bluuebunny/crossref_metadata_2025 huggingface dataset:
The Omeprazole Story: How Endurance in Research May Pay Off
Authors: Carlsson Enar
Published: February 2025

Based on the dictum: No acid – no ulcer a number of pharmaceutical companies started up research aiming at a drug, inhibiting gastric acid secretion during 1960s. The focus of that research was gastrin, the gastric acid stimulating hormone released from G-cells in the antral part of the stomach. The Searle company in the US tried to find a small molecule inhibiting the gastrin receptor, while AstraHässle in Sweden tried to find something that decreased the release of gastrin from the G-cells. SK&F focused on the H2-receptor also involved in the regulation of gastric acid secretion. The SK&F approach lead to the first clinically useful acid inhibitor, cimetidine. The AstraHässle approach was a dead end, as was the Searle approach. However, the Searle idea led to the discovery of CMN 131, a compound which had some acid inhibitory effect, but was also toxic. When AstraHässle failed with their first attemptthey picked up on CMN 131 as a new lead around 1972. This approach resulted in timoprazole (1974), picoprazole (1977), and eventually omeprazole (1979). Omeprazole was first launched in Sweden 1988, under the trade name Losec. In 1997 Losec reached a yearly sale of more that 6 billion USD and became the world's biggest drug.
Drug Design with ADME in Mind: Recent Paradigm Shifts in Drug Discovery
Authors: Borchardt Ronald T.
Published: February 2025

In an attempt to reduce the attrition rate of new chemical entities (NCEs) in development, many pharmaceutical companies have implemented a new drug discovery paradigm that involves optimizing the “pharmacological activity” as well as the “drug-like” properties (e.g. solubility, chemical/enzymatic stability, protein binding, cell permeability) during the lead optimization process in drug discovery. Traditionally, optimizing these “drug-like” properties was not considered by discovery scientists to be their responsibility. Instead, discovery scientists felt that undesirable “drug-like” properties of drug candidates would be “fixed” by preclinical development scientists. However, today most discovery scientists recognize that the “drug-like” properties of NCEs are intrinsic properties of the molecules and that it is their responsibility to optimize both the “pharmacological activity” and the “drug-like” properties of these molecules. In this chapter, the rational for this paradigm shift in drug discovery is discussed. In addition, a case history focusing on the optimization of the “drug-like” properties of cyclic prodrugs of an opioid peptide DADLE (H-Tyr-D-Ala-Gly-Phe-D-Leu-OH) is provided.
Global Governance: prospects and challenges
Authors: Thynne Ian  , Massey Andrew
Published: February 2025

This chapter sets the scene for a detailed exploration of the human factor in global governance, both in theory and in practice. While emerging systems or patterns of global governance are open to a variety of interpretations and possible descriptions, two prominent features are singled out in this chapter for particular attention. The first concerns the nature and scope of global governance and what may be described as global public goods. The second is the issue of power and power relationships, which are of immediate significance to the various forms of global collective action. These features constitute the functional and institutional foundations on which the human factor can be addressed. They influence, if not determine, the prospects for global governance in the foreseeable future. They pose challenges for those involved in the sectors and structures within or through which collective action can be fostered and maintained on a global scale. Too often, the existing literature gives scant attention ‘to the actors and mechanisms behind the exercise of power outside the compass of States’. In response to this condition, the calls for democratisation and accountability of global governance need to be linked to a ‘detailed consideration of governance mechanisms’ (Whitman 2002:47), including the extent to which they are appropriately geared to the United Nations Millennium Development Goals (MDGs).
Leadership Capacity Development Perspectives in Africa
Authors: Kauzya John-Mary
Published: February 2025

The major paradigm shift implicit in global governance has introduced the need for reconsideration of the nature of the mechanisms through which the human factor in Africa can be deployed and used to maximise its benefit to Africa and its peoples. For many years already, the region has tried to break free of the vicious circle engendered by absolute poverty, with all that it entails. Breaking this vicious circle calls for pragmatic leaders. This chapter addresses the nature and several dimensions of the leadership required, in the framework of an overall effort to upgrade the human factor and human resources management in public service reform.
Virtual Intensive Care Unit (ICU): Real-Time Simulation Environment Applying Hybrid Approach Using Dynamic Bayesian Networks and ODEs
Authors: Abkai Ciamak  , Hesser Jürgen
Published: February 2025

Combining deterministic (e.g. differential equations) and probabilistic (Bayesian Networks) approaches to model physiological processes in a real-time software environment leads to a novel model for simulation of human patient physiology especially relevant for intensive care units (ICU). Using dedicated HW/SW interfaces simulated patient signals are measurable with standard monitoring systems. Therefore, this system, based on realistic simulations, is very well suited for teaching and education. Additionally, the environment is usable for inferring patient-specific model structures and parameters. We introduce a hierarchical modeling approach, which allows building complex models based on aggregation of simple sub models. The simulation is controlled to run in real-time with typical sampling times of 1–10 ms (depending on model complexity) on a standard PC (Pentium 2.66 GHz CPU).
Virtual Pelvic Anatomy and Surgery Simulator: An Innovative Tool for Teaching Pelvic Surgical Anatomy
Authors: Holubar Stefan D.  , Hassinger James P.  , Dozois Eric J.  , Camp Jon C.  , Farley David R.  , Fidler Jeff L.  , Pawlina Wojciech  , Robb Richard A.
Published: February 2025

Pelvic three-dimensional (3-D) anatomy is complex and can be difficult to visualize. We have developed an alpha-version virtual anatomic model that will facilitate a) student learning of anatomy b) resident preparedness for operation, c) surgical planning for complex, multidisciplinary procedures. This educational module is composed of the virtual anorectum, an anatomically accurate, interactive model of the anorectum and pelvic viscera based on co-registered human computed tomographic (CT) and magnetic resonance (MR) images. It also consists of a physical model fabricated from the same data-set using stereolithography. Usability and functionality was assessed in a sample of surgical trainees. Feedback demonstrated that the module is an efficient adjunct to medical education and surgical planning. Ultimately, we envision a deformable virtual model that allows residents and surgeons to rehearse complex surgical procedures by performing virtual surgery, thereby improving preparedness for real operations. Such a model will be integrated into a colorectal surgery educational curriculum, and in the future may represent a unique method of competency testing.
V-Scope: Design and Implementation of an Immersive and Desktop Virtual Reality Volume Visualization System
Authors: Koning Anton H.J.  , Rousian Melek  , Verwoerd-Dikkeboom Christine M.  , Goedknegt Lennard  , Steegers Eric A.P.  , van der Spek Peter J.
Published: February 2025

In this paper we present a new implementation of the virtual reality workstation concept. Based on an application originally developed for immersive virtual environments such as CAVEs, V-Scope allows clinicians and researchers to investigate their three dimensional (3D) imaging data with truly 3D views and interactions. This greatly improves the understanding of the data, and allows the efficient measurement of volumes and distances in a way that was previously not possible.
Robotic Assisted Reduction of Femoral Shaft Fractures using Stewart Platform
Authors: Majidifakhr Kamran  , Kazemirad Siavash  , Farahmand Farzam
Published: February 2025

A robotic system with 6 DOF mobility was proposed for reduction of femoral shaft fractures based on Stewart platform. A plan for implementing the platform on bone fragments was introduced and a step by step strategy for performing the reduction procedure, based on the system's inverse kinematic solution, was proposed. The efficacy of the system was evaluated in some case studies and it was shown that it can be locked to act as an external fixator.
Integrating Cognitive Simulation into the Maryland Virtual Patient
Authors: Nirenburg Sergei  , McShane Marjorie  , Beale Stephen  , Jarrell Bruce  , Fantry George
Published: February 2025

This paper briefly describes four cognitively-related aspects of modeling a virtual patient: interoception, decision-making, natural language processing and learning. These phenomena are treated within the Maryland Virtual Patient simulation and training environment.
A Virtual Human Agent for Assessing Bias in Novice Therapists
Authors: Parsons Thomas D.  , Kenny Patrick  , Cosand Louise  , Iyer Arvind  , Courtney Chris  , Rizzo Albert A.
Published: February 2025

Monitoring the psychological and physiological activity of persons interacting with virtual humans poses exacting measurement challenges. Three experiments are reported in this paper. In these experiments we made use of Virtual Human Agent technology to assess persons' psychological and physiological responses to Virtual Standardized Patients. The first experiment provided support for the usability of the Virtual Standardized Patients through the use of a virtual character emulating an adolescent male with conduct disorder. In the second experiment we further developed the technology and aimed at assessing whether novice mental health clinicians could conduct an interview with a virtual character that emulates an adolescent female who has recently been physically traumatized. The third experiment looked at the usability of Virtual Standardized Patients for eliciting psychophysiological responses following exposure to virtual humans representing different ethnicities.
Plug-and-Play Tool Handles for Laparoscopic Surgery Simulators
Authors: Banihani Suleiman  , Dutkin Max  , Ali Syed  , Arikatla Venkata Sreekanth  , Sankaranarayanan Ganesh  , De Suvranu
Published: February 2025

With ever growing attention of medical community on the usage of surgical simulators as effective training means, development of robust and cost-effective haptic tool interfaces is very much necessary. We have developed such tool interfaces that can be easily plugged to PHANTOM® Omni™. Besides simulating actual tools in operating room, they are cost-effective and are easy to build.
Novel Device DeeDee for Neuromotor Control with Augmented Reality and Multiparametric Sensors Fusion
Authors: Rovetta Alberto
Published: February 2025

This paper deals with a new device for neuromotor control analysis, which is used for sport performances, neurodegenerative diseases, stress detection and alcohol and drugs detection with Police checks.
Quantification of Intraocular Surgery Motions with an Electromagnetic Tracking System
Authors: Son Ji  , Bourges Jean-Louis  , Culjat Martin O.  , Nistor Vasile  , Dutson Erik P.  , Carman Gregory P.  , Hubschman Jean Pierre
Published: February 2025

Motion tracking was performed during a combined phacoemulsification (PKE) and pars plana vitrectomy (PPV) procedure on a pig eyeball. The UCLA Laparoscopic Training System (UCLA-LTS), which consists of electromagnetic sensors attached to the surgical tools to measure three-dimensional spatial vectors, was modified to enable quantification of intraocular surgery motions. The range of motion and time taken to complete the given task were successfully recorded.
Tele-Control of an Endoscopic Surgical Robot System between Japan and Thailand for Tele-NOTES
Authors: Suzuki Naoki  , Hattori Asaki  , Ieiri Satoshi  , Konishi Kozo  , Maeda Takashi  , Fujino Yuichi  , Ueda Yukihiro  , Navicharern Patpong  , Tanoue Kazuo  , Hashizume Makoto
Published: February 2025

We describe our experience of the development of a endoscopic surgical robot system that can penetrate into the body through the esophagus and perform surgeries in the upper gastric tubes and several organs in the abdominal cavity. In this paper, we describe the results of an experiment using this robot. We describe the configuration of the control system using a gigabit ethernet system named JGN2 for the endoscopic surgical robot. We also describe the results of the first telesurgery experiment using the NOTES (natural orifice transluminal endoscopic surgery) procedure (tele-NOTES), performed at a distance of about 3,750 km.
Haptic Simulation of the Liver with Respiratory Motion
Authors: Villard Pierre-Frédéric  , Jacob Mathieu  , Gould Derek  , Bello Fernando
Published: February 2025

During a standard procedure of liver biopsy, the motion due to respiration may be difficult to handle. The patient is often requested to hold his breath or to breathe shallowly. Ideally, this physiological behaviour should be taken into account in a virtual reality biopsy simulator. This paper presents a framework that accurately simulates respiratory motion, allowing for the fine tuning of relevant parameters in order to produce a patient-specific breathing pattern that can then be incorporated into a simulation with real-rime haptic interaction. This work has been done as part of the CRaIVE collaboration [1], which aims to build interventional radiology simulators.
Characterization of Anisotropy in Viscoelastic Properties of Intra-abdominal Soft Tissues
Authors: Deo Dhanannjay  , Singh Tejinder Paul  , Dunnican Ward  , De Suvranu
Published: February 2025

A portable instrumentation rig is presented for characterizing nonlinear viscoelastic anisotropic response of intra-abdominal organ-tissues. Two linearly independent in-situ experiments are performed at each indentation site on the intra-abdominal organ, by subjecting the organ to 1) normal and 2) tangential displacement stimuli using the above robotic device. For normal indentation experiments, the indenter is ramped into the tissue and held for 10 seconds before sinusoidal indentation stimuli are applied. For tangential (shear) loading, the indenter tip is rigidly glued to the soft tissue surface. Sinusoidal displacement stimuli are then applied laterally in the tangential plane and the force response is recorded. Tangential loading is repeated along orthogonal directions to measure in-plane mechanical properties. Combined analysis of both experiments leads to assessment of anisotropy. In situ experiments on fresh human cadavers are currently under way at the Albany Medical College.
Rethinking Fidelity, Cognition and Strategy: Medical Simulation as Gaming Narratives
Authors: Ellaway Rachel H.  , Topps David
Published: February 2025

Simulations can transcend the literal representation of practice worlds. This paper considers the use of gaming and narrative to identify key underlying features and the ways in which they can be used in creating simulation activities.
Failure of Electronic Medical Records in Canada: A Failure of Policy or a Failure of Technology?
Authors: Keshavjee Karim  , Manji Anil  , Singh Baljit  , Pairaudeau Nick
Published: February 2025

This paper utilizes three frameworks described in the literature to better understand the reasons why Canada lags other OECD countries in EMR implementation. First, we use an EMR policy framework to evaluate three provincial EMR implementation programs across Canada. Second, we use an EMR implementation multi-theoretical framework that is predictive of EMR success to evaluate those same programs. Finally, we use a cost-benefit framework developed in the USA to compare the cost-benefits of EMR implementations in Canada compared to those in the USA. We draw conclusions and make recommendations based on our findings.
Where is Nursing in the Electronic Health Care Record?
Authors: Mitchell Beverly  , Petrovskaya Olga  , McIntyre Marjorie  , Frisch Noreen
Published: February 2025

The authors explore the possibilities for documenting professional nursing practice in an electronic health record. Recognizing that there are a variety of approaches to electronic documentation, the intent of this discussion is to generate a general rather than a particular approach to this issue. Nurses themselves must determine the ways in which professional nursing care will be captured in the electronic systems used in their facilities. Questions that arise from nursing include: How can nurses balance generalized care and protocol management with the need for documentation of each individual's nursing needs and particular experiences? How can the goals of nursing care be incorporated into the record? How can nursing actions/interventions be clearly communicated to all members of the health care team? In what ways can an electronic record document collaboration with the client to determine individualized outcomes of care and treatment? In considering these questions a number of issues arise: the selection of standardized languages to be used in the records, the title of the record, the tension between coding and text, the accessibility and transferability of the record, the ability to retrieve data on nursing outcomes through data mining techniques, ownership of the record, and privacy/security of the information stored. Although the paper will make no attempt to answer these questions it will draw on relevant journal articles to provide a context for this pivotal change in that way we account for health care practice.
Patient Self-management and Chronic Illness: Evaluating Outcomes and Impacts of Information Technology
Authors: Cummings Elizabeth  , Turner Paul
Published: February 2025

Chronic illness is increasing in Australia and throughout the world. It is proving to be a large burden upon health systems. In response, a number of approaches are being tried including the introduction of self-management programmes to assist people in improving their health outcomes. There are also claims that the introduction of information and communications technology (ICT) tools can improve the management of these chronic conditions.
Architectural and Usability Considerations in the Development of a Web 2.0-based EHR
Authors: Senathirajah Yalini  , Bakken Suzanne
Published: February 2025

In our previous work, we described an electronic health record (EHR) architecture based on Web 2.0 principles. With this architecture, users in healthcare and public health can select, configure, share and control the information and interfaces they use by means of simple techniques such as “drag-and-drop” without the intervention of programmers. We extend this work by discussing architectural and usability considerations important for creating such an EHR. These include: new affordances facilitating element creation, responsiveness while using rich client-side interaction, consistency versus flexibility, security, workflow and evaluation.
Modeling Knowledge Resource Selection in Expert Librarian Search
Authors: Kaufman David R.  , Mehryar Maryam  , Chase Herbert  , Hung Peter  , Chilov Marina  , Johnson Stephen B.  , Mendonca Eneida
Published: February 2025

Providing knowledge at the point of care offers the possibility for reducing error and improving patient outcomes. However, the vast majority of the physician's information needs are not met in a timely fashion. The research presented in this paper characterizes an expert librarian's search strategies as it pertains to the selection and use of various electronic information resources. The 10 searches conducted by the librarian to address the physician's information needs varied in terms of complexity and question type. The librarian employed a total of 10 resources and used as many as 7 in a single search. The longer term objective is to model the sequential process in sufficient detail as to be able to contribute to the development of intelligent automated search agents.
“Physicians' Adoption Score” – Physicians are not a Homogenous Group
Authors: Sajedi Mitra  , Kushniruk Andre W.
Published: February 2025

The issue of “Physicians' Adoption” is one of the big challenges facing wide-scale implementation of electronic health records (EHRs). An important question is why the number of physicians using EHRs in their practice has not reached the level expected. While this issue has been addressed widely in the literature, the term “physicians” is used generally to encompass a broad range of roles and responsibilities. Physicians are not a homogeneous group and, without a good understanding of the differences among physicians, it is not logical or feasible to come up with a universal blue print devised to convince all physicians to accept an EHR implementation in their practices. First we discuss the barriers to implementing an EHR based on the characteristics of different types of physicians and then introduce an “Adoption Score” for physicians and provide a tool to measure the barriers. We discuss the importance of this scoring system and how similar methods can be helpful to assign an adoption score at an organizational level.
Use of Case Mix Tools for Utilization Management and Planning
Authors: Perry Sheril  , Homan Craig
Published: February 2025

An aging population, new technologies and drugs, and tightening constraints on financial and human resources have placed increased demands on hospitals to meet health care needs. Canadian hospitals, health regions, and ministries are placing a high priority on the evaluation of appropriateness and efficiency of medical care and on the proactive and targeted reduction of inefficiencies. The CMG+ grouping methodology is a case mix tool produced by the Canadian Institute for Health Information (CIHI) to analyze the acute-care inpatient population in Canada. CMG+ methodology can be applied, for example, to utilization management. The expected length of stay (ELOS) indicator can be used as a benchmark for assessing the length-of-stay distribution of various subgroups of patient activity. It can also be used to compute potentially conservable days and to identify those patient subgroups where gains in efficiency may be realized. We describe CMG+ utilization management using this and other examples.
Clinical Support in Primary and Ambulatory Care: Canadian Lessons to be Learned from the UK Patient Summary Care Record (SCR) Initiative
Authors: Sutton Chris  , Malovec Shannon
Published: February 2025

There is an increasing requirement for interdisciplinary teams to share patient data to ensure optimal care. Healthcare providers in all settings from Emergency Medicine to long-term care management need access to patient information. In the UK, developments to address the need for information sharing have uncovered issues that the Canadian eHealth establishment would do well to heed when undertaking its own initiatives.
Geometry of verticaloblique image combinations
Authors: Jacobsen K.
Published: February 2025

For city planning and security services the combination of vertical and oblique images like from Pictometry and Multivision recently became very popular. For larger cities a high number of such image combinations are even included in Microsoft Virtual Earth. The geo-reference of the image combinations usually is based on direct sensor orientation – the combination of GPS and inertial measurement units. The images are taken by camera systems like Track'Air MIDAS, equipped with 5 Canon EOS cameras, each with 4992×3328 pixels. The Canon EOS is not really a metric camera; it keeps the inner and the system orientation only stable during one photo flight. The images are also used for simple measurement purposes as well as the generation of 3D-city models. If object information without disturbing loss of accuracy against the direct sensor orientation is required, a system calibration during the day of the photo flight has to be done. The method of calibration and achieved accuracy is described as well as the characteristics and potential of the image combinations.
Landuse changes of Goleniow Forest in 1973–2000 using remote sensing methods
Authors: Kunz M.  , Klimecki M.
Published: February 2025

The Goleniow Forest is a very interesting, compact compact forest complex situated on the eastern coasts of the Szczecinska Bay and Dabie Lake (north-western part of Poland). The study area administratively belongs to Zachodniopomorskie Voivodeship and it is managed by the Goleniow Forest Inspectorate. It covers the area of 53 989 ha, within it over 22 300 ha are forests, mainly pine-trees. Recently, in the study area, there have been clear anthropogenic changes mainly connected with the development of wood industry. There are intensive cuttings in the area of the Forest Inspectorate. 83 500 m2of wood are cut every year. Clearings are reforested together with non-forest areas. Because of good natural conditions, 4 natural reserves have been created in the area of the Inspectorate, and further 4 are being worked out. The analyzed region is included in the national ecological net ECONET-POLAND as an international junction area, and within it the area of habitat preservation has been created in the scheme of NATURA 2000. The aim of the study was to find out the direction and dynamics of changes in a landuse in the area of the Goleniow Forest in 1975–2000 with the application of accessible satellite imageries LANDSAT and general maps of treestands. Satellite imageries from 1975 and 2000, general maps of treestands from 1973, 1985 and 1997, and topographic maps were used for the analysis. The study was done with the technology of geographic information system.
Future Internet Socio-Economics – Challenges and Perspectives
Authors: Hausheer David  , Nikander Pekka  , Fogliati Vincenzo  , Wünstel Klaus  , Callejo María Ángeles  , Jorba Santiago Ristol  , Spirou Spiros  , Ladid Latif  , Kleinwächter Wolfgang  , Stiller Burkhard  , Behrmann Malte  , Boniface Mike  , Courcoubetis Costas  , Li Man-Sze
Published: February 2025

Socio-economics aims to understand the interplay between the society, economy, markets, institutions, self-interest, and moral commitments. It is a multidisciplinary field using methods from economics, psychology, sociology, history, and even anthropology. Socio-economics of networks have been studied for over 30 years, but mostly in the context of social networks instead of the underlying communication networks. The aim of this paper is to present and discuss challenges and perspectives related to “socio-economic” issues in the Future Internet. It is hoped that this will lead to new insights on how to structure the architecture and services in the Internet of the future.
Feature Diagrams for Change-Oriented Programming
Authors: Ebraert Peter  , Classen Andreas  , Heymans Patrick  , D'Hondt Theo
Published: February 2025

The idea of feature-oriented programming is to map requirements to features, concepts that can be composed to form a software product. Change-oriented programming (ChOP), in which features are seen as sets of changes that can be applied to a base program, has recently been proposed as an approach to FOP. Changes are recorded as the programmer works and can encapsulate any developer action, including the removing of code.
Interactive Highly Realistic Virtual Reality as a Tool for Understanding the Genesis and Treatment of Psychotic Symptoms
Authors: Zányi Eva  , Selmanovic Elmedin  , Broome Matthew  , Czanner Silvester  , Birchwood Max  , Chalmers Alan  , Singh Swaran
Published: February 2025

Schizophrenia can be a devastating lifelong psychotic disorder with a poor prognosis. National guidelines in the UK recommend the provision of cognitive behavioral therapy (CBT) to all those suffering with psychotic disorders, but there is a lack of trained therapists in the UK able to provide such a treatment. Developing high quality automated technologies that can serve as an adjunct to conventional CBT should enhance the provision of this therapy, and increase the efficiency of the therapists in practice. The latter will occur by enabling alternate professionals to aid in the delivery of therapy, to enable behavioral experiments to be conducted in the clinic, and for sessions to be recorded and re-played such that the patient can deliver therapy to him or herself. As such the system will enable patients to become experts in, and providers of, their own treatment and decrease the number of sessions needed to be led by a trained CBT therapist. A key feature of any such system is the level of realism required to ensure a compelling session in which the user is not adversely affected by the system itself. This paper presents a high-fidelity virtual environment to help better understand the environmental triggers for psychosis.
A Comparison of Different Survey Periods in Online Surveys of Persons with Eating Disorders and Their Relatives
Authors: Wesemann Dorette  , Grunwald Martin
Published: February 2025

Evaluations of Internet-based interventions offered to patients with mental or psychosomatic illnesses are mostly carried out in the form of online surveys. Up until now, the methods used in carrying out these evaluations have seldom been systematically investigated. This study tested whether modifying this time interval brings about changes in the respondents' response behavior and the make-up of the sample. Two survey strategies were compared: a post-block survey (with a variable time interval between the Internet-based intervention and the online survey) and a post-spot survey (time interval standardised to 90 days). In the post-spot survey it was possible to prove a higher response rate (39.9%) than in the post-block survey (28.0%) as well as a higher number of questionnaires completed correctly and in full. No differences were identified in the basic characteristics of the random samples. It was possible to demonstrate that the quality of the online survey could be improved by standardising the length of time. Standardisation of the time difference implies a controllable degree of influence on the quality of the evaluations.
Playmancer Project: A Serious Videogame as an Additional Therapy Tool for Eating and Impulse Control Disorders
Authors: Jiménez-Murcia Susana  , Fernández-Aranda Fernando  , Kalapanidas Elias  , Konstantas Dimitri  , Ganchev Todor  , Kocsis Otilia  , Lam Tony  , Santamaría Juan J.  , Raguin Thierry  , Breiteneder Christian  , Kaufmann Hannes  , Davarakis Costas
Published: February 2025

Reviews and few non-controlled studies showed the effectiveness of several specific designed computer video-games as an additional form of treatment in several areas. However, there is a lack in the literature of specially designed serious-games for treating mental disorders. Playmancer (ICT European initiative) aims to develop and assess a serious videogame that may help to treat underlying processes (e.g. lack of self-control strategies) in Eating and Impulse control disorders. Preliminary data will be shown.
Assessment of Inhibition Deficits with the Virtual Classroom in Children with Traumatic Brain Injury: A Pilot-Study
Authors: Nolin Pierre  , Martin Cyndie  , Bouchard Stephane
Published: February 2025

This study compared the performance of 8 children who have sustained a traumatic brain injury on the traditional VIGIL Continuous Performance Test and the Continuous Performance Test included in the Virtual Classroom. Results supported the hypothesis, showing that the Continuous Performance Test from the Virtual Classroom showed more sensitivity concerning inhibition deficits. More precisely, children showed more commission errors and longer reaction time. These results can be explained by the ecological character of the Virtual Classroom, meaning that this instrument is close to real-life experiences and requires more attention and inhibition resources.
A Free Tool for Motor Rehabilitation: NeuroVR 1.5 with CamSpace
Authors: Algeri Davide  , Carelli Laura  , Gaggioli Andrea  , Riva Giuseppe
Published: February 2025

NeuroVR 1.5 is a cost-free virtual reality platform based on open-source components, allowing professionals to easily modify a virtual world, to best suit the needs of the clinical setting. The goal of the present project is to extend the functionalities of this platform by allowing users to interact with the virtual environment by using gestures detected by a webcam. To this end, we used CamSpace Beta 7, a cost-free and user-friendly computer vision technology. We describe how this integrated approach can be used to implement cognitive and motor training programs, involving partial or full-body movements.
The Introduction of Nanotechnology As a Societal Experiment
Authors: van de Poel Ibo
Published: February 2025

Risks and hazards of most new nanotechnologies cannot be completely predicted in the laboratory. Therefore the introduction of such nanotechnologies into society amounts to a societal experiment. I propose four conditions under which such societal experiments with nanotechnology are acceptable (absence of alternative testing methods, controllability, proportionality of hazards to benefits and informed consent). In addition, four conditions for the responsible set-up of such experiments are proposed (monitoring, feedback, conscious scaling-up, containment of hazards).
Cancer Patients' Questions and Concerns Expressed in an Online Nurse-delivered Mail Service: Preliminary Results
Authors: Andersen Trine  , Ruland Cornelia M.
Published: February 2025

Internet-based online patient-nurse communication (OPNC) services can constitute an important opportunity to support patients to manage their illness between treatment and rehabilitation while being at home. We explored the content of messages sent by prostate and breast cancer patients to an OPNC service to identify symptoms, problems, concerns and information needs expressed in these messages. Using qualitative content analyses we examined 276 messages sent from 38 breast and 22 prostate cancer patients during 15 months. Two main themes emerged: Concerns about physical symptoms and treatment side effects; and worries and questions about treatment and follow up. Analyses showed that cancer patients have many serious unanswered questions and concerns that can create considerable uncertainty and anxiety. An OPNC service can to a great extent meet patients' need for advice and information and thus be an important health care supplement that can improve quality of care.
The Elderly Demographic Time Bomb – Sharing the Load with the Active Ageing: Can eHealth Technologies Help Defuse it?
Authors: Layzell Brian  , Manning Bryan  , Benton Stephen
Published: February 2025

This paper examines strategic health management and practical health service delivery issues inherent in the potential doubling in the number of over 65s over the next two decades. It considers the use of scarce and overloaded resources in providing care and support to this age group across the spectrum of community environments, and advocates the use of shared information services coupled with the deployment of ‘smart’ technologies to supplement available yet scarce professional resources as well as enabling elderly people to maintain a safe, active and independent lifestyle. An innovative approach to provide support both to an active ageing population, as well as the more frail or vulnerable members of society, is outlined. Based on an ongoing research programme, this centres on the extension of the Smart Home concept to create an overarching smart environment. This combines advanced information, communications and textile technologies with physiological monitoring and location based processes and services, to protect and support users by maintaining the range of services they need. Discussion of the behavioural dynamics inherent in organizational change concludes the paper.
The Evaluation of Using Road-Map Guided Excel VBA Training to Promote Nursing Informatics in Taiwan
Authors: Hou I-Ching  , Liu Che-Wei  , Hsu Chiao-Ling  , Chang Polun
Published: February 2025

In Taiwan nursing informatics is taking off. It is therefore strategically important to educate our nurses what nursing informatics is in a short time. We used a method of road-map guided Excel VBA to educate our nurses how to cope with their informatics needs. An eight-day training program based on this concept was implemented in the one regional hospital and a survey was done at the end of the program to evaluate the participants' perception of the training program. The results show very high acceptance and positive outcomes. We suggest that the method of road-map guided Excel VBA might be a promising strategy to promote nursing informatics internationally Taiwan.
Sending Electronic Nursing Discharge Messages Using the HL7 v3 Care Provision Standard
Authors: Goossen William
Published: February 2025

There is a growing need to exchange nursing related information electronically from one health care professional to another, crossing institutional, time and language boarders. Both continuity of care, care for populations, decision support and secondary use of patient data are valid uses of nursing information. Achieving electronic exchange of nursing information requires information analysis, modeling, standardization and deployment in electronic health systems. The HL7 working group ‘Patient Care’ has developed a set of HL7 v3 messages that allows nursing content to be specified and exchanged between electronic patient record systems, or systems deployed for secondary data use. This contribution discusses the dynamics of the process and the use of electronic messages for continuity of care. Also, the use of nursing terminology and assessment scales within HL7 v3 messages is illustrated. The Care Provision message is useful for sending structured nursing information between health care facilities.
Models, Standards and Structures of Nursing Documentation in European Countries
Authors: Thoroddsen Asta  , Saranto Kaija  , Ehrenberg Anna  , Sermeus Walter
Published: February 2025

The use of standardized nursing languages varies between and even within different European countries. Standardization of a nursing language is a demanding process which requires substantial methodological and technological knowledge as well as cultural experience in terminology development work. A survey was carried out to describe the current state of art of the use of models, standards and structures in nursing documentation. A web-based questionnaire was targeted to members of the Association for Common European Nursing Diagnoses, Interventions and Outcomes (ACENDIO). Replies were received from 17 countries in Europe. Results show that the nursing process is the model most often used to structure nursing documentation in Europe. Many standardized nursing terminologies are used in Europe but general use in nursing is still lacking which makes access to nursing data an obstacle. In more than 60% of the institutions in the countries that replied were nursing data not stored and could therefore not be retrieved. These results should be a major concern to nurses in Europe. This relates to the lack of use of standards in use of nursing terminologies and information systems. Standardization activities in existing and evolving networks in Europe, as well as in other parts of the world, need to be enhanced. As a European platform, ACENDIO can play a role in these standardization activities and should develop its role accordingly.
Individualizing Cancer Care with Interoperable Information Systems
Authors: McCormick Kathleen A.
Published: February 2025

There are three levels of interoperable informatics that are co-occurring in the United States to link data to provide more comprehensive care to patients. One is the National Health Information Network (NHIN) that is establishing use case scenarios and standards for interoperability for patients with multiple conditions. The second is the National Cancer Institute's project that supports the enterprise work called the Cancer Bioinformatics Grid (caBIG®) in linking clinical care with bioinformatics, tissue repositories, and imaging for patients with cancer. The third is in the area of translating the discoveries of biology to bedside care through the National Institutes of Health (NIH) translational research efforts to get these new biomedical and genomic discoveries in practice in multiple healthcare delivery environments. These developments are becoming global networks in the diagnosis and cure of cancer as the primary outcome. This paper describes the national efforts and the global connection to Europe through the caBIG® program. The European program that is beginning to link to cancer research internationally is the National Cancer Research Institute (NCRI) in the United Kingdom. They are developing the NCRI Oncology Information Exchange (ONIX) to provide the cancer research community with the ability to share information.
Framework for Preventing Accidental Falls in Hospitals – Management Plan for ADL, Medication and Medical Conditions
Authors: Kato Shogo  , Tsuru Satoko  , Iizuka Yoshinori
Published: February 2025

Prevention and reduction of medical accidents is essential. Among medical accidents, accidental falls remain a serious problem. While “assessment score sheets” have already been used in hospitals to prevent accidental falls, satisfactory results have not actually been achieved. In this study, we aim to establish a methodology for preventing accidental falls. We consider that the ‘management plan’ for each patient includes three factors. A plan of instructions for patients on actions they can take for safety in their ADL (Activities of Daily Living) is essential as a base. Second, a plan to keep up with any short term change in a patient's state is needed, because the state of a hospitalized patient will usually be temporarily affected by medication and changing medical conditions. We develop a model for preventing accidental falls, which enable us to design appropriate management plan for each patient. Then, we develop a prototype system based on the designed model. Finally, we address the result of verification of the model, by applying the prototype system into actual cases in hospitals.
The Emerging Role of Educational Informatics
Authors: Weiner Elizabeth E.  , Trangenstein Patricia A.
Published: February 2025

Initial growth in the field of nursing informatics has centered primarily on the clinical setting. Much has been written about the systems developed and evaluated and possible new roles that one can play in the clinical environment. The educational arena has not fared as well. Early attention has been focused on the integration of educational technology or on competency-based skills in informatics according to program levels of students. This paper will focus on the emerging role of educational informatics. Examples will provide nurses with a better understanding of the roles played by the educational informaticist in crafting the science of nursing informatics to produce better nursing education outcomes.
Validation of the Impact of Health Information Technology (I-HIT) Scale: An International Collaborative
Authors: Dykes Patricia C.  , Hurley Ann C.  , Brown Suzanne  , Carr Robyn  , Cashen Margaret  , Collins Rita  , Cook Robyn  , Currie Leanne  , Docherty Charles  , Ensio Anneli  , Foster Joanne  , Hardiker Nicholas R.  , Honey Michelle L.L.  , Killalea Rosaleen  , Murphy Judy  , Saranto Kaija  , Sensmeier Joyce  , Weaver Charlotte
Published: February 2025

In 2005, the Healthcare Information Management Systems Society (HIMSS) Nursing Informatics Community developed a survey to measure the impact of health information technology (HIT), the I-HIT Scale, on the role of nurses and interdisciplinary communication in hospital settings. In 2007, nursing informatics colleagues from Australia, England, Finland, Ireland, New Zealand, Scotland and the United States formed a research collaborative to validate the I-HIT across countries. All teams have completed construct and face validation in their countries. Five out of six teams have initiated reliability testing by practicing nurses. This paper reports the international collaborative's validation of the I-HIT Scale completed to date.
Creating a Governmental Policy Framework for Adoption of an Electronic Health Record
Authors: Mills Mary Etta C.  , Newbold Susan K.
Published: February 2025

Promotion and support of electronic health records and electronic information exchange through governmental policy development requires a framework that considers cost, benefits, barriers, risks and policies at the statewide level that might accelerate or retard adoption. Recommendations to underpin governmental policy involve financial incentives, technology adoption, legal and regulatory considerations and consumer education.
A Leadership Initiative to Improve Paraprofessional Communication of Changes in Patient Status
Authors: Donahue Moreen  , Miller Matthew  , Smith Lisa  , Dykes Patricia  , Fitzpatrick Joyce J.
Published: February 2025

As hospitals around the globe make the transition from paper to electronic communication and documentation systems, there is a need for examining the role that electronic and non-electronic systems play in promoting effective and safe communication practices between all members of the health care team. We report here the strategies we have adopted to integrate a structured communication framework into the clinical workflow of paraprofessional providers as a means to support safe practices, to promote teamwork and to provide a key foundation for implementation of electronic clinical documentation.
Examination of Nursing Dependency for Admission Fee and Measurement of Nurses' Work Load for Nursing Care
Authors: Uto Yumiko  , Torigoe Chiaki  , Mukaikubo Sechiko  , Kumamoto Ichiro
Published: February 2025

In April 2006, a system called seven-to-one nursing system was newly introduced in acute medicine which requires intense nursing care. In April 2008, a survey was conducted using “Assessment Sheet regarding Severity of Disease / Degree of Necessity of Nursing Care at General Wards”, and obligation was established to fulfill certain requirements in medical institutions which collect the basic admission charge for the seven-to-one system. This survey is not a tool developed to investigate the amount of care required for patients but to measure the standard for the facility level. We report the findings from the comparisons of survey results for the amount of care provided to individual patients according to “The Classification of Degree of Nursing Care, Kagoshima University Edition”.
Implementation of a State Wide Online Personal Health Care Portfolio
Authors: Fauchald Thomas H.
Published: February 2025

During 2009, the State of Minnesota Department of Employee Relations will implement an online health care portfolio tool for the 50,000 employees of State government. The proposed tool is a precursor to the introduction of an online portfolio tool for the 4,000,000 citizens of the State of Minnesota in 2011. This poster presentation will report on the design and implementation of the Minnesota State Employee online health care portfolio tool and the tool's potential to reduce health care costs.
The Assessment of the Mobile Nursing Cart in Hospital Adopting
Authors: Yu Hui-Chu  , Hou I-Ching  , Hwang Yueh-Jiau
Published: February 2025

The purpose of this article was to express our assessment in mobile nursing cart adoption. The result shows the proper mobile nursing cart for the 150-160 cm height and 45-50kg weight nurses should including below requirements 1. the height should be 95-100 cm, 2. the total weight should be less then 60 kg, 3. the lowest height of the notebook arm should be 90 cm away form the ground, 4. the power supply time should be more than six hours, 5. the computer screen size should be 15 inch, 6. the cart wheel size should be 5 inch. These should be the consideration for nursing managers to purchase mobile nursing carts in the future.