bluuebunny/crossref_metadata_2025 huggingface dataset:
THE SOLVING OF PERSISTENCE PROBLEMS OF DRUGS ON THE BASIS OF IVERMEKTIN
Authors: Khalikov  , Marchenko  , Khalikov
Published: August 2019

Ivermectin-based preparations that have been intensively used in veterinary practice for more than 30 years have contributed to the development of resistance to drugs based on it, and this problem is very relevant in modern parasitology. One of the ways to solve this problem is the development of combined preparations based both on new ivermectin derivatives and the inclusion of preparations from other class-es of chemical compounds in their composition. We have proposed an alternative method, i.e. the mechanochemical modification of the substance ivermectin using water-soluble polymers. This paper presents the results of modifying the substance of ivermectin with arabinogalactan polysaccharide (AG), isolated from Siberian larch Larix sibirica by joint machining of components in a variable-voltage shred-der activator. During jointly machining ivermectin with samples of arabinogalactan from three alternative sources, compositions of "Ivermectin: AG" (1:10), which have increased solubility (more than 10 times as compared with the original substance of ivermectin), were obtained. The study of the parasiticidal efficacy of the obtained compositions of ivermectin in intestinal helminthiases was carried out on sheep. As a result of the experiments to evaluate the compositions of ivermectin with three samples of AG, it was found that their use of helminthic efficacy did not show the advantage of any of the batches of polysaccharide. To a greater extent, the effective-ness of the compositions of ivermectin was influenced by the dosage of the drug. Biological testing of the obtained compositions of ivermectin showed the possibility of reducing the dosage of ivermectin by 2 or more times while maintaining high ef-ficiency. The obtained data indicate the promising outlook for a mechanochemical approach for modifying the physicochemical and biological properties of prepara-tions based on ivermectin in solving problems of resistance.
HELMINTH FAUNA OF MUSTELIDS (NEOVISON VISON, LUTRA LUTRA, MARTES MARTES, MUSTELA PUTORIUS, MELES MELES) AT CENTER OF EUROPEAN PART OF RUSSIA (Preliminary results)
Authors: Tsvetkov  , Korablev
Published: August 2019

Helminthological autopsies of Mustelids from various districts of Pskov, Тver and Smolensk region were carried out. To determine the prevalence rates of the infestation, an extensive invasion index was used. According to the results of helminthological autopsies, a list of detected helminthes is given. For the first time on the study area, 14 species of helminthes were recorded in studied Mustelids. Two of the found species of helminthes parasitize in Mustelids in larval form. The maximum variety of species is observed among the Nematoda class. The data on the number of detected helminth species in Mustelids in certain districts of the Tver, Pskov and Smolensk regions, as well as indicators of the frequency of helminthes were given. The maximum number of helminth species is recorded in Mustelids in the Novosokolnichesky district of the Pskov region. Extensiveness of invasion of all studied species of Mustelids, excluding otter, is 100%. According to the indicators of extensiveness of invasion in the studied Mustelids, Isthmiophora melis, Capillaria mucronata, Capillaria putorii, Filaroides martis are prevalent. The maximum number of species of parasitic worms is recorded in pine marten. The research results indicate the dominant influence of the trophic factor in the formation of the helminth fauna of martens that inhabit the study areas.
PHYTOHORMONAL REGULATORY MECHANISM OF THE ONTOGENESIS OF HETERODERIDES’ ACTIVATION AND SYNCHRONIZATION
Authors: Babich  , Babich  , Statkevich
Published: August 2019

Studies using the developed device confirmed the attractive properties of the aquatic extracts of host plants, as well as the high trophic receptivity of the invasive larvae of cyst nematodes. The greatest stimulation of the release and active migration of larvae from cysts was observed when phytoncids were introduced by cultivated host plants at a distance of 2.5–5 cm from the object of study at an optimal humidity of 60–70% of the total soil moisture content. At the same time, the aqueous extracts of the roots of the initial phases of plant growth and development compared to the extracts of the subsequent organogenesis phases were the most attractive. We believe that the larvae react most to the increased content of phytohormones, cytokinins, because their synthesis in comparison with other growth activators mainly occurs in the root system of plants. Nematode isolation of enzymes in plant tissue causes a high content of phytohormones, which are catalysts for the formation of new young roots, thereby providing optimal conditions for the invasion and development of next-generation larvae. Certain stimulating effect was also shown by extracts from other plant organs, which indicates the integrity of the flow of all physiological processes in the plant organism. Due to the genetically fixed mechanism of activation and suspension of physiological processes, a clear synchronization of the ontogenesis of cyst nematodes in accordance with the organogenesis of host plants has been noted. Since the development of heteroderides occurs only in one plant populated by them, sedentary phytoparasites react sensitively to changes in the biochemical composition of the plant organism, due to biological aging or adverse factors of different nature, causing their pathology. The perennial cyclical nature of the development of sedimentary nematodes in accordance with the organogenesis of typical host plants caused the formation of their population adaptation.
THE HEMATOLOGIC STATUS OF CATTLE AT THE TREMATODOZNY INVASION
Authors: Shelyakin  , Semenov  , Stepanov
Published: August 2019

The work is devoted to the study of the activity of enzymes of the antioxidant defense system in the blood of cattle from infested trematodes performed. Investigations were carried out in one of the farms of the Voronezh region in 10 cows of Simmental breeds infested with trematodes, and 10 cows are clinically healthy. The authors found that the antioxidant activity of enzymes of blood cows at trematodosis invasion is characterized by the increasing of the content of ceruloplasmin and catalase activity, a decrease in the activity of peroxidases and superoxide dismutase. The use of initiation of an antiparasitic in combination with immunomodulators increases the activity of enzymes antioxidant protection of the blood system of cattle. Effective control of trematode imagopulation is achieved by administering anthelmintic drugs to host animals (de-worming). Treatment of animals with trematodes not only frees the host from the pathogen but also prevents further dispersion of helminth eggs in the external environment. Where there is a population of trematodes, prophylactic deworming is carried out twice a year. Thus, the control of the functional state of the enzyme antioxidant defense system has a diagnostic value over the state of the metabolic status of animals and is effective in treating trematodosal invasion.
MODULATORY EFFECT OF PROBIOTIC THERAPY ON INTESTINAL LYMPHOCYTES IN MICE INFECTED WITH TRICHINELLA SPIRALIS
Authors: Dvorožňáková Emília , Vargová Miroslava , Lauková Andrea , Revajová Viera
Published: August 2019

Important components of the intestinal mucosal immunity are free intraepithelial and lamina propria lymphocytes involved in the regulation and activity of the immune response. This study detected the presence of helper CD4 and cytotoxic CD8 T lymphocytes, and B lymphocytes in the small intestine of mice treated with probiotic strains and infected with Trichinella spiralis. Bacterial strains of different origin (Enterococcus faecium CCM8558, Enterococcus durans ED26E/7, Lactobacillus fermentum CCM7421, Lactobacillus plantarum 17L/1) were administered daily in dose of 109CFU/ml in 100 μl and mice were infected with 400 larvae of T. spiralison 7th day of treatment. L. fermentum CCM7421 and L. plantarum 17L/1 increased numbers of helper CD4 T cells in the epithelium and cytotoxic CD8 T cells in the lamina propria on 7th day of administration (before parasitic infection). T. spiralisinfection caused a significant inhibition of examined lymphocyte subpopulations from 5 to 25 days post infection (p.i.). Lactobacilli restored the CD4 T cell numbers in the epithelium and lamina propria on the level of healthy control from day 11 p.i. All strains stimulated the numbers of CD8 T cells in infected mice, but in comparison to control, CD8 T cells were reduced in the epithelium until day 25 p.i. and in the lamina propria only on day 5 p.i. An inhibition of B cells (CD19) in the small intestine after T. spiralis infection was not affected by probiotic therapy till day 25 p.i., but a stimulation of B cells was found after treatment with E. durans ED26E/7 and L. fermentum CCM7421on day 32 p.i. The obtained results confirmed the strain-specific immunomodulatory effect of probiotic bacteria. The greatest immunomodulatory potential on the gut CD4 and CD8 T lymphocytes during T. spiralis infection was confirmed by L. fermentum CCM7421 and L. plantarum 17L/1. Strains E. faecium CCM8558 and E. durans ED26E/7 activated only cytotoxic CD8 T cells in the lamina propria.
REGULATION OF THE DEVELOPMENT OF FUSARIOUS DRYING AND MELOYDOHYNOSIS ON THE MELON WITH THE CHITINOLYTIC MUSHROOM APHANOCLADIUM ALBUM MX-95
Authors: Gallo  , Sasanelli  , Ciccarese  , Migunova  , Toderas  , Konrat  , Rusu  , Iurcu-Straistaru
Published: August 2019

The use of biological agents is one of the promising strategies for the regulation of populations of pests that have the least impact on the environment. An experiment using the chitinolytic fungus Aphanocladium album MX-95 (AA MX-95) was carried out on melon plants in a greenhouse with a natural background infection of Fusarium oxysporum f. sp. melonis and the Southern Gall nematode Meloidogyne incognita in Valenzano (Province of Bari, Apulia). A suspension of MX-95 isolate (2 x 107 CFU / mL) was added at a concentration of 2.5 l / plot using plastic tubes fitted with water emitters (according to each melon plant in the row). The suspension of the fungus was added 2 weeks before planting and after planting 3 times every 2 weeks. There was also an option with processing only after landing (3 treatments). Control options included untreated soil and a soil with a diazomet (600 kg / ha), distributed 30 days before planting. Versions with AA MX-95 significantly reduced fusarial wilt, especially when the treatment was before and after planting, much more effective than with chemical control of the diazomet (fungicide and nematicide). The effect of the fungus, introduced before and after planting, was especially manifested in the development of meloydohynosis. The index of galling and the population number of nematodes at the end of the experiment in the soil were reduced by 50 and 63%, respectively, compared with the control. The effectiveness of the AA MX-95 applied before and 3 times after planting was similar and did not differ from the chemical standard diazomet.
Assessing the long-term face memory of highly superior and typical-ability short-term face recognisers
Authors: Davis Josh P , Bretfelean Diandra , Belanova Elena , Thompson Trevor
Published: August 2019

Outstanding long-term unfamiliar face recognition ability is the hallmark of the exceptionally skilled ‘super-recognisers’. Indeed, international police super-recogniser units rely on members identifying unfamiliar suspects from CCTV after substantial delays. Yet, virtually all research has employed brief retention intervals to evaluate super-recognisers’ capabilities. To address this gap in the literature, in Experiment 1, participants (n = 597), including 84 super-recognisers, viewed 10 60s target-actor videos and identified targets from 10 target-present line-ups after random delays of 1, 7, 14, 28, or 56 days. In Experiment 2, participants (n = 1421), including 206 super-recognisers, viewed 20 30s target-actor videos and identified targets from 10 target-present and 10 target-absent line-ups after delays of virtually none, 1, 7, and 28 days. Correct target-present identifications, and with smaller effect sizes, correct target-absent line-up rejections were predicted by short-term face memory and matching test scores, and decision confidence. Delay also predicted correct target-present identifications but not correct rejections. With higher confidence, most super-recognisers (82.5%) individually exceeded overall control mean hit rate accuracy. However, only a minority of comparisons were significant (28.5%). The important applied implication was the demonstration that not all super-recognisers can sustain their skills over longer retention intervals. Therefore, recruitment to super-recogniser research groups, or roles in policing or security require longer-term face memory tests. Important theoretically was the finding that super-recogniser’s estimated forgetting curve was shallower than that of controls, implying that their enhanced mnemonic system for faces allows representations in memory to be more reliably sustained for far longer.
The Early Modern Lyric: A Literary Wilderness of World Literature
Authors: Porter David A.
Published: August 2019

This article explores several aspects of the early modern poetic tradition as an antidote to presentism in comparative and world literature studies. A passage from Giovanni Battista Pigna’s Renaissance synthesis of Aristotelian and Horatian poetics is used to comment on comparative readings in general. This is followed by close readings of two dream poems by the early modern Italian Giovanni Aurelio Augurello and the modernist Spanish poet Antonio Machado, both of which relate to Renaissance literary traditions in different ways. Two different agonistic poems, one by Pierre-Daniel Huet and one attributed to a Frisian folk hero, are also subject to analysis in order to explore how the process of historical selection reshapes the literary corpus and subjugates certain types of writing to neglect.
Poetry in English as Comparative and World Literature
Authors: Hart Jonathan Locke
Published: August 2019

English literature as a national literature is in many ways a non-starter. Form and context, language and translation all exert centrifugal forces on English language and literature and, more specifically, poetry. English poetry becomes poetry in English, but even from the start in Old English, there are external cultural and linguistic forces. Here, I do not deny that we speak of English poetry or poetry in English, but I wish to explore the countervailing pressures away from the literature of a nation or an unbroken poetic tradition in English because literature in English was written before England was unified and is written in English in English-speaking places and other territories that have changed over time. T.S. Eliot’s tradition and the individual talent, which he first discussed in The Egoist in 1919, is a perceptive idea, but I would suggest that some of the individuals, even early on, were bilingual or multilingual and that the tradition is not unified culturally, socially, and politically. So here I offer a brief selection of literary history – that is, a historical account of poetry in English, in the context of Latin and other languages, with examples from Anglo-Saxon texts through those of Shakespeare and Ezra Pound to those works in the present – that shows aspects of comparative and world poetry from the beginning and not simply English poetry or poetry in English.
Global Rhythms: Setting the Stage for World Poetry in 1960s London
Authors: Edmond Jacob
Published: August 2019

This article locates the origins of contemporary understandings of world poetry in a set of institutions and poetic practices that developed in the 1960s, as evinced by a series of performances in London at that time, including the 1965 International Poetry Incarnation, organized by Allen Ginsberg; Andrei Voznesensky’s near-simultaneous performance at the Theatre Royal Stratford; Kamau Brathwaite’s 1967 performance of Rights of Passage at the Jeanetta Cochrane Theatre; and a 1969 bilingual performance of Aimé Césaire’s Cahier d’un retour au pays natal, directed by John La Rose. The concerns of the Caribbean Artists Movement, which sponsored the latter two performances, seem far from the Cold War and counterculture context of the International Poetry Incarnation. Yet both took inspiration from the theatrical performances of Russian poets like Voznesensky. Such surprising interconnections reflect a newly self-conscious poetic internationalism, for which Voznesensky, Ginsberg, Brathwaite, and La Rose all sought a formal embodiment in the global rhythms of the performed and tape-recorded word.
Chrysis serena Radoszkowski, 1891, a new synonym of Ch. zonata Dahlbom, 1854 (Hymenoptera, Chrysididae)
Authors: Rosa P.
Published: August 2019

Chrysis serena Radoszkowski, 1891 is synonymised with Ch. zonata Dahlbom, 1854. The new synonymy is discussed and the updated distribution of Ch. zonata in Russia is given.
A new species of Hedychridium Abeille de Perrin, 1878 from Kazakhstan (Hymenoptera: Chrysididae)
Authors: Rosa P.
Published: August 2019

A new species, Hedychridium alatum sp. nov., from South East Kazakhstan is described. The previously named H. sericifrons species group is here renamed in H. flos species group. Cases of body discoloration in desert-dwelling species are reported.
Improve Performance of Wing Plan by Gettingnd of the Boundary Layer Control Using Electric System
Authors: Saeed Nazhat , Ahmed Yasser , T.dawod Basmah.
Published: August 2019

The amount of drag produced significantly depends on shape of the airfoil. These implementation concerns the lift and drag analysis of three different profiles of airfoils, which are symmetrical aerofoil (NACA 0015, NACA0012) and cambered aerofoil (NACA 4415) have different volume. NACA0015 is provided with perforated tube fixed at 75% from the leading edge for suction. Electrical control system used to control the suction operation the three different types of objected has been tested at a sub-sonic wind tunnel and experimental data has been obtained at different Reynolds’s number and angle of attack. The three airfoils (symmetrical NACA 0015, NACA0012 and cambered with NACA 4415) tested at (00, 50, 100, 150 and 180) angles of attack. All the three objects tested at Re (1.72, 2.9,4, 5.2 and 6.3 x105). The cambered airfoil has been given least drag among than all the airfoils.  The drag force  of  all test model are decreased when  the value of Reynolds number are increased and NACA 4415 exhibit less drag and high lift in comparison with other models that used in this study. Suction technique is more active at lower values of Re –number.
Elemental Imagination and Film Experience
Authors: de Roo Ludo
Published: August 2019

In an age of ecological disasters and increasing environmental crisis, the experience of any cinematic fiction has an intrinsic ethical potential to reorient the spectator’s awareness of the ecological environment. The main argument is that the spectator’s sensory-affective and emphatically involving experience of cinema is essentially rooted in what I call “elemental imagination.” This is to say, first, that the spectator becomes phenomenologically immersed with the projected filmworld by a cinematic expression of the elemental world, and second, much like there is no filmworld without landscapes, the foundational aspect of elements are revealed as preceding and sustaining the narrative and symbolic layers of film experience. While suggesting the existential-ethical potential of this fundamental process of film experience, the second aim of this article is to show that this form of elemental imagination complements more mainstream “environmentalist” films, such as climate change documentaries and blockbuster apocalyptic genre films.
URGENSI PENGGUNAAN MULTIMEDIA INTERAKTIF TERHADAP PENINGKATAN MOTIVASI BELAJAR SISWA DALAM PEMBELAJARAN BAHASA ARAB KELAS VA MIN MALANG 2
Authors: Mappanyompa Mappanyompa Mappanyompa , Mustapa Ali Mustapa Ali Mustapa Ali
Published: August 2019

Proses pembelajaran adalah suatu rangkaian kegiatan yang sangat kompleks, tidak hanya bertujuan untuk mentransfer pengetahuan kepada siswa, akan tetapi sebelum itu guru harus menyiapkan banyak hal dan salah satunya adalah membuat siswa termotivasi, senang dan butuh terhadap pelajaran tersebut sehingga proses pembelajaran berjalan sesuai harapan. Terutama pada pelajaran bahasa Arab yang cukup sulit untuk siswa tingkat Madrasah Ibtidaiyah (MI). Oleh sebab itu perlu adanya kondisi belajar yang menyenangkan yang membuat siswa termotivasi, salah satunya adalah dengan membuat media (multimedia interaktif) sehingga materi tidak terasa begitu sulit.
Curcumin Downregulates GSK3 and Cdk5 in Scopolamine-Induced Alzheimer’s Disease Rats Abrogating Aβ40/42 and Tau Hyperphosphorylation
Authors: Das Tushar Kanti , Jana Piyali , Chakrabarti Swarup Kumar , Abdul Hamid Mas R.W.
Published: August 2019

Alzheimer’s disease (AD) is the most common form of dementia. Extracellular amyloid-β (Aβ) aggregation and tau hyperphosphorylation are the key drivers of AD. Glycogen synthase kinase 3 (GSK3) and cyclin dependent kinase 5 (Cdk5) have been known as leading applicants arbitrating abnormal tau hyperphosphorylation. Thus, we evaluated the efficacy and underlying mechanism of action of curcumin in scopolamine-induced AD rats in our study. We found that curcumin-treated AD rats markedly reduced the levels of Aβ40 and Aβ42 in the brain and in the plasma in comparison to untreated AD rats. Moreover, the levels of phosphorylated tau at Ser396 (PHF13), Ser202/Thr205 (AT8), and Aβ40/42 (MOAB2) were decreased significantly in AD rats treated with curcumin. Phospho-GSK3β (Tyr216), the active form of GSK3β, and total GSK3β were significantly decreased in AD rats treated with curcumin. Furthermore, Cdk5 and its activators p35 and p25 were significantly decreased in curcumin-treated AD rats. The reduced levels of Cdk5, p35, p25, and GSK3β in curcumin-treated AD rats may result decreased Aβ aggregation and tau hyperphosphorylation, thus ameliorating AD. Impaired spatial memory and locomotor activity in AD rats were partially reversed by curcumin. Therefore, curcumin, as a natural compound present in turmeric, may be a more effective therapeutic agent in the treatment of AD in humans.
Look before you leap: Barriers to big data use in municipalities
Authors: Moody Rebecca , Plat Victor , Bekkers Victor
Published: August 2019

In this article we confront existing literature on barriers in big data implementation for policy making in municipal governments. We have conducted four cases in a Dutch municipality in which big data is implemented for policy solutions. This has led us to develop a new, comprehensive model which explains which barriers exist while making implementing big data. Dimensions such as the technological, the legal, the informational, the organizational, the ethical and the government-citizen relation dimension will be included in the study. It will be argued that ‘hard’ barriers, such as technological and legal prove to be of far lesser influence than literature suggests. On the other hand, the ‘soft’ barriers such as alignment issues and ethical considerations going further than legal aspects prove to be far more determining barriers for the policy making process in implementing big data solutions in municipal governments.
A Review of Papillary Renal Cell Carcinoma and MET Inhibitors
Authors: Rhoades Smith Katherine Emilie , Bilen Mehmet Asim
Published: August 2019

Papillary renal cell carcinoma (PRCC) is a subtype of renal cell carcinoma (RCC) accounting for approximately 15–20% of cases and further divided into Type 1 and Type 2. Type 1 PRCC tends to have more alterations in the MET tyrosine kinase receptor than Type 2 PRCC. Treatment for RCC patients is based on studies with minimal participation from patients with PRCC; consequently, conventional therapies tend to be less effective for RCC patients with a subtype other than ccRCC (non-ccRCC). Since MET is a known alteration in PRCC, it is potential target for directed therapy. There have been many attempts to develop MET inhibitors for use in solid tumors including PRCC. The following review will discuss the current research regarding MET-targeted therapy, MET inhibitors in clinical trials, and future directions for MET inhibitors in PRCC.
Correlation between CT based radiomics features and gene expression data in non-small cell lung cancer
Authors: Wang Ting , Gong Jing , Duan Hui-Hong , Wang Li-Jia , Ye Xiao-Dan , Nie Sheng-Dong
Published: August 2019

OBJECTIVE:

Radiogenomics investigates radiographic imaging phenotypes associated with gene expression patterns. This study aims to explore relationships between CT imaging radiomics features and gene expression data in non-small cell lung cancer (NSCLC).

METHODS:

Eighty-nine NSCLC patients are included in the study. Radiomics features are extracted and selected to quantify the phenotype of tumors on CT-scans. Co-expressed genes are also clustered and the first principal component of the cluster is represented, which is defined as a metagene. Then, statistical analysis was performed to assess association of CT radiomics features with metagenes. In addition, predictive models are built and metagene enrichment are conducted to further evaluate performance of NSCLC radiogenomics statistically and biologically.

RESULTS:

There are 187 significant pairwise correlations between a CT radiomics feature and a metagene of NSCLC, where eighteen metagenes are annotated with Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) terms. Metagenes are predicted in terms of radiomics features with an accuracy of 41.89% –89.93%.

CONCLUSIONS:

This study reveals the associations between CT imaging radiomics features and NSCLC co-expressed gene sets. The findings suggest that CT radiomics features can reflect important biological information of NSCLC patients, which may have a significant clinical impact as CT is routinely used in clinical practice, assisting in improving medical decision-support at low cost.
KEWEWENANGAN PENGADILAN DI DALAM MEMERIKSA DAN MENGADILI SENGKETA PERBANKAN SYARIAH
Authors: Braviaji Ervianto
Published: August 2019

ABSTRAKEksistensi Perbankan Syariah adalah usaha perbankan yang menjalankan seluruh aspek operasional secara kelembagaan berdasarkan prinsip-prinsip syariah. Khusus terkait dengan kewenangan mengadili, Undang-Undang Nomor 21 Tahun 2008 tentang Perbankan Syariah tersebut pada Pasal 55 menyebutkan bahwa apabila terjadi sengketa Perbankan Syariah, maka yang berwenang adalah Pengadilan Agama kecuali ditentukan lain dalam akad. Metode penelitian secara yuridis normatif berbasis data sekunder. Hasil penelitian menunjukan pertama, terjadinya dispute authority karena adanya choice of forum secara normatif dalam penyelesaian sengketa, Kedua, penerapan dalam putusan pengadilan terhadap sengketa perbankan syariah belum sesuai dengan kaidah-kaidah hukum. Kata Kunci : Kewenangan, Pengadilan, Perbankan Syariah.
PERLINDUNGAN HUKUM TERHADAP KARYAWAN YANG MENGALAMI PEMUTUSAN HUBUNGAN KERJA SETELAH PUTUSAN PENGADILAN BERKEKUATAN HUKUM TETAP
Authors: Hadi Abdul
Published: August 2019

ABSTRAK Jaminan kepastian hukum yang diberikan Pasal 170 Undang-Undang No. 13 Tahun 2003 tentang ketenagakerjaan seakan belum mampu menjawab perlindungan hukum terhadap pekerja. Mekanisme penyelesaian perselisihan hubungan industrial yang diatur Undang-Undang Nomor 2 Tahun 2004 seakan menjadi kontradiktif ketika putusan batal demi hukum dengan kewajiban pengusaha untuk mempekerjakan kembali pekerja yang telah dilakukan PHK sepihak banyak tidak dilaksanakan pengusaha termasuk putusan yang dikeluarkan oleh pengadilan sekalipun. Putusan melakukan perbuatan hukum di dalam kasus PHK sepihak seperti mempekerjakan kembali dan apabila pengusaha tidak dengan sukarela melaksanakan amar putusan untuk mempekerjakan kembali pekerja sulit untuk dilakukan eksekusi. Ini menjadi salah satu kelemahan dalam Pengadilan Hubungan Industrial selama ini di dalam menjamin perlindungan hukum terhadap pekerja.Kata Kunci : Perlindungan Hukum; Karyawan; Pemutusan Hubungan Kerja
PEMAKZULAN TERHADAP PRESIDEN DAN ATAU WAKIL PRESIDEN DITINJAU DARI UNDANG UNDANG DASAR NEGARA REPUBLIK INDONESIA TAHUN 1945
Authors: Prayitno Herman Bastiaji
Published: August 2019

ABSTRAK Batas minimum kuorum dan persetujuan anggota DPR itu tidak sejalan dengan konstitusi, meskipun Undang-Undang Dasar 1945 memang tidak menetapkan batas minimalnya. Soalnya, ada pasal pada UUD 1945 yang memberikan kewenangan kepada DPR untuk mengusulkan pemakzulan presiden dan wakil presiden kepada Mahkamah Konstitusi, yang prosesnya pasti bermula dari penggunaan hak tersebut. Usulan pemakzulan itu, menurut Pasal 7-B ayat 3 UUD 1945, harus didukung sekurangnya dua pertiga anggota DPR yang hadir dalam rapat paripurna dan diikuti oleh sekurangkurangnya dua pertiga anggota DPR. Maka sudah seharusnya batas minimal kuorum dan persetujuan DPR untuk memakai hak menyatakan pendapat dalam UU Nomor 27 tidak lebih berat dari syarat pemakzulan yang ditetapkan UUD 1945. Kata Kunci : Pemakzulan; Presiden; Undang-undang Dasar 1945
Análise do esforço fiscal na arrecadação do IPTU para os municípios do estado do Ceará utilizando modelo de fronteira estocástica
Authors: Sobrinho Antônio Leal , Alencar Frederico Augusto Gomes de
Published: August 2019

Baseado no entendimento da baixa exploração do Imposto Predial e Territorial Urbano (IPTU), este artigo tem como objetivo calcular o índice de esforço fiscal (IEF) para os municípios do estado do Ceará durante os anos de 2008 e 2016 no tocante à arrecadação do IPTU. A partir de um exercício de estimação das diferentes capacidades de arrecadação, e por meio do aproveitamento das características próprias de cada esfera governamental, pretende-se relacionar suas capacidades efetiva e potencial na obtenção dessas receitas, com a criação de um ranking ordenando e classificando os municípios. A análise se deu por meio de um modelo econométrico de fronteira estocástica, que expressa a quantidade máxima de produto que pode ser obtido a partir de uma dada quantidade de insumos. O estudo comprova que os municípios se mostram, em sua maior parte, ineficientes, e que mecanismos de melhoria na arrecadação do IPTU precisam ser bastante aprimorados.
O termo de ajustamento de gestão e o controle externo: a novel experiência no âmbito do tribunal de contas do estado do Paraná
Authors: Zelinski Renata Brindaroli
Published: August 2019

O tema do artigo é o Termo de Ajustamento de Gestão (TAG) e a sua relação com o controle externo e, notadamente, a sua aplicação pelo Tribunal de Contas do Estado do Paraná (TCE/PR). Os objetivos do trabalho são expor a natureza jurídica do TAG inserido no âmbito da administração pública contemporânea, que preza pela consensualidade, bem como a sua conformidade com o controle externo a cargo das Cortes de Contas, especificamente a paranaense, a qual prevê na sua Lei Orgânica a possibilidade de se firmar o Termo de Ajustamento de Gestão visando a adequação dos atos e procedimentos dos órgãos ou entidades sujeitos ao seu controle, cuja regulamentação se deu com o advento da Resolução nº 59/2017, do TCE/PR. Como método, o artigo utiliza a pesquisa bibliográfica, legislativa e jurisprudencial, buscando evidenciar a viabilidade de atuação do controle externo a partir da concepção da administração pública consensual, comprovando que o TAG pode ser levado a efeito no âmbito da jurisdição afeita à Corte de Contas, na medida em que se revela adequado, proporcional e concreto para os fins colimados no texto constitucional e na legislação em vigor, inclusive servindo como instrumento para promoção de políticas públicas que visam concretizar direitos fundamentais. Firmado o TAG e havendo a recomposição do dano, bem como a regularização dos gastos de recursos públicos e de questões formais de forma conciliatória, desnecessária se faz a atuação punitiva do Tribunal de Contas.
Sarcoma Radioinduzido Pós-Tratamento de Glioblastoma: Relato de Caso
Authors: Domingos Lisita Rosa Victor , Souza dos Anjos Caroline , Barile Marchi Candido Priscila , Soares Dias Junior Antonio , Airton Sordi dos Santos Evandro , Cavalcante Godoy Antonio Carlos , P. Saggioro Fabiano , Carlotti Junior Carlos Gilberto , Francisco de Oliveira Harley , Maris Peria Fernanda
Published: August 2019

Introdução: O glioblastoma multiforme é a neoplasia de sistema nervoso central mais letal, com sobrevida media em torno de 13 meses e a de pior prognostico dentre todos os gliomas. A abordagem terapêutica do glioblastoma consiste em neurocirurgia com ressecção máxima possivel do volume tumoral, seguida de radioterapia e quimioterapia. A radioterapia reduz o risco de recidiva tumoral por meio de lesao direta e indireta ao acido desoxirribonucleico tumoral. Os efeitos em longo prazo da radioterapia incluem necrose tecidual, vasculopatia e neoplasia induzida pela radiação. Os tumores malignos intracranianos secundários mais reportados incluem meningiomas, gliomas e sarcomas. O período de latência entre a radioterapia de cranio e o surgimento de lesões radioinduzida varia na literatura entre seis meses a 47 anos, com media de 18,7 anos. Relato de caso: O presente relato descreve o surgimento de sarcoma fusocelular de alto grau radioinduzido apos dez meses em paciente que recebeu tratamento de glioblastoma no Hospital das Clinicas de Ribeirao Preto da Universidade de São Paulo. Conclusão: A raridade dessa associacao se deve provavelmente a baixa sobrevida dos pacientes com glioblastoma, limitando assim o tempo para desenvolvimento de neoplasias secundarias.
بناء المحفظة المثلى للاسهم بأستعمال الخوارزمية الوراثية متعددة الاهداف – بحث تحليلي مقارن في سوق العراق للاوراق المالية
Authors: اسماعيل مصطفى منير , غناوي حيدر عدنان
Published: August 2019

تحدد الهدف الرئيس من البحث في بناء محفظة أستثمار مثلى من الاسهم المدرجة في سوق العراق للاوراق المالية بعد توظيف الخوارزمية الوراثية متعددة الاهداف في ذلك خلال المدة الزمنية المحصورة بين (1/1/2006) لغاية (1/6/2018) في ضوء أسعار الاغلاق الشهرية للشركات المدروسة عينة البحث و البالغ عددها (43) شركة بعد اكتمال بياناتها و تلبيتها لشروط المعاينة اذ عززت مراجعة الادبيات تشخيص فجوة المعرفة و تحديد مكامن القصور على مستوى التجريب ، فكانت وجهة البحث الحالي تجسيداً للجوانب غير المشاهدة وغير المعالجة من قبل الباحثين الاخرين وبالاخص البيانات المفقودة و عدم عكس اسعار الاسهم لواقع التداول على مستوى الشركات و السوق المالي و اختتمت بتوظيف اداة الخوارزمية الوراثية متعددة الاهداف ، وبهذا فانها اما أقتصرت على بناء المحافظ و اختيار المثلى منها ، او توليد محافظ مثلى دون ايلاء الاهتمام لمسألة معالجة البيانات المفقودة في سلسلة البيانات ، او اغفال امكانية توليد محافظ استثمارية و تصنيفها كمثلى تبعا لتفضيلات المستثمر ، واخريات وظفت الخوارزمية الوراثية دون ربطها بهدفي المحفظة من عائد و مخاطرة ، وبعد تطبيق فكرة البحث بأداته المذكورة خلصت نتائج التحليل الكمي الى بناء محافظتين هي المحفظة المثلى في ظل البيانات الاصلية والمحفظة المثلى في ظل البيانات الاصلية المحسن ادائها بأستعمال الخوارزمية الوراثية متعددة الاهداف ، حققت المحفظة المثلى المحسن ادائها بأستعمال الخوارزمية الوراثية متعددة الاهداف أعلى مستوى للأداء لدرجة تفوقها على محفظة مؤشر سوق العراق للاوراق المالية و بما يؤشر صلاحية المزاوجة بين البرمجة الهدفية والخوارزمية الوراثية في بناء محفظة استثمار مثلى عالية الاداء تضمن للمستثمر في سوق العراق للاوراق المالية تحقيق المبادلة الصحيحة بين العائد و المخاطرة و بالشكل الذي ينعكس ايجاباً على تحقيق هدف تعظيم ثروته من موارده المحدودة .
علاقة استراتيجية التدريب بتعزيز النمو الذاتي للفرد
Authors: علي محمد حسين , لعيبي لمياء رحيم
Published: August 2019

الهدف الرئيسي لهذا البحث هو قياس تأثير استراتيجية التدريب في تعزيز النمو الذاتي للفرد ، أذ تشكل استراتيجية التدريب التوجه المعاصر لتنفيذ معظم الانشطة و المهام التي تقوم بها منظمات الاعمال للمزايا العديدة التي تتمتع بها , كما يمثل النمو الذاتي للفرد احدى المؤشرات التي يمكن الاستناد عليها لتحديد قدرة المنظمة على تحقيق اهدافها , فقد اشارت مشكلة البحث الى قلة الوعي بأهمية الدور التي تلعبه استراتيجية التدريب في تعزيز النمو الذاتي للفرد ومن اجل تحقيق البحث ومعالجة مشكلته فقد اعتمدت الباحثة على المنهج التحليلي, اذ اعتمدت الاستبانة كأداة رئيسية لجمع بيانات البحث و التي تم اعدادها بالاستناد الى عدد من المقاييس الجاهزة بعد ان تم اخضاعها لاختبارات الصدق و الثبات لتتلاءم مع اهداف البحث و التي تضمنت (42) فقرة وقد تم توزيعها على عينة قوامها (100) فرد عامل في وزارة الصناعة و المعادن قسم الصناعات الحربية و قد تم اختبارهم بطريقة العينة العشوائية البسيطة و قد اعتمدت الباحثة على البرنامج الاحصائي (  SPSS  ) في ادخال و تحليل البيانات و تحليل علاقات الارتباط و التأثير بين متغيرات البحث وقد افرزت الادوات الاحصائية المستخدمة في هذا المجال عدد من الاستنتاجات ابرزها ان استراتيجية التدريب تمارس دور مهم و معنوي من الناحية الاحصائية في تعزيز النمو الذاتي, و عليه اوصى الباحث بضرورة قيام المنظمة بتعزيز النمو الذاتي للفرد من اجل تمكينها من استعمال تطبيقات استراتيجية التدريب و تنفيذ الانشطة والمهام الموكلة اليها و التي بدورها سوف تسهم في تعزيز النمو الذاتي للفرد اتجاه المنظمة .
ANALISIS JENDER WACANA MATERI PELAJARAN BUKU TEKS BAHASA INDONESIA DI SD KELAS TINGGI BENGKULU SELATAN
Authors: S Eva
Published: August 2019

The research purpose to express stereotype women form and stereotype man form which constituante from jender, and equivalent jender form in text book Indonesian SD (elementary school). The text book selection as detailed examination object is text book Indonesian elementary school are purpose in elementary school high class South Bengkulu erlangga edition study 2010-2011 years. Speaking in text book are thorough beginning from four, five and six class. The research used analysis contents program. Analysis data involue the use of analysis data used. Analysis contents technic. Based on draft analysis sentence the thing which contains stereotype woman (SW), stereotype man (SP) and equivalent jender (KJ) interior discourse in text book it is sentence which give code apart. Equivalent form jender in the sentence in discourse text book Indonesia Language at elementary school high class Bengkulu South explain about equivalent character between woman and man in domestic zone and public which is not yet many get in four, five and six class, until book mentionet not yet equivalent jender. Based on result research can suggestion which is relation with necessarry text book which is give insight equivalent jender. In addition to needed sees jender in arranging curriculum Indonesia Language elementary school.
PENINGKATAN KEMAMPUAN MEMAHAMI TEKS ANEKDOT DENGAN METODE PEMBELAJARAN PENEMUAN SISWA KELAS X MIPA 2 SMAN 3 KOTA BENGKULU
Authors: Kencana Lia
Published: August 2019

The purpose of study was to determine the ability in comprehending anecdote text through discovery learning method. The subject of this research is the students grade X MIPA 2 SMAN 3 Bengkulu city academic tear 2015/2016. Kind of the research is classroom action research. The data of this research is the ability in comprehending anecdote text and students and teacher’s abservation sheet. Based on the research that discovery learning can increase ability in comprehending anecdote text for the students grade X MIPA 2 SMAN 3 Bengkulu City. The result can be seen in score action research cycle I with the average score 70,42 it is good category and in action research cycle II 80,85 it is the best category. The classical learning achievement in cycle I 48,39% and in cycle II 87,05%, it means that there is significant increase between cycle I and cycle II.
MECNÛN’DAN MELAMİ’YE KRİZİN OLAĞANLAŞMASI
Authors: GÜNAY-ERKOL Çimen
Published: August 2019

Osmanlı klasik şiiri, karmaşık Osmanlı
kültür ve folklorünü yansıtan kırık bir aynadır. Osmanlı lirik şiirini okurken
despotizmi şiirdeki her kapıyı açan anahtar olarak kabul eden yaklaşımlara
eleştirel yaklaşan Walter Andrews, şiiri “âşık-mâşuk”, “merkez-çevre” gibi
ikili karşıtlıklara indirgemek yerine, kimlikleri etkileyen etkileşimi ön plana
alarak farklı bir açıdan bakmayı önerir. Andrews, Gilles Deleuze ve Felix
Guattari’nin kuramsal eleştirileri ışığında incelediği şiirlerde “oluş”
halindeki kimliklerden söz eder ve “Mecnûn” ve “Melâmi” olarak adlandırdığı iki
fonksiyon tespit eder. Bu makalede, Andrews’un çalışmasından ilhamla, biri
despotik tahakküm ilişkilerinin diğeri ise Sufî
folklorünün ürünü olan bu iki “oluş hali” arasındaki etkileşim, Tanzimat’tan
itibaren giderek Divan şiirinin yerini alan romanlardaki karakterler
çerçevesinde ele alınmaktadır. Kimliğin bir inşa olduğuna ilişkin göndermeler
içeren ve kimliğin modernleşme ile ilgili bir sorunsal olarak ele alındığı
romanlar incelendiğinde, Sufizm kültürünün ve folklorunun etkisini yitirmesi ile
gözden kaybolduğu düşünülen Melâmi fonksiyonunun ortadan kalkmadığı, tıpkı
tarihsel olarak farklı tahakküm ilişkileri içerisinden yeniden üretilen Mecnûn fonksiyonu
gibi, Melâmi fonksiyonun da dönüşerek sürdüğü, Mecnûn fonksiyonunu etkilediği
ve dönüştürdüğü ortaya çıkmaktadır. Yazının ilk bölümünde Tanzimat
romanlarından Felâtun Bey ve Râkım Efendi (1875) ile İntibah
(1876) ve Servet-i Fünûn’a geçiş döneminin önemli romanlarından Araba
Sevdası (1896) ile bu dönemin doruğu kabul edilen Aşk-ı Memnu (1900) ve yazının ikinci bölümünde,
Milli Edebiyat romanlarından Ateşten Gömlek (1922) ve Yaban (1932) ele alınacak ve son olarak
Osmanlı-Türk modernleşmesine ilişkin konularda öne çıkan hikâyelere sahip olduklarından Fatih-Harbiye (1931) ve Huzur
(1949) incelenecektir.
Perceptions of team-based learning using the Team-Based Learning Student Assessment Instrument: an exploratory analysis amongst pharmacy and biomedical students in the United Kingdom
Authors: Parthasarathy Prabha , Apampa Bugewa , Manfrin Andrea
Published: August 2019

Purpose: This study aimed to evaluate students’ perception of team-based learning (TBL) amongst a cohort exposed to this methodology for the first time at a university in the United Kingdom.Methods: Between November and December 2018, 26 first-year Master of Pharmacy and 90 second-year Biomedical Science students of the School of Life Sciences, University of Sussex, United Kingdom were invited to participate and requested to complete a questionnaire that contained quantitative and qualitative questions. The quantitative component was based on the Team-Based Learning Student Assessment Instrument (TBL-SAI). It additionally contained questions about key student characteristics.Results: The response rate was 60% (70 of 116); of the participants, 74% (n=52) were females and 26% (n=18) males. The percentage of agreement in the TBL-SAI suggested a favourable response to TBL. The overall mean score for the TBL-SAI was 115.6 (standard deviation, 5.6; maximum score, 140), which was above the threshold of 102, thus suggesting a preference for TBL. Statistically significant differences were not found according to demographic characteristics. Students who predicted a final grade of ≥70% strongly agreed that TBL helped improve their grades. Some students highlighted issues with working in teams, and only 56% of students agreed that they could learn better in a team setting.Conclusion: This study shows that students exposed to TBL for the first time favoured several aspects of TBL. However, more focused strategies including team-building activities and expert facilitation skills could potentially tackle resistance to working in teams.
Noise Exposure and Hearing Impairment in Air Force Pilots
Authors: Muhr Per , Johnson Ann-Christin , Selander Jenny , Svensson Eva , Rosenhall Ulf
Published: August 2019

OBJECTIVE: The goal of this study was to estimate noise exposure and hearing impairments in Swedish military pilots. It also aimed to analyze possible relations between noise exposure and hearing impairments.METHODS: The study group was an open cohort of 337 male pilots.
They were longitudinally followed with pure tone audiograms every fifth year from the beginning of flight service until discharge. Outcome measures were prevalence of thresholds >20 dB HL and >40 dB HL at different ages, and incidence of impairments >20 dB HL, 30 dB HL, and 40 dB
HL. Exposure variables were individual flight data and noise dose measurements. The ISO 1999 Database A was used for reference data.RESULTS: At 50 yr of age, 41% of the pilots were exposed to an equivalent noise dose exceeding the EU action level of Leq 80 dB(A). We observed significant
elevated prevalence values of thresholds >20 dB HL in all age classes compared to the ISO 1999 Database A. These elevations were most pronounced at ages 30 and 40 yr and at 4 and 6 kHz in the left ear. Significantly elevated prevalence values of thresholds >40 dB HL compared to the ISO
1999 Database A were observed at age 40 and 50 yr at 4 and 6 kHz. In a Cox analysis we observed elevated hazard ratios of deteriorating thresholds with longer flight time/year in fast jet pilots.DISCUSSION: Military pilots had elevated prevalence values of hearing impairment. Of
the subjects, 41% had been exposed to noise exceeding the EU risk limit. Increased flight time/year and flying fast jets were associated with elevated risk of hearing deterioration.Muhr P, Johnson A-C, Selander J, Svensson E, Rosenhall U. Noise exposure and hearing impairment in
air force pilots. Aerosp Med Hum Perform. 2019; 90(9):757–763.
SINKRONISASI PENGATURAN PELIMPAHAN WEWENANG TINDAKAN MEDIS KEPADA PERAWAT UNTUK PELAYANAN KESEHATAN DI RUMAH SAKIT
Authors: Sutarih Ayih
Published: August 2019

Kejadian yang merugikan pasien yang dilakukan perawat yang tidak melaksanakanpelimpahan wewenang dari tenaga medis. Rumusan masalahnya adalah bagaimanakahregulasi ,kendala dan solusi, serta sinkronisasi peraturan perundang-undanganpelimpahan wewenang tindakan medis kepada perawat dalam pelayanan kesehatan dirumah sakit. Tujuan penelitian ini untuk menganalisa tentang regulasi pelimpahanwewenang tindakan medis kepada perawat. Penelitian ini menggunakan pendekatanyuridis normatif. Temuan penelitian menunjukkan sudah ada regulasi pelimpahanwewenang tindakan medis kepada perawat,yaitu pada Undang-Undang No. 38 Thun 2014Tentang Keperawatan, Undang-Undang No. 36 Tahun 2014 Tentang Tenaga Kesehatan,dan Permenkes 1239/Menkes/SK/XI/2001 Tentang Registrasi dan Praktek Perawat. Padapelaksaannya banyak mengalami kendala terutama kurang sosialisasi peraturanperundang-undangan yang mengatur pelimpahan wewenang, dan juga ketidaksinkronanperaturan perundang-undangan tersebut. Pelimpahan wewenang tindakan medis kepadaperawat dari pemahaman delegans/mandans yaitu dokter dan delegetaris/mandataris yaituperawat khususnya penyelesaian perkara dan upaya perlindungan pasien (safety patien)perlu ditindaklanjuti riset-riset lanjutan.
AKIBAT HUKUM DOKTER LAYANAN PRIMER DALAM PERANNYA SEBAGAI GATE KEEPER UNTUK SISTEM RUJUKAN BERJENJANG
Authors: Sutrisno Endang , Lambok Betty Dina , Sugiarti Taty , Mulyono Paulus
Published: August 2019

Era Jaminan Kesehatan Nasional (JKN) melalui Badan Penyelenggara Jaminan Sosial (BPJS) telah mereformasi sistem pelayanan kesehatan. Dokter Layanan Primer yang seharusnya berperan sebagai gate keeper di Fasilitas Kesehatan Primer belum menjalankan fungsinya dengan optimal. Fasilitas Kesehatan Primer yang seharusnya dapat menangani penyakit-penyakit dasar dengan tuntas kerapkali mengeluarkan surat rujukan ke rumah sakit, sehingga gate keeper concept dan sistem managed care tidak berjalan sebagaimana mestinya. Kajian pada budaya hukum dokter layanan primer perannya sebagai gate keeper dalam sistem rujukan berjenjang dan upaya untuk meningkatkan kepatuhan hukum. Pendekatan penelitian socio legal research, sebab berkaitan rendahnya kesadaran hukum, pengetahuan hukum, sikap dan perilaku hukum. Budaya hukum yang berupa sikap, anggapan, persepsi, gagasan yang apatis, pragmatis kurang mendukung terlaksananya gate keeper concept dengan baik, dibutuhkan kepatuhan hukum dokter layanan primer melalui pengetahuan hukum dan komunikasi hukum dengan cara sosialisasi, edukasi.