bluuebunny/crossref_metadata_2025 huggingface dataset:
Printable devices for neurotechnology
Authors: Matta Rita , Moreau David , O’Connor Rodney
Published: February 2024

Printable electronics for neurotechnology is a rapidly emerging field that leverages various printing techniques to fabricate electronic devices, offering advantages in rapid prototyping, scalability, and cost-effectiveness. These devices have promising applications in neurobiology, enabling the recording of neuronal signals and controlled drug delivery. This review provides an overview of printing techniques, materials used in neural device fabrication, and their applications. The printing techniques discussed include inkjet, screen printing, flexographic printing, 3D printing, and more. Each method has its unique advantages and challenges, ranging from precise printing and high resolution to material compatibility and scalability. Selecting the right materials for printable devices is crucial, considering factors like biocompatibility, flexibility, electrical properties, and durability. Conductive materials such as metallic nanoparticles and conducting polymers are commonly used in neurotechnology. Dielectric materials, like polyimide and polycaprolactone, play a vital role in device fabrication. Applications of printable devices in neurotechnology encompass various neuroprobes, electrocorticography arrays, and microelectrode arrays. These devices offer flexibility, biocompatibility, and scalability, making them cost-effective and suitable for preclinical research. However, several challenges need to be addressed, including biocompatibility, precision, electrical performance, long-term stability, and regulatory hurdles. This review highlights the potential of printable electronics in advancing our understanding of the brain and treating neurological disorders while emphasizing the importance of overcoming these challenges.
Automated volumetric evaluation of intracranial compartments and cerebrospinal fluid distribution on emergency trauma head CT scans to quantify mass effect
Authors: Puzio Tomasz , Matera Katarzyna , Wiśniewski Karol , Grobelna Milena , Wanibuchi Sora , Jaskólski Dariusz J. , Bobeff Ernest J.
Published: February 2024

Background

Intracranial space is divided into three compartments by the falx cerebri and tentorium cerebelli. We assessed whether cerebrospinal fluid (CSF) distribution evaluated by a specifically developed deep-learning neural network (DLNN) could assist in quantifying mass effect.

Methods

Head trauma CT scans from a high-volume emergency department between 2018 and 2020 were retrospectively analyzed. Manual segmentations of intracranial compartments and CSF served as the ground truth to develop a DLNN model to automate the segmentation process. Dice Similarity Coefficient (DSC) was used to evaluate the segmentation performance. Supratentorial CSF Ratio was calculated by dividing the volume of CSF on the side with reduced CSF reserve by the volume of CSF on the opposite side.

Results

Two hundred and seventy-four patients (mean age, 61 years ± 18.6) after traumatic brain injury (TBI) who had an emergency head CT scan were included. The average DSC for training and validation datasets were respectively: 0.782 and 0.765. Lower DSC were observed in the segmentation of CSF, respectively 0.589, 0.615, and 0.572 for the right supratentorial, left supratentorial, and infratentorial CSF regions in the training dataset, and slightly lower values in the validation dataset, respectively 0.567, 0.574, and 0.556. Twenty-two patients (8%) had midline shift exceeding 5 mm, and 24 (8.8%) presented with high/mixed density lesion exceeding >25 ml. Fifty-five patients (20.1%) exhibited mass effect requiring neurosurgical treatment. They had lower supratentorial CSF volume and lower Supratentorial CSF Ratio (both p < 0.001). A Supratentorial CSF Ratio below 60% had a sensitivity of 74.5% and specificity of 87.7% (AUC 0.88, 95%CI 0.82–0.94) in identifying patients that require neurosurgical treatment for mass effect. On the other hand, patients with CSF constituting 10–20% of the intracranial space, with 80–90% of CSF specifically in the supratentorial compartment, and whose Supratentorial CSF Ratio exceeded 80% had minimal risk.

Conclusion

CSF distribution may be presented as quantifiable ratios that help to predict surgery in patients after TBI. Automated segmentation of intracranial compartments using the DLNN model demonstrates a potential of artificial intelligence in quantifying mass effect. Further validation of the described method is necessary to confirm its efficacy in triaging patients and identifying those who require neurosurgical treatment.
Advances and challenges in immunoPET methodology
Authors: Mohr Philipp , van Sluis Joyce , Lub-de Hooge Marjolijn N. , Lammertsma Adriaan A. , Brouwers Adrienne H. , Tsoumpas Charalampos
Published: February 2024

Immuno-positron emission tomography (immunoPET) enables imaging of specific targets that play a role in targeted therapy and immunotherapy, such as antigens on cell membranes, targets in the disease microenvironment, or immune cells. The most common immunoPET applications use a monoclonal antibody labeled with a relatively long-lived positron emitter such as 89Zr (T1/2 = 78.4 h), but smaller antibody-based constructs labeled with various other positron emitting radionuclides are also being investigated. This molecular imaging technique can thus guide the development of new drugs and may have a pivotal role in selecting patients for a particular therapy. In early phase immunoPET trials, multiple imaging time points are used to examine the time-dependent biodistribution and to determine the optimal imaging time point, which may be several days after tracer injection due to the slow kinetics of larger molecules. Once this has been established, usually only one static scan is performed and semi-quantitative values are reported. However, total PET uptake of a tracer is the sum of specific and nonspecific uptake. In addition, uptake may be affected by other factors such as perfusion, pre-/co-administration of the unlabeled molecule, and the treatment schedule. This article reviews imaging methodologies used in immunoPET studies and is divided into two parts. The first part summarizes the vast majority of clinical immunoPET studies applying semi-quantitative methodologies. The second part focuses on a handful of studies applying pharmacokinetic models and includes preclinical and simulation studies. Finally, the potential and challenges of immunoPET quantification methodologies are discussed within the context of the recent technological advancements provided by long axial field of view PET/CT scanners.
The composition of phenolic compounds in Chinese olive (Canarium album L.) cultivars and their contribution to the anti-inflammatory properties of the cultivars
Authors: He Fangqing , Du Yixuan , Pan Zhuangguang , Zeng Huize , Luo Haolin , Wang Junyi , Sun Yuanming , Li Meiying
Published: February 2024

Objective

This study aimed to explore the phenolic compounds (PCs) present in three Chinese olive (Canarium album L.) cultivars and the contribution of these PCs to the anti-inflammatory activities of the cultivars.

Methods

Ultra-high performance liquid chromatography coupled with hybrid quadrupole-orbitrap/mass spectrometry (UPLC-Q-Exactive/MS) was used to identify and quantify the PCs present in three Chinese olive cultivars, “Na zhong,” “Tan xiang,” and “Xiang zhong”. 2,2-diphenyl-1-picrylhydrazyl (DPPH); 2,2′-azinobis (3-ethylbenzothiazoline 6-sulfonate) (ABTS); and oxygen radical absorption capacity (ORAC) assays were used to assess the antioxidant activities of the PCs. Furthermore, we analyzed the anti-inflammatory action of these PCs using lipopolysaccharide (LPS)-induced RAW264.7 cells.

Results

A total of 44 PCs were identified in the three cultivars. Of these, 17 PCs were previously unidentified in Chinese olive. Among the cultivars, the free phenolics (FPs) of “Tan xiang” showed the strongest antioxidant activity. All cultivars have shown significant inhibition of TNF-α and IL-6 production. Clustering correlation analysis showed galloyl-bis-HHDP-glucose and paeonol have significant anti-inflammatory ability in FPs. Quininic, galloylquinic acid, 4-hydroxycinnamic acid and gallic acid hexoside have shown significant inhibition of IL-6 production in BPs. Furthermore, gallic acid, catechin, syringic acid, and nobiletin exhibit negative correlation in FPs and positive correlation in BPs of cytokine production, while corilagin and methyl ellagic acid pentoside exhibited opposite correlation.

Conclusion

In summary, this study contributed to the literature on PCs in Chinese olives and the potential health benefits of FPs and BPs.
The impact of opioid administration on the incidence of postanaesthetic colic in horses
Authors: Haralambus Rhea , Juri Michaela , Mokry Anna , Jenner Florien
Published: February 2024

Effective management of postoperative pain is essential to ensure patient welfare, reduce morbidity and optimize recovery. Opioids are effective in managing moderate to severe pain in horses but concerns over their adverse effects on gastrointestinal (GI) motility and associated increased colic risk limit their widespread use. Studies investigating the impact of systemic opioids on both GI motility and colic incidence in horses have yielded inconclusive outcomes. Therefore, this retrospective study aims to assess the influence of systemic administration of butorphanol, morphine, and methadone on post-anaesthetic colic (PAC) incidence. Horses undergoing general anaesthesia for non-gastrointestinal procedures that were hospitalized for at least 72 h post-anaesthesia were included in this study. Anaesthetised horses were stratified by procedure type into horses undergoing diagnostic imaging without surgical intervention, emergency or elective surgery. In addition, patients were grouped by opioid treatment regime into horses receiving no opioids, intraanaesthetic, short- (<24 h) or long-term (>24 h) postoperative opioids. Administered opioids encompassed butorphanol, morphine and methadone. The number of horses showing signs of colic in the 72 h after anaesthesia was assessed for each group. A total of 782 horses were included, comprising 659 undergoing surgical procedures and 123 undergoing diagnostic imaging. The overall PAC incidence was 15.1%. Notably, horses undergoing diagnostic imaging without surgery had a significantly lower PAC rate of 6.5% compared to those undergoing surgery (16.7%, p = 0.0146). Emergency surgeries had a significantly lower PAC rate of 5.8% compared to elective procedures (18%, p = 0.0113). Of the 782 horses, 740 received intraoperative opioids and 204 postoperative opioids, 102 of which long-term (≥24 h). Neither intraoperative (p = 0.4243) nor short-term postoperative opioids (p = 0.5744) increased PAC rates. Notably, only the long-term (≥24 h) administration of morphine significantly increased PAC incidence to 34% (p = 0.0038). In contrast, long-term butorphanol (5.3% PAC, p = 0.8482) and methadone (18.4% PAC, p = 0.6161) did not affect PAC rates. In summary, extended morphine administration was the only opioid treatment associated with a significantly increased risk of PAC.
Multi-center implementation of rapid whole genome sequencing provides additional evidence of its utility in the pediatric inpatient setting
Authors: Thompson Lauren , Larson Austin , Salz Lisa , Veith Regan , Tsai John-Paul , Jayakar Anuj , Chapman Rachel , Gupta Apeksha , Kingsmore Stephen F. , Dimmock David , Bedrick Alan , Galindo Maureen Kelly , Casas Kari , Mohamed Mohamed , Straight Lisa , Khan M. Akram , Salyakina Daria
Published: February 2024

Objective

Multi-center implementation of rapid whole genome sequencing with assessment of the clinical utility of rapid whole genome sequencing (rWGS), including positive, negative and uncertain results, in admitted infants with a suspected genetic disease.

Study design

rWGS tests were ordered at eight hospitals between November 2017 and April 2020. Investigators completed a survey of demographic data, Human Phenotype Ontology (HPO) terms, test results and impacts of results on clinical care.

Results

A total of 188 patients, on general hospital floors and intensive care unit (ICU) settings, underwent rWGS testing. Racial and ethnic characteristics of the tested infants were broadly representative of births in the country at large. 35% of infants received a diagnostic result in a median of 6 days. The most common HPO terms for tested infants indicated an abnormality of the nervous system, followed by the cardiovascular system, the digestive system, the respiratory system and the head and neck. Providers indicated a major change in clinical management because of rWGS for 32% of infants tested overall and 70% of those with a diagnostic result. Also, 7% of infants with a negative rWGS result and 23% with a variant of unknown significance (VUS) had a major change in management due to testing.

Conclusions

Our study demonstrates that the implementation of rWGS is feasible across diverse institutions, and provides additional evidence to support the clinical utility of rWGS in a demographically representative sample of admitted infants and includes assessment of the clinical impact of uncertain rWGS results in addition to both positive and negative results.
Human milk-derived versus bovine milk-derived fortifier use in very low birth weight infants: growth and vitamin D status
Authors: Lavassani Emmanuelle , Tauber Kate A. , Cerone Jennifer B. , Ludke Jennifer , Munshi Upender K.
Published: February 2024

Background

Human milk-derived fortifier (HMDF) coupled with human milk feeding in extremely premature infants reduces the adverse outcome risks of early exposure to bovine milk ingredients but may not provide enough nutrients for adequate catch-up growth compared with bovine milk-derived fortifier (BMDF).

Objective

This study aims to compare HMDF and BMDF effects on growth parameters and serum 25-hydroxy vitamin D (25OHD) levels in preterm very low birth weight (VLBW) infants during the first 8 weeks of life.

Methods

We present a retrospective chart review of inpatient VLBW infants with birth weight <1,500 g and gestational age <32 completed weeks who received either their mother’s milk or donor breast human milk fortified with HMDF or BMDF for the first 8 weeks. Weight, head circumference, length gain, and 25OHD level were calculated at 4 and 8 weeks of age.

Results

A total of 139 VLBW infants (91 HMDF + 48 BMDF) received fortified human milk without any supplemental premature formula from birth to 4 weeks of age, of whom 44 (37 HMDF + 7 BMDF) continued until 8 weeks of age. There was no statistically significant difference in the growth parameters between the two groups at 4 and 8 weeks of age. Serum 25OHD level in the HMDF group was significantly higher compared with that in the BMDF group at 4 weeks of age despite receiving lower vitamin D supplementation.

Conclusion

Similar gain in growth parameters in HMDF and BMDF groups at 4 and 8 weeks of age was observed, suggesting that HMDF provides adequate nutrients for growth in VLBW infants. A higher 25OHD level in HMDF may suggest better absorption.
Physical activity in metabolic syndrome
Authors: Chomiuk Tomasz , Niezgoda Natalia , Mamcarz Artur , Śliż Daniel
Published: February 2024

Obesity has become one of the global epidemics, contributing to the burden of disease in society, increasing the risk of diabetes, cardiovascular and liver diseases. Inadequate energy balance resulting from excessive energy intake and insufficient physical activity (PA) is one of the main factors contributing to the incidence of obesity and the development of metabolic syndrome (MetS). Treatment options for obesity include lifestyle modifications, pharmacotherapy and bariatric surgery, with the latter being the most effective treatment. Lifestyle interventions involving increased PA and reduced caloric intake improve metabolic outcomes. Early implementation of exercise leads to improved physical fitness, better glycemic control and lipid profile. Undertaking systematic PA is associated with better quality of life, improves insulin sensitivity, causes additional weight loss, reduces its adverse effects on bone mass and results in better body composition. In this narrative review we summarized the current state of knowledge on the impact of PA on the components of MetS and the latest recommendations for PA in patients with MetS.
Xylem plasticity of root, stem, and branch in Cunninghamia lanceolata under drought stress: implications for whole-plant hydraulic integrity
Authors: Li Shubin , Huang Xiaoyan , Zheng Ruping , Zhang Maxiao , Zou Zhiguang , Heal Kate V. , Zhou Lili
Published: February 2024

Introduction

A better understanding of xylem hydraulic characteristics in trees is critical to elucidate the mechanisms of forest decline and tree mortality from water deficit. As well as temperate forests and forests growing in arid regions, subtropical and tropical forests are also predicted to experience an increased frequency and intensity of climate change-induced drought in the near future.

Methods

In this study, 1-year-old Cunninghamia lanceolata seedlings (a typical subtropical species in southern China) were selected for a continuous controlled drought pot experiment of 45 days duration. The experimental treatments were non-drought (control), light drought, moderate drought and severe drought stress, which were 80%, 60%, 50%, and 40%, respectively of soil field maximum moisture capacity.

Results

The hydraulic conductivity, specific conductivity and water potential of roots, stems, and branches of C. lanceolata all decreased with the prolonging of drought in the different drought intensities. The relative decrease in these hydraulic values were greater in roots than in stems and branches, indicating that roots are more sensitive to drought. Root tracheid diameters normally reduce to ensure security of water transport with prolonged drought, whilst the tracheid diameters of stems and branches expand initially to ensure water transport and then decrease to reduce the risk of embolism with continuing drought duration. The pit membrane diameter of roots, stems and branches generally increased to different extents during the 15–45 days drought duration, which is conducive to enhanced radial water transport ability. The tracheid density and pit density of stems generally decreased during drought stress, which decreased water transport efficiency and increased embolism occurrence. Correlation analysis indicated that anatomical plasticity greatly influenced the hydraulic properties, whilst the relationships varied among different organs. In roots, tracheid diameter decreased and tracheid density increased to enhance water transport security; stems and branches may increase tracheid diameter and pit membrane diameter to increase hydraulic conductivity ability, but may increase the occurrence of xylem embolism.

Discussion

In summary, under drought stress, the xylem anatomical characteristics of C. lanceolata organs were highly plastic to regulate water transport vertically and radially to maintain the trade-off between hydraulic conductivity efficiency and safety.
Application of ethanol alleviates heat damage to leaf growth and yield in tomato
Authors: Todaka Daisuke , Quynh Do Thi Nhu , Tanaka Maho , Utsumi Yoshinori , Utsumi Chikako , Ezoe Akihiro , Takahashi Satoshi , Ishida Junko , Kusano Miyako , Kobayashi Makoto , Saito Kazuki , Nagano Atsushi J. , Nakano Yoshimi , Mitsuda Nobutaka , Fujiwara Sumire , Seki Motoaki
Published: February 2024

Chemical priming has emerged as a promising area in agricultural research. Our previous studies have demonstrated that pretreatment with a low concentration of ethanol enhances abiotic stress tolerance in Arabidopsis and cassava. Here, we show that ethanol treatment induces heat stress tolerance in tomato (Solanum lycopersicon L.) plants. Seedlings of the tomato cultivar ‘Micro-Tom’ were pretreated with ethanol solution and then subjected to heat stress. The survival rates of the ethanol-pretreated plants were significantly higher than those of the water-treated control plants. Similarly, the fruit numbers of the ethanol-pretreated plants were greater than those of the water-treated ones. Transcriptome analysis identified sets of genes that were differentially expressed in shoots and roots of seedlings and in mature green fruits of ethanol-pretreated plants compared with those in water-treated plants. Gene ontology analysis using these genes showed that stress-related gene ontology terms were found in the set of ethanol-induced genes. Metabolome analysis revealed that the contents of a wide range of metabolites differed between water- and ethanol-treated samples. They included sugars such as trehalose, sucrose, glucose, and fructose. From our results, we speculate that ethanol-induced heat stress tolerance in tomato is mainly the result of increased expression of stress-related genes encoding late embryogenesis abundant (LEA) proteins, reactive oxygen species (ROS) elimination enzymes, and activated gluconeogenesis. Our results will be useful for establishing ethanol-based chemical priming technology to reduce heat stress damage in crops, especially in Solanaceae.
The PGPR Bacillus aryabhattai promotes soybean growth via nutrient and chlorophyll maintenance and the production of butanoic acid
Authors: Mun Bong-Gyu , Hussain Adil , Park Yeon-Gyeong , Kang Sang-Mo , Lee In-Jung , Yun Byung-Wook
Published: February 2024

Plant growth-promoting rhizobacteria (PGPR) colonize plant roots, establish a mutualistic relationship with the plants and help them grow better. This study reports novel findings on the plant growth-promoting effects of the PGPR Bacillus aryabhattai. Soil was collected from a soybean field, PGPR were isolated, identified, and characterized for their ability to promote plant growth and development. The bacterium was isolated from the soybean rhizosphere and identified as B. aryabhattai strain SRB02 via 16s rRNA sequencing. As shown by SEM, the bacterium successfully colonized rice and soybean roots within 2 days and significantly promoted the growth of the GA-deficient rice cultivar Waito-C within 10 days, as well as the growth of soybean plants with at least six times longer shoots, roots, higher chlorophyll content, fresh, and dry weight after 10 days of inoculation. ICP analysis showed up to a 100% increase in the quantity of 18 different amino acids in the SRB02-treated soybean plants. Furthermore, the 2-DE gel assay indicated the presence of several differentially expressed proteins in soybean leaves after 24 hrs of SRB02 application. MALDI-TOF-MS identified β-conglycinin and glycinin along with several other proteins that were traced back to their respective genes. Analysis of bacterial culture filtrates via GCMS recorded significantly higher quantities of butanoic acid which was approximately 42% of all the metabolites found in the filtrates. The application of 100 ppm butanoic acid had significantly positive effects on plant growth via chlorophyll maintenance. These results establish the suitability of B. aryabhattai as a promising PGPR for field application in various crops.
Anhedonia and depression severity measures during ketamine administration in treatment-resistant depression
Authors: Kwaśny Aleksander , Cubała Wiesław Jerzy , Włodarczyk Adam
Published: February 2024

Background

Anhedonia is a core symptom of depression characterized by a diminished ability to experience pleasure. Currently available treatments for depression often fall short in adequately addressing anhedonia that often presents as a chronic and debilitating symptom. Ketamine is known to possess antianhedonic properties.

Methods

This post-hoc analysis of a naturalistic observational study of treatment-resistant depression inpatients (n=28) analyzed antianhedonic response patterns measured by Snaith-Hamilton Pleasure Scale and changes in Inventory of Depressive Symptomatology in responders (n=6) and non-responders (n=22) stratified per Montgomery-Åsberg Depression Rating Scale during short-term ketamine treatment.

Results

Results show that responders significantly improve in anhedonia over time (p=0.0084) and at the 7th infusion and follow-up (both p<0.05). Non-responders reported significant reduction in anhedonia over time (p=0.0011) and at the 5th, 7th infusion and at the follow-up (all p’s<0.05). Non-responders were also observed to improve significantly in self-reported depression at the 7th infusion (p=0.0219) but not at the follow-up.

Discussion

There is no complete overlap between change in depressive symptoms and anhedonia. Therefore, it might be assumed ketamine alleviates anhedonia as an individual symptom domain regardless of formal treatment outcome.
The dark side of mobile work during non-work hours: moderated mediation model of presenteeism through conservation of resources lens
Authors: Choi Woo-Sung , Kang Seung-Wan , Choi Suk Bong
Published: February 2024

Owing to the development of Information and Communication Technology (ICT) and the inevitability of telecommuting in the COVID-19 environment, the boundary between working and non-working hours has become blurred. mWork, that is, ICT-based off-hour work, which has increased through the pandemic, affects employees’ work attitudes, such as presenteeism. Hence, we designed a study to investigate the antecedents and mechanisms of employee presenteeism from the perspective of the conservation of resources theory. We supported our hypothesis using a sample of 325 Korean office workers obtained through three rounds of time-delay surveys. The results show that presenteeism is higher among employees with high mWork. In addition, employees’ mWork increases sleep deprivation and presenteeism, and the exchange ideology of employees reinforces the positive effect of sleep deprivation on presenteeism. Additionally, the higher the level of exchange ideology, the stronger the mediating effect of mWork on presenteeism through sleep deprivation. This study verified the conservation of resources theory by identifying the mechanism by which mWork affects an employee’s life, which in turn affects their work, and provides practical implications for managing productivity loss due to presenteeism.
Research on the identification and evolution of health industry policy instruments in China
Authors: Jin Jian , Du Hongbin
Published: February 2024

The application of health industry policies could be discovered more quickly and comprehensively through the automated identification of policy tools, which could provide references for the formulation, implementation, and optimization of subsequent policies in each province. This study applies the Bidirectional Encoder Representation from Transformer (BERT) model to identify policy tools automatically, utilizes Focal Loss to reduce the unbalance of a dataset, and analyzes the evolution of policy tools in each province, which contains time, space, and topic. The research demonstrates that the BERT model can improve the accuracy of classification, that supply and environment policy tools are more prevalent than demand tools, and that policy instruments are organized similarly in four major economic regions. Moreover, the policy’s attention to topics related to healthcare, medicine, and pollution has gradually shifted to other topics, and the extent of policy attention continues to be concentrated on the health service industry, with less attention paid to the manufacturing industry from the keywords of the various topics.
Sociological genealogy of a non-teleological concept of evolution
Authors: Beriain Josetxo , Gil-Gimeno Javier , Capdequí Celso Sánchez
Published: February 2024

The aim of this article is to carry out a sociological-conceptual genealogy of the evolutionist perspective (non-teleological) of approaching social reality. While during the first phases of modernity, a teleological and progressive conception of evolution was imposed, clearly manifested in the proposals of Auguste Comte or Herbert Spencer, in the last decades important bifurcations, processes, and developments have emerged that question the linearity and the finalist character of these positions. We consider that these approaches are closer to the nature of change and social phenomena, so it seems important to us to analyze some of the most outstanding contributions—in the form of sociological genealogy, as we have already mentioned—that have developed this perspective. In order to carry out our task, we have organized four sections: In the first, we make a critique of the sociological evolutionism represented by Comte, Spencer, and Parsons, focusing on the limits of their proposals and the blind spots associated with them. Second, we will analyze the anti-teleological cognitive approaches of Donald and the importance they attach to cultural transmission as a key element for understanding the evolution of both cognition and human societies. In a third moment, we will analyze the coexistence in Weber’s work between the dynamics of ‘disenchantment’ and ‘re-enchantment’ of the world in modern societies, understood as the two sides of the same coin that are in constant dynamic tension and that break with the evolutionary vision that goes from magic through religion to science, or from belief to knowledge. In a fourth moment, we analyze the relevance of approaches focused on what we have called ‘multiple evolutions’ (plural) that collide with each other—the conflicting simultaneity of the non-simultaneous—of their rhythms and directions, inspired by the works of Knöbl, Koselleck, Luhmann, Rosa, Eisenstadt, Abbott, and Zerubavel, which pave the way for the construction of a non-teleological approach to evolution.
Agricultural commodity futures prices prediction based on a new hybrid forecasting model combining quadratic decomposition technology and LSTM model
Authors: Zhang Tingting , Tang Zhenpeng
Published: February 2024

The stability of agricultural futures market is of great significance to social economy and agri-cultural development. In view of the complexity of the fluctuation of agricultural futures prices, it is challenging to make up for the shortcomings of the existing data preprocessing technology so as to improve the prediction accuracy of the model. This paper puts forward a new VMD-SGMD-LSTM model based on improved quadratic decomposition technology and artificial intelligence model. First of all, in the data preprocessing part, VMD is used to decompose the original futures price data, and SGMD is used to further process the remaining components. Secondly, the LSTM model is used to predict a series of modal components, and the final result is obtained by synthesizing the predicted values of different components. Furthermore, based on the futures trading data of wheat, corn and sugar in China agricultural futures market, this paper makes an empirical study in the 1-step, 2-step and 4-step ahead forecasting scenarios, respectively. The results show that compared with other benchmark models, the VMD-SGMD-LSTM hybrid model proposed in this paper has better forecasting ability and robustness for different agricultural futures, which effectively makes up for the shortcomings of existing research.
Normal variation of clinical mobility of the mandibular symphysis in cats
Authors: Minei Sergio , Auriemma Edoardo , Bonacini Serena , Kent Michael S. , Gracis Margherita
Published: February 2024

Introduction

The primary objective of this retrospective study was to document the normal variation of clinical mobility of the mandibular symphysis in cats and possible associations with bodyweight, age, sex, sexual status, breed and skull morphology. Secondarily, the radiographic appearance of the mandibular symphysis and possible associations with the analyzed data were evaluated.

Materials and methods

Two hundred and sixteen cats of 15 different breeds that underwent maxillofacial, oral and dental procedures from April 2015 to December 2021 were included. Clinical mobility was evaluated under general anesthesia using a 0 to 3 scale in lateromedial (LM) and dorsoventral (DV) directions. The symphysis was radiographically classified on the occlusal radiographic view of the rostral mandibles as fused or open, and with parallel or divergent margins.

Results

Bodyweight ranged from 2.2 to 12.5 kg (median 4.0 kg), age from 4 months to 17 years and 4 months (median 6 years and 4 months). At the first evaluation DV symphyseal mobility was 0 in 177 cases (82%), 1 in 32 cases (14.8%) and 2 in 7 cases (3.2%), LM mobility was 0 in 61 cases (28.3%), 1 in 110 cases (50.9%) and 2 in 45 cases (20.8%). 81.1% of the radiographs were included in the statistical analysis. Three symphyses (1.6%) were classified as fused and 190 (98.4%) as open, 129 (68.8%) having divergent margins and 61 (31.6%) parallel. One hundred and forty-eight cases (76.7%) did not show the presence of odontoclastic replacement resorption on the canine teeth (TR subgroup 1), 23 (11.9%) showed stage ≤3 lesions (TR subgroup 2) and 22 (11.4%) stage 4 lesions (TR subgroup 3). Logistic regression models exploring factors that affected DV and LM mobility were statistically significant (p < 0.0001; p < 0.0001) with an increase in LM mobility predicting an increase in DV mobility, and vice versa. An increase in DV mobility was associated with an increase in age and in having resorptive lesions. A decrease in LM symphyseal mobility was associated with being brachycephalic.

Conclusion

The great majority of cases showed some degree of LM symphyseal mobility, and 18% showed DV mobility. Symphyseal bony fusion is rare but possible.
Patient weight has diverse effects on the prescribing of different antibiotics to dogs
Authors: Becker Stuart D. , Hughes David M.
Published: February 2024

Introduction

Various factors including body weight-associated treatment cost may influence the probability of dispensing antibiotics to dogs in first-opinion practice, but their effect on specific drug choice remains unclear.

Methods

Multiple membership regression modeling was used to investigate the probability of dispensing 12 different antibiotics to dogs of different weights in the context of various disease presentations, using anonymized data obtained from electronic health records of 18 clinics between 2020 and 2022. Data from 14,259 dogs were analyzed.

Results

Treatment choice varied significantly with animal weight. Higher body weight was associated with an increased likelihood of dispensing lower cost antimicrobials such as amoxicillin and trimethoprim sulfonamide, while use of higher cost antimicrobials such as cefovecin was strongly biased to smaller animals. However, these effects were limited when restricted treatment options were available for the target condition.

Conclusion

This work demonstrates that anticipated financial costs may result in different treatment choices for canine patients depending on their body weight. Further work is needed to understand the impact of financial pressures on veterinarians’ treatment choices, and the implications for the optimization of antimicrobial stewardship in first opinion practice.
Small for Gestational Age Newborns in French Guiana: The Importance of Health Insurance for Prevention
Authors: Osei Lindsay , Vignier Nicolas , Nacher Mathieu , Laumonnier Juliette , Conan Claude , Clarke Loreinzia , Koivogui Akoï , Covis Sabrina , Valony Luciano , Basurko Célia , Wiedner-Papin Solène , Prual Alain , Cardoso Thierry , Leneuve-Dorilas Malika , Alcouffe Leslie , Hcini Najeh , Bernard Stéphanie , Succo Tiphanie , Vendittelli Françoise , Elenga Narcisse
Published: February 2024

Objectives: Small for gestational age (SGA) newborns have a higher risk of poor outcomes. French Guiana (FG) is a territory in South America with poor living conditions. The objectives of this study were to describe risk factors associated with SGA newborns in FG.

Methods: We used the birth cohort that compiles data from all pregnancies that ended in FG from 2013 to 2021. We analysed data of newborns born after 22 weeks of gestation and/or weighing more than 500 g and their mothers.

Results: 67,962 newborns were included. SGA newborns represented 11.7% of all newborns. Lack of health insurance was associated with SGA newborns (p < 0.001) whereas no difference was found between different types of health insurance and the proportion of SGA newborns (p = 0.86). Mothers aged less than 20 years (aOR = 1.65 [1.55–1.77]), from Haiti (aOR = 1.24 [1.11–1.39]) or Guyana (aOR = 1.30 [1.01–1.68]) and lack of health insurance (aOR = 1.24 [1.10–1.40]) were associated with SGA newborns.

Conclusion: Immigration and precariousness appear to be determinants of SGA newborns in FG. Other studies are needed to refine these results.
Quality Management and Corporate Governance of Romanian Industrial Companies Through Their Web-Based Communication
Authors: Bakos Levente Attila
Published: February 2024

Contemporary quality management is a more complex issue than first impressions might suggest. In order to continuously assure a certain quality level, it is necessary, albeit far from sufficient, to create optimal technical conditions. Some non-productive activities can also be crucial in quality assurance. We considered the quality manager and the manager for public relations/social responsibility to be of particular importance in this issue. In our research, we examine to what extent the two roles are present in some Romanian organizations. The research sample is 158 companies, of which 92 are companies showing outstanding performance at the national level, and 66 are predominantly small and medium-sized local companies from Transylvania. The data show that there is little difference between the two types of company in the area of social responsibility, while there is a significant difference in the case of corporate governance based on OECD principles. While, at local level, the quality assurance details are somehow hidden, or less visible due to some kind of indolence, the lack of corporate governance is obvious, the companies -if they apply these principles- show transparency, accountability.
Regional Perspective of Using Cyber Insurance as a Tool for Protection of Agriculture 4.0
Authors: Sitnicki Maksym W. , Prykaziuk Nataliia , Ludmila Humeniuk , Pimenowa Olena , Imbrea Florin , Șmuleac Laura , Pașcalău Raul
Published: February 2024

The digitalization of the agricultural industry is manifested through the active use of innovative technologies in all its areas. Agribusiness owners have to constantly improve their security to meet new challenges. In this context, the existing cyber risks of the agrarian industry were assessed and their classification by possible consequences, such as data theft or alteration, cyber terrorism, cyber warfare, software hacking or modification, the blocking of markets and transactions on them, was proposed. Cyber insurance is an effective tool for minimizing the likelihood of cyber incidents and for comprehensive post-incident support, with the involvement of cybersecurity specialists. An algorithm for cooperation between an agricultural company and an insurance company when concluding a cyber risk insurance contract is proposed, which takes into account the needs and wishes of insurers at each stage of the interaction. To assess the need to use cyber insurance in agriculture 4.0, a methodology has been developed to evaluate the regional characteristics of cybersecurity and the digitalization of agribusiness. The results of the study show a heterogeneous need for this tool in different regions of the world.
Study on the Impact of Cutting Platform Vibration on Stalk Cutting Quality in Industrial Hemp
Authors: Tian Kunpeng , Huang Jicheng , Zhang Bin , Ji Aimin , Xu Zhonghua
Published: February 2024

In response to the unclear impact of header vibration on cutting performance (stalk cutting quality and cutting energy consumption) during field operations of industrial hemp harvesters, this study utilized a vibration recorder to collect information on header vibration during the operation of industrial hemp harvesters. Through data processing, the dominant range for the resonant frequency and amplitude of the cutting platform is primarily concentrated between 5–45 Hz and 0–35 mm, respectively. Using numerical simulation techniques, a quadratic orthogonal rotation combination experiment was conducted with vibration frequency and amplitude as experimental factors and stalk cutting quality and cutting energy consumption as indicators. Regression equations were established to reveal the relationships between indicators and factors, elucidating the influence of each factor and its interactions on the indicators. Specifically, for the crack length indicator, the amplitude has a highly significant influence on the model, and there is a significant interaction effect between vibration frequency and amplitude on the model. As for the cutting energy consumption indicator, frequency and the interaction between frequency and amplitude significantly affect the model, while amplitude has an extremely significant impact on the model. Through comprehensive fuzzy evaluation, the optimal vibration parameter combination satisfying comprehensive cutting performance indicators was determined as a vibration frequency of 37.86 Hz and an amplitude of 5.34 mm. Furthermore, the reliability of the model has been further validated. This research can provide a reference for improving the field performance of industrial hemp harvesters.
Effects and Underlying Mechanisms of Rice-Paddy-Upland Rotation Combined with Bacterial Fertilizer for the Abatement of Radix pseudostellariae Continuous Cropping Obstacles
Authors: Lin Sheng , Yang Yuanyuan , Chen Ting , Jiao Yanyang , Yang Juan , Cai Zhaoying , Lin Wenxiong
Published: February 2024

Radix pseudostellariae is one of the well-known genuine medicinal herbs in Fujian province, China. However, the continuous cropping obstacles with respect to R. pseudostellariae have seriously affected the sustainable utilization of medicinal resources and the development of related industrial systems. The occurrence of continuous cropping obstacles is a comprehensive effect of multiple deteriorating biological and abiotic factors in the rhizosphere soil. Therefore, intensive ecological methods have been the key to abating such obstacles. In this study, four treatments were set up, i.e., fallow (RP-F), fallow + bacterial fertilizer (RP-F-BF), rice-paddy-upland rotation (RP-R), and rice-paddy-upland rotation + bacterial fertilizer (RP-R-BF), during the interval between two plantings of R. pseudostellariae, with a newly planted (NP) treatment as the control. The results show that the yield of R. pseudostellariae under the RP-F treatment decreased by 46.25% compared to the NP treatment. Compared with the RP-F treatment, the yields of the RP-F-BF, RP-R, and RP-R-BF treatments significantly increased by 14.11%, 27.79%, and 62.51%, respectively. The medicinal quality of R. pseudostellariae treated with RP-R-BF was superior to that achieved with the other treatments, with the total saponin and polysaccharide contents increasing by 8.54% and 27.23%, respectively, compared to the RP-F treatment. The ecological intensive treatment of RP-R-BF significantly increased the soil pH, content of organic matter, abundance of beneficial microbial populations, and soil enzyme activity, thus remediating the deteriorating environment of continuous cropping soil. On this basis, the ecological intensive treatment RP-R-BF significantly increased the activity of protective enzymes and the expression levels of genes related to disease and stress resistance in leaves and root tubers. Redundancy and Pearson correlation analyses indicated that rice-paddy-upland rotation improved the soil structure, promoted the growth of eutrophic r-strategy bacterial communities, enhanced compound oxidation and reduction, broke the relationship between the deteriorating environment and harmful biological factors, and eventually weakened the intensity of harmful factors. The subsequent application of bacterial fertilizer improved the beneficial biological and abiotic factors, activated various ecological functions of the soil, enhanced the ecological relationship between various biological and abiotic factors, and reduced the stress intensity of R. pseudostellariae, thereby improving its disease and stress resistance, and ultimately reflecting the recovery of yield and quality. The results indirectly prove that the intensive ecological amelioration of the soil environment was the main factor for the yield recovery of R. pseudostellariae under continuous cropping.
Lupine Cultivation Affects Soil’s P Availability and Nutrient Uptake in Four Contrasting Soils
Authors: Mori Alvez Cristina , Perdomo Varela Carlos , González Barrios Pablo , Bentos Guimaraes Andrea , del Pino Machado Amabelia
Published: February 2024

A substantial amount of phosphorus (P) in the soil is not readily available for plant uptake. Certain species may enhance P availability from poorly soluble P forms. This study focused on improving our comprehension of the effect of two lupine species (L. albus and L. angustifolius) on soil’s P mobilization and its link with soil acidity variations, comparing the response of the lupine species in terms of plant traits (i.e., aboveground biomass and nutrient uptake) with that of oats (Avena strigosa L.) in four contrasting soils (i.e., available P in soil, soil acidity, soil fertility, and texture). The phosphorus solubilization capacity was assessed on variations of P availability (PBray1) at four points in time, comparing soils with lupine to oat-containing soils and their baseline values. Compared to soils containing oats, at harvest, lupine soils had significantly increased PBray1 concentrations; the maximum average increment was around 5.3 mg kg−1, with L. albus in Sites 1 and 2, which presented higher organic matter (OM) contents than the other two sites. Lupine-induced soil acidification did not fully explain that P increase. Oats exhibited the highest increase in shoot dry weight in response to soil’s P availability, while lupine was the least affected. Nevertheless, L. albus showed similar or higher nutrient uptake than oats across all soils. The manganese (Mn) concentration was high in both lupine species’ shoot biomass; however, within each lupine species, across all soil types tested, these legumes had different Mn accumulation levels depending on the soil acidity. Lupinus albus had a higher ability to mobilize non-labile P in the light-textured soil with a high OM content, achieving comparable and higher plant P status than oats and providing N through biological N fixation (BNF), positioning it as a suitable crop for diversifying Uruguay’s agricultural crop rotation systems.