bluuebunny/crossref_metadata_2025 huggingface dataset:
Amiloidose cardíaca
Authors: Costa Mariana Zamprogno da , Barenco Bárbara Pires de Mello , Barenco Bettina Pires de Mello , Siqueira Emílio Conceição de
Published: April 2023

Objetivo: Analisar as características da Amiloidose Cardíaca (AC). Revisão bibliográfica: A amiloidose cardíaca resulta de oligômeros amiloides circulantes citotóxicos e fibrilas amiloides que distorcem a estrutura do tecido cardíaco, resultando em espessamento e enrijecimento das paredes ventriculares com insuficiência cardíaca e disfunção condutiva. Existem duas proteínas amiloidogênicasresponsáveis por mais de 95% dos acometimentos cardíacos: a amiloidose por cadeia leve (AL) e a amiloidose por transtirretina (ATTR) que se subdvide na forma hereditária (ATTRm) ou adquirida (ATTRwt). Enquanto a AL resulta da produção excessiva de cadeias leves de anticorpos que se dobram incorretamente e se depositam nos tecidos, a ATTR é causado pela deposição extracelular de monômeros de transtirretina mal dobrados.Considerações finais: A amiloidose cardíaca éconsiderada uma causa rara, mas subdiagnosticada de cardiomiopatia restritiva que se não tratada tem curta sobrevida para as suas duas proteínas desencadeantes. Nesse sentido, deve-se ter alta suspeição para AC em pacientes com IC com fração de ejeção preservada, hipertrofia ventricular esquerda inexplicável e envolvimento de órgãos sistêmicos, podendo ser diagnosticada de forma não invasiva por ecocardiografia, ressonância magnética cardíaca ou cintilografia nuclear.
Alterações eletrocardiográficas nos pacientes portadores da COVID-19
Authors: Vieira Eliano Atanázio , Vilagra Sandra Maria Barroso Werneck
Published: April 2023

Objetivo: Reconhecer as alterações no eletrocardiograma nos pacientes portadores da COVID-19. Métodos: Trata-se de uma revisão integrativa de literatura em que foi realizado uma busca por trabalhos nas plataformas PubMed, Medline e DOAJ e um total de 25 artigos foram incluídos no trabalho científico após a aplicação dos critérios de inclusão e exclusão. Resultados: Por meio dos estudos realizados foram observados que as principais alterações nos ECG dos enfermos foi a alteração do segmento ST, alargamento do complexo QRS, inversão da onda T, e alargamento do intervalo QTc, essas alterações estão relacionadas com o alto risco de arritmias. Além disso, o processo fisiopatológico está associado com o uso de medicamentos administrados, inflamação do próprio vírus e da resposta exacerbada do organismo na liberação de citocinas. Considerações finais: Em consideração, essas variações eletrocardiográficas são decorrentes da terapia medicamentosa instaurada, excesso de citocinas e inflamação direta do vírus, essas alterações implicam diretamente no prognóstico de cada paciente.
Intervenções cirúrgicas das fístulas anais
Authors: Cabral Fernanda Carolina Bindá , Olivares Alice Vitória Oliveira de , Pereira Ana Clara Verônica , Gouvêa Celine Almeida , Murad Gabriela Abreu , Ribeiro Gabriela Mello Cerqueira , Ramos Sarah Aparecida Moreira , Soares Thaís Helena Veloso , Alves Adrissa Alana Carneiro , Moura Ariany de Assis
Published: April 2023

Objetivo: Reunir dados acerca das intervenções cirúrgicas realizadas para o tratamento de fístulas anais. Métodos: Revisão integrativa com coleta de dados pela plataforma do PubMed. A partir dessa pesquisa, foram encontrados 170 artigos e selecionados 17 artigos completos. Excluíram-se os artigos que não corroboram com o tema, não tinham veracidade ou não apresentavam dados relevantes para este estudo. Resultados: A abordagem terapêutica para o tratamento de fístulas anais ocorre, em geral, por meio de intervenções cirúrgicas, tendo como objetivo a eliminação do trajeto, prevenção de possíveis doenças e preservação da função esfincteriana. A escolha da melhor técnica cirúrgica dependerá de fatores como complexidade e etiologia da fístula, podendo ser fistulotomia em um ou dois tempos e Vídeo Assistido de Fístula Anal (VAAFT), visto que é um procedimento minimamente invasivo e altamente eficaz para as fístulas anais complexas, apresentando baixa taxa de recidiva. O ultrassom anorretal tridimensional apresentou importância diagnóstica mapeando e quantificando precisamente o comprimento dos músculos, atuando na classificação das fístulas, além de evitar intervenções cirúrgicas desnecessárias, bem como identificando possíveis recorrências após o tratamento.  Considerações finais: Considera-se a relevância de uma detalhada investigação etiológica a fim de proceder com a técnica cirúrgica mais eficaz e conservadora.
Os efeitos da Fridericia chica no estresse oxidativo
Authors: Freitas João Manoel Rodrigues de , Reis Ciro Luiz Fernandes , Carvalho Cristopher Mateus , Vale Gabriel Tavares do
Published: April 2023

Objetivo: Identificar a literatura científica que investiga e indica os efeitos antioxidantes e citoprotetores da Fridericia chica (Bonpl.) L.G. Lohmann, espécie amazônica conhecida popularmente como crajuru, cipó-cruz e pariri e utilizada na medicina popular para o tratamento de diversas afecções à saúde humana, como processos infecciosos e inflamatórios, afecções gastrointestinais, câncer, hipertensão e anemia. Revisão bibliográfica: Foram encontrados 17 artigos. O texto de cada artigo encontrado foi avaliado integralmente, a fim de selecionar apenas os trabalhos de interesse, que analisassem o potencial antioxidante da espécie em questão. Após aplicação do critério de inclusão e exclusão, resultaram 7 artigos utilizados para a revisão de literatura. Estudos indicam que a F. chica possui compostos antioxidantes e protege as células do organismo. Além disso, pode diminuir os níveis de transaminases, estresse oxidativo e toxicidade hematológica. Considerações finais: Pode-se afirmar que a F. chica possui compostos com propriedades antioxidantes e citoprotetoras, e pode ser uma fonte potencial para o desenvolvimento de fármacos com impacto na saúde pública.

Palavras-chave: Fridericia chica, Ação Antioxidante, Estresse Oxidativo.
Complicações dos Métodos DIEP e TRAM na reconstrução mamária
Authors: Brittes Carlos Filipe Teixeira , Maia Lucineide Martins de Oliveira
Published: April 2023

Objetivo: Analisar e esclarecer as principais complicações dos métodos Retalho do Músculo Reto Abdominal (TRAM) e Retalho de perfurante da Artéria Epigástrica inferior (DIEP) na reconstrução mamária em pacientes após tratamento de câncer de mama. Métodos: Para realização do trabalho foram feitas duas etapas utilizando as bases National Library of Medicine (PubMed) e a Portal Regional da Biblioteca Virtual em Saúde (PR-BVS), com os descritores “Breast reconstruction”, “DIEP Flap”, “Complications” para a primeira etapa e “Breast reconstruction”, “TRAM” e “Complications” para a segunda etapa. Foram incluídos artigos com texto completo, em inglês, do tipo ensaio clínico e ensaio clínico randomizado e excluídos aqueles que estavam duplicados ou fugiram do tema. Resultados: Através dos estudos analisados foram encontradas complicações mais incidentes quando somados a fatores de risco, dentre elas a necrose tecidual e hérnias incisionais e algumas menos incidentes, mas com maior severidade como a embolia pulmonar e trombose venosa profunda. Considerações Finais: Observa-se que para que as complicações sejam minimizadas ou evitadas o médico deve ter uma boa técnica operatória e fazer um bom acompanhamento pré e pós-operatório.
Avaliação do desenvolvimento biopsíquico de crianças sob tutela
Authors: Araujo Gabriela Arantes , Salazar Geovanna Camargo , Julião Karoline Mariane , Jabbar Rafael , Aquino Neto Rafaella Lorrayne , Mendonça Pedro Humberto Rassi de , Silveira Marluce Martins Machado da , Macedo Juliane
Published: April 2023

Objetivo: Avaliar se a condição de tutela afeta o desenvolvimento físico e/ou psicoemocional em crianças em um município do estado de Goiás. Métodos: Trata-se de estudo transversal e descritivo, conduzido com 7 participantes, de ambos os sexos, idade de 5 a 10 anos, residentes em orfanatos da cidade. Os dados físicos das crianças foram coletados e analisados através das curvas de estatura e peso em relação à idade e Índice de Massa Corporal (IMC) em relação à idade. Para a avaliação do desenvolvimento psíquico, houve a aplicação da Escala de Traços de Personalidade para Crianças (ETPC). O estudo foi aprovado pelo Comitê de Ética em Pesquisa. Resultados: A amostra, com média de idade de 7,9 ± 1,4 anos, apresentou maioria masculina (57,1%). Com relação aos dados físicos, 72% apresentaram altura adequada para idade, 86% peso adequado para idade e 57% sobrepeso e obesidade. Os dados psicológicos revelaram aumento dos parâmetros extroversão e neuroticismo, redução do psicoticismo e normalidade na sociabilidade. Conclusão: Conclui-se que crianças sob tutela em Anápolis-GO apresentam alterações do desenvolvimento físico e/ou psicoemocional.
Fitoterapia Chinesa no tratamento complementar da Síndrome Metabólica: uma revisão sistemática
Authors: Campos Leidiomar da  Silva , Soares Letícia Guimarães , Leonel Camila Ferreira Silva , Rosa Rosane Dias da , Byk Jonas
Published: April 2023

Objetivo: Descrever a relação dose - resposta do efeito da ação terapêutica da Fitoterapia Chinesa como tratamento complementar ou isolado na Síndrome Metabólica (SM). Métodos: A busca da literatura foi realizada nas bases de dados MEDLINE/PubMed, Embase, Cochrane, BVS e ClinicalTrials.gov. A literatura cinzenta foi pesquisada no Google Scholar e Scopus. A análise metodológica e risco de viés foram realizados através da ferramenta Risk of Bias (RoB2) tool da Cochrane, e análise das limitações metodológicas através do CASP Randomised Controlled Trial Standard Checklist. A análise da evidência qualitativa foi realizada através do GRADE-CERqual.  O protocolo desta revisão sistemática foi registrado no PROSPERO com CRD42021281682. Resultados: Nove ensaios clínicos randomizados, todos revisados por pares, foram incluídos nesta revisão para a síntese qualitativa. Em 88,8% dos estudos incluídos a Fitoterapia Chinesa demonstrou exercer um efeito benéfico no controle da SM. Quanto a análise da evidência qualitativa os estudos apresentaram confiança de moderada a baixa. Considerações finais: A Fitoterapia Tradicional Chinesa pode controlar a SM, quando usada de forma complementar ou isolada. Todavia, o mecanismo de ação desses fitoterápicos ainda precisa ser mais investigado por ensaios clínicos em larga escala.
BAURAN KEBIJAKAN FISKAL DAN MONETER TERHADAP PEREKONOMIAN DALAM PERSPEKTIF SYARIAH
Authors: Okri Handoko Dodi , Putra Popi Adiyes , Ismail Rifki , Soemitra Andri
Published: April 2023

Kebijakan moneter dan kebijakan fiskal merupakan kebijakan yang mempengaruhi kebijakan ekonomi makro. Penetapan kebijakan ekonomi secara makro akan memberikan dampak pada pencapaian peningkatan ekonomi. Agar pertumbuhan ekonomi sesuai dengan yang diharapkan, maka kebijakan moneter dan fiskal harus berjalan saling beriringan dan saling mendukung. Jika kedua kebijakan itu saling berlawanan dan tidak saling mendukung, maka pertumbuhan ekonomi akan terganggu atau malah mencapai nol. Oleh karena itu diperlukan interaksi dan interkoneksi antara kebijakan moneter dengan kebijakan fiskal. Kedua lembaga pemerintah yang berwenang menangani masalah keduanya, baik Kementerian Keuangan sebagai penanggung jawab kebijkan fiskal maupun Bank Indonesia sebagai pemegang mandat dalam menetapkan kebijakan moneter, harus bisa menyatukan kebijakan-kebijakan demi mendorong pertumbuhan ekonomi yang mensejahterakan rakyat.
Assessment of Alkaline Phosphatase in Crevicular Fluid of Adolescent Undergoing Rapid Maxillary Expansion
Authors:   de’Montmorency College of Dentistry, Lahore, Pakistan, Qureshi Ahmad Shamim , Shaheen Asmi , Javed Hafiza Asma Javed , Qadir Samina , Hussain Shabbir , Sadiq Nauman
Published: April 2023

OBJECTIVE: The objectives of this study were to observe the changes in enzyme behavior during Orthodontic tooth movement and Rapid Maxillary expansion to predict the exact timing for commencement of treatment in young children. METHODOLOGY: We selected fifteen patients having age between 9-15 years. Periodontal protocols (Samples from buccal and palatal side) were observed and sample collection before initiation of treatment, during and after activation was done from patients requiring RME. The GCF and ALP activity was checked at the experimental location. RESULTS: The initial enzyme activity in GCF and ALP was calculated between the buccal and Control sites during maxillary expansion. It was observed that during activation of the appliance and then after 3 months of retention period a significantly elevated enzyme levels were still noted at the experimental sites. CONCLUSION: An Increase in osteoblastic activity during adolescence period can predict commencement of early or delayed intervention for most favorable treatment results.
Expectation and Satisfaction Level of Students with Impact of Formative Assessment on the Scores of Summative Assessments in the Subject of Dental Materials -A Study from Private Dental College Karachi Pakistan
Authors:   Ziauddin College of Dentistry, Fatima Nazish , Usmani Ambreen
Published: April 2023

OBJECTIVE: To evaluate the improvement in the scores of summative assessment after formative assessment practices as well as expectation and satisfaction level of students with formative assessment in subject of the science of Dental Materials. METHODOLOGY: It was a longitudinal study with pre-post design that was conducted on second-year BDS students over a year. Students were selected by non-probability, convenience sampling technique from a private dental college. Summative assessments conducted at the end of semester III were considered pre-intervention tests. Semester IV was planned with formative assessment and feedback sessions after every topic and summative assessments conducted at the end of semester IV were considered Post-intervention tests. The summative assessment was done by Multiple Choice questions and a structured practical exam. A structured close-ended questionnaire was administered to record Students' level of expectation and satisfaction. The analysis was performed by using SPSS version 20. Quantitative analysis was reported by means and standard deviation. Furthermore, paired sample t-test was performed to analyze students' scores before and after formative assessment. Frequencies and percentages were calculated for the number of responses to each item in the questionnaire. RESULTS: Performances of students in semester III (before formative assessment) with semester IV (after formative assessment) were compared with paired-sample t-test results showed a significant increase in the scores of students before (M=62.74, SD±14.72) to after (M=67.16, SD ±14.53). KEYWORDS: Expectation, satisfaction, formative assessment, Summative Assessment, Science of dental materials.
Top-Down Analysis of Supercharged Proteins Using Collision-, Electron-, and Photon-Based Activation Methods
Authors: Juetten Kyle , Brodbelt Jennifer
Published: April 2023

The impact of supercharging on the fragmentation patterns of six proteins, ubiquitin, cytochrome c, staph nuclease, myoglobin, dihydrofolate reductase, and carbonic anhydrase, was investigated for five activation methods, HCD, ETD, EThcD, 213 nm UVPD, and 193 nm UVPD. Changes in sequence coverage, alterations in the number and abundance of preferential cleavages (N-terminal to proline, C-terminal to aspartic or glutamic acid, adjacent to aromatic residues), and changes in individual fragment ion abundances were evaluated. Large decreases in sequence coverage were observed upon supercharging of proteins activated by HCD, whereas modest gains were observed for ETD. Minimal changes in sequence coverage were observed when using EThcD, 213 nm UVPD, and 193 nm UVPD, all which tended to display the highest sequence coverages of the activation methods. Specific preferential backbone cleavage sites were increasingly enhanced for all proteins in supercharged states for all activation methods, particularly for HCD, 213 nm UVPD and 193 nm UVPD. Even if large gains in sequence coverages were not apparent for the highest charge states, supercharging consistently led to at least a few new backbone cleavage sites for ETD, EThcD, 213 nm UVPD and 193 nm UVPD for all proteins.
Application of place and promotion marketing strategies to library and information services in public universities,in Anambra state, Nigeria
Authors: Odume  , Chinonso Stella
Published: April 2023

This study determined the application of place and promotion marketing strategies to library and information services in Nigerian public universities in Anambra State, Nigeria. Two research questions and two null hypotheses guided the study. Descriptive survey research design was adopted for the study. Seventy Nine librarians and library officers in public universities in Anambra State were studied without sampling. Structured questionnaire validated by three experts was used for data collection. The reliability of the instrument was done through trial testing and data analysis using Cronbach alpha yielded correlation coefficients of 0.78 and 0.82 for clusters B1 to B2 with an overall coefficient of 0.80. Mean, standard deviation and t-test were used for data analysis using Special Package for Social sciences (SPSS) version 23.0. Findings revealed that librarians and library officers agreed that they applied majority of the items listed on place and promotion marketing strategies to library and information services. However, they disagreed that most of the items on place as a marketing strategy are applied in this regard. Ownership of university did not significantly influence respondents’ mean ratings on application of place and promotion marketing strategies in library and information services. The researcher concluded that librarians and library officers do not adequately apply place and promotion marketing strategies to library and information services. It was recommended among others that; library management in public universities should expose librarians to marketing library services through capacity building programmes to up-date their skills in the application place and promotion marketing strategies to library and information services.
Post covid-19 management: The strategic role of enterprise digitalization
Authors: Ahlem Omri  , Fatma Chikhaoui
Published: April 2023

The ongoing pandemic of Covid-19 disturbed the social and economic life. This virus has accelerated the firm’s digitalization and has created a situation of uncertainty about risks, strategies and best practices. On the bright side,Covid-19 has forced enterprises to operate in swiftly ways which revealed the firm agility and the great ability to adopt digitalization and remote working. This article concentrates on how the Covid-19 pandemic has affected the functioning of companies and highlighted the critical role of digitalization. In doing so, this research paper address the current lack to integrate between strategic management, Covid-19 crisis and digital entrepreneurship.
Intra-manufacturing export performance among ecowas member state
Authors: Olure Bank Adeyinka  , Ayodeji Salihu  , John Aiyedogbon  , Gbadebo Salako
Published: April 2023

The study examined role economic integration and trade facilitation in promoting manufacturing export among ECOWAS member states The objectives of the study were achieved using descriptive, statistical and econometric analyses of annual data covering the period 2015 – 2020. The descriptive analysis helped in assessing the level of economic integration among ECOWAS member states. The econometric analyses were use examine the effect of economic integration on trade facilitation as well as the role of trade facilitation and economic integration in promoting manufacturing exports among ECOWAS member states. The findings reveal the level of trade facilitation in ECOWAS is below world average. That is ECOWAS member states has higher bureaucratic processes with greater costs of exporting/importing. Furthermore, results from econometric analyses reveal economic integration can significantly help in promoting manufacturing exports among ECOWAS member states. Again, economic integration and trade facilitation can significantly influence manufacturing exports across ECOWAS member states, while manufacturing production had direct and significant impact on manufacturing exports. Some policy recommendations that would help to facilitate trade flow to improve manufacturing exports across ECOWAS member states were recommended.
The rights to legal counsel in Ethiopia: Evidence obtained in absence of legal counsel
Authors: Lamessa Gudeta Guder
Published: April 2023

The Right to legal Counsel is a basic right of human rights as provided under different international, regional and National instruments as crucial elements of rights to fair trial. The presence of counsel serves multiple purposes, including the Redress of the power imbalance between the authorities and the detained (particularly in terms of knowledge of the law), deterrence of torture and other ill-treatment capacity to address arbitrary or improperly justified detention, and ability to provide an alternative record of interviews to ensure the integrity of any evidence gathered. In many Jurisdictions the confession obtained in absence of lawyers are inadmissible as criminal evidences.In Ethiopia, the Defendant/accused person to assist by legal counsel is a constitutional rights givens by our laws at National level and at different Regional state level. However practically what we have seen in area of our courts, police custody, prison the place where this right has been implemented is allegedly different from what is said by law. In some circumstance, even the law by itself seems to be incompatible with practical application of this right. Such disparity and gap of the law and the practice regarding this defendant right has great impact on the fair trial. The inadmissibility of evidence obtained in absence of legal counsel did not provided by Ethiopian laws. Even when the detained/arrested/ person can get the legal counsel ( at what time?) by itself is not clear.This in turn begs different question among legal professionals regarding the admissibility or inadmissibility of evidence obtained in absence of legal counsel. This article try to identify the position of our laws, consult different jurisprudences of the other model country and gives clue for the criminal lawyers and legal professionals as to the respection of the rights to legal counsel as basic fair trial. And inadmissibility of any evidence obtained in absence of legal counsel since it has irretrievable effects on the defense rights.
A short-term course of Ukrainian as a foreign language: tasks, approaches, implementation
Authors: Trostynska O. , Komarova V.
Published: April 2023

The article defines tasks and outlines approaches and ways to implement a short-term Ukrainian language course for foreign students of a preparatory department using a course developed by the teachers of the Language Training Department of International Education Institute for Study and Research of V.N. Karazin Kharkiv National University as an example.

After the adoption of English as a medium of instruction at Ukrainian higher institutions, those international students of preparatory departments who do not have the appropriate language level have to learn two languages, i.e. English as a medium of instruction, and Ukrainian as the host country’s state language, which is crucial for functioning in the social and cultural environment.

A limited amount of classroom time for learning Ukrainian makes it a challenge for teachers and methodologists. The core task is to develop a short-term course that would contain all the main structures of the Ukrainian language. In addition, there is an objective to build a communication competence sufficient to help the students adapt to a new social and cultural environment while studying in Ukraine. As a result, the students should master the Ukrainian language at the A2 level, which corresponds to the “basic user of the language”.

The article includes the initial language proficiency level requirements according to the Common European Framework of Reference for Languages as well as the standards of Ukrainian as a foreign language at the A2 level.

The authors also highlight how communicative methodology combines a structural approach and deductive, inductive, implicit, and interactive teaching methodologies. There is a conclusion on the relevance and advisability of such methodologies for the short-term Ukrainian language course for international students.

The paper contains an analysis of the structure and content of the textbook “Learning Ukrainian” by V. Komarova, T. Laguta, and I. Sukhova based on the developed course materials. The book stands out among the other textbooks of Ukrainian for international students due to its condensed form and scrupulous selection of educational content. Moreover, the textbook corresponds to the needs of future international students who will be getting higher education in English at higher education institutions in Ukraine by forming communicative competence in Ukrainian.

The authors examine the approaches and methods of teaching that correspond to the purpose and features of teaching a short-term course. The article showcases the communicative approach as the most widespread language educational method while studying any foreign language, and the Ukrainian language in particular.
Arácnidos del Huila: biodiversidad, investigación y conocimiento popular
Authors: Valenzuela-Rojas Juan Carlos , Polo-Aldana Mayra Cistina , Reyes-Henández Héctor Fernando
Published: April 2023

En este capítulo se definieron las líneas de investigación en las cuales actualmente se desarrolla la aracnología en el departamento del Huila. Por último, se realizaron cinco entrevistas a distintas personas que brindaron perspectivas diferentes con respecto al conocimiento de los arácnidos: dos campesinos, dos habitantes urbanos y una Autoridad Mayor del Cabildo Inga de San Agustín Huila (indígena).
Comunidad y biodiversidad: un estudio de caso
Authors: Betancourth Toro Jhony Sebastián , Leyton Trujillo Lina Marcela , Puentes Ninco Laura Soraya , Brand Prada Mijael
Published: April 2023

La biodiversidad cumple un papel fundamental en los ecosistemas, a esto se le conoce como servicios ecosistémicos y benefician o son aprovechados por los humanos, directa o indirectamente (Ministerio de Ambiente y Desarrollo Sostenible [MinAmbiente], 2012); estos se clasifican teniendo en cuenta su función ecológica y pueden ser de regulación, producción, de soporte o culturales (Millennium Ecosystem Assessment [MEA], 2005; Valencia et al., 2010). En la fauna tipo aves, los servicios son de comportamiento o regulación e incluyen el control de plagas, la polinización, la dispersión y el carroñerismo (Pacheco, 2013); en anfibios y reptiles sucede algo similar, pero debido a las creencias y el rechazo hacia estos grupos son menos percibidos, algunas de sus funciones son la regulación de patógenos y la indicación de contaminación (Valencia et al., 2010).
Flora del Parque Jardín Botánico de Neiva, Huila, Colombia
Authors: Paredes Navia Julián Guillermo , Rosero Toro Jeison Herley , Dueñas Gómez Hilda del Carmen
Published: April 2023

En un mundo globalizado como el que habitamos, las ciudades están teniendo un crecimiento, en muchos casos acelerado y desordenado, y los espacios verdes cada día son más limitados. Según la Organización de Naciones Unidas (ONU, 2021), desde el 2007, más de la mitad de la población humana (~3.500 millones de personas) vive en ciudades, y posiblemente la cifra se duplicará hacia el 2050; uno de los resultados de ello es la marginalidad, con el aumento de habitantes en barrios pobres, que además presentan infraestructuras y servicios públicos (como recolección de basuras, sistemas de acueducto,salud, vías públicas, etc.), inadecuados y sobrecargados, lo cual está empeorando la contaminación del medioambiente y el crecimiento urbano incontrolado, sin dejar de mencionar que también ha aumentado el hambre y las muertes por la falta de acceso a los alimentos, y que el aire que respiran los habitantes en las ciudades no cumple con las normas de seguridad establecidas por la Organización Mundial de la Salud (OMS), lo que provoca alrededor de 4.2 millones de muertes al año por contaminación atmosférica.
Poblaciones ex situ: herramientas claves para la conservación
Authors: Pinedo-Castro Myreya
Published: April 2023

El desconocimiento en cuanto a la diversidad de especies en Colombia sigue siendo amplio. A pesar de ello, el país ha sido catalogado como el segundo país más diverso del planeta después de Brasil (Rangel, 1995; Rangel, 2005; Tobasura, 2006; Fondo Mundial para la Naturaleza [WWF], 2018) y como el primer país con mayor biodiversidad por kilómetro cuadrado del planeta (Sistema de Información sobre Biodiversidad en Colombia [SiB Colombia], 2016), posición que se ha disputado con Costa Rica (Acuña, 2003). De 58.312 especies registradas (SiB, 2019), 1.302 se encuentran en algún grado de amenaza, de las cuales 380 corresponden a vertebrados (Ministerio de Ambiente y Desarrollo Sostenible [MinAmbiente], 2017), razón por la cual, instituciones gubernamentales, no gubernamentales y académicas realizan esfuerzos continuamente tanto para conocer como para conservar la biodiversidad.
Comunidades de aprendizaje que apropian conocimiento aplicando el enfoque STEM
Authors: Avella Bernal Leonor , Chaparro Guevara Alexandra , Linares Archila Andrés Felipe
Published: April 2023

Esta obra otorga un aporte para la apropiación de la ciencia, la tecnología e innovación desde las comunidades de aprendizaje como laboratorios vivos de generación y apropiación de conocimiento para la transformación de los territorios y su sostenibilidad, la interpretación crítica de las narrativas sobre el uso de la CTeI y aprendizajes adquiridos por las 194 comunidades de aprendizaje.
Adherence to guidelines on the use of amoxicillin for treatment of ambulatory pneumonia in children younger than 5 years, Colombia, 2017–2019
Authors: Moyano Ariza Luisa , Ochoa Brindis , Shewade Hemant D. , Edwards Jeffrey K. , Trujillo Trujillo Julián , Cuellar Claudia M. , Rodríguez Jaime , Hann Katrina , Sanchez Mauro
Published: April 2023

Objectives.

To determine the level of adherence to clinical guidelines in prescribing amoxicillin to children younger than 5 years with pneumonia in outpatient settings in Colombia from 2017 to 2019, and assess the factors associated with adherence

Methods.

This was a cross-sectional study of secondary data from the Colombian Integrated Social Protection Information System database. Adherence was defined as prescription of oral amoxicillin for bacterial and unspecified pneumonia and non-prescription for viral pneumonia. Variables examined included: age (< 1 year, 1–4 years) of child; sex; cause of pneumonia (bacterial, viral, unspecified); region (Andean, Amazonian, Pacific, Caribbean, Insular, Orinoquian); and payment mechanism (without prior authorization, capitation, direct payment, pay per case, pay for event).

Results.

Of 215 925 cases of community-acquired pneumonia reported during 2017–2019, 64.8% were from the Andean region, 73.9% were bacterial pneumonia and 1.8% were viral pneumonia. Adherence to guidelines was observed in 5.8% of cases: this was highest for children diagnosed with viral (86.0%) compared with bacterial (2.0%) pneumonia. For children diagnosed with bacterial pneumonia, 9.4% were prescribed any antibiotic. A greater proportion of children covered by capitated payments (22.3%) were given treatment consistent with the guidelines compared with payment for event (1.3%).

Conclusion.

In this first study from Colombia, adherence to guidelines for outpatient treatment of children with bacterial pneumonia was low and was better for viral pneumonia. Further qualitative studies are needed to explore the reasons for this lack of adherence and why bacterial pneumonia was the most commonly reported etiology.
Farklı Branşlarda Öğrenim Gören Öğretmen Adaylarının Coğrafya Okuryazarlık Düzeylerinin Belirlenmesi: Van Yüzüncü Yıl Üniversitesi Örneği (Determining the Geographical Literacy Level of Teacher Candidates Who Have Study in Different Branches: Van Yüzüncü Yıl University Example)
Authors: Çevik Özcan , Yılmaz Murat
Published: April 2023

Bu çalışmada farklı branşlarda öğrenim gören öğretmen adaylarının coğrafya okuryazarlık düzeyleri belirlenmiş ve bu düzeyin farklı değişkenlerle ilgisi incelenmiştir. Çalışmada problem durumunu belirlemek adına geçmişte veya halen olan bir durumu gerçekte var olduğu gibi inceleyen tarama modeli kullanılmıştır. Araştırmaya 2018-2019 Eğitim ve Öğretim yılında, Van Yüzüncü Yıl Üniversitesi Eğitim Fakültesi’nde 7 farklı branşta öğrenim gören 260 öğretmen adayı katılmıştır. Katılımcıların branşları Sosyal Bilgiler, Türkçe, Sınıf, Ortaöğretim Matematik, Tarih, Fen Bilgisi ve Türk Dili ve Edebiyatı öğretmenliğidir. Çalışmada verilerin analizinde ise betimsel analiz, ilişkisiz örneklemler için t-testi, Pearson Korelasyon analizi, tek yönlü ve çift yönlü varyans analizi (anova) kullanılmıştır. Çalışma sonucunda, öğretmen adaylarının coğrafya okuryazarlık seviyelerinin belirlenen yeterlilik ölçütünün altında kaldığı ve coğrafya okuryazarlıklarının düşük seviyede olduğu ortaya konulmuştur. Bunun yanında coğrafi bilgi ve beceriler açısından erkeklerin kadınlara göre daha yeterli olduğu, Sosyal Bilgiler ve Türkçe bölümünde öğrenim gören öğretmen adaylarının coğrafya okuryazarlık düzeylerinin Sınıf, Fen Bilgisi, Matematik ve Türk Dili ve Edebiyatı öğretmenliği bölümlerinde okuyan öğretmen adaylarından daha yüksek olduğu, coğrafi bilgi ve beceriler açısından sınıf değişkeninin bir etkisi olmadığı belirlenmiştir. Coğrafya okuryazarı olmada, mezun olunan okul türünün belirleyici bir etkisinin olmadığı; okuryazarlığın yaş değişkenine göre anlamlı bir farklılık gösterdiği, seyahat edilen il ve ülke sayısına göre anlamlı bir farklılık göstermediği belirlenmiştir. Coğrafi bilgi ve beceriler açısından coğrafya dersine yönelik olumlu tutum sergileyen öğretmen adaylarının olumsuz tutum sergileyenlere göre daha yeterli olduğu şeklinde birçok bulgu elde edilmiştir. Bu çalışma 2021 yılında Van Yüzüncü Yıl Üniversitesi Eğitim Bilimleri Enstitüsü’nde Doç. Dr. Murat Yılmaz’ın danışmanlığında Özcan Çevik tarafından hazırlanan ‘Farklı Branşlarda Öğrenim Gören Öğretmen Adaylarının Coğrafya Okuryazarlık Düzeylerinin Belirlenmesi’ adlı yüksek lisans tezinden üretilmiştir.
2023 McMaster Energy Week Nexus Case Competition: The Future of Fuel
Authors: Lai Puisand , Lek Mieke , Gurunathan Kavishalini , Carmona Tyler
Published: April 2023

The theme for the 2023 Energy Nexus Case Competition was “The Future of Fuel”. In 2022, gasoline prices reached record highs in Ontario. Canadians use fuel for transportation, electricity, heating, and cooking, among other things. Given the volatility of fuel and our great dependency on it, what are some steps we can take to aide our dependency on fuel? The following abstracts were selected as the top three finalists amongst the delegates chosen for the Energy Nexus Case Competition taking place during the 6th annual McMaster Energy Week. McMaster Energy Week is Canada's first student-led energy week that aims to take the complex and multi-faceted issue of climate change and present solutions towards building Canada's sustainable future. We are bringing together academia, industry, government, communities, and students to further the dialogue on Canadian environment and energy. For more information on this visit https://www.mcmasterenergyweek.com/ or email chair@mcmasterenergyweek.com.
Effect of Mitochondrial Function of Ovarian Granulosa Cells on In Vitro Fertilization and Embryo Transfer Outcomes in Obese Polycystic Ovary Syndrome Patients
Authors: Wang Jing , Gao Yana , Wu Hongli , Wang Gaijing , Cui Jie , Qin Jinjin , Wang Lulu , Zhao Yakun , Li Rui
Published: April 2023

Objective: To investigate the effect of abnormal ovarian granulosa cell metabolism on in vitro fertilization and embryo transfer (IVF-ET) outcomes in obese polycystic ovary syndrome (PCOS) patients. Methods: Patients with PCOS who met the study criteria were screened according to the inclusion criteria. A total of 32 patients with obese PCOS were recruited into the study group, and 39 patients with non-obese PCOS were recruited into the control group. The general data (age, body mass index, and years of infertility), insulin resistance index (HOMA-IR), follicle-stimulating hormone (FSH), luteinizing hormone (LH), granulosa cell mitochondrial function, and IVF-ET outcome of patients in the study group and control group were retrospectively analyzed. Results: The differences in age and years of infertility between the study group and the control group were insignificant (P > 0.05), and the body mass index (BMI) of the study group and control group was 30.5 ± 1.24 kg/m2 and 22.3 ± 1.12 kg/m2, respectively, in which the difference was statistically significant (P < 0.05); the HOMA-IR of the study group was significantly higher than that of the control group (P < 0.05); the reactive oxygen species (ROS) in the study group was significantly higher than that in the control group (P < 0.05), and the ATP content in the study group was significantly lower than that in the control group (P < 0.05); comparing the FSH and LH levels between the two groups, the difference was not statistically significant (P > 0.05); the rate of IVF-ET failure was significantly higher in the study group than in the control group. Conclusion: PCOS is a complex endocrine disorder, and obesity is one of the independent risk factors for the development of PCOS.
Epidemiological profile of COVID-19 patients undergoing invasive mechanical ventilation in a Brazilian public hospital: a comparison between 2020 and 2021
Authors: Oliveira Kelly Cristina da Silva , Limongi Vivian , Aily Jessica Bianca , Souza Júnior José Eustáquio de , Oioli Ana Paula Toma , Amaral Carolina de
Published: April 2023

Introduction: COVID-19 can lead to respiratory complications and require some patients to undergo invasive mechanical ventilation. As a recent disease, it is not clear which patient characteristics predispose to the need for the procedure. Aim: The aim of this study was to describe and compare the epidemiological profile of patients who required invasive mechanical ventilation between 2020 and 2021. Outlining: This is a descriptive and analytical study. Patient characteristics and outcomes were collected from medical records and divided into four groups (survivors - GS and non-survivors - GN of 2020 and 2021). Results: The sample consisted of 501 patients over 18 years of age. There was a difference (p<0.005) in Chronic Obstructive Pulmonary Disease, pneumothorax, age, prone position, and dialysissupport in the GN, and tracheostomy, longer hospital stays, and longer stay in the  Intensive Care Unit in the GS. The year 2020 had an older population with pneumothorax and neurological disease among non-survivors. Implications: The findings of the study will assist in the management of healthcare resources, implementation of measures to reduce the time of mechanical ventilation, and prioritization of vaccination for at-risk groups.
Penerapan Akluturasi Budaya pada Masjid Al-Imtizaj Bandung
Authors: Tyas Widji Indahing
Published: April 2023

Penerapan akulturasi tersebut dapat ditemukan pada perancangan bangunan Masjid Al – Imtizaj, yang merupakan salah satu masjid di kota Bandung, tepatnya terletak pada area gedung Abdurrahman bin Auf Trade Center. Bangunan ini memiliki konsep desain yang berbeda daripada desain bangunan masjid pada umumnya dan masyarakat sekitar sering menjuluki sebagai “Kelenteng Berkubah”. dimana pada perancangannya memiliki bentuk dan fasad yang unik dan berbeda juga memadukan antara konsep arsitektur Islam dan arsitektur Cina yang menjadi ciri khas tersendiri
Penilaian Sumber Dan Siklus Material Arsitektural Dalam GBCI Pada Gedung Kuliah Bersama Institut Pertanian Bogor (IPB)
Authors: Sulistiawan Agung Prabowo , Maryanto Dzaki Arif Maryanto Arif , Aprizal Muhammad Ilham , Rachman Fikry Fathur
Published: April 2023

AbstrakPermasalahan lingkungan dan krisis energi merupakan persoalan dunia dan isu utama yang dihadapi oleh manusia saat ini. Di beberapa negara maju dibidang industri konstruksi menghabiskan sekitar 30% energi yang berdampak negatif terhadap lingkungan sekitar. Untuk mengurangi konsumsi energi dalam bidang konstruksi maka bangunan hijau dinilai sebagai sebuah upaya untuk mereduksii dampak negatif pada lingkungan sekitar. Penelitian ini bertujuan mengidentifikasi serta menilai Gedung Kuliah Bersama Institut Pertanian Bogor berdasarkan dua kriteria, yaitu Sumber serta Siklus Material pada Greenship versi 1.2 GBCI atau Green Building Council Indonesia. Penelitian ini menerapkan metode kualitatif dengan menganalisis data hasil survey ke objek studi dengan beberapa sumber yang berkaitan. Studi literature dilakukan di awal untuk mencari teori dan literatur yang relevan dengan pembahasan prinsip bangunan hijau yang ramah terhadap lingkungan yang mendukung analisa dalam penelitian ini. Analisis mengacu pada enam kriteria Sumber dan Siklus Material berdasarkan ketentuan Greenship GBCI. Berdasarkan hasil analisa dapat disimpulkan bahwa Gedung Kuliah Bersama Institut Pertanian Bogor (IPB) masih belum memenuhi persyaratan Bangunan Hijau dengan total presentase sebesar 21,4% berdasarkan penilaian dua kriteria, yaitu: Sumber dan Siklus Material pada Greenship GBCI.Kata kunci: Bangunan hijau, Greenship,GBCI, Institut Pertanian Bogor (IPB) ABSTRACTEnvironmental problems and energy crises are world problems and the main issues faced by humans today. In some developed countries, the construction industry consumes about 30% of energy which has a negative impact on the surrounding environment.  To reduce energy consumption in the construction sector, green buildings are considered as an effort to reduce negative impacts on the surrounding environment.  The purpose of this research was to identify and assess the Gedung Kuliah Bersama Institut Pertanian Bogor based on the criteria of Source and Material Cycle in Greenship version 1.2 Green Building Council Indonesia (GBCI). This research applies a qualitative method by analyzing survey object’s data with several related sources. The literature study was carried out at the beginning to find theories and literature relevant to the discussion of the principles of green buildings that are friendly to the environment that support the analysis in this study. The analysis carried out refers to the six criteria of the Source and Material Cycle according to the Greenship GBCI. Based on the results of the analysis, it can be concluded that Gedung Kuliah Bersama the Bogor Agricultural University (IPB) still does not meet the Green Building requirements with a total percentage of 21.4% based on the assessment of two criteria, namely: Source and Cycle of Materials in the GBCI Greenship. Keywords: Green Building, Greenship, GBCI, Bogor Agricultural University (IPB)
Eksistensi Pola Geometrik, Organik, & Superimposisi Dalam Arsitektur Pada Kawasan Summarecon Bekasi
Authors: Bernadus Albert
Published: April 2023

Eksistensi sebuah pola dalam kota ataupun kawasan di dalam kota sangatlah penting dalam membantu pengaturan hubungan aktivitas, tata bangunan, jaringan jalan, ruang terbuka, dan sistem kota lainnya, pola tersebut akan ada yang muncul secara alami atau juga dengan disengaja dan diantaranya akan ada yang lebih dominan dibanding satu sama lainnya. Untuk bisa merencanakan sebuah sistem kawasan yang efektif maka haruslah diidentifikasikan terlebih dahulu pola dasar kawasan tersebut seperti padahalnya kawasan Summarecon Bekasi dimana akan ada pola dominan didalam kawasan tersebut yang bisa membantu dalam pertumbuhan kawasannya baik dari penambahan bangunan baru, pembaharuan jaringan jalan, dan lainnya. Hasil penelitian ini akan menunjukan ke eksistensian pola-pola di dalam kawasan Summarecon Bekasi baik yang alami dan yang disengaja dan pola mana saja yang lebih dominan dibanding dengan yang lainnya agar bisa menjadi acuan dalam pengambangan kawasan dimasa depan baik dari perkembangan fisik dan juga sosial.
Penerapan Arsitektur Hijau pada Perancangan Apartemen Mahasiswa di Medan
Authors: Rambe Yunita Syafitri
Published: April 2023

Layanan pendidikan di Indonesia semakin berkembang seiring berkembangnya arus globalisasi, teknologi dan informasi. Jumlah mahasiswa dari tahun ke tahun mengalami peningkatan, yang berasal dari dalam kota maupun yang berasal dari luar kota, mengakibatkan kebutuhan tempat tinggal sementara terus meningkat. Fenomena ini menjadi dasar berlomba-lomba untuk membangun hunian masyarakat salah satunya apartemen mahasiswa yang berada di Medan Sunggal. Pada apartemen ini, konsep bangunan menggunakan arsitektur hijau berlandaskan prinsip-prinsip arsitektur hijau dapat meminimalisirkan pengoperasian dan perawatan gedung apartemen ini sehingga akan berpengaruh pada biaya sewa yang akan di keluarkan mahasiswa agar tidak terlalu memberatkan. Penelitian  ini bertujuan untuk memberikan penilaian terhadap bangunan apartemen mahasiswa ini, apakah bangunan ini sudah memenuhi bangunan dengan penerapan arsitektur hijau. Metode penelitian berupa metode kualitatif deskriptif dengan melakukan pengumpulan data dan analisis terhadap hasil perancangan bangunan apartemen. Luaran dalam penelitian ini merupakan tercapainya tujuan penelitian dengan melakukan publikasi sebagai referensi untuk penelitian berikutnya.
Pola Dan Karakteristik Kualitas Spasial Ruang Pada Pantai Di Kecamatan Kuta, Bali.
Authors: Nurwarsih Ni Wayan
Published: April 2023

Pemanfaatan ruang pada Daya Tarik Kawasan Wisata Pantai di Kecamatan Kuta diasumsikan sebagai tuntutan dari kebutuhan ekonomi, sosial, budaya dan politik. Pariwisata selanjutnya dianggap telah mendefinisi ulang penggunaan ruang pada area wisata pantai di Bali. Ruang-ruang yang hadir tidak memiliki regulasi dan tidak terorganisir, sehingga menciptakan tata kelola dan memunculkan praktik konsumsi ruang yang mungkin terbentur oleh era digital saat ini. Kehadiran praktik konsumsi ruang ini menandakan adanya perbedaan antara konsep atas ruang yang dirancang sebelumnya, yang ternyata tidak sesuai representasi. Konsep dalam representasi ruang menyatakan bahwa ruang-ruang pada Daya Tarik Kawasan Wisata Pantai dibuat untuk memperlakukan semua pengguna sama, tidak menghadirkan fungsi lain, yaitu untuk kepentingan fungsi sosial dan budaya. Penelitian ini mengkaji bagaimana pola dan karakteristik kualitas spasial ruang secara sosial, sehingga persepsi dan kualitas terhadap efek kombinasi sifat-sifat yang tanggap terhadap kondisi budaya dan pengalaman serta ketertarikan pengguna didapatkan dan bagaimana gambaran perubahan fungsi dan kualitas toleransi kepada dampak kebutuhan ruang masyarakat lokal dan wisatawan, agar dapat mengetahui bentuk kualitas ruang secara arsitektur dalam bentuk diagram bentuk dan hakikatnya. Temuan pada akhirnya akan mengidentifikasi pola kualitas ruang secara arsitektur, sehingga masyarakat paham kombinasi ruang secara spasial dan lebih spesifik lagi pada ruang pantai di Daya Tarik Kawasan Wisata Pantai di Kecamatan Kuta.