bluuebunny/crossref_metadata_2025 huggingface dataset:
Ameliorative Effect of Tapinanthus globiferus on Sodium Arsenite Induced Carcinogenesis in Canton-S strain of Drosophila melanogaster: In-vivo and In-silico Studies
Authors: Oche Jane-Rose , Dabak Jonathan D. , Johnson Titilayo O.
Published: December 2024

Tapinanthus globiferusis a hemi-parasitic plant that grows on vascular trees. It is often regarded as an economic menace due to the damages it cause on trees with economic values. However, despite the perception of the ever-green plant as an economic problem, traditional medicine makes use of the plant in the treatment of different diseases including cancer. This study aimed to investigate the anticancer property of the leaf of Tapinanthus globiferus using Drosophila melanogaster and to identify thepotential anticancer bioactive compounds. To determine a safe dose of the crude extract and fractions of T. globiferusto be used for the studies, thesurvival rates of the flies were evaluated at different concentrations (0, 0.5, 1.0 and 2.0 mg/10 g diet) for 14 days. Carcinogenesis was induced in Drosophila melanogasterusing sodium arsenite (SA) and the SA-exposed flies were treated with 1.0 mg/10 g diet of the three fractions for 10 days. Biochemical parameters of oxidative stress (hydrogen peroxide, non-protein thiol (NPSH), total thiol, nitric oxide, protein carbonyl, malondialdehyde and glutathione-s-transferase (GST) activity), cell viability, negative geotaxis and gene expressions (p53 and Ras) were used to evaluate the ameliorative activityof the fractions on the carcinogenic effects of SA in the flies. HPLC-DAD analysis was carried out to determine the bioactive compounds present in the active fraction. Molecular Docking analysis of the compounds against selected cancer drug targets (VEGF-A and Ras) was done followed by ADMET studies. The results of biochemical analyses showed that the three fractions ameliorated the SA-induced carcinogrnic effects in the flies. The butanol fraction showed higher ameliorative activity. HPLC-DAD results showed the presence of hydroxybenzoate derivatives, hydroxycinnamate derivatives and flavonoids in this fraction. Result of the molecular docking shows that Rutin had higher binding with HsVEFGA with score of -9.793 kcal/mol and with DmVEFGA with score of -8.890 kcal/mol, compared to the standard inhibitor. Also, isoquercetin had higher docking score compared with the standard inhibitor drug of Ras protein of both humans(-8.587 kcal/mol) and Drosophila melanogaster (-11.883 kcal/mol). Both compounds showed low bioavailabilty as drug candidates. While rutin showed class 5 toxicity, isoquercetin showed class 4 toxicity. This suggests that Tapinanthus globiferus may possess potential anticancer attributes that can be associated to the presence of the polyphenolic compounds, which could be explored further for the purpose of anticancer drug design.
SEMIOTIC ANALYSIS OF THE REPRESENTATION OF BACPACKER TOURISM IN THE FILM "TRINITY, THE NEKAD TRAVELER"
Authors: Shidqy Dhiya’u , Arini Erni Zulfa
Published: December 2024

Abstract: As an archipelagic country with enormous tourism potential, it can boost state income through foreign exchange. Even though data on foreign tourist visits in 2023 increased 98% compared to 2022 and is dominated by private visits, Indonesia is only ranked 4th in ASEAN regarding tourism visits. The stimulus for building a tourism image is the spearhead for national tourism, one of which is through the medium of film. "Trinity, The Nekad Traveler" is a film that focuses on national tourism by presenting the backpacker concept. This research aims to determine the movie "Trinity, The Nekad Traveler" in representing backpacker travelers and backpacker tourism using a semiotic analysis approach modeled by Charles Sanders Peirce. The research results show that based on signs, objects, and interpretations in various scenes, the film "Trinity, The Nekad Traveler" represents the characteristics of backpackers and backpacker tourism.
Keywords: backpacker; tourism; film; semiotics
 
Abstrak: Sebagai negara kepulauan dengan potensi wisata yang sangat besar yang mampu mendongkrak pendapatan negara melalui devisa. Sekali pun data kunjungan wisatawan mancanegara tahun 2023 meningkat 98% dibanding tahun 2022 dan didominasi oleh kunjungan personal, Indonesia hanya menempati urutan ke-4 di ASEAN dalam hal kunjungan pariwisatanya. Stimulus tentang pembangunan citra pariwisata menjadi ujung tombak terhadap eksistensi pariwisata nasional, salah satunya dengan media film. “Trinity, The Nekad Traveler” merupakan salah satu film yang mengangkat tentang pariwisata nasional dengan mengemas konsep backpacker. Tujuan penelitian ini adalah mengetahui film “Trinity, The Nekad Traveler” dalam merepresentasikan backpacker traveler dan backpacker tourism dengan pendekatan analisis semiotika model Charles Sanders Peirce. Hasil penelitian menunjukkan bahwa berdasarkan sign, object dan interprenant pada berbagai adegannya, film “Trinity, The Nekad Traveler” merepresentasikan tentang karakteristik backpacker traveler dan backpacker tourism.
Kata Kunci: backpacker; pariwisata; film; semiotika
MICROBIOLOGICAL PROFILE OF CLINICALLY DIAGNOSED VAGINOSIS IN TERTIARY CARE HOSPITAL
Authors:   Assistant Professor- DR.BVP RMC PIMS (DU) Loni, Maharashtra, India., Khan Tadvi , Kauser Saleha ,   Assistant Professor- DR.BVP RMC PIMS (DU) Loni, Maharashtra, India., Ahmed Khan Mukhtar ,   Assistant Professor- DR.BVP RMC PIMS (DU) Loni, Maharashtra, India., Bhalerao Deepika ,   Professor DR.BVP RMC PIMS (DU) Loni, Maharashtra, India., Vaidya Kinikar Anagha ,   Professor DR.BVP RMC PIMS (DU) Loni, Maharashtra, India., Roushani S. ,   HOD & Professor DR.BVP RMC PIMS (DU) Loni, Maharashtra, India., Padekar Hira ,   Associate Professor- DR.BVP RMC PIMS (DU) Loni, Maharashtra, India., Sinha Rohit ,   Assistant Professor- DR.BVP RMC PIMS (DU) Loni, Maharashtra, India.
Published: December 2024

Introduction: The Normally vaginal flora contains Lactobacillus more in numbers and Gardnerellavaginalis in low numbers. When Gardnerellavaginalisis outnumbered, it causes a condition called bacterial vaginosis. Lactobacillus species maintains the acidic pH of the adult vagina protecting from various infections. In pre-pubertal and postmenopausal vagina, lactobacilli are scanty, which predisposesto many infections. Around 75% of women in reproductive age will have at least one episode of candidiasis.

Aim & Objectives: 1. To know Nugents score with Grams staining in received samples. 2. To know the culture outcomes of received samples.

Material &Methods: This is a Retrospective study of one year duration (July 2021- June 2022). Vaginal swabs of patients received in Microbiology Department were processed.

Results: Nearly half of the samples based on Nugent score were categorized as normal flora, 86 (48.31%), 38 (21.34%) as having intermediate flora and 54 (30.33%) as bacterial vaginosis. A total of 178 samples were processed out of which 92(51.68%) were culture positive. Out of 178 samples 36 (20.22%) isolates were Candida spps. and 56 (31.46%) were bacterial isolates. All Gram-positive isolates were sensitive to vancomycin (100%). E. coli were most sensitive to imipenem, meropenem (88.46%).This is study concluded that microbiological profiles of vaginosisnecessary to diagnose and treat the patients.In this studyAerobic vaginitis is most commonly caused by E.coli and Vulvovaginal Candidiasis most commonly caused by Candida albicans (25%), which can be easily treated.
STRATEGIC MANAGEMENT OF START-UP UNIVERSITIES: A CASE STUDY OF UNIVERSITAS PROF. DR. DR. DR. M HAFIZURRACHMAN, SH, MPH (UHAFIZ) IN TRANSFORMING HIGHER EDUCATION IN CIANJUR, WEST JAVA, INDONESIA
Authors:   Accounting Academic Dean UHAFIZ, Cianjur, Indonesia., Gomar Sinaga Hendrik , Hafizurrachman Syarief Muhammmad ,   Founder UHAFIZ, Cianjur, Indonesia.
Published: December 2024

This paper examines the strategic management of Universitas Prof. Dr. Dr. dr. M Hafizurrachman, SH, MPH (UHAFIZ), a start-up university in Cianjur, West Java. The study explores how UHAFIZ uses strategic planning to overcome challenges and foster regional development through higher education. A qualitative case study approach is used, including document analysis, semi-structured interviews with university leaders and stakeholders, and on-site observations. Data were collected from university reports, strategic plans, and stakeholder interviews. Findings reveal that UHAFIZ has aligned its academic programs with local and global needs, focusing on innovation, leadership, and community engagement. Strategic partnerships have addressed resource and infrastructure challenges. The case study concludes that strategic management, leadership, and stakeholder involvement are critical to UHAFIZs success, demonstrating that start-up universities can positively impact regional education and development.
ROLE OF TITANIUM IN PROSTHODONTICS
Authors:   Professor, Department of Prosthodontics, Royal Dental College, Palakkad, Kerala., P.A Shajahan , Raghavan Rohit ,   Professor and Head, Department of Prosthodontics, Royal Dental College, Palakkad, Kerala., P.P Faseela ,   Post Graduate Student, Department of Prosthodontics, Royal Dental College, Palakkad, Kerala.
Published: December 2024

Titanium has revolutionized the field of prosthodontics due to its exceptional properties. This light weight, yet incredibly strong metal has become a cornerstone in dental restorations. The basic properties of titanium like biocompatibility,corrosion, strength,shape memory etc. are discussed in detail. These properties of titanium make it the miracle metal in dentistry.
Survival Amidst the Forest: Exploring Leopard Depiction in Mannan Tales
Authors:   Assistant Professor, Department of English, SVR NSS College, Vazhoor, Kerala, Nair Veena R.
Published: December 2024

Mannan is an Adivasi community residing in forty-six settlements in Idukki, Ernakulam, and Thrissur districts of Kerala. Tales constitute a major part of their copious orature. A tale is woven between the storyteller and the listener, a well-knitted mantle, which on a close reading can unfold the anatomy of their life-land nexus. In various tales, animals of their forest become characters, with leopards playing a significant role in tales that depict the theme of survival. Leopard is the most terrifying image to an adivasi community that could endanger their life. In a sense, the fear of leopards represents the people’s fear of the dangers of the wild which they had to fight for survival. When people use the image of the leopard in their daily lives in the form of art forms and tales, they try to confront their fear. The tales are the simplistic narratives cultivated by unsophisticated people and, they are structured with the patterns from their own life. The paper traces how leopards are depicted in Mannan trickster tales and tall tales and how the depiction of leopards is related to Mannan life and survival in the forest.
Assessing the impacts of land use and climate change on streamflow generation in the Nowrangpur catchment based on the SWAT–land-use update tool
Authors: Kaur Sukhsehaj , Chavan Sagar Rohidas
Published: December 2024

Climate change and land-use change are two major factors that affect the hydrologic response of a river basin. Soil and Water Assessment Tool (SWAT) is a reliable method to model the hydrology of a river basin. The SWAT–land-use update tool offers a user-friendly interface for the incorporation of dynamic land-use changes into hydrological modeling. This paper evaluates the impacts of climate and dynamic land-use changes on streamflow generation in the Nowrangpur catchment encompassing Indravati dam, which is a major water-resources project in India. Calibrating the SWAT model involved updating land-use data from 1985 to 2015, yielding satisfactory results. The future land-use/land-cover changes were predicted using the cellular automata–artificial neural network model. Downscaled general circulation model data from ten climate models were utilized to predict climate-change impacts up to 2100. Projections indicate increased precipitation during the months from August to December with a more pronounced increase in the mid and far future. An uptrend in maximum and minimum temperatures for all months is observed in the far-future relative to the baseline period. Furthermore, the streamflow predictions indicate a near-future decrease in total annual streamflow, followed by an increase of up to 41% in the mid and far future.
Traços do Programa Ciência é Dez (C10) como política pública a partir da produção documental da Capes
Authors: Guimarães Guerra Gama Simone , Antunes Soares Félix Alexandre , Ferreira Marcello , Da Silva Filho Olavo Leopoldino
Published: December 2024

Este artigo busca avaliar as ideias e os conceitos preponderantes a respeito do curso Ciência é Dez (C10), ofertado pelo sistema Universidade Aberta do Brasil, gerido pela Fundação de Aperfeiçoamento de Pessoal de Nível Superior, sob a perspectiva de sua organização como programa em associação de instituições públicas de ensino superior ofertantes. Como referencial teórico, utilizou-se a Abordagem do Ciclo de Políticas Públicas, notadamente o conceito de contexto de produção, além de concepções acerca de formação continuada de professores e ensino de ciências. Metodologicamente, a pesquisa é caracterizada como documental, descritiva e interpretativa; e utilizou técnicas da Análise de Conteúdo e Análise Textual para codificação e categorização dos dados qualitativos, com o auxílio dos softwares IRaMuTeQ e SOBEK. O corpus é proveniente dos arquivos da CAPES, em que foram localizados 248 documentos a respeito do curso com referência ao período entre os anos de 2010 e 2022. Os principais resultados obtidos foram a constatação da presença de duas categorias predominantes: 1) Programa C10 – Aspectos Gerenciais; e 2) Aspectos Políticos, Filosóficos e Pedagógicos da Educação. Em decorrência do léxico das categorias e de processos inferenciais, foi possível determinar traços constitutivos do Programa, tendo concluído, destacadamente, que as ideias predominantes estão pautadas em modelo de formação de professores que privilegia a conexão com a sala de aula e seus aspectos práticos, fomentando o ensino de ciências baseado na investigação e na pesquisa. Como incongruência, verificaram-se traços de racionalidade técnica no gerenciamento por parte da CAPES, o que se opõe aos pressupostos programáticos anunciados.
Politik Anggaran Pinjaman Daerah dalam Pembiayaan Pembangunan di Kabupaten Manggarai Tahun 2021-2023
Authors: Syafruddin Akhmad , Nami Yohanes Jimmy , Luju Kornelia
Published: December 2024

Regional Loans are an alternative funding instrument used by the Manggarai Regency government, East Nusa Tenggara (NTT) Province, to finance regional development. Political support and the interests of political parties can influence the negotiation process in obtaining legislative approval. This research aims to determine how regional loans work and analyse the relationship between the executive and legislature in the political discussion and approval process in formulating regional loans. This research uses a qualitative approach and qualitative descriptive method, collecting information through primary and secondary data and determining informants using purposive techniques. The research results show that there are strong political dynamics, and there are differences in the interests of the views of each faction in discussions at the DPRD plenary meeting. The strength of the factions supporting the government dominates the discussions, further strengthening the regent's proposal for regional loans. The power of the executive and the majority of factions supporting the government are a strong driving force in smoothing the success of regional loans in Manggarai Regency. The faction that does not approve can finally accept and approve the loan, noting that regional loans must benefit the interests of development and community welfare.
Transboundary nature protection as a means of preserving peace in Kosovo and neighboring regions
Authors:   University of Prishtina, Faculty of Mathematical and Natural Sciences, Department of Geography, Prishtina, Kosovo, Ejupi Arsim , Stiperski Zoran ,   University of Zagreb, Faculty of Science, Department of Geography, Zagreb, Croatia, Bytyqi Valbon ,   University of Prishtina, Faculty of Mathematical and Natural Sciences, Department of Geography, Prishtina, Kosovo
Published: December 2024

This article contains insights into the creation of transboundary protected areas, their features, the relationship between nature protection and achieving and maintaining peace in a global and regional context. Using various cases, the goals, benefits, and advantages of transboundary cooperation are elaborated, with a particular emphasis on the areas of nature protection and peace. Regardless of the causes that lead to disputes and conflicts between states, many of them occur in transboundary areas. Conflicts over disputed border lines are becoming more frequent, and some of them pose a serious threat to important biodiversity and geodiversity sites around the world. Therefore, the concept of peace parks offers an alternative to tensions in crisis and conflict hotspots via joint management of natural heritage and the environment, involving multiple stakeholders, with local communities playing an important role as the first and immediate beneficiaries of such cooperation. Despite the numerous benefits offered by transboundary nature protection, there are only a few examples in the Balkans, mostly in the initial stages. Despite its relatively small territory, Kosovo has very heterogeneous natural conditions, with various morphological units. Some of them extend beyond its borders, thus offering numerous opportunities for transboundary cooperation for the protection of natural heritage and the environment, which would transcend its narrower goal and serve as a means of establishing and preserving peace.
Application of Sensitivity Analysis and Super-Efficiency DEA Models on Efficiency Evaluation of Public Sector Banks in India
Authors: Simon Miriam Kalpana , Prakash Venu
Published: December 2024

The assessment of performance or efficiency is an essential step in the production process. Performance and efficiency evaluations can be done using parametric or non-parametric approaches. When analysing the effectiveness of similar organisations, also known as Decision Making Units (DMUs), with many inputs and outputs, one of the most widely used non-parametric methodology is Data Envelopment Analysis (DEA), which is based on a linear programming approach. Inefficient units are benchmarked (peers) and efficiency scores are provided by DEA for each DMU. Based on the number of peers, the Decision Making Units might then be ranked. A Tie between ranks, however, can happen. Andersen-Peterson’s (1993) model aids in breaking the tie. The super-efficiency model produces an infeasible result, which is confirmed by applying the prerequisites for infeasibility identification put forth by Seiford & Zhu (1999). In this paper, we present the results of our empirical investigation of Public Sector Banks in India during the 2019–20 period, focussing on three inputs and two outputs. We used variable return to scale (VRS) assumption based Banker Charnes and Cooper (BCC) and super-efficiency models, and also identified the infeasibility problem and performed sensitivity analysis. Finally, a stability region was constructed.
Incidence of Deliberate Self-Harm in Hong Kong Before and During the COVID-19 Pandemic: Population-Wide Retrospective Cohort Study
Authors: Luk Luke Y F , Ching Christie J Y , Yip Tsz Fung , Chan Sunny C L , Lam Catherine Y T , Lam Elizabeth T C , Yue Serena R B , Pang Hoi Ching , Wong Janet Y H , Wong Carlos K H , Tong Chak Kwan , Yamamoto Tafu , Rainer Timothy H , Wai Abraham K C , Ho Joshua W K
Published: December 2024

Background

COVID-19 ended on May 5, 2023, and since then Hong Kong reported increased mental distress, which was speculated to be from the policies implemented during the pandemic. Despite this, longitudinal surveillance of deliberate self-harm (DSH) incidences throughout the pandemic in Hong Kong remained insufficient.

Objective

The objective of this study was to outline the changes in DSH incidences before and during the COVID-19 pandemic in Hong Kong, with respect to sex, age, and co-occurring mental health issues.

Methods

A quasi-experiment was conducted using an interrupted time series design to estimate the impact of the pandemic on DSH-related emergency department (ED) visits. This design enabled the estimation of DSH-related ED visits based on prepandemic data from 2016 to 2019, assuming the pandemic had not occurred, and allowed for a comparison with observed DSH-related ED visits during the pandemic. The descriptive results were reported as the observed monthly DSH-related ED visits and observed incidence ratios during the pandemic. Afterwards, a negative binomial model was fitted to the prepandemic data (2016‐2019) and adjusted for temporal trends, seasonality, and population variation to estimate the expected monthly DSH-related ED visits and adjusted incidence ratios (aIRs).

Results

Between January 2016 and December 2022, a total of 31,893 DSH episodes were identified. Initial descriptive analysis showed a significant difference in demographic characteristics (sex) and clinical characteristics (death within 28 d, diagnoses of co-occurring mental health issues, public assistance pay code, and triage level). Subsequent interrupted time-series analysis demonstrated significantly increasing trends in comparison with the prepandemic period. As reported in the aIRs among young adult males (aIR in 2020=1.34, P=.002; 2021: aIR=1.94, P<.001; and 2022: aIR=2.53, P<.001), adult males (aIR in 2020=1.58, P<.001; 2021: aIR=2.64, P<.001; and 2022: aIR=3.13, P<.001), adult females (aIR in 2020=1.13, P=.01; 2021: aIR=1.52, P<.001; and 2022: aIR=1.64, P<.001), and older male adults (aIR in 2020=1.53, P<.001; 2021: aIR=2.37, P<.001; and 2022: aIR=3.01, P<.001).

Conclusions

The average annual DSH-related ED visits increased during the pandemic period. Therefore, there is a need to raise awareness for such vulnerable groups in Hong Kong to prepare for postpandemic spillover.
Methods For Analytical Validation Of Novel Digital Clinical Measures: An Evaluation Using Real-World Datasets (Preprint)
Authors: Turner Simon , Floden Lysbeth , Fromy Piper , Langford Joss , Potter Andrew , Simmatis Leif , Daza Eric J , Troeger Kathleen ,   the STAGES cohort investigator group
Published: December 2024

BACKGROUND

Sensor-based digital health technologies (sDHTs) are increasingly used to support scientific and clinical decision-making. The digital measures (DMs) they generate offer significant potential to accelerate the drug development timeline, decrease clinical trial costs, and improve access to care. However, choosing appropriate statistical methodology when conducting analytical validation (AV) of a DM is complicated, particularly for novel DMs, for which appropriate, established reference measures may not exist. More understanding of, and a standardization of approach to, AV in these scenarios is needed.

OBJECTIVE

In a prior simulation study, three statistical methods were tested for their ability to estimate a simulated relationship between a sDHT-derived DM and several clinical outcome assessment (COA) reference measures. The aim of this work was to assess the feasibility of these methods’ implementation in real data, and to examine the impact of AV study design factors on the relationships estimated.

METHODS

Four real-world datasets, captured using sDHTs, were used to prepare hypothetical AV studies that represented a range of scenarios with respect to three key study design properties: temporal coherence, construct coherence and data completeness. For each hypothetical study, two-factor, correlated-factors confirmatory factor analysis (CFA) models, and a combination of simple and multiple linear regression models, were built using the DM and reference measure data. The factor correlation, R2 and adjusted R2 statistics were calculated, in addition to the Pearson Correlation Coefficients (PCCs).

RESULTS

The majority of CFA models exhibited an acceptable fit according to the majority of the fit statistics employed, and each model was able to estimate a factor correlation. For each model, these correlations were greater than or equal to the corresponding PCC in magnitude. Correlations were strongest in the hypothetical studies with strong temporal and construct coherence.

CONCLUSIONS

The performance of the measures shown in this work supports the feasibility of the selected statistical methods when implemented in real-world data. Our findings in particular support the use of CFA to assess the relationship between a novel digital measure and a COA reference measure. The observed impact of AV study design factors on the relationships estimated allowed the authors to determine practical recommendations to aid in appropriate study design for AV of novel digital measures. By utilizing a standardized methodology for evaluating novel digital measures, sDHT developers, biostatisticians and clinical researchers will be able to navigate the complex validation landscape more easily, with more certainty, and with more tools at their disposal, expediting the pathway to validation and regulatory review.
Mitologie napoleoniche: da Vincenzo Monti a Gabriele Rossetti
Authors: Spaggiari William
Published: December 2024

Il contributo intende mettere in luce i caratteri e le modalità della poesia encomiastica di primo Ottocento, che ha al centro la figura e le imprese di Napoleone; si sofferma in particolare sui testi di Vincenzo Monti, il principale promotore a Milano di questa “mitologia” del condottiero e dell’eroe, e su quelli del giovane Gabriele Rossetti, che a Napoli compie il proprio apprendistato poetico durante il regno di Giuseppe Bonaparte; e individua le linee del revival napoleonico (alimentato dalle speranze riposte nel figlio dell’imperatore) che, grazie all’intensa attività delle tipografie della Svizzera italiana, si sviluppa nei primi tempi della Restaurazione.
Memorie della Mascheroniana di Vincenzo Monti nel Trionfo della Libertà di Alessandro Manzoni: una riflessione
Authors: Tanzi Imbri Barbara
Published: December 2024

Composti a breve distanza l’una dall’altro, la Mascheroniana e il Trionfo della Libertà presentano numerose tangenze stilistiche, lessicali e tematiche, che tuttavia non implicano l’adesione da parte di Manzoni alle posizioni ideologiche del proprio modello, che è tale soltanto sul piano letterario. Il presente contributo offre un approfondimento sul rapporto tra i due poemetti confermando la straordinaria indipendenza di prospettiva del giovane Manzoni, nonché la sua originalità espressiva, già più volte rilevate dalla critica, che proprio i contatti testuali più stringenti contribuiscono a evidenziare.
Cuando lo abyecto estalla: figuraciones de la violencia contra las mujeres en «La muerte tenía nuestros dedos» de Jennifer Thorndike
Authors: León Torrez Virginia
Published: December 2024

A diferencia de otros textos literarios en torno a la violencia contra las mujeres indígenas durante el conflicto interno armado en Perú (1980-2000), el cuento «La muerte tenía nuestros dedos» de Jennifer Thorndike ofrece otras figuraciones de la violencia sexual además de la violación. Esto es la esterilización forzada de mujeres en una comunidad rural. A partir del análisis del narrador en este texto me propongo indagar en los sentidos que subyacen a esta forma de violencia y las posibles estrategias de resistencia que el cuento habilita. En este sentido, a través de las nociones de abyección y asco analizaré las asociaciones entre el cuerpo de las mujeres y la basura. Finalmente, mediante la metáfora del chasquido (Ahmed 2018) reflexionaré sobre la acción política de estas escrituras.
Cartas, epistolaridad e interlocución en la obra de Carmen Martín Gaite
Authors: Calvi Maria Vittoria
Published: December 2024

El presente artículo explora las dimensiones de la epistolaridad en la obra de Carmen Martín Gaite a partir de las teorizaciones de autores como Altman (1982) y Guillén (1998). En particular, se estudiarán la comunicación epistolar como modalidad de interlocución; el valor de la carta como texto, en el marco del proceso de ficcionalización; y la carta en su materialidad como forma de presencia dentro de la escena enunciativa. Se aportarán ejemplos extraídos tanto de algunas novelas (Retahílas, Fragmentos de interior, El cuarto de atrás y Nubosidad variable) como de las cartas personales de la autora, recopiladas en el VII volumen de las Obras completas, con especial referencia a la correspondencia con Juan Benet.
Lectura metaliteraria de «La oficina»
Authors: Licci Chiara
Published: December 2024

Este artículo propone un análisis discursivo del relato «La oficina» (1954) de Carmen Martín Gaite, en el cual se evidenciarán las estrategias discursivas que utiliza el texto para dejar abiertas ranuras que posibiliten al lector, manipulado emocionalmente, participar en él, fungiendo de buen espejo. Se procurará de mostrar la presencia de un nivel de sentido implícito de naturaleza metaliteraria que pondrá en escena el contraste entre un discurso literario superficial, vacío y  aquel propio de la Generación del 50, profundo y auténtico.
Prefiguraciones literarias en la correspondencia de Carmen Martín Gaite con Juan Benet: «La búsqueda de interlocutor», El proceso de Macanaz y Retahílas
Authors: Teruel José
Published: December 2024

Este artículo analiza las prefiguraciones de tres títulos de Carmen Martín Gaite que se configuraron o iniciaron en la década de 1960 –«La búsqueda de interlocutor» (1966), El proceso de Macanaz (1963-1969) y Retahílas (1965-1973)– a través de la Correspondencia que mantuvo con Juan Benet y a partir de la noción de epitexto de Gérard Genette (1987). Ello permitirá dilucidar con mayor complejidad su idea de la búsqueda de interlocutor asociada a la busca literaria del modo y cómo en el taller de la escritora conviven, en un periodo de corta duración, distintas modalidades y mezclas de escritura (ensayo literario, investigación histórica y ficción), que demuestran preocupaciones similares, y una concepción de su obra como un texto unitario que inútilmente se deja compartimentar.
Sentidos implícitos en la representación de la violencia contra las mujeres en El mapa de los afectos
Authors: Sánchez Bourquin Laura
Published: December 2024

Mediante el análisis discursivo de tres episodios de El mapa de los afectos protagonizados por tres personajes femeninos, este artículo mostrará cómo estas mujeres ocupan el espacio simbólico de la casa de una manera que preconiza las violencias sufridas por ellas, así como sus victorias sobre estas. Violencias y victorias que, como se verá, revelan también los sentidos implícitos, de carácter autorreferencial, de la novela de Ana Merino.
Crop Price Prediction
Authors: S Mr. Srikanth , N Shekhar S , Gowda Sadananda , H Rahul , R Ravi
Published: December 2024

Abstract: Accurate crop price prediction is pivotal for optimizing agricultural decision-making and ensuring economic stability
for farmers, traders, and policymakers. In this paper, a Random Forest based machine learning framework is proposed to
forecast crop price up to 80% accuracy. Advanced feature engineering techniques such as percentile based methods are used to
reduce the outlier effects and lag variables to maintain sequence patterns and dependencies.
To enhance usability and accessibility, the predictive model is deployed through a Flask-based web application, providing an
intuitive user interface for real-time interaction. Total of this implementation combines the methodologies of ML with practical
engineering to cope with the versatilities of agriculture commodity price prediction. -- the architecture of the designed system has
a great potential for developmental transformation, towards making these systems into data-driven businesses and economic
actors based on sustainable, renewable agricultural transformation systems in the larger scope of precision agriculture,
economic resilience, etc
Revolutionizing Human-Computer Interaction: AI-Driven Voice Assistants Integrating Python, NLP, APIs and Machine Learning for Adaptive and Scalable Desktop Solutions
Authors: S Indudhara , Nayak Sankhya N , M Dhanush D , D Aavishkar , Navale Aditya A
Published: December 2024

Abstract: This survey focuses on advancements in AI-based voice assistants for desktop applications, emphasizing their
transformative role in enhancing human-computer interaction. Key themes include leveraging Python and open-source libraries
for functionalities such as speech recognition, natural language processing (NLP), and task automation. The systems
demonstrate integration with APIs and external services for diverse applications, ranging from personal productivity to
entertainment and smart device control. Each paper highlights user-centric features like customization, adaptability, and
intuitive interfaces while addressing challenges like system scalability, security, and user privacy. Collectively, these works
underline the potential of AI- driven solutions to simplify daily tasks and expand the capabilities of modern computing systems.
Ovista: ML-Based Web Application for PCOS Detection
Authors: S Sreedevi , Y Abhishek J , K Abhishek , Shetty Chintan C , M Dhanush H
Published: December 2024

Abstract: Polycystic Ovary Syndrome (PCOS) is a common endocrine disorder affecting reproductive-age women, characterized
by various symptoms and irregularities. This ovista proposes a comprehensive PCOS detection framework that combines
numerical and image-based features. The numerical model uses a dual-pronged system: symptom-based prediction to identify
PCOS presence, and parameter-based prediction to categorize its severity into low, medium, or severe. Built using machine
learning algorithms, it offers an accurate diagnosis. Additionally, deep learning techniques are applied to analyze medical
images for PCOS patterns, further enhancing detection accuracy. This multi-modal approach provides a holistic diagnostic tool,
helping clinicians understand PCOS severity and enabling personalized treatment strategies.Ovista is a trusted companion in
detecting and managing Polycystic Ovary Syndrome (PCOS). Designed with care and precision, Ovista leverages advanced
technology to empower women by providing accurate insights into their health. The name Ovista is derived from the
combination of "Ova" and "Vista". "Ova," meaning egg, represents the core focus on women's reproductive health,
particularly issues related to the ovaries such as PCOS. "Vista" signifies vision or perspective, highlighting the platform’s
mission to provide a clear and comprehensive understanding of health. Together, Ovista symbolizes a visionary approach to
empowering women with insights and solutions for managing PCOS effectively.
BENIGNO OMAR GUERRERO OROZCO (1946-2023)
Authors: Vicher Diana
Published: December 2024

El 12 de noviembre de 2023 partió el gran pensador latinoamericano de la administración pública, Omar Guerrero. El propósito de este breve documento es realizar una aproximación a la trayectoria de Omar Guerrero en la enseñanza y la investigación en la administración pública, destacando algunos de los hechos nodales que permitan que se conozca mejor el proceso de su ascenso como la figura referente del pensamiento latinoamericano en la materia.
FORMACIÓN Y PARTICIPACIÓN CIUDADANA DE LOS JÓVENES UNIVERSITARIOS DE LA REGIÓN DE LOS LAGOS, CHILE
Authors: Alarcon-Henríquez Nancy , Ganga-Contreras Francisco , Aravena Niño Bastián , Viancos Patricio
Published: December 2024

Entre las tareas que deben asumir las universidades, está la de lograr procesos educativos que contribuyan a la formación de ciudadanos con valores democráticos, vinculados con las comunidades y su entorno. El estudio investiga la participación ciudadana entre jóvenes universitarios en la Región de Los Lagos, Chile. Utilizando un enfoque cuantitativo, se utilizó el cuestionario de conductas de participación Vergara-Lope y Hevia de la Jara 2012), aplicándolo a una muestra por conveniencia de 208 estudiantes. Los resultados muestran altos niveles generales de participación, especialmente en dimensiones como la asociativa-opinativa y la cívica, pero baja participación en actividades partidarias. No se encontraron diferencias significativas entre las universidades, excepto en la dimensión electoral, donde la Universidad San Sebastián mostró menor participación. Estos hallazgos subrayan la importancia de fortalecer la formación cívica en la educación superior, crucial para el desarrollo democrático y la promoción de un compromiso democrático más robusto entre los jóvenes.
POLÍTICAS PÚBLICAS, CAPITALISMO DEL CONOCIMIENTO Y EMPRESA EN ESTADOS UNIDOS: EL DECLIVE DE LA CORPORACIÓN CLÁSICA
Authors: Barrera Rodríguez Seida , Domínguez López Ernesto
Published: December 2024

El artículo analiza la transformación del sistema empresarial estadounidense a partir del último cuarto del siglo XX hasta el primer cuarto del siglo XXI. Estudia las condiciones de contorno para la evolución de las empresas estadounidenses como parte de la formación del capitalismo del conocimiento con énfasis en las políticas públicas conformadas durante el período que impactaron directamente a las empresas. En específico estudia la emergencia de la compañía de responsabilidad limitada (LLC) en el contexto de los cambios institucionales generados por esas políticas públicas y determina empíricamente que esta forma empresarial se ha convertido en ampliamente dominante. Este hallazgo contribuye a sustentar la tesis de Gerald Davis de la desaparición de la corporación clásica, con algunos matices. Se plantea que este cambio es fruto de una transformación integral de la economía, la política y la administración empresarial y pública en la transición hacia el capitalismo del conocimiento.
ANÁLISIS DEL DESEMPEÑO DEL CONSEJO CONSULTIVO DEL INAI: UNA VISIÓN DESDE EL ENFOQUE DE LA GOBERNANZA EN MÉXICO
Authors: Uvalle Berrones Ricardo
Published: December 2024

El objetivo del presente artículo consiste en analizar el rol del Instituto Nacional de Acceso a la Información y Protección de Datos Personales (INAI). ¿En qué medida el Consejo Consultivo del INAI incentiva el fortalecimiento de este órgano para que las libertades ciudadanas sean protegidas cuando se afectan los derechos relacionados con el ejercicio de acceso a la información y la seguridad de los datos personales? La hipótesis que se plantea es que la tarea deliberativa y argumentativa del Consejo Consultivo es fundamental para enriquecer la toma de las decisiones por parte de los consejeros que integran el pleno del INAI, al observar, criticar y recomendar acciones que deben orientarse hacia una mejor aplicación de las disposiciones que aluden al derecho de acceso a la información y la protección de los datos personales, en un marco de protección y seguridad que se sustenta en la institucionalidad de los valores democráticos.
TRANSPARENCIA EN LA CONTRATACIÓN PÚBLICA EN ECUADOR: UN ANÁLISIS DE LA DEMANDA DE ACCESO A LA INFORMACIÓN
Authors: Jara Iñiguez Irma , López Sofía , Hidalgo Mario , Olivares Alejandro
Published: December 2024

Esta investigación tiene como objetivo identificar cuáles son las necesidades de los ciudadanos ecuatorianos sobre derecho de acceso a transparencia e información en la contratación pública, analizando las solicitudes de acceso a la información realizadas al Servicio Nacional de Contratación Pública (SERCOP) entre 2018 y 2022. Mediante un análisis documental y entrevistas a expertos y actores clave, se determinaron necesidades no cubiertas por la transparencia activa del SERCOP, como expedientes detallados, especificaciones de proveedores adjudicados, informes de reclamos y denuncias interpuestas y anexos contractuales, con un interés organizacional y para control social. Este trabajo aporta argumentos sobre la evolución de las necesidades ciudadanas de información en contratación pública, destacando áreas donde la transparencia debe fortalecerse para mejorar la toma de decisiones y la rendición de cuentas.
COMMUNICATION AND NETWORK AS TWO TECHNOLOGIES OF POLITICAL ORGANIZATION OF MAN AND SOCIALITY
Authors:   Institute of Sociology of the Federal Center of Theoretical and Applied Sociology of the Russian Academy of Sciences, MIKHAILENOK O.M. , NAZARENKO A.V. ,   Institute of Sociology of the Federal Center of Theoretical and Applied Sociology of the Russian Academy of Sciences
Published: December 2024

The purpose of the article is to clarify the meaning of the phenomena of "communication" and interpersonal "network interaction",
to separate their boundaries, definitions and evolutionary prospects in terms of the political organization of man and sociality.
Based on the presented duality of definitions, the authors substantiate that the information space is replete with seemingly mutually exclusive narratives about the life of people in the "connected world", in the "human web", in the "network society" and at the same time about the life of "free", "independent", "individual". The authors mark that an opportunity opens up to assess the deep essence, content, direction, limits and prospects of information circulating between people in the context of the organization of both the person himself and any local or global sociality created by him.
As a result, the key concept of the emerging logical dichotomy of “connectedness – freedom” becomes precisely “connectedness”, which is capable, under certain conditions, of reconciling “freedom” and “independence”,
balancing them with “interaction” and “interdependence”. The study and structuring of the essence of the meanings of the phenomena of “communication” and “network interaction” allows us to abstract the boundaries and, in the context of information exchange, consider them as equivalent concepts.
In conclusion, it is concluded that in the modern conditions of global sociality, on the one hand, a person is puzzled by the independence that has fallen on them as a result of the final collapse of illusions regarding the ability of any external third-party hierarchical systematization of sociality and formalization of oneself in it in one capacity or another; on the other hand, he gradually comes to understand that his own independence still has certain boundaries, determined by his belonging to a certain general local or global social.
LABOR PRODUCTIVITY: INDICATORS AND DIRECTIONS OF ECONOMIC DEVELOPMENT IN THE RUSSIAN REGION
Authors:   Non-profit organization "Fund for Industrial Development of the Orel Region", KOMAREVTSEVA O.O.
Published: December 2024

The purpose of the article is to analyze the indicators and
activities of the implementation of the national project "Labor Productivity" in the Orel region and to present promising proposals aimed at increasing the sustainable development of the region's economy.
The theoretical analysis of Russian and foreign studies of the economic category "labor productivity" made it possible to structure its distinctive features. The research methodology is based on the assessment of basic indicators characterizing the development of the region and the presentation of the results of the implemented activities within the framework of the studied project in the Orel region in the field of labor productivity. Based on the factor analysis of the data, the total economic effect and tax deductions of enterprises that participated in the implementation of the studied project in the region during 2021-2024 are presented. An assessment of the impact of labor productivity on the formation of sustainable development of the Orel region economy is carried out.
The feasibility of allocating state measures to support the development of labor productivity and receiving additional tax deductions to the regional budgets is established. The features and tools of rational regional development of production are structured, which make it possible to increase labor productivity in the region through the introduction of the project-program method. The main advantage of the study is the practical study of the issue of increasing labor productivity in the regional economy. Specific measures are proposed that create the necessary conditions for the effective implementation of the national project "Efficient and Competitive Economy" from 2025 to 2030 in the Orel Region. It is noted that their implementation will optimize production systems and increase revenues to regional budgets due to the growth of tax deductions. And will reduce the level of labor shortage, harmonizing spatial inequality in the region as well.
"POSTCLASSICAL EMPIRE" AS A TYPE OF STATE IN SCIENTIFIC DEBATE AND INTERNATIONAL REALITY
Authors:   Central Russian Institute of Management, Branch of RANEPA, BALASHOV A.N. , LIVTSOV V.A. ,   Central Russian Institute of Management, Branch of RANEPA
Published: December 2024

The purpose of the work is to study the type of state designated in domestic and foreign political science theory by the concept of "postclassical empire".
Subject of the research. Subjective characteristics of the "postclassical empire" during the formation of a new version of the world order in the context of globalization processes.
The methodological basis of the study is a combination of methods of analysis and political discourse of the use of imperial methodologies for constructing foreign policy strategies in the geopolitical space. The evolution of ideas about imperial foreign policy traditions in the industrial and post-industrial societies of the 20th-21st centuries (historical method) is analyzed. A comparativist analysis of the main scientific ideas about the typical features and specifics of the foreign policy of neo-imperial states in the context of the development of the international relations system is presented.
It is substantiated that the emergence of the typology of the "postclassical empire" is due to the political and ideological mimicry of supporters of the use of imperial methodologies for constructing foreign policy strategies during the Cold War and the post-bipolar world era.
At present, such approaches continue in the desire to overcome the crisis of promoting modern globalist projects by turning to the potential of the imperial ideological and political heritage. Along with this, the need for a rational understanding of the phenomenon of neo-imperial tendencies in the modern geopolitical space is argued.
As a result, based on the results of the study, a conclusion is formulated about the possibility of reviving the concept of empire, primarily as a phenomenon of political theory. At the same time, the prospects for its practical implementation will be determined by the balance of relations between national and international political entities of the post-bipolar era.
Informality as deviancy: the problem of difference in the Decent Work Agenda
Authors: Rowland Alisson
Published: December 2024

More than half of workers globally are informal workers; operating in non-standard, temporary employment that is often, but not always, poorly paid and unprotected. The Decent Work Agenda (DWA), pioneered by the International Labor Organization (ILO), has been broadly adopted to bri- dge the concerns of workers and states by pursuing “Decent Work for all”. A core component of the DWA is the reduction of informality. Almost ten years later, however, informality is increasing in many countries. In this paper, I explore the conceptual foundation of the DWA by asking: how does the ILO understand “work” in their 2015 Decent Work Agenda? What are the consequences for those whose rights are protected within global governance projects? I compile a corpus of 36 ILO documents to demonstrate three interlocking discursive schemas: development, paternalism, and colorblindness. While the DWA progressively shifts regulatory discourses, its conceptualiza- tion of work constitutes informality as a condition of deviancy. This positions informal workers, who often occupy other vulnerable intersectionalities, as outside the scope of contemporary so- cial protections. Gender, race, class, location and more factor into the formation of global and national labor policies; achieving equitable conditions for all workers requires grappling with the complexity of informality.