bluuebunny/crossref_metadata_2025 huggingface dataset:
Herpes zoster duplex bilateralis asymmetrica
Authors: Arora Astha , Kucheria Monika , Bhalla Mala
Published: April 2023

Varicella zoster virus (VZV) causes varicella and herpes zoster (HZ). Lesions are commonly unilateral and dermatomal, but rarely more than one contiguous or two noncontiguous widely separated dermatomes may be involved. HZ duplex bilateralis (HZDB) is a very rare pattern and is indicative of some underlying immunosuppression. A 65-year-old female presented with multiple, grouped fluid-filled vesicles and crusted lesions over an erythematous base bilaterally in dermatomal distribution over the right upper limb (C8, T1) and left lower limb (L2, L3) since 3 days associated with pain, itching, and burning sensation. She was diagnosed as a case of HZ duplex bilateralis asymmetrica and treated with antivirals and supportive treatment. HZ is caused by reactivation of VZV remaining latent in the dorsal nerve root ganglion due to cell-mediated immunity after primary infection. Old age, recent mechanical trauma, and subsequent psychological stress might impair cell-mediated immunity can be implicated as a trigger for reactivation of VZV.
Histopathologic profile of cutaneous cystic lesions in teaching hospital, Nnewi, South-east, Nigeria
Authors: Ezejiofor Ifeoma F. , Olaofe Olaniyi O. , Ezejiofor Ogochukwu I. , Ukah Cornelius O. , Ozor Nnamdi S. , Enesi Adeiza S. , Osonwa Chukwuemeka N.
Published: April 2023

Background

A cyst is an enclosed space or abnormal sac within a tissue, usually containing fluid or semisolid matter and lined by epithelium.

Aims and objectives

To study all the cutaneous cystic lesions with respect to age, sex, anatomic site, and histologic types in a population of Nnewi, South-East Nigerian. It also aimed at highlighting the importance of histology in evaluating and preventing misdiagnoses encountered in cutaneous cystic lesions.

Patients and methods

A retrospective review was performed on the histopathology register on all histologically diagnosed cutaneous cysts at the Histopathology Department of Nnamdi Azikiwe University Teaching Hospital (NAUTH), Nnewi, Nigeria from 2011 to 2019.

Results

A total of 94 cutaneous cystic lesions, accounting for 1.3% (94/7204) of all surgical biopsy specimens, were included in this study. An overall clinicopathological correlation showed 26.6% (25/94) accuracy, but 73.4% were incorrectly diagnosed, with 7.4% (5/69) of cases misdiagnosed clinically as malignant lesions and one case of malignant cystic lesion diagnosed clinically as benign cyst. There were 49 males and 45 females, giving a slight male predominance, with male to female ratio of 1.1 : 1. The age ranged from 6 weeks to 79 years, with a mean±SD age of 26.5±21.1 years, and a peak age group of 0–10 years, representing 29.8% (28/94). Benign cutaneous cystic lesions were far commoner than malignant ones and included majorly epidermal inclusion cyst [37.2% (35/94)], pilar cyst [17.0% (16/94)], thyroglossal cyst [12.8% (12/94)], and dermoid cyst [8.5% (8/94)]. The only malignant cutaneous cyst was immature cystic teratoma [1.06% (1/94)]. The anatomic site most frequently affected was the head and neck [63.8% (60/94)].

Conclusion

Histopathologic evaluation is still the gold standard in eliminating misdiagnosis of these lesions. Epidermal inclusion cysts followed by pilar cysts were commonest cutaneous cystic lesions in our environment and occur more at the third decade and above, whereas cystic hygroma, dermoid cysts, and brachial cyst were predominant at the first decade of life.
Hypogonadism in men with obstructive sleep apnea and its related risk factors
Authors: Khaled Hesham N. , El-Helbawy Rana H. , El Gayed Eman M.A. , Khalaf Abdullah M.
Published: April 2023

Background

Sleep-related breathing disorders, including obstructive sleep apnea (OSA), have been linked to altered hypothalamic–pituitary–gonadal axis. Hypoxia, sleep fragmentation. and decreased deep sleep time in patients with OSA affect the hypothalamic–pituitary–gonadal axis, including serum luteinizing hormone (LH) and testosterone levels.

Purpose

To study serum levels of LH and testosterone in men with OSA and to investigate the possible risk factors that could affect their levels.

Patients and methods

This was a prospective cohort case–control study. The case group included 16 adult patients diagnosed with OSA confirmed by polysomnography. The control group included 16 matched healthy participants. Both groups were subjected to history taking, clinical examination, and investigations, including the Epworth sleepiness scale, BMI, neck circumference measurement, and serum levels of LH and testosterone.

Results

Patients with OSA had significantly higher mean levels of serum LH compared with healthy controls (P=0.031). The mean serum level of testosterone was lower in the OSA group compared with the matched controls; however, this difference was statistically insignificant (P=0.192). Among the studied risk factors for altered hormonal levels in patients with OSA, there was a significant positive correlation between desaturation index and serum LH levels (P=0.046) and a significant negative correlation between Epworth sleepiness scale and serum testosterone levels (P=0.025).

Conclusion

Our findings suggest that OSA in men is associated with a dysfunction in the hypothalamic–pituitary–gonadal axis, represented as high levels of serum LH. Although serum levels of testosterone were lower in patients with OSA, the study was underpowered to show a statistically significant difference.
Acquired Long Bone Defects Classifications
Authors: Semenistyy Anton A. , Komarov Artem V. , Sheridan Gerard A. , Rozbruch S. Robert , Solomin Leonid N.
Published: April 2023

Introduction:

In recent years, multiple classifications of long bone defects around the joint (LBDAJ) have been proposed. However, there is no universal clinical classification of LBDAJ to date. Through comprehensive literature review, we aim to identify the criteria that may be used to develop a future universal classification of LBDAJ.

Materials and Methods:

We performed a comprehensive review of the literature to identify all articles describing classification systems of LBDAJ in both native and prosthetic joints. Two reviewers searched the following electronic databases independently: The Cochrane Bone, Joint and Muscle Trauma Group, MEDLINE, and eLibrary. Studies investigating bone defects around the joint reporting a classification or any criteria to classify bone defects were included in this review. All studies not related to bone articular surfaces were excluded.

Results:

A total of 15 classifications for LBDAJ in the preserved joint were. Most systems considered the size of bone defect as a key criterion for clinical decision-making. A total of 31 classifications for periprosthetic bone defects related to hip, knee and shoulder arthroplasty were identified. The following criteria were used by different authors to classify periprosthetic bone defects: Location (n = 22), size (n = 20), containment (n = 9), discontinuity (n = 6), shape or geometrical characteristics of the defect (n = 4), fracture (n = 2), and deformity.

Conclusion:

Despite the large variety of the existing classifications of bone defects around the joint, there is no classification that could be considered universal. For the development of a future universal classification, defect location, size, and containment are likely to be the main factors to consider as important.
Prevalence of Vitamin D Deficiency in Adult Limb Lengthening and Deformity Correction Patients
Authors: Sax Oliver Charles , Mohamed Nequesha , Rivera Jessica C. , McClure Philip K. , Herzenberg John E.
Published: April 2023

Introduction:

Limb lengthening and deformity correction surgery (LLDC) requires adequate bone metabolism for distraction osteogenesis. Low Vitamin D is a common nutritional deficit that places bone health at risk and has been associated with fracture. It is currently unknown what the Vitamin D levels are among patients undergoing elective osteotomy. The goal of this research is to determine the prevalence of Vitamin D deficiency in adult patients undergoing lower extremity osteotomies for LLDC.

Materials and Methods:

A retrospective review was performed for adult patients (≥18 years old) who underwent an osteotomy surgery at a single institution between 2014 and 2018. The primary outcome measure was perioperative 25(OH)D serum level. Of 139 subjects identified as undergoing a lower extremity osteotomy surgery, 96 (69%) underwent perioperative Vitamin D testing. Deficiency and insufficiency were defined as a 25(OH)D value of <20 ng/mL and between 20 and 30 ng/mL, respectively.

Results:

Patients undergoing external fixator placement for length and/or deformity correction were most likely to have this laboratory assessed (88%) versus acute correction patients (65%) and intramedullary lengthening patients (62%), (P = 0.033). The mean Vitamin D level was 29.5 ± 17.8 ng/mL (range: 5.7–95.9 ng/mL). A total of 63% of patients had low perioperative Vitamin D: 33.3% deficient, 30.2% insufficient.

Conclusion:

The majority of adult LLDC patients have deficient or insufficient Vitamin D levels perioperatively. Vitamin D “prehabilitation” whereby testing and repleting before limb lengthening surgery should be highly considered as standard practice.
Bifocal Femoral Lengthening with Intramedullary Magnetic Lengthening Nail Following Osteotomy Propagation
Authors: Carter Jordan Taylor , Craft Madison , Dabash Sherif , Thabet Ahmed M. , Abdelgawad Amr
Published: April 2023

Techniques in limb lengthening have evolved since the early 1900s. The external fixation using an Ilizarov frame was the current gold standard. Recently, intramedullary devices have been utilized in limb lengthening procedures to avoid complications related to the bulky external fixators. Here, we present the case of a 41-year-old female with long-term limb length discrepancy (LLD) corrected with magnetically driven intramedullary nailing. An intraoperative fracture of the distal femur led to bifocal lengthening at both the osteotomy site and the fracture site. This case cautioned the orthopedic surgeons involved in limb lengthening surgery about potential complications that can happen during the procedure. It demonstrated the possible efficacy of bifocal lengthening procedures using a magnetically driven intramedullary nail in the setting of complex LLD.
Association of Serum Vascular Endothelial Growth Factor Levels with Nephropathy and Retinopathy in Type 2 Diabetic Patients
Authors: Hussin Hoyam Yousif , Hussein Waleed Abdelateif , Ibrahim Sabah A.E. , Almhdi Salih Abdelgader , Saeed Ali Awadallah , Abdrabo AbdElkarim A.
Published: April 2023

Introduction:

Vascular endothelial growth factor (VEGF), protein originally referred to as vascular permeability factor, maybe a signal protein produced by cells that stimulate the formation of blood vessels and a sub-family of growth factors. They are important signaling proteins engaged in both vasculogenesis and angiogenesis. It is a part of the system that restores the oxygen supply to tissues when blood circulation is insufficient like in hypoxic conditions. The serum concentration of VEGF is high in asthma and DM. The aim of this study to explore the relevance of VEGF level with the complication of diabetes mellitus (diabetic retinopathy [DR] and diabetic nephropathy (DN)).

Methodology:

Case–control study carried out in Khartoum–Sudan from August 2018 to August 2020. One hundred and four patients divided into four groups, 3 ml of blood were collected from each subject in sterile plain vacationer tube (3 ml) then was centrifuged, and the serum was stored at −20°C to measure VEGF level by using ELISA kits (E-EL-H0111, 96T).

Results:

We have confirmed previous observations of increased plasma VEGF Levels in patients with DR and DN. A total of 103 quality controls divided into four groups (diabetics with DR, diabetics with DN diabetics without DR or DN, and health individuals) were observed to determine the relationship between serum of VEGF levels and diabetes complication DR and DN.

Conclusions:

High level of VEGF plays a major role in the pathogenesis of DR and DN.
Does Bacterial Motility Influence the Extent of Bladder Wall Involvement in Women With Recurrent Urinary Tract Infections?
Authors: Patel Rahul S. , Christie Alana L. , Zimmern Philippe E.
Published: April 2023

Purpose:

Because bacterial motility has been implicated as a potential virulence factor, we compared the motile and nonmotile properties of bacteria isolated from urine cultures in women with recurrent urinary tract infections (RUTI) to test if such motility properties are linked to the extent of bladder wall infection on cystoscopy.

Materials and Methods:

After IRB approval, a retrospective review of women with antibiotic-recalcitrant symptomatic RUTI (≥3 Urinary tract infections/year) who underwent electrofulguration (EF) for cystitis was conducted. Pre-operative office cystoscopy staged cystitis as stage 1: trigone (trigonitis), stage 2: stage 1 and bladder base, stage 3: stage 2 and one or both lateral walls, and stage 4: the whole bladder (pancystitis). Positive urine cultures before EF for the type of bacteria (motile vs. non-motile) were compared among stages.

Results:

From 2006 to 2020, 139 women with RUTI met the study criteria. The median age was 67 with 95% Caucasian. Those with stage 4 cystitis were older (P = 0.0009) and less sexually active (P = 0.038). Patients with a higher stage were associated with a higher number of motile organisms (P = 0.0056), with an increased presence of non-E. Coli motile organisms (P < 0.0001) such as Proteus (P = 0.0024), Pseudomonas (P = 0.0062), Enterobacter (P = 0.020) and Citrobacter (P = 0.0067).

Conclusion:

The comparison of bacterial motility in women with RUTI at four different stages of bladder surface involvement identified unique characteristics and bacterial strains associated with each stage. RUTI women with higher stages of cystitis had more unique types of motile urinary bacterial strains, possibly suggesting a role in the spread of cystitis beyond the trigone.
Specific Mutations in APC, with Prognostic Implications in Metastatic Colorectal Cancer
Authors: Peng Huan , Ying Jun , Zang Jia , Lu Hao , Zhao Xiaokai , Yang Pengmin , Wang Xintao , Li Jieyi , Gong Ziying , Zhang Daoyun , Wang Zhiguo
Published: April 2023

Purpose Loss-of-function mutations in the adenomatous polyposis coli (APC) gene are common in metastatic colorectal cancer (mCRC). However, the characteristic of APC specific mutations in mCRC is poorly understood. Here, we explored the clinical and molecular characteristics of N-terminal and C-terminal side APC mutations in Chinese patients with mCRC.Materials and Methods Hybrid capture-based next-generation sequencing was performed on tumor tissues from 275 mCRC pati-ents to detect mutations in 639 tumor-associated genes. The prognostic value and gene-pathway difference between APC specific mutations in mCRC patients were analyzed.Results APC mutations were highly clustered, accounting for 73% of all mCRC patients, and most of them were truncating mutations. The tumor mutation burden of the N-terminal side APC mutations group (n=76) was significantly lower than that of the C-terminal side group (n=123) (p < 0.001), further confirmed by the public database. Survival analysis showed that mCRC patients with N-terminus side APC mutations had longer overall survival than C-terminus side. Tumor gene pathway analysis showed that gene mutations in the RTK/RAS, Wnt and transforming growth factor β signaling pathways of the C-terminal group were significantly higher than those of the N-terminal group (p < 0.05). Additionally, KRAS, AMER1, TGFBR2, and ARID1A driver mutations were more common in patients with C-terminal side APC mutations.Conclusion APC specific mutations have potential function as mCRC prognostic biomarkers. There are obvious differences in the gene mutation patterns between the C-terminus and N-terminus APC mutations group, which may have certain guiding significance for the subsequent precise treatment of mCRC.
A result on the invariant for powers of primes
Authors: Esipova Maria S. , Yeats Karen
Published: April 2023

The
$c_2$
invariant is an arithmetic graph invariant related to quantum field theory. We give a relation modulo p between the
$c_2$
invariant at p and the
$c_2$
invariant at
$p^s$
by proving a relation modulo p between certain coefficients of powers of products of particularly nice polynomials. The relation at the level of the
$c_2$
invariant provides evidence for a conjecture of Schnetz.
Spectrum of Helminth Infections in Migrants from Sub-Saharan Africa to Europe: A Literature Review
Authors: Grzegorek Katharina , Kroidl Inge , Prazeres da Costa Clarissa , Rothe Camilla
Published: April 2023

Sub-Saharan Africa (SSA) is endemic to numerous neglected tropical diseases, including many helminth diseases. With the migration of people from this part of the world to Europe, as has been happening on a large scale since 2015, these diseases are becoming more relevant to European physicians. This work aims to summarize the recent literature on this topic and to raise awareness of helminth diseases afflicting SSA migrants. The databases PubMed, Embase, and MEDLINE were screened for literature published in English and German between January 1, 2015 and December 31, 2020. In total, 74 articles were included in this review. The spectrum of helminth infections in migrants from SSA found in the literature review is broad; current research, however, is particularly focused on infections with Schistosoma spp. and Strongyloides stercoralis. Both diseases are often characterized by a long course, with few or no symptoms, with the risk of long-term organ damage. Successful and reliable screening for schistosomiasis and strongyloidiasis is strongly recommended. However, the current diagnostic methods lack sensitivity and specificity, rendering the diagnosis challenging and reliable assessment of disease prevalence difficult. Novel diagnostic methods and a greater awareness of these diseases are urgently needed.
Case Report: Autoimmune Pulmonary Alveolar Proteinosis after COVID-19: A Report of Two Cases
Authors: Saraswat Aatish , Pandey Indramani , Gupta Simple , Singh Manish , Peter Deepu
Published: April 2023

Autoimmunity has been extensively established as a characteristic feature of the post-COVID-19 syndrome. There is evolving evidence of immune system dysregulation leading to the development of autoimmune phenomena in patients with COVID-19. This immune dysregulation may range from the production of autoantibodies to the new onset of rheumatic autoimmune diseases. An extensive literature search in databases from December 2019 to date revealed that no cases of autoimmune pulmonary alveolar proteinosis (PAP) were reported in post-COVID patients. In this context, we report a novel case series of two cases of new-onset autoimmune PAP in post-COVID patients, an entity that has not been described before. We recommend further studies to better understand this association between new-onset autoimmune PAP and SARS-CoV-2.
Association between Livestock Ownership and Malaria Incidence in South-Central Ethiopia: A Cohort Study
Authors: Loha Eskindir
Published: April 2023

Zooprophylaxis is one of the possible environmental vector control strategies for malaria prevention. However, its effect on reducing malaria transmission has been questionable, requiring a detailed understanding of contextual factors. This study aims to evaluate the effect of keeping livestock on malaria incidence in south-central Ethiopia. A cohort of 34,548 people in a total of 6,071 households was followed for 121 weeks from October 2014 to January 2017. Baseline data were collected, including livestock ownership. Weekly home visits were done to actively search for malaria cases, and passive case detection was also carried out. Malaria was diagnosed with rapid diagnostic tests. Log binomial and parametric regression survival-time models were used to estimate effect measures. A total of 27,471 residents had complete follow-ups, and the majority (87.5%) lived in households owning livestock, including cattle, sheep, goats, and chickens. The overall incidence risk of malaria was 3.7%, and there was a 24% reduction in the risk of malaria among livestock owners. The total cohort contributed to 71,861.62 person-years of observation. The incidence rate of malaria was 14.7 cases per 1,000 person-years. There was a 17% reduction in the rate of malaria among livestock owners. Meanwhile, the protective effect of livestock ownership increased as the number of livestock or the livestock-to-human ratio increased. In conclusion, livestock owners had less malaria. In a setup where domestication of livestock is a common practice and the predominant malaria vector tends to feed more on livestock than humans, zooprophylaxis remains a promising strategy for malaria prevention.
Medico-legal analysis of cases of children who died suddenly due to pneumonia undiagnosed in their lifetime
Authors: Szczepański Michał , Skowronek Rafał , Sarecka-Hujar Beata , Kopyta Ilona
Published: April 2023

Pneumonia is one of the most common causes of children’s hospitalization and death. The aim of the study was a medico-legal analysis of children who died suddenly due to pneumonia undiagnosed in their lifetime. The research was of a retrospective character and consisted in an analysis of prosecution files. The study included 47 children who died between 2011-2018 in whom pneumonia after post-mortem examination was indicated as the cause of death, as well as children in whom the cause of death, despite additional post-mortem examinations, including histopathological tests, was not established. In some cases, under additional post-mortem examinations, additional targeted immunohistochemical staining of selected lung sections was performed to establish the diagnosis. In children with prodromal symptoms, histopathological examination showed significantly more frequent atelectasis than in children without prodromal symptoms. Pneumonia is a significant clinical problem. Especially in young children, it may proceed with- out any symptoms that would cause such a diagnosis to be made. A properly conducted post-mortem diagnosis supplemented by immunohistochemical examinations allows to reduce the number of unexplained deaths in children.
The age profile of court-appointed physicians in Poland. Status at the end of 2021
Authors: Smędra Anna , Berent Jarosław
Published: April 2023

The problems with obtaining expert opinions from court-appointed physicians in Poland have been known for a long time and are well-diagnosed. The reasons for this state of affairs are: an overall insufficient number of physicians compared to the general needs, uncompetitive remuneration levels, and the difficulty of reconciling professional and court-appointed expert duties, while taking into consideration the availability expected of experts. The ongoing generational transition may further exacerbate these problems. The purpose of this study was to investigate the latter phenomenon by comparing the age profile of court-appointed physicians with that of physicians in general. Information on the age of court-appointed physicians was obtained from the presidents of regional courts and the Central Register of Physicians, while general statistics on physicians were also acquired from the latter. Research allowed us to formulate the following conclusions: only 0.8% of all physicians in Poland serve a court-appointed expert function. Almost two-thirds of court-appointed physicians belong to the Baby Boomer generation (born in 1946-1964), nearly one-third to Generation X (1965-1980), and only one-sixteenth (6.10%) to Generation Y (1981-1996), or Millennials. The results obtained, as well as data from the literature, suggest that the current bad state of affairs regarding access to the opinions of court-appointed physicians will further deteriorate in the coming years due to generational changes, i.e., the replacement of Baby Boomers and Generation X, currently dominant among court-appointed experts, by Generation Y, i.e., Millennials, with a different attitude to life.
Development of a procedure involving artifact examination to determine the species affiliation of its biological material, as illustrated by an attempt to demystify an alleged Nazi lampshade made from human skin
Authors: Trzciński Maciej , Karpiewska Anna , Hałoń Agnieszka , Jonkisz Anna , Lebioda Arleta , Jurek Tomasz , Dobosz Tadeusz
Published: April 2023

Objectives: The main purpose of the study was to identify the species origin of the material from which the incriminating lampshade bought at a flea market had been made.

Methods: The histological and molecular biology methods commonly used in forensic genetics were selected to achieve this goal. The DNA for the research was isolated using a QIAamp DNA Mini Kit (Qiagen) according to the manufacturer’s protocol for tissues. The quantitative and qualitative evaluation of genetic material was carried out by the real-time PCR method with a Quantifiler Duo DNA Quantification Kit (Applied Biosystems). Specific genetic markers of mtDNA of cattle, equines, deer, wild boar, and sheep were selected to identify species.

Results: Histological tests showed that the lampshade had been made from intestinal flaps. The DNA from sample tested positive for cattle. The test results dispelled the suspicion that the researched lampshade had been made from human skin.

Conclusions: The proposed testing method can be used to verify the origin of the artifacts misleadingly described as made from human skin. To our knowledge, such artifacts can be found in museums and private collections. Further-more, it has been widely believed until now that human-skin products, mainly lampshades, were mass-produced in Nazi concentration camps, mainly in Buchenwald.
All about My Mother… Cilissa, Apollo and the Unity of the Oresteia
Authors: Pypłacz Joanna
Published: April 2023

The aim of this article is to reveal the connection between Cilissa’s speech in the Choephoroi and the infamous speech made by Apollo in the Eumenides. The analysis shows that if these two passages are treated separately, the former would seem to be a comic interlude that has been randomly inserted into the text, while the latter would seem to be weird, convoluted and even downright outrageous. However, if they are juxtaposed and analysed together as two chapters of Aeschylus’ explanation of the nature of motherhood, they become one sensible statement about the fact that mother is much more than a parent in the technical sense of the term. While the speeches of Cilissa and Apollo simply cast light on the issue of responsible motherhood and also on the harmful effects of ‘outsourcing’ the care of newborn children in ancient Greece, the fact that the link between these two speeches has been overlooked makes their interpretation very problematic, as do the failings of contemporary criticism, these being the anachronic approach and also the fact that translations are treated on a par with (or, sadly, given preference to) the original text, thus giving Aeschylus the undeserved reputation of being a ‘sexist’ or ‘misogynistic’ poet.
Słoweński patriotyzm w okresie socjalistycznej Jugosławii
Authors: Kubik Damian
Published: April 2023

Slovenian Patriotism in the Socialist Yugoslavia

The article presents an analysis of the essence and form of Slovenian patriotism in the socialist Yugoslavia, with particular emphasis on the 1980s (when the crisis of the Yugoslav idea becomes evident). It deals with issues related to the forms and manifestations of the patriotism of a small nation such as the Slovenes, who for most of their history were under the domination of larger and stronger nations. The argument is divided into five parts. The first, introductory one contains a brief outline of the ideological foundations of the Yugoslav federation, which were also important for the Slovenian patriotism at that time. For this purpose, the most important ideas and values promoted by Titoism in politics and education are recalled, and the progressive national and cultural emancipation of Slovenes is indicated. The second part discusses the views and positions of Slovenian intellectuals (Edvard Kocbek, Primož Kozak and Drago Jančar) fundamental to the understanding of the discussed issue. They are an expression of a deep reflection on the condition and position of a small nation in the specific conditions of a multinational federation, but also with reference to a wider (i.e. European and American) framework. The third part shows the Yugoslav background of discussions on Slovenian patriotism, which, in the rest of Yugoslavia in the 1980s, was considered nationalism shattering the federal unity. In the fourth part, the symbolic forms of “love for the homeland” in Slovenia (including those in tourism and sports) are cited, emphasizing their importance in the process of shaping the national awareness. The last part outlines the contemporary perception of Slovenian patriotism in the period of socialist Yugoslavia. The conclusion emphasizes, above all, the departure from patriotism based on the universalist ideology of socialism in favor of patriotism understood as love for the native land.
Innovative culture of teachers – part of organisational culture
Authors: Pîrău Lucia , Baciu Sergiu
Published: April 2023

The development of the innovative culture of the teachers will be possible and efficient only if it is based on theoretical and praxiological patterns of their innovative culture. In this context, the scientific issue that follows to be under discussion consists in strengthening the theoretical and praxiological concepts of the teachers’ innovative culture development, and the elaboration of a pedagogical model for the development of the teachers’ innovative culture that will contribute to a change in education. This thesis is a theoretical study of interdependence and influence of organisational culture on innovative culture. The lack of studies of innovative culture of the teaching staff within a general education establishment has entailed theoretical research of the already existent scientific findings and of the results of the studies made by professionals, particularly, in the sphere of business and entrepreneurship. There has been made a synthesis of the specialised literature concerning the definitions of the concept of organisational culture and types of cultures that would have either a positive, or a negative impact on the values, rules and innovative behaviour within the organisation. The studies provide the triggering factors of innovative culture and preconditions for development and formation of innovative culture, as well as the dimensions of such innovative culture.

Innowacyjna kultura nauczycieli – część kultury organizacyjnej
Rozwój kultury innowacyjnej nauczycieli będzie możliwy i skuteczny tylko wtedy, gdy zostanie oparty na teoretycznych i prakseologicznych wzorcach ich kultury innowacyjnej. W tym kontekście następna problematyka naukowa polega na wzmocnieniu teoretycznych i prakseologicznych koncepcji rozwoju kultury innowacyjnej nauczycieli oraz wypracowaniu pedagogicznego modelu rozwoju kultury innowacyjnej nauczycieli, który przyczyni się do zmiany Edukacja. Niniejsza praca jest teoretycznym studium współzależności i wpływu kultury organizacyjnej na kulturę innowacyjną. Brak badań nad kulturą innowacyjną kadry pedagogicznej w placówce szkolnictwa ogólnokształcącego pociągnął za sobą konieczność teoretycznego zbadania dotychczasowego dorobku naukowego oraz wyników badań dokonywanych przez profesjonalistów, zwłaszcza w sferze biznesu i przedsiębiorczości. Dokonano syntezy literatury specjalistycznej dotyczącej definicji pojęcia kultury organizacyjnej oraz rodzajów kultur, które miałyby pozytywny lub negatywny wpływ na wartości, zasady i zachowania innowacyjne w organizacji. W badaniach przedstawiono czynniki wyzwalające kulturę innowacyjną oraz warunki rozwoju i kształtowania się kultury innowacyjnej, a także wymiary tej kultury innowacyjnej.
Sense of career success in the experiences of seniors
Authors: Pikuła Norbert G.
Published: April 2023

The research and scientific discussion in the paper focuses on the category of the sense of career success. In the theoretical part, main assumptions referring to this category are presented: work, the value of work, the sense of career success. They determined the direction of the scientific investigation. The study was conducted within the qualitative paradigm. The research questions were answered using the qualitative interview method. The analysis and interpretation of the data obtained led to conclusions regarding the sample interviewed, as well as recommendations regarding further studies of the categories identified.

Poczucie sukcesu zawodowego w doświadczeniach seniorów

W prezentowanym artykule podstawą rozważań naukowo-badawczych uczyniono kategorię poczucia sukcesu zawodowego. W części teoretycznej zaprezentowano podstawowe przesłanki odnosząca się do kategorii tj. praca, wartość pracy, poczucie sukcesu zawodowego, co wyznaczyło kierunek projektu badawczego. Badania przeprowadzono zgodnie z założeniami paradygmatu jakościowego. Zastosowana metoda wywiadu jakościowego umożliwiła uzyskanie odpowiedzi na postawione pytanie badawcze. Analiza i interpretacja danych uzyskanych w toku badań uprawniła do sformułowania wniosków w odniesieniu do grupy badanej, a także wskazania kierunku dalszych badań w zakresie wyłonionych kategorii.
Правовое регулирование государственной гражданской службы в судах Французской Республики
Authors: Попов А.А.
Published: April 2023

В КОНТЕКСТЕ РАССМОТРЕНИЯ ВОПРОСА О ВЫДЕЛЕНИИ ГОСУДАРСТВЕННОЙ СУДЕБНОЙ СЛУЖБЫ В САМОСТОЯТЕЛЬНЫЙ ВИД ГОСУДАРСТВЕННОЙ СЛУЖБЫ РОССИЙСКОЙ ФЕДЕРАЦИИ АВТОРОМ ПРОВЕДЕНО ИССЛЕДОВАНИЕ ПРАВОВОГО РЕГУЛИРОВАНИЯ ГОСУДАРСТВЕННОЙ ГРАЖДАНСКОЙ СЛУЖБЫ В СУДАХ ФРАНЦУЗСКОЙ РЕСПУБЛИКИ, ПО ИТОГАМ КОТОРОГО СФОРМУЛИРОВАНЫ СЛЕДУЮЩИЕ ВЫВОДЫ: 1) ГОСУДАРСТВЕННАЯ СЛУЖБА В СУДАХ ЯВЛЯЕТСЯ ВИДОМ ЕДИНОЙ ГОСУДАРСТВЕННОЙ ГРАЖДАНСКОЙ СЛУЖБЫ РЕСПУБЛИКИ, КОТОРУЮ ПРОХОДЯТ СЕКРЕТАРИ СУДЕБНОЙ СЛУЖБЫ; 2) ПРАВОВОЙ ОСНОВОЙ СТАТУСА УКАЗАННЫХ ДОЛЖНОСТНЫХ ЛИЦ ВЫСТУПАЮТ ОБЩИЙ КОДЕКС ГОСУДАРСТВЕННОЙ ГРАЖДАНСКОЙ СЛУЖБЫ, ОПРЕДЕЛЯЮЩИЙ ОБЩИЕ ПРАВИЛА, ПРИМЕНИМЫЕ К ГРАЖДАНСКИМ СЛУЖАЩИМ, А ТАКЖЕ ДЕКРЕТ № 2015-1275 ОТ 13.10.2015 «ОБ ОСОБОМ СТАТУСЕ СЕКРЕТАРЕЙ СУДЕБНОЙ СЛУЖБЫ»; 3) ЗАМЕЩЕНИЕ ДОЛЖНОСТИ СЕКРЕТАРЯ СУДЕБНОЙ СЛУЖБЫ ПРОИСХОДИТ ПУТЕМ ПРОВЕДЕНИЯ ОТКРЫТОГО КОНКУРСА ИЛИ ПРОФЕССИОНАЛЬНОГО ЭКЗАМЕНА; 4) ПРОДВИЖЕНИЕ ПО СЛУЖБЕ ГРАЖДАНСКИХ СЛУЖАЩИХ СУДА ВКЛЮЧАЕТ В СЕБЯ ПОВЫШЕНИЕ ПО ДОЛЖНОСТИ И В РАНГЕ (ЗВАНИИ); 5) НА СЕКРЕТАРЕЙ СУДЕБНОЙ СЛУЖБЫ РАСПРОСТРАНЯЮТСЯ ПОЛОЖЕНИЯ, КАСАЮЩИЕСЯ НЕСОВМЕСТИМОСТИ ЗАМЕЩЕНИЯ ДОЛЖНОСТИ СУДЬИ С ОПРЕДЕЛЕННЫМИ ЗАКОНОМ ОБСТОЯТЕЛЬСТВАМИ.
Привлечение третьих лиц к исполнению коммерческих посреднических договоров комиссии
Authors: Филиппова С.Ю.
Published: April 2023

АВТОР РАССМАТРИВАЕТ ГЕНЕЗИС ЗАКОНОДАТЕЛЬСТВА О ДОГОВОРЕ КОМИССИИ И ВОЗМОЖНОСТИ ПРИВЛЕЧЕНИЯ ТРЕТЬИХ ЛИЦ К ИСПОЛНЕНИЮ ДОГОВОРНОГО ОБЯЗАТЕЛЬСТВА. АВТОР АНАЛИЗИРУЕТ ДОГОВОР СУБКОМИССИИ, ПРИХОДИТ К ВЫВОДУ О ТОМ, ЧТО ЭТОТ ДОГОВОР НЕ НОСИТ ПРОИЗВОДНОГО ХАРАКТЕРА, И ДАЕТ ПРАКТИЧЕСКИЕ РЕКОМЕНДАЦИИ ПО ФОРМИРОВАНИЮ УСЛОВИЙ ЭТОГО ДОГОВОРА.
Big Picard theorems and algebraic hyperbolicity for varieties admitting a variation of Hodge structures
Authors: Deng Ya
Published: April 2023

In this paper, we study various hyperbolicity properties for a quasi-compact K\"ahler manifold $U$ which admits a complex polarized variation of Hodge structures so that each fiber of the period map is zero-dimensional. In the first part, we prove that $U$ is algebraically hyperbolic and that the generalized big Picard theorem holds for $U$. In the second part, we prove that there is a finite \'etale cover $\tilde{U}$ of $U$ from a quasi-projective manifold $\tilde{U}$ such that any projective compactification $X$ of $\tilde{U}$ is Picard hyperbolic modulo the boundary $X-\tilde{U}$, and any irreducible subvariety of $X$ not contained in $X-\tilde{U}$ is of general type. This result coarsely incorporates previous works by Nadel, Rousseau, Brunebarbe and Cadorel on the hyperbolicity of compactifications of quotients of bounded symmetric domains by torsion-free lattices.

Comment: 31 pages. Final version, to appear in \'Epijournal de G\'eom\'etrie Alg\'ebrique
Investigation of Immunohistochemical Localization of Oxytocin Receptor in Diabetic and Non-Diabetic Mouse Heart
Authors: ARICI Serkan , BİNGÖL Seyit Ali
Published: April 2023

The aim of this study was to investigate the immunohistochemical localization of oxytocin receptor (OTR) in diabetic and non-diabetic mouse heart tissue. Eighteen male Balb-c adult (8-12 week) mice were used in the study. Animals were divided into three groups; control, sham and diabetes. The diabetes group was given STZ by intraperitoneally (i.p) injections and diabetes was induced. Sham group was again treated with sodium citrate solution by i.p. The animals in the control group did not receive any treatment. After 30 days of STZ application, mice were cervical dislocated under ether anesthesia and their heart tissues were removed. Each heart tissue was vertically divided into two parts and routine histological procedures were applied and then tissues were blocked in paraffin and sections were taken. For histological examination, Haematoxylin&Eosin (H&E), Crossman’s Triple staining and Periodic Acid Schiff (PAS) were applied to the sections. Immunoreactivity of OTR was determined by Avidin-Biotin-Peroxidase Complex (ABC) method. At the end of the study period; the body weight of the groups, blood glucose level, tissue weights and immunohistochemical localization of OTR in heart tissue samples and histological structure of tissue were compared. When weights of heart tissue were compared between the groups, there was no statistically significant difference between the groups (p>0.05). As a result of histological examinations, it was found that there was more degeneration in the cells in the myocardium of the heart in the diabetes group compared to the other groups. Immunohistochemical examinations showed that OTR showed similar immunoreactivity in sham and control groups. In the diabetic group, the immunoreactivity of OTR was similar in endothelial and capillary areas, but less in cell membrane, cytoplasm and purkinje cells. In conclusion, the results of this study showed that there is a significant relationship between the OTR, diabetes and heart tissue. As a result, it is thought that diabetes may have an effect on the cardiovascular system through the OTR (p
Intention to Use Induction Electric Stove According to Theory of Trying
Authors:   Management Master Program, Faculty of Economics and Business, Lambung Mangkurat University, Banjarmasin, Kurniawan Yekti
Published: April 2023

This research was conducted to examine the intention to use an induction electric stove according to the theory of trying. The variables involved in the analysis are traits, theory of trying, the attitude of adopting an induction electric cooker (AM) and the desire to adopt an induction electric cooker (IM). Traits are general self-confidence (GSC) and cynicism (Cyn). Theory trying is attitude towards success (AS), attitude towards failure (AF), attitude towards learning (IA). Respondents are 197 of the respondents in Indonesia. Respondents who deserved to be processed were 124. The questionnaire used Google form media. The analysis technique used is PLS SEM with the help of WarpPLS 7.0 software. The results obtained are Attitude towards success has a significant positive effect on the attitude of adopting an induction electric stove. Attitude towards failure has no negative and insignificant effect on attitude towards induction cooker adoption. Attitudes toward learning to use an induction cooker have a significant positive effect on attitudes towards the adoption of an induction cooker. Attitudes towards the adoption of induction hobs have a positive impact on the intention to adopt induction hobs. Confidence in general has a significant positive effect on attitudes towards success. Self-confidence in general has a significant negative effect on attitudes towards failure. Confidence in general has a significant positive effect on attitudes towards learning to use an induction electric stove. Cynicism has a significant negative effect on attitudes towards success. Cynicism has a significant positive effect on attitudes towards failure. Cynicism has a significant positive effect on attitudes toward learning to use an induction hob. There is a pattern that is different from previous research related to conversion plans, namely the obligation of the state and government support, both equipment and direct cash assistance related to the conversion program.
Measures to Increase the Financial Markets of Uzbekistan's Competitiveness in the Framework of Financial Globalization
Authors:   Master, Tashkent State University of Economics (Uzbekistan, Tashkent), Abdukayumov A.N.
Published: April 2023

One of the main features of the modern globalization of the world economy is manifested in the increase in the opportunities for effective use of human intellectual abilities in the free movement of capital, goods and services, and labor. Under the influence of this factor, developing countries have opportunities to use the advantages of globalization and increase the rate of socio-economic development. at the same time, when conducting economic policy, its neglect can lead to negative consequences.
The Botanical Lexicon of Latin Vegetable Materia Medica. A dictionary of nomenclature, taxonomy, and morphology of historical medicinal herbal materials. Part II - B
Authors:   Śląski Uniwersytet Medyczny w Katowicach, Drobnik Jacek
Published: April 2023

This dictionary reveals botanical information which stands behind the Latin nomenclature and Latin terminology of historical vegetable materia medica. Materia medica is a traditional name of both the plant-derived materials of any medicinal value, and the knowledge of them which evolved into pharmacognosy. The data were excerpted from scientific pharmaceutical sources published in Europe, North America (or other parts of the world but written by Europeans and Americans or by scientists educated therein) generally between 1700 and 1950.
Effects of Storage Methods on Sprouting and Nutritional Quality of Ginger (ZingiberofficinaleRosc) Rhizomes in Different Storage Periods
Authors: Stephen Olusoga , Olakunle Olaniyi , A. Babatola
Published: April 2023

Purpose: Harvested ginger rhizomes are highly vulnerable to damage during postharvest storage due to soil borne pathogens or pest attack. Experiments were conducted to evaluate the effects of storage methods required for sprouting and maintaining the nutritional quality of ginger rhizomes under different storage periods in the laboratory. 

Methods: The rhizomes were stored inside five different storage methods viz., refrigerator, clay pots, pit lined with sand, pit lined with sawdust and black polythene bag with twelve perforations at three different storage periods of one, two and three months. The experiment was laid out in a complete randomized design and randomized complete block design for laboratory and field experiment respectively, replicated three times. Data were collected on temperature, percentage weight loss of stored rhizomes, percentage sprouting, plant height, number of leaves, leaf area and nutritional quality of ginger rhizomes. Data were subjected to analysis of variance using Statistical Analysis System Software (SAS, 2005). Differences among treatment means were compared using Least Significance Difference (LSD) at 5% probability level.

Results: The storage methods significantly (P≤0.05) influenced the percentage sprouting, weight loss, growth parameters and nutritional quality of ginger at various storage periods. The highest growth parameters were recorded from rhizomes stored for three months while the least value was recorded from rhizomes stored for one month. Highest percentage sprouting (94.90%) was recorded from rhizomes stored inside pit-sawdust followed by polythene (85.25%) while least percentage sprouting (66.28 %) was recorded from refrigerator. Rhizomes stored inside clay pots recorded least percentage weight loss of 27.89% closely followed by pit-sawdust (28.45%) and retained the nutritional quality of ginger at various storage periods while rhizomes stored inside refrigerator recorded highest percentage weight loss of 62.78.%.

Conclusion: In conclusion, storage of rhizomes inside pit-sawdust as well as clay pots for a period of three months before planting produced better ginger growth on the field and maintain the quality of stored rhizomes.
Third Eye for the Blind using Ultrasonic Sensor
Authors: S. Raghul  , R. Priya  , Pilli Vijay Kumar  , Karri Lavanya  , C. Kavitha
Published: April 2023

The "Third Eye for Blind with Ultrasonic Glove" is made up of parts such as an Ultrasonic sensor, Water sensor, switch, GSM, buzzer, and vibration motors and is intended to help the blind overcome their lack of vision by employing other senses like sound and touch. It alerts the user of impending obstacles using audio and vibration cues. The frequency of the auditory and vibration messages rises as the distance between the glove and the obstruction decreases. Consequently, the technology aids in making navigating easier for those in need. The sensor module uses ultrasonic waves to calculate an object's length to estimate distance using the SONAR or RADAR principle. The fire is thus discovered by the Flame sensor. The system has a buzzer as well to produce an alarm sound. The system also includes a GPS and camera for locating and gathering photos and videos of those who are blind
Machine Learning and IoT Applications in Agriculture
Authors: S. D. Padiya  , Atharva Raut  , Bhavy Mittal  , Mayur Patel  , Vedant Polshettiwar
Published: April 2023

Agriculture is an industry that has historically relied on traditional methods for crop production, but with the advent of new technologies, it is now possible to integrate machine learning and Internet of Things (IoT) applications to improve agricultural practices. Machine learning algorithms and IoT devices can be used to analyze data collected from agricultural fields to optimize crop yield, reduce resource consumption, and improve farm management. In this review paper, we explore the various applications of machine learning and IoT in agriculture, specifically focusing on their use in crop monitoring, disease detection, and water management. We examine the challenges associated with implementing these technologies in agriculture, including issues related to data collection, privacy, and security. Finally, we discuss the potential benefits of integrating machine learning and IoT in agriculture and identify future research directions that can help advance this field. Overall, this review highlights the potential of machine learning and IoT technologies to revolutionize agriculture and improve food security in the years to come.
The Internet of Things (IoT) network must be integrated with sensors in order for "smart agriculture" to be a reality. At many layers of the IoT system architecture, machine learning (ML) techniques are incorporated to increase usefulness and capabilities. For agricultural systems to properly integrate with information technology, intelligent agricultural systems must be established, and all types of information created by agricultural systems must be integrated and analysed.The agriculture sector might undergo a transformation thanks to the fusion of machine learning (ML) and internet of things (IoT) technology. Precision agriculture and more economical resource usage are made possible by using IoT sensors to collect data on a variety of factors, including soil moisture, temperature, and nutrient levels. Then, using these data, ML algorithms may be used to forecast outcomes and improve decision-making. For example, they can forecast agricultural yields, spot disease or insect infestations, and suggest the best dates for planting and harvesting.