bluuebunny/crossref_metadata_2025 huggingface dataset:
PANCREATIC INTERNAL FISTULA - AN EXPERIENCE FROM A TERTIARY CARE CENTRE
Authors: K. Prasad Abilash , Kumar P Suresh , Sankar Subramanian
Published: September 2023

Pancreatic ascites and pancreaticopleural effusion are known
as internal pancreatic fistulas and result from disruption of
the pancreatic duct or leakage from a pseudocyst. Internal
pancreatic fistula (IPF) are an uncommon but well-recognized
complication of chronic pancreatitis (CP) that are associated
with significant morbidity and mortality(1).Alcohol-related
CP is considered the main cause of IPF. It is a distinct clinical
entity characterised by markedly elevated levels of amylase
and protein levels in the ascitic or pleural fluid. As many
patients are alcoholics, IPF is often misdiagnosed
initially.Many patients are wrongly diagnosed as cirrhotic
ascites or tuberculous ascites or tuberculous effusion or
peritoneal carcinomatosis (2). Hence recognition of this
distinct clinical entity is important.
A QUALITATIVE STUDY OF COMMUNITY HEALTH OFFICERS' EXPERIENCES WITH
TELEMEDICINE IN A RURAL BLOCK OF MADHYA PRADESH
Authors: M Ananthakrishnan , C.M Chaitra
Published: September 2023

Telemedicine implementation in Health and Wellness Centers facilitates consultation, screening and remote
monitoring, allowing individuals to connect with health care providers, receive medical advice and promote wellness.
This will improve access to specialists, support follow-up care, especially for patients with chronic diseases, and
ultimately improve access to healthcare and better outcomes. Methods: Twenty-two semi-structured interviews with
Community Health Officers working in a rural block of Madhya Pradesh were conducted and analyzed using thematic
analysis to assess their perspectives regarding the benefits and challenges of telemedicine. Results: Community
Health Officers identified several advantages and challenges related to Telemedicine.Telemedicine offers promising
opportunities to transform rural healthcare, enhancing accessibility, convenience, and patient-centred care. However,
challenges in technical aspects,patient assessment,and data privacy must be addressed through appropriate training,
policy frameworks, and patient education. Conclusions: Telemedicine ensures that patients in remote areas receive
necessary and desired care, offering convenience and timely medical advice without disrupting daily activities.
However, addressing technical challenges and privacy concerns while providing specialized training to healthcare
providers can maximize its effectiveness and bridge the healthcare access gap for underserved populations
COMPARATIVE STUDY OF SHORT TERM OUTCOMES OF LAPROSCOPIC VERSUS OPEN VENTRAL ABDOMINAL WALL HERNIA MESH REPAIR EXCLUDING GROIN ( INGUINAL AND
FEMORAL ) HERNIA IN TERTIARY CARE HOSPITAL.
Authors: S. Karmarkar P. , Ghuge Kiran , Bhat Gautham
Published: September 2023

Aims and objectives:
Primary: To compare perioperative complication of open repair with laproscopic repair of ventral hernia i.e
1. Tissue or organ damage ( bowel , bladder )
2. Surgical site infection
3. Wound seroma / hematoma
4. Wound dehiscence/ gap
5. Postoperative pain
Secondary: To analyze and compare the parameters of
1.Duration of surgery
2.Postoperative hospitalization stay
3.Mortality / morbidity
4.Age
Methods:
Patients admitted from MARCH 2021 to FEBRUARY 2022 with ventral abdominal hernia excluding groin ( inguinal and
femoral ) hernia in department of general surgery , in a tertiary care hospital are included in study . by systemic random
sampling those patient divided in two group
(A)Group : Patients who are considered for laproscopic ventral hernia repair
(B)Group : Another group of patients who are considered for open ventral hernia repair
Result: Postoperative pain and length of hospital stay is significantly less in laproscopic ventral hernia repair. Post
operative complication like wound infection , seroma and hematoma were relatively less in laproscopic group.
THE MUTUAL FUND SUBSCRIPTION AND REDEMPTION IMPACT ON EQUITY MARKET DURING COVID-19– A STUDY
Authors: Ratnaraju P.
Published: September 2023

The present study has been emphasized on the role of mutual fund subscription and redemption in Indian equity market
during covid-19.The study has considered the data from the year 2011 to 2022.The VIX index has been considered to
know the impact of mutual fund subscription and redemption on market volatility during covid-19.The ARCH model has
been applied and the result states that the VIX is getting influenced by the subscription and redemption amount of
mutual funds. The ordinary least square method result indicated that the mutual funds subscription and redemption
impact is observed on the Indian equity market capital during covid-19.This study is useful the equity retail investors,
mutual funds AMC's,regulators and other market stake holders.
TINY BUT DEADLY: A THREAT TO ENVIRONMENT
Authors: Hegde Vijaya , S Megha
Published: September 2023

Cigarette butts are small which tend to go unnoticed. It is the common form of plastic pollution. It contains hundreds of
toxic chemicals, which when released can be a serious threat to us and to our environment. The theme of World No
Tobacco Day 2022 is “Tobacco: Threat to our environment.” This puts our focus on cigarette butts. Hence the aim of this
study was to analyse the metals leached out from cigarette butts. The objectives was to quantify and compare metals
leached out from the filter part of the cigarette butts and the whole cigarette butts. The methods followed was the
cigarette butts were collected from smokers. Following collection, Cigarette butts and only the filter part of the cigarette
butts were added separately to aqueous solution of 50 ml of concentrated HCL in deionized water. pH of the solution was
adjusted to 6. It was allowed to soak for 24 hours. The trace metals concentration from the resultant leachate was
estimated using Inductively Coupled Plasma Optical Emission Spectroscopy (ICP-OES). From the results, Metals such as
Al (4.2 ppm), Cu (5.5 ppm) and Sr (3.6 ppm) were identified from the leachates of filter part of the butt alone and metals
such as Ba (9 ppm), Fe (3 ppm), Sr (31 ppm), Cu (8 ppm), and Al (17 ppm) were identified from the leachates of whole
cigarette butt. The study concludes that multiple metals are released from the butts which can be a potential source of
threat to the humans and to the environment.
Pastoralist Transhumance and Conflicts in the Sahelian zone of the Nigeria-Niger Borderlands
Authors: Aliyu Shuaibu Shehu , Sama’ila Abubakar
Published: September 2023

Pastoralism has been an old practice in the Sahel region of West Africa. In recent years, pastoralists in Nigeria have increasingly been migrating on seasonal transhumance southward from the neighboring countries especially Niger Republic in search of better grazing conditions. This has increased pressure on farmlands which instigate farmer-herder conflicts. These conflicts occur mainly between farmers and pastoralists, but also between pastoralist groups themselves. However, there has been a shift in these conflicts recently to involve traditional institutions and in some cases the local authorities along the borderlands. The involvement of local institutions in the conflict has created an incentive for local actors, particularly pastoral community-based groups in responding to these violent threats. As pastoralists are mobile, these conflicts became difficult to contain and thus, spill across borders. Consequently, the conflict has now transformed into an urbanized regional conflict that involves some major cities along the Nigeria-Niger borderlands; Sokoto, Zamfara, and Katsina on the Nigerian side and Dosso, Tahoa, and Maradi in the Niger Republic. These areas are now experiencing an unprecedented growing wave of violence that has become complex and escalated into a hydra-social conflict. This research aims to investigate how the fluidities of the Nigeria-Niger borderland intensified armed conflicts between the local pastoral organizations and the sedentary population spreading to some urban cities along the borderlands.
The Effect of COVID-19 Vaccine on Hematological Parameters and Kidney Function
Authors: Jasim Ridhab Ajeel , Al-Obaidi Fiham Jassim , Noori Saif Subhi , Mahmood Adeeb Shakir
Published: September 2023

The 2019 coronavirus disease (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused an extraordinary setback in the global economy and public health. Vaccination is one of the most effective measures to significantly reduce severe illness and death from COVID-19. In recent years, there have been an increasing number of reports of new acute kidney injury (AKI) following COVID-19 vaccination. Podocyte injury, IgA nephropathy, vasculitis, tubulointerstitial injury, and thrombotic microangiopathy are considered to be the major pathological phenotypes. Nevertheless, whether the association between COVID-19 vaccination and acute kidney disease (AKD) is causal or chance remains to be tested. Indeed, it is undeniable that mass vaccination against COVID-19 will bring significant benefits in preventing morbidity and mortality from COVID-19. The study included the effect of the Corona vaccine on kidney functions and blood variables MCV, HGB, among vaccinated adults aged (18-32) years in Anbar province, auditors Ramadi Teaching Hospital and Anah General Hospital.40 blood samples were collected and a test was conducted for blood variables and kidney functions (creatinine and urea), and it was found that the percentage of urea and creatinine has increased among the vaccinated compared to its percentage when the unvaccinated, and that the percentage of MCV, HGB decreased among the vaccinated compared to the unvaccinated, as the study showed that the percentage of urea was among the unvaccinated (21.7) while among the vaccinated (36.41). Creatinine was among the unvaccinated (0.695) while among the vaccinated (1.041). The MCV rate among the unvaccinated (85.86) while among the vaccinated (82.74) and the percentage of HGB among the unvaccinated (13.58) while it was among the vaccinated (12.37).
Understanding the Multifaceted Dimensions, Socio-psychological Aspects, and Current Practices of Inclusive Education in Nepal: A Comprehensive Analysis
Authors: Kunwar Rajendra , Adhikari Sapana
Published: September 2023

This study offers a comprehensive analysis of the multifaceted dimensions, socio-psychological aspects, and practices of inclusive education in Nepal. Inclusive education aims to provide equitable opportunities for all learners, regardless of their backgrounds, abilities, or disabilities. This study sheds light on the challenges and opportunities in promoting inclusive education in Nepal. Additionally, the socio-psychological aspects of inclusive education, including fostering a sense of belonging, respect for diversity, and social integration, are explored. The analysis is based on a thorough review of existing literature, observations, and informal discussions with educational authorities, teachers, parents, and students, as well as the researcher's personal experiences in the field. The findings of this study contribute to a comprehensive understanding of inclusive education in Nepal and provide insights to inform policy formulation, curriculum development, and effective implementation of inclusive practices. Ultimately, this study underscores the importance of inclusive education in building an inclusive and harmonious society in Nepal.
Is there any Good Model for the Happy Life of the Husband and the Wife? Yes, there is a Model. - My Loving Husband! Give me (Your Wife) the Power on the Comfortable State! (Tcheonzamun 721st-736th)
Authors: Kim Sangdeog Augustin
Published: September 2023

French Missionary Dallet (1874) introduced about ‘The thousand character essay’ in his book. ‘The thousand character essay’ is called in Korea as ‘Tcheonzamun’ (Han, 1583). Is it possible to say about the marriage life? Is there a good model for the life of the husband and the wife? Here, the author of ‘The thousand character essay (Tcheonzamun)’ wants to say about this matter of marriage life. There are two methods for the translation of ‘The thousand character essay’. The first method is translation through Korean pronunciation of Chinese characters on the Tcheonzamun poem (Park et al., 2021b). And the second method is through the meaning of Chinese character on the Tcheonzamun poem (Park et al., 2021a). Additionally, the deleting method is carried out. This is the work of translation of Tcheonzamun poem (721st-736th). The title of this work is ‘Is there any good model for the happy life of the husband and the wife? Yes, there is a model. - My loving husband! Give me (your wife) the power on the comfortable state! - 索(Swi) 居(ge) 閑(han) 處(Tchae), 沈(Si) 默(meul) 寂(Zwo) 寥(yo) (Tcheonzamun 721st-736th)’.
Hashimot's Thyroditis: Immunopathogensis, Antibody-Associated and Risk of Malignancy
Authors: Majeed Maha Sabah , Hashim Ali Fadhil
Published: September 2023

Hashimoto's thyroiditis (HT) is considered as one of the most common immunological disorders influencing the thyroid gland. This disorder affect mostly the middle aged people especially the female inspite that there is no age group exclusion. It is a common cause of hypothyroidism. It was clearly that HT is correlated with thyroid cancers especially papillary thyroid carcinoma and lymphoma. In this article we tried to focus the main points of immunopatho- genesis, differential diagnosis and cancer association.
Fibrolamellar Hepatocellular Carcinoma in Young Adult: A Case Report and Literature Review
Authors: Lopez Alexis Jared Paz , Salas Brenda Aurora Llanos , Hernandez Michel Vladimir Alamo , Ruiz Emmanuel Stephano Bracho , Cardenas Greta Griselda Reyes , Martinez Javier Martinez , Covarrubias Andrea Cecilia Muñoz , Cardenas Alian Guzman
Published: September 2023

Fibrolamellar carcinoma (FLC), a truly unique and uncommon variation of hepatocellular carcinoma (HCC), accounting for barely 1%–9% of all HCC cases. Fibrolamellar carcinoma, an unclear malignancy, appears to be more commonly observed in youthful individuals without any preexisting liver conditions. The nomenclature "fibrolamellar" originates from the presence of dense fibrous collagen bands enveloping the neoplastic cells. Contrary to hepatocellular carcinoma (HCC), cirrhosis and viral hepatitis infection do not serve as predisposing factors for fibrolamellar carcinoma (FLC). Additionally, FLC is not typically associated with increased levels of serum alpha-fetoprotein. Patients with FLC frequently manifest with nonspecific abdominal discomfort, queasiness, general discomfort, and decreased in body mass. Surgical intervention, specifically resection or liver transplantation, serves as the cornerstone of treatment and represents the sole potentially curative avenue. FLCs, or fibrolamellar carcinomas, have historically exhibited lower responsiveness to chemotherapy compared to conventional hepatocellular carcinomas (HCC). Nevertheless, it is important to note that in cases of advanced FLCs, the utilization of multi-modality treatments has shown promising effectiveness. The purpose of this review is to explain the clinical characteristics, diagnostic techniques, and therapeutic approaches for this uncommon tumor in order to enhance the knowledge of healthcare professionals.
Epithelial-Myoepithelial Carcinoma of the Palate on Pleomorphic Adenoma: Case Report and Review of the Literature: Experience of the Oncology-Radiotherapy Department of the Mohammed VI University Hospital, Marrakech
Authors: Slitine Dalila Sounny- , ElAlouani Chahrazade , Berrada Sophia , Elkadiri Ouassima , Ousalm Raja , Darfaoui Mouna , Omrani Abdelhamid El , Khouchani Mouna
Published: September 2023

Epithelial-myoepithelial carcinoma (EMC) is a rare malignant tumor of the salivary glands, mainly affecting the parotid gland. Its association with a pleomorphic adenoma is exceptional. We report the case of a 64-year-old Moroccan woman with a pleomorphic adenoma of the palate that had been evolving for several years. The recent increase in the mass associated with the appearance of homolateral cervical adenopathies led us to think of a malignant transformation. Final histological examination after resection of the mass showed an unexpected association of a pleomorphic adenoma and EMC. EMC is a low-grade malignant tumor. It can arise de novo or on a pleomorphic adenoma. Malignant transformation of the adenoma is suspected when the volume of the adenoma increases rapidly, with the appearance of cervical adenopathy. However, these clinical changes may herald the appearance of a distinct tumor. Despite its tendency to local recurrence and low metastatic potential, rare cases of EMC may exhibit aggressive behavior and distant metastases. Treatment consists mainly of complete surgical resection if possible, followed by radiotherapy to prevent local recurrence, and this is the treatment our patient received in this case.
Understanding the Dynamics of Multi-Dimensional Poverty Index: BIMARU States: An Econometrics Approach
Authors: Srivastava Vikas Deepak , Kumar Vijay , Srivastava Prabhu Narayan
Published: September 2023

The research study analyzes multidimensional poverty in seven states of India, namely Bihar, Chhattisgarh, Jharkhand, Madhya Pradesh, Odisha, Rajasthan, and Uttar Pradesh. The study focuses on three key dimensions of poverty: infant mortality rate, birth rate, and educational dropout rates at both primary and upper primary levels. Additionally, the study examines the availability of basic amenities such as clean cooking fuel, improved sanitation facilities, and safe drinking water. By calculating the Multidimensional Poverty Index (MPI), the study ranks the states based on their performance in these dimensions. Madhya Pradesh emerges as the top-performing state with the lowest MPI score of 0.310745, followed by Uttar Pradesh, Rajasthan, Chhattisgarh, Odisha, Bihar, and Jharkhand. The study reveals that despite having relatively low MPI scores, Madhya Pradesh and Uttar Pradesh still struggle with high infant mortality rates and birth rates. This indicates the need for targeted interventions to improve healthcare and family planning services in these states. Additionally, the study highlights the importance of education in poverty reduction. It identifies Jharkhand and Chhattisgarh as states with the highest primary and upper primary education dropout rates. This emphasizes the need for improving the quality of education and implementing strategies to encourage school completion. It also states the importance of addressing issues related to healthcare, education, and basic amenities in order to reduce poverty and improve overall well-being. The normalized index approach used in this study provides a comprehensive and objective measure of poverty, enabling policymakers and stakeholders to make informed decisions and allocate resources effectively.
Prevalence of Depression and Patterns among Adult Hypertensive Patients Attending a Primary Care Clinic in South-South, Nigeria
Authors: C Dickson I. , C Imarhiagbe O. , A Grend E. , A Wifa-Oweredaba N. , N Nwanze M. , J Yoko I, Ikurayeke , N Elenwo M. O. , F Famba D. , J Sokolo E. , I Amaechi G.
Published: September 2023

Depression is a chronic mental illness, an important health problem and a leading cause of ill health and disability worldwide. Depressed patients present with a depressed mood, loss of interest in pleasurable activities, decreased energy, feelings of low self-worth or guilt, appetite or sleep disturbances, and poor concentration. Depressive symptoms are common in chronic medical illnesses like hypertension but are not recognized and treated. This study evaluated the prevalence and pattern of depression among hypertensive patients in a primary care clinic in South-South, Nigeria. This is a descriptive cross-sectional study involving 312 adult hypertensive patients attending the Family Medicine clinic of the Rivers State University Teaching Hospital, Port Harcourt selected by a systematic random sampling method. A specially designed questionnaire was used to record participants' characteristics and Patient Health Questionnaire 9 was used to evaluate for depressive symptoms. The data collected were analysed using the statistical package for social sciences (SPSS) version 20. The study lasted for 3 months and ethical approval was obtained from the ethical committee of the Rivers State University Teaching Hospital. The study showed that the prevalence of depression was 26.6%. The respondents with ages ranging between 50 – 59 years had the highest frequency of depression, 30.1% (25). More female respondents 71.1% (59) were depressed. The highest proportion of the respondents that were depressed 42.2% (35) had secondary education. More than half of the depressed respondents were married 57.8% (48). More than half of the respondents, 62.7% (52) had a monthly income below ₦50,000.
The Influence of Lecturers' Persuasive Communication on Self-Confidence and Learning Motivation of Buddhist College Students
Authors: Gautama Sidartha Adi , Seneru Wistina , Widiyanto Widiyanto , Andriyaningsih Ayu , Yudhawati Ine
Published: September 2023

This quantitative research aims to determine the contribution of lecturers' persuasive communication to students' self-confidence and learning motivation. The study population was students of Jinarakkhita Buddhist College of Lampung. The sampling technique was carried out by random sampling with the number of selected samples as many as 78 people. The research data were collected using the lecturer's persuasive communication scale, self-confidence scale, and learning motivation scale. The data analysis technique used was multivariate analysis of variance (MANOVA). Analysis of research data showed that there was a positive contribution between persuasive communication and self-confidence. It is also known that there is a positive contribution between persuasive communication and learning motivation. Specifically, it is known that in this study, lecturers' persuasive communication is high, students' self-confidence is moderate, and students' learning motivation is also moderate.
Manajemen Strategis PP. Avia Avian Tbk
Authors: Santoso Elvina Yohana
Published: September 2023

Strategic management is a crucial approach for organizations in facing a dynamic changing business environment. PT. Avia Avian Tbk, as a company operating in an industry, faces diverse challenges and opportunities in a rapidly changing environment. This study aims to analyze the strategic management approach implemented by PT. Avia Avian Tbk in facing market and technology changes. This research uses qualitative analysis methods by conducting an in-depth review of the company's documented strategy and interviews with key stakeholders in the company. The results showed that PT. Avia Avian Tbk has adopted a strategic management approach that focuses on [e.g. product differentiation, operational efficiency, new market penetration, or technological innovation]. These strategic steps are geared towards maximizing value for the company's stakeholders, including shareholders, customers, employees, and society. One of the important aspects in the strategic management of PT. Avia Avian Tbk is the use of environmental analysis tools such as PESTEL (Political, Economic, Social, Technology, Environmental, Law) to identify external factors that may affect their business. In addition, the company has also set measurable long and short-term goals, and implemented performance measurement and monitoring mechanisms to ensure the achievement of these goals. Overall, this study provides insight into the strategic management approach applied by PT. Avia Avian Tbk and how the company strives to optimize its business performance in the midst of a changing business environment. The research also provides a foundation for other companies in similar industries to understand best practices in dealing with similar challenges.
Peningkatkan Kemampuan Guru Menyusun Rpp Melalui In House Training
Authors: Sarno  , Mulyono Rahmat
Published: September 2023

The purpose of this research is, "How are the efforts of the Principal to improve the ability of teachers in preparing lesson plans through In House Training (IHT)". In House Training (IHT) is a training program that is held at the training participant's place or at school by optimizing the potentials that exist in the school, using the trainee's work equipment with relevant material and the problems being faced, so it is hoped that participants can more easily absorb and apply the material to solve and overcome the problems experienced and be able to directly improve the quality and performance. In House Training (IHT) is carried out to improve teacher performance in accordance with their field of work by utilizing the potential that exists in an organization or institution. The results of InHouse Training (IHT) in compiling lesson plans in cycle I were still low, the teacher's score percentage reached 53.63. It is still far from the target planned in the research of 80. Even though there are actually only two aspects that have not been filled in, the aspects that have been filled in are not complete. For this reason, the research was continued in cycle II with several improvements. After conducting In House Training (IHT) in cycle II, there was an increase in competence in preparing lesson plans, implementing learning, and implementing process assessments (preparation of lesson plans) in accordance with Permendiknas Number 41 of 2007. Of the three aspects that were the focus of InHouse Training (IHT), all teachers who were the subject of the study experienced an increase.
Kualitas Hard Skill Mahasiswa Trainee Departemen Front Office pada Hotel Bintang Empat di Kota Bandung
Authors: Zahra Retha Syahvina , Octaviany Vany
Published: September 2023

Most of the Human Resources in the Hospitality Industry, particularly in the Front Office department, have limitations in terms of knowledge, competence, and technical skills in their work. This requires efforts to enhance their understanding of these aspects in their work, in order to improve the quality of the services provided and ensure the smooth operation of the hotel. The aim of this research is to determine the quality of hard skills of student trainees in the Front Office department at a four-star hotel in the city of Bandung and the efforts to enhance these skills. The method used is qualitative ethnography, involving observation, documentation, and interviews with the Front Office Manager (FOM), supervisors, and student trainees at the four-star hotels. The research locations include Four Points by Sheraton, The Jayakarta Hotel Bandung, and Grand Tjokro Hotel. Based on the analysis results, it was found that hard skills are formed through interactions between technical abilities, knowledge, and technological proficiency. Overall, this study found that student trainees have good knowledge, technical skills, and technological abilities in their work. Efforts to enhance the hard skills of student trainees in the Front Office department include providing training to improve additional skills such as time management, interpersonal communication, and problem-solving.
The Prognostic Nutritional Index in prediction of two-year mortality in patients undergoing Transcatheter Aortic Valve Replacement
Authors: Ozilhan Murat Oguz , Açıkgöz Sadık Kadri
Published: September 2023

Objective: Transcatheter aortic valve replacement (TAVR) is a minimally invasive procedure employed to treat aortic valve disease in patients who are ineligible for open-heart surgery. Undergoing TAVR patients generally include the elderly and frail. Malnutrition is associated with high morbidity and mortality in patients with undergoing TAVR. The aim of this study was to investigate the prognostic value of the prognostic nutritional index (PNI) for two-year survival after TAVR.
Material and Methods: A cohort of 213 consecutive patients with severe aortic stenosis who underwent transcatheter aortic valve replacement between March 2019 and July 2021. The study population was divided into two groups according to the cut-off PNI level in a receiver operator characteristic (ROC) curve analysis. The two-year follow-up results of the patients were recorded retrospectively. PNI was defined according to the following formula: PNI = (10 x serum albumin [g/dl]) + (0.005 x total lymphocyte counts [1000/mcL]).
Results: Mean age of the patients was 76.15, and 93 (43.7%) of them were males. Patients with low PNI (group 1) were significantly older. The mean PNI of group 1 was 43.17 ± 4.04 and the mean PNI of group 2 was 54.23 ± 4.30. Mortality at two-year was 32.6% in low PNI group and 10.7% in high PNI group. Hypertension and PNI were independent predictors of mortality after TAVR. In ROC curve analysis, PNI at a cut off value of 48.325 predicted the mortality after TAVR with 63.5% sensitivity and 70.1% specificity. Kaplan-Meier curves for two-year mortality between low and high PNI groups showed worse outcomes in patients with low PNI.
Conclusion: PNI is a practical and useful nutritional index that predicts two-year mortality after TAVR.
Exploring the Interplay of Hypoxia-Inducible Factors: Unveiling Genetic Connections to Diseases Through Bioinformatics Analysis
Authors: Kivanc Izgi Demet , Oguz Suleyman Rustu
Published: September 2023

Objective: Hypoxia-inducible factor (HIF) is a transcription factor that is effective in the ability of cells to sense and adapt to changes in oxygen levels. HIF1α gene is located in the 14q23.2 chromosome region and consists of 15 exons and 14 introns. It is a transcriptional regulator of metabolic processes such as angiogenesis and erythropoiesis and is required for immunological responses.
Material and Methods: Our study examined the function of HIF1α and its relations with other genes and diseases using various bioinformatics database tools. GENEMANIA/GeneCard databases were used to detect the relationship of HIF gene with other genes, miRDB to show target miRNAs, STRING to detect protein-protein interaction, and GWAS databases to show its relationship with diseases. In addition, organs and tissues in which it is expressed were determined using the UniProt database.
Results: The bioinformatic analysis yielded significant results, revealing that 189 miRNAs target HIF1α and exhibits close interactions with 10 genes, among which important genes like STAT3, MDM2, TP53, SMAD3, and VHL were identified. The most predominant pathway utilized by the HIF1α gene was determined to be the HIF-1 signaling pathway. A co-expression relationship was also established with proteins EPO, PLIN2, BNIP3, and the enzyme ENO1. Furthermore, it was ascertained that HIF1α exhibits the highest expression levels in the kidney and the perivenous region of the liver. Moreover, close associations have been established between HIF1α and diseases such as renal cell carcinoma and bladder cancer.
Conclusion: Identifying the pathways associated with HIF1α, other genes, and epigenetic factors with the help of Bioinformatics Tools may enable experimental studies to be carried out with large cohorts and using a broad perspective. Thus, it may contribute to our understanding of how this gene affects diseases and anomalies and to accelerate the studies of targeted therapeutic treatment.
ANNOTATING TRANSLATION AS A MEANINGFUL METACOGNITION-ORIENTED PRACTICE IN THE TRANSLATION CLASSROOM
Authors: Costa Cynthia Beatrice , Lourenço da Silva Igor Antônio
Published: September 2023

Translating is a cognitively complex activity aimed at tackling an ill-defined problem: selecting only one viable rendition in the target language from a series of multiple viable choices for a given text in a source language (PYM, 2003). Developing the ability to perform such an activity with a reasonable speed and justified confidence (PYM, 2003) may profit from learning how to perform a parallel activity, i.e., annotating, as a fruitful avenue toward metacognition (ALVES, 2005; SHREVE, 2006) and the articulation thereof. We argue in this article that annotating (or commenting) can be an effective practice in the translation of any genre and play a relevant role from the beginning of translator’s training. Building both on a review of expertise (ERICSSON, 2001) and translation pedagogy (GONÇALVES, 2020; ESQUEDA, 2020) and on our own teaching experience, we suggest that annotating translation can: a) be performed as part of deliberate practice (in the broad sense) during the translation process, b) honestly inform students and trainers about the difficulties faced during the process, c) invite useful feedback, and d) potentially leverage students’ metacognition.
DESAFIOS E PERSPECTIVAS NA TRADUÇÃO DO POEMA THE TEMPLE OF NATURE, DE ERASMUS DARWIN
Authors: De Masi Gabriel , de Almeida Navarro Eduardo
Published: September 2023

Erasmus Darwin (1731-1802), avô de Charles Darwin (1809-1882), foi médico, naturalista, engenheiro, filósofo e poeta, tendo gozado de grande prestígio nos círculos intelectuais britânicos da segunda metade do séc. XVIII. Escreveu dois grandes poemas, The Botanic Garden (1789) e The Temple of Nature (1803), nos quais expunha ideias científicas ousadas e originais, incluindo uma teoria a respeito da origem da vida e da transformação das espécies que encontrará ecos no pensamento do neto. Amálgama de ciência e literatura, sua poesia constitui-se importante representante da mentalidade iluminista que caracterizou esse período da Europa ocidental. A tradução de sua poesia descobre uma série de desafios: no plano formal, impõe-se a questão, já muitas vezes debatida, da possibilidade de recriação do pentâmetro iâmbico. No campo lexical, a dificuldade reside no extenso vocabulário técnico de Erasmus – terminologia botânica, médica, geológica, etc. Apresentando um excerto do Canto II, procuramos discutir problemas e soluções encontrados ao longo da tradução de seu poema The Temple of Nature, bem como comentar a variedade de ideias nele apresentadas.
Faktor Risiko Keluhan Subjektif Kejadian Keracunan Petani Sayur di Desa Plaosan Kabupaten Magetan
Authors: Dwi Nurcahyo  , Vincentius Supriyono  , Aries Prasetyo  , Sujangi
Published: September 2023

Chemicals and other materials in the form of jasad renik and viruses are used to prevent or eradicate pests that can damage plants. They are usually called pesticides. Some plants or agricultural products that stimulate plant growth kill some plants without fertiliser and prevent unwanted growth. Severe poisoning refers to low-level long-term effects or exposure to toxic substances, such as frequent spraying of pesticides during dangerous spraying times. The effects of chronic exposure do not appear immediately after the first exposure; it takes a long time for symptoms to appear. Plaosan is one of the villages and sub-districts in Magetan district where part of the population works as vegetable farmers. The population in Plaosan village is 5,678 people spread over 5 hamlets, namely Gulun, Duwet, Kauman, Sale, and Kandenan. To increase optimal agricultural yields, farmers in agricultural intensification usually use pesticides. Pesticides continue to accumulate in the body and slowly damage the tissues. People who are frequently exposed to this pesticide at low doses may suffer from symptoms of poisoning long after their initial exposure. Chronic symptoms include chronic oral inhalation poisoning and chronic skin contact. This research uses a descriptive type of research. Descriptive research is a study that describes the magnitude of the problem under study. Descriptive research is research with the main objective of making an objective picture or description of a situation. This study aims to determine the risk factors for subjective complaints of pesticide poisoning of vegetable farmers in the work area of the Plaosan Health Centre in terms of individual factors, behaviour, environment, and pesticide use. The results of this study regarding the risk factors of subjective complaints All farmers experienced complaints of severe, moderate, and mild health complaints, including headaches, dizziness, nausea, vomiting, a weak body, nervousness, trembling, blurred vision, sweating a lot, a fast heart rate, and difficulty breathing.
CFD analysis of hydrodynamic force on a horizontal axis tidal turbine
Authors: Xu Kai , Finnegan William , O’Rourke Fergal , Goggins Jamie
Published: September 2023

Horizontal axis tidal turbines are similar to wind turbines in both geometry and principle of operation, yet they need to withstand much heavier loadings and extreme conditions in a harsh operating environment. Consequently, the loadings on tidal turbine blades need to be accurately evaluated within the design stage to ensure they can withstand loadings with little need for repair. With the advancement of computational capabilities, computational fluid dynamics offers a relatively inexpensive method of simulating working conditions and estimating loadings, compared to traditional physical testing, while maintaining accuracy and applicability under a range of operating conditions. In this research, a computational fluid dynamics model of a tidal turbine rotor has been developed using commercial code ANSYS CFX, where the three-dimensional blade geometry is developed from the prototype tidal turbine used in the Round Robin Tests in the framework of the H2020 MaRINET2 Infrastructures Network project. The outputs from the numerical model are validated against the experimental results, where it is revealed that with an increasing rotating speed of the tidal turbine, the thrust force that turbine experienced increases, while the torque force experiences a rise firstly, reaching a maximum value and then decreases gradually. In addition, the experimental results show that during the operation of ocean tidal turbines, the turbine blades experience frequent and large-scale fluctuation of hydrodynamic loads, including thrust and torque, which may lead to tidal turbine blade damage due to fatigue. Therefore, the next stage of development with this numerical model is fatigue loading evaluation, in order to improve the present fatigue design and testing of tidal turbine blades, while gaining a greater understanding of the damage mechanisms.
Numerical modelling of a box-type and bottom-detached oscillating water column wave energy conversion device: a comparison with experimental data and between BEM and CFD numerical modelling
Authors: Raghavan Vaibhav , Simonetti Irene , Lavidas George , Cappietti Lorenzo
Published: September 2023

Utilization of Boundary Element Method (BEM) based on linear potential flow for modelling Oscillating Water Column (OWC) devices has gained popularity in the last two decades. The commercial BEM solver WAMIT has been used widely for modelling OWCs and validated using experimental modelling (Delauré et. al. 2003, Bingham et. al. 2015, Faÿ 2020). The open-source BEM solver NEMOH has however been mostly ineffective in modelling OWCs since the main approach adopted previously modelled the imaginary piston as a thin disk. In this research, the multi-body interaction problem has been adopted in modelling a box-type and bottom-detached OWC device in NEMOH, where the imaginary piston has been modelled to the length of the internal water column (Penalba et.al. 2017) and compared with experimental data. A further comparison is drawn with the numerical method of Computational Fluid Dynamics (CFD) , which has shown to be accurate for modelling OWC devices (Simonetti et. al. 2015), yet requires significantly higher computational resources than BEM. A two-dimensional CFD numerical wave tank, developed generating and absorbing waves with the waves2Foam toolbox (Jacobsen et al., 2012) of the open-source package OpenFOAM, is used for comparative purposes.

REFERENCES:

Delauré, Y. & Lewis, A. (2003). “3D hydrodynamic modelling of fixed oscillating water column wave power plant by a boundary element methods.” Ocean Engineering. 30. 309-330. 10.1016/S0029-8018(02)00032-X.

Bingham, H.B.; Ducasse, D.; Nielsen, K. et al (2015). “Hydrodynamic analysis of oscillating water column wave energy devices.” J. Ocean Eng. Mar. Energy 1, 405–419 (2015). https://doi.org/10.1007/s40722-015-0032-4

Faÿ F.-X. (2020). “Modelling and Control for the Oscillating Water Column in Wave Energy Conversion.” PhD Thesis, Universidad del País Vasco.

Jacobsen, N.G., Fuhrman, D.R. & Fredsøe, J., (2012). “A wave generation toolbox for the open-source CFD library : OpenFoam”. International Journal for numerical methods in fluids, 70, pp.1073–1088.

Simonetti, Irene & Cappietti, Lorenzo & Elsafti, Hisham & Oumeraci, Hocine. (2015). “Numerical Modelling of Fixed Oscillating Water Column Wave Energy Conversion Devices: Toward Geometry Hydraulic Optimization.” 10.1115/OMAE2015-42056.

Penalba, M., Kelly, T., Ringwood, J. 2017, NEMOH for Modelling Wave Energy Converters: A Comparative Study with WAMIT. 12th European Wave and Tidal Energy Conference , Cork, Ireland. https://www.researchgate.net/publication/319160625.
Dynamic Responses of a 1:5-Scale Ocean Current Energy Converter
Authors: Yang Shun-Han , Hung Yu-Chi , Yang Ray-Yeng , Hou Tien-En , Mu Ling-Ji , Huang Shen-Wei , Guo Jenhwa , Lin Shueei-Muh
Published: September 2023

The objective of this study is to numerically evaluate the dynamic responses of the Floating Kuroshio Turbine (FKT)—an ocean current energy converter—installed for field testing. In autumn 2022, the FKT was installed and tested at a 1:5 scale in the open sea area, located 1 kilometre off the LiuQiu Island coast, Taiwan. Because of unfavourable site conditions, the mooring and power cable systems for the FKT had to be customarily designed for the testing conditions. An investigation of the dynamic motions and structural responses of the mooring and cable systems was performed prior to physical testing to ensure the integrity of the testing campaign. The numerical analyses were performed using the commercial software DNV SIMA, where the prospect of the surfaced FKT and the mooring entanglement were evaluated and compared. This paper details the modelling process and the evaluation of the dynamics of the entire FKT system. Finally, the challenges and potential improvements for numerical assessments of a testing-oriented offshore marine energy system are identified and discussed.
Study on Wave Energy Conversion Problem of Turbine-Integrated OWC Chamber
Authors: Kim Jeong-Seok , Park Sewan , Kim Gilwon , Park Ji-Yong , Kim Kyong-Hwan , Nam Bo Woo , Cho Su-Gil , Shin Seung-Ho
Published: September 2023

An oscillating water column (OWC) device is a promising wave energy converter (WEC) to utilize ocean wave energy resources. The OWC chamber absorbs the kinetic energy of ocean waves and converts the water column motion to reciprocating airflow. A power take-off system (PTO-system) of the OWC-WEC consists of an air turbine, generator, and power control system. An airflow drives an air turbine, which rotates a generator to produce electricity. The air turbine induces a pressure fluctuation due to its aerodynamic characteristics, which directly affects the fluid motion inside the chamber. In this study, the wave energy conversion problem of the OWC-WEC was discussed based on the experimental and numerical simulation results, considering the turbine-chamber interaction. The wave energy conversion problem from wave to power was solved using the finite element method (FEM)-based numerical wave tank in the time domain. The air turbine was numerically modeled based on aerodynamic coefficients and inertia properties. The validity of the present numerical method was examined by comparing it with the experimental results conducted in a two-dimensional wave flume at the Korea Research Institute of Ships and Ocean Engineering (KRISO). The effect of the turbine-chamber interaction on the energy conversion performance was investigated regarding the various rotational speeds of the air turbine based on experimental and numerical analysis. It was observed that the rotational speed conditions of the turbine, where the hydrodynamic performance of the OWC chamber and the aerodynamic performance of the turbine could be maximized, were different from each other. Therefore, it can be seen that a control technology considering the combined performance of the chamber and air turbine is required to maximize the energy conversion performance of the OWC-WEC.
Internal waves
Authors: Raghukumar Kaustubha , Jones Craig , Chang Grace , Roberts Jesse
Published: September 2023

Internal waves are ubiquitous oceanographic features that occur in various forms across the world’s oceans. They manifest themselves as interface waves across ocean density layers that represent the interplay between buoyancy and gravitational forces, and are typically classified as linear and nonlinear internal waves. Nonlinear internal waves are characterized by isopycnal displacements that can exceed 30 m, and current velocities that approach 1 m/s. Internal wave energy converters, if developed, could have the advantage of no surface expression and provide for the availability of renewable ocean energy in regions of scant surface wave energy resources.

Here, internal wave energies were computed at two locations: the New Jersey continental shelf and the coast of Central California. The available energy resource calculated for internal waves was then compared against surface gravity wave resources at each of these locations. Results suggest that the internal wave energy flux is comparable to that of surface waves on the New Jersey continental shelf during the summer of 2006 but is two orders of magnitude lower than that of surface waves in Central California during the summer of 2017. When expressed in terms of forces on a cylindrical structure, internal wave forces are an order of magnitude lower than that of surface waves on identically sized cylinders. However, the forces of the two resources are comparable when the diameter of the cylinder is doubled for the internal wave calculations. This suggests that while a larger energy converter would be required to harness internal wave energy, the larger size could be a reasonable tradeoff for advantages such as the lack of surface expression and the availability of energy in regions of limited surface wave energy resources.

These results could potentially pave the way for longer-time scale characterization of internal waves and the development of devices to harness this energy resource (thereby powering the Blue Economy), while augmenting the portfolio of marine renewable energy resources. Further, the dominance of internal wave energy resources during summer seasons when the water column is stratified can augment the surface wave energy resource that can be diminished during the summer season.
Experimental evaluation of phase and velocity control for a cyclorotor wave energy converter
Authors: Ermakov Andrei , Thiebaut Florent , Ringwood John
Published: September 2023

The research presented in the paper is dedicated to the analysis of the 3D experimental testing results of a 1:20 scale prototype LiftWEC cyclorotor wave energy converter (WEC). The scaled prototype was built and tested in the Hydraulic and Offshore Engineering wave Tank (HOET) by Ecole Centrale Nantes (ECN) in 2022. The analysis is conducted using the analytical control-oriented point-vortex model. The presented research covers a range of tests, with particular focus on cases where positive mechanical power generation has been recorded. The analysis of such cases is important, in highlighting the conditions needed for optimum energy conversion, for future development of cyclorotor WEC technology. The study also reviews the results of tests where the rotor rotational speed is varied within each period of monochromatic waves. This is the first experimental test of such a control strategy for cyclorotor WECs.