bluuebunny/crossref_metadata_2025 huggingface dataset:
SOX17 promoter methylation in plasma circulating tumor DNA of patients with non-small cell lung cancer
Authors: Balgkouranidou Ioanna , Chimonidou Maria , Milaki Georgia , Tsaroucha Emily , Kakolyris Stylianos , Georgoulias Vasilis , Lianidou Evi
Published: January 2016

SOX17 belongs to the high-mobility group-box transcription factor superfamily and down-regulates the Wnt pathway. The aim of our study was to evaluate the prognostic significance of

We examined the methylation status of

In operable NSCLC,

Our results show that
Analytical and clinical evaluation of the new Fujirebio Lumipulse®G non-competitive assay for 25(OH)-vitamin D and three immunoassays for 25(OH)D in healthy subjects, osteoporotic patients, third trimester pregnant women, healthy African subjects, hemodialyzed and intensive care patients
Authors: Cavalier Etienne , Lukas Pierre , Bekaert Anne-Catherine , Peeters Stéphanie , Le Goff Caroline , Yayo Eric , Delanaye Pierre , Souberbielle Jean-Claude
Published: January 2016

In this study, we provide a short analytical evaluation of the new Fujirebio Lumipulse

Lumipulse

The Lumipulse

Fujirebio Lumipulse
Internet Alcohol Marketing and Underage Alcohol Use
Authors: McClure Auden C. , Tanski Susanne E. , Li Zhigang , Jackson Kristina , Morgenstern Matthis , Li Zhongze , Sargent James D.
Published: January 2016

BACKGROUND AND OBJECTIVE:

Internet alcohol marketing is not well studied despite its prevalence and potential accessibility and attractiveness to youth. The objective was to examine longitudinal associations between self-reported engagement with Internet alcohol marketing and alcohol use transitions in youth.

METHODS:

A US sample of 2012 youths aged 15 to 20 was surveyed in 2011. An Internet alcohol marketing receptivity score was developed, based on number of positive responses to seeing alcohol advertising on the Internet, visiting alcohol brand Web sites, being an online alcohol brand fan, and cued recall of alcohol brand home page images. We assessed the association between baseline marketing receptivity and both ever drinking and binge drinking (≥6 drinks per occasion) at 1-year follow-up with multiple logistic regression, controlling for baseline drinking status, Internet use, sociodemographics, personality characteristics, and peer or parent drinking.

RESULTS:

At baseline, ever-drinking and binge-drinking prevalence was 55% and 27%, respectively. Many (59%) reported seeing Internet alcohol advertising, but few reported going to an alcohol Web site (6%) or being an online fan (3%). Higher Internet use, sensation seeking, having family or peers who drank, and past alcohol use were associated with Internet alcohol marketing receptivity, and a score of 1 or 2 was independently associated with greater adjusted odds of initiating binge drinking (odds ratio 1.77; 95% confidence interval, 1.13–2.78 and odds ratio 2.15; 95% confidence interval, 1.06–4.37 respectively) but not with initiation of ever drinking.

CONCLUSIONS:

Although high levels of engagement with Internet alcohol marketing were uncommon, most underage youths reported seeing it, and we found a prospective association between receptivity to this type of alcohol marketing and future problem drinking, making additional research and ongoing surveillance important.
Organizar a Desordem: Raízes do Brasil em 1936
Authors: Feldman Luiz
Published: January 2016

Este artigo procura reconstruir o dilema político enfrentado por Sergio Buarque de Holanda na primeira edição de Raízes do Brasil. Sustenta-se que, na montagem do argumento de seu livro de estreia, o autor entabulou diálogos intelectuais com dois importantes pensadores brasileiros, Oliveira Vianna e Gilberto Freyre. O engajamento com a obra desses autores ajudou Sergio Buarque a enunciar os aspectos negativos e positivos do tipo de sociabilidade legado pela colônia – a “cordialidade” –, a diagnosticar a incompatibilidade entre doutrinas políticas e realidade nacional e a procurar uma forma de superar essa disjunção. A ideia da “organização da desordem” reflete a dificuldade de fundar-se um Estado respeitável em uma sociedade eivada de elementos anárquicos sem reprimir o substrato cultural tradicional de sua população.
Identification of changes in kinematics and electromyographic parameters during dual-task gait: a comparative study between young and elderly female subjects
Authors: Hallal Camilla Zamfolini , Spinoso Deborah Hebling , Morcelli Mary Hellen , Fonseca Ligia Cristiane , Gonçalves Mauro , Marques Nise Ribeiro
Published: January 2016

Abstract Introduction : Falls during gait are one of the leading causes of death and injuries in elderly adults. Objective : This study aimed to compare the performance of young (YG) and elderly (EG) adults during dual-task gait (using a traffic light simulator) according to kinematics and electromyographic parameters. Materials and methods : 17 young and 18 elderly physically fit female subjects participated in this study. The volunteers walked on a treadmill under two different conditions: normal gait (M1) and dual-task gait (M2). We recorded EMG signals from the rectus femoris (RF), vastus medialis (VM), vastus lateralis (VL), biceps femoris (BF), tibialis anterior (TA), gastrocnemius lateralis (GL) and soleus (SO). The following kinematic data were obtained: step length, step time and self-selected velocity. Data analysis was performed using Wilcoxon's, Mann-Whitney, T-student tests and T-student for independent samples. The level of significance was set at p < 0.05. Results : For both groups, there was greater muscle activation of the RF, VM, VL, BF and SO during M2 than during M1. The YG showed lower muscle activation of the RF, VM, BF and SO during M2 when compared to EG. The EG had smaller step length than the YG. The step length values detected during M1 were higher than the ones collected during M2. During M2, the YG showed higher step time compared to the EG. Elderly subjects walked at a lower self-selected velocity than young subjects. Conclusions : Our findings suggest that dual-task gait modify the neuromuscular behavior in elderly subjects, increasing the risk of falls.
Effects of Pilates and Classical Kinesiotherapy on chronic low back pain: a case study
Authors: Ribeiro Ivanna Avila , Oliveira Tiago Damé de , Blois Cleci Redin
Published: January 2016

Abstract Introduction : Chronic low back pain (LBP) is characterized by daily lower back pain lasting more than three consecutive months. It may lead to functional disability and can be treated by several physical therapy techniques, including therapeutic exercise. The aim of this study was to investigate the effects of pilates and classical kinesiotherapy on the treatment of pain and functional disability in patients with chronic low back pain. Materials and methods : The study sample consisted of five patients with a diagnosis of chronic low back pain and a mean age of 32.4 ± 15.6 years. A Visual Analogue Scale (VAS) was used for pain assessment, and the Oswestry Disability Index was used to assess functional disability at the beginning and at the end of the intervention. Patients were divided into two groups and received 20 individual sessions of therapeutic exercise at a frequency of two sessions per week. Group A was treated with classical kinesiotherapy and group B was treated with pilates exercises. Statistical analysis was performed using Wilcoxon's test. The significance level was set at 5%. Results : There was a significant reduction in pain (p = 043) and functional disability (p = 042) in both groups. We found no significant differences between the effects of pilates and classical kinesiotherapy on pain and functional disability. Conclusions : We conclude that, in the population studied here, both pilates and classical kinesiotherapy were effective in treating chronic low back pain symptoms, with no significant difference between them.
Assessment of pain in patients with chronic low back pain before and after application of the isostreching method
Authors: Silva Pedro Henrique Brito da , Inumaru Suely Maria Satoko Moriya
Published: January 2016

Abstract Introduction : Chronic low back pain is defined as a painful disorder located between the first and the fifth lumbar vertebra and it is considered to be an important public health problem. In Brazil, approximately 10 million people are disabled as a result of this condition. Objective : To assess pain intensity and functional disability in patients with chronic low back pain before and after application of the Isostreching method. Case studies and methods : In this randomized, controlled experimental trial, 14 female individuals with chronic low back pain, aged 45-60 years, divided into control group (CG) and experimental group (EG), with 7 individuals each, twelve 45-minute sessions were held, in which 9 postures of Isostreching method were carried out in the experimental group. The control group did not undergo intervention. A sociodemographic questionnaire, the visual analogue pain scale (VAS) and the Oswestry disability questionnaire were used before and after the study period in both groups. Results : The assessment of pain and disability in the pre-evaluation period showed no statistically significant difference, whereas scores of pain and disability in the post-evaluation period between the two groups showed a statistically significant difference. The CG also showed no statistical difference for the VAS and Oswestry scores between the pre- and post-evaluation periods, in which it was observed an increase in the pain and disability mean scores between those periods and the experimental group showed significant difference between the scores obtained in these two different periods, before and after collection. Conclusion : it is suggested that the method was effective for the group studied and proved to be suitable for the treatment of chronic low back pain.
Effect of Chlorhexidine on Dentin Bond Strength of Two Adhesive Systems after Storage in Different Media
Authors: Silva Enio Marcos da , Glir Daniel Hatschbach , Gill Allana Walesca Martins Castanho , Giovanini Allan Fernando , Furuse Adilson Yoshio , Gonzaga Carla Castiglia
Published: January 2016

The aim of this study was to evaluate the effect of 2% chlorhexidine (CHX) application during the bonding protocol on microshear bond strength of two adhesive systems, after storage in different media. Seventy-two human molars had their crowns cut in half and embedded in PVC cylinders with acrylic resin. The specimens were randomly divided into experimental groups (n=12) according to the adhesive system (Ambar and Single Bond 2), use of CHX in the bonding protocol, and time interval (24 h and 15 days) in the storage media (distilled water, mineral oil and 1% sodium hypochlorite - NaOCl). Adhesive systems were applied in accordance to manufacturers' recommendations, with or without the use of CHX, and resin composite (Z350 XT) cylinders were placed on the hybridized dentin. After photoactivation, the specimens were stored in distilled water, mineral oil and 1% NaOCl for 24 h and 15 days. Microshear bond strength was determined at a crosshead speed of 0.5 mm/min until fracture. The bond strength data were analyzed statistically by 4-way ANOVA and Tukey's test (α=5%). Use of CHX in the bonding protocol did not cause loss of bond strength in any of the evaluated situations, irrespective of time and storage medium. The storage medium had no influence on bond strength values after 15 days when the bond protocol without CHX application was used. However, the use of CHX in the protocol influenced negatively the bond strength values for Single Bond 2 after 15 days storage in distilled water and 1% NaOCl.
An Indirect Method to Measure Abutment Screw Preload: A Pilot Study Based on Micro-CT Scanning
Authors: Rezende Carlos Eduardo E. , Griggs Jason Alan , Duan Yuanyuan , Mushashe Amanda M. , Nolasco Gisele Maria Correr , Borges Ana Flávia Sanches , Rubo José Henrique
Published: January 2016

This study aimed to measure the preload in different implant platform geometries based on micro-CT images. External hexagon (EH) implants and Morse Tapered (MT) implants (n=5) were used for the preload measurement. The abutment screws were scanned in micro-CT to obtain their virtual models, which were used to record their initial length. The abutments were screwed on the implant with a 20 Ncm torque and the set composed by implant, abutment screw and abutment were taken to the micro-CT scanner to obtain virtual slices of the specimens. These slices allowed the measurement of screw lengths after torque application and based on the screw elongation. Preload values were calculated using the Hooke's Law. The preloads of both groups were compared by independent t-test. Removal torque of each specimen was recorded. To evaluate the accuracy of the micro-CT technique, three rods with known lengths were scanned and the length of their virtual model was measured and compared with the original length. One rod was scanned four times to evaluate the measuring method variation. There was no difference between groups for preload (EH = 461.6 N and MT = 477.4 N), but the EH group showed higher removal torque values (13.8±4.7 against 8.2±3.6 Ncm for MT group). The micro-CT technique showed a variability of 0.053% and repeatability showed an error of 0.23 to 0.28%. Within the limitations of this study, there was no difference between external hexagon and Morse taper for preload. The method using micro-CT may be considered for preload calculation.
Evaluation of Chair-Side Assays in High Microbiological Caries-Risk Subjects
Authors: Saravia Marta Estela , Silva Lea Assed Bezerra , Silva Raquel Assed Bezerra , Lucisano Marília Pacífico , Echevarría Andrea Uribe , Echevarría Jorge Uribe , Nelson-Filho Paulo
Published: January 2016

The aim of this study was to evaluate the commercial chair-side assays Saliva-Check Mutans and ClinproTM Cario L-PopTM in high microbiological caries-risk dental students compared with conventional semi-quantitative colony counting culture-based technique as the reference method. Saliva samples from 93 subjects of both sexes aged 18-26 years were seeded (Köhler and Bratthall method) on plates containing SB-20M culture medium method and 12 subjects with high caries risk were selected. These 12 individuals were subjected to determination of caries risk using two commercial rapid detection chair-side assays (Saliva-Check Mutans and ClinproTM Cario L-PopTM) according to the manufacturers' instructions. The results were analyzed by the Kappa correlation test using SAS statistical software. There was a perfect agreement (Kappa=1) among the three caries risk evaluation methods - chair-side assays and semi-quantitative CFU count (control) - in all subjects. The results suggest that the commercial chair-side assays evaluated in this study may be practical and useful to identify high microbiological caries-risk subjects.
Entre o especialismo e o apoio: psicólogos no Núcleo de Apoio à Saúde da Família
Authors: Sousa Diogo de , Oliveira Isabel Fernandes de , Costa Ana Ludmila F.
Published: January 2016

Resumo: A inserção do psicólogo em equipes multiprofissionais e interdisciplinares para suporte às equipes de saúde da família, a partir da criação dos Núcleos de Apoio à Saúde da Família em 2008, foi priorizada, ainda que sem um claro perfil para sua atuação. Isso levou ao questionamento das implicações de um trabalho voltado à atenção e gestão para a Psicologia. Objetivou-se analisar o processo de implantação do NASF e a prática dos psicólogos em dois municípios do estado do Rio Grande do Norte. Utilizou-se análise de documentos oficiais e roteiros de entrevistas semiestruturadas distintos, para psicólogos (um do município A e dois do município B) e coordenadores (dois, um de cada município). Pôde-se inferir que a atuação psicológica revela enfoques tradicionais e uma reprodução de atividades de outras instituições. Conclui-se que as diferenças nos processos de implantação dos serviços criam os próprios instrumentos para reversão dessa lógica.
Resistência de genótipos de araçazeiros a Meloidogyne enterolobii
Authors: Biazatti Marlon Altoé , Souza Ricardo Moreira de , Marinho Cláudia Sales , Guilherme Denilson de Oliveira , Campos Graziella Siqueira , Gomes Vicente Martins , Bremenkamp Cíntia Aparecida
Published: January 2016

RESUMO: Este trabalho teve por objetivo avaliar a resistência de genótipos de P. cattleyanum a M. enterolobii. O experimento foi conduzido em DIC, com seis tratamentos, constituídospor cinco genótipos de P. cattleyanum, pela goiabeira 'Paluma' (testemunha) e oito repetições constituídas por clones desses genótipos. A classificação quanto à resistência foi determinada de acordo com o fator de reprodução (FR), avaliado aos 135 dias após inoculação com o nematoide. Os genótipos de P. cattleyanum avaliados foram resistentes a M. enterolobii com FR iguais ou inferiores a 0,2.
Pythium insidiosum colitis in a dog: treatment and clinical outcome
Authors: Fujimori Mahyumi , Lopes Erika Rondon , Lima Samara Rosolem , Paula Daphine Ariadne Jesus de , Almeida Arleana do Bom Parto Ferreira de , Colodel Edson Moleta , Pescador Caroline Argenta , Néspoli Pedro Eduardo Brandini , Nakazato Luciano , Dutra Valéria , Souza Roberto Lopes de , Sousa Valéria Régia Franco
Published: January 2016

ABSTRACT: The aim of this report is to describe the clinical, pathological and imaging findings and treatment of colitis caused by Pythium insidiosum in a canine presenting haematochezia and progressive weight loss. Through imaging, a thickening of the transverse and descending colon was observed. Histopathological analysis of the large intestine fragment revealed the presence of hyphae, confirmed by immunohistochemistry and PCR as P. insidiosum. Antifungal treatment with itraconazole implemented after partial surgical resection, resulted in control of the disease.
A (in)elegibilidade de trabalhadores encaminhados ao Programa de Reabilitação Profissional do INSS
Authors: Santos Geovana de Souza Henrique dos , Lopes Roseli Esquerdo
Published: January 2016

Resumo Este estudo tem como objetivo investigar os motivos da não inclusão de trabalhadores contribuintes junto ao Programa de Reabilitação Profissional (PRP) do Instituto Nacional do Seguro Social, INSS. Lançando-se mão de um estudo de caso, transversal e documental, foram coletados dados dos prontuários dos sujeitos encaminhados ao PRP de uma Agência do INSS, da região Sudeste do Brasil, entre 2007 e 2012. Elaborou-se um instrumento para a referida coleta, para padronizar o registro dos dados, verificando-se nos pareceres finais acerca da Avaliação do Potencial Laborativo, redigidos pela equipe responsável pelo atendimento inicial, se o trabalhador encaminhado foi elegível ou não para integrar o PRP. Os motivos descritos pela equipe para a não inclusão dos trabalhadores foram agrupados segundo a proximidade quanto ao significado, formando categorias centrais, discriminando-se as justificativas de cada uma.
Territorialidade, casamentos mistos e política entre índios e portugueses
Authors: Moreira Vânia Maria Losada
Published: January 2016

RESUMO Na década de 1750, Pombal instituiu uma nova política metropolitana com relação aos índios, sancionando várias medidas para assimilá-los mais rapidamente ao mundo colonial. Dentre elas, destacam-se os incentivos aos enlaces matrimoniais mistos entre índios e portugueses; a abertura e disponibilização das terras indígenas ao aforamento; a imposição do uso da Língua Portuguesa e medidas para intensificar o comércio e as prestações de serviços aos portugueses. O objetivo do artigo é analisar como os índios da capitania do Espírito Santo lidaram com os novos desafios impostos pela política assimilacionista de Pombal, especialmente com a questão dos casamentos mistos e dos aforamentos, implementados com vistas a obter o controle sobre suas terras e a reprodução social de suas comunidades.
Level of physical activity and quality of life: a comparative study among the elderly of rural and urban areas
Authors: Barbosa Anderson Pedroso , Teixeira Tatiane Gomes , Orlandi Bianca , Oliveira Naiane Teixeira Bastos de , Concone Maria Helena Villas Boas
Published: January 2016

Objective : To investigate if the relationship between physical activity level (PAL) and quality of life (QOL) is affected by living environment (rural or urban). Method : A quantitative, observational and cross-sectional study was performed. Of the 40 participants of both genders, 20 were residents of urban areas and 20 were residents of rural areas in the town of Pimenta Bueno (RO), Brazil. The WHOQOL BREF and IPAQ Long Version questionnaires were used to assess QOL and PAL, respectively. Mann Whitney and Fisher's Exact were used to statistically compare groups for QOL and PAL scores. The correlation between the two was tested by the Spearman test. A significance level of p<0.05 was used. Results : No differences between the rural and urban areas for QOL or PAL were found. In the rural group a positive and significant correlation was found between PAL and the physical, psychological and complete QOL domains. In terms of PAL, elderly persons from the rural area who were regularly active had higher total QOL and physical domain scores than insufficiently active elderly individuals from the rural area. When place of residence was compared, insufficiently active elderly in the urban area had higher scores on the social component of QOL than insufficiently active elderly from the rural group. Among regularly active seniors, those living in the rural area had higher physical QOL scores. Conclusion : According to the results, level of physical activity exerts a differential influence on the QOL of elderly people from rural and urban areas.
Casa, rua, escola: gênero e escolarização em setores populares urbanos
Authors: Senkevics Adriano Souza , Carvalho Marília Pinto de
Published: January 2016

Este artigo deriva de pesquisa que buscou compreender o papel da socialização familiar na construção de trajetórias escolares diferenciadas por sexo, a partir do olhar de 25 crianças de camadas populares de uma escola municipal de São Paulo. Por meio de observações e entrevistas, obtiveram-se informações sobre a participação de meninas e meninos nos afazeres domésticos, nas práticas de lazer e na circulação pelo espaço público. Conclui-se que a socialização familiar tende a estimular um desempenho superior das meninas tanto pela construção de feminilidades pautadas por responsabilidade e disciplina, quanto pela significação positiva da escola enquanto um espaço de recreação e sociabilidade, em face das inúmeras restrições que as garotas sofrem no seu cotidiano na família, na casa e na rua.
Digital learning object for diagnostic reasoning in nursing applied to the integumentary system
Authors: Costa Cecília Passos Vaz da , Luz Maria Helena Barros Araújo
Published: January 2016

Objective: To describe the creation of a digital learning object for diagnostic reasoning in nursing applied to the integumentary system at a public university of Piaui. Method: A methodological study applied to technological production based on the pedagogical framework of problem-based learning. The methodology for creating the learning object observed the stages of analysis, design, development, implementation and evaluation recommended for contextualized instructional design. The revised taxonomy of Bloom was used to list the educational goals. Results: The four modules of the developed learning object were inserted into the educational platform Moodle. The theoretical assumptions allowed the design of an important online resource that promotes effective learning in the scope of nursing education. Conclusion: This study should add value to nursing teaching practices through the use of digital learning objects for teaching diagnostic reasoning applied to skin and skin appendages.
Academia, criação literária e temática lésbica: a produção de Lúcia Facco
Authors: Leal Virgínia Maria Vasconcelos
Published: January 2016

RESUMO A escritora Lúcia Facco destaca-se, com suas obras de ficção e ensaios acadêmicos, em um nicho específico e "marginal" do campo literário: a temática lésbica. O artigo analisa sua obra a partir da perspectiva de seu posicionamento político de promoção da visibilidade de sexualidades não hegemônicas.
URIC ACID AND TISSUE REPAIR
Authors: NERY Rodrigo Araldi , KAHLOW Barbara Stadler , SKARE Thelma L , TABUSHI Fernando Issamu , CASTRO Adham do Amaral e
Published: January 2016

Uric acid, a metabolic product of purines, may exert a role in tissue healing. In this review we will explore its role as an alarm initiating the inflammatory process that is necessary for tissue repair, as a scavenger of oxygen free radicals, as a mobilizer of progenitor endothelial cells and as supporter of adaptive immune system.
A saúde das crianças no mundo e no Brasil
Authors: Batista Filho Malaquias , Cruz Rachel de Sá Barreto Luna Callou
Published: January 2016

Resumo Os autores analisam o recente relatório do grupo intergeracional OMS (World Health Organization -WHO), Fundo das Nações Unidas para a Infância (UNICEF), Banco Mundial, consolidado pelas Nações Unidas, cobrindo o período 1990/2015, em relação aos compromissos e metas internacionais para a redução da mortalidade de menores de cinco anos no mundo. Trata-se de um "paper" histórico, correspondendo aos 25 anos da Declaração Universal dos Direitos das Crianças e dos Adolescentes, aos resultados de acordos internacionais firmados pelos chefes de estado na Reunião de Cúpula de Nova York (1990) e, em sequência, às Metas do Milênio, consensuadas por 195 países. O relatório destaca que apenas 62 países conseguiram cumprir o objetivo estipulado de reduzir a mortalidade em 2/3 (66,7%) sendo que o Brasil alcançou uma redução de 73% antes do prazo estabelecido, final de 2015. Os autores ressaltam a heterogenei-dade dos resultados obtidos no Brasil e no mundo, com uma grande diferença entre os espaços geográficos, com variações que se deslocam entre 5% a mais de 80%, atribuindo-se essas grandes diferenças às desigualdades de condições de vida que ainda prevalecem na maior parte dos países, inclusive no Brasil. O mais importante é que os êxitos alcançados são singulares na história nosográfica da humanidade.
The influence of attitudes toward physical activity and sports
Authors: Araújo Ana Tereza , Dosil Joaquín
Published: January 2016

Abstract Attitude is one of the most important predictor variables in relation to behavioral intentions regarding physical activity. Thus, this study aims to determine the influence of attitudes towards physical activity. The study comprised a sample of 1129 individuals (507 men and 622 women) age between 12 and 58 years ( = 18 sd = 4.03). To collect the data, the Scale of Attitudes Towards Physical Activity and Sports (Dosil, 2002) was based on the Portuguese version (Cid, Alves, & Dosil, 2008). The results show that attitudes towards physical activity and sports are more positive in younger male individuals, who do not attend higher education, who regularly engage in physical activity and whose parents engage in physical/sports activity themselves.
Correlational study of psychological variables self-confidence and anxiety
Authors: Campos Gloria González , Zagalaz Javier Cachón , Granados Santiago Romero
Published: January 2016

Abstract The purpose of this study is to analyze the concurrent validity of the psychological variables self-confidence and anxiety among the psychological measurement instruments: Psychological Characteristics Questionnaire related to Sports Performance (CPRD); Competitive State Anxiety Inventory-2 (CSAI-2); and Sports Psychological Inventory LOEHR. For this purpose, a correlational study was conducted between the selected variables and pertinent aspects of the measurement instruments. The study has revealed that the psychological variables self-confidence and anxiety are relevant in all three instruments, although not in all of the selected items.
Predictive power of task orientation, general self-efficacy and self-determined motivation on fun and boredom
Authors: Ruiz-González Lorena , Videra Antonio , Moreno-Murcia Juan Antonio
Published: January 2016

Abstract The aim of this study was to test the predictive power of dispositional orientations, general self-efficacy and self-determined motivation on fun and boredom in physical education classes, with a sample of 459 adolescents between 13 and 18 with a mean age of 15 years (SD = 0.88). The adolescents responded to four Likert scales: Perceptions of Success Questionnaire, General Self-Efficacy Scale, Sport Motivation Scale and Intrinsic Satisfaction Questionnaire in Sport. The results showed the structural regression model showed that task orientation and general self-efficacy positively predicted self-determined motivation and this in turn positively predicted more fun and less boredom in physical education classes. Consequently, the promotion of an educational task-oriented environment where learners perceive their progress and make them feel more competent, will allow them to overcome the intrinsically motivated tasks, and therefore they will have more fun. Pedagogical implications for less boredom and more fun in physical education classes are discussed.
Effect of surface roughness on the shaft resistance of non-displacement piles embedded in sand
Authors: Tehrani F. S. , Han F. , Salgado R. , Prezzi M. , Tovar R. D. , Castro A. G.
Published: January 2016

This paper presents the results of axial load tests performed on instrumented model piles pre-installed in a large-scale, half-circular chamber with a viewing window in its flat-side wall. Uniform silica sand samples were prepared with different densities using dry pluviation. The effects of pile surface roughness and soil density on the response of the soil during loading of the model piles were studied by analysing sequences of digital images using the digital image correlation technique. Test results show that the extent of the zone next to the pile that is affected by loading of the pile increases as the pile surface roughness and soil density increase. The development of a shear band next to the pile shaft was also studied by carefully analysing images taken with a digital microscope during loading of the model piles. The average thickness of the shear band is in the 3·2D50–4·2D50range for rough model piles, whereas no shear band was observed for smooth model piles. Understanding of shear band formation along the pile–soil interface provides insights into the calculation of the shaft resistance of the pile as a function of initial soil density and stress as well as pile surface roughness.
Perception of Intonational Patterns and Speaker’s Intentionality in English Yes-No Questions Produced by Brazilians
Authors: Passarella dos Reis Leonice , Gonçalves Alison Roberto , Silveira Rosane
Published: January 2016

Resumo: O presente estudo investigou a percepção de diferentes padrões entoacionais e da intencionalidade do falante em perguntas interrogativas totais do inglês. Os falantes foram seis brasileiros que gravaram um diálogo. Os ouvintes foram 31 brasileiros de diferentes partes do país que realizaram um Teste de Percepção da Modalidade da Sentença e um Teste de Percepção da Intencionalidade. Três contornos diferentes foram testados: padrão do inglês americano; padrão do português brasileiro; e padrão encontrado na interlíngua dos falantes. Os resultados demonstram que os padrões do inglês americano e do português brasileiro foram geralmente percebidos como interrogativas totais e percebidos inadequadamente como interrogativas WH. O padrão encontrado na interlíngua dos falantes foi na maioria das vezes percebido como interrogativas totais. O Teste de Percepção da Intencionalidade revelou que os ouvintes consideravam que os falantes faziam uso de interrogativas totais na maioria das vezes, o que parcialmente está de acordo com os resultados do teste de percepção. Não obstante, as intenções dos falantes foram interpretadas com muita variabilidade, o que pode ter sido um efeito do teste.Palavras-chave: percepção em L2; padrões entoacionais; interrogativas totais neutras; intencionalidade; fonologia da L2.Abstract: The current study investigated the perception of different intonational patterns and speaker’s intentionality in English yes-no questions produced by Brazilian Portuguese speakers of English. The speakers were six Brazilians who recorded a dialogue. The listeners were 31 Brazilians from different parts of the country who took a Perception of Sentence Modality Test and a Perception of Intentionality Test. Three different contours were tested: English-L1 like, Brazilian-Portuguese like, and Interlanguage like. Results demonstrate that English-L1 like and Brazilian-Portuguese like were generally perceived as yes-no and misperceived as wh-questions, whereas Interlanguage like tended to be mostly perceived as yes-no questions. In the Perception of Intentionality Test, there was a tendency for listeners to consider that the speakers were asking neutral yes-no questions most of the times, which somewhat is in tune with the results obtained at the perception test. Speakers’ intentions were also interpreted by listeners with much variability, which could have been a test effect.Keywords: L2 Perception; Intonational Patterns; Neutral Yes-No Questions; Intentionality; L2 Phonology.
Política económica e industria en Veracruz, México: definiciones, proyectos e incentivos fiscales, 1870-1915
Authors: Celaya Nandez Yovana
Published: January 2016

En el estado de Veracruz, el emprendimiento de un proyecto fabril que lograra el tránsito de una economía sostenida en el sector agrícola a un sector industrial fue un proceso de largo aliento en el siglo xix. En la historia de fracasos y éxitos destaca el periodo entre 1870 y 1910, donde algunas ciudades veracruzanas experimentaron el establecimiento y consolidación de unidades fabriles y talleres manufactureros. El objetivo de este texto es presentar una discusión desde el marco institucional del papel de los gobernadores y la legislatura en la definición de una política de incentivos tendente a favorecer el establecimiento de fábricas en el estado.
Apuestas para una economía diversificada: la inserción de la uva de Mendoza (Argentina) en mercados externos (1907-1930)
Authors: Rodríguez Vázquez Florencia
Published: January 2016

La economía provincial se caracterizó por la especialización en el monocultivo de vides y elaboración de vinos comunes para abastecer al mercado interno nacional (Litoral argentino). Sin embargo, desde las primeras décadas del siglo xx estuvo sujeta a crisis cíclicas, que alentaron las primeras propuestas para diversificar la agroindustria provincial. Entre ellas, resultaron notorias las iniciativas para comercializar uvas finas para consumo en fresco en los mercados internacionales. El objetivo de este artículo es estudiar los orígenes de la actividad, para ello reconstruiremos las trayectorias de los empresarios que incursionaron en forma temprana el sector, cuáles fueron las estrategias para posicionar la producción y analizaremos la participación de los agentes estatales implicados en el fomento y promoción de la actividad.
Volume 05 Index
Authors: Index GJS
Published: January 2016

 

Volume 05, Issue 1, (2015)

The effect of gender on refusal of suggestion in formal and informal situations among Iranian learners
 Behzad Rahbar, Mohammad Reza Oroji, Fariba Hedayatnejad
 01-13

Socio-economic impact of hydropower projects in Dzongu Region of North Sikkim

Binod Bhattarai 14-27

On family etiquette of Кazakhs on family etiquette of Кazakhs

Amanzhol Kalysh, Dinar Nuketayeva, Almagul Kanagatova, Zhuldyz Suleimenova, Seylbek Asanov Sadikovich, Zhuldyz Zhumashova
 28-33

Mapping and analysis of supply side policies in the alignment of education with industry in Indonesia
 Rakhma Oktavina, Ainul Haq
 34-40

 

Volume 05, Issue 2, (2015)

 

From the Editors

Dr. Mustafa Gündüz

 

The attention of the new public service in implementation of local autonomy bureaucracy in Indonesia

Titus Tandi Datu

42-53

 

Introducing Form-Function Theory Evidence from the Post Position “ra” and Focus Marker “ke” in Persian

Mohammadreza Oroji, Shidak Rahbarian

54-58
Comparison of anterior and posterior mini-implant-assisted maxillary incisor intrusion: Root resorption and treatment efficiency
Authors: Aras Isil , Tuncer Ali V.
Published: January 2016

Objective: 

To compare, through cone-beam computed tomography (CBCT), the root resorption and treatment efficiency of two different mini-implant-assisted modalities in intruding the maxillary incisors.

Materials and Methods: 

Thirty-two adults who had deep bite and elongated maxillary incisors were randomly allocated to two groups: anterior mini-implant group (AMG) and posterior mini-implant group (PMG). In the AMG, approximately 40 g of force was applied per side with elastic chains from mini-implants placed between the lateral incisors and canines and in the PMG, with beta-titanium wires from mini-implants placed between the second premolars and first molars. This study was conducted on CBCT scans taken before intrusion and after 4 months of intrusion. Data were analyzed by means of a paired t-test, independent t-test, and Pearson’s correlation test.

Results: 

One patient was excluded from the AMG due to mini-implant loosening. While the incisors showed a significant reduction in length and volume, this amount was greater in the AMG, especially in the central incisors (P < .05). Together with the mean intrusion rates of 0.62 and 0.39 mm/mo in the AMG and PMG respectively, the center of resistance of the incisors showed distal movement with labial tipping; these changes were greater in the PMG (P < .001). Volumetric root resorption was correlated with the amount of intrusion (P < .05).

Conclusions: 

Intrusion anchoring from posterior mini-implants is preferred in cases of upright incisors, as the use of such mechanics directs the roots into the spongiosa where they undergo less root resorption and more labial tipping.
Central Resistin/TLR4 Impairs Adiponectin Signaling, Contributing to Insulin and FGF21 Resistance
Authors: Benomar Yacir , Amine Hamza , Crépin Délphine , Al Rifai Sarah , Riffault Laure , Gertler Arieh , Taouis Mohammed
Published: January 2016

Adiponectin, an insulin-sensitizing hormone, and resistin, known to promote insulin resistance, constitute a potential link between obesity and type 2 diabetes. In addition, fibroblast growth factor (FGF)21 has effects similar to those of adiponectin in regulating glucose and lipid metabolism and insulin sensitivity. However, the interplay between adiponectin, FGF21, and resistin signaling pathways during the onset of insulin resistance is unknown. Here, we investigated whether central resistin promotes insulin resistance through the impairment of adiponectin and FGF21 signaling. We show that chronic intracerebroventricular resistin infusion downregulated both hypothalamic and hepatic APPL1, a key protein in adiponectin signaling, associated with decreased Akt-APPL1 interaction and an increased Akt association with its endogenous inhibitor tribbles homolog 3. Resistin treatment also decreased plasma adiponectin levels and reduced both hypothalamic and peripheral expression of adiponectin receptors. Additionally, we report that intracerebroventricular resistin increased plasma FGF21 levels and downregulated its receptor components in the hypothalamus and peripheral tissues, promoting FGF21 resistance. Interestingly, we also show that resistin effects were abolished in TLR4 knockout mice and in neuronal cells expressing TLR4 siRNAs. Our study reveals a novel mechanism of insulin resistance onset orchestrated by a central resistin-TLR4 pathway that impairs adiponectin signaling and promotes FGF21 resistance.
Next-Generation Sequencing Reveals That HLA-DRB3, -DRB4, and -DRB5 May Be Associated With Islet Autoantibodies and Risk for Childhood Type 1 Diabetes
Authors: Zhao Lue Ping , Alshiekh Shehab , Zhao Michael , Carlsson Annelie , Elding Larsson Helena , Forsander Gun , Ivarsson Sten A. , Ludvigsson Johnny , Kockum Ingrid , Marcus Claude , Persson Martina , Samuelsson Ulf , Örtqvist Eva , Pyo Chul-Woo , Nelson Wyatt C. , Geraghty Daniel E. , Lernmark Åke ,   for the Better Diabetes Diagnosis (BDD) Study Group
Published: January 2016

The possible contribution of HLA-DRB3, -DRB4, and -DRB5 alleles to type 1 diabetes risk and to insulin autoantibody (IAA), GAD65 (GAD autoantibody [GADA]), IA-2 antigen (IA-2A), or ZnT8 against either of the three amino acid variants R, W, or Q at position 325 (ZnT8RA, ZnT8WA, and ZnT8QA, respectively) at clinical diagnosis is unclear. Next-generation sequencing (NGS) was used to determine all DRB alleles in consecutively diagnosed patients ages 1–18 years with islet autoantibody–positive type 1 diabetes (n = 970) and control subjects (n = 448). DRB3, DRB4, or DRB5 alleles were tested for an association with the risk of DRB1 for autoantibodies, type 1 diabetes, or both. The association between type 1 diabetes and DRB1*03:01:01 was affected by DRB3*01:01:02 and DRB3*02:02:01. These DRB3 alleles were associated positively with GADA but negatively with ZnT8WA, IA-2A, and IAA. The negative association between type 1 diabetes and DRB1*13:01:01 was affected by DRB3*01:01:02 to increase the risk and by DRB3*02:02:01 to maintain a negative association. DRB4*01:03:01 was strongly associated with type 1 diabetes (P = 10−36), yet its association was extensively affected by DRB1 alleles from protective (DRB1*04:03:01) to high (DRB1*04:01:01) risk, but its association with DRB1*04:05:01 decreased the risk. HLA-DRB3, -DRB4, and -DRB5 affect type 1 diabetes risk and islet autoantibodies. HLA typing with NGS should prove useful to select participants for prevention or intervention trials.
Inhibition of Dipeptidyl Peptidase-4 Impairs Ventricular Function and Promotes Cardiac Fibrosis in High Fat–Fed Diabetic Mice
Authors: Mulvihill Erin E. , Varin Elodie M. , Ussher John R. , Campbell Jonathan E. , Bang K.W. Annie , Abdullah Tahmid , Baggio Laurie L. , Drucker Daniel J.
Published: January 2016

Dipeptidyl peptidase-4 (DPP4) inhibitors used for the treatment of type 2 diabetes are cardioprotective in preclinical studies; however, some cardiovascular outcome studies revealed increased hospitalization rates for heart failure (HF) among a subset of DPP4 inhibitor–treated subjects with diabetes. We evaluated cardiovascular function in young euglycemic Dpp4−/− mice and in older, high fat–fed, diabetic C57BL/6J mice treated with either the glucagon-like peptide 1 receptor (GLP-1R) agonist liraglutide or the highly selective DPP4 inhibitor MK-0626. We assessed glucose metabolism, ventricular function and remodeling, and cardiac gene expression profiles linked to inflammation and fibrosis after transverse aortic constriction (TAC) surgery, a pressure-volume overload model of HF. Young euglycemic Dpp4−/− mice exhibited a cardioprotective response after TAC surgery or doxorubicin administration, with reduced fibrosis; however, cardiac mRNA analysis revealed increased expression of inflammation-related transcripts. Older, diabetic, high fat–fed mice treated with the GLP-1R agonist liraglutide exhibited preservation of cardiac function. In contrast, diabetic mice treated with MK-0626 exhibited modest cardiac hypertrophy, impairment of cardiac function, and dysregulated expression of genes and proteins controlling inflammation and cardiac fibrosis. These findings provide a model for the analysis of mechanisms linking fibrosis, inflammation, and impaired ventricular function to DPP4 inhibition in preclinical studies.
Potato Consumption and Risk of Type 2 Diabetes: Results From Three Prospective Cohort Studies
Authors: Muraki Isao , Rimm Eric B. , Willett Walter C. , Manson JoAnn E. , Hu Frank B. , Sun Qi
Published: January 2016

OBJECTIVE

We aimed to elucidate whether potato consumption is associated with a higher risk of type 2 diabetes (T2D).

RESEARCH DESIGN AND METHODS

We analyzed data in three cohorts consisting of U.S. male and female health professionals without diabetes, cardiovascular disease, and cancer at baseline: 70,773 women from the Nurses’ Health Study (1984–2010), 87,739 women from Nurses’ Health Study II (1991–2011), and 40,669 men from the Health Professionals Follow-up Study (1986–2010). Potato consumption was assessed quadrennially using validated food frequency questionnaires (FFQs), and we calculated 4-year change in potato consumption from consecutive FFQs. Self-reported T2D diagnosis was confirmed using a validated supplementary questionnaire.

RESULTS

During 3,988,007 person-years of follow-up, 15,362 new cases of T2D were identified. Higher consumption of total potatoes (including baked, boiled, or mashed potatoes and french fries) was significantly associated with an elevated risk for T2D: the pooled hazard ratio (HR) of T2D compared with <1 serving/week was 1.07 (95% CI 0.97–1.18) for 2–4 servings/week and 1.33 (95% CI 1.17–1.52) for ≥7 servings/week after adjustment for demographic, lifestyle, and dietary factors. In addition, the pooled HRs of T2D for every 3 servings/week were 1.04 (95% CI 1.01–1.08) for baked, boiled, or mashed potatoes, and 1.19 (95% CI 1.13–1.25) for french fries. We further estimated that the HR of T2D was 0.88 (95% CI 0.84–0.91) for replacing 3 servings/week of total potatoes with the same amount of whole grains. Last, in comparison with stable potato consumption, every 3-servings/week increment of potato consumption in 4 years was associated with a 4% (95% CI 0–8%) higher T2D risk.

CONCLUSIONS

Greater consumption of potatoes, especially french fries, was associated with a higher T2D risk, independent of BMI and other risk factors. Replacement of potatoes with whole grains was associated with a lower T2D risk.
Risk Factors Associated With Severe Hypoglycemia in Older Adults With Type 1 Diabetes
Authors: Weinstock Ruth S. , DuBose Stephanie N. , Bergenstal Richard M. , Chaytor Naomi S. , Peterson Christina , Olson Beth A. , Munshi Medha N. , Perrin Alysa J.S. , Miller Kellee M. , Beck Roy W. , Liljenquist David R. , Aleppo Grazia , Buse John B. , Kruger Davida , Bhargava Anuj , Goland Robin S. , Edelen Rachel C. , Pratley Richard E. , Peters Anne L. , Rodriguez Henry , Ahmann Andrew J. , Lock John-Paul , Garg Satish K. , Rickels Michael R. , Hirsch Irl B. ,   for the T1D Exchange Severe Hypoglycemia in Older Adults With Type 1 Diabetes Study Group
Published: January 2016

OBJECTIVE

Severe hypoglycemia is common in older adults with long-standing type 1 diabetes, but little is known about factors associated with its occurrence.

RESEARCH DESIGN AND METHODS

A case-control study was conducted at 18 diabetes centers in the T1D Exchange Clinic Network. Participants were ≥60 years old with type 1 diabetes for ≥20 years. Case subjects (n = 101) had at least one severe hypoglycemic event in the prior 12 months. Control subjects (n = 100), frequency-matched to case subjects by age, had no severe hypoglycemia in the prior 3 years. Data were analyzed for cognitive and functional abilities, social support, depression, hypoglycemia unawareness, various aspects of diabetes management, C-peptide level, glycated hemoglobin level, and blinded continuous glucose monitoring (CGM) metrics.

RESULTS

Glycated hemoglobin (mean 7.8% vs. 7.7%) and CGM-measured mean glucose (175 vs. 175 mg/dL) were similar between case and control subjects. More case than control subjects had hypoglycemia unawareness: only 11% of case subjects compared with 43% of control subjects reported always having symptoms associated with low blood glucose levels (P < 0.001). Case subjects had greater glucose variability than control subjects (P = 0.008) and experienced CGM glucose levels <60 mg/dL for ≥20 min on 46% of days compared with 33% of days in control subjects (P = 0.10). On certain cognitive tests, case subjects scored worse than control subjects.

CONCLUSIONS

In older adults with long-standing type 1 diabetes, greater hypoglycemia unawareness and glucose variability are associated with an increased risk of severe hypoglycemia. A study to assess interventions to prevent severe hypoglycemia in high-risk individuals is needed.