bluuebunny/crossref_metadata_2025 huggingface dataset:
Nie tylko muzyczna droga wirtuoza. O młodości, dorastaniu i życiowej klęsce Romualda z „Książki pamiątek” Narcyzy Żmichowskiej
Authors: Łuczak Bartłomiej
Published: November 2021

This article in its interpretative nature offers a glance at the adolescent years of the main character of the novel, a gifted violinist Romuald. The focus of this insight is placed on the motivation behind the life choices of the virtuoso, including choice between the opportunity to experience fulfilled love and the drive to achieve fame resulting from the commitment to the musical career. The article sketches the psychological portrait of the character, which takes into account changes undergoing within his inner self, in his attitude towards others, as well as in his treatment of music and the violin itself. Light is particularly cast on Romuald, his attitude towards music and his own career at the time of experiencing a growing feeling towards Helusia, a young daughter of a craftsman. The last part of the article deals with psychological and moral dimension of decision made by Helusia, a character who decides to abandon Romuald after learning the truth about his past.
Kobieta u progu życia. Dojrzewanie do miłości, seksualności, przyjaźni w „Kobietach” Zofii Nałkowskiej
Authors: Kaźmierska Anna
Published: November 2021

The debut novel by Zofia Nałkowska, entitled “Women” is a work about youth and maturation to life. The author is raising the motif, which is known and worked out in the literature of many periods, but she writes about it in an unique way. Firstly Nałkowska herself is on the threshold of life and career as a novelist. The consequences of that are the autobioghraphical signs, which are commented at the beginning of this paper. In the next paragraphs there are described the female hereos of the novel — young women, who are excited with the life and its opportunities, as well as dissappointed with the painful lessons life gives them. This paper is trying to present the femininity “in statu nascendi” and its immaturity, naivety and narcissism. The complicated process of maturation is described with such elements like: looking for love, living in friendship and discovering body and people’s sexuality as well as searching for a right way to live and think. This paper presents a lot of contrasts: naivety and arrogance, innocence and the strength of desire, excitment and the tendency to analyse.
„Ogień i piasek” — o ostatnim okresie życia i twórczości Norwida na podstawie elegii „Na zgon Poezji”
Authors: Grabowski Mateusz
Published: November 2021

The purpose of this article is to analyse one of the leastknown works of the poet — the elegy “Na zgon Poezji”. This is the one of the last three Norwid’s works, and, moreover, the first which is opening the last period of Promethidion’s author writings. Abandoned, condemned to poverty and obscurity poet is experiencing a period of deep collapse, which, however, doesn’t permit him to stay silent. By reference to Norwid’s works, correspondence and biography the author of this paper will try to reconstruct the least known phase of his life – the residence in the shelter of St. Casimir in Ivry.
„Patrzę na zniszczenie, co święci swe dzieło, lecz przecież nic w mym sercu nie poszło na marne” — poetyckie retrospekcje Jana Lechonia
Authors: Urbańska Monika
Published: November 2021

First volume of Jan Lechoń poetry appears in print when he was 13. It surprises its maturity and depth. The young poet reached the common motives of decadent sadness and doubt, but spiritual loneliness, interest of existential themes were not typical for teenager. “Karmazynowy poemat” was received as a literary revelation. Lechoń reaches literary perfection as a young man, so all the adult life he efforts to remain poetic laurel. As a mature creator he glanced at his reflection in the mirror, not only to seek the passage of himself, but also to examine his conscience to settle with the past. At the end of his life, Lechoń was convinced “it is all over”. His poems from this period says about longing for the lost homeland. Inner conflict of poet balancing between memories of his youth and terrifying death wish was his characteristics lifelong feature. Premature maturity and tragic death seemed to be his destiny — each lived year of Lechoń’s life can be considered as a temporary postponement of death heppened to him on New York pavement on tragic Friday afternoon in June 1956.
„Odstąpcie, nie umarła dzieweczka, ale śpi” — życie jest czekaniem na śmierć — z kaznodziejstwa Fabiana Birkowskiego
Authors: Poterała Paulina
Published: November 2021

The aim of this paper is to discuss the influence of the St Augustine thoughts on the sermon “Go away, the girl is not dead, but asleep” from “The Sermons on Sundays Annual Celebrations”. The article focuses on the issue of human dualism (division into soul and body) as well as life dualism (“civitas Dei” and “civitas terrena”).
Potential of Water Hyacinth (Eichhornia crassipes) as Compost and its Effect on Soil and Plant Properties: A Review
Authors: Begum S.L. Rasmiya , Himaya S.M.M.S. , Afreen S.M.M.S.
Published: November 2021

Water hyacinth, the devastating weed grows in water bodies either naturally or as a result of human interference, is considered as threat to environment due to its negative effects on aquatic ecosystems. To alleviate its negative impact utilization of those become as better mean in recent decades. As such, water hyacinth is known to has potential to be utilized as nutrient source via composting, all most all types of composting techniques are applicable in preparation of compost from water hyacinth. Being an organic source, water hyacinth helps build up soil organic matter, in turn play vital role in the enrichment of the soil physical, chemical and biological properties. Aggregation of soil particles, porosity, density, water holding capacity, nutrient availability, cation exchange capacity, pH, soil microorganism are the soil properties reported to improve with water hyacinth compost application. Moreover, water hyacinth compost seems to be far better than the animal manures in improvement of soil properties. As a result, water hyacinth compost shows magnificent effect of plant agronomic growth parameters such as germination percentage, number of leaves, leaf area index, plant height, length of shoot and root, root: shoot ratio, biomass content as well as yield parameters. However, utilization of water hyacinth has few challenges like difficulties in harvesting, chance for heavy metal accumulation, hardness during decomposition, less awareness. Properly managed water hyacinth compost would serve as an alternative for inorganic nutrient sources in future thus indirectly the threat caused by this aquatic weed on environmental would become minimum.
Cryoprotective Activity of Glycerol and Ethylene Glycol: Dynamics with Canine Sperm Integrity
Authors: Kusum Kaushal , Roy Ramakrishna , Sharma Vijay B. , Mishra Raghavendra Prasad , Singh Neha
Published: November 2021

Background: Different cryoprotectants had been used for safe gaurding the post thaw Canine sperm cell motility. Glycerol and ethylene glycol may be used as cryoprotectants. However, scanty reports are available on use of different concentrations of glycerol, ethylene glycol and the combination of glycerol and ethylene glycol as cryoprotectants for canine spermatatozoa. Methods: In present study, the semen samples were collected from 4 different adult spitz male dogs. The diluted semen was divided into four aliquots, Group I: 8% glycerol (control); Group II: 4% glycerol; Group III: 5% ethylene glycol; Group IV: 4% glycerol + 4% ethylene glycol. Result: The result showed that post-thaw sperm motility in canine semen with 5% ethylene glycol was recorded as 36.83±1.26%. For Group I (8% glycerol) and Group II (4% glycerol), the same was 34.25±0.95% and 26.50±0.81%, respectively whereas Group IV (4% glycerol + 4% ethylene glycol) it was 29.25%. However, there was no significant correlationship between abnormal sperm count and live spermatozoa; abnormal sperm count and dead spermatozoa; dead spermatozoa and DNA integrity and in between HOST (hypo-osmotic swelling test) and acrosomal integrity of spermatozoa.
Root Rot Disease Incited by Macrophomina phaseolina in Arid Legumes and their Management: A Review
Authors: Singh Mahabeer , Singh Jitendra , Maurya Shivam , Kumar Sunil , Meena A.K. , Sharma Pinki , Lakhran Lalita
Published: November 2021

Macrophomina phaseolina (Tassi) Goid. is a soil- and seed-borne pathogen that causes charcoal rot and various rots and blights of more than 500 crop species. Dry root rot (DRR) also called as charcoal rot which causes yield loss ranged from 25-48 per cent. The pathogen is necrotroph and infects a wide range of crops. It is observed that mycelium of M. phaseolina in cotyledons, plumule and radicle, in the naturally infected seeds of mungbean and cowpea. The disease symptoms are clearly visible from the time of emergence and can be evaluated at various stages of development of the plant. The mechanical plugging of the xylem vessels by microsclerotia, toxin production, enzymatic action and mechanical pressure during penetration lead to disease development. Management of M. phaseolina aim to reduce the number of sclerotia in soil or to minimize the contact of the inoculum and the host. Soil solarization can be a cost-effective method for management of soil borne diseases. Disease suppression by biocontrol agents such as Trichoderma harzianum, T. viride and Bacillus subtilis are the sustained manifestation of interactions among the plant, the pathogen, the biocontrol agent, the microbial community on and around the plant and the physical environment and considerably inhibited growth of M. phaseolina. Essential oils and plant extracts contain a multitude of bioactive substances against fungi, bacteria and nematodes. It has been reported that neem oil, turmeric and garlic was effective against M. phaseolina in in vitro condition. Chemical control is an effective method when seed treatment and foliar spray of carbendazim, topsin M-70, captan, thiram, mancozeb, copper oxychloride against root rot and leaf blight (Macrophomina phaseolina) topsin M-70, captan, thiram, mancozeb, copper oxychloride against root rot (Macrophomina phaseolina). As non-chemical alternative methods can be time-consuming and less effective against soilborne plant pathogens. Chemical control is an effective method of controlling some soilborne diseases in agricultural crops. Varoius workers are reported compatibility of biocontrol agents with fungicides and found that Carbendazim and biocontrol agents Trichoderma viride, T. harizianum were found effective under in vitro and pot condition.
The efficiency of using digital resources for the development of primary school students' linguodidactic potential
Authors: Makharova Gaukhar , Nurzhanova Sazhila , Adilbayeva Ulzhalgas , Dossanova Albina , Aimagambetova Malika
Published: November 2021

The aim of this research is to evaluate the effects of education given through digital resources on the language didactic potential of students with the views of teachers. 40 primary school teachers who teach 1st-4th grade students in various provinces of Kazakhstan participated in the research. In the research, case study, which is one of the qualitative research methods, was used. The research data were collected through a semi-structured interview form prepared by the researcher in order to get the opinions of the teachers who voluntarily agreed to participate in the research. Research data were analyzed by content analysis technique. As a result of the research, it has been determined that teachers are prone to use technology and partially use digital resources in their lessons. However, teachers stated that they are more open to the use of digital resources if the opportunity is given. In addition, although most of the teachers state that the use of digital resources has no effect on increasing the workload of the teacher, some define it as a workload. Teachers, who believed that it partially increased teacher success, stated that it had a positive effect on student success and student motivation. Research findings reveal that teachers need to receive supportive training on the use of digital resources in education.

Keywords; Digital resources, use of technology in education, linguodidactic potential of students, primary school teachers
Formation of school student’s vocabulary skills through innovative technologies
Authors: Omarovaa Gulnara , Saduakas Gulbanu , Zhumabayeva Aziya , Akzholova Aktoty , Uaisova Gulnar
Published: November 2021

The aim of this research is to determine the attitudes of elementary school 4th graders regarding electronic books developed through innovative technologies in the development of vocabulary. Qualitative research methods were used in accordance with the purpose of the research. The data of the research were collected by the semi-structured interview form developed by the researcher. The study involved 20 elementary school 4th graders studying in Almaty, Kazakhstan in the 2019-2020 academic year. As a result of the research, it was concluded that students have a moderate tendency to read electronic books and have a tendency to prefer electronic books as much as printed books. In addition, students found electronic books to be easily accessible, easy to learn and advantageous with their ability to be easy to learn, while they found themselves disadvantaged in terms of easy concentration, eye strain and technology addiction. Based on the results of the research, it is recommended to improve electronic books through innovative technologies and to carry out studies on increasing the use of electronic books by students.
Keywords: Electronic book, innovative technologies, student feedback, technology-based learning
Teachers' views on the level of cultural heritage knowledge that can be improved through innovative technologies
Authors: Zhabykbayeva Dinara , Sanay Gaukhar , Bekish Azamat , Zhylkybekova Gulbira , Kasymbekov Zhakypbek
Published: November 2021

The purpose of this research is to determine primary school students' perceptions of cultural heritage and to evaluate student and teacher views on the level of cultural heritage knowledge that can be improved through innovative technologies. The research was carried out with 20 primary school students and 10 primary school teachers who were educated in the city of Almaty, Kazakhstan in the 2020-2021 academic year. The research was designed in the case study pattern, which is one of the qualitative research methods. The data collection tools of the research were developed by the researcher. Semi-structured student interview form and semi-structured teacher interview form were used to collect data in the research. The analysis of the data was carried out using the content analysis method. The results of the research reveal that the students have a good grasp of some concepts related to the definition of cultural heritage and they partially know the tangible cultural heritage and intangible cultural heritage items. While the teachers did not find the cultural heritage education sufficient, they stated that an education through innovative technologies would increase the level of student knowledge and made suggestions regarding this. Research findings reveal the necessity of using innovative technologies in cultural heritage education and accordingly the need for new regulations in education programs.

Keywords; Cultural heritage, Innovative technologies, Cultural heritage education, Student knowledge level.
El esquivo perdón
Authors: Prada Manuel Alejandro , Ruiz Alexander
Published: November 2021

En el artículo se hace una exploración preliminar del sentido y del valor otorgado al perdón por parte de reconocidos pensadores contemporáneos como Vladimir Jankélévitch, Jacques Derrida y Paul Ricœur. Se analizan estudios empíricos sobre el perdón realizados en Iberoamérica y Colombia, en contextos situados desde la psicología social, las ciencias políticas, la antropología y la educación. Luego, se concluye que el perdón trasciende la esfera íntima tanto del infractor como del agredido y está relacionado con el daño moral o el menoscabo de la dignidad de quienes sufren dicho daño, lo que es particularmente notorio en situaciones marcadas por la impunidad en contextos de violencia política. Además, se resalta la escasez de estudios sobre el perdón en el campo de la educación y la relevancia que tiene preguntarse si es posible enseñar a perdonar o si el perdón ha de tener lugar en la escuela únicamente como un horizonte de comprensión de la formación moral y política.
Las optimizaciones en los contratos de asociación público privada a la luz de la normativa vigente: la regulación incoherente
Authors:   , Li Ojeda Jaime Alfieri
Published: November 2021

Por medio del Decreto Supremo Nº 410-2015-EF, el cual aprobó el Reglamento del Decreto Legislativo Nº 1224, Decreto Legislativo que regula la Promoción de la Inversión Privada mediante Asociaciones Público-Privadas (en adelante, las APP’s) y Proyectos en Activos (actualmente derogado) se incorporó a las optimizaciones en el marco normativo nacional referido a la ejecución de contrato de APP. El mencionado mecanismo ha vuelto a ser considerado dentro del Decreto Legislativo N° 1362 y su reglamento aprobado por Decreto Supremo N° 240-2018-EF. Así, las optimizaciones se incorporaron como un mecanismo para realizar cambios a determinadas obligaciones establecidas en los contratos de APP. No obstante, se ha apreciado que dichas optimizaciones presentan una regulación confusa, la cual ha generado confusiones y discordancias respecto de en su correcta ejecución y, por ende, el desarrollo de las obligaciones establecidas en los contratos; ello se aprecia por ejemplo en el caso específico del Contrato de Concesión de la Línea 2 del Metro de Lima. Por lo tanto, por medio del presente trabajo de investigación se planteará una propuesta de regulación de las optimizaciones, la cual tiene por finalidad que estas se vuelvan una herramienta que permita mejorar su aplicación en los contratos de APP.
El proceso de selección y reclutamiento de personal y su impacto en la Tasa de Rotación de Personal en el Ministerio Público del Distrito Fiscal de Lima Sur durante los años 2015 -2018
Authors:   , Aguilar Medina Raphael Steward
Published: November 2021

La presente investigación titulada “El Proceso de selección y reclutamiento de personal y su impacto en la Tasa de Rotación de Personal en el Ministerio Público del Distrito Fiscal de Lima Sur durante los años 2015-2018” tiene por objetivo revisar el proceso de selección y reclutamiento de personal y proponer mejoras que impacten en la disminución de tasas de rotación en el Ministerio Público del Distrito Fiscal de Lima Sur. Para lograr dicho cometido se ha planteado una investigación de enfoque cualitativo, el cual se avocó al análisis y estudio de la entrevista realizada a experto, encuesta a los servidores y ex servidores de la institución que evidencien el modo en que se procede la selección y reclutamiento de personal en el Ministerio Público del Distrito Fiscal de Lima Sur. Además se ha analizado y estudiado el proceso de selección y reclutamiento de diversas organizaciones públicas y de empresas privadas cuyas buenas prácticas podrían coadyuvar en mejorar el proceso de reclutamiento y selección en el Ministerio Público de Lima Sur. Luego del cual, se presentan propuestas y recomendaciones a fin de que el Ministerio Público implementen mejoras en su sistema de selección y reclutamiento y logre un impacto positivo disminuyendo la tasa de rotación de personal en lo que respecta a renuncias.
Museo Aeronáutico Interactivo sobre la historia de la Fuerza Aérea del Perú
Authors:   , Klepatzky Portocarrero Katherine Pamela
Published: November 2021

El presente proyecto aporta una investigación de un Museo Aeronáutico Interactivo sobre la historia de la Fuerza Aérea del Perú, manteniendo y reciclando lo que fue en su momento fue el “Alma Mater” de la Institución, el Pabellón Central de Cadetes de la Escuela de Oficiales e implementando nuevos espacios. El proyecto se dará en la Base Aérea de Las Palmas, frente a su Plaza de Armas, en el distrito limeño de Santiago de Surco. En primer lugar, se analizarán las problemáticas y los objetivos de la tipología escogida, se estudiará el funcionamiento de los museos aeronáuticos existentes en el Perú, con la finalidad de obtener un mejor resultado al final del proyecto. También se realizará una investigación para entender como fue evolucionando esta clase de museos, se hará comparación con proyectos referenciales que se han ido construyendo a lo largo del tiempo; tanto, dentro del país como en el exterior. Finalmente, con todo este análisis elaborado se busca obtener toda la información necesaria para elaborar el primer Museo Aeronáutico Interactivo donde los visitantes puedan disfrutar, aprender y difundir toda la información captada dentro de la infraestructura a través de nuevos métodos de exhibición y demostración. Dicho Museo llenará un vacío cultural, que incentivará a los ciudadanos a conocer más sobre la historia, valores y evolución de la aviación y la Fuerza Aérea del Perú, así como los grandes héroes que dieron su vida para que nuestro país saliera adelante; así como su compromiso con nuestra nación y sus valores.
Los festivales musicales en el Perú como medio de difusión de nuevas propuestas del género tropical entre 2014 y 2019
Authors:   , Alarcón Figueroa Adrián Enrique
Published: November 2021

La presente investigación aborda el proceso y desarrollo de los festivales musicales en el Perú que presentan propuestas del género tropical en su programación. Dentro de estas propuestas tropicales, se busca dar mayor énfasis a la inclusión de nuevas agrupaciones provenientes de la fusión de cumbia con rock, que son agrupaciones de una escena formada desde fines del 2000 y que actualmente están trabajando en el constante crecimiento de su marca, público, puesta en escena, marketing, entre otros aspectos. El objetivo general de esta investigación es averiguar el nivel de difusión que genera la participación de estas nuevas agrupaciones en festivales nacionales. Para ello, se mostrará un marco teórico y conceptual del festival de música y el desarrollo de conciertos en Perú de 2007 hasta 2019, mostrando que existe un aumento en la oferta de festivales musicales entre 2014 y 2019. Asimismo, se realizará un breve repaso del desarrollo de las agrupaciones del género tropical en el Perú hasta llegar a las agrupaciones consideradas en esta investigación como las nuevas propuestas musicales del género tropical; es importante mencionar que se abordará su formación, comunicación, estrategias de marketing, análisis musical, puesta en escena y su participación en festivales nacionales. Posterior a esto, se realiza un acercamiento a la relación entre festivales y agrupaciones proponiendo, por un lado, conocer qué cosas están buscando los programadores de festivales para decidir que agrupaciones convocarán y, por otro lado, saber si las agrupaciones están dispuestas o pueden acercarse a cumplir estos requisitos; para darle mayor profundidad a este tema se presenta el caso de cuatro agrupaciones tropicales. Finalmente, se presenta un análisis del resultado de una encuesta realizada a personas que asisten a festivales de música para conocer su percepción como público respecto a los festivales y a las nuevas propuestas del género tropical.
PERAN PEMERINTAH KOTA SURABAYA DALAM PENGATURAN TRANSPORTASI PUBLIK KOTA SURABAYA: STUDI PERKOTAAN PROGRAM “SUROBOYO BUS”
Authors: Winaryo M. Bayu , Martanto Ucu
Published: November 2021

The research focuses on the role of government institutions related to regulating public transportation in the city of Surabaya. Transportation is one sector which influences the economic growth of a city, the potential to be utilized as a commodity used in obtaining sources of power by some parties. Because in the practice of management, how a ruling regime is able to regulate, control and determine the direction of policy that will influence various efforts taken by the government to encourage economic growth from the region so as to be able to "turn on industrial machinery in its territory" and create new economic growth centers. Suroboyo Bus is also a manifestation of ongoing democracy in the city of Surabaya. In this study, we will explain several problems, first discussing the institutions involved in the process of forming a political decision related to the management of Suroboyo Bus, secondly about the interests involved in the political decision, the three relations that will emerge during the process. In this study it is known that the mayor is the institution that most determines the direction of policy that will be taken in the transportation sector in the city of Surabaya.
Valences of Financial Reporting According to IFRS. Up-to-Date Challenges for Financial Auditors
Authors:   The Bucharest University of Economic Studies, Romania, Manolescu Maria , Petre Georgeta ,   financial auditor, Lazar Alexandra ,   financial auditor
Published: November 2021

Through this paper, the authors want to mark the centenary of the accounting profession in our country (1921-2021). They aim to analyze the evolution of financial reporting, at the national level, in the last three decades, parallel to the natural development of the accounting profession and to bring into the spotlights: – how developments at the national level have kept pace with the ever-changing European and international financial reporting requirements; – the current challenges for the accounting profession in general and financial auditors, in particular, generated by the frequent and particularly complex changes of international standards in the field, changes generated precisely by the need to strengthen the quality of the information provided by financial reporting; – the natural steps to be taken to strengthen professional cooperation and collaboration within and in the interest of the accounting profession, to respond effectively to the expectations of all stakeholders in the development of financial reporting.
Factors Influencing KAM Reporting: A Structured Literature Review
Authors:   Babes-Bolyai University, FSEGA, Cluj-Napoca, Porumbacean Teodora , Tiron-Tudor Adriana ,   Babes-Bolyai University, FSEGA, Cluj-Napoca
Published: November 2021

The disclosure of KAMs contribute to the increase of financial-reporting quality, the value of the audit report and implicit interest in it. Moreover, KAM’s disclosure has a positive influence over the expectation gap between the auditors and other users of the audit report and financial statements. This study aims to identify relevant drivers influencing the Key Audit Matters (KAMs) disclosed in the audit report, based on a review of the articles published in top accounting journals. Our results reveal the fact that the audited company itself especially influences the disclosure of the KAMs, emphasizing the size of the company, the complexity of the business, the applicable regulation of the industry in which the company operates, all of which impact the overall client-risk level. Other relevant factors are the accounting standards with which the company must comply and on which it must report, the audit company (‘Big Four’ or not) and the audited company’s location.
STABILIZATION OF LEACHATE IN AGGREGATES MADE WITH PLASTIC FROM WEEE
Authors: Cappelletti Ariel , Peisino Lucas , Gaggino Rosana , Uberman Paula Marina , Colman Lucas , Kreiker Jerónimo
Published: November 2021

A recycled plastic aggregate (RPA) was developed using the core-shell strategy, where the core is the plastic fraction of Waste of Electrical and Electronic Equipment (WEEE) and a cement matrix with stabilizing additives acts as the shell. The amount of brominated flame retardant (mainly tetrabromobisphenol-A) leached in curing water of RPAs was quantified using extraction with an organic solvent and gas chromatography methods (CG-FID). A clear relationship can be established between the characteristics of the stabilizing additive used and the amount of tetrabromobisphenol-A and bisphenol-A leached. The additive used was activated carbon, which in a manufacture scale may be provided by different suppliers with different mesoporous characteristics, which can be easily determined by the iodine number. The analysis proposed can be an effective way to determine if a particular activated carbon can be used as stabilizing additive in the production of RPAs with the developed technology.
Arabidopsis PII Proteins Form Characteristic Foci in Chloroplasts Indicating Novel Properties in Protein Interaction and Degradation
Authors: Krieger Natalie , Pastryk Kai-Florian , Forchhammer Karl , Kolukisaoglu Üner
Published: November 2021

The PII protein is an evolutionary highly conserved regulatory protein from bacteria to higher plants. In bacteria it modulates the activity of several enzymes, transporters and regulatory factors by interacting with them and thereby regulating important metabolic hubs like carbon/nitrogen homeostasis. More than two decades ago the PII protein was characterized for the first time in plants, but its physiological role is still not sufficiently resolved. To gain more insights into the function of this protein, we investigated the interaction behaviour of AtPII with candidate proteins by BiFC and FRET/FLIM in planta and with GFP/RFP traps in vitro. In the course of these studies we found that AtPII interacts in chloroplasts with itself as well as with known interactors like NAGK in dot-like aggregates, which we named PII foci. In these novel protein aggregates AtPII interacts also with yet unknown partners, which are known to be involved in plastidic protein degradation. Further studies revealed that the C-terminal part of AtPII is crucial for the formation of PII foci. Altogether, the presented results indicate a novel mode of interaction for PII proteins with other proteins in plants, which may be a new starting point for the elucidation of physiological functions of PII proteins in plants.
THE IMPACT OF KEY AUDIT MATTERS DISCLOSURE ON COMMUNICATIVE VALUE OF THE AUDITOR’S REPORT: A SYSTEMATIC LITERATURE REVIEW
Authors:   Center for Finance Professions Supervisory, Yoga Budhi , Dinarjito Agung ,   Polytechnic of State Finance STAN
Published: November 2021

This research aims to discuss whether the disclosure of key audit matters (KAM) increases the communicative value of the auditor’s report. It also examines factors that need to be considered related to KAM disclosure. It is carried out in connection with the issuance of the Exposure Draft of Indonesia Audit Standard (AS) 701 on ”Pengomunikasian Hal Audit Utama dalam Laporan Auditor Independen” which was adopted from the International Standard on Auditing 701. In Indonesia, no research was found yet related to this topic. By conducting a systematic literature review of the latest articles from 2012 to 2021, this study found that KAM disclosure increases the communicative value of the auditor’s report, which is useful for report users in their decision-making. This study also informed specific areas that were often disclosed as KAM and provided information related to the factors that can decrease the communicative value of KAM disclosure. The results support the plan of AS 701 implementation in Indonesia because it will increase the communicative value of the auditor’s report. This study will be of interest to auditors in preparing the implementation of AS 701, report users in understanding KAM disclosure, and regulators as initial infor­mation regarding KAM disclosure to support their duties when AS 701 has been effectively implemented in Indonesia.
Industry preferences for foreign patenting of Russian innovation enterprises
Authors:   Russian State Academy of Intellectual Property (RSAIP), Kitaisky Vladimir , Revinsky Grigory ,   LLC «VKO-Intellect», Revinsky Oleg ,   Russian State Academy of Intellectual Property (RSAIP), Shvedova Vera ,   Russian State Academy of Intellectual Property (RSAIP)
Published: November 2021

Our paper is devoted to the science-research work carried out in the Russian State Academy of Intellectual Property (RSAIP) for revealing the role of foreign patenting for development of export of high-technology goods made by Russian manufacturers, first of all by small and medium-sized innovation enterprises. The results of study the patent documents indicating preferences of Russian innovation enterprises in foreign patenting of their new developments are presented in this paper. Preliminary conclusions on preferences in choice of countries for patenting and fields where innovations are made have been given. It is well known that the development of a competitive economy depends on the innovative activity of enterprises in the market. Understanding of terminology of innovation and invention opens up their economic and legal essence. A special and basic characteristic of innovation is creativity. In the Japanese business and management system, creativity is a production slogan and an inspiring idea, since creativity generates a person’s desire to improve in work through intelligence. A product that is new on a global level is recognized as an invention and is regulated by patent law. The state of the art for the invention includes all information that became publicly available in the world before the date of applying with the State Department of intellectual property. The aim of our study is to analyze the economic aspect of patenting made by the innovative companies in the world with attention to Russia, taking into account the role of innovation infrastructure. Modern concepts of innovative development of economic systems at various levels (state, region, industry, business entity) increasingly focus on the need for new forms of integration of scientific, industrial, commercial, and other resources to increase competitiveness. Domestic and foreign researchers, government, and business representatives pay attention to clusters as a promising form of integration and practical implementation of the idea of Public-Private Partnership for Innovative Industrial Development. The cluster approach allows combining the advantages of specialization, integration, and cooperation in increasing the competitiveness of business entities in a higher-level organizational and economic system (regional, industry cluster) by consolidating production, financial, intellectual, and managerial resources. Clustering of the innovation system in industry allows transition from supporting individual production enterprises or organizations that carry out scientific research to stimulating the development of relationships between them and other subjects of commercialization of scientific research.
Analysis of the financing activities of European football leagues
Authors:   G. V. Plekhanov Russian University of Economics (PRUE), Litvishko Oleg , Aliev Ayaz ,   G. V. Plekhanov Russian University of Economics (PRUE), Veynberg Roman ,   G. V. Plekhanov Russian University of Economics (PRUE), Kokoulina Olga ,   G. V. Plekhanov Russian University of Economics (PRUE), Farzaliev Javid ,   G. V. Plekhanov Russian University of Economics (PRUE), Gyömörei Tamás ,   Széchenyi István University (SZE)
Published: November 2021

In a market economy, effective financial management is one of the most important aspects of the functioning of any company, which plays a connecting role between various areas of its activities and determines the company’s position on the market, its competitiveness, prospects for sustainable development and cost growth. In this context, the assessment of the economic efficiency of sports organizations is also relevant, due to the high social significance of the sports industry and its huge popularity among the population. The study selected leagues that use different approaches to the formation and distribution of financial resources in their activities. Thus, the subject of this research is the existing mechanisms for financing the activities of sports subjects. The comparative report of UEFA on club licensing for pre-COVID-19 period was used as an analytical basis for the study. The results obtained during the study showed that with an effective approach to the process of managing financial and economic activities, the professional sports industry can be considered as a promising tool that can generate a significant material and non-material effect on various spheres of public activity, which affects the dynamic economic growth of the industry, as evidenced, in particular, by the performance index of the football leagues of Europe calculated in the work, showing the stable growth of the industry in the pre-COVID-19 period.
Characteristics and Prognosis of Antibody Non-Responders with COVID-19
Authors: Ding JunYu , Liu Changxin , Wang Zhao , Guo Hua , Zhang Kan , Ma Lin , Wang Bo , Zhao Huijun , Song ManYa , Guan Xizhou
Published: November 2021

Background：The coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been spreading globally. The information regarding the characteristics and prognosis of antibody non-responders with COVID-19 is scarce.Method: In this retrospective, single-center study, we included all the patients with confirmed COVID-19 using real-time reverse transcriptase-polymerase chain reaction (RT-PCR) admitted to the Fire God Mountain hospital from February 3, 2020, to April 14, 2020. A total of 1921 patients were divided into the antibody-negative group (n=94) and antibody-positive group (n=1827), and the 1:1 propensity score matching (PSM) was used to match two groups.Results: In the antibody negative group, 40 patients (42.6%) were male, 54 patients (57.4%) were female, and 49 patients (52.1%) were older than 65 years old. Cough was the most common symptoms in the antibody negative group. White blood cell counts (WBC) 6.6×109/L [5.0, 9.1], Neutrophils 4.3×109/L [3.1, 6.6], C-reactive protein 7.3 mg/L [1.3, 49.0], Procalcitonin (PCT) 0.1 ng/mL [0.0, 0.2], Interleukin-6 (IL-6) 64.2 [1.5, 28.7], Lactate dehydrogenase (LDH) 193.8 U/L [154.9,260.6], Creatine kinase 60.5 U/L [40.5, 103.7], Creatine kinase isoenzyme 10.3 ng/mL [8.2, 14.5], Urea nitrogen 5.3 mmol/L [4.0, 8.7] and Creatinine 77.7 μmol/L [60.6, 98.7] were significantly higher in antibody negative patients than in antibody positive group (P<0.005). The days of nucleic acid negative conversion in the antibody negative group was shorter than that in the antibody positive group (P < 0.001). Meanwhile, the hospitalization time of antibody negative patients was shorter than that of antibody positive patients (8.0 [6.0, 10.0] VS 13.0 [8.2, 23.0], P < 0.001).Conclusion: Some COVID-19 patients without specific antibodies had mild symptoms, but the inflammatory reaction caused by innate clinical immunity was more intense than those with antibodies, and the virus was cleared faster. The production of specific antibodies was unnecessary for SARS-CoV-2 clearance, and non-specific immune responses played an essential role in virus clearance.
Heuristic Approaches With Reinforced Parameter Tuning for the Car Sequencing Problems With Block Batches
Authors: Yu Yingjie , Lu Xiaochun , Zhao Tao , Cheng Minjiao , Liu Lin , Wei Wenchao
Published: November 2021

Motivated by the practical supply chain management of the automobile industry, we study the car sequencing problem (CSP) that minimize the conflicts arising from scheduling cars into an assembly line. The CSP is a well established problem, subject to the paint batching constraints to reduce the the costs for color changes and capacity constraints in the assembly shop to level the usage of the options. However, the existing approaches to this problem do not take into account the block batches, which desires a consecutive production batch of cars requiring a certain option. This requirement often occurs when specialized labor time window is short in the customized car production scenario, and renders additional complexities to the traditional car sequencing problem. In this paper, we propose a novel model to deals with these constraints and simultaneously generate the sequencing and replenishment decisions. In addition to our model formulation, we develop two math-heuristic approaches to solve the propose large-scale car sequencing problem. The selected heuristics are based on relax-and-fix procedures, fix-and-optimize procedures and variable neighborhood search. To solve the large-sized instances (commercial solvers, i.e., Cplex, cannot provide a feasible solution within 1 hour), we design and implement a reinforced parameter tuning mechanism to dynamically select the parameter values, so as to speed up the search process. The proposed models and heuristics are tested on compatible instances from the benchmark in the literature (CSPLib), as well as large-sized instances generated from real-world cases. We report on extensive computational experiments, and provide basic managerial insights into the planning process.
Abandonment of Patients in Emergency Department of Tertiary Care Hospital of Eastern Nepal- an Observational Study
Authors: CHAUDHARY RITESH , Bhandari Rabin , Giri Saroj , Shrivastav Vijay , Bhandari Rupak
Published: November 2021

Background

Patient abandonment in the emergency department has been reported in various parts of the world although the implications and social circumstances may vary in context to its definition. The current study intends to review the characteristics of twenty- four (24) abandoned patients in the emergency department of tertiary care hospital of Eastern Nepal.
Methods

This was a prospective observational study conducted among all abandoned patients presenting to tertiary care hospital in eastern Nepal from July 2018 to July 2020.
Results

Twenty four (24) patients were enrolled in the study. 22 (91.7%) were male and 2 (8.3%) were female with a mean age of 43.2 ± 14.4SD. The median length of stay (LOS) was 72 (Q1, Q3, 23.5, 960) hours in the emergency department. Seven, 7 (43.75%) cases of mortality were due to medical illness, 4 (25%) cases of mortality were due to surgical illness and 5 (31.25%) cases of mortality were with undifferentiated presentations (p= 0.012). 15 of 24 (62.5%) patients over 40 years of age experienced a longer LOS (p = 0.34) and (75%) 12 of 16 have a higher mortality than younger patients (p= 0.30). More than (USD) $50 was invested in an abandoned case that was taken care of by NGOs. 6 (25%) of abandoned patients were taken care of by other centers like NGOs and welfare centers.
Conclusions

Abandoned patients in the middle-aged adults with medical comorbidity experienced longer hospital stays and as an indicator of mortality. Financial disparities were observed among abandoned patients taken care of by charitable organizations and tertiary care hospital.
Genetic Mapping of Powdery Mildew Resistance Genes in Wheat Landrace ‘Guizi 1’ Using Genotyping-By-Sequencing
Authors: Li Luhua , Yang Xicui , Wang Zhongni , Ren Mingjian , An Chang , Zhu Susong , Xu Ruhong
Published: November 2021

Wheat powdery mildew (Pm), caused by Blumeria graminis f. sp. tritici (Bgt), is a destructive disease of wheat (Triticum aestivum L.) worldwide that causes severe yield losses. Resistant wheat cultivars easily lose effective resistance against newly emerged Bgt strains; therefore, identifying new resistance genes is necessary for breeding resistant cultivars. ‘Guizi 1’ is a Chinese wheat cultivar with effective moderate and stable resistance against powdery mildew. A genetic analysis indicated that powdery mildew resistance in ‘Guizi 1’ was controlled by a single dominant gene, designated PmGZ1. In total, 110 F2 individual plants and the 2 parents were used for genotyping-by-sequencing, which produced 23,134 high-quality single-nucleotide polymorphisms (SNPs). The SNP distributions on the 21 chromosomes ranged from 134 on chromosome 6D to 6,288 on chromosome 3B. Chromosome 6A has 1,866 SNPs, among which 16 are located in a physical region between positions 307,802,221 and 309,885,836 in an approximate 2.3-cM region, which possessed the greatest SNP density. The average map distance between SNP markers was 0.1 cM. A quantitative trait locus with a significant epistatic effect on powdery mildew resistance was mapped to Chromosome 6A. The LOD value of PmGZ1 reached 34.8, and PmGZ1 was located within the confidence interval marked by chr6a-307802221 and chr6a-309885836. The phenotypic variance explained by PmGZ1 was 74.7%. Four candidate genes (two each encoding TaAP2-A and actin proteins) were annotated as resistance genes. The present results provide valuable information for wheat genetic improvement, quantitative trait loci fine mapping, and candidate gene validation.
Repopulating Kupffer Cells Originate Directly from Hematopoietic Stem Cells
Authors: Fan Xu , Lu Pei , Cui Xianghua , Wu Peng , Lin Weiran , Zhang Dong , Yuan Shunzong , Liu Bing , Chen Fangyan , You Hong , Wei Handong , He Fuchu , Jia Jidong , Jiang Ying
Published: November 2021

Kupffer cells (KCs) originate from yolk sac progenitors before birth, but the origin of repopulating KCs in adult remains unclear. In current study, we firstly traced the fate of preexisting KCs and that of monocytic cells with tissue-resident macrophage-specific and monocytic cell-specific fate mapping mouse models, respectively, and found no evidences that repopulating KCs originate from preexisting KCs or MOs. Secondly, we performed genetic lineage tracing to determine the type of progenitor cells involved in response to KC depletion in mice, and found that in response to KC depletion, hematopoietic stem cells (HSCs) proliferated in the bone marrow, mobilized into the blood, adoptively transferred into the liver and differentiated into KCs. Finally, we traced the fate of HSCs in a HSC-specific fate-mapping mouse model, in context of chronic liver inflammation induced by repeated carbon tetrachloride treatment, and confirmed that repopulating KCs originated directly from HSCs. Taken together, these findings provided in vivo fate-mapping evidences that repopulating KCs originate directly from hematopoietic stem cells, which present a completely novel understanding of the cellular origin of repopulating Kupffer Cells and shedding light on the divergent roles of KCs in liver homeostasis and diseases.
Availability of CT on island medical facilities: Association with mortality in patients evacuated via long-distance air medical transport
Authors: Ishihata Ayaka , Nakajima Mikio , Ono Sachiko , Kaszynski Richard H , Takane Ryo , Shirokawa Masamitsu , Otawara Masayuki , Nakano Tomotsugu , Goto Hideaki
Published: November 2021

Background

To examine the association between availability of computed tomography (CT) and severity-of-disease/mortality in patients evacuated via long-distance emergency air medical transport from island medical facilities.
Methods

We retrospectively and consecutively enrolled patients transferred via rotary- or fixed-wing aircraft from island medical facilities to a designated emergency medical center in Tokyo, Japan between 2010 and 2020. Airlifted patients were divided into two groups, depending on the availability of CTs on the island facilities in which they were transported from. The outcomes were severity-of-disease after air medical transport and in-hospital mortality. We examined the association between these outcomes and the availability of CTs on each island facility.
Results

Eligible patients (n=1,880) were categorized into the CT (n=1,744) or non-CT group (n=136). After adjusting for age, sex, diagnostic category and flight time, the CT group was significantly associated with greater severity of disease (coefficient, 1.30; 95% confidence interval, 0.13–2.47). In contrast, significant reductions in mortality were not documented in the CT group.
Conclusion

While the availability of CTs was significantly associated with greater severity of disease, CT availability did not significantly impact mortality in patients transferred from island medical facilities.