bluuebunny/crossref_metadata_2025 huggingface dataset:
Restoration techniques of fractured endodontically treated teeth
Authors: Al-Hussain Abdullah Fahad , Alkhathami Mohammed Mesfer , Almesfer Khalid Mabrouk , Mohammed Abdulrahman Madwas , AlRajeh Abdullah Mansour , Alasmri Mohammed Ali , Kehaili Ohud Awwadh , Alresheedi Sultan Falah , Alotaibi Ahmed Fadgoosh , Almutairi Muqbil Jazaa , Alibrahim Wesam Yousef
Published: July 2021

This literature review aims to discuss and collect evidence about restoration techniques of fractured endodontically treated teeth. According to studies in the literature, root canal treatment and restoration of endodontically treated teeth have been reported as two separate clinical procedures although many aspects of both procedures are similar. Conducting restoration procedures following endodontic treatment has been reported to be so important as the first obturation of the root canal, and it has been reported with many advantages and favorable events, including eradication and minimizing the presence of bacteria and microorganisms, which might induce serious complications to the affected teeth. Additionally, the literature review discusses the technique of interim restorations, which has been reported to have favorable advantages and outcomes. However, it should be noted that the process is temporary and definitive restorations must be conducted later on. Also, this research investigates the different substances that should be used with the modality, and the different approaches that were previously reported to restore mature and immature affected teeth. Finally, evidence shows that amalgam-based restorations are becoming inferior to resin composite-based restorations which are also more superior to the stainless-steel crown-based ones. Unifying the guidelines for clinical practice is encouraged to obtain favorable outcomes. All the detailed techniques are presented and fully discussed within the main text of this research.
Life skills education: a coping strategy against substance abuse
Authors: Roy Pritam Kumar , Pydipalli Mounika , Trivedi Shruti , Rehman Waheda , Thakkar Vallabh
Published: July 2021

Substance abuse has been a topic of discussion for healthcare professionals. It involves using harmful or hazardous psychoactive substances that, if administered into one's system, can affect the mental processes. Consumption of these substances leads to societal as well as health problems among its users there by indirectly affecting their families too. These substances mainly include alcohol, tobacco, opiates, cocaine, amphetamines, hallucinogens, prescription and over-the-counter drug abuse.1,2 According to the world drug report 2020 by United Nations Office on Drugs and Crime (UNODC), there are about 35 million people who suffer from drug use disorders and require treatment services globally.2 In India, the substance abuse epidemic in the younger generation has increased rapidly. The crucial factors which lead to these problems involve familial, social as well as individual problems. Familial issues may involve childhood maltreatment or familial substance abuse. Similarly, social issues involves deviant peer pressure and association with popular groups in order to prevent from being bullied. Individual factors which might lead to substance abuse includes depression and attention deficit hyperactivity disorder (ADHD).3 Its prevalence at the national level varies for different substance abuse forms, accompanied by drastic regional variations. Issues regarding treatment access and adherence concerning substance user disorders (SUD) already existed. Due to the current COVID-19 situation, drastic social and economic changes have further worsened the situation. So in this regard, newer strategies have to be brought up in place.4 It has been found that life skills education is one of the most influential activities in school-based substance abuse prevention.
Childhood poisoning causes and prevention; eight years of our rural hospital experience from South India
Authors: Malar Ilango , Dorthy V. , Newtonraj Ariarathinam
Published: July 2021

Poisoning is a significant public health problem, globally as well as in India.1 Poisoning among adults are mostly suicidal whereas among children are accidental in nature.2 In India, childhood poisoning is usually under reported as there is no proper surveillance system is available India and only hospital based data are available.2,3We report our experience from a remote rural hospital from South India after getting institute ethical committee clearance for dissemination of data (Ref no. RC 18/55). We extracted the data of under-five children poisoning cases from poisoning register maintained in the hospital for the period of past eight years from 1st January 2012 to 31st December 2019. Total of 21 childhood poisoning were reported among them 12 (57%) were male and 9 (43%) were female. Most common poisoning was due to kerosene (8(38%)) followed by laundry bleaching detergent locally known as ‘Ala’ 5 (23%), pesticide poison 2 (10%), eucalyptus oil poisoning 2 (10%) and others like ant killer poisoning tablets overdose were 4 (19%).In children, poisoning are accidental nature and the amount consumed may also be less  as the child has tendency for aversion due to smell and taste whereas in suicidal (deliberate poisoning) the dose will be higher to cause permanent damage and death.2 But unlike other poisoning a peculiar finding on reported eucalyptus oil poisoning was, in both cases eucalyptus oil was given to the children to consume as a medicine to cure respiratory tract infection and both of them presented with seizure and unconsciousness. Eucalyptus oil is advice as a topical medicine in the indigenous system of medicine but not as a parenteral medicine.4 In a place like India where there are prevailing false cultural beliefs, there is a need to educate and guide the people on misuse of medicines without proper advice, especially among children. A higher dose of eucalyptus oil poisoning may even result in death.5,6 Another important observation was bleaching detergent poisoning which is not properly reported other major studies from India, but this poisoning is the second most commonest among under-five children.2,3 This poison is an oxidizer and a corrosive in nature and on accidental ingestion may result in minor to transient adverse event with no sequelae in majority of cases.7
Pengaruh Tomat Sambung Pada Intensitas Penyakit Layu Bakteri (Ralstonia solanacearum), Komponen Hasil Produksi, dan Kualitas Buah
Authors: Lisa Navitasari  , Joko Tri , Murti Rudi Hari , Arwiyanto Triwidodo
Published: July 2021

Ralstonia solanacearum (Smith) is one of soil borne pathogens causes bacterial wilt diseases and R. solanacearum is difficult to control because it has a long survival in the soil and have many hosts alternatives. One alternative to control R. solanacearum and to increase productivity is by using grating with combination of resistant varieties of tomato as a rootstock and high production varieties of tomato as a scion. Several studies on grafting to suppress R. solanacearum were reported. However, study on grafting with combination between resistant tomato varieties (Amelia H7996) and high-production tomato varieties with R. solanacearum infestation and without R. solanacearum infestation on the component of yield and fruit quality is limited. The study aims to analyze the effect of grafting with R. solanacearum infestation to the intensity of bacterial wilt disease, component of yield, and fruit quality with R. solanacearum infestation and without R. solanacearum infestation. The result indicated that the intensity of bacterial wilt disease on grafted tomato did not significantly different from resistant rootstock but significantly different from scion.  Infestation of R. solanacearum on grafted tomato can decreased the plant productivity that decreased the component of yield on grafted tomato. R. solanacearum infestation also decreased the fruit quality on diameters and fruit firmness. Nevertheless, R. solanacearum did not affect the Total soluble solid/TSS (°Brix). TSS on grafted tomato indicated that the value is taller than rootstock in the field with R. solanacearum infestation and in the field without R. solanacearum infestation.

 

Keywords: fruit quality, productivity, Rasltonia solanacearum, tomato grafted
STUDY OF STRUCTURAL TRANSFORMATIONS AT INCREASED TEMPERATURES IN α-TITANIUM WITH NON-METALLIC TRACE IMPURITIES
Authors: Kuksenova L. I. , Savenko V. I. , Khasbiullin R. R.
Published: July 2021

Structural changes in α-titanium containing non-metallic trace impurities at elevated temperatures have been studied by differential scanning calorimetry and X-ray diffraction analysis. The microstructural and energy characteristics of structural phase transitions have been determined.
APPLICATION OF IMPACT THEORY TO ANALYSIS OF GEAR SHIFTS IN DUAL-CLUTCH TRANSMISSIONS
Authors: Salamandra K. , Korendyasev G.
Published: July 2021

The article discusses a dynamic model of a transmission containing a dual-clutch gearbox. The absence of a torque converter in such gearboxes, taking into account the short duration of gear shifting (0.2 - 0.5 sec), allows us to present the gear shifting process as an impact. Gear shifting excites the output shaft of the gearbox. Thus, the transmission of the vehicle can beconsidered as a vibro-impact self-oscillating system.
A QUANTITATIVE ANALYSIS OF SOCIAL EFFECTS OF CANCER PATIENTS AND ITS IMPACTS ON QUALITY OF LIFE
Authors: Rehan  , Alam Intikhab , Khan Younas , Hanan Fazal , UrRahman Habib
Published: July 2021

Purpose of the study: The present study explores the social effects of cancer patients and their impacts on their quality of life (QoL).

Methodology: A cross-sectional based study was conducted in district Dir lower from a cancer patient (n=155). A structured questionnaire technique was used for data collection. Descriptive statistics and inferential statistics were carried out for both variables, i.e. dependent variable (QoL) and independent variable (Social effects of cancer patients).

Principal Findings: Among all 155 sampled respondents, 75.5% were male, having 42.6% had age group of 26-40 years, 79.9% were married, 47.1% were literate, and 32.3% were dependent on family members on economic terms. However, the perceptions of cancer patients with regards to social effects of Cancer majority 76.8% were proclaimed that social support decline cancer illness, 71% stated that religious doctrine gives spiritual healings, 70.3% dismantled that after cancer family supports us, 45.2% were reported that Cancer is a fatalistic disease, and 51.6% proclaimed that preference is given to male over a female concerning cancer disease respectively.

Applications of this study: Cancer affects social life, especially domestic affairs; however, this study was not primarily identified cancer diagnoses parameters due to the cross-sectional and perception nature of the study. A longitudinal follow-up study is the order of the day to determine whether there is any link between sociological and Cancer contexts.

Novelty/Originality of this study: This study is an attempt to insight into the sociological exploration of cancer patients effects through perceptional based research methodology/ Likert Scale procedure along with quantitative research design to measure the association between the aforementioned variable above with an amalgamation of an addition in the field of medical sociology.
BENEFÍCIOS DO MÉTODO CANGURU PARA O ALEITAMENTO MATERNO
Authors: Silva Roselaine Nascimento da , Cechetto Fátima Helena , Riegel Fernando
Published: July 2021

Objetivo: verificar os benefícios do Método Canguru para o aleitamento materno. Método: revisão Integrativa, por meio das bases de dados SciELO, BDENF e LILACS, os dados foram coletados entre os meses de agosto de 2018 e maio de 2019. Para a análise dos dados obtidos foi utilizada a análise de conteúdo. Resultados e Discussão: os benefícios do Método Canguru para o aleitamento materno encontrados estão relacionados com o aleitamento materno como fator de promoção, maior adesão e manutenção do aleitamento materno, redução do desmame precoce, melhor sucção, e maior produção de leite. Considerações finais: formas indiretas relacionadas ao método Canguru envolvendo o aleitamento materno foram identificados: o aumento de peso do recém nascido, redução do tempo de internação do recém nascido, favorecimento da construção do vínculo mãe-bebê e contribuição para o desenvolvimento global.Descritores: Política pública; Enfermagem; Método Canguru; Aleitamento materno.
Comparison of Light Transmission Aggregometry and VerifyNow in Detecting Clopidogrel Resistance and Factors Affecting Clopidogrel Resistance in AMI-EST Patients Undergoing Percutaneous Coronary Intervention: A Cross-Sectional Study
Authors: Giantini Astuti , Timan Ina Susianti , Listiyaningsih Erlin , Dharma Rahajuningsih , Setiabudy Rianto , Alwi Idrus , Partakusuma Lia Gardenia , Indrasari Nuri Dyah , Harahap Alida Roswita , Suparmin Siskawati , Sahar Windy , Sukmawan Renan
Published: July 2021

BACKGROUND: Light transmission aggregometry (LTA) and VerifyNow is commonly used to measure platelet responsiveness to clopidogrel. This study aimed to compare the results of LTA and VerifyNow P2Y12 assay for assessing the clopidogrel resistance in patients undergoing percutaneous coronary intervention and determine factors affecting clopidogrel resistance.METHODS: The subjects were 119 patients who underwent percutaneous coronary intervention (PCI) and had given loading dose of 600 mg clopidogrel. Blood samples were taken at 6 hour after clopidogrel loading dose. Platelet aggregation was measured by LTA and VerifyNow.RESULTS: LTA and VerifyNow assay showed fair agreement with Kappa=0.270, p=0.001. The proportion of resistance to clopidogrel using VerifyNow was 21.8% and LTA was 47.1%. Patients with diabetes melitus were more likely to develop clopidogrel resistance than patients without diabetes (OR of 7.67; 95% CI: 1.87-31.50; p=0.005).CONCLUSION: The ability of LTA and VerifyNow in detecting clopidogrel resistance were not comparable. Multivariate analysis results for VerifyNow shows diabetes mellitus as the greatest predictors of clopidogrel resistance.KEYWORDS: agreement, clopidogrel resistance, LTA, predictor, VerifyNow
Metformin Reduced Collagen Deposition and Contractility, but Increased Collagen Degradation in in vitro Posterior Capsule Opacification Model
Authors: Brilliyanto Frisma Sagara , Suhendro Gatut , Wahyuni Indri , Rochmanti Maftucah , Pramono Windhu
Published: July 2021

BACKGROUND: Posterior capsule opacification (PCO) often occurs after cataract surgery. Metformin has been known to have an ability to inhibit fibrosis. This study aimed to investigate the effects of metformin on cell contractility, collagen deposition and degradation in human lens epithelial cells (HLEC) of cataract patients.METHODS: HLEC were isolated from the anterior lens capsule of patients undergoing cataract surgery. The HLEC culture was carried out using explant culture technique. The in vitro PCO model was created by scratching technique on HLEC cultures. The treatment groups were given 0.1, 0.5 and 1 mM metformin, respectively, while the control group were given 10% fetal bovine serum (FBS). On the 7th day after scratching technique, the collagen deposition, collagen degradation and cell contractility were evaluated.RESULTS: Collagen deposition in HLEC was significantly reduced after given 0.1 mM, 0.5 mM and 1 mM metformin (17.92±6.16 mg/mL, 12.92±4.31 mg/mL, 11.25±5.30 mg/mL, respectively), compared to the control group (31.46±7.52 μg/mL, p=0.002). Collagen degradation significantly was increased in the 0.1 mM, 0.5 mM and 1 mM metformin groups (4.77±9.27 mg/mL, 6.59±1.16 mg/mL, 6.35±1.90 mg/mL, respectively) compared to the control group (2.21±2.78 μg/mL, p=0.002). While, collagen contractility in HLEC was significantly reduced in 0.1mM, 0.5mM and 1 mM metformin groups (16.39±3.89%, 13.89±2.59%, 11.93±2.44%, respectively), compared to the control group (44.25±4.95%, p=0.000).CONCLUSION: Metformin reduced collagen deposition and contractility, but increased collagen degradation in HLEC of cataract patients through mechanism of extracellular matrix remodeling.KEYWORDS: metformin, human lens epithelial cell, fibrosis
​Erythrocyte Parameters as a Diagnostic Tool in Canine Medicine: A Review
Authors: Yadav S.N. , Ahmed N. , Nath A.J. , Boro P.K.
Published: July 2021

The haematological analysis is one of the essential diagnostic and prognostic tools for the health practitioner. Routine hematology consists of erythrocyte, leucocyte and platelet parameters estimation. Erythrocyte parameters (RBC, RDW, haemoglobin, haematocrit, MCV, MCH, MCHC) estimation plays a crucial role in identifying anemia and several other acute and chronic conditions. Accurate and precise haematology results depend on correct blood collection procedures, suitable anticoagulants, proper storage and effective blood transport. The individual reference value variance can be due to age, sex, stress, diet, body condition, hydration status and reproductive status. Automatic haeamtology analyzer can yield quick and accurate results provided the sample is free from any artifacts. In conclusion, the accuracy of the result of automatic haematology analyzer in canine medicine is impeded by the lack of precise and rapid comparison procedure, instability and complexity of blood cells. Therefore the findings of the automatic haemotolyzer should always be corroborated with the clinical findings and another laboratory test.
​Effect of Nutrients on Wilt in Chickpea
Authors: Nathawat B.D.S. , Sharma O.P. , Kumari Manju , Shivran Hansraj
Published: July 2021

Background: Chickpea (Cicer arietinum L.) contributes 18% of the global production of grain legume and serves as an important source of dietary protein. Fusarium wilt, caused by soil borne fungus Fusarium oxysporum f. sp. ciceri appears to be the most devastating diseases of chickpea throughout the world. It is one of the important limiting factors of chickpea production in India. The disease causes substantial yield losses which may reach even 100 per cent under favorable weather conditions. Methods: Pot culture experiments were conducted at Rajasthan Agricultural Research Institute, Durgapura, Jaipur during rabi 2014-15 and 2015-16 to study the effect of nutrients on wilt caused by Fusarium oxysporum f. sp. ciceri (Padwick) in chickpea (Cicer arirtinum). In the first experiment, the treatments comprised of four nitrogen levels-viz. 0, 15, 20 and 25 kg/ha and four phosphorus levels- viz. 0, 30, 40 and 50 kg/ha tried in sixteen treatment combinations. Surface sterilized seeds of chickpea cultivar L-550 were sown in each pot. After sowing, 400 ml water was supplied to each pot; there after watering was done at an interval of 6 days. In second experiment, the treatments comprised of 7 micronutrients viz. zinc, manganese, calcium, copper, cobalt, iron and nickel used at the rate of 10mg/kg of soil. Chickpea cultivar L-550 was used as a test crop. Result: Disease incidence was recorded periodically commencing 15 days after sowing and was continued up to 55 days after sowing. Levels of nitrogen application had increased wilt incidence successively in both the years. Whereas, a reverse trend was observed with the application of phosphorus, incidence of wilt was decreased with increasing levels of phosphorus. Application of zinc and calcium reduced the wilt incidence significantly over check. Zinc was found to be most effective in minimizing the disease incidence.
Harvesting and Threshing Methods on Seed Quality of Dhaincha (Sesbania aculeata)
Authors: Masilamani P. , Eevera T. , Ramesh T. , Venkatesan S.
Published: July 2021

Background: The present investigation is an attempt to study the effect of different harvesting and threshing methods on germination and seedling vigour of dhaincha. The use of a combine harvester to harvest dhaincha will be an effective alternative method that has not been widely tried. However, work on different methods of harvesting and threshing of dhaincha is limited. Hence, a study was conducted to evaluate the impact of various harvesting and threshing methods on germination and seedling vigour of dhaincha. Methods: This study was conducted at Anbil Dharmalingam Agricultural College and Research Institute, TNAU, Tiruchirappalli, Tamil Nadu. The dhaincha crop was harvested and threshed using four different methods viz., manual harvesting and manual threshing, manual harvesting and threshing by tractor treading, manual harvesting and mechanical threshing and harvesting and threshing by combine harvester. The resultant seeds were tested for mechanical damage and germination potential. The experiment was laid in completely randomized block design. Germination was tested by roll towel method using 100 seeds in four replications. Germination percentage, root and shoot length were measured in seven days after sowing from ten randomly selected seedlings in each replication. For the estimation of dry matter production, ten seedlings were selected at random and kept in a hot air oven maintained at 85oC for 24 hours after measuring their root and shoot length and vigour index was calculated. Mechanical damage to seeds was observed by ferric chloride test. Seed recovery per cent was calculated based on the 100 kgs of dhaincha seeds were cleaned and graded treatment wise using cleaner cum grader and the seeds retained on the bottom sieve were weighed and expressed as per cent of total quantity of seed. Result: The results revealed that the significant difference was found among the different harvesting and threshing methods. The seeds harvested and threshed by manual method recorded 85 per cent germination followed by seeds harvested manually and threshed by mechanical threshing (84 per cent) and seeds harvested manually and threshed by tractor treading (80.5 per cent). The lowest germination of 80.0 per cent was recorded by combine harvesting. From this study, it could be inferred that combine harvester is a modern method for harvesting of dhaincha that saves time and labour when compared to all other methods.
Estudio experimental del efecto en el comportamiento mecánico al adicionar caucho triturado en un suelo arcilloso de baja plasticidad proveniente del caserío de Callampampa - Llama–Cajamarca
Authors:   , Alvarez Benites Nicols Cristina , Gutierrez Gallegos Julio Alvaro
Published: July 2021

La presente investigación presenta la influencia en el comportamiento mecánico de un suelo proveniente del Caserío de Callampampa, Llama, Cajamarca al adicionar caucho triturado. Este suelo es arcilloso de baja plasticidad y sus parámetros físicos fueron determinados con los ensayos, tales como Análisis Granulométrico por medio del Hidrómetro (MTC E 109 -2016) y por Tamizado (MTC E 107 -2016, NTP 339.128) y la determinación del Límite Liquido, Límite Plástico e Índice de Plasticidad (NTP 339.129). El ensayo de Proctor Modificado (NTP 339.141), Corte Directo (NTP 339.171) se realizó como parte de la metodología con el fin de conocer los parámetros mecánicos de las muestras y explicar la influencia que causa el caucho triturado en la resistencia al esfuerzo de corte, la cohesión, ángulo de fricción, etc. Las muestras ensayadas fueron la del suelo natural (S100) y las mezclas con adición de caucho triturado en un 0.5%, 1.5%, 2.5% y 3.5%. Los resultados obtenidos indican que la densidad seca máxima que ofrece la mezcla adicionada con 3.5% de caucho triturado (S100/C3.5) se incrementa en un 1.76%, el contenido de humedad óptimo disminuye en un 5.75%, la resistencia al esfuerzo de corte se incrementa en un 35.2%, la cohesión aumenta en un 64% y el ángulo de fricción disminuye en un 9.1% respecto a la muestra S100. Por otro lado, para el ensayo de CBR (NTP 339.145) se tomó en cuenta los resultados obtenidos en los ensayos de Proctor Modificado para hallar los parámetros del suelo al esfuerzo de penetración y ver la viabilidad como terreno para una subrasante. Los porcentajes fueron 1.5%, 2.5% y 3.5% cuyos resultados son comparados respecto al suelo natural (S100). Los resultados obtenidos a 2mm de penetración con un 95% de M.D.S fue para un S100 de 3.3% y con la mezcla de S100/C3.5 se incrementa a 9.4%. En conclusión, el suelo arcilloso de baja plasticidad mejora sus propiedades mecánicas cuando se le adiciona caucho triturado.
Propuesta para reducir los costos de la no calidad en las partidas de concreto armado utilizando los lineamientos del PMBOK en proyectos de edificación en pequeñas y medianas empresas en la ciudad de Lima
Authors:   , Gudiel Cairampoma Roger Antonio , Solis Puente Noel Percy
Published: July 2021

Casi siempre al hablar de calidad, se relaciona a un producto con un costo por arriba del promedio, esto está en función al mercado en que se ofrezca el producto; para dar un breve alcance de calidad, se puede decir que es la medición de la satisfacción del cliente. Para llegar el objetivo de la entrega del producto final en la construcción, se ejecutan distintas partidas, consideradas en el presupuesto, así como, en el cronograma de obra; estos están sujetos a ciertos controles, los cuales, al no lograr la aprobación, adquieren el nombre de No Conformidad, lo que quiere decir No Calidad. En nuestro medio se han visto emerger grandes, pequeñas y medianas empresas dedicadas al rubro de la construcción de edificaciones comerciales y multifamiliares; muchas de las cuales no contemplan un adecuado sistema de gestión de la calidad; la presente investigación presenta algunos casos de pequeñas empresas que no le dan la importancia adecuada al control de calidad en las partidas de concreto armado; notándose el incremento de los costos propuestos en la etapa de planeamiento. Se analizará cada proyecto, a fin de alcanzar una propuesta, utilizando las herramientas del PMBOK, las cuales permitirán establecer avances en el sistema de gestión de la calidad de cada empresa, logrando así, una mejora continua en sus procesos; los cuales serán elementos medibles a través de criterios básicos y en formatos fáciles de interpretar, logrando así, minimizar los costos de No Calidad y mejoras en los tiempos de ejecución del proyecto.
El sistema de facturación electrónica y su impacto en la gestión contable de las micro y pequeñas empresas del sector comercio del distrito de La Victoria en los años 2018 y 2019
Authors:   , Ayllón García Pacheco Karen , Talledo Calderón Stefanny Rocío
Published: July 2021

El presente trabajo de investigación tiene como propósito evaluar el impacto en la gestión contable que tiene la implementación del sistema de Facturación Electrónica, a partir de su aplicación y evaluación en las micro y pequeñas empresas del distrito de La Victoria en los años 2018 y 2019. El desarrollo de esta investigación está constituido por cinco capítulos. El primer capítulo, es el marco teórico, en donde se definen las bases teóricas de la facturación electrónica y la gestión contable para un mejor entendimiento, adicionalmente se exhibe la situación del sector comercio en Lima Metropolitana. El segundo capítulo, es nombrado el plan de investigación, aquí se plantea el problema principal, los objetivos e hipótesis principales y específicas. Luego en el tercer capítulo llamado metodología de la investigación, se consiguió obtener opiniones relevantes de expertos/gurús en el tema, tanto sobre la facturación electrónica como de la gestión contable; y también opiniones de algunos participantes que trabajan o cuentan con experiencia en el sector comercio, por medio de entrevistas y encuestas realizadas a profundidad. Así pues, en el cuarto capítulo, denominado desarrollo de la investigación, se obtienen los resultados de las entrevistas y encuestas realizadas. Finalmente, en el quinto capítulo, se procede a realizar el análisis de los resultados, validar las hipótesis y conocer el impacto de las variables, teniendo como cierre las conclusiones y recomendaciones que contribuirán a este tipo de empresas del sector comercio, con la finalidad de que reconozcan como puede mejorar su gestión contable a partir de esta implementación.
A New Hybrid Optimizer for Global Optimization Based on a Comparative Study Remarks of Classical Gradient Descent Variants
Authors: Touarsi Mouad , Driss Gretete  , Abdelmajid Elouadi
Published: July 2021

In this paper, we present an empirical comparison of some Gradient Descent variants used to solve globaloptimization problems for large search domains. The aim is to identify which one of them is more suitable for solving an optimization problem regardless of the features of the used test function. Five variants of Gradient Descent were implemented in the R language and tested on a benchmark of five test functions. We proved the dependence between the choice of the variant and the obtained performances using the khi-2 test in a sample of 120 experiments. Those test functions vary on convexity, the number of local minima, and are classified according to some criteria. We had chosen a range of values for each algorithm parameter. Results are compared in terms of accuracy and convergence speed. Based on the obtained results,we defined the priority of usage for those variants and we contributed by a new hybrid optimizer. The new optimizer is testedin a benchmark of well-known test functions and two real applications are proposed. Except for the classical gradient descent algorithm, only stochastic versions of those variants are considered in this paper.
Similarity Technique Effectiveness of Optimized Fuzzy C-means Clustering Based on Fuzzy Support Vector Machine for Noisy Data
Authors: Khanali Hoda , Vaziri Babak
Published: July 2021

Fuzzy VIKOR C-means (FVCM) is a kind of unsupervised fuzzy clustering algorithm that improves the accuracyand computational speed of Fuzzy C-means (FCM). So it reduces the sensitivity to noisy and outlier data, and enhances performance and quality of clusters. Since FVCM allocates some data to a specific cluster based on similarity technique, reducing the effect of noisy data increases the quality of the clusters. This paper presents a new approach to the accurate location of noisy data to the clusters overcoming the constraints of noisy points through fuzzy support vector machine (FSVM), called FVCM-FSVM, so that at each stage samples with a high degree of membership are selected for training in the classification of FSVM. Then, the labels of the remaining samples are predicted so the process continues until the convergence of the FVCM-FSVM. The results of the numerical experiments showed the proposed approach has better performance than FVCM. Of course, it greatly achieves high accuracy.
GH Biplot in Reduced-Rank Regression based on Partial Least Squares
Authors: Alvarez Wilin , Griffin Victor John
Published: July 2021

One of the challenges facing statisticians is to provide tools to enable researchers to interpret and present their data and conclusions in ways easily understood by the scientific community. One of the tools available for this purpose is a multivariate graphical representation called reduced rank regression biplot. This biplot describes how to construct a graphical representation in nonsymmetric contexts such as approximations by least squares in multivariate linear regression models of reduced rank. However multicollinearity invalidates the interpretation of a regression coefficient as the conditional effect of a regressor, given the values of the other regressors, and hence makes biplots of regression coefficients useless. So it was, in the search to overcome this problem, Alvarez and Griffin  presented a procedure for coefficient estimation in a multivariate regression model of reduced rank in the presence of multicollinearity based on PLS (Partial Least Squares) and generalized singular value decomposition. Based on these same procedures, a biplot construction is now presented for a multivariate regression model of reduced rank in the presence of multicollinearity. This procedure, called PLSSVD GH biplot, provides a useful data analysis tool which allows the visual appraisal of the structure of the dependent and independent variables. This paper defines the procedure and shows several of its properties. It also provides an implementation of the routines in R and presents a real life application involving data from the FAO food database to illustrate the procedure and its properties.
Nonpreemptive Goal Programing Method in Optimization Nurse Scheduling by Considering Education Level
Authors: Utina Fitriani , Yahya Lailany , Nurwan Nurwan
Published: July 2021

Nurse scheduling is one of the problems that often arise in hospital management systems. Head of ICU room and nurse to cooperate in making good nurse scheduling for the creation of optimal service. In this paper, we study a hospital nurse schedule design by considering the level of nurse education and the provision of holidays. Nurses with undergraduate education (S1) Nurses become leaders on every shift and are accompanied by nurses with diploma education (D3). The scheduling model in this study using the nonpreemptive goal programming method and LINGO 11.0 software. The preparation of the schedule of nurses assigned to this method can optimize the need for efficient nurses per shift based on education level. The data in the research was obtained by collecting administrative data at Aloei Saboe Gorontalo hospital. The data used are the published schedule by the head of the ICU room. In making a nurse schedule, there are limitations to consider such ashospital regulation. The results of the study obtained an optimal solution in the form of meeting all the desired obstacles. Computational results shows that nurse scheduling using the nonpreemptive goal programming method and LINGO 11.0 software better than the schedule created manually. Every shift is a maximum of one leader with an undergraduate education (S1) background and accompanied by a nurse with a diploma education (D3) background. Keywords: scheduling, goal programming, nonpreemptive goal programming.
Effect of Macronutrient Combination on Survivorship, Growth, and Nutritional Content of Black Soldier Fly Larvae (Hermetia illucens)
Authors: Sari Anggraeni Arum , Kinasih Ida , Sari Dian Anggria , Putra Ramadhani Eka
Published: July 2021

Larvae of black soldier fly (Hermetia illucens) has been widely applied as a biological agent for biodegradable wastes upcycling through bioconversion process. However, most of the biodegradable wastes produced from economic activities other than industrial is heterogenous. This may cause some physiological change which may alter the survivorship, growth, and efficiency of the bioconversion process. In this study, the substrate combination of macronutrients provided to black soldier fly larvae were observed to understand the larvae ability to degrade organic waste from economic activities. The substrat proportion consist of three major macronutrients (carbohydrate, protein, and lipid) and made of a mixture of decayed cabbage (Brassica oleracea) (source of carbohydrate), shark catfish (Pangasius sp.) (source of protein), and avocado (Persea americana) (source of lipid) which consisted of four types of substrate namely high fiber, high protein, high lipid, and balance. The feeding rate was 100 mg/larvae/day which provides every three days until 50% of larvae metamorphosed into prepupae. Mortality rate, the weight of larvae, and weight of residue (undigested substrate) were measured during substrate replacement and used to calculated survivorship rate, ECD (Efficiency of Conversion Digested-feed), AD (Approximate digestibility), and WRI (Waste Reduction Index). The proximate analysis also conducted on the harvested larvae biomass. The larvae group fed on high protein substrate showed best survivorship (64,75±2,60%), growth rate (2,97±0,166 mg/larvae/day), and AD (57,39±3,39) while the highest WRI recorded for larvae group fed on high fiber substrate and the highest ECD recorded for larvae group fed on high lipid substrate. The proximate analysis showed the best nutritional content of prepupae of larvae group fed on high protein substrate. It can be concluded that the proportion of macronutrients of substrate effect the growth and bioconversion performance of black soldier fly larvae. Some strategies related to the optimization of the bioconversion process for heterogeny substrate are discussed.Keywords: biodegradable wastes, black soldier fly, heterogeneity, growth, nutritional content, survivorship.
Kluwek Seed (Pangium edule Reinw) Germination Response to Soaking Time and Concentration of Gibberellin Acid (GA3)
Authors: Ratnasari Tri , Ana Daniar Alfi , Sulistiyowati Hari , Setyati Dwi
Published: July 2021

Kluwek seeds (Pangium edule Reinw.) have a low germination percentage caused by dormancy due to hard seed coat. Kluwek seed germination takes about 1 month. The purpose of this study was to obtain a combination of treatments that were effective in increasing the percentage of kluwek seed germination and reducing the intensity of kluwek seed dormancy. This study used a Completely Randomized Design (CRD) factorial design. The first factor was immersion time (H) consisting of five levels, namely H0: Control (0 hour), H1: 6 hours, H2: 12 hours, H3: 18 hours, and H4: 24 hours and the second factor was giberellin concentration (G) with five levels namely G0: 0 ppm, G1: 25 ppm, G2: 50 ppm, G3: 75 ppm and G4: 100 ppm. Data analysis used Analysis of Variance (Anava) and further tested with Duncans' Multiple Range test (DMRT) at a significant level of 5%. The results obtained showed that the percentage of seed germination without immersion is 6.67%. Soaking using aquades produces an average germination percentage of 28.33%. The most effective treatment was GA3 75 ppm for 24 hours with seed germination of 60%, while the value of dormant intensity is 40%.Keywords: dormancy, germination, gibberellin, kluwek.
Molecular-genetic mechanisms of the signal cascade RAS-RAF-MEK-ERK associated with the development of the tumor process and the purpose of targeted drugs for colorectal cancer
Authors: Toropovsky A. N. , Pavlova O. N. , Viktorov D. A. , Nikitin A. G.
Published: July 2021

Colorectal cancer occupies one of the leading positions in the world in the structure of cancer incidence. The vital processes of cancer cells largely depend on the production of growth factors and their receptors. One of these is epidermal growth factor (EGFR), which is a tyrosine kinase receptor for cell membranes. Normally, binding of EGFR ligands and transforming growth factor alpha (TGFα) induces receptor activation, which triggers ERK and PI3K signaling pathways that control cell proliferation, migration, invasion, and many other processes. It was found that in 80% of cases, colorectal cancer occurs as a result of EGFR overexpression, which leads to increased growth and division of tumor cells due to hyperactivation of the RAS-RAF-MEKERK signaling cascade. The RAS-RAF-MEK-ERK cascade is a pathway that regulates cell proliferation, cell cycle, and cell migration. In the development of human cancer, mutations of the RAS/RAF family are most often the cause of dysregulation of signal transduction through this pathway. According to current data, about a third of all malignant neoplasms are associated with mutations in the genes of the RAS family, which include HRAS, KRAS, NRAS, RRAS, and other homologous proteins. Proteins of the RAS family are involved in the activation of tyrosine kinase signaling pathways, which leads to gene mutations. This process determines proliferative activity, ability to differentiate, metastasis, avoidance of apoptosis, induction of angiogenesis. Permanent RAS activation leads to malignant cell degeneration. Thus, the expression and mutation of the EGFR gene are associated with various variants of tumor progression and poor prognosis in malignant neoplasms of various localizations. Over the past decades, significant advances have been made in the treatment of metastatic colorectal cancer. However, the expansion of the spectrum of effective anticancer drugs also creates a number of difficulties in choosing the optimal drug therapy regimens in patients with metastases of colorectal cancer.
Ciclo económico y performance de la combinación de las estrategias de diversificación de producto y expansión internacional
Authors: Guerras-Martín Luis Ángel , Zúñiga-Vicente José Ángel , Benito-Osorio Diana , Colino Alberto
Published: July 2021

Se analiza el efecto conjunto de las estrategias de diversificación e internacionalización sobre los resultados empresariales teniendo en cuenta el ciclo económico, en las empresas manufactureras españolas entre 1994-2014. En dicho período, la economía española experimentó un elevado crecimiento económico (1994-2008), seguido de una profunda crisis (2009-2014). Nuestro estudio revela que ambas estrategias conducen a mejores resultados en la etapa de crecimiento cuando la internacionalización se combina con niveles moderados de diversificación relacionada. Cuando optan por altos niveles de diversificación no relacionada, la combinación con la estrategia de internacionalización solo lleva a mejores resultados en la etapa de crecimiento.
Colaborar con socios internacionales para innovar: implicaciones para empresas de servicios profesionales y tecnológicos
Authors: Nieto María Jesús , Rodríguez Alicia , Santamaria Luis
Published: July 2021

Las empresas de servicios intensivos en conocimiento juegan un papel fundamental como intermediarios y generadores de conocimiento en la economía actual. La comprensión, por tanto, de cómo estas empresas desarrollan innovaciones es de suma importancia. Entre las estrategias que contribuyen al desarrollo de innovaciones en estas empresas analizamos las colaboraciones tecnológicas. En este artículo resumimos las implicaciones de las colaboraciones internacionales para las empresas de servicios intensivos en conocimiento, diferenciando entre las de carácter profesional y las tecnológicas. Se tiene en cuenta la diversidad y la proximidad de los socios en la colaboración.
Dampak Corona Virus Diseases (Covid 19) Terhadap Kinerja Pustakawan (Study Pada UPT. Perpustakaan Universitas Trunojoyo Madura)
Authors: Arief Murnia , Ismail Iriani
Published: July 2021

Semenjak mulai diumumkannya pandemi coronavirus diseases (Covid 19)di Indonesia pada awal bulan Maret 2020, pemerintah sudah mulai berupaya meningkatkan penanganan  pandemi global Covid-19 ini. UPT. Perpustakaan UTM menerapkan WFH sebagai pilihan untuk antisipasi penularan Covid19, sesuai dengan surat edaran Rektor. Tentunya WFH adalah pilihan sulit bagi pustakawan, karena merupakan hal baru diluar kebiasaan, ada beberapa kendala yang ditemukan selama pelaksaan WFH, tetapi semua dapat diatasi dengan komunikasi yang intens antara pustakawan yang WFH dengan pimpinan, serta aturan yang jelas yang telah disepakati dari awal, dengan begitu penerapan WFH berjalan dengan lancar dan pustakawan dapat menghasilkan kinerja yang maksimal sehingga fungsi perpustakaan sebagai penyedia sumber informasi dapat tetap berjalan dalam situasi pandemi ini. Penelitian ini menggunakan metode kualitatif interaktif dengan pendekatan studi kasus.
FLUKTUASI SAHAM SYARIAH DI INDONESIA SAAT PANDEMI COVID-19 AKIBAT PERUBAHAN VARIABEL MAKROEKONOMI: ANALISIS PADA SUB SEKTOR HOTEL, RESTAURANT DAN PARIWISATA
Authors: Mutohharo Naji Hatul , Nurhayati Putri
Published: July 2021

ABSTRAKPandemi COVID-19 merebak dengan cepat keseluruh negara di dunia menimbulkan banyak dampak termasuk dalam bidang perekonomian. Adanya kebijakan-kebijakan khusus untuk mencegah penyebaran virus, seperti pembatasan mobilisasi dan kegiatan public memberikan dampak yang cukup masif, termasuk pada bidang pariwisata. Penelitian ini bertujuan untuk melihat pengaruh beberapa variabel makro, berupa nilai tukar, IHSG, Dow Jones Index (DJI), Dow Jones Islamic Market Index (DJIMI), dan harga minyak dunia terhadap fluktuasi harga saham perusahaan sub sektor hotel, restoran, dan pariwisata yang terdaftar dalam Indeks Saham Syariah Indonesia. Menggunakan metode Partial Least Square (PLS), menunjukkan hasil sepanjang 2 Maret hingga 30 September 2020, nilai tukar dan IHSG berpengaruh positif signifikan terhadap harga saham, sedangkan harga minyak berpengaruh tidak signifikan. DJI berpengaruh negatif tidak signifikan terhadap harga saham sedangkan DJIMI berpengaruh negatif signifikan. Sepanjang pandemi dapat dimungkinkan banyak variabel makro maupun mikro yang mengalami goncangan dan turut memberi pengaruh terhadap harga saham pada sub sektor hotel, restaurant dan pariwisata.Kata Kunci: Dow Jones Index, Dow Jones Islamic Market Index, Harga Minyak, IHSG, Nilai Tukar. ABSTRACTThe COVID-19 pandemic, which spreads rapidly around the world, has raised many impacts, including in economic sector. There are particular policies to prevent the spreading of COVID-19 virus, such as restrictions of mobilization and public activities which give some massive impacts, including the tourism sector. This study aims to see the impact of several macroeconomic variables, those are exchange rate, IHSG, Dow Jones Index (DJI), Dow Jones Islamic Market Index (DJIMI), and world oil price, due stock price fluctuations in the hotel, restaurant and tourism sub-sector companies listed on Indonesia Sharia Stock Index. Using Partial Least Square (PLS) method, it shows the results from March 2 to September 30 2020, exchange rate and IHSG have positive significant effect on stock price, while oil price has no significant effect. DJI has a negative and insignificant effect on stock price, while DJIMI has a negative significant effect. Through this pandemic, there are many macro or micro variables may experience shocks and give some contribution to the effect of sharia stock price in the hotel, restaurant and tourism sub-sector.Keywords: Dow Jones Index, Dow Jones Islamic Market Index, Exchange Rate, IHSG, Oil Price.
PENGARUH SOURCE OF FASHION KNOWLEDGE DAN FASHION CONSCIOUSNESS TERHADAP HIJAB FASHION PURCHASE INTENTION PADA MAHASISWI MUSLIM DI SURABAYA
Authors: Aristawati Qoidah Weka , Prasetyo Ari
Published: July 2021

ABSTRAKWanita muslim saat ini lebih sadar akan citra diri dan identitas sosial mereka, dan kesadaran ini mempengaruhi konsumsi mereka termasuk hijab fashion. Dalam niat pembelian produk hijab fashion,sumber informasi tentang fashion hijab dan kesadaran seorang muslim menjadi faktor penting. Mahasiswi muslimah mencari informasi tentang fashion hijab yang sedang trend saat ini dari relasi, media sosial maupun media cetak. Penelitian ini bertujuan untuk menganalisis source of fashion knowledge dan fashion consciousness terhadap hijab fashion purchase intention mahasiswi muslim di Surabaya. Penelitian ini melibatkan 140 mahasiswi yang mengenakan hijab di 16 perguruan tinggi di Surabaya. Hasil penelitian ini menunjukkan bahwa source of fashion knowledge dan fashion consciousness berpengaruh signifikan terhadap hijab purchase intention. Kata Kunci: Hijab, Fashion, Fashion Consciousness, Hijab Purchase Intention, Source of fashion knowledge, mahasiswa muslimah surabaya. ABSTRACTToday's Muslim women are more aware of their self-image and social identity, and this awareness affects their consumption including hijab fashion. In the intention of purchasing hijab fashion products, sources of information about hijab fashion and the awareness of a Muslim are important factors. Muslim female students seek information about the current trend of hijab fashion from relationships, social media and print media. This study aims to analyze the source of fashion knowledge and fashion consciousness on the hijab fashion purchase intention of Muslim students in Surabaya. This study involved 140 female students who wore the hijab at 16 universities in Surabaya. The results of this study indicate that the source of fashion knowledge and fashion consciousness has a significant effect on hijab purchase intention.Keywords: Hijab, Fashion, Fashion Consciousness, Hijab Purchase Intention, Source of fashion knowledge, Muslimah Surabaya students.