bluuebunny/crossref_metadata_2025 huggingface dataset:
Potential Prebiotic Effects of Artemisia capillaris-Derived Transglycosylated Product
Authors: Moon Heewon , Kang Keunsoo , Kim Misook
Published: October 2024

This study investigated the impact of a transglycosylated product (ACOD) catalyzed by Leuconostoc mesenteroides MKSR dextransucrase using sucrose as a glucosyl donor and both maltose and Artemisia capillaris as acceptors on gut microbiota through fecal fermentation. ACOD promoted the growth of probiotics such as Lactiplantibacillus plantarum, Lacticaseibacillus casei, Lacticaseibacillus rhamnosus GG, and Leuconostoc mesenteroides MKSR, while inhibiting the growth of pathogenic bacteria such as Escherichia coli, E. coli O157:H7, Enterococcus faecalis, Listeria monocytogenes, Staphylococcus aureus, Shigella flexneri, Streptococcus mutans, Pseudomonas aeruginosa, and Bacillus cereus during independent cultivation. Fecal fermentation for 24 h revealed that ACOD significantly increased the production of short-chain fatty acids (SCFAs) compared to the blank and fructoooligosaccharide (FOS) groups. Specifically, ACOD led to a 4.5-fold increase in acetic acid production compared to FOSs and a 3.3-fold increase in propionic acid production. Both the ACOD and FOS groups exhibited higher levels of butyric acid than the blank. Notably, ACOD significantly modulated the composition of the gut microbiota by increasing the relative abundances of Lactobacillus and decreasing Escherichia/Shigella and Salmonella. In contrast, FOSs remarkably promoted the growth of Salmonella. These findings suggest that ACOD is a potential candidate for prebiotics that improve the intestinal environment by being actively used by beneficial bacteria.
Triplication of the PCDH19 Gene as a Novel Disease Mechanism Leading to Epileptic Encephalopathy Resembling Loss-of-Function Pathogenic Variants
Authors: Gabaldón-Albero Alba , Smeyers Patricia , Hernández-Muela Sara , Roselló Mónica , Orellana Carmen , Monfort Sandra , Oltra Silvestre , Martínez Francisco
Published: October 2024

Background/Objectives: Developmental and epileptic encephalopathy 9 (DEE9) (MIM #300088) affects heterozygous females and males with somatic pathogenic variants, while male carriers with hemizygous PCDH19 pathogenic variants are clinically unaffected. There are hundreds of pathogenic single nucleotide variants in the PCDH19 gene reported in the literature, which lead to the loss of function of the PCDH19 protein. To date, no phenotypes associated with overexpression or copy number gains have been described in this gene. Methods and results: We present a female patient with a de novo triplication in the Xq21.3–q22.1 chromosomal region, which includes the PCDH19 gene, which implies an unbalanced dose gain. This patient displayed a phenotype of epileptic encephalopathy compatible with DEE9. By comparison, another male patient with a similar duplication showed mild developmental delay and autism but never developed epilepsy. Conclusions: Here, we propose the dose gain of PCDH19 as a new pathogenic mechanism that results in a phenotype similar to that found in patients with loss-of-function variants in PCDH19, when present in a heterozygous state.
Perioperative Rhabdomyolysis in Obese Individuals Undergoing Bariatric Surgery: Current Status
Authors: Duarte-Medrano Gilberto , Nuño-Lámbarri Natalia , Minutti-Palacios Marissa , Dominguez-Cherit Guillermo , Dominguez-Franco Analucia , La Via Luigi , Paternò Daniele Salvatore , Sorbello Massimiliano
Published: October 2024

One potential complication in bariatric surgery is rhabdomyolysis, which is a condition involving muscle tissue damage that can significantly impact a patient’s health. The causes of rhabdomyolysis can be broadly classified into two major categories: traumatic and non-traumatic. Early investigations into the development of intraoperative rhabdomyolysis in bariatric surgery identified the main risk factors as tissue compression—primarily affecting the lower extremities, gluteal muscles, and lumbar region—as well as prolonged periods of immobilization. Clinically, rhabdomyolysis is typically suspected when a patient presents with muscle pain, weakness, and potentially dark urine or even anuria. However, the most reliable biomarker for rhabdomyolysis is elevated serum creatine kinase levels. The primary goal in managing hydration is to correct intravascular volume depletion, with solutions such as Lactated Ringer’s or 0.9% saline being appropriate options for resuscitation. Perioperative diagnosis of rhabdomyolysis poses a significant challenge for anesthesiologists, requiring a high degree of clinical suspicion, particularly in bariatric patients. In this vulnerable population, prevention is crucial. The success of treatment depends on its early initiation; however, there are still significant limitations in the therapies available to prevent renal injury secondary to rhabdomyolysis.
Government Health Expenditure and Maternal Mortality: The Moderating Role of External Debt
Authors: Dinga Gildas Dohba , Mah Gisele , Mosikari Teboho
Published: October 2024

Background/Objectives: The impact of government health spending and external debt on maternal mortality has been the subject of ongoing theoretical and empirical discussions. However, this relationship has remained controversial with no perspective on the moderating role of external debt on the government’s health expenditure and maternal mortality link. This study examines the moderating effect of external debt on the government’s health expenditure and maternal mortality relation using data from 13 Southern African economies spanning from 2000 to 2022. Methods: We employed the augmented mean group, the dynamic common correlation effect mean group, and the Driscoll–Kraay and Granger causality techniques to attain the study’s objective. Results: The outcome revealed that government health expenditure and external debt reduce maternal mortality in the Southern African Development Community (SADC) region. Equally, the magnitude of government health spending is moderated by external debt. The results revealed a bidirectional relation amidst maternal mortality and government health expenditure, and maternal mortality and external debt. Conclusions: The study recommends that policymakers within the SADC zone should avoid austerity measures and encourage expansionary measures in terms of spending, and the contraction of debt for capital investment in the health sector. This will enhance the delivery of health services within the zone and equally reduce the rate of maternal mortality that is still a major health concern within the sub-region.
Literacy in the Scope of Radiation Protection for Healthcare Professionals Exposed to Ionizing Radiation: A Systematic Review
Authors: Rodrigues Belinda V. , Lopes Pedro C. , Mello-Moura Anna C. , Flores-Fraile Javier , Veiga Nelio
Published: October 2024

Background: The use of radiation is important in different medical procedures, and to ensure a high level of good medical practice, radiation protection (RP) should be seen as a very important subject. This review shows information about the knowledge in the scope of radiation protection among healthcare professionals exposed to ionizing radiation. There are not many studies that evaluate the radiation exposure of healthcare professionals. Methods: A systematic search was performed, using PRISMA guidelines, in Pubmed and Scopus databases and manually to identify relevant articles to answer the PICOS question, “Is there an adequate level of literacy in the scope of radiation protection among healthcare professionals exposed to ionizing radiation?”. This systematic review included cross-sectional studies with the following inclusion criteria: (i) in Portuguese, Spanish, or English; (ii) about literacy in the scope of radiation protection; (iii) published between 2017 and 2024; and (iv) participants must be dentists, radiographers, doctors, and nurses. The JBI critical assessment tool was used to assess the risk of bias. Results: The search identified 566 potentially relevant references, which, after applying inclusion/exclusion criteria, resulted in 12 articles. Studies found that the overall knowledge of these healthcare workers was unsatisfactory, and a lack of knowledge in radiation protection negatively affects health services’ quality. Training is essential and must emphasize how radiation exposure can be minimized, safeguarding health professionals’ trust and sense of security. Results showed that more years of experience make workers more attentive to protection measures, suggesting that training strategies focused on basic radiological risks and radiation safety are needed. Conclusions: Key findings recommend implementing a standardized national training program on the basic principles and safety of ionizing radiation for all healthcare professionals.
Impact of Multi-Professional Intervention on Health-Related Physical Fitness and Biomarkers in Overweight COVID-19 Survivors for 8 and 16 Weeks: A Non-Randomized Clinical Trial
Authors: Silva-Lalucci Marielle Priscila de Paula , Marques Déborah Cristina de Souza , Ryal Joed Jacinto , Marques Marilene Ghiraldi de Souza , Perli Victor Augusto Santos , Sordi Ana Flávia , de Moraes Solange Marta Franzoi , Valdés-Badilla Pablo , Andreato Leonardo Vidal , Branco Braulio Henrique Magnani
Published: October 2024

Background/objectives: Considering the diverse symptomatology of COVID-19—ranging from mild to severe cases—multi-professional interventions are crucial for enhancing physical recovery, nutritional status, and mental health outcomes in affected patients. Thus, this study aimed to investigate the effects of such an intervention on health-related physical fitness and biomarkers in overweight COVID-19 survivors with varying degrees of symptom severity after 8 weeks and 16 weeks. Methods: This non-randomized clinical trial included 59 overweight COVID-19 survivors (32 males and 27 females) divided into three groups: mild (n = 31), moderate (n = 13), and severe/critical (n = 15). The participants underwent a multi-professional program and were assessed for anthropometric and body composition (primary outcome), as well as physical fitness and biochemical markers (secondary outcome) 8 and 16 weeks before the intervention. Results: After 8 weeks, time effects were observed for the maximum isometric handgrip strength (p < 0.001), maximum isometric lumbar-traction strength (p = 0.01), flexibility (p < 0.001), abdominal strength–endurance (p < 0.001), the sit-and-stand test (p < 0.001), maximum oxygen consumption (p < 0.001), and distance covered in the 6 min walk test (p < 0.001). Additionally, time effects were also observed for fat mass (p = 0.03), body fat percentage (p = 0.02), abdominal circumference (p = 0.01), total cholesterol (p < 0.001), low-density lipoproteins (p < 0.001), and glycated hemoglobin (p < 0.001), with lower values after multi-professional interventions. After 16 weeks, the systolic and diastolic blood pressure showed significant reductions independently of the intervention group (p < 0.001). Conclusion: These findings suggest that multi-professional interventions can provide substantial benefits for post-COVID-19 patients, regardless of the severity of their initial symptoms.
Prevalence of Depressive Symptoms in a Predominantly Hispanic/Latinx South Texas Community in the Aftermath of the COVID-19 Pandemic
Authors: Huang Yuxia , Hu Zhiyong , Guerrero Ana , Brennan Emily , Gonzales Xavier F.
Published: October 2024

Objective: COVID-19 has a lasting impact on mental health, particularly within the Hispanic/Latinx communities. This paper empirically investigates the post-COVID-19 presence and severities of depression, one of the most common mental health disorders, among adults in a predominantly U.S.-born Hispanic/Latinx community in South Texas composed primarily of Mexican Americans. Methods: Multiple statistic regression models were applied to data from 515 adults in Nueces County who completed all questions in a survey from convenience sampling between June 2022 and May 2023. Depression was assessed using both standard PHQ-2 and PHQ-9 measurements. Results: Of the 515 participants, 377 (64.5%) were Hispanic, and 441 (85.6%) had a high school education or higher, reflecting the county’s demographics. About half of the participants (47%) reported mild/moderate to severe depression. The regression model estimation results reveal that female participants, those not in full-time employment, and individuals with disabilities were more likely to feel depressed after COVID-19. Middle-aged adults demonstrated greater resilience to depression compared to other age groups. Notably, non-Hispanic participants in the study reported higher levels of depression compared to their Hispanic counterparts. Additionally, COVID-19-related experiences, such as testing positive for the virus, being hospitalized, or having a history of depression before COVID-19, were associated with higher levels of reported depression. Conclusions: COVID-19 has significantly impacted the mental health of this predominantly U.S.-born Hispanic/Latinx community. These findings can assist healthcare providers and policymakers in developing targeted strategies to tailor interventions aimed at enhancing mental health well-being, reducing disparities, and fostering overall improvement within the Hispanic/Latinx community.
Upfront Thoracic Magnetic Resonance Imaging for the Evaluation of Thymic Lesions to Reduce Non-Therapeutic Diagnostic Thymectomy: A Narrative Review
Authors: Le Khang Duy Ricky , Wang Annie Jiao , Haycock Shasha , Fink Kaylah , Lee Su Jin
Published: October 2024

Background: Thymic pathologies represent the most common lesions of the anterior mediastinum. They may be classified as malignant or benign. Current diagnostic pathways recommend an initial assessment with computed tomography (CT) imaging to delineate potentially malignant thymic lesions. Despite this, high rates of non-therapeutic thymectomy continue to be observed. This carries with it significant anaesthetic, operative, and post-operative risks, in addition to healthcare costs. Consequently, there is a growing interest in magnetic resonance imaging (MRI) as a primary diagnostic modality for lesions of the anterior mediastinum. This narrative review outlines the current approaches to the evaluation of thymic lesions, with a discussion of the strengths and limitations of CT and MRI imaging modalities. It also evaluates the current discourse on the use of upfront MRI for thymic and anterior mediastinal lesion assessment. Methods: A narrative review was performed following a search on the Medline database. Articles that were evaluated had explored the role of MRI on the evaluation of thymic and anterior mediastinal lesions. Results: Current work-up for thymic and anterior mediastinal lesions are highly variable and centre around the use of CT. Upfront MRI demonstrates a similar accuracy to CT for various thymic and anterior mediastinal pathologies; however, the efforts to integrate this approach into routine practice remain in their infancy, with no standardised guidelines that exist. Conclusions: This narrative review demonstrates that there is a paucity of evidence relating to the sensitivity and specificity of MRI compared to CT for thymic lesion analysis and their subsequent relationship with non-therapeutic thymectomy. Future prospective trials to assess the role of MRI in thymic lesion determination are required to understand whether MRI can more accurately characterise these lesions to reduce non-therapeutic thymectomy. Additionally, further research efforts are required to characterise best-practice methods for integrating MRI into diagnostic pathways for these lesions in a cost-effective and resource-conscious manner.
Extending Raspberry Shelf Life and Maintaining Postharvest Quality with CO2 Atmospheres
Authors: Islam Mohd Rezaul , Mitcham Elizabeth
Published: October 2024

Raspberry (Rubus idaeus L.) fruit are known for their extremely short shelf life. Decay, leakiness, and loss of firmness are the most common limiting factors contributing to their short storage life. However, storage in elevated CO2 and reduced O2 atmospheres can delay senescence in fruit by reducing softening, respiration and ethylene production rates, and pathogen growth. In this study, raspberries were exposed to four different CO2 atmospheres—15 kPa CO2 and 6 kPa O2 (15 kPa); 8 kPa CO2 and 13 kPa O2 (8 kPa); 5 kPa CO2 and 16 kPa O2 (5 kPa); or 0.03 kPa CO2 and 21 kPa O2 (0.03 kPa)—and were evaluated for their postharvest quality periodically during two weeks of storage in 2020 and 2021. Raspberry fruits kept in a 15 kPa CO2 atmosphere followed by 8 kPa CO2 had higher firmness, brighter red color, and the least fungal decay or leakiness. In all atmospheres, the total anthocyanin content increased over time, although the rate of increase was slowed by high CO2. The raspberries’ visual attributes deteriorated over time in all atmospheres, but high CO2 atmospheres slowed the rate of deterioration. After five days, the quality of air-stored raspberries was significantly degraded, while the raspberries stored in elevated CO2 maintained good quality for up to ten days.
Endophyte Bacillus vallismortis BL01 to Control Fungal and Bacterial Phytopathogens of Tomato (Solanum lycopersicum L.) Plants
Authors: Chebotar Vladimir K. , Gancheva Maria S. , Chizhevskaya Elena P. , Erofeeva Anastasia V. , Khiutti Alexander V. , Lazarev Alexander M. , Zhang Xiuhai , Xue Jing , Yang Chunhong , Tikhonovich Igor A.
Published: October 2024

Some strains of Bacillus vallismortis have been reported to be efficient biocontrol agents against tomato pathogens. The aim of our study was to assess the biocontrol ability of the endophytic strain BL01 Bacillus vallismortis through in vitro and field trials, as well as to verify its plant colonization ability and analyze the bacterial genome in order to find genes responsible for the biocontrol activity. We demonstrated in a gnotobiotic system and by confocal laser microscopy that the endophytic strain BL01 was able to colonize the endosphere and rhizosphere of tomato, winter wheat and oilseed rape. In vitro experiments demonstrated the inhibition activity of BL01 against a wide range of phytopathogenic fungi and bacteria. BL01 showed biological efficacy in two-year field experiments with tomato plants against black bacterial spotting by 40–70.8% and against late blight by 47.1% and increased tomato harvest by 24.9% or 10.9 tons per hectare compared to the control. Genome analysis revealed the presence of genes that are responsible for the synthesis of biologically active secondary metabolites, which could be responsible for the biocontrol action. Strain BL01 B. vallismortis can be considered an effective biocontrol agent to control both fungal and bacterial diseases in tomato plants.
Massive Education in Prison Health in Brazil: A Look Beyond the Walls
Authors: Valentim Janaina , Dias-Trindade Sara , Dias Aline , Caitano Alexandre , Nunes Laysa , Romão Manoel , Fernandes Felipe , Veras Nícolas , Medeiros Kelson , Melo Ronaldo , Bezerra Edneide , Quintas-Mendes Antonio , Bonfim Marilyn , Ferla Alcindo , Ceccim Ricardo , Valentim Ricardo
Published: October 2024

Equal access to health initiatives and services under the principles of universal and comprehensive care remains a challenge in Brazil. The realization of public health policies is further intricate when one examines the health situation of people deprived of liberty. This study showcases the “Prison System: Beyond the Walls” educational pathway, available on the Virtual Learning Environment of the Brazilian National Health System (AVASUS). The action research methodological strategy guided the pathway development, emphasizing dialogic learning. The goal was to address the need for massive training on the topic of prison health, with the model focusing on engagement through spontaneous, non-mandatory participation in the pathway courses. The pathway comprised four modules, whose educational offerings were based on the self-learning model. Students were free to choose which courses to take and in what order, as there was no prerequisite for participating in modules. Hence, students could either take all the courses or only those with which they identify their learning needs, regardless of work demands or personal interests. Structuring the pathway through action research facilitated a massive, cohesive, and continuous training process. This approach expanded knowledge and established meaningful relationships among the related topics and the key players involved: health professionals, prison officers, and people deprived of liberty. Notably, the pathway courses have surpassed the 50,000-enrollment mark, spanning all five regions of Brazil. In this context, this article presents and discusses the development of the “Prison System: Beyond the Walls” pathway, emphasizing the massive improvement of health within Brazil’s prison system and highlighting the results achieved.
Evaluation of Red Blood Cell Biochemical Markers and Coagulation Profiles Following Cell Salvage in Cardiac Surgery: A Systematic Review and Meta-Analysis
Authors: Cáceres-Matos Rocío , Luque-Oliveros Manuel , Pabón-Carrasco Manuel
Published: October 2024

Background: Individuals undergoing cardiac surgery face an increased risk of bleeding, as well as alterations in biochemical and coagulation patterns. Therefore, assessing the effectiveness of systems such as Cell Salvage is necessary to prevent potential surgical complications. Objective: To evaluate the efficacy of Cell Salvage in relation to the biochemical parameters of the red blood series and coagulation, as well as the risk of hemorrhage. Methods: A systematic review, accompanied by a meta-analysis, was executed via an extensive literature exploration encompassing Medline, CINAHL, Scopus, Web of Science, and the Cochrane Library. The inclusion criteria comprised studies in English or Spanish, without year restrictions, conducted in adults and with a randomized controlled trial design. Results: Twenty-six studies were included in the systematic review, involving a total of 2850 patients (experimental group = 1415; control group = 1435). Cell Salvage did not demonstrate superior outcomes compared to allogeneic transfusions in the management of post-surgical hemorrhage, as well as in total blood loss, platelet count, fresh frozen plasma, and fibrinogen. However, Cell Salvage showed a greater effectiveness for hemoglobin (moderate evidence), hematocrit (low evidence), post intervention D-dimer (low evidence), and some coagulation-related parameters (low evidence) compared to allogeneic transfusions. Finally, better results were found in the control group for INR parameters. Conclusions: The use of the Cell Salvage system holds high potential to improve the postoperative levels of biochemical and coagulation parameters. However, the results do not provide definitive evidence regarding its effectiveness for hemorrhage control, platelet count, fresh frozen plasma, and fibrinogen. Therefore, it is recommended to increase the number of studies to assess the impact of the Cell Salvage system on improvements in the red blood cell count and patient coagulation patterns. In addition, protocols should be homogenized, and variables such as the sex of the participants should be taken into account.
Osteoblast Response to Widely Ranged Texturing Conditions Obtained through High Power Laser Beams on Ti Surfaces
Authors: Ruffinatti Federico Alessandro , Genova Tullio , Roato Ilaria , Perin Martina , Chinigò Giorgia , Pedraza Riccardo , Della Bella Olivio , Motta Francesca , Aimo Boot Elisa , D’Angelo Domenico , Gatti Giorgio , Scarpellino Giorgia , Munaron Luca , Mussano Federico
Published: October 2024

Titanium and titanium alloys are the prevailing dental implant materials owing to their favorable mechanical properties and biocompatibility, but how roughness dictates the biological response is still a matter of debate. In this study, laser texturing was used to generate eight paradigmatic roughened surfaces, with the aim of studying the early biological response elicited on MC3T3-E1 pre-osteoblasts. Prior to cell tests, the samples underwent SEM analysis, optical profilometry, protein adsorption assay, and optical contact angle measurement with water and diiodomethane to determine surface free energy. While all the specimens proved to be biocompatible, supporting similar cell viability at 1, 2, and 3 days, surface roughness could impact significantly on cell adhesion. Factorial analysis and linear regression showed, in a robust and unprecedented way, that an isotropic distribution of deep and closely spaced valleys provides the best condition for cell adhesion, to which both protein adsorption and surface free energy were highly correlated. Overall, here the authors provide, for the first time, a thorough investigation of the relationship between roughness parameters and osteoblast adhesion that may be applied to design and produce new tailored interfaces for implant materials.
A Study on the Design of Embedded Visual Image Teaching Aids to Assist Young Children’s Cognitive and Fine Motor Development
Authors: Lo Hua-Chen , Wang Tzu-Hua
Published: October 2024

Visual development in infancy is crucial for establishing neural connections and enhancing the growth of the visual center. Adequate visual stimulation supports cognitive learning, helping children integrate images, colors, and shapes. This research examines the design and use of a visual image teaching aid to guide children in exploring image cognition and developing fine motor skills. This study involved 70 kindergarten teachers who participated in a questionnaire survey about 60 children aged from 5 to 6 years old. The results show that visual graphic aids effectively promoted coordination, control, and the integration of visual and fine motor skills in children. Furthermore, these aids supported the development of spatial and environmental relationships through hands-on activities.
A Study of Free Surface Agitation in a Shipyard Using Numerical Modeling
Authors: Herrera Israel E. , Galván Arturo , Moreno-Martínez Jatziri Y. , Gamiño Edith A.
Published: October 2024

In recent years, the Port of Topolobampo, Sinaloa, Mexico, has experienced unusual free sea surface elevations, particularly during the months of November and December, affecting the shipyard areas, service docks, and berthing locations. This study focuses on analyzing the oscillatory behavior of free surface elevations in shipyard regions. A hydrodynamic model was employed to simulate the circulation and sea surface agitation, aiming to quantify the elevation magnitudes based on oceanographic and meteorological data from November of the preceding year. A 30-day numerical simulation was conducted, revealing the velocity fields associated with coastal currents and tides during November, as well as the interaction between incident waves and wave transformations due to protective structures. The results demonstrated accurate behavior in 95% of the simulation period, while anomalous elevations exceeding those specified in the design and operational guidelines of the Port of Topolobampo were observed during the final five days of the simulation. An ANOVA test was performed between the surface elevation and vertically integrated velocity to assess whether the deviations in the last five days were statistically significant compared to the rest of the simulation period. With a P-value of less than 0.05, the null hypothesis of no difference was rejected, confirming a significant variation. These findings suggest that the extreme values recorded should be considered for the potential redesign of shipyard infrastructure.
Optimized Trajectory Tracking for ROVs Using DNN + ENMPC Strategy
Authors: Yang Guanghao , Liu Weidong , Li Le , Xu Jingming , Guo Liwei , Zhang Kang
Published: October 2024

This study introduces an innovative double closed-loop 3D trajectory tracking approach, integrating deep neural networks (DNN) with event-triggered nonlinear model predictive control (ENMPC), specifically designed for remotely operated vehicles (ROVs) under external disturbance conditions. In contrast to single-loop model predictive control, the proposed double closed-loop control system operates in two distinct phases: (1) The outer loop controller uses a DNN controller to replace the LMPC controller, overcoming the uncertainties in the kinematic model while reducing the computational burden. (2) The inner loop velocity controller is designed using a nonlinear model predictive control (NMPC) algorithm with its closed-loop stability proven. A DNN + ENMPC 3D trajectory tracking method is proposed, integrating a velocity threshold-triggered mechanism into the inner-loop NMPC controller to reduce computational iterations while sacrificing only a small amount of tracking control performance. Finally, simulation results indicate that compared with the ENMPC algorithm, NMPC + ENMPC can better track the desired trajectory, reduce thruster oscillations, and further minimize the computational load.
Fundamental Understanding of Marine Applications of Molten Salt Reactors: Progress, Case Studies, and Safety
Authors: Park Seongchul , Kim Sanghwan , Bari Gazi A. K. M. Rafiqul , Jeong Jae-Ho
Published: October 2024

Marine sources contribute approximately 2% of global energy-related CO₂ emissions, with the shipping industry accounting for 87% of this total, making it the fifth-largest emitter globally. Environmental regulations by the International Maritime Organization (IMO), such as the MARPOL (International Convention for the Prevention of Pollution from Ships) treaty, have driven the exploration of alternative green energy solutions, including nuclear-powered ships. These ships offer advantages like long operational periods without refueling and increased cargo space, with around 200 reactors already in use on naval vessels worldwide. Among advanced reactor concepts, the molten salt reactor (MSR) is particularly suited for marine applications due to its inherent safety features, compact design, high energy density, and potential to mitigate nuclear waste and proliferation concerns. However, MSR systems face significant challenges, including tritium production, corrosion issues, and complex behavior of volatile fission products. Understanding the impact of marine-induced motion on the thermal–hydraulic behavior of MSRs is crucial, as it can lead to transient design basis accident scenarios. Furthermore, the adoption of MSR technology in the shipping industry requires overcoming regulatory hurdles and achieving global consensus on safety and environmental standards. This review assesses the current progress, challenges, and technological readiness of MSRs for marine applications, highlighting future research directions. The overall technology readiness level (TRL) of MSRs is currently at 3. Achieving TRL 6 is essential for progress, with individual components needing TRLs of 4–8 for a demonstration reactor. Community Readiness Levels (CRLs) must also be addressed, focusing on public acceptance, safety, sustainability, and alignment with decarbonization goals.
Optimization of Connection Parameters of Self-Adaptive Modular Floating Wind Farms
Authors: Zhang Yuming , Li Da , Liu Haixiao
Published: October 2024

Connection parameters are the key factors influencing the responses of modular floating structures; due to the complexity of structural response properties, the assessment and optimization of connection parameters are still vital issues in designing modular floating structures. In the present work, for a novel structural configuration of self-adaptive modular floating wind farms based on existing works from the case of a mobile offshore base, a quantified approach for the assessment of connection parameters is established based on frequency domain numerical analysis taking into account both the economic effects and generalized performance. Based on the quantified assessment, an optimization process is carried out, to obtain a connection parameter combination. From the optimized connection parameters, it can be found that the most appropriate tri-axial stiffness according to present studies is in the magnitude from 1 × 106 to 7 × 107 N/m, and the damping ratio is close to 1.0 for most connection structures. By contrast with feasible uniform connection parameters, the optimization methodology is confirmed to be able to reduce both connection parameters and responses. Then, a time domain approach for the calculation of motions of interconnected modular floating structures taking into account geometry nonlinearity is proposed and obtained in good accordance with the frequency domain results, and the effectiveness of both the frequency domain and time domain is validated.
Myocarditis: Differences in Clinical Expression between Patients with ST-Segment Elevation in Electrocardiogram vs. Patients without ST-Segment Elevation
Authors: Ramantauskaitė Grytė , Okeke Kingsley A. , Mizarienė Vaida
Published: October 2024

Background/Objectives: In cases of myocarditis, electrocardiograms (ECGs) may suggest a pattern of ST-segment elevation myocardial infarction (STEMI) or non-ST-segment elevation myocardial infarction (NSTEMI). NSTEMI patterns are less frequent in myocarditis cases, but it remains unclear if the presence of ST-segment elevation in myocarditis cases is related to a more severe condition and more damage in the myocardium. Methods: This is a retrospective study involving 38 patients admitted to hospital with myocarditis. Patients were divided into two groups: patients with ST-segment elevation (STE) patterns in the ECG (25), and patients without ST-segment elevation (non-STE) patterns (13). The data compared included results from epidemiological, laboratory, and instrumental tests. Data were analysed using IBM SPSS Statistics v26.0. A p value of <0.05 was established as the threshold for statistical significance. Results: C-reactive protein (CRP) levels were higher in the STE group (103.40 ± 82.04 mg/L vs. 43.54 ± 61.93 mg/L, p = 0.017). The left ventricle ejection fraction (LVEF) was significantly higher in the non-STE pattern group (49.71 ± 4.14 vs. 56.58 ± 3.99, p < 0.001). A lower LVEF correlates with higher TnI levels (r= −0.353, p = 0.032) and higher CRP levels (r = −0.554, p < 0.001). Lower left ventricle (LV) strain correlates with higher levels of Troponin I (TnI) (r = −0.641, p = 0.013). Conclusions: LVEFs in the STE group were lower compared to those in the non-STE pattern group. STE pattern was associated with higher CRP levels. Higher TnI levels in cases of myocarditis were associated with lower LV strain and lower LVEF; higher CRP levels also correlated with lower LVEF. Based on a 6-month echocardiographic follow-up, the prognosis of myocarditis was favourable.
Do Firms’ Characteristics Influence Their IT Strategies? A Study on the Driving Force behind Firms’ Decisions to Appoint IT Expertise
Authors: Khallaf Ashraf , Samet Anis , Efendi Jap
Published: October 2024

The demand for information technology expertise has grown rapidly in the last few decades, signaling firms’ commitment to integrating IT into core business strategies. Understanding the conditions under which firms appoint a chief information officer (CIO) can provide valuable insights into the evolving role of IT in corporate governance. This study addresses a crucial gap in the literature by exploring the determinants of a firm’s decision to hire a CIO at the top management level. The study identifies several factors that influence a firm’s decision to appoint a CIO, including the firm’s size, its level of innovation, and its prior performance. The study examines these assertions by comparing the characteristics of firms that appoint a CIO at the top management level with those of similar firms in their industries that do not have a CIO position prior to the appointment. A logistic regression model that considers CIO firms and their matched firms indicates that firms that have larger capital expenditures, higher market value, or have experienced loss are more likely to hire a new CIO. Our study provides empirical evidence on why certain firms prioritize IT leadership at the executive level.
The Role of Green Infrastructure in Providing Urban Ecosystem Services: Insights from a Bibliometric Perspective
Authors: Sokolova Milena V. , Fath Brian D. , Grande Umberto , Buonocore Elvira , Franzese Pier Paolo
Published: October 2024

Urban ecosystems, and the services they provide, are a key focus of the United Nations 2030 Agenda for Sustainable Development, specifically SDG 11, which emphasizes making cities inclusive, safe, resilient, and sustainable. Green infrastructure (GI) is crucial in enhancing citizens’ quality of life and achieving this goal and it can be defined as a strategically planned network of natural and semi-natural areas designed to deliver a range of ecosystem services (ESs). These infrastructures improve ecosystem functioning, protect biodiversity, promote health, support sustainable land and water management, and boost the local green economy. This paper explores the scientific literature on GI and their ESs in cities using bibliometric science. By combining the keywords “Green Infrastructures”, “Ecosystem Services”, and “Cities” with VOSviewer software (1.6.20 version), we analyzed trends over time. Results show growing attention to these topics, emphasizing human well-being, urban resilience, and sustainability. The study also highlights that focusing exclusively on either “Green Infrastructure in Cities” or “Ecosystem Services in Cities” leads to fragmented insights. A more integrated examination of these three domains offers a holistic view and underscores the importance of considering ecosystem disservices. The study further identifies key research directions, including the need for a comprehensive evaluation of diverse GI types, especially those that are under-researched, such as green roofs, sports areas, and wetlands, and the underexplored role of cultural ecosystem services. Additionally, future research should consider both the benefits and disservices of GI to support better urban planning decisions. Finally, integrating biophysical, social, and economic values of ESs is critical for providing more holistic insights and enhancing sustainable urban development. The novelty of this paper lies in its integrated, holistic approach to examining GI and ESs in urban areas, with a focus on ecosystem disservices, insufficient attention to specific GI types, and the role of cultural ecosystem services—each contributing to the creation of more resilient and sustainable cities.
Assessment of Ventilation Potential and Construction of Wind Corridors in Chengdu City Based on Multi-Source Data and Multi-Model Analysis
Authors: Xia Xiaojiang , Jian Ling , Ouyang Kaiji , Liu Xiuying , Liang Xuewen , Zhang Yang , Li Bojia
Published: October 2024

The establishment of urban ventilation corridors (UVCs) aims to mitigate the urban heat island effect. While most studies focus on the construction and assessment of the environmental benefit of UVCs, they often overlook the analysis of UVCs’ topological features. This research integrates multi-source data including 3D urban buildings, historical meteorological observations, high-resolution remote sensing, and land use planning, combined with multiple models, including geographic information system spatial analysis, circuit theory, and complex networks. Based on an assessment of urban ventilation potential, the circuit model was applied to extract UVCs aligned with the prevailing wind direction for both summer and winter seasons. Complex network modeling was employed to analyze the topological features of the ventilation network. From the analytical results, a multi-level wind corridor system for Chengdu was quantitatively developed. The results indicate that the city’s overall ventilation resistance is high, with notable spatial clustering, and the southeastern region faces substantial ventilation obstructions. A total of 143 critical ventilation nodes were identified, with the number of air inlets and outlets in summer being significantly fewer than in winter. However, the cooling effect of ventilation corridors in the prevailing summer wind direction is superior to that in winter. The ventilation network comprises 16 communities with distinct ventilation characteristics, exhibiting moderate connectivity, lacking small-world properties, and showing congestion and instability.
Enhanced Diffusion and Non-Gaussian Displacements of Colloids in Quasi-2D Suspensions of Motile Bacteria
Authors: Chen Xiao , Yan Yaner
Published: October 2024

In the real world, active agents interact with surrounding passive objects, thus introducing additional degrees of complexity. The relative contributions of far-field hydrodynamic and near-field contact interactions to the anomalous diffusion of passive particles in suspensions of active swimmers remain a subject of ongoing debate. We constructed a quasi-two-dimensional microswimmer–colloid mixed system by taking advantage of Serratia marcescens’ tendency to become trapped at the air–water interface to investigate the origins of the enhanced diffusion and non-Gaussianity of the displacement distributions of passive colloidal tracers. Our findings reveal that the diffusion behavior of colloidal particles exhibits a strong dependence on bacterial density. At moderate densities, the collective dynamics of bacteria dominate the diffusion of tracer particles. In dilute bacterial suspensions, although there are multiple dynamic types present, near-field contact interactions such as collisions play a major role in the enhancement of colloidal transport and the emergence of non-Gaussian displacement distributions characterized by heavy exponential tails in short times. Despite the distinct types of microorganisms and their diverse self-propulsion mechanisms, a generality in the diffusion behavior of passive colloids and their underlying dynamics is observed.
Numerical Simulation of Rubber Concrete Considering Fatigue Damage Accumulation of Cohesive Zone Model
Authors: Liu Cai , Li Houmin , Min Kai , Li Wenchao , Wu Keyang
Published: October 2024

Rubber concrete (RC) has been used in fatigue-resistant components due to its durability, yet the numerical simulation of its fatigue properties remains in its early stages. This study proposes a cohesive zone model (CZM) that accounts for the accumulation of fatigue damage at the mesoscale to investigate the fatigue performance of RC. The model integrates static and fatigue damage in the CZM, effectively capturing damage caused by fatigue loading. Validation was conducted using experimental data from the existing literature. Based on this validation, four concrete beams with varying rubber replacement rates (0%, 5%, 10%, and 15%) were tested. The CZM was employed to describe the mechanical behavior of the interface transition zones (ITZs) and the mortar interior, which were simulated and analyzed under different stress levels. The results demonstrate that the model accurately simulates crack propagation paths, interface damage evolution, and the fatigue life of RC beams under fatigue loading. A functional relationship between fatigue life and stress level was established for various rubber replacement rates. This study provides a reference model for numerical simulations of RC under fatigue loading conditions and introduces new approaches for analyzing the fatigue performance of other materials.
Implementing PSO-LSTM-GRU Hybrid Neural Networks for Enhanced Control and Energy Efficiency of Excavator Cylinder Displacement
Authors: Nguyen Van-Hien , Do Tri Cuong , Ahn Kyoung-Kwan
Published: October 2024

In recent years, increasing attention has been given to reducing energy consumption in hydraulic excavators, resulting in extensive research in this field. One promising solution has been the integration of hydrostatic transmission (HST) and hydraulic pump/motor (HPM) configurations in parallel systems. However, these systems face challenges such as noise, throttling losses, and leakage, which can negatively impact both tracking accuracy and energy efficiency. To address these issues, this paper introduces an intelligent real-time prediction framework for system positioning, incorporating particle swarm optimization (PSO), long short-term memory (LSTM), a gated recurrent unit (GRU), and proportional–integral–derivative (PID) control. The process begins by analyzing real-time system data using Pearson correlation to identify hyperparameters with medium to strong correlations to the positioning parameters. These selected hyperparameters are then used as inputs for forecasting models. Independent LSTM and GRU models are subsequently developed to predict the system’s position, with PSO optimizing four key hyperparameters of these models. In the final stage, the PSO-optimized LSTM-GRU models are employed to perform real-time intelligent predictions of motion trajectories within the system. Simulation and experimental results show that the model achieves a prediction deviation of less than 3 mm, ensuring precise real-time predictions and providing reliable data for system operators. Compared to traditional PID and LSTM-GRU-PID controllers, the proposed controller demonstrated superior tracking accuracy while also reducing energy consumption, achieving energy savings of up to 10.89% and 2.82% in experimental tests, respectively.
Research on Surface Defect Positioning Method of Air Rudder Based on Camera Mapping Model
Authors: Yang Zeqing , Xu Kangni , Zhang Mingxuan , Chen Yingshu , Hu Ning , Zhang Yi , Jin Yi , Lv Yali
Published: October 2024

(1) Background: Air rudders are used to control the flight attitude of aircraft, and their surface quality directly affects flight accuracy and safety. (2) Method: Traditional positioning methods can only obtain defect location information at the image level but cannot determine the defect’s physical surface position on the air rudder, which lacks guidance for subsequent defect repair. We propose a defect physical surface positioning method based on a camera mapping model. (3) Results: Repeated positioning experiments were conducted on three typical surface defects of the air rudder, with a maximum absolute error of 0.53 mm and a maximum uncertainty of 0.26 mm. Through hardware systems and software development, the real-time positioning function for surface defects on the air rudder was realized, with the maximum axial positioning error for real-time defect positioning being 0.38 mm. (4) Conclusions: The proposed defect positioning method meets the required accuracy, providing a basis for surface defect repair in the air rudder manufacturing process. It also offers a new approach for surface defect positioning in similar products, with engineering application value.