bluuebunny/crossref_metadata_2025 huggingface dataset:
The YOLO model that still excels in document layout analysis
Authors: Deng Qilin , Ibrayim Mayire , Hamdulla Askar , Zhang Chunhu
Published: August 2023

Document layout analysis can help people better understand and use the information in a document. However, the diversity of document layouts and considerable variation in aspect ratios among document objects pose significant challenges. In this study, we designed the Multi-Convolutional Deformable Separation (MCDS) module as the main structure of the network, using the YOLO model as a baseline. Integration of this module into the Backbone and Neck layers enhances the image feature extraction process significantly. Moreover, we incorporate ParNet-Attention to direct the network's focus toward document objects through parallel networks, thereby facilitating a more exhaustive feature extraction. To optimize the model's predictive potential, the Decouple Fusion Head (DFH) is employed within the Head layer. This technique leverages multi-scale features based on the decoupled head, thereby enhancing the accuracy of predictions. Our proposed model achieves remarkable performance on three distinct public datasets with varying characteristics, namely ICDAR-POD, PubLayNet, and IIIT-AR-13K. Notably, in ICDAR-POD, both IoU$_{0.6}$ and IoU$_{0.8}$ achieve the optimal mean Average Precision (mAP), 96.2 and 94.4, respectively.
Time-Varying Impact of US Monetary Policy Spillovers on Small Open Economies: Evidence from Indonesia
Authors: Saba Danladi N , Sanusi Aliyu Rafindadi
Published: August 2023

This study examines the impact of the US monetary policy spillover on Indonesia’s macroeconomic and financial variables using quarterly data for the period 2000–2020 for both domestic and US variables. We use the impulse responses obtained from an estimated Time-Varying VAR model with stochastic volatility to examine the response of real GDP, inflation, exchange rate, stock market return, and monetary policy rate to US monetary policy shock. We find that US monetary policy spillovers, on average, boost Indonesia’s real GDP, stock market returns, and bilateral exchange rate vis a vis the US Dollar but also trigger domestic inflation beyond what Indonesia’s policy reaction could counteract. However, there are considerable differences in the response of the variables to easing and tightening shocks, on the one hand, and conventional vs unconventional monetary policy, on the other. Finally, we found substantial time variation corresponding to major global events, including the Global Financial Crisis and implementation of unconventional monetary policy, the taper tantrum of 2013-2014, and the great lockdown in the wake of the Covid-19 pandemic in 2019-2020.
Quality of breaking bad news to patients diagnosed with neoplasia of the uterine cervix
Authors: Blanckenburg Pia , Köhler Christhardt , Petzel Anja , Jülicher Anne , Schneider Viola , Schneider Achim
Published: August 2023

Objective
Little is known about the quality of receiving bad news (BN) for women diagnosed with cervical neoplasia. We evaluated adherence to the SPIKES protocol in three cohorts of women with different stages of the disease and treatment modalities.
Patients and Methods
We included women with cervical cancer who underwent radical vaginal trachelectomy (RVT group, n=110), radical hysterectomy or chemo-radiation (HE/RCT group, n=101), and women with CIN 3 treated by loop excision (CIN group, n=108). We asked the participants about how they received the bad news delivery in reality and how they would envision an ideal communication process based on the main items of the SPIKES protocol. The participants filled out a questionnaire with 38 items of the Marburg Breaking Bad News (MABBAN) Scale representing the six SPIKES subscales.
Results
Only 55% of all patients reported being satisfied with their BBN experience. The following factors were considered important by 90% of the patients: an undisturbed atmosphere, taking enough time, coherent explanation of the disease, and the possibility to ask questions. However, the reality of their experiences fell significantly short of their expectations. Asking about the patient's knowledge of the disease, addressing their concerns, allowing them to show emotions, providing clarity about the change in quality of life, informing them about alternative therapies, and involving them in further planning were also significantly lacking in the actual BBN encounters compared to the patients' preferences. The experience of RVT patients was more negative compared to the HE/RCT patients (p = 0.036). The CIN patients had an overall satisfactory impression (p<.0001).
Conclusion
The process of breaking bad news in German women diagnosed with cervical neoplasia requires substantial improvement. The SPIKES protocol can be used as a guideline for enhancement but should be supplemented by incorporating a second interview and triadic consultation as the norm rather than the exception. Continuous monitoring and improvement of the quality of BBN is recommended for all oncologic institutions, utilizing the MABBAN questionnaire as a valuable tool.
Recrudescent plasmodium falciparum malaria after head trauma: a case report with novel clinical perspective
Authors: Liu Shiwen , Wang Xing , Ni Qian , Lu Yi , Wu Danni , Wu Zeqian , Fu Bin , Sun Xi
Published: August 2023

Malaria is a common infection disease in tropical regions, among which cerebral malaria caused by Plasmodium Falciparum remains an enormous threat. Recrudescence of Plasmodium falciparum malaria makes it hard to eliminate the disease of malaria. Many factors that can lead to immune suppression are believed to have the function of causing malaria recrudescence, but whether traumatic brain injury can trigger it remains unclear. Here we present a Plasmodium Falciparum malaria patient who had explicit traumatic brain injury history just before the onset of his symptoms of cerebral malaria. Besides, the progression of his cerebral malaria is much more rapid than normal. Throughout the case report we discuss a new provoking factor that may promote the recrudescence of Plasmodium Falciparum malaria and propose a novel perspective to avoid or reduce acute kidney injury in patients with cerebral malaria.
Fiscal Decentralization and Structural Involution in Developing Countries
Authors: Wiryawan Bangkit A.
Published: August 2023

Fiscal decentralization has been labeled as the silent change in the world's development. The main purpose of this policy is to increase growth and equality in country's sub-national level as well as promote openness and accountability. This in turn would lead to productive structural transformation when combined with industrial policy. However, my finding suggests that the reversal is true. Using data derived from IMF's Government Financial Statistics for the period between 1995 and 2017, it is found that fiscal decentralization has led to structural involution where the output share of agriculture increased at the cost of declining share of other sectors, particularly the industry sector. The result is particularly robust for low and lower-middle income country groups as well as under different estimation method. The phenomenon goes in line with premature decentralization narrative. These findings call, among others, for the prior need of a strong institutional capacity at the local level in order to mitigate local elite capture and rent-seeking. With stronger central-local collaboration, vertically-coordinated industrial policy between multi-level of governments could kick in to support productive transformation.
JEL: E26, H50, H72, O11
Coexistence of Plasmid-mediated Quinolone Resistance (PMQR) and Extended Spectrum β-lactamases (ESBLs) genes among clinical Pseudomonas aeruginosa isolates in Egypt
Authors: Abdelrahim Soha S. , Hassuna Noha A. , Waly Nancy G. F. M. , Kotb Dalia N. , Abdelhamid Haitham , Zaki Shaimaa
Published: August 2023

Background: The rapid increasing prevalence of resistant P. aeruginosato widely used broad spectrum antibiotics as fluroquinolones and cephalosporins has become a matter of serious concern. Plasmid-mediated quinolone resistance (PMQR) have been recently identified as an emerging clinical problem among extended spectrum β-lactamases (ESBLs) producing gram negative bacteria.
Methods: A total of 56 P. aeruginosa strains isolated from 330 patients with different infections were investigated for fluoroquinolone resistance phenotypically. Molecular methods were used to screen for 6 PMQR determinants among the fluoroquinolone-resistant isolates and for 3 ESBL genes among cephalosporin resistant isolates.
Results: Overall, 22/56 (39.3%) of studied P. aeruginosa isolates were resistant to one or both tested fluoroquinolones. PMQR-producing P. aeruginosa isolates were identified in 20 isolates (90.9%). The acc(6ʹ)-1b-crwas the most prevalent PMQR gene (77.3%). The qnr genes were occurred in 72.7% of isolates. The qnrA gene was the most predominant 54.5%, followed by qnrS gene 27.3%, then each of qnrB and qnrC22.7%. The qepA was not detected in any isolate. The remarkable result of the current study was the high co-carriage of PMQR genes among the quinolone resistant isolates. Association of acc(6ʹ)-1b-cr with qnr genes was detected in 65% of positive PMQR isolates. Gene profiles carrying more than 2 PMQR genes were prevalent in P. aeruginosa isolates from wound and ear discharge. The ESBL genes were detected in 52% of cephalosporin resistant P. aeruginosa isolates. The most frequent ESBL gene was blaCTX-M(76.9%) followed by blaTEM (46.2%). Co-carriage of blaTEM and blaCTX-Mwas found in 23%. No isolates carried blaSHV. The ESBL genes positive isolates showed a significant higher resistance to non-beta lactam antibiotics. Regarding co-existence of PMQR and ESBL genes, at least 1 ESBL gene was found in 75% of PMQR-positive isolates. The acc(6ʹ)-Ib-cr gene showed the highest association with ESBL genes followed by qnrA gene. The correlation matrix of detected PMQR and ESBL genes indicated overall positive correlations. The strongest and highly significant correlation was between qnrAand acc(6ʹ)-Ib-cr (r = 0.602) and between qnrA and blaCTX-M (r = 0.519).
Conclusion: The worldwide increased prevalence of ESBL producing and fluoroquinolone resistant P. aeruginosa strains became a serious threat to public health and a great challenge to treatment options. Studied P. aeruginosa isolates exhibited coexistence of PMQR and ESBL genes.
Evolving Parameters of Shewhart Control Chart from Present-day Industrial Engineering Perspective
Authors: Sandeep  , Mukhopadhyay Arup Ranjan
Published: August 2023

The implementation of control charts for controlling processes based on statistical principles often requires answering questions like what should be the sample size (n), the sampling interval (h), and the control limits’ multiplier (k). This work, inspired by Duncan and other authors like Gibra, I.N. and Saniga, E.M., etc., has evolved from certain practical considerations in an industry. Duncan in his economic design considered parameters like loss due to false alarm, the average cost of finding an assignable cause, the hourly cost of process control, and average income from in-control and out-of-control processes. However, the proposed model has considered additional parameters like production rate, sampling cost, sample preparation cost, testing cost, energy cost, consumables cost, and reporting cost from the perspective of production engineering. The economic model thus developed has been tailored to encapsulate the journey from Duncan to the contemporary period. The model has been appropriately optimized to determine n, h, and k. The effectiveness of the procedure has been demonstrated through numerical examples, comparative enumeration, and sensitivity analysis. The work is expected to transcend the much-hyped divide between theory and practice in the parlance of statistical process control.
Impact of Concrete-Pictorial-Abstract Approach with Collaborative Lesson Research on Year Four Pupils’ Proficiency in Volume
Authors:   Institut Pendidikan Guru Kampus Pulau Pinang, 11700 Gelugor, Pulau Pinang, Malaysia, Shafiee Mohd Shafian , Cheng Meng Chew ,   School of Educational Studies, Universiti Sains Malaysia, 11800 USM Pulau Pinang, Malaysia,   School of Education, Humanities & Social Sciences, Wawasan Open University, 54, Jalan Sultan Ahmad Shah, 10050 George Town, Pulau Pinang, Malaysia
Published: August 2023

This study aimed to determine the impact of concrete-pictorial-abstract (CPA) approach with collaborative lesson research (CLR) on Year Four pupils’ proficiency in volume. The counterbalanced research design, which consisted of three different groups of year four pupils with three treatments applied to each group, was used with the Proficiency in Volume Test (PVT) administered before and after each of the three CLR cycles. Cluster sampling was used to select three groups of 115 Year Four pupils consisting of 59 males and 56 females. PVT consisted of five questions based on the five strands of proficiency in volume: Q1 (conceptual understanding), Q2 (procedural fluency), Q3 (strategic competence), Q4 (adaptive reasoning), and Q5 (productive disposition). It has a total score of 15 and the indicators of proficiency in volume are low proficiency (0–4), average proficiency (5–10), and high proficiency (11–15). The data were analysed using the paired-sampleCLR cycles-test and one-way ANOVA in SPSS version 24. The results of the paired-sample t-test showed that there was a significant difference between the mean scores of the pre- and post-tests for each CLR cycle. The results of the paired-sample t-test for cube in the first, second and third cycles of CLR were: t = –6.74, df = 37, p < 0.05; t = –19.82, df = 37, p < 0.05; and t = –22.10, df = 38, p < 0.05, respectively. The results of the paired-sample t-test for cuboid in the first, second and third cycles of CLR were: t = 3.15, df = 37, p < 0.05; t = 9.87, df = 38, p < 0.05; and t = 20.76, df = 37, p < 0.05, respectively. The results of oneway ANOVA showed that there was a significant in the post-test mean scores between the first, second and third CLR cycles. The result of one-way ANOVA for cube was F (2,112) = 53.32, p < 0.05, while for cuboid it was F (2,112) = 71.16, p < 0.05. The CLR cycles carried out helped teachers in developing better teaching plans based on the CPA approach as well as enhancing Year Four pupils’ proficiency in volume.
DIAGNOSTICO DE LOS SISTEMAS AXIOLOGICOS O SISTEMA DE CREENCIAS ASOCIADOS A LA ETICA Y LOS VALORES PARA LA EDUCACION CIUDADANA EN ANTICORRUPCION: CASO UNIVERSIDAD AUTONOMA DE CAMPECHE
Authors:   Ph in Education Sciences, Academic Researcher, Faculty of Administration and Finance, Autonomous University of Campeche., Frine Moguel Marin Susana , Alberto Perez Canul Carlos ,   Ph in Administration Sciences, Academic Researcher, Faculty of Administration and Finance, Autonomous University of Campeche., Monserrat Llanes Chiquini Charlotte ,   Ph in Administration Sciences, Academic Researcher, Faculty of Administration and Finance, Autonomous University of Campeche., Manuel Patron Cortes Roger ,   Ph in Administration Sciences, Academic Researcher, Faculty of Administration and Finance, Autonomous University of Campeche., Tania del Carmen Tuyub Ovalle M.C. ,   Master in Psicolgy Sciences, Academic Researcher, High School , Autonomous University of Campeche., Concepcion Mex Alvarez Diana ,   Ph in Administration Sciences, Academic Researcher, Faculty ofengineering, Autonomous University of Campeche.
Published: August 2023

The present work seeks to visualize, from a diagnosis of The present work seeks to visualize, from a diagnosis of values and axiological beliefs, to reorient the gaze so that education not only has its sights set on solving the problems that children and young people live in the present, such as desertion, low academic performance or Bullying. It is important to look to the near future in which children and young people exercise an anti-corruption citizenship that requires their responsible and informed participation. Considering that corruption in the educational system itself generates an education without quality, incomplete and that perpetuates corruption in a vicious cycle that is very discouraging, but little has been studied and therefore corrected. El presente trabajo busca visualizar a partir de un diagnostico de valores y creencias axiologicas reorientar la mirada para que la educacion no solo tenga la mirapuesta en resolver los problemas que viven los ninos y jovenes en el presente como ladesercion, el bajo rendimiento academico o el acoso escolar. Es importante mirar unfuturo proximo en el que ninos y jovenes ejercen una ciudadanÃƒÂ­a anticorrupcion que lesexige participacion responsable e informada. Considerando que la corrupcion en el propio sistema educativo genera una educacion sin calidad,incompleta y que perpetua la corrupcion en un ciclo vicioso que mucho desalienta, pero poco ha sido estudiado y por ende corregido.
CLINICAL STUDY ON ACUTE APPENDICITIS INCORPORATING MODIFIED ALVARADO SCORE AND ABDOMINAL ULTRASOUND
Authors:   Senior Resident Department of General Surgery, JSS Medical College, Mysore-570004., Swamy Mahadeva , a Vishal ,   Senior Resident Department of General Surgery, RIMS, Raichur-584102., b Bhuvaneshwari ,   Senior Resident Department of General Surgery, SIMS, Shimoga-577201.
Published: August 2023

Acute appendicitis is one of the most common acute abdominal surgical emergencies the diagnosis of which is often challenging. If there is a delay in the diagnosis and prompt action is not taken, it may lead to perforation and other complication. Many scoring systems have been devised for the diagnosis of appendicitis, among which Modified Alvarado score is being used widely. Ultrasound also has gained importance in recent years. Our study aims in combining the use of Modified Alvarado score and USG in the diagnosis to bring down the rate of negative appendicectomies. Aimof The Study 1. To evaluate the sensitivity of the use of modified Alvarado scoring system and ultrasound in the diagnosis of acute appendicitis 2. To reduce the rate of negative appendicectomy. Materials & Methods: This study was done in 100 patients admitted in Navodaya Medical College Hospital from November 2019 to May 2021. All patients chosen on purposive sampling basis who present with right lower quadrant pain. Preoperatively, modified Alvarado score and abdominal ultrasound are assigned to those included in the study. Intraoperative findings and histo-pathological reports are followed up and the results are compared with modified Alvarado score and abdominal ultrasound. Results 1. In our study, the sensitivity of Modified Alvarado score in diagnosing Acute Appendicitis in the score range of 1-4 is 60%, so 6 out of 10 patients were confirmed with Acute Appendicitis. 2. In the score range of 5-7, out of 26 patients, 24 patients were confirmed with Acute Appendicitis using HPE having 92.3% sensitivity. 3. In the score >7, out of 64 patients , 63 patients had Acute Appendicitis confirmed with HPE and the sensitivity of HPE was the highest among this score range and its found to be 98.43%.The remaining 7 patients had normal appendix. 4. In our study, the sensitivity of USG Abdomen in diagnosing Acute Appendicitis was 95.83% in the score range of 5-7, 71.42% in score range of >7 and 66.6% in score range of 1-4.Out of 100 patients, USG abdomen showed positive result for Acute Appendicitis in only 72 patients when compared to HPE which showed 93 patients with Acute Appendicitis. Interpretation & Conclusion: Modified Alvarado scoring system is the better indicator for confirmation of diagnosis of Acute Appendicitis in the clinical setting rather than relying on USG abdomen imaging modality of investigation for diagnosing and treating the patient with Acute Appendicitis. When we incorporate both Modified Alvarado Scoring system and USG abdomen then we can diagnose Acute Appendicitis with accuracy close to HPE diagnosis of Acute Appendictis.
Akdeniz’deki Türk Hâkimiyetinin Görsel Temsili: Tuvallerde Preveze Deniz Zaferi
Authors: IŞIK YAYLA Rumeysa
Published: August 2023

Galibiyet veya mağlubiyetlerle sonuçlanan Osmanlı savaşlarının tasvir edilmesi, resim sanatı içerisinde nesiller boyu sürdürülen geleneğin bir parçasını oluşturmaktadır. İnsanlar geçmişte yaşanan olayları her ne kadar yazılı kaynaklardan öğrenmiş olsalar da dünyada iz bırakan gelişmeleri, bilhassa da savaşları zaman zaman bu tür betimlemeler aracılığıyla zihinlerinde canlandırmışlardır. Bu durum, kahramanlık fikriyle beslendiğinde yerini hamasî bir imgeye bırakmıştır. Bunun en belirgin yansımalarını, Türk resminde Preveze Deniz Zaferi (1538) konulu tuvallerde görmek mümkündür. Türklerin Akdeniz’de üstünlük kurmalarını sağlayan en büyük donanma savaşlarından biri olarak tarihe geçen bu mücadelenin görsel belge niteliğine dönüşmesi, bu resimler sayesinde gerçekleşmiştir. Çünkü Osmanlıların yenilmezliğini zihinlere kazıyan bu imaj, güçlü Türk imgesinin doğuşunda önemli role sahiptir. Aynı zamanda Osmanlı tarihsel anlatısına görsel açıdan büyük katkı sağlamaktadır. Üstelik ilk ürünlerini de 19. yüzyılın ortalarından itibaren vermeye başlamıştır. Fakat Preveze Deniz Muharebesi’nin bu alandaki önemi, bir Türk ressamın fırçasından çıkan en erken tarihli Osmanlı savaş tablosunu resim sanatına kazandırmış olmasıdır. Bu makalede ise Preveze Zaferi temalı tablolar üzerinden Osmanlı Devleti’nin Akdeniz’deki hâkimiyet imajının görsel unsurları tartışılacaktır.
Theoretical Studies of Xanthates in Heavy Metal Complexation: Understanding the Structural, Thermochemical, and Electronic Aspects
Authors: de Miranda Daniella , Quintal Susana , Ferreira Glaucio
Published: August 2023

Heavy metals have been widely discussed as a significant cause of environmental disasters in recent decades. One of the main focuses has been exploring agents and mechanisms capable of removing these metals from nature. Under this perspective, xanthates have been studied as sequestering agents of these metals in aqueous environments. In this theoretical study, complexes of cadmium(II) and mercury(II), with different coordination modes and geometric isomers of the xanthate ligands (n-propyl, n-butyl, and n-pentyl xanthates), were evaluated using density functional theory. To verify the versatility of coordination modes of the xanthates, monodentate and bidentate structures were optimized. For these compounds, structural, thermochemical, and electronic parameters were studied. The thermochemical results showed that all complexes are formed through exothermic and spontaneous processes. Electronic analysis showed that the mercury(II) complexes have a higher covalent character of the Hg-S bond, in contrast with the cadmium(II) complexes, which exhibited a higher ionic character of the Cd-S bond. Through the analysis of the natural bond orbitals, the Lewis acid-base nature of these complexes was confirmed and corroborated by the softness calculations, with the participation of the p orbitals of the sulfur and s orbitals of the metal centers.
İğde Çekirdeklerinden Elde Edilen Biyokömür ve Demirle Modifiye Edilmiş Biyokömür Kullanılarak Metil Mavisinin Sulu Çözeltiden Uzaklaştırılması
Authors: MORAL Emel , GÖDE Fethiye
Published: August 2023

Sürekli büyüyen endüstri alanları çevre ve su kirliliğine sebep olmaktadır. Su kirleticilerin sebeplerinden biri de geri kazanılmadan çevreye bırakılan boyar maddelerdir. Bu çalışmada iğde çekirdeklerinden biyokömür ve nanomanyetik biyokömür elde edilmiş, elde edilen biyokömürler anyonik bir boya olan metil mavisini sulu ortamdan uzaklaştırmak için kullanılmıştır. pH, başlangıç metil mavisi konsantrasyonu, sıcaklık, adsorban madde miktarı ve zaman değişiminin adsorpsiyon sürecine etkileri incelenmiştir. Maksimum adsorpsiyon kapasitesi biyokömür (b-EA) için 55.249 mg/g ve nanomanyetik biyokömür (mb-EA ) için 66.225 mg/g bulunmuştur. Adsorpsiyon izotermleri incelendiğinde her iki adsorbanında Langmuir adsorpsiyon izotermine (b-EA için R2=0.963, mb-EA için R2=0.991) daha uygun olduğu görülmüştür. Kinetik verilere göre her iki adsorban için adsorpsiyon hızı yalancı ikinci derecedendir. Ayrıca negatif ΔG değerleri adsorpsiyon sürecinin kendiliğinden, pozitif ΔH değerleri ise endotermik olarak gerçekleştiğini göstermektedir.
Cu Nanoparçacık İçeren Polikaprolakton Nanofiberlerin Antimikrobiyal Aktiviteleri
Authors: SAKİR Menekse , KİREMİTLER Nuri Burak , CEYLAN Ahmet
Published: August 2023

Askorbik asit ve CTAC yardımı ile ıslak kimyasal yöntem kullanılarak Cu nanoparçacıkların sentezi başarılı bir şekilde gerçekleştirildi. Elektron mikroskobu ile morfolojileri karakterize edilen nanoparçacıkların 578 nm civarında bir absorbans bandına sahip olduğu görüldü. Polikaprolakton (PCL) içerisine homojen bir şekilde dağıtılan Cu nanoparçacıklar ile elektroeğirme yöntemiyle ortalama 624±216 nm çapında nanofiberler elde edildi. PCL/Cu nanofiberlerin Staphylococcus aureus ve Escherichia coli bakterileri ile Candida albicans türü üzerindeki antimikrobiyal aktiviteleri incelendi. Nanolifler, sahip oldukları yüksek yüzey alanı sayesinde kontrol örnekleri ile kıyaslanabilir bir antimikrobiyal zon çaplarına sahip oldukları görüldü. Elde edilen PCL/Cu nanofiberlerin açık yaralarda kullanılan yara bandı veya bandaj gibi malzemelere, tıbbi tekstil ürünlerine entegre edilerek antimikrobiyal aktivitenin engellenmesi açısında faydalı olacağı düşünülmektedir.
Contrasting Approaches to Language, Meaning, and Knowledge in Advaita Vedanta and the Western Literary Traditions
Authors:   Amity School of Languages, Amity University, Lucknow, Garg Aayushee
Published: August 2023

The present research article undertakes a comprehensive examination of contrasting approaches to language and meaning, topics that have engendered contemplation and discourse across a range of disciplines including literature, philosophy, and linguistics. The article commences by delving into the foundational disparities between Indian and Western literary theories concerning the intricate relationship binding knowledge and meaning. While the Western tradition concentrates predominantly on interpreting textual meaning, treating literary works as subjects for analysis and critique, the Indian tradition perceives concepts and ideas within texts as indirect indicators of reality and self-realization. The ancient Indian school of thought, Advaita Vednata, presents a distinctive viewpoint on the dynamic interplay between language and meaning. The article further dissects the distinct attributes of the seemingly paradoxical and contradictory language prevalent in classical Indian texts. Through this exploration, it strives to uncover the methodology of constructing meaning as employed within the framework of Advaita Vednata. This analysis is juxtaposed against the approach to linguistic interpretation prevalent in the Western literary tradition—a tradition largely rooted in the empirical world. Advaita Vedanta places significance on direct experience or anubhava, prioritizing it over transmitted knowledge, and acknowledges that the true essence of the self transcends human comprehension. By navigating the quandary of defining literary language, elucidating the process of meaning-making in Western literary theory, delving into Advaita Vednata philosophy, and studying the role of language in representing the essence of the self, this research aspires to contribute meaningfully to the ongoing discourse in the areas of literary criticism and philosophical studies.
On the Perceptibility of Motion: An Inquiry from the Indian Philosophical Traditions
Authors:   Department of Humanistic Studies, IIT (BHU), Varanasi, Bhandari Manoj , Bhat Shruti Krishna ,   Indian Institute of Technology, Bombay, Dhital Vishwanath ,   Department of Humanistic Studies, IIT (BHU), Varanasi
Published: August 2023

This paper discusses an important issue regarding the concept of motion from the perspective of Indian philosophical traditions. We can recognise two camps in Indian philosophical schools regarding the epistemic means (pramana) through which one cognises motion. Some Indian philosophical schools claim that motion is completely imperceptible and one infers motion by perceiving contact and separation of an object with another object or space. Among these schools, we have considered Patanjali and Ramanuja (the author of Tantrarahasya) as the main advocators of this position. The other group claims that motion is perceptible and we infer motion only when the object possessing the motion is not perceptible. Supporters of this position are mainly the Nyaya-Vaisesika school and Narayanabhatta the author of Manameyodaya. While summarising and critically analysing these positions, we support the view that motion is perceptible by showing the following: (1) The position that motion is non-perceptible leads to some ontological issues (2) The position that motion is perceptible is more economical and simpler.
Sepsis por Candida lusitaniae en un paciente con adenocarcinoma gástrico: reporte de un caso
Authors: Pertuz-Meza Yolima Berena , Gonzalezrubio-Altamar Carlos , Cabas-De La Cruz Lina
Published: August 2023

La infección por Candida lusitaniae constituye una entidad poco frecuente con una prevalencia del 1% en el grupo de especies asociadas, además ha sido reconocido como un patógeno asociado a las infecciones adquiridas en la atención de salud en los pacientes de gravedad e inmunosuprimidos. Se presenta el caso de un paciente de 55 años con historia de ingreso hospitalario por dolor abdominal localizado en epigastrio, que se acompañaba de náuseas, vómitos, sensación de llenura, melenas, anorexia, y pérdida de peso, diagnosticada por estudios imagenológicos e histopatológicos con carcinoma gástrico avanzado, la cual desarrolló una sepsis por C. lusitaniae, se obtuvo un fungigrama y se dio manejo con fluconazol obteniendo una evolución satisfactoria en la paciente. Se concluye caso presentado demuestra que las características clínicas de esta especie se presentan acordes a la historia natural de la sepsis.
Complicaciones obstétricas y parámetros inmunológicos en gestantes seropositivas al VIH
Authors: Urdaneta-Machado José Ramón , Breuker-Mata Isabel
Published: August 2023

Introducción: las gestantes seropositivas al HIV pudiesen presentar diferentes complicaciones en el embarazo relacionadas tanto con su estado inmunológico como con la terapia retroviral. Objetivo: relacionar los parámetros inmunológicos con las complicaciones obstétricas presentadas por gestantes seropositivas al Virus de la Inmunodeficiencia Humana (VIH) atendidas en una maternidad venezolana. Método: estudio correlacionar retrospectivo, donde se estudió una muestra de 161 gestantes seropositivas al VIH; analizándose complicaciones obstétricas, contaje de CD4+ y carga viral. Resultados: las patologías maternas más frecuentes fueron: anemia (57,76%); mientras que de las complicaciones fetales y ovulares prevalecieron el bajo peso al nacer (13,04%) y rotura prematura de membranas (13,04%), respectivamente. Se evidenció una mayor y significativa frecuencia de morbilidades en las mujeres con CD4+= 200-499 células/ml y carga viral >1.000 copias/ml para la mayoría de las patologías; un contaje de CD4+ más bajo se asociaba con un riesgo altamente significativo de presentar patologías como anemia (OR= 14,44; IC95% 05,94-35,08), bajo peso al nacer (OR= 5,94; IC95% 02,05-17,20) e infección urinaria (OR= 3,38; IC95% 1,74-6,55). La carga viral no se asoció a mayor riesgo de complicaciones obstétricas. Conclusiones: la infección por el VIH se asocia a un mayor riesgo de complicaciones obstétricas en relación al estado inmunológico.
resposta de Habermas à crìtica de Arendt à noção de direitos humanos
Authors: Feldhaus Charles
Published: August 2023

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Habermas, estado de direito e polìtica do reconhecimento
Authors: Feldhaus Charles
Published: August 2023

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Implications of Herbal Components in the Treatment of Neurological
Disorders
Authors: Ali Daud , Verma Swati , Malviya Rishabha , Mishra Shuchita , Sundram Sonali
Published: August 2023

Herbal components have been explored as a potential alternative treatment for neurological
disorders due to the limitations and potential adverse effects of conventional treatments. Alzheimer’s
disease is the most prevalent progressive human neurodegenerative condition marked by
senile plaques and neurofibrillary tangles as well as gradual cognitive impairments; the most prominent
of which is memory loss. Different therapy techniques incorporating synthetic and herbal
approaches are being employed against AD based on the knowledge of the disease process. Commonly
used herbal components, such as Ginkgo biloba, Bacopa monnieri, Withania somnifera,
Passiflora incarnata, Rhodiola rosea, and Curcuma longa, have been shown to improve symptoms
and cognitive function in individuals with neurological disorders, such as Alzheimer’s disease, Parkinson’s
disease, and multiple sclerosis. However, more research is needed to fully understand the
efficacy, safety, and potential interactions with other medications. By continuously exploring and
researching the use of herbal components for neurological disorders, we can develop a better understanding
of their potential to offer safe and effective alternative treatments.
Potential Therapeutic Applications for Isolinderalactone in Medicine for
the Treatment of Cancers and other Human Complications: An Overview
of Medicinal Importance
Authors: Patel Dinesh Kumar , Patel Kanika
Published: August 2023

Background:

Herbal medicines have been used in both traditional and modern medicine
for the treatment of numerous kinds of human disorders and associated secondary complications.
Lindera species has an important place in traditional medicine and provides a great source of
structurally diverse molecules with important pharmacological potential. Lindera strychnifolia is
used as remedies for the treatment of menstruation complications, frequent urination, and
vomiting. Isolinderalactone is a sesquiterpene class phytochemical isolated from the root extracts
of Lindera aggregate.

Methods:

Biological importance and pharmacological activities of isolinderalactone have been
investigated in the present work through scientific data analysis of different scientific research
work. Scientific data on isolinderalactone have been collected from Google, Google Scholar,
ScienceDirect, PubMed and Scopus using the terms isolinderalactone, Lindera species, and
terpenes and analyzed in the present work in order to know its therapeutic potential in medicine.

Results:

Present work signified the biological importance of isolinderalactone in medicine, which
can modulate several physiological functions in the human body. Isolinderalactone exhibits distinct
anticancer profiles both in vitro and in vivo. Present review data signified the biological importance
of isolinderalactone in medicine, as it exhibits significant potential on human ovarian cancer cells,
glioblastoma, breast cancer, and non-small cell lung cancer. Furthermore, its biological
effectiveness is mainly because of its anti-inflammatory activity, prolyl endopeptidase inhibitory
potential, angiogenic activity, and anti-metastatic effect in medicine. The present study also
summarized the biological significance of Lindera species and sesquiterpenoids in medicine
reported for different pharmacological activities.

Conclusion:

The present work highlighted the biological importance and therapeutic potential of
isolinderalactone in medicine.
Environmental Pollution and Health
Authors: Cocarta Diana Mariana , Velcea A.M.
Published: August 2023

Both developed and developing nations around the world are becoming
increasingly interested in environmental pollution and impact human health. Different
factors contribute to environmental pollution, including an increase in population,
resulting in demand for energy, which causes toxic pollutants that are released into the
air we breathe, on the soil where we grow food, and in the water we drink. These
contaminants may be harmful to both the environment and human health.
The influence of environmental pollution on human health and well-being is discussed
in detail in the current chapter. There are examples of various environmental problems
related to soil, air, and water pollution, as well as evidence of human exposure
pathways and the health effects of different environmental pollutants. Specific
chemical contaminants present in soil, air and water are also evidenced. So, this chapter
introduces the reader to a world where environmental health is synonymous with
human health and where how each of us as individuals treats the environment directly
affects our well-being.
Pengembangan Sistem Kontrol Nutrisi Budidaya Hidroponik Berbasis IoT (Internet of Things) Sawi Samhong (Brassicasinesis L.)
Authors:   Universitas Andalas, Putri Renny Eka , Harahap Hammam Mananda ,   Universitas Andalas, Putri Irriwad ,   Universitas Andalas
Published: August 2023

Sistem hidroponik rakit apung merupakan salah satu sistem yang biasa digunakan dalam hidroponik. Sistem ini menggunakan bak penampung dan menggenangkan tanaman dengan campuran air dan nutrisi. Meskipun banyaknya sistem hidroponik menggunakan rakit apung, tetapi masih kurang dalam pengendalian dan pengontrolan, untuk mengembangkan sistem ini dibutuhkan sistem kontrol penambahan nutrisi AB mix otomatis berbasis Internet Of Things (IoT). Penggunaan sistem IoT dalam hidroponik adalah untuk memudahkan dan memanipulasi hasil panen yang memuaskan dan juga memberikan kemudahan dalam penggunaan hidroponik. Tujuan dari penelitian ini adalah untuk memudahkan Penambahan sistem kontrol dan membuat petani hidroponik lebih mudah untuk mengontrol serta memonitoring nutrisi Ab mix. Sensor yang digunakan untuk mendeteksi nilai ppm dari campuran air dan nutrisi adalah sensor TDS. Sensor TDS membaca nilai ppm pada sistem hidroponik rakit apung. Pembacaan yang diberikan sensor TDS dikirim ke aplikasi blynk dengan bantuan NODEMCU. Sensor membaca data menggunakan rentang nilai ppm. Rentang nilai yang diberikan dari 600-800 ppm. Jika nilai ppm kurang dari 600 ppm maka nutrisi akan bertambah secara otomatis dengan bantuan pompa peristaltik. Nutrisi bertambah sampai dengan rentang nilai ppm yang telah diperintahkan. Data pengamatan dilakukan sekali tiga hari dari jam 08.00 WIB sampai dengan 18.00 WIB. Pada penelitian ini didapatkan perbandingan signifikan antara penggunaan IoT dalam hidroponik. Penggunaan IoT memberikan kemudahan pada hidroponik dalam memenuhi kebutuhan nutrisi apabila nutrisi yang dibutuhkan berkurang.
PENGARUH E-KIE TERHADAP TINGKAT PENGETAHUAN DAN KEPUASAN IBU HAMIL DALAM ANTENATAL CARE DI MASA PANDEMI COVID-19
Authors:   Universitas Brawijaya, Fitria Ruman , Setijowati Nanik ,   Departemen Kedokteran Keluarga, Fakultas Kedokteran, Universitas Brawijaya, Kusumaningtyas Dian ,   Program Studi Sarjana Kebidanan, Fakultas Kedokteran, Universitas Brawijaya
Published: August 2023

Background: The Covid-19 pandemic that has occurred throughout the world affects all aspects, including health aspects. The Covid-19 pandemic is certainly an obstacle for the government to overcome the Maternal Mortality Rate (MMR) and Infant Mortality Rate (IMR) in Indonesia. Optimal Antenatal Care is one of the efforts to suppress MMR and IMR. The government recommends using online counseling to support antenatal care during the Covid-19 pandemic. Research objective: to determine the impact of e-KIE on the knowledge level and satisfaction of pregnant women in antenatal care during the Covid-19 pandemic. Research Methods: The design used was pre-experimental, namely one group pre-post test design to see the effect between the independent variables of the e-KIE method and the dependent variable, namely level of knowledge and satisfaction of pregnant women which were analyzed by marginal homogeneity. The research sample was selected by purposive sampling taken from the registration book (K1) with a population range of pregnant women from September to October 2021 totaling 37 respondents. Research results: there is a significant increase in the level of knowledge of pregnant women before and after e-KIE with a p value of 0.035 and an insignificant effect due to the compatibility between the expected value and the reality of pregnant women with a p value of 0.059. Conclusion: E-KIE significantly affects the level of knowledge of pregnant women and the e-KIE provided does not significantly affect the satisfaction of pregnant women in supporting dialogue/counseling in antenatal care during the Covid-19 pandemic.
Assessing Malaysian Nurses' Knowledge of Blood Transfusion Procedures and Identifying Knowledge Gaps: A cross-sectional study
Authors: Jheffany bin Yazid  , Azliha Minai Rajab  , Suzana binti Yusof  , Angga Wilandika
Published: August 2023

This cross-sectional study aimed to evaluate the knowledge of 316 nurses in a Malaysian public hospital regarding blood transfusion procedures. Convenience sampling was used to select nurses involved in patient care. Data collection employed a validated questionnaire with 33 questions across four sections. Descriptive analysis using SPSS revealed knowledge gaps, particularly in transfusion and adverse reaction management. Findings showed 56.3% with good knowledge, 42.7% with moderate knowledge, and 0.9% with insufficient knowledge. The study emphasizes the importance of targeted education and continuous training to enhance nurses' transfusion-related knowledge and ensure safe practices. Limitations include scope and self-reported data.
EFL Students’ Perspectives and Challenges in Critical Reading Skills for Postgraduate Study
Authors: Shamida Arieff , Sidhu Gurnam Kaur , Kamil Samsul , Du Ruofei
Published: August 2023

Research reveals that EFL postgraduates from China possess limited academic literacy, especially critical reading skills. Therefore, the aim of this study was to investigate EFL students’ perspectives and challenges in critical reading skills for postgraduate study. This study was conducted in a private university located in Peninsular Malaysia involving an intact group of 50 first-year postgraduate students from China. Data were collected through questionnaire and semi-structured interviews. Quantitative findings revealed that EFL students held above-average perceptions of their ability in critical reading, but interview sessions revealed otherwise, as a majority claimed they struggled in employing critical reading skills.
COVID-19 – czas na wnioski Istniejące budynki a możliwość izolowania ludzi
Authors: Wieczorek Anna
Published: August 2023

Celem artykuł jest zwrócenie uwagi decydentom, że istniejące w Polsce budynki nie są przystosowane do izolowania od siebie ludzi, zalecanego w stanie epidemii COVID-19. Dotyczy to nie tylko budynków, w których się mieszka czy pracuje, ale i obiektów służby zdrowia. Słowa kluczowe: epidemia COVID-19, izolacja, kwarantanna, choroba zakaźna
Digital Phenotyping: Data-Driven Psychiatry to Redefine Mental Health
Authors: Oudin Antoine , Maatoug Redwan , Bourla Alexis , Ferreri Florian , Bonnot Olivier , Millet Bruno , Schoeller Félix , Mouchabac Stéphane , Adrien Vladimir
Published: August 2023

The term “digital phenotype” refers to the digital footprint left by patient-environment interactions. It has potential for both research and clinical applications but challenges our conception of health care by opposing 2 distinct approaches to medicine: one centered on illness with the aim of classifying and curing disease, and the other centered on patients, their personal distress, and their lived experiences. In the context of mental health and psychiatry, the potential benefits of digital phenotyping include creating new avenues for treatment and enabling patients to take control of their own well-being. However, this comes at the cost of sacrificing the fundamental human element of psychotherapy, which is crucial to addressing patients’ distress. In this viewpoint paper, we discuss the advances rendered possible by digital phenotyping and highlight the risk that this technology may pose by partially excluding health care professionals from the diagnosis and therapeutic process, thereby foregoing an essential dimension of care. We conclude by setting out concrete recommendations on how to improve current digital phenotyping technology so that it can be harnessed to redefine mental health by empowering patients without alienating them.
Development of a Core Set of Quality Criteria for Virtual Reality Applications Designed for Older Adults: Multistep Qualitative Study
Authors: Napetschnig Alina , Brixius Klara , Deiters Wolfgang
Published: August 2023

Background

Virtual reality (VR) applications are gaining growing significance, particularly among older adults. These applications can provide valuable support to older adults by offering immersive VR content that positively influences various aspects of their daily lives, including activities of daily living. Furthermore, VR applications can contribute to the enhancement of cognitive and motor skills, ultimately leading to an improved quality of life for older individuals. Nevertheless, to ensure a positive impact, it is crucial to develop VR experiences that are tailored to the needs and preferences of the users.

Objective

This study aims to develop a core set of quality criteria and guidelines for the development of user-centered VR applications specifically designed for older adults (target group).

Methods

The multistep qualitative study design comprised several key stages, beginning with a systematic literature search. This was followed by a framework analysis aimed at identifying a core set of criteria. Subsequently, these criteria underwent validation through expert workshops. The outcomes achieved through this iterative process were organized and categorized into criteria, accompanied by explanations detailing the underlying categories or codes.

Results

The quality criteria core set for older adults–friendly VR applications has been developed through an iterative process. It is divided into 2 distinct parts, each containing criteria categorized into specific areas. The first part includes the following categories: (1) quality assurance of medical/health content, (2) data protection provisions, (3) quality requirements, (4) consumer protection, and (5) interoperability. The second part includes the following categories: (1) graphic/quality, (2) 3D character/avatar, (3) providing in-game instructions and prompts, (4) interaction, (5) navigation, and (6) promotion of user motivation and loyalty to use. The results imply a differentiated scope as well as a differentiated granularity of the criteria.

Conclusions

Considering the ongoing advancement of VR technology and the diverse needs within the older adult demographic, it is essential to assess the quality criteria core set results on an individual basis.