bluuebunny/crossref_metadata_2025 huggingface dataset:
Widening the divide: the impact of school closures on primary science learning
Authors: Canovan Cherry , Fallon Naomi
Published: May 2021

Prolonged Covid-19-related school closures in the UK raised concerns that science teaching and learning at primary level would be negatively impacted. This paper reports the findings of phase 1 of a study that the authors are conducting with teachers and parents to explore this issue. We found that a significant proportion of teachers were providing less science during lockdown than in the normal school week. Teachers, particularly those working in more deprived areas, reported that translating the science curriculum for home learning had been difficult, with concerns around resources, internet access and parental ability to help. Some areas of the curriculum posed particular difficulties, leading to a narrowing of topics being taught. Both teachers and parents felt that schools prioritised English and maths above science. Meanwhile some parents reported that their children had engaged in sophisticated extracurricular activities, bolstered by resources available at home and knowledgeable adult help, but others said that their children had done no science at all. Parents who had studied science at post-compulsory level were much more comfortable in helping their children with science home learning. These factors combine to create conditions which may exacerbate existing inequalities as to who can access science education and careers.
Conceptual and normative approaches to AI governance for a global digital ecosystem supportive of the UN Sustainable Development Goals (SDGs)
Authors: Gill Amandeep S. , Germann Stefan
Published: May 2021

AI governance is like one of those mythical creatures that everyone speaks of but which no one has seen. Sometimes, it is reduced to a list of shared principles such as transparency, non-discrimination, and sustainability; at other times, it is conflated with specific mechanisms for certification of algorithmic solutions or ways to protect the privacy of personal data. We suggest a conceptual and normative approach to AI governance in the context of a global digital public goods ecosystem to enable progress on the UN Sustainable Development Goals (SDGs). Conceptually, we propose rooting this approach in the human capability concept—what people are able to do and to be, and in a layered governance framework connecting the local to the global. Normatively, we suggest the following six irreducibles: a. human rights first; b. multi-stakeholder smart regulation; c. privacy and protection of personal data; d. a holistic approach to data use captured by the 3Ms—misuse of data, missed use of data and missing data; e. global collaboration (‘digital cooperation’); f. basing governance more in practice, in particular, thinking separately and together about data and algorithms. Throughout the article, we use examples from the health domain particularly in the current context of the Covid-19 pandemic. We conclude by arguing that taking a distributed but coordinated global digital commons approach to the governance of AI is the best guarantee of citizen-centered and societally beneficial use of digital technologies for the SDGs.
Modeling human activity dynamics: an object-class oriented space–time composite model based on social media and urban infrastructure data
Authors: Zhang Zhe , Yin Dandong , Virrantaus Kirsi , Ye Xinyue , Wang Shaowen
Published: May 2021

Modeling human activity dynamics is important for many application domains. However, there are problems inherent in modeling population information, since the number of people inside a given area can change dynamically over time. Here, a cyberGIS-enabled spatiotemporal population model is developed by combining Twitter data with urban infrastructure registry data to estimate human activity dynamics. This model is an object-class oriented space–time composite model, in which real-world phenomena are modeled as spatiotemporal objects, and people can move from one object to another over time. In this research, all spatiotemporal objects are aggregated into 14 spatiotemporal object classes, and all objects in a given space at different times can be projected down to a spatial plane to generate a common spatiotemporal map. A temporal weight matrix is derived from Twitter activity curves for each spatiotemporal object class and represents population dynamics for each object class at different hours of a day. Finally, model performance is evaluated by using a comparison to registered census data. This spatiotemporal human activity dynamics model was developed in a cyberGIS computing environment, which enables computational and data intensive problem solving. The results of this research can be used to support spatial decision-making in various application areas such as disaster management where population dynamics plays an important role.
A carbon neutral chemical industry powered by the sun
Authors: González-Garay Andrés , Mac Dowell Niall , Shah Nilay
Published: May 2021

The decarbonisation of the chemical industry requires a transformation of the sources of energy, raw materials, and structure of the sector. The production of chemicals by converting fossil fuels is a pillar of the modern economy, consuming 10% of global energy demand and releasing 7% of global CO2emissions. Being the most abundant source of energy available to humankind, solar energy can provide solutions across the different needs identified to deploy a low-carbon and sustainable industry. However, its transformation into functional energy and chemical feedstocks presents multiple challenges at the technical, economic, environmental, and social levels. While solar energy is being largely deployed, its incorporation within the chemical sector requires a guarantee of supply at feasible costs. Analysing alternative feedstocks, even mature processes struggle to reach competitive prices, a situation that worsens as technologies at early development stage are considered. Despite these, and other challenges, the use of solar energy is a general trend that is widely accepted within the chemical and other industries, with increasing research efforts aiming to present solutions to guarantee its sustainable implementation. The penetration of these technologies into the existing structure of the sector calls for a process systems engineering thinking, which combined with life cycle assessment, can shed light into the sustainable deployment of solar-based processes. On this basis, we present the status of solar technologies and their potential contribution to achieve a sustainable industry. This perspective thus presents an analysis of solar technologies that can support the transition of the sector in the short, middle, and long term, and the challenges inherent to their implementation. While the transition of the chemical industry from fossil fuels to solar technologies seems promising and shows significant abatement of CO2emissions, it is expected to occur at the expense of higher production costs and unintended environmental burden shifting. Therefore, the application of sustainable process systems thinking at a multi-scale level will be key to identify energy-efficient and highly-integrated systems deployed within local and regional contexts. These tools will ultimately assist the decision-making process to guide a global environmental policy framework that promotes sustainable development and ensures competitiveness of the sector across multiple regions.
The Tampon Test as a Primary Outcome Measure in Provoked Vestibulodynia: A Mixed Methods Study
Authors: Kaarbø Mette Bøymo , Danielsen Kristine Grimen , Haugstad Gro Killi , Helgesen Anne Lise Ording , Wojniusz Slawomir
Published: May 2021

Background

Provoked vestibulodynia (PVD) is characterized by severe pain, often induced by penetrative sex. This may lead to women abstaining from sexual intercourse, hence the recording of pain intensity levels in PVD research is often challenging. The standardized tampon test was designed as an alternative outcome measure to sexual intercourse pain and has frequently been used in clinical studies.

Aim

The aim of this mixed methods study is to evaluate the tampon test as a primary outcome measure for an upcoming randomized clinical trial for women with PVD.

Methods

An explanatory sequential design was applied, integrating quantitative and qualitative methods. In phase one, pain intensity levels were evaluated with the tampon test amongst 10 women, aged 18-33, with PVD. The test was repeated on day 1, 7 and 14. Pain intensity was rated on the Numerical Rating Scale (NRS), (0-10), 10 being worst possible pain. In phase two, the participants’ experiences with the test were explored with semi-structured interviews using a descriptive and inductive qualitative design. All participants were recruited from the Vulva Clinic, Oslo University Hospital, Norway.

Outcomes

The tampon test data and interviews were brought together to see how the interviews could refine and help to explain the quantitative findings.

RESULTS

The tampon test data demonstrated large intra- and inter-individual variability. Median tampon pain intensity was 4.5 (min=1.7; max=10; Q1=2.5; Q3=6). Many experienced the test as an inadequate representation of pain during intercourse as it was less painful, different in nature and conducted in an entirely different context. Four participants had a mean score of four or lower on the NRS, whilst concurrently reporting high levels of pain during sexual intercourse.

Clinical Implications

The findings indicate that the tampon test may underestimate severity of pain among some women with PVD. Participants with low pain scores would be excluded from studies where the tampon test is part of the trial eligibility criteria, even though severe pain was experienced during sexual intercourse. Large intra-individual variability in pain scores also reduces the test’s ability to register clinical meaningful changes and hence necessitates repeated measurements per assessment time point.

CONCLUSION

Although the tampon test has many advantages, this study indicates several potential problems with the application of the test as a primary outcome measure in PVD. In our opinion the test is most useful as a secondary outcome, preferably undertaken repeatedly in order to increase precision of the pain estimation.
A National Survey of Wilderness Medicine Curricula in United States Emergency Medicine Residencies
Authors: Goldflam Katja , Coughlin Ryan F. , Cotton Widdicombe A. , Della-Giustina David
Published: May 2021

Introduction

Wilderness medicine (WM) is a growing subspecialty of emergency medicine. In 2018, we surveyed all 240 emergency medicine residencies in the United States to assess the scope of WM education in emergency medicine training programs in light of the nearly 30% increase in the number of residencies since 2015.

Methods

A survey was e-mailed to the Council of Residency Directors in Emergency Medicine listserv and individual program directors of each of the 240 residencies. The survey included questions on educational content, format, number of hours taught, availability of conference credit, offering of an elective or fellowship, and several predefined WM curricula. We evaluated differences between 3-y and 4-y residencies using the χ2 test, where P<0.05 was considered significant.

Results

We had a response rate of 57% for completed surveys. Analysis showed 63% of respondent programs teach WM material. The majority (86%) partially or completely developed their curriculum, with 33% offering at least 1 of the predefined curricula. Thirteen percent taught with lecture only, 2% taught by hands-on only, and 85% used a combination of the 2. WM electives were significantly more likely to be offered by 4-y than 3-y residencies ( P=0.009).

Conclusions

Almost two-thirds of respondent residency programs teach WM material. Of these, only one-third teach any of the predefined curricula. Four-year residencies are more likely to offer WM electives but are otherwise comparable to 3-y programs.
Infrared signal of the lobed mixer with external air mixing
Authors: Choi S.M. , Jang H.S. , Park H.H.
Published: May 2021

In order to know the characteristics of reducing the exhaust gas infrared signal of the lobed mixer according to the external air mixing ratio, an infrared signal and temperature distribution measurement using a micro-turbojet engine is performed. A certain amount of compressed air is supplied through an external duct mounted on the micro-turbojet engine exhaust to simulate bypass flow, which is mixed with high-temperature core air and ejected to the atmosphere. The exhaust nozzle used in the experiment is a lobed mixer with a lobe of sinusoidal shape and is designed to have a penetration of 0.2. Exhaust gas temperature and infrared signal are measured according to distance from nozzle outlet under conditions of bypass ratio of 0.5, 1.0 and 1.4. Infrared reduction rates are compared to data without compressed air supply. As a result of the experiment, as the bypass ratio increased, the infrared signal of the exhaust gas and the temperature decrease with bypass ratio increase, and in the case of a bypass ratio of 1.4, the effect of reducing the temperature is observed even at a long distance. In addition, we compared the results of previous studies of a simple cone shape without mixer with infrared reduction effect. The results show that the lobed mixer has a greater effect on reducing the temperature of the exhaust gas and reducing the infrared signal than the cone nozzle. The structure of the mixed jet flow is also studied through Schlieren visualisation and 3D temperature distribution.
TUKEY ORDER AMONG IDEALS
Authors: HE JIALIANG , HRUŠÁK MICHAEL , ROJAS-REBOLLEDO DIEGO , SOLECKI SŁAWOMIR
Published: May 2021

We investigate the Tukey order in the class of
$F_{\sigma }$
ideals of subsets of
$\omega $
. We show that no nontrivial
$F_{\sigma }$
ideal is Tukey below a
$G_{\delta }$
ideal of compact sets. We introduce the notions of flat ideals and gradually flat ideals. We prove a dichotomy theorem for flat ideals isolating gradual flatness as the side of the dichotomy that is structurally good. We give diverse characterizations of gradual flatness among flat ideals using Tukey reductions and games. For example, we show that gradually flat ideals are precisely those flat ideals that are Tukey below the ideal of density zero sets.
THE RELATIVIZED LASCAR GROUPS, TYPE-AMALGAMATION, AND ALGEBRAICITY
Authors: DOBROWOLSKI JAN , KIM BYUNGHAN , KOLESNIKOV ALEXEI , LEE JUNGUK
Published: May 2021

In this paper we study the relativized Lascar Galois group of a strong type. The group is a quasi-compact connected topological group, and if in addition the underlying theory T is G-compact, then the group is compact. We apply compact group theory to obtain model theoretic results in this note. For example, we use the divisibility of the Lascar group of a strong type to show that, in a simple theory, such types have a certain model theoretic property that we call divisible amalgamation. The main result of this paper is that if c is a finite tuple algebraic over a tuple a, the Lascar group of
$\operatorname {stp}(ac)$
is abelian, and the underlying theory is G-compact, then the Lascar groups of
$\operatorname {stp}(ac)$
and of
$\operatorname {stp}(a)$
are isomorphic. To show this, we prove a purely compact group-theoretic result that any compact connected abelian group is isomorphic to its quotient by every finite subgroup. Several (counter)examples arising in connection with the theoretical development of this note are presented as well. For example, we show that, in the main result above, neither the assumption that the Lascar group of
$\operatorname {stp}(ac)$
is abelian, nor the assumption of c being finite can be removed.
Factors affecting the seasonal variability of planktonic shrimps (Dendrobranchiata) along an estuary–ocean gradient on the Amazon continental shelf
Authors: da Silva Leiliane Souza , Cavalcante-Braga Danielle Viveiros , Lourenço Caio Brito , Schwamborn Ralf , Martinelli-Lemos Jussara Moretto
Published: May 2021

Dendrobranchiata shrimp taxonomic composition and spatial and temporal distribution on the Amazon continental shelf (ACS) were investigated along a transect between the sources of the Amazon and Pará Rivers, encompassing an extension of ~250 km towards the continental slope. Plankton was collected with oblique trawls (200 μm mesh size), and nine taxa were found; 59.4% were larvae (mysis or decapodid stages) and 40.6% were juveniles or adults. Acetes was negatively related to chlorophyll-a and temperature, and Luciferidae were positively correlated with months. This study provides novel information on the density distribution of dendrobranchiate shrimps, thus helping to pave the way to characterize a large-scale, hugely relevant area that is poorly studied. As in other tropical coastal areas, there is here an increase in number of taxa with increased distance from the coast. Luciferidae, Solenoceridae and Penaeidae were the most frequent families whereas Sicyoniidae and Sergestidae had the lowest frequency of occurrence nearer the slope. Despite the low larval density of penaeid shrimps, their presence in all months and at all sampling sites along the ACS proves the importance of this area for shrimps with socioeconomic relevance, as well as its importance as a nursery and growth habitat for dendrobranchiate shrimps.
Research on English language teaching and learning in Argentina (2014–2018)
Authors: Porto Melina , López-Barrios Mario , Banegas Darío Luis
Published: May 2021

The aim of this article is to review five years (2014–2018) of research in English language teaching (ELT) in Argentina. In this overview, 115 publications (conference proceedings, journal articles, and edited collections) were analysed in terms of topic and research methodologies to map out the major areas of interest and developments in ELT in Argentina. The publications are reviewed according to nine topics: (1) interculturality and citizenship, (2) language teacher education and professional development, (3) technology-enhanced language learning, (4) learner differences, (5) language skills development, (6) language systems, (7) English for academic and specific purposes, (8) assessment, and (9) language curriculum development. The review discusses trends in research practices identified in the 2014–2018 period and suggests implications and further areas of inquiry to advance research skills as well as knowledge of ELT.
Pardoning Infanticide in Late Medieval France
Authors: McDougall Sara
Published: May 2021

The handling of infanticide in late medieval France offers modern audiences an underappreciated paradox: on the one hand infant murder was deplored as grave sin and crime, on the other hand, it was a pardonable offence, even the infanticidal singlemother who had killed to conceal her sin could obtain royal grace. This is far more than the usual story of law differing from practice. Christian ideology of mercy and forgiveness for sin played a central role in shaping the regulation of illegitimate births as well as abortions, stillbirths, and infanticide. Church and secular authorities alike sought to prevent as well as punish the death of infants, but they also created and implemented systems of justice with the explicit purpose of providing mercy to the repentant murderer, even an infanticide.
A cluster of Shiga Toxin-producing Escherichia coli O157:H7 highlights raw pet food as an emerging potential source of infection in humans
Authors: Kaindama Lukeki , Jenkins Claire , Aird Heather , Jorgensen Frieda , Stoker Kelly , Byrne Lisa
Published: May 2021

In August 2017, a cluster of four persons infected with genetically related strains of Shiga toxin-producing Escherichia coli (STEC) O157:H7 was identified. These strains possessed the Shiga toxin (stx) subtype stx2a, a toxin type known to be associated with severe clinical outcome. One person died after developing haemolytic uraemic syndrome. Interviews with cases revealed that three of the cases had been exposed to dogs fed on a raw meat-based diet (RMBD), specifically tripe. In two cases, the tripe had been purchased from the same supplier. Sampling and microbiological screening of raw pet food was undertaken and indicated the presence of STEC in the products. STEC was isolated from one sample of raw tripe but was different from the strain causing illness in humans. Nevertheless, the detection of STEC in the tripe provided evidence that raw pet food was a potential source of human STEC infection during this outbreak. This adds to the evidence of raw pet food as a risk factor for zoonotic transmission of gastrointestinal pathogens, which is widely accepted for Salmonella, Listeria and Campylobacter spp. Feeding RMBD to companion animals has recently increased in popularity due to the belief that they provide health benefits to animals. Although still rare, an increase in STEC cases reporting exposure to RMBDs was detected in 2017. There has also been an increased frequency of raw pet food incidents in 2017, suggesting an increasing trend in potential risk to humans from raw pet food. Recommendations to reduce the risk of infection included improved awareness of risk and promotion of good hygiene practices among the public when handling raw pet food.
Unpacking complexities in ethnic–racial socialization in transracial adoptive families: A process-oriented transactional system
Authors: Pinderhughes Ellen E. , Matthews Jessica A. K. , Zhang Xian , Scott Judith C.
Published: May 2021

Over 50% of adoptions are transracial, involving primarily White parents and children of color from different ethnic or racial backgrounds. Transracial adoptive (TRA) parents are tasked with providing ethnic–racial socialization processes (ERS) to support TRA adoptees’ ethnic–racial identity development and prepare them to cope with ethnic–racial discrimination. However, unlike nonadoptive families of color, TRA parents lack shared cultural history with adoptees and have limited experience navigating racial discrimination. Knowledge of ERS among TRA families has centered on unidirectional processes between parenting constructs, ERS processes, and children's functioning. However, ERS processes in this population have complexities and nuances that warrant more sensitive and robust conceptualization. This paper proposes a process-oriented dynamic ecological model of the system of ERS, situating transacting processes in and across multiple family levels (parent, adoptee, family) and incorporating developmental and contextual considerations. With its framing of the complexities in ERS among TRA families, the model offers three contributions: a conceptual organization of parenting constructs related to ERS, a more robust understanding of ERS processes that inform how parents provide ERS, and framing of transacting processes within and between parenting constructs, ERS processes, and children's functioning. Implications for research, policy, and practice are discussed.
Crossroads in juvenile justice: The impact of initial processing decision on youth 5 years after first arrest
Authors: Cauffman Elizabeth , Beardslee Jordan , Fine Adam , Frick Paul J. , Steinberg Laurence
Published: May 2021

The current study advances past research by studying the impact of juvenile justice decision making with a geographically and ethnically diverse sample (N = 1,216) of adolescent boys (ages 13–17 years) for the 5 years following their first arrest. Importantly, all youth in the study were arrested for an eligible offense of moderate severity (e.g., assault, theft) to evaluate whether the initial decision to formally (i.e., sentenced before a judge) or informally (i.e., diverted to community service) process the youth led to differences in outcomes. The current study also advanced past research by using a statistical approach that controlled for a host of potential preexisting vulnerabilities that could influence both the processing decision and the youth's outcomes. Our findings indicated that youth who were formally processed during adolescence were more likely to be re-arrested, more likely to be incarcerated, engaged in more violence, reported a greater affiliation with delinquent peers, reported lower school enrollment, were less likely to graduate high school within 5 years, reported less ability to suppress aggression, and had lower perceptions of opportunities than informally processed youth. Importantly, these findings were not moderated by the age of the youth at his first arrest or his race and ethnicity. These results have important implications for juvenile justice policy by indicating that formally processing youth not only is costly, but it can reduce public safety and reduce the adolescent's later potential contributions to society.
Leveraging science to inform social policy: How Ed Zigler created a movement
Authors: Bogard Kimber , Takanishi Ruby
Published: May 2021

Ed Zigler believed that developmental science should be applied to policy, programs, and practices to improve the lives of children and families. He shared this belief with others and paved the way for alternative career pathways. This paper describes how Ed influenced others to connect science with program development, evaluation, and policy, and created networks of applied scholars. Ed Zigler's influence is broad and spans beyond academia to influencer organizations. We weave our own professional experiences throughout the paper, which we organized around three lessons we learned from Ed: (a) explore alternative career pathways and build the field; (b) start with the science and think application; (c) apply the knowledge and influence policy.
Activation and activity of plasma membrane H+-ATPase: key events in germinating Vicia faba seeds
Authors: Obroucheva N.V. , Lityagina S.V. , Sinkevich I.A.
Published: May 2021

The regulation of plasma membrane H+-ATPase was considered in imbibing Vicia faba seeds, a distinctive feature of which is germination by cell elongation, whereas the mitotic activity starts later. The enzyme activation is known to precede germination because it provides H+ ion efflux from the cytoplasm to cell walls which favours their modification and loosening, being the prerequisites of cell elongation commencement. The presence of an enzyme in imbibing embryo axes was confirmed immunochemically. H+ ion efflux was recorded with a pH-meter as acidification of ambient solution by the embryonic axes for 5 min. The activation of the enzyme and its subsequent activity are regulated in different ways. Enzyme activation is hydration-driven, it starts when water content increases up to the threshold level of 55% (fresh weight basis). This value was confirmed by imbibition in the presence of the osmoticum polyethylene glycol 6000, at various osmotic potentials. The activation does not depend on indolylacetic or abscisic acid treatment. Hydration-triggered activation of the enzyme favours rapid seed germination and its correspondence to the soil water potential. Enzyme activity after its activation is inhibited by 60–70% by 10−5–10−7 M abscisic acid, whereas indolylacetic acid exerted no effect. The regulation of plasma membrane H+-ATPase activity is presumably accomplished by the interaction of the enzyme with 14-3-3 proteins and endogenous fusicoccin, present in imbibing axes.
Feasibility and Acceptance of Direct-to-Home Tele-neuropsychology Services during the COVID-19 Pandemic
Authors: Parsons Michael W. , Gardner Melissa M. , Sherman Janet C. , Pasquariello Kathryn , Grieco Julie A. , Kay Christina D. , Pollak Lauren E. , Morgan Amy K. , Carlson-Emerton Britt , Seligsohn Karen , Davidsdottir Sigurros , Pulsifer Margaret B. , Zarrella Giuliana V. , Burstein Sarah M. , Mancuso Sarah M.
Published: May 2021

Objective:

Neuropsychological assessment via video conferencing has been proposed during the COVID-19 pandemic. Existing literature has demonstrated feasibility and acceptance of neuropsychological measures administered by videoconference, although few studies have examined feasibility and patient acceptance of TNP visits directly to patients’ homes (DTH-TNP).

Methods:

We modified a previously published patient satisfaction survey for DTH-TNP and developed a clinician feasibility survey to examine experiences during DTH-TNP.

Results:

Seventy-two patients (age range: preschool-geriatric) evaluated by DTH-TNP for cognitive problems at an academic medical center responded to voluntary surveys between April 20, 2020, and August 19, 2020, and 100% indicated satisfaction. Fifty-nine percent of patients reported limitations (e.g., technological concern) during the appointment. 134 clinician surveys were collected and indicated that clinicians achieved the goal of their appointment in 90% of encounters.

Conclusions:

These qualitative data suggest that patients and clinicians found DTH-TNP to be satisfactory during the COVID-19 pandemic, while also recognizing limitations of the practice. These results are limited in that voluntary surveys are subject to bias. They support the growing body of literature suggesting that DTH-TNP provides a valuable service, though additional research to establish reliability and validity is needed.
Age-Related Improvements in Executive Functions and Focal Attention in 22q11.2 Deletion Syndrome Vary Across Domain and Task
Authors: Maeder Johanna , Zuber Sascha , Schneider Maude , Kliegel Matthias , Eliez Stephan
Published: May 2021

Objective:

Executive functions (EF) and focal attention have been identified as a weakness in the profile of 22q11.2 deletion syndrome (22q11DS). However, due to a high variety of tasks used across previous studies, it remains unclear whether impairments may be more pronounced for specific subdomains of EF and focal attention. Furthermore, age-related changes have only been examined in a few studies, so far only yielding a partial view of the overall developmental profile.

Method:

In a broad age range (8–35 years) composed of longitudinal data, 183 participants (103 diagnosed with 22q11DS) completed an extensive assessment of EF and attention. To get a more comprehensive overview of specificversusglobal impairments, several tasks were assessed within multiple domains.

Results:

Results suggest differential impairments and trajectories in specific EF subdomains. Specifically, our findings suggest that individuals with 22q11DS not only showed lower overall inhibition skills, but also that initiation skills developed at a slower pace compared to healthy controls. Results are less clear regarding cognitive flexibility, updating and focal attention, for which performance strongly depended on the tasks that was selected to assess the domain.

Conclusions:

Findings confirm and extend knowledge on differential developmental patterns of EF and attention domains in 22q11DS. They further stress the necessity to administer extensive, multifaceted evaluations to gain a more reliable overview of patients’ cognitive profile.
Cancer care reform in South Africa: A case for cancer care coordination: A narrative review
Authors: Lubuzo Buhle , Hlongwana Khumbulani , Ginindza Themba
Published: May 2021

Objective

This review provides an overview of the existing literature on the importance of care coordination for lung cancer care and other cancers in general. The review is inclusive of the burden of cancer, with a special reference to lung cancer, as well as challenges and achievements relating to cancer care coordination.

Method

We conducted a search of online databases of peer-reviewed studies published in the English language. The analysis for this review has been packaged into themes in order to generate results that can inform researchers and cancer health professionals, on the existing gaps necessary for developing appropriate intervention strategies and policy guidelines.

Results

Cancer is a complex condition that often requires multiple interventions provided by a variety of health professionals within the healthcare continuum. This paper reviewed research studies that explored the supportive care needs of cancer patients. The results are presented in three superordinate themes, namely (a) cancer as a healthcare priority in South Africa (SA), (b) making a case for coordinated cancer care in SA, and (c) care coordination: a poorly defined, yet complex concept. One major need identified was the requirement of informational support. Other essential needs included referral, emotional, and financial support.

Significance of results

The identification of current obstacles has the potential to guide the development of a model to improve quality coordinated cancer health care. It remains that limited research exists around cancer services and cancer care in the South African region. This narrative review identified common elements and barriers to care for lung cancer patients and survivors, and offers recommendations for developing clinical care models.
Dignity-conserving palliative care in a diverse population: A qualitative study of physicians’ perspective
Authors: de Boer A.F. , de Voogd X. , Meershoek A. , Suurmond J.L.
Published: May 2021

Background

Preserving personal dignity is an important aim of palliative care. Little is known about how physicians perceive and preserve dignity of patients from non-western migration backgrounds. Insight in this is important given the increased demand for culturally sensitive palliative care.

Aim

To gain insight in how Dutch physicians perceive and preserve dignity in the last phase of life for patients from non-western migration backgrounds.

Design

Qualitative thematic analysis of semi-structured interviews.

Participants

Fifteen physicians experienced in palliative care.

Results

Physicians experienced dilemmas in preserving dignity of non-western patients in three situations: (a) relief of suffering in the terminal phase, (b) termination of interventions and treatment, and (c) disclosure of diagnosis. Physicians wanted to grant the needs of patients in the last phase of their lives, which was central to physicians’ view on dignity, but dilemmas arose when this conflicted with physicians’ other personal and professional values. To make the dilemmas manageable, physicians assessed whether needs of patients were authentic, but due to linguistic, cultural, and communication barriers, this was difficult with non-western patients. To find a way out of the dilemmas, physicians had three strategies: accept and go along with patient's wishes, convince or overrule the patient or family, or seek solutions that were acceptable for all.

Conclusions

Physicians encounter dilemmas providing palliative care for people from non-western backgrounds. Future physicians can be trained in connective strategies and seeking middle grounds to optimally preserve patients’ dignity while being in concordance with their personal and professional values.
Nurses’ involvement in end-of-life discussions with incurable cancer patients and family caregivers: An integrative review
Authors: Ikander T. , Raunkiær M. , Hansen O. , Dieperink K.B.
Published: May 2021

Aim

To review current evidence of nurses’ involvement in end-of-life discussions with incurable cancer patients and their family caregivers.

Design

We conducted a systematic integrative review in accordance with PRISMA guidelines: PROSPERO, registration number: CRD42020186204.

Data sources

CINAHL, Medline, PsycInfo, Embase. We searched for primary research between 2010 and 2020.

Results

Of 3,271 references, we found 15 eligible articles: qualitative (n = 12) and quantitative (n = 3). The studies focused on oncology nurses' perspective of involvement in end-of-life discussions. The data analysis resulted in four overall themes: (1) Nursing roles; the advocating, supporting, and reframing roles, and an undefined task, for example in medical consultations, (2) Trust building, (3) Nurse competences, and (4) Medical issues.

Significance of results

The nurses have several roles in end-of-life discussions, but insufficient competencies to be involved in that kind of discussions, for example to involve and communicate with families. The findings implicate an educational need among the nurses. However, it also points toward an organizational change in the outpatient clinics, for example that end-of-life discussions follow a more structured approach, are offered in a scheduled manner, and that nurses invite the family caregivers to attend.
General method for synthesizing dispersive coupling matrix of microwave bandpass filters
Authors: Zhang Yan , Wu Ke-Li
Published: May 2021

In this paper, a general method for synthesizing dispersive coupling matrix (DCM) of coupled-resonator bandpass filters with the general dispersion is proposed. Compared to the dispersion-less coupling matrix synthesized by classic approaches, the DCM incorporates the identity of the physical realization and provides an accurate description of the filter. Moreover, the DCM can accurately describe the complex resonators and coupling elements with intentional strong dispersion. A DCM consists of two parts: the frequency-invariant part that corresponds to the coupling matrix at the center frequency and the frequency-variant part that reflects the dispersion of the physical realization. By iteratively adjusting the transmission zeros governed by the given filter topology and ignoring the transmission zeros brought by the dispersion, the synthesis method can directly obtain the frequency-invariant part so that the overall DCM leads to an equal-ripple response. To illustrate the general synthesis method, two design examples are presented, which include a filter with unintentional weak dispersion and a filter with intentional strong dispersion. The examples are validated by EM simulation, demonstrating the effectiveness, accuracy, and generality of the proposed synthesis framework. Key words: dispersive coupling matrix, filter synthesis, microwave bandpass filter
Callous-unemotional Traits, moralische Identität und Bullying im Jugendalter
Authors: Schipper Neele , Koglin Ute
Published: May 2021

Zusammenfassung. Theoretischer Hintergrund: Die Rolle der Moral im Kontext pro- und antisozialer Verhaltensweisen wird sowohl national als auch international diskutiert. Im Zusammenhang mit antisozialen Verhaltensweisen von Jugendlichen werden zudem vermehrt Callous-unemotional Traits betrachtet. Fragestellung: Die vorliegende Studie untersucht den Zusammenhang zwischen CU-Traits, der moralischen Identität und Bullying. Methode: Insgesamt bearbeiteten N = 749 Jugendliche einen Fragebogenkatalog. SPSS und AMOS wurden zur Analyse der vorliegenden Daten genutzt. Ergebnisse: Die Ergebnisse zeigen direkte Effekte von Callousness, Uncaring und der moralischen Identität auf Bullying. Die Skalen Uncaring und Callousness zeigen einen Zusammenhang mit moralischer Identität und Bullying. Diskussion und Schlussfolgerung: Die Ergebnisse deuten an, dass die moralische Identität und die damit einhergehende moralische Entwicklung wichtige Prädiktoren für das Verhalten von Jugendlichen sind.
Zusammenhänge zwischen moralischer Ekelsensibilität und aggressivem Verhalten im Jugendalter
Authors: Bondü Rebecca , Groshcheva Neli , Wecke Miriam , Brutscher Silke
Published: May 2021

Zusammenfassung. Theoretischer Hintergrund: Moralische Ekelsensibilität (MES) beschreibt die Tendenz, sich von Normverstößen abgestoßen zu fühlen. Im Erwachsenenalter war MES negativ mit Aggression assoziiert; für das Jugendalter liegen kaum Studien vor. Fragestellung: Wir untersuchten, ob MES und Aggression im Jugendalter zusammenhängen und mit moralischer Ärgersensibilität (MÄS) zusammenspielt. Methode: 359 Jugendliche berichteten MES, MÄS, Formen und Funktionen von Aggression sowie verschiedene Kontrollvariablen. Ergebnisse: MES korrelierte negativ mit allen Aggressionsmaßen und sagte diese über MÄS hinaus vorher, nicht jedoch bei Berücksichtigung von Kontrollvariablen wie Ärgerneigung oder Neurotizismus. Diskussion und Schlussfolgerung: Moralische Ekelsensibilität hängt im Jugendalter negativ mit Aggression zusammen und lässt sich von moralischer Ärgersensibilität differenzieren. Sie verdient als moralbezogenes Trait daher weitere Aufmerksamkeit. Andere Variablen eigenen sich jedoch besser zur Prädiktion von Aggression.
Space‐Time Stress Variations on the Palu‐Koro Fault Impacting the 2018 Mw 7.5 Palu Earthquake and Its Seismic Hazards
Authors: Liu Chang , Shi Yaolin
Published: May 2021

In this study, we calculated the Coulomb stress change before and after the 2018 Palu earthquake (Mw 7.5) induced by historical large earthquakes on and around the Palu‐Koro fault (PKF) within Sulawesi Island, Indonesia. We found that the 1996 earthquake (Mw 7.9) on the Minahassa thrust likely promoted the 2018 Palu earthquake by stress loading on its hypocenter. Stress shadows in the PKF impacted the 2018 earthquake rupture’s southward unilateral propagation and termination. Stress increases in the two seismic gaps to the north and south ends of the PKF have resulted in increased seismic hazards, calling close attention to hazard prevention in central Sulawesi. This indicates that fault‐interaction‐induced stress variations on the PKF significantly controlled the 2018 Palu earthquake and its seismic hazards. Our study is important for understanding stress triggering between the subduction earthquakes and intraplate earthquakes in thrust and strike‐slip faults systems globally.
Influence of Zonal Wind Velocity Variation on Equatorial Plasma Bubble Occurrences Over Southeast Asia
Authors: Sarudin I. , Hamid N. S. A , Abdullah M. , Buhari S. M , Shiokawa K. , Otsuka Y. , Hozumi K. , Jamjareegulgarn P.
Published: May 2021

The present study aims to investigate the influence of the zonal wind velocity on equatorial plasma bubble (EPB) occurrences over Southeast Asia. The observation of the EPB occurrence is obtained from the GPS Rate of TEC change index. Meanwhile, the zonal winds were measured using a Fabry‐Perot interferometer located at Kototabang and Chiang Mai stations, and the height of F layer was acquired using an ionosonde at Chumphon station near the magnetic equator. This is the first study to report the influence of zonal wind velocity variation on EPB occurrences with the presence and absence of EPB using GPS data in the Southeast Asian sector. The results illustrated that the average magnitude of zonal wind velocity during the presence of EPB (78 ± 23 m/s) was higher than that of its absence (68 ± 21 m/s). It was observed using long‐term data analyses which led to in‐depth analyses. The analysis of temporal variation of zonal wind variation demonstrated that the zonal winds during EPB were higher in the evening compared to midnight and postmidnight periods from medium to high solar activities. The dependence of zonal wind velocity on EPB over local time was obtained based on the analysis which utilized the data collected during equinox in high solar activity. Besides that, a positive correlation was obtained between the zonal wind velocity and EPB occurrences during pre‐reversal enhancement (PRE) corroborated the effects of zonal wind influence on PRE, and thus EPB occurrences.
Global Observations and CMIP6 Simulations of Compound Extremes of Monthly Temperature and Precipitation
Authors: Wu Yi , Miao Chiyuan , Sun Ying , AghaKouchak Amir , Shen Chenwei , Fan Xuewei
Published: May 2021

Compound climate extremes, such as events with concurrent temperature and precipitation extremes, have significant impacts on the health of humans and ecosystems. This paper aims to analyze temporal and spatial characteristics of compound extremes of monthly temperature and precipitation, evaluate the performance of the sixth phase of the Coupled Model Intercomparison Project (CMIP6) models in simulating compound extremes, and investigate their future changes under Shared Socioeconomic Pathways (SSPs). The results show a significant increase in the frequency of compound warm extremes (warm/dry and warm/wet) but a decrease in compound cold extremes (cold/dry and cold/wet) during 1985–2014 relative to 1955–1984. The observed upward trends of compound warm extremes over China are much higher than those worldwide during the period of interest. A multi‐model ensemble (MME) of CMIP6 models performs well in simulating temporal changes of warm/wet extremes, and temporal correlation coefficients between MME and observations are above 0.86. Under future scenarios, CMIP6 simulations show substantial rises in compound warm extremes and declines in compound cold extremes. Globally, the average frequency of warm/wet extremes over a 30‐yr period is projected to increase for 2070–2099 relative to 1985–2014 by 18.53, 34.15, 48.79, and 59.60 under SSP1‐2.6, SSP2‐4.5, SSP3‐7.0, and SSP5‐8.5, respectively. Inter‐model uncertainties for the frequencies of compound warm extremes are considerably higher than those of compound cold extremes. The projected uncertainties in the global occurrences of warm/wet extremes are 3.82 times those of warm/dry extremes during 2070–2099 and especially high for the Amazon and the Tibetan Plateau.
A Multi‐Instrument Study of a Dipolarization Event in the Inner Magnetosphere
Authors: Matsui H. , Torbert R. B. , Spence H. E. , Argall M. R. , Cohen I. J. , Cooper M. B. , Ergun R. E. , Farrugia C. J. , Fennell J. F. , Fuselier S. A. , Gkioulidou M. , Khotyaintsev Yu. V. , Lindqvist P.‐A. , Matsuoka A. , Russell C. T. , Shoji M. , Strangeway R. J. , Turner D. L. , Vaith H. , Wygant J. R.
Published: May 2021

A dipolarization of the background magnetic field was observed during a conjunction of the Magnetospheric Multiscale (MMS) spacecraft and Van Allen Probe B on September 22, 2018. The spacecraft were located in the inner magnetosphere at L ∼ 6–7 just before midnight magnetic local time (MLT). The radial separation between MMS and Probe B was ∼1RE. Gradual dipolarization or an increase of the northward component BZ of the background field occurred on a timescale of minutes. Exploration of energization and Radiation in Geospace located 0.5 MLT eastward at a similar L shell also measured a gradual increase. The spatial scale was of the order of 1 RE. On top of that, MMS and Probe B measured BZ increases, and a decrease in one case, on a timescale of seconds, accompanied by large electric fields with amplitudes > several tens of mV/m. Spatial scale lengths were of the order of the ion inertial length and the ion gyroradius. The inertial term in the momentum equation and the Hall term in the generalized Ohm's law were sometimes non‐negligible. These small‐scale variations are discussed in terms of the ballooning/interchange instability and kinetic Alfvén waves among others. It is inferred that physics of multiple scales was involved in the dynamics of this dipolarization event.
Plain Language Summary Required for Submission to Journal of Geophysical Research: Solid Earth
Authors: Manighetti Isabelle , Abercrombie Rachel E. , Ben‐Zion Yehuda , Bernabé Yves , Bostock Michael , Dekkers Mark J. , Parman Stephen W. , Schmitt Doug , Tregoning Paul
Published: May 2021

The editors of JGR: Solid Earth announce that Plain Language Summaries will be required for all manuscripts.
Type I and III interferon responses in SARS-CoV-2 infection
Authors: Kim You-Me , Shin Eui-Cheol
Published: May 2021

Coronavirus disease 2019 (COVID-19), the current pandemic disease, is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Type I and III interferons (IFNs) are innate cytokines that are important in the first-line defense against viruses. Similar to many other viruses, SARS-CoV-2 has evolved mechanisms for evading the antiviral effects of type I and III IFNs at multiple levels, including the induction of IFN expression and cellular responses to IFNs. In this review, we describe the innate sensing mechanisms of SARS-CoV-2 and the mechanisms used by SARS-CoV-2 to evade type I and III IFN responses. We also discuss contradictory reports regarding impaired and robust type I IFN responses in patients with severe COVID-19. Finally, we discuss how delayed but exaggerated type I IFN responses can exacerbate inflammation and contribute to the severe progression of COVID-19.