bluuebunny/crossref_metadata_2025 huggingface dataset:
Development of a Portfolio Diet Score and Its Concurrent and Predictive Validity Assessed by a Food Frequency Questionnaire
Authors: Glenn Andrea , Boucher Beatrice , Kavcic Chloe , Khan Tauseef , Paquette Melanie , Kendall Cyril , Hanley Anthony , Jenkins David , Sievenpiper John
Published: August 2021

The Portfolio Diet, a plant-based portfolio of cholesterol-lowering foods, has been shown to reduce low-density lipoprotein cholesterol (LDL-C), and other cardiovascular risk factors, in randomized controlled trials (RCTs). It is not known if these beneficial effects translate to a lower incidence of cardiovascular disease (CVD). To support examinations between Portfolio Diet adherence and disease, a Portfolio Diet score (PDS) was developed and its predictive and concurrent validity was assessed within the Toronto Healthy Diet Study, a six-month RCT in overweight adults. Predictive validity was assessed using change in the PDS measured by food frequency questionnaire (FFQ) and concomitant change in LDL-C from baseline to six months using multiple linear regression, adjusted for potential confounders (n = 652). Concurrent validity was assessed in a subset of participants (n = 50) who completed the FFQ and a 7-day diet record (7DDR) at baseline. The PDS determined from each diet assessment method was used to derive correlation coefficients and Bland–Altman plots to assess the between-method agreement. The change in PDS was inversely associated with change in LDL-C (β coefficients: −0.01 mmol/L (95% confidence intervals (CIs): −0.02, −0.002; p = 0.02). The correlation between the PDS from the FFQ and 7DDR was 0.69 (95% CIs: 0.48, 0.85). The Bland–Altman plot showed reasonable agreement between the score from the FFQ and 7DDR. These findings indicate predictive validity of the PDS with lower LDL-C, and reasonable concurrent validity of the PDS as assessed by an FFQ against a 7DDR.
The History of Anti-Trypanosome Vaccine Development Shows That Highly Immunogenic and Exposed Pathogen-Derived Antigens Are Not Necessarily Good Target Candidates: Enolase and ISG75 as Examples
Authors: Magez Stefan , Li Zeng , Nguyen Hang Thi Thu , Pinto Torres Joar Esteban , Van Wielendaele Pieter , Radwanska Magdalena , Began Jakub , Zoll Sebastian , Sterckx Yann G.-J.
Published: August 2021

Salivarian trypanosomes comprise a group of extracellular anthroponotic and zoonotic parasites. The only sustainable method for global control of these infection is through vaccination of livestock animals. Despite multiple reports describing promising laboratory results, no single field-applicable solution has been successful so far. Conventionally, vaccine research focusses mostly on exposed immunogenic antigens, or the structural molecular knowledge of surface exposed invariant immunogens. Unfortunately, extracellular parasites (or parasites with extracellular life stages) have devised efficient defense systems against host antibody attacks, so they can deal with the mammalian humoral immune response. In the case of trypanosomes, it appears that these mechanisms have been perfected, leading to vaccine failure in natural hosts. Here, we provide two examples of potential vaccine candidates that, despite being immunogenic and accessible to the immune system, failed to induce a functionally protective memory response. First, trypanosomal enolase was tested as a vaccine candidate, as it was recently characterized as a highly conserved enzyme that is readily recognized during infection by the host antibody response. Secondly, we re-addressed a vaccine approach towards the Invariant Surface Glycoprotein ISG75, and showed that despite being highly immunogenic, trypanosomes can avoid anti-ISG75 mediated parasitemia control.
Relationship between Latent Toxoplasmosis and Depression in Clients of a Center for Assisted Reproduction
Authors: Hlaváčová Jana , Flegr Jaroslav , Fiurašková Kateřina , Kaňková Šárka
Published: August 2021

Latent infection of the globally spread parasite Toxoplasma gondii in humans has been associated with changes in personality and behavior. Numerous studies have investigated the effect of toxoplasmosis on depression, but their results are inconsistent. Our study focused on the effect of latent toxoplasmosis on depression in men and women in association with their fertility. In 2016–2018, we recruited clients (677 men and 664 women) of the Center for Assisted Reproduction and asked them to complete a standardized Beck Depression Inventory-II. In women without fertility problems, we found higher depression scores in Toxoplasma-positive than in Toxoplasma-negative (p = 0.010, Cohen’s d = 0.48). Toxoplasma-positive infertile men, on the other hand, had lower depression scores than Toxoplasma-negative infertile men (p ≤ 0.001, Cohen’s d = 0.48). Our results are consistent with the previously described effects of latent toxoplasmosis, which seem to go in opposite directions regarding the effect on personality and behavior of men and women. Our results could be explained by gender-contrasting reactions to chronic stress associated with lifelong infection. This suggests that due to gender differences in the impact of latent toxoplasmosis, future studies ought to perform separate analyses for women and men.
New 2,3-Benzodiazepine Derivative: Synthesis, Activity on Central Nervous System, and Toxicity Study in Mice
Authors: Amaghnouje Amal , Bohza Serhii , Bohdan Nathalie , Es-Safi Imane , Kyrylchuk Andrii , Achour Sanae , El Fatemi Hinde , Bousta Dalila , Grafov Andriy
Published: August 2021

We report the design and synthesis of a new diazepine derivative, 4-(4-methoxyphenyl)-2,3,4,5-tetrahydro-2,3-benzodiazepin-1-one (VBZ102), and the evaluation of its anxiolytic-like profile, memory impairment effect, and toxicity in Swiss mice. VBZ102 was evaluated for central nervous system effects in an open field, light–dark box, and novel object recognition tests under oral administration for acute and sub-acute treatment. We tested the VBZ102 toxicity in mice through a determination of LD50 values and examination of the biochemical and histopathological parameters. The VBZ102 induced an anxiolytic effect at different doses both in the light–dark box and open field tests. Unlike other benzodiazepines (e.g., bromazepam), a sedative effect was noted only after administration of the VBZ102 at 10.0 mg/kg.
Ruthenium Complexes: An Alternative to Platinum Drugs in Colorectal Cancer Treatment
Authors: Mahmud Kazi Mustafa , Niloy Mahruba Sultana , Shakil Md Salman , Islam Md Asiful
Published: August 2021

Colorectal cancer (CRC) is one of the intimidating causes of death around the world. CRC originated from mutations of tumor suppressor genes, proto-oncogenes and DNA repair genes. Though platinum (Pt)-based anticancer drugs have been widely used in the treatment of cancer, their toxicity and CRC cells’ resistance to Pt drugs has piqued interest in the search for alternative metal-based drugs. Ruthenium (Ru)-based compounds displayed promising anticancer activity due to their unique chemical properties. Ru-complexes are reported to exert their anticancer activities in CRC cells by regulating different cell signaling pathways that are either directly or indirectly associated with cell growth, division, proliferation, and migration. Additionally, some Ru-based drug candidates showed higher potency compared to commercially available Pt-based anticancer drugs in CRC cell line models. Meanwhile Ru nanoparticles coupled with photosensitizers or anticancer agents have also shown theranostic potential towards CRC. Ru-nanoformulations improve drug efficacy, targeted drug delivery, immune activation, and biocompatibility, and therefore may be capable of overcoming some of the existing chemotherapeutic limitations. Among the potential Ru-based compounds, only Ru (III)-based drug NKP-1339 has undergone phase-Ib clinical trials in CRC treatment.
When Cyclodextrins Met Data Science: Unveiling Their Pharmaceutical Applications through Network Science and Text-Mining
Authors: Rincón-López Juliana , Almanza-Arjona Yara C. , Riascos Alejandro P. , Rojas-Aguirre Yareli
Published: August 2021

We present a data-driven approach to unveil the pharmaceutical technologies of cyclodextrins (CDs) by analyzing a dataset of CD pharmaceutical patents. First, we implemented network science techniques to represent CD patents as a single structure and provide a framework for unsupervised detection of keywords in the patent dataset. Guided by those keywords, we further mined the dataset to examine the patenting trends according to CD-based dosage forms. CD patents formed complex networks, evidencing the supremacy of CDs for solubility enhancement and how this has triggered cutting-edge applications based on or beyond the solubility improvement. The networks exposed the significance of CDs to formulate aqueous solutions, tablets, and powders. Additionally, they highlighted the role of CDs in formulations of anti-inflammatory drugs, cancer therapies, and antiviral strategies. Text-mining showed that the trends in CDs for aqueous solutions, tablets, and powders are going upward. Gels seem to be promising, while patches and fibers are emerging. Cyclodextrins’ potential in suspensions and emulsions is yet to be recognized and can become an opportunity area. This is the first unsupervised/supervised data-mining approach aimed at depicting a landscape of CDs to identify trending and emerging technologies and uncover opportunity areas in CD pharmaceutical research.
Advances in Cereal Crops Breeding
Authors: Loskutov Igor G.
Published: August 2021

Cereals are the main food and feed crops on our planet, with wheat, rice, and maize occupying three-quarters of the total acreage [...]
Genomic Variation and Diversification in Begomovirus Genome in Implication to Host and Vector Adaptation
Authors: Nigam Deepti
Published: August 2021

Begomoviruses (family Geminiviridae, genus Begomovirus) are DNA viruses transmitted in a circulative, persistent manner by the whitefly Bemisia tabaci (Gennadius). As revealed by their wide host range (more than 420 plant species), worldwide distribution, and effective vector transmission, begomoviruses are highly adaptive. Still, the genetic factors that facilitate their adaptation to a diverse array of hosts and vectors remain poorly understood. Mutations in the virus genome may confer a selective advantage for essential functions, such as transmission, replication, evading host responses, and movement within the host. Therefore, genetic variation is vital to virus evolution and, in response to selection pressure, is demonstrated as the emergence of new strains and species adapted to diverse hosts or with unique pathogenicity. The combination of variation and selection forms a genetic imprint on the genome. This review focuses on factors that contribute to the evolution of Begomovirus and their global spread, for which an unforeseen diversity and dispersal has been recognized and continues to expand.
Aqueous Extract from Leaves of Citrus unshiu Attenuates Lipopolysaccharide-Induced Inflammatory Responses in a Mouse Model of Systemic Inflammation
Authors: Nishi Kosuke , Ito Takako , Kadota Ayumu , Ishida Momoko , Nishiwaki Hisashi , Fukuda Naohiro , Kanamoto Naoaki , Nagata Yoko , Sugahara Takuya
Published: August 2021

Inflammation is related to various life-threatening diseases including cancer, neurodegenerative diseases, and metabolic syndrome. Because macrophages are prominent inflammatory cells, regulation of macrophage activation is a key issue to control the onset of inflammation-associated diseases. In this study, we aimed to evaluate the potential anti-inflammatory activity of Citrus unshiu leaf extract (CLE) and to elucidate the mechanism underlying its anti-inflammatory effect. We found the inhibitory activity of CLE on the secretion of proinflammatory cytokines and a chemokine from mouse macrophage-like RAW 264.7 cells and mouse peritoneal macrophages. The inhibitory activity of CLE was attributed to downregulated JNK, p38 MAPK, and NF-κB signaling pathways, leading to suppressed gene expression of inflammation-associated proteins. Oral administration of CLE significantly decreased the serum level of proinflammatory cytokines IL-6 and TNFα and increased that of anti-inflammatory cytokine IL-10 in lipopolysaccharide-induced systemic inflammation mice. In addition, oral administration of CLE decreased secretion and gene expression of several proinflammatory proteins in the liver and spleen of the model mice. Overall results revealed that C. unshiu leaf is effective to attenuate inflammatory responses in vitro and in vivo.
Recent Advances in Understanding the Roles of Pectin as an Active Participant in Plant Signaling Networks
Authors: Shin Yesol , Chane Andrea , Jung Minjung , Lee Yuree
Published: August 2021

Pectin is an abundant cell wall polysaccharide with essential roles in various biological processes. The structural diversity of pectins, along with the numerous combinations of the enzymes responsible for pectin biosynthesis and modification, plays key roles in ensuring the specificity and plasticity of cell wall remodeling in different cell types and under different environmental conditions. This review focuses on recent progress in understanding various aspects of pectin, from its biosynthetic and modification processes to its biological roles in different cell types. In particular, we describe recent findings that cell wall modifications serve not only as final outputs of internally determined pathways, but also as key components of intercellular communication, with pectin as a major contributor to this process. The comprehensive view of the diverse roles of pectin presented here provides an important basis for understanding how cell wall-enclosed plant cells develop, differentiate, and interact.
Development of In-Situ Spray for Local Delivery of Antibacterial Drug for Hidradenitis Suppurativa: Investigation of Alternative Formulation
Authors: Wong Yoke Lan , Pandey Manisha , Choudhury Hira , Lim Wei Meng , Bhattamisra Subrat Kumar , Gorain Bapi
Published: August 2021

Hidradenitis suppurativa (HS) has been considered an orphan disease with limited treatments available. The available topical treatment for this condition is clindamycin lotion; however, short retention and frequent application are the main setbacks. Thus, the present study aimed to attain an optimized antibacterial in situ spray formulation for the hidradenitis suppurativa skin condition, which gels once in contact with the skin surface at around 37 °C and possesses bioadhesion as well as sustained-release properties of the incorporated drug. Different concentrations of thermo-reversible gelling polymer, Pluronic F-127, were investigated along with the selected bioadhesive polymers, HPMC and SA. The optimized formulation F3 consisting of 18% Pluronic F-127 with 0.2% HPMC and 0.2% SA was characterized based on various physicochemical properties. The gelation temperature of F3 was found to be 29.0 ± 0.50 °C with a gelation time of 1.35 ± 0.40 min and a pH of 5.8. F3 had the viscosity of 178.50 ± 5.50 cP at 25 °C and 7800 ± 200 cP at 37 °C as the gel set. The optimized formulation was found to be bioadhesive and cytocompatible. Cumulative drug release was 65.05% within the time-frame of 8 h; the release pattern of the drug followed zero-order kinetics with the Higuchi release mechanism. The average zone of inhibition was found to be 43.44 ± 1.34 mm. The properties of F3 formulation reflect to improve residence time at the site of application and can enhance sustained drug release. Therefore, it could be concluded that optimized formulation has better retention and enhanced antimicrobial activity for superior efficacy against HS.
Carbonaceous Materials Coated Carbon Fibre Reinforced Polymer Matrix Composites
Authors: Salahuddin Bidita , Faisal Shaikh N. , Baigh Tajwar A. , Alghamdi Mohammed N. , Islam Mohammad S. , Song Bing , Zhang Xi , Gao Shuai , Aziz Shazed
Published: August 2021

Carbon fibre reinforced polymer composites have high mechanical properties that make them exemplary engineered materials to carry loads and stresses. Coupling fibre and matrix together require good understanding of not only fibre morphology but also matrix rheology. One way of having a strongly coupled fibre and matrix interface is to size the reinforcing fibres by means of micro- or nanocarbon materials coating on the fibre surface. Common coating materials used are carbon nanotubes and nanofibres and graphene, and more recently carbon black (colloidal particles of virtually pure elemental carbon) and graphite. There are several chemical, thermal, and electrochemical processes that are used for coating the carbonous materials onto a carbon fibre surface. Sizing of fibres provides higher interfacial adhesion between fibre and matrix and allows better fibre wetting by the surrounded matrix material. This review paper goes over numerous techniques that are used for engineering the interface between both fibre and matrix systems, which is eventually the key to better mechanical properties of the composite systems.
The Influence of the Ceramic Nanoparticles on the Thermoplastic Polymers Matrix: Their Structural, Optical, and Conductive Properties
Authors: Smaranda Ion , Nila Andreea , Ganea Paul , Daescu Monica , Zgura Irina , Ciobanu Romeo C. , Trandabat Alexandru , Baibarac Mihaela
Published: August 2021

This paper prepared composites under the free membranes form that are based on thermoplastic polymers of the type of polyurethane (TPU) and polyolefin (TPO), which are blended in the weight ratio of 2:1, and ceramic nanoparticles (CNs) such as BaSrTiO3 and SrTiO3. The structural, optical, and conductive properties of these new composite materials are reported. The X-ray diffraction studies highlight a cubic crystalline structure of these CNs. The main variations in the vibrational properties of the TPU:TPO blend induced by CNs consist of the following: (i) the increase in the intensity of the Raman line of 1616 cm−1; (ii) the down-shift of the IR band from 800 to 791 cm−1; (iii) the change of the ratio between the absorbance of IR bands localized in the spectral range 950–1200 cm−1; and (iv) the decrease in the absorbance of the IR band from 1221 cm−1. All these variations were correlated with a preferential adsorption of thermoplastic polymers on the CNs surface. A photoluminescence (PL) quenching process of thermoplastic polymers is demonstrated to occur in the presence of CNs. The anisotropic PL measurements have highlighted a change in the angle of the binding of the TPU:TPO blend, which varies from 23.7° to ≈49.3° and ≈53.4°, when the concentration of BaSrTiO3 and SrTiO3 CNs, respectively, is changed from 0 to 25 wt. %. Using dielectric spectroscopy, two mechanisms are invoked to take place in the case of the composites based on TPU:TPO blends and CNs, i.e., one regarding the type of the electrical conduction and another specifying the dielectric–dipolar relaxation processes.
Impact Response of Aramid Fabric-Reinforced Polybenzoxazine/Urethane Composites Containing Multiwalled Carbon Nanotubes Used as Support Panel in Hard Armor
Authors: Mora Phattarin , Jubsilp Chanchira , Bielawski Christopher W. , Rimdusit Sarawut
Published: August 2021

The aim of this research project is to analyze support panels that are based on aramid fabrics which are reinforced with polybenzoxazine/urethane (poly(BA-a/PU)) composites and contain multiwalled carbon nanotubes (MWCNTs). Through the measurement of mechanical properties and a series of ballistic-impact tests that used 7.62 × 51 mm2 projectiles (National Institute of Justice (NIJ), level III), the incorporated MWCNTs were found to enhance the energy-absorption (EAbs) property of the composites, improve ballistic performance, and reduce damage. The perforation process and the ballistic limit (V50) of the composite were also studied via numerical simulation, and the calculated damage patterns were correlated with the experimental results. The result indicated hard armor based on polybenzoxazine nanocomposites could completely protect the perforation of a 7.62 × 51 mm2 projectile at impact velocity range of 847 ± 9.1 m/s. The results revealed the potential for using the poly(BA-a/PU) nanocomposites as energy-absorption panels for hard armor.
Effects of Biochar on Soil Aggregation and Distribution of Organic Carbon Fractions in Aggregates
Authors: Lee Ming-Hsi , Chang Ed-Haun , Lee Chia-Hsing , Chen Jyun-Yuan , Jien Shih-Hao
Published: August 2021

Soil aggregates are among crucial factors for determining both the quality and erosion resistance of soils. Biochar is a soil amendment that has seen increasing use to improve specific soil properties, mainly the physical structure and the preserving capacity of water and nutrients, as well as sequestration of soil organic carbon. In this study, we applied the rice husk biochar (RHB) and cattle manure compost (COM) in a sandy loam rural soil, which is widely distributed in southern Taiwan, to investigate the combined effects of the biochar and compost on soil aggregation and dynamic change of organic carbon fractions. Through our incubation experiment, both biochar and compost could promote the soil aggregation after eight weeks incubation. The total amounts of macroaggregates (MaAs, >2.0 mm) and mesoaggregates (MeAs, 0.25–2.0 mm) increased by 1.3–9%. During aggregation processes, a considerably greater amount of the soil organic carbon was found to enrich mainly in MaAs and MeAs in all treatments. The COM addition in the soil further promotes organic carbon enrichment in microaggregates (MiAs, <0.25 mm) + fine particles and MeAs after incubation. Increasing labile organic C (LOC) fractions were significantly found in MaAs and MeAs during aggregation processes, whereas decreasing LOC fractions were found in MiAs. The input of fresh organic matter (RHB and COM) initial acts as binding agents in MiAs, and then further enhances the formation of MeAs and MaAs gradually. In conclusion, RHB promotes the physical protection of organic C by increasing soil aggregation and is hence a management option to enhance the C sequestration potential.
Special Issue “Advanced Process Monitoring for Industry 4.0”
Authors: Reis Marco S. , Gao Furong
Published: August 2021

Industry 4 [...]
Ultrasound-Assisted Extraction of Semi-Defatted Unripe Genipap (Genipa americana L.): Selective Conditions for the Recovery of Natural Colorants
Authors: Náthia-Neves Grazielle , Santana Ádina L. , Viganó Juliane , Martínez Julian , Meireles Maria Angela A.
Published: August 2021

Ultrasound-assisted extraction (UAE) of semi-defatted unripe genipap (SDG) using supercritical CO2 was performed to enhance the recovery of natural colorant iridoids genipin and geniposide. There are currently few natural sources of iridoids, and their application as colorants is scarce. The UAE resulted in extracts with blue and green colors using water and ethanol, respectively. The highest global yield and genipin content was recovered with water, and the geniposide was significantly recovered with ethanol. With water at 450 W, the UAE raised the maximum global yield (25.50 g/100 g raw material). At 150 W and 7 min, the maximum content of genipin (121.7 mg/g extract) and geniposide (312 mg/g extract) was recovered. The total phenolic content (TPC) and antioxidant capacity with the oxygen reactive antioxidant capacity (ORAC) assay were also high in aqueous extracts. Ethanolic extracts showed high ferric-reducing ability antioxidant potential (FRAP) values. UAE showed an efficient and fast method to obtain different extracts’ fractions from SDG, which have a wide spectrum of applications, especially as natural food colorants.
Optimization of Process Parameters and Kinetics Analysis of Cd Removal in ZnSO4 Production
Authors: Ren Xiaoling , Shu Xinqian , Li Haisheng , Deng Jiushuai , Li Peng , Qin Sixue
Published: August 2021

In order to optimize the process parameters of Cd removal in the ZnSO4 production process and study the mechanism of Cd removal reaction, the response surface methodology was used to arrange Cd removal experiments and analyze the optimal production conditions, and the mechanism of Cd removal was studied using kinetics. The results show that the optimal process conditions for Cd removal are as follows: reaction temperature 55 °C, reaction time 13.43 min, and the zinc powder dosage should be 2.14 times that of Cd; the main effects of the three variables from large to small are zinc powder dosage, reaction temperature and reaction time; Cd removal is a second-order reaction, and the activation energy of the reaction is 29.6986 kJ/mol, so the reaction conforms to the diffusion control mechanism.
Anaerobic Acidogenic Fermentation of Cellobiose by Immobilized Cells: Prediction of Organic Acids Production by Response Surface Methodology
Authors: Tsafrakidou Panagiota , Tsigkou Konstantina , Bekatorou Argyro , Kanellaki Maria , Koutinas Athanasios A.
Published: August 2021

Response surface methodology was used to derive a prediction model for organic acids production by anaerobic acidogenic fermentation of cellobiose, using a mixed culture immobilized on γ-alumina. Three parameters (substrate concentration, temperature, and initial pH) were evaluated. In order to determine the limits of the parameters, preliminary experiments at 37 °C were conducted using substrates of various cellobiose concentrations and pH values. Cellobiose was used as a model sugar for subsequent experiments with lignocellulosic biomass. The culture was well adapted to cellobiose by successive subculturing at 37 °C in synthetic media (with 100:5:1 COD:N:P ratio). The experimental data of successive batch fermentations were fitted into a polynomial model for the total organic acids concentration in order to derive a predictive model that could be utilized as a tool to predict fermentation results when lignocellulosic biomass is used as a substrate. The quadratic effect of temperature was the most significant, followed by the quadratic effect of initial pH and the linear effect of cellobiose concentration. The results corroborated the validity and effectiveness of the model.
Anammox-Based Processes for Mature Leachate Treatment in SBR: A Modelling Study
Authors: Lanzetta Anna , Mattioli Davide , Di Capua Francesco , Sabia Gianpaolo , Petta Luigi , Esposito Giovanni , Andreottola Gianni , Gatti Giovanni , Merz Willy , Langone Michela
Published: August 2021

Mature landfill leachates are characterized by high levels of ammoniacal nitrogen which must be reduced for discharge in the sewer system and further treatment in municipal wastewater treatment plants. The use of anammox-based processes can allow for an efficient treatment of ammonium-rich leachates. In this work, two real scale sequencing batch reactors (SBRs), designed to initially perform partial nitritation/anammox (PN/A) and simultaneous partial nitrification and denitrification (SPND) for the treatment of ammonium-rich urban landfill leachate, were modelled using BioWin 6.0 in order to enable plant-wide modelling and optimizing. The constructed models were calibrated and validated using data from long- and short-term (one cycle) SBR operation and fit well to the main physical-chemical parameters (i.e., ammonium, nitrite and nitrate concentrations) measured during short-term (one cycle) operations. Despite the different strategies in terms of dissolved oxygen (DO) concentrations and aeration and mixing patterns applied for SBR operation, the models allowed for understanding that in both reactors the PN/A process was shown as the main contributor to nitrogen removal when the availability of organic carbon was low. Indeed, in both SBRs, the activity of nitrite oxidizing bacteria was inhibited due to high levels of free ammonia, whereas anammox bacteria were active due to the simultaneous presence of ammonium and nitrite and their ability to recover from DO inhibition. Increasing the external carbon addition, a prompt decrease of the anammox biomass was observed, with SPND becoming the main nitrogen removal mechanism. Models were also applied to estimate the production rates of nitrous oxide by aerobic ammonia oxidizing bacteria and heterotrophic denitrifiers. The models were found to be a robust tool for understanding the effects of different operating conditions (i.e, temperature, cycle phases, DO concentration, external carbon addition) on the nitrogen removal performances of the two reactors, assessing the contribution of the different bacterial groups involved.
Bailu’s Catholicism in China: Religious Inculturation, Tourist Attraction, or Secularization
Authors: Liao Xianghui
Published: August 2021

My article explores how Catholicism interacts with various forces and players in the local and political arena since it migrated into Bailu, China. My argument is based on extensive fieldwork done at two seminaries and one church there. I have shown that: (1) Catholicism encountered different secular forces and survived through effective interaction with them, (2) a market-oriented economy led to the commercialization of once-authentic religious sites for tourism and economic development, and (3) the secularization of Catholicism results in a unique paradox: Catholicism’s public influence on tourism and economic development has been increasing, while its activities and church attendance have not followed synchronously. This paradox manifests itself in two facts: though the town has benefited from Catholicism’s presence, measured by religious symbols and in numbers have been gradually reduced and even removed; and though its French influence makes this town a tourist destination, the prevailing Chinese culture has not been undermined but reinforced.
Theology of Music and Hindu Religion: From Divine Origins to Classical Songs
Authors: Beck Guy L.
Published: August 2021

As a subfield in the study of religion and music, the theology of music is generally understood in Western terms. Yet to fully encompass the rich heritage of music in world religions, the theology of music must welcome non-Western traditions. After introducing ancient Greek and Biblical narratives regarding the origins of music, including metaphysical concepts, narratives of music as Divine Gift, musical angels, and the sacred origin of the notes and scales, this article explores music in Hindu religion through the lens of theology. We find that Indian music is also ‘given by the gods’ (i.e., Brahmā, Vishnu, and Śiva), associated with ‘musical angels,’ and originally formed from metaphysical principles (i.e., OM and the concept of Nāda-Brahman). What is demonstrated here, representing a long continuity, is how these same ideas are viable in the performance of Indian classical music today. Citing examples of compositions of Dhrupad and Khayal from the standard repertoire, this article reveals how modern-day classical songs contain references to sacred sound principles and the divine origins of music, both in their lyrics and in the unfoldment of musical notes (Svaras) and melodic patterns (Rāgas).
Use of NIRS in Wild Rodents’ Research: A Review of Timid Beginnings
Authors: Čepelka Ladislav , Jánová Eva , Suchomel Josef , Heroldová Marta
Published: August 2021

The article summarizes the previous experience and results from the study of wild rodents using the NIRS method. The importance and role of rodents in ecosystems and the specifics associated with their research using the NIRS method are briefly mentioned. The results of previous partial studies are mentioned and discussed. The NIRS method proved to be a useful tool to determine the amount of a particular food ingredient in the diet from faeces or chyme and to estimate the food quality (i.e., diversity of nitrogenous substances in chyme). On this basis, other possible directions of research using the NIRS method in wild rodents are proposed. These could help to better understand both the relationship between rodents and their environment and practical management in sectors where rodents interfere with human interests, especially in agriculture and forestry.
On the Assessment GPS-Based WRFDA for InSAR Atmospheric Correction: A Case Study in Pearl River Delta Region of China
Authors: Zhang Zhenyi , Lou Yidong , Zhang Weixing , Wang Hua , Zhou Yaozong , Bai Jingna
Published: August 2021

The accuracy and applications of synthetic aperture radar interferometry (InSAR) are severely suppressed by tropospheric error. Numerical Weather Models (NWMs) and GPS-derived tropospheric delays have been widely used to correct the tropospheric error considering their complete spatial coverage or high accuracy. However, few studies focus on the fusion of both NWMs and GPS for the tropospheric error correction. In this study, we used the Weather Research and Forecasting (WRF) to obtain NWMs with a higher spatial-temporal resolution of 3 km and 20 s from both ERAI (79 km and 6 h) and ERA5 (0.25° and 1 h). After that, we utilized the WRF Data Assimilation (WRFDA) system to assimilate the GPS ZTD into these enhanced NWMs and generate merged NWMs products. The tropospheric correction effectiveness from different NWMs products was evaluated in a case in the Pearl River Delta region of China. The results showed that all the NWMs products could correct the stratified component in the interferogram but could not mitigate the turbulence well, even after improving the spatial-temporal resolution. As for the trend component, the merged NWMs products showed obvious superiority over other products. From the statistics perspective, the stdev of the interferogram decreased further over 20% by the merged NWMs products than other products when using both ERAI and ERA5, indicating the significant effectiveness of GPS ZTD assimilation.
Deformation Estimation Using Beidou GEO-Satellite-Based Reflectometry
Authors: Chen Yongqian , Yan Songhua , Gong Jianya
Published: August 2021

Deformation monitoring has been brought to the fore and extensively studied in recent years. Global Navigation Satellite System Reflectometry (GNSS-R) techniques have so far been developed in deformation estimation applications, which however, are subject to the influence of mobile satellites. Rather than compensating for the path delay variations caused by mobile satellites, adopting Beidou geostationary Earth orbit (GEO) satellites as transmitters directly eliminates the satellite-motion-induced phase error and thus provides access to stable phase information. This paper presents a novel deformation monitoring concept based on GNSS-R utilizing Beidou GEO satellites. The geometrical properties of the GEO-based bistatic GNSS radar system are explored to build a theoretical connection between deformation quantity and the echo carrier phases. A deformation retrieval algorithm is proposed based on the supporting software receiver, thus allowing echo carrier phases to be extracted and utilized in deformation retrieval. Two field validation experiments are conducted by constructing passive bistatic radars with reflecting plates and ground receiver. Utilizing the proposed algorithm, the experimental results suggested that the GEO-based GNSS reflectometry can achieve deformation estimations with an accuracy of around 1 cm when the extracted phases does not exceed one complete cycle, while better than 3 cm when considering the correct integer number of phase cycles. Consequently, based on the passive bistatic radar system, the potential of achieving continuous, low-cost deformation monitoring makes this novel technique noteworthy.
Monitoring the Prestressed Rods in the Basel Border Bridge Maintenance Project: Data Analysis during the Passage of Trucks
Authors: Schuler Harald , Meier Florian
Published: August 2021

More than 40 years ago, the expansion joints on the Basel border bridge were constructed using corbels and dapped ends. The consoles had to be reinforced as part of the renovation measures due to damage caused by chloride entry and due to the increased loads. Diagonal rods, which were prestressed, were used. Fiber-optic sensors were additionally installed to these highly stressed rods in order to measure the strains and temperatures. This now makes it possible to measure the actual strains in the strengthening of the corbel, estimate fatigue loads, and set up a warning system in case of overstressing. This article presents the design of the measurement system and the analysis of the data. Furthermore, the reference measurements that can establish the relationship between the measured strains and the loads passed over are presented.
Sex-Differentiated Attire’s Impact on Individual Action and Mate Selection
Authors: Daniels Jennifer R.
Published: August 2021

Various theories highlight the importance of using the actor/environment as the ideal unit for theoretical and experimental focus. Clothing, placed as it is as the intermediary between body and environment, is typically treated as a symbol rather than as either an integral part of either the body or the environment. When clothing is considered an extension of the body, the historical development of clothing reflects persistent differences in the physical capabilities of the human animal and operates as an instrument for solo action. In addition, it is argued that due to the ecological mechanisms connecting perception and action, differential clothing options for the sexes has led in no small part to differences in self-perception as well as the perception of others. However, when it comes to the very specific behavior of mate selection and procreation, clothing can be understood as a tether between two systemic units, offering a description of a system that allows for communication of potential social affordances and opportunities for joint action.
Social Role Narrative of Disabled Artists and Both Their Work in General and in Relation to Science and Technology
Authors: Wolbring Gregor , Jamal Al-Deen Fatima
Published: August 2021

Artists and the arts have many different roles in society. Artists also have various roles in relation to science and technology, ranging from being users of science and technology products to being educators for science and technologies, such as in museums. Artists are also involved in science and technology governance and ethics discussions. Disabled people are also artists and produce art, and disabled people in general and disabled artists are impacted by science and technology advancements. As such, disabled artists should also engage with science and technology, as well as contribute and influence science and technology governance, ethics discussions, and science and technology education with their work. We performed a scoping study of academic literature using the 70 databases of EBSCO-HOST and the database SCOPUS (includes Medline) to investigate the social role narrative of disabled artists and both their work in general and in relation to science and technology. Our findings suggest that disabled artists are mostly engaged in the context of becoming and being a disabled artist. Beyond the work itself, the identity issue of ‘being disabled’ was a focus of the coverage of being a disabled artist. The literature covered did not provide in-depth engagement with the social role of disabled artists, their work, and the barriers encountered, and best practices needed to fulfil the social roles found in the literature for non-disabled artists and the arts. Finally, the literature covered contained little content on the relationship of disabled artists and advancements of science and technology, such as in their role of using advancements of science and technologies for making art. No content at all was found that would link disabled artists and their work to the science and technology governance and ethics discussions, and no content linking disabled artists to being educators on science and technology issues, for example, in museums was found.
Offseason Body Composition Changes Detected by Dual-Energy X-ray Absorptiometry versus Multifrequency Bioelectrical Impedance Analysis in Collegiate American Football Athletes
Authors: Boykin Jake R. , Tinsley Grant M. , Harrison Christine M. , Prather Jessica , Zaragoza Javier , Tinnin Matthias , Smith Shay , Wilson Camden , Taylor Lem W.
Published: August 2021

Tracking changes in body composition may provide key information about the effectiveness of training programs for athletes. This study reports on the agreement between bioelectrical impedance analysis (BIA) and dual-energy X-ray absorptiometry (DXA) for tracking body composition changes during a seven-week offseason training program in 29 NCAA collegiate American football players. Body composition in subjects (mean ± SD; age: 19.7 ± 1.5 y; height: 179.8 ± 6.6 cm; body mass (BM: 96.1 ± 12.6 kg; DXA body fat: 20.9 ± 4.4%) was estimated using BIA (InBody 770) and DXA (Hologic Horizon) before and after the training intervention. Repeated measures ANOVA and post hoc comparisons were performed. Longitudinal agreement between methods was also examined by concordance correlation coefficient (CCC) and Bland–Altman analysis alongside linear regression to identify bias. Significant method by time interactions were observed for BM (DXA: 1.1 ± 2.4 kg; BIA: 1.4 ± 2.5 kg; p < 0.03), arms fat-free mass (FFM) (DXA: 0.4 ± 0.5 kg; BIA: 0.2 ± 0.4 kg; p < 0.03), and legs FFM (DXA: 0.6 ± 1.1 kg; BIA: 0.1 ± 0.6 kg; p < 0.01). Post hoc comparisons indicated that DXA—but not BIA—detected increases in FFM of the arms and legs. Time main effects, but no method by time interactions, were observed for total FFM (DXA: 1.6 ± 1.9 kg; BIA: 1.2 ± 2.1 kg; p = 0.004) and trunk FFM (DXA: 0.7 ± 1.3 kg; BIA: 0.5 ± 1.0 kg; p = 0.02). Changes in total BM (CCC = 0.96), FFM (CCC = 0.49), and fat mass (CCC = 0.50) were significantly correlated between BIA and DXA. DXA and BIA may similarly track increases in whole-body FFM in American collegiate football players; however, BIA may possess less sensitivity in detecting segmental FFM increases, particularly in the appendages.
Sustainable Investment: Consequences for Psychological Well-Being
Authors: Gärling Tommy , Jansson Magnus
Published: August 2021

This paper sets the stage for research on sustainable investment (SI) related to psychological well-being (PWB). It recognizes the threat of current global consumption levels to exceed the planetary boundaries and asks what roles financial markets may play in reducing these threats without compromising PWB. SI integrates environmental (E), social (S), and governance (G) factors alongside financial factors in investments in company shares and bonds as well as through active engagement in companies. Barriers to ESG integration include lower short-term financial performance, higher financial risks, and insufficient ESG screening by investors. A brief review of PWB shows that reliable and valid measurement methods have been developed, that the resulting measures complement economic and social national welfare indicators, and that health, sufficient material welfare, income equality, and non-material consumption are important determinants of PWB. The challenge is to globally reduce private material consumption levels in affluent countries. It is suggested that one role SI may play is in investing or actively engaging in companies that efficiently meet an increasing consumer demand of non-material consumption. Future research should address this role of SI.
Multi-Stakeholder Platform in Water Resources Management: A Critical Analysis of Stakeholders’ Participation for Sustainable Water Resources
Authors: Sigalla Onesmo Z. , Tumbo Madaka , Joseph Jane
Published: August 2021

Multi-stakeholder platforms (MSPs) have gained momentum in addressing contentious and cross-sectoral aspects of natural resources management. They have helped to enhance cross-learning and the inclusion of marginalized groups. Tanzania’s water resources management sub-sector has championed these platforms as a means of breaking silos around planning, coordination, and resource mobilization. However, it is not uncommon to experience the occasional dominance of some influential sectors or groups due to their resources contribution to the process, contemporary influence, or statutory authority. Between 2013 and 2020, Tanzania has pioneered the establishment of MSPs at a national level and across the river and lake basins. This paper examines the representation of stakeholder groups in these platforms. Additionally, it establishes the baseline information that contributes to unlocking the current project-based platform design characterized by inherent limitations to potential changes in stakeholders’ attitudes and actions. The research analyzed stakeholder’s views, their representation, and the local and international literature to formulate opinions. Findings indicated that gender equality had not been adhered to despite being in the guidelines for establishing MSPs. The balance of public, private, and civil society organizations (CSOs) is acutely dominated by the public sector organizations, especially water-related ones. Finally, participation on the decision-making level is minimal, causing unsustainable platforms unless development partners continue to support operational costs.
Does the Reflection of Foci of Commitment in Job Performance Weaken as Generations Get Younger? A Comparison between Gen X and Gen Y Employees
Authors: Çelik Ahmet Alkan , Kılıç Mert , Altındağ Erkut , Öngel Volkan , Günsel Ayşe
Published: August 2021

Today’s organizations increasingly recognize the fact that employees and employee performance are essential intangible assets that should be effectively managed. Affective commitment (AC) is a widely recognized antecedent of sustainable job performance. However, achieving AC has become a great challenge in general and has been especially difficult since the beginning of the pandemic because almost all companies asked their employees to stay at home and work remotely in an isolated manner. Today, many different generations work side by side, contrary to the past, when generational mixing was very rare. Many differences exist among these employee generations, which determine their feelings towards authority and organization. Accordingly, this paper aims to clarify generational differences in the interrelationships among AC and sustainable job performance between Gen X and Gen Y employees. As remote working structure limits the interactions that employees have with their supervisor, fellow employees, and the organization, we decided to use the foci of commitment: affective commitment to the organization, affective commitment to the supervisor, and affective commitment to coworkers. Based on data from 416 post-graduates of Beykent University and using the PLS-SEM technique, we find that commitment to the supervisor and commitment to the organization are positively associated with job performance. Moreover, the findings reveal that the impact of the relationship between commitment to the supervisor and job performance is weaker for Gen Y than for Gen X.
Wildlife Conservation through Economically Responsible Ecotourist: The Mediator Roles of Attitude between Anticipated Emotion and Intention to Stay in Local Homestays
Authors: Ibrahim Hayati , Mariapan Manohar , Lin Evelyn Lim Ai , Bidin Sheena
Published: August 2021

If responsible ecotourists stay in a local homestay, this will benefit local people economically and lead to improved wildlife conservation. This study aims to examine the mediator roles of attitudes between anticipated emotion and intention. It was conducted in Penang National Park, Malaysia, and a stratified sampling method was used for collecting the data. In all, 320 sets of questionnaires were analysed using the SPSS Amos 24.0 Statistical Software Package to test the Structural Equation Modelling. The findings show that economically responsible ecotourist attitudes to staying in local homestays for wildlife conservation partially mediate the relationship between anticipated emotion and intention to stay in a local homestay for wildlife conservation. This study suggests that players in the ecotourism industry should incorporate emotional elements in their marketing strategies to promote local homestays to responsible ecotourists, which would benefit local economies.