bluuebunny/crossref_metadata_2025 huggingface dataset:
Análise da Autorregulação Formativa Territorial no Espírito Santo na percepção de médicos e gestores
Authors: Cunha Clarice Sampaio , Cardoso Andréa Lanzillotti , Rendeiro Marcia Maria Pereira
Published: November 2024

Resumo A Autorregulação Formativa Territorial foi implantada em todos os municípios do Espírito Santo em 2020 e consiste em um modelo de atenção que pretende reorganizar os processos de trabalho desde a atenção primária até o nível hospitalar. Este manuscrito teve por objetivo analisar a satisfação de médicos e gestores em saúde quanto à realização dessa autorregulação na região de saúde sul do estado. Trata-se de um estudo descritivo, documental, com abordagem qualitativa. O público pesquisado reuniu médicos cardiologistas e psiquiatras, médicos de atenção primária, gestores de Atenção Primária à Saúde e o gestor de um núcleo regional de especialidade. Os resultados demonstraram que os entrevistados perceberam que a Autorregulação Formativa Territorial contribui para a aproximação da Atenção Primária à Saúde com a atenção especializada, porém ainda não há redução do tempo e filas de espera para as especialidades analisadas. Conclui-se que esse modelo pode representar uma oportunidade de contribuição para a prestação de serviços de saúde por meio da possibilidade de melhora no acesso, na eficiência e na qualidade do cuidado, além de reduzir os custos operacionais.
Monitoramento e avaliação para o controle social do Sistema Único de Saúde: reflexões sobre o agir formativo
Authors: Leandro Bianca Borges da Silva , Martins Fernanda do Nascimento , Kabad Juliana Fernandes , Lopes Reinaldo de Araujo Dantas , Marques Larissa Pruner , Cruz Marly Marques da
Published: November 2024

Resumo O contexto do Sistema Único de Saúde é atravessado por diversas iniciativas formadoras direcionadas aos profissionais de saúde, aos gestores e à sociedade civil organizada, dentre as quais destacam-se os processos relacionados à temática do monitoramento e avaliação em saúde. Contudo, pouco se observam iniciativas nessa área voltadas para o controle social do referido sistema. O objetivo deste artigo é analisar a trajetória formativa e pedagógica do curso de formação em monitoramento e avaliação para o controle social no Sistema Único de Saúde, de modo a delinear reflexões e apontamentos pertinentes a processos formativos destinados a pessoas conselheiras e apoiadoras técnicas atuantes nos espaços de participação social em saúde. Trata-se de um artigo com orientação informativa, referenciada, dialogada e crítica, subdividido em três seções. Na primeira, recupera-se o referencial teórico a respeito da relevância de processos formativos na área de monitoramento e avaliação em saúde; na segunda, apresentam-se as bases pedagógicas e metodológicas do curso; na terceira, são sistematizados desafios e potencialidades da vivência do processo formativo dialogados à luz da literatura técnico-científica da área.
Decoding Consumer Sentiments: Advanced NLP Techniques for Analyzing Smartphone Reviews
Authors: Jabeen Shaista
Published: November 2024

ABSTRACT Objectives: this study aims to bridge the gap in effectively analyzing online consumer feedback on smartphones, which is often voluminous and linguistically complex. The ultimate goal is to provide smartphone manufacturers with actionable insights to refine product features and marketing strategies. We propose a dual-model framework using bidirectional encoder representations from transformers (BERT) and sentence transformers for sentiment analysis and topic modeling, respectively. This approach is intended to enhance the accuracy and depth of consumer sentiment analysis. Method: sentiment analysis and topic modeling are applied to a large dataset of smartphone reviews sourced from Kaggle and Amazon. The BERT model is used to understand the context and sentiment of words, while sentence transformers generate embeddings for clustering reviews into thematic topics. Results: our analysis revealed strong positive sentiments regarding smartphone performance and user experience, while also identifying concerns about camera and battery life. However, while the model effectively captures positive feedback, it may struggle with negative feedback and especially neutral sentiments, due to the dataset’s bias toward positive reviews. Conclusions: the application of BERT and sentence transformers provides a significant technological advancement in the field of text analysis by enhancing the granularity of sentiment detection and offering a robust framework for interpreting complex data sets. This contributes to both theoretical knowledge and practical applications in digital consumer analytics.
The Impact of IT-Business Strategic Alignment on The Transformation and Operations of Pre-Digital Businesses
Authors: Mendes-da-Silva Francisco Massaro , Albertin Alberto Luiz
Published: November 2024

ABSTRACT Objective: this study aims to answer the following research question: How does IT-business strategic alignment (ITBSA) influence the sustaining or transformation of a pre-digital business? This objective was defined due to the critical importance of this topic for executives responsible for keeping such businesses adaptive and competitive in the face of the digital era’s opportunities and threats. Theoretical approach: the theoretical background of this article is formed by pre-digital and digital business models, IT-business strategic alignment, focusing on IT-enabled business support, IT-enabled business transformation, digital optimization, and digital transformation. Method: following the development of a research model and propositions, a case study was conducted using semi-structured interviews with executives from a multinational industrial company. These interviews were transcribed, coded, and analyzed using a deductive data collection and analysis protocol, supported by NVivo software. Results: the presence of organizational silos and the absence of a digital strategy were identified as key issues that have impacted the transformation of the pre-digital business studied. These challenges were mapped not only through case study analysis but also by triangulating these findings with the existing literature. Conclusion: despite the integration of an emerging digital strategy into ITBSA, traditional practices can still be helpful to mitigate the identified issues of strategic misalignment and organizational silos. For instance, executives need to maintain a balanced focus on both intellectual and social alignments to ensure that IT, business, and digital strategies collectively enable the business operations and transformation.
Assessment of SONREB Models' performance in the in-situ estimation of compressive strength of carbonated concretes: a case study in Brazil
Authors: Santos Rodrigo Carvalho , Cardoso Sandra Carla Lima
Published: November 2024

Abstract The evaluation of compressive strength in existing concrete buildings poses an engineering challenge, stemming from the development of structural sizing techniques. In this context, the evolution of non-destructive testing equipment and methodologies has allowed for a deeper analysis of the properties of the concrete under study and a reduction in the number of core extraction tests, which are more invasive techniques. Among the various approaches to strength estimation, the emergence of combined methods like SONREB (ultrasonic pulse velocity and rebound number) has stood out due to the comprehensive nature of the properties considered. However, the scarcity of real-world case study data and the challenges of in-situ evaluation hinder the consolidation and subsequent dissemination of this method, especially in Brazil. Thus, the present case study in a 95-year-old building allows the assessment of the effectiveness of different methods in estimating the compressive strength of the tested elements and the overall structure. The obtained results highlight the importance of calibrating the models to the reality of the analyzed structure and considering the effects of carbonation. Furthermore, the analysis of these results reveals the need to evolve the method in order to universalize it, given the low performance of the tested models. Despite this, it is noteworthy that the estimated overall average strength of the building is very close to the actual value, with an absolute error of approximately 2 MPa and a relative error of 8.5%.
Cobertura vacinal completa de crianças nascidas em 2017-2018, residentes nas áreas urbanas das capitais e em 12 cidades do interior do Brasil, inquérito de base populacional baseado em uma coorte retrospectiva
Authors: Moraes José Cássio de , França Ana Paula , Guibu Ione Aquemi , Barata Rita Barradas , Domingues Carla Magda Allan Santos , Teixeira Maria da Gloria , Silva Adriana Ilha da , Ramos Jr. Alberto Novaes , França Ana Paula , Oliveira Andrea de Nazaré Marvão , Boing Antonio Fernando , Domingues Carla Magda Allan Santos , Oliveira Consuelo Silva de , Maciel Ethel Leonor Noia , Guibu Ione Aquemi , Mirabal Isabelle Ribeiro Barbosa , Barbosa Jaqueline Caracas , Lima Jaqueline Costa , Moraes José Cássio de , Luhm Karin Regina , Caetano Karlla Antonieta Amorim , Lima Luisa Helena de Oliveira , Antunes Maria Bernadete de Cerqueira , Teixeira Maria da Gloria , Teixeira Maria Denise de Castro , Borges Maria Fernanda de Sousa Oliveira , Queiroz Rejane Christine de Sousa , Gurgel Ricardo Queiroz , Barata Rita Barradas , Azevedo Roberta Nogueira Calandrini de , Oliveira Sandra Maria do Valle Leone de , Teles Sheila Araújo , Gama Silvana Granado Nogueira da , Mengue Sotero Serrate , Simões Taynãna César , Nascimento Valdir , Araújo Wildo Navegantes de
Published: November 2024

RESUMO Objetivo Estimar a cobertura vacinal em crianças nascidas entre 2017-2018, residentes nas áreas urbanas das capitais, do Distrito Federal e em 12 municípios do interior do Brasil, e identificar fatores associados. Métodos Inquérito domiciliar realizado entre 2020-2022, em crianças até 24 meses. Estimou-se a cobertura vacinal segundo características da família, da mãe e da criança. Resultados Nas 37.801 crianças da amostra, a cobertura completa (doses aplicadas) foi de 60,1% (IC95% 58,6;61,6), e 6,1% (IC95% 5,4;7,0) não receberam qualquer vacina. A cobertura foi menor em crianças de mães com menor instrução (OR = 0,70; IC95% 0,54;0,90) e nas que tinham atraso em qualquer vacina até os 6 meses de vida (OR = 0,28; IC95% 0,24;0,32). Conclusão As coberturas vacinais estão aquém do esperado. É necessário adotar estratégias de comunicação efetivas para reforçar a importância da vacinação de rotina, prevenindo atrasos e abandono do esquema vacinal, para retomar os altos níveis alcançados em décadas passadas.
Vaccination coverage, hesitancy and associated factors: a household survey of a cohort of children born in 2017 and 2018 in urban areas of state capital cities in the Brazilian Northeast
Authors: Saavedra Ramon da Costa , Santiago Martha Suely Itaparica de Carvalho , Teixeira Maria da Glória Lima Cruz , Antunes Maria Bernadete de Cerqueira , Queiroz Rejane Christine de Sousa , Lima Luisa Helena de Oliveira , Ramos Jr Alberto Novaes , Ferreira Anderson Fuentes , Maciel Adjoane Mauricio Silva , Barbosa Jaqueline Caracas , França Ana Paula , Domingues Carla Magda Allan Santos , Moraes José Cássio de , Silva Adriana Ilha da , Ramos Jr. Alberto Novaes , França Ana Paula , Oliveira Andrea de Nazaré Marvão , Boing Antonio Fernando , Domingues Carla Magda Allan Santos , Oliveira Consuelo Silva de , Maciel Ethel Leonor Noia , Guibu Ione Aquemi , Mirabal Isabelle Ribeiro Barbosa , Barbosa Jaqueline Caracas , Lima Jaqueline Costa , Moraes José Cássio de , Luhm Karin Regina , Caetano Karlla Antonieta Amorim , Lima Luisa Helena de Oliveira , Antunes Maria Bernadete de Cerqueira , Teixeira Maria da Glória Lima Cruz , Teixeira Maria Denise de Castro , Borges Maria Fernanda de Sousa Oliveira , Queiroz Rejane Christine de Sousa , Gurgel Ricardo Queiroz , Barata Rita Barradas , Azevedo Roberta Nogueira Calandrini de , Oliveira Sandra Maria do Valle Leone de , Teles Sheila Araújo , Gama Silvana Granado Nogueira da , Mengue Sotero Serrate , Simões Taynãna César , Nascimento Valdir , Araújo Wildo Navegantes de
Published: November 2024

ABSTRACT Objective To estimate vaccination coverage and analyze sociodemographic factors associated with non-vaccination in children born in 2017 and 2018 in the state capitals of Northeast Brazil. Methods A household survey using cluster sampling was conducted from 2020-2022 to estimate vaccination coverage and hesitancy. Factors associated with non-vaccination were analyzed using logistic regression to calculate Odds Ratios (OR) and their Confidence Intervals (95%CI). Results Natal was the capital with the lowest vaccination coverage, below 75.0% for most immunizers. Teresina had rates equal to or greater than 90.0% for all vaccines. Among those interviewed, 99.1% (95%CI 98.9;99.3) believe that vaccines are important for health; 95.4% (95%CI 95.0;95.8) trust immunobiologicals and 79.6% (95%CI% 78.8;80.3) are not afraid of reactions. Belonging to the highest socioeconomic stratum (adjusted OR: 1.34 – 95%CI 1.20;1.50) was as a factor associated with non-vaccination. Conclusion Low coverage highlights the need for a better understanding of regional specificities and social inequalities.
Cobertura, hesitação vacinal e fatores associados à não vacinação: inquérito domiciliar em coorte de crianças nascidas vivas em 2017 e 2018 em áreas urbanas de capitais do Nordeste brasileiro
Authors: Saavedra Ramon da Costa , Santiago Martha Suely Itaparica de Carvalho , Teixeira Maria da Glória Lima Cruz , Antunes Maria Bernadete de Cerqueira , Queiroz Rejane Christine de Sousa , Lima Luisa Helena de Oliveira , Ramos Jr Alberto Novaes , Ferreira Anderson Fuentes , Maciel Adjoane Mauricio Silva , Barbosa Jaqueline Caracas , França Ana Paula , Domingues Carla Magda Allan Santos , Moraes José Cássio de , Silva Adriana Ilha da , Ramos Jr. Alberto Novaes , França Ana Paula , Oliveira Andrea de Nazaré Marvão , Boing Antonio Fernando , Domingues Carla Magda Allan Santos , Oliveira Consuelo Silva de , Maciel Ethel Leonor Noia , Guibu Ione Aquemi , Mirabal Isabelle Ribeiro Barbosa , Barbosa Jaqueline Caracas , Lima Jaqueline Costa , Moraes José Cássio de , Luhm Karin Regina , Caetano Karlla Antonieta Amorim , Lima Luisa Helena de Oliveira , Antunes Maria Bernadete de Cerqueira , Teixeira Maria da Glória Lima Cruz , Teixeira Maria Denise de Castro , Borges Maria Fernanda de Sousa Oliveira , Queiroz Rejane Christine de Sousa , Gurgel Ricardo Queiroz , Barata Rita Barradas , Azevedo Roberta Nogueira Calandrini de , Oliveira Sandra Maria do Valle Leone de , Teles Sheila Araújo , Gama Silvana Granado Nogueira da , Mengue Sotero Serrate , Simões Taynãna César , Nascimento Valdir , Araújo Wildo Navegantes de
Published: November 2024

RESUMO Objetivo Estimar a cobertura vacinal e analisar fatores sociodemográficos associados à não vacinação em crianças nascidas vivas em 2017 e 2018 nas capitais do Nordeste brasileiro. Métodos Realizou-se inquérito domiciliar com amostragem por conglomerados, entre 2020 e 2022, para estimar cobertura e hesitação vacinal. Fatores associados à não vacinação foram analisados usando-se regressão logística para calcular odds ratio (OR) e seus intervalos de confiança (IC95%). Resultados A capital com menores coberturas vacinais foi Natal, com < 75,0% para a maioria dos imunizantes; Teresina apresentou coberturas ≥ 90,0% em todos os imunizantes. Dos entrevistados, 99,1% (IC95% 98,9;99,3) acreditavam que vacinas são importantes para a saúde; 95,4% (IC95% 95,0;95,8) confiavam nos imunobiológicos distribuídos pelo governo; e 79,6% (IC95% 78,8;80,3) não tinham medo de reações adversas. Residir em estrato socioeconômico mais alto (OR ajustado: 1,34 – IC95% 1,20;1,50) foi fator associado à não vacinação. Conclusão As baixas coberturas destacam a necessidade de entender melhor as especificidades regionais e as desigualdades sociais.
EXPERIMENTAL STUDY OF THE ATOMIZATION OF SEMICRYOGENIC JET IMPINGEMENT
Authors: Moosavian Davood , Ghassemi Hojat
Published: November 2024

The behavior of unlike jet impingement for use as an atomizer was explored experimentally in this study. Water jets with different speeds and liquid nitrogen/methanol unlike jets produced by needle injectors were employed in this study. Short exposure photography was utilized to study the various models that emerged from this interaction. The jets' speed was increased from 3 to 30 m/s. The impact
speed range of the formation of closed rim, periodic rim, open rim, and fully developed sheet models was
identified by qualitatively comparing images of unlike water jet impingement. Clear and predictable patterns appear around the impact point when water jets impinge. The creation of the gas phase at the impinging point of liquid nitrogen and methanol jets causes disruptions on the liquid sheet. The combination of these disturbances and collision waves causes the liquid sheet to break up faster. Furthermore, unlike the water sheet, the waves on the methanol/liquid nitrogen sheet do not form regular concentric sectors due to the evaporation of liquid nitrogen at the collision point of two jets. The diameter of the
droplets resulting from the impingement, with the increase of the collision speed, is greatly reduced and
tends to a constant value asymptotically. Methanol and nitrogen droplets are also generated individually
in this type of impingement. Droplets of methanol are significantly larger than droplets of nitrogen.
Transforming the Vocabulaire de la Sigillographie into a Semantic Web Resource
Authors: Vogeler Georg
Published: November 2024

This paper describes the current situation in the area of digital sigillography that focuses on creating data sets. It observes the possibility of aligning these data sets and suggests developing the Vocabulaire Internationale de la Sigillographie (created in 1990) further for this purpose. It presents the conversion of the printed version into an SKOS (Simple Knowledge Organisation System) resource. It highlights the opportunities offered by Semantic Web technologies, which can begin with sharing descriptive vocabularies. Data interchange between the various European sigillographic resources can be further promoted by shared semantics. This paper proposes a CIDOC-CRM-compliant OWL ontology built on top of the VIS. This is organized around the events of creating the matrix, applying the matrix, handling the impression (e.g., destroying, cutting off), conservation and description. The proposed basic entities map well to existing major seal databases, with the effect that the French Sigilla and the British DigiSig database could merge, and a common European database of medieval seals seems possible.
Cet article décrit la situation actuelle dans le domaine de la sigillographie numérique, qui se concentre sur la création de jeux de données. Il examine la possibilité d’aligner ces jeux de données et propose de développer davantage le Vocabulaire International de la Sigillographie (créé en 1990) à cette fin. Il présente la conversion de la version imprimée en une ressource SKOS (Simple Knowledge Organisation System). Il met en évidence les opportunités offertes par les technologies du Web sémantique, qui peuvent commencer par le partage de vocabulaires descriptifs. L’échange de données entre les différentes ressources sigillographiques européennes peut être davantage favorisé par des sémantiques partagées. Cet article propose une ontologie OWL conforme au CIDOC-CRM construite sur le VIS. Celle-ci est organisée autour des événements de création de la matrice, d’application de la matrice, de gestion de l’impression (par exemple, destruction, découpage), de conservation et de description. Les entités de base proposées correspondent bien aux principales bases de données de sceaux existantes, avec pour effet que le Sigilla français et la base de données britannique DigiSig pourraient fusionner, et qu’une base de données européenne commune des sceaux médiévaux semble possible.
Factors associated with the development, severity, and resolution of post COVID-19 condition in adults living in Canada, January 2020 to August 2022
Authors: Zakaria Dianne , Demers Alain , Cheta Nicholas , Aziz Samina , Abdullah Peri
Published: November 2024

Objectives

We aimed to characterize the burden of post COVID-19 condition (PCC) among adults in Canada and identify factors associated with its occurrence, severity, and resolution.

Methods

We used self-report data from a population-based cross-sectional probability survey of adults in Canada conducted between April and August 2022. Incidence and prevalence of PCC were estimated using confirmed infections, as well as confirmed and suspected combined. Multivariable modeling using confirmed cases identified associated factors.

Results

As of August 2022, 17.2% (95% CI 15.7, 18.8) of adults with confirmed infections and 16.7% (95% CI 15.5, 18.0) of adults with confirmed or suspected infections experienced PCC, translating to 3.3% (95% CI 3.0, 3.6) and 4.4% (95% CI 4.1, 4.8) of all adults, respectively. Age less than 65 years (aORs of 1.75 to 2.14), more pre-existing comorbidities (aORs of 1.75 to 3.57), and a more severe initial infection (aORs of 3.52 to 9.69) were all associated with higher odds of PCC, while male sex at birth (aOR = 0.54, 95% CI 0.41, 0.70), identifying as Black (aOR = 0.23, 95% CI 0.11, 0.51), and being infected after 2020 (aORs of 0.24 to 0.55) were associated with lower odds. Those residing in a rural area (aOR = 2.31, 95% CI 1.35, 3.93), or reporting a disability (aOR = 2.87, 95% CI 1.14, 7.25), pre-existing chronic lung condition (aOR = 5.47, 95% CI 1.85, 16.12) or back problem (aOR = 2.34, 95% CI 1.26, 4.36), or PCC headache (aOR = 2.47, 95% CI 1.60, 3.83) or weakness (aOR = 2.27, 95% CI 1.41, 3.68) had higher odds of greater limitations in daily activities, while males had lower odds (aOR = 0.54, 95% CI 0.34, 0.85). Two or more pre-existing chronic conditions (aHRs from 0.33 to 0.38), or PCC symptoms relating to the heart (aHR = 0.25, 95% CI 0.07, 0.90), brain fog (aHR = 0.44, 95% CI 0.23, 0.86), or stress/anxiety (aHR = 0.48, 95% CI 0.24, 0.96) were associated with a decreased rate of symptom resolution.

Conclusion

Over the first two and a half years of the pandemic, a substantial proportion of infected adults in Canada reported PCC. Females and people with comorbidities were disproportionately impacted.
Fosforik asit emdirilmiş viskoz rayon liflerinin karbonizasyon öncesi termal stabilizasyon aşamasında meydana gelen yapısal dönüşümlerin incelenmesi
Authors: Gül Abdullah
Published: November 2024

Bu çalışmada, rejenere selüloz liflerinden olan viskoz rayon lifinin karbonizasyon aşaması öncesinde termal stabilizasyon sırasında meydana gelen yapısal değişimleri incelenmiştir. Viskoz rayon lifleri, oda sıcaklığında %4’lük sulu fosforik asit (FA) çözeltisi içerisinde 30 dk. kimyasal ön işleme tabi tutulmasının ardından, ön kurutma işlemi ve farklı stabilizasyon (oksidasyon) sıcaklıklarında (150-175-200-225 ve 250°C) ısıl işleme alınmıştır. Termal stabilizasyon sonrasında numuneler üzerinde; iplik numara ölçümü, renk değişim analizi, yoğunluk, mikroskop lif kalınlık çalışması ve iplik mukavemeti gibi birtakım fiziksel ve yapısal özelliklerdeki değişimler incelenmiştir. Bununla birlikte numunelerin yapısal karakterizasyon kombinasyonu için yakma testi, SEM, diferansiyel taramalı kalorimetri (DSC), termogravimetrik analiz (TGA) ve kızılötesi (FTIR) spektroskopi ölçümleri ve mekanik testler yapılmıştır. Termal stabilizasyon işlem sıcaklığının artmasına bağlı olarak iplik numarası ve lif kalınlığı değerlerinin azaldığı saptanmıştır. Bununla birlikte termal stabilizasyon işlemlerinden sonra viskoz rayon numunelerinin görüntüsü beyaz renkten karbon siyahına doğru değişirken, 225 ve 250 °C’de ısıl işlem gören numuneler yanmazlık özelliği kazanmıştır. Yapılan mukavemet analizlerinde 225 °C’lik stabilizasyon sıcaklığına kadar çekme dayanımı ve kopma uzaması değerleri azalırken 250 °C’lik stabilizasyon işleminden sonra bu değerlerde kısmen artış gözlenmiştir. Stabilizasyon sıcaklığına bağlı olarak, sıcaklık arttıkça stabilizasyon numunelerinin kristal yapısındaki değişimler sebebiyle bozunma endotermi azalmış ve 250 °C’lik ısıl işlem sonrasında neredeyse kaybolmuştur.
REABILITAÇÃO MORFOFUNCIONAL DE DENTES DECÍDUOS ANTERIORES EM CRIANÇA COM DISPLASIA ECTODÉRMICA: RELATO DE CASO CLÍNICO
Authors: Junior Paulo Bisi dos Santos , Silva Conceição de Maria Sales da , Costa Natacha Malu Miranda da , Valente Raissa Baia
Published: October 2024

A displasia ectodérmica (DE) é uma condição genética rara que afeta o desenvolvimento de estruturas originadas do ectoderma, incluindo pele, cabelo, unhas e dentes. Em pacientes com DE, é comum encontrar dentes em formato conóide, hipodontia ou anodontia, além de alterações na salivação e dificuldades sociais devido à aparência facial e dentária. O diagnóstico precoce é essencial para minimizar impactos funcionais e emocionais. Assim, o relato de caso desse artigo descreve a reabilitação de uma criança com DE realizada na clínica-escola da Universidade Federal do Pará (UFPA). O paciente, J.M.S., um menino de quatro anos, apresentava timidez e queixas de "bullying" na escola por conta de seus dentes pontiagudos. No exame clínico, foram identificados cabelos finos, pele seca, nariz em sela e microdontia dos dentes decíduos, além da ausência congênita de um incisivo lateral. O diagnóstico foi confirmado pelo Serviço de Genética da UFPA, que identificou a forma hipohidrótica da DE. A reabilitação proposta envolveu técnicas de resina composta para devolver a funcionalidade e a estética dos dentes. O tratamento iniciou-se com adequação do meio bucal, controle do biofilme e escolha da cor da resina. A técnica com coroas de acetato foi aplicada em dentes superiores, enquanto a técnica de modelagem direta (mão livre) foi usada nos dentes inferiores. A resina composta foi polimerizada e ajustada para garantir a integridade oclusal e estética. Após o procedimento, o paciente relatou melhora significativa na autoestima e no convívio social, além de maior conforto ao mastigar alimentos. Como conclusão, esse caso reforça a importância da reabilitação precoce em crianças com DE para restaurar as funções fonética e mastigatória e promover bem-estar emocional. A abordagem multidisciplinar, envolvendo dentistas, ortodontistas e outros profissionais, é fundamental para garantir o acompanhamento contínuo e uma melhor qualidade de vida. O uso de técnicas conservadoras, como resinas compostas, demonstrou ser eficaz na recuperação estética e funcional de dentes decíduos afetados pela displasia ectodérmica.
How Much We Know about Dolicoarteriopathies
Authors: Mehmet Erkan Üstün , Baylar Baylarov
Published: November 2024

Vertebral and carotid artery dolicoarteriopathies, including elongation, kinking, and coiling, are linked to various cerebrovascular dysfunctions. Kinking, categorized by Metz, et al. is graded by angle severity: Grade 1 (90° - 60°), Grade 2 (60° - 30°), and Grade 3 (< 30°). In Grades 2 and 3, reduced blood flow heightens ischemic risk, contributing to hemodynamic instability and cerebrovascular insufficiency. While most symptomatic cases undergo endovascular or surgical correction, some patients with severe kinking remain asymptomatic, questioning current understanding. In 150 cases of carotid or vertebral artery kinking, we observed stenosis in symptomatic patients, differing from the expected arterial enlargement seen in dolicoarteriopathies. This suggests two potential kinking types: stenotic and enlarged. A notable case presented bilateral Grade 3 internal carotid artery kinking, with right-sided stenosis and cerebral hypoperfusion, yet left-sided transient ischemic attacks occurred. This finding challenges existing classifications and suggests further investigation is warranted.
Assessment of humoral immunity to the measles virus in healthcare workers
Authors: Eremeeva Zhanna G. , Ardabatskaya Elena S. , Ardabatsky Sergey A. , Iskandarov Ildar R. , Ilyina N V , Levchenko Kseniya G. , Ivanova Yekatherina O. , Bogdanova Elena V. , Valiev Rushan I.
Published: November 2024

BACKGROUND: measles is an anthroponotic viral disease characterized by high contagiousness. In the early 2000s in the Russian Federation, the infection was on the verge of elimination, but outbreaks in 2003, 2014, 2019 and the rise in incidence since 2022 refutes this situation. Cleanup vaccination of risk groups and revaccination of persons vaccinated once are ongoing. It is relevant to determine antibodies in blood serum in the vaccinated population and in persons with an unknown vaccination and post-infection history.
AIM: of the study is to present the results of a study of humoral immunity to the measles virus in healthcare workers vaccinated against measles and with an unknown vaccination and post-infectious history.
MATERIALS AND METHODS: the study was conducted in Kazan, Republic of Tatarstan. The study involved employees of a skin and venereal disease clinic, children's clinics, and a blood center in the amount of 133 people (including 2 men), who were vaccinated and revaccinated with live measles vaccine, after which a sufficient amount of time had passed for the formation of an immune response - 3-4 weeks, as well as 40 female employees with an unknown vaccination and post-infection history. Specific IgG to the measles virus was determined in the test blood sera using the enzyme immunoassay method using the Vector-Best kit (Novosibirsk, Russia). Statistical analysis was carried out using the StatTech v.4.1.9 program (developed by Stattech LLC, Russia).
RESULTS. The study was conducted in Kazan, Republic of Tatarstan. The study involved employees of a skin and venereal disease clinic, children's clinics, and a blood center in the amount of 133 people (including 2 men), who were vaccinated and revaccinated with live measles vaccine, after which a sufficient amount of time had passed for the formation of an immune response - 3-4 weeks, as well as 40 female employees with an unknown vaccination and post-infection history. Specific IgG to the measles virus was determined in the test blood sera using the enzyme immunoassay method using the Vector-Best kit (Novosibirsk, Russia). Statistical analysis was carried out using the StatTech v.4.1.9 program (developed by Stattech LLC, Russia).
CONCLUSIONS. The ongoing outbreaks of measles in 2003, 2014, 2019, 2022-2023 require constant monitoring of the epidemiological situation with the study of the post-vaccination immune response in vaccinated people and the post-infection response in people with an unknown history of measles
Kur’an’da Tekrarlı Anlatımlarda Kullanılan Bazı Kelimelere Terâdüf ve Furûk Açısından Bir Yaklaşım
Authors: Yılmaz Kerim
Published: November 2024

Kur’an’da bazı olayların anlatımında konuya dikkat çekmen için tekrarlı anlatım yöntemi kullanılmaktadır. Tekrarlarda aynı olayların veya birbirine benzer hadiselerin anlatımı esnasında farklı kelimelerin kullanıldığı müşahede edilmektedir. Çalışmanın amacı, Kur’an’da tekrarlı anlatımlarda kullanılan bazı kelimeleri geçmişten günümüze tartışıla gelen terâdüf ve furûk açısından incelemektir. Bu amaç doğrultusunda örneklem olarak inbecese-infecera, veled-ġulâm ve baḥr-yemm kelimeleri seçilmiştir. Seçilen örneklemler doğrultusunda ilgili kelimelerin etimolojisini, cahiliye döneminde ve Kur’an’daki kullanımlarını genel anlamda inceledikten sonra terâdüf ve furûk olgusu açısından ele alınması çalışmanın sınırlarını oluşturmaktadır. Sonuç olarak verilen örnekler Kur’an’ı anlamada önemli bir faktör olan furûk olgusunun Kur’an’daki bütün kelimelere uygulandığında zaman zaman zorlama yorumlara sebep olabileceğini göstermektedir. Benzer bir şekilde terâdüf olgusunun da furûk olgusunu dikkate almadan bütün ayetlere uygulanmaya çalışılması da hatalı yorumlara sebep olabilir.
Statistical and Machine Learning Contributions to the Analysis of Single-Cell RNA Sequencing Data
Authors:   , Cui Saishi , Nassiri Sina , Zakeri Issa
Published: November 2024

Single-cell RNA sequencing (scRNA-seq) has become widely adopted as a powerful technology enabling whole transcriptome profiling of individual cells. Nevertheless, the intricate handling of the scRNA-seq data necessitates specific computational approaches. In this dissertation, I proposed novel statistical or machine learning solutions to address existing bottlenecks in three key aspects of analyzing scRNA-seq data. 1) Feature selection: In the first part of my dissertation, I introduced a framework that integrates Multiple Correspondence Analysis, graph-based community detection, and a new statistical test to improve the identification of highly variable genes, unlocking downstream analyses of scRNA-seq data; 2) Cell type annotation: In the second part, I developed an ensemble learning framework that enhances the precision of automated cell type annotation based on an oversampling strategy and compositional data transformation, addressing the inherent imbalance of cell type proportions within biological samples, and the compositional nature of sequencing-based gene expression quantification. 3) Trajectory-based functional gene set testing: In the last part, leveraging ideas from Functional Data Analysis - a branch of statistics dealing with data sets consisting of functions, curves, or trajectories - I developed a new method for piecewise functional two-sample testing of gene sets, enabling statistical comparison of a group of genes across the developmental progression or differentiation status of individual cells within a biological sample. Collectively, this dissertation makes significant contributions in the field by introducing innovative statistical or machine learning approaches to tackle current limitations in three fundamental aspects of analyzing scRNA-seq data.
Therapeutic Advancements in Anemia of Chronic Kidney Disease and End Stage Kidney Disease
Authors: Sharma Neeraj , Gay Marcus , Tawadrous Marina , Lin Tracy
Published: November 2024

Anemia is a frequent complication during the late stages of chronic kidney disease, reaching an almost universal prevalence among those with end stage kidney disease. There is a clear association between anemia and an increased risk for decline in the estimated glomerular filtration rate, cardiovascular events, and all-cause mortality. The main mechanisms for the development of anemia related to chronic kidney disease are a relative erythropoietin deficiency and disordered iron homeostasis related to chronic inflammation. Recent improvements in the understanding of the pathophysiology of anemia in chronic kidney disease have advanced the diagnosis and treatment of anemia in chronic kidney disease. While the cornerstone of the diagnosis of anemia related to chronic kidney disease remains excluding other etiologies of anemia, newer diagnostic resources include population-informed cutoffs for traditional measures of iron storage as well as evolving diagnostics of the reticulocyte hemoglobin index and percent hypochromic red blood cells in plasma. Intravenous iron has emerged as a novel tool for both the diagnosis and treatment of disordered iron homeostasis in the anemia of chronic kidney disease. Outside of iron replacement, the treatment of the anemia of chronic kidney disease has traditionally relied on erythropoiesis stimulating agents. A newer class of medications, the Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors, are an emerging therapy that work by stimulating the transcription of the erythropoietin gene in the Kidney and Liver. These agents are oral therapy, unlike erythropoiesis-stimulating agents, and are used in those who fail to respond to traditional therapy. Additional novel and experimental therapies include SGLT2 inhibitors, inhibitors of hepcidin production, and novel oral and intravenous iron formulations. This review encompasses the highlights of the epidemiology, pathophysiology, and the recent diagnostic and therapeutic advancements for anemia in chronic kidney disease.
Impact of Trade Wars on the Global Economy and on the Macroeconomic and Sectoral Indicators of the USA and China
Authors: Knobel A. Yu. , Ponomareva O. V. , Sedalishchev V. V.
Published: November 2024

The trade war initiated by the United States against some of its trading partners from 2017 to 2019 has become a crucial factor in the current transformation of the global economy. The main confrontation unfolded between the US and China, as the imposition of high tariff barriers on a wide range of goods in bilateral trade led to the contraction of trade flows. Technological rivalry between the two countries also fed the trade war that has now become a central aspect of the ongoing US-China economic conflict. The article examines the content and scope of the US trade war restrictions and the retaliation against them by other countries; and it provides an overview of specific empirical studies that trace out the consequences of these measures for the global economy and individual countries. The authors use a general equilibrium model to simulate the effects of the trade war at both the macroeconomic and sectoral levels. The primary markets analyzed are those of the US and China because their economies are the most deeply involved in the conflict. The modeling indicates that the tariff restrictions on bilateral trade have adverse effects on the GDP of both the US and China, and the majority of sectoral-level indicators are also negative. The positive effects on certain industrial sectors are due to less dependency on imports or exports subject to increased duties or to options for quickly redirecting trade flows to alternative suppliers and customers. The resulting partial reorientation of trade has had positive effects on other countries that are trading partners with the US and China. In the long term, the unwavering policy of technological decoupling between the US and Chinese economies is the most significant factor in the future course of their interactions. Both countries are trying to exclude the most sensitive technologies from economic cooperation and tend to impose non-tariff measures such as export controls more frequently than tariffs.
The Role of Fiscal Policy in Ensuring the Financial and Technological Sovereignty of the Country
Authors: Siluanov A. G.
Published: November 2024

Financial and technological sovereignty is becoming an important driver of the economic transformation in response to current trends toward regionalization, disruption of value chains, and non-market trade and financial restrictions. Fiscal and financial policies that promote macroeconomic stability and unencumbered operation of economic mechanisms can be considered key components of a country’s financial sovereignty. This article concentrates on analysis of the reforms carried out in Russia over the previous ten years. These reforms have facilitated creation of one of the world’s most effective state budget systems, reduction of dependence on oil price volatility, and enhancement of countercyclicality. Revising budget rules and increasing the efficiency of the fiscal system, including tax administration, were the key decisions that enabled these changes. The importance of the reforms has been confirmed by their success in counteracting the consequences of the COVID-19 pandemic and the pressure from unprecedented sanctions while also ensuring rapid changes in the structure of Russia’s economy. During the crisis period, the principal ways of implementing budget policy adhered to four main principles: maintaining due proportionality of budget support to the scale of shocks, targeting support, holding fast to strategic objectives, and encouraging structural transformations. This article addresses the new challenges ahead by outlining a medium-term development model for the Russian economy. This model envisions establishment of the conditions essential for technological advancement. It also highlights the role of fiscal and financial policy instruments in creating long-term financing sources, offering tax incentives, and providing targeted support measures throughout various stages of the technological cycle. The importance of continuing efforts to develop an independent financial and payment infrastructure aimed at facilitating free foreign economic activity is also emphasized.
Reflexões sobre descentralização do SUS e o direito à saúde
Authors: Tavares Amaral Isabela Barboza da Silva
Published: November 2024

Objetivo: O objetivo do presente ensaio teórico é desvelar se existe uma interface associativa entre a descentralização do SUS e a efetivação do direito à saúde no Brasil. Método: O presente ensaio deriva de reflexões tecidas no desenvolvimento da etapa teórica de uma Tese de Doutorado, que buscou analisar um estudo de caso acerca de uma experiência entre instituições políticas e jurídica. Resultados: Há uma complexidade de contextos históricos e fatores sociais que configuram o direito à saúde como um fenômeno social, que, embora forjado em robusto arcabouço jurídico, na prática, nem sempre corresponde àquilo que se cristalizou enquanto norma. Entende-se que, para o contexto brasileiro, a descentralização por si só como uma diretriz organizativa da gestão do SUS, visando à municipalização dos serviços sem o provimento das condições adequadas para tal, pode inclusive incrementar os desafios postos à efetivação do direito à saúde no Brasil. Considerações finais: É preciso encontrar meios de fortalecimento da gestão pública municipal e estadual, incluindo a possibilidade de aumento dos gastos no setor saúde, ao contrário da opção estatal legitimada na EC 95. De outra forma, a descentralização nunca evidenciará a potência do controle social e da capacidade de uma gestão local fortalecida em um contexto tão heterogêneo de distribuição de recursos e permeado pelas heranças dos “ismos” que remontam a história da formação da burocracia pública no Brasil. São necessárias contribuições científicas que possam nortear ações político-institucionais que tornem a saúde um direito constitucional a ser priorizado.
Por que o sarampo voltou ao Brasil após erradicação em 2016? Razões para o regresso do patógeno ao país
Authors: Henrique Ferri Milena , Lazzaretti Camilla
Published: November 2024

Introdução: Vacinas são métodos profiláticos, pois conferem imunidade após exposição a determinados antígenos. Tal método pode auxiliar na erradicação de doenças, assim como o Sarampo (SAP) entre os anos de 2017 e 2018. Objetivo: O objetivo do presente trabalho é identificar o número de casos atuais de SAP dos anos de 2014 a 2022, bem como os prováveis motivos do retorno do patógeno ao Brasil. Metodologia: O estudo é uma revisão narrativa da literatura, por meio das bases de dados: Biblioteca Virtual em Saúde; SciELO; Lilacs;  Pubmed; e boletins epidemiológicos nacionais. Os descritores utilizados foram: “vacinas, movimento antivacinação, imunização, cobertura vacinal, recusa da vacina e sarampo”. Foram inseridos no estudo 31 artigos e/ou documentos. Resultados: Em 2018 ocorreram 10.330 casos de SAP no país e em 2019, até o mês de setembro, notificou-se 3.729 registros. O principal motivo para o retorno deste patógeno foi a queda da cobertura vacinal e esta é levada por inúmeras razões: (i) desinformação; (ii) situação sociocultural da população; (iii) condições socioeconômicas; (iv) baixa escolaridade; (v)  falhas governamentais de políticas; (vi) imigração de países próximos (vii) questões demográficas. Conclusão: Observa-se a relevância de enfatizar para a população a importância da vacinação, por meio de políticas de saúde pública. Desta forma, o Brasil poderá diminuir o número de casos e buscar a certificação de erradicação.
Химия газофазного горения и сажеобразования
Authors: Мансуров З.А.
Published: November 2024

Данная статья посвящается памяти учителя, профессора, академика АТН Г.И. Ксандопуло. Ниже представлены обзор работ по изучению структуры фронта углеводородных пламен, выполнены под руководством Г.И. Ксандопуло, а также данные по исследованию образования фуллеренов и углеродных нанотрубок при горении углеводородов, полученные в Институте проблем горения в последнее время. В статье проведен обзор работ автора по изучению структуры фронта холодных пламен диэтилового эфира и бутана, предпламенной зоны нормальных пламен пропана и сажеобразованию при горении углеводородов. Рассмотрены феноменология, кинетика и механизм сажеобразования, влияние различных факторов на образование полициклических ароматических углеводородов (ПЦАУ), углеродных нанотрубок, фуллеренов, графенов и сажи.• Низкотемпературная зона фронта углеводородных пламен• Холодные пламена• Неизотермические холодные пламена диэтилового эфира• Обнаружение атомов водорода и их распределение во фронте стабилизированных холодных пламен углеводородов • Синтез углеродных нанотрубок в режиме горения • Сажеобразование при горении метана в электрическом поле• Новые наноуглеродные энергоемкие материалы
Электропроводящие герметизирующие силиконовые композиции, наполненные углеродными материалами
Authors: Тулепов М.И. , Мышырова Ж.К. , Бускетс Р. , Азат С. , Сасыкова Л. , Турешова Г.О. , Рахимова Б.У. , Жапекова А.О. , Спанова Г.А.
Published: November 2024

Электропроводящие герметики и покрытия представляют большой интерес в последние годы в связи с развитием электроники и технологий. В данной области ведется множество исследований по изучению электропроводящих свойств композитов, наполненных различными углеродными материалами. Однако существует не так много исследований, где используются силоксаны в качестве матриц. Целью данной работы явилось получение недорогого электропроводящего композита с использованием силиконовой матрицы и углеродных наполнителей: технического углерода, графита, угля. Наилучшим наполнителем для электропроводящего герметика послужил технический углерод (30 масс.%), продемонстрировавший электропроводимость 1,11×102 (Ом×м)–1. Однако увеличение содержания технического углерода в матрице отрицательно сказалось на физико-механических свойствах, условная прочность при разрыве уменьшилась на 42%, относительное удлинение при разрыве на 37%. Полученный композит можно использовать в качестве  электропроводящего герметизирующего материала, однако при необходимости сохраняется улучшения физико-механических характеристик.
Institutional Agents: A Significant Facilitator of the Advancement of Women Leaders
Authors: Proff Alexandria , Musalam Rasha
Published: November 2024

Research on women's employment in the Arab world has highlighted a scarcity of women in senior leadership positions, often suggesting cultural conservatism and embedded gender-segregation within organizational structures. While these perspectives are not unfounded, these views may not fully capture the varied lived experiences of women leaders in the Arabian Gulf, particularly in the UAE. This study examined the influence of institutional agents on the career advancement of women leaders. The authors employed a phenomenological approach to explore the professional experiences of highly educated, women Arab leaders. The focus was specifically on their perceptions of gender discrimination, networking opportunities, and access to institutional agents. A sample population was purposefully identified; as such these findings may not be generalizable to the broader population. Data were collected via open-ended interviews and analyzed through multiple stages of coding stages using Atlas.ti. The results of this study present certain contradictory evidence to the existing literature. Notably, the women in this sample reported that gender discrimination was not a significant barrier to their career advancement. Further, the institutional agents most frequently identified by this sample of women were men. These findings suggest emerging narratives of a more gender-inclusive work culture. Moreover, these results offer a unique perspective that UAE professional environments may be more inclusive than previously reported. The findings of this study suggest that a more educated and diverse workforce could be contributing to a more inclusive atmosphere, challenging traditional views of workplace dynamics in the region.