bluuebunny/crossref_metadata_2025 huggingface dataset:
Introducing technology in Cypriot primary classroom music lessons: ‘I learnt using things in music I didn’t know existed’
Authors: Konstantinou Chrysovalentini
Published: September 2016

This articles presents issues around the introduction and use of technology in primary music education with particular reference to a study set in Cyprus that looks at the change in teachers’ practices, thinking and concerns as they become more engaged with technology and use it more. It examines the availability and use of technology in music lessons, the development of creative thinking and teaching with technology and the elements that facilitate the introduction and use of technology in music lessons. The study examines the cases of ten primary music teachers in Cyprus and uses interviews, questionnaires, observations and teacher reflection. It was indicated that if encouraged and provided with the technology, education, support and training they need, teachers can overcome their hesitations and use technology in their lessons.
feature article: Are our malls safe? Race and neoliberal discourse in Ruben Östlund’s Play
Authors: Gullette Christian
Published: September 2016

This article argues that Swedish director Ruben Östlund’s much-debated film Play (2011) codes racial differentiation in discourses of neoliberal economic competitiveness, able-bodiedness and masculinity in order to negotiate anxiety over white economic privilege and futurity in the contemporary Swedish marketplace and society.
feature article: The Danish producer in an era of convergence and globalization: An interview with Meta Louise Foldager
Authors: Meir Christopher
Published: September 2016

Producers are seldom the focus of screen studies research, but this interview with Danish producer Meta Louise Foldager demonstrates just how useful these vital creators are to understanding the Scandinavian film and television industries, both of which currently find themselves in periods of rapid change. The interview focuses on three themes: the differing roles that the producer plays in film and television production; the state of the Danish film industry; and the burgeoning television drama industry in Denmark. Throughout these three sections, Foldager discusses how local and global forces are influencing her work and that of her colleagues in both industries.
Convex Hull Property and Exclosure Theorems
for H-Minimal Hypersurfaces in Carnot Groups
Authors: Montefalcone Francescopaolo
Published: September 2016

In this paper, we generalize to sub-Riemannian Carnot groups some classical results in the theory
of minimal submanifolds. Our main results are for step 2 Carnot groups. In this case, we will prove the
convex hull property and some “exclosure theorems” for H-minimal hypersurfaces of class C2 satisfying a
Hörmander-type condition.
Evaluation of the hypochromic erythrocyte and reticulocyte hemoglobin content provided by the Sysmex XE-5000 analyzer in diagnosis of iron deficiency erythropoiesis
Authors: Buttarello Mauro , Pajola Rachele , Novello Enrica , Mezzapelle Giacomo , Plebani Mario
Published: September 2016

Background:

Iron deficiency represents the most frequent cause of anemia. To diagnose iron deficiency some biochemical tests such as serum ferritin and the transferring saturation percent (TSAT%) are usually used. Recently, some hematological parameters such as mean reticulocyte hemoglobin content (CHr or Ret-He) and percentage of hypochromic RBCs (Hypo% or %Hypo-He) were proposed as alternative to biochemical tests. In this study, the analytic performance and the diagnostic efficiency of these two parameters provided by Sysmex XE5000 analyzer on iron deficiency patients with or without anemia (IDA and ID, respectively) were evaluated.

Methods:

One hundred and sixty-four healthy adults, 58 with IDA, 21 with iron depleted stores (ID), 23 with β-thalassemia trait, and 24 with non iron deficiency anemia were selected. The gold standard used to define iron deficiency was the coexistence of serum ferritin below 15 μg/L (12 in women) and TSAT <16%.

Results:

For %Hypo-He, the best cut-off value for both IDA and ID is 0.9% while for Ret-He is 30.6 pg. For both parameters the performance was better to diagnose IDA (AUC, 0.96 and 0.98) than ID (AUC, 0.93 and 0.95). The Ret-He behavior was always slightly better than that of %Hypo-He.

Conclusions:

The use of these two parameters is useful to detect iron deficiency conditions if the hemoglobin synthesis has already been compromised.
Spanish Preanalytical Quality Monitoring Program (SEQC), an overview of 12 years’ experience
Authors: Llopis María Antonia , Bauça Josep Miquel , Barba Nuria , Álvarez Virtudes , Ventura Montserrat , Ibarz Mercè , Gómez-Rioja Rubén , Marzana Itziar , Puente Juan Jose , Segovia Marta , Martinez Debora , Alsina María Jesús
Published: September 2016

Background:

Preanalytical variables, such as sample collection, handling and transport, may affect patient results. Preanalytical phase quality monitoring should be established in order to minimize laboratory errors and improve patient safety.

Methods:

A retrospective study (2001–2013) of the results obtained through the Spanish Society of Clinical Biochemistry and Molecular Pathology (SEQC) External quality assessment (preanalytical phase) was performed to summarize data regarding the main factors affecting preanalytical phase quality. Our aim was to compare data from 2006 to 2013 with a previously published manuscript assessing the 2001–2005 period.

Results:

A significant decrease in rejection rates was observed both for blood and urine samples. For serum samples, the most frequent rejection causes in the first period were non-received samples (37.5%), hemolysis (29.3%) and clotted samples (14.4%). Conversely, in the second period, hemolysis was the main rejection cause (36.2%), followed by non-received samples (34.5%) and clotted samples (11.1%). For urine samples, the main rejection cause overall was a non-received sample (up to 86.1% of cases in the second period, and 81.6% in the first). For blood samples with anticoagulant, the number of rejections also decreased. While plasma-citrate-ESR still showed the highest percentages of rejections (0.980% vs. 1.473%, p<0.001), the lowest corresponded to whole-blood EDTA (0.296% vs. 0.381%, p<0.001).

Conclusions:

For the majority of sample types, a decrease in preanalytical errors was confirmed. Improvements in organization, implementation of standardized procedures in the preanalytical phase, and participation in a Spanish external quality assessment scheme may have notably contributed to error reduction in this phase.
An extention of Nomizu’s Theorem
–A user’s guide–
Authors: Kasuya Hisashi
Published: September 2016

For a simply connected solvable Lie group G with a lattice Γ, the author constructed an explicit
finite-dimensional differential graded algebra A*Γ which computes the complex valued de Rham cohomology
H*(Γ\G, C) of the solvmanifold Γ\G. In this note, we give a quick introduction to the construction of such A*Γ including a simple proof of H*(A*Γ) ≅ H*(Γ\G, C).
The Evolution of Family Farms in Poland: Present Time and the Weight of the Past
Authors: Halamska Maria
Published: September 2016

The author provides an analysis of family farming in Poland during the period 1990-2012, with special attention towards the close links of ownership and the operation of the farm by family members. The weight of various factors is given close attention, including the historical context of the farm, current conditions, and future intentions for the farm.

The historical context acknowledges and stresses the importance of the late abolition of serfdom made by the partitioning powers, various agricultural reforms during the period 1919-1944, and the period 1948-1989 (when family farming was incorporated into a deficient centrally planned economy). This latter period saw family farms developing specific mechanisms of functioning, which can be seen two decades later. Analysis of the period 1990-2012 is based on data of the Central Statistical Office, the present study, and other published materials. The data series includes individual farms of more than 1 ha, based on family labour.

Separated are two sub-periods: the post-communist transformation period from the early 1990s, and the period 2002-2012. The latter almost coincides with the accession to the EU. In the first period, the article outlines the process of creating duality in Polish agriculture. This describes a group of family farms where the household strongly reacted to the market and became larger and modernised (professional – 1/3 of the total) and small, extensive and producing mainly for own consumption (semi-subsistence – 2/3). In the second period, the functioning and transformation of households taking place under the CAP are examined. Modernisation is primarily seen on the professional farm. Specific mechanisms can be seen that provide fairly stable functioning of semisubsistence farms, independent of the market, with non-farm incomes and agricultural social security. These farms resisted collectivisation and stopped and hindered modernisation during the communist period, and this post-communist transformation now requires a doubly controlled modernisation process.
Cultural and Regional Characterictics of Poverty Segregations
Authors: Siptár Dávid , Tésits Róbert , Alpek Levente
Published: September 2016

The process of segregation is a complex problem affecting both developed and developing states; it is influenced by territorial, historical, demographic and economic impacts. To solve this growing problem, we must know how it is influenced by different factors. In this case, we are able to describe the appropriate strategy. This study examines the characteristics of poverty’s regional segregation in Baranya county, Hungary. It describes and analyses the regularities and correlations at NUTS 3 level and compares four segregated living spaces in different areas of the county. Our theory postulates that segregation has different bases and different attributions according to geographical localisation. Due to the different and well-chosen research areas, this study is able to highlight these aforementioned regional differences and characteristics. According to the results, we create a standardisation system to form the basis for future studies and strategies. After all of the study analyses, the local conditions are categorised based on the previously established standardisation system. The results of this study can help manage the problems of marginalised social groups and territorial segregation and also create a strategy to handle them.
Borderlands of the Countryside. Dilemmas of the Quality of Life – Experience of the Polish Transformation
Authors: Dziubacka Krystyna , Pilarska Justyna
Published: September 2016

This study is a reflection on the quality of life of the countryside dwellers in the Polish–German borderland. It has been assumed that the assessment made is conditioned by the consequences of changes within the functioning of the state borders. Based on the findings from the research conducted in 1993 and 2010, an analysis of the changes of social reality in the place of the countryside dwellers’ residence was made, followed by an attempt to define determinants of the attitude of the countryside dwellers towards given social, economic and political aspects of the reality, as assessed and expressed by them.
α1-antitrypsin Deficiency: A Misfolded Secretory Protein Variant with Unique Effects on the Endoplasmic Reticulum
Authors: Perlmutter David H
Published: September 2016

In the classical form of α1-antitrypsin deficiency (ATD) a point mutation leads to accumulation of a misfolded secretory glycoprotein in the endoplasmic reticulum (ER) of liver cells and so ATD has come to be considered a prototypical ER storage disease . It is associated with two major types of clinical disorders, chronic obstructive pulmonary disease (COPD) by lossof- function mechanisms and hepatic cirrhosis and carcinogenesis by gain-of-function mechanisms. The lung disease predominantly results from proteolytic damage to the pulmonary connective tissue matrix because of reduced levels of protease inhibitor activity of α1-anitrypsin (AT) in the circulating blood and body fluids. Cigarette smoking is a powerful disease-promoting modifier but other modifiers are known to exist because variation in the lung disease phenotype is still found in smoking and non-smoking homozygotes. The liver disease is highly likely to be caused by the proteotoxic effects of intracellular misfolded protein accumulation and a high degree of variation in the hepatic phenotype among affected homozygotes has been hypothetically attributed to genetic and environmental modifiers that alter proteostasis responses. Liver biopsies of homozygotes show intrahepatocytic inclusions with dilation and expansion of the ER and recent studies of iPS-derived hepatocyte-like cells from individuals with ATD indicate that the changes in the ER directly vary with the hepatic phenotype i.e there is much lesser alteration in the ER in cells derived from homozygotes that do not have clinically significant liver disease. From a signaling perspective, studies in mammalian cell line and animal models expressing the classical α1-antitrypsin Z variant (ATZ) have found that ER signaling is perturbed in a relatively unique way with powerful activation of autophagy and the NFκB pathway but relatively limited, if any, UPR signaling. It is still not known how much these unique structural and functional changes and the variation among affected homozygotes relate to the tendency of this variant to polymerize and aggregate and/ or to the repertoire of proteostasis mechanisms that are activated.
Fourth power moment of coefficients of automorphic L-functions for
GL(m)
Authors: Jiang Yujiao , Lü Guangshi
Published: September 2016

Let π be a unitary cuspidal automorphic representation for

GL
m

⁢

(

𝔸
ℚ

)

{\mathrm{GL}_{m}(\mathbb{A}_{\mathbb{Q}})}

, and let

L
⁢

(
s
,
π
)

{L(s,\pi)}

be the automorphic L-function
attached to π, which has a Dirichlet series expression in the half-plane

ℜ
⁡
s

>
1

{\Re s>1}

, i.e.

L
⁢

(
s
,
π
)

=

∑

n
=
1

∞

λ
π

⁢

(
n
)

n
s

.

L(s,\pi)=\sum_{n=1}^{\infty}\frac{\lambda_{\pi}(n)}{n^{s}}.

In this paper we are interested in the upper bound of the fourth power moment of

λ
π

⁢

(
n
)

{\lambda_{\pi}(n)}

, i.e.

∑

n
≤
x

λ
π

⁢

(
n
)

4

{\sum_{n\leq x}\lambda_{\pi}(n)^{4}}

.
If

m
=
2

{m=2}

, we are able to consider the sixteenth power moment of

λ
π

⁢

(
n
)

{\lambda_{\pi}(n)}

.
As an application, we consider the lower bound of

∑

n
≤
x

|

λ
π

⁢

(
n
)

|

{\sum_{n\leq x}\lvert\lambda_{\pi}(n)\rvert}

, which improves previous results.
Halogenoheterocyclization of 2-(allylthio)quinolin-3-carbaldehyde and 2-(propargylthio)quinolin-3-carbaldehyde
Authors: Onysko Mykhailo , Filak Igor , Lendel Vasil
Published: September 2016

The reaction of 2-allyl(propargyl)thioquinolin-3-carbaldehyde with halogens (Br or I) results in formation of 1-halogenomethyl(halogenomethylidene)-4-formyl-1,2-dihydrothiazolo[3,2-a]-quinolinium trihalogenide. In the case of the propargylic derivative the process is stereoselective.
An unusually long electric wire in a urethra and bladder
Authors: Gupta Sandeep , Jain Pritesh , Pal Dilip Kumar , Banerjee Manju
Published: September 2016

Foreign bodies in the urethra and bladder are mostly due to self-insertion, iatrogenic insertion, migration from surrounding organs or through penetrating injuries. Self-insertion of a foreign body through the urethra is mostly related to sexual gratification, psychiatric conditions or to get relief from the intractable voiding symptoms. We present a case of a 17-year-old male who self-introduced an extremely long 120 cm electrical wire into his bladder for sexual gratification. The wire was removed by supra-pubic cystotomy to avoid urethral injuries.
Prevalence of physical inactivity and its association on oral conditions in adolescents
Authors: Viana Michelly , Amorim Renan , Pamato Saulo , Honório Heitor Marques , Pereira Jefferson Ricardo
Published: September 2016

Background:

The Brazilian population presents an ever-increasing number of sedentary people with poor oral health issues, including children and adolescents. Both physical inactivity and poor oral health have shown associations with various systemic diseases.

Objective:

The aim of this study was to verify the association between physical inactivity and oral health conditions.

Subjects:

Three hundred and fifty-three adolescents (mean age 13 and 17 years).

Methods:

An epidemiological cross-sectional study. Assessment of the presence of caries was made by using the decayed, missing, filled (DMF) index. Gingival bleeding and quality of oral hygiene were also examined to evaluate the oral conditions. The International Physical Activity Questionnaire (PAQ-C) was used to assess physical activity. The confidence parameter was set at p=0.05.

Results:

The results of this study showed that 74.3% were sedentary adolescents, the great majority of whom were girls (86.4%, p=0.001). There was a positive association between sedentary lifestyle and tooth decay (p=0.001), dental plaque (p=0.009), and time spent watching television (p=0.001).

Conclusion:

This study concluded that there was a positive association between physical inactivity and poor oral health.
Mining Dynamics: Using Data Mining Techniques to Analyze Multi-agent Learning
Authors: Sherief Abdallah
Published: September 2016

Analyzing the learning dynamics in multi-agent systems (MASs) has received growing attention in recent years. Theoretical analysis of the dynamics was only possible in simple domains and simple algorithms. When one or more of these restrictions do not apply, theoretical analysis becomes prohibitively difficult, and researchers rely on experimental analysis instead. In experimental analysis, researchers have used some global performance metric(s) as a rough approximation to the internal dynamics of the adaptive MAS. For example, if the overall payoff improved over time and eventually appeared to stabilize, then the learning dynamics were assumed to be stable as well. In this paper, we promote a middle ground between the thorough theoretical analysis and the high-level experimental analysis. We introduce the concept of mining dynamics and propose data-mining-based methodologies to analyze multi-agent learning dynamics. Using our methodologies, researchers can identify clusters of learning parameter values that lead to similar performance, and discover frequent sequences in agent dynamics. We verify the potential of our approach using the well-known iterated prisoner’s dilemma (with multiple states) domain.
Relationship between 25(OH)D levels and circulating lipids in African American adolescents
Authors: Sriram Swetha , Croghan Ivana , Lteif Aida , Donelan-Dunlap Bonnie , Li Zhuo , Kumar Seema
Published: September 2016

Background:

Vitamin D deficiency is commonly seen among African American adolescents. Lipid levels during childhood are excellent predictors of adult dyslipidemia and atherosclerosis. There is a paucity of data on the relationship between 25 hydroxy vitamin D [25(OH)D] levels and lipids among African American adolescents. The objective of this study was to determine if there is an association between 25(OH)D levels and circulating lipids in African American adolescents residing in midwestern United States.

Methods:

African American adolescents residing in Rochester, MN (latitude 44°N), USA, underwent measurements of 25(OH)D and lipids following overnight fast. Pearson’s correlation test, linear regression model and scatter plots were used to explore the association between 25(OH)D levels and lipids.

Results:

25(OH)D levels <30 ng/mL were seen in 21/24 (87%) of the subjects. 25(OH)D levels were inversely correlated with total cholesterol (r=–0.42; p=0.040) and with non-high-density lipoprotein (non-HDL) cholesterol (r=–0.42; p=0.040 ). These associations remained statistically significant after adjustment for age, gender and adiposity. In the multivariate linear regression model, and after adjusting for BMI Z-score, each 1 ng/mL increase in 25(OH)D was associated with a decrease in total cholesterol of 1.38 mg/dL (95% CI: –2.63, –0.14, p=0.030) and with a decrease in non-HDL cholesterol of 1.14 mg/dL (95% CI: –2.09, –0.18, p=0.020).

Conclusions:

25(OH)D levels were inversely correlated with total cholesterol and non-HDL cholesterol levels in African American adolescents residing in midwestern United States. Further studies with larger sample sizes are needed to determine if low vitamin D status in African American adolescents is a potential modifiable risk factor for cardiovascular disease.
Ethnicity and incidence of congenital hypothyroidism in the capital of Macedonia
Authors: Anastasovska Violeta , Kocova Mirjana
Published: September 2016

Background:

Congenital hypothyroidism (CH) is a common and preventable cause of intellectual disability for which early diagnosis is difficult without newborn screening. Genetic and environmental factors, race, ethnicity, sex, and pregnancy outcomes were noted as risk factors. In the study we aimed to determine the incidence of CH among different ethnic groups in the capital of Macedoina – a multiethnic city.

Methods:

A 14-year retrospective cohort analysis was performed on 121,507 newborns in the capital of Macedonia, Skopje, screened for whole-blood thyroid-stimulating hormone (TSH), in dry blood spots collected 48–72 h after birth, during the period 2002–2015. A TSH value of 15 mIU/L was used as cutoff point until 2010 and 10 mIU/L thereafter.

Results:

Primary CH was detected in 46 newborns (female to male ratio 1.3) with overall incidence of 3.8/10,000 (1/2641). The incidence of primary CH was significantly increased after lowering the TSH cutoff value (p=0.038), primarily due to detected neonates with transient CH for this period. Ethnic differences in the incidence of primary CH were detected. CH incidence among Roma neonates (6.7/10,000) was significantly higher (p<0.05) than the incidence detected in Macedonians (3.9/10,000) or Albanians (3.7/10,000).

Conclusions:

Increased incidence of CH in Roma newborns was detected as compared to other ethnicities in the capital of Macedonia. Further analysis of factors in direct interrelationship with the increased CH incidence in Roma newborns, as well as elucidation of impact of the CH incidence in this ethnicity on the overall incidence in Skopje, is warranted.
Current status of non-invasive prenatal testing (NIPT): genetic counseling, dominant methods and overall performance
Authors: Harasim Thomas , Rost Imma , Klein Hanns-Georg
Published: September 2016

The introduction of non-invasive prenatal testing (NIPT) into prenatal care represents a paradigm shift. With the absence of any intervention risk in contrast to invasive diagnostic procedures, NIPT has been widely adopted for the detection of fetal trisomy 13, 18 and 21. Additionally, fetal sex chromosome aneuploidy testing and sex determination are available, but can be compromised by both, medical and legal factors. Available validation studies were predominantly based on patients with a high a priori aneuploidy risk, determined by trimester screening or invasive diagnostics. In this review, we discuss the interpretation of NIPT results in context of patient specific risk constellations, the available performance data and dominant methodical approaches of NIPT including necessary content of genetic counseling.
Redetermination of the crystal structure of potassium lithium molybdate monohydrate, KLiMoO4·H2O
Authors: Park Garam , Oh In-Hwan , Kyeong Yu Su , Park Hyun-Min , Kim Ho-Sung
Published: September 2016

H2KLiMoO5, orthorhombic, Pbca (no. 61), a = 10.606(1) Å, b = 7.742(1) Å, c = 12.845(2) Å, V = 1054.8(2) Å3, Z = 8, R
gt(F) = 0.0333, wR
ref(F
2) = 0.0749, T = 298(2) K.
A technical study to economize the amount of zinc used in the production of radiogallium
Authors: Kandil Shaban A. , Al-Abyad Mogahed , Szűcs Zoltan
Published: September 2016

For the production of radiogallium, the targets were prepared in two forms, namely, electroplated metal and pressed oxide. The target holder was selected from Cu-metal as a circular disk. The experimental yields of 66,67,68Ga produced from both irradiated natZnO and zinc metal targets are given and compared with the estimated yields as well as with the previously reported values. The ZnO target developed in this work appears to be more convenient and economical for local production of short-lived radiogallium, e.g. 66Ga and 68Ga.
Chemometrical analysis of fingerprints for the detection of counterfeit and falsified medicines
Authors: Custers Deborah , Courselle Patricia , Apers Sandra , Deconinck Eric
Published: September 2016

Counterfeit medicines pose a major threat to public health worldwide. These pharmaceuticals are mostly manufactured without respecting Good Manufacturing Practices. Moreover, they are not subjected to any form of quality control, and therefore their safety, efficacy, and quality cannot be guaranteed. Extensive research on counterfeit medicines has already been performed and published in literature. This review aims at providing an updated overview of the use of fingerprints and subsequent multivariate (chemometrical) data analysis in the field of counterfeit medicine detection. Fingerprinting could be a useful tool in the analysis of counterfeit medicines because it generates a holistic view of a sample, rather than focusing on specific and predefined characteristics, such as identification and quantification of present active pharmaceutical ingredients. This review first provides an introduction into the counterfeiting problem. Next, the concept of fingerprinting and the basic principles of chemometrics are explained, followed by a description of the successful application of fingerprints in the field of Pharmacognosy. The last part of this review provides an overview describing the use of fingerprints in counterfeit medicine research.
Cinacalcet versus Parathyroidectomy in the Treatment of Secondary Hyperparathyroidism Post Renal Transplantation
Authors: Soliman Amin R. , Maamoun Hoda A. , Soliman Mahmoud A. , Darwish Hatem , Elbanna Esam
Published: September 2016

Background. Persistent hyperparathyroidism (HPT) with hypercalcemia is prevalent after transplant and is considered a risk factor for progressive bone loss and fractures and vascular calcification, as well as the development of tubulointerstitial calcifications of renal allografts and graft dysfunction. The subtotal parathyroidectomy is the standard treatment, although currently it has been replaced by the calcimimetic cinacalcet.

Aim. The hypothesis of this study is that subtotal parathyroidectomy is superior to cinacalcet for treatment of persistent secondary parathyroidectomy post renal transplant, with minimal morbidity and significantly it reduces the cost of treatment after transplantation.

Methods. We report our long-term clinical experience with either cinacalcet or parathyroidectomy in 59 kidney transplant recipients with hyperparathyroidism. Group one included medical treatment with cinacalcet and had 45 patients while parathyroidectomy patients (group 2) were 16 patients with two of them excluded because of surgical failure.

Results. No difference was found between groups for any parameter. A greater short-term change of calcium and phosphorus homeostasis obtained by surgery than by cinacalcet, and in long term change, no significant difference between the two groups.

Conclusions: The main findings of this study are that correction of severe hyperparathyroidism was similar in both surgical and cinacalcet groups with the absence of a difference of long-term serum iPTH 1-84 levels between the two groups.
Optimization of multi-sandwich-panel composite structures for minimum weight with strength and buckling considerations
Authors: Fan Hai-Tao , Wang Hai , Chen Xiu-Hua
Published: September 2016

A genetic algorithm-based method is proposed to globally optimize the stacking sequence of multi-sandwich-panel composite structures for minimum weight with strength and buckling considerations. The prerequisites for the continuity between sandwich panels are first studied. To implement the summarized continuity rules in the evolutionary optimization, three newly constructed chromosomes are developed to encode the global stacking sequence with no additional repair. Genetic operators, including specialized mutation, swapping and crossover operators, are also developed to effectively explore the design space and keep the continuity rules followed. The Hashin criterion and maximum stress criterion are used to evaluate the strength of sandwich panels. A typical multi-sandwich-panel composite structure with identical and different core thicknesses is optimized to verify the validity and efficiency of the proposed method. It is found that much lighter solutions are obtained with an acceptable efficiency in all cases. It is also found that the weight of the multi-sandwich-panel composite structures can be further reduced when the core thicknesses are not identical.
Structure and microwave absorbing properties of carbon-filled ultra-high molecular weight polyethylene
Authors: Gulbin Victor N. , Tcherdyntsev Victor V.
Published: September 2016

Colloid composition based on the nanosized carbon powder, dispersed in complex mineral solvent, was elaborated. It was found that the composition can be used both as surface coating and as filler for an ultra-high molecular weight polyethylene matrix. A study of electromagnetic wave absorption showed that the coatings and composites thus obtained possess high microwave protection properties. Wave absorption of a coating 50 μm thick varies from −5 to −25 dB depending on frequency. A study of polymer composites filled with colloid composition, showed that increase in the filler content leads to the transition from chaotically dispersed to the oriented distribution of colloid composition particles in the polymer matrix. Tensile test showed that the polymer filled with colloid composition retains the mechanical properties close to those of pure ultra-high molecular weight polyethylene (UHMWPE). Microwave absorption gradually increases with increasing filler content in UHMWPE-based composites.
Synthesis of morphan derivatives with additional substituents in 8-position
Authors: Stefaowitz Janine , Schepmann Dirk , Daniliuc Constantin , Saito Susumu , Wünsch Bernhard
Published: September 2016

The morphan system (2-azabicyclo[3.3.1]nonane) as a substructure of morphine is of major interest in medicinal chemistry. Herein, the synthesis of morphan derivatives with additional substituents at the propano bridge is reported. In order to avoid the isolation of the smelly and volatile nitrile 6 and the very polar primary amine 9, an efficient one-pot, three-step sequential transformation of the mesylate 5 into amides 10 was developed. The key step of the synthesis was the stereoselective intramolecular opening of the epoxides 11a–d leading to the exo-configured 8-hydroxymorphans 12a–d. The configuration of the exo-configured hydroxymorphan 12d bearing the κ- and σ-pharmacophoric 3,4-dichlorophenylacetyl moiety was inverted by oxidation and stereoselective reduction. An X-ray crystal structure analysis of the benzamide 12c confirmed the relative configuration of the hydroxymorphans 12a–d and 14d.
Selective Activation of Resting-State Networks following Focal Stimulation in a Connectome-Based Network Model of the Human Brain
Authors: Spiegler Andreas , Hansen Enrique C. A. , Bernard Christophe , McIntosh Anthony R. , Jirsa Viktor K.
Published: September 2016

When the brain is stimulated, for example, by sensory inputs or goal-oriented tasks, the brain initially responds with activities in specific areas. The subsequent pattern formation of functional networks is constrained by the structural connectivity (SC) of the brain. The extent to which information is processed over short- or long-range SC is unclear. Whole-brain models based on long-range axonal connections, for example, can partly describe measured functional connectivity dynamics at rest. Here, we study the effect of SC on the network response to stimulation. We use a human whole-brain network model comprising long- and short-range connections. We systematically activate each cortical or thalamic area, and investigate the network response as a function of its short- and long-range SC. We show that when the brain is operating at the edge of criticality, stimulation causes a cascade of network recruitments, collapsing onto a smaller space that is partly constrained by SC. We found both short- and long-range SC essential to reproduce experimental results. In particular, the stimulation of specific areas results in the activation of one or more resting-state networks. We suggest that the stimulus-induced brain activity, which may indicate information and cognitive processing, follows specific routes imposed by structural networks explaining the emergence of functional networks. We provide a lookup table linking stimulation targets and functional network activations, which potentially can be useful in diagnostics and treatments with brain stimulation.
Numerical Modeling of Turbulent Flow Inside the Centrifugal Blower
Authors: Majid Almas
Published: September 2016

In this paper, turbulent flow inside the centrifugal blower has been studied numerically. The computational simulation is conducted by employing the Reynolds Averaged Navier­Stokes (RANS) approach. The standard k-ɛ model with enhanced wall treatment has been implemented for modeling the turbulent flow. Effects of different angular velocities have been studied on static pressure and mass flow rate. The numerical results shows that static pressure and mass flow rate significantly increase as the angular velocity of blades increases.
Federally Qualified Health Center Access and Emergency Department Use Among Children
Authors: Nath Julia B. , Costigan Shaughnessy , Lin Feng , Vittinghoff Eric , Hsia Renee Y.
Published: September 2016

OBJECTIVE:

To determine whether increasing access to federally qualified health centers (FQHCs) in California was associated with decreased rates of emergency department (ED) use by children without insurance or insured by Medicaid.

METHODS:

We combined several data sets to longitudinally analyze 58 California counties between 2005 and 2013. We defined access to FQHCs by county using 2 measures: FQHC sites per 100 square miles between 2005 and 2012 and percentage of Medicaid-insured and uninsured children served by FQHCs from 2008 to 2013. Our outcome was rates of ED use by uninsured or Medicaid-insured children ages 0 to 18 years. To determine the effect of changes in FQHC access on the outcome within a county over time, we used negative binomial models with county fixed effects and controls for preselected time-varying county characteristics and secular trends.

RESULTS:

Increased geographic density of FQHC sites was associated with ≤18% lower rates of ED visits among Medicaid-insured children and ≤40% lower ED utilization among uninsured children (P = .05 and P < .01, respectively). However, the percentage of Medicaid-insured and uninsured children seen at FQHCs was not associated with any significant change in ED visit rates among Medicaid-insured or uninsured children.

CONCLUSIONS:

Whereas increased geographic FQHC access was associated with lower rates of ED use by uninsured children, all other measures of FQHC access were not associated with statistically significant changes in pediatric ED use. These results provide community-level evidence that expanding FQHCs may have a limited impact on pediatric ED use, suggesting the need to explore additional factors driving ED utilization.
Impacts of urbanisation level and distance from potential natural mosquito breeding habitats on the abundance of canine dirofilariosis
Authors: Trájer Attila , Rengei Antal , Farkas-Iványi Kinga , Bede-Fazekas Ákos
Published: September 2016

Dirofilariosis is an emerging mosquito-borne veterinary and medical problem in the Northern hemisphere. The ecological investigation of 56 canine dirofilariosis cases in new endemic locations was performed in Szeged, Hungary. The aim was to analyse the influence of the spatial patterns of dog abundance and the potential mosquito breeding habitats on the spatial occurrence patterns of dirofilariosis in the city of Szeged. The limnoecological characterisation was based on the fluvial habitat classification of Amoros of natural water bodies; the built environment was evaluated using the UrbanisationScore urbanisation intensity measuring software. Dirofilaria immitis accounted for 51% and D. repens for 34.3% of the dirofilariosis cases, and in 20% of the cases only the Knott’s test was positive. It was concluded that most of the cases were related to locations with a medium to high urbanisation index, although the proximity of mosquito-bearing waters also played an important role in the observed spatial infection patterns. We found that the distance from potential mosquito habitats and the urbanisation intensity determine the abundance of dirofilariosis in urban environments.
Demonstration of homologous recombination events in the evolution of bovine viral diarrhoea virus by in silico investigations
Authors: Kővágó Csaba , Hornyák Ákos , Kékesi Violetta , Rusvai Miklós
Published: September 2016

Complete genome sequences of bovine viral diarrhoea virus types 1 and 2 (BVDV-1 and 2) deposited in the GenBank were submitted to bioinformatic analysis using a recombination-detecting software. The results indicate that recombination events are not rare in the case of BVDV, which frequently causes immunotolerance and, consequently, persistent infection in calves. The lack of specific immunity provides an ideal possibility for multiple infections by antigenically related but genetically different BVDV strains, and hence recombinations may occur. Among the 62 BVDV-1 genomes five recombinants and their possible parent strains, while among the 50 BVDV-2 genomes one simple recombinant and its parent strains were identified, which were supported by extremely strong probability values (P values varying between 1.26 × 10–4 and 1.58 × 10–310). Besides the newly identified recombinants, recombination events described previously were confirmed, but in some of these cases former information was completed with new data, or different parent(s) were suggested by the programme (RDP 4.46 BETA) used in this study.
A remény pszichológiája. Elméleti áttekintés az empíria tükrében
Authors: Kis Médea
Published: September 2016

E tanulmány célja magyar nyelven összefoglalást adni a remény mint lélektani konstruktum elméleti hátteréről, vizsgálati módszereiről, különféle megközelítések, hangsúlyos kutatási irányok egybevetésével, továbbá integratív igényű definíciót kínálni a nemzetközi és hazai eredmények figyelembe vételével. Az eredmények gyakorlati hasznosíthatósága is kifejtésre kerül. A remény mint személyiségjellemző a jövendőre, és az egyén számára értékes, de nem túl távoli cél elérésére irányuló várakozás, amelyet általában a nem kielégítő jelen állapot indukál. A reményteliség szintje érzelmi, kognitív, motivációs, viselkedéses és környezeti összetevői révén növelhető. Szerepe a kapcsolati kommunikáció gazdagságában, a munka-, szellemi, és sportteljesítményben, és nem utolsó sorban a betegségekből felgyógyulás és a poszttraumás növekedés folyamatában érhető tetten.
Amphibia, Anura, Bufonidae, Rhaebo ecuadorensis Mueses-Cisneros, Cisneros-Heredia & McDiarmid, 2012, and Anura, Hylidae, Phyllomedusa tarsius (Cope, 1868): range extensions and first records for Zamora-Chinchipe province, Ecuador
Authors: Székely Paul , Armijos-Ojeda Diego , Ordóñez-Delgado Leonardo , Székely Diana , Cogălniceanu Dan
Published: September 2016

We report the first provincial records for Rhaebo ecuadorensis Mueses-Cisneros, Cisneros-Heredia & McDiarmid, 2012,and Phyllomedusa tarsius (Cope, 1868) in Zamora-Chinchipe, southern Ecuador. The new locations are significant because they represent the southernmost records in Ecuador as well as the westernmost limits of the ranges of these two species.
A APLICABILIDADE DO MODELO DE GOVERNANÇA DE TECNOLOGIA DA INFORMAÇÃO: O CASO UNP
Authors: Granjeiro Breno Ricardo Rêgo , Costa Lúcia De Fátima Lúcio Gomes da
Published: September 2016

Nos últimos anos, com as mudanças ocorridas nas estruturas organizacionais, pode-se perceber que a área de Tecnologia da Informação passou a ser um dos componentes importantes nas empresas, e o uso da Governança de Tecnologia da Informação tem ganhado destaque, pois ela possibilita maior competitividade e alinhamento das iniciativas de TI com a estratégia do negócio. A Governança de Tecnologia da Informação se trata de um conjunto de processos para avaliar e direcionar o uso da TI para dar suporte à organização e monitorar seu uso para realizar planos. Este trabalho apresenta um estudo de caso de caráter descritivo e exploratório que teve o objetivo de analisar como o modelo de governança de TI se aplica a instituição Universidade Potiguar (UnP), localizada no município de Natal, no Rio Grande do Norte, bem como entender e explicar os aspectos que o norteiam, desde a origem da governança corporativa, como também a visão geral do modelo, definindo as suas caraterísticas e também compreender o uso de tal mecanismo com relação em gerar vantagem competitiva para a instituição. Para isso, foram analisados esses aspectos através de uma entrevista semiestruturada, respondendo a pergunta problema. Pode-se concluir que a área de TI serve de apoio à estrutura educacional da instituição, pois ela está diretamente ligada com metas e estratégia da Instituição, e se subdivide em cinco setores principais: Operações de TI; Security Office, Escritório de Projetos, Desenvolvimento de Sistemas e de Controles Internos de TI. A implantação do modelo na instituição ocorreu alinhada com o uso dos modelos de melhores práticas para aplicação da governança sendo eles: Control Objectives for Information and related Technology (COBIT); Information Technology Infrastructure Library (ITIL); Project Management Body of Knowledge (PMBOK), ISO2700 e Scrum, e o uso desse modelo garante integridade, disponibilidade, confiabilidade e confidencialidade dos serviços, informações e sistemas. Outro fato que se pode concluir que em relação ao uso do modelo de governança para obter vantagem competitiva, observou-se que é preciso garantir que a GTI exista efetivamente na organização e que esteja nos requisitos de compliance, o que garante uma melhor colocação no mercado, além de garantir que os recursos estão sendo utilizados da maneira correta.
Nilai-nilai Toleransi dalam Islam pada Buku Tematik Kurikulum 2013
Authors: Rusydiyah Evi Fatimatur , Hidayati Eka Wahyuni
Published: September 2016

This article discusses the values of tolerance found in the thematic text-book of 2013 curriculum. The thematic text-book has an important role in building students’ character, especially regarding the values of tolerance. This article aims to answer questions concerning the design of tolerant attitude in the thematic text-book for class one of elementary school, the advantage and deficiency of the book, and solutions for thematic text-book regarding tolerant attitudes. As a study of documentation, this article deals with eight themes on thematic text-book for class one of elementary school. In analyzing the data, this study refers to seven indicators of tolerant attitude using content analysis method. This study concludes that the design of tolerant attitudes consists of respect, collaboration, help, friend-ship, equality, harmony, freedom of worship. The advantage of the text-book is its identification of seven indicators, while its deficiency is related to the presence of pictures contradictory to the values of tolerance. The solution for its deficiency is to revise the explanation of words in the negative pictures very to contradict the values of tolerance.
Harmoni Lintas Agama Masyarakat Tengger
Authors: Hisyam Mohamad Ali , Kamarudin Wan Ali Wan Zailan
Published: September 2016

This paper attempts to closely portray interreligious harmony, especially between Muslim and Hindu community in Tengger, East Java. Tengger community are ingrained with their own culture and practicing their unique tradition. Through symbolic-interactionist approach, this paper supposes that this reality represents a cultural process which is simultaneously and flexibly flowing and growing. In the name of brotherhood and humanity, Tengger people are running their daily activities, discounting subjective differences among them. Sociologically, they are focusing on facing the reality as objective necessities where the self and the other are mutually understanding and complementing each other. In this regard, they have improved the way of interaction, from saya-and-mereka perspective to kami-andkita approach. Social activities and religious/cultural rites symbolically become communicative device of inter-relation among the people. Muslim and Hindu harmony in this community denotes multicultural interaction that entails social involvement of members of community. Tengger people, as an animal symbolicum, strive to construct, expand and (re)interpret the symbols for building harmony.
Measuring the Informativeness of Market Statistics
Authors: Kim Kyungmin
Published: September 2016

Market statistics can be viewed as noisy signals for true variables of interest. These signals are used by individual recipients of the statistics to imperfectly infer different variables of interest. This paper presents a framework under which the 'informativeness' of statistics is defined as their efficacy as the basis of such inference, and is quantified as expected distortion, a concept from information theory. The framework can be used to compare the informativeness of a set of statistics with that of another set or its theoretical limits. Also, the proposed informativeness measure can be computed as solutions to familiar problems under a range of assumptions. As an application, the measure is used to explain the difference in usage levels of temperature derivatives across different base weather stations. The informativeness measure is found to be at least as effective as city size measures in explaining the difference in usage levels.
Non-Linear Phillips Curves with Inflation Regime-Switching
Authors: Nalewaik Jeremy
Published: September 2016

Building on the results in Nalewaik (FEDS 2015-93), this work models wage growth and core PCE price inflation as regime-switching processes, whose characteristics in the 1970s, 1980s and early 1990s differ fundamentally from their characteristics in the 1960s and from the mid-1990s to present. The key innovation here is the addition to the models of fundamental driving variables like labor-market slack, and the evidence strongly suggests a non-linear effect of slack on wage growth and core PCE price inflation that becomes much larger after labor markets tighten beyond a certain point. The results are informative for assessing the likelihood and risks of meeting certain inflation targets on a sustained basis.