bluuebunny/crossref_metadata_2025 huggingface dataset:
Radiology Departments as COVID-19 entry-door might improve healthcare efficacy and efficiency, and Emergency Department safety
Authors: Santos José María García , Martínez Juana María Plasencia , Ortega Pablo Fabuel , Ros Marina Lozano , Ayala María Carmen Sánchez , Hernández Gloria Pérez , Martínez Pedro Menchón
Published: September 2020

Background: Possible COVID-19 pneumonia (ppCOVID-19) patients generally overwhelmed EDs during the first COVID-19 wave. Home confinement and primary care phone follow-ups were the first-level regional policies for preventing EDs from collapsing. However, when ppCOVID-19 needed X-ray assessment, the traditional outpatient workflow at the radiology department (RD) was inefficient and raised concerns about potential interpersonal infections. We aimed to assess the efficiency of a primary care high-resolution radiology service (pcHRRS) for ppCOVID-19 in terms of time consumed at the hospital and decision reliability.Methods: We assessed 849 consecutive ppCOVID-19 patients, 418 appointed by general practitioners to the pcHRRS (home-confined ppCOVID-19 cases with negative –group-1- and positive -group-2- X-ray results) and 431 arriving at the ED by themselves (group-3). The pcHRRS provided X-rays and oximetry in an only-one-patient agenda for home-confined ppCOVID-19 patients. Radiologists made next-step decisions (group-1: pneumonia-, home-confinement follow-up; group-2: pneumonia+, ED assessment) according to X-ray results. ANOVA and Bonferroni correction, Student’s t-test, Kruskal-Wallis test, and Chi2 test were used to analyse changes in the ED workload, time-to-decision differences between groups, and pcHRRS performance for discriminating need for admission.Results: The pcHRRS halved ED respiratory patients (49.2%), allowed faster decisions (group-1 vs. home-discharged group-2 and group-3 patients: 0:41±1:05 h vs. 3:50±3:16 h; group-1 vs. all group-2 and group-3 patients: 0:41±1:05 h vs. 5:36±4:36 h; group-2 vs. group-3 admitted patients: 5:27±3:08 h vs. 7:42±5:02 h; P <0.001) and prompted admission in most cases (84/93, 90.3%).Conclusions: A Radiology Department pcHRRS may be a more efficient entry-door for ppCOVID-19 by decreasing ED patients and making expedited decisions while guaranteeing social distance.
Evaluating the interchangeability of infrared and digital devices with the traditional mercury thermometer in hospitalized pediatric patients: an observational study.
Authors: Dante Angelo , Gaxhja Elona , Masotta Vittorio , Cerra Carmen La , Caponnetto Valeria , Petrucci Cristina , Lancia Loreto
Published: September 2020

A gradual replacement of the mercury thermometers with alternative devices is ongoing around the world as effect of the global strategies to reduce mercury pollution. However, to reduce the risks of misdiagnosis, unnecessary treatments, and omission of care in the pediatric population, more evidence on the reliability and validity of alternative thermometers are needed. The aim of this comparative observational study was to detect any differences in temperature measurements between the gold-standard axillary mercury thermometer (AXLMER) and the alternative devices. Temperature values in Celsius (°C) were simultaneously measured in a group of Albanian children aged up to 14 years using both (AXLMER) and digital axillary thermometers (AXLDGT), as well as forehead and tympanic infra-red thermometers. The AXLDGT device, compared with the AXLMER, showed no clinically significant difference in the mean values (-0.04 ± 0.29 °C) and the narrowest 95% Level of Agreement (+0.53 °C to -0.62 °C) in the paired comparisons. For cut-off points of 37.0 °C and 37.5 °C, the AXLDGT showed the highest levels of sensitivity (67.4% and 72.5%) and specificity (95.3% and 99.1%) in detecting fever. This study indicates that the AXLDGT thermometer may prove the better option since it adequately balances accuracy, safety and children’s comfort.
The role of complementary feeding in India’s enigma of high child malnutrition rates: Findings from a comprehensive national study
Authors: Petrikova Ivica
Published: September 2020

Relative to its economic growth and poverty levels, Indian children suffer from higher levels of malnutrition than children in most other low- or lower-middle-income countries. The current Covid-19 pandemic is likely to further exacerbate the situation. Research presented in this article has examined the effects of infant and young child feeding practices on the rates of stunting, underweight, wasting, and anaemia amongst Indian children and concluded that feeding children between 6 and 23 months old (semi)solid food of sufficient variety, and particularly animal-source foods, has a significant positive effect on their nutritional outcomes. The study further assessed the effects of the Integrated Child Development Services and district-level livestock ownership on the helpful feeding practices and found that the Integrated Child Development Services encouraged beneficial dietary behaviour amongst children but did not improve their nutritional outcomes. In contract, district-level poultry ownership appeared to have both augmented the beneficial feeding practices and improved children’s nutritional outcomes.
Contexts and mechanisms that promote access to healthcare for populations experiencing homelessness: a realist review
Authors: Siersbaek Rikke , Ford John , Burke Sara , Cheallaigh Clíona Ní , Thomas Steve
Published: September 2020

Objective: The objective of this study was to identify and understand the health system contexts and mechanisms that allow for homeless populations to access appropriate healthcare when needed.Design: A realist review.Data sources: Ovid MEDLINE, embase.com, CINAHL, ASSIA and grey literature until April 2019. Eligibility criteria for selecting studies: The purpose of the review was to identify health system patterns which enable access to healthcare for people who experience homelessness. Peer reviewed articles were first identified through a systematic search, grey literature searching, citation tracking and expert recommendations. Studies meeting the inclusion criteria were assessed for rigour and relevance and coded to identify data relating to contexts, mechanisms and/or outcomes.Analysis: Inductive coding was used to generate Context-Mechanism-Outcome configurations which were refined and then used to build several iterations of the overarching programme theory.Results: Searching identified 330 review articles, of which 24 were included. Additional searching of grey literature yielded 50 records of which 12 were included. An additional 11 grey literature and primary sources were identified through citation tracking and expert recommendation for a total of 47 included sources. The analysis found that healthcare access for populations experiencing homelessness is improved when services are coordinated and delivered in a way that is organised around the person with a high degree of flexibility and a culture that rejects stigma generating trusting relationships between patients and staff/providers. Health systems should provide long-term, dependable funding for services to ensure sustainability and staff retention. Conclusions: With homelessness on the rise internationally, this study will inform health systems policy-making and implementation. It contributes to our understanding how healthcare systems can be more accessible for populations experiencing homelessness by providing long-term stable funding, promoting inclusive cultures and limiting stigma. Health systems should be flexible, timely and connected.
Cochlear Implant Rehabilitation During Covid-19 Pandemic: A Parents’ Perspective
Authors: Sahoo Lokanath , Kumari Abha , Patnaik Uma , Dwivedi Gunjan
Published: September 2020

Aim and Objectives: The current study was undertaken to assess the effect of Coronavirus disease 2019 (COVID-19) pandemic on cochlear implant rehabilitation of children with congenital non syndromic bilateral severe to profound sensorineural hearing loss (SNHL). The objectives were to find out the psychological impact of COVID-19 on parents of children with cochlear implant habilitation, to assess the performance of children with cochlear implant habilitation through tele therapy and to analyze the problems faced by the parents to obtain the professional hearing health care services for their cochlear implanted children.Material and Methods: An online questionnaire survey was conducted amongst the parents of children who had undergone cochlear implantation (CI) consequent to congenital severe to profound SNHL. Prior to COVID-19 pandemic, these children received regular auditory verbal therapy (AVT) including visits to the Centre for audiological services (mapping and troubleshooting of the speech processor).Results: The online questionnaire survey, undertaken by a total of fifty (50) parents was analyzed. All the parents unanimously reported that COVID-19 pandemic has adversely affected access to the professional health care services for regular mapping and troubleshooting of the speech processor and thus their children’s rehabilitation. However, active involvement between the professional health care services and the parents through video consultation and tele auditory verbal therapy has definitely helped the children to a great extent.Conclusion: The present study emphasises the great challenge posed by the COVID-19 pandemic for continued rehabilitation of CI children. To overcome this situation, an innovative digital media to address such medical issues through tele medicine, tele audiology and tele therapy is warranted.
EFEITO DO BIOATIVADOR DE SOLO NO DESENVOLVIMENTO INICIAL DO CAFEEIRO
Authors: Souza Eduardo Martins de , Junior Kleso Silva Franco , Brigante Giselle Prado , Brockelmann Carlos Eduardo , Tavares Renata Mendes , Dias Márcio de Souza , Marques Douglas José , Carneiro João Paulo Costa
Published: September 2020

A cafeicultura tem grande importância econômica no território nacional, entretanto, enfrenta algumas limitações no seu manejo, principalmente na sua implantação, pelo fato de comprometer todo o processo produtivo. A utilização de bioativadores de microrganismos no solo na instalação de lavouras cafeeiras gera um impacto de reciclagem de nutrientes auxiliando no aproveitamento, desenvolvimento e absorção da lavoura cafeeira. Os bioestimulantes à base de algas marinhas, enzimas e microrganismo solo, vêm sendo utilizados como uma alternativa para nutrição de plantas, pelo fato da intensa demanda de nutrientes no sistema atual de agricultura. Neste estudo, objetivou-se verificar o efeito de diferentes dosagens de bioativador de solo (Vitasoil®) na implantação de lavoura cafeeira (Catuai 144 vermelho). Foram testados uma aplicação via solo em 5 doses de 4, 6, 8,10 e 12 gramas por planta, somada a 3 aplicações de 3 gramas via foliar na mesma, para fazer a utilização da mesma ocorreu a hidratação com 100 ml de água para cada grama de produto. Aos 120 dias foram realizadas avaliações no experimento, medições da parte aérea e radicular, contagem de folhas, espessura do caule, pesagem da fração aérea e radicular verde e seca, área foliar e relação parte aérea /raiz. O delineamento experimental foi em blocos ao acaso. Entre os dados analisados observou que o uso do bioativador se mostrou superior estatisticamente quando comparado à testemunha, não diferindo entre si em dosagens. O ativador de microbiota de solo (Vitasoil®) aplicado via solo e foliar em mudas de café, promoveu um melhor desenvolvimento inicial do cafeeiro sendo observado em diâmetro, peso verde e seco, número de folhas por muda, área foliar, altura de planta, comprimento de raiz e relação parte aérea/raiz.
Open Educational Resources in Canada 2020
Authors: McGreal Rory
Published: September 2020

COVID 19 has had a wide impact on education internationally and specifically in Canada, with nearly all institutions now transitioning to online education, with many learning for the first time about Open Educational Resources (OER). Understanding what is happening with OER in the different regions of our country is one step in creating awareness and promoting national networks for sharing resources, serving to address local educational needs. Educators can assemble, adopt, adapt, design, and develop OER-based courses that can cost-effectively address the needs of Canadian students. This paper describes OER-related initiatives and implementations across Canada that can serve as examples to educators and administrators, who because of COVID 19, are offering online courses for the first time.
Acetogenin Extracted from Annona muricata Prevented the Actions of EGF in PA-1 Ovarian Cancer Cells
Authors: Periyasamy Loganayaki , Muruganantham Bharathi , Deivasigamani Malarvizhi , Lakshmanan Hariprasath , Muthusami Sridhar
Published: September 2020

Background:

In individuals with ovarian cancer, an increase in the circulating level of the epidermal growth factor (EGF) is readily apparent. Ovarian cancer cells exhibit signaling pathway of the epidermal growth factor (EGFR) and respond to the EGF. Annona muricata (AM) has been shown to decrease ovarian cell proliferation however, role of AM in regulating EGF actions is not yet to be reported.

Objective:

In this study, we proposed that the fractionated compound acetogenin can inhibit the activation of EGFR-regulated signaling cascades such as MAPK7 / PI3K-Akt / mTOR / STAT upon EGF stimulation.

Methods:

Ethanolic extract was prepared for the whole AM plant and Thin Layer Chromatography (TLC) was performed to characterize the secondary metabolites and each fraction was assessed using kedde reagent for the presence of acetogenin. The effects of acetogenins were then tested on the survival of PA-1 ovarian cancer cells under basal and EGF stimulated conditions. To delineate the role of acetogenin in EGFR signaling cascades, the in silico docking studies were conducted.

Results:

The fraction of acetogenin decreased the viability of EGF induced PA-1 ovarian cancer cells that indicating the EGF inhibitory effects of acetogenin. The docking studies specifically illustrated that when the acetogenin binding with tyrosine kinase (TK) and regulatory unit (RU) which subsequently resulted in a reduction in EGF induced the survival of PA-1 ovarian cancer cells.

Discussion:

The vital regulatory role of acetogenin reported in this study indicate significant anticancer activities of acetogenin from AM. The in silico study of the acetogenin function predicted that it binds specifically to Asp837 (phosphor-acceptor site) of EGFR, essential for phosphorylation of substrates in the TK domain and RU which promote downstream signaling.

Conclusion:

Acetogenin isolated from AM effectively inhibited the survival of PA-1 ovarian cancer cells through impaired EGF signaling.
Expression of Rab3b in Human Glioma: Influence on Cell Proliferation and Apoptosis
Authors: Luo Qili , Liu Yueping , Yuan Zilin , Huang Lvshuai , Diao Bo
Published: September 2020

Background :

Glioma is the most common human central nervous system tumour with a high degree
of malignancy. Some Rab GTPases have significant effects on glioma.

Objective:

This study aimed to investigate the effect of Rab3b (Rab GTPase3b) on human glioma cell proliferation
and apoptosis by silencing Rab3b and to initially verify the value of Rab3b expression for the diagnosis
and progression in human glioma.

Methods:

Rab3b was silenced by siRNA transfection. Human glioma tissues and normal brain tissues adjacent
to glioma were obtained by surgery. Rab3b, P53, Caspase 7, Bax, and Bim mRNA and protein expression levels
were detected by quantitative real-time polymerase chain reaction (qRT-PCR) and Western blotting. Cell
proliferation was detected by the cell counting kit-8 assay, and the cell cycle and apoptosis were analysed using
flow cytometry.

Results:

Rab3b mRNA and protein expression in human glioma U251 and U87 cells were significantly downregulated
after Rab3b silencing. Rab3b silencing inhibited glioma cell proliferation by promoting cell cycle arrest
and induced apoptosis by upregulating the expression of apoptosis-related proteins. Rab3b expression in human
glioma (n = 33) was significantly higher than that in normal brain tissues adjacent to glioma (n = 15). In addition,
Rab3b expression levels in high-grade gliomas (WHO III-IV, n = 19) were also significantly higher than
those in low-grade gliomas (WHO I-II, n = 14).

Conclusion:

Rab3b expression levels are significantly related to the progression of gliomas. Moreover, Rab3b
silencing not only significantly inhibits cell proliferation in gliomas via cell cycle arrest but also promotes cell
apoptosis by upregulating the expression levels of apoptosis-related proteins; however these preliminary in
vitro results warrant validation on in vivo studies.
Oncogenic LncRNA CASC9 in Cancer Progression
Authors: Qi Yuying , Song Chaoying , Zhang Jiali , Guo Chong , Yuan Chengfu
Published: September 2020

Background:

Long non-coding RNAs (LncRNAs), with the length of over 200 nucleotides, that originate
from intergenic, antisense, or promoter-proximal regions, are a large family of RNAs that lack coding capacity.
Emerging evidences illustrated that LncRNAs played significant roles in a variety of cellular functions
and biological processes in profuse human diseases, especially in cancers. Cancer susceptibility candidate 9
(CASC9), as a member of the LncRNAs group, firstly found its oncogenic function in esophageal cancer. In the
following recent studies, a growing amount of human malignancies are verified to be correlated with CASC9,
most of which are derived from the squamous epithelium tissue. This present review attempts to highlight the
latest insights into the expression, functional roles, and molecular mechanisms of CASC9 in different human
malignancies.

Methods:

In this review, the latest findings related to the pathophysiological processes of CASC9 in human cancers
were summarized and analyzed, and the associated studies collected in systematic retrieval of PubMed
used lncRNA and CASA9 as keywords.

Results:

CASC9 expression is identified to be aberrantly elevated in a variety of malignancies. The over-expression
of CASC9 has been suggested to accelerate cell proliferation, migration, cell growth and drug resistance of
cancer cells, while depressing cell apoptosis, revealing its role as an oncogene. Moreover, the current review demonstrated
CASC9 as closely related to the neoplastic transformation of squamous epithelial cells and squamous
metaplasia in non-squamous epithelial tissues. Finally, we discuss the limitations and tremendous diagnostic/
therapeutic potential of CASC9 in various human cancers.

Conclusion:

Long non-coding RNA CASC9 likely serve as useful disease biomarkers or therapeutic targets
which be effectively applied in the treatment of different kinds of cancers.
Expression and Prognostic Significance of the MMP Family Molecules in Bladder Cancer
Authors: Shen Chong , Da La , Wu Zhouliang , Wang Yujie , Gao Shen , Tian Dawei , Hu Hailong
Published: September 2020

Background:

Bladder cancer (BC) is the 10th most common cancer worldwide with significantly varied prognosis in different pathological subtypes. MMPs, a group of enzymes, could involve in the invasion and metastasis of numerous
malignancies. The function of MMPs in BC is partly reported in several studies but with a great conflicts; hence, a systematic analysis of expression levels and prognostic values of these MMP genes are still to be determined.

Methods:

Firstly, differentially expressed genes (DEGs) of MMPs were identified in ONCOMINE, GEPIA and UALCAN
databases; and these DEGs were also detected by real-time RT-qPCR. More importantly, we investigated the clinical significance of these DEGs in BC patients via Kaplan-Meier (KM) Plotter, UALCAN and cBioPortal databases.

Results:

The study found that mRNA expression of MMP1/11 in BC samples was significantly higher than that in normal
bladder tissues, and MMP2/3 were lower in the former than in the latter. The expression level of MMP1/2/7/9/11/13/23B
were significantly related to the tumour stages. Furthermore, the prognostic analysis suggested that the high transcription
levels of MMP7 and low transcription levels of MMP23A were correlated with favorable relapse-free survival and overall
survival in the patients with BC, respectively. Notably, high MMP11/13 expression levels indicated poor overall survival
(OS) and relapse-free survival (RFS) in patients with BC.

Conclusion:

This study revealed that MMP1/2/3/7/9/11/13/23A/23B are possible prognostic biomarkers and clinical therapeutic targets for patients with BC.
miRNA-146a Improves Immunomodulatory Effects of MSC-derived Exosomes in Rheumatoid Arthritis
Authors: Tavasolian Fataneh , Hosseini Ahmad Zavaran , Soudi Sara , Naderi Mahmood
Published: September 2020

Background:

Rheumatoid arthritis (RA) is a severe inflammatory joint disorder, and several
studies have taken note of the probability that microRNAs (miRNAs) play an important role in
RA pathogenesis. MiR-146 and miR-155 arose as primary immune response regulators. Mesenchymal
stem cells (MSCs) immunomodulatory function is primarily regulated by paracrine factors,
such as exosomes. Exosomes, which serve as carriers of genetic information in cell-to-cell communication,
transmit miRNAs between cells and have been studied as vehicles for the delivery of therapeutic
molecules.

Aims:

The current research aimed to investigate the therapeutic effect of miR-146a/miR-155 transduced
mesenchymal stem cells (MSC)-derived exosomes on the immune response.

Methods:

Here, exosomes were extracted from normal MSCs with over-expressed
miR-146a/miR-155; Splenocytes were isolated from collagen-induced arthritis (CIA) and control
mice. Expression levels miR-146a and miR-155 were then monitored. Flow cytometry was performed
to assess the impact of the exosomes on regulatory T-cell (Treg) levels. Expression of some
key autoimmune response genes and their protein products, including retinoic acid-related orphan
receptor (ROR)-γt, tumor necrosis factor (TNF)-α, interleukin (IL)-17, -6, -10, and transforming
growth factor (TGF)-β in the Splenocytes was determined using both quantitative real-time PCR
and ELISA. The results showed that miR-146a was mainly down-regulated in CIA mice. Treatment
with MSC-derived exosomes and miR-146a/miR-155-transduced MSC-derived exosomes significantly
altered the CIA mice Treg cell levels compared to in control mice.

Results:

Ultimately, such modulation may promote the recovery of appropriate T-cell responses in
inflammatory situations such as RA.

Conclusion:

miR-146a-transduced MSC-derived exosomes also increased forkhead box P3 (Fox-
P3), TGFβ and IL-10 gene expression in the CIA mice; miR-155 further increased the gene expressions
of RORγt, IL-17, and IL-6 in these mice. Based on the findings here, Exosomes appears to
promote the direct intracellular transfer of miRNAs between cells and to represent a possible therapeutic
strategy for RA. The manipulation of MSC-derived exosomes with anti-inflammatory miRNA
may increase Treg cell populations and anti-inflammatory cytokines.
Transmissibility and Epidemicity of COVID-19 in India: A Case Study
Authors: Jinila Bevish , Shyry Prayla S.
Published: September 2020

Background:

The global outbreak of COVID-19 was first reported in
Wuhan, China, in the late 2019. The origin of the infection is still unclear. Over
time, it spread to 150 countries in the world, due to which, the World Health Organization
(WHO) declared the infectious disease to be pandemic.

Objective:

COVID-19 transmitted to India due to the arrival of travelers from
other countries. The transmissibility and epidemicity of COVID-19 in India are
exponential. So, in order to understand the above characteristics, specifically
COVID-19 status in India has to be analyzed. To gain better insight on the
matter, the state of Kerala is selected. The epidemiological characteristics of patients
in Kerala, South India, and the possible transmission of COVID-19 from
asymptomatic members to other peers are shown describing certain cases.

Methodology:

The COVID-19 dataset is taken from the Kaggle dataset. This dataset
contains the details of the infected patients from different states of India.
Statistical analysis techniques were used to analyze the distribution of the affected
cases in a particular state.

Case Presentation:

The analysis shows that there is a possibility of the transmission
of infection even during the incubation period. The recent trend in the number
of infected cases in India is discussed.

Conclusion:

The transmissibility of COVID-19 and its epidemicity in India are
discussed. Specifically, a case study on COVID-19 cases in the state of Kerala relating
transmissibility is also summarized. Further, data related to patents on coronavirus
is also discussed. From the analysis, it can be concluded that there is a
possibility of COVID-19 transmission even during the incubation period. The
preventive measures to overcome COVID-19 and methods to increase immunity
are discussed.
Integration of Fuzzy Logic and ABC Algorithm for Optimized Network Selection in Heterogeneous Wireless Environment
Authors: Litake Shilpa R. , Mukherji Prachi
Published: September 2020

Background & Objective:

Various Radio Access Technologies are integrated in the next
generation of Heterogeneous Wireless Networks. The coexistence of various kinds of wireless access
networks ensures high service quality (QoS) for the users. Seamless vertical handover plays a significant
role in providing ubiquitous access to users. The ability to select the optimal access network out of available
access networks decides the comprehensive performance of the system. A novel scheme: Handoff Urgency
Estimator and Target Access Network Selector using Artificial Bee Colony algorithm (HUETANSABC)
for deciding the necessity of handover and selection of the best network is proposed in this paper.
The objective of the proposed work is to choose the most promising access network out of available coexisting
networks for enhancing user experience. Fuzzy logic provides reliable results even when the input
parameters are random in nature and can not be defined precisely. Artificial Bee Colony is an effective
method for searching and optimization. Proposed system combines best of fuzzy logic and ABC algorithm
for timely initiation of vertical handover. To gather the required information for handover, services provided
by IEEE 802.21 standard are utilized. Proposed integration of fuzzy logic and the ABC algorithm has
resulted in a decreasing number of unnecessary handovers.

Methods:

The effect of varying context parameters is analyzed using Fuzzy Inference System to estimate
the urgency of handover. The optimization of a target access network selection process is
achieved using meta-heuristic method.

Results:

Simulation results on MATLAB indicate that the proposed system performs better than
ABC and Multiple Attribute Decision Making (MADM) techniques.
COVID-19: An Insight on the Third Respiratory Global Emergency of the Century
Authors: Batra Sonali , Sharma Sumit , Verma Payal , Arora Nikhil
Published: September 2020

Introduction:

COVID-19 presents a global emergency in recent days and as a consequence,
the whole world is in a state of war. Continuous efforts by researchers are being made to establish a
sound scientific understanding regarding the behavior of the virus and its pathogenesis.

Background:

In recent days, a lot of scientific data are published describing viral transfusion into host
cells, compared with SARS-CoV-1, viability of SARS-CoV-2, fatality and diagnosis of infection among
infected patients, thereby, motivating to make right decisions in order to treat and mitigate COVID-19.

Review Results:

Coronaviruses usually affect the respiratory tract and produce symptoms similar to
pneumonia with varied complications. The spike protein on the surface of the virus makes the SARSCoV-
2 phylogenetically different from other viruses of the corona family. SARS-CoV-2 has an affinity
to angiotensin converting enzyme-2 receptors present on human cells. The fatality of the disease is
found to be low, but the severity of the disease might vary from person to person. The incubation period
is 14 days but the symptoms like dry cough and high fever are evident around 3-7 days. Already known
anti-inflammatory immunomodulators and antiviral drugs are being tested and still under clinical trials.

Conclusion:

There are many current strategies which are being tried and practiced to overcome
this pandemic disease apart from precautionary measures. Although now, some decline has been
seen, but the question still remains the same of whether the scientists are approaching towards the clinical
solution, or are still in the midstream. This requires more study and intensive research to finally
come to a concrete conclusion.
The Internet of Things: Impact and Implications for Health Care Delivery
Authors: Kelly Jaimon T , Campbell Katrina L , Gong Enying , Scuffham Paul
Published: September 2020

The Internet of Things (IoT) is a system of wireless, interrelated, and connected digital devices that can collect, send, and store data over a network without requiring human-to-human or human-to-computer interaction. The IoT promises many benefits to streamlining and enhancing health care delivery to proactively predict health issues and diagnose, treat, and monitor patients both in and out of the hospital. Worldwide, government leaders and decision makers are implementing policies to deliver health care services using technology and more so in response to the novel COVID-19 pandemic. It is now becoming increasingly important to understand how established and emerging IoT technologies can support health systems to deliver safe and effective care. The aim of this viewpoint paper is to provide an overview of the current IoT technology in health care, outline how IoT devices are improving health service delivery, and outline how IoT technology can affect and disrupt global health care in the next decade. The potential of IoT-based health care is expanded upon to theorize how IoT can improve the accessibility of preventative public health services and transition our current secondary and tertiary health care to be a more proactive, continuous, and coordinated system. Finally, this paper will deal with the potential issues that IoT-based health care generates, barriers to market adoption from health care professionals and patients alike, confidence and acceptability, privacy and security, interoperability, standardization and remuneration, data storage, and control and ownership. Corresponding enablers of IoT in current health care will rely on policy support, cybersecurity-focused guidelines, careful strategic planning, and transparent policies within health care organizations. IoT-based health care has great potential to improve the efficiency of the health system and improve population health.
Expressions of Individualization on the Internet and Social Media: Multigenerational Focus Group Study
Authors: Mayer Gwendolyn , Alvarez Simone , Gronewold Nadine , Schultz Jobst-Hendrik
Published: September 2020

Background

Growing individualization within the past decades has been described as a fundamental shift in society. Studies have reported how the digital age promotes new forms of individualism with self-tracking technologies and self-presentation in social networks. Potential harmful effects on the mental health of young adults have already been at the forefront of research. However, 2 questions that remain unanswered are how emotional experiences and expressions of self-relatedness differ among generations in their usage of the internet and social media, and if an increasing individualism can be observed by this.

Objective

The aim of this study is to examine whether the use of the internet and social media has led people to be more concerned about themselves than former generations. The potential consequences of mental and emotional distress among different age groups are analyzed.

Methods

A focus-group approach was chosen to study the following age groups: Baby Boomers (those born in 1950-1965), Generation X (those born in 1966-1980), and Digital Natives (those born in 1981-2000). We organized 6 focus groups with 36 participants who discussed their private usage of the internet and social media, different devices, platforms and functions, communication behavior, and self-tracking. We applied inductive category formation and followed the Standards for Reporting Qualitative Research (SRQR) checklist.

Results

We found differences in the 3 studied generations regarding the reasons for their use of the internet and social media, the effects of this use, personal feelings and experiences, expressions of self-relatedness, and social relationships. The Baby Boomers voiced a wish to stay autonomous while being in contact with their personal network. Generation X included enthusiastic members who appreciate self-tracking for curiosity and fascination, as well as people who felt fears about data surveillance. The Digital Natives reported a wish to optimize their own body by self-tracking while being faced with norms and expectations that were communicated via the internet and social media.

Conclusions

All generations expressed self-relatedness, yet by different means. The Baby Boomers expressed less individualism than Generation X and the Digital Natives, who felt the highest strain due to social comparisons. However, all generations reported specific, potentially problematic consequences for their mental health. Age-specific coping strategies are necessary to promote a mentally healthy way of using the internet and social media.
Mental health of the COVID-19 patients in Bangladesh: an overlooked issue (Preprint)
Authors: Hasan Dr Mohammad Jahid , Tabassum Tamanna
Published: September 2020

UNSTRUCTURED

Abstract:
Mental health aspect of COVID-19 patients in Bangladesh are remained less focused and not addressed. Estimation of the disease burden were also absent till date. The telephone based survey comprising 237 patients revealed that overall prevalence of anxiety and depression are 55.7% and 87.3%, respectively. And being female are the independent predictor of both anxiety and depression. Considering the high comorbid burden, the mental health issue of these patients needs to be addressed and reinforce to the existing health system in a priority basis.
Impact of Roundtable on Sustainable Palm Oil (RSPO) Certification on The Indonesian CPO Exports to The Destination Countries
Authors: Rosyadi Fachry Husein , Darwanto Dwidjono Hadi , Mulyo Jangkung Handoyo
Published: September 2020

Palm oil is one of the commodities of plantation products that has an important role in economic activities in Indonesia because of its ability to produce vegetable oil which is much needed by the industrial sector. The potential development of Indonesia's palm oil exports is very high considering the many benefits derived from these products. Therefore, there is a need to ensure that CPO products have a sustainable nature, one of which is that CPO products must be RSPO certified. This study analyzes how the influence of various factors that can affect Indonesia's CPO exports, one of which is RSPO certification using panel regression with the basic gravity model. The data which is used in this research is panel data in the form of time series for 20 years with cross sections from five major importing during 1999-2018. The analysis shows that importer’s GDP and exchange rate significantly and positively affect Indonesia's CPO exports, while the population of the importing country has a significant and negative effect. The RSPO dummy variable shows a significant and positive value, meaning that there was a significant difference between CPO exports when the RSPO certification took effect before and after 2008. Although the RSPO has an effect on Indonesia's CPO exports, there are still a number of indicators from the RSPO that Indonesia has not been able to fulfill. That indicator can be used as a material for consideration to be adopted in national certifications such as ISPO so that Indonesian CPO products can be said to be sustainable so that they can reach wider export markets.
EKONOMI INDUSTRIKELAPA SAWIT DI INDONESIA SERTA KAITANNYA DENGAN PROGRAM PENELITIAN DAN PENGEMBANGAN
Authors: Wahyono Teguh
Published: September 2020

This paper presents the role of oil palm into national economy, especially into Gross Domestic Product, fiscal earnings, employment, and regional development. Thispaper also brings up research and development program of oil palm, in terms of technology and socio-economic, by considering governmental policy, especially Board of Agriculture Research and Development. "2003 oil palm production is Rp39.39 trillion, with the contribution to plantation, agriculture, and entire sector GDP are 84%, 13%, and 2%, respectively. Land tax (PBB) is Rp3.8 billion, income tax (PPh) Rp5.12 trillion, value added tax (PPn) Rp3.94 trillion, and export tax(PE) Rp731.85 billion. In the end of2003, area of oil palm is 5,247,171 hawith labor necessity is 35 people per 100 ha. There are 320 unit of oil mills,with total processing capacity is 13.521 ton fresh fruit bunches per hour.Each oil mill under 30 ton of FFB per hour processing capacity needs 136labor. More labor can be employed by downstream industry which provideraw material for oil palm. Plantation development also cover the development of physical infrastructure, i.e. road, bridge, school building, mosque, church, etc. Furthermore, it is followed by socio-economic development, i.e. commerce center, financial, education, health, sport, entertainment, etc. Technological innovation have been developed by Indonesian Oil Palm Research Institute through research and development program. Some technological package also have been produced, both upstream and downstream industries.
Participación social en la gobernanza del Área de Protección de Flora y Fauna Islas Golfo de California
Authors: Rodríguez-Franco Isidro Luis , Rodríguez Quiroz Gerardo , Muñoz Sevilla Patricia , García Urquídez Daniel , Vásquez León Marcela
Published: September 2020

Con el objetivo de generar propuestas que robustezcan la gobernanza ambiental, en el presente artículo se estudia la participación social en la gestión del Área de Protección de Flora y Fauna Islas Golfo de California. A partir de observación directa y de entrevistas semiestructuradas a 29 actores, se analizó la percepción de funcionarios, especialistas y usuarios respecto a dicha participación en el marco de una indagación con enfoque cualitativo. La mayor limitante para el análisis fue el rechazo abierto de algunos usuarios de esta área protegida a ser entrevistados por desconfianza a las entidades públicas. Da originalidad al artículo la recopilación de experiencias y percepciones de actores directos en la gestión del área mencionada. Se concluye que la Comisión Nacional de Áreas Naturales Protegidas carece de credibilidad ante la organización social como resultado de una instrumentación vertical de sus estrategias sin considerar de manera efectiva la participación de las comunidades afectadas.
PEMBERDAYAAN KAMPOENG RABBIT’S UNTUK MEWUJUDKAN DAERAH TENAYAN RAYA MENJADI OBJEK WISATA
Authors: Nanda Sri , Darwin Ranti
Published: September 2020

Kampoeng Rabbit’s is one of the new tourist attractions established in the city of Pekanbaru about 2 years ago precisely on February 2, 2017 which has a land area of 1190M2 and is located on Jalan Kenanga, Tenayan Raya, this place is a tourist magnet in the Pekanbaru area, especially the Tenayan Raya area. The objectives of this program are: 1) Designing Kampoeng Rabbit’s management to be a family-friendly tourist destination. 2) Building a plan in developing Kampoeng Rabbit’s in order to become a tourism place that has prospects going forward. Implementation methods of this activity include initial survey activities, problem identification, needs analysis, determination of target audiences, program formulation, formulation and measurement of program success indicators, program implementation, target audience development strategies, partnership and partnership, monitoring and evaluation, results workshop with stakeholders, reporting, and updating post-program target data per 4 months. The results of the activities for the time being are: 1) The people of the Region of Tenayan Raya, especially on Jalan Kenanga, Kelurahan Mentangor Kec. Tenayan Raya can directly feel the impact of this Kampoeng Rabbit’s tour. 2) This tourist spot is an educational tourist spot that provides a family-friendly atmosphere that is suitable for extended family trips. 3) Increase the income of Kampoeng Rabbit’s manager. 4) Making Kampoeng Rabbit’s attraction can be known and known by many people, especially outside the Pekanbaru area. 5) With the cooperation of the owner of the tourist attraction and local community leaders such as the Head of RT and RW Chairman can develop Kampoeng Rabbit’s empowerment program to make the Tenayan Raya area a family-friendly tourist attraction.
PENINGKATAN KEMAMPUAN BERBICARA BAHASA INGGRIS MELALUI TEKNIK MEMBACA BERITA DI SMA DEK PADANG
Authors: Kemal Edwar , Rahmat Wahyudi , Tiawati Refa Lina , Dwinitia Suci
Published: September 2020

Learning English, especially speaking skills, requires a variety of accurate strategies. The aim is to make it easier for students to learn English, the more ways they can learn it the easier it is to master it. However, it is important to remember that learning English is not learning knowledge that requires high logical reasoning, memorizing formulas, mastering tenses, grammar, and formal English grammar, and so on. But learning English is nothing more than a skill that is continuously practiced until it is accustomed, any language learned requires the practice of speaking the language learned.
MEMOTIVASI SISWA SMA DAN SMK NEGERI 1 AMPEK NAGARI MELANJUTKAN PENDIDIKAN KE PERGURUAN TINGGI
Authors: Ramayani Citra Citra
Published: September 2020

Minat siswa yang ada di SMA dan SMK Ampek Nagari Kabupaten Agam untuk melanjutkan pendidikan ke perguruan tinggi masih rendah yang dibuktikan oleh kecil persentase jumlah siswa yang melanjutkan pendidikan ke perguruan tinggi dibandingkan dengan jumlah tamatan setiap tahunnya sehingga setelah tamat sekolah kebanyakan menjadi pengangguran. Pengabdian ini bertujuan memotivasi siswa untuk melanjutkan pendidikanya ke perguruan tinggi. Kegiatan ini akan dilaksanakan di SMA dan SMK Negeri 1 Kecamatan Ampek Nagari Kabupaten Agam. Adapun rencana kegiatan ini diawalai dengan tahap persiapan berupa pemantapan jadwal dan koordinasi dengan Dinas Pendidikan Kabupaten Agam, penetapan peserta. Tahap kegiatan terdiri dari penyampain materi oleh pembicara mengenai 1) Pentingnya melanjutkan pendidikan ke perguruan tinggi, 2) Jenis-jenis perguruan tinggi dengan keunggulannya masing-masing, 3) Jurusan atau program studi yang ada perguruan tinggi, 4) Profesi pekerjaan dan lapangan pekerjaan yang dapat dipilih setelah tamat perguruan tinggi, 5) Fasilitas-faslitas/beasiswa-beasiswa apa saja yang tersedia perguruan tinggi, 6) Trik agar sukses dalam mengikuti seleksi masuk perguruan tinggi. Hasil dari pengabdian ini bahwa siswa SMA dan SMK Ampek Nagari Kabupaten Agam memiliki motivasi yang tinggi untuk melanjutkan pendidikannya ke perguruan tinggi dengan persentase sebesar 82%.
THE TRAINING OF TIE-DYE HANDICRAFT IN “DURIAN SABATANG” STUDIO IN KAMANG MUDIK VILLAGE AGAM DISTRICT SUMATERA BARAT
Authors: Emridawati Emridawati , Munaf Yuniarti , Salsabila Ulfa
Published: September 2020

The training of tie-dye handicraft was the activity of community service toward the community of “Durian Sabatang” studio in Kamang Mudik village, Kamang Magek Sub-district, Agam District, Sumatera Barat. This training aims at empowering village people with their potentials so they can be trained with tie-dye skill. This training is also one of efforts to boost village people’s economy, whether the results of this training can be sold to the neighboring villages (tourism “Bantoroyo, Tirtasari”) or to the market. Methodologically, this community service was categorized as qualitative design so its data that were collected through observation were then described in the form of written/oral words. Hence it was very useful to know, comprehend, and study the data collected during the activities of this community service in order to obtain accurate results of this community service scientifically. These results were then described and arranged into scientific report according to the format of LPPMPP ISI Padangpanjang. This community service used the techniques of observation, interview, and documentation and the methods of lecture, demonstration, and practice.Result achieved in this community service was the high enthusiasm of the teenagers in “Durian Sabatang” studio highly trained during it. It can be seen from these teenagers’ work result namely creating table cloth, bag, shawl, blouse, shirt, handkerchief, and pillowslip by applying the technique of tie-dye into the white fabric of primissima, cotton, weaving, and calico. For the coloring, five kinds of Batik dye with the composition of blue (AS-D+BBB), pink (AS-BS+S.R), yellow (AS-G + M.B), orange (AS + M.GG), and red (AS + M.B). This training was fully conducted with good patience, seriousness, precision, and cooperation so the participants were successful in making the products. This good result has made the participants want to buy additional Batik materials and colors for retraining.
UPAYA PERBAIKAN TEKNIK BUDIDAYA JAMUR MASYARAKAT NAGARI PANYALAIAN KECAMATAN X KOTO KABUPATEN TANAH DATAR SUMATERA BARAT
Authors: Indriati Gustina , Hidayat Yosmed , Chandra Yasrial
Published: September 2020

Belum maksimalnya penerapan teknik budidaya jamur oleh masyarakat telah memberikan pengaruh terhadap hasil produksi. Belum maksimalnya teknik yang dimiliki menyebabkan semakin lama waktu pengerjaan dan tingginya kerusakan pada baglok jamur tiram, seperti yang dialami pengusaha MycoAgro. Kegiatan ini bertujuan memperbaiki teknik budidaya jamur dalam rangka meningkatkan produksi usaha jamur yang dimiliki masyarakat. Kegiatan ini dilaksanakan di Nagari Panyalaian Kecamatan X Koto Kabupaten Tanah Datar Sumatera Barat. Metode yang digunakan berupa pendampingan masyarakat melalui penyuluhan dan pelatihan mitra dalam pembenahan sarana budidaya, pemantapan teknik budidaya yang sudah dan belum dikuasai mitra. Pembuatan standar operasional alat budidaya dan prosedur keselamatan kerja serta pemberian konseling motivasi wirausaha pada mitra.Hasil kegiatan menunjukkan telah terjadi peningkatan pemahaman teknik budidaya yang dikuasai mitra. Selama proses budidaya telah terjadi penurunan jumlah baglok yang mengalami kerusakan bila dibandingkan dengan sebelum dilakukannya perbaikan tek nik budidaya. Mitra telah mampu menyelesaikan baglok jamur dengan waktu yang lebih cepat dari sebelumnya. Selama proses budidaya baglok yang mengalami kerusakan hanya 10%, jauh lebih kecil bila dibandingkan dengan sebelumnya. Mitra juga telah mampu memproduksi bibit sendiri, mengetahui teknik budidaya jamur konsumsi selain jamur tiram dan mampu menggunakan media tumbuh selain sekam kayu. Berdasarkan kegiatan yang telah dilakukan dapat disimpulkan telah terjadi peningkatan usaha budidaya jamur tiram yang dimiliki masyarakat.