bluuebunny/crossref_metadata_2025 huggingface dataset:
Electrochemical Behavior of Plasma Nitrided Austenitic Stainless Steel in Chloride Solutions
Authors: Zatkalíková Viera , Drímalová Petra , Balin Katarzyna , Slezák Martin , Markovičová Lenka
Published: July 2024

The application possibilities of austenitic stainless steels in high friction, abrasion and sliding wear conditions are limited by their inadequate hardness and tribological characteristics. In order to improve these properties, thermochemical treatment of their surface by plasma nitriding is suitable. This article is focused on corrosion resistance of the conventionally plasma nitrided AISI 304 stainless steel (530 °C, 24 hours) in 0.05 M and 0.5 M sodium chloride solutions at room temperature (20 ± 3 °C), tested by potentiodynamic polarization and electrochemical impedance spectroscopy. The optical microscopy, scanning electron microscopy, energy-dispersive X-ray spectroscopy and X-ray photoelectron spectroscopy are used for the nitrided layer characterization. The experiment results point to a significant reduction in corrosion resistance after performed plasma nitriding even in a solution with a very low chloride concentration (0.05 mol/L).
Vegetarian diets in children: the modern view
Authors: Nalyotov А.V. ,   M.Gorky Donetsk State Medical University, Donetsk, Russian Federation, Marchenko N.А. , Khavkin А.I. , Makhmutov R.F. ,   M.Gorky Donetsk State Medical University, Donetsk, Russian Federation,   Research Clinical Institute of Childhood, Ministry of Health of the Moscow Region, Moscow, Russian Federation,   Belgorod National Research University, Belgorod, Russian Federation,   M.Gorky Donetsk State Medical University, Donetsk, Russian Federation
Published: July 2024

The scientific review of vegan nutrition for children and adolescents includes links to position papers from various scientific professional organizations in the field of nutrition and pediatrics. Over the past two decades, specialized associations have issued official statements and published position papers on the possibilities of following vegetarian diets at various stages of human life, including pregnancy and lactation, infancy and childhood. Some of these associations strongly support the idea that a well-thought-out vegetarian diet can be adequate in terms of the composition of the nutrients obtained, and support the normal growth and development of the child. At the same time, special attention is paid to careful diet planning, implementation of the necessary vitamins and microelements, regular medical and dietary monitoring. At the same time, some pediatric associations warn against the use of a vegan diet in children and adolescents, citing the potential harm and lack of high-quality clinical studies on this issue. The review presents the results of modern studies comparing the nutritional adequacy of vegetarian diets and traditional nutrition in childhood. Key words: restrictive types of nutrition, vegetarian diets, veganism, children, nutrient supply, position papers
Analysis of long-term treatment outcomes for diffuse peritonitis in children
Authors: Zavyalkin V.A. ,   Samara State Medical University, Samara, Russian Federation, Barskaya M.A. , Kuzmin A.I. ,   Samara State Medical University, Samara, Russian Federation,   Samara State Medical University, Samara, Russian Federation
Published: July 2024

Objective. A research objective was the analysis of the remote results of treatment of the widespread purulent peritonitis at children which is carried out by means of the adequate optimized pathogenetic therapy and the active medical examination including prevention of an adhesive disease of an abdominal cavity and correction of dismetabolichesky frustration. Materials and methods. The research is based on the analysis of treatment 339 with widespread peritonitis of various etiology in 17 years (from 2006 to 2017). Children depending on the treatment performed at them were divided into two groups – the main and control. In the main group (237 children) the patients with widespread peritonitis received treatment according to the offered advanced complex strategy. The control group (102 children) was made by children with widespread peritonitis at whom it was carried out traditional complex therapy according to the standard approaches. The research of the remote results of treatment of widespread peritonitis at 142 children is conducted that made 42.88% in the studied groups. At 92 children who had widespread peritonitis the development of symptoms of endothelial dysfunction at an extract is investigated and in the remote period, at 69 patients of both groups the endothelial dysfunction is studied in 3, 6, 12 months, 4 and 7 years. The remote results of a physical condition of the children who had widespread peritonitis with existence or lack of an asthenic syndrome, dispepsichesky frustration, signs of various forms of an adhesive disease are analyzed. The directed treatment of endothelial dysfunction by the medicine Reamberin® and a gepatoprotektor Remaksol®, according to indications – application veno-venous hemodiafiltration was carried out. Children in this group received antiadhesive therapy with use of SMT, fonoforez with collagenases on an anterior abdominal wall and kuprenit inside. Treatment was carried out by courses and after the patient's extract from a hospital. Patients after an extract received bile-expelling medicines (Hofitol within 14 days), eubiotik (Hilak-Forte, Buck-Seth) within 1 month and an endothelial protector (Cytoflavin®). Results. Analyzing the remote results of treatment of children with widespread peritonitis, we revealed higher efficiency of sovershenstvovanny complex treatment of this disease. At the same time it was succeeded to achieve increase in the good remote results of treatment in the main group more than twice in comparison with patients of control group. Conclusions. All above demonstrates more favorable quality of life of the children who received complex treatment of widespread peritonitis according to the strategy developed by us. Key words: widespread peritonitis, endothelial dysfunction, rehabilitation, children, Reamberin, Remaksol, Cytoflavin
Features of the duration of COVID-19 pneumonia in children under three months of age
Authors: Bairashevskaia A.V. ,   I.M.Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russian Federation, Aminova A.I. , Eryushova T.Yu. , Matsukatova B.O. , Pestova A.S. , Rodina S.A. , Muradova N.N. ,   I.M.Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russian Federation,   I.M.Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russian Federation,   I.M.Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russian Federation,   I.M.Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russian Federation,   I.M.Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russian Federation,   I.M.Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russian Federation
Published: July 2024

COVID-19 infection remains an actual problem in pediatric practice today. Objective. To study the features of the course of this infection in newborns and infants. Patients and methods. A retrospective cohort study included 53 children under the age of 3 months with radiologically confirmed pneumonia. All children were divided into two groups: the main COV (32 children) with confirmed coronavirus infection, and the control NCOV (21 children) without this diagnosis. When analyzing clinical symptoms (runny nose, cough, fever, nausea, vomiting, weakness, lethargy, shortness of breath), it was not possible to establish statistically significant differences. A statistically significant was revealed when comparing the symptom of diarrhea (p = 0.015). Diarrhea could be explained by damage to the dense contacts of enterocytes. Results. Patients in the COV group had leukopenia with a t value of 9.6·109/l at+ normal values of neutrophils and lymphocytes. Lung lesions were not detected at high basophil values, which suggests a protective function of basophils in toddlers. Conclusion. COVID-19 coronavirus infection in children under 3 months has not yet been sufficiently studied and characterized by non-specific symptoms. To date, data on pathogenesis and clinical manifestations in this age group remain contradictory, which requires additional research. Key words: infants, diarrhea, COVID-19, newborns, pneumonia
ANALYSIS OF INDICATOR OF RURAL DEVELOPMENT INDEX (CASE STUDY VILLAGE IN MAGELANG REGENCY 2014-2018)
Authors: Husna Dwi Nisaul , Mafruhah Izza , Ahmad Riayati
Published: July 2024

One of the target found in RPJMN 2015 – 2019 is to decrease the amount of backward village up to 5.000 and increase the amount of independent village up to 2.000. Therefore BPS and BAPPENAS issued a measuring instrument called Rural Development Index (RDI) that describes the level of progress or development of the village at a time (BPS, 2018). Magelang Regency is one of 4 regencies in Central Java which become a pilot innovation village in national level. The aims of this research are (1) to find out the description of RDI and (2) to find out the factors that influence the up and down of RDI. This research uses RDI measurement method issued by BPS and BAPPENAS in 2014. This method uses 42 indicators divided into 5 dimensions: (1) basic services; (2) infrastructure conditions; (3) accessibility/ transportation; (4) public services; and (5) governmental administration. The result shows that the RDI score in Magelang Regency in 2014 – 2018 increased even just 0,05. In 2014, RDI is at 64,24 and increased to 64,29 in 2018. Rural development is expected to empowering the community when the Rural Goverment making the development policy so it can be accordance with what the community needs.
ANALYSIS OF FACTORS INFLUENCING CONSUMER DECISIONS TO PURCHASE PRODUCTS
Authors: Najib Alif Fathurrahman , Istiqomah Nurul , Setiawati Untari Eka
Published: July 2024

Entertainment is an industry that is in great demand by humans today. The entertainment industry itself has many derivative industries accompanying its development. The toy industry is one of the derivative sectors that have become a commodity that is reasonably considered. This study aims to analyze the factors that can encourage consumers to make purchasing decisions on toy products, especially from Bandai. The analysis was conducted using independent variables in product quality, product image, price perception, income, and age of consumers. The dependent variable used is the purchase decision on Bandai's toys. The samples used in this study are those who bought or did not buy Bandai's toys and live in Surakarta. The study uses analysis methods with logistic regression. The study results show that to get a higher profit, Bandai can strengthen the image of its products. Maintaining the product image can be done with product introductions through exhibitions or advertisements. In this case, introducing the product through the screening of television series and films is more appropriate because the Bandai toys are derived from related entertainment industry products. The screenings will result in an attachment between consumers and toy products made by Bandai and are expected to encourage consumers to make purchasing decisions.
IMPACT OF OVO DIGITAL WALLET ON MSME WELFARE IN SURAKARTA
Authors: Ramadhan Fabian Kusuma , Suryantoro Agustinus , Nihayah Dyah Maya
Published: July 2024

This study examines the impact of using the OVO digital wallet on the turnover of street vendors in Surakarta. The informal economy, particularly street vendors, plays a significant role in Indonesia's economy. This research utilizes multiple linear regression analysis on questionnaire data to understand the influence of OVO usage. Findings indicate that OVO usage increases vendor welfare through higher income turnover, supported by the ease of use, mobility, reputation, trust, and security of the fintech product. Jebres, with its large number of vendors around Sebelas Maret University, shows significant influence.
STRATEGIC PROJECT MANAGEMENT DEVELOPMENT UNDER INFLUENCE OF ARTIFICIAL INTELLIGENCE
Authors: Bushuyev Sergey , Bushuyev Denis , Bushuyeva Victoria , Bushuyeva Nataliia , Tykchonovych Yuri
Published: July 2024

This paper explores the dynamic intersection of artificial intelligence (AI) and strategic project management (SPM), investigating the transformative effects of AI technologies on traditional project management practices. As organizations navigate an increasingly complex and fast-paced business environment, the integration of AI in SPM emerges as a catalyst for efficiency, adaptability, and informed decision-making. The study delves into key facets of SPM influenced by AI, including data-driven decision-making, predictive analytics, automation of routine tasks, and resource optimization. The role of AI in risk management, particularly in identifying, assessing, and mitigating project risks, is examined in detail. Furthermore, the paper explores how natural language processing (NLP) fosters enhanced communication within project teams, contributing to a more collaborative and connected working environment. Adaptive project planning, facilitated by AI, is investigated as a mechanism for responding to evolving project dynamics in real-time. The paper underscores the importance of continuous monitoring and reporting enabled by AI, providing project managers with timely insights for strategic adjustments. The concept of continuous improvement, driven by AI-driven analytics, is explored as organizations seek to refine and optimize their project management approaches based on past experiences. Ethical considerations and responsible AI practices are emphasized as integral components of AI integration in SPM. The paper concludes by highlighting the synergistic potential of human expertise and AI capabilities, envisioning a future where organizations can leverage AI to achieve more adaptive, efficient, and successful project outcomes. This comprehensive review aims to contribute to the understanding of AI's transformative influence on strategic project management, providing insights for practitioners, researchers, and organizations seeking to navigate the evolving landscape of project management in the era of artificial intelligence.
PROJECT MANAGEMENT MODELS FOR DEVELOPMENT PROJECTS IN SELF-MANAGED ORGANIZATIONS IN A SYNCRETIC CONTEXT
Authors: Bushuyev Sergey , Ivko Andrii
Published: July 2024

The relevance of developing models and methods of syncretic management for development projects of self-managed organizations is justified. The practical value of such models for infrastructure restoration projects in Ukraine is emphasized. The methodological approach of syncretic management to the implementation of infrastructure restoration projects was proposed, an analysis of the environment for the implementation of development projects of self-managed organizations was carried out, including the characteristics of the environment of the management models of development projects, suitable models of the life cycle of development projects and the main elements of the self-managed approach for use in the studied projects. Three characteristics of the life cycle model for development projects of self-managed organizations are defined, and a four-phase model is proposed: initialization, implementation, testing, and closure. The main elements of the self-managed approach were identified for use in the studied projects, consisting of seven such elements: the use of the principle of self-management, collegial decision-making, the absence of a formal leader, the assumption of responsibility by members of a self-managed team, self-determination of motivation, the use of holacracy models and methods, independent development of competence by participants teams Two models were proposed - α-model and β-model of management of development projects of self-managed organizations in a syncretic context. Visualization of the specified models, their description and comparative characteristics were provided. In the development of this approach, a complex model of management of development projects of self-managed organizations was also formalized in a syncretic context, in the form of a formal eight using set theory. a SWOT analysis of the proposed models was carried out, their strengths and weaknesses, opportunities and threats that may arise as a result of their use were highlighted. A conclusion was made based on the results of the SWOT analysis. Prospects for further research in the chosen direction were formulated. It was determined that the qualified implementation of the mentioned developments in the practice of infrastructure restoration projects will potentially increase the effectiveness of such projects and portfolios of such projects.
Pengintegrasian Nilai Gotong Royong Melalui Model Teams Games Tournament pada Mata Pelajaran Pendidikan Pancasila di Sekolah Menengah Pertama
Authors: Prasetyo Girimbang Wahyu , Desvania Nur Rini Tri , Japar Muhammad
Published: July 2024

The purpose of this study was to determine the implementation process and the cultivation of the value of gotong royong through collaborative learning type Teams Games Tournament (TGT) in the subject of Pancasila Education in junior high school. This research uses a qualitative approach with descriptive methods. Primary data sources were obtained through six student informants in class VIII, one key informant of Pancasila Education teacher. While secondary data were obtained through literature study and documentation. The data collection procedures carried out in this study were observation, interviews, and documentation. The findings in this study show that Pancasila Education teachers use Teams Games Tournament (TGT) type collaborative learning to instil the value of gotong royong to students. Then, when collaborative learning of Teams Games Tournament (TGT) type takes place, learners in their groups show: Firstly, caring for group members who have difficulties. Second, learners are aware of their abilities. Third, learners are able to interact and discuss well. Fourth, group members are able to co-operate well. Fifth, responsibility for the division of tasks obtained from the learning group.
 
Abstrak
Tujuan penelitian ini adalah untuk mengetahui proses pelaksanaan dan penanaman nilai gotong royong melalui pembelajaran kolaboratif tipe Teams Games Tournament (TGT) pada mata pelajaran Pendidikan Pancasila di SMP. Penelitian ini menggunakan pendekatan kualitatif dengan metode deskriptif. Sumber data primer didapatkan melalui enam informan peserta didik kelas VIII, satu key informan guru Pendidikan Pancasila. Sedangkan data sekunder diperoleh melalui studi kepustakaan dan dokumentasi. Prosedur pengumpulan data yang dilakukan pada penelitian ini adalah observasi, wawancara, dan dokumentasi. Temuan dalam penelitian ini menunjukkan bahwa guru Pendidikan Pancasila menggunakan pembelajaran kolaboratif tipe Teams Games Tournament (TGT) guna menanamkan nilai gotong royong kepada peserta didik. Kemudian, ketika pembelajaran kolaboratif tipe Teams Games Tournament (TGT) berlangsung, peserta didik di dalam kelompoknya menunjukkan: Pertama, peduli terhadap anggota kelompok yang mengalami kesulitan. Kedua, peserta didik sadar akan kemampuan yang dimilikinya. Ketiga, peserta didik mampu berinteraksi dan berdiskusi dengan baik. Keempat, anggota kelompok mampu melakukan kerjasama dengan baik. Kelima, tanggung jawab terhadap pembagian tugas yang didapatkannya dari kelompok belajar.
The Foundations of Royal Power in Early Medieval Germany: Material Resources and Governmental Administration in a Carolingian Successor State. By David S. Bachrach. Woodbridge: Boydell, 2022. ISBN 978-1-783-728-5 (hb). xix + 364 pp. £75 ISBN 978-1-800-10633-8 (ePDF). xix + 364 pp. £24.99
Authors: Nash Penelope
Published: July 2024

Review of: David Bachrach, The Foundations of Royal Poer in Early Medieval Germany: Material Resources and Governmental Administration in a Carolingian Successor State, (Woodbridge: Boydell, 2022).
The Idea of Humanity in Kant’s Categorical Imperative
Authors: Gadzhikurbanov Aslan G. ,   Lomonosov Moscow State University
Published: July 2024

Kant’s categorical imperative is associated with a type of moral act that endows it with some self-sufficiency, an objective necessity in itself without defining any goal. The peculiar aimlessness of a moral act becomes its important distinguishing feature. The definition of the moral principle in terms of the teleology of an inherently valuable act of moral will is directly related to the version of the categorical imperative that we are considering. In it, every person (as a rational being and a representative of the idea of Humanity) to one degree or another turns out to be a priority object of the practical application of the categorical im­perative, since it is considered as an intrinsically valuable entity, or a goal in itself. The uni­verse of Kant, or the world of nature, is a highly expedient device, the ultimate goal of which is man as a moral being. The status of man as the ultimate goal of nature opens up a new perspective for him – the acquisition of a supersensible status and moral freedom. In this property, a person is already designated by Kant as a “noumenon”. In the version of the categorical imperative that we are considering, Kant actually declares that the exclus­ive goal of the moral aspiration is not just a person, but humanity (Menschheit), which the individual “in his own person” or “in the person of any other” only represents. He also calls it the intelligent world (mundus intelligibilis). Man as a moral being is so valuable that one can see in him the ultimate goal of nature and the goal in himself. What makes him so is his belonging to a higher reality, to the realm of ends, or to Humanity as such. Kant takes one more step, elevating Mankind and moving from the moral to the religious space. He turns Humanity into a sacred thing.
New Books
Authors: Vakulinskaya Alexandra ,   RAS Institute of Philosophy, Vorozhikhina Ksenia , Kuksyuk Alexey , Makarova Anna , Sidorin Vladimir ,   RAS Institute of Philosophy,   RAS Institute of Philosophy,   RAS Institute of Philosophy,   RAS Institute of Philosophy
Published: July 2024

The collective material of the employees of RAS Institute of Philosophy (A. Vakulinskaya, K. Vorozhikhina, A. Kuksyuk, A. Makarova, V. Sidorin) describes the book novelties of 2023 related to topics of Russian philosophy. Brief summaries present the main content of the books - thus, the reader is able to get acquainted with the most important and interesting publications, including: “Civilization: The Polyphony of Meanings. Memoria”; “Solowjew” by H. U. von Balthasar; “We will be Faces/Persons… An Analytical-Synthetic Reading of Dostoevsky’s Works" by T. Kasatkina; Volume 7 of E. Ilyenkov's Collected Works ; Volume 5 of S. Frank's Collected Works; “My Zinoviev” by A. Guseinov; “Nikolai Berdyaev: an Epistolary Conversation. Archival Materials” ed. By T. Shchedrina; collective monograph "Sergei Nikolaevich Trubetskoy”; “Eurasianism: Logos. Eidos. Symbol. Myth” by R. Vakhitov; Anthology “The Сement and Body of Russian Socialism”.
About Vasily Rozanov As a Publicist. Review on: «“Rozanov was not hypocritical, he was two-faced...”: Vasily Rozanov as Publicist and Polemicist» by Natalia Kazakova (Moscow, 2022)
Authors: Teslya Andrei ,   Research Center for Russian Thought Institute for Humanities. Immanuel Kant Baltic Federal University
Published: July 2024

The essay examines the latest book by Natalia Yurievna Kazakova «“Rozanov was not hypocritical, he was two-faced...”: Vasily Rozanov as Publicist and Polemicist», published in 2022 by Russian State University for the Humanities. Kazakova's book is both a study of insufficiently explored aspects of Vasily Rozanov's journalistic work and a survey (with the aim of providing an initial introduction to the subject) of his persona as a journalist, and also includes a carefully commented publication of Rozanov's letters to S.P. Kablukov, dated October-November 1918 (and now preserved in the Bakhmeteff Archive at Columbia University, New York). In addition to the appendix (in which the letters to Kablukov are published), the book consists of an introduction, a conclusion, and four chapters. The first chapter deals with general characteristics of Rozanov as a journalist; the author presents a kind of «parallel biography» of Rozanov and A.S. Suvorin, and describes Rozanov's relationship with the editors of “Russkoe Slovo”, the second major national newspaper after “Novoe Vremya”; Rozanov was associated with “Russkoe Slovo” for a long time, but not publicly (unlike his cooperation with “Novoe Vremya”). The following two chapters are organized chronologically: the second chapter analyzes the significance of his ideological predecessors for Rozanov (A.S. Khomyakov, N.N. Strakhov, and K.N. Leontiev) and Rozanov's first great debates (with N.K. Mikhailovsky and V.S. Solovyov), and in the third chapter the author considers Rozanov’s polemics with his contemporaries, where Rozanov appears as an «equal value». The final chapter is devoted to Rozanov's interpretation of various themes related to 19th-century Russian literature and describes his general perception of Russian classical literature and its complete image that Rozanov creates. The book concludes with a brief thoughtful analysis of Rozanov's “Apocalypse...”, in which he summarizes the main themes of his entire publicist and philosophical
Who are the Gordin Brothers? (based on archival documents of the YIVO Institute for Jewish Research in New York City)
Authors: Gerasimov Nikolai ,   Aleksandr Solzhenitsyn House of Russian Expatriates
Published: July 2024

The article deals with the biographies of Wolf and Abba Gordins and with the problem of authorizing their works. According to the author, the modern academic community should focus not only on the reception of Gordins’ ideas, but also on compiling their bibliography. The article consists of: 1. The text, in which the author reveals the historical and philosophical difficulties in the study of the Gordin brothers’ heritage. 2. The biographical note found at the YIVO Institute for Jewish Research in New York city, which reveals the main milestones of the social and political (anarchism) and creative life of Gordin brothers, as well as indicating which of the philosophical and artistic works were written collectively. In the commentary on the bibliography, the author clarifies errors and inaccuracies in the text of whoever compiled this bibliography.
Infection of Gastro-intestinal Parasites in Native Chicken (Gallus domesticus) in Sub-district of Kupang Tengah, Kupang Regency
Authors: Seran Hildegardis Hoar , Almet Julianty , Raja Mangihut Ronael Simata Yohanes Timbun , Lestari. Djungu Dewi Fesbayati , Winarso Aji
Published: July 2024

Rural communities in Kupang Regency generally raise native chickens as an additional income. The rearing of native chickens in Kupang Regency is still mostly in the form of extensive farming, making them vulnerable to parasitic infections. Parasitic infections in native chickens lead to decreased productivity. This study aimed to determine the prevalence and degree of gastro-intestinal parasite infection in native chicken (Gallus domesticus) in Sub-district of Kupang Tengah, Kupang Regency. A total amount of 56 fecal samples were collected from native chicken in 4 villages. Fecal samples were examined using the McMaster and sedimentation methods. This research found 5 types of endoparasites that infect native chickens in Sub-district of Kupang Tengah, namely: Ascaridia galli, Heterakis gallinarum, Trichuris sp, Railletina sp. and parasitic Protozoa (Eimeria spp). The degree of endoparasite infection in chickens in Central Kupang District was: Nematodes (Ascaridia galli and Heterakis gallinarum) were categorized as moderate infection, and Trichuris sp was included in the category of mild and severe infection. While in the class of Cestoda (Railletina sp) and Protozoa (Eimeria sp) were included in the category of mild infection
Anatomical and Functional Results of Patients with Late-Stage Age-Related Macular Degeneration Implanted with the Smaller-Incision New-Generation Implantable Miniature Telescope (SING IMT™)
Authors: Adamo Ginevra , Pellegrini Marco , Nasini Francesco , Talli Pietro Maria , Sarti Laura , Perri Piera , Parmeggiani Francesco , Mura Marco
Published: July 2024

Objectives
The aim of the study was to evaluate anatomical and functional outcomes of the Smaller-Incision New Generation Implantable Miniature Telescope (SING IMT™) in patients with bilateral advanced age-related macular degeneration (AMD).
Methods
This non-comparative retrospective single-surgeon interventional case series included patients with bilateral late-stage AMD who underwent cataract surgery and SING IMT™ implantation at the Sant’Anna University Hospital, University of Ferrara, Italy. The main outcome measures included corrected distance (CDVA) and near visual acuity (CNVA), endothelial cell loss (ECL), and incidence of complications.
Results
11 eyes of 11 patients were included. The mean follow-up duration was 6.5 ± 2.4 months. After surgery, CDVA significantly improved (from 17.00 ± 9.74 to 26.00 ± 8.53 letters (P = 0.008). Significant improvement of CNVA was also observed (from 12.27 ± 4.36 to 8 ± 2.61 Jaeger levels; P = 0.004). Mean ECL was 4.8 ± 5.5% at 3 months. No intraoperative complications were observed, while postoperative complications included iris incarceration (9.1%), pigment deposition on the device (9.1%), and transient corneal edema (27.3%). Nevertheless 10 of 11 patients (90.9%) began to complain of blurred or hazy vision within 3 months of surgery. The device was ultimately explanted in 3 patients (27.3%) because of this symptom.
Conclusions
Although SING IMT™ implantation is associated with promising objective results, unexplained blurred or hazy vision represent common postoperative complaints which may lead to patient dissatisfaction. Further studies including patient reported outcomes are warranted to evaluate the effect of the intervention on patients’ visual function and quality of life.
A Comprehensive Study on Seismic Site Characterization and Liquefaction Susceptibility Assessment (LSA) through Multi-channel Analysis of Surface Wave (MASW)
Authors: Patel Neelu , Ahamad Md Naseem , Singh Vishwajeet Pratap
Published: July 2024

Multi-channel Analysis of Surface Waves (MASW) is a seismic exploration technique first introduced in geophysics by CB Park in 1999. It assesses sub-surface ground stiffness by measuring shear wave velocity (Vs) in 1D, 2D, and 3D applied in diverse geotechnical engineering projects within the most common depth ranging from 0 to 30 meters. This non-intrusive seismic technique is widely used to draw out the Vs profile which illustrate the variation of soil velocity with depth. This paper details a novel approach to enhance the integration of MASW to seismic site characterization as per National Earthquake Hazard Reduction Programme (NEHRP) and Liquefaction Susceptibility Assessment (LSA) of seismically active 6 sites of Deoria district, Uttar Pradesh, these sites are situated very near to the seismically active Himalayan belt, which is vulnerable to great earthquake. Liquefaction poses a significant threat demanding accurate sub-surface characterization of seismically active sites. Seismically active sites seek to evaluate site-specific LSA by understanding local geologic, compositional, state, and historical criteria. MASW survey at all 6 locations was conducted by using a 24-channel PASI seismograph and 24 numbers of vertical geophones (natural frequency 4.5 Hz) situated at 2.0m intervals. A steel sledgehammer (15 kg) strikes on a steel plate to generate seismic waves. To develop and invert the surface wave seismic data to develop 2D depth versus Vs profiles, ZondST2D software was used. The average Vs30 of the current study area was found in between 158–370 m/s. Based on Vs30 seismic site characterization has been carried out. It was found that most of the sites fall in site class D. Some of the sites fall in site class DE as per NEHRP 2020 site classification. During Liquefaction Susceptibility Analysis (LSA), it was observed that most of the sites exhibited susceptibility to liquefaction up to a depth of 5.0 to 10.0 meters from the ground surface. The classification helped a preliminary understanding of the liquefaction susceptibility of sites chosen for the various geotechnical engineering projects.
Alignment of the surface seep from the groundwater bearing zones to the near surface vegetation’s at the Nubutautau Village in Fiji
Authors: Maharaj Ronald , Kumar Sushil , Rollings Nicholas , Singh Shailesh Kumar
Published: July 2024

Groundwater interaction with the surface topological features are interactive based on the internal flow movement and the directions. Parameters such as transmissivities conducti vies and permittivity’s govern the near surface point seepages which leads the near surface topological features in the form of the sharp vegetations and creeks. The movement of the water may be dictated by the slopes, soil porosity, soil drainage and the membrane of the rocks that lie within the aquifer and the adjacent zones. The inner water movement draws vegetation features which may be visible and significant on the satellite imagery in the form of the sharp boundaries, geological areas and the dikes. Ground water exploration works has been carried out in the Village of Nubutautau within Fiji through the detection of underground aquifers with the usage of the Geophysical techniques. An interesting feature of the water zones with the near surface topological feature has been observed.
Monitoring Heavy Metals in e-Liquids upon Vaping using Nano-Magnetic Graphene Oxide Extractor with ICP-OES Detection
Authors: Abdelghani Jafar , Khwara Moayad A. , El-Sheikh Amjad H.
Published: July 2024

In the last few years, electronic cigarette has quickly increased. In evaluating their safety, and in view of upcoming guidelines, toxic heavy metals are the most potential to be monitored in the liquids of electronic cigarette (e-liquids). A sensitive analytical method using magnetic-graphene oxide extractor and inductively coupled plasma with optical emission spectroscopy (ICP-OES) was developed and validated to measure the levels of seven heavy metals in twenty five e-liquids from a local brand. Extraction of heavy metals by magnetic-graphene oxide had concentrated the level of metals and reduced the significant matrix effect generated from other e-liquid constituents. Regardless the lack of reference materials for e-liquids, the developed method demonstrated high linearity, precision, and allowed the quantification of low levels of heavy metals with quantification limit < 85 µg/L for Ni, Hg, Cd and Co. For the examined e-liquids, analysis indicated that the results were not normally distributed and presence of many outliers, hence, median value was more convenient than average value to evaluate the existence of heavy metals in the samples. The highest level of metals in unused e-liquids was reported for Cu, Cr, and Ni with average values of 2.51, 5.64 and 8.60 µg/g, respectively. Upon vaping, the level of Ni and Cu were increased by 2 and 37 folds, respectively, in the remaining liquid mainly due to contact with the device coil. Although there are no local or international standards on the quality of e-liquids, the proposed analytical method is transposable for official laboratories responsible for the quality of regular and electronic cigarettes.
Clinical characteristics and early diagnosis of pituitary abscess: a review of twenty-four cases
Authors: Wang Xuan , Xie Wentao , Ye Zhen , Liu Qihui , Ye Zhao , Li Ning
Published: July 2024

Objectives Pituitary abscess (PA) is a rare disorder and preoperative diagnosis is difficult. This study aims to better understand the clinical manifestations, early diagnosis, and appropriate treatment of PA.Methods This study enrolled 24 Chinese patients who were referred to Huashan Hospital, Fudan University, China, from June 2016 through December 2020, and diagnosed as PA. Their medical records were retrospectively analyzed.Results The most common clinical manifestations were amenorrhea (83.3%), male hypogonadism (66.7%), headache (66.7%), and visual disturbances (58.3%). Anterior pituitary hypofunction was commonly seen in 87.5% of them. Positive pathogenic detection was obtained in 33.3% of the patients through smear, culture and metagenomic next generation sequencing (mNGS) of CSF and pus. Rim enhancement on magnetic resonance imaging (MRI) and hyperintense on diffusion-weighted imaging (DWI) were revealed in 47.6% and 83.3% of our patients respectively. Most of the patients underwent transsphenoidal sinus surgery, accompanied with postoperative anti-infective and hormone replacement therapy.Conclusions In patients with symptoms associated with hypopituitarism, with typical rim enhancement on MRI and DWI hyperintense, the possibility of PA should be considered. Comprehensive pathogenic detection of CSF and pus were needed, and the application of mNGS may enhance the preoperative diagnostic rate. Anti-infection treatment is highly recommended after transsphenoidal sinus surgery.
Impaired Functional Connectivity of Cortico-Amygdala Pathway Can Drive Social Behavior Deficits in Synucleinopathies
Authors: Chu Hong-Yuan , Zhou Wei , Daniels Samuel , Singh Vijay , Menard Marissa , Galvis Martha L Escobar
Published: July 2024

The small molecule protein α-synuclein forms insoluble aggregates in a group of neurological disorders, including Parkinson’s disease and dementia with Lewy bodies (DLB), which are collectively called synucleinopathies. In PD and DLB, the amygdala has been identified as a particularly susceptible region in the brain for the deposition of Lewy-like α-synuclein aggregates. Though α-synuclein aggregation is closely associated with neurodegeneration, there is a poor correlation between neurodegeneration in the amygdala and the clinical features of PD/DLB. We hypothesize that, prior to neurodegeneration, α-synuclein aggregation disrupts functional cortical modulation of the amygdala circuits, leading to emotion dysregulation in synucleinopathies. In the present study, we combined electrophysiology, optogenetics, mouse model of synucleinopathies, and behavioral analysis to test this hypothesis. Using an α-synuclein preformed fibrils (PFFs)-based mouse model of synucleinopathies, we reported dynamic changes in the levels of α-synuclein pathology in the basolateral amygdala (BLA). Such dynamic changes of pathology associated with a decreased cortico-BLA connection strength prior to a significant loss of cortical axon terminals. In parallel to the reduced cortico-BLA connection, PFFs-injected mice manifested impaired social preference behavior. The impaired sociability of PFFs-injected mice could be rescued by chemogenetic stimulation of cortico-BLA inputs. Altogether, we presented a series of evidence to delineate key circuit events associated with α-synuclein pathology development in the amygdala circuits. The present work highlights the necessity of a thorough investigation of functional consequences of α-synuclein aggregation to advance our understand of pathophysiology of synucleinopathies and development of effective therapies.
A deep learning approach for deriving wheat phenology from near-surface RGB image series using spatiotemporal fusion
Authors: Cai Yucheng , Li Yan , Qi Xuerui , Zhao Jianqing , Jiang Li , Tian Yongchao , Zhu Yan , Cao Weixing , Zhang Xiaohu
Published: July 2024

Real-time image series of wheat from near-surface cameras provide high-quality data for monitoring wheat phenological stages. In this study, three deep learning models based on three different spatiotemporal feature fusion methods, namely sequential fusion, synchronous fusion, and parallel fusion, were constructed and evaluated for deriving wheat phenological stages with these near-surface RGB image series. Moreover, the impact of different image resolutions, capture perspectives, and model training strategies on the performance of deep learning models was also investigated. The results indicate that the model using the sequential fusion method is optimal, with an overall accuracy (OA) of 0.935, a mean absolute error (MAE) of 0.069, F1-score (F1) of 0.936, and kappa coefficients (Kappa) of 0.924 in wheat phenological stages. Besides, enhanced image resolution and the suitable image capture perspective introduce more effective features for phenological stage detection, thereby enhancing the model’s accuracy. Furthermore, with regard to the model training, applying a two-step fine-tuning strategy will also enhance the model’s robustness to random variations in perspective.
Toward dose-response modelling of custom-made foot orthoses: Reliability of capturing plantar foot geometry using a handheld 3D scanner
Authors: Stijn Rosseel , Matricali Giovanni , Eleonora Ferraris , Hans Hallez , Annelies Bockstael , Kevin Deschamps
Published: July 2024

Efficacy of custom-made foot orthoses (CFO) largely depends on geometric characterization and outcomes can be suboptimal due to insufficient quantitative insights thereof. Addressing this is crucial for understanding geometric characteristics in dosage-response modelling. This study evaluates the reliability of a handheld 3D scanning system for foot digitization, focusing on traditional and advanced geometric features. Two examiners used a handheld 3D scanner to capture the foot shape of thirty healthy participants in a non-weightbearing condition. Intra-tester, test-retest and inter-tester reliabilities of multiple zero-dimensional (0D) anthropometric and geometric variables were evaluated. Subsequently, the consistency of capturing the geometry of the plantar foot surface was assessed via quantification of one-dimensional (1D) anteroposterior and mediolateral plantar surface curvatures. Intraclasss correlation coefficients of the 0D parameters showed good to excellent intra- and inter-tester reliability. A pairwise comparison of the 1D curvatures showed good consistency on intra-tester level. These results demonstrated that 0D anthropometric measurements of the human foot, obtained using a handheld 3D scanning system in a non-weightbearing condition, exhibit good to excellent reliability. Additionally, the 1D curves related to the plantar surface showed high consistency, supporting its usage to quantify plantar geometry and provide insights into the role of geometric characteristics in dosage-response modelling in CFO practice.
The effects of caffeine exposure on postnatal growth in moderately preterm infants
Authors: Jones Antoinette , Trybulska Angelica , Wang Hongyue , Meyers Jeffrey
Published: July 2024

Objective:

To determine whether caffeine independently influenced linear growth during NICU hospitalization in moderately preterm infants.

Study Design:

We performed a single-center retrospective cohort study. Our primary outcome was the change in length z-score from birth to discharge or 37 weeks’ corrected gestational age (CGA). Secondary outcomes included change in weight and head circumference z-scores. Multiple regression analysis controlling for an a priori list of covariates was performed to evaluate the association between caffeine dose and the growth outcomes.

Results:

In 308 infants 29-33 weeks' gestational age, greater cumulative caffeine dose was significantly associated with a progressive decline in length (p=0.04), weight (p=0.03), and head circumference z-scores, (p<0.05).

Conclusion(s):

Caffeine exposure in moderately preterm infants has an independent dose-dependent inverse relationship with linear growth, weight gain, and head growth.
Management and Experiences in Diagnosing and Treating Acute Heart Failure in Children with Solid Tumors
Authors: Yi Zizheng , Li Xuandi , He Xiufang , Liu Juncheng , Zhu Jia , Li Shujuan
Published: July 2024

Background
To understand the characteristics and outcomes of acute heart failure (AHF) in children with solid tumors during the treatment process, share treatment experiences, and provide management strategies for monitoring, treatment, and prevention.
Methods
Five representative cases of children with solid tumors were selected to summarize the clinical features and treatment effects during the occurrence of AHF. The possible triggers and time points for the onset of AHF were analyzed, along with treatment responses and influencing factors.
Results
All five cases of children with solid tumors exhibited symptoms of AHF after chemotherapy, with heart functions staging from class II to class IV. Most cases occurred during the bone marrow suppression period with a noticeable increase in heart rate. All children received oral anti-heart failure treatment and nutritional myocardial therapy. Two children with heart function class II returned to normal after oral medication; three children with heart function class IV received intravenous vasoactive agents followed by regular reinforcement in the later stage. The heart function improved in all three cases (heart function class IV), with one case returning to normal, one case with slow recovery in noncompaction cardiomyopathy gradually approaching normalcy, and one case with only mild improvement in heart function despite concurrent renal dysfunction.
Conclusions
Children with solid tumors are susceptible to AHF during the bone marrow suppression period, and an increased heart rate serves as an early warning signal. Active anti-heart failure treatment is effective. Renal dysfunction emerging as a significant factor influencing poor recovery of heart function.
Clinical profile and Pregnancy Outcome of Acute Fatty Liver of Pregnancy in a tertiary care Teaching Hospital - A Five Year retrospective study
Authors: Puri Shreya , Jena Pramila , Tejwani Riya , Moharana Rajalaxmi , Padhee Sourav , Rath Sibanarayan
Published: July 2024

Acute fatty liver of pregnancy (AFLP) is a rare but potentially dangerous illness marked by high rates of morbidity and death in both the mother and the fetus as well as quickly developing acute liver dysfunction and liver failure. It often occurs in the first three months after giving birth or during the third trimester. Although the precise etiopathogenesis is unknown, it is believed that defective mitochondrial fatty acid metabolism is a major factor. Timely delivery and early diagnosis are essential. Usually, the illness begins with nausea, vomiting, and abdominal pain before swiftly advancing to coagulopathy, jaundice, and liver failure. Early detection and intervention are necessary for AFLP because to its high rates of maternal and perinatal mortality, even with developments in the field. The eleven patients at our institution who were diagnosed with AFLP based on Swansea criteria are highlighted in this study for their varied clinical presentations and outcomes.
Sensitive and selective fluorescent switch for Detection of Fe (III) Ion in Human urine Using luminol-functionalized Functionalized Graphene Quantum dots
Authors: Harran Noura H , alfarhani Bassam F
Published: July 2024

A fluorescent switch based on graphene quantum dots (GQDs) has been synthesized and modified using Luminol to detect Fe (III) in human urine selectively. The pyrolysis of anhydrous citric acids produced GQDs abundant in amino groups. The luminol modification shows distinct optical characteristics, improving the fluorescence intensity by approximately 6.41 times compared to GQD alone. The probe employs static quenching to initiate the fluorescence response by utilizing the interaction between Fe (III) and Luminol-GQDs, resulting in the suppression of fluorescence. The probe is capable of detecting Fe (III) in both a pure aqueous solution and synthetic urine. Furthermore, it is also able to detect Fe (III) in human urine. The concentration of Fe (III) required to quench the fluorescence intensity of Luminol-GQDs exhibits a strong linear relationship. A good linear relationship was obtained for Fe (III) concentrations ranging from 50 to 400 µM. Notably, this sensitivity surpasses that of earlier studies. The detection limit of Fe (III) using Luminol-GQDs is approximately 1.5 µM. The real sample detection was conducted using a human urine sample, and satisfactory recoveries of approximately 94.57% were achieved.