bluuebunny/crossref_metadata_2025 huggingface dataset:
HİZMET İÇİ EĞİTİMİN TÜKENMİŞLİK SENDROMU ÜZERİNDEKİ ETKİSİNİN CİNSİYET BAĞLAMINDA İNCELENMESİ
Authors: MUM Sergen , BOZYİĞİT Sezen
Published: June 2022

Teknolojik gelişmeler ve küreselleşme ile ticari sınırların ortadan kalkması lojistik sektörüne duyulan ihtiyacı artırmıştır. Lojistik sektörüne duyulan ihtiyaç ve lojistik sektörünün dinamik yapısı iş yükünün artmasına ve böylelikle de lojistik çalışanlarının stres seviyesinin yükselmesine neden olmuştur. Stres seviyesinin yükselmesi ile çalışanların psikolojik ve fiziksel olarak kendilerini kötü hissetmeleri tükenmişlik sendromuna yakalanma olasılığını artırmaktadır. İşletmeler iş yükü karşısında oluşan stresi azaltmak, değişimler karşısında çalışanların hazırlıklı olmalarını sağlamak, niteliklerini geliştirmek ve rekabet ortamında üstünlük sağlamak amacıyla çalışanlarına hizmet içi eğitimler vermektedir. Bu araştırmanın amacı da lojistik işletmelerinde çalışanların almış oldukları hizmet içi eğitimlerin tükenmişlik sendromu üzerindeki etkisini cinsiyet bağlamında incelemektir. Araştırmanın örneklemini Türkiye’de faaliyet gösteren lojistik işletmelerinin hizmet içi eğitimi almış 336 çalışanı oluşturmaktadır. Araştırmada veriler online anket tekniği ile toplanmış ve Yapısal Eşitlik Modeli kullanılarak analiz edilmiştir. Araştırma sonucunda lojistik işletmelerinde verilen oryantasyon eğitiminin kadınlarda tükenmişlik sendromunun alt boyutlarından duygusal tükenmişliği, duyarsızlaşmayı ve kişisel başarısızlığı, erkeklerde ise sadece kişisel başarısızlığı olumsuz etkilediği tespit edilmiştir. Ayrıca rotasyon eğitiminin erkeklerde ve kadınlarda kişisel başarısızlığı, ayrıca erkeklerde duygusal tükenmişliği olumsuz etkilediği gözlemlenmiştir.
MUHASEBE MESLEK MENSUPLARININ MESLEK ETİĞİ HAKKINDAKİ ALGI VE TUTUMLARININ İNCELENMESİ: TRB1 BÖLGESİNDE BİR ARAŞTIRMA
Authors: KAYA Hamza , DURMUŞ Ahmet Fethi
Published: June 2022

Özet: Muhasebe meslek mensuplarının muhasebe meslek etiğine dikkat etmeyip sundukları yanlış ve yanıltıcı muhasebe bilgileri sonucunda ortaya çıkan muhasebe skandallarının ilgili tarafları ve dolayısıyla tüm toplumu olumsuz manada etkilediği görülmüştür. Bu nedenle yapılan çalışmalarda muhasebe mesleğinde teknik bilgi ve uzmanlığın tek başına yeterli olmadığı, ayrıca konunun etik boyutunun teknik yönünden daha önemli olduğu anlaşılmıştır. Bu çalışmada muhasebe meslek mensuplarının meslek etiği hakkındaki algı ve tutumları incelemiştir. Bunların yanında etik dışı davranışları caydıran faktörleri ve temel etik ilkelerin önem derecesine göre sıralamaları çalışmanın diğer bir amacını oluşturmuştur. Böylece TRB1 Bölgesi’nde faaliyet gösteren bağımsız muhasebe meslek mensuplarıyla yüz yüze anket uygulamalı bir araştırma yapılmıştır. Yapılan araştırma sonuçlarına göre; i) etik ilkelerin sıralanmasında “Dürüstlük” ilkesi ilk sırada yerini alarak diğer ilkelere göre daha önemli bulunmuş, ii) meslek etiği algılarında X̄=3,68 gibi bir ortalama bulunmuş, iii) mesleki etik ilke ve kurallara uymalarında etkili olan faktörlerin başında “mesleki eğitim ve deneyim”in geldiği görülmüştür. Ayrıca meslek mensuplarının meslek etiğine yönelik algılarında temel etik ilkelerin bazıları ile cinsiyet, etik eğitimi, eğitim düzeyi, mükellef sayısı mesleğin geleceği ve personel sayısı değişkenleri arasında anlamlı bir farklılığın olduğu; mesleki unvan, yaş, mesleki tecrübe, gelir düzeyi ve iller değişkenleri arasında ise anlamlı bir farklılığın olmadığı tespit edilmiştir.
GASTRO-TURİSTLERİN YERELLİK VE YİYECEK KİŞİLİK ÖZELLİKLERİNİN YEREL YİYECEK SATIN ALMA NİYETİNE ETKİSİ: GAZİANTEP İLİ ÖRNEĞİ
Authors: KOÇ APUHAN Ayşe , KEMENT Üzeyir
Published: June 2022

Bu araştırmanın amacı Gaziantep ilini ziyaret eden turistlerin yerellik tercihlerinin ve yiyecek kişilik özelliklerinin yerel yiyecek tutumuna ve yerel yiyecek satın alma niyetine etkisini anlamaktır. Araştırmada yerellik tercihi, yiyecek kişilik özellikleri, yerel yiyecek tutumu ve yerel yiyecek satın alma niyeti ölçekleri kullanılmıştır. Araştırmanın birincil verilerini Gaziantep ilini ziyaret eden 412 turiste kolayda örneklem metodu kullanılarak uygulanan anketler oluşturmaktadır. Araştırma verileri SPSS istatistik programında kodlandıktan sonra Smart PLS istatistik programında yapısal eşitlik modeliyle analiz edilmiştir. Araştırma modelinde kullanılan ölçeklerden yerellik tercihi alt faktörü toplumsallaştırmanın formatif ve diğer ölçeklerin de reflektif özellik gösterdiği tespit edilmiştir. Bu bağlamda ölçüm yöntemi olarak kısmi en küçük kareler yöntemi kullanılmıştır. Araştırma sonuçları incelendiğinde, dikkat çekme tercihinin yerel yiyecek tutumunu pozitif yönde anlamlı olarak etkilemediği, karşı çıkma tercihi ve toplumsallaştırma tercihinin yerel yiyecek tutumunu pozitif yönde anlamlı olarak etkilediği sonucuna ulaşılmıştır. Ayrıca yiyecek neofilisi kişilik özelliğinin, yerel yiyecek tutumunu pozitif yönde anlamlı olarak etkilediği ve yiyecek neofobisi kişilik özelliğinin, yerel yiyecek tutumunu negatif yönde anlamlı olarak etkilemediği tespit edilmiştir. Son olarak yerel yiyecek tutumunun, yerel yiyecek satın alma niyetini pozitif yönde anlamlı olarak etkilediği sonucu bulunmuştur.
Humanitarismo como deuda: Alemania y su memoria traumática
Authors: Martín Martín Juan Manuel , Domínguez Macías Leopoldo
Published: June 2022

La decisión de Angela Merkel de abrir sin reservas las fronteras de su país en 2015 a cientos de miles de refugiados representa uno de los acontecimientos más relevantes de la historia de Alemania en el siglo xxi. Tanto la determinación de la canciller como la actitud manifestada por la mayoría de los ciudadanos han de ser interpretadas en el contexto de una historia caracterizada tanto por el sufrimiento infligido por Alemania como por el sufrimiento propio derivado de los conflictos bélicos en los que se vieron inmersos. A este respecto, el humanitarismoalemán posterior a 1990 se debe en parte a una deudacon el pasado: bien como restitución del daño causado, bien como recordatorio del dolor sufrido. Ámbitos tan diversos como el discurso político o la literatura contribuyeron durante décadas a conformar una memoria cultural que prestaba especial atención al traumático siglo xx y a las responsabilidades nacionales que aún no habían prescrito.
Öğretmenlerin Kişisel Hesap Verebilirliği Ölçeği Geçerlik ve Güvenirlik Çalışması
Authors: ÇETİN Münevver , BOZKURT Derya Ülhatun
Published: June 2022

Araştırmanın amacı, öğretmenler için kişisel hesap verebilirlik ölçeğinin geliştirilmesidir. Araştırma tarama modeli şeklindedir. Açımlayıcı faktör analizi için 571 katılımcı, doğrulayıcı faktör analizi için ise 250 katılımcı ile çalışılmıştır. Araştırmanın evrenini, İstanbul ili; Bahçelievler, Bakırköy, Bayrampaşa, Fatih, Küçükçekmece ve Zeytinburnu ilçelerindeki devlet okullarında ve özel okullarda görevli olan öğretmenler oluşturmaktadır. Araştırmada tesadüfi olmayan örnekleme yöntemlerinden kolay ulaşılabilir örnekleme yöntemi kullanılmıştır. Yapılan faktör analizi sonuçlarına göre ölçeğin KMO değeri 1.361, Bartlett testi değeri 6781.330 (p<0.05)’dir. Geliştirilen ölçeğin toplam varyans değeri (%55.699) ideal kabul edilmekte ve ölçek; içsel, dışsal, kişisel fayda ve kontrol olmak üzere dört boyuttan ve 25 maddeden oluşmaktadır. Ölçeğin Cronbach Alpha kat sayısı .919 ‘dur. Çalışmanın ikinci aşamasında, elde edilen faktör yapısını doğrulamak amacıyla doğrulayıcı faktör analizi uygulanmıştır. Yapılan analiz sonucunda elde edilen uyum istatistiklerinin ölçeğin daha önce belirlenen faktör yapısıyla normal düzeyde uyumlu (χ2/sd 1.361) olduğu tespit edilmiştir. Yapılan analizler sonucunda geliştirilen ölçeğin öğretmenlerin kişisel hesap verebilirliğini ölçebilecek geçerlik ve güvenirlikte olduğu saptanmıştır.
Relationship between PD-L1 expression and prognostic factors in high-risk cutaneous squamous and basal cell carcinoma
Authors: Yülek Özden , Batur Şebnem , Özcan Kerem , Yol Cansu , Aydın Ülgen Övgü
Published: June 2022

This study aimed to investigate the programmed cell death-ligand 1 (PD-L1) expression in cutaneous squamous cell carcinoma (cSCC) and basal cell carcinoma (BCC) and its relationship with prognostic factors in tumors that are not in the head and neck region and are therefore relatively less exposed to the sun. This retrospective cross-sectional study included 25 invasive cSCC and 42 BCC cases with a diameter ≥ 2 cm located outside the head and neck region from 2010 to 2018. The biopsy samples were examined based on the membranous PD-L1 (22C3 clone) staining. Staining results were scored as follows: 0, no staining (negative); 1, < 10% PD-L1 positivity of tumor cells; and 2, ≥ 10% PD-L1 positivity of tumor cells. PD-L1 positivity was not seen in any BCC cases, whereas 11 (44%) of cSCC cases were PD-L1 positive. No significant relationship was observed between PD-L1 expression and prognostic parameters, including tumor diameter, tumor depth, and lymphovascular or perineural invasion in the cSCC group. PD-L1 expression was not associated with prognostic factors in the early stages of BCC and SCC located outside the head and neck region. Therefore, investigating the PD-L1 expression seems to be more relevant in patients with advanced-stage disease.
Trusted artificial intelligence: Strengthening digital protection
Authors: Avdoshin Sergey , Pesotskaya Elena
Published: June 2022

This article is devoted to aspects associated with the up-coming need for mass implementation of neural networks in the modern society. On the one hand, the latter will fully expand the capabilities of state institutions and society delegated to perform numerous tasks with higher efficiency. However, a significant threat to democratic institutions obliges society to set out the concept of reliable artificial intelligence (AI). The authors explore a new concept of a trusted AI necessary for the scientific and international community to counter improper future digital penetration. Explaining to what extent digital transformation is mandatory, the authors emphasize the numerous dangers associated with the applications of artificial intelligence. The purpose of the article is to study the potential hazards of neural networks’ abuse by the authorities and the resistance to them with reliance on the trusted AI. Studying various aspects of digital transformation and the use of artificial intelligence technologies, the authors formalize the dangers associated with the emergence and propose an approach to the use of digital protection technologies that can be trusted.
Supplementation of Thymoquinone and Carob Together in the Experimental Rat Asthma Model: Oxidative Effect on the Liver Tissue
Authors: AKYAZI Özge , CEVHER Şule Coşkun
Published: June 2022

Asthma, an important public health problem, is a common, potentially serious, medical condition in children, adults and pregnant women. The aim of this study is to investigate the effects of the combined use of thymoquinone and carob on liver tissue oxidative events, following the experimental asthma model. 18 male albino wistar rats were divided into 3 groups as: the control group, the experimental asthma group and treated group (A+TQ+C). In the asthmatic groups, ovalbumin and alum were given intraperitoneally on the 0 and 14th days, and sensitized by inhalation on the 21st, 22nd and 23rd days. In the next 5 days, thymoquinone and carob were given to the group to be treated by intragastric gavage method. In all experimental groups, glutathione (GSH), ascorbic acid (AA), malondialdehyde (MDA) and nitric oxide (NOx) levels were measured spectrophotometrically to evaluate the oxidant-antioxidant status in the liver tissue of rats. While liver tissue GSH and AA levels increased, NOx levels were found to decrease following thymoquinone and carob administration in the treated group (A+TQ+C) when compared other groups (Control and Asthma). However, MDA levels, which are the indicator of lipid peroxidation, were found to be statistically significantly increased in the treated group (A+TQ+C) (p
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Authors: A H
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Cloning gene of interest into attb plasmid for PhiC31 integration v1
Authors: Tomic Goran
Published: June 2022

This protocol describes a simple cloning procedure to insert a gene of interest (GOI) into an attb plasmid to use in combination with PhiC31 integration to generate low-copy integrants.
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Authors: H H
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Authors: not provided dhjsfcjo
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Authors: not provided sharoncrowl
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Natural killer cell depletion in vivo (mouse) v1
Authors: Tomic Goran
Published: June 2022

This protocol describes a validated procedure for antibody depletion of natural killer cells in mice (C57Bl/6J and 129SvEv strains), combined with the injection of cancer cells i.v. It is based on combining a few references and testing the optimal antibody concentration and frequency of injection to achieve good level of depletion, minimise animal injection frequency, and reagent consumption.
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Authors: not provided kendriclamer
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Authors: not provided jivevi
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MOCK INTERVIEW: SELF-PERCEIVED COMPETENCE AND ACTUAL PERFORMANCE AMONG ESL UNDERGRADUATES
Authors: Mohamad Utama Asniza
Published: June 2022

The purpose of this paper is to investigate self-perceived competence and actual performance among ESL undergraduates in Malaysia. This study investigates the differences between students’ self-perceived competence and actual performance in mock interviews. The study was conducted in Kulliyyah of Islamic Revealed Knowledge and Human Sciences at International Islamic University Malaysia (IIUM). The survey was distributed to 40 ESL undergraduates who were attending Language for Occupational Purposes (LE 4500) course. A descriptive quantitative method is used to examine the two variables involved in this study. The result revealed that students perform better than they think they are. The results of this study show that they underestimate their capability to do well in mock interview. This study helps give instructors a better understanding about the student perspective. It could be implied students’ lack of confidence drives them to work harder in order to do well in the mock interviews.
Efficient and Secure ECDSA Algorithm and its Applications: A Survey
Authors: Al-Zubaidie Mishall , Zhang Zhongwei , Zhang Ji
Published: June 2022

Public-key cryptography algorithms, especially elliptic curve cryptography (ECC)and elliptic curve digital signature algorithm (ECDSA) have been attracting attention frommany researchers in different institutions because these algorithms provide security andhigh performance when being used in many areas such as electronic-healthcare, electronicbanking,electronic-commerce, electronic-vehicular, and electronic-governance. These algorithmsheighten security against various attacks and the same time improve performanceto obtain efficiencies (time, memory, reduced computation complexity, and energy saving)in an environment of constrained source and large systems. This paper presents detailedand a comprehensive survey of an update of the ECDSA algorithm in terms of performance,security, and applications.
Tıbbi Önemi Olan Hyoscyamus niger L.: Fenolik Madde İçeriği ve in vitro Antiproliferatif Aktiviteleri
Authors: ALAN Yusuf , KURŞAT Murat
Published: June 2022

Tıbbi önemi olan bitkiler, zengin bileşenleri nedeniyle kanser de dahil çeşitli hastalıkların tedavisinde en önemli ilaç kaynaklarından birini temsil etmektedirler. Bu çalışmanın amacı, Hyoscyamus niger bitkisinin toprak üstü kısımlarının metanol (HNM) ve su (HNS) ekstraktlarının 17 farklı fenolik madde içeriğini araştırmak, in vitro antiproliferatif aktivitesini değerlendirmektir. Bu amaçla ekstraktların 17 farklı fenolik madde içeriği HPLC ile belirlendi. Antiproliferatif aktivite ise, karaçiğer kanseri hücre hattı (Hep G2), osteosarkoma hücre hattı (U-2 OS) ve sağlıklı fare fibroblast hücre (L-929) hücre hatlarına karşı MTT testi ile tayin edildi. Ekstraktlarda en fazla miktarda askorbik asit belirlendi. HNM ekstraktı içerik yönünden HNS ekstraktından daha zengindi. Antiproliferatif aktivite sonuçlarına göre en güçlü etkiyi HNM ekstraktı, özellikle Hep G2’ye karşı gösterdi. Genel olarak değerlendirildiğinde HNM ekstraktının fenolik madde içeriği ve antiproliferatif aktivite bakımından daha iyi olduğu belirlendi. Bitki ekstraktlarının aktif bileşenlerinin izole edilerek daha fazla in vivo ve in vitro çalışmaların yapılması önem arz etmektedir.
Utilização do Oléo de Girassol Ozonizado no Tratamento Tópico de Ferida por Farmacodermia em Cão: Relato de Caso
Authors: Cabral de Souza Rafaela , Conceição Melhor Ariane , Caroline de Andrade Oliveira Marilia , Pinto dos Santos Veloso Mateus , Gonçalves Dias Rafaela Andréa , Oliveira de Araújo Barreto Cinthia , Carneiro de Araújo Machado Marília
Published: June 2022

A farmacodermia é uma reação de hipersensibilidade observada em pele, mucosas e anexos, após utilização de algum fármaco. É uma afecção de pouca ocorrência em cães, geralmente observada após a administração de medicamentos por qualquer via. Em casos de apresentações clínicas mais graves, deve ser realizado o tratamento de suporte, por meio da administração de eletrólitos, antibioticoterapia, medicações para controle da dor e aplicação de soluções antissépticas nas lesões. O gás ozônio (O3), por sua vez, é um dos agentes amplamente utilizados para tratamento de feridas, o qual atua como agente terapêutico no tratamento de diversas doenças. É considerado economicamente acessível, de baixo risco, que pode ser aplicado como método complementar, aditivo ou restaurativo. O presente relato descreveu a utilização do óleo de girassol ozonizado como tratamento tópico único de ferida ocasionada por farmacodermia em cadela, após uso de cefalexina. O tratamento instituído foi eficaz e com melhora satisfatória dos sinais clínicos apresentados. Houve progressiva redução da extensão e profundidade das lesões, com granulação tecidual e reepitelização, além da ausência dos focos infecionados.
 
Palavras-chave: Cicatrização. Ozonioterapia. Toxidermia.
 
Abstract
Pharmacoderma is a hypersensitivity reaction observed in the skin, mucous membranes and attachments, after the use of a drug. It is a condition of little occurrence in dogs, usually observed after the administration of medications by any route. In cases of more severe clinical
presentations, supportive treatment should be performed, through the administration of electrolytes, antibiotic therapy, medications for pain control and application of antiseptic solutions to the lesions. Ozone gas (O3), in turn, is one of the agents widely used for wound care. O3 acts as a therapeutic agent in the treatment of various diseases. It is considered economically accessible, of low risk, which can be applied as a complementary, additive or restorative method. The present report describes the use of ozonated sunflower oil as a single topical treatment of a wound caused by pharmacoderma in a dog, after the use of cephalexin. The treatment instituted was effective and with satisfactory improvement of the clinical signs presented. Progressive reduction in the extension and depth of the solutions, with tissue granulation and re-epithelialization, in addition to the absence of infected.
 
Keywords: Healing. Ozone therapy. Toxidermy.
Toxoplasmose Ovina: Revisão de Literatura
Authors: Barros Magalhães de Lima Raisa , Lima Tomé Melo Andréia
Published: June 2022

A ovinocultura é desenvolvida em diversas regiões do país e do mundo, formada por animais com capacidade de adaptação a condições ambientais adversas, e neste cenário, o Brasil se destaca por ser considerado o primeiro produtor de ovinos do Continente Americano, com um rebanho de aproximadamente 18 milhões de cabeças. Nesse contexto, diversas enfermidades infecciosas têm provocado grandes prejuízos, incluindo aquela causada pelo protozoário Toxoplasma gondii, que resulta em problemas reprodutivos e perdas econômicas na ovinocultura. O T. gondii é o agente etiológico da toxoplasmose, uma importante zoonose, com distribuição cosmopolita e de grande interesse em saúde pública. Trata-se de um agente que pode provocar sérios danos aos fetos, pela transmissão vertical tanto em humanos quanto nos animais podendo causar abortamento ou infecção congênita em seus hospedeiros intermediários, tendo os felídeos como os únicos hospedeiros definitivos. Este artigo foi elaborado por meio de pesquisa bibliográfica, com o objetivo de abordar acerca da toxoplasmose ovina. Diversos trabalhos têm demonstrado a detecção do parasito em carnes destinadas ao abate, sendo muito relevante em âmbito de saúde pública, pois é uma fonte de infecção para os humanos caso não seja realizado o cozimento destes alimentos de maneira eficiente. Por isso, é essencial que sejam estabelecidas medidas sanitárias nas criações de ovinos como forma de prevenir a propagação da doença.
 
Palavras-chave: Protozoário. Ovinocultura. Abortamento.
 
Abstract
Sheep farming is developed in several regions of the country and the world, made up of animals with the ability to adapt to adverse environmental conditions, and in this scenario, Brazil stands out for being considered the first sheep producer on the American continent, with a herd of approximately 18 million heads. In this context, several infectious diseases have caused great damage, including that caused by the protozoan Toxoplasma gondii, which results in reproductive problems and significant economic losses in sheep farming. T. gondii is the etiologic agent of toxoplasmosis, an important zoonosis, with cosmopolitan distribution and great interest in public health. It is an agent that can cause serious damage to fetuses, due to vertical transmission in both humans and animals, causing abortion or congenital infection in their intermediate hosts, and the felids are the only definitive hosts. This article was elaborated through bibliographical research, with the objective of approaching the one about sheep toxoplasmosis. Several studies have demonstrated the parasite detection in meat intended for slaughter, which is very relevant in terms of public health, as it is a source of infection for humans if these foods are not cooked efficiently. Therefore, it is essential to establish sanitary measures in sheep farming as a way to prevent the spread of the disease.
 
Keywords: Protozoa. Sheep farming. Abortion.
Anterior capsule sparing parsplana lensectomy in cataract with severely compromised corneal endothelium
Authors: Ganekal Sunil , Ganekal Varun
Published: June 2022

To evaluate the results of parsplana lensectomy in the management of cataract with severely compromised or abnormal corneal endothelium.

Retrospective interventional case study comprised 22 patients (9 women, 13 men; 22 eyes) with severely abnormal corneal endothelium ut still had transparent cornea. Of which 14 had history of penetrating keratoplasty, 6 had history of trabeculectomy and 2 were diagnosed with Fuch’s endothelial dystrophy. Postoperative est corrected visual acuity (BCVA), mean density of corneal endothelial cell and other complications were analyzed.

Mean follow-up period was 17.2 months (ranging from 6 to 31 months). Postoperative BCVA were found to be 6/60 or below in 2 patients, 6/60-6/18 in 7 patients and 6/18-6/12 in 7 patients and 6/12 or better in 6 patients. BCVA improved in all patients after surgery, except in one patient with Fuch’s endothelial dystrophy BCVA turned worse again about five months after surgery and eventually patient developed bullous keratopathy. The mean density of corneal endothelial cells was 1018± 84/ mm (range 844/ mm to 1176/ mm) before operation and 981±93/ mm (range 853 to 1211/ mm) after operation. No significant difference in the density of corneal endothelial cells was found among the patients before and after operation (P=0.43).

Pars plana lensectomy is able to decrease surgically-induced corneal endothelial damage and is safe in the management of cataract with severely compromised corneal endothelium.
Detection of macular findings in highly myopic eyes with OCT and to correlate it to various visual parameters
Authors: Gumber Bhanvi , Neiniwal Sanjeev K , Harsolia Ramswaroop
Published: June 2022

: High myopia is when axial length is more than >26 mm and refractive error of atleast 6.00 diopters (D). The definition of pathologic myopia in early studies was not consistent. It revolved around a combination of refractive error and axial length, which simply suggests high myopia.

To study the pathological findings in subjects with high axial myopia and their relationship with other visual parameters.

In this crosssectional analytical study, 200 eyes from 100 patients were studied. Fundus was evaluated with indirect ophthalmoscope. After pupillary dilatation, multiple OCT scans were performed across the macula area centering the fovea with the help of SD-OCT

SD OCT revealed that 46% had normal appearance. Among pathological findings, most common was CNV (10%). Other findings were lamellar macular hole (7%), full thickness macu lar hole (7%), retinal detachment (3%), epiretinal membrane (3%), traction maculopathy (4%), PVD (8%), dome shaped macula (8%)and posterior staphyloma (4%).

Fifty four percent eyes had one or more fundus changes observed by bio-microscopy. Most common findings were lattice degeneration (33.33%) and WWP & WWOP (25%). Other findings were posterior staphyloma (7.41%), retinal detachment (5.51%), Chorioretinal degeneration (11.11%), macular hole (8.3%), PVD (3.70%), Retinal hole (0.92%), maculopathy (0.97%) and CNV (3.70%).

: OCT can be done in a healthy high myopic population and in symptomatic myopic population who complains of worsening of visual function to look for epiretinal and/or vitreoretinal traction and related macular damage.
Clinico-epidemiological profile of patients presenting to tertiary eye care hospital in south India for blindness certificate – A prospective observational study
Authors: Kumar Niranjan Karthik Senthil , Geetha P  , Santha G Sai , Gnanaoli M
Published: June 2022

To evaluate and analyze the causes of visual impairment, handicap, and blindness in a tertiary eye hospital among patients applying blindness certificates in Chennai.  

Applications for blindness certificates were analyzed over two years (2019-2021). The main cause of blindness, visual handicap, and visual impairment in these applications was ascertained by age group and etiology. Visual impairment disability percentages and definitions proposed by the Government of India [category 0-4, 20-100%] were used to categorize and give a percentage to all applicants. Results were compared with data from studies on blindness certificates and population-based studies.  

A total of 118 applications were reviewed. The mean age was 23.5±7.9 (range 12 to 65 years). The most common causes of blindness were retinitis pigmentosa and optic atrophy. In the age group 0-15 years, phthisis bulbi followed by microphthalmos were found to be the most common cause of blindness. Among the 15-30 years age group, macular pathology was the most common cause of visual blindness. Between 30-40 years of age group Retinitis pigmentosa is most common. Above 40-60 years of age, optic atrophy and glaucoma were the most common cause of blindness. 

Data from applications for blindness certificates provide valuable information regarding different causes of visual blindness provide an insight into the overall trends in disease profile and service delivery.
Case series of Euthyroid Graves’ Ophthalmopathy in patients seronegative for TSH receptor autoantibody (TRAb) & developed Hyperthyroidism in follow-up visits
Authors: Saha Avijit , Chowdhury Somnath
Published: June 2022

We reported cases of Graves’ ophthalmopathy who presented solely with symptoms of the eyes and normal thyroid function tests, negative TSH receptor autoantibody (TRAb). These cases were referred to our hospital for unilateral or bilateral eye swelling with painful eye movements, with or without double vision, without any signs or symptoms of hyper- or hypothyroidism. Serum thyroid function tests and 99mTc uptake studies were within the normal range. Anti-thyroid autoantibodies (TRAb) were negative in all the cases. Since orbital CT scan and MRI gave typical results compatible with Graves’ ophthalmopathy and after exclusion of other possibilities, these patients were treated with corticosteroid pulse therapy and orbital radiation therapy, leading to a partial improvement of the symptoms. We followed up those cases with serial thyroid profile testing and TRAb estimation and they were subsequently developed clinical & biochemical hyperthyroidism within the next 18 months follow-up. At that time, they also became TRAb positive. These cases give us insight into the potential pathophysiologic mechanism underlying Graves’ ophthalmopathy and cast light upon the difficulties of establishing the diagnosis in biochemically euthyroid & thyroid autoantibody negative cases. Clinicians should be aware of the variable temporal relationship between the clinical expression of thyroid dysfunction and orbital disease in the natural course of Graves’ disease.
A case report of bilateral, symmetrical intermediate uveitis in a post COVID 19 Indian patient
Authors: Barne S Swati , Devika S Joshi , Nikhil N Beke
Published: June 2022

Many ocular manifestations such as conjunctival congestion and central retinal artery occlusion were noticed in covid and post-covid patients, ut a case of bilateral symmetrical intermediate uveitis in post covid patient has been very rarely reported till date. A 62-year old hypertensive female who suffered from COVID 19 illness complained of diminution of vision for both distance and near along with complaints of floaters in both the eyes three months after covid recovery. After carrying out detailed systemic and ophthalmic evaluation, she was diagnosed with bilateral symmetrical intermediate uveitis which responded very well to tapering doses of oral and topical steroids. Early diagnosis and intervention is very essential to treat a y ocular symptoms in post-covid patients to regain normal visual acuity.

This is a very rare case of bilateral symmetrical intermediate uveitis in post-covid Indian patient which is responsive systemic and topical steroids.
Libraries @ national education policy (NEP 2020) in India
Authors: Asif Mohammad , Singh K. K.
Published: June 2022

Present article highlights Libraries and their importance in our education system. The New Education Policy 2020 advocates school, college and higher education equally. This article mainly focuses on the key highlights of NEP 2020 including Library features. National Educational Policy 2020 (NEP) intended to focus on Library as essential service in the context of the Schools / Colleges / University systems in India. The services provided by the Libraries presents a set of advantages to play most significant role in study, research, education and skill development.
Resolviendo el problema de valores propios complementarios mediante un algoritmo cuasi-Newton
Authors: Arenas Favian , Arias Carlos , Pérez Rosana
Published: June 2022

En este artículo consideramos el problema de valores propios complementarios, de gran interés para muchos investigadores por sus numerosas aplicaciones en Ingeniería y Física, y abordamos su solución como un problema de complementariedad no lineal usando un método cuasi-Newton, un tipo de método que, hasta donde conocemos, no ha sido utilizado para dicho fin. Verificamos que el problema satisface ciertas hipótesis que permiten utilizar un algoritmo global cuasi-Newton y realizamos pruebas numéricas que muestran la eficacia del algoritmo utilizado y lo hacen una buena alternativa de solución para problemas de valores propios complementarios.
Variación estacional de abejas euglosinas (Apidae: Euglossini) en el norte de la Orinoquia colombiana
Authors: Pérez-Buitrago Néstor , Mojica-Candela Laura Johana , Agudelo-Martínez Juan Carlos
Published: June 2022

Las abejas euglosinas son importantes polinizadores de múltiples especies de plantas neotropicales, pero en muchas localidades de Colombia existe poca información sobre su presencia. El objetivo de este estudio fue documentar el cambio en la riqueza y abundancia de especies de las abejas de las orquídeas (Apinae: Euglossini) durante las temporadas seca y lluviosa en tres ambientes (bosque de galería, sabana inundable, y un sendero con vegetación secundaria) del departamento de Arauca, Colombia. Los especímenes se recolectaron por captura directa usando cebos libres y la instalación de 32 trampas de botella y cuatro tipos de cebo. La intensidad diaria del muestreo fue de siete horas (7:00-14:00) durante 10 días consecutivos en cada temporada climática. Se recolectaron 367 especímenes pertenecientes a tres géneros y 17 especies que representaron entre el 81,1 y el 91,9 % de las especies esperadas en la zona de estudio. La sabana inundable y el sendero ecológico fueron los ambientes con mayor riqueza de especies y abundancia, comparados con el bosque de galería. Durante la temporada lluviosa se registraron 16 especies (ocho exclusivas) y en la seca, nueve especies (una exclusiva). Se registró una mayor riqueza y abundancia de especies durante la época lluviosa. Este es el primer estudio de abejas euglosinas en las sabanas del departamento de Arauca; se reporta una diversidad comparable a otras localidades de Colombia y otros países neotropicales.
Segmentación de imágenes mediante agrupación espectral y medida de similaridad difusa
Authors: Rodríguez-Fernández Juan , Lizarazo-Chilamá Pablo , Muñoz-España Elena , Flórez-Marulanda Juan
Published: June 2022

En los algoritmos de segmentación de imágenes mediante agrupamiento espectral, debido al tamaño de las imágenes, la carga computacional para la construcción de la matriz de similitud y la solución al problema de valores propios para la matriz laplaciana son altos. Además, la medida de similitud más utilizada es el kernel gaussiano, el cual presenta problemas con distribuciones de datos irregulares. Este trabajo propone realizar una presegmentación o diezmado mediante superpíxeles con el algoritmo Simple Linear Iterative Clustering, para disminuir el costo computacional y construir la matriz de similaridad con una medida difusa basada en el clasificador Fuzzy C-Means, que proporciona al algoritmo una mayor robustez frente a imágenes con distribuciones complejas; mediante agrupamiento espectral se determina la segmentación final. Experimentalmente, se comprobó que el enfoque propuesto obtiene segmentaciones adecuadas, buenos resultados de agrupamiento y una precisión comparable respecto a cinco algoritmos, midiendo el desempeño bajo cuatro métricas de validación.
‘Amaliyah al-Ittiṣāl al-Lugawi fī Qaṣaṣ Sūrah al-Kahfi
Authors: Aulia Aly
Published: June 2022

The Qur'an, a holy book revealed by Allah SWT, contains the rules and stories of the previous people to strengthen the truth of Islam. In these stories, there is communication between important figures of the previous people, which contains beautiful literary values so that humans easily understand them. One of them is surah al-Kahf which summarizes four important stories: Ashabul Kahf, Owner of two gardens, Musa and Khidlir, and Dzulqarnain, which contain many unusual functional sentences which show the miraculous factor of the Qur'an from a linguistic perspective. This study aimed to reveal communication (speech) acts and the influence of context on word choice and coherence on the principles of speech contained in the story in finding a model of polite speech acts and felt by the interlocutor more lightly. This research was a pragmatic study that used descriptive qualitative methods through a literature review. In order to describe this speech behavior, this study used the speech acts theory developed by Searle. The analysis showed that various speech acts were performed, namely assertive, directive, commissive, expressive, and declarative, with a specific form of expression or language.
Practical approaches to the use of markers of biochemical hyperandrogenism in women
Authors: Tutchenko T.M. , Burka O.A. , Sidorova I.V. , Nohovska I.H. , Marynchyna I.M. , Shcherbatiei N.M.
Published: June 2022

Hyperandrogenism (HA) remains an actual problem that raises a large number of questions, in particular, in cases of discrepancy between the clinical signs of HA and biochemical parameters. This review includes an analysis of recent studies of androgen synthesis and metabolism in healthy women of reproductive age; management of pathologies accompanied by HA; as well as contemporary approaches to the principles of prescribing and evaluating the results of the main available markers of biochemical HA. There are сoncepts of clinical and biochemical HA. Biochemical HA is an increase in the levels of various circulating androgens. The concept of clinical HA includes hirsutism as assessed by the modified Ferriman–Gallwey scale. The most common causes of HA include polycystic ovary syndrome, non-classical forms of congenital adrenal hyperplasia, other endocrine disorders. It is necessary to carry out a differential diagnosis of these conditions with more rare causes as a primarily tumor pathology. The choice and evaluation of laboratory markers of biochemical HA should be made taking into account clinical data such as puberty history, anovulation, polycystic ovarian morphotype, obesity; presence and degree of hirsutism and/or other androgen-associated dermatopathies, the characteristics of the course of clinical HA (sudden onset, rapid progression), presence of other endocrinopathies, liver and kidney dysfunction; diabetes mellitus. The objectives of the laboratory assessment of HA are determination of HA severity; determination of the source of excess androgen synthesis (ovaries, adrenal glands); assessment of the free fraction of circulating active androgens; in some cases, assessment of the formation of active androgens in the skin. The following indicators are used to solve the tasks in laboratory diagnostics: total testosterone, free testosterone, free androgen index, androstenedione, dehydroepiandrosterone sulfate, 17-hydroxyprogesterone, dihydrotestosterone. A comprehensive assessment of these indicators allows not only assessing the presence of HA and its severity, but also the nature of its leading and secondary components, which determine the presence and prognosis of metabolic risks and allow individualizing therapeutic approaches.
Preserving reproductive health before the first pregnancy
Authors: Kravchenko О.V.
Published: June 2022

Research objective: to evaluate the effectiveness of drugs based on decamethoxine for the treatment of inflammatory diseases of genital organs in adolescent girls entering reproductive age.Materials and methods. The study included 96 patients aged 17–19 years who lived an irregular sexual life. The diagnosis of vulvovaginal infection was verified based on clinical and laboratory data. All patients with vulvovaginal infection received Decasan solution 50–100 ml three times a day in the form of irrigation of the external genitalia for the daytime sanitation and Gynodek vaginal gel 5 ml once at night for 7 days, which provided a night exposure of the antiseptic component and created an environment for the restoration of vaginal lactoflora. The effectiveness of treatment was assessed by the results of clinical and bacteriological examination before and after treatment. The criteria for the effectiveness of treatment were complete clinical and bacterial sanitation.Results. According to the results of the microbiological study, all patients were divided into 3 groups: group I consisted of 36 patients with nonspecific vulvovaginitis, group II – 28 adolescent girls with vulvovaginal candidiasis, group III – 32 patients with mixed bacterial-candidiasis infection.The clinical efficacy of therapy was 95.8%: in group I – 94.4%, in group II – 96.4%, in group III – 96.9%. Bacteriological examination, carried out 2 weeks after the end of the course of treatment, confirmed the effectiveness of therapy in 94.4% of adolescent girls with nonspecific vulvovaginitis, in 89.3% with vulvovaginal candidiasis and in 87.5% with mixed bacterial-candidiasis infection.Conclusions. Topical treatment of inflammatory genital diseases in adolescent girls entering reproductive age is effective, safe and can be considered the therapy of choice. Therapy with drugs based on decamethoxine (Decasan and Gynodek) is highly effective in mono- and mixed vulvovaginal infections, which contributes to the preservation of the reproductive health of adolescent girls at the stage of entering reproductive age.