bluuebunny/crossref_metadata_2025 huggingface dataset:
Pengembangan Formulasi Pasta Antiinflamasi Piroksikam Berbasis Ampas Tahu dalam Pemanfaatan Limbah Tahu Di Purwokerto
Authors: Sari Nita Triana , Riayah Putri Dewi , Fasya Nabila , A Ainul Mardziyati , B Namira Fadhilah , Nuryanti Nuryanti
Published: August 2019

The soybean curd residue is the waste product of soybean. It has potential for being excipients in pharmaceutical preparations because of its high carbohydrate element. This study aims to evaluate the soybean curd residue as excipients of piroxicam antiinfl ammatory paste. The excipient of soybean curd residue is made by isolating it with 0.1% KOH, then being characterized by physical, chemical, and functional test after becoming starch. It was prepared in piroxicam antiinfl ammatory paste preparations with ratio of soybean curd residue starch and manihot strach are F1 (0:0.25), F2 (0.25:0), F3 (1.25:1.25), F4 (1.5:1), and F5 (1:1.5). The result of physical and freeze-thaw stability test were analyzed descriptively. The data of viscosity, stickiness, and spreading power test were analyzed using one-way ANOVA. Soybean curd residue starch’s physic is slightly coarse, cubic-shapes powder, uneven surface and nonporous, slightly hygroscopic, and brownish-white. It has distinctive odor and has no taste. Chemical test showed that it contained carbohydrate and had pH 4.9. Functional test showed on average 15% it has viscosity 1959 cps, fl ow time 6.7 seconds and still angle 39.2o. Results of physical and stability tests showed that F3 were the best piroxicam antiinfl ammatory paste formula.
Activity of Fennel Fruit Extract (Foeniculum Vulgare Mill.) on Uterine of Immature Wistar Female Rat
Authors: Agustini Kurnia , Wulandari Dwi Riani , Rahayu Lestari
Published: August 2019

Fennel fruit (Foeniculum vulgare Mill.) is one of traditional plant medicine known having effects as anti-infl ammatory, analgesic and antioxidant. It also has been reputed to increase milk secretion, promote menstruation, facilitate birth, alleviates the symptoms of the male climacteric andincrease libido. Fennel fruit contains mainly with essential oils, such as anethole. It also contains lignan and flavonoids that are predicted having an estrogen-like eff ect or as phytoestrogen. Phytoestrogen is weak agonists for estrogen and can elicit statistic signifi cantly increases in uterine wet weight, at definite dose, in the uterothrophic bioassay. It is known that estrogen has eff ect on woman’s sexual organ, such as proliferation of uterine, mammary and ovary. The aim of this research was to investigate the estrogenic eff ect of fennel fruit’s ethanolic extract in immature, 19 days old, Wistar female rats. These models represent the climacteric/menopause phase, where estrogen level is very low because in this age, estrogen not yet produced by ovary. The testing animals were divided into fi ve groups, namely normal group, estradiol control group and three level doses of fennel extract (30 mg/200 g BW; 60 mg/200 g BW and 120 mg/200 g BW). The result indicated that start on 60 mg/200 g BW, fennel extract signifi cantly (α=0.05) increased wet weight of uterine. Fennel extract also lengthen the uterine and increased proliferation of uterine, such as uterine diameters, endometrium diameters and uterine thickness on dose 60mg/200gBW and 120mg/200gBW. Analysis of vaginal smear showed vaginal lubrication eff ect, surprisingly start on 60mg/200BW could induce estrous cycle.
Pengaruh Suplementasi Vitamin A pada Pengobatan Pasien TB Paru terhadap Percepatan Konversi Dahak pada Fase Intensif Di Wilayah Kerja Puskesmas Kecamatan Medan Kota
Authors: Marpaung Alexander , Siagian Parluhutan , Sari Dina Keumala
Published: August 2019

Background: Indonesia is in the second rank for the most TB (Tuberculosis) cases in the world after India. It is estimated that there are 1 million cases per year in Indonesia.

Objective: The objective of the research was to find out the influence of Vitamin A supplementation in the medication of pulmonary TB on the acceleration of sputum conversion time at intensive phase in the Working Area of Puskesmas in Medan Kota Subdistrict.

Methods: This research applied clinical testing design with experimental approach and Experimental Quasi method. The samples were 30 newly diagnosed pulmonary TB patients consisting of15 patients in the treatment group and 15 patients in the control group. They were ³18 years old, regularly consumed category I OAT with BMI ³18.5. The statistical data were analyzed by Mann-Whitney statistical testing at reliability rate 95% (p<0.05).       

Result: The results of the research on the treatment group discovered that they were mostly 18-27 years old 40.0%, male 73.3%, mostly university students 26.7%, had BTA conversion in the second week 80.0%; and the sputum conversion time was 2.4 weeks in average. The results of the research on the control group demonstrated that they were mostly 18-27 years old 33.3%, male 80.0%, mostly university students and entrepreneurs 20.0%, had BTA conversion in the second week 80%; and the sputum conversion time was 4.1 weeks in average. Vitamin A supplementation in the medication of pulmonary TB patients had some influence on the acceleration of sputum conversion at intensive phase (p= <0.001) < (alpha = 0.05).

Conclusion: Vitamin A supplementation in the medication of pulmonary TB patients had some influence on the acceleration of sputum conversion at intensive phase in the Working Area of Puskesmas in Medan Kota Subdistrict
Effect of extract and Salung Leaf Fraction (Psychotria viridiflora Reinv. Ex. Blume) As Sitotoksit, Antiproliferation and Applose of Apoptosis on Cancer Cell of Serviks HeLa
Authors: Salni Salni , Ismaryani Arlina , Setiawan Arum , Triwani Triwani
Published: August 2019

Cervical cancer ranks second of cancer that affects women in the world and the first order for women in developing countries. Plant Salung (Psychotria viridiflora Reinw. Ex. Blume) have been used for generations to treat various diseases. The purpose of the study to determine the effects of leaf extracts and fractions salung as the anti-proliferation and inducer of apoptosis in HeLa cervical cancer cells. Concentration of extracts and fractions of 640; 320; 160; 80; 40 µg/mL, while cisplatin using a concentration of 200; 100; 50; 25 µg/mL. The results showed IC50 extract value 380.7 µg/mL. n-hexane fraction amounted to 229.3 µg/mL. ethyl acetate fraction of 116.8 µg/mL, and amounted to 562.8 µg/mL fraksi methanol water, so that the ethyl acetate fraction had enough categories active cytotoxic activity seen from the IC50. To further test the researchers only tested the active fraction is the fraction of ethyl acetate. Results ethyl acetate fraction doubling time is 58, which means replicating or proliferating cells on hour to 58 while the cells replicate cisplatin on the hour to 64.5 and the control cell on the hour to 41. Results of flowcytometry showed ethyl acetate fraction induce apoptosis by 72.82% while cisplatin 87.96%. It can be concluded that the extracts and fractions of leaves salung have a cytotoxic effect, acts as an anti-proliferation and inducer of apoptosis in HeLa cervical cancer cell.
FAKTOR PENDORONG DAN PENARIK WISATAWAN TERHADAP JAZZ GUNUNG BROMO SEBAGAI ATRAKSI MUSIC TOURISM DI JAWA TIMUR
Authors: Azhar Melati Putri Dhea , Nurhidayati Hindun
Published: August 2019

Tujuan dari penelitian music tourism ini adalah untuk mengidentifikasi kondisi eksisting Jazz Gunung serta mengidentifikasi faktor pendorong dan penarik wisatawan terkait Jazz Gunung Bromo sebagai atraksi music tourism di Jawa Timur. Metode penelitian yang digunakan dalam penelitian ini adalah deskriptif kualitatif, dengan memanfaatkan data primer dan sekunder. Metode pengumpulan data yang digunakan adalah observasi, wawancara, penyebaran kuesioner, serta dokumentasi. Hasil penelitian ini menunjukkan bahwa kondisi eksisting Jazz Gunung Bromo sudah memenuhi indikator atraksi dari Walsh-Heron dan Stevens dalam Swarbrooke. Faktor pendorong yang paling dominan dalam mendorong wisatawan untuk menghadiri event Jazz Gunung Bromo adalah motivasi fisik, dan faktor penarik wisatawan yang membuat wisatawan tertarik untuk menghadiri Jazz Gunung Bromo adalah tempat serta pengisi acara.
Authors: Pereira Rogério Amaral
Published: August 2019

Este artigo apresenta como referência o diálogo acadêmico entre os termos: mito, linguagem e religião, que em conjunto transpõe da cultura do homem, mediante ao contexto de símbolos e signos que são constituídos nos diversos instantes da vida humana e contemplados no conjunto da religiosidade, neste caso específico de estudo, o da Umbanda. Assim, a abordagem acadêmica, busca contribuir para a Geografia, em especial, nos estudos voltados à Geografia da Religião. E através, do ponto filosófico norteador de Ernst Cassirer (1874-1945) e suas formas simbólicas: a da linguagem e a do pensamento mítico, o ensaio tem por objetivo apresentar um estudo entre a forma do campo religioso e dos símbolos interpretados por Pierre Bourdieu (1930-2002) e a interpretação do discurso por Paul Ricoeur (1913-2005), pois a religião ao ser atribuída como um texto é possível uma hermenêutica. Deste modo, o artigo apresenta-se dividido em duas etapas de reflexão: na primeira o diálogo com grande enfoque filosófico entre mito, linguagem e religião; e na segunda etapa uma interpretação geográfica da relação do sagrado com o espaço. Entremeado a tudo isso, foi possível exibir reflexões para o estudo geográfico vinculado as espacialidades do sagrado.
Authors: Aguilar Javier Enrique
Published: August 2019

A marcha pelos direitos das pessoas com diversidade sexual é celebrada em várias cidades do mundo e da Colômbia não é uma exceção, pois realizou uma análise da marcha proposto na cidade de Bogotá a partir de etnografia em três cenários diferentes, como observador da viagem (2009), como um participante na marcha (2010) e, como parte da organização deste (2011), com a única finalidade de interpretar a construção eo reconhecimento dessas identidades dentro da cidade e como você está ratificada no palco do público, rua, carnaval de rua em que a sociedade integra diferentes identidades sexuais envolvendo, ação e visibilidade da resistência cultural produzida pelo movimento LGBTI com iniciativas individuais e de grupo transgridem espaços heteronormativas.
Use Of Code Mixing Between Indonesian And English In Indonesian Advertisement Of Gadis
Authors: Marzona Yessy
Published: August 2019

This tendency is noticed when people use many ways of language variations to communicate or express their thought, ideas, and feelings. One example of these variations is code mixing. Code mixing is insertion of a piece of word other than that of your language, and you have no specific purpose or intention when doing communication. Code mixing is different from borrowing. Code mixing usually happens while people communicate in oral or written and in informal situation. In the case of code mixing, people sometimes mix two languages, particularly between national and a foreign language like English. However, code mixing does not only exist between the languages, there is also the mixing between national and regional languages. The researcher use GADIS to do this research. It was found that there were three forms of code mixing used in advertisement in GADIS. They were words, phrases and sentences which were put in the middle of the sentence of advertisements. Meanwhile, the use of code mixing in advertisements had many functions based on the purposes of communication, as we knew; advertisement was an advertiser’s way to communicate to the consumer, reader in this case. So, in this research it was found that there were three functions of the use of code mixing. They were greeting, informing, and rejecting.
knight’s Life Between Love and Duty As Seen in Sir Walter Scott’s Ivanhoe
Authors: Liswandi Melki
Published: August 2019

The problem in this thesis is the life of a knight who has to choose between duty and love. Dif analysis on the main task because on one side must perform his duties as a knight, and on the other side must follow his conscience to get his love. The problem of duty and love does not fit in the story. The purpose of this study is to evaluate the duties and responsibilities of the knight in performing his duty to the country where the knight is also confronted with his feelings and love, be a confrontation between the duty and responsibility to the knight. In this writing, literature research is taken as a method of data. As for the method of data analysis, the authors perform comparative procedures with the understanding of novels, figures, and also psychiatric theory. Technical techniques data data research results relevant to the research. In data analysis techniques, the author uses the technique of genetic structuralism by analyzing the knight in the Ivanhoe novel through psychic theory, the writer must see the confrontation that the knight must enter in choosing a task or love. The findings in this thesis are: 1) the knight prefers the task to fullness and prefers love in the end, 2) at the beginning of the story, the knight prefers to give priority to his duty to the king so that he is carried away Rowena, his beloved girl 3) At the end of the story, the knight returns to give priority to his love for Rowena.
Molecular Gas toward the Gemini OB1 Molecular Cloud Complex. III. Chemical Abundance
Authors: Wang Chen , Yang Ji , Su Yang , Du Fujun , Ma Yuehui , Zhang Shaobo
Published: August 2019

We present analyses of the 13CO abundance

and the abundance ratio

of molecular clouds by collecting 12CO, 13CO, and C18O (1–0) transitions toward the Galactic anti-center in the ranges

and

. The

area contains eight clouds, which can be divided into two types according to

. Type I clouds, including the chain of Lynds dark clouds, West Front, Gemini OB1 giant molecular cloud (GGMC) 1, and Horn, have lower

(mean value <10) and lower column density with relatively lower temperature. Type II clouds, including GGMC 2, GGMC 3, GGMC 4, and Swallow, have a higher abundance ratio

(mean value >10) and higher column density with relatively higher temperature. For all clouds,

increases from

at the edge to

in the interior, which is probably due to an opacity effect of 12CO. In GGMC 2–4, the mean

of the molecular gas associated with H ii regions and IRAS sources is ∼14, slightly larger than that (∼9) of other subregions. This can be explained by selective far-UV photodissociation of C18O. By comparing our sample with other clouds in the plot of

against 13CO column density, we find that type I clouds are probably at an earlier evolutionary stage than type II clouds.
Stellar Metallicities and Elemental Abundance Ratios of z ∼ 1.4 Massive Quiescent Galaxies*
Authors: Kriek Mariska , Price Sedona H. , Conroy Charlie , Suess Katherine A. , Mowla Lamiya , Pasha Imad , Bezanson Rachel , Dokkum Pieter van , Barro Guillermo
Published: August 2019

The chemical composition of galaxies has been measured out to z ∼ 4. However, nearly all studies beyond z ∼ 0.7 are based on strong-line emission from H ii regions within star-forming galaxies. Measuring the chemical composition of distant quiescent galaxies is extremely challenging, as the required stellar absorption features are faint and shifted to near-infrared wavelengths. Here, we present ultradeep rest-frame optical spectra of five massive quiescent galaxies at z ∼ 1.4, all of which show numerous stellar absorption lines. We derive the abundance ratios [Mg/Fe] and [Fe/H] for three out of five galaxies; the remaining two galaxies have too young luminosity-weighted ages to yield robust measurements. Similar to lower-redshift findings, [Mg/Fe] appears positively correlated with stellar mass, while [Fe/H] is approximately constant with mass. These results may imply that the stellar mass–metallicity relation was already in place at z ∼ 1.4. While the [Mg/Fe]−mass relation at z ∼ 1.4 is consistent with the z < 0.7 relation, [Fe/H] at z ∼ 1.4 is ∼0.2 dex lower than at z < 0.7. With a [Mg/Fe] of

the most massive galaxy may be more α-enhanced than similar-mass galaxies at lower redshift, but the offset is less significant than the [Mg/Fe] of 0.6 previously found for a massive galaxy at z = 2.1. Nonetheless, these results combined may suggest that [Mg/Fe] in the most massive galaxies decreases over time, possibly by accreting low-mass, less α-enhanced galaxies. A larger galaxy sample is needed to confirm this scenario. Finally, the abundance ratios indicate short star formation timescales of 0.2–1.0 Gyr.
Large Bowel Occlusion: Clinical and Imaging Characteristics - Caecum Volvulus
Authors: Coco Danilo , Leanza Silvana
Published: August 2019

BACKGROUND: Caecum volvulus (CV) is defined as an axial twisting that causes an inversion position of the caecum, ascending colon and terminal ileum. This anatomical finding is responsible for some clinical features. Obstruction and strangulation are the most important and life-threatening.
CASE PRESENTATION: We are presenting a 50 years old woman presented to the hospital with sudden acute severe abdominal pain and distension of about 24 hours associated with vomiting and no flatus.
CONCLUSION: Mortality in patients with CV can be kept near 10%-12% if operative intervention is accomplished before caecum strangulation. Once the cecum has become gangrenous, a death rate of 30 to 40% can be expected. Tailored made surgery on patients status is the strategy.
Common Practice of Hypospadias Management by Pediatric Urologists in Indonesia: A Multi-center Descriptive Study from Referral Hospitals
Authors: Duarsa Gede Wirya Kusuma , Tirtayasa Pande Made Wisnu , Daryanto Besut , Nurhadi Pradana , Renaldo Johan , Tarmono Tarmono , Utomo Trisulo , Yuri Prahara , Siregar Safendra , Wahyudi Irfan , Situmorang Gerhard Reinaldi , Palinrungi Muhammad Asykar A. , Hutasoit Yonas Immanuel , Hutahaean Andre Yudha Alfanius , Zulfiqar Yevri , Sigumonrong Yacobda H. , Mirza Hendy , Rodjani Arry
Published: August 2019

BACKGROUND: Hypospadias is the second most common congenital anomalies among human congenital disabilities. There are over 300 surgery techniques being introduced to treat hypospadias. The successful of hypospadias repair is assessed by several outcomes as well as complications following surgery.
AIM: This study aims to show the multicenter hypospadias data in Indonesia descriptively.
METHODS: All the data were compiled based on questionnaires, which were distributed to Indonesian pediatric urologists. The questionnaire includes several questions containing demographic aspect, preferred techniques being used, and complications being found regarding hypospadias repair.
RESULTS: Eighteen Indonesian pediatric urologists from 12 centres involved in this study. The data were collected from June – September 2018 based on the surgeon’s experience throughout 2017. From 591 cases based on the returned questionnaire, penile-type hypospadias was the most common type of hypospadias being treated (35.7%) followed by penoscrotal (28.9%) and scrotal-type (12.9%). Moderate severity of chordee was mostly seen among all cases (40.6%). Tubularised incised plate (TIP), + Thiersch Duplay, was the most common technique being used to treat hypospadias (44.3%), followed by onlay island preputial flap (14.9%) and two-stage technique (14%). The incidence of urethrocutaneous fistulae in this study was 13.9%.
CONCLUSION: This study showed how Indonesian pediatric urologists dealt with hypospadias cases. TIP + Thiersch Duplay procedure being the preferred technique used by most participants and the rate of urethrocutaneous fistulae as one of the complications was comparable with previous studies.
Asthma and Chronic Obstructive Pulmonary Disease Associated With Occupational Exposure in Dairy Farmers - Importance of Job Exposure Matrices
Authors: Stoleski Saso , Minov Jordan , Karadzinska-Bislimovska Jovanka , Mijakoski Dragan , Atanasovska Aneta , Bislimovska Dragana
Published: August 2019

AIM: To evaluate the prevalence of chronic respiratory symptoms, lung function impairment, and chronic obstructive respiratory diseases in dairy farmers. Our objective is to then examine their relation to exposure duration and to explore the usefulness of job exposure matrices as tools for exposure assessment, and predictors for respiratory health impairment.
METHODS: A cross-sectional study was performed, including 83 dairy farmers (mean age: 52.6 ± 8.7 years; mean exposure duration: 23.7 ± 7.6 years) and 80 office workers as a control group (mean age: 52.7 ± 8.2 years) matched for age, smoking habits, and socioeconomic status. Methods of evaluating examined subjects included a questionnaire on respiratory symptoms in the last 12 months, spirometry and histamine challenge, as well as the use of job exposure matrices (JEM).
RESULTS: Dairy farmers had a significantly higher prevalence of cough (38.5), phlegm (27.7%), and wheezing (21.7%), than controls (p < 0.05). All mean baseline spirometric parameters were lower in dairy farmers compared to the controls, but statistical significance was confirmed only for MEF25, MEF50, and MEF75% (p = 0.010, p = 0.001, and p = 0.004, respectively). The prevalence of bronchial hyperresponsiveness, asthma, and chronic obstructive pulmonary disease was higher in dairy farmers but without statistical significance. JEM were useful tools for exposure assessment and predictors of factors for asthma and COPD development.
CONCLUSION: The results suggest that occupational exposure among crop farmers is associated with a higher prevalence of respiratory symptoms, lung function impairment, and a higher prevalence of chronic respiratory diseases. JEM showed good potential for farming exposure evaluation and promoted their applicability within the diagnostic algorithm focused on respiratory health assessment.
Neotypification of Protoparmeliopsis garovaglii and molecular evidence of its occurrence in Poland and South America
Authors: Szczepańska Katarzyna , Rodriguez-Flakus Pamela , Urbaniak Jacek , Śliwa Lucyna
Published: August 2019

Protoparmeliopsisgarovagliiis a widely distributed placodioid lichen, which develops a distinctly rosette thallus, composed of elongated and strongly inflated to sinuous-plicate lobes. The taxon is characterised by high morphological plasticity and varied composition of secondary metabolites. However, the epithet was never typified. As such, the identity ofP.garovaglii, in its strict sense, was unknown for a long time. Our phylogenetic ITS rDNA analyses, including newly generated sequences, show that European (Austria, Poland), North American (USA) and South American (Bolivia, Peru) specimens ofP.garovagliiare placed in a strongly supported monophyletic clade, sister toP.muralis. We provide the first molecular evidence of the occurrence ofP.garovagliiin South America (Bolivia and Peru) and the second record in Central Europe (Poland) was also provided. Furthermore, we neotypifyP.garovagliiand it is reported here for the first time from Poland.
Real-world Longterm Effectiveness of Tumor Necrosis Factor Inhibitors in Psoriatic Arthritis Patients from the Rheumatic Diseases Portuguese Register
Authors: Vieira-Sousa Elsa , Eusébio Mónica , Ávila-Ribeiro Pedro , Khmelinskii Nikita , Cruz-Machado Rita , Rocha Teresa Martins , Bernardes Miguel , Santos-Faria Daniela , Silva Joana Leite , Santos Helena , Miguel Cláudia , Carvalho Pedro , Costa Tiago , Duarte Ana Catarina , Meirinhos Tiago , Nero Patrícia , Fonseca João Eurico , Santos Maria José
Published: August 2019

Objective.

To assess longterm effectiveness of tumor necrosis factor inhibitors (TNFi) in patients with psoriatic arthritis (PsA) registered in the Rheumatic Diseases Portuguese Register, exposed to at least 1 TNFi, prospectively followed between 2001 and 2017.

Methods.

Kaplan-Meier analysis was performed for first-, second-, and third-line TNFi. Responses included European League Against Rheumatism (EULAR) criteria, Disease Activity Index for Psoriatic Arthritis (DAPSA), minimal disease activity (MDA), and Ankylosing Spondylitis Disease Activity Score (ASDAS) at 3 and 6 months. Baseline predictors of discontinuation and response were studied using Cox and multivariable multinomial/logistic regression models.

Results.

The 750 patients with PsA showed drug retention of 4.1 ± 3.4 years (followup 5.8 ± 3.8 yrs) for first TNFi. Switching to a second (189 patients) or third (50 patients) TNFi further decreased survival by 1.1 years. Female sex, higher baseline 28-joint count Disease Activity Score, and infliximab were predictors of first TNFi discontinuation. After 6 months of the first TNFi, 48.7% of patients achieved a good EULAR criteria response and 20.9% were in DAPSA remission. There were 11.4% in MDA, and 56.4% had a good ASDAS. Responses to the second TNFi were significantly inferior compared to responses to the first TNFi. Female sex and higher baseline Health Assessment Questionnaire–Disability Index were negatively associated with good EULAR response at 3 months, and obesity decreased the chance of response at 6 months.

Conclusion.

In this study, switching to a second or third TNFi was associated with significantly lower drug survival and response rates for patients with axial and peripheral PsA subtypes. More successful therapeutic approaches will require considering the effect of sex and obesity on TNFi effectiveness.
Reliability and Validity of Patient-reported Outcomes Measurement Information System Short Forms in Ankylosing Spondylitis
Authors: Hwang Mark C. , Ogdie Alexis , Puravath Abin , Reveille John D.
Published: August 2019

Objective.

To assess the reliability and validity in ankylosing spondylitis (AS) of selected Patient Reported Outcomes Measurement Information System (PROMIS) Short Forms (SF) developed by the US National Institutes of Health. The analysis was done across core sets and patient-identified domains of the Assessment of Spondyloarthritis international Society.

Methods.

Participants in the Prospective Study of Outcomes in Ankylosing Spondylitis (PSOAS), an ongoing, prospective longitudinal observational study, completed 6 PROMIS SF assessing global health, depression, fatigue, physical function, pain intensity, and pain interference during their PSOAS visits from September 2017 to January 2019. Test-retest reliability and internal consistency were assessed using intraclass correlation coefficients and Cronbach’s alpha coefficient, respectively. PROMIS SF were compared to legacy measures collected. Construct validity was evaluated through examination of score distributions and floor effects, and through examination of the Spearman correlation coefficients between PROMIS measures and existing legacy AS measures. Discriminant validity was tested across Ankylosing Spondylitis Disease Activity Score (ASDAS) groups.

Results.

Participants (n = 119) were mostly male (69%), white (81%), and with a mean (SD) age of 51 (± 15) years. Legacy measures demonstrated floor effects that were not present in PROMIS SF. Good test-retest reliability (r > 0.8) and excellent internal consistency (α > 0.9) was noted in the PROMIS SF. The 6 PROMIS SF correlated moderately to strongly [ρ 0.68 (Depression) to −0.87 (Physical Function)] with appropriate legacy measures. PROMIS scores measures worsened significantly (p < 0.05) with higher ASDAS groups.

Conclusion.

This study supports the reliability and construct validity of PROMIS SF to assess AS symptoms from a single-center sample of patients with AS. Further research is needed to test responsiveness, feasibility/resource burden, and different cultural/societal contexts for patients with AS.
Association of Pharmacological Biomarkers with Treatment Response and Longterm Disability in Patients with Psoriatic Arthritis: Results from OUTPASS
Authors: Jani Meghna , Chinoy Hector , Barton Anne
Published: August 2019

Objective.

To identify (1) whether tumor necrosis factor inhibitor (TNFi) drug levels/anti-drug antibodies (ADAb) are associated with treatment response and disability in patients with psoriatic arthritis (PsA); and (2) the factors associated with TNFi drug levels.

Methods.

Patients were recruited from a national multicenter prospective cohort with longitudinal serum samples and 28-joint count Disease Activity Scores (DAS28)/Health Assessment Questionnaire (HAQ) measurement over 12 months.

Results.

Adalimumab (ADA) drug levels were significantly associated with ΔDAS28 (β 0.055, 95% CI 0.011–0.099; p = 0.014) and inversely with HAQ over 12 months (β −0.022, 95% CI −0.043 to −0.00063). Factors significantly associated with ADA drug levels were ADAb levels and body mass index.

Conclusion.

Drug level testing in ADA-initiated PsA patients may be useful in determining treatment response/disability over 12 months.
Increased Cardiovascular Risk and All-cause Death in Patients with Behçet Disease: A Korean Nationwide Population-based Dynamic Cohort Study
Authors: Ahn Hyo-Suk , Lee Dongjae , Lee Soo Young , Kim Yeong Ho , Lee Ji Hyun , Yu Dong Soo , Han Kyung-Do , Park Yong Gyu , Lee Young Bok
Published: August 2019

Objective.

Behçet disease (BD) is a chronic inflammatory multiorgan disease. An increased risk of cardiovascular disease (CVD) and heightened death rate with BD have been suggested, but to our knowledge, a nationwide large-scale study has not been conducted to date. This study aimed to determine the overall CV risk and death rate in patients with BD versus controls using the Korean National Health Insurance Service claim database.

Methods.

Patients with BD (n = 5576) with no previous history of CVD were selected from 2010 to 2014. An age- and sex-matched control population of individuals without BD (n = 27,880) was randomly sampled at a ratio of 5:1. Both cohorts were followed for incident CVD or all-cause death until 2015.

Results.

The risks of myocardial infarction (HR 1.72, 95% CI 1.01–2.73) and stroke (HR 1.65, 95% CI 1.09–2.50) were significantly higher in patients with BD than in controls. Patients with BD also had a significantly higher risk of all-cause death (HR 1.82, 95% CI 1.40–2.37) compared to controls.

Conclusion.

Korean patients with BD had a higher overall risk of CVD than did those without BD. Therefore, patients with BD must be carefully monitored for the potential development of CVD to ensure that appropriate early treatments are delivered.
Nathalie, une jouissance insupportable
Authors: Chanot Cécile , Guérin Valérie , Portier Gérard
Published: August 2019

Certains sujets sont en proie à de tels mouvements de la jouissance qu’il est parfois difficile, en tant que clinicien, de garder les pieds sur terre et toute sa raison. La course en avant pulsionnelle ne trouve alors parfois, comme butée, que le passage à l’acte, le rejet, la loi ou la protection. Les cliniciens aux prises, dans leur clinique, avec de tels affects ont l’obligation d’inventer des modalités de vidage et d’éclairage. Ici, la situation de Nathalie sera prétexte pour présenter une pratique en sessad qui propose un traitement de la jouissance prenant en compte la dimension inconsciente, tant du côté du patient que de celui du clinicien, par la modalité du travail en binôme, éducatrice-psychologue au quotidien.
Le SAS2A, une ruée vers l’air ?
Authors: Houdin Fanny , Vallias Coralie , Rossignol Hervé , Lucas Pascal , Derabours Nelly
Published: August 2019

Cet écrit s’inscrit dans le désir du sas2a de rendre compte des douze ans d’existence d’un service « expérimental », faisant coexister dans une même équipe travailleurs sociaux et soignants psychiatriques. Le service propose des hébergements et un travail d’accompagnement à des personnes suivies par le pôle Paris Centre. Ce texte tend à présenter le fonctionnement de cette équipe singulière qui permet aux personnes de se rétablir et d’habiter. Un témoignage d’une personne accompagnée vient confirmer la pertinence de ce service.
A (Des)motivação nas aulas de Educação Física e a satisfação das necessidades de competência, autonomia e vínculos sociais
Authors: Aniszewski Ellen , Henrique José , Oliveira Aldair José de , Alvernaz Aline , Vianna José Antônio
Published: August 2019

O desinteresse nas aulas de educação física tem sido percebido nos anos finais do ensino fundamental. Os estudos sobre motivação na disciplina na última década reportam estreita relação entre a satisfação das necessidades psicológicas básicas e a participação nas aulas. A pesquisa investigou os aspectos motivacionais que conduzem ao afastamento dos alunos nas aulas de educação física, no nono ano do ensino fundamental. A pesquisa adotou o método misto sequencial. A análise quantitativa foi de natureza descritiva e a qualitativa de natureza interpretativa. A amostra na fase extensiva foi composta de 85 alunos de nono ano da rede Municipal do Rio de Janeiro, dentre os quais foram selecionados seis alunos para a fase intensiva. Para a recolha de dados na fase quantitativa, recorreu-se ao Questionário de Necessidades Psicológicas Básicas, adaptado para a língua portuguesa; e na qualitativa uma entrevista, realizada sob a técnica do Círculo Hermenêutico Dialético. Os resultados indicam que a falta de habilidade (competência), falta de diversificação dos conteúdos (competência/autonomia) e a falta de oportunidades de participação na tomada de decisão no desenvolvimento da disciplina (autonomia) estão entre os principais motivos que levam os alunos ao desinteresse pelas aulas de educação física no final do ensino fundamental.
Existe influência do nível de atividade física habitual na capacidade aeróbia e variabilidade da frequência cardíaca em mulheres na fase da pós menopausa?
Authors: Dias Wellington Gonçalves , Batista Danilo Rodrigues , Meneghel Vlademir , Ornelas Felipe De , Silva Jannes S Camargo , Braz Tiago Volpi
Published: August 2019

O objetivo da pesquisa foi verificar se o nível de atividade física habitual (NAFH) de mulheres em fase pós menopausa apresenta influência na capacidade aeróbia e ativação parassimpática do coração em repouso. Participaram do estudo 30 mulheres na fase da pós menopausa (59,3 ± 5,3 anos; 1,58 ± 0,06 m;  64,5 ± 9,6 kg; 25,6 ± 3,1; %G = 27 ± 5%). Foram divididas em 2 grupos a partir da mediana do número de passos no pedômetro do NAFH (G1 = NAFH). Foi realizado um teste incremental de caminhada progressiva (ISWT) e análise da variabilidade da frequência cardíaca (VFC) em repouso na posição supinada. Foram encontradas diferenças substanciais entre os grupos G1 e G2 para número de passos (p = 0,0001; TE = 2,55 [grande], IC 90% [0,96]; quase certeza a diferença [100/0/0%]), distância percorrida no ISWT (p = 0,0002; TE = 2,24 [grande], IC 90% [0,84]; quase certeza a diferença [100/0/0%]) e índice de ativação parassimpática da VFC (p = 0,0001; TE = 1,56 [moderado], IC 90% [0,62]; quase certeza a diferença [100/0/0%]). Conclui-se que mulheres na fase da pós menopausa com maior NAFH possuem maior capacidade aeróbia e modulação parassimpática da VFC.
Durability of Coatings Based on Sol Silicate Paint
Authors: Loganina Valentina , Mazhitov Yerkebulan B. , Skachkov Yuri Petrovich
Published: August 2019

The results of the study provide information on the resistance of coatings based on the solof silicate paint in the process of freezing and thawing. It was found, that coatings based on sol silicatepaints are characterized by a higher resistance compared of silicate coatings. It is shown, that thecoatings withstood 50 cycles of alternate freezing and thawing. The surface energy of the coatingswas calculated using the critical surface tension of the fluid at the interface with the solid. Thedispersion contribution in the intermolecular interaction between the particles of the coatings wasestimated. The values of the surface tension of the coatings and the values of the dispersioncomponent of the surface energy of the coatings — the complex Hamaker constant — are calculated.It was revealed, that after testing a decrease in the values of the Hamaker constant is observed. It wasestablished, that after testing for frost resistance, the values of the Hamaker constant for coatingsbased on sol of silicate paint are higher compared to coatings based on silicate paint.
Drying Shrinkage Performance of Ambient Cured Blended Alkali-Activated Concrete
Authors: Yousuf Fatima , Junaid M. Talha , Al-Toubat Salah
Published: August 2019

The environmental burden due to the production and use of Ordinary Portland Cement(OPC) has become significant in terms of resource use and atmospheric emissions. Alkali-activatedbinders have gained significant attention in recent years as a possible alternative to OPC. Concreteundergoes physical and chemical changes through its lifetime. These changes affect propertiesresulting in either increase or decrease of performance and serviceability. Concrete contracts due tothese changes leading to shrinkage. Shrinkage induces tensile stresses within the members, whichleads to a tendency of cracking, resulting in compromised durability. Shrinkage behavior analysis ofAlkali-Activated Concrete (AAC), without any external loading, is crucial to assess as there is limiteddata available. To further test for shrinkage under restraint conditions, mix development of AAC isnecessary. Mechanical properties and drying shrinkage potential of AAC are evaluated and comparedwith OPC concrete. Basic properties assessed to understand the performance of AAC are compressivestrength, splitting tensile strength and free drying shrinkage. Drying shrinkage test is performed as perASTM C157 for 90 days. Furthermore, the effect of different curing regimes (dry curing, three daysmoist curing, and seven days moist curing) on the mechanical properties and shrinkage is evaluated.The results show that drying shrinkage of AAC exhibit similar behavior to that of OPC concrete whilehaving better early-age strength under moist curing regimes.
Preparation of Ag/SnO2 Contact Material by Chemical Deposition
Authors: Wang Jun Bo , Qiu Hong Hua , Si Fang , Liu Song Tao , Matsumoto Norihisa
Published: August 2019

In order to improve the dispersion of SnO2 in Ag matrix, Ag/SnO2 contact materials wasprepared by optimized chemical deposition process. The micro-morphology and phase of theAg/SnO2 contact materials were tested by metallographic microscope and XRD. The results showedthat the combination of mechanical stirring and ultrasonic stirring can effectively improve thedispersion of SnO2 in Ag matrix, the Vickers hardness, conductivity and density of the Ag/SnO2contact materials with 88% Ag content are 114.4HV, 77.4% IACS and 9.75g/cm3 respectively. Theseprovide data reference for preparation of Ag/SnO2 contact materials with uniform SnO2 distributionin Ag matrix.
Effective Strategies for Teaching Teamwork
Authors: Dirks Joni L.
Published: August 2019

Teamwork is essential for health care providers, who must work together to ensure safe and effective patient care. The ability to function effectively as a team is especially important in critical care, where ad hoc teams are brought together for short-term management of crisis situations. Teamwork training has been widely implemented, but ongoing education and practice are needed to maintain and improve competency. This article reviews some of the literature on team science and provides recommendations for enhancing training to promote development of a shared mental model. Strategies such as ensuring multidisciplinary participation, clarifying team resources and goals, and creating practice scenarios can increase the effectiveness of training for critical care teams. Evaluation can provide immediate feedback on learning outcomes and may facilitate subsequent transfer of learning to the clinical setting. Interventions that improve a team’s ability to work toward a common goal can improve outcomes for critically ill patients.
Antioxidant potentials of Miyan Kuka (Baobab leaves)
Authors: Otong Eduitem S. , Musa Sunday A.
Published: August 2019

Antioxidant is any substance that directly scavenges reactive oxygen species (ROS) or indirectly acts to up-regulate antioxidant defenses or inhibit ROS production. The review is aimed at highlighting the components of baobab leaves with antioxidant capabilities. Articles were searched from the Directory of Open Access Journals, PubMed, Google Scholar, Science Direct using key words such as composition of baobab leaves, antioxidant properties of baobab leaf, reactive oxygen species, oxidative stress and antioxidant. The result showed that boabab leaves are good sources of food with a lot of antioxidant components such as vitamin C, carotenes, flavonoids, zinc etc. These antioxidant components help to regulate ROS including free radicals such as superoxide anion, hydroxyl radical, as well as non-radical molecules like hydrogen peroxide, singlet oxygen. Baobab leaves carry out the antioxidant activities through the following processes: scavenging and neutralizing free radicals, singlet oxygen quenching, superoxide radical scavenging, hydrogen donation, metal chelating, enzymes inhibition, peroxide decomposing and synergies. They also help in activating antioxidant enzymes, reduce α-tocopherol radicals, reduce nitrosative stress, prevent oxidases, and increase levels of uric acid and low molecular weight molecules which ultimately help to reduce oxidation in the long run. Baobab leaves are rich in phytochemicals with a lot of antioxidant capabilities due to the present of several components like vitamin C, carotenes, flavenoids, etc. These components work in different ways to regulate reactive oxygen species and by extension prevent oxidative stress.
Trajectories of alliance ruptures in the psychotherapy of adolescents with borderline personality pathology: timing, typology and significance
Authors: Schenk Nathalie , Zimmermann Ronan , Fürer Lukas , Krause Mariane , Weise Sindy , Kaess Michael , Schlüter-Müller Susanne , Schmeck Klaus
Published: August 2019

Jeremy Safran and his research group suggest that rupture-repair processes are important for the therapeutic change in patients with personality disorders. In this exploratory study, we describe alliance ruptures and resolutions on a session-by-session basis in a clinical sample of adolescents with Borderline Personality Pathology (BPP). Three research questions are addressed: i) Is there a typical trajectory of alliance ruptures over treatment time? ii) Which rupture and resolution markers occur frequently? iii) Which rupture markers are most significant for the therapeutic alliance? Ten patients who presented with identity diffusion and at least three Borderline Personality Disorder criteria were studied and treated with Adolescent Identity Treatment. Alliance ruptures and resolutions were coded in 187 therapy sessions according to the Rupture Resolution Rating System. Mixed-effect models were used for statistical analyses. Findings supported an inverted U-shaped trajectory of alliance ruptures across treatment time. The inspection of individual trajectories displayed that alliance ruptures emerge non-linearly with particular significant alliance ruptures appearing in phases or single peak sessions. Withdrawal rupture markers emerged more often compared to confrontation markers. However, confrontation markers inflicted a higher impact or strain on the immediate collaboration between patient and therapist compared to withdrawal markers. Clinicians should expect alliance ruptures to occur frequently in the treatment of adolescents with BPP. The findings support the theory of a dynamic therapeutic alliance characterised by a continuous negotiation between patients and therapists.
Why did she leave? Development of working alliance in a case of psychotherapy for depression
Authors: Doležal Petr , Čevelíček Michal , Řiháček Tomáš , Roubal Jan , Hytych Roman , Ukropová Lucia
Published: August 2019

The present case study aims to explore the unfolding of the working alliance in a case that ended with the client dropping out of psychotherapy, unilaterally cutting off her contact with the therapist. However, both quantitative and qualitative outcome assessments strongly suggested that. An analysis of session transcripts, the Client Change Interview, and the Interpersonal Process Recall interviews for three selected sessions was used to analyze the development of the working alliance and its contribution to the dropout. This case study illustrates how the working alliance is constructed differently during the different phases of the therapeutic process. Specifically, the fruitful problem-solving in the first part of psychotherapy helped the client to improve her functioning. Yet this intervention seemed to exhaust its potential over time, and later the dyad had trouble finding another useful mode of interaction due to the interpersonal context, leading to more serious ruptures and, eventually, to the dropout. The findings are discussed in terms of therapist responsiveness and of its role in the continuous negotiation of the working alliance.
Dropout and narcissism: an exploratory research about situational factors and personality variables of the psychotherapist
Authors: Oasi Osmano , Maggio Simone , Pacella Sara , Molgora Sara
Published: August 2019

The premature interruption of psychotherapeutic treatments is a significant phenomenon, with rates that can be above 50%, although differences emerge among studies. In general, the variables related to the psychotherapists have a significant effect on the treatment and a greater extent than the situational variables. In this study a multi-method research has been conducted to test the situations of impasse ending in dropout and the relationship between these situations and the covert narcissistic dimension of the therapist. Each participant was administrated the Impasse Interview, asking the therapist to focus on a salient or recent dropout case, and the Hypersensitive Narcissism Scale. The linguistic analysis of the interviews carried out with T-Lab produced 4 thematic clusters. Furthermore, as for the covert narcissistic dimension, 11 therapists reported a score below the average (Group A) and 9 scoring in the average (Group B). Finally, the association between the four clusters and the two groups of therapists was investigated. The therapeutic alliance and the emotional reaction of the therapist, influenced by his narcissistic dimension, represent key variables for the outcome of the therapy.
Ignatius
Authors: Stander H.F.
Published: August 2019

No abstract available.
Immanuel kant: Fundering vir die metafisika van die sedelikheid
Authors: Dreyer P.S.
Published: August 2019

No abstract available.
Eerste Hoofstuk
Authors: Dreyer P.S.
Published: August 2019

No abstract available.
Hoofstuk 6: Die boodskap van die boek
Authors: Potgieter J.H.
Published: August 2019

No abstract available.
Naskrif
Authors: Office Editorial
Published: August 2019

No abstract available.
Skrif en kerkorde - enkele opmerkings
Authors: Pont A.D.
Published: August 2019

No abstract available.
Origins of economic instability: Real, financial or both? - Part I: An account of Minsky's financial instability hypothesis
Authors: Hart J. S.
Published: August 2019

The 1990s have put the issue of global economic stability under the spotlight. This calls for a re-examination of the economic theory surrounding the subject. Here a three-fold classification is useful. The first grouping locates the source of stability in the workings of the real sector of the economy. A second, following Hyman Minsky, contends that instability arises in the financial sector. A third grouping draws on a distinction by Schumpeter to argue that any effective analysis of stability or instability requires a theoretical framework that integrates both the real and financial sectors at the most basic level. In the light of the current financial crisis which originated in South-East Asia, the second grouping appears most relevant. Part II will give an appraisal of Minsky's theory.