bluuebunny/crossref_metadata_2025 huggingface dataset:
The Ceramic Sherd Assemblage from the C. D. Marsh Site (41HS269) in Harrison County, Texas
Authors: Perttula Timothy K. , Walters Mark , Haskins Patti
Published: May 2019

The C. D. Marsh site (41HS269) is an ancestral Caddo settlement and cemetery on Eight Mile Creek, a southwestward–flowing tributary to the Sabine River in southeastern Harrison County, Texas. It is on an alluvial terrace about 1.6 km from the confluence of Eight Mile Creek and the Sabine River.

Buddy Calvin Jones discovered the site in January 1958, and he estimated that the habitation area covered ca. 1–2 acres, with substantial midden deposits. Jones collected a substantial sample of plain and decorated ceramic vessel sherds (n=1736) from the habitation deposits (Jones 1968:96), in addition to a number of ceramic vessels and other funerary offerings from Caddo burial features. A subset of this reported sherd assemblage has been identified in the collections of the Gregg County Historical Museum, and the 2015 analysis of that sherd sample is the subject of this article.
Caddo Ceramic Assemblage from a Site Across the Road from the Millsey Williamson Site in Rusk County, Texas
Authors: Perttula Timothy K.
Published: May 2019

In archaeological investigations by Jones at the Nadaco Caddo Millsey Williamson site (41RK3), he identified a burial area on the western tip of an alluvial terrace landform on the east side of Martin Creek, as well as a village area to the east. The burial area and the village area were separated by a road, a paved segment of the 19th century Trammel’s Trace. Trammel’s Trace was an Anglo–American version of the aboriginal Caddo Trace “that led from the Hasinai Caddo settlements in East Texas to the Kadohadacho settlements on the Red River in the general area of Texarkana, Texas, and its route is fairly well known because the historic 19th–century Trammel’s Trace followed its route through northeastern Texas." The collection of ceramic sherds discussed in this article are from the village, namely the site area across [and to the east] from the Millsey Williamson historic Caddo cemetery; they are in the collections of the Gregg County Historical Museum. A number of the sherds were collected from this area before 1945 by a Mr. C. W. Bailey, who donated them to Buddy Jones for study.
A Ceramic Sherd Assemblage from a Caddo Site in the Upper Neches River Basin, Henderson County, Texas
Authors: Perttula Timothy K.
Published: May 2019

This article reports on a collection of ancestral Caddo artifacts from an unrecorded site in the upper Neches River basin in northeastern Henderson County in East Texas. The collection had been found by landowners on an unreported Caddo site in this locale—which appears to be in the Caddo Creek valley west of the Neches River—and the collection was recently relocated by Debbie Shelley of Frankston, Texas. Mrs. Shelley brought the collection to the 2015 East Texas Archeological Conference, and provided the opportunity to fully document the ceramic and lithic artifacts in the collection.
The Frank Norris Farm Site (41RR2) on the Red River in East Texas
Authors: Perttula Timothy K. , Walters Mark
Published: May 2019

The Frank Norris Farm site (41RR2) was an ancestral Caddo settlement and mound center, with an associated cemetery, on the bank of the Red River, about five miles northeast of the community of Manchester, Texas, and just southeast of the Sam Kaufman/Roitsch site (41RR16). The site was reported by B. B. Gardner of the University of Texas to have three earthen mounds. Apparently the site eroded into the Red River in 1936.

The three mounds at the site were located east of a local farm road, and the bank of the Red River was a short distance to the east. Mound No. 1 was ca. 27 m in length, 23 m in width, and 3 m in height; Mound No. 2 was ca. 33.5 m in length, 24 m in width, and 3.7 m in height; and Mound No. 3 was ca. 18 m in length, 12 m in width, and 1.8 m in height. Gardner trenched Mound No. 1 in the summer of 1930 but found only a few sherds and no obvious features. A low alluvial ridge not far south of Mound No. 3 was also trenched by Gardner, and he recovered sherds from archaeological deposits there.

Gardner also noted that in the Red River cut bank was an ca. 46-61 cm thick archaeological deposit with black sediments and ceramic sherds. Although Gardner’s 1930 notes are not specific, he apparently excavated at least one burial at the Frank Norris Farm. Correspondence in the Texas Archeological Research Laboratory (TARL) files stated that Gardner found burials that were from 1.2-1.5 m in depth and scattered across the site.

Local diggers began to search out and excavate Caddo burials at the Frank Norris Farm site in 1934 and 1935, and these diggers sold the ceramic vessels and other funerary offerings (including a spatulate celt, arrow points, and shell beads) they found to local collectors like George T. Wright. According to W. A. Rikard, an interested avocational archaeologist from the region, at least nine burials had been found and dug by collectors at the site, not including the one or more burials he excavated there. He did mention in 1935 correspondence to A. T. Jackson that one burial he excavated was in a 1.2 m deep pit and had a shell-tempered neck banded jar as an associated funerary offering. He also noted that other Caddo burials were being exposed in the eroding cut bank of the Red River, where they were easily looted.
Update on Recent Activities at the Arkansas Archeological Survey’s Henderson State University Research Station in Arkadelphia
Authors: Trubitt Mary Beth D.
Published: May 2019

The Arkansas Archeological Survey’s Henderson State University Research Station (ARAS/HSU) has been active with several small field projects this year, as well as on-going work in the lab. In February and March 2016, Mary Beth Trubitt and Katie Leslie advised Hot Springs National Park personnel on placement of four soil moisture monitors so as to avoid cultural features at 3GA22, a significant novaculite quarry with prehistoric and historic components. In the process, we were able to map additional quarry features, most of which are associated with early twentieth century whetstone procurement. Our fieldwork and documentation resulted in extending the site boundaries. Eight shovel tests were excavated during the park’s installation of soil monitoring equipment. This represents the first subsurface archeological testing at this quarry. The novaculite debris from shovel tests included quarry waste and natural talus, but few flakes and no tools or diagnostic artifacts were found. After analysis of lithic debris, a report was prepared that outlines past research on the site and its significance, and summarizes the results of the project.
Salvage along the Red River: The Red Cox (3LA18) Site and its Place on the Caddo Landscape
Authors: McKinnon Duncan P. , Nguyen Ryan , Yeager Tyler , Bush Leslie L.
Published: May 2019

The Red Cox (3LA18) site is located in Lafayette County, Arkansas along the Red River. As recounted in his weekly report of April 9, 1975, Dr. Frank Schambach received word that the site was being directly impacted by land leveling machinery. Salvage efforts collected the remains from the floor of a burned Caddo farmstead structure. Remains include ceramic sherds, carbonized corn kernels, acorn nutmeat and nutshells, burned wood fragments, and bits of daub. In this paper, we present the results of a recent analysis of the materials and situate the farmstead within the Red River landscape during a period shortly after Haley (ca. A.D. 1200 - 1400) phase and into the early part of the Belcher (ca. A.D. 1400 - 1700) phase.
The Adair Site: Caddo Relations through Ceramic Analysis
Authors: Starr Joanne D.
Published: May 2019

The Adair site (3GA1), located in the Upper Ouachita River Valley in Garland County, Arkansas is an Upper Ouachita Caddo site. The people at the site are presume to be at the center of cultural dominance for the area and had interaction with Caddo sites in the region. This article explores this by studying the whole vessel collections that were excavated at the Adair site in the 1930s. Comparing the Adair collection to three other Caddo sites provides information about the social standing of the Adair site, its relations with other sites, and how it fits into the greater fabric of Caddo culture in the Upper Ouachita River Valley.
An Ancestral Caddo Ceramic Vessel from the Molly Cameron Site (41BW18) in the Sulphur River Basin in East Texas
Authors: Perttula Timothy K.
Published: May 2019

The Molly Cameron site is an ancestral Caddo habitation site with burial features in the Sulphur River basin in East Texas, specifically on Aiken Creek, a southward-flowing tributary, about one mile east of the dam at Lake Wright Patman. The site was first exposed in 1928, when plowing of the land owned by W. K. Cameron exposed several ceramic vessels and human remains. One of the vessels was purchased by The University of Texas at Austin in August 1932; that vessel is documented below.
The Effects of Horses and Raiding on the Salt Industry in Northwest Louisiana
Authors: Eubanks Paul N.
Published: May 2019

When French explorers first arrived in northwest Louisiana, the local Caddo Indians had already earned a reputation for being important players in the salt trade. Likewise, many western Caddo groups living near the southern Plains were known for their involvement in the horse trade. In the first part of this paper, the relationship between the local salt industry and the introduction of the horse is considered. It is suggested that at least some of the salt made in northwest Louisiana was being fed to horses and other livestock acquired either directly or indirectly from the Spanish. In addition to its potential effect on the salt trade, the introduction of the horse in the southern Plains also spurred an increase in theft and raiding. Historical data suggest that Caddo salt producers may have been worried about such activities from hostile groups like the Osage and Chickasaw. In the second part of this paper, it is argued that these Caddos may have tried to discourage raiding by using salt licks bordered by waterways, by working in close proximity to other salt producers, and by traveling long distances to reach well-protected salt production sites.
Current Research: Toward a Collaborative Development of a Truly Comprehensive Multi-State Material Culture Database
Authors: McKinnon Duncan P.
Published: May 2019

Throughout the past several years, I have been compiling, with the help of several Caddo researchers, a comprehensive multi-state database primarily composed of whole Caddo vessels from published excavations, private collections, and archaeological reports. At present, the database contains over 13,000 vessel entries from over 500 sites ranging from a single vessel recorded at a site to hundreds. Over the years, the database has evolved to contain, where applicable, attribute fields on type, variety, motif designs (largely using the Glossary of Motifs published in the Spiro shell engravings, collegiate assignment, form, temper, decorative method (incised, brushed, etc.), context (burial #, site #, intra site location), pigment, archaeological phase, collector, repository, associated photographs, and reference citations. The database is managed using Microsoft Access where data are imported into ESRI ArcGIS and spatial analyses can be conducted.

This is a continual, and perhaps never-ending, work in progress where attribute fields are added, types are vetted, and new sites are included. In some cases, “Caddo-like” vessels from sites outside the Caddo Archaeological Area, or Caddo Homeland, are included in order to evaluate social interaction and exchange of ideas. Through this process, some initial insights into landscape scale social interactions and interregional relationships using this growing comprehensive database have been explored.
PERAN GREEN SUKUK DALAM MEMPERKOKOH POSISI INDONESIA DI PASAR KEUANGAN SYARIAH GLOBAL
Authors: Anggraini Yulia
Published: May 2019

Abstract: This research was motivated by the development of sukuk in Indonesia from an international perspective in 2016 which gave positive results. Where Indonesia is the big issuer of sukuk with a total issuance of USD 10, 5 billion from the total issuance of sukuk by the government from all over the world. In the midst of the development of sukuk instruments, there are also instruments such as green bonds that offer investments in environmental development. With the presence of green bonds as investment instruments in the environment, a sharia investment instrument has emerged which has the same concentration as a green bond. The instrument is then called green sukuk. Indonesia is listed as a pioneer in the issuance of green bonds in the Southeast Asia region. The purpose of this study is to identify the potential of sukuk green publishing in Indonesia to strengthen Indonesia's position in the global sharia financial market. This study uses a qualitative approach using historical methods. الملخص: يتم تحفيز هذا البحث من خلال نظرة إيجابية من المنظور الدولي حول تطوير الصكوك في إندونيسيا في عام 2016. حيث تعد إندونيسيا المصدر الكبير للصكوك بإجمالي ,510 دولارات أمريكية من إجمالي إصدارات الصكوك من قبل الحكومة من جميع أنحاء العالم. في خضم تطوير أدوات الصكوك، هناك أدوات مثل green bond  التي تقدم استثمارات في التنمية البيئية.بعد وجود هذه الأدوات كأداة استثمار في البيئة ، تظهر أداة استثمار الشريعة التي لها نفس تركيز له  يسمى الصكوك الخضراء green sukuk. ومن هنا تم إدراج إندونيسيا كرائد في إصدار السندات الخضراء في منطقة جنوب شرق آسيا. الغرض من هذه الدراسة هو تحديد إمكانات النشر الأخضر للصكوك في إندونيسيا لتعزيز مكانة إندونيسيا في السوق المالية الشرعية العالمية. تستخدم هذه الدراسة منهجًا كميًا باستخدام الطريقة التاريخية.. Abstrak: Penelitian ini dilatar belakangi oleh adanya perkembangan sukuk di Indonesia dari kacamata internasional pada tahun 2016 yang memberikan hasil positif. Dimana Indonesia merupakan the big issuer sukuk dengan total penerbitan USD 10, 5 Milyar dari total penerbitan sukuk oleh pemerintah dari seluruh dunia. Ditengah perkembangan instrumen sukuk telah hadir juga instrumen berupa green bond yang menawarkan investasi pada pembangunan lingkungan. Dengan hadirnya green bond sebagai instrumen investasi pada lingkungan telah muncul sebuah instrumen investasi syariah yang konsentrasinya sama dengan green bond. Instrumen tersebut kemudian disebut green sukuk. Indonesia tercatat sebagai pionir dalam penerbitan obligasi hijau di kawasan Asia Tenggara. Tujuan  dari penelitian ini adalah mengidentifikasi potensi penerbitan green sukuk di Indonesia memperkokoh posisi Indonesia di pasar keuangan syariah global. Penelitian ini menggunakan pendekatan kualitatif dengan menggunakan metode historis.
In vitro activity of methylene blue and EMB agar on colistin-resistant A.baumannii: An experimental study
Authors: Gazel Deniz , Otkun Müşerref Tatman , Akçalı Alper
Published: May 2019

Background

Colistin is one of the last resort antibiotics used against carbapenem-resistant Acinetobacter baumannii (AB); however, colistin resistance has been reported recently. Methylene blue (MB) is used in microbiology for staining, and in medicine as an antidote drug. Here, we investigated antimicrobial effects of MB and Eosin Methylene blue (EMB) agar against colistin-resistant AB strains.

Methods

The AB ATCC 19606 strain and 31 AB clinical isolates were included in the study. In the first round, ATCC strain and a clinical isolate were transformed into colistin-resistant forms, using Li's method, with increasing colistin concentrations. At each step, new MICs were determined and subcultures were inoculated to EMB and sheep blood agar (SBA). The colistin MIC values of the subcultures were also determined using Mueller Hinton Agar (MHA) containing 14 µg/mL MB. In the second round, colistin resistant clones of all collected clinical isolates (n=31) were obtained and screened to investigate their susceptibility to EMB agar by inoculating on SBA and EMB agar.

Results

At the beginning, the MICs of two strains were 0.5 µg/mL. At the last stage, both MICs had risen to 64 µg/mL. Subpopulations with high colistin resistance (>=32 µg/mL) were inhibited by MB and EMB agar, but could grow well on SBA. In MHA plates containing MB, the MICs decreased to the 0.5 µg/mL level for colistin-susceptible or moderately resistant clones. Additionally, clones with high colistin resistance showed atypical colony morphology on SBA. In the second round, MICs of the colistin resistant clones of all clinical isolates rose to 8 µg/mL after colistin exposure and 35% of those clinical isolates were inhibited by EMB agar while they could grow on SBA.

Conclusion

Highly resistant strains were totally inhibited by the effect of MB and EMB agar, while the MICs of the susceptible and moderate resistant clones decreased. EMB agar and MB may have inhibitory effects against colistin-resistant AB strains and MB may have a potential to be used as an antimicrobial drug. Secondly, using only EMB agar for subculturing may cause missing of colistin-resistant strains and giving incorrect identification or antibiogram reports in clinical microbiology laboratories.
Human freedom and border situations in the physical history of existentialism
Authors: Latypov Nizam Olegovich
Published: May 2019

This article discusses the concepts of "freedom" and "borderline situations", their interaction. The views of the leading existentialist philosophers regarding these concepts were also examined in detail.
Lei de Acesso ao Patrimônio Genético e seu impacto na pesquisa científica brasileira
Authors: CAGLIARI Alexandro
Published: May 2019

A Lei de Acesso ao Patrimônio Genético (Lei no 13.123, de 20 de maio de 2015) foi criada com o objetivo de regulamentar o acesso ao patrimônio genético de espécies vegetais, animais (exceto humanos), fúngicas e microbianas nativas ou de ocorrência natural no território nacional. A Lei causou impacto direto e imediato em todas as atividades de pesquisa científica e/ou bioprospecção envolvendo espécies nativas ou de ocorrência natural no Brasil. A obrigatoriedade de cadastro de projetos antigos, muitos dos quais já finalizados, causou grande alvoroço e preocupação junto à comunidade científica brasileira. Muitas Universidades e Instituições de Pesquisa criaram departamentos internos especializados na adequação dos projetos de pesquisa à nova legislação, buscando evitar a aplicação de multas tanto aos pesquisadores responsáveis, quanto às Instituições onde os projetos foram ou serão executados. Embora relativamente simples, o cadastramento das amostras ainda é a principal dificuldade relatada pelos pesquisadores. O correto cadastramento de amostras compostas (no caso de trabalhos de bioprospecção e metagenômica, por exemplo) e a previsão de repartição de benefícios, decorrentes da exploração econômica de produto acabado ou de material reprodutivo oriundo de acesso ao patrimônio, representam as maiores dúvidas apresentadas pelos pesquisadores. A regulamentação do acesso ao patrimônio genético apresenta-se como uma importante ferramenta de gerenciamento das pesquisas envolvendo a biodiversidade nacional. Entretanto, é fundamental que as políticas públicas de regulamentação não provoquem, por excesso de burocracia e falta de clareza, a inviabilização de projetos de pesquisa que tenham como característica inerente o acesso ao patrimônio genético de espécies nativas brasileiras.
Tear Film, Conjunctival and Corneal Modifications Induced by Glaucoma Treatment
Authors: Roberti Gloria , Tanga Lucia , Manni Gianluca , Riva Ivano , Verticchio Alice Chandra , Berardo Francesca , Carnevale Carmela , Oddone Francesco
Published: May 2019

Ocular surface disease is characterized by tear film instability and histopathologic and clinical changes of
the ocular surface. Glaucoma patients often suffer from ocular surface disease caused by the chronic use of
preserved medical treatment to reduce intraocular pressure. Benzalkonium chloride is the preservative most
frequently used in glaucoma medications. Its effect on tear film, conjunctiva and cornea and the consequences in
glaucoma management are discussed in this mini-review.
Immunoliposomes in Acute Myeloid Leukaemia Therapy: An Overview of Possible Targets and Obstacles
Authors: Singh Aditi , Myklebust Nikolai Norevik , Furevik Sarah Marie Vie , Haugse Ragnhild , Herfindal Lars
Published: May 2019

:

Acute Myeloid Leukaemia (AML) is the neoplastic transformation of Hematopoietic Stem Cells (HSC) and relapsed disease is a major challenge in the treatment. Despite technological advances in the field of medicine and our heightened knowledge regarding the pathogenesis of AML, the initial therapy of “7+3” Cytarabine and Daunorubicin has remained mainly unchanged since 1973. AML is a disease of the elderly, and increased morbidity in this patient group does not allow the full use of the treatment and drug-resistant relapse is common.

:

Nanocarriers are drug-delivery systems that can be used to transport drugs to the bone marrow and target Leukemic Stem Cells (LSC), conferring less side-effects compared to the free-drug alternative. Nanocarriers also can be used to favour the transport of drugs that otherwise would not have been used clinically due to toxicity and poor efficacy. Liposomes are a type of nanocarrier that can be used as a dedicated drug delivery system, which can also have active ligands on the surface in order to interact with antigens on the target cells or tissues. In addition to using small molecules, it is possible to attach antibodies to the liposome surface, generating so-called immunoliposomes. By using immunoliposomes as a drug-delivery system, it is possible to minimize the toxic side effects caused by the chemotherapeutic drug on healthy organs, and at the same time direct the drugs towards the remaining AML blasts and stem cells.

:

This article aims to explore the possibilities of using immunoliposomes as a drug carrier in AML therapy. Emphasis will be on possible target molecules on the AML cells, leukaemic stem cells, as well as bone marrow constituents relevant to AML therapy. Further, some conditions and precautions that must be met for immunoliposomes to be used in AML therapy will be discussed.
B7-H3 Immune Checkpoint Protein in Human Cancer
Authors: Flem-Karlsen Karine , Fodstad Øystein , Nunes-Xavier Caroline E.
Published: May 2019

B7-H3 belongs to the B7 family of immune checkpoint proteins, which are important regulators of the adaptive immune response and emerging key players in human cancer. B7-H3 is a transmembrane protein expressed on the surface of tumor cells, antigen presenting cells, natural killer cells, tumor endothelial cells, but can also be present in intra- and extracellular vesicles. Additionally, B7-H3 may be present as a circulating soluble isoform in serum and other body fluids. B7-H3 is overexpressed in a variety of tumor types, in correlation with poor prognosis. B7-H3 is a promising new immunotherapy target for anti-cancer immune response, as well as a potential biomarker. Besides its immunoregulatory role, B7-H3 has intrinsic pro-tumorigenic activities related to enhanced cell proliferation, migration, invasion, angiogenesis, metastatic capacity and anti-cancer drug resistance. B7-H3 has also been found to regulate key metabolic enzymes, promoting the high glycolytic capacity of cancer cells. B7-H3 receptors are still not identified, and little is known about the molecular mechanisms underlying B7-H3 functions. Here, we review the current knowledge on the involvement of B7-H3 in human cancer.
Chloroquinoline-3-carbonitriles: Synthesis and Reactions
Authors: Mekheimer Ramadan A. , Al-Sheikh Mariam A. , Medrasi Hanadi Y. , Bahatheg Ghayah A. , Sadek Kamal U.
Published: May 2019

We herein describe the first review which aims to focus soberly the various synthetic methods and chemical reactions of chloroquinoline-3-carbonitrile derivatives. The reactions are subdivided into groups that cover reactions of chloro substituent at 2 or 4 and 2,4 positions, as well as cyano substituent at 3 position and reactions which involve both groups. Most types of reactions have been successfully applied and used in the production of biologically active compounds.
PP2A Phosphatases Take a Giant Leap in the Post-Genomics Era
Authors: Bheri Malathi , Pandey Girdhar K.
Published: May 2019

Background:

Protein phosphorylation is an important reversible post-translational modification,
which regulates a number of critical cellular processes. Phosphatases and kinases work in a
concerted manner to act as a “molecular switch” that turns-on or - off the regulatory processes driving
the growth and development under normal circumstances, as well as responses to multiple stresses in
plant system. The era of functional genomics has ushered huge amounts of information to the framework
of plant systems. The comprehension of who’s who in the signaling pathways is becoming
clearer and the investigations challenging the conventional functions of signaling components are on a
rise. Protein phosphatases have emerged as key regulators in the signaling cascades. PP2A phosphatases
due to their diverse holoenzyme compositions are difficult to comprehend.

Conclusion:

In this review, we highlight the functional versatility of PP2A members, deciphered
through the advances in the post-genomic era.
Varlitinib Mediates Its Activity Through Down Regulating MAPK/EGFR Pathway in Oral Cancer
Authors: Usman Muhammad , Tanveer Fariha , Ilyas Amber , Zarina Shamshad
Published: May 2019

Background:

Oral Squamous Cell Carcinoma (OSCC) is a major sub-type of oral cancer
that shares 90% proportion of oral cavity cancers. It is declared as the sixth most frequent cancer
among all cancer types throughout the world. Higher morbidity in Asian countries is reported due to
frequent use of Smokeless Tobacco (SLT) products besides exposure to other risk factors. Hyperactivation
of epidermal growth factor receptors is a molecular event in many solid tumors including
oral cancer making them potential therapeutic targets.

Objective:

Current study was designed to explore the effect of varlitinib, a pan-HER inhibitor, on oral
cancer cell line. We investigated key regulatory genes in downstream pathway in response to drug
treatment. Furthermore, we also examined expression profile of these genes in malignant and healthy
oral tissue.

Method:

Gene expression pattern in drug treated and untreated cancer cell line along with OSCC tumor
samples (n=45) and adjacent normal tissues was studied using real time PCR.

Results:

In response to varlitinib treatment, significant suppression of oncogenes (IGF1R, MAPK1,
SFN and CDK2) was observed. Interestingly, mRNA expression level of CDKN1A and Akt1 was found
to be the opposite of what was expected. In case of malignant tissue, over expression of oncogenes
(IGF1R, Akt1, MAPK1, SFN and CDK2) with simultaneous down expression of tumor suppressor
genes (Tp53 and CDKN1A) was noted. STRING analysis indicated a strong association among differentially
expressed genes suggesting their combined role in carcinogenesis.

Conclusion:

In summary, our results indicate that varlitinib can be considered as a potential therapeutic
agent in oral cancer due to its antitumor potential.
Monobactams: A Unique Natural Scaffold of Four-Membered Ring Skeleton, Recent Development to Clinically Overcome Infections by Multidrug- Resistant Microbes
Authors: El-Shorbagi Abdel Nasser , Chaudhary Sachin
Published: May 2019

Background:

Monobactam antibiotics have been testified to demonstrate significant antibacterial activity especially the treatment of infections by superbug microbes. Recently, research has been focused on the structural modifications, and new generation of this privileged natural scaffold.

Objective:

Efforts have been made to discover the structure-antibacterial relationship of monbactams in order to avoid the aimless work involving the ongoing generated analogues. This review aims to summarize the current knowledge and development of monobactams as a broad-spectrum antibacterial scaffolds. The recent structural modifications that expand the activity, especially in the infections by resistant-strains, combinational therapies and dosing, as well as the possibility of crosshypersensitivity/ reactivity/tolerability with penicillins and cephalosporins will also be summarized and inferred. Different approaches will be covered with emphasis on chemical methods and Structure- Activity Relationship (SAR), in addition to the proposed mechanisms of action. Clinical investigation of monobactams tackling various aspects will not be missed in this review.

Conclusion:

The conclusion includes the novels approaches, that could be followed to design new research projects and reduce the pitfalls in the future development of monobactams.
Recent Advances in Water Treatment Using Graphene-based Materials
Authors: Khaligh Nader Ghaffari , Johan Mohd Rafie
Published: May 2019

:

A variety of processes were reported for efficient removing of heavy metal from
wastewater, including but not limited to ion exchange, reverse osmosis, membrane filtration, flotation,
coagulation, chemical precipitation, solvent extraction, electrochemical treatments, evaporation,
oxidation, adsorption, and biosorption. Among the aforementioned techniques, adsorption/ion exchange
has been known as a most important method for removing heavy metal ions and organic pollutants
due to great removal performance, simple and easy process, cost-effectiveness and the considerable
choice of adsorbent materials.

:

Nanotechnology and its applications have been developed in most branches of science and technology.
Extensive studies have been conducted to remove heavy metal ions from wastewater by preparation
and applications of various nanomaterials. Nanomaterials offer advantages in comparison to other
materials including an extremely high specific surface area, low-temperature modification, short
intraparticle diffusion distance, numerous associated sorption sites, tunable surface chemistry, and
pore size. In order to evaluate an adsorbent, two key parameters are: the adsorption capacity and the
desorption property. The adsorption parameters including the absorbent loading, pH and temperature,
concentration of heavy metal ion, ionic strength, and competition among metal ions are often studied
and optimized.

:

Several reviews have been published on the application of Graphene (G), Graphene Oxide (GO) in
water treatment. In this minireview, we attempted to summarize the recent research advances in water
treatment and remediation process by graphene-based materials and provide intensive knowledge
of the removal of pollutants in batch and flow systems. Finally, future applicability perspectives are
offered to encourage more interesting developments in this promising field. This minireview does not
include patent literature.
Bridge Displacement Estimation using Tiltmeter Data
Authors: Panuntun Raka Bagus , Aminullah Akhmad , Suhendro Bambang , Wardana Panji Krisna
Published: May 2019

Structural Health Monitoring System (SHMS) works as an efficient platform for monitoring health condition and and deterioration of civil structures during long-term service periods. One of the sensors is currently applied to Soekarno Bridge is tiltmeter. Vertical displacement data are often required to reflect the overall response of bridge span, however the Soekarno Bridge does not have any displacement sensor. On the other hand, the displacement sensor is very costly compared to tiltmeter. A method is proposed to estimate bridge displacement using data that is collected through tiltmeter. The method is using interpolation and numerical integration to evaluate the displacement. The result shows that the result obtained from the proposed method is reliable with accuracy of displacement around 5 mm. Some recommendations for further implementation of the sensors are provided.
Rapid Lava Sand Filtration for Decentralized Produced Water Treatment System in Old Oil Well Wonocolo
Authors: Yogafanny Ekha
Published: May 2019

The Cepu Block Oil Field has been traditionally extracted since 2008 by the local community in Wonocolo. The oil well-produced gas and fluids consisted of crude oil and produced water. This oil production activity discharges high amounts of produced water. The fluids have been settled down in the sedimentation tank to gain the crude oil optimally. The remaining fluid called produced water has been discharged to the surface towards the river without any further treatment.  This activity led to the deterioration of environmental quality. This study aimed to analyze the performance of produced water treatment by rapid sand filtration by measuring the degree of turbidity removal under the specific condition on a laboratory scale using lava sand. The sedimentation was conducted in 3 hours of retention time following the real field condition of the oil production process by community in one sample well. The rapid sand filtration was conducted by a fixed bed column method with 0.2 cm of grain size. The sedimentation process followed by the rapid sand filtration in produced water treatment yielded the high efficiency of turbidity removal reaching 98.65 %. The rapid sand filter also worked excellently in turbidity removal attaining 96.48 % of efficiency. These results confirmed that the sedimentation already done by the community followed by the rapid sand filtration is promising decentralized technology to be applied in a remote area such as Old Oil Wells Wonocolo regarding turbidity removal.
Freezing Technology: Challenges and Prospects for Sustainable Development in Urban Infrastructure
Authors: Kanie Shunji
Published: May 2019

Ground freezing has been broadly applied to construction and maintenance works of infrastructures because of its environmental friendliness. Since freezing technology represented by ground freezing can improve the strength of soil as well as its water-tightness, it becomes an essential technology for construction and maintenance of urban infrastructures where the use of space in underground has already been highly integrated. In this paper, overview of the freezing technology is introduced with some important characteristics of freezing soil for practical application. In addition, freezing technology is used for interesting works which could not be completed without freezing, and the state of the arts in freezing technology is presented. A pipe-in-pipe, now the authors are developing, is an example to utilize the potential of frozen sand, and the effect of freezing is explained with experimental results.
Hibridization, Linguistic and Stylistic Innovation in Cameroonian Literature and Implications for Translation
Authors: Che Suh Joseph
Published: May 2019

Drawing from Cameroonian drama written in French and translated into English, this paper demonstrates how Cameroonian literature written in European languages and translated into other European languages is characterized by linguistic and stylistic innovation. It examines the reasons and motivations underlying this phenomenon, first from the perspective of the ambivalent situation of the Cameroonian and African writer writing not in his native language but rather in a European language, and secondly in the light of the prevailing literary creative trend and attitude of Cameroonian and, indeed, African writers in general. In this context, it is argued and posited that Cameroonian literary works are heavily tinted with linguistic and stylistic innovations such that the source texts actually intervene and exert considerable influence on the mode of their translation into the target language, particularly if the translator is to preserve the Cameroonian/African aesthetic which informs them and constitutes their driving force.
Complications and associated healthcare costs of transvenous cardiac pacemakers in Germany
Authors: Ludwig Saskia , Theis Cathrin , Wolff Claudia , Nicolle Emmanuelle , Witthohn Andreas , Götte Andreas
Published: May 2019

Aim:This study evaluated the occurrence and associated costs of pacemaker complications in Germany from 2010 to 2013.Patients & methods:Patients with ade novoor replacement implantation of a single or dual chamber pacemaker between 2010 and 2013 were followed for 12 months post-implant using German health insurance claims data. A case–control analysis was performed using propensity score matching to estimate the costs of complications.Results:Out of 12,922 implanted patients, 12.0% had a complication in the year following the implant. Complications related to lead and pocket were found in 10.2% of all implanted patients; infections occurred in 1.7% patients. Healthcare costs up to 36 months post complication were on average €4627 higher than for pacemaker patients without a complication.Conclusion:Pacemaker complications are common and represent a burden for patients and healthcare systems generating substantial costs. Most of the pacemaker complications involved the pacing lead or pacemaker pocket.
Alteraciones de salud en estudiantes de Licenciatura en Enfermería
Authors: Torres Magallanes Marisol , Guzmán Estrada Juan Martín , Legorreta Pérez Jorge David
Published: May 2019

<span style="font-family: "Calibri","sans-serif"; color: black; font-size: 11pt; mso-bidi-font-size: 5.5pt; mso-ascii-theme-font: minor-latin; mso-hansi-theme-font: minor-latin; mso-bidi-theme-font: minor-latin; mso-bidi-font-style: italic;">En este trabajo se identificaron las alteraciones de salud que presentan las y los estudiantes de la

<span style="font-family: "Calibri","sans-serif"; color: black; font-size: 11pt; mso-bidi-font-size: 5.5pt; mso-ascii-theme-font: minor-latin; mso-hansi-theme-font: minor-latin; mso-bidi-theme-font: minor-latin; mso-bidi-font-style: italic;">Licenciatura en Enfermería, que cursan el 6° semestre, debidas a la alta carga de trabajo. La sede considerada fue la Facultad de Estudios Superiores Iztacala (del 15 de febrero al 9 de mayo del presente año), donde se aplicaron encuestas analizadas por medio de graficas, identificando las alteraciones de salud que afectaron mayoritariamente a los estudiantes, encontrando datos similares a los planteados en base a muestra experiencia y en relación a otras investigaciones.

 

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SUMMARY

This paperwork contains identified health disorders detected in students of the Bachelor of Nursing enrolled in the 6th semester, due to high workload. The school in question is the School of Advanced Studies Iztacala “Facultad de Estudios Superiores Iztacala” (from February 15th  to May 9th , 2011), where the applied surveys were analyzed by means of graphs, identifying the main health disorders that affect students, finding similar data to those raised on the basis of experience showed in relation to other research.

 
El Metaparadigma, una limitante para el Conocimiento de la Enfermería.
Authors: Acevedo Peña Margarita , Guillén Cadena Dulce María , García Zeferino Ericka
Published: May 2019

Resumen:

La enfermería ha evolucionado en las ultimas décadas 

de forma importante, perfilándose como una ciencia 

independiente e interdisciplinaria con la medicina y 

otras, para que esto ocurra es necesario que todos los 

elementos de la estructura del conocimiento iniciando 

por el metaparadigma, sean interpretados, utilizados 

y aceptados por la comunidad de enfermeras, ¿Pero 

este concepto se está utilizando en la práctica de los 

diferentes escenarios de enfermería?, ¿Cuáles son 

los factores que influyen en su aplicabilidad?

Estas preguntas pueden conducirnos a revisar qué está 

pasando con el conocimiento de la enfermería respecto  

a si el metaparadigma limita el conocimiento. 

En el presente ensayo se analizan cuáles son 

los factores que influyen en la interpretación de 

los elementos del metaparadigma que limitan el 

conocimiento de Enfermería.

Palabras clave: Metaparadigma, Conocimiento, 

Enfermería

Abstract:

Nursing has evolved in recent decades an important, 

emerging as an independent and interdisciplinary 

science, medicine and others, for this to happen 

it is necessary that all elements of the structure 

of knowledge starting with the meta-paradigm, 

are interpreted, used and accepted by the nursing 

community, “but this concept is being used in the 

practice of nursing scenarios?, what are the factors 

that influence their applicability?, these questions 

can lead us to review what is happening with the 

knowledge about nursing, if the limits knowledge 

metaparadigm.

This essay analyzes the factors that 

influence the interpretation of the elements that limit  

metaparadigm nursing knowledge. 
Misión planes de estudio: Formar en Ética y Valores al estudiantado de Enfermería
Authors: Cuevas Guajardo Leticia , Guillén Cadena Dulce María , Valadez Díaz Dinora , Alonso Trujillo Javier
Published: May 2019

RESUMEN

En este mundo moderno en el que vivimos actualmente se ha hablado mucho de que la sociedad pasa por una “crisis de valores”; por suerte la profesión de enfermería ha conservado sus principios filosóficos fundamentados en el humanismo, aunque al correr de los años estos hayan cambiado; aun así, para el gremio de enfermería, siempre ha resultado importante conservar y apegarse a un “Código de Valores” que norma la profesión. El objetivo de esta investigación fue el de distinguir en los Planes de Estudio de diferentes universidades de México que imparten la Licenciatura en Enfermería la importancia que le brindan a formar en valores a sus estudiantes por medio de asignaturas en Ética, Axiología, Deontología o Humanismo o bien, que lo planteen en su descripción aunque no le den el nombre propiamente de Ética u otro con igual significado.

El 96.5% de los Planes de Estudio revisados citaron aspectos éticos y de valores en la formación que ofrecen a las y los estudiantes. Por lo que la misión de los Planes de Estudio revisados en cuestiones éticas se cumple.

PALABRAS CLAVE

Ética, valores, misión de planes de estudio.

SUMMARY

In this modern world in that we lived at the moment it has spoken much of which the society happens through a “crisis of values”; luckily the infirmary profession has conserved its philosophical principles based on the humanism, although when running of the years these have changed; even so, for the infirmary union, always it has been important to conserve and to become attached themselves to a “Code of Values” that norm the profession. The objective of this investigation was the one to distinguish in the Curricula of different universities from Mexico that distribute the Degree in Infirmary the importance that offers him to form in values to their students by means of subjets in Ethics, Axiollogy, Deontology or Humanism or, that raises it in their description although they properly do not give the name him of Ethics or another one with equal meaning.

In this Evaluativa Investigation the 96,5% of the reviewed Curricula mentioned ethical aspects and of values in the formation that offer to and the students. Reason why the mission shaped in the reviewed Curricula in ethical questions is fulfilled.

KEY WORDS

Ethics, Values, Mission, Curricula.
Percepción del cuidado de Enfermería en el paciente adulto
Authors: Segura Granados Karen Ivette , Miranda García Claudia Marcela , Guillén Cadena Dulce María
Published: May 2019

INTRODUCCIÓN. Enfermería es una profesión de carácter social que tiene como objetivo el cuidado integral de la persona, familia y comunidad; el cual se dirige al bienestar ofreciendo empatía, trato digno y creando lazos para compartir experiencias de vida mediante la percepción individual, la cual parte de un proceso que depende de la información que se recibe del mundo y las experiencias de quien lo recibe.

La presente investigación se realizó con el fin de reflexionar acerca de la importancia del cuidado, ya que éste repercute en el bienestar, la satisfacción y en una menor estancia hospitalaria del paciente. 

MARCO METODOLÓGICO. Investigación cualitativa, se utilizó el método fenomenológico y para la recolección de datos se utilizó la técnica de la Entrevista a profundidad con una guía de Preguntas tema biográficas, demográficas y de percepción para obtener la esencia del objeto de estudio. El análisis de datos se llevó a cabo a través de lo propuesto por S.J Taylor y R. Bogdan. HALLAZGOS. Los principales hallazgos encontrados fueron el cuidado de Enfermería que fue eficaz e ineficaz, el trato digno brindado al paciente, que se planteó como adecuado e inadecuado, donde salieron a relucir ambos casos, las actitudes profesionales

refiriéndose a la humanización y deshumanización, el apoyo emocional manifestado como la seguridad o inseguridad que los participantes sienten por parte del personal de enfermería.

DISCUSIÓN. Poblete (2007), menciona que el cuidado se ve afectado por los sistemas institucionales y la impregnación de un modelo biomédico dejando de lado los aspectos que se involucran en el holísmo lo que conlleva a la pérdida de la autonomía y humanización; aunque Bautiste (2008) habla de que las habilidades, relaciones enfermera-paciente y el trato personalizado optimizará la percepción del cuidado.
Importancia de la producción de endorfinas para evitar estrés y síndrome metabólico
Authors: Cuevas guajardo Leticia
Published: May 2019

RESUMEN

El estrés crónico y sostenido tiene una estrecha relación con el Síndrome Metabólico, ninguna de estas dos afecciones son convenientes para la salud de las personas ya que son factores de riesgo para desarrollar enfermedad cardiovascular. Por otro lado, las endorfinas son sustancias secretadas en el encéfalo que pueden contrarrestar los daños producidos tanto por el estrés, como por el Síndrome Metabólico, y tienen la ventaja de ser drogas naturales que producen una sensación de analgesia y bienestar. Una forma muy sugerida en la actualidad para producir endorfinas es el ejercicio físico moderado y  constante. Este trabajo presenta los aspectos más relevantes acerca del estrés crónico, el Síndrome Metabólico y las endorfinas. Se sintetizó la información más importante para el lector y que éste pueda apreciar los beneficios de estimular la secreción de estas drogas naturales que poseemos, como una forma de prevenir y curar los trastornos ocasionados por el estrés permanente. 

Palabras clave: Endorfinas, bienestar, salud, estrés crónico.

ABSTRACT

Sustained and chronic stress has one close relationship with metabolic syndrome, any of these two conditions are suitable for the health of the people they are risk factors for developing cardiovascular disease. On the other hand, the endorphins are substances secreted in the brain that may counteract damage caused by stress, both by the metabolic syndrome, and have the advantage of being natural drugs that produce a feeling of well-being and analgesia. One way very suggested today to produce endorphins is steady and moderate physical exercise. This paper presents the most relevant aspects of chronic stress, metabolic syndrome and endorphins. It summed up the most important information for the reader and that it can appreciate the benefits of stimulating the secretion of these natural drugs that we have, as a way of preventing and curing disorders caused by permanent stress. 

Key words: Endorphins, welfare, health, chronic stress. 