bluuebunny/crossref_metadata_2025 huggingface dataset:
Frost measurement of air source heat pump heat exchangers based on image recognition processing technology
Authors: Chen Liming , Xie Bin
Published: April 2024

In order to understand the application of frost measurement of air source
heat pump heat exchanger, a research on frost measurement of air source heat
pump heat exchanger based on image recognition processing technology is put
forward. In this paper, the scheme design of defrosting control system based
on image processing technology is introduced, and the frost degree
coefficient of outdoor heat exchanger fin surface is introduced to
characterize the frost degree of fin surface. Secondly, the experimental
environment room was built, and the conventional defrosting control method
of the existing heat pump unit was tested on the spot. It was found that in
the air temperature of -6~0?C and the air relative humidity of 86~92%, the
unit appeared the phenomenon of ?defrosting in time? and ?defrosting
without frost?. Finally, the change of frost layer on the surface of the
outdoor heat exchanger fin during defrosting is analyzed, and the
coefficient of frost degree on the surface of the fin is calculated and
analyzed. At the beginning of defrosting, due to the large degree of frost,
the P-value of the frost degree coefficient on the surface of the fin is
close to 1, when the defrosting is carried out for 125 seconds, the P-value
of the frost degree coefficient on the surface of the fin decreases sharply
to 0.09, when the defrosting is completed, the P-value of the frost degree
coefficient on the surface of the outdoor heat exchanger is maintained at
about 0.04. The defrosting control method of air source heat pump based on
image processing technology is proposed in this paper, and its technical
feasibility and effect are verified by experimental tests, which lays a
foundation for future popularization and application.
Multi-objective particle swarm optimization algorithm for data acquisition and system characteristics research of phase change thermal storage heat pump water heaters
Authors: Cheng Chuanxu , Yang Nan
Published: April 2024

In order to understand the multi-objective particle swarm optimization algorithm for data collection and system characteristics research of heat pump water heaters, the author proposes a multi-objective particle swarm optimization algorithm for data collection and system characteristics research of phase change thermal storage heat pump water heaters. The author first introduced the working principle of the phase change heat storage heat pump water heater, and then conducted a comparative experimental study on the performance of two types of heat pump water heater systems using pure paraffin phase change heat storage and water storage. They compared and analyzed the heat storage process, condensation heat recovery rate of the heat storage box, and comprehensive energy efficiency coefficient of the system under the refrigeration and heat recovery mode of the two types of heat pump water heater systems, on this basis, measures were proposed to improve the performance of pure paraffin phase change thermal storage hot water systems. At long last, the examination of exploratory information shows that the Rx of the water warm capacity framework is around 6% higher than that of the stage change warm capacity framework, and the framework COPt is likewise 20% higher than that of the stage change warm capacity framework, from this, it tends to be seen that the stage change heat capacity box has unfortunate intensity move proficiency, prompting a lessening in the presentation of the intensity siphon water radiator framework. Contrasted and customary water stockpiling heat siphon boiling water frameworks, unadulterated paraffin stage change capacity heat siphon high temp water frameworks lessen the volume of the intensity stockpiling tank, and the framework works somewhat flawlessly during the intensity stockpiling process. However, the system?s overall energy efficiency is impacted by the heat storage tank?s poor heat exchange effect and relatively low condensation heat recovery rate. The intensity move of the intensity stockpiling box can be upgraded by finning the winding curls in the intensity stockpiling box, embedding aluminum foil, adding extended graphite, and different measures to further develop the buildup heat recuperation rate, subsequently working on the general execution of the framework.
Estratégias Práticas para a Curricularização da Extensão
Authors: Marques Gleicy Corrêa Nunes , Stallivieri Luciane
Published: April 2024

A extensão apresenta-se em um contexto de mudanças de diretrizes e concepções com a chegada da Resolução CNE/CES n.º 7/2018, pela qual foram exigidas mudanças institucionais até dezembro de 2021. Este artigo tem como objetivo apresentar estratégias práticas para a curricularização da extensão dos cursos de graduação do Instituto Federal de Educação, Ciência e Tecnologia de Santa Catarina, tendo como base a identificação de pontos positivos e negativos da curricularização dessa instituição. O referencial teórico está fundamentado em gestão universitária, extensão e currículo. A pesquisa é de natureza aplicada, descritiva, um estudo de caso de abordagem qualitativa. Percebeu-se a deficiência de capacitação, a ausência de uma plataforma de geração e compartilhamento de conhecimentos e dificuldades de cadastramento das atividades de extensão. O estudo resultou na elaboração de dez estratégias para o gerenciamento das etapas do processo de curricularização de maneira institucionalizada.
extract of Schinus terebinthifolius Raddi intensifies morphological alterations in the colon of diabetic rats
Authors: Silva Camiliany Pereira da , Araújo Marcelo Wecsley Ferreira , Sehaber-Sierakowski Camila Cavicchioli , Frez Flávia Cristina Vieira , Iwanaga Camila Cristina , Gois Marcelo Biondaro , Zanoni Jacqueline Nelisis , Moreira Neide Martins , Hermes-Uliana Catchia
Published: April 2024

There are several challenges in the treatment of diabetes mellitus. Some of these challenges include the discovery of bioactive compounds with the potential to be adjuncts in the treatment of diabetes mellitus. In this study, the effects of hydroethanolic extract of Schinus terebinthifolius Raddi on physiological, morphological, and quantitative parameters of the colon of diabetic rats were investigated. For this purpose, 16 90-day-old rats were randomly divided into four groups: Normoglycemics (N); normoglycemics treated with (50 mg/kg) the hydroethanolic extract of S. terebinthifolius Raddi (NA); streptozotocin-induced diabetics (D); and streptozotocin-induced diabetics treated with the hydroethanolic extract of S. terebinthifolius Raddi (DA). The diabetic rats had diarrhea, weight loss, increased water and food intake, and high blood glucose levels. In addition, atrophy of the entire intestinal wall and submucosa, hypertrophy of the muscularis mucosae, and changes in the histoarchitecture of the intestinal crypts and enterocytes were observed in groups NA, D, and DA. In addition, changes in collagen remodeling and the ganglia of the enteric nervous system, as well as changes in goblet cells and intraepithelial lymphocytes, were observed only in groups D and DA. Our results show that treatment with S. terebinthifolius Raddi extract does not protect the colon from the damage caused by diabetes, nor does it reverse physiological parameters. Moreover, the treatment caused morphological and quantitative changes in the colon of normoglycemic rats and intensified the damage caused by diabetes.
THE POSSIBILITY OF USING STRUCTURAL DAMPING IN THE DESIGN OF A PREFABRICATED TURNING CUTTER TO REDUCE THE AMPLITUDE OF SELF-OSCILLATIONS IN THE PROCESS OF METAL CUTTING
Authors:   Department of Mechanics and Automation Engineering, Lviv Polytechnic National University, Novitskyi Maksym , Novitskyi Yurii ,   Department of Mechanics and Automation Engineering, Lviv Polytechnic National University, Slipchuk Andrii ,   Department of Mechanics and Automation Engineering, Lviv Polytechnic National University
Published: April 2024

A mathematical model of four mass oscillating circuit cutting machine was developed and studied in this paper. The influence of the internal friction in the joints of structural elements on the machine tool vibration amplitude and details. Effective self-oscillation amplitude blanking tool is possible by choosing the optimal parameters of the tool body frictional connection with tool holders
Effect of Strategic Planning on Service Quality in the Higher Education Sector
Authors: Taroum Alauldin Salih Ammar , Masaud Khairi Ahmed R.
Published: April 2024

Universities, in general, and in developing countries in particular, have faced significant challenges in recent years due to rapid global changes and developments in the business environment. High-efficiency and high-quality universities are now the ones capable of facing these challenges, competing, and staying in the market. To confront these challenges, strategic planning is essential for universities to continue providing high-quality educational services. Therefore, this study aimed to test the impact of strategic planning on service quality in the higher education context in Libya. Data was obtained through a survey of 360 employees at Sabratha University in Libya. The results showed a positive impact of strategic planning on quality service in higher education. The study included some limitations and directions for future research.
Refining energy efficiency and flexibility strategies using the smart readiness indicator. A comparative case study in Slovenia and Croatia
Authors:   Jožef Stefan Institute - Energy Efficiency Centre, Ljubljana, Slovenia, Sučić Boris , Jurjević Ružica ,   Energy Institute Hrvoje Požar, Zagreb, Croatia, Bišćan Marko ,   Energy Institute Hrvoje Požar, Zagreb, Croatia, Stegnar Gašper ,   Jožef Stefan Institute - Energy Efficiency Centre, Ljubljana, Slovenia
Published: April 2024

Energy and resource efficiency in combination with renewable energy sources constitute the backbone of fu-ture sustainable development in any sector. In this context, the reduction of energy consumption in buildings com-bined with the wide integration of renewable energy sources (RES) in urban areas are vital elements for the long-term transition towards a carbon-neutral society. The EU has identified buildings as the most promising target for improv-ing energy efficiency and has quantified a significant energy-saving potential associated with infrastructure and equipment investments. The calculation of the Smart Readiness Indicator (SRI) involves data collection from various aspects of a building's design, operation, and usage. During the data collection process, the SRI auditor had to ex-tract useful data from drawings, daily log sheets, predefined readings from various Supervisory Control and Data Acquisition systems (SCADA), and from the interview with the energy and/or facility managers, building occupants, and owners. Proper interpretation of SRI scores is crucial for the identification of the energy efficiency and flexibility potentials. This paper presents a comparative case study on the application of SRI in Slovenia and Croatia, focusing on the extraction of energy efficiency and flexibility measures. Additionally, this paper provides general elements of the code of conduct for the smart readiness rating. These elements of the code of conduct for smart readiness rating should be considered as a quality indicator for clients (building owners, facility managers, building users, etc.) on what they should expect and require from SRI auditors in order to achieve expected benefits. Additionally, the strengths and weaknesses of SRI auditing and its role in the decision-making process, specifically in the selection of the optimal energy-renovation scenario, were critically reviewed.
Simulation of the energy performance of potential HVAC systems and implementation of renewable energy sources to achieve nZEB on the example of an office building in Nis
Authors:   Academy of Applied Technical and Preschool Studies Vranje Department, Vranje, Serbia, Jovanović Vladan , Ignjatović Marko ,   Faculty of Mechanical Engineering, University of Niš, Niš, Serbia
Published: April 2024

One of the key approaches to achieving an optimal balance between energy consumption and overall comfort in existing buildings lies in the use of sophisticated simulations for efficient management of HVAC systems. Modeling and simulating the energy performance of buildings represent a highly advanced technique that enables the predic-tion of complex system behaviors based on physical laws and principles. These simulations allow for precise solving of thermal equilibrium equations, taking into account all essential physical characteristics of the building, the com-plexity of the mechanical systems serving it, as well as a wide range of dynamic input variables throughout the entire calendar cycle. Critical factors significantly influencing energy consumption in buildings are region-specific climatic condi-tions, as well as individual user expectations regarding indoor temperature, humidity, and air quality. The methodology of this advanced research is based on the use of the state-of-the-art simulation tool Ener-gyPlus, which enables a detailed analysis of the building's energy performance. This holistic approach enables the enhancement of energy efficiency in existing buildings and optimization of HVAC system operation, resulting in significant energy savings and improved overall user comfort. Furthermore, this study aims to demonstrate the improvement of building systems themselves to achieve nZEB buildings and the utiliza-tion of renewable energy sources. The work is expected to use simulations of the model, along with additional systems, to minimize the net site en-ergy through PV panel-integrated systems compared to the model without such systems. The results obtained from the baseline model already demonstrate low energy requirements, while the use of PV panels is expected to result in even lower consumption. The total energy required to meet the building's energy needs is 41,109.67 kWh, which translates to 36.41 kWh/m² of the total building area. The paper will also demonstrate a reduction in CO2 emissions compared to the model without PV panel-integrated systems.
Analysis of the heat pumps applicability in the district heating system
Authors:   Univerzitet u Novom Sadu, Fakultet tehničkih nauka, Novi Sad, Srbija, Kljajić Miroslav
Published: April 2024

The main intention of the work is to check and analyze the applicability of heat pumps in the district heating system, in accordance with the criteria defined by the Integrated national energy and climate plan. It is basically an integrated solution that has various implications for the energy system, which are of a technical, economic and envi-ronmental nature. Modern district heating system can integrate low-emission or climate neutral energy sources and technologies, especially in urban settings where neighborhood solutions can work well. The advantages and disad-vantages of investing in such systems need to be carefully assessed in each case and in relation with other, potentially more cost-effective and sustainable local solutions. Presented strategy highlights the twin benefits, environmental risks mitigation and security of supply improvement, combining energy efficient technology and conservation measures with switching to waste energy use in district heating system. The proposed development strategy of the utility company includes the development of new heat sources, the revitalization of existing systems, and consume expansion. Development of new heat sources involves building of a new heat pump capacity in parallel with the introduction of locally available heat sources and increase the availabil-ity of the heat supply service to a larger number of consumers. Existing district heating system lacks capacity (in near future), and instead of building new boilers, a heat pump can be a suitable alternative. Heat production by the heat pumps can sustainably utilize the heat energy of purified water from the Waste water treatment plant, and thus substi-tutes the combustion of natural gas in the heating plants’ boilers. Aim of proposal idea is utilization of waste low-temperature heat out of wastewater by a heat pump and feed in the district heating network. Wastewater from the city is collected in a sewer system and treated in a wastewater treatment plant in the northern part of the city. An integral part of the concept is the construction of the missing hot water routes and interconnections (4 km of district heating pipeline is required), as well as the modernization of the heating substations. To utilization of waste heat out of wastewater by a heat pump, the 3 separated networks could be connected to gain a continuous and integrated operation. This is necessary to fully utilize the potential of the heat pumps’ production. This paper was prepared in the framework of „The Renewable District Energy in the Western Balkans Pro-gramme (the ReDEWeB Programme)” as support to integrated urban and sustainable energy systems, which is fi-nanced by the Austrian government and supported by the European Bank for Reconstruction and Development (EBRD). The concept is the result of good cooperation between programme participants and the Public utility compa-ny “Drugi oktobar”, Vršac.
Arte desplegable
Authors: Bidart Max
Published: April 2024

Mathilde Arnaud, diseñadora francesa y experta en libros pop-up, comparte en esta entrevista su fascinante viaje desde el descubrimiento autodidacta de la técnica de libros desplegables hasta consolidarse como artista internacional del papel. Su historia es una odisea de creatividad y perseverancia. Aunque vivir de la ingeniería del papel puede ser desafiante por la variabilidad de ingresos, Mathilde equilibra encargos, talleres y proyectos personales para mantener su carrera. Ofrece valiosos consejos para aquellos que deseen adentrarse en el mundo del pop-up, destacando la importancia de la práctica y la experimentación.
Outcome in dogs with invasive adrenal gland tumors that did not pursue adrenalectomy
Authors: Fontes Gabrielle S. , Piegols Hunter J. , Lapsley Janis M. , Bracha Shay , Selmic Laura E.
Published: April 2024

OBJECTIVE

To report the survival times in dogs diagnosed with adrenal tumors with vascular or soft tissue invasion that did not undergo adrenalectomy.

ANIMALS

Retrospective case series of 32 client-owned dogs.

METHODS

The medical records of a referral veterinary hospital were reviewed to identify dogs that were diagnosed with an invasive adrenal mass and did not undergo adrenalectomy between January 2013 and December 2022. Data collected included signalment, examination findings, and diagnostic results from the initial presentation. Descriptive statistics were calculated to summarize dog signalment information, and Kaplan-Meier survival analysis was performed for calculation of median survival time.

RESULTS

Most dogs (n = 28) had vascular invasion, primarily into the caudal vena cava. Surgery was offered but not pursued due to perceived risk of sudden death (n = 5), risk of hemorrhage (4), or concurrent diagnosis of disseminated intravascular coagulation (1). Only 1 dog pursued stereotactic body radiation therapy, and 1 was prescribed toceranib phosphate (Palladia). Of these 32 dogs, 30 (93.8%) died or were euthanized and 2 (6.2%) dogs survived. The median follow-up time was 49 days (range, 0 to 1,910 days). The median survival time was 50 days (95% CI, 4 to 194 days). The most common cause of death or euthanasia was hemoabdomen (n = 8).

CLINICAL RELEVANCE

Nonsurgical management of invasive adrenal tumors was associated with short survival times in this case series.
High-pathogenicity avian influenza in wildlife: a changing disease dynamic that is expanding in wild birds and having an increasing impact on a growing number of mammals
Authors: Puryear Wendy B. , Runstadler Jonathan A.
Published: April 2024

While diverse strains of low-pathogenicity avian influenza have circulated in wild birds for a long period of time, there has previously been little pathology in wild birds, ducks have been the primary and largely asymptomatic wild reservoir, and spillover into mammals has been limited and rare. In recent years, a high-pathogenicity avian influenza (HPAI) virus has emerged on the global scene and shifted the previously established dogmas for influenza infection. High-pathogenicity avian influenza has expanded into wildlife in unprecedented numbers and species diversity, with unmatched disease severity for influenza in wildlife. As the disease ecology of influenza has shifted with this new variant, significant efforts are underway to understand disease course, pathology, and species susceptibility. Here we focus primarily on the impact that HPAI has had in wild mammals while framing these novel spillovers within the context of significantly expanding disease in avian species and geography. The clinical and pathology presentations of HPAI in these atypical hosts are discussed, as well as prognosis and risk for continued spillover. The companion Currents in One Health by Runstadler and Puryear, AJVR, May 2024, provides further context on viral reservoirs and possible routes of direct or environmental transmission and risk assessment of viral variants that are emerging within wildlife.
Anthocyanins - dietary natural products with a variety of bioactivities for the promotion of human and animal health
Authors: Yeung Andy Wai Kan , Solka Magdalena , Jóźwik Artur , Ksepka Natalia , Matin Maima , Wang Dongdong , Zielińska Aleksandra , MohanaSundaram ArunSundar , Vejux Anne , Zarrouk Amira , Tewari Devesh , Horbańczuk Jarosław Olav , Lucarini Massimo , Durazzo Alessandra , Ghzaiel Imen , Michalczuk Monika , Rezig Leila , Tzvetkov Nikolay T. , Matin Farhan Bin , Lizard Gérard , Bishayee Anupam , Devkota Hari Prasad , El-Demerdash Amr , Brnčić Mladen , Santini Antonello , Mickael Michel-Edwar , Horbańczuk Olaf , Charuta Anna , Szafrańska Karina , Małachowska Ewa , Wieczorek Marek , Siddiquea Bodrun Naher , Hrg Dalibor , Frazzini Sara , Rossi Luciana , Singla Rajeev K. , Wieczorek Anna , Łysek-Gładysinska Małgorzata , Chandragiri Siva Sai , Adamska Olga , Stolarczyk Artur , Klusek Justyna , Szymańska-Czerwińska Monika , Niemczuk Krzysztof , Hejna Monika , Sztandarski Patryk , Jaszczyk Aneta , Michnowska Hanna , Tomasik Cyprian , Zima-Kulisiewicz Bogumila , Marchewka Joanna , Ławiński Michał , Atanasov Atanas G.
Published: April 2024

Anthocyanins are water-soluble pigments contained in numerous food plants. This study provides an overall quantitative literature analysis on anthocyanins. Bibliometric data were collected through the search string TOPIC = anthocyan*, which yielded 44,121 publications indexed within the Web of Science Core Collection. Term maps were generated using VOSviewer software to visualize frequently mentioned terms alongside their citation data. The literature has been growing fast since the 2000s and predominantly consists of original articles, with a ratio of 13.8:1 compared to reviews. The most productive author was Professor Victor de Freitas from the University of Porto, whereas the most productive countries were China and the United States. Many publications were published in food science & technology and plant sciences journals. Frequently mentioned chemicals/chemical classes included anthocyanin, flavonoid, cyanidin, phenolic compound, and polyphenol. Recurring food items of the anthocyanin papers were grapes, many berries, and specific varieties of rice, maize, potato, and tomato.
Calcareous seaweed in the diet of growing Japanese quail
Authors: Rezende Ester Bertoldo , Valentim Jean Kaique , Garcia Rodrigo Garófallo , de Castro Burbarelli Maria Fernanda , Komiyama Cláudia Marie , Serpa Felipe Cardoso , Caldara Fabiana Ribeiro , Zanella Joyce , Braz Paulo Henrique , de Almeida Alexander Alexandre , Felix Gisele Aparecida
Published: April 2024

In this way, the present study assessed the replacement of inorganic calcium sources by organic sources in the diet of growing Japanese quails. The study analyzed 300 Japanese quails distributed in a completely randomized design with 3 treatments (control, 0% inclusion; 0.50% inclusion of calcareous seaweed 1; 0.50% inclusion of calcareous seaweed 2, with both inclusions concerning the replacement of calcitic limestone in the diet). Calcium sources did not differ in terms of either the production performance of birds in the growth phase or at the beginning of laying or in terms of yield, weight, organ size or bone quality. The biochemical blood profile did not change, except for the AST index. The replacement treatment affected egg quality, colorimetric fan color, albumen and yolk height, Haugh unit, and the yolk index. Including 0.50% calcareous seaweed as a replacement for calcitic limestone in the diet of quail does not harm production performance, animal health, organ yield, or bone quality in the growth phase. This diet guarantees satisfactory performance and high-quality eggs in the early laying phase.
The Mutual Influence of Labour Market Polarisation, Wage Polarisation and Political Polarisation in the European Union
Authors: Rolník Ondřej , Adamková Katarína
Published: April 2024

The aim of the paper is to prove a hypothesis concerning the dependence of the political polarisation of the European Union on recent developments in labour market structure. The labour market is undergoing changes that stem from technological progress as well as outsourcing of low-skill activities, which are causing an increase in labour market and wage polarisation. The premise is that the depopulation of the middle class is increasing political polarisation. The hypothesis is tested on a sample of 27 European Union countries from 1990 to the present using OLS with fixed effects regression analysis. Political polarization is represented by an own constructed political polarization index based on the ideological division of political parties’ data of the ParlGov project (2022). The index is constructed by combining the election results and four ideological spectrums. In conclusion, the dependence of political polarisation on labour market polarisation and wage polarisation is rejected.
Microstructural Characterisation of Adsorbent Ash with Potentially Toxic Elements in a Mortar
Authors: Naser Heba , Al-Labadi Ibrahim G. , Dorkota Andrea , Czinkota Imre , Horváth Márk
Published: April 2024

Potentially toxic elements (PTEs) in ecosystems and construction materials pose a significant environmental concern. Various qualitative and quantitative techniques are employed to analyse PTEs in a sample. This study explores an innovative approach that incorporates PTE (Cd, Zn, Cu, Pb) adsorbent ash, specifically adsorbed paper ash (APA) and adsorbed mulch ash (AMA), into mortar composites. This approach offers several advantages, including reduced reliance on waste landfills, energy recovery during the ashing process, and immobilisation of PTEs within a cement matrix. This study evaluated the elemental and microstructural characteristics of mortar composites incorporated with adsorbed ash by using a scanning electron microscope (SEM) equipped with energy-dispersive X-ray spectroscopy (EDS), followed by analysing the elemental maps with ImageJ software version 1.8.0. Parallel experiments were conducted to measure the leaching of mortar composites. The total elemental content of PTEs in the leachate solutions was quantified using an inductively coupled plasma-optical emission spectrometer (ICP-OES). The differences in adsorption capacity and leaching of PTEs observed between paper and mulch can be ascribed to their distinct affinities, which are influenced by the recorded pH levels. The examined elemental mapping revealed a consistent distribution across the APA and AMA mortar matrix structures, with greater intensity than the blank mortar sample. Furthermore, there is a reverse correlation between the order of percentage area coverage of the immobilised elements and the order of leaching, indicating that the PTEs were successfully immobilised. The percentage of PTE area coverage within AMA mortar composites followed the subsequent order: Pb > Cd > Zn > Cu, constituting 32.1 %, 28.6 %, 13.8 %, and 12.4 %, respectively. This order was also observed in the blank mortar composite, with percentages of 12.5 %, 8.6 %, 4.5 %, and 4.2 %, respectively. In the case of the APA mortar composite, the percentage of area coverage followed a different sequence: Cd > Pb > Zn > Cu, representing 27.7 %, 26.6 %, 14.5 %, and 14.1 %, respectively. The results also demonstrated notable improvements in the microstructure of the mortar when AMA and APA are incorporated, which is attributed to the ash additives’ micro-filling capacity. The findings contribute to advancing environmentally sound construction practices, with implications for sustainable waste management and pollution mitigation.
Systemic immune-inflammation index as a potential biomarker for predicting acute pulmonary embolism: A systematic review
Authors: Suwadi Andrew , Tandarto Kevin , Laksono Sidhi
Published: April 2024

Background

Acute pulmonary embolism (APE) is a life-threatening condition with a high mortality rate. The pathophysiology involves various complex processes. The systemic immune-inflammatory index (SII) is a well-known biomarker that reflects the intricate balance between pro-inflammatory and anti-inflammatory immune components. In this systematic review, we aim to determine the significance of SII as a potential biomarker for APE.

Method

We utilized PubMed, ProQuest, EBSCOHost, and Google Scholar to search for articles. We assessed bias risk using the Newcastle Ottawa Scale (NOS). The outcomes we examined included in-hospital and long-term mortality, the severity of APE, and the sensitivity and specificity of the SII in predicting APE.

Results:

Four studies, involving 2,038 patients, were included for analysis. These studies discuss the use of SII in predicting APE severity, APE mortality, high-risk APE, and the occurrence of APE. SII demonstrates significant results in predicting each of these variables. Furthermore, each study establishes different SII cut-off values. Specifically, a cut-off of 1161 predicts massive APE events with a sensitivity of 91% and a specificity of 90%. A cut-off of >1235.35 differentiates high-risk APE with a sensitivity of 87.32% and a specificity of 68.85%. A cut-off of >1111x109 predicts overall mortality with a sensitivity of 72% and a specificity of 51%. Finally, a cut-off at 1839.91 predicts APE events with a sensitivity of 75.8% and a specificity of 61.9%.

Conclusion

The SII can be employed as a potential new biomarker to predict outcomes in APE patients, particularly the occurrence, severity, and mortality of APE.
The Perceived Nighttime Economy Impacts: Its Binary and Multidimensional Natures
Authors: Nghiêm-Phú Bình , Hoàng Trang Thị-Thu , Phạm Hồng Long
Published: April 2024

Purpose: This study examines the perceived impacts of the nighttime economy in an emerging country: Vietnam.
 
Theoretical framework: The literature about the nighttime economy in developed contexts was reviewed to guide this study.
 
Method/design/approach: Two exploratory studies were implemented. The first one involved the qualitative analysis of user-generated content. The second one was related to an analysis of data gathered via a structured survey.
 
Results and conclusion: The qualitative analysis of public opinions (n = 538) revealed the positive and negative aspects of the perceived impacts. The quantitative survey (n = 352) exposed the hidden elements of the perceived impacts, including the economic, sociocultural, environmental, and health impacts.
 
Research implications: The differences in findings between this study and the prior research were highlighted to expand the literature on the nighttime economy. Implications for local administrators when projecting and managing this new economic activity were also discussed.
 
Originality/value: The binary and multidimensional natures of nighttime economy impacts are simultaneously taken into account to enrich the literature on these particular issues.
A case of successful treatment of arterial and biliary complications in a patient after liver transplantation
Authors: Ishchenko I. O. , Tileubergenov I. I. , Zhuikov V. N. , Sheraliev A. R. , Polikarpov A. A. , Moiseenko A. V. , Granov D. A.
Published: April 2024

In April, 2018, a 57-year old patient with cirrhosis of the liver (Child-Turcotte-Pugh B class) during the outcome of viral hepatitis B and C was performed Transjugular Intrahepatic Portosystemic Shunt (TIPS); and in June, 2018 – liver transplantation (LТ) from a deceased donor by Piggyback technique. In the postoperative period, abscesses in the left and right lobes of the liver and thrombosis of the hepatic artery thrombosis (HAT) were noticed. Balloon dilatations of biliary stricture with changes of biliary drainage were made during the period of 2 years. In May, 2022, according to the results of angiography, hepatic artery and its branches were seen up to segmental level that meant natural revascularization. Considering the low efficiency of the balloon plastic procedures carried out, there was formed trihepaticojejunostomy on the loop of the small intestine disconnected according to Roux-en-Y. The follow-up period is one and a half years; there are no signs of cholangitis and biliary hypertension.

There is no unified scheme of treatment for vascular and biliary complications in the clinics engaged in LТ, because every technique has both advantages and disadvantages. The idea of choice between intervention revascularization, transplantation and surgical reconstruction in the treatment of arterial thrombosis still remains incompletely understood.
Diagnóstico de manejo de residuos y síntomas en salud en plaza de mercado en zona urbana del suroccidente Colombiano
Authors: Agredo-Hernández Erika J , Lara-Chicangana Yauri A , Montenegro-Valdes Derikson , Muñoz-Solarte Diana M
Published: April 2024

La plaza de mercado La esmeralda se ubica en Popayán (Cauca), un municipio del Suroccidente Colombiano, es un lugar de suministro de productos agrícolas, considerada como un punto crítico por el manejo de residuos y el deterioro de su entorno, que afecta principalmente a comerciantes de la zona. El objetivo fue evaluar el manejo de residuos e identificar los síntomas en salud más comunes en los comerciantes del sector. Se llevó a cabo una inves-tigación descriptiva empleando lista de verificación, encuestas, entrevistas y narrativas con los comerciantes de la plaza. La información recopilada se sistematizó utilizando Microsoft Excel y se importó al programa BioEstat 5.0 para analizar las variables socio-demográficas, ocupacionales y realizar pruebas Chi2 para comparar la relación entre condiciones de sociodemográficas, estilo de vida, manejo de residuos y síntomas presentados. Se establece un incumplimiento del 67% para planes y programas y un 90% para los aspectos ambientales, reflejando de mane-ra significativa el problema organizacional frente a programas ambientales en la plaza de mercado. En el aspecto salud, el 75% de los comerciantes presentan síntomas gastrointestinales, 65.6% diarrea y 53.12% náuseas o vómi-tos. Se identificó la inadecuada disposición de residuos como un factor que podría agravar los problemas ambien-tales y de salud en el sector. Adicional, se evidenció que el 65.6% de los comerciantes no recibieron capacitación para el manejo de residuos, destacando la necesidad de estrategias de educación ambiental acerca de manejo y disposición adecuada de residuos, se recomienda implementarlas de manera continua dirigidas a los comerciantes y a la población en general, con el objetivo de mejorar las condiciones de salud, fomentar el autocuidado y reducir la vulnerabilidad a enfermedades.
Efecto de enmiendas orgánicas sobre las características agronómicas y producción de pepino (Cucumis Sativus L.)
Authors: López-Bósquez Jonathan , Salazar-Saltos Alex , Durán-Mera Christian , Pincay-Ronquillo Wellington , Solano-Apuntes Alex , Zambrano-García Gloria , Chusin-Gray Luis
Published: April 2024

La producción alimentaria preocupa por el aumento poblacional y la degradación de los suelos debido a su manejo insostenible. Mejorar el rendimiento sostenible del pepino es crucial dada su alta demanda mundial. Se evaluó el impacto de enmiendas orgánicas en la producción de pepino en El Moral, La Maná, Cotopaxi, Ecuador, durante mayo-agosto de 2022. Se emplearon siete tratamientos que abarcaron tres enmiendas orgánicas, tres fuentes minerales y un control sin enmiendas. El diseño experimental fue de bloques completos al azar con cuatro repeticiones y treinta plantas por unidad experimental. Se evaluó la altura de planta, diámetro del tallo, número de hojas a los cuarenta y cinco días después de la siembra, a la cosecha se evaluó la longitud, diámetro, peso del fruto y finalmente el rendimiento por hectárea. Las variables en su mayoría fueron significativas (P>0,05). El humus de lombriz y compost tuvo influencia directa en la altura de planta y número de hojas superando a las fuentes minerales, lo que demuestra los beneficios sobre este tipo de especies vegetales. El rendimiento de pepino superior con las enmiendas orgánicas, destacando el humus de lombriz con el mayor rendimiento 16.775 kg·ha-1.
حزب الشعب الجزائري وموقفه من الاحتلال الفرنسي (1937-1945م )
Authors: ابراهيم ياس خضير
Published: April 2024

ان الفترة التاريخية الواقعة بين 1937-1945م تعتبر من الفترات والمراحل التاريخية المهمة في تاريخ الجزائر الحديث والمعاصر ، اذ شهدت هذه الفترة التاريخية وكذلك الفترة التي سبقتها تحركا كبيرا للقوى الوطنية على المستوى السياسي والتنظيمي من اجل مواجهة الاستعمار الفرنسي والضغط عليه واجباره على الانصياع لمطالب الشعب الجزائري ، فشهدت هذه الفترة ظهور احزاب سياسية فعالة على الساحة الجزائرية ،اخذت تلك الاحزاب تعمل على المطالبة بالحقوق الوطنية للشعب الجزائري والمتمثلة بتحقيق الحرية والاستقلال والتخلص من الهيمنة الفرنسية على مقدرات الشعب الجزائري .
  ومن بين هذه الاحزاب حزب الشعب الجزائري الذي تأسس في 11|آذار|1937م ، وبدأ نشاطه السياسي الى جانب القوى الوطنية في الجزائر في مقارعة الاستعمار الفرنسي من خلال تنظيمه للاحتجاجات الشعبية او من خلال الصحف الذي كان يصدرها ، اذ كان يمثل واحدة من النماذج الوطنية التي مارست دورها الوطني في مواجهة الاستعمار الفرنسي ، مما دفع الحكومة الفرنسية الى حل الحزب في عام 1939م ،لكن على الرغم من قرار الحكومة الفرنسية بحل الحزب الا ان الحزب بقي يعمل في مواجهة الاستعمار الفرنسي ولكن بصورة سرية .
Conservative treatment in hemifacial spasm due to vertebrobasilar dolichoectasia
Authors: Supit Vincentius Diamantino , Adrianto Yudhi , Setyowatie Sita
Published: April 2024

Primary or secondary hemifacial spasm (HFS) can be caused by a variety of conditions, one of which is caused by neurovascular contact with a vertebrobasilar dolichoectasia (VBD). Microvascular decompression (MVD) had been known for the treatment of neurovascular contact that gives best outcome, however there were still limitations which surgery cannot be performed. In that case, conservative treatment plays essential role. Our case reported A 69-year-old man with chief complaint right HFS for four years that getting better with conservative treatment (blood pressure management and clonazepam oral).
Performance analysis methodology of deep neural networks inference on the example of an image classification problem
Authors: Алибеков М.Р. , Березина Н.Е. , Васильев Е.П. , Вихрев И.Б. , Камелина Ю.Д. , Кустикова В.Д. , Маслова З.А. , Мухин И.С. , Сидорова А.К. , Сучков В.Н.
Published: April 2024

Внедрение глубоких нейронных сетей требует анализа производительности этапа вывода на целевом аппаратном обеспечении. Результаты производительности позволяют принимать решение о возможности внедрения построенных моделей и/или необходимости их предварительной оптимизации. В работе описана методика анализа и сравнения производительности вывода на примере решения задачи классификации изображений: конвертация обученной модели под разные фреймворки, анализ качества, определение оптимальных параметров запуска вывода, оптимизация модели и повторный анализ качества, анализ и сравнение производительности. Разработана система Deep Learning Inference Benchmark для поддержки цикла анализа производительности. Методика продемонстрирована на примере открытой модели MobileNetV2.

Deploying of deep neural networks requires inference performance analysis on the target hardware. Performance results are aimed to be used as motivation to evaluate a decision for deployment, find the best performing hardware and software configurations, decide is there’s a need for optimization of DL model and DL inference software. The paper describes a technique for analyzing and comparing inference performance using an example of image classification problem: converting a trained model to the formats of different frameworks, quality analysis, determining optimal inference execution parameters, model optimization and quality reanalysis, analyzing and comparing inference performance for the considered frameworks. Deep Learning Inference Benchmark Tool is aimed to support the performance analysis cycle. The technique is implemented on the example of the MobileNetV2 model.
Planar Patch Clamp and Techniques of Patch-Clamp Spectroscopy in Antimicrobial Therapy
Authors:   Federal Research Center of Chemical Physics RAS, Department of Dynamics of Chemical and Biological Processes, Russia, F Orehow , E Adamovic ,   Federal Research Center of Chemical Physics RAS, Department of Dynamics of Chemical and Biological Processes, Russia, O Gradow ,   Federal Research Center of Chemical Physics RAS, Department of Dynamics of Chemical and Biological Processes, Russia
Published: April 2024

Planar patch-clamp is an effective screening tool in pharmacology, institutionalized in molecular microbiology over 15 years ago [1]. The creation of planar polymer patch-clamp electrodes and silicon substrates in the 2000s [2,3] and the creation of microfluidic chips and perfusable chambers corresponding to this pharmacological screening technology, although works on the development of microfluidic chips for planar patch-clamp were already being published in the early to mid-2000s, and the first "benchmark study" of a chip for planar patch-clamp dates back to 2003 [4,5]. At the moment, there are automated and robotic schemes for planar patch-clamp, including those available for sale and maintenance [6-8]. In the CIS, this method is not widespread, however, devices such as the "Patchliner" with planar patch-clamp, capable of recording up to 8 cells synchronously, are available [9-11]. Patch-clamp tools can be used in the development of drugs and antimicrobial agents, screening of which can be performed on E. coli, etc. [12-14]. The response of the organism mediated by lysosomes can also be the subject of using this method, as lysosomal ion currents can also be measured in planar patch-clamp systems [PMID: 21139138].
In Rats, the Chemotherapeutic Drug Vincristine-Induced Neuropathic Nociception is Suppressed When Cannabinoid CB1 and CB2 Receptors are Activated
Authors:   Apollo College of Pharmacy, Anjora, Durg CG, India, Sonwani Hari Prasad
Published: April 2024

Rats were used to test the potential of cannabis to reduce mechanical hypersensitivity, or mechanical allodynia, which was brought on by vincristine chemotherapy. After that, action sites were located. Method of experimentation: After ten daily injections of vincristine, mechanical hypersensitivity developed in comparison to those that received saline at the same periods. The effects on chemotherapy-induced neuropathy were assessed for the CB1/CB2 receptor agonist WIN55, 212-2, the receptor-inactive enantiomer WIN55, 212-3, the CB2-selective agonist (R,S)-AM1241, the opiate agonist morphine, and vehicle. To determine the locations of action, WIN55, 212-2 was injected either locally in the hind paw or intrathecally (i.t.). By employing competitive antagonists for either CB1 (SR141716) or CB2 receptors (SR144528), pharmacological selectivity was demonstrated. Vincristine-evoked mechanical allodynia was decreased when WIN55, 212-2, but not WIN55, 212-3, were administered systemically. A change in the dose-response curve to the left was noticed after WIN55, 212-2 in comparison to morphine therapy. Antibodies of CB1 (SR141716) and CB2 (SR144528) inhibited WIN55, 212-2’s anti-allodynic actions. Via a CB2 mechanism, (R,S)-AM1241 reduced c-induced mechanical hypersensitivity. Without causing catalepsy, both cannabinoid agonists reduced the mechanical hypersensitivity brought on by vincristine. Cannabis-induced neuropathy may be modulated by cannabinoids at spinal sites of action. When delivered intraperitoneally, WIN55, 212-2 but not WIN55,212-3 inhibited vincristine-evoked mechanical hypersensitivity at dosages that were inert after local hindpaw injection. Spinal co-administration of CB1 and CB2 antagonists inhibited WIN55,212-2’s anti-allodynic effects.By activating CB1 and CB2 receptors, cannabinoids inhibit the maintenance of vincristine-induced mechanical allodynia. The spinal cord is involved in the mediation of these anti-allodynic actions, at least partially.
Medication Regimens against Hypertension Utilized in the Systolic Blood Pressure Intervention Stud
Authors:   B.Pharmacy, Student, Apollo College of Pharmacy, India, Bandey Rashi , Sonwani Hari Prasad ,   Assistant Professor, Apollo College of Pharmacy, India
Published: April 2024

Context: Standard and intensive Systolic Blood Pressure (SBP) interventions would be contextualized by describing the antihypertensive medication regimens used in the SPRINT (Systolic Blood Pressure Intervention Trial). This information may also help future implementation efforts to meet population-wide intensive SBP goals. Methods: At the rerandomization and 12-month visits, we provided SPRINT participants with comprehensive medication data. The class of antihypertensive medications was used to categorize regimens. The analyses were divided into groups based on the kind of treatment (intensive target SBP <120 mm Hg versus standard goal SBP <140 mm Hg) Findings: The median number of classes used at the rerandomization visit was 2.0 for 7860 individuals (83.7% of 9361 randomized), and 2.0 for the standard and intensive groups (P=0.559). After a year, the intensive and conventional groups used a median of 3.0 and 2.0 classes, respectively (P<0.001). In the intensive and standard groups, the most common regimens were rerandomization, Angiotensin-Converting Enzyme inhibitor (ACE), or Angiotensin-II Receptor Blocker (ARB) monotherapy (12.6% versus 12.2%). After a year, 5.3% of participants in the intense group and 14.7% of participants in the normal group still used ACE/ARB monotherapy. The following multidrug regimens were utilized at 12 months by both the intensive and regular participants: a calcium channel blocker and thiazide (12.2% and 7.9%) combined in an ACE/ARB thiazide, and calcium channel blocker (11.4% and 4.3%); an ACE/ARB, thiazide, calcium channel blocker, and beta-blocker (6.5% and 1.2%); and 6.2% and 6.8% of each category. Conclusions: Compared to ACE/ARB monotherapy, SPRINT investigators preferred combining ACEs or ARBs, thiazide diuretics, and calcium channel blockers to aim SBP <120 mm Hg.