bluuebunny/crossref_metadata_2025 huggingface dataset:
Actuales moléculas neuroprotectoras propuestas para el tratamiento de Evento Vascular Cerebral Isquémico
Authors: Miranda Mosqueda Martha Lisbeth , Flores Hernández KL , Méndez-Cuesta LA , Ruíz-Oropeza SY , Ventura-Martínez R , González-Barrios JA , Gómez Acevedo Claudia
Published: August 2023

La enfermedad vascular cerebral (EVC) es un síndrome clínico de desarrollo rápido cuyas consecuencias conforman la primera causa de discapacidad en adultos y la tercera causa de muerte a nivel mundial, representan un gran campo de investigación debido a las pocas estrategias terapéuticas clínicas existentes para el tratamiento de sus secuelas. En la actualidad diversas moléculas han sido probadas con el objetivo de localizar un potencial neuroprotector cuya utilización sea trasladable y efectiva en el campo clínico, esta búsqueda ha abarcado además de fármacos utilizados en otras patologías, fitofármacos que han demostrado tener efectos positivos interactuando con la cascada isquémica desatada después de un EVC. En esta revisión el objetivo fue recabar información acerca de algunas moléculas novedosas y de reportes recientes que representan un avance en el tratamiento de la EVC.
Práctica de Antiparasitarios como Estrategia Didáctica para Estudiantes de Farmacología de la Carrera de Médico Cirujano
Authors: Ángeles López Guadalupe Esther , Segovia Mendoza Mariana , Ventura-Martínez Rosa , Alpizar Márquez Alan Manuel , Martínez Luna Jesús Ernesto , Maldonado Sánchez Erasmo
Published: August 2023

La Farmacología es una de las asignaturas primordiales para los estudiantes de Medicina, que permite a los alumnos adquirir habilidades y conocimientos fundamentales para el uso racional de medicamentos. Las prácticas de laboratorio son estrategias didácticas que favorecen la integración de conocimientos, así como reflexión y razonamiento. Debido a que en el ciclo escolar 2021-2022 la asignatura de Farmacología de la Carrera de Médico Cirujano de la Facultad de Medicina de la UNAM no contaba con una práctica de laboratorio relacionada con el tema de antiparasitarios que completamentara al tema de Quimioterapia Infecciosa, el objetivo de este trabajo fue la creación y descripción de la misma. Para la creación de la práctica se utilizó eXe-Learnig, un programa que facilita de creación de contenidos educativos. A través de este programa se presentan 4 casos clínicos de infecciones producidas por Giardia lamblia, Trichomonas vaginalis, Ascaris lumbricoides y Plasmodium vivax. En la práctica se incluyó un video explicando definiciones y clasificación de parásitos. Cada caso clínico plantea diferentes preguntas acerca del ciclo de vida de cada microorganismo, los tratamientos farmacológicos con su mecanismo de acción, farmacocinética y efectos adversos de los antiparasitarios. Es importante mencionar que, la presente práctica se encuentra incorporada en el Programa Académico de la Asignatura de Farmacología en el aula virtual del Departamento de Farmacología. Además, la práctica ha presentado buena aceptación por parte de los alumnos y por esta razón es muy importante continuar con la creación de nuevas estrategias didácticas, como la implementación de prácticas digitales.
Effects of Governance Systems on Organizational Performance of Water Service Companies in Kenya
Authors: Nkonge Joslyn
Published: August 2023

Good Governance is a process whereby public and private institutions manage resources to promote development, human rights, justice, peace, accountability, responsiveness, inclusiveness, democracy, and adherence to the rule of law. However, there are many challenges in the governance systems, including politics, corruption, lack of transparency, and lack of accountability. This research focused on the governance systems of water sector companies in Kenya from 2002 to 2021. The purpose of this study was to determine the effects of governance systems on the organizational performance of water service companies in Kenya. The study was limited to 79 registered Water and Sanitation companies in Kenya and 47 Senior Executives in charge of water and sanitation in every county in Kenya, and the CEOs/Senior Executives of the two water regulatory bodies, Water Services Regulatory Board (WASREB) and Water Resources Management Authority (WRMA). The following theories were used; The Systems Theory, The Good Governance Theory and The Resource-Based View Theory. To determine the sample size, simple random sampling techniques were used. Self-administered questionnaires and interview guide questions were used to collect primary data.  A sample size of 281 respondents was used. The data was analysed using the Statistical Package for the Social Sciences (SPSS). Correlation and linear regression techniques were used to test the research hypotheses. The study found that water governance framework and performance had a statistically significant linear relationship (r= 0.524, p<.05). The study revealed that water framework variables account for 52.4% of the variability in the performance of water service companies in Kenya. The findings from the regression model indicated that the governance framework significantly influences the organisational performance of water service companies (β = 0.311, p<0.05).  The results of this study may be used by water service companies and County Governments in the formulation and implementation of strategies regarding water governance.
The Impact of Radon Gas on Pulmonary Cancer in Albania
Authors: Prifti Pirro , Shuperka Roland , Telo Sofiela
Published: August 2023

This Article shows real cases of patients with Pulmonary Cancer admitted and treated in the University Pulmonary Hospital of Tirana `Shefqet Ndroqi` during the three last years: 2013-2014-2015. All data are confirmed by the Statistics division of the University Pulmonary Hospital of Tirana `Shefqet Ndroqi`. All data are compared with international standard data of potential possibilities of causing Pulmonary Cancer by gas Radon, in the Albanian population during these three years of study to the smoking and non-smoking people. Is known the importance of gas Radon to cause of Pulmonary Cancer to the smoking and non –smoking people. As for internationally standard data, Pulmonary Cancer is caused by gas Radon in proportion of 3 people about 1.000 to the contingent to the smoking people, and in proportion of 0.7 people about 1.000 people to the contingent of non-smoking people. All data extracted from the statistics office of the University Pulmonary Hospital of Tirana `Shefqet Ndroqi` during the three last years: 2013-2014-201, are compared with 0.4 pCi/L(picocyri/liter) that is lowest level of gas Radon Concentration that can be potentially cause Pulmonary Cancer of 3/1000 to the smoking people and of 0.7/1000 non-smoking people This Article do presents differences about real patients with Pulmonary Cancer admitted and treated during years 2013-2014-2015 with Pulmonary Cancer can be caused theoretically in Albania population by Gas Radon to the smoking people and non smoking people.
Contribution of Medical Anthropology in the Treatment of Health Care
Authors: DHIMA Aleksandër
Published: August 2023

This study deals with the achievements of medical anthropology, as one of the subdivisions of Anthropology, little or not known until now in Albania. It relies, first of all, on the health culture of the peoples and their social construct in relation to health, which is dictated – among others- by cultural norms and local decisionmaking institutions. The article further discusses the connections of Anthropology with medical practice, the areas of application of medical anthropology and the current agenda of its action. The second part is dedicated to the Anthropology of COVID-19. According to the author, this new pandemic has hit human populations, perhaps like never before, at least in terms of the extent shown by previous models and forecasts, changing their environmental balance. It brings the personal experiences of 15 medical anthropologists, who have researched specific aspects of the pandemic in different areas of the globe. Their involvement in the analysis of the facts so far and in terms of the socio-cultural response of different population groups to it deserve special attention, as well as the interaction of emergencies involving universal health care, climate change and civil liberties.
Natural Birth After Cesarean Section
Authors: Ceni Nazmie , Ceni Renata , Bimbashi Astrit
Published: August 2023

Vaginal birth after cesarean section (VBAC) describes a vaginal delivery in a woman who has given birth via cesarean section in a former pregnancy. Patients desiring VBAC delivery undergo a trial of labor (TOL), also called trial of labor after cesarean section (TOLAC). While TOL is an accepted and generally safe practice, serious potential complications include uterine rupture or uterine dehiscence and associated maternal and/or neonatal morbidity. Providers caring for patients with prior cesarean section need to counsel patients regarding potential risks and benefits of TOL and the factors which affect the likelihood of successful vaginal delivery. These providers must be knowledgeable regarding intrapartum management of patients undergoing TOLAC and able to recognize and appropriately manage potential complications. This activity reviews the evaluation and management of patients undergoing vaginal birth after cesarean delivery and highlights the role of interprofessional team members in collaborating to provide well-coordinated care and enhance outcomes for affected patients.
Penghayatan Ratapan dalam Liturgi
Authors: Djuharto Ivana Aimee
Published: August 2023

Abstrak

Di dalam realita kehidupan manusia, tidak bisa dipungkiri orang Kristen pasti akan mengalami berbagai penderitaan. Hal ini menyebabkan orang Kristen kemudian berada dalam posisi dilema antara pengharapan yang ada di dalam ajaran Kristen dan realita kehidupan yang mengalami banyak penderitaan. Dalam hal ini, penulis menjelaskan bahwa ratapan dapat menjembatani dilema tersebut. Penulis akan menjelaskan hal terkait dengan menggunakan metode penelitian kepustakaan. Penulis di dalam penyajiannya akan membahas terlebih dahulu bahwa ratapan merupakan bagian yang diperlukan di dalam keutuhan manusia, kemudian memberikan penjelasan alkitabiah dari Perjanjian Lama, sosok Yesus, dan Perjanjian Baru sebagai landasan aspek ratapan. Beranjak dari situ, penulis kemudian menjelaskan pentingnya penghayatan ratapan di dalam liturgi dan memberikan contoh penyisipan ratapan dalam liturgi. Melalui tulisan ini, didapati bahwa ratapan adalah hal yang wajar yang manusia perlu lakukan; ratapan dapat menjembatani dilema pengharapan dan penderitaan yang dialami oleh orang Kristen sehingga perlu dilakukan salah satunya melalui liturgi.Kata kunci: ratapan; liturgi; pengharapan kristen; penderitaan manusia.
Propaganda Model Sinkretis Etis sebagai Budaya Tandingan terhadap Penistaan Agama di Media Sosial: Tinjauan Khusus Terhadap Kasus Joseph Paul Zhang
Authors: Saputra Jefri Andri
Published: August 2023

Kasus penistaan agama masih menjadi bagian dari konflik beragama di Indonesia. Media sosial memiliki peran yang sangat krusial dalam maraknya kasus ini. Selain melalui proses hukum, penyelesaian kasus ini masih berorientasi pada masing-masing agama. Oleh karena itu, penulis merekomendasikan propaganda kesadaran sinkretis-etis di media sosial sebagai budaya tandingan terhadap penistaan agama. Pendekatan yang digunakan dalam tulisan ini adalah budaya tandingan. Penulis menyimpulkan bahwa media sosial masih didominasi oleh konten yang bersifat destruktif terhadap agama. Oleh karena itu, kesadaran sinkretis etis perlu dipropagandakan sebagai konten yang konstruktif terhadap agama.
Memaknai Toleransi Secara Teologis Sebagai Upaya Moderasi Beragama
Authors: Henri Sirangki  , Payung Mariani Rombe , Yusri  , Allo Alfrisa Ayo’ Payung
Published: August 2023

Toleransi dan Moderasi adalah frasa yang menjadi atensi para peneliti sehingga banyak diantara  mereka menjadikannya sebagai topik tulisan. Kendati frasa ini bukan hal yang asing, namun implementasinya baik bersifat individu maupun komunal dalam kehidupan masyarakat majemuk masih sulit terejewantahkan. Karena itu, tujuan penelitian ini untuk menjelaskan bagaimana seyogianya hidup bertoleransi di tengah pluralisme agama sebagai upacaya moderasi beragama. Metode yang digunakan adalah kualitatif deskriptif di mana pengumpulan data melalui kepustakaan. Hasil yang dicapai dipaparkan dalam bentuk naratif yang bersifat deskriptif. Toleransi adalah sikap terbuka dan menerima dengan tulus hati perbedaan yang ada. Sementara moderasi beragama adalah sikap moderat yang menjadi acuan dalam beragama. Perjanjian Lama menjelaskan bahwa sejak mulanya Allah menciptakan perbedaan. Kehidupan nenek moyang bangsa Israel yang hidup di tengah bangsa asing adalah bukti bahwa kehidupan manusia pada mulanya telah hidup dalam perbedaan. Kehidupan mereka di tengah pluralisme bangsa dan agama bukan menimbulkan kerenggangan, melainkan menjadi berkat bagi mereka bahkam telah menjadi bangsa yang besar. Perjanjian Baru mencatat bagaimana seyogianya hidup toleran dalam masyarakat majemuk, bahkan Yesus sendiri menjadi pelaku toleransi dan memoderasi sikap radikal oleh agamaYudaisme yang ekstrem. Jadi secara teologis, ditemukan makna toleransi bahwa sejak mulanya perbedaan itu ada, Dalam upaya moderasi beragama, maka mesti ada saling menghargai antar sesama pemeluk agama, sehingga kerukunan tetap tercipta.
ABAH GURU SEKUMPUL
Authors: Lantigimo Enta Malasinta , Ripaldi  , Afriliani Lia
Published: August 2023

Pemajangan gambar ulama di dinding unit usaha, secara khusus gambar Abah Guru Sekumpul merupakan tradisi umat Islam di Banjarmasin, tujuannya utamanya adalah berhubungan dengan spiritualitas keislaman, di antaranya untuk keberkahan dalam berusaha sekaligus penghormatan kepada para Hamba Allah. Menarik, walaupun pelaku pemajangan gambar adalah Umat Islam, namun dampak positifnya sangat terasa dalam kehidupan sosial masyarakat secara umum. Berdasarkan hasil penelitan, ditemukan data bahwa para pelaku dagang dari berbagai kalangan dan latar belakang agama yang beragam akan sangat menikmati transaksi usaha yang jujur dan saling menguntungkan yang dilandasi pada keyakinan bahwa pemajangan gambar ulama sebagai simbol kebaikan dalam berusaha. Keadaan ini akan sangat berpengaruh dalam relasi sosial, sebab akan menumbuhkan rasa saling membutuhkan dan rasa saling percaya yang berujung pada sebuah relasi yang damai, rukun dan nyaman dalam kehidupan masyarakat.
PENCEGAHAN KEKERASAN SEKSUAL PADA ANAK PAUD MELALUI MEDIA EDUKASI VIDEO
Authors: Revine Siahaan Edita , Nuriman Arif
Published: August 2023

Pencegahan  kekerasan seksual pada anak usia dini sangat penting ,dikarenakan kondisi yang terus meningkat setiap tahunnya. Data Sistem Informasi Online Perlindungan Perempuan dan Anak (SIMFONI PPA) per tahun 2023 terdapat 9.644 kasus Pendidikasn seksual pada usia dini sangat penting seperti video edukasi, gambar edukasi dan support guru serta orangtua. Lokasi pengabdian ini di PAUD Al Bara Bandar Lampung. Pengetahuan anak meningkat secara sgnifikan setelah diberikan edukasi.
Kata Kunci:  Pencegahan, Kekerasan, Seksual dan Anak
 
                                                                         ABSTRACT
.
Prevention  of sexual violence in early childhood is very important, because conditions continue to increase every year.Data from the online information system for the protection of women and children ( SIMFONI PPA) in 2023 there werw 9.644 cases. Sexual education at an early age is very important, such as educational videos, educational pictures and support for teachers and  pictures and parents. The location of this service is PAUD Al Bara Bandar Lampung. Childrens knowledge increases significantly after being given education.
 
Keywords:  Prevention, Violence, Sexual and  Children.
EXPERIMENTAL PERFORMANCE EVALUATION OF A CHARCOAL-FIRED FISH SMOKING KILN
Authors: Sintali I. S. , Abioye A. M. , Shuaibu I.
Published: August 2023

Efficient fish preservation is important when quality, hygienic products and the highest possible profits are to be achieved in fish production. An effective-fired charcoal-fired fish smoking machine was designed and developed with a carrying capacity of 7.2 kg in which the smoking of fish was carried out. The temperatures of the air within the smoking chamber were raised to the smoking temperatures (343.15K, 363.15K and 383.15 K) at varying velocities of air and maintained for some time until the moisture contents of the fish were reduced to between 16 - 18%. The temperature of the air increased steadily until the smoking temperatures were achieved and these occurred between 20 – 27 min. The time taken for the fish to attain the smoking temperature was recorded to be between 120 – 160 min. The minimum time taken for expelling the moisture content was 155 min at a drying temperature of 383.15 K and velocity of 1.0 m/s and the maximum time was 225 min at a drying temperature of 343.15 K and velocity of 0.6 m/s. The computed fish drying rate was 𝑅𝑐 = 0.005370(%/𝑠) hence, for effective fish smoking, the fish should be smoked at a temperature and velocity of 383.15 K and 1.0 m/s respectively at a drying rate of 𝑅𝑐 = 0.005370(%/𝑠).
Geometric Brownian Motion in Analyzing Seasonality of Gold Derivative Prices
Authors: Germansah Germansah , Tjahjana R. H. , Herdiana Ratna
Published: August 2023

Complex financial markets, influenced by complex and interconnected factors, require proper decision making. Gold derivatives, as an increasingly popular trading instrument, have experienced significant growth. However, with high profit potential also comes significant risk. Market analysis, including technical analysis and leveraging seasonality, can be an important tool in reducing risk and making smart decisions. This research aims to assess the effectiveness of the Geometric Brownian Motion (GBM) model in predicting Gold Derivative prices through the application of the Mean Absolute Percentage Error (MAPE) test.In this study, the Brownian Motion Geometric Method and Simple Moving Average are combined to analyze the seasonality of gold derivative prices to provide a view of price movement patterns. The results showed that the Brownian Motion Geometric Method was effective in predicting the price of gold derivatives, with a low error rate. In addition, seasonality analysis reveals monthly price movement patterns that can be a guide for traders and investors. This research provides valuable insights for decision making in gold derivatives trading in dynamic and complex financial markets.
The Soft Bulletin: PDF organisation
Authors: Royle Stephen
Published: August 2023

I recently asked on Twitter for any recommendations for software to organise my PDFs. I got several replies, but nothing really fitted the bill. This is a brief summary. My situation I have quite a lot of books, textbooks, cheat sheets, manuals, protocols etc. in PDF format and I need a way to organise them.
Realm of Chaos
Authors: Royle Stephen
Published: August 2023

Caution: this post is for nerds only. I watched this numberphile video last night and was fascinated by the point pattern that was created in it. I thought I would quickly program my own version to recreate it and then look at patterns made by more points. I didn’t realise until afterwards that there is actually a web version of the program used in the video here. It is a bit limited though so my code was still worthwhile.
Come To California
Authors: Royle Stephen
Published: August 2023

I’ve returned from the American Society for Cell Biology 2016 meeting in San Francisco. Despite being a cell biologist and people from my lab attending this meeting numerous times, this was my first ASCB meeting. The conference was amazing, so much excellent science and so many opportunities to meet up with people.
Super Automatic: computer-based tools for research
Authors: Royle Stephen
Published: August 2023

Since I have now written several posts on this. I thought I would summarise the computer-based tools that we are using in the lab to automate our work and organise ourselves.
Colours Running Out: Analysis of 2016 running
Authors: Royle Stephen
Published: August 2023

Towards the end of 2015, I started distance running. I thought it’d be fun to look at the frequency of my runs over the course of 2016. Most of my runs were recorded with a GPS watch. I log my cycling data using Rubitrack, so I just added my running data to this. This software is great but to do any serious number crunching, other software is needed.
For What It’s Worth: Influence of our papers on our papers
Authors: Royle Stephen
Published: August 2023

This post is about a citation analysis that didn’t quite work out. I liked this blackboard project by Manuel Théry looking at the influence of each paper authored by David Pellman’s lab on the future directions of the Pellman lab. It reminds me that papers can have impact in the field while others might be influential to the group itself.
Inspiration Information: some book recommendations for kids
Authors: Royle Stephen
Published: August 2023

As with children’s toys and clothes, books aimed at children tend to be targeted in a gender-stereotyped way. This is a bit depressing. While books about princesses can be inspirational to young girls – if the protagonist decides to give it all up and have a career as a medic instead (the plot to Zog by Julia Donaldson) – mostly they are not.
Meeting in the Aisle
Authors: Royle Stephen
Published: August 2023

Lab meetings: love them or loathe them, they’re an important part of lab-life. There’s many different formats and ways to do a lab meeting. Sometimes it feels like we’ve tried them all! I’m going to describe our current format and then discuss some other things to try. Our current lab meeting format is: Weekly. For one hour (Wednesdays at 9am) One person each week talks about their progress. It rotates around.
Cloud Eleven: A cloud-based code sharing solution for IgorPro
Authors: Royle Stephen
Published: August 2023

This post is something of a “how to” guide. The problem is how can you share code with a small team and keep it up-to-date? For ImageJ, the solution is simple. You can make an ImageJ update site and then push any updated code to the user when they startup ImageJ. For IgorPro, there is no equivalent. Typically I send ipf files to someone and they run the code, but I have to resend them whenever there’s an update.
Some Things Last A Long Time II
Authors: Royle Stephen
Published: August 2023

Back in 2014, I posted an analysis of the time my lab takes to publish our work. This post is very popular. Probably because it looks at the total time it takes us to publish our work. It was time for an update. Here is the latest version. The colours have changed a bit but again the graphic shows that the journey to publication in four “eras”: Pre-time (before 0 on the x-axis): this is the time from first submission to the first journal.
Installing open source PyMol on a Mac
Authors: Royle Stephen
Published: August 2023

This is a quick “how to” post. There is a licensed version of PyMol (MacPyMol) available, but the open source version can be installed on a Mac free of charge. The official page has a guide, which is not terribly detailed, and I found this excellent guide which is unfortunately out-of-date.
Blind To The Truth
Authors: Royle Stephen
Published: August 2023

Molecular Biology of The Cell, the official journal of the American Society for Cell Biology, recently joined a number of other periodicals in issuing guidelines for manuscripts, concerning statistics and reproducibility.
Tips from the blog XI: Overleaf
Authors: Royle Stephen
Published: August 2023

I was recently an external examiner for a PhD viva in Cambridge. As we were wrapping up, I asked “if you were to do it all again, what would you do differently?”. It’s one of my stock questions and normally the candidate says “oh I’d do it so much quicker!” or something similar. However, this time I got a surprise. “I would write my thesis in LaTeX!”, was the reply. As a recent convert to LaTeX I could see where she was coming from.
What Can You See?
Authors: Royle Stephen
Published: August 2023

Yesterday I tried a gedankenexperiment via Twitter, and asked: If you could visualise a protein relative to an intracellular structure/organelle at ~5 nm resolution, which one would you pick and why? https://twitter.com/clathrin/status/707949738323218432 I got some interesting replies: Myosin Va and cargo on actin filaments in melanocytes – Cleidson Alves @cleidson_alves COPII components relative to ER and Golgi for export of
Til I Die: Seeking new music
Authors: Royle Stephen
Published: August 2023

I’ve been following the tweets from an account called Albums You Must Hear @Albums2Hear. Each tweet is an album recommended by the account owner. I’m a sucker for lists of Albums That I Must Hear Before I Die since I’m always interested in new (or not so new) music recommendations.
Voice Your Opinion: Editors shopping for preprints is the future
Authors: Royle Stephen
Published: August 2023

Today I saw a tweet from Manuel Théry (an Associate Ed at Mol Biol Cell). Which said that he heard that the Editor-in-Chief of MBoC, David Drubin shops for interesting preprints on bioRxiv to encourage the authors to submit to MBoC.
Rollercoaster: ups and downs of Google Scholar citations
Authors: Royle Stephen
Published: August 2023

In the UK there is an advertising disclaimer that “the value of your investments may go down as well as up.” Since papers are our main commodity in science and citations are something of a return, surely the “value” of a published paper only ever increases over time. Doesn’t it? I think this is true when citations to a paper are tracked at a conventional database (Web of Science for example). Citations are added and very rarely taken away.
My Blank Pages V: Raw Data
Authors: Royle Stephen
Published: August 2023

Raw Data: A novel on Life in Science by Pernille Rørth (Springer, 2016) I was keen to read this “lab lit” novel written by renowned cell biologist Pernille Rørth. I’d seen lots of enthusiastic comments about the book, and it didn’t disappoint.
Esoteric Circle
Authors: Royle Stephen
Published: August 2023

Many projects in the lab involve quantifying circular objects. Microtubules, vesicles and so on are approximately circular in cross section. This quick post is about how to find the diameter of these objects using a computer. So how do you measure the diameter of an object that is approximately circular? Well, if it was circular you would measure the distance from one edge to the other, crossing the centre of the object.
New Lexicon: how to add a custom minted lexer in Overleaf
Authors: Royle Stephen
Published: August 2023

This quick post comes courtesy of LianTze Lim (an Overleaf TeXpert) and Kota Miura (a bioimage analyst). I asked on the ImageJ forum some time ago how to add an ImageJ Macro lexer for a LaTeX document I was writing. Kota responded with this lexer for pygments. I then asked Overleaf if it was possible to add a custom lexer to an Overleaf document using the minted package. At the time this was not possible.
The Digital Cell: Statistical tests
Authors: Royle Stephen
Published: August 2023

Statistical hypothesis testing, commonly referred to as “statistics”, is a topic of consternation among cell biologists. This is a short practical guide I put together for my lab. Hopefully it will be useful to others. Note that statistical hypothesis testing is a huge topic and one post cannot hope to cover everything that you need to know.
Methods papers for MD997
Authors: Royle Stephen
Published: August 2023

I am now running a new module for masters students, MD997. The aim is to introduce the class to a range of advanced research methods and to get them to think about how to formulate their own research question(s). The module is built around a paper which is allocated in the first session. I had to come up with a list of methods-type papers, which I am posting below. There are 16 students and I picked 23 papers.
The Digital Cell: Workflow
Authors: Royle Stephen
Published: August 2023

The future of cell biology, even for small labs, is quantitative and computational. What does this mean and what should it look like? My group is not there yet, but in this post I’ll describe where we are heading. The graphic below shows my current view of the ideal workflow for my lab. The graphic is pretty self-explanatory, but to walk you through: A lab member sets up a microscopy experiment.
Repeat Failure: Crewe Alexandra F.C.
Authors: Royle Stephen
Published: August 2023

Well, the 2015/2016 season was one to forget for Crewe Alexandra. Relegation to League Two (English football’s 4th tier) was confirmed on 9th April with a 3-0 defeat to local rivals Port Vale. Painful. Maybe Repeat Failure is a bit strong. Under Dario Gradi, the Railwaymen eventually broke into League One/Championship (the 2nd Tier) where they punched above their weight for 8 seasons.
The Digital Cell: Getting started with IgorPRO
Authors: Royle Stephen
Published: August 2023

This post follows on from “Getting Started“. In the lab we use IgorPRO for pretty much everything. We have many analysis routines that run in Igor, we have scripts for processing microscope metadata etc, and we use it for generating all figures for our papers. Even so, people in the lab engage with it to varying extents. The main battle is that the use of Excel is pretty ubiquitous.
Everything In Its Right Place
Authors: Royle Stephen
Published: August 2023

Something that has driven me nuts for a while is the bug in FIJI/ImageJ when making montages of image stacks. This post is about a solution to this problem. What’s a montage? You have a stack of images and you want to array them in m rows by n columns. This is useful for showing a gallery of each frame in a movie or to separate the channels in a multichannel image.
Rollercoaster II: more on Google Scholar citations
Authors: Royle Stephen
Published: August 2023

I’ve previously written about Google Scholar. Its usefulness and its instability. I just read a post by Jon Tennant on how to harvest Google Scholar data in R and I thought I would use his code as the basis to generate some nice plots based on Google Scholar data. A script for R is below and can be found here. Graphics are base R but do the job. First of all I took it for a spin on my own data.
Elevation: accuracy of a Garmin Edge 800 GPS device
Authors: Royle Stephen
Published: August 2023

I use a Garmin 800 GPS device to log my cycling activity. including my commutes. Since I have now built up nearly 4 years of cycling the same route, I had a good dataset to look at how accurate the device is. I wrote some code to import all of the rides tagged with commute in rubiTrack 4 Pro (technical details are below). These tracks needed categorising so that they could be compared.
Ten Years Gone
Authors: Royle Stephen
Published: August 2023

Ten years ago today I became a PI. Well, that’s not quite true. On that day, I took up my appointment as a Lecturer at University of Liverpool, but technically I was not a PI. I had no lab space (it was under construction), I had no people, and I also had no money for research. I arrived for work.
The Arcane Model
Authors: Royle Stephen
Published: August 2023

I’m currently writing two manuscripts that each have a substantial data modelling component. Some of our previous papers have included computer code, but it was straightforward enough to have the code as a supplementary file or in a GitHub repo and leave it at that. Now with more substantial computation in the manuscript, I was wondering how best to describe it. How much detail is required?
Pledging My Time II
Authors: Royle Stephen
Published: August 2023

2016 was the 400 year anniversary of William Shakespeare’s death. Stratford-upon-Avon Rotary Club held the Shakespeare Marathon on the same weekend. Runners had an option of half or full marathon. There were apparently 3.5 K runners. Only 700 of whom were doing the full marathon. The chip results were uploaded last night and can be found here. Similar to my post on the Coventry Half Marathon, I thought I’d quickly analyse the data.
In a Word: LaTeX to Word and vice versa
Authors: Royle Stephen
Published: August 2023

Here’s a quick tech tip. We’ve been writing papers in TeX recently, using Overleaf as a way to write collaboratively. This works great but sometimes, a Word file is required by the publisher. So how do you convert from one to the other quickly and with the least hassle? If you Google this question (as I did), you will find a number of suggestions which vary in the amount of effort required. Methods include latex2rtf or pandoc.
Five Get Over Excited: Academic papers that cite quantixed posts
Authors: Royle Stephen
Published: August 2023

Anyone that maintains a website is happy that people out there are interested enough to visit. Web traffic is one thing, but I take greatest pleasure in seeing quantixed posts being cited in academic papers. I love the fact that some posts on here have been cited in the literature more than some of my actual papers. It’s difficult to track citations to web resources.
Do It Yourself: Lab Notebook Archiving Project
Authors: Royle Stephen
Published: August 2023

A while back, the lab moved to an electronic lab notebook (details here and here). One of the drivers for this move was the huge number of hard copy lab note books that had accumulated in the lab over >10 years. Switching to an ELN solved this problem for the future, but didn’t make the old lab note books disappear. So the next step was to archive them and free up some space.
Adventures in code
Authors: Royle Stephen
Published: August 2023

An occasional series in esoteric programming issues. As part of a larger analysis project I needed to implement a short program to determine the closest distance of two line segments in 3D space. This will be used to sort out which segments to compare… like I say, part of a bigger project. The best method to do this is to find the closest distance one segment is to the other when the other one is represented as an infinite line.
Paintball’s Coming Home: generating Damien Hirst spot paintings
Authors: Royle Stephen
Published: August 2023

A few days ago, I read an article about Damien Hirst’s new spot paintings. I’d forgotten how regular the spots were in the original spot paintings from the 1990s (examples are on his page here). It made me think that these paintings could be randomly generated and so I wrote a quick piece of code to do this (HirstGenerator). I used Hirst’s painting ‘Abalone Acetone Powder’ (1991), which is shown on this page as photographed by Alex Hartley.
Scoop: some practical advice
Authors: Royle Stephen
Published: August 2023

So quantixed occasionally gets correspondence from other researchers asking for advice. A recent email came from someone who had been “scooped”. What should they do? Before we get into this topic we have to define what we mean by being scooped. In the most straightforward sense being scooped means that an article appeared online before you managed to get your article online.
The eurocodes - research and application for concrete structures in Vietnam context
Authors: Nguyen Truong Thang , Nguyen Tuan Trung , Dang Viet Hung
Published: August 2023

Since 2018, it has been planned by the Vietnamese authorities for the preparation of a new system of the national construction codes and standards, of which the Eurocodes were recently taken into consideration to be systematically and gradually applied during the period from 2022 to 2030. Towards this orientation, significant attentions have also been paid and various number of studies on design of concrete structures to the Eurocodes have been conducted by Vietnamese researchers, which will be introduced in this paper to prepare for the comprehensive applications of the Eurocodes for concrete structures in Vietnam in the coming time when appropriable, especially the second generation of the Eurocodes will be expected to be also issued in coming years.
Ứng dụng mô hình nền hardening soil và mohr coulomb trong plaxis 3D mô phỏng tính toán chuyển vị tường vây
Authors: Nguyễn Ngọc Thắng , Thịnh Văn Thanh
Published: August 2023

Diaphragm wall deflection is considered one of the reasons for soil instability around excavation, causing serious consequences for neighboring constructions. Therefore, in the design and calculation of deep excavation, analyzing and simulating the diaphragm wall deflection between phases of excavation construction becomes very important. However, selecting an appropriate mathematical model and determining its input parameters affect the accuracy of the calculation results and their deviation from reality. In this article, the Hardening Soil (HS) model and the Mohr Coulomb (MC) model were used to simulate deflection calculations of diaphragm wall using Plaxis 3D and compared with data obtained from a real project in Ho Chi Minh City. The results showed that the stiffness parameter Eref50 was taken according to the formula Eref50 = 1000N for sandy soil (N: number of SPT blows), Eref50 = 500Su for cohesive soil (Su: undrained soil resistance) in the HS model, resulting in analysis of deflection that was quite compatible with actual data. In addition, the deflection of diaphragm wall varied inversely with its thickness, but this change was relatively small.
Ineficiencia del gasto público en zonas rezagadas del Perú periodo 2020-2023
Authors: Bayona López Fiorella Ivone
Published: August 2023

La investigación fue un estudio de caso de tipo cualitativo, nivel descriptivo y diseño transversal, el objetivo fue determinar la ineficiencia del gasto público en zonas rezagadas del Perú en el periodo 2020 al 2023; la hipótesis señaló que sí existe ineficiencia del gasto público en zonas rezagadas del Perú en el periodo 2020 al 2023; para la recolección de datos se utilizó la observación y el análisis de contenido. Los resultados revelan que de acuerdo con el Portal Transparencia Económica del MEF, solo se ha ejecutado un 48.6% del total del dinero que poseen los gobiernos regionales, siendo así, Huánuco es la región que ocupa el último lugar en ejecución de gasto público y solo ha gastado el 17.3%.
Pelatihan Pembuatan Rencana Bisnis bagi Koperasi Mitra Anuek Laot Lhok Lamteungoh Kabupaten Aceh Besar
Authors: Susanti  , Amri Saiful , Sarboini  , Yeni Manovri , Damayanti Ira , Agustiar
Published: August 2023

This training aims to increase the understanding of cooperative members in designing an effective Business Plan. This training includes developing a Business Plan, facilitating ideas and concepts, as well as drafting a Business Plan for cooperatives. The method applied in this activity is the participatory method, which is an effective learning approach by involving the activities of participants in the process of planning, implementing, and evaluating. The results of this training can be seen from the increased knowledge and involvement of participants in learning. The three types of businesses chosen by the participants as the focus of the SWOT analysis and Business Plan design were fish and octopus marketing, fishing gear marketing, and tourism businesses. The draft Business Plan resulting from this training will become the basis for developing a more comprehensive Business Plan, which will be implemented in stages. This draft will be used as a guide in cooperative member meetings to direct the steps for the next Community Service program.
Pemberdayaan Karang Taruna: Budidaya Ikan Lele Cegah Putus Sekolah di Desa Sidomulyo
Authors: Nugroho Wawan Sadtyo , Affan Nurifky Muhammad , Lestari Pipit Puji , Arifin Muhammad , Restiyono Nurwidya
Published: August 2023

Jetis Hamlet is part of Sidomulyo Village in Secang District, Magelang Regency. In this hamlet, many school-aged children are involved in agricultural and construction work. Previously, the Karang Taruna youth organization in Jetis Hamlet had started a catfish farming business. However, in the last two years, this business has experienced problems due to fish disease. The purpose of this activity is to motivate partners to increase their understanding of catfish farming, increase awareness of the problem of school dropouts, and reduce poverty levels. The results of this activity show that the establishment of this empowerment program has succeeded in overcoming problems in the catfish farming group. Through consistent guidance at various stages of the project and support for start-ups, the program has been successful in restoring and growing catfish farming businesses collectively.
Penyuluhan Kesehatan tentang Perubahan Fisiologis pada Ibu Hamil di Wilayah Kerja Puskesmas Watopute
Authors: Sugarni Mika , Sumi Susi Sastika , Yusnaeni Y  , Jamaluddin Maryam
Published: August 2023

Pregnancy is a natural process that causes a series of physiological changes in pregnant women. The physiological changes experienced during pregnancy sometimes become a period of vulnerability that requires special attention and vigilance. So that pregnant women need more knowledge about the many changes that can occur to their bodies. The purpose of implementing this community service activity is to provide additional knowledge about physiological changes both physically and organ systems in the body of pregnant women during pregnancy. The approach taken by the team was in the form of health education activities regarding physiological changes in pregnant women which were carried out offline through direct visits to Posyandu. As a result of community service activities, pregnant women feel very helpful because the discomfort that occurs during pregnancy is normal so that mothers do not need to feel anxious and worried.
Pendampingan Implementasi Digital Marketing Sebagai Strategi Pemasaran UMKM Sentra Tape di Desa Tegalwaru Kabupaten Jember
Authors: Sayekti Yosefa , Purnamawati Indah , Irmadariyani Ririn , Irawan Bambang , Agustini Aisa Tri
Published: August 2023

Partner of this Community Service Activity are are Micro, Small and Medium Enterprises (MSMEs) engaged in Snack/food manufacturing, namely tape (fermented cassava) located in Tegalwaru Village, Mayang District, Jember Regency. There are 10 MSMEs partners whose businesses have been established for a long time. However, the marketing activities are still traditional. For this reason, these MSMEs need to be given development related to their marketing and given training on the importance of digital marketing as a marketing strategy for MSMEs so that the marketing system is even better so that it can expand the scope of its target market and can increase sales. One of the digital media used to market products is Instagram. In addition, MSMEs are also given assistance in updating their product packaging to make it look more attractive so that it can attract consumer interest. The outputs resulting from this service activity are re-branding packaging, as well as maximizing the use of Instagram social media. The method used is to provide materials and training in the form of Focus Group Discussions (FGD). From the results obtained in this activity, it is suggested that the use of digital marketing should be more optimized so that it can produce the desired target, namely increasing market share and sales of MSMEs.
Pemberdayaan Masyarakat Oleh Mahasiswa Melalui Budidaya Dan Pelatihan Pengolahan Tanaman Obat Keluarga (TOGA) Dengan Memanfaatkan Lahan Perkarangan Menuju Keluarga Sehat Di Gampong Lam Bheu Kabupaten Aceh Besar
Authors: Mujiburrahmad  , Kesumawati Elly , Fitri Sri
Published: August 2023

Most of the houses owned by the community in Gampong Lam Bheu have yards and have not been used. The main problems of partners are: (1) Lack of knowledge and skills in TOGA cultivation starting from land preparation, seeding, planting and care. (2) Do not know what types of plants are included in TOGA (3). Lack of knowledge and skills in processing TOGA into herbs and other herbal medicines. (4). There is no village-owned TOGA educational park yet. Implementation activities will begin with the coordination and socialization stage, then continue with counseling on the introduction of types, benefits of family medicinal plants and making brochures. The next activity was a demonstration of the use of yards, proper cultivation of plants starting from cultivating the land, seeding, planting and maintenance, production of liquid organic fertilizers with household waste as raw materials and production of vegetable pesticides. Followed by a demonstration of the processing of TOGA into herbal medicine and herbal medicines, partners will then be facilitated in making the Village's Educational Park. Conclusion This PMM activity program is proven to have: Increased knowledge, skills and ability to understand the types and benefits of family medicinal plants, ability to understand TOGA cultivation, production of liquid organic fertilizer, and production of vegetable pesticides, as well as ability to process family medicinal plants into herbs and medicines herbal medicines that have high selling value
Peningkatan Kualitas Produk Paguyuban Jamu Manunggal Kota Cimahi Melalui Standardisasi Bahan Baku
Authors: Faramayuda Fahrauk , Windyaswari Ari Sri , Ilyas Ridwan , Wibiksana Dhimas Ariya , Ismail Nursafira Khairunnisa , Deris Reyhan Adriana , Sukma Rifaz Muhammad , Akbar Tzazkia Febriyana , Hafizah Chandani Nurul , Guntina Rizka Khoirunnisa
Published: August 2023

The activity of the community of herbal medicine manunggal in Cimahi city, as the main partner, is to guide the processing of traditional medicines and the herbal medicine business. The proposing team held an initial meeting and socialization for members of the Jamu Manunggal community in the city of Cimahi on December 25, 2021, regarding counseling on planting, post-harvest processing, and the benefits of the cat's whiskers plant. From the results of these activities, several problems were identified: the raw materials for traditional medicines in the Jamu Manunggal Association needed to be better standardized. This activity aims to improve the quality of traditional medicinal products through standardization. The results of the drying shrinkage testing of the five medicinal raw materials met the standards in the Indonesian Herbal Pharmacopoeia. In testing the water-soluble ash content, the levels obtained were not too large illustrating the potential for minor contamination of traditional medicinal raw materials. The general conclusion is that the raw materials for traditional medicine in the Jamu Manunggal Association of Cimahi City have good quality.
GANGGUAN IDENTITAS DISOSIATIF ANTAGONIS DALAM NOVEL TEROR KARYA LEXIE XU: KAJIAN PSIKOANALISIS SOSIAL KAREN HORNEY
Authors: Firmananda Zulvanny Fatma , H. Panam Rosman , Puspita Alvi
Published: August 2023

This study aims to identify the Neurotic Needs, Neurotic Trends, and Dissociative Identity Disorder of character Johan in Lexie Xu's Terror. This study used a descriptive-analytical method through a literary psychology approach, using the Social Psychoanalysis theory by Karen Horney. The findings are that Johan character has five out of ten forms of Neurotic Needs: influential partner, power, taking advantage of others, social respect or prestige, and personal admiration. Character Johan has a Neurotic Trends: against others, and seven out of ten symptoms Dissociative Identity Disorder: occasionally not aware of his actions, has deeply traumatization, often paranoid, has fluctuating abilities, depressed and unhappy, often experiences rapid emotional changes, and frequently experiences hallucinations.