bluuebunny/crossref_metadata_2025 huggingface dataset:
Praktik Pembiayaan Mudharabah dan Musyarakah terhadap Profitabilitas Bank Umum Syariah di Indonesia
Authors: Aulia Fena Ulfa , Nabila AJ Elda Ayu
Published: November 2021

Penelitian ini bertujuan untuk mengetahui dampak pembiayaan mudharabah dan pembiayaan musyarakah terhadap profitabilitas bank umum syariah di Indonesia (Periode 2017-2019). Dalam penelitian ini menggunakan pendekatan kuantitatif dengan jenis penelitian asosiatif. Popolasi yang digunakan adalah seluruh Bank Umum Syariah yang terdaftar di Indonesia. Teknik pengambilan sampel yaitu  dengan menggunakan teknik Simple Random Sample. Teknik analisis data menggunakan uji asumsi klasik (uji normalitas, uji autokorelasi, uji heteroskedastisitas, uji multikolinearitas), uji analisis persamaan regresi linear berganda, dan uji statistik (uji t, uji F dan uji koefisien determinasi). Hasil penelitian menunjukkan bahwa pembiayaan mudharabah dan pembiayaan musyarakah secara simultan berpengaruh signifikan dan positif terhadap profitabilitas (ROA). Hasil pengujian secara parsial menunjukkan bahwa pembiayaan mudharabah berpengaruh signifikan dan positif terhadap profitabilitas (ROA), sedangkan pembiayaan musyarakah berpengaruh signifikan dan negatif terhadap profitabilitas (ROA)
Analisis Determinan Rating Sukuk Korporasi Di Indonesia
Authors: Faruq Umarul
Published: November 2021

Penelitian ini bertujuan untuk mengumpulkan bukti empiris dan mengetahui signifikansi pengaruh maturitas, ukuran perusahaan, pertumbuhan, profitabilitas, likuiditas, dan leverage terhadap peringkat sukuk perusahaan di Indonesia, serta menguji teori tentang determinan peringkat sukuk. Populasi dalam penelitian ini adalah seluruh sukuk korporasi di Indonesia yang telah diperingkat oleh Pefindo. Teknik pengambilan sampel dalam penelitian ini menggunakan metode purposive sampling dengan jumlah sampel sebanyak 124 sukuk yang diterbitkan oleh 26 perusahaan pada periode 2014-2018. Metode pengumpulan data menggunakan pendekatan studi pustaka. Teknik analisis data menggunakan Structural Equetion Modeling dengan Partial Least Square menggunakan software SmartPLS 3.0. Hasil penelitian ini menunjukkan bahwa variabel ukuran perusahaan, pertumbuhan, dan likuiditas masing-masing berpengaruh positif signifikan terhadap peringkat sukuk, sedangkan variabel leverage berpengaruh negatif signifikan terhadap peringkat sukuk. Variabel profitabilitas dan maturitas tidak berpengaruh signifikan terhadap peringkat sukuk.
Method of verifying the emission level of the exhaust components of a special
vehicle in relation to EURO III standard in road conditions
Authors: Matla Jędrzej , Kaźmierczak Andrzej
Published: November 2021

The following article presents the method of verification of EURO III standard in real life conditions for special vehicles. The test object qualified as a special vehicle of N3G category was tested in road conditions along a defined route, and then the obtained measurement results were compared to the exhaust emission standard (EURO III) applicable for this vehicle in transient testing mode. A method of comparing the emission factors in road conditions with the indicators obtained on the engine dynamometer was proposed. An AVL mobile exhaust gas analyzers (PEMS) dedicated for the Real Driving Emissions (RDE) road tests were used in the research.
Raising Awareness about Adult Autism Spectrum Disorder
Authors: Teodoro Tomás , Salgado José
Published: November 2021

N/a.
Há Artefactos e Artefactos
Authors: Baptista Diogo , Froes Filipe
Published: November 2021

N/a.
Percutaneous two unilateral iliosacral S1 screw fixation for pelvic ring injuries: a retrospective review of 38 patients
Authors: Son Whee Sung , Cho Jae-Woo , Kim Nam-Ryeol , Cho Jun-Min , Choi Nak-Jun , Oh Jong-Keon , Kim HanJu
Published: November 2021

Purpose: Percutaneous iliosacral (IS) screw fixation for pelvic ring injuries is a minimally invasive technique that reduces the amount of blood loss and shortens the procedure time. Moreover, two unilateral IS S1 screws exhibit superior stability to a single IS screw and are also safer for neurological injuries than an S2 screw. Therefore, this study aimed to evaluate fixation using percutaneous two unilateral IS S1 screws for pelvic ring injuries and its subsequent clinical outcomes. Methods: We retrospectively reviewed 38 patients who underwent percutaneous two unilateral IS S1 screw fixation for pelvic ring injuries. The procedure time, blood loss, achievement of bone union, radiological outcomes (Matta and Tornetta grade), and postoperative complications were evaluated. Results: The mean procedure time, hemoglobin loss, bone union rate, and time to union were 40.1 minutes (range, 18–102), 0.6 g/dL (range, 0.3–1.0), 100%, and 153.2 days (range, 61–327), respectively. The Matta and Tornetta grades were excellent, good, and fair in 24 (63.1%), 11 (28.9%), and 3 patients (7.9%), respectively, and the postoperative complications were S1 screw loosening, widening of the symphysis pubis (2.3 and 2.5 mm), lumbosacral plexopathy, and S1 radiculopathy in one (2.6%), two (5.3%), one (2.6%), and one patient (2.6%), respectively. However, all neurological complications recovered spontaneously. Conclusions: Percutaneous two unilateral IS S1 screw fixation was useful for treating pelvic ring injuries. In particular, it involved a short procedure time with little blood loss and also led to 100% bone union and good radiological outcomes.
Immunomodulator Effect of Lemongrass Extract (Cymbopogon nardus L.) to Increase Immune Cells as a Precaution Against SARS-CoV-2
Authors: Setiyowati Putri Ayu Ika , Solekha Rofiatun , Negara Sri Bintang Sahara Mahaputra Kusuma , Rosalina Reny
Published: November 2021

Introduction: In humans, Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2) can damage some tissue when the immune systems was decrease. Natural product from the plant often used to improve immune response against microorganism including virus. This study aimed to determine the potential antioxidant of lemongrass extract (C . nardus) with various dosage that can provide immunomodulatory effects and find an optimal dosage to be used.  Methods: The method used observasional analytic, using animal model of 30 male mice strain BALB/C, weight 25-30 gram, divided into 5 groups; the positive control group was given 0.05 mL of  0.05% CMC within 14 days, negative control group was given IMBOOST® tablet 200 mg/kg body weight (bw) within 14 days, treatment groups  were given C. nardus extract with various doses 50 mg/kg bw, 150 mg/kg bw, and 300 mg/kg bw.  In day 21 all group were injected with 0,2 ml of  pathogen bacterial (S. aureus). Blood samples were taken three times: 7th day, 14th day, and 21th day. Results: The results showed that lemongrass extract (C. nardus) was able to influence the leukocyte and lymphocytes count with significant different (p<0.05). The optimal dose is 150 mg/kg body weight. Conclusion: The antioxidant compounds that contain in the C. nardus extract have an ability to increasing the immune system in the dose 150 mg/kg bw , but in the dose 300 mg/kg bw became toxic that can make a skin injury or death in animal test.
Prenatal Risk Factors on Children’s Cerebral Palsy Case at RSIA Bunda Jakarta
Authors: Lariza Banatul Banatul , Artanti Kurnia Dwi , Hidayat Taufiq Taufiq
Published: November 2021

Introduction: Cerebral Palsy is a disease that is less recognized by the public due to the lack of information related to CP in Indonesia. Aims to analyze prenatal risk factors that influence the evidence of CP RSIA Bunda Jakarta.Methods: This study was conducted in April 2021 at RSIA Bunda Jakarta, an analytical study with a case control design. The sample in this study were 124 respondents from mothers of children who underwent outpatient treatment at the RSIA Bunda Jakartaas cases and controls. each taken by simple random sampling technique. Data were analyzed using the test chi-square to analyze the relationship between variables.Results: The results of statistical analysis showed that the risk factors associated with the incidence of CP were maternal age (p= 0.00; OR= 13.25; 95% CI= 2.93-59.93), preeclampsia (p= 0.00; OR= 2,06; 95% CI= 1,71-2,48), TORCH (p= 0.00; OR= 2.40; 95% CI= 1.92-3.01), and antenatal care (p= 0.00; OR= 41.2; 95% CI= 5.45-317.0). Conclusion: Risk factors affecting the occurrence of CP in children include age <20 or ≥35 years, preeclampsia, TORCH infection and antenatal care visits <4 times. It is necessary to increase intervention programs at various levels of health services to diagnose and prevent the occurrence of cerebral palsy in children so that optimal maternal and child health is achieved. and further research is needed to determine other risk factors that can cause CP in children such as perinatal and postnatal risk factors.
Caregiver Burden And Psychosocial Factors In Mothers With Autism Spectrum Disorder Children
Authors: Fithriyah Izzatul , Carrasco Magdeline Elizabeth
Published: November 2021

Introduction: Burden experienced by mother can delayed the success of therapy to ASD children. This study aims to determine the correlation of psychosocial factors and caregiver burden in mothers with ASD children.Methods: This study was a cross-sectional analytic study on mothers with ASD children at the Children's Daycare Dr.Soetomo General Hospital. The research instrument used sociodemographic questionnaire and a Caregiver Burden Assessment (CBA). Results: This study was followed by 26 mothers with ASD children. Results: The results showed that 50% of mothers experienced moderate burdens and 34% experienced severe burdens. The results of the correlation analysis showed a significant relationship between caregiver burden and maternal age (p<0.05, r=0.316) and child age (p<0.05, r=0.274). Support and assistance from others in caring for GSA children also correlated with the mother's caregiver burden (p<0.05, r=0.118). Maternal caregiver burden is not correlated with marital status, education level, occupation, and economic status. Conclusion: Mothers with ASD children experience a psychological burden while caring for ASD children. Psychosocial support and assistance from the environment are urgently needed to reduce the caregiver burden on mothers so that they can improve the outcomes of interventions and therapy for children with ASD.
Antibacterial mechanism of Kratom (Mitragyna speciosa) methanol extract on Streptococcus pneumoniae and Eschericia coli bacteria
Authors: Salim Hotimah Masdan , Puspitarini Marinda Dwi , Setiwati Yuani , Shimabukuro Michio
Published: November 2021

Introduction: Kratom (Mitragyna speciosa) is a tropical herbal plant native to the North Malay Peninsula, Malaysia and Thailand. In Indonesia, kratom us a typical plant of West Kalimantan, especially in Putussibau. Kratom leaf has many pharmacological effects, one of them is antioxidant. However, the antioxidant and antimicrobial activities of Mitragyna speciosa leaf extracts are lacking. This study was to examine the effect of the methanol extract of Mitragyna speciosa (Rubiaceae Family) leaves on microorganisms Escherichia coli and Strepococcus pneumoniae.Methods: Kratom leaves were extracted with methanol as solvent. In this study, S. pneumoniae and E. coli bacteria have been used. Antibacterial activity tests were carried out at concentrations of 0.78%, 1.56%, 3.125%, 6.25%, 12.5%, 25%, 50% and 100%. Insilico was used to search for secondary metabolites and metabolite interactions in Mytragina speciosa. Results: Mitragyna speciosa leaf methanol extract was effective in inhibiting the growth of E. coli and S. pneumoniae significantly (P<0.001). The growth of e.coli was not identified from a concentration of 25% to 100%. However, there was no bacterial growth in S. pneumoniae from a concentration of 6.25% to 100%. In the insilico study it was found that the secondary metabolite of Mitragyna speciosa is quercetin, which interacts with the ATP1 protein as a predictor in the mechanism of Mitragyna speciosa as an antibacterial. Conclusion: In conclusion, there is no correlation between nutritional status and remission outcome of patients with ALL in the induction phase of therapy. However, high percentage of underweight patients shows nutrition needs special attention to improve therapy outcomes.
A Systematical Review of The Effect of Ketogenic Diet on Bcl-2 (B-cell lymphoma-2) Expression as An Apoptosis Marker in Cancer Treatment
Authors: Kusuma Vania Islamey , I’tishom Reny , Qurnianingsih Ema , Rejeki Purwo Sri
Published: November 2021

Introduction: Ketogenic diet seems to be in a great demand nowadays as a lot of people are interested in adopting it into their lifestyle. It is also found that the ketogenic diet shows several beneficial effects including cancer prevention. However, the detail mechanism still remains unknown. Therefore, this review was aimed to find out the effect of ketogenic diet on Bcl-2 (B-cell lymphoma-2) expression in cancer.Methods: We searched published literatures in PubMed through 2011-2020 using specific keywords. The literatures were filtered according to inclusion and exclusion criteria. Animal model, total sample size, underlying condition/inflammatory process occurs, details of the intervention/diet including diet contents in control group and high-fat group, and the duration of the intervention, Bcl-2 results, and p-value were extracted.Results: 7 studies were included in this review. Bcl-2 expression found decrease in 5 out of 6 studies. Similar result also obtained in Bcl-2 protein level, which measured by western blot. Bcl-2 protein level shows a decrease in 2 out of 3 studies.Conclusion: This review shows that high-fat diet that contained in ketogenic diet most likely lead to decrease in Bcl-2 expression. Therefore, indicating the ability of ketogenic diet to affect cancer progression by inducing apoptosis process.
Strategi Inovasi Dinas Perpustakaan dan Arsip Kabupaten Banggai Untuk Meningkatkan Budaya Literasi Masyarakat
Authors: Samsara Ladiatno
Published: November 2021

Budaya literasi belum sepenuhnya familiar di kalangan masyarakat. Melalui tulisan ini digambarkan strategi inovasi untuk meningkatkan budaya literasi masyarakat Kabupaten Banggai, Provinsi Sulawesi Tengah. Metode penelitian kualitatif dengan studi literatur dan lapangan dijadikan sebagai pilihan dalam menggambarkan strategi untuk meningkatkan budaya literasi masyarakat di Kabupaten Banggai. Strategi inovasi yang diimplementasikan terkait pengelolaan perpustakaan dengan jaringan yang luas; memiliki akses cepat, tepat dan mampu memberikan pelayanan secara maksimal; kebaruan ditekankan pada media pencarian dan perilaku pemustaka; perpustakaan keliling di lokasi wisata; pojok simputnyo dan arsip digital. Selain strategis tersebut, dukungan pemimpin dalam peningkatan budaya literasi menjadi salah satu lngkah agar budaya literasi di Kabupaten Banggai meningkat.Literacy culture not yet familiar among the community. This papper describe innovation strategy to increase literacy culture people in Bangga Regency, Central Sulawesi Province. Qualitative research method with literature and field study choices to describe innovation strategy to increase literacy culture people in Bangga Regency. Innovation strategy can describe: library manage with an extensive network connection, have a fast access, precise and able to provide maximum service; innovation focus in searching tools and librarian habit; mobile library in tourist site; pojok simputnyo and digital archive. Non only the strategies, but also sipport of leaders for increase literation culture can made one of strategy to increase literacy culture in Banggai Regency.
Eliminasi Kesenjangan Kualitas SDM Melalui Kebijakan Afirmasi Pendidikan di Jawa Timur
Authors: Ali Madekhan
Published: November 2021

Kesenjangan kualitas sumberdaya manusia antar wilayah merupakan gejala umum pembangunan daerah, tidak terkecuali Jawa Timur. Selain diperlukan penguatan sinergi sumberdaya pemerintah, masyarakat sipil dan sektor swasta, untuk memastikan eliminasi ketertinggalan wilayah pinggiran dengan wilayah pusat, diperlukan pula implementasi kebijakan afirmasi. Tujuan kajian ini untuk memformulasi kebijakan afirmasi pendidikan dalam rangka eliminasi Kesenjangan Kualitas SDM, sesuai kapasitas sumberdaya dan tingkat kewenangan Pemerintah Provinsi Jawa Timur. Melalui metode studi dokumen diperoleh gambaran bahwa kinerja pertumbuhan ekonomi 2019 Jawa timur termasuk tinggi 5,52%, namun masih diikuti tingginya angka kemiskinan 10,37%. Rata-rata lama sekolah penduduk masih 8,21 tahun, atau setara kelas dua SMP sederajat. Dari 38 Kabupaten/kota, hanya 5 daerah yang pendapatan per kapitanya lebih tinggi dari per kapita nasional. Berbasis indikator IPM didapati 14 Kabupaten memerlukan kebijakan afirmasi, dan 10 Kabupaten dengan indikator kemiskinan di atas angka 13%. Hasil kajian menunjukkan bahwa pemerintah Provinsi Jawa Timur memiliki peluang implementasi kebijakan afirmasi pendidikan dalam tiga bentuk: Pertama melalui jalur kebijakan transfer anggaran pada pos belanja Bantuan Keuangan kepada Kabupaten/kota, kedua melalui jalur Bantuan Hibah yang langsung ditransfer ke rekening sekolah, dan ketiga melalui regulasi yang menjamin mutu sekolah di daerah terpencil.Disparity in the quality of human resources among regions is a common symptom of regional development, included East Java. In addition to strenghening synergy between the government, civil society and the private sector, it is necessary to implement affirmative policies. The purpose of this study is to formulate educational affirmative policy in the context of eliminating disparity of human resource quality, according to resource capacity and the level of authority of the Government of East Java Province. Based on documents analysis method, shows that East Java's economic growth performance in 2019 is high, 5.52%, but it is still followed by a high poverty rate of 10.37%. The means years of school (MYS) of population is still 8.21 years, or equivalent of second grade of junior high school. From 38 regencies, only 5 regions have per capita income higher than the national per capita. Based on HDI indicators found 14 districts need affirmative policy, and using poverty indicators above 13%, there are 10 districts which need affirmative policy. The results of the study show that government of East Java has prospect to implement the affirmative policy in three forms: First through the Financial Aid expenditure (Bantuan Keuangan) transferred to the district/city account, second through the Grant Aid (Bantuan Hibah) which is directly transferred to school accounts, and the third through regulation of quality assurance for schools in remote area.
Aplikasi Soft System Methodology (SSM) Untuk Pengembangan Strategi Pemberantasan dalam Pandemi Covid-19 di Selandia Baru
Authors: Nuryanto Adi
Published: November 2021

Pemerintah Selandia Baru telah mengakhiri lockdown saat berhasil menekan angka kasus positif Covid-19 hingga nol selama 17 hari berturut-turut. Tingkat sistem peringatan telah diturunkan dari tingkat 4 menjadi tingkat 1 dalam waktu tujuh pekan. Pembatasan aktivitas sosial telah dilonggarkan dengan tetap memperhatikan protokol kesehatan seperti mencuci tangan, tidak menyentuh wajah, menutup batuk dengan lengan dalam dan menjalankan test kesehatan dan penelusuran kontak. Kebijakan dan strategi penangangan Covid-19 di Selandia Baru terdiri dari pengawasan (mitigation), penekanan (suppression) dan pemberantasan (elimination). Strategi pengawasan berupaya mengendalikan angka kasus positif sehingga kurva jumlah kasus positif melandai. Strategi penanggulangan dimaksudkan untuk menekan jumlah kasus seminimal mungkin. Sedangkan strategi pemberantasan ditujukan untuk membasmi virus Covid-19. Pengembangan strategi pemberantasan dalam pandemi Covid-19 memerlukan penentuan definisi yang kuat secara ilmiah mengenai pemberantasan Covid-19. Tujuan dari makalah ini adalah untuk dapat memberikan gambaran permasalahan dalam pengembangan strategi pemberantasan dalam pandemi Covid-19 di Selandia Baru menggunakan metode soft system methodology.
Pemberdayaan Dikalangan Calon Pekerja Migran Dalam Rangka Pencegahan Penyakit Menular di Desa Benculuk, Kecamatan Celuring, Kabupaten Banyuwangi Jawa Timur
Authors: Koesbardiati Toetik , Kinasih Sri Endah , Murti Delta Bayu , Ida Rachmah , Wahyudi Irfan
Published: November 2021

Rendahnya Pekerja Migran Indonesia (PMI) sebenarnya berkorelasi lurus dengan rendahnya tingkat pendidikan formal mereka. Rata-rata pendidikan formal sebanyak 68%  lulusan SD dan SMP. Pengetahuan PMI terkait dengan penularan penyakit yang disebabkan adanya pola-pola interaksi sangatlah rendah. Penyakit menular pada PMI terkait dengan pola-pola interkasi banyak dilakukan di negara tujuan. Hal ini tentunya  berdampak pada penyebaran penyakit menular pada PMI purna penempatan yang semakin meningkat bahkan menyebarluas bukan hanya di daerah pengiriman saja tetapi ke wilayah-wilayah yang bukan pengiriman PMI.WHO dari Komisi Migrasi dan Kesehatan menyampaikan adanya kerentanan para migran terkait dengan hak, perawatan kesehatan sebagai hak asasi manusia. Komisi ini memberikan rekomendasi menuju Global Health dengan misi migrasi sehat. Untuk merespon situasi ini maka studi ini membahas tentang pemberdayaan dikalangan  calon pekerja migran dalam rangka pencegahan penyakit menular  desa Benculuk, kecamatan Celuring, kabupaten Banyuwangi Jawa Timur ini diharapkan memberikan kontribusi untuk calon PMI terkait dengan pola-pola interaksi dan berperilaku sesuai standard kesehatan  dengan sesama migran, majikan maupun warga negara tujuan. Apabila ketika dalam pola-pola interaksi dan berperilaku tidak sesuai standard kesehatan maka akan berdampak penularan penyakit.  Pemberdayaan ini dilakukan di Serikat Buruh Migran Indonesia (SBMI) Desa Benculuk Kecamatan Cluring Banyuwangi  Provinsi Jawa Timur. Penentuan lokasi penelitian  ditentukan secara purposive di kabupaten Banyuwangi merupakan salah satu kabupaten dari tujuh kabupaten di Jawa Timur pengirim pekerja migran ke luar negeri. Pengumpulan data meliputi  observation  dan indepth interview. Informan yang dipilih adalah individu-individu yang memiliki pengetahuan dan pengalaman tentang permasalahan yang diteliti. Terakhir adalah analisa data  yaitu data yang terkumpul kemudian diklasifikasikan dan diindentifikasikan berdasarkan tema kemudian dianalisa.Hasil studi ini menunjukkan bahwa calon PMI belum memiliki pengetahuan tentang penyakit menular yang disebabkan oleh interaksi yang tidak tepat. Interkasi yang tepat akan mencegah terjadinya penularan penyakit. Apalagi informasi penularan penyakit tidak disampaikan pada pelaksanaan Pembekalan Akhir Pemberangkatan (PAP) dan tidak didukung dengan menggunakan media pengajaran seperti video, simulasi dan hanya menggunakan metode ceramah. Demikian materi yang disampaikan tidak sesuai dengan modul pegangan instruktur. Dengan adanya pemberdayaan dikalangan calon PMI terkait dengan bahaya penyakit menular perlu adanya kiat-kiat untuk menghindarinya dengan membatasi interaksi di negara tujuan.
Health Risk Due to Carbamate Exposure in Communities Around Paddy Field Areas
Authors: Maksuk Maksuk - , Shobur Sherli - , Suzanna Suzanna -
Published: November 2021

Introduction: Carbamate is one of the most widely used pesticides in paddy field areas, which causes environmental pollution and human health problems. Therefore, this study aims to analyze the health risks of carbamate exposure in communities around paddy fields areas. Methods: This was an observational analysis study conducted using the health risk assessment approach. There were 20 samples of waterway streams from 10 sites observed in the morning (at high tide) and evening (at low tide) taken using a grab sampling method. The parameters of the waterway streams river, such as pH and temperature, were measured on-site using a pH meter and portable thermometer, while the carbamate concentration was analysed in the laboratory using High-Performance Liquid Chromatography (HPLC). Results and Discussion: The active ingredients of carbamate pesticides that observed as follows: aldicarb (0 – 0.05 mg/l), carbaryl (0 – 0.01 mg/l), carbofuran (0-0.005 mg/l), and propoxur (0-0.001 mg/l). While the pH (6.4 – 7.5) and temperature (22.1 – 32.4oC). The potential exposure of Aldicarb in grown-up and kids were 0.042 and 0.077 mg/kg bodyweight-day, respectively. Furthermore, the potential exposure of carbofuran in Grown-ups and kids were 0.004 and 0.01 mg/kg bodyweight-day, respectively. Only the carbofuran exposure in kids has a rate of RQ > 1, which is unsafe or can cause non-carcinogenic effects in the next 30 years. Conclusion: Although the carbamate concentrations in waterway streams around paddy field areas were below the quality standard, it is not safe. Therefore, it is necessary to carry out risk management and communication with local policymakers.
Human Leptospirosis Outbreak: A Year After the ‘Cempaka’ Tropical Cyclone
Authors: Syakbanah Nur Lathifah , Fuad Anis
Published: November 2021

Introduction: The ‘Cempaka’ Tropical Cyclone hit south Java in November 2017, causing heavy rainfall and severe flooding. Changes in climate variability and extreme weather events may shift the geographic and seasonal patterns of neglected tropical diseases such as leptospirosis. This study analyses the Spatiotemporal pattern between flooding, weather, and human leptospirosis cases after a tropical cyclone. Methods: This was an ecological study that collected monthly flooding data, weather data, and human leptospirosis data cases per village from November 2017 to October 2018, a year after the ‘Cempaka’ Tropical Cyclone in Bantul. Spatio-temporal analyses were calculated to 0-3 months lag by Pearson's correlation, spatial mapping, and time-series graphs. Results and Discussion: As many as 99 people infected with leptospirosis were found in all 75 villages in Bantul. The villages affected by flooding were 44% and leptospirosis cases spread in 68% of villages. A 1-month lag (r = 0.6849; p < 0.05) and 3-months lag (r = 0.6666; p < 0.05) of relative humidity along with a 1-month lag (r = 0.7451; p < 0.05) and 3-months lag (r = 0.8561; p < 0.05) of rainfall were found to be correlated to human leptospirosis cases. Heavy rain due to the Cempaka Tropical Cyclone caused flooding and transmission of Leptospira bacteria into the water and heightened contact between humans, animals, and the environment. Conclusion: It is found that flooding, relative humidity, and rainfall after the Cempaka Tropical Cyclone would be followed by human leptospirosis outbreaks 1 and 3 months later. Cross-sectoral cooperation of public health authorities should integrate climatic information as an early warning for disaster-prone areas and community groups at risk.
Penerimaan Pengguna Instagram terhadap Analogi Visual Seksualitas dengan Makanan oleh Influencer Instagram
Authors: Rigita Rizki Fauzia Intan
Published: November 2021

This research focuses on the acceptance of Instagram users to the visual analogy of sexualitywith food by Instagram influencers when delivering sex education material that is stillconsidered taboo in Indonesia. By using a qualitative approach and a type of descriptiveresearch, this research focuses on the meaning received by the nine informants who haveparticipated. The research method used is Reception Analysis with in-depth interviews as datacollection technique. The literature review used is a visual analogy to explain the taboo aboutsexuality, sexuality in Indonesia, problems of formal sex education, symbolic construction ofsexuality in traditional media, and sexuality content that appears on Instagram social media.The findings of this study indicate that the informants interpret the visual analogy of sexualitybased on the concept of heteronormativity in everyday life. Then, stereotypes about sexualitythat develop in the community also become a reference when they answer questions. Theperception of the state of Indonesia as homophobic and transphobic country, but when facedwith a visual analogy in the form of food, the informants did not object to the existence ofLGBT groups or to the concept of homosexuality
Virtualización Integral de Asignaturas de Expresión Gráfica en los Grados de Ingeniería = Comprehensive Virtualization of Graphic Expression Subjects in Engineering Degrees
Authors: Carrasco-Amador Juan Pablo , García-Sanz-Calcedo Justo , Moral Francisco J. , González-Domínguez Jaime , Matamoros-Pacheco Manuel , Sánchez-Barroso Gonzalo
Published: November 2021

El principal objetivo de este trabajo ha sido la virtualización de diferentes asignaturas del departamento de Expresión Gráfica de la Escuela de Ingenierías Industriales, entre las que se encuentran: Instalaciones Industriales y Comerciales II, Aplicaciones Informáticas para la Ingeniería e Ingeniería Gráfica. Las dos primeras se imparten en todos los Grados de Ingeniería de la Rama Industrial y la tercera, en el Grado de Ingeniería Mecánica y como asignatura optativa en el Grado de Ingeniería Electrónica y Automática. Para ello se han utilizado herramientas como OBS Studio, Zoom, Socrative o Moodle, empleadas para la elaboración de video tutoriales con resolución de problemas, cuestionarios, rúbricas y pruebas de evaluación, etc. La aplicación de las metodologías docentes descritas, así como la virtualización de los contenidos, han contribuido a mejorar y facilitar el aprendizaje por parte de los estudiantes, y han recibido una muy buena valoración y aceptación por parte de los alumnos.AbstractThe main objective of this project has been the virtualization of different subjects of the Department of Graphic Expression of the School of Industrial Engineering, among which are: Industrial and Commercial Installations II, Computer Applications for Engineering and Graphic Engineering. The first two are taught in all Engineering Degrees of the Industrial Branch and the third, in the Mechanical Engineering Degree and as an optional subject in the Electronic and Automatic Engineering Degree. For this, tools such as OBS Studio, Zoom, Socrative or Moodle have been used for the development of video tutorials with problem solving, questionnaires, rubrics and evaluation tests, etc. The application of the teaching methodologies described, as well as the virtualization of the contents, have contributed to improve and facilitate learning by students, and have received a very good evaluation and acceptance by students
Energy Savings and Efficiency at Secondary School Buildings. (ElhZA+ENEDI PROYECT)
Authors: Picallo-Pérez A. , Sala-Lizarraga J. M. , Escudero-Revilla C. , Lasa-Iglesias A. , Solabarria D. , Hidalgo J. M. , Romero N. , Odriozola M. , Gómez-Arriaran I.
Published: November 2021

AbstractThis work describes the project submitted to the University-Society-Business 2021 call for proposals whose aim is to integrate the knowledge and university practices in the field of energy in buildings into secondary school students. The aim is to define the energy strategies to be implemented to strengthen the relationship between secondary education and university studies, by means of a "pilot project" at a secondary school, as well as to promote Science, Technology, Engineering and Maths (STEM) scientific vocations in young people, with particular emphasis on the female gender. The project will carry out an energetic study at a school developed by university research staff and secondary school students. The aim is to motivate and confirm the qualities of people in STEM teaching, to arouse interest and closeness as well as to promote education in the subject of energy efficiency in buildings
Impact of Ocean Currents on Wind Stress in the Tropical Indian Ocean
Authors: Chacko Neethu , Ali M M
Published: November 2021

This study examines the effect of surface currents on the bulk algorithm calculation of wind stress estimated using the scatterometer data during 2007-2020 in the Indian Ocean. In the study region as a whole the wind stress decreased by 5.4% by including currents into the wind stress equation. The most significant reduction in the wind stress is found along the most energetic regions with strong currents such as Somali Current, Equatorial Jets and Aghulhas retroflection. A highest reduction of 11.5% is observed along the equator where the Equatorial Jets prevail. A sensitivity analysis has been carried out for the study region and for different seasons to assess the relative impact of winds and currents in the estimation of wind stress by changing the winds while keeping the currents constants and vice versa. The inclusion of currents decreased the wind stress and this decrease is prominent when the currents are stronger. This study showed that equatorial Indian Ocean is the most sensitive region where the current can impact on wind stress estimation. The results showed that uncertainties in the wind stress estimations are quite large at regional levels and hence better representation of wind stress incorporating ocean currents should be considered in the ocean/climatic models for accurate air-sea interaction studies.
N1-Methyladenosine (m1A) Regulator-Mediated Methylation Modification Modes and Tumor Microenvironment Infiltration Characteristics in Head and Neck Squamous Cell Carcinomas
Authors: Miao Yan-Dong , Mu Lin-Jie , Tang Xiao-Long , Wang Jiang-Tao , Wu Jing-Jing , Chen Yong-Gang , Mi Deng-Hai
Published: November 2021

Background: Recent researches have investigated the biological importance of RNA N1-methyladenosine (m1A) modifications in oncogenesis and progression of head and neck squamous cell carcinoma (HNSCC). However, whether m1A modifications also have latent effect in tumor microenvironment (TME) generation and immune regulation in HNSCC is unknown. Methods: We evaluated the m1A modification patterns and related to these modification patterns with TME cell infiltration features in 1041 HNSCC samples by bioinformatics approach. Results: The m1A score is an independent prognostic indicator. HNSCC patients with low m1A score group with poor overall survival (OS) was mainly characterized by stroma activation, lack of sufficient immune infiltration, and exhibited an immune- desert TME phenotype. Low m1A scores were also correlated with increased tumor mutation burden (TMB), and HNSCC patients with high TMB and low m1A scores had the worst OS. In addition, anti-CTLA-4 combined with anti-PD1 treatment was more effective in the high m1A score subgroup than in the low m1A score subgroup. Conclusions: This study revealed that m1A modifications play a non-negligible role in developing the TME versatility and complexity of HNSCC. Assessing m1A modification patterns in HNSCC helps improve our comprehension of its TME infiltration profile and guides more effective immunotherapeutic approaches.
Prevention of hazards induced by a Radiation Fireball through Computational Geometry and Parametric Design
Authors: Salguero-Andújar Francisco , Cabeza-Lainez Joseph M. , Blasco-Macias Federico
Published: November 2021

Radiation Fireballs are singular phenomena which involve severe thermal radiation and consequently, they need to be duly assessed and prevented. Although the radiative heat transfer produced by a sphere is relatively well known, the shadowing measures implemented to control the fireball’s devastating effects have frequently posed a difficult analytical instance, mainly due to its specific configuration. In this article, since the usual solving equations for the said cases are impractical, the authors propose a novel graphic-algorithm method that sorts the problem efficiently for different kinds of obstructions and relative positions of the fireball and the defenses. Adequate application of this method may improve the safety of a significant number of facilities exposed to such risks.
Propagation of a Gaussian-Top-Hat Function
Authors: Anaya-Contreras Jorge , Zúñiga-Segundo Arturo , Sánchez-de-la-Llave David , Moya-Cessa Hector
Published: November 2021

We study the propagation of a particular field that we call Gaussian-top-hat that presents self-focusing and maintains its shape for some propagation distances.
Deficiency of MMP-10 Aggravates the Diseased Phenotype of Aged Dystrophic Mice
Authors: Baraibar Churio Arantxa , Bobadilla Miriam , Sainz Neira , Machado Florencio JD , Orbe Josune , Pérez-Ruiz and Ana
Published: November 2021

Matrix metalloproteinases have been implicated in muscular dystrophy progression and recent studies described the role of MMP-10 in skeletal muscle pathology of young dystrophic mice. Nevertheless, its implication in dystrophin deficient hearts is still missing. Here, we aimed at investigating MMP-10 implication in severe muscular dystrophic progression and characterize MMP-10 loss in skeletal and cardiac muscles of aged dystrophic mice. We examined the histopathological effect of MMP-10 ablation in aged mdx mice, both in the hind limb muscles and heart tissues. We have found that MMP-10 loss compromises survival rates of aged mdx mice, with skeletal and cardiac muscles developing a chronic inflammatory response. Our findings indicate that MMP-10 is implicated in severe muscular dystrophy progression, identifying a new area of investigation that could lead to future therapies for dystrophic muscles.
The Immunomodulatory Activity in vitro of NDV ZG1999HDS in Comparison to NDV La Sota
Authors: Filipič Bratko , Gradišnik Lidija , Pereyra Adriana , Mazija Hrvoje
Published: November 2021

ABSTRACT. The immunotherapies, as a modern therapeutic approach, get an attention because of theirs’ promise to treat a large number of different medical disorders. Immunomodulation effects of low titres (10 HA/ml) of NDV (Newcastle Disease Virus) ZG1999HDS or La Sota were tested on TLT (Human macrophage cell line) bound to PBMC (Peripheral Blood Mononuclear Cells). During the immunomodulation, the amount of NO, H2O2, lysozym and induced antibacterial activity against Gram - positive bacteria (Staphylococcus aureus, MRSA, Streptococcus pyogenes, Streptococcus agalactiae and Streptococcus mutants) and against Gram - negative bacteria (Escherichia coli, Pseudomonas aeruginosa, Proteus mirabilis and Acinetobacter baumanii) were analysed. In addition, the cytokine secretion, IL-1α, IL-2, IL-4, GM-CSF, TNF-α, IFN-α and IFN-α were evaluated. Firstly, the TLT cells are activated through the NDV ZG1999HDS or La Sota binding, followed by the NO “burst” and H2O2 and lysozyme level increase. Secondly, after the binding to the TLT cells and interaction with the PBMCs, the decrease of GM-CSF, and an increase of TNF – α and IFN – γ were found. Simultaneously, the decrease of pro – inflammatory cytokine IFN-α and the differentially increase of IL-1α, IL-2 and IL-4 were recorded. During the induction of the antibacterial response, against Gram - positive bacteria (Staphylococcus aureus, MRSA, Streptococcus pyogenes, Streptococcus agalactiae and Streptococcus mutants) the effect was one third higher with NDV ZG1999HDS compared to La Sota. Antibacterial response against Gram - negative bacteria (Escherichia coli, Pseudomonas aeruginosa, Proteus mirabilis and Acinetobacter baumanii) was not so clear. In general, NDV ZG1999HDS or La Sota activated TLT cells, further bound to PBMC; the ZG1999HDS is stronger immunomodulator than La Sota.
A Systematic Literature Review of Blockchain-Based Crops Traceability in Agricultural Supply Chain
Authors: Sakib S M Nazmuz
Published: November 2021

In recent years, Blockchain has been favorably adopted in the Supply Chain industry as it provides guaranteed transparency and traceability. The flexibility of Blockchain allows different applications to enable to exchange information; a significant middleweight layer is responsible for information transfer in the Agricultural Sector. The products that are manufactured at a global level in the agriculture industry are improved in safety, validation of some criteria, and quality. In the agriculture industry, the increasing number of complications associated with food safety and impurity risks needs high-level effective traceability solutions that act as necessary quality management tools to make sure satisfactory safety of crops. The agricultural supply chain today has complex ecosystems, consisting of several stockholders to authenticate criteria which are important like crop development stages, monitoring and validation, and compliance with the quality standard. In this proposed research, a systematic literature review will be done that includes smart contracts, Blockchain, and business transactions exclusively for crop production traceability across the agricultural and food supply chain. By using Blockchain in the agriculture sector, productivity, consistency, safety, reliability, and advanced security are increased. All transactions are kept and recorded on the immutable record of Blockchain associates with a decentralized system. Thus, it provides more traceability and clarity in the agriculture system in asafe, trustworthy, and effective way. A systematic literature review is thus enforced to classify the papers which are selected by the following classification: crop traceability, contribution type, research type, and their approach. For this systematic review, the papers which extracted are classified according to defined criteria. The purpose of this study is to fill the gap by collecting and analyzing studies available within the literature aiming to firstly, gain complete insight on the integration of Blockchain in the agriculture sector. Secondly, provide a summary of the present state of research on this area and identify gaps in existing studies. To achieve this aim an SLR was conducted. The findings of this SLR are discussed and researchers were provided with suggestions on possible directions for future research.
Association of Maternal Observation and Motivation (MOM) Program with M-Health Support on Maternal and Newborn Health
Authors: Paulsamy Premalatha , Easwaran Vigneshwaran , Ashraf Rizwan , Venkatesan Krishnaraju , Moustafa Mervat , Qureshi Absar Ahmed , Prabahar Kousalya , Periannan Kalaiselvi , Vasudevan Rajalakshimi , Kandasamy Geetha , Chidambaram Kumarappan , Pappiya Ester Mary , Venkatesan Kumar , Manoharan Vani
Published: November 2021

Maternal and child nutrition has been a critical component of health, sustainable development, and progress in low- and middle-income countries (LMIC). While a decrement in maternal mortality is an important indicator, simply surviving pregnancy and childbirth does not imply better maternal health. One of the fundamental obligations of nations under international human rights law is to enable mothers and teenage girls to endure pregnancy and delivery as an aspect of their enjoyment of reproductive and sexual health and rights and live a dignified life. The aim of this study was to discover the correlation between the Maternal Observation and Motivation (MOM) program and m-Health support for maternal and newborn health. A Comparative study was done among 109 pregnant mothers (study group-94; control group-102 mothers) with not less than 20 weeks of gestation. Maternal outcomes such as Hb, weight gain and newborn results like birth weight and crown- heel length was obtained on the baseline, 28 and 36 weeks of gestation. Other secondary data collected were abortion, stillbirth, low birth weight, major congenital malformations, twin or triplet pregnancies, physical activity and maternal wellbeing. The MOM intervention included initial face to face education, three in-person visits and eight virtual health coaching by WhatsApp. The baseline data on Hb of the mothers show that 31(32.98%) vs 27(28.72%) of the study and control group had anaemia, which improved to 27.66% and 14.98% among study group mothers at 28 and 36 weeks of gestation (p<0.001). The weight gain (p< 0.001), level of physical activity (p< 0.001), and maternal wellbeing (p< 0.01) also had significant differences after the Intervention. Even after controlling for potentially confounding variables, the maternal food practices regression model revealed that birth weight was directly correlated with consumption of milk (p 0.001), fruits (p 0.01), and green vegetables (p 0.05).As per the physical activity and maternal wellbeing regression model, the birth weight and crown heel length were strongly related with the physical activity and maternal wellbeing of mothers at 36 weeks of gestation (p <0.05). Combining the MOM intervention with standard antenatal care is a safe and effective way to improve maternal welfare while upholding pregnant mothers' human rights.
Cell Biology, Genetics, and Biochemistry for Pre-Clinical Students
Authors:   Virginia Tech Carilion School of Medicine, LeClair Reneé
Published: November 2021

This book is an undergraduate medical-level resource for foundational knowledge across the disciplines of genetics, cell biology and biochemistry. This text is designed for a course in first year undergraduate medical course that is delivered typically before students start to explore systems physiology and pathophysiology. The text is meant to provide the essential information from these content areas in a concise format that would allow learner preparation to engage in an active classroom. Clinical correlates and additional application of content is intended to be provided in the classroom experience. The text assumes that the students will have completed medical school prerequisites (including the MCAT) in which they will have been introduced to the most fundamental concepts of biology and chemistry that are essential to understand the content presented here. This resource should be assistive to the learner later in medical school and for exam preparation given the material is presented in a succinct manner, with a focus on high-yield concepts.
Using Song Dialects to Assess the Migration Strategy of the Golden-crowned Sparrow
Authors: Pandolfino Edward R. , Douglas Lily A.
Published: November 2021

Most techniques used to study migration of wild birds require capture for banding or for attachment and/or recovery of tags or transmitters. We took advantage of the fact that the Golden-crowned Sparrow (Zonotrichia atricapilla) sings in winter, combined with published data on the distribution of its distinct song dialects in the breeding range, to assess its migration strategy and migratory connectivity by means of these dialects. Using recordings of the Golden-crowned Sparrow’s song across much of its winter range, we categorized these birds by song type to identify their likely origin in some subset of the breeding range. This method allows examination of migration without the need to capture birds. Our results fit best with a pattern of chain migration, with the northernmost breeders wintering in the northernmost part of the winter range, and the southerly breeders wintering farther south. The results suggest strong migratory connectivity between segments of the breeding and winter ranges, though our small sample size makes it difficult to draw firm conclusions on connectivity.
A Multi-Mode Reasoning For Predicting Tobacco Baking Quality
Authors: Wu QingE , Zong Tao , Chen Hu , Zhou Lintao , Lu Yingbo , Li Penglei , Li Yong
Published: November 2021

In order to reduce the number of defective products caused by the unreasonable baking time during the tobacco production process, this paper proposes a method for establishing a multi-model reasoning tobacco baking quality prediction model. Conduct data mining and analysis on the data of various indicators of the original tobacco, and screen out the data that have an impact on the quality of tobacco baking. In order to reduce the complexity of the model and eliminate the influence between different dimensions, the data are carried out and standardized processing. Next, the normalized data is explored for the multi-input and multi-output mapping relationship. Finally, a mapping matrix is given for the multi-input and multi-output mapping relationship so as to establish a tobacco baking quality prediction model. The test results show that the predicted value of this model is basically the actual value, and the prediction accuracy rate is more than 90%. It has a high prediction accuracy rate. The cured tobacco leaves are basically the same as the actual cured yellow expected value. This model provides a practical guide method for tobacco baking, which has certain practical value in actual tobacco baking.