bluuebunny/crossref_metadata_2025 huggingface dataset:
Effectiveness of virtual reality glasses with integrated sign language in reducing dental anxiety during pulpotomy in children with hearing impairment: a randomized controlled trial
Authors: Salama Reem Moustafa , El-Habashy Laila Moustafa , Zeitoun Sarah Ibrahim
Published: November 2024

Background

Children with hearing impairment (HI) face communication challenges during dental procedures due to hearing loss. Studies suggest that distraction techniques, like virtual reality (VR), can effectively divert their focus from stressful stimuli, resulting in a more comfortable dental experience. The present study aims to assess the effectiveness of distracting children with moderate to severe (HI) with virtual reality glasses that show cartoons in sign language during pulpotomy treatment compared to conventional management techniques.

Methods

Forty children aged five to seven participated in a randomized controlled parallel two-arm clinical trial—the type of behavioral management employed determined which two groups children were randomly placed into. Group I (Study group) used virtual reality glasses as a diversion, while Group II (Control group) used the conventional behavior management approach. Local anesthesia was administrated, and a pulpotomy procedure was performed on the selected tooth, followed by stainless steel crown restoration (SSC). There were three methods used to assess dental anxiety before and after the procedure: the physiological method, which used heart rate (HR); the objective measure, which used the Venham Clinical Anxiety Scale (VCAS); and the subjective measure, which used the modified Facial Affective Scale (FAS). An independent t-test was employed for HR analysis of the difference between the groups as a continuous variable. The Pearson Chi-square test assessed differences between groups for categorical variables, such as (VCAS) (FAS).

Results

No significant differences were found in mean (HR) or (VCAS) between the two groups throughout the procedures: during local anesthesia (p = 0.659, 0.282), pulpotomy (p = 0.482, 0.451), and stainless steel crown preparation (p = 0.090, 0.284). Anxiety levels by (FAS) remained statistically comparable between the two groups before and after the procedures (p = 0.507, 0.749), respectively.

Conclusions

The use of VR glasses revealed no significant advantages in managing children with HI during the dental visit compared to the conventional method of child behavior management.

Trial registration

The trial was prospectively enrolled on 11/11/2023 under the identification number NCT06153823 on ClinicalTrials.gov.
Epidemiology of cleft lip and palate in Bhutan, 2015–2022
Authors: Tobgyel Karma , Rai Prakriti , Choden Kuenga , Gyeltshen Tshewang
Published: November 2024

Background

The epidemiology of cleft lip (CL) and cleft palate (CLP) has not previously been described in the context of the Bhutan and Bhutanese populations. Using National Birth Defects Surveillance Data and other vital statistics, we present the comprehensive epidemiology of the cleft lip and palate in Bhutan.

Methodology

The National Birth Defects Surveillance Data Registry from 2015 to 2022 is reviewed retrospectively, covering 8 years of birth defect surveillance in the country from records maintained with three referral hospitals in the country. The baseline prevalence and incidence of cleft lip and palate have been presented over the years. The incidence of cleft lip and palate was defined as the number of cases per 1000 live births. We used Poisson’s regression to compute the incidence of cleft lip and palate. Pearson chi-square tests (χ2) were used to examine the associations of maternal and child characteristics with cleft lip and palate.

Results

A total of 1401 newborns with various birth defects were born among the 89,078 live births from 2015 to 2022 in Bhutan. Of these, 122 (8.7%) constituted orofacial clefts. The prevalence of orofacial clefts tended to increase, with a period prevalence of 1.37 per 1000 live births. There were more cases in males (72) than in females (50). The incidence rate ratio ranged from 1.2 to 2.0 compared with the 2015 baseline year, indicating increased rates over time.

Conclusion

Orofacial clefts constituted 8.7% of total birth defects and 1.37 per 1000 live births over the years. The increasing prevalence trends and incidence rate ratios over the years underscore the importance of ongoing surveillance and interventions to address the burden of orofacial clefts in Bhutan.

Clinical trial number

Not applicable.
Accuracy of full-guided versus half-guided implant procedures carried out with digital implant planning software by students as part of a university curriculum
Authors: Einsiedel Daniel , Giacaman Stephanie Knapp , Seidel Anna , Berger Lara , Buchbender Mayte , Wichmann Manfred , Matta Ragai Edward
Published: November 2024

Background

This in vitro study investigated whether full-guided (FG) or half-guided (HG) implant placement is more suitable for beginners and to what extent the use of the coDiagnostiX (CDX) (10.5, Straumann Group, Basel, Switzerland) implant planning software proves useful in teaching.

Methods

Twenty students planned implant positions with CDX which were then placed in a model using printed drill templates in the sense of FG implantation (group 1) and HG implantation (group 2). The implant positions could be compared with those of the reference model, and deviations could be determined. The results were tested for significance using the t-test for independent samples for groups 1 and 2. A total of 32 students subsequently completed a questionnaire about the software. Cronbach's α was also calculated to check the reliability of the questions for the individual subject areas.

Results

In both groups the greatest deviation occurred along the y-axis in the vestibular direction. It measured 1.390 mm in group 1 and 1.570 mm in group 2. Comparing both groups, there were significant deviations along the y-axis (p = .013), along the z-axis (p = .049), and in the total deviation (p = .031). The questionnaire was evaluated in design, with 95% positive answers. In contrast, the evaluation of the area of time and effort resulted in only 55% positive responses. Overall, experience with the software was rated as positive by 74%.

Conclusions

Group 1 achieved more accurate results, especially along the y-axis in the vestibular direction. In both groups, the implants were placed too deep. The questionnaire indicated a software with high usability and is therefore very suitable for teaching. If clinically feasible, beginners should prefer full-guided implant placement.
Hearing impairment and vestibular function in patients with a pathogenic splice variant in the LHX3 gene
Authors: Kjellgren Åsa , Lundgren Elenor , Golovleva Irina , Kriström Berit , Werner Mimmi
Published: November 2024

Background

LHX3 is a gene encoding a LIM-homeodomain transcription factor important for the fetal development of several organs, such as the pituitary gland, spinal motor neurons and the inner ear. Pathogenic and likely pathogenic variants in the LHX3 gene are infrequent and result in a rare syndrome known as combined pituitary hormone deficiency-3, CPHD3.

Methods

We have studied hearing and vestibular functions in a group of eight individuals, aged 8–36 years, all of whom were homozygous for a specific variant in the LHX3 gene at chromosome 9q34. We reexamined the results of consecutive hearing tests from newborn until April 2024.

Results

Our data showed that all the tested patients had progressive sensorineural hearing deficiency ranging from moderately severe to complete loss. We have performed vestibular testing in six patients and, for the first time, demonstrated that a mutation in the LHX3 gene not only affects hearing, but is also associated with vestibular impairment.

Conclusion

The human pathogenic variant c.455-2A > G in the LHX3 gene on chromosome 9q34, which present as a founder mutation in the population in northern Sweden, is responsible for phenotypes associated with progressive hearing loss and balance impairment. These findings prove that the LHX3 gene is crucial for the function of both the cochlear and vestibular organs.
Updated evidence on cardiovascular and renal effects of GLP-1 receptor agonists and combination therapy with SGLT2 inhibitors and finerenone: a narrative review and perspectives
Authors: Sawami Kosuke , Tanaka Atsushi , Node Koichi
Published: November 2024

Glucagon-like peptide-1 receptor agonists (GLP-1RAs) have a reliable hypoglycaemic and weight-loss effect that can intervene in obesity, which is the basis of type 2 diabetes pathology. GLP-1RA therapy has shown potential benefits in reducing the risk of major adverse cardiovascular events and improving kidney outcomes in patients with diabetes at high risk for cardiovascular disease. More recent evidence is expanding their benefits to heart failure with preserved ejection fraction and clinically important renal outcomes in patients with and without diabetes. Some sub-analyses of large clinical trials suggest that GLP-1RA and sodium-glucose cotransporter 2 inhibitor combination therapy may provide more significant reductions in heart failure hospitalization and renal composite events than each alone. Moreover, the addition of finerenone to this combination therapy could potentially provide stronger cardiorenal protective benefits. Further studies are needed to assess the potential cardiovascular and renal benefits of combination therapy and to determine suitable patient population for the therapy.

Graphical abstract

Suspected clinical impacts of GLP-1RAs, SGLT2is, and finerenone oncardiovascular and kidney outcomes. CV, cardiovascular; GLP-1RA, glucagon-like peptide-1 receptor agonist; HFpEF, heart failure with preserved ejection fraction; HFrEF, heart failure with reduced ejection fraction; MI, myocardial infarction; SGLT2i, sodium-glucose cotransporter 2 inhibitor.
MDM2 drives resistance to Osimertinib by contextually disrupting FBW7-mediated destruction of MCL-1 protein in EGFR mutant NSCLC
Authors: Liu Jiaxin , Wei Lingyun , Miao Qing , Zhan Sutong , Chen Peilin , Liu Wei , Cao Liang , Wang Dong , Liu Hongbing , Yin Jie , Song Yong , Ye Mingxiang , Lv Tangfeng
Published: November 2024

Background

Overcoming resistance to Osimertinib in epidermal growth factor receptor (EGFR) mutant non-small cell lung cancer (NSCLC) is clinically challenging because the underlying mechanisms are not fully understood. The murine double minute 2 (MDM2) has been extensively described as a tumor promotor in various malignancies, mainly through a negative regulatory machinery on the p53 tumor suppressor. However, the significance of MDM2 on the sensitivity to Osimertinib has not been described.

Methods

Osimertinib resistant cells were generated by standard dose escalation strategy and individual resistant clones were isolated for MDM2 testing. The MDM2 and its mutant constructs (ΔPBD, ΔRING, C464A) were introduced into PC-9, HCC827 and H1975 cells and evaluated for the sensitivity to Osimertinib by MTT assay, colony formation, EdU assay and TUNEL assay. MDM2 expression in resistant cells was manipulated by pharmacological and molecular approaches, respectively. Proteins that were implicated in PI3K/Akt, MAPK/Erk and apoptosis signaling were measured by Western blot analysis. Candidate proteins that interacted with MDM2 were captured by immunoprecipitation and probed with indicated antibodies.

Results

In comparison with parental PC-9 cells, the PC-9 OR resistant cells expressed high level of MDM2. Ectopic expression of MDM2 in PC-9, HCC827 and H1975 sensitive cells generated an Osimertinib resistant phenotype, regardless of p53 status. MDM2 promoted resistance to Osimertinib through a PI3K/Akt and MAPK/Erk-independent machinery, in contrast, MDM2 selectively stabilized MCL-1 protein to arrest Osimertinib-induced cancer cell apoptosis. Mechanistically, MDM2 acted as a E3 ligase to ubiquitinate FBW7, a well-established E3 ligase for MCL-1, at Lys412 residue, which resulted in FBW7 destruction and MCL-1 stabilization. Targeting MDM2 to augment MCL-1 protein breakdown overcame resistance to Osimertinib in vitro and in vivo. Finally, the clinical relevance of MDM2-FBW7-MCL-1 regulatory axis was validated in mouse xenograft tumor model and in NSCLC specimen.

Conclusion

Overexpression of MDM2 is a novel resistant mechanism to Osimertinib in EGFR mutant NSCLC. MDM2 utilizes its E3 ligase activity to provoke FBW7 destruction and sequentially leads to MCL-1 stabilization. Cancer cells with aberrant MDM2 state are refractory to apoptosis induction and elicit a resistant phenotype to Osimertinib. Therefore, targeting MDM2 would be a feasible approach to overcome resistance to Osimertinib in EGFR mutant NSCLC.
Evaluation of a multi-component prevention concept for hazardous substance use among refugees in shared accommodations: study protocol for a cluster randomized controlled trial
Authors: Lorenz Miriam Hedwig , Uricher Jonathan , Pauzar Markus Iwan , Michalak Johannes , Laging Marion , Heidenreich Thomas
Published: November 2024

Background

Refugees are exposed to various risk factors in shared accommodations in Germany where they are housed after their arrival. Due to their often traumatic experiences before, during, and after their flight and socio-structural post-migration stressors, refugees are potentially vulnerable to hazardous substance use. They form a structurally disadvantaged group for substance use prevention and intervention. Various barriers make it difficult for them to access the healthcare system and to get health information. Therefore, a participatory multi-component prevention concept for refugees in shared accommodations was developed. The aim of the trial is to evaluate the efficacy of this concept regarding the increase in knowledge about substance use among refugees living in shared accommodations.

Methods

Based on a randomized controlled stepped-wedge design, the study will be conducted in a multicenter setting in nine shared accommodations and will aim to include refugees living in shared accommodations as well as social workers and psychologists working there.

Discussion

This trial will be one of the first to generate evidence about effective participatory prevention concepts for refugees in shared accommodations. Evidence-based concepts for refugees can improve access to health care and might be helpful for the multidisciplinary workforce in shared accommodations.

Trial registration

OSF Registry: osf.io/ebnj3. Registered on May 24, 2024. Registration DOI: https://doi.org/10.17605/OSF.IO/EBNJ3.
Neck masses- a study of clinico-epidemiological and cytological profile
Authors: Thakur Chandan Kumari , Dhasmana Gunjan , Bhardwaj Heemani , Vindrani Nehal
Published: November 2024

Background

Swellings of the neck are a common presentation encountered by surgeons in outpatient settings, often prompting early medical attention due to their visibility and potential cosmetic concerns. Neck masses can range from reactive lymphadenitis to malignant lesions.

Aim of the study

This observational study aimed to investigate the clinical profile and etiopathology of neck masses within the Indian population.

Methods

Over a six-month period, patients presenting with neck swellings at the Department of ENT in a multi-speciality government hospital, Delhi, were included. 100 patients were included in the study. Detailed demographic data and presenting symptoms were recorded, along with local examination findings and cytological analysis using fine needle aspiration cytology (FNAC).

Results

The study population predominantly consisted of individuals aged 21 to 30 (30%) and 11 to 20 (22%), with females comprising 68% of the total, male to female ratio being 0.6:1. The most common etiologies observed were infective or inflammatory (42%), followed by thyroid-related conditions (35%). Tubercular lymphadenitis was the most common among infective etiology, accounting for 36% of these cases. Notable variations were observed across age groups, with younger demographics showing higher prevalence of benign and inflammatory conditions, while older individuals presented with diverse etiologies including thyroid nodules and salivary gland tumors.

Conclusion

The age distribution data of patients presenting with neck masses provides valuable insights into the epidemiology and etiology of such conditions across different age groups. FNAC remains a valuable and cost-effective diagnostic tool for evaluating superficial and deep-seated lesions in the head and neck region. It offers reliable categorization of lesions due to its high sensitivity and specificity.
Frequency-dependent nonlinear amplitude-variation-with-offset inversion for fluid mobility in viscoelastic media
Authors: Zheng Xuan , Zong Zhaoyun
Published: November 2024

Reservoir fluid mobility is defined as the ratio of rock permeability to fluid viscosity, which is an important attribute to guide the prediction of high-quality oil and gas reservoirs. Frequency-dependent amplitude-variation-with-offset (AVO) inversion, based on viscoelastic theory, is a useful tool for fluid identification. In conventional prestack inversion, linear approximations are usually used to calculate the reflection coefficients, whereas nonlinear inversions are only occasionally carried out. However, the nonlinear equation for the reflection coefficient, derived from the exact Zoeppritz equation, has higher accuracy and fewer assumptions than the linear approximations. Therefore, we derive a nonlinear frequency-dependent reflection coefficient equation of the PP wave in terms of P-wave velocity reflectivity, S-wave velocity reflectivity, and fluid mobility, based on the relationship among fluid mobility, incident angle, and seismic wave frequency. We consider viscoelastic media and frequency-dependent responses to improve the authenticity of the reflection coefficients. In addition, we develop a split-step inversion method for fluid mobility based on the artificial neural network inversion algorithm. Synthetic and field data examples demonstrate that our split-step inversion method outperforms traditional inversion methods that rely on approximate equations for predicting underground reservoirs, improving the stability of fluid mobility parameter inversion.
Uptake of Aspirin Chemoprevention in Patients With Lynch Syndrome
Authors: Singhal Sachi , Riggs Emma D. , Ruth Karen J. , Chavez-Salas Juan Pablo , Chertock Yana , Daly Mary B. , Hall Michael J.
Published: November 2024

PURPOSE

Individuals with Lynch syndrome (LS) are at a high lifetime risk of colorectal cancer (CRC) and other cancers. Aspirin (ASA), a nonsteroidal anti-inflammatory drug (NSAID), has proven chemopreventive benefits in LS, with the CAPP2 randomized double-blind placebo-controlled trial demonstrating a 60% relative risk reduction for CRC among participants who adhered to ASA for 2 years or more. This study sought to characterize uptake of ASA/NSAIDs among individuals with LS and to understand factors associated with use.

METHODS

Individuals with LS were invited (June 2020-August 2022) to complete a one-time electronic survey about LS screening behaviors, uptake of ASA/NSAIDs, and current/emerging cancer prevention options. Participants were recruited from the Fox Chase Cancer Center (FCCC) Risk Assessment Program Registry and through a research invitation posted to two patient-facing LS advocacy websites.

RESULTS

Two hundred and ninety-six participants completed the survey including 116 (39.2%) from FCCC and 180 (60.8%) recruited via the Internet, including 14.9% non-US based individuals. Uptake of regular ASA or NSAIDs was modest at 34.8% and was even lower (25.7%) when focusing on individuals taking ASA or NSAIDs solely for chemoprevention of LS. More than half (55%) were taking <100 mg ASA daily. In multivariable modeling, lower perceived threat of LS (odds ratio [OR], 0.84 [95% CI, 0.72 to 0.98]), lower
concern for side effects
(OR, 0.86 [95% CI, 0.76 to 0.99]), and higher
likelihood of recommending ASA/NSAIDs to family or a friend
were all associated with ASA/NSAIDs use (OR, 1.70 [95% CI, 1.37 to 2.10]).

CONCLUSION

Uptake of ASA/NSAIDs chemoprevention is modest among individuals with LS. Patient perceptions of the pros and cons of ASA, more so than demographic and disease-related factors, were associated with chemoprevention uptake.
Παραγωγή και εκμετάλλευση συστατικών υψηλής προστιθέμενης αξίας από παραπροϊόντα ελαιοτριβείου
Authors: Παπαχριστόπουλος Ευστάθιος
Published: November 2024

Το ελαιόλαδο, όπως είναι γνωστό, έχει σημαντικό ρόλο στη διατροφή των μεσογειακών λαών και αναγνωρίζεται ως πολύτιμη πηγή φυσικών φαινολικών αντιοξειδωτικών.Οι πολυφαινόλες παρουσιάζουν προστατευτικές ιδιότητες λόγω της αντιοξειδωτικής τους δράσης, ως σαρωτές ελεύθερων ριζών ή ως αποικοδομητές οξειδωτικών αλυσιδωτών αντιδράσεων. Η δράση αυτή εκδηλώνεται με την προστασία της LDL από την οξείδωση, η οποία συνεπάγεται μείωση της ποσότητας της χοληστερόλης που εναποτίθεται στους ιστούς, αλλά και με τη δράση της έναντι οξειδωτικών παραγόντων στον επιθηλιακό ιστό, μειώνοντας έτσι τις πιθανότητες σχηματισμού αθηρωματικής πλάκας και συνεπώς μειώνοντας τον κίνδυνο καρδιαγγειακής νόσου. Συμπερασματικά, η ανάκτηση πολυφαινολών, προϊόν υψηλής προστιθέμενης αξίας, από τα τριφασικά υγρά απόβλητα των ελαιοτριβείων και η δυσκολία βιοαπαδόμησής τους λόγω του αντιοξειδωτικού τους χαρακτήρα, απαιτούν μια αποτελεσματική μέθοδο επεξεργασίας χωρίς αυτή να οδηγεί στη καταστροφή των πολύτιμων πολυφαινολών. Συγκεκριμένα, επιχειρείται η ανάκτηση πολυφαινολών από τα τριφασικά υγρά απόβλητα των ελαιοτριβείων με προσρόφηση, χρησιμοποιώντας για πρώτη φορά ως προσροφητικά υλικά, υποπροϊόντα άλλων διεργασιών (φυσικοί ροφητές) χαμηλής αξίας, όπως: τέφρα από φλοιό ρυζιού, φλοιοί ρυζιού, πυρηνόξυλο, ελαιοπυρήνα, ιπτάμενη τέφρα Μεγαλόπολης και ιπτάμενη τέφρα Πτολεμαΐδας.Δεδομένου επίσης ότι: α) το ενεργειακό απόθεμα των κλαδιών ελιάς, το οποίο προέρχεται από την καλλιέργεια του ελαιόδεντρου παραμένει αναξιοποίητο λόγω της καύσης τους στα χωράφια, β) τα φύλλα ελιάς της παραγωγικής διαδικασίας εξαγωγής ελαιόλαδου δεν χρησιμοποιούνται επαρκώς ως εδαφοβελτιωτικό και γ) το πυρηνόξυλο των πυρηνελαιουργείων επίσης χρησιμοποιείται ως καύσιμο υλικό, επιχειρείται ο σχεδιασμός μονάδας συμπαραγωγής ηλεκτρικής και θερμικής ενέργειας από τα παραπάνω υποπροϊόντα μέσω αναερόβιας χώνευσης. Η μελέτη τεχνοοικονομικών και διαχειριστικών θεμάτων για την πλήρη και ολιστική διαχείριση της παραγόμενης ενέργειας από την αναερόβια χώνευση της παραπάνω βιομάζας, ολοκληρώνει το παρόν έργο, ενώ η πιθανότητα τυχόν επενδυτικού ενδιαφέροντος θα ωθήσει στην ανάπτυξη ενός νέου και καινοτόμου μοντέλου παραγωγής και διάθεσης ενέργειας.
Learning from the best: How medical-students construct role models in general practice during the COVID-19 pandemic and what factors influence this process, a qualitative study.
Authors: Sutcliffe Hamish , Odonnell Patrick , Andrews Jane
Published: November 2024

Background Role-modelling has been found to strongly influence speciality choice for medical students either positively or negatively. There is a deficit in recruitment toward general practice, set to exacerbate the shortfall in GP numbers over the coming decade in the face of spiralling demand. In medical school, students acquire knowledge, skills and start to form their professional identity by observation and interaction with medical educators through the process of role-modelling. Given the significance of this process, the present study attempted to explore the “lived experience” of medical students encountering potential role models during their GP placement using a qualitative method. Methods Following a design based upon the principles of Grounded Theory 10 qualitative interviews were conducted with third-year medical student volunteers at Warwick Medical School. Interviews were recorded, transcribed and analysed using theoretical axial coding demonstrating data saturation in key themes. Results Analysis of data gave insights regarding student perception of positive and negative role modelling in three corresponding domains: Personal Attributes, Student Relationship and Patient Relationships. Conclusions The findings offer unique insights into the influence and impact of GP role-modelling on medical student’s experiences and perceptions during a time of the Covid-19 pandemic and the immediate post-pandemic period and add to the wider body of literature by exploring the influences GP role-modelling has on medical student training experience. The findings support easily implementable recommendations to strengthen positive role modelling in the GP medical student placement context.
STRATEGIC THINKING OF FUTURE TEACHERS IN A CHANGING CULTURAL AND EDUCATIONAL SPACE: REFINING THE CONCEPTUAL FRAMEWORK
Authors: Shevchenko Yuriy V.
Published: November 2024

Working with future teachers in new regions of the Russian Federation demonstrates the urgent need to update educational programs, fill social and educational trainings with new meanings, and form the content of education at universities. In this view, the elaboration of a system for the development of strategic thinking of future teachers, designed to interest them and ensure a high-quality educational process, is extremely in demand in the region due to the acute shortage of teaching staff.
The purpose of the study in the research is to reveal the basic concepts concerning the strategic thinking of future teachers, to formulate a value core to determine the basic life and professional concept of a future teacher for the development of this type of mental activity, taking into account the changing cultural and educational space.
Method and methodology. In the research, procedural and activity–based approaches are used to disclose and analyze the basic concepts; three main approaches (procedural, activity-based, value-based) are used to formulate the concept of «strategic thinking» in a narrow, broad and global sense. The main research methods are analysis, synthesis, induction, and deduction.
Results. As the results of the study there is the conceptual basis for discussion to elaborate a system for the development of strategic thinking of future teachers in a changing cultural and educational space and there is also a model of the strategy of the future teacher.
Scope of the results. The system of developing strategic thinking of future teachers will improve educational activities with students. Elaborated taking into account achievements in world and domestic psychological and pedagogical science and practice, this system will allow you to review and make the necessary changes to educational programs, social and educational trainings, educational, cultural and leisure activities with students.
CREATION OF A QUASI-PROFESSIONAL TECHNOLOGICALLY SATURATED ENVIRONMENT BASED ON THE RESOURCES OF A TECHNOPARK AT A PEDAGOGICAL UNIVERSITY
Authors: Aranova Svetlana V. , Borovik Lyudmila K. , Iglina Elena A. , Primchuk Nadezhda V.
Published: November 2024

Background. Analysis of studies devoted to the activities of technology parks reveals a trend of increasing their importance for the formation of students' general professional competencies in the infrastructure of pedagogical universities. Currently, pedagogical universities have basic conditions that allow creating a quasi-professional environment consistent with the technologically rich environment of a modern school. At the same time, a number of socio-cultural factors predetermine the need to prepare students to solve increasingly complex pedagogical problems in the context of a changing educational environment and expanding interactions.
Purpose - development of ways to improve the basic conditions existing in a pedagogical university in order to create a quasi-professional, technologically rich educational environment taking into account modern influences.
Materials and methods. The local pedagogical experience of the Herzen State Pedagogical University departments on the use of technopark resources in the professional training of students of different profiles was studied. The study involved 162 students and 22 scientific and pedagogical staff. The following research methods were used: theoretical analysis, analysis of local pedagogical experience, included pedagogical observation, survey.
Results. The components of quasi-professional environment are identified and the basic conditions for its creation in a teacher training university by filling the components according to the characteristics of technologically rich educational environment of a modern school are deduced. The problems of organizational, methodical, motivational and semantic character, which hinder the creation of quasi-professional environment in the pedagogical university, are revealed. The solution to change the conditions for the creation of such a method by means of its level structuring; educational procedural tasks with the use of technopark resources; development of attitudes of the general cultural and universal plan, determining the features of interaction between the subjects of the educational process in a quasi-professional environment is proposed.
Financing. The research is carried out at the expense of an internal grant from the A. I. Herzen State Pedagogical University (Project No. 31).
CONDITIONS FOR FORMING THE ABILITY OF PEDAGOGICAL STUDENTS TO USE MIND MAPS IN PEDAGOGICAL WORK
Authors: Shestakova Lidia G. , Lapenok Marina V.
Published: November 2024

Background. In conditions of a large information flow and accessibility of information, problems often arise related to the ability to process it, analyze it, and optimally memorize it. One of these tools is mind maps, which in this study were considered as didactic means of structuring, ordering, visualization, systematization, and establishing relationships.
Purpose: to identify the conditions for developing students’ ability to use mind maps in teaching activities.
Materials and methods. The study is of a theoretical and empirical nature. The identified conditions were introduced into the student learning process during experimental work. As part of the ability to use mind maps in teaching activities: knowledge of theoretical material on mind maps, requirements for them, capabilities and limitations; the ability to draw up mind maps, including using digital resources; include mind maps in work with schoolchildren. The study used a complex of theoretical and empirical methods. To check the reliability of the results obtained, the Wilcoxon T-test was used.
Results. The conditions for developing students' ability to use mind maps in teaching activities are identified: embedding mind maps as a meaningful line into disciplines and practices; inclusion in the educational process of working with ready-made maps, checking their correctness, addition and/or adjustment, development, use of maps in the design and research work of the teacher and student; inclusion of tasks for working with mind maps in the program of teaching practice, with their subsequent defense. With the help of experimental work, the effectiveness of the identified conditions for developing students’ ability to use mind maps in teaching activities has been proven.
UNIVERSITY ENVIRONMENT AS AN ADAPTATION FACTOR OF INTERNATIONAL STUDENTS IN RUSSIA
Authors: Grishina Galina V.
Published: November 2024

Background. Internationalisation of education defines the route of modern universities. They need to solve problems related to attracting international students, maintaining the number of them and providing pedagogical support for their adaptation. Universities have to create effective pedagogical conditions that facilitate the adaptation of international students. The specialists study the factors influencing this process, and one of the factors is the university environment.
Purpose. The purpose is to study the university environment as a factor in the adaptation of international students and identify its components from the adaptation barriers aspect.
Materials and methods. At the theoretical stage, scientific papers have been analyzed, and at the practical stage, the methods of conversation and questioning have been used.
Results. The university environment is a space where all participants in the educational process interact. It has powerful potential for the upbringing and development of personality. It is possible to consider the university environment as an external factor influencing the adaptation process of international students. The university environment should be understood as a system of barrier-forming components: biological, cultural, social, academic, organizational and managerial, financial and economic, linguistic, communicative and socio-psychological. Gradual acceptance of the components results in accepting the university environment as a whole.
RESULTS OF SUBJECT-LANGUAGE TRAINING AT THE UNIVERSITY
Authors: Lubozheva Lionella N.
Published: November 2024

Background. The timeliness of this work is caused by the needs of modern society associated with various changes in different spheres of society, to a greater extent in industrial, social, and economic, which makes us take a fresh look at the language training of future specialists. In modern realities, there is a clear need for an interdisciplinary tandem to correctly form speech skills, knowledge in the professional field and make it possible in the future to put them into practice in professional activities, which, in turn, is a real difficult task for teachers and methodologists. Unfortunately, traditional methods are not always able to solve the dilemmas of modern society, while innovative hikes are able to cope with the task. In the presented work to solve the problem, subject-language integrated training is used
The purpose is to present the stages of integration of language and profile disciplines and demonstrate the upshot of the enforcement of studied approach in the educational practice of the universities.
Methods: general scientific (review and analysis of theoretical materials, synthesis and deduction) and private-scientific (testing, observation and questioning).
Results. The work clarifies such definitions as "subject-language integrated training," "communication technologies" and "professional interaction," presents and illustrates the data of analysis of the application of subject-language integrated learning in foreign language classes for students of the 1st year of the faculty of Economics and offers conclusions about the work done.
Conclusion. The use of a set of exercises created on subject-language integrated training facilitates the formation of linguistic professional interaction in the university and makes this process more effective. Moreover, it is considered expedient to develop a course for the specialty "Economic Security" studied approach, as well as the adaptation of digital technologies and online platforms to support subject-language integrated training.
PERSONAL AND PROFESSIONAL FOREIGN LANGUAGE COMPETENCE FORMATION AMONG FUTURE TEACHING STAFF IN THE E-LEARNING CONTEXT
Authors: Mirontseva Svetlana S. , Baiko Valeria A. , Spirina Yuliya P.
Published: November 2024

Background. The article discusses the benefits of online education in the university environment. The demand for e-learning is due to the formation of the intellectual and creative potential of the individual for creative activity in the professional field.
Purpose. The purpose of this study is to present the experience of implementation the electronic training course “Foreign Language in Education” for students in the field of training 44.03.05 Pedagogical Education.
Materials and methods. The article considers the results of the pilot work on the introduction of the electronic educational course “Foreign Language in Education” into the educational process of the university for students in the field of training 44.03.05 Pedagogical education. The authors present the dynamics of changes in the levels of personal and professional foreign language competence formation of future teachers at various stages of the experiment. This study required the use of a set of complementary research methods: theoretical - study and analysis of pedagogical and scientific-methodical literature; Federal State Educational Standard of Higher Education; generalization, comparison; empirical - study and generalization of pedagogical experience, pedagogical experiment, statistical processing of the experimental results.
Results. The pedagogical experiment was conducted in several stages: motivational and familiarization, communicative and productive, professional and reflective. The experiment involved 270 second-year students of the Humanitarian and Pedagogical Institute of Sevastopol State University. Positive dynamics of changes in the levels of f personal and professional foreign language competence formation of future teaching staff in the context of e-learning at various stages of the experiment are observed. The results obtained during the experiment demonstrate a significant increase in the level of formation of personal and professional foreign language competence of future teaching staff of the experimental group.
PSYCHOBIOGRAPHIC CHARACTERISTICS, SEMANTIC ORIENTATIONS OF STUDENTS OF RUSSIAN AND TATAR NATIONALITIES
Authors: Akhmerov Rashad A. , Khakimova Nailya G.
Published: November 2024

Background. This is due to the fact that studies of biography and psychobiography allow us to reveal the features and patterns of the life path, in practice to provide psychological assistance to a person in search of himself, his life path, in optimal self-realization. This is especially true in today's rapidly changing world, when a person has to change his place of residence, profession, habits during his life, and adapt to changing life circumstances.
Purpose. The aim is to identify differences and peculiarities of the relationship between indicators of psychobiographic characteristics and life orientations among students of Russian and Tatar nationalities.
Materials and methods. Causometry, evaluation of five-year intervals, test of resilience, test of life orientations. The sample of the study was made up of students of Russian and Tatar nationalities studying at Naberezhnye Chelny State Pedagogical University. The samples are balanced by sexual dimorphism and representation from urban and rural areas.
Results. Differences in psychobiographic characteristics between students of Russian and Tatar nationalities have been revealed. Students of Russian nationality are going to live less, feel older than their chronological age. Students of Tatar nationality see difficulties in life planning, they have more motivating factors for life than students of Russian nationality. There were no differences in life orientations and resilience. Students of Russian nationality have a greater integration of psychobiographic characteristics with life orientations than students of Tatar nationality. The results of the correlation analysis confirm the validity of measuring the subjective productivity of life by the criterion of "degree of saturation with significant events" and the value concept of life events and life scenarios.
PSYCHOLOGICAL RESILIENCE OF CORRECTIONAL OFFICERS: REVIEW OF FOREIGN RESEARCH
Authors: Kislyakov Pavel A. , Tsvetkova Nadezhda A.
Published: November 2024

Background. Employees of correctional institutions of the penal system in any country of the world are at risk of sudden increase in workplace stress, which creates the need for a scientific search for personal resources that ensure their mental health and emotional and psychological well-being. Experience has been gained abroad in researching the psychological resilience of prison staff as a predictor of mental health and a protector of burnout. The purpose of this article is to present an overview of foreign publications devoted to the study of the psychological resilience of employees of the penitentiary system, based on a systematic approach to the analysis of factors (predictors) of its development and their diagnosis.
Research methods. Articles were searched in international databases (Web of Science, Scopus, Semantic Scholar) with subsequent content analysis. The content analysis was aimed at systematizing occupational risk factors and factors (predictors) of the development of psychological resilience of employees of the penitentiary system, methods for diagnosing psychological resilience and the state of psychological resilience.
The results of the study specify approaches to the definition and study of the psychological resilience of employees of the penitentiary system of the United States, Great Britain, China, and Nigeria. Environmental and intrapersonal factors (predictors) of psychological resilience are generalized. The results obtained can be used in Russia in the study of the psychological resilience of employees of the penitentiary system and the implementation of special programs of professional psychological guidance.
THE FAMILY EDUCATION FORM IN THE ESTIMATION OF PARENTS AND RESULTS OF CHILDREN’S SOCIALISATION
Authors: Chukmarova Lucia F.
Published: November 2024

Background. Nowadays the family education is getting popular in Russia. It important to investigate reasons of this trend: disadvantages, advantages and consequences of it.
Purpose. To determine reasons of choosing the family education from parent's side, explore their advantage and disadvantage, as well as investigate aspects of the socialisation of children who are in the family education.
Materials and methods. In the research were involved parents, who prefer family or traditional education as well as children who are on family or traditional education. Parents were interviewed via the questionnaire of K.V. Zhuikova, S.V. Lyalikova "Family and home schooling as a model of education, the future". Children were tested by the methodology of diagnosing the socio-psychological adaptation of K. Rogers and R. Diamond.
Results. Parents prefer the family education due to the low quality of the traditional education, intention to save children's health, supporting the attachment to parents and stressful conditions at school. They appreciate individual approach, flexible schedule and the time that the family education provide. They confident that the study is more important that estimations. The disadvantages of the family education are the lack of team-work experience, low level of socialisation. Meanwhile parents who prefer traditional education are more critical to this disadvantages. The criteria of choosing the traditional education based on such values as health, family well-being, independence, freedom in life, creative development and self-development. The parents who prefer the traditional education tends to choose the school uniform since they value achievements. Children from the traditional education have the high level of socialisation, they accept themself and others, have the less level of emotional discomfort (in comparing with children from the family education, who have dominate internal control and intention to domination.
„Officium a rationibus”. Studium z dziejów administracji rzymskiej w okresie pryncypatu
Authors: Kłodziński Karol
Published: November 2024

Fenomen istnienia wielkich imperiów, w tym Cesarstwa Rzymskiego, cieszy się niesłabnącym zainteresowaniem uczonych. Do dziś nie do końca rozpoznane pozostaje zagadnienie funkcjonowania administracji rzymskiej w okresie pryncypatu. Kolejnym pokoleniom badaczy przychodzi zmierzyć się z pytaniami, jak były zorganizowane struktury administracyjne tak rozległego imperium, w jakim sposób było ono zarządzane, kim byli urzędnicy cesarscy i jakie posiadali kompetencje. Książka „Officium a rationibus”. Studium z dziejów administracji rzymskiej w okresie pryncypatu została poświęcona urzędowi „a rationibus” („do spraw rachunkowości/od rachunków”), głównej centralnej instytucji zarządzającej finansami wczesnego Cesarstwa Rzymskiego, oraz urzędnikom, którzy piastowali to stanowisko. Studium to nie tylko prezentuje jeden z najważniejszych elementów administracji wczesnego Cesarstwa, lecz także daje cenny wgląd w funkcjonowanie tejże administracji jako całości. Urząd „a rationibus”, choć opisywany przez uczonych już od XIX wieku, do dziś nie doczekał się osobnego opracowania monograficznego. Odkrywane i publikowane niemal każdego roku źródła epigraficzne, a także potrzeba reinterpretacji tych dobrze już znanych źródeł (głównie narracyjnych) oraz narosłych w historiografii opinii, skłaniają do nowego spojrzenia na funkcjonowanie „officium a rationibus” w okresie pryncypatu.
Role of Nutrition and Hydration in Injury Prevention and Recovery: A Review
Authors: Chodkowski Jakub
Published: November 2024

Introduction and Purpose: Nutrition and hydration play critical roles in supporting athletic performance, injury prevention, and effective recovery, impacting both amateur and elite athletes. This literature review explores current evidence on nutritional and hydration strategies that promote musculoskeletal health, reduce injury risk, and optimize recovery following injury.
Material and Methods: A comprehensive literature review was conducted using the PubMed and Google Scholar databases, focusing on articles published up until the end of 2023. Keywords used in the search included: “nutrition strategies”, “hydration”, “injury prevention”, “nutrition” and “recovery”. Articles were selected based on their relevance to the topic and quality of evidence.
Results: The review reveals that hydration plays a critical role in reducing the risk of injury and optimizing recovery. Dehydration is associated with increased muscle fatigue, cramps, and a greater likelihood of heat-related injuries, impairing physical performance. Furthermore, nutritional strategies, particularly protein intake post-exercise, are essential for muscle recovery, reducing inflammation, and speeding up the healing process.
Conclusions: Implementing appropriate dietary strategies, including adequate hydration, balanced macronutrient intake, and electrolyte replenishment, can significantly reduce the risk of injury, enhance performance, and accelerate recovery times.
Open relationships – challenges and dilemmas
Authors: Wdowiak Krystian , Maciocha Agnieszka , Wąż Julia , Witas Aleksandra , Chachaj Weronika , Słomka Paulina , Gardocka Ewa
Published: November 2024

Introduction and objective: Consensual non-monogamy (CNM) refers to various relationship types in which at least one partner, with the other’s consent, forms sexual and/or emotional connections with other people. In open relationships, partners are allowed to engage sexually with others, but emotional intimacy is reserved for the primary relationship, which takes precedence. The aim of this article is to gather the most up-to-date information on open relationships.Material and methods: A review of studies available on the PubMed platform (https://pubmed.ncbi.nlm.nih.gov/) was conducted, including articles with free full-text access that used the keywords: “open relationship”, “CNM” and "Consensual non-monogamy."Brief Description of the State of Knowledge: CNM includes open relationships, polyamory, polyfidelity, and swinging. Interest in open relationships has increased in recent years, with more people expressing curiosity about them than those actively participating. Men, individuals with high cognitive empathy, those less prone to jealousy, and those capable of experiencing compersion—the joy from a partner’s involvement with others—are particularly interested in open relationships. Summary:  Research suggests potential benefits of CNM, including greater relationship and sexual satisfaction compared to monogamous arrangements. However, open relationships can also pose challenges such as social stigma, the potential breakdown of the primary relationship, or complications in parenting for those involved. Despite growing interest, CNM and phenomena like compersion remain under-researched, providing an open field for further investigation into their dynamics and impact on individual and relational well-being.