bluuebunny/crossref_metadata_2025 huggingface dataset:
Count de Lubersac: Mission in Russia, 1916–1919
Authors: Pavlov Andrey
Published: May 2023

The author examines the activities of Count Jean de Lubersac, a member of the French military mission in Russia, and demonstrates how the main stages of his activities in that position vividly illustrate the evolution of French policy towards Russia in the critical years of Franco-Russian relations. Published in August 1918, “A Letter to American Workingmen” by Vladimir Lenin mentions his meeting with two French officers in February of the same year. One of them, Jacques Sadoul, is fairly well known, while the personality and area of activity of the other has not yet attracted the same degree of research interest. Meanwhile, his name, Jean de Lubersac, is mentioned in the memoirs of many French and Russian military and political figures when describing the events of 1916–1919 in Russia. Arriving in Russia as a mere second lieutenant on an air mission, this highly enterprising man quickly took up a position in the Russian Fifth Army, then in the French military mission and finally in the ranks of the interventionists in northern Russia. It was a most unusual feat for a junior officer, especially one from abroad. The primary sources for the study include the memoirs of those French and Russian nationals who knew de Lubersac personally, as well as documents from French and Russian archives. Although these sources contain only sketchy accounts, together they provide a fairly complete picture of what Jean de Lubersac was doing in Russia, not only in 1916–1919, but also later, in 1922.
Integration of the USSR into the International Patent-Licensing System in the Context of International Technological Cooperation (1950s – early 1970s)
Authors: Zavodyuk Svetlana
Published: May 2023

In the 1950s, as the world entered an era of scientific and technological revolution, the leadership of the Soviet Union chose a new economic course based on scientific knowledge, which could enable the USSR to secure technological leadership, a competitive advantage over Western countries and closer integration with the CMEA. A key indicator of the success of this policy has been the country’s incorporation into the evolving system of international patenting and licence selling. In previous years, these processes had not been covered in historical academic publications. The purpose of this study is to explore the Soviet Union's entry into the international patent licensing system and related organizational, legislative and information measures drawing on the archival documents, including the All-Union Research Institute for State Patent Examination (VNIIGPE), introduced into the academic circuit for the first time, as well as on the published reports of the 1965 meeting of the Committee of Experts on Author's Certificates and the Washington Conference of 1970. The author demonstrates that in the 1950s and 1960s the USSR made the transition from a model of institutional and legal incorporation into international patent-licensing activity to an integration model based on patent cooperation and standardisation, in accordance with international norms. The reason for the slow development of technological cooperation, which hindered the achievement of ambitious goals, was the inertia and internal costs of the Soviet economic and administrative system, which fully affected the development of both models. Ultimately, changes in the international environment and the slowdown of economic development in the USSR in the early 1970s prevented the country from gaining even modest benefits from integration.
Small Wars of the Great Powers: Charles Edward Callwell and the Russian Empire in Comparative Perspective
Authors: Malkin Stanislav
Published: May 2023

In this article the author focuses on the semantic and substantive aspects of the colonial conflict analysis model presented in the work of the British Army Major General Charles Edward Collwell, “Small Wars: Their Principles and Practices”, which became the most notable British treatise on the subject at the turn of the nineteenth and twentieth centuries. A distinctive feature of the work is the comparative approach to the analysis of the British colonial wars fought in the Victorian era. It is established that the Russian case (the annexation of Central Asia and the pacification of the North Caucasus) is a golden thread running through all sections of the work, serving, along with similar examples from French, Spanish, and US history, as a kind of tuning fork for the universal principles of successful small warfare that Callwell laid out in his work. The aim of the paper is to form a more substantive account of the significance of comparative colonialism for British military thinking and the place of the Russian experience in its evolution. The study has shown that “Small Wars” reflected a course towards the normalisation of the Russian Empire within a professional discourse. In addition, the historiography focuses on Callwell's selective approach to the choice of factual material and its place in the evolution of British counterinsurgency. In this article, the author focuses on identifying the reasons for differences in the forms and ways of systematizing the experience of small wars in the colonial and frontier policies of both the Russian and British empires. Particular attention is paid to the circumstances that led to the gradual loss of Callwell's work to its former importance on the eve and after the Great War.
Improving Mathematics Learning Outcomes Using The Mind Mapping Method for Students of SMPN 8 Denpasar
Authors: Widana I Wayan , Umam Eka Koirul
Published: May 2023

This study is a classroom action research that aims to improve mathematics learning outcomes. The research was conducted at SMPN 8 Denpasar, which is located on Jl. Meduri No. 2, Sumerta Village, East Denpasar District, Denpasar City, Bali. The research subjects were 40 class VIII-A students of SMPN 8 Denpasar semester 2 of the 2022/2023 academic year. The object of research is the mathematics learning outcames. Data on learning outcomes were collected using tests, and analyzed descriptively qualitatively. Criteria for the success of the research: (a) the average value of class is at least to classical completeness criteria of 70 and (b) classical completeness of at least 85%. The results showed that in the first cycle the average value of class was 73.70 with classical completeness 52.50%; in cycle II the average value of class was 81.30 with classical completeness of 87.50%. Thus, it can be concluded that the Mind Mapping method is able to improve the mathematics learning outcomes of class VIII-A students of SMPN 8 Denpasar semester 2 of the 2022/2023 academic year in 2 cycles.
PRAKTIK EUTANASIA DALAM PERSPEKTIF MEDIS DAN HUKUM PIDANA INDONESIA
Authors: Alam Kodrat , Saputra Ade Tian Dwi
Published: May 2023

Some think that euthanasia is an act of suicide or intentionally taking someone's life which is prohibited by any religion and unlawful. The Indonesian Doctors Association (IKI) also opposes euthanasia measures for patients for any reason. Broadly speaking from the way it is done, euthanasia is divided into two groups, namely active euthanasia and passive euthanasia. According to Kartono Muhammad, active euthanasia occurs if there are still signs of life in patients when euthanasia measures are performed. The action referred to in this case is to accelerate the death of a person by giving injections or removing the aids used by the patient. Meanwhile, passive euthanasia is an action that is carried out both at the request of the patient himself and the patient's family to deliberately no longer assist with tools that can prolong the patient's life.
DISPARITAS PUTUSAN HAKIM PIDANA BERKUALITAS YANG MENCERMINKAN RASA KEADILAN DALAM SISTEM HUKUM INDONESIA
Authors: Kusyandi Adi , Yamin Saefullah
Published: May 2023

Republic of Indonesia as required in Article 24 of the Republic of Indonesia. Indonesia. Judges are free from any coercion and/or pressure from anyone in carrying out their judicial but are free to do whatever they want. The principle of freedom of judges refers to the independence or independence of the judiciary to provide objective and fair decisions. Indonesian judges understand and carry out the meaning of the freedom of judges by carrying out the main duties of judicial power in accordance with procedural law and applicable law, namely freedom of responsibility, corridors of freedom of order in applicable laws and regulations, freedom from government, and interests. groups, pressure groups, print media influence, electronic media, and influential individuals.
Haematological Parameters in Preterm Neonates Admitted in Neonatal Intensive Care Unit in a Tertiary Care Hospital
Authors: Parikh Dwepa Kamlesh , Nisal Amit Ravindra , Nimbargi Ravindra Chandrashekhar
Published: May 2023

Though reference haematological parameters are defined for neonates, ranges vary in preterm. Few data are available regarding the premature population during the first month of life. Objective: To observe the variation in haematological parameters concerning different gestational ages, birth weights and gender among preterm neonates admitted to NICU with common illnesses like respiratory distress (RDS), neonatal hyperbilirubinemia (NNH) and sepsis in a tertiary care hospital. A total of ninety preterm neonates admitted to the neonatal intensive care unit (NICU) were analyzed over two years. Complete blood counts were obtained, grouped and analyzed according to the underlying diagnosis of sepsis, NNH and RDS. Clinical data were also extracted. The data were analyzed using SPSS software version 25. Mean, Chi-square test and ANOVA tests were used for data analysis. P value <0.05 was considered significant. Result: Variation was seen concerning gestational age and birth weight. Eosinophils were significantly decreased in LBW, while a decrease in neutrophils and an increase in lymphocyte count were seen in EPT. Haemoglobin and RBC indices also showed significant variation according to birth weight. Conclusions research complete blood counts of preterm depend on the degree of prematurity, birth weight, and other clinical findings.
Zugehörigkeitsmaschinen – Zur Bedeutung von Gefühlen und Emotionen im Fußball
Authors: Brandt Christian , Wetzels Michael
Published: May 2023

In der sozialwissenschaftlichen Forschung zu Fußballfans ist das Konzept der Identität seit Jahren virulent, obwohl es vielfältig kritisiert wurde. Wir möchten diese Forschung erweitern, indem wir zwei Fallstudien zu Fans von Hertha BSC (1. Bundesliga) und dem HFC Falke (8. Liga) mit dem Konzept von Zugehörigkeit verbinden. Dies hat zwei Vorteile: Zum einen verstärken wir die Bedeutung von Gefühlen und Emotionen, die ethnosemantisch immer wieder im Feld des Fußballs betont werden und mehr hervorheben als dies im Konzept von Identität der Fall ist. Zum anderen zeigen unsere Fallstudien anhand des Torjubels, dass auch wenn wir zunächst typische Formen der Erzeugung von Zugehörigkeit sehen, sich dennoch, bedingt durch die unterschiedlichen Milieus und Geschichten beider Vereine, zwei unterschiedliche Handlungsformen beschreiben und analysieren lassen.
Individual recombinant repeats of MUC16 display variable binding to CA125 antibodies
Authors: Wang Chien-Wei , Hanson Eliza K. , Minkoff Lisa , Whelan Rebecca J.
Published: May 2023

BACKGROUND: Despite its importance in the clinical management of ovarian cancer, the CA125 biomarker – located on the mucin protein MUC16 – is still not completely understood. Questions remain about MUC16’s function and structure, specifically the identity and location of the CA125 epitopes. OBJECTIVE: The goal of this study was to characterize the interaction of individual recombinant repeats from the tandem repeat domain of MUC16 with antibodies used in the clinical CA125 II test. METHODS: Using E. coli expression, we isolated nine repeats from the putative antigenic domain of CA125. Amino acid composition of recombinant repeats was confirmed by high-resolution mass spectrometry. We characterized the binding of four antibodies – OC125, M11, “OC125-like,” and “M11-like” – to nine recombinant repeats using Western blotting, indirect enzyme-linked immunosorbent assay (ELISA), and localized surface plasmon resonance (SPR) spectroscopy. RESULTS: Each recombinant repeat was recognized by a different combination of CA125 antibodies. OC125 and “OC125-like” antibodies did not bind the same set of recombinant repeats, nor did M11 and “M11-like” antibodies. CONCLUSIONS: Characterization of the interactions between MUC16 recombinant repeats and CA125 antibodies will contribute to ongoing efforts to identify the CA125 epitopes and improve our understanding of this important biomarker.
Associations of anemia and blood transfusions with mortality in old, critically ill COVID-19 patients – Results from the prospective COVIP Study
Authors: Erkens Ralf ,   COVIP study group, Duse Dragos , Wernly Bernhard , Flaatten Hans , Fjølner Jesper , Bruno Raphael Romano , Wolff Georg , Artigas Antonio , Kelm Malte , Beil Michael , Sviri Sigal , Schaller Stefan J. , Fuest Kristina , Szczeklik Wojciech , Piayda Kerstin , Elhadi Muhammed , Joannidis Michael , Nedergaard Helene Korvenius , Oeyen Sandra , Moreno Rui , Leaver Susannah , de Lange Dylan W. , Guidet Bertrand , Jung Christian
Published: May 2023

Aims: Anemia is common in the old and often observed in critically ill patients. Increased age is associated with higher mortality following a COVID-19 infection, making old patients prone to poor outcomes. We investigated whether anemia at admission to the ICU or the need for blood transfusion was associated with 90-day mortality in older, critically ill COVID-19 patients. Methods: In this prospective multicenter study, the 90-day mortality of COVID-19 patients≥70 years treated in 138 intensive care units (ICU) was analyzed. Associations between anemia (WHO definition) at admission and discharge from ICU and the use of red blood cell (RBC) transfusions with mortality were assessed. Hemoglobin thresholds of RBC transfusions in old, critically ill COVID-19 patients were recorded. Results: In 493 patients (350 anemic, 143 non-anemic), anemia (WHO definition) at the time of ICU admission was not associated with impaired overall survival. Transfusion and severe anemia (hemoglobin≤10 g/dL) at ICU discharge were independently associated with a higher risk of 90-day mortality. Conclusion: The need for red blood cell transfusions and severe anemia at ICU discharge, but not at the timepoint of admission, were independently associated with 90-day mortality in critically-ill old COVID-19 patients.
Medial Temporal Lobe Atrophy in Predementia Alzheimer’s Disease: A Longitudinal Multi-Site Study Comparing Staging and A/T/N in a Clinical Research Cohort
Authors: Jarholm Jonas Alexander , Bjørnerud Atle , Dalaker Turi Olene , Akhavi Mehdi Sadat , Kirsebom Bjørn Eivind , Pålhaugen Lene , Nordengen Kaja , Grøntvedt Gøril Rolfseng , Nakling Arne , Kalheim Lisa F. , Almdahl Ina S. , Tecelão Sandra , Fladby Tormod , Selnes Per
Published: May 2023

Background:

Atrophy of the medial temporal lobe (MTL) is a biological characteristic of Alzheimer’s disease (AD) and can be measured by segmentation of magnetic resonance images (MRI).

Objective:

To assess the clinical utility of automated volumetry in a cognitively well-defined and biomarker-classified multi-center longitudinal predementia cohort.

Methods:

We used Automatic Segmentation of Hippocampal Subfields (ASHS) to determine MTL morphometry from MRI. We harmonized scanner effects using the recently developed longitudinal ComBat. Subjects were classified according to the A/T/N system, and as normal controls (NC), subjective cognitive decline (SCD), or mild cognitive impairment (MCI). Positive or negative values of A, T, and N were determined by cerebrospinal fluid measurements of the Aβ42/40 ratio, phosphorylated and total tau. From 406 included subjects, longitudinal data was available for 206 subjects by stage, and 212 subjects by A/T/N.

Results:

Compared to A–/T–/N– at baseline, the entorhinal cortex, anterior and posterior hippocampus were smaller in A+/T+orN+. Compared to NC A– at baseline, these subregions were also smaller in MCI A+. Longitudinally, SCD A+ and MCI A+, and A+/T–/N– and A+/T+orN+, had significantly greater atrophy compared to controls in both anterior and posterior hippocampus. In the entorhinal and parahippocampal cortices, longitudinal atrophy was observed only in MCI A+ compared to NC A–, and in A+/T–/N– and A+/T+orN+ compared to A–/T–/N–.

Conclusion:

We found MTL neurodegeneration largely consistent with existing models, suggesting that harmonized MRI volumetry may be used under conditions that are common in clinical multi-center cohorts.
Best Medicine for Dementia: The Life-Long Defense of the Brain
Authors: Andersson Marcus J. , Stone Jonathan
Published: May 2023

This review deals with an unwelcome reality about several forms of dementia, including Alzheimer’s disease— that these dementias are caused, in part or whole, by the aging of the vasculature. Since the vasculature ages in us all, dementia is our fate, sealed by the realit!ies of the circulation; it is not a disease with a cure pending. Empirically, cognitive impairment before our 7th decade is uncommon and considered early, while a diagnosis in our 11th decade is late but common in that cohort (>40%). Projections from earlier ages suggest that the prevalence of dementia in people surviving into their 12th decade exceeds 80%. We address the question why so few of many interventions known to delay dementia are recognized as therapy; and we try to resolve this few-and-many paradox, identifying opportunities for better treatment, especially pre-diagnosis. The idea of dementia as a fate is resisted, we argue, because it negates the hope of a cure. But the price of that hope is lost opportunity. An approach more in line with the evidence, and more likely to limit suffering, is to understand the damage that accumulates with age in the cerebral vasculature and therefore in the brain, and which eventually gives rise to cognitive symptoms in late life, too often leading to dementia. We argue that hope should be redirected to delaying that damage and with it the onset of cognitive loss; and, for each individual, it should be redirected to a life-long defense of their brain.
Hierarchical structure optimal setting approach for production indexes of the rolling heating furnace temperature field
Authors: Bao Qingfeng , Zhang Sen , Guo Jin , Ding Dawei , Zhang Zhenquan
Published: May 2023

In order to improve the optimal setting temperature problem to achieve the global optimum of product performance, costs and benefits. In this article, a hierarchical structure optimal setting approach of production indexes for the rolling heating furnace temperature field (RHFTF) is proposed. It is composed of three layers with different functions to obtain the temperature control setting model of the RHFTF. In the first layer, the bi-feature Gaussian mixture model clustering (BFGMMC) algorithm of loading plan is proposed to optimize the setting of a limited number of slabs. In the second layer, the type-2 fuzzy rule interpolation (T2FRI) setting method is developed to obtain the optimal setting curve. Meanwhile, an improved KH (Kóczy-Hirota) α-cut distance (IKHCD) algorithm is proposed to get the miss information between any two adjacent interpolation points. In the third layer, knowledge feedforward compensation of rule matrices (KFCRM) algorithm is presented to improve the anti-interference ability of the setting model. The results of the study can demonstrate that the proposed method improves the accuracy of the model and optimizes the control strategy. Furthermore, the experimental results show that the proposed method meets the process technical requirements.
Image stitching using sigmoid function to create perception mask
Authors: Ma Mingxi , Wang Jinliang
Published: May 2023

The point features of low-texture images are insufficient and unreliable, so it is difficult to achieve good alignment and easy to damage the image structure. To solve these problems, in this paper, we propose a new image stitching method by using the sigmoid function to create perception mask. Firstly, the point features and line features are used to improve the accuracy of image registration and the naturalness of distortion. Secondly, an energy function is used to optimize the alignment model. Finally, we propose to use sigmoid function to create perception mask image to reduce artifacts and retain image structure. The gradient domain fusion algorithm is combined to achieve image fusion. Experimental results are provided to demonstrate that the proposed method is superior to some previous methods in reducing artifacts and maintaining image structure.
Feature selection based on a multi-strategy African vulture optimization algorithm and its application in essay scoring
Authors: Qu Liangdong , Li Xiaoqin , Tan Mindong , Jia Yingjuan
Published: May 2023

Reducing the dimensions of the original data set while preserving the information as much as possible is conducive to improving the accuracy and efficiency of the model. To achieve this, this paper presents a multi-strategy African vulture optimization algorithm that is the chaotic and elite opposition-based African vulture optimization with the simplex method and differential evolution strategy(CESDAVO). Three main improvements are introduced into African vultures optimization(AVO) to improve its capabilities in this study. Firstly, the chaotic elite opposition-based learning strategy is used to initialize and diversify individual positions of vultures. Secondly, the simplex method is used to optimize those poor individuals so as to further improve the local exploitation ability of the algorithm. Thirdly, the differential evolution strategy is used to make the algorithm escape from the local optimum and improve the global optimization capability of the algorithm. The results of the ablation experiments show that mixing the three strategies greatly improves the optimization performance of the algorithm. In addition, Nine algorithms are compared with CESDAVO on 15 benchmark functions, and this experimental result shows that its optimization capability is superior to the others. Then, the proposed CESDAVO is employed for feature selection, and 12 standard datasets are used for experiments. According to the experimental results, CESDAVO obtained the highest average classification accuracy on 11 datasets and the highest feature selection rate on 8 datasets, which is significantly better than other algorithms. Finally, CESDAVO is also applied to feature reduction for essays, removing 24 features and significantly improving the classification accuracy on multiple classifiers.
The difference in the relationship of spinal sagittal alignment between individuals with flat lumbar and normal lordosis posture based on global and regional angles
Authors: Shin Sun-Shil , Yoo Won-Gyu
Published: May 2023

BACKGROUND: According to previous studies, the relationship between lumbar lordosis and thoracic kyphosis or that between pelvic parameters and thoracic kyphosis have been inconsistent. OBJECTIVE: The purpose of this study was to investigate spinal sagittal alignment and its relationship to global and regional lumbar and thoracic angles, pelvic and sway angles, and C7–S1 distance measurements, followed by a detailed subgroup analysis using an inertial measurement unit system. METHODS: A total of 51 asymptomatic volunteers stood in a comfortable posture with inertial measurement units attached to the T1, T7, T12, L3, and S2 vertebrae. T1, T7, T12, L3, and S2 sagittal angles were acquired during standing posture using the Eulerian angle coordinate system. All angles are reported as the mean of three 5-s measurements. Following the measurement of lumbar lordosis angles (T12 relative S2), participants were divided into the flat lumbar and normal lordosis groups. RESULTS: There were different correlation patterns between groups because of spinal sagittal imbalance, which was greater in the flat lumbar group than in the normal lordosis group. In addition, sacral inclination proved the ideal parameter to evaluate reciprocal balance in lumbar lordosis, showing a stronger correlation with lower than with upper lumbar lordosis. T1 was the key element in assessing thoracic kyphosis, which showed a stronger correlation with upper than with lower thoracic kyphosis. CONCLUSION: We suggest that when assessing posture, it is necessary to identify the global and regional angles and it is useful to classify spinal sagittal alignment into subgroups according to lumbar lordosis and evaluate the groups separately.
Comparison of parameter types for the calibration of noninvasive continuous cardiac output monitoring of patients undergoing lumbar spinal surgery in the prone position
Authors: Lee Seung Cheol , Lee Gang Hyun , Lee Tae Young , Park Sang Yoong
Published: May 2023

BACKGROUND: Cardiac output (CO) decreases on reversing the patient’s position to the prone position. Estimated continuous cardiac output (esCCO) systems can noninvasively and continuously monitor CO calibrated by patient information or transesophageal echocardiogram (TEE). OBJECTIVE: To compare the accuracy, precision, and trending ability of two calibration methods of CO estimation in patients in prone position. METHODS: The CO estimates calibrated by TEE (esT) and patient information (esP) of 26 participants were included. CO was collected at four time points. The accuracy and precision of agreement were evaluated using the Bland-Altman method. A four-quadrant plot was used for trending ability analysis. RESULTS: The bias between esP and TEE and between esT and TEE was 0.2594 L/min (95% limits of agreement (LoA): -1.8374 L/min to 2.3562 L/min) and 0.0337 L/min (95% LoA: -0.7381 L/min to 0.8055 L/min), respectively. A strong correlation was found between ΔesP and ΔTEE (p< 0.001, CCC = 0.700) and between ΔesT and ΔTEE (p< 0.001, CCC = 0.794). The concordance rates between ΔesP and ΔTEE and between ΔesT and ΔTEE were 91.9% and 97.1%, respectively. CONCLUSION: Despite limited accuracy and precision, esP showed acceptable trending ability. The trending ability of esCCO calibrated by the reference TEE value was comparable with that of TEE.
Serum tumor markers for response prediction and monitoring of advanced lung cancer: A review focusing on immunotherapy and targeted therapies
Authors: van den Heuvel Michel , Holdenrieder Stefan , Schuurbiers Milou , Cigoianu Daniel , Trulson Inga , van Rossum Huub , Lang David
Published: May 2023

BACKGROUND:

The value of serum tumor markers (STMs) in the current therapeutic landscape of lung cancer is unclear.

OBJECTIVE:

This scoping review gathered evidence of the predictive, prognostic, and monitoring value of STMs for patients with advanced lung cancer receiving immunotherapy (IT) or targeted therapy (TT).

METHODS:

Literature searches were conducted (cut-off: May 2022) using PubMed and Cochrane CENTRAL databases. Medical professionals advised on the search strategies.

RESULTS:

Study heterogeneity limited the evidence and inferences from the 36 publications reviewed. While increased baseline levels of serum cytokeratin 19 fragment antigen (CYFRA21-1) and carcinoembryonic antigen (CEA) may predict IT response, results for TT were less clear. For monitoring IT-treated patients, STM panels (including CYFRA21-1, CEA, and neuron-specific enolase) may surpass the power of single analyses to predict non-response. CYFRA21-1 measurement could aid in monitoring TT-treated patients, but the value of CEA in this context requires further investigation. Overall, baseline and dynamic changes in individual or combined STM levels have potential utility to predict treatment outcome and for monitoring of patients with advanced lung cancer.

CONCLUSIONS:

In advanced lung cancer, STMs provide additional relevant clinical information by predicting treatment outcome, but further standardization and validation is warranted.
Analysis of the mental health status of hospital staff during the COVID-19 pandemic
Authors: Zhang Yichi , Mo Qingqian , Tan Chen , Hu Jing , Zhao Min , Xiong Xiaoyun , Zhang Jinqiang
Published: May 2023

BACKGROUND: Medical work is a complex and interpersonally sensitive job; clinicians interact with patients, colleagues and society-at-large daily, and they are under pressure from a variety of sources. The doctor–patient relationship is of particular concern. OBJECTIVE: To investigate the current mental health status of hospital staff and related influencing factors during the coronavirus disease 2019 (COVID-19) pandemic. METHODS: The Symptom Checklist-90 (SCL-90) and Generalized Anxiety Disorder Scale-7 (GAD-7) were used to survey the current mental health status of hospital employees. The resulting qualitative data was described in the form of frequency and percentage (%), and the quantitative data were expressed as mean±standard deviation ( X ¯ ± S ). RESULTS: A total of 1,074 employees of The Third Xiangya Hospital of Central South University participated in the mental health survey, of whom 77.47% were women. The SCL-90 score was 133.89±48.87, and the three highest scoring factors were depression, somatisation and obsessions, with factor scores of 19.10±8.14, 16.78±6.21 and 16.27±6.39, respectively. The GAD-7 score was 3.74±4.17 for women and 2.14±3.55 for men. The number of women with anxiety disorders was higher compared with men. CONCLUSION: The mental health status of hospital workers with different demographic characteristics varied greatly during the COVID-19 pandemic. Active attention needs to be paid to the mental health status of hospital staff.
EFFECTIVENESS OF THERAPEUTIC TACTICS FOR ANALGESIA OF PATIENTS WITH GUNSHOT AND MINE-EXPLOSIVE WOUNDS AT THE STAGES OF TREATMENT
Authors: Kuchyn Iu.L. , Horoshko V.R.
Published: May 2023

Background. The effectiveness of the use of therapeutic tactics for pain relief at the stages of treatment is important considering the fact that chronic pain is diagnosed in 83.3% of patients with mine-explosive wounds, and in 70% of cases with gunshot wounds. In civilian life, among injured patients, this diagnosis occurs in 11-40% of cases. There is not enough data on the reasons for such a high frequency of chronicity. Thus, the study of the effectiveness of treatment tactics for pain relief in patients with gunshot and mine-explosive wounds at the stages of treatment will play an important role and contribute to improving the results of treatment of this category of patients.

Aim: To investigate the effectiveness of therapeutic tactics of analgesia in patients with gunshot and mine-explosive wounds at the stages of treatment.

Materials and methods. The treatment of 1166 patients with injuries was analyzed. Pain intensity was diagnosed using a visual analog scale. Group comparisons were performed using the Mann-Whitney test and the chi-square test with allowance for continuity correction, Kruskal-Wallis, and post hoc comparisons were performed using Dunn's test.

Results. In patients with gunshot wounds, during the analysis, it was found that VAS data significantly depend on the type of anesthesia. Using regional anesthesia, VAS data are the lowest at all measurement points (p<0.05). In patients who received landmine-explosive injuries, VAS data are weakly dependent on the choice of anesthetic support, however, this indicator still has higher values (p<0.05) when using general anesthesia. Two-factor analysis showed a relationship between the dynamics of VAS data and the type of injury (p<0.001), type of anesthesia (p<0.001).

Conclusion. Admission of a patient with a wound to a medical center with subsequent analgesia using regional anesthesia methods has the best outcome in terms of pain management and pain control in such patients.
CARDIOVASCULAR DISEASES AND OBSTRUCTIVE SLEEP APNEA SYNDROME. REVIEW
Authors: Mostbauer H.V. , Bezrodnyi A.B. , Rokyta O.I. , Moskalenko Y.M. , Shevchyk M.I.
Published: May 2023

Background.  Cardiovascular disease (CVD) is one of the main causes of morbidity and mortality among adults worldwide. On another hand, obstructive sleep apnea syndrome (OSAS) is common in patients with CVD, and can worsen the patients prognosis due to late diagnosis. 
Aim: to analyze and summarize the published researches about interrelation between CVD and OSAS, its influence on CVD, and the effects of continuous airway pressure (CPAP) treatment of OSAS on CVD in order to pay attention to OSAS potential risks, improve the investigation of this syndrome and management.
Materials and methods. Review of scientific literature in the international electronic scientometric databases PubMed, Google Scholar by key words for the period 2008-2023. The search was carried out by two independent authors. 150 sources were selected, 48 English–language articles of which met all the search criteria and  were used for analysis.
Results. OSAS is one of the widespread sleep disorders that frequently occurs in patients with CVD, impairs quality of life. Its increases cardiovascular and all-cause mortality and cardiovascular morbidity. OSAS is observed in patients with arterial hypertension in 30-83%, coronary heart disease in 38-65%, stroke in 57-65%, heart failure in 12-55%, heart rhythm disorders - in 20-50%. In addition, the relationship between OSAS and diabetes, metabolic syndrome, insulin resistance, depression, and cognitive impairment has been established. OSAS is often not diagnosed or not diagnosed in time. Thus, there are data that 86-95% OSAS, clinically manifestated, were  missed diagnosis, that  worsens the prognosis of such patients.
Conclusions. OSAS is a common sleep breathing disorder in patients with CVD that is often diagnosed late. Most studies have shown that OSAS worsens the CVD course and outcomes. Therefore early diagnosis and timely appropriate treatment reduce morbidity and mortality.
Survey of knowledge of the Andrenidae Family (Insecta: Hymenoptera)
Authors: Marchiori Carlos Henrique
Published: May 2023

They are typically solitary, so each female builds her own nest, consisting of one or a few cells at the end of a gallery, each cell presenting a clear bilateral symmetry. Some species can present a gregarious behavior, so they can be found forming aggregations of up to 40 females. Exceptionally, groups of up to 500 females have been found sharing a single entrance to the nest, a behavior that gives them an advantage over some parasites The family Andrenidae (Bulldozer bees) are not offensive, only when defending their eggs will they take the initiative to attack. Their claw needles are not powerful and usually cannot penetrate the skin. After being stabbed, they feel only mild pain. The female digs branching tunnels and forms a cell at the end of each one, where she deposits an egg after supplying it with pollen and nectar. The objective of this paper is to know the characteristics of the Family Adrenidae. In terms of the type of research source, we worked with scientific articles published in national and international journals. This modality of production, in addition to being commonly the most valued in the set of bibliographic production, is the most easily accessed. Access to articles was through virtual libraries such as SciELO, ResearchGate, Hall, USP, UNB, CAPES and LILACS.
Factors Affecting Traffic Noise and Annoyance from Different Types of Roads: A Case Study in Nakorn Pathom Province, Thailand
Authors:   Department of Environmental Health Sciences, Faculty of Public Health, Mahidol University, Bangkok, Thailand, Siwapathomchai Nattawat , Aimyong Natnaree ,   Department of Epidemiology, Faculty of Public Health, Mahidol University, Bangkok, Thailand, Patthanaissaranukool Withida ,   Department of Environmental Health Sciences, Faculty of Public Health, Mahidol University, Bangkok, Thailand, Sihabut Tanasri ,   Department of Environmental Health Sciences, Faculty of Public Health, Mahidol University, Bangkok, Thailand
Published: May 2023

This study investigated factors associated with road traffic noise and residents’ annoyance from three distinct types of roads (major arterial, minor arterial, and collector roads). Nine sampling locations in Thailand’s Nakorn Pathom Province were chosen for the measurement of noise levels and three contributing characteristics: traffic volume, vehicle speed, and the proportion of heavy to total vehicles. Along with a housing survey, face to face interviews with a total of 387 roadside dwellers recorded their sociodemographic data, activity-based locations, and noise impacts experienced. A statistical analysis based on Spearman correlation revealed a positive relationship between traffic volume and traffic noise level on major arterial (r=0.607) and collector roads (r=0.885). Residents around collector roads were more sensitive than those along the main arterial road, in spite of having lower noise levels and less intense traffic patterns. Longer housing setbacks appeared to be a key factor in reducing noise annoyance from all road types, according to an exact logistic regression analysis (OR=0.11, 95% CI: 0.003, 0.73 for the major arterial road; OR=0.29, 95% CI: 0.10, 0.78 for the minor arterial road; and OR=0.32, 95% CI: 0.12, 0.84 for collector roads). However, performing activities in closed areas (OR=0.05, 95% CI: 0.01, 0.17 for the minor arterial road; OR=0.22, 95% CI: 0.54, 0.90 for collector roads) and living in soundproof structures (OR=0.05, 95% CI: 0.001, 0.31 for collector roads) played additional roles to reduce the annoyance of residents along the roads with shorter setback lines.
Metaphors and Similes for Yahweh in Hosea 14:2-9 (1-8) : a Study of Hoseanic Pictorial Language
Authors:   ,   Andrews University, Oestreich Bernhard
Published: May 2023

Problem. Compared with the effort to interpret other parts of the book of Hosea, especially the first three chapters, the final chapter has been rather neglected. Additionally, the variety of explanations offered for certain biblical images in Hos 14 indicates a necessity to clarify the methods of interpretation of biblical metaphorical language. Method. Chapter 1 clarifies the theory of metaphors on which the study is based. Chapter 2 determines the limitation and the structure of the passage Hos 2:2-9 (Eng. 1-8). In chapters 3 to 6 the metaphors and similes of this passage which refer to Yahweh, i.e., "healing," "loving," "dew," and "tree," are investigated in turn. According to the results of modern linguistics, metaphors and similes are investigated as phenomena of language based on the Old Testament as their immediate cultural and linguistic context and, if necessary, on figurative speech of the ancient Near East. The language traditions of the metaphors are studied. On this background the actual usage in the book of Hosea with its twists, alterations, and reversals is interpreted. Results. The study demonstrates that Hosea's metaphors and similes are deeply rooted in Israelite language traditions. An interpretation based on mythology or cult practices, that understands the metaphors in some sense as a literal description of Hosea's or the people's experience, is rejected because it is not supported by the texts and because it implies a devaluation of the metaphors. The metaphoric language in Hos 14 suggests that there exists a covenant relationship between Yahweh and His people Israel. Moreover, all the metaphors for Yahweh are traditionally connected with kingship. However, they are used in such a way that they give expression to an eschatological hope with Yahweh as Israel's king. This hope, however, does not downgrade Yahweh's radical judgment. The use of similes and clusters of metaphors has a rational effect and demonstrates how the prophet argues with his audience. Conclusions. Biblical metaphors and similes must be interpreted on the background of their language conventions. The particular characteristic of the use of the metaphor becomes clear and can only be appreciated in comparison to its conventions. The study of convention and actual usage yields the appropriate interpretation.
Adapting Architectural Models for Visualization Using Virtual Reality Headsets
Authors:   ,   Andrews University, Martinez Bernardo
Published: May 2023

Business contracts represent a main source of income for Architects. Acquiring these contracts requires the latest and most immersive technology that improves their sales against competitors. Virtual reality provides an in-depth experience that allows clients to have a reasonable assurance that the building meets their physical expectations. Videos and photos are detached and mundane; while they provide some visual representation they will not allow the user to compare his physical characteristics (height, length, width) with a 3D model. In this paper, I describe a procedure for automatically importing 3D models from Revit into Unreal4. I also describe the workflow required which includes constraints and benefits found along the way. As my focus was based on VR, a lot of my work was around the Oculus VR headset which provides an immersive experience into future and current buildings. The software tools I wrote modify 3D models to be compliant with UE4 materials, textures, groupings and it allows developers to split buildings into multiple slices improving performance and polygon counts.
A Comparative Study of the Sabbath Theologies of A.H. Lewis and J.N. Andrews
Authors:   ,   Andrews University, Roeske Siegfried
Published: May 2023

Problem. Although Seventh Day Baptists and Seventh-day Adventists share a common heritage in the Sabbath doctrine, it has been recognized that significant differences in the Sabbath theologies of the denominations are distinguishable. However, literature that substantiates the nature of the differences in theology has not been researched and compared. The purpose of this study was primarily to investigate and compare differences in the theology of the two denominations as seen in the writings of representative theologians Seventh Day Baptist A. H. Lewis and Seventh-Adventist J. N. Andrews, and secondarily to consider how the differences may have affected the vitality of the respective denominations. Method. The writings of the two theologians were first presented using a thematic descriptive approach with attention given to development or growth of the theologies. Their views were then compared in significant areas, and effects of the theologies on the respective denominations compared. Results. The research ascertained that (1) there is a high degree of similarity in the biblical-historical material, but divergence in the philosophical and prophetic-eschatalogical perspectives of the two writers; (2) that the emphases of these theologians has significantly impacted the theologies of their respective denominations; and (3) that there is indication that the theologies of the denominations have affected the vitality of the movements.
The Presence of the Covenant Motif in Amos 1:2-2:16
Authors:   ,   Andrews University, Siqueira Reinaldo
Published: May 2023

The presence and use of the OT covenant(s) in the book of Amos has been a highly debated issue for the last century among OT scholars. The dissertation attempts to address this issue through an exegetical study of the "Oracles Against the Nations" of Amos 1:2-2:16. This pericope of Amos was chosen because it has played a central role in the argumentation that denies the existence of any notion of covenant in the book. Chapter 1 introduces the controversy that surrounds the issue of the presence or absence of covenant in Amos, while chapter 2 surveys the scholarly debate and the ideas advanced in the last hundred years. The exegetical study of Amos 1:2-2:16 begins in chapter 3. This literary pericope is situated within the historical and literary contexts of the book of Amos. These two contexts evidence a tension between salvation and judgment that points to the dimension of "blessings and curses" of the Mosaic covenant. The specific literary features of Amos 1:2-2:16 are examined inchapter 4. The first seven oracles of the series are seen to be typical oracles of judgment, while the oracle against Israel is a sweeping covenant lawsuit that undoubtedly points back to the Mosaic covenant. Chapter 5 analyzes the terminology and themes that are related to God, the prophet, and the nations in Amos 1:2-2:16. Elements of four OT covenants are evidenced through this analysis. God is YHWH- -the creator of the universe and Sovereign of the world (universal/Noahic covenant); Israel's covenant God (Abrahamic and Mosaic covenants); the One who dwells in Jerusalem (Davidic covenant). The prophet is YHWH's messenger and covenant mediator (Mosaic covenant). The foreign nations are judged for transgressions of universal laws of God (universal/Noahic covenant), while Judah and Israel are judged for transgressions of the Mosaic law (Mosaic covenant). The exegetical study of Amos 1:2-2:16 evidenced a substantial presence and use of the covenant motif in this series of oracles. Four OT covenants (universal/Noahic, Abrahamic, Mosaic, and Davidic) are interrelated in the series. The Davidic and Abrahamic covenants provide the general background of the oracles. The universal/Noahic and Mosaic covenants account for the specifics of each oracle.
Resurrection in Daniel 12 and its Contribution to the Theology of the Book of Daniel
Authors:   ,   Andrews University, Stele Artur
Published: May 2023

This study attempted to investigate the resurrection passages of Dan 12. The main concern was to discover the nature, scope, timing, and purpose of the resurrection in Dan 12:2 and 12:13, to establish the relationship between these two passages, and to determine the contribution of the resurrection of Dan 12 to the theology of the book of Daniel. Chapter 1 offers a review of literature that presents the different and often conflicting opinions regarding the kind, extent, timing, and function of the resurrection in Dan 12. Chapter 2 provides an exegetical study of the two resurrection passages in Dan 12 and determines their relationship insofar as they respond to the"what," "when," "who," and "why" of the resurrection. Chapter 3 investigates the relationship of the resurrection passages to other passages of the book of Daniel and explores the contribution of the resurrection theme of Dan 12 to the major theological themes of the book of Daniel. Finally, a summary, conclusions, and implications bring together the major findings of this research. Based on the evidence submitted in this dissertation, it is concluded that both resurrection texts in Dan 12 refer to a physical resurrection. However they refer to two different events. Dan 12:2 speaks of a partial resurrection at the end of time, while Dan 12:13 refers to the general resurrection at the end of the days, namely when the Kingdom of God will consume all the earthly kingdoms. The theological study of the resurrection revealed that the resurrection passages are related to other passages of the book of Daniel and that they play an important role in the theology of the book of Daniel. It became evident that resurrection has a multifunctional purpose, the most significant of which seems to be the demonstration of God's power, sovereignty, and glory, His rulership over history, and His Lordship over life and death. The presence of the motifs of death, resurrection, retribution, eternal life, and judgment in the resurrection passages and their connection and considerable contribution to such major theological themes as the power and absolute sovereignty ofGod, the Kingdom of God, judgment, creation, and theology of history- -all seem to support the suggestion that resurrection is indeed the theological climax of the book of Daniel.