bluuebunny/crossref_metadata_2025 huggingface dataset:
Carbody vibrations of high-speed train caused by dynamic unbalance of underframe suspended equipment
Authors: Wang Qunsheng , Zeng Jing , Wei Lai , Zhu Bin
Published: December 2018

The effect of dynamic unbalance of the underframe suspended rotational equipment on the flexible vibrations of the carbody has become a major concern for high-speed trains. It is known from the field tests that the dynamic unbalance has a significant influence on carbody vibrations, especially the local flexible vibration, which leads to a decrease in the passenger ride comfort and may even cause structural damage to the carbody. A vertical mathematic model considering the carbody flexibility and the underframe suspended equipment is first set up, and then a three-dimensional dynamic model for a rigid–flexible coupled vehicle system is established. The effect mechanism of the dynamic unbalance on carbody flexible vibration is extensively studied, and the efficient measures to reduce the carbody flexible vibrations are proposed. The theoretical and simulation models are verified by comparing with a field test conducted on a newly designed high-speed railway. The results show that decreasing the unbalanced mass of the rotational equipment can reduce the carbody vibrations. Moreover, the use of elastic suspension for the underframe equipment can isolate the vibration transmission to the carbody. Both the theory of dynamic vibration absorber and dynamic unbalance should be considered to optimize reasonable suspension parameters, especially the suspension location and the suspension frequency.
The context of litigation in evaluating physical and psychological outcomes from pain management programmes
Authors: Twiddy Hannah , Brown Richard J , Waheed Hasan
Published: December 2018

Objectives:

There has been extensive research in evaluating chronic pain in the context of litigation while considering the implications that it can have on healthcare outcomes and rehabilitation progress. The aim of this article is to present retrospective observational data about the levels of disability and distress reported by patients with ongoing litigation at the start and following a UK-based multi-disciplinary pain management programme (PMP) when compared with those without litigation.

Method:

Between June 2014 and September 2017, 859 patients attended and completed a 16-day PMP at a tertiary-level National Health Service (UK) pain clinic. Patients were split into two groups: (1) litigation (n = 110) and (2) non-litigation (n = 749). As a part of the assessment procedure, the patients were given a battery of psychological and physical measures to complete over two time points.

Results:

Patients with litigation are statistically significantly more distressed at assessment but make comparable clinically meaningful change in PMP intervention when compared with a non-litigation sample. A very small proportion of the variance in depression scores post-treatment is accounted for by the context of litigation (0.5%), which may be accounted for by employment status. There was no effect of litigation on physical outcome post-intervention.

Discussion:

This article concludes that it is not appropriate to merely assume that the context of litigation results in limited positive psychological and physical outcomes post-PMP. There are some limitations to the clinical sample presented in respect to the conclusions.
No More Taboo: Discursive tactics for navigating the taboo of cosmetic surgery
Authors: Wong Ka Yee Janice
Published: December 2018

Traditionally, in many places around the world, cosmetic surgery is is framed as artificial, man-made, and socially unacceptable. The Korean Wave produces K-pop, K-beauty, and K-fashion, the Korean Wave “Hallyu” has spread rapidly across the globe bringing with it new values about the acceptability of cosmetic surgery and what is considered beautiful and desirable. As a result, cosmetic surgery is now a major export for Korea. This study examines how the Korean aesthetic medical industry and how medical tourists from Hong Kong and Mainland China consume Korean culture and promotional material related to aesthetic medical procedures and in some cases overcome deeply held taboos about cosmetic surgery prevalent in Chinese culture. We find that while Hallyu and the prevalence of social media has indeed influenced consumers standards of beauty, both promoters and consumers of Korean aesthetic medicine must actively work to build the discursive resources to overcome both taboos and perceived risks of undertaking such procedures. Some of the risks and taboos that users actively address include the potential medical risk of cosmetic surgery itself, the social acceptance risk (being judged by friends, family, and the community), and existential risk - admitting that one is ugly or unworthy or that one’s identity may change or completely cease to exist after such a procedure.
A Brief History of the Geography of Education Policy: Ongoing Conversations and Generative Tensions
Authors: Yoon Ee-Seul , Gulson Kalervo , Lubienski Christopher
Published: December 2018

In this article, we map the expansion of geographic approaches in education policy scholarship in the last two decades. Our main objective is to trace key contributions, illuminating moments and turns from multiple epistemological perspectives within the scholarship of education policy and from the field of (human) geography. In doing so, we discuss how different types of methodological frameworks have developed, contributing to new and innovative geospatial methodologies in recent years. Following that, we note the extent to which the reassertion of critical perspectives into geospatial analyses has affected and could affect education policy and scholarship.
HLA epitope mismatch in haploidentical transplantation is associated with decreased relapse and delayed engraftment
Authors: Rimando Joseph , Slade Michael , DiPersio John F. , Westervelt Peter , Gao Feng , Liu Chang , Romee Rizwan
Published: December 2018

HLA disparity is traditionally measured at the antigen or allele level, and its impact on haploidentical hematopoietic cell transplantation (haplo-HCT) with high-dose posttransplant cyclophosphamide (PTCy) is unclear. To the best of our knowledge, the relationship between HLA eplet–derived epitope mismatch (EM) and clinical outcome has not been examined in haplo-HCT. We retrospectively analyzed 148 patients who received a peripheral blood, T-cell–replete haplo-HCT with PTCy at a single center. HLA EM was quantified using an HLAMatchmaker-based method and was stratified by class and vector. The primary outcome was incidence of relapse. The total number of mismatched epitopes (MEs) per patient-donor pair in our patient population ranged from 0 to 51 (median, 24) in the graft-versus-host (GVH) direction and 0 to 47 (median, 24) in the host-versus-graft (HVG) direction. Higher HLA class II EM in the GVH direction was associated with a significantly reduced risk of relapse (adjusted hazard ratio [HR], 0.952 per ME; P = .002) and improved relapse-free survival (adjusted HR, 0.974 per ME; P = .020). Higher HLA class II EM in the HVG direction was associated with longer time to neutrophil (adjusted HR, 0.974 per ME; P = .013) and platelet (adjusted HR, 0.961 per ME; P = .001) engraftment. In peripheral blood haplo-HCT patients, increased HLA EM was associated with a protective effect on the risk of relapse in the GVH direction but a negative effect on time to count recovery in the HVG direction. HLA EM based on the HLA Matchmaker represents a novel strategy to predict clinical outcome in haplo-HCT.
Didactic lectures versus simulation training: a randomised pilot evaluation of its impact on surgical skill
Authors: Supramaniam Prasanna Raj , Mittal Monica , Davies Rebecca , Lim Lee Nai , Arambage Kirana
Published: December 2018

Background

The Bristol enquiry and national surveys have highlighted medicolegal concerns, reduction in training time available for trainees and the change from trainees performing procedures for the first time on patients. The Royal Colleges have taken an active role in advocating the use of simulation training prior to doctors undertaking operative procedures in real time. This study compares didactic lecture-based teaching to simulation training using a quantitative assessment tool.

Method

Randomised pilot study including 20 trainees within their first and second year of Obstetrics and Gynaecology training. The participants were randomised to one of two groups. Group A were taken through the 10 steps to perform a diagnostic laparoscopy with a lecture, followed by an assessment using a laparoscopic pelvic box trainer. Group B were given the same didactic lecture, followed by simulation training in a dry lab, prior to undergoing the same assessment as group A.

Findings

The study demonstrates a statistically significant improvement in the overall OSATS score for trainees undertaking a hands-on simulation training session prior to completing the diagnostic laparoscopy assessment (p = 0.023).

Conclusions

This study clearly demonstrates that exposure to simulation training is superior compared to didactic lecture-based teaching for the acquisition of surgical skills.
Anti-inflammatory effects of empagliflozin in patients with type 2 diabetes and insulin resistance
Authors: Hattori Sachiko
Published: December 2018

Background

Inflammation might be a pathological mediator of cardiovascular events in patients with type 2 diabetes and high cardiovascular risk.

Methods

We investigated whether empagliflozin (EMPA) exerts anti-inflammatory effects that are reflected in decreased high-sensitivity C-reactive protein (hsCRP) values. Patients were allocated to receive a placebo (n = 51) or EMPA (n = 51) as an add-on treatment. Fasting blood samples were collected before and every 3 months after this intervention for 1 year.

Results

Empagliflozin tended to elicit reductions in BMI, HbA1c, aspartate aminotransferase, alanine aminotransferase (ALT), and gamma-glutamyl transpeptidase compared with the placebo, but the differences did not reach statistical significance. Levels of LDL-cholesterol, HDL-cholesterol, and triglycerides were unaltered, significantly increased, and decreased, respectively, by EMPA, but the differences were not statistically significant compared with the placebo. Empagliflozin for 12 months notably reduced the homeostatic model assessment of insulin resistance (HOMA-IR), remnant-like particle cholesterol (RLP-C), and hsCRP by 43%, 52% and 54%, respectively. The time courses of these reductions significantly differed from those of the placebo. Systolic and diastolic blood pressure were also significantly reduced by EMPA compared with the placebo. We applied multiple linear regression analysis to determine which factors were associated with changes in hsCRP induced by EMPA. The results revealed that alterations in hsCRP values (log [hsCRP at 12 months] minus log [hsCRP at month 0]) were significantly associated with changes in HOMA-IR, RLP-C, systolic blood pressure, HDL-C and ALT.

Conclusion

Empagliflozin decreased hs-CRP and lowered levels of remnant related lipoproteins probably via ameliorating insulin resistance. The cardiovascular benefits conferred by EMPA might be driven at least partly by anti-inflammatory effects, and this mechanism might cooperate with other EMPA-induced changes including reduced blood pressure, to achieve the degree of cardioprotection revealed by the EMPA-REG OUTCOME trial.

Trial registration UMIN Clinical Registry (UMIN000021552). Registered 21 March 2016, https://upload.umin.ac.jp/UMIN000021552
A viable hypomorphic Arnt2 mutation causes hyperphagic obesity, diabetes and hepatic steatosis
Authors: Turer Emre E. , San Miguel Miguel , Wang Kuan-wen , McAlpine William , Ou Feiya , Li Xiaohong , Tang Miao , Zang Zhao , Wang Jianhui , Hayse Braden , Evers Bret , Zhan Xiaoming , Russell Jamie , Beutler Bruce
Published: December 2018

Aryl hydrocarbon receptor nuclear translocator 2 (ARNT2) is a member of the basic helix-loop-helix/PER-ARNT-SIM (bHLH/PAS) transcription factor family. ARNT2 heterodimerizes with several members of the family, including single-minded homolog-1 (SIM1) and neuronal PAS domain protein 4 (NPAS4), primarily in neurons of the central nervous system. We screened 64,424 third-generation germline mutant mice derived from N-ethyl-N-nitrosourea (ENU)-mutagenized great-grandsires for weight abnormalities. Among 17 elevated body weight phenotypes identified and mapped, one strongly correlated with an induced missense mutation in Arnt2 using a semidominant model of inheritance. Causation was confirmed by CRISPR/Cas9 gene targeting to recapitulate the original ENU allele, specifying Arg74Cys (R74C). The CRISPR/Cas9-targeted (Arnt2R74C/R74C) mice demonstrated hyperphagia and increased adiposity as well as hepatic steatosis and abnormalities in glucose homeostasis. The mutant ARNT2 protein showed decreased transcriptional activity when coexpressed with SIM1. These findings establish a requirement for ARNT2-dependent genes in the maintenance of the homeostatic feeding response, necessary for prevention of obesity and obesity-related diseases.
A 20-yr database (1997-2017) of co-seismic displacements from GPS recordings in the Aegean area and their scaling with Mw and hypocentral distance
Authors: Ganas Athanassios , Andritsou Nikoletta , Kosma Chrysanthi , Argyrakis Panagiotis , Tsironi Varvara , Drakatos George
Published: December 2018

We describe and make available a dataset of 64 data points of Global Positioning System (GPS) displacements for significant, shallow earthquakes in Greece during the period 1997-2017. The displacement data can be used by earthquake geologists, engineers and seismologists in an effort to better understand the faulting process, the rupture mechanics, the pattern of ground-motions, and in engineering applications. We include recordings from GNSS networks at near-source to regional distances (2–132 km) for 11 earthquakes between global CMT moment magnitudes (Mw) 5.5 and 6.9. We also model the magnitude scaling properties of peak ground horizontal displacements (PGD and PGD-S) for these events using L1-norm minimisation regression. Our data indicate an almost linear attenuation of seismic strain with distance for this range of seismic magnitudes. We developed a set of relationships based on PGD (in cm) and distance to hypocentre R (in km), which may be used for the rapid estimation of the earthquake magnitude in near real-time.MwPGD = [LOG(PGD) + 8.2849]/(1.6810 – 0.2453LOGR)MwPGD-S = [LOG(PGD-S) + 8.0839]/(1.6793 – 0.2447LOGR)
New in Tax Administration Procedures
Authors: Смирнов Е. , Smirnov E.
Published: December 2018

In the summer of 2018, the legislation of Russia regulating the sphere of tax administration was supplemented with federal laws of July 29, 2018 No. 232-FZ and of August 3, 2018 No. 302-FZ, which substantially simplifi ed the procedures for paying taxes and corresponding control by tax authorities.
What does ‘routine post-op neuro obs’ really mean? Establishing a guideline
Authors: Lynch Claire , Gwynn Chloe , Holland Katie , Swift Amelia
Published: December 2018

Background:

Neurosurgery carries a risk of post-operative deterioration that can be detected using neurological observations (NO). NO are frequently requested by surgeons using the phrase ‘routine post-op neuro obs’. There is no agreed definition of what this means.

Aims:

To identify the range of possible interpretations of the phrase ‘routine post-op neuro obs’ by nurses and surgeons.

Method:

National policy analysis, literature review, notes audit and survey methods were used to identify national and local practice. Data were analysed descriptively using Excel.

Findings:

Two out of 15 policies contained observation guidance. Fifteen surgeons used five terms to describe post-operative observations. ‘Routine’ was used to describe observation frequency anywhere between every 15 minutes and every 4 hours. Nurses varied in their interpretation, and frequency was based on clinical judgement.

Conclusion:

Post-operative instructions and nursing practice vary. There is a need and desire for clear evidence-based guidelines to ensure consistency and patient safety.
Exploring therapeutic interventions to reduce the experience of guilt in carers of people living with dementia
Authors: Owen Louise Gillard , Dening Karen Harrison
Published: December 2018

Family carers of people with dementia often describe feelings of guilt, grief and low mood, and are also at increased risk of clinical depression. Through a skilled assessment of a carer's feelings of guilt, an Admiral Nurse identified specific psychological approaches helpful in relieving this potentially damaging and paralysing phenomenon. Person- and family-centred approaches throughout the assessment process, and addressing the needs of individual family members in expressing their individual emotions and experience to the changes in needs of the person with dementia as they become more complex, are essential to family wellbeing. Identifying and differentiating between guilt, anticipatory grief and depression are essential when planning interventions to support family carers.
RESEARCH ROUNDUP
Authors: Costello John
Published: December 2018

John Costello provides a synopsis and brief review of a selection of recently published research articles of interest to neuroscience nurses, highlighting the key points to keep you up to date. A full reference is provided for those who wish to read the research in more detail.
New Scottish plans can help end postcode lottery for LGBT pupils
Authors: Phipps Sam
Published: December 2018

With two in five LGBT pupils in Scottish schools never taught anything about LGBT issues, plans have been approved to offer a genuinely inclusive education. Sam Phipps reports
Compression garments and fabric orthoses for rehabilitation and function: a systematic mapping review
Authors: Snowdon Nicky , Sier Daniel , Potia Tanzila , Wheat Jon , McLean Sionnadh
Published: December 2018

Background/Aims:

Compression garments, joint supports and dynamic-movement orthoses all use elastic fibres and close-fitting designs and have been researched for their effects on movement. There is little cross-referencing between research into these interventions. This review aimed to improve interdisciplinary understanding by analysing key characteristics of the published evidence.

Methods:

Systematic mapping reviews identify gaps in an evidence base and identify questions for more in-depth reviews. This review was conducted in line with current guidance. MEDLINE, CINAHL and Sports Discuss were searched for primary research investigating compression garments and orthoses for movement and function. The following search terms were used: ‘elastane’, ‘spandex’, ‘Lycra’, ‘elastomer*’ ‘Theratog*’, ‘compression’, ‘Neoprene’, ‘orthotic’, ‘orthosis’, ‘shorts’, ‘garment*’, ‘splint’, ‘brace’, ‘sock*’ and ‘stockings’. Studies were screened against predetermined criteria and key study characteristics extracted.

Findings:

A total of 351 studies were selected and analysed. Compression garment research was most common (236 studies), followed by research into joint supports (64 studies) and dynamic-movement orthoses (42 studies). Research largely reflects the purpose for which each intervention was originally designed. Common topics investigated include posture and movement control, proprioception and muscle activity. Pressure applied beneath compression garments was measured in only 30% of studies.

Conclusions:

The review highlights a need for more robust study designs in patient populations and accurate description of interventions. There is a need for a review on the possible effects of compression and support on movement control, which should be used to inform future primary research.
Research roundup: December 2018
Authors: Lean Hettie , Willis Angela , Thurtle Val
Published: December 2018

In this section, a range of brief synopses of recently published articles that may be of interest to health visitors is presented. The aim of this roundup is to provide an overview, rather than a detailed summary, of the research papers selected. Should you wish to look at any of the papers in more detail, a full reference is provided.
Considering the risks to women of domestic abuse
Authors: Noakes Amy
Published: December 2018

Christmas is usually an opportunity for celebration, and spending time with family and friends. However, for some, the holiday period will not provide respite from domestic violence and abuse, says Amy Noakes
Health visitors' experiences supporting multiple birth families: An exploratory study
Authors: Alamad Lara , Denton Jane , Harvey Merryl
Published: December 2018

The aim of this study was to examine health visitors' experiences and the education and professional development needs of health visitors supporting multiple birth families. Two audio-recorded focus groups and a semi-structured telephone interview were undertaken with 14 health visitors working in the West Midlands. A topic guide was used to facilitate a consistent approach, and the recordings were transcribed verbatim and analysed thematically using qualitative methods. Three key themes were generated: My health visiting practice; Perceptions of the impact of multiple birth; and Strategies to support multiple birth families. The study provided an insight into the complex heath visitor role working with multiple birth families, and identified the challenges and more positive aspects of health visitor experiences. The findings will provide the basis for a national survey of health visitors in 2019.
The Balance 2∙f (O) – f (H) as a Cornerstone in Formulation of Electrolytic Systems
Authors: Michałowska-Kaczmarczyk Anna M. , Michałowski Tadeusz
Published: December 2018

The Generalized Electron Balance (GEB) concept, related to electrolytic redox systems, is considered according to principles of Generalized Approach to Electrolytic Systems (GATES). Two equivalent Approaches (I and II) to GEB are presented. The Approach I, when perceived in convention of the card game, is based on the common pool of electrons as money, introduced by electron-active elements, named as players; electron-non-active elements are called there as fans. The GEB obtained according to Approach II results from the linear combination f12 = 2∙f(O) – f(H) of elemental balances: f1 = f(H) for H, and f2 = f(O) for O. Very important properties of f12 are presented here in details, and illustrated by a redox system where comproportion- ation reactions occur
Statistical Taguchi Optimization for Preparation and Adhesion Evaluation of Epoxy Insulator to the Surface of Double Base Propellant Grain
Authors: Babaee Saeed , Monjezi Zahra , Tagharoodi Milad Saadat
Published: December 2018

In this work, Taguchi design (orthogonal array, OA9) was used for the adhesion investigation of an epoxy insulator to a double base (DB) propellant grain. In this manner three epoxy resins based on diglycidylether bisphenol A (DGEBA) and three polyamine curing agents with an active diluent based on DGEBA were used. Therefore, the effects of resin type, curing agent type with its amount and diluent quantity as main factors were investigated on the single lap shear strength (adhesion strength) and then the results were quantitatively evaluated by the analysis of variance (ANOVA). The data given of ANOVA predicted that the best adhesion strength of 15.584 ± 1.606 MPa was obtained for the optimum conditions of MANA POX-102 as epoxy resin, H-37 as curing agent with 57 phr, ERYSYS GE-30 as diluent with 5 phr. In comparison, practical result of adhesion strength obtained for the optimum conditions was 15.4 ± 0.2 MPa. Also the Pull-off test results on the surface of the DB propellant showed that the maximum adhesion strength (related to the optimal conditions) is 2.64 ± 0.2 MPa.
Analisis Produksi Program Berita Indonesia Morning Show di News and Entertainment Television
Authors: Fatmawati Fatmawati
Published: December 2018

Penelitian ini bertujuan untuk mengetahui bagaimana pelaksanaan produksi, proses produksi dan analisis produksi program berita Indonesia Morning Show di NET.TV. Metodologi dalam penelitian ini menggunakan pendekatan kualitatif deskriptif dengan menggunakan paradigma positifis. Data diperoleh melalui proses observasi dengan melakukan proses magang, wawancara baik terstruktur maupun tidak terstruktur dan studi dokumentasi. Dengan menggunankan Teori Hirarki Pengaruh yang diperkenalkan oleh Pamela J. Shoemaker dan Stephen D. Reese, maka penulis akan meneliti apakah ada tekanan dari level rutinitas media terhadap program berita Indonesia Morning Show yang ditinjau dari tiga unsur, yakni : Audiens (Consumers), Organisasi Media (Processor), dan Sumber Berita (Suppliers). Setelah melakukan penelitian Indonesia Morning Show dalam memproduksi programnya melalui tiga tahap, yakni : Pra-produksi, Produksi dan Pasca-produksi. Dilihat dari teori hirarki pengaruh level media rutin dalam proses produksi program berita Indonesia Morning Show di pengaruhi 3 unsur, yaitu : Audiens, Organisasi Media dan Sumber Berita. Dan pengemasan berita yang biasannya menggunakan format 5w+1H tim redaksi Indonesia Morning Show merubahnnya menjadi format S-P-O-K guna mendapatkan kesan berita yang mudah untuk diterima oleh audiens di pagi hari.Kata Kunci: Analisis Produksi, Teori Hirarki Pengaruh, Audiens, Organisasi Media, Sumber Berita.  This study aims to find out how the implementation of production, production process and production analysis of Indonesia Morning Show news program on NET.TV. The methodology in this research uses descriptive qualitative approach using positivist paradigm. Data obtained through the process of observation by apprenticeship process, structured and unstructured interviews and documentation studies. Using the Influence Hierarchy Theory introduced by Pamela J. Shoemaker and Stephen D. Reese, the authors will examine whether there is any pressure from the level of media routines on the Indonesia Morning Show news program in terms of three elements: Audiences (Consumers), Media Organizations (Processor), and Source news (Suppliers). After conducting research, Indonesia Morning Show in producing the program through three stages, namely: Pre-production, Production and Post-production. Judging from hierarchical theory, the influence of routine media level in the production process of Indonesian Morning Show news program influenced 3 elements, namely: Audience, Media Organization and News Sources. And the news packaging that usually uses the 5w + 1H format of the Indonesia Morning Show editorial team transforms it into S-P-O-K format to get an easy news impression to be received by an audience in the morning. Keywords: Production Analysis, Hierarchy Theory of Influence, Audience, Media Organization, Source of News.
Dinamika Peran Jejaring Pengelolaan Sampah Dalam Komunikasi Literasi Sampah
Authors: Antin Titi , Wahyuni Hermin Indah , Partini Partini
Published: December 2018

Sampah merupakan masalah ekologi yang harus ditangani secara komprehensif, baik oleh Pemerintah maupun oleh peran aktif masyarakat yang direpresentasikan dalam Jejaring Penggelolaan Sampah Mandiri (JPSM). Peran JPSM sangat dibutuhkan dalam mewujudkan masyarakat yang melek sampah. Oleh sebab itu  penelitian ini bertujuan untuk mengeksplorasi peran Jejaring Pengelolaan Sampah Mandiri (JPSM) “AMOR” di Kabupaten Bantul dalam membangun kesadaran masyarakat untuk mengelola sampah mulai dari sumbernya yaitu rumah tangga serta untuk memetakan pola komunikasi dalam jejaring pengelolaan sampah tersebut. Untuk menjawab tujuan, maka digunakan metode kualitatif dengan teknik pengumpulan data seperti wawancara, observasi, dan focus group discussion dengan teori komunikasi partisipatif. Dari hasil penelitian diketahui bahwa peran JPSM “AMOR” dalam komunikasi literasi sampah adalah sebagai fasilitator antara pemerintah dan masyarakat serta sebagai agen pemberdayaan melalui pola komunikasi pada level makro dan mikro.Kata kunci: JPSM, pengelolaan sampah, komunikasi partisipatif.Waste is an ecological problem which has to be overcome comprehensively, both by the government and society which manifested in independent waste management network (JPSM). The role of JPSM is very crucial in generating society awareness. Therefore  this study aims to explore the role of JPSM “AMOR” in Bantul district in developing society awareness to manage the waste started from the household and also to apply the communication pattern in in waste management networking. To achieve the goal, qualitative method was employed by using data collecting method such as interview, observation and focus group discussion with the theory of participative communication. From the study it was obtained that the role of JPSM “AMOR” in communication of waste literation as a facilitator between government and society and also as empowerment agent through communication group at macro and micro level.Keywords: JPSM, waste management, participative communication.
Factores asociados al emprendimiento por oportunidad de colombianos retornados del exterior
Authors: Tovar Cuevas Luis Miguel , Serna Borja Walter , Balanta Cobo Sandra , Ordoñez José Alejandro
Published: December 2018

El propósito de este trabajo es explorar, a partir de los datos de la encuesta GEM 2012, los factores que pueden afectar la probabilidad de que un colombiano que ha retornado al país, sea emprendedor por oportunidad. La exploración se hizo a partir de la estimación de modelos de respuesta binaria. Los resultados muestran que las variables que mejor explican que un migrante retornado emprenda por oportunidad son: las expectativas positivas en el país para la creación de empresas en un horizonte de seis meses, los ahorros, y los contactos realizados durante su permanencia en el exterior. Este trabajo es uno de los primeros en abordar los factores que afectan la probabilidad de que los migrantes retornados sean emprendedores por oportunidad, sin embargo, no deja de ser de carácter exploratorio, debido a las limitaciones en las fuentes de información disponibles. Se requieren más investigaciones que profundicen en el tema.
Evidence Beyond the Rules: A Critical Thinking Approach to Teaching Evidence Law to Undergraduate Students
Authors: Arnott Stephen
Published: December 2018

This article suggests that using a critical thinking approach in teaching undergraduate courses such as Evidence is not only consistent with education in the liberal arts but offers valuable opportunities to enhance student learning, develop transferable skills, and explore interdisciplinary connections.
Combining Complementary and Related Expertise in Transdisciplinary Projects
Authors: Maurer Moritz
Published: December 2018

A combination of complementary and related expertise ensured the success of the workshop The City and Agriculture. Renewing the Dialogue. Can this insight be applied to transdisciplinary research in general?
Humanökologisches Reallabor für Klimafolgenanpassung in Emmendingen
Authors: Serbser Wolfgang H. , Hofmann Klaus Markus
Published: December 2018

Bei der dritten Sommeruniversität 2018 Urban Concepts in Sustainable Transition des European College of Human Ecology(COHE) und der Deutschen Gesellschaft für Humanökologie(DGH) demonstrierte die junge Generation ihre Konzepte für eine nachhaltige und klimaresiliente
Entwicklung der Stadt Emmendingen und überzeugte Bürger(innen) und Presse. Das COHE nimmt damit konkrete Formen an.
Potenziale und Perspektiven der Nachhaltigkeitsforschung an deutschen Fachhochschulen
Authors: Ringel Marc , Kesselring Sven , Roth Michael
Published: December 2018

Hochschulen für angewandte Wissenschaften sind aufgrund ihres Profils besonders befähigt, angewandte Nachhaltigkeitsforschung zu betreiben und Forschungsergebnisse in die Praxis zu tragen. Wissenschaftler(innen), die an diesen Hochschulen forschen, lehren und mit Praxispartnern
zusammenarbeiten, sind kompetente Ansprechpartner(innen) für die Politik und können in parlamentarischen Anhörungen eine Vermittlerrolle einnehmen.
Wider das Kastenwesen: Für mehr institutionelle Durchlässigkeit zwischen Universität und Fachhochschule
Authors: Imboden Dieter M.
Published: December 2018

Der Unterschied zwischen Fachhochschulen und universitären Hochschulen, wie er sich vor allem in der Ausstattung mit Forschungsmitteln und beim Promotionsrecht zeigt, hat historische Ursachen. Angesichts der allgemein wachsenden Hochschulquoten wäre es sinnvoll, den heutigen
Graben zuzuschütten, das Hochschulsystem als Kontinuum verschiedener Stufen zu betrachten und den einzelnen Institutionen die Möglichkeit einzuräumen, sich im Laufe der Zeit entlang dieses Kontinuums zu verschieben.
Understanding the “philosophy” of laboratory hemostasis
Authors: Lippi Giuseppe , Adcock Dorothy , Favaloro Emmanuel J.
Published: December 2018

Unlike many other areas of laboratory medicine, laboratory hemostasis has some peculiarities, which makes it one of the most complex diagnostic domains in clinical medicine. The inherent complexity of the hemostasis process, the components of which have not yet been thoroughly unravelled, is mirrored by a large number of hemostasis disturbances, which can involve single or multiple components. Although laboratory diagnostics represents an unavoidable part of the diagnostic reasoning in patients with bleeding or thrombotic disorders, the basic concept beneath the assumption that in many human pathologies, one single test may be sufficient for the diagnosis, does not hold true in hemostasis. There are in fact many aspects that would lead us to conclude that laboratory hemostasis can be considered a very challenging arena for many clinicians and perhaps also for some laboratory professionals. The most challenging aspects typically include the following concepts; that hemostasis is an intricate and multifaceted process, that more than one test is typically needed to achieve a final diagnosis, that results of screening tests depend on many biological factors and do not allow making a final diagnosis, that harmonization of techniques is still an unmet target, and that the calculations used vary widely among laboratories. This article is hence aimed at discussing many of these aspects, with the hope of presenting a useful contribution to better understand the “philosophy” of laboratory hemostasis.
The biopsychosocial condition of childhood cancer survivors in the transition towards adult care: a national survey from the joint pediatric and adult transition care group
Authors: Zucchetti Giulia , Bellini Simona , Bertolotti Marina , Biasin Eleonora , Brignardello Enrico , Fagioli Franca
Published: December 2018

Background

To provide successful transfer from childhood to adult-oriented healthcare is one of the priorities of survivorship care plans.

Purpose

This study describes adolescent and young adult childhood cancer survivors’ conditions at the moment of the transition to adult care deepening their biological, psychological, social and assistant state and their associations with socio-demographic and clinical characteristics.

Methods

A biopsychosocial check-list in four health domains (biological, psychological, social and assistant) was filled in by healthcare professionals (oncologists, psychologists, social workers and nurses) through qualitative interviews and clinical observations of 79 survivors (58% boys; Mage = 20 years old) at the moment of the transition from the Pediatric Oncology Unit to the Transition Unit of the Childhood Cancer Survivors.

Results

At the moment of transition, 38% of survivors showed a positive condition in all the four health domains without any kind of impairment. Biological (37%) and psychological areas (44%) were found to be those with major incidence of impairments. Association phenomena were found between psychological and social condition (p < 0.05) and between social and assistant condition (p < 0.05). Biological condition was also significantly associated with the type of cancer (χ = 6,2414, p < 0.05).

Conclusion

Although many survivors entered in adult care system without any impairment, the biopsychosocial approach highlighted that there is a presence of impairments in at least one of the main health domains.
Impartial achievement games for generating nilpotent groups
Authors: Benesh Bret J. , Ernst Dana C. , Sieben Nándor
Published: December 2018

We study an impartial game introduced by Anderson and Harary. The game is played by two players who alternately choose previously-unselected elements of a finite group. The first player who builds a generating set from the jointly-selected elements wins.
We determine the nim-numbers of this game for finite groups of the form

T
×
H

{T\times H}

, where T is a 2-group and H is a group of odd order. This includes all nilpotent and hence abelian groups.
A class of homotopy with regularization for nonlinear ill-posed problems in Hilbert space
Authors: Liu Minghui , Ma Fuming
Published: December 2018

Nonlinear ill-posed problems arise in many inverse problems in Hilbert space. We investigate the homotopy method, which can obtain global convergence to solve the problems. The “homotopy with Tikhonov regularization” and “homotopy without derivative” are developed in this paper. The existence of the homotopy curve is proved. Several numerical schemes for tracing the homotopy curve are given, including adaptive tracing skills. Compared to the regularized Newton method, the numerical examples show that our proposed methods are stable and effective.
Semi-heuristic parameter choice rules for Tikhonov regularisation with operator perturbations
Authors: Hämarik Uno , Kangro Urve , Kindermann Stefan , Raik Kemal
Published: December 2018

We study the choice of the regularisation parameter for linear ill-posed problems in the presence of data noise and operator perturbations, for which a bound on the operator error is known but the data noise level is unknown. We introduce a new family of semi-heuristic parameter choice rules that can be used in the stated scenario. We prove convergence of the new rules and provide numerical experiments that indicate an improvement compared to standard heuristic rules.
No clinical utility of common polymorphisms in IGF1, IRS1, GCKR, PPARG, GCK1 and KCTD1 genes previously associated with insulin resistance in overweight children from Romania and Moldova
Authors: Chirita-Emandi Adela , Munteanu Diana , Andreescu Nicoleta , Tutac Paul , Paul Corina , Velea Iulian Puiu , Pusztai Agneta Maria , Hlistun Victoria , Boiciuc Chiril , Sacara Victoria , Vudu Lorina , Usurelu Natalia , Puiu Maria
Published: December 2018

Background

Previous genome-wide association studies (GWAS) identified IGF1, IRS1, GCKR, PPARG, GCK1 and KCTD1 as candidate genes for insulin resistance and type 2 diabetes (T2D). We investigated the associations of these previously reported common variants in these genes with insulin resistance in overweight children from Romania and Moldova.

Methods

Six single nucleotide polymorphisms (SNPs), IGF1 (rs35767), IRS1 (rs2943634), GCKR (rs780094), PPARG (rs1801282), GCK1 (rs1799884) and KCTD15 (rs29941), were genotyped in 100 overweight children along with clinical and metabolic parameters. Homeostatic model assessment of insulin resistance (HOMA-IR) above 3.4 (defining insulin resistance) was used as the outcome.

Results

Children differed in insulin resistance status despite having similar body mass index (BMI) standard deviation scores (SDS) (World Health Organization, [WHO] reference). The identified predictors for altered insulin metabolism were higher cholesterol levels, higher diastolic blood pressure and higher waist-to-hip-ratio (as a marker for increased abdominal fat). None of the SNPs showed significant association with increase in the risk for insulin resistance in children (p range=0.478–0.724; odds ratio [OR] range=1.924–4.842); however, the risk allele in GCKR (rs780094, p=0.06, OR=6.871) demonstrated near statistical significance.

Conclusions

The interrogated risk alleles did not show any significant association with insulin resistance in children in our cohort; however, the GCKR (rs780094) might be a viable candidate in larger cohorts. The lack of replication of the proposed association may point to differences in linkage disequilibrium or effect modifiers across studies.
Assessment of Motor Capacity in the Competition Period – Female Sports Games (Soccer and Rugby Sevens)
Authors: Radu Liliana-Elisabeta , Ursanu Grigore , Popescu Veronica
Published: December 2018

In the rugby and soccer sevens, players need special motor capacities, such as aerobic and anaerobic resistance, proper force in the muscles that work during game actions, as well as speed and agility. The purpose of the papers was to assess the motor capacity in the competition period, among female athletes who practice team sports. The study comprised 26 subjects, 12 of whom activate in the female rugby team of CS Politehnica Iasi, and 14 of whom belong to the soccer team of Naviobi Iasi. Both teams are champions in their leagues. We applied the following tests: 250m run, long jump without take-off, throwing the 2kg medicine ball, 30second abdominals, and 5m back and forth run. The data obtained were interpreted in SPSS 20.0 for IBM, by applying the t test for independent samples. Results have shown a significant difference (p<0.05). Significant differences were found only for the test that measured the force of abdominal muscles for which the female rugby players scored significantly higher than the rest. In all the other tests, the mean results were similar or very close. We found that the motor experience within the game influenced the results obtained, just like general physical training; they are both important for supporting the specific effort. The tests we applied mid-competition period.
INFLUÊNCIA DO PLANEJAMENTO FINANCEIRO NAS DECISÕES ECONÔMICAS DE UNIVERSITÁRIOS DE ADMINISTRAÇÃO EM CARUARU – PE
Authors: Da Silva Maria de Fátima
Published: December 2018

Este artigo apresenta os resultados de pesquisa que objetivou destacar a importância da educação financeira para a tomada de decisões conscientes e mais responsáveis, que propiciam o desenvolvimento econômico pessoal. A execução deste estudo possibilitou identificar de que forma os alunos do curso de Administração de uma instituição de ensino superior de Caruaru - PE (UNIFAVIP) realizam seu planejamento financeiro. Como resultado, identificou-se uma gestão financeira eficiente e um perfil de consumo consciente por parte dos pesquisados.
EDUCAÇÃO PARA OS RECURSOS HÍDRICOS E A DEGRADAÇÃO DO RIO BOTAS
Authors: De Mello Rafael , Reis Danielle , Pereira Mello Silvia , Friede Reis
Published: December 2018

A educação ambiental busca alcançar um mundo mais sustentável por meio da mudança de comportamentos dos diversos segmentos da sociedade. Dentro dessa perspectiva, o projeto Implicações no ambiente no processo de ensino-aprendizagem atua em várias escolas buscando a conscientização dos jovens sobre o uso sustentável dos Recursos Hídricos por meio de oficinas que possam gerar consciência crítica nos alunos. Esse artigo discute o trabalho realizado por esse projeto em escola pública no município de nova Iguaçu com vistas à conscientização de alunos em relação ao Rio Botas.
O PAPEL DE UMA ABORDAGEM MULTIDISCIPLINAR NA EDUCAÇÃO INCLUSIVA: RELATO DE CASO
Authors: D'Arc Moreira Arcanjo Ana , Junior Carlos Alberto Morão , Cerqueira Mármora Claudia
Published: December 2018

Este artigo refere-se a um estudo de caso envolvendo o atendimento psicológico clínico de uma criança de oito anos, sexo masculino, com diagnóstico prévio de transtorno de déficit de atenção e hiperatividade (TDAH). Buscou-se promover uma discussão sobre as práticas pedagógicas da educação inclusiva e seus efeitos no desenvolvimento escolar, desde o encaminhamento até o tratamento a partir de uma perspectiva de integração multidisciplinar, a qual entende o processo de ensino-aprendizagem como interação entre os estímulos provenientes do meio externo e o cérebro. Com base na análise deste caso, concluiu-se que as práticas inclusivas devem ser incorporadas a partir da colaboração entre as áreas da psicologia, neurociências e educação com um olhar dirigido à maneira de aprender da criança com TDAH.
Ethnic differences in regional adipose tissue oestrogen receptor gene expression
Authors: Goedecke Julia H , Tootla Mehreen , Keswell Dheshnie
Published: December 2018

Studies have shown ethnic differences in body fat distribution, characterised by greater peripheral and less central fat accumulation in black compared to white South African (SA) women. As sex hormones play an important role in body fat distribution, our study aimed to determine whether differences in body fat distribution between black and white SA women were associated with subcutaneous adipose tissue (SAT) expression of oestrogen receptors (ERA and ERB) and aromatase (CYP19A1). Body fat distribution (DXA and CT) and ERA, ERB and CYP19A1 expression in abdominal and gluteal SAT were measured in 26 black and 22 white SA women. Abdominal SAT ERA and ERB did not differ by ethnicity or BMI. Gluteal ERA was higher (1.08 ± 0.06 vs 0.99 ± 0.05, P < 0.001) and ERB was lower (0.99 ± 0.06 vs 1.10 ± 0.07, P < 0.001) in black vs white SA women. CYP19A1 increased with obesity in all depots (P < 0.001). In both black and white SA women, gluteal ERA was associated with lower central fat mass (FM) and greater gynoid FM (P < 0.05), while the inverse association was shown for CYP19A1 in all depots (P < 0.01). In conclusion, ethnic differences in gluteal ERA expression were associated with differences in body fat distribution previously reported between black and white SA women.
The depot-specific and essential roles of CBP/p300 in regulating adipose plasticity
Authors: Namwanje Maria , Liu Longhua , Chan Michelle , Aaron Nikki , Kraakman Michael J , Qiang Li
Published: December 2018

Fat remodeling has been extensively explored through protein deacetylation, but not yet acetylation, as a viable therapeutic approach in the management of obesity and related metabolic disorders. Here, we investigated the functions of key acetyltransferases CBP/p300 in adipose remodeling and their physiological effects by generating adipose-specific deletion of CBP (Cbp-AKO), p300 (p300-AKO) and double-knockout (Cbp/p300-AKO) models. We demonstrated that Cbp-AKO exhibited marked brown remodeling of inguinal WAT (iWAT) but not epididymal WAT (eWAT) after cold exposure and that this pattern was exaggerated in diet-induced obesity (DIO). Despite this striking browning phenotype, loss of Cbp was insufficient to impact body weight or glucose tolerance. In contrast, ablation of p300 in adipose tissues had minimal effects on fat remodeling and adiposity. Surprisingly, double-knockout mice (Cbp/p300-AKO) developed severe lipodystrophy along with marked hepatic steatosis, hyperglycemia and hyperlipidemia. Furthermore, we demonstrated that pharmacological inhibition of Cbp and p300 activity suppressed adipogenesis. Collectively, these data suggest that (i) CBP, but not p300, has distinct functions in regulating fat remodeling and that this occurs in a depot-selective manner; (ii) brown remodeling occurs independently of the improvements in glucose metabolism and obesity and (iii) the combined roles of CBP and p300 are indispensable for normal adipose development.