bluuebunny/crossref_metadata_2025 huggingface dataset:
Clinical Study on the Effects of Different Positions on Supine Hypotensive Syndrome in Cesarean Section after Lumbar Anesthesia
Authors: Zhao Chunyan , Tang Yi , Chen Cibo , Xia Bingchun
Published: July 2021

Aim: To explore the effects of different positions on supine hypotensive syndrome in cesarean section after lumbar anesthesia. Methods: 600 full-term parturient were randomly divided into 4 groups. The patented positioning pads (patent number: ZL 2017 2 0618886.5) in our department was used in the left-leaning position. The parturient lied in a supine position for anesthesia in, and then the group of positioning pads was placed after turning into the lateral position. The parturient were divided into group A (supine position), group B (left-leaning to 10 °), group C (left-leaning to 20 °), and group D (30 °). Observation index: Main index: Comparison of maternal blood pressure changes and neonatal blood gas analysis in the supine position without using a position pad and with the use of patent positioning pads in different tilt angles (10°, 20°, 30°). Minor index: 1) the use and frequency of vasoactive drugs, whether a left-leaning operating bed or uterine displacement is required; 2) the consciousness of the parturient; 3) newborn’s Apgar scores of 1 minute, 5 minutes, and 10 minutes after birth; 4) whether the obstetrician can perform the operation smoothly in the corresponding left leaning position. Results: The blood pressure at the supine position after anesthesia, the beginning of surgery and the time when the newborn was delivered in group A and group B were significantly different from those in group C (P<0.05). There were significant differences at different timings in group A and group B, and the decline was more significant at the supine position after anesthesia, the beginning of surgery and the time when the newborn was delivered (P<0.05). The pH value of blood gas analysis of newborns in group A, group B and group C was between 7.25 and 7.37, and there was no significant difference between the three groups (P?0.05). Conclusion: The use of positioning pads can prevent the adverse effects of supine hypotensive syndrome on parturient and newborns to a certain extent.
The Effect of Minimally Invasive Spinal Trauma Surgery on Spinal Trauma
Authors: Peng Zhiyi
Published: July 2021

Objective: To study the effect of minimally invasive spinal trauma surgery on spinal trauma. Methods: After 60 patients with spinal trauma were selected, the patients in observation group was treated by minimally invasive spinal trauma surgery, while the patients in control group was given the routine treatment. Results: After treatment, the observation group improved significantly in operation related indexes, complication rate, pain degree, quality of life, JOA score and 0DI score(P<0.05). Conclusion: Minimally invasive spinal trauma surgery is effective in the treatment of spinal trauma.
Research Progress of Transurethral Prostatectomy for Benign Prostatic Hyperplasia with Bladder Stones
Authors: Shrestha Navin , Hu Huanchun , Zhou Le , Wang Bo
Published: July 2021

Benign prostatic hyperplasia, which can be abbreviated as prostatic hyperplasia, is a urinary system disease that has a high incidence in middle-aged and elderly male populations in China. The incidence of benign prostatic hyperplasia is increasing year by year. Patients with benign prostatic hyperplasia are prone to have bladder outlet obstruction, which in turn leads to an increase in residual urine volume in the bladder and impurities in the urine, such as upper urinary calculi that enter the bladder, urine crystals, various exfoliated cells, etc. If these substances stay in the bladder for a long time, stones in the bladder will be generated. Benign prostatic hyperplasia with bladder stones can severely obstruct the urinary tract, causing clinical symptoms such as urinary tract infections, urinary urgency, frequent urination, and dysuria. These symptoms seriously affects the physical and mental health of patients, leading to low levels of normal work and quality of life. With the development of medical technology, surgical treatment is commonly used in clinical practice. Among them, transurethral prostatectomy is widely used in clinical treatment, and has achieved good results.
A Comparative Study on the Efficacy between Minimally Invasive Caries Removal Technique involving Carisolv and Traditional Mechanical Caries Removal in Treating Dental Caries in Children
Authors: Song Jiaying
Published: July 2021

Objective: To explore the curative effect of Carisolv, a minimally invasive caries removal technique and traditional mechanical caries removal treatment on children's dental caries. Methods: A total of 97 children with dental caries who were treated in the Department of Stomatology in Affiliated Hospital of Chifeng University, Chifeng from September 2017 to May 2019 were selected and recruited as the research subjects. They were divided into two groups by random number table method. Forty-nine individuals were assigned in the control group while the remaining 48 individuals in the observation group. The control group was treated with traditional mechanical caries removal method, and the observation group was treated with minimally invasive caries removal technique, i.e. Carisolv. Both groups were followed up for six months. The degree of pain, recovery time of dental function and complications after six months of treatment were observed in the two groups of children. Results: During the treatment, compared with the control group, the children in the observation group experienced lower degree of pain and had shorter recovery time of dental function. After six months of treatment, the incidence of complications in the observation group was lower than that in the control group. The difference was statistically significant (P<0.05). Conclusion: Compared with traditional mechanical caries removal method, Carisolv, a minimally invasive caries removal technique could reduce the pain of children during the treatment process, shorten the time to restore dental function, reduce the occurrence of complications, and had a better therapeutic effect in treating children’s dental caries.
A Stusy of TMS For Extinction about Early Traumatic Memory Description
Authors: Xu Zhenzhen
Published: July 2021

Individuals will experience strong traumatic memories after traumatic events such as earthquakes, car accidents, or loss of loved ones, the most common of which is fear memory. In this experiment, a multi-sensory compound stimulation model (electric stimulation + picture) was used as the conditional stimulus, and the skin electrical response was used as the index of fear response. The effect of retrieval-extinction paradigm on the conditional fear extinction was tested. In addition, high-frequency rTMS was introduced as a treatment.To explore the therapeutic effect of TMS on conditional fear, with the aim of providing new measures for the treatment of PTSD.
Aesthetic Care in Cognitive-Behavioral Therapy for AN in China
Authors: Yang Ailin
Published: July 2021

Anorexia nervosa (AN) is a mental disorder, affecting mainly females in society. Understanding partially the factor of the disorder, researchers also designed several therapies to alleviate AN. Cognitive-behavioral therapy (CBT), which focuses on changing thought patterns of patients, and addressing inappropriate behaviors, is one of the beneficial therapies. In China, females whose disorder are caused by environmental factors are highly recommended to have CBT. To successfully realize the use of CBT to AN, we have to understand the strategy and treatment.
Research on the Effects of the Extract of Polygala fallax Hemsl on Sex Hormones and ?-EP in Perimenopausal Rat Models
Authors: Yang Siyuan , Cao Zhiyong , Chen Jiabao , Fang Gang
Published: July 2021

Objective: To study the effects of the ethnic medicine Polygala fallax Hemsl with Guangxi characteristics on the sex hormones and ?-EP in research objective perimenopausal rat models. Methods: 40 female SPF rats were randomly divided into 4 groups, including the normal, model, high-dose and low-dose groups. Rats of three groups except for the normal one were treated with perimenopausal modelling through the method of subcutaneous injection of compound 4-VCD for 15 consecutive days. Rats of the normal and model group were normally fed without any treatment. Rats of the high-dose and low-dose groups were administered by high- and low-dose intragastric administration of the extract of Polygala fallax Hemsl. According to the menstrual cycle of the vaginal smear of the rat, each menstrual cycle is a course of treatment and 6 consecutive courses of treatment would be given. The indexes of serum sex hormones (E2, FSH, LH) and ?-EP of rats in each group were observed after treatment. Results: After the treatment of 6 cycles, for the levels of ?-EP and E2, the model group was lowest (P<0.05), the normal group was highest (P<0.05); and the high-dose group was higher than the low-dose group; For the levels of FSH and LH, the normal group was lowest (P<0.05), the model group was highest (P<0.05), and the high-dose group was lower than the low-dose group. Conclusion: Guangxi characteristic national medicine Polygala fallax Hemsl can effectively improve the levels of serum sex hormones and ?-EP in perimenopausal rat models and relieve the related symptoms with a certain dose-effect relationship.
Evaluation of Early Acute Cerebral Infarction with Transcranial Doppler
Authors: Du Lilan , Cai Zhiyou
Published: July 2021

Objective: For patients with early acute cerebral infarction (ACI), transcranial Doppler ultrasound was used in the clinical examination, and its application effect was observed and analyzed. Methods: This study was carried out between October 2018 and October 2019. 50 patients with ACI included as the research object was evaluated by transcranial Doppler and CT examination, and the application of the two examination methods was compared. Results: The results of transcranial Doppler examination showed that the abnormal rate of blood flow velocity and the ratio of both sides (VACA) in patients with early ACI was higher than that of CT examination. Conclusion: With the impact on the location and area of vascular occlusion in patients, VACA can effectively reflect the status and effectiveness of the collateral circulation function of the patient’s pia vessels during cerebral infarction.
Study on the Clinical Effect of Dezocine and Remifentanil Combined with Propofol in Anesthesia for Painless Abortion
Authors: Wang Xin
Published: July 2021

Objective: To investigate the anesthetic effect of dezocine and remifentanil combined with propofol in painless artificial abortion. Methods: 90 cases in total of painless induced abortion in our hospital from May 2017 to May 2020 were retrospectively analyzed, 29 cases of propofol anesthesia (group A), 29 cases of dezocine combined with propofol anesthesia (group B), and 32 cases of remifentanil combined with propofol anesthesia (group C) were compared the anesthesia situation.  Results: Compared with the cases in group A, the incidence of pain, body movement and SPO2<90% at the injection site were lower in group B and group C, the use of propofol was reduced, and the VAS scores were lower when the patients begin to awake, and the efficiency was higher than that in group A(P<0.05); there was no statistic difference in the changes of SBP, DBP and HR index data in the operation time, postoperative awake time, and preoperative, intraoperative and postoperative time points of the three groups(P>0.05). Conclusion: Dezocine and remifentanil combined with propofol for painless artificial abortion anesthesia has more significant effect than propofol anesthesia alone, which can relieve patients' pain and reduce the chance of respiratory depression.
The Effect of Respiratory Rehabilitation Training on the Life Quality of Pneumoconiosis Patients
Authors: Chen Lijun , Xu Wang , Ma Xiaoyong , Yu Genggeng , Wang Jianfeng , Zhang Huifang
Published: July 2021

Objective: To explore the effect of respiratory rehabilitation training on the quality of life of pneumoconiosis patients. Methods: 76 pneumoconiosis patients who were treated in our hospital from April 2017 to December 2019 were selected as the research object, and randomly divided into 2 groups according to the order of admission by coin tossing, 38 cases in each group. The control group carried out health knowledge education on the basis of conventional treatment, and the observation group combined with respiratory rehabilitation training on the basis of the control group to compare the quality of life and lung function of the two groups of patients. Results: After 2 months of nursing care, scores of GQOLI-74 scale and pulmonary ventilation function indexes in the observation group were higher than those in the control group, with statistically significant differences (P<0.05). Conclusion: Respiratory rehabilitation training can improve pulmonary ventilation function of pneumoconiosis patients, improve the quality of life of patients, has good clinical application value.
Expression of SOX4 in Endometrial Cancer and its Relationship with Clinical-pathological Characteristics in Endometrial Cancer Patients
Authors: Liao Hongli , Lin Peng
Published: July 2021

Objective: Objective To investigate the expression of SOX4 in endometrial carcinoma tissues and its relationship with clinicopathological features. Methods: The clinical and pathological data of 51 patients with pathologically diagnosed endometrial carcinoma who underwent panhysterectomy in the Wenzhou Central Hospital from March 2017 to March 2019 were retrospectively analyzed. There were 22 cases of type I endometrial carcinoma and 29cases of type ? endometrial carcinoma. The immunohistochemical expression of SOX4 was detected, and its relationship with clinicopathological parameters was analyzed. Results: Compared with the control group, SOX4 in endometrial cancer group increased significantly (P<0.05); High SOX4 expression were closely related to differentiation, clinical stage and lymph node metastasis of endometrial cancer (P<0.05). Conclusion: SOX4 is related to the occurrence and development of EC. SOX4 may be a clinical evaluation index of EC and a reference index for clinical pathological diagnosis, it is helpful for clinicians to better analyze the high risk factors of EC patients and provide new ideas for early diagnosis, prognosis evaluation and targeted treatment of EC.
Effect of Zhuang Yi Liu Fang Teng Fang on the Expression of TNF-a and NF-kB in Chronic Pelvic Inflammatory Disease (CPID) Model Rats
Authors: Li Gang , Cao Zhiyong , Chen Jingqin , Chen Jingqin , Fang Gang
Published: July 2021

Objective: To investigate the expression of TNF-a and NF-kB in the uterus of chronic pelvic inflammatory disease (CPID) model rats. Methods: 40 female rats that adaptive fed for 5 days were randomly divided into normal group, model group, high dose group, medium dose group and low dose group. In addition to the normal group, the rats in each group were made chronic pelvic inflammatory model by mechanical injury combined with implantation of bacteria. The rats in each group were administrated by gavage for 20 days. After the last administration, the level of TNF-a and NF-kB in serum was measured by ELASA method. Results: (1) after the establishment of the model, the uterus of the chronic pelvic inflammatory model rats showed the pathological damage of chronic inflammation; the levels of TNF-a and NF-kB in serum were higher than those in the normal group, the difference was statistically significant (P<0.05). (2) After the drug intervention, the uterine tissue morphology of the rats in the Zhuang Yi Liu Fang Teng Fang Group was basically restored to normal, with only a small amount of inflammatory cell infiltration and other pathological changes; compared with the rats in the model group, the TNF-a in serum of the rats in each treatment group was lower, the difference was statistically significant (P<0.05). The expression of NF-kB in serum of each treatment group was lower than that of the model group (P<0.05). Conclusion: Zhuang Yi Liu Teng Fang can effectively improve the endometrial histomorphology of CPID model rats, and regulate the levels of TNF-a and NF-kB in the uterus of chronic pelvic inflammatory model rats.
Study on the Construction of Evaluation Index of Nursing Quality of Critically Ill Newborns
Authors: Yu Chunxia , Li Na
Published: July 2021

Objective: To achieve the effective construction of NICU nursing quality evaluation index and promote the necessary improvement of the success rate of treatment of critically ill newborns. Methods: The "structure-process-outcome" model was used to construct the necessary logical relationship for NICU nursing quality evaluation indicators. Then the NICU nursing quality evaluation indexes were initially established and defined accordingly. After that, the consultation scoring method was used to carry out the two rounds of questionnaire consultation, which was divided, deleted, and modified in the process. The second round of quality assessment indicators for critical neonatal care were used as research results. The establishment of the corresponding judgment matrix and the determination of the weighting relationship of each evaluation index were realized. Results: Forty-eight experts from 12 tertiary care children's hospitals in 9 provinces and cities in China participated in the questionnaire consultation. After the work, the resulting quality assessment indicators for critical neonatal care were agreed upon by all the experts. Sixty-seven quality indicators for critical neonatal care (18 process indicators) were evaluated based on the Structure-Process-Outcome (SPO) model. The necessary definitional work was achieved for the first round of questionnaire consultations (1 evaluation indicator, 19 structural indicators, 30 outcome indicators). In the first round of questionnaire consultations, eight evaluation indicators were deleted, one evaluation indicator was split, four evaluation indicators were added, and four indicators were added. Two evaluation indicators were combined. In the second round of questionnaire consultation, 5 evaluation indicators were removed, resulting in a more complete quality of care for critically ill newborns. Conclusion: Based on the "structure-process-outcome" model, the 58 indicators for evaluating the quality of tertiary NICU care were fully obtained. The unanimous approval of the consulting experts provides a solid foundation for the later stages of treatment of critically ill neonates.
Discussing Professor Zhang Xiaofeng's clinical experience in the diagnosis and treatment of menorrhagia by "Tongfa"
Authors: Li Zhe , Zhang Xiaofeng , Li Huan
Published: July 2021

Through the understanding, identification and treatment of menorrhagia, summarizing professor Zhang Xiaofeng's clinical experience in the treatment of menorrhagia, focusing on the identification of evidence, using "Tong" as the application, and treating in stages, he prepared Tongjing and Blood Regulating Soup and Tiaoping Tang as the basis for addition and subtraction, to harmonize the organs, qi and blood, Chong Ren and Uterus, in order to restore the balance of yin and yang and the function of Uterus in hiding and diarrhea.
Study on Effect of Laryngeal Mask Anesthesia and Endotracheal Intubation Anesthesia on Elderly Patients Undergoing Laparoscopic Gallbladder Surgery
Authors: Wang Xin
Published: July 2021

Objective: To analyze the effect of laryngeal mask anesthesia and endotracheal intubation anesthesia in elderly laparoscopic gallbladder surgery. Methods: 100 subjects of the experiment came from elderly patients with gallbladder stones admitted from September 2016 to September 2019 in our hospital. There were group A and group B of 50 cases each, and were used tube anesthesia and laryngeal mask anesthesia, then comparing the anesthesia effect. Results: Statistical significance(P<0.05): Air pressure and end-respiratory carbon dioxide partial pressure index changes when immediately after insertion, immediately after removal, 3 minutes after removal; heart rate, mean arterial pressure, airway pressure, and end-expiratory carbon dioxide index changes when 3 minutes after insertion and immediately before removal; blood glucose and cortisol changes when after insertion, immediately before removal and min after removal. No statistical significance(P>0.05): Changes in heart rate, mean arterial pressure, airway pressure, and end-expiratory carbon dioxide indexes before insertion; changes in blood glucose and cortisol indexes before insertion. Conclusion: It is more ideal for elderly patients with abdominal cavity and gallbladder surgery to have laryngeal mask anesthesia, which can effectively keep blood circulation stable and have promotion value.
Correlation Analysis of Intervertebral Disc Degeneration with HTRA1 and HAPLN1 Gene Polymorphisms
Authors: Guo Tuanmao , Xing Yanli , Chen Zhongning , Zhu Haiyun
Published: July 2021

The lumbar spine, an important part of the body's motor mechanism, is more susceptible to damage as it bears most of the body's load. Age can cause clinical manifestations such as neurological impairment, back and leg pain in the lumbar spine. External forces result in nucleus pulposus out, destruction of the intervertebral disc fibrous ring, and gradual aging and damage. Lumbar degenerative change is a common middle-aged and old-aged disease, and its clinical symptoms on the initial stage are not obvious, but it becomes more and more serious as they get older. Patients with severe lumbar degenerative changes will appear symptoms such as urinary and fecal incontinence, lower extremity numbness, back pain, and sexual dysfunction. The main reason for back pain and leg pain is the degenerative changes in the lumbar intervertebral discs, at the same time which also leads to patients' lumbar instability. This study focuses on the correlation analysis of intervertebral disc degeneration with HTRA1 and HAPLN1 gene polymorphisms.
Clinical Research Progress of Acupuncture and Massage Treatment in Pediatric Cerebral Palsy
Authors: Wang Lin , Luo Shijie
Published: July 2021

Pediatric cerebral palsy is a common refractory disease in pediatrics, which has not only a high disability rate, but also a significant impact on the growth and daily learning of children. At present, the clinical treatment of pediatric cerebral palsy is diversified, and the curative effect is different. Among the many therapies, acupuncture and massage have the characteristics of safety, economy, and efficiency, which has unique advantages in treating the disease. However, due to the irregularity of the acupoint selection experience and manipulation, the evaluation of clinical efficacy is different. Therefore, it is necessary to summarize, analyze and organize the clinical research of acupuncture and massage treatment of pediatric cerebral palsy, in order to provide guidance and reference for clinical and follow-up research. This paper sorts out the relevant literature, and reviews the treatment of pediatric cerebral palsy from the aspects of acupuncture and massage.
Multivariate Analysis of Femoral Adductor Muscle Contracture after Total Hip Arthroplasty in Patients with Avascular Necrosis of Femoral Head
Authors: Meng Lin , Zhang Dong , Wei Qing , Zhan Xinli , Cai Jinhong , Li Hongyu
Published: July 2021

Objective: This study is to investigate the risk factors of femoral head contracture after total hip arthroplasty (THA) in patients with avascular necrosis of femoral head. Methods: Retrospective analysis was performed in 361 cases of femoral head necrosis patients taking THA from September 2016 to December 2017. A total of 179 patients with no significant preoperative adductor muscle contraction were finally enrolled in this study. These 179 patients were further divided into two groups: contracture group (64 cases) and noncompaction group (115 cases). The chi-square test was used to compare the differences between the two groups. Risk factors were identified by logistic regression analysis. Results: Of the patients included, 64 patients (35.75%) developed into end adductor muscle contracture. There were significant differences in limb shortening, surgical history, whether traction, surgical approach, surgical methods, and functional training between the two groups (P<0.05). Logistic regression analysis showed that shortness of extremity, surgical approach, effective traction, surgical history, and etiology were the factors affecting femoral head contracture after THA in patients with avascular necrosis of femoral head. Conclusions: Preoperative traction therapy, surgical methods, and postoperative functional training are the factors that affect the adductor muscle contraction after THA.
Study on Endoscopic Treatment of Non-Varicose Upper Gastrointestinal Bleeding
Authors: Li Danyang , Hui Jianping
Published: July 2021

Upper gastrointestinal bleeding is a common clinical disease with a relatively high incidence rate, and it is also an acute bleeding disease with a greater impact. If not rescued in time, it will greatly threaten the patient's physical and mental health and may even be fatal, especially in cases of non-varicose upper hemorrhage, which is closely related to digestive ulcers. In most cases, related diseases are self-limiting. However, some of the cases are relatively urgent and require internal meridian treatment to promote coagulation and improve existing disease situation. For endoscopic treatment process, related treatment methods have certain specificities, and their characteristics need to be fully understood.
Effect of Osteoporotic Vertebral Compression Fracture on Adjacent Intervertebral Disc Degeneration
Authors: Guo Tuanmao , Xing Yanli , Chen Zhongning , Zhu Haiyun
Published: July 2021

Objective: The influence of vertebral compression fracture on the degeneration of adjacent disc was analyzed. Methods: 88 patients with osteoporotic vertebral compression fractures admitted to the orthopedic pain department from July 2014 to July 2019 were selected as the research objects. According to the previous MRI and the improved MRI results of admission, the patients were converted into old fractures after conservative treatment. They were followed up in 3, 6 and 12 months after discharge, and the VAS score at each time point (visual acuity score) was calculated We collected and analyzed the classification of intervertebral disc degeneration and MRI index. Results: The follow-up rate was 65.9% (58/88);There were 42 cases (72.4%) of degenerative disc adjacent to the diseased vertebra, and 16 cases (27.5%) of adjacent intervertebral disc did not degenerate; VAS scores were lower at 14 days, 3 months, 6 months and 12 months after admission; The number of grade 1 of disc degeneration was lower in 6 months and 12 months than that in admission (P<0.05), and the number of grade 2, 3 and 4 was significantly higher than that in the follow-up in December (P<0.05). The difference between 6 and 12 months was not statistically significant (P>0.05); MRI index at 6 and 12 months follow-up was lower than that at admission (P<0.05). Conclusion?Through the research and analysis, we found that osteoporotic vertebral compression fracture will have a corresponding impact on the adjacent intervertebral disc, which can make the adjacent intervertebral disc degenerate.
Zhang Hongxing’s Experience in Exogenous Cough Treatment
Authors: Zhou Renjie , Zhang Hongxing
Published: July 2021

Cough is a common clinical symptom, throughout history the medical experts have different discussions on the diagnosis and treatment of cough and put forward different theories on the treatment of cough. Chief physician Zhang Hongxing is a famous old doctor of traditional Chinese medicine in Dezhou city with rich experience in clinical practice and unique academic thoughts. In the treatment of exogenous cough, Director Zhang stressed that the differentiation of syndromes should be focused on ‘wind’ and pay attention to the role of liver ‘wind’ in cough. The prescription of medicines should emphasize on dispelling the ‘wind’ first, to dispel the external ‘wind’, but also to calm the internal ‘wind’, and making good use of Uncaria in medicine. Valuable experience for clinical diagnosis and treatment of exogenous cough was provided.
Clinical Study of Acupotomy Trinity Lysis on Cervical Spondylotic Myelopathy with Liver and Kidney Deficiency Syndrome
Authors: Gao Jianyong , Zhao Yi , Sun Tinglan , Liu Weike , Wang Zhenguo
Published: July 2021

Objective: To compare the therapeutic effects of acupotomy trinity lysis and traditional acupotomy on cervical spondylotic myelopathy. Methods: A total of 205 patients with cervical spondylotic myelopathy of liver and kidney deficiency syndrome were randomly divided into the experimental group (105 cases) and the control group (100 cases). The experimental group was relaxed with acupotomy in three positions: Heaven (tian), Human (ren) and Earth (di). Traditional acupotomy was used to relax Ashi acupoints of the affected vertebra in the control group. One treatment was conducted in one week, and the duration of one course of treatment was three weeks. The VAS, JOA score and NDI index were observed after treatment.  Results: Before and after treatment, the total treatment efficiency of the treatment group was 95.23%, and that of the control group was 80.00%, there was significant difference between the two groups, P<0.05; Before operation, there was no significant difference in JOA score, NDI index score, and VAS score between the treatment group and the control group (P>0.05); there was no significant difference after 1 week (P>0.05), but there were significant differences between the two groups 2 weeks and 3 weeks after operation (P<0.05). Conclusion: Acupotomy trinity lysis is a safe, effective and economical treatment for cervical spondylotic myelopathy.
Observations on the Preventive Effects of Anti-infective Treatment on Wound Infection in Emergency Surgery
Authors: Zhao Zhiyong
Published: July 2021

Objective: To explore the preventive effects of anti-infective treatment on wound infection in emergency surgical trauma. Methods: 180 patients in our hospital from 2019 to June to May 2020 were selected as subjects. The 180 patients were randomly divided into two groups. The control group had 90 cases and adopted the conventional treatment method, and the experimental group received anti-infective treatment. The wound healing, infection status, and patient satisfaction of the two groups of patients were analyzed. Results: The wound healing, infection status, and patient satisfaction of the experimental group were better than those of the control group. Conclusion: The application of anti-infective treatment to the prevention of wound infection in emergency surgical trauma can reduce the infection rate of the patients' incision and promote the recovery of patients. It is suitable for clinical applications.
Unique Traditional Chinese Medicine Therapy for Painful Diabetic Peripheral Neuropathy
Authors: Chai Jinjin , Wang Defen
Published: July 2021

Painful diabetic peripheral neuropathy is one of the common chronic complications of diabetes. "Pain" is the most typical symptom in patients, which seriously affects their quality of life. Traditional Chinese medicine (TCM) treatment of the disease includes oral administration of Chinese medicine, TCM fumigation and acupuncture, etc., which can significantly reduce the pain of patients and reduce the frequency of disease. Chinese decoctions regulate the imbalance of yin and yang in the human body through syndrome differentiation, so as to achieve the balance of yin and yang, which will then eliminate the disease. Chinese medicine fumigation make the medicine seep into the body from the skin to exert the medical effects, and nourish and dredge the meridians. There is no pain if the meridians are smooth flowing, there will be pain if the meridians are blocked, fumigation can be used alone or assisted by other treatment methods to enhance the efficacy. The characteristics of acupuncture are rapid pain-relief, economic and convenient, and can quickly relieve pain for patients with low tolerance.
Research Progress of TCM Treatment of Uterine Fibroids
Authors: Lu Xiaoyu , Hu Xinjie , Chen Mei
Published: July 2021

Uterine fibroids are the most common benign tumors in gynecology. Traditional Chinese medicine treats uterine fibroids according to syndrome differentiation and treatment. The treatment of uterine fibroids has the characteristics of definitive curative effects and minor side-effects, but there are also many shortcomings, which require more in-depth research and exploration.
Investigation of Cognition Status of Menopausal Hormone Therapy in Medical Institutions Staff
Authors: Xu Guanying , Geng Xinran , Wang Yaqiong , Yang Guixia
Published: July 2021

Objective: To investigate the cognition, application and commendation of menopausal hormone therapy (MHT) among medical institution staff with different professional background. Methods: Female staff aged 40-60 years in 4 tertiary hospitals were randomly selected. The participants’ characteristics and the information of cognition, application and recommendation of MHT were collected by questionnaire. Results: A total of 341 people participated in this study, the cognition rate of MHT was 37% and the recommendation rate was 44%. For people with indications of MHT, the utilization rate is 15%, and 84.6% of them have used MHT for less than 3 years. 84.6% of those who did not use MHT considered menopause is not a disease and there was no need to use medication. Compared with nurses, doctors know more about MHT (P<0.01), and MHT recommendation rate of doctors was higher than that of nurses(P<0.01). The cognition of MHT were analyzed in menopause group, irregular menstruation group and regular menstruation group, there was no difference was found among these three groups (P>0.05). Conclusion: Strengthening the training of MHT related knowledge in medical institutions, will be helpful to improve the cognition and utilization rate of medical institutions and promote the whole society to study and use MHT.
Therapies of SARS-CoV-2
Authors: Wang Tianqi
Published: July 2021

The Coronavirus disease 2019 (COVID-19) pandemic caused by SARS-CoV-2 has resulted in a severe global health crisis. There are no current specialized therapies available to the virus. However, several possible treatments show some effectiveness on treating the virus, such as medication, convalescent plasma therapy, and vaccine. This paper will discuss and evaluate the effectiveness of these treatments on SARS-CoV-2.
Research on Government Emergency Management Strategy Based on Public Health Incidents
Authors: Yang Wenjuan
Published: July 2021

It is the government's basic responsibility to ensure public health safety. However, due to the influence of the environment and human beings, some public health incidents are still inevitable, endangering public health and undermining social stability. However, any public health incident is traceable, and there will be a process from latent period to outbreak. Therefore, the government needs to grasp the key points of health incidents, strengthen emergency management, and ensure social stability and public safety.
Analysis of the Effect of Infection Control in Hospital Operation Room
Authors: Li Junling , Lv Honglei
Published: July 2021

Objective: To explore the implementation effect of nursing management in operating room for hospital infection control. Methods: 100 cases of patients who received surgical treatment in our hospital from 2019 to 2020 were selected and divided into observation group and control group according to different nursing management methods in operating room. Patients in the control group received routine nursing management services, while patients in the observation group received systematic and high-quality comprehensive management services based on routine nursing management services. Results: The air colony count and hand colony count of the observation group were significantly better than those of the control group. At the same time, the incidence probability of infection in the observation group was also significantly lower than that of the control group, with significant difference between the groups, with statistical value (P < 0.05). Conclusions: In view of the occurrence of nosocomial infection, the implementation of high-quality operating room nursing service can effectively control it, reduce the probability of occurrence, and ensure the safety of patient treatment, which is worthy of clinical application.
Effect of Continuous Nursing on Quality of Life of Patients with Diabetes Mellitus
Authors: Lv Honglei , Li Junling
Published: July 2021

Objective: To analyze the effect of continuous nursing on the quality of life of patients with diabetes. Methods: From August 2019 to August 2020, 76 patients with diabetes were selected and randomly divided into group A and group B. group a received continuous nursing and group B received routine nursing. Results: The compliance of health education in group A was better than that in group B (P < 0.05);The score of quality of life in group A was better than that in group B (P < 0.05);The scores of anxiety and depression in group A were better than those in group B (P < 0.05);The nursing satisfaction of group A was 97.37%, which was better than that of group B 76.32%, P < 0.05.Conclusions: Continuous nursing for patients with diabetes can improve the quality of life, relieve anxiety, depression and other negative emotions, and improve nursing satisfaction.
Application of Cluster Intervention Strategy in Patients with Stroke Associated Pneumonia
Authors: Jia Hongfang , Hao Jing
Published: July 2021

Objective: To study and analyze the clinical effect of cluster intervention strategy in patients with stroke associated pneumonia. Methods: The time span of the study was from April 2018 to March 2019. 70 stroke patients were selected and divided into the study group and the control group according to the random number table model. The control group was treated with routine nursing, and the study group was treated with cluster intervention. The indicators of the two groups were compared and analyzed. Results: Compared with the incidence of aspiration and stroke associated pneumonia, the study group had more advantages (P< 0.05). Conclusion: Cluster intervention can significantly reduce the incidence of associated pneumonia in stroke patients, which is worthy of comprehensive promotion.
Renal Tubular Dysgenesis Associated with Compound Heterozygous ACE Mutations
Authors: Liu Yiran , Wang Xueyan
Published: July 2021

Inherited renal tubular dysgenesis(RTD), a rare, autosomal recessive disorder is caused by mutations in the genes encoding components of the renin-angiotensin pathway: angiotensinogen(AGT), renin (REN), angiotensin-converting enzyme(ACE), and angiotensin ?? receptor type 1(AGTR1). It characterized by the absence or poor development of renal tubules, and associated with oligohydramnios, Potter sequence and neonatal death due to renal or respiratory failure. We report a family with two mutations in the coding region of the ACE gene: a nonsense mutation in exon4 (c.538C>T) and a frameshift deletion at nucleotide 3073 and nucleotide 3074 in exon20(c.3073_3074delTC). The mutations were in the compound heterozygous state causing disease, because each parent had their own  mutation.
Effects of Denervation on the Mid-term Results of Knee Joint Functions after Non-resurfaced Total Knee Arthroplasty
Authors: Liu Ningning , Su Huanhuan , Wang Yuanhe , Zhang Yu , Yu Hongjian
Published: July 2021

Objective: Total knee arthroplasty (TKA) has become an effective treatment modality for end-stage osteoarthritis and rheumatoid arthritis. Postoperative problems such as anterior knee pain affect postoperative patient satisfaction. Patellar denervation has been proposed as a technique to relieve pain, but its efficacy remains controversial. This study evaluated the mid- and long-term effects of patellar denervation on postoperative knee joint functions, hoping to provide better guidance for clinical practice. Methods: This study is a prospective randomized controlled double-blind study. 58 patients undergoing bilateral non-resurfaced total knee arthroplasty were included and randomized into two groups. Both groups underwent total knee arthroplasty while patellar denervation was performed only on the experimental group. Information regarding whether if patellar denervation was performed were withheld from all patients and outcome assessors. All surgeries were performed by the same high-level professional physician, and the post-stable knee prosthesis system (PS Scorpio NRG PS, Stryker) was used during the surgeries. The knee joint functions were evaluated by professional assessors before and after surgery. The evaluation indicators mainly include KSS scoring, Western Ontario and McMaster Universities (WOMAC) scoring and Visual Analogue Scale (VAS), FJS scoring, etc. The follow-up period was 3 years and 5 years after surgery. Results: The experimental group had better KSS and FJS scores than the control group, the difference was statistically significant. There was no significant inter-group difference in WOMAC and VAS scores. Conclusion: The patellar denervation in TKA patients has positive effects on the mid- and long-term recovery of knee joint functions, and the postoperative satisfaction is better.
Perioperative Nursing Observation of Plasma Radiofrequency Ablation for Treatment of Lumbar Intervertebral Disc Herniation
Authors: Sun Hui , Tang Guo , Li Dan , Wang Lei
Published: July 2021

Objective: To observe and analyze the perioperative nursing effect of plasma radiofrequency ablation for treatment of lumbar disc herniation. Methods: A total of 100 patients with lumbar intervertebral disc herniation received from October 2017 to October 2020 were selected and randomly divided into two groups with 50 cases in each group. The control group received the conventional nursing model and the experimental group received the comprehensive nursing model. The two groups of nursing care were compared on satisfaction, SDS and SAS scores before and after treatment, VAS score and JOA score before and after treatment, and treatment effect. Results: The nursing satisfaction of the experimental group, SDS and SAS scores before and after treatment, VAS score and JOA score before and after treatment, and the treatment effect were better than those of the control group. The difference was statistically significant (P<0.05). Conclusion: The comprehensive nursing model has a significant effect on the perioperative nursing of the treatment of lumbar intervertebral disc herniation by plasma radiofrequency ablation. More popularization and application will help improve the treatment effect.
Role of Fine Management in Maintenance of Deep Venous Indwelling Catheter in Hemodialysis Patients
Authors: Teng Fei
Published: July 2021

Objective: This paper mainly explores the effect of fine management application in maintenance of deep venous indwelling catheter in hemodialysis patients. Methods: 150 hemodialysis patients with deep venous catheter indwelling in our hospital from December 2019 to September 2020 were divided into routine group and study group. The routine group was given routine nursing, and the study group was given fine management nursing. The nursing effect of the two groups was analyzed. Results: After nursing intervention, the incidence of complications in the study group was 14.66%, which was lower than that in the conventional group (53.33%), and the nursing compliance in the study group (98.66%) was higher than that in the conventional group (89.33%), all P < 0.05. Conclusion: Fine management plays a significant role in the maintenance of deep venous indwelling catheter in hemodialysis patients, which can reduce the occurrence of complications.
Discussion on the Mechanism of Action of High-frequency Drugs for Treating Heart Failure Based on Network Pharmacology
Authors: Lei Feifei , Zhao Mingjun , Wang Haifang , Pan Chao , Shi Xiaoya
Published: July 2021

Objective: To explore the target and mechanism of Astragalus membranaceus, poria, salvia miltiorrhiza and semen leiocarpa in the treatment of heart failure by network pharmacology. Methods: The active components of traditional Chinese medicine and the target of heart failure were screened by multi-platform, and the standard gene was transformed by Uniprot. CytoCasp 3.6.1 was used to draw the network diagram of traditional Chinese medicine - component - target. Go and KEGG analysis were performed by Metascape. Results: A total of 36 predictive target sites of Radix Astragalus, Fuling poria, Salvia miltiorrhiza and Draba nemorosa were screened for treatment of heart failure, mainly involving nerve and factor pathways: ADRB2, ADRA1B and AChE. Cancer pathway: TP53, TNF; Pathways of inflammation: IL1B, PTSG2, PTSG1; Sex hormone pathway: ESR1, AR, PGR; Others: SCN5A, HIF1A, etc. The results of GO and KEGG enrichment suggested that the treatment of heart failure with the top four drugs involved cancer pathway, calcium signaling pathway, HIF-1 signaling pathway, and involved in blood circulation, cell proliferation and other processes. Conclusion: This study combines the pharmacological studies of Chinese medicine and western medicine to reveal the mechanism of multi-target and multi-channel regulation of body balance in Chinese medicine treatment.
Sharing of Psychological Nursing Experience of Patients with COVID-19
Authors: Cheng Juan , Zhang Xiaoyan
Published: July 2021

The author nursed suspected and confirmed cases of COVID-19 imported from abroad in a mobile hospital. During the front-line work in the fight against the epidemic in 2020, emergency response measures and corresponding clinical nursing experience have been accumulated for public health emergencies. This article summarized and shared the psychological nursing of patients with COVID-19 during the work of the author.
Effect of Cinepazide Maleate Combined with Promethazine Hydrochloride in the Treatment of Emergency Vertigo
Authors: Yi Jun , Zhou Yincai , Cheng Xinghao
Published: July 2021

Objective: To explore the effect of cinepazide maleate combined with promethazine hydrochloride in the treatment of emergency vertigo. Methods: 48 cases of emergency vertigo patients in our hospital from November 2017 to November 2019 were divided into experimental group (24 cases, treated with cinepazide maleate combined with promethazine hydrochloride) and control group (24 cases, treated with cinepazide maleate). The clinical efficacy, symptom relief time, adverse reactions and quality of life were compared. Results: The total effective rate of the experimental group (95.83%, 23 / 24) was higher than that of the control group (75.00%), The remission time of nausea and vomiting (1.75 ± 0.22) d, vertigo (3.54 ± 0.63) d, deafness and tinnitus (3.47 ± 0.58) d, night sweats (3.05 ± 0.33) d in the experimental group were shorter than those in the control group, P < 0.05; the incidence of adverse reactions in the experimental group (8.33%, 2 / 24) was lower than that in the control group (33.33%, The scores of social function, material life attitude, physical health and psychological function in the experimental group were 59.14 ± 7.23, 54.05 ± 8.04, 53.58 ± 8.86 and 60.11 ± 8.44 respectively, P < 0.05. Conclusion: In the process of clinical treatment of emergency vertigo patients, the combined application of cinepazide maleate and promethazine hydrochloride has definite curative effect, can relieve clinical symptoms in a short time, has less adverse reactions, and improves the quality of life of patients to a certain extent, which is worthy of promotion.