bluuebunny/crossref_metadata_2025 huggingface dataset:
The "enemies within": regions of the genome that are inherently difficult to replicate
Authors: Bhowmick Rahul , Hickson Ian D
Published: May 2017

An unusual feature of many eukaryotic genomes is the presence of regions that appear intrinsically difficult to copy during the process of DNA replication. Curiously, the location of these difficult-to-replicate regions is often conserved between species, implying a valuable role in some aspect of genome organization or maintenance. The most prominent class of these regions in mammalian cells is defined as chromosome fragile sites, which acquired their name because of a propensity to form visible gaps/breaks on otherwise-condensed chromosomes in mitosis. This fragility is particularly apparent following perturbation of DNA replication—a phenomenon often referred to as “replication stress”. Here, we review recent data on the molecular basis for chromosome fragility and the role of fragile sites in the etiology of cancer. In particular, we highlight how studies on fragile sites have provided unexpected insights into how the DNA repair machinery assists in the completion of DNA replication.
Wnt target genes and where to find them
Authors: Ramakrishnan Aravinda-Bharathi , Cadigan Ken M.
Published: May 2017

Wnt/β-catenin signaling is highly conserved throughout metazoans, is required for numerous essential events in development, and serves as a stem cell niche signal in many contexts. Misregulation of the pathway is linked to several human pathologies, most notably cancer. Wnt stimulation results in stabilization and nuclear import of β-catenin, which then acts as a transcriptional co-activator. Transcription factors of the T-cell family (TCF) are the best-characterized nuclear binding partners of β-catenin and mediators of Wnt gene regulation. This review provides an update on what is known about the transcriptional activation of Wnt target genes, highlighting recent work that modifies the conventional model. Wnt/β-catenin signaling regulates genes in a highly context-dependent manner, and the role of other signaling pathways and TCF co-factors in this process will be discussed. Understanding Wnt gene regulation has served to elucidate many biological roles of the pathway, and we will use examples from stem cell biology, metabolism, and evolution to illustrate some of the rich Wnt biology that has been uncovered.
Leishmaniasis: a review
Authors: Torres-Guerrero Edoardo , Quintanilla-Cedillo Marco Romano , Ruiz-Esmenjaud Julieta , Arenas Roberto
Published: May 2017

Leishmaniasis is caused by an intracellular parasite transmitted to humans by the bite of a sand fly. It is endemic in Asia, Africa, the Americas, and the Mediterranean region. Worldwide, 1.5 to 2 million new cases occur each year, 350 million are at risk of acquiring the disease, and leishmaniasis causes 70,000 deaths per year. Clinical features depend on the species ofLeishmaniainvolved and the immune response of the host. Manifestations range from the localized cutaneous to the visceral form with potentially fatal outcomes. Many drugs are used in its treatment, but the only effective treatment is achieved with current pentavalent antimonials.
Recent advances in understanding contextual TGFβ signaling
Authors: Ayyaz Arshad , Attisano Liliana , Wrana Jeffrey L
Published: May 2017

The appearance of the first animal species on earth coincides with the emergence of transforming growth factor β (TGFβ) pathways. The evolution of these animals into more complex organisms coincides with a progressively increased TGFβ repertoire through gene duplications and divergence, making secreted TGFβ molecules the largest family of morphogenetic proteins in humans. It is therefore not surprising that TGFβ pathways govern numerous aspects of human biology from early embryonic development to regeneration, hematopoiesis, neurogenesis, and immunity. Such heavy reliance on these pathways is reflected in the susceptibility to minor perturbations in pathway components that can lead to dysregulated signaling and a diverse range of human pathologies such as cancer, fibrosis, and developmental disorders. Attempts to comprehensively resolve these signaling cascades are complicated by the long-recognized paradoxical role the pathway plays in cell biology. Recently, several groups have probed examples of the disparate aspects of TGFβ biology in a variety of animal models and uncovered novel context-dependent regulatory mechanisms. Here, we briefly review recent advancements and discuss their overall impact in directing future TGFβ research.
MinION Analysis and Reference Consortium: Phase 2 data release and analysis of R9.0 chemistry
Authors: Jain Miten , Tyson John R. , Loose Matthew , Ip Camilla L.C. , Eccles David A. , O'Grady Justin , Malla Sunir , Leggett Richard M. , Wallerman Ola , Jansen Hans J. , Zalunin Vadim , Birney Ewan , Brown Bonnie L. , Snutch Terrance P. , Olsen Hugh E. ,   MinION Analysis and Reference Consortium
Published: May 2017

Background: Long-read sequencing is rapidly evolving and reshaping the suite of opportunities for genomic analysis. For the MinION in particular, as both the platform and chemistry develop, the user community requires reference data to set performance expectations and maximally exploit third-generation sequencing. We performed an analysis of MinION data derived from whole genome sequencing of Escherichia coli K-12 using the R9.0 chemistry, comparing the results with the older R7.3 chemistry.

Methods: We computed the error-rate estimates for insertions, deletions, and mismatches in MinION reads.

Results: Run-time characteristics of the flow cell and run scripts for R9.0 were similar to those observed for R7.3 chemistry, but with an 8-fold increase in bases per second (from 30 bps in R7.3 and SQK-MAP005 library preparation, to 250 bps in R9.0) processed by individual nanopores, and less drop-off in yield over time. The 2-dimensional (“2D”) N50 read length was unchanged from the prior chemistry. Using the proportion of alignable reads as a measure of base-call accuracy, 99.9% of “pass” template reads from 1-dimensional (“1D”)  experiments were mappable and ~97% from 2D experiments. The median identity of reads was ~89% for 1D and ~94% for 2D experiments. The total error rate (miscall + insertion + deletion ) decreased for 2D “pass” reads from 9.1% in R7.3 to 7.5% in R9.0 and for template “pass” reads from 26.7% in R7.3 to 14.5% in R9.0.

Conclusions: These Phase 2 MinION experiments serve as a baseline by providing estimates for read quality, throughput, and mappability. The datasets further enable the development of bioinformatic tools tailored to the new R9.0 chemistry and the design of novel biological applications for this technology.

Abbreviations: K: thousand, Kb: kilobase (one thousand base pairs), M: million, Mb: megabase (one million base pairs), Gb: gigabase (one billion base pairs).
The ICR96 exon CNV validation series: a resource for orthogonal assessment of exon CNV calling in NGS data
Authors: Mahamdallie Shazia , Ruark Elise , Yost Shawn , Ramsay Emma , Uddin Imran , Wylie Harriett , Elliott Anna , Strydom Ann , Renwick Anthony , Seal Sheila , Rahman Nazneen
Published: May 2017

Detection of deletions and duplications of whole exons (exon CNVs) is a key requirement of genetic testing. Accurate detection of this variant type has proved very challenging in targeted next-generation sequencing (NGS) data, particularly if only a single exon is involved. Many different NGS exon CNV calling methods have been developed over the last five years. Such methods are usually evaluated using simulated and/or in-house data due to a lack of publicly-available datasets with orthogonally generated results. This hinders tool comparisons, transparency and reproducibility. To provide a community resource for assessment of exon CNV calling methods in targeted NGS data, we here present the ICR96 exon CNV validation series. The dataset includes high-quality sequencing data from a targeted NGS assay (the TruSight Cancer Panel) together with Multiplex Ligation-dependent Probe Amplification (MLPA) results for 96 independent samples. 66 samples contain at least one validated exon CNV and 30 samples have validated negative results for exon CNVs in 26 genes. The dataset includes 46 exon CNVs in BRCA1, BRCA2, TP53, MLH1, MSH2, MSH6, PMS2, EPCAM or PTEN, giving excellent representation of the cancer predisposition genes most frequently tested in clinical practice. Moreover, the validated exon CNVs include 25 single exon CNVs, the most difficult type of exon CNV to detect. The FASTQ files for the ICR96 exon CNV validation series can be accessed through the European-Genome phenome Archive (EGA) under the accession number EGAS00001002428.
STRENGTHENING OF THE FOUNDATIONS ADMINISTRATIVE AND TRADE BUILDING AT DEEPENING OF THE FLOOR MARKS OF THE CELLAR
Authors: Петухов Аркадий , Petukhov Arkadiy , Полищук Анатолий , Polishchuk Anatoliy , Тарасов Александр , Tarasov Aleksandr
Published: May 2017

Reconstruction of cellar part of the two-storeyed brick building in Tomsk is considered. The main objectives of reconstruction included deepening of a floor of the cellar with 2,5 to 4,5 m with the construction in internal bearing walls of apertures width to 3,5m. Decisions on strengthening of the foundations which provided a reorganization of the rubble tape foundations in concrete with use of injection piles are developed. Thus the mark of a sole of the new foundation is arranged 1,4 m below than a sole of the existing foundation
ABOUT THE MODE INFLUENCE OF APPLYING SHOCK LOADS ON THE INDICATORS OF COMPACTIBILITY OF CLAY LOAM
Authors: Халафов Намик , Khalafov Namik , Габибов Фахраддин , Gabibov Fakhraddin , Амрахов Азад , Amrakhov Azad
Published: May 2017

The issues of improvement of ramming or the projective in the form of a truncated cone from recycled tires. It allows to significantly improve the process of surface seal while eliminating subsidence of soil properties at a thickness of up to 5 meters.
Cultural adaptation of international phrasemes containing natural resources terms in the Russian and English languages.
Authors: Шевченко  , Shevchenko Svetlana
Published: May 2017

The article tries to reveal the national particularity of usage of borrowed phrasemes, to show that despite their international character they function differently in different target languages adapting to culture, traditions, reflecting national psychology. The semantics of the same phraseological calque varies to some extent in various languages. The context of usage, frequency and relevance to the culture may vary significantly. The article describes some phrasemes with supplemental words, semantic extension, cases when collocations undergo further mataphorisation. Among the international phrasemes to be compared are some borrowings from the Bible, classic phrasemes of antique origin, mythologems. The diachronic processes leading to alteration of frequency, coining or losing of some connotations are also studied. The phraseme is considered to be like a living thing which adapts to a cultural environment and reacts to the changes occurring in it. The article contributes to cultural linguistics, helps to find the ways of fruitful intercultural communication.
Monuments on the planning structure ensembles of the Novocherkassk
Authors: Тумасов Александр , Волк Ольга , Volk Olga
Published: May 2017

An important role in shaping the architectural and artistic image of the city have a monumental sculpture. The article analyzes the compositional principles of inclusion monuments in the spatial environment of the city. The analysis of individual fragments of urban space Novocherkassk enriched plastic elements. Based on the analysis the negative patterns of switching sites in the urban environment in recent years.
State of the field in relation to the conservation, absorption and release of energy
Authors: Мизин  , Mizin Sergey
Published: May 2017

Review article includes a fairly complete set of evidence for the transition from the axioms of the theory of relativity, Albert Einstein to a generalized theory of quasi-classical physical field as the "continuum": non-geometrical approach to field theory. Please submit evidence of infidelity and the inapplicability approach Theory of Relativity, and then systematically submitted to substitute results of the theory of physical field. Fully justified timeliness and completeness of such a transition.
Anisotropy of magnetostatic wave group velocities in ferromagnetic waveguides
Authors: Гришин  , Grishin S. , Садовников  , Sadovnikov A. , Романенко  , Romanenko D.
Published: May 2017

The results of theoretical and experimental study of anisotropic propagation of magnetostatic waves (MSW) in ferromagnetic thin-film microsize waveguides are presented. Electrodynamic model of tangentially magnetized ferromagnetic waveguide is developed. On the base of the model, the main features in rotation of group velocity vector of volume MSW (VMSW) by rotating a wave vector and a vector of an external bias magnetic field relative to the axis of symmetry of the waveguide are demonstrated. It is shown, that a decrease in a width of the waveguide to the micron size leads to non-reciprocal propagation of VMSW and to increase of angular divergence between the phase and group velocities of VMSW. The experimental research of T-shaped ferromagnetic microwaveguide demonstrates the difference in power levels of a signal that is branched in the shoulders of T-shaped waveguide when the bias magnetic field is rotated in the waveguide plane.
LABOR POTENTIAL OF CUSTOMS OFFICIALS: CONCEPT, STRUCTURE, EVALUATION
Authors: Хрящев  , Hryaschev V. , Трубицын  , Trubicyn K.
Published: May 2017

In an article devoted to the actual topic for customs of Russia, the problems of the concept, structure and evaluation of the labor potential of customs officials are considered. After considering several approaches leading Russian scientists to the definition of «labor potential», the authors came to the conclusion that at the moment there is no single, universally accepted concept and that its definition and structure will vary depending on the objectives and specificity of work. When analyzing structure of the labor potential of the customs officials, authors identified four components: socio-demographic, professional qualification, socio-personal and psycho-physiological. For each of the components was an attempt to assess labor potential of the customs officials to evaluate its components. The authors have also been modeled algorithm for determining the integrated assessment. The article defines the structure of the labor potential of the personnel of customs authorities. On the basis of the analysis formed the author’s method of estimation

of labor potential, which is a component of a comprehensive system of evaluation of labor potential, simulated algorithm for determining the integrated assessment.
THE EVALUATING OF PERSONAL EFFECTIVENESS OF EMPLOYEES IN THE PERSONNEL STIMULATION SYSTEM OF THE BANK
Authors: Каштанова  , Kashtanova YEkatyerina , Лобачёва  , Lobacheva Anastasia
Published: May 2017

The article presents arguments justifying the role and importance of assessment of efficiency of employees in the General system of stimulation of personnel of the organization. The modern approach to the development of a system of material incentives associated with performance management of staff is described, for example, the large domestic banks. The evaluation criteria of efficiency of employees are reviewed and systemized, the principles of evaluation are grouped, the basic evaluation stages of efficiency in order to improve the system of staff incentives are considered. Examples of defining criteria for determining individual awards are given. Possible to the application rules for the assessment of the personal performance of the employees immediate supervisor and subsequent distribution of bonuses are described. Conclusions about the significance of the assessment of personal performance of employees of large organizations and the opportunities for its subsequent use in the enterprise are made.
EXPERIMENTAL RESEARCH OF A HINGE UNIT OF STEEL SPATIAL GRID FRAMINGS
Authors: Алексеев Сергей , Alekseev Sergey , Царитова Надежда , Tsaritova Nadezhda , Бузало Нина , Buzalo Nina , Петров Игорь , Petrov Igor
Published: May 2017

The authors carried out a research of the stress - strain state of the hinge unit of light spatial grid framings of regular structure. The solid model of the hinge unit was created previously and numerical simulation was performed. Calculation identified, that the weak point of the hinge unit is connecting disk. Plastic deformation can arise in the disk during loading. The experimental research was required for verification of results of a pilot study. The test of disk was executed with application of a specially designed installation on universal tensile testing machine in the laboratory of the University. Mechanical characteristics of steel, from which the disk was made, were identified by a certified laboratory destructive control methods in accordance with the GOST. The experimental results are compared with the simulation results. The authors give recommendations for optimizing the design of the hinge unit.
INFLUENCE OF DENSITY AND LENGTH OF CUTTING OF BASALT FIBER ON PHYSICAL AND MECHANICAL INDICATORS OF COMPOSITE DISPERSION-REINFORCED ASPHALT-CONCRETE MIXTURE
Authors: Андронов  , Andronov Sergey , Задирака  , Zadiraka Aleksey
Published: May 2017

Experiments on the introduction of basalt fiber with various density and length of cutting into the composition of the dispersed-reinforced asphalt mixture were carried out, laboratory tests of asphalt concrete samples were carried out, the optimal density and length of cutting basalt fiber for introduction into asphalt concrete mixtures

In transport construction, asphalt concrete is widely used, which is prone to cracking, peeling, chipping, formation of stakes, waves and depressions. The way to increase the resistance of asphalt concrete to external loads is the introduction of fibers and threads into its composition. Introduction to the asphalt-concrete mixture of small (discrete) elements allows to achieve their uniform distribution (dispersion) in the mixture, and to obtain a "composite" material with higher physical and mechanical properties in the finished structural element
Analysis of socio-economic indicators of the far Eastern Federal district of the Russian Federation
Authors: Пономарев  , Ponomarev Maksim , Феоктистов  , Feoktistov Stanislav , Кузнецов  , Kuznecov Zhan
Published: May 2017

The article analyzes the main socio-economic indicators of development of the far Eastern Federal of the Russian Federation and its regions for the period 2000-2015, discusses the problems and prospects of socio-economic development of the far East.
THERMAL RADIATION INTENSITY WHEN USING COMPOSITIONS ON THE SURFACE OF THE PROTECTED CONSTRUCTIONS
Authors: Копытков Владимир , Kopytkov Vladimir , Шныпарков Александр , Shnyparkov Alexander , Старовойтов Павел , Starovoytov Pavel
Published: May 2017

Fire gaps between buildings and household out-buildings on neighboring private plots are regulated in accordance with the technical normative acts (TNA) [1] and can make from 6 to 15 m depending on build-ing levels of resistance to fire. Fire gaps don't often follow these standards because of a number of factors. One of the security techniques of inflammable struc-tures is a gel application on the construction surface which is under thermal radiation because of the near vicinity of the radiation source.

By means of a mathematical apparatus it is shown that using a layer of gel liquid 1 cm thick on a surface of inflammable structures and at direct impact of the thermal flow with 10 kilowatt/m2 density on a wood sample, sample ignition happens in 280-290 seconds after the beginning of influence. In the presence of a 0,5 cm layer of gel liquid ignition occurs in 140-150 seconds after the beginning of influence of the thermal radiation.

Thus, the temperature value in a layer boundary with wood depends on the thickness of composition layer. When using a composition layer on the protected constructions made of wood we may avoid any spreading of the fire in nearby structures that will lead to minimization of material losses and considerable decrease of human casualties.
EVALUATION OF MINERAL RESOURCES POTENTIAL OF THE BRYANSK REGION BY OF GEOLOGICAL AND ECONOMIC MONITORING METHOD
Authors: Дадыкин Валерий , Dadykin Valeriy
Published: May 2017

In the article the application method of geological and economic monitoring for the problem solution of mineral and mineral resources potential evaluation of the territory is described by means of the cost method taking into account the expediency and perspectives of investing into additional exploration and shifting of field reserves to the industrial A+B+C1 categories and transferring forecast resources under P1+P2+P3 cate-gories into geological reserves of C2 category regarding nonmetallic minerals. Having executed the mineral resources potential evaluation of the Bryansk region by means of geologi-cal and economic monitoring method, it should be noted that the Bryansk region takes one of the leading positions among constituent entities of Central Federal District of the Russian Federation by the level of min- eral resource potential. Construction materials take the largest share in nonmetallic mineral resources base; the share of the peat fields of the open acreage is high. Mineral-raw material complex of the region are the most developed in the north-east where the main enterprises of the re-gion mineral-raw material complex are concentrated. A number of exploited and reserve nonmetallic mineral fields allow organizing quite a large and highly effec-tive production of qualitative construction materials in the area.
"GREEN" ECONOMY IN THE CONTEXT OF SOCIO-TECHNOGENIC DEVELOPMENT OF THE WORLD
Authors: Дергачева Елена , Dergacheva Elena
Published: May 2017

Stages of model formation and "green" economy concept in the context of socio-technogenic develop-ment of the world are considered. It is revealed that in the second half of the XX century the interconnected changes in economy and nature generated the interest in formation in the world of environmental economics, searching ways of steady co-evolutional social natural development. It has predetermined the lines of interna-tional cooperation within the UN International Confe-rence on environmental and development matters (1972, 1992, 2002, 2012, 2015, etc.). The conferences served to establish the interrelation of social, economic and ecological factors, to emphasize the importance of interaction of the country governments, business and public organizations in achievement of global ecologi-cal efficiency, the formation of ecologically focused model of economy adopted in the 21st century as a model of "green" economy. However, despite the in-ternational activity of the countries, science and busi-ness, a comprehensive scientific analysis showed dis-appointing results of strengthening modern degradation processes in biosphere. The "green" industrial revolu-tion which is developed now in the world is intended to connect the potential of economic growth with inten-tions of essential reduction of load on the planet eco-systems. It is proved that "green" economy model which is actively spread in industrially developed countries of the world combines a limited economic growth and safe, careful attitude to natural processes. Using the methodology of the system socio-natural approach (overcoming a narrow framework of a socio-economic research method) it is defined that "green" economic activity is implemented due to development of the innovative technologies and technosphere sub-stances developed according to market laws in accor-dance with corporate business interests. The conclusion is drawn that expansion of artificial processes and sub-stances due to technocratic-cantered liberal economic activity leads to increase of technogenesis of socio-biospheric evolution to more distancing of modern society from natural environment. Therefore the world community when developing programs of a new "green" paradigm of economic activity (as part of the concept of sustainable development) needs to prove exhaustively scientifically how socially and economi-cally responsible and whenever possible with the min-imum damage to the biosphere to combine expansion of technogenic processes with the developing natural life.
ISSUES OF INNOVATIVE ACTIVITY INVESTMENT AT THE ENTERPRISES OF HOUSING AND COMMUNAL SERVICES
Authors: Ерохин Дмитрий , Erokhin Dmitriy
Published: May 2017

In the conditions of investment resource limitation the choice of innovative projects for their further fi-nancing is an important and urgent task. It fully be-longs to the most complex and problematic sector of housing and communal services (HCS) where for dec-ades innovations were ignored. Problems of develop-ment of housing and communal services are com-pounded by the fact that the technological, economic, organizational and social problems connected with outdated technical and technological base, continuous insufficient funding and reforming intertwine here. The paper proposes some practical approaches to selection of innovative projects, correlation of the expenses which are required for their realization and the received results.
-DIMENSIONAL FINITE ELEMENT FOR MODELLING THERMAL, ELASTIC AND THERMOELASTIC COMPONENTS IN THE COUPLED PROBLEM OF FRICTION UNITS THERMOELASTICHYDRODYNAMICS
Authors: Зернин Михаил , Zernin Mikhail , Рыбкин Николай , Rybkin Nikolay
Published: May 2017

The scheme for the solution of the coupled problem of friction units thermoelastichydrodynamics is given. It is noticed that one of the main ways for decreasing labor input of the task solution may be the choice of the rational finite element providing decision accuracy at a big aspect ratio. Twenty-nodal three-dimensional finite element is chosen and in this finite element not only second order joint shape functions but also the third order out-of-node not joint shape functions are used. By using some test examples for temperature, elastic and thermoelastic problems the advantages of such quasi-joint finite elements in comparison with joint ones are shown.
INCREASING THE EFFICIENCY OF PUBLIC ADMINISTRATION IN RUSSIA BASED ON INTRODUCTION OF THE "ELECTRONIC GOVERNMENT" CONCEPT
Authors: Логвинов Константин , Logvinov Konstantin
Published: May 2017

Now the process of information and communica-tion technologies introduction in the activity of public authorities goes beyond the framework of some infor-matization programs and projects and becomes a driv-ing transformation force of both the organization of public authorities work, and approaches to execute state functions in general. At the same time there is lack of systemacity and integral regulation of using information technologies in public administrative activity, uncertainty and discrepancy of some provisions of the legislation, lack of the uniform concept of "the electronic government".

Using a generalization method, comparative and formal-logical approaches, the article attempts to represent a complex attitude towards the problem of "electronic government" formation in the Russian Fed-eration as one of possible instruments of increasing public administration efficiency. Studying a definition of "the electronic government" has allowed to formu-late an author's interpretation of this term, to systemat-ize and generalize its functioning principles, and also to plan the possible directions of solving the organiza-tional and legal problems connected with the develop-ment of this concept in the Russian Federation.
IDENTIFICATION OF OPPORTUNITIES FOR INCREASING COMPETITIVENESS OF HIGHER EDUCATION INSTITUTION IN MODERN CONDITIONS
Authors: Мельковская Ксения , Myelkovskaya Ksyeniya
Published: May 2017

The paper aims at developing the system approach to management process of competitiveness of higher education institution for increasing the choice efficiency and application of its progressive development strategy.

Significant results of the scientific research:

- an idea of the concept of higher education insti-tution competitiveness, its key components and fea-tures is formed, and also the main approaches to de-termination of its level are identified;

- the complex technique of competitiveness as-sessment of higher education institutions within the region is developed;

- approbation of the developed technique of com-petitiveness assessment of higher education institution based on materials of FSBEI HE "Bryansk State Tech-nical University" is carried out.

Scientific novelty of the research consists in de-velopment of theoretical-methodical concepts and practical recommendations for increasing management efficiency of higher education institution competitiveness by carrying out a complex assessment of its level.

Use of the main results of scientific research in practice of competitiveness management of a higher education institution allows to reveal shortcomings of management strategy of higher education institution competitiveness and to highlight capacities for their elimination.
DEPENDENCE OF THE MEAN AND DISPERSION OF GRAIN WIDTH OF SILICON CARBIDE BLACK GRINDING POWDERS ON THE MESH SIZE OF A PASS SIEVE
Authors: Носенко Владимир , Nosenko Vladimir , Александров Алексей , Aleksandrov Aleksey
Published: May 2017

Silicon carbide black grinding powders 54CF180-F36, mass-produced at Volzhsky Abrasive Plant are studied. Powders are screened into fractions according to GOST R 52381. Measurement of a grain width of each fraction was carried out by means of a photometric method using specially developed soft-ware. For the vast majority of fractions the grain width follows the normal distribution law. The deviation of the grain width from the normal law can be observed at the fractions settled on the second sieve and the pallet. With decreasing the nominal mesh size of a pass sieve in each grit size the arithmetic mean of grain width of the main fraction decreases, dispersion reduces from the fraction settling on the second sieve to the fourth and increases at the fraction settling on the pallet. In case of the identical mesh size of a pass sieve the mean and dispersion of grain width fraction increase with grinding powder grit increase. For each grit size the functional dependences of the mean and dispersion of grain width fraction on a mesh size of a pass sieve are established.
FORMATION OF THRESHOLD VALUES OF INDICATIVE INDICATORS OF NATIONAL ECONOMIC SECURITY
Authors: Сидоренко Андрей , Sidorenko Andrey
Published: May 2017

It provides an overview of various approaches to formation of threshold values of economic security indicators; disadvantages and "weak" points of the existing systems are revealed. The most optimum ap-proach which is based on the method of indicative analysis is highlighted. Threshold values of the main indicators of economic security of the Russian Federa-tion at the national and regional levels are calculated; the examples of their definitions and justifications are given. The following indicators are considered: ratio of external debt to GDP; the relation of the resources in-volved in a shadow turn to GDP; ratio of per capita income to the subsistence minimum. An approach to clustering of regions of the Russian Federation on thre-shold values of indicators of economic security is of-fered. The following features can be selected among the main features of clustering: climatic conditions, degree of territory development, structure of industrial production in the area, provision of the territory with its own mineral resources, strength of logistic territory’s links with other areas, development of scientific schools and scientific potential of the territory, devel-opment of higher education, level of development and orientation of the structure of industrial production in the area, export potential of the territory, geographical location of the territory, degree of population areas, production capacity and financial support of the territory, age composition, etc.
INCREASE OF LABOUR PRODUCTIVITY IN THE RUSSIAN FEDERATION AS THE MAIN FACTOR OF ECONOMIC GROWTH
Authors: Стрижакова Екатерина , Strizhakova Ekaterina , Стрижаков Дмитрий , Strizhakov Dmitriy
Published: May 2017

Increase of labor productivity problems is consi-dered. The main opportunities of implementation of the Russian President's Decree №596 of May 7, 2012 "On the long-term state economic policy" made towards improving labor productivity are analyzed, the main problems are identified. Using calculations based on "Long-term plan for social and economic development in the Russian Federation until 2030" it is shown that achievement of necessary growth of productivity at preservation of the current technological level is almost impossible, and growth of productivity is based more now on decreasing of the number of working population. The calculated advance coefficient of the coun-try’s economy as a whole and for the processing pro-duction has made it possible to analyze the size of the possible economy of means received as a result of la-bor productivity increase. Labor undervaluation in the country in comparison with the western countries is a serious shortcoming. The main directions of labor productivity are shown; techniques according to which there is a possibility of increasing labor productivity within implementation of the President's Decree are presented.
THE CONCEPT OF TECHNOLOGICAL ORDER AS THE MAIN DIRECTION OF THE THEORY OF LONG WAVES IN ECONOMY
Authors: Таранов Александр , Taranov Aleksandr
Published: May 2017

The article deals with the concept of technological order as urgent and empirically justified continuation of the known theory of long waves in economy. The theory of long waves allows to predict world economic crises and economic growth at the empirical level for 50 years. Genesis of long waves theory by means of retrospective author's classification of long waves theo-ries according to technological, economic, institutional, administrative and social features is analyzed. The main group of authors who have created modern and urgent theory of long waves checked by time and strengthened by empirical calculations is: N.D. Kon-dratiev, G. Mensh, J. Dosi, Sh. Perez, S.Yu. Glazyev. The academician Glazyev has formed the concept of the technological order which is empirically proved continuation of the long waves theory. In this concept the main statements-laws, and the need of methodological approaches for technological, economic, institutional, administrative and sociological areas are revealed. An obvious property of the technological coherence of productions is considered. The logic of formation and interaction of technological units is described in detail. The conclusions are drawn about the presence of technological order. The technological innovations defining the core formation of technological way and revolutionizing technological structure of economy have received the name "key factor". Such factor now and for the next 50 years is nanotechnologies. Conclusions are drawn concerning the main property of the technological order which is a self-reproducing integrity because of that technical development of economy is only possible by consecutive change of technological orders.
PROCESS OF MANAGEMENT DECISION-MAKING AT THE REGIONAL LEVEL ON THE BASIS OF INFORMATION ADVISING SYSTEM
Authors: Аверченкова Елена , Averchenkova Elena
Published: May 2017

Author's experience of studying of managerial de-cision-making features by managers of the regional government on the example of the Bryansk region is presented in the article, the information approach al-lowing to increase efficiency of decision-making on the basis of information advising system is offered. The author defines decision-making process at the regional level as a cyclic sequence of managers’ ac-tions of the regional government aimed at solving tasks. The assessment of features of managerial deci-sion-making at the regional level was carried out by direct observation method. Labor duties, main functio-nality, a zone of managers’ responsibility of elementa-ry, middle and top management of the Government of the Bryansk region have been studied for this purpose. So, in process of management decision-making at the regional level managers should rely on own profes-sional skills, last experience, intuition. Information, which is a basis for decision-making, is formed by the external environment, and, respectively, is characte-rized by increased complexity, heterogeneity and dis-crepancy. When tasks are difficult and vaguely formu-lated the reliance only on intuition increases the risk of incorrect or non-optimal decision-making. Thus, auto-mation of decision-making support is the way of opti-mization of administrative activity. Use of the information advising system is defined by the author as a science-practical approach with support of decision-making at the regional level because it is based on processing of a large amount of information using statistical methods, method of expert evaluations, fuzzy sets, etc. Thus, formation of a management decision com-plex proposed by the information advising system al-lows to increase the accuracy and reliability of recom-mendations, and favorably differs from the decisions made by means of the traditional methods based on an intuition of the managing director or on a concept of "common sense".
Cognitive Aspect of the Art History Terms Study
Authors: Миньяр-Белоручева  , Minyar-Belorucheva A.
Published: May 2017

The language of Art History and the change of worldviews have always intertwined and determine each other. Art History is the entity unity of art theory, history and criticism. Art History as any academic discipline has its

own subject, object and terminology. The terms of Art History, contributing to the creation of a coherent pattern of art development, have three stages in their study. The stages of the analysis of the subject-specific Art History terms coincide with the paradigm shift that requires the creation of modern research techniques. However, with its introduction the new paradigm does not change the subject of the study, but the facets of the analysis putting in the focus of academic interests new aspects that have previously been beyond the purview of scholars. The terms of Art History are either composed deliberately or develop from the lexical units of natural languages. A cognitive approach to the study of subject-specific Art History terms gives the possibility to take them as signs through which occurs the verbalization of academic concepts and creation a conceptual model of the world of art.
Social Advertising: Why There Is No Mass Character And Regularity?
Authors: Калмыков  , Kalmykov S. , Савельева  , Saveleva Olga
Published: May 2017

In this article causes stopping the social advertising development are analyzed. Specific-historical, financial, scientific and national aspects are explored. Social advertising theoretical-methodological basis development, sociological researches results reliability provision and social advertising research results supplied contents expansion offers are created. Specifics of its effect on target audience is showed and paid attention to commercialization tendency. Social advertising sphere development structural decision based on domestic and foreign experience analysis is formulated. Social advertising practice national-public variant (full time) structuring realization features, its main directions, universal offer for projects accompaniment of social advertising in various actual directions of social sphere are considered. Relationship predictable character and federal and regional levels social advertising activity creative functions contents are formulated.
Modeling of Wastewater Treatment Process in a Flotation Setup with Ejection Aeration System Having a Disperser
Authors: Антонова  , Antonova E.
Published: May 2017

The mathematical modeling of flotation process has been considered in this paper. It has been pointed out that in the event when there are different types of pollutants in water the generation of bubbles with wide size-consist is needed. A flotation setup with ejection aeration system having a disperser that allows generate the bubbles which size-consist is characterized by several sets with their own values of average diameters is considered. The mathematical model for flotation process description taking into account the division of bubbles into several groups in sizes and hydrodynamic situation in flotation chambers has been proposed. Based on proposed model have been obtained other models describing extraction of certain waste, considering their properties, in such a case the initial model has been complemented by stages of other processes: settlement stage during flotation of suspended substances with density higher than water density, self-floating stage during flotation of contaminations with density less than water density, and reverse stages during flotation of hydrophobic-hydrophilic contaminations. The example of time definition for the process of water treatment from suspended substances and oil products has been presented. It has been demonstrated that it is possible to considerate the two-chamber flotation setup with ejection aeration system having a disperser as a sequence of reactors providing ideal mixing and displacement. Taking into account the equations for the reactors providing ideal mixing and ideal displacement, and the proposed models for description of process passing in cameras, have been received dependences for determination of concentrations and cleaning time in each camera. The importance of mathematical modeling for flotation setups designing has been pointed out. Application of scientifically based approach at design allows create setups having bigger profitability and compactness at achievement of the required efficiency.
NPVO Refractometer for diffusing substance investigations
Authors: Якимова Мария , Yakimova Mariya , Алехнович Валентин , Alekhnovich Valentin , Григорьянц Александр , Grigoryants Aleksandr
Published: May 2017

The paper deals with the use of refractometry for the analysis of strongly scattering materials. The peculiarities in the interpretation of measurement results, and in particular, the simulation of attenuation factors of a flat and damped wave for the use in the equation of coupling are considered. Besides, there is investigated a degree of the influence of different parameters (concentration of particles and their parameters) upon results of experiments which will improve accuracy and reliability of experiments. The results of experiments are obtained with the aid of NPVO refractometer on strongly scattering samples with a calibrated composition. The processing of experiment results carried out with the use of Mi scattering factors and scattering factors of standing wave allows estimating in what cases it makes sense to use more complex expressions for a damped wave and in what cases may be used Mi factors.
Methods of Assessment of Efficiency of Introduction of Model Training and Individual Socio-Psychological Support of Students with Disorders of the Musculoskeletal System
Authors: Ярая  , Yaraya Tatyana , Рокотянская  , Rokotyanskaya Lesya
Published: May 2017

The article presents the criteria, indicators and methods of evaluation of the structural components of models of learning and support students with disorders of the musculoskeletal system: personnel potential of the educational environment, material and technical and methodical equipment of educational process, the organization of interaction of subjects of educational process, including customers of educational services. To assess are two forms: standard and specialized educational environment. The tools that were used to evaluate the effectiveness of the implementation of the presented forms of the model were developed taking into account the criteria and indicators outlined in the Interagency comprehensive plan of measures to ensure the accessibility of professional education for disabled persons and persons with disabilities for 2016 – 2018. The study presents criteria and indicators was carried out using the methods of analysis of the internal environment, expert assessments, comparative analysis and monitoring method.
Formation of Quality Competence of Future Teachers and Heads of the Educational Organizations at University
Authors: Алдошина  , Aldoshina M. , Гришина
Published: May 2017

In the conditions of system transformations of an education system the contradiction between requirement of society for the teachers of a new formation acting as the guarantor of quality education, and a fragmentariness of the quality training of students at university which isn’t providing fully the social order convinces of need of formation at students of evidence-based, integrative knowledge in the fi eld of quality assessment as element of professional competence. In the article results of modeling of process of formation of quality competence of future teachers and heads of the educational organizations are stated. At the same time pedagogical modeling in the context of the publication is understood as development of the purposes (the general idea) of creation of required pedagogical process and the main ways of their achievement. At creation of model authors were guided by the experience of pedagogical researches, general scientifi c requirements relating to process of modeling and personal practice of formation the quality of competences of university. The presented model gives the chance of transfer of the obtained data in real practice by means of adaptation to specifi c objectives of quality education in the conditions of implementation of professional educational programs of preparation of pedagogical shots.
Students’ Achievements Level Monitoring As a Factor of Quality of Professional Education
Authors: Романченко  , Romanchenko M.
Published: May 2017

In the article the creation of the system of monitoring of quality of training of specialists is investigated. The priority directions investigating eff ectiveness of professional education as system training of the popular expert are considered. The purpose of carrying out monitoring of level of achievements of students which is expressed in creation of the mechanism of management of the system of researches of educational achievements directed to reliable estimation and development of students is formulated. On the basis of the analysis of the generalized, private, special and marked out results received during monitoring optimum expansion of quantitative and qualitative criteria, the humanitarian and natural-science methods of a research providing a combination and comparison of the results received by various researches is off ered. The need of introduction of new criteria is proved. The useful recommendations submitted on a solution of the problem of formation of the procedure of monitoring of level of achievements of students as indicator of quality of education are off ered. The importance of work consists in a possibility of synthesis of experience for the purpose of use of secondary professional education by educational institutions.
Special Features of Intercultural Competence of Futures Nurses According to the Requirements of Federal State Educational Standard of Vocational Secondary Education
Authors: Лебедева  , Lebedeva O. , Казановская  , Kazanovskaya N.
Published: May 2017

The notion «nurses’ intercultural competence» is introduced in the article. Its compositions such as general cultural and communicative competences are defi ned according to the requirements of FSES of vocational secondary education. Pedagogical conditions of the development of future nurses’ intercultural competence, such as multicultural education environment of college and interdisciplinary connections of the humanities and professional subjects, are considered.