bluuebunny/crossref_metadata_2025 huggingface dataset:
Traducir la violencia. La “ley de la mayoría” en la traducción al francés de Las malas, de Camila Sosa Villada, y La virgen cabeza, de Gabriela Cabezón Cámara
Authors: Balcázar Melina
Published: March 2023

En este artículo analizo la traducción al francés de las novelas Las malas, de Camila Sosa Villada, y La virgen cabeza, de Gabriela Cabezón Cámara. Ambos textos emprenden una crítica de la violencia contra los sujetos travesti, mediante la representación de la violencia extrema y la resignificación de un lenguaje estigmatizante. El objetivo de la presente reflexión es interrogar los fenómenos de invisibilización de la violencia en las traducciones al francés de dichas novelas. ¿Qué ocurre cuando el traductor decide atenuar e incluso eliminar la violencia del lenguaje? ¿Se trata acaso de someter el texto y las sexualidades a las que da voz a lo que Gayatri Spivak llama “la ley de la mayoría”? O bien, ¿dicho borramiento de la violencia se debe a cuestiones culturales y editoriales o a una iniciativa propia de los traductores? En el texto estudio las implicaciones políticas que tales decisiones conllevan, respecto no solo a la representación de las sexualidades disidentes, sino también a la manera en que una lengua hegemónica como el francés acepta o no la expresión de una lengua periférica, en este caso, el español argentino, que voluntariamente se sitúa en los márgenes.
Production of enriched cakes by apple pulp and peel powder and evaluation of chemical, functional and textural properties
Authors: Hosseini Ahmadreza , Pazhouhandeh Fahimeh
Published: March 2023

Background: Apple pomace is a by-product of the fruit juice industry and comprises peel, seed, stem, and pulp tissues. This by-product contains dietary fiber, polyphenols, vitamins, and organic acids that can benefit human health and have a high potential as a dietary source. Baked products are well-known food types to humans and have a key role in feeding people worldwide. Nowadays, enriched products such as bread, cakes, and biscuits are available in stores. Different studies worldwide have been done about applying fruit juice industry by-products in the bakery.
Objective: This research aimed to evaluate apple peel (APE) and pulp (APU) powders separately as a partial substitute for wheat flour in cake production.
Methods: Apple peels and pulp, separately produced as residual wastes of juicing, were dried for 3 hours in the oven (60°C). The dried pulp and peel were ground and sieved using a 60 µm mesh. In this research, chemical and physic-chemical analyses were performed according to AACC (Approved Methods of the American Association of Cereal Chemists) and standard food analysis methods. Textural characteristic was analyzed by a texture analyzer (Brookfield CT3-10 Kg, US) equipped with an aluminum probe.
Results: Different levels of APE and APU powders (10, 20, and 30 %) were used to enrich the cakes. Wheat flour’s ash, fat, water, and oil absorption capacity were lower than APU and APE, whereas the moisture, protein, bulk density, and pH showed a reverse trend. Adding APU and APP to the cake formula increased total dietary fiber (TDF) from 4.14 % in the control sample to 27.71 % in the sample with 30 % apple peel powder (APE-30). The highest a* colorimetric parameter (redness) in the cake core was 3.82 in the APE-30 sample. The addition of APE and APU significantly increased the hardness, gumminess, and chewiness of the samples (p<0.05). APE-10 samples could improve the nutritional properties of the cakes without significant reduction (p>0.05) in overall acceptance compared to the control sample.
Conclusion: The results of this research demonstrated that a partial replacement of wheat flour with apple pulp and peel significantly increased the dietary fiber, especially insoluble fiber, compared to the control sample. Apple pulp powder and apple peel powder have the potential for use in cake making as a good source of dietary fiber.
Protecting Citizens against Bureaucratic Abuse and Maladministration
Authors: Ifejika Solomon I.
Published: March 2023

In 1975, with Decree No. 31, the Federal Military Government of Nigeria established the Public Complaints Commission as the country’s ombudsman institution. Charging it with the responsibility for protecting the citizen’s rights in the administration, Decree No. 31 was an enabling law to the 1974 report of the Public Service Review Panel instituted by the Military Government in 1974 to appraise and revamp the country’s public service. Following Nigeria’s return to democratic rule in 1999, the Commission’s establishment law became known as the Public Complaints Commission Act, CAP P37 of Laws of the Federation of Nigeria 2004, which sustains its existence and operation in the present Fourth Republic. Notwithstanding, the Commission’s performance has largely remained unsatisfactory for being unable to effectively deliver on its statutory mandate. This conceptual study, therefore, investigates the main factors accounting for the ineffectiveness of the Nigerian ombudsman institution. The study relies on qualitative data generated from secondary sources, which was analyzed using the thematic analysis technique of qualitative data analysis. The work finds that, among other issues, the lack of independence and legal capacity to punish offenders, are the key impediments to the effectiveness of the Commission. The study thus recommends, among other things, the amendment of the Commission’s establishment Act to grant the institution independence from the executive and legislative arms of the Nigerian Federal Government and confer on it punitive powers, as workable measures for repositioning the nation’s ombudsman institution for improved performance.
Disability and the elderly in their freedom of interaction with the spanish administration
Authors: Sánchez Ballesteros Vanesa
Published: March 2023

Disability and elderly people are considered special groups due to their high degree of vulnerability, and their welfare must be supported by public measures that reinforce the guarantees of their rights and freedoms. Although new technologies open up a world of possibilities in all areas of life, their use can hinder, in some cases, the development of the rights of these groups because their practice is a complex novelty, especially in the area of communication between citizens and the Public Administration. Therefore, this study focuses on the analysis of the impact of ICTs on the right to freedom of access of persons with disabilities and the elderly.
The Smart City and Healthy Walking: An Environmental Comparison Between Healthy and the Shortest Route Choices
Authors: Kim Eun Jung , Gong Youngeun
Published: March 2023

Walking is a means of health promotion, which is one of the main features of smart cities. A smart city’s built environment can help people choose a healthy walking route instead of the shortest one. Our study investigated which environmental factors pedestrians who select healthy routes prefer and favored environmental factors in pedestrian navigation mobile applications. Survey data were collected from 164 residents in Daegu, South Korea, from October 12 to October 25, 2022. t and chi-square tests were used to compare perceptual differences between the healthy route and the shortest route preference groups. The results indicate that 56.7% of respondents preferred a healthy walking route over the shortest route. Pedestrians who chose the healthy route preferred to have less noise and more greenery along their commute and feel safer from traffic accidents and crimes than those who chose the shortest route. Moreover, people who favored healthy routes also considered the following environmental factors in pedestrian navigation mobile applications: (a) greenery and waterfront areas, (b) low traffic volume, and (c) safety from traffic accidents and crimes. The results suggest that urban planning and design policies support healthier and more active walking in smart cities.
APPLICATION OF ARGUMENTATION IN PROCESSES DECISION MAKING
Authors:   Taras Shevchenko national University of Kyiv, Demirska Inna
Published: March 2023

Making a decision is the most important cognitive procedure that accompanies every human life and plays a significant role in the history of human culture as a whole. The entire history of mankind can, in a certain sense, be considered as the history of making certain decisions — right or wrong, rational or purely intuitive — that lead to the preservation of the existing state of affairs or to its change. However, the theory of decision-making arose and began to be developed only in the middle of the 20th century, and at first — as a theory of operations in the field of military technology. True, it was soon realized that it has a much wider application. So that at present it has turned into an interdisciplinary one that uses the methods of mathematics, psychology, sociology, political science, management and many other sciences, and is applied in various fields. Philosophical research aimed at elucidating the epistemological and logical foundations of the decision-making procedure is also being conducted in this field. The article emphasizes that a rational decision is based on a choice based not on intuition or previous experience, but on a rational analysis of the situation. Models of argumentation in decision-making are considered. The essence of logical, cognitive, and rhetorical approaches is clarified. The stages of the process of making a rational decision are explained. Conclusions. The most important difference between decision-making theory and argumentation theory is that decision-making is the basis of action/inaction in a given situation, whereas the process of argumentation is limited to substantiating a thesis/refutation of an antithesis.
Cervical Spine in Scheuermann’s Disease: Review
Authors: Mikhaylovskiy Mikhail V. , Sergunin Alexander Yu.
Published: March 2023

Background. The state of the cervical spine in patients with Scheuermanns disease has still not been studied enough. This concerns the magnitude of cervical lordosis in the norm and in juvenile kyphosis in both pre- and postoperative periods, as well as the relationship of these changes with the spinopelvic parameters. There is almost no information on the correlation between the state of cervical lordosis and the development of proximal transitional kyphosis.
Aim of the study. To determine the features of the cervical spine in patients with Scheuermanns disease in the pre- and postoperative periods by analyzing the literature data.
Results. The literature data do not allow us to clearly define the limits of normal in the quantitative assessment of cervical lordosis. The only thing all researchers agree on is that the cervical lordosis should be considered discretely, namely at the C1-C2 and C2-C7 levels. The most commonly used parameters of the cervical-thoracic junction are T1 slope, thoracic inlet angle (TIA) and position of the sagittal vertical axis (SVA).
The magnitude of cervical lordosis in Scheuermanns disease varies from 4 to 35, i.e., thoracic kyphosis increase is not always accompanied by the development of compensatory cervical hyperlordosis. In thoracic deformities (the apex is at the level of T10 and cranial), the magnitude of cervical lordosis is significantly greater than that in thoracolumbar deformities (the apex is at the level of T11 and caudal). In the first case, the cervical lordosis (C2-C7) is 19.4-26.2, while in the second one 4.7-8.5.
Very few literature data demonstrate that in terms of cervical lordosis dynamics, patients with Scheuermanns disease do not represent a homogeneous group. The only pattern is that the cervical lordosis increases slightly in the longterm postoperative period. The spinopelvic parameters in patients with Scheuermanns disease differ little from the normal ones and almost do not change after corrective interventions. We could not find any publications attempting to relate the risk of PJK to cervical-thoracic junction parameters (T1, TIA, SVA).
Conclusion. The state of the cervical spine in patients with severe forms of Scheuermanns disease, subject to surgical correction, has not been studied enough. This concerns the magnitude of cervical lordosis, its dynamics in the postoperative period, its relationship with spinopelvic parameters, as well as the correlation between parameters of transitional cervical-thoracic spine and development of proximal transitional kyphoses. Further studies of this problem are needed.
The content of chemical elements-antioxidants in the tissues of benign and malignant tumors
Authors: Lugovaya Elena A. , Ageenko Kirill I.
Published: March 2023

Background. Copper, zinc, manganese, and selenium play the role of cofactors in the enzymatic link of the antioxidant system and can be singled out as a special group of antioxidant elements. Reorganizations of the antioxidant system during carcinogenesis are reflected in the levels of these bioelements.
Aim. Analysis of the antioxidant element concentrations in benign and malignant tumor tissues and assessment of the possibility of their use as markers of neoplasms.
Material and methods. Using the methods of atomic emission and mass spectrometry with inductively coupled argon plasma, the concentrations of Cu, Zn, Mn and Se were measured in the tissues of benign and malignant neoplasms (surgical material) of 131 residents of Magadan. The objects of the study were benign neoplasia of the intestine, breast and ovary, as well as malignant neoplasia of the intestine, breast, uterus and lung. The ShapiroWilk test, the MannWhitney U test, and correlation analysis were used. Changes were considered significant at p 0.05.
Results. In a benign process, all antioxidant elements, in a malignant process, Cu and Zn turned out to be differentiating. The maximum levels of Cu, Zn, Mn and Se were recorded in benign and malignant tumors of the intestine (2.09 and 2.57; 62.99 and 22.22; 0.35 and 0.29; 0.33 and 0.30 g/g, respectively), minimal in benign and malignant breast tumors (0.58 and 0.88; 8.74 and 10.41; 0.08 and 0.19; 0.11 and 0.21 g/g). The value of the Cu/Zn ratio corresponded to the range of 0.0740.111 and significantly prevailed in cancer (p 0.05). Significant correlations (p 0.037) were recorded only in tumors of the intestine and breast and differed in multidirectional dynamics. Their number decreased in bowel cancer and increased in breast cancer.
Conclusion. Malignant neoplasms are distinguished by a higher level of antioxidant elements and atypism of the microelement profile.
A Study on the Effect of Supply Chain Risk Management of Exporting SMEs’ Operating Cold Chain Logistics System on Shipping Logistics Efficiency
Authors:   The Korean Logistics Research Association, Kim Chang-Bong , Jeong Kyeong-Wook , Yang Hye-Jeong , Oh Yu-Jin
Published: March 2023

Recently, the size of the global cold chain market is growing. Therefore, the cold chain has increased management risks. The purpose of this study is to identify potential supply chain risk factors that could emerge during the operation of the cold chain logistics system for small and medium-sized export businesses. Additionally, we attempted to comprehend how risk management affected the effectiveness of logistics and shipping.
Structured questionnaires were distributed from October 11, 2022, to October 28, 2022, focused on lists of randomly chosen member organizations, including the Korea International Trade Association, the Korea Fisheries Trade Association, the Korea Pharmaceutical Bio Association, the Korea Trade-Investment Promotion Agency, and the Korea Small and Medium Business Association. As for the survey method, about 225 copies were collected by distributing Google questionnaires online, and a total of 202 copies were used for empirical analysis, excluding 23 insincere copies. For empirical analysis, the Smart PLS statistical package was used to evaluate external measurement models, internal structural model evaluation, and structural equation modeling, focusing on conceptual research models.
The results of this study are as follows. Among risk factors, low temperature maintenance risk had a negative (-) effect on cold chain risk management, and transportation environment risk and information technology risk had a significant positive (+) effect on cold chain risk management. And risk management was found to have an effect on responsiveness and flexibility in shipping and logistics. This study supplements the contents of previous studies on the risks that small and medium-sized export companies with limited human and financial resources may encounter in the process of operating a cold chain logistics system and examines the causal relationship that related risk management has on shipping logistics efficiency.
Radiologic features of hepatocellular carcinoma related to prognosis
Authors: Hwang Shin Hye , Rhee Hyungjin
Published: March 2023

The cross-sectional imaging findings play a crucial role in the diagnosis of hepatocellular carcinoma (HCC). Recent studies have shown that imaging findings of HCC are not only relevant for the diagnosis of HCC, but also for identifying genetic and pathologic characteristics and determining prognosis. Imaging findings such as rim arterial phase hyperenhancement, arterial phase peritumoral hyperenhancement, hepatobiliary phase peritumoral hypointensity, non-smooth tumor margin, low apparent diffusion coefficient, and the LR-M category of the Liver Imaging-Reporting and Data System have been reported to be associated with poor prognosis. In contrast, imaging findings such as enhancing capsule appearance, hepatobiliary phase hyperintensity, and fat in mass have been reported to be associated with a favorable prognosis. Most of these imaging findings were examined in retrospective, single-center studies that were not adequately validated. However, the imaging findings can be applied for deciding the treatment strategy for HCC, if their significance can be confirmed by a large multicenter study. In this literature, we would like to review imaging findings related to the prognosis of HCC as well as their associated clinicopathological characteristics.
La poligamia y la pluriparentalidad en los distintos ordenamientos jurídicos
Authors: Jaramillo Manzano Juan David
Published: March 2023

Si bien desde la constitución política de 1991 Colombia a realizado grandes a avances en materia de protección de derechos, hay un aspecto en el derecho de familia que ha sido desatendido: la familia plural. Esta figura, compuesta por las esferas de la poligamia y la pluriparentalidad, ya ha visto importantes avances en otros ordenamientos jurídicos, como lo son Brasil, Canadá y Estados Unidos; países que, ya sea por medio de una ley o mediante un precedente judicial, han logrado presentar una discusión que, con argumentos como la socioafectividad, o el mayor interés del menor, se han visto resueltas en la aceptación de estas figuras en sus ordenamientos. Es momento de que, como lo hicieron estos países, Colombia empiece una discusión argumentada sobre el tema.
La Orientación sexual y la empatía en adultos heterosexuales y homosexuales
Authors: Rancruel Reyes Santiago , Garcés Cifuentes Juliana , Marmolejo Ferro Gabriela , González Gallego Juliana
Published: March 2023

La presente investigación analizó la relación entre la orientación sexual y los niveles de empatía en adultos homosexuales y heterosexuales hacia situaciones de discriminación por orientación sexual y por discapacidad. Se realizó un cuestionario relacionado con las dimensiones del Índice de Reactividad Interpersonal (IRI) para medir la empatía situacional (cognitiva y afectiva) de los participantes, y una tarea de identificación con la historia de una víctima para evaluar la compenetración emocional. Las hipótesis fueron que los participantes homosexuales tendrían mayores niveles de empatía que los participantes heterosexuales hacia las víctimas, independientemente de la discriminación; y que los participantes homosexuales serían más empáticos cuando la persona es discriminada por orientación sexual. Los resultados apoyaron las hipótesis: los participantes homosexuales mostraron mayores niveles de empatía situacional en comparación con los participantes heterosexuales para ambas situaciones de discriminación; y los participantes homosexuales presentaron mayores niveles de empatía situacional para situaciones de discriminación por orientación sexual que por discapacidad. Estos hallazgos sugieren una fuerte relación entre la variable de “orientación sexual” y el nivel de empatía situacional. La investigación podría ampliar el campo teórico de la empatía, la orientación sexual, su relación con la discriminación y su influencia en el reconocimiento de la diversidad sexual.
The Pattern of Intraocular Pressure After Phacoemulsification Surgery In Senile Cataract
Authors: Meida Nur Shani , Ikliluddin Ahmad , Setyandriana Yunani , Rahmawati Vania
Published: March 2023

Phacoemulsification is a surgical procedure for cataracts, which can increase intraocular pressure (IOP) and cause blindness due to glaucoma. It was known that the pattern of IOP changes after phacoemulsification surgery in senile cataracts. This study was an observational analytic study without a control group design. The study population was male and female senile cataract patients over 40 years of age who underwent phacoemulsification surgery at Kebumen Eye Centre Clinic in 2020. Intraocular pressure measurements using a Noncontact Tonometry by a nurse were carried out before surgery (D-0) and postoperatively on day 2 (D-2), day 9 (D-9), day 16 (D-16), and day- 23 (D-23). The data were analyzed using the Friedman test followed by the Post Hoc LSD test. The Friedman test results showed significant differences (p 0.05) in the IOP measurement at D-0, D-2, D-9, D-16, and D-23. Wilcoxon post hoc test showed IOP measurements on D-2  increased and then decreased normally. There was a change in the IOP pattern after phacoemulsification surgery, in which the IOP increased significantly on D-2 and then decreased normally.
Antimicrobial Activity of Pecut Kuda Leaf Extract (Stachytarpheta jamaicensis (L. Vahl) against Mycobacterium smegmatis
Authors: Ramadhani Putri Nadia , Kurniati Ika Dyah , Rakhmawatie Maya Dian
Published: March 2023

Mycobacterium smegmatis infrequently causes infection, but it is easy to be pathogenic in immunosuppressed patients. Many reported that M. smegmatis resistance to several antibiotics became an impetus for searching for new antimicrobials. Therefore, this study aims to prove the effect of Pecut Kuda leaf extract (Stachytarpheta jamaicensis (L.) Vahl) on the growth of M. smegmatis mc2 155. This research is an experimental study with a post-test control group design. The susceptibility test was carried out using the two-fold microdilution method and resazurin staining. The concentration of Pecut Kuda leaf ethanol extract was prepared in the concentration range of 10000.0 – 625.0 µg/ml.  Phytochemical analysis of the content of saponins, tannins, flavonoids, and alkaloids was also carried out on Pecut Kuda leaf ethanol extract. Pecut Kuda leaf ethanol extract can inhibit the growth of M. smegmatis with a minimum inhibitory concentration (MIC) of 5000 µg/ml (very weak activity) because, at the highest concentration of 10000 µg/ml, M. smegmatis still cannot be killed. Furthermore, Pecut Kuda leaf ethanol extract contains saponins, tannins, flavonoids, and alkaloids which are known to have antibacterial activity. However, further evaluation is needed to maximize the antibacterial activity of Pecut Kuda leaf extract, for example, by fractionating the extract.
Epithelial Mucosal Changes and An Inflammation Process of the Cavum Nasi Due to Inhaled Sawdust
Authors: Yusran Yusmawati , Lubis Humairah Medina Liza
Published: March 2023

Woodworkers are particularly susceptible to inhalation of sawdust exposure. Exposure to sawdust for a long time causes various health problems and causes the damage of the epithelium to a barrier. This study aims to identify whether inhaled sawdust can cause changes in the nasal mucosa and the occurrence of an inflammatory process. This study was a cross-sectional analytical study. Data were collected from July 2021 to January 2022 from the nasal cavity swab of 35 woodworkers who had worked for 1 to 5 years. The assessment was carried out by cytological examination to identify epithelial changes in the form of mild and moderate dysplasia, while the inflammation was found in the form of acute and chronic inflammation. Twenty-six (74.3%) samples were normal, 7 (20%) samples had mild dysplasia, and 2 (5.7%) samples had moderate dysplasia. Whereas 20 (57.1%) were found to have no inflammation, 8 (22.9%) were with acute inflammation, and 7 (20.0%) were found to have chronic inflammation). Fisher’s exact test showed a relationship between the inflammatory process and epithelial changes (p 0.020). In conclusion, sawdust inhaled showed changes in the epithelial mucosa and inflammatory processes of the nasal cavity.
The Factors Related to Cadres’ Competency in Integrated Health Service Post during Pandemic
Authors: Rahman Ferry Fadzlul , Darsono Susilo Nur Aji Cokro , Sunarti Sri
Published: March 2023

The competence of Posyandu (Integrated Service Post) cadres played a crucial role in response to the pandemic. They were responsible for raising awareness about COVID-19 and implementing preventive measures. The impact of their competence cannot be overstated and highlights the importance of investing in health worker training. This study aims to determine the factors related to the competence of Integrated Health Service Post cadres during the pandemic in the Samarinda Primary Healthcare working area. Observational research was employed with stratified random sampling, and primary data was collected from five Primary Healthcare in Samarinda. This study employed three steps to examine the effect of competency cadres: univariate analysis, bivariate analysis using the Spearman Rank test, and multivariate analysis with Multiple Linear Regression. The bivariate analysis results showed that supervision had a very strong correlation with the cadres’ competency, and social environment had a strong correlation with the cadres’ competency. At the same time, the organization had a moderate correlation with cadres’ competency. The multivariate test results showed that the social environment contributed 0.165 times to the competence of cadres, organizational support contributed 0.211 times in cadre competence, and supervision support contributed 0.652 times to cadre competence. It provides them with the necessary resources, training, and recognition for their work.
Comparative evaluation of the clinical performance of supraglottic airways- Supreme laryngeal mask airway, I gel and baska mask
Authors: Phalgune Deepak , Cherian Lilly , Thatte Janhavi , Mahadik Shripad
Published: March 2023

There are no studies comparing Supreme laryngeal mask airway (LMA), I gel and Baska mask in Indian population. A comparison of the clinical performance of Supreme LMA, I gel and Baska mask was undertaken in this randomized controlled study.

The present research was undertaken in 75 patients aged 18 to 60 years who underwent elective surgery for less than 3-hour duration under general anaesthesia. The patients were randomly divided into three groups; Supreme LMA, I gel, and Baska mask. The oropharyngeal leak pressure (OLP) after 30 minutes to loss of spontaneous respiration was the primary objective, whereas the secondary objectives were attempts required for insertion of LMA, ease of gastric tube insertion, time required for gastric tube insertion and post-operative morbidity.

The mean OLP of Baska mask group was (28.2 cm HO) as compared to Supreme LMA (25.3 cm HO) and I-gel (24.1 cm HO) groups (p-value = 0.0001). The mean gastric tube insertion time of Baska mask group was (20.7 s) as compared to Supreme LMA (6.7 s) and I-gel (9.6 s) groups (p-value = 0.0001). The three groups were comparable with regards to the number of attempts required, ease of gastric tube insertion and post-operative morbidity.

A higher OLP was observed in Baska mass group as compared to Supreme LMA and I-gel. The three devices were similar in terms of attempts required for insertion, ease of gastric tube insertion and post-operative morbidity.
Anaesthetic challenges faced in a child with Morquio syndrome- An orphan disease
Authors: Ahmed Tasneem Fathima , Krishnan S Navaneetha , Ramakrishnan Lakshmi
Published: March 2023

: Morquio syndrome is a progressive lysosomal storage disorder leading to accumulation of glycosaminoglycans in the soft tissue, cartilage, and bone causing skeletal dysplasia.

: We present a four-year-old child diagnosed with right side inguinal hernia posted for herniotomy. He had a large head with short neck and kyphoscoliosis. Pre-operative MRI whole spine shows a hypoplastic dens causing canal stenosis, indenting the cord at C1 level. General Anesthesia was planned. With a video laryngoscope on standy by, patient was induced after stabilizing the neck with a custom neck collar and the airway was secured with a Proseal Laryngeal Mask Airway.

: The airway management can be challenging because of accumulation of mucopolysaccharides in the soft tissue of upper airway and limited mouth opening due to involvement of temporo mandibular joints.

A thorough pre-operative evaluation of airway must be done and a well planned anaesthetic technique must be executed.
Recent insights into the role of antifibrotic drugs in the management of idiopathic pulmonary fibrosis (IPF)
Authors: Chakraverty Raja , Bondyopadhyay Jyotirmoy
Published: March 2023

Idiopathic aspiratory fibrosis (IPF) is the most well-known sort of idiopathic interstitial pneumonia (IIP). IIPs are precipitously shappening (idiopathic) diffuse parenchymal lung illnesses. IPF is characterized as a precipitouly happening (idiopathic) explicit type of persistent fibrosing interstitial pneumonia restricted to the lung and related with an example of Usual Interstitial Pneumonia (UIP) on imaging or histology. Pleasant rules for the analysis of Interstitial Lung Disease (ILD), preceding thought for against fibrotic treatment, specify that the conclusion of ILD has been made by a multidisciplinary group (MDT).
Fixed dose combinations in India- what a way to go!
Authors: Chaudhry Sunil
Published: March 2023

Fixed dose combinations (FDCs) are generally considered desirable options in chronic diseases such as tuberculosis, cardiovascular diseases & diabetes, tropical diseases such as malaria & in HIV and in Cancer. FDCs are useful in chronic conditions especially when multiple disorders often co-exist The advantages of the FDC are basically patients compliance, simple dosage schedule, better efficacy, cheaper shipment & packaging activities. The drawbacks of FDCs are (a) Pharmacodynamic mismatch between the two ingredients, one drug having additive/antagonistic effect leading to reduced efficacy or enhanced side effects, (b) Pharmacokinetic disparity having peak efficacy at different time zone, (c) Chemical non compatibility leading to decreased shelf life, (d) Drug interactions due to common metabolizing pathways, and (e) limitations of dose titration of individual ingredients. As per Rule 122 E of Drugs and Cosmetics Act 1940, the FDCs are considered as New Drugs where the Central Drugs Standard Control Organization (CDSCO), ensures proper clinical data is submitted for the approval into the market. Appendix VI of Schedule Y (Drugs & Cosmetics Rules 1945) mentions the requirements for marketing approval of various types of FDCs.
Commentary on cardiovascular safety of DPP4Is: Focus on Alogliptin
Authors: Trailokya Abhijit Anil , Zargar Abdul Hamid , Tiwaskar Mangesh , Kale Santosh , Shirsat Amar
Published: March 2023

DPP-4 inhibitors are present in the market for almost more than a decade. In Management of T2DM, DPP-4 inhibitors are established therapy option. The precise guidance for the pre- and post-approval and also CV safety of the newer antidiabetic agents was released by the USFDA in 2008. A neutral effect of Pooled safety analyses, as well as retrospective meta-analyses of clinical trials, have consistently demonstrated that DPP-4 inhibitors are not associated with any increase in cardiovascular adverse events, and have even pointed towards a risk reduction. The combination therapy of Alogliptin with other agents like metformin and pioglitazone have been shown to provide better and superior efficacy as compared to individual monotherapy. The hypoglycemic risk is less with Alogliptin. Alogliptin has been shown to be associated with less risk of hepatotoxicity, weight gain, and acute pancreatitis. Alogliptin does not worsen outcomes in patients with a history of heart failure (HF), neither does it increase rate of new hospitalization for heart failure (HF), as per the data from EXAMINE trial.
Nuevas referencias biográficas y documentales sobre el maestro de capilla José Joaquín Zameza y Elejalde (*Ibarra, 22-03-1731; †Antequera, 1-08-1796)
Authors: Delafuente Charlfolé José Luis
Published: March 2023

El presente estudio aporta la documentación que corrige el año de nacimiento, unifica la trayectoria y define el auténtico nombre y naturaleza del compositor José Zameza y Elejalde a partir de los referentes contenidos en un acta de oposición a maestro de capilla en la Catedral de Cuenca el año 1768.
Nadużycie (prawa do) anonimatu przez dziennikarzy. Wymiar praktyczno-prawny
Authors: Goniak Łukasz Paweł
Published: March 2023

Celem niniejszego artykułu jest analiza sposobu korzystania przez dziennikarzy z prawa do anonimatu. Autora interesuje nie tylko samo pierwotnie zakładane przeznaczenie tego prawa (perspektywa teoretyczna), ale przede wszystkim porównanie, na ile obecne zachowanie dziennikarzy w tym zakresie jest zgodne z założeniem, jakiemu prawo to prymarnie miało służyć. Podstawą udzielenia odpowiedzi na zadane pytanie są wyniki badań przeprowadzonych przez autora – przede wszystkim jakościowych (obserwacja uczestnicząca i wywiady pogłębione), ale również ilościowych (sondaż). W tekście odniesiono się także do poszczególnych przypadków skorzystania przez dziennikarzy z prawa do anonimatu (case-study). Analiza danych wskazuje, że sposób, w jaki dziennikarze decydują się używać współcześnie prawa do anonimatu, może budzić wątpliwości choćby natury etycznej. Dlatego naturalne staje się pytanie, czy prawo do anonimatu w ogóle obejmuje swoim zakresem tego typu działania.
El interés del desinterés en la epidemiología de servicios y sistemas de salud
Authors: Spinelli Hugo
Published: March 2023

Este trabajo se propone problematizar, discutir y publicizar la autoridad cultural de la medicina científica, desde una dimensión política, y la implementación de la epidemiología de los servicios y sistemas de salud, desde una dimensión técnica. A partir de los conceptos de interés del desinterés, de Pierre Bourdieu, y de autoridad cultural de los problemas públicos de Joseph Gusfield se analiza ¿por qué la información epidemiológica es tan poco utilizada para la evaluación y monitoreo de las prácticas clínicas, poblacionales, institucionales y territoriales?, ¿por qué domina una cultura de toma de decisiones sin información epidemiológica? Desde este marco conceptual, se aborda un cuerpo documental que permite recuperar la débil cientificidad que sustentaron o sustentan algunas prácticas del campo de la salud en diferentes momentos históricos, organizado en tres ejes temáticos: la práctica profesional asistencial, los medicamentos y las tecnologías biomédicas.
Generalized fractional kinetic equations involving incomplete Aleph - function
Authors: Arya Jagdish Chandra
Published: March 2023

Due to the great importance of the fractional kinetic equations, many authors discussed the generalizations of fractional kinetic equation involving various special functions. The purpose of this paper is to obtain the new generalization of fractional kinetic equation pertaining to the incomplete Aleph-function. The solution of the fractional kinetic equations obtained here by using Laplace and Sumudu transforms method. The Riemann-Liouville fractional integral operator is used to obtain the required results. The Solution of the generalized fractional kinetic equation are obtained by using the definition of incomplete Aleph function. The result discussed here can be used for the study of the chemical composition change in stars like the Sun. The solution rendered here are in compact forms suitable for numerical computation. Some special cases involving incomplete I –functions and incomplete H –functions are also considered.
Determinants of nutritional recovery status and survival time among children from 0 to 14 years old with acute malnutrition admitted to a therapeutic feeding center in Oromia, Southern Ethiopia: A retrospective cohort study
Authors: Sanchez-Lopez Maria Inmaculada , Giner-Oliver Maria Del Mar , Lluesma-Vidal Marta , Garcia-Garces Laura , Trull-Ahuir Carmen , Ruiz-Zaldibar Cayetana
Published: March 2023

Some studies have been conducted in Ethiopia to analyze the predictive factors associated with recovery or mortality in children with acute malnutrition, but no recent studies carried out in Oromia have analyze nutritional recovery status in this children. we studied the factors affecting nutritional recovery for survival in acutely malnourished children Southern Ethiopia. cohort study that included the children admitted to the (blinded for review) hospital (Oromia, Ethiopia) for acute malnutrition from January 2015 to December 2016 (n = 440). Kaplan–Meier tests and log-rank tests were used to describe the survival. Chi-squared tests and Spearman and Mann–Whitney U correlation tests were also employed. The mean survival time was shorter in children with severe versus moderate malnutrition at admission (49 days vs. 101 days; log-rank p = 0.042). The survival time was shorter in children with severe acute malnutrition at the time of admission. Survival time of children with moderate acute malnutrition was shorter in children who came from rural areas compared to urban areas. Severe acute malnutrition was associated with hospital stays, death rates, or transfer to another hospital. Practical implications: the results of this study may improve the care of children with malnutrition.
The restaurant business model as a multidimensional construct supporting the management of the food service industry enterprise
Authors: Dereń Anna
Published: March 2023

Purpose of the study: This article discusses the concept of a business model. Various concepts are presented to define this research object.

Methodology: The survey was conducted on a group of restaurants from Krakow. The study allowed us to identify three business models.

Main findings: It has been shown that there is no unanimity among researchers, not only as to what a business model is (a plan, a tool, a description of a system) but also as to its components. By characterizing the universal types of business models, with particular emphasis on the nature of restaurant business models, it was shown that the model should be best adapted to the specifications of the sector and the objectives of the company, and also the components may differ concerning the other sectors' business models and concerning the other sectors' business models. The business model is directly related to management strategy, so it should be a plan providing the best possible operation of the company that allows it to be competitive in the field.

Application of the study: A realistic depiction of the restaurant business model diversity.

Originality/Novelty of the study: The work combines theoretical and practical approaches to the topic of business models with a particular focus on the gastronomy industry.
Middle-age brand identity crisis
Authors: Cruz Costa Alves Antonio Pedro , Rodrigues Fabiano , Strehlau Vivian Iara
Published: March 2023

Objective: This paper aimed to provide a systematic review of brand identity and understand how literature streams impact the current brand identity frameworks.
Method: There are few systematic reviews about this salient topic, and the existing ones have not analyzed how the research in brand identity has evolved in the last 30 years, what have been the leading research streams and gaps, and which future avenues of study could be pursued. To fill this gap, this paper analyzed 67 articles published in 24 leading academic journals (Academic Journal Guide grades 3, 4, and 4*) between 1990 and 2021.
Main Results: Five key research streams were identified: brand identity frameworks; consumer behavior; corporate branding; visual brand identity; co-creation. Despite the impressive progress made over the last 30 years, our review points out what we defined as a “middle-age brand identity crisis”, since there is still no convergence among scholars about what brand identity is and what would be its main components. Also, the current research streams uncover concepts and ideas that were not previously included in brand identity frameworks.
Relevance / Originality: This study performed a comprehensive systematic analysis of the brand identity literature, highlighting essential recent research not considered by the current brand identity frameworks and connecting it to branding constructs. We also identified that there is still a lack of consensus regarding the brand identity components and dimensions.
Theoretical / Methodological Contributions: This paper contributes to the literature by presenting a new framework to shed light on the interactions of brand identity with other branding constructs, proposing that brand identity has a core (brand essence) and extended identity (composed of personality, relationship, symbology, and cultural expressions). A new brand identity taxonomy is also proposed, with complexity and tangibility as its dimensions.
Translating the Gāyatrī-Mantra
Authors: Haas Dominik A.
Published: March 2023

No single standard translation of the mantra known as Sāvitrī, Gāyatrī, or Gāyatrī-Mantra (Ṛgveda III 62.10) has ever become widely accepted. Many authors seem to have felt that a famous mantra such as this one must have, or allow for, several interpretations and translations – a position that is not without justification, especially when it comes to mantras. Yet, translators of the Gāyatrī-Mantra have rarely taken into consideration that language changes over time, and that this has an impact on how the mantra is to be translated. The aim of this paper is to remedy this situation. It provides grammatical, morphological, etymological, lexical, and semantic analyses of the textual content of the mantra against the background of the linguistic changes that took place during the transition from early to late Old Indo-Aryan. In other words, this paper explores how the mantra would be understood by users of Vedic and Sanskrit. To this end, each textual component of the Gāyatrī-Mantra is analyzed in dedicated sections. An appendix also provides a collection of more than sixty scholarly translations into European languages.
LAK of Direction
Authors: Motz Benjamin A. , Bergner Yoav , Brooks Christopher A. , Gladden Anna , Gray Geraldine , Lang Charles , Li Warren , Marmolejo-Ramos Fernando , Quick Joshua D.
Published: March 2023

Learning analytics defines itself with a focus on data from learners and learning environments, with corresponding goals of understanding and optimizing student learning.  In this regard, learning analytics research, ideally, should be characterized by studies that make use of data from learners engaged in education systems, should measure student learning, and should make efforts to intervene and improve these learning environments. However, a common concern among members of the learning analytics research community is that these standards are not being met.  In two analysis waves, we review a large and comprehensive sample of research articles from the proceedings of the three most recent Learning Analytics and Knowledge conferences, the premier conference venue for learning analytics research, and from articles published during the same time in the Journal of Learning Analytics (over the years of 2020, 2021, and 2022).  We find that 37.4% of articles do not analyze data from learners in an education system, 71.1% do not include any measure of learning, and 89.0% of articles do not attempt to intervene in the learning environment.  We contrast these findings with the stated definition of learning analytics and infer, like others before us, that scholarship in learning analytics research presently lacks clear direction toward its stated goals.  We invite critical discussion of these findings from the learning analytics community, through open peer commentary.
OECD Ülkelerinde Gelir Eşitsizliği-Gösteriş Tüketimi İlişkisi: Uzun Dönemli Bir Analiz
Authors: Bilik Mustafa , Aydın Üzeyir
Published: March 2023

Bu çalışmada, OECD ülkelerinde gelir dağılımı ve tüketim harcamaları incelenmektedir. Bu çerçevede 34 OECD ülkesini ve 1970-2021 dönemini kapsayan veri seti kullanılmıştır. Çalışmada hem içsellik problemini gidermek hem de uzun dönemde dinamik süreci daha iyi açıklayabilmek amacıyla “Dinamik panel veri” tekniği uygulanmıştır. Buna ek olarak, söz konusu ilişki üç farklı gelir dağılımı göstergesi üzerinden incelenmiştir. Bu sayede, nispi gelir hipotezinin uzantıları olarak ele alınan, Frank (2014) ve Christensen ve Morgan (2005) hipotezleri test edilmiş, ayrıca uygulama sonuçlarının dirençli olup olmadığını sorgulanmıştır. Elde edilen bulgular gelir eşitsizliğindeki artışın toplam harcamaları artırdığını göstermektedir. Bu sonuç “Gösteriş tüketimi” olgusunu doğrulamakta ve dolayısıyla Duesenberry (1949)’nin hipotezini destekleyen katsayı ile örtüşmektedir. Buna göre, gelir eşitsizliğindeki artış, gösteriş tüketimi üzerinden toplam harcamaları artırmaktadır.
Anahtar Kelimeler: Tüketim Harcamaları, Gelir dağılımı, Panel veri Analizi.
JEL Sınıflandırması: D12, D31, C23
Molecular genetic basis of epidermolysis bullosa
Authors: Kotalevskaya Yu. Yu. , Stepanov V. A.
Published: March 2023

Epidermolysis bullosa (EB) is an inherited disorder of skin fragility, caused by mutations in a large number of genes associated with skin integrity and dermal-epidermal adhesion. Skin fragility is manifested by a decrease in resistance to external mechanical influences, the clinical signs of which are the formation of blisters, erosions and wounds on the skin and mucous membranes. EB is a multisystemic disease and characterized by a wide phenotypic spectrum with extracutaneous complications in severe types, besides the skin and mucous membranes, with high mortality. More than 30 clinical subtypes have been identified, which are grouped into four main types: simplex EB, junctional EB, dystrophic EB and Kindler syndrome. To date, pathogenic variants in 16 different genes are associated with EB and encode proteins that are part of the skin anchoring structures or are signaling proteins. Genetic mutations cause dysfunction of cellular structures, differentiation, proliferation and apoptosis of cells, leading to mechanical instability of the skin. The formation of reduced proteins or decrease in their level leads mainly to functional disorders, forming mild or intermediate severe phenotypes. Absent protein expression is a result of null genetic variants and leads to structural abnormalities, causing a severe clinical phenotype. For most of the genes involved in the pathogenesis of EB, certain relationships have been established between the type and position of genetic variant and the severity of the clinical manifestations of the disease. Establishing an accurate diagnosis depends on the correlation of clinical, genealogical and immunohistological data in combination with molecular genetic testing. In general, the study of clinical, genetic and ultrastructural changes in EB has significantly expanded the understanding of the natural history of the disease and supplemented the data on genotype-phenotype correlations, promotes the search and study of epigenetic and non-genetic disease modifier factors, and also allows developing approaches to radical treatment of the disease. New advances of sequencing technologies have made it possible to describe new phenotypes and study their genetic and molecular mechanisms. This article describes the pathogenetic aspects and genes that cause main and rare syndromic subtypes of EB.