bluuebunny/crossref_metadata_2025 huggingface dataset:
Effect of aqueous extract of Trigonellafoenum-graecum L. seeds on Acetic acid- induced Ulcerative colitis in rats
Authors: Fathima Aqsa , Gangachannaiah Shivaprakash , Bose Ujjal , Prasada Kabekkodu Shama , Chakraborty Rituparna , Kumar S E Praveen , Udupa Padmanabha , Sai Prathap Yadav Rachagolla , Monappa Vidya
Published: July 2023

Background: Ulcerative colitis (UC) is an inflammatory bowel disorder affecting the colonic mucosa, characterized by intense inflammation and mucosal damage. The present study aimed to evaluate the protective effect of the Trigonellafoenum-graecum L. (TFG) seeds in acetic acid-induced UC in rats. Materials and Methods: Male rats (n=30) were distributed into 5 groups as normal control, UC, standard, and two test groups. Colitis was induced by acetic acid in all the groups except the normal control group. Normal control and UC group received distilled water, the standard group was administered sulfasalazine at 100mg/kg body weight (bw), and test groups, TFG-I, and TFG-II received TFG seed extract at 500 and 1000 mg/kg bw, respectively. The duration of treatment was 7 days, and colitis was induced on day 8. Animals were sacrificed on day 9 and colonic tissue was dissected and collected for biochemical, molecular, and histological analysis. Results: The disease activity index score in standard, TFG-I, and TFG-II (3.33±0.21, 2.66±0.21, and 3.50±0.22) was significantly lesser (P<0.05) than scores in the UC group (4±0.01). The macroscopic score indicating the intensity of mucosal inflammation was significantly decreased (P≤ 0.01) to4.0±0.25, 3.16±0.30, and 3.83±0.40 in standard, TFG-I, and TFG-II groups, respectively compared to the UC group (4.66±0.21). Similarly, there was a significant reduction (P≤0.05) in histological scores of the standard, TFG-I, TFG-II (3.5±0.34, 1.25±0.34, 3.25±0.34) groups compared to the UC group (4.75±0.34). Biochemical assessment in the standard and test groups showed significant increase (P<0.05) in total protein, reduced glutathione (GSH), catalase (CAT), superoxide dismutase (SOD) levels whereas significant reduction (P<0.01) in malondialdehyde (MDA) levels compared to UC group. The pro-inflammatory cytokine TNF-α levels were significantly decreased (P<0.01) in standard, TFG-I, and TFG-II (-1.75±0.007, -0.27±0.17 and -0.51±0.002) when compared to the UC group (0.20±0.02). Conclusion: The study demonstrates the ability of TFG seeds in reducing the inflammatory and oxidative stress induced mucosal damage in acetic acid-induced UC in rats.
Isolation and Characterization of a Flavonoid and Analgesic activity of leaves of Bauhinia acuminata Linn.
Authors: Chakraborty Sudipta , Nath Bala Nripendra , Das Sudipta
Published: July 2023

The present study investigated centrally and peripherally mediated analgesic activity of methanol extract of leaves of Bauhinia acuminata and isolation of active compounds by column chromatography with gradient elution using combination of different solvents. FTIR, 1H and 13C NMR spectral data of the isolated compound established it to be a flavonol, quercetin. The analgesic activity of the extract was found to be dose dependent and effective in all the models tested being Acetic acid induced visceral pain model as the best (p<0.01 in all the doses tested). In hot plate method the test extract showed significant analgesia (p<0.01) compared to the control only for 200 and 400mg/kg BWfor all the reaction times tested, but the 100mg mg/kg BW was able to show the same only after 45 min. Formalin induced tonic pain model also exhibited similar results that indicated better analgesia was achieved at late phase (10-30 min). The analgesic activity of this extract may be correlated with that of the available phytochemical data obtained for this plant which indicates the presence of flavonoids and alkaloids as the chief constituents in leaves. In all the test models the results were promising and near to that of the standards used indicating it’s competence in the pain and related therapies which may be validated by further clinical studies.
Determination of Tetracycline residues in red meat available in Oman
Authors: Al- Kindi Sumaiya , Yaqoob ALBalushi Iman Ismail , Abdulalim Elshaar Aisha Yazid , Al Kharusi Ahlam , Al Maimani Razna , Ahuja Alka
Published: July 2023

Tetracycline is heavily used in livestock production either for prophylaxis, treatment or as growth promoter. The residues of tetracycline in animal products have been investigated around the world and linked to imbalance in intestinal microflora, human allergic reactions, and other diseases. Researcher stated that the long term use of tetracycline as sub therapeutic dose increased level of antibiotic-resistant pathogens which is a global threat to human health and food security and development. Many studies reported that the tetracycline levels were above the maximum residual limit1,2. In Oman, few studies have been done using different techniques for investigating the antibiotics levels in animal products. Therefore, the aim of this study was to investigate the tetracycline residues in imported goat meat (liver and muscle) and to compare the levels of tetracycline residues between liver and muscles. A total of 48 fresh muscle and liver samples were taken from 24 Somali goats that were slaughtered at a slaughterhouse in Muscat. The extraction was done using the Agilent Enhanced Matrix Removal—Lipid (EMR—L) product. Four compounds were tested; Tetracycline, Oxytetracycline, Chlortetracycline and Doxycycline. The final extracts were analyzed using LC-MS/MS. The results showed no detection of tetracycline and doxycycline whereas, oxytetracycline and chlorotetracycline were found. 45% of muscle samples had OXY and CTC with concentration range of 6.04-6.23µg/kg and 5.48-8.35µg/kg, respectively. Around 42% of investigated liver samplesshowed OXY and CTC with concentration of 6.04-6.17 µg/Kg and 7.92-8.13µg/kg, respectively. In this study higher concentrations of OXY and CTC were detected in one muscle with values of 403.60035±234.8µg/kg and 274.8491±87.1058, respectively and one liver sample got higher concentration of OXY which was 3201.9±325.1µl/kg. These values were exceeding the MRL GSO 2481/2015, CX/MRL 2-2018 and EU 37/2010. These results might be related to withdrawal time as most of the samples had lower MRL. All samples were studied in triplicates to verify the results and using LCMSMS making data more satisfactory and validated.
Anticancer Activity of Microwave Assisted Polyphenolic Compounds Extracted from Combinations of Curcuma Longa and Camellia Sinensis against Lung Cancer Cell Line
Authors: Jeba R. Caroline , Sandhya G. Abeetha , Das Niranjan , Shau C. Suchoritha , Kumar S. Ajith
Published: July 2023

Objectives: Anticancer activity of microwave assisted polyphenolic compounds was extracted from combinations of Curcuma longa and Camellia sinensisby phytochemical analysis. Invitro anticancer activity was determined by using cell line. Methods: By preliminary phytochemical analysis and using uv-visible spectrophotometer total phenolic content was determined. In vitro anticancer activity was found out by MTT assay method. Result: Phenolic compounds are responsible for antioxidant activity. Plant extracts having hydroxyl groups are responsible for facilitating free radical scavenging. Total phenol content in the plant extract Curcuma longa and Camellia sinensisusing the calibration curve, was found to be 1137.45mg of Gallic acid equivalents/g dry weight of extract. The anticancer activity was carried out with lung cancer cell line (A-549) by MTT assay method. When cancer cells were incubated with combination of curcuma longa and camellia sinensis extracts, they induced cytotoxicity in a significant time which implicit the damage to the membrane integrity of cell. Based on the cell disintegration, when the plant extracts were incubated with lung cancer cells and cell death were calculated. The IC50 value of the given test sample of curcuma longa and camellia sinensisand the standard Cisplatin was found to be 22.72µg and 3.89µg, respectively. This is clearly stated that the selection of A-549 cell line might provide a good evidence for the treatment of lung cancer. Conclusion: Based on the results obtained, combinations of Curcuma longa and Camellia sinensis could be used as an anticancer agent.
Assessment of Genetic relationship among Cannabis sativa L. in Thailand based on ISSR and their Phytoconstituents properties
Authors: Nakkliang Kanittha , Zongram Onuma , Areesantichai Chitlada , Rungsihirunrat Kanchana
Published: July 2023

Due to the long history of prohibition, limited research on Cannabis sativa L., a Thai medicinal plant, remained unexplored for its scientific data to support their medicinal applications. The aim of this study was to assess their genetic relationship among C. sativa collected from different locations of Thailand as well as their phytoconstituents properties. Plant genomic DNA was isolated and genetic relationship was performed based on inter simple sequence repeat (ISSR). Seven out of twenty-five ISSR primers were amplified and yield 993 reproducible banding patterns ranking from 90 - 2,339 base pair in length, of which 99.3% were found to be polymorphic. The dendrogram by Unweighted Pair Group Method with Arithmetic Average (UPGMA) clustered into 2 main clusters. The phytoconstituents analysis of C. sativa ethanolic extract was performed according to the standard method and also their antioxidant property. Phenolic compounds, alkaloids, flavonoids, diterpenes, triterpenes and steroids were presented but not saponin. Total phenolic content assessed by Folin-Ciocalteu’s method was 14.08±0.34mg GAE/g extract while flavonoid content assessed by aluminium chloride was 23.88±0.40mg QE/g extract. Their antioxidant property was assessed using DPPH and FRAP assays expressed in term IC50 was found to be 112.13±0.09μg/ml and 0.228±0.12mM Fe2+/g extract, respectively. The obtained results reveal that ISSR markers could be useful for assessing of genetic relationship of Thai C. sativa collected from various areas and their phytoconstituents properties provided the useful information for their medicinal applications.
Biography of Maulana Lutfullah
Authors:   Alisher Navo'i Tashkent State university of Uzbek language and literature, Sirojiddinov Shuhrat
Published: July 2023

This is a great resource on the life and work, beliefs and religious practices of Maulana Lutfullo Chusti, the great representative of the Naqshbandi dynasty who lived in the 15th-16th centuries after Azam Khoja Ahmed Kosoni. In addition to receiving unrepetitive information about the great children of Uzbek nation, readers make themselves aware of the instructive advice of Uzbek ancestors about honesty, loyalty, kindness, knowledge and ideology.
Turkic ideology and conceptacle artistic basis in the work of Nizami Ganjavi and Alisher Navoi
Authors:   Alisher Navo'i Tashkent State university of Uzbek language and literature, Sirojiddinov Shuhrat , Ashurova Gulbahor
Published: July 2023

In this monograph, the legacy of Nizami Ganjavi and Alisher Navoi, who are the geniuses of world literature and Turkic peoples, their study, artistic and philosophical views of both poets and intellectuals, oriental culture, their contribution to Turkish national cultural heritage, sensitive poetry and two Peculiarities in "Khamsa" are studied.
Importance of Yoga, Yagya, and Ayurveda science in physical, mental, and spiritual health (शारीरिक, मानसिक और आध्यात्मिक स्वास्थ्य मे योग, यज्ञ और आयुर्वेद विज्ञान का महत्व)
Authors:   assistant Professor, Department of Yoga,   Maharishi University of Management and Technology, Bilaspur, Chhattisgarh, India, Sahu Khileshwari , . Dr. Garima ,   Associate Professor, Department of Yoga,   Maharishi University of Management and Technology, Bilaspur, Chhattisgarh, India
Published: July 2023

At present, the whole world is moving forward facing very adverse conditions, this adverse condition was a very serious condition for the human life environment, in which the imagination of a healthy life has become impossible, but if we look at our ancient tradition, Our tradition is full of continuous stream of knowledge of health, in which Yoga, Yagya, Ayurveda diet etc. have an important place. Various scholars have also tried to tell its scientific effects through research etc. In Yoga, Yajna and Ayurveda, various therapies are described to maintain physical, mental, spiritual, health balance and harmony of man. How Ayurveda helps us in fighting spiritual and physical diseases and how it makes us disease-free, etc. Anurag Pandey explains in his research that “Ayurveda, the ancient Indian system of medicine, offers a holistic approach to mental health that integrates the mind, body and soul. Ayurveda is described mental health in Atharva Veda and in subsequent treatises by Charak, Susrut, and Vagbhatt, containing the details of etiology, symptoms, diagnosis, and therapy for afflictions in humans and animals. The science of mental disorders describes extensively conditions from mild anger and greed to severe psychoses. Simultaneously the whole world is looking for the solutions of the inner conflicts afflicting in mental health sector. Ayurvedic theory of mental health is based on combination of The three gunas, tridosha, and panchabhuta, The combination of these doshas and three gunas inherited at birth indicates an individual's called Prakriti. The dynamic balance of these above elements creates a good mental health. Daiva vyaprashraya, Yuktivyapashrya, Satvavajaya cikitsa, Aachara Rasayana, Dinacharya, and Yoga therapy is described in Ayurveda for resolving these ailments.” Key words: Yagya, Yoga, Physical, Mental, Spiritual, Social, Ayurveda.
Performances and economics of weaned rabbits fed varying inclusion levels of Bambusa arundinancea leaf meal (BLM) as replacement for wheat offal
Authors: Wasiu Olaide AKINDELE  , Ayodele Olayinka ADEOSUN
Published: July 2023

Twelve (12) weaned rabbits of mixed breeds were used for a 49days feeding trial to evaluate their performance on a diet containing graded levels of Bamboo leaf meal (BLM) and wheat offal (W/O). Animals in all the treatment groups were fed a partial or total replacement of BLM and W/O at the ratio of 0:100 (TA), 50:50 (TB) and 100:0 (Tc) respectively. All the animals were also served water ad libitum. All the rabbits were randomly assigned to three dietary treatments of 4 rabbits per treatment and 2 per replicates in a completely randomized experimental designs, data were analyzed using a one way analysis of variance and treatment means separated using least significant difference (LSD). Proximate analyses of the tested feedstuffs were carried out at the end of the trial. Performance parameters showed that average feed intake (18,662.89, 19,332.86, 19,220.88, TA TB and TC respectively) and average weight gain (3,050g, 3,230g, 3.460g for TA, TB and TC respectively) were not significantly (P>0.05) different. However TC had the best numerical value among others while the Control (TA) recorded the least. Significant effect (P<0.05) was observed in Feed Conversion Efficiency (FCE) between control group and other groups. Generally, TC recorded the best performance in term of growth and feed utilization. Based on the result of this work, it was concluded that Bamboo leaf meal can be used for rabbit feeding partially or wholly with wheat offal during the long dry season.
Multiple cranial couple syndrome secondary to neurosyphilis: case report
Authors: Silvério Gabriel André , Possan Pedro Arthur , Marchetti Mateus Pinto , Weber Isabela Louise , Terra Vera Cristina , Socher Karen Luiza Ramos , Watanabe Nancy , Caggiano Carlos Cesar Conrado
Published: July 2023

Male, 62-year-old, with Type 2 Diabetes Mellitus, seeks care due to altered balance and worsening palpebral ptosis. The patient had had peripheral facial palsy on the left for 40 days and was treated at another institution with oral prednisone and acyclovir for three days. Ten days ago, he had started with ipsilateral palpebral ptosis, associated with binocular diplopia and divergent strabismus also on the left in the primary gaze position. He also complained that during this period he had worsened visual acuity and frequent falls, which he related to imbalance. Upon inspection, he presented maculopapular erythema on the back, abdomen and upper limbs, with ptosis on the left. On examination, he still had a stomping and dysbasic gait, paralysis of the II, III, and IV nerves bilaterally, as well as of the VII, IX, and X on the left, with reduced visual acuity bilaterally (worse on the left), in addition to a positive Romberg test — with a fall to the left. Furthermore, there was hyporeflexia in the biceps and triceps bilaterally, associated with areflexia in the Achilles and patellas, with symmetrical distal apalesthesia in the four limbs, and cutaneousplantar in bilateral flexion. Magnetic resonance imaging of the head and neck showed uptake by the contrast medium seen at the bottom of the internal auditory canal in the distal meatal and labyrinthine segments of the left facial nerve, without signs of intracranial expansive lesion and without detectable cervical abnormalities. Laboratorially, the patient had a positive treponemal test with a Venereal Disease Research Laboratory (VDRL) value of 1:128 and the serum test for Borrelia burgdorferi showed positivity for immunoglobulin G (with negative immunoglobulin M) on admission, and such tests were repeated and negative prior to discharge, probably being altered due to cross reaction, despite the history of travel for about two years to an endemic area (Canada). Rheumatological tests, tumor and granulomatous disease markers, and serology were negative. When studying the cerebrospinal fluid, we found pleocytosis with lymphomonocytic predominance and hyperproteinorrhachia, with negative VDRL and panel for meningitis. Therefore, the hypothesis of neurosyphilis causing involvement of multiple cranial nerves was suggested and treatment with intravenous crystalline penicillin G was started for 14 days. After the first day of antibiotic therapy, the skin lesions became more prominent (Jarisch-Herxheimer reaction), with spontaneous disappearance in the subsequent days. Even during hospitalization, the patient evolved with gradual improvement of the ptosis on the left, absence of tongue deviation to the right and partial improvement in gait. Intravenous antibiotic therapy was completed, rehabilitation was indicated and outpatient return was planned.
Revaluation of the COVID-19 pandemic impact on the epidemiology of syphilis in Brazil
Authors: Marques Nelson Pereira , Marques Nádia Carolina Teixeira , Silveira Denise Maria , Martelli Daniella Reis Barbosa , Oliveira Eduardo Araújo , Martelli Hercílio
Published: July 2023

Introduction: Due to the coronavirus 2019 disease (COVID-19) pandemic, health systems worldwide have suffered interferences, with the interruption of sexual health clinics, limitation of ambulatory consults, prevention, diagnosis, and treatment of several diseases, especially syphilis, altering their epidemiology.Objective: To investigate the impact of the pandemic on syphilis diagnosis in Brazil, the main goal of this study was to update and reevaluate data from the Brazilian Unified Health System on the number of syphilis cases reported in all five Brazilian geographic regions and verify the response of the Brazilian health care to the COVID-19 pandemic. Methods: The data were retrieved from the National Disease Notification System and the Department of Chronic Conditions Diseases and Sexually Transmitted Infections and represent syphilis diagnosis in Brazil, from March to December 2017 to 2019, 2020, and 2021. Results: The increase in the number of syphilis cases was minor compared to 2020, keeping the Southeast region as the most impacted (+146.1%) and an increase of 22,633 cases throughout Brazil (+54.3%). Conclusion:Syphilis disease control measures were ineffective in 2021 as the drop in the number of cases was irrelevant compared to the years before the pandemic. The association between the increase in syphilis cases in Brazil and the COVID-19 pandemic should be further investigated to assist in decision-making processes and in the programming of health actions in addition to finding measures to raise the control of this disease.
Prevalence of early hospital readmissions in a reference unit for the treatment of people living with HIV located in Ribeirão Preto, Brazil
Authors: Santana Rodrigo de Carvalho , Oliveira Lígia Maria Silva de
Published: July 2023

Introduction: The 30-day readmission rate after discharge has been used to indicate healthcare quality. However, precise data on this indicator are still scarce in Brazil, especially among people living with HIV. Objective: The objectives of this study were to describe the rate of early hospital readmissions in people living with HIV and the sociodemographic and clinical characteristics of readmitted patients and to identify the factors associated with readmissions. Methods: This prospective cohort study was conducted with patients admitted between August 2016 and August 2018 in a university hospital in the state of São Paulo, Brazil. Clinical and laboratory data, social indicators, use of illicit drugs, and adherence to antiretroviral treatment were evaluated. Participants were monitored for hospital readmissions within 30 days after discharge from the index hospitalization. Results: A total of 71 patients were included. There was a predominance of men aged between 30 and 60 years, with low socioeconomic and educational levels, inadequate control of HIV infection, and frequent use of psychoactive substances. The 30-day readmission rate found was 22%. Gastrointestinal diseases were the most frequent in index hospitalizations and early readmissions. Conclusion: The early readmission rate in people living with HIV was 22%. Gastrointestinal diseases were the most prevalent in the index of hospitalization and early readmissions. Most of the patients admitted and readmitted are middle-aged men with a low level of education, low insertion in the labor market, a considerable rate of psychoactive substance use, and living in conditions of social vulnerability.
Comparative study of ultrasound abdomen and pelvis with CT urography in diagnosis of benign causes of Hematuria
Authors: Saurabh Pandey  , Vishal Gupta  , Fathima Febin Salu  , Bommu Prateek  , Sumit Kumar  , Parnit Kalra
Published: July 2023

Background: The presence of more than or equal to 3 RBC/HPF in the sediment is defined as haematuria. It can be symptomatic or asymptomatic. Painless haematuria is most often caused by carcinoma, while painful haematuria is often seen secondary to urolithiasis or infection. The procedure entailed in detection of microscopic haematuria and gross haematuria is the same. But in the microscopic haematuria the focus is on the glomerular causes. In the diagnosis of haematuria radiology plays a very important role. Radiological investigation of upper urinary tract is usually by IVU but has been gradually replaced over the last decade by MDCT Urography as the gold standard imaging modality. CT-Urography (CTU) can accurately identify benign causes of haematuria in about 33-43% cases. The overall sensitivity is 92-100% is for identifying benign causes, while 89-97% gives the specificity for benign causes, especially calculi. Hence, we performed a study to compare the CT and USG findings for haematuria. Methods: The study included 50 of the patients diagnosed with microscopic or macroscopic haematuria and those above the age of 18 years. We excluded those patients with patients whose serum creatinine value was above 1.5 mg/dL, those that are at a risk for allergic reactions to contrast, those with neoplasms and pregnant patients. Results- In the present study, we found that the sensitivity and specificity of USG was 87.92% and 86.52% respectively. However, for CT urography, it was 97.62% sensitivity and 92.34% specificity. This shows that CT is more sensitive for identifying benign lesions in the KUB region as compared to USG. Conclusion- CT urography is more sensitive and specific for benign lesions when compared to USG.
Yağda Çözünen Vitaminler ve Bağırsak Mikrobiyotası Üzerine Etkileri
Authors: KARAAĞAÇ Rabia Melda , PINARLI Çağla
Published: July 2023

Sağlığın ve hastalığın kilit düzenleyicisi olarak mikrobiyota, son zamanlarda popüler konulardan birisidir. Başta deri, ağız, solunum sistemi ve gastrointestinal kanal olmak üzere farklı vücut bölgelerinde mikrobiyota bulunmaktadır. Bağırsak mikrobiyotası, immün-modülasyon, konağın besin metabolizmasını düzenleme gibi pek çok etkisi bulunmaktadır. İnsan bağırsak mikrobiyotasının oluşumunda yaşamın erken dönemleri, özellikle ilk 3 yaş ön plana çıkmaktadır. Bağırsak mikrobiyotası, konağın normal fonksiyonlarını devam ettirmesinde ve işleyişinde önemli bir rol oynamaktadır. Bununla birlikte bağırsak mikrobiyotası, konak ile etkileşime girerek insan sağlığını olumlu veya olumsuz etkileyen çeşitli metabolik ürünleri sentezleyebilmektedir. Bu noktada vitaminler de çeşitli mekanizmalar yoluyla mikrobiyomu modüle etmektedirler. Vitaminler, vücutta birçok işlevi olan çok çeşitli moleküllerdir. Vitaminler, yağda çözünen ve suda çözünen vitaminler olarak iki temel sınıflana ayrılmaktadır. Vitaminlerin bağırsak mikrobiyotasındaki dolaylı etkileri arasında; konak bağışıklık tepkisini etkileme, enfeksiyonlara duyarlılığı değiştirme gibi şeyler bulunmaktadır. Mikrobiyom aynı zamanda bir vitamin üreticisidir, bu nedenle mikrobesin ögesi yeterliliğine ve bağırsaktaki bakteri topluluklarının stabilitesine katkıda bulunmaktadır. Tüm bu sebeplerle vitaminler, enerji kaynağı olarak kullanılmadan bağırsak mikrobiyomu üzerinde çift yönlü, doğrudan veya dolaylı etkilere sahip olabilmektedir. Bu çalışmanın amacı, yağda çözünen A, D, E, K vitaminlerinin bağırsak mikrobiyotası üzerine etkilerini literatür bilgileri ışığında derlemektir.
Healthcare Industry Jobs: Opportunities and Challenges from a Student's Perspective
Authors: Banerjee Rupa
Published: July 2023

This publication explores the opportunities and challenges that students encounter in pursuing healthcare industry jobs from their distinctive perspective. The healthcare sector offers a wide range of career possibilities, encompassing clinical and non-clinical roles, which attract students seeking to contribute to the field. However, students face numerous challenges when navigating this ever-evolving landscape. On the one hand, the healthcare industry presents significant opportunities for students. Advancements in medical technology, a growing emphasis on patient-centered care, and the expanding healthcare needs of aging populations create a demand for skilled professionals. Additionally, emerging fields such as digital health and genomics offer novel prospects for students to innovate and drive positive change. On the other hand, students encounter challenges in accessing healthcare industry jobs. Fierce competition for coveted positions, complex regulatory frameworks, and the need to stay updated with evolving healthcare policies pose obstacles for students. Furthermore, the rapid integration of technology in healthcare necessitates students to acquire digital literacy and adapt to new workflows.
Spectral Variability of the Symbiotic Star CH Cyg
Authors: Mikailov Khidir Mustafa  , Mammadov Ruslan Tavakkul  , Rustamov Bayram Nizam  , Rustamova Aysel Bayram
Published: July 2023

On July 15, 2015, the second telescope of the Shamakhi Astrophysical Observatory (ShAO) was used to collect 14 echelle spectra of the symbiotic star CH Cyg over the course of six hours of nocturnal exposures. Along the profiles of the lines Нα and Нβ, the intensity of line Hel λ5876 Å fluctuates simultaneously with variations in the intensity ratios of the blue and red emission components. The Hel λ5876 Å line’s center intensities and corresponding widths correlate with information from the blue emission component of the lines. There are certain correlations between the radial velocities of the absorption DNaI and the emission line Нα.
Automated Design Using Machine Learning in Materials Engineering - An Explicit Forecasts
Authors: Guomundsson Birgir , Lorna Gunnar
Published: July 2023

Every discipline of physics, including materials science, has been profoundly influenced by the arrival of
algorithmic breakthroughs in the domain of machine learning. Many important advances have been made by combining
materials data (computed and measured) with different machine learning approaches to solve difficult problems like,
creating effectual and extrapolative surrogate prototypes for a wide variety of material parameters, down-selecting and
screening novel candidate materials for particular application, and structuring novel approaches to accelerate and enhance
atomistic and molecular simulations. Although current implementations have shown some of the promise of data-enabled
pathways, it has become evident that success in this area will depend on our capacity to interpret, explain, and justify the
results of a machine learning approach on the basis of our professional knowledge in the field. This article reviews the
most important machine learning applications in materials engineering. In addition, we present a short overview of a
number of methods that have proven useful in deriving physically relevant insights, design-centric knowledge, and causal
links from materials engineering. Last but not least, we highlight some of the next prospects and obstacles that the
materials community will encounter in this dynamic and fast developing industry.
Teacher’s Lesson Plan In Lesson Study Context In SMP Cokroaminoto Palopo
Authors: Rahmawati Upa  , Hermini
Published: July 2023

Lesson Plan is one of the most important element in teaching. It is the teachers’  road map of what students need to learn and how it will be done effectively during the class time. Due to its importance, in this research, the researcher try to conduct a research relaed to the teachers’ lesson plan in Lesson Study in SMP Cokromnito Palopo. This research is itended to  describe how the teacher’s lesson plan in SMP Cokroaminoto Palopo. This reseach was done trough Lesson Study activities so the lesson plan described is Lesson Study context. This research employed qualitative research and applied descriptive study. The teacher was choosen as the subject of this research was the English teacher of SMP Cokroaminoto Palopo. She taught seven grade and the researcher observed two cycles planning. The research instrument were direct observation, video recording and teacher’s lesson plan. After analyzing the research, then the researcher can conclude that there are some aspects can be found from the Lesson Plan after pnanning for two cycles. They are : the teacher plan to use  cooperative learning method,  Learning media (memo paper, word card, and LCD), Assessment (teacher assessment), Students’ seating arrangement (U shape).
The Effectiveness of Picture Series in Improving Students’ Writing Skill at Mega Buana University
Authors: Tri Endar Yogi Setiadi Saputra
Published: July 2023

This research has two variables, namely the students’ writing skill as independent variable and picture series as dependent variable. The aim of the research is to find out the effectiveness of picture series in improving students’ writing skill at Mega Buana University. The research applied Pre-Experimental method, where the students were given both pre test and post test. The population of this research is the Fourth Semester Students of Midwifery Study Program at Mega Buana University with the total of population are 42 students. The researcher chose 15 students as sample. The sample was taken by using purposive sampling technique. The result of this research showed the probability was 0.000 < 0.05. Based on this fact can be showed that H0 was rejected. Therefore there was different mean score of pre test and post test in this class. By looking at this result, can be understood that picture series was effective to improve students’ writing skill.
An Appraisal of Cai Yong’s Fu from His Innovations
Authors: Zelei LIAN
Published: July 2023

Cai Yong is one of the most accomplished and prolific fu writers in the Han dynasty, whose fu oeuvre as a whole greatly expands the scope of traditional fu writing and re-defines fu as a literary genre with his constant experiments with both form and content. Embedded with his life as is recorded in his official biography and modern scholarship, this paper re-evaluates Cai Yong’s fu from his innovations, and argues that there are four innovations that can be firmed established in his fu: 1 the broadening of the scope of fu, enabling it to convey more emotions than only frustration; 2, direct engagement with politics of his time; 3, his metrical innovations in the rhythm of fu; 4, his creative borrowing from the Shi jing.
The Negotiation Process of Indo-Pacific Economic Framework and Its Alliance Turning
Authors: Zhuo WANG
Published: July 2023

The United States launched the “Indo-Pacific Economic Framework” in May 2022, which is an important part of its “Indo-Pacific Strategy” in the economic field. As representatives, experts, ministerial meetings and formal negotiations continue, the tendency of the United States and its allies to establish a political and economic integration alliance to encircle China in the Asia-Pacific region has become increasingly apparent. The purpose of this paper is to study China’s response, how to hold high the banner of peace, development, cooperation, and win-win, promote high-level opening up, and achieve Chinese path to modernization on the path of peaceful development. Through the detailed analysis of the negotiation process and other research methods, it is suggested that in the short and long term, we should focus on the rapid realization of the equal opening of IPEF and the establishment of a community with a shared future for mankind.
The Compatibility Characteristics of Confucian “Great Harmony Society” and Communist Ideal
Authors: Chuanqing ZHANG , Yingxin LI
Published: July 2023

In order to continue to promote the Sinicization of Marxism, we must further improve the work of combining Marxism with China’s specific reality and excellent Chinese traditional culture. The Confucian culture represented by Confucius’ thought has a high degree of self-consistency and compatibility between its excellent spiritual connotation of “the society of great harmony” and the lofty ideal of communism. These self-consistency, and compatibility characteristics mainly include the compatibility between Confucius’ “the world is for all” and communist public ownership; the compatibility between Mencius, “rule of the people” and Marxist “individual ownership”; the compatibility between Confucian “ practice learning” and Marxist practice view; the compatibility between “sages,” “gentlemen” “ key minorities” and “communists” and the compatibility between Confucian rational spirit and Marxist “atheism” thought. A profound understanding of the compatibility between the two has important practical significance for improving our cultural self-confidence and promoting and developing Marxism in China.
A Study on Taiwan-related Public Opinion and Its Attitude Differences Among the Netizens of Chinese Mainland: An Analysis of the Topic of “Seeking Independence by Epidemic” on Weibo
Authors: Ruxiang HU , Chiadong CHEN
Published: July 2023

This study explores the timing of the outbreak of Taiwan-related public opinion and the corresponding public opinion events among mainland microblog netizens under the theme of “seeking independence through the epidemic”. Utilizing the “interpretation package” theory, “encoding/decoding theory,” and emotional polarity analysis, the study establishes a framework for analyzing netizens, sentiment in terms of priority, negotiation, and confrontation. The study extracts five distinct emotional differences in national identity, including “acknowledging the legitimacy of the Chinese central government and actively participating in the formation of national identity, “having strong confidence in China’s military power,” displaying “nationalistic and resolute views on sovereignty issues,” “disapproving of certain harmful policies and subjects,” and “patriotic sentiments fueled by Internet populism.”
Translating Chinese Texts of Intangible Cultural Heritage into English from the Perspective of an Integrated Strategy
Authors: Shaodong JIA , Qiulan ZHAI
Published: July 2023

This paper centers around exploring translating Chinese introductory texts into English concerning the intangible cultural heritage of Guangdong Province and Hainan Province. Based on analyzing the textual features of the Chinese texts, the paper puts forward the principles of two types of closeness and five Cs in terms of translating the original text that serves the informative and vocative functions. Then in accordance with the two translation principles, an integrated strategy has developed on the basis of alienation, adaptation and compensation for contextual and cultural default so as to render the source texts into perfect English. Specifically, with the guidance of the principles and the integrated strategy, this research focuses on how to translate text titles, sentences with unique culture-specific items and short passages by employing such methods as transliteration, transliteration plus literal translation, transliteration plus annotation, addition or supplement, interpretation, intra-text annotation, condensation, and substitution, etc. The integrated application of the strategies and methods does work to retain the original culture in the translated text, and on the other, makes the translated versions content-centered, culture-oriented, concise, clear and coherent both in form and in meaning, thus achieving the goal that the translated text should be closer to the cultural characteristics of the source text and closer to the thinking mode of target readers. It is hoped that this exploration will make contributions to the translation research into the texts in relation to the intangible cultural heritage of China.
Curriculum Innovation of University Fine Arts Major Under the Strategy of “Double-Carbon”: Take The Comprehensive Art Major Curriculum As An Example
Authors: Chunhan DAI
Published: July 2023

Taking the analysis of the fine arts course in colleges and universities as a start, this paper proposes solutions to the problems like generalization, fragmentation and closure problems that are found in the course. The development of the art theory of green and low-carbon materials is taken as the carrier, and this paper expounds the basic paradigm and value orientation of comprehensive art major courses in colleges and universities, which breaks the traditional discipline barrier and puts forward the course cultural assumption of creating a multi-ecological civilization. This study expands the development horizon of art disciplines and provides valuable reference for the course setting of integrated arts majors in colleges and universities under the practice of “double carbon” strategy.
Perkembangan Anak Usia Dini dalam Pendidikan Kristiani Ditinjau dari Teori Piaget
Authors: Monica Maria Agnes
Published: July 2023

This study intends to analyze early childhood development in Christian Education. Early childhood development in Christian Education is an important basis for child development. The method used in this study is qualitative with a literature study approach. Research findings reveal that Christian values in early childhood learning are important to be given as a foundation for the formation of attitudes and socio-psychological development of children. In this regard, Christian education needs to take a role in explaining, complementing, undertaking, directing and helping children grow in knowledge of attitudes and actions based on Christian values.

Penelitian ini bermaksud untuk menganalisis perkembangan anak usia dini dalam Pendidikan Kristiani. Perkembangan anak usia dini dalam Pendidikan Kristiani menjadi dasar penting dalam perkembangan anak. Metode yang digunakan dalam penelitian ini ialah kualitatif dengan pendekatan studi literatur. Temuan penelitian mengungkapkan bahwa nilai-nilai kristiani dalam pembelajaran anak usia dini penting untuk diberikan sebagai landasan pembentukan sikap dan perkembangan sosial-psikologi anak. Dalam hal ini, pendidikan kristiani perlu mengambil peran dalam menjelaskan, melengkapi, menyanggupkan, mengarahkan dan membantu anak bertumbuh dalam pengetahuan sikap dan perbuatan berdasarkan nilai-nilai Kristiani.
Strategi Pelaksanaan Pembelajaran Pendidikan Agama Kristen Di Era Digital
Authors: Rudie Rudie , Sihombing Octamaria
Published: July 2023

This study aims to describe the form of implementation of digital era Christian Religious Learning at Palangka Raya Christian High School. To reveal the purpose of the study, this research method is qualitative descriptive research. The results of the study revealed that the form of implementing Christian Religious Education learning online (online) using the WA application (WhatsApp), Classroom, and Zoom meetings. The strategy for implementing teacher learning for Christian religion subjects in Christian high schools is an expository learning strategy, problem-based and cooperative learning strategy. Its application is arranged alternately and which is a consideration of whether or not the material is appropriate with the learning strategies used. The implementation of the implementation of the learning strategy has not been carried out consistently, which is indicated that it has not fully met the provisions as in the application of the learning strategy.

Penelitian ini bertujuan untuk mendeskripsikan bentuk pelaksanaan Pembelajaran Agama Kristen era digital di SMA Kristen Palangka Raya. Untuk mengungkapkan tujuan penelitian tersebut, maka metode penelitian ini adalah penelitian deskriptif kualitatif. Hasil penelitian mengungkapkan bahwa bentuk pelaksanaan pembelajaran Pendidikan Agama Kristen secara online (daring) dengan menggunakan aplikasi WA (WhatsApp), Classroom, dan zoom meeting. Strategi pelaksanaan pembelajaran guru mata pelajaran agama kristen di SMA Kristen yaitu strategi pembelajaran ekspositori, berbasis masalah dan strategi pembelajaran kooperatif. Penerapannya diatur secara bergantian dan yang menjadi pertimbangan apakah materi itu sesuai atau tidak dengan strategi pembelajaran yang digunakan. Pelaksanaan penerapan startegi pembelajaran tersebut, belum terlaksanan secara konsisten, yang ditandai belum sepenuhnya memenuhi ketentuan-ketentuan sebagaimana dalam penerapan strategi pembelajaran tersebut.
Success Factors in Adopting AI in Human Resource Management in UAE Firms: Neutrosophic Analysis
Authors:   American University in the Emirates, UAE, Bettayeb Abderrahmane ,   Tashkent State University of Economics, Uzbekistan, Balbaa Muhammad Eid
Published: July 2023

The revolutionary breakthroughs of artificial intelligence (AI) are swiftly and extensively invading many domains of human activity, serving as the central driving force of the next wave of informatization progress and industrial revolution. Although artificial intelligence (AI) technology and apps have been extensively explored, and variables affecting AI acceptance have been found, the influence of success factors on the acceptance of AI is still unclear. Thus, this study presents a methodology to investigate the effects of gadgets, organizations, and ecosystems on the acceptance of AI in Human Resource Management (HRM) in the UAE. This study used a neutrosophic set (NS) to overcome the vague information. The NS is integrated with the AHP method to rank the success factors in adopting AI in HRM in UAE. The AHP method is used to give importance to these factors. This study used 12 factors in UAE to rank it by the N-AHP.
Why HBCUs Must Create World-Class Doctor of Business Administration (DBA) Programs
Authors: Caldwell Cam , Gasman Marybeth , Rutledge Tangela
Published: July 2023

Historically Black Colleges and Universities (HBCUs) have provided opportunities for Black students to obtain an education together with people of common backgrounds and have done a great deal to prepare those students for success. This paper identifies why HBCUs must now raise the bar in offering world-class doctoral level educational opportunities that can exponentially improve the quality of business schools, better prepare business graduates, and increase the prestige of business programs at those institutions.
Advancing professionalization in human simulation: perspectives of SP educators from around the world on the Association of SP Educators Standards of Best Practice
Authors: Brem Beate G , Hoelzer Henrike , Blatt Benjamin , Ruba Emily , Miller Jane L , Smith Cathy M
Published: July 2023

Between 2013 and 2017, the Association of SP Educators (ASPE), a global organization of educators dedicated to the work of human simulation, developed Standards of Best Practice (SOBP) for working with human role players in simulation. These individuals are known by diverse terms, including simulated or standardized patients or participants (SPs). This study had two aims: (1) to understand the ways in which the ASPE SOBP are relevant to the practices of SP educators around the world, and (2) to identify improvements to the ASPE SOBP from a global perspective.

This qualitative study was undertaken between January 2020 and July 2022. Subjects consented to audio-recorded interviews. A collaborative, inductive coding approach was adopted, followed by thematic analysis, aligned with the methods described by Braun and Clarke. Themes were further updated following reflexive conversations amongst the investigators at meetings over the course of several months and were aligned with the study aims.

Twelve SP educators from six continents participated. Four primary themes were identified (each with multiple subthemes): influencing SP educator practices; advancing professionalization; identifying challenges to implementation; and bridging gaps in the ASPE SOBP.

A diverse group of SP educators from around the world identified the ASPE SOBP in general as relevant and applicable to their practice. The standards provided both guidance and flexibility for working with SPs in a safe, effective and quality-based way. At the same time there were challenges noted and recommendations made that can help to inform future iterations of the standards.
Paediatric cardiopulmonary resuscitation quality during simulation of in-hospital transport
Authors: Bibbens Sara E , Lam Anne K , Lam Fong W , Bastero Patricia , Lasa Javier J , Doughty Cara B
Published: July 2023

In-hospital cardiac arrests that occur outside of the intensive care unit may require transportation during active cardiopulmonary resuscitation. Studies have shown that high-quality cardiopulmonary resuscitation is imperative for survival with preserved neurologic function. We sought to determine if high-quality cardiopulmonary resuscitation is maintained during simulated transportation of paediatric in-hospital cardiac arrest.

Randomized crossover simulated study of paediatric in-hospital cardiac arrest with 10 teams composed of five providers (physicians, advanced practice providers, nurses and respiratory therapists). Teams remained in a simulation room or transported the mannequin between two rooms. The primary analysis compared chest compression fraction in stationary versus transport simulations. Secondary analyses included additional cardiopulmonary resuscitation quality metrics with comparison to the 2015 American Heart Association standards.

There was no significant difference in chest compression fraction or rate between the transport and stationary groups. 92%, 72% and 26% of epochs met American Heart Association criteria for compression fraction, rate and depth, respectively. Stationary simulations were more likely to meet recommendations for combined quality metrics, including compression fraction and rate (77 vs. 53;

Chest compression fraction was preserved during simulated in-hospital cardiac arrest with transport. However, the transport simulation was less likely to meet American Heart Association recommendations for combined metrics. Similar to previous cardiopulmonary resuscitation quality studies, both teams failed to meet depth requirements in the majority of simulations.