bluuebunny/crossref_metadata_2025 huggingface dataset:
Tecendo o Verde Urbano:
Authors: Franceschi Lucas Antonio
Published: February 2025

Durante a década de 1970, o desenvolvimento urbano no município de Chapecó, Santa Catarina, viveu uma crescente preocupação com a preservação do meio ambiente e a promoção de espaços verdes dentro das cidades. Nesse contexto, os códigos ambientais desempenham um papel fundamental na regulamentação e proteção dos recursos naturais, orientando as ações voltadas para a conservação e uso sustentável do ambiente urbano. A criação de parques tem sido uma estratégia adotada para conciliar o crescimento urbano com a preservação dos ecossistemas locais e a promoção do bem-estar da população. Este artigo propõe uma análise da relação entre os códigos ambientais e a criação de parques em Chapecó, até a década de 1990, destacando os desafios e oportunidades enfrentados no processo de planejamento e implementação desses espaços verdes. Para tanto, serão considerados aspectos históricos, legais, socioeconômicos e ambientais, através de analise de periódicos do período, visando contribuir para uma compreensão mais ampla do papel dos códigos ambientais na construção de cidades sustentáveis e resilientes.
Evaluation of Lipid Profile Alterations for Early Diagnosis and Therapeutic Management of Cardiovascular and Metabolic Disorders
Authors: Mehmood Arshia , Hafeez Sehrish , Muhammad Wassan Shafi , Kadir Salma , Akram Shamim , Zeb Shah Talmeez
Published: February 2025

Background: Cardiovascular and metabolic disorders are strongly influenced by dyslipidemia, but traditional lipid markers may not fully capture cardiovascular risk. Emerging biomarkers such as non-HDL cholesterol, Apolipoprotein B (ApoB), and lipoprotein(a) [Lp(a)] offer improved risk stratification. This study evaluates lipid profile alterations and assesses the efficacy of lipid-lowering therapies.

Objectives: To compare lipid profile alterations between patients with cardiovascular and metabolic disorders and healthy controls, and to assess the effectiveness of lipid-lowering therapies.

Methods: A cross-sectional study was conducted on 100 participants (50 patients, 50 controls). Lipid assessments included LDL-C, HDL-C, triglycerides, non-HDL-C, ApoB, Lp(a), and oxidized LDL (OxLDL). The effectiveness of statins, PCSK9 inhibitors, and omega-3 fatty acids was analyzed. Statistical significance was set at p < 0.05.

Results: Patients had significantly higher LDL-C (143.7 vs 102.4 mg/dL, p < 0.001), non-HDL-C (162.1 vs 120.3 mg/dL, p < 0.001), triglycerides (187.4 vs 104.3 mg/dL, p < 0.001), and OxLDL (2.1 vs 1.4 µmol/L, p < 0.001), while HDL-C levels were lower (37.6 vs 52.1 mg/dL, p < 0.001). PCSK9 inhibitors reduced LDL-C by 55.3% (p < 0.001), while omega-3 fatty acids lowered triglycerides by 27.1% (p < 0.001).

Conclusion: Nontraditional lipid markers should be incorporated into cardiovascular risk assessment. PCSK9 inhibitors demonstrated superior LDL-C reduction, and omega-3 fatty acids effectively reduced triglycerides. Further research is needed to develop personalized lipid-lowering strategies for improved cardiovascular risk management.

Keywords: Dyslipidemia, Lipid profile, Cardiovascular risk, LDL cholesterol,non-HDL cholesterol, Apolipoprotein B, Lipoprotein(a), PCSK9 inhibitors, Omega-3 fatty acids, Metabolic syndrome.
Postoperative Outcomes and Patient Satisfaction Following Laparoscopic Versus Open Inguinal Hernia Repair: A Comparative Study
Authors: Ali Dal Nawaz , Qureshi Mahak , Memon Samar , Murtaza Ghulam , Sadiq Ch Tanveer , Azhar Shaheer
Published: February 2025

Background: Laparoscopic and open are the two main ways of doing inguinal hernia repair. Laparoscopic repair has advantages including reduced postoperative pain and quicker recovery, however, feasibility, efficacy, and accessibility of this procedure in resource limited settings like Pakistan is not clear.

Objective: To compare, evaluate and quantify the postoperative outcomes, complications, recovery time and patient satisfaction between laparoscopic and open inguinal hernia repair at tertiary care setting in Pakistan.

Methods: This was a prospective comparative study conducted at three tertiary care hospitals in Pakistan. Eighty adult patients with primary unilateral reducible inguinal hernia were randomly assigned to undergo laparoscopic versus open inguinal hernia repair. Operative time, hospital stay and postoperative complications were the primary outcomes. Other outcomes included pain assessment by the Visual Analog Scale (VAS), return to normal activities, and patient satisfaction. SPSS version 26.0 was used to perform statistical analysis, significance of p < 0.05.

Results: Operative time was longer with laparoscopic repair (91.2 ± 14.7 min vs. 57.9 ± 11.5 min, p < 0.001) but shorter with hospital stay (1.1 ± 0.5 days vs. 2.5 ± 1.0 days, p < 0.001). There was significantly lower postoperative pain in the LIHR group (p < 0.001). The total complication rates were lower in the laparoscopic group (7.5 vs. 15.0, p = 0.048). The patients who have undergone laparoscopic repair were found to be more satisfied with the outcome.

Conclusion: The postoperative outcomes after laparoscopic inguinal hernia repair are better, such as less pain, less time in hospital and faster recovery. Despite it, in Pakistan its adoption is limited to due to cost and training requirements.

Keywords: Inguinal hernia, Laparoscopic repair, Open repair, Postoperative outcomes, Patient satisfaction, minimally invasive surgery, Pakistan.
Therapeutic Significance of Bala (Sida cordifolia Linn.): A Systematic Review
Authors: Paijwar Dr. Priya , Mishra Prof. Deepa , H. Awasthi Senior Prof. H.
Published: February 2025

Bala (Sida cordifolia Linn.), a prominent herb in Ayurveda, has been utilized for centuries for its diverse therapeutic benefits. Sida cordifolia belongs to the Malvaceae family and is recognized for its wide-ranging medicinal properties, documented in ancient texts such as the Vedas, Samhitas and Nighantus. Various parts of the plant, including roots, leaves, and seeds, contain bioactive compounds such as alkaloids, fatty oils, steroids, and ephedrine, contributing to its medicinal effects. The drug is attributed Balya, Kantikaraka, Grahi, Vrishya, Ojovardhaka, Stambhana, Brihmana, Shothahara and Hridya properties in different Ayurvedic Classical texts. The plant's pharmacological activities, including anti-inflammatory, analgesic, hypoglycemic, antimicrobial, and anticancer properties, are supported by scientific research. The aim of this study is to systematically review the scientific literature on the effects of Bala (Sida cordifolia) and to consolidate botanical, traditional, and modern pharmacological insights to provide a comprehensive understanding of its therapeutic potential. This research could pave the way for innovative applications in modern medicine, emphasizing its significance in developing effective, natural, and sustainable treatments for various diseases.
Employee Excellence and Workplace Diversity
Authors: Hatidja St , Bahtiar  , Mariana Lina , Quach Tai Minh , Aisyah Siti
Published: February 2025

This study investigates how employee skills and workplace diversity influence customer satisfaction, brand awareness, and employee retention in Indonesian restaurants in Taiwan. Using Structural Equation Modeling (SEM), the research explores the direct and indirect effects of these variables, with customer satisfaction acting as a crucial mediator. The findings highlight that employee skills significantly enhance customer satisfaction, which directly strengthens brand awareness and customer retention. Likewise, workplace diversity enriches customer experience, improving satisfaction and broadening brand reach. Notably, customer satisfaction mediates the relationships between employee skills, workplace diversity, and retention, underscoring its pivotal role in linking workforce dynamics to business outcomes. This paper contributes to Human Capital Theory and Social Exchange Theory, emphasizing the strategic value of developing employee skills and fostering workplace diversity. Practical implications suggest that restaurant owners should invest in training programs and inclusive workplace policies to enhance customer experience, build brand loyalty, and reduce employee turnover, ultimately driving business success.
Driving Agricultural Productivity in Indonesia
Authors: Sulfiana Sulfiana
Published: February 2025

This study examines the impact of digital transformation on agricultural productivity across Indonesia, focusing on the roles of digital infrastructure, technology adoption, farmer education, government support, and cost of technology. Using a multiple regression model with data from 380 respondents across key agricultural regions, the findings reveal that technology adoption and government support have the most substantial impacts on productivity. Digital infrastructure and education also play significant roles, while the cost of technology has a smaller yet positive effect. The study highlights regional disparities, with Java and Sumatra benefiting most from digital transformation, while regions like Maluku and Papua face challenges due to limited resources and infrastructure. These findings emphasize the need for integrated policies targeting infrastructure development, education, and affordability to ensure inclusive growth. This research contributes to the understanding of digital transformation in agriculture and provides actionable insights for sustainable agricultural development
Artes em sociais aprendizagens como encontro com a experiência e o autocultivo: ensaiando rupturas ao sistema, às práticas bancárias e ao habitus conservatorial
Authors: Abreu Yure Pereira de , Matos Elvis de Azevedo , Ribeiro Luís Távora Furtado , Barbosa Gardenia Maria de Oliveira , Lima Carlos Rochester Ferreira de
Published: February 2025

Este artigo propõe uma reflexão sobre a Pedagogia denominada Artes em Sociais Aprendizagens: ASAS. A partir dos escritos de Paulo Freire (2016), de suas críticas ao modelo “bancário de educação”, assim como, de sua propositura de uma educação libertadora, articuladas com as reflexões de Jorge Larrosa (2022) sobre o conceito de experiência e também aludindo ao que Marcus Pereira (2012) denominou como Habitus Conservatorial, empreende-se, esta reflexão sobre  pedagogia das Artes em Sociais Aprendizagens (ASAS), tal como apresentada por Abreu (2024). As ASAS propõem um novo modelo pedagógico para o ensino das artes na educação básica, ao buscar romper com a educação bancária e o Habitus Conservatorial. Para tanto, as ASAS se fundamentam na experiência, tal qual definida por Larrosa, como elemento central de todo o processo de aprendizagem. Nesta abordagem a ênfase é conferida à compartilha de saberes, realizada em meio a relações horizontais e dialógicas, de modo a valorizar as experiências singulares de cada sujeito. O objetivo central das ASAS está em desenvolver, de forma integral, o ser humano, em todas suas potencialidades, integrando as dimensões cognitivas, sensíveis, emocionais e éticas. Para tanto, as ASAS buscam romper com a lógica hierarquizante e compartimentalizada do campo artístico e educacional, de modo a promover uma visão democrática e ampla da educação artística. Esta pedagogia se assenta na compreensão de que todos os envolvidos são, assim, sujeitos ativos do processo, estimulando o desenvolvimento da criatividade, da criticidade e da reflexão. Nas conclusões deste trabalho são apresentados argumentos que embasam a afirmação  de que as ASAS oferecem um caminho viável para a transformação social e o autocultivo, por meio da construção de um ambiente educacional mais justo, emancipador e criativo, evocando a imagem de um voo coletivo, no qual  todos aprendem em comunhão, buscando uma sociedade mais humana e solidária, através das artes.
A influência do Orçamento Participativo na Qualidade da Informação Contábil e Fiscal nos municípios brasileiros
Authors: Marques Fernanda Larrúbia , Oliveira Alessandro Bandeira de , Costa Claudio Luiz de Oliveira , Oliveira José Marcelo Velloso de
Published: February 2025

Este estudo investiga se os municípios brasileiros que implementaram o Orçamento Participativo (OP) apresentam Qualidade da Informação Contábil e Fiscal (QICF) superior. Utilizando dados de 2019 e 2020, aplicaram-se modelos econométricos, incluindo Mínimos Quadrados Ordinários Agrupados (Pooled) e modelos de dados em painel. Os resultados indicam que municípios que adotaram o OP apresentam maior QICF, com PIB per capita e eficiência no planejamento positivamente correlacionados. O estudo preenche uma lacuna ao relacionar OP e QICF, oferecendo evidências empíricas que contribuem para a literatura sobre finanças públicas e participação cidadã. Além disso, valida modelos econométricos e amplia o debate sobre práticas participativas. No campo prático, sugere que o OP pode melhorar a transparência e a eficiência da gestão pública, reforçando sua relevância como instrumento de governança democrática. Dessa forma, a pesquisa fortalece o entendimento sobre os impactos do OP na qualidade da informação contábil e fiscal nos municípios brasileiros, contribuindo para políticas públicas mais eficazes.
Development and Assessment of an Herbal Bath Soap Enriched with Plant Extracts
Authors:   Department of Analytical Chemistry, 'Chaitanya 'Bombale Patil Nagar Chavan Hospital Road Ward No 7 Shrirampur Ahmednagar, Ahmed Nagar (Maharashtra), India., Prakash Metkar Aditi
Published: February 2025

The primary aim of this study is to develop an ecofriendly Ayurvedic bath soap using water-based extracts of plants with dermatological benefits as described in Ayurveda, specifically Orange peel, Aloevera and Almond oil. Orange peel were extracted in water, and this extract was combined with oils and lye in a saponification process to produce the soap. The resulting soap was assessed for physicochemical properties, including total fatty matter, moisture content, and pH, demonstrating favorable characteristics across these parameters. The formulated soap is suitable for all skin types. With further standardization, it may serve as an alternative to commercial medicinal soaps for skin whitening and acne treatment.
Utilizing 64-QAM for Enhanced Data Transmission in Underwater Optical Communication System
Authors:   Department of Information and Communication, Al-Khwarizmi College of Engineering, University of Baghdad, Iraq., Al-Mashhadani Zinah A.
Published: February 2025

Underwater acoustic channels are affecting by many factors like time varying multipath propagation, Doppler spread, and salinity, which can greatly limit the quality of data rate and transmission distance. Underwater optical communication represents a crucial technology that supporting higher data rate, secure links and low latency. In his paper the use of 64- Quadrature Amplitude Modulation (64-QAM) in underwater optical communication systems is investigated. The system is designed to offer higher data rate than those of acoustic communication system. The proposed design achieve data rate of 10 Gbps over a challenging transmission distance of 50 km. In our study, a simulation technique is used to evaluate the performance of the proposed design in the underwater conditions, focusing on factors such as Bit Error Rate (BER), constellation diagram and Quality factor (Q-factor). The achieved BER is of about 10-10 with a minimum signal to noise ratio (SNR) of about 30dB. This paper provides valuable results for the design of next-generation underwater communication systems for applications such as pollution monitoring, oil control and oceanography research.
Evaluation of Performance Accountability In Tourism Development: Case Study at The Youth, Sports and Tourism Office of Sidenreng Rappang District
Authors: Azzahra Nadia , Jabbar Abdul , Irwan Irwan , Mustanir Ahmad , Tamrin Muh.
Published: February 2025

This study aims to evaluate the Accountability of performance in the tourism sector of the Youth, Sports, and Tourism Office (Disporapar) of Sidenreng Rappang Regency to achieve transparent and effective regional development targets. Using a qualitative descriptive approach, data was collected through observation, interviews, and document analysis from June to July 2024 and analysed using the Nvivo 12 Plus application. The study results revealed that Disporapar had achieved most of the targets set in the 2023 Regional Apparatus Work Plan (RKPD) despite facing obstacles such as budget limitations and the quality of human resources. Priority programs such as improving human resource competence, developing tourist areas, and implementing various trainings have been successfully implemented and have a positive impact on increasing regional tourism attractiveness. Performance accountability assessments are based on five dimensions: legal and honesty, managerial, programmatic, policy, and financial. The findings show that program accountability is the most dominant dimension, with the success of most programs in achieving the set goals. Legal Accountability, honesty, and managerial Accountability also showed good performance, although there was room for improvement in financial reporting and transparency. In conclusion, the Accountability of the performance of the Sidenreng Rappang Regency Disporapar is quite good in achieving regional tourism development targets. However, improvements in several aspects are needed to ensure the effectiveness and efficiency of program implementation and the fulfilment of accountability obligations to the public.
Comparing Teachers’ Critical Thinking Skills in Terms of the School Types through Classical Logic and Fuzzy Logic
Authors:   Akdeniz University, Faculty of Education, Educational Administration Department, Antalya, 07058, Turkey, Abdullah Abdullah ,   Department of Mathematics, Gaziantep University, Gaziantep 27310, Turkey,   Department of Educational Sciences, Gaziantep University, Gaziantep 27310, Turkey, Kargin Abdullah , Şahin Sevilay �
Published: February 2025

This study is an attempt to explore the value of the teachers’ critical thinking skills with fuzzy expert systems. The study employed this system to obtain an objective and authentic evaluation in an abstract or ambiguous assessment. The working group consisted of 275 teachers working in public schools in Antalya central districts during the 2021-2022 academic year. This study deployed The Critical Thinking Appraisal (CTA) developed by Özelçi (2012). In the first stage, the data obtained from the teachers' critical thinking skill scale were analyzed through classical logic. Validity (explanatory and confirmatory factor analysis) and reliability analyzes (Cronbach Alpha) were performed during data analysis. Besides, the data regarding the teachers' critical thinking skill scale were also examined through the fuzzy logic approach. Different results emerged when comparing both methods. The findings revealed that the result on the fuzzy logic approach, which underpins artificial intelligence applications and which is used in various decision-making applications, is more consistent and objective. This study may shed light onto the researchers to obtain results that are more objective by conducting studies based on fuzzy logic-based survey. Besides, the validity and reliability analyzes made through the classical method with a similar method may also be carried out through the fuzzy logic method. These new results may be compared with those of the classical method. Thus, the objectivity of classical validity and reliability analyzes may also be examined.
Positive psychology research within the workplace in Namibia: Findings and prospects for the future
Authors:   Department of Psychology and Social Work, Pieters Wesley ,   University of Namibia, Windhoek, Namibia
Published: February 2025

The field of Psychology has been criticised as being overly focused on pathology and less on the positive aspects of human functioning. Positive psychology research assesses what is going well and try to find ways to learn from those phenomena to enhance positive functioning amongst human beings. Making use of a desk study review, this study discusses research related to Positive psychology conducted in Namibia related to the world of work. This study focused on research work published during 2009-2019 within different industries ranging from education, health and social services, governmental institutions, service industry and the mining sector. Recommendations span from enhancing the positive human qualities, identifying factors that work against positive functioning, enhancing the working environment, improving healthy styles of leadership and developing the overall well-being of the organisation. This study aims to consolidate what has been researched within the Namibian context, taking stock and guiding the future approaches and focus within the field of Positive psychology. There is limited research within the field of Positive psychology and even less within the Namibian context. This study aims to reduce that gap within knowledge and within the field of psychology.
Prevalence of Mental Disorders Among Healthcare Workers After the Pandemic in Vietnam and Associated Factors: a Cross-sectional Study
Authors: Sinh Nguyen , Hoa Le , Duc Nguyen , Hoa Tran , Dung Nguyen
Published: February 2025

Background: The COVID-19 was declared no longer a global health emergency. The mental health of healthcare workers has become a critical concern, highly impacted by the COVID-19 pandemic. Objective: This study aimed to determine the prevalence of mental disorders among healthcare workers in Vietnam and the associated factors in the post-pandemic era. Methods: A cross-sectional descriptive study was conducted at Hung Vuong Hospital, Vietnam. A self-administered questionnaire was distributed to 660 healthcare workers, and the outcomes were assessed using the DASS-21 scale. Results: The participants’ ages ranged from 22 to 62 years, with 66.2% female. The majority were nurses (48.9%) and doctors (25.8%). A significant proportion worked in clinical sectors (77.9%) and had less than 10 years of work experience (84.4%). Overall, 39.5% of participants had at least one mental disorder, specifically, 31.7% had anxiety, 16.2% had stress, and 18.9% had depression. Significant associated factors included pressure from administrative duties (aOR = 2.15, 95% CI 1.39–3.35), intensive work (aOR = 1.69, 95% CI 1.13–2.55), relationships with colleagues (aOR = 1.59, 95% CI 1.10–2.29), and perceived fairness in work-performance evaluations (aOR = 1.88, 95% CI 1.22–2.91). Conclusion: The mental disorders among healthcare workers in Vietnam remained relatively high after the pandemic. Interventions should prioritize work-environmental factors including pressure from administrative duties, intensive working, the absence of good relationships with colleagues, and the fairness in work-performance evaluation.
Effect of Sleeper One® 5 Anesthesia Device on Heart Rate

Running Title: Effect of Sleeper One® 5 Device on Heart Rate
Authors: AN zg , DERTL Fatma , AN zge , AN Suat , LKER G
Published: February 2025

Aim: This study compares the pulse parameter values before, during, and after anesthesia using computer-assisted local infiltration anesthesia and traditional local infiltration anesthesia methods in children.
Materials and Methods: The study included 100 children aged 7-11 who applied to the pediatric dentistry clinic. During the initial session, the children underwent intraoral examinations. The children were divided into two groups randomly. Traditional local infiltration and computer-assisted local anesthesia were applied to treat dentin caries in the maxillary primary molar teeth. The heart rate of the patients was measured using a pulse oximeter device.
Results: The average age of the patients was 8.21±1.00 years, with 48 (48.0%) male and 52 (52.0%) female. The average heart rate (HR) was found to be 99.28±14.68. At the end of the study, 61 (61.0%) of the patients preferred the computer-assisted anesthesia method, and 39 (39.0%) preferred the traditional method. A notable distinction exists between the pre- and post-anaesthesia heart rate values associated with each anaesthesia technique, indicating significant variations when comparing different methods of anaesthesia (p<0.001). No significant differences were observed between the two methodologies across all measured values (p>0.05).

Conclusion: Although there was no significant difference in heart rate parameters, 61% of the patients preferred the computer-controlled local anesthesia method, which showed effectiveness in reducing anxiety. Further studies are required to confirm these results using modern local anesthesia devices.
Effects of sertraline on episodic memory in chronic mild stress model of depression in rats
Authors: solak Hat , gormus z , koca raviye , zdemir ayse , soy mehmet , kurar ercan , kutlu selim
Published: February 2025

Aim: Individuals with depression have cognitive deficits, including diminished thinking and concentration ability, as well as memory difficulties. Certain antidepressants used for depression are recognised to positively influence cognitive functions, including learning and memory. We aimed to examine the impact of sertraline, a selective serotonin reuptake inhibitor (SSRI), on learning and memory metrics as well as hippocampus cell proliferation in depressed rats caused by a chronic mild stress (CMS) model.
Materials and Methods: 48 rats were allocated into four groups:C, CMS, CMS+S and S. CMS groups were subjected to various stressors for a duration of 15 days.On day 15, an open field test (OFT) and a forced swim test (FST) were conducted.S was delivered at a dosage of 10 mg/kg/day for a duration of 15 days using an osmotic minipump. The OFT, Elevated Plus Maze (EPM), Forced Swim Test (FST), and Novel Object Recognition Test (NORT) were conducted to assess the efficacy of S. Animals were beheaded, and hippocampal tissues were excised. Quantitative RT-PCR was employed to assess the expression levels of peptide genes (BDNF, NeuN, MASH1).One-Way ANOVA was employed for statistical analysis.
Results: In the CMS group, there was a significant decrease in OFT velocity and movement percentage compared to the control group (p<0.001). There was a significant decrease in swimming, climbing and immobilization times in the CMS group compared to the other groups. There was a significant increase in swimming speed in the CMS+S group (p<0.001). In the NORT long-term memory analysis, there was a significant increase in the recognition and discrimination index in the CMS+S group compared to the CMS group (p<0.01). There was a significant decrease in gene expression levels in hippocampal tissues (BDNF, NeuN, MASH1) in the CMS group and a significant increase in the CMS+S group (p<0.05).
Conclusion: The study shows that sertraline in the treatment of depression is beneficial in improving cognitive abilities by increasing gene expression in the hippocampus. It is thought that serotonin improves long-term memory and may positively affect the regulation of brain precursor cell formation.
Medicinal Uses, Prevalence, and Mechanism of Action of Nigerian Plants with Psychoactive Properties
Authors: Yussuf Mubaraq , Kokelu Anthony , Kelvin Emmanuel , Gomina Muftanatu , Usman Sa , Nweze Victory , Aluko Elizabeth , Umeh Ikechukwu , Bello Adeola
Published: February 2025

Nigeria’s rich biodiversity hosts various psychoactive plants that have been pivotal in traditional medicine and cultural practices. This review examines the medicinal uses, prevalence, and mechanisms of action of prominent Nigerian psychoactive plants, including Datura stramonium and Carica papaya. These plants, utilized for centuries, exhibit pharmacological activities such as anti-inflammatory, analgesic, and neuroactive effects, driven by their bioactive compounds like alkaloids and flavonoids. Traditional applications range from treating ailments like asthma, depression, and infections to roles in spiritual rituals. However, the recreational use and neurotoxic potential of these plants have raised public health concerns, particularly regarding substance abuse. This review highlights the need for a deeper understanding of their therapeutic benefits and risks, emphasizing the importance of culturally sensitive and evidence-based research. Insights from this study aim to inform clinical practice and shape policies to promote the safe and effective use of these plants in modern medicine.
IMPROVING STUDENTS’ SPEAKING SKILL THROUGH PICTURE SERIES AT THE GRADE X OF ISLAMIC BOARDING SCHOOL OF SABBHISMA PADANG
Authors: Lailatul Husna  , Dedi Dedi
Published: February 2025

This research was classroom action research [CAR] because the research aimed at finding out the practical problem solving. Jhonson (2005) states classroom action research is a process of studying class situation or real class in improving and understanding the quality of action or instruction. the students prefer using Indonesian language in speaking with their friends, teachers, and other people. These cases are caused by some factors; students’ input, limited facilities, unsupported school environment and teacher strategies that used in teaching and learning process in the classroom. the comparison the students’ speaking test between speaking test I and speaking test II. At the speaking test I, the students’ purpose was 6.6 , the score increased to be 8.2 on the speaking test 2. The data of using picture series in teaching and learning recount text showed that it could improve the students’ speaking skill because the picture series were consisted a set of pictures, including sequences of events that create a story.
Representações sociais de adolescentes escolares sobre saúde sexual e reprodutiva
Authors: Rocha Oliveira Jardelson , Araújo Moreira Michelle
Published: February 2025

Este trabalho tem como objetivo entender como ocorrem as representações sociais de adolescentes sobre saúde sexual e reprodutiva. Para isso, fez-se um estudo intervencionista, qualitativo e exploratório, ancorado na Teoria das Representações Sociais, realizado em uma escola pública da Bahia, com 28 estudantes. A coleta dos dados ocorreu por meio das técnicas de entrevista semiestruturada e grupo focal, analisadas por técnica de análise de conteúdo temático. As representações sociais dos adolescentes versaram sobre as mudanças corporais dessa fase, conceitos atribuídos à identidade de gênero e orientação sexual, a importância do sexo e da primeira relação sexual e o autocuidado através da importância atribuída aos preservativos e à contracepção hormonal. Identificou-se a necessidade de intervenção profissional no ambiente escolar para preencher as lacunas na promoção da saúde sexual e reprodutiva das(os) adolescentes.
A vez e a voz das crianças
Authors: Braga Ilze , Ribeiro Marcelo Silva de Souza
Published: February 2025

O presente estudo, de abordagem qualitativa, tem como objetivo analisar os direitos das crianças a partir das interpretações infantis. Fundamentou-se teoricamente no sociointeracionismo, com base na Psicologia e Sociologia da Infância. A coleta de dados foi realizada com crianças de 7 a 11 anos, por meio de desenhos cujo tema foi os direitos das crianças, além de entrevistas sobre o mesmo assunto. Os resultados foram obtidos por meio da análise de conteúdo de Bardin (2006), incorporando elementos do contexto da pandemia de covid-19 e evidenciando que as crianças possuem conhecimentos gerais sobre seus direitos fundamentais: família, brincadeira, moradia, educação e saúde. Este trabalho ressalta a importância da participação infantil, destacando que essa prática é não apenas possível, mas também necessária. Constatou-se, finalmente, que quanto mais informações a criança tiver acesso, mais ela poderá contribuir para a sociedade.
Modeling Dependence of Peak Floor Acceleration and Maximum Interstory Drift Ratios with Gaussian Copulas
Authors: Munjy Huda , Botros Stephanie
Published: February 2025

This study introduces a multivariate demand model for Engineering Demand Parameters (EDPs) in Performance Based Seismic Design (PBSD), utilizing Gaussian copulas to characterize the dependence structure of the demand vector. The effectiveness of this approach is assessed by comparing EDPs generated using Gaussian copulas against those assumed under a joint lognormal distribution. This validation study is further carried forward to values of economic loss for the four special steel moment frames obtained via the three sets of EDPs. The Performance Assessment Calculation Tool (PACT) developed by the Federal Emergency Management Agency (FEMA) P-58 (2015) is used for loss estimation. Results indicate that using copulas to represent the dependence structure of EDPs better captures the characteristics of the population of EDPs rather than assuming a joint lognormal distribution. Distributions of economic loss generated using copulas match the loss generated from the true observations of EDPs better than loss generated assuming a joint lognormal distribution. The sample size of the selected and scaled ground motions required for the generation of realizations of building response via nonlinear dynamic analysis is also investigated, which proves to yield more accurate values of response but, at the expense of using a larger number of initial observations.
Novel association between graft rejection and post-transplant malignancy in solid organ transplantation
Authors: Kim Hye Sung , Woo Wongi , Choi Young-Geun , Bharat Ankit , Chae Young Kwang
Published: February 2025

BACKGROUND

Advancements in immunosuppressive therapies have improved graft survival by enhancing graft tolerance and preventing organ rejection. However, the risk of malignancy associated with prolonged immunosuppression remains a concern, as it can adversely affect recipients’ quality of life and survival. While the link between immunosuppression and increased cancer risk is well-documented, the specific interactions between graft rejection and post-transplant malignancy (PTM) remain poorly understood. Addressing this knowledge gap is crucial for devising immunosuppressive strategies that balance rejection prevention with cancer risk reduction.

AIM

To investigate whether immunosuppression in PTM reduces rejection risk, while immune activation during rejection protects against malignancy.

METHODS

We analyzed data from the United Network for Organ Sharing’s Organ Procurement and Transplantation Network database (1987–2023) on adult, first-time, single-organ transplant recipients with no prior history of malignancy (in donors or recipients). Landmark analyses at 1, 2, 3, 5, 10, 15, and 20 years post-transplant, Kaplan–Meier analyses, and time-dependent Cox proportional hazards regression models, each incorporating the temporal dimension of outcomes, assessed the association between rejection-induced graft failure (RGF) and PTM. Multivariate models were adjusted for clinical and immunological factors, including immunosuppression regimens.

RESULTS

The cohort included 579905 recipients (kidney: 386878; liver: 108390; heart: 45046; lung: 37643; pancreas: 1948) with a mean follow-up of 7.3 years and a median age of 50.6 ± 13.2 years. RGF was associated with a reduction in PTM risk across all time points [hazard ratio (HR) = 0.07-0.20, P < 0.001], even after excluding mortality cases. Kidney transplant recipients exhibited the most pronounced reduction (HR = 0.22, P < 0.001). Conversely, among recipients with PTM, RGF risk decreased across all time points up to 15 years after excluding mortality cases (HR = 0.49–0.80, P < 0.001). This risk reduction was observed in kidney, liver, heart, and lung transplants (HRs = 0.90, 0.21, 0.21, and 0.18, respectively; P < 0.001) but not in pancreas transplants.

CONCLUSION

RGF reduces PTM risk, particularly in kidney transplants, while PTM decreases RGF risk in kidney, liver, heart, and lung transplants.
Clinical events and healthcare resource utilization associated with neutropenia and leukopenia among adult kidney transplant recipients receiving valganciclovir
Authors: Beyer Andrew P , Moise Pamela A , Wong Michael , Gao Wei , Xiang Cheryl , Shen Pangsibo , Pavlakis Martha , Vincenti Flavio , Wang Weijia
Published: February 2025

BACKGROUND

Cytomegalovirus (CMV) prophylaxis with valganciclovir and ganciclovir is associated with elevated neutropenia and leukopenia risk in kidney transplant recipients, although the impact of these events on healthcare resource utilization (HCRU) and clinical outcomes is unclear.

AIM

To quantify clinical events and HCRU associated with neutropenia and leukopenia among adults receiving valganciclovir and/or ganciclovir post-kidney transplantation.

METHODS

Adult kidney transplant recipients receiving valganciclovir and/or ganciclovir prophylaxis were identified in the TriNetX database from 2012 to 2021. Patient characteristics were evaluated in the 1-year period pre-first transplant. HCRU and adjusted event rates per person-year were evaluated in follow-up year 1 and years 2-5 after first kidney transplantation among cohorts with vs without neutropenia and/or leukopenia.

RESULTS

Of 15398 identified patients, the average age was 52.39 years and 58.70% were male. Patients with neutropenia and/or leukopenia had greater risk of clinical events for CMV-related events, opportunistic infections, use of granulocyte colony stimulating factor, and hospitalizations (relative risk > 1 in year 1 and years 2-5). Patients with vs without neutropenia and/or leukopenia had higher HCRU in year 1 and years 2-5 post kidney transplantation, including the mean number of inpatient admissions (year 1: 3.47 vs 2.76; years 2-5: 2.70 vs 2.29) and outpatient visits (48.97 vs 34.42; 31.73 vs 15.59, respectively), as well as the mean number of labs (1654.55 vs 1182.27; 622.37 vs 327.89).

CONCLUSION

Adults receiving valganciclovir and/or ganciclovir prophylaxis post-kidney transplantation had greater risk of neutropenia and/or leukopenia, which were associated with higher clinical event rates and HCRU up to 5 years post-transplantation. These findings suggest the need for alternative prophylaxis options with lower myelosuppressive effects to improve patient outcomes.
Personalized translational medicine: Investigating YKL-40 as early biomarker for clinical risk stratification in hepatocellular carcinoma recurrence post-liver transplantation
Authors: Lulic Ileana , Lulic Dinka , Pavicic Saric Jadranka , Bacak Kocman Iva , Rogic Dunja
Published: February 2025

Hepatocellular carcinoma (HCC) recurrence after liver transplantation (LT) presents a significant challenge, with recurrence rates ranging from 8% to 20% globally. Current biomarkers, such as alpha-fetoprotein (AFP) and des-gamma-carboxy prothrombin (DCP), lack specificity, limiting their utility in risk stratification. YKL-40, a glycoprotein involved in extracellular matrix remodeling, hepatic stellate cell activation, and immune modulation, has emerged as a promising biomarker for post-LT surveillance. Elevated serum levels of YKL-40 are associated with advanced liver disease, tumor progression, and poorer post-LT outcomes, highlighting its potential to address gaps in early detection and personalized management of HCC recurrence. This manuscript synthesizes clinical and mechanistic evidence to evaluate YKL-40’s predictive utility in post-LT care. While preliminary findings demonstrate its specificity for liver-related pathologies, challenges remain, including assay standardization, lack of prospective validation, and the need to distinguish between malignant and non-malignant causes of elevated levels. Integrating YKL-40 into multi-biomarker panels with AFP and DCP could enhance predictive accuracy and enable tailored therapeutic strategies. Future research should focus on multicenter studies to validate YKL-40’s clinical utility, address confounding factors like graft rejection and systemic inflammation, and explore its role in predictive models driven by emerging technologies such as artificial intelligence. YKL-40 holds transformative potential in reshaping post-LT care through precision medicine, providing a pathway for better outcomes and improved management of high-risk LT recipients.
Política cognitiva e extensão universitária
Authors: Benini Elcio Gustavo , Freitas de Oliveira Junior Oséias
Published: February 2025

A presente pesquisa tem por objetivo analisar a produção em torno dos conceitos de tecnociência solidária e política cognitiva na abordagem das pesquisas sobre extensão universitária. Por meio de uma pesquisa bibliográfica que se utilizou da ferramenta ProKnow-C, foram analisados 10 estudos que se ocupam da produção de alimentos em comunidades tradicionais. Assim, o estudo fez um levantamento das lacunas existentes em pesquisas futuras que abordem os projetos de extensão universitária em comunidades tradicionais com foco na produção de alimentos. Dessa forma, concluiu-se que há uma série de tópicos e características que podem ser exploradas em pesquisas futuras, em especial os confrontos culturais e a mudança nas políticas de gestão e direcionamentos dos saberes acadêmicos.
Projetos formativos nas crises da modernidade
Authors: Ortega Bárbara , Pich Santiago , Bresolin Maia Caroline
Published: February 2025

Este artigo examina os impactos do neoliberalismo sobre as instituições modernas, com foco na escola pública brasileira. A investigação centra-se em como as crises geradas pelo modelo neoliberal reconfiguram os projetos de formação humana e moldam subjetividades, conforme discutido por Lazzarato (2014), contribuindo para um colapso do sentido e da função da escola. A análise destaca o impacto das reformas educacionais no contexto da crise de subjetividades (Fraser e Jaeggi, 2020), que orientam a educação para uma lógica de controle contínuo, formação permanente, eficiência e auto-otimização. Nesse cenário, a Base Nacional Comum Curricular (BNCC) surge como um exemplo paradigmático de alinhamento às demandas do mercado, ao adotar a Pedagogia das Competências como eixo central. O texto conclui ressaltando a necessidade urgente de reimaginar políticas educacionais que transcendam a lógica econômica, promovendo valores de justiça social e uma formação integral que resgate o sentido crítico e emancipador da escola.
Enhancing Security with Android's SafetyNet API
Authors: Duggirala Jagadeesh
Published: February 2025

As mobile applications become increasingly central to everyday life, the importance of securing them against threats
has grown significantly. Android’s SafetyNet API provides developers with tools to assess the integrity of devices,
detect potentially harmful behavior, and protect sensitive data. This paper explores the features, benefits, and
implementation strategies of the SafetyNet API, highlighting its role in strengthening application security and user
trust. Additionally, we analyze its integration in different app categories and discuss how SafetyNet mitigates specific
security threats.
Keywords
android applications, security, encryption, safetynet api
Extraction and Characterization of Dietary Fiber, Starch and Cellulose Microfibers from Field Bean and Cowpea Pods
Authors:   Department of Food and Nutritional Sciences  Sri Sathya Sai Institute of Higher Learning, Anantapur, Andhra Pradesh, Sai Maddi Harika
Published: February 2025

In today’s modern world, there are lot of food losses and wastages during processing of foods, both at household and industrial level.  These food processing wastes are rich in essential nutrients like carbohydrates, protein, fiber and phytochemicals which are very essential for maintenance of health and treatment of diseases like CVD, DM, Cancer etc. A study on field bean peel and cowpea peel was carried out to check its nutrient composition, phytochemical composition, in vitro anti-oxidant assessment and functional properties. Fiber and starch extracted from peels was studied for their functional properties. The sources proved to be a good source of fiber and starch which was also proved by the results of functional properties. The cellulose microfibers were extracted and characterized by FTIR Spectrophotometer and result showed absence of lignin in extracted CMF and it can further be used in developing biodegradable packaging material.

Keywords: Field bean pods, cowpea pods, Fiber, starch, Phytochemicals, anti-oxidants, cellulose microfibers.
Eco-Friendly Business Practices in Technopreneurship
Authors:   Associate Professor of Commerce,  St. Joseph's College (Autonomous), Tiruchirappalli,  Affiliated to Bharathidasan University, Tiruchirappalli, Tamil Nadu, India., Mariadoss, Dr.S.
Published: February 2025

The increasing integration of eco-friendly business practices within the dynamic field of technopreneurship. It examines the key drivers behind this trend, including growing consumer demand for sustainable products and services, increasing investor interest in environmentally responsible ventures, stricter environmental regulations, rapid advancements in green technologies, and a rising sense of ethical responsibility among entrepreneurs. (Bouarar et al., 2022; Mrkajic et al., 2017; Potluri & Phani, 2020) The paper provides a detailed analysis of various eco-friendly business practices, such as sustainable product design, green supply chain management, energy efficiency, waste reduction and recycling, and the adoption of renewable energy sources. It also discusses the challenges and opportunities faced by technopreneurs in implementing these practices, highlighting the potential for enhanced brand reputation, attracting investment, gaining a competitive advantage, and meeting regulatory requirements. The paper concludes by emphasizing the importance of eco-friendly practices in creating a more sustainable future and the significant role of technology-driven startups in driving this positive change. (Trapp & Kanbach, 2021)

This expanded research paper delves deeper into the intersection of technology, entrepreneurship, and environmental sustainability. It examines the drivers, practices, challenges, and opportunities associated with eco-friendly technopreneurship, providing a comprehensive overview of this evolving field.
Pengaruh Penggunaan Teknologi Big Data dan Efisiensi Operasi Terhadap Kinerja Keuangan Perusahaan Perbankan
Authors: Nurdhianto Nugroho
Published: February 2025

The development of technology, especially Big Data, has brought significant changes in the banking industry by enabling the optimisation of risk analysis, increased operational efficiency, and more accurate decision-making. However, the impact of the application of Big Data on the financial performance of banks in Indonesia has not been widely studied empirically. This study aims to analyse the effect of the use of Big Data technology and operational efficiency on the financial performance of banks in Indonesia. Using a quantitative approach, this study processes secondary data from the annual reports of 12 banks classified as Core Capital Bank Group (KBMI) 3 during the period 2021-2023. The independent variables in this study include the application of Big Data and operational efficiency as measured by the ratio of operating expenses to operating income (BOPO), while financial performance is measured using the CAMEL method. The data was analysed using multiple linear regression after going through a series of classical assumption tests. The results show that although the adoption of Big Data in the banking sector has increased in recent years, it has not had a significant impact on the financial performance of banks. Similarly, operational efficiency as measured by BOPO does not have a significant relationship with financial performance. Overall, the findings indicate that other factors, such as capital policy, risk management, and regulation, have a more dominant influence on banks' financial stability and performance.