bluuebunny/crossref_metadata_2025 huggingface dataset:
ANALYTICAL STUDY OF VARIOUS ECONOMICS AND SOCIAL PROBLEMS IN THE ERA OF GLOBALIZATION AND COVID-19
Authors: agarwal Amit , Singh Abhishek Kumar
Published: March 2022

In the era of globalization, the business of goods and services has become international rather than at the national level. Citizens of one country are moving freely for employment in another country with certain restrictions. Due to globalization, the spread of the Covid-19 epidemic took place on a global scale. Globalization has had positive and negative effects on the economy of any country. Different types of problems have arisen in different countries, the main reason for them is considered to be globalization and the Covid-19 epidemic. Data were collected and analyzed from respondents about problems like unemployment, poverty and economic and social inequalities, inflation or increase in the rate of inflation, industrial sickness, low per capita income, social structure, language, and cultural change, etc. presented through paper. When we talk about India, 65 to 70 percent of the country's economy is unorganized, so people like street vendors and auto drivers have been affected the most by the lockdown. It will be a challenge for them to get their business back up. Hotel, tourism, logistics, and aviation industries have been badly hit due to the lockdown. The poor and downtrodden have been directly affected during the lockdown. Although the central government and many state governments have also offered to help this section in many ways, it will not be so easy to recover directly from this effect.
The Effect of Vitamin D treatment on COVID 19- Patients, an Inverted Propensity Score Weighting (IPSW), and Inverted Probability of Treatment Weighting (IPTW) Analyzed Study
Authors: Wadi Al Ramahi Jamal , Hasan Nour , Matar Amal , Maher Al-Ali Ma'en , Abdulhadi Lara , Abu Kaf Dania , Saadeh Waseem , Hamdan Nour , AbuKhalaf Hassan , Gharaibeh Mohamed , Hamadallah Hanadi , Bader Ala'a , Atout Mohammad , Moh. Mar’I Sae’ed , Alhamed Tamer
Published: March 2022

Background
Vitamin D3 (1,25(OH)2 cholecalciferol) as a treatment for COVID 19 patients is being disputed, and a clear clinical benefit is not being confirmed.
Methods
A retrospective evaluation for COVID-19 patients who were treated with various cumulative doses of vitamin D. Data was extracted from the COVID-19 database, it included patients admitted to three hospitals in Amman, Jordan. Characteristics of patients were tabulated and compared for all-cohort, and propensity score index (PSI) adjustment, The comparison was based on two vitamin D strata ((≤ 149,000 i.u. and > 150,000 i.u.). Logistic regression analysis was utilized to predict recovery, the need for oxygen, and all-cause mortality for all-cohort, IPSW, and IPTW patients, based on vitamin D cumulative doses during their hospital stay.
Results
            1131 all-cohort and 768 PSI-adjusted patients were recruited. Except for antibiotics and antivirals, all other characteristics were balanced (P = NS). There were 1017 patients on vitamin D, 847 received cumulative ≤ 149,000 i.u., and 170 patients received cumulative dose ≥ 150,000 i.u. (Range 1000 – 385000). It was demonstrated that escalating cumulative doses of vitamin D did not contribute to the assessed outcomes; all-cohort patients (OR = 1.000, 95% C.I. 1.000 to 1.000), IPSW (OR = 1.000, 95% C.I. 1.000 to 1.000), and the IPTW (OR = 1.000, 95% C.I. 1.000 to 1.000).
Conclusion
            In our patients’ cohorts, we could not demonstrate a beneficial effect for vitamin D therapy in COVID-19 patients for recovery, the need for home oxygen, and all-cause mortality, by hospital discharge.
THE EFFECT OF SELECTED MARKETING ACTIVITIES AND PROMOTIONS ON THE CONSUMERS BUYING BEHAVIOR
Authors: Alhalalmeh Mohammad , Alkhawaldah Reyad Abdallah , Mohammad Anber , Al-Quran Ali , Hijjawi Ghufran , Al-Hawary Sulieman
Published: March 2022

The core purpose of this study is to determine the impact of electronics marketing (word of mouth), perceived value, and social networking on customer buying behaviour through customer trust in the context of cosmetic industry of Jordan. To accomplish the main research objective, the study has followed SEM technique for analysing collected data. For data collection, the use of survey questionnaire has been made, in which data was collected from total 223 respondents. The results of this study confirm the significant impact of perceived value on customer trust and customer buying behaviour, whereas electronic marketing (word of mouth) was found to have insignificant impact on both customers buying behaviour and customer trust. Findings also revealed the significant impact of social networking networks on customer buying behaviour. However, its impact on customer trust was insignificant. With respect to mediating effect, customer trust significantly mediates the association between perceived value and customer buying behaviour.
H2 Cooling and Gravitational Collapse of Supersonically Induced Gas Objects
Authors: Nakazato Yurina , Chiaki Gen , Yoshida Naoki , Naoz Smadar , Lake William , Chiou Yeou S.
Published: March 2022

We study the formation and gravitational collapse of supersonically induced gas objects (SIGOs) in the early universe. We run cosmological hydrodynamics simulations of SIGOs, including relative streaming motions between baryons and dark matter. Our simulations also follow nonequilibrium chemistry and molecular hydrogen cooling in primordial gas clouds. A number of SIGOs are formed in the run with fast-streaming motions of 2 times the rms of the cosmological velocity fluctuations. We identify a particular gas cloud that condensates by H2 cooling without being hosted by a dark matter halo. The SIGO remains outside the virial radius of its closest halo, and it becomes Jeans unstable when the central gas-particle density reaches ∼100 cm−3 with a temperature of ∼200 K. The corresponding Jeans mass is ∼105
M
⊙, and thus the formation of primordial stars or a star cluster is expected in the SIGO.
Le répertoire narratif non romanesque publié en Normandie
Authors: Blom Helwi
Published: March 2022

La liste des titres faisant partie du catalogue des éditeurs de la Bibliothèque bleue de Normandie ( xvii e - xix e  siècles) comprend un nombre impressionnant de titres qui, sans être des romans, relèvent de la fiction narrative. Le présent article se propose d’explorer cet important ensemble largement sous-étudié, en faisant l’inventaire des éditions, en dressant le profil des textes en question et en étudiant les stratégies éditoriales spécifiques dont ils ont fait l’objet au sein de la « collection » normande.
Les fenêtres de Wajdi Mouawad
Authors: Berton Jacques
Published: March 2022

À partir d’un fragment de texte, l’auteur met en lien les propos du metteur en scène : Wajdi Mouawad sur le théâtre, avec les questionnements spécifiques à la posture professionnelle et aux enjeux de l’observation. Celle-ci, menée par un sujet, adopte toujours un point de vue et ce n’est que lorsqu’elle est confrontée à d’autres points de vue qu’elle a quelque chance de devenir un peu plus objective. Métisser les sciences humaines, la littérature, le théâtre s’inscrit pleinement dans une approche complexe où l’objectif serait de multiplier « les fenêtres » comme des ouvertures sur le monde.
La lecture des livres et des écritures ordinaires-mineures en éducation spécialisée. Lire c’est agir !
Authors: Contini Jean-Christophe
Published: March 2022

Si la lecture d’ouvrages de référence est une dimension fondamentale dans la formation professionnelle en éducation spécialisée, on oublie bien souvent qu’elle constitue également une activité quotidienne dans le cadre de l’exercice du métier, comme dans le cas de l’écriture et de la lecture du cahier de bord. Le métier d’éducateur pourrait être dès lors considéré comme un « métier théorique », car on ne verrait et entendrait dans une relation que ce qu’on serait en mesure de comprendre intellectuellement, l’écriture étant toujours l’inscription d’une lecture. Mais de quelle(s) lecture(s) est-il ici question ?
L’émancipation du sujet en formation. La professionnalisation passe par l’identification
Authors: Goralczyk Frédérique
Published: March 2022

Les éducateurs éprouvent des difficultés à articuler les logiques contradictoires de la relation éducative, dans une quête de légitimité exacerbée par le manque de reconnaissance dont ils souffrent. Cette difficulté d’articulation est en partie due aux représentations qu’ont les éducateurs de ces deux logiques et notamment des normes qui s’y rattachent. La conjonction de ces facteurs augmente la souffrance au travail, générant une dérive rationalisante de l’action sociale ainsi qu’une forme de toute-puissance des éducateurs sur l’usager qui entretient la stigmatisation existante et renforce la dépendance. La dimension éthique de ces incidences pratiques et la relation éducative, entre le clinicien et les sujets, les éducateurs et les usagers, en mimèsis dans les dynamiques de changement sont avancés pour éclairer, identifier et prendre du recul.
La précocité, vestige ou destin de l’originaire ?
Authors: Golse Bernard
Published: March 2022

Après quelques rappels sur le concept d’originaire, trois destins possibles de cet originaire (en tant que matériau-socle, en tant que matériau réactivable et en tant que matériau-processus) se trouvent illustrés par différents exemples développementaux. L’auteur aborde ensuite la dialectique qui existe entre le précoce et le profond et qui a été soulignée par Winnicott à propos de l’observation directe des bébés et des possibles conflits entre observateurs et analystes. Pour Winnicott, le profond qui s’analyse renvoie au remaniement fantasmatique du précoce qui s’observe. Le précoce s’inscrit dans le développement, le profond dans l’après-coup. La précocité intellectuelle qui suppose un rapport particulier aux objets épistémiques (rapport non réductible à une simple accélération des processus primaires et secondaires) peut être pensée soit comme un vestige, soit comme un destin d’un précoce non remanié et en lien encore énigmatique avec les processus originaires du fonctionnement psychique.
De l’enfant idéal du siècle des Lumières à l’enfant des limbes de Winnicott
Authors: Ravet-Cialdella Élisabeth
Published: March 2022

L’enfant précoce est à la mode aujourd’hui et le récit biographique de l’infant de Parme nous montre qu’il l’était déjà au xviiie siècle. La découverte de la sexualité infantile dans les Trois essais de Freud a bouleversé la compréhension de la précocité intellectuelle. Un cas clinique nous permet de montrer que la précocité intellectuelle est liée à la précocité sexuelle et à la nostalgie des objets primaires. La séduction ou l’absence de la mère entraînent un emballement des processus psychiques innés. La disparition de l’hallucination primitive pour l’épreuve de réalité est alors mise en échec. Le processus de la pulsion de mort met en branle en s’exprimant par des clivages du moi entraînant une hyperintellectualisation de l’enfant. La pensée de Winnicott a permis de quitter la perspective métapsychologique classique en montrant qu’une déformation du regard sur son enfant entraîne une distorsion du moi chez ce dernier.
Luc ou les ruses de l’intellect
Authors: De Vincenzo Mario
Published: March 2022

L’auteur analyse les différents niveaux de la demande de consultation d’un enfant présentant des signes de précocité pour mettre en évidence la profonde intrication entre l’organisation psychopathologique du jeune patient, son fonctionnement cognitif et les fantasmes parentaux. L’analyse des dynamiques psychiques et de la portée défensive de l’intellect chez l’enfant permettra de comprendre comment l’usage contre-phobique de l’activité mentale peut solliciter des défenses de type maniaques visant à dénier le manque et la dépendance à l’objet. La prise en compte de l’intolérance à la frustration et du besoin de maîtrise à travers l’intellect nous aidera à comprendre comment cette trajectoire subjective permet à l’enfant de créer une forme d’auto-contenance en essayant de dénier la dépendance et les besoins qui relèvent de l’infantile.
Réintrication pulsionnelle masochique par la PPC dans les états de désorganisation psychosomatique
Authors: Thomé Renault Annette
Published: March 2022

L’annonce d’une maladie inéluctablement mortelle constitue pour Yohan un traumatisme actuel, réactivant les traces d’un trauma précoce vécu sans avoir été mentalisé, et provoquant un effondrement dans un état de profonde détresse. Le collapsus psychique et le déferlement d’excitations dans le corps vont être rapidement résolus par la PPC et progressivement les capacités de liaison masochique vont se restaurer dans un plaisir de fonctionnement mental partagé.
La dimension transféro-contre-transférentielle des échanges de regard en PPC et son élaboration
Authors: Caillierez Bertrand
Published: March 2022

Dans cet article, à partir d’un cas clinique suivi en PPC, nous avons mis en perspective l’importance du regard et de la médiation corporelle au sein de la relation transféro-contre-transférentielle. La progression des séances nous a amenés à repérer dans le processus un mouvement où quelque chose s’est noué de manière invasive puis dans un second temps dénoué grâce au rétablissement d’une compréhension bienveillante de la part du psychanalyste. Ces deux événements psychiques et interrelationnels ont permis d’appréhender à travers l’instabilité du fonctionnement mental du patient la présence de bases archaïques insuffisamment construites de son moi. Le travail avec le patient a favorisé un renforcement du contenant psychique. Les traces mnémoniques d’une histoire traumatique de la petite enfance du patient seront traduites et exprimables par la parole sans que son appareil psychique ne risque de voler en éclats. L’analyste peut parvenir comme ici dans le contre-transfert à un hallucinatoire permettant la reprise des traumas et leur appropriation par le patient.
Les avancées de la recherche sur le Moi corporel : leur apport au travail corporel en PPC
Authors: Reignier Sylvie
Published: March 2022

Les apports de G. Haag sur la construction du Moi corporel soutiennent les visées de la PPC : rester dans une préoccupation du corps du patient, tant que ce dernier n’a pu développer une attention et une symbolisation suffisante de ses éprouvés sensoriels et toniques pour leur faire place dans sa vie d’âme. Celle-ci peut pourtant être déjà, dans bien des cas, très développée. Une des ambitions de la PPC est de permettre que la personne secourable des premiers temps de la vie puisse advenir, comme objet interne structurant, sur une scène corporo-psychique plus tolérante à la possibilité de la détresse ; tout aussi important est l’étayage d’un tiers paternel protecteur sur un objet d’arrière-plan solide. C’est par la voie du corps que peuvent être retravaillés, et, espérons-le, transformés les traces des abandons, des attaques d’un surmoi primitif cruel, aussi bien que les retraits du patient dans des zones clivées lui interdisant l’intégration de mouvements objectaux primitifs.
L’armée et le peuple : la doctrine indonésienne de « Défense Populaire Totale » (Pertahanan Keamanan Rakyat Semesta – Hankamrata)
Authors: Striby Francis
Published: March 2022

La doctrine stratégique de l’armée nationale indonésienne ( Tentara Nasional Indonesia – TNI ) est basée sur la notion de « Défense Populaire Totale » ( Pertahanan Keamanan Rakyat Semesta – Hankamrata ). Développée par le Général Abdul Harris Nasution pendant la lutte de libéra­tion nationale de 1945-1949 ( Revolusi ) contre une puissance de feu néerlan­daise supérieure, elle place le peuple au cœur même du dispositif de défense de la nation. Mise en pratique lors d’opérations contre-insurrectionnelles inter­nes et confrontée à de nombreuses interprétations idéologiques au fil de l’histoire de la République d’Indonésie, la Hankamrata reste aujourd’hui, mal­gré un rééquilibrage stratégique de la région indopacifique, plus que perti­nente.
Transitioning Community Health Clinical Experiences to an Online Format During COVID-19
Authors: Perry Julie , Powers S. Cole , Panepinto Robingale
Published: March 2022

Background:

This article describes how nursing students in a community health course transitioned to an online clinical experience when coronavirus disease 2019 limited in-person gatherings.

Method:

A weekly video series was created to provide content to help educate 18 at-risk women using the Plan-Do-Study-Act cycle.

Results:

Objectives for the nursing students were met. Successful implementation occurred, and objectives for the community health class were met; however, engagement was more difficult to achieve.

Conclusion:

Transitioning to online video conferencing allowed the nursing students to still engage with the study participants. Using the PDSA cycle allowed for structured changes to be made.

[
J Nurs Educ
. 2022;61(3):159–161.]
Copulas generated by mixtures of weighted distributions
Authors: Alshehri Mashael A. , Kayid Mohamed
Published: March 2022

In this paper, we characterize several partial dependencies in a general mixture model of weighted distributions with a parametric weight function that encompasses many well-known frailty models. There are well-known frailty models in survival analysis satisfying the proposed mixture model which are used to examine the results. The mixture-based copula functions associated with the mixture model are characterized. Examples are given to draw the copula functions out from respected mixture models.
Potential of polyphenols in curbing quorum sensing and biofilm formation in Gram-negative pathogens
Authors: Lal Arnica F , Singh Shaminder , Franco Francisco C. , Bhatia Sonam
Published: March 2022

Polyphenols are the secondary metabolic products of plants and are considered as active constituents to possess therapeutic effects. To date, a vast number of scientific literature addressed the potential of polyphenols as bio-efficient compounds owing to their structural diversity. Due to the presence of several hydroxyl groups, they are metabolized quickly due to conjugation reaction and thus, readily produce toxic metabolites as a defense material against many pathogens, reflecting their safety strategy. This review focuses on the anti-quorum sensing and biofilm inhibition activity of polyphenols, which display their potential to treat bacterial infections by combating the virulence caused by pathogenic agents. Thus, for mitigating quorum sensing-controlled pathogenesis, the use of polyphenol-based phytochemicals holds immense potential to cure infections. The application of polyphenol as sensitizing agent/ adjuvant therapeutics which act in synergism with antibiotics is highly remarkable.
Ginseng ameliorates pulmonary toxicity induced by silicon dioxide nanoparticles in rats
Authors: El-Sayed Raghda A. , El-Demerdash Fatma M. , El-Magd Mohammed A.
Published: March 2022

Objective:

To investigate the protective and therapeutic role of ginseng against silicon dioxide nanoparticles (SiO2NPs)-induced toxicity in the lungs.

Methods:

Sixty male rats were divided into five groups (n = 12/ group); group 1 was used as a control, group 2 received ginseng, group 3 was treated with SiO2NPs, and group 4 was pretreated with ginseng one week before SiO2NPs, while group 5 was given SiO2NPs one week before supplementation with ginseng. Animals were treated with both ginseng and SiO2NPs orally for five weeks. Real-time PCR was used to measure gene expression. Besides, DNA damage and cell cycle changes were determined by comet assay and flow cytometry, respectively. Histological study was also done to assess the effect of ginseng on SiO2NPs-induced toxicity.

Results:

SiO2NPs increased lipid peroxidation and decreased the activities of antioxidant enzymes. SiO2NPs induced apoptosis in lung tissues as revealed by upregulation of Bax and caspase 3 and downregulation of Bcl-2 as well as the induction of DNA damage. SiO2NPs also caused inflammation as indicated by upregulation of the inflammation-related genes [interleukin 1 beta (IL-1β), tumor necrosis factor-alpha (TNF-α), nuclear factor kappa B (NF-κB), cyclooxygenase 2 (COX2), and transforming growth factor-beta 1 (TGFβ1)] as well as cell cycle arrest in the G0/G1 phase of lung cells. Moreover, histopathological examination proved the biochemical and molecular perturbations that occurred due to SiO2NPs toxicity. However, ginseng alleviated SiO2NPs-induced toxicity in rat lung.

Conclusions:

Ginseng has a potent preventive and therapeutic effect and could be used in the treatment of SiO2NPs-induced pulmonary toxicity.
Potential immunomodulatory role of sesamin in combating immune dysregulation associated with COVID-19
Authors: Majdalawieh Amin F. , Yousef Sarah M. , Abu-Yousef Imad A.
Published: March 2022

The ongoing outbreak of novel coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused an unprecedented global health crisis. Development of a cure for this devastating disease is currently at full speed, with several vaccines against COVID-19 already authorized and administered. Currently, demand for these vaccines far exceeds supply. As such, boosting immunity represents a viable route to halt the rapid spread of SARS-CoV-2 and limit fatalities until vaccines become more readily and widely available. The use of phytochemicals appears to be a promising panacea. Sesamin, a lignan isolated from Sesamum indicum seeds, is known for its potent pharmacological properties, and is therefore hypothesized as a potential candidate in the therapeutic regimen against COVID-19. Herein, we highlight the confirmed therapeutic anti-inflammatory and immune-modulatory potential of sesamin against myriads of respiratory disorders, and tentatively suggest that sesamin may exert similar potent effects against COVID-19. Precisely, we speculate that sesamin may help alleviate COVID-19 via restoring Th1/Th2 balance and preventing inflammation and cytokine storm development. Additionally, we further support the promising role of sesamin against COVID-19 by underscoring the direct evidence, which suggests that sesamin may demonstrate promising inhibitory potential against three important SARS-CoV-2 targets, namely main protease, spike protein, and angiotensin-converting enzyme 2 receptor. Although preliminary, there is ample evidence to propose sesamin as a potential phytotherapeutic and prophylactic candidate against COVID-19. Further in vitro, in vivo, and preclinical studies are required to further substantiate the role of sesamin in the prevention and/or treatment of COVID-19.
Gracilaria fisheri oligosaccharides ameliorate inflammation and colonic epithelial barrier dysfunction in mice with acetic acid-induced colitis
Authors: Siringoringo Brenda , Huipao Nawiya , Tipbunjong Chittipong , Nopparat Jongdee , Wichienchot Santad , Hutapea Albert M. , Khuituan Pissared
Published: March 2022

Objective:

To investigate the effect of Gracilaria fisheri oligosaccharides (GFO) on inflammation and colonic epithelial barrier dysfunction in colitis mice.

Methods:

The animals were treated by oral gavage with distilled water, 1 000 mg/kg inulin, 100, 500, or 1 000 mg/kg GFO for 14 d, or treated with 50 mg/kg mesalamine for 5 d after colitis induction (on day 10). Histopathology, inflammatory cytokines, colonic permeability, and tight junction proteins were investigated by hematoxylin and eosin staining, immunohistochemical staining, Ussing chamber technique, and Western blotting assays, respectively.

Results:

GFO ameliorated histological damage in colitis mice when compared to untreated colitis mice. Treatments with 100, 500, and 1 000 mg/kg GFO reduced TNF-α expression, while IL-1β was significantly reduced in colitis mice treated with 500 and 1 000 mg/kg. Compared to untreated colitis mice, GFO increased transepithelial electrical resistance, reduced fluorescein isothiocyanate-dextran paracellular flux, and modulated tight junction proteins (occludin and claudin 2) in colitis mice.

Conclusions:

GFO has anti-inflammatory activity and could modulate colonic epithelial barrier dysfunction in acetic acid-induced colitis mice. Furthermore, GFO could modulate the expression of tight junction proteins that play important roles in colonic barrier function.
Relaxant Effect of Bioactive Component Compatibility of San-ao Decoction on In vitro Guinea Pig Airway Smooth Muscle
Authors: Song Wen-Jie , Fu Yan-Ling , Ni Sheng-Lou , Fan Jia-Jia , Du Qian , Zheng Hao
Published: March 2022

Background:

Component compatibility is important to the modernization of traditional Chinese medicine. Studies have shown that San-ao decoction (SAD) can treat respiratory diseases by relaxing airway smooth muscle (ASM) and reducing airway hyper-responsiveness. However, whether its bioactive components and compatibility also present with similar relaxant effects remains unknown. This study aims to explore the potential relaxant property, dose-response relationship, and underlying mechanisms of the bioactive component compatibility in SAD.

Methods:

Network pharmacology was primarily used to identify the bioactive components of SAD and uncover its underlying mechanisms. ASM tension force measuring technique was utilized to verify the relaxant and dose-response effects on in vitro guinea pig ASM.

Results:

We postulated pseudoephedrine hydrochloride (PH), amygdalin (AM), and diammonium glycyrrhizate (DG) to be the bioactive components of SAD, which could effectively relax ASM in a dose-dependent manner on both acetylcholine-induced and spontaneous contraction. Both PH and AM could lead to DG dose–response curve shift. The regression equation of these three bioactive components was Y = −2.048 × X1 + 0.411 × X2 + 14.052 × X3 (X1, X2, X3 representing PH, AM, and DG, respectively). The underlying mechanisms of these components might be associated with the regulation of smooth muscle contraction.

Conclusions:

PH, AM, and DG are the bioactive components of SAD, which can relax ASM in a dose–response manner and exert a synergistic effect. Clinically, compatibility of these three bioactive components may serve as a new complementary and alternative treatment for respiratory diseases.
Briefly Revisit Kinematic Control of Redundant Manipulators via Constrained Optimization
Authors: Liao Bolin , Li Jianfeng , Li Shuai , Li Zhan
Published: March 2022

Redundant manipulators are widely utilized in numerous applications among various areas in industry and service. Redundant manipulators take advantage of their inherent or acquired redundancy to achieve certain benefits in kinematic control. Different from non-redundant manipulators, optimization paradigms are more likely to be established and may be more efficient for kinematic control issues in redundant manipulators. In this paper, we revisit the perspective and methodology on constrained optimization paradigms for kinematic control of redundant manipulators.
Evolutionary Computation Based Real-time Robot Arm Path-planning Using Beetle Antennae Search
Authors: Khan Ameer Tamoor , Cao Xinwei , Li Zhan , Li Shuai
Published: March 2022

This paper presents a model-free real-time kinematic tracking controller for a redundant manipulator. Redundant manipulators are common in industrial applications because of the flexibility and dexterity they get from redundant joints. However, at the same time, the modeling of these systems becomes quite challenging, even for simple tasks like trajectory tracking. Some classical approaches are being used to tackle the issue, including a numerical approximation of the Jacobian and pseudo-inverse of the Jacobian matrix. These approaches have their limitations as they require exact parameters for the modeling of the manipulator; they are not immune to position error accumulation with time and put the manipulator way off the target position. Swarm-based meta-heuristic algorithms have given a new direction to the solution of the redundancy resolution problem. However, they are computationally intensive, formulated in discrete-time, and better suited for offline computation rather than real-time. We proposed a novel continuous-time Zeroing Neural Network with Beetle Antennae Search (ZNNBAS). The ZNNBAS algorithm can solve the quadratic optimization problem for redundancy resolution in real-time. To test its performance, we applied it on 7-DOF redundant manipulator with two trajectories to follow: character ``M" and hypotrochoid. The manipulator was able to trace the reference trajectories with minimal tracking errors.
Utilization of Geothermal Water (Şanlıurfa-Karaali) Medium to Enhance DNA Protection and Phycocyanin in Spirulina platensis Production
Authors: Guroy Betul , Bayil Oguzkan Sibel , Guroy Derya
Published: March 2022

Spirulina's industrial use depends on its sustainability and economic production. Geothermal water sources are well known potential water sources for Spirulina' slow-cost production. This research aimed to study the effects on Arthrospira (Spirulina) platensis culture of Sanlıurfa (Karaali) geothermal water. Spirulina was cultured in a 2000 mL Erlenmeyer flask for three weeks. The Schlösser medium (SM) was substituted with 50% and 100% of the volume of the culture medium with the Sanlıurfa geothermal water. The results determined that 3.25 phycocyanin purity ratio (A620/A280), 8% phycocyanin and 38.3% protein in the nutrient medium containing 50% Sanliurfa (Karaali) geothermal water. In the Schlösser Spirulina nutrient medium, defined as the control group, the protein content of 55% and a content of phycocyanin of 16.9% was achieved a phycocyanin purity ratio of 4.43. Although the protein and phycocyanin ratios of Spirulina produced with geothermal water replaced are lower than in Schlösser medium, DNA protective activity of Spirulina produced in the geothermal water of Sanliurfa Karaali showed better protective activity than those produced in the Schlösser medium.
Molecular Evaluation of Human Parvovirus B19 Infection and Associated Risk Factors among Pregnant Women in Bushehr Province, Southern Iran
Authors: Taherkhani Reza , Farshadpour Fatemeh , Norozi Masomeh
Published: March 2022

Given the importance of human parvovirus B19 infection during pregnancy and the potential risks to the fetus, this study was designed to determine the prevalence, genotypic pattern, and risk factors of parvovirus B19 infection among a population-based sample of pregnant women in Bushehr Province, southern Iran. A total of 824 pregnant women were enrolled in this study. Serum samples were screened for the detection of anti-parvovirus B19 IgM and IgG by ELISA. The molecular evaluation was performed by nested polymerase chain reaction, targeting the non-structural protein 1–viral protein 1 unique region of the genome, and sequencing. Of 824 pregnant women, 330 (40.1%) were positive for anti-parvovirus B19 IgG and 50 women (6.1%) had anti-parvovirus B19 IgM. A greater rate of anti-parvovirus B19 IgG seroprevalence was observed in women older than 39 years, in Afghan immigrants, and in those women with more parities. Anti-parvovirus B19 IgM seroprevalence decreased with increasing gestational age and was significantly greater among women in the first trimester of pregnancy and among residents of the city of Borazjan. Moreover, 0.73% of the pregnant women had parvovirus B19 viremia with genotype 1 and subtype 1a. Parvovirus B19 DNA was detected in the samples collected in late autumn and winter, which is a rainy season associated with temperate climes in southern Iran. According to the results of this study, approximately 60% of pregnant women in this region are serologically negative and susceptible to parvovirus B19 infection. Therefore, assessment for maternal parvovirus B19 infection is important and should be considered as part of the fetal–maternal health policy in Iran.
Case Report: Calcified Cerebral Toxoplasmosis Associated with Perilesional Edema in People Living with HIV/AIDS: Case Series of a Presentation Mimicking Neurocysticercosis
Authors: Vidal José E. , Rivero René L. M. , dos Santos Sigrid de Sousa , Guedes Bruno F. , Gomes Hélio R. , Penalva de Oliveira Augusto C. , Garcia Hector H.
Published: March 2022

Perilesional edema, associated or not with neurological manifestations, is a well-characterized finding in cases of calcified neurocysticercosis. There are no previous reports of HIV-related calcified toxoplasmosis that mimics this presentation of neurocysticercosis. We report on five patients, four of them with new-onset neurological manifestations, who showed brain calcifications associated with perilesional edema. All cases had a history of HIV-related toxoplasmosis and current virological and immunological control of HIV infection. Similar to neurocysticercosis, brain calcified toxoplasmosis may cause perilesional edema and symptoms in people living with HIV/AIDS.
Hepato-protective potentials of aqueous, chloroform and methanol leaf extracts of Whitfieldia lateritia on 2, 4-dinitrophenylhydrazine-induced anaemia in rats
Authors: Aja Oti Agha , Egba Simeon Ikechukwu , Uhuo Emmanuel Nnaemeka , Alaebo Prince Ogochukwu , Mba Obinna Joseph , Oriaku Chinwe Edith
Published: March 2022

This study aimed at investigating the hepato-protective potentials of the aqueous, chloroform and methanol leaf extracts of Whitfieldia lateritia on 2, 4-dinitrophenylhydrazine (2,4-DNPH)-induced anaemia in rats. The toxicity study, quantitative phytochemical screening, total and direct bilirubin concentrations, mean protein, albumin and globulin concentrations, as well as mean liver marker enzymes activities (ALT, AST and ALP) were carried out using standard procedures. Thirty-six wistar rats were grouped into six (n =6). Group I: normal control; Group II: negative control; Group III: administered 0.6 ml/kg body weight (b.w) of Astifer (standard Haematinic); Group IV to VI were administered 400 mg/kg b. w. of the aqueous, chloroform and methanol leaf extracts, respectively. Induction of anaemia was achieved in the test groups (II-VI) by administration of 2, 4-dinitrophenylhydrazine (20 mg/kg b.w.) once daily for seven days. Administration of extracts commenced subsequently and lasted for 21 days. Animals were sacrificed on the 22nd day and blood collected for laboratory analysis. ALT, AST and ALP activities of group II anaemic rats showed significant (P < 0.05) reduction compared with normal control rats. Group III rats showed significant (P < 0.05) increase in ALT, AST and ALP activities compared with group II anaemic rats. Group IV rats showed significant (P < 0.05) increase in ALT and AST activity compared with group III rats. The total bilirubin concentration of group II rats was non-significantly (P > 0.05) higher compared with the normal control rats. Groups IV and VI rats showed non-significant (P > 0.05) reduction in total bilirubin concentration compared with group V rats. In conclusion, W. lateritia leaf has beneficial hepato-protective properties in Wistar rats at therapeutic dose that supports its use in the treatment of hepatic diseases
Genetic assessment of Mangifera indica Linn. (Mango) from selected locations in Oyo State, Nigeria
Authors: Olawuyi Joseph Odunayo , Ayodele Abiodun Emmanuel , Ezekiel Precious Chiwendu , Ajayi Isaac Iseoluwa
Published: March 2022

This study characterized five (5) varieties of mango comprising 15 accessions collected from Ogbomosho, Saki, Ibadan and other locations in Oyo State. The field experiment was laid out in a Complete Randomized Design (CRD) with three replicates. Morphological characters were assessed on the stem, leaf and fruit. Also, Molecular studies (DNA amplification and sequencing) were carried out on 15 accessions of mango. The edited sequences were blasted in the National Center of Biotechnology Information (NCBI) data website. The Results showed variability in morphological characters of Mango. Ogbomosho Acc-2 performed best for leaf width (4.53cm) and lamina length (16.25cm) while Isehin Acc-1 had the highest number of leaves per seedling (7.76cm), leaf length (17.06cm), leaf area (38.84cm), petiole length (2.27cm), plant height (24.07cm) respectively. The Number of leaves had positive correlation with Leaf length (r=0.53), Leaf Area (r=0.59), Internodal Length (r= 0.55) and strong positive correlation with plant height (r=0.73) at p≤0.05.  The success rate of amplified DNA products and sequencing was 77.78%. The query coverage of 99% and 100% confirmed positive amplification and sequencing of rbcL gene in the mango varieties.  The sequences blasted in the NCBI data website were identified to be similar to accession KX871231.1. Sequences of rbcL marker showed genetic differences among samples; Grafe and OGBM Acc -1. Genetic distance between varieties from the same location was most often lower with Grafe mango being the most distant variety with genetic distance of 0.114-0.117. There were morphological and molecular variations in mango varieties and accessions. Isehin Acc-1, Saki Acc-1 and OGBM Acc-6 accessions had better growth performance
A Customer Value Approach to Increase Customer Satisfaction and Loyalty at Fast-Casual Dining Restaurant: The Mediating Role of Trust
Authors: Nainggolan Bonifasius M. H. , Soerjanto  , Nurwati Etty , Triana Neni
Published: March 2022

This study investigates the role of trust mediating the relationship between customer satisfaction and loyalty to expand the customer value-satisfaction-loyalty chain to become a customer value-satisfaction-trust-loyalty chain at fast-casual dining restaurants. This research hypothesis test uses the SEM method with LISREL 8.8. The questionnaire was distributed to customers using a convenience sample technique with a final sample size of 250 respondents. Questionnaires distributed to respondents were adapted from the results of previous studies. The results showed that customer value significantly affected customer satisfaction. Satisfaction significantly affects trust. Satisfaction significantly affects customer loyalty both directly and indirectly, and trust substantially increases customer loyalty. The study also showed that trust has a greater influence on customer loyalty than satisfaction. Thus, trust mediates the relationship between customer satisfaction and loyalty. The indirect effect of customer value on loyalty consists of two lines: customer value – satisfaction – loyalty and customer value – satisfaction – trust – loyalty. This research adds an understanding of the customer value-satisfaction-loyalty relationship chain that can be expanded by adding trust as a mediator of satisfaction and loyalty so that a new chain of customer value-satisfaction-trust-loyalty relationships is formed.
The role of the Protestant legacy in shaping Lower Silesian cultural heritage as exemplified by the refuge church in Borek Strzeliński (Großburg)
Authors: Łach Janusz , Krzemińska Alicja , Widawski Krzysztof , Zaręba Anna
Published: March 2022

Protestant refuge churches were built in Silesian Protestant principalities, and in the borderline areas of Saxony, Brandenburg and Poland before the end of Thirty Years’ War and the signing of the Peace of Westphalia. In the most part, the churches were erected by means of adapting Catholic churches to the needs of Protestant believers, e.g. by building emporas (choir galleries), a pulpit and an altar inside the church. The acquisition of churches in Silesia was peaceful, without any violence almost everywhere, and it was not a rare phenomenon that a single church was used by two religions at the same time. At the end of the eighteenth century, there were approximately 110 refugee churches in Silesia. Currently, there are no churches of this type in Lower Silesia, and their extraordinary decoration was preserved in only a few of them. The main aim is to analyse this specific, forgotten sacral Protestent heritage, i.e. refuge churches in Lower Silesia, from the historical, sociological and architectural perspective. The main objective is to focus on the historical importance of the refuge churches in Lower Silesia – restoring identity as exemplified by the church in Großburg (Polish: Borek Strzeliński), analyse the degree to which the Protestant cultural legacy was preserved in the material rural architecture of Großburg and analyse the acceptance of the Evangelical heritage in the mentality of the local community.
The forgotten metamuseological concepts of Wojciech Gluziński
Authors: Lorenc Magdalena
Published: March 2022

Wojciech Gluziński’s metamuseological concepts, developed in the 1960s and 1970s, found their fullest expression in the book U podstaw muzeologii [On the fundamentals of museology] from 1980. Its author was then considered to be one of the pioneers of museological theory in the world. Nevertheless, he is now almost forgotten. This is evidenced by the latest publications of ICOFOM dealing with the history of twentieth-century museology, which exclude Gluziński. The reason for this lack is the language barrier, which makes it difficult to evaluate his achievements in terms of content. The recognition of this state of affairs was the reason for the preparation of this review article using the methods of analysis and criticism of the literature, for which the basis was sources and studies available only in Polish. The basic questions boiled down to how Gluziński understood the museum and what, according to him, the subject of museology was. The answer to the first question was the concept of a “pure” museum, while to the second, the concept of “museum sense”.
OPTIMALISASI PANGKALAN UTAMA TNI ANGKATAN LAUT I BELAWAN GUNA MENJAMIN KEAMANAN LAUT DI SELAT MALAKA
Authors: Monang S.H.S Malau  , Hari Subagyo  , Hendro Yusworo
Published: March 2022

Tujuan dari penelitian ini untuk memberikan sumbangan pemikiran kepada pemimpin, sebagai salah satu upaya pemecahan alternatif dalam mengelola fungsi pangkalan sesuai tipe pangkalan sehingga dapat berfungsi dengan baik sesuai asasi guna mendukung operasi dan latihan unsur di perairan Selat Malaka.Permasalahan yang di temukan yaitu belum optimalnya Sarpras pendukung fungsi 5R. Sumber daya manusia belum memenuhi DSP dengan kualitas yang belum optimal.Organisasi tugas dan prosedur (Orgaspros) belum tertata dengan baik.Selat Malaka merupakan jalur pelayaran terpenting di dunia yang membentuk jalur pelayaran terusan antara Samudra Hindia dan Samudra Pasifik. Sebanyak 50.000 kapal melintasi Selat Malaka setiap tahunnya, mengangkut antara seperlima dan seperempat perdagangan laut dunia.Selat Malaka merupakan salah satu flash point di wilayah Indonesia dengan titik rawan ancaman dan wilayah vital serta daerah perbatasan yang paling mungkin berpotensi menimbulkan konflik, sehingga dukungan pangkalan yang merupakan bagian dari SSAT sangat berperan dalam menjamin keamanan laut di Selat Malaka.Lantamal I Belawan membutuhkan struktur organisasi dan tahapan pembagian tugas yang tertata melalui pola kepemimpinan yang seimbang antara kepentingan organisasi dan pengembangan potensi individu personel
INTERAKSI SOSIAL KKM 46 PADA KEGIATAN KHITAN MASSAL DI DESA BANJARSARI KECAMATAN WARUNG GUNUNG KABUPATEN LEBAK TAHUN 2017
Authors: Fatari  , Asnawi  , Ahmad Munawir  , Surachman  , Gatot Hartoko  , Ardi Hidayat  , Hadi Kurniawanto
Published: March 2022

Khitan atau sunatan sudah sangat familier dan biasa kita dengar. Dibeberapa tempat, acara khitanan anak anak bahkan dijadikan acara hajatan. Namun kegiatan yang dilakukan oleh kelompok 46 merupakan kegiatan pengabdian berupa interaksi social masyarakat. Tujuan dari penulisan ini untuk penyampaian informasi tentang kegiatan Kuliah Kerja Mahasiswa (KKM) Kelompok 46 di desa Banjarsari kecamatan Warung Gunung kabupaten Lebak, dari beberapa program kegiatan, KKM Kelompok 46 melaksanakan program pokok yaitu kegiatan Khitan Massal yang meliputi (1) partisipasi masyarakat dalam kegiatan dan langkah evaluasi terhadap pelaksanaan program dan (2) capaian program kerja dan dampak kegiatan bagi masyarakat khususnya dampak manfaat bagi masyarakat desa Banjarsari. Dalam pelaksanaan Kuliah Kerja Mahasiswa (KKM) STIE Bina Bangsa tahun 2017 oleh kelompok 46 menggunakan  metode Participatory Rural  Appraisal (PRA) dan metode pendekatan social kemasyarakatan. Pelaksanaan kegiatan Khitan Massal ini, diikuti oleh 10 (sepuluh) anak dari keluarga yang kurang mampu perwakilan setiap RT, yang berada di desa Banjarsari, dan berjalan lancar dari awal sampai akhir pelaksanaannya
PELATIHAN PEMASARAN DIGITAL PRODUK DESA NADUNG: KOPI TEH PELAWAN DAN GULA KABUNG
Authors: Eka Rachma Kurniasi  , Rilia Ayuni  , Bima Putra Dewa  , Minarti  , Meliani  , Ridho Pramadhani  , Pitri Yanti  , Dina Zuhriyyah  , Julaiman Alaimusalam  , Eni Artika Sari  , Revaldy
Published: March 2022

Pertumbuhan ekonomi suatu daerah sangat mendukung kualitas usaha yang ada di suatu daerah tersebut. Usaha yang dapat menopang ekonomi daerah tersebut salah satunya adalah usaha produksi kopi teh pelawan dan gula kabung. Produk ini merupakan salah satu produk herbal terletak di Desa Nadung Kecamatan Payung Kabupaten Bangka Selatan. Permasalahan yang dihadapi oleh produsen kopi teh pelawan dan gula kabung adalah kesulitan dalam pemasaran produk yang dihasilkan. Hal ini menyebabkan sedikit yang mengetahui keberadaan produk yang di hasilkan sehingga kecil kemungkinan produk laku terjual. Metode pelatihan dilakukan dengan beberapa tahapan dimulai dari perencanaan, pelaksanaan dan evaluasi.Hasil kegiatan pelatihan pemasaran digital dapat meningkatkan pengetahuan produsen kopi teh pelawan dan gula kabung terkait pemanfaatan media sosial melalui aplikasi Instagram dan facebook untuk membantu produsen dalam memasarkan produk secara digital atau online sehingga dapat dikenal oleh masyarakat luas
PELATIHAN PEMBUATAN HANDSANITIZER ALAMI DENGAN EKSTRAK DAUN SIRIH DAN JERUK NIPIS UNTUK MENCEGAH PENYEBARAN COVID-19 DI DESA CUPAT PARITTIGA
Authors: Ardiansah Feri , Silawati  , Yesi  , Yuhani  , Fatayah Nur Isnani
Published: March 2022

Beberapa cara untuk mencegah penyebaran covid-19 yaitu dengan menerapkan 3 M (mencuci tangan, menjaga jarak, dan menggunakan masker). Semakin bertambahnya kesibukan masyarakat dan menginginkan cara yang praktis dan efisen waktu dalam mencuci tangan, sehingga memunculkan inovasi untuk membuat cairan antiseptik berupa handsanitizer alami. Zat antiseptik yang terdapat didalam handsanitizer memiliki presentase alkohol 60-95%. Terdapat penelitian mengungkapkan bahwa daun sirih dengan kandungan ekstrak lebih dari 15% setara dengan kandungan alkohol dan etanol. Daun sirih mengandung berbagai macam kandungan seperti tanin, polifenol serta steroid. Sedangkan jeruk nipis memiliki kandungan kalsium, fosfor, zat besi, vitamin A, vitamin B1, karbohidrat, kalsium, energi dan vitamin C. Kedua bahan ini mengandung zat anti bakteri. Di desa Cupat tidak semua warga membudidayakan tanaman sirih dan jeruk nipis yang dapat digunakan untuk membuat handsanitizer alami. Handsanitizer alami ini dibuat tanpa campuran  alkohol dan memanfaatkan daun sirih dan jeruk nipis yang ada di desa Cupat. Kegiatan ini adalah rangkuman dari inovasi dan bentuk pelatihan untuk mengajak masyarakat di desa Cupat memahami cara membuat handsanitizer alami ekstrak daun sirih merah dan jeruk nipis.