bluuebunny/crossref_metadata_2025 huggingface dataset:
Repetitive Transcranial Magnetic Stimulation in Delirium: A Double-blind, Randomized, Sham-controlled, Pilot Study
Authors:   Department of Psychiatry, School of Medicine, Iran University of Medical Sciences, Tehran, Iran., Yaghoubi Emad , Shariat Seyed Vahid ,   Mental Health Research Center, Iran University of Medical Sciences, Tehran, Iran., Rashedi Vahid ,   School of Behavioral Sciences and Mental Health (Tehran Institute of Psychiatry), Iran University of Medical Sciences, Tehran, Iran., Ghanbari Jolfaei Atefeh ,   Mental Health Research Center, Iran University of Medical Sciences, Tehran, Iran.
Published: June 2022

Introduction: Delirium is a fatal but potentially reversible disorder of the central nervous system that imposes high costs on health systems. This study aims to evaluate the effect of intermittent theta-burst stimulation on the severity and course of delirium disorder. Methods: This is a double-blind, randomized, sham-controlled pilot study. The study participants were randomly allocated into the active (active intermittent theta-burst stimulation) and sham groups. The severity of delirium was assessed 15 minutes before the intervention and 15 minutes after that by the Neelon and Champagne (NEECHAM) confusion scale. Results: In the active group, total and subscale scores of NEECHAM significantly decreased after intervention (P<0.05). Although no statistical difference was found in the control group regarding the subscale scores of NEECHAM, the difference in the total scores before and after the sham intervention was statistically significant. Conclusion: Carrying one session of repetitive transcranial magnetic stimulation on the left dorsolateral prefrontal cortex can reduce the delirium severity in a short period, although it will not decrease the number of delirium cases three days after the intervention.
İbrâhim (a.s) ve Ailesinin Urfa ile Olan Bağlantısı
Authors: GÜNDÜZ Ahmet
Published: June 2022

Urfa’nın dinî anlamda en kabul görmüş niteliği “Peygamberler Şehri” oluşudur. Peygamberler içerisinde kendisiyle en fazla özdeşleştirildiği peygamber ise Hz. İbrâhim’dir. Urfa bölgesinin Hz. İbrâhim’in (a.s.) ailesi özelindeki bağlantısının ilmî verilere dayalı olarak ortaya konması büyük önem arz etmektedir. Böyle bir çalışma halk arasındaki inanışın ve seyyahların notlarında yer alan bilgilerin ne denli doğru olduğunu da ortaya çıkacaktır.

Kur’an’da Hz. İbrâhim’in ailesi bağlamında Urfa bölgesine dair açık bir isim geçmemektedir. Ancak Tevrat ve İncil’de bazı ayrıntılar yer almaktadır. Bu bilgiler arkeolojik veriler, tarihî bilgiler ve ilmî disiplinler göz önüne alınarak yorumlandığında konu açığa kavuşmaktadır. Buna göre Hz. İbrâhim’in ve ailesinin Urfa, Harran, Suruç ve eskiden Harran’a bağlı olan ‘Aynu’l-‘Arûs arasında son derece yakın bir ilişkisi vardır. Babası, amcaları ve dayıları bu bölgede yaşamıştır. Hz. İbrâhim’in doğumu, ateşe atılması ve ilk evliliği buralarda olmuş, hicreti de bu bölgeden başlamıştır. Oğlu İshâk ve torunu Ya‘kûb’un bölge ile bağı sıhriyet yoluyla devam etmiştir.
Modernleşme Sürecinde Tasavvuf ve Günümüzde Tasavvuf Kültürünün Taşıyıcıları
Authors: KAYGUSUZ İbrahim
Published: June 2022

Modernleşme, on yedinci yüzyılda Avrupa’da başlayan, aydınlanma kültürünü ve kapitalizmin hayat tarzını dünyaya yayan toplumsal bir yaşam tarzıdır. Modernleşme ile birlikte başlayan çoğulculuk ve bireyselleşme süreçleri dinî bütünlükte ve kurumlaşmış dindarlıkta bir gevşeme ortaya çıkarmıştır. Modernleşmenin dinin anlam dünyası üzerindeki sarsıcı etkisi tasavvuf hareketlerinin geleneksel yapılarını ve kurumsal kimliklerini zayıflatmış ve fertle devlet arasındaki bu ikincil yapıların sosyal fonksiyonlarını yerine getirme becerilerini zayıflatmıştır. Çalışmada modernleşme sürecinin tasavvuf hareketleri üzerindeki etkisi ve günümüzde bu kültürün taşıyıcılarının kimler olduğu problemine odaklanılmıştır. Çalışmanın amacı, bilinç kalıpları içerici ve davranışları yönlendirici bir paket olarak gelen modernleşme sürecinin geleneksel dinî kurumlar üzerindeki dönüştürücü etkisini anlamaktır. Tarama yöntemiyle elde edilen nitel verilerin Berger ve Luckmann’ın tezleri çerçevesinde ele alındığı bu çalışmada, Cumhuriyet dönemi ile birlikte geleneksel formları aşan, modern kamusal yapılarla uyumlu ve bireyselleşmeyi belli düzeyde hoş gören yeni dinî grupların ortaya çıktığı ve bu grupların günümüzde tasavvuf kültürünün paydaş taşıyıcıları olduğu sonucuna ulaşılmıştır.
Tefsir Kaynaklarında Kadın Sahâbîlerin Kıraat Rivayetlerindeki Rolü
Authors: HAMURLI Mustafa
Published: June 2022

Kur’an ilimleri çok yönlü bir kavram olup içerisinde birçok ilim dalını barındırmaktadır. Bu ilimler arasında onu okumak, en doğru şekilde telaffuz etmek, farklı kıraatlerin cümleye kazandırdığı anlamları bilmek ve içerdiği hükümlerle amel etmek yer almaktadır. Kur’an’ın tefsiri ve hadislerin rivayet edilmesinde kadın sahâbîlerin büyük bir role sahip oldukları bilinmektedir. Ancak kıraat ilminde de bu yetkinliğe sahip olup olamadıkları merak konusudur. Kıraat ilminin teselsül yoluyla nakledilmesinde muhaddislerin belirlemiş olduğu isnâd sisteminin önemli role sahip olduğu müşahede edilmektedir. Bu sebeple kıraati nakleden kişinin, hocasından naklettiği rivayeti muttasıl bir senetle rivayet etmesi gerekmektedir. Dolayısıyla rivayet silsilesinin sahâbeye ulaşmaması veya senet içerisinde herhangi bir kopukluğun meydana gelmesi durumunda ilgili kıraat rivayeti reddedilmektedir. Kadın sahâbîlerin tefsir ve hadis alanlarında olduğu gibi kıraat nakillerinde de nispeten yer aldıkları görülmektedir. Bu çalışmada kıraat ilmine katkı sunan kadın sahâbîlerin kimler olduğu, kaç rivayet naklettikleri, naklettikleri bu rivayetlerin sahih ya da şâz kıraatler kapsamında değerlendirildiği konusuna açıklık getirilmesi hedeflenmektedir.
Psikolojik Savaş ve İslam’ın İlk Döneminde Bazı Uygulamaları
Authors: ERBİL Kadir
Published: June 2022

Soğuk savaşın bir türü olan psikolojik savaş, tarih boyunca hayatın her alanında farklı amaçlar için uygulanmıştır. Psikolojik savaşın bir yöntemi olan propaganda ise hedef kitleye karşı uygulanan bir iletişim şeklidir. Propaganda, özellikle savaş esnasında olayları çarpıtarak hedef kitleyi aldatmak için kullanılır. Psikolojik savaş ve propagandanın sosyolojik bir bakışla ele alınması, önemli bir araştırma konusudur. Bu bağlamda söylenti/dedikodu da hedef kitleyi yıpratmak için kullanılan bir taktiktir. İçeriği yanlış veya asılsız olsa bile söylenti/dedikodu toplumu etkileyerek insanları şüpheye düşüren, morallerini bozarak şevklerini kıran bir metottur.

Konu ile yakından ilgili olması nedeniyle çalışmamızda öncelikle psikolojik savaş, propaganda ve algı üzerinde durulmuştur. İslam’da psikolojik savaştan sonra Hz. Peygamber’e karşı uygulanan psikolojik savaşa değinilmiştir. Mekke müşriklerinin uyguladıkları kara propaganda ve psikolojik savaş üzerinde durularak gerekli yorumlar yapılmıştır. Çalışmanın konusu Mekke dönemi ile sınırlandırılmıştır.
Analisis Penerapan Prinsip–prinsip Good Corporate Governance Pada Usaha Kecil dan Menengah (Studi Pada UKM Restoran/Rumah Makan/Kafe di Daerah Cikupa Tangerang)
Authors: Yonita Veronica , Aprilyanti Rina
Published: June 2022

Penelitian ini bertujuan untuk mengetahui faktor-faktor apa saja yang berpengaruh terhadap pelaksanaan good corporate governance pada usaha kecil dan menengah khususnya pada usaha restoran/rumah makan/kafe. Dari kajian tersebut diambil lima faktor, yaitu penerapan prinsip transparency, penerapan prinsip accountability, penerapan prinsip responsibility, penerapan prinsip independency, dan penerapan prinsip fairness. Penelitian ini dilakukan dengan melakukan survey penyebaran kuesioner kepada para pemilik usaha restoran/rumah makan/kafe yang berada di wilayah Cikupa Tangerang yang diuji dengan pengujian asumsi klasik, metode analisis data serta analisis regresi linear berganda dan diolah menggunakan program SPSS (Statiscal Product and Service Solution) versi 23. Penelitian ini memperoleh hasil bahwa: (1) Penerapan Prinsip Transparency berpengaruh secara signifikan terhadap Pelaksanaan Good Corporate Governance Pada UKM. (2) Penerapan Prinsip Accountability berpengaruh secara signifikan terhadap Pelaksanaan Good Corporate Governance Pada UKM. (3) Penerapan Prinsip Responsibility tidak berpengaruh secara signifikan terhadap Pelaksanaan Good Corporate Governance Pada UKM. (4) Penerapan Prinsip Independency tidak berpengaruh secara signifikan terhadap Pelaksanaan Good Corporate Governance Pada UKM. (5) Penerapan Prinsip Fairness tidak berpengaruh secara signifikan terhadap Pelaksanaan Good Corporate Governance Pada UKM
Effectiveness of Quality of Seminar Services and Corporate Image on Consumer Satisfaction of Seminar Services
Authors: Ginny Puti Lenggo , Silaswara Diana , Parameswari Rinintha
Published: June 2022

This research on the effect of service quality and company image on customer satisfaction with seminar services was prepared using the associative method to examine two or more variables. Data collection used is questionnaire data. Every company engaged in seminar and sales services is oriented to achieve maximum profit by using minimal data sources. Therefore, marketing as a part of the company's body has a very important role for the development and survival of the company itself.Image is the most important tangible asset owned by the company. A good image can support the company's competitiveness and can also be a protection in times of crisis. Besides that, a good image can also be an attraction for executives and increase the effectiveness of marketing strategies and save operational costs.This study aims to determine how much influence service quality has on consumer satisfaction and corporate image at the Seminar Service Company. It can be seen from the results of the calculation of the correlation coefficient, which is 0.523 which means strong and the calculation of the coefficient of determination of 27.4% affects the company's image to consumers. And it can be seen from t count of 4.607 and t table of 1,978 which is greater than t count.So, by knowing the response of service quality and company image to customer satisfaction at the Seminar Service Company, it is hoped that it can provide input to satisfy consumers in improving the quality of service and company image that has been carried out.
Analisa Pengaruh Audit Tenure, Ukuran Perusahaan, dan Debt to Equity Terhadap Audit Delay
Authors: Subagja Edyana Halim
Published: June 2022

Tujuan dari penelitian ini adalah untuk menuji analisa pengaruh Audit Tenure, Ukuran Perusahaan, dan Debt to Equity terhadap Audit Delay. Audit Delay diukur dari selisih antara tanggal tutup buku perusahaan (30 Des) dengan tanggal pelaporan audit terhadap laporan keuangan yang telah diaudit oleh KAP. Data yang digunakan dalam penelitian ini adalah data sekunder yang merupakan laporan keuangan tahun 2012-2016 dari Bursa Efek Indonesia.Populasi penelitian ini terhadap perusahaan Consumer Goods yang terdaftar di BEI tahun 2013-2016 yaitu sebanyak 42 perusahaan. Sampel penelitian yang digunakan adalah sebanyak 23 perusahaan dalam periode 4 tahun. Sampel diambil secara purposive sampling yang memenuhi kriteria pemilihan sampel. Alat analisis data yang digunakan dalam penelitian ini adalah analisis statistik deskriptif, uji asumsi klasik, uji hipotesis yang terdiri dari uji parsial dan simultan, analisis regresi beganda dan uji Adjusted ????2. Teknik analisis data yang digunakan adalah regresi linier berganda dengan program SPSS 23 for windows.Hasil penelitian ini menunjukkan bahwa Audit Fee dan Debt to Equity secara parsial berpengaruh signifikan terhadap Audit Delay. Sedangkan Audit Tenure dan Ukuran Perusahaan secara parsial tidak berpengaruh signifikan terhadap Audit Delay. Nilai Adjusted R Square adalah 0,681 atau 68,1%. Hal ini berarti 68,1% variabel dependen yaitu Audit Delay dapat dijelaskan oleh keempat variabel independen. Sedangkan 31,9% dijelaskan oleh faktor-faktor lain diluar model
Analisis Penerapan Prinsip–prinsip Good Corporate Governance Pada Usaha Kecil dan Menengah (Studi Pada UKM Restoran/Rumah Makan/Kafe di Daerah Cikupa Tangerang)
Authors: Febianty Febianty
Published: June 2022

Berbagai trend baru dalam lingkungan manufaktur membawa dampak terhadap kualitas. Untuk dapat menghasilkan suatu produk yang berkualitas, maka perusahaan harus memperhatikan berbagai aspek seperti bahan baku, biaya produksi yang dikeluarkan, sumber daya perusahaan, serta manajemen kualitas produk tersebut.  Mengetahui pengaruh total quality management (TQM) terhadap kualitas produk yang dihasilkan dan mengetahui hubungan antara efisiensi biaya produksi terhadap peningkatan kualitas produk yang dihasilkan. Dilakukan penelitian deskriptif analitis dengan menggambarkan data yang diperoleh dan menganalisis data yang ada. Penelitian ini dilakukan dengan studi kasus untuk melakukan penelitian lebih mendalam sehingga dapat memberikan gambaran yang jelas dan lengkap. Melalui penerapan TQM, PT Busana Ragi Inovasi pada tahun 2017 mampu mengurangi produk cacat sebesar 23,55%, meningkatkan volume produksi sebesar 12,17%, efisiensi biaya produksi sebesar 1,49%. Oleh karena itu, PT Busana Ragi Inovasi mampu meningkatkan penjualan bersih sebesar 8,58% dan meningkatkan laba perusahaan sebesar 2,69% dari tahun 2016.  Penerapan TQM dan efisiensi biaya produksi pada PT Busana Ragi Inovasi mampu menunjukan bahwa perusahaan tetap dapat menghasilkan kualitas produk yang baik
Medicinal plants available in local markets contaminated with human pathogenic bacteria - Bacillus cereus and Pseudomonas gessardii
Authors: Rokon-Ud-Doula S M , Afrin Nazia , Sikder Md Maniruzzaman , Shilpi Rasheda Yasmin
Published: June 2022

Medicinal plants are known to be a potential source of therapeutic aids. Different uses of medicinal plants have attained a powerful role in health system throughout the world. To study the microbial risk factor associated with medicinal plants, medicinal plant and part of plant samples (10 from each location) were collected from three different local markets (Nabinagar, Amin Bazar, and Savar) of Savar area, Dhaka, Bangladesh. A total number of fifty five (55) bacterial isolates have been isolated through their growth on Nutrient Agar media. Out of 55 isolates 31 isolates (56%) were identified as Bacillus cereus and 7 isolates (13%) were identified as Pseudomonas sp. through different morphological and biochemical tests. The CFU value of different samples revealed that all the values were higher than the accepted value (recommended by WHO, 2007) of 105 CFU/g except Phyllanthus emblica. The PCR and 16S rRNA sequencing confirmed the identification similarity values among two isolates of B. cereus and Pseudomonas gessardii. Both B. cereus and Pseudomonas gessardii showed sensitivity to the antibiotics Kanamycin, Gentamycin, Tigecycline, Ciprofloxacin and Amikacin where resistance to the antibiotics Amoxycilin, Aztreonam, Penicillin-G, Cefixime, Cefotaxime, Cefepime, Ceftriaxone, Meropenem, Cotrimoxazole and Ceftazidime. Therefore, quality assessment of herbal medicines should be ensured to make them safer for human consumption.
Asian J. Med. Biol. Res. 2022, 8 (2), 69-78
A case-control study along with an epidemiological approach to CNTNAP2 polymorphism among Bangladeshi ASD children
Authors: Siddiqua Hafsa , Akter Yasmin , Mia Md Arju , Ahmed Mst Sharika , Chowdhury Mahmood Ahmed , Marzan Lolo Wal
Published: June 2022

ASD (Autism Spectrum Disorder) is a neuropsychiatric disorder with a hereditary component, and its prevalence in South Asia was assessed 1, out of every 93 children. Moreover, recent studies suggested that the etiology of autism is thought to be linked to anomalies in the synapse, where mutation or deletion of synaptic gene CNTNAP2 is responsible. Therefore, this research was aimed to find out specific signs and symptoms of ASD individuals as well as the distribution pattern of the CNTNAP2 allelic variant (rs7794745) as a genetic risk factor in the Bangladeshi population. A case-control study including an epidemiological survey to investigate the association and pathophysiology of CNTNAP2 (rs7794745) with ASD for the Bangladeshi population has been studied, where PCR-RFLP analysis and Sanger sequencing were used for 180 individuals (90 ASD samples and 90 healthy controls). Our retrieved data speculated a diverse clinical profile of ASD, in comparison to the control group (n=110); where 80.9% (p ≤0.001) of ASD patients (n =100) had severe social interaction difficulties, 50% (p ≤0.001) had language impairments, and 40.9% (p ≤0.001) had behavioral abnormalities. Furthermore, findings from Pearson’s chi-square test (p = 0.001) as well as logistic regression analysis of co-dominant (p = 0.0083), and recessive model (p = 0.0075) confirmed significant association between rs7794745 and in our studied sample. This research demonstrates the genetic variation of CNTNAP2 found in our studied population could open a new clue to identifying a reliable biomarker for early diagnosis of ASD though it is recommended that more study is needed with a larger group population.
Asian J. Med. Biol. Res. 2022, 8 (2), 79-93
Effect of hot water leaf and bark extract of Swietenia mahagoni against the Culex quinquefasciatus and Aedes aegypti larvae
Authors: Hasan Md Nazmul , Akter Tahmina , Junayed Md , Ahmad Saadia
Published: June 2022

Mosquito larvae control is essential to prevent mosquito borne diseases such as dengue, Zika, filariasis and chikungunya. Plant extract has the larvicidal properties with less toxicity to other living creatures and no resistance compared to synthetic chemical pesticides. Effect of hot water leaf and bark extract of a forest tree species (Swietenia mahagoni) against the 3rd instar larvae of Culex quinquefasciatus and Aedes aegypti was studied in vitro using five different concentrations (1-5%) of hot water leaf and bark extracts of Swietenia mahagoni. It was observed that, 5% concentrated hot water leaf extract was the most toxic killing 70% larvae of Culex quiquefasciatus and 50% larvae of Aedesa egypti after 24 hours exposure. Similarly, 5% hot water bark extracts killed 65% and 55% of Culex quiquefasciatus and Aedes aegypti larvae respectively. The minimum LC50, LC90 and LC95 values of hot water leaf extract of Swietenia mahagoni against Culex quinquefasciatus Say and Aedes aegypti (L.) with 95% confidence limits were 2.662, 6.968, 8.70 and 2.128, 4.964, 6.054 respectively after 72 hours of exposure. In hot water bark extract of Swietenia mahagoni against Culex quinquefasciatus Say and Aedes aegypti (L.) with 95% confidence limits after 72 hours of exposure minimum LC50, LC90 and LC95values were 1.780, 6.540, 9.458 and 1.370, 4.570, 6.430. The present investigation revealed the possible utilization of hot water leaf and bark extract of Swietenia mahagoni to control mosquito borne disease. Further study is needed to know the active ingredients of the leaf and bark extract of the experimented plant.
Asian J. Med. Biol. Res. 2022, 8 (2), 94-102
Efficacy of dry and wet carp pituitary gland (CPG) in the induced breeding of Cyprinus carpio var. specularis (Lacepède, 1803)
Authors: Sharif BM Newaz , Ghosh Antara , Mondal Subrata , Alam Mohammad Hasnal , Islam Md Ariful , Kabir Md Shamsul , Karim Md Manjurul
Published: June 2022

Fish hatcheries are generally regarded as the first step in the process of aquaculture development in any given nation. Fish breeding plays an important part in the process of supplying fry and fingerling to the farmers. The current study was conducted to identify the effectiveness of using dry and wet carp pituitary gland (CPG) in the induced breeding of mirror carp (Cyprinus carpio var. specularis), at Banchte Sheka fish hatchery Arabpur, Jashore from November to December 2021. The 1st dose of hormone, both for male and female brood fishes were injected with dry & wet PG at 0.8 mg PG/kg body weight. After 6 hours of the 1st dose, only female brood fishes were injected with the 2nd dose of hormone at 3 mg PG/kg body weight. After 6-7 hours of injection of 2nd dose, brood fishes became ready to spawn. The fertilized eggs were hatched after 42-48 hours. The ovulation rates were 100%. The fertilization rates were 88.3 % and 91.2% for wet and dry PG, respectively. The hatching rates were 84.2% and 87.5%, respectively. The survival rates were 79.5% and 83.3%, respectively. Therefore, dry CPG is highly recommended to hatchery owners considering the rate of fertilization, survival rate and availability. The information that has been offered here will be helpful to the owners of hatcheries when it comes to choosing the sort of pituitary gland to use in the breeding operation.
Asian J. Med. Biol. Res. 2022, 8 (2), 115-122
Medicinal plants used by the tribal communities of Thanchi Upazila in Bandarban Hill District, Bangladesh
Authors: Alam Md Sah , Rahman M Mahfuzur , Hossain Mohammed Kamal , Ray Tusher Kumer
Published: June 2022

Medicinal plants play in an important role in the primary health care system. The paper deals with the indigenous knowledge related to ethnomedicinal knowledge and plant parts application for curing various ailments by the ethnic community of Thanchi Upazila of Bandarban Hill District. Semi-structured questionnaires, interviews, group discussions, and specific plant sample collection were done from July 2019 to December 2021 to procure ethno-medicinal data from local herbalists and elderly villagers for this study and from the forest areas. A total of 129 plant species under 110 genera and 63 families have been documented, which have been traditionally used by the ethnic people for the treatment of different ailments. Traditional knowledge and information about medicinal plants such as local names, scientific names, families, habits, habitats, plant-parts used, names of ailments, modes of use, etc. were recorded, validated, and documented. Plant families namely, Asteraceae and Euphorbiaceae were represented by the highest (8) number of species, followed by Fabaceae, Verbenaceae, Apocynaceae, Araceae, Caesalpiniaceae, Lamiaceae, Rubiaceae and Zingiberaceae. The most widely used medicinal plants included Anacardium occidentale, Bombax ceiba, Calotropis gigantea, Terminalia chebula, Aegle mermelos, Ageratum conyzoides, Andrographis paniculata, Aristolochia indica, Blumea balsamifera, Bryophyllum pinnatum, Celosia cristata, Centella asiatica, Melastoma malabathricum, Mimosa pudica, Musa paradisiaca, Oroxylum indicum, Plumbago indica and Vitex negundo. Herbs (36%) were found to be the most used plant, followed by shrubs (33%), trees (17%), climbers (9%) and fern (5%). Most medicinal plants were used for the treatment of fever, skin diseases, cough problems, menstrual problems, body pain, indigestion, headaches, stomachaches, constipation, swelling problems, wounds and others. Among the plant parts, mostly leaves were used (43%), followed by roots (21%), whole plants (10%), stems (6%) along with fruit, rhizome, flower, bark, seed and latex for the treatment of diseases. The most common formulations prescribed to treat various diseases were juices. The findings will be useful for future research in the Bandarban Hill District.
Asian J. Med. Biol. Res. 2022, 8 (2), 123-140
Floristic Survey of Vascular Plants in Coastal District Bagerhat of Bangladesh
Authors: Hossain Gazi Mosharof , Khan Saleh Ahammad , Shetu Shayla Sharmin , Rahman Mohammad Sayedur , Ahmed Fakhruddin Ali , Ali Md Hassan
Published: June 2022

This survey provides the basic taxonomic data on the vascular flora of the disasterprone coastal district of Bagerhat. It has explored the occurrence of 964 species of vascular plants under 607 genera and 147 families in this district. About 68.88% of these species are native and 31.12% are exotic to Bangladesh. Pteridophytes are composed of 32 species under 22 genera of 14 families and Gymnosperms of seven species under six genera and five families. Angiosperms are comprised of 693 species of 450 genera and 99 families of Magnoliopsida (dicotyledons) that represent 71.89% of the flora, and 232 species belonging to 129 genera under 29 families of Liliopsida (monocotyledons) that constitute 24.07% of this flora. Fabaceae with 58 species is the largest dicot family, followed by Asteraceae, Euphorbiaceae, Apocynaceae, and Acanthaceae. Poaceae with 68 species is the largest monocot family, followed by Cyperaceae, Orchidaceae, Araceae and Arecaceae. The genus Cyperus is the largest in the study area, which is followed by Fimbristylis, Euphorbia, Ficus, Solanum and Ipomoea. The species Cipadessa baccifera (Roth) Miq. of Meliaceae is rediscovered in Bangladesh. About 63.35% of species of this flora and most of the Magnoliopsida and Liliopsida are herbs, 18.94% shrubs, 15.63% trees, and 1.55% palms. Nearly 70.81% of the species are wild and the rest are planted or cultivated. 17 species are recognized as rare in the study area due to their very restricted occurrence and poor regeneration. Most of the species grow in the fallow lands, roadsides, woodlands, homesteads, marginal lands and scrub jungles. The majority of the species have more than one uses, but most are useful as medicinals (70.39%) and ornamentals (25.57%). Though the study area is under the stress of different threats, its floristic composition is still rich. We strongly recommend adopting adequate effective measures for the conservation and sustainable development of this rich flora of the coastal region.
Bangladesh J. Plant Taxon. 29(1): 43-78, 2022 (June)
Tropaeolaceae: A New Family Record for the Flora Of Saudi Arabia
Authors: Al robai Sami Asir , Mohamed Haidar Abdalgadir , Ahmed Abdelazim Ali , Kordofani Maha Ahmed
Published: June 2022

The family Tropaeolaceae was reported for the first time in Saudi Arabia. The new record (Tropaeolum majus L.) from the Tropaeolaceae family was found in damp and exposed semi-shaded habitats between roughly 1800 and 2132 m elevation in southwestern Saudi Arabia. Illustrations, photos, taxonomic description, distribution map, key and information about the habitat of the plant were given. This study suggests that the new record is an introduced alien plant into Saudi Arabia.
Bangladesh J. Plant Taxon. 29(1): 79-84, 2022 (June)
Systematic Studies of the Genus Asparagus Tourn. Ex Linn. (Liliaceae) In Bangladesh
Authors: Afroz Sumona , Rahman M Oliur , Hassan Md Abul
Published: June 2022

The genus Asparagus Tourn. ex Linn. represented by five species in Bangladesh, viz., Asparagus adscendens Roxb., A. densiflorus (Kunth) J.P. Jessop, A. officinalis L., A. racemosus Willd. and A. setaceus (Kunth) J.P. Jessop is revised. Each species is described with updated nomenclature, important synonyms, phenology, specimens examined, chromosome number, habitat, distribution, economic value and mode of propagation. A dichotomous bracketed key to the species and illustrations along with photographs of four species are provided.
Bangladesh J. Plant Taxon. 29(1): 97-107, 2022 (June)
Ethnomedicinal Plant Diversity in Badalchori Vadi Sora Village Common Forest of Rangamati, Bangladesh
Authors: Rudra Sajib , Chowdhury Md Helal Uddin , Hossen Imam , Raziur Rahman Md Khondakar , Hossain Md Arif , Faruque Mohammad Omar , Uddin Shaikh Bokhtear
Published: June 2022

A total of 209 species were documented where 181 species were used against 379 diseases/ailments from a village common forest of Rangamati, Bangladesh. Leaves were reported as most utilized plant part while herbs were dominant. Diversity indices revealed that the study area was rich in diverse medicinal plants. Collected voucher specimens were deposited in the Chittagong University Herbarium with an accession number.
Bangladesh J. Plant Taxon. 29(1): 109-128, 2022 (June)
Development of methods for quantification of gelatin in vegetable capsule shell and for classification of capsule shell as from vegetable or animal sources by chemometric analysis of FTIR spectroscopic data
Authors: Debnath A , Uddin MN , Jahan RA , Rana AA , Karim MM
Published: June 2022

Capsule shell from animal source (bovine or porcine gelatin) is a problem for the follower of different religions and vegetarian. In that case, vegetable capsule shell could be a solution. In this research, we proposed a simple and cost-effective technique for detection of gelatin in vegetable capsule shell and for classification of capsule shell by source, based on Chemometric techniques with FTIR spectroscopic data. Partial Least-Square Regression (PLSR) models were developed and their efficiencies were assessed with spectroscopic data of range of 4000-700 cm-1. PLSR shows very good prediction efficiency (R2= 98%) for both vegetable capsule shell and gelatin. In addition, Soft Independent Modeling by Class Analogy (SIMCA) classification method were developed and assessed with spectral data of capsule shells from vegetable and animal sources. Results prove that FTIR spectroscopy in combination with chemometric method can be used for the classification of capsule shell by source and quantification of gelatin in vegetable capsule shell to ensure their authenticity.

Bangladesh J. Sci. Ind. Res. 57(2), 91-98, 2022
Mononuclear cobalt(III) azido complex containing a tetradentate amine: one pot synthesis, structure and thermal behavior
Authors: Khan Sumitava
Published: June 2022

One hexacoordinated mononuclear complex trans-[Co(L)(N3)2] PF6 (1) [L = N,N′-bis(3-aminopropyl)- 1,2-ethanediamine] is prepared by using one-pot reactions of the building units and characterized. X-ray analysis shows that cobalt center in 1 adopts a distorted octahedral geometry with CoN6 chromophore ligated through four N atoms of tetradentate amine (L) and the two N atoms of terminal azides in mutual trans orientation. In the crystalline state, double N-H…N and multiple N-H…F hydrogen bondings result in 2D sheet structure. The compound has a thermal stability up to 193°C.

Bangladesh J. Sci. Ind. Res. 57(2), 109-116, 2022
Identification of Natural Compounds with Anti-SARS-CoV-2 Activity using Machine Learning, Molecular Docking and Molecular Dynamics Simulation Studies
Authors: Arifuzzaman - , Mohammadi Mohadese , Rupa Fatema Hashem , Khan Mohammad Firoz , Rashid Ridwan Bin , Rashid Mohammad A
Published: June 2022

The coronavirus pandemic of 2019 (COVID-19) has adversely affected public health and the socioeconomic situation worldwide. Although there is no therapeutic drug to treat COVID, several treatment options are being considered to alleviate symptoms. Hence, researches on prophylactic treatment for COVID are being encouraged. Searching natural products is a rational strategy since it has served as a valuable source of lead compounds in drug discovery. In this study, three machine learning approaches, including Support Vector Machine (SVM), Random Forest (RF) and Gradient Boosting Machine (GBM), have been used to develop the classification model. The molecular docking was performed on AutoDock vina. Further, molecular dynamics (MD) simulation of the potential inhibitors was conducted using the AmberTools package. The accuracy for SVM, RF and GBM was found to be 60.45 %, 63.43 % and 64.93 %, respectively. Further, the model has demonstrated specificity range of 41.67 % to 50.00 % and sensitivity range of 74.32 % to 79.73 %. Application of the model on the NuBBE database, a repository of natural compounds, led us to identify 322 unique natural compounds, likely possessing anti-SARSCoV- 2activity. Further, molecular docking study has yielded three flavonoids and one lignoid compounds with comparable binding affinities to the standard compound. In addition, MD showed that these compounds form stable complexes with different magnitude of binding energy. The in silico investigations suggest that these four compounds likely demonstrate their anti-SARS-CoV-2activity by inhibiting the main protease enzyme. Our developed and validated in silico high-throughput investigations may assist in identifying and developing antiviral drug-like compounds from natural sources.
Dhaka Univ. J. Pharm. Sci. 21(1): 1-13, 2022 (June)
Qualitative Phytochemical Screening, Fatty Acid Composition Analysis and Biological Studies of Trianthema portulacastrum L. Leaves
Authors: Chowdhury Vaskar , Shristy Nusrat Tabassum , Rahman Md Hasanur , Chowdhury Tofail Ahmad
Published: June 2022

Trianthema portulacastrum L. commonly known as ‘horse purslane’ and locally called ‘shvetapunarnava’ is an annual broadleaf plant of tropical areas throughout the world. In this study, determination of moisture and ash content of the plant leaves, as well as qualitative phytochemical test, cytotoxicity assay, antimicrobial activity, fatty acid composition, total phenolic content, total flavonoid content, total antioxidant capacity, and DPPH radical scavenging activity were carried out. Methanol extract of T. portulacastrum leaves was partitioned using Kupchan's method with different solvents of increasing polarity (n-hexane, dichloromethane, chloroform, ethyl acetate). The moisture and ash contents of the leaves were (81.74±0.49)% and (31.05±1.36)%, respectively. Initial phytochemical screening of T. portulacastrum showed the presence of alkaloids, tannins, flavonoids, and tri-terpenoids. In fatty acid composition analysis, both bound fatty acids and free fatty acids were isolated from n-hexane extract that showed the presence of the highest percentage of palmitoleic acid (67.095% and 48.843%, respectively) and stearic acid (12.14% and 20.437%, respectively). Dichloromethane and methanol extracts were found to be cytotoxic on HeLa cells in cytotoxicity assay against Vero, HeLa, and BHK-21 cell lines. The highest phenolic content was observed in ethyl acetate extract (68.55±0.038 mg/g) and the highest flavonoid content was found in chloroform extract (477.01±0.104 mg/g). The DCM fraction revealed the highest total antioxidant capacity (284.99±0.113 mg/g), and the IC50 value for ethyl acetate extract was the lowest (110.35±0.160 μg/ml) of all the extracts.
Dhaka Univ. J. Pharm. Sci. 21(1): 33-43, 2022 (June)
Isolation, Characterization and Identification of Selected Microorganisms from Wildlife Geophagic Soil: A Probe of Pros and Cons
Authors: Adewale Rilwan O , Onasanya Oluwatosin T , Oguntade Oladele A , Odebiyi Babajide R , Akinsorotan Oluseun A , Olorunisola Kola S , Sule Shakiru O , Oso Olusesi A
Published: June 2022

The search for novel antibiotics for treating human-wildlife infections has not stopped. This study isolated and characterized bacteria and fungi from wildlife geophagic termite mounds (TMs) using standard microbiological procedure. Four composite samples of TMs evident to be eaten by wildlife were randomly collected (TM1, TM2, TM3 and TM4) in addition with a composite forest soil (FS5) that showed no sign of consumption. With the use of appropriate media, all samples were subjected to microbiological analysis covering morphological, biochemical (for bacteria), colonial and cellular morphology (for fungi). Bacteria and fungi cells isolated and characterized from respective soil samples include; Streptomyces lydicus/Aspegillus niger (TM1), Paenibacillus polymyxa/Penicillium digitatum (TM2), Pseudomonas fluorescens/Fusarium spp. (TM3), Bacillus subtilis/Aspergillus flavus (TM4) and Acinetobacter radioresistens/Geotricihum candidum (FS5), all of which have both beneficial and harmful characteristics. Wildlife may be affected by pathogenic organisms when consuming TMs for medicinal reasons.
Dhaka Univ. J. Pharm. Sci. 21(1): 53-58, 2022 (June)
Antioxidant, Analgesic, Antimicrobial and Molecular Docking Studies of the Leaves of Oroxylum indicum (L.) Kurz.
Authors: Sultana Arifa , Spriha Sabiha Enam , Rahman SM Abdur
Published: June 2022

This study presents the findings of in vivo, in vitro and in silico investigations of the Oroxylum indicum (L.) Kurz leaf extracts. Various fractions namely chloroform (CF), ethyl acetate (EAF), n-hexane (HF) and aqueous fractions (AF) obtained from the crude extract were subjected to biological investigations. In DPPH based free radical scavenging assay, CF and MF fractions showed potent antioxidant activity with IC50 9.70 g/ml and 10.46 g/ml as compared to IC50 8.56g/ml for the standard ascorbic acid. The CF and HF fractions of O. indicum (L.) Kurz leaves exhibited mild antimicrobial activity. In analgesic activity screening by acetic acid induced writhing method, EAF showed significant writhing inhibition of 68% and 72%, at doses 150 mg/kg and 300 mg/kg, respectively. In tail immersion method, EAF also showed potent analgesic activity with reaction time of 1.816 ± 0.047 and 2.15 ± 0.041 min, after 30 minutes following oral doses of 150 mg/kg and 300 mg/kg, respectively. Molecular docking of previously isolated compounds from O. indicum (L.) Kurz leaf extracts were docked against cyclooxygenase-1 (COX-1) and cyclooxygenase -2 (COX-2) and revealed that the flavonoids baicalein and chrysin may be responsible for the analgesic activity. Lipinski’s rule of five was also calculated for the compounds to assess drug likeliness.
Dhaka Univ. J. Pharm. Sci. 21(1): 85-94, 2022 (June)
Review on Some Bangladeshi Medicinal Plants with Anticancer Properties
Authors: Ashrafi Sania , Masud Mohammad Mehedi
Published: June 2022

According to WHO, cancer is one of the leading causes of death worldwide, accounting for an estimated 9.6 million deaths in 2018. More significant improvements have been made in the management and treatment of cancer, still there remains scope for the betterment of treatment procedures. Mostsynthetic anticancer drugs are known to develop resistance, show cytotoxicity against normal cells due to their non-selective nature, and cause tremendous side effects. Medicinal plants are significantly feasible sources of organic compounds, for their better availability, cheaper price, fewer side effects, and sometimes better therapeutic efficacy, which may benefit the world commercially or act as an important starting point for identifying lead compounds to develop modified derivatives. This article describes the ethnobotanical properties of 15 available medicinal plants of Bangladesh having anti-cancer properties.
Dhaka Univ. J. Pharm. Sci. 21(1): 95-104, 2022 (June)
ANALISIS RESPON MAHASISWA FKIP UNIVERSITAS JEMBER TERHADAP KERUSAKAN FUNGSI SUNGAI DAN DAMPAK YANG DITIMBULKANNYA
Authors: Diniarti Yunita Sari Ayundah
Published: June 2022

The activity of disposing of waste and other polluting items into the river pollutes the river and has a big impact on living things. The inappropriate use of the river causes damage to the function of the river. This problem cannot be resolved in a short time, it takes self-awareness of each community to overcome these problems. As a student who is considered a young man who can make changes to the nation, each student should feel sympathy and an effort to spark ideas for solving the problems above. However, in fact there are not many students who have good responses to the above problems, so a study is needed to see the extent to which students respond to these problems. The purpose of writing this article is to find out how the 3rd semester students of Jember University respond to the damage to the function of the river and its impacts. This study used the subjects of several FKIP students, University of Jember semester 3, batch 2019. The above research was conducted using quantitative and qualitative methods. The results showed that the response of the students regarding the damage to the function of the river and the impacts it caused was quite good which can be seen from the high percentage value found in the table of the results of the description of student responses on indicators two to four. However, in the first indicator there are still deficiencies in student responses to innovations in preventing damage to river functions.
ANALISIS RESPON MAHASISWA TERHADAP PEMILAHAN SAMPAH RUMAH TANGGA MELALUI PENGELOLAAN SAMPAH BERBASIS ZERO WASTE
Authors: Sudarti . , Nadhiroh Afifah Khansa
Published: June 2022

Waste has great potential in local environmental conditions, especially for health, including household waste. The more the population and the industrial growth rate have increased, the more waste will be produced. Zero waste based management is capable of selecting, composting, and collecting saleable items. This study aims to Analysis of college student responses to household waste sorting through waste management based on zero waste. This research design uses descriptive method with research samples aimed at Jember University students. As for the sampling technique of 73 respondents, where data collection was carried out by structured interviews through questionnaires. The results showed that the college students' response at the University of Jember was good and played an active role in sorting household waste through zero waste based management. However, some students still have not implemented it in their habit of disposing of garbage every day. It can be seen that 54.8% of respondents only collect garbage and 34.2% of respondents burn garbage.
UJI KUALITAS MIKROBIOLOGI DAN KIMIAWI SEDIAAN YOGHURT BERBAHAN DASAR KACANG BOGOR (Vigna subterranea)
Authors: Agustina Rika Sri , Haryani Tri Saptari , Ismanto .
Published: June 2022

Yogurt is milk fermented with Lactobacillus bulgaricus and Streptococcus thermophilus bacteria. Yoghurt is derived from milk, which is a source of protein, one source of vegetable protein is bambara groundnut milk. The purposes of this research are to determine the quality of yoghurt made from bambara groundnut through microbiological and chemical tests and to determine the concentration of milk and the optimal fermentation temperature for making yoghurt with the best quality. This research used a completely randomized factorial design with the concentration of bambara groundnut milk of 15%, 20%, and 25% and the fermentation temperature of 35°C, 40°C, and 45°C and a four-time repetition. The result of this research shows that the best quality of yoghurt made from bambara groundnut was obtained from the treatment of bambara groundnut milk with the concentration of 20% and the fermentation temperature of 45°C with the results of total coliform, Salmonella sp., Listeria monocytogenes, total lactic acid bacteria, bacterial morphology, protein, acidity, fat and organoleptic respectively: 0 MPN/gram, negative/25gram, negative/25gram, 2.6x109 colonies/gram, circular shape, milky white, convex elevation, Gram positive, 3.74%, 1.77 %, 0.68% and liked by panelists.
UJI AKTIVITAS EKSTRAK Padina australis SEBAGAI ANTIBAKTERI Propionibacterium acnes PENYEBAB JERAWAT
Authors: Widjaya Vira Mourena Putri , Komala Oom , Ismanto .
Published: June 2022

The apperance of acne is a problem for many suffers because can lower confidience and shame. Many people have attempted to treat or eliminate acne, that is by antibiotic. However of antibiotic clearly has side effects, and the ultilization of natural material is the solution. One of them is Padina australis which contains flavonoid, tanin dan saponin potentially as an antibacterial. The purpose of this research is to derermne the concentration of Padina australis extract with methanol 98% which has optimal activity in improving the growth of Propionibacterium acnes based on inhibition zone test and minimum inhibitory concetration (MIC). Qualitative phytochemical test were carried out on alkoloids, flavonoids, saponins, tannin and steroids. Testing these bacteria using disc dffusion methods. MIC of Padina australis extrct used dilution method with concentrtaion of 3.75%, 7.5%, 15% and 30%. Inhibition zone test used disc diffusion method with concentrtaion of 60%, 80% and 100%. The result of phytochemical screening testing Padina australis extrct test showed that there are secondary metabolite compounds alkoloids, flavonoids, saponins, tannin and steroids. MIC test of Padina australis extrct against Propionibacterium acnes occured at a concentration of 30% and the inhibition zone test was found at concentration of 100% which was the most optimal in inhibiting with an average of the inhibition zone width 6.20 mm.
ANALISIS PENGEMBANGAN WISATA ALAM AIR TERJUN WIDURI SEBAGAI KAWASAN EKOLOGI PARIWISATA
Authors: Nasikhah Lailiyatun , Fikri Achmad Ali
Published: June 2022

Widuri Waterfall has its own uniqueness compared to other tourist attractions in Grobogan. The natural nature of the Widuri Waterfall is the main attraction for visitors. This study aims to explore how the development of ecotourism in the Widuri waterfall area has applied the principles of ecotourism or not. This research is included in the field research, with a qualitative approach and descriptive analysis. Data collection techniques in the form of interviews, observation and literature study. Based on the research that has been carried out, it is found that in tourism development every year holding environmental conservation activities, every tree around the tourism is given a name and its benefits, then tourism development has also involved the role of the local community. It can be concluded that the development of Widuri waterfall tourism has met the requirements of the principles of eco-friendly tourism development, namely the existence of the principle of conservation, the principle of education, the principle of tourism, the principle of economics and the principle of community participation. Researchers suggest to managers to continue to evaluate continuously in the development of ecotourism Widuri waterfall so as not to disturb and damage the function of the natural environment around the Widuri waterfall area. With this research, it is hoped that tourism managers will continue to pay attention to the principles of tourism development based on the principles of ecological development. Keywords: Development, Ecotourism, Waterfall
KEANEKARAGAMAN INSEKTA (ORDO LEPIDOPTERA) DI PUSAT SUAKA SATWA ELANG JAWA BOGOR
Authors: Krismawanti Rizky , Rostikawati Teti , Prasaja Dimas
Published: June 2022

The Javan Eagle Wildlife Sanctuary Center (PSSEJ) is one of the regions in Indonesia that has a high diversity of flora and fauna in Bogor, West Java. One of the fauna that live in PSSEJ is an insect of the order Lepidoptera. The limited information about Lepidoptera in this location causes the data on the diversity of these species to not be known with certainty. It is necessary to research the diversity of Lepidoptera. This study aims to study the species diversity of the order Lepidoptera at the Javan Eagle Wildlife Sanctuary Center. This research is an exploratory research conducted from December 2020 to August 2021 in two routes, namely track 1 (camping ground area) and route 2 (officer entrance route and land use). The research method uses a survey method using a sweeping net technique. Collecting data in the form of primary data covering the number of Lepidoptera species and secondary data covering temperature, humidity and light intensity. Based on the research, it was found 39 species of the order Lepidoptera with a moderate diversity index of 2.84, a high evenness index of 0.87 and a low dominance index of 0.08. Keywords: Diversity, Javan Eagle Sanctuary Center, Lepidoptera