest if strict restrictions were eased on May 20, 2020 and with at least 56 additional beds per day.
Modified UNet++ with atrous spatial pyramid pooling for blood cell image segmentation
Authors: Lan Kun , Cheng Jianzhen , Jiang Jinyun , Jiang Xiaoliang , Zhang Qile
Published: October 2022

Blood cell image segmentation is an important part of the field of computer-aided diagnosis. However, due to the low contrast, large differences in cell morphology and the scarcity of labeled images, the segmentation performance of cells cannot meet the requirements of an actual diagnosis. To address the above limitations, we present a deep learning-based approach to study cell segmentation on pathological images. Specifically, the algorithm selects UNet++ as the backbone network to extract multi-scale features. Then, the skip connection is redesigned to improve the degradation problem and reduce the computational complexity. In addition, the atrous spatial pyramid pooling (ASSP) is introduced to obtain cell image information features from each layer through different receptive domains. Finally, the multi-sided output fusion (MSOF) strategy is utilized to fuse the features of different semantic levels, so as to improve the accuracy of target segmentation. Experimental results on blood cell images for segmentation and classification (BCISC) dataset show that the proposed method has significant improvement in Matthew's correlation coefficient (Mcc), Dice and Jaccard values, which are better than the classical semantic segmentation network.
E-Book with Problem Based Learning to Improve Student Critical Thinking in Science Learning at Elementary School
Authors: Susanto Teguh Trianung Djoko , Dwiyanti Putri Bestari , Marini Arita , Sagita Julius , Safitri Desy , Soraya Evitha
Published: October 2022

With the development of technology, especially in the world of education, teachers must have learning media that attracts students' attention, one of which is E-Books. This study aims to determine whether Problem Based Learning-Based E-Books Can Improve Students' Critical Thinking Ability in Primary School Science Learning. This research was conducted on elementary school students in the district of Jagakarsa, South Jakarta. This research method uses the RnD method. In this research. To get the results, the researchers used a pre-test and also a post-test to get the results. The results show that this E-Book is able to improve critical thinking skills in science learning as digital media innovation, narration, video and also practice questions.
Advancing STEM Education and Innovation in a Time of Distance Learning
Authors: Yu Poshan , Liu Liang , Sampat R. Michael , Mandizvidza Kudzai , Lu Shengyuan
Published: October 2022

STEM education is a multidisciplinary teaching approach that aims at helping students develop knowledge in science, technology, engineering, and mathematics. This chapter aims to study the development of online STEM education of K12 group and its innovation in the era of distance education and popularity in China. This chapter will discuss the current situation of STEM education in China and the factors affecting the implementation of it particularly during the COVID-19 period. This chapter will study the learning outcome of K12 group by investigating the impact of STEM education on teaching mode. This chapter will discuss whether and how STEM approach would enhance teaching quality on K12. By applying bibliometric analysis, the chapter will perform statistical and correlation analysis on the STEM education. STEM and STEAM cases will be used for discussion. Finally, the chapter will provide suggestions for stakeholders to promote STEM education.
Differentiation for the Gifted
Authors: Avcı Doğan Gülşah
Published: October 2022

This chapter aims to recommend the Differentiated Hybrid Education Model for the gifted and a differentiation proposal for STEM education. Differentiation is examined along with educational models and strategies in gifted education. Effective differentiation methods and techniques in the field are constantly being renewed. These renovations include the use of technological instruments and technology-based program designs in education. As forms of technology-based environments, distance and online education are the models that are rarely used under normal conditions have become a necessity with the pandemic period. This period naturally created an opportunity for distance-online education to be seen as a differentiation strategy for the gifted. STEM, which is an effective approach in the education of the gifted, stands out as a good example that can be adapted to the Differentiated Hybrid Education Model.
Increasing Women's Chances in STEM Fields and Combating Challenges
Authors: Harris Karleah , Le Kieu Ngoc , Yunusa Vakkia Roseline Jindori , Ofori Afua Nyarkoa
Published: October 2022

Research has shown the challenges women face in the STEM fields, even though there are benefits. Therefore, knowing the challenges can help better prepare females for careers in STEM and help with policymaking. In this chapter, the authors have highlighted the impact of remote learning in STEM and how to increase women's representation and STEM on college students. They recognize that interventions are needed to help recruit and retain women in STEM fields, and female role models are required. Therefore, having a diverse workforce culture is vital, and removing the gender stereotypes associated with women in STEM is critical for the future of women's interest and employment in STEM fields.
New Challenges to Teaching Technical Disciplines in Architecture Schools
Authors: del Ama Gonzalo Fernando , Zannoni Allison L. , Fowler Paul , Danesh Mohammadmehdi , Paley Donna
Published: October 2022

The goal of teaching zero energy building design in architecture schools has to be tackled by different approaches, from design disciplines to building science, combining traditional and new teaching methods. Current curricula at architecture schools are trying to introduce design courses according to the so-called integrated energy design. This chapter studies current building science and technology teaching strategies, examples of student work at Keene State College in New Hampshire (US), the competencies acquired in each course, and the impact of the technical disciplines on design studios. Finally, the impact of building information modeling (BIM) and building performance simulation (BPS) on the teaching of technical disciplines in architecture programs are evaluated. The essential goal of this chapter is to determine and establish some techniques for using BIM and BPS as adequate tools to teach sustainable building design and construction.
Play's Continuum of Needs
Authors: Vilas Deborah Brewster
Published: October 2022

Optimal healing for children in hospitals occurs when their developmental needs are considered as part of their overall treatment plan. One of the most pressing developmental needs for all children is the need to play, and this remains so even when they are confined to a hospital bed or face developmental delays or disabilities. This chapter examines the most basic components of implementing play programs in hospitals, such as the intentional creation of space for play, determining the best times for children to play, and exploring what types of play are therapeutic and possible in a hospital environment. The author presents a continuum that highlights foundational components of a therapeutic play program and explores a wide range of types of play, including examples that arise from a variety of cultures. Child life specialists and hospital play specialists are in a unique position to improve patient experiences and health outcomes by interacting with children using their primary language: the language of play.
Building Socio-Emotional Skills Through Play to Cope With Hospitalization
Authors: Failo Alessandro , Taverna Livia , Sangiuliano Intra Francesca , Brighi Antonella
Published: October 2022

This chapter highlights the possible benefits of applying the social emotional learning model to play strategies for hospitalized children as a leverage to promote children's adaptive coping responses and development. Social and emotional learning can be viewed as a process of developing and using those skills required for identifying and regulating emotions, essential in maintaining a sense of self-identity, fostering positive relationships, feeling and displaying empathy for others, making choices, finding ways to solve problems and achieve personal and collective goals. Although the study regarding this cluster of life-evolving skills and its developmental implications has been mainly focused on the school context, in this chapter, the authors aim to present fruitful application to the hospital context, where social and emotional competence may support children when coping with a stressful phase of their lives; according to this perspective, a significant emphasis will be placed on promoting a systemic approach that encourages several factors for promoting children' adjustment.
Gendering Play, Producing Bodies
Authors: Munia Rafael
Published: October 2022

This chapter will discuss the potential consequences of gendered narratives in children's play with a particular focus on play specialism strategies. It aims to demonstrate to the reader how objects, materials, practices, and discourses when gendered can affect the ways in which boys and girls imagine their bodies and what they can do. This chapter will first introduce the way objects are gendered with rigid discourses of masculinity and femininity. In terms of theoretical approach, this chapter borrows from contributions made by neo-materialist feminists in the field of material anthropology. In doing so, it will argue that objects and materials such as toys, books, games, costumes, and movies are not passive and inactive until animated by human action and interaction but are themselves agents with the potential for gender play and practice.
Play in Children With Autism Spectrum Disorder
Authors: Bentenuto Arianna , Perzolli Silvia , de Falco Simona , Venuti Paola
Published: October 2022

During play activities, children express behaviors, emotions, ways of thinking and learning, as well as social skills, desires, and fears. Differences in the play of children with ASD appear during the first year of life and remain during development. Impairment in symbolic play constitutes one of the most relevant clinical aspects observed during a clinical assessment in young children. However, caregiver involvement in child activities enhances the frequency, duration, and complexity of child play. Given the importance for children with ASD to maintain routines and stability, hospitalization constitutes a challenging moment since they are removed from their familiar environment. In this chapter, the focus will be on the characteristics of play of children with ASD during interaction with caregivers, and on the attention to be used in the context of hospitalization.
Integrating Knowledge-Driven and Data-Driven Methodologies for an Efficient Clinical Decision Support System
Authors: Obot Okure Udo , Attai Kingsley Friday , Onwodi Gregory O.
Published: October 2022

Clinical decision support systems (CDSSs) symbolize a significant transformation in healthcare delivery. CDSS enhances healthcare delivery by enabling personnel in medical institutions to handle complex decision-making processes with great speed and high accuracy. Decision support systems are developed using a knowledge-driven or data-driven approach, although both approaches seem to complement each other. For instance, while data-driven is an objective approach, the knowledge-driven approach is subjective. The objective of the chapter is to elaborate on the integration of data-driven and knowledge-driven methodologies for clinical decision support systems. An overview of data-driven and knowledge-driven approaches is presented with a review of both current and dated literature on the subject with numerous viewpoints to support the discussion. Based on the findings, a promising methodology is proposed that integrates data-driven and knowledge-driven approaches and is believed to overcome the challenges of the individual approaches.
Human-Centred Acoustic Detection for Smartphone Application in Healthcare
Authors: Qu Yuanying , Wang Xingheng , Yu Limin , Zhu Xu , Wang Wenwu , Wang Zhi
Published: October 2022

In acoustic sensing techniques, acoustic sensors use the main functionality, namely recording and playing the sound, to explore related research and achieve various applications along with novel user experiences. Acoustic sensing is developed in the research, where human-centred research is a vital branch. Human-based research is crucial to healthcare with excellent privacy protection and long-term support. This chapter presents a comprehensive illustration of human-centred acoustic sensing focusing on two innovative dimensions: vertical direction and horizontal direction, to illustrate and analyse the latest developments. In addition, smartphone-based applications and deep learning approaches are systematically described. This chapter also analyses existing technology, predicts its development trend and provides constructive suggestions for future research.
Review of Machine Learning for Bioimpedance Tomography in Regenerative Medicine
Authors: Liu Zhe , Chen Zhou , Yang Yunjie
Published: October 2022

Monitoring cell growth and activities is crucial for regenerative medicine. Although optical imaging can provide high resolution, such methods are limited by the penetration depth. Bioimpedance tomography is an alternative way as it can overcome the penetration problem and possess the advantages of non-radiative, non-destructive, and high temporal resolution. In addition, with the rapid development of machine leaning, learning-based bioimpedance tomography is gradually introduced into regenerative medicine and demonstrates powerful potential. This chapter aims to provide an overview of the state-of-the-art machine learning methods of bioimpedance tomography in regenerative medicine while offering perspectives for future research directions. This chapter first summarizes the electrical properties of tissues and the principle of electrical impedance tomography (EIT) then extensively reviews the recent progress on learning-based single-modal and multi-modal imaging methods of EIT for regenerative medicine. Finally, promising future research directions are discussed.
Design of Drug Dosage Regimen (DDR) for Immune Thrombocytopenic Purpura (ITP) Patients Using Control Theory Concepts
Authors: Rajkumar K  , Narayanan S. , Natarajan Sivakumaran
Published: October 2022

In this chapter, an optimal drug dosage regimen is designed by incorporating the standard treatment guidelines in terms of average and safe limits of drug dosage for immune thrombocytopenic purpura patients (ITP). If constant drug dosage is administered with fixed dosing, the interval leads to sustained oscillations of platelet count values with higher magnitude. Moreover, the amount of dose utilized for the treatment is also high. This leads to undesirable consequences which are dangerous to patients. Hence, a composite framework is essential to obtain optimal drug dosage for specific ITP patients. This chapter presents the potential benefits of the pharmacokinetic-pharmacodynamic (PK/PD) model of ITP patients and its applicability to obtain the optimum dosage profile using linear control theory in line with standard guidelines. Prediction of dosage interval is made for a specific patient using this PK/PD model. And this information is given to the controller framework as sampling time.