bluuebunny/crossref_metadata_2025 huggingface dataset:
Der Pester Lloyd als Quelle musikhistorischer Forschungen •
Authors: Ujvári Hedvig
Published: June 2023

The cultural exchange processes can also be formulated from the point of view of transfer research, because plurality and hybrid cultures are primarily characteristic of the Central European communication space. The actors of these cultural mediation processes, who had the authority to shape and transport knowledge and culture, were authors, translators, publishers, journalists, and critics. As far as the research initiative of the author of this study is concerned, which focuses on the period between 1867 and the turn of the century (around 1900), it must be stated that this period has so far been only sparsely investigated. As a result of our own wide-ranging press-historical research, a cultural-historical database of the most important German-language organs of this epoch was created, whereby the focus was primarily on the culture section, mainly on the feuilleton yield of these newspapers. In addition to literature and theater, there was also intensive reference to neighboring disciplines, since art criticism, art history and, last but not least, the musical stages in Pest and Vienna were given plenty of space in these organs. In the following, an overview of the history of the press is given in a compact form, followed by selected finds on the subject of music from the last third of the nineteenth century.
Béta-thalassaemia, B12-vitamin-hiány és társuló komplementmediált hemolízis
Authors: Pethő Ákos Géza , Nagy Zsófia Flóra , Mezei Zoltán András , Takács István , Demeter Judit
Published: June 2023

Közleményünkben egy 67 éves férfi beteg esetét mutatjuk be. A beteget gyengeség
és ismételt szédülés miatt vettük fel Klinikánkra. Laborvizsgálatai súlyos
microcytás vérszegénységet jeleztek, emiatt a felvételt követő napokban 6 egység
választott vér transzfúziójára szorult. Betegünknél a kivizsgálása során
béta-thalassaemia minor igazolódott, melyhez súlyos B12-vitamin-hiány
is társult. Meglepő módon a B12-vitamin-hiánnyal párhuzamosan
komplement mediálta autoimmun hemolízisre utaló laboreltéréseket is észleltünk.
A beteg vérképe a B12-vitamin-hiány korrigálását követően
rendeződött, és az észlelt immunológiai eltérések is megszűntek. A hemoglobingén
genetikai vizsgálata a c.118C>T (p.Gln40STOP) variánst heterozigóta formában
igazolta. A béta-thalassaemia viszonylag gyakori hematológiai megbetegedésnek
számít, bár Magyarországon ritkán találkozhatunk vele. A betegek genetikai
vizsgálata a Debreceni Klinikai Központ Laboratóriumi Medicina Intézetében
lehetséges. Publikált hazai epidemiológiai adatokról nincs pontos tudomásunk. A
diagnózis felállítását nehezítheti, ha a kórkép más hematológiai
rendellenességekkel is kombinálódik, mint a B12-vitamin
hiánya, mely bizonyos vonásaiban a hemolitikus vérszegénységet képes klinikailag
utánozni. Esetünk irodalmi ritkaságnak számít, ezért pozitív családi anamnézis
esetén javasolható az egyenes ági családtagok szűrése, mely esetleg
megkönnyítheti egy későbbi diagnózis pontos felállítását. Orv Hetil. 2023;
164(24): 954–960.
Comparison of the Fisher-Yates Shuffle and the Linear Congruent Algorithm for Randomizing Questions in Nahwu Learning Multimedia
Authors: Saokani Ukan , Irfan Mohamad , Maylawati Dian Sa'adillah , Abidin Rachmat Jaenal , Taufik Ichsan , Hay's Riyan Naufal
Published: June 2023

Nahwu Quiz is a basic Arabic learning application that can be played by the public over the age of 12 years. In the question practice menu, there are questions and 4 multiple choice questions. The user only needs to choose one of the multiple choices that the user thinks is correct/matches the question at hand. In one game, there are 5 questions. After answering all these questions, you will immediately see the score. The purpose of developing this application apart from being a medium of entertainment as well as a medium of learning and memory training for game users (users). To make this Nahwu Quiz application, the authors use the Fisher Yates Shuffle (FYS) algorithm which is used to perform the randomization function in multiple choice and the Linear Congruent Method (LCM) algorithm as a comparison. White box and black box testing were applied to see the feasibility of the program and to obtain efficiency in the comparison of randomization methods. The results of white box and black box testing on the application show that the application is feasible. with reference to the white box test results that the FYS algorithm and the LCM have the same complexity as the result of cyclomatic complexity = 2.
Maintaining Religious Harmony through Predicting the Level of Lawlessness using Linear Regression
Authors: Wardana Adam , Aldamawan Dekis , Lillah M. Rival Ridautal , Wirahadi Mochamad Anwar , Ridho Mohamad Rasyid , Rizqullah Naufal
Published: June 2023

Crimes are basically committed due to low human faith and ultimately disrupt harmony, including inter-religious harmony. Therefore, the purpose of this study is to predict and determine the number of law violations that occurred in Yogyakarta Province in 2022 as a case study using a linear regression algorithm based on data ranging from 2012 to some of the data on law violations in 2022. The method used is the forecasting method in which the stages of data collection, data preprocessing, data modeling, and prediction processes are carried out. The accuracy of the linear regression model is 90%. However, there is a difference in accuracy between the training data and the test data. The training data gets an accuracy of 99% while the accuracy achieved by the test data is at 94% which is 5% lower than the training data. The prediction results using the linear regression model shows the number of the data on law violation that will occur in 2022 with correlation between crimes.
Effect of Fluensulfone on Meloidogyne incognita in onion crop.
Authors: Cabrera-Hidalgo A. J. , Hernández-García A. S. , Navarro-Carvajal D. J. , Acuña-Soto J. A. , Marban-Mendoza Nahum
Published: June 2023

Onion is a plant widely cultivated in the world, only behind potato and tomato. Mexico produces 1,487,102 t in an area of ​​47,952 ha. In this study, the nematode associated with onion cv. Cirrus was identified morphologically and molecularly, and the effect of fluensulfone (1.75, 2 and 2.25 L ha-1) and fenamiphos (7 L ha-1) on the nematode population and crop damage were evaluated. The species associated with onion plants was Meloidogyne incognita. The preventive application of fluensulfone decreased the negative effect of M. incognita on onion yield, providing a good control on the nematode population higher the fenamiphos. At 60 days after sowing (das), Fluensulfone (2 and 2.25 L ha-1) reduced the population and damage caused by M. incognita by 76-78 % and 72-80 % respectively compared with the untreated plants. At 90 das, root galling was less than 15 %. Plants treated with fluensulfone (2.25 L ha-1) and fenamiphos increased the production of commercial bulbs up to 14 % compared with untreated plants. Therefore, the application of fluensulfone for the management of M. incognita in onion crop is recommended, as part of an integrated management plan of root-knot nematodes.
Elective pediatric surgery: profile description of children and late referral identification
Authors: TALINI CAROLINA , CARVALHO ARIANA RODRIGUES DA SILVA , VIERA CLAUDIA SILVEIRA
Published: June 2023

ABSTRACT Pediatric surgery receives great demand for referrals from primary care services in order to evaluate the need for surgical intervention. However access to this specialized evaluation and in intervention does not always occur at the appropriate time. This study aims to characterize the profile of pediatric patients electively operated in the western Paraná state region, between 2018 and 2020, and identify those who were lately referred to surgical evaluation. This is a descriptive, cross-sectional and retrospective study through the review of electronic medical records. The variables evaluated were sociodemographic data, information on underlying diseases, referral data, specialist assessment and surgical procedure. During this period, 410 patients underwent an elective surgical procedure, of which 289 were included in the research. The sample was predominantly male (72.3%) with a mean age of 57.9 months at the surgeons assessment and 59 months at the date of surgery. Most of the patients came from primary care (75%) and the most common pathology was inguinal hernia (39.1%). The mean time interval between referral through primary care and surgery was 4.98 months, and between the surgeons assessment and surgery was 1.21 months. Of the total sample, 77 (26.6%) patients were identified as being referred late for the surgical procedure. Knowing the profile of patients and the problems experienced in this region in relation to the care provided in pediatric surgery provides subsidies to propose improvement strategies not only for the health system in this location, but for several inner regions of Brazil in a similar situation.
Reforma monetária e fiscal para o combate à inflação no Japão pós-Segunda Guerra Mundial (1945-1951)
Authors: MIYAZAKI SILVIO YOSHIRO MIZUGUCHI
Published: June 2023

RESUMO Este artigo analisa o processo inflacionário japonês ocorrido no período após a Segunda Guerra Mundial, entre 1945-1950, suas causas e as políticas de estabilização, reformas monetárias e fiscais. Inicialmente, analisa as fábricas que aumentaram o nível de preços. As medidas adotadas para reverter esse processo foram divididas em dois subperíodos: fase 1 (entre 1946-1948) e fase 2 (entre 1949-1951). Essas políticas e reformas econômicas resultaram em uma estabilização econômica.
1992 - A estabilização necessária
Authors: BRESSER-PEREIRA LUIZ CARLOS
Published: June 2023

RESUMO Este ensaio tenta responder à pergunta: por que o Brasil não consegue estabilizar sua economia? Três respostas complementares podem ser avaliadas: i) um ajuste fiscal é necessário, mas não promulgado; ii) não há capacidade técnica suficiente; e, iii) o país carece de vontade política. Estes não são mutuamente exclusivos e são tratados ao longo do texto ao mesmo tempo que se mostra que a abordagem gradualista não é possível.
O conselho da moeda: um órgão emissor independente
Authors: RESENDE ANDRÉ LARA
Published: June 2023

RESUMO Um programa de estabilização bem-sucedido é um conjunto harmônico de reformas estruturais. O equilíbrio fiscal não é uma condição suficiente. É necessário restabelecer a credibilidade monetária. Três alternativas para estabelecer uma referência monetária com base em uma moeda estrangeira são examinadas. Uma nova moeda emitida por uma instituição independente totalmente lastreada por uma moeda de reserva aceita internacionalmente é a alternativa proposta. Argumenta-se que a instituição responsável pela emissão da nova moeda deve se basear na experiência dos Conselhos de Moeda. A supervalorização da moeda devido à inflação inercial residual é um problema frequente. A introdução gradual da nova moeda conversível é proposta como uma tentativa de reduzir o grau de referência à inflação passada na formação de preços. Os riscos associados a um período de circulação paralela de duas moedas são examinados. Finalmente, alguns dos argumentos contra esse tipo de reforma monetária são analisados brevemente.
Bioactive compounds of Eugenia punicifolia fruits: a rich source of lycopene
Authors: Braga Elaine Cristina de Oliveira , Pacheco Sidney , Santiago Manuela Cristina Pessanha de Araujo , Godoy Ronoel Luiz de Oliveira , Jesus Monalisa Santana Coelho de , Martins Víctor de Carvalho , Souza Marcelo da Costa , Porte Alexandre , Borguini Renata Galhardo
Published: June 2023

Abstract This work aimed to characterize some of the bioactive compounds of Eugenia punicifolia (Kunth) DC. fruit to enhance the knowledge of its functional potential. Ripe fruits were collected from the restinga of Maricá, in the state of Rio de Janeiro (RJ), Brazil. Bioactive compounds were analyzed by High Performance Liquid Chromatography (HPLC). Ascorbic acid (74.14 mg 100-1 g-1), lycopene (504 µg g-1) and total carotenoids (632 µg g-1) contents were superior to other fruits rich in these compounds. In fact, E. punicifolia fruits are an excellent source of carotenoids and can be considered a good source of ascorbic acid (vitamin C). Furthermore, its chemical composition has presented phenolic compounds like gallic acid and anthocyanins. Thus, this underutilized Brazilian fruit stands out as a source of bioactive compounds, presenting a good potential as a functional food, especially due to the high content of lycopene.
Bearing capacity of footings on geosynthetic-reinforced soils under combined loading
Authors: Yaghoobi B. , Fathipour H. , Payan M. , Jamshidi Chenari R.
Published: June 2023

In this study, the ultimate bearing capacity of shallow strip footings resting on a geosynthetic-reinforced soil mass subjected to inclined and eccentric combined loading is rigorously examined through the well-established method of lower bound limit analysis (LA) in conjunction with finite element (FE) and second-order cone programming (SOCP). Lower bound limit analysis formulation is modified to consider the ultimate tensile force of the geosynthetic layer in the soil mass so as to account for both pullout (sliding) and rupture (structural) modes of reinforcement failure. The effects of several parameters, including the embedment depth (u) and the ultimate tensile strength (Tu) of the geosynthetic layer along with load inclination angle (α) and load eccentricity (e), on the bearing capacity ratio (BCR) and failure envelopes of the overlying shallow foundation are examined and discussed. The results generally show a marked increase in the ultimate bearing capacity of the surface footing against combined loading with the inclusion of a single geosynthetic layer. Results also reveal that a second intermediate reinforcement might be required to bear a dual performance against both vertical concentric and combined loading scenarios so as to more effectively support the footing.
Poor response to Eculizumab in Caucasian Patients with Treatment Refractory Generalized Myasthenia Gravis: A case series
Authors: Katyal Nakul , Govindarajan Raghav
Published: June 2023

Background

Eculizumab, a C5 complement inhibitor, has been approved for management of patients with treatment refractory Acetylcholine receptor positive (AChR+) Generalized Myasthenia Gravis (gMG). Though majority of patients receiving eculizumab experience clinical improvement, a small number of patients may have poor response.

 

Objective

To report three cases of poor response to eculizumab in young caucasian patients with treatment refractory gMG.

 

Methods

Case Series

 

Results

All three patients were young, caucasian, thymectomized, females with MGFA class III, treatment refractory MG on multiple immunosuppressant medications. All three patients had initial worsening of MG- ADL score, 1 month post eculizumab, followed by an unchanged MG ADL and MGC score, 3 months after eculizumab therapy.  No changes were noted in the number of acute exacerbations of MG, pre and post eculizumab therapy. All patients were eventually started on maintenance Plasma-exchange (PLEX) therapy, post eculizumab failure and had clinical improvement in MG-ADL and MGC scores and reduction in the number of acute exacerbations of disease.

 

Conclusion

The exact mechanism contributing to poor clinical response to eculizumab in gMG patients remains unclear. Further studies are warranted to undermine the underlying pathogenesis.
A novel MUSK mutation in a patient with CMS9
Authors: Elliott Jeffrey
Published: June 2023

Congenital myasthenic syndromes (CMS) are a relatively rare cause of fatigable muscle weakness often with significant ocular, bulbar and respiratory impairment1. Mutations in the gene encoding muscle specific tyrosine kinase (MuSK) can lead to abnormal endplate and acetylcholine receptor functioning and cause an autosomal recessive post-synaptic CMS (CMS9). Only 23 patients with CMS9 have been characterized in the literature since the initial description in 20042.  Here, we report a newly diagnosed case of CMS9 in a 23-year-old female who harbored a novel c.296G>T (Cys99Phe) mutation in the MUSK gene, thereby expanding the phenotypic/genotypic characterization of this rare disorder.
Facial Onset Sensory and Motor Neuronopathy: A Case Series and Literature Review
Authors: Morena Jonathan , Kamdar Hera , Yasin Rabia , Hoyle J. Chad , Quick Adam , Kolb Stephen
Published: June 2023

Introduction: Facial Onset Sensory and Motor Neuronopathy (FOSMN) typically presents with paresthesias in the trigeminal nerve distribution and weakness that progresses rostro-caudally.

Objective: To present two new cases of FOSMN, summarize the current literature, and address areas for future study.

Methods: Observational data was collected from two patients with FOSMN from our institution. A literature review of FOSMN was completed using PubMed.

Results: We identified 100 cases of FOSMN, including our two new cases. 93% presented with facial paresthesias. 97% had bulbar symptoms. Five had family history of ALS. Abnormal Blink reflex was most common on EMG/NCS. CSF was typically normal, but a rare severe case showed elevated protein. Mutations included: TARDBP, OPMD, D90A-SOD1, CHCHD10, VCP, and SQSTM1. Neuropathological studies showed neurodegenerative changes without inflammation. Some cases have reported transient stabilization or improvement to immunomodulatory therapy.

Case Reports: A 72-year-old man presented with right-sided trigeminal paresthesias that progressed in a rostro-caudal fashion, dysphagia, and hand weakness. He died 4-5 years after symptom onset. A 69-year-old man presented with left-sided jaw paresthesias, dysphagia and dysarthria. He was trialed on IVIG for 1.5 years without improvement and died 2.6 years after symptom onset.

Conclusion: FOSMN is a rare disorder with a unique clinical and electrophysiological phenotype. The pathophysiology has been associated with neurodegeneration and multiple gene mutations have correlated to FOSMN. Some reports suggest transient response to immunomodulatory therapy, though prospective studies are lacking. CSF protein elevation may be seen in severe disease. Future studies will help further elucidate the approach to diagnosis, treatment, and prognostic counseling (biomarkers).
The impact of the COVID-19 pandemic on parents seeking dental care for their children
Authors: Sara Toema , Chukwuebuka Ogwo , Nikita Patel , Caileigh Fritz , Alexandria Catalano , Angelica Saclayan , Salwa Mekled
Published: June 2023

Many changes in routine dental care were implemented to protect dentists and patients during the COVID-19 pandemic. Pediatric dentists face unique challenges in dealing with parental fears and behavioral changes in pediatric patients. Despite the meticulous infection control protocols that dental offices have implemented during the pandemic, they experienced significant reductions in routine recall. The aim of this study is to assess the impact of the SARS-CoV-2 pandemic on parents seeking dental care for their children at the Temple Kornberg School of Dentistry (TUKSoD). Parents who currently have their children treated at the TUKSoD were invited to participate in a questionnaire. One hundred and six parents completed the survey anonymously on paper. The survey focused on parents’ attitude changes towards dental care for their children post-pandemic. Bivariate analysis followed by a Two-way ANOVA test was used to calculate the association between the effect of the COVID-19 pandemic on parents of pediatric patients’ decision to seek dental care versus the age of the child. Our results showed that improved dental protocols increased the likelihood of parents bringing their children to the dentist during the COVID pandemic (p < 0.001). The results help pediatric dentists to build trust among their patients during the pandemic. It will also help policymakers understand the pediatric patients’ parents’ concerns and assess their current safety measures. Ultimately, this study will give practitioners more insight into how to handle outbreaks of new COVID-19 variants that may present in the future.
Kidney Functional Tissue Unit (FTU) Segmentation v1
Authors: Heath Patterson Nathan
Published: June 2023

This protocol explains how to apply a segmentation model to autofluorescence microscopy images to find kidney functional tissue units (FTUs). Currently the model allows for segmentation of glomeruli, proximal tubules, thick ascending limb, distal tubules, and collecting ducts.
Multi-Class Heart Abnormalities Detection Based on ECG Graph Using Transfer Learning Method
Authors: Hadiyoso Sugondo , Aulia Suci , Irawati Indrarini Dyah
Published: June 2023

The heart is one of the vital organs in the circulatory system. Regular checkups are very important to prevent heart disease. The most basic examination is blood pressure then further examination is related to the evaluation of the electrical activity of the heart using an electrocardiogram (ECG). The ECG carries important information regarding various abnormalities of heart function. Several automated classification techniques have been proposed to facilitate diagnosis. However, not all digital ECG devices provide raw data for analysis. ECG classification method based on images can be an alternative in classification. Therefore, in this study, it is proposed to classify ECG based on signal images. The proposed classification method uses transfer learning with VGG, AlexNet, and DenseNet architectures. The method used for the classification of multi-class ECG consists of normal, PVC, Atrial Fibrilation, AFL, Bigeminy, LBBB, and APB. The simulation results generate the best accuracy of 92% and F1-score of 92%. Best performance is achieved using DenseNet architecture at 60 epochs. This study is expected to be a new reference technique in the classification of ECG signals.
POINT OF CARE PCR FOR INFLUENZA AND RESPIRATORY SYNCYTIAL VIRUS: FROM THE LAB TO THE EMERGENCY ROOM
Authors: Marçolla Weber Fernanda , Schrage Lin Rodrigo , Michelin Lessandra
Published: June 2023

RNA viruses, such as influenza and respiratory syncytial virus (RSV), are common causes of lower airway infections. Rapid tests (antigen-based by immunochromatographic and molecular technique - RIT and RMT, respectively) with good diagnostic accuracy directly impacts the quality of patient care and hospitalization costs. This study aims to evaluate the implementation of point of care PCR compared to rapid antigen-based tests for influenza and RSV in the emergency department.Methods: Prospective cross section study in an Emergency Room (ER) from August to September 2019, where all patients with influenza like illness went through RIT and RMT. The patients were divided in a model of four clinical scenarios to evaluate cost and isolation time in the ER.Results: 424 patients were included in the study. RIT showed sensitivity of only 40% compared with RMT (100% specificity; PPV 100%; NPV 68,7%), causing 103 patients to mistakenly leave respiratory isolation, raising biological risk in the ER. Fast results from RMT led negative patients to leave isolation early (262:10 less hours of isolation), allowing cost reduction of USD 1.921,20. Nonetheless, RMT had higher cost than RIT in all clinical scenarios with an increase of USD 12.788,90 (69,9% of cost related to tests and isolation precautions). Conclusion: RIT was a more affordable test but can’t be used to exclude disease and was associated with higher biological risk to the hospital setting. RMT had better diagnostic performance with faster results, allowing for less isolation time per patient tested.
Estimating potential future distribution of some selected Oak species in the Marmara Region
Authors: FOSSO Lionel Constantin , KARAHALİL Uzay , ÖZDEMİR Mehmet , SONUÇ Cemre Yürük , DİREN ÜSTÜN Deniz Hazel , ÜNAL Yurdanur , TANDOĞAN Mesut
Published: June 2023

In this study, climate simulations were obtained by reducing the global model results to 2.5 km resolution with the COSMO-CLM model with a dynamic downscaling approach. Bioclimatic variables corresponding to the reference years 2031-2040, 2051-2060, 2071-2080 and 2091-2100 were calculated by using high-resolution meteorological parameters produced from the current and future RCP8.5 emission scenario. With the help of the MaxEnt program run with these variables, habitat suitability analysis was carried out for Quercus frainetto, Q. cerris, Q. petraea and Q. infectoria species distributed in the Marmara Region. When examining the obtained results, it has been concluded that the areas of Quercus frainetto, Q. cerris and Q. petraea increase while the area of Quercus infectoria decrease. It has been revealed that the suitable areas for Quercus frainetto increase from 2020 to 2050, but the highly suitable areas decrease from 2050 to 2070. Furthermore, it has been found that there will be an increase in the highly suitable areas from 2070 to 2100, while both less suitable and suitable areas will experience a decrease. It has been determined that future climatic conditions will increase the habitat suitability of Quercus cerris and Q. petraea and will create the most favourable conditions for their establishment. In contrast, it has been observed that the suitable areas for Quercus infectoria are projected to increase from 2020 to 2050 but decrease from 2050 to 2070 and subsequently from 2070 to 2100.
Spatial area distribution of Oaks according to different selected parameters in Türkiye
Authors: FOSSO Lionel Constantin , KARAHALİL Uzay
Published: June 2023

Considering the recently prepared forest management plans, Oaks, which were previously represented by a single nickname (Quercus spp), are now separated based on their species. Although there are still forest management plans that are using old pseudonyms, the plans that have expired are being renewed while taking into account the distinction between Oak species. There is no study that provides up-to-date information on the spatial distribution, mixture status, and stands’ distribution according to age, site and canopy classes. However, such studies provide valuable information at various levels, ranging from sectorial planning to revealing honey production efficiencies.This study examines the spatial distribution of Oaks across different parameters mentioned above by using the spatial database obtained from the General Directorate of Forestry. ArcGIS 10.8TM software was used to query the attribute data and present it in tables and figures. According to the results obtained, there are a total of 9.05 million ha of Oak stands, of which, 6,116,992.7 ha (67.6%) are pure or mixed within Oak species, and 2,928,775.9 ha (32.4%) are mixed. Pure and mixed stands within Oak species have 2,075,508.4 ha of productive (33.9%) and 4,041,484.3 ha degraded (66.1%). Moreover, 4,986,288.1 ha (81.5%) are managed as high forest and 1,130,704.6 ha (18.5%) are managed as coppice. Considering their developmental stage and crown closure (excluding degraded stands), 94.5% of those were less than 20 cm in dbh (diameter at breast height), with 44.1% of them having more than 70% of the cover. In conclusion, it is recommended that the parameters mentioned above be considered when publishing forestry statistics for Oaks.
Elder People and Personal Data: New Challenges in Health Platformization
Authors: Rivoir Ana , Reilly Katherine
Published: June 2023

In Uruguay, as in many countries around the world, healthcare providers are looking to digital technologies to enhance service provision. This includes introducing new data-intensive systems that facilitate connections between healthcare providers and patients and maintaining records of these interactions. This article considers the numeric ability of older citizens to critically assess the implications of platformization and datafication within the Uruguayan healthcare system with a view to identifying implications for digital literacy programs. The ability of older people to manage their personal data within healthcare systems shapes their ability to enact citizenship and human rights. This reality came into sharp relief during the recent Covid-19 pandemic, demonstrating the extent to which core social services have become datafied and digitally mediated, as well as their potential to deepen digital divides where senior citizens are concerned. Critical perspectives on technological change, well-being, and ageing offer useful perspectives on this challenge. Drawing inspiration from these perspectives, in this article, we explore the results of a digital literacy initiative that worked with 16 seniors to explore their experiences of personal data collection within Uruguay’s new National Comprehensive Health System. Our approach simultaneously worked to build digital literacy while also revealing the complex relationships and disconnections between the ontological frameworks mapped onto healthcare by systems designers and the reality of older people. In the conclusions, we consider the implications of these observations for seniors’ digital literacy interventions that foster seniors’ critical understanding of their data subjectivity in the context of local healthcare systems.
MODELO OU MODELAGEM DE TÓPICOS: UMA INVESTIGAÇÃO BIBLIOMÉTRICA E SOCIOMÉTRICA DE SUA PRODUÇÃO CIENTÍFICA DIVULGADA NO PERIÓDICO INTERNACIONAL SCIENTOMETRICS
Authors: Ribeiro Henrique César Melo
Published: June 2023

O objetivo deste estudo foi investigar o perfil da produção científica e das redes de colaboração do tema Topic Model / Modeling divulgado no journal internacional Scientometrics. Metodologicamente, utilizou-se as técnicas da bibliometria e da sociometria em 50 estudos publicados no citado periódico de 2012 a junho de 2021. Uma síntese dos principais achados foram: crescimento do tema modelo / modelagem de tópicos a partir de 2018. Min Song foi o pesquisador mais profícuo. A instituição e o departamento o qual o citado autor faz parte foram as mais proficientes e, também os mais relevantes e posicionais no que enfoca a centralidade de grau. A China, a Coreia do Sul e os Estados Unidos da América (EUA) foram os países com maior produção científica sobre o citado tema, contudo, os EUA foi a não com maior proeminência em relação as redes de colaboração. De maneira, os resultados evidenciados neste estudo contemplam uma visão direcional sobre o assunto topic model / modeling, pois, se norteou pela produção científica da revista internacional Scientometrics em decorrência desta ser uma das mais relevantes e influentes na literatura cientifica da área.
 
Palavras-chave: Topic model / modeling; Scientometrics; Produção científica; Bibliometria; Sociometria.
Consensus concept of modern effective therapy for Duchenne muscular dystrophy
Authors: Gremyakova T. A. , Artemyeva S. B. , Baybarina E. N. , Vashakmadze N. D. , Guzeva V. I. , Gusakova E. V. , Kuzenkova L. M. , Lavrova A. E. , Lvova O. A. , Mikhaylova S. V. , Nazarenko L. P. , Nikitin S. S. , Polyakov A. V. , Dadali E. L. , Rumyantsev A. G. , Sakbaeva G. E. , Suslov V. M. , Gremyakova O. I. , Stepanov A. A. , Shakhovskaya N. I.
Published: June 2023

Duchenne muscular dystrophy is a genetic orphan neuromuscular disease caused by a mutation in the DMD gene encoding the protein dystrophin. As a result of developing and progressive muscle damage and atrophy, children lose the ability to walk, develop respiratory and cardiac disorders. The core elements of good care standards are early diagnosis, prevention and treatment of osteoporosis, daily physical therapy, regular rehabilitation, glucocorticosteroids, and control of heart and lung function. The clinical effect of new targeted pathogenetic therapies for Duchenne muscular dystrophy, restoring synthesis of full or truncated dystrophin, depend on their appropriate combination with existing standards of care.
Phenotypic variability in TRPV4-associated neuropathies and neuronopathies: a case series
Authors: Murtazina A. F. , Tsabay P. N. , Rudenskaya G. E. , Bessonova L. A. , Bostanova F. M. , Guseva D. M. , Sharkova I. V. , Shchagina O. A. , Orlova A. A. , Ryzhkova O. P. , Markova T. V. , Kuchina A. S. , Nikitin S. S. , Dadali E. L.
Published: June 2023

TRPV4‑associated neuromuscular diseases represent a clinical spectrum of neuropathies and motor neuron disorders. To date, 3 phenotypic forms are distinguished. There are Charcot–Marie–Tooth disease type 2C, distal hereditary motor neuropathy type 8 (DHMN8), scapulo‑peroneal spinal muscular atrophy (SPSMA). Here we report 3 families with DNMN8 and one family with SPSMA. In all cases, DNA‑analysis revealed single nucleotide variants in the TRPV4 gene previously reported as pathogenic. In 3 probands, a combination of signs of both motor and motor‑sensory neuropathies led to difficulties in the establishment of the clinical diagnosis. Patients had mild sensory disturbances in the feet, but in all of these cases nerve conduction study revealed normal sensory nerve action potentials. Considering the prevailing signs of motor neuropathy, these patients were diagnosed with DNMN8. Clinical signs of sensory disturbances are regarded as not  contradicting  the  diagnosis,  since  they  can  be  observed  in  various  forms  of  distal  motor  neuropathies. The clinical features of SPSMA in one patient corresponded to those previously described in the literature. The involvement of the shoulder girdle muscles and the peroneal muscles and neurogenic changes in needle electromyography allow suspecting SPSMA clinically. A distinctive features of TRPV4‑associated neuromuscular diseases are the vocal cords paresis, sensorineural hearing loss and respiratory failure, however they are not obligatory according to our clinical reports.
Memahami upaya preventif pencegahan tindakan kekerasan seksual melalui penyuluhan kepada siswa
Authors: Muzaki Alfian Nur , Rosyida Fatiya , Mutia Tuti , Putri Adinda Aprilia , Ladisha Arsya Fitrilia , Tantular Audy Bintang , Yanuariska Aulia Winan , Azizah Berty Zulfa Nur , Wulan Cahyaning
Published: June 2023

Acts sexual violence have a very negative impact on someone who receives it. The impact greatly affected his physical and psychological condition. Due to the absence of sex education and taboos to discuss sexual studies. Therefore, counseling activities are need to educate students about the risk of sexual violence. The counseling activity took place at Muhammadiyah 1 Middle School Malang City with the subject of class VIII students totaling 30th students. This study use qualitative methodology, including of interviews, observing, and documenting. Methods of data analyzis via descriptive analyze. The extension team also distributed pre-test and post-test. Averages value of pre-test outcomes was 58,8333, while value result of 84 for post-test. Preventive efforts to prevent sexual violence are through counseling on the dangers of sexual violence, integrated services, and collaboration between children and their parents. Thus, these preventive efforts can tolerate sexual inflicted by students.

Tindakan kekerasan seksual sangat berdampak negatif bagi seseorang yang menerimanya. Dampak tersebut sangat mempengaruhi kondisi fisik dan psikologisnya. Hal itu disebabkan karena kurangnya pendidikan seks dan tabu untuk membicarakan kajian seksual. Oleh karena itu, dibutuhkan kegiatan penyuluhan untuk memberikan pengetahuan kepada peserta didik dari bahaya kekerasan seksual. Kegiatan penyuluhan bertempat di SMP Muhammadiyah 1 Kota Malang dengan subjek peserta didik kelas VIII dengan jumlah 30 peserta didik. Metode yang digunakan adalah kualitatif meliputi wawancara, pengamatan langsung, dan dokumentasi. Analisis data menggunakan teknik desciptive analyzis. Tim penyuluh juga membagikan pre-test dan post-test. Luaran pre-test didapatkan nilai rerata 58,8333 dan luaran post-test didapatkan nilai rerata 84. Upaya preventif untuk mencegah kekerasan seksual yaitu melalui penyuluhan bahaya kekerasan seksual, layanan terpadu, dan kolaborasi anak dengan orangtuanya. Dengan demikian, upaya preventif tersebut dapat menanggulangi aksi kekerasan seksual yang dialami oleh peserta didik.
Çalışma Psikolojisi Kuramı Bağlamında İnsana Yakışır İş Modeli
Authors: ERGİN Zeynep Öznur , KİRAZCI Furkan , BÜYÜKGÖZE-KAVAS Ayşenur
Published: June 2023

Çalışma Psikolojisi Kuramı, ekonomik açıdan sınırlı kaynaklara ve ayrımcılığa maruz kalan bireylerin çalışma ile ilgili deneyimlerini incelemek amacıyla geliştirilmiştir. Kuramın merkezinde İnsana Yakışır İş kavramı yer almaktadır ve bu işlere ulaşmayı etkileyen çeşitli bağlamsal ve psikolojik faktörlerin olduğu belirtilmektedir. Bu bağlamda mevcut araştırma, Çalışma Psikolojisi Kuramı temelinde önerilen İnsana Yakışır İş modelinin çalışan yetişkinler üzerinde test edilmesini amaçlamaktadır. Çalışmada 351 katılımcı Ekonomik Kısıtlılıklar Ölçeği, Yaşam Boyu Ötekileştirilme Ölçeği, Çalışma İradesi Ölçeği ve İnsana Yakışır İş Ölçeğini doldurmuşlardır. Verilerin analizinde path (yol) analizi kullanılmıştır. Analiz sonuçlarına göre, ekonomik kısıtlılıklar ve ötekileştirilme çalışma iradesini ve insana yakışır işi negatif ve anlamlı bir şekilde yordarken, çalışma iradesi insana yakışır işi pozitif ve anlamlı bir şekilde yordamaktadır ve modeldeki tüm değişkeler insana yakışır işin %38’ini açıklamaktadır. Ayrıca çalışma iradesinin bağlamsal faktörler ile insana yakışır iş arasındaki aracı rolü anlamlı bulunmuştur. Son olarak sonuçlar alanyazın temelinde ele alınmış ve uygulamaya yönelik öneriler geliştirilmiştir.
Meslek Yüksekokulu Öğrencilerinin Endüstri 4.0 ve/veya Toplum 5.0 ile İlişkili Kavramlara Yönelik Farkındalıklarının Geliştirilmesi
Authors: ÇUKURBAŞI Barış , GENÇAY Semih , BAYSAL Emre , KIYICI Gülbin
Published: June 2023

Araştırmada, meslek yüksekokulu öğrencilerinin Endüstri 4.0 ve/veya Toplum 5.0 ile ilişkili kavramlara yönelik farkındalıklarının geliştirilmesi amaçlanmıştır. 2021-2022 akademik yılı güz döneminde meslek yüksekokulu’nda öğrenim gören ve İşletmede Mesleki Eğitim dersini henüz almamış öğrencilerle 7 hafta süren etkinlik gerçekleştirilmiştir. Etkinlikler, öğrencilerin iş ortamlarına girmeden önce Toplum 5.0’a hazırlamaya yönelik 21. yüzyıl becerilerini geliştirici öğrenme faaliyetlerini içermiştir. Araştırmada nicel araştırma yöntemlerinden tek grup öntest-sontest modeli kullanılmıştır. Araştırmanın katılımcılarını meslek yüksekokulunda öğrenim gören 125 öğrenci oluşturmuştur. Veri toplama aracı olarak araştırmacılar tarafından hazırlanmış farkındalık anketi kullanılmıştır. Araştırmanın sonucunda öğrencilerin farkındalıklarının istatistiksel olarak anlamlı düzeyde arttığına ulaşılmıştır. Ayrıca sınıf düzeyine göre anlamlı bir farklılık bulunmamıştır.
Hanehalkı Harcamalarının Gelir Memnuniyeti Üzerindeki Etkilerinin Belirlenmesi
Authors: PAKSOY Semin , ŞAHİN Hande
Published: June 2023

Hanehalkı tüketim harcamaları, günümüzde bir toplumun veya ülkenin en önemli refah göstergelerinden biri olarak kabul edilmektedir. Bu nedenle hanehalkı tüketim harcamalarına etki eden faktörlerlerin belirlenmesine yönelik çalışmalar, araştırmacıların ilgisini çeken başlıca konular arasında yer almaktadır. Tüketim talebinin oluşmasını belirleyen en önemli unsurlardan biri de gelirdir. Bu bağlamda hanehalkı gelir memnuniyeti, adaletli gelir dağılımının önemli bir göstergesi olarak değerlendirilebilir. Dolayısı ile yapılan çalışmada, subjektif bir kavram olan hanehalkı gelir memnuniyetini etkileyen hanehalkı harcamaları ve bunların gelir memnuniyeti üzerindeki etkilerinin ortaya çıkarılması amaçlanmaktadır. Analizde, klasik regresyon modellerinden daha esnek olduğu kabul edilen kantil regresyon yöntemi kullanılmaktadır. Çalışmanın veri setini, Türkiye İstatistik Kurumu’nun web sitesinde yayınlanan, 2003 - 2019 dönemine ait Hanehalkı Bütçe Anketleri yolu ile elde edilen, gruplandırılmış hanehalkı tüketim harcamaları oluşturmaktadır. Sonuç olarak, tüm değişkenlerin tüm kantillerde benzer ve monoton bir kalıpta hanehalkı gelir memnuniyetine katkı sağlıyor olup sadece eğitim hizmetlerinin hanehalkı gelir memnuniyeti üzerinde hiçbir etkisi bulunamamıştır.
Denetçi Cinsiyeti ile Denetim Ücreti Arasındaki İlişki: Türkiye Örneği
Authors: KIYMETLİ ŞEN İlker , TERZİ Serkan
Published: June 2023

Bu çalışmanın amacı, denetçi cinsiyeti ile denetim ücreti arasındaki ilişkinin incelenmesidir. Bu ilişkiyi tespit etmek için 2020 ve 2021 yıllarında Borsa İstanbul’da kote olan 434 şirketin verileri kullanılmıştır. Verilerin analizinde kullanılan değişkenler, literatürdeki çalışmalardan seçilmiştir. Çalışmada denetçi cinsiyetinin denetim ücreti üzerinde etkisi olup olmadığının belirlenmesinde çoklu doğrusal regresyon yöntemi kullanılmış olup, denetçi cinsiyetinin denetim ücreti üzerinde etkisi olduğu tespit edilmiştir. Ayrıca şirketin aktif büyüklüğü ve denetçi cinsiyeti ile denetim ücreti arasında pozitif ve anlamlı ilişki tespit edilmiştir.
Manisa Şer’iyye Sicillerinde Manzum Eserler
Authors: KARADENİZ Ümran , ERDOĞAN Kenan
Published: June 2023

Sicillât-ı şer’iyye, kadı sicilleri, mahkeme defterleri ve yaygın olarak şer’iyye sicilleri adıyla anılan defterler, kadı ya da naipler tarafından kaydedilen i’lam, hüccet, vakfiye, berat ve ferman türünden belgeleri ihtiva etmektedir. Bu bakımdan şer’iyye sicillerinde bulunan belgeler genel anlamda Osmanlı hükümeti ya da devlet adamları tarafından kadılığa gönderilenler ile kadı ya da naipler tarafından düzenlenenler olarak iki kısma ayrılmaktadır. İhtiva ettiği belgeler açısından zengin konu çeşitliliğine sahip olan şer’iyye sicilleri, ekonomi, hukuk ve sosyal tarih alanında önemli kaynaklardır. Bunun yanında sicillerde, kadı, naip ya da katipler tarafından kaydedilmiş notlar ve şiirler de bulunmaktadır. Şiirler, yazan kişinin kültür seviyesini ve ilgi alanını göstermenin ötesinde yazıldığı döneme dair malumat da verebilmektedir. Bu çalışmada, 18. yüzyılın ilk yarısına ait Manisa şer’iyye sicillerinde tespit edilen manzumeler ele alınacaktır. Manzumeleri yazan kadı ya da naipler hakkında malumat verildikten sonra manzum eserler, konunun daha iyi anlaşılması için günümüz Türkçesi ile açıklama ve serbest bir nesre çeviri usulüyle değerlendirilecektir. Bu anlamda Manisa’nın kültürel tarihine ilaveten Klasik Türk Edebiyatı alanına da katkı sağlanması amaçlanmıştır.
Who were the volunteers? A Spanish Revolutionary and Wanderer in Argentina, 1857-1860
Authors: Jacobson Stephen
Published: June 2023

La historia de los voluntarios revolucionarios empieza con las guerras revolucionarias y napoleónicas en Francia, y continúa con las guerras de independencia en Grecia y Latinoamérica, con la invasión francesa de Argelia y con las guerras civiles en la península ibérica y en el Río de la Plata. Al terminar las revoluciones europeas de 1848 y el Bienio Progresista en España (1854-‍1856), muchos exrevolucionarios, exiliados, soldados desmovilizados e inmigrantes continuaron esta tradición. Se alistaron como voluntarios en guerras a favor de la democracia y de la unificación nacional y en campañas liberales de conquista en el nombre de la civilización. Una literatura académica en ciernes se ha ocupado de este fenómeno. Sin embargo, poco se conoce de los voluntarios que no escribieron memorias o que no se convirtieron en protagonistas de biografías romantizadas. Esta microhistoria traza las peripecias de Claudio Feliu, artesano de poca fortuna y miliciano barcelonés que participó en la revolución fallida de 1856 y después viajó a Argentina por razones políticas y personales. Allí tomó parte en una campaña contra los indios (1857-‍1858) y en un ataque naval en lo que entonces se llamó la “Guerra de Unificación Nacional” (1859). Además de ayudarnos a entender las experiencias de los voluntarios corrientes, su vida nos ofrece una ventana para analizar las interconexiones entre el Río de la Plata y el Mediterráneo, así como el internacionalismo popular democrático de mediados del siglo xix.
Defendiendo el «suave yugo» de «la mal llamada esclavitud»: El Círculo Hispano-Ultramarino de Barcelona (1871-1880)
Authors: Rodrigo y Alharilla Martín
Published: June 2023

Barcelona fue el lugar elegido por muchos indianos enriquecidos en Cuba y Puerto Rico al instalarse en Europa. Unos indianos que durante el Sexenio Democrático se organizaron en el Círculo Hispano-Ultramarino de dicha ciudad para presionar por el mantenimiento de la esclavitud en ambas Antillas, primero, y para desestabilizar a la I República, después. Aquella entidad fue capaz de implicar en sus campañas antiabolicionistas y proesclavistas a las principales organizaciones económicas catalanas, así como a amplios sectores de las élites de Cataluña, quienes asumieron públicamente sus argumentos participando en plataformas más amplias como la Liga Nacional o la Comisión Defensora de los Intereses de España en Cuba. Y aunque la presión proesclavista no pudo evitar la abolición de la esclavitud en Puerto Rico y en Cuba, sí consiguió alargar su vigencia durante unos años en la Gran Antilla mediante la institución del Patronato. El legado más destacable (y también el más perdurable) del Círculo Hispano-Ultramarino de Barcelona fue el Banco Hispano Colonial, una entidad financiera nacida en 1876 que acabaría transformándose en un verdadero banco de negocios y que gestionaría las aduanas cubanas hasta el final de la dominación española sobre la isla, en 1898.
Studi Perbandingan Hukum Perwujudan Pertanggungjawaban Pidana Korporasi antara Inggris dan Indonesia
Authors: Dwiyantama Rayhan Wardhana Hascarya
Published: June 2023

A corporation is a legal entity established with a certain amount of capital to carry out business activities in an area. The implementation of corporate activities must comply with all applicable regulations in the region. However, there is the possibility of rules violation, for example, committing a crime so that they must be held responsible. Corporate criminal liability implements in countries such as the UK and Indonesia. The two countries have characteristics related to this aspect, which raises questions regarding the manifestation of corporate criminal responsibility in the UK and Indonesia, including their differences and similarities. This study aims to describe corporate criminal responsibility in England as a pioneer country and Indonesia as a civil law country that had never recognized this practice. The research explanation expects to make the reader aware of the embodiments, differences, and similarities. This study applies a normative juridical method that uses literary sources to answer problems and a comparative law approach to explain the differences and similarities of corporate criminal responsibility. The study results prove that corporate criminal liability in England and Indonesia has characteristics with differences and similarities.
Consumer engagement with augmented reality (AR) in marketing: Exploring the use of ar technology in marketing campaigns and its impact on consumer engagement, brand experiences, and purchase decisions
Authors: Thakkar Krishna Yatin , Joshi Bhavin Bhaskarbhai , Kachhela Prashant Pravinbhai
Published: June 2023

This research paper aims to investigate the role of augmented reality (AR) technology in marketing campaigns and its influence on consumer engagement, brand experiences, and purchase decisions. The study explores the various applications of AR in marketing, analyzes its effectiveness in capturing consumer attention, and examines the outcomes of AR-based campaigns on consumer behavior. Through a comprehensive review of relevant literature and empirical analysis, this paper provides insights into the potential of AR as a strategic tool for enhancing consumer engagement and driving brand success in the modern marketing landscape.

Augmented reality, Marketing, Consumer engagement, Brand experiences, Purchase decisions, AR technology, AR campaigns, Consumer perception, Product evaluation, Decision-making, Brand recall, Brand storytelling, Brand authenticity, AR adoption barriers, Technical limitations, User experience, Privacy concerns, Ethical considerations, Opportunities, challenges, Successful AR marketing campaigns, Case studies, Best practices.