bluuebunny/crossref_metadata_2025 huggingface dataset:
Primary headaches and cognitive disorders — pathophysiologically associated and comorbidity conditions.
Authors: Iskra D. A. , Lobzin V. Yu. , Kalygin S. A.
Published: March 2019

Primary headaches (migraine, tension-type headache and other primary headaches) cause 3% of all disability cases in adult population, fully decrease possibilities of social functioning. Te phenomenon of the central sensitization is one of the fundamental pathophysiological units of primary headaches. NMDA receptors are involved both in initiation and in maintaining of mechanisms of a long-term central sensitization. NMDA activation by glutamate play important role in the initiation of primary headaches. Cognitive impairment development also conducted with NMDA-excitotoxicity due to hyper excitability of NMDA receptors. Tus, it is evident that mechanisms of antinociceptive changes in primary headaches and development of a glutamate excitotoxicity are strongly interdependent. Relationship between somatic symptoms, such as headache in dementia and cognitive symptoms now is represented more widely than just a comorbidity. Te gravity of migraine, tension-type headache and severity of cognitive impairment are strongly connected. Tus, the reliable interrelation between development of primary headache and cognitive decrease is traced, considering a community of pathophysiological mechanisms that has important practical value due to possible correction by NMDA-antagonists. Memantine not only slows the progression of cognitive symptoms in dementia, but also signifcantly inﬂuences the frequency and expressiveness of primary headache.
On the Foundation of the ”V. M. Bekhterev Friends’ International Society”
Authors: Neznanov N. G. , Akimenko M. A.
Published: March 2019

The article presents information  about the foundation of a new public organization,  the “V. M. Bekhterev Friends’ International Society”, at the V.M. Bekhterev National Research Medical Center for Psychiatry and Neurology with the aim to further extend the study of V.M. Bekhterev’s scientific legacy and to create, on the basis of the Society, the V. M. Bekhterev Encyclopedia.
Psychological diagnostic of risk factors for involving adolescents in the use of narcotic substances: the development of a methodical complex. Part 1. Scale structure and psychometric characteristics
Authors: Demenko E. G. , Rasskazova E. I. , Tkhostov A. Sh. , Brun E. A. , Arshinova B. V.
Published: March 2019

Paper  is  devoted  to  the  development  and  validation  of  the  methodological  complex  for psychological  diagnostic  of  the  risk  factors  for  involving  adolescents  in  the  use  of  narcotic  substances.  The diagnostic of people using psychoactive substances is difficult due to their defensive strategy of answers — both because  of  the  intentional  desire  to  keep  their  behavior  in  secret,  and  because  of  distortion  of  the  assessment of Self and own behavior. An expanded clinical-psychological observation, due to its high costs, is not always possible, which makes it urgent to develop a primary screening instruments, on the basis of which it is possible to identify risk groups for whom the clinical-psychological examination is especially important, controlling for possible falsifications in the responses. In this work three psychodiagnostic approaches are consistently applied to  overcome  these  difficulties:  after  the  initial  theoretical  development  of  constructs,  items  are  selected  based on  “empirical  keying”  approach  (by  their  ability  to  differentiate  the  clinical  and  control  groups),  and  then scales  are  refined  based  on  their  psychometric  characteristics  in  the  clinical  not  a  control  group.  This  first part of the paper presents the results of testing consistency and factor validity of the methodological complex scales conducted on a sample of 637 pupils of the upper grades of general education schools from 12 subjects of  the  Russian  Federation  and  108  pupils  involved  in  the  use  of  narcotic  substances.  The  methodological complex  includes  scales  of  technological  addictions,  antisocial  tendencies,  self-regulation,  emotional  control, novelty  seeking,  risky  behavior,  child-parent  relations,  coping  strategies  for  problem  solving,  social  support and  avoidance,  as  well  as  additional  indicators  of  socially  desirable  and  random  answers.
Single nucleotide polymorphism MTHFR677C>T and the severity of metabolic side effects of antipsychotics in patients with schizophrenia: the results of a pilot study
Authors: Kosataya M. A. , Marina A. V. , Sergeeva A. V. , Zhilyaeva T. V. , Blagonravova A. S. , Mazo G. E.
Published: March 2019

To predict the development of side effects and personalized selection of drug therapy, it seems relevant to study the association of individual genetic risk factors with undesirable side effects of antipsychotics in chronic patients with schizophrenia. Thereby the purpose of this study was to evaluate the association between the carriage of the T-allele of the single nucleotide genetic polymorphism MTHFR677C>T and the severity of the metabolic side effects of antipsychotics. As a result of the study a greater risk of developing components of the metabolic syndrome was revealed, as well as a significantly higher fasting blood glucose level in the group of carriers of the minor T-allele of polymorphism MTHFR677C>T.
Psychological diagnostic of risk factors for involving adolescents in the use of narcotic substances: the development of a methodical complex. Part 2. Criterion validity and analysis of profles
Authors: Demenko E. G. , Rasskazova E. I. , Tkhostov A. Sh. , Brun E. A. , Arshinova B. V.
Published: March 2019

Te second part of the paper presents the results of testing the criterion validity of the methodological complex scales conducted on a sample of 637 pupils of the upper grades of general education schools from 12 constituent entities of the Russian Federation and 108 pupils involved in the use of narcotic substances. Pupils using narcotic substances are characterized by a tendency to technological addictions, antisocial tendencies, difculties in self-regulation accompanied by overestimation of the own ability to control emotions, denying the interest for novelty, risky behavior and avoidance as well as difculties in child-parent relations. Some of these factors are manifested in those with a protective response strategy and others — in those with an open demonstration of difculties, which allows us to separate the two risk profles. In pupils appraising their ability to control emotions as high, the risk of involvement in the use of narcotic substances is associated with either a demonstrating or an illusory excessively «prosperous» profle: an overestimation of own emotional control and social support, denial of avoidance, denial of interest for novelty and risky behavior. In pupils appraising their ability to control emotions as low, the risk is higher in those with higher rates of technological addictions, antisocial tendencies, difculties in self-regulation and in child-parent relationships.
Neurovisualisation of the hippocampus: role in diadnostic of the early alzheimer disease
Authors: Neznanov N. G. , Ananyeva N. I. , Zalutskaya N. N. , Andreev E. V. , Akhmerova L. R. , Ezhova R. V. , Salomatina T. A. , Stulov I. K.
Published: March 2019

In our study we have analyzed MRI of mediobasal parts of temporal lobes in healthy volunteers and patients with Alzheimer disease in early stage based on medical literature and our experience. We have determined method of defnition and volume evaluation of diﬀerent hippocampal subfelds.
Clinical and neurophysiological features of mental disorders in patients with HIV infection
Authors: Neznanov N. G. , Khalezova N. B. , Hobeysh M. A. , Zakharova N. G. , Kissin M. Ya.
Published: March 2019

Summary.Te aim of the study was to study the clinical signifcance of changes in bioelectric activity for the purpose of identifying them as biological markers of mental disorders in patients with HIV infection. A cross-sectional study was conducted to diagnose mental disorders and search for neurophysiological markers in 62 patients with HIV infection at the St. Petersburg Center for the Prevention and Control of HIV and Infectious Diseases.

Results: 50% of patients with HIV infection without abuse disorders have mental disorders characterized mainly by adaptive reactions and mild cognitive impairment. Normal indicators of bioelectrical activity were determined in 16.1% of 62 patients. In the majority of patients (59.7%), bioelectrical activity was determined with a predominance of excitation in the medio-diﬀerent areas and a decrease in activity of the cerebral cortex. In 41.9% of patients, the processes of CNS excitation were increased in the form of an intensifcation of the reaction to photostimulation. Neurophysiological diﬀerences were revealed in patients with neurotic and stress-related disorders and organic changes in the CNS. For neurotic disorders in comparison with organic disorders, the EEG was normal or the disorganized type with predominance of alpha and beta activity were more likely, while in the case of organic disorders the desynchronous type of EEG was more ofen noted. Te development of psycho-organic syndrome in HIV patients is confrmed by deep restructuring of bioelectrical activity in the anterior parts of the brain.
Features of structural-morphological changes in cases of experimental intestinal antibiotic-induced dysbiosis
Authors: Bobyr V.V. , Poniatovskyi V.A. , Chobotar A.P. , Stechenko L.O. , Kryvosheyeva О.І. , Nazarchuk O.A. , Кovalenko О.О.
Published: March 2019

Nowadays, scientists often define dysbiosis as a condition of a microbial ecological system, in which there is a simultaneous abnormality of the functions and interaction mechanisms of its key components: macroorganism and indigenous microbiota associated with the mucous membranes of cavities and skin. At the same time, obviously, the basis of all these processes is changes of structural intestinal components that are caused by qualitative and quantitative changes in the normal microflora. Purpose: to study the ultrastructural organization of the mucous membrane of the small intestine of mice after the formation of dysbiosis of the intestine. Outbred white mice in the number of 40 units (20 - experimental and 20 control) was served as an experimental model. Antibacterial drugs (ampicillin, metronidazole and gentamicin) are used to form dysbiosis. The conducted experiments are allowed to establish that the using of antibacterial drugs in the above-mentioned doses contributes to shortening the length of the microvillus and their reduction (disappearance) in some places, destruction with subsequent disintegration. According to the results of electronograms analysis, the assumption was made about stimulating the secretory function of the small intestine enterocytes by powerful doses of antibacterial drugs. In addition, it was found that the formation of dysbiotic disorders is accompanied by a defect of the connection between epithelial cells due to the expansion of the intercellular space and the disappearance of the dense plate. Research results also indicate that antibiotics that were used in the experiment can cause development of apoptosis. In addition, it has been shown that, on the background of the dysbiotic disorders formation, the activation of immune processes is taking place, as evidenced by the appearance of a significant number of Paneth cells, plasma cells with enlarged tubules, apparently due to their filling with immunoglobulins, as well as the growth of numbers of luminalis eosinophils and basophils. The ability of antibiotics to form dysbiotic states with pronounced cytodestructive disorders in the epithelium of the small intestine with the development of apoptosis was substantiated; the argument about the immune stimulating effect of antibiotic induced dysbiosis is argued.
Novel Synthesis of 1,3,5-Trisubstituted 2-Pyrazolines Promoted by Chlorotrimethylsilane
Authors: Xie Zengyang , Bian Xiaoqin , Geng Xin , Li Shuangshuang , Wang Cunde
Published: March 2019

1,3,5-Trisubstituted-2-pyrazolines were effectively synthesised by utilising chlorotrimethylsilane as an efficient promoter in the cyclisation addition of phenylhydrazine to chalcones under nitrogen in acetonitrile. The clean, mild reaction conditions, high yields and a simple workup of target compounds were attractive features of the reaction which enables a facile preparative procedure for building the pyrazoline ring.
Microwave-Assisted Synthesis of 1,3,4-Thiadiazole Schiff Base Derivatives
Authors: Hu Jun , Sun Jianguang , Zhou Taoyu , Xu Yanhua
Published: March 2019

A rapid and efficient microwave-assisted synthesis method for the preparation of 1,3,4-thiadiazole Schiff base derivatives is described. These 1,3,4-thiadiazole Schiff bases (5a-h) were identified by IR, 1H NMR, elemental analyses. The target compounds were performed in a shorter reaction time compared with conventional heating methods.
KF/Al2O3 Promoted Aza-Michael Addition of 4-Aryl-7,7-Dimethyloctahydro-Quinazolinones to α, β-Ethylenic Compounds
Authors: Wang Xi-Cun , Wang Zhong-Jie , Zhang Zhang , Quan Zheng-Jun
Published: March 2019

The aza-Michael addition reaction of 4-aryl-7,7-dimethyl-1,2,3,4,5,6,7,8-octahydroquinazoline-2-one/thione-5-ones to α,β-ethylenic compounds in the presence of KF/Al2O3 furnishes N3-substituted quinazolinone derivatives. Those groups (NO2, MeO) with larger steric hindrance at the o-position of the phenyl ring of quinazolinone have an apparent affect on the chemical selectivity thus giving the N1-subsituted products.
Efficient Synthesis of Novel Chiral Bisimidazolium Dichlorides under Solvent-Free Conditions
Authors: Zhang Lingqiao , Yang Long , He Pan , Guan Pei , Shi Yanhui , Pang Guangsheng , Cao Changsheng
Published: March 2019

A series of novel chiral bisimidazolium and chiral bis(benzimidazolium) dichlorides with different substituents were synthesised effectively from the corresponding N-substituted imidazoles or N-substituted benzimidazoles with chiral (S)-2,2'-bis(2-chloroethoxy)-1,1'-binaphthalene in solvent-free conditions at ambient pressure. This protocol features a short reaction time, good yields, an eco-friendly process and easily control and handling. These compounds were fully characterised by NMR, IR and elemental analysis, and their specific rotations were given.
Fluorescent Recognition of Pyrophosphate in Water by a New Chemosensing ensemble
Authors: Tang Lijun , Liu Minghui
Published: March 2019

A new chemosensing ensemble that exhibits sensitive and selective recognition of pyrophosphate in 100% aqueous solution at physiological pH has been developed. The chemosensing ensemble was constructed by a dinuclear Zn(II) complex and eosin Y, the receptor–indicator pair is capable of selectively discriminating pyrophosphate from other common anions such as I-, Cl-, Br-, F-, CH3COO-, HSO4-, NO3-, H2PO4-, HPO42-, PO43- and NCS- in water at pH 7.4.
PENERAPAN TEMA PANOPTICON ARCHITECTURE DALAM MERANCANG LEMBAGA PEMASYARAKATAN KELAS IIA SIMALUNGUN
Authors: Aulia Dwira Nirfalini , BR Perangin-Angin Cynthia Adelina
Published: March 2019

Abstract: Pematang Raya is the new capital city of Simalungun Regency, North Sumatera, Indonesia which used to be seated in Pematangsiantar. This capital city was formed on June 23rd, 2008 and some of the government institutions of Simalungun Regency have already been seated at Pematang Raya. As an example, The Regency Police of Simalungun and the District Military Command of Simalungun, which are one of the legal institutions, have already been seated at Pematang Raya while the District Court IB of Simalungun and the District Attorney of Simalungun are still seated at Pematangsiantar. JR Saragih, who is the regent of Simalungun Regency, is eager to move the seat of the District Court IB of Simalungun and the District Attorney of Simalungun to Pematang Raya. Simalungun Regency does not have any penitentiary until this day. That is why the inmates who get terms at the District Court IB of Simalungun are sent to Pematangsiantar Penitentiary. Researchers identify the need of Simalungun Regency to increase the strength of the legal institutions in Simalungun Regency by designing a penitentiary. As an addition, the penitentiaries in Indonesia are getting worse time by time. Analysis and concepts of this design are using the interpretation of Panopticon Architecture which emphasizes a maximum supervision to the penitentiary.Keywords: Simalungun, Panopticon Architecture, PenitentiaryAbstrak: Pematang Raya merupakan Ibukota baru Kabupaten Simalungun, Sumatera Utara, Indonesia yang dulunya adalah Pematangsiantar. Pematang Raya dibentuk pada tanggal 23 Juni 2008 dan beberapa institusi kepemerintahannya sudah berkedudukan di Pematang Raya. Sebagai contoh, Polres Simalungun dan KODIM Simalungun merupakan salah satu dari instansi hukum Kabupaten Simalungun yang sudah berkedudukan di Pematang Raya, sedangkan Pengadilan Negeri Kelas IB Simalungun dan Kejaksaan Negeri Simalungun masih berkedudukan di Pematangsiantar sampai saat ini. Bupati Kabupaten Simalungun, JR Saragih, berkeinginan untuk memindahkan Pengadilan Negeri Kelas IB Simalungun dan Kejaksaan Negeri Simalungun dari Pematangsiantar ke Pematang Raya agar terciptanya instansi hukum yang kuat di Kabupaten Simalungun, Sampai saat ini, Kabupaten Simalungun tidak memiliki UPT Pemasyarakatan. WBP yang mendapat vonis hukum di Pengadilan Negeri Kelas IB Simalungun dititipkan ke Lembaga Pemasyarakatan Kelas IIA Pematangsiantar. Penulis mengidentifikasi kebutuhan Kabupaten Simalungun untuk meningkatkan kuatnya institusi hukumnya dengan merancang sebuah Lembaga Pemasyarakatan. Ditambah lagi, keadaan Pemasyarakatan di Indonesia kian memburuk. Dengan demikian, penulis menggunakan interpretasi tema Panopticon Architecture dalam analisis dan konsep rancangan yang menekankan kepada pengawasan yang maksimal di Lembaga Pemasyarakatan.Kata Kunci: Simalungun, Panopticon Architecture, Lembaga Pemasyarakatan
Clinical improvement with intensive robot-assisted arm training in chronic stroke is unchanged by supplementary tDCS
Authors: Edwards Dylan J. , Cortes Mar , Rykman-Peltz Avrielle , Chang Johanna , Elder Jessica , Thickbroom Gary , Mariman Juan J. , Gerber Linda M. , Oromendia Clara , Krebs Hermano I , Fregni Felipe , Volpe Bruce T. , Pascual-Leone Alvaro
Published: March 2019

Background:

Intensive robot-assisted arm training in the chronic phase of stroke recovery can lead to clinical improvement. Combinatorial therapeutic approaches are sought to further optimize stroke recovery. Transcranial direct current stimulation (tDCS) is one candidate to combine with robotic training, as transient increases in excitability and improvements in motor behavior have separately been reported.

Objective:

To determine whether tDCS, delivered prior to robotic training, could augment clinical improvement.

Methods:

We conducted a dual-site, randomized controlled trial in 82 chronic ischemic stroke patients (inclusion > 6 m post-injury, dominant hemisphere, first stroke; residual hemiparesis) who were split into two groups to receive tDCS (M1-SO montage, anode ipsilesional, 5×7 cm electrodes, 2 mA, 20 mins) or sham tDCS, prior to robotic upper-limb training (12 weeks; 36 sessions; shoulder-elbow robot or wrist robot on alternating sessions). The primary end-point was taken after 12 weeks of training, and assessed with the Upper Extremity Fugl-Meyer impairment scale (FM). Corticomotor conduction was assessed with transcranial magnetic stimulation (TMS).

Results:

For the combined group ( n = 82; post-training) robotic training increased the FM by 7.36 points compared to baseline ( p < 0.0001). There was no difference in the FM increase between the tDCS and sham groups (6.97 and 7.73 respectively, p = 0.46). In both groups, clinically meaningful improvement (≥5 points) from baseline was evident in the majority of patients (56/77), was sustained six months later (54/72), and could be attained in severe, moderate and mild baseline hemiparesis. Clinical improvement was associated with increased excitability in the affected hemisphere as assessed by resting motor threshold (pre-post p = 0.029; pre-post 6 months p = 0.029), but not with threshold-adjusted assessment of MEP amplitude (pre-post p = 0.09; pre-post 6 months p = 0.15). Participants with motor evoked potentials were more likely to improve clinically than those without (17/18, 94%, versus 39/59, 66%, p = 0.018).

Conclusions:

Our study confirms the benefit of intensive robot-assisted training in stroke recovery, and indicates that conventional tDCS does not confer further advantage to robotic training. We also showed that corticospinal integrity, as assessed by TMS, is a predictor of clinically meaningful response to intensive arm therapy in chronic stroke.
Factors affecting the success in business of small and medium enterprises in Ho Chi Minh City
Authors: Van Thich Nguyen
Published: March 2019

This research aims to identify the factors affecting the success of small and medium enterprises (SMEs) in Ho Chi Minh city. It helps to reduce the risk of failure and increase the chances of success for the business. The study examined seven factors affecting the success of SMEs in Ho Chi Minh city. These factors include: technology resources, management skills, products and services, marketing strategies, ways of business and collaboration, financial resources, and the external environment. The theoretical framework has been drawn up and the questionnaire has been designed based on the selected elements. Seven hypotheses have been developed to identify the factors that influence the business success of small and medium enterprises in Ho Chi Minh city. All hypotheses have been successfully tested and accepted with MINITAB software. The results of the regression analysis show that technological resources, management skills, products and services, marketing strategies, ways of business and cooperation, financial resources and external environment exist have significant positive impacts on the success of SMEs in Ho Chi Minh city.
ESTIMATION OF SATELLITE ALTIMETER ECHO-SIGNAL PARAMETERS BY STATISTICAL FITTING METHODS IN THE COURSE OF RETRACKING
Authors: Borovitsky D. S. , Zhesterev A. E. , Ipatov V. P. , Mamchur R. M.
Published: March 2019

Satellite radar altimeters play a key role in numerous space missions for the remote Earth sensing. The data they provide are used in solving various fundamental and applied problems of geophysics, oceanography, meteorology, etc. In many modern measuring systems the altimeter data is processed in several stages. One of them is the ground-based retracking of the information streamed from the spacecraft. The goal of this work is to study altimeter parameter estimators in the course of the satellite altimeter data retracking by ground-based complex. The main task of delay-lock loop onboard a satellite carrier is a reliable keeping of received echo-signal within the tracking window. More accurate estimates of information parameters are worked out by the ground segment where data from the satellite is delivered via telemetry. Retracking can be performed either without using any physical echo model, or relying on some mechanism under generation of response of an illuminated surface to the probing signal. In the latter case, the measuring results become more trustworthy. The paper deliberations are based on the model close to the classical Brown’s one, they include algorithms of its parameters statistical fitting to the observation and computer simulation of fitting according to the maximal likelihood (ML) and the least squares (LS) methods. The results obtained are compared to the potential attainable and show that while LS fitting yields noticeably to the potential, experimental accuracy of ML-fitting practically coincides with the potential one.
Higher education administrators’ response to student activism and protests
Authors: Mahler-Rogers Dionicia
Published: March 2019

This study examines college and university leaders’ responses to student activism and protest on U.S. college campuses between Fall 2014 to Summer 2016. using a phenomenological research tradition. The results revealed that while different types of institutional brands benefit from activism, the difference seemed to be realized in the resources the institution allocates to support and foster activism and inclusion. The views of constituencies revealed varying ideas and opinions, but the best leaders will navigate the path that enables tough decisions without alienating key players who are critical to the success of the efforts.
Alternative Methods of Solving Biasedness in Chi – Square Contingency Table
Authors: Charles C. Okeke
Published: March 2019

Some methods of solving the biasedness in Chi–square Contingency table statistic were considered. Phi Coefficient, Contingency Coefficient and Cramer’s V tools were employed to solve the biasedness in the use of Chi–square test. Our results show that any of Phi coefficient, Contingency coefficient or Cramer’s V can be used to describe the association between two variables if the data matrix is 2 x 2. Contingency Coefficient was recommended as a good statistic when the matrix dimension is the same while the Cramer’s V is most adequate when the data matrix differs.
Investigating Factors Influencing Brain Drain of Citizens of Azad Kashmir Pakistan
Authors: Ali Ghulam Wajahat , Ali Waqas , Ali Shujahat , Masood Khan Muhammad , Ali Khan Raja Nasir , Farooq Muhammad
Published: March 2019

The primary purpose of the paper to analyze the impact of Human Capital Migration on the social sector of Azad Jammu & Kashmir. Population of the study was the above matriculation (10th grade) migrants shifted from Pakistan to abroad. A sample of 300 people was request to fill the questionnaire out of which data collected from the 225 participants. To strengthen the study, we utilized both primary as well as secondary sources for data collection. Regression and correlation statistics utilized to identify the association between the predictor and outcome variables. Conclusively, there are numerous root causes of the Educated Human Capital Migration from the Mirpur Division Azad Jammu & Kashmir. This study finds that the Economic Factor, Social Factor, Job Opportunity Factor, Political Factor, Education System Factor, Pure Science Factor, Technological Factor has a significant impact on the phenomenon of Brain Drain. In the long run the migration of Educated Human Capital destructs the institution as well as the region. Study is benificial for the policy makers of Azad Jummu and Kashmir to attract the skilled migrants back to their orgin. The acamdicians can further study thus topic to explore the Brain Drain at demographic level.
Las familias rurales, sujetos colectivos de derechos : el caso de Guayabal de Síquima.
Authors: Bueno Ana Marcela , Torres G. Myriam Fernanda
Published: March 2019

El presente artículo documenta las dinámicas socio familiares en Guayabal de Síquima a partir de su abordaje como sujeto colectivo de derechos, reconociendo sus relaciones cotidianas, condiciones socio económicas y culturales, además de dar cuenta de la vivencia de la participación como una concienciación respecto a la reivindicación de sus derechos en un ámbito tradicional como el contexto rural. Lo anterior se realizó a partir de un estudio cualitativo recolectando información a través de una encuesta inicial y su complementación con entrevistas y talleres, con la participación de padres, madres, niños y niñas, quienes desde sus experiencias expresaron vivencias referidas a sus derechos como colectivos familiares. Para comprender sus discursos fue necesario dar cuenta de algunos elementos conceptuales que son retomados en el desarrollo de los hallazgos. Como conclusión general se establece que identificar esta condición de las familias, favorece la sociedad que se viene construyendo hacia la paz, la cual requiere de sujetos empoderados de sus derechos y por ende conscientes de sus posibilidades como sujetos y colectivos en el ejercicio de su ciudadanía.
La cobertura educativa en escuelas públicas del departamento de Bolívar (Colombia) : un análisis de eficiencia y productividad.
Authors: Maza Avila Francisco , Batista Ochoa Iván , Vergara Schmalbach Juan Carlos
Published: March 2019

Este artículo analiza la eficiencia y la productividad en la cobertura de las escuelas públicas de 44 municipios del departamento de Bolívar, Colombia, para el periodo 2011-2013, empleando para ello el Análisis Envolvente de Datos y el Índice de Productividad de Malmquist, a partir de la información suministrada por el Ministerio de Educación Nacional de Colombia y la Secretaria de Educación del departamento de Bolívar, relacionada con el número de estudiantes matriculados, número de docentes, inversión y los metros cuadrados por establecimiento educativo. Los resultados indican una desmejora de la eficiencia técnica de todos los establecimientos educativos en el periodo de análisis. Con respecto a la productividad, se observa una disminución durante el periodo considerado, pese a la evolución positiva de la tecnología. Se pude concluir, que los municipios no están utilizando de forma eficiente y productiva los recursos públicos destinados para mejorar la cobertura educativa.
HUBUNGAN PENERAPAN PROSES KEPERAWATAN IDA JEAN ORLANDO TERHADAP PENINGKATAN KUALITAS PELAYANAN DI RUANG PERAWATAN KRITIS IGD DAN ICU RSUD KABUPATEN PANGKAJENE DAN KEPULAUAN
Authors: Zainal Amanah Restuyana , Ake Julianus , Pasinringi Syahrir
Published: March 2019

Perawat sebagai salah satu tenaga kesehatan di rumah sakit memegang peranan penting dalam upaya mencapai tujuan pembangunan kesehatan. Keberhasilan pelayanan kesehatan bergantung pada partisipasi perawat dalam memberikan asuhan keperawatan yang berkualitas bagi pasien, agar dapat mewujudkan pelayanan yang berkualitas dan berkinerja tinggi diperlukan tenaga keperawatan yang profesional, memiliki kemampuan intelektual, teknikal interpersonal, bekerja berdasarkan standar praktik, serta memperhatikan kaidah etik dan moral. Salah satu model penerapan asuhan keperawatan yang terbaik adalah memberikan respon segera terhadap pasien, ini dapat meningkatkan kualitas pelayanan keperawatan melalui penilaian kepuasan pasien terhadap perawat sebagai salah satu indikator mutu pelayanan. Tujuan penelitian ini adalah untuk mengetahui hubungan penerapan proses keperawatan Ida Jean Orlando dengan peningkatan kualitas pelayanan di Ruang Perawatan Kritis IGD dan ICU RSUD Kabupaten Pangkajene dan Kepulauan.Desain penelitian ini menggunakan metodeCross Sectional, metode sampling yang digunakan adalah Purposive Sampling. Sampel sejumlah 56 perawat dan 129 pasien yang memenuhi kriteria inklusi. Variabel yang diteliti adalah variabel independent yaitu proses keperawatan : tanggung jawab perawat, mengenal perilaku pasien, reaksi segera, disiplin dalam keperawatan dan evaluasi kemajuan kondisi pasien, variabel dependent yaitu kepuasan pasien. Data dikumpulkan menggunakan kuesioner dan dianalisis dengan menggunakan uji statistik Korelasi Regresi Linear dengan tingkat kemaknaan 0.05. Hasil penelitian menunjukkan bahwa perawat dalam melaksanakan tanggung jawab dengan cukup baik sebesar 87.60%, , perawat mengenal perilaku dengan baik sebesar 68.99%, perawat yang memberikan reaksi segera dengan baik sebanyak 56.59%, perawat telah melaksanakan disiplin dalam asuhan keperawatan dengan baik sebesar 56.59%, dan perawat yang mengevaluasi kemajuan kondisi pasien dengan baik sebesar 90.70%. Data kepuasan pasien sebesar 75.81% berdasarkan perhitungan Indeks Kepuasan Masyarakat dengan mutu pelayanan keperawatan dinilai baik. Hasil uji statistik regresi linear, menunjukkan nilai sig.p=0.000 (p<0.05), sehingga H1 diterima karena terdapat hubungan yang positif dan signifikan antara proses keperawatan Orlando dengan kepuasan pasien di ruang perawatan kritis RSUD Kabupaten Pangkajene dan Kepulauan. Dari hasil penelitian ini, RSUD Kabupaten Pangkajene dan Kepulauan dapat lebih meningkatkan kualitas pelayanan dengan lebih meningkatkan pelayanan keperawatan di ruang perawatan kritis atau di ruang pelayanan lainnya dengan menitikberatkan pada proses keperawatan segera.

Kata kunci : Proses Keperawatan Orlando, Kepuasan Pasien, Ruang Perawatan Kritis IGD dan ICU
PENGARUH PURSED LIP BREATHING DAN MENIUP BALON TERHADAP KEKUATAN OTOT PERNAPASAN, SATURASI OKSIGEN DAN RESPIRATORY RATE PADA PASIEN PPOK
Authors: Junaidin Junaidin , Syam Yuliana , Irwan Andi Masyitha
Published: March 2019

Masalah : Penyakit Paru Obstruksi Kronik (PPOK) merupakan sejumlah gangguan yang mempengaruhi pergerakan udara dari dan keluar paru. Hal ini disebabkan karena terjadinya kelemahan otot pernapasan dan obstruksi, sehingga terjadi peningkatan resistensi aliran udara, hiperinflasi pulmoner dan ketidakseimbangan ventilasi dan perfusi yang dapat menyebabkan penurunan kadar saturasi oksigen. Terdapat beberapa penanganan pada pasien PPOK salah satunya penanganan secara non farmakologis (program latihan) salah satunya program rehabilitasi, program ini terdiri dari pursed lip brething meniup balon.

Tujuan : untuk mengetahui pengaruh latihan pursed lip breathing dan meniup balon terhadap peningkatan kekuatan otot pernapasan, respiratory rate dan peningkatan saturasi oksigen pada pasien penyakit paru obstruksi kronis.

Metode : Database yang digunakan dalam pembuatan literatur review ini adalah PubMed, Google Scholar, Proquest, Science direct dan Wiley.

Hasil : Terdapat 112 artikel yang diidentifikasi dan dipublikasikan dari tahun 2012-2018. Dari 109 artikel 7 artikel yang memenuhi kriteria inklusi. Beberapa hasil penelitian menunjukkan bahwa pursed lip breathing dapat memperbaiki kekuatan otot pernapasan, saturasi oksigen dan menurunkan frekuensi pernapasan, begitu pula dengan meniup balon.

Kesimpulan : Untuk menghindari  gangguan vital  pada pasien PPOK akibat terganggunya ventilasi pada pasien PPOK dapat pula dilakukan dengan program latihan, salah satunya yaitu dengan cara rehabilitasi yang terdiri atas pursed lip breathing dan meniup balon hal ini dapat meningkatkan kekuatan otot pernapasan, saturasi oksigen dan menurunkan frekuensi pernapasan.

Kata Kunci : Pursed lip breathing, meniup balon, otot pernapasan, saturasi oksigen, respiratory rate
TINGKAT STRES DENGAN PENINGKATAN KADAR GULA DARAH PENDERITA DIABETES MELLITUS
Authors: Bistara Difran Nobel , Zahroh Chilyatiz , Wardani Erika Martining
Published: March 2019

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ABSTRAK

Diabetes Mellitus merupakan salah satu penyakit kronik yang memerlukan waktu perawatan lama, pembiayaan perawatan yang sangat mahal, selain itu prevalansi diabetes milletus juga meningkat. Keharusan penderita diabetes mellitus dalam mengubah pola hidupnya agar gula darah dalam tubuh tetap seimbang dapat mengakibatkan mereka rentan terhadap stress. Stress pada penderita diabetes mellitus dapat mengakibatkan gangguan pada pengontrolan kadar gula darah. Tujuan penelitian untuk mengetahui adanya hubungan tingkat stress dengan kadar gula darah pada penderita Diabetes Mellitus. Penelitian ini menggunakan metode analitik observasional dengan pendekatan cross sectional dengan sampel berjumlah 45 responden penderita Diabetes Melitus di wilayah RW 7 Kelurahan Simokerto Kecamatan Simkerto Surabaya yang diambil dengan teknik simple random sampling. Pengukuran tingkat stress menggunakan kuesionar. Kadar gula darah diperoleh dari observasi menggunakan glucometer secara acak. Data dianalisis dengan menggunakan uji korelasi spearman rank. Hasil uji korelasi spearman rank didapatkan nilai p=0,00 dan r=0,909. Hal ini semakin tinggi tingkat stress yang dialami akan semakin tinggi pula nilai kadar gula darah. Saran untuk peniliti selanjutnya adalah dapat meniliti factor lain yang dapat mempengaruhi kadar gula darah, serta untuk melakukan observasi perilaku stress agar hasil lebih valid.
HUBUNGAN SIKAP TENTANG HIPERTENSI DENGAN FREKUENSI KEKAMBUHAN HIPERTENSI PADA PENDERITA HIPERTENSI DI RW 06 KARAH KECAMATAN JAMBANGAN SURABAYA
Authors: Ainiyah Nur , Wijayanti Lono
Published: March 2019

Kekambuhan pada penderita hipertensi sering terjadi selama hidupnya. Kekambuhan tersebut merupakan dampak dari faktor sikap yang tidak dapat dihindari oleh individu, antara lain ketidak adequatan dalam menghadapi stress, beban kerja yang cukup tinggi., gaya hidup yang tidak sehat,  dan konsumsi makanna yng tidak sehat. Prevalensi di kejadian hipertensi di perkotaan 39,9%  (37,0%-45,8%) dan di pedesaan 44,1%  (36,2%-51,7%). Kenyataan yang ada di masyarakat menunjukkan tingginya prevalensi penderita hipertensi, dimana dari data di Posyandu Lansia di Karah meningkat tiap bulannya.

Metode dalam penelitian ini adalah deskriptif analitik  dengan menggunakan tehnik sampling yaitu accidental sampling sejumlah 24 orang yang menderita hipertensi di RW 06 Kelurahan Karah Kecamatan Jambangan Variabel dalam penelitian ini adalah sikap tentang hipertensi dan frekuensi kekambuhan. Pengumpulan data menggunakan kuesioner. Analisa data yang digunakan  uji statististik lambda.

Berdasarkan hasil perhitungan statistik uji (lambda) didapatkan nilai probabilitas (p) sebesar 0.000 lebih kecil dari α (0.05) maka Ho ditolak dan Ha diterima yang menunjukan adanya hubungan yang signifikan antara sikap tentang hipertensi dengan frekwensi kekambuhan pada penderita hipertensi di RW 06 Karah Kecamatan Jambangan Surabaya., selain itu juga didaptkan nilai besarnya korelasi 0.467 yang menunjukkan bahwa kekuatan korelasinya sedang.

Penerapan sikap yang favorable (mendukung) sebagai salah satu alternative cara yang dapat dilakukan oleh penderita hipertensi untuk meminimalkan frekuensi kekambuhan hipertensi, melalui pengaturan dan modifikasi diit pada penderita hipertensi serta perlu adanya penyuluhan tentang hipertensi tersebut yang dilakukan secara berkesinambungan oleh tenaga kesehatan.

Kata Kunci : sikap, frekuensi kekambuhan, hipertensi
Preparation and Analysis of Polar Hawthorn Berry Extracts, Industrial Application in Poultry Processing
Authors: Kubovics Márta , Al-Hamimi Said , Huszár György , Komka Kinga , Turner Charlotta , Székely Edit
Published: March 2019

For years, it is an actuality in the poultry processing industry, that the body and the cardiovascular system of the chickens are not strong enough due to the shortened rearing time. This induces, that the quality of the chicken breast is not appropriate for selling, since during the processing procedure, frequently blood spots appear inside the meat. These damaged parts need to be removed, causing huge economic loss. In this paper a solution for this problem is searched using hawthorn, a traditional herb, with well-known beneficial effects to the cardiovascular system. Improvement of the product quality and the reducing amount of the removed meat are supposed by applying a treatment with a polyphenol-rich drinking tincture made from the plant. Beside the preparation of the drinking liquid, including pretreatment, extraction and dilution steps, chemical analysis of the phenolic compounds is also conducted. The result of the drinking test shows that the extent of the blood spots, and thus the quantity of the "cut off" meat decreased significantly, however the reduction of the meat weight and a slight change in the death rate are also needed to take into consideration. It has been found, that the total phenolic contents of the berry are similar to literature data, while they show moderate antioxidant efficiency. Several phenolic acids, procyanidins and flavonoids were identified as the main phenol compounds of the applied extract.
A Metal-organic Framework with Paddle-wheel Zn2(CO2)4 Secondary Building Units and Cubane-1,4-dicarboxylic Acid Linkers
Authors: Földes Dávid , Kováts Éva , Bortel Gábor , Jakab Emma , Pekker Sándor
Published: March 2019

A new crystal structure of catena-(bis((µ4-cubane-1,4-dicarboxylato)-(N-methyl-2-pyrrolidone)-zinc(II)) N-methyl-2-pyrrolidone solvate) (1) was prepared by solvothermal method. The crystal structure of the compound was analyzed by single-crystal X-ray diffraction. It has a P1 space group, with lattice parameters a = 10.7190(4) Å, b = 10.8245(5) Å, c = 10.8403(8) Å, α = 80.291(5)°, β = 70.0015(5)°, γ = 77.531(4)°, V = 1147.97(12) Å3. The secondary building units of 1 consist of 2 central Zn ions, coordinated by 4 carboxylate groups in a bis-monodentate way, forming a square planar configuration of Zn2(CO2)4, known as paddle-wheel units. The paddle-wheels are connected by cubane-1,4-dicarboxylic acid linkers at the edges, resulting in a two-dimensional coordination polymer with a square lattice (sql) underlying network topology. The axial sites of the zinc atoms are occupied by N-methyl-2-pyrrolidone molecules. In this new crystal structure the two-dimensional polymer planes are interstacked by weak dispersion bonds. The axial N-methyl-2-pyrrolidone solvent molecules determine the distances of planar polymer planes. The thermal properties of this new structure were studied by thermogravimetry/mass spectrometry in inert atmosphere. It was found, that the organic linkers in the framework structure do not decompose below 200 °C. The stochiometry of the activated compound is Zn2[C8H6(COO)2]2(C5H9NO)2, as determined by thermogravimetry in oxidative atmosphere.
Sistem Keamanan Data Text Dengan Data Encryption Standard (DES) Dan Metode Least Significant Bit (LSB)
Authors: Pratistha Indra , Prakoso Paholo Iman
Published: March 2019

Current information can be delivered quickly without knowing the geographical boundaries using the internet. However, the information transmitted can be intercepted by the middle of the road which is not desired, then the security of the data actually becomes a very important issue. The development of computer systems and networks and the interconnection through the Internet has increased, of course, require data security and reliable message in order to avoid the attack. To secure internet data or message network necessary cryptographic encryption methods, one method of data encryption that there is a method of data encryption standard (DES) and subsequently inserted into the Lakeside digital images (steganography) using the method of least significant bit (LSB).
LENGTH OF EMPLOYMENT AS A RISK FACTOR FOR HEALTH PROBLEMS IN MINERS OF THE KOLA POLAR REGION
Authors: Syurin S A , Skripal B A , Nikanov A N
Published: March 2019

It is known that an increase in the exposure duration of occupational hazards associated with the extraction of ore raw materials negatively influences miners' health. The purpose was to study the peculiarities of employment length influence on the health disorders formation in 1558 underground apatite miners in the Kola Polar region. It was found that length of employment which exceeded 3 years was a significant risk factor for health problems in apatite miners in the Kola Polar region. Comparison of different five-year employment periods (
MEDICAL AND ECOLOGICAL ASPECTS OF ASSOCIATIONS BETWEEN HUMAN EXPOSURE TO TRACE CONCENTRATIONS OF STABLE BARIUM AND STRONTIUM AND FUNCTIONAL DISORDERS OF THE BODY. A REVIEW
Authors: Chashchin V P , Ivanova O M , Ivanova M A
Published: March 2019

A systematic analysis of the published results of studies on the effect of trace elements such as barium (Ba) and strontium (Sr) on functional systems of the human body. With sufficient intake of stable Sr isotopes, a decrease in pulse arterial pressure is observed in the morning, associated with a decrease in mortality among patients with ischemic heart disease and arterial hypertension. There is a statistically significant linear relationship between the ratio of the Ba and Sr content in the hair and the circadian heart rate index, that is associated with an increase in the incidence of thrombosis, particularly during treatment with the Strontium ranelate at therapeutic doses. A statistically significant negative correlation was found between the Ba tissue concentrations and the increase in the patient's age that is also associated with an increase in the risk of progressive degenerative brain disorders, as well as chronic obstructive pulmonary disease. The possible association of Sr and Ba tissue concentrations in the body with the risk of Kashin-Beck disease is discussed. For early detection of this disease in the population residing endemic areas and the areas of its sporadic cases, it is advisable to evaluate the function of active flexion of the distal joints of II - IV fingers of the hands in people aged 4 to 26 years with imaging the bone structure of these fingers in the people at risk within acceptable doses of radiation.
MEDIA SOSIAL SEBAGAI STRATEGI PENGEMBANGAN LAYANAN PERPUSTAKAAN
Authors: Rumani Sri
Published: March 2019

Social media has a positive side that can be utilized for the development of library services that orientated for the benefit of the user. Excellent service based on information and communication technology becomes a challenge for librarian as library driving machine. Therefore librarians must create innovation and creativity outside the comfort zone. The thought of out of the box in the corridor of librarianship is a must for librarians so that the information rights of the librarian can be fulfilled. This paper has the urgency of order advance in information and communication technology can be utilized by the librarians who manage the library, for the benefit of the user. As for the purpose is the librarian can utilize social media to improve the prime service oriented for the interest of the user. The research method used literature study is a series of activities related to library data collection methods, reading and recording and processing library materials. The result of social media Facebook for extension service is significant that the service extension through Facebook has benefits for the user, besides fast, easy, cheap, without having to come to the library and avoid penalty sanction.
MENGAMBIL MANFAAT MEDIA SOSIAL DALAM PENGEMBANGAN LAYANAN
Authors: Widada Cahyana Kumbul
Published: March 2019

Information technology has brought changes in all aspects of life in today's modern world. The Internet is becoming more popular and familiar as a source of information. Social media is a medium on the internet that allows users to represent themselves as well as interact, cooperate, share, communicate with other users and form a virtual social bond. The type of social media with all its characteristics brings a positive influence in building the service model. In research at Library of Muhammadiyah University of Surakarta (UMS) the users of social media Facebook (29%), Youtube (22%), Instagram (21%), Twitter (17%), Blog (7%), and wiki (4%). Facebook is the most popular of social media, allowing it to be developed as a means of meeting and online discussions that interact with each other.
PERAN TERAS BACA GUYUB RUKUN DALAM MEMBERDAYAKAN MASYARAKAT DUSUN JAMBON
Authors: Kurniawan Eko , Setyowati Risha , Gandarizki Muh. Nur Dear
Published: March 2019

Nowadays, there are many types of libraries that are developing, one of which is the community library or commonly called the Taman Baca Masyarakat (TBM). TBM is a library located around the community aims to increase reading interest to the surrounding community. TBM located in Jambon RT 29 Argosari Sedayu village Bantul, DIY is named with Teras Baca Guyub Rukun. TBM was established since 2015 until now have programs that are able to empower the surrounding community. This article was prepared using a qualitative descriptive method, in order to be explained in detail about how the role of TBM Teras Baca Guyub Rukun in empowering the community of Jambon. The purpose of this article is to inspire other libraries from the activities which are conducted by TBM Teras Baca Guyub Rukun, thereby the community can develop economically and educationally. The conclusion of this article is that the people of Jambon village get many advantages from the presence of TBM. Starting from the children began to read, the number of plants grown by children and teenagers, the youth who began to increase their creativity in growing entrepreneurial spirit, the mother of PKK and girls who began to cook, teenagers who have dared to appear in public, and the number of teenage activities as inspired by TBM by conducted garbage bank.