bluuebunny/crossref_metadata_2025 huggingface dataset:
Study of sexual side effects in patients undergoing treatment with anti-depressants
Authors: Martin Alexander , Singh Manpreet , Verma Gaurav
Published: November 2022

Sexual side effects with psychotropic medications can cause major distress. Antidepressants are known to cause sexual side effects.

To study the sexual side effects in patients undergoing treatment with anti-depressants.

Sixty patients of both genders undergoing treatment with antidepressants and having sexual complaints due to medicines were evaluated. A semi structured questionnaire was used to record demographic details. Arizona Sexual Experience Scale (ASEX) was used to assess sexual dysfunction.

In our study majority patients were males 42 (70%) and diagnosed as having major depressive disorder 51 (85%). SSRIs were main agent responsible for the same 46 (76.7%).

Majority patients reported sexual side effects with antidepressants which can affect their subjective quality of life. Hence, patients should be assessed properly for sexual issues and treated accordingly.
An audit of nephrectomy: A prospective study in a tertiary care hospital in Eastern India
Authors: Ray Amit , Mondal Partha Protim , Haldar Purba , Bera Malay Kumar
Published: November 2022

Nephrectomy means surgical removal of irreversibly damaged kidney by various disease processes, injury and congenital anomalies or en block removal of kidneys along with renal tumors.

Objective of the study is to gather information and analyze nephrectomies performed at in a tertiary care hospital of Eastern India.

A prospective observational study of nephrectomies performed during three years from April 2012 to March 2015   in a tertiary care hospital of Eastern India regarding their demographic study, clinical presentation, indications, postoperative complications and histopathological report.

A total of 106 nephrectomies were performed during the study period. The male to female ratio was 1.3:1 (60:46).  Left sided nephrectomies were more common than right side 1.3 :1 (60:46). The indications were renal malignancy in 57.5 % (61) cases others were benign conditions 42.5% (45) leading to non -functioning or poorly functioning kidneys. In the benign conditions, renal stone 22 (48.9%), neglected ureteropelvic junction obstruction 11(24.4%), chronic pyelonephritis 5 (11.1% ), renal tuberculosis  4   (8.9%), polycystic kidney disease 2(4.4%), renal trauma 1(2.2%). Malignant diseases were more common in male and benign diseases were more common in females.  Benign conditions were more common in younger age group than malignant conditions which were more common in older age group. Nephrectomies in malignant conditions had a higher rate of complications than benign conditions. One patient in malignant group died in immediate postoperative period and one patient of benign group died in early postoperative period (<7 days) with overall 30 days mortality rate was 1.89%.

In our study nephrectomies were performed more in malignant diseases than benign diseases. The mean age of patients undergoing nephrectomies for benign conditions were relatively younger than the mean age of patient undergoing nephrectomies with malignant tumours. There was a higher rate of post-operative complications in malignant tumours than benign diseases but there was no difference in overall mortality.
Prevalence of hypertensive retinopathy among the known diabetics in a community-based setting using a non-mydriatic fundus camera
Authors: Hansdak Amod , Rajaram Sarayna , Ariarathinam Newtonraj , Natesan Murugan , Bazroy Joy , Purty Anil Jacob
Published: November 2022

Hypertension is a leading cause of morbidity and mortality and is associated with the risk of cardiovascular, cerebrovascular disease, and target organ damage. The risk increases exponentially in individuals with diabetes. Hypertensive retinopathy is a marker for target organ damage, so screening for hypertensive retinopathy helps in cardiovascular risk stratification. This study was conducted with an objective to screen for hypertensive retinopathy among known diabetics using a portable non-mydriatic fundus camera to ascertain its prevalence.

The study was conducted in three selected field practice areas of the Department of Community Medicine. A house-to-house survey was performed using a predesigned, pretested questionnaire among 302 known diabetics. The study participants were subjected to visual acuity examination using Snellen's chart and retinal fundus examination using a portable non-mydriatic Bosch Mobile Eye Care Solutions fundus camera. The fundus images were transferred to a laptop and were reviewed and graded by an experienced Ophthalmologist.

Among the 302 participants studied, 60 were diagnosed with hypertensive retinopathy. The prevalence of hypertensive retinopathy among diabetic patients was 19.9 % (95% CI: 15.7% - 24.6%). The prevalence was found to be higher in ** (21.8%; 95% CI: 16% - 28.6%) as compared to ** (17.5%; 95% CI: 11.8% - 24.6%).

Early detection of hypertensive retinopathy with cardiovascular risk stratification and initiation of prompt treatment among the high-risk individuals will help reduce the morbidity caused due to end-organ damage and premature mortality to a greater extent and will pave the way forward to achieving sustainable developmental goals.
Dengue hemorrhagic fever and bradycardia
Authors: Wagh Prashant S. , Kashyape Subhash , Wagh Swati P.
Published: November 2022

The numbers of patients with dengue fever are increasing in the world and affecting the health of society. Overcrowding urbanization and increase in travelling are having a direct impact on the improvement in the numbers of patients. The causes of relative bradycardia like Hypothyriodism, Electrolyte imbalance and structural heart disease were also having a significant impact on the health of the human. The relative importance of immune and neural mechanisms and also any direct cardiac pathology in the aetiology of dengue associated with relative bradycardia.

The researcher was conducted from July 2018 to December 2020. The researcher has selected the sample size of 100 patients from tertiary care hospital which was attached to the research institution. Most of the patients were having a history of fever and symptoms like vomiting, joint pain, diarrhoea, abdominal pain and headache.

The analysis of collected data of patients shows that 98 people were having a high fever, 43 were facing issues related to vomiting, 11 patients were having malaise and 12 patients were having body ache. These symptoms have shown that dengue is affecting health and leading to relative bradycardia. The lack of treatment and delay in the care services and support can be life-threatening for the patients.

The relative bradycardia is a notable feature among the patients of dengue and affecting the respiratory and heart rate of the patients. However, this condition is reported among the positive dengue IgM/NS patients. The proper investigation of the relative bradycardia situation among the patients is beneficial for the care professional to identify the method of treatment and providing clinical care.
Prospective study of acute illness observational scale in children of age 2 months to 5 years with respiratory illness, its corelation with radiological findings prognosis and who grading of ARI in inpatients of teritiary care hospital
Authors: Siromani Sikha Maria , Borigama Naveen Kumar , Swetha Mangalagiri
Published: November 2022

: In children under the age of five, acute respiratory illness (ARI) is the leading cause of preventable mortality. For the early detection of seriousness and

In the current study, timely treatment of ARI Acute illness observation scale (AIOS) an illness severity was used.

To study correlation of AIOS with WHO grading of pneumonia, radiological findings and prognosis in children of age 2 months to 5years.

A two-month hospital-based prospective observational research was done on 80 children aged 2 to 59 months who were admitted to the hospital with pneumonia throughout the study period.

: The association between AIOS score versus WHO grading ( severity) was statistically significant with P value of <0.0000001. There is a linear positive relationship between the AIOS score and WHO grading (severity the association between AIOS score and WHO grading (severity) is statistically significant with P value of <0.00001. There is a linear positive relationship between the AIOS score and duration of hospital stay. The association between AIOS score and duration of hospital stay is statistically significant with P value of <0.00001. The mean AIOS score at the time of admission was greater in cases which died than the cases which were discharged.

AIOS scoring is useful in anticipate abnormal x-ray findings in acute respiratory illness in 2-59 months old children.
Clinical study of branch retinal vein occlusion (BRVO) in a tertiary eye care center
Authors: Swain Suresh Chandra , Parida Subhabrata , Sethy Shubham
Published: November 2022

Branch Retinal Vein Occlusion (BRVO) is a common retinal vascular disorder which involves one of the branch retinal veins. The aim of the study is to analyse epidemiology, risk factors, clinical characteristics in the distribution of different types of BRVO and final visual outcome after treatment and six months follow up.

This is a prospective study including 222 patients of BRVO was done from October-2018 to September-2020. Clinical evalution included, detailed history with systemic risk factors, visual acuity testing, Slit-lamp biomicroscopy, Intra occular pressure, detailed fundus evaluation, fundus fluorescein angiography, Optical Coherence Tomography and Gonioscopy. Laboratory test included complete blood count, Erythrocyte sedimention rate, fasting blood sugar, serum lipid profile. Treatment given, observation and follow up, intravitreal (lV) ranibizumab, IV triamcinolone and laser photo coagulation.

Out of 222 BRVO patients, 207 (94.1%) were major BRVO (129(58.1%) were suprotemporal BRVO, 66(29.8%) were inferotemporal BRVO) and 15 (5.9%) were macular BRVO. Maximum number of patients 108 (48.6%) in the age group of 61-70 years. Male patients 126 (56.7%) more than females 96 (43.3%). Right eye 117 cases (52.7%) were involved slight more than the left eye 102 cases (45.9%). Blurring of vision 162 (72.9%) is the commonest symptom. Hypertensive patients 113 (50.9%) affected more followed by Diabetic 36 (16.2%) and cardiovascular disease 33 (14.9%). Mean Systolic blood pressure (SBP), Diastolic blood pressure (DBP), ESR & Fasting blood sugar (FBS) are higher in Macular BRVO, cholesterol level is higher in Major BRVO. Retinal haemorrhage was present in all cases. Macular edema was present in 87.4% of patients in whom OCT was done. At the end of six months after treatment in majority of patients i:e 85.1% had BCVA between 6/6-6/18. There was dramatical improvement of vision after receiving intravitreal Ranibizumab (P value 0.041).

There is strong association of conventional risk factors with BRVO. Visual prognosis depends on initial status with careful monitoring for macular ischaemia, macular edema, development of neovascularization and subsequent neovascular glaucoma followed by appropriate therapy like IV Ranibizumab, IV Triamcinolone and laser photocoagulation etc wherever required. There is dramatical improvement of vision after receiving intravitreal Ranibizumab (P value 0.041).
Covid 19 pandemic-lockdown and its psychological effects on children age group 4 to 10 years, a cross-sectional study from a school in Central India
Authors: Pazare Pradeep , Bansode Swapnali , Khobragade Roopal
Published: November 2022

This study will provide an insight into the psychological impact of lockdown on young children.

The current study is a questionnaire-based cross-sectional study. The research was done among parents of children ranging in age from 4 to 10 years old who attend various schools in Nagpur city. The research ran from March 2021 to August 2021, for a total of six months. The study enlisted the participation of parents of kids aged 4 to 10 years old.

Sadness significant, found that children of both working parents are significantly sad as compared to non-working or only any 1 parent working (p= o.008). Also, children who are using smartphones for <2hours for playing games are significantly sad than others. (p=0.001). Aggressiveness was significantly (p= 0.002). Children of <7 years are significantly more aggressive than >7years. Anxiety was significantly more among females compared to male children (p=0.03). Also, children belonging to single parents and joint families were significantly more anxious compared to nuclear families (p=0.04).

The lockdown due to the Covid-19 pandemic has caused profound psychological effects and has increased the rates of depression, anxiety, sadness, and aggressiveness in children.
Successful pregnancy in a patient via holistic approach of Uni5 based treatment with recurrent implantation failure: A case report of unexplained infertility
Authors: Chhalliyil Pradheep , Nandini Usha , Thota Neelima
Published: November 2022

In this study, a case of a 22-year-old married woman with a clinical history of Polycystic Ovary Syndrome (PCOS), recurrent implantation failure was reported and was subsequently diagnosed with adenomyosis. Concurrent symptoms of uterine fibroids or polyps were noted. Meanwhile, the patient had undergone In vitro fertilization (IVF) twice, which was unsuccessful and after that, she neither took any treatment nor was under any medications for almost 3 years. Then the patient and her husband followed the Uni5 treatment regimen for six months and she was medically confirmed as pregnant in August 2017 in the same hospital, where she had previously undergone the IVF procedure. She later gave birth to a healthy baby weighing around two kgs during her 36th week of pregnancy. This case report concludes that the Uni5 treatment regimen can be considered as a holistic, safe, promising, and cost-effective alternative method of treatment for patients who have failed to conceive even after receiving In vitro fertilization (IVF) and Intrauterine Insemination (IUI) treatments and for those who cannot afford such expensive treatment procedures.
Geltung der Werte beim gestalten sozialer Relationen im Kontext ausgewählter Entitäten der Ethik von Max Scheler. Eine philosophische Skizze mit Blick auf die Migrationsproblematik
Authors: Rynkiewicz Kazimierz
Published: November 2022

Der Aufsatz befasst sich mit der Wertproblematik bei Max Scheler, rückblickend auf den Begriff „Sympathie“ im Kontext der Migrationsfrage. Dabei werden zunächst die Phänomene wie Mitgefühl und Liebe aufgegriffen, deren hermeneutische und phänomenologische Relevanz personal fundiert sind. Damit der Begriff der Person seine eigentliche Dynamik in der realen Welt entfalten kann, müsse er allerdings die Rahmenbedingungen der materialen Wertethik Schelers transzendieren, deren Anliegen auf dem apriorischen Fundament erscheint. Zu dem Zweck wird der Begriff „Suppositum“ von Karol Wojtyla herangezogen, der die Person als Subjekt des Existierens und Handelns zum Vorschein bringt. So wird nicht nur die gesellschaftliche Harmonie real gefördert, sondern auch die personale Ordnung aus ethisch-anthropologischer Sicht verfeinert. Dies wirkt sich letzten Endes auf den Umgang mit der Migranten- bzw. Flüchtlingsfrage aus.
Implementing Nature’s Rights in Colombia: The Atrato and Amazon Experiences
Authors: Richardson Whitney , Bustos Camila
Published: November 2022

Los enfoques de los derechos de la naturaleza se están desarrollando como un medio legal alternativo para permitir la justicia para la naturaleza y, a menudo, también para los humanos. Este estudio examina los dos enfoques fundamentales de los derechos de la naturaleza ordenados por los tribunales de Colombia que reconocen los ecosistemas, la cuenca del río Atrato (2016) y la Amazonía colombiana (2018), como un sujeto legal con derechos de protección, mantenimiento, conservación y restauración. Desarrollados como remedios para las violaciones de los derechos humanos, ambos casos ofrecen oportunidades para explorar variaciones en los enfoques de los derechos de la naturaleza y la relación entre los esfuerzos para hacer posible la justicia para los humanos y la naturaleza. Nos basamos en el compromiso académico existente con los casos al contribuir con un estudio de archivo detallado sobre su implementación, complementado con algunas entrevistas con actores clave, así como al evaluar la implementación de los fallos utilizando marcos de justicia ambiental y ecológica para determinar hasta qué punto. han permitido la justicia para los humanos y la naturaleza hasta la fecha. Argumentamos que los enfoques de los derechos de la naturaleza de la cuenca del río Atrato y la Amazonía colombiana actualmente no alcanzan sus objetivos de permitir la justicia tanto para los humanos como para la naturaleza. Hasta el momento, la interpretación y la implementación de las sentencias aún no han hecho posible la justicia y, en algunos casos, han perpetuado las injusticias. de las sentencias aún no han hecho posible la justicia y, en algunos casos, han perpetuado las injusticias.
A case of rare development of arteriovenous malformation of the lower lobe of the right lung
Authors: Nikonenko A. M. , Kulchitskaya N. S. , Golubeva A. V. , Il’ina I. V.
Published: November 2022

Arteriovenous malformations are one of the variants of congenital vascular malformations resulting from a defect in the development of the arterial and venous systems with the formation of direct messages between vessels of different diameters and shunting of blood with high velocity characteristics from the arterial to the venous part of the vascular system. Arteriovenous malformations are characterized by a wide variety of clinical manifestations and in some cases may be accompanied by severe circulatory disorders. Arteriovenous lung malformation (AVML) accounts for a small fraction of the AVM structure. The defect consists in the presence of arteriovenous anastomoses at the level of segmental, subsegmental and smaller vascular divisions. This article presents a case of detection of a rare malformation of arteriovenous malformation of the lower lobe of the right lung.
Wajah Pendidikan Islam Persfektif Islam Humanis dan Virtualis
Authors: Karim Syakban abdul
Published: November 2022

Islamic education focuses on civilized moral and intellectual education with the concepts of tarbiyyah, ta'lim, and ta'dib. For this reason, this article examines the face of Islamic education from the perspective of Humanist and virtual Islam by using a literature review research method. Islamic education is not only to ensure happiness in fulfilling the needs in the world but also in the hereafter. Good nature and character and have good morals who are always updating themselves. be a reference of humanist Islam. Humanist and virtual Islam in Islamic education is embodied in learning behavior that is practiced with love so that all its potential develops in an education system based on the Qur'an and As-Sunnah. Islamic education in the virtualist perspective is the crystallization of Islamic adherents of religious values ??in the development of cyberspace. Virtualist Islam is shown by the behavior of the sami'na towards the teachings conveyed through online da'wah. So that religious fanaticism depends on who is portrayed and the choices of Islamic studies in cyberspace. In essence, Islamic education from a humanist and virtualist perspective is an education system that is taught with love through real and virtual interactions.
Hubungan Asupan Makronutrien, Aktivitas Fisik, dan Status Gizi dengan Usia Menarche Pada Remaja Perempuan Usia 9-15 Tahun di Desa Kedunglosari Kabupaten Jombang
Authors: Tri Sutanti Puji Hartati  , Farapti Farapti  , Emyr Reisha Isaura
Published: November 2022

Background: Menarche is the first menstruation experienced by adolescent girls. The age of menarche in Indonesia has decreased from 13 years in 2010 to 12.4 years in 2018. The age of menarche is influenced by internal and external factors, some of the factors are macronutrient intake, physical activity, and nutritional status. The decrease in age at menarche is associated with an increased likelihood of uterine myoma, dysmenorrhea, and breast cancer.
Objectives: To analyze the relationship between macronutrient intake, physical activity, nutritional status and age at menarche in adolescents Girl 9-15 years old.
Methods: This research used cross sectional design with sample size of 87 adolescent girls who had experienced menstruation and selected using simple random sampling. Data were collected by macronutrient intake used Semi-Food Frequency Questionnaire (SQFFQ),  physical activity used Short Form International Physical Activity Questionnaire (SF-IPAQ), anthropometric data to assess nutritional status through measurement of body weight and height and age of menarche used a self-report questionnaire. Data was analyzed by t-test, chi-square and linear regression with 95% confidence level.
Result: There was a significant relationship between fat intake (­p = 0,049) and nutritional status (β = -0.92, p <0.001) with the age of menarche. The results of the analysis showed that there was no significant relationship between energy intake (p = 0,058), protein intake (p = 0,178), carbohydrate intake (p = 0,099), and physical activity (p = 0,422) with age at menarche.
Conclusions: fat intake and nutritional status during adolescence is related to the age of menarche. Prevention for cancer in women should be carried out as early as possible when adolescent girls have not menarche. One of prevention is managing the nutritional status of adolescent girls by paying attention to diet.
Keywords: nutritional status, macronutrient intake, physical activity, age at menarche, adolescent girls
Complex upper extremity injuries: targeted muscle reinnervation, free functional muscle transfer, and vascularized composite allotransplantation
Authors: Bekisz Jonathan , Hacquebord Jacques H.
Published: November 2022

Restoration of upper extremity function poses a unique surgical challenge. With considerations ranging from ensuring appropriate skeletal support and musculotendinous and ligamentous anatomy, restoring adequate vascularity and innervation, and providing sufficient soft tissue coverage, upper extremity injuries present a diverse range of reconstructive problems. Recent history has been marked by an expansion of novel techniques for addressing these complex issues. Sophisticated modalities, such as targeted muscle reinnervation, free functional muscle transfer, and vascularized composite allotransplantation, have become some of the most powerful tools in the armamentarium of the reconstructive surgeon. This review article aims to define the distinguishing features of each of these modalities and reviews some of their unique advantages and limitations.
Using a modified rabies immunoglobulin protocol in a crisis of unavailability: Ethical and practical challenges
Authors: Bharti Omesh Kumar
Published: November 2022

Rabies is a dreaded disease of zoonotic origin, responsible for an estimated 55,000 deaths annually, of which 20,000 deaths are in India. Some animal bite patients need rabies immunoglobulin (RIG) for post exposure prophylaxis, in addition to the vaccine against rabies. The major reason for the high death rate in India is the high cost of RIG. Until 2017, the WHO-recommended protocol required a large amount of RIG. I describe how a cost-saving protocol for RIG was implemented in Himachal Pradesh. The published results contributed to the modification of the WHO’s global recommendations on RIG use.
ANALISIS PENGARUH LITERASI KEUANGAN TERHADAP MINAT INVESTASI CASH WAQF LINKED SUKUK PADA GEN Z
Authors:   Prodi Ekonomi Islam, Fakultas Ilmu Agama Islam, Universitas Islam Indonesia Yogyakarta, Sheila Pinasti Ulfi , Achiria Siti ,   Prodi Ekonomi Islam, Fakultas Ilmu Agama Islam, Universitas Islam Indonesia Yogyakarta
Published: November 2022

Penerbitan CWLS (Cash waqf linked sukuk) merupakan salah satu bentuk komitmen pemerintah untuk mendukung pengembangan investasi sosial dan pengembangan wakaf produktif di Indonesia. Minat masyarakat terhadap CWLS terus meningkat. Akan tetapi, partisipasi generasi z pada investasi CWLS masih rendah. Hal ini dibuktikan dengan tidak adanya wakif generasi z yang memesan SWR002. Padahal pada penjualan CWLS Ritel seri SWR00, partisipasi wakif pada generasi z dengan pemesanan Rp 9 juta dan wakif sejumlah 4 orang. Salah satu penyebab rendahnya partisipasi generasi z pada investasi CWLS dapat dikorelasikan dengan masih rendahnya literasi keuangan tentang CWLS. Penelitian ini bertujuan untuk mengetahui pengaruh literasi keuangan terhadap minat investasi CWLS pada gen z. Data penelitian ini menggunakan data primer yang disebarkan melalui google form kepada 100 responden dengan kriteria mahasiswa di Yogyakarta yang mengetahui wakaf dan belum pernah berinvestasi CWLS. Pengambilan data dilakukan dalam kurun waktu bulan Mei-Juni 2022. Penelitian ini menggunakan teknik purposive sampling dalam pengambilan sampelnya. Penelitian ini berjenis kuantitatif dengan metode analisis data regresi sederhana yang menggunakan software SPSS versi 25. Hasil penelitian ini menunjukkan bahwa variabel literasi keuangan berpengaruh positif signifikan terhadap minat investasi cash waqf linked sukuk (Y). Serta secara simultan literasi keuangan (X) berpengaruh positif signifikan terhadap minat investasi cash waqf linked sukuk (Y). Variabel independen berkontribusi mempengaruhi variabel dependen sebesar 33% sedangkan sisanya 67% dipengaruhi oleh variabel lain di luar model. Kata Kunci: Literasi Keuangan, Minat Investasi, CWLS, Generasi Z
Managing the Pandemic in the South Asian (SAARC) Countries
Authors: Pulla Venkat Rao , Shoukat Aisha , Jafar Muhammad , Alam Md. Fakhrul , Attanayak M.T.R. Shamini , Mussarat Jabeen , Gautam Gyanendra , Lafain Rachel , Prasad Sanjay
Published: November 2022

This paper explores the coronavirus pandemic response from a South Asian perspective. When their case numbers were still relatively low, the South Asian Association for Regional Cooperation (SAARC) countries adopted lockdowns at the same time or before India did. On 24 March 2020, when there were just two confirmed cases, Nepal went into lockdown, and Sri Lanka locked down on 22 March, when there were 78 cases. India locked down the day after Nepal, with all countries imposing some form of restrictions on people’s movement. This paper draws its data from the first year of the pandemic that loomed in the SAARC nations. The regional cooperation provided by SAARC has allowed the sharing of resources and a strengthening of the region’s self-reliance. Notably, the commitment made by India to ensure its neighbours are supplied with vaccines, many of these donated. The eight-member SAARC states are Afghanistan, Bangladesh, Bhutan, India, Maldives, Nepal, Pakistan, and Sri Lanka.
This paper draws on the knowledge and perceptions of academics and social workers in the SAARC countries. It provides insight into the responses, impacts, vulnerabilities, and challenges faced by the region and in each specific country since the beginning of COVID-19. This paper also offers a discussion on vaccines, PPE, as well as the role of cooperation across the region. The relationship between India and the SAARC countries and its ‘neighbourhood first’ policy are also discussed.
On evaluation of the solution of Gaussian impulse propagation
Authors: Bakhvalov Pavel Alexeevich
Published: November 2022

We consider the solution of the 2D wave equation with the initial data prescribing a Gaussian pulse. This solution has integral representations. Previously proposed algorithm of its evaluation is optimized by the use of more precise error bounds of numerical quadratures.
Aplikasi Penggunaan Alat Pengering Pengganti Oven untuk Pembuatan Herbarium di Kebun Raya Liwa Kabupaten Lampung Barat
Authors: Yulianty  , Amir supriyanto  , Eti Ernawiati  , Lili Chrisnawati
Published: November 2022

One of the countries with high biodiversity is Indonesia. The potential of existing plants has not been maximally empowered by the community, especially in the Liwa Botanical Gardens. The involvement of the staff in the KRL is very necessary to be able to directly collect the observed plants and make a herbarium. Constraint faced in making herbarium is in the drying process. So far, the herbarium drying process is still being carried out in Department of Biology, University of Lampung. This PKM activity will begin with a pre-test to determine the initial ability of KRL staff on the importance of the drying process and  the practice of making simple herbarium dryers instead of ovens. At the end of the activity, KRL staff were given a post-test to determine the increase in knowledge about the importance of drying herbariums. With this PKM activity, KRL staff increase their knowledge and skills in using simple tools for drying plant samples and in the long term the availability of more diverse herbariums in an effort to conserve potential plants in KRL. The result of this activity was an increase in score points by 28.08 and a percentage increase in knowledge of 51.63%.
Lives at Risk: A study of girls dropping out of school in Juba, Rumbek and Pibor Counties, South Sudan
Authors: Lillian Rutandaro Sherrie , Lundambuyu Munalula Christine , Otuta Rogers , Mangundu Manenji
Published: November 2022

This study was undertaken by Oxfam in three South Sudanse counties as part of the SIDA-funded project 'Building Resilience through Gender and Conflict-Sensitive Approaches to Education, Skills Development, and Sustainable Livelihoods'. Its purpose was to shed light on why so many girls drop out of school. The research revealed that women and girls often lack decision-making power over their lives. Early or forced marriage, the abduction of girls, perceptions that education delays marriage – and that educated girls risk not finding husbands – all contribute to dropout rates. Additional challenges include a lack of adequate hygiene and sanitation facilities in schools, the distances learners need to travel, insecurity caused by communal violence, floods, food insecurity, and a heavy household work burden. The Government of South Sudan has in place laws and policies to address these issues, but they remain largely on paper and enforcement mechanisms are weak. The report analyses each of these factors in turn and presents recommendations for how the SIDA project can begin to address them in its future programming.
Industrial Organization of the Maritime Seismic Acquisition Market
Authors: Junior Paulo Roberto de Melo Barros , Ferreira Hamilton , Lemos Mauro
Published: November 2022

In this article, we analyze the industrial organization of the Maritime Seismic Acquisition Market (MSAM). Firms in this market are process, science, and technology-intensive and provide critical geophysical information for oil companies operating in the upstream offshore segment. We aim to find the determinants of price and cost changes and their relationships with market structures, firms conduct, and performance (SCP), considering the effect of oil price volatility on MSAM demand. To achieve this objective, we use a theoretical framework of Industrial Organization (IO) to analyze the empirical data of MSAM at a global database between 2006 and 2019. Our work is structured to estimate SCP and the New Empirical IO (NEIO) parameters related to concentration, market power, and competition and verify the hypothesis about market power or collusion from empirical demand and cost models. We found that concentration levels and profits in MSAM firms decrease to any demand increase. These concentration and profit fluctuations occur because market-fringe firms generate competitive pressure on the industry's average costs, an essential factor explaining price increases during market heating periods. Although MSAM has a sizeable concentration level, its firms have low levels of market power and markups with a high degree of competition, which is typical of a Competitive Oligopoly.
Relationship between Internet Addiction and Obesity and the Predictive Role of Emotion Dysregulation
Authors: Azizi Morteza , Abbasi Behrouz , Aghaei Hajar
Published: November 2022

Background: In recent decades, with the significant developments in technology, the Internet has become a main part of peoples' lives. The widespread use of the Internet has raised significant concerns about problematic Internet behaviors and their consequences. This study aimed to examine if Internet addiction significantly predicts obesity and whether Internet addiction and obesity are significantly predicted by emotion dysregulation.
Mthods: 367 school-attending adolescents (M age = 13.35; SD = 0.82; 49% girls) in Tekab were recruited and completed the Difficulties in Emotion Regulation Scale (DERS) and Internet Addiction Test (IAT) measures, while their BMI scores were calculated to examine the participants' obesity levels.
Results: The results indicated that Internet addiction significantly predicted obesity, while they both were significantly predicted by emotion dysregulations.
Conclusion: Our findings could be informative for clinicians working with individuals suffering from Internet addiction and obesity.
Differences in the Seoi-Nage Skill between Eite and Non-Elite Judo Players
Authors: Choi Sang-Hyup , Song Yong-Gwan
Published: November 2022

Seoi-nage skill is one of the most frequently used skills in judo matches and comprises three phases, namely unbalancing, positioning, and throwing. It is necessary to understand the kinematic characteristics of the three phases to provide helpful feedback for learning and guiding seoi-nage skills. We aimed to investigate the kinematics of each phase using a judo throw device and a three-dimensional motion capture camera system. On comparing the performances of elite and amateur (non-elite) judo players (10 each), the rotation and tilt angle characteristics of the shoulder, pelvis, and hip and knee joint flexion-extension angle were better in the elite group. Our findings indicate that kinematic variables determine the effective performance of seoi-nage. The center of gravity of the opponent gets lifted (unbalancing), following which the body moves forward to the opponent (positioning). It must pull the opponent to the end such that they can throw it down (throw). While the rate of change in the vertical direction should be significant, that in the horizontal direction should be low to pull the opponent sufficiently toward the attacker’s body. In addition, the shoulder and pelvis should be rotated together while maintaining the extension of the hip and knee joints to achieve effective sedation.
Analysis of georadar responses on environmentally significant karst landform
Authors: Gao Qiangshan , Hussain Yawar , Yang Tianchun
Published: November 2022

Peak-cluster depression (PCD) is a typical karst landform and a crucial aspect in non-invasive geophysical evaluation of the environmental concerns of the karst desertification regions (i.e., canopy growths, animal habitat, among others) related with karstification and its soil stocks and their moisture contents. To that end, a promising non-invasion, less labour-intensive and cost-prohibited geophysical technique (georadar/GPR) being limited in its operations because of the tilt signals and loss of information introduced by the uneven topography of PCD. Therefore, it requires a detailed investigation applying numerical analysis (considering karst topography and soil conductivity) implicating in a case study which is the scope of the present work. The findings of numerical analysis showed that under moderate soil conductivity conditions, the tilt signals could contain the reflections from both surrounding hills and subsurface inclined interfaces. The data processing workflows include the F-K filtering to remove or suppress the tilt signals. Then we applied the attribute analysis as additional information to aid in interpreting soil depth in depression. The soil depth obtained from the auger showed results highly consistent with that of the GPR findings. It is concluded that the application potential of GPR for the karst peak-cluster depression study is moderate to the fact that inferred information can partly be utilised while the rest is mixed or contaminated with other irrelevant information.
An Online and Highly-Scalable Streaming Platform for Filtering Trolls with Transfer Learning
Authors: Lai Chun-Ming , Chang Ting-Wei , Yang Chao-Tung
Published: November 2022

Society nowadays is provided with a maturely developed internet, and On-line Social Media (OSM) such as Twitter and Facebook are one of the vital communication channels for information exchange and public affairs discussion. Unfortunately , due to anonymity and trolls, improper statement or content are corroding these OSM platforms and their users. Current defense methods for inappropriate information are based on offline (semi)-manual assessments and fail to take into account that OSM feeds are online data streams. In this paper, we implement a robust and decoupled system considering social media data as streaming data. With Publisher and Consumer model, our system can process more than 179 MB per second with only 166.3 ms latency using Apache Kafka. Accordingly, we deploy a well-trained transfer learning model to classify incoming data streams with an accuracy of 0.836. It’s our hope that the proposed architecture can help the community to build a more constructive and flawless OSM platforms.
Some Immunological characters in Women with Celiac Disease from Thi-Qar province - South of Iraq
Authors: Abdullah Safaa Hussein , Al-Badran Adnan Issa
Published: November 2022

Background
Celiac disease is a chronic small intestinal inflammatory disease characterized by a lifelong reaction to dietary gluten in individuals with genetic predisposed. Many studies were suggests the presence of celiac disease predominance in woman than man patients. This study was conducted in Thi-Qar province and the blood samples were collected from healthy and celiac patients whose diagnosed by serology tests using Enzyme Linkage Immuno Sorbent Assay. The current study was designed to demonstrate women's serologic parameters and their characters in Thi-Qar province.
Results
This case-control study demonstrates that women are predominance to incidence with celiac disease and the Anti-tissue transglutaminase IgG is the best and quite accurate test than other tests used in diagnostic approach.
Conclusions
This study detects that women are more susceptible to incidence with CD and using the two steps testing is a quite precise strategy for the diagnosis of suspicious persons and can be a potent marker for monitoring the activity of celiac disease.
An Expectation-Maximization approach for matrix factorization in location-based recommender systems
Authors: Moayedikia Alireza
Published: November 2022

On Location Based Social Network (LBSN) platforms, users benefit from location recommendation algorithms to find places of interest. Several algorithms have been proposed to accomplish the location recommendation task. However, these algorithms suffer from (i) the lack of trust information consideration and (ii) assuming users’ interest are static and does not change overtime. To overcome these two shortcomings this paper introduces an adaptive probabilistic-based location recommendation algorithm known as EXMAX which uses expectation-maximisation along with matrix factorisation to predict the rating a user may give to the next visit. The predicted rating will be used as a filter to remove any places with a score lower than the user’s predicted rating. EXMAX represents check-in data as a user-location matrix where every time a user checks into a new location check-in along with location information will be appended to the user-location matrix. This representation method ensures EXMAX preserves the most up-to-date users’ preference information. Also, the proposed algorithm exploits friendship network data as well as sentiment of the comments left by the user to label every checkin with either a positive or negative experience. To measure EXMAX efficacy, its performance is tested in several experimentation scenarios and compared against three rival algorithms in terms of root mean square error and Yelp dataset. The results confirm EXMAX robustness and superiority over other probabilistic and statistic location recommendation algorithms.
Identification of Potent and Novel Inhibitors against Dual specificity mitogen-activated protein kinase kinase 1 (MEK1)
Authors: Madhukar Geet , Kumari Sangeeta , Rath Pragyan Parimita , Gourinath Samudrala , Mondal Neelima , Subbarao Naidu
Published: November 2022

Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer, globally. Its high mortality rates hasn’t changed much in the last three decades and the overall survival is still less than 5 years. Therefore, there is an urgent need for novel therapeutics specifically developed for HNSCC. One of the most commonly altered oncogenic pathways is Ras-Raf-MEK-ERK signalling pathway. This pathway is downstream to EGFR and has been reported to be involved in radio resistance. MEK1 is a tyrosine/threonine protein kinase found in the MAP kinase (MAPK) signalling cascade which is constitutively expressed in approximately 30% of all the cancer types. It holds a very strategic position in the MAPK cascade. It is the only kinase which activates ERK ½ which is involved in several cellular pathways, both cytoplasmic as well as nuclear and has been found mutated in various cancers including HNSCC. Currently, there is no FDA approved inhibitor of MEK1 specifically against HNSCC. Therefore, designing more effective and specific MEK1 inhibitors could be a promising strategy in the treatment of HNSCC. We screened more than 400,000 compounds to select the two best candidate compounds, C387-1559 and G545-0469 using High Throughput Screening (HTS) of huge databases (National Cancer Institute (NCI), Life Chemicals, Chem Diversity and ChEMBL), and Molecular Dynamic Simulations. Both the selected compounds were further analysed at different concentrations by Biolayer Interferometry (BLI) technique for their real-time interaction with the MEK1 protein. The selected compounds were evaluated for their cytotoxic effect against different cancer cell lines. The IC50 values of the compounds C387-1559 and G545-0469 on human tongue squamous cell carcinoma cell line, CAL27, were 5µM and 6µM, respectively and on human prostate cancer cell line, DU145, were 14.77 µM, 54.38 µM, respectively at 72hrs. This data suggests higher efficiency of C387-1559 and G545-0469 on human head and neck squamous cell cancer than human prostate cancer. Overall, this study identified two novel inhibitors of MEK1 that can be used in the development of potential therapeutics against HNSCC.
Investigation on reachable domain of contingency return trajectories in the circumlunar flight phase based on interval analysis
Authors: Lu Lin , Zhou Jianping , Li Haiyang , Zhang Hailian
Published: November 2022

The investigation on reachable domain based on interval analysis is performed, which is aimed for the contingency return trajectories during the circumlunar flight stage for manned lunar landing engineering. First, the issue of contingency return trajectory which adopts a non-coplanar maneuver during the circumlunar flight phase is described. The mathematics model of the reachable domain of contingency return trajectories is established. Second, the contingency return trajectory is designed. An improved interval branch and bound algorithm is introduced and a reachable domain calculation method of the contingency return trajectories is proposed. Third, in numerical simulations, by comparing the reachable domain obtained by the traditional brute force method, the accuracy of the method presented in this paper is verified. It also indicates that this method has a higher calculation efficiency. Finally, abundant simulations are performed to discuss the parameter characteristic of reachable domain by adopting this method. The study conclusions can serve as an important reference for the selection and decision of contingency return trajectory plans in the future manned lunar landing engineering.
Link fusion algorithm based on wavelet multi-resolution analysis
Authors: Wang Xiang , Dong Shaowu , Song Huijie , Sun Baoqi , Wu Wenjun , Wang Weixiong , Guo Dong , Gao Zhe
Published: November 2022

The performance characteristics of various time transfer links vary. TWSTFT (Two Way Satellite Time and Frequency Transfer) links have excellent long-term stability, but when compared to the GNSS PPP link, the short-term fluctuations are significant, and the measurement results clearly show a diurnal trend. The short-term stability of GNSS (Global Navigation Satellite System) PPP (Precise Point Positioning Solutions) links is strong, but long-term stability comparative to the TWSTFT link is poor because of boundary effects in the data processing. You may fully take advantage of links to increase time transfer accuracy and stability by fusing data from different types of links. The time-frequency domain is used in combination with the wavelet data analysis technique. Its capacity to decompose the original data into various related signals at various sample rates as necessary defines it. Processing TWSTFT and GNSS PPP links data at various sampling rates is feasible using the concept of multi-resolution decomposition. In this article, a multi-resolution data fusion technique based on wavelet transformation is attempted. The model-based dynamic system analysis approach and the statistical properties-based multi-resolution signal transformation method are combined using multi-resolution analysis concepts to establish the goal state observation data. The differences in data sampling intervals between TWSTFT and GNSS PPP links can be eliminated by the multi-resolution data fusion estimation algorithm. The original data is first transformed into a series of wavelets based on the time division, frequency division and multi-resolution properties of wavelet transform. then using Kalman filtering estimation on each scale, and finally the wavelet transform's Mallat rapid reconstruction method is applied to combine the results. This approach can be used to estimate the time transfer links using links fusion data from several different sampling rates. Processed and analyzed are the TWSTFT and GPS PPP time transfer link results between the Physikalisch-Technische Bundesanstalt (PTB) and the National Time Service Center (NTSC) of the Chinese Academy of Sciences. The findings demonstrate that the fusion algorithm is able to enhance the link's stability on a whole, particularly the short-term stability, which has increased markedly within 6 hours on average. Additionally, it can reduce "Day-Boundary discontinuities" and aberrant connection interruptions on GPS PPP links to increase the resilience and reliability of links.
Accurate Estimation of the Boltzmann Factor
Authors: Bharathraj Goddalehundi
Published: November 2022

The probability of finding gas (monoatomic) particles at different energy levels based on the Boltzmann factor only crudely corresponds with the actual tabulated values using permutations. We derive an accurate expression for the probability using a more rigorous analysis. The partition determined by the new method is more evenly spread out than the partition determined by Boltzmann. Boltzmann method overestimates the probability at lower energy levels and underestimates at higher levels. The number of permutations implied by the new method is larger than Boltzmann method. Far from capturing the most probable combination, Boltzmann method fails to capture even the average case scenario. Also, Boltzmann method does not satisfy the energy conservation equation. It explains only 2/3rd or 2/fth portion of the total energy of the gas system at best.