bluuebunny/crossref_metadata_2025 huggingface dataset:
Face morphology of brazilian and peruvian populations: analysis of proportion and linear measurement indexes
Authors: Dos Santos Elaine Cristina Sousa , Pimentel Diego Jesus Bradariz , De Matos Laís Lopes Machado , Magri Laís Valencise , Da Silva Ana Maria Bettoni Rodrigues , Da Silva Marco Antônio Moreira Rodrigues
Published: September 2017

Objective: To compare the proportion and linear measurement indexes between Brazilian and Peruvian population through 3D stereophotogrammetry and to stablish the face profile of these two Latin American populations. Material and Methods: 40 volunteers (Brazilian n=21– 10 males and 11 females; Peruvian n=19 – 8 males and 11 females) aged between 18 and 40 years (mean of 28.7±9.1) had landmarks marked on the face. Then, 3D images were obtained (VECTRA M3) and the indexes of proportion and linear measurement (face, nose, and lips) were calculated. The data were statistically analyzed by One-Way ANOVA (p<0.05). Results: The proportion indexes did not reveal marked differences either between the studied populations or genders (p>0.05). The following linear measurements showed intergroup statistically significant differences: face width and height, nose width and height, upper facial height, mouth width, protrusion of the nose tip (p<0.05). The Brazilian females showed the smallest significant differences. Conclusions: Despite the different ethnic compositions, the Brazilian and Peruvian populations did not differ regarding the proportions of the face, nose, and lips. The differences observed in Brazilian females may be related to gender and/or to the Caucasian heritage of the Brazilian sample.KeywordsPhotogrammetry; Face; Tridimensional Image.
Soziales Engagement in der Flüchtlingshilfe
Authors: Beckmann Fabian , Hoose Fabian , Schönauer Anna-Lena
Published: September 2017

Wurde das Engagement für Geflüchtete in Deutschland im Sommer 2015 zunächst als positives Beispiel einer neuentdeckten ‚Willkommenskultur‘ gewertet, hat sich das gesellschaftliche Klima seitdem zusehends polarisiert. Der vorliegende Beitrag untersucht die Einstellungen zum Engagement für Geflüchtete in der Bevölkerung. Die Befunde zeigen, dass das Flüchtlingsengagement schichtübergreifend deutlich negativer beurteilt wird als Engagement im Allgemeinen. Negative Einstellungsmuster werden dabei insbesondere durch wahrgenommene gesellschaftliche Gerechtigkeitsdefizite begünstigt.
Adaptation of Chain Event Graphs for use with Case-Control Studies in Epidemiology
Authors: Keeble Claire , Thwaites Peter Adam , Barber Stuart , Law Graham Richard , Baxter Paul David
Published: September 2017

Case-control studies are used in epidemiology to try to uncover the causes of diseases, but are a retrospective study design known to suffer from non-participation and recall bias, which may explain their decreased popularity in recent years. Traditional analyses report usually only the odds ratio for given exposures and the binary disease status. Chain event graphs are a graphical representation of a statistical model derived from event trees which have been developed in artificial intelligence and statistics, and only recently introduced to the epidemiology literature. They are a modern Bayesian technique which enable prior knowledge to be incorporated into the data analysis using the agglomerative hierarchical clustering algorithm, used to form a suitable chain event graph. Additionally, they can account for missing data and be used to explore missingness mechanisms. Here we adapt the chain event graph framework to suit scenarios often encountered in case-control studies, to strengthen this study design which is time and financially efficient. We demonstrate eight adaptations to the graphs, which consist of two suitable for full case-control study analysis, four which can be used in interim analyses to explore biases, and two which aim to improve the ease and accuracy of analyses. The adaptations are illustrated with complete, reproducible, fully-interpreted examples, including the event tree and chain event graph. Chain event graphs are used here for the first time to summarise non-participation, data collection techniques, data reliability, and disease severity in case-control studies. We demonstrate how these features of a case-control study can be incorporated into the analysis to provide further insight, which can help to identify potential biases and lead to more accurate study results.
In defence of the case study methodology for research into strategy practice
Authors: Hughes Jeff , McDonagh Joe
Published: September 2017

This paper aims to illustrate how the case study methodology may be used in novel and productive ways for research into strategy practice. Instigated by the quest for a research design that could target the ‘practice’ of strategic information systems planning (SISP), a review of the strategy-as-practice (SAP) literature uncovered parallels with the SISP domain from a methodological standpoint. A SAP perspective was employed in conjunction with the case study methodology to investigate SISP (the strategy practice) on the part of senior managers (the practitioners) at the meso level (the level of praxis). Ultimately, this approach was found to offer original insights and uncover valuable new directions for future academic enquiry.
Synthesis of unexpected novel bis-coumarin derivatives
via
three component reactions of 4-hydroxycoumarin, aldehydes and cyclic secondary amines. Conformation in the solid state and pharmacological evaluation
Authors: El-Samahy Fatma A. , El Salam Hayam A. Abd , El-Sayed Naglaa F. , Shalaby Elsayed M. , Dondeti Mahmoud F.
Published: September 2017

A series of unexpected bis-coumarins have been synthesized by multicomponent reactions of 4-hydroxycoumarin, aldehydes, and cyclic secondary amines in ethanol at room temperature. The chemical structures of new compounds were identified by 1H, 13C NMR, and mass spectrometry. Furthermore, the molecular structure of the solid-state adduct of 3,3′-[(4-methoxyphenyl)-methylene]bis(4-hydroxy-2H-chromen-2-one) with morpholine (1:1) has been confirmed by single-crystal X-ray diffraction. The cytotoxicity of the new coumarin derivatives against MCF7 breast cancer cells was evaluated. A docking study of the new products was carried out to assess the molecular affinity between the tested compound and Topoisomerase IIa.
PERBANDINGAN JUMLAH TIKUS YANG TERTANGKAP ANTARA PERANGKAP DENGAN UMPAN KELAPA BAKAR, IKAN TERI DENGAN PERANGKAP TANPA UMPAN (STUDI KASUS DI WILAYAH KERJA PUSKESMAS PANDANARAN) TAHUN 2015
Authors: Junianto Sadita Dwi , Siwiendrayanti Arum
Published: September 2017

Puskesmas Pandanaran merupakan Puskesmas dengan jumlah kejadian leptospirosis di Kecamatan Semarang Selatan paling tinggi dengan jumlah pada tahun 2014 sebanyak 10 kasus. Tujuan penelitian ini adalah untuk mengetahui perbandingan jumlah tikus yang tertangkap antara perangkap dengan menggunakan umpan kelapa bakar, ikan teri dan perangkap tanpa menggunakan umpan dilihat dari jumlah tikus yang tertangkap.Jenis penelitian ini adalah Jenis penelitian yang digunakan adalah penelitian eksperimen semu (eksperimen kuasi). Teknik pengambilan sumber informasi yang digunakan adalah teknik purposive sampling, dengan jumlah sampel 50 rumah.Hasil penelitian ini didapatkan data tikus yang tertangkap dengan kelapa bakar adalah 42 ekor, dengan ikan teri adalah 32 ekor dan perangkap tanpa umpan adalah 1 ekor dengan angka trap succes kelapa bakar 12%, ikan teri 9,14% dan perangkap tanpa umpan 0,29%. Berdasarkan uji Man Whitney menunjukan ada perbedaan keberhasilan penangkapan tikus antara kelapa bakar dengan perangkap tanpa umpan (p=0,001 < α=0,005), ikan teri dengan perangkap tanpa umpan (p=0,001 < α=0,005) dan tidak terdapat perbedaanpenangkapan tikus antara kelapa bakar dengan ikan teri (p=1,000  < α=0,005).Saran yang dapat diberikan yaitu: Melakukan pengendalian tikus di rumah masing-masing, menggunakan umpan yang menarik bagi tikus, Menjaga sanitasi lingkungan dan menerapkan perilaku hidup bersih dan sehat agar terhindar dari risiko penularan leptospirosis yang dibawa oleh tikus.

Pandanaran Health Center has the highest number of leptospirosis in South Semarang District with 10 cases in 2014. The purpose of this study was to determine the comparison of the number of rats caught betwen the trap with the use of roasted coconut, anchovy bait and traps without the use of bait as seen from the number of rats being caught. The type of research used in this study was quasi experimental research. The sampling technique used in this study was the purposive sampling technique, with a total sample of 50 houses. The results of this study showed that the number of rats caught with roasted coconut was 42 rats, with anchovy was 32 rats and trap without bait was 1 rats, the trap success number of roasted coconut was 12%, anchovy was 9.14% and without bait was 0.29 %. Man Whitney test showed that there was a difference between the success of catching rats with roasted coconut bait and traps without bait (p = 0.001 <α = 0.005), anchovy bait and traps without bait (p = 0.001 <α = 0.005) and there was no difference between roasted coconut bait and anchovy bait (p = 1.000 <α = 0.005). Advice can be given as follows: to conduct rats control in the neighborhood, to use a tempting bait for rats, to maintain sanitation and apply a clean and healthy lifestyle in order to avoid the risk of leptospirosis infection carried by rats.
UJI DAYA BUNUH GRANUL EKSTRAK LIMBAH TEMBAKAU (NICOTIANAE TABACUM L ) TERHADAP LARVA AEDES AEGYPTI
Authors: Khalalia Rizki
Published: September 2017

Pengendalian penyakit DBD bergantung pada pengendalian larva Aedes aegypti. Penggunaan insektisida nabati perlu dikembangkan untuk mengurangi dampak negatif insektisida kimia. Limbah tembakau merupakan tanaman yang mengandung zat alkaloid, saponin dan flavonoid yang berfungsi sebagai insektisida. Penelitian ini dilakukan untuk mengetahui efektivitas pemberian ekstrak limbah tembakau (Nicotiana tabacum L.) dalam bentuk granul untuk membunuh larva Aedes aegypti.  Jenis penelitian ini adalah eksperimen murni, dengan rancangan post test only with control group design dengan lima variasi konsentrasi ekstrak sebesar 10%, 15%, dan 20%, dengan empat kali pengulangan. Hasil uji menunjukkan terdapat hubungan antara ekstrak limbah tembakau dalam bentuk granul dengan kematian larva (p=0,001).  Analisis probit didapatkan LC50 granul ekstrak  limbah tembakau adalah 59,506% dan LC90 adalah 1.163,619%. LT50 pada konsentrasi 20% adalah 790,787 menit, sedangkan LT90 adalah 2.820.000 menit. Saran peneliti adalah perlu dilakukan penelitian lebih lanjut mengenai cara menghilangkan warna pada air yang diberi ekstrak limbah tembakau dalam bentuk granul.

The efforted to control dengue fever depended on control of the Aedes aegypti larvae. The used of natural insecticides should be developed as easily biodegradable in nature. Tobacco waste in Indonesia is very abundant amount of 55776.24 tonnes per year. Tobacco waste contains alkaloid, essential oil, nicotine and flavonoid which its function as insecticides. This research was conducted to know the effectiveness granule extract tobacco waste (Nicotiana tabacum L.) to kill Aedes aegypti larvae. This research was true experimental research, with the design of post test only with control group with three variations of the extract concentration 10%, 15%, dan 20% with four times repetitions.This research was conducted in 2016. The result showed that there was corelation between Nicotiana tabacum L.extract in granul with larvae mortality (p=0.001). From probit analysis test, LC50 was found in 23,965% and LC90 in 4 0,957%. LT50 of 20% was 362.625 hours, while LT90 was 544.488 hours. The conclusion of this study is granule extracts of tobacco waste has larvicidal effect on Aedes aegypti larvae.
ID: 1040 Anticancer effects of natural products from animal and plant origin
Authors: Gajshi Goran , Madunić Josip , Madunić Ivana Vrhovac , Čimbora-Zovko Tamara , Rak Sanjica , Breljak Davorka , Osmak Maja , Garaj-Vrhovac Vera
Published: September 2017

For last couple of decades, natural products have served us well in combating different types of cancer. The main sources of these useful compounds are from both animal and plant origin. Here we will present anticancer ability of bee venom (BV) and apigenin (API) towards different types of cancer cells in vitro. BV from honey bees is a complex mixture of a variety of different active peptides while API is a natural flavonoid found in several dietary plant foods. Anticancer effect of whole BV was tested in human cervical carcinoma HeLa cells and their drug-resistant HeLa CK subline while anticancer effect of API was tested in human breast cancer MCF-7 and MDA MB-231 cells. Cytotoxicity of both compounds towards cancer cells was evaluated by MTT assay whereas type of cell death was analysed by differential staining using acridine orange/ethidium bromide and was further verified by Western blot analysis. BV displayed dose-dependent cytotoxicity against both cell lines tested with drug-resistant HeLa CK cells being more sensitive to BV than their parental cell lines. Similarly, API inhibited the growth of both cell lines in a dose-dependent manner with MCF-7 cells being more sensitive. Treatment with BV induced a necrotic type of cell death, as shown by characteristic morphological features, fast staining with ethidium bromide and a lack of cleavage of apoptotic marker poly (ADP-ribose) polymerase (PARP) on Western blot. On the contrary, cell treated with API showed apoptosis as a dominant type of cell death in both cell lines which was further verified by Western blot analysis detecting cleaved PARP. In view of accumulating evidence on anti-proliferative and pro-cell death activity, both tested compounds could be used in the development of future anticancer drugs. Undoubtedly, therapeutic applications of BV and API are promising, however further in vitro and in vivo studies are warranted to resolve precise mechanisms responsible for their anticancer properties
Anthropology with algorithms?
Authors: Krieg Lisa Jenny , Berning Moritz , Hardon Anita
Published: September 2017

Based on a study of more than twenty thousand reports on drug experiences from the online drug education portal Erowid, this article argues that the integration of ethnographic methods with computational methods and digital data analysis, including so-called big data, is not only possible but highly rewarding. The analysis of ‘natively’ digital data from sites like Facebook, message boards, and web archives can offer glimpses into worlds of practice and meaning, introduce anthropologists to user-based semantics, provide greater context, help to re-evaluate hypotheses, facilitate access to difficult fields, and point to new research questions. This case study generated important insights into the social and political entanglements of drug consumption, drug phenomenology, and harm reduction. We argue here that deep ethnographic knowledge, what we term ‘field groundedness’, is indispensable for thoroughly making sense of the resulting visualizations, and we advocate for seeing ethnography and digital data analysis in a symbiotic relationship.
No country for young girls?
Authors: Sams Kelley , Kaba Arnaud
Published: September 2017

n/a
Developing an integrated model for quelling illegal mining in South Africa
Authors: Mkhize Mbekezeli Comfort
Published: September 2017

Despite being recognised as a significant contributor in the South African economy, the mining industry is riddled with illegal mining activities. Though it remains difficult to precisely measure the extent of the activities in financial terms, it is estimated that more than R72 Billion have been lost. Lack of research on illegal mining partly compounds the problem. In view of this knowledge-gap, this article argues that whilst there is a multiplicity of stakeholders who deal directly with unlawful activities, poor integration of capacities at different levels remain discernible. The article assesses available literature and employs two theoretical perspectives as lenses through which to view the underlying reasons and the measures that can be put in place to quell illegal mining. The article concludes that an integrated model needs to be put in place in order to quell illegal mining in South Africa. The article recommends that the resources need to be pulled together and collaborative efforts need to be enhanced at all levels.
Human Rhinovirus Association with Influenza-Like Illness and Symptomatic Treatment for Acute Respiratory Infection in a Brazilian Southern City
Authors: Morais Fernando Seiji , Bonilha Caio S. , Carraro Emerson
Published: September 2017

Acute respiratory infections (ARI) are the world’s leading cause of morbidity and mortality. ARI impairs children’s education and have a huge impact on the economy. Human rhinovirus (HRV) is the most prevalent agent of ARI. In this study, a clinical and epidemiological surveillance in outpatients was carried to investiga-te the involvement of HRV in ARI cases in the city of Guarapuava, a Brazilian southern city. Attention was also given to the most common medications used for treating ARI symptoms. Samples from 135 patients were col-lected from Apr to Dec from 2014, HRV was identified in nearly 20% of samples, with symptoms ranging from common cold to Influenza-like Illness (ILI) and was more frequent in individuals with 10 or less years-old. Ne-arly two thirds of patients reported use of at least one class of drug during the ARI episodes, such as analgesi-cs, cough and cold preparations, and NSAIDs. In some cases and with no justifiable reason, patients also repor-ted the use of antibiotics, possibly contributing to the development of bacterial resistance. These results show a significant detection rate of HRV in ARI cases, and highlight the impact of this virus in the local population.
Russia’s Narratives of Global Order: Great Power Legacies in a Polycentric World
Authors: Miskimmon Alister , O'Loughlin Ben
Published: September 2017

This article takes a strategic narrative approach to explaining the current and likely future contestation between Russia and the West. We argue that Russia projects a strategic narrative that seeks to reinforce Russia’s global prestige and authority, whilst promoting multilateral legal and institutional constraints on the other more powerful actors, as a means to ensure Russia stays among the top ranking great powers. To illustrate this we analyze Russia’s identity narratives, international system narratives and issue narratives present in policy documents and speeches by key players since 2000. This enables the identification of remarkably consistency in Russia’s narratives and potential points of convergence with Western powers around commitment to international law and systemic shifts to an increasingly multipolar order. However, we explain why the different meanings attributed to these phenomena generate contestation rather than alignment about past, present and future global power relations. We argue that Russia’s historical-facing narratives and weakened material circumstances have the potential to hamper its adaptation to rapid systemic change, and to make attempts to forge closer cooperation with third parties challenging.
Entrevista com Claudia Beltrão da Rosa: apontamentos sobre a pesquisa em História Antiga no Brasil
Authors: Rosa Claudia Beltrão da
Published: September 2017

Entrevista com Claudia Beltrão da Rosa: apontamentos sobre a pesquisa em História Antiga no Brasil.
Entre o cultural e o político: as 'Epistulae Heroidum', de Ovídio, à luz dos estudos de gênero (I a.C.-I d.C.)
Authors: Medeiros Mariana Carrijo
Published: September 2017

O que hoje compreendemos como naturalização e construções culturais, sociais, políticas e históricas dos sexos feminino e masculino também foram praticadas, incessantemente, na Antiguidade Clássica. Levando-se em consideração que os estudos de gênero, em sintonia com a História Cultural e Política, nos possibilita historicizar tais relações e investigar as formas como cada sociedade as construíram, propomo-nos, no presente artigo, a realizar considerações acerca dos modelos ideais de cidadão e de matrona romana (re)construídos ao longo do Principado de Augusto e a forma como estes modelos estão presentes em Epistulae Heroidum, do poeta latino Ovídio (I a.C./ I d.C.). Optamos por realizar nossas considerações a partir dos tópoi recorrentes nesta obra, por acreditarmos que eles auxiliaram na naturalização, nas tentativas de homogeneização e na atribuição do que é ser homem e do que é ser mulher nesta sociedade.
Book Reviews
Authors: Stadlober Ernst , Friedl Herwig , Wagner Helga , Konecny Franz , Grossmann Wilfried , Leopold Ulrike , Böhm Bernhard , Katzenbeisser Walter , Schachermayer Walter , Viertl Reinhard
Published: September 2017

Die Industriestatistik Europas im Umbruch. (M. Müller)Statistik. DerWeg zur Datenanalyse. (L. Fahrmeir, R. Künstler, I. Pigeot, G. Tutz)Einführung in die Stochastik. (R.K.W. Viertl)Probability Theory III. (Y.V. Prokhorov, A.N. Shiryaev)Functional Data Analysis. (J.O. Ramsay, B.W. Silverman)Business Analysis Using Regression. (D.P. Foster, R.A. Stine, R.P. Waterman)Applied Regression Analysis. A Research Tool. (J.O Rawlings , S.G. Pantula, D.A.Dickey )Econometric Analysis of Count Data. (R. Winkelmann)MartingaleMethodes in FinancialModelling. Theory and Applications. (M.Musiela,M. Rutkowski)Conference on Statistical Science Honouring the Bicentennial of Stefano Franscini’sBirth. (C.A.G. Malaguerra, St. Morgenthaler, E.M.D. Ronchetti)
Das Bundesstatistikgesetz 2000 aus der Sicht des universitären Statistikers
Authors: Bauer Peter , Hackl Peter
Published: September 2017

Der universitäre Statistiker hat naturgemäß besonderes Interesse an methodischen Fragen, die allerdings für die Sicherung der Qualität der Ergebnisse von statistischen Analysen ganz allgemein von großer Relevanz sind. In diesem Sinn wurde bereits im Herbst 1997 aus Anlaß einer Podiumsdiskussion argumentiert und entsprechende Wünsche an ein künftiges Bundesstatistikgesetz geäußert (siehe den Beitrag eines der Autorenin ”Wünsche an ein Österreichisches Bundesstatistik-Gesetz“, ÖsterreichischeZeitschrift für Statistik, 26 (1997), 71–84). Ein zweites Thema, das für die Arbeit universitärer Statistiker von Wichtigkeit ist, betrifft die Möglichkeit des Zugriffs auf Daten und statistische Ergebnisse aus dem Bereich der Amtlichen Statistik. Im vorliegenden Beitrag soll dargelegt werden, inwieweit das Bundesstatistikgesetz 2000 (im Folgenden mit BSG 2000 abgekürzt) den Vorstellungen des universit¨aren Statistikers entspricht und welche Wünsche es offen läßt.
Coherent Risk Measures and Convex Combinations of the Conditional Value at Risk (C V@R)
Authors: Pflug Georg Ch.
Published: September 2017

The conditional-value-at-risk (C V@R) has been widely used as a risk measure. It is well known, that C V@R is coherent in the sense of Artzner, Delbaen, Eber, Heath (1999). The class of coherent risk measures is convex. It was conjectured, that all coherent risk measures can be represented as convex combinations of C V@R’s. In this note we show that this conjecture is wrong.
Nonparametric Rank Tests for Independence in Opinion Surveys
Authors: Yu Philip L.H. , Lam K.F. , Alvo Mayer
Published: September 2017

Nonparametric rank tests for independence between two characteristics are commonly used in many social opinion surveys. When both characteristics are ordinal in nature, tests based on rank correlations such as those due to Spearman and Kendall are often used. The case where some ties exist has already been considered whereas Alvo and Cabilio (1995) have studied the case when there are missing values but no ties in the record. However, it frequently happens that the survey data may contain simultaneouslymany tied observations and/or many missing values. A naive approach is to simply discard the missing observations and then to make use of the rank correlations adjusted for ties. This approach would be less powerful as it does not fully utilize the information associated with the incomplete data set. In this article, we generalize Alvo and Cabilio’s notion of distance between two rankings to incorporate tied and missing observations, and define new test statistics based on the Spearman and Kendall rank correlation coefficients.We determine the asymptotic distribution of the Spearman test statistic and compare its efficiency with the corresponding statistic based on the naive approach. The proposed test is then applied to a real data set collected from an opinion survey conducted in Hong Kong.
«Человек войны» Иван Бородатов в историческом контексте войны и мира
Authors: Жукова Ольга Германовна
Published: September 2017

Рецензия на издание: Бородатов И. Я. Жить прекрасно (Страницы жизни простого советского человека). — М. : ЗАО «Издательство ИКАР», 2016. — 207 с.
Simbiogenetics of microbe-plant interactions
Authors: Tikhonovich Igor A , Provorov Nikolay A
Published: September 2017

We present the concept of symbiogenetics defined as a branch of general genetics which investigates the Super-Organism Genetic Systems (SOGS) formed due to functional integration of partners' genes during symbiotic interactions. The minimal hereditary unit within SOGS involves no less than a pair of genes that belong to different partners and interact according to the models of complementation or epistasis. Using the examples of plant-microbe interactions we demonstrate that the integrity of SOGS is maintained due to tight signal interactions between partners and is manifested as formation of common biochemical pathways and as development of special symbiotic structures. Using the models of nodule development we demonstrate that the origin of SOGS involves recruiting of genes, which performed diverse functions in free-living organisms, into the symbiotic regulatory networks. The progressive evolution of nodule structures in different dicot lineages was based on the parallel recruiting of genes from the ancestral gene pool into symbiotic regulatory networks. The majority of mutualistic and antagonistic plant-microbe symbioscs represent the components of an evolutionary continuum that originated early in land plants and underwent intensive transformations due to high plasticity of SOGS based on inter- and intra-gene recombination.
Interplay of Darwinian and frequency-dependent selection in the host-associated microbial population
Authors: Vorobyov Nikolay I , Provorov Nikolay A
Published: September 2017

The method for mathematical simulation is suggested to analyze the balanced polymorphism in rhizobia population generated due to the interplay of Darwinian and frequency-dependent selection. Analysis of the model suggested that this polymorphism is determined not only by the selection pressures but also by the capacities of ecological niches occupied by bacteria in the «plant-soil» system. The model may be used for analyzing the selective processes in various symbiotic systems and for predicting the consequences of releasing of genetically modified plant symbionts into environment.
Association of promoter region polymorhism of the tnfб gene with the development of atopic bronchial asthma
Authors: Ostankova Julia V , Ivashchenko Tatyana E , Zhelenina Ludmila A , Baranov Vladislav S
Published: September 2017

Atopic bronchial asthma (ABA) is a complex genetic disease characterized by increased airway responsiveness to a variety of stimuli, reversible airway obstruction, and airway inflammation. The genetic polymorphisms -238 A/G and -308 A/G of the TNFA gene were studied by PCR-RFLP analysis in the group of asthmatic patients with age of manifestation before 18 years (83) and the population group (117). According to obtained data the frequency of -238A allele of the TNFA gene was significantly lower in the group of patients with ABA (1,2%) as compared to the population group (5,6%). The analysis of distribution of the G -308A polymorphism of the TNFA gene revealed significant increase of the frequency of -308A allele in the patients with ABA (9,0%) as compared to the population (4,0%). According to odds ratio the careers of -308A allele of the TNFA gene have 2-fold increased risk of the development of ABA (OR = 2,48; CI: 1,06-5,82). The frequency of -308A allele of the TNFA gene in the group of patients was significantly higher in women (14,8 %) as compared to men (2,6 %, p = 0,0064, df = 1). After comparing the distribution of genotypes of -238 and -308 polymorphisms of the TNFA gene together significant difference between patients with ABA and population was observed. Combined genotype -238A/G + -308G/G of the TNFA gene associated with the lowest level of gene expression resulted in considerable decrease of ABA risk (OR = 0,097). Different hypotheses of the role of polymorphic variants of the TNFA gene in pathogenesis of ABA were discussed.
Diversity of nocardio- and coryneform bacteria in soil adjacent to pig farm treatment installation
Authors: Shibaeva Maria E , Kvitko Konstantin V , Andronov Evgeniy E , Arkhipchenko Irina A
Published: September 2017

Effect of excessive active sludge on soil microbial communities has been studied at «Vostochny» pig farm treatment installation in the Leningrad oblast. Comparative evaluation of genetic and physiological diversity of nocardio - and coryneform bacteria in soil adjacent to the reservoir for active sludge waste accumulation has been carried out.
Genotoxicity of the pestiside in Ames test and the possibility to formate the complexeses with DNA
Authors: Saratovskikh Elena A , Glazer Vadim M , Kostromina Natalya Yu , Kotelevtsev Sergey V
Published: September 2017

The Ames test (strains Salmonella typhimurium тА98 and тА100) was used to study mutagen activity of seven pesticides: six herbicides (roundup, zenkor basagran, kusagar, lontrel, setoxidim), and fungicide tachigaren, also as herbicide complexes lontrel with eight metals (Cu, Co, Zn, Ni, Fe, Мп, Mo, Mg). It is positioned, that mutagen indexes of the investigated pesticides correlate with the value constant of formation the complexes these substances with DNA. Complexes lontrel (MLsub2/sub) with all metals have displayed mutagen activity. Genotoxicity NiLsub2/sub, FeLsub2/sub, ZnLsub2/sub it is close to genotoxicity initial lontrel, at complexes with other metals have genotoxicity in 1,5-2 times lower.
Loss of allelic diversity in species of hybrid origin
Authors: Grebelnyi Sergey D
Published: September 2017

Species of hybrid origin support their population as a rule by cloning. Switching over of any bisexual organism to propagation by means of parthenogenesis, gynogenesis, androgenesis (or other kind of apomictic reproduction without regular recombination, which usually accompanies change of generations in bisexual species) leads to rapid decrease of genetic polymorphism. Long-term cloning transforms the polymorphic population or entire species into a mixture of only a few clones, composed of genetically identical individuals. owing to selection in favour of heterozygotes or due to hybrid origin, natural clonal populations commonly are of high heterozygosity. Selection, genotypic uniformity and high heterozygosity often give to clonal race or species selective advantages, but at the same time they inevitably result in loss of most of alleles. Inasmuch as new forms, reproductively isolated from parental species, are products of hybridization of only a small number of individuals, which succeed in overcome the interspecies barrier, the hybridization itself also plays role of a very narrow bottle neck. The well established opinion that recombination and allelic diversity are necessary conditions for successful evolution on the basis of gene frequency changes, comes now into contradiction with the available data concerning the polyploid and, probably, hybrid origin of many groups of flowering plants and vertebrate animals.
Cytogenetic response of seed progeny of scots pine to combined anthropogenic pollution in the area of Novolipetsk metallurgical combine
Authors: Mashkina Elena V , Kalaev Vladislav N , Muraya Lidia S , Lelikova Ekaterina S
Published: September 2017

The comparative estimation of variability cytogenetic parameters at seed progeny of pine ordinary from ecologically favorable and from industrial (Novolipetsk metallurgical combine - «NLMK») regions is carried out. It is established, that in progeny of pine trees growing in territory of «NLMK» there is an essential change of cytogenetic parameters in comparison with the control. It has been revealed that among seed progeny there are «mutable» and «low-mutable» forms. Questions of adaptation of seed progeny of pine ordinary trees to stressful factors at cellular and sub cellular levels are discussed.
Multi-component symbiosis of Legumes with beneficial soil microbes: genetic and evolutionary basis of application in sustainable crop production
Authors: Shtark Oksana Y , Borisov Aleksey U , Zhukov Vladimir A , Nemankin Timofey A , Tikhonovich Igor A
Published: September 2017

Leguminous plants have a genetic system that provides interaction with different beneficial soil microorganisms (BSM). The system has been formed on the basis of the genetic mechanisms that had arisen during the co-evolution of plants with arbuscular-mycorrhizal (AM) fungi and appeared to provide pre-adaptations for further evolution of interaction with various BSM. A concept of the use of BSM in sustainable agriculture is proposed, which postulates an establishment of the multi-component beneficial plant-microbe communities based on varieties of legumes with high potential for interaction with the BSM.
Effect of LIM kin ase 1 is oform ratio on Drosophil a mel anogaster courtship behavior: a complex approach
Authors: Kaminskaya Alena N , Nikitina Ekaterina A , Payalina Tatyana L , Molotkov Dmitry A , Zakharov Gennady A , Popov Andrey V , Savvateeva-Popova Elena V
Published: September 2017

LIMK1 - is the key enzyme of actin remodeling which controls dendritic spine morphology necessary for synaptic plasticity during learning and memory formation. Conditioned courtship suppression paradigm and a set-up for communicative sound production during courtship were used to asses learning acquisition and memory formation in four Drosophila strains polymorphic for the limk1 gene harbored by the agnostic locus: the wild type strains Canton-S, Berlin, Oregon-R and the mutant аgnts3. Behavioral performances were compared to the brain content and ratio of two LIMK1 isoforms in these Drosophila strains.
Babies and Art Museums: welcoming discoveries
Authors: Carvalho Cristina , Santos Maria Emília Tagliari
Published: September 2017

The offer of educational actions focused on babies in museums causes the need for studies that seek to understand such actions, contributing to the constitution of significant practices. From these activities the article presents a reflection on the relationship between art and early childhood. The text was guided by theorists who value the cultural aspect in children's development, especially by Rinaldi and Vecchi. Institutional documents were used, such as photographic records and articles, as well as observations of some activities. It sought to identify ways that can stimulate the extension of the reception to the public from zero to three years in cultural institutions.

Bebês e Museus de Arte: acolhendo descobertas

A oferta de ações educativas em museus voltadas para bebês provoca a necessidade de estudos que busquem compreender tais ações, contribuindo para a constituição de práticas significativas. A partir dessas atividades, o artigo apresenta uma reflexão sobre a relação entre arte e primeira infância. O texto foi orientado por teóricos que valorizam o aspecto cultural no desenvolvimento infantil, em especial por Rinaldi e Vecchi. Foram utilizados documentos das instituições, como registros fotográficos e artigos, além de observações de algumas atividades. Buscou-se identificar caminhos que podem estimular a extensão do acolhimento ao público de zero a três anos nas instituições culturais.
Significance of Brand name in Brand Loyalty-An Empirical Study in Automobile Sector
Authors: Malhan Shivani , Tandon Manvinder
Published: September 2017

This paper attempts to examine whether the consumer is brand conscious and he thinks that the brand name is important for him or not. According to the pilot study and interview method applied in this paper, the most important attributes considered by the customers while repurchasing the car are Price, Comfort and safety, Brand name and Customer Service. The study is based on primary data, collected from Jalandhar city of Punjab. Conjoint analysis is employed to determine which combinations of a limited number of attributes are most influential for the respondents while taking a decision in purchase of passenger car. In conjoint analysis, we use full profile approach in which profiles are reduced using orthogonal array approach. The empirical findings reiterate that consumers in this region experience that the most important attribute in Brand Loyalty is comfort and safety. This is because customers think that the features like front passenger airbags, advanced braking systems and air conditioning are very essential in the today are set up. The second important determinant of Brand Loyalty is price which may be accounted to affordability of the customer. The customers have also given relevance to customer service because the process of building the relationship with customer starts with the purchase of car but it keeps on evolving after the sale. The least importance is given to the attribute - brand name as per the empirical findings of the study.
Emotional Intelligence and Work Engagement as Mediators of Big Five Personality and Knowledge Sharing
Authors: Ansari Amirul Hasan , Talan Amogh
Published: September 2017

The purpose of this paper is to examine the interrelationships among various interpersonal psychological factors to explain their effect on knowledge sharing behaviors at workplace. A sample of 450 employees was drawn from knowledge based industries. To tap the information regarding performance on knowledge sharing, Big Five personality, Emotional intelligence and work engagement, Knowledge Sharing Behavior (KSB) scale by Yi (2009)56, Big Five personality traits scale by Gosling et. al. (2003)21, Workgroup Emotional Intelligence Profile (WEIP-S) by Jordan & Lawrence (2009)26 and Utrecht Work Engagement Scale by Schaufeli et. al. (2003)46 have been used. Partial Least Square technique of Structural Equation Modeling was applied using SmartPLS 2.0.M3 to understand the proposed relationships. Findings show the prominence of conscientiousness among Big Five personality traits to explain knowledge sharing behaviors at workplace (Total Effect of conscientiousness on knowledge sharing being 0.5246 significant at p<0.01). Emotional intelligence proves to be the most important mediator of the relationship between Big Five traits, except agreeableness, and knowledge sharing. Even though work engagement is found to be a significant predictor of knowledge sharing (Total Effect of work engagement on knowledge sharing being 0.1698, significant at p<0.01), its role as a mediator is minor. Although the paper has certain limitations, nevertheless, this is the first study to consider the relationship between personality, emotional intelligence, work engagement and knowledge sharing in a single study and making us understand the interacting and mediating role of emotional intelligence and work engagement to explain knowledge sharing.
Open Edition
Authors: Board Editorial
Published: September 2017

Open Edition is run by the Centre for open electronic publishing (Cleo – UMS 3287), a unit that brings together the Centre National de la Recherche Scientifique (CNRS), the universite d’Aix-Marseille, the Ecole des Hautes Etudes en Sciences Sociales (EHESS) and the Universite d’Avignon et des Pays de Vaucluse.
3 International Conference on Engineering Confluence (Eqinox 2017)
Authors: Board Editorial
Published: September 2017

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Мониторинг реализации стандарта развития конкуренции в Свердловской области
Authors: Коковихин Александр Юрьевич , Огородникова Екатерина Сергеевна Екатерина Сергеевна , Плахин Андрей Евгеньевич
Published: September 2017

В статье представлены результаты исследования уровня удовлетворенности потребителей и представителей организаций малого и среднего бизнеса конкурентной средой на рынках Свердловской области.
Цель исследования, ставшего основой настоящей статьи определение подходов к реализации мониторинга мероприятий Стандарта развития конкуренции в субъектах Российской Федерации.
Комплексные подходы к осуществлению мониторинга представлены в исследованиях, проведенных в 2015-2017 гг на территории Свердловской области: «Исследование комплексной оценки состояния инвестиционного климата в муниципальных образованиях, состояния инвестиционного климата в муниципальных образованиях, расположенных на территории Свердловской области» (государственный контракт № 0162200032215000009-0657446-01) и «Мониторинг наличия (отсутствия) административных барьеров и оценки состояния конкурентной среды субъектами предпринимательской деятельности и мониторинг удовлетворенности потребителей качеством товаров, работ и услуг на товарных рынках Свердловской области и состоянием ценовой конкуренции на территории Свердловской области» (государственный контракт № 04-2017-14).
Данные об удовлетворенности конкурентной средой потребителей и представителей организаций в 2016 году получены в ходе опроса более 1000 респондентов в 72 городских округах и муниципальных районах Свердловской области. Данные об объективных результатов государственной и муниципальной политики получены из размещенных в 2016 году докладов Глав муниципальных образований Свердловской области о достигнутых значениях показателей для оценки эффективности деятельности органов местного самоуправления.
Результаты исследования позволяют разработать ряд рекомендаций по улучшению институциональной среды деятельности субъектов МСП. Разработанные предложения рекомендуются к использованию органами государственной власти и местного самоуправления при разработке политики повышения удовлетворенности конкурентной средой потребителями и представителями организаций.
Politik Hukum Perundang-Undangan Pasar Modal Syariah di Indonesia
Authors: Adirianto Adirianto
Published: September 2017

This article aims to describe how the policy formation of Islamic Capital Market Law in Indonesia. This article is based on research using the normative approach to law (statute approach) and the conceptual approach (conceptual approach). The results of the discussion of this article shows that the formation of Law No. 8 of 1995 on Capital Market from the approach used in the Draft Law on Capital Market is divided into two, namely the Institutional Approach and Approach Activities. From that approach then can the problem to design the Law on Capital Market that have been showcased in the Problem Inventory List (DIM) to conduct further discussion process in the Establishment Act Concerning the Capital Market. Other factors are reflected in very strong sociological aspects of coverage that would pihakpihak governed by this Law which covers all players in the capital market, which is any party that has an interest in the activity modal an outlets and public companies.
Artikel ini bertujuan mendeskripsikan bagaimana kebijakan pembentukan Undang-undang Pasar Modal Syariah di Indonesia. Artikel ini berdasarkan penelitian normatif dengan menggunakan pendekatan perundang-undangan (statute approach) dan pendekatan konseptual (conceptual approach). Hasil pembahasan artikel ini menunjukkan bahwa terbentuknya Undang-Undang No. 8 Tahun 1995 tentang Pasar Modal dari pendekatan yang digunakan dalam Rancangan Undang-undang tentang Pasar Modal dibagi dua, yaitu Pendekatan Kelembagaan dan Pendekatan Aktivitas. Dari pendekatan itu maka di dapat masalah untuk merancang Undang-Undang tentang Pasar Modal yang sudah di tuangkan dalam Daftar Inventarisasi Masalah (DIM) untuk melakukan Proses Pembahasan selanjutnya dalam Pembentukan Undang-Undang Tentang Pasar Modal. Faktor lainnya secara aspek sosiologisnya tercermin sangat kuat dari cakupan pihakpihak yang kelak diatur oleh Undang-Undang ini yang mencakup seluruh pelaku Pasar Modal, yaitu setiap pihak yang mempunyai kepentingan dengan aktivitas kepasar modalan dan perusahaan publik.
El debate constitucional de 1931 en España sobre la libertad de conciencia: una discusión de las relaciones entre Iglesia y Estado = The 1931 Spanish constitutional debate on freedom of conscience: a discussion about the relations between Church and State
Authors: Bellido Francisco J.
Published: September 2017

Resumen: Este estudio analiza el debate parlamentario de 1931 en España, en el marco del debate sobre la nueva Constitución, en torno a la libertad de conciencia a través de las relaciones entre Iglesia y Estado que los distintos partidos políticos perfilan. Defiende que el debate sobre la libertad de conciencia es, sobre todo, un debate sobre el papel de estas dos instituciones en el nuevo orden constituyente. En la primera parte de este trabajo se recogen las intervenciones parlamentarias que configuran el debate constitucional sobre la libertad de conciencia durante septiembre de 1931. Junto a ellas se exponen algunos de los factores políticos que ayudan a entender el contexto del debate constitucional en esas fechas. En la segunda parte se introducen precisiones sobre el vocabulario político de los constituyentes, enfatizando la necesidad de prestar atención al uso de conceptos políticos comunes: secularización, autonomía, libertad y Estado. En la tercera parte se examinan, al hilo de las intervenciones parlamentarias del debate constitucional a lo largo de octubre de 1931, los argumentos aducidos por los diputados de las distintas formaciones y se recapitulan las razones que sostienen la hipótesis de trabajo.Palabras clave: Debate constitucional español de 1931, Constitución española de 1931, libertad de conciencia, Iglesia y Estado en España, vocabulario político de la Segunda República.Abstract: This study examines the Spanish parliamentary debate of 1931, in the framework of the debate on the new Constitution, about freedom of conscience through the relations between Church and State outlined by the different political parties. It defends that the debate on freedom of conscience deals mainly with the role of both institutions in the new constituent order. The first part of this article shows parliamentary sessions on freedom of conscience that took place in September 1931. In the second part some clarifications regarding the political vocabulary used by the constituents are introduced. It pays attention to the use of common political: secularisation, autonomy, liberty and State. In the third part the arguments held by the representative during October 1931 are examined. Finally, it summarises the arguments supporting the article’s hypothesis.Keywords: Spanish constitutional debate of 1931, Spanish Constitution of 1931, freedom of conscience, church and state in Spain, political vocabulary of the Spanish Second Republic.
Desarrollo (evolución internacional) = Development (international evolution)
Authors: Resina de la Fuente Jorge
Published: September 2017

Resumen: Este artículo analiza la construcción histórica y legal del concepto de desarrollo en el ámbito internacional, desde su institucionalización a mediados del siglo XX hasta la aprobación en 2015 de la Agenda 2030 de Desarrollo Sostenible por parte de las Naciones Unidas. Para ello, se plantea un estudio sobre cómo evoluciona el término a través de un recorrido por los distintos contextos en los que aparece y los debates que se generan en torno a cuestiones como crecimiento, sustentabilidad o capacidades humanas.Palabras clave: Desarrollo, Sostenibilidad, Desarrollo Humano, Cooperación Internacional, Agenda 2030.Abstract: This article analyzes the historical and legal construction of the concept of development in the international arena, since its institutionalization in the middle of the twentieth century to the adoption of the 2030 Agenda for Sustainable Development by the United Nations in 2015. To do this, we study how the term evolves through the different contexts in which it appears, and what debates are generated, with issues such as growth, sustainability or human capabilities.Keywords: Development, Sustainability, Human Development, International Cooperation, 2030 Agenda.