bluuebunny/crossref_metadata_2025 huggingface dataset:
Polymorphisms of the oxytocin receptor gene and overeating: the intermediary role of endophenotypic risk factors
Authors: Davis C , Patte K , Zai C , Kennedy J L
Published: May 2017

Background/Objectives:

Oxytocin (OXT) is an evolutionarily ancient neuropeptide with strong links to affiliative and prosocial behaviors, and the management of stress. Increases in OXT also tend to decrease food intake, especially of sweet carbohydrates. The social correlates of low OXT levels mesh with the social deficits and stress proneness identified in interpersonal models of overeating, as well as the increased appetite for highly palatable foods typically seen in chronic overeaters. The objectives of this study were to investigate links between polymorphisms of the oxytocin receptor (OXTR) gene and overeating, and to examine OXTR links with relevant endophenotypes of overeating related to reward and stress sensitivity, and to food preferences.

Subject/Methods:

The sample comprised 460 adults between the ages of 25 and 50 years recruited from the community, and representing a broad range of body weights. Overeating, reward and punishment sensitivity, and food preferences, were quantified as composite variables using well-validated questionnaires. In addition, seven single-nucleotide polymorphisms (rs237878, rs237885, rs2268493, rs2268494, rs2254298, rs53576, rs2268498) of the OXTR gene were genotyped.

Results:

Analyses identified a four-marker haplotype that was significantly related to food preferences. Individual genotype analyses also found that at least one of the markers was related to each of the phenotypic variables. In addition, an empirically derived structural equation model linking genetic and phenotype variables produced a good fit to the data.

Conclusions:

The results of this preliminary study have demonstrated that OXTR variation is associated with overeating, and with endophenotypic traits such as sweet and fatty food preferences, and reward and punishment sensitivity. In general, the genetic findings also favor the view that overeating may be associated with relatively low basal OXT levels.
The effect of glucose-dependent insulinotropic polypeptide (GIP) variants on visceral fat accumulation in Han Chinese populations
Authors: Wang T , Ma X , Tang T , Higuchi K , Peng D , Zhang R , Chen M , Yan J , Wang S , Yan D , He Z , Jiang F , Bao Y , Jia W , Ishida K , Hu C
Published: May 2017

Objectives:

We aim to validate the effects of glucose-dependent insulinotropic polypeptide (GIP) on fat distribution and glucose metabolism in Han Chinese populations.

Methods:

We genotyped six tag single-nucleotide polymorphisms (SNPs) of GIP and four tag SNPs of glucose-dependent insulinotropic polypeptide receptor (GIPR) among 2884 community-based individuals from Han Chinese populations. Linear analysis was applied to test the associations of these variants with visceral fat area (VFA) and subcutaneous fat area (SFA) quantified by magnetic resonance imaging as well as glucose-related traits.

Results:

We found that the C allele of rs4794008 of GIP tended to increase the VFA and the VFA/SFA ratio in all subjects (P=0.050 and P=0.054, respectively), and rs4794008 was associated with the VFA/SFA ratio in males (P=0.041) after adjusting for the BMI. The VFA-increasing allele of rs4794008 was not related to any glucose metabolism traits. However, rs9904288 of GIP was associated with the SFA in males as well as glucose-related traits in all subjects (P range, 0.004–0.049), and the GIPR variants displayed associations with both fat- and glucose-related traits.

Conclusions:

The results could provide the evidence that GIP might modulate visceral fat accumulation via incretin function or independent of incretin.
CCN5/WISP-2 restores ER-∝ in normal and neoplastic breast cells and sensitizes triple negative breast cancer cells to tamoxifen
Authors: Sarkar S , Ghosh A , Banerjee S , Maity G , Das A , Larson M A , Gupta V , Haque I , Tawfik O , Banerjee S K
Published: May 2017

CCN5/WISP-2 is an anti-invasive molecule and prevents breast cancer (BC) progression. However, it is not well understood how CCN5 prevents invasive phenotypes of BC cells. CCN5 protein expression is detected in estrogen receptor-α (ER-α) -positive normal breast epithelial cells as well as BC cells, which are weakly invasive and rarely metastasize depending on the functional status of ER-α. A unique molecular relation between CCN5 and ER-α has been established as the components of the same signaling pathway that coordinate some essential signals associated with the proliferation as well as delaying the disease progression from a non-invasive to invasive phenotypes. Given the importance of this connection, we determined the role of CCN5 in regulation of ER-α in different cellular settings and their functional relationship. In a genetically engineered mouse model, induced expression of CCN5 in the mammary ductal epithelial cells by doxycycline promotes ER-α expression. Similarly, CCN5 regulates ER-α expression and activity in normal and neoplastic breast cells, as documented in various in vitro settings such as mouse mammary gland culture, human mammary epithelial cell and different BC cell cultures in the presence or absence of human recombinant CCN5 (hrCCN5) protein. Mechanistically, at least in the BC cells, CCN5 is sufficient to induce ER-α expression at the transcription level via interacting with integrins-α6β1 and suppressing Akt followed by activation of FOXO3a. Moreover, in vitro and in vivo functional assays indicate that CCN5 treatment promotes response to tamoxifen in triple-negative BC (TNBC) cells possibly via restoring ER-α. Collectively, these studies implicates that the combination treatments of CCN5 (via activation of CCN5 or hrCCN5 treatment) and tamoxifen as potential therapies for TNBC.
Heat transfer enhancement in free convection flow of CNTs Maxwell nanofluids with four different types of molecular liquids
Authors: Aman Sidra , Khan Ilyas , Ismail Zulkhibri , Salleh Mohd Zuki , Al-Mdallal Qasem M.
Published: May 2017

This article investigates heat transfer enhancement in free convection flow of Maxwell nanofluids with carbon nanotubes (CNTs) over a vertically static plate with constant wall temperature. Two kinds of CNTs i.e. single walls carbon nanotubes (SWCNTs) and multiple walls carbon nanotubes (MWCNTs) are suspended in four different types of base liquids (Kerosene oil, Engine oil, water and ethylene glycol). Kerosene oil-based nanofluids are given a special consideration due to their higher thermal conductivities, unique properties and applications. The problem is modelled in terms of PDE’s with initial and boundary conditions. Some relevant non-dimensional variables are inserted in order to transmute the governing problem into dimensionless form. The resulting problem is solved via Laplace transform technique and exact solutions for velocity, shear stress and temperature are acquired. These solutions are significantly controlled by the variations of parameters including the relaxation time, Prandtl number, Grashof number and nanoparticles volume fraction. Velocity and temperature increases with elevation in Grashof number while Shear stress minimizes with increasing Maxwell parameter. A comparison between SWCNTs and MWCNTs in each case is made. Moreover, a graph showing the comparison amongst four different types of nanofluids for both CNTs is also plotted.
Scale-integrated Network Hubs of the White Matter Structural Network
Authors: Kwon Hunki , Choi Yong-Ho , Seo Sang Won , Lee Jong-Min
Published: May 2017

The ‘human connectome’ concept has been proposed to significantly increase our understanding of how functional brain states emerge from their underlying structural substrates. Especially, the network hub has been considered one of the most important topological properties to interpret a network as a complex system. However, previous structural brain connectome studies have reported network hub regions based on various nodal resolutions. We hypothesized that brain network hubs should be determined considering various nodal scales in a certain range. We tested our hypothesis using the hub strength determined by the mean of the “hubness” values over a range of nodal scales. Some regions of the precuneus, superior occipital gyrus, and superior parietal gyrus in a bilaterally symmetric fashion had a relatively higher level of hub strength than other regions. These regions had a tendency of increasing contributions to local efficiency than other regions. We proposed a methodological framework to detect network hubs considering various nodal scales in a certain range. This framework might provide a benefit in the detection of important brain regions in the network.
Reef-building corals thrive within hot-acidified and deoxygenated waters
Authors: Camp Emma F. , Nitschke Matthew R. , Rodolfo-Metalpa Riccardo , Houlbreque Fanny , Gardner Stephanie G. , Smith David J. , Zampighi Marco , Suggett David J.
Published: May 2017

Coral reefs are deteriorating under climate change as oceans continue to warm and acidify and thermal anomalies grow in frequency and intensity. In vitro experiments are widely used to forecast reef-building coral health into the future, but often fail to account for the complex ecological and biogeochemical interactions that govern reefs. Consequently, observations from coral communities under naturally occurring extremes have become central for improved predictions of future reef form and function. Here, we present a semi-enclosed lagoon system in New Caledonia characterised by diel fluctuations of hot-deoxygenated water coupled with tidally driven persistently low pH, relative to neighbouring reefs. Coral communities within the lagoon system exhibited high richness (number of species = 20) and cover (24–35% across lagoon sites). Calcification rates for key species (Acropora formosa, Acropora pulchra, Coelastrea aspera and Porites lutea) for populations from the lagoon were equivalent to, or reduced by ca. 30–40% compared to those from the reef. Enhanced coral respiration, alongside high particulate organic content of the lagoon sediment, suggests acclimatisation to this trio of temperature, oxygen and pH changes through heterotrophic plasticity. This semi-enclosed lagoon therefore provides a novel system to understand coral acclimatisation to complex climatic scenarios and may serve as a reservoir of coral populations already resistant to extreme environmental conditions.
Experimental, quantum chemical and molecular dynamic simulations studies on the corrosion inhibition of mild steel by some carbazole derivatives
Authors: Nwankwo Henry U. , Olasunkanmi Lukman O. , Ebenso Eno E.
Published: May 2017

Five selected carbazole derivatives, namely carbazole, 3,6-dibromocarbazole, 2-hydroxycarbazole, 1,2,3,4-tetrahydrocarbazole and 9-(2-ethylhexyl)carbazole-3,6-dicarboxaldehyde were investigated for their inhibitive effects onDesulfovibrio vulgaris(D.vulgaris) induced corrosion of mild steel and in 1 M HCl medium using weight loss, potentiodynamic polarization and electrochemical impedance spectroscopy (EIS) techniques. The carbazole derivatives were found to be mixed type inhibitors with predominantly cathodic inhibitive effects for mild steel in 1 M HCl. Surface morphology results showed the compounds formed adsorbed film on mild steel surface in both aqueous acid and sulphate reducing bacteria (SRB) media. Quantum chemical calculations were used to provide molecular based explanations for the inhibitive effects of the compounds. The interactions of the molecules with mild steel surface was simulated based on molecular dynamic simulations approach using Fe(110) crystal surface as representative metallic surface.
Infants learn better from left to right: a directional bias in infants’ sequence learning
Authors: Bulf Hermann , de Hevia Maria Dolores , Gariboldi Valeria , Macchi Cassia Viola
Published: May 2017

A wealth of studies show that human adults map ordered information onto a directional spatial continuum. We asked whether mapping ordinal information into a directional space constitutes an early predisposition, already functional prior to the acquisition of symbolic knowledge and language. While it is known that preverbal infants represent numerical order along a left-to-right spatial continuum, no studies have investigated yet whether infants, like adults, organize any kind of ordinal information onto a directional space. We investigated whether 7-month-olds’ ability to learn high-order rule-like patterns from visual sequences of geometric shapes was affected by the spatial orientation of the sequences (left-to-right vs. right-to-left). Results showed that infants readily learn rule-like patterns when visual sequences were presented from left to right, but not when presented from right to left. This result provides evidence that spatial orientation critically determines preverbal infants’ ability to perceive and learn ordered information in visual sequences, opening to the idea that a left-to-right spatially organized mental representation of ordered dimensions might be rooted in biologically-determined constraints on human brain development.
Identification of Na+/K+-ATPase inhibition-independent proarrhythmic ionic mechanisms of cardiac glycosides
Authors: Koh Cai Hong , Wu Jianjun , Chung Ying Ying , Liu Zhenfeng , Zhang Rong-Rong , Chong Ketpin , Korzh Vladimir , Ting Sherwin , Oh Steve , Shim Winston , Tian Hai-Yan , Wei Heming
Published: May 2017

The current study explored the Na+/K+-ATPase (NKA) inhibition-independent proarrhythmic mechanisms of cardiac glycosides (CGs) which are well-known NKA inhibitors. With the cytosolic Ca2+ chelated by EGTA and BAPTA or extracellular Ca2+ replaced by Ba2+, effects of bufadienolides (bufalin (BF) and cinobufagin (CBG)) and cardenolides (ouabain (Oua) and pecilocerin A (PEA)) on the L-type calcium current (ICa,L) were recorded in heterologous expression Cav1.2-CHO cells and human embryonic stem cell-derived cardiomyocytes (hESC-CMs). BF and CBG demonstrated a concentration-dependent (0.1 to 100 µM) ICa,L inhibition (maximal ≥50%) without and with the NKA activity blocked by 10 µM Oua. BF significantly shortened the action potential duration at 1.0 µM and shortened the extracellular field potential duration at 0.01~1.0 µM. On the other hand, BF and CBG at 100 µM demonstrated a strong inhibition (≥40%) of the rapidly activating component of the delayed rectifier K+ current (IKr) in heterologous expression HEK293 cells and prolonged the APD of the heart of day-3 Zebrafish larva with disrupted rhythmic contractions. Moreover, hESC-CMs treated with BF (10 nM) for 24 hours showed moderate yet significant prolongation in APD90. In conclusion, our data indicate that CGs particularly bufadienolides possess cytosolic [Ca2+]i- and NKA inhibition- independent proarrhythmic potential through ICa,L and IKr inhibitions.
Decadal Variations in Eastern Canada’s Taiga Wood Biomass Production Forced by Ocean-Atmosphere Interactions
Authors: Boucher Etienne , Nicault Antoine , Arseneault Dominique , Bégin Yves , Karami Mehdi Pasha
Published: May 2017

Across Eastern Canada (EC), taiga forests represent an important carbon reservoir, but the extent to which climate variability affects this ecosystem over decades remains uncertain. Here, we analyze an extensive network of black spruce (Picea mariana Mill.) ring width and wood density measurements and provide new evidence that wood biomass production is influenced by large-scale, internal ocean-atmosphere processes. We show that while black spruce wood biomass production is primarily governed by growing season temperatures, the Atlantic ocean conveys heat from the subtropics and influences the decadal persistence in taiga forests productivity. Indeed, we argue that 20–30 years periodicities in Sea Surface Temperatures (SSTs) as part of the the Atlantic Multi-decadal Oscillation (AMO) directly influence heat transfers to adjacent lands. Winter atmospheric conditions associated with the North Atlantic Oscillation (NAO) might also impact EC’s taiga forests, albeit indirectly, through its effect on SSTs and sea ice conditions in surrounding seas. Our work emphasizes that taiga forests would benefit from the combined effects of a warmer atmosphere and stronger ocean-to-land heat transfers, whereas a weakening of these transfers could cancel out, for decades or longer, the positive effects of climate change on Eastern Canada’s largest ecosystem.
In vivo imaging of uterine cervix with a Mueller polarimetric colposcope
Authors: Vizet Jérémy , Rehbinder Jean , Deby Stanislas , Roussel Stéphane , Nazac André , Soufan Ranya , Genestie Catherine , Haie-Meder Christine , Fernandez Hervé , Moreau François , Pierangelo Angelo
Published: May 2017

Mueller polarimetric imaging enables the detection and quantification of modifications of the collagen fibers in the uterine cervix due to the development of a precancerous lesion. This information is not accessible through the use of the classic colposcope, a low magnification microscope used in current practice for cervical cancer screening. However, the in vivo application of Mueller polarimetric imaging poses an instrumental challenge: the device should be sufficiently compact, while still being able to perform fast and accurate acquisition of Mueller matrices in real-world conditions. In this study, the first wide field Mueller Polarimetric Colposcope (MPC) for the in vivo analysis of uterine cervix is presented. The MPC has been fabricated by grafting a miniaturized Mueller polarimetric imager on a classic colposcope. This new imaging tool performs the fast acquisition of Mueller polarimetric images, thus eliminating any blurring effects due to patient movements. It can be easily used by a practitioner with little change to their existing practice. Finally, the MPC was tested in vivo on a number of patients in the field.
Advantages and problems of nonlinear methods applied to analyze physiological time signals: human balance control as an example
Authors: Müller Wolfram , Jung Alexander , Ahammer Helmut
Published: May 2017

Physiological processes are regulated by nonlinear dynamical systems. Various nonlinear measures have frequently been used for characterizing the complexity of fractal time signals to detect system features that cannot be derived from linear analyses. We analysed human balance dynamics ranging from simple standing to balancing on one foot with closed eyes to study the inherent methodological problems when applying fractal dimension analysis toreal-worldsignals. Higuchi dimension was used as an example. Choice of measurement and analysis parameters has a distinct influence on the computed dimension. Noise increases the fractional dimension which may be misinterpreted as a higher complexity of the signal. Publications without specifying the parameter setting, or without analysing the noise-sensitivity are not comparable to findings of others and therefore of limited scientific value.
The pPSU Plasmids for Generating DNA Molecular Weight Markers
Authors: Henrici Ryan C. , Pecen Turner J. , Johnston James L. , Tan Song
Published: May 2017

Visualizing nucleic acids by gel electrophoresis is one of the most common techniques in molecular biology, and reference molecular weight markers or ladders are commonly used for size estimation. We have created the pPSU1 & pPSU2 pair of molecular weight marker plasmids which produce both 100 bp and 1 kb DNA ladders when digested with two common restriction enzymes. The 100 bp ladder fragments have been optimized to migrate appropriately on both agarose and native polyacrylamide, unlike many currently available DNA ladders. Sufficient plasmid DNA can be isolated from 100 ml E. coli cultures for the two plasmids to produce 100 bp or 1 kb ladders for 1000 gels. As such, the pPSU1 and pPSU2 plasmids provide reference fragments from 50 to 10000 bp at a fraction of the cost of commercial DNA ladders. The pPSU1 and pPSU2 plasmids are available without licensing restrictions to nonprofit academic users, affording freely available high-quality, low-cost molecular weight standards for molecular biology applications.
Quantification of hepatocellular carcinoma heterogeneity with multiparametric magnetic resonance imaging
Authors: Hectors Stefanie J. , Wagner Mathilde , Bane Octavia , Besa Cecilia , Lewis Sara , Remark Romain , Chen Nelson , Fiel M. Isabel , Zhu Hongfa , Gnjatic Sacha , Merad Miriam , Hoshida Yujin , Taouli Bachir
Published: May 2017

Tumour heterogeneity poses a significant challenge for treatment stratification. The goals of this study were to quantify heterogeneity in hepatocellular carcinoma (HCC) using multiparametric magnetic resonance imaging (mpMRI), and to report preliminary data correlating quantitative MRI parameters with advanced histopathology and gene expression in a patient subset. Thirty-two HCC patients with 39 HCC lesions underwent mpMRI including diffusion-weighted imaging (DWI), blood-oxygenation-level-dependent (BOLD), tissue-oxygenation-level-dependent (TOLD) and dynamic contrast-enhanced (DCE)-MRI. Histogram characteristics [central tendency (mean, median) and heterogeneity (standard deviation, kurtosis, skewness) MRI parameters] in HCC and liver parenchyma were compared using Wilcoxon signed-rank tests. Histogram data was correlated between MRI methods in all patients and with histopathology and gene expression in 14 patients. HCCs exhibited significantly higher intra-tissue heterogeneity vs. liver with all MRI methods (P < 0.030). Although central tendency parameters showed significant correlations between MRI methods and with each of histopathology and gene expression, heterogeneity parameters exhibited additional complementary correlations between BOLD and DCE-MRI and with histopathologic hypoxia marker HIF1α and gene expression of Wnt target GLUL, pharmacological target FGFR4, stemness markers EPCAM and KRT19 and immune checkpoint PDCD1. Histogram analysis combining central tendency and heterogeneity mpMRI features is promising for non-invasive HCC characterization on the imaging, histologic and genomics levels.
Ultrasensitive multiplexed immunoassay of autophagic biomarkers based on Au/rGO and Au nanocages amplifying electrochemcial signal
Authors: Wang Guannan , Li Yankun , Liu Jinlei , Yuan Yajing , Shen Zhaoliang , Mei Xifan
Published: May 2017

A novel sandwich-assay electrochemical immunosensor for simultaneous determination of autophagic biomarkers was introduced for the first time, the gold-reduced grapheme oxide nanocomposite (Au/r-GO) set as a good conductive platform with super high specific area, and provided more binding sites for the both antibodies of Beclin-1 and LC3B-II. While Au nanocages (AuNCs) served as good conductive platform to encapsulate a large amount of redox probe and secondary antibodies for signal amplification, due to the abundant reactive oxygen functional groups on its surface. Through differential pulse voltammetry (DPV) measurements, two separate signals can be detected directly in a single run, which represent the existence of Belin-1 and LC3B-II. Under optimized conditions, the electrochemical immunosensor exhibited good sensitivity and selectivity for the simultaneous determination of Beclin-1 and LC3B-II with linear ranges of 0.1–100 ng/mL. The detection limit for Beclin-1 and LC3B-II is 0.02 and 0.03 ng/mL respectively. This method was also applied for the analysis of Beclin-1 and LC3B-II levels in experimental cellular protein lysates, and the results were in good agreement with those of enzyme linked immunosorbent assay. This approach gives a promising simple, sensitive and quantitative strategy for the detection of autophagy
Erratum: OncoScore: a novel, Internet-based tool to assess the oncogenic potential of genes
Authors: Piazza Rocco , Ramazzotti Daniele , Spinelli Roberta , Pirola Alessandra , De Sano Luca , Ferrari Pierangelo , Magistroni Vera , Cordani Nicoletta , Sharma Nitesh , Gambacorti-Passerini Carlo
Published: May 2017

Scientific Reports 7: Article number: 46290; published online: 07 April 2017; updated: 22 May 2017 The original version of this Article incorrectly listed all author names in reverse. The author list now reads: Rocco Piazza, Daniele Ramazzotti, Roberta Spinelli, Alessandra Pirola, Luca De Sano, Pierangelo Ferrari, Vera Magistroni, Nicoletta Cordani, Nitesh Sharma & Carlo Gambacorti-Passerini.
Retraction Note: Circulating plant miRNAs can regulate human gene expression in vitro
Authors: Pastrello Chiara , Tsay Mike , McQuaid Rosanne , Abovsky Mark , Pasini Elisa , Shirdel Elize , Angeli Marc , Tokar Tomas , Jamnik Joseph , Kotlyar Max , Jurisicova Andrea , Kotsopoulos Joanne , El-Sohemy Ahmed , Jurisica Igor
Published: May 2017

We are retracting this Article as we no longer have confidence in the data to support our central conclusion – the detection of Brassica oleracea microRNAs in the bloodstream of humans who consumed broccoli.
Correction: Corrigendum: Cochlear gene therapy with ancestral AAV in adult mice: complete transduction of inner hair cells without cochlear dysfunction
Authors: Suzuki Jun , Hashimoto Ken , Xiao Ru , Vandenberghe Luk H. , Liberman M. Charles
Published: May 2017

Scientific Reports 7: Article number: 45524; published online: 3 April 2017; updated: 22 May 2017 The authors forgot to cite previous studies relating to in vivo studies in newborn mice. These additional references are listed below as references 1 and 2, and should appear in the text as below. In the Introduction section,
Self-assembling peptide and protein amyloids: from structure to tailored function in nanotechnology
Authors: Wei Gang , Su Zhiqiang , Reynolds Nicholas P. , Arosio Paolo , Hamley Ian W. , Gazit Ehud , Mezzenga Raffaele
Published: May 2017

Self-assembling amyloid materials with various length scales and tailored functions show wide applications in the fields of biomedicine, tissue engineering, energy materials, environmental science, nanodevices, biosensors, optical materials and liquid crystals.
Carbon-containing bone hydroxyapatite obtained from tuna fish bone with high adsorption performance for Congo red
Authors: Peng Qifan , Yu Fan , Huang Bicheng , Huang Yaqin
Published: May 2017

Carbon-containing nano-hydroxyapatite derived from fish bone was prepared as a high performance adsorbent for water treatment.
Correction: Predictive chromatography of peptides and proteins as a complementary tool for proteomics
Authors: Tarasova Irina A. , Masselon Christophe D. , Gorshkov Alexander V. , Gorshkov Mikhail V.
Published: May 2017

Correction for ‘Predictive chromatography of peptides and proteins as a complementary tool for proteomics’ by Irina A. Tarasova et al., Analyst, 2016, 141, 4816–4832.
Nondestructive detection of triclosan in antibacterial hand soaps using digitally labelled Raman spectroscopy
Authors: Han Xi , Tan Zong , Huang Zhixuan , Chen Xiaodong , Gong Yan , Li Qifeng , Xu Kexin , Chen Da
Published: May 2017

Digital labeled Raman spectroscopy enables nondestructive detection of triclosan in hand soaps, revealing the feasibility of digital separation in practice.
Integrated microfluidic chip with nanobiosensor for rapid and label-free detection of a specific gene
Authors: Zhang Congxiao , Lv Xuefei , Yasmeen Saeed , Qing Hong , Deng Yulin
Published: May 2017

Biomolecular detection techniques are tending to develop in terms of miniaturization, automation, rapidity, sensitivity and low cost, and these techniques are urgently needed as “point of care tests” or “rapid tests” in clinical diagnosis, environmental monitoring and food safety.
Laser-based ambient mass spectrometry
Authors: Cheng Sy-Chyi , Shiea Christopher , Huang Yeou-Lih , Wang Chin-Hsiung , Cho Yi-Tzu , Shiea Jentaie
Published: May 2017

This study summarized laser-based ambient mass spectrometric (AMS) techniques with regard to their fundamentals, ionization mechanisms, and recent applications.
Square wave voltammetry enables fast quantification and evaluation of Bi3+extraction from eyeshadow samples
Authors: Ribeiro L. A. R. , Pradela-Filho L. A. , Fonseca W. T. , Araújo D. A. G. , Assunção R. M. N. , Takeuchi R. M. , Santos A. L.
Published: May 2017

Square wave voltammetry provides fast quantification of Bi3+in eyeshadows and effective evaluation of Bi3+extraction from these samples.
Fluorescence properties and analytical applications of covalent organic frameworks
Authors: Xue Rui , Guo Hao , Wang Ting , Gong Li , Wang Yanni , Ai Jiebing , Huang Dongdong , Chen Huiqin , Yang Wu
Published: May 2017

Fluorescent COFs with large π-conjugated building units and inherent rigid structure have important potential for chemosensing detection of target molecules or ions based on turn-on and turn-off modes.
Metallocorroles as inherently chiral chromophores: resolution and electronic circular dichroism spectroscopy of a tungsten biscorrole
Authors: Schies Christine , Alemayehu Abraham B. , Vazquez-Lima Hugo , Thomas Kolle E. , Bruhn Torsten , Bringmann Gerhard , Ghosh Abhik
Published: May 2017

A homoleptic tungsten biscorrole, an inherently chiral chromophore, has been resolved and characterized using electronic circular dichroism spectroscopy.
Fe3O4@HKUST-1 and Pd/Fe3O4@HKUST-1 as magnetically recyclable catalysts prepared via conversion from a Cu-based ceramic
Authors: Toyao Takashi , Styles Mark J. , Yago Tokuichiro , Sadiq Muhammad M. , Riccò Raffaele , Suzuki Kiyonori , Horiuchi Yu , Takahashi Masahide , Matsuoka Masaya , Falcaro Paolo
Published: May 2017

A Fe3O4/Cu- ceramic system converted into a magnetic HKUST-1 composite was used as a recyclable catalyst for one-pot cascade and hydrogenation reactions.
First 3D-printed complex inorganic polycrystalline scintillator
Authors: Dosovitskiy G. A. , Karpyuk P. V. , Evdokimov P. V. , Kuznetsova D. E. , Mechinsky V. A. , Borisevich A. E. , Fedorov A. A. , Putlayev V. I. , Dosovitskiy A. E. , Korjik M. V.
Published: May 2017

Polycrystalline scintillator YAG:Ce was 3D-printed using stereophotolithography and sintered; it has shown light yield 60% higher than YAG:Ce single crystal.
Optimization of hydrophilic/hydrophobic phase separation in sPEEK membranes by hydrothermal treatments
Authors: Mendil-Jakani H. , Zamanillo López I. , Mareau V. H. , Gonon L.
Published: May 2017

The swelling behavior of sPEEK membranes: a thermally activated process associated to the β-relaxation crossover.
13-cis-Retinoic acid on coinage metals: hierarchical self-assembly and spin generation
Authors: Zhang Xue , Li Na , Zhang Yajie , Berndt Richard , Wang Yongfeng
Published: May 2017

Hierarchical self-assembly of 13-cis-retinoic acid on Au(111) and Ag(111) was investigated using low-temperature scanning tunnelling microscopy.
The Rashba effect and indirect electron–hole recombination in hybrid organic–inorganic perovskites
Authors: Yu Zhi-Gang
Published: May 2017

Slow electron–hole recombination, characterized by the bimolecular coefficient k2 in hybrid organic–inorganic perovskites (HOIPs), can be quantitatively accounted for by phonon-assisted processes.
New synthetic routes towards MOF production at scale
Authors: Rubio-Martinez Marta , Avci-Camur Ceren , Thornton Aaron W. , Imaz Inhar , Maspoch Daniel , Hill Matthew R.
Published: May 2017

The potential commercial applications for metal organic frameworks (MOFs) are tantalizing.
Oxidation of the hexagonal Mo2C(101) surface by H2O dissociative adsorption
Authors: Tian Xinxin , Wang Tao , Jiao Haijun
Published: May 2017

Oxidation of the hexagonal Mo2C(101) surface by H2O dissociative adsorption was investigated using periodic density functional theory.
Exploring the boundaries of direct detection and characterization of labile isomers – a case study of copper(ii)–dipeptide systems
Authors: Tóth Eszter N. , May Nóra V. , Rockenbauer Antal , Peintler Gábor , Gyurcsik Béla
Published: May 2017

Preferential peptide vs. histamine type coordination was directly observed upon increasing temperature by spectroscopic techniques in copper(ii) His-Xaa dipeptide microequilibria.
Boron-doped graphitic carbon nitride nanosheets for enhanced visible light photocatalytic water splitting
Authors: Thaweesak Supphasin , Wang Songcan , Lyu Miaoqiang , Xiao Mu , Peerakiatkhajohn Piangjai , Wang Lianzhou
Published: May 2017

A new type of boron-doped graphitic carbon nitride (B-g-C3N4) nanosheets was prepared by a benign one-pot thermal polycondensation process.
A journey through ternary lead chlorido tungstates by thermal scanning
Authors: Mos-Hummel Agnieszka , Ströbele Markus , Meyer H.-Jürgen
Published: May 2017

The reaction of WCl6with lead powder affords six new compounds, all monitored in one DSC run, and characterized by XRD techniques.
Echinacoside ameliorates the memory impairment and cholinergic deficit induced by amyloid beta peptides via the inhibition of amyloid deposition and toxicology
Authors: Shiao Young-Ji , Su Muh-Hwan , Lin Hang-Ching , Wu Chi-Rei
Published: May 2017

This study investigates the role of the amyloid cascade and central neuronal function on the protective effects of echinacoside in amyloid β peptide 1-42 (Aβ 1-42)-treated SH-SY5Y cells and an Aβ 1-42-infused rat.
Antihypertensive and antioxidant effects of supplementation with red wine pomace in spontaneously hypertensive rats
Authors: Del Pino-García Raquel , Rivero-Pérez María D. , González-SanJosé María L. , Croft Kevin D. , Muñiz Pilar
Published: May 2017

4-Week supplementation with a new red wine pomace seasoning (RWPS) decreased blood pressure, ameliorated vascular oxidative stress, and improved NO bioavailability in Spontaneously Hypertensive Rats (SHR).
A solid acetylene reagent with enhanced reactivity: fluoride-mediated functionalization of alcohols and phenols
Authors: Werner Georg , Rodygin Konstantin S. , Kostin Anton A. , Gordeev Evgeniy G. , Kashin Alexey S. , Ananikov Valentine P.
Published: May 2017

The direct vinylation of an OH group in alcohols and phenols was carried out utilizing an easy-to-use CaC2/KF solid acetylene reagent.
Correction: Core-substituted naphthalenediimides anchored on BiVO4 for visible light-driven water splitting
Authors: Hernández Simelys , Ottone Carminna , Proto Stefano , Tolod Kristine Rodulfo , de los Bernardos Miriam Díaz , Solé-Daura Albert , Carbó Jorge J. , Godard Cyril , Castillón Sergio , Russo Nunzio , Saracco Guido , Claver Carmen
Published: May 2017

Correction for ‘Core-substituted naphthalenediimides anchored on BiVO4 for visible light-driven water splitting’ by Simelys Hernández et al., Green Chem., 2017, 19, 2448–2462.
An automated and portable microfluidic chemiluminescence immunoassay for quantitative detection of biomarkers
Authors: Hu Binfeng , Li Juanjuan , Mou Lei , Liu Yong , Deng Jinqi , Qian Wei , Sun Jiashu , Cha Ruitao , Jiang Xingyu
Published: May 2017

An automated and portable microfluidic chemiluminescence immunoassay is developed for quantitative detection of biomarkers in serum samples.
Literature-based prediction of novel drug indications considering relationships between entities
Authors: Jang Giup , Lee Taekeon , Lee Byung Mun , Yoon Youngmi
Published: May 2017

There have been many attempts to identify and develop new uses for existing drugs, which is known as drug repositioning.
Assessing the performance of docking scoring function, FEP, MM-GBSA, and QM/MM-GBSA approaches on a series of PLK1 inhibitors
Authors: Pu Chunlan , Yan Guoyi , Shi Jianyou , Li Rui
Published: May 2017

The ranking capability of FEP is the best withrs= 0.854. QM/MM-GBSA can reach 0.767 with much lower computation time.
Improved photovoltaic performance of quantum dot-sensitized solar cells using multi-layered semiconductors with the effect of a ZnSe passivation layer
Authors: Subramanian Archana , Punnoose Dinah , Rao Sunkara Srinivasa , Venkata Thulasi Varma Chebrolu , Naresh Bandari , Raman Vivekanandan , Kim Hee-Je
Published: May 2017

ZnSe was deposited on a TiO2/PbS/CdS/CdSe photoanode, which was more efficient in reducing electron recombination in the QDSSCs.
Series of high spin mononuclear iron(iii) complexes with Schiff base ligands derived from 2-hydroxybenzophenones
Authors: Pogány Lukáš , Moncol Ján , Pavlik Ján , Šalitroš Ivan
Published: May 2017

Utilization of 2-hydroxybenzophenone derivatives for the preparation of iron(iii) Schiff base complexes resulted in a series of high-spin, mostly antiferromagnetically coupled systems.
Rational design, fabrication and characterization of a thiol-rich 3D-porous hypercrosslink polymer as a new engineered Hg2+ sorbent: enhanced selectivity and uptake
Authors: Abadast Fatemeh , Mouradzadegun Arash , Ganjali Mohammad Reza
Published: May 2017

A new synergy between a porous matrix and active sites was developed to form a heterogeneous adsorbent for high efficiency and high selectivity mercury removal in drinking water.
A sensitive Pb2+ testing method based on aptamer-functionalized peroxidase-like 3D-flower MoS2 microspheres
Authors: Wang Xiu , Yang Chunlei , Yan Mei , Yu Jinghua
Published: May 2017

We, herein, report a sensitive EC bioanalytical protocol for the detection of Pb2+ based on AuPt–MCNTs as a platform and 3D-flower MoS2–GR hybrids as signal probes. This method showed a good linear relationship between the current response and the Pb2+ concentration. It can be widely utilized for the identification of other target molecules.
A facile route to prepare dimeric BODIPY-based porous organic polymers using FeCl3
Authors: Wang De-Gao , Song Fan , Tang Hui , Jia Xin-Ru , Song Min , Kuang Gui-Chao
Published: May 2017

A facile FeCl3 catalyzed oxidation of the dimeric BODIPY monomers with different spacers to construct porous organic polymers have been reported. These polymers’ singlet oxygen generation capacities are dependent on the spacers.
Bifunctional antimicrobial conjugates and hybrid antimicrobials
Authors: Klahn P. , Brönstrup M.
Published: May 2017

Novel antimicrobial drugs are continuously needed to counteract bacterial resistance development.
New selenosteroids as antiproliferative agents
Authors: Fuentes-Aguilar Alma , Romero-Hernández Laura L. , Arenas-González Ailed , Merino-Montiel Penélope , Montiel-Smith Sara , Meza-Reyes Socorro , Vega-Báez José Luis , Plata Gabriela B. , Padrón José M. , López Óscar , Fernández-Bolaños José G.
Published: May 2017

A wide panel of new selenosteroids have been prepared as new antiproliferative agents; improved activities were achieved compared to commonly-used chemotherapeutic agents.
Is more better? A comparison of tri- and tetrapeptidic catalysts
Authors: Schnitzer Tobias , Wiesner Markus , Krattiger Philipp , Revell Jefferson D. , Wennemers Helma
Published: May 2017

From an enzymatic perspective, there is a general notion that the bigger and more complex a catalytically active peptide is the more enzyme-like and the better it should become. But is this really true?
Active metal template synthesis of a neutral indolocarbazole-containing [2]rotaxane host system for selective oxoanion recognition
Authors: Brown Asha , Lang Thomas , Mullen Kathleen M. , Beer Paul D.
Published: May 2017

A CuAAC active metal template approach is used to prepare a new neutral indolocarbazole-containing [2]rotaxane anion host system which exhibits a rare interlocked host selectivity for oxoanions over halides.
Kinetic and mechanistic investigation for the copolymerization of CO2 and cyclohexene oxide catalyzed by trizinc complexes
Authors: Xu Yonghang , Lin Limiao , He Chun-Ting , Qin Jiaxiang , Li Zhong , Wang Shuanjin , Xiao Min , Meng Yuezhong
Published: May 2017

The mechanism of CO2/epoxide copolymerization catalyzed by Schiff base trizinc complexes.
Aromatic diselenide crosslinkers to enhance the reprocessability and self-healing of polyurethane thermosets
Authors: An Xiaowei , Aguirresarobe Robert H. , Irusta Lourdes , Ruipérez Fernando , Matxain Jon M. , Pan Xiangqiang , Aramburu Nora , Mecerreyes David , Sardon Haritz , Zhu Jian
Published: May 2017

We explore the utilization of aromatic diselenides as new low temperature exchangeable monomers for their utilization in thermosets.
Carbon quantum dot sensitized Pt@Bi2WO6/FTO electrodes for enhanced photoelectro-catalytic activity of methanol oxidation
Authors: Zheng Huajun , Niu Ping , Zhao Zhefei
Published: May 2017

Carbon quantum dots (CQDs) sensitized Pt@Bi2WO6/FTO electrodes (simplified as CQDs-Pt@Bi2WO6/FTO) were prepared by loading platinum particles onto Bi2WO6 nanoplates via a photo-deposition method and sensitized CQDs via a dip-coating method.
Influence of O2, H2O and airborne hydrocarbons on the properties of selected 2D materials
Authors: Peng Zhenbo , Yang Rui , Kim Min A. , Li Lei , Liu Haitao
Published: May 2017

Adsorption of molecules from the ambient environment significantly changes the optical, electrical, electrochemical, and tribological properties of 2D materials.
Heterostructured Bi2O3/Bi2MoO6 nanocomposites: simple construction and enhanced visible-light photocatalytic performance
Authors: He Qiong , Ni Yonghong , Ye Shiyong
Published: May 2017

Heterostructured Bi2O3/Bi2MoO6 nanocomposites with enhanced visible-light photocatalytic activity are successfully constructed by a simple two-step route, employing Bi(NO3)3 and Na2MoO4 as the main raw materials in the presence of PVP.
Oxide-derived nanostructured metallic-glass electrodes for efficient electrochemical hydrogen generation
Authors: Gao Shenghan , Jia Jili , Chen Shuangqin , Luan Hengwei , Shao Yang , Yao Kefu
Published: May 2017

Nanostructured materials with large surface areas are continuing to be at the forefront of catalytic applications.
High-performance graphene-based flexible heater for wearable applications
Authors: Lin Shu-Yu , Zhang Tian-Yu , Lu Qi , Wang Dan-Yang , Yang Yi , Wu Xiao-Ming , Ren Tian-Ling
Published: May 2017

A graphene-based flexible heater with low driving voltage and ultrafast response time.
Ferrite-based soft and hard magnetic structures by extrusion free-forming
Authors: Peng Erwin , Wei Xiangxia , Herng Tun Seng , Garbe Ulf , Yu Dehong , Ding Jun
Published: May 2017

Simple fabrication of a ferrite-based bulk soft magnet (NiFe2O4) and hard magnet (BaFe12O19) using the extrusion free-forming process.
Efficient fabrication methodology of wide angle black silicon for energy harvesting applications
Authors: Gouda Abdelaziz M. , Allam Nageh K. , Swillam Mohamed A.
Published: May 2017

In this paper, we report an easy and relatively cost effective fabrication technique of a wide band omnidirectional antireflective black silicon surface based on silicon nanowires (SiNWs).
Chromium nitride as a stable cathode current collector for all-solid-state thin film Li-ion batteries
Authors: Filippin Alejandro N. , Rawlence Michael , Wäckerlin Aneliia , Feurer Thomas , Zünd Tanja , Kravchyk Kostiantyn , Kovalenko Maksym V. , Romanyuk Yaroslav E. , Tiwari Ayodhya N. , Buecheler Stephan
Published: May 2017

The development of highly oxidation resistant current collectors that are inert against lithium at elevated temperatures and high potentials is essential for the realization of high performance thin film solid state lithium based batteries.
Controlled preparation of Ag nanoparticles on graphene with different amount of defects for surface-enhanced Raman scattering
Authors: Qin Jun , Pan Lujun , Li Chengwei , Xia Lichen , Zhou Nan , Huang Yingying , Zhang Yi
Published: May 2017

Graphene with different amounts of defects was prepared by chemical vapor deposition by controlling the flow rate of hydrogen, on which Ag nanoparticles (NPs) were deposited by magnetron sputtering.
Assessing the performance and microbial structure of biofilms adhering on aerated membranes for domestic saline sewage treatment
Authors: Tian Hailong , Liu Jie , Feng Tengteng , Li Haifeng , Wu Xiaolei , Li Baoan
Published: May 2017

MABR for effective treatment of domestic saline sewage and its microbial community.
Relationship between the dipole moment of self-assembled monolayers incorporated in graphene transistors and device electrical stabilities
Authors: Ku Gwang Mo , Lee Eunho , Kang Boseok , Lee Jung Hun , Cho Kilwon , Lee Wi Hyoung
Published: May 2017

The effects of SAMs on the electrical stabilities of graphene FETs were examined by using various SAMs.
Oxygen-vacancy-promoted catalytic wet air oxidation of phenol from MnOx–CeO2
Authors: Ma Changjian , Wen Yaoyao , Yue Qingqing , Li Anqi , Fu Jile , Zhang Nouwei , Gai Hengjun , Zheng Jinbao , Chen Bing H.
Published: May 2017

The presence of oxygen vacancies can promote the formation of active oxygen species, which is essential for phenol oxidation.
Controlled synthesis of Sn-based oxides via a hydrothermal method and their visible light photocatalytic performances
Authors: Wang Jinghui , Li Hui , Meng Sugang , Ye Xiangju , Fu Xianliang , Chen Shifu
Published: May 2017

Controlled synthesize of Sn-oxides was achieved via a facile hydrothermal method with SnCl2 as precursor. A visible light photocatalytic activity of SnO2 can be induced by doping with Sn2+ or coupling with SnO.
Transformation of bioethanol to 1,3-butadiene and other bulk chemicals over the surface of Mg–Al catalysts
Authors: Gao Meixiang , Zhang Minhua , Li Yonghui
Published: May 2017

The synthesis of bulk chemicals from bioethanol and analysis of the product distribution over Mg–Al catalysts were investigated.
Bioactive composition of Reevesia formosana root and stem with cytotoxic activity potential
Authors: Chang Hsun-Shuo , Lin Chu-Hung , Hsiao Pei-Yu , Peng Hung-Ti , Lee Shiow-Ju , Cheng Ming-Jen , Chen Ih-Sheng
Published: May 2017

Three lignanoids and three terpenoids, along with 40 known compounds were isolated from Reevesia formosana.
High-efficiency perovskite solar cells employing a conjugated donor–acceptor co-polymer as a hole-transporting material
Authors: Yu Ze , Zhang Yuchen , Jiang Xiaoqing , Li Xiaoxin , Lai Jianbo , Hu Maowei , Elawad Mohammed , Gurzadyan Gagik G. , Yang Xichuan , Sun Licheng
Published: May 2017

In this work, we have successfully demonstrated that molecularly p-doping of donor–acceptor co-polymer PCPDTBT as an efficient hole-transporting material in perovskite solar cells with a decent power conversion efficiency of 15.1%.
Colloidal quantum dots for optoelectronics
Authors: Litvin A. P. , Martynenko I. V. , Purcell-Milton F. , Baranov A. V. , Fedorov A. V. , Gun'ko Y. K.
Published: May 2017

This review is focused on new concepts and recent progress in the development of three major quantum dot (QD) based optoelectronic devices: photovoltaic cells, photodetectors and LEDs.
A self-stabilized suspension catholyte to enable long-term stable Li–S flow batteries
Authors: Xu Song , Zhang Lan , Zhang Xiangping , Cai Yingjun , Zhang Suojiang
Published: May 2017

A self-stabilized suspension catholyte with long-term physical and electrochemical stability is enabled by pie-structured sulfur-Ketjenblack@reduced graphene oxide (S-KB@rGO).
Amphiphilic SiO2 hybrid aerogel: an effective absorbent for emulsified wastewater
Authors: Gao Xiang-Dong , Huang Yu-Di , Zhang Tong-Tong , Wu Yong-Qing , Li Xiao-Min
Published: May 2017

Amphiphilic SiO2–chitosan hybrid aerogel demonstrates rapid and high-efficiency absorption of a high-concentration polyacrylic emulsion or machining emulsified wastewater.
Porphyrin–graphene oxide frameworks for long life sodium ion batteries
Authors: Kumar Nanjundan Ashok , Gaddam Rohit Ranganathan , Suresh Moorthy , Varanasi Srinivasa Rao , Yang Dongfang , Bhatia Suresh K. , Zhao X. S.
Published: May 2017

Porphyrin–graphene oxide frameworks for ambient temperature sodium-ion storage are investigated. The presence of porphyrin caters for a stronger sodium ion–electrode interaction to realize high-performance sodium-ion batteries, which deliver a capacity of ∼200 mA h g−1even after resting for one month.
Facile fabrication of foldable electrospun polyacrylonitrile-based carbon nanofibers for flexible lithium-ion batteries
Authors: Chen Renzhong , Hu Yi , Shen Zhen , Pan Peng , He Xia , Wu Keshi , Zhang Xiangwu , Cheng Zhongling
Published: May 2017

To enable electrospun polyacrylonitrile-based C nanofibers (CNFs) to be employed as anode materials in flexible Li-ion batteries, it is essential to overcome their frangibility and enhance their flexibility.
A simple electrochemical route to metallic phase trilayer MoS2: evaluation as electrocatalysts and supercapacitors
Authors: Ejigu Andinet , Kinloch Ian A. , Prestat Eric , Dryfe Robert A. W.
Published: May 2017

The development of a simple, scalable and reproducible technique for the synthesis of two-dimensional metallic phase MoS2nanosheets is of paramount importance in the field of catalysis and energy storage devices.