bluuebunny/crossref_metadata_2025 huggingface dataset:
Fome, comida e bebida na música popular brasileira: um breve ensaio
Authors: Vasconcelos Francisco de Assis Guedes de , Vasconcelos Mariana Perrelli , Vasconcelos Iris Helena Guedes de
Published: August 2015

O artigo reflete sobre como as temáticas fome, consumo de refrigerantes e consumo de feijão com arroz são enfocadas na música popular brasileira. Investigamos os anos de ditadura militar (1964-1985). O foco da análise é a chamada canção de protesto, gênero musical caracterizado por críticas estético-cultural, político-ideológica e social aos governos militares. Tomando como referencial teórico os estudos de ideologia e filosofia da linguagem de Mikhail Bakhtin, evidenciamos que a canção de protesto retratou elementos dos contextos econômico, político e social, e propiciou a difusão de hábitos e ideologias alimentares saudáveis ou não saudáveis, contribuindo para a construção da identidade alimentar brasileira.
Compaixão, piedade e deficiência física: o valor da diferença nas relações heterogêneas
Authors: Barsaglini Reni Aparecida , Biato Emília Carvalho Leitão
Published: August 2015

Analisam-se os sentimentos de compaixão e piedade diante da deficiência física, valendo-se da história do corpo anormal no Ocidente e das interpretações do sofrimento do Outro. Este corpo será alvo do Estado frente às mutilações bélicas e industriais. No século XIX, solicitam-se tolerância, compaixão e igualdade dos corpos em tensão com representações e práticas hierarquizantes das perfeições corporais e submetendo desvios a intervenções. Tais ambiguidades mobilizam sentimentos na confluência do individual/coletivo, do natural/sociocultural; podendo transmutar-se em virtude ou tecnologia de poder. A exegese do sofrimento pode implicar em generalizações e superficialidades enquanto que valorizar o singular e o oculto da experiência favorece a universalização da dignidade humana nas relações heterogêneas.
Produção documental de cientistas e a história da ciência: estudo tipológico em arquivos pessoais
Authors: Silva Maria Celina Soares de Mello e , Trancoso Márcia Cristina Duarte
Published: August 2015

Aborda o estudo da tipologia documental em arquivos pessoais de cientistas e sua importância para a pesquisa em história da ciência e para o trabalho do arquivista. Apresenta um breve histórico da diplomática à tipologia documental, enfatizando a identificação da atividade produtora do documento como fundamental para sua nomeação. Evidencia as características dos arquivos pessoais no que se refere à diversidade de tipos documentais e, em especial, os de físicos. Além disso, apresenta cinco exemplos de tipos documentais presentes em arquivos de físicos como exemplos da pesquisa em andamento e destaca a elaboração do glossário de espécies e tipos documentais presentes nos arquivos pessoais do Museu de Astronomia e Ciências Afins.
Fronteira, cana e tráfico: escravidão, doenças e mortes em Capivari, SP, 1821-1869
Authors: Lima Carlos A.M
Published: August 2015

Abordam-se as mortes e doenças de escravos no município canavieiro paulista de Capivari, associando as causas atribuídas a esses falecimentos ao contexto social e econômico e às características das comunidades escravas locais. Enfatiza-se o impacto da malária, relacionando-o às faixas etárias, ao ambiente criado pela lavoura canavieira e à evolução da ocupação do local, inicialmente fronteira expansiva. Explora-se o relacionamento entre doença e processos de trabalho, assim como a mortalidade pós-desembarque de africanos e a possibilidade de crises de mortalidade entre os cativos da cana. Os resultados conduzem à discussão sobre o impacto do habitat e dos deslocamentos e choques atlânticos.
Una batalla ganada: la eliminación de la poliomielitis en Cuba
Authors: Chaple Enrique Beldarraín
Published: August 2015

La poliomielitis fue introducida en Cuba a finales del siglo XIX por norteamericanos residentes en Isla de Pinos. Las primeras epidemias ocurrieron en 1906 y 1909, aumentaron en intensidad entre 1930-1958. El objetivo del artículo es reconstruir la historia de la enfermedad y sus epidemias en Cuba hasta 1961, de la primera Campaña Nacional de Vacunación Antipolio (1962) y de sus resultados, bien como analizar la continuidad de las campañas anuales de vacunación hasta la certificación de su eliminación (1994). Se siguió el método histórico lógico; se revisaron documentos de archivos, las estadísticas del Ministerio de Salud Pública sobre morbilidad y mortalidad hasta el 2000. Se calcularon tasas brutas de morbilidad y mortalidad. Se realizaron entrevistas a personajes claves.
Anatomical location of Periglischrus iheringi(Acari: Spinturnicidae) associated with the great fruit-eating bat (Chiroptera: Phyllostomidae)
Authors: Almeida Juliana , Serra-Freire Nicolau , Peracchi Adriano
Published: August 2015

Spinturnicid mites are ectoparasites that infest the wings of bats, and species of the genus Periglischrus Kolenati, 1857 are associated exclusively with bats of the family Phyllostomidae. We tested the hypothesis that a long-term evolutionary association led P. iheringi to choose very specific wing locations to infest the great fruit-eating bats, Artibeus lituratus. Seven anatomical wing regions and the uropatagium from 140 bats were analyzed and a total of 78 parasites were collected. Periglischrus iheringi had a significant preference for the plagiopatagium and dactylopatgium major wing regions (i.e., large, proximal regions) and infestation was directly correlated to area (r=0.9744). However, other factors may also influence mite choice, such as higher and more stable temperature and humidity, vascularization and lower risk of displacement.
Randomized Phase II Trial of Erlotinib Beyond Progression in Advanced Erlotinib-Responsive Non-Small Cell Lung Cancer
Authors: Halmos Balazs , Pennell Nathan A. , Fu Pingfu , Saad Shumaila , Gadgeel Shirish , Otterson Gregory A. , Mekhail Tarek , Snell Michael , Kuebler J. Philip , Sharma Neelesh , Dowlati Afshin
Published: August 2015

Background.

Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) therapy is clearly beneficial in patients with advanced EGFR-mutated non-small cell lung cancer (NSCLC). However, acquired resistance develops uniformly and the benefit of continuation of EGFR TKI therapy beyond progression remains unclear.

Materials and Methods.

This was a randomized phase II study of chemotherapy (arm A: pemetrexed or docetaxel) versus chemotherapy plus erlotinib (ERL) (arm B) in patients with progressive NSCLC following clinical benefit from erlotinib. In arm B, chemotherapy was given with erlotinib at an oral daily dose of 150 mg on days 2–19 of each cycle to minimize negative pharmacodynamic interactions. The primary endpoint was that continuation of erlotinib in this patient population could extend progression-free survival (PFS) by 50%.

Results.

A total of 46 patients were randomized (arm A: 24; arm B: 22). Patient characteristics were well balanced except there were more female patients in arm A (p = .075). The median PFS of patients in arm A was 5.5 months and for those in arm B, 4.4 months (p = .699). The response rates were 13% and 16% in arms A and B, respectively (p = .79). EGFR status data were available for 39 of the 46 patients and no significant difference in PFS was seen for continuing ERL beyond progression in mutation-positive patients. Substantially more toxicity was seen in arm B than arm A.

Conclusion.

There was added toxicity but no benefit with the continuation of ERL beyond progression along with chemotherapy as compared with chemotherapy alone.

Implications for Practice:

The benefits of continuing erlotinib upon progression alongside conventional chemotherapy are unclear. This randomized phase II study, initiated prior to the establishment of routine epidermal growth factor receptor (EGFR) mutation testing, addressed this clinically relevant issue through randomizing patients with prior clinical benefit from erlotinib (thereby enriching for EGFR-mutated tumors) upon progression in the second- or third-line setting to conventional chemotherapy (single-agent pemetrexed or docetaxel) with or without continued erlotinib. The results showed no benefit to continuing erlotinib beyond progression, while significantly more side effects were noted in the combination arm. Along with other recently presented study findings, these results argue against the routine practice of continuing erlotinib in this setting.
Challenges in the Diagnosis and Management of Well-Differentiated Neuroendocrine Tumors of the Lung (Typical and Atypical Carcinoid): Current Status and Future Considerations
Authors: Wolin Edward M.
Published: August 2015

Neuroendocrine tumors (NET) of the lung represent approximately 25% of all primary lung tumors and can be classified as low grade (typical carcinoids), intermediate grade (atypical carcinoids), or high grade (large cell neuroendocrine carcinoma or small cell lung carcinoma). Low- and intermediate-grade lung NET are increasingly recognized as biologically distinct from high-grade lung NET based on clinical behavior and underlying molecular abnormalities. This review summarizes current knowledge and challenges in the diagnosis and management of low- and intermediate-grade lung NET. Accurate histopathologic classification of lung NET is critical to determining appropriate treatment options but can be challenging even for experts. For low- and intermediate-grade lung NET, surgery remains the mainstay of treatment for localized disease. Although no standard systemic therapy has been established for the treatment of advanced, unresectable disease, a number of promising treatment options are emerging, including somatostatin analogs, temozolomide-based chemotherapy, targeted therapy with mammalian target of rapamycin or vascular endothelial growth factor inhibitors, and peptide receptor radionuclide therapy. Given the difficulty in accurately diagnosing these tumors, and the paucity of data supporting establishment of standard systemic therapy options, management of patients within the setting of a multidisciplinary team, including specialists with expertise in NET, is recommended. Ongoing and future clinical trials hopefully will provide stronger evidence to support treatment recommendations for low- and intermediate-grade lung NET.

Implications for Practice:

Treatment of neuroendocrine tumors (NET), particularly those of lung origin, continues to evolve. This review seeks to educate oncologists on the most up-to-date options and supporting data regarding management of two rare lung neoplasms, typical and atypical carcinoid tumors. Although surgical resection has been the mainstay of treatment, several systemic options have been studied in the treatment of NET of various origins that may potentially play a role in treating typical carcinoid tumors and atypical carcinoid tumors.
Unusual calvarial tumors
Authors: M Manoranjitha Kumari , P Manas Kumar , A Krishna Reddy
Published: August 2015

Hypophosphatemic mesenchymal tumors of the skull bone otherwise known as oncogenic osteomalacia and aneurysmal bone cysts of the skull are rare tumors occurring in calvaria. This report consist two rare tumors recently encountered in the Department of Neurosurgery, KIMS Hospital, Secunderabad. Both the patients presented with different clinical pictures. A middle aged person with hypophosphatemic mesenchymal tumor presented with generalized weakness, tremors, pains and fracture left hip joint associated with scalp swelling with hypocalcemia and hypophosphatemia. The other patient with aneurysmal bone cyst was a child and presented with progressive painless enlargement of swelling in the parietal region. Both the tumors were locally aggressive though they were benign histopathologically. Both the patients underwent surgical excision of the tumor. Complete surgical excision reverted the biochemical and clinical picture of the hypophosphatemic mesenchymal tumor patient to normal level. Oncogenic osteomalacia and aneurysmal bone cysts are rare tumors to occur in calvaria, operation is reasonably an easy procedure and complete excision of the tumor will cure the problem. Keywords: unusual calvarial tumors; hypophosphatemic mesenchymal tumors; oncogenic osteomalacia
Adult-onset Still’s disease
Authors: V Srinivas , SV Chandra Mouli , S Sravan Kumar
Published: August 2015

A 24-year-old male presented with fever, sore throat, and arthralgias for duration of 4 weeks. Fever was high grade, intermittent, associated with maculopapular rash. He was admitted in outside hospital and was started on antibiotics, antituberculosis treatment (ATT), and anti-malarials. The patient was discharged without any improvement. He was then admitted in KIMS hospital, Secunderabad, with persistence of initial symptoms and he was investigated thoroughly for all possible infections, malignancies and autoimmune disease. Rheumatologist consultation was taken, Adult-onset Still’s disease (AOSD) has been considered as he fulfilled the criteria of AOSD. He was started on appropriate therapy and was discharged in stable condition. Keywords: Adult-onset Still’s disease; maculopapular rash; systemic inflammatory disorder
Complete androgen insensitivity syndrome: Case based review article
Authors: H Babulreddy
Published: August 2015

Complete androgen insensitivity syndrome (CAIS) a form of 46 XY disorder of sex development (DSD), usually presents with an inguinal hernia in an infant or a child and with primary amenorrhea in adult phenotypic female. We hereby report a case who reared as a female presented to us with primary amenorrhea and on further evaluation, diagnosed to have CAIS, then we also discuss in detail about this rare entity. Keywords: complete androgen insensitivity syndrome; primary amenorrhea; gonadectomy
Synchronous double malignancy: Acute lymphoblastic leukemia and carcinoma rectum
Authors: K Meher Lakshmi , B Triveni , S Sai Mallikarjun , S Sree Lakshmi
Published: August 2015

Synchronous double malignancy involving hematopoietic system and solid organs is rare. We report an interesting case of acute lymphoblastic leukemia (ALL) and carcinoma rectum. High index of suspicion is required in leukemic patients with bleeding per rectum to diagnose synchronous malignancy at an early stage. Keywords: double malignancy; carcinoma rectum; acute lymphoblastic leukemia; synchronous malignancy
Imaging spectrum in Brodie’s abscess
Authors: Subbarao Kakarla
Published: August 2015

Not available
Effects of aerobic exercise training in animal models of hypertension.
Authors: Palma Renata Kelly da , Malfitano Christiane , Shimojo Guilherme Lemos , Sanches Iris Callado , Angelis Kátia De
Published: August 2015

Background: Hypertension is one of the leading causes of death due to stroke, heart attack and kidney failure. The understanding of the pathophysiological mechanisms involved in its development and maintenance is critical to potential therapeutic interventions. Thus, animal models of hypertension have been used in the study of this disease for many years. Objective: To investigated the effects of dynamic aerobic exercise training as a non- pharmacological approach for the management of hypertension in animal models. Method/Design: This study is a literature review conducted in the Medline database. Results: The results demonstrated that aerobic exercise training may reduce blood pressure in different rat models of hypertension. Conclusions: The dynamic aerobic exercise can reduced blood pressure in different animal models of hypertension by mechanisms that involving neurohumoral changes, reinforcing the important role of this approach in the treatment of hypertension and its associated disorders.
Effect of Addition of Concentrated Proteins and Seminal Plasma Low Molecular Weight Proteins in Freezing and Thawing of Equine Semen
Authors: Fagundes Bruno , Van Tilburg M F , Souza G V , Caiado J.R.C , Barreto M.A.P , Silva J.F.S
Published: August 2015

Difficulties in obtaining equine frozen semen with potential fertility are recognized. This study was designed to investigate the effect of seminal plasma on frozen/thawing of eight stallion semen from different breed using the following treatments: Seminal plasma with ten-fold concentrated proteins with molecular weight above 10 kDa on frozen extender; Part of seminal plasma with proteins under 10 kDa on frozen extender; Conventional freezing, using whole seminal plasma on frozen extender. Using the parameter of 30% of seminal motility post-thawing as index of good freezability, it was verified an increased percentage of stallions that presented good freezability when semen was frozen with seminal plasma containing ten-fold concentrated proteins with molecular weight above 10 kDa on frozen extender. These results, suggested the use of seminal plasma concentrated proteins from own stallion to freezing/thawing semen.
Importância do Consentimento Informado na Oncologia
Authors: Mourthé Ayla Martins Ramos , Melo Débora Rosmaninho Coutinho , Gonçalves Paula Fontes Passalini , Cabral Rachel Boechat , Cabral Hildeliza Lacerda Tinoco Boechat
Published: August 2015

A partir da Declaração Universal dos Direitos Humanos todos os estados democráticos incluem em suas constituições o princípio da dignidade da pessoa humana. No Brasil não foi diferente. Este princípio, alçado à categoria de valor pelo ordenamento jurídico brasileiro passa a reclamar uma tutela dos direitos relativos à pessoa – os direitos da personalidade – muito exigente. Nessa esteira, o presente artigo objetiva demonstrar que o consentimento informado ganha especial relevo, devendo o médico sempre explicar à pessoa a respeito do tratamento ou cirurgia, com detalhes para que esta possa consentir na atuação em sua esfera psicofísica. Pretendeu-se assinalar a importância do consentimento informado na atual perspectiva da proteção à dignidade humana e os direitos a ela inerentes, principalmente na oncologia, casos em que há doenças incuráveis ou de rara probabilidade de cura.
Effect of Magnetic Field and Temperature on the Exchange Bias in Phase-Separated Nd1-xSrxCoO3(x=0.10, 0.15)
Authors: Yang Yi-Yun
Published: August 2015

The exchange bias phenomena of phase-separated Nd1-xSrxCoO3(x=0.10, 0.15) samples were systematically
investigated in this paper. The samples were prepared using conventional solid state reaction method. When the NdSrCoO samples cooled down in magnetic field below freezing temperature, the hysteresis loops shifted along the
magnetic field axis. Moreover, exchange bias of Nd1-xSrxCoO3 is strongly dependent on the field and the temperature. The
influence of magnetic field on the relative ratio of the coexisting phases may be responsible for these behaviors.
Therefore, our study confirmed that in phase-separated system, the exchange coupling at the interface between the
ferromagnetism clusters and the spin glass regions may induce interfacial exchange anisotropy.
Effects of Composite Catalyst Co2B/TiO2 on Hydrolysis of NaBH4
Authors: Li Yong , Zhang Yuxin , Gu Yuxi , Cai Yufei , Zhang Ruizhu , Zheng Xueping
Published: August 2015

For the purpose of improving hydrogen release capacity of NaBH4, hydrogen generation performance of
NaBH was catalyzed by Co2B and TiO2 compound with different mole ratio and percentage composition are investigated.
The experiment mainly concentrated in the hydrogen generation rate and the hydrogen generation volume. The results
indicate that the effects of hydrogen release of NaBH when the proportions and amount of Co2B/TiO2 are not obvious.
Changing the proportions and the amount, the amount of hydrogen release by hydrolysis of NaBH4 are between 343-
375ml. However, the study on the rate of hydrogen release finds that the effects of the proportion and amount of the
compound catalyst on the rate of hydrogen release are very marked. The rate of hydrogen release of the catalyst samples
presents an obvious increase when the amount of Co2B/TiO2 is between 1-4%. Among all the samples of compound
catalyst, the rate of hydrogen release of the sample with 5% Co2B/2TiO2 is the largest.
DC Side Ripple Voltage Analysis and Fuzzy PI Control Strategy Research for APF
Authors: Wu Ting , Yang Jian-Feng , Miao Qing
Published: August 2015

Owing to the problems of DC side capacitor value choice in the application of Active Power Filter (APF), this
article presents a technique based on the analysis of the ripple voltage in DC side by graining appropriately the undulation
control rate within the range of settings and control DC voltage so that the voltage fluctuation rate can reach minimum
value under the condition of specific capacitance which is aimed at getting good compensation effects. In order to achieve
the stability of the DC side capacitor voltage control, we introduce a new technique on the DC output voltage deviation
square values of adaptive fuzzy PI control. Meanwhile, a Space Vector Pulse Width Modulation (SVPWM) is used to
conduct optimization design for the DC side voltage waveform. The simulation results show that using this method reduces
the DC voltage ripple and achieves steady DC output voltage.
Deformation Analysis of 128×128 Infrared Detector with Reticulated InSb Pixel Array
Authors: Zhang Xiaoling , Liu Yawei , Zhang Liwen , Meng Qingduan
Published: August 2015

The reticulated InSb pixel array was successfully employed in the design of large format InSb infrared focal
plane arrays (IRFPAs) detector, to remove the thermal strain accumulated in InSb IRFPAs with the thermal shock test. In
order to explore the deformation rules in the InSb IRFPAs with reticulated InSb pixel array, in light of the proposed
equivalent modeling, a three-dimensional modeling of InSb IRFPAs is created, and the Z-component of strain is selected
to compare the displacements in the various layers of InSb IRFPAs. Analyzing results that show the top surface deformation
of InSb IRFPAs originates from the thermal mismatch between the silicon readout integrated circuit (ROIC) and
the indium bump array directly above. After passing through the intermediate layer and the silicon substrate, the deformation
amplitude along Z-direction is reduced firstly from 0.113 μm to 0.0395 μm, finally to 0.0042 μm. Here the intermediate
layer is made up of the indium bump array and the reticulated InSb pixel array. These deformation data suggest
that the InSb IRFPAs with reticulated InSb pixel array is superior to that designed with the underfill filled structure in the
fabricating large format InSb IRFPAs.
Application of Comprehensive Landing Method During the Rectification for the Brick-concrete Buildings in Soft Soil Area
Authors: Xiao-nan Zhang , San-yuan Shi , Xiao-lei Wang , Hong-yu Zhao
Published: August 2015

This paper first analyzes the tilting reasons of a brick-concrete building in Yunnan province in China. Then, a comprehensive rectification method which combines the stress release method and the excavation of stress release trench was put forward. This method uses the anchor static pile in order to guarantee the safety of the building in the process of rectifying. The practice case showed that the inclination rate of the building returned to 3 % from 14.4 %, which proved the efficiency of the proposed method.
Seismic Performance Evaluation of Boil-Off Gas Compressor in LNG Terminal
Authors: Park Hyo-Sang , Lee Tae-Hyung
Published: August 2015

Liquefied natural gas (LNG) terminals, one of the lifeline facilities, need to be protected by a proper seismic
design against extreme earthquakes. An LNG terminal consists of a series of process facilities that are connected by pipelines
of various sizes. Boil-off gas (BOG) compressor is one of the critical process facilities whose failure will cause the
functional failure of the LNG terminal. Process facilities, including BOG compressor, other than LNG storage tanks and
pipes, have not been a major concern in terms of the seismic performance evaluation. In this study, the seismic performance
of a BOG compressor is evaluated and the seismic fragility functions are presented. An integrated system of a BOG
compressor is modeled by a 3 dimensional finite element modeling scheme. A series of time history analyses are conducted
to monitor the behavior of anchor bolts, one of the most critical elements in the BOG compressor. To develop fragility
curves, a set of 20 ground motions are selected from a database of the historic earthquake accelerations. Fragility
curves are developed based on the maximum likelihood estimation approach with respect to the strength limit states.
When an earthquake load is applied to the BOG compressor, the main motor is likely to overturn and the flywheel is
likely to slide, and, consequently, anchor bolts will be subjected to tension and shear force, respectively. It is concluded
that the BOG compressor is safe against the design level earthquake
A New ANFIS Model based on Multi-Input Hamacher T-norm and
Subtract Clustering
Authors: Zhang Feng-Yi , Liao Zhi-Gao
Published: August 2015

This paper proposed a novel adaptive neuro-fuzzy inference system (ANFIS), which combines subtract
clustering, employs adaptive Hamacher T-norm and improves the prediction ability of ANFIS. The expression of multiinput
Hamacher T-norm and its relative feather has been originally given, which supports the operation of the proposed
system. Empirical study has testified that the proposed model overweighs early work in the aspect of benchmark Box-
Jenkins dataset and may provide a practical way to measure the importance of each rule.
Experimental Fusion of Contrast Enhanced High-Field Magnetic Resonance Imaging and High-Resolution Micro-Computed Tomography in Imaging the Mouse Inner Ear
Authors: S Allen Counter , Damberg Peter , Aski Sahar Nikkhou , Nagy Kálmán , Berglin Cecilia Engmér , Laurell Göran
Published: August 2015

Objective:

Imaging cochlear, vestibular, and 8th cranial nerve abnormalities remains a challenge. In this study, the membranous and osseous labyrinths of the wild type mouse inner ear were examined using volumetric data from ultra high-field magnetic resonance imaging (MRI) with gadolinium contrast at 9.4 Tesla and high-resolution micro-computed tomography (µCT) to visualize the scalae and vestibular apparatus, and to establish imaging protocols and parameters for comparative analysis of the normal and mutant mouse inner ear.

Methods:

For in vivo MRI acquisition, animals were placed in a Milleped coil situated in the isocenter of a horizontal 9.4 T Varian magnet. For µCT examination, cone beam scans were performed ex vivo following MRI using the µCT component of a nanoScan PET/CT in vivo scanner.

Results:

The fusion of Gd enhanced high field MRI and high-resolution µCT scans revealed the dynamic membranous labyrinth of the perilymphatic fluid filled scala tympani and scala vestibule of the cochlea, and semicircular canals of the vestibular apparatus, within the µCT visualized contours of the contiguous osseous labyrinth. The ex vivo µCT segmentation revealed the surface contours and structural morphology of each cochlea turn and the semicircular canals in 3 planes.

Conclusions:

The fusion of ultra high-field MRI and high-resolution µCT imaging techniques were complementary, and provided high-resolution dynamic and static visualization of the complex morphological features of the normal mouse inner ear structures, which may offer a valuable approach for the investigation of cochlear and vestibular abnormalities that are associated with birth defects related to genetic inner ear disorders in humans.
Current and Future Applications of Distributed Acoustic Sensing as a New
Reservoir Geophysics Tool
Authors: Li Meng , Wang Hua , Tao Guo
Published: August 2015

Distributed Acoustic Sensing (DAS) is a novel technique with low cost, no production deferment,
complete coverage and repeatability for seismic data acquisition in vertical seismic profile (VSP), hydraulic
fracturing monitoring, well and reservoir surveillance and micro-seismic detection. In this paper, we give a review
on the field applications of DAS and the corresponding pre-processing methods as well as the limitations
that hinder its further applications in exploration and production. Finally, future developments for DAS are
discussed, including the enhancement of S/N ratio, precise determination of receiver channels in depth, rapid
processing of massive data and integrated interpretation of multi-mode optical fiber.
Study on Reservoir-caprock Assemblage by Dual Logging Parameter
Method
Authors: Xu Jingling , Liu Luofu , Xiao Fei , Zou Changchun , Li Hao , Wang Yuanzheng , Wang Ying
Published: August 2015

Generally, logging curve shape and logging data are used to identify and evaluate the reservoir and caprock in
the study of reservoir-caprock assemblage in conventional logging method, which fails to distinguish the reservoircaprock
assemblage and allocation relation of different producing layers (high and low production gas layer, dry layer). In
order to analyze and discriminate the types of reservoir-caprock assemblage and the corresponding productivity quickly
and accurately, the dual logging parameter method is put forward to study reservoir-caprock assemblage and predict its
productivity. Besides, discrimination standard and allocation relationship of reservoir-caprock assemblage determined by
the dual parameters of reservoir porosity and caprock porosity are also established.
Feasibility Study of While-drilling Data Transmission Technology Based
on Radio Frequency Identification
Authors: Ni Wei-Ning , Li Ji-Bo , Li Shan-Guo , Zhang Wei
Published: August 2015

Downhole data transmission methods based on mud-pulse and low-frequency electromagnetic waves can’t satisfy
the need of large amount and high speed data uploading during drilling. In this paper, a novel data transmission technique
based on releasing RFID tags by LWD tools is designed and validated. As the memory and transmission media,
RFID tags are pre-mounted tactfully in cavities of the downhole releasing tool which can transmits/write LWD data to
these tags. By releasing regularly or irregularly into the annulus fluids, RFID tags can be carried to the surface by mud
circulation. To finish data transportation function, LWD data can be read out on the surface. Wireless charging high capacity
(1Mbits) RFID tags are designed, which contains microprocessor and memory, to expand the storage capacity of
RFID tags. The power supply for microprocessor and memory in the tag is electromagnetic waves from RF Reader/Writer
module. The equivalent data transmission speed of this system can be up to 278 bit/s (1 tag/h is assumed), which is more
much faster than the traditional mud pulser (<10 bit/s).
Predicting the Relative Permeability of Water Phase Based on Theory of
Coupled Electricity-Seepage and Capillary Bundle Model
Authors: Ge Xinmin , Fan Yiren , Xing Donghui , Chen Jingying , Cong Yunhai , Liu Lailei
Published: August 2015

An analytical water relative model based on the theory of coupled electricity-seepage and capillary bundle pore
structure is described. The model shows that the relative permeability of water is affected by two kinds of parameters,
which are depicted as static parameters and dynamic parameters. Revised Kozeny-Carman equation and Archie formulas
are introduced to deduce the model, which enhance the characterization ability of pore structure. Two displacing states,
where we summarized that oil coats capillary walls and oil occupies capillary centers are also discussed for optimization
of the model. In contrast to existing empirical formulas where relative permeability is strongly related to capillary pressure
and fractal dimension, we introduce only water saturation and saturation index as input parameters, which make the
model simpler to use. Petrophysics and unsteady relative permeability experiments (oil displacing water) are carried out to
testify the two models. The fitting results show that for oil displacing experiments presented in this paper, the displacing
state where oil coats capillary walls is suitable to predict the relative permeability of water.
Logging Evaluation Method for Pore Pressure of Shale Gas Reservoirs-
Taking Fuling Area, Sichuan Basin as an Example
Authors: Shibo Hao , Wujun Jin
Published: August 2015

Unconventional oil and gas resources, especially shale gas resources have great potential for exploration and
development in China. In Shale gas exploration and development process, reservoir pore pressure is a very important parameter,
and the pore pressure prediction can improve the appraisal accuracy of project dessert. This paper analyzes several
formation pore pressure calculation methods based on logging data, and optimized the “Equivalent depth method”.
The preliminary results show that this method can carry out the accurate evaluation on the abnormal high pressure of the
shale gas reservoirs of Fuling area with high calculation precision and application potential.
Study on the Influence of Urban Rail Transit on the Value of Real Estate Based on Information System
Authors: Lichao Jiao
Published: August 2015

Urban rail transit has strong transportation capability, but little environmental pollution. Besides, it also saves
land resource. These advantages make the urban rail transit gradually becomes an effective measure to solve city traffic
problems. In order to analyze the impact of the scope and extent of urban rail transit on the real estate, this paper first introduces
the composition of real estate market information system, explains the process of how the urban rail transit influences
the value of real estate by taking the 1st project of line 1 of Zhengzhou urban rail transit in Henan province for example,
finds the semi logarithmic model which has the best regression effects with three hedonic price models and the
collected data from the real estate market information system, and finally works out the added value of real estate generated
by the above urban rail transit.
Study on Low-carbon Urban Development Path and Strategy Based on Principal Components Analysis
Authors: Hongping Wang , Tianbao Su , Hailing Sun
Published: August 2015

Scholars at home and abroad always focus on the low-carbon urban development. This paper described the basic
theory of low-carbon city, analyzed the main factors effect the urban carbon emissions based on principal components
analysis method, and established evaluation model to adapt to the development of low-carbon city. Finally, reasonable
proposals have been proposed to provide scientific and theoretical basis for government decision making.
The Application of Wood in Modern Interior Design
Authors: Lin Chang
Published: August 2015

Wood, which is well known as the most natural material, has been playing a very important role in the development
of human society. The design concepts of promoting greens environmental protection have influenced the current
society profoundly. As a culture carrier, the designing manner of using wood as the central element is very popular. The
author is trying to dissect the beauty and the connotation of wood from the angle of Philosophy through this article. Then
she will analyze the current use of wood in the modern interior design with examples. At last, the corresponding design
principles and decoration methods will be summed up to combine with the actual situation of modern interior design.
Optimization Study on Enterprise Production Plan Based on Genetic Algorithm
Authors: Haidong Liu , Lixia Peng , Qin Li
Published: August 2015

This article aims at solving the common issues on enterprise production plan, based on combining JIT production
idea and actual product characteristic, to establish an optimized production plan model, with advanced and delayed
production as the least ambition and with the availability of the enterprise equipment and order quantity as constraint conditions.
Meanwhile, GA is used to solving the optimization model, and is used in the practical cases, so that the production
plan of the minimum cost is attained. The model has a great guiding significance on the decrease in the enterprise
production cost, the development of the use ratio of equipment and the rapid production planning.
On the Building of Shooting Load and Efficiency Evaluation Model of Competitive Basketball
Authors: Liu Ping , Shou Zhong-qiu , Wang Liang
Published: August 2015

Based on the diminishing marginal principle of shooting efficiency decreases along with shooting load, this paper
combined the original basic indicators and used diagonal deviation principle, to build a more accurate shooting load
and efficiency evaluation model with single index distribution algorithm. By the algorithm, applied research of shooting
load and efficiency of all players in the CBA team is conducted. In this way, this paper provided theoretical value and significance
for the scientization of competitive sport in China.
Recent Advances in Solid-State Analysis of Pharmaceuticals
Authors: Bukhari Syed Nasir Abbas , Hwei Ng Shin , Jantan Ibrahim
Published: August 2015

Current analytical techniques for characterizing solid-state pharmaceuticals include powder x-ray diffraction, differential scanning calorimetry, thermogravimetric analysis, infrared spectroscopy, Raman spectroscopy, electron microscopy and nuclear magnetic resonance. Powder x-ray diffraction and differential scanning calorimetry are mainstream techniques but they lack spatial resolution. Scanning electron microscopy and micro-Raman spectroscopy provide good chemical and optical characterization but they are not capable of analysing very small nanoparticles. Transmission electron microscopy and nano-thermal analysis can provide explicit characterization of nanoparticles but they are invasive. Nuclear magnetic resonance offers good spatial resolution but its use is mainly limited by poor sensitivity and high costs. In view of the many challenges posed by existing methods, new and novel techniques are being continually researched and developed to cater to the growing number of solid formulations in the pipeline and in the market. Some of the recent advances attained in the solid-state analysis of pharmaceutical are summarized in this review article.
Evaluation of soft tissue changes around the lips after bracket debonding using three-dimensional stereophotogrammetry
Authors: Kim Young-Kyun , Lee Nam-Ki , Moon Sang-Woon , Jang Moon-Jung , Kim Hyun-Suk , Yun Pil-Young
Published: August 2015

Objective: 

To evaluate the changes in soft tissue around the lips after orthodontic bracket debonding using three-dimensional (3-D) stereophotogrammetry.

Materials and Methods: 

3-D facial images of 20 subjects (10 men and 10 women; mean age, 26.81 ± 7.23 years) were taken with a white light scanner before and after debonding the labial brackets. Two images acquired from each subject were superimposed, and 15 soft tissue landmarks around the lips were plotted and analyzed. Statistical analysis was performed using both paired and independent t-tests (P < .05).

Results: 

There were no significant changes in position of any landmark on the x (left-right)- or y (vertical)-axes after removal of the brackets. However, the landmarks in the oral commissures and lower lip (LLP, −0.55 mm; Li, −0.44 mm; Ch-L, −0.56 mm, all P < .05) on the z (anteroposterior)-axis showed statistically significant differences. There were no significant positional changes of most landmarks on the x-, y-, or z- axes after bracket removal among the various genders and lip thicknesses.

Conclusions: 

There was a slight retrusion in the oral commissure and lower lip areas after debonding, but no changes were found in the upper lip area. This study showed that 3-D stereophotogrammetry can be useful in evaluating facial soft tissue changes in orthodontic patients.
Genetic Evidence for a Causal Role of Obesity in Diabetic Kidney Disease
Authors: Todd Jennifer N. , Dahlström Emma H. , Salem Rany M. , Sandholm Niina , Forsblom Carol ,   the FinnDiane Study Group, McKnight Amy J. , Maxwell Alexander P. , Brennan Eoin , Sadlier Denise , Godson Catherine , Groop Per-Henrik , Hirschhorn Joel N. , Florez Jose C.
Published: August 2015

Obesity has been posited as an independent risk factor for diabetic kidney disease (DKD), but establishing causality from observational data is problematic. We aimed to test whether obesity is causally related to DKD using Mendelian randomization, which exploits the random assortment of genes during meiosis. In 6,049 subjects with type 1 diabetes, we used a weighted genetic risk score (GRS) comprised of 32 validated BMI loci as an instrument to test the relationship of BMI with macroalbuminuria, end-stage renal disease (ESRD), or DKD defined as presence of macroalbuminuria or ESRD. We compared these results with cross-sectional and longitudinal observational associations. Longitudinal analysis demonstrated a U-shaped relationship of BMI with development of macroalbuminuria, ESRD, or DKD over time. Cross-sectional observational analysis showed no association with overall DKD, higher odds of macroalbuminuria (for every 1 kg/m2 higher BMI, odds ratio [OR] 1.05, 95% CI 1.03–1.07, P < 0.001), and lower odds of ESRD (OR 0.95, 95% CI 0.93–0.97, P < 0.001). Mendelian randomization analysis showed a 1 kg/m2 higher BMI conferring an increased risk in macroalbuminuria (OR 1.28, 95% CI 1.11–1.45, P = 0.001), ESRD (OR 1.43, 95% CI 1.20–1.72, P < 0.001), and DKD (OR 1.33, 95% CI 1.17–1.51, P < 0.001). Our results provide genetic evidence for a causal link between obesity and DKD in type 1 diabetes. As obesity prevalence rises, this finding predicts an increase in DKD prevalence unless intervention should occur.
Adipocyte Metrnl Antagonizes Insulin Resistance Through PPARγ Signaling
Authors: Li Zhi-Yong , Song Jie , Zheng Si-Li , Fan Mao-Bing , Guan Yun-Feng , Qu Yi , Xu Jian , Wang Pei , Miao Chao-Yu
Published: August 2015

Adipokines play important roles in metabolic homeostasis and disease. We have recently identified a novel adipokine Metrnl, also known as Subfatin, for its high expression in subcutaneous fat. Here, we demonstrate a prodifferentiation action of Metrnl in white adipocytes. Adipocyte-specific knockout of Metrnl exacerbates insulin resistance induced by high-fat diet (HFD), whereas adipocyte-specific transgenic overexpression of Metrnl prevents insulin resistance induced by HFD or leptin deletion. Body weight and adipose content are not changed by adipocyte Metrnl. Consistently, no correlation is found between serum Metrnl level and BMI in humans. Metrnl promotes white adipocyte differentiation, expandability, and lipid metabolism and inhibits adipose inflammation to form functional fat, which contributes to its activity against insulin resistance. The insulin sensitization of Metrnl is blocked by PPARγ inhibitors or knockdown. However, Metrnl does not drive white adipose browning. Acute intravenous injection of recombinant Metrnl has no hypoglycemic effect, and 1-week intravenous administration of Metrnl is unable to rescue insulin resistance exacerbated by adipocyte Metrnl deficiency. Our results suggest adipocyte Metrnl controls insulin sensitivity at least via its local autocrine/paracrine action through the PPARγ pathway. Adipocyte Metrnl is an inherent insulin sensitizer and may become a therapeutic target for insulin resistance.
The Relation Between HbA1c and Cardiovascular Events in Patients With Type 2 Diabetes With and Without Vascular Disease
Authors: Kranenburg Guido , van der Graaf Yolanda , van der Leeuw Joep , Nathoe Hendrik M.W. , de Borst Gert Jan , Kappelle L. Jaap , Visseren Frank L.J. , Westerink Jan
Published: August 2015

OBJECTIVE

Poor glycemic control is related to vascular events in patients with type 2 diabetes, but the presence of vascular disease might influence this relation. We evaluated the relation between glycemic control (HbA1c level) and new cardiovascular events and mortality in patients with type 2 diabetes, with and without vascular disease.

RESEARCH DESIGN AND METHODS

In a cohort of 1,687 patients with type 2 diabetes enrolled in the Second Manifestations of Arterial Disease (SMART) study, the continuous relation between HbA1c and cardiovascular events (composite of myocardial infarction, stroke, and vascular mortality) and all-cause mortality was evaluated with Cox proportional hazard analyses stratified for the presence of vascular disease.

RESULTS

During a median follow-up time of 6.1 years (interquartile range 3.1–9.5 years), a new cardiovascular event developed in 293 patients and 340 patients died. In all patients, the hazard ratio (HR) of the relation between HbA1c level and cardiovascular events was 1.06 (95% CI 0.97–1.17). A 1 percentage point higher HbA1c level was related to a 27% higher risk of a cardiovascular event in patients with type 2 diabetes without vascular disease (HR 1.27 [95% CI 1.06–1.51]), but not in patients with vascular disease (HR 1.03 [95% CI 0.93–1.15], P for interaction = 0.195). A 1 percentage point higher HbA1c level was related to a 16% higher risk of death (HR 1.16 [95% CI 1.06–1.28]) in patients with vascular disease and a nonsignificant 13% higher risk of all-cause mortality (HR 1.13 [95% CI 0.97–1.31]) in patients without vascular disease.

CONCLUSIONS

In patients with type 2 diabetes, there is a modest, but not statistically significant, relation between HbA1c level and cardiovascular events, and, as there was no statistically significant interaction, this relation was not different for patients with or without clinical manifestation of vascular disease.
Use of an α-Glucosidase Inhibitor and the Risk of Colorectal Cancer in Patients With Diabetes: A Nationwide, Population-Based Cohort Study
Authors: Tseng Yao-Hsien , Tsan Yu-Tse , Chan Wei-Cheng , Sheu Wayne Huey-Herng , Chen Pau-Chung
Published: August 2015

OBJECTIVE

Acarbose, an α-glucosidase inhibitor, has been shown to have antineoplastic effects on colorectal cancer in biomarker studies. We assessed the association between acarbose use in patients with diabetes and incident colorectal cancer.

RESEARCH DESIGN AND METHODS

We conducted a nationwide, population-based study using a large cohort with diabetes in the Taiwan National Health Insurance Research Database. Patients with newly diagnosed diabetes (n = 1,343,484) were enrolled between 1998 and 2010. One control subject not using acarbose was randomly selected for each subject using acarbose after matching for age, sex, diabetes onset, and comorbidities. Cox proportional hazards regression with a competing risks analysis was used to calculate the hazard ratios (HRs) and 95% CIs for the association between acarbose use and incident colorectal cancer for each eligible case-control pair (n = 199,296).

RESULTS

There were 1,332 incident cases of colorectal cancer in the cohort with diabetes during the follow-up period of 1,487,136 person-years. The overall incidence rate was 89.6 cases per 100,000 person-years. Patients treated with acarbose had a 27% reduction in the risk of colorectal cancer compared with control subjects. The adjusted HRs were 0.73 (95% CI 0.63–0.83), 0.69 (0.59–0.82), and 0.46 (0.37–0.58) for patients using >0 to <90, 90 to 364, and ≥365 cumulative defined daily doses of acarbose, respectively, compared with subjects who did not use acarbose (P for trend < 0.001).

CONCLUSIONS

Acarbose use reduced the risk of incident colorectal cancer in patients with diabetes in a dose-dependent manner.