bluuebunny/crossref_metadata_2025 huggingface dataset:
Racismo dentro das Escolas: Saúde Mental das Crianças Racializadas e Estratégias de Enfrentamento
Authors: Silva Daynara Mayany da , Oliveira Débora Benício Alves , Alves Francisca Ivoneide Benício Malaquias , Bringel Maricélia Félix Andrade
Published: November 2024

Esse estudo busca compreender como a discriminação continua desenvolvendo problemas como ansiedade, depressão e baixa autoestima, além de propor estratégias de enfrentamento que possam ser implementadas no ambiente escolar para mitigar esses efeitos. A pesquisa se desenvolve com base em uma metodologia qualitativa explicativa e utiliza histórias e exemplos práticos para contextualizar o tema de forma acessível. A partir da análise, constata-se que a adoção de práticas educacionais inclusivas e políticas antirracistas pode promover um ambiente escolar mais acolhedor e equitativo, reduzindo os impactos negativos do racismo na saúde mental e emocional das crianças racializadas. Conclui-se que o enfrentamento eficaz do racismo nas escolas é essencial para o desenvolvimento saudável dessas crianças e para a construção de um espaço educativo mais justo e inclusivo. Esse enfrentamento exige um compromisso contínuo de toda a comunidade escolar, com ações que vão desde a capacitação de educadores até a criação de ambientes que promovam o diálogo e a representatividade.
Isolation, identification, characterization and in vitro assay of saline tolerant endophytes against groundnut root rot caused by Rhizoctonia bataticola (Taub.) Butler
Authors: Aarthi R , Devanathan M , Harish S , Ganesan K N , Manivannan V
Published: November 2024

Groundnut, known as Arachis hypogaea L., is India's significant oil seed crop. Dry root rot, caused by Rhizoctonia bataticola, poses a substantial challenge to cultivating groundnuts. During the roving survey, 60.50% dry root rot disease incidence was recorded in Namakkal district, Tamil Nadu. This study aims to acquire salt-tolerant endophytic bacteria residing in groundnuts with significant antagonistic activity against R. bataticola. A total of 27 bacterial strains were isolated from groundnuts. Among these strains, RMV 3 and RMV 2 are the most effective isolates, exhibiting 60.1% and 50% inhibition zones, respectively. The effective isolates were characterized through morphological, biochemical and phytostimulation activities and 16S rDNA sequencing. Among the isolates, RMV 3 and RMV 2 showed positive results for siderophore, indole acetic acid (IAA) and cellulase test. The strain RMV 3 was identified as Bacillus subtilis through 16S rDNA sequencing. GC-MS analysis identified twenty bioactive compounds produced by B. subtilis RMV 3, such as pyrrolo [12-a] pyrazine-14-dione hexahydro-3 (2-methylpropyl) and hexadecanoic acid methyl ester. The crude metabolite assay demonstrated a 96.6% inhibition of R. bataticola by RMV 3. This study demonstrated that Bacillus subtilis RMV 3, which exhibits a robust antagonistic effect on R. bataticola, can potentially be an effective biocontrol agent for groundnut dry root rot.
International trade in food and agro-based products in the time of COVID-19
Authors: Gombkötő Nóra , Mezei Katalin
Published: November 2024

The aim of the study is to examine the regional impact of the COVID-19 pandemic and its individual waves on foreign trade in food and agro-based products in the world’s largest trading countries. The study was based on the statistical database of the International Trade Centre (ITC). In addition to the basic analysis, use was made of the auto- correlation method to detect special relationships between foreign food trade of different countries. The results show that the pandemic has had the greatest impact on agricultural and food trade in the United States, but it has spilled over to other countries as well, especially its two major trading partners, the European Union and China. Food trade stagnated in the initial period of the pandemic, but later recovered relatively well. The six examined regions can be divided into three groups based on the typical features of their autocorrelation.
Medical Insurance Contribution and Firm-Level Total Factor Productivity
Authors: Huang Tao , Sun Rui , Zhao Zhe
Published: November 2024

This paper investigates the relation between medical insurance contribution and firm-level total factor productivity in China. Using a sample of Chinese A-share companies from 2007 to 2022, we find robust evidence that firms exhibit lower total factor productivity when medical insurance contribution is increasing. Specifically, we also show that this negative effect is more profound for state-owned enterprises, enterprises with lower employee compensation, and labor-intensive enterprises. Meanwhile, our findings remain valid after a series of robustness tests and controlling for endogeneity. Finally, we propose that the decreasing employees’ disposable income is plausible channel through which medical insurance contribution discourages firm-level total factor productivity in China. Overall, these results shed light on the real effects of medical insurance contribution and the determinants of firm-level total factor productivity.
Cross Ownership Under Strategic Tax Policy
Authors: Can Gökhan , Mukherjee Arijit
Published: November 2024

We provide a new reason for the consumer surplus and welfare raising cross ownership. We show that cross ownership reduces the tax rate, and increases consumer surplus and welfare under Cournot and Bertrand competition when the marginal social cost/benefit of public funds is less than unity. We further show that Cournot competition creates higher consumer surplus and welfare compared to Bertrand competition if the marginal social cost/benefit of public funds is less than unity, thus providing a new reason for the Cournot-Bertrand welfare reversal.
Roseolithon mirabile (Foslie) comb. nov. (Hapalidiales, Corallinophycidae, Rhodophyta) based on DNA sequencing of the Archaeolithothamnion mirabile lectotype
Authors: Gabrielson Paul W. , Lamb Jeremy J. , Hughey Jeffery R.
Published: November 2024

Lithothamnion
mirabile is currently considered a heterotypic synonym of L. muelleri. Three of the 14 specimens and additional fragments comprising the holotype of L. mirabile were selected for DNA sequencing as they best matched the protologue. The three 263-base pair rbcL sequences were distinct from each other, and were classified in the order Hapalidiales, but none were resolved in Lithothamnion. One sequenced specimen belongs in Roseolithon and was selected as the lectotype; thus we propose R. mirabile (Foslie) comb. nov. Another sequenced specimen groups with Phymatolithopsis and the third is well resolved in an undescribed genus of Hapalidiales sister to Boreolithothamnion.
Stochastic dissipative Euler’s equations for a free body
Authors: de la Torre Jaime Arturo , Sánchez-Rodríguez Jesús , Español Pep
Published: November 2024

Intrinsic thermal fluctuations within a real solid challenge the rigid body assumption that is central to Euler’s equations for the motion of a free body. Recently, we have introduced a dissipative and stochastic version of Euler’s equations in a thermodynamically consistent way (European Journal of Mechanics – A/Solids 103, 105,184 (2024)). This framework describes the evolution of both orientation and shape of a free body, incorporating internal thermal fluctuations and their concomitant dissipative mechanisms. In the present work, we demonstrate that, in the absence of angular momentum, the theory predicts that the principal axes unit vectors of a body undergo an anisotropic Brownian motion on the unit sphere, with the anisotropy arising from the body’s varying moments of inertia. The resulting equilibrium time correlation function of the principal eigenvectors decays exponentially. This theoretical prediction is confirmed in molecular dynamics simulations of small bodies. The comparison of theory and equilibrium MD simulations allow us to measure the orientational diffusion tensor. We then use this information in the Stochastic Dissipative Euler’s Equations, to describe a non-equilibrium situation of a body spinning around the unstable intermediate axis. The agreement between theory and simulations is excellent, offering a validation of the theoretical framework.
VS-LTGARCHX: A Flexible Variable Selection in Log-TGARCHX Models
Authors: Orujov Samir , Elvira Victor , Poterie Audrey , Rajabov Farid , Septier Francois
Published: November 2024

The log-TGARCHX model is less restrictive in terms of the inclusion of exogenous variables and asymmetry lags compared to the GARCHX model. Nevertheless, adding less (or more) covariates than necessary may lead to under- or overfitting, respectively. In this context, we propose a new algorithm, called VS-LTGARCHX, which incorporates a variable selection procedure into the log-TGARCHX estimation process. Furthermore, the VS-LTGARCHX algorithm is applied to extremely volatile BTC markets using 42 conditioning variables. Interestingly, our results show that the VS-LTGARCHX models outperform benchmark models, namely the log-GARCH(1,1) and log-TGARCHX(1,1) models, in one-step-ahead forecasting.
High-throughput sequencing reveals twelve cell death pattern prognostic target genes as potential drug-response-associated genes in the treatment of colorectal cancer cells with palmatine hydrochloride
Authors: Luo Sha , Xu Jiajun , Mo Chune , Gong Weiwei , Li Chunhong , Hou Xianliang , Ou Minglin
Published: November 2024

Objectives

Palmatine Hydrochloride (PaH), an isoquinoline alkaloid from Phellodendron amurense and Coptis chinensis, has analgesic, anti-inflammatory, and anticancer properties. This study aimed to assess PaH’s effectiveness against SW480 colorectal cancer (CRC) cells and explore its molecular mechanisms.

Methods

PaH’s effects on SW480 CRC cells were evaluated using MTT assays for proliferation, scratch assays for migration, and flow cytometry for apoptosis. Differentially expressed genes (DEGs) were identified through high-throughput sequencing. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses assessed DEG roles. Prognostic significance related to programmed cell death (PCD) was analyzed using R-Package with TCGA data. RT-qPCR validated key genes identified.

Results

PaH significantly inhibited SW480 cell growth, invasion, and apoptosis. The MTT assay showed inhibition rates increased from 5.49 % at 25 μg/mL to 52.48 % at 400 μg/mL. Scratch assays indicated reduced cell invasion over 24, 48, and 72 h. Apoptosis rose from 12.36 % in controls to 45.54 % at 400 μg/mL. Sequencing identified 3,385 significant DEGs, primarily in cancer pathways (p=0.004). Among 35 PCD-related DEGs, Lasso Cox regression highlighted 12 key genes, including TERT, TGFBR1, WNT4, and TP53. RT-qPCR confirmed TERT and TGFBR1 downregulation (0.614-fold, p=0.008; 0.41-fold, p<0.001) and TP53 and WNT4 upregulation (5.634-fold, p<0.001; 5.124-fold, p=0.002).

Conclusions

PaH inhibits CRC cell proliferation, migration, and invasion by modulating key PCD genes, suggesting its potential as a CRC therapeutic agent.
Combined Nabpaclitaxel pressurized intraPeritoneal aerosol chemotherapy with systemic Nabpaclitaxel-Gemcitabine chemotherapy for pancreatic cancer peritoneal metastases: protocol of single-arm, open-label, phase II trial (Nab-PIPAC trial)
Authors: Di Giorgio Andrea , Ferracci Federica , Bagalà Cinzia , Carbone Carmine , Salvatore Lisa , Strippoli Antonia , Attalla El Halabieh Miriam , Abatini Carlo , Alfieri Sergio , Pacelli Fabio , Tortora Giampaolo
Published: November 2024

Objectives

Current therapies show limited efficacy against peritoneal metastases (PM) from pancreatic cancer. Pressurized intra-peritoneal aerosol chemotherapy (PIPAC) has emerged as a novel intraperitoneal drug delivery method. Recently, a dose-escalation study identified the safe dose of Nabpaclitaxel for PIPAC administration, an ideal intraperitoneal chemotherapy agent against pancreatic cancer. Combining systemic NabPaclitaxel-Gemcitabine with NabPaclitaxel-PIPAC may enhance disease control in pancreatic cancer patients with PM.

Methods

The Nab-PIPAC trial is a single-center, prospective, open-label, phase II study (ClinicalTrials.gov identifier: NCT05371223). Its primary goal is to evaluate the antitumor activity of the combined treatment based on Disease Control Rate (DCR) using RECISTv.1.1 criteria. Secondary objectives include feasibility, safety, pathological response, progression-free and overall survival, nutritional status, quality of life, pharmacokinetics of NabPaclitaxel-PIPAC, and PM molecular evolution via translational research. The treatment protocol consists of three courses, each with two cycles of intravenous NabPaclitaxel-Gemcitabine and one cycle of NabPaclitaxel-PIPAC, with standard metastatic pancreatic cancer doses for the former and 112.5 mg/m2 for the latter. Sample size follows Simon’s two-stage design: 12 patients in stage one and 26 in stage two (80 % power, 0.1 alpha).

Results

Partial results will be available after first stage enrollment.

Conclusions

This trial aims to determine the antitumor efficacy and safety of combining NabPaclitaxel-PIPAC with systemic NabPaclitaxel-Gemcitabine in pancreatic cancer patients with PM.
Forced stability studies and estimation of encapsulated ellagic acid in nano-formulations using UV-spectroscopy
Authors: Kumar Suraj , Khairnar Yogesh , Karmakar Arka , Kumar Lalit
Published: November 2024

There is a growing interest in dietary materials to explore their therapeutic activities. Ellagic acid is considered as a dietary supplement and is naturally present in fruits and other foods. It has anticancer, antimalarial, antiviral, antioxidant, and anti-inflammatory activities. These activities can be enhanced with nanoformulations, which can increase its oral bioavailability. However, there is a need for an economical, simple, sensitive, and robust analytical method for the estimation of entrapped ellagic acid in the nanoformulations. Therefore, the present study presents the development and validation of a UV–visible spectroscopy method for the estimation of EA in nanoformulations. The phosphate buffer (pH 7.2) and the detection wavelength of 253.5 nm were used for the method development, and its validation was performed according to the ICH Q2A (R1) guidelines. The coefficient of determination value of the developed method was found to be 0.9988 in the concentration range of 1 μg mL−1 to 6 μg mL−1. The method was found to be linear, precise, sensitive, and robust. This method can be used for the estimation of EA in nanoformulations, bulk dosage forms, and other pharmaceutical formulations.
Consistent Egalitarianism or Heterogeneous Belief Patterns? Gender Ideologies in Contemporary East and West Germany
Authors: Kleinschrot Leonie
Published: November 2024

Studying gender ideologies is crucial for understanding the work and family related behaviors of women and men. This paper analyzes the gender ideologies of respondents living in East and West Germany, and whether these belief patterns differ by socio-demographic characteristics. To this end, latent class analysis is applied to eight gender role items from the FReDA 2021 survey. The results show the presence of a consistent and widespread egalitarian gender ideology in both regions, as well as a less prevalent traditional one in the West. Additionally, heterogeneous gender ideologies are to be found with egalitarian essentialism present in both regions, and intensive parenting only in the West. Respondents with a lower level of education and males have higher chances of holding non-egalitarian ideologies. The findings align with the literature on persisting East-West differences in gender ideology, and with research on the diversification of gender ideology.
Apresentação
Authors: Souza Inguelore Scheunemann de
Published: November 2024

Certamente a Universidade constitui-se no mais adequado e fértil ambiente para transformar conhecimento acumulado em propostas plenas em criatividade e, estas, em desafios. A energia latente contida em um desafio é capaz de, quando apresentado a pessoas e por pessoas inquietas, aquelas que não se deixam vencer pelas dificuldades e problemas presentes no dia a dia institucional, desencadear uma série de acontecimentos que se traduzem em inovações, novas oportunidades para os estudantes e  interessantes projetos de interesse da sociedade.
CONTANDO ÀS CRIANÇAS SOBRE O PASSADO NO BRASIL
Authors: Piñon Ana , Funari Pedro
Published: November 2024

Resumo: O artigo apresenta, numa perspectiva histórica, o tratamento dopatrimônio brasileiro, utilizando-se, em sua análise, de um estudo de casorelacionado a patrimônio e estudantes no Brasil contemporâneo. Abstract: The paper starts by putting Brazilian heritage management inhistorical context, followed by a case study relating to heritage and pupils in thecontemporary Brazil.
ETNOGRAFIA DOS TERRITÓRIOS JUVENIS NA CIDADE
Authors: Rieth Flávia Maria Silva
Published: November 2024

Resumo:Apresenta-se a etnografia dos espaços de sociabilidade dos jovens nacidade, a qual figura como uma crônica de Pelotas: a Avenida, a Avenida daPraia do Laranjal e o Bar Farol foram os lugares indicados pelos informantes –jovens de 15 a 19 anos de camadas médias. Na Avenida, observa-se o encontrode uma multidão de conhecidos, onde misturam idades e classes sociais,evidenciando as “marcas de pessoalidade” no convite ao olhar o movimento.Distinguem-se os espaços tradicionais daqueles da moda, referências emboracompartilhadas por todos, circunscrevem diferentemente indivíduos e redessociais na cidade. Onde, ganham centralidade os aspectos de geração e gênero,observando-se o pronunciamento do controle sobre os jovens em um contexto de camadas médias do interior. Abstract:The ethnography presents the spaces of intense sociability ofyoung people in the city, which figures as a chronic of Pelotas: the Avenue,Laranjal Beach Avenue and Farol Bar. These places were indicated by theinformers - young people between 15 and 19 years old come from middleclasses. In the Avenue, it notices the meeting with a crowd acquaintances wheremix the ages and the social classes, demonstrating the "personal marks" in theinvitation to take a look at the movement. Traditional spaces distinguish fromfashion spaces. Although everyone shares these references, they constitutedifferently the people and the social network in the city. Therefore, thegeneration and gender aspects become important issues in order to observe thepronounced control of young people in a context of interior middle layers.
É POSSÍVEL FAZER UM MAPA DA CULTURA?
Authors: Neto Edgar , Rieth Flávia
Published: November 2024

No ano de 2001, a recém criada Secretaria Municipal da Cultura dePelotas (SECULT), juntamente com a Universidade Federal de Pelotas (UFPEL), tomaram a iniciativa de criar um projeto para realizar um mapeamento cultural dacidade de Pelotas. Sediado no espaço institucional da SECULT, o projeto tinha como o seu principal objetivo fornecer subsídios (leia-se informação etnográfica etambém, em alguns casos, dados quantitativos) para a formulação de políticasculturais específicas e, mais genericamente, contribuir para os processos de tomadade decisão por parte dos gestores públicos envolvidos com a coordenação daquelaspolíticas.
Involvement of Neurons in the Nonhuman Primate Anterior Striatum in Proactive Inhibition
Authors: Yoshida Atsushi , Hikosaka Okihide
Published: November 2024

Behaving as desired requires selecting the appropriate behavior and inhibiting the selection of inappropriate behavior. This inhibitory function involves multiple processes, such as reactive and proactive inhibition, instead of a single process. In this study, two male macaque monkeys were required to perform a task in which they had to sequentially select (accept) or refuse (reject) a choice. Neural activity was recorded from the anterior striatum, which is considered to be involved in behavioral inhibition, focusing on the distinction between proactive and reactive inhibitions. We identified neurons with significant activity changes during the rejection of bad objects. Cluster analysis revealed three distinct groups, of which only one showed increased activity during object rejection, suggesting its involvement in proactive inhibition. This activity pattern was consistent irrespective of the rejection method, indicating a role beyond saccadic suppression. Furthermore, minimal activity changes during the fixation task indicated that these neurons were not primarily involved in reactive inhibition. In conclusion, these findings suggest that the anterior striatum plays a crucial role in cognitive control and orchestrates goal-directed behavior through proactive inhibition, which may be critical in understanding the mechanisms of behavioral inhibition dysfunction that occur in patients with basal ganglia disease.
Regulations of the Grand Duke of Lithuania for the landowners of Vilnius and Trakai in 1529
Authors: Truskauskaitė Neringa
Published: November 2024

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The Conference "The 1941's in Lithuania: the beginning of the war and the June's uprising"
Authors: Zizas Rimantas
Published: November 2024

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J. K. Valiunas. Serving Lithuania. - (N. Y., 1982) - 288 p. History through autobiography
Authors: Jakubčionis Algirdas
Published: November 2024

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A caricaturistic portrait of Ovid from Brigetio (Komárom/Szőny, Hungary)
Authors: Bartus Dávid , Borhy László
Published: November 2024

In 2015 a preventive excavation was carried out preceding the laying of an optical cable in close vicinity to the legionary fortress of Brigetio. An otherwise regular Roman terracotta roof tile was found during the excavation, with the image of a bearded man and the inscribed name of Ovidius Naso. The depiction of the poet leans more towards caricature rather than a realistic portrait, but since we do not know of any ancient representations of Ovid, it is of great importance and fits well into the series of other graffiti on roof tiles from Pannonia.
Versatility of Raman spectroscopy for studies on the back-end of the nuclear fuel cycle
Authors: Elorrieta J. M. , Bonales L. J. , Milena-Pérez A. , Sánchez-García I. , Rodríguez-Villagra N. , Galán H.
Published: November 2024

In recent years, Raman spectroscopy has been proven to be a highly versatile characterization technique for nuclear materials research. This sensitive technique possesses, among others, two relevant features that comply with the safety conditions required when handling nuclear materials: its flexibility allows for remote, in situ and ex situ analysis, and its relative ease of use implies small sample quantities and limited effort for sample preparation. In this work, we present the acquisition protocol and data processing necessary for obtaining important information within the back-end of the nuclear fuel cycle. Specifically, we focus on research studies on the advanced characterization of nuclear fuels and the development of hydrometallurgical separation processes. The results described here were obtained by using different nuclear fuels analogs, but the acquisition protocol and data processing described can be applied to the real nuclear fuel cycle.

Graphical abstract
Ontology modeling for automation of questionnaire data processing
Authors: Iklassova Kainizhamal , Aitymova Aliya , Kopnova Oxana , Shaporeva Anna , Abildinova Gulmira , Nurbekova Zhanat , Almagambetova Leila , Gorokhov Alexey , Aitymov Zhanat
Published: November 2024

The object of this study is the analysis of questionnaire data using ontological modeling. The task relates to the fact that conventional methods for processing questionnaire data are often insufficiently effective when working with large volumes of information and do not make it possible to automate many analysis processes.
As a result of the study, an ontology was designed that structures and analyzes questionnaire data, which allows for a more accurate identification of hidden relationships between variables. Using these theoretical provisions, an information system for assessing the quality of assimilation of preschool children's competencies was built. 150 children from various preschool organizations were involved in the study as respondents. The data integration method proposed in this paper significantly facilitated the process of data analysis both for a group and for an individual respondent.
The key difference of the proposed methodology is the automation of routine data analysis operations based on the ontological structure, which significantly simplifies the processing of large volumes of information. This makes it possible to solve the problem of limitations in conventional analysis methods and makes data analysis more scalable and reproducible.
The practical application of the results is possible in marketing for analyzing customer satisfaction, market segmentation, and evaluating the effectiveness of advertising campaigns. In the educational domain, the ontology could be used to evaluate the quality of programs and analyze respondents' opinions, and in sociology – to analyze public opinion and conduct research on social phenomena.
Thus, the proposed ontology provides an effective tool for analyzing large volumes of questionnaire data, allowing organizations to make more informed decisions and improve their efficiency
Genetic diversity of Eugenia stipitate based on the physical and physicochemical characteristics of the fruits in tropical conditions
Authors: Chagas Pollyana Cardoso , Chagas Edvan Alves , Moura Elias Ariel , Santos Ricardo Carvalho dos , Oliveira Railin Rodrigues , Nascimento Vanessa Barbosa , Cruz Beatriz Emanuela Pereira da , Nascimento Fabiana Barbosa do
Published: November 2024

Abstract: The objective of this study was to evaluate the genetic diversity between genotypes based on the physical, chemical and physicochemical characteristics of araçá-boi in tropical conditions. The experiment was carried out at the Federal University of Roraima, in the municipality of Boa Vista, Roraima, Brazil. Genotypes were obtained in the F1 generation, through open pollination. Twelve plants were evaluated, with 10 fruits being collected per plant. The physical and physicalchemical characteristics of the fruits were evaluated: fresh mass, length and diameter of the fruits, pulp yield, firmness, mass of the pulp, peel and seeds, number of seeds, soluble solids, tritratable acidity, pH, ratio SS/AT and vitamin C from fruits. The araçá-boi genotypes showed medium to high genetic variability, obtaining averages for the physical and physicalchemical characteristics higher than those observed in the literature. G genotypes A9, A10 and A6 adopted fruits with larger sizes and produced a greater number of fruits genotypes A1 obtained fruits with higher organoleptic quality. Genotypes A3 produced fruits with higher levels of Vitamin C and fruits with greater firmness. Genotypes A3, A6, A9 and A10 were promising with high agronomic potential and could be selected for the genetic improvement program of the species.
Formation pruning intensities and container volumes in the production of advanced sour passion fruit seedlings
Authors: Fabro Fabio Feltrin , Petry Henrique Belmonte , Marchesi Darlan Rodrigo , Schwarz Sergio Francisco , Schneider Leonardo André
Published: November 2024

Abstract: The objective of this work was to evaluate the production of advanced seedlings of sour passion fruit (Passiflora edulis Sims.) in pruning intensities at different volumes of containers. The experiment was carried out in a production nursery, in Pedras Grandes, Santa Catarina state. The experimental design was a randomized block design and the treatments were arranged in a factorial scheme of five pruning intensities (control and pruning from the emission of 2, 4, 6, and 8 defined leaves) x 3 container volumes (1.0; 1.7 and 3.6 liters), with three replications and six plants per plot. The height and number of leaves (NF) of the seedlings were evaluated throughout the experiment and, at the end, the percentage of plants with a twisted root system (PSRE), root volume (VR), root dry mass (MSR), aerial part (MSPA) and total were measured (MST). The control treatment (without pruning) showed greater height, NF, MSPA and MST, regardless of container volume. The production of advanced sour passion fruit seedlings under pruning intensities reduced height, NF, MSPA and MST. Seedlings formed in larger volume containers provided greater height, NF, VR, MSR, MSPA and MST, in addition to the lowest PSRE. Therefore, pruning at an intensity of 6 leaves in a 1.7 liter container is recommended.
Genetic variability and population structure in guava full-sib families via microsatellite markers
Authors: Walter Fernando Henrique de Barros , Cavalcante Natan Ramos , Viana Alexandre Pio , Santos Eileen Azevedo , Mendes Débora Souza , Oliveira Julie Anne Vieira Salgado de , Ramos Helaine Christine Cancela , Boechat Marcela Santana Bastos
Published: November 2024

Abstract: Guava production is a promising activity with great prominence in several regions of Brazil; however, a major obstacle faced by producers is the low number of available cultivars. The present study proposes to estimate and analyze genetic structure and variability, through molecular traits, aiming at the future development of new cultivars. Ninety-four genotypes from 11 full-sib families and the cultivars Paluma, Pedro Sato, and Cortibel 1 were selected for DNA extraction, totaling 97 genotypes. For molecular characterization, 48 pairs of microsatellite primers were used. This information was used to estimate the parameters of genetic diversity, genetic distance, genotype clustering, and the genetic structure of the population. The use of molecular information revealed the existence of genetic variability between the genotypes of the full-sib families and the cultivars. The average number of alleles per locus was 2,542. Expected heterozygosity values ranged from 0.030 to 0.599, averaging 0.401. Observed heterozygosity ranged from 0.010 to 0.577, averaging 0.293. Based on the UPGMA hierarchical clustering method, four groups were formed and crossing is recommended between individuals from groups 1 and 2. Bayesian analysis allowed the distinction of genotypes into only two groups, due to the individuals sharing most of the genomic regions analyzed.
Letícia AF: New self-compatible plum cultivar resulting of a mutation of Laetitia
Authors: Dalbó Marco Antônio , Argenta Luiz Carlos
Published: November 2024

Abstract: Letícia AF is a mutation of the plum cultivar Laetitia that confers self-compatibility. This work compared the Letícia AF mutant cultivar with the standard Laetitia regarding fruit set, self-compatibility, yield, and fruit quality traits during four growing seasons. The study was carried out in two plum orchards with the cultivar Letícia AF (orchard 1) and Laetitia plus pollinizers trees (orchard 2) and in an experimental unit with Letícia AF and Laetitia planted side by side. A self-compatibility test was performed on covered branches to prevent pollinating insects from reaching the flowers. Fruit set occurs in covered branches of Letícia AF, whereas it was rare in Laetitia. In commercial orchards, Leticia AF plums yield was higher than that of Laetitia over the years. The results suggest that the oscillation in productivity across the years, mainly due to unfavorable conditions for insect pollination, may be lower in the plum Leticia AF orchard. On the other hand, the requirement for fruit thinning may be greater in Leticia AF. No significant differences were found between the mutant and the standard cultivar regarding fruit quality at harvest and after 30 days of cold storage, indicating the mutation did not alter the fruit characteristics.
Nutrient export by cupuassu fruits grown in the Brazilian Amazon
Authors: Vieira Marlene Evangelista , Freitas Marta Simone Mendonça , Viégas Ismael de Jesus Matos , Alves Rafael Moysés , Cunha Jéssica Morais , Peçanha Diego Alves , Jesus Assistone Costa de , Carvalho Almy Junior Cordeiro de
Published: November 2024

Abstract: In Theobroma grandiflorum (cupuassu) orchards, efficient nutrient management is essential to achieve high yields and fruit quality. Thus, fertilization programs should be guided by the concentration of nutrients exported by fruits, as observed with other fruit species. The aim of this study was to quantify the export of macro and micronutrients by fruits of cupuassu genotypes, in order to guide nutrient replacement recommendations replacement. Six cupuassu genotypes (‘BRS Careca’, ‘BRS Fartura’, ‘BRS Duquesa’, ‘BRS Curinga’, ‘BRS Golias’ and ‘genotype 63’) were used, and 40 fruits per genotype were sampled, totaling 240 fruits, in the municipality of Tomé-Açu (Pará/Brazil). Fruits were broken and manually pulped and then separated into peel, seed and pulp. In each fruit part, the contents of macro and micronutrients were analyzed, and later extrapolated to ton of fresh fruits. Potassium was the macronutrient most exported by cupuassu fruits, and ‘genotype 63’ accounted for the largest exports per ton of fresh fruits of this nutrient. The export of nutrients per ton of fresh fruits followed this order for macronutrients (kg ton-1): K (4.34), N (2.73), P (0.54), Mg (0.40), S (0.29), Ca (0.26) and for micronutrients (g ton-1): Zn (6.24), Fe (4.97), Mn (3.49), Cu (2.45), Ni (0.18) and Mo (0.11). The average replacement per plant and per year, during the productive phase, for the five Cupuassu genotypes is 471 g of K2O, 326 g of N, 245 g of P2O5, 27 g of CaO, 56 g of MgO, 63 g of SO4-2 and 15 g of Fritted Trace Elements (FTE).
Estudo descritivo dos eventos supostamente atribuíveis à vacinação contra a mpox no Brasil em 2023
Authors: Silva Roberta Mendes Abreu , Kobayashi Carla Dinamerica , Martins Adriano Ferreira , Araújo Ana Catarina de Melo , Andrade Paulo Henrique Santos , Nóbrega Martha Elizabeth Brasil da , Cabral Cibelle Mendes , Moraes Monica Brauner de , Cardoso Felipe Daniel , Victer Thayssa Neiva da Fonseca , Krummenauer Amanda , Soares Rodrigo Otávio Pereira Sayago , Fernandes Eder Gatti , Percio Jadher
Published: November 2024

Resumo: O objetivo deste estudo é descrever as ações de vigilância e segurança da vacina contra a mpox (Jynneos) no Brasil, de 2022 a 2023. Realizou-se estudo descritivo dos casos de mpox e dos eventos supostamente atribuíveis à vacinação e/ou imunização para vacina Jynneos, registrados nos sistemas de informação. Foram calculadas frequências absolutas e relativas e coeficientes de notificação de eventos supostamente atribuíveis à vacinação e/ou imunização por mil doses administradas. Foram registrados 9.596 casos de mpox e distribuídas 49 mil doses de vacina; dessas, 14.395 (31%) doses foram administradas e 65 eventos supostamente atribuíveis à vacinação e/ou imunização (4,5 por mil doses administradas) foram notificados. Todos os eventos supostamente atribuíveis à vacinação e/ou imunização foram não graves e 22 (33,8%) casos apresentaram reações relacionadas ao produto. Os resultados estão dentro da frequência esperada. No entanto, o número de doses administradas pode não ter sido suficiente para detectar eventos raros ou inusitados. Portanto, a vigilância contínua é necessária para garantir a efetividade e a segurança da vacinação, especialmente entre os grupos de maior risco.
Impacto do serviço de telediagnóstico nas internações por doenças cardiovasculares: uma abordagem em municípios da Bahia, Brasil
Authors: Piropo Thiago Gonçalves do Nascimento , Ramos Francisco de Sousa
Published: November 2024

Resumo: Os gastos com internações por doenças do aparelho circulatório são elevados: em 2019, apenas para o Estado da Bahia, Brasil, excederam 153 milhões de reais para o Sistema Único de Saúde, superando os custos de internações por câncer. Esse fato tende a se acentuar com o aumento da expectativa de vida no Brasil (7,3 anos a mais até 2060). A introdução de novas tecnologias pode mitigar o problema. Este estudo analisa o impacto da utilização do telediagnóstico em eletrocardiograma nas internações por doenças cardiovasculares, em 326 municípios baianos durante o período de 2014 a 2020. O método de estimador diff-in-diff foi utilizado para a análise entre os períodos anterior e posterior à implantação do serviço no estado. Os resultados mostram que os municípios que introduziram a nova tecnologia reduziram em seis internações por doenças cardiovasculares a cada ano adicional. No caso das famílias beneficiadas pelo Bolsa Família, a redução foi de 3,26 internações, e de 3,08 entre os municípios com o serviço especializado. Verificou-se um aumento de 7,66 internações na faixa etária de 30 a 59 anos e um aumento de 5,34 entre homens, a cada ano adicional. Os resultados evidenciam uma redução de 1,15 internações por doenças cardíacas reumatológicas e de 1,39 entre as pessoas diabéticas. No quesito raça/cor, foi identificada subnotificação nas condições estudadas, resultando em prognósticos mais severos para a população preta. A tecnologia mostrou-se eficaz para reduzir essa desigualdade, ao expandir o acesso e reduzir as internações, tendo um papel crucial na saúde coletiva e impactando na redução da mortalidade. O tema, portanto, é merecedor de mais estudos, com amostras e períodos amostrais diferentes.
Abortion due to Yersinia enterocolitica infection in an ewe in Southern Brazil
Authors: Paz Milena Carolina , Lamego Eryca Ceolin , Santos Igor Ribeiro dos , Henker Luan Cleber , Lorenzett Marina , Lopes Bruna Correa , Driemeier David , Pavarini Saulo Petinatti
Published: November 2024

ABSTRACT: We described the pathological findings of an abortion associated with Yersinia enterocolitica infection in an ewe. A late-gestation aborted ovine fetus and placenta were submitted for necropsy. Pathologic changes were restricted to the chorioallantois. Grossly, cotyledons and intercodilenary regions had areas of mild red discoloration, and cotyledons were covered with a small amount of fibrin. Histological lesions consisted of multifocal, severe necrotizing and fibrinosuppurative placentitis with fibrinoid vasculitis and mineralization. Bacterial culture of lung, abomasum, and placenta samples yielded pure growth of Y. enterocolitica. This report described the first case of infection by Yersinia enterocolitica causing ovine abortion in Brazil.
Milk microbiota of clinical mastitic cows: an etiological approach
Authors: Lucheis Simone Baldini , Salina Anelise , Joaquim Sâmea Fernandes , Guerra Simony Trevizan , Guimarães Felipe Freitas , Ribeiro Márcio Garcia , Rall Vera Lúcia Mores , Hernandes Rodrigo Tavanelli , Leite Domingos da Silva , Curci Vera Cláudia Magalhães , Rossi Gabriel Augusto Marques , Langoni Helio
Published: November 2024

ABSTRACT: Bovine mastitis is the most impacting disease of dairy industry, and it is characterized by a complexity of causal agents, which have revealed a geographical variation among regions and countries. The mastitis-related pathogens have been traditionally classified as contagious or environmental, based on habits of the microorganisms and transmission routes. Besides, the severity of mammary infections has been associated with the virulence of the pathogens, and immune and nutritional status of the hosts. Considering this scenario, we investigated the etiological pattern, clinical severity scores, and days in milk (DIM) data in 4,273 clinical cases of bovine mastitis among ten large-dairy farms located in Brazil. Streptococcus dysgalactiae (283/4,273 = 6.6%), Escherichia coli (190/4,273 = 4.4%), Prototheca spp. (112/4,273 = 2.6%), and Streptococcus uberis (95/4,273 = 2.2%) were the predominant pathogens isolated. Among 4,273 clinical cases, clinical severity score was available in 43.8% (1,871/4,273) animals. From these, 69.8% (1,306/1,871), 27.3% (510/1,871), and 2.9% (55/1,871) were scored as mild, moderate, and severe, respectively. Pathogens were observed mainly in samples obtained during the first 100 days in milk, and clinical severity scored mainly as mild. Our results contributed to the etiological identification, clinical severity scoring, and milking aspects of mastitic cows in dairy farms with a history of clinical mammary infections.
Ultrasound applied at low temperature on the extraction and modification of proteins from by-products of the fishing industry
Authors: Robalo Silvino Sasso , Cargnin Gregorio , Silva Leila Picolli da , Campagnol Paulo Cezar Bastianello , Wagner Roger , Barin Juliano Smanioto , Brasil Carla Cristina Bauermann , Menezes Cristiano Ragagnin de , Cichoski Alexandre José
Published: November 2024

ABSTRACT: This study explored the use only of ultrasound (US) for extracting proteins from grass carp (Ctenopharyngodon idella) backbones at low temperature and examined its impact on hydrophobicity, solubility, electrophoretic profile, and sulfhydryl levels. Backbones were treated with 35 and 130 kHz for 20, 30, and 40 minutes at 14 ºC, resulting in two protein fractions: solid (TPS) and liquid (TPL). US increased yield compared to the non-sonicated fraction. TPL (35 kHz) exhibited a 16% reduction in total and free sulfhydryl levels and a 25% increase in hydrophobicity. US induced protein conformation and band intensity alterations, particularly between 25 to 100 kDa for TPL at 130 kHz and below 30 kDa for TPS at 35 kHz. This study demonstrated the efficacy of US for protein extraction from fish by-products and its capacity to modify protein characteristics, facilitating the development of innovative food products.
Satisfação dos usuários atendidos na Atenção Básica em Saúde e a oferta de Práticas Integrativas e Complementares em Saúde
Authors: Bretz Yasmin Pissolati Mattos , de Paula Janice Simpson , Gonçalo-Mialhe Camila , Mialhe Fábio Luiz
Published: November 2024

Resumo Introdução: Práticas Integrativas e Complementares em Saúde ampliam o cuidado em saúde. Objetivo: avaliar a satisfação dos usuários atendidos na Atenção Básica e a oferta de Práticas Integrativas e Complementares em Saúde no Sistema Único de Saúde. Método: Foram utilizadas questões do 3° ciclo do Programa de Melhoria do Acesso e da Qualidade da Atenção Básica do qual participaram 140.121 usuários de 36.808 equipes de saúde. A variável desfecho foi mensurada por meio da questão "Na sua opinião, o cuidado que o(a) senhor(a) recebe da equipe de saúde é:". Resultados: Apresentaram menor chance de satisfação os usuários que moravam mais distantes das Unidades de Saúde; cujo horário de funcionamento não atendia suas necessidades ou atendiam às vezes; com os profissionais que quase nunca/nunca perguntavam sobre outras questões da sua vida; que se sentiam algumas vezes ou não se sentiam respeitados pelos profissionais; que acreditavam que a forma como foram acolhidos foi regular, ruim ou muito ruim; em locais cujas equipes não participaram de ações de educação permanente e que não ofereciam Práticas Integrativas e Complementares em Saúde. Conclusão: o oferecimento de Práticas Integrativas e Complementares em Saúde foi um fator que contribuiu favoravelmente para a satisfação dos usuários atendidos na atenção básica.
Growth of soybean plants cultivated in soil and fertilized with silicon
Authors: Oliveira C. F. , Costa K. S. Q. , Melo M. P. , Lima H. C. , Cordovil H. P. L. , Moreira A. V. P. , Melo N. C. , Moraes F. K. C. , Ferreira R. L. C. , Cruz F. J. R. , Feitosa E. O. , Souza L. C. , Nascimento V. R.
Published: November 2024

Abstract Although silicon is not considered an essential element, in some crops such as soybeans, its supply can stimulate plant development and plant production. The growth of soybean cultivars in Cerrado soil subjected to the application of silicon doses was studied. The experiment was conducted in a greenhouse at the Instituto Federal do Amapá – IFAP/Campus Agrícola Porto Grande. The experimental design was completely randomized, arranged in a 5x2 factorial scheme, with four replications. The factors consisted of the control treatment (without Si) and four doses of Si (250, 500, 750 and 1000 mg pot-1 of SiO2), and two soybean cultivars (BRS Tracajá and FTS Paragominas). Growth variables were analyzed, such as: plant height, stem diameter; and dry matter of shoots and roots. Silicon influenced the increase in height when evaluating the cultivars and isolated doses, the same behavior was observed in the dry matter production of the aerial part and total. The element silicon helps in the improvement and gain in height and other evaluated agronomic characteristics, but studies with this element must be more applied, to obtain the answer for other variables and study conditions.
Compressive lesions of the central nervous system in goats and sheep: A retrospective study of 11 cases in the Amazon biome
Authors: Barbosa Camila C. , Lopes Cinthia T.A. , Ferreira Tatiane T.A. , Oliveira Carlos M.C. , Campos Karinny F. , Bomjardim Henrique A. , Brito Marilene F. , Barbosa José D.
Published: November 2024

ABSTRACT: This paper describes, within the framework of a retrospective study, the epidemiological and clinicopathological findings in goats and sheep with compressive lesions of the central nervous system (CNS) in Pará. This study included eight sheep and three goats from 2005 to 2022 by reviewing the clinical files of animals with CNS compressive lesions managed by the team of the Carlos Tokarnia Veterinary Hospital of the Institute of Veterinary Medicine of the Federal University of Pará. The animals with clinical signs were subjected to a general and specific clinical examination of the nervous system. All animals included in the study were necropsied, and the clinical signs were found to vary according to the location of the lesion. At necropsy, changes such as an abscess with osteomyelitis of the vertebral body with pathologic fracture and spinal cord compression, submeningeal abscess in the skull floor, subarachnoid hematoma, and congenital bone changes causing spinal cord compression and ankylosing spondylitis were noted. These findings indicate that a comprehensive clinical examination of the CNS in conjunction with necropsy findings is essential to characterize the clinical picture, localize the lesion, and determine the cause of the disease. The most affected medullary segment was between T3 and L3. Therefore, these diseases should be included in the list of differential diagnoses in farm animals with nervous system symptoms.
Por uma Extensão Universitária Latino-Americana e Feminista
Authors: Ketzer Patricia , Ribeiro Silvana , Pereira Thiago Ingrassia
Published: November 2024

Resumo: No presente artigo, visamos analisar a extensão universitária partindo da exclusão das mulheres da produção, transmissão e disseminação do conhecimento. Compreendemos a extensão universitária como dimensão fundamental do fazer acadêmico, responsável pela produção e compartilhamento de conhecimentos com a comunidade. A extensão, articulada com o ensino e a pesquisa, assume um caráter indispensável na formação integral das/os estudantes e na formação das/os professoras/es e da comunidade em geral. Nesse sentido, faz-se necessário problematizar o lugar da mulher nas práticas extensionistas. No decorrer do artigo, nos propomos a pensar a emergência e o fortalecimento de uma epistemologia feminista no cerne da extensão.
Filosofia (feminista) da ciência: a contribuição de Nancy Tuana
Authors: Reis Júnior Dante Flávio da Costa
Published: November 2024

Resumo: Nos últimos quarenta anos, amplificou-se o campo dos estudos filosóficos e históricos sobre a ciência. Parte dessa evolução tem a ver com o desenvolvimento de epistemologias críticas; por exemplo, a análise das práticas científicas pelo olhar feminista. Ressaltamos, neste artigo, a produção intelectual de uma importante autora, Nancy Tuana. O propósito é o de demonstrar à comunidade de estudiosas do feminismo o estado atual do debate sobre ciência e gênero, realçando o mérito de uma bibliografia que revitalizou as primeiras discussões feministas em epistemologia. Baseado em algumas das publicações mais emblemáticas da personagem, o texto faz uma apresentação panorâmica de seus pensamentos. E conclui que as reflexões da autora (que mesclam perspectivas analíticas herdadas e renovadas) mantêm intacto o valor da crítica feminista para a ciência contemporânea.