bluuebunny/crossref_metadata_2025 huggingface dataset:
Intralesional Acyclovir for Cutaneous Warts
Authors: Hamid Ayyash Mazin , Saad Abdlkadir Sura
Published: November 2023

Cutaneous warts are a common skin problem in routine dermatological practice.
There are many clinical modalities, but there are failure and recurrence. The current study aimed to evaluate the efficacy and safety of intralesional acyclovir in
treating cutaneous warts. An analytic clinical trial study was conducted in
Iraq/Baghdad/Al-Yarmouk Teaching Hospital from November 2021 to May 2022.
The current study adopted A convenient sampling method to enroll 30 patients with
cutaneous warts. The patients had intralesional acyclovir (70 mg/ml) injected into
warts. The treatment was repeated at two-week intervals until complete clearance
or for a maximum of 5 sessions. According to the current study's results, 30 patients
were enrolled in the current study. The mean age was 23.7 (±12.7) years. Most of
the patients had an age of more than 14 years. Females constituted more than half
of the sample. Regarding the treatment outcome, 19 (63.3%) patients were cured,
and 10 (33.3%) failed to cure. In comparison, one patient had a recurrence after
being cured in three sessions. Regarding the patients who were cured, 8 (42.1%)
patients were cured in two sessions, 6 (31.6%) were cured in three sessions, 2
(10.5%) were cured in one session, and 2 (10.5%) patients were cured in four sessions. In contrast, 1 (5.3%) patient was cured in five sessions. Severe pain during
injection was the commonest side effect (66.6%), followed by bullous reaction
(30%0), bleeding at the site of injection (20.0), and pain for a few days (16.7%).
In conclusion, intralesional acyclovir was found to be effective and safe with few
and transient side effects.
Keyword: Cutaneous; Patients; Bleeding.
Association between Serum Vitamin B12 and Folate Levels with
Type 2 Diabetes Mellitus On Metformin Therapy
Authors: N. Tawfeeq Yasmeen , N. Hilal Nihad , Zaidan Zaidan J.
Published: November 2023

Background: Vitamin B12 is a water-soluble vitamin, and its lack causes the methylation process to be disrupted, further resulting in the formation of abnormal fatty
acids, which results in neurological manifestations. The water-soluble vitamin folate, often known as folic acid or vitamin B9, is especially vital during high cell
division and growth periods. Objective: The study aims to evaluate serum vitamin
B12 and folate levels in type 2 diabetic patients with and without metformin therapy and to correlate their levels with other parameters in type 2 diabetes mellitus
(T2DM) patients. Subjects and Methods: A cross-sectional controlled study that
included 90 participants, 60 type 2 diabetes mellitus patients with metformin therapy designated as (the metformin group) and 30 type 2 diabetes mellitus without
metformin therapy considered as (the control group). The study was conducted
from December 2021 to the end of March 2021 at private internal medicine clinics
in Tikrit City, Iraq. Blood samples were assessed for serum vitamin B12 and folate
using Cl-900i Chemiluminescence Immunoassay Analyzer and glycated hemoglobin HbA1c using AFIAS Analyzer in all metformin and control groups. Result:
The study showed that there were significant differences in vitamin B12 of (p <
0.01) and folate of (p < 0.05) between the metformin group and the control group.
Significant negative correlations were found between vitamin B12 and diabetes
mellitus (DM) duration and HbA1c. Folate was negatively correlated and highly
significant with DM duration and HbA1c (p < 0.01). Conclusion: The results
showed low vitamin B12 and folate levels in T2DM patients. Vitamin B12 and
folate were negatively correlated with DM duration and HbA1c. The results suggest a higher risk of vitamin B12 and folate deficiency with metformin use and
emphasize the concern of vitamin B12 and folate deficiency in T2DM patients.
Keywords: Type 2 Diabetes Mellitus (T2DM); Vitamin B12; Folate; DM
duration; HbA1c.
Molecular and morphological characterization of the seed gall nematodes
Anguina tritici from central and southern Iraq
Authors: H. Aldarraji Mohammed , Alwaily Dhia S. , Heydari Ramin
Published: November 2023

This is the first morphological investigation of the wheat gall nematodes Anguina
tritici found on wheat in southern and midland areas of Iraq. A survey was conducted, and samples were collected from wheat fields in eight governorates (Diyala, Baghdad, Qadisiyah, Najaf, Wasit, Maysan, Dhi Qar and Basra, 3 regions
each and three fields for each region during the 2020-2021 growing season.
Wheat-gall nematodes were extracted and observed under a stereomicroscope.
Nematodes of interest were hand-picked, identified and photo-micro-graphed using a microscope equipped with a digital camera. Two species of anguinid nematodes (Anguinidae: Tylenchida) were found and characterized. This species is
characterized by its 810-905 mm long body, body slightly curved to almost
straight, with a 9-10 μm small stylet with delicate lip region very slightly offset,
pharyngeal lobe long, wider than adjacent body part and 16-17µm broad, distance of dorsal gland orifice to the style 2-4, position of dorsal gland orifice to the
style base expressed as a percentage of the total style length20-40 µm. Anterior
end to the valve of the median bulb 67 -72µm; anterior end to excretory. Tail long,
gradually tapering to an acute tip without mucro 61 -70 µm. As for the molecular
identification and comparison with the GenBank, sequencing of Dhi Qar samples
showed having three transitions at sites 59,125,168 G\T, G\T, and G\A, respectively, and one transversion at 140 G\C site. It was found that the ITS gene has a
compatibility of 98% with the original sequence conserved in the Genbank with ID
KC818619. As for the Anguina tritici isolated from Basra, it contains two transitions at locations 247 and 253 C\T, four transversions 238,245,249, 251 G\T,
G\C, A\C, and T\A, respectively, with similarity of 97%. Maysan samples were
compatible with 98% and had one transition at 168 G\A site and three transversions at the locations 125,128.25 G\T. ITS gene from Diyala showed 98%
compatibility with the sequence in GenBank, having one transition at locus G\A 93
and three transversions at 83,78,59 G\T, G\C, and G\T, respectively. Two
transversions in locations 59,117 nucleotide G\T, A\C in Al-Kut samples, and at
125,142 G\T, G\C in Baghdad ones, while Najaf samples had one transversion, and
one transition in sites 213, 234 G\C, C\T respectively, as all of them showed 99%
similarity with the original sequence in GenBank.
Bionatura http://dx.doi.org/10.21931/RB/CSS/2023.08.97 2
Keywords: Field crop, PCR, PPN, wheat
Preparation of Chalcone-Azo reagents and study of their chemical analysis,
thermal studies, and biological effects against fungi
Authors: A.M. Alhar Maysaa
Published: November 2023

Chalcone reagents are used in various fields because of their biological, medical, and medicinal properties. Therefore, this study aimed to prepare a new reagent of Chalcone–Azo and study its chemical and physical properties using
different techniques. In this recent work, four reagents were created and tested
using thermal behavior in stability curves, solubility in various solvents, and
spectral characterization like UV-visible FT-IR. In addition, a biological study
was conducted to estimate the effect of these reagents on two types of fungi.
Results showed that spectral characterization methods (UV-visible and FT-IR)
showed that new groups of compounds were formed, and starter reactants disappeared. This is good proof of forming new reagents. The outcome of thermal
behavior in stability curves solubility in various solvents emphasizes these results. The study of using the new reagents as antifungal substances showed that
reagent {3} had the highest effect on inhibiting study fungi growth, followed by
reagent {4}.
Keywords: Reagent, analytical, thermal, fungi, bioassay
Experiences of Patients With Chronic Obstructive Pulmonary Disease Using the Apple Watch Series 6 Versus the Traditional Finger Pulse Oximeter for Home SpO2 Self-Monitoring: Qualitative Study Part 2 (Preprint)
Authors: Liu Yuxin , Arnaert Antonia , da Costa Daniel , Sumbly Pia , Debe Zoumanan , Charbonneau Sylvain
Published: November 2023

BACKGROUND

Amid the rise in mobile health, the Apple Watch now has the capability to measure peripheral blood oxygen saturation (SpO2). Although the company indicated that the Watch is not a medical device, evidence suggests that SpO2 measurements among patients with chronic obstructive pulmonary disease (COPD) are accurate in controlled settings. Yet, to our knowledge, the SpO2 function has not been validated for patients with COPD in naturalistic settings.

OBJECTIVE

This qualitative study explored the experiences of patients with COPD using the Apple Watch Series 6 versus a traditional finger pulse oximeter for home SpO2 self-monitoring.

METHODS

We conducted individual semistructured interviews with 8 female and 2 male participants with moderate to severe COPD, and transcripts were qualitatively analyzed. All received a watch to monitor their SpO2 for 5 months.

RESULTS

Due to respiratory distress, the watch was unable to collect reliable SpO2 measurements, as it requires the patient to remain in a stable position. However, despite the physical limitations and lack of reliable SpO2 values, participants expressed a preference toward the watch. Moreover, participants’ health needs and their unique accessibility experiences influenced which device was more appropriate for self-monitoring purposes. Overall, all shared the perceived importance of prioritizing their physical COPD symptoms over device selection to manage their disease.

CONCLUSIONS

Differing results between participant preferences and smartwatch limitations warrant further investigation into the reliability and accuracy of the SpO2 function of the watch and the balance among self-management, medical judgment, and dependence on self-monitoring technology.
Understanding Loneliness in Younger People: Review of the Opportunities and Challenges for Loneliness Interventions (Preprint)
Authors: Shah Hurmat Ali , Househ Mowafa
Published: November 2023

UNSTRUCTURED

Loneliness affects the quality of life of people all around the world. Loneliness is also shown to be directly associated with mental health issues and is often the cause of mental health problems. It is also shown to increase the risk of heart diseases and other physical illnesses. Loneliness is studied both from the social and medical sciences perspectives. There are also interventions on the basis of health informatics, information and communication technologies (ICTs), social media, and other technological solutions. In the literature, loneliness is studied from various angles and perspectives ranging from biological to socioeconomical and through anthropological understandings of technology. From the ICT and technological sides, there are multiple reviews studying the effectiveness of intervention strategies and solutions. However, there is a lack of a comprehensive review on loneliness that engulfs the psychological, social, and technological studies of loneliness. From the perspective of loneliness informatics (ie, the application of health informatics practices and tools), it is important to understand the psychological and biological basis of loneliness. When it comes to technological interventions to fight off loneliness, the majority of interventions focus on older people. While loneliness is highest among older people, theoretical and demographical studies of loneliness give a U-shaped distribution age-wise to loneliness; that is, younger people and older people are the demographics most affected by loneliness. But the strategies and interventions designed for older people cannot be directly applied to younger people. We present the dynamics of loneliness in younger people and also provide an overview of the technological interventions for loneliness in younger people. This paper presents an approach wherein the studies carried out from the perspectives of digital health and informatics are discussed in detail. A comprehensive overview of the understanding of loneliness and the study of the overall field of tools and strategies of loneliness informatics was carried out. The need to study loneliness in younger people is addressed and particular digital solutions and interventions developed for younger people are presented. This paper can be used to overcome the challenges of technological gaps in the studies and strategies developed for loneliness. The findings of this study show that the majority of interventions and reviews are focused on older people, with ICT-based and social media–based interventions showing promise for countering the effects of loneliness. There are new technologies, such as conversational agents and robots, which are tailored to the particular needs of younger people. This literature review suggests that the digital solutions developed to overcome loneliness can benefit people, and younger people in particular, more if they are made interactive in order to retain users.
Baixos níveis de vitamina A em mulheres acompanhadas durante o pré-natal
Authors: Orrico Géssica Santana , Ramos Michele de Santana Xavier , Guedes Ellen de Moraes , Fonseca Ana Lucia Barreto da , Rabelo Doris Firmino , Cruz Simone Seixas da
Published: November 2023

A deficiência de vitamina A (DVA) é definida quando as concentrações desse nutriente, nos tecidos, são baixas, podendo produzir consequências adversas à saúde, tais como: complicações durante a gravidez e maior risco de parto prematuro e baixo peso ao nascer. O objetivo deste artigo foi investigar a prevalência de hipovitaminose A e seus fatores associados em gestantes usuárias de serviços públicos de saúde em um município do interior da Bahia. Foi realizado um estudo transversal, desenvolvido com 76 gestantes acompanhadas em unidades de saúde da família que prestam assistência pré-natal. Os dados foram coletados por meio de entrevistas, aplicação de questionário e realização de exame laboratorial. As gestantes foram classificadas quanto à presença de DVA, quando a dosagem de retinol sérico foi menor que 0,20 mg/L. Foram estimadas as frequências das variáveis do estudo. A investigação dos fatores associados às deficiências de hipovitaminose A foi realizada por meio da estimativa da razão de prevalência (RP) e seu respectivo intervalo de confiança a 95%, com nível de significância de 5%. A prevalência de DVA materna foi de 13%, entretanto, não houve associação estatisticamente significante com as demais variáveis estudadas. Contudo, foi observada maior ocorrência de DVA nas mulheres com renda familiar menor que dois salários mínimos, que vivem em domicílios com quatro pessoas ou mais, que têm mais de dois filhos, que tiveram gravidez não planejada, início do pré-natal no segundo ou terceiro trimestre, hipertensão arterial, infecção urinária, ausência de vacinação antitetânica e hábito de fumar na gestação. Os dados indicam maior incidência de DVA quando há piores condições de vida/saúde entre as características estudadas. Todavia, ainda são necessários estudos mais robustos para a formulação de ações sociais que visem prevenir tal ocorrência e promover a saúde gestacional.
GLORIFICATION OF THE IVERON ICON OF THE MOTHER OF GOD IN ARCHITECTURE (BASED ON MATERIALS FROM THE OREL PROVINCE)
Authors:   Central Russian Institute of Management, Branch of RANEPA, BELINSKAYA N.I.
Published: November 2023

The purpose of the article is to consider the features of the glorification of the Iveron Icon of the Mother of God in the architecture of the period of the Grand Ducal Couple Sergei Alexandrovich Romanov and Elizaveta Feodorovna Romanova. The article describes the history of two architec-tural projects to glorify the Moscow shrine – the Iveron Icon of the Mother of God, embodied with the partici-pation of the Moscow Governor-General, Grand Duke Sergei Alexandrovich, Grand Duchess Elizabeth Feodorovna, as well as representatives from their entourage. The significant contribution of Grand Duke Sergei Alexandrovich to the development of the "Russian style" in architecture is mentioned, and individual architects and engineers – to its popularization in the Russian province. The decisive role of the Moscow Governor-General, Grand Duke Sergei Alexandrovich, in the creative fate of some architects and engineers is traced. The methodology of studying this topic includes a number of stages and approaches, which may vary depending on the specific task in the study. As a result, the author concludes that the spread of the "Russian style" in the regions of Russia was due to the state patronage and the highest support of this architectural direction.
THE HISTORICAL SIGNIFICANCE OF A.P. RUDANOVSKY’S DRAFT CONSTITUTION OF IN THE CONSTITUTIONAL LAWMAKING OF RUSSIA AT THE BEGINNING OF THE 20th CENTURY
Authors:   Orel State University named after I.S. Turgenev, ARONOV D.V. , MINAKOV S.T. ,   Orеl State University named after  I.S. Turgenev
Published: November 2023

The main purpose of the article is to consider the constitutional project under study, which is practically not mentioned in modern historical and historical-legal science. This project was developed by A.P. Rudanovsky at the beginning of the 20th century and published in 1905. The authors define the structure of the project and the mechanisms of public administration embedded in it. A comparative analysis of the document with other drafts of the basic law of the early 20th century, proposed by Russian liberal scientists and politicians, is carried out. The specifics of the mechanisms of public administration embed-ded in the project are revealed; it is proposed to classify the project as so-called "individual" or "private", which helps to understand the atmosphere of intellectual search in the field of constitutional law-making of the early 20th century. As a result, the authors conclude that a broader consideration of such sources reveal a certain category of private and individual projects, whose appearance is associated with the atmosphere of expectation of change in which the Russian intellectual and political elite lived at the beginning of the 20th century.
FEATURES OF THE FORMATION AND THE DEVELOPMENT OF CITIZENSHIP IN THE LEGISLATION OF RUSSIA
Authors:   Orel Law Institute of the Ministry of Internal Affairs of the Russian Federation named after V.V. Lukyanov, BELYAEVA O.V. , GOMOZOVA O.Ju. ,   Orel Law Institute of the Ministry of Internal Affairs of the Russian Federation named after V.V. Lukyanov
Published: November 2023

The purpose of the article is to study the historical features of the of the citizenship formation during the existence of the Russian Empire and the institution of citizenship from the Soviet period to the present. The authors put forward theses on the relationship between the statuses of a subject and a citizen, according to the analysis of the regulatory database of the given periods. Special attention is paid to the basic requirements for the acquisition and termination of the status of a subject and citizen at the stages of its development; there is a clear democratization of Russian society. Based on the conducted research, the main trends of the state approach to obtaining the status of a citizen are formulated. Specific legislative acts that regulate the issue under the study is considered. The reasoned scientific point of view is given. As a result, the authors note that the Institute of Russian citizenship is a relatively young institution, and therefore the process of further democratic development and transformation is relevant.
IDEOLOGICAL AND POLITICAL FOUNDATIONS IN THE DEVELOPMENT OF THE DON KOMSOMOL IN THE 20s -30s OF THE 20th CENTURY
Authors:   State Duma of the Federal Assembly of the Russian Federation, DROBOT M.V.
Published: November 2023

The purpose of the article is to analyze ideological and political foundations in the development of the Don Komsomol in the 20s -30s of the 20th century. The author emphasizes that the problem of the Komsomol participation in the restructuring of the spiritual sphere of life in the 1920s is relevant due to the urgent need to understand the processes of formation of a new social order and a new culture that arose during this period. The author notes that the establishment of a new social system with developed political and ideological control cannot be evaluated unambiguously and only positively, but the constructive experience itself, the process of finding solutions require understanding. On the basis of archival sources, the author draws conclusions about the work, powers, as well as changes in the activities of the Komsomol. The author characterizes the changes that took place in the organization during the period under study and emphasizes that the ongoing transformations depend on the socio-political transformations carried out in the Soviet state, such as literacy, mass de-fense activities, sports, cultural and educational activities, agricultural extension, work with the pioneer organization, etc. Special attention is paid to the economic campaign of the Komsomol, including the creation of Komsomol shock brigades at enterprises.
THE HISTORY OF THE DEVELOPMENT OF THE CHILDREN RECREATION AND WELLNESS SYSTEM IN COOPERATION WITH THE KOMSOMOL AND THE PIONEER ORGANIZATION IN THE 40-50S OF THE 20-th CENTURY
Authors:   Central Russian Institute of Management, Branch of RANEPA, TSYGANKOVA E.A.
Published: November 2023

The purpose of this article is to study the develop-ment of the children recreation and wellness system in cooperation with the Komsomol and the Pioneer organization in the 40-50s of the 20-th century. The organization peculiarities of the pioneer camps during the Great Patriotic War and the postwar years, including their educational and labor character, are emphasized. The Komsomol normative documents are analyzed; the content of political and educational work, as well as labor training, is considered as the most important component of political education. The features of the new types of pioneer camps that appeared in the 50s such as tourist, intercalative and school are studied. The article analyzes the "Regulations on the rural pioneer camp" (1951), which defined the tasks, structure; requirements for the territory and rooms; the pioneer camp management; financing; accounting, reporting; work planning; approximate daily routine.
THE SECOND EMPIRE AND NAPOLEON III IN THE ASSESSMENT OF BRITISH CONTEMPORARIES IN THE MIDDLE OF THE 19TH CENTURY
Authors:   Orel State University named after I.S. Turgenev, GELLA T.N.
Published: November 2023

The purpose of the article is to consider the features of the formation of the Second Empire and consolidation of power of Napoleon III through the assessment of British contemporaries in the middle of the 19th century. Depending on the objectives of the study, different methodologies can be used to study the Second Empire and Napoleon III. On the basis of the historical documents study, archives, letters and other sources, the author considers how Napoleon III and the Second Empire influenced France and the world histo-ry. Some ecological problems of perception of images of the Second Empire in British society in the first ten years of the reign of Emperor Napoleon III are revealed. On the basis of English periodicals and domestic and English-language literature studies, the author makes an attempt to construct images of the Bonapartist regime and the personality of Napoleon himself as a politician in the perception of a medieval Englishman. The main emphasis is on the analysis of the internal policy of Napoleon III.
Size selected NET‐Seq reveals a conserved architecture of transcription units around yeast genes.
Authors: Mellor Jane , Xi Shidong , Murray Struan , Lorenz Philipp
Published: November 2023

Genomes from yeast to human are subject to pervasive transcription. A
single round of pervasive transcription is sufficient to alter local
chromatin conformation, nucleosome dynamics and gene expression, but
experimentally is can be hard to distinguish from background signals.
Size selected native elongating transcript sequencing (ssNET-Seq) was
developed to precisely map transcription units (TU) independent of
expression levels. RNAPII-associated nascent transcripts are
fractionation into different size ranges before library construction.
When anchored to the transcription start sites (TSS) of annotated genes,
the combined pattern of the output metagenes define the expected
reference pattern for a TU. Bioinformatic pattern matching to the
reference identified 9542 TU in Saccharomyces cerevisiae, of
which 47% are coding and 53% are non-coding. 3113 (33%) are newly
identified unannotated non-coding TU. Anchoring all TU to the TSS or
polyadenylation site (PAS) of annotated coding regions reveals
distinctive architectures of linked pairs of divergent TU approximately
200nt apart. The Reb1 transcription factor is enriched 30nt downstream
of the PAS only when an upstream (TSS-60nt) non-coding TU co-occurs with
a downstream (TSS+150nt) coding TU and supports nucleosome depletion in
the generation of the pervasive nascent transcriptome. The potential for
extensive transcriptional interference is evident from low abundance
unannotated TUs with variable TSS (median-240nt) initiating within a
500nt window upstream of, and transcribing over, the promoters of
protein coding genes. This study confirms a highly interleaved yeast
genome with different types of transcription units altering the
chromatin landscape in distinctive ways, with the potential to exert
extensive regulatory control.
Residential greenness during pregnancy and early life and development of asthma up to 27 years of age: The Espoo Cohort Study
Authors: Rantala Aino K. , Paciência Inês , Antikainen Harri , Hjort Jan , Hugg Timo , Jaakkola Maritta , Jaakkola Jouni
Published: November 2023

Background: Evidence on the effects of residential green spaces
on asthma is contradictory. We investigated potential association
between the amount of greenness in the residential area during pregnancy
and early life and development of asthma in the first 27 years of life.
Methods: The study population included all 2568 members of the
Espoo Cohort Study, Finland. We calculated individual-level exposure to
green space measured as cumulative Normalized Difference Vegetation
Index (cumNDVI in unit-months) within 300 m of the participant’s
residence during pregnancy and the first two years of life in both
spring and summer seasons. The onset of asthma was assessed using
information from the baseline and follow-up surveys. Results:
Exposure to residential greenness in the spring season during pregnancy
was associated with an increased risk of asthma up to 6 years of age,
with an adjusted hazard ratio (aHR) of 3.72 (95% confidence interval
(CI) 1.11-12.47) per a unit increase in cumNDVI. Increased greenness in
the summer during pregnancy associated with asthma with an aHR of 1.41
(95% CI 0.85-2.32) up to 6 years. The effect was found to be related to
increased greenness particularly during the third trimester of
pregnancy, with an aHR of 2.37 (95% CI 1.36-4.14) per unit increase of
cumNDVI. These associations were weaker at the ages of 12 and 27 years.
No association was found between NDVI in the first two years of life and
the development of asthma. Discussion: Our findings provide
evidence that exposure to greenness during pregnancy increases the risk
of developing asthma.
Wind speed surplus in wind farm wakes quantified from satellite SAR and mesoscale modeling
Authors: Hasager Charlotte Bay , Imber James , Fischereit Jana , Fujita Aito , Dimitriadou Krystallia , Badger Merete
Published: November 2023

Satellite SAR provides ocean surface wind fields at 10 m above sea
level. The objective is to investigate the capability of Synthetic
Aperture Radar (SAR) satellite StriX observations for mapping offshore
wind farm wakes. The focus is on the conditions under which an apparent
wind speed surplus is generated, measured in 48% of the 67 images
available. The results compare well to Sentinel-1 observations, showing
a 34% surplus rate during several years based on 1171 images. Three
wind speed surplus cases have been studied in detail using the mesoscale
Weather, Research, and Forecasting model (WRF) model with two wind farm
parametrizations. The SAR-based observations and WRF model compare for
most cases, though only when Turbulent Kinetic Energy (TKE) is included
in the wind farm parametrization. The TKE mixes higher momentum
downwards in a stable atmosphere, causing surface wind speed surplus
near the surface.
Characteristics of Kindergarten’s Village Education Community Curriculum Operation: Focusing on the case of public kindergartens in ‘A’ City
Authors:   The Korean Society for the Study of Local Education Management, Lee Hae Song , Kim Hoon Ho
Published: November 2023

The purpose of this study is to examine the perception of kindergarten teachers on village education community education and how the village education community curriculum is operated in kindergartens by subdividing it into innovative kindergartens and general kindergartens. To achieve this goal, focusing on the case of ‘A’ city, the current study investigated perceptions of public kindergarten teachers of village education community education, curriculum operation status, difficulties, and improvement requirements. The followings are the summary of the main findings from this study. First, kindergarten teachers in general positively recognized the concept of the village education community, and teachers working in innovative kindergartens were not only more aware of the concept of the village education community than general kindergarten teachers, but also recognized a higher degree of usefulness of village education community on early childhood education. Second, kindergarten teachers perceived greater difficulty in operating the curriculum that are operated through consultation with the community(village), rather than operating curriculum based on the topic of the community and curriculum that utilize the community resources. Third, kindergarten teachers pointed out the lack of 'promotion’ and ‘resources and infrastructure as the major hindrance factors, and there was a high demand for improvement on the ‘increase in the participation of the local community and ‘diversification of the programs’ operated by village education community curriculum.
Understanding the Experience of Administrative Staffs from the School Context Perspective
Authors:   The Korean Society for the Study of Local Education Management, Sohn Youngsoon , Woo Myungsuk
Published: November 2023

This study is a qualitative case study that comprehensively understands the experiences of administrative staffs at A high school through four dimensions: situated, professional, material, and external context. While complaints in situational context such as school location and external context such as work support from higher institutions tended to be offset in relation to professional collusion, professional context related to school management such as consultative communication culture is a factor that allows members to work with psychological stability in warm relationships. The material context such as budget, facilities, and human resources is a factor directly related to the work of administrative employees and has the greatest impact on their experiences. Based on the understanding of the experiences of administrative staffs, the followings are suggested to enhance administrative staffs’ experience. First, administrative staffs should be able to actively participate in various communication structures in the school. Second, for tasks in which they commonly complain of difficulties, the transfer to higher institutions or professional supports should be provided. Third, in order to develop expertise to handle various school field cases, the formation of out-of-school networks that can be consulted on business should be institutionalized.
Examining the relationship between high school student's post-graduation career plans, college major choices and academic achievement
Authors:   The Korean Society for the Study of Local Education Management, Kim Yongho , Kim Youngsik
Published: November 2023

In this study, we investigated the relationship between high school students’ post-graduation career plans, college major choices and academic achievement. Drawing upon data from the first and second years of the Korean Education and Employment Panel II, we explored the relationship between students' post-graduation career plans, their choice of college major during the second year of high school, and their academic achievement in the third grade utilizing multiple regression approaches.
The findings revealed a positive correlation between college aspiration during the second year of high school and higher academic achievement in the third year of high school. Students who set specific goals for college admission demonstrated a better academic performance compared to those who did not. Conversely, no statistically significant relationship is observed between college major choices during the second year of high school and their academic achievement in the third 3rd year of high school.
Based on these results, it is confirmed that the aspiration to pursue college among high school students is positively related to academic achievement, serving as a motivating factor for individuals. Therefore, the findings of this study underscores the significance of goal-setting during the high school years, thereby the importance of career education and counseling. The findings of this research also have policy implications, highlighting the need to prioritize goal-setting among high school students and provide adequate support for students’ career development.
Risk Factors for and Risk of Peripheral Artery Disease in Swedish Persons with Type 2 Diabetes Mellitus: a Nationwide, Register-Based Study
Authors: Avdic Tarik , K. Carlsen Hanne , Isaksson Rikard , Gudbjörnsdottir Soffia , Mandalenakis Zacharias , Franzén Stefan , Sattar Naveed , Beckman Joshua A , McGuire Darren K , Eliasson Björn
Published: November 2023

Objective: To investigate to what extent having control of peripheral artery disease (PAD) risk factors associates with the risk of incident PAD in persons with type 2 diabetes. Research Design and Methods: 148 096 persons with type 2 diabetes in the Swedish National Diabetes Register between 2005 and 2009 were included, and matched with 320 066 controls on the basis of age, sex and county. Few controls who developed type 2 diabetes after recruitment, during wash-in (<0.2%), were not censored, but were instead matched with two new controls. Persons with type 2 diabetes were evaluated according to the number of PAD risk factors beyond recommended guide-line levels at baseline, including low-density lipoprotein cholesterol, blood pressure, smoking, glycated hemoglobin, and estimated glomerular filtration rate. Incident PAD events were ascertained from 2006 to 2019. Results: A graded association was observed between the number of PAD risk factors not at target and incident PAD in persons with type 2 diabetes. The adjusted hazard ratio for PAD was 1.41 (95% confidence interval [CI], 1.23–1.63) for type 2 diabetes with all PAD risk factors within target compared with controls matched for sex, age and county but not risk factor status, contrasted with 9.28 (95% CI, 3.62-23.79) for all 5 PAD risk factors not at target. CONCLUSIONS: A graded association was observed between increasing number of PAD risk factors not at target and incident PAD in patients with type 2 diabetes.
Monitoring the degree of dilution during directed energy deposition of aluminum bronze and H13 tool steel using optical emission spectroscopy
Authors: Schmidt Malte , Partes Knut , Rajput Rohan , Phochkhua Giorgi , Köhler Henry
Published: November 2023

Controlling heat transfer in casting tools is a key quality aspect. It can be improved by selectively applying volumetric aluminum bronze (CuAl9.5Fe1.2) sections in the core of the tools and subsequently depositing these cores with hard-facing H13 tool steel. Directed energy deposition (DED) can be used for both additive manufacturing of aluminum bronze and hard-facing by depositing the filler material onto a substrate surface or previously manufactured bodies. A sufficient metallurgical bonding of the deposited filler material and the underlying layer must be ensured. Hence, the dilution is a key factor for quality assurance. However, high dilution of the underlying layer and the filler material negatively affects the desired properties and must be monitored. Optical emission spectroscopy of the DED process emissions is investigated by comparing the emission lines of the individual elements comprising the base and the filler materials. Multiple single tracks using aluminum bronze as the filler material are laser-cladded with varying power, onto the two different types of substrates, i.e., mild steel S355 (1.0570) and hot working tool steel H11 (1.2343). Additionally, single tracks of H13 (1.2344) are deposited with varying laser powers onto an additively manufactured core of aluminum bronze. Both resulting in deposition tracks with varying dilution values. Multiple emission lines of Cr, Fe, Cu, Al, and Mn are detected and measured (line intensity). Line intensity ratios using the element emission lines are calculated and correlated with the respective metallographic results of the deposition tracks (dilution and chemical composition). Deposition tracks with a higher dilution (CuAl9.5Fe1.2 onto S355/H11 as well as H13 onto CuAl9.5Fe1.2) showed an increased line intensity ratio of the underlying material to the filler material. Moreover, this technology was transferred in a multilayer industrial application.
Co-occurrence of leukemia, Crohn’s disease, and tuberous sclerosis in one patient
Authors: Ahn Yoon Ji , Park Dasom , Kim Mi Jin , Choe Yon Ho , Kwon Youngse , Kwon Yiyoung
Published: November 2023

Leukemia and Crohn’s disease are both diseases that can be influenced by genetic factors. Tuberous sclerosis complex (TSC) is a rare autosomal dominant neurogenetic disorder caused by genetic mutation. This report presents a pediatric case of concomitant development of leukemia, Crohn’s disease, and TSC. We aimed to study the pathogenesis of each disease and report this case to provide data for future reports and research on correlation of these three diseases.
Exploring Healthcare Practitioners’ Knowledge of Rare Diseases in Cameroon
Authors: Ngoumou Rose-Danielle , Bidzogo Ekobono Louis Marie Gael , Ngoumou Titus Yannick
Published: November 2023

Rare diseases (RD) are complex medical incidents that constitute a burden for health systems globally. In Cameroon, the absence of a national framework for RDs means that very little is known about these diseases. Many health professionals due to the rarity of cases and complexity of symptoms, face challenges in detecting and treating them. The aim of this paper is to examine the knowledge of Cameroonian physicians on RDs in order to highlight the medical constructions of RDs in Cameroon. The study is cross-sectional and associates quantitative and qualitative research approaches with 23 health practitioners who responded to an open-ended questionnaire to (1) evaluate their knowledge of RDs, (2) describe the medical discourse on RDs in Cameroon and (3) identify prevailing RDs in Cameroon. The study showed on the one hand that, health professionals have strong theoretical knowledge of RDs. About 40.9% know that an RD is one that has a very low prevalence. 73.1% have come across a case of RD in their practice. RDs practitioners indicated they have encountered in their practice were mainly Down syndrome, hemophilia, and G6PD. 81% say they have difficulties detecting an RD. On the other hand, there are certain health practitioners who view that RDs are not (yet) a public health concern in Cameroon when there is a rise of non-communicable diseases like high blood pressure, diabetes, etc. Treatment strategies highlighted were mainly multidisciplinary consults, surgery, and specialized care. The study suggests that decision makers and practitioners should design strategies to strengthen expertise for the diagnostic and management of RDs in Cameroon. Also, health practitioners should be trained regularly on how to manage RDs.
Obtaining the physical and mechanical characteristics of limnoglacial deposits in St. Petersburg for constructing a soil mathematical model
Authors:   L. N. Gumilyov Eurasian National University, Zhussupbekov A. Zh. , Ulitsky V. M. ,   St. Petersburg State University of Railways of Emperor Alexander I, Dyakonov I. P. ,   Saint Petersburg State University of Architecture and Civil Engineering, Nikolaeva M. V. ,   Saint Petersburg State University of Architecture and Civil Engineering
Published: November 2023

The article considers the problems of using existing mathematical models (Mohr-Coulomb, Hardening Soil, Soft Soil) for calculating bases of soft soils of the lacustrine-glacial complex lg III. In addition, in geotechnical calculations there has developed the practice of forming local soil models taking into account the features of a particular region. A detailed study of the physical and mechanical properties of soils is a necessary aspect for the validation of models in software systems. In this regard, the authors have carried out a study of the weak clayey water-saturated soil of St. Petersburg to regulate the program of its laboratory tests and values for mathematical models in the regional geotechnical software systems.
Evaluation of the Antibacterial and Anti-Adherent Activities of Eucalyptus globulus and Eucalyptus citriodora Essential Oils against Pseudomonas aeruginosa Strains
Authors: Ribeiro Ana Beatriz Bomfim Gomes , Guimarães Fernandes Viton Dyrk , Moreira de Oliveira Nóbrega Lara Mayanne , Rocha Lima Santos Vinícius , De Lima Ferreira André , Simões Lira Antônio Matheus , Grangeiro Leite Bezerra Vinicius , Gomes Pereira da Silva Roberta , Da Silva de Oliveira Vinicius , Lima Filho Amaro , Mendonça dos Anjos Raline , Alves de Oliveira Filho Abrahão
Published: November 2023

Biofilm can be defined as a complex sessile microbiological ecosystem formed by one or more species of bacteria, fungi or protozoa. Among the microorganisms capable of forming biofilms is Pseudomonas aeruginosa, a gram-negative bacterium with extensive virulence factors and high resistance to antimicrobials, making it difficult to treat infections caused by it. In this sense, phytotherapy and essential oils are promising therapeutic alternatives to multi-resistant microorganisms. The aim of this study was to evaluate the antibacterial and anti-adherent activities of Eucalyptus globulus and Eucalyptus citriodora essential oils against clinical strains of P. aeruginosa, and to compare their antibiofilm effects with 0.12% chlorhexidine digluconate. To determine the Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) of the oils, the broth microdilution technique was used in 96-well plates. To determine the Minimum Adherence Inhibitory Concentration (MAIC), the inclined glass tube technique was used in the presence of 5% sucrose, using proportions corresponding to the pure essential oil up to a dilution of 1:1024, and its positive control was 0.12% chlorhexidine digluconate. It was therefore concluded that the essential oils under study had an antibacterial effect against the strains tested, varying between bactericidal and bacteriostatic action, as well as demonstrating an effective anti-adherence effect that was superior to the positive control.
PENGARUH UPAH MINIMUM DAN PENDIDIKAN TERHADAP PRODUKTIVITAS TENAGA KERJA DI KOTA MEDAN
Authors: Rozaini Noni , Ramadhana Muhammad Fitri , Irwansyah Irwansyah , Sinaga Marcell E R
Published: November 2023

Penelitian ini bertujuan untuk mengetahui pengaruh upah minimum dan pendidikan terhadap produktivitas tenaga kerja di Kota Medan. Jenis penelitian ini adalah penelitian kuantitatif. Jenis data dalam penelitian ini adalah data runtut waktu (time series) yaitu data dari tahun 2008 sampai dengan tahun 2022. Sumber data yang digunakan bersumber dari Badan Pusat Statistik Kota Medan (BPS Kota Medan). Teknik analisis data yang digunakan merupakan analisis linier berganda,  menggunakan bantuan perangkat lunak E-views 12 dengan metode (Ordinary Least Square). Hasil data secara parsial mengatakan variabel upah minimum berpengaruh positif terhadap produktivitas tenaga kerja, sedangkan tingkat pendidikan tidak berpengaruh terhadap produktivitas tenaga kerja. Secara simultan variabel upah minimum dan pendidikan bersama-sama mempengaruhi produktivitas tenaga kerja. Kata kunci: Upah minimum, Pendidikan, dan Produktivitas Tenaga Kerja
PENGEMBANGAN BAHAN AJAR BERBASIS PROJECT BASED LEARNING MATA KULIAH PERILAKU KONSUMEN FE UNIMED
Authors: Putriku Aurora Elise , Silaban Putri Sari M.J. , Manullang Randeska
Published: November 2023

Mata kuliah Perilaku Konsumen merupakan salah satu mata kuliah yang terdapat dalam program studi pendidikan bisnis yang dirancang agar para lulusan Prodi Pendidikan Bisnis dalam memahami bagaimana perilaku konsumen dalam dunia nyata, sehingga menjadi bekal ilmu bagi para lulusan dalam pengelolaan bisnis. Model pembelajaran Project Based Learning adalah model pembelajaran yang memperkenankan peserta didik untuk bekerja mandiri maupun berkelompok dalam mengkonstruksi pembelajarannya dan mengaplikasikannya dalam produk nyata. Secara umum penelitian ini bertujuan mengetahui tingkat kelayakan dan efektifitas  bahan ajar berbasis Project Based Learning pada mata kuliah Perilaku Konsumen Program Studi Pendidikan Bisnis Universitas Negeri Medan dapat meningkatkan hasil belajar mahasiswa. Jenis Penelitian yang digunakan adalah penelitian dan pengembangan dengan model Analysis, Design, Development, Implementation, and Evaluation (ADDIE). Buku ini telah divalidasi oleh 3 orang validator dan hasilnya menunjukkan bahwa buku tersebut memiliki kelayakan yang tinggi namun perlu dilakukan revisi. Setelah merevisi buku, uji coba dilakukan pada kelompok kecil yang terdiri dari 30 mahasiswa semester 5 yang mengambil mata kuliah Perilaku Konsumen . Berdasarkan hasil tes, nilai post-test siswa lebih tinggi dari hasil pre-test.