bluuebunny/crossref_metadata_2025 huggingface dataset:
Beyond Extractive Methods – Navigating the landscape of Abstractive Summarization Methods
Authors:   Assistant Professor (IT), Department of Information Technology, Thakur College of Science and Commerce, Kandivali Mumbai, India., Kevin Sherilyn , Mishra Satish , Sharma Siddhi
Published: April 2024

Today, millions of data are generated every hour, which highlights the need for summarizing all this data accurately and efficiently. Doing such a task manually is tedious. This welcomes the need for automatic summarizing techniques. Generating precise and concise summaries of long text data is a necessity. Automatic summarization includes two primary techniques- Extractive and Abstractive Summarization. Extractive Summarization uses important sentences and keywords to construct the summary whereas abstractive summarization understands the text and generates a summary. The encoder-decoder architecture is generally used for abstractive summarization. This study briefs about various transformer architectures, including T5, BART, and Pegasus. Furthermore, a comparative analysis of these models on the same data is presented and the result of the same is compared on scores with the manually generated summaries- ROUGE1, ROUGE2, and ROUGEL. The purpose of this study is to understand the advancement of abstractive text summarization models as well as to understand the strategies and their usefulness.
Merging control-flow and dataflow architectures on a single chip
Authors: Korolija Nenad , Štrbac-Savić Svetlana
Published: April 2024

Computing power rises predominantly by increasing the number of cores in modern processors and the number of processors in cluster and cloud architectures. Along with increasing processing power, high-performance computing requirements also rise. The majority of the computing infrastructure includes control-flow processors that are based on the von Neumann paradigm. On the contrary, the principle of dataflow architectures is based on the data flowing through the already configured hardware. Recent research has proposed hybrid architectures, where both control-flow and dataflow hardware would exist on the same chip die. This article proposes a new hybrid control-flow and dataflow architecture where the control-flow hardware resembles modern graphical cards with thousands of cores and each GPU core has a reasonable amount of data-flow hardware. In this way, the advantages of dataflow architecture are exploited, including faster processing of high-performance computing algorithms and lower power consumption, while the conventional problem of communicating between control-flow and dataflow architectures is minimized. The proposed architecture is tested by analyzing the conjugate gradient method executed on both control-flow and dataflow hardware. The execution of the algorithm is divided onto GPU cores, and the execution of repeated instructions on each GPU core is delegated to the assigned dataflow hardware. The results indicate that it is possible to accelerate the execution of algorithms using the proposed architecture.
Research progress on ZnO/MoS2/rGO ternary photocatalysts
Authors: Zhang Runlin , Yang Weiwei , Chen Qiuyu , Du Zhengyan , Meng Zeshuo
Published: April 2024

Energy shortages and environmental pollution have become one of the important global issues, and semiconductor photocatalytic technology is considered one of the most effective means to solve these problems. As a new and efficient green material, ZnO has attracted wide attention. ZnO is widely used in the field of photocatalysis due to its non-toxicity, low cost, environmental friendliness, adjustable band gap, high electron density, and chemical stability. However, the recombination of photogenerated charge carriers in ZnO hinders its practical application and lowers the utilization efficiency of visible light. On the other hand, molybdenum disulfide/reduced graphene oxide (MoS2/rGO), as a binary non-precious metal co-catalyst, has a larger specific surface area, suitable band gap width, and visible light response capability compared to a single-phase graphene co-catalyst. Therefore, introducing the MoS2/rGO co-catalyst into the ZnO system can provide more active sites, reduce the probability of photogenerated charge carrier recombination, and improve the utilization efficiency of visible light. In this review, we summarize the hydrothermal synthesis methods for preparing this highly demanded nanocomposite material, including one-step and stepwise methods. Subsequently, we elaborate on the mechanism of enhancing light absorption and achieving efficient electron-hole separation behavior in the ternary system heterojunction structure during the photocatalytic process. Due to its significant advantages, this ternary system heterojunction structure has been widely applied in the field of photocatalysis, including applications such as pollutant degradation, sterilization, and water splitting.
Advanced Financial Management
Authors:   Associate Professor  Dr. Vishwanath Karad MIT World Peace University’s School of Business, Pune, Maharashtra, India., Sawalkar – Saxena Dr. Rohini , Rajput Prof. Vijaya Bhagavansingh ,   Assistant Professor in Finance  Sinhgad Business School Pune, Maharashtra, India., Kale Dr. Sonali Gopal ,   Associate Professor and HOD (Finance)  Aditya Institute of Management Studies and Research (AIMSR) Mumbai, Maharashtra, India., Huparikar – Shah Prof. Aditee ,   Assistant Professor  Indira College of Engineering & Management  Parandvadi, Maharashtra, India., Moholkar Mrs. Nilambari ,   Assistant Professor Dr. D. Y. Patil Institute of Technology Pimpri, Maharashtra, India
Published: April 2024

Financing is undoubtedly one of the most important prerequisites for beginning any kind of company. Furthermore, a sufficient corpus of assets and efficient financial management are required for the whole of a company’s life, even after it has been sold or wound up the business. As a result, the management of finances, management of rules in compliance with regulations, and monitoring of finances are all required at every step of the company lifecycle. those that have better financial management generally incur losses or make lower profits, while those that have weaker financial management typically enjoy exponential growth from their financial management. Advanced finance management courses that are specialised may be pursued in order to further enhance one’s competence and boost one’s chances of finding job in the financial business. The book titled “Advanced Financial Management” makes it possible for a business to make effective use of its resources, attain financial stability, and thrive in terms of development.
Rapid auxin signaling: An ancient and conserved response in plants
Authors: Zhou Yewei , Wang Chunyan , Yu Yongqiang , Ding Zhaojun , Xu Tongda
Published: April 2024

Rapid auxin responses in plants are crucial in initiating cellular changes. These responses are involved in processes such as plasma membrane depolarization, cytoplasmic streaming, apoplastic pH changes, calcium influx, etc. Recent studies illustrated how auxin triggers rapid changes in protein phosphorylation in different species through both the ABP-TMK auxin perception at the cell surface and a conserved RAF-like kinase-based mechanism. These works uncovered an ancient system for rapid responses to the auxin signaling molecule, shedding light on its profound impact on various cellular pathways and functions.
Advances of fluorescent DNA nanostructures in biomedical applications
Authors: Shen Xiaotong , Cao Mengyu , Xing Xiner , Ouyang Jin , Na Na
Published: April 2024

With the rapid development of DNA nanotechnology, the emergence of fluorescent DNA nanostructures (FDNs) has enlarged the biological applications. FDNs have great advantages of precise localization and real-time tracing in bioimaging. In this review, the recent biomedical developments of FDNs have been reviewed, including the design of FDNs, and the corresponding applications on biomarker sensing, bioimaging, cancer diagnosis and therapy. Firstly, the development of DNA nanostructures and the corresponding DNA-based nanomaterials were briefly introduced. Simultaneously, to make a better demonstration, the background and theory of the fluorescence detections were briefly introduced. Thereafter, the synthetic strategies of DNA nanostructure were summarized and classified, which facilitated the multiple functionalizations for sensing and bioimaging. Subsequently, the biomedical applications of FDNs are comprehensively summarized based on different detection strategies, including fluorescence resonance energy transfer (FRET), nucleic acid amplification (NAT), aggregation-induced emission (AIE), near-infrared (NIR)-photoactivation, small fluorescent dyes loading, and surface plasmon resonance (SPR) technologies. Finally, an insight into the challenges and future perspectives is provided. As reviewed, FDNs are important tools in precision medicine, showing great potential in both in vivo and in vitro cancer diagnosis and treatments. Undoubtedly, FDN-based technology is a promising strategy for constructing versatile nanodevices in biological applications and will excel in human healthcare.
Improving prediction of treatment response and prognosis in colorectal cancer with AI-based medical image analysis
Authors: Liu Xiangyu , Zhang Song , Shao Lizhi , Sun Caixia , Li Bao , Wei Wei , Ying Zuobin , Liu Zhenyu , Tian Jie
Published: April 2024

The heterogeneous response and prognosis of patients with colorectal cancer (CRC) to standard treatment regimens remains a challenge for clinical management. Individually weak prognostic markers, defined by gene mutations and protein expression, are difficult to apply in routine clinical practice because of their high acquisition cost and mediocre prediction accuracy. Visual evaluation of medical images, including radiology and digital pathology images, is an important part of CRC management. With the rapid development of artificial intelligence (AI), high-dimensional imaging features other than visual information are increasingly being used to develop imaging markers. At different stages of treatment, accurate predictions of treatment response and prognosis may help in selecting patients and tailoring their treatment. Here, we review the current state of AI applied to the medical imaging of CRC and describe its recent progress in short-term response and long-term survival prediction. In addition, we illustrate how these AI-based approaches may affect clinical decision-making. Although few approaches have been applied in routine clinical practice, their results are promising. Finally, we discuss the challenges in applying AI in clinical practice and possible future solutions from three perspectives: model interpretability, model generalizability, and patient privacy protection. This comprehensive assessment underscores the transformative potential of AI in CRC management and emphasizes the need for further exploration and integration into routine clinical workflows.
Flora, mycota and vegetation of Kupena Reserve (Rodopi mountains, Bulgaria
Authors:   Department of Plant and Fungal Diversity and Resources, Institute of Biodiversity and Ecosystem Research, Bulgarian Academy of Sciences, 23 Acad. G. Bonchev Str., BG-1113 Sofia, Bulgaria, Velev Nikolay , Ganeva Anna ,   Department of Plant and Fungal Diversity and Resources, Institute of Biodiversity and Ecosystem Research, Bulgarian Academy of Sciences, 23 Acad. G. Bonchev Str., BG-1113 Sofia, Bulgaria, Gyosheva Melania ,   Department of Plant and Fungal Diversity and Resources, Institute of Biodiversity and Ecosystem Research, Bulgarian Academy of Sciences, 23 Acad. G. Bonchev Str., BG-1113 Sofia, Bulgaria, Sopotlieva Desislava ,   Department of Plant and Fungal Diversity and Resources, Institute of Biodiversity and Ecosystem Research, Bulgarian Academy of Sciences, 23 Acad. G. Bonchev Str., BG-1113 Sofia, Bulgaria, Terziyska Tsvetelina ,   Department of Plant and Fungal Diversity and Resources, Institute of Biodiversity and Ecosystem Research, Bulgarian Academy of Sciences, 23 Acad. G. Bonchev Str., BG-1113 Sofia, Bulgaria, Apostolova Iva ,   Department of Plant and Fungal Diversity and Resources, Institute of Biodiversity and Ecosystem Research, Bulgarian Academy of Sciences, 23 Acad. G. Bonchev Str., BG-1113 Sofia, Bulgaria
Published: April 2024

The paper represents results from recent complex studies of flora, mycota and vegetation within the Kupena Reserve (Rodopi Mts, Bulgaria). Twenty six species, referred to 2 divisions, 4 classes and 17 families are recorded for the bryoflora. The vascular flora is presented by 370 species from 57 families, 122 of which are considered as medicinal plants. Eighty seven species of larger ascomycetes and basidiomycetes are found and reported for first time in the reserve. Four of them are of a high conservation value. The vegetation cover is consisted of mixed and monodominant deciduous and coniferous forests, as well as of mire, riverbank and mesic grasslands. Thirteen types of habitats according to the Habitats Directive classification have been recorded within the reserve.
Coastal zones – vulnerable biodiversity repositories: topics and contributions of the First European Symposium Research, conservation and management of the biodiversity of European seashores/RCMBES
Authors:   Department of Plant and Fungal Diversity and Resources, Institute of Biodiversity and Ecosys- tem Research, Bulgarian Academy of Sciences, 23 Acad. G. Bonchev Str., 1113 Sofia, Bulgara, Peev Dimitar
Published: April 2024

This paper aims to summarize the work, topics and contributions of the First European Symposium Research, conservation and management of biodiversity of European seashores/RCMBES, 8-12 May 2017, Primorsko, Bulgaria. The symposium was organized by OPIMOS and ECOPAN in cooperation with the Bulgarian Academy of Sciences, Faculty of Biology of Sofia University “St. Kliment Ohridski” and Primorsko Club Ltd. The symposium aimed to: 1) Present the status of scientific approaches within the European coastal areas; 2) Discuss the role of biodiversity research in trans-border issues; 3) Bring together scientists, academics, practitioners with a view to strengthening and promoting the trans-border cooperation and this with municipalities; 4) Define the priorities concerning various aspects of conservation research and good practices. In accordance, thirteen more detailed symposium topics were announced and later on discussed at the scientific sessions, during the field trip along the southern Bulgarian Black Sea coast and Strandzha Mt, and at the Symposium Round Table. In total, 65 scientific reports (5 plenary lectures, 26 oral presentations and 34 posters), prepared by 146 contributors from 11 countries were presented. The main topics of the contributions and studied regions, described briefly in the paper, helped to outline different problems related to the studies and conservation of the coastal areas, to share some good practices and new methodological approaches, as well as to define priorities and discuss the future design of studies and activities in these exceptionally rich in biodiversity, but also severely threatened areas.
Aethionema arabicum Andrz. ex DC (Cruciferae) in Bulgaria - in situ and ex situ conservation
Authors:   Institute of Biodiversity and Ecosystem Research, Bulgarian Academy of Sciences, 23 Acad. G. Bonchev Str., 1113 Sofia, Bulgaria, Delcheva Malina , Bancheva Svetlana ,   Institute of Biodiversity and Ecosystem Research, Bulgarian Academy of Sciences, 23 Acad. G. Bonchev Str., 1113 Sofia, Bulgaria
Published: April 2024

Aethionema arabicum Andrz. ex DC is extremely rare species of the Bulgarian flora. It is included in the Biological Diversity Act of Bulgaria and in the Red Book of Bulgaria with category Critically Endangered. The species is distributed in Balkan Peninsula (Bulgaria and Turkey), Southwest Asia (Asia Minor, Syria, Northern Iran) and the Caucasus. The only population of A. arabicum known in Bulgaria is situated in Eastern Stara planina floristic region, near Sotirya village, Sliven district. The population consists of only a few dozen individuals. This study provides information on the biology and ecology of the species, its population structure and the measures taken to increase the population. Protected area was designated to preserve this species.
Cyanoprokatyote and algal biodiversity in the tropical Lake Edward (Africa) with notes on new, rare and potentially harmful species.
Authors:   Department of Botany, Faculty of Biology, Sofia University 'St Kliment Ohridski', 8 Dragan Tsankov Blvd., 1164 Sofia, Bulgaria, Stoyneva-Gärtner Maya , Descy Jean-Pierre ,   Université de Liège, Unité d’Océanographie Chimique, Sart Tilman, B-4000, Liège, Belgium
Published: April 2024

The paper presents data on the biodiversity of prokaryotic and eukaryotic algae in the tropical Lake Edward, compiled from publications of the Damas mission (1935-1936), Hecky & Kling (1987) and our own results from a recent investigation of the lake phytoplankton in a three-year period (2016-2018) in the frame of the HIPE (Human impacts on ecosystem health and resources of Lake Edward) project (http://www.co2.ulg.ac.be/hipe). The provided checklist is based on modern algal taxonomy with relevant synonymizing of lists of previous authors. In total, 577 taxa from seven divisions were registered in the lake waters and in the Kazinga Channel. The richest division was Ochrophyta (287 taxa, 274 of which from Bacillariophyceae), followed by Chlorophyta (131 taxa), Cyanoprokaryota (134), Streptophyta (14), Euglenophyta (8), Pyrrhophyta (5) and Cryptophyta (1). 52 species (or only 1% of the taxa found) persisted in the lake since 30s of the 20th century till nowadays. More than half of the cyanoprokaryotes (65) are potentially toxic and harmful species. The checklist contains also data on algal abundance and frequency of occurrence, originally provided by the authors. In the phytoplankton samples, collected during the three cruises of the HIPE project, 248 taxa were found, among which the richest division was Cyanoprokaryota (104). From this total of 248 taxa, only 3 were frequent and 199 were very rare (from 1-3 samples) with 121 taxa found in one sample only. During 2016-2018, the most abundant species in the lake phytoplankton belonged to Cyanoprokaryota, Bacillariophyceae and Chlorophyta. The algae found in the lake have different ecological requirements and besides clear tropical species and some cosmopolites, some “cold water species” from northern and temperate regions were found. For them, as well as for some thermophilic species, considered alien for the lake, transport through different vectors was supposed. In the literature analyzed, 36 new taxa were described. Among them 26 taxa had Lake Edward as a single locality, and 10 were found also in other lakes and adjacent water bodies. Twelve of these new taxa were checked by modern taxonomists, but 24 still need taxonomic reconsideration.
Flora and vegetation of forest natural habitats in Natura 2000 protected area Kamchia (BG0000116)
Authors:   Faculty of Forestry, University of Forestry, 10 Kliment Ohridski Blvd., 1797 Sofia, Bulgaria, Tashev Alexander , Vitkova Antonina ,   Institute of Biodiversity and Ecosystem Research, Bulgarian Academy of Sciences, 2 Gagarin Str., 1113 Sofia, Bulgaria, Alexandrova Alexandra ,   Institute of Biodiversity and Ecosystem Research, Bulgarian Academy of Sciences, 2 Gagarin Str., 1113 Sofia, Bulgaria
Published: April 2024

The flora and vegetation in the protected area Kamchia were studied, as part of the European ecological network Natura 2000 within the implementation of the project Mapping and determination of the environmental status of natural habitats and species – phase I. Contract Nr. 04-014/05.04.2011. The paper presents data on the flora and vegetation in five types of forest natural habitats with codes 91E0, 91F0, 91G0, 91M0 and 92A0. Totally 222 high plant species were recorded in the studied habitats and seven of them were with conservation status. All obtained data confirmed the high conservation value of the flora and vegetation of the protected area and need for strict measures for its protection.
Flora, vegetation and habitats of Kayluka Protected Area.
Authors:   Department of Ecology and Environmental Protection, Sofia University ", Tzonev Rossen ,   St. Kliment Ohridski",   , Faculty of Biology, 8 Dragan Tsankov Blvd., Sofia 1164, Bulgaria, Baleva Rumyanka ,   Nature Section, Regional Historical Museum - Pleven, Stoyan Zaimov 3 Str., Pleven 5800, Bulgaria, Purvanov Ivan ,   Nature Section, Regional Historical Museum - Pleven, Stoyan Zaimov 3 Str., Pleven 5800, Bulgaria
Published: April 2024

The paper presents results from a study of the flora, vegetation and habitats of Kayluka Protected Area (Pleven District, Danube Plain, Bulgaria). It is one of the first protected areas in Bulgaria, with high regional and national significance. The vascular flora is presented by 844 species and subspecies from 99 families. The vegetation cover consists of various communities, but is mostly related to the deciduous forests and calcareous rocky terrains. The ruderalisation is also high because of the transformation of the biggest part of this area into recreational urban territory. Eleven habitat types (from totally 22 types), according to the Annex I of Habitats Directive, were recorded in the protected area, which is a part of the Natura 2000 site Studenets.
Macro- and micropalaeobotanical evidences for late Middle Miocene climate change in Bulgaria
Authors:   Department of Plant and Fungal Diversity and Resources, Institute of Biodiversity and Ecosystem Research, Bulgarian Academy of Sciences, 23 Acad. G. Bonchev Str., BG-1113 Sofia, Bulgaria, Ivanov Dimiter
Published: April 2024

An analysis of selected macrofloras (leaves, fruits and seeds) from NW Bulgaria using the Coexistence аpproach method was applied to obtain quantitative data about Volhynian and Bessarabian climate in studied area. The aim of the study is to compare the climate data derived from the analysis of macrofloras and palynological data. The Middle Miocene was a period of a subtropical/warm temperate humid climate with mean annual temperature between 16 and 18 °C and mean annual precipitation between 1,100 and 1,300 mm. Comparison of all data, received from different floras we can observed, showed that nevertheless some differences, in all cases there was a good relation between climate and vegetation dynamics. We observed some deviations in quantities, but they varied in small limits. The climate data derived from macro- and microfloras coincided well in regard to all parameters, nevertheless that different taxa determined coexistence intervals. In some cases, the macropalaeobotanical data provide narrow climate interval, that is explained by better taxonomic resolution and better identification of nearest living relatives (NLRs). The application of both methods has the advantage of obtaining both more accurate climate data and tracking climate change in more detail throughout the study period.
Fascination of Plants Day (FoPD) – reality and tradition in Bulgaria
Authors:   Department of Plant Physiology, Faculty of Biology, Sofia University “St. Kliment Ohridski”, 8 Dragan Tsankov blvd., 1164 Sofia, Bulgaria, Zhiponova Miroslava , Yotovska Kameliya ,   Department of Biology Education, Faculty of Biology, Sofia University “St. Kliment Ohridski”, 8 Dragan Tsankov blvd., 1164 Sofia, Bulgaria, Iantcheva Anelia ,   Agrobioinstitute, Agricultural Academy, 8 Dragan Tsankov blvd., 1164 Sofia, Bulgaria
Published: April 2024

The present report aimed at providing information about the Fascination of Plants Day (FoPD) which is an initiative for popularization of plant science. FoPD was launched by the European Plant Science Organisation /EPSO/ to facilitate the understanding of plant science and to improve its impact and visibility. The FoPD initiative was set worldwide in 2012 for first time, as Bulgaria joined in 2015 and since then participates with events that bring plant science to the non- scientific public. The Agrobioinstitute of the Agricultural Academy as a coordinator for Bulgaria took the challenge to introduce FoPD among the academic society. In response, the scientific faculties of Sofia University, Shumen University, Agricultural University and other plant research institutions embraced the opportunity to reveal the charm of plants. Here is given an overview of the generally mastered strategies as we put accent on the activities undertaken in the Faculty of Biology of Sofia University where faculty members and students united with the Agrobioinstitute. Our mission is on one hand to convince more Bulgarian researchers to participate in the coming FoPDs, and on the other hand to attract more schoolteachers to bring pupils and future scientists to the organized events, as well as interested citizens, professionals, decision-makers and media.
Phytoplankton of the reservoir “Dospat” (Rodopi Mts, Bulgaria) as indicator of negative trend in reservoir development due to long-term cage fish farming
Authors:   Institute of Fisheries and Aquaculture, 248 Vasil Levski, Str., Plovdiv – 4000, Bulgaria, Dochin Kostadin , Stoyneva Maya ,   Department of Botany, Faculty of Biology, Sofia University “St. Kliment Ohridski”, 8 Dragan Tsankov blvd., 1164 Sofia, Bulgaria
Published: April 2024

The paper presents the results of the recent (2011) investigation of phytoplankton composition and abundance, with its seasonal and spatial dynamics in the reservoir “Dospat” (the first in Bulgaria used for cage fish farming) and shows the changes in its waters after 30 years of exploitation. Totally 55 taxa from 7 divisions have been identified: Cyanoprokaryota (8), Pyrrhophyta (3), Euglenophyta (4), Cryptophyta (1). Ochrophyta (Bacillariophyceae – 26; Synurophyceae – 2), Chlorophyta (9) and Streptophyta (2), Cyanoprokaryotes have been recorded for first time in the reservoir and their harmful species Planktothrix rubescens and Aphanziomenon flos-aquae were found among the dominants and subdominants. The highest number of species was detected in June (42), the phytoplankton communities near to the dam were more species-rich and with higher abundance in comparison with those in the tailwaters, most probably due to the effect of the fish cages situated in the uppermost part of the reservoir.
New localities of Battarrea phalloides (Basidiomycota) in Bulgaria
Authors:   Department of Botany, Faculty of Biology, Sofia University 'St Kliment Ohridski', 8 Dragan Tsankov Blvd., 1164 Sofia, Bulgaria, Uzunov Blagoy
Published: April 2024

Battarrea phalloides, a rarely found basidiomycete which is included in the Red List of fungi in Bulgaria and also in the Red Data Book of the Republic of Bulgaria with threat status EN B2a(i,ii,iv), has been recorded in two new localities in Eastern Bulgaria near to the Black Sea coastal region. The paper provides data on macro- and microscopic description of the basidiomata, coordinates, and map of distribution of the fungus in Bulgaria.
Leveraging On Corporate Governance For Supply Chain Resilience Of Sugar Manufacturing Firms In Kenya
Authors: Oloo Antony Okoth , Ochieng’ Evans Bob
Published: April 2024

Sugar manufacturing firms in Kenya have faced a myriad of challenges with regard to cost control, production inefficiencies, incompetent management and lack of information technology integration in production issues which are directly controlled by management.  The influence of corporate governance on supply chain resilience of sugar manufacturing firms in Kenya thus cannot be underrated.  The specific objective of the study was; to assess the effect of Corporate Governance on Supply chain Resilience of Sugar Manufacturing firms in Kenya. The research study methodology followed a descriptive approach with a target population of the study of 240 respondents, covering various departments within the Sugar firms. A census survey was conducted on all the 15 registered sugar manufacturing firms in Kenya. Data collected was analyzed by both descriptive and inferential statistics using statistical package for social sciences (SPSS Version 28). Descriptive statistics involved calculation of means, frequencies, percentages and standard deviation. Inferential statistics on the other hand included the use of Pearson correlation coefficient to determine the extent of relationship among the independent study variables, while multiple regression analysis was used to establish the relationship between corporate governance and supply chain resilience. Findings from data analysis in the study indicated that corporate governance was significantly responsible for the supply chain resilience of sugar manufacturing firms in Kenya. Consequently, yielding a positive relationship in the regression model. The findings from the regression model indicated that corporate governance, significantly and positively affected supply chain resilience of sugar manufacturing firms in Kenya. The study therefore recommended that the management of sugar manufacturing firms in Kenya in collaboration with the appointing authorities should embrace good practices when appointing managing directors in-charge of the sugar firms to achieve supply chain resilience through, continuous production, resource optimization, quality output and general bottom line improvement.
Complex overlapping pedestrian target detection network based on the yolov3 model
Authors: Zhang Yuchi
Published: April 2024

This paper proposes a complex overlapping pedestrian target detection model based on yolov3 model by multi-scale feature fusion and context-aware mechanism. The SONY A7R3a camera shot the model on campus, and the data set was obtained after editing and collating. There were 358 high-definition videos with a resolution of 1920*1080, and the frame rate was 50HZ, about 179,000 frames. Through testing, this paper finds that compared with Single Shot Multibox Detector (SSD), the detection accuracy of the newly proposed model is slightly improved, the detection accuracy is the same as that of Faster R-CNN, and the detection accuracy of the newly proposed model is slightly worse than that of RetinaNet. However, the detection speed of Yolov3 is more than twice that of Single Shot Multibox Detector, RetinaNet and Faster R-CNN. The input size of Yolov3 is 320*320, and the processing of a single image only needs 22ms, so the detection speed of the simplified Yolov3 tiny is faster.
La Justice Écologique
Authors: Talbot Geneviève , Fliaguine Olga , Caouette Dominique
Published: April 2024

Éditorial
Development of the Potential of Tourism Villages in Increasing Community Employment from an Islamic Economic Perspective
Authors: Rahayu Riska Aditiya , Abizar  , Mawardi
Published: April 2024

Sumber Agung Village Tourism in Bandar Lampung City is a small example of the many efforts to develop the creative economy carried out by the community. The aim of this research is to determine the potential development of tourist villages in increasing community employment according to Islamic economic views. The research method is field research. Data collection techniques are carried out through Interview, Observation and Documentation methods. The research results show that management of this tourist attraction is community-based, but that does not mean without supervision from the manager. Management here uses the POAC principle (Planning, Organizing, Actuating and Controlling). The economic activities carried out by the community due to tourism are in accordance with Islamic economics.
Consideraciones sobre las prácticas de la evaluación formativa en la educación primaria. Un estudio de caso
Authors: Ortega Martínez Silvia Berenice , Cáceres Mesa Maritza Librada , Moreno Tapia Javier , Chong Barreiro María Cruz , García Robelo Octaviano
Published: April 2024

A challenge that has been present in Basic Education, through the years until now, has been how to apply the evaluation of learning, with emphasis on the training dimension, due to the little understanding and limitations around training teacher on these topics. The importance of promoting a culture of evaluation that ensures the development of a systematic, rigorous, reflective and academic decision-making process is emphasized. The study was developed at the “David Livingstone Elementary School, whose objective was to analyze how formative assessment practices are carried out in fifth and sixth grade students; Delimited in two moments, the first considers the theoretical foundations that support the understanding of the concept of evaluation, its different functions and strategies. In the second, the design and application of instruments for the collection and interpretation of the results is based, in correspondence with the questions formulated; which favor decision-making aimed at improvement. The conclusions indicate the importance of systematizing educational practices where feedback processes are privileged, through which self-regulation of learning is promoted, as part of the culture of evaluation.
Estudio optométrico en la población de Achupallas, provincia del Chimborazo
Authors: Rodríguez Paz Beatriz , Rocha Machin Aymee , Encalada Román Pablo Javier , Fernández Ortega Jessica Cecilia
Published: April 2024

Optometry as a science and part of health is on track to fulfill several very important roles, such as primary care for visual health. The visual anomalies present in people are the purpose of study so that the professional can give the pertinent solutions. Three very important phases that the examiner will take into account when evaluating; these are, the anamnesis, subjective examination, objective examination. It must be taken into account that the demography of a place can be an important factor for an alteration at the ocular level to appear, in addition to the daily habits of the inhabitants. The population of the present study belongs to the Province of Chimborazo, which is a rural area that does not have the same living conditions, which allows the study objectives to be very relevant to know the types of disturbances present in this sector. The results show varied alterations both in the anatomy and in the visual system of the population. To carry out this systematization, the type of research that was carried out was exploratory, which allows analyzing specific aspects of reality that have not been studied in depth.
Evaluación de atrayentes alimenticios y trampas para la captura de moscas de la fruta (Diptera: Tephritidae) en naranja (Citrus sinensis (L.) Osbeck) en Tepalcingo, Morelos, México
Authors: Hernández López Rosmery , López Martínez Víctor , Juárez López Porfirio , Alia Tejacal Irán , Guillén Sánchez Dagoberto , Hernández Pérez Ricardo
Published: April 2024

The study aim was to determine the most suitable trap-attractant combination for monitoring of Anastrepha complex in this fruit tree. The trial was carried out in a commercial orange orchard, variety "Valencia" variety, in Morelos state, during two periods (October-November / 2020 and (January-February / 2021), a total 12 weeks. Eight treatments were used, with two combinations (traps-attractants), plus two controls. The number of adults captured and the proportion by sex of females: males / treatments and the species present were analyzed. As results, three species of Anastrepha were identified: A. ludens, A. obliqua, A. striata, reporting as more abundant to A. ludens. Females had a higher prevalence than males, being A. ludens, that showed the highest proportion, (3:1) and (1.8:1) in both periods. While, in A. obliqua, it was the reverse (1:2) in first period and (0,69:1) in second period. The best trap-attractant combination corresponded to (PET-Cera Trap®) and (Multilure®-Cera Trap®) treatment, which reached the highest number of trapped flies and highest index (MTD), with 0,2292 and 0,2024 respectively. The climatic variables analyzed, mean temperature had a positive correlation on the insect species in both periods, with a greater influence on A. ludens, which showed better adaptation to the local conditions in orange crop.
Las tutorías de acompañamiento durante el período de excepcionalidad: resultados en la carrera de Educación Inicial de la UMET
Authors: García Álvarez Ignacio , Bernal Cerza Raisa Emilia , Arteaga Delgado Ramón , Macías Merizalde Azucena Monserrate
Published: April 2024

In the present work, elements of extraordinary importance are addressed regarding the accompaniment tutorials at the Metropolitan University of Ecuador under exceptional conditions. A pedagogical model of this activity is provided. The objective of this work is to propose a pedagogical model of the work of the accompaniment tutor in the current university, based on the experiences of the work of the tutors in the conditions of virtuality in the Initial Education career.
FUTURE PROSPECTS OF BIOMATERIALS IN NANOMEDICINE
Authors:   Department of Biophysics and Biochemistry, Baku State University, Baku, Azerbaijan, Khalilov Rovshan Khalilov
Published: April 2024

Biomaterials are materials that temporarily or permanently replace injured/lost tissue/organ functions for any reason, are used directly or are included in systems developed for this purpose. It is divided into two: natural and synthetic. Biomaterials have chemical, physical, mechanical, etc. properties to compensate for the said loss. It must have certain properties and be biocompatible. Non-biocompatible materials can have many significant negative effects on the body; for example, they can range from mild to severe, cause irritation, be allergenic or toxic and even create very tragic situations, leading to tumor formation. Biomaterials are often used temporarily for soft and hard tissue injuries/losses. Our body has the knowledge and ability to repair itself; soft tissue can usually regenerate within a few weeks, while hard tissue can regenerate within a few months or even a year. During this period, it is necessary to protect and support the injured tissue to ensure healthy regeneration (“healing”). Biomaterials are used for this purpose.
Effect of nano zinc oxide on the chlorophyll content of bean plants under drought stress
Authors:   Department of Biology, Baku State University, Baku, Azerbaijan, Babanli Safiyakhanim
Published: April 2024

The mechanism by which nanoparticles are involved in drought tolerance responses in plants is complex and requires further investigation. Considering the important role of ZnO nanoparticles in plant defense systems, it is relevant to investigate the effects of these nanoparticles depending on the type of plants and their developmental stages. The results of our experiments have shown that ZnO nanoparticles can play a role in the drought resistance of bean plants. It is clear from the results that ZnO nanoparticles, when applied under normal irrigation conditions, have a positive effect on the height development of plants, reduce the vegetation period and keep the pigment content stable. The difference in the pigment content observed in our experiments during the growing season may be related to the formation of bean leaves in different layers at different times. It is interesting that in the plants subjected to drought stress (variant IV) where ZnO nanoparticles were applied, the pigment content remains stable, although the growth of the plants is not fast. , the growing season is shortened and pod formation occurs more quickly. In addition, Chl pigment degradation does not occur for a long time, the leaves retain their greenness.
Indolent triple negative breast cancer
Authors: Natalenko S. A. , Vakhitova A. A. , Natalenko K. E. , Orlova R. V.
Published: April 2024

Triple-negative breast cancer (TNBC), while not the most frequent subtype, has a surprisingly aggressive course and low sensitivity to current antitumour drugs. Detection of predictive BRCA-mutation and administration of targeted therapy in the first lines of treatment of metastatic TNRML can significantly affect the life expectancy of patients. The clinical case of patient O. with BRCA-associated bilateral metachronous metastatic breast cancer demonstrates how important it is to implement a personalised approach in time. During the patient’s treatment, it was important to constantly compare the initial morphological profile of the tumour and the clinical course of the disease in order to suspect a discrepancy and to revise the surgical material. The administration of systemic drug therapy, taking into account the genetic and immunohistochemical features of the tumour, made it possible to achieve prolonged recurrence-free periods in two consecutive lines of treatment with preservation of the patient’s decent quality of life.
ALK-mutated thyroid cancer
Authors: Orlova R.  V. , Androsova A. V. , Belyak N. P. , Kutukova S. I.
Published: April 2024

At the moment, the standard of treatment in the Russian Federation for late stages of well-differentiated thyroid cancer (hereinafter referred to as WDTC) with a recorded radioiodine-resistant tumor status is the sequential administration of multikinase inhibitors: Sorafenib, Lenvatinib. Treatment protocols for subsequent lines have not been developed. The purpose of this article is to review the main molecular genetic features of WDTC and present the clinical observation of a patient with metastatic radioiodine-resistant follicular varient of papillary thyroid cancer (hereinafter referred to as PTC), which has progressed after previous lines of therapy. The patient’s tumor biological material was submitted for next-generation sequencing (NGS), which allows detection of all classes of molecular changes for a large number of genes. Due to the discovery of an ALK mutation and the lack of registered standards for subsequent treatment, ALK inhibitors were prescribed. This attempt to individualize therapy was successful: a partial response was registered during therapy and a significant clinical improvement in the patient’s general condition was noted. Therapy with ALK inhibitors continues to this day (46 months as of October 2023) and has a favorable toxicity profile. Thus, we can conclude that when the basic standards for the treatment of metastatic well-differentiated thyroid cancer have been exhausted, there is an individual selection of targeted therapy depending on the molecular genetic characteristics of the tumor process.
Ovarian cancer immunotherapy: non-standard solution — non-standard respons
Authors: Gluzman M. I. , Tyukavina N. V. , Rudenko D.  S. , Orlova R. V.
Published: April 2024

Ovarian cancer is a serious problem in clinical oncology due to the frequent detection of the disease in late stages, as well as the extremely low effectiveness of treatment at the stage of development of resistance to platinum drugs. The use of immunotherapy in this setting is not a standard option, but several early phase trials of its potential effectiveness are described in the literature. This clinical case presents a successful experience with the use of immune checkpoint inhibitors in a pretreated patient with platinum-resistant metastatic ovarian cancer, which was accompanied by various immune-related adverse events.
Typical metastases, atypical course of the disease and morphology
Authors: Belyak N. P. , Androsova A. V.
Published: April 2024

The process of tumor differentiation is a central aspect of the histopathological classification of solid malignancies and is closely related to the biological behavior of the tumor (poorly differentiated tumors/dedifferentiated tumors are known to be more aggressive than more differentiated tumors). The mechanisms by which tumor cell differentiation is disrupted are poorly understood, but pathologists and molecular tumor biologists have introduced the concept of dedifferentiation to explain the phenotypic changes that occur in solid tumors. In this review, we discuss a case of detection of dedifferentiated cancer, where even with the help of molecular testing of a tumor sample, we were not completely able to unambiguously determine the original source of the process, which entailed difficulties in choosing treatment tactics. And the main question that we asked ourselves during the treatment process: should treatment be based on molecular markers identified in the tumor, or should treatment be carried out according to the recommendations for the treatment of tumors of an undetected primary location with empirically selected chemotherapy?
Clinico-morphological characteristics of SMARCA4-deficient lung cancer
Authors: Orlova R.  V. , Raskin G. A. , Morozova A. S. , Fedorova A. V.
Published: April 2024

Background. Mutations in the SMARCA4 gene of the SWI/SNF chromatin remodeling complex occur in 10% of nonsmall cell lung cancer (NMRL). SMARCA4-deficient lung tumors are aggressive neoplasm with poor outcome. Morphological, immunohistochemical and clinical description of this tumor type is lacking.

The aim of the study was to investigate clinical and morphological characteristics and frequency of SMARCA4 expression loss in patients with lung tumors.

Material and methods. Specimens from a total 100 non-small cell lung cancer cases were immunohistochemically examined for expression of SMARCA4 and SMARCA2. EGFR, BRAF mutations and gene rearrangement of ALK or ROS1 were tested by immunohistochemical, PCR-based or FISH techniques among cases with loss of SMARCA4 expression.

Results. Loss of SMARCA4 expression was detected in 14 (14%) cases. Most of them are men — 93%. The average age was 63 years. In most cases (64%) SMARCA4-deficient tumors have been diagnosed as adenocarcinoma. The mutation was significantly associated with smoking history (p-value 0.009). Mutations in EGFR, BRAF genes and rearrangement of ALK or ROS1 in the SMARCA4-deficient tumor group have not been detected.

Conclusion.  SMARCA4-deficient tumors are subgroup of NMRL, prevalent in smoking men and diagnosed as lung adenocarcinoma without activating mutations.
Des labels aires protégées entre rejets et appropriation par les élus locaux. Le cas des labels Géoparc, Réserve de Biosphère et Parc naturel régional en Luberon
Authors: Bertetto Alizée , Cadoret Anne
Published: April 2024

Face à l’urgence environnementale, les espaces naturels labellisés sont de plus en plus sollicités dans le but de correspondre aux exigences de développement durable. Enjeu majeur pour la conservation de la biodiversité, mais aussi pour les territoires qui cherchent à protéger et à valoriser leurs patrimoines tant naturels que culturels au bénéfice d’un développement local, les labels deviennent des objets politiques. Cette contribution porte sur un territoire en particulier : le Luberon, espace bénéficiant de trois labels espaces protégés dont les périmètres sont presque identiques : un Parc naturel régional (PNR), une Réserve de biosphère et un Géoparc, faisant ainsi de cet espace un parfait exemple de la mise en marque du territoire à l’échelle nationale et internationale au travers de labels espaces naturels protégés. Le PNR du Luberon est actuellement dans un processus de renouvellement de sa charte, accentuant les enjeux autour de l’appropriation de ses labels par la population et par les élus. Il nous a semblé pertinent de mener une étude en géographie sociale sur le regard que portent les élus sur ces trois labels. À partir d’une série d’entretiens semi-directifs auprès d’agents et d’élus locaux, il ressort que les apports de ces labels pour les territoires à l’échelle des communes sont pluriels, que leur maîtrise et leur appropriation par les élus restent fragiles, constituant des signaux d’alerte méritant l’attention des porteurs du renouvellement de la charte.