bluuebunny/crossref_metadata_2025 huggingface dataset:
Analysis of Factors Affecting Trust on the Use of FinTech (P2P Lending) in Indonesia
Authors: Pratama Jimmy
Published: March 2021

Since 2016 the P2P Lending industry has begun to develop in Indonesia. Peer to Peer Lending (P2P Lending) is a new alternative to getting funds in the form of money loans to individuals or investors. Fintech P2P Lending provides convenience through a simple and fast service. Its features can be accessed by anyone, anytime, anywhere. On the other hand, investors or lenders have investment alternatives with attractive returns. So that it quickly spread to all segments of Indonesian society. The purpose of this research is to analyze what factors can influence trust in using of P2P Lending in Indonesia. The difference between this study and previous research is that there is no research that focuses on trust in the use of FinTech, especially P2P Lending in Indonesia. This research is a type of quantitative research that used is primary data obtained by distributing questionnaires directly to Indonesians. The samples taken by Simple Random Sampling Technique and obtained 400 respondents as user fintech. And the statistical analysis used in this study is multiple regression and using SPSS 23 program. Based on the result, this study showed that the variable of structural assurance, easy of use, and brand image were significant on trust in using FinTech, meanwhile the variable of  integrity was not significant on trust in using FinTech.
Tannlæknaótti - kvíði og -fælni meðal nema við Háskóla Íslands
Authors: Ingólfsdóttir Ölrún , Sveinsdóttir Eva
Published: March 2021

Tannlæknaótti, -kvíði og -fælni eru hugtök sem lýsa kvíðatengdri upplifun gagnvart tannlækningum. Slík upplifun getur haft alvarlegar afleiðingar fyrir tannheilsu einstaklinga, sem forðast gjarnan tannlæknaheimsóknir. Slök tannheilsa getur haft víðtæk líkamleg og andleg áhrif því tennur og tannheilsa spila stórt hlutverk þegar kemur að almennum lífsgæðum og vellíðan.
Markmið rannsóknarinnar var að kanna umfang tannlæknaótta, -kvíða og -fælni meðal nema í grunnnámi við Háskóla Íslands.
Aðferðir: Rafræn spurningakönnun var send á alla nemendur skráða í grunnnám við Háskóla Íslands í febrúar 2019. Þekktur alþjóðlegur spurningalisti (MDAS) var notaður til að mæla umfang tannlæknaótta, -kvíða og -fælni meðal nemanna.
Niðurstöður: Af þeim 6995 nemum sem spurningalistinn var sendur til tóku 641 nemandi (9,2%) þátt, en svör frá 637 (9,1%) voru nýtt til úrvinnslu. Konur voru í miklum meirihluta svarenda, 82,7% (n=526), og flestir þátttakendur, 53,3% (n=341), voru á aldursbilinu 20-24 ára. Samkvæmt svörum þátttakenda mældust 19,2% (n=122) með miðlungs tannlæknakvíða, 18,3% (n=115) með mikinn og 26,5% (n=169) með verulegan tannlæknakvíða eða tannlæknafælni. Meirihluti þátttakenda, 88,0% (n=560), hafði sótt sér tannlæknaþjónustu síðastliðin tvö ár.
Ályktun: Niðurstöðurnar benda til að tannlæknakvíði sé raunverulegt vandamál meðal nema í grunnnámi við HÍ. Ætla má að umfang vandans sé sambærilegt meðal annarra þjóðfélagshópa og geti haft áhrif á tannheilsu almennings. Mælt er með því að þeir sem þjást af tannlæknaótta, -kvíða eða -fælni leiti sér faglegrar aðstoðar til að hægt sé að koma í veg fyrir skaðleg áhrif vandans á tannheilsu og lífsgæði.
Tannheilsa í jaðarhópum samfélagsins
Authors: Hede Børge , Palma Patricia , Persson Karin , Lahti Satu
Published: March 2021

Einstaklingar á jaðri samfélagsins mynda hópa sem erfitt getur reynst að nálgast og skilgreina. Samhliða því eru félagsleg vandamál gjarnan til staðar hjá þessum einstaklingum. Í vísindalegu tilliti er áskorun að rannsaka munnheilsutengda þætti hjá jaðarsettum samfélagshópum og kallar sú staðreynd á óhefðbundnar nálganir. Rannsóknir á Norðurlöndunum hafa sýnt fram á nokkrar orsakir fyrir lélegri munnheilsu þessara hópa og hindrarnir hvað varðar meðferð einstaklinga, skipulagningu og stefnumótun. Þörf er á sérsniðnunm áætlunum fyrir tannheilsu jaðarhópa. Háskólar þurfa ennfremur að forgangsraða þessu rannsóknarsviði. Í faraldsfræðilegu og einstaklingsbundnu tilliti er munnheilsa þessara hópa mjög slæm og er þörf á bragabót.
Félagslegar og samfélagslegar afleiðingar tanntaps, verkja vegna kjálkaliðskvilla (tmd) og viðeigandi meðferð
Authors: Øzhayat Esben , Ekberg Ewa
Published: March 2021

Slæm munnheilsa, t.d. tanntap og verkir vegna kjálkaliðskvilla (TMD), getur haft mikil áhrif á lífsgæði og félagsleg tengsl einstaklinga. Þessar einstaklingsbundnu afleiðingar geta að sama skapi haft áhrif á samfélagið, þar sem slæm munnheilsa getur leitt til versnunar á almennu heilsufari og aukið kostnað í heilbrigðiskerfinu, meiri fjarvistum frá vinnu og atvinnuleysi. Ójöfnuður er stór áskorun þegar kemur að tanntapi og bágborin tannheilsa er algengari hjá félagslega viðkvæmum einstaklingum en hjá öðrum. Þessi félagslegi og hagræni ójöfnuður er minna áberandi hvað varðar TMD verki, en þar er algengi mun meira hjá konum. Hjá einstaklingum í viðkvæmri félagslegri stöðu getur fremur einföld og inngrips lítil meðferð með tanngervum verið góður meðferðarkostur og ýmislegt bendir til þess að enduruppbygging tanna geti ýtt undir félagslega endurhæfingu. Hvað varðar TMD verki er mælt með meðferð án inngrips, s.s. fræðslu, góðri sjálfsumhirðu, hugrænni atferlismeðferð, teygjum og bitskinnum.
Habitar Barcelona, habitar el Born en època medieval i moderna. Notes sobre arquitectura domèstica històrica
Authors: González García Reinald
Published: March 2021

La edilícia històrica de Barcelona es mostra en el seu recorregut, com una proposta certament original des de la mateixa fundació romana de la ciutat. Així ho palesen les tècniques constructives, els materials de construcció, els acabats, o fins i tot el mateixos projectes arquitectònic històrics. El testimonis de les cases conservades al conjunt arqueològic del Born, però també en algunes zones de la resta del centre històric de la ciutat explicarien aquesta singularitat: aquest factor local.
Blockchain for social memory institutions: Functional value and possibilities
Authors: Trofimova E. I.
Published: March 2021

De-centralized storage and the closely-coupled related constancy of loaded data, immunity against hacker attacks, transaction history recording and complete transparency make the blockchain technology attractive not only for developing cryptocurrencies and economic transactions. The author reviews the world experience in applying the technology to various activities of social memory institutions and, in particular, individual programs based on the blockchain. The technology enables to provide control and insurance for pieces of art, to ensure copyright, to prevent illegal copying, to store digital copies and ori- ginal works created in the digital environment, to integrate resources using the key functionality of distributed databases. The possibilities and prospects for Russia are evaluated; the need for regulative foundation to define core functionality and legal liability of blockchain processes is emphasized. The possibility for using the technology for building the single knowledge space as the integrative model of digital museum, archival and library resources is analyzed.
“Russian libraries in Germany” – The essays in history
Authors: Ermolaeva M. A.
Published: March 2021

Review of the collection of works prepared by Gottfried Kratz (Gottfried Kratz. Russische Biblioteken in Deutschland. – Berlin : Peter Lang, 2020. – 231 s. (Arbeiten und Bibliographen zum Buch – und Bibliothekswesen. 17).

The book in German comprises the papers by German and Russian researchers on public, academic, military and church libraries in the mid-19th century and up to present. The reviewer focuses on the works matching the profile of the “Scientific and Technical Libraries” journal. The presented works are based on vast archival materials and expand the knowledge of Russian-German library relationships within the mentioned historical period. The researchers of Russian diaspora abroad, book and library historians will make the readership of the book.
Current innovative trends in the CIS national libraries
Authors: Menshchikova S. P.
Published: March 2021

The findings of the study of the development strategies of the CIS na-tional libraries with the reference to the national specifics of the innovative ac-tivities are presented. The goal of the study is to facilitate the cooperation of the libraries within the Commonwealth of Independent States. The analyzed vast em-pirical data is based on expert assessments, consultation papers, publications in periodicals, reports and the libraries’ websites. Sociological and statistical me-thods and comparative analysis were applied. The major problem the national libraries are facing is due to their different degree of digitalization. Based on the empirical data analysis, the major trends were revealed: the key projects are aimed at providing online access to the possibly most complete collections of the CIS national libraries. The current data provided in the paper are predominantly about technological innovations. The CIS national libraries are focused on the programs of e-libraries including national electronic libraries (NELs); projects of global academic Open Access, and structural transformations (designing virtual reading rooms, digital resources sections, book museums, etc.), and educational projects. Innovations have been the strategic priority of the CIS national libraries. Implementing modern information communication technologies facilitates buil-ding common library and information space of the CIS states, while innovative activities enables sharing plans and projects for the CIS national libraries.
Marriages and remarriages: different stages of a dating relationship
Authors: Gomes Isabel Cristina , Levy Lidia
Published: March 2021

Through a close exploration of a clinical case example, the authors intend to explore mutual frustrations inherent in the disruption of a marital relationship and how the illusions the couple deposited in it are reflected in a remarriage. The first marriage lived as a personal failure or defeat affects the establishment of the roles occupied in the second marriage, especially when the second marriage seeks to magically erase its predecessor.
РАЗРАБОТКА И ИССЛЕДОВАНИЕ УНИВЕРСАЛЬНЫХ МОДЕЛЕЙ НАДЕЖНОСТИ АКТИВНОЙ ФАЗИРОВАННОЙ АНТЕННОЙ РЕШЕТКИ МНОГОФУНКЦИОНАЛЬНОЙ РАДИОЛОКАЦИОННОЙ СТАНЦИИ
Authors: Мачалін І. , Костановський В.
Published: March 2021

В роботі проведено короткий аналіз моделей надійності АФАР, запропонованими вченими і інженерами за останні 20 років. Розглянуто модель надійності приймальні АФАР за критерієм допустимого підвищення мінімального рівня бічних пелюсток діаграми спрямованості амплітудно-фазового розподілу антеною решітки. Проаналізовано модель надійності передавальної АФАР за критерієм допустимого зниження максимальної дальності РЛС. Показано, що розглянуті моделі надійності є наближеними (використовують експонентний закон розподілу відмов АФАР) і тому можуть використовуватися тільки для наближеного визначення середнього напрацювання до відмови антеною решітки. Для визначення імовірнісних показників надійності АФАР: ймовірності безвідмовної роботи, інтенсивності відмов, щільності розподілу відмов, гамма-відсоткових ресурсу і ін. Необхідні більш універсальні моделі надійності, що враховують структуру і складність побудови антеною решітки як системи, що складається з величезної кількості основних і резервних приймально передавальних каналів і модулів. У роботі розроблені і досліджені універсальні моделі надійності АФАР багатофункціональної РЛС з дворівневої структурною схемою надійності (дворівнева АФАР). Універсальні моделі надійності враховує два основних фізичних критерію відмови АФАР: допустиме зниження максимального рівня дальності РЛС і припустиме збільшення мінімального рівня бічних пелюсток діаграми спрямованості антеною решітки. Як законів розподілу відмов випромінюючих (передавальних) і прийомних каналів і модулів антеною решітки застосовується експоненціальне розподіл (характеризує раптові відмови), немонотонний диффузионний розподіл (характеризує поступові відмови) і композиція експоненціального і дифузійного немонотонного закону розподілів (характеризує спільне прояв раптових і поступових відмов) . У статті представлені рівняння і формули для визначення показників надійності передавальної, приймальні та приймально-передавальної АФАР: середнього напрацювання до відмови, імовірності безвідмовної роботи та ін.
В роботі розглянуто три ілюстративних прикладу розрахунку показників надійності передавальної, приймальні та приймально-передавальної АФАР при експоненційному розподілі відмов каналів і модулів антеною решітки. Проведено аналіз впливу інтенсивностей відмов випромінюючих каналів і модулів джерел вторинного живлення на середній наробіток до відмови АФАР. Представлені в статті універсальні моделі надійності АФАР рекомендується використовувати при розробці нових багатофункціональних РЛС з АФАР, а також можуть бути корисні студентам і аспірантам університетів і вищих навчальних закладів в навчальному процесі.
РОЗРОБКА МОБІЛЬНОГО ДОДАТКУ «СИСТЕМА ЛОГІЧНОГО РОЗВИТКУ
НА ОСНОВІ КОМП’ЮТЕРНИХ ІГОР “EVOLVE YOUR BRAIN”»
Authors: Наку К. , Шикула О.
Published: March 2021

Індустрія відеоігор развивається швидкими темпами, зоокрема напрямок відеоігор для мобільних платформ. Деякі ігри на мобільному телефоні можуть розвивати особистість. Це логічні ігри. Більшість додатків для розвитку логічного мишлення містять в собі лише одну гру з безліччю рівнів. Майже немає додатків, які б досліджували рівень розвитку інтелекту людини, у користувачів не має можливості відслідковувати свій прогрес, який безперечно існує, адже у будь-якій грі рівень складності підвищується залежно від проходження локацій. Вони також не мають рекомендацій щодо вибору рівня складності у головоломках
Тому актуальною є розробка мобільного застосунку, в якому була б представлена можливість не лише розвивати логічне мислення, але й фіксувати прогрес та визначати рівень логічного мислення людини. Застосунок повинен мати зручний інтерфейс та містити тести і відомі логічні ігри.
Для реалізації програмного продукту використана мова програмування Java та одне з найпопулярніших середовищ для розробки мобільних застосунків – Android Studio. Оскільки додаток має працювати на мобільній платформі Android, то вибране середовище є найкращим рішення для розробки. Для створення можливості грати у гру вдвох була вибрана технологія Bluetooth. Ця технологія є стандартизованою, отже, проблеми несумісності пристроїв від конкуруючих фірм майже не має. Для реалізації програмного продукту використовувалась мова програмування PHP, яка містить ряд готових бібліотек для роботи із популярними базами даних.
Програмний продукт складається з тестів для визначення ступеня логічного розвитку користувача та двох логічних ігор для покращення різних психічних процесів людини – «Судоку» та «Тетріс». Описано функціонування користувацької частини додатку. Застосунок дає змогу користувачеві не лише визначити свій рівень логічного мислення, але й на основі результату тестування дає рекомендації, щодо його покращення за допомогою логічних ігор. Було вибрано дві логічні гри різних типів, щоб користувачі обрали собі те, що потрібно саме їм. Також ігри мають по три рівні складності, що допоможе не лише просто грати, а й удосконалювати свої вміння та навички, покращуючи свій рівень розвитку та інтелекту.
Ключові слова: програмний додаток, логічний розвиток, Android, Android Studio, Java, «Судоку», «Тетріс», головоломка, користувацька частина
BİR KASİDEDEN ONLARCA YENİ YAPITA: TUĞRÂÎ’NİN LÂMİYYETU’L-ʿACEM’İNE YAPILAN TAHMÎS, MUÂRAZA (NAZİRE) VE TAŞTÎRLER
Authors: CENGİZ Mehdi
Published: March 2021

On ikinci asrın önemli şairleri arasında yer alan, Selçuklu Devleti kâtiplerinden Müeyyidüddin et-Tuğrâî’nin Lâmiyyetu’l-ʿAcem adlı kasidesi, zengin muhtevası ve dikkat çeken üslubu ile edebiyat dünyasını etkilemiştir. Bu çerçevede Lâmiyyetu’l-ʿAcem’in, çeşitli şairlerin kaleme aldıkları tahmîs ve muâraza gibi yapıtlarla zemin bir şiir olduğu ifade edilmelidir. Bu çalışmada, Lâmiyyetu’l-Aʿcem’e yazılan tahmîs ve muârazalar incelenerek Tuğrâî’nin, kendisinden sonraki şairlere etkisi ortaya konulacaktır. Ayrıca bu makaleyle klasik Arap edebiyatı şiir üretim metotlarının ve zemin şairin yapıtı ile diğer şairlerin ilişkisinin gösterilmesi de amaçlanmaktadır. Tespit edilen tahmîs ve muâraza gibi yeni metin oluşturmaya yönelik çalışmaların incelenmesiyle İslam düşünce geleneğinde özgün yapıt ortaya koyma metotları hakkında daha kapsamlı değerlendirmeler yapılabilecektir.
Estratégias para melhorar a comunicação entre o Dentista e o paciente adolescente: revisão integrativa da literatura
Authors: Souto Maior Giovanna Burgos , Mayer Trícia Murielly Andrade de Souza , Silva Nayara Kelly Melo , Colares Viviane
Published: March 2021

O objetivo deste estudo foi identificar e descrever possibilidades e estratégias para melhorar a comunicação entre o dentista e o paciente adolescente. Para tanto, realizou-se uma revisão integrativa da literatura mediante busca na base de dados MEDLINE/PubMed usando os descritores: adolescent, child, communication, health communication e dentist. A seleção dos estudos foi realizada por dois pesquisadores, de forma independente. Foram considerados estudos originais que incluíam participantes com idade entre 10 e 19 anos. Primeiro foi realizada a leitura de títulos e resumos, depois a seleção foi mediante leitura dos textos na íntegra. Por fim, seis estudos foram incluídos na revisão, correspondendo a literatura dos últimos oito anos. Um era um estudo transversal e os demais eram Ensaios Randomizados Controlados. Os estudos avaliaram estratégias em relação à comunicação verbal, escrita e virtual, como folhetos impressos, mapas mentais, formulários e recursos digitais. Como desfecho, obtiveram resultados positivos para diminuição da dor, e da ansiedade odontológica, e maior retenção de informações fornecidas pelo cirurgião-dentista. Diante disso, o cirurgião-dentista deve buscar meios adicionais para melhorar a comunicação com o paciente adolescente, e a literatura atual fornece algumas ferramentas com bons resultados, inclusive no que se refere ao atendimento do paciente com ansiedade odontológica. Incluir o resumo.
From olive to olive oil: a general approach
Authors: Silva Bruna Sanches , Schmiele Marcio
Published: March 2021

This study aimed to carry out a systematic literature review about olives, extraction methods, physical and chemical characterization and identity and quality parameters of olive oils, as well as technological alternatives for using by-products. Olive oil is the oil extracted from the ripe fruits of the olive tree (Olea europaea L.). Trees have been cultivated in the Mediterranean Region for several centuries and thousands of cultivars differ by weight, size and chemical characteristics of the fruits. Currently, olive oil is produced worldwide and the olive plant was recently introduced in the city of Diamantina, Minas Gerais. The lipid content is mostly composed of oleic acid and smaller fractions of phenolic compounds, phytosterols and pigments, substances with antioxidant and bioactive activities that promote oxidative stability of the oil and beneficial effects on human health. The main extraction of olive oil consists of crushing, pressing and centrifuging, generating by-products that can be reused for recovery of compounds or generation of new products in the food industry. After extraction, the oil is submitted to several physical and chemical analyzes to define the identity and quality parameters, according to international standards. The main characteristics that define the quality of olive oil are free acidity, peroxide index, specific extinction index, instrumental color and fatty acids profile.
Entendimento e engajamento dos usuários de saúde sobre o Conselho Municipal de Saúde: um relato de experiência
Authors: Holz Luana , Rodrigues Adriani de Souza , Lavall Eliane
Published: March 2021

A Saúde Pública brasileira foi constituída a partir de inúmeros fatores históricos e contou com a participação popular para sua consolidação, processo esse que abriu espaços para manifestação popular e institucionalização do Sistema Único de Saúde (SUS). Esses espaços, após a institucionalização do SUS, são denominados órgãos de controle social, estão dispostos em lei e possuem grande importância para o desenvolvimento de políticas públicas que atendam às necessidades de saúde de pessoas, famílias e comunidade. O presente artigo objetiva compreender o engajamento e entendimento de pessoas residentes em um município do interior do Rio Grande do Sul sobre o Conselho Municipal de Saúde (CMS) local. Trata-se de um estudo qualitativo, descritivo, em que foi realizado um relato de experiências referente a atividade sobre controle social realizada em uma disciplina de Saúde Coletiva, a partir da qual duas estudantes dos cursos de Psicologia e Fisioterapia elaboraram uma enquete para consultar a população sobre seus conhecimentos acerca do órgão. A enquete foi elaborada através de uma plataforma Google e aplicada com usuários do SUS no mês de dezembro de 2020. Os resultados apontam que a população não conhece de fato o CMS e, consequentemente, não exerce efetivamente os seus direitos. Entende-se que a participação social é um processo, relativamente, recente na história do País e que está em processo de construção. No entanto, para que a popularização do controle social ocorra é necessário despender esforços, informar a população e incentivar a sua participação.
Experimental challenge of Atlantic salmon Salmo salar using clones of Paramoeba perurans, P. pemaquidensis and Tetramitus sp.
Authors: Nylund A , Røed M , Blindheim S , Trösse C , Andersen L
Published: March 2021

Salmon gill disease in Norway is in most cases associated with a range of different pathogens, stress and environmental factors. Paramoeba perurans and other amoebae have been isolated during such disease outbreaks. Other amoebae isolated from salmon with gill disease in Norway include P. pemaquidensis, Tetramitus sp. and Vannella sp. Here we tested the pathogenicity of the first 2 species in challenge experiments. We found that even when clonal cultures of P. pemaquidensis established an infection on the gills of salmon, it failed to cause gill disease, while Tetramitus sp. appeared to be unable to establish a lasting infection on the gills of healthy salmon. The result of the challenge with P. pemaquidensis confirms the results of similar studies performed in the USA and in Australia. Tetramitus sp. is probably a common amoeba in the marine environment, and its presence on the gills of farmed salmon may just be accidental. Based on this study, we conclude that P. perurans is the only known amoeba in marine salmon farming associated with amoebic gill disease in Norway.
Predation in littoral habitats is a complex process: Comment on Whitfield (2020)
Authors: Baker R , Sheaves M
Published: March 2021

Shallow littoral waters in estuaries provide important nurseries for a diversity of fish species. The recent review of Whitfield (2020; Mar Ecol Prog Ser 649:219-234) reinforced the long-held paradigm that the value of shallow nurseries is due, in part, to these habitats containing few predators and having low predation pressure. We argue that the provision of refuge does not necessarily mean that a habitat must have few predators and low predation pressure, and present evidence that shallow nurseries contain abundant predator assemblages, may have high predation pressure, and be the habitats where much of the high mortality suffered by juvenile cohorts occurs. Shallow littoral waters are clearly important nurseries, and we highlight the importance of predation in nursery ground functioning.
Optimizing the use of Data Management via Market Intelligence to optimize spending in Indonesian Oil and Gas Sectors
Authors: Sjah Razad Haryo Seto
Published: March 2021

Any purchasing or product and service acquisition comes in hidden costs if we dont have background information on references of reference database. Especially in the oil and gas sector where the cost to acquire those services are higher, market intelligence initiatives plays a pivotal role in ensuring we obtain correct market price data with the help of COBIT5 framework
Mobile Website User Experience (UX) Evaluation on Indonesia's Online Marketplace
Authors: Pratama Khosyi Yoga , Purnama James , Ipung Heru Purnomo
Published: March 2021

Internet economy is growing in Indonesia, and so is the smartphone usage. The popularity of online marketplace is getting bigger by the day yet the market is not utilized as best as it could. A lot of new smartphone user may not be familiar with the concept of mobile application, yet they browse for products to purchase using their mobile web browser. Therefore a mobile website User Experience (UX) evaluation on online marketplace in Indonesia is needed. By using User Experience Questionnaire (UEQ), this research hopes to evaluate which aspect of a marketplace’s mobile website is looked for by its users. An interview is conducted to 30 people to simulate shopping experience on Tokopedia and Bukalapak using a mobile web browser. The result shows that users prefers shopping without having to register, thus making online shopping quick and easy. In addition, user prefers to have all information they need regarding a product in one page rather than having to perform many action to reveal more information.
The Lack of Enforcement of the DRM Policy
Authors: Oliver Stefanus , Winarta Tommy
Published: March 2021

In this digital era, numerous copyrighted items such as music and movies can be enjoyed online. However, our activities in enjoying those entertainments are also limited by the copyright law. Some contents are also protected by Digital Rights Management, which makes sure that the user who purchases the item is the only person who has the right to enjoy the content. All of these rules are obviously made to make sure that everything is in order. Therefore, those illegal activities can be brought to justice. However, the lack of communication might present an ambiguity to the users, and those users might unconsciously do illegal things that are previously forbidden. Other than that, the law itself has its own limitation in the aspect of execution and enforcement, causing pirated versions of a content can be found easily on the internet. This paper is going to review the current condition of the execution of the law regarding the DRM protected contents.
Bildbox! – Virtual Photo Booth that implements Augmented Reality
Authors: Leeson Marchelno , Purnama James , Galinium Maulahikmah
Published: March 2021

The purpose of this research is to develop a self-service photo booth that implements augmented reality which is named as BildBox! where it allows the user of this product to try on different costumes virtually. There will be discussion on the Business Analysis that is conducted in this research to know the potential of the product as well as discussing the features that are implemented in the product. The development of the product’s software will be using Unity game engine and the depth image is taken by using Microsoft’s Kinect v2 depth camera. Aside from the discussions mentioned above, there will be also charts shown from the results of the surveys conducted. In the end, there will be a conclusion drawn from the survey results.
Kivuko cha Watoto: Mafunzo jeuzi kwa watoto na walezi walio athirika na VVU
Authors: Gordon Gill
Published: March 2021

Stepping Stones with Children (available in Swahili) covers a wide range of topics with a gendered and child-rights focused framework and is essential reading for social workers, community workers, health workers and NGO staff working on programmes with people affected by HIV; also researchers and academics teaching and advising in this field.
Transdisciplinary Knowledge Co-production for Sustainable Cities: A guide for sustainable cities
Authors: Hemström Kerstin , Simon David , Palmer Henrietta , Perry Beth , Polk Merritt
Published: March 2021

How can we create appropriate practices for research collaboration in the face of climate change, widening inequalities, decreasing biodiversity and untenable consumption levels? Transdisciplinary co-production focuses on real-world problems through collaborative processes that include a wide variety of knowledge and expertise.
CAN YÜCEL ŞİİRİNDE BİR VAROLUŞ BİÇİMİ OLARAK GÜZELDEN KAÇMAK
Authors: AKPINAR Soner
Published: March 2021

Sanatçının bir insan olarak doğuştan getirdiği mizaç özellikleri yanında özellikle
çocukluk ve ergenlik dönemlerinde çevresiyle kurduğu/kuramadığı ilişkiler, onun yaratma
edimiyle doğrudan ilgilidir. Süperego ile uyum sağlamış bir egonun ürettikleri karşısında, bu
dengeyi kuramamış bir başka egonun ürettikleri arasında yapısal ve tematik bütünlük
bakımından farklar vardır. Can Yücel’in ilk şiirinden son şiirine doğru yapılacak kronolojik bir
okumada göze çarpan ilk şey, şiirlerdeki öznenin gittikçe marjinalleşen bir şekilde güzel ve
güzellik duygusundan uzaklaşmaya başlamasıdır. Bu da bize onun –bahsettiğimiz- süperegoego uyumsuzluğunun içinde olduğunu düşündürmektedir. Şiirlerdeki özne güzel olana karşı
adeta savunma oluşturmuş ve savaş açmış gibidir. Tahammüden girişilen bu tutum ego inşa
ederken kendine özgü bir varoluş biçimi arayan şairin bulduğu sıra dışı yol ile ilgili olmalıdır.
Diğer taraftan şiir türünün estetik ilkeleri düşünüldüğünde bir şairin mesleğine mugayyir bir
şekilde güzellikle işinin olmadığını söylemek de kolay değildir. Şairin hemen her şiirine yansıyan
bu tezatlı durum, onun şiir estetiğinin de en belirgin yönlerinden birini oluşturur. Bu çalışmanın
amacının Can Yücel’in psikolojisini tahlil etmek ya da şiirleri ile psikolojisi arasında bağlantı
kurmak olmadığını öncelikle belirtmek gerekir. Amaç, onun şiirlerinde bu olgunun ne denli
yoğun bir biçimde karşımıza çıktığı ve estetiğinin yapı taşlarından biri olduğunu ortaya
koymaktır.
TÜRKİYE’DE ALEVİLİK- BEKTAŞİLİKLE İLGİLİ HAZIRLANAN SÖZLÜKLERİ ELEŞTİREL OKUMA DENEMESİ
Authors: ŞİMŞEK Emel
Published: March 2021

Türkiye’de Alevîlik ve Bektaşîlikle ilgili son yıllarda pek çok çalışma ortaya konulmuştur.
Alevî-Bektaşî kültürünün farklı yönleri ile ilgili yapılan alan araştırmaları sayesinde pek çok yeni
terim akademik alanlarda tanınmaya başlamıştır. Farklı yörelerdeki Alevî- Bektaşî sahalarından
derlenen yeni terimlerin toplu olarak araştırmacıların hizmetine sunulacağı sözlüklere ihtiyaç
olmasına rağmen bu konuda hazırlanan sözlük çalışmaları ne yazık ki arzu edilen seviyede
değildir. Esat Korkmaz’ın 1993 yılında yayımladığı sözlük 2014 yılına kadar bu alandaki tek
sözlük olarak kalmıştır. 2014’te Alper Çağlayan, küçük bir sözlük yayımlamıştır ve 2019 yılında
Yılmaz Soyyer ve Ahmet Gökbel art arda Alevîlik ve Bektaşîlik terimleri sözlüğü
yayımlamışlardır. Bu çalışmada, bu dört sözlük, kaynak kullanımları, Alevîlik ve Bektaşîliği nasıl
tanımladıkları, bu alanda çalışma yapmanın zorlukları ve bu zorlukların sözlüklere nasıl
yansıdığı bakımından ele alınmıştır. Sözlüklerin madde özellikleri ve kaynak kullanımları tablo
biçiminde karşılaştırılmıştır. Yazarların, bazı terimlere getirdikleri açıklamalar eleştirel bir gözle
karşılaştırılarak Alevîlik konusunda nasıl bir bakış açısı sergiledikleri tespit edilmeye
çalışılmıştır. Sözlüklerde ele alınan terimler değerlendirilerek, yazarların özellikle ağırlık verdiği
alanların olup olmadığı incelenmiştir. Alevîlik-Bektaşilik gibi inançla ilgili bir alanda, Alevîlerin
kendilerini nasıl algıladıkları ve Alevî- Bektâşî terminolojisini açıklama görevini üstlenmiş sözlük
yazarlarının bazı terimleri açıklarken Alevîlerin anlam dünyasına göre mi kendi anlam
dünyalarına göre mi açıklama yaptıkları tespit edilmeye çalışılmıştır. Son olarak da Alevîlik ve
Bektaşîliğe dair hazırlanabilecek yeni bir sözlük önerisinde bulunulmuştur.
KÜLTÜREL DİPLOMASİDE CİNSİYET, TÜRK KADIN DİPLOMATLARIN İŞLEVLERİ
Authors: ÖZDEMİR Yücel
Published: March 2021

Toplumsal ve kültürel değişmeler birçok yeni düşünceleri beraberinde getirmiştir.
Özellikle Batı Aydınlanma Çağı ile ortaya çıkan, ataerkil toplum içindeki kadının yeri üzerine
yapılan toplumsal cinsiyet tartışmaları bunlardan biridir. Toplumsal cinsiyet kuramı, toplumun
ortak belleğinin cinslere yüklediği kültürel kodları çözümleyerek, toplumun cinsiyet kültürünü
sistematik olarak ele almayı amaçlamaktadır. Bununla beraber cinslerin sosyal, siyasal, kültürel
yapı içindeki cinsiyet eşitsizliği durumuna da odaklanmaktadır. Toplumlar, kültür yaşamının her
alanında, toplumsal cinsiyet rollerini, cinsiyet kalıp yargılarını, önyargılarını
yansıtabilmektedirler. Bu açıdan, ulusların dış ilişkilerinde kullandığı kültürel diplomasi alanı,
aynı zamanda onların kültürel kodlarının, cinsiyet kültür algılarının yansıdığı alanlardır. Ulusların
dışişlerinde erkek cinsiyetin hâkim olmasının yanında, kültürel diplomasi de kadınının
görünürlük kazandığı alan olarak karşımıza çıkmaktadır. Diğer taraftan kültürel diplomasi,
ulusların kültürel ifade çeşitliliğini ve zenginliğini göstermesi açısından halkbilimi ile ilişkilidir.
Halkbilimi, bir ulusun kültürel belleğini ve kimliğini oluşturması münasebetiyle kültürel
diplomasiye dikkate değer veri sağlayabilen bir disiplindir. Bunun yanında kadının, kültür
yaşamındaki etkinliklerde başat rol oynadığını söylemek mümkündür. Kadın, kültür tarihinin her
döneminde aktif kültür taşıyıcısı olarak güncelliğini korumuştur. Kültürel diplomasi alanında
kadının konumu üzerine kültürel doku analizi yapıldığında şöyle bir sonuç karşılaşılmaktadır;
Kadın, halkbilgisini aktaran, yaşatan, ötekiyle etkileşimde bulunduran bir aktördür. Bu açıdan
kültürel diplomasi çalışmalarında kadın imgesini ve işlevlerini toplumsal cinsiyet açısından ele
almak, dikkate değerdir. Makalede, Avrupa’da cinsiyet kültürü ve diplomasi odağında literatür
taraması sunulacaktır. Türk kültür tarihinde kadının iç ve dışişlerdeki rolü, sözlü ve yazılı
kaynaklar ile tartışılacaktır. T.C. Dışişleri Bakanlığı’nda görev yapmış Türk kadın diplomatları ve
diplomat eşi olarak kadının, kültürel diplomasideki yeri ve işlevleri cinsiyet kültürü bağlamında
incelenecektir
Correlation Research on the Practice of School Administrative Ethics and Teachers’ Job Morale and Job Involvement
Authors: ZHAO Ruobing , LI Zhen , HUANG Yige
Published: March 2021

Being in such a highly competitive knowledge economic era with changing social value and fast information spread, the relationship between school teachers and staff is different from it in the past and the dilemmas and difficulties encountered by schools are increasing. School administrators have to face problems and accept challenges on policy promotion and work execution and even have to immediately make decisions on certain issues. School administrators’ decisions mostly involve in people that the considerations are broad, e.g. conforming to education objectives, taking care of different learners’ needs, and satisfying various stakeholders. Aiming at university teachers in Shandong Province as the empirical objects, total 360 copies of questionnaire are distributed for this study. 254 valid copies are retrieved, with the retrieval rate 71%. According to the research results, suggestions are proposed, expecting to help domestic universities and colleges enhance the practice of administrative ethics, stimulate and promote the administrative effectiveness of schools, and enhance the overall effectiveness.
The Limitless Future of RNA Therapeutics
Authors: Damase Tulsi Ram , Sukhovershin Roman , Boada Christian , Taraballi Francesca , Pettigrew Roderic I. , Cooke John P.
Published: March 2021

Recent advances in the generation, purification and cellular delivery of RNA have enabled development of RNA-based therapeutics for a broad array of applications. RNA therapeutics comprise a rapidly expanding category of drugs that will change the standard of care for many diseases and actualize personalized medicine. These drugs are cost effective, relatively simple to manufacture, and can target previously undruggable pathways. It is a disruptive therapeutic technology, as small biotech startups, as well as academic groups, can rapidly develop new and personalized RNA constructs. In this review we discuss general concepts of different classes of RNA-based therapeutics, including antisense oligonucleotides, aptamers, small interfering RNAs, microRNAs, and messenger RNA. Furthermore, we provide an overview of the RNA-based therapies that are currently being evaluated in clinical trials or have already received regulatory approval. The challenges and advantages associated with use of RNA-based drugs are also discussed along with various approaches for RNA delivery. In addition, we introduce a new concept of hospital-based RNA therapeutics and share our experience with establishing such a platform at Houston Methodist Hospital.
Preconditioning Human Adipose-Derived Stromal Cells on Decellularized Adipose Tissue Scaffolds Within a Perfusion Bioreactor Modulates Cell Phenotype and Promotes a Pro-regenerative Host Response
Authors: Han Tim Tian Y. , Walker John T. , Grant Aaron , Dekaban Gregory A. , Flynn Lauren E.
Published: March 2021

Cell-based therapies involving the delivery of adipose-derived stromal cells (ASCs) on decellularized adipose tissue (DAT) scaffolds are a promising approach for soft tissue augmentation and reconstruction. Our lab has recently shown that culturing human ASCs on DAT scaffolds within a perfusion bioreactor prior to implantation can enhance their capacity to stimulatein vivoadipose tissue regeneration. Building from this previous work, the current study investigated the effects of bioreactor preconditioning on the ASC phenotype and secretory profilein vitro, as well as host cell recruitment following implantation in an athymic nude mouse model. Immunohistochemical analyses indicated that culturing within the bioreactor increased the percentage of ASCs co-expressing inducible nitric oxide synthase (iNOS) and arginase-1 (Arg-1), as well as tumor necrosis factor-alpha (TNF-α) and interleukin-10 (IL-10), within the peripheral regions of the DAT relative to statically cultured controls. In addition, bioreactor culture altered the expression levels of a range of immunomodulatory factors in the ASC-seeded DAT.In vivotesting revealed that culturing the ASCs on the DAT within the perfusion bioreactor prior to implantation enhanced the infiltration of host CD31+endothelial cells and CD26+cells into the DAT implants, but did not alter CD45+F4/80+CD68+macrophage recruitment. However, a higher fraction of the CD45+cell population expressed the pro-regenerative macrophage marker CD163 in the bioreactor group, which may have contributed to enhanced remodeling of the scaffolds into host-derived adipose tissue. Overall, the findings support that bioreactor preconditioning can augment the capacity of human ASCs to stimulate regeneration through paracrine-mediated mechanisms.
A Novel Fast-Setting Strontium-Containing Hydroxyapatite Bone Cement With a Simple Binary Powder System
Authors: Sun Lijuan , Li Tongyang , Yu Sen , Mao Mengmeng , Guo Dagang
Published: March 2021

In recent years, strontium-substituted calcium phosphate bone cement (Sr-CPC) has attracted more and more attentions in the field of bone tissue repair due to its comprehensive advantages of both traditional CPC and Sr ions. In this study, a crucial Sr-containing α-Ca3–xSrx(PO4)2 salt has been synthesized using a simplified one-step method at lower synthesis temperature. A novel Sr-CPC has been developed based on the simple binary Sr-containing α-Ca3–xSrx(PO4)2/Ca4(PO4)2O cement powder. The physicochemical properties and hydration mechanism of this Sr-CPC at various Sr contents were intensively investigated. The setting product of this Sr-CPC after a set for 72 h is a single-phase Sr-containing hydroxyapatite, and its compressive strength slightly decreased and its setting time extended with the increase of Sr content. The hydration process included the initial formation of the medium product CaHPO4⋅2H2O (30 min∼1 h), the following complete hydration of Ca4(PO4)2O and the initially formed CaHPO4⋅2H2O (2∼6 h), and the final self-setting of α-Ca3–xSrx(PO4)2 (6 h∼). The compressive strength of Sr-CPC, which was closely related to the transformation rate of Sr-containing hydroxyapatite, tended to increase with the extension of hydration time. In addition, Sr-CPC possessed favorable cytocompatibility and the effect of Sr ions on cytocompatibility of Sr-CPC was not obvious at low Sr contents. The present study suggests α-Ca3–xSrx(PO4)2 is a kind of vital Sr-containing salt source which is useful to develop some novel Sr-containing biomaterials. In addition, the new Sr-containing cement system based on this simple binary α-Ca3–xSrx(PO4)2/Ca4(PO4)2O cement powder displayed an attractive clinical application potential in orthopedics.
Human Wharton’s Jelly Stem Cell Secretions Inhibit Human Leukemic Cell Line K562 in vitro by Inducing Cell Cycle Arrest and Apoptosis
Authors: Huwaikem Muneerah A. H. , Kalamegam Gauthaman , Alrefaei Ghadeer , Ahmed Farid , Kadam Roaa , Qadah Talal , Sait Khalid H. W. , Pushparaj Peter N.
Published: March 2021

Emerging resistance to the tyrosine kinase inhibitors that target the BCR-ABL1 oncoprotein has prompted research for novel therapeutics against chronic myeloid leukemia (CML). Herein, we evaluated the tumor inhibitory properties of the human Wharton’s jelly stem cells (hWJSCs) co-culture (hWJSC-CC) and their extracts, namely, the hWJSC-conditioned medium (hWJSC-CM; 100%) and hWJSC-lysate (hWJSC-L; 15 μg/ml), on a CML cell line K562 in vitro. The hWJSCs expressed mesenchymal stem cell (MSC)-related cluster of differentiation (CD) markers and demonstrated mesodermal tissue differentiation potential. The cell metabolic activity showed a mean maximal decrease in the K562 cells by 49.12, 41.98, and 68.80% following treatment with the hWJSC-CC, hWJSC-CM, and hWJSC-L, respectively, at 72 h. The sub-G1 population in the cell cycle was decreased by 3.2, 4.5, and 3.8% following treatment with the hWJSC-CC, hWJSC-CM, and hWJSC-L, whereas the G2/M cell population was increased by 13.7 and 12.5% with the hWJSC-CM and hWJSC-L, respectively, at 48 h. Annexin V–allophycocyanin (APC) assay showed an increase in the apoptotic cells by 4.0, 3.9, and 4.5% at 48 h. The expression of pro-apoptotic BAX and CASP3 genes were increased, whereas BIRC5 (Survivin) was decreased compared with the control. The pro-inflammation-related genes, namely, IFN-γ, TNF-α, IL-1β, IL-6, IL-8, and IL-12A, were decreased, whereas the anti-inflammatory genes, namely, IL-4 and IL-10, were increased following treatment with the hWJSC-CC, hWJSC-CM, and hWJSC-L at 48 h. Multiplex bead-based cytokine assay also demonstrated decreases in the pro-inflammatory cytokines (IFN-γ, TNF-α, IL-1β, IL-6, and IL-12) and an increase in the anti-inflammatory cytokine (IL-10) compared with the control. The pro-inflammatory cytokine IL-8 showed an increase with the hWJSC-CC and decreases with both the hWJSC-CM and the hWJSC-L. The hWJSCs and their extracts inhibited the K562 cells by causing cell cycle arrest and inducing apoptosis via the soluble cellular factors. However, an in vivo evaluation is necessary to unravel the true potential of the hWJSCs and their extracts before its use in CML inhibition.
Graphene Oxide and Reduced Graphene Oxide Exhibit Cardiotoxicity Through the Regulation of Lipid Peroxidation, Oxidative Stress, and Mitochondrial Dysfunction
Authors: Zhang Jian , Cao Hong-Yan , Wang Ji-Qun , Wu Guo-Dong , Wang Lin
Published: March 2021

Objective

Graphene has been widely used for various biological and biomedical applications due to its unique physiochemical properties. This study aimed to evaluate the cardiotoxicity of graphene oxide (GO) and reduced GO (rGO)in vitroandin vivo, as well as to investigate the underlying toxicity mechanisms.

Methods

GO was reduced by gamma irradiation to prepare rGO and then characterized by UV/visible light absorption spectroscopy. Rat myocardial cells (H9C2) were exposed to GO or rGO with different absorbed radiation doses. Thein vitrocytotoxicity was evaluated by MTT assay, cell apoptosis assay, and lactate dehydrogenase (LDH) activity assay. The effects of GO and rGO on oxidative damage and mitochondrial membrane potential were also explored in H9C2 cells. Forin vivoexperiments, mice were injected with GO or rGO. The histopathological changes of heart tissues, as well as myocardial enzyme activity and lipid peroxidation indicators in heart tissues were further investigated.

Results

rGO was developed from GO following different doses of gamma irradiation.In vitroexperiments in H9C2 cells showed that compared with control cells, both GO and rGO treatment inhibited cell viability, promoted cell apoptosis, and elevated the LDH release. With the increasing radiation absorbed dose, the cytotoxicity of rGO gradually increased. Notably, GO or rGO treatment increased the content of ROS and reduced the mitochondrial membrane potential in H9C2 cells.In vivoexperiments also revealed that GO or rGO treatment damaged the myocardial tissues and changed the activities of several myocardial enzymes and the lipid peroxidation indicators in the myocardial tissues.

Conclusion

GO exhibited a lower cardiotoxicity than rGO due to the structure difference, and the cardiotoxicity of GO and rGO might be mediated by lipid peroxidation, oxidative stress, and mitochondrial dysfunction.
Modeling Neuroregeneration and Neurorepair in an Aging Context: The Power of a Teleost Model
Authors: Van houcke Jolien , Mariën Valerie , Zandecki Caroline , Seuntjens Eve , Ayana Rajagopal , Arckens Lutgarde
Published: March 2021

Aging increases the risk for neurodegenerative disease and brain trauma, both leading to irreversible and multifaceted deficits that impose a clear societal and economic burden onto the growing world population. Despite tremendous research efforts, there are still no treatments available that can fully restore brain function, which would imply neuroregeneration. In the adult mammalian brain, neuroregeneration is naturally limited, even more so in an aging context. In view of the significant influence of aging on (late-onset) neurological disease, it is a critical factor in future research. This review discusses the use of a non-standard gerontology model, the teleost brain, for studying the impact of aging on neurorepair. Teleost fish share a vertebrate physiology with mammals, including mammalian-like aging, but in contrast to mammals have a high capacity for regeneration. Moreover, access to large mutagenesis screens empowers these teleost species to fill the gap between established invertebrate and rodent models. As such, we here highlight opportunities to decode the factor age in relation to neurorepair, and we propose the use of teleost fish, and in particular killifish, to fuel new research in the neuro-gerontology field.
A Balanced Act: The Effects of GH–GHR–IGF1 Axis on Mitochondrial Function
Authors: Hu Bowen , Li Hongmei , Zhang Xiquan
Published: March 2021

Mitochondrial function is multifaceted in response to cellular energy homeostasis and metabolism, with the generation of adenosine triphosphate (ATP) through the oxidative phosphorylation (OXPHOS) being one of their main functions. Selective elimination of mitochondria by mitophagy, in conjunction with mitochondrial biogenesis, regulates mitochondrial function that is required to meet metabolic demand or stress response. Growth hormone (GH) binds to the GH receptor (GHR) and induces the JAK2/STAT5 pathway to activate the synthesis of insulin-like growth factor 1 (IGF1). The GH–GHR–IGF1 axis has been recognized to play significant roles in somatic growth, including cell proliferation, differentiation, division, and survival. In this review, we describe recent discoveries providing evidence for the contribution of the GH–GHR–IGF1 axis on mitochondrial biogenesis, mitophagy (or autophagy), and mitochondrial function under multiple physiological conditions. This may further improve our understanding of the effects of the GH–GHR–IGF1 axis on mitochondrial function, which may be controlled by the delicate balance between mitochondrial biogenesis and mitophagy. Specifically, we also highlight the challenges that remain in this field.