bluuebunny/crossref_metadata_2025 huggingface dataset:
Oral cancer - knowledge and perception of the population in the screening program during world oral, head and neck cancer awareness week
Authors: Andabak Rogulj Ana , Brailo Vlaho , Horvat Kristina , Lončar Brzak Božana , Vidović Juras Danica , Alajbeg Ivan , Muhvić Urek Miranda , Glažar Irena , Škrinjar Ivana
Published: June 2022

Aim: Oral cancer (OC) is characterized by a high mortality rate because most cases are diagnosed at an advanced stage. The purpose of this study was to assess population knowledge at screening for OC, risk factors, prevention, and early detection, and to determine whether factors such as level of education and gender affect knowledge of the respondents. Material and Methods: The study was conducted at the School of Dental Medicine University of Zagreb and the Faculty of Dental Medicine University of Rijeka using the attached questionnaire. Participants were patients who arrived for free screening examinations during World Oral, Head and Neck Cancer Awareness Week from 22–28 April 2017, and answered survey questions on their knowledge of OC. Results: One hundred and eighty-five participants attended the screening event. Some participants did not answer certain questions, so the statistics with each question were made only for those respondents who answered that question. Screening event has included 99 (57.9%) females and 72 (42.1%) males (14 participants did not answer). The median age of participants was 67 years. The majority of participants (115; 80.4%) had heard about OC, but had not heard about nor previously attended OC screening examination (71 or 51.1% of females and 123 or 86.6% of males). No significant difference between genders and between participants with different levels of education was observed. The majority of participants (111;79.3%) knew that smoking was a risk factor for OC, and believed that their risk of getting OC was similar to other people in their age group and gender. Conclusions: Our results show that most participants have heard about OC, but have not heard about nor previously attend OC screenings. Future programs should be directed more to the high-risk population in order to achieve early detection and treatment of OC.
Obilježja obitelji djece uključene u psihijatrijski tretman
Authors: Paradžik Ljubica , Novak Miranda , Ferić Martina
Published: June 2022

Cilj: Cilj ovog rada je analizirati obilježja obiteljskog okruženja, uključujući zaštitne i rizične čimbenike djece uključene u psihijatrijski tretman zbog poteškoća mentalnog zdravlja. Ispitanici i metode: Istraživanje je provedeno na kliničkom uzorku od 112 sudionika – 56-ero djece u dobi od 12 do 19 godina te 56 njihovih roditelja/skrbnika. Uz obilježja roditelja/skrbnika, ispitani su rizični i zaštitni čimbenici u obitelji te čimbenici rizika vezani uz karakteristike djeteta te karakteristike obitelji. Ciljane varijable ispitane su Upitnikom obiteljske otpornosti te Listom za procjenu razvojnih rizika djeteta koja se sastoji od procjene obiteljskih okolnosti i obilježja roditelja kao čimbenika razvojnog rizika djeteta te procjene obilježja djeteta i njegovog ponašanja. Uz to, prikupljeni su i podatci iz anamneza vezani uz kliničke dijagnoze djece te etiologija specifičnog poremećaja kod svakog uključenog djeteta.Studija je provedena u okviru projekta „Specifična obilježja obitelji u riziku: doprinos planiranju kompleksnih intervencija – „FamResPlan“ (HRZZ IP-2014-09-9515).Rezultati: Obitelji djece s poteškoćama mentalnog zdravlja karakterizira izostanak podrške okoline, prisutnost emocionalnih poteškoća roditelja zbog obiteljskog stresa te psihička bolest ili, pak, neliječena psihička bolest roditelja. Od 56-ero djece uključene u istraživanje 49-ero je imalo internalizirane probleme, a sedmero mješovite internalizirane i eksternalizirane probleme. Zaključci: Obilježja obitelji djece uključene u psihijatrijski tretman sugeriraju da je potrebno osigurati prikladnu i sveobuhvatnu podršku roditeljima u ranoj dječjoj dobi kako bi se prevenirali kasniji poremećaji mentalnog zdravlja djece i mladih.
Management of Strategic Competitiveness of Industrial Enterprises: Assessment, Implementation of Technological and Managerial Innovations
Authors: Kalynychenko M. P.
Published: June 2022

The relevance. In the modern VUCA-world, instability, uncertainty, complexity and ambiguity in the external environment of industrial enterprises are growing rapidly. Top management is required to produce and implement innovations, including managerial and technological ones, formed on the basis of a sustainable development model.

The purpose of the article is to develop scientific and methodological approaches to managing the competitiveness of an industrial enterprise.

Objectives: to develop a methodological approach to assessing the competitiveness of an industrial enterprise, taking into account the nature of economic relations between an industrial enterprise and its stakeholders; substantiate the feasibility of using technological and managerial innovations as factors in increasing the competitiveness of an industrial enterprise.

The research methodology includes a combination of systemic, logical, empirical and comparative methods of analysis; of static and dynamic approaches, which made it possible to comprehensively consider the processes of forming the competitiveness of industrial enterprises. Also, the article used general scientific methods of analysis and synthesis, ascent from the abstract to the concrete and from the general to the particular, as well as the methods of statistical and economic analysis.

Results. An approach to understanding the competitiveness of enterprise through the prism of the «stakeholders ‒ industrial enterprise ‒ stakeholders» system is proposed. It is substantiated that the subject of management is subject to the need to establish and maintain compliance, the relationship between the set of parameters (indicators) of the competitiveness of an industrial enterprise and their respective interests with the parameters and interests of stakeholders. A scientific and methodological approach to the integral assessment of the competitiveness of an enterprise has been developed, and the priorities for managing the CP as an innovative process have been justified.

Conclusion. Testing the proposed approach to the integrated assessment of the competitiveness of Mining Equipment LLC showed that the value of this assessment is directly dependent on the consistency of joint interests.
Navigating the Credibility of Web-Based Information During the COVID-19 Pandemic: Using Mnemonics to Empower the Public to Spot Red Flags in Health Information on the Internet
Authors: Stokes-Parish Jessica
Published: June 2022

Misinformation creates challenges for the general public in differentiating truth from fiction in web-based content. During the COVID-19 pandemic, this issue has been amplified due to high volumes of news and changing information. Evidence on misinformation largely focuses on understanding the psychology of misinformation and debunking strategies but neglects to explore critical thinking education for the general public. This viewpoint outlines the science of misinformation and the current resources available to the public. This paper describes the development and theoretical underpinnings of a mnemonic (Conflict of Interest, References, Author, Buzzwords, Scope of Practice [CRABS]) for identifying misinformation in web-based health content. Leveraging evidence-based educational strategies may be a promising approach for empowering the public with the confidence needed to differentiate truth from fiction in an infodemic.
Association of HLA Mismatches and Histology Suggestive of Antibody-Mediated Injury in the Absence of Donor-Specific Anti-HLA Antibodies
Authors: Senev Aleksandar , Lerut Evelyne , Coemans Maarten , Callemeyn Jasper , Copley Hannah Charlotte , Claas Frans , Koshy Priyanka , Kosmoliaptsis Vasilis , Kuypers Dirk , Sprangers Ben , Van Craenenbroeck Amaryllis , Van Loon Elisabet , Van Sandt Vicky , Emonds Marie-Paule , Naesens Maarten
Published: June 2022

Background and objectives

The histology of antibody-mediated rejection after kidney transplantation is observed frequently in the absence of detectable donor-specific anti-HLA antibodies. Although there is an active interest in the role of non-HLA antibodies in this phenotype, it remains unknown whether HLA mismatches play an antibody-independent role in this phenotype of microcirculation inflammation.

Design, setting, participants, & measurements

To study this, we used the tools HLAMatchmaker, three-dimensional electrostatic mismatch score, HLA solvent accessible amino acid mismatches, and mismatched donor HLA–derived T cell epitope targets to determine the degree of HLA molecular mismatches in 893 kidney transplant recipients with available biopsy follow-up. Multivariable Cox proportional hazards models were applied to quantify the cause-specific hazard ratios of the different types of HLA mismatch scores for developing antibody-mediated rejection or histology of antibody-mediated rejection in the absence of donor-specific anti-HLA antibodies. In all survival analyses, the patients were censored at the time of the last biopsy.

Results

In total, 121 (14%) patients developed histology of antibody-mediated rejection in the absence of donor-specific anti-HLA antibodies, of which 44 (36%) patients had concomitant T cell–mediated rejection. In multivariable Cox analysis, all different calculations of the degree of HLA mismatch associated with developing histology of antibody-mediated rejection in the absence of donor-specific anti-HLA antibodies. This association was dependent neither on the presence of missing self (potentially related to natural killer cell activation) nor on the formation of de novo HLA antibodies. Also, glomerulitis and complement C4d deposition in peritubular capillaries associated with the degree of HLA mismatch in the absence of anti-HLA antibodies.

Conclusions

The histology of antibody-mediated rejection and its defining lesions are also observed in patients without circulating anti-HLA antibodies and relate to the degree of HLA mismatch.
Review Replacement Theory
Authors: Achuthan Prof. M. Radh
Published: June 2022

n/a
Challenges encountered in the Implementation of Enterprise Resource Planning ERP in infrastructure contracting companies emphasis on business processes integration
Authors: Fatfat Majed Abdel Rahman
Published: June 2022

The purpose of this paper is to present an integrative and detailed review of the critical factors of enterprise resource planning (ERP) that influence effectiveness of business process integration. Organizations' use of Enterprise Resource Planning (ERP) systems has changed the way they provide information systems. The research applied quantitative research method to examine the current study which analyzing the integrative and detailed review of the critical factors of enterprise resource planning (ERP) that influence effectiveness of business process integration. The researcher distributed 180 questionnaires among several projects in Qatar, however it was able to gather only 168 questionnaires out of 180 questionnaires. The findings revealed that all independent variables are positively and significantly influence dependent variable, moreover it was found the highest value was between PMIS and ERP integration, on the other hand the lowest value was for between control environment and ERP integration.
On a subclass of meromorphic functions with positive coefficients defined by rapid operator
Authors: Venkateswarlu B. , Thirupathi Reddy P. , Ingle Rajkumar N. , Sreelakshmi S.
Published: June 2022

In this paper, we introduce and study a new subclass of meromorphic univalent functions defined by Rapid operator. We obtain coefficient inequalities, extreme points, radius of starlikeness and convexity. Finally we obtain partial sums and neighborhood properties for the class ∑*p(γ,κ,μ,θ)
Near-Zumkeller numbers
Authors: Patodia Harish , Saikia Helen K.
Published: June 2022

A positive integer n is called a Zumkeller number if the set of all the positive divisors of n can be partitioned into two disjoint subsets, each summing to σ(n)/2. In this paper, Generalizing further, near-Zumkeller numbers and k-near-Zumkeller numbers are defined and also some results concerning these numbers are established. Relations of these numbers with practical numbers are also studied in this paper.
Evaluation of Serum IL-33, IL-5 and Trace Elements Levels among Asthmatic Patients
Authors: Iqbal Mayada Noori , Yosif Sura O. , Muhsin Jasim Mohammed , Samanje Jaleel
Published: June 2022

The precise relationship between interleukins-33 and IL-5, as well as some trace elements and asthma, is unknown. The target of research was to compare and link the above-mentioned serological parameters in asthmatic patients and healthy controls. In 69 asthmatic patients and 35 healthy controls, serum levels of IL-33, IL-5, zinc, copper, iron, total IgE, Forced expiratory volume (FEV) and Forced expiratory volume (FEV) were compared. Spirometry was used to assess the (FEV) and (FVC) in asthmatic patients, as well as their age and body mass index (BMI). When asthmatic patients were matched to controls, mean levels of IL-33, IL-5, and total IgE appeared highly significant difference (p < 0.001). There was a substantial decline in zinc levels in the asthmatic group, but no significant drop in Copper levels. There was also a statistically significant difference in high Iron mean levels among asthmatic patients. In addition, the findings revealed a significant positive correlation between Iron and IgE levels in patients and the levels of (IL-33 and IL-5), plus a significant negative correlation with Zinc levels. Only Copper had no relationship with the interleukins studied. IL-33, also known as IL-5, is a novel inflammatory marker implicated in asthma progression by interacting with IgE, Zinc, Iron, but not Copper levels. As a result, it could be a one-of-a-kind therapeutic target in these patients.
Response Surface Methodology for Optimization Membrane Disruption Using Thermolysis in Lipase Lk2 and Lk3
Authors: Haryati Titin , Widhiastuty Made Puspasari , Warganegara Fida Madayanti , Akhmaloka
Published: June 2022

Lk2 and Lk3 were thermostable recombinant lipase and highly expressed in Escherichia coli BL21 (DE3). However, Lk2 and Lk3 accumulated as an inclusion body. To further characterize both recombinant lipases, the soluble enzyme must be obtained first. This study aimed to optimize the disruption of the cell membrane in order to obtain soluble and active lipases. The effects of temperature lysis, pH, and SDS concentration on lipolytic activity Lk2 and Lk3 were investigated using a three-factor Box-Behnken design response surface methods. The optimum condition for the temperature variables at 50°C, pH 8, and 0.34% SDS which gave a lipolytic activity of 0.9 U for Lk2. Meanwhile, Lk3 lipolytic activity of 0.9 U obtained at the temperature of 50°C, pH 8, and 0.1% SDS. This result showed efficient one-step membrane disruption methods using thermolysis with addition of a low concentration of detergent at pH 8. The methods used were effective and applicable in the production of active and soluble thermostable recombinant lipase.
Characterization of Uropathogenic Pseudomonas aeruginosa: Serotypes, Resistance Phenotypes, and Virulence Genotypes
Authors: Elbargisy Rehab Mohammed
Published: June 2022

Pseudomonas aeruginosa is a major cause of urinary tract infections. This organism has extended resistance to antimicrobials along with multiple virulence factors, making it difficult to treat. In this study, 49 isolates from urine samples were identified as P. aeruginosa and serotyped by the slide agglutination method. The sensitivity of isolates against 10 antipseudomonal drugs was determined. Phenotypically, lipase, protease, hemolysin, and biofilm production were detected. Genes for the type III secretion system, elastase B, and exotoxin A were detected by PCR. Serotype O11 was the most predominant serotype among test isolates. High levels of resistance were observed against ceftazidime, cefepime, piperacillin, and piperacillin/tazobactam while 10.2% of isolates were resistant to amikacin. MDR was detected in 20.4% of the isolates and was significantly associated with strong biofilm producers. About 95.9% and 63.3% of P. aeruginosa isolates had proteolytic and lipolytic activity, respectively. Among the genes detected, the exoY gene was the most prevalent gene (79.6%), while the exoU gene was the least frequent one (10.2%). toxA and lasB genes were amplified in 63.27% and 75.5% of the isolates, respectively. In addition, the exoU gene was significantly associated with MDR isolates. The high incidence of exoS, exoT, exoY, lasB, and toxA genes in uropathogenic P. aeruginosa implies that these genes can be considered markers for virulent isolates. Furthermore, the coexistence of exoU and exoS genes, even in 6% of isolates, poses a significant treatment challenge because those isolates possess both the invasive and cytotoxic properties of both effector proteins.
Production of a Polyketide Pigment by Fusarium chlamydosporum
Authors: Thomas Tessy Anu , Tirumale Sharmila
Published: June 2022

The present study was focused to study the production of secondary metabolite by the fungus, F. chlamydosporum on a non-defined medium with less concentration of nitrogen; the organic nitrogen source being peptone and beef extract. In this context, we have been successful in extracting a polyketide pigment from the fungus by using the homogenization technique. The pigments thus extracted were subjected to various purification techniques via thin layer chromatography, column chromatography, UV-visible spectrophotometry, fourier-transform infrared spectroscopy and finally molecular determination by liquid chromatography coupled to tandem quadrupole mass spectrometry (LC-MS-MS). The polyketide red pigment was finally characterized and identified to be fusarubin following which its cytotoxicity was evaluated in vitro by using normal lung fibroblast cell lines (MRC-5). In the verge of researchers identifying novel compounds for various applications, the production of fusarubin by the fungus can be a major breakthrough as fusarubin has been investigated to exhibit many pharmacological activities. Though fusarubin is reported to be produced by other Fusarium species, this is the foremost study on the production of fusarubin by F. chlamydosporum; the composition of the culture medium is also unique. The production of this polyketide probably correlates in the pathogenesis of F. chlamydosporum as studies comment on this fungus as an opportunistic pathogen.
Control of Tomato Wilt Disease Fungus Fusarium oxysporum f.sp. Lycopersicon by Single or Combine Interaction of Mycorrhiza, Trichoderma harzianum, and Effective Microorganisms (Microbial Blend)
Authors: Alshammari Nawaf I. , Bairum Randa S. , Sulieman Abdel Moneim E. , Jamal Arshad , Alamoudi Muna , Elamin Hassan B. , Veettil Vajid Nettoor
Published: June 2022

The tomato plant is usually infected with various pathogens such as pests, bacteria, and different mycoflora. In this investigation, Tomato plant cultivar Beeli was pathogenized with Fusarium oxysporum f.sp. Lycopersicon (FOL1) fungi. The FOL1 fungus was controlled by inoculating the pathogenized Tomato plants with each one of the biocontrol microorganisms, such as Arbuscular mycorrhiza (AM), Trichoderma harzianum (T. harzianum), and microbial blend, named as Effective Microorganisms (EM). Consequently, the effect of these biocontrol microorganisms on the amount of chlorophyll, proteins, and defense enzymes of the Tomato plant was estimated. The results showed that the AM, T. harzianum fungi, and “EM” gave similar ameliorative effects. However, there are regulated increasing content of chlorophyll, proteins, and the activities of many protecting compounds such as acid invertase peroxidase. Moreover, these important plant defense mechanisms have a vital role in oxidizing phenolic compounds, which could increase antimicrobial activity. Altogether, the results demonstrate that the protein and chlorophyll are increased differently in all treatments. The protein level is the highest in FOL1 + EM treatment and the ML showed the highest level of chlorophyll.
Prevalence and Risk Factors of Staphylococcal Subclinical Mastitis in Dairy Animals of Chitwan, Nepal
Authors: Tiwari Bibas Bahadur , Subedi Deepak , Bhandari Suman , Shrestha Prajjwal , Pathak Chet Raj , Chandran Deepak , Pandey Gita , Mohankumar Pran , Dhama Kuldeep
Published: June 2022

Subclinical mastitis (SCM), the asymptomatic inflammation of breast tissue, is the most common form of mastitis in livestock. SCM prevalence and risk factors in dairy animals in Western Chitwan, Bagmati Province, Nepal, were the primary objectives of this study. Out of 243 dairy animals, 104 representing 42.8% were positive for SCM in the California mastitis test (CMT) in the study area. At the quarter level, out of 972 active quarters tested for SCM, 188 (19.3%) were positive to CMT test. The prevalence of Staphylococcal SCM was 39.92% (97/243) and 18.21% (177/972) at animal level and quarter level, respectively. Coagulase Negative Staphylococcus (CNS) (46.33%) was the most prevalent Staphylococcus to cause SCM at quarter level. While at animal level, SCM due to occurrence of both S. aureus and CNS (36.08%) in an individual was more common. High susceptibility towards Amikacin, Ceftriaxone and Gentamicin was seen against both isolates. Low resistance against Amikacin and Ceftriaxone was seen against both isolates. Ciprofloxacin (41.2% vs 27.4%) and Gentamicin (37.8% vs 23.2%) were more resistance towards CNS whereas Enrofloxacin (41.1% vs 25.2%) and Tetracycline (36.8% vs 15.1%) were more resistant towards S. aureus. Older aged, multiparous and late lactating animals had the highest prevalence of staphylococcal SCM i.e., 58.1%, 56% and 52.6%, respectively. The study concludes that there is a high prevalence of Staphylococcal SCM in Western Chitwan, Nepal. CNS is the most common mastitis pathogen. Increased antimicrobial resistance to S. aureus and CNS could be the result of the indiscriminate use of antibiotic drugs without an antibiotic susceptibility test (AST). This study emphasizes the importance of ongoing antibiotic surveillance, excellent farm and animal hygiene, and suitable housing and feeding management.
A Study on Analysis of Patient Food Delivery in a Multispecialty Hospital, Coimbatore
Authors: Uma Dr. V. , Suruthika T.
Published: June 2022

Abstract: Dietary department within hospital sector is responsible for complete supply of foods and feeds to patient and their family members. Any error in this department will lead to delay in patient care. In this study, the researcher analyses the food delivery system and finds out whether right food is delivered for all patient at right time. This topic is an initiative to provide suitable suggestion to overcome errors and to improve the overall food delivery standards. The data collection method was used to find the patient food delivery to the right food, right time to the patient. Time delay is calculated throughout the study to find out the reason for food delay. The purpose of the study is to improve food delivery process at hospital. Keywords: Food error, Time delay, Dietary department, Solid food, Liquid food, Package food.
Empowering comunity in creating business opportunities in Pahlawan Village, Batu Bara Regency
Authors: Sari Dian Septiana , Irawan I
Published: June 2022

The growth of small businesses plays an important role in the economic development of the community. Unfortunately, many regions are less able to develop small businesses even though their regions have various economic potentials. The purpose of this community service program was to empower rural communities in creating culinary business opportunities. This community service program was carried out by a team from the Universitas Pembangunan Panca Budi by involving the community in Pahlawan Village, Batu Bara Regency. The method used was through lectures and focus group discussions. The materials presented and discussed were business administration management and marketing management. Observation activities were carried out to evaluate the results of community service activities. The evaluation results show that the people in the Pahlawan Village need to develop alternative business strategies, improve business management, and identify various factors for marketing activities for culinary businesses.
Developing analytical skills through optimizing the learning process by science teachers in Nganjuk Regency
Authors: Yakub Pramita , Puspitawati Rinie Pratiwi , Bashri Ahmad
Published: June 2022

Based on the results of the interviews, it was found that science teachers in Nganjuk Regency did not understand and master the skills of analyzing, especially with Biology material so that there was a need for training to practice analytical skills through optimizing learning. This training activity aimed to develop analytical skills through optimizing the learning process. This training activity involved 10 junior high school teachers who are members of  the Science Subject Teacher Association (Musyawarah Guru Mata Pelajaran/MGMP) of Nganjuk  Regency. The method used was observation and data were analyzed in descriptive qualitative. The implementation of the activities were divided into three stages, namely the preparation, implementation, and evaluation stages and feedback, as well as participant responses. The results of the responses based on the questionnaire were positive with a score of 3.82, very good training material at 3.82, and very good training conditions with a score of 3.84. There was an increase in the learning analysis skills of MGMP participants with a percentage of 82.40%.
REFORMASI BIROKRASI DAN KEBIJAKAN PELAYANAN PUBLIK PADA SEKTOR PERIZINAN
Authors: Ramadhan Yoga Surya , Fitria Fitria
Published: June 2022

The writing of this article is a research using the normative method (doctrinal), which aims to describe how the direction of public service policy reform, especially in regulating the operation of permits in Indonesia. who issued the permit. Policies related to licensing issued by the government are a guide in the implementation of licensing services. Provisions regarding licensing issues are very broad because of the diversity of types of licenses issued according to the position of each agency itself, so over time there will continue to be reforms in public service policies, especially in terms of licensing policies. These reforms are of course aimed at creating the conditions for public services desired by the community, namely licensing services that are easy, fast, and efficient.
PEMBUKAAN RAHASIA MEDIS PASIEN COVID-19 SEBAGAI IMPLEMENTASI DI ERA NEW NORMAL DALAM PELAYANAN KESEHATAN
Authors: Eria Blencisca Tara , Nuriyatman Eko
Published: June 2022

Dalam era modern seperti sekarang ini, semua hal menjadi layak untuk dikonsumsi termasuk informasi kesehatan. Dalam pelayanan kesehatan dikenal adanya rahasia medis pasien, rahasia medis pasien berisi data pribadi kesehatan seseorang yang termsuk informasi yang dikecualikan untuk dapat dibuka kepada public. Namun, dalam situasi pandemic seperti sekarang segala informasi di bidang kesehatan sangat diperlukan untuk mengatasi penyebaran virus Covid-19, dalam hal ini tidak terkecuali informasi tentang rahasia medis seseorang. Dari artikel ini dapat diketahui bahwa ternyata rahasia medis seseorang dapat dibuka kepada public, hal ini dilakukan sebagai bentuk upaya pemerintah dalam mencegah penyebaran virus Covid-19. Undang-Undang tentang Kesehatan dan Praktek Kedokteran memberikan pengecualian terhadap kerahasian data pasien apabila berhubungan dengan kepentingan umum maka kerahasiaan pasien dapat dibuka kepada public. Namun, keterbukaan rahasia medis pasien Covid-19 hanya sebatas identitas lengkap sepeti nama dan alamat sebagai syarat untuk mengetahui contact tracing pasien, sedangkan mengenai riwayat penyakit yang selama ini dialami oleh pasien tetaplah menjadi ranah hukum private antara pasien dan pemberi pelayanan kesehatan, sehingga tidak dibenarkan bagi masyarakat umum untuk menyebarluaskan informasi mengenai riwayat kesehatan pasien Covid-19.
Influencing factors of short- and long-term returns on IPOs in the Chinese and the U.S. capital markets: A systematic literature review
Authors: Krug Moritz , Herberger Tim Alexander
Published: June 2022

In their studies, Loughran, Ritter, and Rydqvist (1994), Fan, Wong, and Zhang (2007), Chi and Padgett (2005) as well as Ritter (1991) show differences in the regional characteristics of underpricing and overpricing in initial public offerings (IPOs). Our study analysis the regional differences in the influencing factors of underpricing or overpricing based on a systematic literature review that is focused on the Chinese and the U.S. capital markets. Therefore, following the systematic literature review protocol, it was possible to select 38 papers published between 1988 and 2019. Our results show that stock market-specific factors are crucial for regional differentiation. Results on the correlation between stakeholder- and issuance-specific factors are at least partially contradictory. The uniformly identified correlations of stakeholder and issuance factors diverge only slightly in both markets. The investigation of the influencing factors mentioned in the studies also reveals the causal relationship that the IPO return phenomenon of underpricing is influenced by site-exclusive and site-independent factors, whereas overpricing is primarily influenced by site-independent factors. We thus close an existing research gap and satisfy an important information need of issuers and investors.
Mimicking Multiple Myeloma: the importance of the differential diagnosis
Authors: Derudas Daniele , Claudia Concu , Durzu Tania , Piras Doloretta , Nemolato Sonia , Liguori Annamaria , Simula Maria Pina , Nasa Giorgio La
Published: June 2022

Here we describe the case of a caucasian man referred to our Center for
a suspicion of Multiple Myeloma which comprehensive work-up ruled out
the presence of plasma cells neoplasm and allowed us to perform a
diagnosis of brown tumor (BT).
Evaluation of Dittrichia viscosa aquaporin Nip1.1 gene as marker for arsenic tolerant plant selection
Authors: Paolis Angelo De , Caroli Monica De , Rojas Makarena , Curci Lorenzo Maria , Piro Gabriella , Sansebastiano Gian-Pietro Di
Published: June 2022

Dittrichia viscosa (L.) Greuter is gaining attention for its high
genetic plasticity and ability to adapt to adverse environmental
conditions including heavy metals and metalloids pollution. Uptake and
translocation of cadmium, copper, iron, nickel, lead, and zinc to the
shoots have been characterized but its performance with arsenic is less
known and sometimes contradictory. Tolerance to As is not related to a
reduced uptake but the null mutation of the aquaporin Nip1.1 gene
in Arabidopsis, makes the plant completely resistant to the metalloid.
This aquaporin, localized in the Endoplasmic Reticulum is responsible
for arsenite and antimony (Sb) membrane permeation but the uptake of
arsenite occurs also in the null mutant, suggesting a more sophisticated
action mechanism than direct uptake. The DvNIP1 gene homologue is here
cloned and its expression profile in roots and shoots is characterized
in different arsenic stress conditions. The use of clonal lines allowed
to evidence that DvNip1.1 expression level is influenced by
arsenic stress. The proportion of gene expression in roots and shoots
can be used to generate an index that appears to be a promising putative
selection marker to predict arsenic-resistant lines of Dittrichia
viscosa plants.
Mark-to-Market, Loan Retention, and Loan Origination
Authors: Bleck Alexander , Gao Pingyang
Published: June 2022

We study the effects of mark-to-market accounting (MTM) for banks following the originate-to-distribute lending model. Banks have expertise in originating loans, but it is costly for them to retain the loans on their books. We study how the accounting measurement of the retained loans affects the banks’ origination and retention decisions. We show that, relative to historic cost accounting (HC), MTM has three consequences. First, it improves the accuracy of loan measurement ex post. Second, it forces banks to retain more risk exposure on their own books. Finally, it can reduce ex ante origination efforts and lower the average quality of loans in the economy.

JEL Classifications: G01; G21; G30; M41.
Heart Failure: An Underappreciated Complication of Diabetes. A Consensus Report of the American Diabetes Association
Authors: Pop-Busui Rodica , Januzzi James L. , Bruemmer Dennis , Butalia Sonia , Green Jennifer B. , Horton William B. , Knight Colette , Levi Moshe , Rasouli Neda , Richardson Caroline R.
Published: June 2022

Heart failure (HF) has been recognized as a common complication of diabetes, with a prevalence of up to 22% in individuals with diabetes and increasing incidence rates. Data also suggest that HF may develop in individuals with diabetes even in the absence of hypertension, coronary heart disease, or valvular heart disease and, as such, represents a major cardiovascular complication in this vulnerable population; HF may also be the first presentation of cardiovascular disease in many individuals with diabetes. Given that during the past decade, the prevalence of diabetes (particularly type 2 diabetes) has risen by 30% globally (with prevalence expected to increase further), the burden of HF on the health care system will continue to rise. The scope of this American Diabetes Association consensus report with designated representation from the American College of Cardiology is to provide clear guidance to practitioners on the best approaches for screening and diagnosing HF in individuals with diabetes or prediabetes, with the goal to ensure access to optimal, evidence-based management for all and to mitigate the risks of serious complications, leveraging prior policy statements by the American College of Cardiology and American Heart Association.
Physiological alteration and the expression of fibrogenesis-proinflammatory genes in hepatocellular carcinoma patients with chronic hepatitis C and onset metabolic syndrome: a preliminary report at Saiful Anwar General Hospital Malang
Authors: Susanto Hendra
Published: June 2022

Hepatocellular carcinoma (HCC) is one type of cancer that is included in the fifth order of cancer that causes death in the world. The highest incidence of liver cancer is found in men. Liver function related to the metabolism of various endogenous and exogenous substances is prone to chronic inflammatory stimulation, one of which is hepatitis C virus (HCV) infection. TGF-β1, NOX4, and TNF-α are three potential genes responsible for regulating chronic inflammation and fibrogenesis. This study aims to describe the profile of potential fibrogenesis and inflammation genes that play a role in the progression of HCC due to chronic hepatitis C. This type of research is a descriptive study with a quantitative approach that was carried out using Quantitative Real-Time PCR analysis. The results of serological tests in the male gender group showed that the average fasting body glucose level was 85.22 mg/dL, total cholesterol 242 mg/dL, triglyceride 158.44 mg/dL, HDL-C 18.56 mg/dL, and LDL-C 172 mg/dL. In the female gender group, the data obtained on average levels of fasting blood glucose 82.33l mg.dL, total cholesterol 350 mg/dL, triglyceride 181 mg/dL, HDL-C 29 mg/dL, and LDL-C 190 mg/dL. All gender groups also showed an increase in AST and ALT levels that had exceeded normal limits. The expression of fibrosis-related genes, namely TGF-β1 was 5.8x higher in male patients than female patients. The NOX4 gene also showed almost the same thing, namely, its expression level was 1.2 times higher in male patients. From the expression of the proinflammatory cytokine TNF-, it is also known that in male patients, the expression level is 2x times higher than in female patients. The difference in expression levels in the two groups involved a repressive mechanism of estrogen. Increased expression levels of TGF-β1, NOX4, and TNF- genes are thought to involve the activity of the HCV core protein, which then induces several signaling pathways such as NF-κB and SMAD3. From these results, the expression levels of TGF-β1, NOX4, and TNF- as the main regulators of chronic inflammation and fibrosis can describe the progression of HCC and can be used as initial data on the profile of inflammation and fibrogenesis in HCC cases that have previously been exposed to HCV infection.
La formación de estudiantes de posgrado. Un análisis desde sus competencias de investigación
Authors: Peinado Camacho José de Jesús
Published: June 2022

La investigación es una actividad sustantiva para mejorar la calidad de vida de las personas. Una forma de contribuir a ello desde el aula es mediante el impulso de las competencias de investigación en el estudiantado de posgrado. Y en ese sentido, el objetivo de esta investigación fue evaluar las competencias de investigación de los estudiantes de maestría y doctorado en Tecnología Avanzada del Instituto Politécnico Nacional. La metodología que se utilizó fue cuantitativa. La investigación fue no experimental con diseño transversal y su alcance fue exploratorio y descriptivo. La muestra empleada fue probabilística y estratificada. Los resultados evidenciaron que las competencias de investigación en el alumnado son sólidas. Se concluye que las competencias de investigación no se desarrollan de forma unilateral o autónoma, sino que se encuentran asociadas a los profesores, a los planes y programas de estudio, a los proyectos de investigación y a las instituciones de posgrado; son factores que se interrelacionan e interactúan de forma positiva.
Resenha do livro - os donos do poder: formação do patronato brasileiro - de Raymundo Faoro
Authors: Sasso Gonzalez Marcelo
Published: June 2022

Em sua obra mais famosa, Raymundo Faoro expõe seu pensamento político a partir da análise da história portuguesa e da estruturação da monarquia no Brasil, traçando as raízes do patrimonialismo brasileiro e a formação do estamento burocrático. A trágica apropriação dos aparatos políticos e administrativos, bem como a utilização do poder público em benefício próprio evidenciam a necessidade de limites entre o poder público e o poder privado. Objetiva-se, com este breve trabalho, a análise crítica dos argumentos extraídos a partir do pensamento de Faoro, que se mostra essencial para interpretação e compreensão da atual realidade enfrentada pela sociedade brasileira sob o ponto de vista político e econômico.
Editorial
Authors: Nunes Júnior Vidal Serrano
Published: June 2022

Editorial
Acceso al agua potable, un derecho social con espíritu de derecho humano implícito y su configuración constitucional en el Perú
Authors: Trujillo Blas Edmundo
Published: June 2022

La presente investigación aborda el problema de la configuración del acceso al agua potable como un auténtico derecho humano, desde la perspectiva de su evolución y superando las tesis que abogan por su naturaleza de soft law, a partir de la decisión de la Corte IDH en el caso Comunidad Indígena Xákmok Kásek Vs. Paraguay (2010) concluye que hay abundantes razones para considerar su carácter vinculante respecto a los Estados.
ENSINO DE MATEMÁTICA NA REVISTA PRÁTICA DOCENTE: UMA ANÁLISE DE SIMILITUDE COM O USO DO IRAMUTEQ
Authors: Santos Carneiro Raylson dos , Beirigo Lopes Thiago , Seidel Luciano Dias Chiara Maria
Published: June 2022

Esse artigo apresenta os resultados de uma pesquisa cujo objetivo foi analisar as publicações da seção de Matemática e suas tecnologias da Revista Prática Docente. A pesquisa abordou o estado do conhecimento em relação à produção científica desse periódico, desde sua instituição em 2016 até o último número de 2021. Desenvolve-se um mapeamento da produção científica relacionada à prática docente em matemática, envolvendo tanto os métodos de ensino quando a formação inicial ou continuada de professores, sejam em práticas de ensino, relatos de experiência ou políticas públicas. Para o auxílio das análises, utilizou-se o programa IRaMuTeQ, que dentre suas funções fornece diversos tipos de análises de dados textuais, baseado na lexicografia das palavras. De acordo com os resultados, pode ser percebido que todas as Análises de Similitude realizadas a partir dos corpos textuais composto pelos resumos, objetivos, métodos e resultados indicados nos artigos relacionam a matemática com a formação de professores e com o ensino ou aprendizagem do estudante.
Budaya Kerja Berwawasan Cinta Lingkungan pada Pengikut Tarekat Qadiriyyah Wa Naqsyabandiyyah Kepulauan Meranti
Authors: Masduki Masduki , Hartono Toni
Published: June 2022

means take some effort to address the human spiritual disease. Therefore, it is important to restore (restoration) also farther more important is the emphasis on philosophical solution that focuses
Implementasi Pendidikan Karakter: Integrasi Lagu Melayu Sambas dalam Pembelajaran pada MIN Kabupaten Sambas
Authors: Putra Purniadi Adi
Published: June 2022

The lack of understanding and knowledge of children about the song and the type of song itself will have an impact on the character crisis, this is due to many who memorize the western-style romance songs compared to their own folk songs. The aim of learning Sambas Malay regional songs in the madrasa introduces directly to students and preserving Sambas Malay local culture especially at the elementary level children will sustain in the process of maintaining regional culture to stay alive, transfer and develop by means of learning processes contained in subjects and extracurricular regional art has implications for student character education. This study uses descriptive qualitative methods. The focus of this research is art teachers, students and madrasah principals with data sources from the MIN Sambas District of the Sambas Malay ethnic group. The results of this study are to strengthen the values of Sambas Malay character as a basic foundation in maintaining local wisdom, song art education as the basis of education in shaping the soul and personality of noble character (akhlakul karimah), the meaning of Sambas tandak song has religious value, bellale song ' having social values in collaboration, Sambas river songs flooded with environmental values, mak jage's rock songs having the value of peaceful love characters, and Allo 'Galing songs having social values and cooperation.
Hibriditas Dalam Pelestarian Pertunjukan Folklore Reyog Obyog di Kabupaten Ponorogo
Authors: Triani Feni Yuni , Yuwana Setya , Handayaningrum Warih
Published: June 2022

Penelitian ini membahas tentang hibriditas dalam pertunjukan folklore Reyog Obyog di Kabupaten Ponorogo. Lebih lanjut, penelitian ini ingin mengeksplorasi hibriditas dari bentuk pertunjukan, faktor-faktor yang memengaruhi, hibriditas kekinian dalam pertunjukan, dan negosiasi interdisiplin yang mampu mendukung pelestarian budaya folklore Reyog Obyog di Kabupaten Ponorogo. Penelitian ini menggunakan kualitatif studi kasus dengan pendekatan interdisiplin. Data primer dalam penelitian ini adalah pertunjukan folklore Reyog Obyog di Kabupaten Ponorogo, dengan menggunakan teknik pengumpulan data berupa (1) observasi terhadap pertunjukan folklore Reyog Obyog selama bulan Juli-Desember 2019 dan Januari-Februari 2020; (2) wawancara; dan (3) studi dokumentasi. Data yang dikumpulkan dianalisis secara deskriptif dengan sudut pandang hibriditas Homi K. Bhabha. Hasil penelitian menunjukkan bahwa pertunjukan folklore khas Ponorogo yaitu Reyog Obyog mengadaptasi dirinya dalam bentuk budaya hibrid yang mengarah ke kontemporer. Hal tersebut didasari atas strategi kebudayaan yang diperlukan oleh Reyog Obyog dalam eksistensinya di tengah arus global dengan hibriditas dilakukan pada pertunjukan dan unsur musikal, serta eksplorasi pelaku Reyog Obyog. Produksi eksperimental, menyandingkan Reyog Obyog dengan budaya lain menciptakan ruang untuk negosiasi ulang kebudayan Ponorogo dan Indonesia, redefinisi budaya, dan dekonstruksi stereotip lokalitas bahkan nasional. Di panggung global, Reyog Obyog memperoleh potensi untuk membawa pembebasan dari representasi dan label lokal. Lebih lanjut, estetika hibrida dapat digunakan sebagai strategi untuk potensi pariwisata dan menjadi pendukung dialog internasional, integrasi antar disiplin, dan transkulturalisme.
Analisis Ungkapan Tradisional Melayu Jambi: Kajian Hermeneutik
Authors: Warni Warni , Afria Rengki
Published: June 2022

AbstrakSebagai bagian dari kebudayaan, ungkapan tradisional menarik untuk dikaji. Ungkapan tradisional sebagai khazanah tak benda mengandung nilai, makna, dan seni berbahasa masyarakat melayu Jambi. Penelitian ini bertujuan untuk menginventarisasi, mendokumentasi, mendeskripsi, dan menganalisis bentuk, jenis-jenis, fungsi, dan makna Ungkapan Tradisional Melayu Jambi: Kajian Hermeneutik. Metode yang digunakan adalah metode deskriptif kualitatif. Sumber data berupa ungkapan tradisional melayu Jambi . Data penelitian ini adalah pepatah, petitih, kias, peribahasa dalam bahasa Melayu Jambi. Hasil penelitian disimpulkan bahwa beberapa data ungkapan tradisional melayu Jambi, baik berupa peribahasa, pepatah, maupun perumpamaan. Masyarakat Melayu Jambi pada umumnya dalam bertutur bersifat tidak terbuka, sehingga mereka menggunakan kiasan-kiasan untuk menyampaikan pesan dalam tuturan tersebut. Ungkapan tradisional Melayu Jambi mempunyai fungsi dalam kehidupan bersosial dimasyarakat. Fungsi tersebut adalah: Sebagai sarana edukasi masyarakat, Sebagai nasehat, dan Sebagai khazanah budaya tradisi lisan. Implikasi teoritis dalam penggunaan metode yang tepat dapat menghasilkan analisis data yang akurat. Secara praktis hasil kajian ini  dapat diimplikasikan sebagai  rujukan, dan pembanding dari penelitian-penelitian selanjutnya yang mendalami kajian hermeneutik.Kata Kunci: ungkapan, tradisional, melayu jambi, hermeneuticAbstractAs part of culture, traditional expressions are interesting to study. Traditional expression as a treasure not object contains the value, meaning, and language arts Jambi Malay community. This research aims to inventory, document, describe, and analyze the shape, type, function and meaning of expressions Traditional Malay Jambi: Study hermeneutic. The method used is a qualitative descriptive method. Data source Jambi Malay traditional form of expression. This research data is the maxim, proverb, analogy, saying in Malay Jambi. The results conclude that the number of traditional Malay Jambi expression data, in the form of proverbs, sayings, or parables. Jambi Malay community in general in the converse is not open, so they use metaphors to convey the message in speeches. Jambi Malay traditional expression has a function in the life of the community socialization. These functions are: As a means of public education, As advice, and As a cultural treasure of oral tradition. Theoretical implications in the use of appropriate methods can result in accurate data analysis. In practice, the results of this study can be implied as a reference, and a comparison of further studies that delve into hermeneutic studies.Keywords: expressions, traditional, Jambi Malay, hermeneutic