bluuebunny/crossref_metadata_2025 huggingface dataset:
Method development, validation, and impurity measurement of β-estradiol from radiolabeled [131 I]β-estradiol using radio-high-performance liquid chromatography for radioligand of saturation binding assay
Authors: Daruwati Isti , Gwiharto Abednego Kristande , Wongso Hendris , Achmad Tri Hanggono , Syaifudin Mukh , Muchtaridi Muchtaridi
Published: April 2023

β-estradiol is an estrogen steroid hormone and acts as an estrogen receptor agonist. Radiolabeled β-estradiol is widely used as a radioligand for binding assays. In this present study, the synthesis of [131I]β-estradiol has been successfully carried out. Accordingly, the measurement of the radiochemical purity (RCP) value and the presence of chemical impurities are needed. To validate the method for identifying the RCP and chemical impurities from [131I]β-estradiol using high-performance liquid chromatography (HPLC). The synthesis of [131I]β-estradiol was accomplished by a radioiodination reaction, and the RCP was determined by radio-HPLC. The method for β-estradiol measurement was validated by reversed-phase HPLC radio-analytical employing ultraviolet-visible (UV-Vis) and radioactive detector. The method for radio-HPLC analysis was validated and established using a C-18 column and MeCN: H2O (55:45 v/v) as the mobile phase. The following conditions were applied: a flow rate of 1.2 mL/min, isocratic, and a UV-Vis detector at 280 nm. The RCP of [131I]β-estradiol measured by thin-layer chromatography and radio-HPLC was 99.27% ± 1.25% and 95.75% ± 2.41%, respectively. The validation parameters were appropriate and met the requirements for acceptance. HPLC analysis was able to identify the presence of unlabeled estradiol (24.51%–27.29%) in the mixture of [131I]β-estradiol. As a result, purification using preparative HPLC or other methods will be required in future studies.
Solvent preextraction influenced to coumarin and glucose binding capacity of cinnamomi's extracts
Authors: Ervina Martha , Wea Virgiana Kristin Coco , Oktaviani Annisah , Hartanti Lanny , Sinansari Restry , Wilianto Yufita Ratnasari , Steven  , Caroline
Published: April 2023

Cinnamon is one of the world's oldest spices that is also widely used as medicine for antimicrobe, anti-inflammation, and immune stimulant to now developed as an antidiabetic herbal medicine. Among its bioactive contents, the coumarin must have been controlled; since of its toxicities. Therefore, in this study aimed to reduce the amount of coumarin in the extracts by chloroform preextraction to dried powdered cinnamons and determine their glucose binding capacity. The extractions were used two methods by water infusion and ethanol soxhletation. To measure the coumarin's was used validated thin-layer chromatography (TLC)-densitometry, while for the chemical profiling of the extract was examined with liquid chromatography–mass spectrometry. The activity antidiabetic of the extracts was obtained by glucose binding. The TLC-densitometry method has been validated with silica gel 60F254 and n-hexane: ethyl acetate (8:2, v/v) systems. The coumarin's spot was observed at a wavelength of 285 nm on retention factor (Rf) 0.33, with tailings factor 1. The intraday and interday linearities tests showed a linear response result. The recovery value, coefficient of variation, and detection and a quantitation limit were met the standard requirements, respectively. Moreover, the results were observed (1) the solvent preextraction may reduce the coumarin content, (2) the coumarin content in the ethanol extract was higher than in the infusion, and (3) the preextraction solvents would reduce the glucose-binding capacity in ethanol and water cinnamomi's extract. These results may be developed further and applied for producing cinnamon's free coumarin extracts.
Adverse Events Following COVID-19 Vaccination in Rivers State, Nigeria
Authors: Harry Agiriye Monima , Edet Clement Kevin , Ekanem Nyarawo Effiong , Kemdirim Chinonye Judith , Uduak Abasianam Etuk
Published: April 2023

Context:

Coronavirus disease (COVID-19) has led to over 2,589,638 deaths globally as of March 2021 and speedy discovery of vaccines. Nigeria started the phase one COVID-19 vaccination in March 2021 using the Oxford AstraZeneca vaccine. Reports of severe adverse events with the Oxford AstraZeneca vaccine resulted in its suspension in some countries necessitating the need to determine its safety.

Aims:

To assess the prevalence, types and severity of the adverse events following COVID-19 vaccination in Rivers State, Nigeria.

Settings and Design:

A cross-sectional study design was adopted.

Subjects and Methods:

Simple random sampling method was used to select a total of 428 adults from recipients of the first dose of COVID-19 vaccine within 28 days of vaccination. A questionnaire adapted from World Health Organisation was interviewer-administered through phone calls; responses were recorded on Kobo Toolbox.

Statistical Analysis Used:

Descriptive analysis of variables was done and the association between adverse events and age, allergy and medical history were determined. The level of statistical significance was predetermined at aP< 0.05.

Results:

In this study, 50.5% of respondents reported post-vaccination adverse events out of which 10 (4.6%) were severe (30% of the severe cases were life-threatening, 60% were hospitalised and 10% were placed on bed rest). The most common side effects were fever (73.0%), pain at the injection site (41.2%), fatigue (33.3%), body ache (17.5%) and headache (13.8%). No significant association was observed between the incidence of severe adverse events and participants with allergies or medical history.

Conclusions:

The adverse events associated with the COVID-19 vaccine were largely mild and resolved within a few days. Further research is required to classify adverse events into categories.
Study on Creep Function of one P1P4 Vehicle with Torque Converter
Authors: Huang Wenkai
Published: April 2023

The creeping speed of vehicles with torque converter varied with the engine idle speed. In traditional vehicles, it happened on cold engine or transmission condition obviously. But in P1P4 hybrid vehicles, due to more engine start and stop and power regeneration, the engine water temperature was not easily to keep over 90°C, which lead to higher engine idle speed when engine was on. Thus, due to the impeller pump torque varying with engine idle speed, the creeping torque changed, which lead to the inconsistency of vehicle creeping speed. In P1P4 target vehicle, a new software was developed to solve this problem with new torque split. After verification and calibration, the new software was released.
Effective Second Moment of Load Path (ESMLP) Method for Multiaxial Fatigue Damage and Life Assessment
Authors: Wei Zhigang , Dong Pingsha , Pei Xianjun
Published: April 2023

Time-domain and frequency domain methods are two common methods for fatigue damage and life assessment. The frequency domain fatigue assessment methods are becoming increasingly popular recently because of their unique advantages over the traditional time-domain methods. Recently, a series of moment of load path based multiaxial fatigue life assessment approaches have been developed. Among them, the most recently developed effective second moment of load path (ESMLP) approach demonstrates its potentials of conducting fatigue damage and life assessment accurately and efficiently. ESMLP can be used for fatigue analysis even without resorting to cycle counting because of its unique mathematical and physical properties, such as quadratic form in the kernel of the moment integral, rotationally invariant, and being proportional to damage. Developing a better parameter for frequency-domain analysis is the driving force behind the development of ESMLP as a new fatigue damage parameter. The time domain properties and applications of ESMLP have been demonstrated recently, and it is found that ESMLP works well in correlating time-domain data including asynchronous test data.

In this paper, the basic mathematical structures and key features of ESMLP in frequency domain are presented. Procedures of implementing ESMLP into frequency-domain analysis are provided. Examples of well-studied loading paths, such as ASTM 1049 uniaxial loading examples and multiaxial (synchronous and asynchronous) loading cases, are analyzed and presented to demonstrate ESMLP based frequency-domain assessment procedure. The potentials of ESMLP in frequency-domain analysis of variable amplitude multiaxial fatigue data and knowledge-informed machine learning are also discussed.
Vehicle Lateral Offset Estimation Using Infrastructure Information for Reduced Compute Load
Authors: Sharma Sachin , Fanas Rojas Johan , Ekti Ali Riza , Wang Chieh (Ross) , Asher Zachary , Meyer Rick
Published: April 2023

Accurate perception of the driving environment and a highly accurate position of the vehicle are paramount to safe Autonomous Vehicle (AV) operation. AVs gather data about the environment using various sensors. For a robust perception and localization system, incoming data from multiple sensors is usually fused together using advanced computational algorithms, which historically requires a high-compute load. To reduce AV compute load and its negative effects on vehicle energy efficiency, we propose a new infrastructure information source (IIS) to provide environmental data to the AV. The new energy–efficient IIS, chip–enabled raised pavement markers are mounted along road lane lines and are able to communicate a unique identifier and their global navigation satellite system position to the AV. This new IIS is incorporated into an energy efficient sensor fusion strategy that combines its information with that from traditional sensor. IIS reduce the need for camera imaging, image processing, and LIDAR use and point cloud processing. We show that IIS, when combined with traditional sensors, results in more accurate perception and localization outcomes and a reduced AV compute load.
Recenzii
Authors: Barbu Cătălina
Published: April 2023

Marian Drăgoi, Economia mediului. Editura Universității ”Ștefan cel Mare” Suceava 2022, 140 p. ISBN 978-973-666-728-2
In situ determination of crop productivity in metal-contaminated, remediated, and reclaimed soils: Significance of ecotoxicological data on assessing soil quality
Authors: Kim Shin Woong , Nam Sun-Hwa , Kwak Jin Il , Chae Yooeun , Kim Dokyung , Jeong Seung-Woo , An Youn-Joo
Published: April 2023

Soil quality assessment is generally performed using a combination of physical, chemical, and biological indicators in a target area, and the indicator measurement data are subjected to sequential processes such as scoring, weighting, and indexing. The selection of indicators is one of the important processes, and their actual application should be carefully considered. The techniques of soil remediation can affect the measurement of traditional biological indicators. In the present study, we aimed to evaluate the applicability of ecotoxicological indicators for soil quality assessment. The paddy and upland soil plots were constructed using contaminated-, remediated-, and reclaimed-soils on field, and the soil quality indicators were measured. We designed a soil quality assessment system including ecotoxicological indicators, and the soil quality index (SQI) was calculated using indicator measurement data of each plot. The SQI with or without ecotoxicological indicators was directly compared with in situ crop productivity. We found that relatively higher SQI can be obtained with ecotoxicological indicators than that without them, and soil quality indexing with ecotoxicological indicators showed high correlations with in situ crop productivity in paddy and upland soil plots.
Analysis Of Violations Construction Of Buildings In Normative Law
Authors: Simamora Melki Suheri
Published: April 2023

Spatial planning is one of the challenges faced by the government City due to violations of the construction of buildings by the community that not only harm the surrounding community but also disrupt the spatial order that has been planned by the city government. This study discusses several law enforcement regulations violation of the construction of buildings in the city of Semarang by using the method empirical juridical research and statute approach method conducted by reviewing legislation and interviews with the Department related to the purpose that people understand urban planning and the consequences if breaking.
Mammogram Image to Detect Breast Cancer Using K-Means Clustering Algorithm
Authors: Gopinathan B , Naveena M , Shreyas M , Charan Rohith D
Published: April 2023

Breast cancer is the uncontrolled proliferation of a group of cells in the breast and is the second leading cause of death for women in the world. The disease can be cured if detected in the early stages. A lot of research has been done to correctly detect the tumor, but a 100% accurate method has not been found. Research on breast cancer detection using digital image processing is not new, but many new approaches are being considered in this field to accurately predict the tumor area. The current approach consists of detecting the tumor area visually and also finding out in which area the tumor is most concentrated. CC and MLO dualview mammographic screening images are widely used in the diagnostic process. This project presents a method for detecting a tumor area and classifying a normal and oncological patient. Preprocessing operations are performed on the input mammographic image and unwanted parts are removed from the image. Tumor regions are segmented from the image using a morphological operation and are highlighted on the original mammographic image. If the image on the mammogram is normal, it means that the patient is healthy. This work mainly focuses on finding the best algorithms for detecting tumors present in the breast. A number of algorithms were used in the proposed work, but the most suitable for cancer detection is the combination of K-Means clustering algorithm. K-Means classification accuracy is 95% accurate output will be predicted. Keywords: Image Processing, Breast Cancer, K-Means clustering, Dilation, Closing, Edge Detection, Mammography screening images
Habilidades blandas en la gestión de práctica docente y administrativa en Educación Superior: modalidad híbrida
Authors: Pinos Medrano Viviana Fabiola , Solis Muñoz Juan Bautista , Salamea Sánchez Jessica Lucía
Published: April 2023

El propósito de la presente investigación es correlacionar las habilidades blandas de los estudiantes con la gestión de la práctica docente en la gerencia educativa aplicado a una institución educativa superior. Se considera que las habilidades blandas potencia las capacidades del estudiante y mejora la calidad de la gerencia educativa. La investigación es de tipo cuantitativa, transversal, no probabilística e intencional, correlacional. Se parte de un constructo donde la variable independiente X1 habilidades blandas y la variable dependiente la gestión de la práctica docente. El instrumento de medición fue validado por consenso de expertos, la consistencia interna del cuestionario se hizo con el coeficiente del Alpha de Cronbach para la escala general es de 0,777. Los resultados correlacionales muestran que la variable habilidades blandas se correlacionan en forma positiva y alta con la gestión de la práctica docente (0,551**) y es estadísticamente significativa menor al p-valor de 0.05. Se concluye que la gerencia educativa debe considerar en sus planes, programas y proyectos la asociación entre las habilidades blandas y la gestión de la práctica docente para tener mejores y mayores resultados en el aseguramiento de la calidad de la educación superior.
On the issue of satisfying victims’ claims when imposing punishment in the form of imprisonment on the perpetrator
Authors: Миронов А.В.
Published: April 2023

В статье анализируется законодательство и правоприменительная практика в сфере реализации исковых требований потерпевших, которые не были применены на досудебной и судебной стадиях в рамках гражданского иска в уголовном деле. Рассмотрены возможности по трудовому устройству осужденных к лишению свободы как источнику средств для погашения исковых требований, а также перспективы реализации исковых требований после освобождения из исправительного учреждения с учетом развития и корректировки норм УК РФ, судебной практики в данной сфере и введения службы пробации в Российской Федерации.

The article analyzes legislation and law enforcement practice in the field of satisfying victims’ claims, which were not applied at pre-trial and judicial stages in the framework of a civil claim in a criminal case. It considers possible employment of persons sentenced to imprisonment as a source of funds for the repayment of claims, as well as prospects for satisfying claims after release from a correctional facility, taking into account the development and amendment of norms of the Criminal Code of the Russian Federation, judicial practice in this area and the introduction of probation service in the Russian Federation.
Calidad de atención y satisfacción del usuario de consulta externa en un hospital público del Perú
Authors: Arévalo-Marcos Rodolfo A.
Published: April 2023

Objetivo. Determinar la relación que existe entre la calidad de atención y la satisfacción del usuario de la consulta externa del Hospital Nacional Daniel Alcides Carrión, en Callao (Perú). Métodos. El estudio tuvo enfoque cuantitativo, fue de tipo observacional y trasversal. La muestra no probabilística estuvo compuesta por 100 usuarios. Se aplicó dos escalas para medir la calidad de atención y la satisfacción del usuario que fueron previamente validadas y fiabilizadas. En el análisis inferencial se aplicó la prueba rho de Spearman. Resultados. El 51 % percibió que la calidad de atención era de nivel regular, frente a un 39 % que consideró que la calidad de atención era buena. Por otro lado, se encontró que el 39 % de la muestra estaba medianamente satisfecho con el servicio y el 29 % estaba satisfecho, pero se encontró también que el 32 % de la muestra estaba insatisfecho con el servicio brindado por el personal de salud. Conclusión. Existe una relación directa entre la calidad de atención y la satisfacción del usuario de la consulta externa del Hospital Nacional Daniel Alcides Carrión (rho de Spearman de 0,626 significante al 0,001).
The Effect of Birth Ball Use on Labor Progress: A Literature Review
Authors: Desyanti Harwin Holilah , Widad Shofiatul
Published: April 2023

The problem of the high number of MMR and IMR in Indonesia is that there are still many prolonged labor which is one of the several causes of maternal and newborn mortality. One of the therapies that can be done to prevent this is the use of Birth balls. Birth balls can prevent maternal fatigue caused by long duration of labor. The purpose of this articel was to provide an overview of the effect of birth ball exercises on the progress of the first stage of labor. This research used the Literature Review method. The sampling method used purposive sampling technique by selecting articles with appropriate topics. The results of the study through the stages of identification, screening, eligibility and include, found that there was an effect of giving birth ball exercises therapy in accelerating the progress of labor in maternity mothers. This is because the birth ball exercise is able to relieve pressure and increase the area of the pelvis, encourage the baby's head to descend, help uterine contractions more effectively, accelerate cervical dilation, and help to relax the ligaments in the pelvis.
Model Cakar Sebagai Media Edukasi Terhadap Peningkatan Perilaku Remaja dalam Pencegahan Karang Gigi
Authors: Fatman Siti Adlinah , Sunarjo Lanny , Fatmasari Diyah , Kusno Kusno
Published: April 2023

Based on RISKESDAS data for 2018, 57.6% of people in Indonesia have dental and oral health problems. Meanwhile, in the province of Central Java, dental and oral health problems reached 56.66% and only 9.02% received treatment. In the city of Semarang, dental and oral health problems reached 48.38% and only 14.22% received treatment. Dental health problems in adolescents are not much different from dental and oral health problems in children and adults. There are many ways that can be done to overcome these problems including the use of multimedia as an educational medium. The use of Augmented Reality has proven effective in increasing student learning interest. Proving the effectiveness of applying the CAKAR model (Augmented Reality Tartar Disc) as an educational medium in increasing changes in adolescent behavior in preventing tartar. The method used is Research and Development with a Quasy experiment Pretest-Posttest group design research design. The "CAKAR" model is appropriate as a media for dental health education with expert validation results of 82% and a p-value of 0.008, as well as the results of the delta test stating that its application is effective in increasing intervention knowledge (Δ5.03), control (Δ0.63), intervention attitude (Δ6.9). ) control (Δ0.16), intervention measures (Δ2.63) control (Δ0.43), and decreased OHIS intervention score (Δ0.42) control (Δ0.18). The application of "CAKAR" is appropriate and effective in changing adolescent behavior in preventing tartar.
The Influence of Emotional Intelligence, Nurse Loyalty, Leadership Style, Intervention of Motivational Variables in Hospital
Authors: Rahman Sarah Ainar , Supriyantoro Supriyantoro , Anindita Rina
Published: April 2023

Employees are human resources which are the most important assets to provide excellence to drive the dynamics of an organization or company. Loyal employees can be a very valuable asset for the organization because they can help get as much profit as possible for the organization. The purpose of this study was to analyze the influence of leadership, Emotion intelligence on employee loyalty with motivation as an intervening variable on nurses at the South Sumatra Type C Hospital. This research is a quantitative research, data collection was carried out using a questionnaire instrument. The number of samples determined is 120 employees. The sampling technique was done by purposive sampling. The analytical method using the partial least squares approach - structural equation modeling (SEM-PLS) with the SMART PLS program was used for data analysis. The results showed that leadership style had a positive and significant effect on employee motivation and loyalty, Emotion intelligence had a positive and significant effect on employee motivation and loyalty, and work motivation had a positive and significant effect on employee loyalty at the South Sumatra Type C Hospital.
Breadfruit Flour, Food to Lower Blood Sugar Levels in Mice Model Diabetes Mellitus
Authors: Kaihena Martha , Ukratalo Abdul Mahid , Nindatu Maria , Birahy Deford Christy
Published: April 2023

Consumption of foods with high amylose content (>25%) as well as a low glycemic index (<55) is able to improve the insulin sensitivity of people with diabetes mellitus. Breadfruit has in about 23-60 which means that breadfruit is safe to consume. The purpose of this research is to find out the levels of reduced sugar, amylose, and blood sugar levels mice after being fed breadfruit flour. This research used a Complete Randomized Design using 5 treatments namely normal control group (KN), negative control (K-), positive control (K+), STZ + breadfruit flour dose 5 g (P1) and STZ + breadfruit flour dose 10 g (P2). Breadfruit is taken and then processed into breadfruit flour, after which testing of reduced sugar content and amylose breadfruit flour. Before treatment, all mice were measured for initial glucose levels. After that in groups K (-), K (+), P1, and P2 injected STZ on days 1, 2, and 3. After 3 days, the blood glucose level (post-STZ) was measured again, then compared to the blood glucose level on the first day before being given STZ. If there is an increase in blood glucose levels of mice that is to ±128 mg / dL then mencit is considered to be diabetic. Then in group K (+) drug given Metformin, P1 and P2 were fed breadfruit flour with a predetermined dose for 7 days. The results showed that the sugar content of reduced breadfruit was cut by 3.26%. While the level of amylose in breadfruit flour is 19.3%. Breadfruit flour can also lower the sugar content of mice.
Kualitas Pelayanan Pendaftaran Rawat Jalan Pasien Jaminan Kesehatan Nasional di Rumah Sakit Royal Progress
Authors: Susanti Melly , Hartono Risky Kusuma , Ningsih Desy Kartika
Published: April 2023

The hospital is one of the health facilities where it organizes health efforts that deal with medical problems for the recovery and maintenance of health needed for its users. It is necessary to know the quality of outpatient registration services for National Health Insurance patients. To determine the effect of Input (HR, Technology Facilities) and processes (Professional and expertise, attitude, Behavior, Situation Control, Problem Solving, Ease of achievement and adjustment, Reliability and trust) that will produce quality in outpatient registration services at Royal Hospital Progress especially for patients using the National Health Insurance. sampling non-probability sampling. The sampling technique was purposive sampling. Human Resources, there is a shortage of service officers, in terms of internet speed technology and the lack of bridging of SIMRS with the JKN web is one of the factors that affect quality in terms of speed of service, in terms of the process where the ease of achieving and adjusting services has not been achieved because of the patient's waiting time when registering until data verification gets SEP still above 15 minutes. In other factors, namely Facilities, Professional and expertise, Attitude, Behavior, Control of the situation, Problem solving, Reliability and trust showed positive results. The quality of Outpatient Registration Services at the Royal Progress hospital illustrates good and satisfying service for patients including a very adequate waiting room, disabled toilets and elevators which are very much needed for patients. Registration staff are very professional in doing their jobs. Also described in the attitude of friendly and always smiling officers in receiving patients who come for treatment at Royal Progress Hospital, the very high empathy given by registration officers to patients who need help and the fast response received by patients when patients experience difficulties in administration This is what makes Royal Progress Hospital provide excellent service even though there is still a shortage of both human resources and networks, but in general the services provided to JKN patients are quite good
Optimalisasi Model Pembelajaran Berbasis Proyek (Project Based Learning) untuk Meningkatkan Keterampilan Menulis Karya Ilmiah
Authors: Pontjowulan Pontjowulan
Published: April 2023

This study aims to determine the increase in students' writing skills through project-based learning (Project Based Learning). The subjects of this study were students of class XI BDP-2 at SMK Negeri 9 Samarinda for the 2021/2022 academic year, a total of 33 students. Writing a class action research report (CAR) uses a descriptive method. Collection of information to determine students' writing ability by using tests. The technique used is face-to-face learning in class through several stages, namely: (1) the teacher prepares the Lesson Plan (RPP), (2) the teacher prepares learning materials and assignments, (3) students study the material, (4) the teacher monitors activities teaching and learning in class, (5) the teacher provides feedback on learning and assignments that have been done by students. The use of project-based learning models (Project Based Learning) can improve students' ability to write scientific work texts. The average value of student learning outcomes after using the project-based learning model (Project Based Learning) is 69.70%, an increase of 30.31% compared to the mastery learning before using the project-based learning model (Project Based Learning) which reached 39.39%. on scientific work text material.
STUDY OF STRENGTH CHARACTERISTICS AND RADIATION-PROTECTIVE PROPERTIES OF POLYSTYRENE TUNGSTEN COMPOSITE MATERIALS
Authors: Prokhorenko E.M. , Lytvynenko V.V. , Zakharchenko A.A. , Khazhmuradov M.A. , Prokhorenko T.G.
Published: April 2023

Samples of composite materials are made of polystyrene, which is reinforced with dispersed aluminum. The radiation protective additive was powdered tungsten or powdered steel. The tensile strength, for these samples of composites, was investigated. The tensile strength value was obtained at various temperatures. It has been found that
the ultimate strength of composites increases with an increase in the metal component. Composites with different component compositions were studied. The relative attenuation of the absorbed dose of gamma radiation by these composite materials has been calculated. Composites were with different mass composition. The code of Geant4 v
4.9.6p03 applied for calculations. It is got, that experimental results coincide with calculation results.
EMPIRICAL PREDICTED RESIDUAL LIFE OF THE BASE METAL OF MCP OF WWER-1000 REACTORS IN OPERATION
Authors: Gozhenko S.V.
Published: April 2023

The comprehensive analysis of the results of research by direct methods of BM of MCP of the South-Ukraine NPP after 100,000 and 200,000 h of operation was carried out. In BM with a fine-grained initial structure, the first stage of the aging process, accompanied by metal strengthening, is completed during the first 100,000 h of MCP operation; then the second stage begins, accompanied by decreasing of metal strength. In BM with a coarsegrained initial structure, the first stage of the aging process lasts more than 200,000 h of operation. The predicted residual resource of MCP is determined by the resource of BM with a fine-grained initial structure. The critical regulatory property at the first stage of the aging process of BM is relative elongation, at the second stage – the strength limit.
Profil Status Gizi Anak Sekolah Dasar Kabupaten Banyuwangi
Authors: Novia Prawita Murti  , Danang Ari Santoso  , Puji Setyaningsih  , Moh. Agung Setiabudi
Published: April 2023

Tujuan penelitian ini untuk menggambarkan status gizi anak sekolah dasar di Kabupaten Banyuwangi. Jenis penelitian deskriptif dengan pendekatan studi kasus. Penentuan sampel menggunakan cluster sampling dengan membuat kelas berdasarkan wilayah. Sampel pada penelitian ini adalah SDN 1 Yosomulyo, SDN 2 Tukang Kayu, dan SDN 1 Bangsring. Instrumen yang digunakan adalah perhitungan Indeks Massa Tubuh (IMT) dengan pendekatan analisi prosentase. Hasil penelitian menggambarkan status gizi anak sekolah dasar Kabupaten Banyuwangi dengan kategori sangat kurus 5,31%, kurus 4,13%, normal 84,95%, dan gemuk 5,61%. Dengan kata lain dapat disimpulkan status gizi anak sekolah dasar kabupaten Banyuwangi dalam kategori normal.
Rancang Bangun Website Media Pembelajaran Di Smp Katolik Santa Maria Palangkaraya Dengan Php Mysql
Authors: Widiatry Widiatry , Kristina Dhea
Published: April 2023

Santa Maria Catholic Middle School is a junior high school which is located at Jalan Cilik Riwut, Jekan Raya District, Palangka Raya City. It does not yet have a website like most schools in Palangkaraya City. So this Junior High School does not introduce its school to the wider community. Not only that, this junior high school also still uses the books offered by the teacher for its learning. Based on this background, "Design and Build a Learning Media Website at Santa Maria Palangkaraya Catholic Middle School with PHP MySQL", in order to support the student learning process. The methodology used in designing and building this website is the waterfall method, namely analysis, design, implementation and testing. The design design uses Data Flow Diagrams (DFD), Flowcharts, ERD, coding using PHP and MySQL and Black Box Testing as a software testing method. From the results of this test it can be concluded that "Designing Learning Media Websites at Santa Palangkaraya Catholic Middle School with PHP MySQL" was created with the aim of facilitating student learning.
Implementasi Modul Website Kepelangganan Manager Support Pada Sistem Informasi Penyedia Layanan Internet Rumah Menggunakan Third Party API
Authors: Munthe Samuel Septa , Sari Nova Noor Kamala , Lestari Ariesta
Published: April 2023

In the current development of the use of internet services, internet service providers company provides internet services that can be connected to customer’s houses. PT. XYZ is an internet service provider company that operates in the city of Blitar, East Java. The customer of support manager registration process for internet services on this client still does not have an online system so that registration is still done manually by the support manager to be able to integrate its customers with the network provided by the company. Therefore, this registration process on PT. XYZ needs to be converted into an online subscription information system to simplify the subscription registration process and so on.  This system module was developed using evolutionary prototyping methodology, starting from the quick design stage by analyzing requirements and designing the system quickly so that it can go directly to the prototype build process. The process of building a prototype is carried out by implementing the results of the system design, then followed by user evaluation to get feedback on the prototype that was built. The prototype refining stage is for stabilization on the prototype that has been made previously and there is a test of the system using the black box testing method.  After several trials, and results of the trials carried out, it can be concluded that the system is running well and can be used as a Support Manager Subscription Module on the Home Internet Service Provider Information System in Blitar City. By implementing third party

Application Programming Interface (API), the resulting subscription web module can display maps, bank account mutations, and WhatsApp notifications to assist the registration and payment process.
Rancangan Bangun Sistem Informasi Pengelolaan Penerimaan Peserta Didik Baru di SMA Negeri 1 Tamiang Layang Berbasis Website
Authors: Milenia Tiara Sari , Nugrahaningsih Nahumi
Published: April 2023

SMA Negeri 1 Tamiang Layang is one of the high schools located in East Barito Regency. The purpose of this research is to build an Information System Website for the Management of New Student Admissions at SMA Negeri 1 Tamiang Layang. The system development method used is the Waterfall model, starting from analysis, design, implementation and testing. The design is using Data Flow Diagrams (DFD) using context diagrams, Level 0 and Level 1 DFDs and Entity Relationship Diagrams (ERD), PHP programming language and MySQL database. The result of the research is that a website for the Management of New Student Admission Management Information System at SMA Negeri 1 Tamiang Layang can be produced that can run and function properly.
Aplikasi Website Indeks Kepuasan Masyarakat (Studi Kasus: Kelurahan Panarung)
Authors: Priskila Ressa , Sari Nova Noor Kamala , Surana Yogi Andy Pratama
Published: April 2023

Service performance appraisal is now starting to become a benchmark for achieving quality service by evaluating every service and piece of information provided. The provision of questionnaire sheets is currently considered less effective in determining the satisfaction index of services due to storing data on questionnaire results and re-recording the results that have been filled in by the community. Therefore, this study aims to build a website to improve the work system with the aim of increasing the efficiency of the community satisfaction index. In designing the Community Satisfaction Index (IKM) Website, Panarung Village uses the waterfall method with stages: requirements definition, system and software design, implementation and unit testing, integration and system testing, operation and maintenance. This website has been tested with black box testing, and the results show that the features on the website can run well. The Panarung Village Community Satisfaction Index (IKM) website can be used as evaluation material for the performance of services in the Pahandut sub-district and also as a means of information such as news data, graphs, survey results, and criticism suggestions.
Euglycemic Diabetic Ketoacidosis in Patients Taking Sodium-Glucose Co-Transporter 2 (SGLT2) Inhibitors: Review of the Literature
Authors:   Instituto de Salud del Estado de México. Calixtlahuaca, Toluca, México., Sanchez Dafne Sherlyn Moreno , Larios Jiany Froylan De Paz ,   Instituto de Salud del Estado de México. Calixtlahuaca, Toluca, México., Salas Jorge Manuel García ,   Instituto de salud del Estado de México, Centro Especializado de Atención Primaria a la Salud San Juan de las Huertas, Morelos, México., Salazar Jorge Armando Duarte ,   Jurisdicción IX Ameca; Centro de Salud. San Marcos, Jalisco, México., García Guadalupe Linares ,   Instituto de salud del Estado de México, Centro Especializado de Atención Primaria a la Salud San Juan de las Huertas, Morelos, México.
Published: April 2023

This paper provides an overview of euglycemic diabetic ketoacidosis (euDKA) associated with the use of sodium-glucose co-transporter 2 (SGLT2) inhibitors. euDKA is a rare but potentially life-threatening complication that can occur in patients taking SGLT2 inhibitors, and its clinical presentation differs from traditional diabetic ketoacidosis. This paper discusses the epidemiology, pathophysiology, clinical manifestations, diagnosis, and treatment of euDKA. Prompt recognition and appropriate treatment are critical to prevent morbidity and mortality. Healthcare providers should be aware of the potential risk of euDKA in patients taking SGLT2 inhibitors and educate them on the signs and symptoms of this serious complication. Further research is needed to better understand the pathophysiology of euDKA and identify strategies for its prevention and treatment.
FORIAS: MÉTODOS DE AVALIAÇÃO OBJETIVOS E SUBJETIVOS
Authors: Trentin Sonoda Rodrigo , Lobianco de Moura Karen , Matilde dos Santos Erica
Published: April 2023

O uso exacerbado do sistema visual em sua sincinética, promove diversos distúrbios e sintomas no usuário de telas e excesso de atividades escolares, na atualidade. A preocupação com fatores estéticos do passado, em casos de estrabismo, atualmente são superadas por problemas de neurodesenvolvimento e aprendizagem, promovidos pelos excessos visuais. Observa-se na literatura, os malefícios do excesso de exposição à écrans e a astenopia digital. Desvios latentes são notados e podem provocar embaçamento da visão, fadiga da musculatura ocular, desinteresse e falta de concentração à leitura. A fadiga percebida nos músculos extrínsecos oculares é uma das responsáveis pelas forias, esses desvios provocam diversos efeitos neusosensoriais indesejados. As técnicas de aferição são diversas e com variações. Maddox, Torrington e Howell serão foco de discussão que terá como objetivo mensurar forias e sua compensação, evitando a sintomatologia. Através de revisão de estudos publicados e artigos, demonstra-se a importância da propedêutica e condutas optométricas frente a desvios.
Cloning and Expression of SARS COV-2 Surface Protein and its Use in Detecting Corona Viral Infections
Authors: Abu-Helu Rasmi
Published: April 2023

The main aim of this study was to develop indirect enzyme linked immune sorbent assay based on the use of bacterial cloned SARS CoV-2 spike protein as a cheap and continuously available source of antigen. This test was proved to be useful for a quantitative measurement and evaluation of antibody immune response among SARS-CoV-2 infected individuals. Standard cloning procedures had been used in cloning two different segments of the spike gene and its expression. The size of the two
cloned segments were of 700 base pair and of 500 base pair, which were named clone 8 and clone 105, respectively. These DNA segments were cloned in pET28a plasmid and then expressed in Bl21 E. coli. Different serum samples were tested from: current, previous infection, vaccinated and non-vaccinated patients using the amplified expressed proteins in enzyme linked immune sorbent assay. The expressed proteins from each clone were responded with varying degrees of sensitivity against COVID-19 positive human sera, and we attempted to validate which of the two recombinant proteins is the best to be used in Corona IgG and IgM antibody detection. Based on the results of indirect enzyme linked immunoassay, most of the tested samples had greater antibody titers with clone 8, which was found to have a higher similarity (99% resemblance) to the severe acute respiratory syndrome coronavirus 2 surface protein using BLAST search. We recommend clone 8 with high potential to be used for large-scale screening for COVID-19 outbreak; nevertheless, it requires greater sensitivity and specificity validation
A Systematic Review on Training and Development in the Hotel Industry
Authors: Barreto Nigel , Mayya Sureshramana
Published: April 2023

Purpose: Training and Development is much required in the realm of business and executives today, yet there is a blatant disregard of something very similar. As the neighbourliness area and inn industry went through so many high and low points and threw about, adhering to an establishment turns out to be increasingly required; how execution is assessed and checked on has gone through many moves and changes. The motivation behind this study endeavours to grasp the available resources, Preparing and Improvement has on the presentation of representatives extraordinarily inside the friendliness and inn industry centring and grovelling more towards the Indian relevant perspective through an efficient literature review.
Design: The survey assessed the writing on different parts of Preparing and Improvement in the Accommodation and Inn business in India that were distributed somewhere in the range of 1990 and 2022, and it additionally utilized an ABCD examination to assess the effect of Preparing and Advancement and its Effect on Execution and result inside a similar area.
Findings: Cordiality and Hospitality is one of the country's most sort out organizations; modified organizations give off an impression of being procuring and more noteworthy pervasiveness. To achieve these benchmarks of execution, genuine readiness and improvement of such points and kinds of organizations aren’t simply significantly crucial yet sort after in this field, regardless of the way that there have been past assessments coordinated inside this industry, there are holes which ought to be watched out for which can achieve a lot of investigation and answers being looked at subsequently will assist the expert in focusing in the focus on basic districts that with requiring a more careful investigation.
Practical implication: The examination this paper will expose is a previous point of view and perspective on the preparation and improvement rehearses in India overall furthermore, with unique reference to the friendliness and lodging industry, this thus will help specialists in pinpointing and zeroing in on the main angles that require future examination and study
Value: Preparing and Advancement is a fundamental perspective and part of any conspicuous Industry. Albeit a ton of study and survey has been directed inside this area, evaluating how the preparation and improvement developed is a special perspective not read time after time. The creator has endeavoured to investigate training and development practices in the hospitality industry, as little too uncommon exploration and study has been conducted in this field. Researchers and specialists would view this paper as a need as tended to through the article's present status and existing hole in the writing of preparing and improvement in the friendliness area.
Paper Type: Review paper
A EDUCAÇÃO ÉTNICO-RACIAL NA ESCOLA: EXPERIÊNCIAS DE JOVENS DO QUILOMBO CHÁCARA DAS ROSAS – CANOAS/RS
Authors: Malonn Carina , Fritsch Rosangela , Pasinato Darciel
Published: April 2023

O estudo trata das relações étnico-raciais na   trajetória escolar de jovens quilombolas do Quilombo Chácara das Rosas, no município de Canoas no estado do Rio Grande do Sul, Brasil. Trata-se de uma pesquisa qualitativa de natureza exploratória ocorrida entre os anos 2020 e 2021. Por meio da análise de conteúdo de entrevistas compreensivas e da análise documental de políticas educacionais sobre educação étnico-racial objetivamos compreender como as relações étnico-raciais são percebidas e significadas por quatro jovens quilombolas em suas trajetórias escolares no Ensino Fundamental. Sustenta-se teoricamente no campo das epistemologias do sul, políticas educacionais e no conceito de juventudes. Identificamos que a relevância da educação para as relações étnico-raciais é compreendida pelos jovens. No entanto, possuem contato pontual com a temática na escola, o que os faz procurar conhecimentos sobre suas origens culturais por meio da oralidade, em conversas realizadas com familiares no interior do Quilombo. Os conteúdos, ações e atividades relacionadas e educação das relações étnico-raciais são escassas nas escolas e influenciam na percepção de jovens negros sobre si e seus posicionamentos nos espaços coletivos.
CONHECIMENTO PRODUZIDO SOBRE AUTOAVALIAÇÃO NOS PROGRAMAS DE PÓS-GRADUAÇÃO BRASILEIROS
Authors: Mesquita Marcos Paulo , Lima Elizeth Gonzaga dos Santos , Leite Denise Balarine Cavalheiro
Published: April 2023

Este trabalho mapeia as pesquisas nos Programas Nacionais de Pós-Graduação (PNPG) de 2015 a 2020 que discutem a autoavaliação (AA), indicador de qualidade introduzido pela CAPES e já adotado no quadriênio iniciado no ano de 2021. Seguimos os procedimentos da pesquisa qualitativa com o foco em análises bibliográfica e documental ao tentar identificar práticas inovadoras de autoavaliação nos programas de pós-graduação (PPGs) do Brasil presentes nas teses e dissertações catalogadas no BTDC-CAPES. Encontramos 465.115 trabalhos publicados, entre os quais 888 versavam sobre a autoavaliação. Identificamos uma predominância de pesquisas de AA voltadas a cursos de graduação e os maiores esforços de pesquisa do tema em relação a pós-graduação estão nas teses de doutorado. Constatamos que poucos programas teriam implantado e implementado a autoavaliação anteriormente às exigências da quadrienal CAPES 2021-2024. Isso indicaria uma possível deficiência, uma fraqueza, na cultura do uso informado da AA nos PPGs, o que poderia vir a se tornar uma barreira à sua implantação. Esses desafios devem ser enfrentados para que os avanços da inclusão da AA no atual instrumento de avaliação da CAPES não percam sua intencionalidade e sucumbam ao burocratismo favorecendo a manutenção da cultura de avaliação existente pela inação e conformismo. Ainda e sem concluir, apresentamos reflexões críticas sobre a AA, notadamente, no que tange à inestimável contribuição aos PNPGs.