bluuebunny/crossref_metadata_2025 huggingface dataset:
RESEARCH ON THE ABILITY OF YARNS FOR TEXTILE PROCESSING
Authors: Slizkov Andrew , Mykhailova Halyna , Borolis Inna
Published: August 2022

The article is intended to study the destruction mechanism of yarns of different structures under different types of deformations that occur during their textile processing (weaving, knitting, etc.). Improving the wear resistance of yarns is one of the main ways to determine the causes of their destruction in textile processing with their subsequent elimination. The significance of this problem is determined by the fact that increasing the reliability and endurance of yarns is equivalent to increasing output without additional labor and material resources. The ability of yarns for textile processing is mainly determined by their mechanical characteristics in tension: tensile strength and elongation, endurance, longevity, cyclic elongation, and the like. In the regulatory documents, this ability is mainly assessed only by the indicators of tensile strength and elongation, which does not fully characterize their behavior in textile processing. Therefore, the study of the features of the yarn destruction under different types of mechanical interactions, as well as the impact of their structure on the process of destruction, is relevant for predicting their endurance and developing a new range of textile fabrics.
Investigating a Popular Belief: TV Series’ Roles in L2 Learners’ Speaking Fluency
Authors: Anis Etikasari  , Hardiyanti Tita , Susanti Ani
Published: August 2022

One of the most popular beliefs among English L2 learners is that watching English TV series can help them speak English language fluently. While it is seemingly genuine, as supported by many English learning websites and successful English L2 learners, further investigations on this subject matter have been minimal. Therefore, this research aims to find out the roles of TV series in improving English L2 learners’ fluency in English. In this qualitative research, in-depth interviews were conducted on two English L2 learners who claimed to have attained a certain level of fluency through intensive and independent watching of TV series. The results found that although TV series were not the primary strategy to obtain fluency in English, they had helped English L2 learners improve their fluency in speaking English in several ways. TV series also played a significant role as a plausible fluency enhancer for English L2 learners by providing learning motivation and exposure, acting as a role model of natural English, supporting linguistic features acquisition, and boosting the learner’s confidence to speak English. These aspects are not typically found while learning English in informal settings such as schools or English courses. These results add insights on how TV series could be a crucial supplementary material for L2 learning. Further research is recommended to determine the extent of TV series features in improving English L2 learners’ fluency in English.
A case of early-onset diabetes with impaired insulin secretion carrying a PAX6 gene Gln135* mutation
Authors: Sekiya Motohiro , Yuhara Mikiko , Murayama Yuki , Ohyama Osawa Mariko , Nakajima Rikako , Ohuchi Nami , Matsumoto Nako , Yamazaki Daichi , Mori Sayuri , Matsuda Takaaki , Sugano Yoko , Osaki Yoshinori , Iwasaki Hitoshi , Suzuki Hiroaki , Shimano Hitoshi
Published: August 2022

A paired homeodomain transcription factor, PAX6 (paired-box 6), is essential for the development and differentiation of pancreatic endocrine cells as well as ocular cells. Despite the impairment of insulin secretion observed in PAX6-deficient mice, evidence implicating causal association between PAX6 gene mutations and monogenic forms of human diabetes is limited. We herein describe a 33-year-old Japanese woman with congenital aniridia who was referred to our hospital because of her uncontrolled diabetes with elevated hemoglobin A1c (13.1%) and blood glucose (32.5 mmol/L) levels. Our biochemical analysis revealed that her insulin secretory capacity was modestly impaired as represented by decreased 24-h urinary C-peptide levels (38.0 μg/day), primarily explaining her diabetes. Intriguingly, there was a trend toward a reduction in her serum glucagon levels as well. Based on the well-recognized association of PAX6 gene mutations with congenital aniridia, we screened the whole PAX6 coding sequence, leading to an identification of a heterozygous Gln135* mutation. We tested our idea that this mutation may at least in part explain the impaired insulin secretion observed in this patient. In cultured pancreatic β-cells, exogenous expression of the PAX6 Gln135* mutant produced a truncated protein that lacked the transcriptional activity to induce insulin gene expression. Our observation together with preceding reports support the recent attempt to include PAX6 in the growing list of genes causally responsible for monogenic diabetes. In addition, since most cases of congenital aniridia carry PAX6 mutations, we may need to pay more attention to blood glucose levels in these patients.

Learning points

PAX6 Gln135* mutation may be causally associated not only with congenital aniridia but also with diabetes.

Blood glucose levels may deserve more attention in cases of congenital aniridia with PAX6 mutations.

Our case supports the recent attempt to include PAX6 in the list of MODY genes, and Gln135* may be pathogenic.
KESADARAN TEOLOGIS MASYARAKAT CIKADUT DALAM MENGHADAPI PANDEMI COVID-19
Authors: Khalil Gibran Sulthan Faiz
Published: August 2022

The Covid-19 pandemic has melted all aspects of life, whether social, economic, educational, political and so on, religion has become the highest theological awareness for humans to get closer to the creator. Therefore, the purpose of this research is to answer some of the main issues that are the subject of discussion, about how is the theological awareness of the Cikadut community in dealing with Covid-19? This research is a field research, with qualitative methods as a data collection technique and Islamic theology as a knife of analysis. The results of this study indicate that the Cikadut community has various views in responding to the Covid-19 disaster, some believe it and vice versa. There are various ways that the Cikadut community uses to get out of the problem. Among them is theological awareness, in which humans surrender themselves to return everything that exists in this life to God who is omnipotent. And then make every effort to avoid provisions that are deemed unsuitable for life.
PENGARUH TADARUS Al-QUR’AN TERHADAP SIKAP MENGHARGAI SESAMA MANUSIA: Penelitian Eksperimen pada Kasus Bullying Siswa SD kelas 2 SDIT Bhakti Pertiwi Baleendah Bandung
Authors: Yanti Irma
Published: August 2022

Mutual respect for fellow human beings needs to be applied since the child's early life, a design that can be applied is one of them with tadarus al-Quran. This study intends to gain knowledge about the effect of tadarus al-Qur'an on the attitude of respect for fellow human beings. Quantitative approach with one group pretest and one posttest experimental design used in this study. The data analysis process used the IBM SPSS Statistict 25 application. This study resulted in the opinion that the influential Qur'anic tadarus can increase the attitude of respect for fellow human beings in second grade students of SDIT Bhakti Pertiwi Baleendah Bandung with a probability of 0.000 < 0.05. That is, tadarus al-Qur'an can be an alternative way in developing mutual respect for fellow human beings in children. The entire sample in this study experienced an increase in respect for fellow human beings. As evidenced by descriptive statistical data, it is known that the difference in the average value of mutual respect, before and before learning treatment using the Qur'anic tadarus method for ten times of treatment. This study proves that mutual respect for fellow human beings can be improved through the Qur'anic tadarus learning method.
Halal Lifestyle dan Wara’ Lifestyle (Studi Kasus Pusat Halal Salman ITB)
Authors: Zaidah Nurul , Solihin Muhtar , Muliadi Muliadi
Published: August 2022

Halal lifestyle is a growing trend today, where the halal lifestyle is a lifestyle that applies everything that is halal or does not conflict with the teachings of Islam. wara', although halal lifestyle is a trend that continues to grow, there are still many who do not understand what a halal lifestyle is, therefore it is necessary for the role of various parties to give special attention so that Muslims get a complete understanding of the concept of halal lifestyle. as done by the Salman ITB Halal Center institution. The purpose of this research is to find out the halal lifestyle and wara' lifestyle, the history of the Salman ITB Halal Center, and the role of the Salman ITB Halal Center in implementing halal lifestyle as a practice of wara' values. The method used is qualitative with the type of case study research using interview, observation and documentation techniques. As for the results of this research, halal lifestyle and wara' lifestyle have harmony so that halal lifestyle is a practice of wara' values. The establishment of the Salman ITB Halal Center was motivated by the issuance of the Halal Product Guarantee Act in 2014, as well as the role of the Salman Halal Center in implementing halal lifestyle which is a practice of wara' values, which can be seen from the vision of the Salman ITB Halal Center which is to become a superior da'wah institution for system services. guarantee of halal products to the public with the strength of halal and professional human resources as well as derivatives of the program organized by the Salman ITB Halal Center.
Manusia dalam Pandangan Ali Syariati dan Abdurrahman Wahid: Studi Filsafat Manusia
Authors: Kalimi Rizki Mohammad
Published: August 2022

At this time, human problems and all things related to it, more and more diverse. Unfortunately, science and technology, which were originally expected to provide a solution to these problems, have instead become a source of new problems. On the other hand, humans who are equipped with reason to think and ask questions, constantly try to explore the meaning of the mystery of who he is. Many thinkers have contributed their thoughts on the concept of man, but of these, it gives the impression that the deeper the meaning of man is dug, the more the basis for this search will not be found. This study aims to examine further the meaning of humans, so that by revealing the meaning of humans, humans can answer complex problems in themselves. The research method used is a qualitative method, based on the primary books of the characters being studied, and secondary data that supports these primary sources. This research resulted in a finding that humans have an essence where it is this essential thing that ultimately makes a person truly human.
LANDASAN TEOLOGI DALAM TRADISI ASYURA MASYARAKAT SYIAH DI DESA PASIRHALANG
Authors: Dwi putra Defani Mauludi
Published: August 2022

The purpose of this study is to describe the main research topics: 1). Community understanding of ashura in Pasirhalang Village; 2). Theological analysis in the perspective of the Shia school of ashura in Pasirhalang Village. This research is a field research, with descriptive qualitative method, and Shia Imamiyya theology as a knife of analysis. The findings in this study are first, various kinds of cultural traditions in commemorating the asyuroan, namely: the shura porridge tradition, telling the history of Husein in Karbala (maktal), tawasul, pilgrimage, tahlil. Second, the theological basis for the Ashura tradition of the Shia community in Pasirhalang Village.
The optimization of louvers shading devices and room orientation under three different sky conditions
Authors:   Doctoral program, Graduate School of Environmental Engineering, The University of Kitakyushu, Japan, Khidmat Rendy Perdana ,   Architecture Study Program, Department of Infrastructure and Regional Technology, Institut Teknologi Sumatera, Indonesia, Fukuda Hiroatsu ,   Department of Architecture, Faculty of Environmental Engineering, The University of Kitakyushu, Japan, Paramita Beta ,   Architecture Study Program, Faculty of Technology and Vocational Education, Universitas Pendidikan Indonesia, Indonesia, Koerniawan M. Donny ,   School of Architecture, Planning, and Policy Development, Bandung Institute of Technology, Jalan Ganesha 10, Bandung 40132, Indonesia, Kustiani Kustiani ,   Department of Architecture, Faculty of Engineering, Bandar Lampung University, Lampung, Indonesia
Published: August 2022

This paper presents parametric and multi-objective optimization (MOO) approach in optimizing daylight and energy consumption by incorporating louvres shading devices depicting three different sky conditions: Birmingham, UK, Jakarta, Indonesia, and Sydney, Australia. The study aims to observe the best louvre design configuration for each given context. The proposed optimization system iterates the logic of the louvre shading device as the dynamic design parameters such as overhang, blade size, spacing, and blade rotation, together with the room orientation to achieve maximum useful daylight illuminance (UDI) and the shading aperture while simultaneously reduces energy consumption. A total of 8509 simulations for three cities have been run and distributed for the purpose of this research. The results of MOO stated an improvement in UDI for Birmingham, Jakarta, and Sydney of 80%, 146.26%, and 79.48%, and cooling energy consumption of 28%, 3.26%, and 2.99% respectively.
The Improvement of Science Learning Outcomes and Intrapersonal Intelligence Through Course Review Horay of Third Grade Students at MI Mazra’atul Ulum 01 Lamongan
Authors: Ikrima Ikrima
Published: August 2022

This research was conducted because the learning process is lack student’s enthusiasm and passion, it tends to be not interested learning. The previous student learning outcomes were only 13% who reach the minimum completeness criteria. Learning so far has used the lecture method so it is necessary to apply a course review horay strategy. This research was conducted at MI Mazra'atul Ulum 01 Lamongan. The method used in this research is classroom action research which consists of 2 cycles, each cycle through 4 stages, namely planning, implementation, observation, and reflection. Data were obtained through interviews, questionnaires, worksheets and documentation. Data on student learning outcomes were analyzed by SPSS to determine the increase in students learning outcomes and intrapersonal intelligence in each cycle. The results showed that: (1) The implementation of the course review horay strategy has done well because it is able to increase the activities of teachers and students. In the pre-cycle teacher, activity has a percentage of 58% (less), cycle 1 has a percentage of 71% (good), and cycle 2 has a percentage of 73% (good). In the pre-cycle student’s activity has a percentage of 42% (less), cycle 1 has a percentage of 58% (less), and cycle 2 has a percentage of 83% (good). (2) Data on student learning outcomes in the pre-cycle has a percentage of 13% with an average of 48.8 (less), in cycle 1 got a percentage of 94% with an average of 78.2 (good) and in cycle 2 got a percentage of 94% with an average 78.6 (good). (3) Intrapersonal intelligence in pre-cycle has a percentage of 40%, cycle 1 has a percentage of 88%, and cycle 2 has a percentage of 96%.
Diagnostics of Self-Efficacy Assessment Instruments in The Form of Problem Gain Test Based on Science Education Material
Authors: Amalina Wafa , Fadly Wirawan
Published: August 2022

This study investigated to produce an instrument product that discusses the problem of science. This study was adapted from the instrument. How to determine the questionnaire by looking at the compatibility of self-efficacy indicators. The effectiveness of the instrument assesses the test of consideration between the instrument and the self-efficacy questionnaire on each indicator and its suitability with the Natural Sciences material. The collected data was analyzed descriptively quantitative and qualitative. The results of the correlation in each indicator are positive and negative, but the whole shows a positive correlation. Based on the test results, the instrument was developed for use.
Students’ Perceptions of Hybrid Learning in The Face-To-Face Meeting System (PTM) Limited to Science Lesson at The MTs Level
Authors: Paramitha Silvia Melinda , Nurul H. Lisdityanti , Zahroh Dinafil A Farda , Tasyana W.F. Putri , Indayati Tatik , Lastutik Mudji , Utami Sri , Maromi Lailul
Published: August 2022

This study aims to determine students' perceptions of learning Hybrid Learning in the Limited PTM System in Science Subjects Class IX at the SMP/MTs level. The research method uses descriptive qualitative methods. The data in the study were in the form of a questionnaire with 14 questions to students. The data analysis technique in this qualitative research is using data reduction, data presentation, and conclusions. One of the advantages of implementing Hybrid learning is being able to improve students' cognitive learning outcomes. However, in limited PTM the problem faced by students is limited student social interaction, students have difficulty understanding the material. So, among the weaknesses in limited PTM it is assumed that Hybrid Learning is able to overcome problems that occur when PTM is limited. So, it is important to do this research. The results of this study namely students' perceptions of Hybrid Learning learning that Hybrid Learning makes it easier for students to understand the material, students feel happy when learning Hybrid Learning because they can communicate directly both with teachers and with friends. So, it can be concluded that students' perceptions of Hybrid Learning give a positive response.
Completeness of Science Literature Elements in Class VII Science Literacy Assessment Instruments
Authors: Falantin Liis Kurnia , Qosyim Ahmad
Published: August 2022

This study was conducted with the aim of identifying the presentation of scientific literacy aspects in the scientific literacy assessment instrument for the seventh grade science material. This study uses qualitative descriptive analysis. The object of research in this study is the scientific literacy assessment instrument from the researcher Muftianah and Wahono (2018), and the researcher Arfianti (2015). The data collection technique used is literature study. The data analysis technique in this research uses content analysis. The results of the study indicate that aspects of scientific literacy have been presented well, although there is one aspect that has not been included in the scientific literacy instrument, namely the scientific process aspect. In the scientific literacy instrument for the two researchers, the aspect of scientific literacy that often appears is the aspect of science content. Thus, in measuring scientific literacy skills, all aspects of scientific literacy must be contained in scientific literacy instruments. Based on the results of the study, it can be concluded that the aspect of scientific literacy, the two instruments that have been analyzed there is one aspect that has not been included in the scientific literacy instrument, namely the scientific process aspect. In the scientific literacy instrument of the two researchers, the aspect of scientific literacy that often appears is the aspect of science content. Thus, in measuring the ability of scientific literacy, all aspects of scientific literacy must be contained in scientific literacy instruments.
Network pharmacology approach to delineate relationship between type 2 diabetes mellitus and triple negative breast cancer
Authors: Akbar Aimen , Banerjee Subhamoy
Published: August 2022

Type 2 diabetes mellitus (T2DM) is a metabolic disorder which plays a key role in varieties of other diseases like including cancer. Triple negative breast cancer (TNBC) is an aggressive subtype of breast cancer with poor clinical outcome. Due to the absence of some of the key surface
receptors in TNBC, the arsenal of anticancer therapeutics is left with limited options. Comorbidity analysis can give us significant insights into disease cross-talk and it has potential to develop more efficient targeted therapeutics. The correlation between TNBC and T2DM is not very clear.
We have analyzed microarray dataset for T2DM and TNBC obtained from gene expression omnibus (GEO) and identified differentially expressed genes. Further, the list was enriched using Genecodis and protein-protein interaction network was constructed using STRING database. The molecular comorbidity
index and Jaccard coefficient was calculated between the DEGs. Also, T2DM –TNBC network was constructed and module analysis was done using Cytoscape. Enrichment analysis indicated extracellular matrix modification, growth factor receptor overexpression, adipokine mediated signaling in
breast adipocyte tissues may link the T2DM and TNBC.
Nanotechnology Solutions To Mitigate Covid-19 Challenges
Authors: Dutta Aishi , Datta Soumi
Published: August 2022

The COVID-19 pandemic has fuelled a global demand for effective diagnosis. Millions have lost lives in the face of this current health threat. The first case of COVID-19 was reportedly found in December 2019 in Wuhan, China. Since then, effective strategies for early detection and plausible
treatment of COVID-19 to reduce the viral load and contain its global transmission have been under rigorous research. Theragnostic nanoparticles have been a promising tool for efficiently delivering therapeutic moieties like drugs, vaccines, siRNA, peptides to target infection sites. In this
article, we shed light on the role of nanotechnology as effective carriers for immune modulators for fighting against Covid-19 and its relevance in biosensors and care tests. On account of their high bioavailability, sustained and controlled release profiles, and properties like imaging and
targeting, nanomaterials are extremely useful for antigen delivery. Nanomaterials have an impact on the immune responses to a vaccine. Their physicochemical properties, counting size, surface charge, and surface modification, affect their resulting immunological outcomes. We aim to examine
the preliminary concepts of virology and provide brief information to promote new insights into the evolution of novel vaccine adjuvants. We also discuss nanotechnology-based strategies like 3D printing, antiviral coatings, and therapeutics to combat this pandemic. The challenges and the drawbacks
involved have also been highlighted.
Simultaneous relocation strategy of bromeliads as epiphytes or terricolous in the Montane Dense Ombrophilous Forest of Parque Estadual da Cantareira, São Paulo State, Brazil
Authors: Nievola Catarina Carvalho , Kanashiro Shoey , Tamaki Vivian , Guardia Marina Crestana , Suzuki Rogério Mamoru , Costa Janaina Pinheiro , Baptista Waldyr , Cachenco Mônica Valéria , Shidomi Yoshito , Santos Junior Nelson Augusto dos
Published: August 2022

Plant relocation resulting from vegetation removal is an important conservation strategy. This work aimed to investigate the simultaneous relocation of the bromeliads Aechmea distichantha Lem. and Wittrockia cyathiformis (Vell.) Leme in epiphytic and terricolous form. These bromeliads were rescued from deforested areas due to the construction of a highway. Both were fixed onto tree trunks or pitchforks or in the soil in a Montane Dense Ombrophilous Forest area of Parque da Estadual Cantareira, São Paulo State, Brazil. After one year A. distichantha maintained 100% survival rate, when transplanted in terricolous and 83.33 % in epiphytic form, while W. cyathiformis was 60% for both relocation forms. We concluded that both bromeliad species could be simultaneously relocated as epiphytes or terricolous. Direct relocation to the ground guarantees practicality, as it is difficult to find trees with forks located at small heights from the ground in which the manual fixing of the plant could be done without equipment.
Jogos Didáticos no Ensino de Botânica: Enraizando e Batalha Algal
Authors: Oliveira Neto Fernando Fernandes de , Jorge Taciane Schröder , Garcia Cleisson Schossler , Dalzotto Débora Presmini , Costa Juliene Lopes , Medina Thais Gotuzzo de Menezes , Iganci João
Published: August 2022

A Botânica é negligenciada no ensino de Biologia para o ensino fundamental e médio. Dessa forma, o Projeto de Ensino Jogos Botânicos, do Laboratório de Sistemática e Evolução de Plantas da Universidade Federal de Pelotas, foi criado para abordar o ensino de Botânica de forma lúdica, buscando tornar os assuntos relacionados ao reino das plantas mais interessantes e próximos da comunidade. Nesse sentido, foram elaborados jogos didáticos com intuito de apresentar os assuntos de forma simples e atraente aos estudantes. O jogo Enraizando foi inspirado em um tabuleiro dinâmico de xadrez, tornando o ensino de fisiologia vegetal mais interessante aos alunos. Da mesma forma, o jogo Batalha Algal foi inspirado no jogo batalha naval, dinamizando os conteúdos referentes às algas. Este trabalho apresenta propostas didáticas no ensino de Botânica, a fim de auxiliar os professores, do ensino fundamental e médio, em uma transposição didática mais efetiva e de maneira lúdica.
Visualization and Crossword: In-class Exercise---An active learning Strategy
Authors:   Dept. of Humanities and Sciences, Walchand Institute of Technology, Solapur, Maharashtra, India., Joshi Preeti S.
Published: August 2022

Objective: Implementation of active learning methods into classroom enhances the learning experience of students. Instructional strategy followed by proper active learning activity increases engagement, attention, thinking skill of students. This study was carried out to incorporate an instructional strategy i.e visualization followed by active learning activity- crossword puzzle to first year B.Tech students and to find out its effectiveness in the learning process Methods: The animated videos available on internet were used for visualization. Then by using free online resources, crossword puzzles were created and provided to the students. Evaluation was done by crossword puzzle as well as by feedback in the form of questionnaire using a 5-point Likert scale. The data was collected and analyzed.Results: More than 90% students indicated that visualization and crossword puzzle enhanced their learning, oriented to the important topics and served as good tool in effective learning of engineering physics.Conclusions: This activity contributed to a helpful learning experience which allows the students to engage better in the learning, to review the lecture material as well as examination and also provides a more relaxed and friendly classroom atmosphere by proper break in the lecture without breaking learning. Keywords: Active learning, Visualization, Crossword puzzles, Questionnaire.
A Learning Model for Effective Teaching of Entrepreneurship Engineering Using Workshop Technology As A Case Study
Authors:   Mechanical Engineering Department, Osun State University, Osogbo, Nigeria., Idris Musibaudeen Olatunde , Adeyemi Oluseyi Afolabi , Adeboye Busayo Sunday , Oyelami Seun
Published: August 2022

Abstract: For over a decade that Entrepreneurship education was introduced to the curriculum of tertiary institutions in Nigeria, majority of engineering students only acquired the skill but lacked the entrepreneurial spirit to initiate their personal engineering based ventures. This attitude could be traced to the structure of the curriculum of entrepreneurship education which is generic in nature that could hardly bring out the t echni cal entrepreneurship values that were embedded in engineering education. To close this gap, there is the need to integrate entrepreneurship education into the engineering curriculum without sacrificing the technical and professional objectives of the course. This study developed a learning model based on the course outline of Workshop Technology and the behavioural object ives of Introduction to Entrepreneurship to develop an Entrepreneurial induced version of Workshop Technology which adopted modular-based pedagogy for effective learning. The model aimed to produce entrepreneurial minded engineering graduates that will willingly prefer to create engineering ventures after graduation.The model was given a prima facial evaluation by the experts in engineering and entrepreneurship and was adjudged to be appropriate for its purpose. Keywords: Entrepreneurship, Engineering, Education, mindset, pedagogies, curriculum
Detection of Lower Extremity Occlusive Peripheral Artery Disease (LEOPAD) by Measuring Systolic Pressure Index in Type 2 Diabetic Patients
Authors: IB Nacef , D Khelifi , I Rojbi , Y Lakhoua , N Mchirgui , K Khiari
Published: August 2022

Objective: The aims of our study are to identify the prevalence of LEOPAD in type 2 diabetes, to study the predictive factors of LEOPAD and to demonstrate the importance of establishing a specialized screening consultation in diabetic patients with LEOPAD and with high cardiovascular risk. Research design and methods: We carried out a prospective and descriptive study. The study involved 150 patients with type 2 diabetes who were followed on a regular basis. The different epidemiological, clinical and biological data were collected patient’s medical file. Each patient was investigated for cardiovascular risk factors. A thorough physical examination was performed in addition to biological assessment (fasting plasma glucose, HbA1c, lipid profile). After consent had been obtained, all patients underwent the ankle-brachial systolic pressure index (ABI) test. Results: The mean age of our patients was 57.46 ± 8.04 of the 150 patients, 24.7% had abnormal ABI suggestive of lower limb ischemia. Among them, 8.7% had an ABI of 1, 3, a presumed marker of vascular stiffness. The mean age of the LEOPAD population was 58 years. LEOPAD was predominantly asymptomatic in our population (88.1%). Only 5 patients (11.9%) had intermittent claudication. The comparative study of patients with LEOPAD showed a statistically conversely significant correlation between LEOPAD and lower levels of HDL. However, there is no statistically significant correlation with the following factors: smoking, sex, hypertension, dyslipidemia, obesity or overweight android pattern, the presence of microalbuminuria, renal failure and sedentary lifestyle. In terms of glycemic control, it did not show a statistically significant difference between the two groups. Moreover, it was noted that the patients with LEOPAD had had more micro vascular complications compared to patients without LEOPAD. Conclusion: Lower extremity occlusive peripheral artery disease occurred more commonly than it was expected in the diabetic population, associated with a high cardiovascular comorbidity. The sensitivity, specificity and simplicity of the ABI measurement promote its routine use and integration into the clinical approach of high-risk LEOPAD patients, especially the diabetics.
THE FUTURE OF HISTORY OF PHILOSOPHY (AN EDITORIAL)
Authors:   Ural Federal University named after the first President of Russia B.N. Yeltsin, Pertsev Aleksandr V. , Vnutskikh Alexander Yu. ,   Perm State University
Published: August 2022

This paper presents the key theses summarizing the main points of the articles written for the thematic issue «The Future of History of Philosophy». The authors of the articles are representatives of the Ural School of History of Philosophy — V.B. Kulikov, A.V. Pertsev, and E.S. Cherepanova, who were students of K.N. Lyubutin, and also the well-known expert on Plato’s works from St. Petersburg R.V. Svetlov. Each of these authors finds their own way to pose the question of the future of the history of philosophy in the con-text of unprecedented dynamism of sociocultural systems. For example, R.V. Svetlov explores the situation of ʽrediscoveringʼ of the history of philosophy within the framework of analytic philosophy, which has be-come a philosophical tradition. On the other hand, the history of philosophy itself could not remain un-changed under such impacts. Critical rethinking of established ideas is commonplace of contemporary re-search in the area of history of philosophy. R.V. Svetlov challenges the well-established view that Platonism is based on the idea of the dominance of reason in human nature. On the contrary, Plato’s conception ap-pears to be an account of the fundamental incompleteness and uncertainty of man’s position in being. A.V. Pertsev demonstrates the value of attempts to reconstruct the holistic world of famous philosophers on the basis of the whole set of documents recording the circumstances of their life using the example of Frie-drich Nietzsche. Such research is an effective means of restoring the integral human in our atomized con-temporaries. E.S. Cherepanova explores the philosophical aspects of the work of Austrian writer G. Broch. She shows the inhumanity and anti-intellectualism of the positivist alternative to bourgeois society. The ʽbusinesslikeʼ nature of its individuals saves them neither from economic upheaval nor from the horrors of another world war. V.B. Kulikov points to the potential of dialogical perception of Buber’s philosophical anthropology in periods of human ʽhomelessnessʼ, when a person realizes the homelessness of this world and becomes problematic, becomes a question for himself. The question each of us has to answer.
FRIEDRICH NIETZSCHE: THEOLOGY, METAPHYSICS AND PSYCHOLOGY IN SEARCH OF VITALITY
Authors:   Ural Federal University named after the first President of Russia B.N. Yeltsin, Pertsev Aleksandr V.
Published: August 2022

The author believes that the current socio-cultural situation caused by the pandemic opens up the potential for intensified research in the field of history of philosophy. However, it is important to orient this research toward reconstruction of the integral world of a particular thinker based on the entire set of documents that record the circumstances of his life. The paper demonstrates this approach as applied to the Friedrich Nie-tzsche: his reflections and the process of work in the fields of literature, philosophy, psychology, music, and medicine are demonstrated in the context of the circumstances of his personal life and relations with his relatives. In parallel, the hermeneutic components of the modern biographical approach are clarified. The content of the psychological concept of «introvert» is compared with its philosophical and theological meaning. The author considers the interpretation of an introvert as a subject closed in itself and not useful for the society to be wrong. Based on texts written by Nietzsche, the author substantiates that the psycholog-ical type of an introvert implies a «super-social altruist» who splits his/her Self and places these elements in-to all things and all creatures of his/her inner world. At the same time, the «split Self» remains whole, main-taining the connection of everything to everything in the «inner world» and is therefore responsible for it. Thus, the worldview of an introvert (for example, a playwright, theologian, philosopher) is somewhat of a «meaning-making play» which he/she presents to the world so that the world could live according to it.
«IT’S LIKE TWO WORLDS!»: REIFICATED AND HUMAN REALITIES
Authors:   Perm State University, Loskutov Yuri V.
Published: August 2022

The article deals with the philosophical problem of reification in the ontological, gnoseological and axio-logical aspects. The problem of reification was discovered by Patristics, but the theoretical development of this problem was carried out in Marxist philosophy. In the process of historical formation of a human, matter «polarizes», splits into human subject reality and reificated subject reality, which act as objectively existing fictions in relation to each other. Reification of social reality, which excludes a human as a free subject, does not correspond to human essence, and therefore it acts for a human as a non-genuine reality, generating non-genuine values. Reification (together with its «otherness» — fetishism) generates trans-formed social forms, through which the concept of fact is problematized. This allows us to propose the following hypothesis: if conditional statements describing causal relations in genuinely human reality are designated as factual, then conditional statements describing causal relations in reificated subjectivity must be designated as counterfactual, and conversely. The objective existence of two mutually exclusive subject worlds places science in the situation of choosing between alternative — human or anti-human — models of reality. At the same time, a human appears as a «macrocosm» in the non-reificated human worldview model, and his human reality is constituted in this empirically valid model by a special social substratum that makes all human individuals essentially identical to each other. When describing and ex-plaining social processes, it makes sense to specify which of the two mutually exclusive realities — the reificated or the human one — is being considered in each case.
IMPLICIT PREDICTIONS OF MARRIAGE SATISFACTION BASED ON PERCEPTION OF EXPRESSIVE FEATURES
Authors:   Perm State University, Vetoshkina Ekaterina E. , Baleva Milena V. ,   Perm State University
Published: August 2022

The paper deals with the problem of determining the zones of predictive accuracy of everyday perception. We studied implicit representations of women about the satisfaction with marriage among males with contrasting personality traits. The research involved 100 females aged from 17 to 48 (M = 22.11, SD = 4.23). At the first stage, the respondents filled out the Big Five-2 questionnaire. After that, they studied the responses to the same questionnaire supposedly given by a man with one of the four traits viv-idly expressed: extraversion, introversion, benevolence, or hostility. The participants were then asked to fill out the Marriage Satisfaction Questionnaire in the way they thought this man would do it. The data were analyzed using ANOVA. It was found that women attribute the same level of satisfaction with mar-riage to extroverted and introverted men. These judgments appear to be based on a projection mechanism, which is manifested in the fact that subjects with high extraversion predict a more successful marriage for an extrovert, and introverted subjects attribute an equally successful marriage to both an introvert and an extrovert. Thus, taking the projective intervention into account, it can be concluded that the implicit theo-ry of the extraverted personality is consistent with research data on links between extraversion and sub-jective well-being. Women also ascribed significantly higher marital satisfaction to the benevolent men than to the hostile ones. This indicates that the implicit theory of benevolent personality does not repro-duce the objective variability of interpersonal interaction scenarios of such a personality. The results ob-tained expand the understanding of the implicit theories limitations and can be helpful in preventing cog-nitive distortions in the field of social perception.
STUDY OF THE CORROSION PROCESS OF A PEO-TREATED ALUMINUM ALLOY IN DIFFERENT CONCENTRATIONS OF NaCl
Authors: Shi Yuanji , Dai Yunzhong , Gao Guoqiang , Cheng Cheng , Song Yunyun
Published: August 2022

Plasma electrolytic oxidation (PEO) treated ceramic coatings were formed in silicate-based electrolytes without and with the addition of Al2O3, on an aluminum alloy. It was found that the coating produced in an electrolyte containing 7 g/L of Al2O3 exhibited the most superior corrosion properties. The corrosion properties of the coatings in 0.5 M and 1 M NaCl solutions were studied by means of potentiodynamic polarization and electrochemical impedance spectroscopy (EIS). The results proved that the coating can protect the substrate from the corrosion due to aggressive Cl– in 0.5 M NaCl after 384-h immersion. However, it cannot protect the substrate after 384-h immersion in 1 M NaCl solution. The potentiodynamic polarization results matched well with the EIS test results.
MOLECULAR DYNAMICS SIMULATION OF TENSILE DEFORMATION OF NANOMETER MULTILAYER Cu/Ta MATERIALS
Authors: Hu Jianian , Haotian Zhang , Youlin Zhu , Peibo Li , Guoqiang Luo , Chuanbin Wang , Qiang Shen , Lianmeng Zhang
Published: August 2022

In this research, the tensile mechanical properties and microstructure evolution of Cu/Ta nanolayered composites were studied using the molecular dynamics simulation method. By analyzing the tensile stress/strain relationship of Cu/Ta with different interface structures and the movement of dislocations during the stretching process, the deformation mechanism of materials with different interface structures and the effect of interface structures on the tensile strength of Cu/Ta nanolayered composites are revealed. The effect of shear localization during extension is also analyzed. The results show that the dislocation structures at the interfaces of Kurdjumov-Sachs-type and Nishiyama-Wasserman-type samples are parallelogram and triangular interface defect arrays, respectively, which can easily induce two Shockley partial dislocations to slide along different (111) planes, forming an intersection and merging into ladder-rod dislocations. However, dislocations between the Kurdjumov-Sachs š112ć-type sample interfaces exhibit parallel array characteristics, while the interfacial dislocations have non-planar interface components, which can induce deformation twinning. The process is dissociated through a set of intrinsic interfacial dislocations. Shockley partial dislocations are then formed by dislocation motion, creating stacking faults (SF1), and then the second set of partial dislocations may nucleate from the interface and slide on the adjacent SF1 plane, eventually forming deformation twinning.
CONTEMPORARY TECHNOLOGIES FOR THE MEASUREMENT OF PULPAL BLOOD PERFUSION IN TEETH
Authors: Birk Leja , Nemeth Lidija , Cankar Ksenija , Birk Luka
Published: August 2022

Pulse oximetry (PO) and laser-Doppler fluxmetry (LDF) can be used for a determination of tooth vitality by measuring the pulpal blood perfusion. They offer an alternative to conventional pulpal sensibility tests, which evaluate only the pulpal sensory function. The aim of the study was to conduct vitality and sensibility tests on permanent caries-free and carious teeth with different degrees of caries progression and compare the results. In the clinical study, 230 permanent teeth from 25 adult subjects were tested with two conventional pulpal sensibility tests (electric, cold) and two novel pulpal vitality tests (PO, LDF). Carious lesions were detected and assessed using the criteria of the International Caries Detection and Assessment System (ICDAS). In the further statistical analyses, pulpal oxygenation levels and LD flux values were compared between the carious and caries-free teeth. The degree of agreement between the sensibility and vitality tests was also evaluated. Both methods proved reliable for a determination of pulpal vitality with their consistent readings on the teeth. Carious teeth had significantly lower PO values than non-carious teeth (p < 0.05). The degree of agreement between the tests of vitality and sensibility was fair to poor (κk < 0.40), which confirmed the thesis that further clarification of their relations is needed. PO and LDF proved useful in the evaluation of the pulpal tissue function by enabling the assessment of pulpal blood supply.
A new threat is on the horizon: The monkeypox virus. Should we worry about it or just keep an eye on it?
Authors: Gastón Sanglier Contreras
Published: August 2022

Monkeypox is a rare viral disease that is endemic in many African countries. However, within days, dozens of cases of monkeypox were confirmed in at least 12 non-African countries. It first appeared in the UK and was reported on 7 May 2022. The discovery of the virus in many patients and in different populations around the world within a few days raised the issue of scientific, medical, managerial, and social logic. The cases reported to date have no established travel links to endemic areas, but a recent mass event may have served as a focus for amplification. Epidemiological investigations are ongoing. With increased surveillance in non-endemic countries, it is likely that more cases of monkeypox will be identified and confirmed. With all this, we must ask ourselves, as we did with the advent of COVID-19, whether the population is seriously threatened and whether or not we should be concerned about the new virus in the future.
Welfare Mediators as Game Changers? Deconstructing Power Asymmetries Between EU Migrants and Welfare Administrators
Authors: Ratzmann Nora , Heindlmaier Anita
Published: August 2022

Under EU law, EU citizens constitute a particular group of immigrants, as they can, mostly without restrictions, move to, and reside in, another EU country, enjoying equal treatment with nationals in terms of accessing employment and social rights. However, as this article demonstrates, the settlement of EU citizens in another member state does not happen without hurdles. Through a careful in‐depth study of access to transnational welfare rights in practice, we analyse knowledge and resulting power asymmetries impacting interactions between certain EU migrant claimants and street‐level bureaucrats in Austrian and German social administrations. Following an inductive approach, based on an extensive data set of 144 qualitative interviews, this article first unpacks the different types of knowledge asymmetries relating to administrative procedures, formal social entitlements and the German language. We then analyse how such knowledge asymmetries may open space for welfare mediation in order to compensate for a lack of German language skills and to clarify misunderstandings about legal entitlements and obligations embedded in the claims system. Finally, our contribution offers a typology of welfare mediators and their characteristics, as not all types can be regarded as equally effective in reshaping power asymmetries. Overall, this article allows for insights into how welfare mediators, as more or less institutionalised opportunity structures, can shift policy outcomes in unexpected ways, enabling access to social benefits and services for otherwise excluded EU migrant citizens working, or seeking to work, in another EU member state.
A Systematic Approach to the Methodology of Typhlopedagogy on the Example of Mathematical Analysis Problems
Authors: Kulanin Y.D. , Stepanov M.E. , Panfilov A.D. , Potonyshev I.S.
Published: August 2022

The article discusses some of the problems that arise when working with students with visual defects. In particular, the authors discuss ways to improve the culture of mathematical thinking of students with visual defects. The authors rely on the experience of working at the Faculty of Information Technologies of Moscow State Moscow State University of Psychology & Education.